bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Internal Anterior Chamber Diameter Measured with Ultrabiomicroscopy with White-to-White Distance Measured Using Digital Photography in Aphakic Eyes
Authors: Wilczynski Michal , Bartela Joanna , Synder Aleksandra , Omulecki Wojciech 
Published: January 2018

Purpose Measuring the anterior chamber diameter (AC) is important both for diagnostics and before ocular surgery. In clinical practice, horizontal AC diameter is usually estimated on the basis of measurements of corneal diameter (so-called white-to-white [WTW] distance). The usual method for selecting an appropriate size for an AC lens is to add 1 mm to WTW measurement. The purpose of this study was to compare AC diameter measured using ultrasound biomicroscopy (UBM) with WTW distance measured using digital photography in aphakic eyes. Methods The data were gathered prospectively from a nonrandomized consecutive series of aphakic patients. The examined group consisted of 23 eyes of 23 adult patients, mean age 71.17 years. WTW diameter was measured in the 3 o'clock and 9 o'clock meridian on a digital photograph. Internal horizontal AC diameter measurements were performed in the 3 o'clock and 9 o'clock meridian with the Sonomed Ultrabiomicroscopy device with a 50-MHz probe. Results Mean horizontal WTW diameter measured using digital photographs was 11.65±0.38 mm and mean horizontal internal AC diameter measured using UBM was 13.53±0.83 mm. A significant difference in mean WTW diameter measured using digital photography and UBM was found (Mann-Whitney U test, p<0.05). There was a significant correlation between these values (Spearman=0.70, p<0.001). Conclusions In order to obtain good and precise measurements of internal AC diameter, a method of direct visualization of the intraocular structures should be used. Despite the limits of a small case series, our results support the use of UBM technique for preoperative evaluation of the internal AC diameter and AC intraocular lens sizing in aphakic eyes.
Bilateral Implantation of the Acri.LISA Bifocal Intraocular Lens in Myopic Eyes
Authors: Fernández-Vega Luis , Madrid-Costa David , Alfonso José F. , Poo-López Arancha , Montés-Micó Robert 
Published: January 2018

Purpose To asses visual quality after bilateral implantation of the Acri.LISA 366D intraocular lens (IOL) (Carl Zeiss Meditec) in patients with high and low–moderate myopia. Methods A total of 304 eyes of 152 patients had bilateral implantation of the Acri.LISA 366D IOL. The patients were divided into 2 groups: low–moderate myopia (IOL power from 15 to 20.5 D) and high myopia (IOL power from 0 to 14.5 D). Monocular and binocular best-corrected distance visual acuity (BCVA) and best distance-corrected near visual acuity (BCNVA), binocular best distance-corrected intermediate visual acuity (BCIVA), and distance contrast sensitivity (OS) under photopic (85 cd/m2) and mesopic (5 cd/m2) conditions were determined. Results At the 6-month postoperative visit, there were no statistically significant differences in monocular and binocular BCVA (p=0.13 and p=0.22, respectively). Monocular and binocular BCNVA was comparable between the groups (p=0.26 and p=0.09, respectively). The mean binocular BCIVA changed significantly as a function of the distance of the test (p<0.01) in both groups, and there were no statistically significant differences between groups at any distance. Monocular and binocular CS under photopic and mesopic conditions was similar between both groups (p>0.01). Conclusions Bilateral implantation of the Acri.LISA 366D in high myopic eyes provides a satisfactory full range of vision comparable to that obtained in low–moderate myopic eyes.
Visual Acuity and Contrast Sensitivity Function after Accommodative and Multifocal Intraocular Lens Implantation
Authors: Mesci Cem , Erbil Hasan , Özdöker Levent , Karakurt Yücel , Bilge Ayse Dolar 
Published: January 2018

Purpose To evaluate visual acuities and contrast sensitivities (CS) after accommodative, refractive, and diffractive multifocal intraocular lens (IOL) implantations. Methods After cataract extractions, in 20 eyes accommodative IOL (group 1), in 30 eyes refractive IOL (group 2), and in 20 eyes diffractive multifocal IOL (group 3) implantations were performed. CS were measured with the stereo optical functional acuity contrast test. Uncorrected distance (UCDVA) and distance corrected near visual acuities (DCNVA) and refractive values were determined. Results The mean UCDVA (0.99±0.03) and DCNVA (0.98±0.04) of group 3 were significantly better than the other IOL groups. The mean DCNVA of group 2 (0.71±0.14) was significantly better than group 1 (0.5±0.08). One month after the operations CS, values of group 2 were significantly lower than the 2 other IOL groups. Photopic CS values of group 1 at 12 and 18 cycles per degree (cpd) were significantly higher than group 3. Three months after the operations, CS values of group 1 and 3 were significantly higher than that of group 2 at 3, 6, 12, and 18 cpd and in all spatial frequencies respectively. There was no difference between groups 1 and 3 with respect to photopic CS values. Mesopic CS values of group 3 were significantly higher than that of group 1 at 1.5, 3, and 6 cpd. At the 6th and 12th month, CS values of group 3 were similar or better compared to the values of the 3rd month. Conclusions The diffractive multifocal IOL resulted in more favorable visual acuities and higher CS values than accommodative and refractive multifocal IOL.
Why is Cataract Surgery Canceled? A Retrospective Evaluation
Authors: Bamashmus Mahfouth , Haider Talal , Al-Kershy Reem 
Published: January 2018

Purpose We performed this retrospective study to evaluate and report the reasons for cancellation of elective cataract surgeries in our tertiary care hospital, Kuwait University Hospital, from January 2001 until December 2003. Proportion of elective cataract surgeries canceled on the day of surgery was obtained from the operating theater list and reasons for cancellations were recorded. Methods The selected patients for the surgery had gone through preoperative investigations including complete blood count, random blood sugar, coagulation profile, urea and electrolytes, viral serology (hepatitis B, hepatitis C, and human immunodeficiency virus), intraocular lens calculation, and medical condition assessed for chronic diseases. Results A total of 1952 patients were scheduled for elective cataract surgery. A total of 234 cases (12%) were canceled due to different reasons on the day of surgery. Main reasons for cancellation were poor control of systemic hypertension (77), canceled by patient (46), improper control of diabetes (20), patients did not bring the intraocular lens (18), chest infection or influenza in children (17), local eye infection (13), cardiac problems (11), high intraocular pressure after local anesthesia (8), and uncooperative patients (7). Conclusions Postponing elective cataract surgery for patients scheduled for surgery is a stressful situation for the patients and their relatives. Most reasons (80%) for canceling the surgery were avoidable and efforts to reduce the number of postponed cases should be increased. Medical fitness should be done properly to avoid unexpected rise in blood pressure and blood sugar on the day of surgery.
Toxic Anterior Segment Syndrome after Uncomplicated Cataract Surgery
Authors: Ozcelik N. Demet , Eltutar Kadir , Bilgin Burak 
Published: January 2018

Purpose To evaluate the anterior segment examination findings and the response to medical therapy of patients who had toxic anterior segment syndrome (TASS) after uncomplicated cataract surgery. Methods Fourteen eyes of 14 patients were enrolled in the study. Visual acuity, biomicroscopic anterior segment examination, intraocular pressure measurement, and fundus examination were performed to assess TASS occurring during postoperative 12–48 hours after uncomplicated phaco surgery. The visual impairment, corneal edema, tyndallization, fibrin formation, hypopyon, vitritis, and response to steroid therapy were evaluated prospectively. Results After topical steroid therapy lasting for 1 week, visual acuity improved in 11 eyes. No significant visual improvement occurred in 3 eyes. Significant corneal edema was found in 4 and mild corneal edema was observed in the other 10 eyes. Fibrin reaction occurred in 5 and tyndallization in various degrees was positive in all eyes. There was a 1-mm hypopyon in 1 patient. There was no sign of vitritis and steroid therapy was effective in all of the patients. In addition to topical treatment with steroid and antibiotic drops; systemic and subconjunctival steroids were used in 3 patients who had fibrin formation and in one patient who had hypopyon. Conclusions After uncomplicated cataract surgery, toxic anterior segment may occur in the early postoperative period, which is treated successfully with steroids. More studies are needed to understand the multifactorial risk factors affecting the etiopathogenesis of this syndrome.
Intravitreal Phacoemulsification with Pars Plana Vitrectomy for Management of Posteriorly Dislocated Nucleus or Lens Fragments
Authors: Soliman-Mahdy Mohamed Abdel-Monem E. , Zakaria Eid Mohamed , Shalaby Khalid Abdel-Gelil , Hegazy Hasan Mohamed 
Published: January 2018

Purpose Dislocation of crystalline lens nucleus/fragments into the vitreous cavity during phacoemulsification is a potentially serious, sight-threatening, uncommon complication of cataract surgery. It is associated with significant intraocular inflammation and can lead to poor visual outcome. The current study assesses the outcome of immediate intravitreal phacoemulsification with pars plana vitrectomy in management of posteriorly dislocated nucleus/lens fragments. Methods In this retrospective case series, records of 23 patients who underwent immediate pars plana vitrectomy and intravitreal phacoemulsification for removal of dislocated nucleus/lens fragments at the same sitting of phacoemulsification were reviewed. Data including patients’ preoperative and postoperative vision and intraoperative and postoperative complications were recorded. Results The mean follow-up period was 16.5 months (range, 5–31 months). Preoperative visual acuity ranged from 0.05 to 0.5. The final postoperative visual acuity ranged between HM and 1.0. Fifty-two percent of eyes (12 eyes) had a final postoperative visual acuity of 0.5 or better. Complications included 2 cases of cystoid macular edema and 2 cases of retinal detachment. Conclusions Immediate vitrectomy and intravitreal phacoemulsification is a surgical option in the management of posteriorly dislocated nucleus/lens fragments without much risk of retinal damage. It is relatively safe and most patients achieved a good visual outcome. The risk of postoperative complications including uveitis, secondary glaucoma, and cystoid macular edema could be minimized.
Efficacy of 2% Ibopamine on the Dilation of Patients with Pseudoexfoliation Syndrome
Authors: Luca Scuderi Gian , Regine Federico , Perdicchi Andrea , Turtoro Angela , Teresa Contestabile Maria 
Published: January 2018

Purpose To compare the mydriatic effects of 2% ibopamine and collyrium containing 10% phenylephrine + 0.5% tropicamide and to study the associated drug in patients with ocular pseudoexfoliation (PEX) syndrome. Methods This was a prospective, comparative, interventional clinical study. The study group consisted of 20 patients with ocular PEX syndrome. Intervention procedures included administration of 10% phenylephrine-0.5% tropicamide versus 2% ibopamine versus 2% ibopamine followed by the combination drug. Main outcome measurement was mydriatic efficacy measured in terms of mean pupil diameter. Adverse effects on intraocular pressure (IOP) were measured with a Goldmann applanation tonometer. Mean premedication pupil diameters in all patients were less than 3.5 mm. Results Instillation of 10% phenylephrine-0.5% tropicamide caused significantly greater mydriasis than 2% ibopamine (pupil diameters: 6.17 mm, SD=1.14 versus 5.33 mm, SD=1.34; p<0.001). Combined use of both collyria significantly increased mydriasis (7.19 mm; SD=0.69) compared with that induced by either of the products alone (p<0.001). Inadequate mydriasis (pupil diameters < 5.5 mm) was observed in 2 patients after administration of 10% phenylephrine-0.5% tropicamide and in 10 following instillation of 2% ibopamine, but the addition of 10% phenylephrine-0.5% tropicamide to ibopamine-treated eyes resulted in adequate dilation in all cases. IOP increases of 4 mmHg over baseline values were observed in 12 (60%) patients after 2% ibopamine. Conclusions In patients with ocular PEX, instillation of 2% ibopamine exerts a significant additive effect on mydriasis induced with 10% phenylephrine-0.5% tropicamide with only minimal increases in IOP
Progressive Changes in the Retinal Nerve Fiber Layer in Patients with Multiple Sclerosis
Authors: García-Martín Elena , Pueyo Victoria , Martin Jesus , Almarcegui Carmen , Ara Jose R. , Dolz Isabel , Honrubia Francisco M. , Fernández Francisco J. 
Published: January 2018

Purpose To quantify changes in the retinal nerve fiber layer (RNFL) of patients with multiple sclerosis (MS) over a 1-year time period and to compare the ability of noninvasive diagnostic imaging devices and visual evoked potentials (VEP) to detect axonal loss in these patients. Methods Eighty-one patients with MS underwent a complete ophthalmic examination that included assessment of visual acuity and color vision, refractive evaluation, visual field examination, optical coherence tomography (OCT), scanning laser polarimetry (GDx), and measurement of VEP. All the patients were re-evaluated after a period of 12 months in order to quantify any change in the RNFL. Only one randomly chosen eye from each patient was included in the study. Results Statistically significant differences between the 2 examinations were recorded for the overall mean and inferior RNFL thickness and the macular volume, as assessed by OCT, as well as for the temporal-superior-nasal-inferior-temporal average standard deviation provided by GDx. The greatest differences were obtained for the mean RNFL thickness (90.46 μm vs 85.96 μm). Changes in the optic nerve were detected by structural measurements but not by functional assessments. Conclusions Axonal loss in the optic nerve of patients with MS is greater than that expected in healthy subjects, regardless of the presence of a previous optic neuritis.
Course of Intraocular Pressure after Intravitreal Injection of 0.05 mL Ranibizumab (Lucentis®)
Authors: Sharei Vahid , Höhn Fabian , Köhler Thomas , Hattenbach Lars-Olof , Mirshahi Alireza 
Published: January 2018

Purpose This prospective study examines the changes in short-term intraocular pressure (IOP) in patients with wet age-related macular degeneration (AMD) receiving intravitreal injections of 0.05 mL ranibizumab (Lucentis®) in a supine position. Methods A total of 45 eyes (45 patients, 16 M, 29 F, mean age: 78 y) received intravitreal ranibizumab injections for treatment of wet AMD (0.05 mL = 0.5 mg). The IOP was measured by Schiötz tonometry immediately preoperatively and postoperatively, and also after 3 and 10 minutes in a supine position. No history of glaucoma was present. Results The mean preoperative IOP was 22.4±5.5 mmHg in supine position. Immediately after the injection, IOP increased to 47.9±15.1 (range 23–82, p<0.001), with 32 eyes (71.1%) >40 and 19 eyes (42.2%) >50 mmHg. The mean difference between preoperative IOP and immediately after the injection was +25.5±13.6 mmHg. IOP decreased spontaneously by the first 3 minutes after operation by 12.6±6.0 mmHg and after 10 minutes by 21±9.4 mmHg. The mean difference between preoperative IOP and 10 minutes postoperatively was +4.6±7.0 mmHg (range: −9.3 to +25.9 mmHg, p<0.001). Eyes without a subconjunctival reflux had a higher increase in IOP than eyes with any reflux (p<0.001). Conclusions IOP increased significantly in a considerable number of patients after intravitreal ranibizumab injections. A rapid and spontaneous decline was observed in the majority of cases. If there is no subconjunctival reflux after the injection, the increase in IOP is higher than in eyes with any back-flow under the conjunctiva.
Which Choroidal Melanoma Should be Treated with Primary Transpupillary Thermotherapy? Our Experience from 78 Patients
Authors: Yarovoy Andrey A. , Magaramov Dzhavid A. , Bulgakova Evgeniya S. 
Published: January 2018

Purpose To report the outcomes of primary transpupillary thermotherapy (TTT) for choroidal melanomas. Methods A total of 78 patients were treated with TTT. Tumor thickness was up to 3.6 mm (mean 2.05 mm), follow-up 2.5–108 months (mean, 32.8 months). The main outcome measures were local control, enucleations, tumor recurrences, complications, and visual acuity. The predictors of treatment failures were analyzed. Results A total of 51 tumors regressed completely, and 20 incompletely. Out of 7 patients without response, 2 had enucleation, and 5 had Ru-106 irradiation. Recurrences after primary response were observed in 10 patients in 7–54 months (mean 23.4), 8 of them after incomplete regression. Six recurrences were successfully treated with additional TTT, and 4 with brachytherapy There were no metastases or deaths. Logistic regression showed the main predictive factors for TTT failure to be tumor height (OR=6.85; 95% 01=1.2–38.1; p=0.02), basal diameter (OR=22.85; 95% 01=3.6–144.7; p=0.0003), amelanotic pigmentation (for primary failure, OR=9.18; 95% Cl=1.7–49.2; p=0.008), high maximum systolic velocity (for primary failure, OR=13.6; 95% 01=2.3–81.7; p=0.003), subretinal fluid (OR=11.04; 95% 01=1.2–100.4; p=0.03), and incomplete regression (OR=30.62; 95% 01=6.0–156.4; p=0.00001). Receiver operating characteristic analysis showed the following cutoff levels: for tumor height 3.0 mm, for basal diameter 10.2 mm, for maximum systolic velocity 11.7 cm/s. Kaplan-Meier analysis of negative results was fulfilled in all treated patients and in patients without negative predictors. Mean visual acuity before TTT was 0.65, and after treatment 0.58. A total of 23% of patients had increased visual acuity, 42% had decreased acuity, and there was no change in 35%. Conclusions TTT is an investigative treatment for choroidal melanomas. TTT needs careful selection of patients, based on consideration of predictive factors and functional perspectives.
Local Resection versus Combined Local Resection and Plaque Radiotherapy in the Treatment of Choroidal Melanoma
Authors: Querques Giuseppe , Bux Anna V. , Iaculli Chstiana , Delle Noci Nicola 
Published: January 2018

Purpose To evaluate the outcome of local resection versus combined local resection and plaque radiotherapy in the treatment of choroidal melanoma. Methods We retrospectively analyzed the records of 60 patients (60 eyes) managed by local resection (group 1, 30 patients, external or internal local resection) or combined local resection and plaque radiotherapy (group 2, 30 patients, both Ruthenium-106 or Cobalt-60), among the 364 melanomas treated at our Department of Ophthalmology, between January 1980 and December 2006. Main outcomes measures were postsurgical complications, visual acuity, local recurrence, reasons for enucleation, and development of metastasis. Results The 2 groups of patients were considered sufficiently homogeneous as regards location, cell type, and age. Mean follow-up was 7 years. The median largest basal tumor diameter was 9.8 mm and 10.1, and the median tumor thickness was 7.9 mm and 8, respectively, in groups 1 and 2. No statistically significant differences resulted between group 1 and group 2 as regards postsurgical complications (vitreous hemorrhage, retinal detachment, maculopathy cataract, and optic neuropathy) (p>0.05), visual acuity (p>0.05), local recurrence (p>0.05), reasons for enucleation (p>0.05), or development of metastasis (p>0.05). Conclusions NO adjunctive benefits from the combined local resection and plaque radiotherapy can be ruled out from our study.
Natural Killer/T-Cell Lymphoma of Nasal Type with Intraocular Involvement: Case Report
Authors: Lee Eun Ji , Wan Kim Tae , Won Heo Jang , Gon Yu Hyeong , Chung Hum 
Published: January 2018

Purpose To report an unusual presentation of disseminated, intraocular, extranodal natural killer/T-cell lymphoma, nasal type (NK/T-cell lymphoma), originating from nasal NK/T-cell lymphoma. Methods Case report. Results A 63-year-old woman who had been treated with systemic chemotherapy and radiotherapy for NK/T-cell lymphoma in the nasal cavity presented with vitreous haze of the right eye. Despite anti-inflammatory therapy, the right eye showed poor clinical response and received diagnostic vitrectomy. The vitreous opacity resembled a thin sheet, with no sign of subretinal infiltrate or vascular sheathing. The vitreous specimen contained many large, pleomorphic lymphoma cells. The malignant cells were positive for CD3, CD8, and granzyme B. Systemic workups showed no involvement of other organs. A diagnosis of T-cell lymphoma in the vitreous was made; the tumor likely originated from nasal NK/T-cell lymphoma. The patient was treated with intrathecal chemotherapy and intravitreal methotrexate injection. The eye was clinically clear of malignant cells after the injections. Conclusions Vitreous infiltration without uveoretinal involvement can be an unusual manifestation of intraocular NK/T-cell lymphoma. Clinician awareness of possible ocular involvement may assist in the diagnosis of disseminated NK/T-cell lymphoma.
Necrotizing Retinopathy Simulating Acute Retinal Necrosis Causing Rhegmatogenous Retinal Detachment in Sarcoidosis: A Case Report
Authors: Shenoy Radha , AI Burwani Badar 
Published: January 2018

Purpose To report on the occurrence of necrotizing type of retinopathy resulting in rhegmatogenous retinal detachment in a patient with asymptomatic sarcoidosis. Methods A 38-year-old healthy man presented with poor vision of 0.1 in his left eye of 3 days duration and was found to have panuveitis with occlusive periarteritis and inflammatory infiltrates in the peripheral retina. He was diagnosed with asymptomatic systemic sarcoidosis based on blood investigations and total body gallium scan and was treated with pulse methylprednisolone followed by oral steroids. Results Anterior uveitis, vitritis, and retinal infiltrates resolved with pulse methylprednisolone therapy, and there was complete visual recovery. However, deterioration occurred later with development of rhegmatogenous retinal detachment. Conclusions Necrotizing retinopathies simulating acute retinal necrosis have not been reported before in patients with sarcoidosis.
Unilateral Optic Atrophy Preceding Coats Disease in a Girl with Parry-Romberg Syndrome
Authors: Nasser Orwa , Greiner Kathrin , Amer Radgonde 
Published: January 2018

Purpose Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunction, Horner syndrome, reduced corneal sensitivity, band keratopathy, episcleritis, uveitis, neuroretinitis, and retinal vasculitis. Methods Descriptive case report. Results We report on the development of unilateral optic atrophy followed by ipsilateral Coats disease (CD) in a girl with PRS. Visual outcome was limited owing to the development of massive subretinal exudation and shallow retinal detachment in the posterior pole and inferior retina. Conclusions Optic atrophy was not previously described in association with PRS. We describe the development of unilateral optic atrophy with subsequent CD, 5 years later, in a girl with PRS.