bluuebunny/crossref_metadata_2025_split huggingface dataset:
Miniaturized printed YAGI‐Uda antenna with high directivity for long range UHFRFID item tracking systems
Authors: Kim J.‐H. , Jeong M.‐G. , Bae S.‐H. , Lee W.‐S. 
Published: December 2016

ABSTRACTA miniaturized printed Yagi‐Uda antenna with high directivity for long‐range ultra‐high‐frequency radio frequency identification item tracking systems is presented. The proposed antenna consists of a meandered driven element and a reflector to obtain a compact size and high directivity. Using a printed microstrip balun, the proposed antenna is fed by a 50‐Ω microstrip line in a printed circuit board. The peak gain and maximum front‐to‐back ratio of the proposed antenna are ∼4.5 dBi and 17 dB at the authorized UHF RFID band in Korea, respectively. The antenna physical size is 80 × 45.5 mm2 (approximately 0.25λ0 × 0.14 λ0 at 920 MHz). © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:439–441, 2017
Experimental validation of a single‐photodiode receiver for VLC systems using color shift keying modulation
Authors: Luna Rivera Jose M. , Guerra Victor , Rabadan Jose , Perez‐Jimenez Rafael , Suarez‐Rodriguez Cristo 
Published: December 2016

ABSTRACTThis letter reports the first experimental results obtained from a recently proposed single‐photodiode receiver for visible light communications (VLC) using color shift keying (CSK) modulation. This novel detection scheme has the potential to reduce the implementation cost by two‐thirds compared to the CSK‐based receiver structure introduced in the VLC IEEE 802.15.7 standard. A proof of concept is performed to demonstrate its practical feasibility and advantages towards the deployment of VLC systems. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:428–432, 2017
All electronic propagation loss measurement and link budget analysis for 350 GHz communication link
Authors: Bhardwaj Shubhendu , Nahar Niru K. , Volakis John L. 
Published: December 2016

ABSTRACTIn this work, we measure the propagation losses for estimating the performance of a communication link in the frequency band of 350 GHz. The losses are measured by having a transmitter and receiver at varying distances upto 8.5 m. Due to limited ability to move the transmitter and receiver, reflection methods are employed. Using this simple method, we show the presence of water absorption lines in the spectra at 380 and 448 GHz. We also study the data‐rate enhancement using dielectric lenses. Finally, using the measured data, we estimate that data‐ rates of 1 Gbps for 8.5 m and 100 Gbps for 1 m distance are possible via a communication link at 350 GHz. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:415–423, 2017
A K‐band low phase noise and low power CMOS voltage‐controlled oscillator
Authors: Tsai Jeng‐Han , Lin Yu‐Zhe , Kuo Yin‐Ting 
Published: December 2016

ABSTRACTA K‐band differential cross‐coupled inductance‐ capacitance (LC) voltage‐controlled oscillator (VCO) is implemented in 0.18‐μm CMOS process. To accomplish high quality (Q) factor LC‐tank at K‐band, a slab inductor with high Q is adopted. The VCO can be tuned from 23.1 to 23.38 GHz and the core dc power consumption is 11.33 mW from 1 V power supply. The phase noise is −109.04 dBc/Hz at 1 MHz offset, and the calculated figure of merit (FoM) is −185.79 dBc/Hz. At low supply voltage mode of 0.65 V, the phase noise is −106.015 dBc/Hz at 1 MHz offset and the FoM is −189.76 dBc/Hz. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:362–366, 2017
Design of multiband electromagnetic wave absorber based on a periodic surface for electromagnetic wave measurement facility applications
Authors: Sim Dong‐Uk , Kwon Jong‐Hwa , Park Seong‐Ook 
Published: December 2016

ABSTRACTIn this paper, the periodic structure‐based absorber operating at dual‐band or more for applying to new electromagnetic wave measurement facility that does not contain a conventional pyramidal absorber is presented. To achieve the objective, the absorber structure takes the format of two‐layer periodic surfaces. Based on the logical design principles, the parametric study results to obtain the desired performance and the final experimental result are addressed. The measured result shows a broadband reflectivity characteristic from 0.60 to 3.27 GHz on the basis of below −10 dB. As a result, the absorber shows the performance supporting CDMA, WCDMA, and WLAN bands in the electromagnetic wave measurement facility. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:478–481, 2017
Hot‐spot temperature and temperature decay rate measurement in the oil immersed power transformer through FBG based quasi‐distributed sensing system
Authors: Deng Jian‐Gang , Nie De‐Xin , Pi Ben‐Xi , Xia Li , Wei Li 
Published: December 2016

ABSTRACTThis work demonstrates a quasi‐distributed sensing method to obtain the accurate location and temperature value of hot‐spot by placing Fiber Bragg Grating sensors in the conductor wires of transformer's windings. The quasi‐distributed temperature measuring system can support the demodulation of up to 218 FBGs, and has the ability to obtain the temperature decay rates of windings, strips, iron cores, and top oil in a 35 kV/4000 kVA oil immersed power transformer through a temperature‐rise test. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:472–475, 2017
High accuracy terahertz time‐domain system for reliable characterization of photoconducting antennas
Authors: Abdulmunem Oday Mazin , Born Norman , Mikulics Martin , Balzer Jan Christof , Koch Martin , Preu Sascha 
Published: December 2016

ABSTRACTWe report on a terahertz (THz) time‐domain system to characterize photoconductive THz emitters and detectors, that is designed for highest reproducibility. This system is excellently suited for studying the performance of THz sources and detectors in a systematic manner, either by varying the substrate materials or the geometrical parameters of metallic antenna contacts building a photoconductive switch. After confirming the reproducibility and stability of the system with errors of only 1.9% (over 3 h) and 2.6% (over 9 days), we use the system to compare the performance of five low temperature grown (LT) GaAs wafers with growth temperatures between 200°C and 300°C. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 59:468–472, 2017
Functional and structural microanatomy of the fetal sciatic nerve
Authors: Creze Maud , Zaitouna Mazen , Krystel Nyangoh Timoh , Diallo Djibril , Lebacle Cédric , Bellin Marie‐France , Ducreux Denis , Benoit Gérard , Bessede Thomas 
Published: December 2016

ABSTRACTIntroductionThe ultrastructure of a nerve has implications for surgical nerve repair. The aim of our study was to characterize the fascicular versus fibrillar anatomy and the autonomic versus somatic nature of the fetal sciatic nerve (SN).MethodsImmunohistochemistry for vesicular acetylcholine transporter, tyrosine hydroxylase, and peripheral myelin protein 22 was performed to identify cholinergic, adrenergic, and somatic axons, respectively, in the human fetal SN. Two‐dimensional (2D) analysis and 3D reconstructions were performed.ResultsThe fetal SN is composed of one‐third stromal tissue and two‐thirds neural tissue. Autonomic fibers are predominant over somatic fibers within the neural tissue. The distribution of somatic fibers is initially random, but then become topographically organized after intra‐ and interfascicular rearrangements have occurred within the nerve.ConclusionsThe fetal model presents limitations but enables illustration of the nature of the nerve fibers and the 3D fascicular anatomy of the SN. Muscle Nerve 56: 787–796, 2017
Is thyrotoxic periodic paralysis a disease caused by muscle membrane dysfunction?
Authors: Son Yoo‐Ri , Kim Nam‐Hee , Kim Dong‐Gun , Park Kyung‐Seok 
Published: December 2016

ABSTRACTIntroduction: Thyrotoxic periodic paralysis (TPP) is characterized by recurrent episodes of reversible paralysis with hyperthyroidism. It is clinically similar to hypokalemic periodic paralysis (HOPP), which features significant ion‐channel dysfunction and reduced muscle fiber conduction velocity (MFCV). However, the muscle membrane function in TPP is not known. Methods: For 13 patients with TPP and 15 age‐matched controls, clinical assessment and serial neurophysiological testing, including nerve conduction, prolonged exercise (PE) testing, and MFCV. were performed. Results: MFCV values were elevated up to 1 year from the paralytic attack in TPP patients. In the group with a positive PE test, MFCV values were higher. There was no significant relationship between MFCV values and either hypokalemia or hyperthyroidism. Conclusions: Although clinical manifestations in TPP are similar to those observed in HOPP, TPP appears to feature an alternate pathogenic mechanism. Specifically, MFCV values increased rather than decreased. Further studies are needed to support these findings. Muscle Nerve, 2016 Muscle Nerve 56: 780–786, 2017
Quantification of human upper extremity nerves and fascicular anatomy
Authors: Brill Natalie A. , Tyler Dustin J. 
Published: December 2016

ABSTRACTIntroductionIn this study we provide detailed quantification of upper extremity nerve and fascicular anatomy. The purpose is to provide values and trends in neural features useful for clinical applications and neural interface device design.MethodsNerve cross‐sections were taken from 4 ulnar, 4 median, and 3 radial nerves from 5 arms of 3 human cadavers. Quantified nerve features included cross‐sectional area, minor diameter, and major diameter. Fascicular features analyzed included count, perimeter, area, and position.ResultsMean fascicular diameters were 0.57 ± 0.39, 0.6 ± 0.3, 0.5 ± 0.26 mm in the upper arm and 0.38 ± 0.18, 0.47 ± 0.18, 0.4 ± 0.27 mm in the forearm of ulnar, median, and radial nerves, respectively. Mean fascicular diameters were inversely proportional to fascicle count.ConclusionDetailed quantitative anatomy of upper extremity nerves is a resource for design of neural electrodes, guidance in extraneural procedures, and improved neurosurgical planning. Muscle Nerve 56: 463–471, 2017
A 6‐node triangular solid‐shell element for linear and nonlinear analysis
Authors: Ko Yeongbin , Lee Phill‐Seung 
Published: December 2016

SummaryIn this paper, we present an effective 6‐node triangular solid‐shell element (MITC‐S6), with particular attention on shear locking and thickness locking. To alleviate shear locking, the assumed transverse strain field of the MITC3+ shell element is used while modifying the bending enhancement mechanism. Thickness locking is treated using the assumed and enhanced strain methods for thickness strain. Two independent enhancements of strains are applied: The in‐plane and transverse shear strain fields are enhanced using the strain fields obtained from a bubble interpolation function for in‐plane translations, and the thickness strain field is enhanced for linear variation in the thickness direction. The general three‐dimensional material law is employed. The proposed element passes all the basic tests including zero‐energy mode, patch, and isotropy tests. Excellent performance is observed in various linear and nonlinear benchmark tests, wherein its performance is compared with that of existing 6‐node triangular and 8‐node quadrilateral solid‐shell elements. Copyright © 2016 John Wiley & Sons, Ltd.
INSIGHT responsive parenting intervention is associated with healthier patterns of dietary exposures in infants
Authors: Hohman Emily E. , Paul Ian M. , Birch Leann L. , Savage Jennifer S. 
Published: December 2016

ObjectiveTo determine whether a responsive parenting (RP) intervention affects infant dietary patterns.MethodsPrimiparous mother‐newborn dyads (n = 291) were randomized to the Intervention Nurses Start Infants Growing on Healthy Trajectories (INSIGHT) RP intervention or control. Curricula were delivered at nurse home visits at ages 3, 16, 28, and 40 weeks. RP group feeding guidance advised responsive feeding, delayed introduction of solids, repeated exposure to novel foods, and age‐appropriate portion sizes. Latent class analysis identified patterns of dietary exposure at 9 months. Class membership at 9 months was used to predict BMI percentile at 2 years.ResultsFive dietary patterns were identified: “Breastfed, Fruits and Vegetables,” “Breastfed, Low Variety,” “Formula, Fruits and Vegetables,” “Formula, Low Variety,” and “Formula, High Energy Density.” Over 60% of infants had patterns low in fruits and vegetables or high in energy‐dense foods. RP group infants were less likely than control to be in the “Formula, Low Variety” class (OR = 0.40, 95% CI 0.23–0.71) or “Formula, High Energy Density” class (OR = 0.28, 95% CI 0.12–0.61) relative to the “Formula, Fruits and Vegetables” class. Dietary pattern at 9 months was significantly associated with BMI percentile at 2 years.ConclusionsWhile a majority of infants consumed diets low in fruits and vegetables, the INSIGHT RP intervention was associated with healthier dietary patterns.
Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders
Authors: Shih Barbara B , Nirmal Ajit J , Headon Denis J , Akbar Arne N , Mabbott Neil A , Freeman Tom C 
Published: December 2016

AbstractNumerous studies have explored the altered transcriptional landscape associated with skin diseases to understand the nature of these disorders. However, data interpretation represents a significant challenge due to a lack of good maker sets for many of the specialized cell types that make up this tissue, whose composition may fundamentally alter during disease. Here we have sought to derive expression signatures that define the various cell types and structures that make up human skin, and demonstrate how they can be used to aid the interpretation of transcriptomic data derived from this organ. Two large normal skin transcriptomic datasets were identified, one RNA‐seq (n = 578), the other microarray (n = 165), quality controlled and subjected separately to network‐based analyses to identify clusters of robustly co‐expressed genes. The biological significance of these clusters was then assigned using a combination of bioinformatics analyses, literature, and expert review. After cross comparison between analyses, 20 gene signatures were defined. These included expression signatures for hair follicles, glands (sebaceous, sweat, apocrine), keratinocytes, melanocytes, endothelia, muscle, adipocytes, immune cells, and a number of pathway systems. Collectively, we have named this resource SkinSig. SkinSig was then used in the analysis of transcriptomic datasets for 18 skin conditions, providing in‐context interpretation of these data. For instance, conventional analysis has shown there to be a decrease in keratinization and fatty metabolism with age; we more accurately define these changes to be due to loss of hair follicles and sebaceous glands. SkinSig also highlighted the over‐/under‐representation of various cell types in skin diseases, reflecting an influx in immune cells in inflammatory disorders and a relative reduction in other cell types. Overall, our analyses demonstrate the value of this new resource in defining the functional profile of skin cell types and appendages, and in improving the interpretation of disease data. © 2016 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.
MicroRNA‐320a and microRNA‐4496 attenuate Helicobacter pylori cytotoxin‐associated gene A (CagA)‐induced cancer‐initiating potential and chemoresistance by targeting β‐catenin and ATP‐binding cassette, subfamily G, member 2
Authors: Kang Dong Woo , Yang Eun Sun , Noh Yu Na , Hwang Won Chan , Jo Se‐Young , Suh Young‐Ah , Park Won Sang , Choi Kang‐Yell , Min Do Sik 
Published: December 2016

AbstractInfection with Helicobacter pylori is closely linked to an increased risk of gastric cancer. Although cytotoxin‐associated gene A (CagA), a major virulence factor of H. pylori, is known to be a causal factor for gastric carcinogenesis, the molecular link between CagA and gastric cancer‐initiating cell (CIC)‐like properties remains elusive. Here, we demonstrate that CagA is required for increased expression of β‐catenin and its target CIC markers via downregulation of microRNA (miR)‐320a and miR‐4496. CagA promoted gastric CIC properties and was responsible for chemoresistance. miR‐320a and miR‐4496 attenuated the in vitro self‐renewal and tumour‐initiating capacity of CagA‐expressing CICs by targeting β‐catenin. Moreover, miR‐320a and miR‐4496 decreased CagA‐induced chemoresistance by targeting ATP‐binding cassette, subfamily G, member 2 (ABCG2) at the transcriptional and post‐transcriptional levels, respectively. Combination therapy with 5‐fluorouracil and miR‐320a/miR‐4496 suppressed gastric tumourigenesis and metastatic potential in an orthotopic mouse model, probably via suppression of CagA‐induced CIC properties and chemoresistance. Our results provide novel evidence that CIC properties, chemoresistance and tumourigenesis associated with H. pylori are linked to CagA‐induced upregulation of β‐catenin and ABCG2. These data provide novel insights into the molecular mechanisms of CagA‐induced carcinogenisis and the therapeutic potential of of miR‐320a and miR‐4496. Copyright © 2016 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Exploring β‐Tubulin Inhibitors from Plant Origin using Computational Approach
Authors: Verma Kanika , Kannan Kaavya , V Shanthi , R Sethumadhavan , V Karthick , K Ramanathan 
Published: December 2016

AbstractIntroductionβ‐Tubulin is an important target for the binding of anti‐cancer drugs, in particular, paclitaxel (taxol), vinblastine and epothilone. However, mutations in β‐tubulin structure give resistance to chemotherapeutic agents. Notably, mutations at R306C, F270 V, L217R, L228F, A185T and A248V positions in β‐tubulin give high resistance for paclitaxel binding.ObjectiveTo discover novel inhibitors of β‐tubulin from natural sources, particularly alkaloids, using a virtual screening approach.MethodologyA virtual screening approach was employed to find potent lead molecules from the Naturally‐occurring Plant‐based Anti‐cancer Compound‐activity Target (NPACT) database. Alkaloids have great potential to be anti‐cancer agents. Therefore, we have screened all alkaloids from a total of 1574 molecules from the NPACT database for our study. Initially, Molinspiration and DataWarrior programs were utilised to calculate pharmacokinetics and toxicity risks of the alkaloids, respectively. Subsequently, AutoDock algorithm was employed to understand the binding efficiency of alkaloids against β‐tubulin. The binding affinity of the docked complex was confirmed by means of an intermolecular interaction study. Moreover, oral toxicity was predicted by using ProTox program. Further, metabolising capacity of drugs was studied by using SmartCYP software. Additionally, scaffold analysis was done with the help of scaffold trees and dendrograms, providing knowledge about the building blocks for parent‐compound synthesis.ResultsOverall, the results of our computational analysis indicate that isostrychnine, obtained from Strychnosnux‐vomica, satisfies pharmacokinetic and bioavailability properties, binds efficiently with β‐tubulin. Thus, it could be a promising lead for the treatment of paclitaxel resistant cancer types.ConclusionThis is the first observation of inhibitory activity of isostrychnine against β‐tubulin and warrants further experimental investigation. Copyright © 2016 John Wiley & Sons, Ltd.
The REACH Impact on Gun Propellant Formulations
Authors: Böhnlein‐Mauß Jutta , Kröber Hartmut 
Published: December 2016

AbstractREACH is the abbreviation for Registration, Evaluation, Authorisation, and Restriction of Chemicals. It is a regulation of the European Union, adopted to improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemicals industry. Current gun propellant formulations employ environmentally unfriendly materials, like dibutyl‐phthalate (DBP). In this contribution a study was conducted, which aims to evaluate the environmental friendliness of common gun propellant ingredients and to propose environmentally acceptable substitutes for harmful substances. In the first step a simplified assessment matrix based on the REACH relevant properties of chemicals was developed. The matrix consists of the main criteria of the new European regulation, their legal limit values, and their evaluation by REACH. For a selected number of ingredients of commonly used gun propellants the toxicological and eco‐toxicological data were collected in order to carry out an initial assessment under the REACH regulation. In this context some substances show remarkable and critical properties and it was started to find suitable substitutes, which were first assessed with regard to the REACH regulation. As an example potential substitutes for nitroglycerine were experimentally introduced in gun propellant formulations and their main properties were determined and compared with the standard formulation.
Insight into the da Vinci® Xi – technical notes for single‐docking left‐sided colorectal procedures
Authors: Ngu James Chi‐Yong , Sim Sarah , Yusof Sulaiman , Ng Chee‐Yung , Wong Andrew Siang‐Yih 
Published: December 2016

AbstractBackgroundThe adoption of robot‐assisted laparoscopic colorectal surgery has been hampered by issues with docking, operative duration, technical difficulties in multi‐quadrant access, and cost. The da Vinci® Xi has been designed to overcome some of these limitations. We describe our experience with the system and offer technical insights to its application in left‐sided colorectal procedures.MethodsOur initial series of left‐sided robotic colorectal procedures was evaluated. Patient demographics and operative outcomes were recorded prospectively using a predefined database.ResultsBetween March 2015 and April 2016, 54 cases of robot‐assisted laparoscopic left‐sided colorectal procedures were successfully completed with no cases of conversion. The majority were low anterior resections for colorectal malignancies. Using the da Vinci® Xi Surgical System, multi‐quadrant surgery involving dissection from the splenic flexure to the pelvis was possible without redocking.ConclusionsThe da Vinci® Xi simplifies the docking procedure and makes single‐docking feasible for multi‐quadrant left‐sided colorectal procedures.
Iterative learning control design with high‐order internal model for discrete‐time nonlinear systems
Authors: Zhou Wei , Yu Miao , Liu Baobin 
Published: December 2016

SummaryIn this paper, a high‐order internal model (HOIM)‐based iterative learning control (ILC) scheme is proposed for discrete‐time nonlinear systems to tackle the tracking problem under iteration‐varying desired trajectories. By incorporating the HOIM that is utilized to describe the variation of desired trajectories in the iteration domain into the ILC design, it is shown that the system output can converge to the desired trajectory along the iteration axis within arbitrarily small error. Furthermore, the learning property in the presence of state disturbances and output noise is discussed under HOIM‐based ILC with an integrator in the iteration axis. Two simulation examples are given to demonstrate the effectiveness of the proposed control method. Copyright © 2016 John Wiley & Sons, Ltd.