bluuebunny/crossref_metadata_2025_split huggingface dataset:
ESTIMATION OF HYDROXYCINNAMIC ACIDS CONTENT IN BERRY FRUITS
Authors: Миронов А.М. , Акимов М.Ю. , Кольцов В.А. , Жидехина Т.В. , Брыксин Д.М. , Хромов Н.В. 
Published: September 2024

Продукция с высоким содержанием гидроксикоричных кислот благотворно воздействует на здоровье человека. В связи с этим возрастает научный интерес к оценке содержания гидроксикоричных кислот в плодах ягодных культур. Количественное определение гидрокискоричных кислот проводили с помощью метода обращенно-фазовой высокоэффективной жидкостной хроматографии. В качестве стандартов использовали: хлорогеновую кислоту (Fluka), кофейную кислоту (Fluka), para-кумаровую кислоту (Sigma), тrans-коричную кислоту (Aldrich), цикориевую кислоту (Sigma), тrans-феруловую кислоту (Sigma). Объектами исследования служили плоды различных сортов ягодных культур (жимолость, ирга, кизил, крыжовник, малина, смородина красная, смородина черная). Наиболее высоким содержанием хлорогеновой кислоты характеризовались плоды смородины черной сортов Тамерлан (64,29 мг/100 г) и Чернавка (61,89 мг/100 г), кофейной кислоты — смородины черной сорта Зеленая дымка (9,36 мг/100 г), р-кумаровой кислоты — смородины черной сорта Тамерлан (8,41 мг/100 г), цикориевой кислоты — кизила сорта Аббат (1,23 мг/100 г), транс-феруловой кислоты — крыжовника сорта Kuršu Dzintars (0,89 мг/100 г), т-коричной кислоты — кизила сорта Волгоградский грушевидный (1,03 мг/100 г).
Products with a high content of hydroxycinnamic acids have beneficial effects on human health. In this regard, scientific interest in the evaluation of hydroxycinnamic acids content in berry fruits is increasing.Quantitative determination of hydroxycinnamic acids was carried out using reversed-phase high-performance liquid chromatography. Chlorogenic acid (Fluka), caffeic acid (Fluka), para-coumaric acid (Sigma), tranes-cinnamic acid (Aldrich), cichoric acid (Sigma), tranes-ferulic acid (Sigma) were used as standards. Fruit of berry crops (honeysuckle, honeysuckle, honeysuckle, cotoneaster, gooseberry, raspberry, red currant, black currant) served as objects of the study. The highest content of chlorogenic acid was observed in black currant fruits of Tamerlan (64.29 mg/100 g) and Chernavka (61.89 mg/100 g) varieties, caffeic acid — in black currant fruits of Green Smoke variety (9.36 mg/100 g), p-coumaric acid — black currant fruits of Tamerlan variety (8.41 mg/100 g), cichoric acid — in kizil Abbat berries (1.23 mg/100 g), trans-ferulic acid — gooseberry fruits of Kuršu Dzintars variety (0.89 mg/100 g), t-cinnamic acid — Volgograd pear-shaped kizil (1.03 mg/100 g).
ASSESSMENT OF STRAWBERRY SELECTED FORMS BY RESISTANCE TO RED STELE ROOT ROT (RPF1 GENE)
Authors: Лыжин А.С. , Лукъянчук И.В. 
Published: September 2024

Показаны результаты анализа аллельного состояния гена Rpf1 устойчивости к фитофторозной корневой гнили у гибридных форм земляники селекции «ФНЦ им. И.В. Мичурина». Аллель rpf1 в гомозиготном состоянии (восприимчивость к фитофторозу) идентифицирован у сеянцев 932-29 (F. virginiana subsp. platypetala × Фейерверк), 933-4 (F. virginiana subsp. platypetala × Рубиновый кулон), 62-7, 62-23 (Былинная × Фейерверк), 65-2, 65-15 (Олимпийская надежда × Былинная), 35-16 (922-67 × Maryshka). Гетерозиготное сочетание аллелей гена Rpf1 выявлено у гибридных сеянцев 69-29 (Фейерверк × Былинная), 62-41 (Былинная × Фейерверк), 72-24, 72-71 (Привлекательная × Былинная), 65-17, 65-24 (Олимпийская надежда × Былинная), что позволяет использовать их в селекции на устойчивость к P. fragariae var. fragariae в качестве ценных исходных форм.
The results of the analysis of allelic state of the Rpf1 red stele root rot resistance gene in strawberry hybrid forms created in the “I.V. Michurin FSC” were shown. Allele rpf1 in homozygous state (susceptibility to red stele root rot) was identified in strawberry seedlings 932-29 (F. virginiana subsp. platypetala × Feyerverk), 933-4 (F. virginiana subsp. platypetala × Rubinovyy kulon), 62- 7, 62-23 (Bylinnaya × Feyerverk), 65-2, 65-15 (Olimpiyskaya nadezhda × Bylinnaya) and 35-16 (922-67 × Maryshka). Heterozygous combination of Rpf1 gene alleles was identified in strawberry hybrids 69-29 (Feyerverk × Bylinnaya), 62-41 (Bylinnaya × Feyerverk), 72-24, 72-71 (Privlekatelnaya × Bylinnaya), 65-17, 65-24 (Olimpiyskaya nadezhda × Bylinnaya), which allows them to be used in breeding for resistance to P. fragariae var. fragariae as valuable initial forms.
ECOLOGICAL ASSESSMENT OF HYBRID SEEDLINGS RED CURRANTS
Authors: Родюкова О.С. 
Published: September 2024

Проведена оценка гибридных сеянцев, полученных от свободного опыления сортов смородины красной. Высокий выход сеянцев, устойчивых к абиотическим стрессорам получен в гибридном потомстве сортов Голландская розовая, Герой, Джонкер ван Тетс, устойчивых к антракнозу: Герой, Голландская розовая, Память Смольяниновой, устойчивых к листовой галловой тле: Виксне, Голландская розовая, Джонкер ван Тетс, Память Смольяниновой. Выделены перспективные формы с высоким уровнем хозяйственно-ценных признаков.
High yield seedlings that are resistant to abiotic stressors was obtained in hybrid progeny from free pollination of cultivars of Gollandskaya rozovaya, Geroyi, Jonkeer van Tets, resistant to anthracnose: the Geroyi, Gollandskaya rozovaya, Pamyat` Smol`yaninovoy, resistant to leaf gall aphids: Viksne, Gollandskaya rozovaya, Jonkeer van Tets, Pamyat` Smol`yaninovoy. Promising selected forms with a high level of economically valuable features are identified.
RELATIONSHIP OF COMPONENT COMPOSITION OF SUPERCRITICAL CO2 EXTRACTS OF WILD CARROTS WITH GROWING CONDITIONS
Authors: АЛИЕВ А. М. , РАДЖАБОВ Г. К. , ВАГАБОВА Ф. А. , ИСЛАМОВА Ф. И. , ГОРЯИНОВ С. В. , ХАЖЖАР Ф. ХАЖЖАР Ф. , ХАММАМИ С. ХАММАМИ С. 
Published: September 2024

Для изучения влияния экологических условий произрастания на химический состав растений проведена сверхкритическая углекислотная экстракция образцов моркови дикой Daucus carota subsp. maritimus, широко распространенной во всех регионах мира с умеренным климатом. С использованием методов газо-жидкостной хроматографии и масс -спектрального анализа в полученных экстрактах были определены летучие органические соединения, жирные кислоты и фитостерины находящиеся в изучаемых объектах. Показана зависимость химического состава моркови дикой от условий ее произрастания (температура, осадки, солнечная радиация и т. п.).
To study the influence of ecological growing conditions on the chemical composition of plants, supercritical carbon dioxide extraction of wild carrot samples, widespread in all regions of the world with a temperate climate (Daucus carota subsp. maritimus). Using the methods of gas-liquid chromatography and mass spectral analysis, volatile organic compounds, fatty acids and phytosterols in the studied objects were determined in the extracts obtained. The dependence of the chemical composition of wild carrots on its growing conditions (temperature,precipitation,solar radiation,etc.) is shown.
Impact of Hybrid Varieties on the Productivity of Rice Cultivation: The Case of Sindh, Pakistan
Authors: Abbasi Saqib 
Published: September 2024

Agriculture is a very important sector and crucial for poverty reduction and employment generation. The use of hybrid seeds leading to increased yield of crops and farmers’ income has been widely discussed in the literature. Through this study, an effort has been made to identify factors that impact obtaining high crop yield of rice by using the hybrid varieties. This study focuses on the use of hybrid varieties in the rice crop and presents a comparison in yield with the traditional open-pollinated varieties. The plot level information collected from eight major rice-producing districts of Sindh province of Pakistan was used to conduct this study and a propensity score matching technique was used to estimate the results of the study by using plot level variation between hybrid varieties and open-pollinated varieties. The results of the study showed significant improvement in rice yield with the adoption of hybrid rice varieties in the study area. This study highlights that the farmers have achieved a higher average yield of rice by using hybrid seeds as compared to open-pollinated varieties. Besides the crop yield, the overall income and profit of farmers have also increased by using hybrid seeds in the Sindh province. The study illustrates different interesting patterns relating to different characteristics of the household cultivating rice crops, different plot-level characteristics, and their comparison with hybrid and traditional varieties.
PREVALENSI DAN INTENSITAS EKTOPARASIT PADA IKAN BAWAL (Colossoma macropomum) YANG DI PELIHARA DALAM KARAMBA DI KELURAHAN PAHANDUT SEBERANG KOTA PALANGKA RAYA
Authors: Jumriyah Jumriyah , Rosita Rosita , Yasin Muhamad Noor , Maryani Maryani 
Published: September 2024

Penelitian ini bertujuan untuk mengetahui jenis ektoparasit, prevalensi dan intensitas ektoparasit ikan bawal pada karamba di Kelurahan Pahandut Seberang Kota Palangka Raya. Metode penelitian yang digunakan adalah metode penelitian deskriptif. Penelitian ini dilaksanakan pada tanggal 6 Februari - 29 Maret selama 3 minggu. Pengambilan sampel dilakukan pada 3 stasiun yaitu stasiun I, II dan III hilir yang dilakukan dengan interval 1 Pengambilan sampel ikan dilakukan setiap hari dalam 5 hari kerja dengan jumlah sampel ikan seharisebanyak 3 ekor selama 20 hari sehingga jumlah ikan selama penelitian berjumlah 60 ekor. Sampel ikan yang diambil di bawa dalam keadaan hidup dengan menggunakan box ke Laboratorium UPT Stasiun Karantina Ikan, Pengendalian Mutu dan Keamanan Hasil Perikanan Kota Palangka Raya Kalimantan Tengah untuk diperiksa ektoparasitnya. Hasil identifikasi ditemukan ektoparasit dimana prevalensi ikan bawal Prevalensi 38,33 % dan Intensitas 1,21 %. Organ sasaran yang diperiksa adalah insang, permukaan tubuh dan sirip. Hasil pengukuran kualitas air yaitu suhu, pH, DO, kecerahan dan kedalaman masih optimal untuk budidaya ikan bawal. suhu pada stasiun 1 rata-rata 27,6℃ stasiun II dengan rata-rata 28,4℃ dan stasiun III dengan rata-rata 27,4℃. Kecerahan pada stasiun I rata-rata 11,21 cm, stasiun II rata-rata 11 cm dan stasiun III rata-rata 12 cm serta pH pada stasiun I rata-rata 6,16, pada stasiun II rata-rata 6,15 dan pada stasiun III dengan rata-rata 6,11.
Sistem Manajemen Operasional PT Empat Bintang Luhur Berjaya
Authors: Sasongko Leonardo Bagus , Andarini M Sonja 
Published: September 2024

Artikel ini menyajikan hasil yang dilakukan di PT. Empat Bintang Luhur Berjaya, sebuah perusahaan yang berfokus pada manajemen operasional, pelatihan keamanan, manajemen K3, dan desain visual grafis. Tujuan kegiatan ini untuk memahami dan mengembangkan sistem manajemen operasional perusahaan. Kegiatan yang diamati adalah kegiatan operasional yang meliputi pembuatan jadwal pelatihan, pengelolaan dokumen administratif seperti surat rekomendasi dan surat tembusan, pembuatan laporan inventaris, proses administratif perjalanan dinas dan pemantauan pelatihan. Metodologi yang digunakan termasuk pemantauan langsung, partisipasi aktif, serta bimbingan dari pembimbing lapangan. Hasil akhir menunjukkan bahwa penerapan manajemen operasional yang efektif sangat penting untuk menjaga efisiensi dan efektivitas dalam pelaksanaan kegiatan perusahaan. Dalam perusahaan perencanaan, pengorganisasian, dan pengendalian menjadi faktor penting dalam manajemen operasional. Selain itu, keterampilan teknis dan soft skills seperti komunikasi, manajemen waktu, dan kerja sama tim perlu ditingkatkan agar tujuan perusahaan tercapai. Disini budaya kerja di PT. Empat Bintang Luhur Berjaya, serta proses administratif menjadi faktor yang mendukung kelancaran operasional perusahaan.
Pengaruh Return On Equity (ROE), Price Earning Ratio (PER), Arus Kas Operasi (AKO) dan Nilai Buku Ekuitas (NBE) Terhadap Harga Saham
Authors: Aisy Asri Rohadatul , Nursiam Nursiam 
Published: September 2024

Penelitian ini bertujuan untuk menganalisis dan mengetahui pengaruh Return On Equity (ROE), Price Earning Ratio (PER), Arus Kas Operasi (AKO), dan Nilai Buku Ekuitas (NBE) terhadap harga saham. Populasi penelitian ini adalah perusahaan LQ45 yang terdaftar di Bursa Efek Indonesia selama periode 2019-2022. Teknik pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling, dengan hasil 39 persahaan yang memenuhi kriteria yang telah ditentukan dengan jumlah sampel sebanyak 152 sampel. Penelitian ini menggunkan metode analisis data regresi berganda dengan bantuan program SPSS versi 25. Data yang digunakan dalam penelitian ini adalah adat sekunder yang diperoleh dari annual report yang diterbitkan perusahaan melalui website www.idx.co.id. Hasil penelitian ini menunjukkan bahwa variabel Return On Equity (ROE), Price Earning Ratio (PER), dan Nilai Buku Ekuitas (NBE) berpengaruh terhadap harga saham. Sedangkan Arus Kas Operasi (AKO) tidak berpengaruh terhadap harga saham
GC-MS Analysis and In-silico Molecular Docking of Phytoconstituents of Sansevieria roxburghiana against IL-1β and TNF-α for Anti-Rheumatic Activity
Authors: Sellapandian Aparna , Kumar J.Gopi Sudheer , S Kavimani , S Umamaheswari , Su Kayalvizhie , S Srinithi 
Published: September 2024

Background: Rheumatoid arthritis (RA) is recognized as a long-term inflammatory form of arthritis. This inflammation becomes long-lasting, and the synovial tissue thickens as a result of increased cell activity, protein production, and other variables in the joint, causing discomfort, redness, and warmth. It can also harm the joints of the hands, wrists, fingers, elbows, shoulders, toes, spinal column, and knees. Due to the autoimmune response, there is an aberrant production of inflammatory mediators such as Tumour necrosis factor- alpha (TNF-a), Interleukins (IL-1, IL-6, IL-7, IL-15, IL-17, IL-18, and IL-23), Granulocyte-macrophage colony-stimulating factor (GM-CSF), and Interferon (IFN)-ϒ. By inhibiting their production, those inflammatory mediators will play a pivotal role in the therapy of RA.
Purpose of the Study: The goal of the current study was to explore the anti-rheumatic activity of Sansevieria roxburghiana using the computational docking method.
Research Rationale: Administration of Non-steroidal anti-inflammatory drugs, steroidal medicaments, and Disease-modifying anti-rheumatoid therapies creates substantial adverse effects in people suffering with RA. To overcome the burdens and toxicity of drug products herbal medicines were taken into the field of research.
Materials and Methods: For this, 14 bioactive compounds from ethanolic extract of S. roxburghiana leaves were identified using the GC-MS (Gas chromatography-mass spectrometry) study and utilized as a binding compound (ligand) for biological target interactions. The crystallographic geometries of two targeted molecules, Interleukin-1β (IL-1β) and Tumour necrosis factor-alpha (TNF-α), have been retrieved from the PDB database. Methotrexate, a well-known medication for IL-1β and TNF-α inhibitors, was chosen as the reference for the comparative analysis. Computational docking was performed using the Autodock4 (version 1.5.6) choice based on the score functions.
Results: The results displayed the binding energy as follow -10.13, -9.77, -8.98 and -8.67 Kcal/mol of 2-isopropyl-5 methyl cyclohexyl 3-(1-(4-chlorophenyl)-3-oxobutyl)-C, 3-chloro-5-cholestene, stigmasterol, and cycloartanol against IL-1 β (PDB ID: 4GAI) and standard methotrexate was -8.14 Kcal/mol. For TNF-α (PDB ID: 5M2J) the binding energy is -8.94, -8.85, -8.46, and -8.24 Kcal/mol of cycloartanol, stigmasterol, 2-isopropyl-5 methyl cyclohexyl 3-(1-(4-chlorophenyl)-3-oxobutyl)-C and 3-chloro-5-cholestene by with comparing methotrexate (-8.89 Kcal/mol).
Conclusion: Hence, it was indicated that the phytoconstituents of S. roxburghiana could serve as a potential approach for designing future antirheumatic drugs.
КОНЦЕПТУАЛЬНІ ЗАСАДИ РОЗВИТКУ ВІДКРИТОЇ НАУКИ В НАПН УКРАЇНИ НА 2024-2030 РОКИ
Authors: Drach Iryna , Petroye Olha , Borodiyenko Oleksandra , Reheilo Iryna 
Published: September 2024

У статті висвітлено ключові положення «Концепції розвитку відкритої науки в НАПН України на 2024-2030 роки» (далі — Концепція), підготовленої колективом наукових працівників відділу дослідницької діяльності університетів Інституту вищої освіти НАПН України та презентованої на засіданні Президії НАПН України 22 серпня 2024 р. У Концепції представлено загальні положення, надано визначення основних понять, охарактеризовано цінності та принципи відкритої науки, проаналізовано сучасний стан, здобутки та з’ясовано проблеми щодо відкритої науки в НАПН України, обґрунтовано актуальність, визначено мету, завдання, окреслено шляхи та представлено очікувані результати впровадження Концепції відкритої науки в НАПН України.
ANALISIS POTENSI WILAYAH KOTA BUKITTINGGI, SUMATRA BARAT REGIONAL POTENTIAL ANALYSIS OF BUKITTINGGI CITY, WEST SUMATRA
Authors: Asnimar Duha  , Iqbal Ilvaldo  , Sera Junianti Sianturi  
Published: September 2024

Kota Bukittinggi adalah salah satu kota yang terletak di Propinsi Sumatera Barat. Walaupun tidak mempunyai potensi sumberdaya alam yang dapat dieksploitasi, kota Bukittinggi mempunyai potensi lain, yakni kondisi alam yang indah, udara yang sejuk, mempunyai tempat-tempat peninggalan bersejarah, serta terletak pada posisi yang strategis menjadikan kota ini berpotensi daerah kunjungan wisatawan yang dampaknya juga diharapkan dapat menjadi penggerak utama perekonomian kota. Penelitian ini berjudul Analisis Potensi Wilayah Kota Bukittinggi. Dengan tujuan akan mengamati sektor unggul yang memiliki potensi pada Kota Bukittinggi. Penelitian ini dilakukan dengan pendekatan analisis metode kajian pustaka (library research) yang berfungsi untuk membangun konsep atau teori yang menjadi dasar studi dalam penelitian. Keberadaan objek wisata di sekitar pusat kota telah mempengaruhi kegiatan dan potensi kota, dimana kegiatan dan usaha yang terkait dengan pariwisata tertarik untuk berlokasi mendekati objek wisata, dan membuka kawasan pasar seperti Pasar Atas di pelataran Jam Gadang sehingga dapat menarik wisatawan untuk berbelanja dan meningkatkan perekonomian kota. Selain itu Kota Bukittinggi sebagai Kota Pendidikan telah memiliki sarana dan prasarana pendidikan yang memadai karena saat ini telah tersedia 34 Taman Kanak-kanak, 59 Sekolah Dasar, 10 SLTP, 15 SMU, 13 SMK dan 18 Perguruan Tinggi. Jangkauan pelayanan pendidikan tidak hanya untuk putra daerah Kota Bukittinggi saja, akan tetapi meliputi Wilayah Sumatera Barat bagian Utara, sebagian Riau, Sumatera Utara dan Jambi.
Demographic and Clinical Characteristics of Patients with Primary Hypothyroidism and Adequacy of Levothyroxine Replacement Therapy in Them: A Nationwide Study in Bangladesh
Authors: Kamrul-Hasan A. B. M. , Mustari Marufa , Hannan Muhammad Abdul , Hoque Md Azizul , Chowdhury Emran Ur Rashid , Kabir Md Lutful , Kabir Md Ahamedul , Asaduzzaman Md , Hannan Mohammad Abdul , Mondal Ershad , Rahman Mohammad Motiur , Talukder Samir Kumar , Gaffar Md Abu Jar , Singha Swapan Kumar , Hassan Khaled , Selim Shahjada 
Published: September 2024

ABSTRACT

Background:
Despite the huge burden of primary hypothyroidism in Bangladesh, no nationwide study has been conducted describing the demographic and clinical characteristics of these patients; data on the adequacy of levothyroxine (L-T4) replacement are also lacking. This study aimed to fill the knowledge gap.

Materials and Methods:
This cross-sectional study was conducted among patients with primary hypothyroidism attending the endocrinology outpatient clinics of several hospitals throughout Bangladesh from July 2023 to December 2023. Adults with primary hypothyroidism who had been on L-T4 replacement for at least 1 year were included. Data on their demographic and disease-related characteristics were collected. Serum thyroid-stimulating hormone (TSH) was measured; TSH 0.4–4.0 μIU/mL was considered the therapeutic target for nonmalignant thyroid cases.

Results:
Two thousand six hundred and forty-one patients (median age 37 years, 86.4% female, and median disease duration 5 years) were included. Hashimoto’s thyroiditis was the most common (40.9%) cause of hypothyroidism; 1.9% had differentiated thyroid cancer (DTC), and the etiology was not established in many (40.2%). Only 26.8% of patients had high adherence to L-T4. Among the non-DTC cases (n = 2590), over half (53.9%) had TSH within the target range, whether the disease was uncontrolled in the remaining 46.1% (TSH was below the target range in 5.6% and above the target range in 40.5%). Among the DTC cases (n = 51), only a few (9.8%) had a TSH within the target range; TSH was below and above the range in 2% and 88.2% of these patients, respectively. In the nonmalignant hypothyroid cases, vegetarian diet, smokeless tobacco use, disease duration >5 years, iron or calcium supplements consumption within 4 h of L-T4 intake, and low or medium adherence to L-T4 were associated with uncontrolled hypothyroidism.

Conclusion:
For nearly half of Bangladeshi patients with primary hypothyroidism, L-T4 replacement is not optimal. Physicians should address the barriers to reaching the therapeutic goal for these patients.
Evaluation and comparison of the efficiency of ultrasonically activated intracanal irrigants grapeseed and pineapple extract in removing smear layer from the apical third of the root canal: An in vitro SEM analysis
Authors: Sebastian Nikita , Ashwini T. S. , Mahendran B. , Sowmya H. K. 
Published: September 2024

ABSTRACT

Aim:
This study aims to evaluate and compare the efficiency of grapeseed and pineapple extract in removing smear layer from the apical third of root canal, with and without ultrasonic activation.

Methods:
Eighty single-rooted permanent teeth were divided into two main groups: Group I: conventional syringe irrigation and Group II: ultrasonic activation. Each group was subdivided into two experimental groups, i.e. grapeseed and pineapple extract and one control group, i.e., 17% ethylenediaminetetraacetic acid (EDTA). For each subgroup, instrumentation was done using ProTaper Gold up to size F3 and irrigated with 5 mL of the respective irrigant, followed by a final rinse of 2.5 mL of 5.25% NaOCl. For Group II, the respective irrigant was ultrasonically activated for 1 min, followed by a final rinse of 2.5 mL of 5.25% NaOCl. Smear layer evaluation was done with scanning electron microscope, and data were statistically analyzed.

Results:
In Group I, both pineapple and grapeseed extracts were more effective than 17% EDTA in removing smear layer from the apical root canal. However, in Group II, 17% EDTA showed highest efficacy in smear layer removal, followed by pineapple and grapeseed extracts (P < 0.05).

Conclusion:
Natural extracts such as pineapple and grapeseed seeds extracts exhibit potential for smear layer removal in the apical third, without the disadvantage of dentinal erosion from synthetic smear layer removing agents.