bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subfascial Primary Breast Augmentation with Fat Grafting: A Review of 156 Cases
Authors: Kerfant Nathalie , Henry Anne-Sophie , Hu Weiguo , Marchac Alexandra , Auclair Eric 
Published: April 2017

Background:
Composite breast augmentation with fat grafting and an implant has become very popular in the past 5 years. This achieves the core volume projection of an implant complemented by the natural appearance and feel of fat. However, no study has looked at the complications and reoperation rates of this technique.

Methods:
A retrospective chart review examined all patients who underwent the combined use of an implant and fat grafting for primary breast augmentation.

Results:
The study identified 156 patients between 2007 and 2013. The mean patient age was 31.7 years and the average body mass index was 18.85 kg/m2. The average implant size was 252 cc. Patients received a mean of 126 cc of fat (range, 30 to 250 cc) in subcutaneous soft tissue. Follow-up averaged 22.25 months (range, 1 to 86 months). The total complication rate was 7.7 percent and the reoperation rate was 9.94 percent. Baker grade II/III contracture was the most common complication [Baker grade II, n = 4 (2.56 percent); Baker grade III, n = 2 (2 percent)], followed by infections [n = 2 (1.28 percent)], hematoma [n = 2 (1.28 percent)], and malrotation [n = 1 (0.64 percent)]. Delayed reoperation was performed in nine patients (9.94 percent) after a mean interval of 31.7 months. Two patients who developed Baker grade III contractures needed surgery to correct the problem. Three cases (1.92 percent) required additional fat grafting for insufficient soft-tissue coverage. The mean volume of fat reinjection was 170 cc.

Conclusions:
Composite breast augmentation is a valuable, stable, reliable technique in breast aesthetic surgery with good, natural-appearing results. It provides long-term aesthetic benefits and avoids the submuscular plane.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Therapeutic, IV.
Two-Dimensional Spoiled Gradient-Recalled Echo Magnetic Resonance Imaging of the Liver Using Respiratory Navigator-Gating Techniques
Authors: Inoue Yusuke , Hata Hirofumi , Matsunaga Keiji , Nakajima Ai , Komi Shotaro , Abe Yutaka , Miyatake Hiroki 
Published: April 2017

Objective
We assessed the feasibility of T1-weighted 2-dimensional spoiled gradient-recalled (2D SPGR) acquisition in steady-state imaging of the liver with various respiratory navigator gating techniques.

Methods
A total of 12 healthy volunteers underwent in-phase and out-of-phase 2D SPGR imaging of the liver during breath-holding and free-breathing. Four techniques for respiratory navigation, 2 conventional navigator techniques and 2 self-navigator techniques, were used for free-breathing imaging.

Results
Good navigator waveforms were obtained in conventional navigation, whereas fluctuations were evident in self navigation. All of the 4 navigator-based methods provided better images in terms of background signals and visual image quality compared with images obtained with no respiratory control. However, differences remained in comparison with breath-holding. Superiority of self-navigation to conventional navigation was not shown.

Conclusions
Navigator-gating techniques improved 2D SPGR images of the liver acquired during free-breathing, suggesting feasibility and beneficial effects, although navigator-based images were still inferior to breath-hold images.
Image Quality and Radiation Exposure Comparison of a Double High-Pitch Acquisition for Coronary Computed Tomography Angiography Versus Standard Retrospective Spiral Acquisition in Patients With Atrial Fibrillation
Authors: Prazeres Carlos Eduardo Elias dos , Magalhães Tiago Augusto , de Castro Carneiro Adriano Camargo , Cury Roberto Caldeira , de Melo Moreira Valéria , Bello Juliana Hiromi Silva Matsumoto , Rochitte Carlos Eduardo 
Published: April 2017

Objective
The aim of this study was to compare image quality and radiation dose of coronary computed tomography (CT) angiography performed with dual-source CT scanner using 2 different protocols in patients with atrial fibrillation.

Methods
Forty-seven patients with AF underwent 2 different acquisition protocols: double high-pitch (DHP) spiral acquisition and retrospective spiral acquisition. The image quality was ranked according to a qualitative score by 2 experts: 1, no evident motion; 2, minimal motion not influencing coronary artery luminal evaluation; and 3, motion with impaired luminal evaluation. A third expert solved any disagreement.

Results
A total of 732 segments were evaluated. The DHP group (24 patients, 374 segments) showed more segments classified as score 1 than the retrospective spiral acquisition group (71.3% vs 37.4%). Image quality evaluation agreement was high between observers (κ = 0.8). There was significantly lower radiation exposure for the DHP group (3.65 [1.29] vs 23.57 [10.32] mSv).

Conclusions
In this original direct comparison, a DHP spiral protocol for coronary CT angiography acquisition in patients with atrial fibrillation resulted in lower radiation exposure and superior image quality compared with conventional spiral retrospective acquisition.
Salicylic acid perturbs sRNA-gibberellin regulatory network in immune response of potato toPotato virus Yinfection
Authors: Križnik Maja , Petek Marko , Dobnik David , Ramšak Živa , Baebler Špela , Pollmann Stephan , Kreuze Jan , Žel Jana , Gruden Kristina 
Published: April 2017

AbstractPotato virus Yis the most economically important potato viral pathogen. We aimed at unraveling the roles of small RNAs (sRNAs) in the complex immune signaling network controlling the establishment of tolerant response of potato cv. Désirée to the virus. We constructed a sRNA regulatory network connecting sRNAs and their targets to link sRNA level responses to physiological processes. We discovered an interesting novel sRNAs-gibberellin regulatory circuit being activated as early as 3 days post inoculation before viral multiplication can be detected. Increased levels of miR167 and phasiRNA931 were reflected in decreased levels of transcripts involved in gibberellin biosynthesis. Moreover, decreased concentration of gibberellin confirmed this regulation. The functional relation between lower activity of gibberellin signaling and reduced disease severity was previously confirmed in Arabidopsis-virus interaction using knockout mutants. We further showed that this regulation is salicylic acid-dependent as the response of sRNA network was attenuated in salicylic acid-depleted transgenic counterpart NahG-Désirée expressing severe disease symptoms. Besides downregulation of gibberellin signaling, regulation of several other parts of sRNA network in tolerant Désirée revealed similarities to responses observed in mutualistic symbiotic interactions. The intertwining of different regulatory networks revealed shows how developmental signaling, disease symptom development and stress signaling can be balanced.
Molecular mapping ofYrTZ2, a stripe rust resistance gene in wild emmer accession TZ-2 and its comparative analyses withAegilops tauschii
Authors: Wang Zhenzhong , Xie Jingzhong , Guo Li , Zhang Deyun , Li Genqiao , Fang Tilin , Chen Yongxing , Li Jun , Wu Qiuhong , Lu Ping , Wang Yong , Li Miaomiao , Wu Haibin , Zhang Yan , Yang Wuyun , Luo Ming-Cheng , Fahima Tzion , Liu Zhiyong 
Published: April 2017

ABSTRACTWheat stripe rust, caused byPuccinia striiformisf. sp.tritici(Pst), is a devastating disease that can cause severe yield losses. Identification and utilization of stripe rust resistance genes are essential for effective breeding against the disease. Wild emmer accession TZ-2, originally collected from Mount Hermon, Israel, confers near-immunity resistance against several prevailingPstraces in China. A set of 200 F6:7recombinant inbred lines (RILs) derived from a cross between susceptible durum wheat cultivar Langdon and TZ-2 was used for stripe rust evaluation. Genetic analysis indicated that the stripe rust resistance of TZ-2 toPstrace CYR34 was controlled by a single dominant gene, temporarily designatedYrTZ2. Through bulked segregant analysis (BSA) and SSR mapping,YrTZ2was located on chromosome arm 1BS and flanked by SSR markersXwmc230andXgwm413with genetic distance of 0.8 cM (distal) and 0.3 cM (proximal), respectively. By applying wheat 90K iSelect SNP genotyping assay, 11 polymorphic loci (consist of 250 SNP markers) closely linked withYrTZ2were identified.YrTZ2was further delimited into a 0.8 cM genetic interval between SNP markerIWB19368and SSR markerXgwm413, and co-segregated with SNP markerIWB28744(attached with 28 SNP markers). Comparative genomics analyses revealed high level of collinearity between theYrTZ2genomic region and the orthologous region ofAegilops tauschii1DS. The genomic region between lociIWB19368andIWB31649harboringYrTZ2is orthologous to a 24.5 Mb genomic region between AT1D0112 and AT1D0150, spanning 15 contigs on chromosome 1DS. The genetic and comparative maps ofYrTZ2provide framework for map-based cloning and marker-assisted selection (MAS) ofYrTZ2.
Epigenetic Reprogramming of Tissue-Specific Transcription Promotes Metastasis
Authors: Teng Shuaishuai , Li Yang , Yang Ming , Qi Rui , Huang Yiming , Wang Qianyu , Li Shasha , Lin Kequan , Cheng Yujing , Lu Zhi John , Wang Dong 
Published: April 2017

SUMMARYTumor metastasis is the cause of death for 90% of cancer patients, and no currently-available therapies target this multi-step process in which cancer cells spread from the local tissue of a primary tumor to distant organs where they establish secondary tumors1. Although epithelial-to-mesenchymal transition2, tumor-secreted exosomes3, epigenetic regulators as well as other genes4-8have been implicated in metastasis, little is known about how cells adapt to and colonize new tissue environments. Here, we show that the epigenetics-mediated reprogramming of tissue-specific gene transcription in cancer cells promotes metastasis. Using colorectal cancer (CRC) as a model, we found in both clinical and cell line studies that metastatic CRC cells lose their colon-specific gene transcription program and gain a liver-specific gene transcription program as they metastasize in the liver. Further, we found this transcription reprogramming is driven by a reshaped epigenetic landscape of both typical and super-enhancers. Chemical inhibition of enhancer activity disrupts the ability of cells to execute altered transcription programs and consequently inhibits metastasis. Binding motif analysis of the enhancers in liver metastatic CRC cells identified the liver-specific transcription factor FOXA2 as a key regulator, and knocking down ofFOXA2expression prevents the colonization of metastatic CRC cells in the liver of a mice xenograft model. These results, together with additional observations of similar reprogramming in several cohorts of clinical CRC tumor samples and in multiple other forms of metastatic cancers, indicate that this reprogramming may be a common feature of metastasis in multiple cancers and suggest the targeted disruption of this epigenetic reprogramming as a strategy for the development of therapies to treat metastasis, the leading cause of cancer-related mortality.
Genotype-by-Environment Interactions Affecting Heterosis in Maize
Authors: Li Zhi , Coffey Lisa , Garfin Jacob , Miller Nathan D. , White Michael R. , Spalding Edgar P. , Leon Natalia de , Kaeppler Shawn M. , Schnable Patrick S. , Springer Nathan M. , Hirsch Candice N. 
Published: April 2017

ABSTRACTThe environment can influence heterosis, the phenomena in which the offspring of two inbred parents exhibits phenotypic performance beyond the inbred parents for specific traits. In this study we measured 25 traits in a set of 47 maize hybrids and their inbred parents grown in 16 different environments, and each had varying levels of average productivity. By quantifying 25 vegetative and reproductive traits across the life cycle we were able to analyze interactions between the environment and multiple distinct instances of heterosis. The magnitude and rank among hybrids of better-parent heterosis (BPH) varied for the different traits and environments. Across the traits, a higher within plot variance was observed for inbred lines compared to hybrids. However, for most traits, variance across environments was not significantly different for inbred lines compared to hybrids. Further, for many traits the correlations of BPH to hybrid performance and BPH to better parent performance were of comparable magnitude. These results indicate that inbreds and hybrids are showing similar trends in environmental response and are both contribute to genotype-by-environment interactions for heterosis. This study highlights that degree of heterosis is not an inherent trait of a specific hybrid, but varies depending on the trait measured and the environment where that trait is measured. Studies that attempt to correlate molecular processes with heterosis are hindered by the fact that heterosis is not a consistent attribute of a specific hybrid.
Repurchase decision for music products in Taiwan: physical versus online media
Authors: Wu ChienHsing , Tao Yu-Hui , Lin Yu-Min 
Published: April 2017

Purpose
Consumer behaviors in internet are changing over time. The purpose of this paper is to propose and examine a research model that describes the repurchase behavior for the legal and paid music products of physical genre and online genre. The consumption value theory is used to develop the research model. Comparison of physical genre with online genre is presented. Implications and suggestions are addressed.

Design/methodology/approach
The research model is examined empirically. The research targeted music product consumers who had purchasing experience in the past one year. The research results are obtained, and the findings are revealed on the basis of 728 valid music product consumers.

Findings
The functional, emotional and epistemic value are the significant driving factors, though it shows a limited distinction for the two types. In comparing of the concepts of designed functional value, physical music consumers tend to have a stronger enthusiasm in music consumption. Social value and conditional value are not the predicators of repurchase satisfaction, implying that the music consumption is self-oriented for any normal amusement. The epistemic value shows significant on all levels of significance for the physical type, whereas insignificant if a = 0.01 for the type of online.

Originality/value
The research model is applied for the two contrariety product types, and to make a comparison, trying to understand the reasons why music fans are still willing to spend money on music products and what factors make them choose between product genres. After fluctuation and alternation of the music industry within this decade, this research provides a reference and correlated results for the future studies for the related studies, especially for the prosperous physical parallel imports items and online music.
Fast computation of accurate sphere-cube intersection volume
Authors: Jones Bruce D. , Williams John R. 
Published: April 2017

Purpose
Volume mapping of large spherical particles to a Cartesian grid with smaller grid elements is typically required in application of simple immersed boundary conditions in coupled engineering simulations. However, there exists no unique analytical solution to computation of the volume of intersection between spheres and cubes. The purpose of this paper is to determine a suitable solution to this problem depending on the required level of accuracy.

Design/methodology/approach
In this work, existing numerical techniques for computing intersection volume are reviewed and compared in terms of accuracy and performance. In addition to this, a more efficient linear relationship is proposed and included in this comparison.

Findings
The authors find in this work that a simple linear relationship is both acceptably accurate and more computationally efficient than the contemporary techniques.

Originality/value
This simple linear approach may be applied to accurately compute solutions to fluid-particle systems with very large numbers of particles.
Applications of the symplectic method in quasi-static analysis for viscoelastic functionally graded materials
Authors: Zhang W.X. , Liu R.G. , Bai Y. 
Published: April 2017

Purpose
For general quasi-static problems of viscoelastic functionally graded materials (VFGMs), the correspondence principle can be applied only for simple structures with a closed form solution of the corresponding elastic problem exists. In this paper, a new symplectic approach, according to the correspondence principle between linearly elastic and viscoelastic solids, is proposed for quasi-static VFGMs.

Design/methodology/approach
Firstly, by employing the method of separation of variables, all the fundamental eigenvectors of the governing equations are obtained analytically. Then, the satisfactions of boundary conditions prescribed on the ends and laterals are discussed based on the variable substitution and the eigenvector expansion methods.

Findings
In the numerical examples, some boundary condition problems are given. The results show the local effects due to the displacement constraints.

Originality/value
The paper provides an innovative technique for quasi-static problems of VFG Ms. Its correctness and the efficiency are well suported by numerical results.
Patch size setup and performance/cost trade-offs in multi-objective EM-driven antenna optimization using sequential domain patching
Authors: Koziel Slawomir , Bekasiewicz Adrian 
Published: April 2017

Purpose
This paper aims to assess control parameter setup and its effect on computational cost and performance of deterministic procedures for multi-objective design optimization of expensive simulation models of antenna structures.

Design/methodology/approach
A deterministic algorithm for cost-efficient multi-objective optimization of antenna structures has been assessed. The algorithm constructs a patch connecting extreme Pareto-optimal designs (obtained by means of separate single-objective optimization runs). Its performance (both cost- and quality-wise) depends on the dimensions of the so-called patch, an elementary region being relocated in the course of the optimization process. The cost/performance trade-offs are studied using two examples of ultra-wideband antenna structures and the optimization results are compared to draw conclusions concerning the algorithm robustness and determine the most advantageous control parameter setups.

Findings
The obtained results indicate that the investigated algorithm is very robust, i.e. its performance is weakly dependent on the control parameters setup. At the same time, it is found that the most suitable setups are those that ensure low computational cost, specifically non-uniform ones generated on the basis of sensitivity analysis.

Research limitations/implications
The study provides recommendations for control parameter setup of deterministic multi-objective optimization procedure for computationally efficient design of antenna structures. This is the first study of this kind for this particular design procedure, which confirms its robustness and determines the most suitable arrangement of the control parameters. Consequently, the presented results permit full automation of the surrogate-assisted multi-objective antenna optimization process while ensuring its lowest possible computational cost.

Originality/value
The work is the first comprehensive validation of the sequential domain patching algorithm under various scenarios of its control parameter setup. The considered design procedure along with the recommended parameter arrangement is a robust and computationally efficient tool for fully automated multi-objective optimization of expensive simulation models of contemporary antenna structures.
Application of computational fluid dynamics to predict hydrodynamic downpull on high head gates
Authors: Koken Mete , Aydin Ismail , Sahin Akis 
Published: April 2017

Purpose
High head gates are commonly used in hydropower plants for flow regulation and emergence closure. Hydrodynamic downpull can be a critical parameter in design of the lifting mechanism. The purpose of this paper is to show that a simplified two-dimensional (2D) computational fluid dynamics solution can be used in the prediction of the downpull force on the gate lip by comparison of computed results to experimentally measured data.

Design/methodology/approach
In this study, ANSYS FLUENT CFD software was used to obtain 2D numerical solution for the flow field around a generic gate model located in a power intake structure which was previously used in an experimental study. Description of the flow domain, computational grid resolution, requirements on setting appropriate boundary conditions and methodology in describing downpull coefficient are discussed. Total number of 245 simulations for variable gate lip geometry and gate openings were run. The downpull coefficient evaluated from the computed pressure field as function of gate opening and lip angle are compared with the experimental results.

Findings
The computed downpull coefficient agrees well with the previous experimental results, except one gate with small lip angle where a separation bubble forms along the lip, which is responsible from this deviation. It is observed that three-dimensional (3D) effects are confined to the large gate openings where downpull is minimum or even reversed.

Research limitations/implications
In large gate openings, three dimensionality of the flow around gate slots plays an important role and departure from 2D solutions become more pronounced. In that case, one might need to perform a 3D solution instead.

Practical implications
This paper presents a very fast and accurate way to predict downpull force on high head gates in the absence of experimental data.

Originality/value
An extensive amount of simulations are run within the scope of this study. It is shown that knowing its limitations, 2D numerical models can be used to calculate downpull for a wide range of gate openings without the need of expensive experimental models.
Pressure fluctuation characteristics in the sidewall gaps of a centrifugal dredging pump
Authors: Cao Lei , Xiao Yexiang , Wang Zhengwei , Luo Yongyao , Zhao Xiaoran 
Published: April 2017

Purpose
The purpose of this paper is to study the pressure fluctuation characteristics in the sidewall gaps of a centrifugal dredging pump in detail and discover the excitation sources.

Design/methodology/approach
An unsteady numerical simulation with shear–stress transport–scale-adaptive simulation (SAS-SST) model was conducted for a centrifugal pump considering the sidewall gaps. The numerical codes were validated by a model test carried out in China Water Resources Beifang Investigation, Design and Research Co., Ltd. Fast Fourier transform was used to obtain the frequency components of the pressure fluctuation.

Findings
Pressure fluctuation characteristics inside the pump were analyzed for a condition near the design point. In the sidewall gaps, the circumferential, radial and axial distribution of the pressure fluctuation amplitude follow different laws. The non-axisymmetrical distribution of pressure fluctuation in the sidewall gaps shows that the unsteady flow in the volute casing which has a non-axisymmetrical geometry imposes an evident effect on the flow field in the sidewall gaps and the interaction between the main flow and the clearance flow cannot be neglected. There are several frequency components appearing as the dominant frequencies at different locations in the sidewall gaps, but the relatively stronger pressure fluctuations are all dominated by the rotating frequency. It indicates that the rotating impeller, which originally makes the shrouds rotate, is the primarily excitation source of the pressure fluctuations in the sidewall gaps.

Originality/value
The pressure fluctuation characteristics in the sidewall gaps of centrifugal pumps were first comprehensively analyzed. Unsteady flows in the sidewall gaps should be considered during the design and operation of centrifugal pumps.