bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural organization and tooth development in a Homo aff. erectus juvenile mandible from the Early Pleistocene site of Garba IV at Melka Kunture, Ethiopian highlands
Authors: Zanolli Clément , Dean M. Christopher , Assefa Yared , Bayle Priscilla , Braga José , Condemi Silvana , Endalamaw Metasebia , Engda Redae Blade , Macchiarelli Roberto 
Published: November 2016

AbstractObjectivesThe immature partial mandible GAR IVE from the c. 1.7 Ma old Garba IV site at Melka Kunture (Upper Awash Basin, Ethiopia), the earliest human representative from a mountain‐like environment, represents one of the oldest early Homo specimens bearing a mixed dentition. Following its first description (Condemi, ), we extended the analytical and comparative record of this specimen by providing unreported details about its inner morphology, tooth maturational pattern and age at death, crown size, and tooth tissue proportions.Materials and MethodsThe new body of quantitative structural information and virtual imaging derives from a medical CT record performed in 2013.ResultsCompared to the extant human condition and to some fossil representatives of comparable individual age, the GAR IVE mandible reveals absolutely and relatively thick cortical bone. Crown size of the permanent lateral incisor and the canine fit the estimates of H. erectus s.l., while the dm2 and the M1 more closely approach those of H. habilis‐rudolfensis. Molar crown pulp volumes are lower than reported in other fossil specimens and in extant humans. The mineralization sequence of the permanent tooth elements is represented four times in our reference sample of extant immature individuals (N = 795).ConclusionsThe tooth developmental pattern displayed by the immature individual from Garba IV falls within the range of variation of extant human populations and is also comparable with that of other very young early fossil hominins. Taken together, the evidence presented here for mandibular morphology and dental development suggest GAR IVE is a robust 2.5‐ to 3.5‐year old early Homo specimen.
Microstructure and melting behavior of a solution‐cast polylactide stereocomplex: Effect of annealing
Authors: Hu Xiaodan , Shao Jun , Zhou Dongdong , Li Gao , Ding Jianxun , Chen Xuesi 
Published: November 2016

ABSTRACTThe effect of annealing on the microstructure and melting behavior of a solution‐cast polylactide (PLA) stereocomplex (sc) was systematically investigated by differential scanning calorimetry and small‐angle X‐ray scattering. A preorder state, an intermediate form between the amorphous and crystalline states, was found in the solution‐cast poly(l‐lactide)–poly(d‐lactide) blend. When the annealing temperature (Ta) was below 220 °C, a part of the preorder state directly formed thicker sc crystallites; these corresponded to the second melting peak, which appeared around 250 °C during the heating process. Although the rest melted and became the amorphous phase, it formed a thinner lamella under the restriction of the unmelted initial sc crystallites during annealing; the melting process of this lamella was parallel to that of the new melting peak, which appeared around 220 °C. The melting of the initial crystal formed as the solvent volatilized corresponded to the range of the first melting temperature around 230 °C. When Ta was above 220 °C, the preorder state melted completely, and the initial crystal experienced perfection process. Furthermore, the highest melting temperature of PLA sc (254.1 °C, with a fusion enthalpy of 125.5 J/g) was obtained when Ta was 235 °C. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44626.
The role of the school climate in high school students’ mental health and identity formation: A South Australian study
Authors: Riekie Helen , Aldridge Jill M. , Afari Ernest 
Published: November 2016

The well‐documented increase in student mental health issues in Australia and growing recognition of the need for education to play a part in students’ identity formation prompted this study. The research reported in this article sought to identify specific elements of the school climate that were likely to influence the interplay of adolescent health and development and students’ identity formation. The aim was two‐fold. First, the study examined the relationships between students’ perceptions of the school climate and self‐reports of wellbeing, resilience and moral identity; and, second, the interrelationships between the three outcome variables were explored. Two surveys, one to assess students’ perceptions of features of the school climate, and another to assess students’ wellbeing, resilience and moral identity, were administered to 618 Year 11 students from 15 independent schools in South Australia. Structural equation modelling was used to investigate hypothesised relationships between students’ perceptions of their school climate and self‐reports of wellbeing, resilience and moral identity. Our results indicated statistically significant and positive relationships between school‐climate factors and each of the three outcome variables. Further, indirect relationships (mediated largely by resilience) were found between school‐climate factors and students’ wellbeing. Our findings could be used to guide schools in building tangible, purposeful environments that engender well‐balanced, positive, resilient citizens with strong moral identities.
Efficacy and safety of darbepoetin alfa initiated at hemoglobin ≤10 g/dL in patients with stage IV cancer and chemotherapy‐induced anemia
Authors: Boccia Ralph V. , Henry David H. , Belton Laura , Bohac Chet , Ghazal Hassan H. 
Published: November 2016

AbstractData on efficacy and safety of darbepoetin alfa (DA) administered at hemoglobin (Hb) ≤10 g/dL are limited. In this analysis, we examined DA's efficacy and safety in patients with Stage IV cancers and chemotherapy‐induced anemia (CIA) initiated on DA at Hb ≤10 g/dL. Data for patients with Stage IV cancers and CIA and who initiated DA at Hb ≤10 g/dL were extracted from three phase 3 trials identified in a central database of Amgen‐sponsored DA studies in CIA. Efficacy outcomes were assessed by achievement of Hb increases of ≥1 g/dL and ≥2 g/dL and red blood cell (RBC) or whole blood transfusion requirements. Data were analyzed for all patients with baseline Hb ≤10 g/dL, and by the subgroups of patients with baseline Hb ≥9 to ≤10 g/dL versus <9 g/dL. Crude and Kaplan–Meier proportions of patients who experienced each outcome and time (days) to each outcome were summarized by treatment. Meta‐analysis (fixed‐effects inverse‐variance model) was performed to compare outcomes for DA versus placebo. Safety was assessed by occurrence of adverse events. Data from 213 patients were analyzed: DA, n = 115; placebo, n = 98. More patients in the DA versus the placebo subgroup achieved Hb increase of ≥1 g/dL (72% vs. 36%; HR: 2.92, 95% CI: 1.95, 4.39) and ≥2 g/dL (44% vs. 18%; HR: 2.98, 95% CI: 1.71, 5.21) during the first 12 treatment weeks. Median times to Hb increase of ≥1 g/dL and ≥2 g/dL were 36 days and 78 days for DA, respectively. RBC or whole blood transfusions were less common in patients in the DA versus the placebo subgroup (24% vs. 45%; HR: 0.44, 95% CI: 0.27, 0.73). No new safety issues were reported. Our results confirm that DA use in patients with Stage IV cancer and CIA is more effective than placebo at increasing Hb levels and at reducing transfusion needs when DA treatment is initiated at Hb ≤10 g/dL.
‘There are two clocks in here and they are not in sync’: Counsellors' and clients' struggles with online pornography
Authors: Murray Fiona 
Published: November 2016

AbstractAt the start of the session, T stares intently at the clock on the wall before casting his gaze to the little alarm clock on the table between us. He looks at me and says, ‘there are two clocks in here and they are not in sync’. T was right about the stuttering clocks but there was something in the way he looked at me, something honest and sad, that made me think he was talking not about the clocks, but us.BackgroundThis piece offers a window into the dialogic and ethical nature of the counselling relationship in relation to online pornography. Tim has come for counselling due to his relationship breaking down over his usage of online pornography, but the counsellor's own relationship is also troubled by the same phenomenon. The affect created by this dynamic is at times intense.DiscussionThis practice exploration surfaces the therapeutic and emotional conflicts that confront a feminist female counsellor who is seeing a male client who considers himself a pornography addict and highlights the therapist's struggle to find her position between different feminist perspectives on pornography. It asks how a feminist perspective can be lived authentically within the counselling room.MethodologyThis autoethnographic work allows access through the personal and particular to the wider political and cultural life of online pornography. It asks that we stay with the uncertainty that is part of our work in the counselling room and therefore is equally as integral to our research methods.
The birth and rise of a craniopharyngioma: the radiological evolution of an incidental craniopharyngioma detected on serial MRI during medical treatment of a macroprolactinoma
Authors: Mariotti Stefano , Losa Marco , Mortini Pietro , Saba Luca 
Published: November 2016

Key Clinical MessageThis case demonstrates the rare coexistence of a prolactinoma with craniopharyngioma and documents its radiological growth. This case suggests that patients with pituitary neoplasms should be followed closely and although prolactinomas can often be managed medically, a coexistent other lesion may require surgery for histological assessment and to reduce mass effect.
ChemInform Abstract: AlFe2‐xCoB2 (x = 0—0.30): TC Tuning Through Co Substitution for a Promising Magnetocaloric Material Realized by Spark Plasma Sintering.
Authors: Hirt Sarah , Yuan Fang , Mozharivskyj Yurij , Hillebrecht Harald 
Published: November 2016

AbstractThe title compounds are prepared from the elements by arc melting, using Al flux (1673 K, 18 h), and by spark plasma sintering (893 K for 15 min and 1183 K for 20 min).
ChemInform Abstract: A New Congruent‐Melting Double Phosphate PbCd(PO3)4 with Photocatalytic Activity.
Authors: Zhou Molin , Jiang Xingxing , Xia Mingjun , Huang Hongwei , Lin Zheshuai , Yao Jiyong , Wu Yicheng 
Published: November 2016

AbstractThe title compound is prepared by calcination of stoichiometric amounts of PbO, CdO, and NH4H2PO4 with intermittent grinding (Pt crucible, 773 K, 2 d).
ChemInform Abstract: Synthesis of Metastable Co4N, Co3N, Co2N, and CoO0.74N0.24 from a Single Azide Precursor and Intermediates in CoBr2 Ammonolysis.
Authors: Widenmeyer Marc , Shlyk Larysa , Becker Nils , Dronskowski Richard , Meissner Elke , Niewa Rainer 
Published: November 2016

AbstractThe title nitrides and oxide nitride are prepared by ammonolysis of [Co(NH3)5N3]Cl2 in high purity by controlled variation of the reaction conditions (temperature, duration, gas atmosphere, and flow rate).
ChemInform Abstract: Electron‐Deficient Copper Pnictides: A2Mg3Cu9Pn7 (A: Sr, Eu; Pn: P, As) and Eu5Mg2.39Cu16.61As12.
Authors: Zhu Min , Tao Xu‐Tang , Xia Sheng‐Qing 
Published: November 2016

AbstractThe title pnictides are prepared by high temperature reactions of stoichiometric mixtures of the elements in a Pb flux (Al2O3 crucible in evacuated silica tubes, 1173 K, 24 h; cooling to 773 K at a rate of 5 K/h and subsequent Pb removal by centrifugation).
ChemInform Abstract: Photocatalytic Systems with Flavinium Salts: From Photolyase Models to Synthetic Tool for Cyclobutane Ring Opening.
Authors: Hartman Tomas , Cibulka Radek 
Published: November 2016

AbstractTwo new photocatalytic systems based on flavinium species formed in situ by protonation of riboflavin‐tetraacetate or prepared in advance via alloxazine quaternization are used as tools for the title reaction.
ChemInform Abstract: Direct Difluoromethylation of Alcohols with an Electrophilic Difluoromethylated Sulfonium Ylide.
Authors: Zhu Jiansheng , Liu Yafei , Shen Qilong 
Published: November 2016

AbstractA broad range of primary aliphatic and benzylic, secondary and even tertiary alcohols which may contain diverse functional groups is transformed according to the title reaction.
ChemInform Abstract: Sodium Amalgam Mediated Desulfonylative Reduction of α‐Functionalized β‐Ketosulfones.
Authors: Chan Chieh‐Kai , Huang Yi‐Hsuan , Chang Meng‐Yang 
Published: November 2016

AbstractThe one‐pot synthesis of secondary benzylic alcohols proceeds via radical desulfonylation of β‐ketosulfones and sequential Bouveault—Blanc reduction of the resulting ketones.
ChemInform Abstract: Rhodium‐Catalyzed Regio‐ and Stereoselective [2 + 2] Cycloaddition of Allenamides.
Authors: Zheng Wei‐Feng , Bora Pranjal Protim , Sun Gui‐Jun , Kang Qiang 
Published: November 2016

AbstractThe title reaction affords the intermolecular trans head‐to‐head cycloadducts (II) in good yields.
ChemInform Abstract: Engaging Allene‐Derived Zwitterions in an Unprecedented Mode of Asymmetric [3 + 2]‐Annulation Reaction.
Authors: Sankar Muthukumar G. , Garcia‐Castro Miguel , Golz Christopher , Strohmann Carsten , Kumar Kamal 
Published: November 2016

AbstractThe addition of a chiral spiro phosphine catalyst to an α‐substituted allene ester generates a zwitterionic dipole, which can engage isatine‐derived N‐Boc‐ketimines in a novel mode of [3 + 2] annulation.
ChemInform Abstract: Bismuth(III) Triflate‐Catalyzed Tandem Cyclizations Towards Complex Polycyclic Ethers.
Authors: Ondet Pierrick , Lempenauer Luisa , Dunach Elisabet , Lemiere Gilles 
Published: November 2016

AbstractUnder bismuth(III) triflate catalysis, α‐hydroxy enol ethers with a tethered olefinic double bond undergo a double cyclization forming bridged polycyclic compounds with an additional oxaspirocycle.
ChemInform Abstract: Copper(I)‐Catalyzed Asymmetric Dearomatization of Indole Acetamides with 3‐Indolylphenyliodonium Salts.
Authors: Liu Chuan , Yi Ji‐Cheng , Liang Xiao‐Wei , Xu Ren‐Qi , Dai Li‐Xin , You Shu‐Li 
Published: November 2016

AbstractAn intermolecular, asymmetric cascade dearomatization reaction of indole acetamides with 3‐indolylphenyliodonium salts is developed.
ChemInform Abstract: Highly Selective Intramolecular Addition of C—N and S—N Bonds to Alkynes Catalyzed by Palladium: A Practical Access to Two Distinct Functional Indoles.
Authors: Wu Chenglin , Zhao Fei , Du Yonglei , Zhao Liang , Chen Liang , Wang Jiang , Liu Hong 
Published: November 2016

AbstractTwo distinct series of functional indoles are prepared by the title addition from the same set of substrates in a catalyst‐controlled manner.
ChemInform Abstract: Construction of Chiral Tri‐ and Tetra‐Arylmethanes Bearing Quaternary Carbon Centers: Copper‐Catalyzed Enantioselective Propargylation of Indoles with Propargylic Esters.
Authors: Tsuchida Kouhei , Senda Yasushi , Nakajima Kazunari , Nishibayashi Yoshiaki 
Published: November 2016

AbstractA novel enantioselective copper‐catalyzed propargylation of N‐heterocycles is established.
ChemInform Abstract: Economical and Scalable Synthesis of 6‐Amino‐2‐cyanobenzothiazole.
Authors: Hauser Jacob R. , Beard Hester A. , Bayana Mary E. , Jolley Katherine E. , Warriner Stuart L. , Bon Robin S. 
Published: November 2016

AbstractThe reaction sequence can be performed on a multigram scale.
ChemInform Abstract: Natural Tetrahydrocurcumin in Multi‐Component Synthesis of 1,4‐Dihydropyridine Derivatives.
Authors: Ajavakom Vachiraporn , Yutthaseri Thatsawan , Ajavakom Anawat 
Published: November 2016

AbstractThe title compounds are prepared by Hantzsch reaction of tetrahydrocurcumin, benzaldehydes, and ammonium acetate in moderate yields.
ChemInform Abstract: Asymmetric Hydrogenation of Seven‐Membered C=N‐Containing Heterocycles and Rationalization of the Enantioselectivity.
Authors: Balakrishna Bugga , Bauza Antonio , Frontera Antonio , Vidal‐Ferran Anton 
Published: November 2016

AbstractThe enantioselectivity of the title reaction is rationalized by extensive DFT calculations.
ChemInform Abstract: Polymeric Complexes ‐ LXII. Coordination Chemistry of Supramolecular Schiff Base Polymer Complexes ‐ A Review
Authors: El‐Bindary A. A. , El‐Sonbati A. Z. , Diab M. A. , Ghoneim M. M. , Serag L. S. 
Published: November 2016

AbstractReview: 30 refs.
Dementia‐related adverse events in PARADIGM‐HF and other trials in heart failure with reduced ejection fraction
Authors: Cannon Jane A. , Shen Li , Jhund Pardeep S. , Kristensen Søren L. , Køber Lars , Chen Fabian , Gong Jianjian , Lefkowitz Martin P. , Rouleau Jean L. , Shi Victor C. , Swedberg Karl , Zile Michael R. , Solomon Scott D. , Packer Milton , McMurray John J.V. ,   on behalf of the PARADIGM‐HF Investigators and Committees
Published: November 2016

AimsInhibition of neprilysin, an enzyme degrading natriuretic and other vasoactive peptides, is beneficial in heart failure with reduced ejection fraction (HFrEF), as shown in PARADIGM‐HF which compared the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan with enalapril. As neprilysin is also one of many enzymes clearing amyloid‐β peptides from the brain, there is a theoretical concern about the long‐term effects of sacubitril/valsartan on cognition. Therefore, we have examined dementia‐related adverse effects (AEs) in PARADIGM‐HF and placed these findings in the context of other recently conducted HFrEF trials.Methods and resultsIn PARADIGM‐HF, patients with symptomatic HFrEF were randomized to sacubitril/valsartan 97/103 mg b.i.d. or enalapril 10 mg b.i.d. in a 1:1 ratio. We systematically searched AE reports, coded using the Medical Dictionary for Regulatory Activities (MedDRA), using Standardized MedDRA Queries (SMQs) with ‘broad’ and ‘narrow’ preferred terms related to dementia. In PARADIGM‐HF, 8399 patients aged 18–96 years were randomized and followed for a median of 2.25 years (up to 4.3 years). The narrow SMQ search identified 27 dementia‐related AEs: 15 (0.36%) on enalapril and 12 (0.29%) on sacubitril/valsartan [hazard ratio (HR) 0.73, 95% confidence interval (CI) 0.33–1.59]. The broad search identified 97 (2.30%) and 104 (2.48%) AEs (HR 1.01, 95% CI 0.75–1.37), respectively. The rates of dementia‐related AEs in both treatment groups in PARADIGM‐HF were similar to those in three other recent trials in HFrEF.ConclusionWe found no evidence that sacubitril/valsartan, compared with enalapril, increased dementia‐related AEs, although longer follow‐up may be necessary to detect such a signal and more sensitive tools are needed to detect lesser degrees of cognitive impairment. Further studies to address this question are warranted.
Average‐Cost Pricing and Dynamic Selection Incentives in the Hospital Sector
Authors: Kifmann Mathias , Siciliani Luigi 
Published: November 2016

SummaryThis study investigates dynamic incentives to select patients for hospitals that are remunerated according to a prospective payment system of the diagnosis‐related group (DRG) type. Using a model with patients differing in severity within a DRG, we show that price dynamics depend on the extent of hospital altruism and the relation between patients' severity and benefit. Upwards and downwards price movements over time are both possible. In a steady state, DRG prices are unlikely to give optimal incentives to treat patients. Depending on the level of altruism, too few or too many patients are treated. DRG pricing may also give incentives to treat low‐severity patients even though high‐severity patients should be treated. Copyright © 2016 John Wiley & Sons, Ltd.
Patients’ Perceptions of Corrective Experiences in Naturalistically Delivered Psychotherapy
Authors: Constantino Michael J. , Morrison Nicholas R. , Coyne Alice E. , Goodwin Brien J. , Santorelli Gennarina D. , Angus Lynne 
Published: November 2016

Corrective experiences (CEs), which suggest transformative experience(s) for the psychotherapy patient, have a rich theoretical history; yet there is little empirical information on patients’ own perceptions of what gets “corrected” from therapy, and what is “corrective” (i.e., the mechanisms driving the CE). To address this gap, we investigated 14 patients’ posttreatment accounts of both CE elements in the context of naturalistically delivered individual psychotherapy, using a consensual qualitative research methodology. Extending prior research focused on patients’ accounts of CEs while still engaged in treatment (Heatherington et al., 2012), the present results revealed that patients retrospectively identified an array of categories that were deemed corrected, such as positive changes in cognitions, interpersonal problems, self‐concepts, symptoms, and behaviors. Patients also identified CEs that may have led to those shifts/transformations, including their therapist's actions (especially giving feedback), their own agentic actions (especially engaging in the therapeutic process), and the patient–therapist collaborative and engaged relationship. Clinical practice implications are discussed.
RFI shielding effectiveness of a soil berm
Authors: Tezel Necmi Serkan , Reader Howard C. , Davidson David B. 
Published: November 2016

ABSTRACTWe investigate the electromagnetic (EM) shielding effectiveness (SE) properties of a berm which was created from soil due to construction works near a sensitive radio astronomy site. For the analysis, the berm is approximated as being located above an infinite perfectly electric conducting (PEC) plane. A two‐dimensional cross‐sectional analysis is shown to be sufficient to investigate the SE, which we compute using a computationally efficient single‐layer boundary integral equation method. To verify the method, we compare our results against those obtained by the commercially available Method of Moments (MoM) code, FEKO. Good agreement is demonstrated. It is observed that the berm provides about 25–30 dB SE at heights lower than 5 m and at distances of up to 50 m from the berm. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:17–21, 2017
High‐gain mixer using cascode current bleeding and gm‐boosting techniques
Authors: Lee Ji‐Young , Yun Tae‐Yeoul 
Published: November 2016

ABSTRACTThis paper presents a high‐gain down‐conversion mixer using a cascode current bleeding technique and a transconductance (gm)‐boosting technique. Unlike the conventional folded‐type mixer, an nMOS input transconductance transistor is allocated under pMOS switching transistors and load resistors in the proposed mixer. This topology allows the folded mixer to reuse the total current at the input transconductance transistor for low power consumption and to adopt the current bleeding technique for high gain. In addition, the gm‐boosting technique increases effective transconductance by adding a positive‐feedback inductor. Measured results show a maximum voltage conversion gain of 23.8 dB, an input third‐order intercept point (IIP3) of −10.5 dBm at the maximum gain, a minimum noise figure of 4.3 dB, and a 3‐dB bandwidth from 7.2 to 8.4 GHz with a consumption of 3.9 mW from a 1.2 V supply. The chip size, including test pads, is 0.9 × 0.95 mm2 using 0.13 μm RF CMOS technology. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:1–6, 2017