bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial analysis of genetic diversity in a comprehensive collection of the native grass Bromus auleticus Trinius (ex Nees) in Uruguay
Authors: Condón F. , Jaurena M. , Reyno R. , Otaño C. , Lattanzi F. A. 
Published: January 2017

AbstractBromus auleticus Trinius (ex Nees) is a perennial allogamous C3 grass native to the Campos grasslands. It has potential to play a key role in restoration of both abandoned agricultural and overgrazed lands. We aim to reveal the existence of local adaptation and to assess whether phenotypes could be differentiated in relation to their ecogeographic region of origin. Previous reports estimated significant levels of variability among and within populations, but as yet there is no evidence of local adaptation and phenotypic relations with ecogeographic regions for this species. Indeed, there is a lack of knowledge about the spatial distribution of diversity, which limits the possibilities of using B. auleticus in ecological restoration and plant breeding. A comprehensive collection of 82 accessions of B. auleticus from eight ecogeographic regions within Uruguay was used to characterize diversity by measuring phenologic, morphologic, productive and reproductive traits. We found high diversity among B. auleticus accessions, and the spatial distribution of this diversity follows a pattern accounted by ecogeographic regions to a large extent. Our results also indicate large genotype × environment interaction, confirming local adaptation. Phenotypic values permitted, with a 3.7% error rate, discrimination of accessions according to their ecogeographic region of origin, suggesting the existence of differentiated ecotypes. We consider that the diversity observed should be conserved and used for breeding cultivars of this species and for the restoration of degraded grasslands by considering ecogeographic regions when selecting seed sources.
Clinical features of shiitake dermatitis: a systematic review
Authors: Nguyen Austin H. , Gonzaga Maria I. , Lim Victoria M. , Adler Michael J. , Mitkov Mario V. , Cappel Mark A. 
Published: January 2017

SummaryShiitake dermatitis is a rare cutaneous reaction to lentinan, a polysaccharide component in the cell walls of shiitake mushrooms (Lentinula edodes). Herein, we systematically review the case report and case series English‐language literature on shiitake dermatitis, which refers to a total of 50 patients (38 males, 12 females; mean age: 44.58 years). The majority of cases occurred after the consumption of raw mushrooms, whereas 22% of cases were caused by the eating of lightly or undercooked mushrooms. The most common clinical presentations, localized symptoms, and systemic findings include linear flagellated dermatitis (98%), pruritus (78%), and fever, diarrhea, and mucosal ulcers, respectively. The diagnosis of this entity continues to be based on clinical findings as laboratory abnormalities, and the findings of skin biopsies and patch/prick tests are nonspecific and inconsistent. The condition is self‐limiting, resolving in approximately 12.5 d without treatment. Based on the included case reports, it appears that medical treatment may slightly shorten the course of disease (to 9–11 d, varying by therapy) but should be considered on an individual patient basis. However, the treatment of symptoms, reassurance, and the avoidance of re‐exposure are sufficient treatment recommendations for this condition.
Direct Comparison of Point‐by‐Point and Rapid Ultra‐High‐Resolution Electroanatomical Mapping in Patients Scheduled for Ablation of Atrial Fibrillation
Authors: ROTTNER LAURA , METZNER ANDREAS , OUYANG FEIFAN , HEEGER CHRISTIAN , HAYASHI KENTARO , FINK THOMAS , LEMES CHRISTINE , MATHEW SHIBU , MAURER TILMAN , REIßMANN BRUNO , REXHA ENIDA , RIEDL JOHANNES , SAGUNER ARDAN M. , SANTORO FRANCESCO , KUCK KARL‐HEINZ , SOHNS CHRISTIAN 
Published: January 2017

Point‐by‐Point versus Rapid Ultra‐High‐Resolution Electroanatomical Mapping in AFIntroductionThree‐dimensional electroanatomical mapping (EAM) is an established tool facilitating catheter ablation. In this context, the novel Rhythmia system sets a new bar in fast high‐resolution mapping. The aim of this study was to directly compare point‐by‐point versus rapid ultra‐high‐resolution EAM in patients scheduled for ablation of atrial fibrillation (AF) with focus on procedural data, acute success, and midterm clinical outcome.Methods and ResultsA total number of 74 consecutive patients (48/74 male) with symptomatic AF were scheduled to undergo pulmonary vein isolation (PVI) using either Carto or Rhythmia. The Carto‐guided procedures were performed using point‐by‐point acquisition according to our routine approach, whereas for Rhythmia, fast anatomical mapping was utilized. Comparing Rhythmia‐ versus Carto‐guided ablation approaches, we observed a significantly longer total mapping time (P = 0.001), longer total fluoroscopy time (P = 0.001), more delivered RF‐applications (P = 0.019), and longer total RF‐duration (P = 0.002). There was no difference regarding total ablation time (P = 0.707), total procedure duration (P = 0.99), and acute procedural success. During follow‐up, 84.8% of patients remained free from any AF/AT‐recurrence using Carto versus 88.2% when using Rhythmia (P = 0.53). From Kaplan–Meier analysis, the event rate estimations were 15% versus 13.5%, respectively.ConclusionThe present study reports our first clinical experience using Rhythmia in direct comparison with the established Carto system for AF ablation. Our data clearly demonstrate that Rhythmia was proved to be effective and well applicable but more data will be mandatory before final conclusions can be drawn.
Comparison of hospital outcomes and resource use in acute COPD exacerbation patients managed by teaching versus nonteaching services in a community hospital
Authors: Abusaada Khalid , Alsaleh Leen , Herrera Victor , Du Yuan , Baig Hassan , Everett George 
Published: January 2017

AbstractRationale, aims, and objectivesThe impact of teaching versus nonteaching services on outcomes and resource use in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is unknown. The aim of the study is to evaluate the impact of an internal medicine teaching service compared to a nonteaching service on outcomes and resource use in patients admitted with AECOPD in a community teaching hospital.MethodsA retrospective cohort study of patients admitted for a primary diagnosis of chronic obstructive pulmonary disease exacerbation to Florida Hospital Orlando, a large community teaching hospital, between January 1, 2011, and December 31, 2014. Data were extracted from Premier administrative database. Risk adjusted length of stay (LOS), cost of hospitalization, 30‐day readmissions, and mortality rate were measured. Risk adjustment for outcomes was based on Premier CareScience methodology.ResultsA total of 1419 patients were included, 306 in the teaching group and 1113 in the nonteaching group. Risk adjusted cost and LOS were significantly lower in the teaching group compared to the nonteaching group (observed/expected cost 0.66 vs 1.06, P < .001) and (observed/expected LOS 0.93 vs 1.69, P < .001), respectively. No significant difference was found between the 2 groups in risk adjusted mortality and readmissions (P = .48 and .89, respectively). Use of consults was significantly lower in the teaching groups with 73% vs 31% of the patient in the teaching group had no consults compared to the nonteaching group (P < .001). The teaching service was significantly associated with decreased use of consults after adjustment for other variables (odds ratio, 0.17, 95% CI, 0.15‐0.23, P < .001).ConclusionThe teaching service had more favorable outcomes compared to nonteaching services in patients hospitalized for AECOPD. The physician practice model has a major impact on the cost, LOS, and use of consults in patients with AECOPD.
Petrology, phase equilibria modelling and zircon U–Pb geochronology of Paleoproterozoic mafic granulites from the Fuping Complex, North China Craton
Authors: Tang L. , Santosh M. , Tsunogae T. , Koizumi T. , Hu X.‐K. , Teng X.‐M. 
Published: January 2017

AbstractThe Fuping Complex is one of the important basement terranes within the central segment of the Trans‐North China Orogen (TNCO) where mafic granulites are exposed as boudins within tonalite–trondhjemite–granodiorite (TTG) gneisses. Garnet in these granulites shows compositional zoning with homogeneous cores formed in the peak metamorphic stage, surrounded by thin rims with an increase in almandine and decrease in grossular contents suggesting retrograde decompression and cooling. Petrological and phase equilibria studies including pseudosection calculation using thermocalc define a clockwise P–T path. The peak mineral assemblages comprise garnet+clinopyroxene+amphibole+quartz+plagioclase+K‐feldspar+ilmenite±orthopyroxene±magnetite, with metamorphic P–T conditions estimated at 8.2–9.2 kbar, 870–882 °C (15FP‐02), 9.6–11.3 kbar, 855–870 °C (15FP‐03) and 9.7–10.5 kbar, 880–900 °C (15FP‐06) respectively. The pseudosections for the subsequent retrograde stages based on relatively higher H2O contents from P/T–M(H2O) diagrams define the retrograde P–T conditions of <6.1 kbar, <795 °C (15FP‐02), 5.6–5.8 kbar, <795 °C (15FP‐03), and <9 kbar, <865 °C (15FP‐06) respectively. Data from LA‐ICP‐MS zircon U–Pb dating show that the mafic dyke protoliths of the granulite were emplaced at c. 2327 Ma. The metamorphic zircon shows two groups of ages at 1.96–1.90 Ga (peak at 1.93–1.92 Ga) and 1.89–1.80 Ga (peak at 1.86–1.83 Ga), consistent with the two metamorphic events widely reported from different segments of the TNCO. The 1.93–1.92 Ga ages are considered to date the peak granulite facies metamorphism, whereas the 1.86–1.83 Ga ages are correlated with the retrograde event. Thus, the collisional assembly of the major crustal blocks in the North China Craton (NCC) might have occurred during 1.93–1.90 Ga, marking the final cratonization of the NCC.
Classification of starch gel texture for the elderly diets based on instrumental and sensory methodology
Authors: Kim Yonggi , Kim Hyeon Ji , Cho Wanil , Ko Sanghoon , Park Sung Kwon , Lee Suyong 
Published: January 2017

AbstractAn experimental attempt was made to bridge the gap between instrumental and sensory texture for the elderly diets in a corn starch gel system. Uniaxial compression was applied to measure the instrumental hardness of corn starch gels that was correlated with their sensory properties perceived by the elderly aged 60 and older. Instrumental and sensory hardness values of the starch gel samples were found to have good polynomial and linear correlations (R2 =.99) with the level of corn starch, respectively. A fairly linear relationship (R2 =.96) was observed between the instrumental and sensory hardness in terms of the logarithm of stress. In principal component analysis, two principal components that accounted for 86.71% of the total variability, separated the gel texture in terms of hardness/springiness and moistness, respectively. The categories of the starch gel samples were subdivided into five groups with different stress ranges. This classification suggested in this study appeared to provide useful information for modifying the texture of solid foods for the elderly diets.Practical applicationsAs the elderly population is increasing throughout the world, there are growing interests in developing food products for older adults with difficulties in chewing and swallowing in the food industry. In this study, the instrumental texture of solid foods in a starch gel system was correlated with the sensory properties perceived by the people aged 60 and older. Based on the principal component analysis, the corn starch gel samples with different hardness were classified into the five groups that were presented with the ranges of stress values. The results obtained in this study may thus provide valuable information on the standard criteria and guidelines customized for the elderly.
Split Ponds Effectively Overwinter Golden Shiners
Authors: Smith Matthew A. , Stone Nathan M. 
Published: January 2017

AbstractBaitfish producers have expressed interest in adopting the split‐pond production system. However, confining fish to 20% of the pond area in split‐pond systems effectively quintuples fish density within the culture unit as compared with densities in open ponds. Winter conditions are known to be relatively more stressful on smaller fish, and high densities within split‐pond culture units could increase losses. A 139‐d study was conducted during the winter to compare the production of golden shiners, Notemigonus crysoleucas, in traditional earthen ponds and split ponds at two densities. Golden shiners were stocked at 646 kg/ha or 1292 kg/ha (ca. 370,500 or 741,000 fish/ha, respectively) into 12, 0.04‐ha, netted earthen ponds (six split ponds and six traditional). Feeding rate, nightly aeration hours, and daily circulation hours were reduced when water temperature decreased. At harvest, net yields were significantly lower in the split ponds as compared with traditional ponds at each density (53 and 113 kg/ha less in the low‐ and high‐density split‐pond treatments, respectively). Estimated survival was high (>87%) and did not differ among treatments. Results showed that, although net yield was reduced, small baitfish could be successfully overwintered in split‐pond culture units in preparation for the spring crappie market.
Novel Rosaceae plant elicitor peptides as sustainable tools to control Xanthomonas arboricola pv. pruni in Prunus spp.
Authors: Ruiz Cristina , Nadal Anna , Montesinos Emilio , Pla Maria 
Published: January 2017

SummaryFruit crops are regarded as important health promoters and constitute a major part of global agricultural production, and Rosaceae species are of high economic impact. Their culture is threatened by bacterial diseases, whose control is based on preventative treatments using compounds of limited efficacy and negative environmental impact. One of the most economically relevant examples is the pathogen Xanthomonas arboricola pv. pruni (Xap) affecting Prunus spp. The plant immune response against pathogens can be triggered and amplified by plant elicitor peptides (Peps), perceived by specific receptors (PEPRs). Although they have been described in various angiosperms, scarce information is available on Rosaceae species. Here, we identified the Pep precursor (PROPEP), Pep and PEPR orthologues of 10 Rosaceae species and confirmed the presence of the Pep/PEPR system in this family. We showed the perception and elicitor activity of Rosaceae Peps using the Prunus–Xap pathosystem as proof‐of‐concept. Treatment with nanomolar doses of Peps induced the corresponding PROPEP and a set of defence‐related genes in Prunus leaves, and enhanced resistance against Xap. Peps from the same species had the highest efficiencies. Rosaceae Peps could potentially be used to develop natural, targeted and environmentally friendly strategies to enhance the resistance of Prunus species against biotic attackers.
The complex patient: A concept clarification
Authors: Manning Eli , Gagnon Marilou 
Published: January 2017

AbstractOver the last decade, the concept of the “complex patient” has not only been more widely used in multidisciplinary healthcare teams and across various healthcare disciplines, but it has also become more vacuous in meaning. The uptake of the concept of the “complex patient” spans across disciplines, such as medicine, nursing, and social work, with no consistent definition. We review the chronological evolution of this concept and its surrogate terms, namely “comorbidity,” “multimorbidity,” “polypathology,” “dual diagnosis,” and “multiple chronic conditions.” Drawing on key principles of concept clarification, we highlight disciplinary usage in the literature published between 2005 and 2015 in health sciences, attending to overlaps and revealing nuances of the complex patient concept. Finally, we discuss the implications of this concept for practice, research, and theory.
“Sufficient health” as perceived by Thai villagers: A qualitative study
Authors: Arpanantikul Manee , Phuphaibul Rutja , Khuwatsumrit Kusuma 
Published: January 2017

AbstractGlobalization has led to the rapid modernization of Thai villagers' traditional lifestyle, with significant consequential changes in health. The integration of the sufficiency economy philosophy with health – a concept known as “sufficient health” – can improve health and wellbeing; however, little is known of the actual meaning of “sufficient health.” This qualitative study explored the meaning of sufficient health as perceived by Thai villagers. Data were collected from 122 villagers living in a rural Thai community and analyzed using content analysis. The findings revealed five themes reflecting the meaning of sufficient health: being healthy and not having an illness, having regular health check‐ups, performing self‐care, living sufficiently, and avoiding risks. Understanding the meaning attributed to sufficient health can help nurses provide appropriate health care for villagers while retaining concern and respect for their cultural backgrounds. Importantly, providing opportunities to villagers to participate in health activities could help them recognize and sustain sufficient health.
Patients’ and Physicians’ Perceptions Regarding the Benefits of Atrial Fibrillation Ablation
Authors: BADIN AUROA , PARR ALAN R. , BANGA SANDEEP , WIGANT REBECCA R. , BAMAN TIMIR S. 
Published: January 2017

BackgroundIt is unclear whether patients and physicians understand that atrial fibrillation ablation (AFA) has been shown to only improve symptomology and not reduce morbidity or mortality.MethodsNote that 177 of 445 (40%) consecutive patients referred to an electrophysiology clinic for atrial fibrillation (AF) management responded anonymously to our survey via mail. Note that 105 of 656 (15%) physicians responded to our survey via email. Comparisons among groups were conducted using χ2 test for categorical variables. Odds ratios and 95% confidence intervals were estimated by using a multivariate logistic regression model.ResultsAlmost half of patients and physicians believed AF ablation (AFA) would eliminate the need for anticoagulation (43% vs. 44%, P > 0.05) while the majority of both groups believed AFA would improve survival (58% vs. 67%, P = 0.308). The great majority of both groups believed AFA would decrease stroke rates (89% vs. 80%, P = 0.106). When comparing noncardiologists (n = 86) to cardiologists (n = 19), noncardiologists were more likely to believe that an AFA would eliminate the need for anticoagulation 49% vs. 21% (X = 4.9, P = 0.04), improve survival 80% vs. 11% (X = 30.2, P < 0.001), and decrease stroke 87% vs. 44% (X = 15.6, P < 0.001), respectively.ConclusionsThe perceived benefit of AFA by patients and physicians is not supported by the medical literature. It is the responsibility of the electrophysiology community to educate patients and referring physicians regarding the true benefits of AFA. In addition, our study displays the great need for long‐term clinical trials examining the impact AFA has on morbidity and mortality.
Genome‐wide association study for 13 agronomic traits reveals distribution of superior alleles in bread wheat from the Yellow and Huai Valley of China
Authors: Sun Congwei , Zhang Fuyan , Yan Xuefang , Zhang Xiangfen , Dong Zhongdong , Cui Dangqun , Chen Feng 
Published: January 2017

SummaryBread wheat is a leading cereal crop worldwide. Limited amount of superior allele loci restricted the progress of molecular improvement in wheat breeding. Here, we revealed new allelic variation distribution for 13 yield‐related traits in series of genome‐wide association studies (GWAS) using the wheat 90K genotyping assay, characterized in 163 bread wheat cultivars. Agronomic traits were investigated in 14 environments at three locations over 3 years. After filtering SNP data sets, GWAS using 20 689 high‐quality SNPs associated 1769 significant loci that explained, on average, ~20% of the phenotypic variation, both detected already reported loci and new promising genomic regions. Of these, repetitive and pleiotropic SNPs on chromosomes 6AS, 6AL, 6BS, 5BL and 7AS were significantly linked to thousand kernel weight, for example BS00021705_51 on 6BS and wsnp_Ex_c32624_41252144 on 6AS, with phenotypic variation explained (PVE) of ~24%, consistently identified in 12 and 13 of the 14 environments, respectively. Kernel length‐related SNPs were mainly identified on chromosomes 7BS, 6AS, 5AL and 5BL. Plant height‐related SNPs on chromosomes 4DS, 6DL, 2DS and 1BL were, respectively, identified in more than 11 environments, with averaged PVE of ~55%. Four SNPs were confirmed to be important genetic loci in two RIL populations. Based on repetivity and PVE, a total of 41 SNP loci possibly played the key role in modulating yield‐related traits of the cultivars surveyed. Distribution of superior alleles at the 41 SNP loci indicated that superior alleles were getting popular with time and modern cultivars had integrated many superior alleles, especially for peduncle length‐ and plant height‐related superior alleles. However, there were still 19 SNP loci showing less than percentages of 50% in modern cultivars, suggesting they should be paid more attention to improve yield‐related traits of cultivars in the Yellow and Huai wheat region. This study could provide useful information for dissection of yield‐related traits and valuable genetic loci for marker‐assisted selection in Chinese wheat breeding programme.
Nutritional status and feeding problems in pediatric attention deficit–hyperactivity disorder
Authors: Sha'ari Norsuhaila , Manaf Zahara Abdul , Ahmad Mahadir , Rahman Fairuz Nazri Abd 
Published: January 2017

AbstractBackgroundChildren with attention deficit–hyperactivity disorder (ADHD) may be at risk of nutrient deficiency due to the inability to sit through meals. This comparative cross‐sectional study was therefore carried out to determine the nutritional status and feeding problems of ADHD children aged 4–12 years.MethodsSociodemographic data, anthropometric measurements and 3 day dietary intake record were collected from 54 ADHD children and 54 typical development (TD) children. The Behavioral Pediatrics Feeding Assessment Scale was used to assess feeding problems.ResultsMean subject age was 8.6 ± 2.1 years. On anthropometric assessment, 11.1% of the ADHD children had wasting, while 1.9% had severe wasting. In contrast, none of the TD children had wasting. Approximately 5.6% of the ADHD children had stunting, as compared with 3.7% of the TD children, while none of the TD children had severe stunting compared with 3.7% of the ADHD children. More than half of the ADHD children had mid‐upper arm circumference (MUAC) below the 5th percentile, indicating undernutrition, compared with only 35.2% of TD children. More than one‐third of the ADHD children had feeding problems compared with 9.3% of TD children. There was a significant negative relationship between the ADHD children's feeding problems and bodyweight (r = −0338, P = 0.012), body mass index (r = −0322, P = 0.017) and MUAC (r = −0384, P = 0.004).ConclusionAlmost half of the ADHD children had suboptimal nutrition compared with 11.1% of the TD children. It is imperative to screen ADHD children for nutritional status and feeding problems to prevent negative health impacts later on.