bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prosthetic Rehabilitation of Continuous Maxillary and Orbital Defect
Authors: Kumar Yogesh , Bharate Vinayak , Babu Dinesh , Verma Chandralekha 
Published: July 2017

ABSTRACT
Orbital exenteration along with hemimaxillectomy for malignant tumor of maxilla usually results in continuous orbital and maxillary defect. A removable maxillofacial prosthesis with adequate retention and stability during functional movement along with good esthetics is the key for successful rehabilitation of such patients. This case report describes a novel and yet cost-effective method for retention of silicone orbital prosthesis using acrylic resin base attached to maxillary obturator using pin and socket of an electric plug which results in better retention of both the prosthesis.

How to cite this article
Kumar Y, Bharate V, Babu D, Verma C. Prosthetic Rehabilitation of Continuous Maxillary and Orbital Defect. Int J Prosthodont Restor Dent 2017;7(2):77-80.
Time to say Farewell
Authors: Lloyd Margaret 
Published: July 2017

<p>The Journal of Learning Design is about to close. Our last issue was Volume 10 (2) released in March 2017.</p><p>In closing and saying farewell, we would like to sincerely thank those who have written, reviewed, read and referenced the articles we have published in our 27 issues (10 volumes). Thanks must also go to the Queensland University of Technology for encouraging and supporting the journal, particularly since our move to an OJS platform.</p><p>The Journal has built a reputation for quality and diversity of approach – we have covered a wide range of disciplines and learning technologies in accessible ways. We have supported the cause of Open Access publishing and shown how being ‘open’ and ‘free’ need not compromise rigour. We have supported the cause of online publishing and shown it to be a viable alternative that does not take advantage of anyone or treat creative output as a commercial commodity.</p><p>Above all, we have collectively supported the promotion of the scholarship of teaching and learning in higher education. We believe we have also filled an important role to support early career academics and emerging researchers. We have learnt a great deal as editors and are grateful for the opportunities the journal has presented to us both personally and professionally.</p><p>There is no sadness in closing the journal. It is simply time to say Goodbye with good grace and in the knowledge of a job well done. Thank you to all.</p><p><strong> </strong></p><p><strong>Margaret Lloyd</strong>, Queensland University of Technology, Australia<strong></strong></p><p><strong>Nan Bahr, </strong>Griffith University, Australia</p><p><strong> </strong></p><p><strong> </strong></p><p class="JLDReferences"> </p>
O EFEITO DAS DICAS NA APRENDIZAGEM DO FOREHAND PARA CRIANÇAS COM CARACTERÍSTICAS DE DÉFICIT DE ATENÇÃO
Authors: Brusamolin Boell Isabelle , Yoshie Silva Yamaguchi Andréa , Ladewig Iverson , Hernandes Spinelli Adilson , Gustavo Cangussú Franz Luiz 
Published: July 2017

O objetivo do estudo foi verificar a eficácia das dicas de aprendizagem no trabalho com crianças, com características de desatenção. Participaram 45 crianças, entre 7 e 11 anos, com e sem características de desatenção. O tratamento estatístico foi realizado por testes não-paramétricos e a análise descritiva por mediana e desvio padrão. As crianças com TDAH que não receberam as dicas obtiveram a pior performance entre os grupos, enquanto as crianças sem TDAH que receberam as dicas tiveram a melhor performance. Entretanto, crianças com TDAH que receberam dicas obtiveram uma performance similar às crianças sem TDAH que receberam dicas. Os resultados obtidos pelas crianças com TDAH, demonstraram a eficácia das dicas de aprendizagem com crianças com características de desatenção.
Renal Toxicity in Patients Treated with Anti-Pd-1 Targeted Agents for Solid Tumors
Authors: Iacovelli Roberto , Ciccarese Chiara , Fantinel Emanuela , Bimbatti Davide , Romano Mario , Porcaro Antonio Benito , Siracusano Salvatore , Mazzarotto Renzo , Artibani Walter , Tortora Giampaolo 
Published: July 2017

Aim Immune checkpoint inhibitors of programmed death-1 (PD-1)/programmed death-ligand 1 (PD-L1) have recently entered in the therapeutic armamentarium of several types of cancer. Besides the survival benefit, the true revolution of these agents is the distinctive toxicity profile. We aim to assess the incidence and relative risk (RR) of renal toxicity (RT) in patients with solid tumors treated with monoclonal antibodies (mAbs) directed against PD-1/PD-L1. Methods By searching the MEDLINE/PubMed, Cochrane Library, and ASCO Meeting abstracts, prospective studies were identified. Combined RRs and 95% confidence intervals (CIs) were calculated using fixed- or random-effects methods. Results Eleven articles were selected for this analysis, with a total of 5,722 patients who were used to evaluate RT. The incidence of anti-PD-1-related RT of all-grades and high-grades was low (1.4% and 0.2%, respectively). However, compared to controls, treatment with PD-1 inhibitors was associated with a significant increased risk of any grade RT (RR = 1.85, 95% CI, 1.07-3.20; p = 0.03) but not high-grade RT (RR = 1.57, 95% CI, 0.56-4.36; p = 0.39). Pembrolizumab significantly increased the risk of any-grade RT (RR = 4.91, p = 0.01) compared to the control arm, and a significant difference was found between nivolumab and pembrolizumab for developing RT of any grade (p = 0.04). Conversely, no differences were identified between the type of prior treatment (prior platinum-containing chemotherapy regimen vs. nonplatinum containing regimen). Conclusions Immune-mediated RT is a rare adverse event that is generally low in severity. Compared to standard therapies, anti-PD-1 mAbs significantly increase the risk of any grade, without conditioning the risk of high-grade RT. The type of PD-1 inhibitor could affect the risk of developing any-grade RT, while prior therapy with platinum-containing regimens does not affect the risk of developing RT.
‘Een verdrag met potentieel vérstrekkende gevolgen’
Authors: Pulles G.J.W. 
Published: July 2017

‘Een verdrag met potentieel vérstrekkende gevolgen’: De toepassing van het VN-verdrag Handicap door de Nederlandse rechter
De toetreding van het Koninkrijk der Nederlanden tot het VN-verdrag Handicap zal leiden tot nieuwe rechtsontwikkelingen op het gebied van bescherming van de rechten van personen met een handicap. Een belangrijke rol zal daarbij zijn weggelegd voor de rechter, die immers over de toepassing en interpretatie van het Verdrag zal gaan oordelen in concrete gevallen. De rechter zal daarbij rekening moeten houden met de regels die gelden voor de toepassing van internationaal recht. Dit artikel handelt over de wijzen waarop de rechter het Verdrag kan toepassen en op die manier kan laten doorwerken in de Nederlandse rechtsorde. Het gaat in op de Nederlandse regels voor rechtstreekse, indirecte en horizontale toepassing. Daarbij wordt aandacht besteed aan de uitspraak van 10 oktober 2014 van de Hoge Raad, waarin een hele nieuwe maatstaf voor rechtstreekse toepassing van internationaal recht werd aangelegd. Daarnaast komen de rol en de invloed van Europese rechtspraak van het EHRM en van het HvJ EU en van uitspraken van internationale verdragscomités aan de orde. Het artikel verschaft praktijkjuristen daarmee hopelijk extra argumenten om bij te dragen aan een wezenlijke bescherming van de rechten en waardigheid van personen met een handicap.
De Lex Michiels
Authors: Woldendorp H.E. (Hans Erik) 
Published: July 2017

De Lex Michiels. Handhaving van de asbestregelgeving: met effect en op niveau?
Auteur behandelt in zijn bijdrage de handhaving van de asbestregelgeving. Deze regelgeving behoort volgens de Rekenkamer tot de slechtst nageleefde regelgeving. Auteur gaat vanuit de invalshoek van de wetgevingsjurist in op de vraag of integratie van de versnipperde regelgeving iets kan bijdragen aan een betere handhaving.
Voordeelstoerekening: leuker kunnen wij het niet maken, wel inzichtelijker
Authors: Engelen S.S.Y. , Keirse A.L.M. 
Published: July 2017

Voordeelstoerekening: leuker kunnen wij het niet maken, wel inzichtelijker
De Hoge Raad heeft op 8 juli 2016 in zijn arrest TenneT/ABB een nieuwe maatstaf geformuleerd voor voordeelstoerekening. Hierbij komt hij expliciet terug op zijn eerdere rechtspraak over dit leerstuk, zoals neergelegd in artikel 6:100 BW. De nieuwe maatstaf geeft niet alleen meer houvast bij de beoordeling van een beroep op voordeelstoerekening, maar schakelt het leerstuk van voordeelstoerekening bovendien gelijk met de wijze waarop de omvang van de aansprakelijkheid op grond van artikel 6:95 tot met 6:98 BW dient te worden vastgesteld. In deze bijdrage bespreken de auteurs de inhoud en implicaties van de nieuwe maatstaf voor personenschadezaken.
HR 7 oktober 2016, NJ 2017/73, m.nt. J. Spier (Vennemans-Kropmans/Gemeente Nijmegen)
Authors: Rijnhout R. 
Published: July 2017

HR 7 oktober 2016, NJ 2017/73, m.nt. J. Spier (Vennemans-Kropmans/Gemeente Nijmegen)
In Vennemans-Kropmans/Gemeente Nijmegen oordeelt de Hoge Raad dat voorwerpen die niet behoren tot de weg in de zin van artikel 6:174 BW een weg niet gebrekkig kunnen maken. Hij bevestigt daarmee de lijn in lagere rechtspraak. In de literatuur werd echter door sommigen verdedigd dat ieder voorwerp een weg gebrekkig kan maken, mits de weg daardoor niet meer voldoet aan de eisten van redelijk onderhoud. Die opvatting volgt de Hoge Raad niet, maar de vraag is of – met de komst van een directe verkeersverzekering – dat criterium niet toch weer aan betekenis zal gaan winnen.
Aansprakelijkheid voor schade door gasboringen
Authors: Emaus J.M. , Gijselaar E.C. 
Published: July 2017

Aansprakelijkheid voor schade door gasboringen. Rb. Noord-Nederland 1 maart 2017, ECLI:NL:RBNNE:2017:715 (Eisers/NAM en Staat)
Op 1 maart 2017 besliste de Rechtbank Noord-Nederland dat de NAM aansprakelijk is voor door inwoners van het Groningenveld geleden en nog te lijden immateriële schade en vermogensschade in de zin van gemist ongestoord woongenot waarvoor uitgaven zijn gedaan die vanwege de aardbevingen doel hebben gemist. De Rechtbank Noord-Nederland besliste voorts dat de Staat onzorgvuldig en aldus onrechtmatig heeft gehandeld jegens de 127 eisers in deze gevoegde zaak. Een schadevergoedingsverplichting heeft dat laatste oordeel echter niet opgeleverd. In deze bijdrage staat dit vonnis centraal en wordt zowel de beslissing in de verhouding eisers/NAM als die in de verhouding eisers/Staat bezien in het licht van rechtspraak van de Hoge Raad en het EHRM.
Social Cognitive Theory Correlates of Physical Activity in Inactive Adults with Multiple Sclerosis
Authors: Uszynski Marcin Kacper , Casey Blathin , Hayes Sara , Gallagher Stephen , Purtill Helen , Motl Robert W. , Coote Susan 
Published: July 2017

Background:
There is a growing body of evidence that physical activity (PA) improves symptoms of multiple sclerosis (MS). Despite the benefits of PA, people with MS are relatively inactive compared with their healthy counterparts. This study investigated associations between social cognitive theory (SCT) constructs and energy expenditure (EE) as an objective measure of PA in a sample of inactive people with MS.

Methods:
Participants (n = 65) completed several questionnaires and were assessed using standardized outcome measures as part of a cross-sectional analysis of baseline data from a randomized controlled trial (Step it Up).

Results:
The bivariate correlation analysis indicated that of all SCT constructs, only exercise self-efficacy was significantly correlated with EE (r = 0.297, P = .022). Multiple linear regression analysis found that exercise self-efficacy independently explained 9% of the variance in EE (R2 = 0.088). A model including exercise self-efficacy, exercise goal setting, exercise planning, and exercise benefits explained 17% of the variance in EE (F4,54 = 2.741, P = .038, R2 = 0.169). In this model, only exercise self-efficacy was significantly associated with EE scores (Exercise Self-Efficacy Scale β = .320, P = .016).

Conclusions:
The constructs of SCT explained little of the variance of objectively measured PA in a sample of inactive people with MS who volunteered for an exercise trial. The only significant variable was exercise self-efficacy, which confirms the importance of enhancing it through PA interventions.
A Critical Discourse Analysis of Donald Trump’s Language Use in US Presidential Campaign, 2016
Authors: Mohammadi Mohammad , Javadi Javad 
Published: July 2017

The present study reports on the latest and newest hot topic in the world, the United States Presidential Election. So, this is the newest attempt to explore and discover interrelation of discourse structures and ideological structures of Donald Trump’s acceptance speech in the United States Presidential Election, 2016 as a good sample of his language use in presidential campaign. In so doing, the current study utilizes Critical Discourse Analysis (CDA) model to unmask the use of power and hidden strategies through language use. Also we analyze and uncover the experiential, relational and expressive values of the wordings, metaphors and grammatical structures of Trump’s language use. Furthermore, this study tries to show that there are linguistic traces that depict the strategy and ideology in the text as well. The findings of the present study can be provocative for English foreign language learners to promote their analytical skills. Therefore, findings of the present article can be applied to English Reading Comprehension and Reading Journalistic Texts classes.
Silence and Blindness in Richard Wright’s Native Son
Authors: Onunkwo Chibuzo , Okolie Mary J.N. , Andrew Chigbu Chigbu , Christian Uzoma Ginikachi 
Published: July 2017

Richard Wright’s Native Son has often been read as a socially-oriented text, seemingly neglecting its existence as a literary construct. Such readings gear towards identifying the text with such societal ills as racism and environmental impact on the individual, as if these are the only business of the text.In this paper, however, attention shifts from such external referents to the text itself, deconstructing the meaning of blindness already ascribed to the text as well as the meaning of silence as it is denotatively known. The uncovering of the textual meaning of each of these concepts will also serve either to compliment a character or to disparage same, and then the interweave of both concepts will result in reading the text as a tragedy. This study will be anchored on the provisions of Derrida’s deconstructive criticism.
HEALTH TECHNOLOGY DISINVESTMENT WORLDWIDE: OVERVIEW OF PROGRAMS AND POSSIBLE DETERMINANTS
Authors: Orso Massimiliano , de Waure Chiara , Abraha Iosief , Nicastro Carlo , Cozzolino Francesco , Eusebi Paolo , Montedori Alessandro 
Published: July 2017

Objectives:In the past decade, there has been a growing interest in health technology disinvestment. A disinvestment process should involve all relevant stakeholders to identify and deliver the most effective, safe, and cost-effective healthcare interventions. The aim of the present study was to describe the state of the art of health technology disinvestment around the world and to identify parameters that could be associated with the implementation of disinvestment programs.Methods:A systematic review of the literature was performed from database inception to November 2014, together with the collection of original data on socio-economic indicators from forty countries.Results:Overall, 1,456 records (1,199 from electronic databases and 257 from other sources) were initially retrieved. After analyzing 172 full text articles, 38 papers describing fifteen disinvestment programs/experiences in eight countries were included. The majority (12/15) of disinvestment programs began after 2006. As expected, these programs were more common in developed countries, 63 percent of which had a Beveridge model healthcare system. The univariate analysis showed that countries with disinvestment programs had a significantly higher level of Human Development Index, Gross Domestic Product per capita, public expenditure on health and social services, life expectancy at birth and a lower level of infant mortality rate, and of perceived corruption. The existence of HTA agencies in the country was a strong predictor (p= .034) for the development of disinvestment programs.Conclusions:The most significant variables in the univariate analysis were connected by a common factor, potentially related to the overall development stage of the country.
Area‐Preserving Parameterizations for Spherical Ellipses
Authors: Guillén Ibón , Ureña Carlos , King Alan , Fajardo Marcos , Georgiev Iliyan , López‐Moreno Jorge , Jarabo Adrian 
Published: July 2017

AbstractWe present new methods for uniformly sampling the solid angle subtended by a disk. To achieve this, we devise two novel area‐preserving mappings from the unit square [0,1]2 to a spherical ellipse (i.e. the projection of the disk onto the unit sphere). These mappings allow for low‐variance stratified sampling of direct illumination from disk‐shaped light sources. We discuss how to efficiently incorporate our methods into a production renderer and demonstrate the quality of our maps, showing significantly lower variance than previous work.
The Effect of Low Frequency Whole Body Vibration and Impacts on Human Tracking Performance
Authors: Hall L.C. 
Published: July 2017

The crew of a military vehicle driven at speed across country is subjected to a high level of low frequency random vibration with impacts of variable severity superimposed at random intervals. Crew members are frequently expected to perform tasks whilst on the move. An experiment was carried out at the Royal Military College of Science (RMCS) to compare the effect on human response of three levels of whole body random z-axis acceleration, and of the lowest of these levels with two levels of randomly occuring impacts superimposed. The tracking errors generated by twelve subjects attempting a z-axis zero order compensatory tracking task whilst exposed to these vibrations were measured. The results suggest that for the random vibration inputs the mean absolute error increases linearly with rms acceleration, but that the additional error due to the impacts increases in proportion to the peak acceleration raised to the power 2.5.
Safety and Efficacy of Nivolumab in Combination With Ipilimumab in Metastatic Renal Cell Carcinoma: The CheckMate 016 Study
Authors: Hammers Hans J. , Plimack Elizabeth R. , Infante Jeffrey R. , Rini Brian I. , McDermott David F. , Lewis Lionel D. , Voss Martin H. , Sharma Padmanee , Pal Sumanta K. , Razak Albiruni R. Abdul , Kollmannsberger Christian , Heng Daniel Y.C. , Spratlin Jennifer , McHenry M. Brent , Amin Asim 
Published: July 2017

Purpose Combination treatment with immune checkpoint inhibitors has shown enhanced antitumor activity compared with monotherapy in tumor types such as melanoma. The open-label, parallel-cohort, dose-escalation, phase I CheckMate 016 study evaluated the efficacy and safety of nivolumab plus ipilimumab in combination, and nivolumab plus a tyrosine kinase inhibitor in metastatic renal cell carcinoma (mRCC). Safety and efficacy results from the nivolumab plus ipilimumab arms of the study are presented. Patients and Methods Patients with mRCC received intravenous nivolumab 3 mg/kg plus ipilimumab 1 mg/kg (N3I1), nivolumab 1 mg/kg plus ipilimumab 3 mg/kg (N1I3), or nivolumab 3 mg/kg plus ipilimumab 3 mg/kg (N3I3) every 3 weeks for four doses followed by nivolumab monotherapy 3 mg/kg every 2 weeks until progression or toxicity. End points included safety (primary), objective response rate, and overall survival (OS). Results All patients in the N3I3 arm (n = 6) were censored at the time of analysis as a result of dose-limiting toxicity or other reasons. Forty-seven patients were treated in both the N3I1 and the N1I3 arm, and baseline patient characteristics were balanced between arms. Grade 3 to 4 treatment-related adverse events were reported in 38.3% and 61.7% of the patients in the N3I1 and N1I3 arms, respectively. At a median follow-up of 22.3 months, the confirmed objective response rate was 40.4% in both arms, with ongoing responses in 42.1% and 36.8% of patients in the N3I1 and N1I3 arms, respectively. The 2-year OS was 67.3% and 69.6% in the N3I1 and N1I3 arms, respectively. Conclusion Nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising OS in patients with mRCC.
La autoficción: simulacro de teoría o desfiguraciones de un género
Authors: Diaconu Diana 
Published: July 2017

El objetivo de esta contribución es ofrecer una visión crítica y un balance del estado actual de la reflexión sobre la autoficción en el ámbito hispanoamericano. Con este propósito ubico y analizo los principales lugares comunes en las actuales propuestas teóricas y críticas sobre la autoficción, tratando de analizar en qué sentidos distorsionan el panorama actual de una teoría de la autoficción todavía en proceso de construcción. Señalar los lugares comunes de la crítica pasa a menudo por el análisis de las lecturas erróneas, que desenfocan planteamientos fundamentales acerca de la naturaleza de la autoficción, así como por la operación de rescate de sentidos esenciales, caídos en el olvido o mistificados. Finalmente, indico algunos caminos a seguir para la crítica, direcciones inexploradas o abandonadas antes de tiempo y que considero valiosas para una teoría de la autoficción. Recuperar la perspectiva sociocultural, que permite emprender la búsqueda del significado del género, ofrecería, además, la ventaja de hacer posible un análisis de las particularidades del género autoficcional en América Latina —tarea urgente y crucial de la teoría y la crítica literarias contemporáneas.
PSYCHO-PEDAGOGICAL CONDITIONS TO INCREASE COGNITIVE ACTIVITY OF JUNIOR SCHOOLCHILDREN
Authors: Dmitrieva L. G. , Nasyrova A. A. , Kolesnikova N. A. , Bunakova M. S. 
Published: July 2017

The article is devoted to the role of increase of junior schoolchildren’s cognitive activity as an important condition for the development of cognitive abilities of learners. Psycho-pedagogical support should be focused on the development of cognitive functions of junior schoolchildren, and psychologists and parents should be involved in this process, as well as the teachers. Traditionally, psycho-pedagogical support at primary school focuses on the child's adaptation to the new educational environment. We consider that a child needs the same support in the process of mastering the curriculum. There is no true support without an emotional involvement and empathy, and as a result cognitive activity of a child might suffer greatly. It was proven by empirical results obtained in an ordinary school, where no innovative teaching methods are used. At the end of primary school pupils have a significantly reduced motivation, teachers express no serious interest in problems of junior high school students. Not entirely satisfactory educational environment also could not provide a positive influence on the development of cognitive sphere.