bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between spinopelvic measurements and patient-reported outcome scores in patients with multiple myeloma of the spine
Authors: Yu H. M. , Malhotra K. , Butler J. S. , Patel A. , Sewell M. D. , Li Y. Z. , Molloy S. 
Published: September 2016

Aims Patients with multiple myeloma (MM) develop deposits in the spine which may lead to vertebral compression fractures (VCFs). Our aim was to establish which spinopelvic parameters are associated with the greatest disability in patients with spinal myeloma and VCFs. Patients and Methods We performed a retrospective cross-sectional review of 148 consecutive patients (87 male, 61 female) with spinal myeloma and analysed correlations between spinopelvic parameters and patient-reported outcome scores. The mean age of the patients was 65.5 years (37 to 91) and the mean number of vertebrae involved was 3.7 (1 to 15). Results The thoracolumbar region was most commonly affected (109 patients, 73.6%), and was the site of most posterior vertebral wall defects (47 patients, 31.8%). Poorer Oswestry Disability Index scores correlated with an increased sagittal vertical axis (p = 0.006), an increased number of VCFs (p = 0.035) and sternal involvement (p = 0.012). Poorer EuroQol visual analogue scale scores correlated with posterior vertebral wall defects in the thoracolumbar region (p = 0.012). The sagittal vertical axis increased with the number of fractures and kyphosis in the thoracolumbar (p = 0.009) and lumbar (p < 0.001) regions. Conclusions In MM, patients with VCFs have poorer clinical scores at presentation in the presence of sagittal imbalance. Outcome is particularly affected by multiple fractures in the thoracolumbar and lumbar regions and by failure to prevent kyphosis. Patients with MM should be screened for spinal lesions early. Cite this article: Bone Joint J 2016;98-B:1234–9.
Prior bariatric surgery may decrease the rate of re-operation and revision following total hip arthroplasty
Authors: Watts C. , Martin J. R. , Houdek M. , Abdel M. , Lewallen D. , Taunton M. 
Published: September 2016

Aims We compared the outcome of total hip arthroplasty (THA) in obese patients who previously underwent bariatric surgery and those who did not, in a matched cohort study. Patients and Methods There were 47 THAs in the bariatric group (42 patients), and 94 THAs in the comparison group (92 patients). The mean age of the patients was 57 years in both groups (24 to 79) and 57% of the patients in both groups were women. The mean time between bariatric surgery and THA was five years (four months to 12 years) in the bariatric group. The mean follow-up after THA was three years (2 to 9). Results The mean BMI improved from 49.7 kg/m2 (35 to 75) prior to bariatric surgery to 35.3 kg/m2 (21 to 49) at the time of THA (p < 0.001). Patients in the comparison group had an increased risk of re-operation (Hazard Ratio (HR) 3.2; 95% confidence intervals (CI) 1.3 to 9.5, p = 0.01) and revision (HR 5.4; 95% CI 1.5 to 34.5, p = 0.01) when compared with the bariatric group. Conclusion Patients had a dramatic improvement in BMI after bariatric surgery and those with prior bariatric surgery had a lower risk of re-operation and revision in the short- and mid-term after a subsequent THA. Larger prospective studies are required before it can be concluded that this extra surgery should be advised in these patients. Cite this article: Bone Joint J 2016;98-B:1180–4.
What is a Bristow-Latarjet procedure?
Authors: Cowling P. D. , Akhtar M. A. , Liow R. Y. L. 
Published: September 2016

ObjectivesA variety of operative techniques have been described as under the term ‘Bristow-Latarjet’ procedure. This review aims to define the original procedure, and compare the variation in techniques described in the literature, assessing any effect on clinical outcomes.Materials and MethodsA systematic review of 24 studies was performed to compare specific steps of the technique (coracoid osteotomy site, subscapularis approach, orientation and position of coracoid graft fixation and fixation method, additional labral and capsular repair) and detect any effect this variability had on outcomes.ResultsOverall recurrence rate was 5.36% (2.94% to 43%). Half of the studies performed the procedure for recurrent shoulder instability, with only five studies documenting glenoid bone loss as an indication: 12 studies used the procedure as the primary surgical intervention for recurrent instability. No change in outcome was noted when examining variation in the coracoid osteotomy site, the fixation site on the scapular neck, the fixation method or whether a capsular repair was also performed. Performing a horizontal split in subscapularis may preserve external rotation compared with performing a tenotomy.ConclusionsThis is the first review to examine various operative techniques of the Bristow-Latarjet procedure, and their effect on outcome. We found that other than the approach through subscapularis, outcome was independent of the surgical technique, and depended more on patient selection. We would commend future publications on this procedure to provide a detailed description of the surgical technique, and as a minimum present rates of recurrence as an outcome measure. Cite this article: Bone Joint J 2016;98-B:1208–14.
Lipids contribute to epigenetic control via chromatin structure and functions
Authors: Zhdanov Renad , Schirmer Eric C. , Venkatasubramani Anuroop V. , Kerr Alastair R. W. , Mandrou Elena , Rodriguez-Blanco Giovanny , Kagansky Alexander 
Published: September 2016

Abstract
Isolated cases of experimental evidence over the last few decades have shown that, where specifically tested, both prokaryotes and eukaryotes have specific lipid species bound to nucleoproteins of the genome. In vitro, some of these lipid species exhibit stoichiometric association with DNA polynucleotides with differential affinities toward certain secondary and tertiary structures. Hydrophobic interactions with inner nuclear membrane could provide attractive anchor points for lipid-modified nucleoproteins in organizing the dynamic genome and accordingly there are precedents for covalent bonds between lipids and core histones and, under certain conditions, even DNA. Advances in biophysics, functional genomics, and proteomics in recent years brought about the first sparks of light that promises to uncover some coherent new level of the epigenetic code governed by certain types of lipid–lipid, DNA–lipid, and DNA-protein–lipid interactions among other biochemical lipid transactions in the nucleus. Here, we review some of the older and more recent findings and speculate on how critical nuclear lipid transactions are for individual cells, tissues, and organisms.
Alkaline Pretreatment of Sweet Sorghum Bagasse for Bioethanol Production
Authors: Sudiyani Yanni , Triwahyuni Eka , Muryanto Muryanto , Burhani Dian , Waluyo Joko , Sulaswaty Anny , Abimanyu Haznan 
Published: September 2016

Lignocellulosic material, which consist mainly of cellulose, hemicelluloses and lignin, are among the most promising renewable feedstocks for the production of energy and chemicals. The bagasse residue of sweet sorghum can be utilized as raw material for alternative energy such as bioethanol. Bioethanol production consists of pretreatment, saccharification, fermentation and purification process. The pretreatment process was of great importance to ethanol yield. In the present study, alkaline pretreatment was conducted using a steam explosion reactor at 1300C with concentrations of NaOH 6, and 10% (kg/L) for 10, and 30 min. For ethanol production separated hydrolysis and fermentation (SHF) and simultaneous saccharification and fermentation (SSF) process were conducted with 30 FPU of Ctec2 and Htec2 enzyme and yeast of Saccharomyces cerevisiae. The results showed that maximum cellulose conversion to total glucose plus xylose were showed greatest with NaOH 10% for 30 min. The highest yield of ethanol is 96.26% and high concentration of ethanol 66.88 g/L were obtained at SSF condition during 48 h process. Using SSF process could increase yields and concentration of ethanol with less energy process. Article History: Received January 16th 2016; Received in revised form May 25th 2016; Accepted June 28th 2016; Available onlineHow to Cite This Article: Sudiyani, Y., Triwahyuni, E., Muryanto, Burhani, D., Waluyo, J. Sulaswaty, A. and Abimanyu, H. (2016) Alkaline Pretreatment of Sweet Sorghum Bagasse for Bioethanol Production. Int. Journal of Renewable Energy Development, 5(2), 113-118.http://dx.doi.org/10.14710/ijred.5.2.113-118
Performance characteristics of mix oil biodiesel blends with smoke emissions
Authors: Mohite Sanjay , Kumar Sudhir , Maji Sagar 
Published: September 2016

Fossil fuel resources are being depleted day by day and its use affects the environment adversely. Renewable energy is one of the alternate for sustainable development and biodiesel is one of the suitable alternate which can replace the diesel. The major hurdles in the successful commercialization of biodiesel are high feedstock cost and conversion technology to reduce viscosity. The choice of raw material and biodiesel production method must depend upon techno-economical view. There are some specific regions for different types of oil availability. It is therefore required to produce biodiesel from the mixture of oils to fulfill the requirements of energy demand in a particular country according to its suitability and availability of feedstock. Karanja and Linseed crops are abundantly available in India. Biodiesel was produced from a mixture of Karanja and Linseed oils by alkaline transesterification. In this experimental study, biodiesel blends of 10%, 20% and 30% were used with diesel in a diesel engine at a constant speed of 1500 rpm with varying brake powers (loads) from 0.5 kW to 3.5kW to evaluate brake thermal efficiency, brake specific fuel consumption, brake specific energy consumption, exhaust gas temperature, mechanical efficiency, volumetric efficiency, air fuel ratio and smoke opacity. They were compared with diesel and found satisfactory. BTE was found to be 28.76% for B10 at 3.5kW load. Smoke opacity was also found to be reduced with all blends. Smoke opacity was found to be reduced up to 10.23% for B10 biodiesel blend as compared to that of diesel at 3.5kW. Experimental investigation has revealed that biodiesel produced from a mixture of Karanja and Linseed oils can be successfully used in diesel engines without any engine modification and B10 was found to be an optimum biodiesel blend in terms of brake thermal efficiency. Article History: Received April 14th 2016; Received in revised form June 25th 2016; Accepted July 10th 2016; Available onlineHow to Cite This Article: Mohite. S, Kumar, S. & Maji, S. (2016) Performance characteristics of mix oil biodiesel blends with smoke emissions. Int. Journal of Renewable Energy Development, 5(2), 163-170.http://dx.doi.org/10.14710/ijred.5.2.163-170
MPPT Schemes for PV System under Normal and Partial Shading Condition: A Review
Authors: Sameeullah Malik , Swarup Akhilesh 
Published: September 2016

The photovoltaic system is one of the renewable energy device, which directly converts solar radiation into electricity. The I-V characteristics of PV system are nonlinear in nature and under variable Irradiance and temperature, PV system has a single operating point where the power output is maximum, known as Maximum Power Point (MPP) and the point varies on changes in atmospheric conditions and electrical load. Maximum Power Point Tracker (MPPT) is used to track MPP of solar PV system for maximum efficiency operation. The various MPPT techniques together with implementation are reported in literature. In order to choose the best technique based upon the requirements, comprehensive and comparative study should be available. The aim of this paper is to present a comprehensive review of various MPPT techniques for uniform insolation and partial shading conditions. Furthermore, the comparison of practically accepted and widely used techniques has been made based on features, such as control strategy, type of circuitry, number of control variables and cost. This review work provides a quick analysis and design help for PV systems. Article History: Received March 14, 2016; Received in revised form June 26th 2016; Accepted July 1st 2016; Available onlineHow to Cite This Article: Sameeullah, M. and Swarup, A. (2016). MPPT Schemes for PV System under Normal and Partial Shading Condition: A Review. Int. Journal of Renewable Energy Development, 5(2), 79-94.http://dx.doi.org/10.14710/ijred.5.2.79-94
Winner of the 2016 Lewis Fry Richardson Award, Paul Collier: Clarity and Compassion in the Study of Civil War
Authors: Gates Scott , Skrede Gleditsch Kristian , Shortland Anja 
Published: September 2016

Abstract
The award committee has chosen Paul Collier as the winner of the 2016 Lewis Fry Richardson Award in particular in recognition of his contributions to the study of civil war. His famous paper on “Greed and grievance in civil war” – published with Anke Hoeffler in 2004, but circulating in draft form since the late 1990s – has been cited over 1000 times in the Web of Science as of mid-July 2016, and has over 5000 citations in Google Scholar. The jury also highlighted the key role of Collier’s work reviving academic research on civil war in the late 1990s, the broader impact of the World Bank group led by Collier in spurring advances in the field as well as stimulating important data collection efforts, as well as his central role in popularizing insights of academic research to a broader audience.
Regio- and diastereoselective synthesis of (E)-3-(2-aminochromen-4-yl)-6-aryl-substituted fulvenes
Authors: Koz Gamze , Şahin Onur , Coşkun Necdet 
Published: September 2016

Abstract
A practical base-catalyzed route was developed for the regio- and diastereoselective synthesis of (E)-3-aminochromene-6-aryl-disubstituted fulvenes in high yields up to 94% starting with the Michael addition of cyclopentadiene to 2-iminochromenes in the key step.
Hybrid Interventional Treatment of Iatrogenic Innominate Artery Aneurysm in a Child
Authors: Paczkowski Konrad , Haponiuk Ireneusz , Chojnicki Maciej , Brzezińska-Rajszys Grażyna 
Published: September 2016

An iatrogenic aneurysm of an innominate artery is an extremely rare complication, especially in children. Nevertheless, this pathology was diagnosed in a child given palliative care with chronic respiratory insufficiency and a history of encephalitis requiring permanent ventilation at home via a tracheal tube.<br />A nine-year-old girl with colitis ulcerosa and a history of hemorrhagic encephalitis, with chronic home ventilation therapy, was admitted in an emergency setting because of massive bleeding from the upper respiratory tract and the area surrounding the tracheotomy. Repeated tamponade with topically applied thrombin, and administration of tranexamid acid and cyclonamine appeared ineffective Because of a life-threatening condition and unknown origin of massive bleeding, the child was referred for cardiac catheterization with aortography before qualifying for surgery, with the option of alternative interventional treatment. An alternative option with PTFE-coated stent direct implantation into the brachiocephalic trunk from a peripheral vascular approach was performed. The girl was discharged home after a short recovery. Her chronic home ventilation was continued without additional problems.<br />Stenting of a brachiocephalic trunk aneurysm with a PTFE-coated stent appeared to be a safe and effective treatment of massive bleeding from the respiratory tract, with its main advantage of avoiding the risk of a classic surgical approach in a palliatively treated patient.
Pedagogía, una disciplina indisciplinada: Límites de un debate y sus perspectivas ético políticas
Authors: Gómez-Torres Juan Rafael 
Published: September 2016

The present study aims to develop a rupture of the classical linear matrix about the concept of pedagogy. The proposal restates the idea of pedagogy within an interconnection of different perspectives and knowledge about reality as well. In order to reach that, the vision of pedagogy as a rebellious discipline is proposed. The colonialist and separatist boundaries that characterize pedagogy are discussed. Therefore, the concept of indiscipline as an alternative which resists the educational system is presented, and the new idea of pedagogy as an act of thinking-feeling-doing is analyzed.
Nuo „aukso legendos“ iki „šventųjų gyvenimų“
Authors: Jakulis Martynas 
Published: September 2016

Apie Gitos Drungilienės daktaro disertaciją „LDK katalikiškoji hagiografija: recepcija, sklaida ir šventųjų kulto bruožai XIV a. pabaigoje – XVII a. pradžioje“ ir jos gynimą
Toward Better Pain Management: The Development of a “Pain Stewardship Program” in a Tertiary Children’s Hospital
Authors: Brenn B. Randall , Choudhry Dinesh K. , Sacks Karen , Como-Fluehr Sandra , Strain Robert 
Published: September 2016

OBJECTIVE:
Despite increased focus on pediatric pain, uncontrolled pain is still a problem for hospitalized pediatric inpatients. A program was designed to find patients with uncontrolled pain and develop a framework to oversee their pain management. This report details the development of a pain stewardship program with data from the first year of its activity.

METHODS:
Hospitalized inpatients in a tertiary care pediatric center in the mid-Atlantic region were included in the study. Pain scores are recorded every 4 hours in the hospital electronic health record. A report was constructed to find all patients with an average pain score ≥7 in the preceding 12 hours. The charts of these patients were reviewed by our anesthesia pain service, and all patients were grouped into 1 of the following action categories: (1) no action required; (2) telephone call to the patient’s attending physician; (3) one-time consultation; (4) consultation with ongoing management; or (5) patient was already on the anesthesia pain service. Demographic data, pain regimens, and outcomes were recorded in a prospectively collected database.

RESULTS:
There were 843 records on 441 unique patients. Only 22% required action to be taken by the anesthesia pain service. The pain stewardship database revealed that patients with sickle cell disease or abdominal pain required more frequent attention.

CONCLUSIONS:
An electronic health record–based pain stewardship program is an important step in identifying all children in the hospital with undermanaged pain, and it provides a warning system that may improve patient care, outcomes, and satisfaction.
Identification of Fail Points for Discharging Pediatric Patients With New Tracheostomy and Ventilator
Authors: Sobotka Sarah A. , Hird-McCorry Lindsey P. , Goodman Denise M. 
Published: September 2016

BACKGROUND AND OBJECTIVES:
The core mission of the Pulmonary Habilitation Program is to train and prepare caregivers for the care of a ventilated child in the home. It exists within a free-standing children’s hospital. The program is supported by a multidisciplinary staff and serves ∼100 children. Through standardizing electronic documentation with process-specific tracking for the discharge process, the Pulmonary Habilitation Program team sought to identify intervention opportunities for more efficient and effective discharges.

METHODS:
The process of discharge was described using an iterative process, with the multidisciplinary team and discharge milestones noted in the medical chart.

RESULTS:
Several nonmedical factors contribute to prolonged hospital stays, including parent training, approval from the state agency for home care, and staffing of home nursing. Children had median lengths of stay of 141 days (interquartile range, 68 to 177).

CONCLUSIONS:
As a result of this initial investigation, application to the state agency and training for caregivers have been initiated sooner, when a tracheostomy is first placed.
An analysis of vegetation and species diversity patterns in sand dune and gravel desert ecosystem
Authors: Abdi Mahsa , Afsharzadeh Saeed 
Published: September 2016

This study provides an analysis of vegetation and environmental relationships as well as diversity patterns in sand dunes and gravel desert plains of northern Badrud, Iran. A total of 63 species representing 49 genera and 15 families were recorded. The largest families were Asteraceae (22.2 %) and Chenopodiaceae (19.0 %). Therophytes (66.67 %) were the dominant life form. Chronological analysis showed 57.14 % Irano-Turani elements. Data from 60 1.5 2 m² quadrats, selected systematically randomized along three transects, were collected. Both two-way indicator species analysis (TWINSPAN) and cluster analysis using Ward’s method resulted in the recognition of three communities: an Artemisia sieberi community in the center plain with a Shannon-Wiener diversity index of 0.3, a Stipagrostis plumosa - Schismus arabicus community on the lower sand dunes with a Shannon-Wiener diversity index of 0.7, and a Haloxylon ammodendron community on the higher sand dunes with a Shannon-Wiener diversity index of 0.2. Detrended correspondence analysis (DCA), non-metric multidimensional scaling (NMDS), and multi-response permutation procedure (MRPP), confirmed the separation of TWINSPAN groups as well as the heterogeneity of the Artemisia sieberi - Schismus arabicus community, suggesting a distinct group with Artemisia sieberi and Schismus arabicus as the dominant species. Vegetation environmental analysis by means of multivariate techniques of principal component analysis (PCA) and canonical correspondence analysis (CCA) indicated that very coarse gravel has a strong negative effect on diversity and a negative effect on species cover percentage. Bare ground showed a highly positive effect on diversity variables. Soil analysis suggests final seral stages of succession towards severe desertification.
Cerebrospinal fluid rhinorrhoea: an overview of endoscopic multilayer repair
Authors: Shoeb Mohammed , Mhashal Shashikant , Gite Vinod , Bhargava Samir 
Published: September 2016

<p class="abstract"><strong>Background:</strong> A cerebrospinal fluid (CSF) rhinorrhoea occurs when there is communication between the subarachnoid space and the nasal cavity. CSF rhinorrhoea commonly occurs following head trauma (fronto-basal skull fractures), as a result of intracranial surgery or spontaneously. The aim of our article was to emphasize the importance of endonasal endoscopic surgery using multilayer autograft technique.</p><p class="abstract"><strong>Methods:</strong> A total of 08 cases of CSF rhinorrhoea were treated. A retrospective study was undertaken to analyze the characteristics of 08 patients. After detailed otorhinolaryngoscopic examination, diagnostic nasal endoscopy and radiological evaluation by CT and MRI, all underwent endonasal endoscopic surgery. This article reviews the causes, diagnosis and treatment of CSF leakage of cases done with a 0 degree 4 mm sinoscope using fascia lata septal cartilage and fat as a graft material. </p><p class="abstract"><strong>Results:</strong> The defects as large as 1.5 cm could be safely treated with this technique. The overall success rate of endoscopic repair for CSF rhinorrhoea has been 100%.</p><p><strong>Conclusions:</strong> Endonasal approach is less morbid compared with external approach. Endoscopic surgery gives better visualization.</p>
El pediatra ante la discapacidad de niños y adolescentes
Authors: Flores Arizmendi Karla Adney , Gómez Puente Lidia del Carmen 
Published: September 2016

Los niños son el grupo social más vulnerable y los que tienen discapacidad se encuentran con una doble desventaja: la de ser niños y la de tener una discapacidad.En la mayoría de las ocasiones, el pediatra es el primer contacto de salud de las personas con discapacidad. En nuestra formación profesional no se ha incluido el tema discapacidad como un problema social y sanitario prevalente, por lo que en la mayoría de los casos nos enfrentamos ante un panorama totalmente desconocido.