bluuebunny/crossref_metadata_2025_split huggingface dataset:
Young Women’s Political Participation and Gender Depoliticization in Nigeria
Authors: Adebajo Adeola Aderayo , Yusirat Owolola Oluwakemi , Abraham Adebajo Olatomiwa , Seun Adebajo Adesola 
Published: October 2024

Since return to Nigeria to civilian administration in 1999, women have been making efforts to access political leadership space with little progress. With international and national instruments to ensure more women gain inroad into politics, there is a dismal record in this aspect. Anchoring the paper on theory of political participation, the paper explored the possibility of gender depoliticisation through the involvement of young women in politics. Desk research method which utilised secondary sources of data collection was employed. The paper argued that in spite of the fact that young women are involved in activism,they are grossly underrepresented in political leadership. Culture, political acrimony, stigmatisation, religion, lack of finance, political violence, etc., constitute barriers to young women representation in politics. The paper contended that there is always political inequality between women and men, particularly among the youngest generations. The paper concluded that young women are at risk of not being included and favourably considered in the decision making process, as non-participation in politics poses a threat to their gender's dignified existence in the body polity. It recommended that socio-economic barriers including culture, religion, patriarchal belief, political acrimony, insecurity, etc., should be addressed. Empowerment should start from the family to re-orientate on the social barriers affecting young women participation in leadership positions. Girl-child education needs prioritisation to develop potentials, particularly contribution in decision making process at all levels of governance, among others.
A rare case report of hurthle cell adenoma mimicking malignancy
Authors: Hiremani Shashikala Gurappa 
Published: October 2024

Thyroid lesions are the most common endocrine diseases, occurring in usually all age groups, though accurate diagnosis still remains a challenge, as due to oncocytic potentials of Thyroid cells leads to like indeterminate or suspicious diagnosis. Long standing benign Thyroid lesion shows atypical presentation suspicious to malignancy. Now a days with the help of WHO classification and available advanced diagnostic measures helping to confirm the diagnosis, avoiding overdiagnosis and wrong treatment. Hence this study review the importance of Histopathological study with coordination with immunohistochemistry (IHC) study, where suspicious thyroid malignant lesion finally diagnosed as benign Hurthle cell/ Oncocytic adenoma in Nodular Goitre.: 72 year old female presented huge neck swelling since one year, was reviewed in our departments of Pathology and ENT. Fine needle aspiration cytology (FNAC) features are suspicious of Malignancy, further Histopathological features were studied with co ordance of IHC study. FNAC features, which were suspicious of Malignancy were further studied with Histopathological and IHC studies diagnosed as Hurthle cell/ Oncocytic adenoma in Nodular Goitre. Histopathology remains the cornerstone for the diagnosis of thyroid oncocytic lesions and also in distinguishing between adenoma and carcinoma.
Subchronic Toxicity of Ethanol Extract of Mangosteen Rind (Garcinia Mangostana L.) on Kidney Function in Wistar Rats
Authors: Ratwita Welly , Afgani Apen , Sovia Evi , Pradini Astri , Hartaki Mochamad Taufik Putra 
Published: October 2024

Mangosteen (Garcinia mangostana L.) is a fruit that possesses antioxidant, antibacterial, antihistamine, anti-inflammatory, and antidiabetic properties. Before this, an acute toxicity test was conducted on the ethanol extract of mangosteen rind. However, further testing is required, specifically the subchronic toxicity test, to identify any hazardous effects that may not have been found in the previous study. The objective of this study is to evaluate the amount of toxicity based on the mortality rate, alterations in the relative weight of the kidneys, and changes in renal function as shown by levels of urea and creatinine. This study is an experimental investigation that employs the Post-test Only Control Group Design methodology, with a sample of 40 rats. The rats were categorized into two groups: the control group and the treatment group. The treatment group was divided into three subgroups, each receiving a dosage of 250 mg/kg body weight. The doses were 500 milligrams per kilogram and 1000 milligrams per kilogram of body weight, respectively. The control group received simply water and feed. The duration of the treatment was 28 days. Observations were conducted over 28 days, which involved monitoring animal mortality. On the 29th day, a surgical procedure was carried out to assess the comparative weight of the kidneys and collect blood samples for analyzing the levels of urea and creatinine. The findings demonstrated no mortality in the test subjects, although there was an elevation in the relative mass of the kidneys and an increase in urea concentrations. The increase in urea levels was observed in female rats using the Kruskal–Wallis test (P = 0.019). The study was further conducted using the post-hoc Mann–Whitney test. Control female rats exhibited notable disparities when administered dosages of 250 mg/kgBW and 500 mg/kgBW. The repeated administration of an ethanolic extract derived from the peel of the mangosteen fruit had a detrimental impact on the functioning of the kidneys, as evidenced by a rise in urea concentrations.
Keywords: mangosteen, toxicity test, subchronic, kidney
Cenas afetadas pela (minha) branquitude na formação de professores
Authors: Silva Costa Campos Daniela 
Published: October 2024

Na presente pesquisa são (re)veladas cenas de um campus universitário situado no interior do norte do Brasil, no qual atuava como professora de Psicologia para as licenciaturas. Ao tomar o afeto como condutor dessa travessia revela-se que o campo da formação de professores é constituído pelo entrelaçamento dos corpos de estudantes, professores, gestores e demais colaboradores, assim como pelo entrelaçamento desses corpos em determinado tempo e espaço. A análise das cenas expõe a racialização e a branquitude no cerne dos processos de subjetivação e sociabilidade no escopo da civilização ocidentalizada, assim como em minha própria atuação. Nesse sentido, a contribuição da Psicologia deve estar necessariamente atrelada aos modos de relacionalidade ampliados – às questões éticas – assim como às questões estéticas que enceram a concepção de performance.
Mariana Luz e "A mendiga do Amor" na sociedade patriarcal
Authors: Silva Mirna Rocha , Tolomei Cristiane Navarrete 
Published: October 2024

O gênero, enquanto diferença sexual, é a representação do sujeito feminino que tem servido de suporte nas construções sociais da humanidade, sobretudo em sociedades colonizadas, nas quais as mulheres vêm sendo limitadas pelo patriarcado. Nesse sentido, este texto analisa o poema “A mendiga do amor”, de 1896, da escritora maranhense Mariana Luz, verificando como ela evidência as marcas do patriarcado impressas nos versos em relação à condição da mulher na sociedade brasileira no final do século XIX. Para isso, observa-se, em um primeiro momento, de que modo a poesia luziana pode ser tomada como de resistência, uma vez que transforma a literatura como instrumento de análise social; e, em segundo momento, analisa-se a colonialidade de gênero sofrida pelo sujeito feminino do poema na sociedade patriarcal brasileira, em especial, maranhense. Realizou-se, então, uma pesquisa exploratória e descritiva, documental e bibliográfica que teve como principais referenciais teóricos dos estudos decoloniais, Aníbal Quijano (2005), Walter Mignolo (2007; 2021), Lélia Gonzalez (2018), Maria Lugones (2014; 2020), entre outros; sobre o patriarcado, Heleieth Saffioti (1987; 2004) e Carole Pateman (1993); e, acerca da vida e da obra de Mariana Luz, Jucey Santana (2014), José Neres (2018), Cristiane Tolomei (2019) e Gabriela Santana (2021). Diante disso, verificou-se que Mariana Luz teve um perfil decolonial ao contrapor-se aos diversos paradigmas eurocentrados da sociedade brasileira da época, e denunciou por meio dos seus versos às opressões submetidas pelo sujeito feminino pelo sistema patriarcal do país.
Digitalisasi Sastra Kontemporer Lewat Grafik Novel “Tabi” Karya Marchella FP
Authors: Liana Patricia 
Published: October 2024

The digitization of literature is one of the effects of the postmodern era that cannot be avoided. This literaturebased qualitative research investigates the development of postmodernism in literature, with a primary emphasis on its principles and implications in modern literature. This research aims to find out how postmodernism, especially in the digital era, has an impact on the recognition and sales of modern literary works. Using Marchella FP's novel "Tabi", which was released as a case study in October 2023, this study investigates the role of social media platforms, especially TikTok, in promoting and selling literature. This research emphasizes the important implications of digital postmodernism for future prospects by emphasizing paradigm shifts and enhanced inclusivity in the digital world. Additionally, this research examines the idea of viral marketing and how it relates to spreading literary works through social media platforms such as TikTok. Keywords: Contemporary Literature, Literary Digitization, Postmodernism.
Analysis and Implementation of Metamaterial-Inspired Microstrip Antenna for Wireless Applications
Authors: Pande S. V. , Patil D. P. , Sangole M. K. , Antonov S. 
Published: October 2024

In this paper, a novel metamaterial-inspired microstrip antenna for wireless applications is proposed. The proposed design consists of a radiating path on top and a uniformly distributed split ring-shaped metamaterial structure on the ground. The presented antenna of 50´38 mm with a thickness of 1.6 mm is printed on FR4 substrate and resonates at 1.80 GHz. The design was fabricated and the measured results were found to be in accordance with the simulations. The goal is accomplished by loading uniformly distributed split ring-shaped metamaterial structures on the ground plane of this antenna. The results of the experiments show that using the metamaterial structure on the ground plane improved gain from 4.34 to 7.3 dB, efficiency from 5.94 to 7.8 dB compared to the conventional patch antenna. This introduction in the ground plane exhibits return loss up to –38 dB and modified the gain and directivity to 7.3 and 7.8 dB respectively. The presented antenna has 45 MHz bandwidth. The presented design is proven by simulated surface current, S parameter, VSWR, radiation pattern. We have also investigated the effect of substrate permittivity, split width, and inter-element spacing in a split ring-shaped metamaterial structure on return loss. This directive antenna is designed for the applications of wireless local area networks and other Internet of things-based applications.
A Gender-Based Approach to Cardiovascular Disease Risk Factors among Adults with Diabetes Mellitus
Authors: Abdul Raheem Yousif , Yacoub Selwa Elias , Akram Wijdan 
Published: October 2024

بالرغم من الحقيقة التي تفضي إن المرأة تواجه خطرا اقل من الرجل فيما يخص إصابتها بإمراض القلب والأوعية الدموية والوفيات الناجمة عنها قبل سن اليأس , فإنها تواجه نفس الخطورة او أعلى في حالة إصابتها بداء السكري
لمقارنة الفرو قات مابين الجنسين فيما يخص عوامل الخطورة لأمراض القلب والأوعية الدموية لدى البالغين المصابين بمرض السكري والمرضى الغير مصابين به
دراسة حالة مع مجموعة ضابطة. أجريت الدراسة في المركز التخصصي لأمراض الغدد الصم والسكري وفي عيادة الباطنية / العيادة الخارجية لمستشفى الكندي التعليمي للفترة من كانون الثاني ولغاية كانون الأول 2008.
اختيرت عينة من 314 (152 ذكور و 136 إناث ) من المرضى المصابين بداء السكري و 136( 72 ذكور و 64 إناث ) من المرضى الغير مصابين بداء السكري كمجموعة ضابطة . مجموعتي الدراسة تم اختيارهم من اللذين تتراوح أعمارهم مابين 18 – 35 سنة
تم التقصي عن عوامل الخطورة لأمراض القلب والأوعية الدموية لدى جميع المشمولين بالدراسة والتي تضمنت , تاريخ العائلة , التدخين , النشاط البدني , مؤشر كتلة الجسم , البدانة المركزية , ارتفاع ضغط الدم , ارتفاع نسبة الكولسترول في الدم , ارتفاع نسبة الدهون في الدم , انعدام ضبط نسبة السكر في الدم .
بعدها تمت دراسة الفرو قات مابين الجنسين فيم يخص عوامل الخطورة لدى المصابين بداء السكري وغير المصابين.
أظهرت الدراسة وجود فروقات إحصائية معنوية مابين الجنسين فيما يتعلق بعوامل الخطورة للإصابة بإمراض القلب والأوعية الدموية ( ارتفاع ضغط الدم , ارتفاع نسبة الكولسترول في الدم , ارتفاع نسبة الدهون في الدم , التدخين , النشاط البدني ) للمرضى الغير مصابين بداء السكري في حين تضاءلت هذه الفرو قات لدى المرضى الغير مصابين بداء السكري لجميع عوامل الخطورة فيما عدا عاملي التدخين والنشاط البدني .
تزداد عواقب عوامل الخطورة لإمراض القلب والأوعية الدموية عند الإصابة بداء السكري لدى الإناث مما هي عليه لدى الذكور وما قد ينجم عنها من مخاطر الإصابة بأمراض القلب ذات العلاقة بمرض السكري.
Spectrophotometric determination of salbutamol sulphate in bulk and in pharmaceutical formulations
Authors: Salman Maha Kadhim 
Published: October 2024

طُوّرتْ طريقة لونية جديدة بسيطة وحسّاسة لتعيين تركيز السالبيتمول في المادة النقية وفي بعض المستحضرات الصيدلانية إنّ تعتمد الطريقةَ على الحصول على لون لصبغة الازو الصفراء عند طول موجي 447 نانومتر والمتكونة مِن ْازدواج السالبيتمول مع ملح الديازونيوم ل 2و4- ثنائي كلورو أنيلين, قانون بير وجد مطاعاَ في مدى تركيزَ20-2.5 ملغم/لتر مع ظهور مدى لقيم الامتصاصية المولارية بين(4000-7265) لتر/مول.سم.وقد قدرت الظروف المثلى للتفاعل وكذلك العوامل التحليلية الأخرى.
New Deletion of Multiple Genes in the Pathogenic Subtelomeric Region is Related to the Phenotypic Heterogeneity of Patients with Polymalformation Syndrome
Authors: Yepes-Madrid Nathalie , Bernal David Posada- , Giraldo Lina Johanna Moreno- 
Published: October 2024

Abstract

Introduction:
Genomic testing has advanced significantly, enabling the identification of changes ranging from specific locus modifications to genomic structural alterations. This has improved the diagnosis of diseases and the understanding of little-known genetic disorders.
Objective:
To describe the case of an adolescent with no consanguineous parents and no family history of genetic variants but with cognitive-behavioral impairment, epilepsy, hypothyroidism, tall stature, and minor facial dysmorphisms suggestive of an overgrowth syndrome. Due to the complexity of the patient's phenotype affecting multiple organs and systems, the patient underwent aCGH analysis to identify deletions or duplications.
Methods:
Genomic DNA was extracted from a peripheral blood sample of the patient. The DNA was labeled and hybridized using the Agilent® SurePrint G3 Human CGH array 4x180K. The data were scanned and analyzed with the Agilent CytoGenomics v5® software.
Results:
The aCGH analysis identified a sub-telomeric pathogenic heterozygous deletion in the chromosomal region 5q35.2q35.3. A search was conducted in the Online Mendelian Inheritance in Man, Clinical Genome Resource, and GeneScout databases, where 12 out of 74 genes were associated with medical conditions. Of these, 9 had autosomal recessive inheritance mechanisms and the remaining 3 had autosomal dominant (AD) inheritance. For genes with AD and unclear inheritance mechanisms, and with a high risk of genotype/phenotype correlation (reversed phenotype, crucial for precise diagnosis), a Human Phenotype Ontology search was conducted. This search related the deletion to conditions such as hematological malignancy predisposition syndrome, hereditary angioedema, infantile hypercalcemia 2, Fanconi renotubular syndrome 2, nephrolithiasis/hypophosphatemic osteoporosis 1, Lewy body dementia, and Sotos syndrome. This deletion is associated with a complex phenotype, including autism spectrum disorder and several physical anomalies.
Conclusions:
Genetic tests such as aCGH are fundamental for diagnosing congenital anomalies and neurodevelopmental disorders. Identifying deletions in the 5q35 region enhances the understanding of polymalformative syndromes and facilitates genetic counseling, thereby improving prognosis and family planning for patients.
The Role of Thoracic Ultrasound in a Rare Combination of Lung Abscess and Congenital Pulmonary Airway Malformation (CPAM): Case Report and Literature Review
Authors: Amendolea Antonella , Gaeta Giovanni , Avino Gabriele 
Published: October 2024

Abstract

Background
Congenital Pulmonary Airway Malformation (CPAM) is a rare congenital lung abnormality characterized by cystic lesions. Diagnosis is often made prenatally via ultrasound or postnatally through thoracic imaging.
Case presentation:
A two-year-old girl presented with fever, rhinitis, asthenia, and hypoalimentation. Initial antibiotic therapy did not resolve her symptoms. Laboratory tests showed elevated CRP, neutrophilic leukocytosis, anemia, and thrombocytosis. Suspecting Kawasaki disease, intravenous immunoglobulins and acetylsalicylic acid were administered, but fever recurred. Thoracic ultrasound revealed a 5.5 cm anechoic formation with hyperechoic spots, indicative of a lung abscess within CPAM. Chest radiography confirmed a posterior basal opacity with coarse air-fluid levels. The patient was transferred to a regional center for further management, where the diagnosis was confirmed, and surgical intervention was planned.
Conclusions
Thoracic ultrasound plays a crucial role in the diagnosis and management of CPAM, particularly when complicated by infections such as lung abscesses. Early and accurate diagnosis can significantly improve patient outcomes, as demonstrated in this case report.
MaxEnt Machine Learning Technique based Assessment of Landslide Susceptibility of West Nayar Basin (Garhwal Himalaya), Uttarakhand, India
Authors: KUMAR AJAY , Pandey Arvind , Kumar Atul 
Published: October 2024

Abstract

Landslide susceptibility prediction mapping plays an imperative role in hazard mitigation by prioritizing areas for intervention and implementing effective risk reduction measures, thereby safeguarding communities and infrastructure. In this current assessment, 121 landslide occurrences and eight landslide-conditioning parameters were considered to develop a landslide susceptibility model for the West Nayar Basin (WNB), Uttarakhand, India. The Maximum Entropy multivariate statistical model (MaxEnt) was applied to calibrate and assess landslide susceptibility. The ensemble model data reveal that 2.69% and 7.31% of the WNB area are classified as very highly and highly susceptible to landslides, respectively. Meanwhile, around 65% of the basin is designated as a safe zone with a lower risk of landslides, and 25% of the area is identified as having a moderate probability of landslide risk. The major and frequent occurrence of landslides in the WNB is linked to low to middle elevations, proximity to rivers, and motorable roads. Consequently, the resulting model and observed patterns highlight the major variables that cause landslides and their corresponding significance. This modeling approach provides baseline data at a regional scale, which can enhance economic development planning in the WNB by informing better land use and watershed management practices. Integrating such models into planning processes ensures more resilient infrastructure and communities, promoting sustainable development in landslide-prone areas.
Alterations of the gut virome in patients with Parkinson's disease
Authors: zhang wei , Wang Xiaoting , Guo Ruochun , Xing Guorui , Xu Dandan , Ma Xiaoyan , Chen Qiang , Li Shenghui , Qin Yi , Liu Jinping , Zhong Xueyan , Hu Xihong , Hu Xiaohui , Zheng Wenxu , Hu Zengchun , Yan Qiulong 
Published: October 2024

Abstract

Parkinson's disease (PD) ranks as the second most prevalent neurodegenerative disorder, following Alzheimer's disease, and it has a significant link to the gut bacteriome. However, the relationship between PD and gut virome is unclear. To explore the gut virome's traits in PD, we analyzed the gut viral communities of 89 PD patients and 89 healthy individuals, utilizing metagenome-wide analysis of fecal metagenomes from two accessible public datasets. Our findings indicate that PD patients exhibit a marked increase in gut viral richness and diversity, alongside significant shifts in the overall viral composition. At the family level, PD patients showed elevated levels of Siphoviridae, Myoviridae, p-crAss-like, Podoviridae, Salasmaviridae, Circoviridae, and Herelleviridae, coupled with a reduced presence of Quimbyviridae. We identified 640 vOTUs that were differentially abundant between patients and controls, including a notable increase in Siphoviridae and Myoviridae viruses in PD patients. Interestingly, PD-enriched vOTUs predominantly infected a diverse array of bacterial hosts, including but not limited to Alistipes, Lawsonibacter, Oscillibacter, Faecalibacterium, Ruthenibacterium, Intestinimonas, Flavonifractor and Fournierella. Conversely, the major hosts for the HS-enriched vOTUs were primarily Bacteroides and Prevotella species. Additionally, certain viral functional orthologs, such as thymidylate synthase (K00560) and integrases (K14059), exhibited significant differences in prevalence between PD-enriched and HS-enriched vOTUs, highlighting the potential functional impact of these PD-associated viruses. Moreover, we developed classification models using gut viral signatures to distinguish PD patients from healthy subjects, achieving an optimal area under the receiver operator characteristic curve (AUC) of up to 0.854. The models also demonstrated high accuracy in predicting independent samples. This underscores the gut virome's clinical potential as a diagnostic tool for PD. This study pinpointed viral signatures that distinguish significantly between Parkinson's Disease (PD) patients and healthy subjects (HS), and showed that these distinctive viral markers hold promise as novel targets for PD intervention. This study lays a foundation for future research into the mechanisms and treatment strategies of this and potentially other autoimmune diseases.