bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oscillatory features of German–English sentence processing: Evidence from an EEG study
Authors: Zheng Yuxuan , Kirk Ian , Waldie Karen 
Published: October 2024

Aims and objectives: In this study, we investigated the neural oscillatory patterns occurring during sentence-level overt bilingual processing tasks on 46 German–English bilinguals with the intention of finding out if there were task-specific oscillations for this language pair. Methodology: Four tasks, including Language 2 (L2) listening, Language 1 (L1) speaking, L2 shadowing (i.e., repeating a segment of an utterance), and backward interpreting (i.e., orally translating L2 sentences to L1), were implemented with the technique of electroencephalography (EEG). Data and analysis: Data included demographic indices, neural oscillation metrics, and oral production scores from participants. Static spectral analysis, time–frequency analysis, principal components analysis, cross-frequency coupling, and inferential statistics were applied to the data. Findings: The sensory task and articulatory tasks differed greatly in the delta–theta band and the beta–gamma band in terms of time–frequency dynamics. Analyses also revealed variations in a frontal/prefrontal theta component and a distinct gamma component across the four tasks. Moreover, we found a right fronto-temporal theta–gamma coupling unique to backward interpreting. Originality: The task-wise comparison experiment paradigm has rarely been implemented in neuroimaging research on language, especially so in EEG research on bilingualism. Significance: The findings provide novel insights for the understanding of language conversion mechanism and may benefit the training of professional interpreters.
Patient-reported treatment satisfaction in essential tremor: levels of satisfaction and predictors of satisfaction
Authors: Varghese Anjali , Berry Diane S. , Ghanem Ali , Hernandez Nora C. , Louis Elan D. 
Published: October 2024

Background: Although managing symptoms is paramount for both essential tremor (ET) patients and their healthcare providers, studies of treatment satisfaction are surprisingly lacking. Objectives: We evaluated the satisfaction of patients who used a range of treatments and assessed the relation of a wide array of factors to satisfaction. Methods: One hundred four ET participants (age = 74.5 ± 10.2 years) completed a battery of self-report items. These included demographic information, measures of tremor and clinical history, psychological state, current ET treatment, and a series of questions about satisfaction with treatment. Results: Analyses of responses to the four current treatment satisfaction questions revealed that the proportion of participants who were satisfied ranged from 35.0% to 57.3% (i.e., approximately 1/3 to 1/2); conversely, the proportion who were dissatisfied ranged from 9.2% to 37.0%. The remainder were neutral. Higher satisfaction levels were observed in participants who were included in treatment selection and who had undergone deep brain stimulation surgery, p’s < 0.05. Lower levels of satisfaction were found in participants with a negative psychological state, higher self-rated tremor severity, head/voice/jaw tremors, and more severe physical side effects; and who used botulinum toxin therapy, p’s < 0.05. Conclusion: Between 1/3 and 1/2 of patients were satisfied with their treatment, whereas up to 1/3 were dissatisfied. In this initial exploration of correlates of treatment satisfaction in ET patients, we identified a number of associations between satisfaction and clinical, psychological and treatment variables. Additional research is warranted to further explore the nature of these relations over time.
Comprendre l’adoption et la continuation de l’utilisation du diaphragme Caya au Bénin : une étude à méthodes mixtes
Authors: Zinsou Cyprien , Guedegbe Ghyslain , Angel Alexandra , Bouanchaud Paul , Jackson Ashley , Kikissagbe Isidore , Brogaard Beth 
Published: October 2024

Résumé Le diaphragme Caya, de taille unique, est une méthode de contraception efficace dans multiples contextes. Pourtant, la recherche sur son acceptabilité, utilisation, et continuation en Afrique de l’Ouest francophone reste limitée. Ce projet pilote a introduit Caya à Cotonou et Bohicon, Bénin pour mieux comprendre comment Caya est utilisé. 225 adoptantes ont participé à une enquête, six mois après avoir choisi la méthode. 30 adoptantes, 15 hommes de la communauté et 15 prestataires ont participé à des entretiens approfondis. L’étude a révélé que les adoptantes choisissent la méthode parce qu’elle était non hormonale et ne provoque pas d’effets secondaires. Six mois après avoir adopté Caya, 76,4 % des adoptantes continuaient à l’utiliser ; celles moins instruites et avec 1 enfant ou plus, étaient plus susceptibles de continuer à utiliser Caya. Cela indique que dans ce contexte, Caya est une méthode acceptable qui ajouterait de la valeur aux autres méthodes contraceptives.
Crocin Inhibited Epithelial-Mesenchymal Transition in Renal Tubular Epithelial Cells to Treat Diabetic Nephropathy Through Improving AMPK/mTOR-Mediated Autophagy
Authors: Su Jinhao , Chen Wei , Zhang Hui , Li Hanzhou , Pan Baochao , Ma Ziang , Wang Yuansong , Cui Huantian , Lv Shuquan 
Published: October 2024

Objectives Diabetic nephropathy (DN), a severe microvascular complication of diabetes mellitus, is a leading cause of end-stage renal disease. Crocin (CRO), an active ingredient extracted from Crocus sativus and Gardenia jasminoides, has multiple bioactivities such as anti-oxidative, anti-inflammatory, anti-tumor, and anti-depressive activities. However, the potential effects and mechanisms of CRO in the treatment of DN are still unclear. Methods In this study, we aimed to assess the efficacy of CRO in treating DN using in vivo and in vitro experiments, and intensively investigate the potential therapeutic mechanisms of CRO against DN based on the inhibition of epithelial-mesenchymal transition (EMT) by inducing adenosine monophosphate-activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)-mediated autophagy. Results The results showed that CRO had a therapeutic effect and anti-EMT effect in kidney of DN mice. CRO also moderated AMPK/mTOR pathway and improved autophagy in kidney of DN mice. In high glucose (HG)-induced tubular epithelial cell EMT model, CRO inhibited EMT, moderated AMPK/mTOR pathway and improved autophagy. AMPK inhibitor abolished the above effects of CRO on tubular epithelial cells. Conclusion CRO exhibited considerably therapeutic and anti-EMT effects on DN both in vivo and in vitro, these may be associated with restoring autophagy through regulating AMPK/mTOR pathway.
Stroke survivors’ telemedicine experiences during the COVID-19 pandemic: A phenomenological investigation
Authors: Kimmel Barbara , Walder Annette , Ovalle Anette , Venkatasubba Rao Chethan P , Savitz Sean I , Goldberg Mark , Warach Steven , Cruz-Flores Salvador , Olson DaiWai M , Anderson Jane A 
Published: October 2024

Purpose This study aimed to describe stroke survivors’ experiences receiving telemedicine visits at the Lone Star Stroke Consortium during the COVID-19 pandemic. Materials and Methods A qualitative descriptive phenomenological design was applied to gather patients’ telemedicine experiences through in-depth interviews, using a study guide. Audio-recorded interviews were conducted via ZOOM and transcribed verbatim. Two independent reviewers used the Giorgi descriptive method to analyze the data and search for the essence of stroke survivors’ follow-up telemedicine experiences during the COVID-19 pandemic. Results Fifteen underserved patients were recruited: mean age, 51.8 (15.7), and 9 (60%) females. Three themes emerged: (1) vivid memory of the stroke acute phase, (2) poststroke care experiences, and (3) perceived telemedicine experiences. Conclusions The phenomenon of follow-up telemedicine visits during COVID-19 pandemic, as experienced by the stroke survivors, was positive. It showed patients’ improved care access for poststroke visits. Telemedicine was satisfactory, except where the full medical exam was needed. Study findings highlight the individual approach was important, as well as the need for reliable internet and training to improve patients’ technological skills. A hybrid approach for post-pandemic follow-up visits (in-person and telemedicine) was recommended by stroke survivors. These findings suggest that telemedicine is feasible and effective for poststroke care. Additional strategies are needed to improve future telemedicine integration into the continuum of care.
Effectiveness of digital health interventions to increase cardiorespiratory fitness: A systematic review and meta-analysis
Authors: Rowland Sheri , Bach Christina , Simon Krystyna , Westmark Danielle M , Sperling Edie 
Published: October 2024

Background Interventions using commercial digital health tools do favorably affect health outcomes. However, the effect of digital tools on cardiorespiratory fitness, a more novel indicator cardiovascular risk, is unclear. Purpose Synthesize the digital health intervention literature and answer the following question: What is the effect of interventions using mobile health apps, wearable activity trackers, and/or text messaging on cardiorespiratory fitness? Methods A systematic review and a meta-analysis (PROSPERO CRD42023423925) were conducted to evaluate the immediate digital health intervention effect on adult cardiorespiratory fitness. In March 2023, a search of databases Embase, MEDLINE, CINHAL, and Cochrane Library was completed. Studies were included if the intervention used a mobile health app, text messaging, and/or activity tracker. Studies were excluded if an objective measure of fitness was not used; the sample included children; the setting was hospital-based; and the digital health technology was only used for data collection or described as virtual reality. Using a random-effects model, two separate meta-analyses were completed: one for single-group studies and one for multi-group studies. Standardized mean difference effect sizes (Cohen's d) were calculated. Study quality was evaluated with the Cochrane Risk of Bias tool and ROBINS-I tool. Results Fifty-three studies (3657 individuals) with pre-post designs (12 single-group, 41 multi-group) were included. Most studies targeted participants with a specific chronic health condition. Digital health interventions in the single-group studies had a moderate-to-large effect size ( d = 0.62, 95% confidence interval ( CI) [0.41–0.84], p < 0.001), and multi-group studies had small-to-moderate effect size ( d = 0.38, 95% CI 0.21–0.55, p < 0.001). Significant heterogeneity of effects was observed in both the single-group and multi-group studies. Conclusions Interventions using text messaging, a mobile app, or activity tracker alone or in combination are effective in improving cardiorespiratory fitness in adults, particularly for those with a chronic health condition.
District health information system 2 data utilization among health professionals in Amara region private hospitals, Ethiopia
Authors: Mesele Abraraw Gebre , Birhanu Abreham Yeneneh , Shiferaw Atsede Mazengia , Baykemagn Nebebe Demis 
Published: October 2024

Background Globally, health information systems have been improved by District Health Information System Version 2 (DHIS2), which promotes consistency and integrity in collecting data, processing, and utilization. This success has been attributed to its user-friendly interface and incorporation of advanced data analysis and validation features. Objective This study aimed to assess DHIS2 data utilization among health professionals working at private hospitals in the Amara region. Methods An Institution-based cross-sectional study design was conducted from 9 May to 30 June 2022. A simple random sampling technique was used to select participants, with a total of 395 health professionals participating. Data was collected using a self-administered paper-based questionnaire. Data entry was performed using the Kobo Collect tool, and data analysis was conducted using STATA version 14.0. Bivariable and multivariable logistic regression analyses were used and p < .05 with a 95% CI was considered to measure statistically significant variables. Result Out of 395 participants, about 37.72% of the participants had good DHIS2 data utilization. Had good data analysis skills (adjusted odds ratio (AOR) = 6.5, 95% CI [3.1–13.8]), regular supportive supervision and feedback (AOR = 5.2, 95% CI [2.8–9.5]), monthly salary > 5000 ETB (AOR = 2.0, 95% CI [1.1–3.7]), ease of use (AOR = 5.4, 95% CI [2.8–10.2]), and district health information system training (AOR = 4.2, 95% CI [2.2–7.3]) were enabling factors for utilization of DHIS2 data. Conclusion Private healthcare providers had limited utilization of DHIS2 data. It is highly recommended to provide DHIS2 training, supervision, and feedback focused on private health facilities. Additionally, enhancing data analysis skills and prioritizing ease of use are crucial to improving DHIS2 data utilization.
Utilizing deep learning models for ternary classification in COVID-19 infodemic detection
Authors: Luo Jia , El Baz Didier , Shi Lei 
Published: October 2024

Objective To address the complexities of distinguishing truth from falsehood in the context of the COVID-19 infodemic, this paper focuses on utilizing deep learning models for infodemic ternary classification detection. Methods Eight commonly used deep learning models are employed to categorize collected records as true, false, or uncertain. These models include fastText, three models based on recurrent neural networks, two models based on convolutional neural networks, and two transformer-based models. Results Precision, recall, and F1-score metrics for each category, along with overall accuracy, are presented to establish benchmark results. Additionally, a comprehensive analysis of the confusion matrix is conducted to provide insights into the models’ performance. Conclusion Given the limited availability of infodemic records and the relatively modest size of the two tested data sets, models with pretrained embeddings or simpler architectures tend to outperform their more complex counterparts. This highlights the potential efficiency of pretrained or simpler models for ternary classification in COVID-19 infodemic detection and underscores the need for further research in this area.
e-Health literacy and online health information utilization among Jordanians: A population-based study
Authors: Al-Ruzzieh Majeda A. , Al-Helih Yahia M. , Al-Soud Zaid 
Published: October 2024

Background The internet has become an essential part of empowering people to access health-related information. Huge amounts of health-related information are available online, but few people have the skills to assess its validity and reliability. Accordingly, the concept of ehealth literacy competencies emerged to measure the skills necessary to validate such information. As a result, the purpose of this study was to assess Jordanian people’s e-health literacy, online health information utilization, and associated factors. Methods This population-based cross-sectional study was conducted from March to December 2023. Results Results: The study found that participants rated their e-health literacy at 28.94 out of 40, indicating a sufficient level of health literacy, and their online health information utilization at 39.62, indicating a high level of engagement with online health resources. Furthermore, it is revealed that e-health literacy is associated with gender and geographic region, whereas online health information utilization is associated only with chronic disease. Conclusion In Jordan, there is a balance between traditional and online health information use. While healthcare providers and primary health centers are the main sources of information, Jordanians show a sufficient level of e-health literacy, with females and the capital region exhibiting higher levels. Furthermore, Jordanians were more likely to use online health information. Nevertheless, it is crucial to work on improving internet platforms to enhance the quality of online health-related information.
Patient-initiated video consultations: A qualitative study on reasons for patient-booking in Danish general practice
Authors: Van den Heuvel Johannes , Assing Hvidt Elisabeth , Dahl-Larsen Rasmus , Thomsen Janus Laust , Hoffmann Merrild Camilla 
Published: October 2024

Objective This qualitative study explores when and why patients book video consultations through an online booking platform within the context of Danish general practice and how the technology affects patients’ use of this consultation type. Methods We conducted thirteen semi-structured interviews with patients from the same general practice who were experienced users of video consultations scheduled through the clinic's online booking platform. Interviews were analysed using thematic analysis and drawing on actor-network theory and Bruno Latour's concept of technical mediation as an analytical framework. Results We introduce the concept of “hybrid patients,” highlighting how values tied to video consultation that motivates patients to book them emerge through technical mediation in the network between patients, general practitioners (GPs) or practice staff, and the video technology. We identified three emerging values: efficiency, control and diminished presence. Video consultation affords efficient consultations that save patients’ time. It mediates patients’ sense of control when they experience certainty concerning their health issues. Video consultation mediates diminished presence that increases relational distance. However, it simultaneously allows for efficiency and emotional distance between patients and their GP, and between patients and their health issues. Conclusions When initiating the use of video consultation, the patient plays an active and conscious role in adjusting to the mediated values (efficiency, control and diminished presence) linked to this form of consultation. These emerging values are context-specific, and patients employ them based on their individual requirements. Patients trust their GPs to prevent severe or vulnerable topics from being discussed in a video consultation.
Cesarian sections in women with multiple sclerosis: A Canadian prospective pregnancy study
Authors: Sadovnick Dessa , Criscuoli Maria , Yee Irene , Carruthers Robert , Devonshire Virginia , Smyth Penelope , Krysko Kristen M 
Published: October 2024

BackgroundAn increasing number of women with multiple sclerosis (wMS) are considering pregnancy. Prior studies suggest increased rate of elective cesarian sections (C-sections) in wMS.MethodsThe Canadian Multiple Sclerosis Pregnancy Study (CANPREG-MS) is a prospective study on pregnant wMS. This report shows comparisons between (i) CANPREG-MS wMS delivered by C-section and the general population and (ii) C-section and vaginal deliveries in this study cohort.ResultsCANPREG-MS has resulted in 170 deliveries with 63 by C-section. The proportion with C-sections in CANPREG-MS (37.1%) was significantly higher than that for the Canadian population (28%) ( p = .0085). The majority (66.7%) of C-sections were not planned, and typically were performed for obstetrical indications. C-sections were performed at an earlier gestational age than vaginal deliveries, although birthweight did not differ by mode of delivery in wMS. MS relapses (3.2%) and pseudo-relapses (3.2%) were rare in the first month after C-section deliveries, regardless of disease modifying therapy decisions during gestation and postpartum.ConclusionsC-sections were more common in wMS than the general population, but few were because of maternal MS. CANPREG-MS provides informative data for pregnancies in wMS with well-managed and relatively mild disease. This information is helpful to obstetrical and MS healthcare providers.
Biomechanical Comparison of Suture-Relay All-Suture Anchors and Conventional Suture Anchors for Posterior Medial Meniscus Root Repair in Porcine Models
Authors: Saengpetch Nadhaporn , Prasitmeeboon Napat , Janyawongchot Tanapol , Aroonjarattham Panya , Somtua Chompunut , Thamyongkit Sorawut 
Published: October 2024

Background: Posterior medial meniscus root (PMMR) tears (PMMRTs) can be repaired using various techniques to promote healing. However, the biomechanical properties of suture-relay all-suture anchor (ASA) versus conventional suture anchor (CSA) and loop-locking transtibial pullout (TTP) have not been well established. Purpose: To compare the biomechanical properties of PMMR repairs using suture-relay ASA, CSA, and loop-locking TTP. Study Design: Controlled laboratory study. Methods: A total of 33 fresh-frozen porcine knee joints with intact medial menisci were randomly divided into 3 groups, with 11 specimens in each group: ASA, CSA, and TTP. The study involved cyclic loading, with displacement measurements taken after 100, 500, and 1000 cycles. Subsequently, the specimens were loaded until clinical failure (defined as 3-mm displacement) and then to ultimate failure of the construct, with data recorded for displacement after cyclic loading, load to 3-mm displacement, and ultimate load to failure. Results: After 1000 cyclic loadings, the suture-relay ASA group showed considerably less displacement than the loop-locking TTP group (1.8 ± 0.7 mm vs 2.9 ± 0.3 mm; P < .001), but the displacements did not differ considerably between the suture-relay ASA and CSA groups (2.2 ± 0.9 mm; P > .05). The mean loads to clinical failure were significantly greater in the suture-relay ASA and CSA groups (61.3 ± 6.5 and 57.5 ± 9.7 N, respectively) than in the loop-locking TTP group (38.3 ± 9.4 N; P < .05). The ultimate load to failure was significantly greater in the suture-relay ASA group than in the loop-locking TTP group (153 ± 55.1 N vs 102 ± 12.9 N; P < .05). All specimens in the loop-locking TTP group failed by suture elongation mode, whereas only 2 specimens (18%) in the suture-relay ASA group and 5 specimens (45%) in the CSA group failed by suture elongation. Nine specimens (82%) in the suture-relay ASA group and 6 specimens (55%) in the CSA group failed due to suture cutout through the meniscal tissue. Conclusion: The biomechanical properties after PMMR repair did not statistically differ between the suture-relay ASA and CSA groups. The suture-relay ASA technique had a higher load to failure than the loop-locking TTP technique. Clinical Relevance: The suture-relay ASA technique is a promising option for the repair of PMMRTs; its repairing strength is also comparable to that of the CSA technique. Notably, the suture-relay ASA technique can be utilized without establishing a posteromedial portal, resulting in decreased procedure time and mitigating challenges associated with working from the posterior aspect of the knee.