bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Plasma-Based, Amiodarone-Impregnated Material Decreases Susceptibility to Atrial Fibrillation in a Post–Cardiac Surgery Model
Authors: Schwartzman David , Badhwar Vinay , Kormos Robert L. , Smith Jason D. , Campbell Phil G. , Weiss Lee E. 
Published: February 2016

Objective This study aimed to test the impact of a plasma-based, material (PBM) impregnated with amiodarone on atrial electrophysiology and atrial fibrillation susceptibility in a porcine post–cardiac surgery model. Methods Ten healthy pigs underwent implantation of transvenous pacing systems, after which sterile talc was infused into the pericardial sac via a pericardiotomy. In five animals, PBM was applied to the atrial epicardial surface just before talc infusion. Electrophysiologic evaluations were performed using the pacing system immediately after chest closure and 7 days later. Atrial histologic evaluations were performed. Results Immediately after chest closure, there were no significant differences in electrophysiologic parameters between talc-only and talc + PBM animals, and atrial fibrillation was largely noninducible. On postsurgical day 7, electrophysiologic evaluation revealed significantly shorter sinus cycle length and atrioventricular nodal refractoriness among talc-only animals relative to talc + PBM animals, possibly suggesting attenuated sympathetic nervous system activation in the latter. Atrial fibrillation inducibility and duration were significantly greater among talc-only animals. No significant differences in atrial refractoriness or conduction time between groups were apparent. Histologic evaluation revealed a relative reduction in epicardial inflammation and less myolysis among talc + PBM animals. Conclusions Epicardial application of a plasma-based, amiodarone-impregnated material was associated with a significant reduction in atrial inflammation and susceptibility to fibrillation.
Comparative Performance of Diagnosis-based and Prescription-based Comorbidity Scores to Predict Health-related Quality of Life
Authors: Mehta Hemalkumar B. , Sura Sneha D. , Sharma Manvi , Johnson Michael L. , Riall Taylor S. 
Published: February 2016

Objectives:
To compare the performance of the health-related quality of life-comorbidity index (HRQoL-CI) with the diagnosis-based Charlson, Elixhauser, and combined comorbidity scores and the prescription-based chronic disease score (CDS) in predicting HRQoL in Agency of Healthcare Research and Quality priority conditions (asthma, breast cancer, diabetes, and heart failure).

Methods:
The Medical Expenditure Panel Survey (2005 and 2007–2011) data was used for this retrospective study. Four disease-specific cohorts were developed that included adult patients (age 18 y and above) with the particular disease condition. The outcome HRQoL [physical component score (PCS) and mental component score (MCS)] was measured using the Short Form Health Survey, Version 2 (SF-12v2). Multiple linear regression analyses were conducted with the PCS and MCS as dependent variables. Comorbidity scores were compared using adjusted R
2.

Results:
Of 140,046 adult participants, the study cohort included 7436 asthma (5.3%), 1054 breast cancer (0.8%), 13,829 diabetes (9.9%), and 937 heart failure (0.7%) patients. Among individual scores, HRQoL-CI was best at predicting PCS and MCS. Adding prescription-based comorbidity scores to HRQoL-CI in the same model improved prediction of PCS and MCS. HRQoL-CI+CDS performed the best in predicting PCS (adjusted R
2): asthma (43.7%), breast cancer (31.7%), diabetes (32.7%), and heart failure (20.0%). HRQoL-CI+CDS and Elixhauser+CDS had superior and comparable performance in predicting MCS (adjusted R
2): asthma (HRQoL-CI+CDS=20.1%; Elixhauser+CDS=19.6%), breast cancer (HRQoL-CI+CDS=12.9%; Elixhauser+CDS=14.1%), diabetes (HRQoL-CI+CDS=17.7%; Elixhauser+CDS=17.7%), and heart failure (HRQoL-CI+CDS=18.1%; Elixhauser+CDS=17.7%).

Conclusions:
HRQoL-CI performed best in predicting HRQoL. Combining prescription-based scores to diagnosis-based scores improved the prediction of HRQoL.
Food Intake Adequacy in Children and Adolescents With Inflammatory Bowel Disease
Authors: Hartman Corina , Marderfeld Luba , Davidson Keren , Mozer‐Glassberg Yael , Poraz Irit , Silbermintz Ari , Zevit Noam , Shamir Raanan 
Published: February 2016

ABSTRACTObjectives:Diet assessment is essential in the care of patients with inflammatory bowel disease (IBD). We aimed to study food intake in children with IBD and evaluated the relation of dietary intake with disease activity and nutritional status in these children.Methods:This cross‐sectional study investigated 68 children and adolescents with IBD (57 Crohn disease, 11 ulcerative colitis). Evaluation included clinical, laboratory, and nutritional assessment including 3 days diet record.Results:Compared with recommended daily allowance, the intake of patients with IBD was significantly poor for carbohydrates (75%, P = 0.016), calcium (49%, P < 0.05), magnesium (76%, P < 0.05), vitamin A (72%, P < 0.05), vitamin E (57%, P < 0.05), and fiber (44%, P < 0.05) and higher for protein (175%, P < 0.05), iron (112%, P < 0.05), and water‐soluble vitamins (118%–189% P < 0.05). Compared with the intakes of healthy children from National Nutritional Survey, the intake of IBD group was lower for calories (78%, P = 0.012), carbohydrates (61% P < 0.05), magnesium (67% P < 0.05), vitamin C (34%, P < 0.05), and fiber (54%, P < 0.05) and high for B12 (141%, P < 0.05). Fifty subjects ate ordinary diets, 7 of 68 children were on exclusive enteral nutrition and 11 of 68 consumed regular food with different polymeric formulas supplements. Compared with children without supplements, children on exclusive enteral nutrition and nutritional supplements (18/68) had significantly better intakes of energy (1870 ± 755 vs 2267 ± 432, P < 0.05), carbohydrates (223 ± 97 vs 292 ± 99, P < 0.05), and all minerals (P < 0.05) and micronutrients (P < 0.05). Dietary intake was not different by disease status (remission or relapse).Conclusions:In the absence of nutritional supplements, food intake is inadequate for many nutrients in many children with IBD.
Interventions for Cognitive Deficits in Breast Cancer Survivors Treated With Chemotherapy
Authors: Vance David E. , Frank Jennifer Sandson , Bail Jennifer , Triebel Kristen L. , Niccolai Lindsay M. , Gerstenecker Adam , Meneses Karen 
Published: February 2016

Background:
Cognitive deficits are distressing adverse effects of chemotherapy that have a negative effect on quality of life in breast cancer survivors (BCSs). Cognitive deficits in cancer survivors are a top research and clinical practice priority.

Objective:
The aims of this study were to describe cognitive deficits that occur after chemotherapy, describe deficits in BCSs treated with chemotherapy within a framework of cognitive reserve and neuroplasticity, and discuss cognitive interventions (ie, cognitive training interventions, compensatory strategies with cognitive training interventions, pharmacological interventions, and complementary and integrative medicine interventions).

Methods:
PubMed search yielded 21 intervention studies of cognitive deficits in BCSs.

Results:
Cognitive training interventions and compensatory strategies with cognitive training resulted in improvement of cognitive deficits. Methylphenidate did not result in cognitive improvement. Modafinil showed improvement in attention. Some complementary and integrative medicine interventions are promising.

Conclusions:
Cognitive training has been most beneficial. Effectiveness of pharmacologic and complementary and integrative medicine interventions has not yet been established.

Implications for Practice:
While limited evidence is available to guide clinical management of cognitive deficits in BCSs, validating patients’ symptom experience and evaluating co-occurring symptom clusters such as fatigue, sleep, and depression, are suggested.
Horizontally transferred gene clusters inE. colimatch size expectations from uber-operons
Authors: Pang Tin Yau , Lercher Martin J. 
Published: February 2016

ABSTRACTAdaptation of bacteria occurs predominantly via horizontal gene transfer. While it is widely recognized that horizontal gene acquisitions frequently encompass multiple genes, it is currently unclear what the size distribution of successfully transferred DNA segments looks like and what evolutionary forces shape this distribution. Here, we identified 7,538 gene pairs that were consistently co-gained on the same branches across a phylogeny of 53E. colistrains. These pairs are significantly enriched in genes that share the same GO annotation. We estimated the genomic distances of these co-gained pairs at the time they were transferred to their host genomes, which shows a sharp upper bound at 30kb. This upper bound is significantly lower than the size limit on gene co-transfers imposed by the carrying capacity of the transfer agents. The observed distance distribution also appears inconsistent with a model based on the co-transfer of genes within operons; instead, we found that the distance distribution of co-transferred genes closely matches the distribution expected from the transfer of uber-operons, i.e., genomic clusters of co-functioning genes beyond operons.
Using media to promote artisan food and beverages: insights from the television industry
Authors: Phillipov Michelle 
Published: February 2016

Purpose
– The increasing frequency with which food and beverage producers feature in mainstream media, including television cooking shows, provide opportunities and pitfalls for using media to promote artisan food and beverage businesses. The purpose of this paper is to evaluate these, as experienced by a group of food and beverage producers who appeared on the popular Australian television show, Gourmet Farmer.

Design/methodology/approach
– Findings are based on semi-structured interviews with 14 of the producers featured on the show, plus textual analysis of relevant segments of the show.

Findings
– While all of the producers felt that food television offered a good promotional tool, those who were most familiar with the practices of media production and whose businesses offered experiences through which viewers could access (or imagine) a “taste” of the Gourmet Farmer life tended to be more satisfied than those who were less familiar with the practices of media production and who expected a greater focus on their products and production practices.

Practical implications
– The development of media skills is essential for artisan producers to get the best outcomes when using media to promote their businesses.

Originality/value
– The experiences of food and beverage producers using food television to promote their businesses have not previously been the subject of thoroughgoing research. This paper offers new insights into how artisan producers can best capitalize on the opportunities offered by food media.
Food private label brands: the role of consumer trust on loyalty and purchase intention
Authors: Calvo Porral Cristina , Levy-Mangin Jean-Pierre 
Published: February 2016

Purpose
– Private label brands of food products are an important component of many consumers’ purchases, as well as an integral element of the retail industry. The purpose of this paper is to examine the moderating role of trust on food private label brands’ purchase intention and loyalty.

Design/methodology/approach
– For this purpose, the authors propose and empirically test a conceptual model comprising variables such as price, familiarity and store image. A sample of 445 respondents was gathered, and the hypotheses were tested performing structural equation modelling.

Findings
– The findings highlight the moderating influence of trust on consumers’ loyalty to food private label brands. In addition, the results obtained reveal the substantially great influence of private label brand familiarity on purchase intention and loyalty. So, it seems that consumer trust and loyalty are strongly associated regarding food private label brands.

Research limitations/implications
– The authors suggest that trust of food private label brands allows retailers to increase consumer loyalty.

Practical implications
– Consequently retail managers should consider the enhancement of trust in the context of a marketing strategy formulation for food private label brands.

Originality/value
– The present study provides insights into the moderating effect of trust on loyalty to food private label brands, as well as evidence of the strong influence of familiarity on private label brands’ proneness, related to food products.
Intentions to purchase food through the internet: developing and testing a model
Authors: Quevedo-Silva Filipe , Freire Otavio , Lima-Filho Dario de Oliveira , Brandão Marcelo Moll , Isabella Giuliana , Moreira Luísa Brito 
Published: February 2016

Purpose
– The purpose of this paper is to assess the factors affecting intentions to purchase food through the internet. Based on the available literature – more specifically, on Ajzen’s (1985) theory of planned behaviour and Grunert and Ramus’ model (2004) – this study proposes and tests a model of planned food purchases via the internet.

Design/methodology/approach
– A quantitative study was conducted among 403 respondents. Data were analyzed using structural equation modelling.

Findings
– The main results demonstrated that attitude and perceived difficulty are the antecedents of purchase intentions. Perceived risk had a negative relationship with attitude. With respect to lifestyle, novelty was positively related to attitude, and freshness was negatively related. In addition, novelty had only an indirect effect on intention, which was mediated by attitude. A wired lifestyle had a positive relationship with attitude, and a negative relationship with perceived difficulty.

Originality/value
– This study operationalizes and improves Grunert and Ramus’ (2004) model of intention to buy food over the internet, by developing, testing and presenting a more comprehensive model.
Identifying determinants to predict intention to complete a health risk assessment
Authors: Ettinger Locke , Adams Ted , Joy Liz , Flint Terri 
Published: February 2016

Purpose
– The purpose of this paper is to determine which constructs (factors) will significantly predict and influence the intention to complete a health risk assessment (HRA) in a hospital employee population.

Design/methodology/approach
– The authors used a cross-sectional design using the theory of planned behavior to design a questionnaire to determine the variables associated with intention to complete an HRA. From a sample of those who completed (n=17) and those who did not complete (n=16) the HRA, the authors used elicitation inquiry to determine the leading factors associated with the intention to complete an HRA. The authors used the responses from this inquiry to develop a questionnaire for a hospital population (n=1,550). A total of 503 hospital employees completed and returned this questionnaire. Using the returned questionnaire data, the authors used logistic regression analysis to determine the best fit model for predicting intention to complete an HRA.

Findings
– The predictive model was statistically significant at the p
<
0.001 level. Discriminant analysis correctly verified the predictive model classified intenders and non-intenders the majority (84 percent) of the time. These study results indicated that perceived behavioral control factors such as having time to complete the HRA, confidence in completing the HRA and trust that the information divulged in the HRA would be kept confidential had the strongest influence (OR=5.39) in predicting participation in taking an HRA.

Research limitations/implications
– Potential limitations of this study include; response and selection bias, homogeneity for age and sex and generalizability. These results help to identify key behavioral-related factors predicting hospital employee participation to complete an HRA.

Practical implications
– Administrators of worksite health promotion programs can systematically explore means of addressing identified participation barriers for the purpose of increasing overall HRA participation success beyond financial incentives.

Originality/value
– The HRA has become a widely accepted assessment tool used to help mitigate the rise in chronic disease. However, HRA completion rates are reported to be low to moderate with very limited research focussed on factors predicting HRA participation.
The promise of tailoring incentives for healthy behaviors
Authors: Kullgren Jeffrey T. , Williams Geoffrey C , Resnicow Kenneth , An Lawrence C , Rothberg Amy , Volpp Kevin G , Heisler Michele 
Published: February 2016

Purpose
– The purpose of this paper is to describe how tailoring financial incentives for healthy behaviors to employees’ goals, values, and aspirations might improve the efficacy of incentives.

Design/methodology/approach
– The authors integrate insights from self-determination theory (SDT) with principles from behavioral economics in the design of financial incentives by linking how incentives could help meet an employee’s life goals, values, or aspirations.

Findings
– Tailored financial incentives could be more effective than standard incentives in promoting autonomous motivation necessary to initiate healthy behaviors and sustain them after incentives are removed.

Research limitations/implications
– Previous efforts to improve the design of financial incentives have tested different incentive designs that vary the size, schedule, timing, and target of incentives. The strategy for tailoring incentives builds on strong evidence that difficult behavior changes are more successful when integrated with important life goals and values. The authors outline necessary research to examine the effectiveness of this approach among at-risk employees.

Practical implications
– Instead of offering simple financial rewards for engaging in healthy behaviors, existing programs could leverage incentives to promote employees’ autonomous motivation for sustained health improvements.

Social implications
– Effective application of these concepts could lead to programs more effective at improving health, potentially at lower cost.

Originality/value
– The approach for the first time integrates key insights from SDT, behavioral economics, and tailoring to turn an extrinsic reward for behavior change into an internalized, self-sustaining motivator for long-term engagement in risk-reducing behaviors.
Information Literacy in participatory environments
Authors: Spiranec Sonja , Banek Zorica Mihaela , Kos Denis 
Published: February 2016

Purpose
– The purpose of this paper is to make a contribution to the theoretical and pragmatic positioning of critical information literacy by interpreting it in the light of epistemological shifts brought about by Web 2.0. Epistemological shifts are elaborated from educational and institutional perspectives as well as from that of scientific research.

Design/methodology/approach
– This paper brings a theoretical analysis drawing on relevant literature for the purpose of identifying the grounds for the mapping of concepts associated with critical information literacy and participatory information environments. Based on descriptive analysis, the paper clarifies distinctions between/participatory/and /information bank/environments and identifies correlations existing between CIL and participatory information environments.

Findings
– There are conceptual disagreements between IL as it was defined and perceived by Zurkowski and how it has to be perceived in the context of contemporary participatory information environments. Current environments are congruent with the core principles and values of critical information literacy and call for the reshaping of IL by introducing into it critical and transformative elements. Not technological aspects of Web 2.0 are crucial in this regard, but epistemological shifts.

Practical implications
– Owing to the fact that Web 2.0 and critical information literacy share many similar features, information environments based on participatory technologies and services provide a context ideally suited for the application of the principles of CIL.

Social implications
– The paper highlights the correlating dimensions between Web 2.0 and critical information literacy and proposes that Web 2.0 makes necessary a more critical outlook on information literacy.

Originality/value
– The paper highlights the correlating dimensions between Web 2.0 and critical information literacy, indicates specific differences between information literacy and critical information literacy and closes with the conclusion that Web 2.0 makes necessary a more critical outlook on information literacy.
Implementation of the overall equipment cost loss (OECL) methodology for comparison with overall equipment effectiveness (OEE)
Authors: Wudhikarn Ratapol 
Published: February 2016

Purpose
– The purpose of this paper is to describe the overall equipment cost loss (OECL) methodology and an implementation of this methodology, to compare the outcomes of OECL with those of overall equipment effectiveness (OEE), and finally to identify the benefits offered by this new methodology.

Design/methodology/approach
– The proposed methodology, OECL, combines six large loss models and a financial model in the performance evaluation of equipment. The six large losses are converted into monetary units. OECL is a new way of evaluating equipment performance that differs from the original OEE methodology and overcomes some of the limitations of OEE. This new methodology can be used to rank problematic machines by accounting for production elements together with finance elements.

Findings
– The OECL and OEE methodologies rank problematic machines differently.

Research limitations/implications
– Efforts were made in this research to identify factors affecting OECL outcomes, but it was found that it was not possible to apply OECL to all scenarios.

Practical implications
– The OECL model can be implemented in a real manufacturing company to help decision-makers better determine the magnitudes of equipment problems and rank problematic pieces of equipment appropriately.

Originality/value
– This OECL method is able to overcome some of OEE’s weaknesses. It can properly prioritise problematic machines by considering both cost and losses.