bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aberrant growth and expansion in Penium margaritaceum triggered by disruption of microtubules and the cell wall
Authors: LoRicco Josephine G , Malone Stuart , Becker Abigail , Xue Nichole , Bagdan Kaylee , Eastman Anika , Sgambettera Gabriel , Winegrad Aaron , Gibeau Benjamin , Bauer Lindsay , Epstein Ruby , Domozych David S 
Published: September 2024

Abstract
Penium margaritaceum, a unicellular zygnematophyte (Streptophyta), was employed to elucidate changes in cell expansion when cells were challenged with the fungal pectinolytic enzyme, pectate lyase, and/or the microtubule-disrupting agent, amiprophos-methyl (APM). Microtubule disruption by APM resulted in significant swelling at expansion zones. These swollen zones provided an easy marker for the location of expansion zones, particularly in cells with altered cell wall pectin. Short-term treatment with pectate lyase showed pectin degradation primarily at the isthmus expansion zone and two satellite bands, corresponding to the location of future expansion in daughter cells. When the homogalacturonan lattice of the cell wall was removed by treatment with pectate lyase during long treatments, cell division was maintained, but daughter cell products were considerably smaller. Treatment of cells with a mixture of both pectate lyase and APM resulted in a distinct phenotype, consisting of ‘dumbbell’-shaped cells, as APM-induced swelling occurs at the novel expansion centers exposed by pectate lyase treatment. These cells also presented other curious alterations, including an extensive, chloroplast-free cytoplasmic zone at the center of the cell, a septum containing β-glycan, arabinogalactan and homogalacturonan epitopes, unique stacks of endoplasmic reticulum, displaced Golgi bodies, and an extensive network of vacuoles. These results provide insight into the importance of cell wall integrity in defining the location of cell growth and division in P. margaritaceum. Understanding these processes in a unicellular zygnematophyte may provide insights into steps involved in the evolution of land plants.
Disrupted oxylipin biosynthesis mitigates pathogen infections and pest infestations in cotton (Gossypium hirsutum)
Authors: McGarry Róisín C , Lin Yen-Tung , Kaur Harmanpreet , Higgs Harrison , Arias-Gaguancela Omar , Ayre Brian G 
Published: September 2024

Abstract
Cotton (Gossypium hirsutum) is the world’s most important fiber crop, critical to global textile industries and agricultural economies. However, cotton yield and harvest quality are undermined by the challenges introduced from invading pathogens and pests. Plant-synthesized oxylipins, specifically 9-hydroxy fatty acids resulting from 9-lipoxygenase activity (9-LOX), enhance the growth and development of many microbes and pests. We hypothesized that targeted disruption of 9-LOX-encoding genes in cotton could bolster crop resilience against prominent agronomic threats. Fusarium oxysporum f. sp. vasinfectum (FOV), Aphis gossypii (cotton aphid), and tobacco rattle virus induced the expression of 9-oxylipin biosynthesis genes, suggesting that the 9-LOX gene products were susceptibility factors to these stressors. Transiently disrupting the expression of the 9-LOX-encoding genes by virus-induced gene silencing significantly reduced target transcript accumulation, and this correlated with impaired progression of FOV infections and a significant decrease in the fecundity of cotton aphids. These findings emphasize that the cotton 9-LOX-derived oxylipins are leveraged by multiple pathogens and pests to enhance their virulence in cotton, and reducing the expression of 9-LOX-encoding genes can benefit cotton crop vitality.
The Concept of Transnational Law of Renewable Energy
Authors: Sourgens Frédéric G , Baldwin Edward , Banet Catherine 
Published: September 2024

Abstract
This chapter explores the challenges outlined by the first global stocktake under the Paris Agreement, emphasizing the need for a cooperative global effort guided by transparent norms to increase renewable energy projects significantly worldwide. It looks at the development and codification of transnational law for renewable energy through governance, financing, and legal complexities. It also highlights the importance of overcoming challenges, such as techno-nationalism and high capital costs, and describes the legal framework’s role in derisking projects. The chapter considers the changing geopolitical landscape and its impact on the global energy order and renewable energy development. It stresses the need for transnational law on renewable energy in the face of deglobalization and shifting global security, energy, and climate orders.
What Is ‘Renewable Energy’?
Authors: Sourgens Frédéric G , Baldwin Edward , Banet Catherine 
Published: September 2024

Abstract
This chapter reviews the definitions surrounding renewable energy, considering its position in relation to traditional energy sources like fossil fuels and nuclear energy. It discusses the role of renewable energy in reducing carbon dependency in energy generation. It also covers the regulatory implications of natural resources and land ownership, which can vary depending on the energy source. The chapter introduces solar power, wind power, and hydro power as the primary forms of renewable energy, outlining their markets and key players. It describes the diverse sizes, locations, and decentralized nature of renewable energy projects and analyses the need for energy systems and regulations to adapt to new technologies and relationships.
Renewable Energy and Sustainable Development Regimes
Authors: Sourgens Frédéric G , Baldwin Edward , Banet Catherine 
Published: September 2024

Abstract
This chapter delves into the intersection of renewable energy projects with sustainable development and explains the rationale behind states’ support for renewable energy projects and the legal frameworks that support such projects. It connects renewable energy projects to the broader discourse on sustainable development, highlighting how they contribute to meeting current economic, social, and cultural needs without compromising the environment for future generations. It also discusses how sustainable development is intertwined with human rights law, particularly the International Covenant on Economic, Social and Cultural Rights and the U.N. Convention on the Right to Development. The chapter highlights the importance of renewable energy in addressing climate change and energy poverty globally. It also explores the role of renewable energy in enhancing energy security and how the right to development can guide the implementation of renewable energy projects in a manner that is consistent with sustainable development goals.
Human Rights, Community Development, and Renewable Energy Projects
Authors: Sourgens Frédéric G , Baldwin Edward , Banet Catherine 
Published: September 2024

Abstract
This chapter addresses the social and environmental impacts of renewable energy projects, focusing on project site impacts and supply chain management. It highlights the importance of community development agreements in managing project risks and discusses the environmental and human rights impacts of supply chains. It also explains the legal obligations of renewable energy companies in managing impacts, both in the host state of the project and in their home jurisdiction. The chapter explores transnational legal regimes and their role in regulating companies’ operations. It stresses the significance of obtaining a social licence to operate, as failure to do so can lead to operational challenges and legal risks.
God-Talk: an Introduction
Authors: Novak David 
Published: September 2024

Abstract
God-talk consists of God speaking to humans in revelation, and humans speaking to God in prayer. They are the two forms of the covenantal language spoken between God and humans in general, and specifically between God and the Jewish people. God-talk is an essential component of the languages of all historic cultures. Yet there have been attempts to dismiss God-talk from public discourse, either epistemologically by claiming it is nonsense, or psychologically by claiming it is an invented illusion. Conversely, it is argued here that Jewish God-talk (by no means uniquely) has a logic that regulates how it may and may not be intelligently spoken by its speakers; hence it is not nonsense. And it is argued here that God-talk has always been spoken in human history, that it would be unintelligible in any language whose speakers did not already intend a real referent by the name “God”; hence it is not an invented illusion. This essay is an attempt to retrieve God-talk so that it can be conducted in public discourse, even in secular space.
Martin Buber’s Small Theological–Political Tractate The Question to the Single One as a Call for Intersubjective Action
Authors: Cherniak Yael 
Published: September 2024

Abstract
Martin Buber saw The Question to the Single One (his small theological–political tractate) as an addition that completed his dialogical work I and Thou by broadening dialogical thought to the theological–political–social level. This article presents new findings regarding the tractate’s composition. Furthermore, it delves into the concealed depth of meaning behind Buber’s argument with Søren Kierkegaard which is revealed from within the historical context of Nazi Germany. Indeed, the work is a brave and daring call to the German Christian as a single one standing before God, rousing him to behave in the intersubjective realm according to his obligation to social–political responsibility in response to God’s command. The ethical meaning deviates here from the historical: it constitutes a timeless call for action and responsible theo-political behavior on the social–political plane, which is relevant to our time; an ethical relationship with every other person, and deciding in favor of truth, even at the cost of opposing one’s own collective.
Identifying activity induced RV periodicities and correlations using central line moments
Authors: Barnes J R , Jeffers S V , Haswell C A , Damasso M , Del Sordo F , Liebing F , Perger M , Anglada-Escudé G 
Published: September 2024

ABSTRACT
The radial velocity (RV) method of exoplanet detection requires mitigation of nuisance signals arising from stellar activity. Using analytic cool and facular spot models, we explore the use of central line moments (CLMs) for recovering and monitoring rotation induced RV variability. Different spot distribution patterns, photosphere-spot contrast ratios, and the presence or absence of the convective blueshift lead to differences in CLM signals between M and G dwarfs. Harmonics of the rotation period are often recovered with the highest power in standard periodogram analyses. By contrast, we show the true stellar rotation may be more reliably recovered with string length minimization. For solar minimum activity levels, recovery of the stellar rotation signal from CLMs is found to require unfeasibly high signal-to-noise observations. The stellar rotation period can be recovered at solar maximum activity levels from CLMs for reasonable cross-correlation function (CCF) signal-to-noise ratios &gt;1000–5000. The CLMs can be used to recover and monitor stellar activity through their mutual correlations and correlations with RV and bisector inverse span. The skewness of a CCF, a measure of asymmetry, is described by the third CLM, $M_3$. Our noise-free simulations indicate the linear RV versus $M_3$ correlation is up to 10 per cent higher than the RV versus bisector inverse span correlation. We find a corresponding ∼5 per cent increase in linear correlation for CARMENES observations of the M star, AU Mic. We also assess the effectiveness of the time derivative of the second CLM, $M_2$, for monitoring stellar activity.
Acquiring the Lefschetz thimbles: efficient evaluation of the diffraction integral for lensing in wave optics
Authors: Shi Xun 
Published: September 2024

ABSTRACT
Evaluating the Kirchhoff–Fresnel diffraction integral is essential in studying wave effects in astrophysical lensing, but is often intractable because of the highly oscillatory integrand. A recent breakthrough was made by exploiting the Picard–Lefschetz theory: the integral can be performed along the ‘Lefschetz thimbles’ in the complex domain where the integrand is not oscillatory but rapidly converging. The application of this method, however, has been limited by both the unfamiliar concepts involved and the low numerical efficiency of the method used to find the Lefschetz thimbles. In this paper, we give simple examples of the Lefschetz thimbles and define the ‘flow lines’ that facilitate the understanding of the concepts. Based on this, we propose new ways to obtain the Lefschetz thimbles with high numerical efficiency, which provide an effective tool for studying wave effects in astrophysical lensing.
Simulating stellar coronal rain and slingshot prominences
Authors: Daley-Yates S , Jardine Moira M 
Published: September 2024

ABSTRACT
We have numerically demonstrated that simulated cool star coronae naturally form condensations. If the star rotates slowly, with a co-rotation radius greater than the Alfvén radius (i.e. $R_{\mathrm{K}} \gt R_{\mathrm{A}}$), these condensations will form below the co-rotation radius $R_{\mathrm{K}}$ and simply fall back to the stellar surface as coronal rain. If, however, the star is more rapidly rotating, ($R_{\mathrm{K}} \lt R_{\mathrm{A}}$), not only rain will form but also ‘slingshot prominences’. In this case, condensations collect into a large mass reservoir around the co-rotation radius, from which periodic centrifugal ejections occur. In this case, some 51 per cent of the coronal mass is cold gas, either in rain or prominences. We find that 21 per cent of the mass lost by our simulated fast rotating star is cold gas. Studies of stellar mass-loss from the hot wind do not consider this component of the wind and therefore systematically underestimate mass-loss rates of these stars. Centrifugal ejections happen periodically, between every 7.5–17.5 h with masses clustering around $10^{16}$ g, These results agree well with observational statistics. Contrasting the fast and slow rotating magnetospheres, we find that there are two distinct types of solutions, high-lying and low-lying loops. Low-lying loops only produce coronal rain whereas high-lying loops produce both rain and slingshots.
Regulating star formation in a magnetized disc galaxy
Authors: Robinson Hector , Wadsley James 
Published: September 2024

ABSTRACT
We use high-resolution magnetohydrodynamic simulations of isolated disc galaxies to investigate the co-evolution of magnetic fields with a self-regulated, star-forming interstellar medium (ISM). The simulations are conducted using the ramses adaptive mesh refinement code on the standard agora initial condition, with gas cooling, star formation, and feedback. We run galaxies with a variety of initial magnetic field strengths. The fields evolve and achieve approximate saturation within 500 Myr, but at different levels. The galaxies reach a quasi-steady state, with slowly declining star formation due to both gas consumption and increase in the field strength at intermediate ISM densities. We connect this behaviour to differences in the gas properties and overall structure of the galaxies. Stronger magnetic fields limit supernova bubble sizes. Different cases support the ISM using varying combinations of magnetic pressure, turbulence, and thermal energy. Initially, $\gtrsim\!\! 1\ \mu \mathrm{ G}$ magnetic fields evolve modestly and dominate support at all radii. Conversely, initially weaker fields grow through feedback and turbulence but never dominate the support. This is reflected in the stability of the gas disc. This interplay determines the overall distribution of star formation in each case. We conclude that an initially weak field can grow to produce a realistic model of a local disc galaxy, but starting with typically assumed field strengths ($\gtrsim\!\! 1\ \mu \mathrm{ G}$) will not.
Validating full-spectrum fitting with a synthetic integral-field spectroscopic observation of the Milky Way
Authors: Wang Zixian , Sharma Sanjib , Hayden Michael R , van de Sande Jesse , Bland-Hawthorn Joss , Vaughan Sam , Martig Marie , Pinna Francesca 
Published: September 2024

ABSTRACT
Ongoing deep integral-field spectroscopy (IFS) observations of disc galaxies provide opportunities for comparison with the Milky Way (MW) to understand galaxy evolution. However, such comparisons are marred by many challenges such as selection effects, differences in observations and methodology, and proper validation of full-spectrum fitting methods. In this study, we present a novel code GalCraft to address these challenges by generating mock IFS data cubes of the MW using simple stellar population models and a mock MW stellar catalogue derived from E-galaxia. We use the widely adopted full-spectrum fitting code ppxf to investigate the ability to recover kinematics and stellar populations for an edge-on mock MW IFS observation. We confirm that differences in kinematics, mean age, $[\mathrm{M/H}]$, and $[\mathrm{\alpha /Fe}]$ between thin and thick discs can be distinguished. However, the age distribution is overestimated in the ranges between $2{-}4$ and $12{-}14$ Gyr compared to the expected values. This is likely due to the age spacing and degeneracy of SSP templates. We find systematic offsets in the recovered kinematics due to insufficient spectral resolution and the variation of line-of-sight velocity distribution with age and $[\mathrm{M/H}]$. With future higher resolution and multi-$[\mathrm{\alpha /Fe}]$ simple stellar population templates, GalCraft will be useful to validate key signatures such as $[\mathrm{\alpha /Fe}]$–$[\mathrm{M/H}]$ distribution at different R and $|z|$ and potentially infer radial migration and kinematic heating efficiency to study detailed chemodynamical evolution of MW-like galaxies.
The Chromosome-level Genome Provides Insights into the Evolution and Adaptation of Extreme Aggression
Authors: Liu Peng-Cheng , Wang Zi-Yin , Qi Mei , Hu Hao-Yuan 
Published: September 2024

Abstract
Extremely aggressive behavior, as the special pattern, is rare in most species and characteristic as contestants severely injured or killed ending the combat. Current studies of extreme aggression are mainly from the perspectives of behavioral ecology and evolution, while lacked the aspects of molecular evolutionary biology. Here, a high-quality chromosome-level genome of the parasitoid Anastatus disparis was provided, in which the males exhibit extreme mate-competition aggression. The integrated multiomics analysis highlighted that neurotransmitter dopamine overexpression, energy metabolism (especially from lipid), and antibacterial activity are likely major aspects of evolutionary formation and adaptation for extreme aggression in A. disparis. Conclusively, our study provided new perspectives for molecular evolutionary studies of extreme aggression as well as a valuable genomic resource in Hymenoptera.
Nietzschean Perspectivism: Representation and Values
Authors: Anderson R Lanier 
Published: September 2024

ABSTRACT
Nietzsche’s perspectivism can fruitfully be understood as a claim that all our representations are perspectival and absolute representations are impossible. But that treatment leaves unclear another key aspect of Nietzschean perspectivism—the idea that our representations are perspectival because they are ultimately rooted in some way in our values. I motivate this latter aspect of Nietzsche’s account through an argument that relies on the contrast between Bernard Williams’s rejection of “external reasons statements” in the case of practical reasoning, and his reliance on an “absolute conception of the world” in theoretical reasoning. Nietzsche holds, by contrast, that theoretical reasoning, too, can offer only “internal,” and hence perspectival, reasons.
Was ist also Loben? Nietzsche on the Ethics of Praise
Authors: Lillehammer Hallvard 
Published: September 2024

Abstract
This paper explores the ethics of praise as discussed in the works of Friedrich Nietzsche. Nietzsche’s occasional remarks on praise are shown to be mainly critical, with his remarks falling into three broad categories, namely: i) metaphysical, ii) psychological, and iii) ethical. During the course of the paper, Nietzsche’s approach is located in the wider theoretical context of contemporary work on the ethics of praise and moral philosophy more generally.
Dionysian Religion and Socratic Philosophy in Nietzsche’s The Birth of Tragedy
Authors: Wood William 
Published: September 2024

ABSTRACT
In The Birth of Tragedy, Nietzsche contrasts the rationalism and optimism of Socrates with the tragic outlook of the “Dionysian Greeks.” Most scholars read him as taking the side of the Dionysian Greeks against Socrates. I argue that Nietzsche presents the Dionysian as an essentially religious perspective, characterized by a proto-Christian need for redemption or “metaphysical solace” he implicitly disavows. Nietzsche himself occupies a perspective which incorporates elements of the Dionysian and the Socratic and gestures towards a higher synthesis, which like Socratic philosophy is reflective and contemplative, delighting in the pursuit and enjoyment of knowledge, but like Dionysian wisdom acknowledges the limits of rationalism. This new philosophy is neither tragic nor optimistic but playful and comic or, perhaps, tragicomic.
A case of eosinophilic granulomatosis with polyangiitis preceded by allergic bullous lesions
Authors: Hasegawa Eiko , Iijima Momoko , Sekine Akinari , Inoue Noriko , Tanaka Kiho , Suwabe Tatsuya , Yamanouchi Masayuki , Oba Yuki , Kume Ayako , Kono Kei , Kinowaki Keiichi , Ohashi Kenichi , Yamaguchi Yutaka , Suyama Yasuhiro , Wada Takehiko , Sawa Naoki , Takahashi Kotono , Ueki Shigeharu , Ubara Yoshifumi 
Published: September 2024

ABSTRACT
A 62-year-old man with a history of diabetes mellitus was hospitalised with numbness of lower limbs, bullous lesions of the whole body, kidney dysfunction, presence of eosinophils, and elevated antineutrophil cytoplasmic antibodies to myeloperoxidase and anti-bullous pemphigoid 180 antibodies and was diagnosed with mononeuritis multiplex. Kidney and muscle biopsies showed vasculitis with fibrinoid necrosis, whereas skin biopsies showed only blister formation between the epidermis and dermis; a high eosinophilic infiltrate was present in all three tissues. These findings led to a diagnosis of eosinophilic granulomatosis with polyangiitis combined with allergic bullous lesions. Immunohistological examination indicated cytolytic eosinophils and extracellular traps, suggesting the presence of eosinophil extracellular trap cell death (eosinophil ETosis) in diseased tissue.
Plasma miR-122-5p and miR-142-5p and their role in chemoresistance of patients with colon cancer
Authors: Vokacova Klara , Landecka Aneta , Selvi Saba , Horak Josef , Novosadova Vendula , Manakova Katerina , Levy Miroslav , Vymetalkova Veronika 
Published: September 2024

Abstract
Chemoresistance represents a major issue affecting cancer therapy efficacy. Because microRNAs (miRNAs) regulate gene expression on multiple levels, their role in chemoresistance development is reasonably certain. In our previous study, miR-122-5p and miR-142-5p were identified as diagnostic, prognostic, and predictive biomarkers for primary and metastatic rectal cancer. The aim of the present study was to investigate whether these miRNAs can also reflect the disease course of patients with colon cancer (CC). Further, we focused on a deeper understanding of their involvement in 5-fluorouracil (5-FU) chemoresistance development.