bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enantiomeric separation of six chiral pesticides that contain chiral sulfur/phosphorus atoms by supercritical fluid chromatography
Authors: Zhang Lijun , Miao Yelong , Lin Chunmian 
Published: January 2018

AbstractSix chiral pesticides containing chiral sulfur/phosphorus atoms were separated by supercritical fluid chromatography with supercritical CO2 as the main mobile phase component. The effect of the chiral stationary phase, different type and concentration of modifiers, column temperature, and backpressure on the separation efficiency was investigated to obtain the appropriate separation condition. Five chiral pesticides (isofenphos‐methyl, isocarbophos, flufiprole, fipronil, and ethiprole) were baseline separated under experimental conditions, while isofenphos only obtained partial separation. The Chiralpak AD‐3 column showed a better chiral separation ability than others for chiral pesticides containing chiral sulfur/phosphorus atoms. When different modifiers at the same concentration were used, the retention factor of pesticides except flufiprole decreased in the order of isopropanol, ethanol, methanol; meanwhile, the retention factor of flufiprole increased in the order of isopropanol, ethanol, methanol. For a given modifier, the retention factor and resolution decreased on the whole with the increase of its concentration. The enantiomer separation of five chiral pesticides was an “enthalpy‐driven” process, and the separation factor decreased as the temperature increased. The backpressure of the mobile phase had little effect on the separation factor and resolution.
Tourism demand analysis: The impact of the economic policy uncertainty on the arrival of Japanese tourists to the USA
Authors: Ongan Serdar , Gozgor Giray 
Published: January 2018

AbstractThis paper aims to investigate the effects of economic uncertainty on the Japanese tourists who travelled to the United States (USA) over the period 1996Q1–2015Q1. To achieve this aim, for the first time the Economic Policy Uncertainty index has been used as an independent variable in international tourism demand analysis models. The unit root and the cointegration tests have been applied to account for unknown structural breaks. Empirical findings indicate that one standard deviation increase in the Economic Policy Uncertainty index leads to a 4.7% decrease in the number of Japanese tourist arrivals to the USA in the long run.
Copolymerization of Epoxides and CO2 by Cobalt(II) Oxaporphyrins with Mechanistic Explorations on Poly(Propylene Carbonate) Formation
Authors: Xia Wei , Sun Xing‐Yu 
Published: January 2018

AbstractTwo cobalt(II) oxaporphyrins (OTPPCoCl and OTPPCoSbF6) are synthesized in this work and are characterized, including by X‐ray crystallography. Both complexes are tested as catalysts in the copolymerization of propylene oxide (PO)/cyclohexene oxide (CHO) and CO2. Polycarbonate is obtained in CHO/CO2 copolymerization with OTPPCoCl as a catalyst, whereas in the case of PO, cyclic carbonate (CC) is majorly formed. An anion exchange from Cl− to SbF6
− of the cobalt(II) oxaporphyrin leads to a drastic change in the product selectivity: sole polyether is afforded for both epoxides. The polyether formation by OTPPCoSbF6 is postulated to proceed via a cationic mechanism. Further, an equivalent admixture of OTPPCoCl and OTPPCoSbF6 allows the formation of poly(propylene carbonate). In this copolymerization, the latter catalyst acts as a PO activator, while OTPPCoCl functions as the initiator. In addition, density functional theory (DFT) calculations reveal a lower ring‐opening energy of PO by OTPPCoSbF6, compared with the usual propagating species, OTPPCo‐alkoxides and OTPPCo‐carbonates.
Biaxial Orientation of Poly(ethylene 2,5‐furandicarboxylate): An Explorative Study
Authors: van Berkel Jesper G. , Guigo Nathanaël , Kolstad Jeffrey J. , Sbirrazzuoli Nicolas 
Published: January 2018

AbstractThe biaxial orientation behavior of poly(ethylene 2,5‐furandicarboxylate) (PEF) is studied in comparison to poly(ethylene terephthalate) (PET). PEF is a polyester that can be produced through similar steps as PET but using 100% biobased 2,5‐furandicarboxylic acid instead of terephthalic acid. This work highlights the stress–strain behavior of PEF during biaxial orientation at various temperatures. Strain hardening and strain‐induced crystallization in the oriented PEF samples generally appeared at higher stretch ratios for PEF than for PET at comparable molecular weight, while somewhat lower degrees of crystallinity are reached in PEF. Shrinkage in oriented PEF is found to be on par with PET in the region of the glass transition. Higher modulus and improved barrier properties, compared to PET, are found in the oriented materials when sufficiently high stretch ratios are applied in biaxial orientation.
Resveratrol Potently Counteracts Quercetin Starvation‐Induced Autophagy and Sensitizes HepG2 Cancer Cells to Apoptosis
Authors: Tomas‐Hernández Sarah , Blanco Jordi , Rojas Cristina , Roca‐Martínez Joel , Ojeda‐Montes María José , Beltrán‐Debón Raúl , Garcia‐Vallvé Santiago , Pujadas Gerard , Arola Lluís , Mulero Miquel 
Published: January 2018

ScopeResveratrol (RSV) has been described as a potent antioxidant, antisteatotic, and antitumor compound, and it has also been identified as a potent autophagy inducer. On the other hand, quercetin (QCT) is a dietary flavonoid with known antitumor, anti‐inflammatory, and antidiabetic effects. Additionally, QCT increases autophagy. To study the hypothetical synergistic effect of both compounds, we test the combined effect of QCT and RSV on the autophagy process in HepG2 cells.Methods and resultsAutophagy is studied by western blotting, real‐time RT‐PCR, and cellular staining. Our results clearly indicate a bifunctional molecular effect of RSV. Both polyphenols are individually able to promote autophagy. Strikingly, when RSV is combined with QCT, it promotes a potent reduction of QCT‐induced autophagy and influences proapoptotic signaling.ConclusionRSV acts differentially on the autophagic process depending on the cellular energetic state. We further characterize the molecular mechanisms related to this effect, and we observe that AMP‐activated protein kinase (AMPK) phosphorylation, heme oxygenase 1 (HO‐1) downregulation, lysosomal membrane permeabilization (LMP), and Zinc (Zn2+) dynamics could be important modulators of such RSV‐related effects and could globally represent a promising strategy to sensitize cancer cells to QCT treatment.
Human Intestinal Dendritic Cells in Inflammatory Bowel Diseases
Authors: Bernardo David , Chaparro María , Gisbert Javier P. 
Published: January 2018

AbstractInflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a serious, costly, and persistent health problem with an estimated prevalence in Western countries around 0.5% of the general population; its socioeconomic impact is comparable with that for chronic diseases such as diabetes. Conventional treatment involves escalating drug regimens with concomitant side effects followed, in some cases, by surgical interventions, which are often multiple, mainly in Crohn's disease. The goal of finding a targeted gut‐specific immunotherapy for IBD patients is therefore an important unmet need. However, to achieve this goal we first must understand how dendritic cells (DC), the most potent antigen present cells of the immune system, control the immune tolerance in the gastrointestinal tract and how their properties are altered in those patients suffering from IBD. In this review, we summarize the current available information regarding human intestinal DC subsets composition, phenotype, and function in the human gastrointestinal tract describing how, in the IBD mucosa, DC display pro‐inflammatory properties, which drive disease progression. A better understanding of the mechanisms inducing DC abnormal profile in IBD may provide us with novel tools to perform tissue specific immunomodulation.
Measurement of long‐range heteronuclear coupling constants using the peak intensity in classical 1D HMBC spectra
Authors: Bigler Peter , Furrer Julien 
Published: January 2018

In this contribution, we show that the magnitude of heteronuclear long‐range coupling constants can be directly extracted from the classical 1D HMBC spectra, as all multiplet lines of a cross‐peak always and exclusively vanish for the condition Δ = k/nJCH. To the best of our knowledge, this feature of the classical HMBC has not yet been noticed and exploited. This condition holds true, irrespective of the magnitude and numbers of additional active and passive homonuclear nJHH′ couplings. Alternatively, the nJCH value may also be evaluated by fitting the peak's intensity in the individual spectra to its simple sin(πnJCHΔ)exp(−Δ/T2eff) dependence. Compared to the previously proposed J‐HMBC sequences that also use the variation of the cross‐peak's intensity for extracting the coupling constants, the classical HMBC pulse sequence is significantly more sensitive.
Medication use and association with urinary incontinence in women: Data from the Norwegian Prescription Database and the HUNT study
Authors: Mauseth Siri A. , Skurtveit Svetlana , Skovlund Eva , Langhammer Arnulf , Spigset Olav 
Published: January 2018

AimsTo investigate the association between medication use and urinary incontinence (UI) in women.MethodsIn a cross‐sectional population‐based study we analyzed questionnaire data on UI, including type and severity, from 21 735 women included in the Nord‐Trøndelag Health Study (HUNT) in Norway. These data were linked to data on filled prescriptions retrieved from the Norwegian Prescription Database. A multivariate logistic regression model was used to calculate the odds for having UI related to the number of filled prescriptions for selected drug groups during the 6 months prior to participation in HUNT, after adjustment for numerous confounding factors.ResultsSignificant associations with UI were found for selective serotonin reuptake inhibitors (SSRIs) and lamotrigine with OR 1.52 (1.30‐1.78) and 2.73 (1.59‐4.68) for two or more filled prescriptions. Both for SSRIs and lamotrigine, the associations were pronounced for mixed UI, whereas there were no clear‐cut increased risk of stress UI and urgency UI. The relations were strongest in women with the most severe symptoms. One filled prescription of antipsychotics, but not two or more, was also found to be related to UI with OR 1.91 (1.35‐2.71). No associations were found for benzodiazepines, zopiclone/zolpidem, beta blockers, and diuretics.ConclusionsThe odds for having UI were found to be about 1.5‐fold in women using SSRIs and almost threefold in women using lamotrigine. The association with lamotrigine has not been reported previously, and should be further evaluated in future studies.
Programming settings and recharge interval in a prospective study of a rechargeable sacral neuromodulation system for the treatment of overactive bladder
Authors: Blok Bertil , Van Kerrebroeck Philip , de Wachter Stefan , Ruffion Alain , Van der Aa Frank , Jairam Ranjana , Perrouin‐Verbe Marie , Elneil Sohier 
Published: January 2018

AimsThe RELAX‐OAB study is designed to confirm the safety, efficacy, and technical performance of the Axonics r‐SNM System, a miniaturized, rechargeable SNM system approved in Europe and Canada for the treatment of bladder and bowel dysfunction. The purpose of this article is to describe study subjects’ ability to charge the rechargeable neurostimulator and to document their neurostimulator program settings and recharge interval over time.MethodsFifty‐one OAB patients were implanted in a single‐stage procedure. These results represent the 3‐month charging experience for 48 subjects who completed the 3‐month follow‐up. Recharge intervals were estimated using therapy stimulation settings and subject experience was evaluated using questionnaires.ResultsForty‐seven of forty‐eight (98%) subjects were able to successfully charge their device prior to follow‐up within 1‐month post‐implant. At 3‐month post‐implant, 98% of subjects were able to charge prior to their follow‐up visit. Average stimulation amplitude across all subjects was 1.8 mA (±1.1 mA). A total of 69% of subjects had ≥14‐day recharge intervals (time between charging) and 98% of subjects had ≥7‐day recharge interval. No charging related adverse events occurred.ConclusionsStudy subjects were able to charge the Axonics r‐SNM System and stimulation settings provided 2 weeks of therapy between recharging for most subjects. Subject satisfaction indicates that subjects are satisfied with rechargeable SNM therapy.
The novel Axonics® rechargeable sacral neuromodulation system: Procedural and technical impressions from an initial North American experience
Authors: Elterman Dean S. 
Published: January 2018

AimsThe rechargeable Axonics® r‐SNM™ System is currently approved and available in Europe and Canada, with US FDA approval pending. This article provides a review of the system along with technique and technical considerations for its implantation based on my clinical experience with the new Axonics r‐SNM System.MethodsThe description of the surgical technique and technological considerations for the Axonics r‐SNM System is based my clinical experience of 11 cases performed at UHN Toronto Western Hospital.ResultsWhile the Axonics system is intended to provide similar therapy to the existing SNM system, the Axonics system has several new technological advances. Understanding these differences and optimizing surgical technique is anticipated to improve outcomes and patient experience.ConclusionsOverall the Axonics r‐SNM System and implant procedure requires minimal learning curve for experienced SNM implanters and provides several enhanced features for physicians and patients. Further experience by others may elucidate other nuances important to the implantation of this novel SNM system.
Patient‐controlled tissue collection for genetic testing after early pregnancy loss: A pilot study
Authors: Kucherov Alexander , Atrio Jessica , Williams Zev 
Published: January 2018

AbstractObjectiveTo determine how frequently and effectively products of conception can be obtained among women pursuing medical management of early pregnancy loss.MethodsThis pilot study was conducted to assess products of conception recovery outcomes for participants opting for medical management compared with women opting for surgical aspiration A tissue‐collection kit was provided to women opting for medical management. Outcome measures included successful collection of products of conception, quantity and integrity of DNA, and participant satisfaction with the process.ResultsTissue was collected from 19 of 22 participants in the medical management group (84%) and 39 participants (100%) in the surgical management group (P = .02). DNA yield and integrity were similar among both groups (P = .03 and P = .003, respectively). Participants in the medical group reported a high comfort level with the kit and the process of tissue collection.ConclusionsMedical management of a missed abortion followed by patient‐controlled collection of products of conception for subsequent cytogenetic analysis is well tolerated and highly effective. This methodology may reduce the need for surgical management, empower women to have more agency in their medical decisions, and increase access to genetic testing.
Evaluating Green Growth Practices: Empirical Evidence from China
Authors: Guo Lingling , Qu Ying , Wu Chunyou , Gui Shusen 
Published: January 2018

AbstractGreen growth has been identified as an effective way to foster economic growth and address environmental problems, and is practised in various countries globally. However, there remain several obstacles and difficulties to evaluating green growth practices in theory, as there is no proper evaluation framework. To bridge this gap, a universal and comprehensive evaluation indicator system for green growth is built based on improving the plan–do–check–action (PDCA) cycle method, and then is applied to study China's green growth practices by using a hybrid method combining fuzzy set theory and the Decision‐Making Trial and Evaluation Laboratory (DEMATEL) method. The influences and interrelationships of sub‐practices are determined, and a visual analysis is conducted to evaluate their relationships. The findings reveal that five sub‐practices were grouped into a set of causes. Of these, high‐level leadership (G1) is the largest influencing factor, and its support and consideration should be prioritized. The other 10 sub‐practices are classified as a set of effects. Of this set, a well‐governed and effective institutional arrangement (G5) is the most influential practice restricting China's green growth. Additionally, this paper also finds that communicating benefits with stakeholders (G7) is strongly related to other sub‐practices, and is the top factor contributing to the success of China's green growth strategy. This study contributes not only to the literature on green growth practices in an emerging economy but also to giving decision‐makers and researchers inside and outside China valuable inspiration and references for improving the performance of green growth practices. Copyright © 2018 John Wiley & Sons, Ltd and ERP Environment
Women's needs in new global sustainable development policy agendas
Authors: Nhamo Godwell , Muchuru Shepherd , Nhamo Senia 
Published: January 2018

AbstractThis paper provides an audit of how the needs of women are addressed in new global sustainable development policy agendas. The policy agendas audited include the 2030 Agenda for Sustainable Development (AfSD), the Paris Agreement and the Sendai Framework. An auditing matrix of 21 indicators was developed through a critical discourse analysis. Among the indicators identified were: violence against women; capacity building and access to technology; involvement in leadership and decision‐making; access to finance, land and other property ownership; inheritance; gender equality; and full access to job opportunities and equal pay. The main findings were that the development agendas address women and girls, although to varying degrees, with the 2030 AfSD emerging as outstanding in this regard. However, there were inherent weaknesses in the Paris Agreement and the Sendai Framework regarding land rights. Further work is needed in following up the promises from these development agendas.
Calcined Nickel‐Cobalt Mixed Metal Phosphonate with Efficient Electrocatalytic Activity for Oxygen Evolution Reaction
Authors: Feng Pingjing , Cheng Xian , Li Jintang , Luo Xuetao 
Published: January 2018

AbstractTransition metal phosphonates have recently gained attentions as efficient catalysts for oxygen evolution reaction (OER). In this paper, flower‐like nickel‐cobalt phenylphosphonate microspheres were sythesized, which could be used as excellent electrocatalyst for OER. After calcined at high temperature in air, resulted product of metal pyrophosphate exhibited outstanding electrocatalytic property. A small amount of carbon coming from the pyrolysis of phenylphosphonate were doped in matrix of metal pyrophosphonate, which promoted the OER catalysis by improving the electron transfer of material. Sample denoted as CoNiPP‐600 had the most excellent catalytic activity, with a current density of 10 mA/cm2 at a lower over‐potential of 264 mV, Tafel slope of 60 mV⋅dec−1 and superior durability in 1.0 M KOH solution.
Optimizing the Lithium Phosphorus Oxynitride Protective Layer Thickness on Low‐Grade Composite Si‐Based Anodes for Lithium‐Ion Batteries
Authors: Chen Chih-Jung , Mori Tatsuhiro , Jena Anirudha , Lin Hung-Yu , Yang Nai-Hsuan , Wu Nae-Lih , Chang Ho , Hu Shu-Fen , Liu Ru-Shi 
Published: January 2018

AbstractComposite materials containing Si as a component, are growing importance in the field of Li‐ion battery due to their extremely high theoretical capacity (3500 mAh g−1 at room temperature). However, the capacity of Si anode material decays dramatically because of serious volume variation during lithiation and delithiation process, which lead to deformation of Si electrode and resulted in poor cycle performance. In the present work, we have reported improved performance of modified Si electrode as an anode in Li‐ion battery. Si obtained from kerf‐loss slurry have been alloyed with Ni nanoparticles to improve its conductivity. A mechanistic study of the deposition of LiPON with respect to deposition pressure also presented. It is seen that LiPON layer serves as a protective layer with high ionic conductivity (1.38×10−6 S cm−1) to improve the electrochemical activity of Si−Ni electrode. The optimal 1st charge capacity of LiPON modified‐ Si−Ni composite was 915 mAh g−1 at a current density of 50 mA g−1 in a potential window of 1.2 V to 0.005 V. The charge capacity retained 56.2% of the initial cycle after 90th cycling measurement.
Quantitative Construction of C≡C Bond: Renaissance of Reductive Coupling of Benzotribromides Promoted by Cu/Polyamine
Authors: Ren Limei , Wang Qi 
Published: January 2018

AbstractQuantitative construction of carbon‐carbon triple bonds via reductive coupling of benzotribromides promoted by Cu/polyamine is realized under mild conditions. It provides a simple and efficient pathway to synthesize symmetrical diarylethynes using readily available and cheap reagents without acetylene group after simple workup.
High‐performance thin‐layer chromatography: An economical alternative for the quality control of medicinal plants and derived products
Authors: Kumar Dinesh , Sharma Upendra 
Published: January 2018

AbstractCurrently, delicious and essential items are intentionally diluted to gain higher profit in the market. Awareness about the quality of naturally derived products such as food, nutrients, cosmetics, and drugs has increased. An economical method for their quality assessment is needed. In this regard, high‐performance thin‐layer chromatography is an inexpensive, fast, and reproducible technique for quality control. The basics of thin‐layer chromatography and high‐performance thin‐layer chromatography have been reviewed previously, but a comprehensive compilation of its applications is lacking. The current review focuses on high‐performance thin‐layer chromatography based analytical methods for the quality assessment of various plant species, plant materials, plant‐derived products, food and nutrients, and cosmetics (natural origin). This review covers all aspects of high‐performance thin‐layer chromatography and will prove fruitful for research and development in academia and industry.