bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biosorption of cationic dyes by Pará chestnut husk (Bertholletia excelsa)
Authors: Georgin Jordana , Marques Bianca Silva , Peres Enrique Chaves , Allasia Daniel , Dotto Guilherme Luiz 
Published: January 2018

Abstract
Pará chestnut husk (Bertholletia excelsa) (PCH), an agro-industrial waste largely generated in Brazil, was employed as a low-cost and efficient biosorbent to remove the cationic dyes Crystal Violet (CV) and Methylene Blue (MB) from aqueous media. PCH presented an amorphous structure containing carboxylic acids, esters, ketones and aldehydes on the surface. Non-porous and irregular particles were also observed. For both dyes, the biosorption capacity was favored under acid conditions. Equilibrium was attained within 40 min at 25 °C with a PCH dosage of 0.5 g L−1. The biosorption kinetic curves were satisfactory explained by the pseudo-first-order model. The Freundlich model was best for representing the equilibrium curves. The maximum biosorption capacities were 83.6 and 83.8 mg g−1 for CV and MB, respectively. PCH was efficient for treating a simulated textile effluent containing several dyes and chemicals, achieving a color removal of 90%. In this way, PCH can be considered as an option for treating colored effluents containing textile dyes.
Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart
Authors: Bartekova Monika , Barancik Miroslav , Ferenczyova Kristina , Dhalla Naranjan S. 
Published: January 2018

Background:
Ischemia-reperfusion (I/R) injury of the heart as a consequence of myocardial
infarction or cardiac surgery represents a serious clinical problem. One of the most prominent
mechanisms of I/R injury is the development of oxidative stress in the heart. In this regard,
I/R has been shown to enhance the production of reactive oxygen/nitrogen species in the heart
which lead to the imbalance between the pro-oxidants and antioxidant capacities of the endogenous
radical-scavenging systems.

Objectives:
Increasing the antioxidant capacity of the heart by the administration of exogenous antioxidants
is considered beneficial for the heart exposed to I/R. N-acetylcysteine (NAC) and Nmercaptopropionylglycine
(MPG) are two sulphur containing amino acid substances, which belong
to the broad category of exogenous antioxidants that have been tested for their protective potential
in cardiac I/R injury.

Observations:
Pretreatment of hearts with both NAC and MPG has demonstrated that these agents
attenuate the I/R-induced alterations in sarcolemma, sarcoplasmic reticulum, mitochondria and
myofibrils in addition to improving cardiac function. While experimental studies have revealed
promising data suggesting beneficial effects of NAC and MPG in cardiac I/R injury, the results of
clinical trials are not conclusive because both positive and no effects of these substances have been
reported on the post-ischemic recovery of heart following cardiac surgery or myocardial infarction.

Conclusion:
It is concluded that both NAC and MPG exert beneficial effects in preventing the I/Rinduced
injury; however, further studies are needed to establish their effectiveness in reversing the
I/R-induced abnormalities in the heart.
Design, Synthesis and Biological Evaluation of Uracil Derivatives as Novel VEGFR-2 Inhibitors
Authors: Liang Jingwei , Li Xinyang , Yang Su , He Xin , Wang Mingyang , Meng Fanhao 
Published: January 2018

Backgound: Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a crucial role in the
process of cancer angiogenesis. Type I inhibitors constitute the major ATP-competitive inhibitors and recognize
mainly the active conformation of VEGFR-2. Meanwhile, type II inhibitors recognize the inactive DFG (Asp-
Phe-Gly)-out conformation of VEGFR-2, which was a more promising approach for drug intervention.

Methods:
According to the lead compound of uracil skeleton, being screened out by structure-based virtual
screening, a series of uracil derivatives were designed and synthesized. Results: The inhibitory activities were
investigated against VEGFR-2 kinase in vitro. The results turned out that series A performed moderate inhibitory
activities, especially compound A4 exhibited the most potent inhibitory activity (IC50=0.029 µM).

Conclusion:
The lead compound was screened out by structure-based pharmacophore models, then two series
of uracil derivatives were synthesized according to it and evaluated for their inhibitory activities against
VEGFR-2. In this study, not only a potential inhibitor has been discovered, it also demonstrates the feasibility
of structure-based virtual screening method for drug discovery.
Ingresos en hospitalización a domicilio directamente desde el servicio de urgencias: una alternativa eficaz y segura
Authors: Dopico Santamariña Leticia María 
Published: January 2018

Objetivo: Analizar el perfil de pacientes con patología infecciosa que ingresan en HaD tras captación en Urgencias, soporte y calidad asistencial.Método: Estudio observacional retrospectivo. Variables: características del paciente, infección, tratamiento, parámetros de hospitalización e indicadores de calidad.Resultados: Incluidos 255 pacientes con edad media 71 años (48.63% varones; 51.37% mujeres) e índice medio de Charlson 4.91. Diagnósticos más frecuentes: infección urinaria (25.10%) y respiratoria (24.71%), sin identificación microbiológica en 62.75%. Aislamiento más frecuente: E.coli (21.32%) documentándose 10.20% bacteriemia y 14.51% criterios de sepsis. Todos necesitaron antibioterapia parenteral con media 6.5 días, siendo más empleados carbapenems (34.31%). Estancia media en Urgencias 21 horas y en HaD 7 días. Se registraron 9.41% de complicaciones obteniéndose tasa de reingreso 2.75%.Conclusiones: Tras estancia corta en Urgencias es posible el manejo eficaz de infecciones con criterios variables de gravedad y alta comorbilidad, dando el soporte necesario desde HaD, sin aumentar complicaciones ni reingresos.
National intellectual capital influence on economic growth in the European Union countries
Authors: Mačerinskienė Irena , Aleknavičiūtė Rasa 
Published: January 2018

Research background: Importance of intangible resources for country?s economic growth is widely recognized. However, empirical evidence of this influence is hard to show due to measurement limitations of intangible resources. Majority of empirical studies concentrates on the analysis of a specific type of intangible resource?s influence on economic growth. National intellectual capital concept provides background for an integrated assessment of the country's intangible resources. This new approach enables the estimation of intangible resources? influence to economic growth in a more complex way.
Purpose of the article: a) To examine various scientific approaches of the national intellectual capital and its impact on the economic growth; b) to offer a measurement model of the national intellectual capital influence on economic growth; c) to evaluate the specific European Union countries? intellectual capital?s effect on their economic growth.
Methods: Econometric analysis; refined factor value computation method using the stand-ardized regression coefficients; the SAW method; expert evaluation, cluster analysis; corre-lation and regression analyses.
Findings & Value added: A review of the economic growth theories showed that structural components of intellectual capital (human capital, structural capital, social capital, relational capital) in economic growth theories are analyzed as key determinants of economic growth. Our proposed research methodology consists time lag between variables and this let us evaluate casual relation. Empirical analysis of 25 European Union countries? intellectual capital?s effect on their economic growth rate revealed that national intellectual capital and the countries? level of economic development have statistically significant impact on economic growth rate. The analysis of intellectual capital components? influence on economic growth rate of 25 European Union countries showed that only human capital and the level of economic development have statistically significant influence. A more comprehensive human capital?s influence on economic growth analysis revealed that 63.1 percent of the long-term economic growth rate in 25 European Union countries can be explained by differences in their economic development level and differences in educational achievement factor values. Moreover, analysis of national intellectual capital effect on economic growth in separate clusters allowed to identify influence differences in each group of countries.
Economic growth and disparities: an empirical analysis for the Central and Eastern European countries
Authors: Kisiała Wojciech , Suszyńska Katarzyna 
Published: January 2018

Research background: The processes of economic convergence observed in many devel-oping countries are characterized by reduction of economic differences on the cross-country level, which are accompanied by growing internal economic inequalities. This may stem from the fact that in the catching-up countries a more dynamic growth pattern is observed in the economically strongest regions, which is initially reflected in spatial polarization and increasing regional inequalities. However, just as the countries reach higher levels of devel-opment, the diffusion of growth-inducing impulses to less-developed areas should lead to the spatial equalizing of the development levels and reducing regional inequalities.
Purpose of the article: The aim of the paper is to determine the relationship be-tween the level of economic growth and observed economic inequalities in Central and Eastern European (CEE) countries. The theoretical framework adopted to describe and explain those relations is the so-called Williamson?s hypothesis in which the relationship between the scale of regional inequalities and economic growth is illustrated by a curve shaped like an inverted U.
Methods: The research procedure was intended to verify William-son?s hypothesis by estimating parabolic econometric models. Indicators of economic growth along with measure of regional inequalities (Williamson?s coefficient of variation) were used in the regression modeling. The research period spanned the years 1995-2014.
Findings & Value added: In the light of the study of CEE countries, it was possible to observe both convergence symptoms as well as divergence tendencies. It can be thus stated that the analyzed CEE countries followed a similar path to the one observed earlier by Wil-liamson in other developing countries. However, the analyses conducted by the authors at the national and regional levels of CEE countries were equivocal and did not fully support the theoretical assumptions of Williamson?s hypothesis.
The impact of global risk on the performance of socially responsible and conventional stock indices
Authors: Śliwiński Paweł , Łobza Maciej 
Published: January 2018

Research background: In the last decades social responsible investment has evolved into an important and influential investment class. What supports then the development of SRI? The neoclassical approach suggests that the attractiveness of investment should result from the risk-return relationship that is satisfying for the investor. However, the performance analysis of SRI vs. conventional investment, conducted in numerous research papers, often delivers contradictory conclusions. If financial factors could not explain the phenomenon of SRI, nonfinancial factors may have played a decisive role in the formation of modern SRI market.
Purpose of the article: The purpose of this paper is to analyze financial investment perfor-mance of socially responsible vs. respective conventional indices in the periods of high, low and unidentified global risk. Therefore, a following research hypothesis was verified: SR indices perform financially better in high-risk periods than in low-risk periods. This hypoth-esis is justified by the assumption that, when selecting SRI, investors go by a longer invest-ment horizon than they do when selecting other investments, not subject to such verification.
Methods: Among SR indices, we chose three to compare them with their conventional counterparts: DJSI US vs. DJITR (USA), DJSI Korea vs. KOSPI (South Korea) and Respect Index vs. WIG20TR (Poland). The VIX index was used as the global measure of risk aver-sion. To measure the relative performance of SR and conventional indices in different risk periods, we applied risk-adjusted performance measures, including RSD, Sharpe and Treynor ratios, traditional and asymmetrical CAPM.
Findings & Value added: The research shows that conventional and socially responsible indices do not differ statistically in terms of risk and return irrespective of global risk. Our research confirms that the rising, socially responsible, investment market cannot be analyzed only through the prism of simplified rational choices. Additionally, it should be analyzed in terms of moral philosophy and behavioral economics, including the psycho-social features of investors.
Cultural, political and economic roots of the labor market institutional framework in the OECD and post-socialist countries
Authors: Pilc Michał 
Published: January 2018

Research background: The literature indicates that labor market institutions are determined by cultural, political and economic factors, but does not give explicit conclusions which of these vast group of factors dominates.
Purpose of the article: The goal of this study is to empirically assess whether cultural and political factors dominate over economic factors in shaping the labor market institutional framework in the OECD and post-socialist countries.
Methods: This framework can be measured by a vast group of indicators. We use 10 such variables that describe the group of 47 post-socialist and OECD countries (that did not experience economic transition) in the years 2005?2009. These indicators allow to construct one Employment Efficiency Index which explains almost 47% of the employment rate heterogeneity in the years 2010?2015. In the second step, the Employment Efficiency Index is regressed on 7 uncorrelated and standardized components that describe the cultural, political and economic characteristics of the analyzed countries in the years 1995?2004 and the Chow test is conducted in order to determine whether they influence the Index with the same strength in post-socialist and non-transition OECD countries.
Findings & Value added: The obtained results show that cultural and political factors have a stronger influence on labor market institutions. Moreover, the estimates reveal that the countries which experienced weak labor market performance in the period 1995?2004 did not make their institutional framework more pro-employment in the following years and, in consequence, also recorded low values of the employment rate in the period 2010?2015. Such result suggests that economic factors occurred to be on average an insufficient trigger for labor market reforms in the group of analyzed countries. Finally, the Chow test revealed that this conclusion is applicable to both post-socialist and non-transition OECD countries.
Expatriates and Home State Political Development
Authors: Brand Laurie A. 
Published: January 2018

Recent scholarship on diaspora-host state relations has increasingly examined the many dimensions of the involvement of communities abroad on the sending state. Much of this literature has focused on economic, political, and sociocultural remittances. This article shifts the focus to more structural elements as it seeks to read in various sending state institutions the very presence of a diaspora. Examples of institutional developments dating from independence to the present in government ministries, political parties, electoral and nationality laws, national boundaries, and sovereignty itself, are taken from the cases of Algeria, Egypt, Jordan, Lebanon, Morocco, and Tunisia. The analysis is intended to serve as a first step in establishing a new research program aimed at discerning the deeper structural impact of diasporas on state formation in the sending country.

Cover Image: The Mogamma Building in Cairo, May 2015.Image source, https://tinyurl.com/y9emz699.
EMPODERAMENTO DO PODER JUDICIÁRIO NAS QUESTÕES AFETAS A SEGURIDADE SOCIAL: INCREMENTALISMO OU INTERPRETAÇÃO CONSTITUCIONAL EVOLUTIVA EM MATÉRIA PREVIDENCIÁRIA
Authors: Lima Viviane Freitas Perdigão , Mendes Renata Caroline Pereira Reis 
Published: January 2018

O estudo parte do empoderamento do juiz nas inúmeras possibilidades interpretativas da Constituição, analisa política pública e precedentes do judiciário no direito à aposentadoria. O referencial teórico pauta-se em um Judiciário ao substituir políticas públicas do Poder Executivo e Legislativo (BAUM, 1987) na proteção dos riscos sociais o faz numa análise cautelosa da Constituição sem causar grandes rupturas (BARAK, 2002; ARAÚJO, 2017). Metodologicamente foca-se na dinâmica de proteção social, interpretação constitucional, Projeto Expedição da Cidadania, Resp n.º. 1.352.721-SP e Resp n.º 1649636/MT. Verifica-se postura judicial incrementando a constituição ao primar a solidariedade social.
NON MEDICAL FACTORS THAT AFFECT USAGE OF LONG ACTING REVERSIBLE CONTRACEPTIVE (LARC) IN WOMEN AFTER CHILDBIRTH IN INDONESIA
Authors: Paskaria Cindra 
Published: January 2018

The Long Acting Reversible Contraceptive ( LARC) is a method of contraception that is effective and efficient to prevent pregnancy or limit births, but its use in Indonesia is still low especially in women after childbirth. This may increase the risk of unwanted pregnancy and short birth interval. The purpose of this research is to find out what factors affect the use of LARC in women after childbirth in Indonesia. This research is an analysis of secondary data Indonesia Demographic and Health Survey 2012, with stamp 3,918 Women’s Reproductive Age, which is between 15-49 years old and they had given birth one year before the survey. The data were analyzed by using simple logistic regression analysis. This research shows that the proportion of women who used LARC after childbirth in Indonesia in 2012 was 7.31% and it was influenced by the level of socio-economic, domiciles, the husband’s level of education, the number of children born alive, the number of children still living, the desired number of children, the role of husband, and the role of religious figures. Keywords: LARC, women after childbirth, non medical factors
STUDY ON RUMPUT MUTIARA (Hedyotis Corimbosa) HERBS AS MEDICINE
Authors: Soemardji Andreanus A. , Anisa Ita N. , Damayanti Nareswari Alka 
Published: January 2018

“Rumput Mutiara” or Pearl grass (Hedyotis corymbosa) is one of medicinal plants used empirically by the Indonesian people to cure disease to maintain health. Many people have used pearl grass for a long time. This plant contains hentriacontane, stigmasterol, ursolic acid, oleanolicacid, β-sitosterol, sitisterol-D-glucoside, p-coumaric acid, flavonoid-glycosides, “baihua she she cao su” (possibility coumarin analog), iridoid glycosides, alizarin, korogenin, and bonding antragalol. Herbaceous plant is used and effetive as a relieve fever (antipyretic), anti-inflammatory, antibacterial, laxative urine(diuretic), removes heat and toxins (detoksikan), blood circulation, anti-cancer, the treatment of peptic ulcers, dysentery, exhausted maternity, and indigestion. This review article is a compilation of Hedyotis corymbosa herb as traditional medicinal plant and pharmacological researches of this herb that can be use as ethnopharmacological and pharmacological information of this medicinal herb. Keywords: Pearl grass, Hedyotis corymbosa, medicinal plants, ethnopharmacology, pharmacology.
The Preventive Effect of Fig Leaves’s (Ficus carica L.) towards Colon Histopathological Feature and IL-6 Serum Level on Ulcerative Colitis Induced Mice
Authors: Tiono Hartini 
Published: January 2018

Ulcerative colitis is a chronic inflammatory disease mainly affects sigmoid colon and rectum. The inflammation process will activate NF-κB and leads to proinflamatory cytokine release such as Interleukin-6 (IL-6). Fig leaves contain a high level of flavonoid which can prevent NF-κB activation, and further inhibits IL-6 secretion. This research aims to see the preventive effect of methanolic extract of fig leaves towards colon histopathological feature and IL-6 serum level on ulcerative colitis induced mice. Balb/C male mice were randomly assigned into 5 groups (n=5). The treatment groups were dextran suphate sodium (DSS) control group (group I), methanolic extract of Fig leaves dose 28 mg/ day control group (group II), and methanolic extract of Fig leaves dose 7 mg/ day (group III), 14 mg/ day (group IV), and 28 mg/ day (group V) for 14 days, which at the 8th till 14th day were given DSS to induce colitis. The results showed that both of colon mucosal damage and IL-6 serum level of group I were significantly different from other groups (p=0,029). In conclusion, the methanolic extract of Fig leaves can improve colon mucous damage and decrease IL-6 serum level on ulcerative colitis-induced mice. Keywords: ulcerative colitis, fig leaves, colon mucousal damage, interleukin-6
Peer Reviewers of JMH Volume 1 Number 4 August 2016
Authors: Team Editorial 
Published: January 2018

We would like to thank our peer reviewers for the precious contributions in providing clinical, scientific, and methodological expertise for JMH Volume 1 Number 4. We appreciate every thoughtful review of submitted manuscripts and for making important contributions to improve the scientific quality of articles published in JMH. We listed the names in alphabetical order. Dr.Achadiyani,dr.,M.KesProf. Andreanus A. Soemardji, DEAdr.Andri Rezano,M.Kes,PhDdr. Cindra Paskaria,MKMdr.Cherry Azaria, M.KesDr. dr Diana Krisanti Jasaputra, M.KesDr. Irda Fidriannydr.Jonathan,Sp.Raddr. Limdawati,Sp.PDdr. Lusiana Darsono, M.Kes.Dr. dr. Oeij Anindita Adhika, M.Kes., PA(K)Prof.Dr. Ridad Agoes,MPHdr.Sunny Wangko,M.Si,PA(K)dr. Sylvia Soeng, M.Kes., PA(K)Dr. Wahyu Widowati, M.Si.Prof. dr. Wahyuni Lukita Atmadja, PhD
Conceptos Clave en la Primera Teoría Crítica de la escuela de Frankfurt
Authors: Rojas Crotte Ignacio R. 
Published: January 2018

Este artículo pretende destacar los principales elementos conceptuales que integran una de las obras que, de hecho, inauguran la etápa mas célebre del Instituto de Investigaciones Sociales de Frankfurt en la década de los treinta; se trata de la Teoría Crítica de Max Horkheimer. Junto con ésta, y con la conducción de este autor en la Diracción del Organismo, inicia la asombrosa trayectoria de lo que hoy se conoce como escuela de Frankfurt.