bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facile Fabrication of Hierarchically Thermoresponsive Binary Polymer Pattern for Controlled Cell Adhesion
Authors: Hou Jianwen , Cui Lele , Chen Runhai , Xu Xiaodong , Chen Jiayue , Yin Ligang , Liu Jingchuan , Shi Qiang , Yin Jinghua 
Published: January 2018

AbstractA versatile platform allowing capture and detection of normal and dysfunctional cells on the same patterned surface is important for accessing the cellular mechanism, developing diagnostic assays, and implementing therapy. Here, an original and effective method for fabricating binary polymer brushes pattern is developed for controlled cell adhesion. The binary polymer brushes pattern, composed of poly(N‐isopropylacrylamide) (PNIPAAm) and poly[poly(ethylene glycol) methyl ether methacrylate] (POEGMA) chains, is simply obtained via a combination of surface‐initiated photopolymerization and surface‐activated free radical polymerization. This method is unique in that it does not utilize any protecting groups or procedures of backfilling with immobilized initiator. It is demonstrated that the precise and well‐defined binary polymer patterns with high resolution are fabricated using this facile method. PNIPAAm chains capture and release cells by thermoresponsiveness, while POEGMA chains possess high capability to capture dysfunctional cells specifically, inducing a switch of normal red blood cells (RBCs) arrays to hemolytic RBCs arrays on the pattern with temperature. This novel platform composed of binary polymer brush pattern is smart and versatile, which opens up pathways to potential applications as microsensors, biochips, and bioassays.
Recyclable Cu(II)‐Coordination Crosslinked Poly(benzimidazolyl pyridine)s as High‐Performance Polymers
Authors: Wang Cheng , Yang Li , Chang Guanjun 
Published: January 2018

AbstractCrosslinked high‐performance polymers have many industrial applications, but are difficult to recycle or rework. A novel class of recyclable crosslinking Cu(II)‐metallo‐supramolecular coordination polymers are successfully prepared, which possess outstanding thermal stability and mechanical property. More importantly, the Cu2+ coordination interactions can be further removed via external pyrophosphate to recover the linear polymers, which endow the crosslinking polymers with recyclability.
Unilateral winged scapula: Clinical and electrodiagnostic experience with 128 cases, with special attention to long thoracic nerve palsy
Authors: Seror Paul , Lenglet Timothee , Nguyen Christelle , Ouaknine MichaëL , Lefevre‐Colau Marie Martine 
Published: January 2018

ABSTRACTIntroduction: In this study we report a large series of patients with unilateral winged scapula (WS), with special attention to long thoracic nerve (LTN) palsy. Methods: Clinical and electrodiagnostic data were collected from 128 patients over a 25‐year period. Results: Causes of unilateral WS were LTN palsy (n = 70), spinal accessory nerve (SAN) palsy (n = 39), both LTN and SAN palsy (n = 5), facioscapulohumeral dystrophy (FSH) (n = 5), orthopedic causes (n = 11), voluntary WS (n = 6), and no definite cause (n = 2). LTN palsy was related to neuralgic amyotrophy (NA) in 61 patients and involved the right side in 62 patients. Discussion: Clinical data allow for identifying 2 main clinical patterns for LTN and SAN palsy. Electrodiagnostic examination should consider bilateral nerve conduction studies of the LTN and SAN, and needle electromyography of their target muscles. LTN palsy is the most frequent cause of unilateral WS and is usually related to NA. Voluntary WS and FSH must be considered in young patients. Muscle Nerve 57: 913–920, 2018
Performance analysis of the cultural and creative industry: a network‐based approach
Authors: Lu Wen‐Min , Kweh Qian Long , He Dong‐Sing , Shih Jui‐Min 
Published: January 2018

AbstractThe cultural and creative industries (CCIs) in Taiwan have gradually contributed to the national economy under the impetus of government policies. We employ a two‐stage data envelopment analysis model with an additive efficiency decomposition approach to measure the profitability and marketability of 22 Taiwanese cultural and creative companies. Furthermore, we employ the network‐based ranking approach to identify benchmark inputs/outputs, and the strengths and weakness of each company. Our empirical results show that the profitability of the cultural and creative companies is better than their marketability. Companies in the industries of publishing, creative life, popular music, and cultural content averagely perform better than those in the other three types of CCIs in terms of profitability. Companies in the creative life industry are on average more efficient than those in the other five types of CCIs in terms of marketability. The profitability/marketability matrix of cultural and creative companies is also presented.
Application of improved chicken swarm optimization for MPPT in photovoltaic system
Authors: Wu Zhongqiang , Yu Danqi , Kang Xiaohua 
Published: January 2018

SummaryThe chicken swarm optimization algorithm is a new biology optimization algorithm, but its high‐dimensional operation usually causes deviation and the iteration time of optimizing is a little long. An improved chicken swarm optimization algorithm is proposed. In the improved algorithm, initial positions are arranged according to chaotic sequence; therefore, the uniformity and ergodicity of population are enhanced. Adaptive inertia weight is introduced to update the rule of hens; thus, the speed of global search and the ability of local search are enhanced. The following coefficient of chicks is changed into random quantity, so the risk of falling into local extremum is avoided. These improvements enhance the search ability in the early stage and the track ability in the late stage of the algorithm. The improved algorithm is applied in the maximum power point tracking control of the photovoltaic system and is compared with other algorithms.
The relationship between preoperative fetal head circumference and 2‐year cognitive performance after laser surgery for twin‐twin transfusion syndrome
Authors: Chon Andrew H. , Mamey Mary Rose , Schrager Sheree M. , Vanderbilt Douglas L. , Chmait Ramen H. 
Published: January 2018

AbstractObjectiveTo determine the relationship between preoperative fetal head circumference (HC) and cognitive performance among children treated with laser surgery for twin‐twin transfusion syndrome (TTTS).MethodsDonor and recipient twin HCs were measured preoperatively (16–26 weeks' gestation) and at 2 years corrected age. Multilevel multivariate regression models were used to test pregnancy and child‐level risk factors for lower Battelle Developmental Inventory Second Edition (BDI‐2) scores. A repeated‐measures ANOVA was used to examine HC growth among recipients and donors between preoperative and 2 years.ResultsNinety‐nine children were evaluated. The average BDI‐2 score for the cohort was 101.4 (SD = 12.2). After controlling for covariates, larger preoperative HC percentiles were significantly associated with an increase in total BDI‐2 scores (β = 0.29; P < 0.001), where a 12.5% increase in preoperative HC percentile was associated with 1‐point increase in total BDI‐2 score. The mean recipient and donor twin HC percentiles preoperatively and at age 2 years were 51st percentile vs 20th percentile (P = .050) and 60th percentile vs 49th percentile (P = .676), respectively.ConclusionSmaller preoperative HC percentiles identified children at risk of lower, but still within normal range, total BDI‐2 scores. The discordance in HC percentiles between the donor and recipient twin decreased after laser surgery.
Severe fetal hydronephrosis: the added value of associated congenital anomalies of the kidneys and urinary tract (CAKUT) in the prediction of postnatal outcome
Authors: Perlman Sharon , Roitman Lucia , Lotan Danny , Kivilevitch Zvi , Pode‐Shakked Naomi , Pode‐Shakked Ben , Achiron Reuven , Dekel Benjamin , Gilboa Yinon 
Published: January 2018

AbstractObjectiveThe aim of this study was to focus on fetuses diagnosed with severe hydronephrosis and correlate prenatal sonographic characteristics with postnatal outcome.MethodsCases presenting prenatally with severe hydronephrosis (anterior‐posterior renal pelvic diameter >15 mm) were collected retrospectively over a period of 11 years and divided into 2 groups: (1) isolated hydronephrosis and (2) those associated with congenital anomalies of the kidney and urinary tract (CAKUT).ResultsA total of 83 fetuses comprised the study group: 35 fetuses had isolated severe hydronephrosis and 48 had associated CAKUT. The mean anterior‐posterior renal pelvic diameter was 22.6 ± 8.5 mm (range 15.0‐66.0 mm).The CAKUT group was associated with a significantly increased incidence of postnatal need for surgery (17.6% vs 44.2%, P = .014), dysplastic kidney (0% vs 14%, P = .023), and total abnormal outcome (52.9% vs 86%, P = .001) in comparison with isolated severe prenatal hydronephrosis.ConclusionsSevere fetal hydronephrosis has a wide postnatal clinical spectrum, which is mainly influenced by the presence of associated sonographic CAKUT findings. These clinical data have biological relevance: a genetic or environmental defect that influences multiple renal developmental processes leads to hydronephrosis but also to concomitant malformations (CAKUT) and critically influences renal prognosis. A more selective abnormal developmental process that results in isolated enlarged pelvis even to a severe extent has less influence on renal prognosis.
Kinematic investigations on the Furggwanghorn Rock Glacier, Switzerland
Authors: Buchli Thomas , Kos Andrew , Limpach Philippe , Merz Kaspar , Zhou Xiaohai , Springman Sarah M. 
Published: January 2018

AbstractMany thermo‐hydro‐mechanical parameters and their interactions influence the creep behaviour of rock glaciers, with the result that the kinematics of rock glaciers are complex and not fully understood. An interdisciplinary project began in 2010 to investigate the physical ground conditions and any climatic dependence of a fast‐moving rock glacier below the Furggwanghorn peak, in the Turtmann Valley of the Swiss Alps. Remote sensing and subsurface instrumentation (in‐place inclinometers and temperature sensors), together with ground and airborne geophysical methods, reveal the creep rate and the hydrological and thermal conditions of the rock glacier. The Furggwanghorn rock glacier exhibits displacements in the order of metres per year and showed substantial surface changes at a minimal ground temperature slightly below 0°C. A detailed three‐dimensional kinematic ground model shows the internal structure and shear surfaces, indicating past creep behaviour and failure mechanisms. The results suggest that observed seasonal changes in the creep rate of the rock glacier did not depend directly on the temperature at depth, but were very likely controlled by hydrological processes.
Correlations of SELENOF and SELENOP genotypes with serum selenium levels and prostate cancer
Authors: Ekoue Dede N. , Ansong Emmanuel , Liu Li , Macias Virgilia , Deaton Ryan , Lacher Craig , Picklo Matthew , Nonn Larisa , Gann Peter H. , Kajdacsy‐Balla Andre , Prins Gail S. , Freeman Vincent L. , Diamond Alan M. 
Published: January 2018

BackgroundSelenium status is inversely associated with the incidence of prostate cancer. However, supplementation trials have not indicated a benefit of selenium supplementation in reducing cancer risk. Polymorphisms in the gene encoding selenoprotein 15 (SELENOF) are associated with cancer incidence/mortality and present disproportionately in African Americans. Relationships among the genotype of selenoproteins implicated in increased cancer risk, selenium status, and race with prostate cancer were investigated.MethodsTissue microarrays were used to assess SELENOF levels and cellular location in prostatic tissue. Sera and DNA from participants of the Chicago‐based Adiposity Study Cohort were used to quantify selenium levels and genotype frequencies of the genes for SELENOF and the selenium‐carrier protein selenoprotein P (SELENOP). Logistic regression models for dichotomous patient outcomes and regression models for continuous outcome were employed to identify both clinical, genetic, and biochemical characteristics that are associated with these outcomes.ResultsSELENOF is dramatically reduced in prostate cancer and lower in tumors derived from African American men as compared to tumors obtained from Caucasians. Differing frequency of SELENOF polymorphisms and lower selenium levels were observed in African Americans as compared to Caucasians. SELENOF genotypes were associated with higher histological tumor grade. A polymorphism in SELENOP was associated with recurrence and higher serum PSA.ConclusionsThese results indicate an interaction between selenium status and selenoprotein genotypes that may contribute to the disparity in prostate cancer incidence and outcome experienced by African Americans.
Kayak drifter surface velocity observation for 2D hydraulic model validation
Authors: Barker J.R. , Pasternack G.B. , Bratovich P.M. , Massa D.A. , Wyrick J.R. , Johnson T.R. 
Published: January 2018

AbstractAdvances in remote sensing, informatics, software, and microprocessors enable meter‐resolution two‐dimensional (2D) hydrodynamic models that produce nearly a census of ecohydraulic conditions over long river segments with 105 to 108 computational elements. It is difficult to test statistical and spatial model performance at such scope using fixed‐point velocity measurements, because field methods are so expensive, laborious, slow, and restricted by safety factors. This study evaluated low‐cost water surface particle tracking by kayak with real‐time kinematic GPS for 2D model validation using 7.2 km of the lower Yuba River in California. Observed flows were between 15 to 140 m3/s, which were in‐channel up to and including bankfull conditions. The coefficients of determination between 5,780 observations and 2D model predictions were 0.79 and 0.80 for velocity magnitude and direction, respectively. When surface speed was downscaled and compared to modelled depth‐averaged velocity, median unsigned difference was 15.5%. Standard hydrological model performance metrics affirmed satisfactory validation. Surface tracking provided the novel benefit of enabling validation of velocity direction, and that testing found satisfactory performance using all metrics. Having 10 to 1,000 times more data enables robust statistical testing and spatial analysis of both speed and direction, which outweighs the loss of depth‐averaged data. Both fixed‐point and kayak particle tracking methods are useful tools to help evaluate 2D model performance.
Molecular and genetic interactions of the RNA degradation machineries in Firmicute bacteria
Authors: Redder Peter 
Published: January 2018

Correct balance between bacterial RNA degradation and synthesis is essential for controlling expression level of all RNAs. The RNA polymerase, which performs the RNA synthesis, is highly conserved across the bacterial domain. However, this is surprisingly not the case for the RNA degradation machinery, which is composed of different subunits and performs different enzymatic reactions, depending on the organism. In Escherichia coli, the RNA decay is performed by the degradosome complex, which forms around the membrane‐associated endoribonuclease RNase E, and is stable enough to be purified without falling apart. In contrast, many Firmicutes, for example, Bacillus subtilis, Staphylococcus aureus, and Streptococcus pneumoniae, do not encode an RNase E homolog, but instead have the endoribonuclease RNase Y and the exo‐ and endo‐ribonuclease RNase J complex. A wide range of experiments have been performed, mainly with B. subtilis and S. aureus, to determine which interactions exist between the various RNA decay enzymes in the Firmicutes, with the goal of understanding how RNA degradation (and thus gene expression homeostasis and regulation) is organized in these organisms. The in vivo and in vitro data is diverse, and does not always concur. This overview gathers the data on interactions between Firmicute RNA degradation factors, to highlight the similarities and differences between experimental data from different experiments and from different organisms. WIREs RNA 2018, 9:e1460. doi: 10.1002/wrna.1460This article is categorized under:

RNA Turnover and Surveillance > Turnover/Surveillance Mechanisms
RNA Turnover and Surveillance > Regulation of RNA Stability
Past, Present, and Future of Mercury Pollution Issues
Authors: Yokoyama Hisashi 
Published: January 2018

AbstractIn this chapter, countermeasures and solutions to methylmercury poisoning (MPM) and current and outstanding issues on the mercury pollution are discussed. Correct information and data, public access to information, establishment of company ethics, rapid response by governments, societal responsibility, and penalties on responsible organizations are necessary for preventing the similar kind of pollution and human hazard. Recent studies which show the relationship between the anthropogenic emissions of mercury and the risk to human health, especially to fetuses and infants, are summarized. Finally, outstanding issues on MPM that are in connection with the global mercury cycle are discussed.
More Than Talking About the Weekend: Content of Case‐Irrelevant Communication Within the OR Team
Authors: Widmer Lukas W. , Keller Sandra , Tschan Franziska , Semmer Norbert K. , Holzer Eliane , Candinas Daniel , Beldi Guido 
Published: January 2018

AbstractBackgroundCase‐irrelevant communication (CIC) is defined as “any conversation” irrelevant to the case. It includes small talk, but also communication related to other work issues besides the actual task. CIC during surgeries is generally seen as distracting, despite a lack of knowledge about the content of CIC and its regulation in terms of adjustments to the situation of CIC. Primary goal of the study was to evaluate CIC content; secondary goal was to evaluate whether surgical teams regulate CIC according to different concentration demands of surgical procedures.MethodsIn 125 surgeries, 1396 CIC events were observed. CIC were content coded into work‐related CIC (pertaining to other tasks or work in general) and social CIC (pertaining to acquaintance talk, gossip, or private conversation). The impact of different phases and the difficulty of the surgical procedure on CIC were assessed.ResultsWork‐related CIC were significantly more frequent (2.49 per hour, SD = 2.17) than social CIC (1.42 per hour, SD = 2.17). Across phases, frequency of work‐related CIC was constant, whereas social CIC increased significantly across phases. In surgeries assessed as highly difficult by the surgeons, social CIC were observed at a lower frequency, and less work‐related CIC were observed during the main phase compared to surgeries assessed as less difficult.ConclusionThe high proportion of work‐related CIC indicates that surgical teams deal with other tasks during surgeries. Surgical teams adapt CIC according to the demands of the procedure. Hospital policies should support these adaptations rather than attempt to suppress CIC entirely.
Flux analysis of inborn errors of metabolism
Authors: Reijngoud D.‐J. 
Published: January 2018

AbstractPatients with an inborn error of metabolism (IEM) are deficient of an enzyme involved in metabolism, and as a consequence metabolism reprograms itself to reach a new steady state. This new steady state underlies the clinical phenotype associated with the deficiency. Hence, we need to know the flux of metabolites through the different metabolic pathways in this new steady state of the reprogrammed metabolism. Stable isotope technology is best suited to study this. In this review the progress made in characterizing the altered metabolism will be presented. Studies done in patients to estimate the residual flux through the metabolic pathway affected by enzyme deficiencies will be discussed. After this, studies done in model systems will be reviewed. The focus will be on glycogen storage disease type I, medium‐chain acyl‐CoA dehydrogenase deficiency, propionic and methylmalonic aciduria, urea cycle defects, phenylketonuria, and combined D,L‐2‐hydroxyglutaric aciduria. Finally, new developments are discussed, which allow the tracing of metabolic reprogramming in IEM on a genome‐wide scale. In conclusion, the outlook for flux analysis of metabolic derangement in IEMs looks promising.
A Relation Aware Search Engine for Materials Science
Authors: Shah Sapan , Vora Dhwani , Gautham B. P. , Reddy Sreedhar 
Published: January 2018

AbstractKnowledge of material properties, microstructure, underlying material composition, and manufacturing process parameters that the material has undergone is of significant interest to materials scientists and engineers. A large amount of information of this nature is available in publications in the form of experimental measurements, simulation results, etc. However, getting to the right information of this kind that is relevant for a given problem on hand is a non-trivial task. First, an engineer has to go through a large collection of documents to select the right ones. Then, the engineer has to scan through these selected documents to extract relevant pieces of information. Our goal is to help automate some of these steps. Traditional search engines are not of much help here, as they are keyword centric and weak on relation processing. In this paper, we present a domain-specific search engine that processes relations to significantly improve search accuracy. The engine preprocesses material publication repositories to extract entities such as material compositions, material properties, manufacturing processes, process parameters, and their values and builds an index using these entities and values. The engine then uses this index to process user queries to retrieve relevant publication fragments. It provides a domain-specific query language with relational and logical operators to compose complex queries. We have conducted an experiment on a small library of publications on steel on which searches such as “get the list of publications which have carbon composition between 0.2 and 0.3 and on which tempering is carried out for about 30 to 40 min” are performed. We compare the results of our search engine with the results of a keyword-based search engine.