bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diode Lasers Enable Diverse Therapeutic Applications
Authors: Neukum Jörg , Schulze Matthias 
Published: December 2017

AbstractLasers are widely used throughout medicine, from diagnostic imaging and clinical testing, to surgical treatments and the latest aesthetic procedures. For therapeutic medical procedures, in particular, diode lasers have now become the dominant laser type in use. This is because these workhorse devices provide lower cost of ownership, a wider choice of output wavelength and power, compact rugged packaging, and superior (semiconductor) reliability as compared to other laser types. In this article, we briefly examine the main features and advantages of typical diode laser types, and then survey some of the leading therapeutic applications that currently rely on them.
Detecting Cardiac Infarction Risk Reliably Using Fast Laser Pulses
Authors: Wu Min 
Published: December 2017

AbstractPhotoacoustic imaging based on laser pulses is a promising method for clinical detection of vulnerable arterial plaque that is a potential trigger for cardiac infarction. With a custom‐designed combination of pulse laser and OPO (optical parametric oscillator), Elforlight and AMS Technologies contribute to substantial acceleration of this imaging method's intravascular application.
Development of cellulose nanocrystal‐reinforced polylactide: A comparative study on different preparation methods
Authors: Bagheriasl Davood , Safdari Fatemeh , Carreau Pierre J. , Dubois Charles , Riedl Bernard 
Published: December 2017

A masterbatch of polylactide (PLA) containing cellulose nanocrystals (CNCs) prepared via a solution‐cast method was further diluted with neat PLA in the melt state using either a twin‐screw extruder or an internal batch mixer to reach a final CNC content of 4 wt%. For the sake of comparison, a direct melt mixing method was employed to prepare PLA–CNC composites. Then, the efficiency of the preparation methods was assessed by comparing the morphological, rheological and thermomechanical properties of the compounded samples. Scanning electron microscopy showed the disappearance of large agglomerates when using the PLA–CNC masterbatch. Transmission electron microscopy revealed the existence of well‐dispersed CNCs within the PLA matrix at a nanoscale for masterbatch‐based nanocomposites. The rheological properties of the nanocomposites containing the PLA–CNC masterbatch were significantly increased for both steady and small‐amplitude oscillatory shear flow fields, compared to the composites prepared via direct melt mixing. In addition, the masterbatch‐based nanocomposites exhibited pronounced overshoots in the transient start‐up viscosity. The crystalline content of the PLA in the nanocomposites and the crystallization temperature increased when the CNCs were well dispersed, which showed the nucleating effect of the CNCs. In dynamic mechanical thermal analysis, the storage modulus of the nanocomposites increased up to 41 and 128% in the glassy and rubbery regions, respectively. These results show that hydrophilic CNCs can be well dispersed and reinforce PLA using efficient preparation methods. POLYM. COMPOS., 40:E342–E349, 2019. © 2017 Society of Plastics Engineers
Behavior Bingo: The effects of a culturally relevant group contingency intervention for students with EBD
Authors: Collins Tai A. , Hawkins Renee O. , Flowers Emily M. , Kalra Hilary D. , Richard Jessie , Haas Lauren E. 
Published: December 2017

AbstractStudents with emotional and behavioral disorders (EBD) have difficulty with academic engagement during independent seatwork tasks. The goal of the current study was to evaluate the effectiveness of Behavior Bingo, a novel interdependent group contingency intervention, on the academic engagement, off‐task, and disruptive behavior of students with EBD during independent seatwork in an urban alternative high school setting. During the intervention, the class collaborated to fill in a posted Bingo board contingent on demonstrating appropriate behavior. Using an ABAB withdrawal design in two classrooms, the Behavior Bingo intervention showed promise as a feasible and effective classroom management intervention. Given the urban setting and diverse sample of participants, implications for culturally relevant and responsive intervention are discussed, including the role of peers in culturally responsive intervention, the use of randomization and uncertainty, preference assessment, and engaging intervention components.
Breast and gynecological cancer patients' risk factors associated with biopsychosocial problem‐related distress
Authors: Bergerot Cristiane Decat , Clark Karen Lynn , Obenchain Richard , Philip Errol J. , Loscalzo Matthew 
Published: December 2017

AbstractObjectivesInequalities exist between breast and gynecological cancer patients' experiences, leading to high levels of distress throughout the cancer journey. The present study aims to identify differences in source of biopsychosocial problem‐related distress between women diagnosed with breast or gynecological cancers.MethodsFrom 2009 to 2016, women with breast (n = 2111) and gynecological (n = 641) cancers were screened using the core items of the instrument You, Your Family, and City of Hope are a Team. This is a touch screen–based instrument that assess problem‐related distress due to physical, practical, functional, emotional, and other problems and identifies types of assistance requested. Data were analyzed using the linear regression model.ResultsA significant difference in overall biopsychosocial problems rated as high distress was found between breast (M = 5.0) and gynecological (M = 6.2) cancer patients (P < .001). Gynecological cancer patients endorsed a greater number of problems to talk with a member of the team (alone or with written information), while both cancer groups requested written information equally. Gynecological cancer was associated with higher physical, functional, emotional, and total distress. Younger patients, non‐Asian, and those with lower education and lower household income also reported greater distress.ConclusionsGynecological cancer patients represent a high‐risk group, reporting greater problem‐related distress and higher levels of requested assistance. Age, education, race/ethnicity, and income were found to be potential risk factors. Findings highlight the importance of considering characteristics and special needs related to specific types of cancer to assist in the effective treatment of distress throughout the continuum of care.
Doping of Fullerene‐Like MoS2 Nanoparticles with Minute Amounts of Niobium
Authors: Rosentsveig Rita , Yadgarov Lena , (Isai) Feldman Yishay , Shilstein Sana , Popovitz‐Biro Ronit , Visic Bojana , Sedova Anastasiya , Cohen Sidney R. , Li Yuanyuan , Frenkel Anatoly I. , Tenne Reshef 
Published: December 2017

AbstractInorganic fullerene‐like closed‐cage nanoparticles of MoS2 and WS2 (IF‐MoS2; IF‐WS2), are synthesized in substantial amounts and their properties are widely studied. Their superior tribological properties led to large scale commercial applications as solid lubricants in numerous products and technologies. Doping of these nanoparticles can be used to tune their physical properties. In the current work, niobium (Nb) doping of the nanoparticles is accomplished to an unprecedented low level (≤0.1 at%), which allows controlling the work function and the band gap. The Nb contributes a positive charge, which partially compensates the negative surface charge induced by the intrinsic defects (sulfur vacancies). The energy diagram and position of the Fermi level on the nanoparticles surface is determined by Kelvin probe microscopy and optical measurements. Some potential applications of these nanoparticles are briefly discussed.
Synergistic Effect of Photothermal Therapy and Chemotherapy Using Camptothecin‐Conjugated Gold Nanorods
Authors: Yang Soojung , Palanikumar L. , Jeong Sundo , Kim Kibeom , Lee Jungmin , Jeoung Eunhee , Kim Chaekyu , Ryu Ja‐Hyoung , Park Myoung‐Hwan 
Published: December 2017

AbstractA combinatorial treatment comprising thermal therapy and chemotherapy offers synergistic effects by inducing localized heat to targeted tumor sites and simultaneously delivering anticancer drugs to minimize systemic side effects and enhance the cytotoxic effect. In this study, a novel platform is developed for combining photothermal therapy and chemotherapy using drug‐conjugated gold nanorods (GNRs). Camptothecin (CPT), a model anticancer drug, is chemically conjugated onto GNRs through hydrolytic ester bonding. Upon near‐infrared (NIR) irradiation, localized heat from GNRs in target areas starts to destroy tissues and cells via photothermal therapy, and the elevated temperature accelerates hydrolysis of ester linkage, rapidly releasing drugs for chemotherapy. This combined NIR triggered thermal therapy and chemotherapy with CPT‐functionalized GNRs (CPT‐GNRs) presents a synergistic effect that has high efficacy in in vitro tests, thus providing a robust platform for efficient cancer treatments.
Detection of the Human Anti‐ActRII Antibody Bimagrumab in Serum by Means of Affinity Purification, Tryptic Digestion, and LC‐HRMS
Authors: Walpurgis Katja , Thomas Andreas , Dellanna Frank , Schänzer Wilhelm , Thevis Mario 
Published: December 2017

PurposeInhibitors of the ActRII signaling pathways represent promising therapeutics for the treatment of muscular diseases, but also pose risks as performance‐enhancing agents in sports. Bimagrumab is a human anti‐ActRII antibody which was found to increase muscle mass and function by blocking ActRII signaling. As it has considerable potential for being misused as doping agent in sports, the aim of this study was to develop a mass spectrometric detection assay for doping control serum samples.Experimental designWithin this study, a detection method for Bimagrumab in human serum was developed, which combines ammonium sulfate precipitation and affinity purification with proteolytic digestion and LC‐HRMS. To facilitate the unambiguous identification of the diagnostic peptides, an orthogonal IM separation was additionally performed.ResultsThe assay was successfully validated and the analysis of clinical samples demonstrated its fitness for purpose for an application in routine doping control analysis.Conclusions and clinical relevanceAlthough no myostatin inhibitors have obtained clinical approval yet, the proactive development of detection methods for emerging doping agents represents a key aspect of preventive doping research. The presented approach will expand the range of available tests for novel protein therapeutics and can readily be modified to include further target analytes.
Metabolite profiling and isolation of biologically active compounds from Scadoxus puniceus, a highly traded South African medicinal plant
Authors: Naidoo Devashan , Slavětínská Lenka Poštová , Aremu Adeyemi O. , Gruz Jiri , Biba Ondrej , Doležal Karel , Van Staden Johannes , Finnie Jeffrey F. 
Published: December 2017

Scadoxus puniceus (Amaryllidaceae), a medicinal plant of high value in South Africa, is used as a component of a traditional herbal tonic prescribed to treat several ailments. Ultra‐high performance liquid chromatography–tandem mass spectrometry quantified the phenolic compounds in different organs of S. puniceus. Gravity column chromatography was used to separate fractions and active compounds. The structure of these compounds was determined using 1D and 2D nuclear magnetic resonance and mass spectroscopic techniques. A microplate technique was used to determine the acetylcholinesterase inhibitory activity of the pure compounds. Metabolite profiling revealed a greater profusion of hydroxycinnamic acids (69.5%), as opposed to hydroxybenzoic acids (30.5%). Chlorogenic acid was the most abundant (49.6% of hydroxycinnamic acids) compound. In addition to chlorogenic acid, the study is the first to report the presence of sinapic, gallic, and m‐hydroxybenzoic acids in the Amaryllidaceae. Chromatographic separation of S. puniceus led to the isolation of haemanthamine (1), haemanthidine (2), and a rare chlorinated amide, metolachlor (3), the natural occurrence of which is described for the first time. Haemanthamine, haemanthidine, and metolachlor displayed strong acetylcholinesterase inhibitory activity (IC50; 23.1, 23.7, and 11.5 μM, respectively). These results substantiate the frequent use of S. puniceus as a medicinal plant and hold much promise for further pharmaceutical development.
Managing the tensions between exploration and exploitation: The role of time
Authors: Mathias Blake D. , Mckenny Aaron F. , Crook T. Russell 
Published: December 2017

Research SummaryOrganizational ambidexterity reflects an organization's capacity to balance the pursuit of exploration and exploitation. Although the role of time has been central to ambidexterity theory, studies incorporate time in myriad ways, leading to an unclear understanding of how different aspects of time influence the relationship between ambidexterity and performance. We conduct a meta‐analysis of 52 studies involving more than 13,000 organizational observations and find that the performance effects of ambidexterity are stronger among older firms and firms that simultaneously balance exploration and exploitation throughout the organization. However, we also find that the ambidexterity‐performance relationship is weaker when ambidexterity is measured dynamically and when linked to long‐term performance.Managerial SummaryAlthough academics have long espoused that firms should balance investments between exploration and exploitation activities because doing so improves firm performance, little research has explicitly modeled the role of time in this balance. We combined all known evidence to assess the role of time on balancing and performance. The two key takeaways for entrepreneurs and managers are that, on average, “balancing” leads to stronger financial performance for (a) older organizations and (b) firms that simultaneously balance activities throughout the organization. Managers may not see the strongest benefits from such a balance when attempting to influence long‐term performance or when this balance occurs at different times or places inside the organization.
Microwave‐Assisted Synthesis of Some Hybrid Molecules Derived from Morpholine and Investigation of Their Antimicrobial Activities
Authors: Cebeci Yıldız Uygun , Ozdemir Serap Basoglu , Ceylan Sule , Bayrak Hacer , Demirbas Ahmet , Alpay‐Karaoglu Sengul , Demirbas Neslihan 
Published: December 2017

Abstract2H‐1,2,4‐triazol‐3(4H)‐one compound was obtained starting from 4‐(2‐fluoro‐4‐nitrophenyl)morpholine via several steps. Then, these compounds were converted to the corresponding fluoroquinolone hybrids via one pot three component Mannich reaction. Moreover, the synthesis of eleven compounds, which can be considered as conazole analogues, was performed starting from 1,2,4‐triazole‐3‐one compounds via three steps by either conventional or microwave mediated conditions. The effect of different solvents and microwave power on microwave prompted reactions was examined as well.
Pd Nanoparticles‐Supported Carbon Nanotube‐Encapsulated NiO/MgO Composite as an Enhanced Electrocatalyst for Ethanol Electrooxidation in Alkaline Medium
Authors: Mahendiran Chinnathambi , Rajesh Dhanushkotti , Maiyalagan Thandavarayan , Prasanna Kadirvelayutham 
Published: December 2017

AbstractIn this work, an easy method is developed to prepare well‐dispersed palladium nanoparticles into the carbon nanotube (CNT) encapsulated NiO/MgO nanocomposite by the chemical reduction method. CNT encapsulated NiO/MgO nanocomposite were prepared by autogenous pressure at elevated temperature (RAPET) method. The Pd/(NiO/MgO‐CNT) catalyst was characterized using X‐ray difraction (XRD), scanning electron microscopy (SEM), higher resolution‐transmission electron microscopy (HR‐TEM), Raman spectroscopy and electrochemical analysis. Electrochemical measurements demonstrate the as synthesized Pd/(NiO/MgO‐CNT) catalysts exhibit superior electrochemical performance compare to the commercial Pd/C catalysts. The current densities of the main anodic peak of electrooxidation of ethanol increases sharply for the Pd/(NiO/MgO‐CNT) (98.20 mA/cm2), which are ∼2.1 times as large as that of Pd/C (47 mA/cm2). The excellent electrochemical performance can be attributed on the one hand to the incorporation of NiO/MgO on palladium on the other hand to the porous tubular morphology of the CNT leads to high dispersion of Pd nanoparticles and also enhances the mass transport of the electrode.
Preparation of TiO2 Nanosponge‐Supported Noble Metal Catalysts and Their Application to 4‐Nitrophenol Reduction and CO Oxidation
Authors: Yang Man , Liu Xianchun , Li Yunfeng , Yu Xiaodan , Shi Zhan , Xing Yan 
Published: December 2017

AbstractIn this work, TiO2 nanosponge, replication of a bio‐template by a sol–gel method was achieved with filter paper. High‐dispersed Au and Pt nanoparticles (NPs) with controllable size were immobilized on the surface of TiO2 nanosponge, respectively. The obtained noble metal NPs/TiO2 nanosponge composites were characterized by various techniques. Catalytic activity of the synthesized Au/TiO2 nanocomposites was assessed by the reduction of 4‐nitrophenol (4‐NP), while the catalytic performance of the as‐synthesized Pt/TiO2 nanosponge composites was evaluated by the CO oxidation reaction. Notably, the Au/TiO2 and Pt/TiO2 nanocomposites demonstrated a good catalytic activity and stability for the catalytic reduction of 4‐NP and the catalytic oxidation of CO, respectively.
Facile Preparation of Biodegradable and Printable Polyester Films
Authors: Jain Nishant , Singh Ravinder , Kumar Gulshan , Pani Balaram , Nain Ratyakshi , Dutt Krishna , Muwal Pradeep Kumar , Sirohi Sidhharth 
Published: December 2017

AbstractIn this article, we present fabrication of ecofriendly, biodegradable and printable polyester films using polyethylene glycol, lactic acid and maleic anhydride as monomers. The susceptibility of polyester films towards biodegradation was tuned by varying lactic acid concentration. Films with 0.5 moles concentration of lactic acid exhibited maximum susceptibility towards degradation i. e. 39% in 60 days. Experimental results revealed that the films were printable with ink, label and stamp printing. The films were durable for tape and solvent test and capable of retaining dye on their surface owing to polar interactions between dye molecules and carboxylic groups of polymer chain ends.
Metal–Organic Framework‐Derived Materials for Sodium Energy Storage
Authors: Zou Guoqiang , Hou Hongshuai , Ge Peng , Huang Zhaodong , Zhao Ganggang , Yin Dulin , Ji Xiaobo 
Published: December 2017

AbstractRecently, sodium‐ion batteries (SIBs) are extensively explored and are regarded as one of the most promising alternatives to lithium‐ion batteries for electrochemical energy conversion and storage, owing to the abundant raw material resources, low cost, and similar electrochemical behavior of elemental sodium compared to lithium. Metal–organic frameworks (MOFs) have attracted enormous attention due to their high surface areas, tunable structures, and diverse applications in drug delivery, gas storage, and catalysis. Recently, there has been an escalating interest in exploiting MOF‐derived materials as anodes for sodium energy storage due to their fast mass transport resulting from their highly porous structures and relatively simple preparation methods originating from in situ thermal treatment processes. In this Review, the recent progress of the sodium‐ion storage performances of MOF‐derived materials, including MOF‐derived porous carbons, metal oxides, metal oxide/carbon nanocomposites, and other materials (e.g., metal phosphides, metal sulfides, and metal selenides), as SIB anodes is systematically and completely presented and discussed. Moreover, the current challenges and perspectives of MOF‐derived materials in electrochemical energy storage are discussed.
A Theoretical Review on Interfacial Thermal Transport at the Nanoscale
Authors: Zhang Ping , Yuan Peng , Jiang Xiong , Zhai Siping , Zeng Jianhua , Xian Yaoqi , Qin Hongbo , Yang Daoguo 
Published: December 2017

AbstractWith the development of energy science and electronic technology, interfacial thermal transport has become a key issue for nanoelectronics, nanocomposites, energy transmission, and conservation, etc. The application of thermal interfacial materials and other physical methods can reliably improve the contact between joined surfaces and enhance interfacial thermal transport at the macroscale. With the growing importance of thermal management in micro/nanoscale devices, controlling and tuning the interfacial thermal resistance (ITR) at the nanoscale is an urgent task. This Review examines nanoscale interfacial thermal transport mainly from a theoretical perspective. Traditional theoretical models, multiscale models, and atomistic methodologies for predicting ITR are introduced. Based on the analysis and summary of the factors that influence ITR, new methods to control and reduce ITR at the nanoscale are described in detail. Furthermore, the challenges facing interfacial thermal management and the further progress required in this field are discussed.
1D Nanomaterials: Design, Synthesis, and Applications in Sodium–Ion Batteries
Authors: Jin Ting , Han Qingqing , Wang Yijing , Jiao Lifang 
Published: December 2017

AbstractSodium–ion batteries (SIBs) have received extensive attention as ideal candidates for large‐scale energy storage systems (ESSs) owing to the rich resources and low cost of sodium (Na). However, the larger size of Na+ and the less negative redox potential of Na+/Na result in low energy densities, short cycling life, and the sluggish kinetics of SIBs. Therefore, it is necessary to develop appropriate Na storage electrode materials with the capability to host larger Na+ and fast ion diffusion kinetics. 1D materials such as nanofibers, nanotubes, nanorods, and nanowires, are generally considered to be high‐capacity and stable electrode materials, due to their uniform structure, orientated electronic and ionic transport, and strong tolerance to stress change. Here, the synthesis of 1D nanomaterials and their applications in SIBs are reviewed. In addition, the prospects of 1D nanomaterials on energy conversion and storage as well as the development and application orientation of SIBs are presented.