bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reviewer Acknowledgements
Authors: Smith Robert 
Published: January 2017

Journal of Education and Training Studies (JETS) would like to thank the following reviewers for reviewing manuscripts from July 1, 2015, to October 31, 2015. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Redfame Publishing appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Ardi MarwanBaraka M. Ngussa Betsy Diegel Cassandra Smith Charlotte Alverson Davy Seligin Ebrahim Mohammadpour Ebrahim Rahimi Enisa Mede Greg Rickwood Hassan Shaaban Hoi-yung Leung Jayaluxmi Naidoo Jeyavel Sundaramoorthy John Cowan Leann Stadtlander Leonor Thomson Lisa Marie Portugal Marcie Zaharee Michael Baron Min Gui Mu-hsuan Chou Mustafa Çakır R.-L. Etienne Barnett Richard Beresford Richard H. Martin Richard Penny Sahar Younes Othman Seyed Jalal Abdolmanafi Rokni Seyyedeh Mina Hamedi Vasiliki Brinia Veronica Rosa Wang Kin Chiu Robert Smith Editorial Assistant On behalf of, The Editorial Board of Journal of Education and Training Studies Redfame Publishing 9450 SW Gemini Dr. #99416 Beaverton, OR 97008, USA URL: http://jets.redfame.com
Reviewer Acknowledgements
Authors: Smith Robert 
Published: January 2017

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue. Reviewers for Volume 4, Number 12 Anne M. Hornak Baraka M. Ngussa Cagla Atmaca Carmen PérezSabater Cynthia M. Compton Damodar Khanal Elena Jerves Intakhab Khan Jill M. Feldman Leila Youssef Lorna T. Enerva Marcie Zaharee Meral Şeker Min Gui Mustafa Çakır Niveen M. Zayed Richard H. Martin Sahar Younes Othman Samad Mirza Suzani Seyyedeh Mina Hamedi Suzan Kavanoz Wang Kin Chiu Yalçın Dilekli Yerlan Seisenbekov Yi Lu Zanele Ndlovu Robert Smith Editorial Assistant On behalf of, The Editorial Board of Journal of Education and Training Studies Redfame Publishing 9450 SW Gemini Dr. #99416 Beaverton, OR 97008, USA URL: http://jets.redfame.com
Reviewer Acknowledgements
Authors: Smith Robert 
Published: January 2017

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue. Reviewers for Volume 4, Number 4 Ardi Marwan Chris Prince Udochukwu Njoku Damodar Khanal David A. Compton Enisa Mede Erickzon Astorga Hoi-yung Leung Jayaluxmi Naidoo John Cowan Laima Kyburiene Lisa Marie Portugal Lorna Enerva Mahmoud Radwan Marieke van der Schaaf Min Gui Mu-hsuan Chou Mustafa Çakır Puneet S. Gill Richard Beresford Richard H. Martin Richard Penny Sahar Younes Othman Sandra Kaplan Seyyedeh Mina Hamedi Torok Marianna Wang Kin Chiu Yerlan Seisenbekov Robert Smith Editorial Assistant On behalf of, The Editorial Board of Journal of Education and Training Studies Redfame Publishing 9450 SW Gemini Dr. #99416 Beaverton, OR 97008, USA URL: http://jets.redfame.com
Reviewer Acknowledgements
Authors: Walter Andrew 
Published: January 2017

Studies in Engineering and Technology (SET) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether SET publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue. Reviewers for Volume 3, Number 1 Ahmet Can Altunişik Alexander Russell Arnaud Duchosal Girish Upreti Hassan Shaaban Hossam Zaqoot Isaac Atuahene KaiLong Hsiao Lei Kang Loc Nguyen Marco A Ruano S. Haddout Saminda Dharmarathna Wael Salah Wolday Abrha Yao Liu Yi Zheng Andrew Walter Editorial Assistant On behalf of, The Editorial Board of Studies in Engineering and Technology Redfame Publishing 9450 SW Gemini Dr. #99416 Beaverton, OR 97008, USA URL: http://set.redfame.com
Reviewer Acknowledgements
Authors: Johnson Patricia 
Published: January 2017

Studies in Media and Communication (SMC) would like to thank the following reviewers for reviewing manuscripts from October 9, 2012, to May 1, 2013. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether SMC publishes their work, appreciate the helpful feedback provided by the reviewers. Redfame Publishing appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Philemon Bantimaroudis Mark Stuhlfaut Antonio García Gómez Camelia Cmeciu Dorina Ticu Ann Grand Yi Guo Jenny-Ann Danell Millaray Salas Mireia Farrús Jo Verhoeven
Reviewer Acknowledgements
Authors: Johnson Patricia 
Published: January 2017

Studies in Media and Communication (SMC) would like to thank the following reviewers for reviewing manuscripts from June 1, 2015, to November 30, 2015. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether SMC publishes their work, appreciate the helpful feedback provided by the reviewers. Redfame Publishing appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Anastasia Stamou Begoña Montero-Fleta Bernard Naledzani Rasila Camelia Cmeciu Carmen Pérez-Sabater Christos Giannoulis Diego Santos Vieira de Jesus Jenny-Ann Danell Katerina Diamantaki Kunle Olufemi Aramide Millaray Salas Simone Tosoni Young Joon Lim Patricia JohnsonEditorial Assistant On behalf of, The Editorial Board of Studies in Media and Communication Redfame Publishing 9450 SW Gemini Dr. #99416 Beaverton, OR 97008, USA URL: http://smc.redfame.com
The Acinetobacter Outer Membrane Contains Multiple Specific Channels for Carbapenem β-Lactams as Revealed by Kinetic Characterization Analyses of Imipenem Permeation into Acinetobacter baylyi Cells
Authors: Morán-Barrio Jorgelina , Cameranesi María M. , Relling Verónica , Limansky Adriana S. , Brambilla Luciano , Viale Alejandro M. 
Published: January 2017

ABSTRACT

The number and type of outer membrane (OM) channels responsible for carbapenem uptake in
Acinetobacter
are still not well defined. Here, we addressed these questions by using
Acinetobacter baylyi
as a model species and a combination of methodologies aimed to characterize OM channels in their original membrane environment. Kinetic and competition analyses of imipenem (IPM) uptake by
A. baylyi
whole cells allowed us to identify different carbapenem-specific OM uptake sites. Comparative analyses of IPM uptake by
A. baylyi
wild-type (WT) cells and Δ
carO
mutants lacking CarO indicated that this OM protein provided a carbapenem uptake site displaying saturable kinetics and common binding sites for basic amino acids compatible with a specific channel. The kinetic analysis uncovered another carbapenem-specific channel displaying a somewhat lower affinity for IPM than that of CarO and, in addition, common binding sites for basic amino acids as determined by competition studies. The use of
A. baylyi
gene deletion mutants lacking OM proteins proposed to function in carbapenem uptake in
Acinetobacter baumannii
indicated that CarO and OprD/OccAB1 mutants displayed low but consistent reductions in susceptibility to different carbapenems, including IPM, meropenem, and ertapenem. These two mutants also showed impaired growth on
l
-Arg but not on other carbon sources, further supporting a role of CarO and OprD/OccAB1 in basic amino acid and carbapenem uptake. A multiple-carbapenem-channel scenario may provide clues to our understanding of the contribution of OM channel loss or mutation to the carbapenem-resistant phenotype evolved by pathogenic members of the
Acinetobacter
genus.
Full-Genome Sequencing Identifies in the Genetic Background Several Determinants That Modulate the Resistance Phenotype in Methicillin-Resistant Staphylococcus aureus Strains Carrying the Novel
mecC
Gene
Authors: Milheiriço Catarina , de Lencastre Hermínia , Tomasz Alexander 
Published: January 2017

ABSTRACT

Most methicillin-resistant
Staphylococcus aureus
(MRSA) strains are resistant to beta-lactam antibiotics due to the presence of the
mecA
gene, encoding an extra penicillin-binding protein (PBP2A) that has low affinity for virtually all beta-lactam antibiotics. Recently, a new resistance determinant—the
mecC
gene—was identified in
S. aureus
isolates recovered from humans and dairy cattle. Although having typically low MICs to beta-lactam antibiotics, MRSA strains with the
mecC
determinant are also capable of expressing high levels of oxacillin resistance when in an optimal genetic background. In order to test the impact of extensive beta-lactam selection on the emergence of
mecC
-carrying strains with high levels of antibiotic resistance, we exposed the prototype
mecC
-carrying MRSA strain, LGA251, to increasing concentrations of oxacillin. LGA251 was able to rapidly adapt to high concentrations of oxacillin in growth medium. In such laboratory mutants with increased levels of oxacillin resistance, we identified mutations in genes with no relationship to the
mecC
regulatory system, indicating that the genetic background plays an important role in the establishment of the levels of oxacillin resistance. Our data also indicate that the stringent stress response plays a critical role in the beta-lactam antibiotic resistance phenotype of MRSA strains carrying the
mecC
determinant.
Identification and Characterization of MicroRNA Differentially Expressed in Macrophages Exposed to Porphyromonas gingivalis Infection
Authors: Huck Olivier , Al-Hashemi Jacob , Poidevin Laetitia , Poch Olivier , Davideau Jean-Luc , Tenenbaum Henri , Amar Salomon 
Published: January 2017

ABSTRACTMicroRNAs (miRNAs) are short, noncoding RNAs involved in the regulation of several processes associated with inflammatory diseases and infection. Bacterial infection modulates miRNA expression to subvert any innate immune response. In this study we analyzed, using microarray analysis, the bacterial modulation of miRNAs in bone marrow-derived macrophages (BMMs) in which activity was induced by infection withPorphyromonas gingivalis. The expression of several miRNAs was modulated 3 h postinfection (at a multiplicity of infection of 25). A bioinformatic analysis was performed to further identify pathways related to the innate immune host response under the influence of selected miRNAs. To assess the effects of the miRNAs identified on cytokine secretion (tumor necrosis factor alpha [TNF-α] and interleukin-10 [IL-10]), BMMs were transfected with selected miRNA mimics and inhibitors. Transfection with mmu-miR-155 and mmu-miR-2137 did not modify TNF-α secretion, while their inhibitors increased it. Inhibitors of mmu-miR-2137 and mmu-miR-7674 increased the secretion of the anti-inflammatory factor IL-10. InP. gingivalis-infected BMMs, mmu-miR-155-5p significantly decreased TNF-α secretion while inhibitor of mmu-miR-2137 increased IL-10 secretion.In vivo, in a mouse model ofP. gingivalis-induced calvarial bone resorption, injection of mmu-miR-155-5p or anti-mmu-miR-2137 reduced the size of the lesion significantly. Furthermore, anti-mmu-miR-2137 significantly reduced inflammatory cell infiltration, osteoclast activity, and bone loss. Bioinformatic analysis demonstrated that pathways related to cytokine- and chemokine-related pathways but also osteoclast differentiation may be involved in the effects observed. This study contributes further to our understanding ofP. gingivalis-induced modulation of miRNAs and their physiological effects. It highlights the potential therapeutic merits of targeting mmu-miR-155-5p and mmu-miR-2137 to control inflammation induced byP. gingivalisinfection.
Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial Surface
Authors: Dowdell Alexander S. , Murphy Maxwell D. , Azodi Christina , Swanson Selene K. , Florens Laurence , Chen Shiyong , Zückert Wolfram R. 
Published: January 2017

ABSTRACT

The Lyme disease spirochete
Borrelia burgdorferi
is unique among bacteria in its large number of lipoproteins that are encoded by a small, exceptionally fragmented, and predominantly linear genome. Peripherally anchored in either the inner or outer membrane and facing either the periplasm or the external environment, these lipoproteins assume varied roles. A prominent subset of lipoproteins functioning as the apparent linchpins of the enzootic tick-vertebrate infection cycle have been explored as vaccine targets. Yet, most of the
B. burgdorferi
lipoproteome has remained uncharacterized. Here, we comprehensively and conclusively localize the
B. burgdorferi
lipoproteome by applying established protein localization assays to a newly generated epitope-tagged lipoprotein expression library and by validating the obtained individual protein localization results using a sensitive global mass spectrometry approach. The derived consensus localization data indicate that 86 of the 125 analyzed lipoproteins encoded by
B. burgdorferi
are secreted to the bacterial surface. Thirty-one of the remaining 39 periplasmic lipoproteins are retained in the inner membrane, with only 8 lipoproteins being anchored in the periplasmic leaflet of the outer membrane. The localization of 10 lipoproteins was further defined or revised, and 52 surface and 23 periplasmic lipoproteins were newly localized. Cross-referencing prior studies revealed that the borrelial surface lipoproteome contributing to the host-pathogen interface is encoded predominantly by plasmids. Conversely, periplasmic lipoproteins are encoded mainly by chromosomal loci. These studies close a gap in our understanding of the functional lipoproteome of an important human pathogen and set the stage for more in-depth studies of thus-far-neglected spirochetal lipoproteins.

IMPORTANCE
The small and exceptionally fragmented genome of the Lyme disease spirochete
Borrelia burgdorferi
encodes over 120 lipoproteins. Studies in the field have predominantly focused on a relatively small number of surface lipoproteins that play important roles in the transmission and pathogenesis of this global human pathogen. Yet, a comprehensive spatial assessment of the entire borrelial lipoproteome has been missing. The current study newly identifies 52 surface and 23 periplasmic lipoproteins. Overall, two-thirds of the
B. burgdorferi
lipoproteins localize to the surface, while outer membrane lipoproteins facing the periplasm are rare. This analysis underscores the dominant contribution of lipoproteins to the spirochete's rather complex and adaptable host-pathogen interface, and it encourages further functional exploration of its lipoproteome.
Local glaciation in West Greenland linked to North Atlantic Ocean circulation during the Holocene
Authors: Schweinsberg Avriel D. , Briner Jason P. , Miller Gifford H. , Bennike Ole , Thomas Elizabeth K. 
Published: January 2017

Abstract
Recent observations indicate that ice-ocean interaction drives much of the recent increase in mass loss from the Greenland Ice Sheet; however, the role of ocean forcing in driving past glacier change is poorly understood. To extend the observational record and our understanding of the ocean-cryosphere link, we used a multi-proxy approach that combines new data from proglacial lake sediments, 14C-dated in situ moss that recently emerged from beneath cold-based ice caps, and 10Be ages to reconstruct centennial-scale records of mountain glacier activity for the past ∼10 k.y. in West Greenland. Proglacial lake sediment records and 14C dating of moss indicate the onset of Neoglaciation in West Greenland at ca. 5 ka with substantial snowline lowering and glacier expansion at ca. 3.7 ka followed by additional ice expansion phases at ca. 2.9, ca. 1.7, and ca. 1.4 ka and during the Little Ice Age. We find that widespread glacier growth at ca. 3.7 ka in West Greenland coincides with marked cooling and reduced strength of the West Greenland Current in Disko Bugt. The transition to cooler ocean conditions at ca. 3.7 ka identified in Disko Bugt is registered by marine proxy data farther afield in East Greenland and on the northwestern Icelandic shelf, implying large-scale paleoceanographic changes across the North Atlantic during this interval. The similarity between glacier change on West Greenland and multiple marine and terrestrial records across the North Atlantic suggests that glaciers are strongly influenced by changes in ocean circulation and consequently implies that the ocean-cryosphere teleconnection is a persistent feature of the Arctic system.
Crustal sequestration of magmatic sulfur dioxide
Authors: Mavrogenes John , Blundy Jon 
Published: January 2017

Abstract
Volcanism is responsible for copious discharge of sulfur-bearing magmatic gases. A dominant sulfur-bearing species is SO2, yet sulfite (S4+) minerals are rare in geological settings, testifying to the reactivity of SO2. Disproportionation of SO2 to reduced (sulfide), neutral (elemental sulfur), and oxidized (sulfate) species is one expression of this reactivity. Previous studies of SO2 disproportionation reactions have focused on low-pressure, low-temperature conditions involving SO2 gas and liquid water, such as those close to volcanic vents or in water-free gas systems. However, release of magmatic volatiles in volcanic systems can occur at depth where hot magmatic gas meets crustal rocks ± pore fluids. We investigate the viability of such high-pressure reactions with experiments in which SO2 gas is reacted with a mixture of calcite and a metal-bearing saline fluid at 1.0–1.5 kbar pressure and 400–800 °C. At all temperatures, the calcite-bearing experiments produced anhydrite and sulfide. In the experiment where calcite was replaced by quartz, no sulfide was produced, establishing that Ca is a crucial component of this reaction. We show that extensive production of anhydrite and sulfide through calcite-mediated SO2 disproportionation takes place on time scales of just a few hours. This could occur where hot magmatic SO2 gas encounters magmatic brines in igneous rocks, basinal brines within sedimentary rocks, or calcium-bearing saline groundwaters.
Fossil forest reveals sunspot activity in the early Permian
Authors: Luthardt Ludwig , Rößler Ronny 
Published: January 2017

Abstract
Modern-day periodic climate pattern variations related to solar activity are well known. High-resolution records such as varves, ice cores, and tree-ring sequences are commonly used for reconstructing climatic variations in the younger geological history. For the first time we apply dendrochronological methods to Paleozoic trees in order to recognize annual variations. Large woody tree trunks from the early Permian Fossil Forest of Chemnitz, southeast Germany, show a regular cyclicity in tree-ring formation. The mean ring curve reveals a 10.62 yr cyclicity, the duration of which is almost identical to the modern 11 yr solar cycle. Therefore, we speculate and further discuss that, like today, sunspot activity caused fluctuations of cosmic radiation input to the atmosphere, affecting cloud formation and annual rates of precipitation, which are reflected in the tree-ring archive. This is the earliest record of sunspot cyclicity and simultaneously demonstrates its long-term stable periodicity for at least 300 m.y.
The costs of diabetes among Australians aged 45–64 years from 2015 to 2030: projections of lost productive life years (PLYs), lost personal income, lost taxation revenue, extra welfare payments and lost gross domestic product from Health&WealthMOD2030
Authors: Schofield Deborah , Shrestha Rupendra N , Cunich Michelle M , Passey Megan E , Veerman Lennert , Tanton Robert , Kelly Simon J 
Published: January 2017

ObjectivesTo project the number of people aged 45–64 years with lost productive life years (PLYs) due to diabetes and related costs (lost income, extra welfare payments, lost taxation revenue); and lost gross domestic product (GDP) attributable to diabetes in Australia from 2015 to 2030.DesignA simulation study of how the number of people aged 45–64 years with diabetes increases over time (based on population growth and disease trend data) and the economic losses incurred by individuals and the government. Cross-sectional outputs of a microsimulation model (Health&WealthMOD2030) which used the Australian Bureau of Statistics’ Survey of Disability, Ageing and Carers 2003 and 2009 as a base population and integrated outputs from two microsimulation models (Static Incomes Model and Australian Population and Policy Simulation Model), Treasury's population and labour force projections, and chronic disease trends data.SettingAustralian population aged 45–64 years in 2015, 2020, 2025 and 2030.Outcome measuresLost PLYs, lost income, extra welfare payments, lost taxation revenue, lost GDP.Results18 100 people are out of the labour force due to diabetes in 2015, increasing to 21 400 in 2030 (18% increase). National costs consisted of a loss of $A467 million in annual income in 2015, increasing to $A807 million in 2030 (73% increase). For the government, extra annual welfare payments increased from $A311 million in 2015 to $A350 million in 2030 (13% increase); and lost annual taxation revenue increased from $A102 million in 2015 to $A166 million in 2030 (63% increase). A loss of $A2.1 billion in GDP was projected for 2015, increasing to $A2.9 billion in 2030 attributable to diabetes through its impact on PLYs.ConclusionsIndividuals incur significant costs of diabetes through lost PLYs and lost income in addition to disease burden through human suffering and healthcare costs. The government incurs extra welfare payments, lost taxation revenue and lost GDP, along with direct healthcare costs.