bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the meaningfulness of healthcare organizations: a multiple case study
Authors: Palumbo Rocco , Annarumma Carmela , Musella Marco 
Published: May 2017

Purpose
Patient empowerment has been variously depicted as a new paradigm inspiring the patient-provider relationship. To the authors’ knowledge, scholars have focused most of their attention on patient enablement. Alternatively, the ability of health care organizations to establish a comfortable and co-creating partnership with the patients has been overlooked. In an attempt to fill this gap, the purpose of this paper is to delve into the meaningfulness of health care organizations, embracing the “organizational health literacy” perspective.

Design/methodology/approach
In line with the exploratory nature of this research, a multiple case study approach was taken. It concerned three large public hospitals operating within the Italian National Health Service. The meaningfulness of health care organizations was investigated drawing on the organizational health literacy construct.

Findings
The health care organizations were unaware of several crucial issues to improve their meaningfulness. Problematic organizational health literacy was found to prevent patient involvement and to negatively affect the quality of interaction between the patients and the health care professionals.

Practical implications
Inadequate organizational health literacy impoverishes the ability of health care organizations to empower the patients and to engage them in value co-creation. The institutional purposes of empowering the patients and involving them in the provision of care require tailored interventions intended to improve organizational meaningfulness.

Originality/value
This is one of the first attempts to examine the meaningfulness of health care organizations through the lenses of organizational health literacy. Both quality of care and health outcomes are expected to benefit from the enhancement of organizational health literacy.
Modeling errors in parts supply processes for assembly lines feeding
Authors: Caputo Antonio Casimiro , Pelagagge Pacifico Marcello , Salini Paolo 
Published: May 2017

Purpose
The purpose of this paper is to develop a quantitative model to assess probability of errors and errors correction costs in parts feeding systems for assembly lines.

Design/methodology/approach
Event trees are adopted to model errors in the picking-handling-delivery-utilization of materials containers from the warehouse to assembly stations. Error probabilities and quality costs functions are developed to compare alternative feeding policies including kitting, line stocking and just-in-time delivery. A numerical case study is included.

Findings
This paper confirms with quantitative evidence the economic relevance of logistic errors (LEs) in parts feeding processes, a problem neglected in the existing literature. It also points out the most frequent or relevant error types and identifies specific corrective measures.

Research limitations/implications
While the model is general purpose, conclusions are specific to each applicative case and are not generalizable, and some modifications may be required to adapt it to specific industrial cases. When no experimental data are available, human error analysis should be used to estimate event probabilities based on underlying modes and causes of human error.

Practical implications
Production managers are given a quantitative decision tool to assess errors probability and errors correction costs in assembly lines parts feeding systems. This allows better comparing of alternative parts feeding policies and identifying corrective measures.

Originality/value
This is the first paper to develop quantitative models for estimating LEs and related quality cost, allowing a comparison between alternative parts feeding policies.
Open and closed knowledge sourcing
Authors: Ham Juyeon , Choi Byounggu , Lee Jae-Nam 
Published: May 2017

PurposeMany studies have investigated the relationship between the adoption of open innovation and performance in large firms. However, limited research is available with regard to the use of open innovation in small and medium enterprises (SMEs). SMEs are important because of their contribution to innovation in almost all economies. The purpose of this paper is to extend the current literature by focusing on SMEs. Using complementarity and knowledge-based theories, this study develops three hypotheses to identify the effect of knowledge sourcing approaches for innovation on SMEs’ innovation performance.Design/methodology/approachSurveys collected from 196 SMEs in Korea were analyzed using the supermodularity function to test the hypotheses.FindingsResults indicate that an external knowledge-oriented approach has no significant effect, whereas an internal knowledge-oriented (i.e. closed) approach has a positive effect on innovation performance. Interestingly, this study found that open innovation has a negative effect on SMEs’ innovation performance (i.e. both internal knowledge-oriented and external knowledge-oriented approaches have a substitutive relationship).Originality/valueThis study sheds new light on open innovation and knowledge management research by identifying the relationship between knowledge sourcing approaches for innovation, and innovation performance in SMEs. Practical implications highlight that open innovation could impede SMEs’ innovation performance.
Europe leads the way in assistive robots for the elderly
Authors: Bogue Robert 
Published: May 2017

Purpose
This paper aims to provide details of European research projects and product developments involving robots that can assist the ageing population.

Design/methodology/approach
Following an introduction, the role of assistive robots and research into the nature of the human–robot interaction are considered. The paper then discusses a selection of European research projects and a number of companies producing or developing assistive robots. Finally, brief conclusions are drawn.

Findings
In recognition of the fact that the growing, ageing population has needs that place an unsustainable burden on carers and healthcare providers, Europe is investing heavily in assistive robots. Many European Union-funded, collaborative projects have been conducted and several continue today which build on the extensive body of earlier research. Significant progress is being made, and assistive robot research has moved on from purely technological developments to field trials involving real people in realistic environments. Several products exist or are at an advanced stage of development and have often benefited or arisen from these projects. Europe is in a very strong position to capitalise on this emerging market opportunity.

Originality/value
This provides a detailed insight into European assistive robot development activities.
Toward a unified model of human information behavior: an equilibrium perspective
Authors: Liu Jiqun 
Published: May 2017

Purpose
The purpose of this paper is to build a unified model of human information behavior (HIB) for integrating classical constructs and reformulating the structure of HIB theory.

Design/methodology/approach
This paper employs equilibrium perspective from partial equilibrium theory to conceptualization and deduction, starting from four basic assumptions.

Findings
This paper develops two models to incorporate previous HIB research approaches into an equilibrium-analysis-oriented information supply-demand (ISD) framework: first, the immediate-task/problem-based and everyday life information-seeking (ELIS)-sense-making approaches are incorporated into the short-term ISD model; second, the knowledge-construction-oriented and ability-based HIB research approaches are elaborated by the long-term ISD model. Relations among HIB theories are illustrated via the method of graphical reasoning. Moreover, these two models jointly reveal the connection between information seeking in immediate problematic situations and long-term ability improvement.

Originality/value
The equilibrium framework enables future research to explore HIB from three perspectives: stages: group the classical concepts (e.g. anomalous state of knowledge, uncertainty) into different stages (i.e. start state, process, goal state) and see how they interact with each other within and across different stages; forces: explore information behaviors and information-related abilities as information supply and demand forces, and see how different forces influence each other and jointly motivate people to pursue the equilibriums between outside world and mental model; and short term and long term: study the connections between short-term information seeking and long-term ability improvement at both theoretical and empirical levels.
“A wound that has been festering since 2007”
Authors: Luyt Brendan 
Published: May 2017

Purpose
The Burma/Myanmar naming controversy on Wikipedia stands as an exemplary debate at least in terms of the politeness and civility of discourse. It was also one of the longer running debates on Wikipedia beginning almost at the same time as the creation of the article in 2003. But this debate has other lessons for those interested in one of the world’s key pieces of information infrastructure. The paper aims to discuss these issues.

Design/methodology/approach
The author’s approach to the study of the Wikipedia talk pages devoted to the Burma/Myanmar naming controversy is qualitative in nature and explores the debate over sources through textual analysis.

Findings
Editors brought to their work a number of underlying assumptions including the primacy of the nation-state and the nature of a “true” encyclopedia. These were combined with a particular interpretation of neutral point of view (NPOV) policy that unnecessarily prolonged the debate and, more importantly, would have the effect, if widely adopted, of reducing Wikipedia’s potential to include multiple perspectives on any particular topic.

Originality/value
The study clearly shows how editors tend to uncritically reproduce the dominant assumptions of their societies. When combined with positivist readings of NPOV policy, this has grave implications for Wikipedia’s potential to open up representation to a wider set of knowledge producers and perspectives. Much of this potential cannot be realized if the assumptions of editors, especially their flawed understanding of NPOV, cannot be challenged effectively.
A “think piece” on intelligence, investigation and prosecution
Authors: Fitzpatrick David 
Published: May 2017

Purpose
The purpose of this paper is to expose the failure of the criminal justice system of England and Wales to provide an effective response to widespread fraud and to point to sources from which a new doctrine may be created. The author’s approach draws on public sources, in particular, recent Home Office publications, the work of the House of Commons Home Affairs Committee and studies undertaken by the Mayor of London’s offices in 2014/2015.

Design/methodology/approach
The paper uses a critical assessment of the criminal justice system based on the author’s own experience as a fraud prosecutor.

Findings
Among the findings is that, while the failings of the current system have been apparent for some years, the extent and depth of the same failings have not been publicly realised, nor sufficiently acknowledged by the authorities. It has become obvious that the traditional response of the criminal justice system, when employed against fraud, will fail for want of anything corresponding to the resources required. A new doctrine will emerge as the Proceeds of Crime Act 2002 is revised and more flexibly employed. The Criminal Finances Bill also holds much promise, in particular, with its new offences akin to money laundering and the provision of powers of investigation at a significantly lower level of command among investigators. However, there remains an apparent reluctance in law enforcement to explain its methodology or to support reform, which would allow a fuller sharing of intelligence and appreciations of threats posed by fraud derived from intelligence with the financial services sector and the victim public.

Originality/value
The value of the paper is derived from the author’s long experience as a fraud prosecutor and as an adviser to the government, on fraud and organised crime, in a closely related jurisdiction with similar problems, but where greater success has been achieved, namely, Hong Kong.
Classification shifting: impact of firm life cycle
Authors: Nagar Neerav , Sen Kaustav 
Published: May 2017

Purpose
This paper aims to examine whether firms in the decline stage of lifecycle manipulate core or operating income through misclassification of operating expenses as income-decreasing special items.

Design/methodology/approach
The sample comprises of firms from an emerging market, India with data from 1996 to 2011. The paper uses the methodology given in McVay’s (2006) work and multiple regressions.

Findings
Managers of Indian firms also engage in classification shifting, primary incentive being the desire to avoid reporting of operating losses. Furthermore, the use of classification shifting is dependent upon the stage of lifecycle in which firm is in. Specifically, firms in the decline stage of lifecycle are more likely to use classification shifting to avoid reporting of operating losses.

Practical implications
The paper sheds light on a critical phase of the firm lifecycle, decline, which increases the possibility of the use of classification shifting, an earnings management technique which is tough to detect. Firms in decline, thus, may be trying to fool the investors who are infusing capital to save the company from going bankrupt; regulators, who are likely to focus less on troubled firms; and auditors, who may not be expecting core income manipulation in such firms.

Originality/value
The paper extends the literature on classification shifting and presents first evidence that such shifting is more likely to take place during the decline phase of firm lifecycle.
Adenovirus vector expressing keratinocyte growth factor using CAG promoter impairs pulmonary function of mice with elastase‐induced emphysema
Authors: Oki Hiroshi , Yazawa Takuya , Baba Yasuko , Kanegae Yumi , Sato Hanako , Sakamoto Seiko , Goto Takahisa , Saito Izumu , Kurahashi Kiyoyasu 
Published: May 2017

ABSTRACTPulmonary emphysema impairs quality of life and increases mortality. It has previously been shown that administration of adenovirus vector expressing murine keratinocyte growth factor (KGF) before elastase instillation prevents pulmonary emphysema in mice. We therefore hypothesized that therapeutic administration of KGF would restore damage to lungs caused by elastase instillation and thus improve pulmonary function in an animal model. KGF expressing adenovirus vector, which prevented bleomycin‐induced pulmonary fibrosis in a previous study, was constructed. Adenovirus vector (1.0 × 109 plaque‐forming units) was administered intratracheally one week after administration of elastase into mouse lungs. One week after administration of KGF–vector, exercise tolerance testing and blood gas analysis were performed, after which the lungs were removed under deep anesthesia. KGF‐positive pneumocytes were more numerous, surfactant protein secretion in the airspace greater and mean linear intercept of lungs shorter in animals that had received KGF than in control animals. Unexpectedly, however, arterial blood oxygenation was worse in the KGF group and maximum running speed, an indicator of exercise capacity, had not improved after KGF in mice with elastase‐induced emphysema, indicating that KGF‐expressing adenovirus vector impaired pulmonary function in these mice. Notably, vector lacking KGF‐expression unit did not induce such impairment, implying that the KGF expression unit itself may cause the damage to alveolar cells. Possible involvement of the CAG promoter used for KGF expression in impairing pulmonary function is discussed.
Hypertension Induced by Tyrosine‐Kinase Inhibitors for the Treatment of Renal Cell Carcinoma in Hemodialysis Patients: A Single‐Center Experience and Review of the Literature
Authors: Nakai Kentaro , Fujii Hideki , Kono Keiji , Goto Shunsuke , Nishi Shinichi 
Published: May 2017

AbstractMalignancy is a major cause of mortality in dialysis patients. Although molecular‐targeted anticancer drugs, including tyrosine‐kinase inhibitors, are used for advanced renal cell carcinoma treatment, there are few reports on their effectiveness and safety in dialysis patients. Renal cell carcinoma dialysis patients treated at our hospital from 2010 to 2013 participated in this study. Thirteen patients were treated with tyrosine‐kinase inhibitors and 15 patients with surgery only (control group). During treatment, blood pressure changes and dry weight reduction tended to be greater in the tyrosine‐kinase inhibitor group than in controls. More intensive management of hypertension was necessary in the tyrosine‐kinase inhibitor group than in the controls. Renal cell carcinoma treatment by tyrosine‐kinase inhibitors increased blood pressure in hemodialysis patients. We should prevent and manage hypertension carefully by adjusting antihypertensive drugs and dry weight in renal cell carcinoma patients.
CEO Power and Relative Performance Evaluation
Authors: Dikolli Shane S. , Diser Viktoria , Hofmann Christian , Pfeiffer Thomas 
Published: May 2017

AbstractWe model relative performance evaluation (RPE) when a Chief Executive Officer (CEO) has the power to opportunistically influence the design of RPE by choosing the weight on an index‐based peer group or by customizing the selection of peers comprising a peer group. A powerful CEO compares the benefits of reducing common risk affecting his compensation with the benefits of receiving a higher bonus by economizing on expected peer‐group performance. As a consequence, the Board of Directors (BoD) is less likely to use RPE. Our analytical model yields hypotheses predicting that powerful CEOs choose to reduce common risk only partially and that BoDs choose to not implement RPE if expected peer performance is sufficiently high. Our model has further empirical implications in (i) providing new interpretations of tests for detecting strong‐form and weak‐form RPE in the presence of powerful CEOs, and (ii) suggesting a new empirical measure of CEO power with a focus on the delegation of RPE decision rights.
Drivers of present and lifetime natural resource use in a tropical biodiversity hotspot
Authors: Reuter K. E. , Sewall B. J. , Di Minin E. 
Published: May 2017

AbstractEffective biodiversity conservation requires an understanding of the drivers of natural resource use. Few studies, however, have examined how motivations of natural resource users and attributes of local social organizations affect resource extraction over time. We aimed to identify which characteristics of individuals (taboos, food security, resource‐related income), groups (village size, ease of access to education, proximity to park), and institutions (presence of enforcement mechanisms) best predicted use of multiple types of natural resources near a protected area during the past 1.5 years and during respondents’ lifetimes. Data were collected in 2013 via semi‐structured interviews with 360 people across ten villages along the perimeter of Ankarana National Park (northern Madagascar). All recent and lifetime uses of natural resources examined were higher in villages close to the park and for respondents with a history of earning money from extracting natural resources. In addition, individuals with ancestral meat‐related taboos were less likely to have extracted natural resources over their lifetime, while individuals who recently consumed meat were more likely to have extracted natural resources over the past 1.5 years. All other variables were less important in explaining the use of natural resources. The results highlight that some drivers can be consistently important in predicting natural resource use and that simple models can have relatively high explanatory power even in the context of the (sometimes) illegal extraction of five different types of natural resources.
Repetitive Supra‐Physiological Shear Stress Impairs Red Blood Cell Deformability and Induces Hemolysis
Authors: Horobin Jarod T. , Sabapathy Surendran , Simmonds Michael J. 
Published: May 2017

AbstractThe supra‐physiological shear stress that blood is exposed to while traversing mechanical circulatory assist devices affects the physical properties of red blood cells (RBCs), impairs RBC deformability, and may induce hemolysis. Previous studies exploring RBC damage following exposure to supra‐physiological shear stress have employed durations exceeding clinical instrumentation, thus we explored changes in RBC deformability following exposure to shear stress below the reported “hemolytic threshold” using shear exposure durations per minute (i.e., duty‐cycles) reflective of that employed by circulatory assist devices. Blood collected from 20 male donors, aged 18–38 years, was suspended in a viscous medium and exposed to an intermittent shear stress protocol of 1 s at 100 Pa, every 60 s for 60 duty‐cycles. During the remaining 59 s/min, the cells were left at stasis until the subsequent duty‐cycle commenced. At discrete time points (15/30/45/60 duty‐cycles), an ektacytometer measured RBC deformability immediately after shear exposure at 100 Pa. Plasma‐free hemoglobin, a measurement of hemolysis, was quantified via spectrophotometry. Supra‐physiological shear stress impaired RBC properties, as indicated by: (1) decreased maximal elongation of RBCs at infinite shear stress following 15 duty‐cycles (P <0.05); (2) increased real‐time RBC deformability during application of the supra‐physiological shear stress protocol (100 Pa) following exposure to 1 duty‐cycle (F (1.891, 32.15) = 12.21, P = 0.0001); and (3) increased plasma‐free hemoglobin following 60 duty‐cycles (P < 0.01). The present study indicates that exposure of RBCs to short‐term, repeated supra‐physiological shear stress, impairs RBC deformability, with the extent of impairment exacerbated with each duty‐cycle, and ultimately precipitates hemolysis.
Impact of genotype on leukaemic transformation in polycythaemia vera and essential thrombocythaemia
Authors: Alvarez‐Larrán Alberto , Senín Alicia , Fernández‐Rodríguez Concepción , Pereira Arturo , Arellano‐Rodrigo Eduardo , Gómez Montse , Ferrer‐Marin Francisca , Martínez‐López Joaquín , Camacho Laura , Colomer Dolors , Angona Anna , Navarro Blanca , Cervantes Francisco , Besses Carlos , Bellosillo Beatriz , Hernández‐Boluda Juan Carlos 
Published: May 2017

SummaryThe influence of driver mutations on leukaemic transformation was analysed in 1747 patients with polycythaemia vera or essential thrombocythaemia. With a median follow‐up of 7·2 years, 349 patients died and 62 progressed to acute leukaemia or myelodysplastic syndrome. Taking death as a competing risk, CALR genotype was associated with a lower risk of transformation [subdistribution hazard ratio (SHR): 0·13, 95% confidence interval (CI): 0·2–0·9, P = 0·039], whereas JAK2 V617F showed borderline significance for higher risk (SHR: 2·05, 95% CI: 0·9–4·6, P = 0·09). Myelofibrotic transformation increased leukaemic risk, except in CALR‐mutated patients. Next generation sequencing of 51 genes at the time of transformation showed additional mutations (median number: 3; range: 1–5) in 25 out of 29 (86%) assessable cases. Mutations (median: 1; range: 1–3) were detected in 67% of paired samples from the chronic phase. Leukaemia appeared in a JAK2 V617F negative clone in 17 (58%) cases, eleven of them being previously JAK2 V617F‐positive. JAK2 V617F‐mutated leukaemia was significantly associated with complex karyotype and acquisition of TP53 mutations, whereas EZH2 and RUNX1 mutations were more frequent in JAK2 V617F‐negative leukaemia. Survival was longer in JAK2 V617F‐unmutated leukaemia (343 days vs. 95 days, P = 0·003). In conclusion, CALR genotype is associated with a lower risk of leukaemic transformation. Leukaemia arising in a JAK2 V617F‐negative clone is TP53 independent and shows better survival.