bluuebunny/crossref_metadata_2025_split huggingface dataset:
Houd de vertegenwoordiger kort aangelijnd
Authors: Spanjaard J.H.M. 
Published: June 2017

Houd de vertegenwoordiger kort aangelijnd
Op 3 februari 2017 wees de Hoge Raad twee arresten over de schijn van volmachtverlening. In deze arresten stond de vraag centraal wanneer van toerekening sprake kan zijn. Het antwoord: als feiten en omstandigheden aanwezig zijn die aan de achterman kunnen worden toegerekend. Deze arresten worden besproken tegen hun dogmatische achtergrond en in vergelijking met de aansprakelijkheid voor bodes en met het geval waarin is onderhandeld met een voorbehoud.
Comparative Study Between Zero-Order Spectra-Processing and Ratio Spectra-Manipulating Methods Applied for the Determination of Isoxsuprine Hydrochloride in the Presence of Its Oxidative Degradation Product
Authors: Attia Khalid A M , El-Abassawi Nasr M A , Said Ragab A M , El-Olemy Ahmed , Ramzy Sherif 
Published: June 2017

Abstract
Four accurate, precise, and validated stability-indicating spectrophotometric methods handling either zero-order spectra or ratio spectra have been developed and compared for the analysis of isoxsuprine hydrochloride (ISX) in the presence of its oxidative degradation product. The first two methods processed zero-order spectra, namely graphical absorbance ratio or Q-Analysis and area under the curve, whereas the third and fourth methods manipulated ratio spectra, namely the ratio difference spectrophotometric method and derivative ratio. The proposed methods showed good linearity in the range of 2–23 µg/mL. The methods were tested for specificity using laboratory-prepared mixtures containing the drug and its degradation product. The proposed methods were applied for the determination of ISX in Vascular tablets and the obtained results were acceptable, with small percentage RSD values. The validity of the proposed procedures was further assessed by applying the standard addition technique, which showed no interference from excipients. The obtained results were statistically compared with those obtained by the reported method, showing no significant differences when t- and F-tests were applied.
Determination of Several Element Levels in Hardaliye Beverages Using Flame Atomic Absorption Spectrometry After Ultrasound-Probe Extraction
Authors: Bakircioglu Dilek , Topraksever Nukte , Kurtulus Yasemin Bakircioglu 
Published: June 2017

Abstract
In the present study, concentrations of calcium (Ca), copper (Cu), magnesium (Mg), manganese (Mn), sodium (Na), and zinc (Zn) in hardaliye samples produced in Turkey were determined by flame atomic absorption spectrometry after ultrasound probe extraction (UPE), microwave-assisted extraction (MAE), and wet extraction procedures. At present, there is limited work in the literature on UPE for the determination of trace elements in beverage samples. Our single-correlation analysis showed that the elements studied with the UPE method in hardaliye were strongly correlated with the MAE procedure. The parameters affecting the UPE experimental conditions—such as ultrasound amplitude, sonication time, sample amount, extractant type, and volume—were studied. Optimal experimental conditions for the extraction of the metals with the UPE procedure were as follows: 2 min of sonication; 30% amplitude; 3 mL sample volume;5% HNO3 extraction solution; and 1 mL extractant volume for Ca, Cu, Mg, Mn, Na, and Zn in thehardaliye samples. The results in the hardaliye samples in minimum–maximum mg/L with the UPE procedure were 33–63 for Ca, 0.10–0.27 forCu, 3.9–14.4 for Mg, 1.0–3.2 for Mn,32–58 for Na, and 0.39–1.1 for Zn. LODs were 0.0032, 0.012, 0.013, 0.009, 0.011, and 0.008 mg/L for Ca, Cu, Mg, Mn, Na, and Zn, respectively. The accuracy of the method was verified with a recovery test (in which recoveries between 95 and 110% wereobserved) and application to a NIST 1643e certified sample (trace elements in water). The UPE procedure was found to be fast, accurate, and simple, with fewer contaminants and lower concentrated reagent consumption in comparison with conventional extraction procedures.
Microlecture stylistique de Claude Simon
Authors: Zemmour David 
Published: June 2017

Les romans de Claude Simon revêtent une dimension fondamentalement holistique en vertu de laquelle toutes les composantes de l’écriture (thématiques, mais aussi énonciatives, syntaxiques ou encore figurales) entrent en résonance les unes avec les autres pour oeuvrer à l’expression d’une certaine vision du monde hantée par une émotion particulière. Le phénomène est ici illustré à partir de l’étude stylistique d’une page de La bataille de Pharsale (1969) en vue de démontrer, s’agissant de ce roman, que ces résonances entretiennent une tension récurrente entre identité et altérité et permettent au « je » de se dire en creux sur le mode du contournement, dont les manifestations en myriades de réverbérations protéiformes sont constitutives d’une écriture de l’obsession.
Lire Claude Simon lisant Proust
Authors: Genin Christine 
Published: June 2017

Comme Roland Barthes, Claude Simon aurait pu écrire « Proust, c’est ce qui me vient », tant Marcel Proust est omniprésent dans l’ensemble de son oeuvre, se cache dans la plupart de ses recoins, les plus lumineux comme les plus sombres. Qu’il le prenne comme modèle de ses propres expérimentations dans ses entretiens, puise dans son oeuvre des leçons de composition, partage avec lui le goût des métaphores, déstructure et parodie ses analyses psychologiques, en fasse un personnage de ses romans, le regarde travailler et relire ses épreuves ou décrive avec lyrisme ses phrases « d’une mortelle somptuosité », il semble le lire et le relire sans fin. En suivant quelques fils de lecture, qui parfois s’entremêlent — la mémoire, les haies d’aubépines, les rats, la peinture ou les poissons cathédrales —, cet article tente de lire Simon lisant Proust, de lire Proust écrit par Simon, de lire Simon en prenant par Proust, de (re)lire Proust à travers Simon, etc.
Modèles littéraires de l’art contemporain : Marcelline Delbecq lectrice de Claude Simon ?
Authors: Mougin Pascal 
Published: June 2017

L’influence de Claude Simon sur les artistes contemporains est moins perceptible que celle, entre autres, de Beckett, Duras ou Robbe-Grillet. L’absence de relations directes, malgré les occasions de rencontre, entre Simon lui-même et les artistes des dernières avant-gardes du xxe siècle, explique sans doute en partie le phénomène. Reste que des échos simoniens se font entendre dans le travail de l’artiste française Marcelline Delbecq (en particulier Blackout, 2011). Les similitudes stylistiques (métalepse, flottement énonciatif et ambivalence sémiotique) et thématiques (autour de la production des simulacres) signent l’air de famille derrière l’inversion des enjeux et des effets : chez le romancier, une écriture du monde tel qu’il est, tournée vers l’énigme de la présence et de la représentation ; chez Delbecq, un dispositif de projection fictionnelle, pariant sur l’absence et la ténuité suggestive. Si le sous-texte simonien n’est pas revendiqué par l’artiste, il n’en est pas moins significatif d’une filiation culturelle dont les relais sont à rechercher, d’une manière large et diffuse, dans la réception du Nouveau roman par le minimalisme américain des années 1960, et, d’une manière plus étroite et spécifique, dans une double lecture de Merleau-Ponty, ascendant commun expliquant aussi bien la proximité que les différences entre Delbecq et Simon.
La surface et son envers. Poésie et poétique chez Robert Melançon
Authors: Dumont François 
Published: June 2017

Depuis 1978, Robert Melançon a fait paraître de nombreux recueils de poèmes qui constituent une oeuvre cohérente associant l’écriture de la poésie au développement d’une poétique. Celle-ci prend la forme de fragments d’« art poétique » intégrés aux poèmes et d’un certain nombre d’essais. Axée sur l’observation, la poésie de Melançon s’attache d’abord, dans les premiers recueils, à définir ses propres limites, en mettant en oeuvre une critique de la subjectivité, dont la conception est ensuite renouvelée par la pratique du renga, en collaboration avec Jacques Brault. Dans la suite de l’oeuvre, les formes traditionnelles du vers régulier, puis du sonnet, prendront valeur de médiations fondamentales, au même titre que la référence à la peinture et la recherche des fondements de nombreuses oeuvres poétiques, de provenances et d’époques très diverses. Au fil du développement de l’oeuvre, la négativité, tout en restant présente, accorde de plus en plus de place à l’acceptation des limites de la poésie.
Diversity analysis of gut microbiota in osteoporosis and osteopenia patients
Authors: Wang Jihan , Wang Yangyang , Gao Wenjie , Wang Biao , Zhao Heping , Zeng Yuhong , Ji Yanhong , Hao Dingjun 
Published: June 2017

Some evidence suggests that bone health can be regulated by gut microbiota. To better understand this, we performed 16S ribosomal RNA sequencing to analyze the intestinal microbial diversity in primary osteoporosis (OP) patients, osteopenia (ON) patients and normal controls (NC). We observed an inverse correlation between the number of bacterial taxa and the value of bone mineral density. The diversity estimators in the OP and ON groups were increased compared with those in the NC group. Beta diversity analyses based on hierarchical clustering and principal coordinate analysis (PCoA) could discriminate the NC samples from OP and ON samples. Firmicutes, Bacteroidetes, Proteobacteria and Actinobacteria constituted the four dominant phyla in all samples. Proportion of Firmicutes was significantly higher and Bacteroidetes was significantly lower in OP samples than that in NC samples (p < 0.05), Gemmatimonadetes and Chloroflexi were significantly different between OP and NC group as well as between ON and NC group (p < 0.01). A total of 21 genera with proportions above 1% were detected and Bacteroides accounted for the largest proportion in all samples. The Blautia, Parabacteroides and Ruminococcaceae genera differed significantly between the OP and NC group (p < 0.05). Linear discriminant analysis (LDA) results showed one phylum community and seven phylum communities were enriched in ON and OP, respectively. Thirty-five genus communities, five genus communities and two genus communities were enriched in OP, ON and NC, respectively. The results of this study indicate that gut microbiota may be a critical factor in osteoporosis development, which can further help us search for novel biomarkers of gut microbiota in OP and understand the interaction between gut microbiota and bone health.
Annual Wellness Visits and Early Dementia Diagnosis Among Medicare Beneficiaries
Authors: Tzeng Huey-Ming , Raji Mukaila A. , Shan Yong , Cram Peter , Kuo Yong-Fang 
Published: October 2024

ImportanceEarly recognition of cognitive impairment is key to optimal dementia care. No previous research has examined the probability of developing mild cognitive impairment (MCI) or Alzheimer disease and related dementias (ADRD) at 5-year follow-up among older adult Medicare beneficiaries by receipt of an annual wellness visit (AWV).ObjectiveTo assess the association of incident AWV with the first ADRD or MCI diagnosis among older adults with Medicare fee-for-service benefits.Design, Setting, and ParticipantsThis retrospective population-based cohort study used 100% Texas fee-for-service Medicare data from 2015 to 2022. Participants comprised 549 516 community-dwelling Medicare beneficiaries aged 68 years or older in 2018, with complete Medicare fee-for-service Parts A and B and no Medicare Advantage plan enrollment for 2015 to 2018.ExposureMedicare AWVs.Main Outcomes and MeasuresThe first MCI or ADRD diagnosis (reported as MCI or ADRD diagnosis, MCI diagnosis, and ADRD diagnosis) from the AWV index date in 2018 through December 31, 2022.ResultsIn this cohort study of 549 516 Medicare beneficiaries with no diagnosis of MCI or ADRD in 2015 to 2017 (mean [SD] age, 76.7 [6.6] years; 289 932 women [52.8%]), 66 433 (12.1%) had an incident AWV in 2018. Annual wellness visit recipients were more likely than those who did not receive an AWV to be female, to be non-Hispanic White (followed by Hispanic, non-Hispanic Black, and other), to have more education, to reside in a metropolitan area, to have more comorbidities, and to have a primary care professional in the 12 months before the AWV index date. After propensity score matching, AWV receipt was associated with a 21% increase in MCI diagnosis (hazard ratio, 1.21 [95% CI, 1.16-1.27]) and a 4% increase in ADRD diagnosis (hazard ratio, 1.04 [95% CI, 1.02-1.06]). The increase in MCI diagnosis associated with AWV was larger when the AWV was censored or treated as a time-dependent covariate in the follow-up period.Conclusions and RelevanceThese findings indicate that AWV recipients had a timelier first MCI diagnosis than those who did not receive an AWV, but first ADRD diagnosis differed little. This study suggests that the Medicare AWV health policy may increase MCI identification, prompting more specialized care.
Risk for Suicide Attempts Assessed Using the Patient Health Questionnaire–9 Modified for Teens
Authors: Tsui Fuchiang , Ruiz Victor M. , Ryan Neal D. , Shi Lingyun , Melhem Nadine M. , Young Jami F. , Davis Molly , Gibbons Robert , Brent David A. 
Published: October 2024

ImportanceSuicide is a leading cause of death in US youths.ObjectiveTo assess whether screening with supplemental items 10 to 13 on the Patient Health Questionnaire–9 modified for teens (PHQ-9M) improves prediction of youth suicide attempts beyond the information provided by the first 9 items alone (the PHQ-9).Design, Setting, and ParticipantsThis retrospective cohort study used a retrospective cohort of adolescents aged 12 to 17 years who were screened for depression in outpatient facilities within a pediatric health care system between January 1, 2016, and December 31, 2022, with up to 1 year of follow-up to assess the occurrence of suicidal behavior. Follow-up was completed on December 31, 2023.ExposureScreening with the PHQ-9M.Main Outcomes and MeasuresThis study developed and compared prediction using 3 Cox proportional hazards regression models (CR-9, CR-13, and CR-3) of subsequent suicide attempts, determined by the hospital’s electronic health records up to 1 year following the last PHQ-9M screening. The CR-9 model used the PHQ-9 and the CR-13 model used all 13 items of PHQ-9M. The CR-3 model used the 3 most impactful variables selected from the 13 PHQ-9M items and PHQ-9 total score. All models were evaluated across 4 prediction horizons (30, 90, 180, and 365 days) following PHQ-9M screenings. Evaluation metrics were the area under the receiver operating characteristic curve (AUROC) and the area under the precision recall curve (AUPRC).ResultsOf 130 028 outpatients (65 520 [50.4%] male) with 272 402 PHQ-9M screenings, 549 (0.4%) had subsequent suicide attempts within 1 year following the PHQ-9M screening. The AUROC of the CR-9 model in the 365-day horizon was 0.77 (95% CI, 0.75-0.79); of the CR-13 model, 0.80 (95% CI, 0.78-0.82); and of the CR-3 model, 0.79 (95% CI, 0.76-0.81); the AUPRC of the CR-9 model was 0.02 (95% CI, 0.02-0.03); of the CR-13 model, 0.03 (95% CI, 0.02-0.03); and of the CR-3 model, 0.02 (95% CI, 0.02-0.03). The 3 most impactful items using adjusted hazard ratios were supplemental item 13 (lifetime suicide attempts; 3.06 [95% CI, 2.47-3.80]), supplemental item 10 (depressed mood severity in the past year; 2.99 [95% CI, 2.32-3.86]), and supplemental item 12 (serious suicidal ideation in the past month; 1.63 [95% CI, 1.25-2.12]). All of the models achieved higher AUROCs as prediction horizons shortened.Conclusions and RelevanceIn this cohort study of adolescent PHQ-9M screenings, the supplemental items on PHQ-9M screening improved prediction of youth suicide attempts compared with screening using the PHQ-9 across all prediction horizons, suggesting that PHQ-9M screening should be considered during outpatient visits to improve prediction of suicide attempts.
Utility of automated CT perfusion software in acute ischemic stroke with large and medium vessel occlusion
Authors: Ashayeri Ahmadabad Rezan , Tran Kim H. , Zhang Yiran , Kate Mahesh P. , Mishra Sachin , Buck Brian H. , Khan Khurshid A. , Rempel Jeremy , Albers Gregory W. , Shuaib Ashfaq 
Published: October 2024

AbstractBackgroundEarly diagnosis of large vessel occlusion (LVO) in acute stroke often requires CT angiography (CTA). Automated CT perfusion (CTP) software, which identifies blood flow abnormalities, enhances LVO diagnosis and patient selection for endovascular thrombectomy (EVT). This study evaluates the sensitivity of automated CTP images in detecting perfusion abnormalities in patients with acute ischemic stroke (AIS) and LVO or medium vessel occlusion (MeVO), compared to CTA.MethodsWe screened acute ischemic stroke patients presenting within 24 h who underwent CT, CTA, and CTP as per institutional protocol. RAPID AI software processed CTP images, while neuroradiologists reviewed CTA for intracranial arterial occlusions. Sensitivity, specificity, and accuracy of automated CTP maps in detecting occlusions were assessed.ResultsOf 790 screened patients, 31 were excluded due to lack of RAPID CTP data or poor‐quality scans, leaving 759 for analysis. The median age was 71 years (IQR: 61–81), with 47% female. Among them, 678 had AIS, and 81 had AIS ruled out. CTA identified arterial occlusion in 562 patients (74%), with corresponding CTP abnormalities in 537 patients (Tmax > 6 sec). In the 197 without occlusion, CTP was negative in 161. Automated CTP maps had a sensitivity of 95.55% (CI 95: 93.50–97.10%), specificity of 81.73% (CI 95: 75.61–86.86%), negative predictive value of 98.22% (CI 95: 97.39–98.79%), positive predictive value of 63.54% (CI 95: 56.46–70.09%), and overall accuracy of 85.18% (CI 95: 82.45–87.64%).ConclusionsAutomated CTP maps demonstrated high sensitivity and negative predictive value for LVOs and MeVOs, suggesting their usefulness as a rapid diagnostic tool, especially in settings without expert neuroradiologists.
Low‐Temperature Sodium–Sulfur Batteries Enabled by Ionic Liquid in Localized High Concentration Electrolytes
Authors: Guo Dong , Wang Jiaao , Cui Zehao , Shi Zixiong , Henkelman Graeme , Alshareef Husam N. , Manthiram Arumugam 
Published: October 2024

AbstractLow ionic migration and compromised interfacial stability pose challenges for low‐temperature batteries. In this work, we discovered that even with the state‐of‐the‐art localized high‐concentration electrolytes (LHCEs), uncontrolled Na electrodeposition occurs with a huge overpotential of >1.2 V at −20 °C, leading to cell failure within tens of hours. To address this, we introduce a new electrolyte category that incorporates an ionic liquid as a key solvation species. Diverging from traditional LHCEs, the IL‐tailored LHCE facilitates an anion–solvent‐molecules exchange within the solvation sheath between Na+ and organic cations at low temperatures. This behavior reduces solvation cluster size and strengthens Na+–anion coordination, which proves instrumental in enabling fast ionic dynamics in both the bulk liquid and at the interface. Therefore, durable Na electrodeposition and shuttle‐free, 0.5 Ah sodium–sulfur pouch cells are achieved at −20 °C, for the first time, surpassing the limitations of typical LHCEs. This tailoring strategy opens a new design direction for advanced batteries operating in fast‐charge and wide‐temperature scenarios.
Bidirectional Temperature‐Responsive Thermochromic Hydrogels With Adjustable Light Transmission Interval for Smart Windows
Authors: Wang Wenyi , Wang Kai , Cheng Yan , Wu Che , Wu Ruizi , Huang Jianying , Lai Yuekun 
Published: October 2024

AbstractThermochromic smart windows have been widely developed for solar regulation to save building energy. However, most current smart windows still exhibit a single responsiveness to a specific temperature, which is not conducive to daytime energy saving or nighttime privacy protection. Herein, a low‐temperature response is achieved by pre‐initiation of the monomer acrylamide (AAm) and acrylic acid (AA) in the synthesis of P(AAm‐co‐AA). Then, N‐isopropyl acrylamide and AAm are introduced into P(AAm‐co‐AA) to form a pre‐polymerized precursor solution. The liquid precursor solution can be encapsulated within two quartz glasses and synthesized in situ to prepare smart windows, which exhibit a high visible light transmittance of 84.4%, excellent solar modulation of 69.5%, and bidirectional temperature responsiveness (cold and hot). In addition, the upper critical solution temperature and the lower critical solution temperature of the hydrogel and the light transmission interval between the two temperatures can be flexibly adjusted to adapt to different climates and individual user needs. The designed smart window maintains a high light transmission within the human body's comfort temperature range. The bidirectional temperature response window achieves the dual functions of energy saving and privacy protection, making it an ideal smart window candidate with good prospects for practical applications.
Design and Improvement of Bone Adhesive in response to Clinical Needs
Authors: Liu Chenyu , Sha Dongyong , Zhao Lingfei , Zhou Chuanwei , Sun Lili , Liu Changsheng , Yuan Yuan 
Published: October 2024

AbstractFracture represents one of the most common diagnoses in contemporary medical practice, with the majority of cases traditionally addressed through metallic device fixation. However, this approach is marred by several drawbacks, including prolonged operative durations, considerable expenses, suboptimal applicability to comminuted fractures, increased infection risks, and the inevitable requirement for secondary surgery. The inherent advantages of bone adhesives in these fields have garnered the attention of orthopedic surgeons, who have commenced utilizing biocompatible and biodegradable bone adhesives to bond and stabilize bone fragments. Regrettably, the current bone adhesives generally exhibit insufficient adhesive strength in vivo environments, and it is desirable for them to possess effective osteogenesis to facilitate fracture healing. Consequently, aligning bone adhesives with practical clinical demands remains a significant hurdle, which has catalyzed a surge in research endeavors. Within this review, the conceptual framework, characteristics, and design ideas of bone adhesives based on clinical needs are delineated. Recent advancements in this domain, specifically focusing on the enhancement of two pivotal characteristics—adhesive strength and osteogenic potential are also reviewed. Finally, a prospective analysis of the future advancements in bone adhesives, offering new insights into solutions for diverse clinical problems is presented.