bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between misfolded alpha‐synuclein aggregates and Alzheimer's disease pathology in vivo
Authors: Pichet Binette Alexa , Mammana Angela , Wisse Laura , Rossi Marcello , Strandberg Olof , Smith Ruben , Mattsson‐Carlgren Niklas , Janelidze Shorena , Palmqvist Sebastian ,   ADNI, Ticca Alice , Stomrud Erik , Parchi Piero , Hansson Oskar 
Published: September 2024

AbstractINTRODUCTIONWe examined the relations of misfolded alpha synuclein (α‐synuclein) with Alzheimer's disease (AD) biomarkers in two large independent cohorts.METHODSWe included Biomarkers for Identifying Neurodegenerative Disorders Early and Reliably Two (BioFINDER‐2) and Alzheimer's Disease Neuroimaging Initiative (ADNI) participants (n = 2315, cognitively unimpaired, mild cognitive impairment, AD dementia) who had cross‐sectional cerebrospinal fluid (CSF) α‐synuclein measurement from seed‐amplification assay as well as cross‐sectional and longitudinal amyloid beta (Aβ) and tau levels (measured in CSF and/or by positron emission tomography). All analyses were adjusted for age, sex, and cognitive status.RESULTSAcross cohorts, the main biomarker associated with α‐synuclein positivity at baseline was higher levels of Aβ pathology (all p values ≤ 0.02), but not tau. Looking at longitudinal measures of AD biomarkers, α‐synuclein –positive participants had a statistically significant faster increase of Aβ load, although of modest magnitude (1.11 Centiloid/year, p = 0.02), compared to α‐synuclein –negative participants in BioFINDER‐2 but not in ADNI.DISCUSSIONWe showed associations between concurrent misfolded α‐synuclein and Aβ levels, providing in vivo evidence of links between these two molecular disease pathways in humans.Highlights:
Amyloid beta (Aβ), but not tau, was associated with alpha‐synuclein (α‐synuclein) positivity.
Such association was consistent across two cohorts, beyond the effect of age, sex, and cognitive status.
α‐synuclein–positive participants had a small, statistically significant faster increase in Aβ positron emission tomography levels in one of the two cohorts.
Mechanism investigation on selective adsorption of fabric loaded with calcium silicate for organic dyes
Authors: Bai Yulian , Jia Guozhi 
Published: September 2024

AbstractSelective adsorption plays an important role in the resource utilization of dye wastewater. Hydrated calcium silicate (CSH), as an ideal adsorption material, is successfully compounded on the surface of polypropylene (PP) fibric by quasi‐solid‐phase method, and porous calcium silicate film is formed on the surface of PP fabric. The contact angle of the surface of PP fibers is changed from 130.7° to 62.4° due to the hydrophilic characteristics of CSH and polyvinyl alcohol. The adsorption for dyes shows obvious selectivity, and the removal ratio for methylene blue can reach more than 90%, while there is almost no adsorption for methyl orange. The obvious selectivity can be attributed to the electrostatic interaction between CSH and dyes. CSH contains silicate anion chains, resulting in a large number of negatively charged sites distributed on the surface, which may be the main reason for the adsorption for cationic dyes through electrostatic interactions. The investigation of adsorption kinetics shows that the formation of coordination bonds between calcium silicate and methylene blue will also lead to further enhancement of adsorption capacity.
Renal transplant nephrolithiasis: Presentation, management and follow‐up with control comparisons
Authors: Sandberg Maxwell , Cohen Adam , Escott Megan , Marie‐Costa Claudia , Temple Davis , Rodriguez Rainer , Gordon Alex , Rong Anita , Andres‐Robusto Brian , Roebuck Emily H. , Ye Emily , Underwood Gavin , Choudhary Arjun , Whitman Wyatt , Webb Christopher J. , Stratta Robert J. , Wood Kyle , Assimos Dean , Mirzazadeh Majid 
Published: September 2024

AbstractObjectivesTo analyse the presentation, management and long‐term outcomes of renal transplant patients who formed kidney stones in their allograft. The secondary aim was to identify risk factors for stone formation in this cohort.Materials and MethodsPatient information from an institutional renal transplant database was used to identify individuals who both did and did not form kidney stones following renal transplantation. Computerized tomography (CT) imaging was used to make the diagnosis of kidney stones and measure stone size. Age‐ and gender‐matched controls never forming a stone in their allograft were used for comparative analysis to identify risk factors for stone formation in transplant patients.ResultsA total of 8835 transplant patients were included in the study, of which 128 (1.4%) formed a kidney stone in their allograft after surgery. The mean time to kidney stone identification was 6.2 years, and the mean number of stones formed was 1.7, with a mean maximum size dimension on a CT scan of 5.7 mm per stone. A total of 26 patients were subjected to stone‐removing procedures, the most common being ureteroscopy (42.3%). The primary intervention failed in eight patients requiring a secondary intervention, and percutaneous nephrolithotomy (PCNL) had the lowest success rate (60%). A total of 164 controls were identified. In comparison to controls, stone formers had lower serum calcium (p = 0.008), lower estimated glomerular filtration rates (p = 0.019), higher lymphocyte counts (p = 0.021) and greater rate of urinary tract infection (p = 0.003). Graft failure rates were the same (p = 0.524), but time to graft failure was significantly longer in stone patients compared with controls (p = 0.008).ConclusionsThe rate of stone formation is low in transplant patients. Success rates for stone treatment vary based on the surgery selected, with PCNL being the worst. Graft survival rates were equivocal, but survival time was better in stone patients. Our analysis calls for further investigation of this important topic.
Survival of Children With Critical Congenital Heart Defects in the National Birth Defects Prevention Study
Authors: Forestieri Nina E. , Olshan Andrew F. , Oster Matthew E. , Ailes Elizabeth C. , Fundora Michael P. , Fisher Sarah C. , Shumate Charles , Romitti Paul A. , F. Liberman Rebecca , Nembhard Wendy N. , Carmichael Suzan L. , Desrosiers Tania A. ,   The National Birth Defects Prevention Study
Published: September 2024

ABSTRACTBackgroundCritical congenital heart defects (CCHDs) are associated with considerable morbidity and mortality. This study estimated survival of children with nonsyndromic CCHDs and evaluated relationships between exposures of interest and survival by CCHD severity (univentricular or biventricular function).MethodsThis analysis included 4380 infants with CCHDs (cases) born during 1999–2011 and enrolled in the National Birth Defects Prevention Study, a multisite, population‐based case–control study of major birth defects. Cases were linked to state death files. Nonparametric Kaplan–Meier survival functions were used to estimate 1‐ and 5‐year survival probabilities overall and by severity group (univentricular/biventricular) stratified by demographic and clinical exposure variables of interest. The log‐rank test was used to determine whether stratified survival curves were equivalent. Survival and 95% confidence intervals (CIs) were also estimated using Cox proportional hazards modeling adjusted for maternal age, education, race/ethnicity, study site, and birth year.ResultsOne‐ and five‐year survival rates were 85.8% (CI 84.7–86.8) and 83.7% (CI 82.5–84.9), respectively. Univentricular 5‐year survival was lower than biventricular case survival [65.3% (CI 61.7–68.5) vs. 89.0% (CI 87.8–90.1; p < 0.001)]. Clinical factors (e.g. preterm birth, low birthweight, and complex/multiple defects) were associated with lower survival in each severity group. Sociodemographic factors (non‐Hispanic Black race/ethnicity, <high school education, smoking, and lower household income) were only associated with survival among biventricular cases.ConclusionsMortality among children with CCHDs occurred primarily in the first year of life. Survival was lower for those with univentricular defects, and social determinants of health were most important in predicting survival for those with biventricular defects.
Exploring social goal orientations, self‐perceptions and popularity with students attending regular and special education schools
Authors: Goagoses Naska , Eilts Jule 
Published: September 2024

AbstractEmbedded within social dynamics and social‐information processing, the current qualitative study explores the social goal orientations, self‐perceptions and perceptions of popularity of students attending regular and special education schools in Germany. Semi‐structured interviews were conducted with seven students in Grade 8, of which three were attending a special educational school specialised in supporting social‐emotional development. Students' endorsement of leadership, intimacy, nurturance and popularity goals were determined, with a focus on the strategies they employ for attainment within everyday social encounters. A range of strategies emerged, including communication strategies, humour and prosocial spending, which expands on past literature that only focused generalised behavioural tendencies and responses to conflict situations. Furthermore, students named both agentic and communal traits when describing how their peers view them. Lastly, students' perspective of popularity characteristics was explored, which thus far has only received minimal inquiry in Germany. This resulted in a collection of conditions, traits and behaviours required for popularity, with both similarities and differences in comparison to other European countries. The inclusion of both students attending regular and special education schools, offered new perspectives and contributed towards addressing knowledge gaps, generating insights and conceptual understandings, as well as offering directions for future research endeavours.
Optimization and Reaction Kinetics of Catalytic Transfer Hydrogenation of 5‐Hydroxymethylfurfural to 2,5‐Dimethylfuran over CuCoOx Catalysts
Authors: Yan Ziyi , Wang Xiaofeng , Zeng Fandi , Li Qingbo , Liang Xinhua 
Published: September 2024

AbstractFrom the perspective of reaction kinetics, the catalytic transfer hydrogenation (CTH) reaction of 5‐hydroxymethylfurfural (HMF) was studied in this work. Its hydrogenation product, 2,5‐dimethylfuran (DMF), was a stable and water‐insoluble biofuel alternative to gasoline. In this study, CuCoOx catalysts were used and 2‐propanol (IPA) was the hydrogen donor. The results exhibited that the HMF conversion reached 100% with the complete formation of DMF at 170 °C. Experimental and characterization results revealed that the balance of metal sites and acid sites was critical, which could inhibit the side reactions and enhance the yield of the target product. By adopting the Langmuir–Hinshelwood–Hougen–Watson (LHHW) kinetic model, it was found that direct hydrogen transfer from IPA to HMF predominated over indirect transfer via H2. Moreover, the results revealed that the hydrogenolysis of 2,5‐bis(hydroxymethyl)furan to 5‐methyl furfuryl alcohol was the rate‐limiting step. The kinetic study in this work is expected to provide valuable insights into the industrial optimization of the CTH reaction of HMF and lay the foundation for the study of hydrogen transfer pathways in this process.
“Modernization of Railway Track Pardubice –Stéblová: New steel bridge over Labe river”
Authors: Mitlöhner Jan 
Published: September 2024

AbstractThe construction of a new double‐track steel railway arch bridge over the Elbe river, which replaced the original single‐track bridge from 1966, has significantly increased the capacity, speed, and smoothness of railway traffic in Pardubice. This 140‐meter‐long, three‐span bridge was realized as part of the modernization and double‐tracking of the Pardubice ‐ Hradec Králové line between 2021‐2024. Its construction, coupled with the provisional use of the original bridge, represents a remarkable engineering feat
Development of a lamella‐model to evaluate stresses caused by hot asphalt installation
Authors: Händeler Damian , Geßler Achim , Wolters Kevin , Feldmann Markus 
Published: September 2024

AbstractOn road‐bridges hot asphalt is installed to provide a level and waterproof surface. That wearing surface, however, needs occasional renewal. On a number of steel highway‐bridges it has been observed that after such asphalt‐renewal fatigue‐cracks have increasingly occurred at the welds of orthotropic bridge‐decks. The German Federal Highway Research Institute has assigned a research project to RWTH Aachen University to evaluate the response of steel‐bridges to time‐ and location‐dependent, nonlinear temperature profiles. Since FEM‐software with the needed level of detailing could not provide solutions for long large‐span bridges, a software‐based lamella‐model was developed. This model enables the partition of the bridge into rectangular beam‐lamella, precisely considers the nonlinear temperature and calculates the inner forces and displacements along the bridge. This paper presents the theoretical background of the lamella‐program as well as results calculated exemplary for a 742m‐long German highway‐bridge including validation with in situ temperature and strain measurements during asphalting.
The pedestrian and bicycle bridge “Sprung über die Emscher” in Castrop Rauxel
Authors: Grubmüller Sascha , Dorrer Günther 
Published: September 2024

AbstractThe new pedestrian and bicycle bridge in Castrop Rauxel is part of the “Emscherland” project, a nature and water experience park. “Emscherland” is a joint project of the Emschergenossenschaft with the adjacent municipalities of Castrop‐Rauxel, Recklinghausen, Herne and Herten.The total length of the bridge is 412 meters, and the usable width of the pedestrian and bike path is 2.50 meters. The weight of the steel structure is 900 tons. A highlight of the assembly work is the floating‐in of the bridge section (70 meters long and weighing 105 tons) over the Rhein‐Herne‐Canal.
Material selection for railroad bridge bearings to avoid brittle fracture
Authors: Hoyer Natalie , Kühn Bertram 
Published: September 2024

AbstractSteel structures are typically engineered for the upper range of the steel toughness‐temperature curve. To account for the reduction in toughness properties within the temperature transition range, additional safety assessments are necessary. These assessments rely on fracture mechanics considerations and enable the selection of an adequate steel material to prevent brittle fracture. Considering this context, recommendations were already put forth in 2011 to govern the appropriate choice of steel grades for bearing components. However, these recommendations are no longer entirely current in light of more recent findings. As a result, the German Centre for Rail Traffic Research has called a research project with the aim to formulate proposals to expand the regulatory framework related to suitable material selection, aimed at preventing brittle fracture in bridge bearings.
DYNAMIC BEHAVIOUR AND DAMPING OF STEEL RAILWAY BRIDGES AT A SPEED OF 200 KM/H
Authors: Ryjáček Pavel , Polák Michal , Dynybyl Vojtěch , Litoš Jiří 
Published: September 2024

AbstractThe subject of the paper is the comprehensive information on experiments carried out on a group of railway bridges near Břeclav, Vranovice and Soběslav, covering filler beams, steel girder bridges and composite bridges. The subject was to determine the behavior of bridges at higher speeds and to determine the value of damping as a basis for the preparation of HSR lines in the Czech Republic.This paper describes the structures investigated and recapitulates selected findings, particularly related to the damping. Also, the general findings from a number of tests focusing on damping are also given.
Cable‐stayed footbridge in Lover Vítkovice Area‐DOV
Authors: Janečko Jakub , Janata Vladimír , Lahodný Jiří 
Published: September 2024

AbstractA cable‐stayed footbridge for pedestrians and cyclists is situated in post‐industrial landscape Lover Vitkovice Area (DOV) of Ostrava. The bridge has two independent sections, 84,3 m and 68,3 m long that leads across the Ostravice river and the railway corridor directly towards the recent blast furnace. The bearing structure consists of outer lattice trusses and the lower steel orthotropic deck and is characterised by outstanding variable shape created by architect. The bridge's deck is supported by three and two pairs of cables, which run directly from top of the middle stiff pylon. Cables are connected to bottom chords of the structure by cylindrical fork with threaded rod and the tie rod structural system with rolled thread (turnbuckles, forks with pin and conical lock covers). The paper describes manufacturing, erection and pre‐stressing procedure, dynamic properties and design and installation of tuned mass dampers.
The effect of green human resource management on employee green behavior
Authors: Yadate Dejene Adugna 
Published: September 2024

AbstractThe main objective of the study is to examine the effect of Green Human Resource Management (GHRM) on employee green behaviors (EGB) (transforming, conserving, influencing others, taking initiatives, and avoiding behaviors) in the case of Hawassa University staff. Using a straightforward random sampling method, 252 sample responses were selected from the target population of 680 academic staff members. A descriptive and explanatory research design was employed in the study, and a questionnaire was used to gather data. Structural equation modeling was used to examine the effect of GHRM on EGB. Confirmatory factor analysis was used to test a predefined factor structure and assess the reliability and validity of the model. The study result shows GHRM has a statistically significant positive effect on conserving and influencing the behavior of other employees. On the other hand, GHRM has a negative and significant effect on avoiding harm and has no statistically significant effect on transforming and taking initiatives in categories of EGB. This study contributes to the body of knowledge in two ways. First, this study examines the role of GHRM on green employees' behavior by taking Hawassa University staff as a case study, which hasn't been conducted so far by other researchers. Secondly, the research examines the effect of GHRM on EGB by assessing employee behavior from various perspectives based on the green five taxonomy of EGB, which has not been sufficiently employed by prior studies. Besides the study, add green employee relations as an additional factor in GHRM, which was overlooked by most studies.
Ornithophily in the trumpet creeper (Campsis radicans)
Authors: Graves Gary R. 
Published: September 2024

AbstractThe diversification of hummingbirds (Trochilidae) has shaped the pollination strategies and floral trait evolution in at least 68 families of flowering plants in the Western Hemisphere. The trumpet creeper (Bignoniaceae) is the quintessential example of ornithophily in eastern North America. The mutualistic relationship between this orange‐flowered liana and the ruby‐throated hummingbird (Archilochus colubris) was illustrated as early as 1731. However, neither historical nor modern accounts accurately describe the feeding behavior of ruby‐throats at trumpet creeper flowers or the floral adaptations for ornithophily. This paper explores their surprisingly immersive mode of foraging at trumpet creeper flowers and quantitatively assesses floral traits in two populations in the Ozark Mountains. The ruby‐throat's bill is approximately one‐third the length of the trumpet‐shaped flowers, which counters the tendency for the corolla length of ornithophilous plants to match the bill length of their principal hummingbird pollinator. To access the nectary, ruby‐throats grasp or cling to the ventral petal lobe of the corolla with their claws and thrust their head and upper body into the flower. This immersive “floral‐diving” had not been formally documented among the 356 species of hummingbirds until now. The didynamous anthers and stigma are strategically positioned inside the corolla to brush the crown feathers when the ruby‐throat inserts its head. A narrow stricture in the corolla, about a third of the way up, allows the bill and tongue of hummingbirds to pass while blocking bumblebees and carpenter bees from reaching the nectary. As a result, the abundant sucrose‐rich floral nectar seems to be reserved for hummingbird pollinators.
Evaluation of forest ecosystem resilience to drought considering lagged effects of drought
Authors: Xu Qingfeng , Yu Ruyue , Guo Lili 
Published: September 2024

AbstractDrought can cause significant disruption to forest ecosystems and may have long‐term impacts on the structure and function of ecosystems after the end of drought. This is the key to quantifying the ability of ecosystem to respond to disturbance events by comprehensively analyzing the impact of drought on vegetation, the lagged effect, and ecosystem resilience to drought. This article takes broad‐leaved forests and coniferous forests in multiple temperature zones of China as the object of study, using distributed lagged nonlinear model (DLNM) to construct a systematic method. Our results show that the main sensitive lagged time for coniferous forests and broad‐leaved forests is the first 3 months in various temperature zones, with the strongest lagged effect in the month when the drought incidents occur. Coping capacity represents ecosystems to remain stable during droughts, and we quantified the indicator by the ratio of the resistance (the difference between NDVI value before the drought and during the drought) to recovery (the difference between NDVI value after the drought and during the drought). When dealing with intensive drought events, the coping capacity of subtropical broad‐leaved forests (−0.67) and tropical broad‐leaved forests (−0.88) exhibit the strongest coping capacity (value tends to −1). Overall, vegetation growth in subtropical and tropical regions is less affected by drought compared to temperate and cold temperate zones. The research results help us understand the comprehensive impact of drought on vegetation and the strategies for different vegetation to cope with drought.
Inorganic film materials for flexible electronics: A brief overview, properties, and applications
Authors: Kanon Kamruzzaman , Sharif S. Sadakat , Irfan Ahmad , Sharif Ahmed 
Published: September 2024

AbstractThe field of flexible electronics has experienced remarkable expansion in response to the escalating demand for lightweight, bendable, and multifunctional electronic devices. As the world increasingly integrates electronics seamlessly into everyday life, the importance of flexible electronics becomes more apparent. While existing reviews have examined materials used in flexible devices, they often overly focus on specific materials or provide broad generalizations about different material types. Thus, this review offers a concise yet comprehensive overview of critical inorganic film materials crucial to the advancement of flexible and wearable devices. Each material is introduced with a succinct overview of its structure and production processes. This review elucidates their unique characteristics and potential applications in flexible electronics by comparing their mechanical, electrical, and thermal properties. This review is a valuable resource for researchers entering this emerging field of flexible electronics, providing a concise yet comprehensive insight and property comparisons. Accompanied by figures illustrating material structures and applications, readers will gain access to summarized discussions. Comparative figures of material properties will enhance comprehension. Additionally, discussions on diverse applications will offer insight into their versatility across various fields of flexible electronics.