bluuebunny/crossref_metadata_2025_split huggingface dataset:
UI/UX Design for Student Discussion Applications Based Felder Silverman Learning Style with the Design Thinking Method
Authors: HNW Syahuda Nahatmasuni  , Anisa Herdiani  , Ati Suci Dian Martha  
Published: September 2024

Telkom University is one of the educational institutions that implement asynchronous learning through its Learning Management System (LMS). Based on preliminary research conducted with 37 respondents, just 13.5% of the participants LMS using a smartphone, because responsiveness issue. The Discussion Forum is a frequently used feature with high student interaction. However, this feature has several shortcomings, such as the lack of responsiveness in the mobile web interface and the limited interaction between users and professors. This research will employ the Design Thinking methodology and adopt the Felder Silverman Learning Style (FSLS). The evaluation of the prototype design resulted in a System Usability Scale (SUS) testing score of 72.22 for the LMS Celoe website and 85.65 for the proposed UI/UX application. The SUS testing score for the LMS Celoe website falls within Quadrant C, indicating an acceptable level of acceptance with a grade C scale and a rating of "Good." On the other hand, the SUS testing score for the proposed UI/UX application falls within Quadrant B, with an acceptable level of acceptance, a grade B scale, and an "Excellent" rating.
GaN lattice damage and GaN-HEMT metrology by cameraless T-ray imaging
Authors: Rahman Anis 
Published: September 2024

Abstract

Gallium nitride (GaN) film grown on a silicon substrate has been investigated for high electric field induced lattice damage via cameraless terahertz (T-ray) imaging technique. In addition, T-ray time-domain spectroscopy (TGS) has been conducted on the same GaN film as a function of depth via nondestructive and noncontact pump-probe technique. This is termed as the deep-level TDS. Further, a pair of GaN high electron mobility transistor (HEMT) dies have been imaged at the channel area where the deep-level TDS has also been conducted. A pristine die has been compared with a similar die that was irradiated with mild nuclear radiation. The channel width measured via T-ray metrology of both dies matches those determined from the optical microscope images. However, T-ray deep-level spectral analysis of both dies reveal that the pristine die’s channel structure remains unaffected up to 5.5 THz up to a depth of 3 µm while that of the irradiated die’s channel structure’s performance is shrunk to 4.2 THz to the same depth of 3 µm. details of data and analysis have been discussed. The technique may be deployed to other similar systems and devises.
Performance Evaluation of the High Rise Steel Building With Outrigger and Belt System
Authors: Pujari Atul B. , Gunjal Swapnil P. 
Published: September 2024

Abstract

Pushover static analysis is a crucial technique in structural engineering used to analysis of structure under earthquake loads. Pushover analysis provides essential inputs into the behavior of structures beyond their elastic limits, offering engineers a thorough understanding of how structures respond to worst conditions. This research will explore the details of pushover static analysis, its importance, and the process involved in performing this analysis. In seismic analysis, assessing how buildings and compositions behave under different forces is of paramount importance. Conventional analysis methods are limited in their ability to capture complex interactions beyond the elastic limit, as they typically focus on linear behavior. As a result, these methods may not accurately predict the response of a structure when it exceeds its elastic limit. Pushover static analysis, also referred as nonlinear static analysis, addresses this limitation by accurately modeling the inelastic performance of structures. The process entails monitoring the progression of yielding, the formation of plastic hinges, and the eventual failure of different structural elements. This data is then utilized to plot a capacity curve, depicting the total force in relation to the displacements. During this analysis, displacement is progressively increasing from zero to a defined ultimate displacement or until the building can no longer sustain additional loads. This method is extensively used to estimate the axial and flexural capacity of existing structures and to determine the seismic requirement of modelled building during selected earthquake scenarios. It is also useful for evaluating the sustainability of new structural designs during linear behavior. The practicality and computational simplicity of pushover analysis have proven to its applications in several earthquake design guidelines (such as FEMA 356 and ATC 40) and design codes (including PCM 3274 & Eurocode 8) over the past few years. The research involved a comprehensive comparison of two pushover methods, namely displacement control and full load method, for steel frame structures with identical G + 17 configuration. The study focused on analyzing the maximum story drifts, story displacements, and hinge responses to seismic loads. Steel frameworks have been found to exhibit better seismic performance than Reinforced Cement Concrete (RCC) structures, especially in areas prone to earthquakes. This makes them a more favorable choice for construction in such regions. The analysis also reveals that, although DCM provides detailed insights, it requires a lot of resources, which makes FLM a more practical choice for routine market applications.
Impact of a New Case-Based Payment Scheme on Volume Distribution Across Public Hospitals in China: Does 'Same Disease, Same Price' Matter
Authors: Yu Meiteng , Liu Jing , Zhang Tao 
Published: September 2024

Abstract

Background
In China, the disparity in patient distribution across hospitals of varying levels is largely caused by fee-for-service (FFS) payment. To reduce this inequality, an innovative payment called “payment method by disease types with point counting” was launched in Zhejiang province, and was later integrated with “same disease, same price” policy. This study aimed to investigate the impact of this payment on service volume distribution across Chinese public hospitals.
Methods
Data was obtained from 104 hospitals, with 12 tertiary and 14 secondary hospitals extracted from each of the four regions: intervention groups in Jinhua and Hangzhou, and control groups in Taizhou and Ningbo. Using a total of 3848 observation points, two sets of controlled interrupted time series analyses were performed to evaluate the impact of this new case-based payment with and without “same disease, same price” on the proportion of discharges, total medical revenue and hospitalization revenue, as well as Herfindahl-Hirschman Index (HHI).
Results
After the introduction of the new case-based payment without “same disease, same price”, the proportion of discharges (β6=-0.1074, p = 0.047), total medical revenue (β6=-0.0729, p = 0.026) and hospitalization revenue (β6=-0.1062, p = 0.037) of secondary hospitals significantly decreased. Despite no statistical significance, the proportion in tertiary hospitals increased. By incorporating “same disease, same price”, the proportion of discharges (β6 = 0.2015, p = 0.031), total medical revenue (β6 = 0.1101, p = 0.041) and hospitalization revenue (β6 = 0.1248, p = 0.032) of secondary hospitals increased, yet differences in tertiary hospitals were insignificant. The HHI (β7 = 0.0011, p = 0.043) presented an upward trend during the pilot period of this payment without “same disease, same price”, while after the implementation of this payment combined with “same disease, same price”, the HHI (β6=-0.0234, p = 0.021) decreased immediately.
Conclusion
This new case-based payment scheme does not promote rational volume distribution among different-level hospitals, yet “same disease, same price” may help. Policymakers should balance interests of hospitals when devising payment mechanisms, and regulate providers’ potential strategic behavior.
Microdiscectomy Combined with Autologous Microfragmented Adipose Tissue Injection for the Treatment of Low Back Pain due to Intervertebral Lumbar Disc Degeneration
Authors: Conti Michele , Giovannini Matteo , Bianchini Alessandra , Lozza Alessandro , Cainelli Filippo , Mattioli Lorenzo 
Published: September 2024

Abstract

Background
Low back pain (LBP) due to intervertebral disc (IVD) degeneration presents a major clinical challenge, impacting quality of life and imposing substantial economic burdens. Conventional treatments often provide symptomatic relief without addressing underlying disc degeneration. This study evaluates the efficacy of microdiscectomy combined with autologous microfragmented adipose tissue (MAT) injection in treating LBP associated with lumbar disc degeneration.
Methods
In this prospective case series, 32 adults with chronic LBP (> 6 months) with episode of sciatic nerve pain and MRI-confirmed Pfirrmann grade ≥ 3 IVD degeneration underwent microdiscectomy followed by autologous MAT injection using Lipocell technology. MAT was injected intradiscally, intra-facetally, or into the multifidus muscle based on individual MRI findings. Outcomes were assessed using the Visual Analog Scale (VAS), Oswestry Disability Index (ODI), Goutallier classification for muscle degeneration, and Pfirrmann classification for disc degeneration at baseline, 3 months, and 12 months post-treatment.
Results
Significant reductions in VAS (mean: 7.4 to 1.5 at 3 months, 0.3 at 12 months; p < 0.01) and ODI scores (mean: 52.9 to 24.9 at 3 months, 9.5 at 12 months; p < 0.01) were observed. Improvements were also noted in Goutallier classification, indicating reduced fatty infiltration in multifidus muscle, and in Pfirrmann grades, suggesting enhanced disc structure and reduced degeneration.
Conclusions
Combining microdiscectomy with autologous MAT injection offers effective pain relief and functional improvement in patients with LBP due to IVD degeneration, addressing both symptoms and underlying pathology. These findings support further investigation into this combined therapeutic approach.
Map-based cloning of Zmccr3 and its network construction and validation for regulating maize seed germination
Authors: Tao yongsheng , Feng Liqing , Zhou Mingting , Tao Anyan , Ma Xiaolin , Zhang He , Duan Huijun 
Published: September 2024

Abstract

Abstract:
Seed dormancy (SD) and pre-harvest sprouting (PHS) impact the yield and quality of grain and hybrid seed production. Although the benefits of studying SD and seed germination (SG) during seed development have been established, research on the genetic variation and molecular regulation of SD, as well as the transition from SD to SG, remains limited. In this study, 40X BSA-QTL resequencing and linkage analysis were employed for QTL mapping of the maize vp16 mutant of PHS. Through genetic and molecular biological methods, the candidate gene was identified as Zmccr3. This gene encodes cinnamoyl-CoA reductase 3 (ccr3), which participates in the phenylalanine pathway to regulate lignin metabolism, thereby affecting SG. Based on RNA-seq of 36 samples at two stages of grain development with extreme PHS traits from three maize populations, a Weighted gene coexpression network analysis (WGCNA) related to SD and SG formation was constructed. Ten target genes and three pathways (lipid metabolism, reactive oxygen species) homeostasis under redox of electrophilic compounds, and cell wall oligosaccharide metabolism) were identified. Using WGCNA, vp16-RNA-seq, vp16-iTRAQ, and physiological and biochemical evidence, the Zmccr3 pathway was established and validated. This pathway involves Zmccr3-mediated energy supply for lipid metabolism, redox of electrophilic compounds, gibberellic acid levels or signaling regulation for endosperm weakening, and cell wall metabolism, affecting SG or SD. These findings have significant theoretical and practical implications for understanding the genetic basis of maize PHS and SD, increasing genetic resources, and improving trait genetics.
Discectomy combined with the Coflex interspinous stabilization device versus simple discectomy for lumbar disc herniation: Long-term follow-up
Authors: Qian Yunfan , Li Yimin , Zhong Xiqiang , Shen Guangjie , Tang Chengxuan , He Shaoqi 
Published: September 2024

Abstract

Objective:To evaluate the long-term efficacy of the Coflex dynamic stabilization device in the treatment of lumbar disc herniation (LDH) versus simple discectomy.
Methods: We retrospectively analyzed 85 patients who underwent surgery for LDH between January 2009 and December 2013. Eligible patients with single-segment LDH were divided into two groups: discectomy with Coflex (Coflex group) and simple discectomy (SD group). The patient characteristics, surgical outcomes, operation time, blood loss, clinical and radiological features, complications, and reoperation rates were compared between both groups. In the Coflex group, the intervertebral height, intervertebral foramen height, and range of motion (ROM) of the treated segment were calculated from radiographs. Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) scores were assessed for both groups before surgery, at 1 month, one year after surgery, and at final follow-up.
Results: The mean age, sex, body mass index (BMI), symptom duration, follow-up period, operated level, and Pfirrmann grade before surgery did not differ significantly between groups. The results showed significant improvements in the VAS and ODI scores in each group (P<0.05) after surgery. However, there were no significant differences in the VAS and ODI scores between both groups at 1 month or 1 year postoperatively. However, at the final follow-up, the VAS and ODI scores in the Coflex group were lower than those in the SD group(P<0.05). In the Coflex group, the anteriordisc height, posterior disc height, and intervertebral foramen height improved postoperatively. However, at the last follow-up, these values showed varying degrees of decline, returning to preoperative levels. In the flexion–extension radiographs, the ROM showed a significant decrease postoperatively, while the ROM continued to increase at the last follow-up (P<0.05). The mean operation time and blood loss were higher in the Coflex group than in the SD group(P<0.05). During the follow-up period, 3 patients (7.5%) in the Coflex group experienced complications, and 3 (7.5%) underwent secondary surgery. In the SD group, 1 patient (2.22%) experienced complications, and 5 (11.1%) underwent secondary surgery.
Conclusions This study revealed that the Coflex maintains the disc height of the surgical segment for a short period and preserves a limited ROM. Both Coflex and simple discectomies proved effective in treating LDH. However, long-term follow-up indicated that discectomy combined with Coflex produced superior clinical outcomes compared to simple discectomy, with fewer complications. Consequently, Coflex is a safe and effective treatment option for LDH.
On the mechanism of the Hainan Island modulating extreme rainfall along the South China coast via thermodynamic forcing
Authors: Gao Xiaoyu , Yin Jinfang , Yun Yuxing , Zhang Shuqin 
Published: September 2024

Abstract

Warm moist airflow from the northern South China Sea produces a large amount of warm-season rainfall along the South China coast (SCC). Currently, the prediction skill for coastal extreme rainfall (ER) remains very poor, which can be partly attributed to the lack of observations over sea. This study provides a new perspective that the Hainan Island modulates the warm moist airflow in the planetary boundary layer (PBL) and thus fulfills an important role in the production of coastal ER. Based on observations in 30 warm seasons during 1988–2017, this study defines 215 days as the coastal ER days using the 99th percentile threshold of hourly rainfall. On the ER days, the diabatic heating renders the PBL over Hainan Island much warmer than that over the sea area near SCC, and the strong southwest wind over sea induces warm advection from the island. The heat budget analysis indicates the Hainan Island as the main heat source for the sea area near SCC. Moreover, the strong zonal temperature gradient east of the island enhances the low-level atmospheric baroclinicity, which is the key reason for the strengthening of the south wind component within the PBL and the frequent occurrence of boundary layer jets (BLJs). A typical heavy rainfall event is studied using the Weather Research and Forecasting (WRF) model to further discuss the impact of Hainan Island on the coastal ER. In the control experiment, the WRF model reasonably reproduces the distribution and evolution of coastal ER. Two additional sensitivity experiments are conducted to reduce the temperature in the PBL over Hainan Island using data assimilation. The presence of a colder island yields a weaker zonal temperature gradient to the east, which reduces the south wind component in the PBL and thus the moisture convergence along SCC. The weaker warm advection from Hainan Island also results in a colder PBL over sea and a weaker land-sea thermal contrast. Notably, ER along the SCC is decreased by 58% and 88% with the PBL over Hainan Island cooled by ~ 0.3 and ~ 0.5 K, respectively. These results suggest a probable improvement in the prediction skill for SCC rainfall via the increased application of enhanced observations near Hainan Island.
An Open Source Algorithm for Autoregulation-Based Neuromonitoring is Associated with Long-Term Outcome in Pediatric Traumatic Brain Injury
Authors: Twist Eris van , Robles Tahisa B. , Formsma Bart , Ketharanathan Naomi , Hunfeld Maayke , Buysse C. M. , de Hoog Matthijs , Schouten Alfred C. , de Jonge Rogier C.J. , Kuiper Jan W. 
Published: September 2024

Abstract

Purpose: This study aimed to develop an open-source algorithm for the pressure-reactivity index (PRx) to monitor cerebral autoregulation (CA) in pediatric severe traumatic brain injury (sTBI) and compared derived optimal cerebral perfusion pressure (CPPopt) with real-time CPP in relation to long-term outcome.
Methods: Retrospective study in children (< 18 years) with sTBI admitted to the pediatric intensive care unit (PICU) for intracranial pressure (ICP) monitoring between 2016 and 2023. ICP was analyzed on an insult basis and correlated with outcome. PRx was calculated as Pearson correlation coefficient between ICP and mean arterial pressure. CPPopt was derived as weighted average of CPP-PRx over time. Outcome was determined via Pediatric Cerebral Performance Category (PCPC) scale at one year post-injury. Logistic regression and mixed effect models were developed to associate PRx and CPPopt with outcome.
Results: 50 children were included, 35 with favorable (PCPC 1 – 3) and 15 with unfavorable outcome (PCPC 4 – 6). ICP insults correlated with unfavorable outcome at 20 mmHg for 7 min duration. Mean CPPopt yield was 75.4% of monitoring time. Mean and median PRx and CPPopt yield associated with unfavorable outcome, with odds ratio (OR) 2.49 (1.38 – 4.50), 1.38 (1.08 – 1.76) and 0.95 (0.92 – 0.97) (p < 0.001). PRx thresholds 0.0, 0.20, 0.25 and 0.30 resulted in OR 1.01 (1.00 – 1.02) (p < 0.006). CPP in optimal range associated with unfavorable outcome on day four (-0.027, p = 0.020).
Conclusion:Our algorithm can obtain optimal targets for pediatric neuromonitoring that showed association with long-term outcome, and is now available via Github.
Clinical significance of sarcopenia in children with neuroblastic tumors
Authors: Kudo Wataru , Terui Keita , Furugane Ryoya , Takenouchi Ayako , Komatsu Shugo , Kawaguchi Yunosuke , Nishimura Katsuhiro , Katsumi Daisuke , Hishiki Tomoro 
Published: September 2024

Abstract

Purpose To elucidate the clinical significance of sarcopenia in children with neuroblastic tumors (NTs).Methods We conducted a retrospective observational study and analyzed the z-scores for height, body weight, body mass index, and skeletal muscle index (HT-z, BW-z, BMI-z, and SMI-z) along with the clinical characteristics of 36 children with NTs. SMI-z was calculated from 138 computed tomography scans at diagnosis, during treatment, and at follow-up. The International Neuroblastoma Risk Group classification was used to identify high-risk groups. We analyzed the data at diagnosis for prognostic analysis and changes over time after diagnosis in the HT-z, BW-z, BMI-z, and SMI-z groups.Results Among the four parameters at diagnosis, only SMI-z predicted overall survival (hazard ratio, 0.58; 95% confidence interval, 0.34–0.99). SMI-z, HT-z, and BW-z significantly decreased over time after diagnosis (P < 0.05), while BMI-z did not (P = 0.11). In surviving high-risk NT cases without disease, SMI-z, HT-z, and BW-z significantly decreased over time (P < 0.05), while BMI-z did not (P = 0.43).Conclusion In children with NT, the SMI-z at diagnosis was a significant prognostic factor and decreased during treatment and follow-up along with HT-z and BW-z. Monitoring muscle mass is important because sarcopenia may be associated with growth impairment.
Flow characteristics of sintered Titanium-based porous transport layers using machine learning
Authors: Froning Dieter , Hoppe Eugen , Müller Martin , Peters Ralf 
Published: September 2024

Abstract

Porous transport layers, sintered from sphere-based titanium material, can beused in electrolyzers. A sedimentation-based stochastic sphere model was usedto create many versions of a sphere-based micro-structure. Aided by Lattice-Boltzmann simulations, the permeability was calculated based on the artificialmicro-structures. These data were then used to train a convolutional neural net-work in order to characterize material on the basis of its micro-structure. Binaryimage series from the real material of porous transport layers were characterizedusing a deep learning model trained with artificial data. A reasonable degree ofaccuracy was achieved by the neural network in the prediction of the through-plane permeability of the real material, when the samples were manufacturedfrom spherical particles.
The Essence of Nourishment: Tracing the Levels of Essential Mineral Elements in the Colostrum Milk of Full-Term Mothers
Authors: Jonathan Justice Wiston Amstrong , Kabotso Danie Elorm Kwame , Essumang David Kofi , Bentum John Kwesi , Anak Jesse Azebiik , Gborgblorvor Innocentia Ruby , Danyo Emmanuel Kormla , Mbroh Hintermann , Tampuori John , Asmah Richard Harry 
Published: September 2024

Abstract

Introduction: Mineral elements in colostrum play important roles in the growth and development of neonates.Objective The study characterized the levels of ten mineral elements in the colostrum (CM) of full-term mothers in a previously unstudied population and compared them with those determined elsewhere.Methodology: Forty-seven (47) respondents took part in the study. Each mother donated twelve millilitres (12 mL) colostrum sample from the day of delivery to four days postpartum following standardized procedures. 10 ml of each sample was digested using EPA Method 3010A and 200.7 and examined using inductively coupled plasma optical emission spectrometer. IBM Statistics SPSS Version 26.0, Excel Toll Pak and XLSTAT 2022.4.1.1377 were used to analyse the data.Results Concentrations mineral elements quantified ranged from 0.1 ± 0.0 mg/L (Se; lowest) to 602.6 ± 77.6 mg/L (K; highest). Positive significant correlations were observed between Ca and K (r = 0.604; p < 0.0001), Cu and S (r = 0.576; p < 0.0001), S and Na (r = 0.483; p = 0.001), Na and Fe (r = 0.469; p = 0.001), Zn and Ca (r = 0.462; p = 0.001).Conclusion Three factors contributed to the variation of mineral elements in the colostrum accounting for a total of 65.73% in the dataset. Significant relationships were found between K levels in CM and employment status of mothers (p = 0.047) and levels of Zn in CM and maternal parity (p = 0.028). Concentrations of the mineral elements detected compared favourably well with those reported in the literature worldwide.