bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of Visceral Fat Area with Metabolic Risk Factors in Romanian Patients: A Cross-Sectional Study
Authors: Hâncu Anca , Radulian Gabriela 
Published: January 2016

Abstract
Background and Aims: The aim of the present study was to investigate the relationship between visceral fat area (VFA), estimated by bioimpedance, and cardiovascular risk factors independent of BMI and waist circumference in a cohort of Romanian patients. Material and Methods: This was a cross-sectional study, in which were collected data from 751 patients ≥18 years of age from Cluj-Napoca. Anthropometric, biochemistry, body composition and medical history parameters were recorded from patients’ files. Results: Compared with the participants with VFA <100 cm2, those with VFA ≥100 cm2 had significantly worse levels of the laboratory parameters describing the glycemic metabolism, lipid metabolism and liver functions (p <0.05 for all). A higher percentage of participants with VFA ≥100 cm2 had diabetes, obesity, hypertension, hypertriglyceridemia and hypo-HDL cholesterolemia (p <0.05 for all). VFA was correlated with systolic and diastolic blood pressure, total and LDL-cholesterol levels, triglycerides, ALT, previous diagnosis of diabetes, hypertriglyceridemia and hypo-HDL cholesterolemia independent of BMI and waist circumference. Conclusions: Among this cohort of Romanian adults, an increasing level of visceral adiposity was correlated with worse lipid and glucose metabolism parameters as well as with increased levels of ALT, which probably reflects liver fat deposition.
Usefulness of Reticulocyte Hemoglobin Equivalent in Management of Regular Hemodialysis Patients with Iron Deficiency Anemia
Authors: Dalimunthe Naomi Niari , Lubis Abdurrahim Rasyid 
Published: January 2016

Introduction. Reticulocyte hemoglobin equivalent (RET-He) is a new parameter for evaluating iron status. This study aims to assess diagnostic value and investigate RET-He as early predictor of response to intravenous iron supplementation.
Methods. Seventy-two regular hemodialysis patients at Adam Malik Hospital were studied from April to May 2011. RET-He was compared with conventional iron parameters for identification of iron deficiency. Fifteen patients with iron deficiency anemia were selected to receive 100 mg iron sucrose intravenous during every dialysis session (2x/weeks) for 4 weeks.
Results. Receiver operating characteristic (ROC) curve for RET-He revealed the value of area under the curve was 0.818 (p < 0.0001). Using cutoff level 31.65 pg, RET-He showed 81.5% sensitivity and 61.6% specificity. Serum ferritin (r = 0.499, p < 0.0001) and transferrin saturation/ TSAT (r = 0.592, p<0.0001) were correlated to RET-He. Significant improvement in hemoglobin, hematocrit and RET-He were found after intervention (p = 0.023, p = 0.049 and p = 0.019, respectively).
Conclusion. RET-He is a useful marker of iron deficiency and early predictor of response to intravenous iron supplementation in regular hemodialysis patients.
Immunohistochemical Aspects of Cell Death in Diabetic Nephropathy
Authors: Bălăşescu Elena , Cioplea Mirela , Brînzea Alice , Nedelcu Roxana , Zurac Sabina , Ion Daniela Adriana 
Published: January 2016

Introduction. Diabetes Mellitus causes ultrastructural changes triggered by partially clarified cellular mechanisms. Since cell death is an important mechanism in the appearance and progression of diabetic nephropathy, we studied alteration of several markers of apoptotic pathways signaling in renal tissue of diabetic or prediabetic patients.
Methods. We analyzed 48 human kidney tissue samples divided into two study groups: the research group (43 renal tissue samples from diabetic or prediabetic patients), and the control group (5 renal tissue samples from patients without diabetes). Immunohistochemistry revealed expression of Bcl-2, APAF-1, CD-95 and Caspase-9 in the renal cortical structures. Statistical analysis was also performed (significance level P<0.05).
Results. We found a variable expression of the antiapoptotic Bcl-2 with a decrease of Bcl-2 expression in diabetes. The control samples render evident intensely positive immunostaining for CD-95. In diabetes and diabetic nephropathy, there was positive immunostaining for APAF-1 at tubular cell level. Nuclear and cytoplasmic positivity for Caspase-9 was more frequently recorded as kidney damage progresses. APAF-1 and Caspase-9 positivity are arguments for an intrinsic apoptotic mechanism of cell death in diabetic nephropathy.
Conclusion. The mechanisms of apoptotic cell death identified in diabetic kidney samples prove that Bcl-2, CD-95, APAF-1 and Caspase-9 represent reliable markers of cell death in human renal tissue. Our results support the hypothesis that apoptosis is a pathogenic and initiator mechanism of renal remodeling in diabetic kidney disease.
ST Segment Elevation Myocardial Infarction Due to Severe Ostial Left Main Stem Stenosis in a Patient with Syphilitic Aortitis
Authors: Predescu L.M. , Zarma L. , Platon P. , Postu M. , Bucsa A. , Croitoru M. , Prodan B. , Chioncel O. , Delean D. 
Published: January 2016

Cardiovascular manifestations of tertiary syphilis infections are uncommon, but represent an important cause of mortality and morbidity. Syphilitic aortitis is characterized by aortic regurgitation, dilatation of ascending aorta and ostial coronary artery lesions.
We report a case of 36 years old man admitted to our hospital for acute anterior ST segment elevation myocardial infarction complicated with cardiogenic shock (hypotension 75/50 mmHg). Transthoracic echocardiography revealed a dilated left ventricle with severe systolic dysfunction (ejection fraction = 25%), severe mitral regurgitation, moderate aortic regurgitation and mildly dilated ascending aorta. Coronary angiography showed a severe ostial lesion of left main coronary artery which was treated by urgent stent implantation and an intra-aortic contrapulsation balloon was implanted. Blood tests for syphilitic infection were positive. The patient was discharged with treatment including benzathine penicillin.
In our case, we present an acute manifestation of a syphilitic ostial left main stenosis treated by primary percutaneous coronary intervention in acute myocardial infarction. Long term follow-up of the patient is crucial as a result of potential rapid in-stent restenosis caused by continuous infection of the ascending aorta.
This case is particular because it shows that syphilitic aortitis can be diagnosed in acute settings, like ST segment elevation myocardial infarction.
Step training in a rat model for complex aneurysmal vascular microsurgery
Authors: Martin Dan , Gorgan Mircea Radu 
Published: January 2016

Abstract
Introduction: Microsurgery training is a key step for the young neurosurgeons. Both in vascular and peripheral nerve pathology, microsurgical techniques are useful tools for the proper treatment. Many training models have been described, including ex vivo (chicken wings) and in vivo (rat, rabbit) ones. Complex microsurgery training include termino-terminal vessel anastomosis and nerve repair. The aim of this study was to describe a reproducible complex microsurgery training model in rats. Materials and methods: The experimental animals were Brown Norway male rats between 10-16 weeks (average 13) and weighing between 250-400g (average 320g). We performed n=10 rat hind limb replantations. The surgical steps and preoperative management are carefully described. We evaluated the vascular patency by clinical assessment-color, temperature, capillary refill. The rats were daily inspected for any signs of infections. The nerve regeneration was assessed by foot print method. Results: There were no case of vascular compromise or autophagia. All rats had long term survival (>90 days). The nerve regeneration was clinically completed at 6 months postoperative. The mean operative time was 183 minutes, and ischemia time was 25 minutes.
Peculiarities of us Border Guard Officers’ Training at the Federal Law Enforcement Training Center Using Online Campus
Authors: Bloshchynskyi Ihor 
Published: January 2016

Abstract Professional training of future US border guard officers at the Federal Law Enforcement Training Center using e-FLETC Online Campus has been substantiated in the article. Special attention has been paid to revealing such topical areas of Online Campus computer-based training modules (crime scene, driver training, drugs, firearms, health, interviewing, investigative, legal, mapping, maritime, officer safety, technology, terrorism, traffic stops, training) that include over 120 lessons and 20 videos which are available on a wide range of topics. Web-based training lessons which include topics such as counterterrorism, crime scene preservation and documentation, disaster, crisis and emergency strategies and management, domestic violence, drug endangered children, drug related crimes, elder abuse, firearms, fitness and healthy lifestyles, human trafficking, interacting with special needs populations, intelligence led policing, interpersonal skills and conflict management, interviews and interrogations, investigating technology related crimes (protecting and collecting digital evidence), investigative skills and techniques, knowledge of laws and regulations, leadership and management, lessons learned (previous case analysis), maritime law enforcement, etc. have been revealed. Besides, examples of “Firearms” and “Use of Force” curricula in e-FLETC Online Campus have been presented.
The System of Teacher Education Management in Great Britain
Authors: Chychuk Antonina 
Published: January 2016

Abstract The system of teacher education management, namely, forms and principles of teacher education management according to the normative base (Education Reform Act (1988); Education Act (1992; 1993; 1996; 1997; 2002); School Standards and Framework Act (1998); Higher Education Act (2004), etc.), monitoring and participation of the public in its management have been analyzed. It has been proved that lately the democratization process in British education management has been combined with the increased attention of the state to monitoring, requirements to appropriate activity of educational establishments and trends seem to be forward education quality enhancing, democratization of evaluation, monitoring and information providing processes. Changes in education management in the historical context have been considered. The organizations participating in education management in Great Britain have been outlined. The data has been presented that enabled to distinguish similarities and differences in the functioning of the organizations participating in education management in Great Britain and ensure the existing of independent management authorities within them.
Content of Bachelors’ in Tourism Informative Training in Ukrainian and Polish Experience: Comparative Study
Authors: Zubekhina Tetiana 
Published: January 2016

Abstract This article provides a comparative analysis of the content of Bachelors’ in Tourism informative training in Ukrainian and Polish experience. The content of Bachelors’ in Tourism informative training in Ukraine and Poland has been analyzed. The content of subjects, namely, “Information Technologies in Tourism” and “The Foundations of Bachelors’ in Tourism Information Culture” being the basis of Bachelors’ in Tourism informative training in Ukraine has been justified. It has been concluded that the study of foreign experience in specialists’ professional training, in particular, specialists’ in tourism, that requires critical analysis of achievements in education systems abroad and outlining of positive aspects of such experience, is extremely necessary for the development of higher education in Ukraine as the implementation of new information technologies into educational process creates optimal conditions for the forming of students’ information culture that is not limited to knowledge and skills in the field of information processing and implies the development of the personality, his/her preparation for professional careers in the information society.
Delayed Justice - Macedonian Experience With Guilty Plea And Sentence Bargaining
Authors: Misoski Boban 
Published: January 2016

Abstract
Bearing on mind the idea of the proverb “Justice Delayed is Justice Denied” Macedonian Legislator within the new Code of Criminal Procedure (CPC) has introduced several legal mechanisms for accelerating the criminal procedure. The most important instruments among them, by all means, are the Guilty Plea and Sentence Bargaining.
In this article, the author elaborates the practical implementation of these CPC’s provisions and performs analysis of its implementation by the Basic Court Skopje 1 in Skopje, as the biggest and most caseload-burdened court in Macedonia, and by the Public Prosecution Office in Skopje.
The analysis discovered several weak points, which should be properly addressed, both through theoretical scrutiny and through introduction of amendments to the CPC or through production of a general opinion by the Supreme Court. Only through these amendments to the legal provisions of the CPC can be expected to have improved court practice in a manner which would accentuate the real/just benefits of these instruments for accelerating of the criminal procedure.
Several conclusions and suggestions for improvement or specific issues, which were determined as problematic were developed, such as: tackling the impact of a guilty plea by one of the codefendants to the other codefendants who did not plead guilty; treatment of the altered statement by one of the codefendants during the plea agreement and its use against the other codefendant; and the burden of proof and amount of evidence which is necessary to support the sentence bargaining process.
The Right To Appeal For The Social Insurance As A Human And Constitutional Right
Authors: Selita Mirela 
Published: January 2016

Abstract
Magna Carat is a highly significant document that found the way into the rights and the constitutions. Magna Carat is a symbol of human and constitutional rights. Social insurance is part of the social security and the recognition of social security as a basic human right is enshrined in the Universal Declaration of Human Rights adopted by the United Nations General Assembly on 10 December 1948 at the Palais de Chaillot, Paris and furthermore the European Conventions on Human Rights, specially the article 6.
Magna Carat demonstrated the limitations from the arbitrarily. Magna Carat is a foundation of the powers of Parliament and the legal principles, as the rule of law, the rule that everybody has equality before the law. It promised the access to justice. In that respect Magna Carta is still a challenge for many states and officials. The myth of Magna Carta is the protection of the personal rights and is held in great respect by the legal communities against the arbitrary of the authority
In respect of the aim of this international conference to see the way how these principles have found their implementation in contemporary legislations as well as to identify the problems that occur regarding these rights, an overview of the Albanian right to appeal for the social insurance rights. The right to appeal to higher authorities against any decisions and the judicial review against the unfavorably resolved appeals.
Affect and Nostalgia in Eva Hoffman’s Lost in Translation
Authors: Kella Elizabeth 
Published: January 2016

Abstract
This article examines the affective terrain of Poland, Canada, and the US in Eva Hoffman’s autobiographical account of her migration and exile in Lost in Translation: A Life in a New Language (1989), the text that launched Hoffman’s reputation as a writer and intellectual. Hoffman’s Jewish family left Poland for Vancouver in 1959, when restrictions on emigration were lifted. Hoffman was 13 when she emigrated to Canada, where she lived until she went to college in the US and began her career. Lost in Translation represents her trajectory in terms of “Paradise,” “Exile,” and “The New World,” and the narrative explicitly thematizes nostalgia. While Hoffman’s nostalgia for post-war Poland has sometimes earned censure from critics who draw attention to Polish anti-Semitism and the failings of Communism, this article stresses how Hoffman’s nostalgia for her Polish childhood is saturated with self-consciousness and an awareness of the politics of remembering and forgetting. Thus, Hoffman’s work helps nuance the literary and critical discourse on nostalgia. Drawing on theories of nostalgia and affect developed by Svetlana Boym and Sara Ahmed, and on Adriana Margareta Dancus’s notion of “affective displacement,” this article examines Hoffman’s complex understanding of nostalgia. It argues that nostalgia in Lost in Translation is conceived as an emotion which offers the means to critique cultural practices and resist cultural assimilation. Moreover, the lyricism of Hoffman’s autobiography becomes a mode for performing the ambivalence of nostalgia and diasporic feeling.
Literariness and Racial Consciousness in Paule Marshall’s Memoir Triangular Road and Gloria Naylor’s Fictionalized Memoir 1996
Authors: Łobodziec Agnieszka 
Published: January 2016

Abstract
Black American women writers were side-lined by the literary canon as recently as the 1980s. Today, as a result of their agency, a distinct literary tradition that bears witness to black women’s particular expressiveness is recognized. Bernard Bell observes that the defining features common to most literary works by black American women are a focus on racist oppression, black female protagonists, the pursuit of demarginalization, women’s bonding, women’s relationship with the community, the power of emotions, and black female language. Although these elements refer predominantly to novels, they are also present in Paule Marshall’s memoir Triangular Road (2009) and Gloria Naylor’s fictionalized memoir 1996 (2005). Moreover, the two works are fitting examples of racial art, the point of departure of which, according to Black Arts Movement advocates, should be the black experience. Actually, since through memoirs the authors offer significant insights into themselves, the genre seems closer to this objective of racial art than novels. At the same time, taking into consideration the intricate plot structures, vivid images, and emotional intensity, their memoirs evidence the quality of literariness i.e., in formalist terms, the set of features that distinguish texts from non-literary ones, for instance, reports, articles, text books, and encyclopaedic biographical entries. Moreover, Marshall and Naylor utilize creative imagination incorporating fabulation, stories within stories, and people or events they have never personally encountered, which dramatizes and intensifies the experiences they relate. In Marshall’s memoir, the fictitious elements are discernable when she imagines the historical past. Naylor demarks imagined narrative passages with separate sections that intertwine with those based upon her actual life experience.
Biodegradation Of 4-Chlorobiphenyl By Pseudomonas synxantha
Authors: Dhanjal Noorpreet Inder Kaur , Cameotra Swaranjit Singh 
Published: January 2016

Abstract
The stabilization and disposal of polychlorinated biphenyls (PCBs) from soil environment and wetland areas is of great concern for health and safety. Wetland remediation with microorganisms is an approach for treating PCBs. A bacterial strain was isolated from hydrocarbon contaminated soil of Ropar, Punjab, able to degrade PCBs under aerobic conditions. The percentage of degradation with 100 mM/ml of 4-chlorobiphenyl was up to 90%. Degradation was monitored by mass spectrometry, high performance liquid chromatography and spectrophotometrically, showing that 4-chlorobiphenyl was degraded almost completely. The bacterial strain was identified as Pseudomonas synxantha by 16sRNA sequencing method. This is the first report of 4-chlorobiphenyl degradation by Pseudomonas synxantha.
Antisense transcription as a tool to tune gene expression
Authors: Brophy Jennifer AN , Voigt Christopher A 
Published: January 2016

AbstractA surprise that has emerged from transcriptomics is the prevalence of genomic antisense transcription, which occurs counter to gene orientation. While frequent, the roles of antisense transcription in regulation are poorly understood. We built a synthetic system in Escherichia coli to study how antisense transcription can change the expression of a gene and tune the response characteristics of a regulatory circuit. We developed a new genetic part that consists of a unidirectional terminator followed by a constitutive antisense promoter and demonstrate that this part represses gene expression proportionally to the antisense promoter strength. Chip‐based oligo synthesis was applied to build a large library of 5,668 terminator–promoter combinations that was used to control the expression of three repressors (PhlF, SrpR, and TarA) in a simple genetic circuit (NOT gate). Using the library, we demonstrate that antisense promoters can be used to tune the threshold of a regulatory circuit without impacting other properties of its response function. Finally, we determined the relative contributions of antisense RNA and transcriptional interference to repressing gene expression and introduce a biophysical model to capture the impact of RNA polymerase collisions on gene repression. This work quantifies the role of antisense transcription in regulatory networks and introduces a new mode to control gene expression that has been previously overlooked in genetic engineering.
Entre compensación y disponibilidad: a propósito de ciertos temas de la condición humana en Arendt y Marquard
Authors: Chamorro Alicia Nathalie 
Published: January 2016

<p>En el presente texto nos ocupamos de la condición antropológica del hombre<br />desde su ser finito; de esta manera, se analiza la propuesta del hombre como ser de compensaciones del filósofo Odo Marquad, y se analizan las posibilidades de la razón límite para captar un sentido finito que es propio de la condición humana, a decir de Arendt. El sujeto necesita narrarse, inventar historias, porque no existe un sentido absoluto y fuera del tiempo, por ende, se duplica en las narraciones para compensar tal nostalgia del absoluto. creamos ficciones y narrativas como forma de construir el sentido del mundo a través de la posibilidad. La intención final del texto es formular que solamente desde la razón límite, entendida como risa y llanto –expresiones de la racionalidad al topar con el límite de lo incompensable y lo contingente–, se logra el acercamiento más fundamental al deseo de pensar la experiencia de lo imprevisible y vulnerable.</p>
La dimensión subjetiva de la política en América Latina
Authors: Neto Aristinete Bernardes Oliveira 
Published: January 2016

<p>El título del trabajo La dimensión subjetiva de la política en América Latinatiene el propósito de despertar a primera vista dos preguntas fundamentales: ¿por qué América Latina? y ¿por qué la subjetividad? Son dos temas que provocan tanto prejuicios como curiosidades en el ámbito académico de la filosofía. La opción por América Latinasurgió de una experiencia personal como estudiante de filosofía. con frecuencia nos sentimos desafortunados al tratar de ajustar los conocimientos adquiridos con las realidades que nos afectan como ciudadanos. La vida académica, sin lugar a dudas, se llena de sentido cuando nos damos cuenta de que es posible llevar al ámbito académico aquellos fantasmas que nos quedan en la mente, abstraídos de las crudas y sanguinarias imágenes de terror que encontramos a lo largo del continente. A través del estudio de la filosofía podemos pensar y soñar en nuevas sociedades humanas. En fin, me decidí por América Latina, porque aquí está mi destino.</p>