bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compatibility of Kisin modules for different uniformizers
Authors: Liu Tong 
Published: January 2016

Abstract
Let p be a prime and T a lattice inside a semi-stable representation V. We prove that Kisin modules associated to T by selecting different uniformizers are isomorphic after tensoring a subring in

W
⁢

(
R
)

{W(R)}

. As consequences, we show that several lattices inside the filtered

(
φ
,
N
)

{(\varphi,N)}

-module of V constructed from Kisin modules are independent on the choice of uniformizers. Finally, we use a similar strategy to show that the Wach module can be recovered from the

(
φ
,

G
^

)

{(\varphi,\hat{G})}

-module associated to T when V is crystalline and the base field is unramified.
Successful treatment of placenta previa totalis using the combination of a two-stage cesarean operation and uterine arteries embolization in a hybrid operating room
Authors: Koyano Maya , Hasegawa Junichi , Arakaki Tatsuya , Matsuoka Ryu , Sekizawa Akihiko 
Published: January 2016

Abstract
A 37-year-old primigravida female with placenta previa totalis was transferred to our hospital at 29 weeks of gestation. A transvaginal ultrasound examination showed a dropped placenta into the uterine cervix and an effaced lower uterine segment. The boundary between the cervical muscle layer and the placenta was unclear. Consequently, although it was unclear whether complication of the adherence of placenta was present or not, massive hemorrhage with atonic bleeding in the lower uterine segment after placenta removal was strongly suspected. As the patient had uncontrolled vaginal bleeding, an emergency cesarean section was performed in a hybrid operating room. A transverse fundal incision of the uterus was made, and a 1143 g healthy neonate was delivered. As no signs of placental detachment or persistent bleeding were found, the uterus was closed, leaving the placenta. Thereafter bilateral uterine arterial embolization (UAE) with absorbable gelatin sponges was performed. On the third day after the operation, a second operation for placental removal. The placenta detached smoothly, but compression sutures were placed to control the bleeding at the site of placental removal around the uterine isthmus. In this case, we were able to conduct the treatment smoothly because of the antenatal ultrasound assessment and precise preparation of the cesarean section with UAE in the hybrid operation room. Using the hybrid operation room, sharing detailed surgical planning in cooperation with the physicians from other departments is important for obtaining a good outcome.
Intelligent drug delivery systems for the treatment of solid tumors
Authors: Stylianopoulos Triantafyllos 
Published: January 2016

AbstractThe rationale for the use of nanoparticle formulations to treat cancer is based on the ability of these particles to facilitate selective delivery of drugs to the tumor site, reducing adverse effects and improving therapeutic outcomes. Current clinically approved nanomedicines have managed to reduce adverse effects significantly but the increase in overall survival is modest in many cases. Therefore, even though the goal of a better quality of life for the cancer patients has been achieved in large part, the increase in life expectancy still remains a critical challenge. Abnormalities in the tumor micro-environment prevent homogeneous distribution of nanoparticles to the interior of the tumor, decreasing the efficacy of the drug. Intelligent drug delivery systems offer new hope for overcoming these physiological barriers posed by the tumor and have the potential to provide more effective treatments. This review discusses the barriers to the delivery of nanomedicines to solid tumors, suggests design considerations that could optimize delivery and reviews promising intelligent drug delivery systems that have been developed to date.
Intelligent Systems for Stabilizing Mode-Locked Lasers and Frequency Combs: Machine Learning and Equation-Free Control Paradigms for Self-Tuning Optics
Authors: Kutz J. Nathan , Brunton Steven L. 
Published: January 2016

Abstract
We demonstrate that a software architecture using innovations in machine learning
and adaptive control provides an ideal integration platform for self-tuning
optics. For mode-locked lasers, commercially available optical telecom
components can be integrated with servocontrollers to enact a training and
execution software module capable of self-tuning the laser cavity even in the
presence of mechanical and/or environmental perturbations, thus potentially
stabilizing a frequency comb. The algorithm training stage uses an exhaustive
search of parameter space to discover best regions of performance for one or
more objective functions of interest. The execution stage first uses a sparse
sensing procedure to recognize the parameter space before quickly moving to the
near optimal solution and maintaining it using the extremum seeking control
protocol. The method is robust and equationfree, thus requiring no detailed or
quantitatively accurate model of the physics. It can also be executed on a broad
range of problems provided only that suitable objective functions can be found
and experimentally measured.
Novel droplet near-field transducer for heat-assisted magnetic recording
Authors: Gosciniak Jacek , Mooney Marcus , Gubbins Mark , Corbett Brian 
Published: January 2016

Abstract
Two main ingredients of plasmonics are surface plasmon polaritons (SPP) and
localized surface plasmon resonances (LSPR) as they provide a high degree of
concentration of electromagnetic fields in the vicinity of metal surfaces, which
is well beyond that allowed by the diffraction limit of optics. Those properties
have been used in the new technique of heat assisted magnetic recording (HAMR)
to overcome an existing limit of conventional magnetic recording by utilizing a
near-field transducer (NFT). The NFT designs are based on excitation of surface
plasmons on a metal structure, which re-radiate with a subdiffraction limited
light spot confined in the near field. In this paper, we propose a novel
“droplet”-shaped NFT, which takes full advantage of a recenltly proposed
Mach–Zehnder Interferometer (MZI), a coupling arrangement that allows optimal
coupling of light to the transducer. The droplet design ensures better impedance
match with the recording media and, consequently, better coupling of power. The
droplet design results in very high enhancement of the electric field and allows
the confinement of light in a spot size much smaller than the present stateof-
the-art lollipop transducer.
Crystal structure of (2,5-dihydroxyphenyl)-(4-methoxyphenyl)methanone, C14H12O4
Authors: Benites Julio , Valderrama Jaime A. , Ríos David , Cárdenas Alejandro , Brito Iván 
Published: January 2016

Abstract
C14H12O4, orthorhombic, Pca21 (no. 29), a = 22.6015(12) Å, b = 7.1344(4) Å, c = 7.3789(4) Å, V = 1189.83(11) Å3, Z = 4, R
gt
(F) = 0.065, wR
ref
(F
2
) = 0.186, T = 298 K.
Crystal structure of (E)-2,4-dibromo-6-(((2-nitrophenyl)imino)methyl)phenol, C13H8Br2N2O3
Authors: Hong Yong , Huang Dushu , Liu Wei , Zhang Yinghong 
Published: January 2016

Abstract
C13H8Br2N2O3, monoclinic, P21/c (no. 14), a = 12.794(3) Å, b = 7.2041(15) Å, c = 14.862(3) Å, β = 93.355(5)°, V = 1367.5(5) Å3, Z = 4, R
gt
(F) = 0.0398, wR
ref
(F
2
) = 0.0938, T = 293 K.
Levofloxacin loaded gelrite-cellulose polymer based sustained ocular drug delivery: formulation, optimization and biological study
Authors: Aslam Mohammed , Imam Syed Sarim , Aqil Mohammed , Sultana Yasmin , Ali Asgar 
Published: January 2016

Abstract
In the present work, levofloxacin in situ gel formulation was developed using gelrite as a gelling agent in combination with hydroxy propyl methyl cellulose. The developed formulations were evaluated for physicochemical parameters, in vitro release, ex vivo transcorneal study, sterility testing, antimicrobial efficacy, ocular irritation study, histopathological and stability evaluation. The in vitro drug release study showed the extended drug release up to 12 h, and the best fit kinetic model was found to be Peppas model (R
2=0.9654), suggesting a Fickian diffusion process. The developed formulations showed optimized physicochemical results for all parameters. The optimized formulation showed therapeutically efficacious antimicrobial activity. Hens egg test-chorioallantoin membrane assay (HET-CAM) showed a mean score of 0.33 up to 24 h, which indicated the non-irritant property of the developed formulation. This non-irritant and stable in situ gel formulation of levofloxacin was found to be promising and safe for use as ocular delivery. The degradation rate constant and shelf life of developed optimized formulation (F14) were found to be low (1.213×10-4 at 25°C) and 2.14 years, respectively. This renders them favorable for ocular use as they would gel once in contact with the tear fluid, thus reducing nasolacrimal drainage, but would thin upon shearing, preventing ocular irritation and therefore induced lacrimation.
Effects of fiber surface modification on the friction coefficient of luffa fiber/polyester composites under dry sliding condition
Authors: Kalusuraman G. , Siva I. , Jappes J.T. Winowlin , Kumar S. Anand 
Published: January 2016

Abstract
In this study, the fiber extracted from the fruit of a luffa plant was used as a reinforcement to an unsaturated polyester resin matrix under two different fiber conditions. The untreated and alkali-treated fibers were impregnated and pressed to produce laminates. Composites were made with an optimal compression pressure of 5 MPa for 12 h of curing at room temperature. Ejected samples were cut according to the dimensions specified by the ASTM test specifications. To investigate the effects of fiber surface treatment on the frictional behavior of the produced composites under dry sliding wear conditions, wear test was conducted in a pin-on-disc equipment as per ASTM G99 at varying sliding velocities. In addition, hardness and un-notched impact strengths were measured and discussed. Results showed that the change in fiber surface morphology significantly changed the coefficient of friction of the composites. Moreover, the sliding distance had a prominent influence in increasing the friction between the composite and the counter face.
Improved fluorimetric measurement of uranium uptake and distribution in spring wheat (Triticum aestivum L.)
Authors: Borcia Cătălin , Popa Karin , Cecal Alexandru , Murariu Manuela 
Published: January 2016

Abstract
Uranium uptake and (radio)toxicity was tested on spring wheat (Triticum aestivum L.) in a laboratory study using differently
concentrated uranium nitrate solutions. Within these experiments, two analytical assays of uranium were comparatively tested: a fast
and improved fluorimetric assay and the classical colorimetric (U(IV)–arsenazo(III) complexation) one. During the germination, the
wheat seeds and plantlets supported well the uranium solutions of treatment within the entire concentration range
(1E-4–5E-3 M). Uranium proved to be non (radio)toxic to wheat as compared with other natural and anthropogenic
radiocations, probably because its uptake by spring wheat during the germination is low. Indeed, only a small fraction of uranium
administered was located within the roots, whereas the uranium content of the stems was negligible. A high correlation between the
results obtained by two analytical methods was found. However, the fluorimetric assay proved to be more reliable and fast, and
accurate.
The mental time travel continuum: on the architecture, capacity, versatility and extension of the mental bridge into the past and future
Authors: Breeden Prescott , Dere Dorothea , Zlomuzica Armin , Dere Ekrem 
Published: January 2016

Abstract
Mental time travel (MTT) is the ability to remember past events and to anticipate or imagine events in the future. MTT globally serves to optimize decision-making processes, improve problem-solving capabilities and prepare for future needs. MTT is also essential in providing our concept of self, which includes knowledge of our personality, our strengths and weaknesses, as well as our preferences and aversions. We will give an overview in which ways the capacity of animals to perform MTT is different from humans. Based on the existing literature, we conclude that MTT might represent a quantitative rather than qualitative entity with a continuum of MTT capacities in both humans and nonhuman animals. Given its high complexity, MTT requires a large processing capacity in order to integrate multimodal stimuli during the reconstruction of past and/or future events. We suggest that these operations depend on a highly specialized working memory subsystem, ‘the MTT platform’, which might represent a necessary additional component in the multi-component working memory model by Alan Baddeley.
Research on trajectory planning of non-developable surface for automated tape placement processing of composite
Authors: Liu Lin , Xiao Jun , Li Yong 
Published: January 2016

Abstract
Tape placement manufacturing process, as one of the automated forming technologies for composite material, not only substantially improves the productivity of composite component and reduces the cost of production significantly but also raises the reliability and stability of composite structure. Automated tape placement technology is mainly applied for manufacturing the fuselage and wing panel of airplane characterized by small curvature and large size. For these kinds of structural components with a non-developable surface, trajectory planning by “natural path” method could reduce the internal stress and improve the quality of composite products to a certain extent but not be optimized by quantitative characterization. On the basis of preliminary work, the theoretical model of “unnatural degree” (UD) is introduced in the first step, which could characterize the tensile and shear strain of the laying tape quantitatively. Secondly, by adjusting the iterative step and laying direction to diminish the UD, local stress could be softened in order to optimize the laying track. Ultimately, the simulation model of the non-developable surface is established under the Matlab software environment, and the “variable step-angle” algorithm is adopted to verify the adjustment effect of the tape-laying track.
Numerical Investigation of Transient Flow in a Prototype Centrifugal Pump during Startup Period
Authors: Zhang Yu-Liang , Zhu Zu-Chao , Dou Hua-Shu , Cui Bao-Ling , Li Yi , Zhou Zhao-Zhong 
Published: January 2016

AbstractTransient performance of pumps during transient operating periods, such as startup and stopping, has drawn more and more attentions recently due to the growing engineering needs. During the startup period of a pump, the performance parameters such as the flow rate and head would vary significantly in a broad range. Therefore, it is very difficult to accurately specify the unsteady boundary conditions for a pump alone to solve the transient flow in the absence of experimental results. The closed-loop pipe system including a centrifugal pump is built to accomplish the self-coupling calculation. The three-dimensional unsteady incompressible viscous flow inside the passage of the pump during startup period is numerically simulated using the dynamic mesh method. Simulation results show that there are tiny fluctuations in the flow rate even under stable operating conditions and this can be attributed to influence of the rotor–stator interaction. At the very beginning of the startup, the rising speed of the flow rate is lower than that of the rotational speed. It is also found that it is not suitable to predict the transient performance of pumps using the calculation method of quasi-steady flow, especially at the earlier period of the startup.
Evaluation of astrocytoma cell proliferation using diffusion-weighted imaging: correlation with expression of proliferating cell nuclear antigen
Authors: Zhang Kai , Li Chuanfu , Liu Ying , Li Li , Meng Xiangshui , Feng Dechao , Ma Xiangxing 
Published: January 2016

Abstract
The purpose of this study was to analyze if there is a significant correlation between the results of diffusionweighted
imaging (DWI) and the expression of proliferating cell nuclear antigen (PCNA) in astrocytomas. The
DWI scans of 19 different-grade astrocytomas were obtained on a 3 T magnetic resonance scanner. The average
regional apparent diffusion coefficients (ADC) were measured. The positive expression of PCNA was determined
immunohistochemically by using streptavidin-peroxidase complex staining, and was quantified by calculating its
calibrated opacity density (COD) using an image analysis system. The average regional ADC and PCNA COD of low
grade and high grade astrocytomas were compared. Correlations between regional ADC and PCNA COD were
analyzed. The average regional ADC of high grade astrocytomas was significantly (t = 10.169, P = 0.000) less (0.687
± 0.225 x 10-3 mm2/s) than that of low grade astrocytomas (1.572 ± 0.333 x 10-3 mm2/s). The PCNA COD (0.343 ±
0.052) of high grade astrocytomas was significantly (t=-7.858, P=0.000) greater than that (0.194 ± 0.012) of low
grade astrocytomas. There were strong negative correlations between regional ADC and PCNA COD (r = -0.801,
P = 0.000). The results demonstrated that DWI is helpful in evaluating cell proliferation and preoperatively grading
astrocytomas by measuring regional ADC.
Investigations of the EPR Parameters and Local Lattice Structure for the Rhombic Cu2+ Centre in TZSH Crystal
Authors: Li Chao-Ying , Liu Shi-Fei , Fu Jin-Xian 
Published: January 2016

Abstract
The electron paramagnetic resonance (EPR) parameters [i.e. g factors g

i
(i=x, y, z) and hyperfine structure constants A

i
] and the local lattice structure for the Cu2+ centre in Tl2Zn(SO4)2·6H2O (TZSH) crystal were theoretically investigated by utilising the perturbation formulae of these parameters for a 3d9 ion under rhombically elongated octahedra. In the calculations, the admixture of d orbitals in the ground state and the ligand orbital and spin-orbit coupling interactions are taken into account based on the cluster approach. The theoretical EPR parameters show good agreement with the observed values, and the Cu2+–H2O bond lengths are obtained as follows: R

x
≈1.98 Å, R

y
≈2.09 Å, R

z
≈2.32 Å. The results are discussed.
First Principle Investigation of (Bi2O3)
n
Clusters With n = 6 − 9
Authors: Geudtner Gerald , Calaminici Patrizia , Köster Andreas M. 
Published: January 2016

Abstract
Ground state and low lying isomer structures of (Bi2O3)
n
clusters with
n = 6 − 9 were determined by first-principle calculations. These calculations were performed
with the LCGTO-ADFT method as implemented in the deMon2k program. Initial structures from
Born–Oppenheimer molecular dynamics trajectories were selected as starting points for local
geometry optimizations. The optimized structures where identified as minimum structures by
frequency analysis. Furthermore, the structural relation between the clusters is
presented. This work shows for the (Bi2O3)8 cluster a higher stability then
for the other clusters.
Structure of Glassy Ag–Ge–Se by Neutron Diffraction with Isotope Substitution
Authors: Zeidler Anita , Salmon Philip Stephen , Piarristeguy Andrea , Pradel Annie , Fischer Henry Edward 
Published: January 2016

Abstract
The structure of glassy Ag0.077Ge0.212Se0.711, which
lies at y = 0.077 on the
Ag
y
(Ge0.23Se0.77)1−y
tie-line,
was investigated by using the method of neutron diffraction with
silver isotope substitution. Two glass transition temperatures were
found from a characterisation of the material using modulated
differential scanning calorimetry, which indicates a mixed phase
material. The diffraction method provides site-specific information on
the Ag coordination environment, and gives an average of
3.5(1) Ag–Se nearest-neighbours with a bond distance
of 2.65(1) Å together with 0.9(1)
Ag–Ag next nearest-neighbours at a distance of
2.9(2) Å. The incorporation of silver does not
appear to have a marked effect on the coordination number of Se
to other matrix (Ge or Se) atoms, which supports the
notion that Ag forms dative bonds with Se lone-pair
electrons. A model is given for predicting the change in the Se
to matrix atom coordination number when a monovalent metal such as
Ag is added to a Se rich Ge–Se base
glass.
In VivoMRI Mapping of Brain Iron Deposition across the Adult Lifespan
Authors: Acosta-Cabronero Julio , Betts Matthew J. , Cardenas-Blanco Arturo , Yang Shan , Nestor Peter J. 
Published: January 2016

Disruption of iron homeostasis as a consequence of aging is thought to cause iron levels to increase, potentially promoting oxidative cellular damage. Therefore, understanding how this process evolves through the lifespan could offer insights into both the aging process and the development of aging-related neurodegenerative brain diseases. This work aimed to map,in vivofor the first time with an unbiased whole-brain approach, age-related iron changes using quantitative susceptibility mapping (QSM)—a new postprocessed MRI contrast mechanism. To this end, a full QSM standardization routine was devised and a cohort ofN= 116 healthy adults (20–79 years of age) was studied. The whole-brain and ROI analyses confirmed that the propensity of brain cells to accumulate excessive iron as a function of aging largely depends on their exact anatomical location. Whereas only patchy signs of iron scavenging were observed in white matter, strong, bilateral, and confluent QSM–age associations were identified in several deep-brain nuclei—chiefly the striatum and midbrain—and across motor, premotor, posterior insular, superior prefrontal, and cerebellar cortices. The validity of QSM as a suitablein vivoimaging technique with which to monitor iron dysregulation in the human brain was demonstrated by confirming age-related increases in several subcortical nuclei that are known to accumulate iron with age. The study indicated that, in addition to these structures, there is a predilection for iron accumulation in the frontal lobes, which when combined with the subcortical findings, suggests that iron accumulation with age predominantly affects brain regions concerned with motor/output functions.SIGNIFICANCE STATEMENTThis study used a whole-brain imaging approach known as quantitative susceptibility mapping (QSM) to provide a novel insight into iron accumulation in the brain across the adult lifespan. Validity of the method was demonstrated by showing concordance with ROI analysis and prior knowledge of iron accumulation in subcortical nuclei. We discovered that, beyond these regions, there is extensive involvement of the frontal lobes that has been missed by past ROI analyses. Broadly speaking, therefore, the motor system selectively accumulates iron with age. The results offer insights into the aging process, but also offer a new approach to studying the role of iron dysregulation in the evolution of age-related neurodegenerative diseases.