bluuebunny/crossref_metadata_2025_split huggingface dataset:
The conundrum of social class: Disparities in publishing among STEM students in undergraduate research programs at a Hispanic majority institution
Authors: Grineski Sara , Daniels Heather , Collins Timothy , Morales Danielle X. , Frederick Angela , Garcia Marilyn 
Published: December 2017

AbstractResearch on the science, technology, engineering, and math (STEM) student development pipeline has largely ignored social class and instead examined inequalities based on gender and race. We investigate the role of social class in undergraduate student research publications. Data come from a sample of 213 undergraduate research participants majoring in STEM at a Hispanic‐majority institution. Based on generalized estimating equations that adjust for student demographics, research confidence, mentoring experiences, duration/number of research experiences, and clustering by major, we find that higher income students and continuing‐generation students (vs. first‐generation students) were significantly more likely to publish. Continuing‐generation students had an even greater likelihood of publishing than first‐generation students as students accrued more research confidence, spent more hours/week with faculty mentors, and conducted research for more months. Results suggest that undergraduate research programs designed to enhance diversity may help close some gaps (e.g., gender) but inadvertently reproduce class inequalities.
Superbase‐Added Choline Chloride‐Based Deep Eutectic Solvents for CO2 Capture and Sequestration
Authors: Bhawna  , Pandey Ashish , Pandey Siddharth 
Published: December 2017

AbstractDeep eutectic solvents (DESs) have emerged as inexpensive and environmentally‐benign liquid media for potential usage in chemical sciences. CO2 capture and sequestration by various substances is an active area of research in green chemistry. CO2 capture ability of DES‐based systems composed of salt choline chloride mixed with hydrogen bond donors urea (named reline), ethylene glycol (named ethaline), and monoethanolamine (named MEACC), are assessed in the absence and presence of three superbases: 1,5‐diazabicyclo[4.3.0]‐non‐5‐ene (DBN), 1,8‐diazabicyclo[5.4.0]undec‐7‐ene (DBU), and 1,5,7‐triazabicyclo[4.4.0]‐dec‐5‐ene (TBD), respectively. Addition of superbase is found to significantly increase the CO2 capture ability of the DESs reline and ethaline; for the DES MEACC, the CO2 capture ability is not changed much as monoethanolamine and MEACC on their own exhibit appreciable CO2 capture efficiency. It is found that the overall efficiency of CO2 capture is the best with superbase DBN as compared to DBU or TBD due to the lower steric hindrance around the imine structure. Presence of glycerol in the superbase‐added DESs results in decrease in CO2 capture ability due to significantly lower solubility of CO2 in glycerol. 13C NMR, FTIR and Raman spectroscopic measurements reveal that major part of the captured CO2 binds covalently to the electron‐rich functionalities present on the components of the DES with superbase assisting this association. The reversibility of the captured CO2 is assessed by introducing N2 gas into the CO2 captured superbase‐added DES system; it is found that only 21–25% CO2 by weight could be removed from the system through five cycles. Heating the CO2 captured superbase‐added DES system to 60 °C and 100 °C results in loss of only 23% and 35% CO2 by weight, respectively. Intramolecular excimer intensity of 1,10‐bis(1‐pyrenyl)decane and steady‐state fluorescence anisotropy of rhodamine 6G fluorescence probes effectively monitor the CO2 capture process as viscosity of the superbase‐added DES increases as more‐and‐more CO2 is captured. Efficiency, effectiveness, and robustness of superbase‐added DES‐based systems towards CO2 capture and sequestration is amply highlighted.
A Catalyst‐Free Cycloaddition Reaction: Access to Spiro[chroman‐3,2’‐indene‐1’,3’‐dione] Scaffolds
Authors: Han Yuzhe , Zhu Yingzu , Zhang Pangmiaomiao , Li Wenjun , Li Pengfei 
Published: December 2017

AbstractWe have reported herein a catalyst‐free cycloaddition of ortho‐hydroxyphenyl‐substituted para‐quinone methides and 2‐arylideneindane‐1,3‐diones by which a series of chromans featuring a spiro indane‐1,3‐dione scaffolds were obtained in high yields without any additives. Importantly, both anti‐ and syn‐ diastereomers could be obtained as single diastereomers respectively. Moverover, the current methold provides a novel and convenient approach for the efficient incorporation of the two biologically important scaffolds (chroman and spiro indane‐1,3‐dione).
Self‐Assembly of TbPc2 Single‐Molecule Magnets on Surface through Multiple Hydrogen Bonding
Authors: Pedrini Alessandro , Poggini Lorenzo , Tudisco Cristina , Torelli Martina , Giuffrida Antonino E. , Bertani Federico , Cimatti Irene , Otero Edwige , Ohresser Philippe , Sainctavit Philippe , Suman Michele , Condorelli Guglielmo G. , Mannini Matteo , Dalcanale Enrico 
Published: December 2017

AbstractThe complexation between 2‐ureido‐4[1H]‐pyrimidinone (UPy) and 2,7‐diamido‐1,8‐naphthyridine (NaPy) is used to promote the mild chemisorption of a UPy‐functionalized terbium(III) double decker system on a silicon surface. The adopted strategy allows the single‐molecule magnet behavior of the system to be maintained unaltered on the surface.
A Single‐Step Hydrothermal Route to 3D Hierarchical Cu2O/CuO/rGO Nanosheets as High‐Performance Anode of Lithium‐Ion Batteries
Authors: Wu Songhao , Fu Gaoliang , Lv Weiqiang , Wei Jiake , Chen Wenjin , Yi Huqiang , Gu Meng , Bai Xuedong , Zhu Liang , Tan Chao , Liang Yachun , Zhu Gaolong , He Jiarui , Wang Xinqiang , Zhang Kelvin H. L. , Xiong Jie , He Weidong 
Published: December 2017

AbstractAs anodes of Li‐ion batteries, copper oxides (CuO) have a high theoretical specific capacity (674 mA h g−1) but own poor cyclic stability owing to the large volume expansion and low conductivity in charges/discharges. Incorporating reduced graphene oxide (rGO) into CuO anodes with conventional methods fails to build robust interaction between rGO and CuO to efficiently improve the overall anode performance. Here, Cu2O/CuO/reduced graphene oxides (Cu2O/CuO/rGO) with a 3D hierarchical nanostructure are synthesized with a facile, single‐step hydrothermal method. The Cu2O/CuO/rGO anode exhibits remarkable cyclic and high‐rate performances, and particularly the anode with 25 wt% rGO owns the best performance among all samples, delivering a record capacity of 550 mA h g−1 at 0.5 C after 100 cycles. The pronounced performances are attributed to the highly efficient charge transfer in CuO nanosheets encapsulated in rGO network and the mitigated volume expansion of the anode owing to its robust 3D hierarchical nanostructure.
Boosting the Cycle Life of Aprotic Li–O2 Batteries via a Photo‐Assisted Hybrid Li2O2‐Scavenging Strategy
Authors: Qiao Yu , Liu Yang , Jiang Kezhu , Li Xiang , He Yibo , Li Qi , Wu Shichao , Zhou Haoshen 
Published: December 2017

AbstractThe development of the nonaqueous Li–O2 battery, a promising candidate for high‐gravimetric‐energy‐storage techniques, is seriously restrained by the high charge overpotential during electrochemical decomposition of insulating Li2O2. Benefiting from the photovoltage, photo‐assisted charging is revealed as a feasible method to reduce the charge potential. However, a long period of illumination will inevitably aggravate the degradation of the electrolyte. Herein, composed of contact‐ion‐pairs (CIPs), a newly introduced superconcentrated electrolyte presents superior stability against parasitic photocatalytic decomposition. More significantly, the conventional and photo‐assisted charging processes are rationally integrated as a unique hybrid strategy, in which the highly polarized charging stage is replaced by the photo‐assisted Li2O2‐scavenging process. By tuning the photocatalysis and Li2O2 electrochemical oxidization, the hybrid Li2O2‐scavenging strategy not only boosts the cycle life of rechargeable Li–O2 batteries but also opens possibilities in designing photocatalysis‐involved rechargeable energy‐storage battery systems.
Mapping the suitability for ice-core drilling of glaciers in the European Alps and the Asian High Mountains
Authors: GARZONIO ROBERTO , DI MAURO BIAGIO , STRIGARO DANIELE , ROSSINI MICOL , COLOMBO ROBERTO , DE AMICIS MATTIA , MAGGI VALTER 
Published: December 2017

ABSTRACTIce cores from mid-latitude mountain glaciers provide detailed information on past climate conditions and regional environmental changes, which is essential for placing current climate change into a longer term perspective. In this context, it is important to define guidelines and create dedicated maps to identify suitable areas for future ice-core drillings. In this study, the suitability for ice-core drilling (SICD) of a mountain glacier is defined as the possibility of extracting an ice core with preserved stratigraphy suitable for reconstructing past climate. Morphometric and climatic variables related to SICD are selected through literature review and characterization of previously drilled sites. A quantitative Weight of Evidence method is proposed to combine selected variables (i.e. slope, local relief, temperature and direct solar radiation) to map the potential drilling sites in mid-latitude mountain glaciers. The method was first developed in the European Alps and then applied to the Asian High Mountains. Model performances and limitations are discussed and first indications of new potential drilling sites in the Asian High Mountains are provided. Results presented here can facilitate the selection of future drilling sites especially on unexplored Asian mountain glaciers towards the understanding of climate and environmental changes.
Traditional ecological knowledge of the Critically Endangered Tooth-billed Pigeon Didunculus strigirostris, endemic to Samoa
Authors: SERRA GIANLUCA , SHERLEY GREG , FAILAGI S. AFELE , FOLIGA S. TALIE , UILI MOEUMU , ENOKA FIALELEI , SUAESI TEPA 
Published: December 2017

SummaryTraditional ecological knowledge (TEK) rigorously collected in four Key Biodiversity Areas (KBAs) of Samoa provided conservation and ecological insights about the endemic and evolutionarily distinctive Tooth-billed Pigeon Didunculus strigirostris. This study confirmed the 2006 estimate of a sharply declining population, supporting the recent conservation status assessment of Critically Endangered. Birds are killed as bycatch during hunting for the sympatric Pacific Pigeon Ducula pacifica, suggesting that this activity may be a key threat. The Tooth-billed Pigeon was observed by selected reliable indigenous hunters in several forest areas targeted in the present study, from a few months to several years ago. In the field, it was detected acoustically and identified through TEK and a mix of a TEK-scientific approach in four forest areas within three Samoan KBAs. Detection of the bird in the field is an issue due to its highly cryptic behaviour and because its call largely overlaps with one of the calls of Pacific Pigeon. Original TEK about the behavioural ecology of this species, including the fruiting trees mostly used and its terrestrial habits is reported. Short-term conservation recommendations are provided based on the findings.
High expression of MKP1/DUSP1 counteracts glioma stem cell activity and mediates HDAC inhibitor response
Authors: Arrizabalaga Olatz , Moreno-Cugnon Leire , Auzmendi-Iriarte Jaione , Aldaz Paula , Ibanez de Caceres Inmaculada , Garros-Regulez Laura , Moncho-Amor Veronica , Torres-Bayona Sergio , Pernía Olga , Pintado-Berninches Laura , Carrasco-Ramirez Patricia , Cortes-Sempere María , Rosas Rocío , Sanchez-Gomez Pilar , Ruiz Irune , Caren Helena , Pollard Steven , Garcia Idoia , Sacido Angel-Ayuso , Lovell-Badge Robin , Belda-Iniesta Cristobal , Sampron Nicolas , Perona Rosario , Matheu Ander 
Published: December 2017

AbstractThe elucidation of mechanisms involved in resistance to therapies is essential to improve the survival of patients with malignant gliomas. A major feature possessed by glioma cells that may aid their ability to survive therapy and reconstitute tumors is the capacity for self-renewal. We show here that glioma stem cells (GSCs) express low levels of MKP1, a dual-specificity phosphatase, which acts as a negative inhibitor of JNK, ERK1/2, and p38 MAPK, while induction of high levels of MKP1 expression are associated with differentiation of GSC. Notably, we find that high levels of MKP1 correlate with a subset of glioblastoma patients with better prognosis and overall increased survival. Gain of expression studies demonstrated that elevated MKP1 impairs self-renewal and induces differentiation of GSCs while reducing tumorigenesis in vivo. Moreover, we identified that MKP1 is epigenetically regulated and that it mediates the anti-tumor activity of histone deacetylase inhibitors (HDACIs) alone or in combination with temozolomide. In summary, this study identifies MKP1 as a key modulator of the interplay between GSC self-renewal and differentiation and provides evidence that the activation of MKP1, through epigenetic regulation, might be a novel therapeutic strategy to overcome therapy resistance in glioblastoma.
Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes
Authors: Son Young-Ok , Park Seulki , Kwak Ji-Sun , Won Yoonkyung , Choi Wan-Su , Rhee Jinseol , Chun Churl-Hong , Ryu Je-Hwang , Kim Don-Kyu , Choi Hueng-Sik , Chun Jang-Soo 
Published: December 2017

AbstractThe estrogen-related receptor (ERR) family of orphan nuclear receptor is composed of ERRα, ERRβ, and ERRγ, which are known to regulate various isoform-specific functions under normal and pathophysiological conditions. Here, we investigate the involvement of ERRs in the pathogenesis of osteoarthritis (OA) in mice. Among ERR family members, ERRγ is markedly upregulated in cartilage from human OA patients and various mouse models of OA. Adenovirus-mediated overexpression of ERRγ in mouse knee joint or transgenic expression of ERRγ in cartilage leads to OA. ERRγ overexpression in chondrocytes directly upregulates matrix metalloproteinase (MMP)-3 and MMP13, which are known to play crucial roles in cartilage destruction in OA. In contrast, genetic ablation of Esrrg or shRNA-mediated downregulation of Esrrg in joint tissues abrogates experimental OA in mice. Our results collectively indicate that ERRγ is a novel catabolic regulator of OA pathogenesis.
What is the temperature of a moving body?
Authors: Farías Cristian , Pinto Victor A. , Moya Pablo S. 
Published: December 2017

AbstractThe construction of a relativistic thermodynamics theory is still controversial after more than 110 years. To the date there is no agreement on which set of relativistic transformations of thermodynamic quantities is the correct one, or if the problem even has a solution. Starting from Planck and Einstein, several authors have proposed their own reasoning, concluding that a moving body could appear cooler, hotter or at the same temperature as measured by a local observer. In this article we present a review of the main theories of relativistic thermodynamics, with an special emphasis on the physical assumptions adopted by each one. We also present a set of relativistic transformations that we have derived by assuming the laws of Thermodynamics to be covariant. We found that under such assumptions a moving body appears to be hotter. Since relativistic thermodynamics is a topic that can be treated as part of an undergraduate course of classical thermodynamics or modern physics, the review and our own derivations presented here aim to encourage undergraduate physics students to open a discussion on the fundamental assumptions in thermodynamics and to engage in research activities early in their scientific career.
Connectome-harmonic decomposition of human brain activity reveals dynamical repertoire re-organization under LSD
Authors: Atasoy Selen , Roseman Leor , Kaelen Mendel , Kringelbach Morten L. , Deco Gustavo , Carhart-Harris Robin L. 
Published: December 2017

AbstractRecent studies have started to elucidate the effects of lysergic acid diethylamide (LSD) on the human brain but the underlying dynamics are not yet fully understood. Here we used ’connectome-harmonic decomposition’, a novel method to investigate the dynamical changes in brain states. We found that LSD alters the energy and the power of individual harmonic brain states in a frequency-selective manner. Remarkably, this leads to an expansion of the repertoire of active brain states, suggestive of a general re-organization of brain dynamics given the non-random increase in co-activation across frequencies. Interestingly, the frequency distribution of the active repertoire of brain states under LSD closely follows power-laws indicating a re-organization of the dynamics at the edge of criticality. Beyond the present findings, these methods open up for a better understanding of the complex brain dynamics in health and disease.
The proper use of coronary calcium score and coronary computed tomography angiography for screening asymptomatic patients with cardiovascular risk factors
Authors: Tay Shee Yen , Chang Po-Yen , Lao Wilson T. , Lin Ying Chin , Chung Yi-Han , Chan Wing P. 
Published: December 2017

AbstractEarly detection and treatment of coronary artery disease (CAD) can reduce incidences of acute myocardial infarction. In this study, we determined the proper use of contributing risk factors and coronary artery calcium score (CACS) when screening asymptomatic patients with coronary arterial stenoses using coronary computed tomography angiography (CCTA). We reviewed 934 consecutive patients who received CACS and CCTA between December 2013 and November 2016. At least one cardiovascular disease risk factor was present in each of the 509 asymptomatic participants. Patients were grouped based on CACS into “zero,” “minimal” (0 < CACS ≤ 10), “mild” (10 < CACS ≤ 100), “moderate” (100 < CACS ≤ 400), and “excessive” (CACS > 400). Males over 45 years old with diabetes mellitus and hypertension had a higher risk of significant coronary stenosis. In multivariate analysis, age, sex, hypertension, and diabetes mellitus remained significant predictors of stenosis. A CACS of zero occurred in 227 patients (44.6%). There were no significant differences between the “zero” and “minimal” groups (p = 0.421), but the “mild,” “moderate,” and “excessive” groups showed correlations with significant coronary stenosis. Age, sex, diabetes mellitus, and hypertension were associated with higher risk of significant coronary stenosis. Asymptomatic patients with CACSs of zero do not require CCTA, and thereby avoid unnecessary radiation exposure.
Cardiometabolic Risk Factors in Childhood, Adolescent and Young Adult Survivors of Acute Lymphoblastic Leukemia – A Petale Cohort
Authors: Levy Emile , Samoilenko Mariia , Morel Sophia , England Jade , Amre Devendra , Bertout Laurence , Drouin Simon , Laverdière Caroline , Krajinovic Maja , Sinnett Daniel , Lefebvre Geneviève , Marcil Valérie 
Published: December 2017

AbstractOur objectives were to assess the prevalence of cardiometabolic complications in children, adolescents, and young adult survivors of childhood acute lymphoblastic leukemia (cALL), to identify their predictors and the risk compared to the Canadian population. We performed a cardiometabolic assessment of cALL survivors from the PETALE cohort (n = 247, median age at visit of 21.7 years). In our group, overweight and obesity affected over 70% of women. Pre-hypertension and hypertension were mostly common in men, both adults (20%) and children (19%). Prediabetes was mainly present in women (6.1% of female adult survivors) and 41.3% had dyslipidemia. Cranial radiation therapy was a predictor of dyslipidemia (RR: 1.60, 95% CI: 1.07–2.41) and high LDL-cholesterol (RR: 4.78, 95% CI: 1.72–13.28). Male gender was a predictor for pre-hypertension and hypertension (RR: 5.12, 95% CI: 1.81–14.46). Obesity at the end of treatment was a predictor of obesity at interview (RR: 2.07, 95% CI: 1.37–3.14) and of metabolic syndrome (RR: 3.04, 95% CI: 1.14–8.09). Compared to the general population, cALL survivors were at higher risk of having the metabolic syndrome, dyslipidemia, pre-hypertension/hypertension and high LDL-cholesterol, while the risk for obesity was not different. Our results support the need for early screening and lifestyle intervention in this population.
Superoxide stability for reversible Na-O2 electrochemistry
Authors: Dilimon V. S. , Hwang Chihyun , Cho Yoon-Gyo , Yang Juchan , Lim Hee-Dae , Kang Kisuk , Kang Seok Ju , Song Hyun-Kon 
Published: December 2017

AbstractStabilizing superoxide (O2−) is one of the key issues of sodium-air batteries because the superoxide-based discharge product (NaO2) is more reversibly oxidized to oxygen when compared with peroxide (O22−) and oxide (O2−). Reversibly outstanding performances of sodium-oxygen batteries have been realized with the superoxide discharge product (NaO2) even if sodium peroxide (Na2O2) have been also known as the discharge products. Here we report that the Lewis basicity of anions of sodium salts as well as solvent molecules, both quantitatively represented by donor numbers (DNs), determines the superoxide stability and resultantly the reversibility of sodium-oxygen batteries. A DN map of superoxide stability was presented as a selection guide of salt/solvent pair. Based on sodium triflate (CF3SO3−)/dimethyl sulfoxide (DMSO) as a high-DN-pair electrolyte system, sodium ion oxygen batteries were constructed. Pre-sodiated antimony (Sb) was used as an anode during discharge instead of sodium metal because DMSO is reacted with the metal. The superoxide stability supported by the high DN anion/solvent pair ($${{\rm{CF}}}_{3}{{\rm{SO}}}_{3}$$

CF

3

SO

3

–/DMSO) allowed more reversible operation of the sodium ion oxygen batteries.
Increasing the permeability of Escherichia coli using MAC13243
Authors: Muheim Claudio , Götzke Hansjörg , Eriksson Anna U. , Lindberg Stina , Lauritsen Ida , Nørholm Morten H. H. , Daley Daniel O. 
Published: December 2017

AbstractThe outer membrane of gram-negative bacteria is a permeability barrier that prevents the efficient uptake of molecules with large scaffolds. As a consequence, a number of antibiotic classes are ineffective against gram-negative strains. Herein we carried out a high throughput screen for small molecules that make the outer membrane of Escherichia coli more permeable. We identified MAC13243, an inhibitor of the periplasmic chaperone LolA that traffics lipoproteins from the inner to the outer membrane. We observed that cells were (1) more permeable to the fluorescent probe 1-N-phenylnapthylamine, and (2) more susceptible to large-scaffold antibiotics when sub-inhibitory concentrations of MAC13243 were used. To exclude the possibility that the permeability was caused by an off-target effect, we genetically reconstructed the MAC13243-phenotype by depleting LolA levels using the CRISPRi system.