bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sickness Absence and Disability Pension After Breast Cancer Diagnosis: A 5-Year Nationwide Cohort Study
Authors: Kvillemo Pia , Mittendorfer-Rutz Ellenor , Bränström Richard , Nilsson Kerstin , Alexanderson Kristina 
Published: May 2017

Purpose To explore future diagnosis-specific sickness absence and disability pension among women with breast cancer compared with women without breast cancer. Also, to examine associations with disease-related and sociodemographic factors among those with breast cancer. Methods Longitudinal register data on 3,547 women living in Sweden (age 20 to 65 years) who were first diagnosed with breast cancer in 2005, and a matched comparison cohort (n = 14,188), were analyzed for the annual prevalence of diagnosis-specific sickness absence and disability pension over 5 years. Logistic regressions were used to explore associations of disease-related and sociodemographic factors with future sickness absence and disability pension among women with breast cancer. Results Immediately after being diagnosed with breast cancer, the proportion of women with sickness absence was high but decreased continuously from the 1st through 5th year after diagnosis (71%, 40%, 30%, 22%, and 19%, respectively). In comparison, the range for women without breast cancer was 17% to 11%, respectively. The higher prevalence of sickness absence after breast cancer was mainly a result of breast cancer diagnosis, not a mental diagnosis, or other somatic diagnoses. Advanced cancer at diagnosis, > 90 days sickness absence before diagnosis, low education, and being born outside Sweden were associated with higher odds ratios for sickness absence and disability pension (odds ratio range, 1.40 to 6.45). Conclusion The level of sickness absence increased substantially in women with breast cancer during the first year after diagnosis and approached the level of breast cancer–free women in the following years; however, even in the first year, most women were not on sickness absence for a substantial time, and even in high-risk groups, many were not on sickness absence or disability pension in the following years. Information about relatively low future sickness absence and disability pension levels can be used by patients when planning their work, by health care professionals, and by social insurance officers. Employers and Occupational Health Services need this information to adequately handle workplace adjustments.
Hypofractionated Postmastectomy Radiation Therapy Is Safe and Effective: First Results From a Prospective Phase II Trial
Authors: Khan Atif J. , Poppe Matthew M. , Goyal Sharad , Kokeny Kristine E. , Kearney Thomas , Kirstein Laurie , Toppmeyer Deborah , Moore Dirk F. , Chen Chunxia , Gaffney David K. , Haffty Bruce G. 
Published: May 2017

Purpose Conventionally fractionated postmastectomy radiation therapy (PMRT) takes approximately 5 to 6 weeks. Data supporting hypofractionated PMRT is limited. We prospectively evaluated a short course of hypofractionated PMRT, in which therapy was completed in 15 treatment days. Patients and Methods We delivered PMRT at a dose of 36.63 Gy in 11 fractions of 3.33 Gy over 11 days to the chest wall and the draining regional lymph nodes, followed by an optional mastectomy scar boost of four fractions of 3.33 Gy. Our primary end point was freedom from any grade 3 or higher toxicities. We incorporated early stopping criteria on the basis of predefined toxicity thresholds. Results We enrolled 69 women with stage II to IIIa breast cancer, of whom 67 were eligible for analysis. After a median follow-up of 32 months, there were no grade 3 toxicities. There were 29 reported grade 2 toxicities, with grade 2 skin toxicities being the most frequent (16 of 67; 24%). There were two patients with isolated ipsilateral chest wall tumor recurrences (2 of 67; crude rate, 3%). Three-year estimated local recurrence-free survival was 89.2% (95% CI, 0.748 to 0.956). The 3-year estimated distant recurrence-free survival was 90.3% (95% CI, 0.797 to 0.956). Forty-one patients had chest wall reconstructions; three had expanders removed for infection before radiation therapy. The total rate of implant loss or failure was 24% (9 of 38), and the unplanned surgical correction rate was 8% (3 of 38), for a total complication rate of 32%. Conclusion To our knowledge, our phase II prospective study offers one of the shortest courses of PMRT reported, delivered in 11 fractions to the chest wall and nodes and 15 fractions inclusive of a boost. We demonstrated low toxicity and high local control with this schedule. On the basis of our data, we have designed a cooperative group phase III prospective, randomized trial of conventional versus hypofractionated PMRT that will activate soon.
Impact of Expert Pathologic Review of Lymphoma Diagnosis: Study of Patients From the French Lymphopath Network
Authors: Laurent Camille , Baron Marine , Amara Nadia , Haioun Corinne , Dandoit Mylène , Maynadié Marc , Parrens Marie , Vergier Beatrice , Copie-Bergman Christiane , Fabiani Bettina , Traverse-Glehen Alexandra , Brousse Nicole , Copin Marie-Christine , Tas Patrick , Petrella Tony , Rousselet Marie-Christine , Brière Josette , Charlotte Fréderic , Chassagne-Clement Catherine , Rousset Thérèse , Xerri Luc , Moreau Anne , Martin Antoine , Damotte Diane , Dartigues Peggy , Soubeyran Isabelle , Peoch Michel , Dechelotte Pierre , Michiels Jean-François , de Mascarel Antoine , Berger Françoise , Bossard Céline , Arbion Flavie , Quintin-Roué Isabelle , Picquenot Jean-Michel , Patey Martine , Fabre Blandine , Sevestre Henri , Le Naoures Cécile , Chenard-Neu Marie-Pierre , Bastien Claire , Thiebault Sylvie , Martin Laurent , Delage Manuela , Filleron Thomas , Salles Gilles , Molina Thierry Jo , Delsol Georges , Brousset Pierre , Gaulard Philippe 
Published: May 2017

Purpose To prospectively assess the clinical impact of expert review of lymphoma diagnosis in France. Materials and Methods From January 2010 to December 2013, 42,145 samples from patients with newly diagnosed or suspected lymphomas were reviewed, according to the 2008 WHO classification, in real time by experts through the Lymphopath Network. Changes in diagnosis between referral and expert review were classified as major or minor according to their potential impact on patient care. Results The 42,145 reviewed samples comprised 36,920 newly diagnosed mature lymphomas, 321 precursor lymphoid neoplasms, 314 myeloid disorders, and 200 nonhematopoietic neoplasms, with 4,390 benign lesions. There were 4,352 cutaneous and 32,568 noncutaneous lymphomas. The most common mature noncutaneous lymphomas were diffuse large B-cell lymphomas (32.4%), follicular lymphomas (15.3%), classic Hodgkin lymphomas (13%), peripheral T-cell lymphomas (6.3%) of which angioimmunoblastic T-cell lymphomas (2.3%) were the most frequent, and mucosa-associated lymphoid tissue lymphomas (5.8%). A diagnostic change between referral and expert review occurred in 19.7% of patients, with an estimated impact on patient care for 17.4% of patients. This rate was significantly higher for patients sent with a provisional diagnosis seeking expert second opinion (37.8%) than for patients sent with a formal diagnosis (3.7%). The most frequent discrepancies were misclassifications in lymphoma subtype (41.3%), with 12.3% being misclassifications among small B-cell lymphoma entities. Fewer than 2% of changes were between benign and malignant lymphoid conditions. Minor changes (2.3%) mostly consisted of follicular lymphoma misgrading and diffuse large B-cell lymphoma subtype misclassification. Conclusion To our knowledge, this study provides the largest ever description of the distribution of lymphoma entities in a western country and highlights how expert review significantly contributes to a precise lymphoma diagnosis and optimal clinical management in a proportion of patients.
Axiologies: Past and Present Concepts of Literary Value
Authors: Hume Robert D. 
Published: May 2017

AbstractVerdicts concerning a work’s worth, “good,” “bad,” or “great,” vary wildly at any point and change radically over time. Much depends on what didactic or aesthetic rules are imposed and what modes of reading hold sway. Many critics see the purpose of literature as didactic; others subscribe to the principle of art for art’s sake. We need to know whether we are debating a text or disputing the evaluative criteria applicable to it. We need to ask how certain we are of what the author meant to accomplish. Henry Fielding and David Hume remind us that a range of judgments is unavoidable: people differ, and so do aesthetic and moral preferences. So if subjectivity is inescapable, we should accept chaotic diversity in a spirit of courteous toleration.
Density Dependence of Entrepreneurial Dynamics: Competition, Opportunity Cost, or Minimum Efficient Scale?
Authors: Aksaray Gorkem , Thompson Peter 
Published: May 2017

This paper reports on a new examination of the well-established negative effect of localized density on survival in established industries. We attempt to discriminate between three competing, but not necessarily mutually exclusive, explanations: resource competition, variations in the opportunity costs of entrepreneurship, and geographic variations in minimum efficient scale (MES). We construct a model of firm growth and survival in which each of these potential causes of density dependence has a transparent parametric effect, and we derive six predictions that collectively allow for discriminating empirical tests. Empirical results using confidential geocoded data from the National Longitudinal Survey of Youth consistently favor the opportunity cost mechanism.This paper was accepted by Toby Stuart, entrepreneurship and innovation.
Unusual News Flow and the Cross Section of Stock Returns
Authors: Bali Turan G. , Bodnaruk Andriy , Scherbina Anna , Tang Yi 
Published: May 2017

We document that stocks that experience sudden increases in idiosyncratic volatility underperform otherwise similar stocks in the future, and we propose that this phenomenon can be explained by the Miller conjecture [Miller E (1977) Risk, uncertainty, and divergence of opinion. J. Finance 32(4):1151–1168]. We show that volatility shocks can be traced to unusual firm-level news flow, which temporarily increases the level of investor disagreement about the firm value. At the same time, volatility shocks pose a barrier to short selling, preventing pessimistic investors from expressing their views. In the presence of divergent opinions and short-selling constraints, prices initially reflect optimistic views but adjust downward in the future as investors’ opinions converge. The online appendix is available at https://doi.org/10.1287/mnsc.2017.2726 . This paper was accepted by Wei Xiong, finance.
Customer Satisfaction as Mediator Between Website Service Quality and Repurchase Intention: An Emerging Economy Case
Authors: Tandon Urvashi , Kiran Ravi , Sah Ash N. 
Published: May 2017

The purpose of this research is to develop a research model to understand the important dimensions of website service quality and its influence on repurchase intention. The study also analyzes the mediating effect of customer satisfaction on repurchase intention. The results of empirical analysis confirmed that website quality can be conceptualized as a composite of navigation, ease of understanding, information usefulness, website design, ease of use, security and privacy, ease of ordering, and customization. Second, website quality positively affects repurchase intention and customer satisfaction. Third, website service quality can affect repurchase intention by enhancing mediators like customer satisfaction, as it has full mediating effect on repurchase intention. This study has developed the instrument dimensions of website service quality in online shopping context. The study has also refined the scale of repurchase intention by including “cash-on-delivery” (COD) mode of payment as a new dimension to inculcate confidence for online shopping in emerging economies. The online appendix is available at http://dx.doi.org/10.1287/serv.2016.0159 .
The Genesis of Academic Editing: Applying the Process to Critical Editions, Journals, and Volumes
Authors: Tracy Larissa 
Published: May 2017

This essay functions as a response, reflection, and extension of the three preceding articles. The editorial theories elaborated therein, whether “positivist” or “rationalist” (Farrell), authoritative (Koster) or hypertextual (Guthrie) all relate to the practice of academic editing. Each editorial decision, whether in a critical edition, an edited collection, a monograph, or an academic peer-reviewed journal, relies to some extant on putting those theories into practice.
El debido proceso y la cadena de custodia frente a las pruebas judiciales presentadas por el auditor forense
Authors: Plazas Estepas Rodrigo , Hernández Aros Ludivia , Flórez Guzmán Mario 
Published: May 2017

<p>El presente artículo tiene como objetivo relatar el proceso que se debe seguir en la<br />cadena de custodia tal como lo expresa la Ley 906 de 2004 (Congreso de la República<br />de Colombia, 2004), específicamente en un encargo de auditoría forense,<br />lo anterior en razón a que todo proceso de auditoría debe ajustarse a las normas<br />internacionales de auditoría (NIAS), contenidas en el Decreto 2420 de diciembre<br />de 2015 (Presidencia de la República de Colombia, 2015), las cuales garantizan </p><p>eficiencia y eficacia en dicho encargo. De igual forma, dentro de la ejecución de la<br />auditoría forense se debe tener en cuenta la recolección de prueba pericial amplia<br />y suficiente, su grado de legalidad, su autenticidad y el grado actual de aceptación<br />científica, así como la importancia que tiene el debido proceso en la cadena de<br />custodia, lo que permitirá elevar el nivel de confianza de estas en un proceso judicial.</p>
CORRECTION: Adipose derived stem cell transplantation is better than bone marrow mesenchymal stem cell transplantation in treating hindlimb ischemia in mice
Authors: Vu Ngoc Bich , Phi Lan Thi , Dao Thuy Thi-Thanh , Le Ha Thi-Ngan , Ta Van Thanh , Pham Phuc Van 
Published: May 2017

The Figure 5 of the article “Adipose derived stem cell transplantation is better than bone marrow mesenchymal stem cell transplantation in treating hindlimb ischemia in mice” that published in 29 Sept 2016, at Vol 3, Issue 9, from page 844-856 (DOI: 10.7603/s40730-016-0046-0) as below

that lacked the legend for the violet line should be corrected as:

The violet line demonstrated “BM-MSC”.
Respiratory Scores as a Tool to Reduce Bronchodilator Use in Children Hospitalized With Acute Viral Bronchiolitis
Authors: Mussman Grant M. , Sahay Rashmi D. , Destino Lauren , Lossius Michele , Shadman Kristin A. , Walley Susan C. 
Published: May 2017

BACKGROUND AND OBJECTIVES:
Adoption of clinical respiratory scoring as a quality improvement (QI) tool in bronchiolitis has been temporally associated with decreased bronchodilator usage. We sought to determine whether documented use of a clinical respiratory score at the patient level was associated with a decrease in either the physician prescription of any dose of bronchodilator or the number of doses, if prescribed, in a multisite QI collaborative.

METHODS:
We performed a secondary analysis of data from a QI collaborative involving 22 hospitals. The project enrolled patients aged 1 month to 2 years with a primary diagnosis of acute viral bronchiolitis and excluded those with prematurity, other significant comorbid diseases, and those needing intensive care. We assessed for an association between documentation of any respiratory score use during an episode of care, as well as the method in which scores were used, and physician prescribing of any bronchodilator and number of doses. Covariates considered were phase of the collaborative, hospital length of stay, steroid use, and presence of household smokers.

RESULTS:
A total of 1876 subjects were included. There was no association between documentation of a respiratory score and the likelihood of physician prescribing of any bronchodilator. Score use was associated with fewer doses of bronchodilators if one was prescribed (P = .05), but this association disappeared with multivariable analysis (P = .73).

CONCLUSIONS:
We found no clear association between clinical respiratory score use and physician prescribing of bronchodilators in a multicenter QI collaborative.
Partners for Kids Care Coordination: Lessons From the Field
Authors: Weier Rory Cusack , Gardner William , Conkol Kimberly , Pajer Kathleen , Kelleher Kelly J. 
Published: May 2017

OBJECTIVE:
The goal of this trial was to present a case study of care coordination for children and youth with special health care needs from an exclusively pediatric accountable care organization, and compare precare and postcare data on their use of inpatient and emergency department services.

METHODS:
This pre–post comparison of the health care utilization included a subset of 733 children enrolled in Partners for Kids care coordination funded through a delegation arrangement with several Medicaid managed care plans. We compared inpatient admissions, hospital bed days, 30-day hospital readmissions, and emergency department visits during the 6 months before their enrollment in the coordination program versus the 6 months after enrollment.

RESULTS:
Approximately 16 000 referrals to the Partners for Kids care coordination program were made for an estimated 12 000 children. A total of 3072 unique individual children were enrolled; the most common condition classification was mental, behavioral, and neurodevelopmental disorders (25% of enrolled children). Due to rapid turnover/churn in Medicaid managed care eligibility, the subset of children with continuous enrollment was limited to 733 children. Among this subset, the counts of inpatient admissions, bed days, and 30-day readmissions between the pre-enrollment and post-enrollment period decreased (P &lt; .05).

CONCLUSIONS:
These results suggest that it is possible for an accountable care organization to reduce inpatient and emergency department utilization. Going forward, the most important tasks of the care coordination team are to overcome obstacles to referral and participation and to develop methods to achieve better measures of patient-reported outcomes.
Isolation Hope and Threat of Mangrove Restoration Program in Bogowonto Lagoon, Yogyakarta - Indonesia (2002-2014)
Authors: Firaswan Abdullah , Aryandari Rindra , Reza Akbar , Faizah Nur , Rachman Nur , Fitri Ramadhani Aqmarina , Sulthon Andalas Muhammad 
Published: May 2017

<p class="Els-Abstract-text">Bogowonto Lagoon has the largest mangrove ecosystem in southern coast of Yogyakarta, Indonesia. Several activities on mangrove restoration have been conducted to escalate this remnant mangrove forest area. Conversely, rapid increase of shrimp pond area become threat for mangrove ecosystem in Bogowonto lagoon since the early of 21<sup>st</sup> century. Hence, This study is aimed to investigate mangrove composition, distribution and abundance, progress of mangrove restoration program and shrimp pond extensification in 2002 to 2014. Conducted from April 2015 to May 2015, this research consists of several steps namely survey, vegetation analysis, literature study, sociological study using questionnaire, measurement of mangrove and shrimp pond area using Landsat 8 imageries and Arc GIS 10.1. We determined 15 sites along Bogowonto Lagoon using random sampling by quadratic plot (10 m × 10 m for tree, 5 m ×5 m for sapling) and total counts (for seedling). The result showed that there were seven species of mangrove and six species of associate mangrove. <em>Rhizopora mucronata</em> Lamb. was dominant in each growthform with clumped distribution. <em>R. mucronata</em> and <em>Avicennia marina</em> (<a title="Forssk." href="https://en.wikipedia.org/wiki/Forssk.">Forssk.</a>) <a title="Vierh." href="https://en.wikipedia.org/wiki/Vierh.">Vierh.</a> also dominate from backswamp to rivermouth. Satellite imageries revealed that there was a hope due to upward trends of mangrove area in last 12 yr (approximately 5 ha). However, the significant increase sof shrimp pond area (approximately 34 ha) surrounding mangrove area become current and future threat. Based on sociological study, most of people around Bogowonto Lagoon have high awareness, but less participated on mangrove restoration program. Besides, the river mouth covered by sand become another obstacle of it.</p><div><p class="Els-keywords"><em> </em></p><p class="Els-keywords"><em>Keywords:</em> Bogowonto lagoon, mangrove restoration, shrimp pond, vegetation analysis</p></div>
Pun1 Gene Isolation from Capsicum frutescens L. cv Cakra Hijau
Authors: Khasna Elhah Nailul , Zairina Shelly , Juliandari Ria Reinnata , Sulasmi Eko Sri , Listyorini Dwi 
Published: May 2017

<p class="Els-Abstract-text"><em>Capsicum frutescens </em>L. is one of chili peppers with high pungency. <em>Capsicum frutescens </em>has several cultivars, one of those is <em>C. frutescens</em> cv. Cakra Hijau. This cultivars is known resistance to pests and diseases as well. Pungency is due to the accumulation of capsaicinoids. <em>Pun1</em> is an important gene responsible for pungency. The full-leght genomic sequence of <em>Pun1</em> is 1897 bp, containing two exons of 738 bp and 590 bpand one intron of 348 bp in between. This study was aimed to isolate <em>Pun1 </em>gene that free from intron. mRNA was isolated with TriReagentâ furthermore RT-PCR method used Qiagent One-Step RT-PCR and two pairs of primer : F1/R1 (F15’-ATG-GCT-TTT-GCA-TTA-CCA-TCA-3’ / R15’- CTT-AGC-TCG-AAG-TGC-ATC-TA-3’) and F2/R2 (F25’-GAA-GGT-GGC-AGA-AGA-ATC-AG-3’/R25’-TTA-GGC-AAT-GAA-CTC-AAG-GA-3’). The result of this study are isolated 738 bp exon-1 and 590 bp exon 2 of <em>Pun1 </em>gene.</p><div><p class="Els-keywords"><em> </em></p><p class="Els-keywords"><strong>Keywords:</strong> Capsaicin;<em> Capsicum frutescens </em>L. cv. Cakra Hijau; exon; <em>Pun1 </em>gene </p></div>
Sembur Karo: Karo’s Traditional Medicine as Burns Injury Alternative Treatment with Rattus norvegicus as Model
Authors: . Hennisa , Risa Novia , . Juliany , Kelvin Shawn , Kalati Tyas Delilla , Lukitaningsih Raden Rara Endang , Burlakovs Juris 
Published: May 2017

<p class="Els-Abstract-text">Burns injury can be caused by flame, heat, chemical and electricity and it remains as one of the most serious problems in the medical world. Burns injury can be treated with traditional medicine. One of them is <em>Sembur Karo</em>. The objective of this research was to investigate the <em>Sembur Karo</em> potency for burns injury treatment. <em>Sembur Karo</em> obtained from North Sumatera was identified its plant composition and analyzed for bioactive compounds; flavonoid, steroid, and tannin. Twenty five rats (<em>Rattus norvegicus</em>) were used. The rats were divided into five groups of five. The first group used as a control without treatment, the second group are sprayed with <em>Sembur Karo</em>, while the third and the fourth groups were applied with <em>Sembur Karo</em> added with water and human saliva respectively. The last group were treated with Bioplacentone. All treatments were done once a day for 3 wk. Each week, one rat from all group were sacrificed with skins were taken for histology specimen. From this research, it was concluded that bioactive compounds in <em>Sembur Karo</em> were isoquersetin, sterol, and condensed tannin. The skin histology showed that the group which sprayed with <em>Sembur Karo</em> had the most effective effect among all groups.</p><p class="Els-Abstract-text"> </p><div><p class="Els-keywords"><strong>Keywords:</strong> burn injury; burn injury recovery; <em>Sembur Karo</em>.</p></div>