bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nasal Polyp Cell Populations and Fungal-Specific Peripheral Blood Lymphocyte Proliferation in Allergic Fungal Sinusitis
Authors: Pant Harshita , Beroukas Dimitra , Kette Frank E. , Smith William B. , Wormald Peter J. , Macardle Peter J. 
Published: October 2024

Background Allergic fungal sinusitis (AFS) is considered a different disease from other polypoid chronic rhinosinusitis diseases (CRS) with eosinophilic mucus (EM) termed eosinophilic mucus chronic rhinosinusitis (EMCRS). To substantiate this, studies on cellular responses to fungi and sinus mucosal inflammatory cell populations in AFS and other EMCRS diseases are. required. This study was designed to examine polyp inflammatory cell populations and peripheral blood fungal-specific T-cell responses in AFS, other EMCRS subgroups (defined later), and polypoid CRS without EM. Methods A prospective study was performed. Clinical characteristics, including CRS symptoms, sinus computed tomography (CT) scans, allergy status, intraoperative endoscopy, presence of EM, and fungal culture results were used to define patient groups. Polyps and peripheral blood were examined for populations of eosinophils, lymphocytes (CD4+, CD8+ T cells, natural killer cells, and B cells), and neutrophils using immunohistochemistry, cytospin preparations and flow cytometry. Fungal-specific peripheral blood lymphocyte proliferation was examined in AFS patients, other EMCRS patients, CRS patients, and controls. Results There was no significant difference in the percentage of cell populations and fungal-specific lymphocyte proliferation between AFS and other EMCRS diseases. However, AFS and other EMCRS polyps had a higher percentage of eosinophils and CD8+ T cells whereas CRS polyps had higher CD44 T cells. Fungal-specific lymphocyte proliferation was significantly greater in AFS and other EMCRS patients regardless of fungal allergy, whereas in CRS and controls, higher proliferation was observed in fungal-allergic individuals. Conclusion These findings question the basis for differentiating AFS from, other EMCRS diseases based on fungal allergy and fungi in EM. Fungal-specific cellular response was present in AFS and other EMCRS diseases, different from, that associated with fungal allergy, suggesting a nonallergic fungal immune response. Increased CD8+ T cells in EMCRS polyps signify a different type of inflammation to CRS that may be driven by CD8+ T cells.
Novel cytotoxicity of nano-coated orthodontic micro-implants: An in vitro study
Authors: Othman Samer Salim , Albagdaly Mohammed Q. , Nahidh Mohammed , Hameed Mohammed Abdullah , Marrapodi Maria Maddalena , Cicciù Marco , Minervini Giuseppe 
Published: October 2024

Objectives:
Many attempts have been made to modify the surface of orthodontic micro-implants and prevent the development of microbes by coating them with antimicrobial nanoparticles (NPs). The purpose of the present study was to evaluate the cytotoxicity of different NPs, namely, TiO2 and zinc oxide (ZnO) NPs, that are used to coat titanium orthodontic micro-implants.

Material and Methods:
Thirty orthodontic micro-implants were included in this study. Those were divided into three groups: control group without coating, TiO2-coated orthodontic micro-implants, and TiO2- and ZnO-coated orthodontic micro-implants. Scanning electron microscope, energy-dispersive spectroscopy (EDS), and cytotoxicity tests were applied for all groups.

Results:
The results of scanning electron microscopy and EDS showed effective deposition of the titanium oxide layer onto the micro-implants. The ZnO layer applied on the micro-implants exhibited superior physicochemical characteristics in comparison to the uncoated samples with no significant cytotoxicity.

Conclusion:
Both NPs showed biocompatibility with the oral tissues.
Comparative study of microneedling monotherapy versus microneedling with autologous platelet-rich plasma for the treatment of stretch marks (striae distensae) and post-surgical scars: Clinical and dermoscopy outcomes
Authors: Kaur Tejinder , Kaur Sahibpreet , Bagga Permeet Kaur , Sidhu Sandeep , Raj Rakesh Tilak 
Published: October 2024

Objectives:
Stretch marks and post-surgical scar marks may have negative cosmetic and psychological impacts.. Thus, this study aimed to compare the efficacy and safety of microneedling monotherapy versus microneedling in combination with autologous platelet-rich plasma (PRP) for the treatment of stretch marks and post-surgical scars.

Material and Methods:
This was a prospective randomized non-controlled study. A total of 30 study participants with stretch marks and post-surgery scars were enrolled and randomly divided into two groups, each with 15 study participants. All received three treatment sessions using microneedling monotherapy (Group A) or autologous PRP with microneedling (Group B) at 4-week intervals. Clinical response to treatment was assessed at the end of 20 weeks by comparing clinical photographs, Manchester Scar scale (MSS) score, dermoscopy images, and patient satisfaction scores.

Results:
At the end of the study, statistically significant esthetic improvement in terms of MSS scores was seen in Group B when compared to Group A. In Group A, 73.3% of the study participants were satisfied while in Group B, 86.6% were very satisfied with the results. Dermoscopy pictures substantiated the findings of clinical improvement. No major side effects were documented.

Conclusion:
PRP in combination with microneedling has a better outcome as compared to microneedling monotherapy. Furthermore, dermoscopy is a non-invasive tool that can be used to evaluate therapeutic response.
Dietary and Social Stratification: An Anthropological Perspective
Authors: Cai Runjia 
Published: October 2024

The number of articles dedicated to dietary and social stratification today is relatively small, and those that exist are often based on quantitative statistics rather than direct observations and narratives of people. This article aims to describe and analyze these phenomena, revealing the often invisible and nuanced social stratifications and definitions. This article uses phenomenological interpretation and analysis, providing an arrative overview of people’s choices and needs regarding their diets. Although diet continues to be influenced by social stratification, this influence is gradually diminishing, eliminating the monopoly of the upper stratum. While this article is primarily a phenomenological exposition, it argues that the relationship between dietary and social stratification is not unidirectional and proportional but rather influenced through multiple connections.
Nilai-Nilai Budaya Jawa dalam Cerita Panji Semirang
Authors: Pradana Susilo Andri Pradana , Budiyono Sunu Catur 
Published: October 2024

Penelitian ini bertujuan untuk mendeskripsikan nilai-nilai budaya Jawa dalam cerita Panji Semirang menggunakan teori sosiologi sastra menurut Damono (1984: 6). Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan metode deskriptif. Data dan sumber data yang digunakan berupa wawancara budayawan panji Henri Nurcahyo, Bungurasih Sidoarjo pada 24 Desember 2023 berdurasi 53 menit 32 detik dan Seri Naskah Kuna Nusantara No. 38 Perpustakaan Republik Indonesia berjudul Hikayat Panji Kuda Semirang Alih Aksara ditulis oleh Ahmad Budi Wahyono pada tahun 2018 berjumlah 122 halaman. Teknik pengumpulan data yang digunakan dalam penelitian ini, yaitu metode triangulasi. Teknik triangulasi merupakan teknik untuk mendapatkan kreadibilitas data, peneliti selaku instrumen kunci melakukan pengecekan data dari berbagai sumber tentang cerita Panji Semirang dengan teknik yang berbeda, yaitu wawancara dan dokumen. Berdasarkan hasil analisis, ditemukan nilai-nilai budaya Jawa dalam cerita Panji Semirang yang terdiri atas 4 nilai keagamaan yang meliputi keimanan tauhidan manusia terhadap Tuhan, keteringatan manusia terhadap Tuhan, ketaatan manusia terhadap firman Tuhan, kepasrahan manusia terhadap kekuasaan Tuhan, dan 5 nilai etika berupa kesahajaan, menerima kenyataan, keseimbangan mental, sembada, nalar, serta terdapat 2 nilai sosial, yaitu bakti dan rukun.
Mathematics Learners’ Performance and Academic Achievement at a Public High School Institution in Leyte, Philippines
Authors: Cabuquin Jomar Cobacha , Abocejo Ferdinand Tesado 
Published: October 2024

<table border="1" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="369"><p>This study examined the correlation between mathematics performance and academic achievement of junior high school learners in a government-run laboratory high school institution and compared the mathematics performance and academic achievement of male and female learners. Correlational and comparative research designs were employed to analyze the gathered secondary data. Findings revealed a positive and highly significant correlation between the learners' mathematics performance and academic achievement, indicating that high school learners who are adept in mathematics tend to succeed and perform better in their academic courses. Whereas low performance in mathematics correspondingly connotes low achievement in overall academic abilities. No significant difference was found between male and female learners, suggesting that both genders of learners can succeed academically. The study concludes that mathematics performance and academic achievement go hand in hand, while gender does not affect the learners' ability to excel in mathematics. Effectively, secondary learning institutions must provide mathematics learners with learning opportunities during Mathematics classes and classroom activities regardless of gender. Teachers must help learners understand how to solve problems and think critically, expose them to real-world applications, and build their confidence and motivation to excel academically.</p><p> </p></td></tr></tbody></table>
Evaluating the safety and efficacy of medical management in extracranial pseudoaneurysms: a comparative study
Authors: Filo Jean , Ramirez-Velandia Felipe , Lawlor Donna , Young Michael , Pettersson Samuel D. , Fodor Thomas B. , Enriquez-Marulanda Alejandro , Muram Sandeep , McDonald John , Shutran Max , Granstein Justin H. , Taussky Philipp , Ecker Robert D. , Ogilvy Christopher S. 
Published: October 2024

OBJECTIVE
As endovascular interventions become safer and their use more prevalent for treating extracranial pseudoaneurysms, fewer pseudoaneurysms are treated with medical therapy alone. This study aimed to assess the indications for intervention and the safety of medical management.

METHODS
A dual-center retrospective analysis was conducted on patients diagnosed with extracranial carotid and vertebral pseudoaneurysms between December 2006 and June 2023.

RESULTS
Of 145 pseudoaneurysms, 121 (83%) received medical therapy, 22 (15%) were treated endovascularly, and 2 (1.4%) were treated with open surgery. In the medical group, there were 2 (1.9%) complications, one unrelated to the pseudoaneurysm. In the intervention group, there were 3 (16%) complications, with 1 patient requiring two retreatments and sacrifice of the vessel. Major trauma (OR 4.0, 95% CI 1.3–14; p = 0.02), use of digital subtraction angiography as the initial imaging modality (OR 9.8, 95% CI 2.5–42; p < 0.01), and a maximum lesion diameter > 6 mm (OR 5.3, 95% CI 1.4–25; p = 0.03) proved to be significant in the decision to intervene. At a median follow-up of 18.1 months, 94.7% of the lesions treated with intervention healed completely compared with 19% of aneurysms in the medical group. Among those medically managed that did not resolve, the median change in diameter was −0.4 mm (IQR −1.8 to 0.4 mm). Age ≤ 50 years and aneurysm maximum diameter ≤ 6 mm predicted healing at follow-up in the medical group with 92% specificity and 65% sensitivity (area under the curve 0.87). At follow-up, 98% of patients were functionally independent (modified Rankin Scale score ≤ 2).

CONCLUSIONS
Medical management alone is safe for most extracranial pseudoaneurysms, resulting in significantly fewer complications than endovascular intervention. Maximum diameter ≤ 6 mm and age ≤ 50 years were significant predictors of pseudoaneurysm resolution with medical therapy alone. Lesions that do not heal do not cause further symptoms or require additional intervention.
Semaglutide exposure and its association with adverse outcomes in diabetic patients undergoing transforaminal lumbar interbody fusion for lumbar degenerative disc disease
Authors: Khalid Syed I. , Massaad Elie , Thomson Kyle , Shin John H. 
Published: October 2024

OBJECTIVE
Semaglutide, a novel glucagon-like peptide–1 receptor agonist, has transformed the therapeutic landscape for type 2 diabetes mellitus. However, its effect on osteoclast activity and its potential to induce weight-related muscle loss raises concerns about its impact on spine surgery outcomes. As such, evaluating semaglutide’s influence on transforaminal lumbar interbody fusion (TLIF) is imperative, given the procedure’s reliance on successful bony fusion to prevent postoperative instability and further interventions.

METHODS
Using an all-payer database (MARINER), the authors analyzed data from patients with type 2 diabetes mellitus who were 18–74 years of age and who underwent short-segment fusion (≤ 3-level) TLIFs between January 2018 and October 2022. Patients were either exposed to semaglutide or not. A comprehensive 1:3 (exposure vs no exposure) matching was performed based on age, sex, obesity, hypertension, coronary artery disease, chronic kidney disease, smoking status, osteoporosis, levels of surgery, and basal-bolus insulin dependence. Kaplan-Meier survival curves and log-rank testing were performed to study the probability of additional lumbar fusion surgery within 1 year.

RESULTS
After the 1:3 matching, 1781 patients were identified, with 447 in the semaglutide-exposed cohort and 1334 in the nonexposed cohort. Most patients in both groups were 55–69 years old, and 59.3% were female. Analysis showed that the likelihood of undergoing additional lumbar fusion surgery within 1 year post-TLIF was significantly higher in the semaglutide-exposed group than in the nonexposed group (OR 11.79, 95% CI 8.17–17.33). Kaplan-Meier plots and log-rank testing further confirmed a statistically significant divergent probability in the need for additional surgery within 1 year between the cohorts (log-rank, p < 0.001).

CONCLUSIONS
Semaglutide exposure appears to be associated with a higher likelihood of additional lumbar fusion surgeries within 1 year post-TLIF, especially in patients receiving the medication for longer durations. Although the mechanisms remain speculative, potential impacts on bone turnover and the onset of muscle loss may be contributory factors. Further research is needed to elucidate the exact mechanisms and to develop strategies for optimizing surgical outcomes in these patients.
Association between social determinants of health and select neurosurgical procedures in the National Spina Bifida Patient Registry
Authors: Punchak Maria A. , Miranda Stephen , Montgomery Canada , Agbodza Ena , Chauhan Daksh , Houtrow Amy , Smith Kathryn , Foy Andrew B. , Leonard Jeffrey R. , Castillo Heidi , Castillo Jonathan , Cady Rhonda G. , Bowman Robin M. , Freeman Kurt A. , Rocque Brandon G. , Flanders Tracy M. , Heuer Gregory G. 
Published: October 2024

OBJECTIVE
Myelomeningocele (MMC) is a lifelong condition requiring complex multidisciplinary management. Using the National Spina Bifida Patient Registry (NSBPR), the authors tested the association between sociodemographic variables and odds of undergoing neurosurgical procedures.

METHODS
The authors extracted sociodemographic, clinical, and neurosurgical procedure data on participants with MMC aged ≥ 1 year who visited an NSBPR clinic between 2009 and 2020. The zip code of the participant’s residence at the time of the last spina bifida clinic visit was linked to the Distressed Communities Index (DCI) tier. Multivariate models were built to identify factors associated with undergoing CSF diversion, shunt revision, tethered cord release (TCR), and Chiari decompression.

RESULTS
There were 7924 participants with a median visit age of 13 years (IQR 7–20 years); 49.1% were male, 30.2% were non-Hispanic Black or Hispanic, 54.5% had public/supplemental insurance, and 16.9% were from distressed communities. CSF diversion, shunt revision, TCR, and Chiari decompression were performed in 81.8%, 47.7%, 22.9%, and 8.7% of participants, respectively. In multivariate analyses controlling for age, sex, insurance, DCI tier, lesion level, and surgical closure timing, Hispanic individuals were less likely than their non-Hispanic White counterparts to undergo shunt revision (p = 0.013). Non-Hispanic Black and Hispanic individuals were less likely to undergo TCR (p < 0.001 each) or Chiari decompression (p < 0.001 each). Compared with privately insured individuals, publicly insured individuals were more likely to undergo CSF diversion (p = 0.031). Those in distressed communities had increased odds of undergoing CSF diversion (p = 0.004) than those in prosperous communities.

CONCLUSIONS
Among individuals with MMC participating in the NSBPR, there were differences in receiving neurosurgical procedures by race/ethnicity, insurance type, and DCI tier. Additional prospective studies are necessary to elucidate the reasons for these variations and their impact on long-term outcomes for this patient population in order to created targeted interventions.
Stereotactic radiosurgery for arteriovenous malformations in pediatric patients: an updated systematic review and meta-analysis
Authors: Tos Salem M. , Mantziaris Georgios , Shaaban Ahmed , Dayawansa Neil , Motawei Ahmed Sallam , Sheehan Jason P. 
Published: October 2024

OBJECTIVE
Intracranial arteriovenous malformations are the most common cause of intracranial hemorrhages in pediatric patients. Stereotactic radiosurgery (SRS) has been used extensively to treat these lesions. The authors conducted a systematic review and meta-analysis to report treatment outcomes and long-term complications.

METHODS
This study follows the PRISMA and MOOSE guidelines, with the search spanning electronic databases up to February 6, 2024. The outcome measures included obliteration rate, hemorrhage in the latency period, symptomatic radiation-induced changes (RICs), cyst formation, and radiation-induced tumorigenesis.

RESULTS
A total of 1493 patients across 24 studies were included. The pooled complete obliteration after single-fraction SRS was 64.7% (95% CI 58%–69%). The pooled post-SRS hemorrhage rate at the final follow-up was 6.2% (95% CI 5%–8%). The overall incidence rate of RIC was 31.3% (267/854 patients), and the incidence of symptomatic RIC was 8.8% (114/1289 patients). For permanent symptomatic RIC, the pooled incidence was 4.8% (62/1283 patients). At final follow-up, 17 cases of radiation-induced necrosis were documented among 654 patients (2.6%). Similarly, cyst formation was reported in 1.3% of cases (17/1265 patients) and radiation-induced tumors occurred in 0.15% of cases (2/1342 patients).

CONCLUSIONS
SRS can be considered an effective intervention for appropriately selected pediatric patients with arteriovenous malformations. Long-term complication rates appear to be low but additional longitudinal studies are required to better define the long-term outcomes.
Three-dimensional imaging in craniofacial surgery: utilization of a novel 3D mobile application to evaluate the surgical outcomes of a skull recontouring procedure for cephalohematoma
Authors: Jung Geena , Buckner-Wolfson Emery , Reisert Hailey , Keymakh Margaret , Kim Timothy , Fatemi Ryan , Pasuizaca Andres , Shah Pushti , Cohen Joshua , Naseri Alavi Seyed Ahmad , Liriano Genesis , Kobets Andrew 
Published: October 2024

OBJECTIVE
Cranial abnormalities are common birth defects that frequently alter skull shape and appearance. Despite their prevalence, objective quantification of defect severity pre- and posttreatment is limited. The authors evaluated the ability of MirrorMe3D, a novel 3D mobile iPhone application, to measure changes in the contour of the skull for patients undergoing contouring of a calcified cephalohematoma.

METHODS
The heads of two 20-month-old patients with disfiguring right parietal cephalohematomas undergoing a skull recontouring operation were scanned pre- and postsurgery. Four scans of the cranial abnormality were taken throughout the procedure and intraoperative 3D models were generated. Models of the head were overlapped pre- and postsurgery and compared using a depth analyzer built into MirrorMe3D.

RESULTS
Depth analysis revealed 6.0-mm and 9.9-mm differences for patients 1 and 2, respectively. Volume analysis revealed 33-cm3 and 85-cm3 differences for patients 1 and 2, respectively. Currently, no standard for quantitative measurement of the surgical outcomes of a skull reconstruction procedure exists.

CONCLUSIONS
MirrorMe3D provides an efficient method for monitoring patients with simple topographic scans that create accurate models of the head. The authors show the app’s ability to capture the severity of a calcified cephalohematoma and quantify the changes in the contour of the skull before and after surgery.
Batubara Police Organizational Communication In The Implementation Of Predictive, Responsibility And Transparent (Precise) Police: Islamic Communication Perspective
Authors: Gultom Rohim Martin , Lahmuddin Lahmuddin , Ritonga Elfi Yanti 
Published: October 2024

<table border="0" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="186"><p class="TableParagraph"><strong><em>Article Info</em></strong></p></td><td valign="top" width="388"><p class="TableParagraph"><strong><em><span style="text-decoration: underline;"> Abstract </span></em></strong><strong><em></em></strong></p></td></tr><tr><td valign="top" width="186"><p class="TableParagraph"><em>Received: </em></p><p class="TableParagraph"><em>Revised: </em></p><p class="TableParagraph"><em>Accepted:</em></p><p class="TableParagraph"> </p><p class="TableParagraph"><strong><em>Keywords:</em></strong></p><p class="TableParagraph"><em>Organizational Communication, Batubara Police, Predictive Police, Responsibility and Transparency (Precision), Islamic Communication.</em></p><p class="TableParagraph"><em>Introduction.</em></p></td><td valign="top" width="388"><p class="TableParagraph"><em>This research aims to analyze and interpret the communication of the Batubara Police organization in implementing predictive, responsibility and transparency (Presisi) police policies in Batubara Regency, using an Islamic communication perspective approach. This research adopts a descriptive qualitative method to observe the natural phenomenon of Batubara Police organizational communication. Research data was obtained through interviews with the Police Chief, Deputy Police Chief, Police Propam, Police Sumda Section, Police Binmas Unit, and Batubara Police Traffic Unit, as well as through documents relevant to the research focus, such as pictures, photos, notes or related writings. . Data collection was carried out through interviews, observation and documentation studies. Data analysis was carried out using reduction, presentation and conclusion techniques. The validity of the data was tested using triangulation techniques. The research results confirm that effective organizational communication, rooted in Islamic principles, and supported by the application of precision at the Batubara Police has a key role in fostering positive relations with the community. By presenting information openly and clearly and providing responsive and responsible services, the police can build a positive image and increase public trust. The synergy between effective communication, Islamic values, and precise application is a vital foundation for achieving the goal of quality public services and increasing the level of public trust. However, handling inhibiting factors, such as unprofessional behavior, is required through strict internal supervision and ongoing training to increase the competence of police officers.</em></p></td></tr></tbody></table>