bluuebunny/crossref_metadata_2025_split huggingface dataset:
Діагностика та хірургічна корекція атипових проявів гастроезофагеальної рефлюксної хвороби
Authors: Veligotskiy M. M. , Grubnik V. V. , Komarchuk V. V. , Komarchuk Ye. V. , Paranyak M. R. , Grubnik V. V. 
Published: September 2017

У 10% пацієнтів при гастроезофагеальній рефлексній хворобі (ГЕРХ) відсутні типові прояви захворювання, а основні симптоми виявляють у дихальній, серцево–судинній системах, ЛОР–органах.
Мета. Покращення діагностичного алгоритму при виявленні позастравохідних проявів ГЕРХ; встановлення ефективності лапароскопічної фундоплікації у хворих за різних видів гастроезофагеального рефлюксу (ГЕР).
Матеріали і методи. З використанням опитувальників якості життя (ЯЖ) SF–36 та GERD–HRQL оцінювали віддалені результати консервативної терапії та хірургічного лікування пацієнтів за наявності респіраторних та ЛОР проявів ГЕРХ.
Результати. Більш суттєве покращення фізичного та психологічного компонентів ЯЖ відзначене у хворих, яким виконували лапароскопічну фундоплікацію. За опитувальником GERD–HRQL, ЯЖ хворих пысля хірургічного лікування покращилась через 6 міс – з (16,4 ± 5,3) до (6,2 ± 0,6) бала (р < 0,001), через 12 міс – до (6,4 ± 0,8) бала (р < 0,001); після консервативної терапії через 6 міс – з (15,9 ± 6,6) до (9,2 ± 1,9) бала (р < 0,001), через 12 міс – до (11,4 ± 1,5) бала (р < 0,05).
Висновки. Лапароскопічна фундоплікація порівняно з консервативною терапією більш ефективний метод лікування пацієнтів за наявності позастравохідних проявів ГЕРХ.
The interperiosteodural concept applied to the jugular foramen and its compartmentalization
Authors: Bernard Florian , Zemmoura Ilyess , Cottier Jean Philippe , Fournier Henri-Dominique , Terrier Louis-Marie , Velut Stéphane 
Published: September 2017

OBJECTIVEThe dura mater is made of 2 layers: the endosteal layer (outer layer), which is firmly attached to the bone, and the meningeal layer (inner layer), which directly covers the brain and spinal cord. These 2 dural layers join together in most parts of the skull base and cranial convexity, and separate into the orbital and perisellar compartments or into the spinal epidural space to form the extradural neural axis compartment (EDNAC). The EDNAC contains fat and/or venous blood. The aim of this dissection study was to anatomically verify the concept of the EDNAC by focusing on the dural layers surrounding the jugular foramen area.METHODSThe authors injected 10 cadaveric heads (20 jugular foramina) with colored latex and fixed them in formalin. The brainstem and cerebellum of 7 specimens were cautiously removed to allow a superior approach to the jugular foramen. Special attention was paid to the meningeal architecture of the jugular foramen, the petrosal inferior sinus and its venous confluence with the sigmoid sinus, and the glossopharyngeal, vagus, and accessory nerves. The 3 remaining heads were bleached with a 20% hydrogen peroxide solution. This procedure produced softening of the bone without modifying the fixed soft tissues, thus permitting coronal and axial dissections.RESULTSThe EDNAC of the jugular foramen was limited by the endosteal and meningeal layers and contained venous blood. These 2 dural layers joined together at the level of the petrous and occipital bones and separated at the inferior petrosal sinus and the sigmoid sinus, and around the lower cranial nerves, to form the EDNAC. Study of the dural sheaths allowed the authors to describe an original compartmentalization of the jugular foramen in 3 parts: 2 neural compartments—glossopharyngeal and vagal—and the interperiosteodural compartment.CONCLUSIONSIn this dissection study, the existence of the EDNAC concept in the jugular foramen was demonstrated, leading to the proposal of a novel 3-part compartmentalization, challenging the classical 2-part compartmentalization, of the jugular foramen.
Stereotactic radiosurgery for Spetzler-Martin Grade IV and V arteriovenous malformations: an international multicenter study
Authors: Patibandla Mohana Rao , Ding Dale , Kano Hideyuki , Xu Zhiyuan , Lee John Y. K. , Mathieu David , Whitesell Jamie , Pierce John T. , Huang Paul P. , Kondziolka Douglas , Feliciano Caleb , Rodriguez-Mercado Rafael , Almodovar Luis , Grills Inga S. , Silva Danilo , Abbassy Mahmoud , Missios Symeon , Barnett Gene H. , Lunsford L. Dade , Sheehan Jason P. 
Published: September 2017

OBJECTIVEDue to the complexity of Spetzler-Martin (SM) Grade IV–V arteriovenous malformations (AVMs), the management of these lesions remains controversial. The aims of this multicenter, retrospective cohort study were to evaluate the outcomes after single-session stereotactic radiosurgery (SRS) for SM Grade IV–V AVMs and determine predictive factors.METHODSThe authors retrospectively pooled data from 233 patients (mean age 33 years) with SM Grade IV (94.4%) or V AVMs (5.6%) treated with single-session SRS at 8 participating centers in the International Gamma Knife Research Foundation. Pre-SRS embolization was performed in 71 AVMs (30.5%). The mean nidus volume, SRS margin dose, and follow-up duration were 9.7 cm3, 17.3 Gy, and 84.5 months, respectively. Statistical analyses were performed to identify factors associated with post-SRS outcomes.RESULTSAt a mean follow-up interval of 84.5 months, favorable outcome was defined as AVM obliteration, no post-SRS hemorrhage, and no permanently symptomatic radiation-induced changes (RIC) and was achieved in 26.2% of patients. The actuarial obliteration rates at 3, 7, 10, and 12 years were 15%, 34%, 37%, and 42%, respectively. The annual post-SRS hemorrhage rate was 3.0%. Symptomatic and permanent RIC occurred in 10.7% and 4% of the patients, respectively. Only larger AVM diameter (p = 0.04) was found to be an independent predictor of unfavorable outcome in the multivariate logistic regression analysis. The rate of favorable outcome was significantly lower for unruptured SM Grade IV–V AVMs compared with ruptured ones (p = 0.042). Prior embolization was a negative independent predictor of AVM obliteration (p = 0.024) and radiologically evident RIC (p = 0.05) in the respective multivariate analyses.CONCLUSIONSIn this multi-institutional study, single-session SRS had limited efficacy in the management of SM Grade IV–V AVMs. Favorable outcome was only achieved in a minority of unruptured SM Grade IV–V AVMs, which supports less frequent utilization of SRS for the management of these lesions. A volume-staged SRS approach for large AVMs represents an alternative approach for high-grade AVMs, but it requires further investigation.
Timing and risks of chemoprophylaxis after spinal surgery: a single-center experience with 6869 consecutive patients
Authors: Dhillon Ekamjeet S. , Khanna Ryan , Cloney Michael , Roberts Helena , Cybulski George R. , Koski Tyler R. , Smith Zachary A. , Dahdaleh Nader S. 
Published: September 2017

OBJECTIVEVenous thromboembolism (VTE) after spinal surgery is a major cause of morbidity, but chemoprophylactic anticoagulation can prevent it. However, there is variability in the timing and use of chemoprophylactic anticoagulation after spine surgery, particularly given surgeons’ concerns for spinal epidural hematomas. The goal of this study was to provide insight into the safety, efficacy, and timing of anticoagulation therapy after spinal surgery.METHODSThe authors retrospectively examined records from 6869 consecutive spinal surgeries performed in their departments at Northwestern University. Data on patient demographics, surgery, hospital course, timing of chemoprophylaxis, and complications, including deep venous thrombosis (DVT), pulmonary embolism (PE), and spinal epidural hematomas requiring evacuation, were collected. Data from the patients who received chemoprophylaxis (n = 1904) were compared with those of patients who did not (n = 4965). The timing of chemoprophylaxis, the rate of VTEs, and the incidence of spinal epidural hematomas were analyzed.RESULTSThe chemoprophylaxis group had more risk factors, including greater age (59.70 vs 51.86 years, respectively; p < 0.001), longer surgery (278.59 vs 145.66 minutes, respectively; p < 0.001), higher estimated blood loss (995 vs 448 ml, respectively; p < 0.001), more comorbid diagnoses (2.69 vs 1.89, respectively; p < 0.001), history of VTE (5.8% vs 2.1%, respectively; p < 0.001), and a higher number were undergoing fusion surgery (46.1% vs 24.7%, respectively; p < 0.001). The prevalence of VTE was higher in the chemoprophylaxis group (3.62% vs 2.03%, respectively; p < 0.001). The median time to VTE occurrence was shorter in the nonchemoprophylaxis group (3.6 vs 6.8 days, respectively; p = 0.0003, log-rank test; hazard ratio 0.685 [0.505–0.926]), and the peak prevalence of VTE occurred in the first 3 postoperative days in the nonchemoprophylaxis group. The average time of initiation of chemoprophylaxis was 1.46 days after surgery. The rates of epidural hematoma were 0.20% (n = 4) in the chemoprophylaxis group and 0.18% (n = 9) in the nonchemoprophylaxis group (p = 0.622).CONCLUSIONSThe risks of spinal epidural hematoma among patients who receive chemoprophylaxis and those who do not are low and equivalent. Administering anticoagulation therapy from 1 day before to 3 days after surgery is safe for patients at high risk for VTE.
Utility and costs of radiologist interpretation of perioperative imaging in patients with traumatic single-level thoracolumbar fractures
Authors: Weber Michael H. , Sivakumaran Lojan , Fortin Maryse , Teles Alisson R. , Golan Jeff D. , Santaguida Carlo , Jarzem Peter , Pauyo Thierry 
Published: September 2017

OBJECTIVEThe cost of spine management is rising. As diagnostic imaging accounts for approximately 10% of total patient care spending, there is interest in determining if economies could be made with regard to the routine consultation of radiology for image interpretation. In the context of spine trauma, both the spine surgeon and the radiologist interpret perioperative imaging. Authors of the present study investigated the impact of radiologist interpretation of perioperative imaging from patients with traumatic single-level thoracolumbar fractures given that spine surgeons are expected to be comfortable interpreting pathologies of the musculoskeletal system.METHODSThe authors conducted a retrospective review of all patients presenting with a single-level thoracolumbar fracture treated at the McGill University Health Centre in the period from January 2003 to December 2010. The time between image capture and radiologist interpretation as well as the number of extraskeletal and/or incidental findings was extracted from the radiology reports on all perioperative images including radiographic, fluoroscopic, and CT images. The cost of interpretation was obtained from the provincial health insurance entity of Quebec.RESULTSEighty-two patients met the study inclusion criteria. Radiologists took a median of 1 day (IQR 0–5.5 days) to interpret preoperative radiographs. Intraoperative fluoroscopic images and postoperative radiographs were read by the radiologist a median of 19 days (IQR 4–56.75 days) and 34 days (IQR 1–137.5 days) after capture, respectively (p < 0.05). Preoperative radiologist dictations reported extraskeletal and/or incidental findings for 8.1% of radiographs; there were no intraoperative or postoperative extraskeletal findings beyond those previously reported on the preoperative radiographs. Radiologists took a median of 1 day (IQR 0–1 day) to read both preoperative and postoperative CT scans; extraskeletal and/or incidental findings were present in 46.2% of preoperative reports and 4.5% of postoperative reports. There were no intraoperative or postoperative radiological findings that provoked reoperation. A total of 66 intraoperative fluoroscopy images and 225 postoperative radiographs were read for a cost of $1399.20 and $1867.50 (Canadian dollars), respectively, for radiologist interpretation. This cost amounted to 40.3% of all perioperative image interpretation spending.CONCLUSIONSIn the management of single-level thoracolumbar fractures, radiologists add information to the diagnostic picture when interpreting preoperative radiographs and perioperative CT scans; however, the interpretation of intraoperative fluoroscopic images and postoperative radiographs comes with significant delay, does not add additional information, and represents an area of potential cost and professional-resource reduction.
Adaptation, Access to Resources and Mobility: From Contemporary Pastoral Systems to Ancient Societies
Authors: Salpeteur M. , Madella M. , Patel H.R. , Reyes-García V. 
Published: September 2017

Abstract
Building on the literature on adaptation and on examples from contemporary pastoralists in Gujarat, we explore dynamics of pastoral systems and, more precisely, their adaptive strategies. We specifically focus on resource accessibility and mobility and how those two issues relate with the broader institutional settings in which pastoral production is embedded. We then apply this conceptual framework to an archaeological site also found in Gujarat, Bagasra, in order to explore probable dynamics of the ancient pastoral system in relation to resources accessibility and mobility. Dealing with archaeological past is always difficult given the limited availability of data. We argue that the conceptual approach proposed here allow us to draw some hypotheses about adaptation strategies, for which it appears a relevant way to further explore the dynamics of ancient pastoral systems.
Allotetraploid cryptic species in Asplenium normale in the Japanese Archipelago, detected by chemotaxonomic and multi‐locus genotype approaches
Authors: Fujiwara Tao , Uehara Ayumi , Iwashina Tsukasa , Matsumoto Sadamu , Chang Yi‐Han , Chao Yi‐Shan , Watano Yasuyuki 
Published: September 2017

PREMISE OF THE STUDY:Delimitation of cryptic species provides an understanding of biodiversity and opportunities to elucidate speciation processes. Extensive flavonoid variation has been reported in the tetraploid cytotype of the fern, Asplenium normale, although related species have no intraspecific variations in flavonoid composition. We hypothesized that Japanese A. normale still harbors multiple cryptic species with different flavonoid compositions, and tested this hypothesis using chemotaxonomic and multilocus genotyping approaches.METHODS:We determined the multilocus genotypes (MLGs) of 230 samples from 37 populations for one chloroplast DNA region and three nuclear genes. MLGs were used to delimit reproductively isolated lineages by population‐genetic approaches. We also tested the correspondence between genetically recognized groups and flavonoid compositions. To identify the origins of putative cryptic species, we conducted phylogenetic analysis of the DNA markers used in genotyping.KEY RESULTS:The genetic clusters and flavonoid compositions showed clear correspondence. We recognized three putative cryptic species in tetraploid Asplenium normale in Japan. Phylogenetic analyses revealed that cryptic species I and III originated from allopolyploidization between a diploid A. normale and an unknown diploid of A. boreale, and cryptic species II originated from allopolyploidization between a diploid A. normale and A. oligophlebium.CONCLUSIONS:Our study demonstrated that intraspecific variation of secondary metabolites can be a good indicator of cryptic species in ferns. The presence of the two cryptic species having the same progenitor diploid pair suggests that speciation between allopolyploid lineages of independent origin may be more common than previously considered.
Space Weathering of Super-Earths: Model Simulations of Exospheric Sodium Escape from 61 Virgo b
Authors: Yoneda M. , Berdyugina S. , Kuhn J. 
Published: September 2017

Abstract
Rocky exoplanets are expected to be eroded by space weather in a similar way as in the solar system. In particular, Mercury is one of the dramatically eroded planets whose material continuously escapes into its exosphere and further into space. This escape is well traced by sodium atoms scattering sunlight. Due to solar wind impact, micrometeorite impacts, photo-stimulated desorption and thermal desorption, sodium atoms are released from surface regolith. Some of these released sodium atoms are escaping from Mercury’s gravitational-sphere. They are dragged anti-Sun-ward and form a tail structure. We expect similar phenomena on exoplanets. The hot super-Earth 61 Vir b orbiting a G3V star at only 0.05 au may show a similar structure. Because of its small separation from the star, the sodium release mechanisms may be working more efficiently on hot super-Earths than on Mercury, although the strong gravitational force of Earth-sized or even more massive planets may be keeping sodium atoms from escaping from the planet. Here, we performed model simulations for Mercury (to verify our model) and 61 Vir b as a representative super-Earth. We have found that sodium atoms can escape from this exoplanet due to stellar wind sputtering and micrometeorite impacts, to form a sodium tail. However, in contrast to Mercury, the tail on this hot super-Earth is strongly aligned with the anti-starward direction because of higher light pressure. Our model suggests that 61 Vir b seems to have an exo-base atmosphere like that of Mercury.
A Search for Additional Bodies in the GJ 1132 Planetary System from 21 Ground-based Transits and a 100-hr Spitzer Campaign
Authors: Dittmann Jason A. , Irwin Jonathan M. , Charbonneau David , Berta-Thompson Zachory K. , Newton Elisabeth R. 
Published: September 2017

Abstract
We present the results of a search for additional bodies in the GJ 1132 system through two methods: photometric transits and transit timing variations of GJ 1132b. We collected 21 transit observations of GJ 1132b with the MEarth-South array. We obtained 100 near-continuous hours of observations with the Spitzer Space Telescope, including two transits of GJ 1132b and spanning 60% of the orbital phase of the maximum (6.9-day) period at which bodies coplanar with GJ 1132b would transit. We exclude transits of additional Mars-sized bodies, such as a second planet or a moon, with a confidence of 99.7%. We find that the planet-to-star radius ratio inferred from the MEarth and Spitzer light curves are discrepant at the

level, which we ascribe to the effects of starspots and faculae. When we combine the mass estimate of the star (obtained from its parallax and apparent K

s
band magnitude) with the stellar density inferred from our high-cadence Spitzer light curve (assuming zero eccentricity), we measure the stellar radius of GJ 1132 to be

, and we refine the radius measurement of GJ 1132b to

. Combined with HARPS RV measurements, we determine the density of GJ 1132b to be 6.2 ± 2.0 g cm−3. We refine the ephemeris of the system (improving the period determination by an order of magnitude) and find no evidence for transit timing variations, which would be expected if there was a second planet near an orbital resonance with GJ 1132b.
Kink Waves in Non-isothermal Stratified Solar Waveguides: Effect of the External Magnetic Field
Authors: Lopin I. , Nagorny I. 
Published: September 2017

Abstract
We study the effect of an external magnetic field on the properties of kink waves, propagating along a thin non-isothermal stratified and diverging magnetic flux tube. A wave equation, governing the propagation of kink waves under the adopted model is derived. It is shown that the vertical gradient of temperature introduces a spatially local cut-off frequency ω

c
. The vertical distribution of the cut-off frequency is calculated for the reference VAL-C model of the solar atmosphere and for different values of a ratio of external to internal magnetic fields. The results show that the cut-off frequency is negative below the temperature minimum due to the negative temperature gradient. In the chromosphere the cut-off frequency at a given height is smaller for a stronger external magnetic field. For the appropriate range of a ratio B

e
/B

i
≈ 0–0.8, the cutoff lies in the range ω

c
≈ 0.003–0.010 s−1 (periods 600 < P

c
< 2000 s). The estimate of the cut-off frequency in the transition region is provided as well. In the propagating wave regime, the effective wave energy flux in the non-isothermal diverging flux tubes is the same as in the straight and homogeneous cylindrical waveguides. The obtained wave equation in the limit β = 0 is used to study the kink oscillations of non-isothermal coronal loops. It is found that the gradient of temperature along the coronal loops reduces the frequency ratio of the first overtone to the fundamental mode, i.e., ω
2/ω
1 < 2. This reduction grows for a larger ratio of temperature at the loop top to the temperature at the footpoints. Moreover, the effect of reduction is most pronounced for the steeper temperature profiles.
The Gaseous Phase as a Probe of the Astrophysical Solid Phase Chemistry
Authors: Abou Mrad Ninette , Duvernay Fabrice , Isnard Robin , Chiavassa Thierry , Danger Grégoire 
Published: September 2017

Abstract
In support of space missions and spectroscopic observations, laboratory experiments on ice analogs enable a better understanding of organic matter formation and evolution in astrophysical environments. Herein, we report the monitoring of the gaseous phase of processed astrophysical ice analogs to determine if the gaseous phase can elucidate the chemical mechanisms and dominant reaction pathways occurring in the solid ice subjected to vacuum ultra-violet (VUV) irradiation at low temperature and subsequently warmed. Simple (CH3OH), binary (H2O:CH3OH, CH3OH:NH3), and ternary ice analogs (H2O:CH3OH:NH3) were VUV-processed and warmed. The evolution of volatile organic compounds in the gaseous phase shows a direct link between their relative abundances in the gaseous phase, and the radical and thermal chemistries modifying the initial ice composition. The correlation between the gaseous and solid phases may play a crucial role in deciphering the organic composition of astrophysical objects. As an example, possible solid compositions of the comet Lovejoy are suggested using the abundances of organics in its comae.
AGILE Detection of a Candidate Gamma-Ray Precursor to the ICECUBE-160731 Neutrino Event
Authors: Lucarelli F. , Pittori C. , Verrecchia F. , Donnarumma I. , Tavani M. , Bulgarelli A. , Giuliani A. , Antonelli L. A. , Caraveo P. , Cattaneo P. W. , Colafrancesco S. , Longo F. , Mereghetti S. , Morselli A. , Pacciani L. , Piano G. , Pellizzoni A. , Pilia M. , Rappoldi A. , Trois A. , Vercellone S. 
Published: September 2017

Abstract
On 2016 July 31 the ICECUBE collaboration reported the detection of a high-energy starting event induced by an astrophysical neutrino. Here, we report on a search for a gamma-ray counterpart to the ICECUBE-160731 event, made with the AGILE satellite. No detection was found spanning the time interval of ±1 ks around the neutrino event time T
0 using the AGILE “burst search” system. Looking for a possible gamma-ray precursor in the results of the AGILE-GRID automatic Quick Look procedure over predefined 48-hr time bins, we found an excess above 100 MeV between 1 and 2 days before T
0, which is positionally consistent with the ICECUBE error circle, that has a post-trial significance of about

. A refined data analysis of this excess confirms, a posteriori, the automatic detection. The new AGILE transient source, named AGL J1418+0008, thus stands as a possible ICECUBE-160731 gamma-ray precursor. No other space missions nor ground observatories have reported any detection of transient emission consistent with the ICECUBE event. We show that Fermi-LAT had a low exposure for the ICECUBE region during the AGILE gamma-ray transient. Based on an extensive search for cataloged sources within the error regions of ICECUBE-160731 and AGL J1418+0008, we find a possible common counterpart showing some of the key features associated with the high-energy peaked BL Lac (HBL) class of blazars. Further investigations on the nature of this source using dedicated SWIFT ToO data are presented.