bluuebunny/crossref_metadata_2025_split huggingface dataset:
Live fate-mapping of joint-associated fibroblasts visualizes expansion of cell contributions during zebrafish fin regeneration
Authors: Tornini Valerie A. , Thompson John D. , Allen Raymond L. , Poss Kenneth D. 
Published: August 2017

ABSTRACT
The blastema is a mass of progenitor cells responsible for regeneration of amputated salamander limbs and fish fins. Previous studies have indicated that resident cell sources producing the blastema contribute lineage-restricted progeny to regenerating tissue. However, these studies have labeled general cell types rather than granular cell subpopulations, and they do not explain the developmental transitions that must occur for distal structures to arise from cells with proximal identities in the appendage stump. Here, we find that regulatory sequences of tph1b, which encodes an enzyme that synthesizes serotonin, mark a subpopulation of fibroblast-like cells restricted to the joints of uninjured adult zebrafish fins. Amputation stimulates serotonin production in regenerating fin fibroblasts, yet targeted tph1b mutations abrogating this response do not disrupt fin regeneration. In uninjured animals, tph1b-expressing cells contribute fibroblast progeny that remain restricted to joints throughout life. By contrast, upon amputation, tph1b+ joint cells give rise to fibroblasts that distribute across the entire lengths of regenerating fin rays. Our experiments visualize and quantify how incorporation into an appendage blastema broadens the progeny contributions of a cellular subpopulation that normally has proximodistal restrictions.
The armadillo protein p0071 controls KIF3 motor transport
Authors: Becher Alexander , Eiseler Tim , Porzner Marc , Walther Paul , Keil René , Bobrovich Susanne , Hatzfeld Mechthild , Seufferlein Thomas 
Published: August 2017

ABSTRACT
We here report a novel function of the armadillo protein p0071 (also known as PKP4) during transport mediated by the KIF3 transport complex. Secretion of chromogranin A and matrix metallopeptidase 9 from pancreatic neuroendocrine tumor cells or pancreatic cancer cells, respectively, was substantially reduced following knockdown of p0071. Vesicle tracking indicated that there was impaired directional persistence of vesicle movement upon p0071 depletion. This suggests a disturbed balance between plus- and minus-end directed microtubule transport in cells lacking p0071. p0071 directly interacts with the KIF3 motor subunit KIF3B. Our data indicate that p0071 also interacts with the kinesin cargo adaptor protein KAP3 (also known as KIFAP3) acting as a stabilizing linker between KIF3B and its KAP3 cargo-binding entity. Thus, p0071 is required for directional vesicle movement and secretion of different KIF3-transported carriers, thereby regulating the transport of intracellular membrane vesicles along microtubules.
Sub-mitochondrial localization of the genetic-tagged mitochondrial intermembrane space-bridging components Mic19, Mic60 and Sam50
Authors: Sastri Mira , Darshi Manjula , Mackey Mason , Ramachandra Ranjan , Ju Saeyeon , Phan Sebastien , Adams Stephen , Stein Kathryn , Douglas Christopher R. , Kim Jiwan John , Ellisman Mark H. , Taylor Susan S. , Perkins Guy A. 
Published: August 2017

ABSTRACT
Each mitochondrial compartment contains varying protein compositions that underlie a diversity of localized functions. Insights into the localization of mitochondrial intermembrane space-bridging (MIB) components will have an impact on our understanding of mitochondrial architecture, dynamics and function. By using the novel visualizable genetic tags miniSOG and APEX2 in cultured mouse cardiac and human astrocyte cell lines and performing electron tomography, we have mapped at nanoscale resolution three key MIB components, Mic19, Mic60 and Sam50 (also known as CHCHD3, IMMT and SAMM50, respectively), in the environment of structural landmarks such as cristae and crista junctions (CJs). Tagged Mic19 and Mic60 were located at CJs, distributed in a network pattern along the mitochondrial periphery and also enriched inside cristae. We discovered an association of Mic19 with cytochrome c oxidase subunit IV. It was also found that tagged Sam50 is not uniformly distributed in the outer mitochondrial membrane and appears to incompletely overlap with Mic19- or Mic60-positive domains, most notably at the CJs.
Emerging functions of the Fanconi anemia pathway at a glance
Authors: Sumpter Rhea , Levine Beth 
Published: August 2017

ABSTRACT
Fanconi anemia (FA) is a rare disease, in which homozygous or compound heterozygous inactivating mutations in any of 21 genes lead to genomic instability, early-onset bone marrow failure and increased cancer risk. The FA pathway is essential for DNA damage response (DDR) to DNA interstrand crosslinks. However, proteins of the FA pathway have additional cytoprotective functions that may be independent of DDR. We have shown that many FA proteins participate in the selective autophagy pathway that is required for the destruction of unwanted intracellular constituents. In this Cell Science at a Glance and the accompanying poster, we briefly review the role of the FA pathway in DDR and recent findings that link proteins of the FA pathway to selective autophagy of viruses and mitochondria. Finally, we discuss how perturbations in FA protein-mediated selective autophagy may contribute to inflammatory as well as genotoxic stress.
Cloning fashion: Uniform gay images in male apparel
Authors: Stines Steven 
Published: August 2017

Abstract
Fashion has often served as a signifier of masculinity, from baroque flamboyance to neoclassical simplicity. Gay men have used fashion to create a recognizable image, sometimes in imitation or exaggeration of aggressively heterosexual attire. Before Stonewall, the gay man was often identified as a ‘Pansy’. After the Second World War, the artist Tom of Finland began presenting a new image of gay men – happy, rambunctious and hypermasculine in appearance, coinciding with the development of biker culture and social groups of gay men who did not identify with the effeminate stereotype. With gay liberation came the ‘Clone’, a series of variations reflecting the concerns of gays, who co-opted apparel and grooming identified with traditionally ‘masculine’ men, including some viewed as oppressors. The 1970s Castro Clone provided a contrast to the disco look. During the 1980s, when men’s fashion took on an androgynous or self-conscious air, the ACT UP Clone originated with AIDS activists using clothes to make a socio-political statement. In the 1990s, gay men became more secure and self-expressive but, arguably, shallower. The new Chelsea Clone look focused on tight clothes on a muscular body, contrasting the weight loss associated with HIV. In the early twenty-first century, gay uniformity declined. A highly muscular physique was seen as the hallmark of the AIDS generation. Straight ‘Metrosexuals’ adopted gay style, and in reaction, gay men turned to a less-polished appearance, again emulating and at times parodying heterosexual male archetypes. As civil rights expand, the visual boundaries of clothing seem to be disappearing.
Identity and the imaginary: Rhetorics of menswear in literature and film
Authors: Kambara Kenneth M. , Deming John 
Published: August 2017

Abstract
We critically examine the use of menswear in literature and film as an expression of Weltanschauung, a view of the world by creatives in the literary and visual arts. While depictions and presentations of menswear serve as rhetorical devices in literature and film, this occurs within a sociocultural meaning system, where the creator not only captures elements of social realities but also serves to influence them. Our enquiry informs how taste is defined through the distinctions made in social processes involving cultural capital through creative production. This involves context-rich analyses of how menswear is used to craft identities and tropes embedded within a historicized imaginary that may have never even existed. Such an examination of menswear as an art form in media allows for a nuanced critical analysis of gender performativity and issues of trajectories of meanings over time. Our theoretical framework builds on the fashion system and cultural reproduction work of Roland Barthes and Pierre Bourdieu, respectively. We use several key case studies of twentieth-century authors and film projects to develop new theory that has implications for understanding menswear as an art form with societal significance, with implications for better understanding gender, identity, culture and the everyday praxis of individuals and institutions.
New issues on measurement of B-type natriuretic peptides
Authors: Clerico Aldo , Zaninotto Martina , Passino Claudio , Plebani Mario 
Published: August 2017

Abstract
The measurement of the active hormone of B-type natriuretic peptide (BNP) system actually has several analytical limitations and difficulties in clinical interpretations compared to that of inactive peptide N-terminal proBNP (NT-proBNP) because of the different biochemical and pathophysiological characteristics of two peptides and quality specifications of commercial immunoassay methods used for their measurement. Because of the better analytical characteristics of NT-proBNP immunoassays and the easier pathophysiological and clinical interpretations of variations of NT-proBNP levels in patients with heart failure (HF), some authors claimed to measure the inactive peptide NT-proBNP instead of the active hormone BNP for management of HF patients. The measurement of the active peptide hormone BNP gives different, but complementary, pathophysiological and clinical information compared to inactive NT-proBNP. In particular, the setup of new more sensitive and specific assays for the biologically active peptide BNP1-32 should give better accurate information on circulating natriuretic activity. In conclusion, at present time, clinicians should accurately consider both the clinical setting of patients and the analytical characteristics of BNP and NT-proBNP immunoassays in order to correctly interpret the variations of natriuretic peptides measured by commercially available laboratory methods, especially in patients treated with the new drug class of angiotensin receptor-neprilysin inhibitors.
Electrochemical investigation of corrosion and repassivation of structural aluminum alloys under permanent load in bending
Authors: Ferri Michele , Trueba Monica , Trasatti Stefano P. , Cabrini Marina , Conte Antonietta Lo 
Published: August 2017

AbstractThis work reports an electrochemical investigation of corrosion and repassivation in NaCl solutions of structural Al 7075-T6 and Al 2024-T3 as a function of permanent load in bending by means of single-cycle anodic polarization. Experimental variables other than the load level were the extent of corrosion, chloride ion concentration and initial pH of the test solution, in addition to the pre-exposure in the aggressive environment and of the viscosity of the test solution for Al 7075-T6. The susceptibility to local stress during corrosion and repassivation depends on the alloy microstructure and corrosion mechanisms. In the case of Al 2024-T3, the mechanical activation is driven by cathodically controlled dissolution of this alloy at open circuit in concentrated NaCl, being indicative of a chemomechanical effect. Conversely, for Al 7075-T6, the effect of applied load is better discerned from the repassivation response. Film rupture/formation sequence and related interfacial (electro)chemical processes determine the stress-enhanced metastable repassivation of this alloy.
On symplectic semifield spreads of PG(5,q
2),
q odd
Authors: Marino Giuseppe , Pepe Valentina 
Published: August 2017

Abstract
We prove that there exist exactly three non-equivalent symplectic semifield spreads of

PG
⁡

(
5
,

q
2

)

{\operatorname{PG}(5,q^{2})}

, for

q
2

>

2
⋅

3
8

{q^{2}>2\cdot 3^{8}}

odd, whose associated semifield has center containing

𝔽
q

{\mathbb{F}_{q}}

. Equivalently, we classify, up to isotopy, commutative semifields of order

q
6

{q^{6}}

, for

q
2

>

2
⋅

3
8

{q^{2}>2\cdot 3^{8}}

odd, with middle nucleus containing

𝔽

q
2

{\mathbb{F}_{q^{2}}}

and center containing

𝔽
q

{\mathbb{F}_{q}}

.
Positive solutions for nonlinear nonhomogeneous parametric Robin problems
Authors: Papageorgiou Nikolaos S. , Rădulescu Vicenţiu D. , Repovš Dušan D. 
Published: August 2017

Abstract
We study a parametric Robin problem driven by a nonlinear nonhomogeneous differential operator and with a superlinear Carathéodory reaction term.
We prove a bifurcation-type theorem for small values of the parameter.
Also, we show that as the parameter

λ
>
0

{\lambda>0}

approaches zero, we can find positive solutions with arbitrarily big and arbitrarily small Sobolev norm.
Finally, we show that for every admissible parameter value, there is a smallest positive solution

u
λ
*

{u^{*}_{\lambda}}

of the problem, and we investigate the properties of the map

λ
↦

u
λ
*

{\lambda\mapsto u^{*}_{\lambda}}

.
FS-coalgebras and crossed coproducts
Authors: Chen Yuanyuan , Wang Zhongwei , Zhang Liangyun 
Published: August 2017

Abstract
In this paper, we introduce FS-coalgebras, which provide solutions
of FS-equations and also solution of
braid equations considered by Caenepeel, Militaru and Zhu.
FS-coalgebras are constructed by using
FS-equations and Harrison cocycles.
As applications, we prove that every bialgebra
H is an FS-bialgebra if and only if there is a
two-sided integral α in

H
∗

{H^{\ast}}

such that

ε
⁢

(
α
)

=
1

{\varepsilon(\alpha)=1}

, and we show that
the crossed coproduct

H
R

{H^{R}}

introduced by the Harrison cocycle R is an
FS-coalgebra when

(
H
,
R
)

{(H,R)}

is a finite-dimensional quasitriangular Hopf
algebra or a Long copaired bialgebra.
The Use of PET-CT in Rheumatology
Authors: Ng Ray Sin-Ngai 
Published: August 2017

Abstract
Positron emission tomography (PET) is a sensitive imaging tool that gives quantitative measure of underlying inflammation. Computed tomography (CT) scan used in combination with PET further helps to delineate the anatomical structure. PET-CT can be helpful for the early diagnosis of rheumatic diseases by pattern recognition, but its role in disease monitoring still needs further evaluation. It is not a fast track solution for all because of different sensitivity and specificity to different diseases, relative high cost, and radiation exposure to the patients.
Language ideologies in a Uyghur comedy sketch: the comedy sketch Chüshenmidim ‘I don’t understand’ and the importance of Sap Uyghur
Authors: Cabras Giulia 
Published: August 2017

AbstractUyghur, a Turkic language spoken mostly in the Xinjiang Uyghur Autonomous Region of the People’s Republic of China, is at present undergoing changes in usage. The spread of Standard Chinese promoted by the national government and the growing Han population are contributing to the Sinicization of Uyghur and shaping new language practices. Language-related issues are therefore a common topic in the Uyghur community, in intellectual discourse as well as in daily conversation. This article analyses a Uyghur comedy sketch entitled
Influence of topical iodine-containing antiseptics used during delivery on recall rate of congenital hypothyroidism screening program
Authors: Valizadeh Majid , Moezzi Farzaneh , Khavassi Zohreh , Movahedinia Mohammad , Mazloomzadeh Seideh , Mehran Ladan 
Published: August 2017

AbstractBackground:The proportion of newborns recalled during neonatal screening programs for congenital hypothyroidism (CH) varies substantially by country and may be higher in settings where povodine iodine (PVP-I) is used during delivery. We assessed this hypothesis by substituting PVP-I for chlorhexidine (CHL) and evaluated the reduction in the recall rate of the Irainian newborn screening program.Methods:This study investigated 2282 neonates of mothers admitted to a local hospital for delivery between December 2012 and October 2013. We measured thyorid stimulating hormone (TSH) levels in heel-prick blood specimens of infants, aged between 3 and 5 days, born to mothers who received PVP-I (phase I) and those who received CHL after withdrawal of PVP-I from obstetric procedures (phase II). Then we compared the median TSH levels and the recall rate based on a TSH level ≥5 mU/L.Results:Of 2282 cases, 1094 infants were born to mothers exposed to PVP-I during phase I (PVP-I group) and 1188 ones were born to mothers exposed to chlorhexidine in phase II (CHL group); 6.56% of the PVP-I group and 1.91% of the CHL group were recalled later during screening (p<0.001). The median TSH level was significantly higher in the PVP-I group compared to the CHL group (1.35 vs. 1.00, p<0.001).Conclusions:Replacement of iodine-containing antiseptics by iodine-free ones, during delivery resulted in a significant reduction in the recall rate of the Iranian screening program for CH.
Earnings Surprise, Portfolio Inertia and Stock Price Volatility
Authors: Huang Shunwu , Chang Wang , Zheng Lan 
Published: August 2017

AbstractFrom the perspective of the mediation effect, this paper investigates whether institutional investors adjust their portfolios according to the listed companies earnings surprise. We find that the portfolio adjustments by institutional investors exert the mediation effect on the relationship between earnings surprise and stock price volatility. Institutional investors actively manage their portfolios in the rising market, which induces the stock price volatility; while they less adjust their portfolio in the falling market, the volatility declines. This paper helps understand the role of institutional investors in the fluctuation of stock prices, and provides a new basis for decision making of regulatory administration.
A New Fruit Fly Optimization Algorithm Based on Differential Evolution
Authors: Zhang Dabin , Ye Jia , Zhou Zhigang , Luan Yuqi 
Published: August 2017

Abstract
In order to overcome the problem of low convergence precision and easily relapsing into local extremum in fruit fly optimization algorithm (FOA), this paper adds the idea of differential evolution to fruit fly optimization algorithm so as to optimizing and a algorithm of fruit fly optimization based on differential evolution is proposed (FOADE). Adding the operating of mutation, crossover and selection of differential evolution to FOA after each iteration, which can jump out local extremum and continue to optimize. Compared to FOA, the experimental results show that FOADE has the advantages of better global searching ability, faster convergence and more precise convergence.
Early-Age Running Enhances Activity of Adult-Born Dentate Granule Neurons Following Learning in Rats
Authors: Shevtsova Olga , Tan Yao-Fang , Merkley Christina M. , Winocur Gordon , Wojtowicz J. Martin 
Published: August 2017

AbstractCognitive reserve, the brain’s capacity to draw on enriching experiences during youth, is believed to protect against memory loss associated with a decline in hippocampal function, as seen in normal aging and neurodegenerative disease. Adult neurogenesis has been suggested as a specific mechanism involved in cognitive (or neurogenic) reserve. The first objective of this study was to compare learning–related neuronal activity in adult-born versus developmentally born hippocampal neurons in juvenile male rats that had engaged in extensive running activity during early development or reared in a standard laboratory environment. The second objective was to investigate the long-term effect of exercise in rats on learning and memory of a contextual fear (CF) response later in adulthood. These aims address the important question as to whether exercise in early life is sufficient to build a reserve that protects against the process of cognitive aging. The results reveal a long-term effect of early running on adult-born dentate granule neurons and a special role for adult-born neurons in contextual memory, in a manner that is consistent with the neurogenic reserve hypothesis.
PARAMETER POPULASI UDANG DOGOL (Metapenaeus ensis) DAN UDANG WINDU (Penaeus monodon) DI LAUT ARAFURA
Authors: Suman Ali , Prisantoso Budi Iskandar , Kembaren Duranta D. 
Published: August 2017

Sumber daya udang di perairan Arafura merupakan salah satu modal menuju kemakmuran bagi bangsa, apabila dikelola secara berkelanjutan. Kajian dinamika populasi udang, merupakan salah satu dasar utama dalam merumuskan pengelolaan tersebut menuju pemanfaatan sumber daya yang lestari. Tujuan penelitian ini adalah untuk mengetahui dinamika populasi udang dogol dan udang windu di perairan Arafura dan sekitarnya. Penelitian dilakukan dari bulan Januari 2013 sampai dengan Nopember 2013 dan analisis dilakukan dengan menggunakan FAO-ICLARM Fisheris Stok Assessment Tools (FISAT). Hasil penelitian menunjukkan bahwa laju pertumbuhan (K) udang dogol sebagai 1,33 per tahun dan panjang karapas maksimum (L) sebagai 52,0 mm. Untuk udang windu didapatkan nilai K sebagai 1,45 per tahun dan nilai L sebagai 62,5 mm. Laju kematian total (Z) udang dogol sebagai 4,79 per tahun, laju kematian karena penangkapan (F) dan laju kematian alami (M) masing-masing 2,91 per tahun dan 1,88 per tahun. Untuk udang windu didapatkan nilai Z sebagai 6,13 per tahun, nilai F dan nilai M masing-masing 4,24 dan 1,89 per tahun. Laju pengusahaan (E) udang dogol 0,61 per tahun dan nilai E udang windu sebagai 0,69 per tahun. Tingkat pemanfaatan sudah berada dalam tahapan overfishing dan perlu dilakukan pengurangan jumlah upaya 22% untuk udang dogol dan 38% untuk udang windu.Shrimp resources within Arafura Sea if under sustainably management it would contribute a significant role as a source of nation welfare. Scientific advice on population dynamic are required as an input to support an apropriate fisheries management. The purpose of the study was to identify population parameters of the endeavour shrimp and tiger shrimp in Arafura Sea. Study on the population dynamic of endeavour shrimp and king tiger prawn were conducted in Arafura Sea based on data collected during period of survey, January 2013 to November 2013. The analysis is using the FAO-ICLAM Fisheries Stock Assessment Tools (FiSAT). Result showed that the growth parameter of endeavour shrimp was 1.33/year with maximum carapace length (L) of 52.0 mm. Instantenous total mortality (Z) and natural mortality (M) were 4.79/year and 1.88/year, respectively. While fishing mortality (F) and exploitation rate (E) of endeavour shrimp respectively were 2.91/year and 0.61/year. The growth parameter of king tiger prawn was 1.45/year with maximum carapace length (L) of 62.5 mm. Instantenous total mortality (Z) and natural mortality (M) were 6.13/year and 1.89/year, respectively. While fishing mortality (F) and exploitation rate (E) of king tiger prawn respectively were 4.24/year and 0.69/year. The exploitation rate of endeavour shrimp and king tiger prawn in Arafura Sea was overfishing. It was, therefore, recommended that fishing effort of 22% the endeavour shrimp and 38% king tiger prawn in that waters should be reduced in the next year.