bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Outcomes of a Cognitive-Behavioral Skills Building Program on the Mental Health and Healthy Behaviors of Prenursing Students
Authors: Hoying Jacqueline , Terry Ayanna , Kelly Stephanie , Gray-Bauer Rosalind , Melnyk Bernadette Mazurek 
Published: October 2024

Background:
Nursing students experience significantly more stress related diseases when compared to non-nursing students, and the state of their mental health can result in short-term increased attrition rates and increased nursing shortages.

Purpose:
A preexperimental pre-post study design was used to examine mental health and healthy behaviors among prenursing students.

Methods:
Cohorts received the MINDSTRONG© program either in-person or virtually. Data analysis included Personal Wellness Assessments completed at both pre- and poststudy for all participants (n = 110).

Results:
Both groups postintervention had statistically significant decreases in anxiety, depression, and stress and statistically significant increases in healthy lifestyle behaviors and beliefs. Students with elevated depression and anxiety scores at baseline had greater decreases postintervention than the overall groups.

Conclusion:
The outcomes for both cohorts were positive and effective in reducing stress, anxiety, and depressive symptoms. Healthy behaviors were improved and align with findings with an in-person format. Findings from this study support implementation of MINDSTRONG in synchronous sessions, either in-person or virtual.
Physical Therapy Dose After Orthopedic Multilevel Surgery Varies by Ambulatory Status in Children With Cerebral Palsy: A Pilot Study
Authors: Greve Kelly , Bailes Amy F. , Zhang Nanhua , Long Jason , Aronow Bruce , Mitelpunkt Alexis 
Published: October 2024

Purpose:
To characterize physical therapy (PT) dose for children with cerebral palsy (CP) after multi-level surgery (MLS) and examine variation by ambulatory status and surgical burden.

Methods:
PT dose (Frequency, Intensity, Time, Type) data were extracted from electronic records of children with CP who received outpatient PT the year after MLS.

Results:
Seventeen children, mean 9 years, female (n=10), ambulatory (n=10), and high surgical burden (n=12) were included. In the year after surgery, 345 visits occurred. Intensity across visits was above average. Time was greatest for pre-functional activities, gait, and transitions/transfers. Types most often delivered were neuromuscular, musculoskeletal, and education/training. Ambulatory children received significantly more visits, higher intensity, and time in pre-functional activities and gait than non-ambulatory children. No differences in type by ambulatory status and PT dose by surgical burden were found.

Conclusion:
PT dose varied the first year after MLS indicating the need for guidelines by ambulatory status.

Video Abstract:
Supplemental Digital Content available at: http://links.lww.com/PPT/A516
Vault RNAs aid viral infection by facilitating nuclear export of hnRNP C and ELAVL1
Authors: Stok Jorn E. , van der Kooij Sander B. , Gravekamp Dennis , ter Haar Laurens R. , de Wolf Jasper W. , Salgado-Benvindo Clarisse , Nelemans Tessa , Grijmans Bart J.M. , Tjokrodirijo Rayman T.N. , de Ru Arnoud H. , van Veelen Peter A. , van Hemert Martijn J. , Kikkert Marjolein , van der Veen Annemarthe G. 
Published: October 2024

AbstractVault RNAs (vtRNAs) are a family of four small non-coding RNAs (ncRNAs) that are ubiquitously expressed in many eukaryotes and that regulate multiple cellular pathways. Their expression is increased upon infection with various DNA and RNA viruses. This suggests they are either co-opted by the virus to aid replication or function as an antiviral restriction factor. However, their precise molecular function remains unclear. Here, we show that replication of picornaviruses, alphaviruses, and beta-coronaviruses broadly enhances vtRNA expression. We find that genetic loss of vtRNAs inhibits replication of Sindbis virus (SINV) and encephalomyocarditis virus (EMCV), independent of the antiviral type I interferon (IFN) response. A proteomic screen uncovered the vtRNA interactome and revealed that vtRNAs associate with RNA binding proteins ELAVL1 and hnRNP C in uninfected and infected cells. VtRNAs facilitate the translocation of ELAVL1 and hnRNP C from the nucleus to the cytoplasm in infected cells, an event that is required for efficient viral replication. Moreover, hnRNP C and ELAVL1 fail to associate with viral RNA in the cytosol of SINV-infected cells in the absence of vtRNAs. Together, our findings reveal a novel molecular mechanism by which vtRNAs exert proviral activity during the course of SINV and EMCV infection, which opens up new avenues for therapeutic targeting to fight infectious diseases.
Isolation and Characterization of a Roseophage Representing a Novel Genus in the N4-like Rhodovirinae Subfamily Distributed in Estuarine Waters
Authors: Huang Xingyu , Yu Chen , Lu Longfei 
Published: October 2024

AbstractBackgroundRoseobacteraceae, often referred to as the marine roseobacter clade (MRC), are pivotal constituents of bacterial communities in coastal and pelagic marine environments. During the past two decades, 75 roseophages that infect variousRoseobacteraceaelineages have been isolated. The N4-likeRhodovirinaesubfamily, which encompasses 15 members, represents the largest clade among these roseophages.ResultsIn this study, we isolated a novel roseophage, vB_DshP-R7L, that infectsDinoroseobacter shibaeDFL12 from Xiamen Bay in the East China Sea. Conserved genes ofSchitoviridaehave been identified in the genome of vB_DshP-R7L, and following phylogenetic analysis suggest that the newly isolated phage is a member of theRhodovirinaesubfamily and is indicative of a newly proposed genus,Xianganvirus. The genome of vB_DshP-R7L harbors six auxiliary metabolic genes (AMGs), most of which potentially enhance DNAde novosynthesis. Additionally, a gene encoding ribosomal protein was identified. Comparative genomic analysis of AMG content amongRhodovirinaeindicates a distinct evolutionary history characterized by independent ancient horizontal gene transfer events. Read-mapping analysis reveals the prevalence of vB_DshP-R7L and otherRhodovirinaeroseophages in estuarine waters.ConclusionsOur work illustrates the genomic features of a novel roseophage clade among N4-likeRhodovirinae. The AMG content of vB_DshP-R7L are under severe purification selection, which revealed their possible ecological importance. We also demonstrated that vB_DshP-R7L and otherRhodovirinaeroseophages are restrictively distributed in estuaries. Our isolation and characterization of this novel phage expand the understanding of the phylogeny, gene transfer history and biogeography of N4-likeRhodovirinaeinfecting marineRoseobacteraceae.
Cell-free immuno-profiling on a genetically programmed biochip
Authors: Dupin Aurore , Vonshak Ohad , Arad Valerie , Levanon Maya , Avidan Noa , Divon Yiftach , Peleg Steve , Thompson Seth , Noireaux Vincent , Daube Shirley S. , Bar-Ziv Roy H. 
Published: October 2024

AbstractEmerging cell-free synthetic biology approaches provide biosafe, cheap, and versatile genetic tools to advance therapeutic research and development. Combined with micro-fabrication technology, we developed a platform to quantitatively reconstitute interactions of cell-free synthesized antigens with antibodies and human receptors in miniaturized compartments on a silicon chip. Photolithographic surface patterning of protein traps and on chip expression from high density gene brushes generated a continuous surface density gradient of fluorescently labeled antigens. Antibodies binding to the antigen gradient generate a full binding curve in each single compartment for affinity determination. We used the SARS-CoV-2 antigens as a model to profile the specificity and affinity of monoclonal antibodies to > 30 viral epitopes synthesized simultaneously on one chip in a genotype-phenotype linked compartments. We further profiled polyclonal antibodies in minute volumes of human sera, revealing patient-specific epitope profiles that are difficult to detect by conventional approaches. Cell-free co-synthesis of the human ACE2 receptor with the viral Receptor-Binding-Domain yielded relative binding affinities to different SARS-CoV-2 variants. This rapid, quantitative, and on-chip genetically programmed approach allows to study complex protein-protein interactions independent of protein purification steps for human immuno-profiling with a fast response time for combating emerging pathogens.
Exploring construction technical intelligence: a grounded theory approach to international construction professionals' adjustment in new technical contexts
Authors: Luo Jungang , Santoso Djoen San , Xu Weitao 
Published: October 2024

PurposeThis study aims to investigate the process of adjustment for international construction professionals when facing new technical contexts. It introduces a framework called construction technical intelligence (CTI) and seeks to provide valuable insights and practical guidance for professionals involved in international construction projects.Design/methodology/approachIn this study, a grounded theory approach was employed, which included conducting in-depth interviews with 28 professionals engaged in international construction projects. The qualitative data gathered from these interviews underwent systematic analysis to identify important categories and develop theoretical perspectives.FindingsThe findings demonstrate the framework of CTI, which encompasses four essential dimensions that play a significant role in facilitating the successful adjustment of international construction professionals to new technical contexts. These dimensions underscore the multidimensional nature of CTI and offer valuable insights into the necessary capabilities for professionals to thrive in dynamic and globalized construction environments.Originality/valueBy proposing this comprehensive framework, the study contributes to the knowledge and understanding of the technical adjustment process for international construction professionals. It also establishes a foundation for future quantitative research to validate and refine the proposed model, enabling a deeper comprehension of the dynamics involved in professionals' technical adjustment.
Can diplomatic activities promote foreign direct investment? Empirical evidence from China
Authors: Li Jiaen 
Published: October 2024

PurposeThis study investigates the impact of Chinese senior leaders’ diplomatic visits on outward and inward foreign direct investment (OFDI and IFDI, respectively). Additionally, it aims to discern the differential impacts of diplomatic visits on FDI across different Chinese administrations.Design/methodology/approachWe utilize data about the diplomatic visits of Chinese senior leaders to 146 host countries. The dataset was divided into two leadership eras: the tenure of President Hu Jintao and Prime Minister Wen Jiabao from 2003 to 2012 and the period from 2013 to 2021 under President Xi Jinping and Prime Minister Li Keqiang. We employ generalized least squares, lagged effect, and two-stage least squares methods to estimate the econometric model. This analytical framework assesses the influence of high-level diplomatic visits on FDI flows, addressing potential time-serial and endogeneity concerns.FindingsThe findings reveal that senior leaders’ diplomatic visits significantly boost Chinese OFDI. The effect on IFDI in China is not statistically significant. The administrations of Hu and Xi played positive roles in promoting OFDI. However, only Hu’s administration showed a statistically significant positive relationship with IFDI. The result suggests a potential increase in IFDI between China and host countries within two to three years following diplomatic visits.Originality/valueThis study contributes to the understanding of how Chinese senior leaders’ diplomatic activities affect foreign direct investment. It provides a deeper understanding of Chinese senior leaders’ diplomatic efforts to compensate for investment across two administration periods. It offers insights into the potential influence of diplomatic efforts on FDI, enriching the understanding of diplomacy’s role in international business contexts.
Input-output-outcome innovation model: an analysis of the Brazilian manufacturing companies
Authors: Lizarelli Fabiane Letícia , Ishizaka Artur Yuiti , Toledo José Carlos de 
Published: October 2024

PurposeThe objectives of this study are to identify which inputs are most relevant for development and successful introduction of product and process innovations and identify the impacts of these two types of innovation on the performance of Brazilian manufacturing companies.Design/methodology/approachThis study analyzes the relationships between input, output and outcome for a sample of 5,586 Brazilian manufacturing companies by using partial least squares structural equation modeling (PLS-SEM).FindingsThe results indicate that (1) product innovations are favored by internal resources, (2) process innovations are favored by external resources, (3) product innovations mainly affect a range of products offered by companies and (4) process innovations mainly affect performance in manufacturing capacity, flexibility and costs.Practical implicationsBy identifying the main efforts to improve the innovation performance and input-output-outcome relationships, the results can contribute to a better decision-making process for innovation investments and management in companies as well as for policymakers. The results are particularly relevant given that the Brazilian case can serve as a reference for other emerging countries.Originality/valueAnalyses of the innovation in input-output-outcome relationships were performed in a comprehensive way by using a set of variables for defining each construct. This allowed each construct to be better measured, which improved the understanding of the relationships between inputs and outcomes mediated by product and process innovations.
The battle against screen time: a systematic review of hedonic information systems use reduction
Authors: Nascimento Pedro , Oliveira Tiago , Neves Joana 
Published: October 2024

PurposeIn the 21st century, excessive use of hedonic information systems (HIS) has become commonplace, making HIS use reduction a more viable option for many users than complete discontinuation. Even so, there is no systematic revision on this matter. This systematic literature review aims to examine previous studies on HIS use reduction, identify their limitations and point out future research directions.Design/methodology/approachWe adhered to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, ultimately analyzing 52 papers published between 2010 and 2024, with the majority disseminated after 2021.FindingsThe primary findings indicate a gradual shift from focusing on internet research to exploring social networking sites, with consistent attention on gaming and mobile device usage. Moreover, there is notable diversity in the theoretical foundations of scholarly research in this area as well as in the antecedents, consequences and control factors. Additionally, factors such as awareness, social norms, fatigue, privacy concerns and self-efficacy play the most significant roles in reducing the use of HIS. Finally, this article identifies gaps and opportunities in the field and employs science mapping to uncover the four predominant themes that form the basis of this research domain.Originality/valueAs far as we know, this article marks the inaugural comprehensive systematic review of current research on reducing HIS use, intending to make a dual impact. Initially, the authors meticulously outline HIS use reduction systematically and thoroughly, offering theoretical insights. Second, they delve into potential research areas and contributions concerning this phenomenon to address the gap in understanding the effects of reducing HIS usage on individuals.
Risk management committee and earnings management: evidence from an emerging market
Authors: Musa Auwalu , Abdul Latif Rohaida , Abdul Majid Jamaliah 
Published: October 2024

PurposeThis study examines whether the risk management committee (RMC) mitigates earnings management (EM) in Nigeria.Design/methodology/approachThe study used a sample of 365 firm-year observations of Nigerian-listed nonfinancial companies from 2018 to 2022. Driscoll and Kraay’s fixed-effect standard error regression model is used to test the hypotheses.FindingsThe study finds that RMC size, expertise, meeting frequency and membership overlapping with the audit committee have a negative effect on both accrual earnings management (AEM) and real earnings management (REM). While RMC independence is found to have a negative effect on REM. Moreover, additional tests reveal that RMC effectiveness is significantly associated with lower EM practices. Further analysis using the industry level finds that RMC attributes mitigate EM practices in some industries. The results remain after rigorous, robust analysis for endogeneity and alternative regressions.Research limitations/implicationsThis study is limited to a sample of Nigerian-listed nonfinancial service companies for a period of five years, resulting in the non-generalizability of the findings to different contexts as the countries’ internal policies and regulations varied.Practical implicationsThe findings have important implications for regulators, policymakers and investors that a stand-alone RMC can effectively help to evaluate potential risk activities and implement a proper risk management system, thereby mitigating EM practices. The result can help investors, analysts and other stakeholders across the international community in considering RMC information to evaluate potential risk and earnings management practices.Originality/valueFollowing the NCCG 2018 reform in Nigeria that requires listed firms to create a standalone RMC, this study is among the earliest that examines the effect of RMC attributes on EM practices and emerging markets. As such, the findings may draw the attention of regulators and policymakers across the African market and the international community to the monitoring role of RMC attributes in mitigating EM practices.
Flexural behaviour and shear capacity of RC flat plate sections during fire exposure
Authors: Hesien Mohamed , Youssef Maged A. , El-Fitiany Salah 
Published: October 2024

PurposeFire safety is a pivotal requirement in building codes. Prescribed design criteria have been the norm to achieve it, which imposes limitations on engineers, including the inability to accommodate new solutions/materials. The shift towards performance-based design offers the potential to address shortcomings of the prescribed design. However, this shift also significantly increases the workload on structural engineers without a corresponding increase in their engineering fees. Simplified design tools are needed to assist engineers in this transition.Design/methodology/approachThe paper is divided into sections investigating equivalent standard fire duration, thermal deformations, flexural behaviour and shear capacity of flat slabs when exposed to fire. The first section conducts a parametric study correlating equivalent and realistic fire durations using the average internal temperature profile (AITP) method, resulting in statistical equations estimating equivalent fire duration. The second section evaluates thermal deformations and flexural behaviour through a parametric study considering various parameters. This section results in statistical equations estimating thermal deformations and flexural behaviour of flat slab sections during fire exposure. The final section focuses on shear capacity, developing simplified heat transfer formulas and statistical equations predicting compression zone depth reduction. The section presents methodologies predicting flat slab sections' one-way and two-way shear capacities during fire exposure.FindingsStructural engineers can use the proposed methods for daily design work without applying complex heat transfer calculations. When the equivalent standard fire duration is utilized, a flat slab’s thermal deformations, flexural behaviour and shear capacity under an actual fire condition can be calculated. As such, the methods would be highly beneficial in assessing the structural integrity of a building during an active fire incident.Originality/valueThe paper provides engineers with the tools required to evaluate the safety of flat slab sections during fire exposure. The methodologies presented in the paper enable engineers to use performance-based design for slab sections by (1) converting any real fire scenario to a standard fire with an equivalent duration, (2) assessing their thermal behaviour, (3) evaluating their flexural behaviour and (4) evaluating their flexural and shear capacities. The paper concludes with a case study example demonstrating the detailed application of the developed methods.
The person behind the mask: supervisor-subordinate relationships and well-being at work
Authors: Cabral-Cardoso Carlos , Santos Reinaldo Sousa 
Published: October 2024

Purpose
Taking the subordinates’ perspective, this paper aims to explore the supervisor-subordinate relationships and how daily interactions, personal ties and connections with the supervisors contribute more significantly, positively or negatively, to the subordinates’ well-being.

Design/methodology/approach
This exploratory study is based on the thematic analysis of data collected from two rounds of in-depth semi-structured interviews with 21 participants in a Portuguese utility company.

Findings
The subordinates’ perceptions of the nature and quality of their relationships with supervisors were found to have considerable effects on well-being. Positive effects were identified when subordinates feel emotionally supported and believe that supervisors truly care about them and are genuinely willing to listen to their concerns, but the most significant effects on the subordinates’ well-being are produced when the perceived authenticity of the supervisor allows the relationship to evolve into a state of relational closeness, and the subordinates connect with the person-as-real, the human being behind the mask who is playing the supervisory role. These findings reflect features of the cultural setting where the study was conducted.

Originality/value
The study provides evidence to support the argument that a better understanding of supervisor-subordinate relationships and their effects on well-being requires an integrated approach that considers the valuable contributions of different literatures and theoretical frameworks and the multiple dimensions of that relationship, including personal and non-work dimensions. This approach is particularly relevant in cultural contexts where these dimensions might play a critical role in work relations.