bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hospital-Acquired Methicillin-Resistant Staphylococcus aureus Bloodstream Infections in Québec: Impact of Guidelines
Authors: Li Lynne , Fortin Elise , Tremblay Claude , Ngenda-Muadi Muleka , Garenc Christophe , Moisan Danielle , Villeneuve Jasmin , Quach Caroline ,   for SPIN-BACC and SPIN-SARM
Published: June 2017

OBJECTIVEWe examined the impact of methicillin-resistant Staphylococcus aureus (MRSA) guidelines in Québec adult hospitals from January 1, 2006, to March 31, 2015, by examining the incidence rate reduction (IRR) in healthcare-associated MRSA bloodstream infections (HA-MRSA), using central-line associated bloodstream infections (CLABSIs) as a comparator.METHODSIn this study, we utilized a quasi-experimental design with Poisson segmented regression to model HA-MRSA and CLABSI incidence for successive 4-week surveillance segments, stratified by teaching status. We used 3 distinct periods with 2 break points (April 1, 2007, and January 3, 2010) corresponding to major MRSA guideline publications and updates.RESULTSOver the study period, HA-MRSA incidence decreased significantly in adult teaching facilities but not in nonteaching facilities. Prior to MRSA guideline publication (2006–2007), HA-MRSA incidence decrease was not significant (P=.89), while CLABSI incidence decreased by 4% per 4-week period (P=.05). After the publication of guidelines (2007–2009), HA-MRSA incidence decreased significantly by 1% (P=.04), while no significant decrease in CLABSI incidence was observed (P=.75). HA-MRSA and CLABSI decreases were both significant at 1% for 2010–2015 (P<.001 and P=.01, respectively). These decreases were gradual rather than sudden; break points were not significant. Teaching facilities drove these decreases.CONCLUSIONDuring the study period, HA-MRSA and CLABSI rates decreased significantly. In 2007–2009, the significant decrease in HA-MRSA rates with stable CLABSI rates suggests an impact from MRSA-specific guidelines. In 2010–2015, significant and equal IRRs for HA-MRSA and CLABSI may be due to the continuing impact of MRSA guidelines, to the impact of new interventions targeting device-associated infections in general by the 2010–2015 Action Plan, or to a combination of factors.Infect Control Hosp Epidemiol 2017;38:840–847
The effects of a post-exercise carbohydrate and protein supplement on repeat performance, serum chemistry, insulin and glucagon in competitive weight-pulling dogs
Authors: Frye Christopher W. , VanDeventer Gretchen M. , Dinallo Gina K. , Poplarski Jennifer A. , Mann Sabine , Pittman Ella , Zanghi Brian M. , Wakshlag Joseph J. 
Published: June 2017

AbstractThe physiological demands of weight-pulling dogs have yet to be investigated. Two groups of competitive weight-pulling dogs both underwent two identical pull series 3 h apart. The control group (n8) was compared with a group fed a rapidly digestible carbohydrate and protein supplement after the first pull series (n9). Blood was drawn before and after each pull series as well as at 15 and 30 min after the first pull series finished. Biochemistry values remained unremarkable throughout the study in both groups regardless of supplementation or exercise over time. Lactic acid showed mild significant increases post-exercise (2·1 (sd1·2) mmol/l) compared with baseline (1·4 (sd0·3) mmol/l;P = 0·03) after the initial pull series. When examining the effects of time there was a significant increase in insulin from baseline (median of 10·8 (range 6·8–17·4) μIU/ml) compared with 30 min after supplementation (17·0 (range 8·1–33·0) μIU/ml) and at 3 h after supplementation (19·2 (range 9·7–53·4) μIU/ml). In the treatment group there was also a time effect, with glucagon being elevated from baseline (median of 100 (range 79–115) pg/ml) compared with 30 min after supplementation (114 (range 90–183) pg/ml) and after the second pull series (131 (range 107–152) pg/ml). Evaluation of each dog's ability to pull the same or greater amount of weight on the second pull series revealed no significant differences. In conclusion, weight-pulling dogs have mild elevations in lactate reflecting little anaerobic metabolism compared with other canine sprinting athletes; hormonal changes associated with carbohydrate absorption are reflected within the treatment group, and supplementation had no effect on performance.
A higher Dietary Inflammatory Index score is associated with a higher risk of breast cancer among Chinese women: a case–control study
Authors: Huang Wu-Qing , Mo Xiong-Fei , Ye Yan-Bin , Shivappa Nitin , Lin Fang-Yu , Huang Jing , Hébert James R. , Yan Bo , Zhang Cai-Xia 
Published: June 2017

AbstractPrevious studies have investigated the association between dietary inflammatory potential and the development of cancer. For breast cancer the results have been equivocal. The present study aimed to investigate whether higher Dietary Inflammatory IndexTM (DII) scores were associated with increased risk of breast cancer among Chinese women. A total of 867 cases and 824 controls were recruited into the present case–control study from September 2011 to February 2016. DII scores were computed based on baseline dietary intake assessed by a validated 81-item FFQ. The OR and 95 % CI were assessed by multivariable logistic regression after adjusting for various potential confounders. DII scores in this study ranged from −5·87 (most anti-inflammatory score) to +5·71 (most proinflammatory score). A higher DII score was associated with a higher breast cancer risk (adjusted ORquartile 4 v. 1 2·28; 95 % CI 1·71, 3·03; adjusted ORcontinuous 1·40; 95 %CI 1·25, 1·39). In stratified analyses, positive associations also were observed except for underweight women or women with either oestrogen receptor+ or progesterone receptor+ status (but not both). Results from this study indicated that higher DII scores, corresponding to more proinflammatory diets, were positively associated with breast cancer risk among Chinese women.
Biological traits and the complex of parasitoids of the elm pest Orchestes steppensis (Coleoptera: Curculionidae) in Xinjiang, China
Authors: Li Q. , Triapitsyn S.V. , Wang C. , Zhong W. , Hu H.-Y. 
Published: June 2017

AbstractThe flee-weevil Orchestes steppensis Korotyaev (Coleoptera: Curculionidae) is a steppe eastern Palaearctic species, notable as a serious pest of elms (Ulmus spp., Ulmaceae), by feeding on the leaves (adults) or mining them heavily (larvae), especially of Ulmus pumila L. in Xinjiang, China. We have corrected the previous misidentifications of this weevil in China as O. alni (L.) or O. mutabilis Boheman and demonstrated that it is likely to be an invasive species in Xinjiang. Prior to this study, natural enemies of O. steppensis were unknown in Xinjiang. Resulting from field investigation and rearing in the laboratory during 2013–2016, seven parasitoid species were found to be primary and solitary, attacking larval and pupal stages of the host weevil. Pteromalus sp. 2 is the dominant species and also is the most competitive among the seven parasitoids, which could considered to be a perspective biological control agent of O. steppensis. Yet, the current control of this pest by the local natural enemies in Xinjiang is still currently inefficient, even though in 2016 parasitism was about 36% on U. pumila in Urumqi, so the potential for a classical biological control program against it needs to be further investigated, including an assessment of its parasitoids and other natural enemies in the native range of O. steppensis. The presented information on the natural enemies of this weevil can be also important for a potential classical biological control program against it in North America (Canada and USA), where it is a highly damaging and rapidly spreading invasive species.
TO WHAT EXTENT DO COUPLES’ PRE-MARITAL COMMUNICATIONS AFFECT THEIR POST-MARITAL FERTILITY BEHAVIOUR IN INDIA?
Authors: Chatterjee Sayantani , Kastor Anshul 
Published: June 2017

SummaryReproduction in India is mainly confined to within marriage. The fertility preferences of spouses will not necessarily be the same, but discussion between couples creates scope for understanding between spouses after marriage. Knowing each other’s opinions facilitates decision-making on sensitive matters such as contraception use and desired family size. This study used data from the India Human Development Survey-II (2011–12), and was based on a sample of 31,276 currently married women. The aim was to understand the role of pre-marital communication, studied through the choosing of husbands, mutual communication before marriage and duration of time spouses knew each other before marriage on the fertility preferences of couples post-marriage. These preferences included contraception use, who has most say on the number of children and the gap between desired and actual number of offspring. The results showed that wives who knew their husbands or who had any kind of communication with them before marriage had a greater chance of being involved in fertility decisions. However, most fertility decisions were found to be male-driven. Wives who knew their husbands for more than a month before marriage took more decisions on number of children (27%) than those who only knew their husbands from the day of their wedding (20%). Wives were less likely to have more children/sons/daughters than desired if they had some communication with their husbands before marriage. A better understanding of fertility preferences between spouses might help to curb unwanted births through delaying or limiting births by contraception use. Families in India could encourage couples to interact before marriage so they can make collective decisions on contraception use and/or the number of children they have.
Stress sensitivity in paranoia: poor-me paranoia protects against the unpleasant effects of social stress
Authors: Udachina A. , Bentall R. P. , Varese F. , Rowse G. 
Published: June 2017

BackgroundThe attributional theory of paranoia suggests that paranoid beliefs may protect individuals from low self-esteem and distress (Bentall et al. 2001). The current study tested this theory by investigating a hypothesis that paranoid beliefs in combination with low perceived deservedness of persecution (poor-me beliefs) confer protection against the distress caused by social but not activity related stress.MethodsParanoid symptoms, perceived deservedness of persecution, self-esteem, mood, and stress levels of individuals diagnosed with schizophrenia spectrum disorders (N = 91) and healthy controls (N = 52) were assessed in the context of daily life using the experience sampling method.ResultsIndividuals holding poor-me beliefs (poor-me individuals) showed blunted sensitivity to social but not activity stress. In contrast, individuals holding paranoid beliefs in combination with high perceived deservedness of persecution (bad-me individuals) showed heightened sensitivity to social stress. No consistent differences in reactions to activity stress emerged. Although both poor-me and bad-me individuals reported low self-esteem, this disturbance was particularly characteristic of bad-me individuals.ConclusionsThe results suggest that poor-me paranoid beliefs may protect individuals against the distress associated with unpleasant social situations. The specificity of reactions to social stress is discussed in the context of wider literature. Future directions for research are suggested.
Practising gender, queering theory
Authors: Wilcox Lauren 
Published: June 2017

AbstractThe development of a ‘practice turn’ in International Relations promises to reconstitute IR theory around the study of embodied practices. Despite occasional references to Judith Butler’s work, the contributions of feminist and queer theory are under recognised in existing work. In this piece I note the distinctive approach to gender as a practice represented by Butler and other feminist/queer theorists for its emphasis on intelligibility and failure, particularly the importance on ‘competently’ practising gender in order to established as an intelligible subject. Given the centrality of ‘competency’ in ‘practice turn’ literature, theorising practice from the perspective of ‘gender failures’ sheds light on the embedded exclusions within this literature. To demonstrate the stakes of this critique, I discuss airport security practices, a growing area of interest to IR scholars, in terms of the experiences of trans- and gender non-conforming people. I argue that such practices ultimately complicate success/failure binaries. I conclude by considering the political stakes of practising theory in IR and how competency in theory is similarly marked by the exclusion of feminist/queer work.
SHAPING QUALITY THROUGH VISION, STRUCTURE, AND MONITORING OF PERFORMANCE AND QUALITY INDICATORS: IMPACT STORY FROM THE QUEBEC TRAUMA NETWORK
Authors: Truchon Catherine , Moore Lynne , Belcaid Amina , Clément Julien , Trudelle Nathalie , Ulysse Marie-Andrée , Grolleau Benoît , Clusiau Jacinthe , Lévesque Danielle , de Guise Michèle 
Published: June 2017

Objectives: The Quebec Trauma Care Continuum (TCC) was initiated in 1991 with the objective of providing accessible, continuous, efficient, and high quality services for all injury cases in the province.Methods: The TCC design relied on three key components: (i) the designation of a network of acute care and rehabilitation facilities with specific mandates and responsibilities; (ii) the elaboration of transfer protocols, standing agreements, and governing structures to ensure fluid and optimal patient flow; and (iii) the close monitoring of several indicators to facilitate the continuous evaluation and improvement of the network.Results: Between 1992 and 2002, in-hospital mortality following major trauma decreased from 51.8 percent to 8.6 percent, followed by an additional 24 percent drop between 1999 and 2012. We also observed a 16 percent decrease in average LOS but no change in the incidence of complications or unplanned readmissions. These changes translate into 186 lives saved per year and cost savings, due to shorter LOS, of 6.3 million CD$ per year. The risk-adjusted incidence of in-hospital mortality following major injury between 2006 and 2012 (7 percent) was the lowest of all Canadian provinces.Conclusions: Strategic transformation of a network's structure and processes, supported by continuous monitoring of validated quality indicators, can lead to significant and sustainable improvements in clinical outcomes. It is hoped that the Quebec trauma story will inspire other jurisdictions and other healthcare sectors.
DEVELOPMENTS IN VALUE FRAMEWORKS TO INFORM THE ALLOCATION OF HEALTHCARE RESOURCES
Authors: Oortwijn Wija , Sampietro-Colom Laura , Habens Fay 
Published: June 2017

Background:In recent years, there has been a surge in the development of frameworks to assess the value of different types of health technologies to inform healthcare resource allocation. The reasons for, and the potential of, these value frameworks were discussed during the 2017 Health Technology Assessment International (HTAi) Policy Forum Meeting.Methods:This study reflects the discussion, drawing on presentations from invited experts and Policy Forum members, as well as a background paper.Results:The reasons given for a proliferation of value frameworks included: rising healthcare costs; more complex health technology; perceived disconnect between price and value in some cases; changes in societal values; the need for inclusion of additional considerations, such as ethical issues; and greater empowerment of clinicians and patients in defining and using value frameworks. Many Policy Forum participants recommended learning from existing frameworks. Furthermore, there was a desire to agree on the core components of value frameworks, defining the additional value elements as necessary and considering how they might be measured and used in practice. Furthermore, adherence to the principles of transparency, predictability, broad stakeholder involvement, and accountability were widely supported, along with being forward looking, explicit, and consistent across decisions.Conclusions:Value frameworks continue to evolve with significant implications for global incentives for innovation and access to health technologies. There is a role for the HTA community to address some of the key areas discussed during the meeting, such as defining the core components for assessing the value of a health technology.
Compliance with Clostridium difficile treatment guidelines: effect on patient outcomes
Authors: CROWELL K. T. , JULIAN K. G. , KATZMAN M. , BERG A. S. , TINSLEY A. , WILLIAMS E. D. , KOLTUN W. A. , MESSARIS E. 
Published: June 2017

SUMMARYGuidelines for the severity classification and treatment of Clostridium difficile infection (CDI) were published by Infectious Diseases Society of America (IDSA)/Society for Healthcare Epidemiology of America (SHEA) in 2010; however, compliance and efficacy of these guidelines has not been widely investigated. This present study assessed compliance with guidelines and its effect on CDI patient outcomes as compared with before these recommendations. A retrospective study included all adult inpatients with an initial episode of CDI treated in a single academic center from January 2009 to August 2014. Patients after guideline publication were compared with patients treated in 2009–2010. Demographic, clinical, and laboratory data were collected to stratify for disease severity. Outcome measures included compliance with guidelines, mortality, length of stay (LOS), and surgical intervention for CDI. A total of 1021 patients with CDI were included. Based upon the 2010 guidelines, 42 (28·8%) of 146 patients treated in 2009 would have been considered undertreated, and treatment progressively improved over time, as inadequate treatment decreased to 10·0% (15/148 patients) in 2014 (P = 0·0005). Overall, patient outcomes with guideline-adherent treatment decreased CDI attributable mortality twofold (P = 0·006) and CDI-related LOS by 1·9 days (P = 0·0009) when compared with undertreated patients. Compliance with IDSA/SHEA guidelines was associated with a decreased risk of mortality and LOS in hospitalized patients with CDI.
Differential prevalence and correlates of whole blood Epstein–Barr virus DNA between HIV-positive and HIV-negative men who have sex with men in Shanghai, China
Authors: PAN R. , LIU X. , ZHOU S. , NING Z. , ZHENG H. , GAO M. , DING Y. , YAO W. , LIAO X. , HE N. 
Published: June 2017

SUMMARYThis cross-sectional study aimed to examine and compare prevalence and correlates of whole blood Epstein–Barr virus (EBV) DNA between HIV-positive and HIV-negative men who have sex with men (MSM). Five hundred and four HIV-positive MSM and 504 age-matched HIV-negative MSM were recruited from an HIV counseling and testing clinic in Shanghai, China from November 2014 to November 2015 and were administered with a face-to-face questionnaire interview. Whole blood EBV DNA was tested by nested polymerase chain reaction assays on EBNA-1, EBNA-2, and LMP-1 genes. The prevalence of whole blood EBV DNA was 56·0% (95% CI 51·7–60·3%) among HIV-positive MSM and 26·0% (95% CI 22·4–30·0%) among HIV-negative MSM. Whole blood EBV DNA positivity was significantly associated with HIV infection (adjusted odds ratio (aOR) 3·43, 95% CI 2·58–4·57) and frequent intake of pickled, smoked, or salty food (aOR 1·71, 95% CI 1·02–2·86) in the whole sample, and with <200 cells/μl CD4 cell counts (aOR 1·79, 95% CI 1·05–3·05) and pickled, smoked, or salty food intake (aOR 3·14, 95% CI 1·39–7·08) in HIV-positive group. HIV-infected MSM are at higher risk of active EBV replication than HIV-uninfected MSM, underscoring needs of surveillance and research on EBV-related carcinogenesis in this population.
Using automated sanding to homogeneously break seed dormancy in black locust (Robinia pseudoacaciaL., Fabaceae)
Authors: Bouteiller Xavier P. , Porté Annabel J. , Mariette Stéphanie , Monty Arnaud 
Published: June 2017

AbstractPhysical dormancy ofRobinia pseudoacaciaseeds makes it a challenge for scientists and forest managers to obtain a homogeneous germination for larger seed samples. Water imbibition of the seeds can be achieved through manual piercing of the seed coat, but this method remains time consuming and heterogeneous. We tested several ecologically friendly methods to break seed dormancy, including manual pin puncture, water soaking, oven dry-heating (two temperatures) and sanding. Sanding was performed using an automatic grinder to control shaking duration (three durations) and get a homogeneous scraping of the coat. All methods, except dry-heating, resulted in successful dormancy breaking; water soaking was the least efficient method, attaining 57% germination. Sanding proved to be as efficient as puncturing (97%) but long duration sanding (10 or 15 min) could damage cotyledons, which would impede further development of the plant. Short-time sanding (5 min) proved to be the best method to reach high total germination and healthy (undamaged cotyledon) seedlings, and was successfully applied to 500 seeds. The reference puncture method and the automatic sanding were also tested on seeds of nine Fabaceae species and proved to be efficient for some species. Automated sanding can thus be used as a standard to break physical dormancy of black locust or other Fabaceae seeds to allow further comparative studies of plant populations or genotypes.
Perception v. actual intakes of junk food and sugar-sweetened beverages in Australian young adults: assessed using the mobile food record
Authors: Harray Amelia J , Boushey Carol J , Pollard Christina M , Panizza Chloe E , Delp Edward J , Dhaliwal Satvinder S , Kerr Deborah A 
Published: June 2017

AbstractObjectiveTo determine perception v. actual intakes of energy-dense nutrient-poor ‘junk food’ (JF) and sugar-sweetened beverages (SSB) in young adults, using the mobile food record (mFR).DesignBefore-and-after eating images using a 4 d mFR were assessed for standardised 600 kJ (143 kcal) servings of JF and SSB (excluding diet drinks). Participants reported their concern about the health aspects of their diet, perceptions and intentions regarding JF and SSB.SettingPerth, Western Australia.SubjectsAdults (n 246) aged 18–30 years.ResultsThe mean (sd) intake of JF+SSB was 3·7 (2·0) servings/d. Women thinking about drinking less SSB consumed more SSB servings/d (1·5 (1·2)) than men (0·7 (0·5); P<0·05) who were thinking about drinking less. Men not thinking about cutting down JF consumed more servings/d (4·6 (2·4)) than women (2·5 (0·7); P<0·01) who were not thinking about cutting down. Those who paid a lot of attention to the health aspects of their diet consumed less JF+SSB than those who took only a bit of notice (P<0·001), were not really thinking much about it (P<0·001) or who didn’t think at all about the health aspects of food (P<0·01).ConclusionsPerceptions and attitudes regarding JF and SSB were associated with level of consumption. Those not thinking about cutting down their intake of these foods represent an important target group as they consume more than their peers. Further research is needed to identify how amenable young adults are to changing their intake, particularly given the lack of attention paid to the health aspects of their diet.