bluuebunny/crossref_metadata_2025_split huggingface dataset:
KEBENARAN HEGEMONIK AGAMA
Authors: Tajrid Amir 
Published: May 2017

<p class="IIABSBARU">Anarchic violence against jamaah Ahmadiyah and “Aliansi Ke­bangsa­­­­­an untuk Kebebasan Beragama dan Berkeyakinan (AKKBB)” by Front Pembela Islam (FPI) constitutes a form of truth claim among religious groups in religious society. The religious inter­pretation which formerly opened now reduced to become the closed interpretation. The formerly is the substantive interpretation now become the hegemonic interpretation. This is one of the greatest theological challenge facing by religious community. This article will show the patterns of attitude and idea among religious comminity members which stimulate hegemonic truth claim in order to find out the friendly, egalitarian, and tolerant forms of religions, so the hegemonic truth claim of the religion should be avoided.</p><p class="IKa-ABSTRAK">***</p>Kekerasan anarkis yang ditujukan kepada jamaah Ahmadiyah dan “Aliansi Kebangsaan untuk Kebebasan Beragama dan Berkeyakinan (AKKBB)” oleh Front Pembela Islam (FBI) merupakan bentuk klaim kebenaran di antara kelompok-kelompok agama di dalam masyarakat agama. Interpretasi agama yang s­e­belumnya terbuka kini menjadi tertutup. Sebelumnya interpretasinya bersifat substantif namun kini menjadi hegemonik. Inilah salah satu tantangan terbesar yang dihadapi oleh komunitas agama saat ini. Artikel ini akan membahas pla sikap dan ide di kalangan anggota komunitas yang mencetuskan klaim kebenaran yang hegemonik dalam rangka untuk menemukan bentuk keberagamaan yang bersahabat, egalitarian, dan toleran sehingga klaim kebenaran hegemonik agama dapat dihindari.
ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF SELECTED PLANTS USED BY POPULATIONS FROM JURUENA VALLEY, LEGAL AMAZON, BRAZIL
Authors: Silva Larissa Irene Da , Karuppusamy Arunachalam , Miyajima Fabio , Violante Ivana Maria Povoa , Bieski Isanete Geraldini Costa , Balogun Sikiru Olaitan , Martins Domingos Tabajara De Oliveira 
Published: May 2017

Objective: The purpose of this study was to evaluate selected Brazilian plants from Juruena valley region of Mato Grosso, for their in vitro antimicrobial and antioxidant activities.Methods: The powder obtained from different parts of the twenty-six (26) plants were macerated in hydroethanolic solution to obtain the extracts. The hydroethanolic extracts were tested for their in vitro antimicrobial activity by determining the MIC using broth microdilution. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical, ferric reducing antioxidant power (FRAP) and nitric oxide (NO) methods were used for the determination of antioxidant activities. Correlation between classes of secondary metabolites and antioxidant activity was assessed.Results: Phanera glabra extract (HEPg) showed broad antibacterial spectrum, presenting the best activity against Klebsiella pneumoniae. Hevea microphylla extract (HEHm) presented a narrow spectrum of antibacterial activity with strong effect against Shigella flexneri. The only plant with broad spectrum antifungal activity was Bertholletia excelsa (HEBe), with moderate activity against strains of Aspergillus and Candida. The following extracts were prominent regarding their activities in the DPPH and FRAP assays-HEBe, Cariniana rubra (HECr) and in the FRAP assay alone, Cedrela odorata (HECo) and HEPg. None of the extracts was active in the NO assay. A significant association was observed between DPPH activity and the total phenolic contents.Conclusion: Our results justified the use of some of the investigated plants in the Brazilian ethnomedicine. The antibacterial activities of these plants are bacteriostatic in nature. These findings support that a number of investigated plants could be a valuable source of new antioxidant and antimicrobial compounds that can potentially deliver novel mechanisms of actions.However, further studies are required.
V. NEGUNDO, L. CAMARA AND B. VARIEGATA PLANTS LEAF EXTRACT EXHIBIT CONSIDERABLE IN VITRO ANTIOXIDANT AND ANTICANCER ACTIVITIES
Authors: Badgujar Nutan , Mistry Kinnari , Patel Jagdish 
Published: May 2017

Objective: The study was planned to investigate antioxidant and anticancer activities with the preliminary phytochemical analysis of methanolic extracts of Vitex negundo (V. negundo), Lantana camara (L. camara) and Bauhania variegata (B. variegata) plants leaf extracts.Methods: Phytochemical evaluation was performed for all the extracts, as per the standard methods. In vitro antioxidant activities were performed by using DPPH (2,2-Diphenyl-1-Picrylhydrazyl), ABTS (2, 2'-Azino-Bis-3-Ethylbenzothiazoline-6-Sulfonic Acid) and FRAP (Ferric reducing antioxidant power assay) method and compared with standard antioxidants. The anticancer activity of plant extract was assessed using MTT colorimetric assay.Results: The study of preliminary phytochemical proved the existence of alkaloids, flavonoids and phenolic types of phytochemicals in high amount. Methanolic extract of L. camara shows minimum IC50 value for DPPH assay (48.75±2.34 µg/ml) and FRAP assay (274.66±3.65 µg/ml). In ABTS assay B. variegata extract exhibit minimum IC50 value (60.48±3.01 µg/ml). Lower the IC50 value of extract, higher the effectiveness of the plant. Methanolic extract of all plants methanolic extracts showed anticancer activity against SH-SY-5Y cells (human neuroblastoma cell) but V. negundo was more effective against SH-SY-5Y cells with IC50 value (209 µg/ml) compared to remaining extracts.Conclusion: The current finding accomplished the in vitro activities, so that plant could be a superior source of antioxidant and anticancer drugs. But further in vivo assessment was needed before adding it into the pharma industry.
Consumo de alcohol en estudiantes universitarios colombianos
Authors: Betancourth Zambrano Sonia , Tacán Bastidas Lised Evelin , Córdoba Paz Edwin Giovanny 
Published: May 2017

Introducción: El consumo de alcohol se concibe como una problemática de salud pública, dada la significativa prevalencia de consumo y las consecuencias negativas, se precisa contribuir a la prevención desde la identificación de poblaciones en riesgo como la universitaria y los factores que influyen en el desarrollo del consumo. Objetivo: Identificar y analizar los factores asociados al consumo de alcohol en estudiantes universitarios del sur-occidente colombiano. Materiales y métodos: Estudio descriptivo–transversal con una muestra de 849 estudiantes universitarios, obtenida por muestreo aleatorio estratificado. Para la recolección de datos cuantitativos se aplicó un cuestionario para caracterizar el consumo de alcohol y los factores sociodemográficos. El análisis de la información incluyó estadísticos descriptivos para prevalencia, patrón de consumo y policonsumo, así mismo se calculó la relación entre las variables a través de la prueba Chi-cuadrado. Resultados: Se encontró una prevalencia de consumo de alcohol de 97,5%, la mayoría de estudiantes reportan consumir alcohol con su grupo de amigos (76%), seguido de la familia (24,9%). La frecuencia de consumo de alcohol se da principalmente cada mes (25,8%) y cada quince días (18,8%). Además, se encontró asociaciones entre sexo y la frecuencia de consumo de alcohol (p=000) y el número de tipo de bebidas alcohólicas (p= 000), donde son los hombres quienes mayor consumen y quienes principalmente mezclan diferentes tipos de bebidas. Conclusiones: Los niveles de consumo de alcohol se mantienen con el tiempo y es necesario que las universidades se preocupen por una educación integral que permita disminuir el consumo de alcohol.
Natural product as a source of prodrug
Authors: Padmavathy Jagannathan , Devarajan Saravanan 
Published: May 2017

The natural products are the chemical constituents that are generated from the living organism. The natural products are isolated from the plants, animals, and microorganisms which are used in drug design and drug discovery. Natural product is then modified by chemical synthesis as either total or semi-synthetic way. The natural products show various pharmacological activity which can be used for the treatment of a variety of diseases. Natural products could be regarded as a source of quantifiable and chemically pure known products and also natural products can be utilized as complex mixtures subjected to chemical variability. The present review article adds up the prodrugs from natural products as well as prodrugs developed from the natural products.
Utilizing Electronic Medical Records to Discover Changing Trends of Medical Behaviors Over Time
Authors: Yin Liangying , Huang Zhengxing , Dong Wei , He Chunhua , Duan Huilong 
Published: May 2017

SummaryObjectives: Medical behaviors are playing significant roles in the delivery of high quality and cost-effective health services. Timely discovery of changing frequencies of medical behaviors is beneficial for the improvement of health services. The main objective of this work is to discover the changing trends of medical behaviors over time.Methods: This study proposes a two-steps approach to detect essential changing patterns of medical behaviors from Electronic Medical Records (EMRs). In detail, a probabilistic topic model, i.e., Latent Dirichlet allocation (LDA), is firstly applied to disclose yearly treatment patterns in regard to the risk stratification of patients from a large volume of EMRs. After that, the changing trends by comparing essential/critical medical behaviors in a specific time period are detected and analyzed, including changes of significant patient features with their values, and changes of critical treatment interventions with their occurring time stamps.Results: We verify the effectiveness of the proposed approach on a clinical dataset containing 12,152 patient cases with a time range of 10 years. Totally, 135 patients features and 234 treatment interventions in three treatment patterns were selected to detect their changing trends. In particular, evolving trends of yearly occurring probabilities of the selected medical behaviors were categorized into six content changing patterns (i.e, 112 growing, 123 declining, 43 up-down, 16 down-up, 35 steady, and 40 jumping), using the proposed approach. Besides, changing trends of execution time of treatment interventions were classified into three occurring time changing patterns (i.e., 175 early-implemented, 50 steady-implemented and 9 delay-implemented).Conclusions: Experimental results show that our approach has an ability to utilize EMRs to discover essential evolving trends of medical behaviors, and thus provide significant potential to be further explored for health services redesign and improvement.
Intervenir en institution : préserver de la groupalité et restaurer de l’intermédiaire
Authors: Gaillard Georges 
Published: May 2017

Le champ de la mésinscription (soin, travail social, etc.) est massivement impacté par les mutations, et par le mouvement de désinstitutionnalisation, en cours. Il est aux prises avec deux sources principales de déliaison mortifère : celle que présentifient les usagers, d’une part, et celle qui découle des incidences des mutations sociales, des incessantes restructurations et des menaces qu’elles font peser sur les organisations institutionnelles, d’autre part. Celles-ci s’en trouvent grandement fragilisées et le travail de nouage en devient d’autant plus exigeant, car il requiert toujours plus d’énergie, face aux différents niveaux par où les liens sont déstabilisés, malmenés, détruits. Dans ce contexte, l’analyse de la pratique peut être pensée comme paradigmatique des pratiques de régulations, en tant qu’elle peuvent contribuer à faire tenir ensemble ce qui tend à se morceler au sein de la vie institutionnelle ; à préserver de la créativité et de l’investissement dans un univers où les marges de libertés (professionnelles) n’ont de cesse de se restreindre. Ces pratiques peuvent se donner pour visée de soutenir, voire de faire advenir, du groupe comme une instance suffisamment unifiante, participant en cela à la reconstruction des collectifs de travail et du « bien commun ».
La déliaison orchestrée par le thanatophore, une défense possible pour les institutions : l’objet de la relation
Authors: Barrer Laurence 
Published: May 2017

L’objectif de cet article est d’esquisser un positionnement institutionnel de défense lors de la convocation d’un « thanatophore » et d’apporter quelques éléments à la théorie déjà existante. Les concepts de thanatophore et de pervers narcissique sont les bases sur lesquelles cet article s’appuie pour en rendre compte. L’émergence de cette personnalité engendre une déliaison extrême conviant la mort physique aux portes des institutions mettant à mal l’existence des liens institutionnels et des alliances inconscientes du groupe. L’auteur développe l’hypothèse que la défense du groupe contre la déliaison et sa tentative de restructuration du lien s’organisent et se figurent autour d’objets de relation, et, que les conditions de l’émergence de mouvements pervers sont inhérentes à certaines institutions. Après avoir repris le modèle du thanatophore, l’articulation avec une expérience clinique dans une institution de soin psychique aboutira à mettre en perspective une défense institutionnelle possible face à ces processus pervers de déliaison.
Enjeux et actualité de l’étude de cas clinique de groupe dans la recherche contemporaine
Authors: Canet Géraldine , Falquet Christine , Lecourt Édith 
Published: May 2017

Ancrée dans une longue tradition, l’étude de cas est une modalité de recherche toujours actuelle et féconde, véritable « noyau vivant » entre pratique clinique et élaboration théorique. Nous constatons que la pratique clinique groupale référée à l’épistémologie psychanalytique, pourtant très largement pratiquée dans le quotidien des institutions mais d’une complexité difficile à restituer, fait peu l’objet de véritables études de cas. Deux cas nous paraissent princeps : Chronique d’un groupe de R. Kaës et D. Anzieu (1976) dans le champ du groupe, et l’étude de cas d’ Edward , dans Creative Music Therapy de Nordoff et Robbins (1977) pour la médiation artistique. À partir des fondements posés par ces deux cas et de données de la littérature, nous proposons de réfléchir aux enjeux de valorisation de la clinique groupale.
Modelos de volumen específicos y regionales para 12 especies forestales en el estado de Durango, México
Authors: Simental-Cano Bernardo , López-Sánchez Carlos A. , Wehenkel Christian , Vargas-Larreta Benedicto , Álvarez-González Juan G. , Corral-Rivas José J. 
Published: May 2017

Introducción: La estimación del volumen de árboles individuales es un aspecto relevante en la dendrometría y en la realización de inventarios forestales.Objetivo: Se evaluaron diferencias significativas en sistemas de ecuaciones aditivas para la estimación de volumen total de árboles individuales en nueve especies de Pinus (P. cooperi, P. durangensis, P. arizonica, P. leiophylla, P. teocote, P. engelmannii, P. lumholtzii, P. strobiformis y P. herrerae), y tres de Quercus (Q. sideroxyla, Q. durifolia y Q. rugosa), y entre unidades de manejo forestal regional (UMAFOR) cuando se trata de una misma especie.Materiales y métodos: Para evaluar si el sistema de ecuaciones difiere entre especies de un mismo género y entre las UMAFOR para una misma especie, se utilizaron dos análisis estadísticos complementarios basados en el ajuste de un sistema reducido y un sistema completo de ecuaciones: la prueba F asociada al método de la suma adicional de cuadrados no lineales y el análisis de significancia de los parámetros.Resultados y discusión: Para la mayoría de las especies estudiadas, los sistemas de ecuaciones son significativamente diferentes. Se reporta la necesidad de utilizar modelos regionales en 10 de las 12 especies, exceptuando a P. strobiformis y Q. rugosa.Conclusiones: Se recomienda el empleo de un modelo estatal para P. strobiformis y Q. rugosa.
Ecotono del límite superior del bosque de Pinus hartwegii Lindl.: estructura y límites altitudinales en el Nevado de Toluca, México
Authors: Alfaro-Ramírez Farid U. , Arredondo-Moreno José T. , Pérez-Suárez Marlín , Endara-Agramont Ángel R. 
Published: May 2017

Introducción: La complejidad del ecotono del límite superior del bosque de Pinus hartwegii puede funcionar como una barrera para la migración altitudinal.Objetivos: La estructura del bosque de P. hartwegii se caracterizó a través del ecotono de su límite superior en el Nevado de Toluca; además, se determinaron los posibles cambios en los límites altitudinales en los últimos 25 años.Materiales y métodos: Se determinaron la densidad arbórea, altura y diámetro normal de cada árbol, y la regeneración natural del bosque. Los límites altitudinales se determinaron mediante el método de la ventana móvil en imágenes de satélite de 1989 y 2014.Resultados y discusión: La densidad del arbolado se redujo entre 8 y 70 % en el gradiente altitudinal. Los límites altitudinales (3,980-4,130 m) no presentaron diferencias significativas (P = 0.07) entre los años evaluados. El ecotono es de forma difusa, regulado por limitaciones al crecimiento. Esto implica que el bosque modificará su distribución altitudinal en función de los cambios ambientales, de acuerdo con su amplitud ecológica y la rapidez con que puedan establecerse nuevos individuos a mayores altitudes.Conclusión: Es importante establecer monitoreos, a largo plazo, para saber si la especie es realmente capaz de migrar altitudinalmente como resultado del incremento de temperatura ambiental.
After Gnadenhütten: The Moravian Indian Mission in the Old Northwest, 1782–1812
Authors: Fisher Kyle 
Published: May 2017

ABSTRACT
This article examines the Moravian missions to Native Americans in the Old Northwest after the massacre of ninety-six Christian Indians at Gnadenhütten, Ohio, in 1782. It argues that the missions grew after the massacre despite the trauma of the event. Natives continued to find the Moravian culture centered on a theology of the suffering Savior a compelling reason to join the church, often in the context of famine, alcoholism, and displacement among Native communities. However, as seen in the White River mission in Indiana, nativist resistance movements presented an alternative to Moravian mission culture and prevented the missions from expanding westward. Missions in Ohio eventually declined because of pressures associated with rapid white settlement. While the Gnadenhütten massacre did not destroy the missions, it affected the way Indians interacted with Moravian Christianity.
Desenvolvimento do turismo baseado em elementos culturais
Authors: Camilo Irene , Bahl Miguel 
Published: May 2017

Neste artigo são feitas considerações relacionadas ao desenvolvimento da atividade turística de forma sustentável e sobre patrimônio histórico cultural, como parte relevante para o incremento do turismo e fonte de sustentabilidade para a atividade. Trata também da importância do planejamento para minimizar os efeitos negativos causados pelo turismo desordenado no meio ambiente natural e antrópico. Aborda a importância do planejamento para a sustentabilidade dos destinos turísticos, bem como a valorização do patrimônio como reforço da identidade de um determinado espaço geográfico. A metodologia utilizada foi a de pesquisa bibliográfica. A fundamentação embasou-se em autores que abordam os assuntos referentes ao planejamento sustentável, patrimônio histórico cultural e identidade.
Large‐Area, All‐Solid, and Flexible Electric Double Layer Capacitors Based on CNT Fiber Electrodes and Polymer Electrolytes
Authors: Senokos Evgeny , Reguero Víctor , Cabana Laura , Palma Jesús , Marcilla Rebeca , Vilatela Juan José 
Published: May 2017

This work presents a scalable method to produce robust all‐solid electric double layer capacitors (EDLCs), compatible with roll‐to‐roll processes and structural laminate composite fabrication. It consists in sandwiching and pressing an ionic liquid‐based polymer electrolyte membrane between two carbon nanotube (CNT) fiber sheet electrodes at room temperature, and laminating with ordinary plastic film. This fabrication method is demonstrated by assembling large‐area devices of up to 100 cm2 with electrodes fabricated in‐house, as well as with commercial CNT fiber sheets. Freestanding flexible devices operating at 3.5 V exhibit 28 F g−1 of specific capacitance, 11.4 W h kg−1 of energy density, and 46 kW kg−1 of power density. These values are nearly identical to control samples with pure ionic liquid. The solid EDLCs could be repeatedly bent and folded 180° without degradation of their properties, with a reversible 25% increase in energy density in the bent state. Devices produced using CNT fiber electrodes with a higher degree of orientation and therefore better mechanical properties show similar electrochemical properties combined with composite specific strength and modulus of 39 and 577 MPa SG−1 for a fiber mass fraction of 11 wt%, similar to a structural thermoplastic and with higher specific strength than copper.
Synthesis, Conformational Studies and Biological Profiles of Tetrahydrofuran Amino‐Acid‐Containing Cationic Antitubercular Peptides
Authors: Pal Sudip , Ghosh Uttam , Singh Gajendra , Alam Faiyaz , Singh Shyam , Chopra Sidharth , Sinha Sudhir , Ampapathi Ravi Sankar , Chakraborty Tushar Kanti 
Published: May 2017

AbstractLinear cationic tetra‐ and octapeptides containing a tetrahydrofuran amino acid were synthesised, a conformational analysis performed, and their structure–activity relationships explored by evaluating their antibacterial, antitubercular and cytotoxic properties. Only the octapeptides showed activities, which was weak to moderate against Gram‐positive and Gram‐negative bacteria for only two peptides, but was very significant against Mycobacterium tuberculosis, and peptides were devoid of toxicity towards mammalian Vero cells. N‐Terminus‐deprotected esters showed the best results with excellent selectivity for M. tuberculosis and these peptides promise to be potential leads.
Chromatin Regulates Genome Targeting with Cisplatin
Authors: Zacharioudakis Emmanouil , Agarwal Poonam , Bartoli Alexandra , Abell Nathan , Kunalingam Lavaniya , Bergoglio Valérie , Xhemalce Blerta , Miller Kyle M. , Rodriguez Raphaël 
Published: May 2017

AbstractCisplatin derivatives can form various types of DNA lesions (DNA‐Pt) and trigger pleiotropic DNA damage responses. Here, we report a strategy to visualize DNA‐Pt with high resolution, taking advantage of a novel azide‐containing derivative of cisplatin we named APPA, a cellular pre‐extraction protocol and the labeling of DNA‐Pt by means of click chemistry in cells. Our investigation revealed that pretreating cells with the histone deacetylase (HDAC) inhibitor SAHA led to detectable clusters of DNA‐Pt that colocalized with the ubiquitin ligase RAD18 and the replication protein PCNA. Consistent with activation of translesion synthesis (TLS) under these conditions, SAHA and cisplatin cotreatment promoted focal accumulation of the low‐fidelity polymerase Polη that also colocalized with PCNA. Remarkably, these cotreatments synergistically triggered mono‐ubiquitination of PCNA and apoptosis in a RAD18‐dependent manner. Our data provide evidence for a role of chromatin in regulating genome targeting with cisplatin derivatives and associated cellular responses.
Total Synthesis of a Dimeric Thymol Derivative Isolated from Arnica sachalinensis
Authors: De Silvestro Irene , Drew Samuel L. , Nichol Gary S. , Duarte Fernanda , Lawrence Andrew L. 
Published: May 2017

AbstractThe total synthesis of a dimeric thymol derivative (thymarnicol) isolated from Arnica sachalinensis was accomplished in 6 steps. A key biomimetic Diels–Alder dimerization was found to occur at ambient temperature and the final oxidative cyclization occurs when the substrate is exposed to air and visible light. These results indicate that this natural product is likely the result of spontaneous (non‐enzyme‐mediated) reactivity.