bluuebunny/crossref_metadata_2025_split huggingface dataset:
Promises of artistic research and its actuality. Artistic research in teatre
Authors: Balevičiūtė Ramunė 
Published: July 2017

The article analyzes the phenomena of the rise of artistic research in academic research culture,its reasons and premises. On a theoretical level, artistic research is treated as a new promising paradigm of research; however, the concept of artistic research is not homologous and steady. The lack of prominent art works that would be the outcome of artistic research is considered to be the biggest handicap for a perfect reputation of artistic research. The article discusses if the contribution of artistic research to contemporary research culture as well as its significance both to academic discourse and artistic practice is not overestimated. When searching for an answer to this question, the article analyzes the advantages of artistic research and the possibilities to create specific knowledge as well as the weaknesses and controversies. In the second part of the essay, the author focuses on artistic research in theatre, particularly in acting. Finally, she suggests an alternative model of research that would involve both artists and scholars.
Validation of the BASALT model for simulating off‐axis hydrothermal circulation in oceanic crust
Authors: Farahat Navah X. , Archer David , Abbot Dorian S. 
Published: July 2017

AbstractFluid recharge and discharge between the deep ocean and the porous upper layer of off‐axis oceanic crust tends to concentrate in small volumes of rock, such as seamounts and fractures, that are unimpeded by low‐permeability sediments. Basement structure, sediment burial, heat flow, and other regional characteristics of off‐axis hydrothermal systems appear to produce considerable diversity of circulation behaviors. Circulation of seawater and seawater‐derived fluids controls the extent of fluid‐rock interaction, resulting in significant geochemical impacts. However, the primary regional characteristics that control how seawater is distributed within upper oceanic crust are still poorly understood. In this paper we present the details of the two‐dimensional (2‐D) BASALT (Basement Activity Simulated At Low Temperatures) numerical model of heat and fluid transport in an off‐axis hydrothermal system. This model is designed to simulate a wide range of conditions in order to explore the dominant controls on circulation. We validate the BASALT model's ability to reproduce observations by configuring it to represent a thoroughly studied transect of the Juan de Fuca Ridge eastern flank. The results demonstrate that including series of narrow, ridge‐parallel fractures as subgrid features produces a realistic circulation scenario at the validation site. In future projects, a full reactive transport version of the validated BASALT model will be used to explore geochemical fluxes in a variety of off‐axis hydrothermal environments.
Structure‐based design of ferritin nanoparticle immunogens displaying antigenic loops of Neisseria gonorrhoeae
Authors: Wang Liqin , Xing Daniel , Le Van Adriana , Jerse Ann E. , Wang Shuishu 
Published: July 2017

Effective vaccines are urgently needed to combat gonorrhea, a common sexually transmitted bacterial infection, for which treatment options are diminishing due to rapid emergence of antibiotic resistance. We have used a rational approach to the development of gonorrhea vaccines, and genetically engineered nanoparticles to present antigenic peptides of Neisseria gonorrhoeae, the causative agent of gonorrhea. We hypothesized that the ferritin nanocage could be used as a platform to display an ordered array of N. gonorrhoeae antigenic peptides on its surface. MtrE, the outer membrane channel of the highly conserved gonococcal MtrCDE active efflux pump, is an attractive vaccine target due to its importance in protecting N. gonorrhoeae from host innate effectors and antibiotic resistance. Using computational approaches, we designed constructs that expressed chimeric proteins of the Helicobacter pylori ferritin and antigenic peptides that correspond to the two surface‐exposed loops of N. gonorrhoeae MtrE. The peptides were inserted at the N terminus or in a surface‐exposed ferritin loop between helices αA and αB. Crystal structures of the chimeric proteins revealed that the proteins assembled correctly into a 24‐mer nanocage structure. Although the inserted N. gonorrhoeae peptides were disordered, it was clear that they were displayed on the nanocage surface, but with multiple conformations. Our results confirmed that the ferritin nanoparticle is a robust platform to present antigenic peptides and therefore an ideal system for rational design of immunogens.
An Operando Mechanistic Evaluation of a Solar‐Rechargeable Sodium‐Ion Intercalation Battery
Authors: Lou Shi Nee , Sharma Neeraj , Goonetilleke Damian , Saputera Wibawa Hendra , Leoni Thomas M. , Brockbank Paul , Lim Sean , Wang Da‐Wei , Scott Jason , Amal Rose , Ng Yun Hau 
Published: July 2017

AbstractSolar‐intercalation batteries, which are able to both harvest and store solar energy within the electrodes, are a promising technology for the more efficient utilization of intermittent solar radiation. However, there is a lack of understanding on how the light‐induced intercalation reaction occurs within the electrode host lattice. Here, an in operando synchrotron X‐ray diffraction methodology is introduced, which allows for real‐time visualization of the structural evolution process within a solar‐intercalation battery host electrode lattice. Coupled with ex situ material characterization, direct correlations between the structural evolution of MoO3 and the photo‐electrochemical responses of the solar‐intercalation batteries are established for the first time. MoO3 is found to transform, via a two‐phase reaction mechanism, initially into a sodium bronze phase, Na0.33MoO3, followed by the formation of solid solutions, NaxMoO3 (0.33 < x < 1.1), on further photointercalation. Time‐resolved correlations with the measured voltages indicate that the two‐phase evolution reaction follows zeroth‐order kinetics. The insights achieved from this study can aid the development of more advanced photointercalation electrodes and solar batteries with greater performances.
Coherent Enantiomer‐Selective Population Enrichment Using Tailored Microwave Fields
Authors: Pérez Cristóbal , Steber Amanda L. , Domingos Sérgio R. , Krin Anna , Schmitz David , Schnell Melanie 
Published: July 2017

AbstractWe report the experimental demonstration of coherent enantiomer‐selective enrichment of chiral molecules by employing a novel microwave five‐pulse scheme. Our results show that enantiomers can be selectively transferred to a rotational level of choice by applying sequences of resonant microwave pulses in a phase‐ and polarization‐controlled manner. This is achieved by simultaneously exciting all three kinds of electric dipole‐allowed rotational transitions and monitoring the effect on a fourth rotational transition of choice. Using molecular beams, we apply our method to two chiral terpenes and obtain a 6 % enantiomeric enrichment, which is one order of magnitude larger than that recently reported in a buffer‐gas cell experiment. This approach establishes a robust scheme for controlled manipulation of enantiomers using tailored microwave fields and opens up new avenues for chiral purification and enrichment that can be used in a broad scope of analytical or spectroscopic applications.
Quantitative and Qualitative Analysis of Three Classes of Sulfur Compounds in Crude Oil
Authors: Vetere Alessandro , Pröfrock Daniel , Schrader Wolfgang 
Published: July 2017

AbstractOwing to the environmental hazards arising from sulfur‐containing combustion products, strong legal regulations exist to reduce the sulfur content of transportation fuels down to a few ppm. With the ongoing depletion of low‐sulfur crude oil reservoirs, increased technological efforts are needed for crude oil refining to meet these requirements. The desulfurization step is a critical part of the refining process but partly suffers from the recalcitrance of certain species to sulfur removal and the inability to quantitatively understand the behavior of individual compound classes during the process. We herein present a new and simple approach for the parallel quantification of three different classes of sulfur species present in crude oils by LC separation and on‐line detection and quantification by ICP‐MS/MS. This approach will help to estimate the amount of recalcitrant species and thus facilitate the optimization of desulfurization conditions during fuel production.
Auflagerbereiche wandartiger Träger
Authors: Haberland Marco , Morgen Karl 
Published: July 2017

AbstractDie kritischen Bereiche von wandartigen Trägern sind die Auflagerbereiche. Ihre Bemessung und konstruktive Durchbildung bedürfen einer besonderen Beachtung, insbesondere wenn in Grenzbereiche vorgestoßen wird. Das Standardwerk über Jahrzehnte, das DAfStb Heft 240, ist heutzutage nicht mehr in allen Belangen konsistent mit dem inzwischen gültigen Eurocode 2. Vollständig sind beide derzeit nicht. Diese Lücken füllend finden sich an unterschiedlichen Stellen veröffentlichte Hilfestellungen und Empfehlungen. Dieser Aufsatz stellt eine Zusammenfassung der nach Meinung der Verfasser wesentlichen Aspekte bzgl. der Auflagerbereiche dar. Ergänzt wird dies durch Überlegungen zur mittelbaren Lagerung. Die Auflagerknoten sind sowohl bei unmittelbarer Lagerung als auch bei mittelbarer Lagerung nachzuweisen. Kann im Falle einer mittelbaren Lagerung der primäre Auflagerknoten nachgewiesen werden, kann die Lastübertragungszone konstruktiv bewehrt werden. Kann dieser Nachweis nicht erbracht werden, empfiehlt es sich, die Lastübertragungszone für die mittelbare Lagerung explizit zu bemessen.
Overflow metabolism and growth cessation in Clostridium thermocellum DSM1313 during high cellulose loading fermentations
Authors: Thompson R. Adam , Trinh Cong T. 
Published: July 2017

ABSTRACTAs a model thermophilic bacterium for the production of second‐generation biofuels, the metabolism of Clostridium thermocellum has been widely studied. However, most studies have characterized C. thermocellum metabolism for growth at relatively low substrate concentrations. This outlook is not industrially relevant, however, as commercial viability requires substrate loadings of at least 100 g/L cellulosic materials. Recently, a wild‐type C. thermocellum DSM1313 was cultured on high cellulose loading batch fermentations and reported to produce a wide range of fermentative products not seen at lower substrate concentrations, opening the door for a more in‐depth analysis of how this organism will behave in industrially relevant conditions. In this work, we elucidated the interconnectedness of overflow metabolism and growth cessation in C. thermocellum during high cellulose loading batch fermentations (100 g/L). Metabolic flux and thermodynamic analyses suggested that hydrogen and formate accumulation perturbed the complex redox metabolism and limited conversion of pyruvate to acetyl‐CoA conversion, likely leading to overflow metabolism and growth cessation in C. thermocellum. Pyruvate formate lyase (PFL) acts as an important redox valve and its flux is inhibited by formate accumulation. Finally, we demonstrated that manipulation of fermentation conditions to alleviate hydrogen accumulation could dramatically alter the fate of pyruvate, providing valuable insight into process design for enhanced C. thermocellum production of chemicals and biofuels. Biotechnol. Bioeng. 2017;114: 2592–2604. © 2017 Wiley Periodicals, Inc.
Chemical Composition, Antioxidant Properties, α‐Glucosidase Inhibitory, and Antimicrobial Activity of Essential Oils from Acacia mollissima and Acacia cyclops Cultivated in Tunisia
Authors: Jelassi Amira , Hassine Manel , Besbes Hlila Malek , Ben Jannet Hichem 
Published: July 2017

The genus Acacia is quite large and can be found in the warm subarid and arid parts, but little is known about its chemistry, especially the volatile parts. The volatile oils from fresh flowers of A. mollissima and A. cyclops (growing in Tunisia) obtained by hydrodistillation were analyzed by GC then GC/MS. Eighteen (94.7% of the total oil composition) and 23 (97.4%) compounds were identified in these oils, respectively. (E,E)‐α‐Farnesene (51.5%) and (E)‐cinnamyl alcohol (10.7%) constituted the major compounds of the flower oil of A. mollissima, while nonadecane (29.6%) and caryophyllene oxide (15.9%) were the main constituents of the essential oil of A. cyclops. Antioxidant activity of the isolated oils was studied by varied assays, i.e., 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) and 2,2‐azinobis 3‐ethylbenzothiazoline‐6‐sulfonic acid (ABTS); the isolated oils showed lowest IC50 (4 – 39 μg/ml) indicating their high antioxidant activity. The α‐glucosidase inhibitor activity was also evaluated and Acacia oils were found to be able to strongly inhibit this enzyme with IC50 values (81 – 89 μg/ml) very close to that of acarbose which was used as positive control. Furthermore, they were tested against five Gram‐positive and Gram‐negative bacteria and one Candida species. Essential oil of A. mollissima was found to be more active than that of A. cyclops, especially against Pseudomonas aeruginosa (MIC = 0.31 mg/ml and MBC = 0.62 mg/ml).
T315I clone selection in a Ph+ all patient under low‐dose ponatinib maintenance
Authors: Noetzli Jasmine , Gavillet Mathilde , Masouridi‐Levrat Stavroula , Duchosal Michel , Spertini Olivier 
Published: July 2017

Key Clinical MessageWe report here the clinical course of a Ph+ ALL patient who was treated with ponatinib 15 mg/day, as maintenance therapy, and developed a BCR‐ABL T315I mutation leading to ALL relapse. This clonal evolution was reversed, without adverse effects, by increasing ponatinib to 45 mg/day. To our knowledge, we have been confronted with the first clinical case of a T315I clonal selection of ALL caused by subeffective therapeutic level of the drug. This single patient experience highlights the risk of T315I clone selection in Ph+ ALL treated with reduced dose ponatinib.
High Energy/Power Supercapacitor Performances of Intrinsically Ordered Ruthenium Oxide Prepared through Fast Hydrothermal Synthesis
Authors: Šekularac Gavrilo , Košević Milica , Dekanski Aleksandar , Djokić Veljko , Panjan Matjaž , Panić Vladimir 
Published: July 2017

AbstractA simple one‐step microwave‐assisted and temperature‐controlled hydrothermal synthesis was applied to prepare a nanocrystalline RuO2 dispersion from an aqueous solution of RuCl3 for supercapacitive applications. The obtained RuO2 dispersions were subjected to dynamic light scattering in order to analyze the particle size distribution, whereas morphology and structural properties of the solid phase were investigated by using AFM, SEM, EDX, TEM, and XRD techniques. Ellipsoidally shaped 100–500 nm‐sized compact grains, joined into highly ordered prismatic agglomerates, are observed. Two types of grains are observed: more regular ones consisting of spherical, amorphous particles of a few nanometers in size, and irregular ones made of partially crystalline 10–80 nm‐sized particles. Consequently, the most dominant structure is 250‐nm grains. The particles tend to join tightly across their crystalline domains, which appears responsible for the formation of prismatic shapes of several micrometers. This arraying causes high capacitive activity ‐ specific capacitances of up to 800 F g−1 are registered, which negligibly depend on the charging/discharging rate. The synthesized material is of highly accessible internal structure, and is an excellent candidate for both low‐ and high‐power applications.
Rodlike Tetracene Derivatives
Authors: Roth Michael , Ahles Marcus , Gawrisch Christian , Schwalm Thorsten , Schmechel Roland , Melzer Christian , von Seggern Heinz , Rehahn Matthias 
Published: July 2017

AbstractEfficient and versatile synthetic access to rodlike tetracene derivatives was developed by means of Diels–Alder cycloaddition, halogenation, halogen–metal exchange, and transition metal mediated coupling reactions. Herein, the synthesis and structural, electrical, and charge‐transport properties of three of the resulting materials, namely, 2‐(tetracen‐2‐yl)tetracene, 1,4‐bis(2‐tetracenyl)benzene, and 2,5‐bis(2‐tetracenyl)thiophene, are presented. Good crystallization behavior on SiO2substrates, narrowing of the bandgap by 0.2 eV, and a decrease of the ionization potential of more than 0.5 eV compared to tetracene were observed. Charge‐carrier field‐effect mobilities on the order of 10−1 cm2 V−1 s−1, on/off ratios of 105, and threshold voltagesVth<15 V were found in thin‐film organic field‐effect transistors prepared by standard high‐vacuum deposition techniques.
Mode coopétition dans un cluster culturel? Le cas du secteur circassien montréalais
Authors: Poisson‐de Haro Serge , Myard Alexandre 
Published: July 2017

AbstractWe explore the relevance of the « coopetition » concept within Montreal's circus sector and the Montréal Complètement Cirque festival in particular. Our analysis is based on the cluster phenomena found in coopetition studies, which is a strategy used by companies in the technology sector. We formulate propositions that suggest these collaborative practices allow reduce tensions related to the innovation and creative processes' intrinsic uncertainty and also moderate the effects of a firms' limited resources. These practices are also related to public policies aimed at ensuring the sector's sustainability, the existence of interpersonal relations, and the need for more visibility on the sector and its actors. Copyright © 2017 ASAC. Published by John Wiley & Sons, Ltd.
Long‐term changes in Japanese women's facial skin color
Authors: Kikuchi Kumiko , Katagiri Chika , Yoshikawa Hironobu , Mizokami Yoko , Yaguchi Hirohisa 
Published: July 2017

AbstractIt has been suggested that skin color changes not only with advancing age but also with the times. The purpose of this study was to investigate changes in Japanese women's facial skin color over 25 years, as well as the changes in skin pigmentation that affect skin color. First, skin color changes in terms of Munsell color values were investigated. A total of 3181 Japanese women residing in the greater Tokyo area were enrolled, and datasets were collected using spectrophotometers, designated as the 1991, 2001, 2005, and 2015 data. The mean Munsell hue, value, and chroma were calculated for each measurement year. Next, the concentrations of melanin and hemoglobin were calculated from spectral data, to investigate changes in skin pigmentations. Finally, Monte Carlo simulations were performed to verify that the suggested changes in skin pigmentations brought about skin color changes. As a result, skin color significantly changed toward high lightness, low saturation, and high yellowness from the 1991 data to the 2001 data. From the 2005 to 2015 data, the skin color distribution shifted toward lower saturation and increased redness. In addition, the concentration of hemoglobin decreased significantly from the 1991 data to the 2001 data, while the melanin concentration decreased significantly from the 2005 data to the 2015 data.
An efficient approach for outlier detection in big sensor data of health care
Authors: Saneja Bharti , Rani Rinkle 
Published: July 2017

SummaryIn recent years, wireless sensor networks are pervasive and are generating tons of data every second. Performing outlier detection to detect faulty sensors from such a large amount of data becomes a challenging task. Most of the existing techniques for outlier detection in wireless sensor networks concentrate only on contents of the data source without considering correlation among different data attributes. Moreover, these methods are not scalable to big data. To address these 2 limitations, this paper proposes an outlier detection approach based on correlation and dynamic SMO (sequential minimal optimization) regression that is scalable to big data. Initially, correlation is used to find out strongly correlated attributes and then the point anomalous nodes are detected using dynamic SMO regression. For fast processing of big data, Hadoop MapReduce framework is used. The experimental analysis demonstrates that the proposed approach efficiently detects the point and contextual anomalies and reduces the number of false alarms. For experiments, real data of sensors used in body sensor networks are taken from Physionet database.
Poorly differentiated vaginal adenocarcinoma with aggressive behavior—Pap smear findings
Authors: Eleutério José , de Freitas Francisca Margalene Medeiros , Oliveira Denise Nunes , Moreira David Freitas , Pessoa Mirley Sângela 
Published: July 2017

AbstractVaginal carcinoma is a rare condition. In this report, we describe a case of a poorly differentiated aggressive adenocarcinoma in a woman with a three month history of vaginal bleeding and a negative Pap smear done six months prior to her consultation. Specular examination showed a normal cervix, but there was a bleeding ulcer (2 cm in diameter) in the upper third of the vagina. Cytology revealed poorly differentiated atypical cells, and the biopsy established a diagnosis of vaginal adenocarcinoma with little differentiation. Within two months, the patient died without diagnosis of a primary tumor site other than the vagina.
River reaches with impaired riparian tree cover and channel morphology have reduced thermal resilience
Authors: O'Briain Rossa , Shephard Samuel , Coghlan Brian 
Published: July 2017

AbstractThis study evaluated the effects of riparian tree cover and channel morphology on the thermal regimes of 3 adjacent rivers in different years. Riparian tree cover was found to exert a strong modifying influence on stream temperature, with reduced mean maximum summer temperature at sites having greater tree cover. The effect of tree cover changed among years, such that greater cover was required to maintain a given water temperature regime in the warmer summer of 2013 than in 2014 or 2015. Water temperature was also related to mean depth in some years; shallower sites, typically associated with artificial channel widening, showed greater temperature extremes. These results suggest that the thermal resilience of modified streams can be improved by restoration of riparian tree cover and restored channel morphology. This finding is relevant to climate change proofing of temperate river channels, where cold‐water fauna are important elements of the biotic community.