bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Markovian analytical framework for public‐safety video sharing by device‐to‐device communications
Authors: Zhao Quanxin , Han Shuai , Mao Yuming , Leng Supeng , Min Geyong , Hu Jia , Najjari Noushin 
Published: February 2017

SummaryMonitoring video of city surveillance camera plays an important role in public security and disaster relief, which is often used by first responder teams, such as firefighters and police officers. The first responders in emergency situations require consistent connection with one another and request the remote real‐time monitoring video for effective cooperation and coordination. However, the capacity and privacy of public wireless networks fail to satisfy the requirements in many emergency scenarios, which often leads to exceptionally high traffic loads and insecurity. Device‐to‐device (D2D) communications have been deemed a key solution for this problem, as responders can use D2D links for traffic offloading and secure communications. To investigate the D2D‐based solution for public safety video sharing, this paper focuses on the Focus Geographical Area (FGA) video consisting of multiple camera streams requiring higher bandwidth consumption than that of the traditional single‐camera stream, which attracts a large number of contents delivery requests in emergency situations. This paper develops a new Traffic Burden Switching Markovian (TBSM) model to evaluate the performance of transmitting real‐time FGA video in wireless networks with D2D communications. First, a novel D2D area model is introduced to characterize link‐switching in wireless D2D communication networks. Based on the proposed D2D area model, the state and transition matrix of TBSM model are then derived by jointly considering user mobility, link‐switching, and FGA video view‐switching. Thereafter, some key performance metrics including system offloading ratio, D2D link‐switching ratio, and view‐switching ratio are derived on the basis of coverage probability and ergodic rate. The performance results show the significant varying performance among D2D areas with different geographical locations in D2D enabled wireless networks, which is referred to as multi‐D2D‐area diversity. The excellent match between simulation and model results validates the accuracy of the TBSM model, which can be used to provide guidelines for the deployment and optimization of future wireless video networks with D2D communications.
CBMR: An optimized MapReduce for item‐based collaborative filtering recommendation algorithm with empirical analysis
Authors: Li Chenyang , He Kejing 
Published: February 2017

SummaryItem‐based collaborative filtering (CF) is a model‐based algorithm for making recommendations. In the algorithm, the similarity between items are calculated by using a number of similarity measures, and then these similarity values are used to predict ratings for users. However, if the number of items and users grows to millions, the scalability and the processing efficiency of item‐based CF can be hindered by some hardware constraints. To solve this problem, we propose an optimized MapReduce for item‐based CF algorithm integrated with empirical analysis. Through extensive experiments on real‐world datasets, we demonstrate the advantages of our approach by evaluating its execution time and by comparing its shuffle phase overhead with the conventional methods. The experimental results suggest that our approach has better performance when processing large‐scale datasets.
Feasibility of a Supporting‐Salt‐Free Nonaqueous Redox Flow Battery Utilizing Ionic Active Materials
Authors: Milshtein Jarrod D. , Fisher Sydney L. , Breault Tanya M. , Thompson Levi T. , Brushett Fikile R. 
Published: February 2017

AbstractNonaqueous redox flow batteries (NAqRFBs) are promising devices for grid‐scale energy storage, but high projected prices could limit commercial prospects. One route to reduced prices is to minimize or eliminate the expensive supporting salts typically employed in NAqRFBs. Herein, the feasibility of a flow cell operating in the absence of supporting salt by utilizing ionic active species is demonstrated. These ionic species have high conductivities in acetonitrile (12–19 mS cm−1) and cycle at 20 mA cm−2 with energy efficiencies (>75 %) comparable to those of state‐of‐the‐art NAqRFBs employing high concentrations of supporting salt. A chemistry‐agnostic techno‐economic analysis highlights the possible cost savings of minimizing salt content in a NAqRFB. This work offers the first demonstration of a NAqRFB operating without supporting salt. The associated design principles can guide the development of future active species and could make NAqRFBs competitive with their aqueous counterparts.
Morpheme‐based Reading and Spelling in Italian Children with Developmental Dyslexia and Dysorthography
Authors: Angelelli Paola , Marinelli Chiara Valeria , De Salvatore Marinella , Burani Cristina 
Published: February 2017

Italian sixth graders, with and without dyslexia, read pseudowords and low‐frequency words that include high‐frequency morphemes better than stimuli not including any morpheme. The present study assessed whether morphemes affect (1) younger children, with and without dyslexia; (2) spelling as well as reading; and (3) words with low‐frequency morphemes. Two groups of third graders (16 children with dyslexia and dysorthography and 16 age‐matched typically developing children) read aloud and spelt to dictation pseudowords and words. Pseudowords included (1) root + suffix in not existing combinations (e.g. lampadista, formed by lampad‐, ‘lamp’, and ‐ista, ‘‐ist’) and (2) orthographic sequences not corresponding to any Italian root or suffix (e.g. livonosto). Words had low frequency and included: (1) root + suffix, both of high frequency (e.g. bestiale, ‘beastly’); (2) root + suffix, both of low frequency (e.g. asprigno, ‘rather sour’); and (3) simple words (e.g. insulso, ‘vapid’). Children with dyslexia and dysorthography were less accurate than typically developing children. Root + suffix pseudowords were read and spelt more accurately than non‐morphological pseudowords by both groups. Morphologically complex (root + suffix) words were read and spelt better than simple words. However, task interacted with morphology: reading was not facilitated by low‐frequency morphemes. We conclude that children acquiring a transparent orthography exploit morpheme‐based reading and spelling to face difficulties in processing long unfamiliar stimuli. Copyright © 2017 John Wiley & Sons, Ltd.
Paleokarst of the Lianglitage Formation related to tectonic unconformity at the top of the Ordovician in the eastern Tazhong Uplift, Tarim Basin, NW China
Authors: Gao Da , Lin Changsong , Hu Mingyi , Yang Haijun , Huang Lili 
Published: February 2017

The Lianglitage Formation (also named Lianglitag Formation) is an important hydrocarbon reservoir in the Tarim Basin; the reef and shoal facies of this formation have previously been extensively investigated. The paleokarst of the formation related to a tectonic unconformity at the top of the Ordovician (Tg5) has, however, not been widely investigated. In this paper, we undertake a comprehensive study of the paleokarst by an integrated analysis of seismic data, well‐logging data, and core data. Several geomorphologic units that formed at the end of the Ordovician period are identified, including a fault‐thrust uplift high, inter‐uplifts sag, uplift platform, and fault‐thrust anticline; these units are controlled by west–east and northwest–southeast striking faults. The thickness of erosion is estimated to be 200 to 700 meters. The paleokarst is characterized by large and small caves, dense vugs, and dissolution fractures. Large caves predominantly developed in exposed areas and on the slopes. Dense vugs and small caves, features that contribute to premium hydrocarbon reservoirs, are generally tens of meters away from the unconformity, whereas dissolution fractures, predominantly filled by mud and silts, are situated in close proximity to the unconformity and faults. Four karst zones can be identified from vertical profiles: weathered crust (1–2 m thick), vertical infiltration zone (tens of meters thick), phreatic zone (tens to hundreds of meters thick), and a bottom zone that is largely unaffected by karstification. The karst of the Lianglitage Formation at the end of the Ordovician was mainly controlled by tectonic movement, paleogeomorphology, lithofacies, faults, and fractures. The karstification process is summarized in a karst model.
Sensory tractography and robot‐quantified proprioception in hemiparetic children with perinatal stroke
Authors: Kuczynski Andrea M. , Carlson Helen L. , Lebel Catherine , Hodge Jacquie A. , Dukelow Sean P. , Semrau Jennifer A. , Kirton Adam 
Published: February 2017

AbstractPerinatal stroke causes most hemiparetic cerebral palsy, resulting in lifelong disability. We have demonstrated the ability of robots to quantify sensory dysfunction in hemiparetic children but the relationship between such deficits and sensory tract structural connectivity has not been explored. It was aimed to characterize the relationship between the dorsal column medial lemniscus (DCML) pathway connectivity and proprioceptive dysfunction in children with perinatal stroke. Twenty‐nine participants (6–19 years old) with MRI‐classified, unilateral perinatal ischemic stroke (14 arterial, 15 venous), and upper extremity deficits were recruited from a population‐based cohort and compared with 21 healthy controls. Diffusion tensor imaging (DTI) defined DCML tracts and five diffusion properties were quantified: fractional anisotropy (FA), mean, radial, and axial diffusivities (MD, RD, AD), and fiber count. A robotic exoskeleton (KINARM) tested upper limb proprioception in an augmented reality environment. Correlations between robotic measures and sensory tract diffusion parameters were evaluated. Lesioned hemisphere sensory tracts demonstrated lower FA and higher MD, RD, and AD compared with the non‐dominant hemisphere of controls. Dominant (contralesional) hemisphere tracts were not different from controls. Both arterial and venous stroke groups demonstrated impairments in proprioception that correlated with lesioned hemisphere DCML tract diffusion properties. Sensory tract connectivity is altered in the lesioned hemisphere of hemiparetic children with perinatal stroke. A correlation between lesioned DCML tract diffusion properties and robotic proprioceptive measures suggests clinical relevance and a possible target for therapeutic intervention. Hum Brain Mapp 38:2424–2440, 2017. © 2017 Wiley Periodicals, Inc.
Anomalous single‐subject based morphological cortical networks in drug‐naive, first‐episode major depressive disorder
Authors: Chen Taolin , Kendrick Keith M. , Wang Jinhui , Wu Min , Li Kaiming , Huang Xiaoqi , Luo Yuejia , Lui Su , Sweeney John A. , Gong Qiyong 
Published: February 2017

AbstractMajor depressive disorder (MDD) has been associated with disruptions in the topological organization of brain morphological networks in group‐level data. Such disruptions have not yet been identified in single‐patients, which is needed to show relations with symptom severity and to evaluate their potential as biomarkers for illness. To address this issue, we conducted a cross‐sectional structural brain network study of 33 treatment‐naive, first‐episode MDD patients and 33 age‐, gender‐, and education‐matched healthy controls (HCs). Weighted graph‐theory based network models were used to characterize the topological organization of brain networks between the two groups. Compared with HCs, MDD patients exhibited lower normalized global efficiency and higher modularity in their whole‐brain morphological networks, suggesting impaired integration and increased segregation of morphological brain networks in the patients. Locally, MDD patients exhibited lower efficiency in anatomic organization for transferring information predominantly in default‐mode regions including the hippocampus, parahippocampal gyrus, precuneus and superior parietal lobule, and higher efficiency in the insula, calcarine and posterior cingulate cortex, and in the cerebellum. Morphological connectivity comparisons revealed two subnetworks that exhibited higher connectivity strength in MDD mainly involving neocortex‐striatum‐thalamus‐cerebellum and thalamo‐hippocampal circuitry. MDD‐related alterations correlated with symptom severity and differentiated individuals with MDD from HCs with a sensitivity of 87.9% and specificity of 81.8%. Our findings indicate that single subject grey matter morphological networks are often disrupted in clinically relevant ways in treatment‐naive, first episode MDD patients. Circuit‐specific changes in brain anatomic network organization suggest alterations in the efficiency of information transfer within particular brain networks in MDD. Hum Brain Mapp 38:2482–2494, 2017. © 2017 Wiley Periodicals, Inc.
Effect of a hallucinogenic serotonin 5‐HT2A receptor agonist on visually guided, hippocampal‐dependent spatial cognition in C57BL/6J mice
Authors: Zhang Gongliang , Cinalli David , Stackman Robert W. 
Published: February 2017

ABSTRACTBy acting on serotonin 5‐HT2A receptors (5‐HT2ARs), serotonergic psychedelic drugs induce perceptual and visual hallucinations by increasing neuronal excitability and altering visual‐evoked neuronal responses. The present study was designed to examine whether the perceptual alterations induced by a serotonergic psychedelic drug would affect the integrity of hippocampal‐dependent, visually guided spatial cognition. phenylalkylamine hallucinogen TCB‐2 is a selective agonist of 5‐HT2ARs. Mice received TCB‐2 (1.0 mg kg−1, i.p.), and spatial behaviors and hippocampal electrophysiological responses were measured with water maze tasks and in vivo single‐unit recording, respectively. TCB‐2 did not affect visual cue approach behavior in the visible platform water maze, but increased the latency of trained mice to initiate goal‐directed swimming during a probe test in the hidden platform Morris water maze, which could be prevented by 5‐HT2AR antagonist MDL 11,939. Interestingly, TCB‐2 did not affect the efficiency of the swim path or the proper use of distal visual cues during the probe test. Hippocampal place cell activity is considered to represent spatial and context‐specific episodic memory. Systemic TCB‐2 did not affect previously established place fields of CA1 neurons in mice exploring a familiar environment, or the remapping of place cells when the mice explored a novel environment. However, TCB‐2 impaired the long‐term stability of place fields for the novel environment initially encoded under the influence of TCB‐2, which could be prevented by 5‐HT2AR antagonist MDL 11,939. Our data indicate that hallucinogenic 5‐HT2AR agonist delays the initiation of spatial search behavior, but does not impair the use of visual cues to guide goal‐directed spatial behavior. Moreover, activation of 5‐HT2ARs does not impair the coding and retrieval of spatial information, but impairs the long‐term stability of new formed place fields of CA1 neurons. © 2017 Wiley Periodicals, Inc.
Uptake of cervical cancer screening among the migrant population of Prato Province, Italy
Authors: Comparetto Ciro , Epifani Cristina , Manca Maria C. , Lachheb Abdelghani , Bravi Stefano , Cipriani Francesco , Bellomo Francesco , Olivieri Simone , Fiaschi Chiara , Di Marco Laura , Nardi Valentina , Spinelli Giansenio , Borruto Franco 
Published: February 2017

AbstractObjectiveTo determine the level of participation in cervical cancer screening among the migrant population of Prato Province, Italy.MethodsA retrospective cross‐sectional study was conducted using data for women aged 25–64 years who were resident in one of the municipalities of Prato Province and had received at least one invitation to undergo a cervical cancer screening test. Data were extracted from both the Local Health Unit Serviceable Registry and cervical cancer screening archives for the period July 1, 2004, to June 30, 2007.ResultsOf the 69 459 residents eligible for cervical cancer screening, 7339 (10.6%) did not have Italian citizenship. Adherence with cervical cancer screening among the migrant population was lower than that of the Italian resident population: uptake increased from 52.4% in 2004 to 57.3% in 2007 among the Italian resident population, but decreased from 31.4% to 28.2% among migrants.ConclusionThe migrant population of Prato Province has decreased adherence with cervical cancer screening.
Precoating of biphasic calcium phosphate bone substitute with atelocollagen enhances bone regeneration through stimulation of osteoclast activation and angiogenesis
Authors: Kim Beom‐Su , Yang Sun‐Sik , Lee Jun 
Published: February 2017

AbstractType I collagen (Col) is a naturally polymerizing protein and important extracellular matrix bone component. The aim of this study was to improve bone regeneration capacity by precoating the surface of biphasic calcium phosphate (BCP) granules with AT‐Col, and evaluating its biological effects. BCP granules were precoated with AT‐Col using adsorption and lyophilization method. Morphology of AT‐Col precoated surfaces was observed using scanning electron microscopy (SEM). Biocompatibility and osteogenic activity of AT‐Col were determined in vitro with human mesenchymal stem cell (hMSCs). In vivo bone healing efficiency and related biological effects were determined using a rabbit calvarial defect model. SEM results revealed numerous irregularly distributed AT‐Col polymer clusters on BCP granule surface. Biocompatibility experiments demonstrated that AT‐Col was non‐cytotoxic, and that cell proliferation, adhesion, and osteogenic activity were improved by AT‐Col precoating. After in vivo surgical implantation into bone defects, new bone formation was improved by AT‐Col granule precoating. Specifically, 8 weeks post‐surgery, percentage bone volume was significantly higher in AT‐Col/BCP animals (35.02 ± 1.89%) compared with BCP‐treated animals (8.94 ± 1.47%) (p < 0.05). Furthermore, tartrate‐resistant acid phosphatase staining and CD31 immunohistochemical staining revealed that osteoclast activation and new blood vessel formation in vivo were also induced by AT‐Col precoating. Collectively, these data indicate that AT‐Col/BCP may be potentially used as a bone substitute to enable effective bone regeneration through enhanced new blood vessel formation and osteoclast activation. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1446–1456, 2017.
Effects of an endodontic auxiliary chemical substance on the bond strength of two methacrylate‐based endodontic sealers to dentin
Authors: Fuzinatto Roger Nicolini , Farina Ana Paula , Souza Matheus Albino , Miyagaki Daniela Cristina , Randi Ferraz Caio Cézar , Cecchin Doglas 
Published: February 2017

AbstractPurposeTo evaluate the influence of irrigation protocols and drying procedures on the bond strength of two methacrylate‐based sealers to dentin and the associated failure pattern using scanning electron microscopy (SEM).Materials and MethodsFifty single‐rooted human teeth were prepared with an irrigation protocol using either 5.25% sodium hypochlorite (NaOCl) or 2% chlorhexidine (CHX) and 17% EDTA (ethylenediaminetetraacetic acid) for smear layer removal. The following subgroups were also created based on drying of the root canal walls: paper points, the canals were blot dried with paper points with the last one appearing dry; or, ethanol, excess distilled water was removed with paper points followed by dehydration with 95% ethanol for 1 min and blotting with paper points. Each group was divided into two subgroups on the basis of the root canal sealer: EndoREZ and RealSeal SE. Bond strength was measured by the push‐out test. The data were analyzed by ANOVA/Tukey HSD (α = 0.05). Failure patterns were classified as adhesive, cohesive, and mixed in the SEM analysis. The failure mode was evaluated by the chi‐squared test (α = 0.05).ResultsThe roots irrigated with NaOCl showed significantly lower bond strength than the roots irrigated with CHX (p < .05). RealSeal SE showed higher bond strength when compared with EndoREZ (p < .05). The highest values of bond strength were in the CHX and ethanol groups with RealSeal SE (p < .05). An increase in adhesive failure was observed in the NaOCl and EDTA group.ConclusionsThe bond strength of both methacrylate‐based sealers is influenced by the irrigant protocol.
Pharmacological inhibition of myostatin protects against skeletal muscle atrophy and weakness after anterior cruciate ligament tear
Authors: Wurtzel Caroline NW , Gumucio Jonathan P , Grekin Jeremy A , Khouri Roger K , Russell Alan J , Bedi Asheesh , Mendias Christopher L 
Published: February 2017

ABSTRACTAnterior cruciate ligament (ACL) tears are among the most frequent knee injuries in sports medicine, with tear rates in the US up to 250,000 per year. Many patients who suffer from ACL tears have persistent atrophy and weakness even after considerable rehabilitation. Myostatin is a cytokine that directly induces muscle atrophy, and previous studies rodent models and patients have demonstrated an upregulation of myostatin after ACL tear. Using a preclinical rat model, our objective was to determine if the use of a bioneutralizing antibody against myostatin could prevent muscle atrophy and weakness after ACL tear. Rats underwent a surgically induced ACL tear and were treated with either a bioneutralizing antibody against myostatin (10B3, GlaxoSmithKline) or a sham antibody (E1‐82.15, GlaxoSmithKline). Muscles were harvested at either 7 or 21 days after induction of a tear to measure changes in contractile function, fiber size, and genes involved in muscle atrophy and hypertrophy. These time points were selected to evaluate early and later changes in muscle structure and function. Compared to the sham antibody group, 7 days after ACL tear, myostatin inhibition reduced the expression of proteolytic genes and induced the expression of hypertrophy genes. These early changes in gene expression lead to a 22% increase in muscle fiber cross‐sectional area and a 10% improvement in maximum isometric force production that were observed 21 days after ACL tear. Overall, myostatin inhibition lead to several favorable, although modest, changes in molecular biomarkers of muscle regeneration and reduced muscle atrophy and weakness following ACL tear. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2499–2505, 2017
Stimuli‐Responsive Core Multishell Dendritic Nanocarriers
Authors: Mohammadifar Ehsan , Adeli Mohsen , Kharat Ali Nemati , Namazi Hassan , Haag Rainer 
Published: February 2017

Multidomain polymeric nanoparticles containing different blocks with different properties have gained great interest for a wide range of applications in the past two decades. In this work, core multishell (CMS) structures consisting of hyperbranched polyglycerol as core and polylactide and polycaprolactone as shell structures are presented. Number of arms and thickness of shells have been manipulated by precise control over the molar ratios of monomer to terminal functional groups in the reaction feed. The ability of CMS to load and release small guest molecules and also the loading capacities are studied using Rose Bengal as a model dye. Loading capacity of CMS depends on molecular weight, type, and thickness of shells. Due to the difference in polarity and solubility of different blocks, the CMS nanocarriers show medium‐responsive behavior whereupon the encapsulated guest molecules are released in a controlled manner.
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