bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and management of intrathecal morphine-induced pruritus in New Zealand Māori healthcare recipients
Authors: Woods Jennifer M , Lim Anecita Gigi 
Published: July 2017

Aims and objectives: The aim of this article was to determine whether the incidence of intrathecal morphine-induced pruritus (ITMI) was influenced by ethnicity, age or gender in relation to orthopaedic versus caesarean surgeries. Background: The use of intrathecal morphine for patients undergoing total hip and knee joint replacements and for lower segment caesarean sections (LSCS) has gained popularity worldwide since its introduction over 30 years ago. Several international studies show that morphine delivered via the intrathecal route is an effective and safe method of pain relief. However, while the beneficial effects of intrathecal morphine have been clearly documented in many studies, so also have the adverse effects, predominantly being nausea and vomiting, pruritus and respiratory depression. Pruritus is described as one of the most common adverse effects, with a reported incidence of 30–100%. Design: A retrospective study was conducted using data collected over a 21-month period on post-operative patients who had received intrathecal morphine as their post-operative pain management. Methods: A two-phased approach was undertaken. The study was conducted to determine the incidence of ITMI pruritus among two patient groups, New Zealand Māori and New Zealand European, 96 subjects in total, and if treatment was received. Results: The findings revealed significant ethnic disparities whereas New Zealand Māori had a significantly higher rate of ITMI pruritus than New Zealand European, New Zealand Māori experienced the pruritus with more intensity and are less likely to be treated for it. Conclusion: Increased international knowledge and awareness for health professionals around the diversities of ethnicity and associated pharmacogenetics playing a significant role in patient response to opioid therapy can lead to improved overall care and patient satisfaction.
Concomitant multiple myeloma and probable phaeochromocytoma in a cat
Authors: Cervone Mario 
Published: July 2017

Case summary Herein a drug-resistant IgG-lambda-type multiple myeloma associated with probable phaeochromocytoma in a cat is described. A 12-year-old cat presented with weakness, weight loss, progressive blindness and open-mouth breathing, in addition to polyuria and polydipsia of 2 months’ duration. Abdominal ultrasonography revealed a left adrenal mass. Phaeochromocytoma was suspected on the basis of cytology and was associated with systemic hypertension. Biochemistry showed hyperproteinaemia. Serum protein electrophoresis revealed a narrow spike in the gamma region, identified as IgG lambda type at immunoelectrophoresis. Bone marrow cytology revealed an infiltrate with numerous mature plasma cells. The cat was resistant to two different drugs for multiple myeloma and was euthanased 6 months later because of anorexia and persistent poor general condition. Relevance and novel information This is the first clinical description of multiple myeloma associated with a suspected phaeochromocytoma in a cat.
Th17 immune microenvironment in Epstein-Barr virus–negative Hodgkin lymphoma: implications for immunotherapy
Authors: Duffield Amy S. , Ascierto Maria Libera , Anders Robert A. , Taube Janis M. , Meeker Alan K. , Chen Shuming , McMiller Tracee L. , Phillips Neil A. , Xu Haiying , Ogurtsova Aleksandra , Berger Alan E. , Pardoll Drew M. , Topalian Suzanne L. , Ambinder Richard F. 
Published: July 2017

Key Points
CHL broadly expresses the PD-1/PD-L1 pathway, but EBV+ CHL displays a Th1 profile, whereas EBV− tumors have a pathogenic Th17 profile. These findings support further studies to define the role of the IL-23/IL-17 axis in CHL response/resistance to anti-PD-1 therapy.
Building indeterminacy modelling – the ‘ZCB Bamboo Pavilion’ as a case study on nonstandard construction from natural materials
Authors: Crolla Kristof 
Published: July 2017

AbstractIf unprocessed natural materials are the most environmentally friendly construction materials available, how do we develop and communicate design model and construction information that allows dealing with their volatile indeterminacies?This paper discusses the design and development of the ‘ZCB Bamboo Pavilion’, a 30-metres-spanning, light-weight, bending-active gridshell from hand-tied bamboo poles, as a case study for the computational design and building information modelling of nonstandard architecture where both applied materials and employed craftsmanship are highly unpredictable in terms of accuracy and precision.Reflective practice and participatory action research are used to extract knowledge on and challenge the environment of practice, and improve design and construction strategies. The project is used to discuss how traditional construction can be augmented through the strategic injection of computation in the design and construction process, how computation allows for a different mode of collaboration with increased impact for the designer, and how bespoke building information models enable an expanded architectural design solution space.The paper concludes by arguing for a mode of digital design practice that more proactively operates within a field of real-world indeterminacy. The risk and ambiguity of working with indeterminacies are to be strategically balanced out against idealised digital set-ups and onsite opportunities.
Insights into Cedecea neteri strain M006 through complete genome sequence, a rare bacterium from aquatic environment
Authors: Chan Kok-Gan , Tan Wen-Si 
Published: July 2017

AbstractCedecea neteri M006 is a rare bacterium typically found as an environmental isolate from the tropical rainforest Sungai Tua waterfall (Gombak, Selangor, Malaysia). It is a Gram-reaction-negative, facultative anaerobic, bacillus. Here, we explore the features of Cedecea neteri M006, together with its genome sequence and annotation. The genome comprised 4,965,436 bp with 4447 protein-coding genes and 103 RNA genes.
Comparison of ISS, NISS, and RTS score as predictor of mortality in pediatric fall
Authors: Soni Kapil Dev , Mahindrakar Santosh , Gupta Amit , Kumar Subodh , Sagar Sushma , Jhakal Ashish 
Published: July 2017

AbstractBackgroundStudies to identify an ideal trauma score tool representing prediction of outcomes of the pediatric fall patient remains elusive. Our study was undertaken to identify better predictor of mortality in the pediatric fall patients.MethodsData was retrieved from prospectively maintained trauma registry project at level 1 trauma center developed as part of Multicentric Project—Towards Improving Trauma Care Outcomes (TITCO) in India. Single center data retrieved from a prospectively maintained trauma registry at a level 1 trauma center, New Delhi, for a period ranging from 1 October 2013 to 17 February 2015 was evaluated. Standard anatomic scores Injury Severity Score (ISS) and New Injury Severity Score (NISS) were compared with physiologic score Revised Trauma Score (RTS) using receiver operating curve (ROC).ResultsHeart rate and RTS had a statistical difference among the survivors to nonsurvivors. ISS, NISS, and RTS were having 50, 50, and 86% of area under the curve on ROCs, and RTS was statistically significant among them.ConclusionsPhysiologically based trauma score systems (RTS) are much better predictors of inhospital mortality in comparison to anatomical based scoring systems (ISS and NISS) for unintentional pediatric falls.
The mid-childhood and adolescent antecedents of women’s external locus of control orientation
Authors: Golding Jean , Gregory Steven , Iles-Caven Yasmin , Nowicki Stephen 
Published: July 2017

Background: External locus of control orientation (ELOC) is a powerful predictor of adverse consequences in regard to health, educational attainment, inter-personal relationships and well-being. Although many cross-sectional studies have been carried out, relatively little is known about antecedent factors influencing the development of ELOC. Methods: Over 12,000 pregnant women who enrolled in the Avon Longitudinal Study of Parents and Children (ALSPAC) in south-west England, had completed a brief version of the Adult Nowicki-Strickland Internal-External LOC scale, together with detailed questions concerning their own parents and childhood. A series of hypothesis-free structured backwards stepwise logistic regression analyses used an exposome approach with ELOC as the outcome. Results: Significant positive associations were found with smoking of the parents of the surveyed women, including prenatal exposure, and their own onset of regular smoking in mid-childhood (6-11 years). Increased odds of ELOC were also found with the absence of their fathers in early childhood, presence of older siblings, and with being born and brought up in the same area as they resided in at the time surveyed. Protective influences in the surveyed women included positive rating of their mother’s care, having a relatively educated mother, attending boarding school, their own age (the older they were, the less likely were they to have an external orientation), having a mentally ill parent, a sibling hospitalized or a relative die. Conclusions: There are two conclusions: (i) that not all stressful events contribute to the development of ELOC and it would be essential for models of antecedents of ELOC to take note of this complexity, and (ii) there are consistent (albeit unexpected) findings that highlight associations with cigarette smoke exposure of the woman from fetal life through to when starting to smoke regularly herself in mid-childhood. It is important that these findings are tested in other populations.
To Be or Not to Be Linked: Online Social Networks and Job Search by Unemployed Workforce
Authors: Garg Rajiv , Telang Rahul 
Published: July 2017

Prior research suggests that social connections, including acquaintances, friends, and family, are valuable in a job search process. In these studies, the size of an average job seeker’s network was much smaller and limited by the available modes of communication and the costs associated with maintaining social connections. However, the recent growth of online social networks has enabled job seekers to stay connected with many connections, weak or strong. Thus, the number of online connections—especially weak—has increased significantly. In this paper, we first examine whether an individual’s social network plays a role in driving job search behavior, taking into account online social networking sites (e.g., LinkedIn) and other job search modes. Second, we examine how ties in online social networks (both weak and strong) affect job search outcomes (modeled sequentially as job leads, interviews, and offers), and we compare the findings to job outcomes from traditional job search modes (e.g., career fairs, newspaper, Internet postings, and friends and family). To do so, we first construct an economic model of search behavior incorporating cost and benefit functions; we then estimate the model to recover structural parameters using the survey data of 424 users. Our findings show that users are spending more time searching for jobs on social networking sites. In addition, users’ strong ties play a significant role in job search and are especially helpful in generating job leads, interviews, and offers; the weak ties, on average, are ineffective in generating positive outcomes and marginally negative in some cases. This paper was accepted by Lorin Hitt, information systems.
Competing by Restricting Choice: The Case of Matching Platforms
Authors: Halaburda Hanna , Jan Piskorski Mikołaj , Yıldırım Pınar 
Published: July 2017

We show that a two-sided matching platform can successfully compete by limiting the number of choices it offers to its customers, while charging higher prices than platforms with unrestricted choice. We develop a stylized model of online dating where agents with different outside options match based on how much they like each other. Starting from these microfoundations, we derive the strength and direction of indirect network effects and show that increasing the number of potential matches has a positive effect due to larger choice, but also a negative effect due to competition between agents on the same side. Agents resolve the trade-off between these competing effects differently, depending on their outside options. For agents with high outside options, the choice effect is stronger than the competition effect, leading them to prefer an unrestricted-choice platform. The opposite is the case for agents with low outside options, who then have higher willingness to pay for a platform restricting choice, as it also restricts the choice set of their potential matches. Moreover, since only agents with low outside options self-select into the restricted choice platform, the competition effect is mitigated further. This allows multiple platforms offering different number of choices to coexist without the market tipping. This paper was accepted by Bruno Cassiman, business strategy.
Stochastic Dynamic Inventory Problem Under Explicit Inbound Transportation Cost and Capacity
Authors: Zhang Liqing , Çetinkaya Sıla 
Published: July 2017

We study a practical generalization of the classical stochastic dynamic inventory problem where privately owned trucks with limited cargo capacity are used to transport the replenishment quantity. The resulting replenishment cost function also includes the traditional fixed setup cost, and it is known as a multiple setup cost structure, which leads to complicated cost-to-go functions in the problem of interest. We introduce the concepts of non-(Δ, C)-decreasing and [Formula: see text], and we develop a sophisticated replenishment policy called the [Formula: see text] policy. We examine the sufficient conditions under which the new policy is optimal. Our results offer a detailed characterization of optimal policies and generalize the existing theory on the concepts of K-convexity and non-K-decreasing. In doing so, we are able to investigate a traditional stochastic inventory problem which has remained open in the literature for more than four decades. The online appendix is available at https://doi.org/10.1287/opre.2017.1625 .
On the impossibility of archiving the radio and its virtues
Authors: Hagen Wolfgang 
Published: July 2017

Abstract
The article discusses the general history of the radio archive in Germany. Such archives were established since radio broadcasts were pre-produced. Firstly, this was the case in 1928 and led to the set-up of appropriate departments, deliberated to deliver the pre-recorded sound carriers right on time for the transmission. This is the beginning of the radio archive, which therefore at no time followed an archival idea. For this reason, even today, there are no radio archives that meet archival principles. In this respect, we propose to make the contents of the ­existing – so-called – radio archives available on the World Wide Web according to the model of UbuWeb that by now holds successful important artistic audio-visual documents for two decades.
Lossless compression and the future of memory
Authors: Jancovic Marek 
Published: July 2017

Abstract
Lossless video compression codecs such as FFV1 are currently emerging as a central organizing principle of archival practice. With reference to the perceived perfect reproducibility of digital objects, they promise to alleviate one of the great burdens of media preservation: decay. Recent large-scale international efforts to standardize lossless archival storage signalize a profound change in the relationship between loss, memory and history. This article examines the volatile status of lossless compression within cultural heritage institutions working towards format standardization. Engaging with a broader critique of contemporary archival policies, it questions the certainty with which lossless compression schemes frame decay as loss and contributes to the discussion surrounding the historicity and materiality of digitized objects and the historical value of decay for cultural heritage.
Searching for D-9.com in the archives: An archaeology of a film’s website
Authors: Walden Kim Louise 
Published: July 2017

Abstract
Film marketing materials such as trailers and posters are regarded as ephemeral, but as they have migrated online, they have become increasingly pervasive and intriguing forms, colonizing the spaces before, between and beyond the film itself. The distinctions between promotion and content have become blurred, and arguably, some marketing campaigns have become as entertaining as the films they promote, which raises questions about the cultural value of these ephemera. In setting out to investigate what film websites contribute to the narrative ecology of the film, the award-winning promotional website for Neill Blomkamp’s District 9 (2009) promised to be a good starting point. However, the research did not get off to an auspicious start because shortly after it began, the site disappeared. The article gives an account of a media archaeological excavation undertaken to search for D-9.com. A search led to encounters with a wide range of digital archives including the Internet Archive and its Wayback Machine, the Webby awards as well the ‘new’ generation of Web 2.0 archives such as blogs, YouTube and social media sites. In the light of this journey, the article will reflect on digital archives from what media theorist Wolfgang Ernst referred to as the ‘machine perspective’ and how the mechanisms of the digital archives condition the way we know things about the recent digital past. It will conclude by suggesting that these archival encounters in this project revealed as much about the nature of digital archives as online film marketing and promotion.
The materials of memory: Tracing archives in communication studies
Authors: Timcke Scott 
Published: July 2017

Abstract
This article contributes notes towards the development of a communicative approach to investigating archives. Such an approach is vital if one wishes to review features ranging from political or cultural reference points to the ecology of communication in the modern state. Through splicing together recent developments in the philosophy of mind with scientific publications on the bio-chemical cognitive process of memory, a case is presented where the archive is a useful bedrock concept when considering communication processes. A latent goal turns on the hope of sparking a renewed appreciation of archival systems and their place within the wider body of communication theory.
A model of non-player character believability
Authors: Warpefelt Henrik , Verhagen Harko 
Published: July 2017

Abstract
In this study we aim to describe in what ways the behaviour of non-player characters (NPCs) affects to what extent the player finds the game experience to be believable. To this end, we have conducted an online survey, where respondents were asked to classify and describe NPCs. Furthermore, we also examined recordings of NPCs in games. These data sources were analysed using a model for NPC social believability in order to describe the effects of NPC behaviour in relation to how different types of NPCs are perceived as being believable. Based on this we were able to construct a model of NPC believability, which describes the NPC’s level of complexity and ability to handle a mutable social context. As described by the model, NPCs are currently less capable of handling changing social contexts. They do, however, show promise, and given current emerging technologies it is feasible that new types of more socially capable NPCs will arise within the near future.
Digital games and moral packaging: The impacts of in-game decisions on public pedagogical deliberation
Authors: Malazita James W. , Jenkins Alexander 
Published: July 2017

Abstract
This article examines the impact of the use of moral game designs in mainstream games upon public discourse. Rather than interviewing players about their moral experiences after gameplay, this article reads moral engagement through the pedagogical lens of Freire: that moral engagement must be measured through pedagogical action in the public sphere. Through discourse analysis, this article examines the presence and quality of moral deliberation and pedagogical action in online message boards surrounding three morally charged games: Mass Effect 3, Modern Warfare 2 and Civilization V. In the cases examined, players rarely adopted the ‘moral point of view’ or engaged in public pedagogy, opting instead to frame moral scenarios as ‘play’. A notable exception occurs when the content of the moral scenarios has already been explicitly framed in the public sphere as a matter for public moral debate.
Figure and ground, image and sound: The digital medium in Brian Eno’s Thursday Afternoon
Authors: Leung Godfre 
Published: July 2017

Abstract
This article analyses the discrepancy between the medium-specificity of Brian Eno’s 1985 compact disc (CD) Thursday Afternoon and the intermediality of its precursor, Eno’s 1984 video artwork of the same name. I historicize these seemingly contrasting aesthetic strategies vis-à-vis medium alongside an epistemological shift in our conception of the musical recording during the rise of the CD in the early-to-mid-1980s. I argue the counter-intuitive point that the home video version of Thursday Afternoon represents the fullest realization of Eno’s medium-specific inquiry into the emergent CD technology.
Existence results for Schrödinger–Choquard–Kirchhoff equations involving the fractional p-Laplacian
Authors: Pucci Patrizia , Xiang Mingqi , Zhang Binlin 
Published: July 2017

Abstract
The paper is concerned with existence of nonnegative solutions
of a Schrödinger–Choquard–Kirchhoff-type fractional p-equation. As a consequence,
the results can be applied to the special case

(

a
+

b
⁢

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p
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θ
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Δ

)

p
s

⁢
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+

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=

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f
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,
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)

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,
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,

(a+b\|u\|_{s}^{p(\theta-1)})[(-\Delta)^{s}_{p}u+V(x)|u|^{p-2}u]=\lambda f(x,u)%
+\Bigg{(}\int_{\mathbb{R}^{N}}\frac{|u|^{p_{\mu,s}^{*}}}{|x-y|^{\mu}}\,dy%
\Biggr{)}|u|^{p_{\mu,s}^{*}-2}u\quad\text{in }\mathbb{R}^{N},

where

∥
u
∥

s

=

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)

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,

\|u\|_{s}=\Bigg{(}\iint_{\mathbb{R}^{2N}}\frac{|u(x)-u(y)|^{p}}{|x-y|^{N+ps}}%
\,dx\,dy+\int_{\mathbb{R}^{N}}V(x)|u|^{p}\,dx\Biggr{)}^{\frac{1}{p}},

a
,
b

∈

ℝ
0
+

{a,b\in\mathbb{R}^{+}_{0}}

, with

a
+
b

>
0

{a+b>0}

,

λ
>
0

{\lambda>0}

is a parameter,

s
∈

(
0
,
1
)

{s\in(0,1)}

,

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>

p
⁢
s

{N>ps}

,

θ
∈

[
1
,

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/

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-

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s

)

)

{\theta\in[1,N/(N-ps))}

,

(

-
Δ

)

p
s

{(-\Delta)^{s}_{p}}

is the fractional p-Laplacian,

V
:

ℝ
N

→

ℝ
+

{V:\mathbb{R}^{N}\rightarrow\mathbb{R}^{+}}

is a potential function,

0
<
μ
<
N

{0<\mu<N}

,

p

μ
,
s

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=

(

p
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N

-

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/
2

)

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(

N
-

p
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)

{p_{\mu,s}^{*}=(pN-p\mu/2)/(N-ps)}

is the critical exponent in the sense of Hardy–Littlewood–Sobolev inequality, and

f
:

ℝ
N

×
ℝ

→
ℝ

{f:\mathbb{R}^{N}\times\mathbb{R}\rightarrow\mathbb{R}}

is a Carathéodory function.
First, via the Mountain Pass theorem, existence of nonnegative solutions
is obtained when f satisfies superlinear growth conditions and λ
is large enough. Then, via the Ekeland variational principle, existence of
nonnegative solutions is investigated when f is sublinear at infinity and λ is small enough. More intriguingly, the paper covers a novel feature of Kirchhoff problems, which is the fact that the parameter a can be zero. Hence the results of the paper are new even for the standard stationary Kirchhoff problems.