bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling surge dynamics improves coastal flood estimates in a global set of tropical cyclones
Authors: Vogt Thomas , Treu Simon , Mengel Matthias , Frieler Katja , Otto Christian 
Published: September 2024

AbstractTropical cyclone-induced storm surge is a major coastal risk, which will be further amplified by rising sea levels under global warming. Here, we present a computational efficient, globally applicable modeling approach in which ocean surge and coastal inundation dynamics are modeled in a single step by the open-source solver GeoClaw. We compare our approach to two state-of-the-art, globally applicable approaches: (i) using a static inundation model to translate coastal water level time series from a full-scale physical ocean dynamics into inundated areas, and (ii) a fully static approach directly mapping wind fields to inundation areas. For a global set of 71 storms, we compare the modeled flooded areas to satellite-based floodplain observations. We find that, overall, the models have only moderate skill in reproducing the observed floodplains. GeoClaw performs better than the two other modeling approaches that lack a process-based representation of inundation dynamics. The computational efficiency of the presented approach opens up new perspectives for global assessments of coastal risks from tropical cyclones.
The human disease-associated gene ZNFX1 controls inflammation through inhibition of the NLRP3 inflammasome
Authors: Huang Jing , Wang Yao , Jia Xin , Zhao Changfeng , Zhang Meiqi , Bao Mi , Fu Pan , Cheng Cuiqin , Shi Ruona , Zhang Xiaofei , Cui Jun , Wan Gang , Xu Anlong 
Published: September 2024

AbstractInherited deficiency of zinc finger NFX1-type containing 1 (ZNFX1), a dsRNA virus sensor, is associated with severe familial immunodeficiency, multisystem inflammatory disease, increased susceptibility to viruses, and early mortality. However, limited treatments for patients with pathological variants of ZNFX1 exist due to an incomplete understanding of the diseases resulting from ZNFX1 mutations. Here, we demonstrate that ZNFX1 specifically inhibits the activation of the NLR family pyrin domain-containing protein 3 (NLRP3) inflammasome in response to NLRP3 activators both in vitro and in vivo. ZNFX1 retains NLRP3 in the cytoplasm and prevents its accumulation in the TGN38 + /TGN46+ vesicles in the resting state. Upon NLRP3 inflammasome activation, ZNFX1 is cleaved by caspase-1, establishing a feed-forward loop that promotes NLRP3 accumulation in the trans-Golgi network (TGN) and amplifies the activity of the downstream cascade. Expression of wild-type ZNFX1, but not of ZNFX1 with human pathogenic mutations, rescues the impairment of NLRP3 inflammasome inhibition. Our findings reveal a dual role of ZNFX1 in virus sensing and suppression of inflammation, which may become valuable for the development of treatments for ZNFX1 mutation-related diseases.
A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets
Authors: Angara Rajendra Kumar , Sadi Arif , Gilk Stacey D 
Published: September 2024

AbstractEffective intracellular communication between cellular organelles occurs at dedicated membrane contact sites (MCSs). Tether proteins are responsible for the establishment of MCSs, enabling direct communication between organelles to ensure organelle function and host cell homeostasis. While recent research has identified tether proteins in several bacterial pathogens, their functions have predominantly been associated with mediating inter-organelle communication between the bacteria containing vacuole (BCV) and the host endoplasmic reticulum (ER). Here, we identify a novel bacterial effector protein, CbEPF1, which acts as a molecular tether beyond the confines of the BCV and facilitates interactions between host cell organelles. Coxiella burnetii, an obligate intracellular bacterial pathogen, encodes the FFAT motif-containing protein CbEPF1 which localizes to host lipid droplets (LDs). CbEPF1 establishes inter-organelle contact sites between host LDs and the ER through its interactions with VAP family proteins. Intriguingly, CbEPF1 modulates growth of host LDs in a FFAT motif-dependent manner. These findings highlight the potential for bacterial effector proteins to impact host cellular homeostasis by manipulating inter-organelle communication beyond conventional BCVs.
Analytical Separation Science
Authors: Pirok Bob W J , Schoenmakers Peter J 
Published: September 2024

There is a pervasive need for analytical separations in many fields of science and in many different industries. Analytical measurements are vital to understand processes and materials, to develop or improve products and to protect the health of individuals and entire ecosystems. Separations are needed in many situations because most samples are (complex) mixtures. Thus, scientists in academia and industry need analytical separations.
This book teaches (almost) all the important aspects of analytical separation science to students and practicing analysts at various points in their careers. For those new to separation science, it features basic modules in which fundamental concepts and analytical practice are described. Master modules provide more in-depth treatments intended for graduate students. Advanced modules bring the reader to the current frontiers of separation science and encourage further reading.
Emphasis is on the main analytical separation techniques of gas chromatography, liquid chromatography and capillary electrophoresis, but due attention is paid to a number of other methods and to sample preparation. Knowledge on statistics and chemometrics is provided, so that separation scientists can obtain relevant information from analytical data. Finally, the book describes how a sound understanding can be used to successfully develop optimal separation methods.
Bubbles and drops between circular frames: shape, force and stability analysis
Authors: Walzel Friedrich , Dijoux Jonathan , Jacomine Leandro , Harle Élodie , Muller Pierre , Charitat Thierry , Drenckhan Wiebke 
Published: September 2024

Combining experiments, simulations and theory, we provide a complete shape analysis of two bubbles held by circular frames in the parameter space of different frame radii, distances between frames and contact angle between bubbles (0°, 60° and 90°).
Agile working and job satisfaction for localization language agents
Authors: Kassawat Madiha 
Published: September 2024

Abstract
The localization industry has developed at the levels of content, technology and workflow. While agility can describe any virtual job nowadays, its application in localization should be highlighted, since agile working is now widely adopted in developer teams. Job satisfaction has been researched within translation studies, sociology of work and organizational research. This article addresses the impact of agile working in localization, as a virtual and IT-related domain, on the job satisfaction of localization language agents. It is based on a survey and tackles agile working aspects that are relevant to the translation workflow in localization. It also borrows key job satisfaction elements from other domains, which can reveal understudied areas in our domain. The results show, for example, a positive relationship between job satisfaction and in-process and in-team recognition, as well as autonomy. Job satisfaction is lower when there is a lack of context or small-size projects.
Long-Lifetime Optical Trapping of a 40Ca+ Ion
Authors: Chen 陈 Zheng 正 , Wang 王 Miao 淼 , Zhang 张 Baolin 宝林 , Zhang 张 Huaqing 华青 , Ma 马 Zixiao 子晓 , Hu 胡 Ruming 如明 , Huang 黄 Yao 垚 , Gao 高 Kelin 克林 , Guan 管 Hua 桦 
Published: September 2024

Abstract
We have experimentally achieved the all-optical trapping of a 40Ca+ ion. An optical dipole trap was established using a high-power, far-detuned, tightly focused laser with a wavelength of 532 nm. The single 40Ca+ ion was trapped without any RF fields and demonstrated a long lifetime of over 3 s. In this experiment, we implemented several measures to improve the optical trapping probability, including focusing the dipole beam waist near the diffraction limit, precisely compensating for stray electric fields, and mitigating electron shelving in metastable states. The optical trapping of a 40Ca+ ion eliminates the influence of micromotion induced by RF fields, potentially paving the way for development of all-optical trapping ion optical clocks.
Effects of Nb doping on the thermoelectric performance of CuI doped n-type Bi2Te3
Authors: Marekwa Innocent Thato , Kihoi Samuel Kimani , Kahiu Joseph Ngugi , Kim Hyunji , Shin Dong Hyun , Lee Ho Seong 
Published: September 2024

Abstract
The thermoelectric (TE) properties of Nb-doped (CuI)0.003Bi2−x
Nb
x
Te2.7Se0.3 compounds (x = 0, 0.005, 0.01 and 0.03), were investigated at temperatures ranging from 300 to 600 K. Among the compounds studied, the lightly substituted (CuI)0.003Bi1.995Nb0.005Te2.7Se0.3 compound exhibited the best TE performance due to the improvement in its electrical conductivity and its relatively unchanged Seebeck coefficient due to Nb doping. Its figure of merit, ZT, was greater than the undoped (CuI)0.003Bi2Te2.7Se0.3 compound for the temperature range investigated. In particular, the ZT of (CuI)0.003Bi1.995Nb0.005Te2.7Se0.3 reached a value of 0.65 at 448 K in this study.
Percolation network study of highly sensitive buckled elastomeric piezoresistive sensors
Authors: Alidoust Alireza , Ansari Reza , Haghgoo Mojtaba 
Published: September 2024

Abstract
Flexible pressure sensors are needed for future artificial electronic skin applications. Carbon black (CB)-enhanced elastomers are known for their unique conductivity, allowing for special uses in sensor technology. This research analyzes the sensitivity of elastomeric sensors reinforced with CB, under a pre-strained buckle, using a modified percolation network model to enhance performance in sensing applications. The finite element method is employed to analyze the piezoresistive characteristics of the sensors across various thicknesses. The research involves analyzing the strain patterns of buckled piezoresistive sensors when an indenter applies a load, and how this influences the sensors’ resistivity. The mechanical parameter is directly correlated to the sensor sensitivity through the maximum principal strain. The model shows a good agreement with the experimental data. The pressure sensitivity resulting from indenter compressive contact is 0.03 and 0.0061 kPa−1 in the pressure range of 0–1 and 0–5 kPa for wavy and straight 1000 μm buckled sensors, respectively. The results show that the film with 50% taller waves has a 40%–60% narrower pressure sensing ranges. Moreover, results indicate that adding waves to the geometry of the sensor improves the piezoresistive behavior by increasing the relative displacements of edges. Results also reveal more stable performance from fewer waves and a higher working range by thicker sensors.
Damage sensing in multi-functional nanocomposite polymer bonded energetics with embedded multi-walled carbon nanotube sensing networks
Authors: Shirodkar Nishant , Talluru Viswajit , Seidel Gary D 
Published: September 2024

Abstract
This experimental investigation evaluates the strain and damage sensing abilities of multi-walled carbon nanotube (MWCNT) networks embedded in the binder phase of polymer-bonded energetics (PBEs). PBEs are a special class of particulate composite materials that consist of energetic crystals bound by a polymer matrix, wherein the polymer matrix serves to maintain the composite’s shape and form. The structural health monitoring (SHM) approach presented in this work exploits the piezoresistive properties of the distributed MWCNT networks. Major challenges faced during such implementation include the low binder concentrations of PBEs, the presence of conductive/non-conductive particulate phases, the high degree of heterogeneity in the PBE microstructure, and achieving the optimal MWCNT dispersion. In this study, ammonium perchlorate (AP) crystals as the oxidizer, Aluminum grains as the metallic fuel, and Polydimethylsiloxane (PDMS) as the binder are used as the constituents for fabricating PBEs. To study the effect of each constituent on the MWCNT network’s SHM abilities, various materials systems are comprehensively studied: MWCNT/PDMS materials are first evaluated to study the binder’s electromechanical response, followed by AP/MWCNT/PDMS to assess the impact of AP addition, and finally, AP/AL/MWCNT/PDMS to evaluate the impact of adding conductive aluminum grains. Compression samples (ASTM D695) were fabricated and subjected to monotonic compression. Electrical resistance is recorded in conjunction with the mechanical test via an LCR meter. Gauge factors relating to the change in normalized resistance to applied strain are calculated to quantify the electromechanical response. MWCNT dispersions and mechanical failure modes are analyzed via scanning electron microscopy imaging of the fracture surfaces. Correlations between the electrical behavior in response to the mechanical behavior are presented, and possible mechanisms that influence the electromechanical behavior are discussed. The results presented herein demonstrate the successful ability of MWCNT networks as SHM sensors capable of real-time strain and damage assessment of PBEs.
System identification and landscape stability of stochastic competition ecosystem
Authors: Zhang Hongxia , Lei Youming , Xu Wei 
Published: September 2024

Abstract
Motivated by the challenging issue in analyzing the stochastic stability from observed state time series in a competition ecosystem, we take a systematic study from system identification to landscape stability. The vector field manifold is utilized to discuss dynamic properties of the deterministic competition ecosystem. For the stochastic state time series, we integrate the stochastic Koopman operator, the Kolmogorov backward equation and the extended dynamic mode decomposition methods to approximate the drift expression, while the Kramers–Moyal formula is used to identify the noise intensity. The depth and width indicators of the energy landscape are constructed to verify the effectiveness of the system identification method and to examine the impact of noise on system stability. Results demonstrate that proposed indicators can effectively assess the stochastic stability. Moreover, we find the environmental disturbance can induce global instability of the stochastic competition system, but its relative stability impact on each potential well will be altered by species competitiveness.
Towards sustainable built environment: learning from socio-economic characteristics, housing norms and satisfactions of three settlement patterns in Semarang City, Indonesia
Authors: Manaf Asnawi , Irwansyah Mirza 
Published: September 2024

Abstract
his article presents the results of a comparative study of socio-economic characteristics, housing norms, and satisfaction of low-income families living in three different settlement patterns as a perspective toward the sustainable built environment in Semarang City, Indonesia. The research used the survey method to examine households living in Kaligawe low-cost rental flats, informal settlements, and landed houses near the Kaligawe flats. Data were obtained by distributing questionnaires to 97 respondents selected using a simple random sampling technique. The findings indicated that although respondents showed differences in housing satisfaction (performance) and housing deficits, they showed similarities in housing norms (importance). Thus, although their socioeconomic characteristics were generally different, their housing norms were similar. Based on an importance-performance analysis, the study offers recommendations regarding which aspects of housing and residential environments should be prioritized to support a sustainable housing-built environment. This study encourages policy-makers to prioritize aspects of the dwelling unit’s physical condition and the neighborhood environment’s livability in improving the quality of low-income housing in Semarang. The current study provides evidence of the complexity of the housing strategies used by households to meet their housing needs, especially in affordable housings. This is closely related to socio-economic characteristics, which is delve into sustainable built environment.
Exploring the opportunities for biophilic design application in urban pedestrian environments in China under the context of climate change: a perspective of affective experience
Authors: Li Kunyu , Abidin Nor Arbina Zainal , Mohamad Diana 
Published: September 2024

Abstract
Rapid urbanization has led to the urban heat island effect (UHI), exacerbating cities’ extreme temperatures and air pollution, thereby threatening residents’ well-being. To address this issue, many countries are utilizing green infrastructure to improve urban walking environments, promote walking, mitigate climate change, and reduce the impact of UHI. However, pedestrian landscape design often overlooks residents’ emotional needs and experiences. Biophilic Design (BD) offers a solution by promoting positive interactions between people and nature in urban environments, enhancing residents’ emotional connection with nature. This paper, focusing on densely populated and highly urbanized China, employs systematic literature review and text analysis methods to summarize affective experiential (AE) factors that positively influence residents’ walking intentions and corresponding environmental and landscape features. Based on this, a preliminary framework for applying Biophilic Design in urban pedestrian environments is proposed, aiming to provide scientific guidance for developing Biophilic Pedestrian Landscape Design (BPLD) schemes to enhance residents’ willingness to walk. Although specific guidelines for implementing biophilic walking landscapes in urban environments are lacking, their potential to improve urban livability and residents’ well-being is evident.
Micro, small, and medium enterprises (MSME) to promote sustainability of urban kampongs and cultural landscape in Semarang City-Indonesia: an examination on the typology
Authors: Sundaro Hendrianto , Rudiarto Iwan , Handayani Wiwandari , Febriyanto Ahady Farrel 
Published: September 2024

Abstract
Urban Kampongs are a typical settlement characterized by high density and poor infrastructure facilities in many developing countries, including Indonesia. The inhabitants are known to have strong social cohesion and kindship. In Semarang, the kampongs are widely spread in city centers. Located in the city hotspot, its existence is threatened, replaced by various commercial and modern urban activities. On the other hand, the increasingly massive development of the city offers opportunities to further strengthen the existence of urban kampong through strengthening the MSMEs, promoting the city with more locally based economic activities. Accordingly, sufficient comprehension of the kampong characteristics is needed mainly to maintain sustainability landscape and cultural urban kampong. This research aims to examine the typology of MSME-based urban kampongs in Semarang City. Overlay and density analyses are used to determine the location of MSME-based urban kampongs, while descriptive analysis is used to further explore the typology, which is linked to MSME activities in production and location aspects. The research results show three typologies of MSMEs-based urban kampongs in Semarang City: 1) Culinary kampongs, 2) Warungan kampongs, and 3) Groceries kampongs. These typologies can provide a better understanding of promoting the sustainability of urban kampongs and cultural landscapes.
Experimenting ‘gentle density’: using plot sizing tool to blend missing middle housing into existing neighborhoods in Tanah Abang TOD
Authors: Wellsan A , Harianto D J 
Published: September 2024

Abstract
Jakarta’s rapid growth and urbanization necessitate urgent demand for affordable housing that is well-connected to public transport and access to basic amenities. The lack of housing diversity poses challenges to sustainable urban growth, exacerbates traffic congestion, and limits housing choices. This research addresses the urgency of experimenting with density in Jakarta’s existing neighborhoods in the TOD area by focusing on the constraints depicted by existing regulatory frameworks, zoning restrictions, and potential community resistance. With Tanah Abang TOD as a pilot project, this paper outlines an approach to produce the most optimal design with parametric software of Rhino and Grasshopper ecosystem to compute various typologies of Missing Middle Housing in existing neighborhoods. While the computational ecosystem measures the performance of the design iterations, several dimensionalities are displayed in service coverage from transportation nodes, visibility index among the human visibility field, and cost affordability through the estimated cost of development. Ultimately, the methodology this paper provides can be also experimented with in other places with similar urban structures.
AI-enhanced smart urban design process for salutogenic residential area: the case of Capital City of Nusantara (IKN)
Authors: Gunawan Kelvin N. , Kartikasari Damara , Gumilar Jasin , Nolasari Annisa B. , Sugangga Marisa 
Published: September 2024

Abstract
Urban areas play a crucial role as a space that fulfills the human basic needs and activities, including providing healthy and suitable living environments for its inhabitants. However, future challenges facing cities have the potential to render cities increasingly uninhabitable, thereby threatening both the health and sustainability of their environment. This research aims to develop the design of residential areas with an emphasis on environmental feasibility and health through a salutogenic approach. In addition, this research also identifies AI methods and approaches in the urban design process to achieve salutogenic approaches. Research method in this research utilizes exploratory qualitative approach and literature review to understand the principles of design with a salutogenic approach and uncover the potential of contemporary AI in urban design. Conducted within the Residential Area of Ibu Kota Nusantara (IKN), the research shows AI accelerates the design process using a salutogenic approach, supporting Indonesia’s Smart and Sustainable Forest City concept. The design concept is termed “Toward Tomorrow’s Sanctuary,” encompassing four main missions: sustainability, humans, nature, and technology. The design output features biomimetic and vernacular building concepts, a 10-minute city with multilevel pedestrian circulation, and green infrastructure with renewable energy sources. While AI significantly contributes to the urban design process, the importance of human considerations remains the primary focus. This will ensure that the design outcomes align with expectations, local contexts, and considerations of ethical aspects.