bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward Electronic Health Recording: Evaluation of Electronic Patient-reported Outcome Measures System for Remote Monitoring of Early Rheumatoid Arthritis
Authors: El Miedany Yasser , El Gaafary Maha , Youssef Sally , Bahlas Sami , Almedany Samah , Ahmed Ihab , Palmer Deborah 
Published: September 2016

Objective.To assess the use of electronic patient-reported outcome measures (ePROM) in standard clinical practice for early rheumatoid arthritis (RA) management, the ePROM ability to enhance clinical care, and how computing technology can improve the patients’ adherence to therapy.Methods.In a double-blinded randomized-controlled study, 211 patients with early RA diagnosed according to American College of Rheumatology/European League Against Rheumatism criteria completed a PROM in paper format at their first clinic visit. Patients were then randomized to Group 1, which completed an ePROM questionnaire monthly, or Group 2, which continued the standard paper PROM format. Over a 12-month period, Group 1 patients were assessed every 3 months in the clinic, whereas Group 2 patients were assessed in the clinic initially monthly for 6 months, then every 3 months. The primary endpoint was the equivalence of outcomes [Routine Assessment of Patient Index Data 3 (RAPID-3) and 28-joint Disease Activity Score (DAS28)] in both groups. The secondary endpoint was the patients’ adherence to their medications.Results.There was no significant difference between disease activity measures as well as DAS28 and RAPID-3 scores at 3, 6, and 12 months of management, although there was a trend toward lower patient-reported tender joint count and functional disability score in the active group versus the control group. The patients’ adherence to antirheumatic therapy was significantly higher (p < 0.01) in the ePROM group, whereas stopping disease-modifying antirheumatic drugs for intolerability was significantly higher (p < 0.01) in the control group at 12 months of treatment.Conclusion.We found ePROM equivalent to standard paper PROM format. Further, it enabled the patients to personally monitor how they are doing regarding their disease activity and helped to optimize their adherence to their treatment.
Intraocular Pressure in Premature Low Birth Weight Infants
Authors: Grover Sandeep , Zhou Zimei , Haji Shamim , Khaja Wassia , Sambhav Kumar , Stass-Isern Merrill , Chalam K.V. 
Published: September 2016

Purpose:
To evaluate the intraocular pressure (IOP) and central corneal thickness (CCT) in premature low birth weight (LBW) infants and their correlation with gestational age (GA).

Methods:
IOP and CCT were measured in premature LBW infants (defined as a birth weight ≤ 1,500 g or birth GA ≤ 30 weeks) admitted to the neonatal intensive care unit at the University of Florida Division of Neonatology, UF Health Jacksonville.

Results:

Ninety eyes of 45 premature LBW infants with mean birth GA of 28.2 ± 2.3 weeks and mean birth weight of 1,131.5 ± 380.1 g were evaluated. The mean IOP and CCT were 29.0 ± 9.0 mm Hg and 660.0 ± 65.0 µm, respectively. There was no correlation between the IOP and CCT (
r
= 0.09;
P
= .38). There was a negative correlation between IOP and GA (
r
= −0.41) and between CCT and GA (
r
= −0.26).

Conclusions:
IOP is higher and CCT is thicker in premature infants compared to adults; however, there was no correlation between IOP and CCT.

[
J Pediatr Ophthalmol Strabismus
. 2016;53(5):300–304.]
Vol retour sur la consultation relative au projet d’aéroport de Notre-Dame-des-Landes
Authors: Duval Eugénie 
Published: September 2016

Le 26 juin dernier, les électeurs de la Loire-Atlantique se sont prononcés en faveur du projet de transfert de l’aéroport de Nantes-Atlantique sur la commune de Notre-Dame-des-Landes. Ce projet d’aéroport faisant l’objet d’une contestation importante et ancienne, la consultation visait à dépasser cette situation de « blocage ». Or, la désinvolture dont a fait preuve l’Exécutif dans son organisation n’est pas à la hauteur de l’enjeu : la démocratie, tant représentative que « participative », en sort affaiblie.
Role of Metabolism in the Immunobiology of Regulatory T Cells
Authors: Galgani Mario , De Rosa Veronica , La Cava Antonio , Matarese Giuseppe 
Published: September 2016

Abstract
Intracellular metabolism is central to cell activity and function. CD4+CD25+ regulatory T cells (Tregs) that express the transcription factor FOXP3 play a pivotal role in the maintenance of immune tolerance to self. Recent studies showed that the metabolism and function of Tregs are influenced significantly by local environmental conditions and the availability of certain metabolites. It also was reported that defined metabolic programs associate with Treg differentiation, expression of FOXP3, and phenotype stabilization. This article reviews how metabolism modulates FOXP3 expression and Treg function, what environmental factors are involved, and how metabolic manipulation could alter Treg frequency and function in physiopathologic conditions.
Machos violentos y peligrosos. La figura del maltratador en el cine almodovariano
Authors: Caballero Gálvez Antonio A. , Zurian Hernández Francisco A. 
Published: September 2016

La violencia contra las mujeres por parte de los hombres es una forma de reafirmar la masculinidad e imponer su hegemonía a través de la fuerza. Planteamos el estudio de la violencia de género en el cine almodovariano, no a partir de la víctima, sus personajes femeninos, sino a través de la figura del maltratador. Metodología. Realizamos dos modelos analíticos complementarios, como son: 1) la semiótica visual desde la perspectiva de los estudios de género, 2) la cuantificación de la tipología de maltratos llevados a cabo por los personajes masculinos representados en el cine de Almodóvar, así como los factores que definen a estos arquetipos. Resultados y Conclusiones. Dentro de la amalgama de masculinidades representadas en el cine de Almodóvar existen diferentes tipos de personajes masculinos que agreden a la mujer a través del acoso, la violación y el asesinato.
First-year medical undergraduate students opinion about the use of radiology in gross anatomy course
Authors: Silva V. , Vilela D. , Gonçalves F. , Regacini R. 
Published: September 2016

Abstract
Introduction: Although the importance of anatomy teaching in the undergraduate medical curriculum is incontestable, the lack of knowledge retention and clinical application are the greatest challenges for anatomy teachers. New teaching methodologies are replacing cadaver' dissection in many schools around the world and the usage of radiologic images can become a valuable resource for student's learning the human body structures. The aim of this article was to analyze the perception of first-year undergraduate medical students in the usage of radiology in gross human anatomy course. Materials and methods: One hundred students answered a 30 questions survey using a 5-point Likert scale about the usage of radiologic images in the human anatomy classes. Results: Most subjects have shown desire and the availability to learn human anatomy using images. After the usage of radiologic images there has been an increase on the subjective aspects of the human body such as admiration and respect, an improvement in the correlation of human anatomy with clinical aspects and in the three dimensional perception of the human body anatomic structures. Conclusions: Most of the research participants evaluated the usage of radiologic images as positive and beneicial for the teaching and learning human anatomy as it increases the interest for anatomy and it can favor learning and clinical practice performance. Results shows that according to students' opinion the usage of radiology can be an excellent complement in human anatomy learning and can induce us to think it can prepare and train more competent doctors in diagnostic imaging.
A study of the clinico-anatomical variations in the shape and size of gallbladder
Authors: Nadeem G. 
Published: September 2016

Abstract
Introduction: The structure and size of gallbladder, it's normal and a variation are forming an interesting field of study, and has gained importance Anatomically and Surgically. The gallbladder surgeries have drawn the attraction of surgeons because of lot of interesting and numerous variations present in them. Materials and Methods: The study was carried on 100 gallbladder from cadavers of all age groups. Results: In our study, the length of the gallbladder ranged from 4.5-11.6 cm, breadth from 2.7-5.2 cm. The shapes of the gallbladder varied from pear (82.85%), Hartman's pouch (7.14%), cylindrical (2.86%), flask shaped (2.86%), hour glass (1.43%), bilobed (1.43%) and irregular (1.43%). Some gallbladders with mesentery (1.30%) and horizontally placed (4.30%) gallbladders were also found. Conclusion: The indings showed various anatomical variations pertaining to shape and position, which are to be taken into account for radiological study, Investigative procedures, surgical interventions, clinical implications and comparative anatomy.
Localization of sterodogenic acute regulartory (StAR) protein in testis of Thai red jungle fowl (Gallus gallus gallus)
Authors: Iamsaard S. , Chaichun A. , Sukhorum W. 
Published: September 2016

Abstract
Introduction: Thai red jungle fowl (Gallus gallus gallus) has been focusing on genetic profiles besides phenotypical features. The husbandry of this species is still limited. Basic understanding of its reproductive systems may be useful for breeding applications. Additionally, the morphology of testes and epididymis of Thai red jungle fowl has never been elucidated. Material and Methods: This study has examined the gross structure and histology of those organs of male Thai Gallus gallus gallus at 24th weeks (age and sexual maturity). Moreover, the localization of sterodogenic acute regulartory (StAR) protein in the testis was also performed by immunohistochemistry. Results: The results showed that the mature testes were oval shape with 1.56 ± 0.584 cm. in length and 1.20 ± 0.067 cm. in width, respectively. General histology of testes and epididymis was similar to those of maturely domestical birds. Expectedly, the StAR protein was first localized in the leydig cells of Thai red jungle fowl. Conclusion: These findings are fundamental data that may be applied to the breeding process.
Saharan dust contribution to the Caribbean summertime boundary layer –
a lidar study during SALTRACE
Authors: Groß Silke , Gasteiger Josef , Freudenthaler Volker , Müller Thomas , Sauer Daniel , Toledano Carlos , Ansmann Albert 
Published: September 2016

Abstract. Dual-wavelength lidar measurements with the small lidar system POLIS of the Ludwig-Maximilians-Universität München were performed during the SALTRACE experiment at Barbados in June and July 2013. Based on high-accuracy measurements of the linear depolarization ratio down to about 200 m above ground level, the dust volume fraction and the dust mass concentration within the convective marine boundary layer can be derived. Additional information from radiosonde launches at the ground-based measurement site provide independent information on the convective marine boundary layer height and the meteorological situation within the convective marine boundary layer. We investigate the lidar-derived optical properties, the lidar ratio and the particle linear depolarization ratio at 355 and 532 nm and find mean values of 0.04 (SD 0.03) and 0.05 (SD 0.04) at 355 and 532 nm, respectively, for the particle linear depolarization ratio, and (26 ± 5) sr for the lidar ratio at 355 and 532 nm. For the concentration of dust in the convective marine boundary layer we find that most values were between 20 and 50 µgm−3. On most days the dust contribution to total aerosol volume was about 30–40 %. Comparing the dust contribution to the column-integrated sun-photometer measurements we see a correlation between high dust contribution, high total aerosol optical depth and a low Angström exponent, and of low dust contribution with low total aerosol optical depth.
Investigation of a potential HCHO measurement artifact from ISOPOOH
Authors: St. Clair Jason M. , Rivera-Rios Jean C. , Crounse John D. , Praske Eric , Kim Michelle J. , Wolfe Glenn M. , Keutsch Frank N. , Wennberg Paul O. , Hanisco Thomas F. 
Published: September 2016

Abstract. Recent laboratory experiments have shown that a first generation isoprene oxidation product, ISOPOOH, can decompose to methyl vinyl ketone (MVK) and methacrolein (MACR) on instrument surfaces, leading to overestimates of MVK and MACR concentrations. Formaldehyde (HCHO) was suggested as a decomposition co-product, raising concern that in situ HCHO measurements may also be affected by an ISOPOOH interference. The HCHO measurement artifact from ISOPOOH for the NASA In Situ Airborne Formaldehyde instrument (ISAF) was investigated for the two major ISOPOOH isomers, (1,2)-ISOPOOH and (4,3)-ISOPOOH, under dry and humid conditions. The dry conversion of ISOPOOH to HCHO was 3 ± 2 % and 6 ± 4 % for (1,2)-ISOPOOH and (4,3)-ISOPOOH, respectively. Under humid (relative humidity of 40–60 %) conditions, conversion to HCHO was 6 ± 4 % for (1,2)-ISOPOOH and 10 ± 5 % for (4,3)-ISOPOOH. The measurement artifact caused by conversion of ISOPOOH to HCHO in the ISAF instrument was estimated for data obtained on the 6 September 2013 flight of the Studies of Emissions and Atmospheric Composition, Clouds and Climate Coupling by Regional Surveys (SEAC4RS) campaign. Prompt ISOPOOH conversion to HCHO was the source of < 4 % of the observed HCHO, including in the high-isoprene boundary layer. Time-delayed conversion, where previous exposure to ISOPOOH affects measured HCHO later in the flight, was conservatively estimated to be < 10 % of observed HCHO, and is significant only when high ISOPOOH sampling periods immediately precede periods of low HCHO.
Comparison of the aerosol optical properties and size distribution retrieved
by sun photometer with in situ measurements at midlatitude
Authors: Chauvigné Aurélien , Sellegri Karine , Hervo Maxime , Montoux Nadège , Freville Patrick , Goloub Philippe 
Published: September 2016

Abstract. Aerosols influence the Earth radiative budget through scattering and absorption of solar radiation. Several methods are used to investigate aerosol properties and thus quantify their direct and indirect impacts on climate. At the Puy de Dôme station, continuous high-altitude near-surface in situ measurements and low-altitude ground-based remote sensing atmospheric column measurements give the opportunity to compare the aerosol extinction measured with both methods over a 1-year period. To our knowledge, it is the first time that such a comparison is realised with continuous measurements of a high-altitude site during a long-term period. This comparison addresses to which extent near-surface in situ measurements are representative of the whole atmospheric column, the aerosol mixing layer (ML) or the free troposphere (FT). In particular, the impact of multi-aerosol layers events detected using lidar backscatter profiles is analysed. A good correlation between in situ aerosol extinction coefficient and aerosol optical depth (AOD) measured by the Aerosol Robotic Network (AERONET) sun photometer is observed with a correlation coefficient around 0.80, indicating that the in situ measurements station is representative of the overall atmospheric column. After filtering for multilayer cases and correcting for each layer optical contribution (ML and FT), the atmospheric structure seems to be the main factor influencing the comparison between the two measurement techniques. When the site lies in the ML, the in situ extinction represents 45 % of the sun photometer ML extinction while when the site lies within the FT, the in situ extinction is more than 2 times higher than the FT sun photometer extinction. Moreover, the assumption of a decreasing linear vertical aerosol profile in the whole atmosphere has been tested, significantly improving the instrumental agreement. Remote sensing retrievals of the aerosol particle size distributions (PSDs) from the sun photometer observations are then compared to the near-surface in situ measurements, at dry and at ambient relative humidities. When in situ measurements are considered at dry state, the in situ fine mode diameters are 44 % higher than the sun-photometer-retrieved diameters and in situ volume concentrations are 20 % lower than those of the sun-photometer-retrieved fine mode concentration. Using a parameterised hygroscopic growth factor applied to aerosol diameters, the difference between in situ and retrieved diameters grows larger. Coarse mode in situ diameters and concentrations show a good correlation with retrieved PSDs from remote sensing.
Enhanced representation of soil NO emissions in the Community Multiscale Air Quality (CMAQ) model version 5.0.2
Authors: Rasool Quazi Z. , Zhang Rui , Lash Benjamin , Cohan Daniel S. , Cooter Ellen J. , Bash Jesse O. , Lamsal Lok N. 
Published: September 2016

Abstract. Modeling of soil nitric oxide (NO) emissions is highly uncertain and may misrepresent its spatial and temporal distribution. This study builds upon a recently introduced parameterization to improve the timing and spatial distribution of soil NO emission estimates in the Community Multiscale Air Quality (CMAQ) model. The parameterization considers soil parameters, meteorology, land use, and mineral nitrogen (N) availability to estimate NO emissions. We incorporate daily year-specific fertilizer data from the Environmental Policy Integrated Climate (EPIC) agricultural model to replace the annual generic data of the initial parameterization, and use a 12 km resolution soil biome map over the continental USA. CMAQ modeling for July 2011 shows slight differences in model performance in simulating fine particulate matter and ozone from Interagency Monitoring of Protected Visual Environments (IMPROVE) and Clean Air Status and Trends Network (CASTNET) sites and NO2 columns from Ozone Monitoring Instrument (OMI) satellite retrievals. We also simulate how the change in soil NO emissions scheme affects the expected O3 response to projected emissions reductions.
ICESat laser altimetry over small mountain glaciers
Authors: Treichler Désirée , Kääb Andreas 
Published: September 2016

Abstract. Using sparsely glaciated southern Norway as a case study, we assess the potential and limitations of ICESat laser altimetry for analysing regional glacier elevation change in rough mountain terrain. Differences between ICESat GLAS elevations and reference elevation data are plotted over time to derive a glacier surface elevation trend for the ICESat acquisition period 2003–2008. We find spatially varying biases between ICESat and three tested digital elevation models (DEMs): the Norwegian national DEM, SRTM DEM, and a high-resolution lidar DEM. For regional glacier elevation change, the spatial inconsistency of reference DEMs – a result of spatio-temporal merging – has the potential to significantly affect or dilute trends. Elevation uncertainties of all three tested DEMs exceed ICESat elevation uncertainty by an order of magnitude, and are thus limiting the accuracy of the method, rather than ICESat uncertainty. ICESat matches glacier size distribution of the study area well and measures small ice patches not commonly monitored in situ. The sample is large enough for spatial and thematic subsetting. Vertical offsets to ICESat elevations vary for different glaciers in southern Norway due to spatially inconsistent reference DEM age. We introduce a per-glacier correction that removes these spatially varying offsets, and considerably increases trend significance. Only after application of this correction do individual campaigns fit observed in situ glacier mass balance. Our correction also has the potential to improve glacier trend significance for other causes of spatially varying vertical offsets, for instance due to radar penetration into ice and snow for the SRTM DEM or as a consequence of mosaicking and merging that is common for national or global DEMs. After correction of reference elevation bias, we find that ICESat provides a robust and realistic estimate of a moderately negative glacier mass balance of around −0.36 ± 0.07 m ice per year. This regional estimate agrees well with the heterogeneous but overall negative in situ glacier mass balance observed in the area.
Zika Virus Infection in Pregnancy, Microcephaly, and Maternal and Fetal Health: What We Think, What We Know, and What We Think We Know
Authors: Alvarado Maria Gabriela , Schwartz David A. 
Published: September 2016

Context.—The global epidemic of Zika virus (ZIKV) infection has emerged as an important public health problem affecting pregnant women and their infants.
Objectives.—To review the causal association between ZIKV infection during pregnancy and intrauterine fetal infection, microcephaly, brain damage, congenital malformation syndrome, and experimental laboratory models of fetal infection. Many questions remain regarding the risk factors, pathophysiology, epidemiology, and timing of maternal-fetal transmission and disease. These include mechanisms of fetal brain damage and microcephaly; the role of covariables, such as viral burden, duration of viremia, and host genetics, on vertical transmission; and the clinical and pathologic spectrum of congenital Zika syndrome. Additional questions include defining the potential long-term physical and neurobehavioral outcomes for infected infants, whether maternal or fetal host genetics influence the clinical outcome, and whether ZIKV infection can cause maternal morbidity. Finally, are experimental laboratory and animal models of ZIKV infection helpful in addressing maternal-fetal viral transmission and the development of congenital microcephaly? This communication provides current information and attempts to address some of these important questions.
Data Sources.—Comprehensive review of published scientific literature.
Conclusions.—Recent advances in epidemiology, clinical medicine, pathology, and experimental studies have provided a great amount of new information regarding vertical ZIKV transmission and the mechanisms of congenital microcephaly, brain damage, and congenital Zika syndrome in a relatively short time. However, much work still needs to be performed to more completely understand the maternal and fetal aspects of this new and emerging viral disease.
Dynamique spatiale d’un espace à caractère steppique : le cas des Hautes Plaines sud-oranaises (Algérie)
Authors: Hadeid Mohamed , Bendjelid Abed , Fontaine Jacques , Ormaux Serge 
Published: September 2016

Les Hautes Plaines steppiques sud-oranaises représentent un milieu biogéographique ouvert et fragile. Pendant des siècles, le nomadisme pastoral en a été l’unique forme d’exploitation. La colonisation provoque une première rupture en réduisant les mouvements des tribus, brisant ainsi la complémentarité spatiale existante entre la Steppe et le Tell. Après l’indépendance, l’État algérien reprend certaines dispositions du pouvoir colonial, mais avec une volonté de développement et d’intégration de la Steppe à l’espace national. La population, encore majoritairement nomade dans les années 1960, se sédentarise rapidement devant les « bienfaits de la modernité ». Durant les années 1980, l’État se lance dans une politique de mise en valeur agricole conduisant la Steppe à la perte de sa vocation strictement pastorale. Cette nouvelle forme de mise en valeur, ainsi que la forte augmentation de la population ont entraîné une profonde restructuration spatiale.