bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Reactivity of 1,2,3‐Triazoles Towards Sulfonyl Chlorides. A Novel Approach to 1‐ and 2‐Sulfonyl‐4‐azolyl‐1,2,3‐triazoles.
Authors: Beryozkina Tetyana V. , et al.  
Published: November 2015

AbstractThe regioselectivity of the sulfonylation is mainly influenced by the nature of the aryl substituent at C‐4 and the bulkiness of the sulfonyl chloride.
ChemInform Abstract: Asymmetric Michael Addition/Intramolecular Cyclization Catalyzed by Bifunctional Tertiary Amine‐Squaramides: Construction of Chiral 2‐Amino‐4H‐chromene‐3‐carbonitrile Derivatives.
Authors: Gao Yu , Du Da‐Ming 
Published: November 2015

AbstractThe efficient asymmetric Michael addition/intramolecular cyclization of malononitrile with dienones catalyzed by a chiral bifunctional tertiary amine—squaramide catalyst for the synthesis of chiral 2‐amino‐4H‐chromene‐3‐carbonitrile derivatives is developed.
ChemInform Abstract: Synthetic and Structural Studies on Novel 4,3′‐Bicoumarins.
Authors: Pujar Kiran K. , Kulkarni Manohar V. , Alawandi Ganesh N. , Anilkumar G. N. , Basanagouda Mahantesha 
Published: November 2015

AbstractThe title coumarins are conveniently obtained by two methods either in the presence of piperidine or of sodium hydride.
ChemInform Abstract: Mild and Regioselective N‐Alkylation of 2‐Pyridones in Water.
Authors: Hao Xin , Xu Zhongmiao , Lu Hongfu , Dai Xuedong , Yang Ting , Lin Xichen , Ren Feng 
Published: November 2015

AbstractTween 20 is used to create a micellar system in the title reaction.
ChemInform Abstract: One‐Pot Synthesis of Quinolin‐4(1H)‐one Derivatives by a Sequential Michael Addition—Elimination/Palladium‐Catalyzed Buchwald—Hartwig Amination Reaction.
Authors: Wang Yinghua , Liang Hanyu , Chen Chunxia , Wang Deqiang , Peng Jinsong 
Published: November 2015

AbstractThe title synthesis uses chlorovinyl aromatic ketones [e.g. (I)] or bromovinyl aromatic ketones [e.g. (XIV)] and amines as starting material and the products can be obtained in good to excellent yields.
ChemInform Abstract: Coupling Cyclizations with Fragmentations for the Preparation of Heteroaromatics: Quinolines from O‐Alkenyl Arylisocyanides and Boronic Acids.
Authors: Evoniuk Christopher J. , Ly Michelle , Alabugin Igor V. 
Published: November 2015

AbstractStereoelectronic restrictions on homoallylic ring expansion in alkyne cascades can be overcome by use of alkenes as synthetic equivalents of alkynes in reaction cascades that are terminated by C—C bond fragmentation.
ChemInform Abstract: Graphene Oxide Nanosheets: A Highly Efficient and Reusable Carbocatalyst Catalyzes the Michael‐Cyclization Reactions of 4‐Hydroxycoumarins, 4‐Hydroxypyrone and 4‐Hydroxy‐1‐methylquinolinone with Chalcone Derivatives in Aqueous Media.
Authors: Kausar Nazia , Ghosh Partha Pratim , Pal Gargi , Das Asish R. 
Published: November 2015

AbstractA library of pyranoquinolines, pyranopyrans and 4H‐pyrans are synthesized from the title methods.
ChemInform Abstract: Ruthenium‐Catalyzed Oxidative C—H Bond Alkenylation of 2‐Phenylimidazo[1,2‐a]pyridine.
Authors: Sawant Devesh , Singh Iqubal , Tulsyan Gaurav , Abbagani Kishor , Pardasani Ram T. 
Published: November 2015

AbstractThe ruthenium‐catalyzed oxidative C—H bond alkenylation of 2‐phenylimidazo[1,2‐a]pyridine (I) with acrylates (II) affords regioselectively the corresponding ortho products (III).
ChemInform Abstract: Modular, Concise, and Efficient Synthesis of Highly Functionalized 5‐Fluoropyridazines by a [2 + 1]/[3 + 2]‐Cycloaddition Sequence.
Authors: Tran Gael , Gomez Pardo Domingo , Tsuchiya Tomoki , Hillebrand Stefan , Vors Jean‐Pierre , Cossy Janine 
Published: November 2015

AbstractThe [2+1] reaction of terminal alkynes [e.g. (I)] and difluorocarbene ([II] or [IX]) gives difluorocyclopropenes [e.g. (III)] which further go through [3 + 2]‐cycloaddition with diazo compounds [e.g. (IV)] to furnish fluoropyridazines [e.g. (VI)].
ChemInform Abstract: Substrate Directed C—H Activation for the Synthesis of Benzo[c]cinnolines Through a Sequential C—C and C—N Bond Formation.
Authors: Reddy B. V. Subba , Reddy C. Ravikumar , Reddy M. Rajashekhar , Yarlagadda Suresh , Sridhar B. 
Published: November 2015

AbstractThe novel strategy is based on an oxidative two‐step transformation of hydrazine dicarboxylates with aryl iodides.
ChemInform Abstract: C—C/C—N Cross‐Coupling Reactions of Aryl Sulfonates Catalyzed by an Eco‐Friendly and Reusable Heterogeneous Catalyst: Wool—Pd Complex.
Authors: Yang Quan‐Lu , Quan Zheng‐Jun , Du Bao‐Xin , Wu Shang , Zhang Yin‐Pan , Li Pei‐Dong , Wang Ming‐Ming , Lei Zi‐Qiang , Wang Xi‐Cun 
Published: November 2015

AbstractThe title reactions between substituted pyrimidin‐2‐yl sulfonates [e.g. (I)] and arylboronic acids, terminal alkynes, or anilines give the cross‐coupling products in good yields with wide substrate scope.
ChemInform Abstract: Efficient Multi‐Component Synthesis of 1,4‐Benzodiazepine‐3,5‐diones: A Petasis‐Based Approach.
Authors: Noushini Saeedeh , Mahdavi Mohammad , Firoozpour Loghman , Moghimi Setareh , Shafiee Abbas , Foroumadi Alireza 
Published: November 2015

AbstractThe one‐pot reaction between anthranilic acid amides (I), glyoxalic acid (II) and arylboronic acids (III) gives the title compounds in good yields.
ChemInform Abstract: A Simple and Green Procedure for the One‐Pot Synthesis of α‐Aminophosphonates with Quaternary Ammonium Salts as Efficient and Recyclable Reaction Media.
Authors: Yu Ya‐Qin , Xu Da‐Zhen 
Published: November 2015

Abstractα‐Aminophosphonates are obtained from aldehydes or ketones with amines and diethyl or triethyl phosphite in excellent yields at room temperature within short time.
ChemInform Abstract: (+)‐ and (‐)‐Spiroreticulatine, a Pair of Unusual Spiro Bisheterocyclic Quinoline‐imidazole Alkaloids from the South China Sea Sponge Fascaplysinopsis reticulata.
Authors: Wang Qi , Tang Xuli , Luo Xiangchao , de Voogd Nicole J. , Li Pinglin , Li Guoqiang 
Published: November 2015

AbstractThe title compounds [cf.
ChemInform Abstract: A General Method for N‐Glycosylation of Nucleobases Promoted by (p‐Tol)2SO/Tf2O with Thioglycoside as Donor.
Authors: Liu Guang‐jian , Zhang Xiao‐tai , Xing Guo‐wen 
Published: November 2015

AbstractBased on a preactivation strategy using the (p‐Tol)2SO/Tf2O system, a series of nucleosides are synthesized by coupling various thioglycosides such as (I), (IV), and (VII) with pyrimidine and purine bases.
ChemInform Abstract: A Multifunctional Nanocomposite of Magnetic γ‐Fe2O3 and Mesoporous Fluorescent ZnO.
Authors: Maiti Debabrata , Mukhopadhyay Soumita , Chandra Mohanta Subas , Saha Arindam , Sujatha Devi Parukuttyamma 
Published: November 2015

AbstractThe title nanocomposite is prepared by dispersing γ‐Fe2O3 and mesoporous ZnO in EtOH under sonication (250 W, 10 min) before mixing and refluxing (80 °C, 4 h).
ChemInform Abstract: Highly Efficient Red Phosphor Cs2GeF6:Mn4+for Warm White Light‐Eemitting Diodes.
Authors: Wang Zhengliang , Zhou Yayun , Liu Yong , Zhou Qiang , Luo Lijun , Tan Huiying , Zhang Qiuhan , Chen Guo , Peng Jinhui 
Published: November 2015

AbstractCs2GeF6:Mn4+ is prepared by cation exchange through addition of K2MnF6 and CsF to a GeO2 solution in HF (40 wt.%).
ChemInform Abstract: Core—Shell Nanoparticles: Synthesis and Applications in Catalysis and Electrocatalysis
Authors: Gawande Manoj B. , Goswami Anandarup , Asefa Tewodros , Guo Huizhang , Biradar Ankush V. , Peng Dong‐Liang , Zboril Radek , Varma Rajender S. 
Published: November 2015

AbstractReview: 476 refs.
ChemInform Abstract: Sol‐Gel Organic‐Inorganic Hybrid Materials Containing Lanthanide Complexes with Polydentate Acyclic and Cyclic Ligands: Synthesis and Spectral‐Luminescent Properties
Authors: Smola S. S. , Snurnikova O. V. , Fadeyev E. N. , Rusakova N. V. 
Published: November 2015

AbstractReview: 54 refs.
ChemInform Abstract: Core‐Structure‐Inspired Asymmetric Addition Reactions: Enantioselective Synthesis of Dihydrobenzoxazinone‐ and Dihydroquinazolinone‐Based anti‐HIV Agents
Authors: Li Shen , Ma Jun‐An 
Published: November 2015

AbstractReview: [overview of the asymmetric synthesis of dihydrobenzoxazinone‐ and dihydroquinazolinone‐based anti‐HIV agents.
ChemInform Abstract: Current Pretreatment Technologies for the Development of Cellulosic Ethanol and Biorefineries
Authors: Silveira Marcos Henrique Luciano , Morais Ana Rita C. , da Costa Lopes Andre M. , Olekszyszen Drielly Nayara , Bogel‐Lukasik Rafal , Andreaus Juergen , Pereira Ramos Luiz 
Published: November 2015

AbstractReview: [273 refs.
Double Asymmetric Induction During the Addition of (RP)‐Menthyl Phenyl Phosphine Oxide to Chiral Aldimines
Authors: Zhou Zhong‐Yang , Zhang He , Yao Lan , Wen Jing‐Hong , Nie Shao‐Zhen , Zhao Chang‐Qiu 
Published: November 2015

AbstractP,C‐Stereogenic α‐amino phosphine oxides were prepared from the addition of (RP)‐menthyl phenyl phosphine oxide to chiral aldimines under neat condition at 80 °C in up to 91:9 drC and 99% yields. The diastereoselectivity was mainly induced by chiral phosphorus that showed matched or mismatched induction with (S)‐ or (R)‐aldimines, respectively. Chirality 28:132–135, 2016. © 2015 Wiley Periodicals, Inc.
Design, Synthesis and Evaluation of Triazole‐Pyrimidine Analogues as SecA Inhibitors
Authors: Cui Jianmei , Jin Jinshan , Chaudhary Arpana Sagwal , Hsieh Ying‐hsin , Zhang Hao , Dai Chaofeng , Damera Krishna , Chen Weixuan , Tai Phang C. , Wang Binghe 
Published: November 2015

AbstractSecA, a key component of the bacterial Sec‐dependent secretion pathway, is an attractive target for the development of new antimicrobial agents. Through a combination of virtual screening and experimental exploration of the surrounding chemical space, we identified a hit bistriazole SecA inhibitor, SCA‐21, and studied a series of analogues by systematic dissections of the core scaffold. Evaluation of these analogues allowed us to establish an initial structure–activity relationship in SecA inhibition. The best compounds in this group are potent inhibitors of SecA‐dependent protein‐conducting channel activity and protein translocation activity at low‐ to sub‐micromolar concentrations. They also have minimal inhibitory concentration (MIC) values against various strains of bacteria that correlate well with the SecA and protein translocation inhibition data. These compounds are effective against methicillin‐resistant Staphylococcus aureus strains with various levels of efflux pump activity, indicating the capacity of SecA inhibitors to null the effect of multidrug resistance. Results from studies of drug‐affinity‐responsive target stability and protein pull‐down assays are consistent with SecA as a target for these compounds.
Inspired by Nature: The 3‐Halo‐4,5‐dihydroisoxazole Moiety as a Novel Molecular Warhead for the Design of Covalent Inhibitors
Authors: Pinto Andrea , Tamborini Lucia , Cullia Gregorio , Conti Paola , De Micheli Carlo 
Published: November 2015

AbstractOver the past few decades, there has been an increasing interest in the development of covalent enzyme inhibitors. As it was recently re‐emphasized, the selective, covalent binding of a drug to the desired target can increase efficiency and lower the inhibitor concentration required to achieve a therapeutic effect. In this context, the naturally occurring antibiotic acivicin, and in particular its 3‐chloro‐4,5‐dihydroisoxazole scaffold, has provided a wealth of inspiration to medicinal chemists and chemical biologists alike. In this Concept, to underline the great potentiality that the 3‐halo‐4,5‐dihydroisoxazole warhead has in drug discovery, we present a number of examples, grouped by their potential biological activity and targets, in which this scaffold has been fruitfully used to develop novel biologically active compounds. Through these examples, we show that the 3‐halo‐4,5‐dihydroisoxazole moiety represents an outstanding warhead with high potential for the design of novel covalent enzyme inhibitors.
Rapid Large‐Scale Synthesis of Vanadate Nanoscrolls with Controllable Lengths
Authors: Rostamzadeh Taha , Adireddy Shiva , Zhang Xiaodong , Koplitz Brent , Chrisey Douglas B. , Wiley John B. 
Published: November 2015

AbstractA simple one‐step solvothermal synthetic approach has been applied to the rapid fabrication of VOx nanoscrolls (NScs) from vanadium pentoxide and either dodecylamine or octadecylamine as the structure‐directing agent (SDA). By reaction of the appropriate ratio of SDA to vanadium oxide and solvent at 250 °C, approximately 20 g of NScs per synthesis could be formed within 2 h. Syntheses could be further adjusted so that the average lengths of the NScs could be varied from approximately 383 to 816 nm to 3.3 μm. The effect of synthesis parameters such as temperature, solvothermal reaction duration, and vanadium oxidation state on the formation of NScs was also investigated; detailed studies indicate that the variation between V4+ and V5+ appears to play a critical role in the formation of vanadate NScs.
Accelerating Asian option pricing on many‐core architectures
Authors: Li Shuo , Lin James 
Published: November 2015

SummaryIn this paper, we start by looking at the algorithms and the numerical methods of pricing one exotic option, the strong path dependent Asian option using the Black–Scholes pricing model. We cover both geometric average and arithmetic average schemes that lead us to two different numerical solutions. Next, we discuss how to implement these algorithms on the leading many‐core architectures with contrasting programming models and still achieve the comparable performance results. As an example, we will show that a 2‐year contract with 252 times steps and 1,000,000 samples can be priced in approximately one fifth of a second on two leading many‐core architectures. The purpose of this paper is to understand what is required to accelerate the numerical‐intensive algorithms such as the Asian option pricing algorithm in quantitative and how to take advantage of the parallel programming features on many‐core architecture and express parallelism inherent in the similar algorithms in quantitative finance. Copyright © 2015 John Wiley & Sons, Ltd.
Eating disorder examination: Factor structure and norms in a clinical female pediatric eating disorder sample
Authors: O'Brien Amy , Watson Hunna J. , Hoiles Kimberley J. , Egan Sarah J. , Anderson Rebecca A. , Hamilton Matthew J. , Shu Chloe , McCormack Julie 
Published: November 2015

ABSTRACTObjectiveThe factor structure of the eating disorder examination (EDE) has never been tested in a clinical pediatric sample, and no normative data exist.MethodThe factor structure of an adapted EDE was examined in a clinical sample of 665 females aged 9–17 years with anorexia nervosa spectrum (70%), bulimia nervosa spectrum (12%), purging disorder (3%), and unspecified feeding and eating disorders (15%).ResultsThe original four‐factor model was a good fit in a confirmatory factor analysis as well a higher order model with three dimensions of restraint, eating concern, and combined weight concern/shape concern. Normative data are reported for clinicians to identify the percentiles in which their patients' score.DiscussionThe findings support dimensions of restraint, eating concern, weight concern, and shape concern in a clinical pediatric sample. This supports the factorial validity of the EDE, and the norms may assist clinicians to evaluate symptoms in females under 18 years. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:107–110)
A preliminary evaluation of the validity of binge‐eating disorder defining features in a community‐based sample
Authors: Klein Kelly M. , Forney K. Jean , Keel Pamela K. 
Published: November 2015

ABSTRACTObjectiveLittle empirical attention has been paid to the DSM‐5 definition of binge‐eating disorder (BED), particularly to the associated features of binge episodes. The present study sought to determine how the associated features and undue influence of weight/shape on self‐evaluation contribute to evidence of a clinically significant eating disorder.MethodSecondary analyses were conducted on data (N = 80; 76.3% women, 76.3% Caucasian, ages 18–43) collected through an epidemiological study of eating patterns. Descriptive statistics were used to report the sample prevalence of the features, independently and in combination. Correlations and alpha reliability were employed to examine relationships among associated features, distress regarding bingeing, and clinical diagnosis. Regression models and receiver‐operating characteristic (ROC) curves were used to determine the utility of the features for explaining variance in distress.ResultsInternal consistency reliability for indicators was low, and several features demonstrated low or nonsignificant associations with distress and diagnosis. Feeling disgusted/depressed/guilty was the only unique predictor of distress (p = 0.001). For the ROC curves, three features was the best threshold for predicting distress.DiscussionResults support the need to refine the features to ensure better detection of clinically significant eating pathology for research inclusion and treatment of the illness. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:524–528).
Rapid and repeatable shifts in life‐history timing of Rhagoletis pomonella (Diptera: Tephritidae) following colonization of novel host plants in the Pacific Northwestern United States
Authors: Mattsson Monte , Hood Glen R. , Feder Jeffrey L. , Ruedas Luis A. 
Published: November 2015

AbstractHost shifts of phytophagous insect specialists to novel plants can result in divergent ecological adaptation, generating reproductive isolation and potentially new species. Rhagoletis pomonella fruit flies in eastern North America underwent a host shift ~160 ya from native downy hawthorn (Crataegus mollis) to introduced, domesticated apple (Malus domestica). Divergent selection on diapause phenology related to the earlier fruiting time of apples versus downy hawthorns resulted in partial allochronic reproductive isolation between the fly races. Here, we test for how rapid and repeatable shifts in life‐history timing are driving ecological divergence of R. pomonella in the Pacific Northwestern USA. The fly was introduced into the region via larval‐infested apples 40–65 ya and now attacks native black hawthorn (Crataegus douglasii) and introduced ornamental hawthorn (Crataegus monogyna), in addition to early‐ and late‐maturing apple varieties in the region. To investigate the life‐history timing hypothesis, we used a field‐based experiment to characterize the host‐associated eclosion and flight activity patterns of adults, and the feeding times of larvae at a field site in Vancouver, Washington. We also assessed the degree to which differences in host‐fruiting time generate allochronic isolation among apple‐, black hawthorn‐, and ornamental hawthorn‐associated fly populations. We conclude that host‐associated fly populations are temporally offset 24.4% to 92.6% in their seasonal distributions. Our results imply that R. pomonella possesses the capacity for rapid and repeatable shifts in diapause life history to match host‐fruiting phenology, which can generate ecologically based reproductive isolation, and potentially biodiversity in the process.
A dimensionless statistical analysis of logjam form and process
Authors: Dixon Simon James 
Published: November 2015

AbstractLarge wood in rivers and logjams are linked to the presence of varied riverine morphologies and increased abundance and diversity of aquatic biota. Current research into the ecohydrological, morphological and geochemical effects of logjams is restricted by difficulties in comparing findings between river systems. The problem is exacerbated by a lack of standardized metrics for recording and reporting logjams and a scale dependence of logjam effects with river size. In this paper, a new method for analysing logjams is presented based on a set of seven dimensionless metrics of structure and morphological effects. These metrics are used along with a cluster analysis to identify key logjam types within a study river. The analysis framework is applied to data from a small forest river in the UK and identifies that 73% of logjams in this system can be grouped into eight distinct classes. Of these classes, two are logjams that only partly fill the channel, and six are channel spanning. The individual classes are differentiated from each other principally by the degree of lateral and vertical erosions found in association with the logjams. The dimensionless metrics are also applied qualitatively to a range of logjams described in the literature and show the potential for the method to be applied as a standard survey and analysis framework for logjams across diverse river environments. The potential to link logjam form with function, and therefore provision of specific habitats, has wide applicability to the design and monitoring of river restoration schemes. Copyright © 2016 John Wiley & Sons, Ltd.
Personality and complex brain networks: The role of openness to experience in default network efficiency
Authors: Beaty Roger E. , Kaufman Scott Barry , Benedek Mathias , Jung Rex E. , Kenett Yoed N. , Jauk Emanuel , Neubauer Aljoscha C. , Silvia Paul J. 
Published: November 2015

AbstractThe brain's default network (DN) has been a topic of considerable empirical interest. In fMRI research, DN activity is associated with spontaneous and self‐generated cognition, such as mind‐wandering, episodic memory retrieval, future thinking, mental simulation, theory of mind reasoning, and creative cognition. Despite large literatures on developmental and disease‐related influences on the DN, surprisingly little is known about the factors that impact normal variation in DN functioning. Using structural equation modeling and graph theoretical analysis of resting‐state fMRI data, we provide evidence that Openness to Experience—a normally distributed personality trait reflecting a tendency to engage in imaginative, creative, and abstract cognitive processes—underlies efficiency of information processing within the DN. Across two studies, Openness predicted the global efficiency of a functional network comprised of DN nodes and corresponding edges. In Study 2, Openness remained a robust predictor—even after controlling for intelligence, age, gender, and other personality variables—explaining 18% of the variance in DN functioning. These findings point to a biological basis of Openness to Experience, and suggest that normally distributed personality traits affect the intrinsic architecture of large‐scale brain systems. Hum Brain Mapp 37:773–779, 2016. © 2015 Wiley Periodicals, Inc.
Can High‐frequency Trading Strategies Constantly Beat the Market?
Authors: Manahov Viktor 
Published: November 2015

AbstractPolicymakers are still debating whether or not high‐frequency trading (HFT) is beneficial or harmful to financial markets. We develop four artificial stock markets populated with HFT scalpers and aggressive high‐frequency traders using Strongly Typed Genetic Programming trading algorithm. We simulate real‐life HFT by applying Strongly Typed Genetic Programming to real‐time millisecond data of Apple, Bank of America, Russell 1000 and Russell 2000 and observe that HFT scalpers front‐run the order flow generating persistent profits. We also use combinations of forecasting techniques as benchmarks to demonstrate that HFT scalping strategies anticipate the trading order flow and constantly beat the market. Copyright © 2015 John Wiley & Sons, Ltd.