bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical Care Follow-up Clinics
Authors: Lasiter Sue , Oles Sylwia K. , Mundell James , London Susan , Khan Babar 
Published: June 2016

Objective:
The purpose of this scoping review is to identify evidence describing benefits of interventions provided in intensive care unit (ICU) survivor follow-up clinics.

Background:
Advances in ICU treatments have increased the number of survivors who require specialized care for ICU-related sequelae. Intensive care unit survivor follow-up clinics exist, yet little is known about the nature and impact of interventions provided in such clinics. A scoping review of publications about in-person post-ICU follow-up care was undertaken.

Method:
Ten databases were searched yielding 111 relevant unique publication titles and abstracts. Sample heterogeneity supported using a scoping review method. After excluding nonrelated publications, 33 reports were fully reviewed. Twenty international publications were included that described ICU follow-up clinic interventions and/or outcomes.

Results:
Authors discussed very diverse interventions in 15 publications, and 9 reported some level of intervention effectiveness. Evidence was strongest that supported the use of prospective diaries as an intervention to prevent or improve psychological symptoms, whereas evidence to support implementation of other interventions was weak.

Conclusions:
Although ICU follow-up clinics exist, evidence for interventions and effectiveness of treatments in these clinics remains underexplored.

Implications:
Intensive care unit survivor follow-up clinics provide a venue for further interdisciplinary intervention research that could lead to better health outcomes for ICU survivors.
Comparative Effectiveness of Percutaneous Needle Aponeurotomy and Limited Fasciectomy for Dupuytren’s Contracture: A Multicenter Observational Study
Authors: Zhou Chao , Selles Ruud W. , Slijper Harm P. , Feitz Reinier , van Kooij Yara , Moojen Thybout M. , Hovius Steven E. R. 
Published: June 2016

Background:
Percutaneous needle aponeurotomy is a less invasive surgical alternative to limited fasciectomy for Dupuytren’s contracture, but appeared less efficacious in a previous randomized clinical trial. This study compared the effectiveness of both techniques in contemporary clinical practice.

Methods:
The authors evaluated prospectively gathered data from all patients who were treated with percutaneous needle aponeurotomy or limited fasciectomy between 2011 and 2014 at six hand surgery practice sites in The Netherlands. The degree of total active extension deficit, Michigan Hand Outcomes Questionnaire subscores, and complications evaluated at 6 to 12 weeks after treatment were compared after propensity score–based inverse-probability weighting to account for the differences in baseline characteristics between the treatment groups.

Results:
After inverse-probability weighting, 78 percutaneous needle aponeurotomy patients and 103 limited fasciectomy patients remained with similar characteristics (88 percent Tubiana grade I or II). The degree of total residual extension deficit at follow-up was similar between the weighted groups (percutaneous needle aponeurotomy, 21 degrees; limited fasciectomy, 18 degrees; p = 0.330). Furthermore, percutaneous needle aponeurotomy was associated with a lower mild complication rate (percutaneous needle aponeurotomy, 5.2 percent; limited fasciectomy, 24.3 percent; p < 0.001) and larger increases in the subdomain scores of satisfaction (p < 0.001), work performance (p < 0.001), activities of daily living (p = 0.009), and overall hand function (p = 0.001).

Conclusions:
This multicenter observational study found that, among patients with mildly to moderately affected digits, percutaneous needle aponeurotomy reduced contractures as effectively as limited fasciectomy does in clinical practice. Furthermore, percutaneous needle aponeurotomy provided a more rapid functional recovery and had a lower rate of mild complications.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Therapeutic, III.
Bilateral Facial Paralysis: A 13-Year Experience
Authors: Gaudin Robert A. , Jowett Nathan , Banks Caroline A. , Knox Christopher J. , Hadlock Tessa A. 
Published: June 2016

Background:
Bilateral facial palsy is a rare clinical entity caused by myriad disparate conditions requiring different treatment paradigms. Lyme disease, Guillain-Barré syndrome, and leukemia are several examples. In this article, the authors describe the cause, the initial diagnostic approach, and the management of long-term sequelae of bilateral paralysis that has evolved in the authors’ center over the past 13 years.

Methods:
A chart review was performed to identify all patients diagnosed with bilateral paralysis at the authors’ center between January of 2002 and January of 2015. Demographics, signs and symptoms, diagnosis, initial medical treatment, interventions for facial reanimation, and outcomes were reviewed.

Results:
Of the 2471 patients seen at the authors’ center, 68 patients (3 percent) with bilateral facial paralysis were identified. Ten patients (15 percent) presented with bilateral facial paralysis caused by Lyme disease, nine (13 percent) with Möbius syndrome, nine (13 percent) with neurofibromatosis type 2, five (7 percent) with bilateral facial palsy caused by brain tumor, four (6 percent) with Melkersson-Rosenthal syndrome, three (4 percent) with bilateral temporal bone fractures, two (3 percent) with Guillain-Barré syndrome, one (2 percent) with central nervous system lymphoma, one (2 percent) with human immunodeficiency virus infection, and 24 (35 percent) with presumed Bell palsy. Treatment included pharmacologic therapy, physical therapy, chemodenervation, and surgical interventions.

Conclusions:
Bilateral facial palsy is a rare medical condition, and treatment often requires a multidisciplinary approach. The authors outline diagnostic and therapeutic algorithms of a tertiary care center to provide clinicians with a systematic approach to managing these complicated patients.
Metal Artifact Reduction in Computed Tomography After Deep Brain Stimulation Electrode Placement Using Iterative Reconstructions
Authors: Aissa Joel , Boos Johannes , Schleich Christoph , Sedlmair Martin , Krzymyk Karl , Kröpil Patric , Antoch Gerald , Thomas Christoph 
Published: June 2016

Objectives
Diagnostic accuracy of intraoperative computed tomography (CT) after deep brain stimulation (DBS) electrode placement is limited due to artifacts induced by the metallic hardware, which can potentially mask intracranial postoperative complications. Different metal artifact reduction (MAR) techniques have been introduced to reduce artifacts from metal hardware in CT. The purpose of this study was to assess the impact of a novel iterative MAR technique on image quality and diagnostic performance in the follow-up of patients with DBS electrode implementation surgery.

Materials and Methods
Seventeen patients who had received routine intraoperative CT of the head after implantation of DBS electrodes between March 2015 and June 2015 were retrospectively included. Raw data of all patients were reconstructed with standard weighted filtered back projection (WFBP) and additionally with a novel iterative MAR algorithm. We quantified frequencies of density changes to assess quantitative artifact reduction. For evaluation of qualitative image quality, the visibility of numerous cerebral anatomic landmarks and the detectability of intracranial electrodes were scored according to a 4-point scale. Furthermore, artifact strength overall and adjacent to the electrodes was rated.

Results
Our results of quantitative artifact reduction showed that images reconstructed with iterative MAR (iMAR) contained significantly lower metal artifacts (overall low frequency values, 1608.6 ± 545.5; range, 375.5–3417.2) compared with the WFBP (overall low frequency values, 4487.3 ± 875.4; range, 2218.3–5783.5) reconstructed images (P < 0.004). Qualitative image analysis showed a significantly improved image quality for iMAR (overall anatomical landmarks, 2.49 ± 0.15; median, 3; range, 0–3; overall electrode characteristics, 2.35 ± 0.16; median, 2; range, 0–3; artifact characteristics, 2.16 ± 0.08; median, 2.5; range, 0–3) compared with WFBP (overall anatomical landmarks, 1.21 ± 0.64; median, 1; range, 0–3; overall electrode characteristics, 0.74 ± 0.37; median, 1; range, 0–2; artifact characteristics, 0.51 ± 0.15; median, 0.5; range, 0–2; P < 0.002).

Conclusions
Reconstructions of cranial CT images with the novel iMAR algorithm in patients after DBS implantation allows an efficient reduction of metal artifacts near DBS electrodes compared with WFBP reconstructions. We demonstrated an improvement of quantitative and qualitative image quality of iMAR compared with WFBP in patients with DBS electrodes.
mmgenome: a toolbox for reproducible genome extraction from metagenomes
Authors: Karst Søeren M. , Kirkegaard Rasmus H. , Albertsen Mads 
Published: June 2016

ABSTRACTSummaryRecovery of population genomes is becoming a standard analysis in metagenomics and a multitude of different approaches exists. However, the workflows are complex, requiring data generation, binning, validation and finishing to generate high quality population genome bins. In addition, several different approaches are often used on the same dataset as the optimal strategy to extract a specific population genome varies. Here we introduce mmgenome: a toolbox for reproducible genome extraction from metagenomes. At the core of mmgenome is an R package that facilitates effortless integration of different binning strategies by collecting information on scaffolds. Genome binning is facilitated through integrated tools that support effortless visualizations, validation and calculation of key statistics. Full reproducibility and transparency is obtained through Rmarkdown, whereby every step can be recreated.Availability and implementationThe binning framework of mmge-nome is implemented in R. Wrapper scripts for data generation and finishing is written in Perl. The mmgenome toolbox and associated step-by-step guides are available athttp://madsal-bertsen.github.io/mmgenome/.Contactma@bio.aau.dkSupplementary informationSupplementary data are available atBioinformaticsonline.
RNase reverses segment sequence in the anterior of a beetle egg (Callosobruchus maculatus, Coleoptera)
Authors: van der Meer Jitse M. 
Published: June 2016

AbstractThe genetic regulation of anterior-posterior segment pattern development has been elucidated in detail forDrosophila, but it is not canonical for insects. A surprising diversity of regulatory mechanisms is being uncovered not only between insect Orders, but also within the Order of the Diptera. This raises the question whether the same diversity of regulatory mechanisms exists within other insect Orders. This paper draws attention to the promise of the pea beetleCallosobruchus maculatusfor elucidating the evolution of pattern regulation mechanisms in Coleoptera and other insect Orders. Introduction of RNase in eggs ofCallosobruchusreplaces anterior segments with posterior segments oriented in mirror image symmetry to the original posterior segments (double abdomens). Reversal is specific for RNase activity, for treatment of the anterior egg pole and for cytoplasmic RNA. Yield depends on developmental stage, enzyme concentration and temperature. A maximum of 30% of treated eggs reversed segment sequence after puncture in 10.0 μg/ml RNase S reconstituted from S-protein and S-peptide at 30 °C. This result sets the stage for an analysis of the genetic regulation of segment pattern formation in the long germ embryo of the ColeopteranCallosobruchusand for comparison with the short germ embryo of the ColeopteranTribolium.
Understanding boundary effects and confocal optics enables quantitative FRAP analysis in the confined geometries of animal, plant, and fungal cells
Authors: Kingsley James L. , Bibeau Jeffrey P. , Mousavi S. Iman , Unsal Cem , Chen Zhilu , Huang Xinming , Vidali Luis , Tüzel Erkan 
Published: June 2016

AbstractFluorescence Recovery After Photobleaching (FRAP) is an important tool used by cell biologists to study the diffusion and binding kinetics of vesicles, proteins, and other molecules in the cytoplasm, nucleus or cell membrane. While many FRAP models have been developed over the past decades, the influence of the complex boundaries of three-dimensional cellular geometries on the recovery curves, in conjunction with ROI and optical effects (imaging, photobleaching, photoswitching, and scanning), has not been well studied. Here, we developed a three-dimensional computational model of the FRAP process that incorporates particle diffusion, cell boundary effects, and the optical properties of the scanning confocal microscope, and validated this model using the tip-growing cells ofPhyscomitrella patens. We then show how these cell boundary and optical effects confound the interpretation of FRAP recovery curves, including the number of dynamic states of a given fluorescent protein, in a wide range of cellular geometries-both in two and three dimensions-namely nuclei, filopodia, and lamellipodia of mammalian cells, and in cell types such as the budding yeast,S. pombe, and tip-growing plant cells. We explored the performance of existing analytical and algorithmic FRAP models in these various cellular geometries, and determined that the VCell VirtualFRAP tool provides the best accuracy to measure diffusion coefficients. Our computational model is not limited only to these cells types, but can easily be extended to other cellular geometries via the graphical Java-based application we also provide. This particle-based simulation-called the Digital Confocal Microscopy Suite, DCMS-can also perform fluorescence dynamics assays, such as Number and Brightness (N&B), Fluorescence Correlation Spectroscopy (FCS), Raster Image Correlation Spectroscopy (RICS), and could help shape the way these techniques are interpreted.
Purchasing of logistical services: a new view of LSPs’ proactive strategies
Authors: Fulconis François , Nollet Jean , Paché Gilles 
Published: June 2016

PurposeThe purpose of this viewpoint is to analyze the emergence of a modified equilibrium in the relationship between buyers (“shippers”) and suppliers (“providers”) of logistical services. In the 1990s, the logistical service providers (LSPs) had relatively little power and were often asked to perform basic operations. The situation has evolved as a result of proactive strategies implemented by some forward-thinking LSPs. In this viewpoint, the emphasis is on the strategies developed by shippers which the authors labeled the “ramp effect”.Design/methodology/approachThe authors discuss the impact of the ramp effect on LSPs’ innovation processes. This viewpoint is based on the authors’ experience in the field, on a literature review focused on the logistics industry and on the purchasing strategies applied to logistical services.FindingsThe authors show that the buyers of logistical services have lost some of their power because of two main factors: LSPs’ embeddedness in the shipper’s supply chain and the transformation of LSPs into orchestrators (labeled fourth-party logistics). This viewpoint discusses the relational disequilibrium between shippers and LSPs rather than the cooperative relationships between them.Originality/valueThe ramp effect as a source of innovation and proactive strategies for LSPs has never been covered in the management literature. This viewpoint provides both academics and practitioners with a different perspective of the relational disequilibrium between buyers and sellers of logistical services.
Reducing the cost of mental health problems at work – what can companies do?
Authors: Bishop Piers 
Published: June 2016

Purpose
The number of companies reporting mental health problems among staff is increasing. The author argues that initiatives to help staff cope with these difficulties are too late and that it is the duty of organizations to develop a workplace culture and environment where people can be motivated but calm and that other benefits will also flow from this.

Design/methodology/approach
The paper reports findings from the CIPD, HSE and NHS as background to a discussion of how auditing unmet human needs might be expected to improve mental health at work.

Findings
The paper suggests that a relatively simple and inexpensive approach could change the landscape of human emotion at work and that the process would embed a new culture of understanding and coaching in management.

Research limitations/implications
The conclusions would not necessarily extend to repetitive manufacturing processes and implementation would be difficult in organizations wedded to early twentieth century “scientific” management principles.

Practical implications
The paper has implications for organizations operating in the “knowledge” economy where the management has an interest in developing and retaining a happy and energized staff.

Social implications
The paper has implications for people whose lives are affected by stress generated by the working environment and culture.

Originality/value
This paper fits two identified needs: to suggest better ways of supporting staff who might develop mental health problems at work and to suggest a framework that will fill the gap left by the approaching demise of the annual review or appraisal process.
Establishing spirituality in the workplace
Authors: Wang Zhiqiang , Han Yong 
Published: June 2016

Purpose
Explores, from an insider’s perspective, human resource’s (HR’s) critical role in establishing spirituality practice at the Guangxi Institute of Public Administration, for enhancing academics and administrative staff’ intrinsic satisfaction.

Design/methodology/approach
Describes the various forms of spiritual human resource management (HRM) practice that the Guangxi Institute of Public Administration applied in the workplace.

Findings
Reports that various forms of spiritual HRM practice could improve the organizational productivity through employees’ engagement; for example, increased use of initiative, helping each other, making constructive suggestions for team work, reducing individuals level of workload and conflict resolution.

Practical Implications
Explains that HR managers could develop a highly committed and productive workplace through designing various forms of spiritual HRM practice, including connecting employees with nature by building natural featured campus and bringing in plants at workplace, encouraging employees to take exercise and/or breaks to develop their physical and spiritual wellness, celebrating important milestones and achievements, organizing informal teams to get to know each other better (hobbies, likes and dislikes), decorating office with employee-made art, acknowledging employees’ creative expression and promoting feelings of egalitarianism.

Originality/value
Offers interesting details of spiritual HRM practice, from an insider’s perspective, in a Chinese context.
The research motivation scale: validation with faculty from American schools of education
Authors: Leech Nancy L. , Haug Carolyn A. 
Published: June 2016

PurposeThis paper aims to compare the psychometric properties of the Research Motivation Scale (RMS) from faculty in schools of education in American research universities to previous findings on this scale when administered to science, technology, engineering and mathematics (STEM) faculty.Design/methodology/approachThis study was an exploratory, quantitative study using survey research methods, and utilizing confirmatory and exploratory factor analyses and statistical tests of population differences.FindingsResults indicate an adequate fit to a previously found three-factor structure. However, a new four-factor model, accounting for 47 per cent of the variance, was identified as a better fit: failure avoidance, intrinsic reward – satisfaction, intrinsic reward – joy and extrinsic reward. The overall reliability for the entire measure was 0.76. Intrinsic motivation and failure avoidance were rated statistically more important by education faculty than STEM faculty.Research limitations/implicationsAs an exploratory study and because of the chosen research approach, generalizations may be limited and further research in this area is recommended.Practical implicationsThis study contributes to the literature on RMS with data from education faculty. Results support conceptual frameworks regarding faculty outcomes and professional growth, and suggest ways faculty may be encouraged to increase research productivity.Social implicationsThis paper includes implications for societal support for research institutions by modeling factors that affect faculty motivations to produce research and thereby increase institutional productivity.Originality/valueThis study builds on conceptual frameworks, explores the use of the RMS with education faculty and compares faculty motivation to conduct research across disciplines.
Applying cultural capital and field to doctoral student socialization
Authors: Gopaul Bryan 
Published: June 2016

Purpose
Although the production of a dissertation and the transition to an independent researcher undergird the outcomes of doctoral education, this study aims to emphasize issues of inequality in doctoral study through the use of Bourdieu’s (1977, 1986) concepts of cultural capital and field.

Design/methodology/approach
This qualitative study with 15 doctoral students in Engineering and in Philosophy revealed that activities in doctoral study that tend to socialize students possess value, given the conventions of various contexts or social spaces related to academe.

Findings
Doctoral students who attain particular accomplishments experience doctoral study in ways that suggest that doctoral study is a system of conventions and norms that imbue particular activities with value, which then impact students’ doctoral education experiences.

Originality/value
Inequality is tied to students’ portfolio of achievements, as the value of these achievements suggests differential socialization experiences, such that different students learn about the norms and practices within doctoral study in different ways.
PhD prepared: research skill development across the undergraduate years
Authors: Willison John , Buisman-Pijlman Femke 
Published: June 2016

Purpose
Many countries are looking for ways to enable students to engage more effectively with PhD study. This paper aims to consider the effects of explicit discipline-specific research skill development embedded in multiple semesters of an undergraduate degree on PhD preparedness.

Design/methodology/approach
This case study of one Bachelor of Health Science programme determined the effectiveness of the implementation of a conceptual model, the Researcher Skill Development framework, across the undergraduate degree programme. Data were gathered through interviews of 9 academic staff and 14 students in their fourth year of undergraduate study, which is a research-focused year.

Findings
All students and academics stated the benefits of the use of the Researcher Skill Development framework in undergraduate study including: deepening metacognition of research processes; assisting students toward acting and thinking like researchers; and the research-capacity building of the school. While all academics and all but one student recommended that the framework be used early in the degree programme, a number of interviewees specified problems with the existing implementation of the framework.

Research limitations/implications
While the results are not generalisable, the approach is worth studying in other degree programme-wide contexts to determine its broader capacity to enable students to be more research ready for PhD study when compared to current practice.

Practical implications
When adapted to the context, whole-of-degree research skill development may enable developing countries to have more students and developed countries to better prepared students commencing PhD studies.

Originality/value
No studies currently provide results for explicit research skill development across a degree programme, or of the benefits of this approach for PhD preparation.