bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Unique Paired Retinal Vessels of the Gray Short‐Tailed Opossum (Monodelphis domestica) and Their Relationship to Astrocytes and Microglial Cells
Authors: McMenamin Paul G. , Golborne Cecilia Naranjo , Chen Xiangting , Wheaton Ben , Dando Samantha 
Published: April 2017

ABSTRACTIn marsupials that possess a retinal vasculature, the arterial and venous segments, down to the smallest calibre capillaries, have been shown to occur in pairs. This pattern is seen in the marsupial central nervous system (CNS) but not in other tissues in this group or in any tissues in eutherian mammals. The present study aimed to determine if the gray short‐tailed opossum (Monodelphis domestica), a south American marsupial, possesses double retinal vessels. Secondly, we investigated the relationship between vessels and astrocytes and microglia, which are known to play pivotal roles in the blood retinal barrier and immune surveillance respectively. Eyes from M. domestica between 2 months and 33 months of age were examined by bright field and fluorescein angiography, resin histology, and wholemount immunostaining. Retinal vessels in this marsupial always occur in closely related pairs with the arteriolar limb usually on the vitread aspect. Branches penetrate the retina to form layers of paired capillaries as far as the outer nuclear layer. Dense networks of GFAP+ astrocytes enveloped the vitread aspect of vessels. No particularly strong association with blood vessels and ramified Iba1+ and Ib4+ microglia was noted. M. domestica possessed the unusual paired vasculature and capillary loops arrangement previously described in the marsupial CNS. These observations in a small laboratory‐friendly marsupial open up new frontiers to investigate the factors that regulate paired blood vessel development and the functional significance of this arrangement when compared to the anastomotic pattern observed in the retina of eutherian mammals. Anat Rec, 300:1391–1400, 2017. © 2017 Wiley Periodicals, Inc.
Electronic Spectroscopy of Protonated 1‐Aminopyrene in a Cold Ion Trap
Authors: Noble Jennifer Anna , Dedonder‐Lardeux Claude , Mascetti Joëlle , Jouvet Christophe 
Published: April 2017

AbstractIn aromatic systems that contain an amino group, there is competition between protonation on a carbon atom of the skeleton and protonation on the amino group. Herein, we studied the photofragmentation of protonated 1‐aminopyrene in a cold ion trap and mainly observed the protonated amino tautomer, which led to fragmentation pathways through the loss of H or NH3 groups. Several excited states were assigned, among which the fourth excited state showed broadened bands, thus indicating a fast decay that was attributed to the presence of a πσ* charge‐transfer state by comparison of the experimental results with ab initio calculations. We deduced the πσ* transition energies in protonated aromatic amino compounds of increasing size directly from the ionization potentials of the neutral aromatic unsubstituted molecules. Tautomers that were protonated on a carbon atom of the pyrene skeleton were also weakly observed, and we showed that two tautomers that were protonated on a carbon atom of the aromatic ring could be distinguished by using electronic spectroscopy.
Study of the variability of Nova V5668 Sgr, based on high‐resolution spectroscopic monitoring
Authors: Jack D. , Robles Pérez J. de J. , De Gennaro Aquino I. , Schröder K.‐P. , Wolter U. , Eenens P. , Schmitt J. H. M. M. , Mittag M. , Hempelmann A. , González‐Pérez J. N. , Rauw G. , Hauschildt P. H. 
Published: April 2017

BackgroundWe present results of our dense spectroscopic monitoring of Nova V5668 Sgr.Materials and MethodsStarting on March 19, 2015, only a few days after its discovery, we have obtained a series of spectra with the Telescopio Internacional en Guanajuato, Robótico y Espectroscópico telescope and its Heidelberg extended range optical spectrograph échelle spectrograph, which offers a resolution of R = 20,000 and covers the optical wavelength range 3,8008,800 Å. We performed a line identification of the discernible features for four spectra, which are representative of the respective phases in the light curve evolution of that nova. We simultaneously analyzed the variations in the visual light curve and the corresponding spectra of Nova V5668 Sgr.ResultsWe found that, during the declining phases of the nova, the absorption features in all hydrogen and many other lines had shifted to higher expansion velocities of about ‐2,000 km s−1. Conversely, during the rise toward the following maximum, these observed absorption features had returned to lower expansion velocities. We found that the absorption features of some Fe II lines displayed the same behavior, but in addition disappeared for a few days during some declining phases. Features of several N I lines also disappeared, while new N II lines appeared in the emission for a few days during some of the declining phases of the light curve of Nova V5668 Sgr. The shape of the emission features is changing during the evolution, and shows a clear double‐peak structure after the deep minimum.ConclusionsThanks to the dense spectral monitoring we could observe several interesting developments of the Nova V5668 Sgr.
Optimizing coordinated transfer with probabilistic vehicle arrivals and passengers' walking time
Authors: Xiao Mei , Chien Steven , Hu Dawei 
Published: April 2017

SummarySupporting efficient connections by synchronizing vehicle arrival time and passengers' walking time at a transfer hub may significantly improve service quality, stimulate demand, and increase productivity. However, vehicle travel times and walking times in urban settings often varies spatially and temporally due to a variety of factors. Nevertheless, the reservation of slack time and/or the justification of vehicle arrival time at the hub may substantially increase the success of transfer coordination. To this end, this paper develops a model that considers probabilistic vehicle arrivals and passengers walking speeds so that the slack time and the scheduled bus arrival time can be optimized by minimizing the total system cost. A case study is conducted in which the developed model is applied to optimize the coordination of multiple bus routes connecting at a transfer station in Xi'an, China. The relationship between decision variables and model parameters, including the mean and the standard deviation of walking time, is explored. It was found that the joint impact of probabilistic vehicle arrivals and passengers' walking time significantly affects the efficiency of coordinated transfer. The established methodology can essentially be applied to any distribution of bus arrival and passenger walking time. Copyright © 2017 John Wiley & Sons, Ltd.
Modell zur numerischen Untersuchung der Trocknung in Estrichdämmschichten
Authors: Bianchi‐Janetti Michele , Gebauer Ralf , Ochs Fabian , Feist Wolfgang 
Published: April 2017

AbstractEstriche in Wohngebäuden werden im deutschsprachigen Raum überwiegend als Estriche auf Dämmschicht ausgeführt. Auf diese Estriche sind nur ausnahmsweise, zum Beispiel bei Nutzung als Feuchtraum, Abdichtungen eingebaut. Wurden die Estrichdämmschichten durch Wasserschäden durchfeuchtet, wird in der Regel durch technische Trocknung versucht, den ursprünglichen, trockenen Zustand wieder herzustellen. Die Trocknungsvorgänge wurden bislang empirisch beschrieben. Eine genaue Kenntnis der Vorgänge führt bislang zu Trocknungszeiten, mit welchen in der Regel eine vollständige Trocknung nicht erreicht wird. Durch Entwicklung eines Modells zur numerischen Simulation der Trocknungsvorgänge können künftig, unter Beachtung der hygrothermischen Ortsverhältnisse und abhängig vom eingebauten Dämmstoff, der Dämmstoffdicke und der gewählten Turbinenleistung, ausreichend lange Trocknungszeiten prognostiziert werden.
Vorhangfassade auf Holzbasis – Untersuchungen zum Schallschutz, Feuchteschutz und Brandschutz
Authors: Tywoniak Jan , Nováček Jiří , Hejtmánek Petr , Bureš Michal , Staněk Kamil , Lupíšek Antonín , Volf Martin 
Published: April 2017

AbstractDieser Beitrag befasst sich mit der Entwicklung einer Systemlösung für den Ersatz alter nichttragender Außenwände bei Nichtwohngebäuden aus den 1960er‐ und 1970er‐Jahren. Die Hauptidee war es dabei, ein vorfabriziertes Produkt zu entwickeln, das moderne Holzprodukte verwendet, um eine Alternative zu üblichen Metallbausystemen anzubieten. Es hat sich bestätigt, dass ohne detaillierte bauphysikalisch orientierte Analysen und Messungen eine erfolgreiche Entwicklung kaum möglich ist. Im ersten Teil in Bauphysik Heft 1/2017 wurden Konstruktion, Wärmeschutz und eine umweltorientierten Analyse behandelt. Der vorliegende Teil befasst sich mit den wichtigen bauphysikalischen Aspekten Bauakustik, Brandschutz und Feuchteschutz.
Die neue Siemens Konzernzentrale München – eines der nachhaltigsten Bürogebäude Europas
Authors: Berger Tobias , Schade André 
Published: April 2017

AbstractIm Frühjahr 2010 lobte die Siemens AG einen internationalen Wettbewerb für den Neubau ihrer Konzernzentrale am Standort Wittelsbacherplatz in München aus. Das Gebäude sollte 45 000 m2 oberirdische Geschossfläche für 1 200 Mitarbeiter bieten und dabei besonders nachhaltig und technisch innovativ sein. Aufgrund der prominenten Lage war es dem Bauherrn darüber hinaus auch sehr wichtig, ein nachhaltiges Gebäude mit modernen Arbeitswelten zu schaffen, das gleichzeitig öffentlich zugänglich sein sollte. Dabei sollte es sich um ein hochmodernes Gebäude handeln, das sich gleichermaßen in die sensible innenstädtische Lage einfügt. Der nachfolgende Bericht beschreibt die tragende Konstruktion des Gebäudes der Hauptverwaltung, die Integration der unter Denkmalschutz stehenden Gebäude am Wittelsbacher Platz sowie die Gebäudehülle.
CdSe and CdSe/CdS core–shell QDs: New approach for synthesis, investigating optical properties and application in pollutant degradation
Authors: Abbasi S. , Molaei M. , Karimipour M. 
Published: April 2017

AbstractIn this work, CdSe quantum dots (QDs) were synthesized by a simple and rapid microwave activated approach using CdSO4, Na2SeO3 as precursors and thioglycolic acid (TGA) as capping agent molecule. A novel photochemical approach was introduced for the growth of CdS QDs and this approach was used to grow a CdS shell around CdSe cores for the formation of a CdSe/CdS core–shell structure. The core–shells were structurally verified using X‐ray diffraction, transmission electron microscopy and FTIR (Fourier‐transform infrared (FTIR)) spectroscopy. The optical properties of the samples were examined by means of UV–Vis and photoluminescence (PL) spectroscopy. It was found that CdS QDs emit a broad band white luminescence between 400 to 700 nm with a peak located at about 510 nm. CdSe QDs emission contained a broad band resulting from trap states between 450 to 800 nm with a peak located at 600 nm. After CdS shell growth, trap states emission was considerably quenched and a near band edge emission was appeared about 480 nm. Optical studies revealed that the core–shell QDs possess strong ultraviolet (UV) − visible light photocatalytic activity. CdSe/CdS core–shell QDs, showed an enhancement in photodegradation of Methyl orange (MO) compared with CdSe QDs.
Evaluation of the peritoneal carcinomatosis index with CT and MRI
Authors: Dohan A , Hoeffel C , Soyer P , Jannot A S , Valette P-J , Thivolet A , Passot G , Glehen O , Rousset P 
Published: April 2017

Abstract

Background
The aim was to determine the incremental value of MRI compared with CT in the preoperative estimation of the peritoneal carcinomatosis index (PCI).

Methods
CT and MRI examinations of patients with peritoneal carcinomatosis were evaluated. CT images were first analysed by two observers who determined a first PCI (PCICT). Then, the two observers reviewed MRI examinations in combination with CT and determined a second PCI (PCICT+MRI). The sensitivity and negative predictive value of the two imaging sets were determined using surgery as a reference standard (PCIRef).

Results
CT plus MRI was more accurate in predicting the surgical PCI than CT alone. The absolute difference between PCICT+MRI and PCIRef was lower than that between PCICT and PCIRef (mean(s.d.) 3·96(4·10) versus 4·89(4·73); P = 0·010). The number of true-positive findings increased from 106 to 125 for reader 1 and from 117 to 132 for reader 2 with the adjunct of MRI. For both readers, an increased sensitivity was obtained when both MRI and CT were used (from 63 to 81 per cent for reader 1; from 44 to 81 per cent for reader 2). The increase in sensitivity was greater for patients with a moderate volume of disease.

Conclusion
The combination of CT and MRI improved the preoperative estimation of PCI compared with CT alone.
Analytical challenges in quantifying abiraterone with LC–MS/MS in human plasma
Authors: Benoist Guillemette E. , van der Meulen Eric , Lubberman Floor J.E. , Gerritsen Winald R. , Smilde Tineke J. , Schalken Jack A. , Beumer Jan H. , Burger David M. , van Erp Nielka P. 
Published: April 2017

AbstractA method was developed and validated to quantify abiraterone in human plasma. During assay development, several analytical challenges were encountered: limited stability in patient samples, adsorption to glass, coelution with metabolites and carry‐over issues. Limited stability (2 h) was found for abiraterone in fresh plasma as well as whole blood at ambient temperature. When kept at 2–8°C, abiraterone in plasma was stable for 24 h and in whole blood for 8 h. Adsorption of abiraterone to glass materials was addressed by using polypropylene throughout the method. Carry‐over was reduced to acceptable limits by incorporating a third mobile phase into the gradient. The chromatographic separation of abiraterone with its multiple metabolites was addressed by using a longer analytical column and adjusting the gradient. Abiraterone was extracted by protein precipitation, separated on a C18 column with gradient elution and analyzed with tandem quadrupole mass spectrometry in positive ion mode. A stable deuterated isotope was used as the internal standard. The assay ranges from 1 to 500 ng/mL. Within‐ and‐between‐day precisions and accuracies were below 13.4% and within 95–102%. This bioanalytical method was successfully validated and applied to determine plasma concentrations of abiraterone in clinical studies and in regular patient care for patients with metastatic castration‐resistant prostate cancer.
A meta‐analysis of functional magnetic resonance imaging studies of eye movements and visual word reading
Authors: Zhou Wei , Shu Hua 
Published: April 2017

AbstractIntroductionThe pattern of eye movements during reading is substantially correlated with linguistic factors. While there have been a large number of studies on the neural mechanisms of eye movements and word reading separately, a limited number of studies have compared the activation patterns of these two processes and discussed the associations of their corresponding brain regions within the framework of naturalistic reading.MethodsThis study conducted a meta‐analysis of the existing functional magnetic resonance imaging literature on prosaccades and visual word reading using the activation likelihood estimation algorithm.ResultsOur main finding was that, although prosaccades and word reading mainly activated dorsal and ventral brain areas, respectively, they both activated the left precentral gyrus (PreCG), left superior parietal lobe, right PreCG, right lingual gyrus, and bilateral medial frontal gyrus.ConclusionThese findings provide new insights into cognitive processes involved with naturalistic reading, which requires both eye movements and word reading.
Eco‐efficiency: GHG reduction related environmental and economic performance. The case of the companies participating in the EU Emissions Trading Scheme
Authors: Czerny Albert , Letmathe Peter 
Published: April 2017

AbstractEmpirical findings on eco‐efficiency are still inconsistent. Using survey data based on a sample of 283 European carbon‐intensive companies participating in the EU ETS between 2005 and 2012, this article investigates the causal relationships between the corporate environmental strategy focus, proactive GHG reductions and related environmental and economic performance, while taking into account an important contingent factor: the initial state of technology. The study's findings show that eco‐efficiency was generally not obvious among the companies during the first two trading periods. It furthermore indicates that GHG emissions were generally not reduced cost‐effectively, as companies' intrinsic values were more likely to have influenced carbon reduction related decisions to a greater degree than the economic incentives resulting from the market mechanisms of the ETS. The results not only shed light on firm behavior with regard to technology management but also provide insights for policy makers into how to stimulate more cost‐effective environmental investments. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
Baeyer–Villiger Oxidation of Cyclic Ketones by Using Tin–Silica Pillared Catalysts
Authors: Přech Jan , Carretero Marta Arroyo , Čejka Jiří 
Published: April 2017

AbstractThe Baeyer–Villiger oxidation is an important transformation of ketones into esters and particularly for cyclic ketones to lactones. We report here preparation and catalytic activity of layered Sn–silicate catalysts and mesoporous ordered silica catalysts in this reaction. Sn was introduced by using so‐called tin–silica pillaring or by impregnation with a mixture of tetraethylorthosilicate and tin(IV) alkoxide. The prepared catalysts were characterized by XRD, N2 physisorption, SEM, UV/Vis, and inductively coupled plasma optical emission spectroscopy (ICP‐OES) techniques and the catalysts were studied in the Baeyer–Villiger oxidation of cyclopentanone, norcamphor, and 2‐adamantanone with aqueous hydrogen peroxide. Norcamphor and 2‐adamantanone were oxidized easily with selectivity up to 99 %. Sn‐MS and IPC‐1‐SnPI materials exhibited the highest conversions (e.g., norcamphor: Sn‐MS 37 %, IPC‐1‐SnPI 36 % after 8 h vs. Sn‐MCM‐41 22 %). On the other hand, oxidation of cyclopentanone suffered from product hydrolysis to the corresponding 4‐hydroxybutanoic acid.
Enhanced Activity for Methanol Oxidation of Platinum Particles Supported on Iridium Oxide Modified Boron‐Doped Diamond Powder
Authors: Preda Loredana , Kondo Takeshi , Spataru Tanta , Marin Mariana , Radu Mihai , Osiceanu Petre , Fujishima Akira , Spataru Nicolae 
Published: April 2017

AbstractElectrocatalytic activity toward methanol oxidation in alkaline media of platinum nanoparticles supported on iridium oxide modified boron‐doped diamond powder (Pt/IrO2/BDDP) was assessed, and was compared with that of Pt deposited on bare diamond particles (Pt/BDDP). Cyclic voltammetry attests that the presence of the iridium oxide intermediary layer promotes methanol oxidation and provides a more efficient reactivation of Pt particles. Linear sweep voltammetric experiments performed in methanol‐free solution indicated that, at Pt/IrO2/BDDP, oxygen evolution is preceded by the formation, within the potential range of CH3OH oxidation, of adsorbed oxygenated species. As expected, the presence in close proximity of Pt particles of such species and of an important amount of IrOx(OH)y(evidenced by XPS) assists in the oxidative desorption of CO species adsorbed on Pt active sites. Steady‐state polarization measurements carried out in a floating configuration with Pt/IrO2/BDDP gas‐diffusion‐type electrodes yielded for methanol oxidation overall process Tafel slope values of ca. 120 mV decade−1, which compare well with those reported for traditional electrocatalysts.
Asymmetric Sequential Cu‐Catalyzed 1,6/1,4‐Conjugate Additions of Hard Nucleophiles to Cyclic Dienones: Determination of Absolute Configurations and Origins of Enantioselectivity
Authors: Blons Charlie , Morin Marie S. T. , Schmid Thibault E. , Vives Thomas , Colombel‐Rouen Sophie , Baslé Olivier , Reynaldo Thibault , Covington Cody L. , Halbert Stéphanie , Cuskelly Sean N. , Bernhardt Paul V. , Williams Craig M. , Crassous Jeanne , Polavarapu Prasad L. , Crévisy Christophe , Gérard Hélène , Mauduit Marc 
Published: April 2017

AbstractThe first stereocontrolled Cu‐catalyzed sequential 1,6/1,4‐asymmetric conjugate addition (ACA) of C‐metalated hard nucleophiles to cyclic dienones is reported. The use of DiPPAM (diphenylphosphinoazomethinylate) followed by a phosphoramidite as the stereoinducing ligands facilitated both high ee values for the 1,6‐ACA and high de values for the 1,4‐ACA reaction components, which thus gave enantioenriched 1,3‐dialkylated moieties. The absolute configurations were determined by using vibrational circular dichroism (VCD) and optical rotatory dispersion (ORD) spectroscopy, in combination with DFT calculations and X‐ray analysis. Interestingly, DFT calculations for the mechanism of enantioselective 1,6‐addition by using an unprecedented Cu–Zn bimetallic catalytic system confirmed this attribution. Lastly, exploring intramolecular cyclization avenues for enantioenriched 1,3‐dialkylated products provided access to the challenging drimane skeleton.
A comprehensive comparative analysis of treatment modalities for sinonasal malignancies
Authors: Robin Tyler P. , Jones Bernard L. , Gordon Oren M. , Phan Andy , Abbott Diana , McDermott Jessica D. , Goddard Julie A. , Raben David , Lanning Ryan M. , Karam Sana D. 
Published: April 2017

BACKGROUNDSinonasal malignancies are a rare and heterogeneous group of tumors for which there is a paucity of robust data with which to guide management decisions. The authors used the National Cancer Data Base to better understand the presenting characteristics of these tumors and to compare outcomes by treatment modality.METHODSThe National Cancer Data Base was queried for sinonasal malignancies diagnosed between 2004 and 2012. Overall survival was assessed using multivariate analyses and propensity score matching.RESULTSA total of 11,160 patients were identified for the initial analysis. The majority were male, aged 40 to 69 years, with tumors of the nasal cavity or maxillary sinus. Squamous cell histology was most common. The majority of patients presented with advanced tumor stage but without locoregional lymph node or distant metastases. Treatment modalities were compared for squamous cell carcinomas. In multivariate analysis, compared with surgery alone, patients who received adjuvant radiotherapy (hazard ratio [HR], 0.658 [P<.001]), adjuvant chemoradiotherapy (HR, 0.696 [P = .002]), or neoadjuvant therapy (HR, 0.656 [P = .007]) had improved overall survival. Patients who received radiotherapy alone (HR, 1.294 [P = .001]) or chemotherapy alone (HR, 1.834 [P<.001]) had worse outcomes. These findings were validated in propensity score matching. It is important to note that neoadjuvant chemoradiotherapy was associated with achieving a negative surgical margin (odds ratio, 2.641 [P = .045]).CONCLUSIONSSurgery is the mainstay of therapy for patients with sinonasal malignancies, but multimodality therapy is associated with improved overall survival. Cancer 2017;123:3040–49. © 2017 American Cancer Society.