bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Retrospective Analysis of the Real-Life Utilization of Ranibizumab in Patients with Wet Age-Related Macular Degeneration from Portugal
Authors: Silva Rufino , Goncalves Carla , Meireles Angela , Teixeira Carla , Rosa Paulo , Monteiro-Grillo Manuel , Canelas Joaquim , Carneiro Angela , Flores Rita 
Published: July 2017

Introduction: Anti-vascular endothelial growth factor therapy has revolutionized the treatment of wet age-related macular degeneration; however, it is important to monitor actual use of ranibizumab and related treatment outcomes in routine practice.Material and Methods: This was a retrospective, observational study to monitor the 2-year outcomes following ranibizumab treatment for wet age-related macular degeneration in Portugal. Patients treated between January 2009 and December 2009 were retrospectively evaluated. All decisions were made by the treating physician in accordance with their usual routine clinical practice. The primary assessment was mean change in visual acuity score using Early Treatment Diabetic Retinopathy Study or Snellen equivalent.Results: A total of 128 patients with wet age-related macular degeneration were analyzed (mean age 79.4 years; mean visual acuity score 54.2 letters). Mean change in visual acuity score from baseline was –1.6 letters (n = 82) at year one and –5.1 letters (n = 72) at year two. The mean number of ranibizumab injections was 3.8 (year one) and 1.6 (year two). On average, patients attended 8.6 and 5.0 visits and optical coherence tomography was used in 75.0% of patients in year one and in 56.3% of patients in year two, respectively.Discussion: Despite a relatively high number of visits, including monitoring visits and use of optical coherence tomography - guided therapy, few injections were administered and visual acuity was not improved.Conclusion: These findings indicate that as-needed treatment resulted in under-dosing in a real-life setting in Portugal. Such limitations may also be related to increasing numbers of patients, resulting in clinic saturation.
A PERCEPÇÃO DO ALUNO SOBRE OS CURSOS ONLINE
Authors: Losada Analía Verónica , Brito Gisana Nascimento 
Published: July 2017

Este artigo propõe a discussão sobre como os alunos ingressantes da graduação presencial estão percebendo a educação online fazendo um breve perfil dos mesmos. A pesquisa baseia-se em um questionário aplicado a 129 alunos ingressantes da graduação presencial, de seis cursos presenciais: Jornalismo, Pedagogia e Direito – Humanas; e Arquitetura, Engenharia Elétrica e Engenharia Civil - Exatas; da Universidade Federal do Tocantins na cidade de Palmas-TO. Por meio do questionário foi possível conhecer a percepção dos alunos em relação à Educação Online. Trata-se de um estudo exploratório de caso. Pelos resultados apurados, identificou-se que em geral a percepção dos alunos foi negativa, em especial, as percepções quanto ao rigor acadêmico, fraudes e plágio.

PALAVRAS-CHAVE: Percepção Discente; Educação Online; Educação Superior.

ABSTRACT
This article proposes a discussion about how undergraduate students in face-to-face education are perceiving online education by making a brief profile of these students. The research is based on an exploratory case study developed with 129 undergraduate students from six undergraduate programs in Journalism, Pedagogy, Law, Architecture, Electrical Engineering and Civil Engineering at the Tocantins Federal University in Palmas-TO. The methodology was developed through the application and analysis of a questionnaire to the 129 students. Results show that students perception is mostly negative, specially their perceptions regarding academic rigor, fraud and plagiarism.
O USO DO PLANEJAMENTO ESTRATÉGICO SITUACIONAL (PES) EM UNIVERSIDADES PÚBLICAS: O caso da Pró Reitoria de Avaliação e Planejamento da Universidade Federal do Tocantins
Authors: Duarte Michelle Trombini , Nascimento Jasiel , Rodrigues Waldecy 
Published: July 2017

Este artigo apresenta a aplicação da metodologia do Planejamento Estratégico Situacional (PES) na Pró Reitoria de Avaliação e Planejamento (PROAP), e os primeiros resultados deste processo. Entende-se que é necessário ressaltar que este planejamento deve ser dinâmico, e de um modo geral adaptar-se a dinâmica do ambiente interno e externo, e de modo especial à dinâmica das pessoas. Por este motivo tão importante quanto a realização do planejamento é seu monitoramento a fim de promover ajustes que aumentem a capacidade de realizar sua visão de futuro.
Predicting the effect of water quality on water distribution cast iron and steel pipes using two novel indices
Authors: Philibert Marc , Mendaza Sofia , Zraick Flavia , Rabaud Benjamin 
Published: July 2017

Abstract
The internal corrosion of cast iron and steel pipes is one of the main issues that drinking water distribution operators are facing. This study evaluated the relevance of 10 known corrosion indices according to their estimate of corrosion rate and iron particle release for 20 different water qualities. Pilot-scale contact trials were run over 45 days using cast iron and steel coupons. Corrosion rate was measured by coupon weight-loss and by an online linear polarization rate probe. Particle release was monitored by an online turbidimeter. The results showed that none of the indices properly predicted the level of risk associated with each water and that corrosion and particle release were not correlated. Two novel indices were developed to predict the corrosion and particle release risks independently of each other. The corrosion index showed a strong linear correlation with the corrosion rate of cast iron and slightly less reliable results for steel. The Particle Emission Index presented good correlation with turbidity in waters following contact with cast iron. These two indices thus showed interesting potential as tools to limit internal corrosion risks for metal pipes in water distribution networks.
SEARCHING ANTIVIRAL DRUGS FOR EBOLA VIRUS FROM PHYTO-CONSTITUENTS OF AZADIRACHTA INDICA: APPLICATION OF MOLECULAR MODELING STUDIES
Authors: Parasuraman P , R Suresh , P Perumal 
Published: July 2017

ABSTRACTThe current objective of the study is to identify some naturally occurring product from Azadirachta indica and evaluate its binding activity against VP24 protein as Ebola virus target through in silico docking studies. Reported phytoconstituents of Azadirachta indica were prepared for docking evaluation using Brincidofovir as the standard. In silico docking studies were carried out using GLIDE (Grid-based Ligand Docking with Energetics) is a ligand binding program provided by Schrödinger. These results showed that all the selected phytoconstituents showed binding energy ranging between -7.95 kcal/mol to -1.54 kcal/mol when compared with that of the standard (-6.06 kcal/mol). Naturally occurring products Catechin, Epicatechin, Gallic acid and Nimbolide are potential than the standard brincidofovir but Azadirachtin, Margolonone, Mahmoodin, Isomargolonone, Gedunin, Margolone, Nimbidin and Nimbin have low binding affinity towards target when compared with the standard. These molecular docking analyses of phytoconstituents of Azadirachta indica could lead to the further development to identify the potent drugs for the treatment of Ebola virus. KEYWORDS: Azadirachta indica, VP42 protein, Ebola virus, in silico docking.
ASSESSMENT OF FEASIBILITY AND COMPLICATIONS OF LAPAROSCOPIC CHOLECYSTECTOMY IN CIRRHOTIC PATIENTS
Authors: Goyal Nitin , Pandey Anshuman , Masood Shakeel , Chauhan Smita , Gupta Alankar , Noman Khalid 
Published: July 2017

Abstract :Introduction: From the era of absolute contraindication to the phase of preferred treatment, the technique of laparoscopic cholecystectomy advances with time. Here, we report our experience of laparoscopic cholecystectomy in 20 patients of liver cirrhosis. In our institute, laparoscopic cholecystectomy is the preferred choice for cholelithiasis in cirrhotic patient.Methods: In last 2 years, 180 laparoscopic cholecystectomies were performed and 20 patients were cirrhotic. Their data analyzed retrospectively in terms of preoperative optimization, operative technique and results.Results: Laparoscopic cholecystectomy was completed successfully in 19 patients and one was converted to open. Mean operative time was 54 minutes. No additional port was required in all cases. Calot’s first dissection was performed in 18 patients and fundus first technique was used in 2 patients due to unclear anatomy. Liver bed bleeding was present in 16 patients, which was controlled effectively. Subhepatic drain was placed in 12 patients. There was no mortality. Morbidity in two patients was worsening of ascites in one; and incisional hernia in other patient which was converted to open. Port site complications were not noted in any patient and there was no evidence of intraabdominal bleeding or bile leak postoperatively. Blood and component transfusion was required in 2 patients. Average length of hospital stay was 4.8 days.Conclusion: Though laparoscopic cholecystectomy may be difficult in cirrhotic patients but it is feasible and relatively safe. It offers many advantages in cirrhotic patients and associated with low morbidity when compared with open surgery.Keywords: cirrhosis, laparoscopic cholecystectomy, difficult cholecystectomy
La ciudad armoniosa. Comentario a “Habitar la ciudad” de Juan Carlos Mansur
Authors: Rosales Meana Diego Ignacio 
Published: July 2017

<p>Recibido: 01/02/2017 • Aceptado: 15/10/2017</p><p>En este artículo me propongo comentar los conceptos y argumentos centrales del texto “Habitar la ciudad” de Juan Carlos Mansur. En la primera parte del texto comento las nociones de “arraigo”, “ciudad” y “proximidad” a partir de las intuiciones que algunos filósofos han tenido sobre ellos (S. Weil, M. Zambrano o Hesíodo). En la segunda parte, intento argumentar a favor de la idea de que la habitación más primaria es la que ocurre en la intimidad de la persona, y de ahí parte hacia el exterior, comenzando con la habitación propia, luego la casa, más tarde el barrio y, finalmente, la ciudad. Concluyo con la puesta sobre la mesa de algunos problemas de la ciudad contemporánea y apunto algunas ideas que sugieren el camino hacia el que tendría que ir el ciudadano y el arquitecto para hacer la de la ciudad un sitio habitable.</p><p class="Cuerpo"> </p>
Modeling, Controller Design and Simulation of Power System Friendly Power Supply
Authors: A. P.N. Tekwani  , B. G.N. Khanduja  
Published: July 2017

The paper is based on the performance comparison of single-phase diode-bridge rectifier and the proposed front-end converter in terms of the Total Harmonic Distortion (%THD) of the line current, power factor of the system and ability of energy saving of the converter by capability of reverse power flow action. The parameters of the voltage control-loop for proposed converter are derived by two methods named Unity Modulus (Magnitude Optimum) method and Ziegler-Nichols method. The parameters obtained from both the methods are compared by the mathematical model for forward and reverse power flow mode of operation. The model is generated in Simulink toolbox of MATLAB and results are obtained for steady state, transient and dynamic conditions. It is observed that the unity power factor is maintained during all the conditions for various loads. Drastic reduction in %THD of input current waveform is obtained in proposed power supply with an added advantage of regenerative capability. For comparison of results of control-loops, a programming file (M-file) is also generated in MATLAB and from the same file the step-response and Nyquist plots are obtained for system control-loops. The experiment results are also obtained for the prototype converter in inverter mode. The power system friendliness of the proposed front-end converter is quite evident from the results presented in the paper.
A Study of the Current Disturbance Caused by Wind Induced Vibrations of Photovoltaic Modules
Authors: J. Schmid  , E. Kancsar  , M. Drapalik  , V. Schlosser  , G. Klinger  
Published: July 2017

Mechanical vibrations of a solar module mount-ing rack cause oscillations in the orientation of the module towards the sun. The resulting intensity oscillations of the incident light originate an a.c. current at the module’s termi-nals. We have investigated this effect in the laboratory by means of a vibration table and outdoors where wind forces induce vibra-tions to the mounting rack. Although the collected results are specific and restricted to our experimental set up and environ-mental situation we deduce that vibration induced current tran-sients and oscillations of a solar module’s output most often will be the dominant origin of distortion in the low frequency regime.
PENGEMBANGAN MODEL PEMBELAJARAN MATEMATIKA SMP KELAS VII BERBASIS KEHIDUPAN MASYARAKAT JAWARA (JAWA DAN MADURA) DI KABUPATEN JEMBER
Authors: Suwito Abi , Trapsilasiwi Dinawati 
Published: July 2017

<em>This research is meant to develop innovative teaching equipment which able to improve as well as conserve the culture through Mathematics learning. Learning equipment which is developed are in the form of students’ book and LKS (Student’s Work Book) of Mathematics subject of VIIth grade concerning with the culture of Javanese and Maduries who lives in Jember district. This developmental study is planned in three steos, namely; theorethical study and needs analysis, formulation of learning equipments, as well as testing the equipments and eksperiment. The Model used in this research is developmental model of ADDIE, which divided into 5 phases, namely; Analysing, Designing, Developing, Implementing and Evalualing. The subject of this research are three students of VII grade of SMP (Junior High School). The product of this research is students book which based on Javanese and Maduries culture. The result of this research shows that students’ learning test in Squares subject based on Javanese and Maduries culture are good, with rate of 83,33. It can be conclude that students’ book of VII SMP which based on Javanese and Maduries culture in Squares Shapes material are effective to be used in teaching.</em>
KONSTRUKSI TES KEBAHASAAN UAS SD DI KABUPATEN MADIUN
Authors: Samsiyah Nur , Sari Apri Kartika , Emilia Chrisna 
Published: July 2017

<p>Language learning is aimed to achieve proficiency properly. To achieve objectives of language learning cannot be separated from aspects of grammar. One way to achieve the grammatical aspect is by using a test. The purpose of language test is ability and skill in language not knowledge about language. Range of aspects are measured based on the types of tests used in the test questions at the end of the learning/ formative. This research aimed to determine language aspects tested at the end of each semester. This study used a qualitative approach and data sources in the form of the exam end of semester 1 and 2 grade 1 to grade 6. Techniques of data collection is done by collecting data source in the field and read the data source. Data analysis phase consists of three stages: data reduction, classification, presentation of data and drawing conclusions. The results showed there were aspects of language such as phonology, morphology aspect which consists of free and bound morpheme, the process of reduplication or repetition, syntactic aspects that form phrases and sentences as well as aspects such as semantic meaning.</p><p> </p><p> </p>
PEMBELAJARAN MATEMATIKA REALISTIK PADA MATERI PENJUMLAHAN DAN PENGURANGAN BILANGAN BULAT BAGI SISWA KELAS IV SEKOLAH DASAR
Authors: Kurniawati Rissa Prima 
Published: July 2017

<p>Mathematics has characteristic in good abstract object. That cause students have difficulty in understanding of mathematics. Therefore, the real-life experiences of children in the classroom are important for learning and students will understand the material quickly. This study is aimed to describe the activities of students during the learning process that takes place in the material realistic arithmetic addition and subtraction and describe the learning completeness students after being taught with realistic learning the material arithmetic addition and subtraction of integers. This type of research used in this research is qualitative research. Subjects in this study were students of class IV SDN Jenangan, Kwadungan, Ngawi.Based on this research, student activities relevant to teaching (teaching and learning) of 98.83% classified in the category very well. While the student activity which is not relevant to the teaching of 10.15%. Completeness students in realistic mathematics learning on the material arithmetic operations of addition and subtraction of integers for fourth grade students of SDN Jenangan, Kwadungan, Ngawi gained mastery learning students individually sebannyak 12 students from the number of students as many as 15 students altogether, which is not completed individually as 3 students. While the classical completeness, acquired 80% of students who completed study.</p><p> </p><p> </p>
EFEKTIFITAS PEMBELAJARAN KOOPERATIF TIPE NHT DENGAN PENDEKATAN KONTEKSTUAL PADA PEMBELAJARAN BANGUN RUANG SISI DATAR
Authors: Pradana Lingga Nico 
Published: July 2017

<p>The purpose of this research was to determine the effect of learning models to student achievement. Learning models compared between NHT-CTL, NHT and direct instruction. Method of research used quasi experimental with the factorial design of 3x1. Population of this research was all students class VIII in SMP Negeri at Madiun City. The sampling technique using a stratified cluster random sampling. Samples in this research were 266 students with 91 students as experimental class I, 88 students as experimental class II and 87 students as control class. Data collection methods used documentation and test.Hypothesis testing was performed using one-way analysis of variance with unequal cells. Based on the results of hypothesis testwere concluded that NHT-CTL learning model gave better achievement than NHT learning model and direct instruction, while NHT learning model and direct instruction gave the same achievement. </p>
DEVELOPMENT OF SOCIAL SKILL SCALE FOR EARLY CHILDHOOD
Authors: Budyartati Sri 
Published: July 2017

<p>Many social skills may be learned implicitly, all children can benefit from being taught social skills explicitly, not only children who are developmentally lagging behind their peers. Social skills are not always learned easily. Some children may require repeated instruction and reinforcement of learning. It is also possible for children to have well -developed social skills in one area but not in another. The primary objective of the Social Skill Scale (SSS) is to describe the child's behavior for purposes of socialization and education, rather than diagnosis. It focuses on the child's adaptation to and functioning within his or her environment which is particularly relevant to teachers. The SSS helps teachers design classroom interventions that address both the child's strengths and weaknesses. It includes 115 items that can be completed in just 15 minutes by Early Childhood, a preschool, or Kindergarten teacher. These items cover Three basic scales and ten components or summary scales</p><p> </p>
IMPLEMENTATION OF INDONESIAN LEARNING STORY SKILL OF CARTOON PUPPET MEDIA OF STUDENT OF GRADE IV OF STATE PRIMARY SCHOOL
Authors: Rulviana Vivi 
Published: July 2017

<p align="center"> </p><p>The objective of this research is to investigate the planning and implementation telling skill the use of cartoon puppet media of the student in Grade IV of State Primary School of Tladan 2, Kawedanan, Magetan.This research used the qualitative research method. The source of this research were Principal, Class Teacher of Grade IV, and the students in Grade IV by using interview, and observation. They were analyzed by using the interactive model of analysis comprising data reduction, data display, and conclusion drawing of verification.The results of research are as follows: 1) the planning of telling by teacher with preparing the annual program, the semester program, the details of effective weeks, the journal of teaching, lesson plan, syllabus development and the development of assessment systems, 2) Implementation of the learning skills of telling is packed with a variety of methods and media puppet cartoon. Teachers began teaching with fun activities for the creation of learning readiness, motivation and interest in learning in students. Teachers utilized cartoon puppet media in learning storytelling in the fourth grade to get a great result for students for example: interested in learning, motivation, self-confidence and have the ability to tell a coherent accordance with the storyline.</p><p> </p>
PENGEMBANGAN MULTIMEDIA PEMBELAJARAN DALAM MENINGKATKAN EFEKTIVITAS PEMBELAJARAN PADA MATA KULIAH KOMPUTER DAN MEDIA PEMBELAJARAN PRODI PGSD IKIP PGRI MADIUN
Authors: Anggrasari Liya Atika 
Published: July 2017

<p align="center"> </p><p>Research and development is intended to produce multimedia learning course on Computer and Media Education for students of primary school teaching as a viable learning medium. The research was conducted with the adaptation of the model development research Borg &amp; Gall. These stages are the preliminary study stage include library research and field study. Product development phase include planning, design learning, producing multimedia and expert validation. Pilot phase trial products include a one-one, small group and large group. Subject trial Prodi PGSD fourth semester student. Data were collected through questionnaires and observations, the results were analyzed by quantitative descriptive analysis. The results showed that: (1) multimedia learning has been generated through five stages of development; (2) the feasibility aspects of learning, content, appearance and technical learning multimedia product is included in both categories with a score of 4.08 in a row; 4.32; 4.00; and 4.07; and (3) learning multimedia product can improve the effectiveness of learning computer courses and learning media. These results make it worth the learning multimedia learning courses as a source of Computer and Media Education for Teachers' Training College students Prodi PGSD PGRI Madiun.</p>
LESSON STUDY PENGEMBANGAN BAHAN PEMBELAJARAN BERBASIS POTENSI LOKAL UNTUK MENINGKATKAN KOMPETENSI PROFESIONAL GURU SD DI KABUPATEN KEBUMEN
Authors: Rokhmaniyah Rokhmaniyah , Surandari Kartika Christy 
Published: July 2017

<p>This study aims to: (1) apply lesson study in the development of learning materials based on local potential to improve the professional competence of primary school teachers in Kebumen in 2016; (2) produce learning materials based on local potential through lesson study as an effort to improve the professional competence of elementary school teachers in Kebumen in 2016. This study overall approach development (Research and Development / R &amp; D). These research subjects were elementary school teachers in Kebumen numbered 50 people. Selection of study subjects according to the school characteristics, was by observing the accreditation status of the school and teacher status. The collection of data were through (1) Focus Group Discussion (FGD). (2) observation, (3) test, (4) study the documentation, (5) interview, (6) checklish behavior, and (7) video. It can be concluded: (1) Lesson study based on learning materials development of local potential improve the professional competence of elementary school teachers in Kebumen 2015. (2) Lesson study can produce learning materials based on local potential quality. Improving the quality of the results of the implementation of lesson study the development of learning materials based on local potential to improve the professional competence of elementary school teachers in Kebumen 2015 reached 90%.</p><strong>Keywords</strong>: professional competence, lesson study, the local potential.