bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of Ultrasound-Guided Serratus Plane Block on Postoperative Quality of Recovery and Analgesia After Video-Assisted Thoracic Surgery: A Randomized, Triple-Blind, Placebo-Controlled Study
Authors: Kim Do-Hyeong , Oh Young Jun , Lee Jin Gu , Ha Donghun , Chang Young Jin , Kwak Hyun Jeong 
Published: January 2018

BACKGROUND:
The optimal regional technique for analgesia and improved quality of recovery after video-assisted thoracic surgery (a procedure associated with considerable postoperative pain) has not been established. The main objective in this study was to compare quality of recovery in patients undergoing serratus plane block (SPB) with either ropivacaine or normal saline on the first postoperative day. Secondary outcomes were analgesic outcomes, including postoperative pain intensity and opioid consumption.

METHODS:
Ninety patients undergoing video-assisted thoracic surgery were randomized to receive ultrasound-guided SPB with 0.4 mL/kg of either 0.375% ropivacaine (SPB group) or normal saline (control group) after anesthetic induction. The primary outcome was the 40-item Quality of Recovery (QoR-40) score at 24 hours after surgery. The QoR-40 questionnaire was completed by patients the day before surgery and on postoperative days 1 and 2. Pain scores, opioid consumption, and adverse events were assessed for 2 days postoperatively.

RESULTS:
Eighty-five patients completed the study: 42 in the SPB group and 43 in the control group. The global QoR-40 scores on both postoperative days 1 and 2 were significantly higher in the SPB group than in the control group (estimated mean difference 8.5, 97.5% confidence interval [CI], 2.1–15.0, and P = .003; 8.5, 97.5% CI, 2.0–15.1, and P = .004, respectively). The overall mean difference between the SPB and control groups was 8.5 (95% CI, 3.3–13.8; P = .002). Pain scores at rest and opioid consumption were significantly lower up to 6 hours after surgery in the SPB group than in the control group. Cumulative opioid consumption was significantly lower up to 24 hours postoperatively in the SPB group.

CONCLUSIONS:
Single-injection SPB with ropivacaine enhanced the quality of recovery for 2 days postoperatively and improved postoperative analgesia during the early postoperative period in patients undergoing video-assisted thoracic surgery.
Predicting Heparin Responsiveness in Children Before Cardiopulmonary Bypass: A Retrospective Cohort Study
Authors: Nakamura Sayaka , Honjo Osami , Crawford-Lean Lynn , Foreman Celeste , Sano Minako , O’Leary James D. 
Published: January 2018

BACKGROUND:Inadequate or excess administration of unfractionated heparin for cardiopulmonary bypass (CPB) can cause significant harm. Age-dependent differences in the pharmacodynamics and pharmacokinetics of heparin contribute to increased variability of heparin responsiveness in children. The aims of the current study were to (1) examine the correlation between predicted and observed heparin responsiveness in children before CPB measured using the Hemostasis Management System (HMS) Plus (Medtronic, Minneapolis, MN), (2) describe age-specific reference intervals for heparin sensitivity index (HSI) observed in children, and (3) test predictive models of HSI using preoperative clinical and laboratory data.METHODS:In this retrospective cohort study, children (ages ≤17 years) who required therapeutic heparinization for CPB in a 40-month period between September 2010 and December 2013 were investigated. Children weighing ≥45 kg or with a height ≥142 cm were excluded. HSI was defined as the difference between activated clotting time after heparin administration and the baseline activated clotting time divided by the heparin-loading dose (IU) per kilogram. Lin’s concordance correlation coefficient was used for the primary analysis of the relationship between predicted and observed HSI. Reference intervals were calculated for HSI using medians and 2.5% and 97.5% percentiles according to established guidelines for clinical and laboratory standards. Nonparametric regression analyses were used to model the relationship between HSI (dependent variable) and preoperative covariates (independent variables).RESULTS:A total of 1281 eligible children were included in the final analysis. Overall, there was a moderate correlation between predicted and observed HSI measured using HMS Plus System (rho_c = 0.46; 95% confidence interval, 0.41–0.50;P< .001). Sixty-five percent (829 of 1281) of predicted HSI values were less than observed. From adjusted regression models, HSI was best predicted by preoperative international normalized ratio, platelet count, and weight, but this model accounted for only 25% of the variance in HSI.CONCLUSIONS:In a large cohort of children, heparin responsiveness before CPB was not reliably predicted by either in vitro measurement using the HMS Plus System or commonly available preoperative clinical and laboratory data. We describe age-specific reference intervals for HSI in children, and we anticipate that these data will aid the identification of heparin resistance in this population.
Zurich to Berlin—“Where” Are We Now with the Concussion in Sport Group?
Authors: Pusateri Margaret E. , Hockenberry Brandon J. , McGrew Christopher A. 
Published: January 2018

AbstractThe Concussion in Sport Group recently published its highly anticipated fifth consensus statement on sports-related concussion. The latest iteration features a new organizational format—the “11 Rs” and has input from a wider range of health care professionals, organizations, and experts in the field from both the sport concussion area and from related areas outside of sport. The stated objective of this current document is to “build on the principles outlined in previous statements and develop further conceptual understanding of sports-related concussion.” Its intended audience is “physicians and health care providers who are involved in athlete care, whether at a recreational, elite, or professional level.” We review significant updates including recommendations for sideline evaluation, return to play, and return to learn in athletes with sports-related concussion.
Active and Inactive Leg Hemodynamics during Sequential Single-Leg Interval Cycling
Authors: GORDON NICOLE , ABBISS CHRIS R. , IHSAN MOHAMMED , MAIORANA ANDREW J. , PEIFFER JEREMIAH J. 
Published: January 2018

ABSTRACT

Introduction
Leg order during sequential single-leg cycling (i.e., exercising both legs independently within a single session) may affect local muscular responses potentially influencing adaptations. This study examined the cardiovascular and skeletal muscle hemodynamic responses during double-leg and sequential single-leg cycling.

Methods
Ten young healthy adults (28 ± 6 yr) completed six 1-min double-leg intervals interspersed with 1 min of passive recovery and, on a separate occasion, 12 (six with one leg followed by six with the other leg) 1-min single-leg intervals interspersed with 1 min of passive recovery. Oxygen consumption, heart rate, blood pressure, muscle oxygenation, muscle blood volume, and power output were measured throughout each session.

Results
Oxygen consumption, heart rate, and power output were not different between sets of single-leg intervals, but the average of both sets was lower than the double-leg intervals. Mean arterial pressure was higher during double-leg compared with sequential single-leg intervals (115 ± 9 vs 104 ± 9 mm Hg, P < 0.05) and higher during the initial compared with second set of single-leg intervals (108 ± 10 vs 101 ± 10 mm Hg, P < 0.05). The increase in muscle blood volume from baseline was similar between the active single leg and the double leg (267 ± 150 vs 214 ± 169 μM·cm, P = 0.26). The pattern of change in muscle blood volume from the initial to second set of intervals was significantly different (P < 0.05) when the leg was active in the initial (−52.3% ± 111.6%) compared with second set (65.1% ± 152.9%).

Conclusions
These data indicate that the order in which each leg performs sequential single-leg cycling influences the local hemodynamic responses, with the inactive muscle influencing the stimulus experienced by the contralateral leg.
Global Open Data in Agriculture and Nutrition (GODAN) initiative partner network analysis
Authors: Musker Ruthie , Schaap Ben 
Published: January 2018

Background: Ensuring healthy, safe and nutritious food for everyone is a global concern. Accessing the information to make the correct decisions regarding food security can be challenging. Open data has been shown to help solve practical problems related to agriculture and nutrition, enabling effective decision-making. In order to create a global data ecosystem that benefits everyone, a wide range of stakeholders must be included in the conversations. The GODAN initiative involves a network of over 500 partner organizations committed to open data in agriculture and nutrition. Methods: We analysed data from a survey of the partner organizations, with 225 respondents, to determine open data activities, including challenges, use of open data, stakeholder involvement and future directions. Respondents were asked a variety of free text and multiple choice questions. Results: 160 partners had at least one open data activity, 65 did not, or did not know. Of the 160, 36 had a second activity. Overall, GODAN partners are developing 200 open data activities. Agriculture is the most common focus for an open data activity. Nutrition-only activities are strongly underrepresented. The most frequently mentioned challenge was cost, which is linked to data governance, management, and human capacity; many do not have the funding to begin or maintain open data activities. Conclusions: The most common challenges were the ones related to the data itself, including how to access it, manage it, and how to keep the sensitive data secure. GODAN is already focusing on these issues through the Responsible Data and Data Ownership pieces. Capacity building, and empowering partners with the tools they need to act, is one of the most effective actions available for GODAN. Funding for open data, as well as research to create more sustainable business models, should be the focus of the open data agenda.
The nurse's role in assessing and responding to patients' spiritual needs
Authors: Ross Linda Anne 
Published: January 2018

The spiritual dimension of health care is becoming increasingly prominent, particularly in terminal care. It is not always clear, however, what spiritual needs are or who has responsibility for spiritual care. The first part of this paper takes the form of a literature review which examines the spiritual dimension and spiritual need. Spiritual needs, which may be particularly acute during terminal illness, are considered broader than religious needs and include the need for meaning, purpose, fulfilment, hope/will to live, and belief and faith in self, others and God. The role of the nurse in assessing and responding to patients' spiritual needs is addressed in the second part of the paper, with specific reference to the author's doctoral study. There is indication from this study that certain factors related to the patient, nurse, environment and other professionals may hinder the fulfilment of patients' spiritual needs. By addressing these factors it may be possible to improve spiritual care and therefore the quality of dying patients' remaining days.
Whom to help? An exploration of the assessment of grief
Authors: Walshe Catherine 
Published: January 2018

Palliative care, and the nursing care associated with it, includes the time around bereavement. Assessment of whether people are at risk of adverse bereavement consequences or suffer such consequences during their time of grief is important. Such assessment, which palliative care nurses are ideally placed to perform, can target those who need more support and intervention. This review investigates factors which it is important to recognise during nursing assessment of risk and outcome, with particular emphasis on the use of published tools. Three main recommendations are made: for provision of education about grief assessment for nurses; for more careful choosing and use of assessment tools; and for careful consideration of timing of assessment.
Embodied childbirth
Authors: Ruben Joy 
Published: January 2018

Abstract
Worship of the body and its wisdom was slowly phased out as modern religion and science came to power. The impact of this destruction of reverence for the body is still felt today in our violent and disembodied culture of childbirth. Women’s wisdom is resisted by modern medical practices, and the natural process of birth is largely treated as a medical emergency. This shift away from embodied wisdom has shamed women for embracing their bodies and created unnecessary risk in child-birth. In the United States of America, the maternal mortality rate is on the rise, which is unusual for developed countries. Embodied wisdom is needed to return sanctity to childbirth. It can be resurrected through the use of embodiment practices such as the Feldenkrais Method, Leadership Embodiment and Bones for Life with birthing mothers.
Woman, body, earth and spirit: Journeys of descent through myth, embodiment and movement practice
Authors: Hartley Linda 
Published: January 2018

Abstract
In this article I describe some personal journeys, inwards through the deepest layers of the psyche, to discover embodied understanding of what I call the deep feminine, or the feminine ground of being. I explore some myths and ancient stories of the Goddess that reflect the journey of healing and transformation through psychological descent, and can guide us through such ordeals. As C. G. Jung discovered, myths and archetypes are rooted in the instinctual body; as a somatic movement practitioner and transpersonal and body-oriented psychotherapist, my own journeys led me to intuitive appreciations of the somatic sources of mythic journeys that have particular relevance to contemporary women seeking healing/wholeness and spiritual renewal.
The myth of Inanna, the oldest known myth of the Goddess’s descent to the Underworld, affirms the truth that our healing and spiritual journey takes us through a process of ‘endarkenment’, in order to reach wholeness and discover the light of spirit within. The Goddess Lilith also represents the ‘dark’ side of the feminine, which we need to balance and reconcile with our upperworldly nature. La Loba, Wild Woman, shows us a path towards rebirth and revival of our soul and spirit. These ancient and timeless tales offer guidance and reflection for contemporary women, and also men exploring the feminine within their own psyches.
Symbols of the Goddess in Balkan women’s dance
Authors: Shannon Laura 
Published: January 2018

Abstract
Communal dance has been a primary means of worship in Eastern Europe and the Near East for over 9000 years, depicted in rock art and pottery fragments showing circles of dancing women. Existing women’s dance traditions of the Balkans may be direct descendants of these ancient rituals, and may offer living links to matrifocal Goddess cultures of Neolithic Old Europe. Women’s dances and textiles incorporate symbols such as the circle, sun, spiral, zigzag, and Tree of Life, which can be identified with the Goddess. Traditional dance circles, both past and present, also emphasize ancient values of community, connection, cooperation, shared leadership, and peace. Even as these dances change in their places of origin, they are being given new life as an embodied spiritual practice embraced by dancers all over the world. The contemporary movement practice of women’s ritual dances can offer experiences of healing, insight, and transformation to contemporary women from different cultures.
Cognitive distortion, translation distortion and poetic distortion as semiotic shifts
Authors: Osimo Sofia , Osimo Bruno 
Published: January 2018

Abstract
Both interlingual translation shifts and poetic production can be seen from a semiotic perspective in terms of mental filtering. The shared ground of the three processes - cognition, translation, versification - is to be found in the semiotic perspective: signs (prototext, reality, perception) are interpreted and worked through (mind, interpretants, cognition) and give as an output an object (metatext, poem, worldview). By trying to classify the shifts resulting from such processes - distortions - with a semiotically shared grid of categories, the hypothesis is that the categories themselves - already existing within the separate fields - can be reciprocally fine-tuned. The very notion of “shift” - derived from translation criticism, and in particular from the prototext-metatext comparison - becomes in this hypothesis a connection transforming the shifts possible in the other mentioned fields into mutual benchmarks.
Ethnotextual mental translation and self-translation in African literature
Authors: Benabed Fella 
Published: January 2018

AbstractInterest in African literature and translation is relatively new; it mainly emerged in the 1990s with the postcolonial turn in translation studies, under the influence of the cultural turn, the polysystems theory and the “Manipulation School”. Many African writers describe themselves as intercultural translators; they hover over the following questions: Is it a form of selfdenigration not to use one’s mother tongue as a medium of literary creation? How can their literary creations account for their postcolonial experience in the languages of former colonizers? Can these languages render the specificities of their distinct cultural worldviews? The linguistic choice made by African writers is hence highly political because it involves a compromise that rests on power relations. Their writing often involves a sort of translation from Source Language (SL) to Target Language (TL) whether through ethnotextual mental translation or self-translation.
Genotype-by-environment interaction and yield stability analysis in sorghum (Sorghum bicolor (L.) Moench) genotypes in North Shewa, Ethiopia
Authors: Admas Sintayehu , Tesfaye Kassahun 
Published: January 2018

Abstract
A multi-environment sorghum variety trial comprised of nine genotypes along with one standard check, “yeju”, was carried out in the main cropping seasons of the period of 2006–2008. The objective of this research was to identify a stable and better-yielding sorghum variety under the conditions of the sorghum-growing area of North Shewa, Ethiopia. The experiment was arranged in randomized complete block design replicated three times within an experiment. AMMI analysis based on grain yield data revealed that genotypes ICSV 1112BF, 82 LPYT-2 # 5x81ESIP 46, and PGRC/E #222880 were superior to the standard check both in grain yield and stability, and hence these genotypes have been verified, and the genotype PGRC/E #222880 has been registered by the national variety-releasing technical and standing committee by the given name “Chare” for commercial production for the North Shewa sorghum-growing areas.
Performance, Luck and Equality: An Experimental Analysis of Subjects’ Preferences for Different Allocation Criteria
Authors: Becchetti Leonardo , Antoni Giacomo Degli , Ottone Stefania , Solferino Nazaria 
Published: January 2018

Abstract
We perform an experimental analysis to investigate participants’ choices of allocative criteria under different conditions. We document that performance-based criteria guaranteeing a minimal egalitarian base are widely preferred by both neutral spectators and stakeholders without information on relative payoffs, although popularity among stakeholders is mostly due to self-interest considerations and optimism concerning their expected performance. Information regarding the distribution of payoffs under different criteria dramatically reduces such choice because the self-interest motive directly emerges, and most players opt to revise their decision in favor of the criterion maximizing their own payoff.
Systematic comparison of routine laboratory measurements with in-hospital mortality: ICU-Labome, a large cohort study of critically ill patients
Authors: Alkozai Edris M. , Mahmoodi Bakhtawar K. , Decruyenaere Johan , Porte Robert J. , Oude Lansink-Hartgring Annemieke , Lisman Ton , Nijsten Maarten W. 
Published: January 2018

AbstractBackground:In intensive care unit (ICU) patients, many laboratory measurements can be deranged when compared with the standard reference interval (RI). The assumption that larger derangements are associated with worse outcome may not always be correct. The ICU-Labome study systematically evaluated the univariate association of routine laboratory measurements with outcome.Methods:We studied the 35 most frequent blood-based measurements in adults admitted ≥6 h to our ICU between 1992 and 2013. Measurements were from the first 14 ICU days and before ICU admission. Various metrics, including variability, were related with hospital survival. ICU- based RIs were derived from measurements obtained at ICU discharge in patients who were not readmitted to the ICU and survived for >1 year.Results:In 49,464 patients (cardiothoracic surgery 43%), we assessed >20·106measurements. ICU readmissions, in-hospital and 1-year mortality were 13%, 14% and 19%, respectively. On ICU admission, lactate had the strongest relation with hospital mortality. Variability was independently related with hospital mortality in 30 of 35 measurements, and 16 of 35 measurements displayed a U-shaped outcome-relation. Medians of 14 of 35 ICU-based ranges were outside the standard RI. Remarkably, γ-glutamyltransferase (GGT) had a paradoxical relation with hospital mortality in the second ICU week because more abnormal GGT-levels were observed in hospital survivors.Conclusions:ICU-based RIs for may be more useful than standard RIs in identifying ICU patients at risk. The association of variability with outcome for most of the measurements suggests this is a consequence and not a cause of a worse ICU outcome. Late elevation of GGT may confer protection to ICU patients.
Diagnosis of acute pediatric appendicitis from children with inflammatory diseases by combination of metabolic markers and inflammatory response variables
Authors: Yu Mengjie , Xiang Tianxin , Wu Xiaoping , Zhang Shouhua , Yang Wenlong , Zhang Yu , Chen Qiang , Sun Shuilin , Xie Baogang 
Published: January 2018

Abstract

Background:
The discovery of new metabolic markers may be helpful for early diagnosis of acute pediatric appendicitis (APA). However, no studies have been reported regarding identification of potential metabolic markers for the APA diagnosis by metabonomics.

Methods:
Serum samples of APA (n=32), non-appendicitis inflammation (NAI, n=32) and healthy children (HS, n=65) were analyzed by the 1H NMR-based metabonomics. A logistic regression model was established to screen the most efficient markers combinations for classification. Forty double-blind samples were further validated the model.

Results:
Nine blood metabolites that were different in the APA group from other groups were identified. To differentiate APA from HS, single variable of acetate, formate, white blood cell (WBC) and C-reactive protein (CRP) showed a high diagnostic value (area under the receiver operating characteristic [AUROC]<0.92), while they had a weak diagnostic value (AUROC<0.77) for identifying the APA and NAI. By contrast, the AUROC values of leucine (0.799) were higher than that of WBC and CRP. A combination of five variables, i.e. leucine, lactate, betaine, WBC and CRP, showed a high diagnostic value (AUROC=0.973) for the APA discriminating from the NAI, and the sensitivity and specificity were 93.8% and 93.7%, respectively. Further double-blind sample prediction showed that the accuracy of the model was 85% for 40 unknown samples.

Conclusions:
The current study provides useful information in our understanding of the metabolic alterations associated with APA and indicates that measurement of these metabolites in serum effectively aids in the clinical identification of APA.