bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare presentations of glioblastoma multiforme in the septum pellucidum: illustrative case
Authors: Subah Galadu , Zeller Sabrina L , Kishore Jain Aarti , Gozum Nimrod , Smith Garrett , Cooper Jared , Kleinman George M , Gandhi Chirag D , Hanft Simon J 
Published: October 2024

BACKGROUND
Glioblastoma multiforme (GBM), a high-grade primary brain tumor, presents a formidable challenge in neuro-oncology because of its aggressive nature, infiltrative growth, and limited response to treatment. The septum pellucidum represents an uncommon and unexpected location for GBM, adding complexity to the diagnosis and management of this rare intracranial malignancy.

OBSERVATIONS
A 69-year-old male with a previous history of prostate carcinoma presented to an outside hospital with a 2-week history of a “trance-like state” and cognitive decline. Initial head computed tomography showed prominent ventricles without distinct mass lesions. Upon admission, magnetic resonance imaging demonstrated a mass within the inferior septum pellucidum extending to the third and both lateral ventricles. Biopsy findings indicated a GBM, World Health Organization central nervous system tumor grade 4, with immunopositivity for glial fibrillary acidic protein and a Ki-67 labeling index of 60%–70%.

LESSONS
Identifying only 5 cases in more than 60 years of literature, this systematic review illustrates the diverse clinical presentations, diagnostic advancements, and management approaches for septum pellucidum GBM.
https://thejns.org/doi/10.3171/CASE23770
Traumatic durotomy and entrapment of neural elements in a lumbar burst and laminar fracture diagnosed on preoperative imaging: illustrative case
Authors: Jarin Ian J , Samocha Yigal , Houten John K , Kinon Merritt D 
Published: October 2024

BACKGROUND
Traumatic dural lacerations can be caused by thoracolumbar burst fractures and, infrequently, can be associated with the entrapment of neural elements within a laminar fracture. The diagnosis of both is difficult to make on preoperative imaging, as the conditions are typically appreciated during surgical exploration. The authors present a case of traumatic durotomy with entrapment of neural elements in a laminar fracture that they believed could be appreciated on preoperative magnetic resonance imaging (MRI).

OBSERVATIONS
A young male involved in a motor vehicle collision presented to the authors’ trauma center with a lumbar burst and laminar fracture. Preoperative MRI demonstrated epidural hemorrhage and entrapment of neural elements within the laminar fracture, which was confirmed intraoperatively. The patient underwent a successful decompression, release of nerve roots, fusion, and recovery.

LESSONS
Traumatic durotomy and entrapment of neural elements can occur after a traumatic spinal fracture, and a diagnosis made upon preoperative MRI can allow for effective preoperative planning. Clinicians should have a high index of suspicion for these pathologies when encountering certain fracture patterns and could therefore tailor the surgical approach to avoid further neurological injury during surgery.
https://thejns.org/doi/10.3171/CASE24455
Evaluación del efecto de la aplicación de bioles y hongos micorrízicos arbusculares en Helianthus annuus para la biorremediación de suelos contaminados con zinc
Authors: Jurkauskas Campuzano Valeria , Tamayo Londoño Andrea , Osorno Bedoya Laura 
Published: October 2024

El zinc es un micronutriente esencial para el crecimiento y desarrollo de las plantas. Sin embargo, en altas concentraciones llega a ser tóxico, afectando negativamente a la planta y al suelo. Una de las alternativas para disminuir la concentración de este elemento en los suelos es la biorremediación, en la cual se puede utilizar plantas hiperacumuladoras de metales y microorganismos como los hongos micorrízicos arbusculares (HMA). El objetivo de este trabajo fue evaluar el efecto de la biorremediación de suelos contaminados con Zinc por Helianthus annus con adición de bioles e inoculación con HMA. El experimento se llevó a cabo bajo condiciones de invernadero por 90 días en un suelo con una concentración de 500 mg de Zinc /Kg. Los tratamientos consistieron en la inoculación o no de HMA y la adición de bioles como fertilizantes orgánicos. Los resultados muestran que las plantas de girasol lograron crecer en el suelo con 500 mg/Kg; su desarrollo fue significativamente mayor cuando fueron inoculadas con el hongo con una biomasa aérea de 28.11 g radicular 33.4 g comparada con los controles no inoculados 20.7 g y 25.3 g respectivamente y, presentaron una colonización micorrizal del 30 %. Al final del experimento, la concentración de Zinc en el suelo disminuyó en un 99,2 % con las plantas no inoculadas y, al inocularlas con los HMA, en un 99,6 %. La planta de girasol es una alternativa ambientalmente sostenible y estética para biorremediar suelos contaminados con metales; los HMA mejoran la biorremediación y el desarrollo de las plantas en presencia de metales.
The Position of Czechoslovakia in the World Economy
Authors: Novozámský Jiří , Tauchman Josef 
Published: October 2024

If we determine the position of any country in the world economy, we must monitor this position in a twofold sense, in the formal sense and in the absolute sense. The formal status is given by the socio-economic form, i.e. the ruling type of production relations. The formal position of socialist countries in relation to each other is therefore equal, while the formal position of countries belonging to the world system of capitalism may be unequal, for example, when it comes to the relationship between an economically developed country and an economically less developed country. It is also about the unequal formal status of countries in the relationship between a socialist country and a capitalist country. The absolute structure of the country is determined by the economic level, or the ratio of the economic levels of different countries. The absolute position of a country in the world economy therefore depends on the amount of social labor expended in a certain social form (simple labor, private labor, capital, etc.) put into the creation of the social product of a given country, and this is calculated per inhabitant . In this sense, the position of countries in the world system of capitalism and socialism is mostly unequal.
PENERAPAN BUKU PRAKTEK UBUDIYAH SSKU (STANDAR SISWA KADER ULAMA) DALAM MENUNJANG PEMBELAJARAN PAI
Authors: Durrotun Nafisah  , Imam Athoir Rokhman  
Published: October 2024

The implementation of SSKU (Standard Student Cadre of Ulama) ubudiyah activities as a support for Islamic Religious Education (PAI) learning at MA Almaarif Singosari. This research aims to: (1) Identify the content of the material in the SSKU ubudiyah practice book, and (2) Analyze how the book is implemented at MA Almaarif Singosari.
This research used a descriptive qualitative approach, with data obtained through interviews, observation, and documentation. The data were then analyzed qualitatively to describe the application of SSKU.
The results showed that: (1) The content of the material in the SSKU ubudiyah practice book is considered good because it covers the cognitive, affective, and psychomotor aspects of students at each level of education (ula, wustho, and 'ulya). (2) The implementation of the SSKU book goes through three main stages: planning (determining objectives, procedures, and schedules), implementation (including memorization activities, explaining, and individual and group practice), and annual evaluation to assess the implementation and success of the SSKU book as needed.
Relación neutrófilo-linfocito, Valor Pan-Inmune-Inflamatorio y relación plaquetas-linfocito como marcadores pronósticos de sobrevida libre de recurrencia en cáncer cervicouterino localmente avanzado, en el Hospital Miguel Hidalgo de la ciudad de Aguascalientes
Authors: Alatriste Martínez Sara , Rosas Cabral Alejandro , Gómez Villalobos Lázaro , Rodríguez Vargasargas Daniel , Ramos Franco César Enrique , Vázquez Rodríguezguez Eduardo , Gutiérrez  Campos Rafael 
Published: October 2024

Resumen: Introducción: El cáncer cervicouterino (CaCU) sigue siendo una importante causa de mortalidad en nuestro país y en Aguascalientes. Objetivo: Evaluar el impacto pronóstico de la relación neutrófilo-linfocito (RNL), la relación plaquetas-linfocito (RPL) y el Valor Pan-Inmune-Inflamatorio (VPI) en la sobrevida libre de recurrencia (SLR) de pacientes con CaCU localmente avanzado. Material y métodos: Estudio observacional, retrospectivo, longitudinal en el que se incluyeron 65 pacientes con CaCU localmente avanzado tratadas con quimio-radioterapia concomitante. Se utilizaron curvas ROC, método de Kaplan-Meier para determinar la SLR, prueba de Log-Rank y se realizó análisis univariado y multivariado. Resultados: La mediana de la SLR en las pacientes con una RNL ≥2.4 fue de 55 meses contra 8 meses de las pacientes con una RNL <2.4 (p=0.0089). Para la RPL ≥147 fue de 65 meses contra 8 meses en las pacientes con RPL<147 (p=0.001). Para el VPI ≥310 la mediana de la SLR fue de 55 versus 6 meses en las pacientes con un VPI <310, (p=0.008). En el análisis univariado el riesgo relativo (RR) de la RNL ≥2.4 fue de 2.104 (IC95% 1.1-4.23, p= 0.025); para la RPL fue de 1.008 (IC95% 1.001-1.015, p=0.041) y para el VPI 1.006 (IC95% 1.001-1.01, p=0.016). En el análisis multivariado solamente la RNL (p= 0.025) y el VPI (p=0.03) mantuvieron significancia. Conclusión: Una RNL ≥2.4 y un VPI > 310 se asocian significativamente con un mayor riesgo de recurrencia en pacientes con cáncer cervicouterino localmente avanzado; aunque se requiere de estudios prospectivos que confirmen estos hallazgos.

Fecha de recepción: 22/07/2023
Aceptación de originales: 05/08/2024
A ECOLOGIA HUMANA DE ROBERT PARK E A EXPANSÃO DOS CONDOMÍNIOS HORIZONTAIS FECHADOS NA CIDADE DE MOSSORÓ/RN
Authors: Santos João Paulo Silva dos 
Published: October 2024

A partir do surgimento das ciências sociais as problemáticas relacionadas as formas de moradia nas grandes cidades do século XIX tornaram-se destaque. Os relatos da obra de Friedrich Engels, "The Condition of Working Classes in England", de 1884, fez surgir novos pensamentos sobre a questão. No iní­cio do século XX, foram idealizadas maneiras de resolver os problemas evidenciados por Engels. Planejadores urbanos como Ebenezer Howard, Patrick Geddes, Georges-Eugène Haussmann e Le Corbusier destacaram-se na busca por soluções para a implantação de espaços habitacionais menos insalubres. Em contraponto, a forma de organização das moradias urbanas e os modos de vida na cidade não foram somente relacionados com questões urbaní­sticas. Robert Ezra Park desenvolveu teorias sobre os processos de interação entre indiví­duos e comunidades na cidade. Com base nos conceitos de zonas morais e áreas naturais de Park e na atual realidade da expansão dos condomí­nios horizontais fechados na cidade de Mossoró, este estudo pretende identificar a possibilidade de utilização das concepções teóricas do autor para o entendimento do espraiamento desses empreendimentos na cidade. De caráter exploratório, este estudo possui como base de dados fontes bibliográficas. As concepções de Park, intrinsecamente, não possuem lastro suficiente para promoverem entendimentos sobre os fenômenos envolvidos nas determinações dos locais de moradias no ambiente urbano de Mossoró. O fenômeno do espraiamento dos condomí­nios horizontais fechados na cidade está mais relacionado as formas especulativas de negociação das terras urbanas do que com a escolha subjetivamente cultural.
Seroprevalence, risk factors, and therapeutic response of feline panleukopenia in household cats at Savar Upazila of Dhaka district in Bangladesh
Authors: Jubaer - , Rahman Md Mamunur , Ahmed Md Selim 
Published: October 2024

Feline panleukopenia is a single-stranded DNA virus. It is a highly contagious and often lethal viral infection in cats. The present study aimed to determine the seroprevalence, associated common risk factors, and therapeutic response of the disease in cats in the study area. The disease was diagnosed based on history, characteristic clinical findings, and laboratory diagnosis by a Rapid diagnosis test kit. Information on age, season, sex, and immune status was evaluated to determine the risk factors of feline panleukopenia virus infection in cats. The present investigation showed that 58.33% of cats tested positive for FPV. In addition, cats under the age of six months had a greater incidence of infection (67.12%) than cats between the ages of seven and twelve months (59.18%) and cats over twelve months (38.24%). Winter (68.18%) had a higher prevalence of FPV than summer (52.83%) and rainy (48.65). In the present study, male cats had a higher frequency of FPV (60.49%) than female cats (56%). The non-vaccinated cats exhibited FPV positive (62.96%) compared to vaccinated cats (28.57%). In addition, 42 (46.15%) animals had full recovery from infection. The recovery rate (65.52%) of cats aged 7 to 12 months was higher than that of two other age groups. Additionally, more cats were recovered in the summer season (64.29%) than in the winter (33.33%) or during the rainy season (50%). Compared to non-vaccinated cats (44.71%), FPV-positive vaccinated animals have demonstrated a higher recovery percentage (66.66%). Proper hygienic management and vaccination are important measures to check the FPV infection in cats. The status of the prevalence and associated risk factors is necessary to control the fatal infection of cats in the study area.
Asian J. Med. Biol. Res. 2024, 10(4), 141-147
Hubungan Kecerdasan Emosional Dengan Kenakalan Remaja di Sekolah Menengah Kejuruan Negeri 1 Padang
Authors: Aprilia Feby , Renidayati Renidayati , Herwati Herwati , Sasmita Heppi , Tasman Tasman 
Published: October 2024

Angka kenakalan remaja mengalami peningkatan 0,70% dapat dilihat dari tingginya kenakalan remaja seperti membolos, merokok, berkelahi, dll. Kenakalan remaja dipengaruhi beberapa factor yaitu keluarga, teman sebaya yang kurang baik, lingkungan tempat tinggal serta kecerdasan emosional yang rendah. Kecerdasan emosional mampu mengendalikan remaja dengan baik untuk membangun diri sendiri ,memahami diri sendiri dan hubungan interpersonal yang baik dengan orang lain. Penelitian ini bertujuan untuk mengetahui hubungan kecerdasan emosional dengan kenakalan remaja. Penelitian ini dilakukan bulan Oktober 2022-Juni 2023 di Sekolah Menengah Kejuruan Negeri 1 Padang. Desain penelitian Cross Sectional. Populasi pada yaitu 481 orang dan sampel 83 orang menggunakan rumus Slovin. Teknik pengumpulan data menggunakan kuesioner dan google form. Analisis data dengan uji Chi-Square. Hasil penelitian menunjukkan remaja mengalami kecerdasan emosional rendah (53,0%) dan remja mengalami kenakalan remaja tinggi (54,2%) ada hubungan antara kecerdasan emosional dengan kenakalan remaja di Sekolah Menengah Kejuruan Negeri 1 Padang dengan nilai (p-Value 0,012). Berdasarkan hasil penelitian diharapkan melalui Kepala Sekolah Menengah Kejuruan Negeri 1 padang pada guru Bimbingan konseling (BK) memberikan edukasi tentang cara mengatasi kenakalan remaja dengan meningkatkan kecerdasan emosional dengan cara mendorong siswa berfikir positif dan melatih cara berhubungan baik dengan orang lain.
A novel framework for elucidating the effect of mechanical loading on the geometry of ovariectomized mouse tibiae using principal component analysis
Authors: Moraiti Stamatina , Cheong Vee San , Dall’Ara Enrico , Kadirkamanathan Visakan , Bhattacharya Pinaki 
Published: October 2024

IntroductionMurine models are used to test the effect of anti-osteoporosis treatments as they replicate some of the bone phenotypes observed in osteoporotic (OP) patients. The effect of disease and treatment is typically described as changes in bone geometry and microstructure over time. Conventional assessment of geometric changes relies on morphometric scalar parameters. However, being correlated with each other, these parameters do not describe separate fractions of variations and offer only a moderate insight into temporal changes.MethodsThe current study proposes a novel image-based framework that employs deformable image registration on in vivo longitudinal images of bones and Principal Component Analysis (PCA) for improved quantification of geometric effects of OP treatments. This PCA-based model and a novel post-processing of score changes provide orthogonal modes of shape variations temporally induced by a course of treatment (specifically in vivo mechanical loading).Results and DiscussionErrors associated with the proposed framework are rigorously quantified and it is shown that the accuracy of deformable image registration in capturing the bone shapes (∼1 voxel = 10.4 μm) is of the same order of magnitude as the relevant state-of-the-art evaluation studies. Applying the framework to longitudinal image data from the midshaft section of ovariectomized mouse tibia, two mutually orthogonal mode shapes are reliably identified to be an effect of treatment. The mode shapes captured changes of the tibia geometry due to the treatment at the anterior crest (maximum of 0.103 mm) and across the tibia midshaft section and the posterior (0.030 mm) and medial (0.024 mm) aspects. These changes agree with those reported previously but are now described in a compact fashion, as a vector field of displacements on the bone surface. The proposed framework enables a more detailed investigation of the effect of disease and treatment on bones in preclinical studies and boosts the precision of such assessments.
Prediction of in-hospital mortality risk for patients with acute ST-elevation myocardial infarction after primary PCI based on predictors selected by GRACE score and two feature selection methods
Authors: Tang Nan , Liu Shuang , Li Kangming , Zhou Qiang , Dai Yanan , Sun Huamei , Zhang Qingdui , Hao Ji , Qi Chunmei 
Published: October 2024

IntroductionAccurate in-hospital mortality prediction following percutaneous coronary intervention (PCI) is crucial for clinical decision-making. Machine Learning (ML) and Data Mining methods have shown promise in improving medical prognosis accuracy.MethodsWe analyzed a dataset of 4,677 patients from the Regional Vascular Center of Primorsky Regional Clinical Hospital No. 1 in Vladivostok, collected between 2015 and 2021. We utilized Extreme Gradient Boosting, Histogram Gradient Boosting, Light Gradient Boosting, and Stochastic Gradient Boosting for mortality risk prediction after primary PCI in patients with acute ST-elevation myocardial infarction. Model selection was performed using Monte Carlo Cross-validation. Feature selection was enhanced through Recursive Feature Elimination (RFE) and Shapley Additive Explanations (SHAP). We further developed hybrid models using Augmented Grey Wolf Optimizer (AGWO), Bald Eagle Search Optimization (BES), Golden Jackal Optimizer (GJO), and Puma Optimizer (PO), integrating features selected by these methods with the traditional GRACE score.ResultsThe hybrid models demonstrated superior prediction accuracy. In scenario (1), utilizing GRACE scale features, the Light Gradient Boosting Machine (LGBM) and Extreme Gradient Boosting (XGB) models optimized with BES achieved Recall values of 0.944 and 0.954, respectively. In scenarios (2) and (3), employing SHAP and RFE-selected features, the LGB models attained Recall values of 0.963 and 0.977, while the XGB models achieved 0.978 and 0.99.DiscussionThe study indicates that ML models, particularly the XGB optimized with BES, can outperform the conventional GRACE score in predicting in-hospital mortality. The hybrid models' enhanced accuracy presents a significant step forward in risk assessment for patients post-PCI, offering a potential alternative to existing clinical tools. These findings underscore the potential of ML in optimizing patient care and outcomes in cardiovascular medicine.
Hepatopulmonary syndrome secondary to metabolic associated fatty liver disease in childhood — novel treatment with growth hormone replacement therapy: a case report and systematic review of literature
Authors: Choe Yunsoo , Lee Yun Jeong , Lee Young Ah , Ko Jae Sung , Shin Choong Ho 
Published: October 2024

ObjectiveHepatopulmonary syndrome (HPS) is a rare complication of metabolic associated fatty liver disease (MAFLD) occurring subsequent to hypopituitarism, often developing after resection of hypothalamic or pituitary tumors. The aim of this study is to report an illustrative case of an HPS patient who was successfully treated with growth hormone replacement therapy, without liver transplantation which is conventionally regarded as the only treatment option. Additionally, we conducted a comprehensive review of published case reports of HPS in the pediatric population.MethodsWe systematically searched literature databases to identify case reports and case series of HPS associated with hypopituitarism diagnosed in childhood. The search included MEDLINE/PubMed, Scopus, Embase, and Google Scholar from 1990 to 2023. The review process adhered to the PRISMA checklist for comprehensive reporting and methodological transparency.ResultsAn 18-year-old female, who had been followed up for MAFLD after craniopharyngioma resection, presented with cyanosis and progressive dyspnea. She was diagnosed with severe degree of HPS. The patient began treatment with recombinant human growth hormone, leading to a significant improvement in respiratory symptoms within 3 months, and normalization of lung shunt ratio after 6 months of therapy. In our systematic review, nine patients from nine studies across six countries were identified. The median age at diagnosis of hypopituitarism was 10.5 years (range 1–16 years), and HPS was diagnosed at a median interval of 7 years later (range 0–26 years). Half of the patients had not received growth hormone therapy after being diagnosed with hypopituitarism, which subsequently led to the diagnosis of HPS. Three patients underwent liver transplantation, but non-alcoholic steatohepatitis recurred in all cases. Six patients were successfully treated with growth hormone replacement therapy without undergoing liver transplantation.ConclusionsHPS can occur in pediatric patients with MAFLD who have undergone resection of the tumor in the hypothalamus or pituitary gland. Our findings suggest that growth hormone replacement therapy can be a possible alternative to liver transplantation for HPS patients. However, further investigations need to be performed to validate the efficacy of growth hormone treatment in different causes of HPS cases.