bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive efficiency in translation
Authors: Hvelplund Kristian Tangsgaard 
Published: September 2016

This article concerns the cognitive mechanisms that underlie the efficient allocation of cognitive resources during the translation process. Three indicators of efficient resource allocation are outlined and examined as correlates of translation expertise: flexibility, automaticity, and processing flow. Analyses of eye tracking and keylogging data from two groups of translators – professional translators and student translators – reveal that the more experienced group performs more efficiently. Professionals exhibit greater variation in attention unit duration, indicating greater cognitive flexibility and adaptability, while analysis of pupillary data suggests a lower cognitive load on professional translators’ cognitive systems. The two groups of translators exhibit different processing flow patterns. The study demonstrates that analyses of cognitive flexibility, cognitive automaticity, and processing flow are useful to determine processing efficiency in translation.
The brief existence of Saipan Carolinian
Authors: Ellis S. James 
Published: September 2016

Saipan Carolinian emerged as a unique Micronesian language in its own right only about 100 years ago due to a series of migrations from a vast language continuum in the western Caroline Islands to an uninhabited island several hundred miles to the north, an island today known as Saipan. In view of the very shallow history of Saipan Carolinian the value in documenting this language is not for the preservation of ancient traditional knowledge – its parent languages, with their rich ancient traditions will, in fact, likely outlive this offspring language. Rather, it is Saipan Carolinian’s inherited combination of linguistic features from its diverse but very-closely related parent languages that make it well-deserving to document. It offers valuable insights into how a blended language like Saipan Carolinian can derive phonemic features from one source language (Woleaian) and lexical features from another source language (Polowat) – two languages which are mutually unintelligible. This study also reveals that the history of migration events to Saipan is stored on the tongues of its speakers – a story which happens to be in contrast to what is believed by its speakers, but is nonetheless one that is historically accurate based on well-­documented written records.
Verbal fluency in bilingual children with Autism Spectrum Disorders
Authors: Gonzalez-Barrero Ana Maria , Nadig Aparna 
Published: September 2016

Abstract
We examine the impact of bilingualism on verbal fluency in four groups of school-age (5 to 10 years-old) children: 13 Typically-developing (TYP) monolingual children, 13 TYP bilingual children, 13 monolingual children with Autism Spectrum Disorders (ASD) and 13 bilingual children with ASD. Participants were matched on chronological age and nonverbal IQ. Verbal fluency was examined via the word association subtest of the Clinical Evaluation of Language Fundamentals (CELF-4; Semel et al., 2003). The bilingual ASD group performed unexpectedly well on the verbal fluency task, not differing from the typically-developing groups, but outperforming the monolingual ASD group with respect to number of correct words produced. These findings are in line with previous research on bilingual children with ASD (e.g., Hambly & Fombonne, 2012) and taken together suggest that bilingualism does not have a negative impact on the lexical-semantic skills of children with ASD.
Vitamin D in relation to bone health and muscle function in young female soccer players
Authors: Brännström André , Yu Ji‐Guo , Jonsson Per , Åkerfeldt Torbjörn , Stridsberg Mats , Svensson Michael 
Published: September 2016

AbstractThe present work investigated serum vitamin D (25(OH)D) status in relation to bone and muscle qualities and functions in 19 female soccer players (13–16 years) resident at northern latitude with very low sun exposure (∼32–36 h/month) during winter season (late January to early March). Serum 25(OH)D, parathyroid hormone and bone turnover markers osteocalcin (OC) and beta carboxy‐terminal collagen cross‐links (β‐Ctx), as well as body composition and muscle performance were examined. Hormones were tested using routine laboratory methods. Fat mass, lean mass, and bone mineral density in whole body, as well as femur and lumbar spine were evaluated with dual‐energy X‐ray absorptiometry. Muscle performance was assessed through isokinetic knee extension and flexion, countermovement jump, and sprint running. 25(OH)D was low (50.5 ± 12.8 nmol l−1), whereas the values of bone turnover markers were markedly high (OC: 59.4 ± 18.6 µg l−1; β‐Ctx: 1075 ± 408 ng l−1). All bone and muscle measurements were normal or above normal. 25(OH)D was not significantly correlated with most of the parameters of bone and muscle quality or function, except the knee extension time to peak torque (r = −0.50, p = .03). In conclusion, the level of vitamin D is markedly low in adolescent female soccer players during the winter in Sweden. However, vitamin D levels did not significantly correlate with measures of bone and muscle except a moderate correlation in time to peak torque in the knee extensors. The practical implication of low vitamin D levels in young growing female athletes remains unclear.
Too Burdensome to Bid: Transaction Costs and Pay‐for‐Performance Conservation
Authors: Palm‐Forster Leah H. , Swinton Scott M. , Lupi Frank , Shupp Robert S. 
Published: September 2016

AbstractIn a world free of transaction costs, reverse auctions have the potential to cost‐effectively allocate payment for environmental service contracts by targeting projects that provide the most benefit per dollar spent. However, auctions only succeed if enough farmers choose to bid so that the auctioneer can evaluate numerous projects for targeted funding. A 2014 conservation auction to allocate payments for practices that reduce phosphorus runoff in Northwest Ohio experienced very thin bidding. According to a follow‐up survey, auction participation was deterred by the perceived complexity of the bidding process and the need to negotiate with renters. Due to low participation, the actual conservation auction made payments for phosphorus reduction that were surprisingly costly at the margin. Applying a farmer behavioral model to the Western Lake Erie Basin, we simulate participation choice and cost‐effectiveness of environmental outcomes in reverse auctions and uniform payment conservation programs. Results reveal that when perceived transaction costs of bid preparation are high, reverse auctions can be less cost‐effective than spatially targeted, uniform payment programs that attract higher participation.
Supply Chain Design and Adoption of Indivisible Technology
Authors: Lu Liang , Reardon Thomas , Zilberman David 
Published: September 2016

AbstractWe develop a framework for analyzing small farms' adoption of indivisible technologies by using a threshold diffusion model. The article shows that different supply chains may emerge to enable the adoption of these technologies. When the gain from adoption is not affected by scale or ownership of the technology, independent technology dealers or larger farmers may buy the indivisible equipment that embodies the technology and rent it to farmers, or enable farmers to outsource the machine's services by supplying custom services. The article derives equilibrium prices and quantities in the output and equipment rental or outsourcing markets. The prices and quantities are a function of the heterogeneity of farmers and the features of the technology. Introducing the new indivisible technology will benefit larger adopting farmers and consumers but may hurt non‐adopters. We illustrate our conceptual findings.
Verdant: automated annotation, alignment and phylogenetic analysis of whole chloroplast genomes
Authors: McKain Michael R , Hartsock Ryan H , Wohl Molly M , Kellogg Elizabeth A 
Published: September 2016

Abstract

Motivation
Chloroplast genomes are now produced in the hundreds for angiosperm phylogenetics projects, but current methods for annotation, alignment and tree estimation still require some manual intervention reducing throughput and increasing analysis time for large chloroplast systematics projects.

Results
Verdant is a web-based software suite and database built to take advantage a novel annotation program, annoBTD. Using annoBTD, Verdant provides accurate annotation of chloroplast genomes without manual intervention. Subsequent alignment and tree estimation can incorporate newly annotated and publically available plastomes and can accommodate a large number of taxa. Verdant sharply reduces the time required for analysis of assembled chloroplast genomes and removes the need for pipelines and software on personal hardware.

Availability and Implementation
Verdant is available at: http://verdant.iplantcollaborative.org/plastidDB/. It is implemented in PHP, Perl, MySQL, Javascript, HTML and CSS with all major browsers supported.

Supplementary information
Supplementary data are available at Bioinformatics online.
IsotopicLabelling: an R package for the analysis of MS isotopic patterns of labelled analytes
Authors: Ferrazza Ruggero , Griffin Julian L , Guella Graziano , Franceschi Pietro 
Published: September 2016

Abstract

Motivation
Labelling experiments in biology usually make use of isotopically enriched substrates, with the two most commonly employed isotopes for metabolism being 2H and 13C. At the end of the experiment some metabolites will have incorporated the labelling isotope, to a degree that depends on the metabolic turnover. In order to propose a meaningful biological interpretation, it is necessary to estimate the amount of labelling, and one possible route is to exploit the fact that MS isotopic patterns reflect the isotopic distributions.

Results
We developed the IsotopicLabelling R package, a tool able to extract and analyze isotopic patterns from liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-MS (GC-MS) data relative to labelling experiments. This package estimates the isotopic abundance of the employed stable isotope (either 2H or 13C) within a specified list of analytes.

Availability and Implementation
The IsotopicLabelling R package is freely available at https://github.com/RuggeroFerrazza/IsotopicLabelling.

Supplementary information
Supplementary data are available at Bioinformatics online.
BOSS: a novel scaffolding algorithm based on an optimized scaffold graph
Authors: Luo Junwei , Wang Jianxin , Zhang Zhen , Li Min , Wu Fang-Xiang 
Published: September 2016

AbstractMotivationWhile aiming to determine orientations and orders of fragmented contigs, scaffolding is an essential step of assembly pipelines and can make assembly results more complete. Most existing scaffolding tools adopt scaffold graph approaches. However, due to repetitive regions in genome, sequencing errors and uneven sequencing depth, constructing an accurate scaffold graph is still a challenge task.ResultsIn this paper, we present a novel algorithm (called BOSS), which employs paired reads for scaffolding. To construct a scaffold graph, BOSS utilizes the distribution of insert size to decide whether an edge between two vertices (contigs) should be added and how an edge should be weighed. Moreover, BOSS adopts an iterative strategy to detect spurious edges whose removal can guarantee no contradictions in the scaffold graph. Based on the scaffold graph constructed, BOSS employs a heuristic algorithm to sort vertices (contigs) and then generates scaffolds. The experimental results demonstrate that BOSS produces more satisfactory scaffolds, compared with other popular scaffolding tools on real sequencing data of four genomes.Availability and ImplementationBOSS is publicly available for download at https://github.com/bioinfomaticsCSU/BOSS.Supplementary informationSupplementary data are available at Bioinformatics online.
A theoretical discussion on Vening Meinesz-Moritz inverse problem of isostasy
Authors: Eshagh Mehdi 
Published: September 2016

Abstract
The Moho surface can be determined according to isostatic theories, and among them, the recent Vening Meinesz-Moritz (VMM) theory of isostasy has been successfully applied for this purpose. In this paper, this method is studied from a theoretical prospective and its connection to the Airy–Heiskanen (AH) and Vening Meinesz original theories are presented. Jeffrey's inverse solution to isostasy is developed according to the recent developments of the VMM method and both are compared in similar situations. It is shown that they are generalizations of the AH model in a global and continuous domain. In the VMM spherical harmonic solution for Moho depth, the mean Moho depth contributes only to the zero-degree term of the series, while in Jeffrey's solution it contributes to all frequencies. In addition, the VMM spherical harmonic series is improved further so that the mean Moho can contribute to all frequencies of the solution. This modification makes the VMM global solution superior to the Jeffrey one, but in a global scale, the difference between both solutions is less than 3 km. Both solutions are asymptotically convergent and we present two methods to obtain smooth solutions for Moho from them.
Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer’s disease
Authors: Kandimalla Ramesh , Manczak Maria , Fry David , Suneetha Yeguvapalli , Sesaki Hiromi , Reddy P. Hemachandra 
Published: September 2016

Abstract
The purpose of our study was to understand the protective effects of a partial reduction of dynamin-related protein 1 (Drp1) in Alzheimer’s disease (AD) progression and pathogenesis. Increasing evidence suggests that phosphorylated Tau and mitochondrial abnormalities are involved in the loss of synapses, defective axonal transport and cognitive decline, in patients with AD. In the current study, we investigated whether a partial reduction of Drp1 protect neurons from phosphorylated Tau-induced mitochondrial and synaptic toxicities in AD progression. We crossed Drp1+/− mice with Tau transgenic mice (P301L line) and created double mutant (TauXDrp1+/−) mice. Using real-time RT-PCR, immunoblotting and immunostaining analyses, we measured mRNA expressions and protein levels of genes related to the mitochondrial dynamics—Drp1 and Fis1 (fission), Mfn1, Mfn2 and Opa1 (fusion), CypD (matrix), mitochondrial biogenesis—Nrf1, Nrf2, PGC1α and TFAM and synaptic—synaptophysin, PSD95, synapsin 1, synaptobrevin 1, neurogranin, GAP43 and synaptopodin in brain tissues from 6-month-old Drp1+/−, Tau, TauXDrp1+/− and wild-type mice. Using biochemical and immunoblotting methods, mitochondrial function and phosphorylated Tau were measured. Decreased mRNA and protein levels of fission and matrix and increased levels of fusion, mitochondrial biogenesis, and synaptic genes were found in 6-month-old TauXDrp1+/− mice relative to Tau mice. Mitochondrial dysfunction was reduced in TauXDrp1+/− mice relative to Tau mice. Phosphorylated Tau found to be reduced in TauXDrp1+/− mice relative to Tau mice. These findings suggest that a partial reduction of Drp1 decreases the production of phosphorylated Tau, reduces mitochondrial dysfunction, and maintains mitochondrial dynamics, enhances mitochondrial biogenesis and synaptic activity in Tau mice. Findings of this study may have implications for the development of Drp1 based therapeutics for patients with AD and other tauopathies.
The mirroring hypothesis: theory, evidence, and exceptions
Authors: Colfer Lyra J , Baldwin Carliss Y 
Published: September 2016

AbstractThe mirroring hypothesis predicts that organizational ties within a project, firm, or group of firms (e.g., communication, collocation, employment) will correspond to the technical dependencies in the work being performed. This article presents a unified picture of mirroring in terms of theory, evidence, and exceptions. First, we formally define mirroring and argue that it is an approach to technical problem-solving that conserves scarce cognitive resources. We then review 142 empirical studies, divided by organizational form into (i) industry studies, (ii) firm studies, and (iii) studies of open collaborative projects. The industry and firm studies indicate that mirroring is a prevalent pattern but not universal. However, in technologically dynamic industries, partial mirroring, where knowledge boundaries are drawn more broadly than operational boundaries, is likely to be a superior strategy. Firms can also strategically ‘break the mirror’ by implementing modular partitions within their boundaries, or by building relational contracts across their boundaries. Finally, studies of open collaborative projects, most of which focused on software, were not supportive of the hypothesis. We argue that digital technologies make possible new modes of coordination that enable groups to deviate from classical mirroring as seen in firms.
Magnetic fields in protoplanetary discs: from MHD simulations to ALMA observations
Authors: Bertrang G. H.-M. , Flock M. , Wolf S. 
Published: September 2016

Abstract
Magnetic fields significantly influence the evolution of protoplanetary discs and the formation of planets, following the predictions of numerous magnetohydrodynamic (MHD) simulations. However, these predictions are yet observationally unconstrained. To validate the predictions on the influence of magnetic fields on protoplanetary discs, we apply 3D radiative transfer simulations of the polarized emission of aligned aspherical dust grains that directly link 3D global non-ideal MHD simulations to Atacama Large Millimeter/submillimeter Array (ALMA) observations. Our simulations show that it is feasible to observe the predicted toroidal large-scale magnetic field structures, not only in the ideal observations but also with high-angular resolution ALMA observations. Our results show further that high-angular resolution observations by ALMA are able to identify vortices embedded in outer magnetized disc regions.
Self-employment as atypical or autonomous work: diverging effects on political orientations
Authors: Jansen Giedo 
Published: September 2016

Abstract
It is often held that the self-employed are an economically conservative, political right-wing class. Previous studies, however, have primarily dealt with self-employed workers as a relatively monolithic social class with shared interests as entrepreneurs and (potential) employers. But, with its recent rise, self-employment has developed into a heterogeneous employment type, with a growing number of dependent and precarious self-employed. In this article, the political preferences of people in self-employment are compared to the preferences of employees on temporary contracts. In doing so, hypotheses are tested from both classic theories on class voting, as well as theories on job precariousness and labor market vulnerabilities. For this purpose, European Social Survey Round 4 (ESS-4) data on eight West European countries are analyzed. The findings suggest that particular segments of self-employment share the characteristics of other forms of ‘atypical’ work, not only with respect to labor market insecurities, but also regarding the political orientations associated with such insecurities.
Oral Sucrose for Pain Relief During Clubfoot Casting: A Double-Blinded Randomized Controlled Trial
Authors: Milbrandt Todd , Kryscio Richard , Muchow Ryan , Walker Janet , Talwalkar Vishwas , Iwinski Henry 
Published: September 2016

Background:
Idiopathic clubfoot treatment is treated by manipulation and casting utilizing the Ponseti technique which can make the infant fussy and irritable. The goal of this study was to determine which intervention could decrease this pain response in infants undergoing Ponseti casting for idiopathic clubfeet. Our hypothesis was that the administration of oral sucrose solution or milk would be the most effective in accomplishing that goal.

Methods:
We conducted a double-blinded randomized controlled trial at a tertiary pediatric orthopaedic center on 33 children (average age=17.94 d; SD=20.51 d) undergoing clubfoot manipulation and casting and their guardians. Each cast was considered a new event and was randomized to an oral 20% sucrose solution (S), water (W), or milk (M) in a bottle (breast or nonbreast). We assessed the Neonatal Infant Pain Scale (NIPS), heart rate, and oxygen saturation before, during, and after the casting.

Results:
A total of 131 casts were randomized and 118 analyzed (37 M, 42 S, 39 W). Each child underwent an average of 3.97 casts (SD=1.74). There were no significant differences seen between the groups before casting in their mean NIPS score (M=2.2; SD=2.38, S=1.84, SD=2.18, W=1.61, SD=2.12). However during casting, mean NIPS score for both milk, 0.91 (SD=1.26, P=0.0005) and sucrose, 0.64 (SD=1.27, P<0.0001) were significantly less than water, 2.27 (SD=2.03) but not different from each other (P=0.33). Postcasting, the sucrose NIPS score, 0.69 (SD=1.53) continued to be significantly less than milk, 2.11 (SD=2.37, P=0.0065. There was no correlation between heart rate or oxygen saturation and NIPS.

Conclusions:
Sucrose solution and milk during Ponseti casting and manipulation were effective in decreasing the pain response in children undergoing manipulation and casting for clubfeet. The sucrose solution administration continued the pain relief into the postcasting period. In addition to the benefits of improving the patient experience during casting, a less irritable child may result in better casting.

Level of Evidence:
Level 1 evidence.
Hip Morphology in MPS-1H Patients: An MRI-based Study
Authors: Breyer Sandra R. , Muschol Nicole , Schmidt Mona , Rupprecht Martin , Babin Kornelia , Herrmann Jochen , Stücker Ralf 
Published: September 2016

Background:
Hip dysplasia is common in mucopolysaccharidosis type-1H (MPS-1H) patients, but its morphology is not completely understood. No magnetic resonance imaging (MRI)-based studies have been reported in the literature. The purpose of this study was to improve knowledge of hip dysplasia pathology by describing the hip morphology of these patients in MRI scans, plain radiographs, and arthrograms.

Methods:
We performed a retrospective chart review of 18 MPS-1H patients. Supine anteroposterior pelvic radiographs of 36 hips and MRI scans of 18 hips were analyzed. Six arthrographs were also available.

Results:
Plain radiographs were available for 18 patients. The mean age was 6.0 (SD=3.8) years. The mean acetabular index (AI) was 36.2 degrees (SD=5.8), and the mean migration percentage was 59.0% (SD=17.2). MRI data were available for 9 patients. The MRI findings were compared with the radiographs of the same patient. The mean AI (39.3 degrees, SD=5.8) was confirmed by the MRI findings (39.1 degrees, SD=5.5). The migration percentage was lower in the MRI scans than in the radiographs. Radiologically, the center-edge angle was negative in all patients, with a mean of −16.8 degrees (SD=7.9), and the MRI images produced a more negative value (−19.6 degrees, SD=7.6). The soft tissue coverage of the femoral head was described with the inclusion of the cartilaginous roof and labrum. The cartilaginous AI was 22.4 degrees (SD=7.5), and the labral AI was 13.5 degrees (SD=6.7). All 6 arthrograms revealed stability during dynamic testing.

Conclusions:
This study provides the first description of hip morphology in MPS-1H patients through MRI-based data. The cartilaginous coverage of the hip was increased compared with that of healthy children. The use of radiography alone may lead to a misunderstanding of hip morphology. MRI and arthrogram is highly recommended if surgery is considered.