bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface and Antimicrobial Activity of Sulfobetaines
Authors: Wieczorek Daria , Gwiazdowska Daniela , Staszak Katarzyna , Chen Ying‐Lien , Shen Tang‐Long 
Published: May 2016

AbstractSulfobetaines belong to the group of zwitterionic surfactants. They are electroneutral salts, which have in the same molecule, two ionic centers with different charge. Due to the specific structure they exhibit excellent properties such as good solubility in water and detergency. In this paper we present surface properties and adsorption parameters of sulfobetaines in water/air systems. From the adsorption isotherms the CMC value, the surface tension and surface pressure at the CMC as well as the efficiency of adsorption were determined. Physicochemical analyses of the data allowed for the further description of adsorption process. Results showed that sulfobetaines exhibit good surface properties especially low CMC and p20 values. Additionally the antimicrobial activity of sulfobetaines solutions against gram‐positive and gram‐negative bacteria were tested by the well‐diffusion method. MIC values and growth kinetics were determined by microdilution method. Antimicrobial assays demonstrated that sulfobetaines can be good antibacterial agents, but the activity of surfactants strongly depends on alkyl chain length.
Improved Butanol–Methanol (BUME) Method by Replacing Acetic Acid for Lipid Extraction of Biological Samples
Authors: Cruz Mutya , Wang Miao , Frisch‐Daiello Jessica , Han Xianlin 
Published: May 2016

AbstractExtraction of lipids from biological samples is a critical step in lipidomics, especially for shotgun lipidomics where lipid extracts are directly infused into a mass spectrometer. The butanol–methanol (BUME) extraction method was originally developed to extract lipids from plasma samples with 1 % acetic acid. Considering some lipids are sensitive to acidic environments, we modified this protocol by replacing acetic acid with lithium chloride solution and extended the modified extraction to tissue samples. Although no significant reduction of plasmalogen levels in the acidic BUME extracts of rat heart samples was found, the modified method was established to extract various tissue samples, including rat liver, heart, and plasma. Essentially identical profiles of the majority of lipid classes were obtained from the extracts of the modified BUME and traditional Bligh–Dyer methods. However, it was found that neither the original, nor the modified BUME method was suitable for 4‐hydroxyalkenal species measurement in biological samples.
Bioactive Compounds of Portuguese Virgin Olive Oils Discriminate Cultivar and Ripening Stage
Authors: Peres Fátima , Martins Luisa L. , Mourato Miguel , Vitorino Conceição , Ferreira‐Dias Suzana 
Published: May 2016

AbstractThe presence of different bioactive compounds in virgin olive oil affects its nutritional, oxidative and sensorial properties. Phenolic compounds are olive endogenous bioactive compounds highly susceptible to degradation. Olive endogenous oxidoreductases, mainly polyphenol oxidases (PPO) and peroxidases (POD), may play an important role on the profile of bioactive compounds in olive oil by promoting oxidation of phenolic compounds. The aim of this study was to evaluate if changes on PPO and POD activities in olive fruits from two Portuguese cultivars (Olea europaea, cv ‘Cobrançosa’ and cv ‘Galega Vulgar’) are related with the composition of their olive oils, especially phenolic compounds. Pattern recognition techniques [principal component analysis (PCA), cluster analysis (CA), and discriminant analysis (DA)] were used for multivariate data analysis. Olive oils characterized by their FA composition were grouped by cultivar. When olive oils were characterized by their phenolic composition, green pigments, and enzymatic activities in fruits, they could be discriminated by olive ripening stage. Along ripening, PPO activity was only detected in the fruit mesocarp of both cultivars and POD activity was mainly detected in the seeds. The POD activity, as well as vanillin and gamma‐tocopherol contents in olive oil increased with the ripening index. Conversely, higher PPO activity in fruits at early ripening stages together with higher levels of total phenols, green pigments, beta‐tocopherol, hydroxytyrosol and p‐coumaric acid in olive oils were observed. The ripening stage of fruits showed to be a key factor on the amount and profile of bioactive compounds of olive oil.
Variation in Seed Oil Content and Fatty Acid Composition of Globe Artichoke Under Different Irrigation Regimes
Authors: Nouraei Sina , Rahimmalek Mehdi , Saeidi Ghodratollah , Bahreininejad Babak 
Published: May 2016

AbstractSeed oil content of globe artichoke and its composition were assessed under three irrigation regimes, including irrigation at 20, 50, and 80 % depletion of soil available water. Water deficit affected the phenological characteristics, amount and the quality of the oil as well as the phenolics and antioxidant activity of the leaves and capitula. The seed oil content ranged from 18.7 % in 80 % to 22.8 % in 20 % treatment. The fatty acid composition of oil was determined using gas chromatography (GC). The predominant fatty acids in the oil were linoleic (51.68 %), oleic (34.22 %), palmitic (9.94 %), and stearic (3.58 %). Water deficit leads to reduced oil content, linoleic acid, the unsaturated/saturated fatty acid ratio and the iodine value. On the other hand, some other fatty acids such as palmitic and oleic acid and also the ratio of oleic/linoleic acid were elevated due to water deficit. Higher antioxidant activity was observed in capitula (IC50 = 222.6 μg ml−1) in comparison to the leaves (IC50 = 285.8 μg ml−1). Finally, the severe drought stress condition caused to gain higher oil stability, while the highest seed oil content and unsaturated fatty acids in the oil was obtained in non‐stress condition. Moreover, high phenolics, flavonoids and antioxidant activity as well as appreciable dry matter content were obtained in the moderate water stress condition.
Exploring cognitive integration of basic science and its effect on diagnostic reasoning in novices
Authors: Lisk Kristina , Agur Anne M. R. , Woods Nicole N. 
Published: May 2016

Integration of basic and clinical science knowledge is increasingly being recognized as important for practice in the health professions. The concept of ‘cognitive integration’ places emphasis on the value of basic science in providing critical connections to clinical signs and symptoms while accounting for the fact that clinicians may not spontaneously articulate their use of basic science knowledge in clinical reasoning. In this study we used a diagnostic justification test to explore the impact of integrated basic science instruction on novices’ diagnostic reasoning process. Participants were allocated to an integrated basic science or clinical science training group. The integrated basic science group was taught the clinical features along with the underlying causal mechanisms of four musculoskeletal pathologies while the clinical science group was taught only the clinical features. Participants completed a diagnostic accuracy test immediately after initial learning, and one week later a diagnostic accuracy and justification test. The results showed that novices who learned the integrated causal mechanisms had superior diagnostic accuracy and better understanding of the relative importance of key clinical features. These findings further our understanding of cognitive integration by providing evidence of the specific changes in clinical reasoning when basic and clinical sciences are integrated during learning.
Reducing length of stay and satisfying learner needs
Authors: Shepherd Lisa , Chahine Saad , Klingel Michelle , Zibrowski Elaine , Meiwald Allison , Lingard Lorelei 
Published: May 2016

A complicated relationship exists between emergency department (ED) learner needs and patient flow with solutions to one issue often negatively affecting the other. Teaching shifts that allow clinical teachers and learners to interact without the pressure of patient care may offer a mutually beneficial solution. This study investigated the relationship between teaching shifts on ED length of stay, student self-efficacy and knowledge application.
In 2012–2013, a prospective, cohort study was undertaken in a large Canadian acute-care teaching centre. All 132 clinical clerks completing their mandatory two-week emergency medicine rotation participated in three teaching shifts supervised by one faculty member without patient care responsibilities. The curriculum emphasized advanced clinical skills and included low fidelity simulation exercises, a suturing lab, image interpretation modules and discussion about psychosocial issues in emergency medicine. The clerks then completed seven clinical shifts in the traditional manner caring for patients under the supervision of an ED attending physician. Length of stay was compared during and one week following teaching shifts. A self-efficacy questionnaire was validated through exploratory factor analysis. Pre/post knowledge application was assessed using a paper-based clinical case activity.
Across 40.998 patient visits, median length of stay was shortened overall by 5 minutes (95 % CI:1.2, 8.8) when clerks were involved in their teaching shifts. In the first academic block, median length of stay was reduced by 20 minutes per patient (95 % CI:12.7, 27.3).
Actividad física y adaptación escolar en estudiantes de medicina en un campus de la Universidad Nacional Autónoma de México
Authors: Ríos Bustos Mercedes Esmirna , Torres Vaca Marisela , De la Torre Concepción 
Published: May 2016

Introducción: El ingreso a un plantel escolar implica un proceso de adaptación con repercusión en el rendimiento escolar y la convivencia. La formación integral y los estilos de vida saludables son aspectos actuales en los programas académicos. El incremento del trastorno de adaptación entre la población estudiantil de la Facultad de Estudios Superiores Zaragoza, UNAM, con su consecuencia: la depresión y el riesgo cada vez mayor de suicidio, fue el motivo para realizar esta investigación en función de la prevención del trastorno de adaptación.
Objetivo: Conocer la diferencia en la adaptación escolar en un grupo de estudiantes de nuevo ingreso que realizó actividad física durante el ciclo escolar y un grupo de estudiantes que no la realizaron.
Método: A dos grupos de 53 estudiantes cada uno, les fue aplicado un cuestionario escala Likert con 9 tópicos relacionados con adaptación escolar, uno de los grupos realizó actividad física durante el ciclo escolar mientras el otro grupo no la realizó. Se llevó a cabo un análisis intragrupo antes y después del estudio; un análisis cualitativo para los comentarios plasmados en los cuestionarios aplicados y una comparación cuantitativa ordinal con aplicación de chi cuadrado para la significación estadística.
Resultados: Cualitativamente se encontró una mejor adaptación entre los estudiantes que realizaron actividad física a lo largo del año escolar. En los resultados cuantitativos se encontró que el grupo estudio tuvo cambio significativo solo en el tópico: «satisfacción del plantel» (chi cuadrado 0.046). El grupo control tuvo cambio significativo en 2 tópicos: «satisfacción del plantel» y «expectativa de la carrera»: 0.025 y 0.020 respectivamente). Los parámetros restantes no sufrieron cambios significativos.
Conclusión: La actividad física constante favorece la mejor adaptación entre los estudiantes de nuevo ingreso, con ello se puede prevenir la depresión y su grave complicación: el suicidio.
Predictions for the northern coast of the shear rheology map: XXLAOS
Authors: Ewoldt Randy H. 
Published: May 2016

A new paradigm of rheological characterization, oscillatory simple shear with infinite forcing amplitudes, is introduced by Khair (J. Fluid Mech., vol. 791, 2016, R5). This pushes the technique of large-amplitude oscillatory shear (LAOS) to have two extremely large amplitudes (both strain-rate and strain), which we might call XXLAOS. Model-specific analytical predictions are derived for a suspension of nearly spherical rigid particles subject to Brownian rotational diffusion. The work illuminates a new regime of rheological characterization that may serve as a distinct proving ground for constitutive model selection and for probing the flow physics of rheologically complex fluids.
Simulation of convection at a vertical ice face dissolving into saline water
Authors: Gayen Bishakhdatta , Griffiths Ross W. , Kerr Ross C. 
Published: May 2016

We investigate the convection and dissolution rate generated when a wall of ice dissolves into seawater under Antarctic Ocean conditions. In direct numerical simulations three coupled interface equations are used to solve for interface temperature, salinity and ablation velocity, along with the boundary layer flow and transport. The main focus is on ambient water temperatures between $-1\,^{\circ }\text{C}$ and $6\,^{\circ }\text{C}$ and salinities around 35 ‰, where diffusion of salt to the ice–water interface depresses the freezing point and enhances heat diffusion to the ice. We show that fluxes of both heat and salt to the interface are significant in governing the dissolution of ice, and the ablation velocity agrees well with experiments and a recent theoretical prediction. The same turbulent flow dynamics and ablation rate are expected to apply at any depth in a deeper ocean water column (after choosing the relevant pressure coefficient for the liquidus temperature). At Grashof numbers currently accessible by direct numerical simulation, turbulence is generated both directly from buoyancy flux and from shear production in the buoyancy-driven boundary layer flow, whereas shear production by the convective flow is expected to be more important at geophysical scales. The momentum balance in the boundary layer is dominated by buoyancy forcing and wall stress, with the latter characterised by a large drag coefficient.
POOR FARMERS – POOR YIELDS: SOCIO-ECONOMIC, SOIL FERTILITY AND CROP MANAGEMENT INDICATORS AFFECTING CLIMBING BEAN PRODUCTIVITY IN NORTHERN RWANDA
Authors: FRANKE A. C. , BAIJUKYA F. , KANTENGWA S. , RECKLING M. , VANLAUWE B. , GILLER K.E. 
Published: May 2016

SUMMARYClimbing bean is the key staple legume crop in the highlands of East and Central Africa. We assessed the impact of interactions between soil fertility characteristics, crop management and socio-economic factors, such as household resource endowment and gender of the farmer, on climbing bean productivity and yield responses to basal P fertiliser in northern Rwanda. Through a combination of detailed characterisations of 12 farms and on-farm demonstration trials at 110 sites, we evaluated variability in grain yields and responses to fertiliser. Grain yields varied between 0.14 and 6.9 t ha−1with an overall average of 1.69 t ha−1. Household resource endowment and gender of the farmer was strongly associated with climbing bean yield, even though these were partly confounded with Sector. Poorer households and women farmers achieved lower yields than wealthier households and male farmers. Household resource endowment and gender were likely to act as proxies for a range of agronomic and crop management factors that determine crop productivity, such as soil fertility, current and past access to organic manure and mineral fertiliser, access to sufficient quality staking material, ability to conduct crop management operation on time, but we found evidence for only some of these relationships. Poorer households and female farmers grew beans on soils with poorer soil fertility. Moreover, poorer households had a lower density of stakes, while stake density was strongly correlated with yield. Diammonium phosphate (DAP) fertiliser application led to a substantial increase in the average grain yield (0.66 t ha−1), but a large variability in responses implied that its use would be economically worthwhile for roughly half of the farmers. For the sake of targeting agricultural innovations to those households that are most likely to adopt, the Ubudehe household typology – a Rwandan government system of wealth categorisation – could be a useful and easily available tool to structure rural households within regions of Rwanda that are relatively uniform in agro-ecology.
Using the CSM–CERES–Maize model to assess the gap between actual and potential yields of grain maize
Authors: JING Q. , SHANG J. , HUFFMAN T. , QIAN B. , PATTEY E. , LIU J. , DONG T. , DRURY C. F. , TREMBLAY N. 
Published: May 2016

SUMMARYMaize in Canada is grown mainly in the south-eastern part of the country. No comprehensive studies on Canadian maize yield levels have been done so far to analyse the barriers of obtaining optimal yields associated with cultivar, environmental stress and agronomic management practices. The objective of the current study was to use a modelling approach to analyse the gaps between actual and potential (determined by cultivar, solar radiation and temperature without any other stresses) maize yields in Eastern Canada. The CSM–CERES–Maize model in DSSAT v4·6 was calibrated and evaluated with measured data of seven cultivars under different nitrogen (N) rates across four sites. The model was then used to simulate grain yield levels defined as: yield potential (YP), water-limited (YW, rainfed), and water- and N-limited yields with N rates 80 kg/ha (YW, N-80N) and 160 kg/ha (YW, N-160N). The options were assessed to further increase grain yield by analysing the yield gaps related to water and N deficiencies. The CSM–CERES–Maize model simulated the grain yields in the experiments well with normalized root-mean-squared errors <0·20. The model was able to capture yield variations associated with varying N rates, cultivar, soil type and inter-annual climate variability. The seven calibrated cultivars used in the experiments were divided into three grades according to their simulated YP: low, medium and high. The simulation results for the 30-year period from 1981 to 2010 showed that the average YPwas 15 000 kg/ha for cultivars with high yield potential. The YPis generally about 6000 kg/ha greater than the actual yield (YA) at each experimental site in Eastern Canada. Two-thirds of this gap between YPand YAis probably associated with water stress, as a gap of approximately 4000 kg/ha between the YWand the YPwas simulated. This gap may be reduced through crop management, such as introducing irrigation to improve the distribution of available water during the growing season. The simulated yields indicated a gap of about 3000 and 1000 kg/ha between YWand YW,N-80N for cultivars with high YPand low YP, respectively. The gap between YWand YW,N-160N decreased to <2000 kg/ha for high Ypcultivars with little difference for the low Ypcultivars. The different yield gaps among cultivars suggest that cultivars with high YPrequire high N rates but cultivars with low YPmay need only low N rates.
Analysis of measles-related hospitalizations in Tuscany from 2000 to 2014
Authors: BERTI E. , SOLLAI S. , ORLANDINI E. , GALLI L. , DE MARTINO M. , CHIAPPINI E. 
Published: May 2016

SUMMARYTo evaluate measles incidence and its relevant changes over a 14-year period (2000–2014), we analysed data from the regional hospital discharge database on children and adults hospitalized in Tuscany, Italy. A total of 181 paediatric and 413 adult cases were identified. Despite all the efforts towards regional measles elimination, we observed that the overall measles hospitalization rates for children and adults living in Tuscany globally increased from 0·45 to 0·85/100 000 during the study period (P = 0·001) showing fluctuations due to periodic measles outbreaks. Data stratified by age group showed that the hospitalization rate significantly increased in young adults over the study period, confirming an increase in susceptibility to measles in this subpopulation. Conversely, no statistically significant difference was observed in the hospitalization rate in the other age groups. However, children aged <1 year still exhibit the highest hospitalization rate. Pneumonia represented the most common complication in both the adult and children subsets. No death was reported. Measles still represents a public health problem, and national strategies should be implemented, focusing on emergent susceptible subsets, such as infants and young adults.
Status of the Northern Silvery Grebe Podiceps juninensis in the northern Andes: recent changes in distribution, population trends and conservation needs
Authors: GUEVARA ESTEBAN A. , SANTANDER G. TATIANA , SORIA ADRIÁN , HENRY PIERRE-YVES 
Published: May 2016

SummaryThe Northern Silvery Grebe Podiceps juninensis is an aquatic bird species considered Vulnerable to extinction in Ecuador and Endangered in Colombia. Globally the species is considered Near Threatened. Herein we report recent changes in distribution and population trends for the subpopulation in the northern Andes (Ecuador, Colombia), which is small and isolated. The Northern Silvery Grebe has undergone two documented extirpations, and at least one colonisation event, over the last three decades. More than 90% of the subpopulation relies on two wetlands, La Mica and Colta lakes in Ecuador, with the latter facing an accelerated sedimentation process which jeopardizes the fate of the wetland, and the species, in the mid-term. The population of La Mica lost 80% of its birds in 2000 after the damming of the lake, but then remained stable over our census period (2004–2013). In contrast, the Colta population results from a recent colonisation in the early 2000s, and has experienced an exponential growth since then (annual population multiplication rate: 1.464). The growth of this population is so fast that it must include an important contribution of immigrants. The temporal coincidence between the drop in population size at lake La Mica and the colonisation of lake Colta suggests that the Colta population was founded by immigrants from La Mica. Finally, the absence of current reports of the species at wetlands in Colombia suggests that the species remains at very low numbers, bolstering the shrinkage in northern distribution.
Modulation of Executive Control in the Task Switching Paradigm With	Transcranial Direct Current Stimulation (tDCS)
Authors: Strobach Tilo , Antonenko Daria , Schindler Tamara , Flöel Agnes , Schubert Torsten 
Published: May 2016

Abstract. Executive processing in the task switching paradigm is primarily associated with activation of the lateral prefrontal cortex (lPFC), demonstrated in numerous functional imaging studies (e.g., Brass & von Cramon, 2002 ). However, there are only very few attempts to modulate neural activation related with executive functions and to investigate the effects of this modulation on the performance in this paradigm. To modulate lPFC activity here, we used the non-invasive transcranial Direct Current Stimulation (tDCS; atDCS [1 mA, 20 min] vs. ctDCS [1 mA, 20 min] vs. sham stimulation [1 mA, 30 s]) over the left inferior frontal junction under conditions of single tasks, task repetitions, and task switches in the task switching paradigm. We assessed the performance effects of online tDCS on mixing costs (single tasks vs. task repetitions) as well as on switching costs (task repetitions vs. task switches). In a within-subjects design across three sessions, there was no evidence of stimulation on the magnitude of these cost types. However, when taking a between-subjects perspective in the first session (i.e., after excluding dominant effects of task experience), atDCS showed an increase in mixing costs in contrast to ctDCS and sham. We interpreted this finding in the context of task switching theories on task activation and task inhibition and their neural localizations.