bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symptom management in complex post-traumatic stress disorder (ICD-11), view and experience of patients and their relatives: a mixed methods approach (Research Proposal)
Authors: Stadtmann Manuel P. , Maercker Andreas , Binder Jochen , Schnepp Wilfried 
Published: September 2017

Abstract
Objective
Using the framework of IDC-11, complex post-traumatic stress disorder will be diagnosed using the core criteria of a post-traumatic stress disorder and the presence of at least one symptom from the following three domains: symptoms of emotional dysregulation, negative self-concept, and problems in interpersonal relationships. In the literature, these symptoms are discussed as a common reason for seeking treatment. The symptoms can influence and impair the quality of life. This article describes a mixed methods study with a sequential exploratory design. The aim is to describe specific patient characteristics, levels of symptom burden and perspectives of adult inpatients and to describe the experiences, views and needs of patients’ relatives. The study will also investigate facilitators of and barriers to symptom management. The research will be conducted in four phases. The first phase will assess patients’ symptom burdens. The second phase will use semi-structured interviews to explore attitudes to symptom management and perceptions of patients and their relatives. The third phase will statistically explore hypotheses generated after the qualitative interviews. The fourth phase will mix the quantitative and qualitative results and interpret critically.

Results
The present study will add new results to the growing literature on complex post-traumatic stress disorder. These results could serve as the basis for further research into the development of interventions to improve symptom management.
Trial registration Ethical approval has been obtained from the Swiss cantonal ethic commission (Nr. 201500096). This research was also registered to the World Health Organization Clinical Trials Search Portal through the German Clinical Trial Register, Trial DRKS00012268 (21/04/2017)
Best proximity point theorems for generalized α-β-proximal quasi-contractive mappings
Authors: Ayari Mohamed Iadh 
Published: September 2017

AbstractHerein, we search for some best proximity point results for a novel class of non-self-mappings $T:A \longrightarrow B$
T
:
A
⟶
B
called generalized proximal α-β-quasi-contractive. We illustrate our work by an example. Our results generalize and extend many recent results appearing in the literature. Several consequences are derived. As applications, we explore the existence of best proximity points for a metric space endowed with symmetric binary relation.
Viraph: exploring the potentials of visibility graphs and their analysis
Authors: Amini Behbahani Peiman , Gu Ning , Ostwald Michael 
Published: September 2017

Abstract
Background
Visibility Graph Analysis (VGA) is a space syntax method for quantifying some socio-spatial properties of the built environment by mapping the floor plan into a grid. Presently, VGA mainly relies on mean values of the measures while the individual room-to-room (“interspatial”) relations are not considered or achievable by the common VGA software – depthMapX.

Methods
A new software package, Viraph, is developed using a weighed Dijkstra algorithm to calculate depths. The floor plan is mapped into convex areas to increase the speed of calculation. The interspatial relations are calculated by averaging the point-to-point depths in-between.

Results
The effectiveness of Viraph is demonstrated through a case study, which compares the houses from the late Victorian era with Wright’s Prairie style with a detailed analysis of Francis Little House (designed in 1902). In summary, Viraph has showed a significantly higher calculation speed for VGA, and capability of capturing some socio-spatial relations of the styles by measuring the interspatial depth.

Conclusions
Viraph’s improved speed for measurement has made VGA analysis more accessible for general design researchers and practitioners. Further this paper shows that the added feature of measuring the interspatial depth opens a new perspective for enhancing traditional space syntax analysis.
RETRACTED ARTICLE: Tridax procumbens flavonoids: a prospective bioactive compound increased osteoblast differentiation and trabecular bone formation
Authors: Al Mamun Md. Abdullah , Hosen Mohammad Jakir , Khatun Amina , Alam M. Masihul , Al-Bari Md. Abdul Alim 
Published: September 2017

Abstract
Background
The Tridax procumbens extracts (TPE) are known for their ethno-medicinal properties to increase osteogenic functioning in mesenchymal stem cells. Recently, we found that the T. procumbens flavonoids (TPF) significantly suppressed the RANKL-induced osteoclasts differentiation and bone resorption. The TPF also promoted osteoblasts differentiation and bone formation demonstrated by increasing bone formation markers in cultured mouse primary osteoblasts. However, the effects of the TPF on in vivo bone formation remain unclear. In this study, we investigated the effects of the TPF on in vivo bone formation, injected the TPF (20 mg/kg) twice a day in the low calcium diet mice and killed them after 21 day. Radiographic and histomorphometric analyses were performed on the dissected bones to determine the anabolic effects of the TPF.

Results
Bone mineral density and bone mineral content of the TPF-treated mice were significantly increased compared to the control mice. Bone formation-related indices like osteoblast number, osteoblast surface, bone volume, mineralizing surface, mineral apposition rate and bone formation rate were significantly increased in the TPF-treated mice compared to the control mice.

Conclusion
Our findings point towards the stimulation of bone formation by TPF, suggested that the TPF could be a potential natural anabolic agent to treat patients with bone loss-associated diseases such as osteoporosis.
Patient-Clinician Communication: American Society of Clinical Oncology Consensus Guideline
Authors: Gilligan Timothy , Coyle Nessa , Frankel Richard M. , Berry Donna L. , Bohlke Kari , Epstein Ronald M. , Finlay Esme , Jackson Vicki A. , Lathan Christopher S. , Loprinzi Charles L. , Nguyen Lynne H. , Seigel Carole , Baile Walter F. 
Published: September 2017

Purpose To provide guidance to oncology clinicians on how to use effective communication to optimize the patient-clinician relationship, patient and clinician well-being, and family well-being. Methods ASCO convened a multidisciplinary panel of medical oncology, psychiatry, nursing, hospice and palliative medicine, communication skills, health disparities, and advocacy experts to produce recommendations. Guideline development involved a systematic review of the literature and a formal consensus process. The systematic review focused on guidelines, systematic reviews and meta-analyses, and randomized controlled trials published from 2006 through October 1, 2016. Results The systematic review included 47 publications. With the exception of clinician training in communication skills, evidence for many of the clinical questions was limited. Draft recommendations underwent two rounds of consensus voting before being finalized. Recommendations In addition to providing guidance regarding core communication skills and tasks that apply across the continuum of cancer care, recommendations address specific topics, such as discussion of goals of care and prognosis, treatment selection, end-of-life care, facilitating family involvement in care, and clinician training in communication skills. Recommendations are accompanied by suggested strategies for implementation. Additional information is available at www.asco.org/supportive-care-guidelines and www.asco.org/guidelineswiki .
Duodenal Sodium/Glucose Cotransporter 1 Expression Under Fasting Conditions Is Associated With Postload Hyperglycemia
Authors: Fiorentino Teresa Vanessa , Suraci Evelina , Arcidiacono Gaetano Paride , Cimellaro Antonio , Mignogna Chiara , Presta Ivan , Andreozzi Francesco , Hribal Marta Letizia , Perticone Francesco , Donato Giuseppe , Luzza Francesco , Sesti Giorgio 
Published: September 2017

Abstract

Context
Type 2 diabetes (T2DM) is associated with a higher intestinal expression of the glucose transporters sodium/glucose cotransporter 1 (SGLT-1) and glucose transporter 2 (GLUT-2). It is currently unsettled whether prediabetes conditions characterized by postprandial hyperglycemia, such as impaired glucose tolerance (IGT) and normal glucose tolerance (NGT) with 1-hour postload glucose ≥155 mg/dL (8.6 mmol/L) (NGT-1h-high) are associated with increased expression of these glucose carriers in the intestine.

Objective
We evaluated whether duodenal abundance of SGLT-1 and GLUT-2 is augmented in subjects with IGT and NGT-1h-high, in comparison with subjects with NGT and 1-hour postload glucose ˂155 mg/dL (NGT-1h-low).

Design
Cross-sectional.

Patients
A total of 54 individuals underwent an upper gastrointestinal endoscopy.

Main Outcome Measures
Duodenal SGLT-1 and GLUT-2 protein and messenger RNA levels were assessed by Western blot and reverse transcription polymerase chain reaction, respectively.

Results
Of the 54 subjects examined, 18 had NGT-1h-low, 12 had NGT-1h-high, 12 had IGT, and 12 had T2DM. Duodenal SGLT-1 protein and messenger RNA levels were significantly higher in individuals with NGT-1h-high, IGT, or T2DM in comparison with NGT-1h-low subjects. GLUT-2 abundance was higher in individuals with T2DM in comparison with NGT-1h-low subjects; no substantial increase in GLUT-2 expression was observed in NGT-1h-high or IGT individuals. Univariate correlations showed that duodenal SGLT-1 abundance was positively correlated with 1-hour postload plasma glucose levels (r = 0.44; P = 0.003) but not with fasting or 2-hour postload glucose levels.

Conclusions
Duodenal SGLT-1 expression is increased in individuals with 1-hour postload hyperglycemia or IGT, as well as in subjects with T2DM, and it positively correlates with early postload glucose excursion.
Maternal Thyroid Antibodies Associates With Cardiometabolic Risk Factors in Children at the Age of 16
Authors: Heikkinen Anna-Leena , Päkkilä Fanni , Hartikainen Anna-Liisa , Vääräsmäki Marja , Männistö Tuija , Suvanto Eila 
Published: September 2017

Abstract

Context and Objective
The objective of this study was to determine the effects of maternal thyroid dysfunction or antibodies during pregnancy on the cardiometabolic risk factors in children.

Design, Setting, and Participants
This prospective population-based cohort study, Northern Finland Birth Cohort 1986, included all pregnancies within a year in the area. Maternal serum samples were collected before the 20th week of gestation and analyzed for thyrotropin, free T4, thyroid-peroxidase antibodies (TPO-Abs), and thyroglobulin antibodies (Tg-Abs). Cardiometabolic risk factors in children at the age of 16 years were evaluated via blood sampling and clinical examination. Data were available for 3229 to 4176 mother–child pairs.

Main Outcome Measures
Waist circumference, blood pressure, lipids and lipoproteins, and insulin resistance were measured. Odds ratios (ORs) with 95% confidence intervals (CIs) of cardiometabolic risk factors in children with and without mothers with thyroid dysfunction or antibodies were calculated with logistic regression and adjusted for covariates.

Results
Children of TPO-Ab–positive mothers had higher odds of metabolic syndrome (OR, 2.57; 95%, CI 1.26 to 5.25) and waist circumference indicative of metabolic syndrome (OR, 1.69; 95% CI, 1.14 to 2.50). They were also more likely to be overweight or obese (OR, 1.56; 95% CI, 1.04 to 2.34). Maternal thyroid dysfunction or Tg-Ab positivity did not associate with cardiometabolic risk factors in children.

Conclusion
Metabolic syndrome, greater waist circumference, and higher body mass index were more prevalent in children of TPO-Ab–positive mothers, indicating an adverse cardiovascular health profile.
Changing Their Tune: How Consumers’ Adoption of Online Streaming Affects Music Consumption and Discovery
Authors: Datta Hannes , Knox George , Bronnenberg Bart J. 
Published: September 2017

Instead of purchasing individual content, streaming adopters rent access to libraries from which they can consume content at no additional cost. In this paper, we study how the adoption of music streaming affects listening behavior. Using a unique panel data set of individual consumers’ listening histories across many digital music platforms, adoption of streaming leads to very large increases in the quantity and diversity of consumption in the first months after adoption. Although the effects attenuate over time, even after half a year, adopters play substantially more, and more diverse, music. Relative to music ownership, where experimentation is expensive, adoption of streaming increases new music discovery. While repeat listening to new music decreases, users’ best discoveries have higher play rates. We discuss the implications for consumers and producers of music. Data and the online appendix are available at https://doi.org/10.1287/mksc.2017.1051 .
Optimal Rebate Strategies Under Dynamic Pricing
Authors: Hu Shanshan , Hu Xing , Ye Qing 
Published: September 2017

Instant discounts and mail-in rebates are two common pricing tools in retail, but they are not simple substitutes. On the one hand, consumers discount the face value of a mail-in rebate, making it less effective than an instant discount in inducing consumers’ purchase. On the other hand, a portion of consumers with mail-in rebates fail to redeem them, resulting in savings for the retailer. We study how retailers, under pressure to move inventory, should use these two pricing tools to maximize revenue by determining the optimal use of mail-in rebates together with dynamic pricing of limited inventory. In a base model that allows frequent adjustment of product price and rebate face value, the optimal policy takes the form of “discount only,” “rebate only,” or a combination of the two. For useful heuristics with infrequent policy adjustment, we analyze the deterministic approximation of the base model. Interestingly, the deterministic solution splits the selling season into two segments, and it suggests using different pricing-rebate policies in each segment. Finally, we study a scenario in which the retailer has only one opportunity to introduce a static rebate, and we find that for any inventory level there is a cutoff time before which rebates should not be used. Our numerical studies show that such an optimal one-time static rebate policy performs well compared with the optimal revenue in the benchmark model. The online appendix is available at https://doi.org/10.1287/opre.2017.1642 .
Experiential Learning, Competitive Selection, and Downside Risk: A New Perspective on Managerial Risk Taking
Authors: Jaspersen Johannes G. , Peter Richard 
Published: September 2017

It is part of managerial wisdom that managers need to take risks in order to succeed. This is in stark contrast to the prominent agent-based theories of experiential learning and competitive selection that are known to be biased against risky alternatives in the long run. How can the positive managerial view on risk taking prevail given these results? Qualitative surveys of managers suggest risks to be acceptable if their outcome distribution meets certain criteria. We argue in this paper that these criteria are widely congruent with low downside risk. Using a novel simulation design, we analyze the effects of experiential learning and competitive selection on downside risk preferences in an ecology of agents. In the long run, experiential learning implies weak downside risk seeking, whereas competitive selection leads to strong downside risk aversion. Furthermore, competitive selection leads to the prevalence of outcome distributions with low downside risk in an ecology, even if they have a significantly higher level of total risk than comparable distributions with more downside risk. We draw implications for empirical studies on managerial behavior.The online appendix is available at https://doi.org/10.1287/orsc.2017.1149 .
Investment Of Temporarily Free Resources Of Czech Seniors – Present And Perspectives
Authors: Novotný Josef , Polách Jiří 
Published: September 2017

ABSTRACT
The article deals with investment of Czech seniors into investment instruments. This article aims to find out how seniors invest in investment instruments in the Czech Republic and how much of their retirement they are willing to invest. The main problem that occurs in the investment environment in the Czech Republic is a reluctance to invest public investment. The result is the finding whether the seniors investors invest or not, including the introduction of new knowledge arising from research conducted at the chosen target group on the basis of the questionnaire survey. Investors in retirement are an important group of investors in terms of population, where their number is growing every year. The disadvantage of the elderly is often neglected investment company with regard to their age and income.
Electronic Banking, Its Use and Safety. Are There Differences in the Access of Bank Customers by Gender, Education and Age?
Authors: Belás Jaroslav , Korauš Michal , Gabčová Lenka 
Published: September 2017

Abstract
Electronic banking is an important area of banking activities, under which the commercial banks try to retain existing clients or attract new customers through a better quality of service and decrease in prices of these services. The aim of the article was to examine selected attributes of security and the use of electronic banking and quantify differences in approach of the bank customers by gender, education and age. Our research confirmed that the dominant part of banking customers use electronic access when managing their personal finances. We found out that there are some differences in the approach of the bank customers in terms of their education. The customers with higher education to a greater extent and more intensively use electronic banking. In the safety area, we did not find any significant differences between banking clients by gender, education and age. The only exception is the finding that clients up to 35 years are significantly more confident in the use of electronic banking through public networks.
Social Customer Relationship Management: A Case Study
Authors: Paliouras Konstantinos , Siakas Kerstin V. 
Published: September 2017

Abstract
Social Customer Relationships Management (CRM) is a current business trend providing new channels of two-way communication with customers through social media sites, such as Facebook, Twitter etc. Social CRM enables companies to interact in an easy and contemporary way directly with customers as well as to track customer interactions and their social influence. In this paper we examine the importance of CRM, e-CRM and Social CRM for businesses. We provide perspectives on objectives and types of CRM, the working cycle of CRM, the stages of a CRM Strategy and technology tools that are used in CRM. Social CRM is in particularly analyzed, since this new trend requires active engagement by customers and other stakeholders. The engagement process is essential to successful Social CRM and to successful social business practices. Finally, we describe experiences from three family businesses that introduced Social CRM as a result of a project carried out as an assignment in the ‘Social Media Networking’ module of the MSc course in ‘Web Intelligence’ at the Department of Informatics of Alexander Technological Educational Institute of Thessaloniki. The assignment of the groups was to create a Social CRM Strategy in collaboration with a company. This study is a follow-up of the outcome of the projects carried out in the autumn semester 2014 and 2015. The results show that all three companies consider that Social CRM is an excellent tool for obtaining real time valuable data about customers and a cheap way to reach them.
Asymmetries of Maximum Trunk, Hand, and Leg Strength in Comparison to Volleyball and Fitness Athletes
Authors: Mattes Klaus , Wollesen Bettina , Manzer Stefanie 
Published: September 2017

Abstract
Mattes, K, Wollesen, B, and Manzer, S. Asymmetries of maximum trunk, hand, and leg strength in comparison to volleyball and fitness athletes. J Strength Cond Res 32(1): 57–65, 2018—Playing volleyball and corresponding training loads lead to specific strains and might result in asymmetric muscle pattern. The study aimed to identify volleyball-specific maximum bilateral strength asymmetries in comparison to fitness athletes. The cross-sectional study design compared an age-matched male volleyball group (n = 23; 27.9 ± 5 years) with a fitness group (n = 30; 26.3 ± 3 years). The participants performed an isometric maximum handgrip strength test followed by 2 isokinetic concentric maximum strength tests to determine the performance capacity of the axial trunk rotators (left-right) and bilateral leg extensors. Differences between groups and left-right side (within group) were proven by variance analysis with repeated measurements. There was a left-right difference with higher maximum forces for the rotation in the right direction in the volleyball group (p = 0.0058) but the group interaction effect was not significant after alpha error accumulation. The results of the leg press indicated a stronger left leg in the fitness group (nonsignificant) in comparison to the volleyball group. Overall, the volleyball group displayed symmetry in maximum handgrip and leg strength and asymmetry in trunk rotation with higher strength in right rotation. This asymmetry for the right trunk rotation showed a small effect size. The resulting asymmetry might be an adaptation to the volleyball techniques, but it remains unclear if this is a cause for or of injury. As a practical implication, the asymmetries should be examined to develop individualized strength training programs for both groups.