bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychiatric hospital treatment of children and adolescents in
New South Wales, Australia: 12-year trends
Authors: Hazell Philip , Sprague Titia , Sharpe Joanne 
Published: February 2016

BackgroundIt is preferable that children and adolescents requiring in-patient care
for mental health problems are managed in age-appropriate facilities. To
achieve this, nine specialist Child and Adolescent Mental Health Services
(CAMHS) in-patient units have been commissioned in New South Wales (NSW)
since 2002.AimsTo examine trends in child and adolescent in-patient admissions since the
opening of these CAMHS units.MethodAnalysis of separation data for under 18-year-olds to CAMHS, adult mental
health and paediatric units for the period 2002 to 2013 in NSW, comparing
districts with and without specialist CAMHS units.ResultsSeparations from CAMHS, adult and paediatric units rose with time, but
there was no interaction between time and health district type
(with/without CAMHS unit). Five of eight health districts experienced
increased separations of under 18-year-olds from adult units in the year
of opening a CAMHS unit. Separations from related paediatric units
increased in three of seven health districts.ConclusionsOpening CAMHS units may be followed by a temporary increase in
separations of young people from adult units, but it does not influence
the flow of patients to non-CAMHS facilities in the longer term.
Adjunctive aripiprazole in risperidone-induced hyperprolactinaemia: double-blind, randomised, placebo-controlled trial
Authors: Raghuthaman G. , Venkateswaran R. , Krishnadas R. 
Published: February 2016

BackgroundHyperprolactinaemia is a troublesome side-effect of treatment with antipsychotics.AimsThis double-blind, placebo-controlled study aimed at examining the effect of adjunctive treatment with 10 mg aripiprazole on prolactin levels and sexual side-effects in patients with schizophrenia symptomatically maintained on risperidone.MethodThirty patients taking risperidone were enrolled into the trial (CTRI/2012/11/003114). Aripiprazole was administered at a fixed daily dose of 10 mg/day for 8 weeks. Serum prolactin was measured at baseline and at 8 weeks. Hyperprolactinaemia-related problems, psychopathology and side-effects were evaluated every 2 weeks.ResultsProlactin levels decreased by 58% in the aripiprazole group compared with an increase by 22% in the placebo group. Prolactin levels normalised in 46% of patients in the aripiprazole group (number needed to treat, NNT=2). Aripiprazole improved erectile dysfunction in five out of six patients. There were no significant differences in change in psychopathology or side-effects between groups.ConclusionsAdjunctive aripiprazole reduced prolactin levels in those treated with risperidone, with no effect on psychopathology and extrapyramidal symptoms. This is a potential treatment for hyperprolactinaemia observed during treatment with second-generation antipsychotics.
Τα γεγονότα εις την περιοχήν Ναούσης-Βέροιας κατά την Επανάστασιν του 1822: (προβλήματα κατά την χρονολόγησιν των)
Authors: Χιονίδης Γεώργιος Χ. 
Published: February 2016

<p>No abstract </p>
Neuroplasticity of Embryonic Brain Tissue in the Rats at Hemodynamic Disturbance
Authors: Гафиятуллина  , Gafiyatullina Gyuzyal , Хананашвили  , Khananashvili Ya. 
Published: February 2016

The investigation was aimed to study of the local cerebral blood flow, partial pressure of oxygen
(рО2) and the character of development of local vascular reactions at embryonic neurotransplant (ENT)
through 4, 8 и 12 months after its transplantation into the barrel field of somatic recipient’s rat brain cortex.
In experiments, a homotopical allotransplantation 17‐day embryonic nervous tissue was conducted in the
Wistar rats. In microareas of embryonic neurotransplant there is an uneven distribution of local cerebral
blood flow and decrease in intensity as compared with intact somatic cortex of control rats. A 4‐month period
after transplantation in the embryonic neuro‐transplantation there is the desired level of hemodynamic
and oxygen supply. Dilatatory ability of micro‐vessels increases in the exercise of regulatory adaptive responses
aimed at regulating the blood flow in nerve tissue, as evidenced by the increasing amplitude of functional
hyperemia and magnitude of the increase of partial oxygen tension. After 8 and 12 months after transplantation,
perfusion intensity and efficiency of ENT micro‐vessels vasodilatation are decreased. The local
functional hyperemia is reducing, the partial pressure of oxygen increases. 4 months after transplantation
unique properties of immature tissue persist; ENT possesses protective properties and provides neuroplastic
effect.
Using of Neural Network for Prognosing of Postoperation Complications
Authors: Карякина  , Karyakina O. , Мартынова  , Martynova N. , Басова  , Basova L. , Кочорова  , Kochorova L. 
Published: February 2016

The paper presents an analysis of results of surgical treatment of patients with chronic lung
disease. To predict the probability of postoperative complications, duration of treatment and the final outcome
after surgical treatment for lung the authors used artificial neural networks (ANN).
Currently in thoracic surgery practically there are no universally accepted prognostic systems, allowing with
high degree of confidence to make the right decision in the treatment strategy for various lung diseases.
The complexity of forecasting in this situation due to the fact that the most information is a subjective expert evaluation by a physician based on his knowledge and experience in the treatment of patients with lung disease.
The results of the research proved that the modeling method based on ANN allows to solve problems
of classification, optimization and forecasting and to give higher prediction accuracy in comparison with
multivariate statistical analysis methods. The article shows that the use of ANN methods enables more accurately
predict the risk of postoperative complications. This accelerates the work of specialists and facilitates
to plan hospitals with high surgical activity.
Monitoring of the Functional State of Patients on the Magnitude of Testing Voltage in the Reference Point
Authors: Зилов  , Zilov V. , Черныш  , Chernysh I. , Василенко  , Vasilenko A. , Фролков  , Frolkov V. 
Published: February 2016

Reference principle of electropuncture diagnostics is based on prior determining the individual
testing voltage using the “reference” point with subsequent measurement of the currents in the acupuncture
points. This approach improves the accuracy of estimation of functional states in comparison with other
methods of electropuncture diagnostics and provides the necessary personalization of diagnostic procedures.
Based on analyzing and summarizing the experience of the clinical use of electropuncture diagnostics
ʺBioreperʺ, its new features are revealed. It is found that the magnitude of testing voltage in a reference point
is a non‐specific indicator of the level of health and the degree of distress the body. It is shown that the measurement
of testing voltage in the reference point allows to monitoring the functional status of patients, to
identifying the severity of pathological changes in the body and to assessing their dynamics during treatment
and rehabilitation. The close correlation between the magnitude of testing voltage and the severity of
pathogenesis reactions of cardiovascular disease, broncho‐pulmonary, digestive and musculoskeletal systems
was revealed. This phenomenon has been confirmed in animal studies (dogs) with the pathology of the stomach, pancreas and gall bladder. It is also found a direct correlation between the magnitude of testing
voltage in the reference point and the severity of pain.
Post-procedural outcomes of vascular closure methods post TAVI: a clinical audit
Authors: Nwosu Winifred Onyinyechi , Shuldham Caroline 
Published: February 2016

Aim:A clinical audit of the post-procedural outcomes in patients having transfemoral transcatheter aortic valve implantation (TAVI), comparing the impact of percutaneous and open surgical access closure of the femoral artery.Method:Using data collected from an NHS hospital database, a retrospective audit was undertaken in February 2014 on all patients who had a transfemoral TAVI between October 2011 and October 2013. Descriptive statistics were used to summarise patient data.Results:Data from 62 patients were included; 31 had open surgical access closure of the femoral artery while the remaining 31 had percutaneous access closure. Median age and interquartile range was 84(8), with 33.8% male and 67.7% female. The median Euroscore was 20.Conclusion:Vascular complications occur after TAVI. However, in this study the incidence was slightly lower with the use of percutaneous access closure compared with open surgical access closure. Patient health outcomes post TAVI are better with percutaneous access closure.
Health service use for cardiovascular disease
Authors: Shiue Ivy 
Published: February 2016

Background: The aim of the present study was to investigate the hospital episode rates in cardiovascular disease by sex and across age groups in order to understand whether and how the use of health services for cardiovascular disease might have changed in recent years in the north-east of England. Methods: Hospital episode data in 2010–2014 covering 5 full calendar years was extracted from Northumbria Healthcare NHS Foundation Trust, which is serving a population of nearly half a million. Hospital episode rates were calculated from all admissions divided by annual and areaspecific population size for each sex and age group, presented per 100 000 person-years using Microsoft Excel. Results: The overall use for each subtype of cardiovascular disease seemed to decrease from 2010 to 2013, but increase from 2013 to 2014. This is particularly apparent in the very old, aged 80 and above, such as in the case of diagnoses owing to essential primary hypertension and angina. For atrial fibrillation and haemorrhagic strokes, a similar situation was observed in the oldest old-aged, 90 and above. For myocardial infarction, heart failure, and cerebral infarction, however, service use seemed to have remained constant over the last 5 years. Of note, there was a huge sex difference in health-service use for cerebral infarction in those aged 90 and above, where there were more women than men admitted. Conclusion: Examining local health-service use owing to the burden of cardiovascular disease annually might help indicate which of its subtypes might require more attention.
Care Certificate Standards 7 and 8: Privacy and dignity; and Fluids and nutrition
Authors: Peate Ian 
Published: February 2016

This article highlights the key issues in ensuring that privacy and dignity feature highly when caring for or supporting people. It also addresses the important role the healthcare assistant and assistant practitioner (HCA and AP) play in ensuring that people they care for are fed and provided with nutrition. Privacy and dignity are closely related to respect and have received much attention in the media over the years. When people are ill or require support, they want care, peace, rest and comfort, in surroundings that are pleasant; they also want to know that the HCA and AP will do all they can to protect their privacy and dignity. The provision of dignity and privacy does not rest with HCA or AP alone, rather is it a responsibility of all staff at all levels. Food and fluids are a requirement for sustaining life. Eating and drinking also bring with it great pleasure, with associated social, cultural and religious functions.
Introduction to the 2015 ATHE Bruce Kirle Memorial Emerging Scholars papers in Music Theater/Dance
Authors: Coleman Bud 
Published: February 2016

Abstract
For over a decade, the Music Theater and Dance Focus Group of the Association for Theater in Higher Education has sponsored the competitive Bruce Kirle Memorial Emerging Scholars panel in Music Theater/Dance at its annual conference. Each year, the winning panellists present their work at the ATHE conference, which was held this year in Montreal, Canada, in August 2015. This year’s panellists, Michelle Bernier, Shiraz Biggie and Phoebe Rumsey, presented their papers in Montreal, and have revised them for publication as articles in Studies in Musical Theatre. Bud Coleman, the respondent to the papers at the ATHE conference, introduces them in this short article.
The effects of number of stems per stool on cutting productivity in coppiced <i>Eucalyptus</i> plantations
Authors: McEwan Andrew , Magagnotti Natascia , Spinelli Raffaele 
Published: February 2016

A time study was conducted to determine whether stem crowding had any impact on harvester productivity in stands. This represents an important element when trying to balance the advantages and disadvantages of coppice management in fast growing plantations designated for mechanized harvesting (i.e. machine felling, delimbing, debarking and cross-cutting). The study material consisted of 446 coppice stems, half of which grew as single stems per stool and half as double stems per stool as a result of different coppice reduction strategies. The dataset was balanced and randomized, with both subsets replicating exactly the same stem size distribution and the single and double stems alternating randomly. Harvester productivity ranged between 6Â and 50 m under bark per productive machine hour, following the variation of tree diameter from 10 to 40 cm at breast height (1.37 m according to South African standards). Regression analysis indicated that both tree size and stem crowding (e.g. one or two stems per stool) had a significant effect on harvester productivity, which increased with stem size and decreased with stem crowding. However, operator experience may overcome the effect of stem crowding, which was not significant when the harvester was manned by a highly experienced operator. In any case, the effect of stem size was much greater than that of stem crowding, which resulted in a cost difference of less than 10%. However, this figure excludes the possible effects of stem crowding on volume recovery and stem development, which should be addressed in the future.Eucalyptus grandis3
D&O Insurance, Corporate Governance and Mandatory Disclosure: An Empirical Legal Study of Taiwan
Authors: Chen Chun-Yuan 
Published: February 2016

Abstract
The purpose of this paper is to test the signal effect of Directors and Officers (D&O) insurance and to analyze the necessity of mandatory disclosure of D&O insurance in Taiwan. D&O insurance is usually viewed as a signal mechanism of insured firms’ corporate governance and thus its mandatory disclosure has been argued. However, there is no complete mandatory disclosure of D&O insurance in the United States and other countries. This issue is not only popular in common law worlds but also sprouting in civil caw jurisdictions such as Taiwan. In the first part of this research, the signal effect of D&O insurance in Taiwan will be empirically tested. The evidence suggests that the information about D&O insurance in Taiwan could statistically and significantly signal the qualities of corporate governance of insured firms. Then, this study addresses the mandatory disclosure of D&O insurance by comparative law and law & economic approaches. This paper compares the regulation about D&O insurance disclosure in the United States, Canada and Taiwan, and find out the reasons affecting the mandatory disclosure of D&O insurance. The Cost and benefit analysis is also applied to discuss whether or not the Canadian mandatory disclosed system should be transplanted. It concludes that the D&O insurance can signal the information of insured firms’ corporate governance, and mandatory disclosure is required and justified. Such interdisciplinary research will provide through recommendations for the Taiwan and other emerging countries in Asia.
Plasma total C-terminal agrin fragment (tCAF) as a marker for kidney function in patients with chronic kidney disease
Authors: Steubl Dominik , Roos Marcel , Hettwer Stefan , Satanovskij Robin , Tholen Susanne , Wen Ming , Schmaderer Christoph , Hasenau Anna-Lena , Luppa Peter , Stecher Lynne , Heemann Uwe , Renders Lutz 
Published: February 2016

AbstractTotal C-terminal agrin fragment (tCAF) is a new biomarker that was previously correlated with kidney function. This article studies the validity of tCAF as a biomarker for kidney function in chronic kidney disease (CKD).Plasma tCAF, serum creatinine (Cr), cystatin C (CyC), blood urea-nitrogen (BUN) concentrations and estimated glomerular filtration rate (eGFR CKD-EPIMean tCAF levels were 1012.2±789.9 pM. tCAF correlated with all biomarkers/eGFR in univariate analysis (eGFR: r=–0.77, Cr: r=0.74, BUN: r=0.66, CyC: r=0.75). Linear regression modeling revealed an excellent coefficient estimate between log tCAF and log eGFR (CKD-EPIIn conclusion, tCAF is a promising biomarker for the assessment of kidney function in CKD patients showing an excellent correlation with eGFR and being less influenced by demographic parameters compared to conventional biomarkers. These preliminary results encourage further evaluation of tCAF in larger CKD cohorts and other clinical settings such as acute renal failure.
Chitosan sponge matrices with β-cyclodextrin for berberine loadinging
Authors: Hnátová Mária , Bakoš Dušan , Černáková L’udmila , Michliková Monika 
Published: February 2016

AbstractBiocompatible polymer sponge materials based on biodegradable natural polymer chitosan, which can be loaded with clinician-selected drugs are still in the centre of interest for their wide use in clinical practice. This study shows possibilities of the technology which combines simple addition of β-cyclodextrin (β-CD), with dialdehyde starch (DAS) as a cross-linking agent of chitosan, to chitosan solutions for subsequent formation of sponge matrix. The advantage of such system is in avoiding chemical modifications and working only with natural substances. It is shown that, in matrix formation during lyophilisation, β-CD molecules tend to accumulate on the surface of the porous matrix structure. This was confirmed by a study of the known inclusion complex of β-CD and salicylic acid (SA) in heptane. The same study was applied to berberine (BER) which can also form an inclusion complex with β-CD in a water solution. Moreover, adsorption of drugs on the surface of the porous structure has to be also taken into account. This enables the production of sponge topical medical preparations useful for sustained release of BER.
Evaluation of DSM-5 and IWG-2 criteria for the diagnosis of Alzheimer’s disease and dementia with Lewy bodies
Authors: Baker Kerry G. 
Published: February 2016

Abstract
Despite differing target audiences and scope it is possible to compare the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) [American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 5th ed. Arlington: American Psychiatric Association, 2013] and the Second International Working Group for New Research Criteria for the Diagnosis of Alzheimer’s Disease (IWG-2) [Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, et al. Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria. Lancet Neurol 2014;13:614–29] diagnostic criteria for both Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). With regard to the diagnosis of AD the principal difference is the inclusion of biomarkers in the IWG-2 diagnostic criteria for this condition. This creates a number of difficulties including a lack of regulatory approval, cultural and other objections to the collection of cerebrospinal fluid (CSF), and a lack of facilities for collection and analysis restricting analysis of CSF proteins to larger tertiary centres [Dubois B, Feldman HH, Jacova C, Hampel H, Molinuevo JL, Blennow K, et al. Advancing research diagnostic criteria for Alzheimer’s disease: the IWG-2 criteria. Lancet Neurol 2014;13:614–29]. With regard to diagnostic criteria for DLB, IWG-2 research criteria designate the co-occurrence of AD and DLB as ‘mixed AD’. However, Alzheimer’s type pathology (ADTP) and Lewy body pathology frequently occur together rendering a separate ‘mixed AD’ category superfluous. The reality is that routine clinical diagnosis of AD and DLB will continue to be based on a thorough general and neurological examination indicating a preponderance of signs and symptoms for one or other of these conditions [Seeley WW, Miller BL. Alzheimer’s disease and other dementias. In: Hauser SL, Josephson SA, editors. Harrison’s neurology in clinical medicine, 3rd ed. New York: McGraw Hill, 2013]. Similarly, AD and DLB research will continue to primarily depend on clinically focussed DSM-5 criteria, making DSM-5 superior to IWG-2 in both clinical and research settings.
Defending laughter: an account of Brazilian court cases involving humor, 1997–2014
Authors: Capelotti João Paulo 
Published: February 2016

AbstractOnce any content is published it is subjected to public scrutiny, and tort actions may be brought by people allegedly offended by it. In most of the western world, there are no prior administrative restraints on freedom of speech, but courts can analyze complaints about various forms of expression and, in cases where the content is deemed abusive, award financial compensation to the victim. Naturally, humorous content is not excluded from this principle, and humorists can therefore face lawsuits. The present study researched all competent courts in Brazil where electronic records were available for the period 1997–2014 in order to present an overview of such cases, focusing on the identity of the claimants and the success of their lawsuits. Analysis of these data allowed some trends and inconsistencies in how Brazilian judges deal with cases involving humor to be identified. The first observation is that courts tend to favor humor that is closer to journalistic comment, i. e., humorous pieces relating to subjects of public interest. Humor, however, is not and cannot be limited to this particular type of humor. The second observation is that many judges punish humor that in their view seems to be “exaggerated,” disregarding the fact that exaggeration and unreasonableness are trademarks of humor. Thus, conservative and highly personal positions on the part of judges create an environment of uncertainty surrounding cases involving humor and freedom of speech. It is suggested that better attention to precedents set by Brazilian Higher Courts and a degree of common sense (including a sense of humor) on the part of the judiciary would help overcome judicial bias against humorists.
Solving Large-Deflection Problem of Spatial Beam with Circular Cross-Section Using an Optimization-Based Runge–Kutta Method
Authors: Li Geng , Jia Jianyuan , Chen Guimin 
Published: February 2016

Abstract
Based on the Bernoulli–Euler beam theory, the nonlinear governing differential equations (GDEs) for a spatially deflected beam with circular cross-section are formulated, which are then reduced to first-order differential equations to be compatible with Runge–Kutta method. With the boundary conditions of a spatial beam, the governing equations are treated as an initial value problem (IVP) of ordinary differential equations. A Runge–Kutta method combined with an unconstrained optimization algorithm (RKUO) is presented to solve the IVP. The approach for determining the orientation of the cross-section plane at any position on the deflected beam is also provided. Finally, the comparison between the RKUO results and those achieved using nonlinear finite element (NFE) analysis and spatial pseudo-rigid-body model validate the accuracy and effectiveness of RKUO. The results also demonstrated the unique capabilities of RKUO to solve large spatial deflection problems that are outside the range of nonlinear finite element model.