bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phenotypic heterogenecity of hematopoietic progenitor cells from placental tissue: comarative analysis with umbilical cord blood and fetal liver
Authors: Kuchma M. , Shablii V. , Kyryk V. , Onishchenko A. , Shablii Yu. , Lukash L. , Lobintseva G. 
Published: November 2016

The study of placental hematopoietic progenitor cells (HPCs) and comparison of their properties with other fetal and adult HPCs is necessary for assessing of their possible clinical application. It has been shown that HPCs from placenta are heterogeneous by phenotype: placental tissue contains three populations with different level of CD34 expression such as CD34+++CD45low/-, CD34++CD45low/- and CD34+/lowCD45low/-. Similar to fetal liver placenta contains both, population of CD34++CD45low/- and CD34+CD45low/-cells, suggesting hematopoiesis in placental tissue. CD34++CD45low/- population also expressed CD133, almost negative for lineage markers, and had lymphocyte-like morphology conforming the presence of primitive HPCs in this population. Additionally, we found later progenitors with phenotype CD34+/lowCD45+ in placental tissueas the majority of these cells expressed hematopoietic lineage markers. Population with phenotype CD34+++CD45low was observed in the placenta that may evidence for their generation in the placental tissue or migration from the other sites of hematopoiesis and changing phenotype under placental microenvironment.
Cryopreserved autologous multipotent mesenchymal stromal cells in the treatment of experimental tendopathy
Authors: Volkovа N. , Yukhta M. , Вlonskiy R. , Kostrub A. , Goltsev A. 
Published: November 2016

To date, stem cells application is one of the promising methods to treat pathologies of the musculoskeletal system.Material and methods. On the model of Achilles tendon degenerative injuries in rats (n = 60) we studied the effectiveness of local and systemic administration of cryopreserved autologous bone marrow multipotent mesenchymal stromal cells (MMSCs). We analyzed the morphology of the tissue, collagen type I content and the presence of labeled РКН-26 cells. Also the biomechanical study was performed on the 7th, 21st and 45th day after transplantation.Results. It was shown that MMSCs contribute to the activation of regenerative processes in damaged tendons that was manifested in the recovery of histological structure, strength and type I collagen content. Local method of cell administration resulted in more pronounced tendon recovery as compared to systemic method. Using РКН-26 we confirmed the presence of injected cells in damaged area within 21 days.Conclusion. The results of the study can be used for argumentation and development of methods for the treatment of degenerative and dystrophic tendon damages in clinical practice.
Synthetic method to investigate self-loosening of suspension fasteners considering nonlinear tire characteristics at the adhesion limit
Authors: Kaatz Marcus , Meywerk Martin , Spittler Sven 
Published: November 2016

AbstractA synthetic test method is described which is capable of investigating various suspension fasteners on a dynamic half-axle test rig. This test method is advantageous compared to an expensive and time-consuming driving cycle. In advance vehicle specific measured values that serve as input parameters for the test rig experiments are required. This study shows how the adhesion limit influences the interdependencies between vertical load, side slip angle and longitudinal slip. By means of multibody systems and in consideration of the determined nonlinear tire characteristics, this method can be applied to investigate suspension fasteners of vehicles without expensive and time-consuming test drives. Validation results of different vehicles are given which demonstrate that the method is appropriate to a wide range of vehicles.
Processing and characterization of graphene nano-platelet (GNP) reinforced aluminum matrix composites
Authors: Akçamlı Nazlı , Gökçe Hasan , Uzunsoy Deniz 
Published: November 2016

AbstractAluminum matrix composites containing graphene nano-platelets (GNPs) as reinforcement additive were fabricated by a two-step process consisting of mechanical alloying and pressureless sintering. The effects of graphene nano-platelets amounts and mechanical alloying duration on the microstructural and mechanical properties of aluminum were investigated. The characterization studies were performed by X-ray diffractometry, Raman spectroscopy, scanning electron microscopy/energy dispersive spectrometry, particle size analysis, differential scanning calorimetry, Archimedes' density and microhardness test method. The microhardness of composites increased gradually by the addition of 0.5 and 1 wt.-% GNP, whereas an adverse effect was observed by the increment of the GNP amount to 2 wt.-%.
Influence of welding parameters on the fracture of PE300 polyethylene friction stir spot welds
Authors: Çevik Bekir 
Published: November 2016

Abstract
In this study, polyethylene specimens were welded by using friction stir spot welding (FSSW) technique. Welding process was carried out by a rotation of 460 and 900 rpm. Under constant friction force, five different dwell times (20, 40, 60, 80 and 100 s), four different delay times (15, 30, 45 and 60 s) and three different pin profiles (M6 × 1, M6 × 1.25 and M6 × 1.5) were used. During the welding process, temperature measurements under the welding cenetrs were performed using a four multichannel K type digital thermometer. Tensile shear tests were used to characterize the samples. Tensile performance of the samples was significantly affected by the welding parameters.
Improving the visibility of phase gratings for Talbot-Lau X-ray imaging
Authors: Shashev Yury , Kupsch Andreas , Lange Axel , Müller Bernd R. , Bruno Giovanni 
Published: November 2016

Abstract
Talbot-Lau interferometry provides X-ray imaging techniques with significant enhancement of the radiographic contrast of weakly absorbing objects. The grating based technique allows separation of absorption, refraction and small angle scattering effects. The different efficiency of rectangular and triangular shaped phase gratings at varying detector distances is investigated. The interference patterns (Talbot carpets) are modeled for parallel monochromatic radiation and measured by synchrotron radiation. In comparison to rectangular shapes of phase gratings much higher visibility is obtained for triangular shapes which yield enhanced contrast of a glass capillary test specimen.
Vergleich von zerstörungsfreien und zerstörenden Prüfungen dünner Strukturklebungen in der Umformtechnik
Authors: Hofmann Dennis , Rahammer Markus , Liewald Mathias , Heckel Thomas , Huppmann Michael 
Published: November 2016

Kurzfassung
Der vorliegende Fachartikel stellt die wichtigsten zerstörungsfreien Prüfmethoden zur Qualitätssicherung von dünnen Strukturklebungen vor. Auf diese Weise wird ersichtlich, welche Methoden neben der zerstörenden Prüfung von dünnen Strukturklebungen eingesetzt werden können, um einen Haftfestigkeitsverlust zu detektieren. Steigende Leichtbau- und Dämpfungsanforderungen an großflächige Blechbauteile sorgen trotz erhöhter Kosten für einen zunehmenden Einsatz von modernen hybriden Schichtverbundwerkstoffen in zahlreichen Konstruktionsanwendungen. In der Luft- und Raumfahrtindustrie gehören solche Werkstoffe seit geraumer Zeit zum aktuellen Stand der Technik, wohingegen diese Werkstoffkonzepte in der mobilen Großserie derzeit nur selten zum Einsatz kommen. Neben dem Materialversagen der einzelnen Schichten von Schichtverbundwerkstoffen spielt das interlaminare Versagen der Schichten untereinander eine entscheidende Rolle. In der Umformtechnik ist es möglich, dass die polymere Zwischenschicht und das Deckblech nach der Umformung noch in Kontakt stehen, obwohl die Scherfestigkeit bereits überschritten wurde. Dieser Kraftschluss der beiden Fügepartner resultiert aus den schwachen Van-der-Waals-Kräften, die eine eindeutige Detektion mit Hilfe von zerstörungsfreier Prüfung erschweren. Die vorliegende Publikation soll die Eignung diverser zerstörungsfreier Prüfverfahren auf die Detektion von sogenannten „kissing bonds“ (schwaches Anhaften der Schichten nach Versagen der Verbindung) überprüfen.
Fracture behavior of an empty hole using the digital laser dynamic caustic method under directional controlled blasting
Authors: Guo Dongming , Liu Kang , Lu Hui , Yang Renshu , Wang Chunlai , Wang Yanbing 
Published: November 2016

Abstract
A systematic approach for using a new digital laser dynamic caustic (DLDC) method to provide useful insights for blasting crack propagation is illustrated. Under blast loading conditions, the dynamic behavior of blasting crack propagation and stress distribution around the empty hole between two boreholes were investigated. The results show that the crack tips were gradually deflected towards the empty hole. Then, it was eventually perforated under the guiding role of empty holes. By the interaction between the blast stress waves and the empty hole, the reflected tensile waves were generated. Moreover, these waves changed the stress field and reduced the velocity of the crack tip with a greater diameter for the empty hole. It was also found that the size of the empty holes had a slight influence on the direction of the principal stress. The larger the size of the empty hole was, the smaller was the speed of the crack propagation. In general, the crack propagation velocity of the circular empty hole was the highest, followed by that of the square hole and the notched circular hole. As the blast crack extended to the vicinity of the empty hole, the stress intensity factor of the crack tip started to show an upward trend again.
Effect of ZrSiO4 on the corrosion behavior of MgO-FeAl2O4 composite refractory materials
Authors: Bahtli Tuba , Aksel Cemail , Kavas Taner 
Published: November 2016

Abstract
In this study, the corrosion behavior of refractory materials that were produced by incorporating ZrSiO4 (zircon) at different ratios into MgO-FeAl2O4 (hercynite) were investigated. The values of density and open porosity of those samples were also measured, and the corrosion behaviors of those materials produced were examined. After performing corrosion tests, the corrosion resistance of composite refractory materials were determined by measuring the penetration distances and spreading areas. The incorporation of ZrSiO4 into MgO-FeAl2O4 generally decreased the porosity of composite refractory materials, and consequently reduced the penetration distances and spreading area values of the corroded regions of refractories as well. In addition, the formation of new phases and the microstructural changes which occurred were determined by XRD measurements and SEM analyses. On the basis of microstructural characterization carried out in the interface of clinker-refractory, the following observations had been determined: i) Ca2+ and Zr4+ elements forming CaZrO3 were located together in the same regions, ii) forsterite phase was formed due to the reaction between SiO2, which is released after dissociation of zircon as ZrO2 and SiO2 during sintering, and MgO, iii) the formation of new CaZrO3 and forsterite (Mg2SiO4) phases made a barrier effect against clinker, and iv) the amount of CaO decreased based on the EDX analysis made from clinker to refractory in a corroded region. The penetration of clinker to refractory showed a minimum level for the composition of MgO-5 wt.-% FeAl2O4-5 wt.-% ZrSiO4 and an improvement by about 38 % as compared to MgO-5 wt.-% FeAl2O4. This improvement is associated with a long service life of MgO-FeAl2O4-ZrSiO4 refractories for industrial applications.
Qualitätssicherung von Fahrzeug-rädern aus Leichtmetallguss
Authors: Grubisic Vatroslav 
Published: November 2016

Kurzfassung
Im vorliegenden Beitrag wird die Überprüfung der Dichtheit von Felgen gegossener Leichtmetallräder behandelt. Die Bedingungen für eine zuverlässige Dichtheitsprüfung und die Forderungen in den Spezifikationen und Werknormen einzelner Fahrzeughersteller werden erörtert. Die Ergebnisse der Erfassung von undichten Rädern im Betrieb in den Jahren 2011 bis 2015 eines Radherstellers wurden vorgestellt und bewertet. Abschließend wurde ein Vorschlag unterbreitet, die vorliegenden Normen einzelner Fahrzeughersteller an die Bedürfnisse der modernen, weitgehend automatisierten Dichtheitsprüfung anzupassen.
Dectin-1 Plays an Important Role in House Dust Mite–Induced Allergic Airway Inflammation through the Activation of CD11b+ Dendritic Cells
Authors: Ito Takashi , Hirose Koichi , Norimoto Ayako , Tamachi Tomohiro , Yokota Masaya , Saku Aiko , Takatori Hiroaki , Saijo Shinobu , Iwakura Yoichiro , Nakajima Hiroshi 
Published: November 2016

Abstract
It is well known that sensitization against fungi is closely associated with severity of asthma. Dectin-1 (gene symbol Clec7a), a C-type lectin receptor, recognizes the fungal cell wall component β-glucan, as well as some component(s) in house dust mite (HDM) extract. However, the roles of Dectin-1 in HDM-induced allergic airway inflammation remain unclear. In this study, we used Dectin-1–deficient (Clec7a−/−) mice to examine whether Dectin-1 is involved in HDM-induced allergic airway inflammation. We found that HDM-induced eosinophil and neutrophil recruitment into the airways was significantly attenuated in Clec7a−/− mice compared with that in wild-type mice. In addition, HDM-induced IL-5, IL-13, and IL-17 production from mediastinum lymph node cells was reduced in HDM-sensitized Clec7a−/− mice. Dectin-1 was expressed on CD11b+ dendritic cells (DCs), an essential DC subset for the development of allergic inflammation, but not on CD103+ DCs, plasmacytoid DCs, or lung epithelial cells. Transcriptome analysis revealed that the expression of chemokine/chemokine receptors, including CCR7, which is indispensable for DC migration to draining lymph nodes, was decreased in Clec7a−/− DCs. In accordance with these results, the number of HDM-labeled CD11b+ DCs in mediastinum lymph nodes was significantly reduced in Clec7a−/− mice compared with wild-type mice. Taken together, these results suggest that Dectin-1 expressed on CD11b+ DCs senses some molecule(s) in HDM extract and plays a critical role in the induction of HDM-induced allergic airway inflammation by inducing the expression of chemokine/chemokine receptors in DCs.
Mixed Finite Element Methods for Fourth Order Elliptic Optimal Control Problems
Authors: Manickam K. , Prakash P. 
Published: November 2016

AbstractIn this paper, a priori error estimates are derived for the mixed finite element discretization of optimal control problems governed by fourth order elliptic partial differential equations. The state and co-state are discretized by Raviart-Thomas mixed finite element spaces and the control variable is approximated by piecewise constant functions. The error estimates derived for the state variable as well as those for the control variable seem to be new. We illustrate with a numerical example to confirm our theoretical results.
A Multiple Interval Chebyshev-Gauss-Lobatto Collocation Method for Ordinary Differential Equations
Authors: Wang Zhong-Qing , Mu Jun 
Published: November 2016

AbstractWe introduce a multiple interval Chebyshev-Gauss-Lobatto spectral collocation method for the initial value problems of the nonlinear ordinary differential equations (ODES). This method is easy to implement and possesses the high order accuracy. In addition, it is very stable and suitable for long time calculations. We also obtain thehp-version bound on the numerical error of the multiple interval collocation method underH1-norm. Numerical experiments confirm the theoretical expectations.
Bivariate Polynomial Interpolation over Nonrectangular Meshes
Authors: Qian Jiang , Zheng Sujuan , Wang Fan , Fu Zhuojia 
Published: November 2016

AbstractIn this paper, bymeans of a new recursive algorithm of non-tensor-product-typed divided differences, bivariate polynomial interpolation schemes are constructed over nonrectangular meshes firstly, which is converted into the study of scattered data interpolation. And the schemes are different as the number of scattered data is odd and even, respectively. Secondly, the corresponding error estimation is worked out, and an equivalence is obtained between high-order non-tensor-product-typed divided differences and high-order partial derivatives in the case of odd and even interpolating nodes, respectively. Thirdly, several numerical examples illustrate the recursive algorithms valid for the non-tensor-product-typed interpolating polynomials, and disclose that these polynomials change as the order of the interpolating nodes, although the node collection is invariant. Finally, from the aspect of computational complexity, the operation count with the bivariate polynomials presented is smaller than that with radial basis functions.
Case Study - Alpha
Authors: Leybourne Stephen 
Published: November 2016

This case study was developed from an actual scenario by Dr. Steve Leybourne of Boston University. The case documents the historical evolution of an organization, and has been used successfully in courses dealing with organizational and cultural change, and the utilization of ‘soft skills’ in project-based management.This is a short case, ideal for classroom use and discussion. The issues are easily accessible to students, and there is a single wide ranging question that allows for the inclusion of many issues surrounding strategic decision-making, and behavioural and cultural change.Alpha was one of the earlier companies in the USA to invest in large, edge-of-town superstores, with plentiful free vehicle parking, selling food and related household products.Alpha was created in the 1950s as a subsidiary of a major publicly quoted retail group. It started business by opening a string of very large discount stores in converted industrial and warehouse premises in the south of the United States. In the early days shoppers were offered a limited range of very competitively priced products.When Alpha went public in 1981 it was the fourth largest food retailer in the US, selling an ever-widening range of food and non-food products. Its success continued to be based on high volume, low margins and good value for money, under the slogan of ‘Alpha Price.’
Adopting Results Based Management in the Non-Profit Sector: Trócaire’s Experience
Authors: McKernan Eoghan , Kennedy Karen , Aldred Allison 
Published: November 2016

The increasing emphasis on aid effectiveness, accountability and impact measurement in international development and humanitarian work has generated a requirement for high quality internal systems for the management of programmes. To help to address this requirement, Trócaire adopted Results Based Management in the 20 countries in which it works. This paper provides an overview of Trócaire’s RBM journey, including the process of embedding the new approach in the organisation, lessons learnt from this process, the subsequent benefits that are emerging at field programme level and the challenges going forward.
Age of the Mt. Ortles ice cores, the Tyrolean Iceman and glaciation of the highest summit of South Tyrol since the Northern Hemisphere Climatic Optimum
Authors: Gabrielli Paolo , Barbante Carlo , Bertagna Giuliano , Bertó Michele , Binder Daniel , Carton Alberto , Carturan Luca , Cazorzi Federico , Cozzi Giulio , Dalla Fontana Giancarlo , Davis Mary , De Blasi Fabrizio , Dinale Roberto , Dragà Gianfranco , Dreossi Giuliano , Festi Daniela , Frezzotti Massimo , Gabrieli Jacopo , Galos Stephan P. , Ginot Patrick , Heidenwolf Petra , Jenk Theo M. , Kehrwald Natalie , Kenny Donald , Magand Olivier , Mair Volkmar , Mikhalenko Vladimir , Lin Ping Nan , Oeggl Klaus , Piffer Gianni , Rinaldi Mirko , Schotterer Ulrich , Schwikowski Margit , Seppi Roberto , Spolaor Andrea , Stenni Barbara , Tonidandel David , Uglietti Chiara , Zagorodnov Victor , Zanoner Thomas , Zennaro Piero 
Published: November 2016

Abstract. In 2011 four ice cores were extracted from the summit of Alto dell'Ortles (3859 m), the highest glacier of South Tyrol in the Italian Alps. This drilling site is located only 37 km southwest from where the Tyrolean Iceman,  ∼ 5.3 kyrs old, was discovered emerging from the ablating ice field of Tisenjoch (3210 m, near the Italian–Austrian border) in 1991. The excellent preservation of this mummy suggested that the Tyrolean Iceman was continuously embedded in prehistoric ice and that additional ancient ice was likely preserved elsewhere in South Tyrol. Dating of the ice cores from Alto dell'Ortles based on 210Pb, tritium, beta activity and 14C determinations, combined with an empirical model (COPRA), provides evidence for a chronologically ordered ice stratigraphy from the modern glacier surface down to the bottom ice layers with an age of  ∼ 7 kyrs, which confirms the hypothesis. Our results indicate that the drilling site has continuously been glaciated on frozen bedrock since  ∼ 7 kyrs BP. Absence of older ice on the highest glacier of South Tyrol is consistent with the removal of basal ice from bedrock during the Northern Hemisphere Climatic Optimum (6–9 kyrs BP), the warmest interval in the European Alps during the Holocene. Borehole inclinometric measurements of the current glacier flow combined with surface ground penetration radar (GPR) measurements indicate that, due to the sustained atmospheric warming since the 1980s, an acceleration of the glacier Alto dell'Ortles flow has just recently begun. Given the stratigraphic–chronological continuity of the Mt. Ortles cores over millennia, it can be argued that this behaviour has been unprecedented at this location since the Northern Hemisphere Climatic Optimum.
Transient Brugada phenocopy during evolving ischemic right bundle branch block
Authors: Ferrando-Castagnetto Federico , Rivara Alvaro , Vignolo Gustavo , Ricca-Mallada Roberto , Baranchuk Adrián 
Published: November 2016

A “Brugada phenocopy” (BrP) is a clinical presentation exhibiting the same electrocardiographic characteristics of true Brugada syndrome (BrS) in different clinical scenarios. We report the clinical case of a 59-year-old male patient with acute chest pain depicting BrP followed by extensive convex ST-segment elevation due to proximal thrombosis of the left descending coronary artery. Following successful percutaneous intervention and drug-eluting stent implantation, a classical right bundle branch block pattern emerged. We discussed possible mechanism and clinical implications of this unusual electrical sequence during acute myocardial injury.
Desempleo y política de “ingresos adecuados” en España e Italia
Authors: Martín Artiles Antonio , Molina Romo Oscar , Godino Pons Alejandro 
Published: November 2016

Las políticas de austeridad han reducido significativamente los márgenes de negociación de la política social en el contexto del diálogo social tripartito. De esta manera, los gobiernos de España e Italia han seguido una política de transferencia del riesgo hacia el ámbito territorial y local. Es precisamente en estos ámbitos donde se implementan las políticas de ingresos dirigidas a amortiguar situaciones de pobreza severa. Como resultado de esto, en la actualidad el sistema de ingresos mínimos está desarticulado y fragmentado, caracterizado por una escasa coordinación vertical (entre los diferentes niveles de gobierno) y horizontal (entre los actores), tanto en España como Italia. En cualquier caso, se observa como el discurso de la “inclusión activa” se ha extendido en los dos países, aunque con diferente énfasis. La política de ingresos mediante subsidios y ayudas ha estado ligada a la condicionalidad de la activación de los desempleados. El principio de condicionalidad es una tendencia vinculada a la exigencia de formación, disponibilidad y de aceptación de cualquier oferta de trabajo. La devaluación competitiva de los salarios y la condicionalidad son dos poderosos instrumentos de disciplina social orientada hacia la reducción del coste laboral y de la protección social.