bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of early cognitive-linguistic treatment for aphasia due to stroke: A randomised controlled trial (Rotterdam Aphasia Therapy Study-3)
Authors: Nouwens Femke , de Lau Lonneke ML , Visch-Brink Evy G , van de Sandt-Koenderman WME (Mieke) , Lingsma Hester F , Goosen Sylvia , Blom Dineke MJ , Koudstaal Peter J , Dippel Diederik WJ 
Published: March 2017

Introduction One third of patients with acute stroke have aphasia. The majority receive speech and language therapy. There is evidence for a beneficial effect of speech and language therapy on restoring communication, but it is unknown whether and how efficacy of speech and language therapy is influenced by timing of treatment. We studied whether speech and language therapy early after stroke by way of intensive cognitive-linguistic treatment is more effective than no speech and language therapy in the Rotterdam Aphasia Therapy Study-3, a multicentre randomised single-blind trial. Methods and patients Stroke patients with first-ever aphasia were randomised within 2 weeks of onset to either 4 weeks of early intensive cognitive-linguistic treatment (1 h/day) or no language treatment. Hereafter, both groups received regular speech and language therapy. Primary outcome was the score on the Amsterdam-Nijmegen Everyday Language Test, measuring everyday verbal communication, 4 weeks after randomisation. Secondary outcomes were Amsterdam-Nijmegen Everyday Language Test at 3 and 6 months. The study was powered to detect a clinically relevant difference of four points on the Amsterdam-Nijmegen Everyday Language Test. Results Of the 152 included patients, 80 patients were allocated to intervention. Median treatment intensity in the intervention-group was 24.5 h. The adjusted difference between groups in mean Amsterdam-Nijmegen Everyday Language Test-scores 4 weeks after randomisation was 0.39, 95% confidence interval: [−2.70 to 3.47], p = 0.805. No statistically significant differences were found at 3 and 6 months after randomisation either. Conclusion Four weeks of intensive cognitive-linguistic treatment initiated within 2 weeks of stroke is not more effective than no language treatment for the recovery of post-stroke aphasia. Our results exclude a clinically relevant effect of very early cognitive-linguistic treatment on everyday language.
Patients with acute stroke are less likely to be admitted directly to a stroke unit when hospital beds are scarce: A Swedish multicenter register study
Authors: Darehed David , Norrving Bo , Stegmayr Birgitta , Zingmark Karin , Blom Mathias C. 
Published: March 2017

Introduction It is well established that managing patients with acute stroke in dedicated stroke units is associated with improved functioning and survival. The objectives of this study are to investigate whether patients with acute stroke are less likely to be directly admitted to a stroke unit from the Emergency Department when hospital beds are scarce and to measure variation across hospitals in terms of this outcome. Patients and methods This register study comprised data on patients with acute stroke admitted to 14 out of 72 Swedish hospitals in 2011–2014. Data from the Swedish stroke register were linked to administrative daily data on hospital bed occupancy (measured at 6 a.m.). Logistic regression analysis was used to analyse the association between bed occupancy and direct stroke unit admission. Results A total of 13,955 hospital admissions were included; 79.6% were directly admitted to a stroke unit from the Emergency Department. Each percentage increase in hospital bed occupancy was associated with a 1.5% decrease in odds of direct admission to a stroke unit (odds ratio = 0.985, 95% confidence interval = 0.978–0.992). The best-performing hospital exhibited an odds ratio of 3.8 (95% confidence interval = 2.6–5.5) for direct admission to a stroke unit versus the reference hospital. Discussion and conclusion We found an association between hospital crowding and reduced quality of care in acute stroke, portrayed by a lower likelihood of patients being directly admitted to a stroke unit from the Emergency Department. The magnitude of the effect varied considerably across hospitals.
Bohseite, ideally Ca4Be4Si9O24(OH4, from the Piława Górna quarry, the Góry Sowie Block, SW Poland
Authors: Szełęg E. , Zuzens B. , Hawthorne F. C. , Pieczka A. , Szuszkiewicz A. , Turniak K. , Nejbert K. , Ilnicki S. S. , Friis H. , Makovicky E. , Weller M. T. , Lemée-Cailleau M.-H. 
Published: March 2017

AbstractBohseite is an orthorhombic calcium beryllium aluminosilicate with variable Al content and an endmember formula Ca4Be4Si9O24(OH4), that was discovered in the Piława Górna quarry in the eastern part of the Góry Sowie Block, ∼50 km southwest of Wrocław, SW Poland. It occurs in a zoned anatectic pegmatite dyke in close association with microcline, Cs-rich beryl, phenakite, helvite, 'lepidolite', probably bertrandite and unidentified Be-containing mica as alteration products after a primary Be mineral, probably beryl. Bohseite forms fan-like or parallel aggregates (up to 0.7 cm) of white, platy crystals (up to 2 mm long) with characteristic striations. It is white with a white streak, is translucent and has a vitreous lustre; it does not fluoresce under ultraviolet light. The cleavage is perfect on {001} and fair on {010}, and neither parting nor twinning was observed. Bohseite is brittle with a splintery fracture and Mohs hardness is 5–6. The calculated density is 2.719 g cm–3. The indices of refraction are α= 1.579, β = 1.580,γ = 1.597, all ±0.002; 2Vobs = 24(3)°, 2Vcalc = 27°; the optic orientation is as follows: X ^a= 16.1°, Y ^b= 16.1°, Z //cBohseite shows orthorhombic diffraction symmetry, space groupCmcm,a= 23.204(6),b= 4.9442(9),c= 19.418(6) Å,V= 2227.7(4) Å3,Z= 4. The crystal structure was refined to anR1value of 2.17% based on single-crystal data, and the chemical composition was determined by electron-microprobe analysis. Bohseite is isostructural with bavenite. Bohseite was originally approved with an end-member composition of Ca4Be3AlSi9O25(OH)3, but subsequent discovery of compositions with Be > 3.0 apfu led to redefinition of its end-member composition, holotype sample and locality, as reported here. There is extensive solid solution in bavenite–bohseite according to the schemeO(2)OH–+T(4)Si4++T(3)Be2+↔O(2)O2–+T(4)Al3++T(3)Si4+, and a general formula for the bavenite–bohseite minerals may be written as Ca4BexSi9Al4–xO28–x(OH)x, where x ranges from 2–4 apfu: Ca4Be2Si9Al2O26(OH)2(bavenite) to Ca4Be4Si9O24(OH)4(bohseite).
Eleonorite, Fe63+(PO4)4O(OH)4·6H2O: validation as a mineral species and new data
Authors: Chukanov Nikita V. , Aksenov Sergey M. , Rastsvetaeva Ramiza K. , Schäfer Christof , Pekov Igor V. , Belakovskiy Dmitriy I. , Scholz Ricardo , de Oliveira Luiz C.A. , Britvin Sergey N. 
Published: March 2017

AbstractEleonorite, ideally Fe63+(PO4)4O(OH)4·6H2O, the analogue of beraunite Fe2+Fe53+(PO4)4O(OH)5·6H2O with Fe2+ completely substituted by Fe3+, has been approved by the International Mineralogical Association Commission on New Minerals, Nomenclature and Classification as a mineral species (IMA 2015-003). The mineral was first described on material from the Eleonore Iron mine, Dünsberg, near Giessen, Hesse, Germany, but during this study further samples were required and a neotype locality is the Rotläufchen mine, Waldgirmes, Wetzlar, Hesse, Germany, where eleonorite is associated with goethite, rockbridgeite, dufrénite, kidwellite, variscite, matulaite, planerite, cacoxenite, strengite and wavellite. Usually eleonorite occurs as red-brown prismatic crystals up to 0.2 mm × 0.5 mm × 3.5 mm in size and in random or radial aggregates up to 5 mm across encrusting cavities in massive 'limonite'. The mineral is brittle. Its Mohs hardness is 3. Dmeas = 2.92(1), Dcalc = 2.931 g cm–3. The IR spectrum is given. Eleonorite is optically biaxial (+), α = 1.765(4), β = 1.780(5), γ = 1.812(6), 2Vmeas = 75(10)°, 2Vcalc = 70°. The chemical composition (electron microprobe data, H2O analysed by chromatography of products of ignition at 1200°C, wt.%) is: Al2O3 1.03, Mn2O3 0.82, Fe2O3 51.34, P2O5 31.06, H2O 16.4, total 99.58. All iron was determined as being trivalent from a Mössbauer analysis. The empirical formula (based on 27 O apfu) is (Fe5.763+Al0.18Mn0.093+)∑6.03(PO4)3.92O(OH)4.34·5.98H2O. The crystal structure (R = 0.0633) is similar to that of beraunite and is based on a heteropolyhedral framework formed by M(1–4)Ø6-octahedra (where M = Fe3+; Ø = O2–, OH– or H2O) and isolated PO4 tetrahedra, with a wide channel occupied by H2O molecules. Eleonorite is monoclinic, space group C2/c, a = 20.679(10), b = 5.148(2), c = 19.223(9) Å, β = 93.574(9)°, V = 2042.5(16) Å3 and Z = 4. The strongest reflections of the powder X-ray diffraction pattern [d, Å (I,%) (Hkl)] are 10.41 (100) (200), 9.67 (38) (002), 7.30 (29) (202̄), 4.816 (31) (111, 004), 3.432 (18) (600, 114, 404, 313), 3.197 (18) (510, 511̄, 006, 314̄, 602), 3.071 (34) (314, 115̄).
Genetic significance of zircon in orthogneisses from Sierra Nevada (Betic Cordillera, Spain)
Authors: Ruiz-Cruz M. D. , de Galdeano C. Sanz 
Published: March 2017

AbstractZircon from two types of orthogneisses (inheritance-rich and inheritance-poor) from Sierra Nevada (Betic Cordillera, Spain) was investigated by integrating U–Pb geochronology, cathodoluminescence and back-scattered SEM imaging, laser-ablation inductively coupled plasma mass spectrometry analyses and Raman spectroscopy to examine the conditions of magmatic zircon growth and the variable extent and mechanisms of the Alpine modifications. Zircon from inheritance-rich gneiss consists of two main domains: inherited (Neoproterozoic-to-Early Paleozoic and Devonian) cores and magmatic overgrowths, which provided 206Pb/238U concordant ages of 286 ± 3 Ma. In inheritance-poor gneiss, zircons consist of magmatic cores and very altered rims defining a discordia with an upper intercept with the Concordia at 287 + 21 –22 Ma and a lower intercept at 20.8 + 48.6 –20.8 Ma. Magmatic domains of zircon from inheritance-rich gneiss have lower rare-earth element (REE) contents than magmatic domains from inheritance-poor gneiss, reflecting the less evolved nature of the melt. Altered domains in zircon from inheritance-poor gneisss how greater U concentrations, lower REE concentrations and lower Th/U ratios relative to the cores, interpreted as representing Pb loss from the U-rich magmatic domains during the Alpine event. Morphological changes within single grains and between populations reflects the evolution during magmatic cooling. We show that, whereas classic methods allow two different interpretations for the geodynamic setting of the two types of gneisses, a complete study of composition, morphology and structure of zircon can help to decide that a model based on a common source for the granitic melt better fits the zircon characteristics than a model based on melts generated in two different geotectonic settings.
Mendeleevite-(Nd), (Cs,□)6 (□,Cs)6 (□,K)6 (REE,Ca)30(Si70O175)(OH,H2O,F)35, a new mineral from the Darai-Pioz alkaline massif, Tajikistan
Authors: Agakhanov Atali A. , Pautov Leonid A. , Sokolova Elena , Hawthorne Frank C. , Yu Karpenko Vladimir , Siidra Oleg I. , Garanin Viktor K. 
Published: March 2017

AbstractMendeleevite-(Nd), (Cs,□)6(□,Cs)6(□,K)6(REE,Ca)30(Si70O175)(OH,H2O,F)35 is a new mineral from the Darai-Pioz alkaline massif, Tajikistan. Mendeleevite-(Nd) was found in a pectolite aggregate in silexites (quartz-rich rocks) which consist of fine to medium pectolite grains, quartz, aegirine and fluorite, with minor khvorovite, mendeleevite-(Ce), sokolovaite, hyalotekite, orlovite, kirchhoffite, pekovite, neptunite, zeravshanite, senkevichite, nordite-(Nd), alamosite, pyrochlore-group minerals and baratovite. Mendeleevite-(Nd) forms colourless cubic crystals 10–40 μm in size; it has a vitreous lustre and a Mohs hardness of 5–5.5; Dmeas. = 3.20(2) g/cm3, Dcalc. = 3.155 g/cm3. Mendeleevite-(Nd) is optically isotropic, with the refractive index n = 1.582(2). Mendeleevite-(Nd) is cubic, space group Pm3̄, a = 21.9106(4) Å; Z = 2. The six strongest reflections in the powder X-ray diffraction pattern are [d (Å), I (%), (h k l)] are: 11.01, 100, (0 0 2); 15.63, 55, (0 1 1); 3.47, 42, (2 0 6); 3.099, 42, (3 4 5); 2.192, 42, (0 0 10); 1.819, 41, (3 6 10). Chemical analysis by electron microprobe gave SiO2 42.30, Ce2O3 10.12, La2O3 3.60, Nd2O3 16.19, Pr2O3 2.79, Sm2O3 4.19, Gd2O3 1.69, Eu2O3 0.47, SrO 2.99, CaO 2.20, Cs2O 8.50, K2O 0.85, H2O 3.85, F 1.25, –O = F2 –0.53, sum 100.46 wt.%, with H2O calculated by analogy with mendeleevite-(Ce). The empirical formula based on 210 (O + F) apfu, with F + OH + H2O = 35 pfu, is Cs6(□4.20K1.80)∑6{[(Nd9.57Ce6.13Sm2.39La2.20Pr1.68Gd0.93Eu0.27)∑23.17(Ca3.90Sr2.87)∑6.77]∑29.94□0.06}∑30(Si70.03O175)(OH14.47F6.54)∑21.01 (H2O)14, Z = 2. The simplified and ideal formulae are (Cs,□)6 (□,Cs)6(□,K)6 (REE,Ca)30 (Si70O175)(OH, H2O,F)35 and Cs6(REE23Ca7)(Si70O175)(OH,F)19(H2O)16, respectively. The compatibility index (from measured density) = – 0.039 (excellent). Mendeleevite-(Nd) is a Nd analogue of mendeleevite-(Ce), (Cs,□)6(□,Cs)6(□,K)6(REE,Ca,□)30(Si70O175)(H2O,OH,F,□)35. Both minerals are named after Dmitri Mendeleev (1834–1907), the great Russian chemist, author of the periodic table of chemical elements, who has had a significant impact on the development of natural sciences and industry, both in Russia and around the world.
Lithium and trace-element concentrations in trioctahedral micas from granites of different geochemical types measured via laser ablation ICP-MS
Authors: Breiter Karel , Vaňková Michaela , Galiová Michaela Vašinová , Korbelová Zuzana , Kanický Viktor 
Published: March 2017

AbstractThe compositions of trioctahedral micas from 51 samples of granitoids with different geochemical affiliations and grades of differentiation from the Bohemian Massif, Central Europe, were analysed using electron microprobe (major elements) and laser ablation inductively coupled plasma mass spectrometry (Li, Sc, Ga, Ge, Nb, In, Sn, Cs, Ta, W, Tl). The micas form a continuous evolutionary series from phlogopite to zinnwaldite. The phlogopites and biotites from the I-type rocks are characterized by 5.5–5.7 Si, 2.4–2.6 Al, <0.1 Li atoms per formula unit [apfu] and Mg/(Mg + Fe) = 0.4–0.8. The biotites from the S-type granites usually contain 5.3–5.7 Si, 3.2–3.6 Al, 0.1–0.3 Li apfu and Mg/(Mg + Fe) = 0.15–0.4. The annites and zinnwaldites from the rare-metal granites contain 5.7–6.8 Si, 3.2–3.8 Al, 0.6–2.6 Li apfu and Mg/(Mg + Fe) < 0.1. The concentrations of F, Rb, Cs and Tl increase from the phlogopites and biotites to zinnwaldites: F 0.1 → 8 wt.%, Rb2O 0.05 → 1.7 wt.%, Tl 2 → 50 ppm and Cs 40 → 2000 ppm. The concentrations of Sn, Nb, Ta and W in phlogopites and biotites from the I- and S-type granitoids generally correlate with those of the parent rocks and reach values of (in ppm) 20–100 Sn, 20–250 Nb, 1–20 Ta and <5 W. The highest concentrations were found in the Li-annites in the relatively early facies of rare-metal granites (in ppm): 250–600 Sn, 400–600 Nb, 60–120 Ta and 50– 120 W. The zinnwaldites in the late rare-metal granites facies are impoverished in these elements, which is explained by contemporaneous crystallization of cassiterite and columbite. Lithium enters the crystal lattice of trioctahedral micas via the exchange vector Li3□Si3Fe–6Al–1up to concentrations of ∼2.5 wt.% Li2O (1.5 apfu Li). At higher Li concentrations, Li is incorporated through the exchange vector Li3Si1□–1Fe–2Al–1.
Lower levels of vitamin A are associated with increased gastrointestinal graft-versus-host disease in children
Authors: Lounder Dana T. , Khandelwal Pooja , Dandoy Christopher E. , Jodele Sonata , Grimley Michael S. , Wallace Gregory , Lane Adam , Taggart Cynthia , Teusink-Cross Ashley C. , Lake Kelly E. , Davies Stella M. 
Published: March 2017

Key PointsVitamin A levels below the median at day 30 posttransplant are associated with increased cumulative incidence of GI GVHD in children. Potential mechanisms include increased intestinal permeability and increased lymphocyte homing to the intestine.
Information Avoidance
Authors: Golman Russell , Hagmann David , Loewenstein George 
Published: March 2017

We commonly think of information as a means to an end. However, a growing theoretical and experimental literature suggests that information may directly enter the agent's utility function. This can create an incentive to avoid information, even when it is useful, free, and independent of strategic considerations. We review research documenting the occurrence of information avoidance, as well as theoretical and empirical research on reasons why people avoid information, drawing from economics, psychology, and other disciplines. The review concludes with a discussion of some of the diverse (and often costly) individual and societal consequences of information avoidance. (JEL D82, D83)
Report of the Nomenclature Committee for Algae: 15
Authors: Prud’homme van Reine Willem F. 
Published: March 2017

SummaryThree names are recommended for conservation against the names indicated: Gelidium bipectinatum (Rhodophyceae) against Fucus serra; Scrippsiella (Dinophyceae) against Heteraulacus and Goniodoma; and Gloeobacter violaceus (Cyanophyceae) against Aphanothece caldariorum, Gloeothece coerulea, and Gloeothece linearis, while two names are recommended for conservation with a conserved type: Chara hispida (Characeae) and Gloeothece (Cyanophyceae). Three names are recommended for outright rejection, Jania verrucosa (Rhodophyceae), Cyanospira (Cyanophyceae) and Goniodomataceae (Dinophyceae), but the name Gonyaulax catenella (Dinophyceae) should not be rejected. The Committee concluded that the names Geisleria Nitschke (Fungi) and Geissleria Lange‐Bert. & Metzeltin (Bacillariophyceae) are not sufficiently alike to be confused.
Hybridization and long‐distance colonization in oat‐like grasses of South and East Asia, including an amended circumscription of Helictotrichon and the description of the new genus Tzveleviochloa (Poaceae)
Authors: Wölk Alexandra , Röser Martin 
Published: March 2017

AbstractThe phylogenetic relationships of 31 genera of the traditional grass tribe Aveneae, with focus on Southeast Asian species of Helictotrichon, were examined using DNA sequences of the plastid matK‐psbA region, nuclear ITS, the nuclear single‐copy gene topoisomerase 6 (Topo6) spanning two introns and morphology. A molecular phylogenetic analysis was performed for 121 species applying maximum parsimony and Bayesian methods. Additionally we surveyed 11 Southeast Asian taxa for structural spikelet characters including lemmas, lodicules and ovaries. The phylogenetic results of the three molecular markers revealed that several Southeast Asian species traditionally accommodated in Helictotrichon are misplaced in this genus except for H. abietetorum, H. hideoi and H. leianthum. The placement of H. polyneurum and H. sumatrense in the genus Helictotrichon requires further investigation as suggested by morphological and preliminary molecular data. Due to the occurrence of different sequence types of ITS and Topo6, both nuclear DNA markers suggested an allopolyploid origin for several Southeast Asian taxa. (1) In Helictotrichon parviflorum and H. potaninii two different sequence types of Topo6 occur, closely similar to those of Trisetum and Helictotrichon, respectively. Nuclear ITS data of both species point to affinities with Trisetum and related genera but not to Helictotrichon. Both species belong to a hitherto unknown genus that is morphologically distinct from Trisetum and Helictotrichon and is named Tzveleviochloa. (2) Two copy types (A and B) of Topo6 previously identified in African Trisetopsis, a genus encompassing predominantly sub‐Saharan species that traditionally had been ascribed to Helictotrichon, also occur in two Southeast Asian species, i.e., H. junghuhnii and H. virescens. In agreement with morphological data both species need to be transferred to Trisetopsis. This expands the hitherto known eastern edge of the range of Trisetopsis from the Arabian Peninsula to China. (3) Additionally, the Chinese H. altius has a copy type sequence of Topo6 similar to that of Trisetopsis but not of Helictotrichon in its genome, whereas its plastid DNA fits Helictotrichon and relatives. Along with morphological characters this supports intermediacy between Trisetopsis and Helictotrichon. Therefore H. altius is probably an intergeneric hybrid, here named ×Trisetopsotrichon altius. The taxonomically difficult genus Helictotrichon s.l. in tropical to temperate southeastern Asia becomes disassembled into Helictotrichon s.str., the new genus Tzveleviochloa, gen. nov., and the nothogenus ×Trisetopsotrichon, nothogen. nov. The following combinations are introduced: Trisetopsis aspera, comb. nov., T. junghuhnii, comb. nov., T. virescens, comb. nov., ×Trisetopsotrichon altius, comb. nov., Tzveleviochloa burmanica, comb. nov., T. parviflora, comb. nov., T. potaninii, comb. nov.
Deadlines, Workflows, Task Sorting, and Work Quality
Authors: Balasubramanian Natarajan , Lee Jeongsik , Sivadasan Jagadeesh 
Published: March 2017

Deadlines are often used to manage the time of valuable human capital. In this multimethod paper, we propose a theoretical framework grounded in a formal model that encapsulates the key drivers and consequences of deadline-related time pressures on workflows, task sorting, and work quality. We use large-scale data on patent filings, along with insights from primary data collection, to test our hypotheses. In line with our predictions, we find clustering of patent filings around month-ends, with month-end applications being more complex than those filed on other days. Consistent with time pressure reducing work quality, we find that work quality is lower for tasks completed at month-ends, more so for process measures of quality than for outcome measures. Calibration of our model to the data allows us to shed light on the benefits of deadlines and suggests small levels of task acceleration but potentially larger working capital–related benefits for law firms. The online appendix is available at https://doi.org/10.1287/mnsc.2016.2663 . This paper was accepted by Lee Fleming, entrepreneurship and innovation.
Sensitivity to Serial Dependency of Input Processes: A Robust Approach
Authors: Lam Henry 
Published: March 2017

Procedures in assessing the impact of serial dependency on performance analysis are usually built on parametrically specified models. In this paper, we propose a robust, nonparametric approach to carry out this assessment, by computing the worst-case deviation of the performance measure due to arbitrary dependence. The approach is based on optimizations, posited on the model space, that have constraints specifying the level of dependency measured by a nonparametric distance to some nominal independent and identically distributed input model. We study approximation methods for these optimizations via simulation and analysis of variance. Numerical experiments demonstrate how the proposed approach can discover the hidden impacts of dependency beyond those revealed by conventional parametric modeling and correlation studies. The online appendix is available at https://doi.org/10.1287/mnsc.2016.2667 . This paper was accepted by Assaf Zeevi, stochastic models and simulation.