bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reciprocal relations between intrinsic reading motivation and reading competence: A comparison between native and immigrant students in Germany
Authors: Miyamoto Ai , Pfost Maximilian , Artelt Cordula 
Published: May 2017

The present study compares native and immigrant students regarding the direction and the strength of the relation between intrinsic reading motivation and reading competence. Within the framework of the German National Educational Panel Study, 4,619 secondary school students were included in the analyses. The present study confirmed the reciprocal cross‐lagged effects between intrinsic reading motivation and reading competence from grades 5 to 7 for native students. In addition, the effect of grade 5 intrinsic reading motivation on grade 7 reading competence was mediated by grade 6 reading amount. However, for immigrant students, although the cross‐lagged effect of grade 5 reading competence on grade 7 intrinsic reading motivation was significant, the reverse effect was not significant. The present findings suggest that intrinsic reading motivation seems to be essential for the development of reading achievement for native students whereas it seems to be of less importance for immigrant students.HighlightsWhat is already known about this topic?

Intrinsic reading motivation and reading competence are significantly and positively correlated with each other.
The relation between intrinsic reading motivation and reading competence is mediated by reading amount.
In comparison to native students, immigrant students show lower reading competence despite comparable or even higher levels of reading motivation.
What this paper adds

Empirical evidence on the reciprocal effects between intrinsic reading motivation and reading competence.
Empirical support for the significant indirect effect of intrinsic reading motivation on reading competence through reading amount using longitudinal data.
Students' immigration status moderates the direction and the strength of the relation between intrinsic reading motivation and reading competence.
Implications for theory, policy, or practice

Increase in reading competence seems to lead to higher levels of intrinsic reading motivation regardless of students' immigration background.
Promoting students' intrinsic reading motivation seems to lead to better reading competence for native students but not for immigrant students.
Especially with regard to immigrant students, educators should take the availability of adequate reading opportunities into account.
Autopsy Fingerprint Technique Using Fingerprint Powder
Authors: Morgan Lee O. , Johnson Marty , Cornelison Jered B. , Isaac Carolyn V. , deJong Joyce L. , Prahlow Joseph A. 
Published: May 2017

AbstractThe collection of high‐quality fingerprints is an important component of routine forensic autopsies and represents one of the several potential methods for identifying a decedent. Fingerprint collection at autopsy frequently employs a manual method using fingerprint ink and cards, although some offices use digital‐scanning equipment. While these methodologies are adequate in most circumstances, this study introduces an alternative method using fingerprint powder and adhesive labels. The method is quick, easy to perform, and cost‐effective and provides the additional advantage of an adhesive label that easily conforms to the finger, palm, or foot which reduces smudging of prints in individuals with rigor mortis, skin slippage, or decomposition compared to more traditional autopsy fingerprint collection techniques. The prints can then be easily stored, either in hard‐copy form or scanned to make a digital record.
Genetic assignment with isotopes and habitat suitability (gaiah), a migratory bird case study
Authors: Ruegg Kristen C. , Anderson Eric C. , Harrigan Ryan J. , Paxton Kristina L. , Kelly Jeffrey F. , Moore Frank , Smith Thomas B. 
Published: May 2017

Summary

Identifying migratory connections across the annual cycle is important for studies of migrant ecology, evolution and conservation. While recent studies have demonstrated the utility of high‐resolution SNP‐based genetic markers for identifying population‐specific migratory patterns, the accuracy of this approach relative to other intrinsic tagging techniques has not yet been assessed.

Here, using a straightforward application of Bayes’ Rule, we develop a method for combining inferences from high‐resolution genetic markers, stable isotopes and habitat suitability models, to spatially infer the breeding origin of migrants captured anywhere along their migratory pathway. Using leave‐one‐out cross validation, we compare the accuracy of this combined approach with the accuracy attained using each source of data independently.

Our results indicate that when each method is considered in isolation, the accuracy of genetic assignments far exceeded that of assignments based on stable isotopes or habitat suitability models. However, our joint assignment method consistently resulted in small, but informative increases in accuracy and did help to correct misassignments based on genetic data alone. We demonstrate the utility of the combined method by identifying previously undetectable patterns in the timing of migration in a North American migratory songbird, the Wilson's warbler.

Overall, our results support the idea that while genetic data provides the most accurate method for tracking animals using intrinsic markers when each method is considered independently, there is value in combining all three methods. The resulting methods are provided as part of a new computationally efficient R‐package, gaiah, allowing broad application of our statistical framework to other migratory animal systems.
Early experience with totally laparoscopic major hepatectomies: single institution experience with 31 consecutive cases
Authors: Goh Brian K. P. , Chan Chung Yip , Lee Ser Yee , Chung Alexander Y. F. 
Published: May 2017

BackgroundTotally laparoscopic major hepatectomy (LMH) is a technically challenging procedure with limited studies mainly from high‐volume expert centers reported. In this study, we report our initial experience with totally LMH.MethodsA retrospective review of a prospective database of 340 consecutive patients who underwent laparoscopic liver resection at a single institution was conducted. Thirty‐one consecutive patients who underwent attempted totally LMH between March 2011 to December 2016 were identified. Major hepatectomies were defined as resection of ≥3 contiguous segments which included only right/left hepatectomies, extended hepatectomies or central hepatectomies.ResultsThe procedures included 11 right hepatectomies, one extended right hepatectomy, nine left hepatectomies (two including middle hepatic vein), two extended left hepatectomies, two left hepatectomies with caudate lobe and six central hepatectomies. The median tumor size was 40 (range, 12–100) mm and the median operation time was 435 (range, 245–585) min. Median blood loss was 500 (range, 100–1900) mls and 10 (32.3%) patients required blood transfusion. There were three (9.7%) open conversions of which two occurred during the first five cases. There was one (3.2%) major (>grade 2) morbidity and there were no 30‐day/in‐hospital mortalities or reoperations. The median postoperative stay was 5 (range, 3–14) days.ConclusionOur initial experience confirms the feasibility and safety of LMH. There was an increase in the number and proportion of LMH performed at our institution over time.
The use of Imatinib resistance mutation analysis to direct therapy in Philadelphia chromosome/BCR‐ABL1 positive chronic myeloid leukaemia patients failing Imatinib treatment, in Patan Hospital, Nepal
Authors: Kayastha Gyan K. , Ranjitkar Nora , Gurung Radha , KC Raj Kumar , Karki Sanjit , Shrestha Roshan , Rajbhandari Piyush , Thapa Raj K. , Poudyal Buddhi , Acharya Paras , Roberts David J. , Hayes Bruce , Zimmerman Mark , Basnyat Buddha 
Published: May 2017

SummaryPhiladelphia chromosome/BCR‐ABL1 positive chronic myeloid leukaemia (CML) can be successfully treated with Glivec (Imatinib), which is available free of cost through the Glivec International Patient Assistance programme (GIPAP) to patients with proven CML without means to pay for the drug. We review the acquired mutations in the tyrosine kinase encoded by the BCR‐ABL1 gene underlying Glivec failure or resistance in a cohort of 388 imatinib‐treated CML patients (149 Female and 239 male) registered between February 2003 and June 2016 in Nepal. Forty‐five patients (11 female 34 male) were studied; 18 different BCR‐ABL1 mutations were seen in 33 patients. P‐loop mutation, Kinase domain and A‐loop mutations were seen in 9, 16 and 4 patients respectively. Other mutations were seen in five patients. A T315I mutation was the most common mutation, followed by F359V and M244V. Sixteen mutations showed intermediate activity to complete resistance to Glivec. Among the 45 patients evaluated for BCR‐ABL1 mutations, 4 were lost to follow‐up, 14 died and 27 are still alive. Among the surviving patients, 16 are receiving Nilotinib, 5 Dasatinib and 3 Ponatinib, while 3 patients were referred to India, one of who received allogenic bone marrow transplantation. Understanding the spectrum of further acquired mutations in BCR‐ABL1 may help to choose more specific targeted tyrosine kinase inhibitors that can be provided by GIPAP.
Training future haematologists, a privilege or a burden? “A trainer's view”
Authors: Shlebak Abdul A. , Bain Barbara J. 
Published: May 2017

SummaryRecent decades have seen the emergence of new problems in haematology training, relating particularly to an expanding curriculum, less time available for training, staff shortages and the increasing separation of clinical haematology from its laboratory base. We have sought to identify the problems and propose possible solutions.
A retrospective analysis of 3954 patients in phase 2/3 trials of bortezomib for the treatment of multiple myeloma: towards providing a benchmark for the cardiac safety profile of proteasome inhibition in multiple myeloma
Authors: Laubach Jacob P. , Moslehi Javid J. , Francis Sanjeev A. , San Miguel Jesús F. , Sonneveld Pieter , Orlowski Robert Z. , Moreau Philippe , Rosiñol Laura , Faber Edward A. , Voorhees Peter , Mateos Maria‐Victoria , Marquez Loreta , Feng Huaibao , Desai Avinash , van de Velde Helgi , Elliott Jennifer , Shi Hongliang , Dow Edward , Jobanputra Nishith , Esseltine Dixie‐Lee , Niculescu Liviu , Anderson Kenneth C. , Lonial Sagar , Richardson Paul G. 
Published: May 2017

SummaryThis retrospective analysis aimed to establish the overall cardiac safety profile of bortezomib using patient‐level data from one phase 2 and seven phase 3 studies in previously untreated and relapsed/refractory multiple myeloma (MM). Seven clinically relevant primary [congestive heart failure (CHF), arrhythmias, ischaemic heart disease (IHD), cardiac death] and secondary (hypertension, dyspnoea, oedema) cardiac endpoints were defined based on MedDRA v16.0 preferred terms. 2509 bortezomib‐treated patients and 1445 patients in non‐bortezomib‐based control arms were included. The incidence of grade ≥3 CHF was 1·3–4·0% in studies in relapsed/refractory MM and 1·2–4·7% in previously untreated MM (2·0–7·6% all grades), with no significant differences between bortezomib‐ and non‐bortezomib‐based arms in comparative studies. Incidences of arrhythmias (1·3–5·9% grade ≥2; 0·6–4·1% grade ≥3), IHD (1·2–2·9% all grades; 0·4–2·7% grade ≥3) and cardiac death (0–1·4%) were low, with no differences between bortezomib‐based and non‐bortezomib‐based arms. Higher rates of oedema (mostly grade 1/2) were seen in bortezomib‐based versus non‐bortezomib‐based arms in one study and a pooled transplant study analysis. Logistic regression analyses of comparative studies showed no impact on cardiac risk with bortezomib‐based versus non‐bortezomib‐based treatment. Bortezomib‐based treatment was associated with low incidences of cardiac events.
Loss of Dynamin 2 GTPase function results in microcytic anaemia
Authors: Brown Fiona C. , Collett Michael , Tremblay Cedric S. , Rank Gerhard , De Camilli Pietro , Booth Carmen J. , Bitoun Marc , Robinson Phillip J. , Kile Benjamin T. , Jane Stephen M. , Curtis David J. 
Published: May 2017

SummaryIn a dominant mouse ethylnitrosurea mutagenesis screen for genes regulating erythropoiesis, we identified a pedigree with a novel microcytic hypochromia caused by a V235G missense mutation in Dynamin 2 (Dnm2). Mutations in Dnm2, a GTPase, are highly disease‐specific and have been implicated in four forms of human diseases: centronuclear myopathy, Charcot‐Marie Tooth neuropathy and, more recently, T‐cell leukaemia and Hereditary Spastic Paraplegia, but red cell abnormalities have not been reported to date. The V235G mutation lies within a crucial GTP nucleotide‐binding pocket of Dnm2, and resulted in defective GTPase activity and incompatibility with life in the homozygous state. Dnm2 is an essential mediator of clathrin‐mediated endocytosis, which is required for the uptake of transferrin (Tf) into red cells for incorporation of haem. Accordingly, we observed significantly reduced Tf uptake by Dnm2+/V235G cells, which led to impaired endosome formation. Despite these deficiencies, surprisingly all iron studies were unchanged, suggesting an unexplained alternative mechanism underlies microcytic anaemia in Dnm2+/V235G mice. This study provides the first in vivo evidence for the requirements of Dnm2 in normal erythropoiesis.
Concurrent and Subsequent Associations Between Daily Digital Technology Use and High‐Risk Adolescents’ Mental Health Symptoms
Authors: George Madeleine J. , Russell Michael A. , Piontak Joy R. , Odgers Candice L. 
Published: May 2017

Adolescents are spending an unprecedented amount of time using digital technologies (especially mobile technologies), and there are concerns that adolescents’ constant connectivity is associated with poor mental health, particularly among at‐risk adolescents. Participants included 151 adolescents at risk for mental health problems (Mage = 13.1) who completed a baseline assessment, 30‐day ecological momentary assessment, and 18 month follow‐up assessment. Results from multilevel regression models showed that daily reports of both time spent using digital technologies and the number of text messages sent were associated with increased same‐day attention deficit hyperactivity disorder (ADHD) and conduct disorder (CD) symptoms. Adolescents’ reported digital technology usage and text messaging across the ecological momentary assessment (EMA) period was also associated with poorer self‐regulation and increases in conduct problem symptoms between the baseline and follow‐up assessments.
Younger age is a risk factor for regrowth and recurrence of nonfunctioning pituitary macroadenomas: Results from a single Australian centre
Authors: Watts Anna K. , Easwaran Abhishek , McNeill Peter , Wang Yi Yuen , Inder Warrick J. , Caputo Carmela 
Published: May 2017

SummaryObjectiveThe natural history of nonfunctioning pituitary macroadenomas (NFPMA) after surgical resection is variable, with guidelines unable to define the duration of radiological follow‐up. In this first Australian series, we identify risk factors for regrowth/recurrence of NFPMA to assist with guiding recommendations for long‐term follow‐up.DesignRetrospective analysis of all radiotherapy‐naïve cases with NFPMA resected between 1995 and 2013.PatientsOne hundred and twenty‐three cases had both ≥2 postoperative scans and ≥12‐month follow‐up.MeasurementsRegrowth was defined as any sustained increase in diameter of residual adenoma or recurrence as any new adenoma occurring post complete resection on serial pituitary MRI.ResultsMedian follow‐up time was 48 months (interquartile range [IQR]: 31‐86). Overall regrowth/recurrence occurred in 29% (36/123). Regrowth occurred in 40% (30/76) at a median time of 44.5 months (IQR 22‐80) compared to recurrence of 12.5% (6/48; P=.003), occurring at a median time of 48 months (IQR 12‐96; P=.7). Further treatment was required in 66.7% and 56.7%, respectively (=1.0). Risk factors for regrowth/recurrence by multivariate analysis were presence of residual disease and younger age at presentation. The longest time for regrowth was 168 months (14 years) and recurrence 156 months (13 years).ConclusionsPresence of postoperative residual adenoma and younger age at presentation are the main predictors of regrowth/recurrence in NFPMA. Long‐term serial imaging is required to detect regrowth and recurrence in younger patients and those with residual disease. Most regrowth/recurrences will occur within 10 years of follow‐up.
Reference value of induced sputum cell counts and its relationship with age in healthy adults in Guangzhou, Southern China
Authors: Luo Wei , Chen Qiaoli , Chen Ruchong , Xie Yanqing , Wang Hui , Lai Kefang 
Published: May 2017

AbstractPurposeTo establish the reference value of total and differential cell counts in induced sputum in healthy adults in Guangzhou, and to explore the relationship of age and gender with sputum cell counts.MethodsA total of 185 healthy, nonatopic, never‐smokers between 19 and 74 years old underwent induced sputum test with hypertonic saline (3%) inhalation. Sputum samples were collected for total and differential cell counts.ResultsQualified sputum samples were obtained from 153 subjects (mean age: 43 ± 17) with a success rate of 82.7% (153/185). The mean Standard Deviation (STDEV) and 2.5% to 97.5% percentile total cell counts were 2.1 × 106/g (1.0), (.7–4.5 × 106/g). The mean STDEV and 2.5% to 97.5% percentile differential cell counts were as follows: neutrophil 38.3% (17.7), (8.9%–72.9%); macrophage 58.9% (17.7), (24.7%–90.0%); eosinophils: median, .3%; interquartile range (IQR), 1.1%; and .0% to 95.0% percentile, .0% to 2.0%; and lymphocytes: median, 1.0%; IQR, 1.8%; and .0% to 95.0% percentile, .0% to 4.5%. There was positive correlation of age with the percentage of neutrophil and eosinophil (r = .659, r = .402; P < .001). The percentage of neutrophil, macrophage and eosinophil were significantly different among different age groups. The total cell counts and sputum cell counts were comparable between males and females.ConclusionsThis study initially establishes reference value of induced sputum cell counts in healthy adults in Guangzhou, Southern China, and it verifies that neutrophilic and eosinophilic counts increase by age.
Management of patients with malignancies and secondary immunodeficiencies treated with immunoglobulins in clinical practice: Long‐term data of the SIGNS study
Authors: Reiser Marcel , Borte Michael , Huscher Dörte , Baumann Ulrich , Pittrow David , Sommer Claudia , Stangel Martin , Fasshauer Maria , Gold Ralf , Hensel Manfred 
Published: May 2017

AbstractObjectiveWe aimed to describe the current management and outcomes of patients with secondary immunodeficiencies (SID) on intravenous (IV) or subcutaneous (SC) immunoglobulins (IG) as maintenance therapy to prevent infections.MethodsNon‐interventional, prospective study (average follow‐up 20.5 months).ResultsOf the 307 SID patients (mean age 63.7±14.4 years, 52% males, in 31% IG newly initiated), 95.4% received IV IG (mean dosing interval 4.6 weeks, average dose 199 mg/kg per 4 weeks) and 4.6% were treated with SC IG (2.6 weeks, 343 mg/kg per 4 weeks). Median IG through level at first documentation was 5.8 g/L and did not differ between IV and SC treatment or between underlying malignancies. In 24.1% of patients, treatment was interrupted temporarily, over a mean of 11.6±6.3 months. In patients with newly initiated IG treatment the 82% overall infection rate prior to treatment dropped to 21% at 1 year.ConclusionsUnder clinical practice conditions, IG replacement therapy in SID patients was feasible, diminished infection rates and improved quality of life. Average IG doses were relatively low. Tolerability of IV IG treatment was excellent.
Increased harvest of anadromous hatchery steelhead, Oncorhynchus mykiss (Walbaum), through return timing manipulation
Authors: Clarke L. R. , Flesher M. W. , Knox W. J. , Carmichael R. W. 
Published: May 2017

AbstractHarvest hatchery programmes serve to augment fisheries but should also minimise impacts to wild populations. In an experiment to increase harvest in an anadromous hatchery steelhead, Oncorhynchus mykiss (Walbaum), terminal river fishery, a new hatchery strain, was created using selective breeding of early arriving adults to the river. First‐generation progeny of the new early arriving strain were reared and released over 4 years concurrent with releases of the standard hatchery strain. This study compares adult return timing, terminal harvest and straying behaviour of progeny of the early arriving and standard hatchery strains. The new strain migrated towards the terminal river fishery earlier, they were harvested earlier in the eight‐month fishing season and their overall harvest was 17% greater, but 7.7% of the new strain strayed to other rivers compared to 5.0% of the standard strain. Selective breeding to match adult return timing with fishing effort may help bolster harvest, but a paired release evaluation, such as was conducted in this study, would be prudent before switching all hatchery production to a selectively bred strain.
Otolith chemistry indicates walleye movement and entrainment in a large serial reservoir system
Authors: Carlson A. K. , Fincel M. J. , Graeb B. D. S. 
Published: May 2017

AbstractUnderstanding fish movement in impounded river systems is important for fisheries management. Otolith chemistry was used to examine walleye Sander vitreus (Mitchill) intra‐ and inter‐reservoir movement in four Missouri River impoundments. Age‐0 individuals were reclassified with 75%–93% accuracy to known natal sites, allowing for reliable evaluation of movement patterns of age‐1 and older fish. Nearly half of walleye occupied the same location annually (i.e. site residency) between 2009 and 2010. In 2011, during the largest flood on record since 1898, downstream movement (49% of age‐1 and older fish) exceeded upstream movement (7%) and site residency (33%) across the study area. After the flood, most walleye moved downstream within reservoirs (45%) or were site residents (37%). Entrainment occurred most frequently during the flood year and was proportionally greatest in downstream reservoirs. Otolith chemistry is useful for understanding walleye movement and entrainment and is a tool for fisheries management with applications such as informing reservoir water releases, harvest regulations and habitat protection and rehabilitation within and outside the Missouri River reservoir system.
Greater Occipital Nerve Treatment in the Management of Spontaneous Intracranial Hypotension Headache: A Case Report
Authors: Niraj G. , Critchley Peter , Kodivalasa Mahesh , Dorgham Mohammed 
Published: May 2017

BackgroundClinical presentation of spontaneous intracranial hypotension headache (SIHH) has similarities with postdural puncture headache (PDPH). Recommended treatment for both conditions is an epidural blood patch. Successful outcomes following greater occipital nerve blocks have been reported in the management of PDPH. We present the first report of greater occipital nerve treatment in SIHH.MethodsA 40‐year‐old male presented with a 2‐year history of daily postural headaches having a significant impact on quality of life. Magnetic resonance imaging revealed bilateral convexity subdural collections. Post gadolinium scan revealed pachymeningeal enhancement with reduced pontomesencephalic angle below 50 degrees. The patient was offered an epidural blood patch and greater occipital nerve block with corticosteroids. The patient chose occipital nerve block.ResultThe patient reported significant short‐term benefit lasting 4 months. Thereafter, the patient underwent pulsed radiofrequency treatment to bilateral greater occipital nerves. He reported significant benefit lasting 10 months.ConclusionGreater occipital nerve treatment may have a role in management of SIHH.