bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significant atmospheric aerosol pollution caused by world food cultivation
Authors: Bauer Susanne E. , Tsigaridis Kostas , Miller Ron 
Published: May 2016

AbstractParticulate matter is a major concern for public health, causing cancer and cardiopulmonary mortality. Therefore, governments in most industrialized countries monitor and set limits for particulate matter. To assist policy makers, it is important to connect the chemical composition and severity of particulate pollution to its sources. Here we show how agricultural practices, livestock production, and the use of nitrogen fertilizers impact near‐surface air quality. In many densely populated areas, aerosols formed from gases that are released by fertilizer application and animal husbandry dominate over the combined contributions from all other anthropogenic pollution. Here we test reduction scenarios of combustion‐based and agricultural emissions that could lower air pollution. For a future scenario, we find opposite trends, decreasing nitrate aerosol formation near the surface while total tropospheric loads increase. This suggests that food production could be increased to match the growing global population without sacrificing air quality if combustion emission is decreased.
Electron jet of asymmetric reconnection
Authors: Khotyaintsev Yu. V. , Graham D. B. , Norgren C. , Eriksson E. , Li W. , Johlander A. , Vaivads A. , André M. , Pritchett P. L. , Retinò A. , Phan T. D. , Ergun R. E. , Goodrich K. , Lindqvist P.‐A. , Marklund G. T. , Le Contel O. , Plaschke F. , Magnes W. , Strangeway R. J. , Russell C. T. , Vaith H. , Argall M. R. , Kletzing C. A. , Nakamura R. , Torbert R. B. , Paterson W. R. , Gershman D. J. , Dorelli J. C. , Avanov L. A. , Lavraud B. , Saito Y. , Giles B. L. , Pollock C. J. , Turner D. L. , Blake J. D. , Fennell J. F. , Jaynes A. , Mauk B. H. , Burch J. L. 
Published: May 2016

AbstractWe present Magnetospheric Multiscale observations of an electron‐scale current sheet and electron outflow jet for asymmetric reconnection with guide field at the subsolar magnetopause. The electron jet observed within the reconnection region has an electron Mach number of 0.35 and is associated with electron agyrotropy. The jet is unstable to an electrostatic instability which generates intense waves with E∥ amplitudes reaching up to 300 mV m−1 and potentials up to 20% of the electron thermal energy. We see evidence of interaction between the waves and the electron beam, leading to quick thermalization of the beam and stabilization of the instability. The wave phase speed is comparable to the ion thermal speed, suggesting that the instability is of Buneman type, and therefore introduces electron‐ion drag and leads to braking of the electron flow. Our observations demonstrate that electrostatic turbulence plays an important role in the electron‐scale physics of asymmetric reconnection.
Thermoelasticity of Fe3+‐ and Al‐bearing bridgmanite: Effects of iron spin crossover
Authors: Shukla Gaurav , Cococcioni Matteo , Wentzcovitch Renata M. 
Published: May 2016

AbstractWe report ab initio (LDA + Usc) calculations of thermoelastic properties of ferric iron (Fe3+)‐ and aluminum (Al)‐bearing bridgmanite (MgSiO3 perovskite), the main Earth forming phase, at relevant pressure and temperature conditions and compositions. Three coupled substitutions, namely, [Al]Mg‐[Al]Si, [Fe3+]Mg‐[Fe3+]Si, and [Fe3+]Mg‐[Al]Si have been investigated. Aggregate elastic moduli and sound velocities are successfully compared with limited experimental data available. In the case of [Fe3+]Mg‐[Fe3+]Si substitution, the high‐spin (S = 5/2) to low‐spin (S = 1/2) crossover in [Fe3+]Si induces a volume collapse and elastic anomalies across the transition region. However, the associated anomalies should disappear in the presence of aluminum in the most favorable substitution, i.e., [Fe3+]Mg‐[Al]Si. Calculated elastic properties along a lower mantle model geotherm suggest that the elastic behavior of bridgmanite with simultaneous substitution of Fe2O3 and Al2O3 in equal proportions or with Al2O3 in excess should be similar to that of (Mg,Fe2+)SiO3 bridgmanite. However, excess of Fe2O3 should produce elastic anomalies in the crossover pressure region.
Dynamics and distribution of Jovian dust ejected from the Galilean satellites
Authors: Liu Xiaodong , Sachse Manuel , Spahn Frank , Schmidt Jürgen 
Published: May 2016

AbstractIn this paper, the dynamical analysis of the Jovian dust originating from the four Galilean moons is presented. High‐accuracy orbital integrations of dust particles are used to determine their dynamical evolution. A variety of forces are taken into account, including the Lorentz force, solar radiation pressure, Poynting‐Robertson drag, solar gravity, the satellites' gravity, plasma drag, and gravitational effects due to nonsphericity of Jupiter. More than 20,000 dust particles from each source moon in the size range from 0.05 μm to 1 cm are simulated over 8000 (Earth) years until each dust grain hits a sink (moons, Jupiter, or escape from the system). Configurations of dust number density in the Jovicentric equatorial inertial frame are calculated and shown. In a Jovicentric frame rotating with the Sun the dust distributions are found to be asymmetric. For certain small particle sizes, the dust population is displaced towards the Sun, while for certain larger sizes, the dust population is displaced away from the Sun. The average lifetime as a function of particle size for ejecta from each source moon is derived, and two sharp jumps in the average lifetime are analyzed. Transport of dust between the Galilean moons and to Jupiter is investigated. Most of the orbits for dust particles from Galilean moons are prograde, while, surprisingly, a small fraction of orbits are found to become retrograde mainly due to solar radiation pressure and Lorentz force. The distribution of orbital elements is also analyzed.
Optically Active Liquid Crystalline Polyoxometalates via Electrostatic Encapsulation with Cholesterol‐Containing Amphiphile
Authors: Zhang Jing , Li Jingfang , Yuan Hong , Zhang Guohua , Li Bao , Li Wen , Wei Xuehong , Duan Xin‐E , Wu Lixin 
Published: May 2016

AbstractA novel cholesterol‐containing amphiphile was designed and prepared in the study, which is a room‐temperature ionic liquid crystal over a broad temperature range with pronounced chiroptical properties. Four types of inorganic polyoxometalates (PMs) with different numbers of charges were encapsulated by the chiral amphiphile. The incorporation of chiral organic cations triggers achiral PMs in the complexes to show induced chirality through intermolecular interactions, as demonstrated by circular dichroism spectroscopy. The electrostatic encapsulation with mesomorphic promoters provides the inorganic PMs with liquid crystalline behavior, characterized by differential scanning calorimetry, polarized optical microscopy, and X‐ray diffraction. The strategy applied herein represents a unique example of liquid crystalline PM complexes with optical activity.
ChemInform Abstract: Ternary Variants of the Pyrite‐Type: Synthesis and Structure of SrPt4P6, SrPt4As6, BaPt4As6 and BaPt2P3.
Authors: WENSKI G. , MEWIS A. 
Published: May 2016

AbstractThe four title compounds have been prepared by annealing mixtures of the elements (excess Sr and Ba, resp., 1000 °C, 2 weeks).
ChemInform Abstract: pH‐Sensitive Ni(OH)2‐Based Microelectrochemical Transistors.
Authors: NATAN M. J. , BELANGER D. , CARPENTER M. K. , WRIGHTON M. S. 
Published: May 2016

AbstractThe electrochemical properties of pH‐sensitive Ni(OH)2‐based microelectrochemical transistors, prepared by cathodic electrochemical deposition of Ni(OH)2 onto Au or Pt microelectrode arrays, have been investigated.
ChemInform Abstract: Corrosion Behaviour of Type 430 Stainless Steel in Formic and Acetic Acids
Authors: SEKINE I. , HATAKEYAMA S. , NAKAZAWA Y. 
Published: May 2016

Abstracthas been investigated by measuring the corrosion weight loss, the corrosion potential variation with time, the impedance at the steel‐solution interface, and the polarization curve.
ChemInform Abstract: High Temperature Synthesis of Mixed NiWS Hydrotreating Catalysts. Physicochemical Characterization and Catalytic Activities.
Authors: BELLALOUI A. , BREYSSE M. , LACROIX M. , MOSONI L. , ROUBIN M. , VRINAT M. 
Published: May 2016

AbstractNiWS catalysts have been prepared by combination of the elements at 973 K (24 h) and their activities for the hydrogenation of biphenyl have been determined.
ChemInform Abstract: A New Iron(IV) Oxide with High Spin Configuration, SrLaMg0.50Fe0.50O4.
Authors: LI‐MING Z. , DEMAZEAU G. , FOURNES L. , POUCHARD M. , HAGENMULLER P. 
Published: May 2016

AbstractThe title compound has been prepared by calcination (600 °C, 1 h) of a stoichiometric mixture of the corresponding nitrates followed by O2‐treatment (1.
ChemInform Abstract: Electronic and Conformational Effects on π‐Facial Stereoselectivity in Nucleophilic Additions to Carbonyl Compounds.
Authors: WU Y.‐D. , HOUK K. N. 
Published: May 2016

AbstractStructures of the transition states and calculations of the stereoselectivities for the reduction of carbonyl compounds such as (I)‐(III) by NaH or LiAlH4, as well as for the methyl Grignard addition to (III).
ChemInform Abstract: Addition of Arenesulfonyl Iodides to Substituted Phenylacetylenes.
Authors: DA SILVA CORREA C. M. M. , FLEMING M. D. C. M. 
Published: May 2016

AbstractThe addition of arenesulfonyl iodides (I), especially tosyl iodide (Ia), to phenylacetylenes (II) and styrenes (V) in MeOH, EtOH, or benzene is studied.
ChemInform Abstract: Photolysis of 1‐Aryl‐1,2,3‐triazoles; Rearrangement via 1H‐Azirines.
Authors: MITCHELL G. , REES C. W. 
Published: May 2016

AbstractThe preparation of various naphthyltriazoles such as (I), (III), (VII) or (IX) is described.
ChemInform Abstract: (E)‐Selective Olefination of Aldehydes by Means of gem‐Dichromium Reagents Derived by Reduction of gem‐Diiodoalkanes with Chromium(II) Chloride.
Authors: OKAZOE T. , TAKAI K. , UTIMOTO K. 
Published: May 2016

AbstractThe reaction of geminal dichromium reagents, formed from (II) or (V) and CrCl2 or CrCl2/DMF, with aldehydes (I) or (IV) predominantly yields E‐olefinated products (III) or (VI), and thus represents an alternative to the Wittig reaction.
ChemInform Abstract: Study of the Acetyldemetalation of Benzyltrimethylstannane in the Presence of Aluminum Bromide.
Authors: ROZENBERG V. I. , NIKANOROV V. A. , REUTOV O. A. 
Published: May 2016

AbstractAnalogously to the known reaction of benzylmercury chloride, the title reaction gives a mixture of the ketones (III) ‐ (V), together with toluene (VI).
ChemInform Abstract: Asymmetric Syntheses via Heterocyclic Intermediates. Part 32. Asymmetric Synthesis of Cyclic α‐Amino Acids by the Bislactim Ether Method.
Authors: SCHOELLKOPF U. + , HINRICHS R. , LONSKY R. 
Published: May 2016

AbstractThe bislactim ether (I) reacts with the dibromides (II) to give the bromides (III), which are cyclized to the bicyclic compounds (IV).
ChemInform Abstract: Vinylic Organoboranes. Part 2. Improved Procedures for the Protonolysis of Alkenyldialkylboranes Providing a Simplified Stereospecific Synthesis of (Z)‐Alkenes.
Authors: BROWN H. C. , MOLANDER G. A. 
Published: May 2016

AbstractThe alkenylboranes (III), prepared from the alkynes (I) and the boranes (II), undergo mild protonolysis in methanol to yield the cis‐olefins (IV) and the borinates (V).
ChemInform Abstract: Anodic Oxidation of Some Bromophenols: Synthesis of Highly Brominated Diphenyl Ethers and Related Compounds.
Authors: IGUCHI M. , NISHIYAMA A. , ETOH H. , OKAMOTO K. , YAMAMURA S. , KATO Y. 
Published: May 2016

AbstractAnodic oxidation of the bromophenols (I) and (IV) produces the brominated cyclohexadienone phenol ethers (II) and (VI) which are reduced with zinc in acetic acid, yielding the corresponding diphenyl ethers (VIII) and (IX).
ChemInform Abstract: Synthesis of Triphenylene 1,2‐Oxide (1,2‐Epoxy‐1,2‐dihydrophenylene) and Absolute Configuration of the trans‐1,2‐Dihydro Diol Metabolite of Triphenylene. Crystal Structure of (‐)‐(1R,2R)‐trans‐2‐Bromo‐1‐menthyloxyacetoxy‐1,2,3,4‐tetrahydrotriphenylene.
Authors: BOYD D. R. , KENNEDY D. A. , MALONE J. F. , O'KANE G. A. , THAKKER D. T. , YAGI H. , JERINA D. M. 
Published: May 2016

AbstractThe (+)‐configurated as well as the racemic bromohydrin (I) is converted to triphenylene 1,2‐oxide (IV) (the yields refer to the products derived from racemic (I)); in both cases a racemic mixture is obtained in accord with PMO calculations which predict rapid racemization via the corresponding oxepin.
ChemInform Abstract: Synthesis of Tetrahydrofurans from Active Methylene Compounds via Radical Cyclization.
Authors: MORIYA O. , URATA Y. , IKEDA Y. , UENO Y. , ENDO T. 
Published: May 2016

AbstractThe vinyl ethers (III), prepared from the orthoformate (I) and the active methylene compounds (II), are cyclized with tributyltin hydride to yield the tetrahydrofuran derivatives (IV).
ChemInform Abstract: Synthesis of Dichlorocyclobuta(b)benzofuran‐2a‐carboxylic Derivatives and 3‐(Trichloroethenyl)coumarin Through Cross Photocycloadduct of Coumarin and Tetrachloroethylene.
Authors: NONOYAMA S. , YONEZAWA N. , SAIGO K. , HASEGAWA M. , IITAKA Y. 
Published: May 2016

AbstractOn treatment with Et3N, the title photocycloadduct (III) undergoes cycloreversion via the intermediate (IV) to afford the title coumarin derivative (V).
ChemInform Abstract: New Synthesis and Spectroscopic Studies of Thialene (Cyclopenta(b)thiapyran).
Authors: KLEIN R. F. X. , HORAK V. 
Published: May 2016

AbstractThe α‐mercaptoketone (I) is coupled with the chloroketone (II) to give the thioether (III) which undergoes cyclization under acidic conditions, yielding a mixture of (IV) and (V).
ChemInform Abstract: Reactions of Methyl 1‐Oxido‐2‐pyridyl Ketone Oxime with Acetic Anhydride: Formation of a 3‐Methylisoxazolo(4,5‐b)pyridine Derivative.
Authors: TAGAWA Y. , HONJO N. , GOTO Y. , KATO T. 
Published: May 2016

AbstractThe reaction of the isomeric oximes (I) with acetic anhydride (II) is studied.
ChemInform Abstract: Synthesis and Structure‐Activity Relationships of Pyrazolo(4,3‐d)pyrimidin‐7‐ones as Adenosine Receptor Antagonists.
Authors: HAMILTON H. W. , ORTWINE D. F. , WORTH D. F. , BRISTOL J. A. 
Published: May 2016

AbstractNitration of the pyrazoles (I) produces the nitro derivatives (II) which are transformed to the pyrazolo(4,3‐d)pyrimidinones (VII).
ChemInform Abstract: Pyrido(4,3‐e)‐1,2‐thiazine‐3‐carboxamide. Synthesis and Antiinflammatory Activity of Pyrido(4,3‐e)‐1,2‐thiazine‐3‐carboxamide Derivatives.
Authors: SAITO K. , OKUTANI K. 
Published: May 2016

AbstractThe title compounds (V) are synthesized from 3‐sulfoisonicotinic acid (I) by cyclization of the N‐carbamoylmethyl sulfonamides (IV).
ChemInform Abstract: Stereoselective Synthesis of 2‐((Trimethylsilyl)methyl)‐1,3‐butadienes.
Authors: LIU C. , WANG K. K. 
Published: May 2016

AbstractReaction of the allene (I) with 9‐borabicyclononane (9‐BBN) yields the allylborane (II) which reacts with the aldehydes or ketones (III) to give the adducts (IV).
ChemInform Abstract: Derivatives of NPCl2(NSOCl)2 and (NPCl2)2NSOCl. Part 24. Friedel‐Crafts Reaction of (NPCl2)2NSOCl and cis‐NPCl2(NSOCl)2 with a Series of Monosubstituted Benzenes. The Structure of NPCl2NSO‐o‐C6H4ClNSO‐p‐C6H4Cl.
Authors: VIERSEN F. J. , BOSMA E. , DE RUITER B. , DHATHATHREYAN K. S. , VAN DE GRAMPEL J. C. , VAN BOLHUIS F. 
Published: May 2016

AbstractFriedel‐Crafts reaction of (I) with a series of monosubstituted benzenes (II) yields the sulfur substituted products (III).
ChemInform Abstract: Chemistry of Polyfunctional Molecules. Part 94. Chromium‐ and Tungsten‐pentacarbonyl Derivatives of 4‐Methyl‐1,2,6‐triphosphatricyclo(2.2.1.02,6)heptane (P3‐Nortricyclane).
Authors: ELLERMANN J. , DEMUTH A. A. M. 
Published: May 2016

AbstractThe title ligand L is synthesized in a better yield (20%) than earlier described from P4, Na/K alloy and MeC(CH2Br)3 in boiling monoglyme.
ChemInform Abstract: Novel Ni Clusters with Se and PR3 (R: Ph, Et) as Ligands.
Authors: FENSKE D. , OHMER J. 
Published: May 2016

AbstractReactions of Se(SiMe3)2 (II) with the Ni complexes (III), (V), and (VII) lead to the metal‐rich clusters (I), (IV), (VI), and (VIII) as shown in the scheme.
ChemInform Abstract: On the Observance of the “Endo‐Principle” During Diene Synthesis in the δ16‐20‐Keto Steroid Series.
Authors: KAMERNITSKII A. V. , KULIKOVA L. E. , LEVINA I. S. , EL'YANOV B. S. , KAPUL'SKII A. E. , SIMONOV V. I. 
Published: May 2016

Abstract16‐Dehydropregnenolone (I) reacts with piperylene (II) at elevated pressure, producing the 16α,17α‐cyclohexenopregnenolone (III).
ChemInform Abstract: Racemic Origins of the Stereochemically Homogeneous Biosphere. Biased Stereoselectivities in the Formation of Oligomeric Peptides.
Authors: GOLDBERG S. I. , CROSBY J. M. , IUSEM N. D. , YOUNES U. E. 
Published: May 2016

AbstractIsotactic growth of prevital polymers is likely to be an important part of any mechanism that satisfactorily accounts for the enantioselective passage of biomolecules from their racemic beginnings to the stereochemical homogeneity of contemporary life.
ChemInform Abstract: Use of 2‐Methyl‐2‐propanethiol in the Synthesis of C‐Thioglycosyl Derivatives.
Authors: LOPEZ APARICIO F. J. , ZORRILLA BENITEZ F. , SANTOYO GONZALEZ F. , ASENSIO ROSELL J. L. 
Published: May 2016

AbstractReaction of (I) with 2‐methyl‐2‐propanethiol in an acidic medium yields a mixture of the diastereomers (II).
ChemInform Abstract: Vinylic Organoboranes. Part 4. A General, One‐Pot Synthesis of 6‐ and 7‐Alkyn‐1‐ols via Boracyclanes. Influence of Steric Effects in the Iodination of Lithium Alkynyl “Ate” Complexes of Dialkylborinates.
Authors: BROWN H. C. , BASAVAIAH D. , BHAT N. G. 
Published: May 2016

AbstractThe alkynyllithium compounds (II) form "ate" complexes with the boranes (I), (VI), or (VIII).
ChemInform Abstract: New Arsenate Glasses
Authors: VAN UITERT L. G. , GRODKIEWICZ W. H. , BRUCE A. J. 
Published: May 2016

Abstractformed from mixtures of ionic alkali‐metal meta‐arsenates, AAsO3, A: Li, Na, K, Rb, Cs, with somewhat covalent higher valence metal oxides have been prepared.
A multi‐objective performance modelling framework for enabling self‐optimisation of cellular network topology and configurations
Authors: Farooq Hasan , Imran Ali , Abu‐Dayya Adnan 
Published: May 2016

AbstractCellular system optimisation, a cornerstone of cellular systems paradigm, requires new focus shift because of the emergence of plethora of new features shaping the cellular landscape. These features include self‐organising networks with added flavours of heterogeneity of cell sizes and base station types, adaptive antenna radiation patterns, energy efficiency, spatial homogeneity of service levels and focus shift from coverage to capacity. Moreover, to effectively tackle spatiotemporal dynamics of network conditions, a generic low‐complexity framework to quantify the key facets of performance, that is, capacity, quality of service and energy efficiency of the various network topology configurations (NTC), is needed for enabling self‐organising networks empowered cellular system optimisation on the fly. In this paper, we address this problem and present a performance characterisation framework that quantifies the multiple performance aspects of a given heterogeneous NTC through a unified set of metrics that are derived as function of key optimisation parameters and also present a cross comparison of a wide range of potential NTCs. Moreover, we propose a low‐complexity heuristic approach for holistic optimisation of future heterogeneous cellular systems for joint optimality in the multiple desired performance indicators. The performance characterisation framework also provides quantitative insights into the new tradeoffs involved in optimisation of emerging heterogeneous networks and can pave the way for much needed further research in this area. Copyright © 2016 John Wiley & Sons, Ltd.
Higher Gemcitabine Dose Was Associated With Better Outcome of Osteosarcoma Patients Receiving Gemcitabine‐Docetaxel Chemotherapy
Authors: Lee Jun Ah , Jeon Dae‐Geun , Cho Wan Hyeong , Song Won Seok , Yoon Hoi Soo , Park Hyeon Jin , Park Byung Kiu , Choi Hyoung Soo , Ahn Hyo Seop , Lee Ji Won , Yoo Keon Hee , Sung Ki Woong , Koo Hong Hoe , Kang Hyoung Jin , Park Kyung Duk , Shin Hee Young , Koh Kyung‐Nam , Im Ho Joon , Seo Jong Jin , Lim Yeon Jung , Baek Hee Jo , Kook Hoon 
Published: May 2016

ABSTRACTBackgroundEfficacy of gemcitabine and docetaxel (GEM + DOC) chemotherapy in patients with recurrent or refractory osteosarcoma was evaluated.MethodsData of 53 patients from 9 institutions, who received GEM (675 or 900 mg/m2 on days 1 and 8) and DOC (100 mg/m2 on day 8), were retrospectively reviewed.ResultsGEM + DOC was administered as adjuvant (n = 25) or palliative chemotherapy (n = 28). Patients received a median 3 courses (range, 1−10 courses). Objective response rate (CR + PR, where CR is complete response and PR is partial response) and disease control rate (CR+ PR + SD, where SD is stable disease) were 14.3% and 28.6%, respectively. Disease control rate was higher in patients receiving 900 mg/m2 GEM than in patients receiving 675 mg/m2 (50.0% vs. 12.5%, P = 0.03). Higher GEM dose was associated with better survival, both in adjuvant (1‐year overall survival, 90.9 ± 8.7% vs. 38.5 ± 13.5%, P = 0.002) and palliative settings (50.0 ± 14.4% vs. 31.3 ± 11.6%, P = 0.04).ConclusionsFurther studies are necessary to investigate the efficacy of more aggressive and higher doses of GEM + DOC chemotherapy in osteosarcoma.
Pediatric Sarcomas Are Targetable by MR‐Guided High Intensity Focused Ultrasound (MR‐HIFU): Anatomical Distribution and Radiological Characteristics
Authors: Shim Jenny , Staruch Robert M. , Koral Korgun , Xie Xian‐Jin , Chopra Rajiv , Laetsch Theodore W. 
Published: May 2016

BackgroundDespite intensive therapy, children with metastatic and recurrent sarcoma or neuroblastoma have a poor prognosis. Magnetic resonance guided high intensity focused ultrasound (MR‐HIFU) is a noninvasive technique allowing the delivery of targeted ultrasound energy under MR imaging guidance. MR‐HIFU may be used to ablate tumors without ionizing radiation or target chemotherapy using hyperthermia. Here, we evaluated the anatomic locations of tumors to assess the technical feasibility of MR‐HIFU therapy for children with solid tumors.ProcedurePatients with sarcoma or neuroblastoma with available cross‐sectional imaging were studied. Tumors were classified based on the location and surrounding structures within the ultrasound beam path as (i) not targetable, (ii) completely or partially targetable with the currently available MR‐HIFU system, and (iii) potentially targetable if a respiratory motion compensation technique was used.ResultsOf the 121 patients with sarcoma and 61 patients with neuroblastoma, 64% and 25% of primary tumors were targetable at diagnosis, respectively. Less than 20% of metastases at diagnosis or relapse were targetable for both sarcoma and neuroblastoma. Most targetable lesions were located in extremities or in the pelvis. Respiratory motion compensation may increase the percentage of targetable tumors by 4% for sarcomas and 10% for neuroblastoma.ConclusionsMany pediatric sarcomas are localized at diagnosis and are targetable by current MR‐HIFU technology. Some children with neuroblastoma have bony tumors targetable by MR‐HIFU at relapse, but few newly diagnosed children with neuroblastoma have tumors amenable to MR‐HIFU therapy. Clinical trials of MR‐HIFU should focus on patients with anatomically targetable tumors.