bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sequential Reservoir Computing for Log File‐Based Behavior Process Data Analyses
Authors: Xiong Jiawei , Wang Shiyu , Tang Cheng , Liu Qidi , Sheng Rufei , Wang Bowen , Kuang Huan , Cohen Allan S. , Xiong Xinhui 
Published: September 2024

AbstractThe use of process data in assessment has gained attention in recent years as more assessments are administered by computers. Process data, recorded in computer log files, capture the sequence of examinees' response activities, for example, timestamped keystrokes, during the assessment. Traditional measurement methods are often inadequate for handling this type of data. In this paper, we proposed a sequential reservoir method (SRM) based on a reservoir computing model using the echo state network, with the particle swarm optimization and singular value decomposition as optimization. Designed to regularize features from process data through a computational self‐learning algorithm, this method has been evaluated using both simulated and empirical data. Simulation results suggested that, on one hand, the model effectively transforms action sequences into standardized and meaningful features, and on the other hand, these features are instrumental in categorizing latent behavioral groups and predicting latent information. Empirical results further indicate that SRM can predict assessment efficiency. The features extracted by SRM have been verified as related to action sequence lengths through the correlation analysis. This proposed method enhances the extraction and accessibility of meaningful information from process data, presenting an alternative to existing process data technologies.
Life‐space mobility and cognition in community‐dwelling late‐life women: A cross‐sectional analysis
Authors: Sheets Kerry M. , Kats Allyson M. , Fink Howard A. , Langsetmo Lisa , Yaffe Kristine , Ensrud Kristine E. 
Published: September 2024

AbstractBackgroundLife‐space mobility captures the daily, enacted mobility of older adults. We determined cross‐sectional associations between life‐space mobility and cognitive impairment (CI) among community‐dwelling women in the 9th and 10th decades of life.MethodsA total of 1375 (mean age 88 years; 88% White) community‐dwelling women enrolled in a prospective cohort of older women. Life‐space score was calculated with range 0 (daily restriction to one's bedroom) to 120 (daily trips leaving town without assistance) and categorized (0–20, 21–40, 41–60, 61–80, 81–120). The primary outcome was adjudicated CI defined as mild cognitive impairment or dementia; scores on a 6‐test cognitive battery were secondary outcomes.ResultsCompared to women with life‐space scores of 81–120 and after adjustment for demographics and depressive symptoms, the odds of CI was 1.4‐fold (OR 1.36, 95% CI 0.91–2.03) higher for women with life‐space scores of 61–80, twofold (OR 1.98, 95% CI 1.33–2.94) higher for women with life‐space scores of 41–60, 2.6‐fold (OR 2.62, 95% CI 1.71–4.01) higher for women with life‐space scores of 21–40, and 2.7‐fold (OR 2.71, 95% CI 1.27–5.79) higher for women with life‐space scores of 0–20. The association of life‐space scores with adjudicated CI was primarily due to higher odds of dementia; the odds of dementia versus normal cognition was eightfold (OR 8.63, 95% CI 3.20–23.26) higher among women with life‐space scores of 0–20 compared to women with life‐space scores of 81–120. Lower life‐space scores were associated in a graded manner with lower mean scores on tests of delayed recall (California Verbal Learning Test‐II delayed recall) and language and executive function (phonemic fluency, category fluency, and Trails B). Life‐space score was not associated with scores on tests of attention and working memory (forward and backward digit span).ConclusionsLower life‐space mobility is associated in a graded manner with CI among community‐dwelling White women in the 9th and 10th decades of life.
Effectiveness of Horticultural Therapy in Older Patients With Dementia: A Meta‐Analysis Systemic Review
Authors: Wang Min , Qian Ying , Yu Xiaoyun , Xing Yubo 
Published: September 2024

ABSTRACTAimOur study aims to assess the effectiveness of horticultural therapy in improving outcomes in older patients with dementia.DesignA systematic review and meta‐analysis.MethodsThe included studies comprised randomised controlled trials (RCTs) that aimed to assess the effectiveness of horticultural therapy on cognitive function in older patients with dementia. The study design and data extraction were independently conducted by two investigators, who also evaluated the risk of bias using RoB 2.0. The meta‐analysis was carried out using Stata 15.1 software.Data SourcesOn November 2023, we searched relevant English and Chinese publications in PubMed, Web of Science, Cochrane Library, Embase, CNKI and Wanfang databases.ResultsThe meta‐analysis included a total of 9 RCTs, involving 655 older patients diagnosed with dementia. The findings from these studies demonstrated that horticultural therapy had a significant positive impact on various aspects of the patients' well‐being when compared to conventional care. Specifically, it was found to improve cognitive function scores, alleviate symptoms of depression, enhance daily activities and enhance overall quality of life. When conducting a subgroup analysis, it was observed that horticultural therapy had a statistically significant effect on cognitive function in older patients with dementia when the intervention frequency was at least two times per week. Furthermore, interventions with a duration of less than 6 months were found to be more effective than those lasting 6 months or longer. Additionally, outdoor horticultural therapy was found to be superior to indoor interventions. Moreover, structured interventions were observed to yield better outcomes compared to non‐structured interventions.ConclusionMore high‐quality studies are needed to further corroborate these findings due to the low quality of the included studies. Horticultural therapy has been found to have a significantly positive impact on the cognitive function, depression status, ADL, and quality of life of older patients with dementia.Implications for the Profession and/or Patient CareWe provide references for non‐pharmacologic treatment of older patients with dementia.What Problem Did the Study Address?This study aimed to measure the efficacy of horticultural therapy in older patients with dementia across four dimensions: cognitive function, depression levels, daily living activities and overall quality of life.What Were the Main Findings?In older patients with dementia, horticultural therapy has been proven to have a significant positive impact on cognitive function, depressive status, activities of daily living and quality of life.Where and on Whom Will the Research Have an Impact?This study will inform non‐pharmacological interventions for older patients with dementia worldwide.Patient or Public ContributionNo Patient or Public Contribution.
Enhancing Growth and Health in Weanling Pigs: The Impact of Monzogranite Supplementation
Authors: No Sang Gun , Mun Jun Young , Hosseindoust Abdolreza , Ha Sang Hun , Park Se Rin , Kinara Elick , Park Jong Kyu , Seo Sung Man , Kim Jae Hwan , Park So Lim , Lee So Young , Il Lim Seong , Kim Jin Soo 
Published: September 2024

ABSTRACTMonzogranite is known for its high surface area and cation exchange capacity, which play a crucial role in ameliorating the challenges by enhancing nutrient adsorption and facilitating nutrient availability during the weaning period. Weaned crossbred piglets (Duroc × Yorkshire × Landrace), initially weighing 5.36 ± 0.26 kg, were allocated into four treatments with 6 replicates each (10 pigs per replicate). The treatments encompassed CON (basal diet), Z0.1 (0.1% monzogranite supplementation in basal diet), Z0.2 (0.2% monzogranite supplementation), and Z0.3 (0.3% monzogranite supplementation). In phase 1, a linear increase in total average daily gain (ADG) was observed across treatment groups, with a concomitant linear increase in ADG and gain‐to‐feed ratio (G/F). The overall results showed a linear increase in ADG and G/F. A linear decrease in aspartate aminotransferase and lactate dehydrogenase levels was observed across treatment groups. Conversely, no significant differences were noted in the levels of albumin, alkaline phosphatase, alanine aminotransferase, high‐density lipoprotein, low‐density lipoprotein, total cholesterol, blood urea nitrogen, triglycerides, and gamma‐glutamyl transferase among the treatment groups. Faecal scoring indicated a linear reduction in scores at Day 7 among the treatment groups. However, no significant differences were observed at Days 14 and 28. The assessment of immunoglobulins demonstrated a significant increase in both immunoglobulin G and immunoglobulin A levels in the Z0.1 treatment group compared to the CON. In both phase 1 and phase 2, a linear decrease in cortisol levels was evident. In conclusion, a linear increase in total ADG and G/F during phase 1, sustained across both phases, suggests monzogranite potential to enhance growth performance. Moreover, stress mitigation was shown through a consistent linear decrease in cortisol levels across phases. These findings underscore monzogranite multifaceted impact, emphasizing its potential as a dietary supplement to enhance growth, liver health, and stress resilience in weanling pigs.
Decrease of excessive daytime sleepiness after shunt treatment for normal pressure hydrocephalus
Authors: Lidén Simon , Lindam Anna , Farahmand Dan , Landtblom Anne‐Marie , Laurell Katarina 
Published: September 2024

SummarySleepiness and apathy are often reported in patients with normal pressure hydrocephalus. However, research on outcomes after shunt surgery has mainly focused on the classical triad symptoms, that is, gait, cognition, and bladder dysfunction. This study aimed to describe the effects of shunt treatment on excessive daytime sleepiness and whether there was a relation to changes in ventricular volume. Pre‐ and postsurgical excessive daytime sleepiness was investigated using the Epworth sleepiness scale in a sample of 32 patients with normal pressure hydrocephalus who underwent shunt surgery. Data were gathered before surgery and at 1, 2, and 3 months after surgery and with different settings of the shunt. In the total sample, the Epworth sleepiness scale improved by a median of 1.5 points at 1 month after surgery, p = 0.026. The improvement was predominately found in the group (n = 6) with high presurgical daytime sleepiness (Epworth sleepiness scale >12) (median = 12 points, p = 0.035) compared with a median change of 0 points (p = 0.47) in the group with Epworth sleepiness scale ≤12 (n = 26). Between the postsurgical follow‐ups, no further change in the Epworth sleepiness scale score was observed. The Epworth sleepiness scale score did not correlate with clinical tests nor with ventricular volume. Daytime sleepiness seems to be another domain of normal pressure hydrocephalus symptomatology in addition to the classical triad that is responsive to treatment, at least when pronounced. The Epworth sleepiness scale is a quick test to administer and could be a valuable addition to pre‐surgical screening for treatable symptoms.
Endothelial glycocalyx degradation in critically ill foals
Authors: Gomez Diego E. , Kamr Ahmed , Gilsenan William F. , Burns Teresa A. , Mudge M. C. , Hostnik Laura D. , Toribio Ramiro E. 
Published: September 2024

AbstractBackgroundEndothelial glycocalyx (EG) degradation occurs in septic humans and EG products can be used as biomarkers of endothelial injury. Information about EG biomarkers and their association with disease severity is lacking in hospitalized foals.ObjectivesMeasure serum syndecan‐1 (SDC‐1), heparan sulfate (HS), angiopoietin‐2 (ANG‐2), aldosterone (ALD), and plasma atrial natriuretic peptide (ANP) concentrations and to determine their association with disease severity and death in hospitalized foals.AnimalsNinety foals ≤3 days old.MethodsProspective, multicenter, longitudinal study. Foals were categorized into hospitalized (n = 74; 55 septic; 19 sick nonseptic) and 16 healthy foals. Serum ([SDC‐1], [HS], [ANG‐2], [ALD]) and plasma (ANP) were measured over 72 hours using immunoassays.ResultsSerum ([SDC‐1], [HS], [ANG‐2], [ALD]) and plasma (ANP) were significantly higher in hospitalized and septic than healthy foals (P < .05). Serum (ANG‐2) and plasma (ANP) were significantly higher in hospitalized nonsurvivors than in survivors (P < .05). On admission, hospitalized foals with serum (HS) > 58.7 ng/mL had higher odds of nonsurvival (odds ratio [OR] = 6.1; 95% confidence interval [CI] = 1.02‐36.7). Plasma (ANP) >11.5 pg/mL was associated with the likelihood of nonsurvival in hospitalized foals (OR = 7.2; 95% CI = 1.4‐37.4; P < .05). Septic foals with serum (ANG‐2) >1018 pg/mL on admission had higher odds of nonsurvival (OR = 6.5; 95% CI =1.2‐36.6; P < .05).Conclusion and Clinical ImportanceCritical illness in newborn foals is associated with EG degradation and injury, and these biomarkers are related to the severity of disease on admission and the outcome of sick foals.
Multiple Effects of L‐Leucine in Escherichia coli Lead to L‐Leucine‐Sensitive Growth in the Absence of Unphosphorylated PtsN
Authors: Kumar Neeraj , Sardesai Abhijit A. 
Published: September 2024

ABSTRACTIn E. coli K‐12, the absence of unphosphorylated PtsN (unphospho‐PtsN) has been proposed to cause an L‐leucine‐sensitive growth phenotype (LeuS) by hyperactivated K+ uptake mediated impairment of the expression of the ilvBN operon, encoding subunits of the L‐valine (Val)‐sensitive acetohydroxyacid synthase I (AHAS I) that renders residual AHAS activity susceptible to inhibition by Leu and K+. This leads to AHAS insufficiency and a requirement for L‐isoleucine (Ile). Herein, we provide an alternate mechanism for the LeuS of the ∆ptsN mutant. Genetic and physiological studies with suppressors of the LeuS indicate that impaired expression of the ilvBN operon jointly caused by the absence of unphospho‐PtsN and the presence of Leu coupled to Leu‐mediated repression of expression of AHAS III leads to AHAS insufficiency rendering residual AHAS activity susceptible to chronic Val stress that may be generated by exogenous Leu. Hyperactivated K+ uptake and an elevated α‐ketobutyrate level mediate elevation of ilvBN expression and alleviate the LeuS. The requirement of unphospho‐PtsN as a positive regulator of ilvBN expression may buffer Ile biosynthesis against Leu‐mediated AHAS insufficiency and protect AHAS I function from chronic endogenous Val generated by Leu and could be realized in certain environments that impair AHAS function.
Evaluating the efficacy of intermittent fasting and exercise combinations for weight loss: A network meta‐analysis
Authors: Cheng Xiaoyan , Sun Shunli , Chen Maolin , Zhou Xinyou , Rao Mingxin , Guo Dongjuan , Xie Jinfeng , Huang Qiang , Su Liqiang 
Published: September 2024

SummaryObjectiveThe purpose of this study is to utilize network meta‐analysis (NMA) to synthesize relevant randomized controlled trials (RCTs) and evaluate the most effective intermittent fasting (IF) combined with exercise interventions for weight loss.MethodsThis study searched five databases up until April 2024, obtaining RCTs that investigated the effects of intermittent fasting (IF) combined with exercise. The quality of the literature was assessed using the Cochrane tool, followed by a random‐effects statistical analysis of each intervention. Eventually, a NMA was conducted to compare the effectiveness of each intervention on weight loss, thereby determining their combined effectiveness on reducing weight.ResultsA total of nine trials, comparing 12 interventions involving 570 participants, were included. All interventions significantly reduced body weight (BW) and fat mass (FM) compared to the control (CON) group. In terms of BW reduction, the alternate‐day fasting + moderate‐intensity continuous training (ADF + MICT) intervention had the highest surface under the cumulative ranking curve average (SUCRA) score 88.1(MD: −4.44,95% CI −5.95, −2.92). Furthermore, for improving FM, the ADF + MICT intervention also had the highest SUCRA score 92.7(MD: −3.65,95% CI −5.05, −2.25), making it the optimal intervention for improving FM.ConclusionThe NMA results indicate that all interventions are effective in reducing weight. Among them, ADF + MICT is the most effective strategy for reducing BW, and it is also the best approach for improving FM.
Interpersonal determinants of diet quality and eating behaviors in people aged 13–30 years: A systematic scoping review
Authors: Braune Tanya , Kudlek Laura , Xiao Christina , Tang Hao , Demers‐Potvin Élisabeth , Harris Holly A. , Fitzsimons‐West Erin , Adams Jean , Winpenny Eleanor M. 
Published: September 2024

SummaryAdolescence is an important period of increasing independence, when adolescents experience changing influences of family and friends on their diets as they transition into adulthood. We conducted a scoping review to map the literature on interpersonal determinants of diet quality and eating behaviors among individuals aged 13–30 years. We searched seven literature databases, and following screening, 329 papers were included. Determinants were grouped according to sub‐categories of the Determinants of Nutrition and Eating framework: family structure (n = 122), social influences (n = 121), parental behaviors (n = 90), family food culture (n = 83), social support (n = 69), parental feeding styles (n = 24), parental attitudes/beliefs (n = 8), and parental resources/risk factors (n = 6), and we added two new sub‐categories: parenting style (n = 74) and partner behaviors (n = 6). Fruit/vegetable (n = 143) and sugar‐sweetened beverage (n = 102) intake were the most commonly measured diet outcomes, and breakfast consumption (n = 41) and fast food/takeaway intake (n = 39) the most commonly examined eating behaviors. This review highlights the gaps in the literature, both across the determinant sub‐categories and also the relative paucity of longitudinal evidence and lack of evidence in emerging adults, particularly outside of university settings. Future research should focus on these areas to provide stronger evidence to support better design of interventions for this age group.
Attitudes of Nursing Home Managers Regarding Cognitively Stimulating Activities in People With Dementia: A Multicentre Cross‐Sectional Study
Authors: Guicheteau Julie , Köpke Sascha , Seven Ümran Sema , Folkerts Ann‐Kristin , Kalbe Elke , Dichter Martin N. 
Published: September 2024

ABSTRACTIntroductionGroup‐based cognitive stimulation has shown short‐term benefits for the cognitive outcomes of people with dementia living in nursing homes (NH). However, group participation can be a barrier for people with advanced dementia, bedridden people or isolated people. The CogStim24 project seeks to develop and implement a new psychosocial intervention based on cognitively stimulating (CS) activities integrated into daily nursing care. As part of the intervention development process, this study aimed to survey NH managers' attitudes and describe currently used approaches to CS activities in German NH.MethodsWe performed a multicentre cross‐sectional study between September and December 2021 in randomly recruited NH in the German federal state of North Rhine‐Westphalia. NH representatives were asked to fill in a self‐developed online questionnaire. We analysed data descriptively, presenting means and standard deviations. For case scenario questions, we used a summative content analysis.ResultsWe contacted 354 NH and 106 agreed to participate. Representatives of 64 facilities completed the survey. Almost all stated to have implemented CS activities. Cognitive exercises (98%), physical and relaxation exercises (98%) and reminiscence therapy (95%) were most often used. The majority (96%) thought that CS activities could support people with dementia in maintaining their cognitive functions and that nurses should have a key role in the implementation of CS activities. More than half believed that regular CS activities were easy to implement alongside routine nursing care.ConclusionsResults indicate that CS activities are frequently applied in German NH. The positive attitude of NH managers regarding the implementation and effects of CS activities is an important implementation resource.Implications for PracticeNursing staff should be more involved in providing CS activities for people with dementia. Training, information, and implementation material must be made available for nursing staff who wish to have an active role in providing CS activities.
Enhancing safety feedback to the design of small, unmanned aircraft by joint assessment of impact area and human fatality
Authors: Jiang Chengpeng , Blom Henk , Rattanagraikanakorn Borrdephong 
Published: September 2024

AbstractAdvantages of commercial UAS‐based services come with the disadvantage of posing third party risk (TPR) to overflown population on the ground. Especially challenging is that the imposed level of ground TPR tends to increase linearly with the density of potential customers of UAS services. This challenge asks for the development of complementary directions in reducing ground TPR. The first direction is to reduce the rate of a UAS crash to the ground. The second direction is to reduce overflying in more densely populated areas by developing risk‐aware UAS path planning strategies. The third direction is to develop UAS designs that reduce the product in case of a crashing UAS, where is the size of the crash impact area on the ground, and is the probability of fatality for a person in the crash impact area. Because small UAS accident and incident data are scarce, each of these three developments is in need of predictive models regarding their contribution to ground TPR. Such models have been well developed for UAS crash event rate and risk‐aware UAS path planning. The objective of this article is to develop an improved model and assessment method for the product In literature, the model development and assessment of the latter two terms is accomplished along separate routes. The objective of this article is to develop an integrated approach. The first step is the development of an integrated model for the product . The second step is to show that this integrated model can be assessed by conducting dynamical simulations of Finite Element (FE) or Multi‐Body System (MBS) models of collision between a UAS and a human body. Application of this novel method is illustrated and compared to existing methods for a DJI Phantom III UAS crashing to the ground.