bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nitrogen Photofixation over III‐Nitride Nanowires Assisted by Ruthenium Clusters of Low Atomicity
Authors: Li Lu , Wang Yichen , Vanka Srinivas , Mu Xiaoyue , Mi Zetian , Li Chao‐Jun 
Published: June 2017

AbstractIn many heterogeneous catalysts, the interaction of supported metal species with a matrix can alter the electronic and morphological properties of the metal and manipulate its catalytic properties. III‐nitride semiconductors have a unique ability to stabilize ultra‐small ruthenium (Ru) clusters (ca. 0.8 nm) at a high loading density up to 5 wt %. n‐Type III‐nitride nanowires decorated with Ru sub‐nanoclusters offer controlled surface charge properties and exhibit superior UV‐ and visible‐light photocatalytic activity for ammonia synthesis at ambient temperature. A metal/semiconductor interfacial Schottky junction with a 0.94 eV barrier height can greatly facilitate photogenerated electron transfer from III‐nitrides to Ru, rendering Ru an electron sink that promotes N≡N bond cleavage, and thereby achieving low‐temperature ammonia synthesis.
Copper‐Catalyzed Enantio‐, Diastereo‐, and Regioselective [2,3]‐Rearrangements of Iodonium Ylides
Authors: Xu Bin , Tambar Uttam K. 
Published: June 2017

AbstractThe first highly enantioselective, diastereoselective, and regioselective [2,3]‐rearrangement of iodonium ylides has been developed as a general solution to catalytic onium ylide rearrangements. In the presence of a chiral copper catalyst, substituted allylic iodides couple with α‐diazoesters to generate metal‐coordinated iodonium ylides, which undergo [2,3]‐rearrangements with high selectivities (up to >95:5 r.r., up to >95:5 d.r., and up to 97 % ee). The enantioenriched iodoester products can be converted stereospecifically into a variety of onium ylide rearrangement products, as well as compounds that are not accessible by classical onium ylide rearrangements.
Application of natural rubber latex as scaffold for osteoblast to guided bone regeneration
Authors: Borges Felipe Azevedo , de Barros Natan Roberto , Garms Bruna Cambraia , Miranda Matheus Carlos Romeiro , Gemeinder Jose Lucio Padua , Ribeiro‐Paes João Tadeu , Silva Rodrigo Ferreira , de Toledo Karina Alves , Herculano Rondinelli Donizetti 
Published: June 2017

ABSTRACTNatural rubber latex (NRL) from Hevea brasiliensis is a colloidal system composed of cis‐1,4‐polyisoprene. Its applications have grown due its angiogenic and wound healing activity. NRL has been used in guided bone regeneration as barrier, enhancing bone formation. However, there has been no study reported so far which shows its in vitro biocompatibility with osteoblasts. Thus, the aim of this work was to apply thermally induced phase separation under several temperatures to induce porosity in NRL; and test its mechanical properties, cytotoxicity, cell adhesion, and mineralization with MC3T3‐E1. Only biomembranes submitted at −20 and −10 °C presented porosity. Fourier transform infrared spectroscopy showed no change in cis‐1,4‐isoprene spectra. Biomembranes were elastic (Young's modulus < 1 MPa). According to ISO10993–5, NRL showed no cytotoxicity. Cells adhered on the NRL and produced mineral matrix as analyzed by scanning electron microscopy–energy‐dispersive spectrometry, von kossa, and Fourier transform infrared spectroscopy. Cells on NRL presented higher alkaline phosphatase activity, however, mineralization showed no difference by alizarin red S dye extraction. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45321.
Preparation and electrodeformation of silicone dielectric elastomers containing poly(propylene glycol diacetate) with different molecular weights
Authors: Wang Gen Lin , Zhang Yi Yang , Zhang Jie , Ding Ke Hong , Wang Zhi Feng , Zhang Ming 
Published: June 2017

ABSTRACTIn this study, poly(propylene glycol diacetate)s (PPGDAs) with different molecular weights were obtained by the esterification reaction of poly(propylene glycol) and acetic anhydride. We effectively reduced the residual moisture and hydrophilicity of PPGDA. Then, poly(dimethyl siloxane) (PDMS) was modified by the addition of only 5 wt % PPGDA, which possessed a high dielectric constant (k) and a large actuated strain at a low electric field. PPGDA was used to enhance the molecular polarity because of the more polar oxygen atoms and the greater number of ester groups. The great increase in k and the low elastic modulus of the PPGDA–PDMS composites lead to a great increase in the electromechanical sensitivity. When the molecular weight of PPGDA was about 4000, the PPGDA–PDMS composites had the largest actuated strain. As a result, compared to the pure silicone elastomer (8.94%), it exhibited a greater strain of 17.31% at a low electric field of 10.5 V/μm (an increase of ca. 1.94 times). © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45329.
Thermal and mechanical properties of polyamide 12/graphene nanoplatelets nanocomposites and parts fabricated by fused deposition modeling
Authors: Zhu Dingchun , Ren Yuanyuan , Liao Guangxin , Jiang Shenglong , Liu Fenghua , Guo Jianjun , Xu Gaojie 
Published: June 2017

ABSTRACTThe printable polyamide 12 (PA12) nanocomposite filaments with 6 wt % graphene nanoplatelets (GNPs) for fused deposition modeling (FDM) were prepared by melting compounding and smoothly printed via a commercial FDM three‐dimensional (3D) printer. The thermal conductivity (λ) and elastic modulus (E) of 3D printed PA12/GNPs parts along to the printing direction had an increase by 51.4% and 7% than that of compression molded parts, which is due to the GNPs preferentially aligning along to the printing direction. Along with these improved properties, ultimate tensile strength of 3D printed PA12/GNPs parts was well maintained. These results indicate that FDM is a new way to achieve PA12/GNPs parts with enhanced λ over compression moulding, which could contribute to realize efficient and flexible heat management for a wide range of applications. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45332.
Acrolein Scavenger Hydralazine Prevents Streptozotocin‐Induced Painful Diabetic Neuropathy and Spinal Neuroinflammation in Rats
Authors: Yao Lu , Wu Yun‐Tao , Tian Guo‐Xiang , Xia Chang‐Quan , Zhang Feng , Zhang Wei 
Published: June 2017

ABSTRACTDiabetes‐induced neuropathic pain (DNP) substantially influences people's life qualities. Hyperglycemia‐induced excess free radicals have been considered as the most critical mechanisms underlying DNP. As an unsaturated aldehyde and a reactive product of lipid peroxidation, acrolein plays critical roles in diabetic nephropathy and inflammatory pain. We sought to determine whether acrolein is involved in DNP in this study. Diabetes was induced by a single intraperitoneal (i.p.) injection of 60 mg/kg streptozotocin (STZ). An acrolein scavenger hydralazine (5 mg/kg) was administered through a daily injection for 4 weeks, starting immediately within 30 min after STZ injection. Western blot showed that hydralazine could effectively inhibit STZ‐induced upregulation of acrolein in the spinal dorsal horn on day 7–28 after STZ injection. Behavioral tests showed that STZ injection induced significant mechanical allodynia and thermal hyperalgesia, which could be alleviated by hydralazine. Immunofluorescent histochemistry and Western blot showed that STZ induced significant microglial activation. ELISA data indicated upregulation of inflammatory cytokines IL‐1β and TNF‐α expression in the spinal dorsal horn. Furthermore, hydralazine effectively attenuated microglial activation and expression of inflammatory mediators. Our data indicate that acrolein might be involved in the development of neuroinflammation and behavioral consequences of DNP. Anat Rec, 2017. © 2017 Wiley Periodicals, Inc. Anat Rec, 300:1858–1864, 2017. © 2017 Wiley Periodicals, Inc.
Bone tissue bioprinting for craniofacial reconstruction
Authors: Datta Pallab , Ozbolat Veli , Ayan Bugra , Dhawan Aman , Ozbolat Ibrahim T. 
Published: June 2017

ABSTRACTCraniofacial (CF) tissue is an architecturally complex tissue consisting of both bone and soft tissues with significant patient specific variations. Conditions of congenital abnormalities, tumor resection surgeries, and traumatic injuries of the CF skeleton can result in major deficits of bone tissue. Despite advances in surgical reconstruction techniques, management of CF osseous deficits remains a challenge. Due its inherent versatility, bioprinting offers a promising solution to address these issues. In this review, we present and analyze the current state of bioprinting of bone tissue and highlight how these techniques may be adapted to serve regenerative therapies for CF applications. Biotechnol. Bioeng. 2017;114: 2424–2431. © 2017 Wiley Periodicals, Inc.
Rerouting of carbon flux in a glycogen mutant of cyanobacteria assessed via isotopically non‐stationary 13C metabolic flux analysis
Authors: Hendry John I. , Prasannan Charulata , Ma Fangfang , Möllers K. Benedikt , Jaiswal Damini , Digmurti Madhuri , Allen Doug K. , Frigaard Niels‐Ulrik , Dasgupta Santanu , Wangikar Pramod P. 
Published: June 2017

ABSTRACTCyanobacteria, which constitute a quantitatively dominant phylum, have attracted attention in biofuel applications due to favorable physiological characteristics, high photosynthetic efficiency and amenability to genetic manipulations. However, quantitative aspects of cyanobacterial metabolism have received limited attention. In the present study, we have performed isotopically non‐stationary 13C metabolic flux analysis (INST‐13C‐MFA) to analyze rerouting of carbon in a glycogen synthase deficient mutant strain (glgA‐I glgA‐II) of the model cyanobacterium Synechococcus sp. PCC 7002. During balanced photoautotrophic growth, 10–20% of the fixed carbon is stored in the form of glycogen via a pathway that is conserved across the cyanobacterial phylum. Our results show that deletion of glycogen synthase gene orchestrates cascading effects on carbon distribution in various parts of the metabolic network. Carbon that was originally destined to be incorporated into glycogen gets partially diverted toward alternate storage molecules such as glucosylglycerol and sucrose. The rest is partitioned within the metabolic network, primarily via glycolysis and tricarboxylic acid cycle. A lowered flux toward carbohydrate synthesis and an altered distribution at the glucose‐1‐phosphate node indicate flexibility in the network. Further, reversibility of glycogen biosynthesis reactions points toward the presence of futile cycles. Similar redistribution of carbon was also predicted by Flux Balance Analysis. The results are significant to metabolic engineering efforts with cyanobacteria where fixed carbon needs to be re‐routed to products of interest. Biotechnol. Bioeng. 2017;114: 2298–2308. © 2017 Wiley Periodicals, Inc.
Feature selective temporal prediction of Alzheimer's disease progression using hippocampus surface morphometry
Authors: Tsao Sinchai , Gajawelli Niharika , Zhou Jiayu , Shi Jie , Ye Jieping , Wang Yalin , Leporé Natasha 
Published: June 2017

AbstractIntroductionPrediction of Alzheimer's disease (AD) progression based on baseline measures allows us to understand disease progression and has implications in decisions concerning treatment strategy. To this end, we combine a predictive multi‐task machine learning method (cFSGL) with a novel MR‐based multivariate morphometric surface map of the hippocampus (mTBM) to predict future cognitive scores of patients.MethodsPrevious work has shown that a multi‐task learning framework that performs prediction of all future time points simultaneously (cFSGL) can be used to encode both sparsity as well as temporal smoothness. The authors showed that this method is able to predict cognitive outcomes of ADNI subjects using FreeSurfer‐based baseline MRI features, MMSE score demographic information and ApoE status. Whilst volumetric information may hold generalized information on brain status, we hypothesized that hippocampus specific information may be more useful in predictive modeling of AD. To this end, we applied a multivariate tensor‐based parametric surface analysis method (mTBM) to extract features from the hippocampal surfaces.ResultsWe combined mTBM features with traditional surface features such as middle axis distance, the Jacobian determinant as well as 2 of the Jacobian principal eigenvalues to yield 7 normalized hippocampal surface maps of 300 points each. By combining these 7 × 300 = 2100 features together with the previous ~350 features, we illustrate how this type of sparsifying method can be applied to an entire surface map of the hippocampus that yields a feature space that is 2 orders of magnitude larger than what was previously attempted.ConclusionsBy combining the power of the cFSGL multi‐task machine learning framework with the addition of AD sensitive mTBM feature maps of the hippocampus surface, we are able to improve the predictive performance of ADAS cognitive scores 6, 12, 24, 36 and 48 months from baseline.
Validity and reliability of the Fatigue Severity Scale in Finnish multiple sclerosis patients
Authors: Rosti‐Otajärvi Eija , Hämäläinen Päivi , Wiksten Anna , Hakkarainen Tanja , Ruutiainen Juhani 
Published: June 2017

AbstractBackgroundFatigue is one of the most debilitating symptoms in multiple sclerosis (MS) considerably interfering with patients’ daily functioning. Both researchers and clinicians need psychometrically robust methods to evaluate fatigue in MS.ObjectivesThe objective of this study was (i) to evaluate the psychometric properties of the Finnish version of the Fatigue Severity Scale (FSS) and (ii) to describe the results among patients with MS.MethodsIn total, 553 patients with MS (mean age, 53.8 years; standard deviation [SD], 11.4; 79% women: mean patient‐defined disease severity, Expanded Disability Status Scale [EDSS] 4.0, SD, 2.5) completed the self‐administered questionnaires including the FSS. A standard procedure was used for the translation of the FSS.ResultsThe mean (SD) score for the FSS was 4.5 (1.7); in 65% of the patients, the score was ≥4.0. The data quality of the FSS was excellent, with 99.6% of computable scale scores. Floor and ceiling effects were minimal. The FSS showed high internal consistency (Cronbach's alpha, 0.95). Unidimensionality was supported based on confirmatory factor analysis with the comparative fit index being 0.94. The FSS showed moderate/high correlations with the perceived burden of the disease, quality of life and disease severity, whereas, age or gender did not have a significant effect on the FSS score.ConclusionsThe Finnish version of the FSS showed satisfactory reliability and validity and thus can be regarded as a feasible measure of self‐reported fatigue.
Selective Catalytic Performances of Noble Metal Nanoparticle@MOF Composites: The Concomitant Effect of Aperture Size and Structural Flexibility of MOF Matrices
Authors: Chen Luning , Zhan Wenwen , Fang Huihuang , Cao Zhenmin , Yuan Chaofan , Xie Zhaoxiong , Kuang Qin , Zheng Lansun 
Published: June 2017

AbstractNoble metal nanoparticles embedded in metal–organic frameworks (MOFs) are composite catalysts with enhanced or novel properties compared to the pristine counterparts. In recent years, to determine the role of MOFs during catalytic process, most studies have focussed on the confinement effect of MOFs, but ignored the structural flexibility of MOFs. In this study, we use two composite catalysts, Pt@ZIF‐8 [Zn(mIM)2, mIM=2‐methyl imidazole] with flexible structure and Pt@ZIF‐71 [Zn(DClIM)2, DClIM=4,5‐dichloroimidazole] with rigid structure, and hydrogenation of cinnamaldehyde as model reaction, to show the confinement effect and the structure flexibility of MOF matrices on the catalytic performance of composite catalysts. Both catalysts showed high selectivity for cinnamic alcohol with the confinement effect of the aperture. But, compared to Pt@ZIF‐71, Pt@ZIF‐8 exhibited higher conversion but lower selectivity owing to the flexible structure. The above results remind us that we will have to consider both the aperture size of MOFs and structure flexibility to select the proper MOF matrices for the composite materials to achieve the optimized performance.
Fatty acid methyl ester heterogeneous self‐metathesis in hydrophobic green solvent: Mass transfer limitations, catalyst recyclability, and stability
Authors: Hasib‐ur‐Rahman Muhammad , Hamoudi Safia , Belkacemi Khaled 
Published: June 2017

AbstractThe role of room‐temperature ionic liquids (RTILs), [bmim][PF6] and [bmim][Tf2N], as reaction media regarding the catalytic activity and stability of methyltrioxorhenium (MTO) supported on ZnCl2‐modified mesoporous Al2O3 has been studied for self‐metathesis of a functionalized olefin, methyl oleate. The humidity influence on the catalytic activity was probed. The catalyst recycling ability and the kinetics of the metathesis reaction using these RTILs were also investigated. It was found that the MTO‐based catalyst was efficient in viscous hydrophobic RTIL solvents. However, their high viscosity was found to increase the mass transfer limitations thus somewhat impacting the reaction kinetics. Nevertheless, better catalyst stability was reached allowing its possible recycling when used in RTIL media.
Do red prices also work online?: An extension of Puccinelli et al. (2013)
Authors: Van Droogenbroeck Ellen , Van Hove Leo , Cordemans Steven 
Published: June 2017

AbstractIn a recent article, Puccinelli et al. examine the effect of the color in which prices appear in print flyers on consumers' perceived savings. Puccinelli et al. find that the effect is moderated by gender: unlike female consumers, men think they are being offered a better deal when prices are presented in red than when they are presented in black. The advertisements with prices in red also put men in a more positive state. This note replicates Puccinelli et al.'s main experiment in a different context (online vs. print) and in a different cultural setting (Belgium vs. the USA). In line with Puccinelli et al., we find that men perceive the online store with red prices as offering better value. But, intriguingly, it does not appear to make men feel more positively. One possible explanation is that red prices work differently online.
An Efficient and Versatile Lanthanum Heteroscorpionate Catalyst for Carbon Dioxide Fixation into Cyclic Carbonates
Authors: Martínez Javier , Fernández‐Baeza Juan , Sánchez‐Barba Luis F. , Castro‐Osma José A. , Lara‐Sánchez Agustín , Otero Antonio 
Published: June 2017

AbstractA new lanthanum heteroscorpionate complex has shown exceptional catalytic activity for the synthesis of cyclic carbonates from epoxides and carbon dioxide. This catalyst system also promotes the reaction of bio‐based epoxides to give an important class of bis(cyclic carbonates) that can be further used for the production of bio‐derived non‐isocyanate polyurethanes. The catalytic process requires low catalyst loading and mild reaction conditions for the synthesis of a wide range of cyclic carbonates.
A new electro‐static micro‐generator for energy harvesting from diaphragm muscle
Authors: Daneshvar Seyed Hossein , Maymandi‐Nejad Mohammad 
Published: June 2017

SummaryIn this paper, we propose a new energy scavenging system for powering bio‐implantable devices. Different available energy sources and micro‐generators are examined. The operation of electrostatic generators will be examined in detail, and their design issues are discussed. The proposed generator is analyzed, and a closed form formula is developed for the capacitor voltages. Also, an equation is obtained for the output power for the proposed circuit. It will be shown that the diaphragm muscle in conjunction with the electrostatic micro‐generator can be used to extract energy from human body. The diaphragm muscle has a continuous movement with a relatively fixed frequency. There is enough space around this muscle to place the micro‐generator. Using the proposed system, it will be shown that it is possible to produce 230 mW power in a 125 mm3 volume from the diaphragm muscle. Copyright © 2017 John Wiley & Sons, Ltd.
Non‐targeted acquisition strategy for screening doping compounds based on GC‐EI‐hybrid quadrupole‐Orbitrap mass spectrometry: A focus on exogenous anabolic steroids
Authors: de Albuquerque Cavalcanti Gustavo , Rodrigues Lucas Martins , dos Santos Leonardo , Zheng Xin , Gujar Amit , Cole Jason , Padilha Monica Costa , de Aquino Neto Francisco Radler 
Published: June 2017

This is a first look at a non‐targeted screening method based on Orbitrap gas chromatography–mass spectrometry (GC–MS) technology for a large number of banned compounds in sports found in urine, including exogenous anabolic steroids, β‐agonists, narcotics, stimulants, hormone modulators, and diuretics. A simple sample preparation was processed in four steps: an enzymatic hydrolysis, liquid–liquid extraction, evaporation, and trimethylsilylation. All compounds were able to meet the World Anti‐Doping Agency's sensitivity criteria with mass accuracies less than 1 ppm and with sufficient points across the peak by running the Orbitrap GC–MS in full‐scan mode. In addition, we discuss our initial findings of using a full‐scan selected ion monitoring‐tandem mass spectrometry (SIM‐MS/MS) approach as a way to obtain lower detection limits and reach desirable selectivity for some exogenous anabolic steroids.
Balanced Bcl‐3 expression in murine CD4+ T cells is required for generation of encephalitogenic Th17 cells
Authors: Mufazalov Ilgiz A. , Kuschmann Janina , Andruszewski David , Masri Joumana , Gabriel Laureen A. , Adams Petra , Reissig Sonja , Hövelmeyer Nadine , Waisman Ari 
Published: June 2017

The function of NF‐κB family members is controlled by multiple mechanisms including the transcriptional regulator Bcl‐3, an atypical member of the IκB family. By using a murine model of conditional Bcl‐3 overexpression specifically in T cells, we observed impairment in the development of Th2, Th1, and Th17 cells. High expression of Bcl‐3 promoted CD4+ T‐cell survival, but at the same time suppressed proliferation in response to TCR stimulation, resulting in reduced CD4+ T‐cell expansion. As a consequence, T‐cell‐specific overexpression of Bcl‐3 led to reduced inflammation in the small intestine of mice applied with anti‐CD3 in a model of gut inflammation. Moreover, impaired Th17‐cell development resulted in the resistance of Bcl‐3 overexpressing mice to EAE, a mouse model of multiple sclerosis. Thus, we concluded that fine‐tuning expression of Bcl‐3 is needed for proper CD4+ T‐cell development and is required to sustain Th17‐cell mediated pathology.