bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frequent drinking of small volumes improves cardiac function and survival in rats with chronic heart failure
Authors: Zheng Can , Li Meihua , Kawada Toru , Inagaki Masashi , Uemura Kazunori , Sugimachi Masaru 
Published: November 2017

AbstractFluid retention is the main reason for the high hospitalization rate among patients with chronic heart failure (CHF). Given the lack of knowledge about fluid intake regulation and its consequences in patients with CHF, current guidelines do not provide clear direction for fluid management. Using a rat model of CHF, we investigated altering drinking behaviors and explored fluid management strategies. CHF was induced by ligating the left anterior descending coronary arteries in 8‐week‐old, male, Sprague‐Dawley rats. A custom‐designed drop counting and feedback control system was used to record and modulate drinking behaviors. During the first month after an induced myocardial infarction (MI), we observed that the spontaneous per drinking volume (PDV) was significantly increased in animals with prolonged intervals between drinking episodes. In addition, there was a significant inverse correlation between the early PDV and the post‐MI lifespan (r = −0.907; P < 0.001). Moreover, modulating the drinking behavior of rats with CHF to involve frequent drinking of small PDVs significantly enhanced hemodynamics and prevented cardiac remodeling, with a significant improvement in the 180‐day survival rate, compared with animals allowed to drink freely (50% vs. 36%; P < 0.01). The results of dynamic PDV changes, after MI, suggest that an impaired thirst mechanism is associated with the sensing and regulating of fluid balance in rats with CHF. These results suggest that increasing the drinking frequency, with small PDVs, may be beneficial to preventing progression of cardiac dysfunction in CHF.
Match Load of Soccer Players in Defensive Formation and Its Impact on the Level of Speed Abilities
Authors: Holienka Miroslav , Horný Michal 
Published: November 2017

Abstract
The aim of this study was to investigate the impact of the match load in soccer on the level of the selected speed abilities in the playing positions of the outside defender and central defender. Speed abilities in all their demonstrations are one of the most important fitness skills in today’s soccer. In our research, we assumed that the higher the match load players achieve, the greater the impact of this load on the level of the selected speed abilities would be. We carried out a cross-sectional ex post facto research. The monitored group consisted of the players of the team playing in the first league (Fortuna League). Their average age was 22.9 ± 4.5 years. We conducted the measurements in the preparation periods during pre-season matches. We carried out a total of 63 individual measurements. We measured the level of the match load and the performance in 10, 20 and 30 meter runs from a standing start before the match and after the match. Except of outside defenders in 30-meter run (W = 12; p = 0.02) we did not confirm a significant impact of the match load on the level of the selected speed (acceleration) abilities. Its effect size reached from d = 0.1 to d = 0.6. In addition, the correlations between match load and performance changes in all three tests were nonsignificant (p ≥ 0.5). Only 0.2 to 8.5 % of the variability in speed tests was shared with the level of match load.
Application of Two Intervention Programs in Order to Optimize Motivation and to Improve Eating Habits in Adult and Elderly Women
Authors: Leyton Marta , Batista Marco , Lobato Susana , Aspano Mª Isabel , Jiménez Ruth 
Published: November 2017

Abstract
The objective of this study was to analyse the effectiveness of two intervention programs: a physical exercise program with strategies to support the three basic psychological needs (autonomy, competence and relatedness); and a physical exercise program with nutritional education in order to improve the lifestyles of adult and elderly women who practiced functional maintenance. The Self-Determination Theory was applied as the theoretical framework. A sample of 135 women aged between 40 and 88 years (59.66 ± 10.76) who enrolled in a 12-week functional maintenance program and attended 24 exercise classes took part in the study. A quasi-experimental study was performed where strategies to support the three basic psychological needs were applied to one group and strategies for the improvement of eating habits were applied to the other group. No strategy was applied to the control group. The main results showed an improvement in experimental groups I and II when compared to the control group regarding the variables of autonomy, competence, intrinsic regulation, identified regulation, introjected regulation, external regulation and eating habits, after the application of the intervention programs. The conclusion is that both intervention programs were successful with this project’s participants and that it is crucial to promote such intervention programs in functional maintenance classes, as they foster healthy lifestyles among participants.
Hardware/software trade-offs for shared resources virtualization in mixed-criticality automotive multicore systems
Authors: Sandmann Timo , Richter Andre , Heyszl Johann , Lübbers Enno 
Published: November 2017

Abstract
Virtualization plays an important role for embedded systems where
hardware support can prove beneficial, but these systems also pose
a challenge due to power, resource constraints; reliability, safety,
real-time requirements; diversity of devices, and operating
systems. Therefore a trade-off between flexibility, determinism and
performance exists in the embedded application domain. As
virtualization in software always incurs overhead due to context
switching, interrupt handling, etc. the aim is to minimize the
overhead and make execution more deterministic using hardware
support.
Online monitoring for safety-critical multicore systems
Authors: Tobuschat Sebastian , Kostrzewa Adam , Bapp Falco K. , Dropmann Christoph 
Published: November 2017

Abstract
Using multicore processors in safety-critical systems is a challenge as well as an opportunity. The real parallelism,
which may affect synchronization and determinism, leads to a safety-challenge, because new possible interferences might
arise. Additionally, redundant software execution is possible within multicore systems. In complex multicore architectures
one of the most important challenges is to know the system behavior and the recognition of any variations from the normal
system behavior has to be guaranteed. For those cases it is necessary to monitor several states of the system,
configurations, timing, etc. To monitor such a complex system a lot of information from the inside of the system needs to
be evaluated without affecting the rest of the MPSoC.
Treating Wrongs as Wrongs: An Expressive Argument for Tort Law
Authors: Hershovitz Scott 
Published: November 2017

AbstractThe idea that criminal punishment carries a message of condemnation is as commonplace as could be. Indeed, many think that condemnation is the mark of punishment, distinguishing it from other sorts of penalties or burdens. But for all that torts and crimes share in common, nearly no one thinks that tort has similar expressive aims. And that is unfortunate, as the truth is that tort is very much an expressive institution, with messages to send that are different, but no less important, than those conveyed by the criminal law. In this essay, I argue that tort liability expresses the judgment that the defendant wronged the plaintiff. And I explain why it is important to have an institution that expresses that judgment. I argue that we need ways of treating wrongs as wrongs, so that we can vindicate the social standing of victims. Along the way, I consider the continuity between tort and revenge, and I suggest a new way of thinking about corrective justice and the role that tort plays in dispensing it. I conclude by sketching an agenda for tort reform that would improve tort’s ability to serve its expressive function.
Protein Moonlighting Revealed by Noncatalytic Phenotypes of Yeast Enzymes
Authors: Espinosa-Cantú Adriana , Ascencio Diana , Herrera-Basurto Selene , Xu Jiewei , Roguev Assen , Krogan Nevan J , DeLuna Alexander 
Published: November 2017

AbstractAn increasing number of multifunctional proteins are being identified, but it is still unclear to what extent proteins moonlight beyond their annotated...A single gene can partake in several biological processes, and therefore gene deletions can lead to different—sometimes unexpected—phenotypes. However, it is not always clear whether such pleiotropy reflects the loss of a unique molecular activity involved in different processes or the loss of a multifunctional protein. Here, using Saccharomyces cerevisiae metabolism as a model, we systematically test the null hypothesis that enzyme phenotypes depend on a single annotated molecular function, namely their catalysis. We screened a set of carefully selected genes by quantifying the contribution of catalysis to gene deletion phenotypes under different environmental conditions. While most phenotypes were explained by loss of catalysis, slow growth was readily rescued by a catalytically inactive protein in about one-third of the enzymes tested. Such noncatalytic phenotypes were frequent in the Alt1 and Bat2 transaminases and in the isoleucine/valine biosynthetic enzymes Ilv1 and Ilv2, suggesting novel “moonlighting” activities in these proteins. Furthermore, differential genetic interaction profiles of gene deletion and catalytic mutants indicated that ILV1 is functionally associated with regulatory processes, specifically to chromatin modification. Our systematic study shows that gene loss phenotypes and their genetic interactions are frequently not driven by the loss of an annotated catalytic function, underscoring the moonlighting nature of cellular metabolism.
Effectiveness of a Kindergarten-Based Intervention for Preventing Childhood Obesity
Authors: Hu Yan , He Jian-Rong , Liu Fang-Hua , Li Wei-Dong , Lu Jin-Hua , Xing Yan-Fei , Lin Sui-Fang , Liu Xian , Bartington Suzanne , Feng Qiong , Xia Hui-Min , Lam Kin Bong Hubert , Cheng Kar Keung , Qiu Xiu 
Published: November 2017

BACKGROUND AND OBJECTIVES:Interventions to prevent childhood obesity targeting school age children have mostly reported limited effectiveness, suggesting such prevention programs may need to start at an earlier age, but evidence has been scarce. We reported a pilot study aiming to demonstrate the feasibility of a multifaceted intervention for preschool children and to provide a preliminary assessment of the effectiveness.METHODS:This nonrandomized controlled trial recruited children aged 3 to 6 years from 6 kindergartens in Guangzhou, China. Based on the preference of the School and Parents Committees, 4 kindergartens (648 children) received a 3-component intervention (training of kindergarten staff, initiating healthy curriculum for children, and close collaboration between families and kindergartens) over 12 months, while the other 2 kindergartens (336 children), serving as controls, received routine health care provision. Outcome measures were the changes in BMI z score between baseline and the end of 12 months, and the prevalence of postintervention children who were overweight or obese.RESULTS:By 12 months, children within the intervention group had a smaller BMI z score increase (0.24) compared to the control (0.41), with a difference of –0.31 (95% CI –0.47 to –0.15). The prevalence of overweight or obesity was also lower among the intervention group at the end of the study (OR: 0.43, 95% CI 0.19 to 0.96), adjusted for baseline status.CONCLUSIONS:Our results indicated a multicomponent health behavior intervention might be effective in reducing the prevalence of obesity, but the longer term effects will need confirmation from randomized controlled trials.
Ecological responsibility of Benedictine monasteries: a study of three cases (Plankstetten, Andechs and Gut Aich)
Authors: Sawicki Bernard 
Published: November 2017

This paper presents the practical contribution of three Benedictine monasteries to an integrated ecology, strongly recommended in pope Francis’ encyclical Laudato si’. Based mainly on the materials inserted on the websites of these monasteries, a particular and important connection is observed between modern, ecological solutions and pastoral activities. Everything arises from the balanced Benedictine spirituality, where liturgy and communal life are integrated through personal prayer and reading of the Bible. After considering the motivations presented by these three monasteries for their ecological accomplishments, the specific domains are examined, such as self-sufficiency, energy and gardens.
Siostra Klara Staszczak (1905–1991) jako przykład heroicznej realizacji konsekracji zakonnej
Authors: Michalak Mariola Małgorzata M. 
Published: November 2017

Klementyna Staszczak – s. Maria Klara urodziła się 6 listopada 1905 roku w Żdżarach w powiecie włodzimierskim. W 1922 roku wstąpiła do Zgromadzenia Sióstr Benedyktynek Misjonarek. Pierwsze śluby zakonne złożyła 15 sierpnia 1924 roku w Kowlu, śluby wieczyste – 15 sierpnia 1931 roku w Łucku. Na Ukrainie przebywała w latach 1924–1943; 1971–1986; 1989–1991. Siostra Klara Staszczak szczególnie umiłowała Kresy Wschodnie, którym oddała całe swe serce. Heroizm realizacji konsekracji zakonnej s. Klary ukształtowała wiara, przeżywana w codziennej modlitwie oraz podejmowanym trudzie kroczenia drogą przykazań i Ewangelii. Heroiczne wręcz pokonywanie trudności na drodze odnawiającego się zgromadzenia na Kresach Wschodnich pokazuje silne zjednoczenie s. Klary z Chrystusem. Dzięki całkowitemu oddaniu siebie Jezusowi jako Panu i Zbawicielowi oraz rzetelnej pracy w duchu Reguły św. Benedykta, s. Klarze udało się na nowo zaszczepić i rozwinąć działalność Zgromadzenia Sióstr Benedyktynek Misjonarek na Ukrainie. Całe jej życie było służbą Bogu, Kościołowi, zgromadzeniu i drugiemu człowiekowi, szczególnie temu najbardziej potrzebującemu ewangelicznej troski. Zmarła 19 czerwca 1991 roku w Barze na Podolu, tam też została pochowana. Do dnia dzisiejszego siostry na Ukrainie kontynuują spuściznę duchową matki założycielki, którą s. Klara po 60 latach nieobecności sióstr na Kresach Wschodnich zaszczepiła na nowo na tej ziemi.
Prasa katolicka a polityka. Casus ks. Zygmunta Kaczyńskiego
Authors: Szczepaniak Maciej 
Published: November 2017

W historii polskich mediów katolickich niemałą rolę odegrała Katolicka Agencja Prasowa (KAP) działająca w latach 1927–1939. Autor artykułu prezentuje polityczny kontekst działalności publicystycznej KAP pod kierownictwem ks. Zygmunta Kaczyńskiego w świetle materiału badawczego zgromadzonego w archiwach watykańskich. Casus ks. Kaczyńskiego wydaje się dobrym punktem wyjścia do dalszej refleksji nad złożonym problemem relacji poglądów politycznych redaktora naczelnego do potrzeby zrównoważonego opisu rzeczywistości. Działalność prasowa domagała się od agencji poruszania tematów o charakterze społecznym i politycznym, ale wyraźnie deklarowane poglądy polityczne jej dyrektora odczytywane były jako wspieranie jednej partii i krytykowanie obozu rządowego. Jak wynika z przytoczonych materiałów źródłowych, nawet w łonie episkopatu nie było jednoznacznej opinii na temat ks. Kaczyńskiego, czego wyrazem są skrajne stanowiska kard. Augusta Hlonda i kard. Aleksandra Kakowskiego.
The reliability of fine needle aspiration cytology in the diagnosis of thyroid swelling
Authors: Syed Obaid , Auti Anand 
Published: November 2017

Background: For a thyroid swelling, FNAC is the primary investigation. In most of the lesions, after excision, the Histopathology remains the same, but at times a few surprises do occur when FNAC reported benign lesions are found to be malignant on histopathology. The study aims to find reliability of FNAC in diagnosing Thyroid Lesions.Methods: This prospective study was conducted on 111 patients with thyroid swelling attending IIMSR, Medical College, Jalna during a period of two years. These patients with thyroid lesions were subjected to FNAC and then following the surgery correlated with the histopathology report.Results: Majority of the patients were in the age group of 30-50 years with female predominance. Out of 111 patients studied with FNAC, 1 sample was inadequate. Among remaining 110 cases 99 were benign thyroid lesions, 6 were malignant and 5 were highly suspicious of malignancy. HPE of thyroid specimen confirmed 101 cases as benign and 9 cases as malignant. Case in which inadequate material was obtained on FNAC was not included in study.Conclusions: FNAC is about 98.18 % reliable in diagnosing thyroid lesions. FNAC is easy, reliable and accurate investigation for all thyroid swellings.
A comparative study between light and heavy polypropylene mesh in lichtenstein repair of inguinal hernia
Authors: Nasiruddin Syed , Suresh Sridhar , H. Jayanth D. 
Published: November 2017

Background: Inguinal hernia repair is one of the most common surgical procedures performed in practice. Although numerous techniques have been described, currently tension free mesh repair is the standard of care in the treatment of hernias because of the low recurrence rates.Methods: A comparative study between Light and Heavy Polypropylene mesh in Lichtenstein repair of inguinal hernia was conducted at Department of General Surgery in MVJ Medical college and Research Hospital, Hoskote, Bangalore on patients admitted in Department of General Surgery between November 2014 to July 2016 undergoing Lichtenstein tension free mesh repair for inguinal hernia. The study is a prospective study. 30 Patients were in Light mesh group and 30 were in Heavy mesh group.Results: Age group of 31-40 yrs had highest incidence of inguinal hernia. Males outnumber Females in incidence of Inguinal Hernia. Foreign body sensation in Heavy mesh group is significantly high. Average of 26.7% of the patients had foreign body sensation in Heavy mesh group. Whereas in Light group average was 10%. Chronic pain also showed significant readings in Heavy mesh group. Stiffness over abdominal wall was complained by 10% of patients overall in the light mesh group whereas no patients had this complaint in light mesh group. Recurrence was high in light mesh group where total of 5 patients had recurrence and in heavy there were only 2 patients with recurrence.Conclusions: In my study light mesh has been proved to be better than heavy mesh in treatment of inguinal hernia.
Distal Biceps Tendon Anatomic Repair
Authors: Schmidt Christopher C. , Styron Joseph F. , Lin Edward A. , Brown Brandon T. 
Published: November 2017

Distal biceps injuries, which usually occur in active middle-aged men, can result in chronic pain and loss of supination and flexion strength
3
,
4
. Surgical repair of a ruptured distal biceps tendon can reliably decrease pain and improve strength compared with nonoperative management
3
,
4
. However, even following successful healing and rehabilitation of a surgically repaired biceps tendon, full supination strength is rarely restored
5
-
7
. The expected outcome following distal biceps repair using a traditional anterior approach is a measurable loss of rotational strength, especially from neutral to supinated positions
5
,
7
. This deficit can lead to difficulty with occupational and recreational activities
5
,
8
.
The center of an uninjured biceps tendon inserts into the radial tuberosity 6.7 mm anterior to its apex
9
,
10
. This posterior location forces the biceps tendon to wrap around the radial protuberance during pronation, thus utilizing the protuberance as a mechanical cam during forceful forearm supination
10
,
11
. The distal biceps tendon comprises a medial short head and lateral long head; the 2 heads are continuations of the proximal muscles
2
,
20
,
21
. The short head inserts distal to the long head on their radial attachment site
2
,
20
,
21
. Performing a distal biceps repair via an anterior approach typically places the center of the reattachment site 12.9 mm anterior to its apex or approximately 6 mm anterior to an uninjured control tendon
9
. This shifts the repair site from its anatomic location (posterior to the radial protuberance) to a new nonanatomic location (on top of the protuberance). This anterior reattachment location decreases the cam effect of the radial protuberance, resulting in an average supination loss of 10% in neutral rotation and 33% in 60° of supination
7
,
10
.
A posterior approach to the radial tuberosity using 2 separate intramedullary buttons for the short and long heads reliably positions the distal biceps insertion at its anatomic footprint, which is posterior to the radial protuberance
9
,
10
,
11
. This technique has been named the distal biceps tendon anatomic repair. Not only does it restore the normal supination cam effect of the radial protuberance, but it also provides superior initial fixation strength, with load to failure strength similar to the native tendon
1
.
The distal biceps anatomic repair can be divided into the following 9 key steps: Step 1: Preoperative planning; Step 2: Positioning; Step 3: Identifying and retrieving the tendon; Step 4: Preparing the 2 heads of the tendon; Step 5: Posterior exposure of tendon footprint; Step 6: Drilling the short and long-head drill holes; Step 7: Passage of the tendon; Step 8: Unicortical button fixation; Step 9: Alternative fixation: cortical trough; and Step 10: Postoperative management.
Management of Microbiologically Influenced Corrosion in Risk-Based Inspection Analysis
Authors: Skovhus Torben Lund , Andersen Erlend Stokstad , Hillier Elizabeth 
Published: November 2017

Summary
Operating offshore oil and gas production facilities is often associated with high risk. To manage the risk, operators commonly use aids to support decision making in the establishment of a maintenance and inspection strategy. Risk-based inspection (RBI) analysis is widely used in the offshore industry as a means to justify the inspection strategy adopted.
The RBI analysis is a decision-making technique that enables asset managers to identify the risk related to failure of their most critical systems and components, with an effect on safety, environmental, and business-related issues. Risk is a measure of possible loss or injury, and is expressed as the combination of the incident probability and its consequences. A component may have several associated risk levels, depending on the different consequences of failure and the different probabilities of those failures occurring.
Microbiologically influenced corrosion (MIC) is a degradation mechanism that has received increased attention from corrosion engineers and asset operators in the past decades. In this paper, the most recent models that have been developed to assess the impact of MIC on asset integrity will be presented and discussed.
From a risk perspective, the current models do not satisfactorily assess MIC, and the models lack a proper view of the MIC threat. Therefore, a review of known parameters that affect MIC is presented. The mapping and identification of parameters are based on the review of past models and an extensive up-to-date literature study.
The parameters are discussed and subsequently combined in a novel procedure that allows the assessment of MIC in an RBI analysis. The procedure is subdivided into one screening step and a detailed assessment, which fits the recommended approach to assess risk in an RBI analysis. To illustrate the practical application of the developed procedure, a field case is presented.