bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Algorithm for Multiphase-Fluid Characterization for Solvent Injection
Authors: Kumar Ashutosh , Okuno Ryosuke 
Published: April 2016

SummaryCompositional simulation of solvent injection requires reliable characterization of reservoir fluids by use of an equation of state (EOS). Under the uncertainty associated with nonidentifiable components, reservoir fluids are conventionally characterized in the absence of universal methodology. This is true even for relatively simple fluids involving only the gaseous (V) and oleic (L1) phases. No systematic method has been presented for characterization of more-complex fluids, exhibiting three hydrocarbon phases: the V, L1, and solvent-rich-liquid (L2) phases.This paper presents a new algorithm for systematic characterization of multiphase behavior for solvent-injection simulation. The reliability of the method comes mainly from the binary-interaction parameters (BIPs) newly developed for the Peng-Robinson (PR) (Peng and Robinson 1976, 1978) EOS to represent three-phase behavior, including upper critical endpoints, for n-alkane and carbon dioxide (CO2)/n-alkane binaries. The regression part in fluid characterization broadly follows the concept of perturbation from n-alkanes, which was successfully applied for simpler two-phase fluids in our prior research. The algorithm, in its simplest form, uses only the saturation pressure and liquid density at a given composition and reservoir temperature.Case studies are presented to demonstrate the reliability of the algorithm for 90 reservoir fluids and their mixtures with solvents. Predictions are compared with experimental data for up to three phases. Results show that the simple algorithm developed in this research enables the PR-EOS to predict multiphase behavior in spite of the limited data used in the regression. Without the use of the BIPs developed in this research, the PR-EOS may fail to predict three phases, or may provide erroneous three-phase predictions.
Rebecca's Coffee and Tea House: A Strategic Mapping and Balanced Scorecard Case Study
Authors: Kohlmeyer James M. , Samuels Janet A. 
Published: April 2016

ABSTRACT
This case is designed to be used in an undergraduate or M.B.A. managerial/cost accounting course. The case asks students to act as advisors to the owner of a relatively new coffee and tea house. Students' familiarity with coffee houses enhances the real-life application of cost/managerial concepts in the case. The primary learning objectives include understanding quality costs, developing a strategy map, designing a balanced scorecard (BSC), analyzing how some of the BSC measures would be captured and monitored, and articulating the advantages/disadvantages of linking a BSC to employee evaluation. The small business is easily understood by students and, therefore, the case allows for rich class discussion.
Evaluation of intracranial neoplasia and noninfectious meningoencephalitis in dogs by use of short echo time, single voxel proton magnetic resonance spectroscopy at 3.0 Tesla
Authors: Carrera Inés , Richter Henning , Beckmann Katrin , Meier Dieter , Dennler Matthias , Kircher Patrick R. 
Published: April 2016

Abstract
OBJECTIVE To investigate metabolite concentrations of the brains of dogs with intracranial neoplasia or noninfectious meningoencephalitis by use of short echo time, single voxel proton magnetic resonance spectroscopy (1H MRS) at 3.0 T.
ANIMALS 29 dogs with intracranial lesions (14 with neoplasia [3 oligodendromas, 3 glioblastomas multiformes, 3 astrocytomas, 2 lymphomas, and 3 meningiomas] and 15 is with noninfectious meningoencephalitis) and 10 healthy control dogs.
PROCEDURES Short echo time, single voxel 1H-MRS at 3.0 T was performed on neoplastic and noninfectious inflammatory intracranial lesions identified with conventional MRI. Metabolites of interest included N-acetyl aspartate (NAA), total choline, creatine, myoinositol, the glutamine-glutamate complex (Glx), glutathione, taurine, lactate, and lipids. Data were analyzed with postprocessing fitting algorithm software. Metabolite concentrations relative to brain water content were calculated and compared with results for the healthy control dogs, which had been previously evaluated with the same 1H MRS technique.
RESULTS NAA, creatine, and Glx concentrations were reduced in the brains of dogs with neoplasia and noninfectious meningoencephalitis, whereas choline concentration was increased. Concentrations of these metabolites differed significantly between dogs with neoplasia and dogs with noninfectious meningoencephalitis. Concentrations of NAA, creatine, and Glx were significantly lower in dogs with neoplasia, whereas the concentration of choline was significantly higher in dogs with neoplasia. Lipids were predominantly found in dogs with high-grade intra-axial neoplasia, meningioma, and necrotizing meningoencephalitis. A high concentration of taurine was found in 10 of 15 dogs with noninfectious meningoencephalitis.
CONCLUSIONS AND CLINICAL RELEVANCE 1H MRS provided additional metabolic information about intracranial neoplasia and noninfectious meningoencephalitis in dogs.
Comparison of visual metric and planimetry methods for brain tumor measurement in dogs
Authors: Thomson Chris B. , Haynes Kevin H. , Pluhar G. Elizabeth 
Published: April 2016

Abstract
OBJECTIVE To compare the orthogonal diameter (visual metric) method against a manual perimeter tracing (planimetry) method to measure volume of brain tumors in dogs by use of MRI scans.
SAMPLE 22 sets of MRI brain scans pertaining to 22 client-owned dogs with histologically confirmed glioma.
PROCEDURES MRI scans were reviewed by 2 operators, and scans revealing tumors with a degree of gadolinium enhancement that allowed discrimination between tumor tissue and healthy parenchyma were used. Each operator calculated tumor volume for each set of scans twice by use of visual metric and planimetry methods. Inter- and intraoperator variability were assessed by calculation of an agreement index (AI).
RESULTS Mean ± SD intraoperator AIs were 0.79 ± 0.24 for the visual metric method and 0.89 ± 0.17 for the planimetry method. Intraoperator variability for both operators was significantly less when the planimetry method was used than when the visual metric method was used. No significant differences were identified in mean interoperator AI between visual metric (0.68 ± 0.28) and planimetry (0.67 ± 0.31) methods.
CONCLUSIONS AND CLINICAL RELEVANCE The lower intraoperator variability achieved with the planimetry versus visual metric method should result in more precise volume assessments when the same operator performs multiple volume measurements of brain tumors in dogs. Equivocal results for interoperator variability may have been due to method variance or inadequate preliminary training. Additional studies are needed to evaluate the suitability of planimetry for assessing response to treatment.
Ultrasonographic predictors of response of European eels (Anguilla anguilla) to hormonal treatment for induction of ovarian development
Authors: Müller Anna V. , McEvoy Fintan J. , Tomkiewicz Jonna , Politis Sebastian N. , Amigo José M. 
Published: April 2016

Abstract
OBJECTIVE To examine ultrasonographic predictors of ovarian development in European eels (Anguilla anguilla) undergoing hormonal treatment for assisted reproduction.
ANIMALS 83 female European eels.
PROCEDURES Eels received weekly IM injections of salmon pituitary extract (first injection = week 1). Ultrasonography of the ovaries was performed twice during hormonal treatment (weeks 7 and 11). Eels were identified on the basis of body weight as having an adequate response by weeks 14 to 20 or an inadequate response after injections for 21 weeks. Eels were euthanized at the end of the experiment and classified by use of ovarian histologic examination. Ovarian cross-sectional area and size of eel (ie, length3) were used to classify eels (fast responder, slow responder, or nonresponder) and to calculate an ultrasonographic-derived gonadosomatic index. Gray-level co-occurrence matrices were calculated from ovarian images, and 22 texture features were calculated from these matrices.
RESULTS The ultrasonographic-derived gonadosomatic index differed significantly between fast responders and slow responders or nonresponders at both weeks 7 and 11. Principal component analysis revealed a pattern of separation between the groups, and partial least squares discriminant analysis revealed signals in the ovarian texture that discriminated females that responded to treatment from those that did not.
CONCLUSIONS AND CLINICAL RELEVANCE Ovarian texture information in addition to morphometric variables can enhance ultrasonographic applications for assisted reproduction of eels and potentially other fish species. This was a novel, nonlethal method for classifying reproductive response of eels and the first objective texture analysis performed on ultrasonographic images of the gonads of fish.
Evaluation of a feline-specific multiplex, bead-based assay for detection of cytokines, chemokines, growth factors, and other immunologically active proteins in serum and plasma samples from cats
Authors: Halpin Rachel E. , Saunders Rebecca S. , Thompson Beverly J. , Rohde Newgent Allison S. , Amorim Juliana , Melillo Gabrielle N. , DeClue Amy E. 
Published: April 2016

Abstract
OBJECTIVE To evaluate a feline-specific multiplex, bead-based assay system for detection of recombinant and native proteins in serum samples and in EDTA-treated and heparinized plasma samples.
SAMPLE Serum samples and EDTA-treated and heparinized plasma samples from 30 sick cats and 9 healthy client-owned cats and heparinized whole blood samples from 5 healthy purpose-bred cats.
PROCEDURES Ability of the assay system to detect 19 recombinant and native immunologically active proteins in plasma and serum samples from healthy and purpose-bred cats was evaluated via spike-and-recovery tests, assessments of inter- and intra-assay variation, linearity results, and leukocyte stimulation. Effects of various concentrations of heparin and serum matrix solution on percentages of analytes recovered were also evaluated. Analyte concentrations in samples from healthy and sick cats were measured and compared between groups.
RESULTS Percentages of analytes recovered were unsatisfactory for most assays. Serum and heparinized plasma samples yielded better recovery results than did EDTA-treated plasma samples. Use of serum matrix solution did not improve results. Use of heparin concentrations greater than the recommended range affected the results. Linearity of results was difficult to assess because of the poor recovery. For the analytes that were recovered sufficiently for assessment, linearity appeared to be reasonable despite the limited detection.
CONCLUSIONS AND CLINICAL RELEVANCE Poor percentages of analytes recovered and adverse effects of sample protein matrix limited the usefulness of the multiplex, bead-based assay system for measurement of immunologically active proteins in solutions with high protein content; however, recovery results were fairly linear, potentially allowing evaluation of feline plasma or serum samples with high analyte concentrations.
Antimicrobial resistance trends among Salmonella isolates obtained from horses in the northeastern United States (2001–2013)
Authors: Cummings Kevin J. , Perkins Gillian A. , Khatibzadeh Sarah M. , Warnick Lorin D. , Aprea Victor A. , Altier Craig 
Published: April 2016

Abstract
OBJECTIVE To describe the antimicrobial resistance patterns of Salmonella isolates obtained from horses in the northeastern United States and to identify trends in resistance to select antimicrobials over time.
SAMPLE 462 Salmonella isolates from horses.
PROCEDURES Retrospective data were collected for all Salmonella isolates obtained from equine specimens that were submitted to the Cornell University Animal Health Diagnostic Center between January 1, 2001, and December 31, 2013. Temporal trends in the prevalence of resistant Salmonella isolates were investigated for each of 13 antimicrobials by use of the Cochran-Armitage trend test.
RESULTS The prevalence of resistant isolates varied among antimicrobials and ranged from 0% (imipenem) to 51.5% (chloramphenicol). During the observation period, the prevalence of resistant isolates decreased significantly for amoxicillin—clavulanic acid, ampicillin, cefazolin, cefoxitin, ceftiofur, chloramphenicol, and tetracycline and remained negligible for amikacin and enrofloxacin. Of the 337 isolates for which the susceptibility to all 13 antimicrobials was determined, 138 (40.9%) were pansusceptible and 192 (57.0%) were multidrug resistant (resistant to ≥ 3 antimicrobial classes). The most common serovar isolated was Salmonella Newport, and although the annual prevalence of that serovar decreased significantly over time, that decrease had only a minimal effect on the observed antimicrobial resistance trends.
CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that current antimicrobial use in horses is not promoting the emergence and dissemination of antimicrobial-resistant Salmonella strains in the region served by the laboratory.
Effect of hoof boots and toe-extension shoes on the forelimb kinetics of horses during walking
Authors: Amitrano Fernando N. , Gutierrez-Nibeyro Santiago D. , Schaeffer David J. 
Published: April 2016

Abstract
OBJECTIVE To determine and compare the effect of hoof boots (HBs) and shoes with a toe extension on stance duration, ground reaction force, and sole length in contact with the ground in nonlame horses during walking.
ANIMALS 6 nonlame Standardbreds.
PROCEDURES Force plate gait analyses of the forelimbs were performed while the horses were walking barefoot before manipulation of feet (baseline), while the horses were walking fitted with HBs, while the horses were walking shod with toe-extension shoes, and while the horses were walking barefoot after shoe removal. Horses underwent radiography of both forelimb feet to determine the sole length in contact with the ground when barefoot, wearing HBs, and shod with toe-extension shoes. Stance duration, ground reaction force, and sole length were compared among the various walking sessions.
RESULTS Compared with baseline findings, stance duration increased significantly when horses were fitted with HBs (7%) or toe-extension shoes (5%). Peak forelimb ground reaction force was similar among walking sessions; however, time of braking force peak was significantly greater during the stance phase only when horses wore HBs. Also, the sole length in contact with the ground was significantly longer in horses fitted with HBs (14.3 cm) or shod with the toe-extension shoes (17.6 cm), compared with that for one of the barefoot hooves (12.7 cm).
CONCLUSIONS AND CLINICAL RELEVANCE In nonlame horses, use of HBs prolonged the stance time and time of braking force peak, which is indicative of a slower deceleration phase during limb impact with the ground. Also, the use of HBs prolonged the deceleration phase of the stride and increased the sole length in contact with the ground.
Effects of ischemia and reperfusion on eosinophilic accumulation and distribution in mucosa of equine jejunum and colon
Authors: Rötting Anna K. , Freeman David E. , Constable Peter D. , Eurell Jo Ann C. , Wallig Matt A. 
Published: April 2016

Abstract
OBJECTIVE To evaluate the eosinophilic response in intestinal mucosa of horses with intestinal ischemia and reperfusion or with strangulation of the jejunum or colon.
SAMPLE Mucosal samples from horses with naturally occurring strangulation (n = 24 horses) or distention (n = 6) of the jejunum or colon (11), with experimentally induced ischemia and reperfusion of the jejunum (6) or colon (15), or that were euthanized for reasons other than gastrointestinal tract disease (13).
PROCEDURES Mucosal samples were collected and grouped by type of intestinal injury. Slides were stained with Luna eosinophil stain and histologically examined to determine eosinophil accumulation and distribution. Number of eosinophils per mm2 of mucosa was calculated as a measure of eosinophil accumulation. Additionally, mucosa was categorized into 5 regions; the percentage of eosinophils in each of the 5 regions, relative to the total eosinophil count in all regions, was determined.
RESULTS Eosinophil migration toward and onto the luminal surface was evident in tissues after ischemia and reperfusion and after naturally occurring strangulating disease of the jejunum and colon, as indicated by a decrease in the number of eosinophils near the muscularis mucosa and an increase in the number of eosinophils on or near the luminal surface. Ischemia alone did not change eosinophil distribution in the jejunum or colon.
CONCLUSIONS AND CLINICAL RELEVANCE Eosinophils responded to mucosal damage evoked by ischemia and reperfusion by migration toward and onto the luminal surface. This migration could represent an important component of the inflammatory response to injury in equine gastrointestinal mucosa.
Collateral circulation in ferrets (Mustela putorius) during temporary occlusion of the caudal vena cava
Authors: Calicchio Kristina W. , Bennett R. Avery , Laraio Leonard C. , Weisse Chick , Zwingenberger Allison L. , Rosenthal Karen L. , Johnston Matthew S. , Campbell Vicki L. , Solomon Jeffrey A. 
Published: April 2016

Abstract
OBJECTIVE To determine whether extent of collateral circulation would change during temporary occlusion of the caudal vena cava (CVC) in ferrets (Mustela putorius), a pressure change would occur caudal to the occlusion, and differences would exist between the sexes with respect to those changes.
ANIMALS 8 adult ferrets (4 castrated males and 4 spayed females).
PROCEDURES Ferrets were anesthetized. A balloon occlusion catheter was introduced through a jugular vein, passed into the CVC by use of fluoroscopy, positioned cranial to the right renal vein, and inflated for 20 minutes. Venography was performed 5 and 15 minutes after occlusion. Pressure in the CVC caudal to the occlusion was measured continuously. A CBC, plasma biochemical analysis, and urinalysis were performed immediately after the procedure and 2 or 3 days later.
RESULTS All 8 ferrets survived the procedure; no differences were apparent between the sexes. Vessels providing collateral circulation were identified in all ferrets, indicating blood flow to the paravertebral venous plexus. Complications observed prior to occlusion included atrial and ventricular premature contractions. Complications after occlusion included bradycardia, seizures, and extravasation of contrast medium. Mean baseline CVC pressure was 5.4 cm H2O. During occlusion, 6 ferrets had a moderate increase in CVC pressure (mean, 24.3 cm H2O) and 2 ferrets had a marked increase in CVC pressure to > 55.0 cm H2O.
CONCLUSIONS AND CLINICAL RELEVANCE Caval occlusion for 20 minutes was performed in healthy ferrets with minimal adverse effects noted within the follow-up period and no apparent differences between sexes. The CVC pressure during occlusion may be prognostic in ferrets undergoing surgical ligation of the CVC, which commonly occurs during adrenal tumor resection.
Heat Stress Related Physiological and Metabolic Traits in Peanut Seedlings
Authors: Singh D. , Balota M. , Collakova E. , Isleib T.G. , Welbaum G.E. , Tallury S.P. 
Published: April 2016

ABSTRACT
To maintain high yields under an increasingly hotter climate, high temperature resilient peanut cultivars would have to be developed. Therefore, the mechanisms of plant response to heat need to be understood. The objective of this study was to explore the physiological and metabolic mechanisms developed by virginia-type peanut at early growth stages in response to high temperature stress. Peanut seedlings were exposed to 40/35 C (heat) and 30/25 C (optimum temperature) in a growth chamber. Membrane injury (MI), the Fv/Fm ratio, and several metabolites were evaluated in eight genotypes at four time-points (day 1, 2, 4, and 7) after the heat stress treatment initiation. Even though we were able to highlight some metabolites, e.g., hydroxyproline, galactinol, and unsaturated fatty acid, explaining specific differential physiological (MI) responses in peanut seedlings, overall our data suggested general stress responses rather than adaptive mechanisms to heat. Rather than individual metabolites, a combination of several metabolites better explained (41 to 61%) the MI variation in heat stressed peanut seedlings. The genotype SPT 06-07 exhibited lower MI, increased galactinol, reduced hydroxyproline, and higher saturated vs. unsaturated fatty acid ratio under heat stress compared to other genotypes. SPT 06-07 was also separated from the other genotypes during hierarchical clustering and, based on this and previous fieldwork, SPT 06-07 is proposed as a potential source for heat tolerance improvement of virginia-type peanut.
Phenotyping Peanut Genotypes for Drought Tolerance
Authors: Luis J.M. , Ozias-Akins P. , Holbrook C.C. , Kemerait R.C. , Snider J.L. , Liakos Vasilis 
Published: April 2016

ABSTRACTDrought and heat stress can result in aflatoxin contamination of peanuts especially when this occurs during the last three to six wk of the growing season. Identifying drought-tolerant genotypes may aid in development of peanuts that are less susceptible to aflatoxin contamination. Research was conducted to phenotype seven peanut genotypes based on their response to drought stress. Six peanut genotypes that have exhibited lower aflatoxin and/or drought tolerance in previous researches (Tifguard, Tifrunner, Florida-07, PI 158839, NC 3033, C76-16) were compared to an aflatoxin-susceptible genotype, A72. The phenotyping methods included visual ratings, chlorophyll fluorescence (PIABS, ϕEO, and Fv/Fm), SPAD chlorophyll meter reading (SCMR), normalized difference vegetation index (NDVI), canopy temperature (CT), canopy temperature depression (CTD), and pod yield. Based on these traits, Tifguard and Tifrunner exhibited greater drought tolerance mechanisms than the other genotypes and may be good candidates to be incorporated in future drought tolerance studies. After the aflatoxin content of the different genotypes was measured, aflatoxin contamination showed high correlations with visual ratings (0.85), CTD (0.81), NDVI (0.79), and CT (0.73), and moderate correlations with Fv/Fm (0.62) and SCMR (0.57) (P ≥ 0.05). These easily measurable, rapid and cost-effective phenotyping methods may be used as alternative to more tedious and costly methods of identifying genotypes that are less susceptible to aflatoxin contamination. Using a combination of these methods is beneficial but not always practical. The combined use of visual ratings, CTD and NDVI is advised for initial evaluation of drought tolerance in peanut genotypes.
Three Inoculation Methods for Evaluating Sclerotinia Blight Resistance in Peanut
Authors: Bennett R.S. , Payton M.E. , Chamberlin K.D. 
Published: April 2016

ABSTRACT
Laboratory-based assays for screening germplasm for resistance to Sclerotinia blight in peanuts can be conducted year-round, and thus may accelerate progress in breeding for resistant plants. Three previously proposed inoculation methods (using main stems of intact plants, detached main stems, or detached leaflets) were compared on six peanut genotypes known to represent range of resistance to Sclerotinia blight in the field or laboratory. The intact plant and detached main stem assays identified the most resistant and susceptible genotypes, but different results were obtained from either assay with Red River Runner, a cultivar with intermediate resistance to Sclerotinia blight. No differences among genotypes were observed with the detached leaflet assay. The sensitivity ratio was used to compare the three inoculation methods and identified the intact plant assay as the method with the smallest error variance. These results help identify the most efficient method for assaying physiological resistance to Sclerotinia blight in peanut.