bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing upconversion luminescence intensity of BiTa7O19:Er3+/Yb3+/Mo4+ by doping Sc3+ or Sb
Authors: Li Lei , Cao Yongze , Li Guojian , Yan Xianglan , Wang Xuekai , Zhang Xizhen , Chen Baojiu 
Published: September 2024

AbstractBased on the previous optimal concentration of Er3+/Yb3+/Mo4+ co‐doped BiTa7O19 (BTO) samples, Sc3+ or Sb is planned to be doped into BTO:Er3+/Yb3+/Mo4+ for further improving the upconversion luminescence (UCL) intensity under 980‐nm laser excitation. A series of BTO:Er3+/Yb3+/Mo4+/Sc3+ and BTO:Er3+/Yb3+/Mo4+/Sb samples are prepared by high‐temperature solid‐phase sintering method. The microstructure and UCL properties are investigated by X‐ray diffraction, Raman, X‐ray photoelectron spectroscopy (XPS), diffuse reflection, and luminescence spectrum. The green UCL intensity of BTO:Er3+/Yb3+/Mo4+/Sb is little better than that of BTO:Er3+/Yb3+/Mo4+/Sc3+, which reaches 2.40 times than that of β‐NaYF4:Er3+/Yb3+. XPS results show that Sc is 3+, Mo is 4+, and Sb is 3+ and 5+. Raman spectra show that BTO:Er3+/Yb3+/Mo4+/Sb has lower phonon energy and more disorder than BTO:Er3+/Yb3+/Mo4+/Sc3+. The maximum relative temperature sensitivity is got as 0.01012 K−1 at 303 K based on luminescence intensity ratio technology. BTO:Er3+/Yb3+/Mo4+/Sb has outstanding pure green UCL intensity, which can be applied to luminescence display and temperature sensing.
The positive F wave in lead V1 of typical atrial flutter is caused by activation of the right atrial appendage: Insight from mapping during entrainment from the right atrial appendage
Authors: Yamashita Shu , Mizukami Akira , Ono Maki , Hiroki Jiro , Miyakuni Shota , Arashiro Takumi , Ueshima Daisuke , Matsumura Akihiko , Miyazaki Shinsuke , Sasano Tetsuo 
Published: September 2024

AbstractIntroductionTypical atrial flutter (AFL) is a macroreentrant tachycardia in which intracardiac conduction rotates counterclockwise around the tricuspid annulus. Typical AFL has specific electrocardiographic characteristics, including a negative sawtooth‐like wave in the inferior lead and a positive F wave in lead V1. This study aimed to analyze the origin of the positive F wave in lead V1, which has not been completely understood.MethodsThis study enrolled 10 patients who underwent radiofrequency catheter ablation for a typical AFL. Electroanatomical mapping was performed both during typical AFL and entrainment from the right atrial appendage (RAA). The 12‐lead electrocardiogram (ECG) and three‐dimensional (3D) electroanatomical maps were analyzed.ResultsThe positive F wave in lead V1 changed during entrainment from the RAA in all the cases. The 3D map during entrainment from the RAA revealed an area of antidromic capture around the RAA, which collided with the orthodromic wave in the anterior right atrium. This area of antidromic capture around the RAA was the only difference from the 3D electroanatomical map of AFL and is considered the cause of the change in the F wave in lead V1 during entrainment.ConclusionThe analysis of the differences in the 12‐lead ECG and 3D maps between tachycardia and entrainment from the RAA clearly demonstrated that activation around the RAA is responsible for the generation of the positive F wave in lead V1 of typical AFL.
Decoding functional impact of epigenetic regulator mutations on ligand–receptor interaction perturbations for evaluation of cancer immunotherapy
Authors: Shi Aiai , Lin Chaohuan , Lyu Jie 
Published: September 2024

AbstractCellular crosstalk mediated by ligand–receptor interactions largely complicates the tumour ecosystem, resulting in heterogeneous tumour microenvironments that affect immune response and clinical benefits from immunotherapy. Epigenetic mechanisms are pivotal to expression changes of immune‐related genes and can modulate the anti‐tumour immune response. However, the functional consequences of disrupted epigenetic regulators (ERs) on ligand–receptor interactions in the tumour microenvironment remain largely unexplored. Here, we proposed mutations of ERs in perturbed interactions (MERIN), a molecular network‐based approach that incorporates multi‐omics data, to infer the potential consequences of ER mutations on ligand–receptor interaction perturbations. Leveraging cancer genomic profiles and molecular interaction data, we comprehensively decoded the functional consequences of ER mutations on dysregulated ligand–receptor interactions across 33 cancers. The dysregulated ligand–receptor genes were indeed enriched in cancer and immune‐related function. We demonstrated the potential significance of PD1–PDL1 interaction‐related ER mutations in stratifying cancer patients from multiple independent data cohorts. The ER mutation group showed distinct immunological characterizations and prognoses. Furthermore, we highlighted that the ER mutations could potentially predict clinical outcomes of immunotherapy. Our computational and clinical assessment underscore the utility of MERIN for elucidating the functional relevance of ER mutations in cancer immune response, potentially aiding patients' stratification for immunotherapy.
Systematic review/meta‐analysis on the role of CB1R regulation in sleep‐wake cycle in rats
Authors: Xue Jianjun , Xu Ziqing , Zhang Jie , Hou Huaijing , Ge Long , Yang Kehu 
Published: September 2024

AbstractObjectiveA systematic review/meta‐analysis was conducted to investigate the effect of cannabinoid type‐1 receptor (CB1R) regulation on the sleep‐wake cycle of rats and to provide new ideas and evidence‐based basis for clinical research on the treatment of sleep disorders.MethodsWe searched Cochrane Library, PubMed, Web of Science, Embase, Chinese Biomedicine Literature Database (CBM), China National Knowledge Infrastructure, WanFang, and VIP databases for relevant papers, about the effects of CB1R agonists/antagonists on sleep‐wake cycle in rats, from inception to November 2023. Two reviewers performed study screening, data extraction, and risk of bias assessment using the SYRCLE's risk of bias tool. Meta‐analysis was performed using RevMan 5.3 software. Heterogeneity test was performed on the included studies (Test standard α = 0.1). I2 value was used to evaluate the heterogeneity. Forest plot was drawn, and p ≤ 0.05 indicates statistically significant difference.ResultsA total of 16 trials involving 484 experimental rats were included. The methodological quality evaluation results showed that the overall quality of the included studies was low. The results of the meta‐analysis showed that single administration of CB1R agonists could shorten the wakefulness (W) time in the first 6 h (h) (standardized mean difference (SMD) = –2.52, 95% confidence interval (CI) (–3.83, –1.22), p = 0.0002) and 24 h (SMD = –0.84, 95% CI (–1.31, –0.36), p = 0.0005) after administration, prolong nonrapid eye movement sleep (NREM) time (SMD = 1.75, 95% CI (0.54, 2.95), p = 0.005) and rapid eye movement sleep (REM) time (SMD = 1.76, 95% CI (0.26, 3.26), p = 0.02), and increase REM frequency after administration (SMD = 1.67, 95% CI (0.98, 2.35), p < 0.00001), these results were all statistically different. There were no significant differences in sleep latency and average duration of REM. Single administration of CB1R antagonists prolonged the first 6 h W time after administration (SMD = 1.36, 95%CI (0.29, 2.43), p = 0.01), shortened the first 6 h NREM time (SMD = –1.73, 95% CI (–2.88, –0.57), p = 0.003) and REM time (SMD = –2.07, 95% CI (–3.17, –0.96), p = 0.0003) after administration, and increased the frequency of W after administration (SMD = 3.57, 95% CI (1.42, 5.72), p = 0.001). There was no statistical difference in the average duration of W. REM time and REM frequency increased after continuous CB1R agonist withdrawal.ConclusionsAccording to the existing evidence, CB1R played a pivotal role in regulating the sleep‐wake cycle in rats. CB1R agonists tended to reduce W time, increase NREM and REM sleep times, boost REM frequency, and promote sleep. Conversely, CB1R antagonists could increase the duration and frequency of W, shorten NREM and REM sleep times, and promote W.
Managerial myopia and corporate financialization: Evidence from China
Authors: Zhang Cheng , Liu Cheng , Ma Yaoying , Yang Chunhong 
Published: September 2024

AbstractWhile managerial characteristics significantly impact corporate strategies, the role of managerial myopia in corporate financialization remains underexplored. Using data from a sample of 20,881 firm‐year observations of Chinese firms from 2007 to 2019, we examine how managerial myopia influences corporate financialization. We find that managerial myopia promotes corporate financialization. The results are robust to various measures of financialization, alternative specifications, and considerations of endogeneity. Further analysis reveals that external supervision, indicated by analyst attention and institutional investor shareholdings, mitigates the positive effect of managerial myopia on corporate financialization. By contrast, corporate pressures, such as default risk and competitive pressure, amplify the tendency toward financialization.
Differential performance of aqueous‐ and ethylic‐Lugol's iodine stain to visualize anatomy in μCT‐scanned vertebrates
Authors: Crowell Hayley L. , Nagesan Ramon S. , Davis Rabosky Alison R. , Kolmann Matthew A. 
Published: September 2024

AbstractMuseum specimens are an increasingly important tool for studying global biodiversity. With the advent of diffusible iodine‐based contrast‐enhanced computed tomography (diceCT), researchers can now visualize an organism's internal soft tissue anatomy without the need for physical dissection or other highly destructive sampling methods. However, there are many considerations when deciding which method of staining to use for diceCT to produce the best gray‐scale contrast for facilitating downstream anatomical analyses. The general lack of direct comparisons among staining methodologies can make it difficult for researchers to determine which approaches are most appropriate for their study. Here, we compare the performance of ethylic‐Lugol's iodine solution with aqueous‐Lugol's staining solution across several vertebrate orders to assess differential imaging outcomes. We found that ethylic‐Lugol's is better for visualizing muscle attachment to bone but provides overall lower contrast between soft tissue types. Comparatively, aqueous‐based Lugol's provides high‐contrast imaging among soft tissue types, although bone is more difficult to discern. We conclude that the choice of staining methodology largely depends on the type of anatomical data the researcher wishes to collect, and we provide a decision‐based framework for assessing which staining methodology (ethylic or aqueous) is most appropriate for desired imaging results.
Pharmacies Counselling of Patients in the Era of Antifungal Resistance
Authors: Alcoat Catja , Christensen Elisabeth M. M. , Jemec Gregor B. E. , Skov Kenneth , Saunte Ditte M. L. 
Published: September 2024

ABSTRACTBackgroundTinea pedis is one of the most prevalent superficial fungal infections. Initial antifungal treatment is often acquired over‐the‐counter (OTC) without previous consultation with a physician.ObjectiveLately, increasing antifungal terbinafine resistance has been documented in Denmark and globally and it is therefore of interest to assess how Danish pharmacies advise customers with tinea pedis.MethodsOne hundred Danish pharmacies were randomly selected and an employee interviewed from each. A structured question guide was followed, with the possibility to add further comments.ResultsInterviews of 94 pharmacies were conducted. Six pharmacies never replied. Terbinafine as standard dose or cutaneous solution terbinafine one time application (Lamisil Once (R)) were recommended by 99% of the pharmacy employees as first‐line treatment. The customer was advised to seek medical attention when tinea pedis was recurring (93%), or when treatment duration was > 2 weeks (77%). The majority (88%) of the pharmacy employees had no knowledge about antifungal resistance.ConclusionOnly few pharmacy employees were aware of the current problem of antifungal resistance and the majority advised costumers to initiate treatment using OTC topical terbinafine. The problem of emerging antifungal resistance requires attention in order to provide customers with tinea pedis effective treatment and prevent further societal spread of resistance to antifungals.
Sit venia verbo: A case for dermacriticism
Authors: Hron Irina 
Published: September 2024

AbstractThis article introduces the term “skinnedness” as a complementary notion to what we commonly refer to as skin. The term allows for a fundamental conceptual discussion that brings together human skin, animal skin, and other types of organic or artificial skin, such as fruit skin or the soft outer layer of a doll. The dermacritical approach developed here explores the unique affordances of skin and skin‐like phenomena, including their “graphordance,” that is, the implicit invitation to write on them. Through a thorough discussion of works by Oskar Kokoschka, Hermine Moos, Lester Gaba, and Herta Müller, this paper offers a philosophically and historically informed perspective on the skinnedness of skin, integrating its symptomatic, semantic, and aesthetic dimensions from a comparative literary perspective.
The Immune Priming in Aquaculture Invertebrates: Inspiration From Cellular Perspective and Future Investigation
Authors: Wang Weilin , Wang Lingling , Song Linsheng 
Published: September 2024

ABSTRACTAquatic invertebrates account for more than 33.4% of global aquaculture production and are important aquaculture animals worldwide. Although the frequent outbreaks of diseases and the lack of disease prevention strategies have greatly hindered further development of the invertebrate aquaculture industry. Immune priming is a phenomenon that invertebrates mount a faster and stronger secondary response than that of the primary response when encountered with a given microbe. It has been demonstrated to be present in a wide range of aquaculture species and would provide a fresh idea for disease prevention. As the main executors of immune defense in invertebrates, the circulating hemocytes are short‐lived, and the solution for the paradox of keeping a long‐lasting immune protection might lie in the formation of long‐lived memory cells in immune priming. As a reference for the access of memory cell formation processes in aquaculture invertebrates, the cellular kinetics including expansion, contraction, and memory formation of lymphocytes in the adaptive immunity of vertebrates are discussed. Then the features of hemocytes in aquaculture invertebrates, and their kinetic changes of cell number and immune capacity during immune priming are summarized for the knowledge of a stronger secondary immune response. The regulatory roles of epigenetic modification and metabolic reprogramming in immune priming and their possible functions in memory cell formation and identification are proposed to be preferentially investigated for further clarifying the mechanism of immune priming, which might provide a novel entrance for understanding the mechanisms of immune priming and developing disease prevention strategy in aquaculture invertebrates.
Drafting an image of success: the Russian patronage of émigré Elisabeth Louise Vigée Lebrun
Authors: Wilson Erin 
Published: September 2024

AbstractPainted as a stipulation of her honorary admission into Russia's Imperial Academy of Arts, Elisabeth Louise Vigée Lebrun's (1755–1842) Self‐Portrait of 1800 is notable for having been produced at the culmination of a decade spent in exile. It depicts a strong, triumphant woman at the height of her career. Despite substantial research into other areas of her life, Vigée Lebrun's time spent as an émigré has been little studied. Fleeing France at the onset of the Revolution in 1789, she travelled extensively throughout Europe. Although her early years abroad, from 1789 to 1795, are marked by a sense of constant relocation, her later years in Russia are notable for her prodigious output and her stable existence in Saint Petersburg. This article seeks to highlight the importance of Vigée Lebrun's time at the court of Catherine the Great and her son Paul I in relation to her broader émigré experience. It illuminates how exile in Russia, far from condemning Vigée Lebrun to obscurity, fostered her career in ways that other countries had not.
Money, methods, and morals: What are development economists up to?
Authors: Hoeffler Anke , Khera Reetika 
Published: September 2024

AbstractIn the highly competitive field of publishing in economics journals, methods often become fads sometimes to the detriment of framing meaningful research agendas and of research ethics. In recent times, empirical work based on primary data collection has gained traction. Randomized controlled trials entail not just primary data collection but also interventions involving human subjects. Field research involving data collection is also expensive, raising a number of concerns. In this special symposium we explore questions of research agendas and research ethics, and argue fo rthe acceptance of broader methodological approaches, greater inclusion in the publication process and for a reflection at the disciplinary level of practices related to field research.
Alveolar bone healing patterns in chronic kidney failure and kidney transplant recipients: A pixel intensity and fractal analyses
Authors: Lins Paula J. B. , Andrade Natalia S. , Caliento Rubens , Sarmento Dmitry J. S. , Zambrana Jéssica R. M. , Costa Claudio , Gallotini Marina 
Published: September 2024

AbstractAimsTo assess and compare radiographically the alveolar bone after tooth extractions in individuals with chronic kidney failure undergoing hemodialysis (CKFh), those submitted to kidney transplantation (KT), and those without kidney disease (CG) by using fractal analysis (FA) and pixel intensity (PI).Methods and resultsPeriapical radiographs of 48 CKFh individuals (87 extracted teeth), 12 KT individuals (26 extracted teeth and 29 control individuals [76 extracted teeth] were analyzed at 7 and 60 days after tooth extraction. Fractal dimension (FD) and PI were assessed to evaluate the alveolar trabecular bone structural complexity and mineral content. The difference in FD values between the 7th and 60th postoperative days in KT individuals (0.03 ± 0.08) was significantly lower compared to those of CKFh individuals (0.09 ± 0.10) and controls (0.15 ± 0.06). As for the difference in PI values, KT (4.55 ± 10.24) and CKFh groups (9.88 ± 15.90) showed significantly lower values compared to those of the control group (17.93 ± 11.86) in the same period. These results indicate a lower gain in the trabecular bone complexity and bone density in the alveolus of KT individuals compared to the other groups.ConclusionsOverall mineral content and thickness of the bone in the plane of the x‐ray beam were lower in KT and CKFh individuals compared to controls, reflecting the need for careful consideration in recommending rehabilitation with dental implants for these patients. Particular attention should be given to the potential challenges in oral rehabilitation of KT patients.
Soil carbon sequestration cannot be enhanced efficiently under all‐straw return in cool semiarid regions: Evidences from a long‐term experiment in a crop rotation system
Authors: Yin Jiade , Ren Xuling , Hou Huizhi , Ma Mingsheng , Fang Yanjie , Liu Yanlan , Lei Kangning 
Published: September 2024

AbstractCrop straw return is one of the most important measures to increase soil organic carbon (SOC) content in farmland systems. However, the effects of crop straw return amount on SOC sequestration (SCS) in long‐term crop rotation system is unclear, especially in typically cool and dry regions. A field experiment was conducted from 2015 to 2020 in a wheat‐maize‐potato rotation system including four straw treatments: without straw incorporation (CK), 1/3 straw incorporation (LS), 2/3 straw incorporation (MS), and all‐straw incorporation (HS), respectively. After 6 years of cropping, SCS in 0–30‐cm soil layer of CK, LS, MS, and HS increased by 3.6, 7.0, 7.8, and 9.9 Mg ha−1, compared with the beginning of the experiment, respectively. In particular, SCS in 20–30‐cm soil layer of CK was obviously increased by 2.7 Mg ha−1. When compared with CK, straw incorporation increased total dry matter, total evapotranspiration, SCS, and water productivity by 29.3%, 3.4%, 28.8%, and 25.2% on average, respectively, but decreased pure carbon accumulation and water use efficiency of carbon sequestration. Although the carbon input and SCS showed a linear positive correlation with evapotranspiration, the carbon input efficiency was negatively correlated with pure carbon accumulation in HS and MS. When compared with LS, the carbon input efficiency decreased by 64.1% in HS, restricting SCS. These results indicated that 1/3 straw incorporation could increase SCS efficiency as well as decrease carbon loss in the–crop system, making it more suitable for application in cool semiarid region, and revealed that excessively straw returning to the field could not improve SCS efficiency.
Influence of corn stalk and corn stalk biochar application on the strategy of phosphorus sorption and release in brown earth
Authors: Cao Dianyun , Cao Yufeng , Tong Shishi , Liu Sainan , Chen Wenfu , Meng Jun , Lan Yu 
Published: September 2024

AbstractThe characteristics of soil phosphorus (P) fixation and release have a critical impact on the availability of P and the risk of environmental loss. Investigation of the effects of corn stalk and corn stalk biochar on the P adsorption–desorption characteristics of brown earth can provide a theoretical basis for the rational return of crop stalk to the field and improving the availability of soil P. The Langmuir adsorption isotherm equation provided a better fit than the Freundlich equation for the curve of soil P adsorption and equilibrium solution P concentration. Biochar application increased the maximum adsorption capacity (MAC) and maximum buffer capacity (MBC) of the soil for P by 8.5% and 17.2%, respectively. Corn stalk and its biochar reduced the P adsorption saturation (DPS) by 41.8% and 31.9%, respectively, but increased the amount of readily desorbable P (RDP) by 39.7% and 154.4%, respectively. The application of corn stalk and its biochar improved the soil P desorption rate at substrate P concentrations of less than 5 mg L−1, whereas significant reductions in the soil P desorption rate were observed between 5 mg L−1 and 30 mg L−1, and no significant effects were observed at P concentrations over 40 mg L−1. In addition, the total P and Olsen‐P contents of the soil were significantly associated with the P adsorption–desorption process (p < .05). Therefore, corn stalk and corn stalk biochar can enhance the capacity of soil for P adsorption, with a stronger effect observed for biochar than for corn stalk, and the rate of P desorption from treated soil is dependent on P concentration in the soil solution.
On tame ramification and centers of F$F$‐purity
Authors: Carvajal‐Rojas Javier , Fayolle Anne 
Published: September 2024

AbstractWe introduce a notion of tame ramification for general finite covers. When specialized to the separable case, it extends to higher dimensions the classical notion of tame ramification for Dedekind domains and curves and sits nicely in between other notions of tame ramification in arithmetic geometry. However, when applied to the Frobenius map, it naturally yields the notion of center of ‐purity (aka compatibly ‐split subvariety). As an application, we describe the behavior of centers of ‐purity under finite covers — it all comes down to a transitivity property for tame ramification in towers.