bluuebunny/crossref_metadata_2025_split huggingface dataset:
Programmed to Fail? On the Limits of Inscription and the Generality of Writing
Authors: Goldgaber Deborah 
Published: August 2017

ABSTRACT
In Of Grammatology, Derrida asserts the absolute generality of the trace, arguing that it pertains to life and its material basis. However, it has been difficult for Derrida's interpreters to identify the warrant for this generality claim. Recently, Martin Hägglund has offered an influential defense of the generality of the trace by grounding it in the form of finite life (survival). However, as Catherine Malabou's critique of the grammatological project suggests, any such attempt is programmed to fail. On her view, writing never was and never could be general; by linking the trace to the model of writing or inscription, Derrida limited the generality of the trace and its pertinence for any philosophical materialism. Materiality, Malabou argues, is what will always necessarily escape every model of inscription. To think the generality of the trace requires thinking a nongraphic trace. Insofar as Malabou's notion of “plasticity” does this, it should be understood as heir to Derrida's notion of writing. However, I argue, Derrida's notion of “writing” was always already nongraphic, or plastic in a way that Malabou and other interpreters have failed to factor.
Initiating Life: Agamben and the Political Use of Intimacy
Authors: Bordeleau Erik 
Published: August 2017

ABSTRACT
What does it mean to initiate life? According to Giorgio Agamben, the question of initiating life concerns how we conceive and experiment with the “how” of a form of life. In short, it involves ways of envisaging an absolutely immanent life on the threshold of its political and ethical intensification. To follow Agamben's paradigmatic problematization, an initiated life is a life made inextricable from its manner or form—a form-of-life. It is within this practical and ethopoietical horizon of thought that I envisage Agamben's work here, on the lookout for what I call “signs of passion.” Signs of passion are what an initiated life is composed of; they are inherently precarious and participate in a political use of intimacy in which a form-of-life nurtures and preserves its sense of nonknowledge and the generative limits of its own (absence of) mystery.
De gelijkwaardige voorziening: geen gezeik iedereen rijk?
Authors: Jansen Niels 
Published: August 2017

De gelijkwaardige voorziening: geen gezeik iedereen rijk?
De gelijkwaardige voorziening leek na anderhalf jaar Wwz veroordeeld tot een anoniem bestaan, maar niets blijkt minder waar. De oogst van het huidige kalenderjaar tot heden: vijf uitspraken en een controversieel verklaard wetsvoorstel. Al met al genoeg reden deze rechtsfiguur aan een nader onderzoek te onderwerpen. In deze bijdrage worden onder meer enkele voor de praktijk relevante knelpunten besproken.
A Statistical Review of Alternative Zinc and Copper Extraction from Mineral Fertilizers and Industrial By-Products
Authors: Cenciani de Souza Camila Prado , Aparecida de Abreu Cleide , Coscione Aline Renée , Alberto de Andrade Cristiano , Teixeira Luiz Antonio Junqueira , Consolini Flavia 
Published: August 2017

Abstract
Rapid, accurate, and low-cost alternative analytical methods for micronutrient quantification in fertilizers are fundamental in QC. The purpose of this study was to evaluate whether zinc (Zn) and copper (Cu) content in mineral fertilizers and industrial by-products determined by the alternative methods USEPA 3051a, 10% HCl, and 10% H2SO4 are statistically equivalent to the standard method, consisting of hot-plate digestion using concentrated HCl. The commercially marketed Zn and Cu sources in Brazil consisted of oxides, carbonate, and sulfate fertilizers and by-products consisting of galvanizing ash, galvanizing sludge, brass ash, and brass or scrap slag. The contents of sources ranged from 15 to 82% and 10 to 45%, respectively, for Zn and Cu. The Zn and Cu contents refer to the variation of the elements found in the different sources evaluated with the concentrated HCl method as shown in Table 1. A protocol based on the following criteria was used for the statistical analysis assessment of the methods: F-test modified by Graybill, t-test for the mean error, and linear correlation coefficient analysis. In terms of equivalents, 10% HCl extraction was equivalent to the standard method for Zn, and the results of the USEPA 3051a and 10% HCl methods indicated that these methods were equivalents for Cu. Therefore, these methods can be considered viable alternatives to the standard method of determination for Cu and Zn in mineral fertilizers and industrial by-products in future research for their complete validation.
Development and Validation of an HPLC–UV Method to Quantify Tavaborole During in Vitro Transungual Permeation Studies
Authors: Tampucci Silvia , Terreni Eleonora , Burgalassi Susi , Chetoni Patrizia , Monti Daniela 
Published: August 2017

Abstract
A selective and rapid reversed-phase HPLC–UV method was developed and validated to quantify tavaborole (TAV; AN2690) in biological samples, i.e., in receiving phase and in bovine hoof membrane extract derived from in vitro transungual permeation studies. A simple solid–liquid extraction procedure was used to recover the drug from the bovine hoof slices. TAV chromatographic separation was achieved on a Luna PFP column (150 × 4.6 mm, 5 μm) using a mobile phase consisting of a 70% phosphoric acid solution (10 mM, pH 2.0) with 30% acetonitrile. The detection wavelength was set to 220 nm using a UV detector. The method exhibited good linearity in the calibration ranges, which were 0.5–8.0 and 0.03–2.5 μg/mL for the receiving phase and hoof membranes, respectively. The obtained LOD and LOQ values were 0.023 and 0.069 μg/mL, respectively, for the receiving phase and 0.0024 and 0.007 μg/mL for the bovine hoof membrane extracts. In all cases, the CV for intraday and interday precision was widely below the limit of 2%, demonstrating good precision. The analytical method described was sensitive, precise, linear, and accurate and could be applicable for clinical and bioanalytical studies as an alternative to other analytical methods, which are quite expensive and not always available in research laboratories.
Novel Approach for the Simultaneous Determination of Carbinoxamine Maleate, Pholcodine, and Ephedrine Hydrochloride Without Interference from Coloring Matter in an Antitussive Preparation Using Smart Spectrophotometric Methods
Authors: Moustafa Azza A , Hegazy Maha A , Mohamed Dalia , Ali Omnia 
Published: August 2017

Abstract
The presence of coloring matters in syrups usually interferes with the spectrophotometric determination of active pharmaceutical ingredients. A novel approach was introduced to eliminate the interference of sunset yellow (coloring matter) in Cyrinol syrup. Smart, simple, accurate, and selective spectrophotometric methods were developed and validated for the simultaneous determination of a ternary mixture of carbinoxamine maleate, pholcodine, and ephedrine hydrochloride in syrup. Four of the applied methods used ratio spectra: successive derivative subtraction coupled with constant multiplication, successive derivative of ratio spectra, ratio subtraction coupled with ratio difference, and ratio spectra continuous wavelet transforms zero-crossing. In addition, a method that was based on the presence of an isosbestic point, the amplitude summation method, was also established. A major advantage of the proposed methods is the simultaneous determination of the mentioned drugs without prior separation steps. These methods were successfully applied for the determination of laboratory-prepared mixtures and a commercial pharmaceutical preparation without interference from additives, thus proving the selectivity of the methods. No significant difference regarding both accuracy and precision was observed upon statistical comparison of the results obtained by the proposed methods with each other and with those of official or reported ones.
An HPLC Method for the Determination of Isoflavones and the Evaluation of Their Antioxidant Capacity in Both Homogeneous and Microheterogeneous Systems
Authors: Montero Guillermo , Günther Germán , Valdés Karina , Arriagada Francisco , Morales Javier 
Published: August 2017

Abstract
In this work, we developed an HPLC method to simultaneously quantify and hence evaluate the stability, distribution, and antioxidant capacity of six isoflavones: genistein, genistin, daidzein, daidzin, glycitin, and biochanin A. Isoflavones have been described as having an important estrogenic activity to treat menopausal symptoms and can reduce postmenopausal bone loss and also participate in the prevention of cardiovascular diseases. These beneficial properties are believed derived from their capacity to act as free-radical scavengers. Isoflavones are formulated in capsules and creams and also can be used as antioxidants in liposomes. HPLC separation was achieved on an Agilent Hypersil ODS C18 column. The mobile phase consisted of 0.02–0.2% orthophosphoric acid in water–acetonitrile with gradient elution. The diode array detector was operated at 260 nm. The hydrophobicity of isoflavones was determined through their distribution in octanol–buffer. These results allowed us to establish a relation between chemical structure, pKa, lipophilicity, and the characteristics of the dispersion medium. Photolysis of hydrogen peroxide was used to measure the HO• scavenging capability of isoflavones. In liposomes, the order of reactivity of the studied compounds was genistein &gt; biochanin A &gt; genistin &gt; daidzein &gt; daidzin &gt; glycitin.
General Steps to Standardize the Laboratory Measurement of Serum Total 25-Hydroxyvitamin D
Authors: Sempos Christopher T , Betz Joseph M , Camara Johanna E , Carter Graham D , Cavalier Etienne , Clarke Michael W , Dowling Kirsten G , Durazo-Arvizu Ramon A , Hoofnagle Andrew N , Liu Andy , Phinney Karen W , Sarafin Kurtis , Wise Stephen A , Coates Paul M 
Published: August 2017

Abstract
The Vitamin D Standardization Program (VDSP) has collaborated with numerous groups and agencies to assemble a set of tools, i.e., a reference measurementsystem, that can be used to establish the traceability of 25-hydroxyvitamin D [25(OH)D] assays to relevant reference measurement procedures and reference materials. This is done with the goal of verifying end-user laboratory performance using precise statistical criteria to determine whether a specific assay isstandardized. The purpose of this paper was to outline a set of steps that routine clinical and researchlaboratories can use to standardize their 25(OH)D assays using these tools. These steps apply to laboratories using commercially developed immunoassay measurement systems as well as in-house assays, usually based on high HPLC or LC tandem MS measurement systems. The steps are (1) initial calibration, (2) initial assessment of accuracy and bias, (3) assessment of total percent CV and mean bias, (4)use of trueness controls, and (5) participation in accuracy-based performance testing and/or external quality assessment schemes. The goal of each laboratory assay is to have a total CV of ≤10% and mean bias of ≤5%. Rigorous and less rigorous but low-cost options for meeting thesestatistical criteria are provided. Research laboratories who infrequently measure 25(OH)D are advised torepeat steps 1–4 for every measurement cycle.For users of commercial immunoassays who have relatively little control over standardization, we presentan option for using trueness controls to develop a master equation that can be used to standardize results to the reference methods.
A posição do Brasil em face da decisão da OMC: uma decisão realista ou racionalista sob a perspectiva da Escola das Três Tradições?
Authors: Vaciles Bilacchi Júnior Gilberto 
Published: August 2017

O presente ar go tem por obje vo analisar, com base nas diferentes correntes teóricas do direi- to internacional, como se dá a tomada de decisões dos países no âmbito das relações internacionais. Começaremos por uma análise do mundo jurídico e do mundo polí co, e a forma como estão organizados os países atualmente reconhecidos pela Organização das Nações Unidas. Posteriormente, adentraremos as relações internacionais e as suas teorias, analisando as principais correntes de pensamento que são o liberalismo, o realismo, a teoria radical e a economia polí ca internacional. O destaque será dado para a Escola das Três Tradições, que se baseia nos conceitos de Hedley Bull e Martin Wight de três tradições de ação no ambiente internacional. Para facilitar a compreensão do tema, u lizaremos como exemplo a disputa comercial acer- ca dos subsídios agrícolas, travada entre o Brasil e os Estados Unidos da América, perante a Organização Mundial do Comércio. Ao m, concluiremos opinando pelo po de decisão tomada pelo governo brasileiro ao rmar acordo com o país norte-americano acerca da disputa comercial, e em qual das teorias analisadas mais se amolda o atual estágio das relações internacionais.
Conselhos Setoriais como elementos de formulação de políticas públicas
Authors: Losso Marcelo Ribeiro 
Published: August 2017

O presente trabalho trata do estudo dos Conselhos Setoriais como instrumentos de formulação de políticas públicas no Brasil. O Estado afasta-se da posição de império passando para a posição de consenso, interagindo com um número crescente de atores sociais. Os movimentos sociais no país nas últimas décadas, em especial aqueles que buscavam maior participação política, foram importantes para a abertura de canais de participação da sociedade civil na formulação de políticas públicas. Previsões constitucionais e legais permitem a participação da sociedade e o direcionamento das políticas públicas num sistema pautado no debate público, plural e paritário entre os diversos atores sociais. Os Conselhos Setoriais são instrumentos privilegiados de formulação das políticas públicas, contudo, apresentam limitações e desaos para que sejam alcançadas a eficácia e a efetividade desejadas para esses instrumentos.
Essential literature for the chiropractic profession: Results and implementation challenges from a survey of international chiropractic faculty
Authors: Mansholt Barbara A. , Salsbury Stacie A. , Corber Lance G. , Stites John S. 
Published: August 2017

Objective:
Scientific literature applicable to chiropractic practice proliferates in quantity, quality, and source. Chiropractic is a worldwide profession and varies in scope between states or provinces and from country to country. It is logical to consider that the focus and emphasis of chiropractic education varies between programs as well. This original research study endeavored to determine “essential literature” recommended by chiropractic faculty. The purpose of this article is (1) to share our results and (2) to promote discussion and explore means for future collaboration of chiropractic faculty through a worldwide platform.

Methods:
A 2-phase recruitment occurred initially at the institutional level and subsequently at the faculty level. A Web-based survey used qualitative data collection methods to gather bibliographic citations. Descriptive statistics were calculated for demographics, and citation responses were ranked per number of recommendations, grouped into categories, and tabulated per journal source and publication date.

Results:
Forty-one chiropractic programs were contacted, resulting in 30 participating chiropractic programs (16 US and 14 international). Forty-five faculty members completed the entire survey, submitting 126 peer-reviewed publications and 25 additional citations. Readings emphasized clinical management of spine pain, the science of spinal manipulation, effectiveness of manual therapies, teaching of chiropractic techniques, outcomes assessments, and professional issues.

Conclusion:
A systematic approach to surveying educators in international chiropractic institutions was accomplished. The results of the survey provide a list of essential literature for the chiropractic profession. We recommend establishing a chiropractic faculty registry for improved communication and collaboration.
Nitrogen enrichment and speciation in a coral reef lagoon driven by groundwater inputs of bird guano
Authors: McMahon Ashly , Santos Isaac R. 
Published: August 2017

AbstractWhile the influence of river inputs on coral reef biogeochemistry has been investigated, there is limited information on nutrient fluxes related to submarine groundwater discharge (SGD). Here, we investigate whether significant saline groundwater‐derived nutrient inputs from bird guano drive coral reef photosynthesis and calcification off Heron Island (Great Barrier Reef, Australia). We used multiple experimental approaches including groundwater sampling, beach face transects, and detailed time series observations to assess the dynamics and speciation of groundwater nutrients as they travel across the island and discharge into the coral reef lagoon. Nitrogen speciation shifted from nitrate‐dominated groundwater (>90% of total dissolved nitrogen) to a coral reef lagoon dominated by dissolved organic nitrogen (DON; ∼86%). There was a minimum input of nitrate of 2.1 mmol m−2 d−1 into the lagoon from tidally driven submarine groundwater discharge estimated from a radon mass balance model. An independent approach based on the enrichment of dissolved nutrients during isolation at low tide implied nitrate fluxes of 5.4 mmol m−2 d−1. A correlation was observed between nitrate and daytime net ecosystem production and calcification. We suggest that groundwater nutrients derived from bird guano may offer a significant addition to oligotrophic coral reef lagoons and fuel ecosystem productivity and the coastal carbon cycle near Heron Island. The large input of groundwater nutrients in Heron Island may serve as a natural ecological analogue to other coral reefs subject to large nutrient inputs from anthropogenic sources.
Slow acidification of the winter mixed layer in the subarctic western North Pacific
Authors: Wakita Masahide , Nagano Akira , Fujiki Tetsuichi , Watanabe Shuichi 
Published: August 2017

AbstractWe used carbon dioxide (CO2) system data collected during 1999–2015 to investigate ocean acidification at time series sites in the western subarctic region of the North Pacific Ocean. The annual mean pH at station K2 decreased at a rate of 0.0025 ± 0.0010 year−1 mostly in response to oceanic uptake of anthropogenic CO2. The Revelle factor increased rapidly (0.046 ± 0.022 year−1), an indication that the buffering capacity of this region of the ocean has declined faster than at other time series sites. In the western subarctic region, the pH during the winter decline at a slower rate of 0.0008 ± 0.0004 year−1. This was attributed to a reduced rate of increase of dissolved inorganic carbon (DIC) and an increase of total alkalinity (TA). The reduction of DIC increase was caused by the decline of surface water density associated with the pycnocline depression and the reduction of vertical diffusion flux from the upper pycnocline. These physical changes were probably caused by northward shrinkage of the western subarctic gyre and global warming. Meanwhile, the contribution of the density decline to the TA increase is canceled out by that of the reduced vertical diffusive flux. We speculated that the winter TA increase is caused mainly by the accumulation of TA due to the weakened calcification by organisms during the winter.
Importance of coccolithophore‐associated organic biopolymers for fractionating particle‐reactive radionuclides (234Th, 233Pa, 210Pb, 210Po, and 7Be) in the ocean
Authors: Lin Peng , Xu Chen , Zhang Saijin , Sun Luni , Schwehr Kathleen A. , Bretherton Laura , Quigg Antonietta , Santschi Peter H. 
Published: August 2017

AbstractLaboratory incubation experiments using the coccolithophore Emiliania huxleyi were conducted in the presence of 234Th, 233Pa, 210Pb, 210Po, and 7Be to differentiate radionuclide uptake to the CaCO3 coccosphere from coccolithophore‐associated biopolymers. The coccosphere (biogenic calcite exterior and its associated biopolymers), extracellular (nonattached and attached exopolymeric substances), and intracellular (sodium‐dodecyl‐sulfate extractable and Fe‐Mn‐associated metabolites) fractions were obtained by sequentially extraction after E. huxleyi reached its stationary growth phase. Radionuclide partitioning and the composition of different organic compound classes, including proteins, total carbohydrates (TCHO), and uronic acids (URA), were assessed. 210Po was closely associated with the more hydrophobic biopolymers (high protein/TCHO ratio, e.g., in attached exopolymeric substances), while 234Th and 233Pa showed similar partitioning behavior with most activity being distributed in URA‐enriched, nonattached exopolymeric substances and intracellular biopolymers. 234Th and 233Pa were nearly undetectable in the coccosphere, with a minor abundance of organic components in the associated biopolymers. These findings provide solid evidence that biogenic calcite is not the actual main carrier phase for Th and Pa isotopes in the ocean. In contrast, both 210Pb and 7Be were found to be mostly concentrated in the CaCO3 coccosphere, likely substituting for Ca2+ during coccolith formation. Our results demonstrate that even small cells (E. huxleyi) can play an important role in the scavenging and fractionation of radionuclides. Furthermore, the distinct partitioning behavior of radionuclides in diatoms (previous studies) and coccolithophores (present study) explains the difference in the scavenging of radionuclides between diatom‐ and coccolithophore‐dominated marine environments.
Coccolithophore variability across Marine Isotope Stage 11 in the Pacific sector of the Southern Ocean and its potential impact on the carbon cycle
Authors: Saavedra‐Pellitero Mariem , Baumann Karl‐Heinz , Lamy Frank , Köhler Peter 
Published: August 2017

AbstractProxy‐based reconstructions of past changes in the marine biological carbon pumps are limited, especially in the Southern Ocean. This work provides new insights into the productivity variations in the Pacific sector of the Southern Ocean. We present new data derived from three sediment cores that show glacial/interglacial coccolithophore variability across Marine Isotope Stage 11 (MIS 11). The cores were retrieved during R/V Polarstern cruise PS75 from the Subantarctic Zone and Polar Front Zone at the western flank of the East Pacific Rise and in the vicinity of the Antarctic‐Pacific Ridge. Coccolithophore assemblages were overwhelmingly dominated by the species Gephyrocapsa caribbeanica and small Gephyrocapsa. Total numbers of coccoliths, coccolith accumulation rates, coccolith fraction (CF; <20 μm fraction) Sr/Ca data, and temperature‐corrected CF Sr/Ca records consistently showed an increase in coccolithophore productivity during Termination V (MIS 12‐11 boundary), highest productivity throughout MIS 11 (~424–374 kyr), and a decrease during late MIS 11 in all the cores. We end with a discussion of back‐calculated coccolith calcification rate in the surface ocean and its potential contribution to changes in the concentration of atmospheric CO2.