bluuebunny/crossref_metadata_2025_split huggingface dataset:
BUKU GIZI BRAILLE SEBAGAI MEDIA PENDIDIKAN UNTUK MENINGKATKAN PENGETAHUAN ANAK TUNANETRA
Authors: Wahyuni Resa , Prameswari Galuh Nita 
Published: September 2017

Anak tunanetra memiliki resiko yang sama seperti anak normal untuk mengalami masalah gizi karena kurangnya pengetahuan gizi, sehingga diperlukan pendidikan gizi beserta media tepat untuk dapat meningkatkan pengetahuan gizi anak-anak tunanetra. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan signifikan antara pengetahuan gizi buah dan sayur sebelum diberi dan setelah diberi media buku gizi braille pada anak tunanetra di Madrasah Ibtidaiyah Luar Biasa (MILB) Budi Asih Semarang. Jenis penelitian yang digunakan adalah pra eksperimen dengan pendekatan one group pretest posttest design. Pengambilan sampel pada penelitian ini dilakukan dengan total sampling karena jumlah populasi yang terbatas, yaitu sebanyak 7 sampel. Diperoleh rata-rata skor untuk pre test sebesar 10,57, dan rata-rata skor post test sebesar 16,71. Berdasarkan uji t test berpasangan yang telah dilakukan, diperoleh nilai sig (0,018) < 0,05 hal ini berati terdapat perbedaan yang signifikan antara skor sebelum diberi media buku gizi braille dan setelah diberi media buku gizi braille.
Children with visual impairment have the same risk as eyesight children to have a nutrition problems because the lack of nutrition knowledge, in order to the nutrition education is required with the appropriate media to be able to improve theirs nutrition knowledge. This study aimed to know the significant different about nutrient of fruits and vegetables knowledge before and after given nutrient book in children with visual impairment at Madrasah Ibtidaiyah Luar Biasa (MILB) Budi Asih Semarang. The type of this research was pre experiment with one group pretest posttest design approach. Sampling was used total sampling because the population was limited, there were 7 samples. The mean of pre test score was 10,57 dan post score was 16,71. Based on the paired t test, the value of sig (0,018) <0,05 it means there were significant differences between score before given nutrient media braille book and score after given nutrient media braille book.
HUBUNGAN STATUS VAKSINASI BCG, RIWAYAT KONTAK DAN PERSONAL HYGIENE DENGAN KUSTA DI KOTA PEKALONGAN
Authors: Susanti Kurnia Ningrum , Azam Mahalul 
Published: September 2017

Kusta masih menjadi masalah kesehatan masyarakat di berbagai negara umumnya negara berkembang, termasuk Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara status vaksinasi BCG, riwayat kontak dan personal hygiene dengan kejadian kusta. Penelitian ini merupakan penelitian analitik observasional dengan pendekatan kasus kontrol secara retrospektif. Pada penelitian ini menggunakan total sampling pada kelompok kasus dan accidental sampling pada kelompok kontrol, dengan jumlah masing-masing 64 orang. Analisis data dilakukan secara univariat, bivariat dan berstrata dengan uji chi square (α=0,05) dan menghitung nilai Odds Ratio (OR). Dari hasil penelitian didapatkan bahwa faktor yang berhubungan dengan kejadian kusta adalah status vaksinasi BCG (p=0,000;OR=3,621), riwayat kontak (p=0,000;OR=5,800) dan lama kontak (p=0,000; OR=15,815). Sedangkan personal hygiene (p=0,077) tidak berhubungan dengan kejadian kusta. Variabel umur, tingkat pendidikan dan status sosial ekonomi tidak terbukti sebagai variabel perancu dalam hubungan antara status vaksinasi BCG. Akan tetapi pendidikan merupakan variabel perancu dalam hubungan antara personal hygiene dengan kejadian kusta. Saran bagi petugas bagian P2PL adalah meningkatkan kegiatan surveilans epidemiologi penyakit kusta. Bagi kepala puskesmas diharapkan untuk meningkatkan penemuan penderita secara aktif, meningkatkan penyuluhan kepada masyarakat tentang penyakit kusta dan meningkatkan cakupan vaksinasi BCG. Bagi peneliti selanjutnya untuk menghindari bias recall dan bias seleksi.
Leprosy remains a public health problem in many developing countries, including Indonesia. The purpose of this study was to determine the relation between BCG vaccination status, contact with patient, and personal hygiene and leprosy. This study was an observational analytic study with approach case control restropectively. This study used total sampling in case group and accidental sampling in control group, in total 64 peoples each group. Data analysis used univariate, bivariate and stratified by chi square test (α = 0,05) and calculated the odd ratio (OR). The result showed that the factors related with the leprosy were BCG vaccination status (p=0,000;OR=3,621), contact with patient (p=0,000;OR=5,800) and duration of contact (p=0,000; OR=15,815). While personal hygiene was not associated with the leprosy (p=0,077). Variables of age, education and socioeconomic status did not proven as a confounding variable in relation between BCG vaccination status and leprosy. But education was confounding variable in relation between personal hygiene and leprosy. Recommendation for P2PL officer is to improve epidemiological surveillance of leprosy. For the head of the health center is expected to increase active case detection, improving counseling to society about leprosy defect and increasing the coverage of BCG vaccination. For the other researchers to avoid recall bias and selection bias.
FAKTOR KONSUMSI YANG BERHUBUNGAN DENGAN KEJADIAN GANGGUAN AKIBAT KEKURANGAN YODIUM PADA ANAK SEKOLAH DASAR (Studi Kasus di MI Depokharjo Parakan Kabupaten Temanggung)
Authors: Kusuma Septa Tiara , Budiono Irwan 
Published: September 2017

Gangguan Akibat Kekurangan Yodium (GAKY) merupakan salah satu dari empat masalah gizi utama di Indonesia. Tujuan penelitian ini adalah untuk mengetahui hubungan antara konsumsi makanan tinggi yodium, makanan yang mengandung zat goitrogenik, protein, dan pengunaan garam beryodium dengan kejadian GAKY di MI Depokharjo Parakan Kabupaten Temanggung. Jenis penelitian ini adalah observasional analitik dengan pendekatan cross sectional. Populasinya adalah seluruh siswa di MI Depokharjo sejumlah 66 siswa. Sampel penelitian sejumlah 40 orang dengan teknik two stage simple cluster sampling dan purposive sampling. Instrumen yang digunakan adalah formulir recall konsumsi 2x24 jam, food frequency questioner dan checklist. Data yang diperoleh diolah menggunakan uji statistik chi square. Dari hasil penelitian menunjukkan bahwa faktor konsumsi yang berhubungan dengan kejadian GAKY adalah konsumsi makanan yang mengandung zat goitrogenik (p value = 0,000), konsumsi protein (p value = 0,006), penggunaan garam beryodium (p value = 0,003). Variabel yang tidak berhubungan adalah konsumsi makanan tinggi yodium (p value = 1,000). Saran yang diajukan adalah bagi instansi terkait agar mengadakan penyuluhan tentang zat goitrogenik dan untuk masyarakat agar mengurangi konsumsi zat goitrogenik.

Iodium Deficiency Disorder (IDD) was one of four main problems of nutrition in Indonesia. The purpose of this research was to know the relationship between consumption of food high in iodine, food containing goitrogenik substance, protein, and use iodized salt with IDD in MI Depokharjo Parakan Regency Temanggung. Kind of research was analytic observational with cross sectional approach. The population in this research was all elementary student at MI Depokharjo many as 66 students. The sample in this research were 40 students with two stage simple cluster sampling and purposive sampling. The instruments in this research was recall consumption 2x24 jam form, food frequency questioner, and checklist. The data process used the statistic chi square. The results showed the consumption factors related with IDD was consumstion of food containing a substance goitrogenik (p value=0,000), consumtion of protein (0,006), iodized salt used (p value=0,003). And then consumtion of food high in iodine was not related with IDD (p value=1,000).Asked for aduice related to hold information abou goitrogrnik substance and to thr public to reduce consumption of food conaining goirogenik substance.
GAMBARAN STRES KERJA PEGAWAI BAGIAN REKAM MEDIS RUMAH SAKIT BHAKTI WIRATAMTAMA SEMARANG
Authors: Sartika Dewi , Sugiharto Sugiharto 
Published: September 2017

Faktor penyebab stres kerja adalah lingkungan kerja yang kurang nyaman, konsultasi yang tidak efektif dan konflik antara tuntutan keluarga dan tuntutan instansi. Penelitian kualitatif dilakukan untuk memperoleh gambaran stres kerja pegawai bagian rekam medis rumah sakit Bhakti Wiratamtama Semarang. Jenis penelitianini adalah penelitiankualitatif deskriptif menggunakan teknik snowball sampling. Informan utama berjumlah 15 pegawai dan 2 triangulasi. Hasil yang diperoleh, yaitu informan mengeluhkan mengalami stres kerja akibat rak fililng yang kurang rapi dan pengembalian dokumen rekam medis pasien yang terlambat dan lingkungan kerja yang kurang baik. Adanya pertemuan triwulan dapat mengurangi masalah yang dihadapi oleh pegawai. Saran bagi pegawai yaitu petugas filing melakukan pemilahan dokumen rekam medis antara lembar yang akan diabadikan dan dimusnahkan. Rumah sakit disarankan dalam pembersihan berkas pasien dan penataan ruang lebih ditata dengan rapi agar pegawai nyaman dalam mobilisasi dalam bekerja.

Factors that cause occupational stress are the inconvenient occupational environment, ineffective consultation
and conflict between family agency requirement. The purpose of this qualitative research is to get occupational
stress overview of medical record employee in Bhakti Wiratamtama Semarang Hospital. This research method
is qualitative research using snowball sampling. The informants consist of 15 key informants and 2
triangulation informants. The informans were complained about untidy shelves and late of medical record returning. Quarterly meeting to reduce this problem. Suggestion to employee was to sorting the medical record document, and to select wich one to be saved. Suggestion to hospital was to clean up patients documents and
tidy up the room so the employee can work with comfort.
Pengetahuan dan Sikap Terhadap Perilaku dalam Penanggulangan Malaria di Kelurahan Sukarami Kota Bengkulu
Authors: Triana Dessy , Rosana Elvira , Anggraini Rizkianti 
Published: September 2017

Indonesia merupakan salah satu negara yang masih berisiko terhadap malaria dengan prevalensi sebesar 1,4% dan angka insiden sebesar 0,3% dengan angka Annual Parasite Incidence (API) tahun 2015 sebesar 0,85%. Provinsi Bengkulu memiliki angka prevalensi sebesar 1,5% dan angka insiden sebesar 5,7% dengan angka API sebesar 2,03% yang menduduki urutan ke-6 angka API terbesar di seluruh Indonesia. Tujuan penelitian ini adalah untuk mengetahui hubungan antara pengetahuan dan sikap terhadap perilaku dalam penanggulangan Malaria. Penelitian ini merupakan observasional analitik dengan rancangan penelitian cross sectional. Sampel dipilih secara acak. Analisis data dilakukan dengan uji regresi logistik. Hasil penelitian menunjukkan bahwa terdapat hubungan bermakna antara pengetahuan tentang malaria terhadap perilaku penanggulangan malaria (p value= 0,001; OR=4,237), tetapi tidak terdapat hubungan yang signifikan antara sikap tentang malaria terhadap perilaku penanggulangan malaria (p value = 0.392). Proporsi pengaruh variabel pengetahuan dan sikap terhadap variabel perilaku penanggulangan malaria sebesar 17,9%.
Indonesia has a risk of Malaria with the prevalence of 1.4%, incidence rate of 0.3%, and Annual Parasite Incidence (API) rate in 2015 of 0.85%. Bengkulu Province had prevalence rate of 1.5% and incidence rate of 5.7% with API rate of 2.03% which ranked 6th highest API ratein Indonesia. The purpose of this study was to determine association between knowledge and attitude with behavior in Malaria prevention. This research was analytical observational study with cross sectional design. Sample was randomly selected. Data were analyzedwith logistic regression test. The results showed that there was significant association between Malaria knowledge with Malaria prevention behavior (p value = 0,001; OR = 4,237), but there was no significant association between Malaria attitude with Malaria prevention behavior (p value = 0.392). The proportion of knowledge and attitude variables’ influence to Malaria prevention behavior variable was 17,9%.
KAJIAN IMPLEMENTASI KEBIJAKAN RUANG LAKTASI DI SEKTOR PEMERINTAH DAN SWASTA
Authors: Wijaya Prawiti Sugeng , Soesanto Soesanto Soesanto 
Published: September 2017

ABSTRAK
Masalah pemberian ASI menjadi salah satu issue kesehatan di dunia. Rendahnya konsumsi ASI bagi bayi, salah satu penyebabnya adalah faktor lingkungan yang belum kondusif mendukung ibu untuk tetap dapat memberikan ASI Eksklusif. Implementasi Kebijakan Pemerintah tidak selalu berjalan sesuai dengan harapan, sehingga perlu dilakukan studi implementasi baik di sector pemerintah maupun swasta.Tujuan penelitian yaitu untuk menganalisis implementasi kebijakan ruang laktasi yang diselenggarakan pemerintah dan swasta di kabupaten Purbalingga.
Pendekatan yang digunakan adalah pendekatan kualitatif dengan desain studi kasus. Sasaran penelitian adalah pemimpin perusahaan, penanggungjawab ruang laktasi dan pengguna ruang laktasi di PT Royal Korindah dan KPP Pratama kabupaten Purbalingga dan informan tambahan dari bagian promosi kesehatan Dinas Kesehatan kabupaten Purbalingga serta bagian HPTK Dinas Tenaga Kerja kabupaten Purbalingga. Pengambilan data dilakukan melalui wawancara mendalam dan observasi sistematis.
Hasil penelitian adalah implementasi kebijakan ruang laktasi yang diselenggarakan oleh sektor pemerintah dan swasta di kabupaten Purbalingga belum dilaksanakan sesuai dengan ketentuan yang ada.

ABSTRACT
The low consumption of breast milk for infants, one reason is the environment that is not conducive factor supporting the mother to remain exclusive breastfeeding. Implementation of Government policies do not always go according to expectations. Object of this study was to analyze the implementation of lactation space policy organized by the government and private sectors in Purbalingga district.
The approach used is qualitative approach with case study research design. Goal of research is the leader of the company, responsible for lactation space and user space lactation PT Royal Korindah and STO The Purbalingga and additional informants from the health promotion Purbalingga District Health Office and the Department of Labor HPTK part Purbalingga district. Data were collected through interviews and systematic observation.
Results of the research is the implementation of space policy lactation organized by public and private sectors in Purbalingga has not been implemented in accordance with existing regulations.
HUBUNGAN TEMAN SEBAYA, CITRA TUBUH DAN POLA KONSUMSI DENGAN STATUS GIZI REMAJA PUTRI
Authors: Normate Erni Susana , Nur Marselinus Laga , Toy Sarci Magdalena 
Published: September 2017

Abstrak
Teman sebaya dan citra tubuh merupakan faktor yang dapat menyebabkan remaja putri merasa kelebihan berat badan dan merasa tidak puas terhadap bentuk tubuhnya. Remaja tersebut akan menerapkan perilaku makan yang tidak sehat yang akhirnya berdampak pada status gizi yang buruk. Tujuan penelitian ini adalah untuk menganalisis hubungan teman sebaya, citra tubuh dan pola konsumsi dengan status gizi remaja putri SMAN 1 Kupang. Metode penelitian yang digunakan adalah survei analitik dengan rancangan cross sectional study. Populasi penelitian adalah seluruh siswi yang ada di SMAN 1 Kupang dan sampel penelitian sebesar 88 responden yang diperoleh dengan teknik simple random sampling. Hasil penelitian menunjukkan bahwa variabel yang mempunyai hubungan dengan status gizi remaja putri yaitu teman sebaya sedangkan variabel yang tidak mempunyai hubungan yaitu citra tubuh dan pola konsumsi. Upaya peningkatkan pengetahuan remaja tentang diet yang benar sangat diperlukan agar tidak mudah terpengaruh oleh teman sebaya dan melakukan diet yang salah.

Abstract
Peers and body image are factors that caused adolescents to feel overweight and dissatisfied toward her body shape. Then adolescents will ted to eat unhealthy food that results in a low nutritional status. The aim of this study was to analyze the relationship of peer, body image, and consumption pattern with nutritional status of adolescents at SMAN 1 Kupang. Research method used was analytical survey with cross sectional study design. The population of this study was all students in SMAN 1 Kupang and sample of this study was 88 respondents selected by using simple random sampling technique. Peers were significantly related to nutritional status of adolescents. While the variables that had no relationship were body image and consumption pattern. The efforts to increase knowledge about proper diet is necessary for adolescents so that they could not easily affected by peers and have wrong diet.
ID3020 Stem cell transplantation for incurable diseases in children
Authors: Nguyen Liem Thanh 
Published: September 2017

Background: Stem cell transplantation has been widely performed to treat many different diseases in adults. However, its indication is still limited in children. Since 2014, we have been doing stem cell transplantation for various incurable diseases in children. The aim of our report is to evaluate safety and efficacy of stem cell transplantation for incurable diseases in children.
Results
From 2014-2017, stem cell transplantation has been performed for different conditions including :

Cerebral palsy due to oxygen deprivation, cerebral palsy related to neonatal icterus , Cerebral palsy after meningitis/encephalitis , cerebral palsy after brain trauma ,
Brain damage due to drowning
Autism
Liver cirrhosis due to biliary atresia
Bowel and urinary dysfunction after meningocele repair
Brongchopulmonary dysplasia
Intestinal neural dysplasia

There were no death related to stem cell transplantation. No severe side effects occurred. Early outcomes are promising.
Conclusion : Stem cell transplantation is safe and effectiveness in treatment of different incurable diseases in children
ID:2022 Transoral Laser Microsurgery for Early Glottic Cancer
Authors: Tran Phan Chung Thuy , Nguyen Tuan Thanh 
Published: September 2017

Background: For the treatment of early glottic cancer (T1/T2N0M0), different treatment options, such as transoral laser microsurgery, open surgical techniques, and primary radiotherapy, are under discussion. In this context, the aim of the present study was to describe oncologic results and complication rates of transoral laser microsurgery in treatment of early glottic cancer.

Methods: A prospective cohort study in Ho Chi Minh City Ear Nose Throat Hospital included early stages (T1/T2N0M0) glottic cancer patients scheduled to undergo transoral laser microsurgery from January 2016 until June 2017. Data on demographics, site and extent of disease, treatment, complication and early outcome were collected and analyzed.

Results: Twenty eight early stages glottic cancer cases were exclusively treated by TLM and included into this study, 27 (96.4%) patients were male and 1 (3.6%) were female. The mean age was 61.8 years (± 8 years). 92.9% tumors is T1 and 7.1% for T2. The presence of intraoperative complications was low, affecting only 3.6% of patients. Immediate postoperative complications occurred in 7.1%, whereas delayed complications affected 10.7% of patients, without any of them being fatal. The most frequent complication of TLM was granulation tissue formation. 30% of patients had normal voices and a further 48% had only mild or moderate voice change. At their last follow up, no patients assessed had any difficulty swallowing relating to their treatment for glottic cancer.

Conclusion: TLM has shown good results and low complication rate compared with traditional open surgery during intervention, in the immediate and delayed postoperative period and in the long-term with respect to radiotherapy, and thus shows utility as a primary treatment modality for early glottic cancer.
ID:2024 Synthesis and Characterization of PLGA-PEG Thymoquinone Nanoparticle and its Cytotoxicity Effects in Tamoxifen-resistant Breast Cancer Cells
Authors: Ahmad Rozaina , Kaus Noor Haida Mohd , Hamid Shahrul 
Published: September 2017

Background: Drug resistance has been a continuous challenge in cancer treatment. The use of nanotechnology in the development of new cancer drugs has potential. One of the extensively studied compound is thymoquinone (TQ) and this work aims to compare two types of TQ-nanoformulation and its cytotoxicity towards resistant cancer cells.
Methods: TQ-nanoparticles were prepared and optimized by using 2 different formulation with different drug to PLGA-PEG ratio (1:20 and 1:7) and different PLGA-PEG to pluronic F68 ratio (10:1 and 2:1). The morphology and size were determined using TEM and DLS. Characterization of particles were done using UV-VIS, ATR-IR, entrapment efficiency and drug release. The effects of drug, polymer and surfactants were compared between the two formulations. Cytotoxicity assay was performed using MTS assay.
Results: TEM finding showed 96% of particles produced with 1:7 drug to PLGA-PEG were less than 90 nm in size and spherical in shape. This was confirmed with DLS which showed smaller particle size than those formed with 1:20 drug to PLGA-PEG ration. Further analysis showed zeta potential was negatively charge which could facilitate cellular uptake as reported previously. In addition, PDI value was less than 0.1 in both formulations indicating monodispersed and less broad in size distribution. The absorption peak of PLGA-PEG-TQ-Nps were at 255 nm. The 1:7 drug to polymer formulation was selected for further analysis where the entrapment efficiency was 79.9% and in vitro drug release showed a maximum release of TQ at 64% respectively. Cytotoxicity result showed IC50 of TQ-nanoparticle at 20.05 µM and free TQ was 8.25 µM.
Conclusion: This study showed that nanoparticle synthesized with 1:7 drug to PLGA-PEG ratio and 2:1 PLGA-PEG to pluronic F68 were less than 100 nm and had spherical shape as confirmed with DLS. This could facilitate its transportation and absorption to reach its target. There was conserved TQ stability as exhibited by slow release of this volatile oil. Cytotoxicity effect was noted when resistant breast cancer cells were treated with these particles.
ID2017 Cytotoxic activities of Philippine marine sponges against colon cancer cells
Authors: Uy Mylene 
Published: September 2017

Although the diversity of life in the terrestrial environment is exceptional, the greatest biodiversity is in the marine environment. Among the marine organisms, the sponges (Porifera) are the most prolific sources of bioactive secondary metabolites. The Philippines, with its long coastal lines, has drawn on its marine capital only to a small extent. Only a few marine organisms (ascidians, sponges, other marine invertebrates and their associated microorganisms) collected from various parts of the Philippines have been documented and investigated in terms of their potential as source of bioactive secondary metabolites, particularly anticancer compounds. Thirty-seven sponges from the coasts off Mindanao, Philippines were collected, identifies and extracted to give a total of seventy-four polar and nonpolar extracts. The corresponding sponge extracts were screened for the sponge extracts were investigated for cytotoxicity towards colon cell lines (HCT116) using the the tetrazolium dye (3-(4,5-Dimethylthiazol-2-yl)- 2,5- diphenyltetrazolium bromide) [MTTmethod. The results indicated fifteen (15) sponge extracts to be active at 100- microgram/mL concentration among which seven (7) were still active at 10 microgram/mL while two (2) still exhibited activity at 1 microgram/mL. Further investigation of the active sponge extracts is currently in progress