bluuebunny/crossref_metadata_2025_split huggingface dataset:
Doing it our Way: Love and marriage in Kolkata middle-class families
Authors: DONNER HENRIKE 
Published: April 2016

AbstractWith the exception of a few anthropologists working on gender, much of the recent literature on emerging intimate modernities in South Asia, and the middle class in India in particular, seems to support a view of social relationships evolving in a kind of linear development towards free choice, individualism, and identities based on sexual preference. This imagery is particularly prominent in the representation and self-representation of metropolitan, educated middle-class youths, whose views dominate popular media representations and are associated with secularism, individualism, and independence from family and community. In this article I argue that apart from the ostensibly overwhelming transformations that discourses on coupledom, love, choice and self-realization bring in their wake, new ways of choosing a spouse and of conducting conjugal relations among middle-class urbanites have to be interpreted in relation to much more subtle and long-standing social transformations as well as existing institutional forms, in particular the practical implications of patrilocality and the ideology and reality of the joint family. Based on fieldwork with Bengali-speaking middle-class families in Kolkata spanning two decades, the article charts continuities and subtle shifts in the way ‘love’ and ‘marriage’ are related in conversations, and how young women and their parents negotiate marriage in the context of middle-class consumerism, status competition, and uncertainty.
Participation of natural resource managers on editorial boards of conservation and applied natural resource journals
Authors: Carter Sarah K. , Fayram Andrew H. 
Published: April 2016

AbstractA gap between research and management exists in numerous natural resource fields. This can lead to management actions that are based on experience rather than evidence and may be less effective as a result. The gap may be partly attributable to research not being relevant, timely or accessible for managers. Editorial boards of peer-reviewed journals are responsible for determining the relevance of submitted manuscripts for a journal's readership. Limited representation of natural resource managers on editorial boards may make it more difficult for journals to identify the topics and findings of most relevance for management, thus contributing to the research–management gap. We quantified the representation of natural resource managers on the editorial boards of 79 conservation and applied natural resource journals. We found that 65% of editors were affiliated with universities, 13% with research institutions, 12% with government agencies and 3% with NGOs. On average, 9% of editors were affiliated with an agency or organization responsible for managing or regulating natural resources. The proportion of managers on editorial boards did not differ significantly between natural resource fields or with journal impact factor. Potential benefits of greater integration of managers into the research and publishing process include selection of research topics with greater relevance for management, clearer statements of the management implications of research studies, and more frequent publication of research evaluating the effectiveness of management interventions. Further study is needed to evaluate whether greater participation of managers in the editorial review process may contribute to achieving these benefits.
Street Politics: Street Vendors and Urban Governance in China
Authors: Hanser Amy 
Published: April 2016

AbstractConflicts between urban street vendors and city regulators have become a common urban sight in Chinese cities today. This paper considers how visions of modern urban streets and sidewalks have helped to generate increasingly restrictive policies on street vending and spurred new forms of urban regulation and policing. While mostly an everyday routine of Chinese city life, the resulting vendor–chengguanconflicts dramatize state power in public and carry the latent danger of crowd violence in response. In particular, aggressive policing of highly visible city streets can at times produce a volatile “politics of the street” involving episodes of vendor resistance and even dramatic expressions of bystander solidarity which challenge these street-level expressions of state power.
Explicating concepts in reasoning from function to form by two-step innovative abductions
Authors: Kroll Ehud , Koskela Lauri 
Published: April 2016

AbstractThe mechanism of design reasoning from function to form is suggested to consist of a two-step inference of the innovative abduction type. First is an inference from a desired functional aspect to an idea, concept, or solution principle to satisfy the function. This is followed by a second innovative abduction, from the latest concept to form, structure, or mechanism. The intermediate entity in the logical reasoning, the concept, is thus made explicit, which is significant in following and understanding a specific design process, for educating designers, and to build a logic-based computational model of design. The idea of a two-step abductive reasoning process is developed from the critical examination of several propositions made by others. We use the notion of innovative abduction in design, as opposed to such abduction where the question is about selecting among known alternatives, and we adopt a previously proposed two-step process of abductive reasoning. However, our model is different in that the two abductions used follow the syllogistic pattern of innovative abduction. In addition to using a schematic example from the literature to demonstrate our derivation, we apply the model to an existing, empirically derived method of conceptual design called “parameter analysis” and use two examples of real design processes. The two synthetic steps of the method are shown to follow the proposed double innovative abduction scheme, and the design processes are presented as sequences of double abductions from function to concept and from concept to form, with a subsequent deductive evaluation step.
Overcoming design fixation: Design by analogy studies and nonintuitive findings
Authors: Moreno Diana P. , Blessing Luciënne T. , Yang Maria C. , Hernández Alberto A. , Wood Kristin L. 
Published: April 2016

AbstractDesign fixation is a phenomenon with important significance to many fields of design due to the potential negative impacts it may have in design outcomes, especially during the ideation stage of the design process. The present study aims to provide a framework for understanding, or at least probing, design fixation by presenting a review of existing defixation approaches, as well as metrics that have been employed to understand and account for design fixation. This study also describes the results of two design by analogy (DbA) methods, WordTree and SCAMPER, to overcome design fixation in an experiment that involved 97 knowledge-domain experts. The study outcomes are at least twofold: a common framework of metrics and approaches to overcome design fixation in a wide range of design problems and nonintuitive results for DbA approaches in design fixation and other related creativity metrics. The application of WordTree and SCAMPER shows that both methods yield increased novelty compared to a control, where the SCAMPER results are significantly higher than WordTree. It is also found that WordTree mitigates design fixation whereas SCAMPER appears to be ineffective for this purpose but effective to generate an increased quantity of novel ideas. These results demonstrate that both DbA methods provide de-fixation capabilities and enhance designers’ creativity during idea generation.
Intestinal barrier dysfunction: implications for chronic inflammatory conditions of the bowel
Authors: Miner-Williams Warren M. , Moughan Paul J. 
Published: April 2016

AbstractThe intestinal epithelium of adult humans acts as a differentially permeable barrier that separates the potentially harmful contents of the lumen from the underlying tissues. Any dysfunction of this boundary layer that disturbs the homeostatic equilibrium between the internal and external environments may initiate and sustain a biochemical cascade that results in inflammation of the intestine. Key to such dysfunction are genetic, microbial and other environmental factors that, singularly or in combination, result in chronic inflammation that is symptomatic of inflammatory bowel disease (IBD). The aim of the present review is to assess the scientific evidence to support the hypothesis that defective transepithelial transport mechanisms and the heightened absorption of intact antigenic proinflammatory oligopeptides are important contributing factors in the pathogenesis of IBD.
The next common and widespread bunting to go? Global population decline in the Rustic BuntingEmberiza rustica
Authors: EDENIUS LARS , CHOI CHANG-YONG , HEIM WIELAND , JAAKKONEN TUOMO , DE JONG ADRIAAN , OZAKI KIYOAKI , ROBERGE JEAN-MICHEL 
Published: April 2016

SummaryPopulations of several long-distance migratory songbirds in Eurasia are in peril, drastically illustrated by the recent range-wide population collapse in the Yellow-breasted BuntingEmberiza aureola. There are signals of a strong decline also in the Rustic BuntingE. rustica, but no range-wide assessment of population trends in this superabundant and widespread bunting species has yet been undertaken. The conservation status of Rustic Bunting is ‘Least Concern’ on the global IUCN Red List, but it has recently been upgraded to ‘Vulnerable’ on the European Red List. To assess the Rustic Bunting’s global conservation status we compiled, for the first time, population data across its breeding and wintering ranges. The analysis reveals a 75–87% decline in overall population size over the last 30 years and a 32–91% decline over the last 10 years. The trend estimates indicate that the long-term (30-year) range-wide population decline in the Rustic Bunting is of similar magnitude to two well-known examples of declining species within the same genus, the Yellow-breasted Bunting and the Ortolan BuntingE. hortulana. The magnitude of the range-wide population decline over the last 10 years suggests that the Rustic Bunting could be upgraded from ‘Least Concern’ to ‘Vulnerable’ or ‘Endangered’ on the IUCN global Red List. Agricultural intensification in the wintering range and intensified levels of disturbance, including logging and fire, in the breeding range could be important drivers of the range-wide population decline, and persecution could also contribute. Untangling threat factors and their interactions on Rustic Bunting is necessary for conservation, but hampered by our currently limited understanding of the relationships between population dynamics and different threats.
Effects of chronic treprostinil treatment on experimental right heart hypertrophy and failure
Authors: Axelgaard Sofie , Holmboe Sarah , Ringgaard Steffen , Hillgaard Thomas K. , Andersen Stine , Hansen Mona S. , Andersen Asger , Nielsen-Kudsk Jens E. 
Published: April 2016

AbstractBackgroundRight heart function is an important predictor of morbidity and mortality in pulmonary arterial hypertension and many CHD. We investigated whether treatment with the prostacyclin analogue treprostinil could prevent pressure overload-induced right ventricular hypertrophy and failure.MethodsMale Wistar rats were randomised to severe pulmonary trunk banding with a 0.5-mm banding clip (n=41), moderate pulmonary trunk banding with a 0.6-mm banding clip (n=36), or sham procedure (n=10). The banded rats were randomised to 6 weeks of treatment with a moderate dose of treprostinil (300 ng/kg/minute), a high dose of treprostinil (900 ng/kg/minute), or vehicle.ResultsPulmonary trunk banding effectively induced hypertrophy, dilatation, and decreased right ventricular function. The severely banded animals presented with decompensated heart failure with extracardial manifestations. Treatment with treprostinil neither reduced right ventricular hypertrophy nor improved right ventricular function.ConclusionsIn the pulmonary trunk banding model of pressure overload-induced right ventricular hypertrophy and failure, moderate- and high-dose treatment with treprostinil did not improve right ventricular function neither in compensated nor in decompensated right heart failure.
The comparative relationships between locations of the papillary muscles and electrophysiologic QRS axis in patients with atrioventricular septal defect and common as opposed to separate orifices in the valve guarding the common atrioventricular junction
Authors: Low Liying , Idriss Salim F. , Anderson Robert H. , Maynard Charles , Wagner Galen , Hakacova Nina 
Published: April 2016

AbstractBackgroundKnowledge regarding factors that influence deviation of the QRS axis is important when seeking to differentiate between physiological and pathological changes. We hypothesised that, in contrast to those patients with an atrioventricular septal defect and common atrioventricular junction permitting only atrial shunting, those associated with ventricular shunting would show no relationship between the positions of the papillary muscles and the degree of the leftward deviation of the QRS axis.MethodsWe compared the positions of endocardial origin of the papillary muscles, and the frontal plane QRS axis, in patients with atrioventricular septal defects and common atrioventricular junction permitting exclusively atrial as opposed to atrial and ventricular shunting.ResultsWe analysed 18 patients with atrial and ventricular shunting and 23 patients with exclusively atrial shunting. The correlation coefficient between the ratio of distances of the papillary muscles from the mid-septum and the amount of leftward deviation in the frontal plane QRS axis was 0.1 (p=0.4) in those with ventricular shunting and 0.26 (p=0.01) in those with exclusively atrial shunting.ConclusionsIn contrast to patients with the so-called primum form of atrioventricular septal defect, in whom the locations of the papillary muscles correlate with the degree of QRS axis, such relationships are lacking in patients with defects permitting both atrial and ventricular shunting. It may be, therefore, that the presence of ventricular shunting and/or their younger age causes pressure overload, which negates the leftward QRS forces caused by the abnormally positioned papillary muscles.
Paediatric cardiac surgery in a peripheral European region: is a joint programme a safe alternative to regionalisation?
Authors: Iacona Gabriele M. , Giamberti Alessandro , Abella Raul F. , Pomè Giuseppe , Agredo Julio , Mendieta Saúl G. , Forcano Antonio , Sobrado Concepción , Suaréz Josepha , Peñate Sonia , Melián Asunción , Volo Montserrat , González Rafael , Antúnez Marisa L. , Falcón Hipólito L. , Cabrera Francisco J. , Rubio Carlos , Fernández Javier , Suárez Pedro , Perera Cesar , Frigiola Alessandro 
Published: April 2016

AbstractBackgroundIn 2007, a partnership was initiated between a small-volume paediatric cardiac surgery unit located in Las Palmas de Gran Canaria, Spain, and a large-volume cardiac surgery unit located in Milan, Italy. The main goal of this partnership was to provide surgical treatment to children with CHD in the Canary Islands.MethodsAn operative algorithm for performing surgery in elective, urgent, and emergency cases was adopted by the this joint programme. Demographic and in-hospital variables were collected from the medical records of all the patients who had undergone surgical intervention for CHD from January, 2009 to March, 2013. Data were introduced into the congenital database of the European Congenital Heart Surgeons Association Congenital Database and the database was interrogated.ResultsIn total, 65 surgical mission trips were performed during the period of this study. The European Congenital Heart Surgeons Association Congenital Database documented 214 total patients with a mean age at operation of 36.45 months, 316 procedures in total with 198 cardiopulmonary bypass cases, 46 non-cardiopulmonary bypass cases, 26 cardiovascular cases without cardiopulmonary bypass, 22 miscellaneous other types of cases, 16 interventional cardiology cases, six thoracic cases, one non-cardiac, non-thoracic procedure on a cardiac patient with cardiac anaesthesia, and one extracorporeal membrane oxygenation case. The 30-day mortality was 6.07% (13 patients).ConclusionsA joint programme between a small-volume centre and a large-volume centre may represent a valid and reproducible model for safe paediatric cardiac surgery in the context of a peripheral region.
The role of mother’s education in the nutritional status of children in Serbia
Authors: Stamenkovic Zeljka , Djikanovic Bosiljka , Laaser Ulrich , Bjegovic-Mikanovic Vesna 
Published: April 2016

AbstractObjectiveThe present study aimed to identify the role of mother’s education in the nutritional status of children aged 2–5 years in Serbia.DesignNationally representative population-based study. Age- and gender-specific BMI percentiles of children were analysed. In accordance with the WHO growth reference, children with BMI less than the 5th percentile were considered undernourished. Logistic regression was used to calculate the association between mother’s education and other socio-economic determinants as possible confounders.SettingUNICEF’s fourth Multiple Indicator Cluster Survey, conducted in both Roma and non-Roma settlements in Serbia.SubjectsChildren (n 2603) aged 2–5 years (mean age 3·05 years).ResultsLess than 5 % of children aged 2–5 years were undernourished. There were significantly more undernourished children among the Roma population, in the capital of Serbia and among those whose mothers were less educated. There were statistically significant differences according to mother’s education in all socio-economic characteristics (ethnicity, area, region of living and wealth index). Mother’s level of education proved to be the most important factor for child’s nutritional status; place of living (region) was also associated.ConclusionsMother’s education is the most significant predictor of children’s undernutrition. It confirms that investment in females’ education will bring benefits and progress not only for women and their children, but also for society as a whole.
Vitamin D deficiency and depression among women from an urban community in a tropical country
Authors: Moy Foong Ming , Hoe Victor CW , Hairi Noran Naqiah , Vethakkan Shireene Ratna , Bulgiba Awang 
Published: April 2016

AbstractObjectiveTo determine the association of vitamin D status with depression and health-related quality of life among women.DesignThis was a cross-sectional study conducted among women in Kuala Lumpur, Malaysia. Sociodemographic characteristics, physical activity status, perceived depression and health-related quality of life were assessed via a self-administered questionnaire. Fasting blood samples were taken for the analysis of 25-hydroxyvitamin D, parathyroid hormone, fasting blood glucose and full lipid profile. Complex samples multiple logistic regression analysis was performed.SettingPublic secondary schools in Kuala Lumpur, Malaysia.SubjectsSeven hundred and seventy female teachers were included.ResultsThe mean age of participants was 41·15 (95 % CI 40·51, 41·78) years and the majority were ethnic Malays. Over 70 % of them had vitamin D deficiency (<20 ng/ml or <50 nmol/l) and two-thirds were at risk for depression. In the multivariate analysis, ethnic Malays (adjusted OR (aOR)=14·72; 95 % CI 2·12, 102·21) and Indians (aOR=14·02; 95 % CI 2·27, 86·59), those at risk for depression (aOR=1·88, 95 % CI 1·27, 2·79) and those with higher parathyroid hormone level (aOR=1·13; 95 % CI 1·01, 1·26) were associated with vitamin D deficiency, while vitamin D deficiency was negatively associated with mental health-related quality of life (Mental Component Summary) scores (aOR=0·98; 95 % CI 0·97, 0·99).ConclusionsVitamin D deficiency is significantly associated with depression and mental health-related quality of life among women in Kuala Lumpur, Malaysia.
Changes in caesarean section rates and milk feeding patterns of infants between 1986 and 2013 in the Dominican Republic
Authors: McLennan John D 
Published: April 2016

AbstractObjectiveThe relationship between caesarean sections (C-sections) and infant feeding varies between different samples and indicators of feeding. The current study aimed to determine the relationship between C-sections and five indicators of infant milk feeding (breast-feeding within 1 h after delivery, at the time of the survey (current) and ever; milk-based prelacteal feeds; and current non-breast milk use) over time in a country with a rapidly rising C-section rate.DesignSecondary data analysis on cross-sectional data from Demographic and Health Surveys from six different time points between 1986 and 2013.SettingDominican Republic.SubjectsInfants under 6 months of age.ResultsOver 90 % of infants were ever breast-fed in each survey sample. However, non-breast milk use has expanded over time with a concomitant drop in predominant breast-feeding. C-section prevalence has increased over time reaching 63 % of sampled infants in the most recent survey. C-sections remained significantly related to three infant feeding practices – the child not put to the breast within 1 h after delivery, milk-based prelacteal feeds and current non-breast milk use – in multivariate models that included sociodemographic control variables. However, current non-breast milk use was no longer related to C-sections when milk-based prelacteal feeds were factored into the model.ConclusionsReducing or avoiding milk-based prelacteal feeds, particularly among those having C-sections, may improve subsequent breast-feeding patterns. Simultaneously, efforts are needed to understand and help reduce the exceptionally high C-section rate in the Dominican Republic.
Human pregnane X receptor compromises the function of p53 and promotes malignant transformation
Authors: Robbins D , Cherian M , Wu J , Chen T 
Published: April 2016

AbstractThe pregnane X receptor (PXR) is well established as a nuclear receptor that has a central role in xenobiotic metabolism and disposition. However, emerging evidence suggests that PXR is also a regulator of apoptosis, promoting a malignant phenotype both in vitro and in vivo. The tumor suppressor p53 can be activated in the presence of DNA damage and induce cell cycle arrest to allow for DNA repair or, ultimately, apoptosis to suppress tumor formation. We previously identified p53 as a novel PXR-associated protein by using a mass spectrometric approach. In the current study, we identified a novel inhibitory effect of PXR on p53, revealing an anti-apoptotic function of PXR in colon carcinogenesis. PXR expression reduced p53 transactivation and the expression of its downstream target genes involved in cell cycle arrest and apoptosis by decreasing p53 recruitment to the promoter regions of these genes. Consistent with the inhibitory effect of PXR on p53, elevated PXR levels decreased doxorubicin- or nutlin-3a-mediated toxicity and promoted malignant transformation in colon cancer cells. Our findings show for the first time that PXR expression modulates p53 target gene promoter binding and contributes to the downregulation of p53 function in human colon cancer cells. These results define the functional significance of PXR expression in modulating p53-mediated mechanisms of tumor suppression.