bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hyper‐Assembly of Self‐Assembled Glycoclusters Mediated by Specific Carbohydrate–Carbohydrate Interactions
Authors: Yan Gengwei , Yamaguchi Takumi , Suzuki Tatsuya , Yanaka Saeko , Sato Sota , Fujita Makoto , Kato Koichi 
Published: March 2017

AbstractHybridization of a self‐assembled, spherical complex with oligosaccharides containing Lewis X, a functional trisaccharide displayed on various cell surfaces, yielded well‐defined glycoclusters. The self‐assembled glycoclusters exhibited homophilic hyper‐assembly in aqueous solution in a Ca2+‐dependent manner through specific carbohydrate–carbohydrate interactions, offering a structural scaffold for functional biomimetic systems.
Stabilization of a Heat‐ODE System Cascaded at a Boundary Point and an Intermediate Point
Authors: Zhen Zhiyuan , Tang Shu‐Xia , Zhou Zhongcheng 
Published: March 2017

AbstractThis paper considers the stabilization of a heat‐ODE system cascaded at a boundary point and an intermediate point. The stabilizing feedback control law is designed by the backstepping method. Based on a novel transformation, we prove that all the kernel functions in the forward and inverse transformations are of the class C2. Moreover, the effectiveness of controller design is shown with a numerical simulation. Finally, we show the coherence between the controllability assumption of the main theorem in this paper and the known one for a special case with λ=0.
Correlation between the potency of flavonoids for cytochrome c reduction and inhibition of cardiolipin‐induced peroxidase activity
Authors: Lagoa Ricardo , Samhan‐Arias Alejandro K. , Gutierrez‐Merino Carlos 
Published: March 2017

AbstractThere are large differences between flavonoids to protect against apoptosis, a process in which cytochrome c (Cyt c) plays a key role. In this work, we show that 7 of 13 flavonoids studied have a capacity to reduce Cyt c similar or higher than ascorbate, the flavonols quercetin, kaempferol and myricetin, flavanol epigallocatechin‐gallate, anthocyanidins cyanidin and malvidin, and the flavone luteolin. In contrast, the kaempferol 3(O)‐ and 3,4′(O)‐methylated forms, the flavanone naringenin, and also apigenin and chrysin, had a negligible reducing capacity. Equilibrium dialysis and quenching of 1,6‐diphenyl‐1,3,5‐hexatriene fluorescence experiments showed that flavonoids did not interfere with Cyt c binding to cardiolipin (CL)/phosphatidylcholine (PC) vesicles. However, the CL‐induced loss of Cyt c Soret band intensity was largely attenuated by flavonoids, pointing out a stabilizing action against Cyt c unfolding in the complex. Moreover, flavonoids that behave as Cyt c reductants also inhibited the pro‐apoptotic CL‐induced peroxidase activity of Cyt c, indicating that modulation of Cyt c signaling are probable mechanisms behind the protective biological activities of flavonoids. © 2016 BioFactors, 43(3):451–468, 2017
Dienophile‐Modified Mannosamine Derivatives for Metabolic Labeling of Sialic Acids: A Comparative Study
Authors: Dold Jeremias E. G. A. , Pfotzer Jessica , Späte Anne‐Katrin , Wittmann Valentin 
Published: March 2017

AbstractSialic acids play an important role in numerous cell adhesion processes, and sialylation levels are known to be altered under certain pathogenic conditions, such as cancer. Metabolic glycoengineering with mannosamine derivatives is a convenient way to introduce non‐natural chemical reporter groups into sialylated glycoconjugates, offering the opportunity to label sialic acids by using bioorthogonal ligation chemistry. The labeling intensity depends not only on the rate of the ligation reaction but also on the extent to which the natural sialic acids are replaced by the modified ones; that is, the incorporation efficiency. Here, we present a comparative study of eight mannosamine derivatives featuring terminal alkenes as chemical reporter groups that can be labeled by an inverse‐electron‐demand Diels–Alder (DAinv) reaction. The derivatives differed in chain length as well as the type of linkage (carbamates, amides, and a urea) that connects the terminal alkene to the sugar. As a general trend, increasing chain lengths resulted in higher DAinv reactivity and, at the same time, reduced incorporation efficiency. Carbamates were better accepted than amides with the same chain length; nevertheless, the latter resulted in more intense cell‐surface staining, visible by live‐cell fluorescence microscopy. A urea derivative was also shown to be accepted.
Silencing of ATF2 inhibits growth of pancreatic cancer cells and enhances sensitivity to chemotherapy
Authors: Li Mu , Wu Xingda , Liu Ning , Li Xiaoying , Meng Fanbin , Song Shaowei 
Published: March 2017

AbstractPancreatic cancer is one of the leading causes of cancer‐related death worldwide. Activating transcription factor 2 (ATF2) is a multifunctional transcription factor, and is implicated in tumor progress, yet its role in pancreatic cancer remains unclear. In the present study, the level of ATF2 in pancreatic cancer tissues and the adjacent non‐tumorous tissues was detected by quantitative real‐time PCR and Western blot. The roles of ATF2 in the proliferation, cell cycle, and apoptosis of pancreatic cancer cells were investigated through ATF2 silencing, and the effect of ATF2 shRNA on the sensitivity of pancreatic cancer cells to gemcitabine, an anti‐tumor drug, was explored. The results of our study showed that the ATF2 level in the pancreatic cancer tissues was higher than that in the adjacent non‐tumorous tissues. Silencing of ATF2 was found to inhibit proliferation, arrest cell cycle at G1 phase and induce apoptosis in pancreatic cancer cells. Moreover, ATF2 silencing enhanced gemcitabine‐induced growth‐inhibition and apoptosis‐induction effects in pancreatic cancer cells. In summary, silencing of ATF2 inhibited the growth of pancreatic cancer cells and enhanced the anti‐tumor effects of gemcitabine, suggesting that ATF2 plays a pro‐survival role in pancreatic cancer. Our results also propose that a high level of ATF2 may serve as a potential biomarker of pancreatic cancer, and that ATF2 may become a potential target for anti‐tumor therapy.
Effect of coronary dominance on 2‐year outcomes after percutaneous coronary intervention in patients with acute coronary syndrome
Authors: He Chen , Ma Yuan‐Liang , Wang Chuang‐Shi , Song Ying , Tang Xiao‐Fang , Zhao Xue‐Yan , Gao Run‐Lin , Yang Yue‐Jin , Xu Bo , Yuan Jin‐Qing 
Published: March 2017

ObjectivesThis retrospective, single‐center, observational analysis from prospectively collected database evaluated whether left dominance affected the long‐term outcomes of acute coronary syndrome patients undergoing percutaneous coronary intervention, and whether the effect was independent of SYNTAX score.BackgroundLeft dominance is believed to be associated with worse prognoses. The anatomical SYNTAX score is a scoring system based on the complexity and severity of coronary lesions and is thought to be a prognostic tool to predict short‐ and long‐term outcomes. There are few studies about whether the effect of left dominance is independent of SYNTAX score.MethodsBetween January 2013 and December 2013, 6255 consecutive acute coronary syndrome patients who were admitted to Fuwai hospital and underwent percutaneous coronary intervention (PCI) were enrolled in this study. Based on coronary dominance and the calculation methods of the SYNTAX score, patients were divided into a left‐dominant group (LD group; 390 patients) and a right‐dominant or co‐dominant group (RD + Co group, 5865 patients).ResultThe 2‐year mortality rate was significantly higher in the LD group than in the RD + Co group (2.58% vs. 1.23%, P = 0.024). In multivariate Cox analysis, the independent predictors of mortality were coronary dominance, IABP support, age, baseline SYNTAX score, and ejection fraction.ConclusionsLD was an independent predictor of long‐term mortality in ACS patients undergoing PCI. The effect of LD still existed after adjustment for several important variables and was independent of SYNTAX score. © 2017 Wiley Periodicals, Inc.
Biomass‐assisted Zeolite Syntheses as a Tool for Designing New Acid Catalysts
Authors: Louis Benoît , Gomes Elisa S. , Losch Pit , Lutzweiler Gaëtan , Coelho Tiago , Faro Arnaldo , Pinto Joana F. , Cardoso Cristiane S. , Silva Alessandra V. , Pereira Marcelo M. 
Published: March 2017

AbstractThe aim of this Concept article is to highlight different aspects of using biomass residues or extracted molecules in the synthesis of zeolites (mainly), aluminas and layered doubled hydroxides (LDHs). The strategies presented should serve as a basis for rationally preparing those aforementioned materials for catalytic purposes. Indeed, the presence of sugars, lignin, lignocellulosic biomass usually induces morphological/textural changes as well as (in some cases) modified chemical composition and surface properties.
Access to (Hetero)arylated Selenophenes via Palladium‐catalysed Stille, Negishi or Suzuki Couplings or C−H Bond Functionalization Reaction
Authors: Skhiri Aymen , Ben Salem Ridha , Soulé Jean‐François , Doucet Henri 
Published: March 2017

Abstract(Hetero)aryl‐substituted selenophenes exhibit important physical properties especially for optoelectronics. Palladium‐catalysed coupling reactions currently represent the most efficient methods to prepare such (hetero)arylated selenophene derivatives. Initially, Stille coupling was the most efficient reaction for the synthesis of these compounds; however, over the last decade, Suzuki coupling has become the most commonly employed. Recently, Pd‐catalysed arylation via the C−H bond activation of selenophenes has proved to be a very convenient alternative method for the preparation of several arylated selenophenes as there is no need to prepare organometallic derivatives. In this Review, the progress and substrate scope in the synthesis of both C2‐ and C3‐arylated selenophenes via Pd‐catalysis are summarized.
Optical Sensing of Anions via Supramolecular Recognition with Biimidazole Complexes
Authors: Rommel Sebastian A. , Sorsche Dieter , Fleischmann Maximilian , Rau Sven 
Published: March 2017

AbstractPhosphorescent metal complexes with peripheral N‐H donor functionalities have attracted great attention as potential molecular sensing units for anionic species lately. In this contribution we discuss the development and potential of anion recognition and sensing features of recent examples of luminescent 2,2′‐biimidazole complexes of ruthenium(II), iridium(III), osmium(II) and cobalt(III). The general dependency of photophysical features in these complexes regarding the acid‐base chemistry of the peripheral N‐H functionalities will be outlined as a basic requirement for optical ion recognition. Systematic strategies for the tuning and specific improvement by synthetic means will be discussed regarding recent reports. With respect to their distinct photophysical features, different transition metals are considered individually to demonstrate particular trends regarding ligand modification within the respective groups. In summary, this review elucidates the current state‐of‐the‐art and future potential of the versatile class of 2,2′‐biimidazole based sensor chromophores.
Ultra‐Narrow Low‐Bandgap Graphene Nanoribbons from Bromoperylenes—Synthesis and Terahertz‐Spectroscopy
Authors: Jänsch Daniel , Ivanov Ivan , Zagranyarski Yulian , Duznovic Ivana , Baumgarten Martin , Turchinovich Dimitry , Li Chen , Bonn Mischa , Müllen Klaus 
Published: March 2017

AbstractSoluble ultra‐narrow armchair graphene nanoribbons (AGNRs) with length of ≈20 nm and completely fused cores exceeding 5 nm in length, pronounced near‐infrared (NIR) absorption up to 1400 nm, and a low band gap (≈0.9 eV) are synthesized from 3,9(3,10)‐dibromoperylene and 3,4,9,10‐tetrabromoperylene. Since the monomers are obtained from perylene carboxyanhydrides, a remarkable link between dye and graphene chemistry is established. The two‐step protocol for the AGNR synthesis by aryl–aryl coupling and subsequent cyclodehydrogenation is compared with a direct Yamamoto polymerization. Ultrafast photoconductivity analysis by optical pump‐terahertz (THz) probe spectroscopy of the longest AGNRs excited in the NIR regime (800 nm) reveal their high intrinsic charge carrier mobility.
Defective Metal–Organic Frameworks Incorporating Iridium‐Based Metalloligands: Sorption and Dye Degradation Properties
Authors: Fan Kun , Nie Wei‐Xuan , Wang Lu‐Ping , Liao Chwen‐Haw , Bao Song‐Song , Zheng Li‐Min 
Published: March 2017

AbstractArtificial control and engineering of metal–organic framework (MOF) crystals with defects can endow them with suitable properties for applications in gas storage, separation, and catalysis. A series of defective iridium‐containing MOFs, [Zn4(μ4‐O)(Ir‐A)2(1−x)(Ir‐B)2x] (ZnIr‐MOF‐dx), were synthesized by doping heterostructured linker Ir‐BH3 into the parent [Zn4(μ4‐O)(Ir‐A)2] (ZnIr‐MOF), in which Ir‐AH3 represents [Ir(ppy‐COOH)3] (ppyCOOH=3‐(pyridin‐2‐yl)benzoic acid) and Ir‐BH3 is [Ir(ppy‐COOH)2(2‐pyPO3H)] (2‐pyPO3H2=2‐pyridylphosphonic acid). Samples with different degrees of defects were characterized by SEM, IR and NMR spectroscopy, powder XRD measurements, and thermal and elemental analyses. ZnIr‐MOF‐d0.3 was selected as a representative for gas (N2, CO2) or vapor (H2O, alcohol) sorption studies. The results demonstrate that defective ZnIr‐MOF‐d0.3 possesses multiple pore size distributions, ranging from micro‐ to mesopores, unlike the parent material, which shows a uniform micropore distribution. The hydrophilicity of the interior surface is also increased after defect engineering. As a result, ZnIr‐MOF‐d0.3 shows an enhanced adsorption capability toward n‐butanol, relative to that of the parent compound. Optical studies reveal that both ZnIr‐MOF and ZnIr‐MOF‐d0.3 have low band gaps (2.35 and 2.40 eV), corresponding to semiconductors. ZnIr‐MOF‐d0.3 exhibits dramatically increased photocatalytic efficiency for dye degradation.
Cover Picture: Silver‐Catalyzed Cascade Radical Cyclization for Stereoselective Synthesis of Exocyclic Phosphine Oxides (Chin. J. Chem. 3/2017)
Authors: Mao Liuliang , Li Yonghong , Yang Shangdong 
Published: March 2017

The cover picture shows a concise and effective protocol for the synthesis of valuable exocyclic phosphine oxides via the process of free radical cascade cyclization. Waterwheel in series shows the implied meaning in the process of phosphorylation/ cascade cyclization of various 1,6‐dienes involving the C—P and C—C bonds formation. More details are discussed in the article by Yang et al. on page 316–322.
image
From Trash to Treasure: Turning Air Pollutants into Materials for Energy Storage
Authors: Liang Jiachen , Zhang Chen , Liu Donghai , Zhang Lina , Ling Guowei , Yang Quan‐Hong 
Published: March 2017

AbstractEnvironmental and energy issues are hot topics in the sustainable development of our planet. Air pollution, as a vital environmental issue, has puzzled us for decades, and a green and economical approach to control air pollutants is urgently required. New energy‐storage techniques have emerged as fascinating routes to reduce potential environmental problems. Therefore, the combination of air pollutants with energy‐storage devices is an appealing solution for air pollution. Herein, the principles of recovering air pollutants for use in energy‐storage materials are proposed, including their direct use as active materials, their conversion into active materials, and their use as dopants to modify the electrode. Typical air pollutants are selected to demonstrate their potential use in green energy storage. Future prospects of the broad application of air pollutants in energy‐related fields are also commented on.
An Intrinsic Self‐Charging Biosupercapacitor Comprised of a High‐Potential Bioanode and a Low‐Potential Biocathode
Authors: Alsaoub Sabine , Ruff Adrian , Conzuelo Felipe , Ventosa Edgar , Ludwig Roland , Shleev Sergey , Schuhmann Wolfgang 
Published: March 2017

AbstractAn intrinsic self‐charging biosupercapacitor built on a unique concept for the fabrication of biodevices based on redox polymers is presented. The biosupercapacitor consists of a high‐potential redox polymer based bioanode and a low‐potential redox polymer based biocathode in which the potentials of the electrodes in the discharged state show an apparent potential mismatch Eanode>Ecathode and prevent the use of the device as a conventional biofuel cell. Upon charging, the potentials of the electrodes are shifted to more positive (cathode) and more negative (anode) values because of a change in the aox‐to‐ared ratio within the redox polymer matrix. Hence, a potential inversion occurs in the charged state (Eanode<Ecathode) and an open circuit voltage of >0.4 V is achieved and the biodevice acts as a true biosupercapacitor. The bioanode consists of a novel specifically designed high‐potential Os complex modified polymer for the efficient immobilization and electrical wiring of glucose converting enzymes, such as glucose oxidase and flavin adenine dinucleotide (FAD)‐dependent glucose dehydrogenase. The cathodic side is constructed from a low‐potential Os complex modified polymer integrating the O2 reducing enzyme, bilirubin oxidase. The large potential differences between the redox polymers and the prosthetic groups of the biocatalysts ensure fast and efficient charging of the biodevice.
Composite Electrolyte for All‐Solid‐State Lithium Batteries: Low‐Temperature Fabrication and Conductivity Enhancement
Authors: Lee Sang‐Don , Jung Kyu‐Nam , Kim Hyeongil , Shin Hyun‐Seop , Song Seung‐Wan , Park Min‐Sik , Lee Jong‐Won 
Published: March 2017

AbstractAll‐solid‐state lithium batteries offer notable advantages over conventional Li–ion batteries with liquid electrolytes in terms of energy density, stability, and safety. To realize this technology, it is critical to develop highly reliable solid‐state inorganic electrolytes with high ionic conductivities and adequate processability. Li1+xAlxTi2−x(PO4)3 (LATP) with a NASICON (Na superionic conductor)‐like structure is regarded as a potential solid electrolyte, owing to its high “bulk” conductivity (ca. 10−3 S cm−1) and excellent stability against air and moisture. However, the solid LATP electrolyte still suffers from a low “total” conductivity, mainly owing to the blocking effect of grain boundaries to Li+ conduction. In this study, an LATP–Bi2O3 composite solid electrolyte shows very high total conductivity (9.4×10−4 S cm−1) at room temperature. Bi2O3 acts as a microstructural modifier to effectively reduce the fabrication temperature of the electrolyte and to enhance its ionic conductivity. Bi2O3 promotes the densification of the LATP electrolyte, thereby improving its structural integrity, and at the same time, it facilitates Li+ conduction, leading to reduced grain‐boundary resistance. The feasibility of the LATP–Bi2O3 composite electrolyte in all‐solid‐state Li batteries is also examined in this study.
CdS/Zr:Fe2O3 Nanorod Arrays with Al2O3 Passivation Layer for Photoelectrochemical Solar Hydrogen Generation
Authors: Mahadik Mahadeo A. , Subramanian Arunprabaharan , Chung Hee‐Suk , Cho Min , Jang Jum Suk 
Published: March 2017

AbstractCdS‐sensitized 1 D Zr:Fe2O3 nanorod arrays were synthesized on fluorine‐doped tin oxide substrates by a two‐step hydrothermal method. The photoelectrochemical results demonstrate that the current density (4.2 mA cm−2 at 0 V vs. Ag/AgCl) recorded under illumination for the CdS/1 D Zr:Fe2O3 photoanodes is 2.8 time higher than the bare 1 D Zr:Fe2O3. The extended absorbance spectrum, the reduced recombination, and the effective transport of photogenerated holes in CdS to the electrolyte facilitate enhancement in the photoelectrochemical performance. From X‐ray photoelectron spectroscopy and TEM observations of the bare and aluminum oxide‐treated CdS/1 D Zr:Fe2O3 photoanodes, we could confirm that the 1 D Zr:Fe2O3 nanorods were covered by the CdS layer and Al2O3 layer present on surface of CdS. Furthermore, the photocurrent and stability of the CdS/1 D Zr:Fe2O3 nanorods was significantly enhanced by Al2O3 compared to bare CdS/1 D Zr:Fe2O3 heterojunction owing to its ability to act as an effective holetransport‐ as well as photocorrosion‐protecting layer. These remarkable enhancements in light‐energy harvesting, improvement in charge transport, and stability directly suggest the usefulness of photoanodes for solar hydrogen generation.
Designing Squaraines to Control Charge Injection and Recombination Processes in NiO‐based Dye‐Sensitized Solar Cells
Authors: Langmar Oliver , Saccone Davide , Amat Anna , Fantacci Simona , Viscardi Guido , Barolo Claudia , Costa Rubén D. , Guldi Dirk M. 
Published: March 2017

AbstractHerein, the synthesis of a new family of squaraines (SQs) and their application in p‐type dye‐sensitized solar cells (DSSCs) is presented. In particular, two sets of SQs were designed featuring either two or four anchoring carboxylic groups combined with either oxygen or dicyanovinyl central groups. The SQs were characterized by using a joint theoretical, photophysical, and electrochemical approach. Importantly, the presence of different central groups forces a frozen cis (dicyanovinyl group) or a trans (oxygen group) SQ conformation. Based on the latter, the current work enables a direct comparison between cis and trans isomers as well as the impact of a different number of anchors. Considering their electron‐accepting and light‐harvesting character, they were tested in NiO‐based DSSCs. Photocurrent–voltage, incident photon‐to‐current conversion efficiency (IPCE), and electrochemical impedance spectroscopy measurements were performed. By virtue of their different symmetry, stereochemistry, and number of carboxylic groups, altered adsorption behavior onto NiO electrodes as well as diverse charge injection and charge recombination dynamics were noted under operation conditions. SQs with four linkers in a frozen cis isomerism show the best charge collection properties among the investigated SQs, providing a valuable guideline for the molecular design of future SQs for p‐type DSSCs. In addition, we assembled tandem DSSCs featuring SQ/NiO photocathodes and N719/TiO2 photoanodes. The IPCE of the resulting tandem DSSCs implies light harvesting throughout most of the visible part of the solar spectrum owing to the complementary absorption features of SQ and N719.
Metal Doping to Enhance the Photoelectrochemical Behavior of LaFeO3 Photocathodes
Authors: Díez‐García María Isabel , Gómez Roberto 
Published: March 2017

AbstractThe development of tandem devices for water photosplitting requires the preparation of photocathodic materials based on earth‐abundant elements that show long‐term stability in aqueous electrolytes. Ternary metal oxides seem to be a viable option, among which perovskites stand out. In this context, transparent and compact LaFeO3 thin‐film electrodes have been prepared by a sol–gel process, both undoped and doped with metals (M) such as Mg or Zn. Pristine electrodes support the development of cathodic photocurrents in 0.1 m NaOH aqueous solutions, particularly in the presence of oxygen, with an onset potential as high as 1.4 V versus the reversible hydrogen electrode. Doping with Mg or Zn leads to an important enhancement of the photocurrent, which peaks for a stoichiometry of LaFe0.95M0.05O3 with a sixfold enhancement with respect to the pristine material. Such an improvement is attributed to an increase in both the density and mobility of the majority carriers, although a contribution of surface passivation cannot be excluded.