bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Mediating Role of Psychological Contract Breach in the Influence of Leader-Member Exchange on Quiet Quitting Among Coaches
Authors: BARAN Hilal , KARAVELİOĞLU Ceren , KARAVELİOĞLU Mihri Barış 
Published: October 2024

Abstract

Background: The research is intended to clarify the relationship among leader-member exchange (LMX) quiet quitting and psychological contract breach variables grounded in social exchange theory which explains the motivations individuals exhibit in reciprocal relationships. Additionally it seeks to elucidate the mediating function of psychological contract breach in the association between LMX and quiet quitting.
Methods: The research model was evaluated using regression and mediation analyses on data obtained from 294 coaches.
Results: The research findings indicate that LMX diminishes the perception of psychological contract breach. This finding indicates that coaches with robust LMX will experience diminished perceptions of psychological contract breach subsequently reducing their quiet quitting behaviors.
Ethics approval number: 244222 date of registration: 17/11/2023
Conclusion: LMX adversely impacts psychological contract breach and quiet quitting whereas psychological contract breach positively influences quiet quitting. Furthermore the perception of psychological contract breach mediates the relationship between LMX and quiet quitting.
IL2RG’s Expression and its associated Long Non-Coding RNAs signature in ccRCC: Development, Validation, and Im-plications for Diagnosis,Prognosis,and Treatment
Authors: Hu Weijing , Chen Yongquan , Guo Xiaoling , Wang Xiaosong , Wang Dongwen , Wu Bo 
Published: October 2024

Abstract

Background: Interleukin-2 Receptor Subunit Gamma (IL2RG) has been implicated in various cancers, but its role in clear cell renal cell carcinoma (ccRCC) remains unclear. This study aimed to explore IL2RG expression, its relationship with IL2RG -related lncRNAs (IRLs).
Methods: qRT-PCR and IHC were used to assess IL2RG expression in ccRCC tissues and cell lines. Pearson correlation analysis identified IRLs related to IL2RG, and LASSO regression was applied to develop a prognostic model. We also conducted drug sensitivity analysis.
Results: IL2RG was significantly upregulated in ccRCC tissues and correlated with advanced clinical stages (p<0.001). High IL2RG expression was linked to worse overall survival (OS), disease-specific survival (DSS), and progression-free interval (PFI) (p<0.05). A 6-IRLs signature was identified, and the resulting model accurately predicted survival outcomes. Immune-related pathways were enriched in high-risk patients, and drug sensitivity analysis indicated that high-risk patients were more responsive to sunitinib and temsirolimus.
Conclusions: IL2RG and its related 6-IRLs are potential biomarkers for ccRCC progression. The 6-IRLs model provides a robust tool for predicting prognosis and guiding therapeutic decisions.
The value of inflammation-related indicators in chemotherapy efficacy and DFS of triple-negative breast cancer
Authors: Zhu Jie , Cheng Jiale , Ma Yuyuan , Wang Ying , Zou Zhonghua , Wang Wenjie , Shi Haihua , Meng You 
Published: October 2024

Abstract

Background: Neoadjuvant chemotherapy (NAC) is an important measure for improving the prognosis of early operable Triple-negative breast cancer (TNBC) patients. Inflammation-related indicators can predict the outcome of TNBC patients.
Methods: Kaplan-Meier curves were used to evaluate survival. The correlation between these indicators and NAC efficacy was analyzed using t-tests. Models for univariate and multivariate Cox regression analyses were performed to determine the independent risk factors. A nomogram was used for the prediction of one-, two-, and three-year disease-free survival (DFS).
Results: IL-6, PLR, SII, and Ki-67 levels were associated with neoadjuvant efficacy. IL-6, PLR, SII, Ki-67, and lymphocyte count were associated with DFS. The risk score for each TNBC patient was obtained using LASSO regression analysis to construct a prognostic model. In the prognostic model, patients in the high-risk score group showed worse DFS than those in the low-risk group. Risk score and tumor size were independently correlated with outcomes in multivariate Cox regression analysis. A nomogram was constructed using IL-6, PLR, SII, Ki67, and Miller-Payne (MP) scores. Calibration curves demonstrated good consistency between the actual and predictive values of the nomogram.
Conclusion: A prognostic model was established by combining four prognosis-related indicators in TNBC patients who underwent NAC.
Assessment and Quantitative Analysis of Hip Surrounding Muscles in Children with Developmental Dysplasia of the Hip via Magnetic Resonance Imaging
Authors: Duan Lian , Zhou Weizheng , Li Lianyong 
Published: October 2024

Abstract

Background
The muscles that encase the hip serve a crucial role in both joint stability and functional efficacy, and as developmental dysplasia of the hip (DDH) progresses, the surrounding musculature may undergo specific adaptations that reduce joint stability, thereby exacerbating dislocation. Yet, the exact nature of changes in muscle morphology and quality remains inadequately investigated. This study aims to compare magnetic resonance imaging (MRI) evaluations of the iliopsoas and other hip flexor and extensor muscles in children with unilateral DDH before and after treatment.
Methods
Children with unilateral DDH were included in this study and compared to a matched control group. Using T2-weighted MRI sequences, muscle cross-sectional area (CSA) and fat infiltration (FI) were measured for the iliopsoas, sartorius, rectus femoris, tensor fasciae latae, and gluteus maximus. The cross-sectional area ratio (CSAr) was calculated as the CSA of the affected side divided by the CSA of the healthy side, corresponding to the respective sides in normal controls. For long-term follow-up (≥ 5 years), data from DDH children were analyzed, categorized into groups based on treatment. Comparisons of muscle CSAr and FI at the final follow-up were made against preoperative levels.
Results
Preoperative median CSAr values for the iliopsoas, rectus femoris, and gluteus maximus in DDH children were significantly lower than those of the control group (P < 0.001). FI levels were also higher in the DDH group compared to controls. In the closed reduction group, iliopsoas CSAr increased and FI decreased at the final follow-up compared to preoperative measurements. Conversely, in the open reduction group, iliopsoas CSAr and FI decreased. In the Dega osteotomy group, both iliopsoas CSAr and FI decreased, while CSAr for the sartorius, rectus femoris, and gluteus maximus increased, with also reduced FI.
Conclusion
Children with DDH exhibit varying degrees of muscle atrophy and increased fat infiltration compared to their age-matched healthy counterparts. Aside from the iliopsoas, muscle morphology and fat infiltration in DDH children improved post-treatment compared to pre-treatment levels.
Identification of pyroptosis-related biomarkers in venous thromboembolism
Authors: Han Shengbin , Xu Jingzhe , Wang Lianlin , Wang Jiarong , Yu Chenchen , Guan Hongxi , Ding Shun 
Published: October 2024

Abstract

OBJECTIVE
The study was designed with the aim of excavating diagnostic biomarkers of venous thromboembolism (VTE).
METHODS
The GSE19151 and GSE48000 datasets were subjected into this study. The pyroptosis-related genes (PRGs) were sourced from literature1. Differential expression analysis and WGCNA were applied to identify differential genes related with Pyroptosis (DE-PRGs) in VTE. The possible functions of DE-PRGs were defined by means of enrichment analysis. The biomarkers related with pyroptosis in VTE were determined by plotting receiver operating characteristic (ROC) curve. The gene set enrichment analysis (GSEA) was employed to analyze the correlation between biomarkers and pathways. Finally, the quantificational Reverse Transcription-Polymerase Chain Reaction (qRT-PCR) was proceeded to verify the expression level of the biomarkers in VTE.
RESULTS
A number of 52 DE-PRGs were identified by feat of differential expression analysis and WGCNA. A number of five biomarkers (RPL31, RPL34, RPL9, RPS27L and HINT1) were further screened by ROC curves. GSEA pointed to the linkage of five biomarkers to the ribosome proteins and oxidative phosphorylation signaling transduction, which may cause cell pyrodeath and trigger VTE through mitochondrial pathways. qRT-PCR manifested the expression levels of RPL31, RPL9 and HINT1 were all observably higher in VTE samples than in normal samples.
CONCLUSION
A number of five biomarkers, RPL31, RPL34, RPL9, RPS27L and HINT1, were identified as pyroptosis-related biomarkers in VTE, which provided a basis for understanding VTE pathogenesis and new insights into VTE diagnosis and treatment.
WITHDRAWN: The impact of listing companies in emerging markets on the London Stock Exchange on Financial reporting opacity and sustainable growth rate
Authors: Elmaasrawy Hamada , Tawfik Omar , Lamey Ywana 
Published: October 2024

Abstract

Purpose: This paper aims to examine the impact of listing firms listed in emerging markets on the London Stock Exchange (LSE) on both financial reporting opacity (FRO) and the sustainable growth rate, as well as the impact of FRO on the sustainable growth rate (SGR).
Design/methodology/approach; Sample of 77 Egyptian Firms was relied on during the period from 2014 to 2023 with a total of 693 observations. The study uses OLS and 2SLS to test research hypotheses.
Findings: The study found that there is a positive relationship between the listing of Firms in emerging markets on LSE and FRO, while there is no relationship between the listing of Firms in emerging markets on LSE and the rate of SGR, while there is a negative relationship between FRO and SGR.
Research limitations; This research is limited to Firms listed on LSE and therefore the rest of the other European stock exchanges are excluded, this research is also limited to Egyptian Firms listed first in the Egyptian Stock Exchange and then listed on LSE and not Firms listed on LSE and then listed on the Egyptian Stock Exchange, as well as the research is limited to analyzing the financial reports of the issuing Firms in the local language
Practical implications: The results of this study are useful to the regulatory and supervisory authorities in developing countries, taking into account the objectives of Firms from listing in emerging markets and that there is a minimum limit for listing in global markets. In addition, current and potential investors should realize that simply listing the company on a foreign stock exchange does not necessarily mean the quality of financial reporting and sustainable growth rates, as well as financial institutions should not rely on the reputation gained by Firms listed on international stock exchanges, but must It do a good audit of the financial reports of Firms listed on international stock exchanges.
Originality/Value; This study is the first of its kind within the limits of researchers' knowledge, which deals with the impact of listing developing country Firms (Egyptian Firms as an example) on SGR, this study is the first of its kind (within the limits of researchers' knowledge), which focuses on listing emerging market Firms (Egyptian Firms as an example) on LSE without other stock exchanges and its impact on FRO and the SGR.
Pisa syndrome induced by discontinuation of low dose sulpiride: a case report
Authors: Koyama Genki , Nakano Masaki , Takata Taketo , Mimura Yu , Uchida Hiroyuki , Funayama Michitaka 
Published: October 2024

Abstract

Background
Pisa syndrome is a type of dystonia characterized by lateral flexion of the trunk, often induced by cholinesterase inhibitors and antipsychotics. Seemingly opposite hypotheses of the underlying mechanism have been proposed: cholinergic-dopaminergic imbalance toward cholinergic dominance and dopamine hypersensitivity associated with long-term antipsychotic administration.
Case presentation:
We herein report a case of a 64-year-old woman presenting with Pisa syndrome immediately after discontinuation of low dose sulpiride. To the best of our knowledge, this is the first case of Pisa syndrome induced by withdrawal of sulpiride, an antipsychotic that preferentially binds to presynaptic dopaminergic receptors at low doses, presumably resulting in increased dopaminergic action.
Conclusions
Our case not only supports the cholinergic-dopaminergic imbalance hypothesis as the mechanism underlying Pisa syndrome, but also suggests the paradoxical dopaminergic effects of sulpiride.
Population Genetic Structure Analysis of Anopheles kleini in the Republic of Korea based on the Mitochondrial COI Gene
Authors: Jung Haneul , Han Bo Gyeong , Ju Jung-Won , Lee Hee-Il , Shin Hyun-Il 
Published: October 2024

Abstract

Background
Anopheles kleini is a competent vector mainly observed in the northern malaria-risk areas of the Republic of Korea (ROK). In this study, the population genetic structure of An. kleini was analyzed for the first time in the ROK using the mitochondrial cytochrome c oxidase subunit Ⅰ (COI) marker.
Methods
The genetic structure of 249 An. kleini from three statistically analyzable regions was analyzed.
Results
Network analysis identified 140 haplotypes organized into three clusters. Cluster Ⅱ was related to An. kleini from eastern Russia and northwestern China. The pairwise genetic distance (FST) values among the populations showed regional genetic differences between Gangwon-do and Gyeonggi-do. Analysis of molecular variance (AMOVA) indicated that individual mosquitoes within the population had a significant influence on the total variation. The neutrality test, using three methods (Fu’s Fs, Fu, and Li’s D, and Fu and Li’s F), indicated that all values were negative, suggesting that An. kleini is an expanding population. An. kleini in Yanggu has a significant difference in genetic distance from other regions.
Conclusion
Based on molecular epidemiology, the spatial population structure of An. kleini is crucial in understanding the characteristics of An. kleini populations.
Diagnosis of Langerhans cell histiocytosis via percutaneous liver biopsy
Authors: Chen Qian-Qian , Zhao Chang , Shao Chun-kui , Zhang Yi-wang , Chen Jian-ning , Li Hai-feng , Liang Qiong 
Published: October 2024

Abstract

Background: The aims were to assess the clinical and histopathological characteristics of Langerhans cell histiocytosis (LCH) based on percutaneous liver biopsy and to improve the technique’s diagnostic accuracy.
Methods: Data from seven patients were collected. The clinicopathological features and immunophenotypes of hepatic LCH in the biopsied tissues were evaluated .
Results: Five men and two women (median age: 21 years) were included. The clinical presentations and imaging findings were unremarkable. In terms of the histological findings, multifocal and solitary lesions were detected in six patients and one patient, respectively. All lesions were located in the portal area and exhibited either enlarged or normal portal tracts. In four patients, Langerhans cells (LCs) were distributed either in clusters or scattered among mixed populations of inflammatory cells.LC invasion of the bile duct epithelium was detected in all but one patient; that individual presented with sclerosing cholangitis (SC) in the absence of LCs. One patient had a similar inflammatory myofibroblastic tumor (IMT) or inflammatory pseudotumor-like follicular dendritic cell (FDC) tumor. One patient had suppurative cholangitis with abscess formation, accompanied by a small degree of LC invasion into the bile duct epithelium.
Conclusions: The morphology of liver LCHs varied among patients. Bile duct epithelial damage accompanied by eosinophilic infiltration, a history of extrahepatic LCH, or central diabetes insipidus are clues that LCH may be present; however, H&E staining and IHC are crucial for its diagnosis. LCH should be differentiated from hepatic parasitic infections, primary SC, inflammatory pseudotumor-like FDC tumors, and inflammatory myofibroblastoma.
Falcon anti-quantum attack scheme based on 8-qubits channel RSP
Authors: Peng Kexin , Du Siyu 
Published: October 2024

Abstract

Quantum secure communication is divided into two key branches: quantum teleportation and quantum state remote preparation. The objective of quantum state remote preparation is to leverage classical communication and quantum entanglement for creating known quantum states at remote locations. Given that these known quantum states encompass amplitude coefficients, transmitting them over classical channels poses a security risk. This proposed solution emulates a scenario of three-party controlled remote preparation involving sender Alice, receivers Bob and Charlie, and controller Eve sharing an 8-bit quantum transmission channel. The plan entails preparing a dual quantum transmission channel at Bob and a triple quantum transmission channel at Charlie, followed by employing linear independent measurements and single quantum measurements, respectively. This approach effectively facilitates a positive operation at the receiving end to restore the original quantum state, ensuring secure quantum transmission. Furthermore, the solution integrates the Falcon post-quantum encryption algorithm for identity authentication on the amplitude coefficients, thereby thwarting potential information theft and tampering by malicious third parties. Through security analysis, efficiency comparisons, and validation via quantum simulators and Falcon code experiments, this solution notably enhances the efficiency of quantum state remote preparation while upholding performance integrity on classical channels. By enabling secure transmission on the channel, it enhances resilience against intermediary attacks.
Rapid Verbal Persuasion to Increase Influenza Vaccine Uptake: Protocol for a Randomized Hybrid Type 2 Effectiveness -Implementation Trial
Authors: Liu Siyuan , Gao Lan , Jin Yingying , Chen Jiangyun , Wu Dadong , Cai Yiyuan , Wang Tao , Huang Sanhao , Yan Ciling , Wang Run , Xu Dong (Roman) 
Published: October 2024

Abstract

Background
While influenza vaccines are the most effective measure for preventing influenza, uptake rates in China remain relatively low. Rapid Verbal Persuasion (RVP), due to its highly rapid fashion, involving just 1–2 minutes, has a strong evidence base in promoting behavior change. Despite this, it is underused or rarely evaluated in the context of vaccination. Additionally, the success of RVP implementation in vaccination clinics hinges on the motivation of the vaccination staff, which remains critical even with stable contextual factors. Multifaceted incentive-based implementation strategies, which aim to enhance motivation to promote the implementation of evidence-based practices, could be advantageous. This study protocol outlines an implementation-effectiveness hybrid type 2 design to evaluate the effectiveness of both the incentive-based implementation strategies on implementation outcomes and RVP on increasing influenza vaccination rates.
Method
This study will be conducted as a two-tiered cluster of randomized controlled trials over three months. Initially, 32 vaccination clinics will be randomly allocated to one of two study arms: (a) implementation of RVP or (b) no implementation. At the end of the study period, differences in influenza vaccination status between the intervention and control groups will be compared (primary outcome). Subsequently, a cluster randomized factorial trial will be conducted, involving 16 clinics implementing RVP. This trial will aim to compare the impact of various implementation strategies (different combinations of incentives) on fidelity in RVP implementation (Primary outcome). Data collection for the primary outcomes will include unannounced exit interviews. Modified Poisson regression models and generalized linear mixed-effects models will be utilized to analyze the association between primary outcomes and interventions.
Conclusion
The study aims to enhance the influenza vaccination rate in China by developing financial and non-financial incentives that allow vaccination staff to deliver RVP with greater motivation. Furthermore, the evidence generated from this multi-center trial will assist policymakers in improving current incentive systems within immunization services.
Number Line Estimation: another view in the light of the ACE, Arithmécole, and ELFE data.
Authors: Fischer Jean-Paul 
Published: October 2024

Abstract

Background. Numerous experimental or empirical papers using a number line estimation task have already been published. In this task, the participant must indicate the position of a number (e.g., 12) on a line bounded by two numbers (e.g., 0 and 100). However, the authors of these articles mainly sought to model the representation of numbers based on data obtained from participants.
Methods. This research draws on data from three French studies, each involving several thousand primary students, with an educational perspective. These data made it possible to investigate questions that have rarely been addressed, such as the singularity of this task and the asymmetry of the influence of the bounds. More importantly, they have enabled a systematic analysis of students' errors with the task presented in the form of multiple choice.
Results. Qualitative principal component and automated classification analyzes show some singularity of the number line task (in its multiple-choice exercise, at least). The asymmetry of the influence of the two bounds argues against the two main models in the literature—the logarithmic model and the linear model. The analysis of the approximately 100,000 students' erroneous choices reveals that they do not completely respect their distance to the correct choice: The expected order of choice through genuine estimation, that is first the correct number, then the nearest wrong number, then the middle wrong number and lastly the farthest wrong number, was not respected in more than half of the 46 number line estimation items. Furthermore, young children exhibited under-comprehension by confounding the magnitude of the target number with its position value, and educators or school authorities do not clearly understand the task or its modeling.
Conclusions. No model predicts all the observations, often original or curious, that we have made. Moreover, for theoretical reasons, we believe that the search for such a model is somewhat vain. In addition, we are sceptic about using the task for anything other than student assessment, given the distortions and difficulties that emerge from the children's erroneous choices, and from the practices of teachers and their supervisors also discussed in the article.