bluuebunny/crossref_metadata_2025_split huggingface dataset:
An empirical examination of the relationship between skills shortage and firm performance: The role of high-performance work systems
Authors: Malik Amina R. , Manroop Laxmikant , Patel Pankaj C. 
Published: May 2017

AbstractThere has been growing scholarly interest in the relationship between high-performance work systems and firm performance. Yet, limited research attention has been given to the impact of high-performance work systems on firm performance during skills shortages. In this study, we empirically examine the influence of high-performance work systems on firm performance in the midst of skills shortages. Results from a study of 211 US firms with 50 or more employees demonstrate that internal skills shortages are not related to firm profitability. Findings further show that the use of high-performance work systems is more detrimental to firm performance for firms when they face an internal skills shortage. These results are discussed and future research directions are offered.
Retorting conditions affect palatability and physical characteristics of canned cat food
Authors: Hagen-Plantinga Esther A. , Orlanes Denmark F. , Bosch Guido , Hendriks Wouter H. , van der Poel Antonius F. B. 
Published: May 2017

AbstractThe effects of different temperature and time conditions during retorting of canned cat food on physicochemical characteristics and palatability were examined. For this purpose, lacquer cans containing an unprocessed loaf-type commercial cat food were heated in a pressurised retorting system at three specified temperature–time profiles (113°C/232 min, 120°C/103 min and 127°C/60 min) to equal a similar lethality (F0 value = 30). Physicochemical properties (viscosity, texture, particle size, pH) were determined, and a 10 d three-bowl palatability test was performed with ten European shorthair cats. Retorting at 113°C/232 min resulted in differences in all the physical parameters examined (<viscosity, firmness, adhesiveness, and > particle size). Significant pH differences were observed (6·53, 6·63 and 6·66 for T113/232, 120 and 127°C, respectively). Preference ratios were 0·38, 0·31 and 0·31 for T113/232, 120 and 127°C, respectively (P = 0·067). It can be concluded that different retorting temperature–time profiles with equal F0 value significantly affect physical characteristics and tended to affect palatability of moist cat food.
Nutritional correlates of monetary diet cost in young, middle-aged and older Japanese women
Authors: Shiraki Keiko , Murakami Kentaro , Okubo Hitomi , Livingstone M. Barbara E. , Kobayashi Satomi , Suga Hitomi , Sasaki Satoshi ,   The Three-Generation Study of Women on Diets and Health Study Group
Published: May 2017

AbstractStudies in many Western countries have consistently shown that monetary diet cost is positively associated with diet quality, but this may not necessarily be the case in Japan. This cross-sectional study examined the nutritional correlates of monetary diet cost among 3963 young (all 18 years old), 3800 middle-aged (mean age 48 years) and 2211 older (mean age 74 years) Japanese women. Dietary intakes were assessed using a comprehensive self-administered diet history questionnaire for young and middle-aged women and a brief self-administered diet history questionnaire for older women. Monetary diet cost was estimated using retail food prices. Total vegetables, fish and shellfish, green and black tea, white rice, meat, fruit and alcoholic beverages contributed most (79–89 %) to inter-individual variation in monetary diet cost. Multiple regression analyses showed that monetary diet cost was negatively associated with carbohydrate intake, but positively with intakes of all other nutrients examined (including not only dietary fibre and key vitamins and minerals but also saturated fat and Na) in all generations. For food group intakes, irrespective of age, monetary diet cost was associated inversely with white rice and bread but positively with pulses, potatoes, fruit, total vegetables, fruit and vegetable juice, green and black tea, fish and shellfish, and meat. In conclusion, in all three generations of Japanese women and contrary to Western populations, monetary diet cost was positively associated with not only healthy dietary components (including fruits, vegetables, fish and shellfish, dietary fibre, and key vitamins and minerals), but also less healthy components (including saturated fat and Na).
Sexual shape dimorphism and selection pressure on males in fossil ostracodes
Authors: Yamaguchi Tatsuhiko , Honda Rie , Matsui Hiroki , Nishi Hiroshi 
Published: May 2017

AbstractSexual dimorphism is thought to have evolved via selection on both sexes. Ostracodes display sexual shape dimorphism in adult valves; however, no previous studies have addressed temporal changes on evolutionary timescales or examined the relationships between sexual shape dimorphism and selection pressure and between sexual shape dimorphism and juvenile shape. Temporal changes in sexually dimorphic traits result from responses of these traits to selection pressure. Using the Gaussian mixture model for the height/length ratio, a valve-shape parameter, we identified sexual differences in the valve shape ofKrithe dolichodeiras.l. from deep-sea sediments of the Paleocene (62.6–57.6 Ma) and estimated the proportion of females in the fossil populations at 11 time intervals. Because the proportion of females in a population is altered by the mortality rate of adult males, it is reflective of selection pressure on males. We attempted to correlate the height/length ratios between the sexes with the proportion of females, taking into consideration that the valve shape was not linked with the selection pressure on males. In time-series data of the height/length ratio, both sexes indicate no significant changes on evolutionary timescales, even though the sex ratio of the population changed from female skewed to male skewed during the late Paleocene. The sexual shape dimorphism was not driven by sexual selection. The static allometry between the height/length ratio and length indicates that the sexual shape dimorphism did not function for sexual display. The absence of change over time in the female allometric slope suggests that the evolution of valve shape was constrained by stasis.
Polymannuronic acid ameliorated obesity and inflammation associated with a high-fat and high-sucrose diet by modulating the gut microbiome in a murine model
Authors: Liu Fang , Wang Xiong , Shi Hongjie , Wang Yuming , Xue Changhu , Tang Qing-Juan 
Published: May 2017

AbstractPolymannuronic acid (PM), one of numerous alginates isolated from brown seaweeds, is known to possess antioxidant activities. In this study, we examined its potential role in reducing body weight gain and attenuating inflammation induced by a high-fat and high-sucrose diet (HFD) as well as its effect on modulating the gut microbiome in mice. A 30-d PM treatment significantly reduced the diet-induced body weight gain and blood TAG levels (P<0·05) and improved glucose tolerance in male C57BL/6J mice. PM decreased lipopolysaccharides in blood and ameliorated local inflammation in the colon and the epididymal adipose tissue. Compared with low-fat and low-sucrose diet (LFD), HFD significantly reduced the mean number of species-level operational taxonomic units (OTU) per sample as well as species richness (P<0·05) but did not appear to affect other microbial diversity indices. Moreover, compared with LFD, HFD altered the abundance of approximately 23 % of the OTU detected (log10 linear discriminant analysis (LDA) score>2·0). PM also had a profound impact on the microbial composition in the gut microbiome and resulted in a distinct microbiome structure. For example, PM significantly increased the abundance of a probiotic bacterium, Lactobacillus reuteri (log10 LDA score>2·0). Together, our results suggest that PM may exert its immunoregulatory effects by enhancing proliferation of several species with probiotic activities while repressing the abundance of the microbial taxa that harbor potential pathogens. Our findings should facilitate mechanistic studies on PM as a potential bioactive compound to alleviate obesity and the metabolic syndrome.
Organic zinc absorption by the intestine of broilersin vivo
Authors: Yu Yu , Lu Lin , Li Su-Fen , Zhang Li-Yang , Luo Xu-Gang 
Published: May 2017

AbstractIn Expt 1, a Zn-unsupplemented basal diet (control) and the basal diet supplemented with one of four different Zn sources, including ZnSO4, Zn-amino acid chelate with a weak chelation strength (Zn-AA W), Zn-protein chelate with a moderate chelation strength (Zn-Pro M) and Zn-protein chelate with a strong chelation strength (Zn-Pro S) were fed to broiler chickens from days 14 to 28. On day 28, Zn content in plasma from the hepatic portal vein increased (P<0·05) in the following order: control<ZnSO4<Zn-AA W<Zn-Pro M<Zn-Pro S. Meanwhile, metallothionein (MT) mRNA levels in the duodenum, jejunum and ileum were enhanced (P<0·05) by Zn addition regardless of Zn source. However, no differences among different Zn sources were observed. In Expt 2, ligated duodenal loops from Zn-deficient broilers (28-d old) were perfused with solutions containing 0–2·464 mmol Zn/l from the above-mentioned four Zn sources for up to 30 min. The uptake kinetics of Zn followed a saturable carrier-mediated process. The maximum absorption velocity values were in the following order: control<ZnSO4<Zn-AA W<Zn-Pro M<Zn-Pro S. Moreover, MT mRNA levels for Zn-Pro S (P<0·03), Zn-Pro M (P>0·05) and Zn-AA W(P<0·04) were higher than those for ZnSO4. These findings indicate that organic Zn absorption (especially Zn-Pro S) in intact living broilers was more effective than that of inorganic Zn; organic Zn absorption in the ligated duodenal segment was a saturable carrier-mediated process similar to that of ZnSO4. Moreover, except for MT, there might be other Zn transporters involved in Zn absorption that are affected by different Zn sources.
Application of nonlinear models to estimate the gain of one-dimensional free-electron lasers
Authors: Peter E. , Rizzato F. B. , Endler A. 
Published: May 2017

In the present work, we make use of simplified nonlinear models based on the compressibility factor (Peter et al., Phys. Plasmas, vol. 20 (12), 2013, 123104) to predict the gain of one-dimensional (1-D) free-electron lasers (FELs), considering space-charge and thermal effects. These models proved to be reasonable to estimate some aspects of 1-D FEL theory, such as the position $z$ of the onset of mixing, in the case of a initially cold electron beam, and the position $z$ of the breakdown of the laminar regime, in the case of an initially warm beam (Peter et al., Phys. Plasmas, vol. 21 (11), 2014, 113104). The results given by the models are compared to wave–particle simulations showing a reasonable agreement.
Contribution of seed banks across Europe towards the 2020 Global Strategy for Plant Conservation targets, assessed through the ENSCONET database
Authors: Rivière S. , Müller J. V. 
Published: May 2017

AbstractTo meet the international biodiversity targets of the 2011–2020 Global Strategy for Plant Conservation, it is important to assess the success of coordinated ex situ plant conservation initiatives such as the European Native Seed Conservation Network (ENSCONET), which operated during 2005–2009, and the ENSCONET Consortium, which was established in 2010. In particular, analysis of the ENSCONET database (ENSCOBASE) indicates that ex situ seed banks have been making significant progress towards meeting targets 8 (at least 75% of threatened plant species in ex situ collections, preferably in the country of origin, and at least 20% available for recovery and restoration programmes) and 9 (70% of the genetic diversity of crops, including their wild relatives and other socio-economically valuable plant species, conserved, while respecting, preserving and maintaining associated indigenous and local knowledge) for native European species. However, the infraspecific diversity of threatened species stored in ENSCONET seed banks needs to be increased to meet research and conservation objectives.
Early life history traits and geographical distribution ofParachaenichthys charcoti
Authors: La Mesa Mario , Riginella Emilio , Jones Christopher D. 
Published: May 2017

AbstractThe geographical distribution of the two species of the genusParachaenichthysis allopatric and restricted to the inner shelves of South Georgia–South Sandwich Islands (P. georgianus) and South Orkney Islands–South Shetland Islands (P. charcoti). To evaluate the consistency between the geographical patterns of adult distribution and early life history traits ofP. charcoti, sagittal otoliths were used to estimate growth rate and pelagic duration in larvae and juveniles of this species collected in the Bransfield Strait in winter and summer, respectively. Individual age was determined through microincrement counts, assuming they were daily increments. The Gompertz model was fitted to age–length estimates, providing a mean growth rate of 0.22 mm day-1estimated for 28–204-day-old individuals. Larval hatching was spread over a relatively wide period, lasting from July throughout September. The pelagic larval duration ofP. charcotiwas about six months based on ageing data of larvae and juveniles, as reported forP. georgianusfrom South Georgia. The strong dependence of larvae on the inshore habitat may hamper their dispersal at large spatial scale limiting the connectivity among distant populations, providing clues to interpret the present geographical distribution of the two species.
Tracing the origins of verlan in an early nineteenth century text?
Authors: BACH XAVIER 
Published: May 2017

ABSTRACTThis article examines early attestations of verlan and related backward slangs in French in the nineteenth century. Its main contribution is the edition and analysis of the only known text, a letter, written with features of verlan before the twentieth century. This largely predates other attested forms of verlan. The principles underlying this early form of verlan are shown to be different from contemporary verlan, as is much other early evidence, though all forms have the syllable as their basic unit. The letter is evidence that backward slangs can originate in the education system as much as in the underworld of thieves.
A linear algebraic approach to datalog evaluation
Authors: SATO TAISUKE 
Published: May 2017

AbstractWe propose a fundamentally new approach to Datalog evaluation. Given a linear Datalog program DB written usingNconstants and binary predicates, we first translate if-and-only-if completions of clauses in DB into a setEq(DB) of matrix equations with a non-linear operation, where relations inMDB, the least Herbrand model of DB, are encoded as adjacency matrices. We then translateEq(DB) into another, but purely linear matrix equationsẼq(DB). It is proved that the least solution ofẼq(DB) in the sense of matrix ordering is converted to the least solution ofEq(DB) and the latter givesMDBas a set of adjacency matrices. Hence, computing the least solution ofẼq(DB) is equivalent to computingMDBspecified by DB. For a class of tail recursive programs and for some other types of programs, our approach achievesO(N3) time complexity irrespective of the number of variables in a clause since only matrix operations costingO(N3) or less are used. We conducted two experiments that compute the least Herbrand models of linear Datalog programs. The first experiment computes transitive closure of artificial data and real network data taken from the Koblenz Network Collection. The second one compared the proposed approach with the state-of-the-art symbolic systems including two Prolog systems and two ASP systems, in terms of computation time for a transitive closure program and the same generation program. In the experiment, it is observed that our linear algebraic approach runs 101~ 104times faster than the symbolic systems when data is not sparse. Our approach is inspired by the emergence of big knowledge graphs and expected to contribute to the realization of rich and scalable logical inference for knowledge graphs.
αCheck: A mechanized metatheory model checker
Authors: CHENEY JAMES , MOMIGLIANO ALBERTO 
Published: May 2017

AbstractThe problem of mechanically formalizing and proving metatheoretic properties of programming language calculi, type systems, operational semantics, and related formal systems has received considerable attention recently. However, the dual problem of searching for errors in such formalizations has attracted comparatively little attention. In this article, we present αCheck, a bounded model checker for metatheoretic properties of formal systems specified using nominal logic. In contrast to the current state of the art for metatheory verification, our approach is fully automatic, does not require expertise in theorem proving on the part of the user, and produces counterexamples in the case that a flaw is detected. We present two implementations of this technique, one based onnegation-as-failureand one based onnegation elimination, along with experimental results showing that these techniques are fast enough to be used interactively to debug systems as they are developed.
Productivity in an arable and stockless organic cropping system may be enhanced by strategic recycling of biomass
Authors: Råberg Tora Matilda , Carlsson Georg , Jensen Erik Steen 
Published: May 2017

AbstractRecirculation of nitrogen (N) from crop residue and green-manure biomass resources may reduce the need to add new reactive N to maintain crop yield and quality. The aim of this study was to determine how different strategies for recycling residual and green-manure biomass influence yield and N concentration of the edible parts of food crops in a stockless organic cropping system. For this purpose, three biomass distribution treatments were investigated in a field experiment, based on a cropping system designed to produce both high-quality food crops and biomass resources from crop residues, cover crops and a green-manure ley. The three treatments, applied at the cropping system level, were: (1) incorporating the aboveground biomass resources in situ (IS); (2) harvesting, ensiling and redistributing the same biomass resources to the non-legume crops (biomass redistribution, BR); and (3) harvesting, ensiling and using the biomass resources as substrate for production of bio-methane via anaerobic digestion (AD) followed by distribution of the digestate as bio-fertilizer to the non-legume crops. The redistribution of ensiled (BR) and digested (AD) biomass did not increase the yield of the edible parts in winter rye (Secale cereal L.), white cabbage (Brassica oleracea L.) or red beet (Beta vulgaris L.) compared with leaving the biomass on the ground at harvest (IS). The BR treatment increased the yield of lentil intercropped with oat, compared with IS treatment in one of the two studied years. The total biomass yield of the cover crop following winter rye was significantly higher in the BR treatment than in IS in both years. The legume proportion in the green-manure ley was significantly higher in the AD and BR treatments as compared with IS in one of the experimental years. This study showed that strategic biomass redistribution has the potential to enhance biomass productivity while maintaining food crop yields, thereby enhancing whole system productivity. Biomass redistribution systems both with and without biogas digestion offer a new strategy for the development of multifunctional arable cropping systems that rely on internal nutrient cycling.
A unified approach to mortality modelling using state-space framework: characterisation, identification, estimation and forecasting
Authors: Fung Man Chung , Peters Gareth W. , Shevchenko Pavel V. 
Published: May 2017

AbstractThis paper explores and develops alternative statistical representations and estimation approaches for dynamic mortality models. The framework we adopt is to reinterpret popular mortality models such as the Lee–Carter class of models in a general state-space modelling methodology, which allows modelling, estimation and forecasting of mortality under a unified framework. We propose alternative model identification constraints which are more suited to statistical inference in filtering and parameter estimation. We then develop a class of Bayesian state-space models which incorporate a priori beliefs about the mortality model characteristics as well as for more flexible and appropriate assumptions relating to heteroscedasticity that present in observed mortality data. To study long-term mortality dynamics, we introduce stochastic volatility to the period effect. The estimation of the resulting stochastic volatility model of mortality is performed using a recent class of Monte Carlo procedure known as the class of particle Markov chain Monte Carlo methods. We illustrate the framework using Danish male mortality data, and show that incorporating heteroscedasticity and stochastic volatility markedly improves model fit despite an increase of model complexity. Forecasting properties of the enhanced models are examined with long-term and short-term calibration periods on the reconstruction of life tables.
MICU1 drives glycolysis and chemoresistance in ovarian cancer
Authors: Chakraborty Prabir K. , Mustafi Soumyajit Banerjee , Xiong Xunhao , Dwivedi Shailendra Kumar Dhar , Nesin Vasyl , Saha Sounik , Zhang Min , Dhanasekaran Danny , Jayaraman Muralidharan , Mannel Robert , Moore Kathleen , McMeekin Scott , Yang Da , Zuna Rosemary , Ding Kai , Tsiokas Leonidas , Bhattacharya Resham , Mukherjee Priyabrata 
Published: May 2017

AbstractCancer cells actively promote aerobic glycolysis to sustain their metabolic requirements through mechanisms not always clear. Here, we demonstrate that the gatekeeper of mitochondrial Ca2+ uptake, Mitochondrial Calcium Uptake 1 (MICU1/CBARA1) drives aerobic glycolysis in ovarian cancer. We show that MICU1 is overexpressed in a panel of ovarian cancer cell lines and that MICU1 overexpression correlates with poor overall survival (OS). Silencing MICU1 in vitro increases oxygen consumption, decreases lactate production, inhibits clonal growth, migration and invasion of ovarian cancer cells, whereas silencing in vivo inhibits tumour growth, increases cisplatin efficacy and OS. Mechanistically, silencing MICU1 activates pyruvate dehydrogenase (PDH) by stimulating the PDPhosphatase-phosphoPDH-PDH axis. Forced-expression of MICU1 in normal cells phenocopies the metabolic aberrations of malignant cells. Consistent with the in vitro and in vivo findings we observe a significant correlation between MICU1 and pPDH (inactive form of PDH) expression with poor prognosis. Thus, MICU1 could serve as an important therapeutic target to normalize metabolic aberrations responsible for poor prognosis in ovarian cancer.
Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity
Authors: Nguyen Thi-Huong , Medvedev Nikolay , Delcea Mihaela , Greinacher Andreas 
Published: May 2017

AbstractAntibodies recognizing complexes of the chemokine platelet factor 4 (PF4/CXCL4) and polyanions (P) opsonize PF4-coated bacteria hereby mediating bacterial host defense. A subset of these antibodies may activate platelets after binding to PF4/heparin complexes, causing the prothrombotic adverse drug reaction heparin-induced thrombocytopenia (HIT). In autoimmune-HIT, anti-PF4/P-antibodies activate platelets in the absence of heparin. Here we show that antibodies with binding forces of approximately 60–100 pN activate platelets in the presence of polyanions, while a subset of antibodies from autoimmune-HIT patients with binding forces ≥100 pN binds to PF4 alone in the absence of polyanions. These antibodies with high binding forces cluster PF4-molecules forming antigenic complexes which allow binding of polyanion-dependent anti-PF4/P-antibodies. The resulting immunocomplexes induce massive platelet activation in the absence of heparin. Antibody-mediated changes in endogenous proteins that trigger binding of otherwise non-pathogenic (or cofactor-dependent) antibodies may also be relevant in other antibody-mediated autoimmune disorders.