bluuebunny/crossref_metadata_2025_split huggingface dataset:
Timing of Locomotor Recovery from Anoxia Modulated by the white Gene in Drosophila
Authors: Xiao Chengfeng , Robertson R Meldrum 
Published: March 2016

Abstract
Locomotor recovery from anoxia follows the restoration of disordered ion distributions and neuronal excitability. The time taken for locomotor recovery after 30 sec anoxia (around 10 min) is longer than the time for the propagation of action potentials to be restored (&lt;1 min) in Drosophila wild type. We report here that the white (w) gene modulates the timing of locomotor recovery. Wild-type flies displayed fast and consistent recovery of locomotion from anoxia, whereas mutants of w showed significantly delayed and more variable recovery. Genetic analysis including serial backcrossing revealed a strong association between the w locus and the timing of locomotor recovery, and haplo-insufficient function of w+ in promoting fast recovery. The locomotor recovery phenotype was independent of classic eye pigmentation, although both are associated with the w gene. Introducing up to four copies of mini-white (mw+) into w1118 was insufficient to promote fast and consistent locomotor recovery. However, flies carrying w+ duplicated to the Y chromosome showed wild-type-like fast locomotor recovery. Furthermore, Knockdown of w by RNA interference (RNAi) in neurons but not glia delayed locomotor recovery, and specifically, knockdown of w in subsets of serotonin neurons was sufficient to delay the locomotor recovery. These data reveal an additional role for w in modulating the timing of locomotor recovery from anoxia.
Universalidade do Direito à Saúde
Authors: Madureira Amanda Silva , Sena Jaqueline Prazeres 
Published: March 2016

O que compõe a universalidade do direito à saúde? Quais são os seus desafios diante das crescentes necessidades dos indivíduos em uma sociedade cuja concepção liberal e de escassez de recursos pode reduzir a prestação dos serviços de saúde? Essas e outras questões servem de esteio na análise acurada da autora Edith Maria Barbosa Ramos. A obra, fruto de sua tese de doutoramento junto ao Programa de Pós-Graduação em Políticas Públicas da Universidade Federal do Maranhão, traça importante percurso histórico nos textos e declarações jurídicos que proporcionaram ao direito à saúde a categoria de direito humano fundamental.
RAMOS, Edith Maria Barbosa. Universalidade do Direito à Saúde. São Luís: EDUFMA, 2014.
Capital social estructural y educación, un estudio desde la perspectiva de Pierre Bourdieu: Estudio de caso Universidad ECCI
Authors: Cabrera Jiménez Manuel Fernando , Infante Rincón Claudia Liliana 
Published: March 2016

<p>Este estudio ha sido desarrollado con el fin de identificar el nivel de capital social estructural en el contexto educativo de la Universidad ECCI. El trabajo se desarrolló con base en el planteamiento de una hipótesis una revisión teórica centrando su atención en los postulados de Pierre Bourdieu y otros referentes teóricos destacados en el tema. Se utilizó una metodología de corte descriptiva con un enfoque cuantitativo con dos variables: estudiantes matriculados a partir de tercer semestre y docentes de planta, vinculados a la institución desde el año 2013. Se diseñó un instrumento para la recolección de la información, compuesto por tres dimensiones, el capital social cognitivo, el capital social estructural y la inclusión. El objetivo de este artículo es dar cuenta de los resultados obtenidos en la dimensión estructural del capital social caracterizada por el perfeccionamiento de relaciones normalizadas que potencialicen estrategias orientadas a fortalecer la asociatividad. La investigación permitió concluir que los niveles de capital social estructural en la Universidad ECCI presentan una tendencia media baja, lo cual se puede considerar como una deficiencia para la construcción de capital social, situación que demanda un plan estratégico que potencialice y se asuma como objetivo colectivo para el bienestar.</p>
A Unified Model for Gas Transfer in Nanopores of Shale-Gas Reservoirs: Coupling Pore Diffusion and Surface Diffusion
Authors: Wu Keliu , Li Xiangfang , Guo Chaohua , Wang Chenchen , Chen Zhangxin 
Published: March 2016

SummaryA model for gas transfer in nanopores is the basis for accurate numerical simulation, which has important implications for economic development of shale-gas reservoirs (SGRs). The gas-transfer mechanism in SGRs is significantly different from that of conventional gas reservoirs, which is mainly caused by the nanoscale phenomena and organic matter as a medium of gas sourcing and storage. The gas-transfer mechanism includes bulk-gas transfer and adsorption-gas surface diffusion in nanopores of SGRs, where the bulk-gas-transfer mechanism includes continuous flow, slip flow, and Knudsen diffusion. First, a model for bulk-gas transfer in nanopores was established, which was dependent on slip flow and Knudsen diffusion. The total gas flux in the bulk phase is not a simple sum of slip-flow flux and Knudsen-diffusion flux but a weighted sum on the basis of corresponding contributions. The weighted factors are primarily controlled by the mutual interaction between slip flow and Knudsen diffusion, which is determined by probabilities between gas molecules colliding with each other and colliding with nanopore surface in this newly proposed model. Second, a model for adsorbed-gas surface diffusion in nanopores was established, which was modeled after the Hwang and Kammermeyer (1966) model and considered the effect of gas coverage under a high-pressure condition. Finally, with the combination of these two models, a unified model for gas transport in nanopores of SGRs was established, and this model was validated through molecular simulation and experimental data. Results show that:Slip flow makes a great contribution to gas transfer under the condition of meso/macropores (pore radius greater than 2 nm) and high pressure. Knudsen diffusion makes an important contribution to gas transfer under the condition of macropores (pore radius greater than 50 nm) and less than 1 MPa in pressure, whereas it can be ignored in other cases. A surface-diffusion coefficient is comparable with a pore-diffusion coefficient, and gas transfer is always dominated by surface diffusion over all the ranges of pressure in micropores (pore radius ≤ 2 nm). Surface-diffusion contribution decreases with an increase in pore size, isosteric sorption heat, pressure, and temperature in SGRs.
Characterization of leptospirosis among dogs in Oregon, 2007–2011
Authors: Grayzel Sharon E. , DeBess Emilio E. 
Published: March 2016

Abstract
OBJECTIVE To characterize the demographics, exposure risks, and outcomes for dogs with leptospirosis in Oregon between 2007 and 2011 and to identify geographic and temporal distributions of known cases of canine leptospirosis within the state during this period.
DESIGN Retrospective descriptive epidemiological study.
ANIMALS 72 dogs.
PROCEDURES Reports of laboratory tests for leptospirosis and zoonosis reporting forms voluntarily submitted by veterinarians to the Oregon Health Authority were evaluated to identify dogs with leptospirosis during the study period; data were also collected by examination of medical records or by telephone surveys with veterinarians from reporting facilities.
RESULTS 72 confirmed cases of leptospirosis were identified; surveys were completed for 65 cases. Seasonal and spatial distributions coincided with rainfall patterns for the state, with most cases diagnosed in the spring and in the western part of the state. Common exposure risks included contact with water in the environment (14/65) and contact with wildlife (14); 33 dogs had no history of known exposure risks. Among dogs with other conditions at the time of diagnosis (26/64), dermatitis, otitis, or both were the most commonly reported findings (9/26). Of 65 dogs, 44 recovered, 12 died or were euthanized because of leptospirosis, and 9 were lost to follow-up.
CONCLUSIONS AND CLINICAL RELEVANCE Distribution of canine leptospirosis cases in Oregon fit the rainfall theory pattern. Dermatologic conditions were present in 9 of 64 (14%) dogs that had a diagnosis of leptospirosis; however, further investigation is needed to determine whether such conditions predispose dogs to the disease.
The Microtubule-Associated Protein Lis1 Regulates T Lymphocyte Homeostasis and Differentiation
Authors: Ngoi Soo M. , Lopez Justine M. , Chang John T. 
Published: March 2016

Abstract
The microtubule-associated protein lissencephaly 1 (Lis1) is a key regulator of cell division during stem cell renewal and differentiation. In this study, we examined the role of Lis1 in T lymphocyte homeostasis and fate diversification in response to microbial infection. T cell–specific deletion of Lis1 resulted in depletion of the peripheral CD4+ and CD8+ T lymphocyte pool owing to a loss of homeostatic, cytokine-induced proliferation. In contrast, cognate Ag-triggered proliferation was much less affected, enabling Lis1-deficient CD8+ T cells to differentiate into terminal effector cells in response to microbial infection. Strikingly, however, the specification of Lis1-deficient long-lived memory CD8+ T lymphocytes was impaired due, in part, to an apparent failure to differentiate appropriately to IL-15. Taken together, these findings suggest that Lis1 plays an important role in T cell homeostasis and the generation of memory T lymphocytes.
Optimization of an enclosed gas analyzer sampling system for measuring eddy covariance fluxes of H2O and CO2
Authors: Metzger Stefan , Burba George , Burns Sean P. , Blanken Peter D. , Li Jiahong , Luo Hongyan , Zulueta Rommel C. 
Published: March 2016

Abstract. Several initiatives are currently emerging to observe the exchange of energy and matter between the earth's surface and atmosphere standardized over larger space and time domains. For example, the National Ecological Observatory Network (NEON) and the Integrated Carbon Observing System (ICOS) are set to provide the ability of unbiased ecological inference across ecoclimatic zones and decades by deploying highly scalable and robust instruments and data processing. In the construction of these observatories, enclosed infrared gas analyzers are widely employed for eddy covariance applications. While these sensors represent a substantial improvement compared to their open- and closed-path predecessors, remaining high-frequency attenuation varies with site properties and gas sampling systems, and requires correction. Here, we show that components of the gas sampling system can substantially contribute to such high-frequency attenuation, but their effects can be significantly reduced by careful system design. From laboratory tests we determine the frequency at which signal attenuation reaches 50 % for individual parts of the gas sampling system. For different models of rain caps and particulate filters, this frequency falls into ranges of 2.5–16.5 Hz for CO2, 2.4–14.3 Hz for H2O, and 8.3–21.8 Hz for CO2, 1.4–19.9 Hz for H2O, respectively. A short and thin stainless steel intake tube was found to not limit frequency response, with 50 % attenuation occurring at frequencies well above 10 Hz for both H2O and CO2. From field tests we found that heating the intake tube and particulate filter continuously with 4 W was effective, and reduced the occurrence of problematic relative humidity levels (RH  > 60 %) by 50 % in the infrared gas analyzer cell. No further improvement of H2O frequency response was found for heating in excess of 4 W. These laboratory and field tests were reconciled using resistor–capacitor theory, and NEON's final gas sampling system was developed on this basis. The design consists of the stainless steel intake tube, a pleated mesh particulate filter and a low-volume rain cap in combination with 4 W of heating and insulation. In comparison to the original design, this reduced the high-frequency attenuation for H2O by  ≈ 3∕4, and the remaining cospectral correction did not exceed 3 %, even at high relative humidity (95 %). The standardized design can be used across a wide range of ecoclimates and site layouts, and maximizes practicability due to minimal flow resistance and maintenance needs. Furthermore, due to minimal high-frequency spectral loss, it supports the routine application of adaptive correction procedures, and enables largely automated data processing across sites.
Earth System Chemistry integrated Modelling (ESCiMo) with the Modular Earth Submodel System (MESSy) version 2.51
Authors: Jöckel Patrick , Tost Holger , Pozzer Andrea , Kunze Markus , Kirner Oliver , Brenninkmeijer Carl A. M. , Brinkop Sabine , Cai Duy S. , Dyroff Christoph , Eckstein Johannes , Frank Franziska , Garny Hella , Gottschaldt Klaus-Dirk , Graf Phoebe , Grewe Volker , Kerkweg Astrid , Kern Bastian , Matthes Sigrun , Mertens Mariano , Meul Stefanie , Neumaier Marco , Nützel Matthias , Oberländer-Hayn Sophie , Ruhnke Roland , Runde Theresa , Sander Rolf , Scharffe Dieter , Zahn Andreas 
Published: March 2016

Abstract. Three types of reference simulations, as recommended by the Chemistry–Climate Model Initiative (CCMI), have been performed with version 2.51 of the European Centre for Medium-Range Weather Forecasts – Hamburg (ECHAM)/Modular Earth Submodel System (MESSy) Atmospheric Chemistry (EMAC) model: hindcast simulations (1950–2011), hindcast simulations with specified dynamics (1979–2013), i.e. nudged towards ERA-Interim reanalysis data, and combined hindcast and projection simulations (1950–2100). The manuscript summarizes the updates of the model system and details the different model set-ups used, including the on-line calculated diagnostics. Simulations have been performed with two different nudging set-ups, with and without interactive tropospheric aerosol, and with and without a coupled ocean model. Two different vertical resolutions have been applied. The on-line calculated sources and sinks of reactive species are quantified and a first evaluation of the simulation results from a global perspective is provided as a quality check of the data. The focus is on the intercomparison of the different model set-ups. The simulation data will become publicly available via CCMI and the Climate and Environmental Retrieval and Archive (CERA) database of the German Climate Computing Centre (DKRZ). This manuscript is intended to serve as an extensive reference for further analyses of the Earth System Chemistry integrated Modelling (ESCiMo) simulations.
Here, There and Everywhere: Glocalising Identities in Transworld Transmedia Genius Loci
Authors: Coppock Patrick John 
Published: March 2016

The principle question discussed in this essay is essentially a philosophical or existential one: in our increasingly remediated, interconnected, physically and virtually mobile contemporary world, is it is conceivable, or feasible, for us actually to be “here, there, and everywhere” at one and the same time?
Have our predominantly “local” personal, professional and collective narrative histories, and the various cultural traditions that have grown out of these, really furnished us with relational identity skills that enable us to participate positively and actively in ongoing globalisation processes and to play a constructive, active, ethical role in the global gameplay arena?
Or do we need to work more with non-familiar forms of otherness if we want to develop new types of “glocal” identities, able to mediate and transcend the emotional, conceptual, cultural and other divides that may hinder the identification, management and just balancing of “global” and “local” needs, rights and interests?
As a contribution to further interdisciplinary debate on this and related themes, in media studies and elsewhere, this essay intentionally seeks to provoke*, by offering some engaged, informed but clearly speculative considerations, regarding the valorisation, application and evaluation of new digital media designed to facilitate ludic transworld, transmedia cooperition at-a-distance, to develop practical strategies to engage in responsible, ethical, ecological, mutually sustainable ways, with non-copresent, non-local others and their own past, present and future actual, and possible, worlds.

*“Provoke”, of course, is not meant here in any “mean” or negative way, but rather as a ludic challenge to my readers to experiment in engaging with ‘non-local’, ‘non-standard’ forms of otherness – which in the case of this essay is the actual diversity of forms, norms and practices in academic writing. This First Page Footnote also seems an appropriate place to offer my sincere thanks to two anonymous reviewers of a first draft version of this essay, both of whom, each with their own brand of provocative, stimulating and useful remarks, are hereforth anointed as contributing co-authors, of this its (hopefully) final version.
Auto-correlation of journal impact factor for consensus research reporting statements: a cohort study
Authors: Shanahan Daniel R. 
Published: March 2016

Background.The Journal Citation Reports journal impact factors (JIFs) are widely used to rank and evaluate journals, standing as a proxy for the relative importance of a journal within its field. However, numerous criticisms have been made of use of a JIF to evaluate importance. This problem is exacerbated when the use of JIFs is extended to evaluate not only the journals, but the papers therein. The purpose of this study was therefore to investigate the relationship between the number of citations and journal IF for identical articles published simultaneously in multiple journals.Methods.Eligible articles were consensus research reporting statements listed on the EQUATOR Network website that were published simultaneously in three or more journals. The correlation between the citation count for each article and the median journal JIF over the published period, and between the citation count and number of article accesses was calculated for each reporting statement.Results.Nine research reporting statements were included in this analysis, representing 85 articles published across 58 journals in biomedicine. The number of citations was strongly correlated to the JIF for six of the nine reporting guidelines, with moderate correlation shown for the remaining three guidelines (medianr= 0.66, 95% CI [0.45–0.90]). There was also a strong positive correlation between the number of citations and the number of article accesses (medianr= 0.71, 95% CI [0.5–0.8]), although the number of data points for this analysis were limited. When adjusted for the individual reporting guidelines, each logarithm unit of JIF predicted a median increase of 0.8 logarithm units of citation counts (95% CI [−0.4–5.2]), and each logarithm unit of article accesses predicted a median increase of 0.1 logarithm units of citation counts (95% CI [−0.9–1.4]). This model explained 26% of the variance in citations (median adjustedr2= 0.26, range 0.18–1.0).Conclusion.The impact factor of the journal in which a reporting statement was published was shown to influence the number of citations that statement will gather over time. Similarly, the number of article accesses also influenced the number of citations, although to a lesser extent than the impact factor. This demonstrates that citation counts are not purely a reflection of scientific merit and the impact factor is, in fact, auto-correlated.
Mineral dust transport toward Hurricane Helene (2006)
Authors: Schwendike Juliane , Jones Sarah C. , Vogel Bernhard , Vogel Heike 
Published: March 2016

AbstractThis study investigates the transport of mineral dust from its source regions in West Africa toward the developing tropical cyclone Helene (2006) and diagnoses the resulting properties of the air influencing the tropical cyclonegenesis. The model system COSMO‐ART (Consortium for Small‐Scale Modelling‐Aerosols and Reactive Trace gases) in which the emission and transport of mineral dust as well as the radiation feedback are taken into account, was used. The emission of mineral dust between 9 and 14 September 2006 occurred in association with the relatively strong monsoon flow and northeasterly trade winds, with gust fronts of convective systems over land, and with the Atlantic inflow. Additionally, increased surface wind speed was linked to orographical effects at the Algerian Mountains, Atlas Mountains, and the Hoggar. The dust, as part of the Saharan air layer, is transported at low levels by the monsoon flow, the Harmattan, the northeasterly trade winds, and the monsoon trough, and is transported upward in the convergence zone between Harmattan and monsoon flow, in the baroclinic zone along the West African coastline, and by convection. At around 700 hPa the dust is transported by the African easterly jet. Dry and dust‐free air is found to the north‐northwest of the developing tropical depression due to descent in an anticyclone. Based on the model data, it was possible to distinguish between dry (from the anticyclone), dry and dusty (from the Harmattan and northeasterly trade winds), and dusty and moist air (from the monsoon flow and in the tropical depression due to convection).
Optimization of injection location based on simulations of CO2 leakage through multiple leakage pathways
Authors: Yu Bo , Wang Le , Liu Yongzhong 
Published: March 2016

AbstractAn optimization methodology is proposed to determine an appropriate injection location among potential candidates. The method identifies the optimal injection location by minimizing the total CO2 leakage from all leakage pathways present at a given site. The case of a single injection well and a single leakage pathway is used to quantify the relationships between CO2 leakage rate and major factors. A mathematical model is numerically solved and used to establish a correlation for each factor. The results are extended to the situation of a single injection well and multiple leakage pathways. An explicit expression correlating the asymptotic CO2 leakage rate to the major factors is proposed. Four case studies are illustrated. The results show that the optimal injection location is different in each case and is significantly influenced by the three factors. The proposed approach provides a quantitative tool for minimizing CO2 leakage risk at sites with multiple leakage pathways. © 2016 Curtin University of Technology and John Wiley & Sons, Ltd.
Investigation of the behavior of hydrogen‐bonded phenolic compounds and their determination by using poly(vinylferrocenium)–polyaniline composite film
Authors: Kavanoz Muammer , Pekmez Nuran Özçiçek , Can Muzaffer 
Published: March 2016

ABSTRACTThe hydrogen bonding between phenolic compounds (phenol (Ph), catechol (Ct), resorcinol (Rs), and hydroquinone (Hq)) is investigated at pH 4. The oxidation behaviors of total phenolic compounds (TotPh) are different from their individual behaviors due to the existence of intermolecular hydrogen‐bonded oligomeric clusters. Theoretical calculations and voltammetric and spectroscopic evidences support the intermolecular hydrogen bonding. The interaction of the phenolic compounds with polyaniline (PANI) and poly(vinylferrocenium) (PVF+) films are also investigated electrochemically and spectroscopically. The phenolic molecules are immobilized in both polymers due to the construction of hydrogen bonds by PANI and the complexation with PVF+. In addition, Ct and Hq are catalytically oxidized by PANI. Determinations of Ct and TotPh are performed on PVF+–PANI composite‐coated Pt electrode using amperometric I–t method. Composite coating exhibits significant electrochemical activity toward Ct and TotPh, with high sensitivity and a wide linearity range. The steady‐state currents versus concentration of Ct and TotPh are found to be linear in the range of 1.35 × 10−3−50.0 mM and 4.10 × 10−4−560 mM for two linear regions, respectively. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43596.