bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autologous Collagen-Induced Chondrogenesis Technique for Knee Chondral Lesions
Authors: Costa-Paz Matias , Zicaro Juan Pablo , Yacuzzi Carlos 
Published: January 2017

Objectives: The purpose of the study was to evaluate a series of patients with osteochondral lesions who underwent a microfractures treatment and autologous collagen-induced chondrogenesis technique (ACIC). Methods: Microfracture treatment and ACIC was performed in eight patients with grade IV cartilage lesion of more than 3 cm2 long. Two patients were discarded due to short follow-up. Four women and two men were evaluated with 50 year-old mean age. The average follow-up was 12.5 months. An associated valgus osteotomy was performed in two patients. Patients were evaluated using the Lysholm score and IKDC. Radiographs were evaluated and a Magnetic Resonance (MRI) was performed in 3 patients. Results: Six patients were evaluated with a 1 B, 2 C and 3 D arthrosis grade according to IKDC classification. Atelocollagen was placed in the medial femoral condyle in four patients (2 associated to tibial valgus osteotomy), in the trochlea in one patient and in both in one patient. Pre and post operative average score IKDC was 38/58 and Lysholm 34/89. One case of postoperative artrofibrosis was registered which was mobilized under anesthesia with satisfactory results. The MRI showed signal with coverage of the chondral defect in more than 70%. There were no cases of infection or reactive synovitis. Conclusion: Atelocollagen combined with microfractures improved the clinical conditions in patients with articular cartilage lesions of the knee. It is necessary more patients and longer follow-up to verify this data.
Giant cell tumor in adipose package Hoffa
Authors: Etcheto H. Rivarola , Escobar G. , Blanchod C. Collazo , Palanconi M. , Zordan J. , Salinas E. Alvarez , Autorino₁ Carlos 
Published: January 2017

Tumors of adipose Hoffa package are very uncommon, with isolated cases reported in the literature. His presentation in pediatric patients knee is exceptional. The most frequently described tumors are benign including vellonodular synovitis. The extra-articular localized variant there of is known as giant cell tumor of the tendon sheath. It is characterized by locally aggressive nature, and has been described in reports of isolated cases. Objective: A case of giant cell tumor of the tendon sheath in adipose presentation package Hoffa in pediatric patients is presented in this paper. Methods: male patient eleven years with right knee pain after sports practice was evaluated. Physical examination, showed limited extension -30º, joint effusion, stable negative Lachman maneuver without peripheral knee laxity. MRI hyperintense on tumor is observed in T2 and hypointense on T1 homogeneous and defined edges content displayed prior to LCA related to adipose Hoffa package. Results: The tumor specimen was obtained and histopathology is defined as densely cellular tissue accumulation of xantomisados fibrocollagenous with histiocytes and multinucleated giant cells, compatible with giant cell tumor of tendon sheath. Conclusion: The presentation of giant cell tumors of the tendon sheath in Hoffa fat pad is exceptional. However, his suspicion allows adequate preoperative surgical planning, as a whole resection is the only procedure that has been shown to decrease the rate of recurrence of this disease.
The complete genome sequence of the yogurt isolate Streptococcus thermophilus ACA-DC 2
Authors: Alexandraki Voula , Kazou Maria , Blom Jochen , Pot Bruno , Tsakalidou Effie , Papadimitriou Konstantinos 
Published: January 2017

AbstractStreptococcus thermophilus ACA-DC 2 is a newly sequenced strain isolated from traditional Greek yogurt. Among the 14 fully sequenced strains of S. thermophilus currently deposited in the NCBI database, the ACA-DC 2 strain has the smallest chromosome, containing 1,731,838 bp. The annotation of its genome revealed the presence of 1,850 genes, including 1,556 protein-coding genes, 70 RNA genes and 224 potential pseudogenes. A large number of pseudogenes were identified. This was also accompanied by the absence of pathogenic features suggesting evolution of strain ACA-DC 2 through genome decay processes, most probably due to adaptation to the milk ecosystem. Analysis revealed the existence of one complete lactose-galactose operon, several proteolytic enzymes, one exopolysaccharide cluster, stress response genes and four putative antimicrobial peptides. Interestingly, one CRISPR-cas system and one orphan CRISPR, both carrying only one spacer, were predicted indicating low activity or inactivation of the cas proteins. Nevertheless, four putative restriction-modification systems were determined that may compensate any deficiencies of the CRISPR-cas system. Furthermore, whole genome phylogeny indicated three distinct clades within S. thermophilus. Comparative analysis among selected strains representative for each clade, including strain ACA-DC 2, revealed a high degree of conservation at the genomic scale, but also strain specific regions. Unique genes and genomic islands of strain ACA-DC 2 contained a number of genes potentially acquired through horizontal gene transfer events, that could be related to important technological properties for dairy starters. Our study suggests genomic traits in strain ACA-DC 2 compatible to the production of dairy fermented foods.
Genomic analysis of four strains of Corynebacterium pseudotuberculosis bv. Equi isolated from horses showing distinct signs of infection
Authors: Baraúna Rafael A. , Ramos Rommel T. J. , Veras Adonney A. O. , de Sá Pablo H. C. G. , Guimarães Luís C. , das Graças Diego A. , Carneiro Adriana R. , Edman Judy M. , Spier Sharon J. , Azevedo Vasco , Silva Artur 
Published: January 2017

AbstractThe genomes of four strains (MB11, MB14, MB30, and MB66) of the species Corynebacterium pseudotuberculosis biovar equi were sequenced on the Ion Torrent PGM platform, completely assembled, and their gene content and structure were analyzed. The strains were isolated from horses with distinct signs of infection, including ulcerative lymphangitis, external abscesses on the chest, or internal abscesses on the liver, kidneys, and lungs. The average size of the genomes was 2.3 Mbp, with 2169 (Strain MB11) to 2235 (Strain MB14) predicted coding sequences (CDSs). An optical map of the MB11 strain generated using the KpnI restriction enzyme showed that the approach used to assemble the genome was satisfactory, producing good alignment between the sequence observed in vitro and that obtained in silico. In the resulting Neighbor-Joining dendrogram, the C. pseudotuberculosis strains sequenced in this study were clustered into a single clade supported by a high bootstrap value. The structural analysis showed that the genomes of the MB11 and MB14 strains were very similar, while the MB30 and MB66 strains had several inverted regions. The observed genomic characteristics were similar to those described for other strains of the same species, despite the number of inversions found. These genomes will serve as a basis for determining the relationship between the genotype of the pathogen and the type of infection that it causes.
From the Desert to the Refuge
Authors: Stanwood Owen 
Published: January 2017

AbstractThis article follows the transatlantic journey of a minister named Jean-Louis Gibert and through his story illuminates an unexplored chapter in French Atlantic history. A Protestant minister from Languedoc, Gibert worked to create Protestant churches in Saintonge, but during the 1760s he fled France, moving first to England and eventually to South Carolina, where he and several hundred Huguenot refugees founded the frontier town of New Bordeaux. Gibert's story illustrates the global nature of eighteenth-century French Protestantism, divided as it was between those who stayed in the French “Desert” and those who found new lives as refugees. Like other Huguenots, Gibert first hoped to use emigration as a political strategy to force concessions from Louis XV. When this strategy failed, the minister and his neighbors left France entirely, promoting themselves as perfect immigrants who would use their skills to develop the British Empire.Cet article suit le voyage transatlantique d'un pasteur protestant nommé Jean-Louis Gibert pour éclaircir un chapitre méconnu de l'histoire de l'Atlantique français. Languedocien d'origine et engagé dans la construction d'églises protestantes à Saintonge, Gibert décida de fuir la France pendant les années 1760, d'abord pour l'Angleterre et finalement en Caroline du Sud, où il fonda la ville frontalière de New Bordeaux avec plusieurs centaines d'autres réfugiés huguenots. L'histoire de Gibert illustre le caractère global du protestantisme français au dix-huitième siècle, partagé entre ceux qui tentèrent une traversée clandestine du « Désert » français, et ceux qui choisirent l'émigration. Comme d'autres huguenots, Gibert espérait initialement utiliser son émigration pour arracher des concessions à Louis XV. Lorsque ce projet politique échoua, le pasteur et ses proches quittèrent définitivement la France, optant finalement pour une image d'émigrés parfaits prêts à mettre leurs compétences au service de l'Empire britannique.
Between Habbakuk and Locke: Pain, Debt, and Economic Subjectivation inParadise Lost
Authors: Im Seo Hee 
Published: January 2017

AbstractReaders of Paradise Lost have argued that the epic registers England’s nascent imperialism negatively through its associations of trade with Satan. This essay rethinks Paradise Lost’s relation to empire by tracing its involvement in the making of an early modern subjectivity that is constitutively informed by an awareness of debt, debit, and credit. That profane mode of thought later finds more enthusiastic expression in the early English novels of Daniel Defoe and others, but it begins to take shape in Milton, who derives it from none other than religious sources such as scripture, atonement theology, and nostalgia for purgatory. Despite its voiced misgivings about British commercialism, Paradise Lost thus participates in England’s historical growth from peripheral island to sprawling world empire.
Obtaining information on the Q-structure of the southern Aegean subduction area by spectral slopes from temporary and permanent networks.
Authors: Ventouzi Ch. , Papazachos C. , Papaioannou Ch. , Hatzidimitriou P. , EGELADOS Working group 
Published: January 2017

Anelastic attenuation studies have been considered one of the main controlling factors affecting seismic wave propagation, providing important information on the earth’s structure. In order to investigate the attenuation structure of the southern Aegean subduction area, we employed ~400 intermediate depth earthquakes recorded by temporary and permanent networks. Using the recorded waveforms we have calculated a frequency-independent path attenuation operator t* for both P and S waves. Initially an automated method was employed, where t* was automatically calculated by the slope of the acceleration spectrum produced above the corner frequency, fc. Computations were performed in the 0.2-25Hz frequency band, using only spectra with a signal to noise ratio greater than 3, and above the noise level for at least the range 1-4Hz (for S and P waves, respectively). In the second approach, the selection of the segment of the spectrum was carried out manually for optimum fitting. No considerable linear trend revealing dependence of t* with distance could be observed on the original data, whereas strong clustering for different focal depth ranges was observed. The spatial variation of the obtained t* values shows that, in general, along arc stations present low values of t*, while bac k-arc stations show much larger values. The observed t* difference becomes more pronounced as the depth of the earthquakes increases, suggesting a significant localized effect of the high -attenuation (low-Q) mantle wedge, in agreement with independent observation.
Using remote sensing multispectral data and GIS techniques for the geological mapping of Halki Island
Authors: Nikolakopoulos K. G. , Tsombos P. I. , Photiades A. , Psonis K. , Zervakou A. 
Published: January 2017

In this paper we present the combined use of remote sensing and GIS techniques for the geological mapping of Halki Island at 1/50.000 scale. The geological formations, geotectonic units and tectonic structures were recognized in situ and mapped. Interpretation of multispectral satellite images (Landsat TM & ETM and Terra ASTER) has been carried out in order to detect the linear or not structures of the study area. Different band ratio was also used in order to distinguish and map the limits of the different geotectonic units. The in situ mapping was enhanced with data derived from the digital processing of the satellite data. All the analogical and digital data were imported in a geodatabase specially designed for geological data. After the necessary topological control and corrections, the data were unified and processed in order to create the final map layout at 1/50.000 scale.
Association between pathogenesis of atherosclerosis and osteoporosis
Authors: Verbovoy Andrey , Mitroshina Ekaterina , Pashentseva Anna 
Published: January 2017

Currently, the leading place in the structure of morbidity in older people takes the cardiovascular disease. It is also the leading cause of death in developed countries. The significance of osteoporosis is now also due to the high and growing prevalence of this pathology. Osteoporotic fractures are associated with a reduction in the quality of life in patients, lead to disability, require a significant investment. This pathology is ranked fourth in the structure of mortality after cardiovascular disease, oncopathology, and diabetes.Numerous studies indicate that these two diseases are associated not only with the occurrence of age, but have common pathogenetic mechanisms. The data obtained suggest that osteoporosis, calcification of the aorta and heart valves and atherosclerotic vascular disease – related pathological processes. Vascular and bone have some common morphological properties, vascular calcification and consists of the same components as the bone tissue.From the standpoint of modern medicine it is extremely important to identify specific relationships between diseases and their common pathogenetic mechanisms for development of a comprehensive and individual approach to the diagnosis, treatment and prevention.
Local Ecological Knowledge on Forest Clearing: A Case Study of Parak and Rimbo Practices in Simancuang Community, Indonesia
Authors: Asmin Ferdinal , Darusman Dudung , Ichwandi Iin , Suharjito Didik 
Published: January 2017

Local communities are frequently judged as the main driver of forest degradation and deforestation because of the weak recognition to local ecological knowledge (LEK) or traditional ecological knowledge (TEK). We assessed that it is important to elaborate the attributes of LEK and TEK as a way to describe why and how the local community clears the forest, as well as its relation to local practices, named parak and rimbo. Our research uses case study method to describe the local practices in Simancuang community, Alam Pauh Duo Village, South Solok District, West Sumatra Province. We conducted unstructured interviews, observations, and documents selection which were analyzed through categorization and codification as well as complemented with history analysis, spatial analysis, and related document analysis. The results showed that Simancuang community knowledge can describe the attributes of LEK and TEK as a unified whole of local knowledge for sustaining their livelihoods. Therefore, the forest clearing by Simancuang people is one of the livelihoods strategies, but they were not the main driver of forest degradation and deforestation in South Solok District.
High-sensitive basal serum thyroglobulin 6–12 months after thyroid ablation is strongly associated with early response to therapy and event-free survival in patients with low-to-intermediate risk differentiated thyroid carcinomas
Authors: Trimboli P , Zilioli V , Imperiali M , Ceriani L , Giovanella L 
Published: January 2017

Objective
High-sensitive thyroglobulin assays (hsTg) has decreased the need for stimulated Tg measurements in patients with differentiated thyroid carcinoma (DTC). However, multiple assays analyzing the same samples may report different values. Accordingly, appropriate assay-specific cut-off levels should be selected in representative patient series. Here, we evaluate the role of a new hsTg assay in low-to-intermediate risk DTC patients and select appropriate assay-specific clinical cut-off limits.

Design
This was a retrospective study. The response to treatment was assessed according to ATA.

Methods
Patients with low-to-intermediate risk DTC treated and regularly followed-up in our thyroid center. Tg was measured on the Kryptor Compact Plus Instrument (BRAHMS Thermo Fisher Scientific).

Results
The study series comprised 201 DTC patients and excellent response (ER) was demonstrated in 184 (91.5%). Optimized threshold of basal Tg (onT4-Tg) measured 6–12 months after initial treatment was set by ROC curves analysis at 0.28 ng/mL. Having onT4-Tg <0.28 ng/mL at 6–12 months after treatment was associated with longer disease-free survival of Kaplan–Meier (P < 0.001), ER at early follow-up (odds ratio (OR): 165, P < 0.001) and absence of relapse during follow-up (OR: 328, P = 0.0001).

Conclusions
Patients with low- and intermediate-risk DTC could be considered cured when they have onT4-Tg levels <0.28 ng/mL coupled with negative imaging at their first post-ablation visit.
Legitimidade da polícia: segurança pública para além da dissuasão
Authors: Zanetic André , Manso Bruno Paes , Natal Ariadne Lima , Oliveira Thiago Rodrigues 
Published: January 2017

As políticas de segurança pública no Brasil vêm sendo dominadas pelo modelo da teoria da dissuasão, a partir da crença na eficácia de medidas como a intensificação do patrulhamento policial ostensivo, o aumento das redes de vigilância e controle e o crescimento das prisões em flagrante. No entanto, a literatura internacional tem mostrado como uma polícia que vise à obediência normativa é mais eficaz e menos custosa. Este trabalho busca discutir a relevância da teoria da legitimidade e da justeza procedimental para o debate atual das reformas da polícia no contexto brasileiro e apontar como as políticas públicas de segurança implementadas no país tem adotado estratégias baseadas no modelo dissuasório. Indicamos como essa agenda de pesquisa pode contribuir para a discussão a respeito das reformas das polícias no Brasil e na América Latina.
Eksplorasi dan Karakterisasi Tanaman Genjer (Limnocharis flava (L.) Buch) di Kabupaten Pangandaran Berdasarkan Karakter Morfologi dan Agronomi
Authors: Chaidir Liberty , Yuliani Kristi , Taufik Qurrohman Budy Frasetya 
Published: January 2017

Genjer merupakan tanaman yang tumbuh liar di area persawahan, rawa, atau sungai yang keberadaannya sering dianggap sebagai gulma. Tanaman genjer memiliki banyak manfaat, diantaranya sebagai bahan penyerap logam berat dalam tanah dan sebagai obat yang memiliki banyak kandungan gizi. Penelitian ini bertujuan untuk mengetahui variasi karakter morfologi dan karakter agronomi untuk mengetahui hubungan kekerabatan tanaman genjer antar daerah di Kabupaten Pangandaran. Penelitian dilaksanakan di Kabupaten Pangandaran pada Mei sampai Oktober 2015. Metode yang digunakan adalah metode eksplorasi purposive sampling pada 77 aksesi genjer yang diambil dari Kabupaten Pangandaran. Hasil penelitian menunjukkan terdapat keragaman fenotipik yang luas pada karakter morfologi ujung daun, warna batang, tekstur daun, warna daun, panjang lekukan bawah daun, warna kelopak bunga dan warna bunga. Karakter agronomi yang mempunyai keragaman yang luas ialah tinggi tanaman, jumlah batang per rumpun, panjang daun, lebar daun, jumlah daun, jumlah bunga dan diameter batang. Tanaman genjer di Kabupaten Pangandaran memiliki kekerabatan yang jauh dengan rentang jarak Euclidian 0,48 sampai 10,17. Aksesi yang memiliki hubungan kekerabatan paling jauh yaitu Ciakar (001) dengan jarak Euclidian 10,17, sedangkan yang memiliki hubungan kekerabatan paling dekat yaitu Cikalong (003) dan Cikalong (004) dengan jarak Euclidian 0,48. Genjer or Yellow velvetleaf is a plant that grows wild in lowland area, swamp or river which existence is considered as a weed. Genjer has a lot of benefits, such as material absorbent for heavy metals in the soil and medicine that has a lot of nutrition. This study aimed to determine the variety of morphological and agronomic characters of Genjer in Pangandaran Regency and to determine the genetic relationship of genjer between regions in Pangandaran. The research was conducted in the Pangandaran Regency on May to October 2015. The method used purposive sampling exploration method in 77 accession genjer collected from Pangandaran Regency. The results showed there were extensively phenotypic variation in tip of leaf, stem color, leaf texture, leaf color, length curve of bottom leaf, petal color and flower color. While agronomic characters for plant height, stem amount, leaf length, leaf width, leaf amount, flower amount and diameter of the stem had wide variation. Relationship between genjer in Pangandaran Regency had Euclidean distance with a range of 0.48 to 10.17. The accession which had the farthest distance was Ciakar (001) with Euclidean distance of 10.17, while those with the closest relationship were Cikalong (003) and Cikalong (004) with Euclidean distance of 0.48.
Neonatal outcome in meconium stained amniotic fluid: a hospital based study
Authors: Singh Gurmeet , Singh Onkar , Thapar Karuna 
Published: January 2017

Background: Amniotic fluid surrounds the baby in utero and provides a protective and low resistance environment and acts as a cushion for the baby. It is secreted by amniotic membranes, foetal skin and fetal urine. The objectives of this study was to identify the incidence of meconium stained amniotic fluid, perinatal outcome and the risks during pregnancy leading to in utero passage of meconium.Methods: A prospective study conducted in Sri Guru Ram Das University, Amritsar, between 1st December 2014 to 1st June 2016. All live births with meconim stained amniotic fluid without congenital malformation, twin or multiple organ dysfunction were taken as subjects of this study. Maternal obstetric history and risk factors were asked and foetal parameters including gestational age, fetal presentation, mode of delivery, birth weight, sex, Apgar score, age at onset of respiratory distress, treatment and outcome were observed.Results: Out of 1121 admissions in NICU, 12% of inborn and 9.6% of outborn were with MSAF, out of which 34% developed MAS. Majority of neonates were observed to be males (73.6%), term neonates (67.2%), weight 2.5-3.5 kg (76.9%) with mean weight being 2.701 kg±0.558 kg and 16% mortality including 9 inborn and 11 outborn neonates. Mean age at onset of respiratory distress was 18.43 minutes±11.52 minutes. Neonatal outcome was significantly related to weight, APGAR score at 5 mins, and development of complications like MAS, hypoxic ischemic encephalopathy, necrotizing enterocolitis, acute renal failure and severe thrombocytopenia. Culture proven septicaemia was seen in 21.6% cases. Mean duration of stay in NICU was 6.48 days±0.54 days.Conclusions: MSAF has significant effect on perinatal outcome and close observation is required to prevent and treat complications thus reducing mortality.