bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arginine and proline applied as food additives stimulate high freeze tolerance in larvae of Drosophila melanogaster
Authors: Koštál Vladimír , Korbelová Jaroslava , Poupardin Rodolphe , Moos Martin , Šimek Petr 
Published: August 2016

ABSTRACT
The fruit fly Drosophila melanogaster is an insect of tropical origin. Its larval stage is evolutionarily adapted for rapid growth and development under warm conditions and shows high sensitivity to cold. In this study, we further developed an optimal acclimation and freezing protocol that significantly improves larval freeze tolerance (an ability to survive at −5°C when most of the freezable fraction of water is converted to ice). Using the optimal protocol, freeze survival to adult stage increased from 0.7% to 12.6% in the larvae fed standard diet (agar, sugar, yeast, cornmeal). Next, we fed the larvae diets augmented with 31 different amino compounds, administered in different concentrations, and observed their effects on larval metabolomic composition, viability, rate of development and freeze tolerance. While some diet additives were toxic, others showed positive effects on freeze tolerance. Statistical correlation revealed tight association between high freeze tolerance and high levels of amino compounds involved in arginine and proline metabolism. Proline- and arginine-augmented diets showed the highest potential, improving freeze survival to 42.1% and 50.6%, respectively. Two plausible mechanisms by which high concentrations of proline and arginine might stimulate high freeze tolerance are discussed: (i) proline, probably in combination with trehalose, could reduce partial unfolding of proteins and prevent membrane fusions in the larvae exposed to thermal stress (prior to freezing) or during freeze dehydration; (ii) both arginine and proline are exceptional among amino compounds in their ability to form supramolecular aggregates which probably bind partially unfolded proteins and inhibit their aggregation under increasing freeze dehydration.
Programas de promoção da atividade física no Sistema Único de Saúde brasileiro: revisão sistemática
Authors: Becker Leonardo , Gonçalves Priscila , Reis Rodrigo 
Published: August 2016

O objetivo desta revisão foi sintetizar as evidências disponíveis na literatura referentes aos programas de promoção de atividade física (AF) no Sistema Único de Saúde brasileiro. Foi realizada uma busca sistemática da literatura nas bases de dados PubMed, Science Direct, Biblioteca Virtual de Saúde (BVS), base de dados de dissertações e teses e uma busca manual na Revista Brasileira de Atividade Física e Saúde (RBAFS) no período entre janeiro de 2005 à abril de 2015. Foram incluídos estudos: originais, realizados no Brasil, com desfecho a promoção da AF realizada no Sistema Único de Saúde em idiomas: Inglês, Espanhol e/ou Português. A análise final foi composta por 17 artigos. Desses, 29,41% (n=5) foram realizados em todo o território nacional e 5,88% (n=1) em duas ou mais regiões do país. Observou-se ainda uma disparidade regional, com 29,41% (n=5) dos estudos na região sudeste, 17,64% (n=3) na região sul, 11,76% (n=2) na região nordeste, apenas 5,88% (n=1) na região centro-oeste e nenhum estudo foi realizado na região norte do país. Enquanto ao modo de intervenção verificou-se que 47,05% (n=8) ocorreram no Sistema Único de Saúde e 47,05% (n=8) foram programas com equipe multiprofissional. Os estudos, em sua maioria forneceram dados descritivos ou sobre resultados na AF ou qualidade de vida, sendo escassas as informações sobre processo e impacto dos programas. Os programas com equipe multiprofissional foram estratégias importantes de promoção de AF. Sugere-se realizar estudos com delineamentos longitudinais ou mesmo experimentais, acerca do custo e benefício dos programas implementados.
EL FARM TOURISM COMO OPORTUNIDAD DE DESARROLLO SOSTENIBLE EN LAS REGIONES DEL SUR DE ITALIA
Authors: Belliggiano Angelo , De Rubertis Stefano 
Published: August 2016

Los argumentos en favor del turismo rural (rentabilidad, empleo, medio ambiente, etc.) hacen que el mismo se considere, sobre todo en las regiones más marginadas, uno de los principales asset estratégicos para el desarrollo local. No cabe duda alguna de que el turismo rural, especialmente el farm tourism, puede ayudar a perpetuar externalidades que flanquean la actividad agrícola (paisaje, biodiversidad, tradición, etc.), sobre todo cuando se trata de una forma de diversificación o reposicionamento del marco agrícola, en consonancia con el modelo multifuncional y postproductivista propuesto en las últimas políticas de la UE.Se registran, sin embargo, posiciones más conservadoras basadas en la evidencia, igual de fiable, que detecta elementos críticos relacionados con la sostenibilidad de la evolución alcista del número de turistas. Con este fin, el artículo muestra una comparación de la dinámica de las presencias registradas por el farm tourism en siete regiones del sur de Italia (entre 2001 y 2013) para evaluar, a través de la aplicación del Index Decomposition Analysis (IDA), algunas implicaciones de las reflexiones críticas relacionadas con la sostenibilidad del incremento del turismo rural.
Investigations of Titanium Implants Covered with Hydroxyapatite Layer
Authors: Świeczko – Żurek B. , Bartmański M. 
Published: August 2016

Abstract
To reduce unfavorable phenomena occurring after introducing an implant into human body various modifications of the surface are suggested. Such modifications may have significant impact on biocompatibility of metallic materials. The titanium and it's alloys are commonly used for joint and dental implants due to their high endurance, low plasticity modulus, good corrosion resistance as well as biocompatibility. Special attention should be given to titanium alloys containing zirconium, tantalum and niobium elements. These new generation alloys are used by worldwide engineering specialists. The experiments were performed with hydroxyapatite layer on titanium specimens with the use of electrophoresis method (different voltage and time).
Metoda i urządzenie do zmiany prędkości za pomocą obiegowej przekładni zębatej z zestawem stopniowanych kół planetarnych
Authors: Malashchenko Volodymyr , Strilets Oleh , Strilets Volodymyr 
Published: August 2016

Abstract
W artykule opisano nową metodę oraz urządzenie do sterowania płynną zmianą prędkości za pomocą wielostopniowej przekładni obiegowej wyposażonej w specjalnie ukształtowane koła planetarne oraz układ hydrauliczny z obiegiem zamkniętym, gdzie elementem służącym do regulacji prędkości jest albo zewnętrzne zębate koło pierścieniowe (wieniec), albo nośnik koła centralnego. W każdym przypadku element sterujący połączony z układem hydraulicznym z obiegiem zamkniętym może albo być w ruchu, albo nie poruszać się, w zależności od wielkości otwarcia przepustnicy regulacyjnej układu hydraulicznego. Przeprowadzono badania teoretyczne i za pomocą oprogramowania komputerowego otrzymano graficzne zależności pomiędzy prędkościami elementów napędzających, sterujących oraz napędzanych.
Jakościowe i ilościowe szacowanie ryzyka na podstawie analizy zdarzeń w lotnictwie wojskowym
Authors: Zieja Mariusz , Smoliński Henryk , Gołda Paweł 
Published: August 2016

Abstract
Zarządzanie ryzykiem rozumiane jest jako proces wspierający podejmowanie decyzji poprzez systemową ocenę możliwych sposobów działania, identyfikację zagrożeń i korzyści oraz wskazywanie najlepszego sposobu wykonywania zadań lotniczych.
W artykule przedstawiono metodologię jakościowego i ilościowego oszacowania ryzyka w oparciu o analizę zdarzeń lotniczych w lotnictwie wojskowym. Procedura proponowanego podejścia zawiera się w algorytmie szacowania stopnia prawdopodobieństwa i ważności oraz w kolejnych czynnościach: identyfikacji czynnika niebezpieczeństwa (CZN) danej kategorii, analizie ryzyka związanego z danym CZN, wyznaczeniu ryzyka, określeniu czynności korygujących, prognozowaniu ryzyka i jego weryfikacji w następnym okresie oceny. Na uproszczonym schemacie blokowym przedstawiono propozycję realizacji procedury jakościowego i ilościowego szacowania ryzyka z wykorzystaniem funkcjonującego w lotnictwie wojskowym systemu informatycznego TURAWA.
Zwiększenie możliwości detekcji ruchu różnicową metodą bazującą na subtrakcji tła poprzez jej integrację z algorytmem C-HDC
Authors: Kowaleczko Piotr , Rokita Przemysław 
Published: August 2016

Abstract
W niniejszej pracy zaprezentowana została metoda pozwalająca na zwiększenie możliwości wykrywania ruchomych obiektów przez konwencjonalny, różnicowy algorytm subtrakcji tła. Opracowany algorytm jest metodą hybrydową, łączącą różnicową metodę subtrakcji tła oraz algorytm obliczający przesunięcia histogramu konturowego (C-HDC – Contour Histogram Displacement Calculation). Poprawa niezawodności działania dotyczy sekwencji wideo zarejestrowanych przez ruchomą kamerę. W artykule zaprezentowano wyniki badań określające wpływ wprowadzenia poprawek na jakość otrzymywanych wyników detekcji.
Strong Cesàro summability and statistical limit of fourier integrals
Authors: Móricz Ferenc 
Published: August 2016

Abstract
In our previous paper [2], we introduced the concept of statistical limit of a measurable function and that of strong Cesàro summability of a locally integrable function. As an application, we proved there that the Fourier integral of a function ƒ ∈ L1(ℝ)∩C(ℝ) is strongly Cesàro summable and has statistical limit at every point of ℝ. The purpose of this paper is twofold:
(i) We prove that if ƒ ∈ L1(ℝ) is locally bounded on ℝ and continuous on an open interval J , then the strong Cesàro summability and the existence of the statistical limit of the Fourier integral of ƒ is uniform on J.
(ii) We complete and simplify the proof of [2, Statement (γ) of Theorem 3], which says that if ƒ ∈ L1(ℝ)∩C0(ℝ), then the conclusion in (i) is uniform on the whole ℝ.
On meromorphic functions that share one value with their derivative
Authors: Al-Khaladi Amer H.H. 
Published: August 2016

Abstract
The following theorem has been proved by R.Brück. If a non-constant entire function ƒ and its derivative ƒ′ share the value 1 CM (counting multiplicities), and if

, then ƒ′- 1 = c ( ƒ - 1 ) for some nonzero constant c . In this paper we shall prove that the above result is also true when ƒ is a non-constant meromorphic function.
Microbial Activity in the Large Intestine of Chicks Fed Diets with Different Types and Levels of Inulin
Authors: Bachanek Ilona , Barszcz Marcin , Taciak Marcin , Tuśnio Anna , Skomiał Jacek 
Published: August 2016

Abstract
The aim of the study was to evaluate the effects of dietary level of two types of inulin differing in the degree of polymerization (DP) on microbial activity in the large intestine of chicks. The experiment was performed on 70 one-day-old Ross 308 male chicks divided into 7 groups fed starter-type diets without inulin addition or supplemented with 0.2%, 0.4% or 0.6% of inulin with DP≥10 (IN10), or DP≥23 (IN23). After 14 days of feeding birds were sacrificed to collect digesta samples from caeca and colon. Caecal digesta was examined for pH, concentrations of short-chain fatty acids (SCFA) and amines, activities of β-glucosidase and mucinase, and relative amount of selected bacterial populations, whereas in colonic digesta only pH, SCFA and amines were analysed. Regardless of DP, inulin level did not affect digesta pH, activity of bacterial enzymes and relative amounts of Clostridium spp., Lactobacillus spp., Bifidobacterium spp. and E. coli populations. Dietary level of IN10 significantly affected propionic acid concentration, which was greater in caecal digesta of birds fed diet supplemented with 0.2% of IN10 compared to other groups and feeding diets supplemented with all levels of IN10 significantly reduced histamine concentration compared to the control. There were no effects of inulin on microbial activity indices in the colon. The present study indicates that, regardless of DP, inulin does not modify considerably microbial activity in the large intestine of chicks.
Impact of sex and diet on hematological and blood plasma biochemical profiles and liver histology of pikeperch (Sander lucioperca (L.))
Authors: Zakęś Zdzisław , Demska-Zakęś Krystyna , Szczepkowski Mirosław , Rożyński Maciej , Ziomek Elżbieta 
Published: August 2016

Abstract
The aim of the study was to determine the impact of diet and sex on the hematological and blood plasma biochemical profiles and the liver histology of pikeperch, Sander lucioperca (L.) reared in recirculating aquaculture systems (RAS) (initial mean body weight (BW) 1.35 kg). The proximate composition of the two commercial feeds used were (protein/lipid/nitrogen-free extracts) (P/L/NFE)) P505/L118/NFE294 g kg−1 (group I) and P471/L141/NFE290 g kg−1 (group II). Neither diet nor sex had a significant impact on final fish body weight (≈ 2.0 kg). Sex was noted to significantly impact glucose content (Glu – higher in males) and cholesterol (Chol – higher in females) in the blood plasma. Diet was confirmed to have a significant impact on levels of hematocrit (Ht), hemoglobin (Hb), and mean corpuscular hemoglobin (MCH), and the values of these indicators were higher in group I. Sex had a significant impact on Ht, Hb, MCH, and mean corpuscular hemoglobin concentration (MCHC), with higher values in male pikeperch. Diet and sex had significant impacts on the values of the pikeperch hepatosomatic index (HSI), hepatocyte size and that of their nuclei, and the values of the nucleocytoplasmic index (NCI).
Cannabis Control and Crime: Medicinal Use, Depenalization and the War on Drugs
Authors: Huber III Arthur , Newman Rebecca , LaFave Daniel 
Published: August 2016

Abstract
To date, 27 states and the District of Columbia have passed laws easing marijuana control. This paper examines the relationship between the legalization of medical marijuana, depenalization of possession, and the incidence of non-drug crime. Using state panel data from 1970 to 2012, results show evidence of 4–12 % reductions in robberies, larcenies, and burglaries due to the legalization of medical marijuana, but that depenalization has little effect and may instead increase crime rates. These effects are supported by null results for crimes unrelated to the cannabis market and are consistent with the supply-side effects of medicinal use that are absent from depenalization laws as well as existing evidence on the substitution between marijuana and alcohol. The findings contribute new evidence to the complex debate surrounding marijuana policy and the war on drugs.
Body composition and the level of fitness in 10 to 14-year-old girls in western Hungary: the impact of the new PE curriculum
Authors: Szakály Zsolt , Ihász Ferenc , Konczos Csaba , Fügedi Balázs , Bognár József 
Published: August 2016

Summary
Study aim: Over the last two decades, the body fat mass has been increasing and the level of physical fitness has been decreasing in school-aged children. Due to the health-related concerns that have arisen regarding school-aged children, the Hungarian government introduced everyday physical education in 2012. Since girls are more disposed to higher body fat and low fitness levels, the aim of our study was to characterise the physique, body composition and aerobic capacity of 10 to 14-year-old girls three years after the introduction of the new curriculum with daily PE lessons.

Material and methods: All of the primary schools that were selected to participate in this study serve as partnership schools in the University of West Hungary’s teacher training programme (N = 8). The sample included only those upper primary school girls (10 to 14 years of age) who participated in the everyday physical education lesson (N = 543). Standard anthropometric techniques and a 20m shuttle run test were selected for the analysis.

Results: An important result of this study was the finding that differences in the body composition features were consistently significant among the age groups. However, there were no differences among the age groups in the results of the 20 m multi-stage fitness test, nor in the girls’ relative aerobic capacity.

Conclusions: It can be presumed that an unfavourable body composition and poor fitness occur primarily in the prepuberty years. Everyday physical education serves as a good opportunity for shaping the girls’ fitness level and body composition, and also for encouraging healthy active living.
Von recklinghausen disease: one patient – various problems
Authors: Bergler-Czop B , Miziołek B , Brzezińska-Wcisło L 
Published: August 2016

Abstract
von Recklinghausen disease (vRD), more widely known as neurofibromatosis type 1, belongs to a group of genetic disorders and it is considered to be the most common genodermatosis. The disease has an autosomal dominant pattern of inheritance that involves mutations within the NF1 gene located on chromosome 17 in locus q11.2. The product of the NF1 gene is neurofibromin and the protein is well known to be a tumor suppressor factor. This counteracts possible overactivity of RAS (protein)/MAPK (mitogen-activated protein kinase) and RAS/PI3K/AKT/mTOR (phoshatydyloinositol-3-kinase/V-akt murine thy-moma viral oncogene homologue/mammalian target of rapamycin) signaling transduction pathways, preventing from uncontrolled cell proliferation and subsequent tumor formation. A loss of proper functioning of this protein leads to a development of vRD; however, a large variability in a phenotype of the disease and the onset of cutaneous findings, not necessarily in childhood, may provide a clinical diagnosis of the disease late in adulthood. We present a 52-year-old male in whom the diagnosis of vRD was proposed in the sixth decade of life, despite of multiple nodular lesions disseminated over the skin of the whole body and different neurological disturbances, not considered for a long time as manifestations of genodermatosis.
An alternative inhibition method for determining cross-reactive allergens
Authors: Schmidt-Hieltjes Yvonne , Teodorowicz Malgorzata , Jansen Ad , den Hartog Gerco , Elfvering-Berendsen Lisette , de Jong Nicolette W. , Savelkoul Huub F.J. , Ruinemans-Koerts Janneke 
Published: August 2016

Abstract

Background:
Inhibition assays are an useful tool to identify the allergen of primary sensitization of cross-reactive allergens. Classical ELISA-based inhibition assays are limited by both the availability of commercial standardized allergen extracts and the experience and knowledge needed for making home-made extracts. Moreover the direct comparison of the inhibition ELISAs outcomes between different laboratories is difficult because of different sources of used allergen extracts and a number of methodological variations. Therefore, we propose a novel ImmunoCap (Phadia, Thermofisher Scientific) based immunoinhibition method with the use of commercially available Caps as the allergen source.

Methods:
The novel ImmunoCap based immunoinhibition method was developed and tested with sera from patients with a well-known cross-reactive sensitization for fig (Ficus carica) and ficus (Ficus benjamina). Results were compared with a classically applied inhibition method, i.e. addition of homemade allergen extract to patient serum.

Results:
The amount of allergens (fig and ficus extracts) needed to reach a similar degree of inhibition was comparable for both inhibition methods.

Conclusions:
The ImmunoCap based inhibition assay, in addition to classical inhibition methods, is a valuable tool as the ImmunoCap analyzer and commercial allergens (Caps) are more widely available which makes the outcomes of inhibition tests comparable between different laboratories. Furthermore, in the ImmunoCap inhibition method the same protein source is used for both the inhibition of sIgE and sIgE measurement, which might be even more relevant when multiple cross-reactive allergens are tested.
Evaluation of the Impact of the EU Structural Support on the Competitiveness of Lithuanian Economics
Authors: Remeikiene Rita , Gaspareniene Ligita 
Published: August 2016

Abstract
The topic of competitiveness is becoming increasingly significant in the context of modern economics. Considering intensive processes of globalisation alongside with competitive pressure amongst the countries, competitiveness has become a necessary condition for successful economic and social development of any country. Only by creating, enforcing and maintaining international competitiveness of the country, rapid economic growth during the long term is achievable. Amongst the other urgent issues, the European Union (further the EU) public policies are also focused on competitiveness. After the failure to implement the Lisbon strategy and become “the most dynamic and competitive knowledge-based economy”, the EU declared its new competitiveness aims in the long-term strategy Europe 2020. Promotion of competitiveness is one of the fundamental aims and priority directions of the EU structural policy. The EU structural support is engaged as one of the public policy measures to promote the competitiveness of the member-states. In this context, it is purposeful to research whether the structural support is used efficiently and whether it actually contributes to the implementation of the defined aims. Under the order of various Lithuanian institutions, numerous studies on the efficiency of the EU structural support have been carried out. Nevertheless, by analysing the impact of the EU structural support, insufficient attention has been paid to the aspect of competitiveness. Considering the fact that Lithuania has entered the third programming period 2014-2020, evaluation of the EU structural investment in the country has become even more topical - for successful implementation of the aims raised for this new period, the analysis of the previous results is relevant. This determined formulation of the research problem: what impact does the EU structural support have on the competitiveness of Lithuanian economics? The empirical research has revealed that the EU structural support has a positive impact on Lithuanian gross domestic product growth, promotes foreign direct investment, research and development expenditure and increases the number of operating entities during 2004-2014 period.
The alternative negative constructions in spoken and written Korean: Logistic regression analysis
Authors: Kang Beom-mo 
Published: August 2016

AbstractAdopting quantitative corpus-based methods, this paper focuses on the alternative negative constructions in Korean, [anV] and [Vanhda]. Logistic regression analyses for a mixed-effects model were carried out on data drawn from the Sejong Korean Corpus. Certain features of the verb or adjective in negative constructions significantly affect the use of the two negative constructions. A relevant factor is register/medium (spoken or written), among other significant interactions of factors. Furthermore, the fact that frequency is consistent with other relevant factors, together with certain diachronic facts of Korean, supports the claim that frequency of use plays an important role in linguistic changes. Another finding is that, notwithstanding noticeable differences between spoken and written language, the factors influencing the use of the two negative constructions in Korean are largely similar in the spoken and written registers.