bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of culture conditions for rapid clinical‐scale expansion of human umbilical cord blood‐derived mesenchymal stem cells
Authors: Choi Wankyu , Kwon Soon‐Jae , Jin Hye Jin , Jeong Sang Young , Choi Soo Jin , Oh Wonil , Yang Yoon Sun , Jeon Hong Bae , Jeon Eun Su 
Published: October 2017

AbstractBackgroundMesenchymal stem cells (MSCs) have broad‐spectrum therapeutic effects in various diseases, and thus have many clinical applications. However, it is difficult to produce sufficient numbers of MSCs for clinical use, and improved culture systems are required. Here, we report the effects of calcium (Ca2+) and hypoxia on the proliferation of human umbilical cord blood‐derived MSCs (hUCB‐MSCs). In addition, we determined the optimal conditions of these two factors for the large‐scale culture of hUCB‐MSCs.MethodshUCB‐MSCs were maintained under hypoxic conditions (3% O2) with 1.8 mM Ca2+ during long‐term culture, and their proliferation was evaluated. To characterize the underlying mechanisms, the effects on hypoxia‐inducible factor (HIF)‐1α and the extracellular signal‐regulated kinase (ERK) signaling pathways were investigated. The therapeutic effects in a mouse emphysema model were analyzed and compared with those of naive MSCs.ResultsThe proliferation of Ca2+/hypoxia‐treated hUCB‐MSCs was increased compared with that observed using either calcium or hypoxia culture alone, without loss of stem cell marker expression or differentiation ability. The enhancement of the proliferation capacity of hUCB‐MSCs by the synergistic effects of Ca2+ and hypoxia was dependent on the expression of HIF‐1α and the ERK signaling pathway. The proliferation of Ca2+/hypoxia‐treated hUCB‐MSCs resulted in a delayed senescence phenotype and increased the expression levels of stemness genes such as Oct4 and Nanog compared to those observed in conventional culture conditions. In addition, Ca2+/hypoxia‐treated MSCs transplantation in the mouse emphysema model showed the same therapeutic effects as observed with naive MSCs.ConclusionsThese findings suggest that a Ca2+/hypoxia‐based expansion system has applications for the large‐scale production of MSCs for therapeutic purposes.
Draft genome sequence and characterization of commensal Escherichia coli strain BG1 isolated from bovine gastro-intestinal tract
Authors: Segura Audrey , Auffret Pauline , Klopp Christophe , Bertin Yolande , Forano Evelyne 
Published: October 2017

AbstractEscherichia coli is the most abundant facultative anaerobic bacteria in the gastro-intestinal tract of mammals but can be responsible for intestinal infection due to acquisition of virulence factors. Genomes of pathogenic E. coli strains are widely described whereas those of bovine commensal E. coli strains are very scarce. Here, we report the genome sequence, annotation, and features of the commensal E. coli BG1 isolated from the gastro-intestinal tract of cattle. Whole genome sequencing analysis showed that BG1 has a chromosome of 4,782,107 bp coding for 4465 proteins and 97 RNAs. E. coli BG1 belonged to the serotype O159:H21, was classified in the phylogroup B1 and possessed the genetic information encoding “virulence factors” such as adherence systems, iron acquisition and flagella synthesis. A total of 12 adherence systems were detected reflecting the potential ability of BG1 to colonize different segments of the bovine gastro-intestinal tract. E. coli BG1 is unable to assimilate ethanolamine that confers a nutritional advantage to some pathogenic E. coli in the bovine gastro-intestinal tract. Genome analysis revealed the presence of i) 34 amino acids change due to non-synonymous SNPs among the genes encoding ethanolamine transport and assimilation, and ii) an additional predicted alpha helix inserted in cobalamin adenosyltransferase, a key enzyme required for ethanolamine assimilation. These modifications could explain the incapacity of BG1 to use ethanolamine. The BG1 genome can now be used as a reference (control strain) for subsequent evolution and comparative studies.
Advances in medical adhesives inspired by aquatic organisms’ adhesion
Authors: Park Kyu Ha , Seong Keum-Yong , Yang Seung Yun , Seo Sungbaek 
Published: October 2017

Abstract
In biomedicine, adhesives for hard and soft tissues are crucial for various clinical purposes. However, compared with that under dry conditions, adhesion performance in the presence of water or moisture is dramatically reduced. In this review, representative types of medical adhesives and the challenging aspects of wet adhesion are introduced. The adhesion mechanisms of marine mussels, sandcastle worms, and endoparasitic worms are described, and stemming from the insights gained, designs based on the chemistry of molecules like catechol and on coacervation and mechanical interlocking platforms are introduced in the viewpoint of translating these natural adhesion mechanisms into synthetic approaches.
Clinical course and recommendations for patients after anterior cruciate ligament injury and subsequent reconstruction
Authors: Gokeler Alli , Dingenen Bart , Mouton Caroline , Seil Romain 
Published: October 2017

Almost all athletes who have suffered an anterior cruciate ligament (ACL) injury expect a full return to sports at the same pre-injury level after ACL reconstruction (ACLR). Detailed patient information on the reasonable outcomes of the surgery may be essential to improve patient satisfaction. Pre-operative rehabilitation before ACLR should be considered as an addition to the standard of care to maximise functional outcomes after ACLR. We propose an optimised criterion-based rehabilitation programme within a biopsychosocial framework. No benchmark exists for evaluating return-to-sport (RTS) readiness after ACLR. Therefore, the authors propose a multi-factorial RTS test battery. A combination of both physical and psychological elements should be included in the RTS test battery. There is need for shared decision-making regarding RTS.Cite this article: EFORT Open Rev 2017;2:410-420. DOI: 10.1302/2058-5241.2.170011
Broadcasting the archive in Barcelona: Analysing the side effects of Arte Útil projects
Authors: Estupiñán Gemma Medina , Saviotti Alessandra 
Published: October 2017

Abstract
‘Broadcasting the archive’ is an independent project conceived and curated by us in collaboration with Van Abbemuseum, Middlesbrough Institute of Modern Art (mima) and the Asociación de Arte Útil. The idea arose from the urgency to spread the Arte Útil archive created as a principal source of reference and the core of ‘The Museum of Arte Útil’1 beyond the institution, which hosts the material. Being the initial archive researchers, we started thinking about how to make visible the potentiality that the archive – intended as a tool – has. The project is the first attempt to emancipate usership around the Arte Útil archive through a year touring activity programmes such as workshops, discussions and tours hosted by different organizations in various locations in Europe and United States. This interview will reflect on how ‘Broadcasting the archive’ could be considered as a new methodology to understand the porosity of Arte Útil – intended as a movement – outside and inside the institutional framework, with a particular reference to the programme we developed at Museo d’Art Contemporani de Barcelona (MACBA), in collaboration with the Avalancha collective, Núria Güell, Rubén Santiago and Valentina Maini. We invited them to revisit the conversations we had during the weekend for this journal.
Reviews
Authors: Kaestle Thomas , Roberts Bill , Vickery Jonathan , Hards Lorna , Lopez Lucy , Mead Claire , Brehme Kate , Park Gill 
Published: October 2017

Abstract
Planning Unplanned: Can Art have a Function? Towards a New Function of Art in Society, Barbara Holub and Christine Hohenbüchler (eds) (2015) Vienna: Verlag für Moderne Kunst, 256 pp., ISBN: 9783869840635, p/bk, £30.87
Industry and Intelligence: Contemporary Art Since 1820, Liam Gillick (2016) New York: Columbia University Press, 208 pp., ISBN: 9780231170208, h/bk, £26.00
Production Show 2016–2018: Prototyping/Discovering/Analysing, curated by Ruth Claxton and Gavin Wade, Eastside Projects, Digbeth, Birmingham, 1 October– 10 December 2016
The Birmingham Big Art Project (BBAP), shortlist exhibition, various venues in Birmingham, 2016–17
‘The Hop Project’ by General Public (artists Elizabeth Rowe and Chris Poolman), various venues across Herefordshire, Worcestershire, Birmingham and the Black Country, 2016–17
Human Right, Stephen Willats, Middlesbrough Institute of Modern Art, Middlesbrough, UK, 4 March–4 June 2017
The Present in Drag, 9th Berlin Biennale for Contemporary Art, Berlin, 4 June–18 September 2016
Marie Yates, Works 1971–1979, Richard Saltoun Gallery, Great Titchfield Street, London, 24 June–22 July 2016
Art, politics and the public square: From decoration to declaration!
Authors: Child Danielle 
Published: October 2017

Abstract
The term ‘public art’ has long conjured images of modernist sculpture as baubles for the British new towns or monuments to historical figures. Efforts to revisit the term and reassess its associations have made visible a new heterogeneous public art that engages with space, place and identity in new and diverse ways. Whilst these revisions subvert the traditional idea of public art as creating fixed, permanent structures, what remains in common with the public art of the past is the urban as a suitable site. Adopting Henri Lefebvre’s fluid understanding of the city as an oeuvre, this article looks to the relationship between art, the urban and its material: the social. This article contributes a critical reading of the implied politics of three contemporary public art practices through returning to consider the political figure of the virtuoso (whose historical site is the public square) in Hannah Arendt’s writings and revived in Paolo Virno’s critique of neo-liberalism. Arendt’s understanding of the term is explored in relation to three public art projects: Tahrir Cinema (2011–present), Jennifer Allora and Guillermo Calzadilla’s Chalk (1998–2006) and Suzanne Lacy’s Between the Door and the Street (2013) to propose that these works constitute contemporary political practices within the public realm.
El mandato fundacional y la conformación del cuerpo docente del Instituto Superior del Profesorado “Joaquín V. González” (1976-1983)
Authors: Serrao Paula 
Published: October 2017

El artículo analiza la configuración del conjunto docente que formó parte del área de estudios denominada “de las Argentinas y Americanas”, del Instituto Superior del Profesorado Joaquín V. González, durante el periodo 1976-1983. Centralmente, se reflexiona sobre la relación entre “mandato fundacional” del Profesorado y la procedencia institucional de los docentes del área. La primera parte del trabajo se detiene en la construcción de aquel “mandato fundacional”, y en las tensiones identitarias que el mismo generó a la hora de definir criterios institucionales para la selección docente. La segunda parte, en cambio, indaga sobre las lógicas de acceso a las cátedras durante el período dictatorial. La estabilidad laboral en el cuerpo docente, el irregular funcionamiento de las “adscripciones” y el sistema de “recomendaciones” son los principales temas a tratar. Sobre esta base, el último apartado propone algunas hipótesis orientadas a explicar la acentuada presencia de egresados del Instituto y de la Facultad de Humanidades de la Universidad Nacional de La Plata, en el elenco docente aquí abordado.
A survey of wormholes in Soph. frr. 206–213 R.2
Authors: Iovine Giulio 
Published: October 2017

AbstractThis paper analyses some recurring physical features, such as wormholes on the surface, in a fragmentary papyrus from Oxyrhynchus, P.Oxy. IX 1175 + XVII 2081(b), which partially preserves a lost tragedy by Sophocles, Eurypylus (frr. 206-222 R.
Zwei neue Fragmente zur Eingabe SB XVIII 13099 aus der Trierer Papyrussammlung
Authors: Buckatz Tanja 
Published: October 2017

AbstractFirst Edition of two papyrus fragments in the Trier collection (P.UB Trier S 108-36 and 108-37) which supplement SB XVIII 13099, a petition of a house owner, a woman described as a honey-seller, to Asklepiades the oikonomos of the Arsinoite nome, for enforced collection of outstanding rent (3
Traces of a notarial signature in BGU III 997 – a deliberate removal?
Authors: Vierros Marja 
Published: October 2017

AbstractThis article provides a new reading of a notarial signature in papyrus BGU III 997, a copy of an agoranomic sale from the Ptolemaic period. The signature was not transcribed in the original edition since only traces of it survive and the papyrus seems blank and intact at that place. A closer examination reveals that only the upper layer of the papyrus has been peeled off. How, when, and why the alteration took place, remains unsolved.
«Τhey beat him with bronze files» (UPZ I 7)
Authors: Schram Valérie 
Published: October 2017

AbstractThis article examines the meaning of the word ξυστήρ and points out the different types of «scrapers» it may refer to according to the context. In view of the analogy of form and function between all the tools considered, this study discusses the lexical identification and actual use of specific implements such as the woodworking drawknife.
Tax Collection and Grain Measures in Roman Egpyt
Authors: Reggiani Nicola 
Published: October 2017

AbstractThe article presents the edition of two papyri previoulsly described as P.Fay. 300 (P.Cair. Cat. 10841) and 342 (P.Cair. Cat. 10861). The former is an account of tax (?) collections in kind from Euhemeria involving officers called paralēmptai (“receivers”) or possibly sitoparalēmptai (“grain receivers”); the latter is a tax receipt issued by the sitologoi of Berenikis Aigialou and mentions the special measure standard epaiton.
A Coptic Liturgical Prayer for the Consecration of the Chalice
Authors: Maravela Anastasia , Mihálykó Ágnes T. , Wehus Glenn Ø. 
Published: October 2017

AbstractEdition with philological, theological and liturgical commentary of a Coptic prayer preserved on a papyrus from the seventh or eighth century in the collection of the University of Oslo Library. The prayer, which accompanied the consecration of the wine in the chalice in the presence of already consecrated bread, has a coda in Greek signalling the ensuing oral recitation of the Lord’s Prayer.
An Arabic Receipt on Papyrus
Authors: Younes Khaled M. 
Published: October 2017

AbstractThis paper presents the edition of a short Arabic private legal document. The papyrus, P.Cam. Michaelides B 332 recto, records the receipt of sixty one and a half dīnārs less a sixth. The document dates to the month of Muḥarram of the year 274/May-June 887.
H1N1 influenza induced acute respiratory distress syndrome rescued by extracorporeal membrane oxygenation: A case report
Authors: Rawal Gautam , Kumar Raj , Yadav Sankalp , Sujana R 
Published: October 2017

Abstract
Extracorporeal Membrane Oxygenation (ECMO) is now a recognized revolutionary technology, which has emerged as a life-saving therapeutic option for patients with potentially reversible severe respiratory failure who fail to respond positively with the conventional ventilation therapy. Severe acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality, and ECMO has been proven to increase the survival rates in these patients by improving the gas exchange and thus preventing the further hypoxia and catecholamine induced multi-organ damage. The authors present a case of H1N1 influenza related severe ARDS who was successfully rescued by the early use of ECMO. The authors recommend the early use of ECMO to be incorporated in the management of severe refractory ARDS caused due to a potentially reversible cause.
Noninvasive clinical predictors of portal hypertensive gastropathy in patients with liver cirrhosis
Authors: Mandhwani Rajesh , Hanif Farina M. , Ul Haque Muhammad Manzoor , Wadhwa Rajesh Kumar , Hassan Luck Nasir , Mubarak Muhammad 
Published: October 2017

Abstract

Background and Objectives
Portal hypertensive gastropathy (PHG) is described endoscopically as “mosaic-like appearance” of gastric mucosa with or without the red spots. It can only be diagnosed by upper gastrointestinal (GI) endoscopy. The aim of this study was to determine the diagnostic accuracy of platelet count to spleen diameter ratio (PSR) and right liver lobe diameter to albumin ratio (RLAR) in the detection of PHG using upper GI endoscopy as a gold standard in patients with liver cirrhosis.

Material and Methods
This cross-sectional study was conducted in the Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi. All consecutive patients with ages 18–65 years who were screened using esophagogastroduodenoscopy (EGD) to exclude esophageal varices were enrolled. At the same time, findings related to PHG were noted. After informed consent, all the patients had blood tests including platelet count and albumin and abdominal ultrasound determining spleen diameter and right liver lobe diameter.

Results
Out of 111 patients, 59 (53.15%) were males with a mean age of 44 ± 12.61 years. Rate of PHG was observed in 84.68% (94/111) cases confirmed by EGD. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of PSR were 87.23%, 5.88%, 83.67%, 7.69%, and 74.7%, respectively, and those of RLAR were 28.72%, 70.59%, 84.38%, 15.19%, and 35.14%, respectively.

Conclusion
PSR is better predictor of PHG than RLAR but at the expense of relatively lower specificities and NPV likely because of underlying pathophysiology (portal hypertension) which is similar for esophageal varices, PHG, and ascites.
Polyphenols treatment in patients with nonalcoholic fatty liver disease
Authors: Abenavoli Ludovico , Milic Natasa , Luzza Francesco , Boccuto Luigi , De Lorenzo Antonino 
Published: October 2017

Abstract
Nonalcoholic fatty liver disease (NAFLD) affects 25–30% of the general population worldwide and this high prevalence is linked with lifestyle and dietetic changes, not only in Western countries, but also in the urban areas of developing countries. Several pharmacological approaches were proposed in the treatment of NAFLD, but the reported results are inconclusive. International guidelines recommended the reduction of dietary fat and fructose, in association with some physical activity. In this context, it was reported that the protective effects of traditional Mediterranean diet, related to the high concentration of antioxidant compounds, particularly of polyphenols. Polyphenols are a heterogeneous class of plant derived compounds, with some proven hepatoprotective effects. Our opinion is that the adherence to traditional Mediterranean diet characterized by the consumption of antioxidant-rich foods in general and of polyphenols in particular, can be considered as a potential new approach in the treatment of NAFLD.
Cobalt ferrite nanoparticles (CoFe2O4 MNPs) as catalyst and support: magnetically recoverable nanocatalysts in organic synthesis
Authors: Kazemi Mosstafa , Ghobadi Massoud , Mirzaie Ali 
Published: October 2017

Abstract
Recovery and reusability of catalysts is an important aspect in modern catalysis research especially in organic synthesis. Compared to the conventional separation, magnetic separation has emerged as a robust, highly efficient, easy and rapid separation technique for products and catalysts. Cobalt ferrite nanoparticles are a well-known material, recognized as CoFe2O4 MNPs, and can be used as both catalyst and a versatile support for functionalization of metals, organocatalysts. In recent times, catalysis research has clearly experienced a renaissance in the area of utility of cobalt ferrite (CoFe2O4 MNPs) nanocatalysts based on their ability for recovery and reusability; the activity of these CoFe2O4 MNPs was investigated in a category of organic reactions. In this review, the fabrication, characterization, and application of cobalt ferrite (CoFe2O4 MNPs) nanocatalysts (CF-MNPs) in organic reactions have well summarized.
Preparation and characterization of collagen/chitosan/hyaluronic acid thin films for application in hair care cosmetics
Authors: Sionkowska Alina , Kaczmarek Beata , Michalska Marta , Lewandowska Katarzyna , Grabska Sylwia 
Published: October 2017

Abstract
In this study thin films based on a blend of collagen, chitosan and hyaluronic acids were prepared and their surface and mechanical properties were studied. The structure of the films was studied using FTIR spectroscopy, contact angle measurement and AFM images. Swelling and mechanical analyses were also performed. The hair protection possibility of collagen/chitosan/hyaluronic was studied using SEM microscopy and the mechanical testing of hair coated by the blends. It was found that the addition of hyaluronic acid to a collagen/chitosan blend improves the mechanical resistance of biopolymeric films. Samples with the addition of hyaluronic acid were more stable in aqueous conditions and provided higher roughness of surface.
The Use of Traditional Conservation Methods in the Preservation of Ancient Manuscripts: A Case Study from Indonesia
Authors: Rachman Yeni Budi 
Published: October 2017

Abstract:Indonesia has a rich heritage of manuscripts that represent the cumulative knowledge, values, experience, and practices of its people. This knowledge needs to be preserved. However, preservation does not need to use expensive equipment and materials. This paper examines some of the traditional methods and materials used to conserve manuscripts, and the philosophical viewpoints that underlie the traditional methods in Indonesia, based on a case study at Rekso Pustoko library at the Mangkunegaran Palace in Surakarta Province, Indonesia. This study used a qualitative approach with two research methods: a survey of manuscripts and one-on-one interviews with staff at Rekso Pustoko. The findings from the interviews indicated that traditional conservation methods are still applied by the caretakers of manuscripts. The use of vetiver and incense, of lemon grass, and the adjustment of air ventilation are the primary methods used in preservation. The findings also show that Javanese traditional philosophical understandings influence their conservation practices. The staffs believe that manuscripts are heirlooms from their ancestors, and if they disregard the ancestors, they will face hardships because of karma. The findings from this study are important in documenting empirical experiences in implementing traditional conservation methods to preserve the manuscripts’ intellectual content.
The Post-Truth Archive:Considerations for Archiving Context in Fake News Repositories
Authors: Commisso Corrie 
Published: October 2017

Abstract:Our current media environment is in a state of post-truth disruption: fake news is rampant, trusted media sources are viewed as partisan and suspect, and emotional appeal and personal belief hold more influence than objective facts. While many information professions are focused on combatting fake news through media literacy education, policy development, and advancements in search and social media technology, the archival profession has a slightly different task: evaluating how fake news can be preserved. The proliferation of fake news marks a significant cultural shift in information, politics, and identity, and is a valuable retrospective on how we consume and share media and assess its collective impact on society. But archiving fake news is a complex endeavor, particularly when it comes to ensuring that the archive includes enough context to help future researchers interpret the information. This article briefly explores some of the ways archivists may need to rethink traditional archival practices when developing repositories for fake news in their archives.