bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Go Near and Join Thyself to This Chariot…”: African Pneumatic Movements and Transformational Discipleship
Authors: Asamoah‐Gyadu J. Kwabena 
Published: December 2017

AbstractChristian religious innovation has been ongoing in Africa since the early 20th century. It started with indigenous charismatic prophets calling on people to turn over their old deities and submit to the lordship of Jesus Christ. The ministries of these itinerant prophets led to mass conversions culminating in the formation of what became known as the African independent/instituted/initiated churches (AICs). For the best part of the 20th century the AICs defined what counted as Christian in an African indigenous sense. The argument of this article is that the acronym AICs has, since the closing decades of the 20th century, acquired a much broader meaning to include the new Pentecostal/charismatic movements and churches that have burgeoned across the continent. Their trademarks include youthful urban‐centred congregations, media‐driven ministries, and the preaching of a gospel of prosperity. The contributions of both the classical AICs and the contemporary Pentecostals to African Christianity have been phenomenal. As Christian churches, however, we ought to evaluate them not just in terms of numerical or sociological impact, but most especially in terms of transformational discipleship. There is much to celebrate in transformational discipleship as far as the ministries of these African Reformation movements are concerned, but there as yet remain areas of concern that need to be dealt with for the optimization of Christian impact in Africa.
Black Racial Stereotypes and Victim Blaming: Implications for Media Coverage and Criminal Proceedings in Cases of Police Violence against Racial and Ethnic Minorities
Authors: Dukes Kristin Nicole , Gaither Sarah E. 
Published: December 2017

AbstractPosthumous stereotypical media portrayals of Michael Brown and other racial and ethnic minority victims of police violence have sparked questions about the influence of racial stereotypes on public opinions about their deaths and criminal proceedings for their killers. However, few studies have empirically investigated how the specific type of information released about a victim impacts opinions surrounding such incidents. Participants (N = 453) read about an altercation that resulted in a shooting death where the race of the victim and shooter (Black vs. White) was randomly assigned. Participants learned either negative, Black male stereotypic or positive, Black male counterstereotypic information about the victim. Next, participants appraised levels of fault and blame, sympathy and empathy for the victim and shooter, and indictment recommendations for the shooter. Findings suggest that the type of information released about a victim can significantly sway attitudes toward the victim and the shooter. Implications for media portrayals of racial/ethnic minority victims of police violence and its impact on criminal sentencing are discussed.
Do panelists memorize products when performing descriptive analysis on few products?
Authors: Lestringant Pauline , Delarue Julien , Heymann Hildegarde 
Published: December 2017

AbstractFew studies have investigated the impact of the number of samples on the descriptive analysis (DA) process and results. One may hypothesize that when training on and evaluating small product sets, panelists memorize the products instead of actually evaluating the samples based on their perceptions of the attributes. In this study, we tested whether products were recognized during the training and evaluation phases of separate ketchup and lemonade panels. After performing a full DA task, panelists did a recognition test, in which they were asked to estimate the number of products they evaluated and which ones they recognized from a larger sample set. Panelists did not realize how many different samples they tasted, neither during training nor evaluation. Yet, they were able to recognize samples they had previously tasted in DA. Similarities among products led to mistakes. However, samples that were very different from others were not better recognized.Practical applicationsThis study is a first attempt at evaluating the extent of product recognition in a realistic descriptive analysis context. The goal of sensory profiles is to measure human perception of products, which can be biased by memory effects. Since memorization may depend on the number of products panelists are trained on, we tested a “worst case scenario” with only four products during the training phase. This is relevant to many situations in which small sample sizes occur: a 2 x 2 experimental design, few innovative products present on the market, or limited number of prototypes available.
Literature—Technology—Media: Towards a new technography
Authors: Purdon James 
Published: December 2017

AbstractThe recent medial turn in the humanities has brought with it an increasing focus on systems, devices, protocols, and other aspects of the technological mediation of culture. This article considers the two most prominent instances of technological inquiry—media archaeology and the theory of cultural techniques—in order to show how literary studies can learn from and contribute to the ongoing re‐evaluation of the relationship between technology and culture. On the basis of a philological argument tracing the emergence of the concept of “technology” in classical rhetoric and its transformation during the first Industrial Revolution, the article develops a critique of the Enlightenment distinction between technology and discursivity and calls for a new “technographic” understanding of the dialectic between the two.
When Increased Turnout Matters: Simulating the Partisan Impact of Full Turnout in Senate and Gubernatorial Elections
Authors: Burmila Edward M. , Birkhead Nathaniel A. 
Published: December 2017

What if everyone voted? There is consensus that increased turnout generally, but not always, benefits Democrats, but recent evidence suggests that it is unlikely to change election outcomes considering the paucity of close races. For the first time, we examine this question using gubernatorial races along with Senate races from 2008 and 2010, estimating the behavior of nonvoters based on individual‐level data from known voters. We find that the substantive effect of full turnout is understated, particularly in close gubernatorial races. As these races determine partisan control of executive branches, we demonstrate that full turnout would result in more politically meaningful changes than suggested in previous research focusing only on Senate or presidential elections. While the empirical consequences of increased turnout are well understood, our findings suggest that the substantive effects continue to be understated.Related Articles

Stockemer, Daniel, and
Stephanie Parent. 2014. “.” Politics & Policy 42 (): 221‐245. http://onlinelibrary.wiley.com/doi/10.1111/polp.12067/abstract

Southwell, Priscilla. 2011. “.” Politics & Policy 39 (): 979‐996. http://onlinelibrary.wiley.com/doi/10.1111/j.1747-1346.2011.00330.x/abstract

Stockemer, Daniel. 2013. “.” Politics & Policy 41 (): 189‐212. http://onlinelibrary.wiley.com/doi/10.1111/polp.12012/abstract
A meta‐analysis of the indirect impact of foreign direct investment in old and new EU member states: Understanding productivity spillovers
Authors: Bruno Randolph Luca , Cipollina Maria 
Published: December 2017

AbstractIn this paper, we summarise, combine and explain recent findings from firm‐level empirical literature focusing on the indirect impact of foreign direct investment (FDI) on economic performance, measured as productivity, in the Enlarged Europe. We have reviewed 52 quantitative studies, released between 2000 and 2015 and codified 1,133 estimates. We run a regression of regressions which measures the strength of the FDI–productivity relationship. Taking advantage of large number of high‐quality studies on FDI and its role in explaining the growth in firms’ productivity in Europe, we adopt recent meta‐regression analysis methods—funnel asymmetry and precision estimate tests and precision‐effect estimate with standard errors—to explain the heterogeneous impact of FDI. This paper assesses the country‐specific impact of FDI on firms’ performance, after taking publication selection bias, econometric modelling and the individual studies’ characteristics fully into account. Our results show that on average FDI has a positive indirect impact on productivity. The impact is especially significant in selected European countries, and we interpret this as a sign of better absorptive capacities in those countries.
Evaluation of efficacy of repeated decontamination and sterilization of single‐incision laparoscopic surgery ports intended for 1‐time use
Authors: Petrovsky Brian , Monnet Eric 
Published: December 2017

AbstractObjectiveTo determine the efficacy of repeated decontamination and sterilization of a disposable port intended for 1‐time use during single‐incision laparoscopy.Study DesignExperimental; prospective, controlled design.MethodsSix single‐access ports used 4 times and 6 single‐access ports used 8 times to perform various clean, minimally invasive surgeries were evaluated. Ports were decontaminated in an enzymatic cleaner (dilution, 3:100) and cleaned with a scrub brush for 5 minutes. The ports were then sterilized with hydrogen peroxide vapor for 50 minutes using a standard protocol at a concentration of 6 mg/L, followed by a vapor diffusion phase. Samples taken from the foam, insufflating tubing, and rigid cannula portion of each port were collected with aseptic technique for aerobic–anaerobic cultures. Port material samples were set up on a tryptic soy agar plate with 5% sheep blood, a MacConkey agar plate, and a Columbia agar plate with 5% sheep blood (CAP). Anaerobic isolate cultures were set up on Centers for Disease Control and Prevention (CDC) blood agar and CAP.ResultsNone of the ports used 4 times had positive bacteriologic culture. Two of the ports used 8 times had a light growth of bacteria. The first positive sample cultured Staphylococcus spp. and Micrococcus spp. The second positive sample cultured Staphylococcus epidermidis. The positive cultures were obtained from the foam component in an enriched broth.ConclusionSingle‐incision ports could be used safely 4 times and pose a low risk of infection to the patient under conditions of this study.
Biosorption of nickel ions from aqueous solutions by natural and modified peanut husks: equilibrium and kinetics
Authors: Burevska Katerina Atkovska , Memedi Hamdije , Lisichkov Kiril , Kuvendziev Stefan , Marinkovski Mirko , Ruseska Gordana , Grozdanov Anita 
Published: December 2017

AbstractThe toxicity and non‐biodegradation of heavy metals, as well as their tendency to accumulate in the soils, water resources and the living organisms, makes them the significant environmental pollutants. Therefore, the reduction and elimination of heavy metal ions from aqueous systems is very important from the ecological, nutritional and environmental reasons. The aim of this study is to investigate whether the natural peanut husks, an agricultural waste, and their chemically modified form are capable to remove Ni(II) ions from aqueous solutions using batch method and to compare their efficiency. The effects of the mass of the natural peanut husks and the initial pH of the solution were studied to find the optimal conditions for maximal removal of Ni(II) ions. MATLAB/Curve Fitting Toolbox was implemented to determine the adequate adsorption isotherm as well as to optimise the equilibrium state of the investigated systems.
In vitro invasion capacity of Salmonella Typhimurium DT9 isolates sourced from humans and layer hen environments
Authors: McWhorter A. R. , Phan G. , Hocking H. , Chousalkar K. K. 
Published: December 2017

SummaryIn Australia, Salmonella Typhimurium definitive type 9 is frequently isolated during foodborne outbreaks of salmonellosis. Multiple‐locus variable number tandem repeat analysis (MLVA) trace back investigations frequently identify isolate distribution patterns that may be epidemiologically linked to disease outbreaks. In this study, the in vitro virulence potential of S. Typhimurium DT9 isolates possessing different MLVA patterns (03 15 07 11 550, 03 24 11 10 523, 03 15 08 11 550 and 03 14 08 11 550) isolated from either humans or layer hens was assessed using a human colon carcinoma cell line. Four strains per MLVA from each host for a total of 32 isolates were included in these experiments. Bacteria were grown to stationary phase and added to cells at a multiplicity of infection of 100. Across all isolates, mean percent recovery ranged from 7.1 ± 1.1 to 33.3 ± 7.1%. The layer hen isolate, KC900 (MLVA profile 03 15 08 11 550), exhibited the greatest invasion with a mean percent recovery of 33.3 ± 7.1%. Overall, layer hen isolates of S. Typhimurium DT9 had significantly higher invasion into Caco2 cells than human isolates (p = .0021). RAPD and enterobacterial repetitive intergenic consensus genomic fingerprinting was also performed. Irrespective of source, the SalmonellaDT9 isolates included in this study exhibited similar fingerprint patterns.
Metagenome Sequence of a Microbial Community from the Gold Mine Tailings in the Kuzbass Area, Russia
Authors: Mardanov Andrey V. , Beletsky Alexey V. , Ivasenko Denis A. , Karnachuk Olga V. , Ravin Nikolai V. 
Published: December 2017

ABSTRACT

The metagenome of a microbial community of the sediments from a highly acidic iron-rich puddle at the tailings dump of the Komsomolskaya gold mine in the Kuzbass area, Siberia, Russia, was sequenced. Binning of contigs yielded a near-complete genome of the dominant bacterium, representing a novel deep lineage of
Deltaproteobacteria
.
Subthalamotomy for Parkinson’s disease: clinical outcome and topography of lesions
Authors: Rodriguez-Rojas Rafael , Carballo-Barreda Maylen , Alvarez Lazaro , Guridi Jorge , Pavon Nancy , Garcia-Maeso Ivan , Mací­as Raul , Rodriguez-Oroz Maria C , Obeso Jose Angel 
Published: December 2017

ObjectiveSubthalamotomy is an effective alternative for the treatment of Parkinson’s disease (PD). However, uncertainty about the optimal target location and the possibility of inducing haemichorea-ballism have limited its application. We assessed the correlation between the topography of radiofrequency-based lesions of the subthalamic nucleus (STN) with motor improvement and the emergence of haemichorea-ballism.MethodsSixty-four patients with PD treated with subthalamotomy were evaluated preoperatively and postoperatively using the Unified Parkinson’s Disease Rating Scale motor score (UPDRSm), MRI and tractography. Patients were classified according to the degree of clinical motor improvement and dyskinesia scale. Lesions were segmented on MRI and averaged in a standard space. We examined the relationship between the extent of lesion-induced disruption of fibres surrounding the STN and the development of haemichorea-ballism.ResultsMaximum antiparkinsonian effect was obtained with lesions located within the dorsolateral motor region of the STN as compared with those centre-placed in the dorsal border of the STN and the zona incerta (71.3%, 53.5% and 20.8% UPDRSm reduction, respectively). However, lesions that extended dorsally beyond the STN showed lower probability of causing haemichorea-ballism than those placed entirely within the nucleus. Tractography findings indicate that interruption of pallidothalamic fibres probably determines a low probability of haemichorea-ballism postoperatively.ConclusionsThe topography of the lesion is a major factor in the antiparkinsonian effect of subthalamotomy in patients with PD. Lesions involving the motor STN and pallidothalamic fibres induced significant motor improvement and were associated with a low incidence of haemichorea-ballism.
NKG2D-Based CAR T Cells and Radiotherapy Exert Synergistic Efficacy in Glioblastoma
Authors: Weiss Tobias , Weller Michael , Guckenberger Matthias , Sentman Charles L. , Roth Patrick 
Published: December 2017

Abstract
Chimeric antigen receptor (CAR) T-cell therapy is an emerging immunotherapy against several malignancies including glioblastoma, the most common and most aggressive malignant primary brain tumor in adults. The challenges in solid tumor immunotherapy comprise heterogenously expressed tumor target antigens and restricted trafficking of CAR T cells to and impaired long-term persistence at the tumor site, as well as the unaddressed integration of CAR T-cell therapy into conventional anticancer treatments. We addressed these questions using a NKG2D-based chimeric antigen receptor construct (chNKG2D) in fully immunocompetent orthotopic glioblastoma mouse models. ChNKG2D T cells demonstrated high IFNγ production and cytolytic activity in vitro. Upon systemic administration in vivo, chNKG2D T cells migrated to the tumor site in the brain, did not induce adverse events, prolonged survival, and cured a fraction of glioma-bearing mice. Surviving mice were protected long-term against tumor rechallenge. Mechanistically, this was not solely the result of a classical immune memory response, but rather involved local persistence of chNKG2D T cells. A subtherapeutic dose of local radiotherapy in combination with chNKG2D T-cell treatment resulted in synergistic activity in two independent syngeneic mouse glioma models by promoting migration of CAR T cells to the tumor site and increased effector functions. We thus provide preclinical proof-of-concept of NKG2D CAR T-cell activity in mouse glioma models and demonstrate efficacy, long-term persistence, and synergistic activity in combination with radiotherapy, providing a rationale to translate this immunotherapeutic strategy to human glioma patients.
Significance: These findings provide evidence for synergy of conventional anticancer therapy and CAR T cells and heralds future studies for other treatment combinations. Cancer Res; 78(4); 1031–43. ©2017 AACR.
Peptide Blocking of PD-1/PD-L1 Interaction for Cancer Immunotherapy
Authors: Li Chunlin , Zhang Nengpan , Zhou Jundong , Ding Chen , Jin Yaqing , Cui Xueyuan , Pu Kefeng , Zhu Yimin 
Published: December 2017

Abstract
Immunotherapy has become a promising alternative therapeutic approach for cancer patients. Interruption of immune checkpoints, such as CTLA-4 and PD-1, has been verified to be a successful means for cancer therapy in clinical trials. mAb targeting PD-L1 has been approved to treat urothelial carcinoma, non–small cell lung cancer, or Merkel cell carcinoma by the FDA. However, the high cost of the antibody can limit its application. In our study, targeting PD-L1 peptide (TPP-1), which specifically binds to PD-L1 with high affinity, was identified through bacterial surface display methods. Using a T-cell activation assay and mixed lymphocyte reaction, TPP-1 was verified to interfere with the interaction of PD-1/PD-L1. To examine the inhibitory effect of TPP-1 on tumor growth in vivo, a xenograft mouse model using H460 cells was established. The growth rate of tumor masses in TPP-1 or PD-L1 antibody–treated mice was 56% or 71% lower than that in control peptide–treated mice, respectively, indicating that TPP-1 inhibits, or at least retards, tumor growth. IHC of the tumors showed that IFNγ and granzyme B expression increased in the TPP-1 or PD-L1 antibody–treated groups, indicating that TPP-1 attenuates the inhibitory effect of PD-L1 on T cells and that T cells may get reactivated. On the basis of our data, TPP-1 peptide could work as an alternative to antibodies for tumor immunotherapy. Cancer Immunol Res; 6(2); 178–88. ©2017 AACR.
Novel Mitochondria-Targeting Peptide in Heart Failure Treatment
Authors: Daubert Melissa A. , Yow Eric , Dunn Gary , Marchev Sotir , Barnhart Huiman , Douglas Pamela S. , O’Connor Christopher , Goldstein Sidney , Udelson James E. , Sabbah Hani N. 
Published: December 2017

Background
Mitochondrial dysfunction and energy depletion in the failing heart are innovative therapeutic targets in heart failure management. Elamipretide is a novel tetrapeptide that increases mitochondrial energy; however, its safety, tolerability, and therapeutic effect on cardiac structure and function have not been studied in heart failure with reduced ejection fraction.

Methods and Results

In this double-blind, placebo-controlled, ascending-dose trial, patients with heart failure with reduced ejection fraction (ejection fraction, ≤35%) were randomized to either a single 4-hour infusion of elamipretide (cohort 1 [n=8], 0.005; cohort 2 [n=8], 0.05; and cohort 3 [n=8], 0.25 mg·kg
−1
·h
−1
) or placebo control (n=12). Safety and efficacy were assessed by clinical, laboratory, and echocardiographic assessments performed at pre-, mid- and end-infusion and 6-, 8-, 12- and 24-hours postinfusion start. Peak plasma concentrations of elamipretide occurred at end-infusion and were undetectable by 24 hours postinfusion. There were no serious adverse events. Blood pressure and heart rate remained stable in all cohorts. Compared with placebo, a significant decrease in left ventricular end-diastolic volume (−18 mL;
P
=0.009) and end-systolic volume (−14 mL;
P
=0.005) occurred at end infusion in the highest dose cohort.

Conclusions
This is the first study to evaluate elamipretide in heart failure with reduced ejection fraction and demonstrates that a single infusion of elamipretide is safe and well tolerated. High-dose elamipretide resulted in favorable changes in left ventricular volumes that correlated with peak plasma concentrations, supporting a temporal association and dose–effect relationship. Further study of elamipretide is needed to determine long-term safety and efficacy.

Clinical Trial Registration

URL:
https://www.clinicaltrials.gov
. Unique identifier: NCT02388464.
Ten-Year Mortality in the WISE Study (Women’s Ischemia Syndrome Evaluation)
Authors: Kenkre Tanya S. , Malhotra Pankaj , Johnson B. Delia , Handberg Eileen M. , Thompson Diane V. , Marroquin Oscar C. , Rogers William J. , Pepine Carl J. , Bairey Merz C. Noel , Kelsey Sheryl F. 
Published: December 2017

Background—
The WISE study (Women’s Ischemia Syndrome Evaluation) was a prospective cohort study of 936 clinically stable symptomatic women who underwent coronary angiography to evaluate symptoms and signs of ischemia. Long-term mortality data for such women are limited.

Methods and Results—
Obstructive coronary artery disease (CAD) was defined as ≥50% stenosis on angiography by core laboratory. We conducted a National Death Index search to assess the mortality of women who were alive at their final WISE contact date. Death certificates were obtained. All deaths were adjudicated as cardiovascular or noncardiovascular by a panel of WISE cardiologists masked to angiographic data. Multivariate Cox proportional hazards regression was used to identify significant independent predictors of mortality. At baseline, mean age was 58±12 years; 176 (19%) were non-white, primarily black; 25% had a history of diabetes mellitus, 59% hypertension, 55% dyslipidemia, and 59% had a body mass index ≥30. During a median follow-up of 9.5 years (range, 0.2–11.5 years), a total of 184 (20%) died. Of these, 115 (62%) were cardiovascular deaths; 31% of all cardiovascular deaths occurred in women without obstructive CAD (<50% stenosis). Independent predictors of mortality were obstructive CAD, age, baseline systolic blood pressure, history of diabetes mellitus, history of smoking, elevated triglycerides, and estimated glomerular filtration rate.

Conclusions—
Among women referred for coronary angiography for signs and symptoms of ischemia, 1 in 5 died from predominantly cardiac pathogeneses within 9 years of angiographic evaluation. A majority of the factors contributing to the risk of death seem to be modifiable by existing therapies. Of note, 1 in 3 of the deaths in this cohort occurred in women without obstructive CAD, a condition often considered benign and without guideline-recommended treatments. Clinical trials are needed to provide treatment guidance for the group without obstructive CAD.