bluuebunny/crossref_metadata_2025_split huggingface dataset:
Husserl's Analogical Axiological Reason: A Phenomenology of Wish Feeling Fulfillment
Authors: Byrne Thomas 
Published: October 2024

AbstractThe most contentious tenet of Husserl's phenomenology of feelings is his conclusion that there is an analogy between axiological reason and theoretical reason. Simply, Husserl asserts that the axiological validation of feelings is analogical to the theoretical validation of judgments. While the scholarship has debated the merits of Husserl's analogy over the last 120 years, this paper presents a new accurate interpretation, because it is the first to highlight how Husserl develops this analogy by most often comparing the fulfillment of judgments to the fulfillment of wish feeling intentions. Specifically, I examine how Husserl analogizes wish fulfillment to theoretical fulfillment at different times; in the 1901 Logical Investigations, in his 1908 Lectures on Ethics, and in 1910 manuscripts from Studien zur Struktur des Bewusstseins. In light of this original interpretation, I conclude by arguing – contra popular readings – that Husserl does not over‐intellectualize feelings and their validation.
Fungal endometritis associated with embryonic loss in a maiden mare
Authors: Gunn A. , Clark B. , Stephen C. , Simpson E. 
Published: October 2024

SummaryFungal endometritis and placentitis have been reported as a rare but important cause of infertility in the mare. There are no reported clinical cases of fungal endometritis causing embryonic loss in the mare. This case report aims to highlight the potential of fungal endometritis as an aetiological agent in embryonic loss in the mare; an incidental diagnosis of a case of fungal endometritis and embryonic loss while undertaking routine pregnancy assessments in a Standardbred mare. After a positive pregnancy diagnosis after 13 days post‐ovulation, a mare was diagnosed with endometritis and pregnancy loss associated with the growth of an unusual fungus, likely of the Acremonium spp., 28 days post‐ovulation. While fungal embryonic loss is rare, it should be considered a potential reason for pregnancy wastage in the mare.
Financial Modelling System Using Deep Neural Networks (DNNs) for Financial Risk Assessments
Authors: Naveed Hafiz Muhammad , Yanchun Pan , Memon Bilal Ahmed , Ali Shoaib , Sohu Jan Muhammad 
Published: October 2024

ABSTRACTThe FOREX market assessment is a big challenge for investors and global risk managers. However, the present study uses daily multicurrency exchange rate returns data from 2007 to 2022 to estimate the learning returns performance of the proposed model to find a safe‐haven currency for optimal investment strategy. The categorical returns are classified into good returns (GRs), bad returns (BRs) and no returns (NRs). Therefore, the present study needs to use a one‐hot‐encoding function to convert a categorical dataset into a numeric format with TensorFlow. The present study proposes a deep neural network‐based multilayer perceptron (DNN‐based MLP) with a backpropagation algorithm to estimate the learning returns performance of the proposed model to find a safe‐haven currency for optimal investment strategy. The findings showed that currency exchange rate return 2 (CERR2) is relatively a safe‐haven currency than currency exchange rate return 1 (CERR1) and currency exchange rate return 3 (CERR3). Moreover, the findings also showed that the proposed model gives optimal learning return performance. This study may assist FOREX investors to modify their investment strategies under shed light of findings of the study. In addition, the findings of the present study may also support global risk managers to revisit their hedging strategies.
Pricing and bundling decisions for complementary products in an agency selling platform with risk‐averse suppliers and stochastic demand
Authors: Hemmati M. , Ghomi S.M.T. Fatemi , Li Hongyan 
Published: October 2024

AbstractThe exponential rise of e‐commerce has prompted many companies to utilize online platforms (e‐tailers) to sell their products. Agency selling is a prevalent policy among e‐tailers where suppliers determine retail prices of their products, and the e‐tailer charges an agency rate. This paper investigates the selling format and pricing problem of two risk‐averse suppliers who sell complementary products on the e‐tailer's platform. The e‐tailer can offer products separately and as a bundle. A game‐theoretic analysis reveals that the equilibrium prices of individual products and the bundle uniquely exist. The study explores that the e‐tailer does not always benefit from a higher agency rate. Furthermore, the agency rate can influence the superiority of mixed bundling over separate selling. Moreover, a mixed‐bundling strategy may hurt the supplier's profitability which is sensitive to marginal costs and the degree of risk aversion. Finally, when demand correlation increases, the supplier sets a lower price to mitigate the risk cost.
Orthotopic liver transplantation for hepatic associated metabolic disorders
Authors: Pratschke J , Steinmüller T , Bechstein WO , Neuhaus R , Tullius SG , Jonas S , Schumacher G , Luck W , Becker M , Neuhaus P 
Published: October 2024

Hepatic associated metabolic disorders represent 5% of the indications for orthotopic liver transplantation (OLTX) according to the European Liver Transplant Registry. We studied the outcome of this group at our institution after OLTX and combined liver/kidney transplantation.Between September 1988 and January 1997, 837 OLTXS were performed in 735 patients. Patient survival and graft function at 1 yr were 91.3 and 86%, respectively. Thirty‐nine OLTXs were performed in 38 patients (15 female/23 male, median age ± SD: 35 14 yr, range 4‐60 yr) due to liver associated metabolic disorders (4.7%). Indications included Wilson's disease (n = 14), α‐1‐anti‐trypsin‐deficiency (n = 7), hemochromatosis (n = 4), erythropoetic protoporphyria (n = 4), cystic fibrosis (n = 2), Crigler‐Najjar syndrome type I (n = 1), glycogenosis type I (n = 1), ornithine‐transcarbomylase‐deficiency (n = 1). In addition 4 patients suffering from primary hyperoxaluria type I received combined liver/kidney grafts.Survival rate the 1 yr after OLTX and combined OLTX/NTX was 91.8%. Twenty patients received cyclosporin A (55%) and 17 patients tacrolimus (45%) as primary immunosuppression. The mean follow‐up was 28.6 months (range 4‐73 months). Two patients with hemochromatosis died 1 and 3 months after OLTX, respectively, from Aspergillus sepsis followed by multiorgan‐failure. One patient died of malignant lymphoma 5 months after transplantation. One patient required retransplantation 2 months after OLTX following arterial thrombosis and ischemic type biliary lesion. One year after OLTX, all patients demonstrated good graft function, liver grafts (ALT 17.9 ± 13.6 IU/L, bilirubin 0.8±0.3.mg/dl, thromboplastin time 94±15%), and combined liver/kidney grafts (creatinine 2.4±1.4 mg/dl). OLTX, respectively combined OLTX/NTX, represent a successful therapy for hepatic associated metabolic disorders. Survival rates and graft function are similar to those in liver graft recipients for established indications at our institution. OLTX seems to be an excellent treatment for hepatic based therapy resistant neurological disorders.
Lansoprazole and Ethanol Metabolism: Comparison with Omeprazole and Cimetidine
Authors: Battiston Lucia , Tulissi Patrizia , Moretti Michèle , Pozzato Gabriele 
Published: October 2024

AbstractSince some antisecretory drugs such as Cimetidine and ranitidine, interfere with ethanol metabolism by inhibition of hepatic and/or gastric alcohol dehydrogenase, wc investigated the effect of lansoprazole, a new protonic pump inhibitor, on gastric and hepatic alcohol dehydrogenase activity. Wc also compared the lansoprazole effect with that of omeprazole and Cimetidine, respectively. Ethanol blood concentration after oral intake or intravenous administration of ethanol was estimated either in normal male human volunteers or in male rats before and after one week pretreatment with lansoprazole, omeprazole and Cimetidine. Furthermore, the in vitro effect of these drugs was studied on both human and rat gastric and hepatic alcohol dehydrogenases. Finally, wc measured the effect of the treatment on the reduced hepatic glutathione to test the effects of the drugs on first‐pass metabolism of cthanol. The results reported in this paper indicate that lansoprazole, as well as omeprazole, does not affect ethanol metabolism, and that protonic pump inhibitors seem to be safer than imidazole‐derived drugs in subjects unable to reduce ethanol intake during conditions requiring acid secretion inhibition.
A Hybrid Concept Analysis of Frailty Among Older Adults Living in the Community
Authors: Fan Xing , Li Yuelin , Xu Lijuan , Li Caifu , Song Rhayun 
Published: October 2024

ABSTRACTAimTo analyse the concept of frailty through a literature review and in‐depth interviews.DesignA hybrid model of concept analysis.MethodsThe theoretical phase identified 43 articles for reviewing the definition and measurement of frailty. Seven frail older adults were invited in the fieldwork phase for in‐depth interviews. In the final analysis phase, results from the fieldwork and theoretical phases were integrated to obtain a final definition of frailty.ResultsAttributes of frailty were heterogeneous, involving dynamic/bidirectional, multidimensional and multiple systems. The antecedents of the concept were exposure to various stimuli and challenges in responding to these stimuli. Consequences included losing autonomy and adverse health outcomes. Four themes of frailty were identified based on the fieldwork data: ‘accumulation of functional decline’, ‘powerlessness of coping with’, ‘vicissitudes of lived experience’ and ‘loss of autonomy and positivity’.ConclusionsThe final definition of frailty was ‘a dynamic and fluctuating process of powerlessness to manage biopsychosocial and environmental stimuli, involving functional decline and vicissitudes of life, which results in losing autonomy and positivity or adverse health outcomes’.Implications for the Profession and/or Patient CareCharacterising the definition of frailty is essential for nurses to address the lived experiences of older adults when providing person‐centred care and for developing interventions that meet the needs of frail older adults.ImpactSince some discrepancies existed in the definition of frailty from individual perception of older adults, combined in‐depth interviews with a theoretical literature review were used to provide comprehensive insight. This concept analysis provides guidelines of training for nurses and opportunities to improving quality of life for community dwelling older adults.Reporting MethodN/A.Patient or Public ContributionNo Patient or Public Contribution.
Support for Siblings of Children With Complex Care Needs: Public Health Nurses' Perceptions of Their Role in Primary Schools
Authors: Bergvoll Lise‐Marie , Clancy Anne , Martinussen Monica , Laholt Hilde 
Published: October 2024

ABSTRACTAimTo explore the role of public health nurses (PHNs) in Norwegian primary school health services in supporting siblings who have a brother or a sister with complex care needs.DesignA qualitative, exploratory design using focus groups combined with visual methods.MethodsNineteen Norwegian PHNs participated in three focus group discussions between May and September 2022. The nurses were asked to draw themselves as PHNs working in primary schools. Braun and Clarke's reflexive thematic approach was used to analyse the transcribed interviews. The drawings were analysed using critical visual analysis methodology.ResultsThe findings revealed that PHNs in primary schools focused on establishing good relationships and found it important to be flexible and creative. However, a challenge to successful service provision in supporting siblings and their families was that the nurses lacked support for the implementation of health promotion interventions and often felt alone. The analysis elicited three main themes: ‘the importance of relationships and flexibility in meeting siblings' needs’, ‘feeling alone with responsibility for supporting siblings’ and ‘the forgotten children: a need for coordinated services’.ConclusionPHNs in school health services are in a unique position to provide support to improve siblings' mental health and well‐being. To fully benefit from PHNs' potential to support siblings, there is a need to clarify guidelines and develop evidence‐based interventions.ImpactThis study provides valuable insights for health authorities, educators and practitioners on what inhibits sibling support in Norway. The study highlights the potential for PHNs to play a significant role in delivering timely health‐promoting interventions for these siblings in school settings independent of context.Reporting MethodThis study was reported in accordance with the Consolidated Criteria for Reporting Qualitative Research (COREQ).Patient or Public ContributionNo patient or public contribution.
Deposit Competition and Mortgage Securitization
Authors: MCGOWAN DANNY , NGUYEN HUYEN , SCHAECK KLAUS 
Published: October 2024

AbstractWe study how deposit competition affects a bank's decision to securitize mortgages. Exploiting the state‐specific removal of deposit market caps across the U.S. as a source of competition, we find a 7.1 percentage point increase in the probability that banks securitize mortgage loans. This result is driven by an 11 basis point increase in deposit costs and corresponding reductions in banks' deposit holdings. Our results are strongest among banks that rely more on deposit funding. These findings highlight a hitherto undocumented and unintended regulatory cause that motivates banks to adopt the originate‐to‐distribute model.
Monetary Policy and Government Debt
Authors: CARAMP NICOLAS , FEILICH ETHAN 
Published: October 2024

AbstractWe study how the level of government debt affects the effectiveness of monetary policy, that is, the elasticity of economic aggregates to interest rate changes. We build a New Keynesian model where fiscal policy is non‐Ricardian and government debt is risk‐free. Wealth effects generated by government bonds weaken the transmission of monetary policy to output. Using data on private ownership of U.S. public debt, we find that when the debt‐to‐GDP ratio is one standard deviation above its mean, the response of industrial production and unemployment to a monetary shock decreases by 0.75pp and 0.1pp, respectively, out to a 3‐year horizon.
Violence Against Nurses During Care: A Systematic Review
Authors: Feruglio Laura , Bressan Valentina , Cadorin Lucia 
Published: October 2024

ABSTRACTAimsTo analyse and synthesise knowledge on workplace violence perpetrated by patients and caregivers against nurses, its consequences and strategies to prevent this phenomenon.DesignA systematic review of the literature was conducted following the method of the Center for Reviews and Determination and reported in accordance with the PRISMA checklist. A pre‐defined protocol was designed (PROSPERO ID: CRD42023432271).MethodsThree researchers screened eligible studies independently. The Joanna Briggs Institute Critical Appraisal for Analytical Cross‐Sectional Studies was used to assess the risk of bias within the studies included.Data SourcesQuantitative primary studies published between January 2012 and June 2023 were included through specific research strings used in the CINHAL, Scopus, PubMed and PsychInfo databases.ResultsA total of 15 studies were selected, the majority of which were cross‐sectional and observational. The consequences related to events of verbal and physical violence were highlighted, ranging from the psychological to the physical effects on nurses' mental health, for example, gastrointestinal symptoms, headache and sleep problems. Four studies analysed the strategies used to cope with such violence.ConclusionThe results showed that aggression on the part of patients affects nurses' health adversely on both a personal and a work level, and makes it necessary to pay more attention to the phenomenon and to find strategies to reduce the incidents, such as developing policies to safeguard the professionals' physical and mental health.Implications for the Profession and/or Patient CareNurses and nursing managers should be aware of violence and its consequences on the victims' health. Therefore, it is essential for nursing managers to develop effective policies to reduce violence and its consequences.
Risky Business. Interventions to Prevent Aggression Against Health Workers From Patients at Risk: An Integrative Review
Authors: McCamon Teresa , Lowe Vicki , George Rinchu , Gordon Rachel , Watson Heather 
Published: October 2024

ABSTRACTAimTo identify best practices to prevent violence against healthcare workers by patients at risk for aggression in the adult inpatient setting.DesignAn integrative review.MethodsConducted using the Johns Hopkins Evidence‐based Practice for Nurses and Healthcare Professionals Model. Title and abstract screening on 4186 articles resulted in 156 for full text review. Full text screening yielded 14 articles that met inclusion criteria.Data SourcesA search of the databases PubMed, CINAHL, Embase, and JBI from January 2019 to February 2023.ResultsThe review revealed behavioural intervention teams, environmental changes, and coordinated communication plans were the most used strategies, however none demonstrated significant decreases in violence.ConclusionsHealth systems can implement strategies shown to decrease the incidence of violence in healthcare settings globally. Lack of consistency in the evidence suggests the need for further research to assess mitigating strategies for violence against healthcare workers in inpatient hospital settings.Implications for the Profession and/or Patient CarePatient safety is a cornerstone of nursing practice; however, healthcare workers need to feel safe in their work environment. Violent events are chronically underreported, ill defined, and when reported, do not address change in the practice setting. Identifying strategies to address escalating behaviour before it results in violence is crucial for everyone's safety.ImpactThis integrative review exposes the scarcity of evidence available to address rising concerns about patients on healthcare provider violence (Type II) in the workplace. Although several assessment tools for identifying violent patients exist, evidence regarding prevention is woefully absent. The review highlights potential interventions for further study to equip healthcare workers to manage patients safely and effectively before an escalation occurs.Reporting MethodPRISMA checklist for integrative reviews.Patient or Public ContributionNo patient or public contribution was part of this review.
Validating the CogSleep Screener in older adults at a memory and cognition clinic
Authors: Kong Shawn Dexiao , Schrire Zoe Menczel , Lin Ping Hsiu , Simonetti Simone , Cross Nathan , Mowszowski Loren , Ireland Catriona , Rosenzweig Ivana , Naismith Sharon L. 
Published: October 2024

SummaryWhile sleep disturbances are prevalent in older people and are linked with poor health and cognitive outcomes, screening for the range of sleep disturbances is inefficient and therefore not ideal nor routine in memory and cognition clinic settings. We aimed to develop and validate a new brief self‐report questionnaire for easy use within memory and cognition clinics. The design for this study was cross‐sectional. Older adults (aged ≥50 in Sydney, Australia) were recruited from a memory and cognition research clinic. Participants (N = 402, mean age 67.3 years, range 50–86, 63.6% female) completed a comprehensive medical, neuropsychological, and mental health assessment, alongside self‐report instruments, including existing sleep questionnaires and a new 10‐item sleep questionnaire, the CogSleep Screener. We examined the factor structure, convergent validity, internal consistency, and discriminant validity of this novel questionnaire. Using exploratory principal component analysis, a 3‐factor solution was generated highlighting the factors of Insomnia, Rapid Eye Movement (REM) Symptoms and Daytime Sleepiness. Each factor was significantly correlated with currently used sleep questionnaires for each subdomain (all Spearman rho >0.3, all p < 0.001), suggesting good convergent validity. Internal consistency was also good (Cronbach's α = 0.73). Receiver operating characteristic curves showed good discriminative ability between participants with and without sleep disturbances (all area under curve >0.7, all p < 0.01). The CogSleep Screener has good psychometric properties in older to elderly adults attending a memory and cognition clinic. The instrument has the potential to be used in memory clinics and other clinical settings to provide quick and accurate screening of sleep disturbances.
Associations of polysomnographic measures of obstructive sleep apnea, and nocturnal oxygen saturation with incident type 2 diabetes mellitus in middle‐aged and older men
Authors: Appleton Sarah L. , Naik Ganesh , Nguyen Duc Phuc , Toson Barbara , Lechat Bastien , Loffler Kelly , Catcheside Peter G. , Vakulin Andrew , Martin Sean A. , Wittert Gary A. , Adams Robert J. 
Published: October 2024

SummaryObstructive sleep apnea (OSA) has been associated with incident type 2 diabetes mellitus (T2DM); however, few prospective epidemiological studies have accounted for important T2DM predictors including pre‐diabetes status and testosterone. Participants in the longitudinal Men Androgens Inflammation Lifestyles Environment and Stress (MAILES) study, who underwent eight‐channel home‐based polysomnography (PSG) in 2010–2011 (n = 824) and were free of diabetes at baseline were included in the analysis (n = 682). From 2015 to 2021, 78.6% (n = 536) completed at least one follow‐up assessment. Incident T2DM was determined by self‐reported doctor diagnosis, diabetes medications, plasma glucose (fasting ≥7.0 mmol/L or random ≥11.0 mmol/L) or glycated haemoglobin ≥6.5%. Conservative hierarchical Poisson regression models adjusted associations of PSG metrics (categorical and continuous) for age, waist circumference, baseline fasting glucose and testosterone concentrations. In all, 52 men (9.7%) developed T2DM over a mean (range) of 8.3 (3.5–10.5) years. Significant age‐ and waist circumference‐adjusted association of incident T2DM with rapid eye movement (REM) sleep apnea–hypopnea index (AHI) ≥20 events/h (incidence rate ratio [IRR] 1.5, 95% confidence interval [CI] 0.8–2.8; p = 0.23] and highest quartile of delta index (IRR 2.1, 95% CI 0.95–4.6; p = 0.066) were attenuated after adjustment for baseline glucose and testosterone, and the association with the lowest quartile of mean oxygen saturation persisted (IRR 4.2, 95% CI 1.7–10.3; p = 0.029). Categorical measures of AHI severity, oxygen desaturation index, and hypoxia burden index (HBI) were not independently associated with incident T2DM. Associations with T2DM were similar when continuous PSG variables were used; however, HBI was significant (IRR 1.015, 95% CI 1.006–1.024; p = 0.007). In a sub‐sample with OSA treatment data (n = 479), these significant associations persisted after excluding adequately treated OSA (n = 32). Understanding underlying OSA endotypes generating hypoxaemia may identify opportunities for diabetes prevention.