bluuebunny/crossref_metadata_2025_split huggingface dataset:
Für die Menschen – gegen Ausgrenzung
Authors: Oehmcke Birgit 
Published: July 2017

Zusammenfassung
Aktionsbündnis Seelische Gesundheit Seit über zehn Jahren setzt sich das
Aktionsbündnis Seelische Gesundheit mit seiner Anti-Stigma-Arbeit für die
soziale Integration und Akzeptanz von psychisch erkrankten Menschen in
Deutschland ein. Dazu wurden in den letzten Jahren umfassende
Aufklärungskampagnen in wichtigen gesellschaftlichen Bereichen entwickelt und
umgesetzt. Ziel ist es, der Öffentlichkeit zu vermitteln, dass psychische
Störungen therapierbar sind und jeden betreffen können. Menschen sollen
ermuntert werden, Hilfe in Anspruch zu nehmen. Gleichzeitig sollen Ängste und
Vorurteile gegenüber den Betroffenen abgebaut werden.
Eine Wirklichkeit, verschiedene Blickwinkel
Authors: Bauer Ronja 
Published: July 2017

Zusammenfassung
Protokoll Im vorherigen Beitrag haben wir Ihnen die Grundlagen und den
Ablauf der systemischen Fallbesprechung dargestellt. An dieser Stelle startet
nun unsere neue Serie, in der wir in jeder Ausgabe das Protokoll eines
Weiterbildungsteilnehmers veröffentlichen. So erhalten Sie einen transparenten
Einblick in den Ablauf der Fallbesprechungen. Außerdem möchten wir Sie einladen,
sich selbst in die verschiedenen Rollen hineinzuversetzen. Fallen Ihnen weitere
Lösungswege ein? Dann schreiben Sie uns an psych.pflegeheute@thieme.de.
The boundaries of belonging
Authors: Jaspers Jürgen 
Published: July 2017

Abstract
The chapters in this section form a fascinating combination in describing how quite different types of speakers negotiate a radical uprooting of their self-understanding, sense of place, and belonging. From the Bosavi villagers struggling to redefine themselves in the face of religious colonization in Bambi Schieffelin’s chapter, to the elderly miners still honoring their local speech style long after the forces of deindustrialization atrophied their community in the chapter by Peter Auer and Leonie Cornips, to the isolated Japanese expatriate wives who are trying to (re)create some kind of connectedness in Anna Banaś’ chapter, in each of these analyses we see speakers maintaining ways of belonging in the face of serious adversity. Below I will first explain that ideas of language, place and belonging are strongly influenced by discourses of modernity, and that sociolinguists have been trying to go beyond the legacy of this master narrative, before addressing the linguistic ways in which the speakers discussed in these chapters set out to construct a sense of place, group, and belonging.
Playing against peripheralization
Authors: Woolard Kathryn A. 
Published: July 2017

Abstract
The three chapters in this section make a mutually informing set that is as intellectually rewarding as it is fun to read. They share a center-periphery analytic frame with other contributions in the volume, but they are distinguished as a set by their shared focus on what Sari Pietikäinen (2016) calls carnivalesque critique, quite literally in the Limburgian event that Lotte Thissen examines. In all of these cases, minoritized speakers use humor, parody, and/or ritualized spectacle to disrupt the center-periphery framework and to subvert peripheralization. In turn, the three cases differ from and complement each other by revealing varying techniques that actors in specific marginalized communities use to carry out such disruption. In the following sections of this commentary I will first examine some facets of the center-periphery theoretical framework that seem especially relevant to sociolinguistic work. I will then consider both the shared and the different techniques of humorous contestation that these papers illuminate.
Peripheral performances
Authors: Stengs Irene 
Published: July 2017

Abstract
This contribution focusses on the languagecultural politics played out in performances of André Rieu, the World’s King of the Waltz. At stake are stereotypical oppositions made within the Netherlands between ‘the nation’s center’ (‘Holland’) and the ‘peripheral’ province of Limburg. During his concerts in the Limburgian capital Maastricht, Rieu’s hometown, Rieu negates the Hollanders-centered, taken-for-granted, perspective that foregrounds Standard Dutch and its speakers as the normative neutral. Presenting himself as a global-cum-local performer alternating local language with English, Rieu marginalizes Standard Dutch as irrelevant, in the Dutch language-scape usually the position of dialects. Rieu’s languagecultural political messages are persuasive because of his strategic, jocular use of various linguistic and cultural resources, all to highlight his belonging to Maastricht.
APMP key comparison of DC voltage at 1.018 V and 10 V
Authors: Kim Kyu-Tae , Maruyama Michitaka , Solve Stephane , Marais Louis , Abidin Abdul Rashid B Zainal , Chua Sze Wey , Lee Dennis , Huang Chun-feng , Pimsut Sittisak , Nurlan Seksembayev 
Published: July 2017

A key comparison of DC voltage at 1.018 V and 10 V has been conducted from 2009 to 2011 between APMP member laboratories and the BIPM. All participants' results (except one) are within the uncertainty of comparison reference value and also within the uncertainty of the CIPM key comparison reference value of the BIPM.EM-K11.3, approximately 0.08 μV/V for 10 V and 0.2 μV/V for 1.018 V (k=2). The result of the comparison is supposed to successfully provide participating laboratories with the opportunity to compare national standards within the region, and to support participants' entries in Appendix C of the Mutual Recognition Arrangement.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
An expanded mammal mitogenome dataset from Southeast Asia
Authors: Mohd Salleh Faezah , Ramos-Madrigal Jazmín , Peñaloza Fernando , Liu Shanlin , Mikkel-Holger S. Sinding , Riddhi P. Patel , Martins Renata , Lenz Dorina , Fickel Jörns , Roos Christian , Shamsir Mohd Shahir , Azman Mohammad Shahfiz , Burton K. Lim , Stephen J. Rossiter , Wilting Andreas , Gilbert M. Thomas P. 
Published: July 2017

Abstract
Southeast (SE) Asia is 1 of the most biodiverse regions in the world, and it holds approximately 20% of all mammal species. Despite this, the majority of SE Asia's genetic diversity is still poorly characterized. The growing interest in using environmental DNA to assess and monitor SE Asian species, in particular threatened mammals—has created the urgent need to expand the available reference database of mitochondrial barcode and complete mitogenome sequences. We have partially addressed this need by generating 72 new mitogenome sequences reconstructed from DNA isolated from a range of historical and modern tissue samples. Approximately 55 gigabases of raw sequence were generated. From this data, we assembled 72 complete mitogenome sequences, with an average depth of coverage of ×102.9 and ×55.2 for modern samples and historical samples, respectively. This dataset represents 52 species, of which 30 species had no previous mitogenome data available. The mitogenomes were geotagged to their sampling location, where known, to display a detailed geographical distribution of the species. Our new database of 52 taxa will strongly enhance the utility of environmental DNA approaches for monitoring mammals in SE Asia as it greatly increases the likelihoods that identification of metabarcoding sequencing reads can be assigned to reference sequences. This magnifies the confidence in species detections and thus allows more robust surveys and monitoring programmes of SE Asia's threatened mammal biodiversity. The extensive collections of historical samples from SE Asia in western and SE Asian museums should serve as additional valuable material to further enrich this reference database.
The pearl oyster Pinctada fucata martensii genome and multi-omic analyses provide insights into biomineralization
Authors: Du Xiaodong , Fan Guangyi , Jiao Yu , Zhang He , Guo Ximing , Huang Ronglian , Zheng Zhe , Bian Chao , Deng Yuewen , Wang Qingheng , Wang Zhongduo , Liang Xinming , Liang Haiying , Shi Chengcheng , Zhao Xiaoxia , Sun Fengming , Hao Ruijuan , Bai Jie , Liu Jialiang , Chen Wenbin , Liang Jinlian , Liu Weiqing , Xu Zhe , Shi Qiong , Xu Xun , Zhang Guofan , Liu Xin 
Published: July 2017

Abstract
Nacre, the iridescent material found in pearls and shells of molluscs, is formed through an extraordinary process of matrix-assisted biomineralization. Despite recent advances, many aspects of the biomineralization process and its evolutionary origin remain unknown. The pearl oyster Pinctada fucata martensii is a well-known master of biomineralization, but the molecular mechanisms that underlie its production of shells and pearls are not fully understood. We sequenced the highly polymorphic genome of the pearl oyster and conducted multi-omic and biochemical studies to probe nacre formation. We identified a large set of novel proteins participating in matrix-framework formation, many in expanded families, including components similar to that found in vertebrate bones such as collagen-related VWA-containing proteins, chondroitin sulfotransferases, and regulatory elements. Considering that there are only collagen-based matrices in vertebrate bones and chitin-based matrices in most invertebrate skeletons, the presence of both chitin and elements of collagen-based matrices in nacre suggests that elements of chitin- and collagen-based matrices have deep roots and might be part of an ancient biomineralizing matrix. Our results expand the current shell matrix-framework model and provide new insights into the evolution of diverse biomineralization systems.
Operative and Perioperative Durations in O-Arm vs C-Arm Fluoroscopy for Lumbar Instrumentation
Authors: Knafo Steven , Mireau Etienne , Bennis Saad , Baussart Bertrand , Aldea Sorin , Gaillard Stephan 
Published: July 2017

Abstract

BACKGROUND
Intraoperative 3-dimensional fluoroscopy (eg, O-arm) has been shown to improve accuracy of pedicle screw placement over 2-dimensional fluoroscopy (C-arm), but its effect on surgery duration remains unclear.

OBJECTIVE
To compare the durations of operative and perioperative times between O-arm and C-arm procedures for degenerative lumbar disorders.

METHODS
We analyzed 198 patients representing 987 pedicle screws treated in a single center by 4 different surgeons between 2013 and 2015. Accuracy of pedicle screw placement was assessed using the Laine classification on postoperative CT scans. Operative and perioperative durations were prospectively reported on the procedure sheet by anesthesiologists.

RESULTS
As expected, placement of pedicle screws using O-arm navigation was overall more accurate compared to C-arm fluoroscopy (strictly intrapedicular screws: 549/663 = 82.8% vs 239/324 = 73.8%, P = .008). This benefit did not depend on surgeon individual performance (P = .17). Average operative duration per instrumented level was significantly shorter in the O-arm group (57.3 min vs 66.1 min, P = .02) but also depended on the surgeon, indication, and interbody fusion. However, only surgeon individual performance remained significantly associated with surgery duration in multivariate analysis (P < .001). Similarly, the only factor that remained significantly associated with longer perioperative durations in multivariate analysis was the indication of surgery (P < .001).

CONCLUSION
This study shows that O-arm navigation does not independently decrease operative duration, nor increases perioperative time, while improving accuracy of pedicle screw placement.
Resistance Genes in Global Crop Breeding Networks
Authors: Garrett K. A. , Andersen K. F. , Asche F. , Bowden R. L. , Forbes G. A. , Kulakow P. A. , Zhou B. 
Published: July 2017

Resistance genes are a major tool for managing crop diseases. The networks of crop breeders who exchange resistance genes and deploy them in varieties help to determine the global landscape of resistance and epidemics, an important system for maintaining food security. These networks function as a complex adaptive system, with associated strengths and vulnerabilities, and implications for policies to support resistance gene deployment strategies. Extensions of epidemic network analysis can be used to evaluate the multilayer agricultural networks that support and influence crop breeding networks. Here, we evaluate the general structure of crop breeding networks for cassava, potato, rice, and wheat. All four are clustered due to phytosanitary and intellectual property regulations, and linked through CGIAR hubs. Cassava networks primarily include public breeding groups, whereas others are more mixed. These systems must adapt to global change in climate and land use, the emergence of new diseases, and disruptive breeding technologies. Research priorities to support policy include how best to maintain both diversity and redundancy in the roles played by individual crop breeding groups (public versus private and global versus local), and how best to manage connectivity to optimize resistance gene deployment while avoiding risks to the useful life of resistance genes. [Formula: see text] Copyright © 2017 The Author(s). This is an open access article distributed under the CC BY 4.0 International license .
Fatigue in Residency Education: Understanding the Influence of Work Hours Regulations in Europe
Authors: Taylor Taryn S. , Teunissen Pim W. , Dornan Tim , Lingard Lorelei 
Published: July 2017

Purpose
Although one proposed solution to the problem of fatigued medical trainees is the implementation of work hours regulations, concerns about the effectiveness of these regulations are growing. Canada remains one of the few Western jurisdictions without legislated regulation. Recent research suggests that fatigue is a complex social construct, rather than simply a lack of sleep; thus, the authors explored how regulations and fatigue are understood in countries with established work hours frameworks to better inform other jurisdictions looking to address trainee fatigue.

Method
Using constructivist grounded theory methodology, the authors conducted individual, semistructured interviews in 2015–2016 with 13 postgraduate medical trainees from four European countries with established work hours regulations. Data collection and analysis proceeded iteratively, and the authors used a constant comparative approach to analysis.

Results
Trainees reported that they were commonly fatigued and that they violated the work hours restrictions for various reasons, including educational pursuits. Although they understood the regulations were legislated specifically to ensure safe patient care and optimize trainee well-being, they also described implicit meanings (e.g., monitoring for trainee efficiency) and unintended consequences (e.g., losing a sense of vocation).

Conclusions
Work hours regulations carry multiple, conflicting meanings for trainees that are captured by three predominant rhetorics: the rhetoric of patient safety, of well-being, and of efficiency. Tensions within each of those rhetorics reveal that managing fatigue within clinical training environments is complex. These findings suggest that straightforward solutions are unlikely to solve the problem of fatigue, assure patient safety, and improve trainee well-being.
Understanding the Multidimensional Effects of Resident Duty Hours Restrictions: A Thematic Analysis of Published Viewpoints in Surgery
Authors: Devitt Katharine S. , Kim Michael J. , Gotlib Conn Lesley , Wright Frances C. , Moulton Carol-Anne , Keshet Itay , Ahmed Najma 
Published: July 2017

Purpose
Individuals representing various surgical disciplines have expressed concerns with the impact of resident duty hours (RDH) restrictions on resident education and patient outcomes. This thematic review of published viewpoints aimed to describe the effects of these restrictions in surgery.

Method
The authors conducted a qualitative systematic review of non-research-based literature published between 2003 and 2015. Articles were included if they focused on the RDH restrictions in surgery and resident wellness, health promotion, resident safety, resident education and/or training, patient safety, medical errors, and/or heterogeneity regarding training or disciplines. A thematic analysis approach guided data extraction. Contextual data were abstracted from the included articles to aid in framing the identified themes.

Results
Of 1,482 identified articles, 214 were included in the review. Most were from authors in the United States (144; 67%) and focused on the 80-hour workweek (164; 77%). The emerging themes were organized into three overarching categories: (1) impact of the RDH restrictions, (2) surgery has its own unique culture, and (3) strategies going forward. Published opinions suggested that RDH restrictions alone are insufficient to achieve the desired outcomes and that careful consideration of the surgical training model is needed to maintain the integrity of educational outcomes.

Conclusions
Opinions from the surgical community highlight the complexity of issues surrounding the RDH restrictions and suggest that recent changes are not achieving all the desired outcomes and have resulted in unintended outcomes. From the perceptions of the various stakeholders in surgical education studied, areas for new policies were identified.
Treatment of Facial Acne Scarring With Fractional Carbon Dioxide Laser in Asians, a Retrospective Analysis of Efficacy and Complications
Authors: Ochi Harumi , Tan Lixian , Tan Wee Ping , Goh Chee Leok 
Published: July 2017

BACKGROUND
Fractional carbon dioxide (CO2) laser resurfacing unites the idea of fractional photothermolysis with an ablative 10,600-nm wavelength. This technology permits effective treatment of acne scarring, with shorter recovery and a decreased side effect profile as compared to traditional CO2 laser resurfacing.

OBJECTIVE
The aims of this study were to study the efficacy and safety of fractional CO2 laser for acne scars in Asian patients.

METHODS
This was a retrospective study of all patients treated with the fractional CO2 laser for facial acne scarring between January 2, 2008, and December 31, 2010, at the National Skin Centre, Singapore. Data reviewed included sex, age, and severity of acne, type of scarring, previous treatment history, frequency of treatments, adverse events, and efficacy.

RESULTS
Two hundred and ten fractional CO2 laser treatments for facial acne scars were performed on 107 patients (65 men and 42 women, Fitzpatrick skin Types II to V) during the study period. Sixteen of 107 patients experienced (15.0%) adverse events. The adverse events include hyperpigmentation (6.4%), blistering (4.0%), crusting (2.9%), aggravation of inflammatory acne lesions (1.7%), and scarring (0.6%). There were no reported side effects of hypopigmentation, bacterial or viral infection. Follow-up results after final laser treatment showed that 66.4% of patients reported Grade 1 skin texture improvement, that is, <25% (n = 71); 30.0% had Grade 2 improvement, that is, 25% to 50% improvement (n = 31); 3.7% had Grade 3 improvement, that is, 51% to 75% improvement (n = 4); and 0.9% had Grade 4 improvement, that is, >75% improvement (n = 1).

CONCLUSION
The study demonstrated the efficacy and safety of a fractional CO2 laser in the treatment of acne scars in Asian. Future studies are required to establish optimum treatment parameters and achieve better clinical results.
Reliable and Easy-To-Use Liquid Chromatography–Tandem Mass Spectrometry Method for Simultaneous Analysis of Fluconazole, Isavuconazole, Itraconazole, Hydroxy-Itraconazole, Posaconazole, and Voriconazole in Human Plasma and Serum
Authors: Müller Carsten , Gehlen David , Blaich Cornelia , Prozeller Domenik , Liss Blasius , Streichert Thomas , Wiesen Martin H. J. 
Published: July 2017

Background:
A fast and easy-to-use liquid chromatography-tandem mass spectrometry method for the determination and quantification of 6 triazoles [fluconazole (FLZ), isavuconazole (ISZ), itraconazole (ITZ), hydroxy-itraconazole (OH-ITZ), posaconazole (PSZ), and voriconazole (VRZ)] in human plasma and serum was developed and validated for therapeutic drug monitoring.

Methods:
Sample preparation was based on protein precipitation with acetonitrile and subsequent centrifugation. Isotope-labeled analogues for each analyte were used as internal standards. Chromatographic separation was achieved using a 50 × 2.1 mm, 1.9 μm polar Hypersil Gold C18 column and mobile phase consisting of 0.1% formic acid/acetonitrile (45%/55%, vol/vol) at a flow rate of 340 μL/min. The triazoles were simultaneously detected using a triple-stage quadrupole mass spectrometer operated in selected reaction monitoring mode with positive heated electrospray ionization within a single runtime of t = 3.00 minutes.

Results:
Linearity of all azole concentration ranges was verified by the Mandel test and demonstrated for all azoles. All calibration curves were linear and fitted using least squares regression with a weighting factor of the reciprocal concentration. Limits of detection (μg/L/L) were FLZ, 9.3; ISZ, 0.3; ITZ, 0.6; OH-ITZ, 8.6; PSZ, 3.4; and VRZ, 2.1. The lower limits of quantitation (μg/L/liter) were FLZ, 28.3; ISZ, 1.0; ITZ, 1.7; OH-ITZ, 26.2; PSZ, 10.3; and VRZ, 6.3. Intraday and interday precisions ranged from 0.6% to 6.6% for all azoles. Intraday and interday accuracies (%bias) of all analytes were within 10.5%. In addition, we report on a 29-year-old white woman (94 kg body weight) with a history of acute myeloid leukemia who underwent stem cell transplantation. Because of diagnosis of aspergillus pneumonia, antifungal pharmacotherapy was initiated with different application modes and dosages of ISZ, and plasma concentrations were monitored over a time period of 6 months.

Conclusions:
A precise and highly sensitive liquid chromatography-tandem mass spectrometry method was developed that enables quantification of triazoles in plasma and serum matrix across therapeutically relevant concentration ranges. It was successfully implemented in our therapeutic drug monitoring routine service and is suitable for routine monitoring of antifungal therapy and in severely ill patients.