bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fatty acid composition MRI of epicardial adipose tissue: Methods and detection of proinflammatory biomarkers in ST‐segment elevation myocardial infarction patients
Authors: Echols John T. , Wang Shuo , Patel Amit R. , Hogwood Austin C. , Abbate Antonio , Epstein Frederick H. 
Published: September 2024

AbstractPurposeTo develop a method for quantifying the fatty acid composition (FAC) of human epicardial adipose tissue (EAT) using accelerated MRI and identify its potential for detecting proinflammatory biomarkers in patients with ST‐segment elevation myocardial infarction (STEMI).MethodsA multi‐echo radial gradient‐echo sequence was developed for accelerated imaging during a breath hold using a locally low‐rank denoising technique to reconstruct undersampled images. FAC mapping was achieved by fitting the multi‐echo images to a multi‐resonance complex signal model based on triglyceride characterization. Validation of the method was assessed using a phantom comprised of multiple oils. In vivo imaging was performed in STEMI patients (n = 21; 14 males/seven females). FAC was quantified in EAT, subcutaneous AT, and abdominal visceral AT.ResultsPhantom validation demonstrated strong correlations (r > 0.97) and statistical significance (p < 0.0001) between measured and reference proton density fat fraction and FAC values. In vivo imaging of STEMI patients revealed a distinct EAT FAC profile compared to subcutaneous AT and abdominal visceral AT. EAT FAC parameters had significant correlations with left ventricular (LV) end‐diastolic volume index (p < 0.05), LV end‐systolic volume index (p < 0.05), and LV mass index (p < 0.05).ConclusionsAccelerated MRI enabled accurate quantification of human EAT FAC. The relationships between the EAT FAC profile and LV structure and function in STEMI patients suggest the potential of EAT FAC MRI as a biomarker for adipose tissue quality and inflammatory status in cardiovascular disease.
Investigating microstructural changes between in vivo and perfused ex vivo marmoset brains using oscillating gradient and b‐tensor encoded diffusion MRI at 9.4 T
Authors: Santini Tales , Shim Alyson , Liou Jr‐Jiun , Rahman Naila , Varela‐Mattatall Gabriel , Budde Matthew D. , Inoue Wataru , Everling Stefan , Baron Corey A. 
Published: September 2024

AbstractPurposeTo investigate microstructural alterations induced by perfusion fixation in brain tissues using advanced diffusion MRI techniques and estimate their potential impact on the application of ex vivo models to in vivo microstructure.MethodsWe used oscillating gradient spin echo (OGSE) and b‐tensor encoding diffusion MRI to examine in vivo and ex vivo microstructural differences in the marmoset brain. OGSE was used to shorten effective diffusion times, whereas b‐tensor encoding allowed for the differentiation of isotropic and anisotropic kurtosis. Additionally, we performed Monte Carlo simulations to estimate the potential microstructural changes in the tissues.ResultsWe report large changes (˜50%–60%) in kurtosis frequency dispersion (OGSE) and in both anisotropic and isotropic kurtosis (b‐tensor encoding) after perfusion fixation. Structural MRI showed an average volume reduction of about 10%. Monte Carlo simulations indicated that these alterations could likely be attributed to extracellular fluid loss possibly combined with axon beading and increased dot compartment signal fraction. Little evidence was observed for reductions in axonal caliber.ConclusionOur findings shed light on advanced MRI parameter changes that are induced by perfusion fixation and potential microstructural sources for these changes. This work also suggests that caution should be exercised when applying ex vivo models to infer in vivo tissue microstructure, as significant differences may arise.
A Novel Prediction Model for Debris Flow Mean Velocity Based on Small Sample Data Taking Jiangjia Gully Watershed as an Example
Authors: Kuang He Wei , Ai Zhi Yong , Gu Gan Lin 
Published: September 2024

ABSTRACTAmong all the factors affecting the destructiveness of debris flow, the mean velocity is one of the most important characteristics. In this paper, we aim to apply a particle swarm optimization (PSO) based on the relevance vector machine (RVM) to predict the mean velocity. The PSO is used to optimize kernel parameters inside the RVM, whereas the RVM is responsible for completing the prediction task. Through sample training, a nonlinear relationship can be obtained, enabling a rapid prediction of the mean velocity for new samples. The debris flow dataset of Jiangjia Gully is used to evaluate the performance of PSO‐RVM in this study. Besides, we further compare the prediction results of PSO‐RVM with other prominent approaches, for example, the support vector machine (SVM), BP neural network (BP), and the RVM. The results show that the mean relative error (MRE) of PSO‐RVM is only 0.69%. In addition, BP yields the highest MRE (27.61%), and the MRE (2.75%) corresponding to the RVM is lower than that (5.98%) yielded by the SVM. For the root mean square error (RMSE) and Theil's inequality coefficient (TIC), the PSO‐RVM method still generates much lower RMSE (6.48%) and TIC (0.179%) values than the other three methods. Overall, compared with current debris flow prediction models, the PSO‐RVM achieves high prediction accuracy, fewer optimization parameters, and low computational complexity. Finally, a sensitivity analysis is conducted to explore the dominative factors of debris flow.
Risk perception and quality of working life of nurses in infectious disease department in China: The chain‐mediating effects of psychological resilience and social support
Authors: Zhang Hong‐li , Wu Chao , Hu Meng‐yi , Ma Wen‐jing , Xu Xiao‐ling , Shi Rui‐jie , Lang Hong‐juan 
Published: September 2024

AbstractAimTo determine whether social support and psychological resiliency are significant mediators of the associations between risk perception and quality of working life in Chinese nurses working with infectious diseases.DesignA cross‐sectional study.MethodsA cross‐sectional survey of 879 nurses in infectious diseases department of specialty or general hospitals in China completed online questionnaires on the nurses' risk perception questionnaire, quality of working life, psychological resilience and the social support rating scale.ResultsOur study observed that risk perception directly negatively influences the quality of working life of infectious disease nurses, while psychological resilience and social support positively chain mediate this relationship.ConclusionCritical elements impacting the quality of working life of infectious disease nurses are risk perception, psychological resilience and social support. Managers may think about decreasing the level of risk perception and enhancing the quality of working life of infectious disease nurses by enhancing their psychological resilience and providing support.Public ContributionThe quality of working life of infectious disease nurses should be a priority for nursing management; it is critical to maintain their health and well‐being, raise the quality of care and lower turnover. Managers should create resilience‐building programmes and support tools to assist nurses properly perceive risks and adopt protective strategies to deal with them to improve the quality of working life for nurses.
Going Beyond Philanthropy: A Dual Process Approach to Examine How Consumers Punish Brand Misanthropy
Authors: Tripathy Avilasha , Lyngdoh Teidorlang , El‐Manstrly Dahlia , Antil Anjuman 
Published: September 2024

ABSTRACTMisanthropy, the opposite of philanthropy, represents brand wrongdoings that harm humanity and can be more widespread. Consumer awareness of brand misanthropy and subsequent retaliation against brands are on the rise and pose a more significant managerial challenge than ever before. Despite its growing importance, few studies have explored the connection between consumer's moral decision‐making in the event of brand misanthropy and subsequent avoidance behaviour. Using dual process theory, we expand the rationalist perspective within the field of moral decision‐making by considering the distinct mechanisms through which moral judgment influences consumer brand avoidance behaviour. Using a scenario‐based experiment paired with a survey, our findings suggest that moral judgments positively influence brand avoidance when exposed to brand misanthropy. We also found that moral obligation mediates between moral judgment and brand avoidance. Furthermore, our findings demonstrate that self‐esteem attenuates peoples' propensity to avoid brands. Managerially, our research offers fresh insights and guidance for recognizing and recommending solutions to reduce anti‐brand behaviours in the event of brand misanthropy.
Comparative Governance Quality's Impact on Monetary Policy, Saving, and Economic Growth Dynamics: Empirical Evidence From Nigeria, Egypt and South Africa
Authors: Sule Abubakar , Mohammed Ibrahim Danlami , Umaru Ojonimi , Gana Jonah Abacoso 
Published: September 2024

ABSTRACTOur study examines the comparative impact of governance quality on the dynamic relationship between monetary policy rate, saving, and economic growth in emerging economies in sub‐Saharan African countries from 2005Q1 to 2022Q4. Using the Toda‐Yamamoto (TY) model, we found that governance quality influence on monetary policy rate is negative with adverse effect on investment‐growth while exerting positive influence on savings‐growth nexus in Nigeria but the contribution is quite appreciative and can be leverage on. Governance quality exert negative influence on monetary policy rate but with positive direction from investment and savings to growth in Egypt. The magnitude of the monetary policy rate, savings, investment is quite negligible in Egypt. For South Africa, governance quality exerts positive influence on monetary policy rate but failed to translate to positive effect on investment, savings to growth in South Africa. Although, the contribution of monetary policy rate, savings, investment to growth is significant in South Africa. Thus, enhancing institutional development to foster a more effective financial incentive system and seamless policy transmission is crucial to address the impact of governance quality on monetary policy outcomes and enable better macroeconomic interactions.
Leveraging long‐lasting insecticide‐incorporated netting to improve fumigation efficacy against stored product insects
Authors: Ranabhat Sabita , Brabec Daniel , Lillich Madison , Scheff Deanna S. , Zhu Kun Yan , Bingham Georgina V. , Morrison William R. 
Published: September 2024

AbstractBACKGROUNDLong‐lasting insecticide‐incorporated netting (LLIN) has successfully been used to impair mobility and prevent infestation of stored grain by stored product beetles. Understanding how to integrate LLIN with existing integrated pest management (IPM) tactics, such as phosphine fumigation, can further enhance IPM programs.RESULTSWe used three 110 metric tons (MT) capacity grain bins, and in each, 60 perforated buckets (e.g., miniature silos) were filled with 500 g of uninfested wheat. Miniature silos were protected by LLIN (0.3% α‐cypermethrin, Carifend®, BASF), positive control (without insecticide), or negative control (no netting). Half of each treatment was randomly assigned to phosphine fumigation treatment, while the remainder were not fumigated. Monthly samples of 100 g of grain from four silos from each treatment in four blocks from three‐grain bins were taken between June and October both in 2022 and 2023. We determined whether phosphine fumigation could be reduced with the use of LLIN over the season. Overall, we found that silos protected with LLIN showed insect dispersal and progeny production that was reduced by 83–99% and 89–99%, respectively, compared with insecticide‐free netting and no‐netting controls. Additionally, damage in silos was reduced by 37–99% compared with controls. Importantly, the total number of fumigations could be reduced by 68–91% by using LLIN compared with controls.CONCLUSIONOur study demonstrates that LLIN is consistently effective for existing pest management tactics such as phosphine fumigation in bulk storage structures. © 2024 Society of Chemical Industry. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.
Characterization of ATP‐binding cassette transporters associated with emamectin benzoate tolerance: from the model insect Drosophila melanogaster to the agricultural pest Spodoptera frugiperda
Authors: Wang Lixiang , Guo Shaoyi , Wen Bin , Deng Zhongyuan , Ding Qian , Li Xianchun 
Published: September 2024

AbstractBACKGROUNDMultiple families of detoxification genes, including the increasingly recognized family of ATP‐binding cassette (ABC) transporters, work together to influence the toxicity of synthetic insecticides and thus their resistance. Effective management of insecticide resistance requires identification of all toxicity‐affecting members from each family of toxicity‐related genes.RESULTSHere, we used emamectin benzoate (EB), ABC transporters and Spodoptera frugiperda as a working case to test whether the strategy of ‘from the model insect Drosophila melanogaster to agricultural pests’ can identify all or most ABC transporter members related to EB tolerance in S. frugiperda. After confirming the involvement of ABC transporters in the toxicity of EB against fruit fly with the ABC inhibitor verapamil, four ABC transporter genes (DmCG3327, DmCG11147, DmCG4822, and DmCG7627) were found to be involved in EB tolerance using RNA interference‐based family‐wide functional screening. A combination of phylogenic analysis and a reciprocal TBLASTN search identified five S. frugiperda ABC transporter members as homologs (SfABCC4, SfABCG1, and SfABCG23) or one‐way best hits (SfABCG4 and SfABCG20) of the four fly ABC genes. Real‐time quantitative polymerase chain reaction (qPCR) analysis found that all five S. frugiperda ABC transporter genes were inducible by EB, and expressed in all the developmental stages and larval tissues, but with significant quantitative differences among stages and tissues. A cytotoxicity assay of ABC‐overexpressing Sf9 cell lines showed that all the five S. frugiperda ABC transporter genes made Sf9 cells tolerant to EB.CONCLUSIONSThis study not only identifies nine ABC transporter genes related to EB tolerance from D. melanogaster (four genes) and S. frugiperda (five genes), but also demonstrates the utility and effectiveness of the ‘model to pests’ strategy to identify most toxicity‐affecting members from a given family of toxicity‐related genes. © 2024 Society of Chemical Industry.
Computational Approach to the Study of Acidochromic Properties of Donor‐π‐Acceptor Systems Based on Dimethylamino‐Substituted Dyes With Intramolecular Charge Transfer
Authors: Mediantsev Evgeny , Dubinets Nikita , Lobova Natalia 
Published: September 2024

ABSTRACTThis work is devoted to the study of the influence of protonation on the photophysical properties of dimethylamino‐substituted styryl dyes. The formation of a bond on the unshared nitrogen electron pair involved in conjugation with the dye chromophore changes the mobility of the terminal group of the donor fragment and thereby “switches” the molecule from n‐π* to π‐π* mode. The correlations found between changes in the electron density of the dye in native form and during protonation and changes in its properties contribute to the study of the ground and excited states of these compounds and the energy transitions between them. Comparison with analog compounds and consideration of vibronic effects allow us to evaluate the potential advantages and limitations of the TD‐DFT method in the calculation of electronic transitions in styryl dyes. The work contributes to the understanding of the influence of protonation on the behavior of dyes with a nitrogen atom in the donor part of the chromophore of the molecule. The patterns found can be applied to similar chromophore systems.
Factor exposures of environmental, social, and governance (ESG) indexes
Authors: Ascioglu Asli , Saatcioglu Kemal 
Published: September 2024

AbstractWe examine the factor exposures of Environmental, Social, and Governance (ESG) indexes used as benchmarks by the largest ETFs with social responsibility (SR) focus. Our sample includes 31 ESG/SR indexes benchmarked by ESG/SR ETFs with the largest assets under management (AUM) as of January 31, 2020. We pay special attention to quality factors and use robustness of operating profitability and investment characteristics as proxies. Our findings indicate these indexes mostly act as expected in terms of size and value factors. Momentum factor, for the most part, is not significant. About half (14/31) exhibit a statistically significant positive quality tilt. However, there are some statistically significant negative tilts on proxies used for quality that can be explained by index composition. We also attempt to isolate the factor exposures due to the specific characteristics of the ESG indexes by pooling the individual ESG indexes by their segment benchmarks and analyzing ESG index returns in excess of non‐ESG segment benchmark returns. Most exposures stay intact, though some reverse. However, the positive quality tilts persist. As the move from active to passive investment accelerates in the ESG space, understanding the factor exposures of these indexes is essential for investors, financial advisors, and fund managers.
In Situ Bioorthogonal Repair of the Vascular Endothelium Glycocalyx to Treat Acute Lung Injury
Authors: Wang Yao , Qu Rui , Du Wenxuan , Li Wei , Wang Anqi , Chen Zhoujiang , Gao Huile , Wu Di , Geng Fang , Scherman Daniel , Wang Xianwen , Shi Sanjun , Zou Liang , Li Hanmei 
Published: September 2024

AbstractIn acute lung injury, destruction of the lung endothelial glycocalyx leads to vessel permeabilization and contributes to pulmonary edema and inflammation. Heparan sulfate, which accounts for >70% of glycosaminoglycans in the endothelial glycocalyx, plays a crucial physiological anti‐inflammatory role. To treat acute lung injury, it is explored whether a two‐step in vivo bioorthogonal chemistry strategy can covalently link intravenously administered heparan sulfate to the lung vascular endothelium and the damaged glycocalyx. First, fusogenic liposomes (EBP‐Tz‐FLs) carrying the reactive group tetrazine (Tz), and an E‐selectin‐binding peptide (EBP) to target the lung inflammatory endothelium are administered intravenously. This step aimed to anchor the tetrazine group to the membrane of inflammatory endothelial cells. Second, heparan sulfate (HS‐TCO) conjugated to the trans‐cyclooctene (TCO) group, which spontaneously reacts with Tz, is injected intravenously, leading to covalent heparan sulfate addition to the vascular endothelium. In a mouse model of acute lung injury, this approach substantially reduced vascular permeability and attenuated lung tissue infiltration. The EBP‐Tz‐FLs and HS‐TCO showed favorable biocompatibility and safety both in vitro and in vivo. The proposed strategy shows good promise in acute lung injury therapy and covalently anchoring functional molecules onto the membrane of target cells.
On‐Chip Thermoelectric Devices Based on Standard Silicon Processing
Authors: Dimaggio Elisabetta , Masci Antonella , De Seta Amedeo , Salleras Marc , Fonseca Luis , Pennelli Giovanni 
Published: September 2024

AbstractThe strong reduction of thermal conductivity with respect to bulk silicon makes nanostructured silicon one of the best materials for highly efficient direct conversion of heat into electrical power and vice‐versa. The widespread technologies for the integration of silicon devices can be used to define on‐chip micro thermoelectric generators (scavengers); similar structures could also be used for precise and well‐localized cooling through the reverse process of heat pumping. However, the road to the fabrication of integrated thermal energy scavengers or cooler, based on silicon, is still very long. In this work, the design and the fabrication process of on‐chip thermoelectric devices based on a large number of interconnected monocrystalline silicon nanobeams, very tall (>1 µm) and thin (less than 200 nanometers), arranged in large areas combs is shown. The small width of the nanobeams gives a reduced thermal conductivity, and the height perpendicular to the substrate allows the definition of a highly dense collection of nanostructures. The total cross‐section is far broader than that of other nanostructures, a characteristic that guarantees both mechanical stability and larger deliverable power per unit area.
Accelerated Synthesis of TS‐2 Zeolite via 2D Heterogeneous Nucleation for Efficient H2O2 Production
Authors: Liu Xuguang , Huo Kai , Zhuang Junze , Shi Ling , Yao Zhenhua , Hu Maocong , Li Guicun , Liu Wengang , Deng Kangqing 
Published: September 2024

AbstractMEL type c is crucial for addressing energy and environmental crises, yet efficient synthesis remains a challenge due to thermodynamic and kinetic limitations. In this work, TS‐2 as typical zeolite is successfully synthesized with high efficiency (12 h with 92% yield) by introducing titanate acid (TA) 2D nanosheet into a hydrothermal synthesis system. A newly defined TA/TS‐2 heterostructure is precisely identified as being incorporated into the zeolite framework via a heterogeneous nucleation mechanism. Ab initio molecular dynamics simulations deeply revealed the nucleation and growth mechanisms of the TA/TS‐2 heterostructure. The formation energy barrier of Ti─O─Si structural units (88 kJ mol−1) is much lower than that of Si─O─Si units (119 kJ mol−1), leading to more efficient growth of the Ti─O─Si structure. The polarized electronic properties of Ti─O─Si (negative LUMO orbital and larger polarization) further enhanced the reaction probability and stability of Ti─Si bonding. This obtained TA/TS‐2 heterostructure also demonstrated superior activity for photocatalytic production of hydrogen peroxide, which can be attributed to the abundant conductive band holes and narrow bandgap. This research provides an effective strategy for using 2D nanosheets to accelerate zeolite production, as well as an in‐depth molecular‐level insight into the nucleation and growth processes.
Complete CP-eigen bases of meson-baryon chiral lagrangian up to p5-order
Authors: Song Chuan-Qiang , Sun Hao , Yu Jiang-Hao 
Published: September 2024

Abstract
Chiral perturbation theory describes the low energy dynamics of mesons and baryons in terms of the nonlinear Goldstone boson and fermion degrees of freedom. Through the Young tensor technique, we construct the on-shell operator bases for the meson-baryon system up to p5-order, using the chiral dimension power counting and heavy baryon expansion. For the Lorentz structure, additional treatments on off-shell external sources and operators with higher derivatives are necessarily considered, while for the internal structure, the invariant tensor basis is converted into the trace basis equivalently, and Cayley-Hamilton relations are utilized to classify different CP eigen-operators. Finally we present the complete operator set of C+P+, C+P-, C-P+, and C-P- eigen-operators at the p5-order, and obtain the operator counting from the Hilbert series.
Giant graviton expansions and ETW brane
Authors: Hatsuda Yasuyuki , Lin Hai , Okazaki Tadashi 
Published: September 2024

Abstract
We study the giant gravitons in the AdS4 bagpipe geometries involving end-of-the-world (ETW) brane constructed by a single 5-brane and either two stacks or one stack of D3-branes in Type IIB string theory. From the exact formulae and giant graviton expansions of the half-indices for the half-BPS boundary conditions and interfaces in $$ \mathcal{N} $$
N
= 4 super Yang-Mills theory, we obtain the BPS spectra of the fluctuation modes of the AdS4 bagpipe geometries including the ETW brane region.