bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reflections on cultural values approaches to conservation: lessons from 20 years of implementation
Authors: Infield Mark , Entwistle Abigail , Anthem Helen , Mugisha Arthur , Phillips Kathryn 
Published: August 2017

AbstractThe natural environment underpins human well-being in diverse and complex ways, providing both material and non-material benefits. Effective conservation requires context-specific understandings of human interactions with, and conceptions of, nature. A focus on how cultural values and norms frame relationships with the natural world can enhance conservation efforts, and can prevent conservation actions undermining local culture and values, providing opportunities to reinforce them instead. Conservation, including the conceptualization and management of protected areas, has the potential to support or undermine these culture–nature relationships. A cultural values approach seeks to identify, understand and integrate considerations of cultural values into the design and implementation of conservation initiatives. Such approaches can realize diverse benefits, including maintaining and enhancing local culture (as a contribution to human well-being), deepening links between communities and conservation activities; facilitating parallel conservation of nature and culture; promoting non-material as well as material natural values; and allowing specific cultural values to inform and drive conservation efforts. Cultural values approaches thus help to enhance the equity, efficacy and acceptability of conservation practice. Fauna & Flora International has implicitly and explicitly acknowledged cultural values within project design and delivery for over 20 years. In 2011 a Cultural Values Programme was established to enhance the role of cultural values of species, places and practices, and of individual and group identities, within conservation. Here we describe our evolving approach to integrating cultural values into conservation practice, provide key lessons learnt, based on specific case studies, and relate these to wider conservation policy and practice.
Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia
Authors: Bousman C. A. , Cropley V. , Klauser P. , Hess J. L. , Pereira A. , Idrizi R. , Bruggemann J. , Mostaid M. S. , Lenroot R. , Weickert T. W. , Glatt S. J. , Everall I. P. , Sundram S. , Zalesky A. , Weickert C. S. , Pantelis C. 
Published: August 2017

BackgroundTwo single-nucleotide polymorphisms (SNPs) (rs4281084 and rs12155594) within the neuregulin-1 (NRG1) gene have been associated with psychosis transition. However, the neurobiological changes associated with these SNPs remain unclear. We aimed to determine what relationship these two SNPs have on lateral ventricular volume and white matter integrity, as abnormalities in these brain structures are some of the most consistent in schizophrenia.MethodsStructural (n = 370) and diffusion (n = 465) magnetic resonance imaging data were obtained from affected and unaffected individuals predominantly of European descent. The SNPs rs4281084, rs12155594, and their combined allelic load were examined for their effects on lateral ventricular volume, fractional anisotropy (FA) as well as axial (AD) and radial (RD) diffusivity. Additional exploratory analyses assessed NRG1 effects on gray matter volume, cortical thickness, and surface area throughout the brain.ResultsIndividuals with a schizophrenia age of onset ⩽25 and a combined allelic load ⩾3 NRG1 risk alleles had significantly larger right (up to 50%, padj = 0.01) and left (up to 45%, padj = 0.05) lateral ventricle volumes compared with those with allelic loads of less than three. Furthermore, carriers of three or more risk alleles, regardless of age of onset and case status, had significantly reduced FA and elevated RD but stable AD in the frontal cortex compared with those carrying fewer than three risk alleles.ConclusionsOur findings build on a growing body of research supporting the functional importance of genetic variation within the NRG1 gene and complement previous findings implicating the rs4281084 and rs12155594 SNPs as markers for psychosis transition.
Altered functional connectivity of the subthalamus and the bed nucleus of the stria terminalis in obsessive–compulsive disorder
Authors: Cano M. , Alonso P. , Martínez-Zalacaín I. , Subirà M. , Real E. , Segalàs C. , Pujol J. , Cardoner N. , Menchón J. M. , Soriano-Mas C. 
Published: August 2017

BackgroundThe assessment of inter-regional functional connectivity (FC) has allowed for the description of the putative mechanism of action of treatments such as deep brain stimulation (DBS) of the nucleus accumbens in patients with obsessive–compulsive disorder (OCD). Nevertheless, the possible FC alterations of other clinically-effective DBS targets have not been explored. Here we evaluated the FC patterns of the subthalamic nucleus (STN) and the bed nucleus of the stria terminalis (BNST) in patients with OCD, as well as their association with symptom severity.MethodsEighty-six patients with OCD and 104 healthy participants were recruited. A resting-state image was acquired for each participant and a seed-based analysis focused on our two regions of interest was performed using statistical parametric mapping software (SPM8). Between-group differences in FC patterns were assessed with two-sample t test models, while the association between symptom severity and FC patterns was assessed with multiple regression analyses.ResultsIn comparison with controls, patients with OCD showed: (1) increased FC between the left STN and the right pre-motor cortex, (2) decreased FC between the right STN and the lenticular nuclei, and (3) increased FC between the left BNST and the right frontopolar cortex. Multiple regression analyses revealed a negative association between clinical severity and FC between the right STN and lenticular nucleus.ConclusionsThis study provides a neurobiological framework to understand the mechanism of action of DBS on the STN and the BNST, which seems to involve brain circuits related with motor response inhibition and anxiety control, respectively.
Human rights abuses at the limits of the law: Legal instabilities and vulnerabilities in the ‘Global War on Terror’
Authors: Sanders Rebecca 
Published: August 2017

AbstractLaw following and law breaking are often conceptualised as polar opposites. However, authorities in liberal democracies increasingly deploy a strategy of what I callplausible legalityin order to secure immunity and legitimacy for proscribed practices. Rather than ignore or suspend law, they construct legal justifications for human rights abuses and other dubious policies, obscuring the distinction between legal compliance and non-compliance. I argue this is possible because instabilities in legal rules make them vulnerable to manipulation and exploitation. By tracing American rationales for contentious ‘enhanced interrogation techniques’, indefinite detention, and ‘targeted killing’ practices in the ‘Global War on Terror’, I show that law need not always be abandoned or radically reconstituted to achieve troubling ends and that rule structures enable certain patterns of violation while limiting others. The international prohibition on torture is robust and universal, but provides vague definitions open to interpretation. Detention and lethal targeting regulations are jurisdictionally layered and contextually complex, creating loopholes and gaps. The article concludes by reflecting on implications for the protection of human rights. While law is not wholly indeterminate, human rights advocates must constantly advocate shared legal understandings that constrain state violence.
Reflected and transmitted second harmonics generation by an obliquely p-polarized laser pulse incident on vacuum-magnetized plasma interface
Authors: Ghorbanalilu M. , Heidari Z. 
Published: August 2017

AbstractThe transmitted and reflected second harmonics (SH) generation by an oblique p-polarized laser pulse irradiated on vacuum-magnetized plasma interface is investigated. The laser pulse propagates through a homogenous, underdense, and transversely magnetized plasma. The transverse magnetic field plays the role of a self-generated magnetic field produced in laser plasma interaction. It is shown that if the transmitted and reflected SH components investigated as a simultaneous process, the maximum SH power deviates from previous reports specially near the critical angle. The deviation increases with laser field intensity and plasma density. The results reveal that the conversion efficiency increases slightly by increasing incident angle and drastically enhances near the critical angle. We show that the transmitted SH power decreases by increasing the magnetic field strength, in contrast to the normal incidence, which the SH power is increased. The comparison revealed that the SH efficiency is greater for transmitted component, while the reflected component is more proper for technical and experimental applications. This paper not only conforms the previous reports for angle far from the critical but also modifies them for the SH generation near the critical angle. Moreover, this paper gives a new insight for SH generation by a magnetized plasma.
Genetic diversity and structure of the treeManilkara zapotain a naturally fragmented tropical forest
Authors: Martínez-Natarén Daniela A. , Parra-Tabla Víctor , Munguía-Rosas Miguel A. 
Published: August 2017

Abstract:Forest fragmentation, habitat loss and isolation may have a strong effect on biodiversity in tropical forests. This can include modification of the genetic diversity and structure of plant populations. In this study, we assessed the genetic diversity and structure of the treeManilkara zapotain 15 naturally formed fragments of semi-evergreen tropical forest, as well as in an adjacent continuous forest for comparison. Forest fragments were scattered within a matrix of wetlands and were highly variable in terms of size and degree of isolation. The naturally fragmented populations ofM.zapotahad slightly less allelic diversity (Ar: 3.4) than those of the continuous forest (Ar: 3.6), when corrected for sample size. However, populations in the fragments and continuous forest had very similar heterozygosity levels (HE: 0.59 in both cases). Low levels of genetic differentiation were observed among populations (FST: 0.026) and genetic structure was not consistent with isolation by distance, indicating high levels of gene flow. Genetic diversity was not explained by fragment size or degree of isolation. The relatively high genetic diversity and low inter-population genetic differentiation observed inM. zapotamay be the result of long-distance pollen and seed dispersal, as well as the high proximity among patches.
EXPLORING LEXICAL EFFECTS IN SECOND LANGUAGE INTERPRETATION
Authors: Kanwit Matthew , Geeslin Kimberly L. 
Published: August 2017

AbstractThe Spanish mood contrast is a good test case for research on acquiring form-meaning connections in contexts where input is variable and multiple areas of the grammar are implicated (e.g., syntax, semantics, pragmatics). Nevertheless, research on interpretation of this contrast lags and little is known about how individual lexical items and patterns of co-occurrence of adverbial clauses with subjunctive forms influence interpretation. Addressing this void, we compare interpretation of the present subjunctive by native speakers (NSs) and nonnative speakers (NNSs) at three relatively high levels of experience. Participants completed an interpretation task containing clauses with indicative and subjunctive forms paired with one of six adverbial conjunctions, categorized as co-occurring with subjunctive, indicative, or both forms. Our analysis suggests individual lexical items play a role in morphosyntactic variation and that nuanced differences in interpretation exist for NSs and highly advanced NNSs, even on items that prescriptively co-occur with only one form.
Exploiting the Implementation Gap: Policy Divergence and Industrial Upgrading in China's Wind and Solar Sectors
Authors: Nahm Jonas 
Published: August 2017

AbstractThis article argues that manufacturing policies of Chinese local governments have provided an important corrective to some of the weaknesses inherent in the central government's indigenous innovation framework, most importantly its inattention to the importance of advanced manufacturing capabilities for innovation. Based on an original dataset of over one hundred executive interviews conducted with 43 Chinese wind and solar firms, I identify both central government R&D funding and continued local government support for manufacturing as critical factors in enabling innovation among China's renewable energy firms. In particular, this article shows that firms have utilized a combination of both central and local government policies to establish unique engineering capabilities required for innovation in commercialization and scale-up to mass production. The findings suggest that continued local government support for the manufacturing economy has not undermined central government innovation policies, but has (1) broadened the range of resources available to entrepreneurial firms and (2) enabled new options for industrial upgrading that are outside the conceptualization of innovation underlying the central government's indigenous innovation framework.
Pseudomonas aeruginosa blood stream infection isolates from patients with recurrent blood stream infection: Is it the same genotype?
Authors: McCARTHY K. L. , KIDD T. J. , PATERSON D. L. 
Published: August 2017

SUMMARYThe type identity of strains of Pseudomonas aeruginosa from primary and recurrent blood stream infection (BSI) has not been widely studied. Twenty-eight patients were identified retrospectively from 2008 to 2013 from five different laboratories; available epidemiological, clinical and microbiological data were obtained for each patient. Isolates were genotyped by iPLEX MassARRAY MALDI-TOF MS and rep-PCR. This showed that recurrent P. aeruginosa BSI was more commonly due to the same genotypically related strain as that from the primary episode. Relapse due to a genotypically related strain occurred earlier in time than a relapsing infection from an unrelated strain (median time: 26 vs. 91 days, respectively). Line related infections were the most common source of suspected BSI and almost half of all BSI episodes were associated with neutropenia, possibly indicating translocation of the organism from the patient's gut in this setting. Development of meropenem resistance occurred in two relapse isolates, which may suggest that prior antibiotic therapy for the primary BSI was a driver for the subsequent development of resistance in the recurrent isolate.
Geospatial analysis of household spread of Ebola virus in a quarantined village – Sierra Leone, 2014
Authors: GLEASON B. L. , FOSTER S. , WILT G. E. , MILES B. , LEWIS B. , CAUTHEN K. , KING M. , BAYOR F. , CONTEH S. , SESAY T. , KAMARA S. I. , LAMBERT G. , FINLEY P. , BEYELER W. , MOORE T. , GAUDIOSO J. , KILMARX P. H. , REDD J. T. 
Published: August 2017

SUMMARYWe performed a spatial-temporal analysis to assess household risk factors for Ebola virus disease (Ebola) in a remote, severely-affected village. We defined a household as a family's shared living space and a case-household as a household with at least one resident who became a suspect, probable, or confirmed Ebola case from 1 August 2014 to 10 October 2014. We used Geographic Information System (GIS) software to calculate inter-household distances, performed space-time cluster analyses, and developed Generalized Estimating Equations (GEE). Village X consisted of 64 households; 42% of households became case-households over the observation period. Two significant space-time clusters occurred among households in the village; temporal effects outweighed spatial effects. GEE demonstrated that the odds of becoming a case-household increased by 4·0% for each additional person per household (P< 0·02) and 2·6% per day (P< 0·07). An increasing number of persons per household, and to a lesser extent, the passage of time after onset of the outbreak were risk factors for household Ebola acquisition, emphasizing the importance of prompt public health interventions that prioritize the most populated households. Using GIS with GEE can reveal complex spatial-temporal risk factors, which can inform prioritization of response activities in future outbreaks.
Hybrid conditional planning using answer set programming
Authors: YALCINER IBRAHIM FARUK , NOUMAN AHMED , PATOGLU VOLKAN , ERDEM ESRA 
Published: August 2017

AbstractWe introduce a parallel offline algorithm for computing hybrid conditional plans, called HCP-ASP, oriented towards robotics applications. HCP-ASP relies on modeling actuation actions and sensing actions in an expressive nonmonotonic language of answer set programming (ASP), and computation of the branches of a conditional plan in parallel using an ASP solver. In particular, thanks to external atoms, continuous feasibility checks (like collision checks) are embedded into formal representations of actuation actions and sensing actions in ASP; and thus each branch of a hybrid conditional plan describes a feasible execution of actions to reach their goals. Utilizing nonmonotonic constructs and nondeterministic choices, partial knowledge about states and nondeterministic effects of sensing actions can be explicitly formalized in ASP; and thus each branch of a conditional plan can be computed by an ASP solver without necessitating a conformant planner and an ordering of sensing actions in advance. We apply our method in a service robotics domain and report experimental evaluations. Furthermore, we present performance comparisons with other compilation based conditional planners on standardized benchmark domains.
Financial literacy and retirement planning in Finland
Authors: KALMI PANU , RUUSKANEN OLLI-PEKKA 
Published: August 2017

AbstractThis paper presents the results from the first study of financial literacy in Finland and explores the relationship between financial literacy and retirement planning in Finland. Finland is an interesting case because countervailing effects may exist: a high level of education might increase financial literacy, while the high provision of social security may decrease it and weaken its relationship with pension planning. The results indicate that the level of financial literacy in Finland is comparatively high, although it is unequally distributed among the population. With respect to pension planning, we find that there is little evidence of a relationship between the three core financial literacy questions and retirement planning; however, a statistically significant and positive relationship exists between retirement planning and an extended measure of financial literacy, consisting mostly of more demanding questions. When we split the sample by gender, we find evidence of a positive relationship between financial literacy and retirement planning among women but not among men. The results indicate that scaling down publicly guaranteed pension benefits may pose a challenge to the less financially literate segment of the population.
Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
Authors: Dubey Lalit Kumar , Karempudi Praneeth , Luther Sanjiv A. , Ludewig Burkhard , Harris Nicola L. 
Published: August 2017

AbstractLymphatic growth (lymphangiogenesis) within lymph nodes functions to promote dendritic cell entry and effector lymphocyte egress in response to infection or inflammation. Here we demonstrate a crucial role for lymphotoxin-beta receptor (LTβR) signaling to fibroblastic reticular cells (FRCs) by lymphotoxin-expressing B cells in driving mesenteric lymph node lymphangiogenesis following helminth infection. LTβR ligation on fibroblastic reticular cells leads to the production of B-cell-activating factor (BAF﻿F), which synergized with interleukin-4 (IL-4) to promote the production of the lymphangiogenic factors, vascular endothelial growth factors (VEGF)-A and VEGF-C, by B cells. In addition, the BAFF-IL-4 synergy augments expression of lymphotoxin by antigen-activated B cells, promoting further B cell–fibroblastic reticular cell interactions. These results underlie the importance of lymphotoxin-dependent B cell–FRC cross talk in driving the expansion of lymphatic networks that function to promote and maintain immune responsiveness.
Modeling a linkage between blood transcriptional expression and activity in brain regions to infer the phenotype of schizophrenia patients
Authors: Ibrahim El Chérif , Guillemot Vincent , Comte Magali , Tenenhaus Arthur , Zendjidjian Xavier Yves , Cancel Aida , Belzeaux Raoul , Sauvanaud Florence , Blin Olivier , Frouin Vincent , Fakra Eric 
Published: August 2017

AbstractHundreds of genetic loci participate to schizophrenia liability. It is also known that impaired cerebral connectivity is directly related to the cognitive and affective disturbances in schizophrenia. How genetic susceptibility and brain neural networks interact to specify a pathological phenotype in schizophrenia remains elusive. Imaging genetics, highlighting brain variations, has proven effective to establish links between vulnerability loci and associated clinical traits. As previous imaging genetics works in schizophrenia have essentially focused on structural DNA variants, these findings could be blurred by epigenetic mechanisms taking place during gene expression. We explored the meaningful links between genetic data from peripheral blood tissues on one hand, and regional brain reactivity to emotion task assayed by blood oxygen level-dependent functional magnetic resonance imaging on the other hand, in schizophrenia patients and matched healthy volunteers. We applied Sparse Generalized Canonical Correlation Analysis to identify joint signals between two blocks of variables: (i) the transcriptional expression of 33 candidate genes, and (ii) the blood oxygen level-dependent activity in 16 region of interest. Results suggested that peripheral transcriptional expression is related to brain imaging variations through a sequential pathway, ending with the schizophrenia phenotype. Generalization of such an approach to larger data sets should thus help in outlining the pathways involved in psychiatric illnesses such as schizophrenia.
The increased risk of sarcopenia in patients with cardiovascular risk factors in Suburb-Dwelling older Chinese using the AWGS definition
Authors: Han Peipei , Yu Hairui , Ma Yixuan , Kang Li , Fu Liyuan , Jia Liye , Chen Xiaoyu , Yu Xing , Hou Lin , Wang Lu , Zhang Wen , Yin Haifang , Niu Kaijun , Guo Qi 
Published: August 2017

AbstractThe aim of the present study is to investigate the relationship between sarcopenia and cardiovascular risk factors (CVRF) in the Chinese elderly. A total of 1611 elderly individuals aged ≥60 years were enrolled in this study. The well-established CVRF of diabetes, hypertensions, and dyslipidemia were assessed. Sarcopenia was defined according to the recommended algorithm of the Asian Working Group for Sarcopenia (AWGS). Multiple logistic regression analyses and the linear regressions were used to evaluate the components of CVRF and the number of CVRF of elderly patients with sarcopenia. After adjusting for potential confounders, CVRF was associated with a high prevalence of sarcopenia in elderly Chinese populations. Furthermore, diabetes and hypertension, but not dyslipidemia, were found to be significantly associated with sarcopenia. The OR and 95% CI for sarcopenia of the participants with 1, 2, and 3 features of CVRF were 2.27(1.14–4.48), 4.13(1.80–9.46), and 4.90(1.01–23.81), respectively. A linear increase in the prevalence of sarcopenia was found to be associated with the number of CVRF components in the elderly population (P values for the trends < 0.001). Knowledge of known CVRF, particularly diabetes and hypertension, may help predict the risk for sarcopenia in the elderly.