bluuebunny/crossref_metadata_2025_split huggingface dataset:
Continuous Gas Dehydration Using the Hygroscopic Ionic Liquid [EMIM][MeSO3] as a Promising Alternative Absorbent
Authors: Krannich Michel , Heym Florian , Jess Andreas 
Published: December 2015

AbstractContinuous gas drying experiments with the hygroscopic ionic liquid [EMIM][MeSO3] show that it can be a very promising alternative drying agent to the absorbent triethylene glycol (TEG) commonly used in industrial gas drying processes. The HTU/NTU model in combination with the correlations of Onda et al. for mass transfer coefficients can be applied for the design of an absorption process with [EMIM][MeSO3]. The major advantage of this ionic liquid (IL) is that well‐known problems associated with the regeneration of the absorbent TEG can be avoided using [EMIM][MeSO3] due to extremely low vapor pressure and possible regeneration with air. The drying capacity of the IL system is about two times higher compared to TEG. Hence, a simple plant design comparable to that of industrial adsorption plants might be applied.
Combined Experimental and Predictive Uncertainty of Quantitative Structure Property Relationship Models
Authors: Müller Karsten 
Published: December 2015

AbstractQuantitative structure property relationship (QSPR) models allow for estimation of unknown substance properties. Their accuracy is usually described by error metrics that compare the result of the estimation to an experimental value. However, it has to be kept in mind that measured values are not perfectly accurate as well. The actual reliability of a QSPR model is therefore often significantly lower than indicated by conventional error metrics. To deal with this issue, the combined experimental and predictive uncertainty (CEPU) is proposed. Analogously to error propagation in evaluation of experimental works, the reliability of estimation methods can be accessed by the root of the sum of the different squared contributions to overall uncertainty. Such a metric is able to describe the effects of experimental errors with uniform algebraic sign as well as of randomized experimental errors.
Trinuclear Cage‐Like ZnII Macrocyclic Complexes: Enantiomeric Recognition and Gas Adsorption Properties
Authors: Janczak Jan , Prochowicz Daniel , Lewiński Janusz , Fairen‐Jimenez David , Bereta Tomasz , Lisowski Jerzy 
Published: December 2015

AbstractThree zinc(II) ions in combination with two units of enantiopure [3+3] triphenolic Schiff‐base macrocycles 1, 2, 3, or 4 form cage‐like chiral complexes. The formation of these complexes is accompanied by the enantioselective self‐recognition of chiral macrocyclic units. The X‐ray crystal structures of these trinuclear complexes show hollow metal–organic molecules. In some crystal forms, these barrel‐shaped complexes are arranged in a window‐to‐window fashion, which results in the formation of 1D channels and a combination of both intrinsic and extrinsic porosity. The microporous nature of the [Zn312] complex is reflected in its N2, Ar, H2, and CO2 adsorption properties. The N2 and Ar adsorption isotherms show pressure‐gating behavior, which is without precedent for any noncovalent porous material. A comparison of the structures of the [Zn312] and [Zn332] complexes with that of the free macrocycle H31 reveals a striking structural similarity. In H31, two macrocyclic units are stitched together by hydrogen bonds to form a cage very similar to that formed by two macrocyclic units stitched together by ZnII ions. This structural similarity is manifested also by the gas adsorption properties of the free H31 macrocycle. Recrystallization of [Zn312] in the presence of racemic 2‐butanol resulted in the enantioselective binding of (S)‐2‐butanol inside the cage through the coordination to one of the ZnII ions.
Metal–Organic Frameworks Containing Missing‐Linker Defects Leading to High Hydroxide‐Ion Conductivity
Authors: Montoro Carmen , Ocón Pilar , Zamora Félix , Navarro Jorge A. R. 
Published: December 2015

AbstractThe ionic conductivity properties of the face‐centered cubic [Ni8(OH)4(H2O)2(BDP_X)6] (H2BDP_X=1,4‐bis(pyrazol‐4‐yl)benzene‐4‐X with X=H (1), OH (2), NH2 (3)) metal–organic framework (MOF) systems as well as their post‐synthetically modified materials K[Ni8(OH)5(EtO)(BDP_X)5.5] (1@KOH, 3@KOH) and K3[Ni8(OH)3(EtO)(BDP_O)5] (2@KOH), which contain missing‐linker defects, have been studied by variable temperature AC impedance spectroscopy. It should be noted that these modified materials exhibit up to four orders of magnitude increase in conductivity ‐values in comparison to pristine 1–3 systems. As an example, the conductivity value of 5.86×10−9 S cm−1 (activation energy Ea of 0.60 eV) for 2 at 313 K and 22 % relative humidity (RH) increases up to 2.75×10−5 S cm−1 (Ea of 0.40 eV) for 2@KOH. Moreover, a further increase of conductivity values up to 1.16×10−2 S cm−1 and diminution of Ea down to 0.20 eV is achieved at 100 % RH for 2@KOH. The increased porosity, basicity and hydrophilicity of the 1@KOH–3@KOH materials compared to the pristine 1–3 systems should explain the better performance of the KOH‐modified materials.
N‐Alkyl‐, 1‐C‐Alkyl‐, and 5‐C‐Alkyl‐1,5‐dideoxy‐1,5‐imino‐(l)‐ribitols as Galactosidase Inhibitors
Authors: Front Sophie , Gallienne Estelle , Charollais‐Thoenig Julie , Demotz Stéphane , Martin Olivier R. 
Published: December 2015

AbstractA series of 1,5‐dideoxy‐1,5‐imino‐(l)‐ribitol (DIR) derivatives carrying alkyl or functionalized alkyl groups were prepared and investigated as glycosidase inhibitors. These compounds were designed as simplified 4‐epi‐isofagomine (4‐epi‐IFG) mimics and were expected to behave as selective inhibitors of β‐galactosidases. All compounds were indeed found to be highly selective for β‐galactosidases versus α‐glycosidases, as they generally did not inhibit coffee bean α‐galactosidase or other α‐glycosidases. Some compounds were also found to be inhibitors of almond β‐glucosidase. The N‐alkyl DIR derivatives were only modest inhibitors of bovine β‐galactosidase, with IC50 values in the 30–700 μm range. Likewise, imino‐l‐ribitol substituted at the C1 position was found to be a weak inhibitor of this enzyme. In contrast, alkyl substitution at C5 resulted in enhanced β‐galactosidase inhibitory activity by a factor of up to 1000, with at least six carbon atoms in the alkyl substituent. Remarkably, the ‘pseudo‐anomeric’ configuration in this series does not appear to play a role. Human lysosomal β‐galactosidase from leukocyte lysate was, however, poorly inhibited by all iminoribitol derivatives tested (IC50 values in the 100 μm range), while 4‐epi‐IFG was a good inhibitor of this enzyme. Two compounds were evaluated as pharmacological chaperones for a GM1‐gangliosidosis cell line (R301Q mutation) and were found to enhance the mutant enzyme activity by factors up to 2.7‐fold.
Development of hyperrealistic simulations to teach concepts about colors
Authors: Martinez Borreguero Guadalupe , Naranjo Correa Francisco Luis , Perez Rodriguez Angel Luis , Suero Lopez Maria Isabel 
Published: December 2015

AbstractA set of computer simulations with a higher degree of realism is presented. These hyper‐realistic simulations, used to teach basic concepts about color, were developed using the POV‐Ray software. The main aim of these simulations is to provide our students with a didactic tool in addition to their traditional laboratory practice, which can be easily implemented in e‐learning teaching platforms. The simulations of optical systems developed have resulted in graphical outputs that achieve photographic quality, which helped our students, even those with less capacity for abstraction, to combat misconceptions about color. © 2015 Wiley Periodicals, Inc. Col Res Appl, 41, 330–332, 2016
Appearance of cytomegalovirus‐specific T‐cells predicts fast resolution of viremia post hematopoietic stem cell transplantation
Authors: Pelák Ondřej , Stuchlý Jan , Król Ladislav , Hubáček Petr , Keslová Petra , Sedláček Petr , Formánková Renata , Starý Jan , Hrušák Ondřej , Kalina Tomáš 
Published: December 2015

BackgroundCytomegalovirus (CMV) specific T‐cells are known to provide long‐term control of CMV reactivation, which is a frequent complication of hematopoietic stem cell transplantation. We have studied 58 pediatric patients after hematopoietic stem cell transplantation who suffered from CMV reactivation to reveal which functional T cell subset is best correlating with successful reactivation resolution and which protects from reactivation episode.MethodsDetection of 30 combinatorial subsets of four types of response to ex vivo CMV stimulation (IFNγ secretion, IL‐2 secretion, CD40L upregulation and degranulation) that were detectable on either CD8+ or CD4+ T cells through flow cytometry intracellular cytokine staining was used.ResultsWe found that the presence of CD8+ dual positive (IFNγ+ and IL‐2+) cells is the most accurate functional parameter that can predict fast resolution of CMV reactivation. Next, we show that the presence of CD8+ dual positive (IFNγ+ and IL‐2+) and CD8+ IFNγ+ cells provides a protective effect (a hazard risk of 0.28 (confidence interval 0.18 – 0.43) and 0.45 (CI 0.27 – 0.75), respectively) and the presence of corticotherapy increases the risk of reactivation (HR 2.47 (CI 1.82‐3.36)). Thus, a patient without corticotherapy and with both of the critical T cell subsets present has a cumulative 19.6 times lower risk of developing CMV reactivation than a patient on corticotherapy and without CD8+ dual positive (IFNγ+ and IL‐2+) or CD8+ IFNγ+ cells.ConclusionsWe have established parameters of CMV specific functional response ex vivo that can be used in assisting clinical management of patients with CMV reactivation. © 2015 International Clinical Cytometry Society
Non‐native tree in a dry coastal area in Hawai'i has high transpiration but restricts water use despite phreatophytic trait
Authors: Miyazawa Yoshiyuki , Dudley Bruce D. , Hughes R. Flint , Vandemark Joshua , Cordell Susan , Nullet Michael A. , Ostertag Rebecca , Giambelluca Thomas W. 
Published: December 2015

AbstractIn arid systems, phreatophytes are often among the most effective invaders because of their capacity to access and exploit groundwater resources otherwise unavailable to native vegetation. On Hawai'i Island, a non‐native phreatophyte, Prosopis pallida (kiawe), has invaded extensive dry lowland areas following its introduction in the 19th century. To better understand the influence of this invader on the host ecosystem, and vice versa, we determined transpiration characteristics of P. pallida by monitoring sap flux of mature individuals over an 18‐month period on the arid leeward coast of Hawai'i Island. Daily sap flux increased with increasing atmospheric vapour pressure deficit (D) and exhibited no clear response related to rainfall events or prolonged drought. Annual transpiration (i.e. 308 mm) was 80% higher than rainfall. Stomatal conductance decreased with increasing vapour pressure deficits more slowly than the theoretical stomatal conductance–D relationship that assumes stomatal regulation of leaf water potential above a critical level. While daily peak stomatal conductance was relatively high, it nonetheless appeared limited by high intrinsic water use efficiency (net photosynthetic rate per stomatal conductance), suggesting a constraint to unlimited groundwater absorption. In this young volcanic environment where rainfall is low and quite episodic, the success of this species likely stems from its anisohydric strategy even at the risk of cavitation, and it is altering the hydrological cycling of the areas where it is dominant. Copyright © 2015 John Wiley & Sons, Ltd.
Permanent catheter drainage system for palliation of diuretic‐resistant cardiac ascites
Authors: Bevan Jonathan , Penn Lee‐Anne , Mitchell Andrew R. J. 
Published: December 2015

AbstractWe report the case of a 69‐year‐old man with dilated cardiomyopathy treated with a permanent catheter drainage system for diuretic resistant cardiac ascites. At 1 year follow‐up, the patient had no heart failure related hospitalisations, displayed improved quality of life measures and had incurred no complications related to the catheter. Permanent tunnelled catheters are widely used to treat malignant ascites but may also be considered for palliation of cardiac ascites.
Oral approach‐avoidance: A replication and extension for European–Portuguese phonation
Authors: Godinho Sandra , Garrido Margarida Vaz 
Published: December 2015

AbstractPrevious research revealed that mouth movements influence attitudes. Covert subvocal articulations inducing muscular contractions resembling ingestion movements were preferred over expectoration‐like movements, unveiling a relationship between vocal muscles' wandering and motivational states such as approach and avoidance. These findings, explained in terms of embodied cognition, suggest that specific movements are directly connected to, and more importantly, automatically activate concordant motivational states. The oral approach‐avoidance effect was replicated using the original stimulus set and a new set of stimulus developed for Portuguese. Results from two high‐powered (totalN = 407), independent replications, revealed that the preference for inward words (over outwards) exists in both sets but to a greater extent in the pool phonetically adapted for Portuguese.
Dispersed Nickel Nanoparticles on Flower‐like Layered Nickel‐Cobalt Double Hydroxides for Non‐enzymic Amperometric Sensing of Glucose
Authors: Chen Jiao , Sheng Qinglin , Wang Yan , Zheng Jianbin 
Published: December 2015

AbstractThe article describes the preparation of supported nickel nanoparticles (NiNPs) by partial reduction of Ni,Co‐layered double hydroxide (NiCo‐LDH). The nanocomposites were characterized by X‐ray diffraction and their morphology and composition were characterized by scanning electron microscopy and transmission electron microscopy. The electrochemical properties of the nanocomposite were explored by cyclic voltammetry and amperometry, which revealed significant electrocatalytic behavior towards the oxidation of glucose. The resulted non‐enzymatic glucose sensor has a linear response to glucose in the 5.0 μM to 14.8 mM concentration range, a low detection limit of 1.6 μM, high sensitivity, and excellent selectivity.
Determination of Ethambutol in Aqueous Medium Using an Inexpensive Gold Microelectrode Array as Amperometric Sensor
Authors: Lima A. E. B. , Luz G. E. , Batista N. C. , Longo E. , Cavalcante L. S. , Santos R. S. 
Published: December 2015

AbstractIn this paper, gold microelectrode array (Au‐MEA) were employed to determination of ethambutol in aqueous medium. Au‐MEA was constructed with an electronic microchip integrated circuit. The standard curve (analytical curve) was constructed for a single microelectrode (ME) in a concentration range of 5.0×10−5 to 2.0×10−3 mol L−1, allowing estimation of both the limit of detection (LOD) (4.73×10−5 mol L−1) and the limit of quantification (LOQ) (1.57×10−4 mol L−1) for ethambutol. When the MEA was utilized, the LOD and LOQ were 1.55×10−7 and 5.18×10−7 mol L−1, respectively. Our results indicated that Au‐MEA can be utilized as amperometric sensors for ethambutol determination in aqueous media.
Building political will for HIV response: an operational model and strategy options
Authors: Brinkerhoff Derick W. 
Published: December 2015

SummaryAs global programs for HIV response look to transfer responsibility and financing increasingly to country governments, the political will to take on these responsibilities becomes increasingly prominent. However, defining and assessing political will are problematic; it involves intent and motivation, and thus is inherently difficult to observe. It is intimately connected to capacity and is contextually embedded. This article describes an operational model of political will comprised of seven components that are observable and measurable. Two case studies illustrate the application of the model and shed light on the interconnections among commitment, capacity and context: South Africa and China. Strategy options to build political will for HIV response identify possible actions for both government and civil society. Political will as a concept is most usefully viewed as integrated within larger political and bureaucratic processes, as a product of the complex array of incentives and disincentives that those processes create. However, this conclusion is not a recipe for discouragement or inaction. Agent‐based conceptualizations of policy change offer a solid grounding for building political will that supports HIV policy and programs. Copyright © 2015 John Wiley & Sons, Ltd.
Powdered Ca‐activated zeolite for phosphate removal from treated waste‐water
Authors: Hermassi Mehrez , Valderrama César , Moreno Natalia , Font Oriol , Querol Xavier , Batis Narjes , Cortina José L 
Published: December 2015

AbstractBACKGROUNDA powdered zeolitic material synthesised from fly ash (FA) (NaP1‐FA) and its calcium modified form (CaP1‐NA) were studied as sorbent materials for the recovery of phosphate from treated waste‐water effluents. Phosphate‐sorption equilibrium experiments were performed by varying the experimental conditions, including solution pH, phosphate concentration, and the presence of competing ions.RESULTSThe maximum phosphate‐sorption capacities were 57 ± 5 and 203 ± 11 mgP–PO4 g−1 for NaP1‐FA and CaP1‐NA, respectively. The sorption capacities of both zeolites in the pH range expected for waste‐water effluents (pH 7 to 9) were slightly dependent on pH, exhibiting maxima at pH 8. Phosphate removal proceeds through two main mechanisms: (a) surface complexation with ≅AlOH and ≅FeOH groups of the zeolitic structure or unreacted minerals from the FA; and (b) the formation of Ca–phosphate phases, mainly brushite.CONCLUSIONSThe removal mechanisms were confirmed by XRD analyses and P speciation. The stabilities of the phosphate‐loaded zeolite samples evaluated by the extraction experiments confirmed their potential availabilities in soil applications. Finally, the higher solubility of brushite compared with that of Hap makes this zeolitic material promising as a novel inorganic zeolite/CaP1‐NA/brushite fertiliser. © 2015 Society of Chemical Industry
Fluorescence microscopy study on the cytoskeletal displacements during sperm differentiation in the bush‐cricket Tylopsis liliifolia (Fabricius) (Orthoptera: Tettigoniidae)
Authors: Viscuso Renata , Federico Concetta , Saccone Salvatore , Bonaccorsi Bianca , Vitale Danilo G.M. 
Published: December 2015

ABSTRACTA study by fluorescence microscopy has been carried out on male gametes from testicular follicles, seminal vesicles, spermatophores, and seminal receptacles of the bush‐cricket Tylopsis liliifolia, focusing the attention on localization and movements of F‐actin and α‐tubulin during sperm differentiation, since data in this respect are lacking in the Orthoptera.F‐actin and α‐tubulin positivity was detected in the testicular follicles, in particular at the bridges connecting spermatids of a same clone and around their nucleus, during the first differentiation stages. During the following differentiation stages in the testes, F‐actin was found at one of the spermatid poles and then, during nucleus elongation, at the whole acrosomal region. A peculiar F‐actin‐positivity was found at the flagellum, more markedly immediately posterior to the nucleus, at the basal body region of the gametes from the testicular follicles and from the other examined districts. Other interesting data from our investigations concerns the α‐tubulin displacements during the differentiation stages of the spermatid and a constant absence of α‐tubulin‐positivity where the centrioles are located. No positivity was also found for both α‐tubulin and nuclear markers at the anterior region of the gamete, where the acrosomal wings are localized. Our results, compared with what is so far known in literature for the insects, lead us to assert that microfilaments and microtubules undergo gradual displacements, markedly in the testicular follicles, during the morphogenesis of the male gamete of T. liliifolia aimed to its organization and motility and probably also to its interaction with the female gamete. Microsc. Res. Tech. 79:81–88, 2016. © 2015 Wiley Periodicals, Inc.
Upwelling and Chl‐a spatiotemporal variability along the Galician coast: dependence on circulation weather types
Authors: Picado A. , Lorenzo M. N. , Alvarez I. , deCastro M. , Vaz N. , Dias J. M. 
Published: December 2015

ABSTRACTThe eastern boundaries of the world's oceans are among the most productive marine regions owing to the wind induced coastal upwelling. In this context, changes in coastal upwelling influence chlorophyll‐a (Chl‐a) concentration along the Northwest (NW) Iberian Peninsula (IP) coast. This work aimed to evaluate and quantify the influence of meteorological conditions defined by circulation weather types (CWTs) on upwelling and Chl‐a variability along the Galician coast. A seasonal (April–September and October–March) characterization of satellite wind‐derived upwelling index (UI) and Chl‐a concentration was performed dividing the Galician coast into three domains: western (North–south orientation), intermediate (Northeast‐Southwest orientation) and northern (West–east orientation) segments. Results revealed that UI and Chl‐a concentrations were different among the three coastal segments and seasons. The most favourable upwelling conditions and high Chl‐a levels occurred during April–September at western coast. During October–March, high‐primary production also occurred and therefore a correlation analysis was performed during winter between Chl‐a, UI and discharges of the main rivers. Chl‐a and discharges were strongly correlated (0.52 for Minho and 0.31 for Nalon), suggesting that Chl‐a during this period was related to signal contamination due to river discharge. The probability that Chl‐a or UI exceeded a certain value, given the occurrence of a specified CWT was computed. Results showed that along the western coastal segment the strongest relations between CWTs, upwelling and Chl‐a concentration were obtained during April–September when N and NE occurred, with probabilities higher than 70% for UI and 30% for Chl‐a. During winter only the NW type had statistically significant probabilities for UI (50%) and Chl‐a (30%). For the intermediate coastal segment during October–March (April–September), when E type occurred, high probabilities of upwelling and Chl‐a were observed [100% (66), 50% (25), respectively]. Finally, at the northern coastal segment, Chl‐a probability was highest (40–50%) under the S weather type for both seasons.