bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Systematic Review of Reminiscence Therapy for Older Adults in Taiwan
Authors: Yen Hsin-Yen , Lin Li-Jung 
Published: October 2017

ABSTRACT

Background:
Population aging is an increasing phenomenon in many countries around the world. It has been estimated that more than one quarter of all older adults experience a mental or neurological disorder or disease such as dementia, depression, anxiety, and substance abuse. Reminiscence is a popular treatment for enhancing well-being in older adults. Previous studies have shown that reminiscence therapy improves the cognitive functions, behaviors, and other psychosocial outcomes in older adult patients. The themes and materials that are used in reminiscence treatments for the older adults in Taiwan differ from those used in other countries because of Taiwan’s unique historical background and culture.

Purpose:
The main purpose of the current study was to review systematically the application and outcomes of reminiscence therapy in Taiwan.

Method:
The terms “reminiscence,” “dementia,” “Alzheimer’s disease,” and “Taiwan” were used in an Integrated Resources Search that was conducted at National Taiwan Normal University. Sixteen articles were systematically reviewed using a synthesis of two matrices of experimental designs and intervention designs.

Result:
Reminiscence group sizes ranged between 7 and 12 participants, session frequencies were all once a week for periods lasting between 4 and 16 weeks, and session durations ranged from 30 minutes to 2 hours. The memories of the participants were stimulated using materials dating from their youth such as Taiwanese folk songs, toys, photos, radio programs, newspapers, and food and drinks. In terms of research methodology, most of the studies that were reviewed used quasi-experimental designs without random assignment or control group due to sample size. A minority of the reviewed studies applied the randomized controlled treatment method. Only a few of the studies evaluated indicators in pretest, posttest, and follow-up periods. The results of these studies identified several benefits of reminiscence therapy in Taiwanese older adults, including improvements in cognitive function, anxiety, depressive symptoms, self-esteem, life satisfaction, and personal interaction.

Conclusions:
Reminiscence is a good noninvasive treatment for the prevention and treatment of mental diseases in Taiwanese older adults. Furthermore, reminiscence promotes mental health in older adults. Finally, this study provides recommendations for further study and clinical application of reminiscence therapy in Taiwan.
Acute life-threatening hypoxemia during mechanical ventilation
Authors: Piraino Thomas , Fan Eddy 
Published: October 2017

Purpose of review
To describe current evidence-based practice in the management of acute life-threatening hypoxemia in mechanically ventilated patients and some of the methods used to individualize the care of the patient.

Recent findings
Patients with acute life-threatening hypoxemia will often meet criteria for severe ARDS, for which there are only a few treatment strategies that have been shown to improve survival outcomes. Recent findings have increased our knowledge of the physiological effects of spontaneous breathing and the application of PEEP. Additionally, the use of advanced bedside monitoring has a promising future in the management of hypoxemic patients to fine-tune the ventilator and to evaluate the individual patient response to therapy.

Summary
Treating the patient with acute life-threatening hypoxemia during mechanical ventilation should begin with an evidence-based approach, with the goal of improving oxygenation and minimizing the harmful effects of mechanical ventilation. The use of advanced monitoring and the application of simple maneuvers at the bedside may assist clinicians to better individualize treatment and improve clinical outcomes.
Bovine Colostrum for Preterm Infants in the First Days of Life
Authors: Juhl Sandra Meinich , Ye Xuqiang , Zhou Ping , Li Yanqi , Iyore Elisabeth Omolabake , Zhang Lixia , Jiang Pingping , van Goudoever Johannes B. , Greisen Gorm , Sangild Per Torp 
Published: October 2017

ABSTRACTObjectives:Mother's own milk (MM) is the best nutrition for newborn preterm infants, but is often limited in supply just after birth. Pasteurized human donor milk (DM), and especially preterm infant formula (IF) are less optimal diets than MM. We hypothesized that it is feasible to use bovine colostrum (BC), the first milk from cows, as a supplement to MM, during the first weeks after preterm birth.Methods:In an open‐label, randomized, controlled pilot safety trial, supplementation of MM with BC was compared with DM supplementation (Danish unit) or IF supplementation (Chinese unit). If MM was limited or lacking, BC, DM or IF were given according to local feeding guidelines during the first 14 days of life.Results:Forty infants were included and randomized in Denmark and in China, with gestational ages 29.9 ± 0.4 and 31.1 ± 0.2 weeks, respectively. Infants supplemented with BC received more enteral protein (P < 0.05) and tended to reach full enteral feeding earlier (China only). Eight infants fed BC showed a temporary elevation in plasma tyrosine on day 7, versus 2 infants in the DM/IF groups. There were no differences between diet groups in feeding intolerance or clinical adverse events.Conclusions:Our results indicate that it is feasible to use BC as a supplement to MM during the first weeks of life to increase enteral protein intake in preterm infants. Plasma tyrosine levels may be a good marker for excessive protein intake. A larger randomized trial is required to test the safety and possible short‐ and long‐term clinical benefits of BC supplementation during the first weeks of life for preterm infants.
Holder‐Pasteurized Human Donor Milk
Authors: de Waard Marita , Mank Elise , van Dijk Karin , Schoonderwoerd Anne , van Goudoever Johannes B. 
Published: October 2017

ABSTRACTObjective:When own mother's milk falls short, pasteurized human donor milk is recommended as alternative feeding for preterm infants. Donor milk has to meet the highest safety standards, but its processing and storage is expensive. The recommended storage time of pasteurized donor milk is 3 months. The objective of the present study was to determine whether the frozen storage time of pasteurized donor milk can be extended beyond 3 months without compromising its safety and quality.Methods:For this prospective observational study breast milk samples of 34 unique women, collected between November 2014 and June 2015, were provided by the Dutch Human Milk Bank. Samples were Holder pasteurized within 3 months after expression and stored at −20°C. Analysis of both bacterial growth (by inoculation of milk on a blood and a cysteine‐, lactose‐, and electrolyte‐deficient agar) and fat, crude protein, carbohydrate and energy content of milk (analyzed by infrared spectroscopy) was done monthly during the first 6 months and every 2 months thereafter, up to 1 year postpasteurization.Results:Thirty of 306 (9.8%) follow‐up samples showed bacterial growth when cultured. None of the samples showed sequential contamination with the same strain up to 8 months of frozen storage. No significant decreases in macronutrients and energy content were observed over 8 months.Conclusion:Pasteurized human donor milk can be stored safely for 8 months at −20°C, without compromising its macronutrient and energy content. This longer storage time will reduce disposal of expired donor milk and subsequently reduce costs.
Assessing Lifetime Stress Exposure Using the Stress and Adversity Inventory for Adults (Adult STRAIN): An Overview and Initial Validation
Authors: Slavich George M. , Shields Grant S. 
Published: October 2017

ABSTRACT

Objective
Numerous theories have proposed that acute and chronic stressors may exert a cumulative effect on life-span health by causing biological “wear and tear,” or allostatic load, which in turn promotes disease. Very few studies have directly tested such models, though, partly because of the challenges associated with efficiently assessing stress exposure over the entire life course. To address this issue, we developed the first online system for systematically assessing lifetime stress exposure, called the Stress and Adversity Inventory (STRAIN), and describe its initial validation here.

Methods
Adults recruited from the community (n = 205) were administered the STRAIN, Childhood Trauma Questionnaire—Short Form, and Perceived Stress Scale, as well as measures of socioeconomic status, personality, social desirability, negative affect, mental and physical health complaints, sleep quality, computer-assessed executive function, and doctor-diagnosed general health problems and autoimmune disorders.

Results
The STRAIN achieved high acceptability and was completed relatively quickly (mean = 18 minutes 39 seconds; interquartile range = 12–23 minutes). The structure of the lifetime stress data best fit two latent classes overall and five distinct trajectories over time. Concurrent associations with the Childhood Trauma Questionnaire—Short Form and Perceived Stress Scale were good (r values = .147–.552). Moreover, the STRAIN was not significantly related to personality traits or social desirability characteristics and, in adjusted analyses, emerged as the measure most strongly associated with all six of the health and cognitive outcomes assessed except current mental health complaints (β values = .16–.41; risk ratios = 1.02–1.04). Finally, test-retest reliability for the main stress exposure indices over 2–4 weeks was excellent (r values = .904–.919).

Conclusions
The STRAIN demonstrated good usability and acceptability; very good concurrent, discriminant, and predictive validity; and excellent test-retest reliability.
Incidence of Tuberculosis Among HIV-Positive Individuals Initiating Antiretroviral Treatment at Higher CD4 Counts in the HPTN 071 (PopART) Trial in South Africa
Authors: Bock Peter , Jennings Karen , Vermaak Redwaan , Cox Helen , Meintjes Graeme , Fatti Geoffrey , Kruger James , De Azevedo Virginia , Maschilla Leonard , Louis Francoise , Gunst Colette , Grobbelaar Nelis , Dunbar Rory , Limbada Mohammed , Floyd Sian , Grimwood Ashraf , Ayles Helen , Hayes Richard , Fidler Sarah , Beyers Nulda ,   on behalf of the HPTN 071, PopART team
Published: October 2017

Introduction:
Antiretroviral treatment (ART) guidelines recommend life-long ART for all HIV-positive individuals. This study evaluated tuberculosis (TB) incidence on ART in a cohort of HIV-positive individuals starting ART regardless of CD4 count in a programmatic setting at 3 clinics included in the HPTN 071 (PopART) trial in South Africa.

Methods:
A retrospective cohort analysis of HIV-positive individuals aged ≥18 years starting ART, between January 2014 and November 2015, was conducted. Follow-up was continued until 30 May 2016 or censored on the date of (1) incident TB, (2) loss to follow-up from HIV care or death, or (3) elective transfer out; whichever occurred first.

Results:
The study included 2423 individuals. Median baseline CD4 count was 328 cells/μL (interquartile range 195–468); TB incidence rate was 4.41/100 person-years (95% confidence interval [CI]: 3.62 to 5.39). The adjusted hazard ratio of incident TB was 0.27 (95% CI: 0.12 to 0.62) when comparing individuals with baseline CD4 >500 and ≤500 cells/μL. Among individuals with baseline CD4 count >500 cells/μL, there were no incident TB cases in the first 3 months of follow-up. Adjusted hazard of incident TB was also higher among men (adjusted hazard ratio 2.16; 95% CI: 1.41 to 3.30).

Conclusions:
TB incidence after ART initiation was significantly lower among individuals starting ART at CD4 counts above 500 cells/μL. Scale-up of ART, regardless of CD4 count, has the potential to significantly reduce TB incidence among HIV-positive individuals. However, this needs to be combined with strengthening of other TB prevention strategies that target both HIV-positive and HIV-negative individuals.
Propagation of BOLD activity reveals task-dependent directed interactions across human visual cortex
Authors: Gravel Nicolás , Renken Remco J. , Harvey Ben M. , Deco Gustavo , Cornelissen Frans W. , Gilson Matthieu 
Published: October 2017

AbstractIt has recently been shown that large-scale propagation of blood-oxygen level dependent (BOLD) activity is constrained by anatomical connections and reflects transitions between behavioral states. It remains to be seen, however, if the propagation of BOLD activity can also relate to the brain anatomical structure at a more local scale. Here, we hypothesized that BOLD propagation reflects structured neuronal activity across early visual field maps. To explore this hypothesis, we characterize the propagation of BOLD activity across V1, V2 and V3 using a modeling approach that aims to disentangle the contributions of local activity and directed interactions in shaping BOLD propagation. It does so by estimating the effective connectivity (EC) and the excitability of a noise-diffusion network to reproduce the spatiotemporal covariance structure of the data. We apply our approach to 7T fMRI recordings acquired during resting state (RS) and visual field mapping (VFM). Our results reveal different EC interactions and changes in cortical excitability in RS and VFM, and point to a reconfiguration of feedforward and feedback interactions across the visual system. We conclude that the propagation of BOLD activity has functional relevance, as it reveals directed interactions and changes in cortical excitability in a task-dependent manner.
A hybrid versatile method for state estimation and feature extraction from the trajectory of animal behavior
Authors: Yamazaki Shuhei J. , Ohara Kazuya , Ito Kentaro , Kokubun Nobuo , Kitanishi Takuma , Takaichi Daisuke , Yamada Yasufumi , Ikejiri Yosuke , Hiramatsu Fumie , Fujita Kosuke , Tanimoto Yuki , Yamazoe-Umemoto Akiko , Hashimoto Koichi , Sato Katsufumi , Yoda Ken , Takahashi Akinori , Ishikawa Yuki , Kamikouchi Azusa , Hiryu Shizuko , Maekawa Takuya , Kimura Koutarou D. 
Published: October 2017

ABSTRACTAnimal behavior is the final and integrated output of the brain activity. Thus, recording and analyzing behavior is critical to understand the underlying brain function. While recording animal behavior has become easier than ever with the development of compact and inexpensive devices, detailed behavioral data analysis requires sufficient previous knowledge and/or high content data such as video images of animal postures, which makes it difficult for most of the animal behavioral data to be efficiently analyzed to understand brain function. Here, we report a versatile method using a hybrid supervised/unsupervised machine learning approach to efficiently estimate behavioral states and to extract important behavioral features only from low-content animal trajectory data. As proof of principle experiments, we analyzed trajectory data of worms, fruit flies, rats, and bats in the laboratories, and penguins and flying seabirds in the wild, which were recorded with various methods and span a wide range of spatiotemporal scales—from mm to 1000 km in space and from sub-seconds to days in time. We estimated several states during behavior and comprehensively extracted characteristic features from a behavioral state and/or a specific experimental condition. Physiological and genetic experiments in worms revealed that the extracted behavioral features reflected specific neural or gene activities. Thus, our method provides a versatile and unbiased way to extract behavioral features from simple trajectory data to understand brain function.
NAC-NORmutations in tomato Penjar accessions attenuate multiple metabolic processes and prolong the fruit shelf life
Authors: Kumar Rakesh , Tamboli Vajir , Sharma Rameshwar , Sreelakshmi Yellamaraju 
Published: October 2017

AbstractSeveral Penjar accessions of tomato (Solanum lycopersicum), widely grown in the Mediterranean region, exhibit prolonged shelf life, and harboralcobacamutation with valine-106-aspartic acid substitution in the NAC-NOR protein. To uncover the metabolic basis underlying the prolonged shelf life, we compared four Penjar accessions to Ailsa Craig (AC). Three accessions borealcobacamutation, whereas fourth was a novelNAC-NORallele with only six amino acids in the encoded protein. The cuticle composition among Penjars varied widely during the progression of fruit ripening. All Penjars exhibited delayed ripening, prolonged on-vine and off-vine shelf life, low ethylene emission and carotenoid levels albeit with accession-specific differences. Metabolic profiling revealed shifts in Krebs cycle intermediates, amino acids, and β-aminobutyric acid levels indicating the attenuation of respiration in Penjars during post-harvest storage. The prolonged shelf life of Penjar fruits was associated with a concerted downregulation of a number of cell-wall modifying genes and cell-wall-related metabolites. The accumulation of higher ABA and sucrose levels at the onset of senescence in Penjar fruits likely contribute to reduced water loss. Our analyses reveal that in addition to specialized cuticle composition, the attenuation of various metabolic processes byNAC-NORmutation likely prolongs the shelf life of Penjar fruits.HighlightThe prolonged shelf life of tomato Penjar accessions bearing mutations in NAC-NOR transcription factor appears to be regulated by a combined effect of attenuation of respiration, altered cuticle composition, enhanced ABA and sucrose levels in fruits and downregulation of cell wall modification
Hippocampus, retrosplenial and parahippocampal cortices encode multi-compartment 3D space in a hierarchical manner
Authors: Kim Misun , Maguire Eleanor A. 
Published: October 2017

AbstractHumans commonly operate within 3D environments such as multi-floor buildings and yet there is a surprising dearth of studies that have examined how these spaces are represented in the brain. Here we had participants learn the locations of paintings within a virtual multi-level gallery building and then used behavioural tests and fMRI repetition suppression analyses to investigate how this 3D multi-compartment space was represented, and whether there was a bias in encoding vertical and horizontal information. We found faster response times for within-room egocentric spatial judgments and behavioural priming effects of visiting the same room, providing evidence for a compartmentalised representation of space. At the neural level, we observed a hierarchical encoding of 3D spatial information, with left anterior hippocampus representing local information within a room, while retrosplenial cortex, parahippocampal cortex and posterior hippocampus represented room information within the wider building. Of note, both our behavioural and neural findings showed that vertical and horizontal location information was similarly encoded, suggesting an isotropic representation of 3D space even in the context of a multi-compartment environment. These findings provide much-needed information about how the human brain supports spatial memory and navigation in buildings with numerous levels and rooms.
High-Precision Automated Reconstruction of Neurons with Flood-filling Networks
Authors: Januszewski Michał , Kornfeld Jörgen , Li Peter H. , Pope Art , Blakely Tim , Lindsey Larry , Maitin-Shepard Jeremy , Tyka Mike , Denk Winfried , Jain Viren 
Published: October 2017

AbstractReconstruction of neural circuits from volume electron microscopy data requires the tracing of complete cells including all their neurites. Automated approaches have been developed to perform the tracing, but without costly human proofreading their error rates are too high to obtain reliable circuit diagrams. We present a method for automated segmentation that, like the majority of previous efforts, employs convolutional neural networks, but contains in addition a recurrent pathway that allows the iterative optimization and extension of the reconstructed shape of individual neural processes. We used this technique, which we call flood-filling networks, to trace neurons in a data set obtained by serial block-face electron microscopy from a male zebra finch brain. Our method achieved a mean error-free neurite path length of 1.1 mm, an order of magnitude better than previously published approaches applied to the same dataset. Only 4 mergers were observed in a neurite test set of 97 mm path length.
Fuzzy logic algorithm of hovering control for the quadrotor unmanned aerial system
Authors: Yu Lie , Chen Jia , Tian Yukang , Sun Yunzhou , Ding Lei 
Published: October 2017

Purpose
The purpose of this paper is to present a control strategy which uses two independent PID controllers to realize the hovering control for unmanned aerial systems (UASs). In addition, the aim of using two PID controller is to achieve the position control and velocity control simultaneously.

Design/methodology/approach
The dynamic of the UASs is mathematically modeled. One PID controller is used for position tracking control, while the other is selected for the vertical component of velocity tracking control. Meanwhile, fuzzy logic algorithm is presented to use the actual horizontal component of velocity to compute the desired position.

Findings
Based on this fuzzy logic algorithm, the control error of the horizontal component of velocity tracking control is narrowed gradually to be zero. The results show that the fuzzy logic algorithm can make the UASs hover still in the air and vertical to the ground.

Social implications
The acquired results are based on simulation not experiment.

Originality/value
This is the first study to use two independent PID controllers to realize stable hovering control for UAS. It is also the first to use the velocity of the UAS to calculate the desired position.
The anti-periodic oscillations of shunting inhibitory cellular neural networks with time-varying delays and continuously distributed delays
Authors: Xu Changjin , Li Peiluan 
Published: October 2017

Purpose
The purpose of this paper is to study the existence and exponential stability of anti-periodic solutions of a class of shunting inhibitory cellular neural networks (SICNNs) with time-varying delays and continuously distributed delays.

Design/methodology/approach
The inequality technique and Lyapunov functional method are applied.

Findings
Sufficient conditions are obtained to ensure that all solutions of the networks converge exponentially to the anti-periodic solution, which are new and complement previously known results.

Originality/value
There are few papers that deal with the anti-periodic solutions of delayed SICNNs with the form negative feedback – aij(t)αij(xij(t)).