bluuebunny/crossref_metadata_2025_split huggingface dataset:
Le « Cahier de Verson »dans la genèse des Chants pour Naëttpuis des « Chants pour Signare »
Authors: Meitinger Serge 
Published: October 2024

C’est un cahier d’écolier extrait des archives laissées à Verson par le poète-président. Il contient, à une exception près, l’intégralité des Chants pour Naëtt (1949) qui seront ensuite les « Chants pour Signare » de Nocturnes (1961) et huit poèmes de plus qui trouveront place dans Éthiopiques (1956). Moins un brouillon stricto sensu qu’une première mise au net, il permet d’intéressantes analyses génétiques qui révèlent les subtilités du tissage des textes : hésitations entre plusieurs termes, enrichissement de l’expression et des références, travail sur la structure syntaxique et le déroulé du poème. Un groupe de poèmes, le « Chant de l’initié », pose un problème spécifique, celui de son appartenance à l’ensemble, tout comme de son emplacement dans le recueil. Quelle fut l’intention du poète en le tenant ainsi à la lisière de la première grande section de Nocturnes ?
An alternative look at John 14:6
Authors: Oliver Willem H. 
Published: October 2024

This article takes an alternative look at John 14:6 in its pericope John 14:1–14 as part of Jesus’ Farewell Discourse to his disciples (Jn 13–17). This verse forms part of the seven ‘I am’ sayings in the Gospel of John. Traditionally the two καί terms in John 14:6 are translated with ‘and’ I am the way and the truth and the life. However, this article opts for the epexegetical or explicative (also called explanatory) way to translate καί. The reason is that the focus of this pericope and specifically this verse is on ὁδός, and not like the traditional translations treat all three terms, ὁδός, ἀλήθεια and ζωή on an equal basis.Intradisciplinary and/or interdisciplinary implications: This is a New Testament piece of research that interacts and intersects with Dogmatic and Practical Theology, and the traditional interpretation of the text of John 14:6. It is therefore more intradisciplinary than interdisciplinary by nature.
Human papillomavirus carriage in the semen of men consulting for infertility: prevalence and correlations with sperm characteristics
Authors: Priam Armin , Bozec Antoine Le , Meireles Vasco Dias , Saint Fabien , Cabry Rosalie , Benkhalifa Moncef , Demey Baptiste , Bosquet Dorian 
Published: October 2024

Abstract
We aim to study the semen carriage of human papillomavirus (HPV) and evaluate its association with patient characteristics. We conduct a single-center cohort study at Amiens University Hospital Center (Amiens, France). From May 1 to October 31, 2021, 461 men consulting for infertility and with semen analysis data were included. Each participant gave his written informed consent for the use of laboratory, demographic, clinical, and lifestyle data. A proportion of the semen samples were sent to a virology laboratory for HPV screening in a polymerase chain reaction (PCR) assay. In univariate and multivariate analyses with a logistic regression model, HPV+ and HPV− groups were compared with regard to semen characteristics (including the DNA fragmentation index and the sperm decondensation index) and demographic, clinical, and lifestyle variables. Semen HPV carriage was detected in 22.3% of the patients. High-oncogenic-risk HPV genotypes were predominant (57.6%). Multivariate analysis showed that HPV carriage was significantly associated with the presence of at least one abnormal spermogram dinging (according to the 6th World Health Organization criteria), with an adjusted odds ratio (OR) of 4.10 (95% confidence interval [CI]: 2.32–7.25, P < 0.001). A statistically significant association was also found for the type of infertility (OR: 1.61, 95% CI: 1.00–2.57, P = 0.05), the presence of varicocele (OR: 3.99, 95% CI: 1.48–10.71, P = 0.01), and a history of cryptorchidism, testicular ectopia, or monorchidism (OR: 3.54, 95% CI: 1.07–11.66, P = 0.04). Infection with a single HPV genotype or multiple HPV genotypes was significantly associated with at least one abnormal spermogram finding for all HPV oncogenic risk groups (OR: 3.93, 95% CI: 2.08–7.41, P < 0.001; and OR: 4.11, 95% CI: 1.58–10.68, P = 0.01, respectively). The association between sperm HPV carriage and the risk of infertility was statistically significant in a multivariate analysis (OR: 5.63, 95% CI: 3.16–10.01, P < 0.001) and after adjustment for the propensity score (OR: 6.10, 95% CI: 3.33–11.21, P < 0.001). Our results suggest that semen HPV carriage has an impact on male fertility. Sperm screening for HPV might be a useful addition to the work-up for male infertility.
Hypogonadotropic hypogonadism as a cause of NOA and its treatment
Authors: Salvio Gianmaria , Balercia Giancarlo , Kadioglu Ates 
Published: October 2024

Abstract
Hypogonadotropic hypogonadism (HH) represents a relatively rare cause of nonobstructive azoospermia (NOA), but its knowledge is crucial for the clinical andrologists, as it represents a condition that can be corrected with medical therapy in 3 quarters of cases. There are forms of congenital HH, whether or not associated with an absent sense of smell (anosmic HH or Kallmann syndrome, and normosmic HH, respectively), and forms of acquired HH. In congenital HH, complete absence of pubertal development is characteristic. On the other hand, if the deficit occurs after the time of pubertal development, as in acquired HH patients, infertility and typical symptoms of late-onset hypogonadism are the main reasons for seeking medical assistance. Gonadotropin-releasing hormone (GnRH) or gonadotropin replacement therapy is the mainstay of drug therapy and offers excellent results, although a small but significant proportion of patients do not achieve sufficient responses.
Higher toll-like receptor 3 expression in umbilical cord blood B cells than in adult blood B cells
Authors: Khalil Sohaila M. , Askar Menna , Abduljalil Shimaa M. , El Naggar Randa Ezz-Eldin , Salem Mohamed L. 
Published: October 2024

Background
Umbilical cord blood (UCB), which is considered a rich source of stem cells, has been used for applications in different clinical settings. Therefore, it is crucial to examine the toll-like receptor (TLR) expression levels in UCB B cells as compared to adult blood cells.

Aim
To determine the phenotypes of B cells in UCB and to investigate their expression of TLR3 as compared to adult blood.

Patients and methods
Samples of UCB were collected (n=20) after delivery, and peripheral blood samples were collected from female healthy volunteers (n=10) in K2EDTA tubes. Cells were washed twice, then stained using anti-CD19 and anti-TLR3. The samples were acquired by flow cytometry to assess the phenotype of B cells and their expression of TLR3. Besides, the liver and kidney functions were assessed.

Results
The relative number of CD19+ cells showed lower numbers (5.35%) in UCB than adult blood (15.64%). Additionally, the absolute number of CD19+ cells showed lower numbers by two-fold in cord blood than in adult blood. The relative expression of TLR3 on CD19+ cells showed lower expression in UCB as compared to adult blood by 5.8-fold. However, the absolute number of TLR3+CD19+ was higher in UCB than in adult blood by two-fold. The liver and kidney function showed normal values as investigated the enzyme activity of aspartate aminotransferase, alanine aminotransferase, bilirubin, and creatinine in both cord and adult.

Conclusion
B cells express lower TLR3 in cord blood than in adult blood. The data from this study open new avenues for the manipulation of cord blood by TLR agonists for clinical application.
Comparative Analysis of Adaptation of Conventional and Printable Complete Denture Bases to the Underlying Casts - An In vitro Stereomicroscopic Study
Authors: Sinha Divyansh , Lakkoji Keerthi Sasanka , Faiz Nadhirah 
Published: October 2024

Abstract

Introduction:
Properly adapted complete denture bases will have adequate retention to the underlying oral mucosa. With technological advancement, there are various techniques of fabrication of complete dentures. There are studies regarding the marginal adaptation of conventional and CAD-CAM denture bases, but there is not enough research comparing the marginal adaptation and polymerisation shrinkage of conventional and 3D printed complete denture bases.

Study Setting and Design:

In vitro study using stereomicroscopy to determine the marginal discrepancy between the denture base and the cast.

Materials and Methods:
Twelve gypsum casts were taken and divided into conventional and 3D-printed groups. Conventional denture bases were fabricated by adapting wax of 2 mm thickness which was subsequently processed whereas 3D printed bases were designed and the standard tessellation language (STL) files were used to print the denture bases. Three points were marked at the mid-palatal line and on both maxillary tuberosities. Digital images were then captured at the marked regions and were used to measure the maximum gap between the cast and denture base at the marked regions. Data were analysed using an independent t-test and one-way ANOVA.

Results:
Conventional dentures had a significantly lesser marginal discrepancy than 3D printed dentures (P = 0.000). The left maxillary tuberosity showed the highest marginal discrepancy, significantly different from mid-palatal and right tuberosity sites.

Conclusion:
Conventional dentures perform better than their counterparts in terms of adaptation. This accurate adaptation is vital for the retention of the complete denture.
Eye of the Beholder: Prevalence of Binge Eating Disorder among Youth in Urban Coastal Karnataka, India
Authors: Varadarajulu Rachel Natasha , Muddasani Varsha , Prabhu H. Sudhir , Thattil Anissa Mary Thomas 
Published: October 2024

Abstract

Introduction:
Eating disorders (EDs) are on the rise and can result in medical and psychiatric morbidities in children, adolescents as well as during adulthood. It is crucial to understand the disease burden for its early diagnosis, intervention, and prevention. Our study was thus conducted over 5 months to estimate the prevalence of binge ED (BED) among adolescents and young adults in Mangalore, Karnataka.

Materials and Methods:
A total of 300 participants between the ages of 15 and 24 years were administered the Questionnaire on Eating and Weight Patterns - 5. Responses were categorized into “possible diagnosis of BED” and “possible diagnosis of bulimia nervosa (BN).”

Results:
The mean age of the participants was 19.4 ± 3.1 years and their mean body mass index was 22.7 ± 3.9 kg/m2. Among 300 participants, 15 (5.0%) had a possible diagnosis of BN, while 4 (1.3%) had a probable diagnosis of BED, both were found to be more among females than males. Sixty participants reported having loss of control over their food intake, of which only 26 (43.3%) reported being upset about it. However, on multivariate logistic regression, none of the sociodemographic factors were found to be significant in our study.

Conclusion:
It is essential to encourage healthy eating habits and physical activity at an early age along with the inclusion of screening for EDs in school health programs. Raising awareness among parents and children is crucial in bringing about sustained behavior change.
Experiences and Perspective of Caretakers Working in Childcare Institutes in Delhi: A Qualitative Inquiry
Authors: Sharma Prerna , Sharma Yashika 
Published: October 2024

Abstract

Context:
Institutional care is a common alternative for children who have been displaced from their homes due to a variety of socioeconomic factors. The quality of care and well-being of children in such institutions has been under research due to its long-lasting impacts on a child’s early development. However, the perspective of caregivers who are an important point of contact with the children is yet to be explored thoroughly.

Aim:
The current study aims to understand the experiences of caregivers in childcare institutes (CCIs) through a qualitative lens of inquiry.

Settings and Design:
The study has employed a qualitative, exploratory, inductive research design.

Methodology:
A semi-structured focus group discussion (FGD) schedule was developed, and FGDs were held with caregivers across seven CCIs in five districts of New Delhi.

Qualitative Analysis:
Using analysis software (QSR NVIVO 10), thematic analysis was conducted in two stages, namely, initial coding and focused coding to organize the data into meaningful themes.

Results:
The thematic analysis revealed a set of 4 main themes, 13 subthemes, and more than 200 codes emerging from the qualitative dataset. The themes threw light on key challenges and concerns that caretakers of children in institutional care often face. The caretakers’ current knowledge of psychological concerns and the gap in providing psychologically informed care for children is emphasized.

Conclusion:
The study highlights some key beliefs, such as stigma regarding mental health concerns and perceptions about their work as a “duty.” In addition, knowledge among caregivers about specific psychological issues such as self-harm and aggression may influence caring for children. Furthermore, prominent skillset challenges such as the management of children with emotional and behavioral concerns, and children with disability were highlighted. The findings reveal that the caregivers experience workplace burden due to a lack of adequate resources and specialized knowledge in childcare.
Graft Maturity Assessment by Magnetic Resonance Imaging and its Relation with Functional Scores after Anterior Cruciate Ligament Reconstruction with Hamstring Graft
Authors: Arun G. R. , Rao Manohar , Patil Neelanagowda , Srinivasan Namrata , Krishnan P. Rahul , Deepak M. K. , Sindhu B. 
Published: October 2024

Abstract

Background/Objectives:
Anterior cruciate ligament (ACL) reconstruction is a common procedure performed in orthopedic surgery. There are many methods to evaluate the functional outcome postoperatively, but no single reliable method exists to assess graft maturity. The purpose of this research is to evaluate graft maturity by magnetic resonance imaging (MRI) and its relation with functional outcome at the end of 6 months and 12 months.

Materials and Methods:
MRIs were performed on 32 patients who underwent ACL reconstruction at 6 and 12 months following surgery. The measurements were made of the background, posterior cruciate ligament, and signal intensity of the graft. The calculation of the signal noise quotient (SNQ) was done. The correlations between the international knee documentation committee (IKDC) at 6 and 12 months and the SNQ values at 6 and 12 months were assessed.

Results:
After 6 months, the mean SNQ value was 3.8953 ± 2.6561, and after 12 months, it was 2.6013 ± 1.7337. In addition, the mean IKDC was 43.3 preoperatively, 52.8125 ± 9.24728 at 6 months’ follow-up and 70.6875 ± 8.32578 at 12 months’ follow-up. The 12-month SNQ values showed a significant decrease, according to RMANOVA (F[1,62] = 6.50871, P = 0.01316). Conversely, the IKDC scores at 12 months demonstrated a statistically significant rise (F[1,62] = 66.03667, P < 0.001).

Conclusion:
MRI is a reliable investigation to assess the graft maturity. In our study, hamstring graft demonstrated superior maturity at 12 months as compared to 6 months’ postsurgery. There was a noteworthy inverse relationship between graft SNQ and IKDC scoring. MRI assessment at 6 months and 12 months is desirable to know graft’s maturity and helps to modify the rehabilitation protocol.
Evaluation of Return to Military Activities after Combining Anterior Cruciate Ligament Reconstruction with Modified Lateral Extra-articular Tenodesis Versus Anterior Cruciate Ligament Reconstruction Alone in Primary Anterior Cruciate Ligament Tear in Soldiers. A Randomized Comparative Study
Authors: Gupta T. P. , Rai S. K. , Sirohi Bhavya , Kale Amit , Kashid Manoj , Negi R. S. 
Published: October 2024

Abstract

Background:
This study aimed to assess the clinical result, complications, failure rate, and return to resuming military duty of a single-stage anterior cruciate ligament reconstruction (ACLR) procedure utilizing quadrupled semitendinosus tendon graft joint with modified lateral extra-articular tenodesis (LET). This study evaluates the potential impact of combined modified LET with ACLR versus ACLR alone on the rate of return to high-impact military activities, which we call return to sports (RTSs), and the subsequent rate of the anterior cruciate ligament (ACL) graft failure.

Materials and Methods:
A total of 198 soldiers with primary ACL tears with a high-grade pivot test (grade 3) were included and randomized using the simple randomized method and divided into two groups. A consecutive cohort of military personnel with an isolated ACL tear undergoing ACLR with modified LET (group A, n = 116) and ACLR alone (group B, n = 82) were analyzed between 2016 and 2021. Both groups were followed up for a minimum of 2 years. Soldiers underwent a survey evaluating knee function (knee injury and osteoarthritis outcome score [KOOS]), RTS criteria (RTS type), symptoms (International Knee Documentation Committee [IKDC] subjective), activity level (Tegner score), and fear of movement (Tampa Scale of Kinesiophobia-11) to assess psychological readiness for sport participation.

Results:
Among these, a mean age of 32 ± 2.93 years underwent primary ACLR with modified LET (n = 116) or without LET (n = 82) procedure. A total of 31 soldiers (15.6%) experienced ACL graft failure, including 26 (31.7%) reconstructions without LET and 5 (4.3%) with LET. Combined with LET during primary ACLR, it lowered the risk of graft failure by 2.8 times. Multivariable analysis revealed a significant reduction in graft rupture risk (relative risk = 0.325, P = 0.029) associated with LET compared to ACLR alone after adjusting for age, anthropometric factors, and tibial slopes. 105 out of 113 (90.5%) soldiers were able to return to military duty in group A (combined ACLR with modified LET), whereas 51 of 81 (62.9%) of the soldiers who underwent ACLR alone (group B) returned to military duty (P = 0.05).

Conclusion:
At 24 months postoperatively, combined ACLR plus LET showed a significantly higher RTS rate than ACLR alone. The combined ACLR with the modified LET group also showed a lower failure rate than the ACLR alone group. No marked differences were observed in KOOS sub-scores, IKDCsubjective, and Tegner activity scores.
Lethal Complication of Postairway Stenting to Trachea and Left Main Bronchus: A Case Series with Discussion of the Diagnosis and Management
Authors: Lin Cheng-Jung , Huang Tsai-Wang , Pu Ta-Wei , Lin Kuan-Hsun 
Published: October 2024

Abstract
The insertion of a metallic airway stent is a valuable method for the treatment of benign and malignant airway stenosis and tracheoesophageal fistula. Although stenting for airway stenosis has become widely popular with favorable outcomes, several complications can arise after stenting, such as migration, tendency for stent fracture, and ingrowth of tumor or granulation tissue into the stent. Very few of these reports have described the complications of poststenting pneumothorax. We report the cases of three patients diagnosed with squamous cell carcinoma of the esophagus, complicated by tracheoesophageal fistula, and treated with a tracheal stent or bronchial stent, who developed poststenting pneumothorax.
Relationship of Serum Vitamin D Levels to the Severity of Migraine
Authors: Ozomma Simon Izuchukwu , Oparah Sidney Kelechi , Danesi Mustapha Abudu , Ojini Francis Ibe , Anyanwu Roosevelt Amaobichukwu 
Published: October 2024

Abstract

Background:
Most studies done on Vitamin D deficiency in migraine focused more on headache frequency than intensity and severity of the condition. This study is aimed at determining the relationship between serum Vitamin D levels and severity of migraine in a Nigerian setting.

Materials and Methods:
Using a cross-sectional analytical study design, adult patients with migraine consecutively attending the neurology clinic at the Lagos University Teaching Hospital, were recruited on fulfilling the study criteria. Their age- and sex-matched healthy headache-free controls were also recruited. Demographic information and clinical parameters were obtained with an interviewer-administered questionnaire. Headache severity and pain intensity were documented using incorporated headache disability index (HDI) and numerical rating scale (NRS) tools, respectively. Serum levels of Vitamin D, calcium and albumin were assayed for all study participants.

Results:
The participants comprised 35 migraine and 50 control subjects. The migraine subjects comprised 10 males and 25 females, with mean ages of 29.4 ± 9.3 and 40.0 ± 11.1 years respectively (P = 0.01). The mean serum Vitamin D levels among migraine and control participants were 43.45 ng/ml ± 16.84 and 48.78 ng/ml ± 23.33, respectively (P = 0.31). The mean NRS was 7.3 ± 1.2 while the mean HDI was 44.7 ± 19.1 among migraine patients. There was no significant correlation between serum Vitamin D levels and pain intensity (r = 0.29, P = 0.9), and no correlation with HDI (r = 0.004, P = 0.96).

Conclusion:
The serum Vitamin D levels among migraine and control participants were not significantly different. No significant relationship was found between serum Vitamin D level and headache severity index or pain intensity in migraine patients.
Health-care Utilisation among Elderly People with Chronic Medical Conditions in a Secondary Health-care Center, Southwestern Nigeria
Authors: Akingunola Olumuyiwa , Sogunle Taiwo , Kareem Yessir , Egua Lydia 
Published: October 2024

Abstract

Background:
The elderly population of the world is projected to continue to increase. There is an anticipated increase in the utilisation of health-care services due to chronic diseases and other impairments with resulting pressure on health systems.

Aims:
This study aimed to determine the health-care utilisation of elderly patients with chronic medical diseases attending a secondary health facility in southwestern Nigeria.

Materials and Methods
A structured questionnaire was administered to gather the data from 300 older people by random sampling during follow-up care for those receiving care for more than 6 months following a diagnosis of a chronic disease. SPSS software version 26 was used for the data analysis, and the results are presented in the tables. The Chi-square test was applied to test for associations between the categorical variables, and a logistic regression model was used to rule out confounders, while P < 0.05 was considered to indicate statistical significance.

Results:
The mean age (standard deviation) in the study was 68.26 (7.01) years and 58.3% were females. The average number of routine clinic visits was 4.12, whereas 20.7% had emergency room visits, 6.6% were referred to specialists, and 33.3% had laboratory investigations. After logistic regression was applied, living conditions, average monthly income, and treatment for diabetes were found to be significant factors for the utilisation of care.

Conclusion:
The provision of rich social support, improving economic empowerment, and performing screening and timely management for diabetes will improve preventive care while reducing the use of expensive and specialised care for older people.