bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time to Definitive Failure to the First Tyrosine Kinase Inhibitor in Localized GI Stromal Tumors Treated With Imatinib As an Adjuvant: A European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group Intergroup Randomized Trial in Collaboration With the Australasian Gastro-Intestinal Trials Group, UNICANCER, French Sarcoma Group, Italian Sarcoma Group, and Spanish Group for Research on Sarcomas
Authors: Casali Paolo G. , Le Cesne Axel , Poveda Velasco Andres , Kotasek Dusan , Rutkowski Piotr , Hohenberger Peter , Fumagalli Elena , Judson Ian R. , Italiano Antoine , Gelderblom Hans , Adenis Antoine , Hartmann Jörg T. , Duffaud Florence , Goldstein David , Broto Javier M. , Gronchi Alessandro , Dei Tos Angelo P. , Marréaud Sandrine , van der Graaf Winette T.A. , Zalcberg John R. , Litière Saskia , Blay Jean-Yves 
Published: November 2015

Purpose In 2004, we started an intergroup randomized trial of adjuvant imatinib versus no further therapy after R0-R1 surgery patients with localized, high- or intermediate-risk GI stromal tumor (GIST). Patients and Methods Patients were randomly assigned to 2 years of imatinib 400 mg daily or no further therapy after surgery. The primary end point was overall survival; relapse-free survival (RFS), relapse-free interval, and toxicity were secondary end points. In 2009, given the concurrent improvement in prognosis of patients with advanced GIST, we changed the primary end point to imatinib failure–free survival (IFFS), with agreement of the independent data monitoring committee. We report on a planned interim analysis. Results A total of 908 patients were randomly assigned between December 2004 and October 2008: 454 to imatinib and 454 to observation. Of these, 835 patients were eligible. With a median follow-up of 4.7 years, 5-year IFFS was 87% in the imatinib arm versus 84% in the control arm (hazard ratio, 0.79; 98.5% CI, 0.50 to 1.25; P = .21); RFS was 84% versus 66% at 3 years and 69% versus 63% at 5 years (log-rank P < .001); and 5-year overall survival was 100% versus 99%, respectively. Among 528 patients with high-risk GIST by local pathologist, 5-year IFFS was 79% versus 73%; among 336 centrally reviewed high-risk patients, it was 77% versus 73%, respectively. Conclusion This study confirms that adjuvant imatinib has an overt impact on RFS. No significant difference in IFFS was observed, although in the high-risk subgroup there was a trend in favor of the adjuvant arm. IFFS was conceived as a potential end point in the adjuvant setting because it is sensitive to secondary resistance, which is the main adverse prognostic factor in patients with advanced GIST.
Radiation Dose-Response Relationship for Risk of Coronary Heart Disease in Survivors of Hodgkin Lymphoma
Authors: van Nimwegen Frederika A. , Schaapveld Michael , Cutter David J. , Janus Cècile P.M. , Krol Augustinus D.G. , Hauptmann Michael , Kooijman Karen , Roesink Judith , van der Maazen Richard , Darby Sarah C. , Aleman Berthe M.P. , van Leeuwen Flora E. 
Published: November 2015

Purpose Cardiovascular diseases are increasingly recognized as late effects of Hodgkin lymphoma (HL) treatment. The purpose of this study was to identify the risk factors for coronary heart disease (CHD) and to quantify the effects of radiation dose to the heart, chemotherapy, and other cardiovascular risk factors. Patients and Methods We conducted a nested case-control study in a cohort of 2,617 5-year HL survivors, treated between 1965 and 1995. Cases were patients diagnosed with CHD as their first cardiovascular event after HL. Detailed treatment information was collected from medical records of 325 cases and 1,204 matched controls. Radiation charts and simulation radiographs were used to estimate in-field heart volume and mean heart dose (MHD). A risk factor questionnaire was sent to patients still alive. Results The median interval between HL and CHD was 19.0 years. Risk of CHD increased linearly with increasing MHD (excess relative risk [ERR]) per Gray, 7.4%; 95% CI, 3.3% to 14.8%). This results in a 2.5-fold increased risk of CHD for patients receiving a MHD of 20 Gy from mediastinal radiotherapy, compared with patients not treated with mediastinal radiotherapy. ERRs seemed to decrease with each tertile of age at treatment (ERR/Gy<27.5years, 20.0%; ERR/Gy27.5-36.4years, 8.8%; ERR/Gy36.5-50.9years, 4.2%; Pinteraction = .149). Having ≥ 1 classic CHD risk factor (diabetes mellitus, hypertension, or hypercholesterolemia) independently increased CHD risk (rate ratio, 1.5; 95% CI, 1.1 to 2.1). A high level of physical activity was associated with decreased CHD risk (rate ratio, 0.5; 95% CI, 0.3 to 0.8). Conclusion The linear radiation dose-response relationship identified can be used to predict CHD risk for future HL patients and survivors. Appropriate early management of CHD risk factors and stimulation of physical activity may reduce CHD risk in HL survivors.
Distribution of Voltage Induced by Magnetic Field of Parallel Transmission Line Along Dead and Grounded Lines
Authors: Токарский  , Tokarskiy A. , Рубцова  , Rubtsova Nina 
Published: November 2015

With the view of calculation methods accuracy increase duringcalculations by Carson’s method, by simplified Carson’s
method and by hequ method, we considered induced voltage parameters,currents and voltage distribution alonggrounded
on the ends single-wire transmission lines created by magnetic field of parallel single-wire operating line. It is shown that
hequ method, eliminating errors in the &#34;dead zone&#34; in calculation by Carson’s method, gives almost identical results outside
the &#34;dead zone&#34;, and small differences with the results of simplified Carson’s method.
Exploring Contextual Factors of Youth Homelessness And Sexual Risk Behaviors: A Qualitative Study
Authors: Santa Maria Diane , Narendorf Sarah C. , Ha Yoonsook , Bezette‐Flores Noel 
Published: November 2015

AbstractCONTEXTHIV disproportionately affects homeless youth, and interventions to date have had minimal success in reducing sexual risk behaviors in this population. Few qualitative studies have been conducted to provide insight into the influence of homelessness‐related factors on sexual risk behaviors.METHODSA qualitative study with a quantitative component was conducted with a nonprobability sample of 64 homeless youth aged 14–24; participants were recruited from a variety of venues in Houston between October 2013 and March 2014. Thirteen focus group discussions were conducted; thematic analysis was used to identify themes related to HIV risk.RESULTSParticipants were predominantly black (75%), sheltered (67%) and aged 18 or older (77%). Youth discussed how the circumstances of their homelessness and the struggle to meet their immediate needs led to behaviors and experiences that put them at risk for HIV. Three themes emerged: Homeless youth frequently engage in risky sexual behavior, sometimes as a way to cope with stress; they often trade sex, either voluntarily or involuntarily, for such necessities as money or a place to sleep; and many experienced childhood sexual victimization or have been victimized since becoming homeless. Youth also described how stress, stigma and self‐reliance contributed to their involvement in HIV risk behaviors.CONCLUSIONSHIV prevention methods that target stress and stigma while respecting youths’ self‐reliance may help reduce sexual risk behaviors. Further research is needed to determine suitable behavioral change techniques to address these potentially modifiable factors.
Numerical Computation of the Inverse Born Approximation
for the Nonlinear Schrödinger Equation in Two Dimensions
Authors: Harju Markus 
Published: November 2015

Abstract
This work
deals with the numerical computation of the inverse Born approximation associated with inverse scattering problems for the nonlinear Schrödinger equation in two space dimensions. We consider both backscattering and fixed angle data. The problem of computing the Born approximation is formulated as a linear inverse problem which is solved using a regularization method. Numerical examples with noisy data are given to illustrate the effectiveness of this method.
Successful external cephalic version after preterm premature rupture of membranes utilizing amnioinfusion complicated by fetal femoral fracture
Authors: Stanhope Todd J. , Nassr Ahmed A. , Boldt Kristi L. , El-Nashar Sherif A. , Brost Brian C. 
Published: November 2015

Abstract
We report a case of successful external cephalic version after preterm premature rupture of membranes. Transcervical amnioinfusion was used to facilitate the procedure due to minimal amniotic fluid, and the patient subsequently delivered vaginally. A femoral fracture was later identified in the neonate.
The Transformation of Medicare, 2015 to 2030
Authors: Aaron Henry J. , Reischauer Robert 
Published: November 2015

Abstract
Medicare today is a better program on almost every dimension than it was just after July 30, 1965 when Lyndon Johnson signed public law 89–97. Nonetheless, short-comings, limitations, and inadequacies remain. What should be done to make Medicare a better program? What should Medicare look like in 2030? In this paper we try to answer these questions. Three perspectives are relevant: that of beneficiaries, current and future; that of policymakers and administrators, the program’s stewards; and that of society at large. We posit certain objectives and goals that we believe – and that we think a broad swath of Americans would agree – should be pursued to improve the Medicare program. Those goals include (a) affordability for Medicare beneficiaries, (b) affordability for the working population that is paying and should continue to pay for much of the current cost of the program, (c) reduction in what we regard as needless complexity, and (d) stability and continuity in several different senses. We restrict ourselves to changes that we judge to be affordable and feasible – politically, technically, and administratively – if not today, then over the next decade or two. We believe that changes in Medicare will remain incremental, as they have been for the last 50 years. We shall assume that the ACA takes root and that the exchanges, whether managed by states or by the federal government on behalf of the states, continue to operate. We shall assume that federal and state officials eventually surmount the administrative challenges they still confront. In particular, we assume that the exchanges come to serve a growing share of the American population and that they increasingly exercise the rather considerable regulatory powers over insurance offerings that the ACA grants to them. We divide Medicare reforms into four categories: payment reform, benefit reform, quality reform and management, and the role of private insurance plans (Medicare Advantage [MA]).
Fatigue behavior of wood-fiber-based tri-axial engineered sandwich composite panels (ESCP)
Authors: Li Jinghao , Hunt John F. , Gong Shaoqin , Cai Zhiyong 
Published: November 2015

Abstract
The static and fatigue bending behavior of wood-fiber-based tri-axial engineered sandwich composite panels (ESCP) has been investigated by four-point bending tests. Fatigue panels and weakened panels (wESCP) with an initial interface defect were manufactured for the fatigue tests. Stress σ vs. number of cycles curves (S-N) were recorded under the different stress levels. The primary failure mode in the fatigue tests was observed in the shear zone (epoxy debonding), which was different from face failure in the pure bending zone for the static bending test. For residual bending (RB) test, epoxy debonding failure occurred between the pure bending zone and shear zone. Macro cracks along the core/face interface developed as the number of cycles increased during the fatigue life. The crack propagation or damage for the panels submitted to fatigue test can be described as a three-stage damage process of first non-linear portion, followed by linear damage accumulation, and lastly non-linear accelerated damage. Bending stiffness degradation at the higher load level had faster degradation during fatigue life. The dissipated energy of the panels was small due to the high stiffness of the materials.
Comparative effectiveness and safety of 3D versus 2D endoscopy in skull base surgery: a systematic review
Authors: Marcus Hani J. , Wan Yizhou , Ulrich Nils H. , Reisch Robert 
Published: November 2015

Abstract

Background: The recent introduction of 3-dimensional (3D) endoscopes may improve depth perception, but this must be balanced against their higher cost, larger size, and greater weight.

Methods: The Cochrane Central Register of Controlled Trials (CENTRAL) and PubMed databases were searched between January 1990 and December 2014. Titles and abstracts were screened to identify publications that (1) featured adult patients, (2) compared 2D and 3D endoscopy, and (3) reported on effectiveness or safety.

Results: A total of 163 articles were pooled from the electronic databases. After exclusion, six articles were identified that satisfied the inclusion criteria, comprising three preclinical studies, two retrospective cohort studies, and one case-control study. In the clinical studies a total of 244 patients undergoing endoscopic pituitary surgery were reported – 140 (57.4%) with 2D HD endoscopes, and 104 (42.6%) with 3D SD endoscopes. There was no significant difference in the extent of resection, operating time, or complications, between the 2D and 3D groups.

Conclusion: Larger prospective clinical studies comparing 3D and 2D are warranted to determine the extent to which subjective improvements in perception lead to objective improvements in patient outcome.
Stable gradient projection method for nonlinear conditionally well-posed inverse problems
Authors: Kokurin Mikhali Y. 
Published: November 2015

Abstract
We study the standard gradient projection method in a Hilbert space, as applied to minimization of the residual functional for nonlinear operator equations with differentiable operators. The functional is minimized over a closed, convex and bounded set, which contains a solution to the equation. It is assumed that the inverse problem associated with the operator equation is conditionally well-posed with a Hölder-type modulus of relative continuity. We prove that the iterative process is asymptotically stable with respect to errors in the right part of the operator equation. Moreover, the process delivers in the limit an order optimal approximation to the desired solution.
Fast Toeplitz linear system inversion for solving two-dimensional acoustic inverse problem
Authors: Kabanikhin Sergey I. , Novikov Nikita S. , Oseledets Ivan V. , Shishlenin Maxim A. 
Published: November 2015

Abstract
The coefficient inverse problem for the acoustic equation is considered. We propose the method for reconstructing the density based on the N-approximation by the finite system of one-dimensional problems and the two-dimensional M. G. Krein approach. The two-dimensional analogue of the M. G. Krein approach is applied to reduce the non-linear inverse problem to a family of linear integral equations. We consider the fast algorithm for solving the relevant linear system, based on using the block-Toeplitz structure of the matrix. The algorithm applied to the M. G. Krein equation allows to obtain the solution of the whole family of the integral equations by solving only one linear system. Results of numerical calculations are presented.
Ein einfaches Verfahren zur Schätzung von Referenzintervallen aus routinemäßig erhobenen Labordaten
Authors: Hoffmann Georg , Lichtinghagen Ralf , Wosniok Werner 
Published: November 2015

Zusammenfassung
Nach Empfehlungen der IFCC und anderer Organisationen sollen medizinische Laboratorien alle Referenzintervalle selbst erheben oder zumindest individuell anpassen, um Besonderheiten der jeweiligen Methoden und Patientenkollektive abzubilden. In der Praxis ist diese Forderung allerdings nur schwer umzusetzen. Deshalb erarbeiten zwei DGKL-Arbeitsgruppen („AG Richtwerte“ und „AG Bioinformatik“) Methoden zur Schätzung von Referenzintervallen aus routinemäßig erhobenen Labordaten. In der vorliegenden Arbeit beschreiben wir ein visuelles Verfahren, das direkt auf einem Excel-Blatt ohne Programmierkenntnisse durchgeführt werden kann. Die Patientenwerte werden dafür in einem Punktediagramm gegen Quantile der Standardnormalverteilung aufgetragen (sog. QQ-Plot unter Verwendung der NORM.INV-Funktion von Excel). Falls die untersuchte Population vorwiegend nicht-kranke Personen mit annähernd normalverteilten Werten enthält, bilden deren Punkte eine Gerade. Häufig sind die Werte eher lognormalverteilt; dann erkennt man die Gerade nach Logarithmierung der Originalwerte. Werte, die nicht zur angenommenen theoretischen Verteilung passen, sind in dieser Darstellung durch eine Abweichung von der Geradenform gut erkennbar und können eliminiert werden. Aus den bereinigten Werten werden dann Mittelwert und Standardabweichung berechnet, um das Referenzintervall (μ±2σ) zu schätzen. Die Methode liefert mit simulierten Werten und Echtdaten plausible Ergebnisse. Mit steigendem Anteil von Werten, die nicht zum Modell passen, tendiert das Verfahren zur Unterschätzung der Standardabweichung. In allen Fällen, in denen der QQ-Plot keine eindeutige Gerade liefert, ist das vorgeschlagene Verfahren nicht anwendbar.
The affective tone of narration and posttraumatic growth in organ transplant recipients
Authors: Zięba Mariusz , Zatorski Mateusz , Boczkowska Marta , Gozdowska Jolanta , Kieszek Rafał , Laskowski Wojciech 
Published: November 2015

Abstract
The aim of the study was to verify the hypothesis that positive affective tone of narratives is connected to the experience of posttraumatic growth among transplant patients. Kidney transplant patients (N = 51) and liver transplant patients (N = 48) participated in the study. In the first stage, about 10 weeks after transplant, the participants told two stories about important, freely chosen events from their lives. During the second meeting 10-12 months later we measured posttraumatic growth. Results indicated that the affective tone of narratives about past events was associated with the level of post-traumatic growth measured 10-12 months later. This proves that the affective tone of narratives about life, understood as a relatively constant individual characteristic, promote posttraumatic growth.
Dream emotionality. Selected formal properties of dreams
Authors: Grzywacz Kinga 
Published: November 2015

Abstract
The aim of the study was to verify hypotheses about time changeability of dream characteristics depending on the participants’ age and affective value of the dream. The study was conducted online. Participants of the study were 68 individuals between the age of 17 and 85. The participants were asked to prepare detailed descriptions of their dreams, next they had to identify elements of the dreams, refer them to their real life, and assess their affective value. In the dreams of late adolescents, and young and middle-aged adults the most frequently recalled period in a positive context turned out to be late adolescence and early adulthood, whereas in a negative context the participants would recall their present developmental phase and the period of late childhood. Unpleasant dreams of older individuals were mainly connected with the period of middle adulthood, whereas those pleasant ones referred to various periods of their entire life.
Is your mood more contagious if you are likeable? The role of liking in the social induction of affect
Authors: Wróbel Monika , Królewiak Klara 
Published: November 2015

Abstract
In the present study, we explored the role of liking in the social induction of affect. Dispositional likeability was manipulated by written reports describing a sender as a likeable or dislikeable character. Afterwards participants watched short videos presenting the sender displaying happy or sad emotional expressions. We expected that exposure to the likeable sender would lead to reactions concordant with his emotional expression (assimilation), whereas exposure to the dislikeable sender would result in discordant reactions (contrast). The results indicated that dispositional likeability influenced the social induction of affect when the sender expressed positive emotions. Moreover, liking mediated the effects of the happy sender’s dispositional likeability on participants’ affective state. Exposure to the sad sender, however, led to assimilation regardless of the sender’s dispositional likeability.
Design and analysis of a complementary split ring resonator (CSRR) metamaterial based antenna for wideband application
Authors: Islam Sikder Sunbeam , Alam Touhidul , Iqbal Faruque Mohammad Rashed , Islam Mohammad Tariqul 
Published: November 2015

AbstractIn this article, a compact complementary split ring resonator (CSRR) based double-negative (DNG) metamaterial antenna is presented for wideband (4.49 GHz–21.85 GHz) wireless application. The antenna is incorporated with a DNG metamaterial patch: 50Ω microstrip feed line and partial ground plane. The antenna shows measured fractional bandwidth of 131.81% with a compact size of 0.37λ×0.37λ×0.01λ. The commercially available finite integration technique (FIT)-based simulation software, computer simulation technology (CST) microwave studio was adopted to investigate the performance of the proposed antenna. Several parametric studies were performed to investigate the effect of key structural parameters on antenna performances. The double-negative characteristics of the metamaterial were investigated as well.
Pile Model Tests Using Strain Gauge Technology
Authors: Krasiński Adam , Kusio Tomasz 
Published: November 2015

Abstract
Ordinary pile bearing capacity tests are usually carried out to determine the relationship between load and displacement of pile head. The measurement system required in such tests consists of force transducer and three or four displacement gauges. The whole system is installed at the pile head above the ground level. This approach, however, does not give us complete information about the pile-soil interaction. We can only determine the total bearing capacity of the pile, without the knowledge of its distribution into the shaft and base resistances. Much more information can be obtained by carrying out a test of instrumented pile equipped with a system for measuring the distribution of axial force along its core. In the case of pile model tests the use of such measurement is difficult due to small scale of the model.
To find a suitable solution for axial force measurement, which could be applied to small scale model piles, we had to take into account the following requirements:
- a linear and stable relationship between measured and physical values,
- the force measurement accuracy of about 0.1 kN,
- the range of measured forces up to 30 kN,
- resistance of measuring gauges against aggressive counteraction of concrete mortar and against moisture,
- insensitivity to pile bending,
- economical factor.
These requirements can be fulfilled by strain gauge sensors if an appropriate methodology is used for test preparation (Hoffmann [1]). In this paper, we focus on some aspects of the application of strain gauge sensors for model pile tests. The efficiency of the method is proved on the examples of static load tests carried out on SDP model piles acting as single piles and in a group.