bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iodine knowledge is positively associated with dietary iodine intake among women of childbearing age in the UK and Ireland
Authors: O’Kane S. Maria , Pourshahidi L. Kirsty , Farren Kayla M. , Mulhern Maria S. , Strain J. J. , Yeates Alison J. 
Published: November 2016

AbstractAdequate I intake is important before conception and during pregnancy for optimal infant neurodevelopment. Recent studies have highlighted the prevalence of I deficiency in the UK and Ireland. It is possible that optimal I intake may be impeded by a poor knowledge of I nutrition. This study aimed to investigate I knowledge among women of childbearing age in the UK and Ireland and to determine whether a relationship exists between I knowledge and dietary I intake. Females (aged 18–45 years) were invited to complete an online questionnaire, which assessed knowledge of I and estimated dietary I intake using a FFQ. A total of 520 females of childbearing age completed the study. I knowledge was poor; only one-third (32 %) of the participants correctly identified pregnancy as the most important stage of the lifecycle for I, and 41 % of participants could not correctly identify any health problem related to I deficiency. The median daily I intake was estimated as 152 µg/d. Almost half (46 %) of the participants failed to meet dietary recommendations (140 µg/d) for I. A higher dietary I intake was positively associated with greater I knowledge (r 0·107; P=0·016). This study suggests that knowledge of I nutrition is low among women of childbearing age, and those with a greater knowledge of I nutrition had a higher dietary I intake. Initiatives to educate women of childbearing age on the importance of I nutrition should be considered as part of a larger public health strategy to address I deficiency.
THE REPUBLIC OF THE REFUGEES: EARLY MODERN MIGRATIONS AND THE DUTCH EXPERIENCE
Authors: JANSSEN GEERT H. 
Published: November 2016

ABSTRACTThis essay surveys the wave of new literature on early modern migration and assesses its impact on the Dutch golden age. From the late sixteenth century, the Netherlands developed into an international hub of religious refugees, displaced minorities, and labour migrants. While migration to the Dutch Republic has often been studied in socio-economic terms, recent historiography has turned the focus of attention to its many cultural resonances. More specifically, it has been noted that the arrival of thousands of newcomers generated the construction of new patriotic narratives and cultural codes in Dutch society. The experience of civil war and forced migration during the Dutch revolt had already fostered the development of a national discourse that framed religious exile as a heroic experience. In the seventeenth century, the accommodation of persecuted minorities could therefore be presented as something typically ‘Dutch’. It followed that diaspora identities and signs of transnational religious solidarity developed into markers of social respectability and tools of cultural integration. The notion of a ‘republic of the refugees’ had profound international implications, too, because it shaped and justified Dutch interventions abroad.
Helminth parasites of South American fishes: current status and characterization as a model for studies of biodiversity
Authors: Luque J.L. , Pereira F.B. , Alves P.V. , Oliva M.E. , Timi J.T. 
Published: November 2016

AbstractThe South American subcontinent supports one of the world's most diverse and commercially very important ichthyofauna. In this context, the study of South American fish parasites is of increased relevance in understanding their key roles in ecosystems, regulating the abundance or density of host populations, stabilizing food webs and structuring host communities. It is hard to estimate the number of fish parasites in South America. The number of fish species studied for parasites is still low (less than 10%), although the total number of host–parasite associations (HPAs) found in the present study was 3971. Monogeneans, with 835 species (1123 HPAs, 28.5%), and trematodes, with 662 species (1127 HPAs, 30.9%), are the more diverse groups. Data gathered from the literature are useful to roughly estimate species richness of helminths from South American fish, even though there are some associated problems: the reliability of information depends on accurate species identification; the lack of knowledge about life cycles; the increasing number of discoveries of cryptic species and the geographically biased number of studies. Therefore, the closest true estimations of species diversity and distribution will rely on further studies combining both molecular and morphological approaches with ecological data such as host specificity, geographical distribution and life-cycle data. Research on biodiversity of fish parasites in South America is influenced by problems such as funding, taxonomic impediments and dispersion of research groups. Increasing collaboration, interchange and research networks in the context of globalization will enable a promising future for fish parasitology in South America.
Cross-reactivity of the 31 kDa antigen of Angiostrongylus cantonensis – Dealing with the immunodiagnosis of meningoencephalitis
Authors: MORASSUTTI ALESSANDRA L. , RASCOE LISA N. , HANDALI SUKWAN , DA SILVA ALEXANDRE J. , WILKINS PATRICIA P. , GRAEFF-TEIXEIRA CARLOS 
Published: November 2016

SUMMARYThe primary causative agent of eosinophilic meningoencephalitis (EoM) in endemic regions is the nematode Angiostrongylus cantonensis. The occurrence of EoM was previously restricted to countries in Southeast Asia and the Pacific Islands; however, more recently, it has been reported from other regions, including Brazil. The commonly used diagnosis is detection of specific antibody reactivity to the 31 kDa antigen, which is derived from female worm somatic extracts. Here we report the occurrence of cross-reactivity to this antigen in sera from other parasitic infections, especially those that may cause EoM, such as gnathostomiasis, toxocariasis, hydatidosis and strongyloidiasis. We also demonstrated that the cross-reactivity, in part, is dependent of the concentration of antigen used in Western blot assays. We discuss the importance of these findings on the interpretation of this test.
Life satisfaction of migrants, stayers and returnees: reaping the fruits of migration in old age?
Authors: BAYKARA-KRUMME HELEN , PLATT LUCINDA 
Published: November 2016

ABSTRACTThis paper evaluates the effects of migration on life satisfaction in later life. We compare the life satisfaction of older migrants with that of non-migrants and return migrants of a similar age and originating from the same regions in Turkey. Turks constitute one of the largest migrant groups in Europe, and the growing population of older Turkish migrants display greater risks of loneliness and material disadvantage compared to native-born populations in Europe. However, compared to their non-migrant peers from the country of origin, older migrants may experience gains from migration that are reflected in their life satisfaction. Using the 2000 Families Study, a large survey of Turkish migrants from the peak labour migration period and their non-migrant comparators, we investigate whether life satisfaction of migrants and stayers differs and the possible causes of any differences. We find that both migrants and return migrants experience higher life satisfaction in old age than stayers. However, the gap cannot be explained by the classical determinants of life satisfaction such as income, health, partner and friends, or religiosity, nor by the better outcomes of the migrants’ children. We discuss possible reasons for this migration satisfaction advantage.
Dynamic intertextuality in the Miracula Nynie episcopi: remembering Arator's Historia apostolica
Authors: Hillier Richard 
Published: November 2016

AbstractIt has long been acknowledged that Arator, author of the sixth-century Historia apostolica, was one of the Christian Latin writers with whom the author of the eighth-century Miracula Nynie episcopi was familiar. However, until now the critical consensus has been that the later poem was little more than a ‘cut-and-paste’ pastiche: Arator's phrases had been chosen largely for their metrical suitability; some were perhaps just ‘recycled’ borrowings rather than evidence of first-hand reading. But a close comparison of the two texts shows that the extent of the unknown author's borrowings from Arator is far greater than has hitherto been realized. Furthermore it reveals a detailed knowledge of the earlier poem, indeed an intimate understanding of it. This is evident not only in his poetic diction but also in his imitation of specific narrative detail where he displays a tendency to simplify his model, rendering the abstract concrete and the figurative literal.
Exploring genotype concordance in epidemiologically linked cases of tuberculosis in New York City
Authors: ROBBINS R. S. , PERRI B. R. , AHUJA S. D. , ANGER H. A. , SULLIVAN MEISSNER J. , SHASHKINA E. , KREISWIRTH B. N. , PROOPS D. C. 
Published: November 2016

SUMMARYComparing genotype results of tuberculosis (TB) isolates from individuals diagnosed with TB can support or refute transmission; however, these conclusions are based upon the criteria used to define a genotype match. We used a genotype-match definition which allowed for variation in IS6110restriction fragment length polymorphism (RFLP) to support transmission between epidemiologically linked persons. Contacts of individuals with infectious TB (index cases) diagnosed in New York City from 1997 to 2003 who subsequently developed TB (contact cases) from 1997 to 2007 were identified. For each contact case and index case (case-pair), isolate genotypes (spoligotype and RFLP results) were evaluated. Isolates from case-pairs were classified as exact or non-exact genotype match. Genotypes from non-exact match case-pairs were reviewed at the genotyping laboratory to determine if the isolates met the near-genotype-match criteria (exactly matching spoligotype and similar RFLP banding patterns). Of 118 case-pairs identified, isolates from 83 (70%) had exactly matching genotypes and 14 (12%) had nearly matching genotypes (supporting transmission), while the remaining 21 (18%) case-pairs had discordant genotypes (refuting transmission). Using identical genotype-match criteria for isolates from case-pairs epidemiologically linked through contact investigation may lead to underestimation of transmission. TB programmes should consider the value of expanding genotype-match criteria to more accurately assess transmission between such cases.
Predictive modelling of Ross River virus notifications in southeastern Australia
Authors: CUTCHER Z. , WILLIAMSON E. , LYNCH S. E. , ROWE S. , CLOTHIER H. J. , FIRESTONE S. M. 
Published: November 2016

SUMMARYRoss River virus (RRV) is a mosquito-borne virus endemic to Australia. The disease, marked by arthritis, myalgia and rash, has a complex epidemiology involving several mosquito species and wildlife reservoirs. Outbreak years coincide with climatic conditions conducive to mosquito population growth. We developed regression models for human RRV notifications in the Mildura Local Government Area, Victoria, Australia with the objective of increasing understanding of the relationships in this complex system, providing trigger points for intervention and developing a forecast model. Surveillance, climatic, environmental and entomological data for the period July 2000–June 2011 were used for model training then forecasts were validated for July 2011–June 2015. Rainfall and vapour pressure were the key factors for forecasting RRV notifications. Validation of models showed they predicted RRV counts with an accuracy of 81%. Two major RRV mosquito vectors (Culex annulirostris and Aedes camptorhynchus) were important in the final estimation model at proximal lags. The findings of this analysis advance understanding of the drivers of RRV in temperate climatic zones and the models will inform public health agencies of periods of increased risk.
Tuberculosis infection testing in HIV-positive men who have sex with men from Xi'an China
Authors: XIN H. N. , LI X. W. , ZHANG L. , LI Z. , ZHANG H. R. , YANG Y. , LI M. F. , FENG B. X. , LI H. J. , GAO L. 
Published: November 2016

SUMMARYIn individuals with latent tuberculosis (TB) infection, those living with human immunodeficiency virus (HIV) had a 20–37 times higher risk of developing active TB compared to those without HIV infection. Systematic testing and treatment of latent TB infection are priorities in HIV-infected persons. In China, the prevalence of HIV infection in men who have sex with men (MSM) has gradually increased in the past decade. However, the prevalence of TB infection has been studied sparsely in HIV-infected MSM. Hence, we conducted a pilot study in MSM living with HIV infection in Xi'an city to evaluate TB infection status by means of interferon-γrelease assay (IGRA). A total of 182 HIV-infected MSM were included in this study, the prevalence of IGRA positivity was observed to be 8·79% (16/182). IGRA quantitative results were not statistically influenced by the CD4 cell counts of the study participants. However, IGRA positivity was found to be lower than our previously reported data from the general population. This suggests that immunological deficiency might decrease the sensitivity of IGRA and thus increase the number of false negatives. Our primary results, suggesting systematic testing and treatment of latent TB infection together with active case-finding, were equally important for TB control in persons living with HIV infection.
Dietary DHA and health: cognitive function ageing
Authors: Cardoso Carlos , Afonso Cláudia , Bandarra Narcisa M. 
Published: November 2016

AbstractDHA is a key nutritionaln-3 PUFA and needs to be supplied by the human diet. DHA is found in significant amounts in the retinal and neuronal cell membranes due to its high fluidity. Indeed, DHA is selectively concentrated in the synaptic and retinal membranes. DHA is deemed to display anti-inflammatory properties and to reduce the risk of CVD. Consumption of larger amounts of DHA appears to reduce the risk of depression, bipolar disorder, schizophrenia and mood disorders. Conversely, it has been shown that loss of DHA from the nerve cell membrane leads to dysfunction of the central nervous system in the form of anxiety, irritability, susceptibility to stress, dyslexia, impaired memory and cognitive functions, and extended reaction times. DHA plays an important role in ensuring a healthy ageing, by thwarting macular degeneration, Alzheimer’s disease, and other brain disorders at the same time as enhancing memory and strengthening neuroprotection in general. A reduced level of DHA is associated with cognitive decline during ageing. Different mechanisms for this fundamental DHA role have been put forward. Namely, neuroprotectin D1, a DHA derivative, may support brain cell survival and repair through neurotrophic, anti-apoptotic, and anti-inflammatory signalling. Many of the effects of DHA on the neurological system may be related to signalling connections, thus leading to the study of the related signalolipidomics. Therefore, the present review will focus on the influence of DHA deficiency upon ageing, with specific emphasis upon neurological disorders related to cognitive function and mental health.
LEGAL POWERS IN PRIVATE LAW
Authors: Essert Christopher 
Published: November 2016

ABSTRACTThis article explores the nature and role of legal powers in private law. I show how powers are special in that they allow agents to change their (and others’) legal circumstances merely by communicating an intention to do so, without having also to change the nonnormative facts of the world. This feature of powers is, I argue, particularly salient in private law, with its correlative or bipolar normative structure; understanding powers and their role in private law thus requires careful attention to this correlativity. In the final section, I argue that the correct explanation of a variety of substantive problems in private law, many having to do with the role of a party's intention, turns on correctly understanding legal powers.
Latino mothers’ beliefs about child weight and family health
Authors: Martinez Suzanna M , Rhee Kyung E , Blanco Estela , Boutelle Kerri 
Published: November 2016

AbstractObjectiveThere is a need to address cultural beliefs and parenting practices regarding childhood obesity to design effective weight-control programmes for overweight/obese US Latino children. The purpose of the current study was to explore cultural beliefs about children’s weight, understand parent perceptions on feeding their children, and explore barriers that interfere with a healthy lifestyle.DesignFour focus groups were conducted in Spanish with forty-one Latino mothers of elementary school-age children from San Diego County, California between April and May 2011. Cultural viewpoints about overweight status among children and barriers to leading a healthy lifestyle were explored. Focus group discussions were analysed based ona prioriand emergent themes.ResultsThree themes were identified: (i) mothers’ cultural beliefs about health that are barriers to family health; (ii) mothers as primary caretakers of their family’s health; and (iii) attitudes about targeting children’s weight. Mothers acknowledged the idea that ‘chubby is better’ is a misperception, yet having a ‘chubby’ child was preferred and even accepted. Mothers described fatalistic beliefs that contradicted existing knowledge of chronic disease and daily demands of Western culture as barriers to practising healthy behaviours in the home as the family caretaker.ConclusionsThese findings may be used to inform more culturally appropriate research to address US Latino health. Increasing awareness of cultural beliefs and daily circumstance could help to address obesity more directly and thereby overcome some of the potential underlying barriers that might exist when involving the Latino immigrant families in obesity treatment and prevention.
Rapid assembly of multilayer microfluidic structures via 3D-printed transfer molding and bonding
Authors: Glick Casey C. , Srimongkol Mitchell T. , Schwartz Aaron J. , Zhuang William S. , Lin Joseph C. , Warren Roseanne H. , Tekell Dennis R. , Satamalee Panitan A. , Lin Liwei 
Published: November 2016

AbstractA critical feature of state-of-the-art microfluidic technologies is the ability to fabricate multilayer structures without relying on the expensive equipment and facilities required by soft lithography-defined processes. Here, three-dimensional (3D) printed polymer molds are used to construct multilayer poly(dimethylsiloxane) (PDMS) devices by employing unique molding, bonding, alignment, and rapid assembly processes. Specifically, a novel single-layer, two-sided molding method is developed to realize two channel levels, non-planar membranes/valves, vertical interconnects (vias) between channel levels, and integrated inlet/outlet ports for fast linkages to external fluidic systems. As a demonstration, a single-layer membrane microvalve is constructed and tested by applying various gate pressures under parametric variation of source pressure, illustrating a high degree of flow rate control. In addition, multilayer structures are fabricated through an intralayer bonding procedure that uses custom 3D-printed stamps to selectively apply uncured liquid PDMS adhesive only to bonding interfaces without clogging fluidic channels. Using integrated alignment marks to accurately position both stamps and individual layers, this technique is demonstrated by rapidly assembling a six-layer microfluidic device. By combining the versatility of 3D printing while retaining the favorable mechanical and biological properties of PDMS, this work can potentially open up a new class of manufacturing techniques for multilayer microfluidic systems.
Red blood cell phase separation in symmetric and asymmetric microchannel networks: effect of capillary dilation and inflow velocity
Authors: Clavica Francesco , Homsy Alexandra , Jeandupeux Laure , Obrist Dominik 
Published: November 2016

AbstractThe non-uniform partitioning or phase separation of red blood cells (RBCs) at a diverging bifurcation of a microvascular network is responsible for RBC heterogeneity within the network. The mechanisms controlling RBC heterogeneity are not yet fully understood and there is a need to improve the basic understanding of the phase separation phenomenon. In this context, in vitro experiments can fill the gap between existing in vivo and in silico models as they provide better controllability than in vivo experiments without mathematical idealizations or simplifications inherent to in silico models. In this study, we fabricated simple models of symmetric/asymmetric microvascular networks; we provided quantitative data on the RBC velocity, line density and flux in the daughter branches. In general our results confirmed the tendency of RBCs to enter the daughter branch with higher flow rate (Zweifach-Fung effect); in some cases even inversion of the Zweifach-Fung effect was observed. We showed for the first time a reduction of the Zweifach-Fung effect with increasing flow rate. Moreover capillary dilation was shown to cause an increase of RBC line density and RBC residence time within the dilated capillary underlining the possible role of pericytes in regulating the oxygen supply.
Taurine Treatment Modulates Circadian Rhythms in Mice Fed A High Fat Diet
Authors: Figueroa Ana Lucia C. , Figueiredo Hugo , Rebuffat Sandra A. , Vieira Elaine , Gomis Ramon 
Published: November 2016

AbstractClose ties have been made among certain nutrients, obesity, type 2 diabetes and circadian clocks. Among nutrients, taurine has been documented as being effective against obesity and type 2 diabetes. However, the impact of taurine on circadian clocks has not been elucidated. We investigated whether taurine can modulate or correct disturbances in daily rhythms caused by a high-fat diet in mice. Male C57BL/6 mice were divided in four groups: control (C), control + taurine (C+T), high-fat diet (HFD) and HFD + taurine (HFD+T). They were administered 2% taurine in their drinking water for 10 weeks. Mice were euthanized at 6:00, 12:00, 18:00, and 24:00. HFD mice increased body weight, visceral fat and food intake, as well as higher levels of glucose, insulin and leptin, throughout the 24 h. Taurine prevented increments in food intake, body weight and visceral fat, improved glucose tolerance and insulin sensitivity and reduced disturbances in the 24 h patterns of plasma insulin and leptin. HFD downregulated the expression of clock genes Rev-erbα, Bmal1, and Per1 in pancreatic islets. Taurine normalized the gene and protein expression of PER1 in beta-cells, which suggests that it could be beneficial for the correction of daily rhythms and the amelioration of obesity and diabetes.