bluuebunny/crossref_metadata_2025_split huggingface dataset:
18F-florbetapir Positron Emission Tomography–determined Cerebral β-Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery
Authors: Klinger Rebecca Y. , James Olga G. , Borges-Neto Salvador , Bisanar Tiffany , Li Yi-Ju , Qi Wenjing , Berger Miles , Terrando Niccolò , Newman Mark F. , Doraiswamy P. Murali , Mathew Joseph P. 
Published: February 2018

Abstract

Background
Amyloid deposition is a potential contributor to postoperative cognitive dysfunction. The authors hypothesized that 6-week global cortical amyloid burden, determined by 18F-florbetapir positron emission tomography, would be greater in those patients manifesting cognitive dysfunction at 6 weeks postoperatively.

Methods
Amyloid deposition was evaluated in cardiac surgical patients at 6 weeks (n = 40) and 1 yr (n = 12); neurocognitive function was assessed at baseline (n = 40), 6 weeks (n = 37), 1 yr (n = 13), and 3 yr (n = 9). The association of 6-week amyloid deposition with cognitive dysfunction was assessed by multivariable regression, accounting for age, years of education, and baseline cognition. Differences between the surgical cohort with cognitive deficit and the Alzheimer’s Disease Neuroimaging Initiative cohorts (normal and early/late mild cognitive impairment) was assessed, adjusting for age, education, and apolipoprotein E4 genotype.

Results
The authors found that 6-week abnormal global cortical amyloid deposition was not associated with cognitive dysfunction (13 of 37, 35%) at 6 weeks postoperatively (median standard uptake value ratio [interquartile range]: cognitive dysfunction 0.92 [0.89 to 1.07] vs. 0.98 [0.93 to 1.05]; P = 0.455). In post hoc analyses, global cortical amyloid was also not associated with cognitive dysfunction at 1 or 3 yr postoperatively. Amyloid deposition at 6 weeks in the surgical cohort was not different from that in normal Alzheimer’s Disease Neuroimaging Initiative subjects, but increased over 1 yr in many areas at a rate greater than in controls.

Conclusions
In this study, postoperative cognitive dysfunction was not associated with 6-week cortical amyloid deposition. The relationship between cognitive dysfunction and regional amyloid burden and the rate of postoperative amyloid deposition merit further investigation.
Effect of a Short-term Cycle Ergometer Sprint Training Against Heavy and Light Resistances on Intraocular Pressure Responses
Authors: Vera Jesús , Garcia-Ramos Amador , Redondo Beatriz , Cárdenas David , De Moraes Carlos Gustavo , Jiménez Raimundo 
Published: February 2018

Purpose:
The purpose of this study is to determinate the long-term effect of a cycle ergometer sprint training program against heavy and light resistances on baseline intraocular pressure (IOP), and on the acute IOP response to cycling sprints.

Methods:
A total 27 physically active males were randomly assigned to a heavy loads group (HLG, n=9), low loads group (LLG, n=9), and control group (CG, n=9). Participants performed 12 training sessions during 6 weeks (2 sessions per week), and each training session consisted in performing 8 cycling sprints against either heavy (HLG) or light (LLG) resistances. Before and after intervention, they performed an identical protocol, which consisted in performing maximal cycling sprints against 5 different resistances in random order. In these protocols, IOP was measured before and after each sprint by rebound tonometry.

Results:
A Bayesian analysis revealed that baseline IOP was reduced in the LLG after the intervention [Bayes factor (BF01)=0.043 and effect size (ES)=1.255; pretest=15.22±0.94 mm Hg and posttest=15.39±1.02 mm Hg], whereas the HLG did not manifest any baseline IOP change (BF01=2.363 and ES=−0.205; pretest=15.28±1.44 mm Hg and posttest=14.17±1.77 mm Hg). The acute IOP response to maximal sprints was modified for the HLG, showing a more stable IOP response with heavier loads (resistance, 4 and 5) after the intervention (BF01<0.01 in both cases, and ESs=1.847 and 1.920, respectively).

Conclusions:
A short-term cycle ergometer sprint training impacts long-term IOP depending on the level of resistance imposed, showing that training with low loads permits to reduce baseline IOP, whereas training with heavy loads attenuates the acute IOP changes after sprinting against heavy loads.
The medical home for children with autism spectrum disorder: an essential element whose time has come
Authors: Todorow Carlyn , Connell James , Turchi Renee M. 
Published: February 2018

Purpose of review
The purpose of this review is to describe the role of the medical home in children with autism spectrum disorder (ASD). A high-quality medical home is essential, given the increase in prevalence of ASD and the array of services, community partners, specialists, therapists, and healthcare team members needed to care for this population.

Recent findings
Providing care through the medical home model results in fewer unmet needs. Care coordination and integration are the aspects of the medical home currently most lacking. Navigating the healthcare landscape for children with ASD may be enhanced with patient navigators, integration of physical and behavioral health, and telehealth services.

Summary
Children with ASD have an increased number of medical and mental health needs. Obtaining care via a medical home has been shown to decrease unmet healthcare needs. However, they are less likely to receive care through the medical home model compared with other children with special healthcare needs. Barriers identified by families include a lack of early identification, limited knowledge on educational plans, and unknown community resources. Barriers identified by providers include lack of time, training, and resources. Providing care coordination and family-centered care in a medical home model are essential for children with ASD.
Honest and cheating strategies in a simple model of aggressive communication: the role of spatial correlations
Authors: Számadó Szabolcs , Szántó András 
Published: February 2018

AbstractThe evolution and maintenance of communication in terms of aggressive interactions is a long-debated issue. Several game theoretical models and individual based computer simulations investigated this problem in terms of a simple game of aggressive communication. So far all of these investigations focused on well mixed population of individuals. However, spatial correlations can emerge in nature where individuals or group of individuals defend resources. The extensive literature on cooperative games show that these spatial correlations can be vital in the maintenance and evolution of cooperative strategies, thus it is reasonable to expect that such correlations could play an important role in the evolution of honest communication as well. Here we investigate a traditional game of aggressive communication in a spatially explicit context. We investigate the role of spatial correlations by comparing results of evolvability in well mixed populations with results from spatially explicit populations. Spatial correlations seem to inhibit the evolution of communication in the spatially explicit version of this game. This result is unexpected, and it requires further investigation to understand.
Plasma Membrane Phylloquinone Biosynthesis in Nonphotosynthetic Parasitic Plants
Authors: Gu Xi , Chen Ing-Gin , Harding Scott A. , Nyamdari Batbayar , Ortega Maria A. , Clermont Kristen , Westwood James H. , Tsai Chung-Jui 
Published: February 2018

AbstractPhylloquinone is a lipophilic naphthoquinone found predominantly in chloroplasts and best known for its function in photosystem I electron transport and disulfide bridge formation of photosystem II subunits. Phylloquinone has also been detected in plasma membrane preparations of heterotrophic tissues with potential transmembrane redox function, but the molecular basis for this noncanonical pathway is unknown. Here we provide evidence of plasma membrane phylloquinone biosynthesis in a nonphotosynthetic holoparasite Phelipanche aegyptiaca. A nonphotosynthetic and nonplastidial role for phylloquinone is supported by transcription of phylloquinone biosynthetic genes during seed germination and haustorium development, by plasma membrane-localization of alternative terminal enzymes, and by detection of phylloquinone in germinated seeds. Comparative gene network analysis with photosynthetically competent parasites revealed a bias of Phelipanche phylloquinone genes toward coexpression with oxidoreductases involved in plasma membrane electron transport. Genes encoding the plasma membrane phylloquinone pathway are also present in several photoautotrophic taxa of Asterids, suggesting an ancient origin of multifunctionality. Our findings suggest that nonphotosynthetic holoparasites exploit alternative targeting of phylloquinone for transmembrane redox signaling associated with parasitism.
Seave: a comprehensive web platform for storing and interrogating human genomic variation
Authors: Gayevskiy Velimir , Roscioli Tony , Dinger Marcel E , Cowley Mark J 
Published: February 2018

AbstractCapability for genome sequencing and variant calling has increased dramatically, enabling large scale genomic interrogation of human disease. However, discovery is hindered by the current limitations in genomic interpretation, which remains a complicated and disjointed process. We introduce Seave, a web platform that enables variants to be easily filtered and annotated with in silico pathogenicity prediction scores and annotations from popular disease databases. Seave stores genomic variation of all types and sizes, and allows filtering for specific inheritance patterns, quality values, allele frequencies and gene lists. Seave is open source and deployable locally, or on a cloud computing provider, and works readily with gene panel, exome and whole genome data, scaling from single labs to multi-institution scale.
Technological aspects of silver particle sintering for electronic packaging
Authors: Felba Jan 
Published: February 2018

PurposeThis paper aims to find proper technological parameters of low-temperature joining technique by silver sintering to eventually use this technique for reliable electronic packaging.Design/methodology/approachBased on the literature and author’s own experience, the factors influencing the nanosized Ag particle sintering results were identified, and their significance was assessed.FindingsIt has been shown that some important technological parameters clearly influence the quality of the joints, and their choice is unambiguous, but the meaning of some parameters is dependent on other factors (interactions), and they should be selected experimentally.Originality/valueThe value of this research is that the importance of all technological factors was analyzed, which makes it easy to choose the technological procedures in the electronic packaging.
When regulatory changes become a driver for business model innovation
Authors: Berti Chiara , Casprini Elena 
Published: February 2018

PurposeThe purpose of this paper is to provide an analysis of how an airport’s business model (BM) has been innovated. In particular, it considers a BM innovation owing to an exogenous driver, i.e. a change in the legislative environment.Design/methodology/approachThe paper presents an in-depth case study. It analyses the case of an Italian regional airport that has been renewed by changes in the National Plan of Transport.FindingsThe paper extends previous research on BM and air transport industry in two ways. First, the authors contribute to Gillen’s (2011) framework, via introducing a new kind of ownership/governance structure, that of long-term concession, characterized by the concession of the comprehensive management to a private company for 30 years. Second, the authors look at how a BM has been implemented and used as a manipulating device over the two phases of the airport development, namely, incubation and generation.Originality/valueThe paper provides an in-depth case study on an airport BM innovation.
Coopetition and institutions: a strategy for Brazilian wineries facing internationalization
Authors: Monticelli Jefferson Marlon , Garrido Ivan Lapuente , de Vasconcellos Silvio Luis 
Published: February 2018

PurposeThe purpose of this study is to understand the role institutions play in driving the internationalization of firms in an emerging country through promotion of coopetition. Investigating the relationships between coopetition, institutions and internationalization, especially among firms in emerging countries, is an important approach that has received little attention.Design/methodology/approachThis study has used a single case study interviewing managers of Brazilian wineries and representatives of formal institutions in an emerging economy. A research framework taking an institutions-based view of strategy and applying it to study coopetition and internationalization is proposed.FindingsFormal institutions are the most important players in the promotion of coopetition between firms in the Brazilian wine industry. Coopetition enables firms to access new resources and capabilities, promoting and facilitating internationalization, while also increasing firms’ competitiveness in the domestic market. The study also found evidence of certain limiting factors within these relationships, caused by the heterogeneous nature of the firms involved and by the asymmetries in their perceptions of the gains achieved.Research limitations/implicationsAs a consequence of the methodology adopted, the results of this study are limited to the Brazilian wine industry. Future research should extend the approach to data collected in different countries and industries. Another promising avenue for research is to explore how decisions of a political nature influence the institutions that coordinate an industry, which would provide a new perspective on the internationalization of the firms involved.Practical implicationsThe results offer governments and institutions an opportunity to better understand, and therefore to better manage, their actions in relation to their role in the promotion of the competitiveness of firms and industries, both in international and domestic markets. For firms, the results offer insights into the possible gains and the limitations of coopetition strategies, contributing to their decision-making on involvement. The study also contributes to understanding the competitiveness of the industry investigated.Originality/valueThis study approaches coopetition from the institutional perspective. It also focuses on internationalization of firms from an emerging country, which is characterized by a lack of firm-specific resources. The proposed framework seems promising for future research investigating coopetition and institutions within an integrated analytical framework.
“In sickness and in health, in poverty and in wealth?”
Authors: Roman Pais Seles Bruno Michel , Lopes de Sousa Jabbour Ana Beatriz , Chiappetta Jabbour Charbel Jose , Jugend Daniel 
Published: February 2018

Purpose“Economic crises” and “corporate social responsibility (CSR) initiatives” are two issues that dominate the modern business agenda. Although related, these issues have been analysed separately, and so a significant gap is perpetuated between the two. What are the effects of economic crises on CSR initiatives? Can organisational social initiatives withstand economic crises? The purpose of this paper is to answer these questions.Design/methodology/approachAn integrative literature review was conducted, considering: the economic and geographical context in which the research was conducted; the focus of each piece of research; the adopted research methods; organisational theories of analytical support; the sectors analysed; and the effects of economic crises on CSR initiatives and environmental management.FindingsSome of the findings were as follows: most of the studies analysed reported that CSR helps companies to cope with economic crises by increasing the efficiency of investments and establishing better relations with stakeholders and markets; environmental practices are related to negative environmental performance in periods of economic crises; and CSR relates positively to financial performance in periods of economic crises.Originality/valueThis is one of the first integrative literature reviews to investigate what happens to the relationship between businesses and sustainable change management in periods of crises. This paper also offers a future research agenda for the issue, with 12 questions still unanswered by the latest research.
Change management in Indo-Japanese cross-cultural collaborative contexts
Authors: Ashta Ashok , Stokes Peter , Hughes Paul 
Published: February 2018

PurposeWithin the globalized commercial context, Japanese business activity in India has increased significantly. The purpose of this paper is to highlight common attitudinal traits that would facilitate orientation of Indian executives towards Japanese management methods through, for instance “reverse adaptation”, using an approach other than cultural dimensions that have emerged in recent decades and consider how these play out in change management contexts.Design/methodology/approachA literature review was undertaken which found significant parallels between traditional Indian philosophy and modern Japanese management methods,inter alialong-term orientation, equanimity andNemawashi(pre-arranged participative decision making) and shared spiritual dimensions. The paper employed a methodology of participant observation and semi-structured interview approaches contextualized through lived experience methodology (Van Manen, 2015). These events are described and analysed narratively using a blend of qualitative participant observation and reflexive critical incident review.FindingsThe findings, by examining the confluence of Indian and Japanese management, provide an innovative avenue of research and theory for change management.Research limitations/implicationsThe research employs an inductive methodology which employs vignettes to examine Indo-Japanese contexts. The limits to generalization are recognized within the study. The paper offers important implications on Indo-Japanese collaboration and change management.Practical implicationsThese findings have important practical implications for Indian and Japanese managers who will be able to engage better within the dynamics of the Japanese work environment in Japanese subsidiaries in India. These same insights could also potentially facilitate wider examples of working in Japanese environments, either in Japan or outside Japan. At a more general level, the findings are relevant to all foreign investors in India for enhanced employee engagement by providing insights into spiritual values of Indian managers and their impact on change management situations.Social implicationsThere is emerging research on how traditional Indian philosophy tenets can be found in modern (western) management. This paper provides reasons, based in the extant literature, to believe that modern Japanese methods can trace their origin in Buddhist Indian philosophical thought and offer important implications for managing change.Originality/valueThe paper offers in-depth original insights into Indo-Japanese collaborative contexts.
Organizational, technological and extrinsic factors in the implementation of cloud ERP in SMEs
Authors: Gupta Shivam , Misra Subhas C. , Kock Ned , Roubaud David 
Published: February 2018

PurposeUse of cloud-based enterprise resource planning (ERP) services equips an SME to forego the requirements of high financial budget, IT infrastructure, and trained IT personnel as it is required for on-premise ERP solution. The purpose of this paper is to analyze the organizational and technological factors as well as the factors that concern the performance of cloud service provider. These concerns are known as extrinsic factors and they are compliance, network, and information security. This study links the organizational and technological factors of SMEs and the extrinsic factors of cloud vendor for the successful implementation of cloud ERP.Design/methodology/approachResource dependence theory (RDT) was used to understand the relationship of SMEs and cloud service provider. Structural equation modeling was employed in analyzing the data of 208 SMEs that were collected through a survey.FindingsThe empirical analysis supports the RDT as the critical success factors of the SMEs have a positive relationship with the extrinsic factors (compliance, network, and information security) during the cloud ERP implementation.Research limitations/implicationsThe data collected in this study is from India and this acts as a limitation as the result might not hold true for other countries and regions. Also, the data collected are cross-sectional and only represent the perspective of the respondents at the time of filling the questionnaire.Originality/valueThis paper attempts to bring out a relationship between SMEs and cloud service provider for the successful implementation of cloud ERP.
Service operations: what’s next?
Authors: Field Joy M. , Victorino Liana , Buell Ryan W. , Dixon Michael J. , Meyer Goldstein Susan , Menor Larry J. , Pullman Madeleine E. , Roth Aleda V. , Secchi Enrico , Zhang Jie J. 
Published: February 2018

PurposeThe purpose of this paper is to present exciting and innovative research questions in service operations that are aligned with eight key themes and related topics determined by theJournal of Service Management(JOSM) Service Operations Expert Research Panel. By offering a good number of such research questions, this paper provides a broad range of ideas to spur conceptual and empirical research related to service operations and encourage the continued creation of deep knowledge within the field, as well as collaborative research across disciplines that develops and incorporates insights from service operations.Design/methodology/approachBased on a Delphi study, described in the companion article, “Service Operations: What Have We Learned?,” the panel identified eight key research themes in service operations where leading-edge research is being done or has yet to be done (Victorinoet al., 2018). In this paper, three or four topics within each theme are selected and multiple questions for each topic are proposed to guide research efforts. The topics and questions, while wide-ranging, are only representative of the many ongoing research opportunities related to service operations.FindingsThe field of service operations has many interesting research topics and questions that are largely unexplored. Furthermore, these research areas are not only increasingly integrative across multiple themes within operations but often transcend functional disciplines. This creates opportunities for ever more impactful research with a greater reach throughout the service system and suggests that service researchers, regardless of functional affiliation, can contribute to the ongoing conversation on the role of service operations in value creation.Originality/valueLeveraging the collective knowledge of theJOSMService Operations Expert Research Panel to expand on the research themes generated from the Delphi study, novel questions for future study are put forward. Recognizing that the number of potential research questions is virtually unlimited, summary questions by theme and topic are also provided. These questions represent a synopsis of the individual questions and can serve as a quick reference guide for researchers interested in pursuing new directions in conceptual and empirical research in service operations. This summary also serves as a framework to facilitate the formulation of additional research topics and questions.