bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Trial Enrollment Diversity Dashboard for Acute Leukemia Clinical Research: Intervention Development and Cohort Analysis
Authors: Hantel Andrew , Walsh Thomas P. , Li Kelsey Y. , Awan Saima , Littlejohn Emerald , Lathan Christopher S. , Abel Gregory A. 
Published: October 2024

PURPOSE
Participation in acute leukemia clinical trials is inequitable across multiple sociodemographic categories. Tools that provide researchers with performance feedback on the representativeness of the patients they enroll are limited. We aimed to develop an electronic health record (EHR)–based dashboard to provide such feedback and to describe any enrollment inequities uncovered.

METHODS
We created a visual dashboard linking leukemia clinical trial registration and EHR data at the Dana-Farber Cancer Institute. Accuracy of a patient inclusion and assignment algorithm was tested with a target area under the receiver-operator curve (AUROC) of >0.90 against manual review. Demographic metric identification, visualization construction, and dashboard refinement were performed through stakeholder cognitive testing. Analysis of a recent 5-year cohort generated by the final algorithm assessed bivariate associations between enrollment and demographic metrics. Multivariable logistic regression included significant bivariate results.

RESULTS
The final algorithm assignment AUROC was 0.98. Metrics were identified and visualizations successfully constructed. Fourteen individuals participated in testing and identified areas for revision: category mergers, denominator filters, and data delivery preferences. In the initial cohort of 1,315 patients, 1,020 (77.6%) had enrolled in any study protocol: 553 (42.1%) in a treatment trial and 936 (71.2%) in a biobanking study. In a multivariable model, older age (odds ratio [OR], 0.83 [95% CI, 0.73 to 0.94]) and Non-Hispanic Black race-ethnicity (OR, 0.38 [95% CI, 0.18 to 0.82]) were associated with lower enrollment, and English primary language with higher enrollment (OR, 2.50 [95% CI, 1.30 to 4.79]).

CONCLUSION
We developed a research participation equity performance feedback dashboard for clinical researchers, and we identified actionable inequities. Next steps include feasibility and efficacy testing as well as implementation.
Voilà le peuple
Authors: St. Clair Robert 
Published: October 2024

Abstract
Why does it matter that we try to think through, together, as entrammeled with one another, the act and work of reading and “the political”? What is at stake in the question of textuality in the current context of crises and turns-away (from theorization, from critique) that have come to characterize the humanities as the forms and institutions of higher education find themselves increasingly subsumed by the logics and imperatives of neoliberalism? The present article proposes to think through and tarry with this problem by taking as a case study of sorts the reaction of a certain number of literary and cultural studies scholars in the field of nineteenth-century French and Francophone studies to a recent (or perhaps an ongoing) event in the United States and its relation to the mise-en-scène of a revolutionary event in Flaubert’s L’Éducation sentimentale, arguing ultimately that, in dark and disorienting times, literature—which perhaps does nothing so well as help us to grapple with the ways in which the past and the present, and thus any possible futurity, are mutually entrammeled with one another—may help us get certain ideas, if not infallibly right, a little less wrong where possible, where they may matter most.
Proust before Fascism
Authors: Paul Zakir 
Published: October 2024

Abstract
This article analyzes readings of Proust from the 1930s to the 1950s, a period when his work was supposedly forgotten. The first section examines passages by Céline, Kurt Wais, and Curzio Malaparte, for whom Proust’s fiction was symptomatic of the dissipation of the dominant classes. The second part of the essay turns to Benjamin, Bataille, and Blanchot, for whom his novel altered conventional notions of justice, desire, figural language, and the structure of time through the experience of writing. Across the political spectrum, readings of Proust pit the rhetoric of decadence against experience and experiment. The essay concludes that although the Recherche records political, social, and historical events—from the Dreyfus affair and a morphing class structure to the onset of the war—none of these readers saw it as an announcement of disasters to come.
“La destruction est notre manière de bâtir”
Authors: Kim Annabel L. 
Published: October 2024

Abstract
This article examines Quebecois author Kevin Lambert’s debut novel, Tu aimeras ce que tu as tué, a disquieting story of slaughtered children who come back to the Canadian town of Chicoutimi to live normal lives in it before destroying it. The apocalyptic dimension of this tale of destruction lives up to the etymological root of apocalypse, apokalyptein (“to uncover, disclose, reveal” in Greek) by centering the narrative around a revelation of the violence that is inherent to heteronormative culture but occulted by its position of dominance. This violence, which targets the figure of the innocent child, the standard-bearer of heterosexuality in its reproductive futurity, is, through the prophetic rage of the narrator, a child named Faldistoire, turned back upon the respectable adults who stamp out not only the lives of children but their nonnormative desires and impulses—their freedom. The novel puts forth apocalypse as a model for the work of literature itself—revelation that rends normative reality in order to replace it with something else.
Il faut imaginer Pasolini en Cassandre heureuse
Authors: Paquette Julie 
Published: October 2024

Résumé
En 1975, Pasolini raconte l’arrivée imprévisible d’une nouvelle forme de fascisme par la métaphore de la disparition des lucioles. Plus de quarante ans plus tard, Georges Didi-Huberman résume ainsi son propos : « Pasolini [contrairement à Benjamin] a fini par désespérer », rangeant d’un même élan Pasolini du côté des prophètes de malheurs. Une telle lecture paraît contestable. Pour en faire la démonstration, cet article s’attarde sur la figure de Cassandre dans le Carnet de notes pour une Orestie africaine (1970), et montre de quelle manière cette antique prophétesse s’inscrit, par le montage pasolinien, dans la lignée benjaminienne de la tradition des opprimés. C’est donc l’écho d’une Cassandre euripidienne dans l’écriture pasolinienne—tous deux se présentant comme des contemporains au sens où l’entend Agamben—qui ressort au terme de l’analyse, laquelle se conclut en imaginant Pasolini en Cassandre heureuse. Ce qui revient à le réhabiliter dans le champ benjaminien de la tradition de l’organisation du pessimisme.
Mourir, c’est apprendre à vivre . . .
Authors: Julliot Caroline 
Published: October 2024

Résumé
À l’aune de la polémique suscitée par la parution, en novembre 2022, de l’entretien que l’auteur a accordé à Michel Onfray pour sa revue Front Populaire, le présent article tente de réévaluer la posture, construite de longue date dans le discours médiatique, d’un Houellebecq « prophète déprimiste ». Après avoir défendu l’hypothèse que la réactivation, pour le moins anachronique, de la figure de l’écrivain prophète en révèle plus sur la crise du débat démocratique contemporain que sur l’auteur lui-même, il s’attache, notamment par l’analyse du récent roman Anéantir, à nuancer l’univocité du pessimisme qui se dégage de son œuvre. Et si, pour Houellebecq, l’imminence de la mort, de l’individu comme de la civilisation, était, in fine, la condition sine qua non au bonheur ; le seul moyen, dans une société de la compétition et de la performance, de s’extraire du samsara libéral et de sa propre obsolescence programmée pour profiter, simplement, au présent, de la vie ?
La fin du collectif
Authors: Kieffer Morgane 
Published: October 2024

Résumé
Cet article interroge la manière dont trois récits français contemporains, Propriété privée, de Julia Deck (Minuit, 2019), Les États et empires du Lotissement Grand Siècle de Fanny Taillandier (PUF, 2016), et Fabrication de la guerre civile, de Charles Robinson (Seuil, 2016), travaillent le motif de l’Apocalypse en l’ancrant dans une réflexion aux accents ethnologiques et sociologiques autour des territoires périurbains : cités de banlieue et banlieues résidentielles. Dans ces trois textes, à partir d’espaces pourtant bien différents, se développent des hantises partagées : la destruction des modes de vie collectifs comme du sens de la communauté, le repli sur les intérêts individuels dans une perspective du tous contre tous, jusqu’à l’explosion finale, littérale et métaphorique. Si le monde court à sa fin, c’est en banlieue que celle-ci couve.
Denatured Nature
Authors: Scharm Heike 
Published: October 2024

Abstract
This essay places the narrative of the Spanish writer José A. Cano (b. 1954 in Madrid) within the context of contemporary Spanish ecofiction. Concerned with the state of global humanity, Cano reflects a growing postnational perspective among Spanish writers whose works critically address the challenges of the Anthropocene—in particular, the destructive effects the tenets of Western modernity (Kantian ethics, utilitarian values, human-Nature divide, logic of exploitation, dualistic and anthropocentric thought, etc.) have had on the more-than-human world. Heavily influenced by the Romanian philosopher E. M. Cioran, Cano’s novel La felicidad del Malvado (2023) offers a pessimistic outlook regarding the future of humankind. Miguel de Cervantes’s Don Quixote provides another backdrop for this transatlantic novel, situated between the United States and Madrid, allowing Cervantine humor to balance out Cioran’s omnipresent voice of doom.
O “viaduto da controvérsia” em Tucupi: uma reflexão sobre responsabilidade e transparência na administração pública
Authors: Numao Fábio Hideo , Souza João Victor Levinthal Oliveira , Oliveira Luciano Simões , Mendes Luiz Henrique Pereira , Ribeiro Maria Angélica de Jesus 
Published: October 2024

Informamos que as notas de ensino dos casos possuem acesso restrito e são exclusivas para docentes e instrutores vinculados à uma instituição acadêmica. Saiba mais.
Value-Positivity for Matrix Games
Authors: Chatterjee Krishnendu , Oliu-Barton Miquel , Saona Raimundo 
Published: October 2024

Matrix games are the most basic model in game theory, and yet robustness with respect to small perturbations of the matrix entries is not fully understood. In this paper, we introduce value positivity and uniform value positivity, two properties that refine the notion of optimality in the context of polynomially perturbed matrix games. The first concept captures how the value depends on the perturbation parameter, and the second consists of the existence of a fixed strategy that guarantees the value of the unperturbed matrix game for every sufficiently small positive parameter. We provide polynomial-time algorithms to check whether a polynomially perturbed matrix game satisfies these properties. We further provide the functional form for a parameterized optimal strategy and the value function. Finally, we translate our results to linear programming and stochastic games, where value positivity is related to the existence of robust solutions. Funding: This research was supported by Fondation CFM pour la Recherche, the H2020 European Research Council [Grant ERC-CoG-863818 (ForM-SMArt)], the Austrian Science Fund [Grant 10.55776/COE12], ANID Chile [Grant ACT210005], and Agence Nationale de la Recherche [Grant ANR-21-CE40-0020].
Stochastic Control Problems with State Reflections Arising from Relaxed Benchmark Tracking
Authors: Bo Lijun , Huang Yijie , Yu Xiang 
Published: October 2024

This paper studies stochastic control problems motivated by optimal consumption with wealth benchmark tracking. The benchmark process is modeled by a combination of a geometric Brownian motion and a running maximum process, indicating its increasing trend in the long run. We consider a relaxed tracking formulation such that the wealth compensated by the injected capital always dominates the benchmark process. The stochastic control problem is to maximize the expected utility of consumption deducted by the cost of the capital injection under the dynamic floor constraint. By introducing two auxiliary state processes with reflections, an equivalent auxiliary control problem is formulated and studied, which leads to the Hamilton-Jacobi-Bellman equation with two Neumann boundary conditions. We establish the existence of a unique classical solution to the dual partial differential equation using some novel probabilistic representations involving the local time of some dual processes together with a tailor-made decomposition-homogenization technique. The proof of the verification theorem on the optimal feedback control can be carried out by some stochastic flow analysis and technical estimations of the optimal control. Funding: L. Bo and Y. Huang are supported by the National Natural Science Foundation of China [Grant 12471451], the Natural Science Basic Research Program of Shaanxi [Grant 2023-JC-JQ-05], the Shaanxi Fundamental Science Research Project for Mathematics and Physics [Grant 23JSZ010], and Fundamental Research Funds for the Central Universities [Grant 20199235177]. X. Yu is supported by the Hong Kong RGC General Research Fund (GRF) [Grant 15304122] and the Research Centre for Quantitative Finance at the Hong Kong Polytechnic University [Grant P0042708].
Posterior tooth anatomy: wax carving. Part 1
Authors: Mackenzie Louis 
Published: October 2024

This series describes step-by-step wax carving guides, developed over a 14-year period, to teach three dimensional tooth anatomy to undergraduate students at the University of Birmingham's school of dentistry. The carving sequences have also been extensively used in postgraduate training courses, designed to help experienced clinicians master dental anatomy for practical application in restorative procedures. CPD/Clinical Relevance: Knowledge and understanding of posterior tooth anatomy is a key skill in dentistry.
Pre- and postoperative Coronal Plane Alignment of the Knee classification and its impact on clinical outcomes in total knee arthroplasty
Authors: Konishi Toshiki , Hamai Satoshi , Tsushima Hidetoshi , Kawahara Shinya , Akasaki Yukio , Yamate Satoshi , Ayukawa Shuhei , Nakashima Yasuharu 
Published: October 2024

AimsThe Coronal Plane Alignment of the Knee (CPAK) classification has been developed to predict individual variations in inherent knee alignment. The impact of preoperative and postoperative CPAK classification phenotype on the postoperative clinical outcomes of total knee arthroplasty (TKA) remains elusive. This study aimed to examine the effect of postoperative CPAK classification phenotypes (I to IX), and their pre- to postoperative changes on patient-reported outcome measures (PROMs).MethodsA questionnaire was administered to 340 patients (422 knees) who underwent primary TKA for osteoarthritis (OA) between September 2013 and June 2019. A total of 231 patients (284 knees) responded. The ­Knee Society Score 2011 (KSS 2011), Knee injury and Osteoarthritis Outcome Score-12 (KOOS-12), and Forgotten Joint Score-12 (FJS-12) were used to assess clinical outcomes. Using preoperative and postoperative anteroposterior full-leg radiographs, the arithmetic hip-knee-ankle angle (aHKA) and joint line obliquity (JLO) were calculated and classified based on the CPAK classification. To investigate the impact on PROMs, multivariable regression analyses using stepwise selection were conducted, considering factors such as age at surgery, time since surgery, BMI, sex, implant use, postoperative aHKA classification, JLO classification, and changes in aHKA and JLO classifications from preoperative to postoperative.ResultsThe preoperative and postoperative CPAK classifications were predominantly phenotype I (155 knees; 55%) and phenotype V (73 knees; 26%), respectively. The change in the preoperative to postoperative aHKA classification was a significant negative predictive factor for KOOS-12 and FJS-12, while postoperative apex proximal JLO was a significant negative predictive factor for KSS 2011 and KOOS-12.ConclusionIn primary TKA for OA, preoperative and postoperative CPAK phenotypes were associated with PROMs. Alteration in varus/valgus alignment from preoperative to postoperative was recognized as a negative predictive factor for both KOOS-12 and FJS-12. Moreover, the postoperative apex proximal JLO was identified as a negative factor for KSS 2011 and KOOS-12. Determining the target alignment for each preoperative phenotype with reproducibility could improve PROMs.Cite this article: Bone Joint J 2024;106-B(10):1059–1066.
Predicting recurrence of instability after a primary traumatic anterior shoulder dislocation
Authors: Makaram Navnit S. , Becher Hannes , Oag Erlend , Heinz Nicholas R. , McCann Conor J. , Mackenzie Samuel P. , Robinson C. M. 
Published: October 2024

AimsThe risk factors for recurrent instability (RI) following a primary traumatic anterior shoulder dislocation (PTASD) remain unclear. In this study, we aimed to determine the rate of RI in a large cohort of patients managed nonoperatively after PTASD and to develop a clinical prediction model.MethodsA total of 1,293 patients with PTASD managed nonoperatively were identified from a trauma database (mean age 23.3 years (15 to 35); 14.3% female). We assessed the prevalence of RI, and used multivariate regression modelling to evaluate which demographic- and injury-related factors were independently predictive for its occurrence.ResultsThe overall rate of RI at a mean follow-up of 34.4 months (SD 47.0) was 62.8% (n = 812), with 81.0% (n = 658) experiencing their first recurrence within two years of PTASD. The median time for recurrence was 9.8 months (IQR 3.9 to 19.4). Independent predictors increasing risk of RI included male sex (p < 0.001), younger age at PTASD (p < 0.001), participation in contact sport (p < 0.001), and the presence of a bony Bankart (BB) lesion (p = 0.028). Greater tuberosity fracture (GTF) was protective (p < 0.001). However, the discriminative ability of the resulting predictive model for two-year risk of RI was poor (area under the curve (AUC) 0.672). A subset analysis excluding identifiable radiological predictors of BB and GTF worsened the predictive ability (AUC 0.646).ConclusionThis study clarifies the prevalence and risk factors for RI following PTASD in a large, unselected patient cohort. Although these data permitted the development of a predictive tool for RI, its discriminative ability was poor. Predicting RI remains challenging, and as-yet-undetermined risk factors may be important in determining the risk.Cite this article: Bone Joint J 2024;106-B(10):1111–1117.
Characterization of articular lesions associated with glenohumeral instability using arthroscopy
Authors: Luengo-Alonso Gonzalo , Valencia Maria , Martinez-Catalan Natalia , Delgado Cristina , Calvo Emilio 
Published: October 2024

AimsThe prevalence of osteoarthritis (OA) associated with instability of the shoulder ranges between 4% and 60%. Articular cartilage is, however, routinely assessed in these patients using radiographs or scans (2D or 3D), with little opportunity to record early signs of cartilage damage. The aim of this study was to assess the prevalence and localization of chondral lesions and synovial damage in patients undergoing arthroscopic surgery for instablility of the shoulder, in order to classify them and to identify risk factors for the development of glenohumeral OA.MethodsA total of 140 shoulders in 140 patients with a mean age of 28.5 years (15 to 55), who underwent arthroscopic treatment for recurrent glenohumeral instability, were included. The prevalence and distribution of chondral lesions and synovial damage were analyzed and graded into stages according to the division of the humeral head and glenoid into quadrants. The following factors that might affect the prevalence and severity of chondral damage were recorded: sex, dominance, age, age at the time of the first dislocation, number of dislocations, time between the first dislocation and surgery, preoperative sporting activity, Beighton score, type of instability, and joint laxity.ResultsA total of 133 patients (95%) had synovial or chondral lesions. At the time of surgery, shoulders were graded as having mild, moderate, and severe OA in 55 (39.2%), 72 (51.4%), and six (4.2%) patients, respectively. A Hill-Sachs lesion and fibrillation affecting the anteroinferior glenoid cartilage were the most common findings. There was a significant positive correlation between the the severity of the development of glenohumeral OA and the patient’s age, their age at the time of the first dislocation, and the number of dislocations (p = 0.004, p = 0.011, and p = 0.031, respectively).ConclusionSynovial inflammation and chondral damage associated with instability of the shoulder are more prevalent than previously reported. The classification using quadrants gives surgeons more information about the chondral damage, and could explain the pattern of development of glenohumeral OA after stabilization of the shoulder. As the number of dislocations showed a positive correlation with the development of OA, this might be an argument for early stabilization.Cite this article: Bone Joint J 2024;106-B(10):1125–1132.
Preoperative patient-reported outcome measures predict minimal clinically important difference and patient-acceptable symptomatic state following arthroscopic Bankart repair
Authors: Long Yi , Zheng Zhen-Ze , Li Xin-Hao , Cui De-Dong , Deng Xing-Hao , Guo Jiang , Yang Rui 
Published: October 2024

AimsThe aims of this study were to validate the minimal clinically important difference (MCID) and patient-acceptable symptom state (PASS) thresholds for Western Ontario Shoulder Instability Index (WOSI), Rowe score, American Shoulder and Elbow Surgeons (ASES), and visual analogue scale (VAS) scores following arthroscopic Bankart repair, and to identify preoperative threshold values of these scores that could predict the achievement of MCID and PASS.MethodsA retrospective review was conducted on 131 consecutive patients with anterior shoulder instability who underwent arthroscopic Bankart repair between January 2020 and January 2023. Inclusion criteria required at least one episode of shoulder instability and a minimum follow-up period of 12 months. Preoperative and one-year postoperative scores were assessed. MCID and PASS were estimated using distribution-based and anchor-based methods, respectively. Receiver operating characteristic curve analysis determined preoperative patient-reported outcome measure thresholds predictive of achieving MCID and PASS.ResultsMCID thresholds were determined as 169.6, 6.8, 7.2, and 1.1 for WOSI, Rowe, ASES, and VAS, respectively. PASS thresholds were calculated as ≤ 480, ≥ 80, ≥ 87, and ≤ 1 for WOSI, Rowe, ASES, and VAS, respectively. Preoperative thresholds of ≥ 760 (WOSI) and ≤ 50 (Rowe) predicted achieving MCID for WOSI score (p < 0.001). Preoperative thresholds of ≤ 60 (ASES) and ≥ 2 (VAS) predicted achieving MCID for VAS score (p < 0.001). A preoperative threshold of ≥ 40 (Rowe) predicted achieving PASS for Rowe score (p = 0.005). Preoperative thresholds of ≥ 50 (ASES; p = 0.002) and ≤ 2 (VAS; p < 0.001) predicted achieving PASS for the ASES score. Preoperative thresholds of ≥ 43 (ASES; p = 0.046) and ≤ 4 (VAS; p = 0.024) predicted achieving PASS for the VAS.ConclusionThis study defined MCID and PASS values for WOSI, Rowe, ASES, and VAS scores in patients undergoing arthroscopic Bankart repair. Higher preoperative functional scores may reduce the likelihood of achieving MCID but increase the likelihood of achieving the PASS. These findings provide valuable guidance for surgeons to counsel patients realistically regarding their expectations.Cite this article: Bone Joint J 2024;106-B(10):1118–1124.