bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic review of ectopic pregnancy after hysterectomy
Authors: Shao Emily X. , Hopper Kendra , McKnoulty Matthew , Kothari Alka 
Published: November 2017

AbstractBackgroundAn ectopic pregnancy after hysterectomy is a rare but potentially life‐threatening event. Women with this condition might not be appropriately investigated, resulting in delays in diagnosis and treatment.ObjectivesTo characterize cases of ectopic pregnancy occurring after hysterectomy.Search strategyPubMed, Embase, Scopus, and Web of Science were searched using the terms “pregnancy, abdominal” or “pregnancy, tubal” or “pregnancy, ectopic” and “hysterectomy” or “post‐hysterectomy” or “post hysterectomy.”Selection criteriaCase reports or case series published in English up to October 10, 2016, were included. Patients were included if the diagnosis was confirmed by definitive tests such as serum or urine β‐human chorionic gonadotropin (β‐hCG) testing, ultrasonography evidence of pregnancy, or histology.Data collection and analysisPatient characteristics were extracted via a standard spreadsheet.Main resultsA total of 57 patients were included in the analysis. Abdominal pain was the predominant symptom. Implantation in a remaining fallopian tube was common. Most patients were managed surgically.ConclusionsA high index of suspicion and a low threshold for performing a β‐hCG pregnancy test is recommended in all women presenting with clinical symptoms of ectopic pregnancy, regardless of the hysterectomy status. This could lead to earlier diagnosis and fewer complications.
A relaxation of the strong Bordeaux Conjecture
Authors: Huang Ziwen , Li Xiangwen , Yu Gexin 
Published: November 2017

AbstractLet be k nonnegative integers. A graph G is ‐colorable if the vertex set can be partitioned into k sets , such that the subgraph , induced by , has maximum degree at most for . Let denote the family of plane graphs with neither adjacent 3‐cycles nor 5‐cycles. Borodin and Raspaud (2003) conjectured that each graph in is (0, 0, 0)‐colorable (which was disproved very recently). In this article, we prove that each graph in is (1, 1, 0)‐colorable, which improves the results by Xu (2009) and Liu‐Li‐Yu (2016).
Anatomy and histology of the prostate and glands of Cowper in three species of neotropical bats
Authors: Miotti María Daniela , Mollerach Marcos I. , Barquez Ruben M. 
Published: November 2017

AbstractThe reproductive accessory glands (RAG) are essential components in reproduction because their secretion products ensure survival, viability, and sperm motility. The objective of this study was to characterize and compare the morphological and histological structure of the RAG in three species of bats of the genusSturnira(S. erythromos, S. lilium, andS. oporaphilum). The RAG complex comprise a compact gland (prostate), which surrounds the urethra, and a pair of Glands of Cowper at the base of penis. Anatomical and histologically, the prostate are differentiated in two regions, ventral and dorsal. The dorsal region has tubuloalveolar glands with secretions fine granular or accumulations of a gel‐like substance with bubbles and the ventral region, has alveolar glands with secretory cells form a single‐layer of small cells. The seminal vesicles are absent. The prostatic morphology of the three species is similar to that of other studied Stenodermatinae and Desmodontinae, but differs from other subfamilies of Phyllostomidae (Carollinae, Glossophaginae, and Phyllostominae) as that of Molossidae and Vespertilionidae. The RAG complex has no annual variation in relation to functionality or size, but it is variable depending on age (subadults and adults). This agrees with the annual reproductive pattern described for these species in these latitudes, where adult males are reproductively active throughout the year.
Clinical studies in CRS and HIPEC: Trials, tribulations, and future directions—A systematic review
Authors: Morano William F. , Khalili Marian , Chi Dennis S. , Bowne Wilbur B. , Esquivel Jesus 
Published: November 2017

BackgroundThe field of cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) has suffered from a lack of clinical trials to validate its expanding use.ObjectiveTo evaluate published and ongoing clinical trials seeking to better define role of CRS/HIPEC in the treatment of peritoneal surface malignancies.MethodsSystematic review by PubMed search was performed using terms “Clinical trial,” “intraperitoneal chemotherapy,” and “HIPEC.”ClinicalTrials.govand EudraCT registries were searched for active clinical trials. Eligibility included CRS/HIPEC trials investigating adult patient populations from published clinical reports and/or trials currently accruing or at completion.ResultsThirteen published trials and 57 active clinical trials were included for review.ConclusionsPublished and ongoing U.S. and international clinical trials for CRS and HIPEC are defining important parameters that include improving patient selection, strategic sequences of treatment, cytoreductive strategies, chemotherapeutics, optimal hyperthermic temperature and timing, and toxicity profiles. Main barriers or limitations to trial development remain patient enrollment, trial design, and oncologic community collaboration. Overall progress is positive with increasing number of clinical trials throughout the world. Collaboration between surgeons and the wider oncologic community will be crucial to validate this important treatment strategy.
The impact of visceral adipose tissue amount on the adequacy of lymph node retrieval in colorectal cancer surgery
Authors: Choe Eun Kyung , Park Kyu Joo , Ryoo Seung‐Bum , Moon Sang Hui , Oh Heung‐Kwon , Han Eon Chul , Kwon Yoon‐Hye 
Published: November 2017

BackgroundObesity is increasing worldwide, potentially influencing surgical outcomes in colorectal cancer (CRC) patients. We analyzed the effects of obesity indexes on lymph node (LN) retrieval in CRC patients.MethodWe applied obesity indexes of body mass index (BMI) and visceral (VAT) and subcutaneous (SAT) adipose tissue volumes to stage I‐III CRC patients. The primary outcome was the effect of these indexes on the number of retrieved LNs (12 > LNs ≥ 12).ResultsAmong 519 patients, 35.6% had a BMI ≥ 25 kg/m2. After adjusting for gender, age, tumor location, resected colon length, and local invasion and LN statuses, patients in the highest VAT quartile showed a 5.848 decrease in the number of retrieved LNs, with an odds ratio of 0.483 (95% confidence interval [CI] 0.260‐0.8979) for adequate LN retrieval (≥12), compared with those in the lowest quartile (P < 0.001 for both). Analysis of the model predicting LN retrieval revealed VAT as the only obesity index (area under the curve [AUC] = 0.721) providing significant additional predictive power (P = 0.037) to the model including age, gender, staging, tumor location, and resected colon length (AUC = 0.707).ConclusionIncreased VAT may cause inadequate LN retrieval in CRC patients. In viscerally obese patients, VAT volumes should be considered when clinically interpreting LN status.
Prediction of cognitive worsening in de novo Parkinson's disease: Clinical use of biomarkers
Authors: Arnaldi Dario , De Carli Fabrizio , Famà Francesco , Brugnolo Andrea , Girtler Nicola , Picco Agnese , Pardini Matteo , Accardo Jennifer , Proietti Luca , Massa Federico , Bauckneht Matteo , Morbelli Silvia , Sambuceti Gianmario , Nobili Flavio 
Published: November 2017

AbstractBackgroundCognitive impairment is a frequent and disabling feature of Parkinson's disease. Identifying the factors able to predict cognitive worsening since the early stage may improve disease management. The objective of this study was to define the best predictors of future cognitive worsening in a group of patients with newly diagnosed PD and to propose cutoff values potentially useful at the individual level.MethodsFifty‐four consecutive drug‐naive patients with de novo PD were prospectively evaluated by clinical and neuropsychological assessment, resting EEG, and 123I‐FP‐CIT‐SPECT and clinically classified into mainly motor, diffuse/malignant, and intermediate PD subtypes; they were then followed up for an average of 5 years. Cognitive outcome was defined by identifying cognitively stable or worsened patients.ResultsStep‐wise logistic regression selected the posterior qEEG mean frequency and 123I‐FP‐CIT‐SPECT uptake at caudate level (P < 0.0001). The posterior qEEG mean frequency (cut point, 8.3 Hz) and the caudate 123I‐FP‐CIT‐SPECT uptake (cut point, 2.3, specific to nondisplaceable binding ratio) achieved 82% and 80% of accuracy, respectively, in predicting cognitive outcome. Survival analysis showed decreasing expected time to cognitive worsening associated with scores below the established thresholds for qEEG and 123I‐FP‐CIT‐SPECT and with the presence of a malignant clinical phenotype.ConclusionsResting EEG and 123I‐FP‐CIT‐SPECT are good predictors of future cognitive worsening, in de novo drug‐naive PD patients. Wherever available, these biomarkers could add valuable prognostic information to classification into different clinical phenotypes. © 2017 International Parkinson and Movement Disorder Society
The cerebral basis of Parkinsonian tremor: A network perspective
Authors: Helmich Rick C. 
Published: November 2017

ABSTRACTTremor in Parkinson's disease is a poorly understood sign. Although it is one of the clinical hallmarks of the disease, its pathophysiology remains unclear. It is clear that tremor involves different neural mechanisms than bradykinesia and rigidity, the other core motor signs of Parkinson's disease. In particular, the role of dopamine in tremor has been heavily debated given clinical observations that tremor has a variable response to dopaminergic medication. From a neuroscience perspective, tremor is also a special sign; unlike other motor signs, it has a clear electrophysiological signature (frequency, phase, and power). These unique features of tremor, and newly available neuroimaging methods, have sparked investigations into the pathophysiology of tremor. In this review, evidence will be discussed for the idea that parkinsonian tremor results from increased interactions between the basal ganglia and the cerebello‐thalamo‐cortical circuit, driven by altered dopaminergic projections to nodes within both circuits, and modulated by context‐dependent factors, such as psychological stress. Models that incorporate all of these features may help our understanding of the pathophysiology of tremor and interindividual differences between patients. One example that will be discussed in this article is the “dimmer‐switch” model. According to this model, cerebral activity related to parkinsonian tremor first arises in the basal ganglia and is then propagated to the cerebello‐thalamo‐cortical circuit, where the tremor rhythm is maintained and amplified. In the future, detailed knowledge about the architecture of the tremor circuitry in individual patients (“tremor fingerprints”) may provide new, mechanism‐based treatments for this debilitating motor sign. © 2017 International Parkinson and Movement Disorder Society
Ductile damage modelling with locking‐free regularised GTN model
Authors: Zhang Yi , Lorentz Eric , Besson Jacques 
Published: November 2017

SummaryThe major goal of this work is to develop a robust modelling strategy for the simulation of ductile damage development including crack initiation and subsequent propagation. For that purpose, a Gurson‐type model is used. This model class, as many other damage models, leads to significant material softening and must be used within a large deformation framework due to the ductile character of the materials. This leads to 2 main difficulties that should be dealt with carefully: mesh dependency and volumetric locking. In this work, a logarithmic finite strain framework is adopted in which the Gurson‐Tvergaard‐Needleman constitutive law is reformulated. Then a nonlocal formulation with regularisation of hardening variable is applied so as to solve mesh dependency and strain localization problem. In addition, the nonlocal model is combined with mixed “displacement‐pressure‐volume variation” elements to avoid volumetric locking. Thereby, a mesh‐independent and locking‐free finite strain framework suitable for the modelling of ductile rupture is established. Attention is paid to mathematical properties and numerical performance of the model. Finally, the model parameters are identified on an experimental database for a nuclear piping steel. Simulations of standard test specimens (notched tensile bars and compact tension and single edge notched tensile cracked specimens) are performed and compared to experimental results.
The use of fetal neurosonography and brain MRI in cases of cytomegalovirus infection during pregnancy: A retrospective analysis with outcome correlation
Authors: Birnbaum Roee , Ben‐Sira Liat , Lerman‐Sagie Tally , Malinger Gustavo 
Published: November 2017

AbstractObjectiveTo analyze ultrasound (US) and magnetic resonance imaging (MRI) results and developmental outcome in cases of maternal primary cytomegalovirus (CMV) infection during pregnancy.MethodsWe retrospectively reviewed the results of fetal neurosonography and brain MRI of CMV‐infected fetuses (Group 1). Cases of maternal infection in which the fetal status was unknown, and subsequently had a negative CMV postnatal urine analysis, were independently analyzed (Group 2). Imaging results were classified as follows: positive, negative, or inconclusive. Developmental landmarks were followed up.ResultsEighty‐one women were included in the study: 48 (59.2%) in Group 1 and 33 (40.8%) in Group 2. In Group 1, termination of pregnancy was performed in 8 cases (16.7%) following the diagnosis of brain abnormalities. Among the remaining cases, concordance rate between US and MRI was 78%. False negative rates for US and MRI were 5.5% and 6.4%, respectively (hearing deficits). For MRI, we found 17.5% of false positive/inconclusive results, while for the US, we found 5% of inconclusive results. In Group 2, false positive rates for US and MRI were 6.5% and 12.9%, respectively.ConclusionsAdding MRI in CMV‐infected cases with a normal neurosonographic follow‐up should be weighed against a nonnegligible rate of false positive and inconclusive findings.
MRI and US in the evaluation of fetal anomalies: The need to work together
Authors: Bernardo S. , Giancotti A. , Antonelli A. , Rizzo G. , Vinci V. , Pizzuti A. , Catalano C. , Manganaro L. 
Published: November 2017

AbstractPurposeReal‐time virtual sonography (RVS) is a new technique that synchronizes real‐time ultrasonography (US) and multiplanar reconstructed magnetic resonance imaging (MRI). The purpose of this study was to evaluate the feasibility and ability of RVS to assess the main pathologies in fetuses with suspected US anomalies.Method and MaterialsReal‐time virtual sonography (Hitachi, HI VISION Ascendus) was offered to 30 patients who had undergone fetal MRI. The acquired MRI image dataset was loaded into the fusion system and displayed together with the real‐time US image. The ability of RVS to assess the main anatomical sites and fetal anomalies was evaluated.ResultsReal‐time virtual sonography was technically possible in all cases. From a total of 30 patients, RVS helped the diagnosis in 10 cases. In 15 cases of encephalic pathology, fusion imaging improved the accuracy of the diagnosis; in the other 5 cases, MRI was superior to US even when using the RVS.ConclusionThis is a study on the feasibility and practical use of RVS. Thanks to information from both US and MRI, RVS allowed better identification of the fetal pathologies and improved the performance of the ultrasound examination. In our experience, it was really helpful in pathologies that would benefit from US follow‐up.
Long‐term changes in the ground thermal regime of an artificially drained thaw‐lake basin in the Russian European north
Authors: Kaverin Dmitry A. , Melnichuk Evgeniy B. , Shiklomanov Nikolay I. , Kakunov Nikolay B. , Pastukhov Alexander V. , Shiklomanov Alexey N. 
Published: November 2017

AbstractLong‐term (1982–1995) observations of the ground thermal regime of a drained thaw‐lake basin in the Pechora Lowlands of the Russian European north revealed a high spatial and temporal variability in the ground temperature response to artificial drainage. The thermal response was controlled by the atmospheric climate and by evolution of the landsurface following drainage. Observed changes in permafrost conditions were related to three climatic subperiods identified from air and ground temperature trends. The first (1982–1984) was characterized by gradual ground cooling associated with partial formation of permafrost patches under the initial stage of formation of marshy meadows. The second (1985–1987) involved strong ground cooling, resulting in the formation of a subsurface permafrost layer beneath most of the basin. The third (1988–1995) was marked by a gradual increase in annual mean ground temperature, promoting partial permafrost degradation under marshy meadows and willow stands. Initially, newly aggraded permafrost remained under peat mounds and tundra meadows. The spatial pattern of permafrost change can be attributed to heterogeneous landsurface evolution and variable snow thickness. Four distinct ground temperature regimes are distinguished: (i) thawed ground, (ii) deep permafrost, (iii) unstable permafrost and (iv) stable permafrost.
Screening Commercial Semiconductors for Visible Light Driven Asymmetric Catalysis
Authors: Zhang Yin , Zhu Yanfei , Zhou Wencai , Qiu Xueying , Tang Zhiyong 
Published: November 2017

AbstractTo find cheap and commercially available materials that are efficient in the catalytic process is of paramount importance for practical application in both chemical and biomedical engineering. As‐purchased nanosized semiconductors are systematically investigated as catalysts in visible light driven asymmetric reactions with the help of chiral ligands. Significantly, among varied semiconductors, WO3 exhibits the best performance with 91% enantiomeric excess and 95% conversion ratio.
Preparation, Characterisation and Performance of Microencapsulated Red Phosphorus
Authors: Liu J. , Guan H. 
Published: November 2017

AbstractMicroencapsuled red phosphorus (MRP), with a phenolic resin coating layer, was successfully prepared. It was characterized by Fourier‐transform infrared spectroscopy (FTIR) and Scanning electron microscope (SEM). Meanwhile its water absorption, thermostability, thermodynamic properties and critical ignition temperature (Tb) have been studied. The results show that the MRP which is coated with phenolic resin can decrease the water absorption, increase thermostability and critical ignition temperature (Tb) significantly, compared with red phosphorus (RP). The thermodynamic properties which include apparent activation energy (E), pre‐exponential factor (A), activation entropy (ΔS#), activation enthalpy (ΔH#) and Gibbs free energy (ΔG#) of RP and MRP are obtained. Moreover, the MRP can reduce the water absorption and friction sensitivity of red phosphorus smoke agent significantly with the best content of phenolic resin is 0.5 % or 1 %.
Mycobacterium tuberculosis Rv3651 is a triple sensor‐domain protein
Authors: Abendroth Jan , Frando Andrew , Phan Isabelle Q. , Staker Bart L. , Myler Peter J. , Edwards Thomas E. , Grundner Christoph 
Published: November 2017

AbstractThe genome of the human pathogen Mycobacterium tuberculosis (Mtb) encodes ∼4,400 proteins, but one third of them have unknown functions. We solved the crystal structure of Rv3651, a hypothetical protein with no discernible similarity to proteins with known function. Rv3651 has a three‐domain architecture that combines one cGMP‐specific phosphodiesterases, adenylyl cyclases and FhlA (GAF) domain and two Per‐ARNT‐Sim (PAS) domains. GAF and PAS domains are sensor domains that are typically linked to signaling effector molecules. Unlike these sensor‐effector proteins, Rv3651 is an unusual sensor domain‐only protein with highly divergent sequence. The structure suggests that Rv3651 integrates multiple different signals and serves as a scaffold to facilitate signal transfer.
How Effective is Plasmonic Enhancement of Colloidal Quantum Dots for Color‐Conversion Light‐Emitting Devices?
Authors: Park Hyun Chul , Isnaeni  , Gong Suhyun , Cho Yong‐Hoon 
Published: November 2017

AbstractEnhancing the fluorescence intensity of colloidal quantum dots (QDs) in case of color‐conversion type QD light‐emitting devices (LEDs) is very significant due to the large loss of QDs and their quantum yields during fabrication processes, such as patterning and spin‐coating, and can therefore improve cost‐effectiveness. Understanding the enhancement process is crucial for the design of metallic nanostructure substrates for enhancing the fluorescence of colloidal QDs. In this work, improved color conversion of colloidal green and red QDs coupled with aluminum (Al) and silver (Ag) nanodisk (ND) arrays designed by in‐depth systematic finite‐difference time domain simulations of excitation, spontaneous emission, and quantum efficiency enhancement is reported. Calculated results of the overall photoluminescence enhancement factor in the substrate of 500 × 500 µm2 size are 2.37‐fold and 2.82‐fold for Al ND‐green QD and Ag ND‐red QD structures, respectively. Experimental results are in good agreement, showing 2.26‐fold and 2.66‐fold enhancements for Al ND and Ag ND structures. Possible uses of plasmonics in cases such as white LED and total color conversion for possible display applications are discussed. The theoretical treatments and experiments shown in this work are a proof of principle for future studies of plasmonic enhancement of various light‐emitting materials.
(p, q)-webs of DIM representations, 5d $$ \mathcal{N}=1 $$ instanton partition functions and qq-characters
Authors: Bourgine J.-E. , Fukuda M. , Harada K. , Matsuo Y. , Zhu R.-D. 
Published: November 2017

AbstractInstanton partition functions of$$ \mathcal{N}=1 $$N=15d Super Yang-Mills reduced onS1can be engineered in type IIB string theory from the (p,q)-branes web diagram. To this diagram is superimposed a web of representations of the Ding-Iohara-Miki (DIM) algebra that acts on the partition function. In this correspondence, each segment is associated to a representation, and the (topological string) vertex is identified with the intertwiner operator constructed by Awata, Feigin and Shiraishi. We define a new intertwiner acting on the representation spaces of levels (1, n) ⊗ (0, m) → (1, n + m), thereby generalizing to higher rank m the original construction. It allows us to use a folded version of the usual (p,q)-web diagram, bringing great simplifications to actual computations. As a result, the characterization of Gaiotto states and vertical intertwiners, previously obtained by some of the authors, is uplifted to operator relations acting in the Fock space of horizontal representations. We further develop a method to build qq-characters of linear quivers based on the horizontal action of DIM elements. While fundamental qq-characters can be built using the coproduct, higher ones require the introduction of a (quantum) Weyl reflection acting on tensor products of DIM generators.