bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytic Method for the Estimation of Initial Producing GOR for a Horizontal Well With a Gas Cap
Authors: Langdon Ian S. 
Published: February 2016

Abstract
Since the late 1980's there has been significant primary development of thin heavy oil and bitumen pools with horizontal wells in Western Canada. These pools were previously not developable as they did not have high enough transmissivity for economic vertical well development. Horizontal wells permitted primary development within this resource base by providing an alternative production geometry from which low transmissivity reservoirs could be economically produced. As development proceeds in this resource it is apparent that the producing Gas Oil Ratio (GOR) characteristic of such wells is not typical of vertical wells in conventional oils. For saturated heavy oil and bitumen reservoirs producing on solution gas drive the producing GOR's tend to be much higher than the initial solution GOR (Rs;) for the heavy oil or bitumen produced. In the event the wellbore intersects primary or secondary gas caps, the producing GOR can be dramatically higher than the solution GOR (Rs). This paper derives an analytic approach that demonstrates the potential impact on producing GOR of a small gas saturation intersected by a horizontal well in a heavy oil or bitumen.
Sequential Anaerobic/Aerobic Digestion for Enhanced Carbon/Nitrogen Removal and Cake Odor Reduction
Authors: Ahmad Muneer , Denee Marco Abel , Jiang Hao , Eskicioglu Cigdem , Kadota Paul , Gregonia Theresa 
Published: February 2016

ABSTRACT: Anaerobic digestion (AD) has been proven to be an effective process for the treatment of wastewater sludge. However, it produces high levels of ammonia in the digester effluent, which may jeopardize meeting stringent nutrient discharge limits. In this study, the effect of a sequential anaerobic/aerobic (AN/AERO) digestion and a single‐stage conventional AN digestion (as control) was investigated on mixed (primary + secondary) sludge generated by the Annacis Island wastewater treatment plant (WWTP) (BC, Canada). An overall sludge retention time (SRT) of 22.5 days under three different scenarios was chosen based on the current operational SRT of the digesters at the Annacis Island WWTP. The steady state results have shown that sequential AN/AERO digestion configurations achieved up to 11% higher volatile solids (VS) removal and 72% lower ammonia generation over single‐stage conventional AN digestion. Furthermore, sequential AN/AERO system also showed enhanced dewaterability, improved fecal coliform destruction and reduced digested cake odors over control digesters.
Effect of Tolvaptan in Autosomal Dominant Polycystic Kidney Disease by CKD Stage: Results from the TEMPO 3:4 Trial
Authors: Torres Vicente E. , Higashihara Eiji , Devuyst Olivier , Chapman Arlene B. , Gansevoort Ronald T. , Grantham Jared J. , Perrone Ronald D. , Ouyang John , Blais Jaime D. , Czerwiec Frank S. ,   for the TEMPO 3:4 Trial Investigators
Published: February 2016

Background

and objectives The Tolvaptan Efficacy and Safety in Management of Autosomal Dominant Polycystic Kidney Disease and Its Outcomes 3:4 study demonstrated a significant beneficial effect of the vasopressin V2 receptor antagonist tolvaptan on rates of kidney growth and eGFR decline in autosomal dominant polycystic kidney disease (ADPKD). This post hoc analysis was performed to reassess the primary and secondary efficacy endpoints by CKD stage at baseline.

Design, setting, participants, & measurements
In a phase 3, multicenter, double-blind, placebo-controlled, 3-year trial, 1445 patients with ADPKD (age 18–50 years), with total kidney volume (TKV) ≥750 ml and estimated creatinine clearance ≥60 ml/min, were randomly assigned 2:1 to split-dose tolvaptan (45/15, 60/30, or 90/30 mg daily as tolerated) or placebo. The primary endpoint was annualized rate of TKV change. Secondary endpoints included a composite endpoint of time to multiple composite ADPKD-related events (worsening kidney function, kidney pain, hypertension, and albuminuria) and rate of kidney function decline.

Results
Tolvaptan reduced annualized TKV growth by 1.99%, 3.12%, and 2.61% per year (all P<0.001; subgroup–treatment interaction, P=0.17) and eGFR decline by 0.40 in CKD1 (P=0.23), 1.13 in CKD2 (P<0.001) and 1.66 ml/min per 1.73 m2 per year in CKD3 (P<0.001) with a trend for a positive subgroup-treatment interaction (P=0.07) across CKD1, CKD2 and CKD3. ADPKD-related events were less frequent in tolvaptan recipients than in placebo recipients among those with CKD1 (hazard ratio [HR], 0.83; 95% confidence interval [95% CI], 0.70–0.98; P=0.03) and those with CKD 3 (HR, 0.71; 95% CI, 0.57–0.89; P=0.003), but not among those with CKD2 (HR, 1.02; 95% CI, 0.85–1.21; P=0.86). Aquaresis-related adverse events (more frequent in the tolvaptan group) and ADPKD-related adverse events (more frequent in the placebo group) were not associated with CKD stage. Hypernatremia events in tolvaptan-treated patients with CKD3 and plasma aminotransferase elevations in tolvaptan-treated patients across CKD stages 1–3 occurred more frequently than in placebo recipients.

Conclusions
This post hoc analysis suggests clinically similar beneficial effects of tolvaptan in ADPKD across CKD stages 1–3.
BORO as a Foundation to Enterprise Ontology
Authors: de Cesare Sergio , Partridge Chris 
Published: February 2016

ABSTRACT
Modern business organizations experience increasing challenges in the development and evolution of their enterprise systems. Typical problems include legacy re-engineering, systems integration/interoperability, and the architecting of the enterprise. At the heart of all these problems is enterprise modeling. Many enterprise modeling approaches have been proposed in the literature with some based on ontology. Few however adopt a foundational ontology to underpin a range of enterprise models in a consistent and coherent manner. Fewer still take data-driven re-engineering as their natural starting point for modeling. This is the approach taken by Business Object Reference Ontology (BORO). It has two closely intertwined components: a foundational ontology and a re-engineering methodology. These were originally developed for the re-engineering of enterprise systems and subsequently evolved into approaches to enterprise architecture and systems integration. Together these components are used to systematically unearth reusable and generalized business patterns from existing data. Most of these patterns have been developed for the enterprise context and have been successfully applied in several commercial projects within the financial, defense, and oil and gas industries. BORO's foundational ontology is grounded in philosophy and its metaontological choices (including perdurantism, extensionalism, and possible worlds) follow well-established theories. BORO's re-engineering methodology is rooted in the philosophical notion of grounding; it emerged from the practice of deploying its foundational ontology and has been refined over the last 25 years. This paper presents BORO and its application to enterprise modeling.
GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
Authors: Halden Thea A.S. , Egeland Erlend J. , Åsberg Anders , Hartmann Anders , Midtvedt Karsten , Khiabani Hassan Z. , Holst Jens J. , Knop Filip K. , Hornum Mads , Feldt-Rasmussen Bo , Jenssen Trond 
Published: February 2016

OBJECTIVEDevelopment of posttransplantation diabetes (PTDM) is characterized by reduced insulin secretion and sensitivity. We aimed to investigate whether hyperglucagonemia could play a role in PTDM and to examine the insulinotropic and glucagonostatic effects of the incretin hormone glucagon-like peptide 1 (GLP-1) during fasting and hyperglycemic conditions, respectively.RESEARCH DESIGN AND METHODSRenal transplant recipients with (n = 12) and without (n = 12) PTDM underwent two separate experimental days with 3-h intravenous infusions of GLP-1 (0.8 pmol/kg/min) and saline, respectively. After 1 h of infusion, a 2-h hyperglycemic clamp (fasting plasma glucose + 5 mmol/L) was established. Five grams of arginine was given as an intravenous bolus 10 min before termination of the clamp.RESULTSFasting concentrations of glucagon (P = 0.92) and insulin (P = 0.23) were similar between the groups. In PTDM patients, glucose-induced glucagon suppression was significantly less pronounced (maximal suppression from baseline: 43 ± 12 vs. 65 ± 12%, P &lt; 0.001), while first- and second-phase insulin secretion were significantly lower. The PTDM group also exhibited a significantly lower insulin response to arginine (P = 0.01) but similar glucagon and proinsulin responses compared with control subjects. In the preclamp phase, GLP-1 lowered fasting plasma glucose to the same extent in both groups but reduced glucagon only in PTDM patients. During hyperglycemic clamp, GLP-1 reduced glucagon concentrations and increased first- and second-phase insulin secretion in both groups.CONCLUSIONSPTDM is characterized by reduced glucose-induced insulin secretion and attenuated glucagon suppression during a hyperglycemic clamp. Similar to the case in type 2 diabetes, GLP-1 infusion seems to improve (insulin) or even normalize (glucagon) these pathophysiological defects.
Registries in Clinical Epidemiology: the European Surveillance System on Contact Allergies (ESSCA)
Authors: Schnuch A. , Wilkinson M. , Dugonik A. , Dugonik B. , Ganslandt T. , Uter W. 
Published: February 2016

SummaryBackground: Disease registries rely on consistent electronic data capturing (EDC) pertinent to their objectives; either by using existing electronic data as far as available, or by implementing specific software solutions.Objectives: To describe the current practice of an international disease registry (European Surveillance System on Contact Allergies, ESSCA, www.essca-dc.org) against different state of the art approaches for EDC.Methods: Since 2002, ESSCA is collecting data, currently from 53 departments in 12 countries. Departmental EDC software ranges from spreadsheets to comprehensive “patch test software” based on a relational database. In the Erlangen data centre, such diverse data is imported, converted to a common format, quality checked and pooled for scientific analyses.Results: Feed-back to participating departments for quality control is provided by standardised reports. Varying author teams publish scientific analyses addressing the objective of contact allergy surveillance.Conclusions: Although ESSCA represents a historically grown, heterogeneous network and not one unified approach to EDC, some of its features have contributed to its viability in the last 12 years and may be useful to consider for similar investigator-initiated networks.
DETECTION EFFICIENCY OF ASTEROID SURVEYS
Authors: Tricarico Pasquale 
Published: February 2016

ABSTRACT
A comprehensive characterization of the detection efficiency of nine of the major asteroid surveys that have been active over the past two decades is presented. The detection efficiency is estimated on a nightly basis by comparing the detected asteroids with the complete catalog of known asteroids propagated to the same observing epoch. Results include a nightly estimate of the detection efficiency curves as a function of apparent magnitude and apparent velocity of the asteroids, as well as a cumulative analysis to estimate the overall performance of each survey. The limiting magnitude distribution is estimated for each survey, and it is then modeled as a function of telescope aperture to obtain an estimate over a wide range of apertures.
FLARE STARS—A FAVORABLE OBJECT FOR STUDYING MECHANISMS OF NONTHERMAL ASTROPHYSICAL PHENOMENA
Authors: Oks E. , Gershberg R. E. 
Published: February 2016

ABSTRACT
We present a spectroscopic method for diagnosing a low-frequency electrostatic plasma turbulence (LEPT) in plasmas of flare stars. This method had been previously developed by one of us and successfully applied to diagnosing the LEPT in solar flares. In distinction to our previous applications of the method, here we use the latest advances in the theory of the Stark broadening of hydrogen spectral lines. By analyzing observed emission Balmer lines, we show that it is very likely that the LEPT was developed in several flares of AD Leo, as well as in one flare of EV Lac. We found the LEPT (though of different field strengths) both in the explosive/impulsive phase and at the phase of the maximum, as well as at the gradual phase of the stellar flares. While for solar flares our method allows diagnosing the LEPT only in the most powerful flares, for the flare stars it seems that the method allows revealing the LEPT practically in every flare. It should be important to obtain new and better spectrograms of stellar flares, allowing their analysis by the method outlined in the present paper. This can be the most favorable way to the detailed understanding of the nature of nonthermal astrophysical phenomena.
SEARCHING FOR BINARY Y DWARFS WITH THE GEMINI MULTI-CONJUGATE ADAPTIVE OPTICS SYSTEM (GeMS)
Authors: Opitz Daniela , Tinney C. G. , Faherty Jacqueline K. , Sweet Sarah , Gelino Christopher R. , Kirkpatrick J. Davy 
Published: February 2016

ABSTRACT
The NASA Wide-field Infrared Survey Explorer (WISE) has discovered almost all the known members of the new class of Y-type brown dwarfs. Most of these Y dwarfs have been identified as isolated objects in the field. It is known that binaries with L- and T-type brown dwarf primaries are less prevalent than either M-dwarf or solar-type primaries, they tend to have smaller separations and are more frequently detected in near-equal mass configurations. The binary statistics for Y-type brown dwarfs, however, are sparse, and so it is unclear if the same trends that hold for L- and T-type brown dwarfs also hold for Y-type ones. In addition, the detection of binary companions to very cool Y dwarfs may well be the best means available for discovering even colder objects. We present results for binary properties of a sample of five WISE Y dwarfs with the Gemini Multi-Conjugate Adaptive Optics System. We find no evidence for binary companions in these data, which suggests these systems are not equal-luminosity (or equal-mass) binaries with separations larger than ∼0.5–1.9 AU. For equal-mass binaries at an age of 5 Gyr, we find that the binary binding energies ruled out by our observations (i.e., 1042 erg) are consistent with those observed in previous studies of hotter ultra-cool dwarfs.
META-CLASSIFICATION FOR VARIABLE STARS
Authors: Pichara Karim , Protopapas Pavlos , León Daniel 
Published: February 2016

ABSTRACT
The need for the development of automatic tools to explore astronomical databases has been recognized since the inception of CCDs and modern computers. Astronomers already have developed solutions to tackle several science problems, such as automatic classification of stellar objects, outlier detection, and globular clusters identification, among others. New scientific problems emerge, and it is critical to be able to reuse the models learned before, without rebuilding everything from the beginning when the sciencientific problem changes. In this paper, we propose a new meta-model that automatically integrates existing classification models of variable stars. The proposed meta-model incorporates existing models that are trained in a different context, answering different questions and using different representations of data. A conventional mixture of expert algorithms in machine learning literature cannot be used since each expert (model) uses different inputs. We also consider the computational complexity of the model by using the most expensive models only when it is necessary. We test our model with EROS-2 and MACHO data sets, and we show that we solve most of the classification challenges only by training a meta-model to learn how to integrate the previous experts.
THE CURIOUS CASE OF ELEMENTAL ABUNDANCE DIFFERENCES IN THE DUAL HOT JUPITER HOSTS WASP-94A AND B*
Authors: Teske Johanna K. , Khanal Sandhya , Ramírez Ivan 
Published: February 2016

ABSTRACT
Binary stars provide an ideal laboratory for investigating the potential effects of planet formation on stellar composition. Assuming that the stars formed in the same environment/from the same material, any compositional anomalies between binary components might indicate differences in how material was sequestered in planets, or accreted by the star in the process of planet formation. We present here a study of the elemental abundance differences between WASP-94A and B, a pair of stars that each host a hot Jupiter exoplanet. The two stars are very similar in spectral type (F8 and F9), and their ∼2700 au separation suggests that their protoplanetary disks were likely not influenced by stellar interactions, but WASP-94Ab’s orbit—misaligned with the host star spin axis and likely retrograde—points toward a dynamically active formation mechanism, perhaps different from that of WASP-94Bb, which is not misaligned and has a nearly circular orbit. Based on our high-quality spectra and strictly relative abundance analysis, we detect a depletion of volatiles (∼−0.02 dex, on average) and enhancement of refractories (∼0.01 dex) in WASP-94A relative to B (standard errors are ∼0.005 dex). This is different from every other published case of binary host star abundances, in which either no significant abundance differences are reported or there is some degree of enhancement in all elements, including volatiles. Several scenarios that may explain the abundance trend are discussed, but none can be definitively accepted or rejected. Additional high-contrast imaging observations to search for companions that may be dynamically affecting the system, as well as a larger sample of binary host star studies, are needed to better understand the curious abundance trends we observe in WASP-94A and B.
DIFFUSE CORONAE IN COSMOLOGICAL SIMULATIONS OF MILKY WAY-SIZED GALAXIES
Authors: Sokołowska A. , Mayer L. , Babul A. , Madau P. , Shen S. 
Published: February 2016

ABSTRACT
We investigate the properties of halo gas using three cosmological “zoom-in” simulations of realistic Milky Way-galaxy analogs with varying sub-grid physics. In all three cases, the mass of hot (T > 106 K) halo gas is ∼1% of the host's virial mass. The X-ray luminosity of two of the runs is consistent with observations of the Milky Way, while the third simulation is X-ray bright and resembles more closely a very massive, star-forming spiral. Hot halos extend to 140 kpc from the galactic center and are surrounded by a bubble of warm-hot (

K) gas that extends to the virial radius. Simulated halos agree well outside 20–30 kpc with the β-model of Miller & Bregman based on O vii absorption and O viii emission measurements. Warm-hot and hot gas contribute up to 80% of the total gas reservoir, and contain nearly the same amount of baryons as the stellar component. The mass of warm-hot and hot components falls into the range estimated for

galaxies. With key observational constraints on the density of the Milky Way corona being satisfied, we show that concealing of the ubiquitous warm-hot baryons, along with the ejection of just 20%–30% of the diffuse gas out of the potential wells by supernova-driven outflows, can solve the “missing baryon problem.” The recovered baryon fraction within 3 virial radii is 90% of the universal value. With a characteristic density of ∼10−4 cm−3 at 50–80 kpc, diffuse coronae meet the requirement for fast and complete ram-pressure stripping of the gas reservoirs in dwarf galaxy satellites.
Vegetation and floristics of a lowland tropical rainforest in northeast Australia
Authors: Tng David , Apgaua Deborah , Campbell Mason , Cox Casey , Crayn Darren , Ishida Françoise , Liddell Michael , Seager Michael , Laurance Susan 
Published: February 2016

Full floristic data, tree demography, and biomass estimates incorporating non-tree lifeforms are seldom collected and reported for forest plots in the tropics. Established research stations serve as important repositories of such biodiversity and ecological data. With a canopy crane setup within a tropical lowland rainforest estate, the 42-ha Daintree Rainforest Observatory (DRO) in Cape Tribulation, northern Australia is a research facility of international significance. We obtained an estimate of the vascular plant species richness for the site, by surveying all vascular plant species from various mature-phase, remnant and open vegetation patches within the site. We also integrate and report the demography and basal areas of trees ≥ 10 cm diameter at breast height (dbh) in a new 1-ha core plot, an extension to the pre-existing forest 1-ha plot under the canopy crane. In addition, we report for the canopy crane plot new demography and basal areas for smaller-size shrubs and treelets subsampled from nine 20 m2 quadrats, and liana basal area and abundance from the whole plot. The DRO site has an estimated total vascular plant species richness of 441 species, of which 172 species (39%) are endemic to Australia, and 4 species are endemics to the Daintree region. The 2 x 1-ha plots contains a total of 262 vascular plant species of which 116 (1531 individuals) are tree species ≥ 10 cm dbh. We estimate a stem basal area of 34.9 m2 ha-1, of which small stems (tree saplings and shrubs &lt;10cm dbh) and lianas collectively contribute c.4.2%. Comparing the stem density-diversity patterns of the DRO forest with other tropical rainforests globally, our meta-analysis shows that DRO forests has a comparatively high stem density and moderate species diversity, due to the influence of cyclones. These data will provide an important foundation for ecological and conservation studies in lowland tropical forest.
We present a floristic checklist, a lifeform breakdown, and demography data from two 1-ha rainforest plots from a lowland tropical rainforest study site. We also present a meta-analysis of stem densities and species diversity from comparable-sized plots across the tropics.
Spécificités de la symbolisation dans les médiations thérapeutiques
Authors: Brun Anne 
Published: February 2016

Les médiations thérapeutiques ont connu un essor considérable ces dernières années. Elles sont souvent pratiquées en groupe, mais encore trop peu par des psychologues et des psychanalystes. À partir de l’exercice d’intervision d’un atelier de peinture rassemblant des patients psychotiques et autistes adultes, l’auteure analyse en quoi la médiation artistique est une psychothérapie analytique, à condition d’être fondée sur l’associativité et le transfert : associativité non verbale autour de la dynamique sensori-motrice et des signifiants formels et prise en compte du transfert sur le médium malléable (matériau, cadre, thérapeute) d’expériences archaïques catastrophiques. À travers les réponses des cliniciens, leur co-éprouvé et leur travail de mise en sens, s’instaure un processus d’émergence de la symbolisation que l’auteure modélise en dégageant notamment une première phase de désymbolisation, pour aboutir à la représentation de figures de réflexivité.
Clivage, fragmentation, agonie psychique : la « pensée clinique » de Sándor Ferenczi
Authors: Bokanowski Thierry 
Published: February 2016

Les apports originaux de Sándor Ferenczi concernant les questions posées par le « traumatique » et le « trauma » lui ont permis de développer une pensée très originale qui, entre autres, marque l’ébauche d’hypothèses et de concepts que l’on retrouve ultérieurement chez certains continuateurs de la pensée freudienne, notamment M. Klein, D.W. Winnicott et W.R. Bion.
La lettre anarchiste
Authors: Isnard Hélène 
Published: February 2016

La lecture de l’œuvre d’Artaud au prisme de la pulsion anarchiste théorisée par N. Zaltzman permet de saisir comment l’expérience-limite, en tant qu’expérience de néantisation du sujet, permet aussi dans le même mouvement la mise en échec de la pulsion de mort. Subvertir et retourner la violence d’emprise de l’autre est alors la seule issue de vie possible, où l’anarchisme travaille à émanciper et à protéger.