bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selective data extension for full-waveform inversion: An efficient solution for cycle skipping
Authors: Wu Zedong , Alkhalifah Tariq 
Published: December 2017

Standard full-waveform inversion (FWI) attempts to minimize the difference between observed and modeled data. However, this difference is obviously sensitive to the amplitude of observed data, which leads to difficulties because we often do not process data in absolute units and because we usually do not consider density variations, elastic effects, or more complicated physical phenomena. Global correlation methods can remove the amplitude influence for each trace and thus can mitigate such difficulties in some sense. However, this approach still suffers from the well-known cycle-skipping problem, leading to a flat objective function when observed and modeled data are not correlated well enough. We optimize based on maximizing not only the zero-lag global correlation but also time or space lags of the modeled data to circumvent the half-cycle limit. We use a weighting function that is maximum value at zero lag and decays away from zero lag to balance the role of the lags. The resulting objective function is less sensitive to the choice of the maximum lag allowed and has a wider region of convergence compared with standard FWI. Furthermore, we develop a selective function, which passes to the gradient calculation only positive correlations, to mitigate cycle skipping. Finally, the resulting algorithm has better convergence behavior than conventional methods. Application to the Marmousi model indicates that this method converges starting with a linearly increasing velocity model, even with data free of frequencies less than 3.5 Hz. Application to the SEG2014 data set demonstrates the potential of our method.
Mms19 is a mitotic gene that permits Cdk7 to be fully active as a Cdk-activating kinase
Authors: Nag Rishita Narendra , Niggli Selina , Sousa-Guimarães Sofia , Vazquez-Pianzola Paula , Suter Beat 
Published: December 2017

ABSTRACT
Mms19 encodes a cytosolic iron-sulphur assembly component. We found that Drosophila Mms19 is also essential for mitotic divisions and for the proliferation of diploid cells. Reduced Mms19 activity causes severe mitotic defects in spindle dynamics and chromosome segregation, and loss of zygotic Mms19 prevents the formation of imaginal discs. The lack of mitotic tissue in Mms19P/P larvae can be rescued by overexpression of the Cdk-activating kinase (CAK) complex, an activator of mitotic Cdk1, suggesting that Mms19 functions in mitosis to allow CAK (Cdk7/Cyclin H/Mat1) to become fully active as a Cdk1-activating kinase. When bound to Xpd and TFIIH, the CAK subunit Cdk7 phosphorylates transcriptional targets and not cell cycle Cdks. In contrast, free CAK phosphorylates and activates Cdk1. Physical and genetic interaction studies between Mms19 and Xpd suggest that their interaction prevents Xpd from binding to the CAK complex. Xpd bound to Mms19 therefore frees CAK complexes, allowing them to phosphorylate Cdk1 and facilitating progression to metaphase. The structural basis for the competitive interaction with Xpd seems to be the binding of Mms19, core TFIIH and CAK to neighbouring or overlapping regions of Xpd.
Curcumin and derivatives function through protein phosphatase 2A and presenilin orthologues in Dictyostelium discoideum
Authors: Cocorocchio Marco , Baldwin Amy J. , Stewart Balint , Kim Lou , Harwood Adrian J. , Thompson Christopher R. L. , Andrews Paul L. R. , Williams Robin S. B. 
Published: December 2017

ABSTRACT
Natural compounds often have complex molecular structures and unknown molecular targets. These characteristics make them difficult to analyse using a classical pharmacological approach. Curcumin, the main curcuminoid of turmeric, is a complex molecule possessing wide-ranging biological activities, cellular mechanisms and roles in potential therapeutic treatment, including Alzheimer's disease and cancer. Here, we investigate the physiological effects and molecular targets of curcumin in Dictyostelium discoideum. We show that curcumin exerts acute effects on cell behaviour, reduces cell growth and slows multicellular development. We employed a range of structurally related compounds to show the distinct role of different structural groups in curcumin's effects on cell behaviour, growth and development, highlighting active moieties in cell function, and showing that these cellular effects are unrelated to the well-known antioxidant activity of curcumin. Molecular mechanisms underlying the effect of curcumin and one synthetic analogue (EF24) were then investigated to identify a curcumin-resistant mutant lacking the protein phosphatase 2A regulatory subunit (PsrA) and an EF24-resistant mutant lacking the presenilin 1 orthologue (PsenB). Using in silico docking analysis, we then showed that curcumin might function through direct binding to a key regulatory region of PsrA. These findings reveal novel cellular and molecular mechanisms for the function of curcumin and related compounds.
WORK FAMILY BALANCE – MITO OU APTIDÃO? ESTUDO EMPÍRICO SOBRE OS ANTECEDENTES E AS CONSEQUÊNCIAS
Authors: Pedro Ana Margarida Alexandre , Alcoforado Joaquim Luís M. 
Published: December 2017

O objetivo geral desta investigação consistiu em avaliar um novo modelo conceitual que permitisse inferir variáveis que, embora estudadas, não se enquadravam nos modelos tradicionais da investigação em Work Family Balance. Apresentaram-se diversas variáveis antecedentes e consequentes evidenciadas pela literatura, mas que não haviam sido testadas empiricamente, contribuindo para uma nova visão conceitual do Work Family Balance. O objetivo geral foi propor e avaliar um modelo conceitual de análise que inferisse as variáveis que estariam relacionadas com o Work Family Balance e concluir até que ponto ele interfere na Felicidade Subjetiva, na Performance Individual e no Burnout, de uma amostra de trabalhadores portugueses. A metodologia quantitativa aplica inquéritos, por meio de questionários, a uma amostra de trabalhadores portugueses. As hipóteses corroboradas foram: Inteligência Emocional (parcialmente), Workaholism, Reward System e Valores Éticos Corporativos, como antecedentes e Felicidade Subjetiva, Performance Individual e Burnout (parcialmente) como consequentes.
Infective endocarditis today
Authors: D'Agostino Donato 
Published: December 2017

Endocarditis is an infectious disease caused by numerous microorganisms, many of which habitually colonize the oral cavity and skin. Various bacteria and bacterial factors influence the duration of bacteremia and the possible colonization of cardiac valves. If not recognized and treated early, the disease may have serious consequences until death: despite the possibility of setting up targeted antibiotic therapy, it may occur in 30% of cases. This event is related to sepsis that develops in these patients and can result in cellular functional alterations in many districts, resulting in multi-organ failure (MOF) status. This paper is aimed to present an overview of this condition, based on the author’s own clinical experience and literature review.
Rationale and design of a multi-center, open-label, randomised clinical trial comparing HIV incidence and contraceptive benefits in women using three commonly-used contraceptive methods (the ECHO study)
Authors: Hofmeyr G. Justus , Morrison Charles S. , Baeten Jared M. , Chipato Tsungai , Donnell Deborah , Gichangi Peter , Mugo Nelly , Nanda Kavita , Rees Helen , Steyn Petrus , Taylor Douglas ,   ECHO Trial Team
Published: December 2017

Background: In vitro, animal, biological and observational clinical studies suggest that some hormonal methods, particularly depot medroxyprogesterone acetate – DMPA, may increase women’s risk of HIV acquisition. DMPA is the most common contraceptive used in many countries worst affected by the HIV epidemic. To provide robust evidence for contraceptive decision-making among women, clinicians and planners, we are conducting the Evidence for Contraceptive Options and HIV Outcomes (ECHO) study in four countries with high HIV incidence and DMPA use: Kenya, South Africa, Swaziland, and Zambia (Clinical Trials.gov identifier NCT02550067). Study design: We randomized HIV negative, sexually active women 16-35 years old requesting effective contraception and agreeing to participate to either DMPA, the copper T 380A intrauterine device or levonorgestrel implant. Participants attend a contraception support visit after 1 month and quarterly visits thereafter for 12 to 18 months. Participants receive a standard HIV prevention package and contraceptive side-effect management at each visit. The primary outcome is HIV seroconversion. Secondary outcomes include pregnancy, serious adverse events and method discontinuation. The sample size of 7800 women provides 80% power to detect a 50% difference in HIV risk between any of the three method pairs, assuming 250 incident infections per comparison. Ethical considerations: Several WHO consultations have concluded that current evidence on HIV risk associated with DMPA is inconclusive and that a randomized trial is needed to guide policy, counselling and choice. Previous studies suggest that women without a specific contraceptive preference are willing to accept randomization to different contraceptive methods. Stringent performance standards are monitored by an independent data and safety monitoring board approximately every 6 months. The study has been conducted with extensive stakeholder engagement. Conclusions: The ECHO study is designed to provide robust evidence on the relative risks (HIV acquisition) and benefits (pregnancy prevention) between three effective contraceptive methods.
Os guerreiros do imaginário: Entrevista de Abdellatif Chaouite com Patrick Chamoiseau
Authors: Brun Milenna , Brun Eric 
Published: December 2017

Tradução de uma entrevista com Patrick Chamoi­seau, por Abdellatif Chaouite realizada na ação « Fazer o mundo com o Outro », iniciada pela Maison des Passages (Lyon) no contexto do Contrato Urbano de Coesão Social, publicada no periódico Ecarts d'identité, Grenoble: n°112, p. 25-34, junho, 2008.
Play like Jay: Pedagogies of drum kit performance after J Dilla
Authors: Stadnicki Daniel Akira 
Published: December 2017

Abstract
This article explores the legacy of hip-hop producer J Dilla (1974–2006) through examining his impact on live drum kit performance and pedagogy. Specifically, it addresses how the so-called ‘Dilla-feel’ is emulated by drummers and rhythm section players through a range of informal learning strategies and extended techniques, which include practices of online teaching and learning. Closely associated with the neo-soul movement of the late 1990s and early 2000s, J Dilla’s musical contributions have often gone overlooked, despite being essential for the development of the characteristic, lilting time-feel heard on many of these recordings. Incorporating historical, ethnographic and performance-based approaches, the study outlines how hip-hop’s sample-based aesthetic has dramatically shaped live musicianship on more traditional instruments, focusing on the significance of J Dilla’s drum programming in contemporary popular musicianship.
Examining music teachers’ experiences in a rock band performance and pedagogy professional development course
Authors: Dorfman Jay 
Published: December 2017

Abstract
Using a framework of transformation in schools that may result from teachers’ professional development, this study documented five music teachers’ experiences in a professional development course about performing in and teaching rock bands. Research questions focused on examining the participants’ experiences and recognizing influences from the course that might lead to change in the participants’ teaching after the class. Findings centred on rehearsal experiences, emergence of leadership, changes in attitudes about music styles and evidence of continued participation in rock music. As suggested in other studies of professional development experiences, the students enjoyed the class because they felt it was relevant, it addressed student learning and it contributed to their development as teachers. The students drew on their own backgrounds as leaders and learners in order to transition to the role of teacher of popular music.
An investigation of attitudes of 10-12 year-old students enrolled in public and private schools towards physical education course <p>Devlet okulu ve özel okulda okuyan 10-12 yaş grubu öğrencilerin beden eğitimi ve spor dersine karşı tutumlarının incelenmesi
Authors: Özsarı İsmail 
Published: December 2017

The aim of this study is to investigate whether there are any difference in 10-12-year-old students’ attitudes towards physical education course according to school types (public school/private school). The survey method was used in the study. The sample consisted of 185 students from two public schools and two private schools. 119 students were enrolled in public school while 66 students were in enrolled in private school. As data collection tools, a 24-item questionnaire to obtain sport activities students participate, the resources they have, and their demographic information; and a likert-type, 49-items "Physical Education Course Attitude Scale" to assess their attitudes towards physical education course were used. The scale was developed by Sherrill and Toulmin in 1977 and adapted by Özer and Aktop into Turkish in 2003. The data were analyzed using SPSS 20.0 software, findings were presented in frequency-percentage tables, and independent group t-test and chi-square test were used. According to findings, students of private schools had significantly more positive attitudes towards the physical education course than students of public schools.Extended English abstract is in the end of Full Text PDF (TURKISH) file.ÖzetBu çalışma 10-12 yaş grubu öğrencilerinin okudukları okul türü değişkenine (devlet okulu/özel okul) göre Beden Eğitimi ve Spor dersine karşı tutumlarında farklılık olup olmadığını ortaya koymayı amaçlamaktadır. Araştırmada betimsel tarama modeli kullanılmıştır. Örneklem grubunu İstanbul ilindeki ikisi devlet okulu, ikisi özel okul olmak üzere dört farklı okulda öğrenim gören toplam 185 öğrenci oluşturmaktadır. Öğrencilerden 119’u devlet okulunda, 66’sı özel okulda öğrenim görmektedirler. Veri toplama aracı olarak öğrencilerin demografik bilgileri, yaptıkları spor faaliyetleri ve sahip oldukları olanakları yansıtan 24 maddelik anket ve Beden Eğitimi ve Spor dersine karşı tutumlarını ölçmek amacıyla 49 maddelik, 7’li likert tipindeki “Beden Eğitimi Dersi Tutum Ölçeği” uygulanmıştır. Ölçek 1977 yılında Sherrill ve Toulmin tarafından geliştirilmiş, Özer ve Aktop tarafından 2003 yılında Türkçe’ye uyarlanmıştır. Elde edilen veriler SPSS 20.0 programı ile analiz edilmiş, bulgular frekans-yüzdelik tabloları şeklinde sunulmuş ve bağımsız grup t-testi ki-kare testi teknikleri kullanılmıştır. Araştırmanın sonucunda özel okulda okuyan öğrencilerin Beden Eğitimi ve Spor dersine ilişkin tutumlarının, devlet okulunda okuyan öğrencilere göre anlamlı derecede daha olumlu olduğu ortaya çıkmıştır.
Gallstone Ileus Caused by a Cholecysto-Duodeno-Colic Fistula, Case Report And Literature Review
Authors: Suciu B. A. , Hălmaciu Ioana , Vunvulea V. , Trâmbițaș C. , Pisică R. , Lata Laura , Fodor D. , Molnar C. , Copotoiu C. , Brînzaniuc Klara 
Published: December 2017

Abstract
Introduction: Complex cholecysto-duodeno-colic fistulas are an extremely rare complication that can occur in patients with cholelithiasis. The aim of this article is to present the case of a pacient with cholecystoduodeno- colic fistula manifested with biliary ileus in a patient known for many years with cholelithiasis. Case report: We present the case of a 62 y/o male that was admitted in our clinic with the diagnosis of gallstone ileus. Emergency surgical intervention was needed. Intraoperatively we discovered a cholecysto-duodenocolic fistula complicated with gallstone ileus. During the operation we practiced retrograde cholecystectomy, closure of the fistulous tract (duodenoraphy, coloraphy), enterotomy and extraction of the calculus located inside the small intestine. The postoperative evolution was favorable. Conclusions: Cholecysto-duodeno-colic fistulas complicated with gallstone ileus are an extremely rare complication that can occur in patients with gallstones. In case of the occurrence of gallstone ileus, the surgical treatment is an emergency, being the only therapeutic technique that can save the patient’s life.
Enterovirus Meningitis in Children from Constanta
Authors: Bolojan Bianca Mihaela , Cambrea Simona Claudia 
Published: December 2017

Abstract
Introduction: Many different viruses can cause meningitis. Most children are exposed to some of them during their life without developing meningitis. Of all the viruses, enteroviruses are the most frequent involved in etiology of meningitis. Material and Method: The evaluated group consisted of 73 patients, boys and girls aged 1 to 12 years, hospitalized at Constanta Clinical Infectious Diseases Hospital during the period May 2016 - October 2017. Results: Over the studied period, 243 patients were admitted with suspicion of meningitis, but just 73 of them were confirmed (30.04%). The average age of children with Viral Meningitis was 5 years and 8 months old, with a gender distribution that revealed a 2:1 balance in boy’s favor. The most affected age groups were 1-3 years and 4-6 years with 27 cases each. Fever, headaches and vomiting were the most common symptoms, occurring in majority of the patienst (53/73). Cerebrospinal fluid was clear in 58 cases, meanwhile in 15 cases the fluid was opalescent. Polymerase chain reaction on cerebrospinal fluid revealed Enterovirus in 27 out of the 73 cases. Conclusions: Viral meningitis with enteroviruses should be considered in any paediatric patients admitted with fever, headaches and vomiting, boys and girls, due to the potential outbreaks that can appear during the summer or autumn.
Bird Communities and Vegetation Composition in the Urban Forest Ecosystem: Correlations and Comparisons of Diversity Indices
Authors: Blinkova Olena , Shupova Tetyana 
Published: December 2017

AbstractAssessment of relationships and diversity indices between bird’s communities and composition of the forest ecosystem is an important subject of synecological research to identify the intensity of human impact on the flora and fauna. Urban recreation is one of the major causes of violation of the structural and functional integrity of the forest ecosystem. Studies of avian complex and phytocoenosis have focused on the impact of urban recreation on the compositions of tree, shrub and herbaceous layers and species, trophic and ecological compositions of breeding-birds and feeding-birds communities. This paper compares the measurement of the diversity of bird communities and forestry vegetation (diversity indices, dominance indices, distribution uniformity indices) of intensive, medium, moderate and weak stages of recreational transformation of biotope. The stands formed Quercus robur L., Carpinus betulus L., Acer platanoides L., Tilia cordata L. The floristic list comprised 78 grass species. A total number of 43 species of avifauna including 37 breeding species are observed during the study. There were significant correlations between vertical heterogeneity of tree distribution and abundance, species richness and nesting density of birds. The interrelationship between species diversity of birds and floristic richness was also confirmed.
Performance and Kinematic Differences in Putting Between Healthy and Disabled Elite Golfers
Authors: Gryc Tomáš , Stastny Petr , Zahálka František , Smółka Wojciech , Żmijewski Piotr , Gołaś Artur , Zawartka Marek , Malý Tomáš 
Published: December 2017

Abstract
Golfers with disability are limited in the execution of the full golf swing, but their performance in putting may be comparable because this stroke does not demand significant strength, balance and range of motion. Therefore, the aim of this study was to compare putting performance, kinetic and kinematic consistency between golfers with different disabilities and healthy athletes. The participants consisted of three disabled athletes (perinatal cerebral palsy, multiple sclerosis, below knee lower limb amputee) and three healthy golfers (age 34 ± 4.5 years, body height 178 ± 3.3 cm, body mass 83 ± 6.2 kg). The golfers’ movements were recorded by active 3D markers for kinematic analyses; the subjects performed 10 trials of a 6 m putting task while standing on separate force platforms placed under each lower limb. Putting performance was measured by the distance of the final ball position to the centre of the hole. ANOVA analyses did not show any differences in clubhead speed and total ball distance from the hole. The consistency of those two parameters expressed by the coefficient of variation (CV) was CV = 0.5% or better in both groups for clubhead speed and ranged from CV = 0.40 to 0.61% in healthy and CV = 0.21 to 0.55% in disabled athletes for total error distance. The main effect ANOVA showed differences in weight shift, hip and shoulder kinematics (p < 0.05) between healthy players and all players with disability. All disabled athletes shifted their weight toward the healthy side (towards the healthy lower limb) and alternated the end of the swing. The player with below knee amputation had the lowest range of motion in the shoulder joint during the putting stroke. The players with perinatal cerebral palsy and multiple sclerosis had the largest range of motion in the hips. Putting performance of disabled golfers was similar to healthy athletes. During training of disabled players, coaches should pay attention to the specificity of a particular disability when focused on putting performance. However, individual technique should achieve the same consistency as observed in healthy players.
Validation of large scale noise exposure modelling by long-term measurements
Authors: Schlatter Felix , Piquerez A. , Habermacher M. , Ragettli M. S. , Röösli M. , Brink M. , Cajochen C. , Probst-Hensch N. , Foraster M. , Wunderli J.-M. 
Published: December 2017

Abstract
Large scale noise exposure modelling is used in epidemiological research projects as well as for noise mapping and strategic action planning. Such calculations should always be accompanied by an assessment of uncertainty, on the one hand to check for systematic deviations and on the other hand to investigate the sources of uncertainty to address them in future studies. Within the SiRENE (Short and Long Term Effects of Transportation Noise Exposure) project, a large scale nationwide assessment of Switzerland’s road, railway, and aircraft noise exposure was conducted for the year 2011. In the present follow-up study, we equipped 180 sleeping and/or living room windows with sound level meters for one week. The resulting dataset was used to validate noise exposure modelling within SiRENE. For the noise metric LDEN the comparison revealed a difference of 1.6 ± 5 dB(A) when taking all measurements into account. After removing measurement sites with noise mitigation measures not considered in the modelling, the difference to the calculation was reduced to 0.5 ± 4 dB(A). As major sources of uncertainty, the position accuracy and topicality of infrastructure and building geometries, the traffic modelling as well as the acoustic source and propagation models were identified.