bluuebunny/crossref_metadata_2025_split huggingface dataset:
Galectin-3 expression in colorectal cancer and its correlation with clinical pathological characteristics and prognosis
Authors: Tao Liu , Jin Li , Dechun Li , Hongqiang Yang , Changhua Kou , Guijun Lei 
Published: July 2017

Abstract

Objective
To explore the expression levels of galectin-3 in colorectal cancer and the association between galectin-3 and its clinical pathological parameters, as well as the prognosis of colorectal cancer patients.

Methods
An immunohistochemistry assay was used to test the expression levels of galectin-3 in cancer tissues of 61 colorectal cancer cases and in normal intestinal tissues adjacent to the cancer tissues of 23 cases. The associations between protein expression levels of galectin-3 and the clinicopathological features, such as age, sex, pathology type, lymphatic metastasis, and prognosis were also analyzed.

Results
The positive rate of galectin-3 in cancer tissues was significantly higher than that of cancer-adjacent tissues: 62.5% (38/61) versus 13.0% (3/23) (P<0.05), respectively. Correlation was found between the protein expression of galectin-3 and the tumor size (P<0.05), as well as between the tumor differentiation (P<0.05) and Duke staging (P<0.05). The median progression-free survival times of patients with galectin-3 positive and negative expression were 19.2 and 35.1 months, respectively, with significant statistical difference (P<0.05).

Conclusion
Galectin-3 expression was correlated with the genesis and development of colorectal cancer and which could be used a biological marker for the prognosis of colorectal cancer patients.
Das „Altwerden funktionaler Differenzierung“ und die „nächste Gesellschaft“
Authors: Lehmann Maren 
Published: July 2017

ZusammenfassungDer vorliegende Text diskutiert die Möglichkeit, dass die funktional differenzierte Gesellschaft eine (sehr alte) variantenreiche Gleichzeitigkeit sozialer Ordnungen ist und sich selbst als Gesellschaft im Sinne einer Ökologie von Verfallserfahrungen und Fortschrittserwartungen, einer Ressource formaler Organisation und eines medialen Netzes beschreibt. Gefragt wird danach, ob der Primat funktionaler Differenzierung, der diese Formvarianten ermöglicht, nochmals wechseln kann und ob das zur Folge hätte, dass diese Gesellschaft durch eine ‚nächste Gesellschaft‘ abgelöst würde.
Modelling of Electrodynamic Phenomena in Slowly Moving Media
Authors: Rozov Andrey Leonidovich 
Published: July 2017

Abstract
We discuss the feasibility of using, along with Minkowski equations obtained on the basis of the theory of relativity and used at present in electrodynamics, alternative methods of describing the processes of interaction between electromagnetic fields and moving media. In this article, a way of describing electromagnetic fields in terms of classical mechanics is offered. A system of electrodynamic equations for slowly moving media was derived on the basis of Maxwell’s theory within the framework of classical mechanics using Wilsons’ experimental data with dielectrics in a previous article [A. Rozov, Z. Naturforsch. 70, 1019 (2015)]. This article puts forward a physical model that explains the features of the derived equations. The offered model made it possible to suggest a new approach to the derivation of electrodynamic equations for slowly moving media. A variant of Galileo’s relativity principle, in accordance with which the electrodynamic equations for slowly moving media should be considered as Galilean-invariant, is laid down on the basis of both the interpretation of Galileo’s concept following from Galileo’s works and Pauli’s concept of postulate of relativity within the framework of the represented physical model.
Zero-Time Tunneling – Revisited
Authors: Nimtz Günter , Aichmann Horst 
Published: July 2017

Abstract
Since 1931, the nonclassical process of tunneling was conjectured to have a zero-time delay in the barrier. These theories have been rejected and denied. However, photonic and recent electronic tunneling experiments have proven the zero-time prediction. Tunneling is due to virtual wave packets in electromagnetic, elastic, and Schrödinger wave fields up to the macroscopic level. In this article we cite theoretical and experimental studies on zero-time tunneling, which have proven this striking behavior.
Anatomia do lenho carbonizado de 10 espécies nativas da Planície Costeira do Rio Grande do Sul – Subsídio a pesquisas arqueobotânicas e paleoecológicas
Authors: Ávila André , Giongo Claudia , Scheel-Ybert Rita 
Published: July 2017

RESUMO:
Antracologia é o estudo do carvão arqueológico ou de origem sedimentar a partir da anatomia do lenho. Uma correta identificação depende de um bom conhecimento da anatomia do lenho e de material de referência adequado. Neste artigo descrevemos a anatomia do carvão de dez espécies nativas que ocorrem na Planície Costeira do Rio Grande do Sul – Lithraea brasiliensis, Schinus polygamus (Anacardiaceae), Ilex dumosa (Aquifoliaceae), Ocotea pulchella (Lauraceae), Myrcia palustris, Myrrhinium atropurpureum (Myrtaceae), Guapira opposita (Nyctaginaceae), Randia ferox (Rubiaceae), Casearia sylvestris (Salicaceae) e Chrysophyllum marginatum (Sapotaceae). A estrutura anatômica da madeira se preservou perfeitamente após carbonização, apesar de ter ocorrido redução de massa e contração anisotrópica. As pequenas variações induzidas por estes fenômenos não interferem na qualidade do carvão nem no potencial de identificação dos taxa. Os resultados obtidos corroboram a viabilidade da identificação taxonômica a partir da anatomia do carvão.
ABSTRACT:
Anthracology is the study of charcoal from archaeological or sedimentary contexts based on wood anatomy. A proper identification depends on a good knowledge of charcoal anatomy as well as on the availability of appropriate reference material. In this paper we describe the charcoal anatomy of ten woody species that occur at Rio Grande do Sul Coastal Plain (Southern Brazil) – Lithraea brasiliensis, Schinus polygamus (Anacardiaceae), Ilex dumosa (Aquifoliaceae), Ocotea pulchella (Lauraceae), Myrcia palustris, Myrrhinium atropurpureum (Myrtaceae), Guapira opposita (Nyctaginaceae), Randia ferox (Rubiaceae), Casearia sylvestris (Salicaceae) and Chrysophyllum marginatum (Sapotaceae). The wood anatomical structure was perfectly preserved after carbonization, despite mass loss and anisotropic shrinkage. The small variations due to these properties do not affect charcoal quality nor its identification potential. The results here obtained attest of the reliability of taxonomic identification from charcoal anatomy.
Maternal and female fetal testosterone levels are associated with maternal age and gestational weight gain
Authors: Kallak Theodora Kunovac , Hellgren Charlotte , Skalkidou Alkistis , Sandelin-Francke Lotta , Ubhayasekhera Kumari , Bergquist Jonas , Axelsson Ove , Comasco Erika , Campbell Rebecca E , Sundström Poromaa Inger 
Published: July 2017

ObjectivePrenatal androgen exposure has been suggested to play a role in polycystic ovary syndrome. Given the limited information on what maternal characteristics influence maternal testosterone levels, and the even less explored routes by which female fetus androgen exposure would occur, the aim of this study was to investigate the impact of maternal age, BMI, weight gain, depressed mood and aromatase SNPs on testosterone levels in maternal serum and amniotic fluid of female fetuses.MethodsBlood samples from pregnant women (n = 216) obtained in gestational weeks 35–39, and pre-labor amniotic fluid samples from female fetuses (n = 56), taken at planned Caesarean section or in conjunction with amniotomy for induction of labor, were analyzed. Maternal serum testosterone and amniotic fluid testosterone and cortisol were measured by tandem mass spectrometry.ResultsMultiparity (β = −0.28,P < 0.001), self-rated depression (β = 0.26,P < 0.001) and weight gain (β = 0.18,P < 0.05) were independent explanatory factors for the maternal total testosterone levels. Maternal age (β = −0.34,P < 0.001), weight gain (β = 0.19,P < 0.05) and amniotic fluid cortisol levels (β = 0.44,P < 0.001) were independent explanatory factors of amniotic fluid testosterone in female fetuses, explaining 64.3% of the variability in amniotic fluid testosterone.Wider implications of the findingsYoung maternal age and excessive maternal weight gain may increase the prenatal androgen exposure of female fetuses. Further studies are needed to explore this finding.
Indoor air quality measurements in Hungarian residential buildings
Authors: Lipták-Váradi Julianna 
Published: July 2017

Indoor air quality is a major part of indoor environmental quality and plays an important role in creating sustainable and healthy indoor environments. Well-being, health and comfort are affected by indoor air quality. The measurements that are introduced in this research paper were used to record the results of three different residential interiors. These data are a part of a larger scale research project that included the evaluation of residential buildings, offices, university interiors and for instance nurseries. The reason behind conducting the measurements in these interiors was that in all of the examples inadequate indoor air quality and therefore human discomfort, illness and also building failure occurred.
In this paper the theoretical background of the research and the measurement of indoor air quality (indoor air temperature, relative humidity level and carbon dioxide level) will be introduced. The poor indoor air quality in these buildings is a result of a complex system. The thermal bridges of the facade cause cold interior surfaces, the airtight solutions cause high relative humidity levels. These two combined result in mould appearance. Besides, the lack of appropriate ventilation rate can be the third part of the reason behind poor indoor air quality.
Based on the results of the measurement data, different solutions are suggested in each case to improve indoor environmental and air quality, in accordance with creating healthier indoor environments.
Analysis of flow and sedimentation processes in secondary sedimentation tank
Authors: Hrudka Jaroslav , Stanko Štefan , Holubec Michal 
Published: July 2017

In the process of design and operation of sewerage system are used empirical formulas, which are in many cases, become obsolete and unusable when somebody can use nowadays modern technologies and materials. Therefore there is the possibility of using the mathematical models enormous importance for the enhanced environmental protection with the lowest operating and investment costs. In this modern method of analyzing of sewers has been designated as the first object, the object sedimentation tank. The purpose of the primary and secondary settling tank is to ensure the reduction of concentration the floating solids.
For the solution of research work has been chosen, after consultations with representatives of the Western Slovakia Water Company as interesting object of sedimentation tank located on the waste water treatment plant Nitra - Dolné Krškany.
Measurements on the object settlement tank situated at waste water treatment plant Nitra confirmed the expected speed parameters of the sewage in the tank. The velocity of wastewater is in the most cases very low, and even insignificant. However, finding that the sludge cloud has a non-standard form of a double wave gives the opportunity to optimize the operation of facilities sedimentation tank. The measured parameters are used as calibration parameters to input to the mathematical simulations, which are created by software ANSYS fluent.
Bioaktivitas Ekstrak Kasar Aseton, Fraksi, dan Subfraksinya dari Ulva fasciata Terhadap Sel Lestari Tumor Hela
Authors: Wikanta Thamrin , Prabukusuma Andika , Ratih Dian , Januar Hedi Indra 
Published: July 2017

Telah dilakukan pengujian bioaktivitas ekstrak kasar aseton, fraksi, dan subfraksinya dari Ulva fasciata terhadap sel lestari tumor HeLa. U. fasciata dimaserasi dalam aseton lalu ekstrak disaring dan pelarut dievaporasi. Hasil uji fitokimia menunjukkan bahwa ekstrak kasar aseton U. fasciata mengandung golongan senyawa flavonoid, steroid, dan saponin. Ekstrak kasar tersebut memiliki aktivitas antioksidan (IC50 = 411,81 mg/mL) lebih rendah dibandingkan vitamin C sebagai control (IC50 = 5,01 mg/mL). Ekstrak kasar aseton dipartisi menggunakan heksan, etil asetat, dan metanol-air. Hasil uji toksisitas terhadap Artemia salinamenunjukkan nilai LC50 dari ekstrak kasar aseton, fraksi heksan, fraksi etil asetat, dan fraksi metanol-air masing-masing sebesar 103,86; 128,03; 63,07; dan 406,05 mg/mL. Hasil uji sitotoksisitas terhadap sel lestari tumor HeLa menunjukkan nilai IC50 dari ekstrak kasar aseton, fraksi heksan, fraksi etil asetat, dan fraksi metanol-air masing-masing sebesar 62,86; 43,56; 18,85; dan 37,56 mg/mL. Fraksi etil asetat yang memiliki sitotoksisitas tertinggi kemudian difraksinasi melalui kolom khromatografi Sepra C-18 dengan elusi gradien polaritas menghasilkan 6 subfraksi. Hasil uji sitotoksisitas masing-masing subfraksi terhadap sel lestari tumor HeLa pada konsentrasi 19 mg/mL menunjukkan nilai inhibisi: subfraksi-1 negatif (non-aktif); subfraksi-2 > 100% (sitotoksik); subfraksi-3 > 100% (sitotoksik); subfraksi-4 > 100% (sitotoksik); subfraksi-5 < 50% (non-aktif); dan subfraksi-6 = 100% (sitostatik).
Perfil eletrocardiográfico de ratos com escoliose induzida por colete de PVC
Authors: Pezolato Vítor Alexandre , Christofoletti Daiane Cristina , Abreu Marcos Fabio Ribeiro de , Chingui Luciano Júlio , Da Silva Carlos Alberto 
Published: July 2017

A escoliose é caracterizada por alterações anatomo-fisiológicas importantes. Diversos pesquisadores têm se dedicado ao estudo dos comprometimentos gerados pela escoliose, a maioria dos estudos com animais envolve utilização de modelos invasivos para indução de escoliose. O objetivo do trabalho foi avaliar se o modelo não invasivo de indução de escoliose em ratos promove modificações na funcionalidade cardíaca. Métodos: Ratos Wistar foram divididos em 2 grupos (n=8): Controle (C), escoliótico (E). Os animais do grupo escoliótico foram submetidos à utilização de um colete de PVC durante 12 semanas consecutivas para a indução da escoliose. Após, foram avaliados os seguintes parâmetros: peso dos animais, FC, SÂQR, intervalo QRS, PA, força de contração na presença de noradrenalina e o padrão dP/dt+. A análise estatística foi feita pelo teste de normalidade (Kolmogorov-Smirnov), ANOVA e post test Tukey (p menor 0,05). Quanto aos resultados, os animais do grupo (E) apresentaram menor peso; não houve diferente da FC entre os grupos; o grupo (E) apresentou desvio de 11º do SÂQRS; a duração da onda R e o intervalo PR; a força de contração e o padrão dP/dt+ não tiveram diferença entre os grupos. Desse modo, os dados sugerem que o modelo não invasivo de indução de escoliose não provoca alterações do padrão fisiológico cardíaco.
Comparison of Endothelial Function in Healthy Patients and Patients With Chronic Periodontitis and Myocardial Infarction
Authors: Punj Anahita , Shenoy Santhosh B. , Subramanyam K. 
Published: July 2017

Background: The inflammatory burden as a result of severe periodontal disease acts as an insult to the endothelium. This disruption in the function of the endothelium predisposes it toward formation of atherosclerotic plaque, which may be a subsequent risk for coronary artery disease. The aim of this study is to estimate and compare endothelial function via flow‐mediated dilation (FMD) assessment in periodontal health and disease.Methods: A total of 120 patients were selected and categorized equally into three groups: 1) healthy (control); 2) chronic periodontitis (CP); and 3) myocardial infarction (MI). Periodontal inflamed surface area (PISA) and FMD were assessed in all patients. Fasting blood samples were collected to estimate lipid profile. Analysis of variance was used for comparison of lipid profile, whereas Kruskal–Wallis test was used for comparison of FMD and PISA scores among the study groups with P <0.05.Results: Comparison of FMD levels among the three groups showed statistically significant difference, with P <0.001. The value was statistically significant when the healthy group was compared with the CP and MI groups but not when the CP group was compared with the MI group. Lipid profile levels were statistically significant on comparison between the healthy and CP groups and between the CP and MI groups.Conclusion: Endothelial function was impaired in patients with CP compared with healthy patients, and the dysfunction observed was similar to that observed in the MI group based on FMD values.
Influence of Implant Neck Surface and Placement Depth on Crestal Bone Changes Around Platform‐Switched Implants: A Clinical and Radiographic Study in Dogs
Authors: Valles Cristina , Rodríguez‐Ciurana Xavier , Nart Jose , Santos Antonio , Galofre Marta , Tarnow Dennis 
Published: July 2017

Background: The aim of this animal study is to analyze bone remodeling around platform‐switching (PS) implants with and without a machined (MACH) collar placed at different levels in relation to the crestal bone in a canine model.Methods: All mandibular premolars and first molars were extracted in five dogs. After 6 months, grit‐blasted acid‐etched (GBAE) PS implants with and without a MACH neck were randomly inserted in each hemimandible, positioning the implant‐abutment interface in either a supracrestal (+1.5 mm), equicrestal, or subcrestal (−1.5 mm) position, and healing abutments were connected. Implant abutments were dis/reconnected at 12, 14, 16, and 18 weeks after implant placement. After 6 months of healing, animals were sacrificed. Clinical parameters and periapical radiographs were registered on the day of implant placement, at 2 months, at every abutment dis/reconnection, and at sacrifice. Crestal bone changes were calculated and defined as the primary outcome variable.Results: When crestal bone changes from implant placement to 6 months were compared between MACH and GBAE groups, no significant differences were encountered except for implants placed in an equicrestal position (P = 0.04). However, multivariable regression analysis revealed no significant differences between MACH and GBAE implants placed in a supracrestal (β = −0.08; P = 0.45), equicrestal (β = −0.05; P = 0.50), or subcrestal (β = −0.13; P = 0.19) position.Conclusion: Surface treatment of the implant neck had no significant influence on crestal bone changes around PS implants with and without a MACH collar.
Kesesuaian Pembangunan Rumah Susun Sederhana Sewa terhadap Standar Perumahan Ideal di Sukoharjo
Authors: Hasanah Isandi Nurul , Rahayu Murtanti Jani , Putri Rufia Andisetyana 
Published: July 2017

<div><p><em>Construction of the rented simple flats is the option of government’s policy to meet the needs of adequate housing for low-income. The rented simple flats in Sukoharjo already inhabited 3 blocks of 6 blocks. The degree of occupancy will indirectly reflect quality the construction of flats. The problem in this study is whether development the rented simple flats in Sukoharjo complies with the standar of ideal housing. The purpose of research is the degree of conformity the rented simple flats in Sukoharjo as the standar of ideal housing. The method is used the deductive research methods with quantitative research. The analysis technique is used the analysis of scoring on any variable of the standards of ideal housing. The conclusions from this research is that there are nine variables known as the factors that influence the development of the rented simple flats in Sukoharjo as the ideal flats. The variables that have been suitable with the standar of ideal housing are the policy, the price of rent and accessibily</em><em>. However, some variables that have not been optimal like</em><em> the </em><em>infrastructures, material contruction and the others</em><em>. Consequently, Sukoharjo’s District Government and some of the parties concerned to repair deficiency and accommodate the needs of the community to achieve development the ideal flats.</em></p><p><em> </em></p><p><strong><em>Keywords</em></strong><em>: Contruction of rented simple flats, standards of ideal housing, scoring analysis</em></p></div>
KESESUAIAN KLASTER INDUSTRI ANYAMAN BAMBU TERHADAP INDIKATOR KEBERLANJUTAN DI DESA WALEN KECAMATAN SIMO KABUPATEN BOYOLALI
Authors: Haji Vicha Ardhea Puspa , Soedwiwahjono Soedwiwahjono , Hardiana Ana 
Published: July 2017

<div><p><strong><em>Abstract:</em></strong><em> Five hamlet in Walen Village, there is<strong> </strong>Pokoh, Wates, Walen, Jeringan and Ngampon are bamboo industry cluster area. This cluster is characterized by the existence of a bamboo forest as a provider of industrial raw materials, the people who have expertise to weave bamboo, bamboo woven activity and presence of a network or cooperation of small industry craftsmen. Industry cluster is absorbing the local workforce so we need to cuntineu in order to trigger the growth of the local economy. The problem in this research is how the level of sustainability of bamboo woven industry cluster in Walen Village to see between the existing conditions with the concept of sustainability of industrial cluster. The purpose of this study is to determine the suitability of Walen Village, Simo, Boyolali with sustainability concept. This study uses deductive research methods with quantitative research. Analysis uses scoring analysis which is based on the normative and suitability to the needs of the community. Conclusions from this research is the suitability of bamboo woven industry cluster Walen Village towards sostainability concept into the category of medium suitability. Normatively, the sustainability factor were classified as high compatibility towards sustainability indicators are infrastructure, raw materials and capital; were classified as moderate suitability factors are location and labor; and were classified as low suitability are market, technology, partnership and government support. The result of analysis based on suitability to community needs were classified as high suitability is the raw material; were classified as moderate suitability are location, infrastructure, market, capital, labor, technology and partnership; and were classified as low suitability is government support.<strong></strong></em></p><p><strong><em> </em></strong></p><p><strong><em>Keywords:</em></strong><em> Industry Cluster, Small Industry, Sustainable Development.</em></p></div>
SOLO CRAFT GALLERY EXPO DENGAN PENDEKATAN ARSITEKTUR JAWA KONTEMPORER
Authors: Bioza Betyona , Pitana Titis Srimuda , Gunawan Gunawan 
Published: July 2017

<p><strong><em>Abstract: </em></strong><em>Solo Craft Gallery Expo is an effort to accommodate the presence of creative industries joined in the craft subsector SMEs, and facilitating MICE activities in the city of Solo. The space is in the form of art galleries as well as a market for good packaging and expo space with diverse capacities. Combining the two functions of this building is a strategy for mutually supporting each other’s existences. Gallery space presented as cultural charms, while the expo space plays a role in bringing visitors. The government policies in synergy with the city’s potential efforts to support and facilitate the development of the city for more advances physical quality and human resources. This system if it is associated with the city of Solo as location, intersects with the image which is the city of culture. This last issue is associated with contemporary architecture, which is an effort to locate and revive the values of cultural and society, as a reflection of the city’s identity. In this case, the Javanese architecture which is the local architecture and result of the Javanese cultural community life, deserve to be appreciated to exist as a force of local architecture. The process of aligning the image of the building with the city image of the building of Solo Craft Gallery Expo, carried out through the application of contemporary Javanese Architecture.</em></p><p><em> </em></p><p><strong><em>Keywords</em></strong><em>: MSME craft’s sub-sector, craft galleries, MICE facilities, contemporary Javanese architecture.</em> <em></em></p>