bluuebunny/crossref_metadata_2025_split huggingface dataset:
Promoting knowledge sharing in academic environments using non-monetary factors
Authors: Dezdar Shahin 
Published: October 2017

Purpose
Knowledge sharing is very important in non-profit organizations such as academic institutes and universities. This research is a laudable attempt in this vital area to collaborate, refine and advance knowledge production endeavours in universities. The purpose of this study is to formulate a theoretical framework to investigate the non-monetary factors that encourage knowledge-sharing behaviour among postgraduate students.

Design/methodology/approach
A field survey was conducted among postgraduate students in Iranian public universities to obtain empirical evidence. Structural equation modelling was used to analyse the collected data.

Findings
The results revealed that knowledge-sharing behaviour is influenced by humility, interpersonal trust, reputation, self-efficacy and enjoyment of helping others.

Originality/value
Most of the prior studies focussed on rewards and monetary incentive factors to encourage knowledge sharing, whereas this paper examines the non-monetary factors that increase the willingness to share knowledge.
Truth and reconciliation in psychiatry: a response to Spandler and McKeown
Authors: Cresswell Mark 
Published: October 2017

PurposeThe purpose of this paper is to critique Spandler and McKeown’s recent advocacy of a truth and reconciliation (T&R) process in psychiatry.Design/methodology/approachA critique of a recent paper inMental Health Review Journal.FindingsThat Spandler and McKeown’s advocacy of a T&R process in psychiatry can be criticised from a number of inter-related practical, political and ethical perspectives.Originality/valueThe present critique contributes to the ongoing debate about the desirability of a T&R process in psychiatry.
Effectiveness of resilience capabilities in mitigating disruptions: leveraging on supply chain structural complexity
Authors: Birkie Seyoum Eshetu , Trucco Paolo , Fernandez Campos Pablo 
Published: October 2017

PurposeThis study aims to investigate the influence of supply chain (SC) complexity on the effectiveness of resilience capabilities in mitigating SC disruptions. Hypotheses about direct and moderating influences of complexity on resilience capabilities and performance change after disruption are built and quantitatively tested.Design/methodology/approachPartial least square-based structural equation modelling with formative constructs was used as an overall approach. Secondary data on SC disruptions, related performance change and resilience practices were collected from multiple sources through a predefined procedure. The collected data were systematically encoded prior to performing statistical analysis.FindingsSC structural complexity is found to have a significant positive relation with performance improvement after disruption, along with resilience capability; it also positively moderates the resilience–performance link.Research limitations/implicationsThe SC complexity factors the authors considered in this study do not include dynamic forms because of the nature of data collected. Future research may attempt to include and test whether the results of this study also hold when additional complexity parameters are taken into account.Practical implicationsManagers are often trying to reduce SC complexity. This study implies that some level of complexity is beneficial also for a better recovery of operational performance affected because of disruption. Resilience capabilities become more effective when leveraged on complexity in the SC.Originality/valueThis is the first study to empirically investigate the influence of SC complexity on the resilience–performance link.
Ideological battles in and out 1911
Authors: Cheung Siu Keung 
Published: October 2017

Purpose
During the centennial anniversary of Xinhai Revolution in 2011, the Chinese People’s Political Consultative Conference and the State Administration of Radio, Film, and Television supported the production of 1911 for celebrating such an important event that lead to the rise of the Republic of China in the contemporary Chinese history. This paper aims to reflect upon this film in relation to China’s propagation of “Greater China” for the Empire-building project.

Design/methodology/approach
By scrutinizing the film text and following the strait controversies over the film, this paper demonstrates how the Chinese Communist agents employed the coproduction model with Hong Kong for globalizing a cinematic discourse of Greater China in part of their Empire-building project.

Findings
The study challenges how contemporary Chinese history is ideologically and politically manipulated for advancing the Chinese Communist propaganda over Taiwan. The overall objective is to reflect upon the longstanding historical divergences that stand on the current geopolitical envision and strategy of China for reunification.

Originality/value
This paper provides an interdisciplinary reflection upon the intricate post-Cold War politics in part of the contemporary Chinese cinema under the China–Hong Kong coproduction model. The findings advance novel and timely insights into China’s current envision and strategy for reunification.
The colony writes back: nationalism and collaborative coloniality in the Ip Man series
Authors: Cheung Siu Keung , Law Wing Sang 
Published: October 2017

PurposeThe majority of Hong Kong filmmakers have pursued co-production with China filmmakers for having the Mainland market at the expense of local styles and sensitivities. To many critics, the two-part series of Ip Man and Ip Man II provide a paradigmatic case of film co-production that sell the tricks of Chinese kung fu, regurgitating the overblown Chinese nationalism against Japanese and kwai-lo. The purpose of this study is to rectify such observation of the Ip Man series.Design/methodology/approachThe authors read the series deconstructively as a postcolonial text in which Hong Kong identity is inscribed in the negotiated space in between different versions of Chinese nationalism.FindingsThe analysis points to the varying subversive features in the series from which Hong Kong’s colonial experiences are tacitly displayed, endorsed and rewritten into the Chinese nationalistic discourse whose dominance is questioned, if not debased.Originality/valueThis paper advances new research insights into the postcolonial reinvention of kung fu film and, by implication, the Hong Kong cinema in general.
Lost in Hong Kong
Authors: Lok Peter 
Published: October 2017

Purpose
The purpose of this paper is to explore how a neo-liberal nationalist discourse of China imagines the spatial identity of the post-1997 Hong Kong with reference to Lost in Hong Kong, a new Chinese middle-class film in 2015 with successful box office sales.

Design/methodology/approach
Textual analysis with the aid of psychoanalysis, postcolonial studies and semiotics is used to interpret the meaning of the film in this study. The study also utilizes the previous literature reviews about the formation of the Chinese national identity to help analyze the distinct identity of the Chinese middle class today.

Findings
The discussion pinpoints how the new Chinese middle class as neo-liberal nationalists take Hong Kong as a “bizarre national redemptive space”. While Hong Kong is cinematically constructed as such a national other, this paper argues that the Hong Kong in question stands not for itself but in a form of “reverse hallucination” for pacifying the new Chinese middle class’ trauma under the rapid neo-liberalization of China in the 1990s.

Originality/value
This paper shows the new of formation of the Chinese nationalist’s discourse, especially the new Chinese middle-class discourse on Hong Kong after 1997.
Multiple Hfq‐Crc target sites are required to impose catabolite repression on (methyl)phenol metabolism in Pseudomonas putida CF600
Authors: Wirebrand Lisa , Madhushani Anjana W. K. , Irie Yasuhiko , Shingler Victoria 
Published: October 2017

SummaryThe dmp‐system encoded on the IncP‐2 pVI150 plasmid of Pseudomonas putida CF600 confers the ability to assimilate (methyl)phenols. Regulation of the dmp‐genes is subject to sophisticated control, which includes global regulatory input to subvert expression of the pathway in the presence of preferred carbon sources. Previously we have shown that in P. putida, translational inhibition exerted by the carbon repression control protein Crc operates hand‐in‐hand with the RNA chaperon protein Hfq to reduce translation of the DmpR regulator of the Dmp‐pathway. Here, we show that Crc and Hfq co‐target four additional sites to form riboprotein complexes within the proximity of the translational initiation sites of genes encoding the first two steps of the Dmp‐pathway to mediate two‐layered control in the face of selection of preferred substrates. Furthermore, we present evidence that Crc plays a hitherto unsuspected role in maintaining the pVI150 plasmid within a bacterial population, which has implications for (methyl)phenol degradation and a wide variety of other physiological processes encoded by the IncP‐2 group of Pseudomonas‐specific mega‐plasmids.
Glycosylate and move! The glycosyltransferase Maf is involved in bacterial flagella formation
Authors: Sulzenbacher Gerlind , Roig‐Zamboni Véronique , Lebrun Régine , Guérardel Yann , Murat Dorothée , Mansuelle Pascal , Yamakawa Nao , Qian Xin‐Xin , Vincentelli Renaud , Bourne Yves , Wu Long‐Fei , Alberto François 
Published: October 2017

SummaryThe flagella of various Gram‐negative bacteria are decorated with diverse glycan structures, amongst them nonulosonic acids related to the sialic acid family. Although nonulosonic sugar biosynthesis pathways have been dissected in various pathogens, the enzymes transferring the sugars onto flagellin are still poorly characterized. The deletion of genes coding for motility associated factors (Mafs) found in many pathogenic strains systematically gives rise to nonflagellated bacteria lacking specific nonulosonic sugars on the flagellins, therefore, relating Maf function to flagellin glycosylation and bacterial motility. We investigated the role of Maf from our model organism, Magnetospirillum magneticum AMB‐1, in the glycosylation and formation of the flagellum. Deletion of the gene amb0685 coding for Maf produced a nonflagellated bacterium where the flagellin was still produced but no longer glycosylated. Our X‐ray structure analysis revealed that the central domain of Maf exhibits similarity to sialyltransferases from Campylobacter jejuni. Glycan analysis suggested that the nonulosonic carbohydrate structure transferred is pseudaminic acid or a very close derivative. This work describes the importance of glycosylation in the formation of the bacterial flagellum and provides the first structural model for a member of a new bacterial glycosyltransferase family involved in nonulosonic acids transfer onto flagellins.
The effects of single‐ and multiple‐dose administration of bococizumab (RN316/PF‐04950615), a humanized IgG2Δa monoclonal antibody binding proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects treated with and without atorvastatin: Results from four phase I studies
Authors: Gumbiner Barry , Joh Tenshang , Liang Hong , Wan Hong , Levisetti Matteo , Vana Alicia M. , Shelton David L. , Forgues Philippe , Billotte Stephan , Pons Jaume , Baum Charles M. , Garzone Pamela D. 
Published: October 2017

SummaryAimsThree single‐dose and one multiple‐dose phase I studies were conducted in subjects with primary hypercholesterolemia to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of bococizumab, a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor.MethodsThe dosing schedules for hypercholesterolemic subjects randomized in the four phase I studies were (1) ascending, single, intravenous (IV) bococizumab (0.3, 1, 3, 6, 12, or 18 mg/kg), or placebo (N = 48; baseline low‐density lipoprotein cholesterol [LDL‐C] ≥130 mg/dL); (2) single, IV bococizumab (0.5 or 4 mg/kg; no placebo) added to ongoing atorvastatin 40 mg/day (N = 24); (3) single, fixed, subcutaneous (SC) bococizumab (100 or 200 mg), or IV bococizumab (200 mg; no placebo; N = 49; baseline LDL‐C ≥130 mg/dL); and (4) weekly IV bococizumab (0.25, 0.5, 1, or 1.5 mg/kg) or placebo for 4 weeks (N = 67; baseline LDL‐C ≥130 mg/dL).ResultsBococizumab pharmacokinetics were well characterized following single IV or SC doses and following multiple IV doses. Exposure to single‐dose bococizumab increased slightly greater than dose‐proportionally and clearance decreased with increasing dose. In the single‐dose studies, maximal mean percent reductions from baseline in LDL‐C ranged from 43% (0.3 mg/kg) to 84% (18 mg/kg) in bococizumab‐treated subjects, compared with 2% for placebo. For the multiple‐dose study, maximal reductions in LDL‐C ranged from 55% (0.25 mg/kg) to 66% (1 mg/kg) in bococizumab‐treated subjects, compared with 9% for placebo. In all studies, adverse events were infrequent, transient, and not dose‐related.ConclusionsBococizumab was generally safe and well tolerated. Bococizumab lowered LDL‐C levels substantially in all four studies.
Urine angiostatin and VCAM‐1 surpass conventional metrics in predicting elevated renal pathology activity indices in lupus nephritis
Authors: Soliman Samar , Mohamed Fatma A. , Ismail Faten M. , Stanley Samantha , Saxena Ramesh , Mohan Chandra 
Published: October 2017

AbstractAimThe goal of this study is to investigate how urinary angiostatin, vascular cell adhesion molecule 1 (VCAM‐1) and established measures of renal function relate to specific histologic findings in paired kidney biopsy samples from patients with lupus nephritis (LN).MethodUrine samples were collected from 54 LN patients together with paired kidney biopsy samples and examined for urinary angiostatin and VCAM‐1 protein levels. Nonparametric tests were used to examine the association of both urinary biomarkers and established traditional laboratory markers of renal function with nine specific renal histologic features seen in LN, including glomerular leukocyte infiltration, endocapillary proliferation, cellular crescents, fibrinoid necrosis, wire loops, interstitial inflammation, glomerulosclerosis, fibrous crescents, tubular atrophy and interstitial fibrosis.ResultsCompared to traditional renal disease metrics, both urinary angiostatin and VCAM‐1 exhibited outstanding potential (area under the curve 0.97, 0.98, respectively) to predict renal biopsy activity index score ≥ 7, which is associated with poor long‐term prognosis. Whereas urine VCAM‐1 was most significantly associated with fibrous crescents, urine angiostatin was most significantly associated with endocapillary proliferation, cellular crescents, fibrinoid necrosis and fibrous crescents in concurrent renal biopsies.ConclusionUrinary angiostatin and VCAM‐1 are predictive of specific histological changes in concurrent LN renal biopsies. Both urinary biomarkers are good candidates for use as noninvasive measures of renal pathology activity changes in LN.
Generalised joint hypermobility and knee joint hypermobility: prevalence, knee joint symptoms and health‐related quality of life in a Danish adult population
Authors: Junge Tina , Henriksen Peter , Hansen Sebrina , Østengaard Lasse , Golightly Yvonne M. , Juul‐Kristensen Birgit 
Published: October 2017

AbstractAimSeveral biomechanical factors, such as knee joint hypermobility (KJH), are suggested to play a role in the etiology of knee joint symptoms and knee osteoarthritis. Nevertheless, the prevalence or consequences of KJH solely or included in the classification of generalized joint hypermobility (GJHk) is unknown for a general population. Therefore, the objectives were to report the prevalence of self‐reported GJHk and KJH, as well as the association of these conditions to knee joint symptoms, severity and duration of symptoms, and health‐related quality of life (HRQoL) in a Danish adult population.MethodThis study is a cross‐sectional population‐based survey of 2056 Danish adults. Respondents received online questionnaires of GJHk and KJH, knee joint symptoms, the severity and duration of these, as well as HRQoL.ResultsTotal response rate was 49% (n = 1006). The prevalence of self‐reported GJHk and KJH was 13% and 23%, mostly representing women. More than half of the respondents with GJHk and KJH had knee joint symptoms. The odds for reporting knee joint symptoms, severity of knee joint symptoms and duration of knee joint symptoms were twice as high for respondents with GJHk and KJH. Respondents with GJHk and KJH reported lower HRQoL.ConclusionGJHk and KJH were frequently reported in the Danish adult population, mostly in women. Respondents with GJHk and KJH were two times more likely to report knee joint‐related symptoms such as pain, reduced performance of usual activity and lower HRQoL. The impact of these conditions on HRQoL is comparable with knee osteoarthritis.
LEFT—A web‐based tool for the remote measurement and estimation of ecological value across global landscapes
Authors: Long Peter R. , Benz David , Martin Andrew C. , Holland Philip W. A. , Macias‐Fauria Marc , Seddon Alistair W. R. , Hagemann Randi , Frost Tone K. , Simpson Andrew , Power David J. , Slaymaker Mark A. , Willis Kathy J. 
Published: October 2017

Abstract

The overall aim in the development of the Local Ecological Footprinting Tool (LEFT) was to design a web‐based tool that could provide quickly obtained quantitative data on ecological risk to assist landowners when making land‐use change decisions.

The Local Ecological Footprinting Tool works for almost any region in the world and uses freely available satellite imagery, biotic and abiotic data from existing global databases, models and algorithms to deliver a customised report for a selected area within one hour of job submission.

Biotic data automatically obtained for a selected landscape includes terrestrial vertebrate and plant species occurrence data, information on their conservation status and remotely sensed vegetation productivity. Abiotic information obtained includes temperature, precipitation, water availability, insolation, topography, elevation, distribution of urban infrastructure and location of wetlands.

The tool performs a number of analyses on the biotic and abiotic data to produce maps for the selected area at a 30 m resolution depicting land cover type, numbers of globally threatened terrestrial vertebrate and plant species, beta‐diversity of terrestrial vertebrates and plants, habitat intactness, wetland habitat connectivity, numbers of migratory species and vegetation resilience. Results are also aggregated to produce a summary map demonstrating areas of high and low ecological risk across the selected area.

The Local Ecological Footprinting Tool has been designed to be intuitive to use, requiring no specialised software or user expertise. Input is extremely easy and requires the user to highlight the area of interest on a map or using grid co‐ordinates. Output is delivered via the web application and comprises a customised PDF containing the maps and a zip file of geographical information system (GIS) data for the area requested. Users may run an unlimited number of LEFT analyses and download reports free of charge. In addition to the free tool described in this paper, there is also a paid service: individual LEFT analyses can be upgraded for a charge to allow access to the geographically subsetted datasets generated for each report. These data are supplied as a zip file containing raster datasets for the layers in the LEFT analysis in GeoTIFF format. These can be opened and queried in a GIS software package.
Air Ambulance Delivery and Administration of Four‐factor Prothrombin Complex Concentrate Is Feasible and Decreases Time to Anticoagulation Reversal
Authors: Vines Claire , Tesseneer Stephanie J. , Cox Robert D. , Darsey Damon A. , Carbrey Kristin , Puskarich Michael A. 
Published: October 2017

AbstractObjectivesThe objective was to evaluate the feasibility, safety, and preliminary efficacy of four‐factor prothrombin complex concentrate (4‐factor PCC) administration by an air ambulance service prior to or during transfer of patients with warfarin‐associated major hemorrhage to a tertiary care center for definitive management (interventional arm) compared to patients receiving 4‐factor PCC following transfer by air ambulance or ground without 4‐factor PCC treatment (conventional arm).MethodsThis was a retrospective chart review of patients presenting to a large academic medical center. All patients presenting to the emergency department (ED) treated with 4‐factor PCC from April 1, 2014, through June 30, 2016, were identified. For this study, only transfer patients with an International Normalized Ratio (INR) > 1.5 actively treated with warfarin were included. The primary outcome was the proportion of patients with an INR ≤ 1.5 upon tertiary care hospital arrival, and the secondary efficacy outcome was difference in time to achievement of INR ≤ 1.5. Additional safety and efficacy objectives included difference in thromboembolic complications, length of stay, intensive care unit length of stay, and inpatient mortality between groups.ResultsOf the 72 included patients, a higher proportion of patients in the interventional group had an INR ≤ 1.5 on ED arrival (proportion difference = 0.82, 95% confidence interval = 0.64–0.92, p < 0.0001) and significantly reduced time to observed INR ≤ 1.5 (181 minutes vs. 541 minutes, p = 0.001). No differences were observed in thromboembolic complications or patient‐centered outcomes with the exception of mortality, which was significantly higher in patients in the interventional group. This group was also observed to have lower Glasgow Coma Scale score and higher intubation rates prior to transfer and treatment.ConclusionsDispatch of an air ambulance carrying 4‐factor PCC with administration prior to transfer is feasible and leads to more rapid improvement in INR among patients with warfarin‐associated major hemorrhage.
Robotic surgery for the upper gastrointestinal tract: Current status and future perspectives
Authors: Nakauchi Masaya , Uyama Ichiro , Suda Koichi , Mahran Mohamed , Nakamura Tetsuya , Shibasaki Susumu , Kikuchi Kenji , Kadoya Shinichi , Inaba Kazuki 
Published: October 2017

AbstractMore than 4000 da Vinci Surgical Systems have been installed worldwide. Robotic surgery using the da Vinci Surgical System has been increasingly performed in the last decade, especially in urology and gynecology. The da Vinci Surgical System has not become standard in surgery of the upper gastrointestinal tract because of a lack of clear benefits in comparison with conventional minimally invasive surgery. We initiated robotic gastrectomy and esophagectomy for patients with upper gastrointestinal cancer in 2009, and we have demonstrated the potential advantages of the da Vinci Surgical System in reducing postoperative local complications after gastrectomy and recurrent laryngeal nerve palsy after esophagectomy. However, robotic surgery has the disadvantages of a longer operative time and higher costs than the conventional approach. In this review article, we present the current status of robotic surgery for gastric and esophageal cancer, as well as future perspectives on this approach, based on our experience and a review of the literature.