bluuebunny/crossref_metadata_2025_split huggingface dataset:
A transcriptome and literature guided algorithm for reconstruction of pathways to assess activity of telomere maintenance mechanisms
Authors: Nersisyan Lilit , Arakelyan Arsen 
Published: October 2017

AbstractActivation of telomere maintenance mechanisms (TMMs) is a crucial factor for indefinite proliferation of cancer cells. The most common TMM is based on the action of telomerase, but in some cancers telomeres are elongated via homologous recombination based alternative mechanism (ALT). Despite their importance, little is known about TMM regulation and factors responsible for TMM phenotype choice in different cells. Currently, many studies address the involvement of few genes in TMMs, but a consensus unified picture of the full process is missing.We have developed a computational biology framework combining knowledge- and data-driven approaches to aid in understanding of TMMs. It is based on a greedy algorithm with three core modules: (1) knowledge-based construction/modification of molecular pathways for telomerase-dependent and alternative TMMs, (2) coupled with gene expression data-based validation with an in-house pathway signal flow (PSF) algorithm, and (3) iteration of these two coupled steps until converging at pathway topologies that best reflect state of the art knowledge and are in maximum accordance with the data. We have used gene expression data derived from cell lines and tumor tissues and have performed extensive literature search and multiple cycles of greedy iterations until reaching TMM assessment accuracy of 100% and 77%, respectively.Availability of TMM pathways that best reflect recent knowledge and data will facilitate better understanding of TMM processes. As novel experimental findings in TMM biology emerge, and new datasets are generated, our approach may be used to further expand/improve the pathways, possibly allowing for making distinctions not only between telomerase-dependent and ALT TMMs, but also among their different subtypes. Moreover, this method may be used for assessment of TMM phenotypes from gene expression data, which is crucial for studies where experimental detection of TMM states is missing. Furthermore, it can also be used to assess TMM activities in proliferating healthy cells.
Young construction workers: substance use, mental health, and workplace psychosocial factors
Authors: Pidd Ken , Duraisingam Vinita , Roche Ann , Trifonoff Allan 
Published: October 2017

Purpose
Young Australian workers are at elevated risk of mental health and alcohol and other drug related problems. The purpose of this paper is to examine the relationship between alcohol and drug (AOD) use, psychological wellbeing, and the workplace psychosocial environment among young apprentices in the construction industry.

Design/methodology/approach
A cross-sectional survey of a cohort of 169 construction industry apprentices in their first year of training was undertaken. The survey included measures of psychological distress (K10), quantity/frequency measures of alcohol and illicit drug use, and workplace psychosocial factors.

Findings
Construction industry apprentices are at elevated risk of AOD related harm and poor mental health. Levels of psychological distress and substance use were substantially higher than age/gender equivalent Australian population norms. Job stress, workplace bullying, and general social support accounted for 38.2 per cent of the variance in psychological distress. General social support moderated the effects of job stress and bullying on psychological distress. Substance use was not associated with psychological distress. However, workplace social support accounted for 2.1 per cent of the variance in AUDIT-C scores, and 2.0 per cent of the variance in cannabis use. Workplace bullying explained 2.4 per cent of the variance in meth/amphetamine use.

Practical implications
Construction trades apprentices are a high-risk group for harmful substance use and poor mental health. Study results indicate that psychosocial wellbeing interventions are warranted as a harm reduction strategy.

Originality/value
This is the first study of its kind to describe a cohort of Australian construction trade apprentices in terms of their substance use and psychological wellbeing. The study shows workplace psychosocial factors may predict young workers psychological wellbeing.
Gender roles and customer organisational citizenship behaviour in emerging markets
Authors: Ho Jessica Sze Yin , Gaur Sanjaya S. , Chew Kok Wai , Khan Nasreen 
Published: October 2017

PurposeOrganisational citizenship behaviour (OCB) entails employees’ voluntary commitment to an organisation beyond their contractual responsibilities and has been found to be contributing to an organisation’s success. While the roles of gender and OCB exhibited by employees (as internal stakeholders) are documented, the role of gender in OCB by customers (as external stakeholders) of an organisation, especially within the context of emerging markets, is not found, therefore necessitating further studies. This research aims at bridging this research gap.Design/methodology/approachIn total, 203 male and 194 female customers representing the young working professionals segment rated their level of satisfaction with the relationship that they had with their banking website. They also indicated their willingness to participate in different dimensions of OCB.FindingsGenerally, both men and women, who are satisfied with the relationship that they have with the organisation, indicated their willingness to contribute to the organisation by displaying OCB. Contrary to past studies, where women at workplace were reported to be more likely to participate in OCB, the findings from the customer’s perspective revealed that men are more likely to engage in OCB.Research limitations/implicationsThe results indicated that OCB is not limited to internal customers (employees) but could also be expanded to external customers. The stereotypes causing females to be perceived as stronger OCB contributors may not remain constant in all types of circumstances.Originality/valueTo the best of the authors’ knowledge, this appears to be the first study to establish the gender role in OCB from the customer’s perspective in the context of an emerging market.
An investigation of gender and generational differences in attitudes toward the importance of a college degree in the UAE
Authors: Matherly Laura L. , Al Nahyan Sheikha Shamma bint Sultan bin Khalifa , Amin Nadia 
Published: October 2017

Purpose
This study examines attitudes toward higher education for men and women among male and female students and parents in the United Arab Emirates (UAE) and demonstrates gender differences in parent and student expectations about the importance of higher education.

Design/methodology/approach
This quantitative study examines attitudes toward higher education among 461 matched students and parents (total sample size 1442 respondents) in six higher education institutions in the United Arab Emirates (UAE) and demonstrates gender differences between parent and student perceptions.

Findings
In general, attitudes about the importance of a college degree were high and stable, except that younger, more recent female graduates were more likely to disagree that family traditions were threatened by women completing a college degree. Socio-demographic variables were associated with more favorable attitudes about the value of education for global leadership, the importance of a college education for both men and women and gender equality.

Research limitations/implications
Six higher education institutions were represented in the sample so external validity can be improved by studying these variables in other sample groups across the nation, region and globe. In addition, including additional types of universities, e.g. distance learning, technical, research and military, would indicate if the findings are generalizable to a broader range of institutions of higher education. There are opportunities for future comparative studies to examine the relevance of these findings across cultures and government initiatives to build national human resource capital and to consider other aspects of intergenerational relationships, attitudes and behaviors.

Originality/value
The authors examine perceived implications of the value of higher education on different arenas of men and women’s lives among the Emirates. Additionally, we focus on whether their attitudes vary by gender and generation.
Feminizing leadership in the Middle East
Authors: Shaya Nessrin , Abu Khait Rawan 
Published: October 2017

Purpose
This paper aims to form an empirical study, stemming from a Middle-Eastern context, on eliminating gender discrimination and achieving women’s empowerment. It aims to develop a conceptual model on the principal social and cultural factors inducing the success of Emirati women in attaining senior leadership roles and shaping their leadership style to be transformational. Moreover, it examines the comparability and divergence of the accumulated data on the empowerment of Emirati women in an international context from existing international literature.

Design/methodology/approach
The design of the study was based on data gathered from face-to-face, semi-structured interviews with four Emirati women occupying the highest leadership positions in various fields, followed by thematic analysis.

Findings
Data analysis confirmed the significant influence of the study’s key factors, namely, the role of the national government, Islamic work ethic and family, on the subjects’ empowerment and their adherence to transformational leadership style. However, two new k ey factors impacting empowerment emerged, namely, the influence of rulers’ leadership and the efforts in balancing work/life commitments. The findings led to the development of a study model on Emirati women empowerment and leadership style, reflecting the appropriateness of international literature on the Emirati context. Particularly, it is the social and economic circumstances of the nation supported by policies form the major source of empowerment, in addition to the important role that family capital and business ethics play. Remarkably, the challenges facing Emirati working women ought to be different than the rest of the Middle East.

Originality/value
A dearth of literature pertaining to women’s leadership exists; however, they were mostly carried out within Western contexts that may not be applicable to Arab societies because of cultural and religious differences. The study strives to portray an unambiguous picture to the significant impact of the parenting role and Islam work ethics in relating positively to their daughters and prompt them to develop crucial societal and professional skills, in a country as UAE where expatriates and Westerns dominate the population body. In addition, it shapes the UAE national government as a unique example and role model, to local governments in other Arab states, to learn from regarding supporting women, helping them to achieve excellence. Aiming for feminizing leadership, the Emirati women leadership styles are explored in an attempt to demonstrate the capacities and potentials of Emirati and Arab women in positions of power and influence. It is assumed that this study will help in bringing confidence in Emirati women capabilities, inducing a change in attitudes towards Arab women managers and encouraging employment in non-traditional feminine based jobs.
Agent model for multi-UAV control via protocol designs
Authors: Huang Sunan , Teo Swee Huat Rodney , Liu Wenqi , Dymkou Siarhei Michailovich 
Published: October 2017

Purpose
Cooperative control of a group of unmanned aerial vehicles (UAVs) is an important area of research. The purpose of this paper is to explore multi-UAV control in the framework of providing surveillance of areas of interest with automatic loss detection and replacement capabilities.

Design/methodology/approach
The research is based on the concept of the multi-agent system. The authors present the framework of the multi-agent and protocol design for monitoring the network of a group of UAVs.

Findings
If one or more UAVs which is conducting a high priority surveillance task is lost, the system can self-arrange for another UAV to replace the lost UAV and continue to execute its task. This research provides an excellent design protocol for UAV loss detection and replacement scheme.

Research limitations/implications
One of the major limitations of this research is that we have only two types of priority levels, high or low. If the priority is more than two levels, for example, high priority 1, high priority 2, or high priority 3, the replacement has not yet been implemented.

Originality/value
This paper contributes to the following two aspects of the scientific knowledge. The first contribution is the design of an agent model which jointly considers system architecture, communication, control logic and target monitoring. The second contribution includes the decentralized and automatic UAV loss detection and replacement algorithm.
Formulating layered adjustable autonomy for unmanned aerial vehicles
Authors: Mostafa Salama A. , Ahmad Mohd Sharifuddin , Mustapha Aida , Mohammed Mazin Abed 
Published: October 2017

Purpose
The purpose of this paper is to propose a layered adjustable autonomy (LAA) as a dynamically adjustable autonomy model for a multi-agent system. It is mainly used to efficiently manage humans’ and agents’ shared control of autonomous systems and maintain humans’ global control over the agents.

Design/methodology/approach
The authors apply the LAA model in an agent-based autonomous unmanned aerial vehicle (UAV) system. The UAV system implementation consists of two parts: software and hardware. The software part represents the controller and the cognitive, and the hardware represents the computing machinery and the actuator of the UAV system. The UAV system performs three experimental scenarios of dance, surveillance and search missions. The selected scenarios demonstrate different behaviors in order to create a suitable test plan and ensure significant results.

Findings
The results of the UAV system tests prove that segregating the autonomy of a system as multi-dimensional and adjustable layers enables humans and/or agents to perform actions at convenient autonomy levels. Hence, reducing the adjustable autonomy drawbacks of constraining the autonomy of the agents, increasing humans’ workload and exposing the system to disturbances.

Originality/value
The application of the LAA model in a UAV manifests the significance of implementing dynamic adjustable autonomy. Assessing the autonomy within three phases of agents run cycle (task-selection, actions-selection and actions-execution) is an original idea that aims to direct agents’ autonomy toward performance competency. The agents’ abilities are well exploited when an incompetent agent switches with a more competent one.
Motion control design for unmanned ground vehicle in dynamic environment using intelligent controller
Authors: Almayyahi Auday , Wang Weiji , Hussein Alaa Adnan , Birch Phil 
Published: October 2017

Purpose
The motion control of unmanned ground vehicles (UGV) is a challenge in the industry of automation. The purpose of this paper is to propose a fuzzy inference system (FIS) based on sensory information for solving the navigation challenge of UGV in cluttered and dynamic environments.

Design/methodology/approach
The representation of the dynamic environment is a key element for the operational field and for the testing of the robotic navigation system. If dynamic obstacles move randomly in the operation field, the navigation problem becomes more complicated due to the coordination of the elements for accurate navigation and collision-free path within the environmental representations. This paper considers the construction of the FIS, which consists of two controllers. The first controller uses three sensors based on the obstacles distances from the front, right and left. The second controller employs the angle difference between the heading of the vehicle and the targeted angle to obtain the optimal route based on the environment and reach the desired destination with minimal running power and delay. The proposed design shows an efficient navigation strategy that overcomes the current navigation challenges in dynamic environments.

Findings
Experimental analyses are conducted for three different scenarios to investigate the validation and effectiveness of the introduced controllers based on the FIS. The reported simulation results are obtained using MATLAB software package. The results show that the controllers of the FIS consistently perform the manoeuvring task and manage the route plan efficiently, even in a complex environment that is populated with dynamic obstacles. The paper demonstrates that the destination was reached optimally using the shortest free route.

Research limitations/implications
The paper represents efforts toward building a dynamic environment filled with dynamic obstacles that move at various speeds and directions. The methodology of designing the FIS is accomplished to guide the UGV to the desired destination while avoiding collisions with obstacles. However, the methodology is approached using two-dimensional analyses. Hence, the paper suggests several extensions and variations to develop a three-dimensional strategy for further improvement.

Originality/value
This paper presents the design of a FIS and its characterizations in dynamic environments, specifically for obstacles that move at different velocities. This facilitates an improved functionality of the operation of UGV.
“Impact”, research and slaying Zombies: the pressures and possibilities of the REF
Authors: MacDonald Robert 
Published: October 2017

Purpose
The purpose of this paper is to reflect critically upon current debates and tensions in the governance of research in the UK and more widely, particularly the imperative that social science research should demonstrate impact beyond the academy.

Design/methodology/approach
Drawing implicitly upon the Bevir’s theory of governance, the paper positions discourses about “research excellence and research impact” as elite narratives that are rooted genealogically in forms of managerial audit culture which seek to govern the practices of social science academics. The paper reviews relevant literature, draws upon key contributions that have shaped debate and refers to the author’s own research and experiences of “research impact”.

Findings
Initiatives such as the UK’s “Research Excellence Framework” can be understood as a form of governance that further enables already present neo-liberalising tendencies in the academy. The “impact agenda” has both negative (e.g. it can distort research priorities and can lead to overstatement of “real world” effects) and positive potential (e.g. to provide institutional space for work towards social justice, in line with long-standing traditions of critical social science and “public sociology”).

Research limitations/implications
There is a need for more critical research and theoretical reflection on the value, threats, limitations and potential of current forms of research governance and “impact”.

Originality/value
To date, there are very few article-length, critical discussions of these developments and issues in research governance, even fewer that connect these debates to longer-standing radical imperatives in social science.
“The way things get done around here…” Exploring spatial biographies, social policy and governance in the North East of England
Authors: Warren Jon 
Published: October 2017

Purpose
The purpose of this paper is to argue that the application of social policy in the North East of England is often characterised by tension and conflict. The agencies and professionals charged with implementation of Westminster driven policies constantly seek to deploy their knowledge of local conditions in order to make them both practical and palatable.

Design/methodology/approach
This paper examines the region via established literature from history, geography, sociology and social policy. The paper gives illustrations via empirical work which has evaluated initiatives to improve the health of long term health-related benefit recipients and to sustain individuals in employment in the region.

Findings
Central to the paper’s argument is the notion of “biographies of place”. The core of this idea is that places have biographies in the same way as individuals and possess specific identities. These biographies have been shaped by the intersections between environment, history, culture and economic and social policy. The paper identifies the region’s economic development, subsequent decline and the alliance of labour politics and industrial employers around a common consensus that sought economic prosperity and social progress via a vision of “modernisation” as a key component of this biography.

Originality/value
The paper argues that an appreciation of these spatial biographies can result in innovative and more effective social policy interventions with the potential to address issues that affect entire localities.
Bibliometric analysis of “Internet-plus”
Authors: Xie Hualing , Wang Shengtao , Chen Xiaoli , Wu Jingjing 
Published: October 2017

PurposeThe purpose of this paper is to gain an understanding of the current research on Internet-plus.Design/methodology/approachThe authors collected scholarly publications from the scientific databases Web of Science, Core Collection, Inspec and Compendex (Ei Village 2) and performed statistical analysis of the retrieved data from five perspectives.FindingsThe research on Internet-plus has obtained increasing attention in China. The top three research fields were social science, education and management.Originality/valueThe study will help researchers understand the current trends on Internet-plus.
Knowing and improving paraphrasing skills of Mexican college students
Authors: Cortes-Vera Jesus , Garcia Thelma J. , Gutierrez Alan 
Published: October 2017

Purpose
This study aims to develop both an activity and an instrument to support college students’ learning of the proper ways to paraphrase.

Design/methodology/approach
This study used a participatory action research approach, consisting of four phases. A survey was used to collect information, as well as a rubric to evaluate students’ competencies in paraphrasing, before and after an educational intervention activity. The tools were designed by the authors.

Findings
The findings suggest that students only have a partial understanding of the elements that are needed to write an adequate paraphrase, despite the declared importance in academic dialogue by the majority of them. The findings also suggest that a short-range intervention can help students develop their skills in paraphrasing.

Research limitations/implications
This research was conducted mostly with a small group of first-year college students and a professor they have known for a year. Therefore, a level of trust had been established. This trust relationship is necessary to achieve a participatory action in an unscheduled activity. Only some of the major results are presented.

Originality/value
Little actual research has been conducted on college students’ perception on paraphrasing and its importance, as well as on their abilities to paraphrase, especially in the Latin American context. This study demonstrates the usefulness of a short-range intervention that can be easily applied in any course or information literacy program.