bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bathroom adaptation to meet the expectations of the client suffering from Multiple Sclerosis (MS) as an example of occupational therapy process
Authors: Derbich Jolanta 
Published: June 2017

Abstract
Introduction: Multiple sclerosis is a disease attacking the central nervous system. It develops when the myelin sheaths of nerve fibres, glial cells and immune cells are damaged [3]. The aim of this study was to present the project of adapting a bathroom to the needs and expectations of a person with MS and to show its implementation.
Method: A direct interview with an MS client was conducted with COPM questionnaire (often used in occupational therapy) and medical documentation was analysed.
Case study: Tadeusz (the client) was a 46-year-old man. He was diagnosed with MS when he was 43 years old. However, the first symptoms occurred two years earlier. In 2007 he underwent magnetic resonance and spine puncture examinations. The results confirmed a primary progressive type of MS. Identification of the client’s problem: the need of independence while washing, shaving and bathing. Tadeusz was not able to take a shower by himself because of the fear of losing balance and falling down in the bathroom. The weakness of the left hand muscles and the lack of support rails made it impossible to use the bathroom independently. During several meetings with the client, a plan of adapting his bathroom (fixing handrails and a wooden step) was developed and the manner of using these devices was practised.
Conclusions: Two weeks after the bathroom adaptation was finished, it was assessed together with the client. It was concluded that the adaptation meets his expectations and the aim is being gradually achieved. In the reassessment process, an improvement by 3 points was noted. The “task performance” and “satisfaction” criteria were given 7 points (in the scale from 1 to 10) by the client. However, in the first assessment he evaluated these criteria by giving them 4 points each.
The frequency of bone fractures among patients with chronic kidney disease not on dialysis: two-year follow-up
Authors: Figurek Andreja , Vlatkovic Vlastimir , Vojvodic Dragan , Gasic Branislav , Grujicic Milorad 
Published: June 2017

Abstract

Introduction. Renal osteodystrophy is a severe complication of chronic kidney disease (CKD) that increases morbidity and mortality in these patients. Mineral and bone disorder starts early in CKD and affects the incidence of bone fractures. The aim of this study was to observe the frequency of diverse bone fractures in patients with CKD not on dialysis.

Methods. This cohort study included 68 patients that were followed during the two-year period. The patients were divided into two cohorts: one that developed bone fractures and the other that did not. There were 35 (51.5%) men and 33 (48.5%) women. The mean age of patients ranged 62.88±11.60 years. During follow-up serum values of chronic kidney disease – mineral and bone indicators were measured. The methods of descriptive and analytical statistics were used in order to analyze obtained data.

Results. During this two-year follow-up seven patients developed bone fractures. Among them, females dominated (6 patients) compared to males (only 1 patient). The most common were fractures of forearm. The mean level of parathyroid hormone (PTH) at the beginning of the monitoring was higher in the group of patients with bone fractures (165.25 ± 47.69 pg/mL) in regard to another group (103.96 ± 81.55 pg/mL). After two-year follow-up, this difference became statistically significant at the level p < 0.05. Patients that developed bone fractures had higher FRAX (Fracture Risk Assessment) score compared to another group.

Conclusion. In our study, about 10% of patients had bone fractures in the two-year follow-up period. Patients who developed fractures had a higher PTH level and FRAX score.
Does Foreign Ownership Increase Firms’ Productivity? Evidence from Firms Listed on Amman Stock Exchange
Authors: Tayem Ghada 
Published: June 2017

AbstractThe purpose of this paper is to investigate the impact of foreign ownership on the production efficiency of firms listed on the Amman Stock Exchange using hand-collected, firm-level data. Arab countries have been performing poorly in attracting foreign direct investment (FDI) inflows in comparison to other developing countries, and hence, they may be missing out on growth and development opportunities. Jordan, however, has been one of the most successful Arab countries in attracting FDI inflows relative to its economic size. Therefore, Jordan offers an ideal setting to examine the benefits of foreign ownership in the region. However, this study fails to find evidence supporting the notion that foreign ownership enhances production efficiency. This finding calls into question the economic viability of investment incentives designed to attract foreign investors.
Global clotting assays - monitoring the effect of by-passing agents in haemophilia patients with inhibitors
Authors: Șerban Margit , Poenaru Dan , Cernat Laura , Savescu Delia , Pătrașcu Jenel , Schramm Wolfgang , Ursu Emilia , Mihailov Delia , Jinca Cristian , Ioniță Ioana , Arghirescu Smaranda 
Published: June 2017

Abstract
The development of FVIII/FIX inhibitor alloantibodies represents a severe complication requiring specific laboratory evaluation for establishing a life-saving therapy regimen. Our preliminary study aimed at elaborating a laboratory strategy for monitoring the effectiveness of Activated Prothrombin Complex Concentrate (APCC) and recombinant activated factor VII (rFVIIa) in haemophiliacs with inhibitors, by checking the reliability and clinical value of three complementary assays: clotting-time based coagulometry, thrombelastography (TEG) and thrombin generation assay (TGA). The investigations were performed on 7 patients with severe haemophilia A with high titer inhibitors treated for 12 episodes of severe bleedings, 5 of them for surgical interventions. After the administration of bypassing agents (BPAs) the clotting-time based assay brought changes only on prothrombin (p<0.01), potentially signaling a thrombotic risk, without any impact on the global hemostasis. TEG displayed prompt significant improvement only after rFVIIa (90μg/kg). TGA revealed significantly improved values for peak and velocity index, time to peak and start tail after both BPAs. Despite some disparities between biological hemostatic phenotype and clinical response to therapy, we concluded that TEG and TGA are the only current exploratory assays, expressing the quality of haemostatic control, representing a real support for a personalized, adapted therapy in hemophilia with inhibitors.
Therapy-related myelodysplastic syndrome after successful treatment of acute promyelocytic leukemia: case report and literature review
Authors: Cîrstea Mihaela , Coliță Adriana , Ionescu Bogdan , Ghiaur Alexandra , Vasilescu Didona , Dobrea Camelia , Jardan Cerasela , Dragomir Mihaela , Gheorghe Anca , Várady Zsofia , Lupu Anca Roxana 
Published: June 2017

Abstract
In the 2016 revision of the World Health Organization classification the term therapy-related myeloid neoplasia (t-MN) defines a subgroup of acute myeloid leukemia (AML) comprising patients who develop myelodysplastic syndrome (MDS-t) or acute myeloid leukemia (AML-t) after treatment with cytotoxic and/or radiation therapy for various malignancies or autoimmune disorders. We report the case of a 36 year old patient with t-MN (t-MDS) after achieving complete remission (CR) of a PML-RARA positive acute promyelocytic leukemia (APL) at 32 months after diagnosis. Initially classified as low risk APL and treated according to the AIDA protocol - induction and 3 consolidation cycles - the patient achieved a complete molecular response in September 2013 and started maintenance therapy. On follow-up PML-RARA transcript remained negative. In January 2016 leukopenia and thrombocytopenia developed and a peripheral blood smear revealed hypogranular and agranular neutrophils. Immunophenotyping in the bone marrow aspirate identified undifferentiated blast cells that did not express cytoplasmic myeloperoxidase. The cytogenetic study showed normal karyotype. The molecular biology tests not identified PMLRARA transcript. A diagnosis of t-MDS (AREB-2 - WHO 2008) was established. Treatment of AML was started with 2 “3+7” regimens and 1 MEC cycle. Two months from diagnosis, while in CR, an allogeneic HSCT from an unrelated HLA compatible donor was performed after myeloablative regimen. An unfavorable clinical evolution was followed by death on day 9 after transplantation. The occurrence of t-MNs during CR of APL represents a particular problem in terms of follow-up and differential diagnosis of relapse and constitutes a dramatic complication for a disease with a favorable prognosis.
This work was supported by the grants PN 41-087 /PN2-099 from the Romanian Ministry of Research and Technology
Easily Available Blood Test Neutrophil-To-Lymphocyte Ratio Predicts Progression in High-Risk Non-Muscle Invasive Bladder Cancer
Authors: Martha Orsolya , Porav-Hodade Daniel , Bălan Daniel , Tătaru Octavian Sabin , Sin Anca , Chibelean Călin Bogdan , Vartolomei Mihai Dorin 
Published: June 2017

Abstract
Introduction: The inflammatory response surrounding the tumour has a major importance in the oncologic outcome of bladder cancers. One marker proved to be useful and accessible is NLR (neutrophil-to-lymphocyte ratio). The objective of the study was the analysis of NLR as a prognostic factor for recurrence and progression in pT1a and pT1b bladder cancers.
Material and Methods: Retrospective study, with 44 T1a/T1b bladder cancer patients. Each patient underwent transurethral resection. NLR was considered altered if higher than 3, average follow-up period was of 18 months.
Results: The mean age of the patients included was 73 years (IQR 64 - 77). Most of the patients had NLR<3 (30 patients). In total 29/44 (65.9 %) patients presented recurrence and 15/44 (34.1 %) patients were identified with T2 or higher stage progression during the follow-up period (average 18 months).We found no statistically significant association between NLR>3 and other clinic and pathologic factors. Progression-free survival (PFS) Kaplan-Meier analysis showed a lower PFS in the NLR>3 group, with a p=0.001 value. A total of 64.3% of patients had shown progression in the NLR>3 group and 20% in the NLR<3 group. Mean NLR was 2.67 (IQR 1.88-3.5); 2.50 (IQR 1.89-2.87) in patients that did not present any progression during the follow-up and 3.20 (IQR 1.73-5.80) in those with progression (p=0.09), ROC 0.655. Mean NLR was 2.14 (IQR 1.61-2.77) in patients that did not experience a recurrence during the follow-up and 2.76 (IQR 2.1-4.31) in those with recurrence, ROC 0.671 (p=0.06). Multivariable Cox regression analyses showed that stage T1b and NLR represent independent prognostic factors for PFS.
Conclusion: High Neutrophil-to-Lymphocyte ratio retained a statistically significant value, as an independent prognostic factor for bad prognosis of T1 bladder tumors. NLR represents a biomarker that could support a clinical decision making in case of high-risk on-muscle invasive bladder cancer.
The arbre-tree sign: Pictures and words in counterpoint in the Cours de linguistique générale
Authors: Joseph John E. 
Published: June 2017

AbstractIn his three courses of lectures on general linguistics given between 1907 and 1911, Ferdinand de Saussure (1857–1913) sometimes drew diagrams and figures on the chalkboard to add a visual dimension to the novel and challenging theoretical concepts he was laying out. Those which the editors redrew for inclusion in the Cours de linguistique générale (1916) – in some cases with significant changes – have had a surprisingly strong impact on readers ever since. If Saussure hoped that the drawings would clear up ambiguities in his verbal text, he might have been disappointed; for while they extend a hand to students and readers to guide them into his conceptual world via the stepping-stones of the semi-familiar, accessible and concrete, they have opened up whole new realms of ambiguity, and strengthened the ones already present in the verbal text. This article examines seven of the illustrations or sets of illustrations in the CLG and the various interpretations to which they have given or could give rise, treating these not as erroneous but as contrapuntal to the text when the two appear to be in contradiction.
Adaptability, stability, productivity and genetic parameters in slash pine second-generation families in early age
Authors: Pagliarini M.K. , Kieras W.S. , Moreira J.P. , Sousa V.A. , Shimizu J.Y. , Moraes M.L.T. , Furlani E. , Aguiar A.V. 
Published: June 2017

AbstractThe study was conducted to estimate the stability, adaptability, productivity and genetic parameters in Slash pine second-generation half-sib families, considering phenotypic traits in early age. Forty-four families from a first generation seed orchard in Colombo-PR, Brazil, were used in this study. Two progenies tests were established in a randomized complete block design. The first test was implemented in March 2009 in Ribeirão Branco, São Paulo state, containing 40 blocks, one tree per plot, 44 treatments (progenies) and 6 controls. Another test was implemented in Ponta Grossa, Paraná state, using the same experimental design and number of plants per plot, and with 24 treatments, 32 blocks. The growth traits evaluated were total height, diameter at breast height (dbh) and wood volume, within five years. The form traits evaluated were stem form, branch thickness, branch angle, number of branches, fork and fox tail five years after planting. Deviance analysis and estimates of stability, adaptability, productivity and genetic parameters were performed using the methods of best linear unbiased predictor (BLUP) and residual maximum likelihood (REML). There was significant variation among progenies for growth and form traits. Considerable genetic variation was detected mainly for wood volume. High coefficients of genetic variation and heritability showed low environmental influence on phenotypic variation, which is important for the prediction of genetic gain by selection. Crosses between different progenies individuals groups will be prioritized for obtaining heterotics genotypes and increase the probability of obtaining high specific combining ability.
Numerical Approach in Recognition of Selected Features of Rock Structure from Hybrid Hydrocarbon Reservoir Samples Based on Microtomography
Authors: Kaczmarek Łukasz Dominik , Zhao Yufeng , Konietzky Heinz , Wejrzanowski Tomasz , Maksimczuk Michał 
Published: June 2017

Abstract
The study employs numerical calculations in the characterization of reservoir sandstone samples based on high-resolution X-ray computed microtomography. The major goals were to determine porosity through pore size distribution, permeability characterization through pressure field, and structure impact on rock strength by simulation of a uniaxial compression test. Two Miocene samples were taken from well S-3, located in the eastern part of the Carpathian Foredeep. Due to the relation between sample size and image resolution, two X-ray irradiation series with two different sample sizes were performed. In the first approach, the voxel side was 27 μm and in the second it was up to 2 μm. Two samples from different depths have been studied here. Sample 1 has petrophysical features of conventional reservoir deposits, in contrast to sample 2. The approximate grain size of sample 1 is in the range 0.1-1.0 mm, whereas for sample 2 it is 0.01-0.1 mm with clear sedimentation lamination and heterogenic structure. The porosity, as determined by μCT, of sample 1 is twice (10.3%) that of sample 2 (5.3%). The equivalent diameter of a majority of pores is less than 0.027 mm and their pore size distribution is unimodal right-hand asymmetrical in the case of both samples. In relation to numerical permeability tests, the flow paths are in the few privileged directions where the pressure is uniformly decreasing. Nevertheless, there are visible connections in sample 1, as is confirmed by the homogenous distribution of particles in the pore space of the sample and demonstrated in the particle flow simulations. The estimated permeability of the first sample is approximately four times higher than that of the second one. The uniaxial compression test demonstrated the huge impact of even minimal heterogeneity of samples in terms of micropores: 4-5 times loss of strength compared to the undisturbed sample. The procedure presented shows the promising combination of microstructural analysis and numerical simulations. More specific calculations of lab tests with analysis of variable boundary conditions should be performed in the future.
The Impact of the Low Throw Fault on the Stability of Roadways in a Hard Coal Mine
Authors: Małkowski Piotr , Ostrowski Łukasz , Bachanek Piotr 
Published: June 2017

AbstractEnsuring roadways stability in hard coal mines is one of the main challenges faced by engineers. A changeable geological structure have caused the roadway’s conditions to vary, thus influencing its stability. One of the causes of those changes is the presence of a previously undiscovered fault zone (small faults crossed the roadway) within which a significant convergence or support deformation may occur.The paper presents the impact of low throw faults on the degree of convergence of roadways. Convergence is determined for two roadways in the hard coal mine. A special measuring stations have been installed in one of the roadways, and they have carried out constant measurements for 15 months. In the other roadway, the degree of convergence has been determined on the basis of an on-site verification and comparison of the measurements obtained and the initial values, based on the roadway’s records.On the basis of the obtained convergence results, the impact of a single fault and the entire fault zone on the roadway stability has been determined. The impact of a single, low throw fault results in a 30% higher vertical convergence than in the case of roadways free of geological disturbance. In the roadway section located in the fault zone, vertical convergence is 4 times higher than in the case of sections free of disturbance impact. The floor heaving constitutes ca. 90% of vertical convergence both for roadway sections situated within the faulted zones and for sections free of the influence of any additional factors.
The Semantics and Pragmatics of the Conditional in al-Fārābī’s and Avicenna’s Theories
Authors: Chatti Saloua 
Published: June 2017

Abstract
In this paper, I examine al-Fārābī's and Avicenna's conceptions of the conditional. I show that there are significant differences between the two frames, despite their closeness. Al-Fārābī distinguishes between an accidental conditional and two “essential” conditionals. The accidental conditional can occur only once and pragmatically involves succession. In the first “essential” conditional, the consequent follows regularly the antecedent; pragmatically it involves likeliness. The second “essential” conditional can be either complete or incomplete. Semantically the former means “if and only if”; pragmatically it means “necessarily if and only if”. The latter is expressed by ‘if, then’ and means entailment; pragmatically, it involves necessity and the inclusion of the antecedent into the consequent. As to Avicenna, he rejects explicitly al-Fārābī’s complete conditional and distinguishes between the luzūm (real implication) and what he calls ittifāq. He quantifies over situations (or times) to express the various conditionals. The two universals A
C and E
C are expressed by “In all situations, if…, then…”, while the two particulars I
C and O
C are expressed by “In some situations, if…, then..”. This gives them a modal connotation, and makes the universals close to strict implications. Pragmatically, A
C presupposes the truth of the antecedent, but there is no such presupposition in E
C, while what is presupposed in both I
C and O
C is a (possible) conjunction.
Despite these differences, in both systems, the conditional is not truth functional, unlike the Stoic conditional.
Assertions and Conditionals: A Historical and Pragmatic Stance
Authors: Chiffi Daniele , Di Giorgio Alfredo 
Published: June 2017

Abstract
The assertion candidate expresses a potential logical-linguistic object that can be asserted. It differs from both the act and the product of assertion; it needs not to be actually asserted and differs from the assertion made. We investigate the medieval origins of this notion, which are almost neglected in contemporary logic. Our historical analysis suggests an interpretation of the assertion candidate within the system of logic for pragmatics.
Common wintering of black kites (Milvus migrans migrans) in Greece, and new data on their wintering elsewhere in Europe
Authors: Literák Ivan , Horal David , Alivizatos Haralambos , Matušík Hynek 
Published: June 2017

Abstract
Black kites of the nominal subspecies Milvus migrans migrans breed in the Western Palearctic and in Central Asia, while the European population is relatively small. The birds winter mostly in sub-Saharan Africa. Until 2000 winter observations of black kites were rare in Greece, and also within the tri-point border area of Austria, the Czech Republic and Slovakia. At that time regular wintering of black kites started there. These data and evidence from recent local literature as well as from a number of unpublished data obtained throughout European countries and reviewed in this paper corroborate the impression that numbers of black kites wintering in Europe and the whole Mediterranean area including Turkey are increasing. The reasons considered are climate warming in the area and some negative changes in sub-Saharan Africa in the traditional wintering grounds of black kites. Notes about the wintering of black/red kite hybrids are also added.
Combined Flow Control of Positively Bowed Blade and Vortex Generator Jet on a Compressor Cascade
Authors: Li Longting , Song Yanping , Chen Fu 
Published: June 2017

Abstract
A combined flow control method based on positively bowed blade and endwall vortex generator jet (VGJ) was performed to a compressor cascade under three kinds of inlet conditions. The results show that the endwall VGJ can further decrease the total losses in positively bowed cascades. At 0° incidence with zero inlet boundary layer, the separation type in the positively bowed blade is open, with the VGJ, the loss reduction is 2.7 %. As the inlet boundary layer thickens at 0° incidence, the separation region increases with the separation type keeping unchanged, the loss reduction increasing to 11.73 %. As the incidence rises to +7° with zero inlet boundary layer, the separation type converts into closed and the flow separation is the severest in the three cases, with the VGJ, however, the loss reduction is just 7.4 %, which means that the control effect of endwall VGJ not only depends on the size of separation region but also relies on the type of separation mode. If the separation type is open, as the size of separation region expands, the control effectiveness of endwall VGJ increases; if the separation type converts into closed with the further aggravation of flow field, that control effect will decrease.