bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimally invasive guidewireless, navigated pedicle screw placement: a technical report and case series
Authors: Smith Brandon W. , Joseph Jacob R. , Kirsch Michael , Strasser Mary Oakley , Smith Jacob , Park Paul 
Published: August 2017

OBJECTIVEPercutaneous pedicle screw insertion (PPSI) is a mainstay of minimally invasive spinal surgery. Traditionally, PPSI is a fluoroscopy-guided, multistep process involving traversing the pedicle with a Jamshidi needle, placement of a Kirschner wire (K-wire), placement of a soft-tissue dilator, pedicle tract tapping, and screw insertion over the K-wire. This study evaluates the accuracy and safety of PPSI with a simplified 2-step process using a navigated awl-tap followed by navigated screw insertion without use of a K-wire or fluoroscopy.METHODSPatients undergoing PPSI utilizing the K-wire–less technique were identified. Data were extracted from the electronic medical record. Complications associated with screw placement were recorded. Postoperative radiographs as well as CT were evaluated for accuracy of pedicle screw placement.RESULTSThirty-six patients (18 male and 18 female) were included. The patients’ mean age was 60.4 years (range 23.8–78.4 years), and their mean body mass index was 28.5 kg/m2 (range 20.8–40.1 kg/m2). A total of 238 pedicle screws were placed. A mean of 6.6 pedicle screws (range 4–14) were placed over a mean of 2.61 levels (range 1–7). No pedicle breaches were identified on review of postoperative radiographs. In a subgroup analysis of the 25 cases (69%) in which CT scans were performed, 173 screws were assessed; 170 (98.3%) were found to be completely within the pedicle, and 3 (1.7%) demonstrated medial breaches of less than 2 mm (Grade B). There were no complications related to PPSI in this cohort.CONCLUSIONSThis streamlined 2-step K-wire–less, navigated PPSI appears safe and accurate and avoids the need for radiation exposure to surgeon and staff.
Impact of initial medication non-adherence on use of healthcare services and sick leave: a longitudinal study in a large primary care cohort in Spain
Authors: Aznar-Lou Ignacio , Fernández Ana , Gil-Girbau Montserrat , Sabés-Figuera Ramón , Fajó-Pascual Marta , Peñarrubia-María María Teresa , Serrano-Blanco Antoni , Moreno-Peral Patricia , Sánchez-Niubó Albert , March-Pujol Marian , Rubio-Valera Maria 
Published: August 2017

BackgroundInitial medication non-adherence is highly prevalent in primary care but no previous studies have evaluated its impact on the use of healthcare services and/or days on sick leave.AimTo estimate the impact of initial medication non-adherence on the use of healthcare services, days of sick leave, and costs overall and in specific medication groups.Design and settingA 3-year longitudinal register-based study of all primary care patients (a cohort of 1.7 million) who were prescribed a new medication in Catalonia (Spain) in 2012.MethodThirteen of the most prescribed and/or costly medication subgroups were considered. All medication and medication subgroups (chronic, analgesics, and penicillin) were analysed. The number of healthcare services used and days on sick leave were considered. Multilevel multivariate linear regression was used. Three levels were included: patient, GP, and primary care centre.ResultsInitially adherent patients made more use of medicines and some healthcare services than non-adherent and partially adherent patients. They had lower productivity losses, producing a net economic return, especially when drugs for acute diseases (such as penicillins) were considered. Initial medication non-adherence resulted in a higher economic burden to the system in the short term.ConclusionInitial medication non-adherence seems to have a short-term impact on productivity losses and costs. The clinical consequences and long-term economic consequences of initial medication non-adherence need to be assessed. Interventions to promote initial medication adherence in primary care may reduce costs and improve health outcomes.
Effects of nandrolone decanoate on time to consolidation of bone defects resulting from osteotomy for tibial tuberosity advancement
Authors: Ibañez José , Freitas Itallo , Hespanha Ana , Monteiro Juliana , Eggert Mayara , Becker Amanda , Marques Danilo 
Published: August 2017

SummaryStudy design: Experimental study.Objective: The aim of this study was to evaluate the effect of nandrolone decanoate (ND) on the time taken for bone consolidation in dogs undergoing tibial tuberosity advancement surgery (TTA).Materials and methods: Seventeen dogs that underwent TTA surgery were randomly divided into two groups: group C (TTA; 9 stifles), and group TTA+ND (TTA and systemic administration of ND; 8 stifles). Three observers (two radiologists and an orthopaedic surgeon), assessed bone consolidation by visual inspection of serial radiographs at intervals of 21 days following surgery.Results: There were no differences in median weight and age between groups, nor between the medians of the variables right and left stifle. Only weight and age values were normally distributed. The other variables, right and left stifle and time to consolidation, showed non-normal distribution. Meniscal injury was present in all animals in group C and all animals in group TTA+ND. There was a significant difference between time to consolidation in groups C and TTA+ND (p <0.05). One animal in the group TTA+ND showed increased libido. Kappa agreement among observers on radiographs was 0.87.Conclusion: Administration of ND reduces time to bone consolidation in dogs undergoing TTA.Supplementary Material for this article is available online at https://doi.org/10.3415/VCOT-16-09-0130
Efficacy of an oral nutraceutical for the treatment of canine osteo arthritis
Authors: Evans Richard , Conzemius Michael , Scott Ruth 
Published: August 2017

SummaryObjectives: To assess the safety and efficacy of an orally administered nutraceutical (Glu/ CS+; + for additional ingredient) for the treatment of clinical osteoarthritis (OA) in dogs.Methods: In this double-blind, randomized, placebo-controlled clinical trial, client-owned dogs with clinical signs of OA in one or more joints were assigned to a Glu/CS+ (n = 30) or placebo (n = 30) group. Dogs were administered Glu/CS+ or placebo orally and wore an activity monitor (AM) continuously throughout a 97 day study period. Prior to the initiation of the treatment, seven days of baseline activity was collected. On days –7, 30, 60 and 90 of the study, owners completed a patient assessment form (Canine Brief Pain Inventory). Data between groups were compared.Results: No serious adverse events were reported. No difference was found between groups when evaluating daily activity counts during the seven-day pre-treatment period and the 90-day treatment period. Owner assessment (pain interference and pain severity scores) improved over the 90-day treatment period for both groups, however no difference was found between treatment groups. Conclusions: Treatment with oral Glu/CS+ for a 90 day treatment period when compared to placebo treatment did not result in a significant increase in activity counts in dogs with clinical OA. However, owner assessment scores similarly improved throughout the study period for dogs in both groups, suggesting a caregiver placebo effect in this outcome measure.Supplementary material for this article is available at https://doi.org/10.3415/VCOT-17-02-0020
Detection of Water Vapor in the Thermal Spectrum of the Non-transiting Hot Jupiter Upsilon Andromedae b
Authors: Piskorz Danielle , Benneke Björn , Crockett Nathan R. , Lockwood Alexandra C. , Blake Geoffrey A. , Barman Travis S. , Bender Chad F. , Carr John S. , Johnson John A. 
Published: August 2017

Abstract
The Upsilon Andromedae system was the first multi-planet system discovered orbiting a main-sequence star. We describe the detection of water vapor in the atmosphere of the innermost non-transiting gas giant ups And b by treating the star–planet system as a spectroscopic binary with high-resolution, ground-based spectroscopy. We resolve the signal of the planet’s motion and break the mass-inclination degeneracy for this non-transiting planet via deep combined flux observations of the star and the planet. In total, seven epochs of Keck NIRSPEC L band observations, three epochs of Keck NIRSPEC short-wavelength K band observations, and three epochs of Keck NIRSPEC long wavelength K band observations of the ups And system were obtained. We perform a multi-epoch cross-correlation of the full data set with an atmospheric model. We measure the radial projection of the Keplerian velocity (K
P = 55 ± 9 km s−1), true mass (

M
J), and orbital inclination (i
b 24° ± 4°), and determine that the planet’s opacity structure is dominated by water vapor at the probed wavelengths. Dynamical simulations of the planets in the ups And system with these orbital elements for ups And b show that stable, long-term (100 Myr) orbital configurations exist. These measurements will inform future studies of the stability and evolution of the ups And system, as well as the atmospheric structure and composition of the hot Jupiter.
Giardia intestinalis infection associated with malnutrition in children living in northeastern Brazil
Authors: Coronato-Nunes Beatriz , Calegar Deiviane Aparecida , Monteiro Kerla Joeline Lima , Hubert-Jaeger Lauren , Reis Elis Regina Chaves , Xavier Samanta Cristina das Chagas , Carpp Lindsay Nicole , Lima Marli Maria , Bóia Márcio Neves , Carvalho-Costa Filipe Anibal 
Published: August 2017

Introduction: The present study aimed to determine the prevalence and factors associated with Giardia intestinalis infection, verifying its impact on the nutritional status of children in northeastern Brazil.
Methodology: A cross-sectional study was conducted to obtain parasitological, sociodemographic, and anthropometric data in two municipalities in the states of Piauí and Ceará, northeastern Brazil.
Results: Prevalence of giardiasis was 55/511 (10.8%). G. intestinalis was more frequent in people living in poverty (30/209 [14.4%], p = 0.041), performing open evacuation (26/173 [15%], p = 0.034), and drinking rainwater stored in cisterns (9/56 [16.1%], p = 0.005). The proportion of stunting and being underweight in children infected with G. intestinalis was significantly higher than that in uninfected children (5/23 [21.7%] vs. 10/179 [5.6%], p = 0.017, OR = 4.69, 95% confidence interval [CI] = 1.44–15.25 and 5/23 [21.7%] vs. 13/179 [7.3%], p = 0.038, OR = 3.54, 95% CI = 1.13–11.09, respectively). Infection with G. intestinalis remained significantly associated with stunting and being underweight after adjustment for poverty, municipality, sex, and age in a logistic regression multivariate model.
Conclusions: In rural areas in northeastern Brazil, giardiasis has acquired great public health importance in the soil-transmitted helminths control era, impacting the nutritional status of children and requiring new approaches to diagnosis and treatment and translational research that could generate applicable solutions at the community level.
Toward the Development of a Core Set of Outcome Domains to Assess Shared Decision-making Interventions in Rheumatology: Results from an OMERACT Delphi Survey and Consensus Meeting
Authors: Toupin-April Karine , Barton Jennifer , Fraenkel Liana , Li Linda C. , Brooks Peter , De Wit Maarten , Stacey Dawn , Légaré France , Meara Alexa , Shea Beverley , Lyddiatt Anne , Hofstetter Cathie , Gossec Laure , Christensen Robin , Scholte-Voshaar Marieke , Suarez-Almazor Maria E. , Boonen Annelies , Meade Tanya , March Lyn , Pohl Christoph , Jull Janet Elizabeth , Sivarajah Sigogini , Campbell Willemina , Alten Rieke , Karuranga Suvi , Morgan Esi , Kaufman Jessica , Hill Sophie , Maxwell Lara J. , Welch Vivian , Beaton Dorcas , El-Miedany Yasser , Tugwell Peter S. 
Published: August 2017

Objective.The aim of this Outcome Measures in Rheumatology (OMERACT) Working Group was to determine the core set of outcome domains and subdomains for measuring the effectiveness of shared decision-making (SDM) interventions in rheumatology clinical trials.Methods.Following the OMERACT Filter 2.0, and based on a previous literature review of SDM outcome domains and a nominal group process at OMERACT 2014, (1) an online Delphi survey was conducted to gather feedback on the draft core set and refine its domains and subdomains, and (2) a workshop was held at the OMERACT 2016 meeting to gain consensus on the draft core set.Results.A total of 170 participants completed Round 1 of the Delphi survey, and 116 completed Round 2. Respondents came from 29 countries, with 49% being patients/caregivers. Results showed that 14 out of the 17 subdomains within the 7 domains exceeded the 70% criterion (endorsement ranged from 83% to 100% of respondents). At OMERACT 2016, only 8% of the 96 attendees were patients/caregivers. Despite initial votes of support in breakout groups, there was insufficient comfort about the conceptualization of these 7 domains and 17 subdomains for these to be endorsed at OMERACT 2016 (endorsement ranged from 17% to 68% of participants).Conclusion.Differences between the Delphi survey and consensus meeting may be explained by the manner in which the outcomes were presented, variations in participant characteristics, and the context of voting. Further efforts are needed to address the limited understanding of SDM and its outcomes among OMERACT participants.
Les experts des comités d’entreprise en France : une coopération originale avec les représentants des salariés
Authors: Capron Michel 
Published: August 2017

L’assistance des experts-comptables auprès des comités d’entreprise en France offre un exemple de relation originale de coopération entre des experts et des représentants de salariés, majoritairement élus sur des listes syndicales. Le contexte institutionnel et historique a largement déterminé le rôle économique que les comités d’entreprise ont joué depuis leur création, il y a une cinquantaine d’années. Les experts ont adapté et fait évoluer leur offre de prestation à une demande protéiforme et souvent indéterminée ; elle s’est notamment élargie à l’initiative des experts, sous l’effet des mutations économiques et sociales des années 1970. Consacrée par la législation en 1982, la place des experts dans les relations sociales contribue à l’institutionnalisation de la représentation salariale dans l’entreprise.
HIV-1 Infection Is Associated with Depletion and Functional Impairment of Mycobacterium tuberculosis–Specific CD4 T Cells in Individuals with Latent Tuberculosis Infection
Authors: Day Cheryl L. , Abrahams Deborah A. , Harris Levelle D. , van Rooyen Michele , Stone Lynnett , de Kock Marwou , Hanekom Willem A. 
Published: August 2017

Abstract
Coinfection with HIV is the single greatest risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis disease. HIV-associated dysregulation of adaptive immunity by depletion of CD4 Th cells most likely contributes to loss of immune control of LTBI in HIV-infected individuals, although the precise mechanisms whereby HIV infection impedes successful T cell–mediated control of M. tuberculosis have not been well defined. To further delineate mechanisms whereby HIV impairs protective immunity to M. tuberculosis, we evaluated the frequency, phenotype, and functional capacity of M. tuberculosis-specific CD4 T cells in HIV-infected and HIV-uninfected adults with LTBI. HIV infection was associated with a lower total frequency of cytokine-producing M. tuberculosis-specific CD4 T cells, and preferential depletion of a discrete subset of M. tuberculosis-specific IFN-γ+IL-2−TNF-α+ CD4 T cells. M. tuberculosis-specific CD4 T cells in HIV-infected individuals expressed significantly higher levels of Ki67, compared with HIV-uninfected individuals, thus indicating recent activation and turnover of these cells in vivo. The ex vivo proliferative capacity of M. tuberculosis-specific CD4 T cells was markedly impaired in HIV-infected individuals, compared with HIV-uninfected individuals. Moreover, HIV infection was associated with increased M. tuberculosis Ag-induced CD4 T cell death ex vivo, indicating a possible mechanism contributing to impaired proliferative capacity of M. tuberculosis-specific CD4 T cells in HIV-infected individuals. These data provide new insights into the parameters of M. tuberculosis-specific CD4 T cell immunity that are impaired in HIV-infected individuals with LTBI, which may contribute to their increased risk of developing active tuberculosis disease.
FRADKIN, Raúl (org.). La ley es tela de araña. Ley, justicia y sociedad rural en Buenos Aires, 1780 – 1830. Buenos Aires: Prometeo libros, 2009, 204p
Authors: Dallanora Cristina 
Published: August 2017

http://dx.doi.org/10.5007/1984-9222.2015v7n13p299 La ley es tela de araña: experiências da lei e da justiça dos camponeses de Buenos Aires
SOUZA, Davisson Cangussu. Sindicalismo e desempregados: um estudo comparativo das centrais sindicais do Brasil e da Argentina (1990-2002). Belo Horizonte: Fino Traço Editora, Coleção Trabalho e Desigualdade, 2013, 384 p.
Authors: Pérez Álvarez Gonzalo 
Published: August 2017

http://dx.doi.org/10.5007/1984-9222.2015v7n13p303 A relação entre os sindicatos e os trabalhadores desempregados: um desafio central para a organização da classe operária
Espécies de plantas visitadas por Heliactin bilophus (Aves, Trochilidae) na Chapada dos Veadeiros, durante a estação chuvosa
Authors: Ghiringhello Gabriel Baruffaldi , Tubelis Dárius Pukenis 
Published: August 2017

http://dx.doi.org/10.5007/2175-7925.2009v22n4p139 Os hábitos alimentares do beija-flor Heliactin bilophus ainda são pouco conhecidos. Este trabalho teve como objetivo identificar as espécies de plantas mais visitadas por H. bilophus com finalidades de alimentação (consumo de néctar) durante a estação chuvosa no Parque Nacional da Chapada dos Veadeiros, em Goiás. as observações foram realizadas em duas estações chuvosas (janeiro de 2006 e fevereiro de 2008). A metodologia baseou-se em percorrer trilhas em duas áreas de campo sujo e em duas de campo rupestre. Todo registro de um indivíduo consumindo néctar de uma planta em flor foi considerado como uma visita. Foram observadas 296 visitas, compreendendo oito espécies de plantas dos estratos arbustivo e herbáceo. as espécies mais frequentemente visitadas foram Bauhinia tenella (Caesalpinoideae) e Vochysia pumila (Vochysiaceae) em campo sujo, e Lychnophora ericoides (asteraceae), em campo rupestre. Essas três espécies foram comumente encontradas nos locais de estudo. Nas duas fisionomias, Heliactin bilophus consumiu néctar de poucas espécies de plantas. as espécies mais frequentemente visitadas apresentavam flores em abundância.
Cidades médias e a atração de migrantes qualificados
Authors: Barbosa Adriana Mota , Matos Ralfo  Edmundo Da Silva , Lobo Carlos Fernando Ferreira 
Published: August 2017

A reflexão e pesquisa investigam como o Estado tem atuado no território enquanto fomentador de políticas de formação, qualificação e requalificação da força de trabalho e discutem as relações que se estabelecem com o desenvolvimento econômico e demográfico. O estudo resgata as metamorfoses do conceito de cidade média e o papel da migração no dinamismo econômico e demográfico destas localidades. Com o respaldo da pesquisa bibliográfica e em consonância com a metodologia adotada, foram selecionados os municípios mineiros de porte médio, com sede de Instituto Federal e crescimento demográfico e da renda no período de 2000 a 2010 e feitas comparações com os demais municípios, de mesmo porte que não possuem um Instituto Federal. A averiguação empírica é confrontada com o referencial teórico construído a fim de inferir a validade da hipótese levantada e as conclusões gerais atestam a comprovação da mesma.
Editorial: Psicología y Feminismo - Cuestiones epistemológicas y metodológicas
Authors: Reyes Espejo María Isabel , Mayorga Claudia , Araújo Menezes Jaileila de 
Published: August 2017

La relación entre psicología y feminismo ha sido persistente, continua y productiva en el tiempo, a pesar de tomar formas contingentes, histórica y geográficamente. El cuestionamiento a los modos en que asumimos y entendemos la construcción de la realidad -y de lo que aceptamos o descalificamos como conocimiento- demanda la consideración de la ética como una dimensión que no puede estar ajena a los intereses individuales y sociales. La problematización asociada la dicotomía de lo público y privado permite visibilizar, por ejemplo, cómo -y pese a las denuncias progresivas en el devenir de los años- todavía el ingreso de las mujeres al espacio público está lejos de inscribirse de manera completa. La escasa reflexión moral y política en cuestiones como la división del trabajo por género al interior de las familias, así como las preocupaciones de las mujeres siguen permaneciendo invisibles en las teorías contemporáneas de justicia y comunidad.
GNAQPMS v1.1: accelerating the Global Nested Air Quality Prediction Modeling System (GNAQPMS) on Intel Xeon Phi processors
Authors: Wang Hui , Chen Huansheng , Wu Qizhong , Lin Junmin , Chen Xueshun , Xie Xinwei , Wang Rongrong , Tang Xiao , Wang Zifa 
Published: August 2017

Abstract. The Global Nested Air Quality Prediction Modeling System (GNAQPMS) is the global version of the Nested Air Quality Prediction Modeling System (NAQPMS), which is a multi-scale chemical transport model used for air quality forecast and atmospheric environmental research. In this study, we present the porting and optimisation of GNAQPMS on a second-generation Intel Xeon Phi processor, codenamed Knights Landing (KNL). Compared with the first-generation Xeon Phi coprocessor (codenamed Knights Corner, KNC), KNL has many new hardware features such as a bootable processor, high-performance in-package memory and ISA compatibility with Intel Xeon processors. In particular, we describe the five optimisations we applied to the key modules of GNAQPMS, including the CBM-Z gas-phase chemistry, advection, convection and wet deposition modules. These optimisations work well on both the KNL 7250 processor and the Intel Xeon E5-2697 V4 processor. They include (1) updating the pure Message Passing Interface (MPI) parallel mode to the hybrid parallel mode with MPI and OpenMP in the emission, advection, convection and gas-phase chemistry modules; (2) fully employing the 512 bit wide vector processing units (VPUs) on the KNL platform; (3) reducing unnecessary memory access to improve cache efficiency; (4) reducing the thread local storage (TLS) in the CBM-Z gas-phase chemistry module to improve its OpenMP performance; and (5) changing the global communication from writing/reading interface files to MPI functions to improve the performance and the parallel scalability. These optimisations greatly improved the GNAQPMS performance. The same optimisations also work well for the Intel Xeon Broadwell processor, specifically E5-2697 v4. Compared with the baseline version of GNAQPMS, the optimised version was 3.51 × faster on KNL and 2.77 × faster on the CPU. Moreover, the optimised version ran at 26 % lower average power on KNL than on the CPU. With the combined performance and energy improvement, the KNL platform was 37.5 % more efficient on power consumption compared with the CPU platform. The optimisations also enabled much further parallel scalability on both the CPU cluster and the KNL cluster scaled to 40 CPU nodes and 30 KNL nodes, with a parallel efficiency of 70.4 and 42.2 %, respectively.