bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developmental delays in emotion regulation strategies in preschoolers with autism
Authors: Nuske Heather J. , Hedley Darren , Woollacott Alexandra , Thomson Phoebe , Macari Suzanne , Dissanayake Cheryl 
Published: July 2017

Children with autism spectrum disorder (ASD) commonly present with difficulty regulating negative emotions, which has been found to impact their behavioral and mental health. Little research has documented the strategies that children with ASD use to regulate their emotion to understand whether they use qualitatively different strategies to children without ASD, whether these are developmentally delayed, or both. Forty‐four children with ASD and 29 typically‐developing children (2–4 years) were given tasks designed to mimic everyday life experiences requiring children to manage low‐level stress (e.g., waiting for a snack) and children's emotion regulation strategies were coded. Parents reported on their child's mental health, wellbeing, and self‐development. The results suggest differences in using emotion regulation strategies in children with ASD, reflecting a delay, rather than a deviance when compared to those used by children without ASD. Only children with ASD relied on their family members for physical and communicative soothing; the typically developing children relied on people outside of their family for help regulating their emotion. More frequent approach/less frequent avoidance was related to a higher self‐evaluation in both groups, but was only additionally related to higher self‐recognition and autonomy in the ASD group. These findings help to identify important emotion regulation intervention targets for this population, including supporting communication with people outside of the family and independence. Autism Res 2017, 10: 1808–1822. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.Lay SummaryResults suggest that children with autism had more difficulty using communication strategies to manage stress only with people outside the family; they used these strategies with family members as often as children without autism. For all children, more task approach/less avoidance was related to children's higher self‐evaluation. These findings suggest targeting communication with people outside of the family and personality development as appropriate intervention goals.
Cover Image, Volume 11, Issue 4
Authors: de Assis Camilla Abbati , Houtman Carl , Phillips Richard , Bilek E.M. (Ted) , Rojas Orlando J. , Pal Lokendra , Peresin Maria Soledad , Jameel Hasan , Gonzalez Ronalds 
Published: July 2017

The cover image, by Camilla Abbati de Assis et al., is based on the Modeling and Analysis Conversion Economics of Forest Biomaterials: Risk and Financial Analysis of CNC Manufacturing, DOI: 10.1002/bbb.1782.
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Mammalian Cell Tissue Culture
Authors: Phelan Katy , May Kristin M. 
Published: July 2017

AbstractCultured mammalian cells are used extensively in the field of human genetics. It requires a number of special skills in order to be able to preserve the structure, function, behavior, and biology of the cells in culture. This unit describes the basic skills required to maintain and preserve cell cultures: maintaining aseptic technique, preparing media with the appropriate characteristics, passaging, freezing and storage, recovering frozen stocks, and counting viable cells. © 2017 by John Wiley & Sons, Inc.
Copy‐Number Variants Detection by Low‐Pass Whole‐Genome Sequencing
Authors: Dong Zirui , Xie Weiwei , Chen Haixiao , Xu Jinjin , Wang Huilin , Li Yun , Wang Jun , Chen Fang , Choy Kwong Wai , Jiang Hui 
Published: July 2017

AbstractEmerging studies have demonstrated that whole‐genome sequencing (WGS) is an efficient tool for copy‐number variants (CNV) detection, particularly in probe‐poor regions, as compared to chromosomal microarray analysis (CMA). However, the cost of testing is beyond economical for routine usage and the lengthy turn‐around time is not ideal for clinical implementation. In addition, the demand for computational resources also reduces the probability of clinical integration into each laboratory. Herein, a protocol providing CNV detection from low‐pass, whole‐genome sequencing (0.25×) in a clinical laboratory setting is described. The cost is reduced to less than $200 USD per sample and the turn‐around time is within an acceptable clinically workable time‐frame (7 days). © 2017 by John Wiley & Sons, Inc.
Cataglyphis: An autonomous sample return rover
Authors: Gu Yu , Ohi Nicholas , Lassak Kyle , Strader Jared , Kogan Lisa , Hypes Alexander , Harper Scott , Hu Boyi , Gramlich Matthew , Kavi Rahul , Watson Ryan , Cheng Marvin , Gross Jason 
Published: July 2017

AbstractThis paper presents the design of Cataglyphis, a research rover that won the NASA Sample Return Robot Centennial Challenge in 2015. During the challenge, Cataglyphis was the only robot that was able to autonomously find, retrieve, and return multiple types of samples in a large natural environment without using Earth‐specific sensors such as GPS and magnetic compasses. It navigates through a fusion of measurements collected from inertial sensors, wheel encoders, a nodding Lidar, a set of ranging radios, a camera on a panning platform, and a sun sensor. In addition to visual detection of a homing beacon, computer vision algorithms provide the sample detection, identification, and localization capabilities, with low false positive and false negative rates demonstrated during the competition. The mission planning and control software enables robot behaviors, determines sequences of actions, and helps the robot to recover from various failure conditions. A compliant, under‐actuated manipulator conforms to the natural terrain before picking up samples of various size, weight, and shape.
Concise Review: The Deleterious Effects of Cigarette Smoking and Nicotine Usage and Mesenchymal Stem Cell Function and Implications for Cell-Based Therapies
Authors: Greenberg Jordan M. , Carballosa Carlos M. , Cheung Herman S. 
Published: July 2017

Abstract
Stem cell sources for cell-based therapeutics are often screened for infectious agents and genetic diseases prior to implantation; however, there are other risk factors that are often overlooked, which may ultimately lead to less efficacious clinical outcomes. One such risk factor is exposure of mesenchymal stem cells (MSCs) to cigarette smoke or nicotine. Recent data have shown that exposure to cigarette smoke or nicotine leads to decreased regenerative potential, namely decreased proliferation, decreased migration, and decreased differentiation potential of exposed MSCs. This review provides a brief introduction into MSCs and their respective niches and a summary regarding the interactions of cigarettes and nicotine with MSCs populations. Specifically, the effects of cigarette smoke and nicotine on the regenerative potential of MSCs (i.e., proliferation, migration, and differentiation) will be covered with an emphasis on considerations for the development of future cell-based clinical trials and therapies.
Facile Synthesis and Self‐Cleaning Application of Bimetallic (CuSn, CuNi) Dendrites
Authors: Biswas Anupam , Kulkarni Mayuresh A. , Bakthavatsalam Rangarajan , Mondal Sourik , Dwivedi Pravin K. , Shelke Manjusha V. , Devi Radhamonyamma N. , Banpurkar Arun G. , Kundu Janardan 
Published: July 2017

AbstractBimetallic dendrites (Au, Ag, Pt, Pd) have received intense research interest due to their applications in catalysis and sensing. However, reports on rational synthesis of non‐noble bimetallic dendrites that finds self‐cleaning applications are scanty. Here, we demonstrate one step co‐reduction based galvanic replacement reaction (GRR) for synthesis of alloyed bimetallic dendrites (CuSn, CuNi) with controlled surface roughness and chemical composition. Probing their growth process reveals that i) for CuSn dendrites, co‐reduction of Cu2+ and Sn2+ is observed throughout GRR; ii) for CuNi dendrites, Cu nanoparticle, that deposits initially, augments the reduction of Ni2+ which leads to CuNi alloy phase formation during later stages of GRR. These dendrites, naturally having dual degree of surface roughness (micro/nano), have been exploited here for fabricating superhydrophobic surfaces (SHS) with excellent self‐cleaning abilities. They show enabling properties such as high contact angle, minimal contact angle hysteresis, and excellent Cassie state stability with no impalement. They maintain superhydrophobicity when exposed to different environmental conditions (low temperature, high temperature, exposure to corroding solutions and UV radiation). The present facile methodology for fabrication of bimetallic dendrites is beneficial for low‐cost production of functional nano/micro‐materials.
The Significant Role of NiO in Enhancing the Electrocatalytic Activity of the Pyrolysis Products of the Mixture Containing PdO and Multiwalled Carbon Nanotubes for EOR
Authors: Ding Keqiang , Zhang Yan , Wei Binjuan , Shi Xiaomi , Li Chenxue , Pan Junqing 
Published: July 2017

AbstractA novel finding, that the pyrolysis products of the mixture containing NiO, PdO and multi‐walled carbon nanotubes (MWCNTs) (denoted as PdxNiy/MWCNTs), as compared to the system having only PdO and MWCNTs, have significant electrocatalytic activity for ethanol oxidation reaction (EOR), is reported for the first time in this work. The effects of the atomic ratio of Pd to Ni on the physicochemical properties of the synthesized PdxNiy/MWCNTs composites are basically investigated by using X‐ray diffraction (XRD), scanning electron microscopy (SEM) and X‐ray photoelectron spectroscopy (XPS). XRD results indicate that the crystallinities of the prepared catalysts are closely related to the atomic ratio of Pd to Ni. SEM observations reveal that the morphologies of the synthesized catalysts are also strongly affected by the atomic ratio of Pd to Ni. The electrocatalytic activity of the prepared PdxNiy/MWCNTs materials towards EOR is examined, and the results demonstrate that the best electrocatalytic activity for EOR is exhibited by the catalyst with an atomic ratio of Pd to Ni 1:1. Showing the fact, that the pyrolysis product of the mixture having PdO and NiO and MWCNTs has excellent electrocatalytic activity for EOR, is the main contribution of this work, which is believed to have developed a novel cost‐effective electrocatalyst for EOR. Abstract Text, 800‐1000 characters.
Addressing Unintended Instructional Messages About Repeated Reading
Authors: Frey Nancy , Fisher Douglas 
Published: July 2017

AbstractThe authors analyzed 88 classroom observations to determine whether there were actions that teachers were taking to send a message to students that rereading was not valuable. They identified three practices during shared reading, guided reading, and independent reading that telegraphed messages to students against rereading. The authors also observed teachers building repeated reading into their instruction as they changed the purpose, asked really good questions, pressed for evidence, and provided an audience for students.
A Report on Ten Asia Pacific Countries on Current Status and Future Directions of the Genetic Counseling Profession: The Establishment of the Professional Society of Genetic Counselors in Asia
Authors: Laurino Mercy Y. , Leppig Kathleen A. , Abad Peter James , Cham Breana , Chu Yoyo Wing Yiu , Kejriwal Saahil , Lee Juliana M. H. , Sternen Darci L. , Thompson Jennifer K. , Burgess Matthew J. , Chien Shu , Elackatt Niby , Lim Jiin Ying , Sura Thanyachai , Faradz Sultana , Padilla Carmencita , Paz Eva Cutiongco de‐la , Nauphar Donny , Nguyen Khanh Ngoc , Zayts Olya , Vu Dung Chi , Thong Meow‐Keong 
Published: July 2017

AbstractThe Professional Society of Genetic Counselors in Asia (PSGCA) was recently established as a special interest group of the Asia Pacific Society of Human Genetics. Fostering partnerships across the globe, the PSGCA's vision is to be the lead organization that advances and mainstreams the genetic counseling profession in Asia and ensures individuals have access to genetic counseling services. Its mission is to promote quality genetic counseling services in the region by enhancing practice and curricular standards, research and continuing education. The PSGCA was formally launched during the Genetic Counseling Pre‐Conference Workshop held at the 11th Asia‐Pacific Conference on Human Genetics in Hanoi, Viet Nam, September 16, 2015. The pre‐conference workshop provided an opportunity for medical geneticists and genetic counselors from across 10 Asia Pacific countries to learn about the varied genetic counseling practices and strategies for genetic counseling training. This paper provides an overview of the current status and challenges in these countries, and proposed course of unified actions for the future of the genetic counseling profession.
Cut and rip and cut alone techniques versus usual practice in the removal of trauma patient clothing
Authors: Sibley Aaron K. , Jain Trevor N. , Nicholson Brent , Atkinson Paul 
Published: July 2017

AbstractIntroductionRapid exposure of a trauma patient is an essential component of the primary survey. No gold standard exists regarding the best technique to remove clothing from a trauma patient. The purpose of this study is to compare two techniques of clothing removal versus usual practice using standard trauma shears.MethodsAdvanced Care Paramedic (ACP) students were randomized to either the Cut and Rip (CAR) or Cut Alone (CAL) techniques to remove clothing from a standardized trauma mannequin. Practicing paramedics were recruited to remove clothing from the mannequin using Usual Practice (UP). Total time and time for removal of individual pieces of clothing was recorded.ResultsTwenty-four participants (8 per group) were recruited to participate. The student groups (CAR, CAL) were similar in mean age (29, 27), years of practice (1 student >5 years) and male gender (63, 43%). The UP group was older (mean 34), more experienced (63% practice >5 years), and had a higher level of training (63% ACP) but a similar percentage of males (63%). Removal time was significantly less in the CAR group compared to the CAL group (mean 104 seconds, 95% CI 88–120 vs. mean 136 seconds, 95% CI 119–154, p=0.02). Removal times in the UP group were not significantly different from the other groups (mean 124 seconds, 95% CI 108–140, p>0.05).ConclusionThe CAR technique is faster than both CAL and UP groups to remove clothing from a standard trauma mannequin.
Patronage and health care in eighteenth-century Irish county infirmaries
Authors: Grace Pierce 
Published: July 2017

AbstractThe creation of a network of county infirmaries was a remarkable achievement in late eighteenth-century Ireland. Supported by grants from parliament and the county grand juries, each hospital was managed by governors whose subscriptions entitled them to appoint the medical staff and decide on the patient population. While the laudable aim of the legislators was that the infirmaries would be ‘a means of restoring the health and preserving the lives of many’, the reality was quite different. In 1788 the prison reformer, John Howard, and the inspector general of prisons, Sir Jeremiah Fitzpatrick, delivered a damning report to parliament on the state of the county infirmaries. They described good care and governance in a minority of institutions, but most were in a very bad state; they noted decayed and broken buildings, dirty or no bedding, poor food, lack of regulation, financial malfeasance, few patients and absent staff. Based on their report, this paper argues that the county infirmaries benefited the governors and the staff considerably, and had little impact on the health of the nation. However, providing a hospital and trained medical professionals in every county was a significant step in the formation of the Irish institutional healthcare system.
The laboratory for ‘scientific history’: T. W. Moody and R. D. Edwards at the Institute of Historical Research
Authors: Hayton D. W. 
Published: July 2017

AbstractThe point of origin of the ‘Irish historiographical revolution’ initiated by T. W. Moody and R. D. Edwards in the 1930s, which issued, among other things, in the foundation of Irish Historical Studies, is customarily located in their experiences together as research students in London University’s Institute of Historical Research. Hitherto, we have known little or nothing of those experiences beyond the recollections of the two principals themselves. This article uses the Institute’s own archive, and other contemporary documentary evidence, including surviving letters from Moody to Edwards, to elucidate the precise influence of the Institute and its staff in moulding their outlook. Rather than asserting some form of ideological indoctrination – for example in propagating an ethos of ‘value-free’ history writing – it argues that what was important was the example of the Institute’s institutional structures (including its Bulletin), which Moody and Edwards determined to replicate in Ireland; and that these structures, emphasising collaboration between historical researchers in pursuit of a common purpose, were themselves of the first importance in influencing the aspiration to create an Irish history free from confessional bias and overt expressions of political prejudice.
‘In what orbit we shall find ourselves, no one could predict’: institutional reform, the university merger and ecclesiastical influence on Irish higher education in the 1960s
Authors: Nolan Ann , Walsh John 
Published: July 2017

AbstractThis paper explores the persistence of ecclesiastical influence on higher education in Ireland during an era of far-reaching policy change in the 1960s. The extensive interaction between political and official elites and the Catholic bishops offers a fascinating insight into the complex and contested process of policy formulation during an era of transformation in higher education. This study offers a re-interpretation of Whyte’s thesis that the Irish bishops displayed a ‘new flexibility’ in their response to governmental policy initiatives during this period, especially the initiative for university merger launched by Donogh O’Malley in 1967. Catholic prelates, notably John Charles McQuaid, the influential archbishop of Dublin, were pursuing a traditional Catholic religious and socio-political agenda in higher education, which sought not so much to accommodate new official initiatives as to shape such reforms in the ideological direction favoured by the bishops. McQuaid in particular enjoyed exceptional access to policy-makers and was an indispensable partner in launching the initiative for the university merger. The eventual failure of the merger, which was influenced by the successful resistance of academic elites and the declining significance of religious divisions in higher education, underlined the limits of ecclesiastical power in a rapidly changing society.
Treatment rates for the pox in early modern England: a comparative estimate of the prevalence of syphilis in the city of Chester and its rural vicinity in the 1770s
Authors: SZRETER SIMON 
Published: July 2017

ABSTRACTThis article offers an innovative attempt to construct an empirically-based estimate of the extent of syphilis prevailing in two contrasting populations in late eighteenth-century Britain. Thanks to the co-incident survival of both a detailed admissions register for Chester Infirmary and a pioneering census of the city of Chester in 1774 taken by Dr John Haygarth, it is possible to produce age-specific estimates of the extent to which adults of each sex had been treated for the pox by age 35. These estimates can be produced both for the resident population of Chester city and comparatively for the rural region immediately surrounding Chester. These are the first estimates of the prevalence of this important disease produced for the eighteenth century and they can be compared with similar figures for England and Wales c. 1911–1912.
Arterial switch operation in patients with transposition and a left-sided aorta
Authors: Talwar Sachin , Anderson Robert H. , Ramakrishnan Pradeep , Bhoje Amolkumar , Gupta Saurabh , Choudhary Shiv Kumar , Airan Balram 
Published: July 2017

AbstractObjectivesArterial switch operation is the treatment of choice in infants with transposed arterial trunks. It is technically challenging to perform in patients having usual atrial arrangement and concordant atrioventricular connections but having a left-sided aorta. Correction in this setting requires surgical expertise and precision. Here we review our experience with such patients.MethodsBetween January, 2002 and October, 2013, the arterial switch operation was performed in 20 patients in the combination emphasised above. Patient records were analysed in detail for coronary arterial patterns, and for the techniques used for transfer of the coronary arteries and reconstruction of the great arteries. Outcomes were recorded in terms of in-hospital survival and left ventricular function at the most recent follow-up.ResultsAll patients survived the procedure. Ages ranged from 3 days to 18 months, with a median of 75 days; the weight of the patients ranged from 3 to 8.8 kg, with a median of 3.85 kg. The LeCompte manoeuvre was performed in only nine patients. The mean cardiopulmonary bypass time was 157.5±24.9, with a median of 161 minutes, and the mean aortic cross-clamp time was 101.2±23.8, with a median of 102 minutes. Subsequently, two patients died: the first due to a sudden onset of ventricular fibrillation and the second during a crisis of severe pulmonary hypertension. At the last follow-up, which ranged from 23 to 41 months, with a mean of 38.04±2.32 and a median of 38.4 months, all 18 survivors were in NYHA class I, with none requiring cardiac medications and all having normal bi-ventricular function without residual defects.ConclusionWith appropriate technical modifications, patients with concordant atrioventricular and discordant ventriculo-arterial connections with a left-sided aorta can undergo successful anatomical repair.
Optimised chronic infection models demonstrate that siderophore ‘cheating’ in Pseudomonas aeruginosa is context specific
Authors: Harrison Freya , McNally Alan , da Silva Ana C , Heeb Stephan , Diggle Stephen P 
Published: July 2017

Abstract
The potential for siderophore mutants of Pseudomonas aeruginosa to attenuate virulence during infection, and the possibility of exploiting this for clinical ends, have attracted much discussion. This has largely been based on the results of in vitro experiments conducted in iron-limited growth medium, in which siderophore mutants act as social ‘cheats:’ increasing in frequency at the expense of the wild type to result in low-productivity, low-virulence populations dominated by mutants. We show that insights from in vitro experiments cannot necessarily be transferred to infection contexts. First, most published experiments use an undefined siderophore mutant. Whole-genome sequencing of this strain revealed a range of mutations affecting phenotypes other than siderophore production. Second, iron-limited medium provides a very different environment from that encountered in chronic infections. We conducted cheating assays using defined siderophore deletion mutants, in conditions designed to model infected fluids and tissue in cystic fibrosis lung infection and non-healing wounds. Depending on the environment, siderophore loss led to cheating, simple fitness defects, or no fitness effect at all. Our results show that it is crucial to develop defined in vitro models in order to predict whether siderophores are social, cheatable and suitable for clinical exploitation in specific infection contexts.