bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the effects of four growth media on potato (Solanum tubérosum L.) plantlets production in Burkina Faso
Authors: ZERBO Afoussatou , SOME Koussao , TIAMA Djakaridja , SORO Monique , OUEDRAOGO Wendpang-yidé Idrissa Caleb , TRAORE Renan Ernest 
Published: September 2024

Abstract

In Burkina Faso, potato growers face difficulties in obtaining potato seeds. In general, most of the imported seed partially meet the quality requirements of potato production. Furthermore, these seeds are not accessible in terms of cost and are unavailable in time. Therefore, local seed production is necessary. In vitro culture can remedy this problem by providing quality seeds. Thus, the goal of our study was to identify appropriated growth medium suitable for in vitro plantlet micropropagation in the process of quality potato seed production in Burkina Faso. This study was conduction in the in vitro culture laboratory of the Institut de l’Environnement et de Recherches Agricoles (INERA) at Kamboinsé.in Burkina Faso. Explants from in vitro plantlets (1 cm) of the same generation were used as plant material and transplanted onto four different media. The media used were as follows: M0 = 4.4 g/l MS medium (Murashige and Skoog 1962) + 7 g/l agar; M1 = M0 + 30 g/l table sugar; M2 = M0 + 0.5 mg/l AIB and M3 = M0 + 30 g/l sugar + 0.5 mg/l AIB. These media were prepared at pH 5.7 ± 0.1, divided into jars and autoclaved for 20 minutes at a pressure of 120 bars. Subculture in the jars was performed in a laminar flow hood. The plants were subsequently transferred to a growth room for 30 days. The results of this study indicated that M1 and M3 regenerated of the in vitro plantlets better than M0 and M2 did. Sugar likely had a positive effect on root length, stem diameter, number of nodes and number of opened leaves. These parameters strongly differentiated M1 from the other media. AIB had a positive effect on the root proliferation of in vitro regenerated plantlets in M2 medium. The combined effect of sugar and AIB had even greater effects on stem height, number of roots, number of leaves open and weight of in vitro plantlets, which strongly differentiated medium M3 from the other media. In conclusion, M3 proved to be the best media for in vitro plantlets production.
Association between the frequency of fruit intake and cognitive impairment, along with the joint impact of the frequency of fruit intake and the vision condition on cognitive impairment in Chinese seniors
Authors: Gao Jun , Zhang KeXin , Duan Jun , Chen Hanjie , Zhou Wanling , Gao Yun , Liu Yan 
Published: September 2024

Abstract

Objective: Studies that correlate the frequency of fruit intake with cognitive impairment in the senior population are lacking. In addition, the co-effects of the frequency of fruit intake and the vision condition on cognitive function remain unexplored. This study aims to investigate the relationship between the frequency of fruit intake and cognitive function, as well as the combined impact of the frequency of fruit intake and the vision condition on cognitive impairment.
Methods: The data of 7621 seniors included in the 2017-2018 China Longitudinal Healthy Lifespan Survey (CLHLS) were included. Trained investigators face-to-face survey to collect information on the frequency of fruit intake and the vision status of seniors. Binary logistic regression was used to analyze.
Results: Among chinese seniors, Low level of frequency of fruit intake had harmful effect on cognitive function(OR=1.958 95%CI=1.611-2.380). Low level of vision status had harmful effect on cognitive function(OR=9.493 95%CI=8.073-11.162). The frequency of fruit intake and the visual impairment were independently or jointly associated with cognitive function. Cognitive impairment is more likely in seniors with visual impairment when the frequency of fruit intake is rare(OR=12.855 95%CI=9.867-16.749). After stratified analysis by the vision condition, Among the senior population with visual impairment, Low level of frequency of fruit intake had harmful effect on cognitive function(OR=1.768 95%CI=1.245-2.511).
Conclusion: This study emphasizes the joint effect of the frequency of fruit intake and the vision status on cognitive ability. This study could provide a reference for the development of policies and the intervention of health promotion for seniors.
Mesenchymal stem cells govern immune cell maturation in the tumor microenvironment of oral squamous cell carcinoma
Authors: Eain Htoo Shwe , Soe Yamin , Kawai Hotaka , Sanou Sho , Min Zin Zin , Oo May Wathone , Takabatake Kiyofumi , Chang Anqi , Piao Tianyan , Nakano Keisuke , Iida Seiji , Nagatsuka Hitoshi 
Published: September 2024

Abstract

Mesenchymal stem cells (MSCs) have a role in the recruitment and modulation of immune cells due to their strong immunomodulatory effects. Due to their immunomodulatory properties, it is undeniable that MSCs could also influence the immune landscape of the tumor microenvironment (TME). Our study traced bone marrow-derived cells using GFP+ bone marrow chimeric mice. Compared to the conventional bone marrow transplantation method (BMT), our improved enzyme-cleaved bone marrow harvestation method (cBMT) allows us to collect more bone marrow-derived MSCs than BMT. Using the difference in MSC population in BMT and cBMT, we study the influences of MSCs in the immune environment of oral squamous cell carcinoma (OSCC) tumors. cBMT tumors, which have a higher population of MSCs, created tumors with a histological resemblance to wild-type mice tumors. Interestingly, recruited GFP-positive cells were higher in number in BMT tumors; however, CD45+ cells in cBMT tumors were higher. The immune cell landscape in cBMT tumors resembled more closely to that of tumors in normal wild mice. Upon detailed examination, we discovered that mature T and B cells were recruited more into cBMT tumors, while immature macrophages and myeloid-derived suppressor cells invaded more into BMT tumors. Here, we provided insight into how MSCs control the immune landscape in the tumor microenvironment.
A multi-view multi-label learning with incomplete data and self-adaptive correlations
Authors: Zhu Changming , Han Liju 
Published: September 2024

Abstract

Multi-view multi-label (MVML) learning aims to process MVML data sets represented with multiple feature sets (i.e., views) and labeled with multiple class labels. While in current scenes, MVML data sets always encounter to two main phenomena. First, for MVML data, there exist some correlations among different features, instances, labels and these correlations usually have diverse representations including within-view, cross-view, and consensus-view representations. Due to there are usually some certain relationships between information exist, thus these correlations always be changed in a self-adaptive way. Second, for some unpredictable reasons, MVML data maybe incomplete and loss some information. To address these phenomena, we pay attention to the self-adaptive measurement of those correlations in different representations and the process of incomplete data, then a multi-view multi-label learning with incomplete data and self-adaptive correlations (MVML-IDSaC) is developed. Extensive experiments on 5 MVML data sets show the superiority of the developed algorithm and some conclusions are addressed. (1) MVML-IDSaC performs better than some related competitive algorithms in statistical over AUC and precision; (2) MVML-IDSaC can process incomplete MVML data much better; (3) considering comprehensive relationships about data and its inferring results with a feasible way, the performances of a multi-view multi-label algorithm is promoted further.
Development and application of active aging scale for rural older adults living alone
Authors: Liao Shufang , Li Shasha , Dong Liying , Bao Jianyi , Li Yue , Xi Yingxue , Song Xiaofang , Guo Guojing , Yang Xinyu , Chen Yaqian 
Published: September 2024

Abstract

Background
The issue of active aging among older adults living alone in rural areas is becoming increasingly complex worldwide, and China is no exception. However, more specialized assessment tools are needed to evaluate active aging in this population. This study aims to develop and validate an active aging scale for rural older adults living alone (AAS-ROALA) in China, providing a theoretical foundation for research in this area.
Methods
The scale was developed in three phases—a preliminary version, a test version, and a final refined version—a cross-sectional survey of 480 rural older adults living alone in two cities in China in April and May 2024. The scale was tested for item analysis, content validity, structural validity, and internal reliability via a cross-sectional survey design.
Results
The newly developed scale has thirty-two items across five dimensions: independent autonomy, self-regulation, active participation, economic security, and collaborative assistance. The I-CVI ranged from 0.813–1.000, and the S-CVI/Ave was 0.929. EFA identified five factors with a cumulative variance of 61.60%. The CFA showed a good model fit. The Cronbach’s α, McDonald’s ω, split-half coefficient, and retest reliability for the total scale were 0.928, 0.935, 0.815, and 0.874, respectively.
Conclusion
The findings show that the AAS-ROALA is a valid and appropriate instrument to inform in-depth studies of active aging among rural older adults living alone.
Evaluation of the Relationship Between Retinopathy and Serum Magnesium Levels in Patients with Type 2 Diabetes Mellitus
Authors: Aslan İsmail Sefa , Baspinar Melike Mercan , Ertan Elif , Basat Okcan 
Published: September 2024

Abstract

Objective: Diabetic retinopathy, a severe complication of Type 2 Diabetes Mellitus, can lead to vision loss and blindness. Magnesium, a vital intracellular cation, plays a key role in insulin and glycaemic regulation. This study investigates the relationship between serum magnesium levels and diabetic retinopathy in T2DM patients.
Methods: A total of 118 patients who visited the Family Medicine Clinic of a tertiary hospital, were included in the study. Routine diabetes follow-up examinations and tests (blood pressure measurement, complete blood count, blood biochemistry, electrolytes, HbA1c, cholesterol panel, urinalysis, urine protein/creatinine ratio) were conducted. Retinopathy presence was determined through ophthalmologist consultations, identifying proliferative and non-proliferative diabetic retinopathy.
Results: The mean age of patients was 57.1 (10.3) years, with an average diabetes duration of 5.8 ( 4.2) years. Hypomagnesemia was observed in 19.49% of patients. Proliferative retinopathy was present in 7.63%, and non-proliferative retinopathy rate was 15.25%. Diabetes regulation status was well in 59.32%, moderate in 27.97%, and poor in 12.71% of cases. HbA1c values were significantly higher in those with hypomagnesemia (8.73±1.69) compared to those with normal magnesium levels (7.59±1.57) (p<0.05). There was a significant link between retinopathy and T2DM regulation status (p=0.009) and between hypomagnesemia and retinopathy (p<0.001). Retinopathy was found in 43.48% of patients with magnesium deficiency compared to 14.74% without it. Proliferative retinopathy risk increased 6.3 times, and non-proliferative retinopathy risk increased 5.8 times with hypomagnesemia.
Conclusion: The risk of developing retinopathy in patients with Type 2 DM increases with magnesium deficiency, and glycemic control is linked to both magnesium deficiency and retinopathy presence. It is concluded that magnesium supplementation may reduce the risk of retinopathy in DM patients with hypomagnesemia.
“This study has been presented as an oral abstract in 17th Family Medicine Autumn School, 20-24 September 2023, Concorde Congress Center, Bafra, Cyprus.”
Mito-TEMPO alleviates bleomycin-induced apoptosis and endoplasmic reticulum stress of alveolar epithelial cell by blocking oxidative stress
Authors: Wang Rui , Zhu Minghui , Lin Chenglang , Gao Minghao , Liu Yuan , Cheng Zhenshun 
Published: September 2024

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with poor prognosis. Mito-TEMPO is a superoxide dismutase mimetic with antioxidant and antifibrotic properties in renal fibrosis. However, the potential mechanism of Mito-TEMPO on IPF is still unclear. To assess the therapeutic effects of Mito-TEMPO in bleomycin (BLM)-induced pulmonary fibrosis, mice were treated with Mito-TEMPO daily for 2 weeks after BLM instillation. In addition, lung epithelial cells were incubated with BLM for 12h after Mito-TEMPO for 2 h pretreatment. And then the samples were collected. Results showed that Mito-TEMPO significantly alleviates the infiltration of inflammatory cells and the dense deposition of collagen in lungs tissues caused by BLM. At the same time, Mito-TEMPO markedly decreased the content of malondialdehyde (MDA) ,and increased the activity of superoxide dismutase (SOD) and the level of adenosine triphosphate (ATP) .Furthermore, Mito-TEMPO also effectively improved the endoplasmic reticulum stress and apoptosis of the BLM-treated mouse lung epithelial cells by inhibiting the production of mitochondria reactive oxygen species (ROS). Our findings indicate that Mito-TEMPO could be a promising therapeutic drug for IPF treatment.
Critical Role of Precursor Flux in Modulating Nucleation Density in 2D Material Synthesis Revealed by Digital Twin
Authors: Singh Akshay , Sinha Abhinav , Verma Manvi , M Nandeesh K , Kumar Keerthana , Rajan Ananth Govind 
Published: September 2024

Abstract

Chemical vapor deposition (CVD) is the most widespread approach for two-dimensional (2D) material synthesis, yet control of nucleation density remains a major hurdle towards large-area growth. We find that precursor flux, a function of gas velocity and precursor concentration, is the critical parameter controlling nucleation. We observe that for a vertically aligned substrate, the presence of a cavity/slot in the substrate-supporting plate creates an enhanced growth zone for 2D-MoS2. The effect of this confined space on nucleation density is experimentally verified by electron microscopy. To understand this intriguing observation, we developed a hyper-realistic multiphysics computational fluid dynamics model, i.e., a digital-twin of our CVD reactor, which reveals that space confinement achieves nearly-zero gas velocities. Digital twin-informed calculations indicate significantly lower metal precursor flux at the confined space during initial stages of growth, while precursor concentration is uniform across the substrate. The digital twin also makes an important prediction regarding a large time-lag between the set temperature, reactor environmental temperature, and substrate temperature, with implications for nucleation and growth. We offer a framework for designing confined spaces to control nucleation via regulating precursor flux, and for simulating reactor parameters for rapid optimization via the digital-twin model.
Antibacterial properties and biological activity of 3D-printed titanium alloy implants with a near-infrared photoresponsive surface
Authors: Wang Ming-Kang , Xu Xu 
Published: September 2024

Abstract

Purpose
SLM 3D printing technology is one of the most widely used implant-making technologies. However, the surfaces of the implants are relatively rough and bacteria can easily adhere to them; this increases the risk of postoperative infection. Therefore, we prepared a near-infrared photoresponsive nano-TiO2 coating on the surface of an SLM 3D-printed titanium alloy sheet (Ti6Al4V) via a hydrothermal method to evaluate its antibacterial properties and biocompatibility.
Methods
Using SLM technology, titanium alloy sheets were 3D printed, and a nano-TiO2 coating was prepared on its surface via a hydrothermal method to obtain Ti6Al4V@TiO2. The surface morphology, physicochemical properties, and photothermal response of the samples were observed. The Ti6Al4V groups and Ti6Al4V@TiO2 groups were cocultured with S. aureus and E. coli and exposed to 808 nm NIR light (0.8 W/cm2) and viable plate count experiments and live/dead bacterial staining were used to assess their in vitro antibacterial properties.
Results
The hydrophilicity of the nano-TiO2 coating sample significantly improved and the sample exhibited an excellent photothermal response. The temperature reached 46.9°C after 15 min of irradiation with 808 nm NIR light (0.8 W/cm2). The Ti6Al4V group showed significant antibacterial properties after irradiation with 808 nm NIR light, and the Ti6Al4V@TiO2 group also had partial antibacterial ability without irradiation. After irradiation with 808 nm NIR light, the Ti6Al4V@TiO2 group showed the strongest antibacterial properties, reaching 90.11% and 90.60% against S. aureus and E. coli, respectively.
Conclusions
A nano-TiO2 coating prepared via a hydrothermal method produced synergistic antibacterial effects after NIR light irradiation.
Evidenced Paleodrainages in Desert Regions of Saudi Arabia: Satellite Images with Field-Based Study
Authors: Saud Mashael Al 
Published: September 2024

Abstract

In Saudi Arabia, a number of linear features with uncertain origin have been observed from space, but they do not belong to any existed drainage networks. They are ancient watercourses carried water in the past during Mid-Late Quaternary (Pleistocene) and later on they were affected by global climate change and geological processes turning them into dry and buried channels filled by sediments, and then described as “Paleodrainages”. This study investigated these features primarily based on the integration of a variety of satellite images including SRTM DEM for generating detailed stream networks, ALOS-PALSAR which is capable to penetrate the surficial materials, and ASTER for detecting thermal differentiation. The novelty of this study includes the use of more than one satellite images (optical and microwave) with various spectral and optical characteristics, and the reliability of results were evidenced by field verification to investigate the lithological facies of stuffed materials into the detected paleodrainages and this has never been implemented in previous studies. Hydro-geomorphological-based categorization of these paleodrainages was carried out, indicating the presence of porous, unconsolidated sediments and rocks. From the hydrological point of view, these paleodrainages are potential for groundwater storage; and they can be also suitable sites for artificial groundwater recharge; be-sides they represent routs for saltwater intrusion on-land; and these science-based clues represent supportive element for better water resources management in Saudi Arabia.
MXene Templated Assembly of Hierarchical Al/CuO/V2C Nanothermite with Excellent Energy Release Efficiency and Highly Tunable Performance
Authors: Zhang kaili , TIAN Momang , MENG Ke-Juan , Li Yuxiang , Hussain Iftikhar 
Published: September 2024

Abstract

Nanothermite garners significant interest due to its higher energy release rate and reactivity. However, the agglomeration of nanoparticles has become the major hindrance to the energy release efficiency of nanothermite. Here, we proposed a bottom-up strategy and a facile preparation method to build a hierarchical Al/CuO/V2C nanocomposite triggered by ordered self-assembly of Al and CuO nanoparticles in ethanol suspension, using V2C MXene as a template. The unique structure is formed by the competition between the electrostatic force of Al and the covalent Cu-O-V bond to the V2C surface. The established structure as well as the high reactivity of V2C result in a complete oxidation of Al, and the heat of the reaction reaches 3156.2 J/g with a 10 wt% addition of V2C in air atmosphere, being sevenfold of the Al/CuO control group. The evolving concentration-dependent structure provides highly tunable energetic performance, which varies from a shortened 3-ms deflagration to a prolonged 16-ms combustion. The lower gas release improves the safety of Al/CuO/V2C while paving the way for promising application in microinitiators.
Ethnomedical knowledge of plants used in traditional medicine in Mampa village, Haut-Katanga province, Democratic Republic of Congo
Authors: Chiribagula Bashige Valentin , Salvius Bakari Amuri , Martin Biayi Benaja , Baptiste Lumbu Simbi Jean 
Published: September 2024

Abstract

Background
The inhabitants of the village of Mampa have developed a rich corpus of knowledge and practices for treating pathologies using plants that are worthy of preservation, perpetuation, and promotion. They draw on the region's rich biodiversity, particularly in the Miombo clear forest. However, to date, no documentation of their ethnomedicinal knowledge exists.
Methods
This descriptive cross-sectional study was conducted between November 2022 and October 2023. It employed a direct, face-to-face interview with the Mampa village population and a guide questionnaire.
Results
A total of 400 respondents were included in the study (sex ratio M/F = 0.9; mean age: 48.0 ± 4.0 years; experience: 14.5 ± 2.0 years), and the majority (93.8%) reported that they learned about plants from their families. These individuals mainly use plants as a first-line treatment (100%) and provided information on 38 taxa. The most commonly cited species were Anisophyllea pomifera and Brachystesia boehmii with 46 citations, while the most commonly used taxon was Landolphia kirkii with six recorded uses. This is the first report of Entandrophragma delevoyi and Pterocarpus brenanii as medicinal plants. Most of these taxa are trees, comprising 29 from 23 genera belonging to 24 families, with a notable prevalence of Fabaceae (10 taxa). 81 pathologies are indicated for treatment, with a predominance of gastrointestinal disorders (8 recipes, 7 taxa, 152 citations). The root is the most used organ, with 21 recipes and 14 taxa, while decoction is the most common preparation method, with 41 recipes and 19 taxa.
Conclusions
This study's findings indicate that a significant number of medicinal plants are used in traditional Mampa medicine to treat various diseases. Some of these species are endemic to the biodiversity area, while others are shared with other cultures and regions. A series of pharmacological studies are currently underway to validate some of the reported plant indications.