bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Kasus Difteri di Provinsi DKI Jakarta Tahun 2015-17 Desember 2017
Authors: Oktaviannoor Husda , Djuwita Ratna 
Published: September 2024

Background: Diphtheria is a contagious disease whose transmission is very fast and can cause death especially in children. In 2017 it was reported, there were 11 provinces in Indonesia experiencing diphtheria outbreaks, one of which is DKI Jakarta Province. This study aims to see an overview of diphtheria cases in DKI Jakarta in 2015 - December 17, 2017.Methods: This research is a descriptive study with a case report design. The sample in this study amounted to 59 cases. The implementation was carried out on 25 to 29 December 2017.Result: DKI Jakarta Province reported 7 diphtheria cases in 2015, 14 new cases in 2016 and 38 cases in January to 17 December 2017. Where the highest cases were in East Jakarta with the number of 18 cases from 2015 – December 17, 2017. And the number of diphtheria cases is more common in men, especially in children aged 0 - 9 years. In the 46th week of 2017 was the peak report on the incidence of diphtheria as many as 12 new cases in 1 week so that DKI Jakarta Province was declared to have an outbreak of diphtheria.Conclusion : Cases of diphtheria in DKI Jakarta from 2015 - December 17, 2017 continue to increase so special efforts are needed to prevent transmission of this disease.
Efek Antidiabetes Kombinasi Ekstrak Mengkudu (Morinda citrifolia) dan Kunyit (Curcuma longa) pada Tikus yang dibuat Hiperglikemik
Authors: Iddahan Viqi , Sutiningsih Dwi , Martini Martini 
Published: September 2024

Background: Diabetes Mellitus is a disease characterized by hyperglycemia in a long time can cause the damage of pancreatic beta cells. Morinda citrifolia contains xeronine that can regenerate damaged pancreatic beta cells. While Curcuma longa contains curcumin which acts as an antioxidant will stabilize free radicals so it can inhibit pancreatic beta cell damage and stimulate insulin secretion.Methods: The study aim to analyze the effect of a combination of Morinda Citrifolia and Curcuma Longa in reducing blood glucose levels, increasing body weight and pancreatic histopathology in hyperglycemic mice. This type of research is an experiment with the Post Test Only Control Group. A total of 25 mice were divided into 5 groups namely PI (250 mg/dL), PII (500 mg/dL), PIII (750 mg/dL), K(+), and K(-). Blood glucose level was observed for 21 days followed by observation of pancreatic histopathology.Result: The results showed the percentage of glucose blood reduction occurred in the PI group (56.11%) and significantly different from negative controls (35.05%). There was no difference in body weight (p=0.7) and number of langerhans islet (p=0.360) in all treatment groups. The diameter of the Langerhans islet of the PI group (200.8 μm) was significantly different from the negative control (114.8 μm). (p<0.05Conclusion : The combination of Morinda citrifolia and Curcuma longa extract can reduce blood glucose levels and increase body weight but not be able to optimally repair pancreatic islet damage.
Health Behavior pada Pasien HIV AIDS di Kota Salatiga
Authors: Desi Desi , Lase Priskila , Anwar Muh Aziz 
Published: September 2024

Background: Healthy behavior is a person's reaction to improve, fight for, maintain his health. Healthy behavior is related to individual actions such as exercise, rest, fulfillment of nutritional needs, personal care and hygiene, as well as cleanliness of reproductive organs and use of condoms for people living with HIV/AIDS (ODHA) so that they are not transmitted to others, so it is important to implement life behaviors healthy. The Salatiga City Health Office explained that in 2017 the number of HIV/AIDS sufferers reached 250, in 2018 there were 271 people, in 2019 there were 285 people who were infected by July 2020 there were 300 cases of HIV/AIDS. This study aims to determine the description of healthy behavior in HIV/AIDS sufferers in the City of Salatiga.Methods is qualitative research with a case study approach. Respondents in this study were 4 people infected with HIV/AIDS. It was held from September to November 2020. Data was collected by means of in depth interviews and using interview guide sheets.Results Healthy behavior carried out by ODHA to maintain and strive for their health is by doing physical activity and useful sports, healthy and nutritious nutrition, maintaining personal hygiene and reproductive hygiene, providing and using condoms when engaging in sexual activity, adhering to taking ARVs, and groups. peer support (KDS) which has a good influence on awareness of the healthy life of HIV/AIDS patients in Salatiga City.Conclusion Healthy behavior has an important role in the condition of PLWHA in Salatiga which is able to make ODHA more confident and productive.
The Influence of Parental Role on Adolescent Sexual Behaviour and HIV/AIDS in KwaZulu-Natal, South Africa.
Authors: Ringisai Lovemore 
Published: September 2024

Background: HIV/AIDS risky behaviour remains a critical health concern for adolescents, specifically at high school level. In South Africa, the rapid increase of risky lifestyles and sexual behaviours among adolescents could be mainly attributed to poor parental skills and broken family structures. Four identified sexual risk behaviours that are of concern in South Africa are age at sexual debut, multiple sexual partners, condom use and transactional sex.Methods: Data was collected using a quantitative cross-sectional survey with samle consist with 450 male and female high school adolescents between 14 to 18 years from 3 different South African school settings. Collected data was analyzed using SPSS descriptive statistics procedure.Result: 79.7% of the respondents had only one parent still alive with 4.9 % of the respondents indicated to have lost both parents. Only 13.5% of the respondents were from a nuclear family. The majority of the respondents were (41.2%) living with grandparents. This high level of family disintegration, parental absence and poor parenting skills in South Africa exposed 73.3% (330) of the respondents to early sexual debut, transactional sex, unprotected sex and having multiple sexual partners. The study proved that there is a statistical association between guardianship and age at sexual debut; guardianship and multiple sexual partners; guardianship and condom use; guardianship and transactional sex.Conclusion : The revealed significant high risk sexual behaviour among adolescents in KwaZulu-Natal should inform Health and educational authorities to utilize these key findings to design more effective local strategies to train and assist parents and caregivers on parenting skills
“As a Muslim…”: on the importance of intercultural responsibility in transnational cultural exchanges
Authors: Nattheeraphong Anyarat , Jenks Christopher 
Published: September 2024

Abstract
Cultural exchange is increasingly becoming an essential activity of higher education as the world continues to experience widespread ethnocentrism because of war, migration, political provocation, and nationalism. Research in areas related to cultural exchange have also increased with the rise of teacher and student mobility, leading to an exciting body of scholarship. Several aspects of intercultural communication, however, remain under-researched in the study of cultural exchange. One such example is intercultural responsibility. The current study adds to this body of work by investigating how Muslim students that were part of a cultural exchange program in Thailand used notions of intercultural responsibility to make sense of their encounters and identities. The findings show that national and religious identities are both barriers to, and resources for, intercultural communication in general, and the social practices of Muslim students in particular. Intercultural responsibility is important to scholars and educators, as it can empower students to become agentive in their participation in intercultural communication, allowing them to reflect on and utilize their linguistic, cultural, and historical repertoire when interacting with individuals and communities that do not share their same cultural traditions and practices.
Dialektwandel als Systemwandel: Die Genuskongruenz bei den Numeralien

zwei und

drei in den deutschen Dialekten und darüber hinaus
Authors: Pheiff Jeffrey 
Published: September 2024

Abstract
This paper investigates the gender agreement behavior of the cardinal numbers two and three in various German(ic) dialects in attributive function using a corpus of dialect grammars and linguistic atlases. In contrast to previous studies which have investigated certain regions, this paper focuses the entire German-speaking area. The results show diatopic differences in gender agreement depending on the numeral as well as certain tendencies in its development through a comparison of the two datasets. The paper closes with a discussion of the differences between the standard language and the dialects, and proposes that the loss of gender agreement was set in motion by dialect sound mergers.
Evaluation of the analytical and clinical performance of a high-sensitivity troponin I point-of-care assay in the Mersey Acute Coronary Syndrome Rule Out Study (MACROS-2)
Authors: Dakshi Ahmed , Hatherley James , Collinson Paul , Phillips Suzannah , Bailey Lisa , Miller Guy , Shaw Matthew , Khand Aleem 
Published: September 2024

Abstract

Objectives
The objective of this study is to evaluate the analytical and diagnostic performance of a high-sensitivity point-of-care (POC) cardiac troponin I assay, the Quidel TriageTrue™ (QuidelOrtho Inc, San Diego, USA), compared to central laboratory testing (CLT) in accelerated diagnostic protocols (ADP) in real time in a clinical environment.

Methods
In a nested sub-study of a pragmatic randomised control trial, consecutive patients with suspected acute coronary syndrome (ACS) and chest pain <12 h duration were randomised to the ESC 0/1 and 0/3-h ADP. Subjects underwent sampling for Quidel TriageTrue POC hs-TnI whole blood and plasma, CLT hs-TnT Roche Elecsys and a validated, NICE approved CLT High sensitivity cardiac troponin I (hs-TnI) (Siemens Attellica) at each time point. Assay imprecision was assessed by repeat analysis of whole blood samples at three levels (low, near 10 % CV 5–10 ng/L, medium, approximating 99th percentile 15–25 ng/L and high, 3–5 times the 99th percentile, 60–100 ng/L). Final diagnosis was adjudicated at 6 weeks by Roche hs-TnT using the 4th universal definition of myocardial infarction (MI).

Results
A total of 1,157 patients consented and had both investigational POC whole blood and plasma and central lab hs-cTn available. The median age was 59, 47.2 % were female and 15 % had suffered a previous MI. Assay imprecision of whole blood POC TriageTrue revealed 10 % CV at 8.6 ng/L (>50 % lower than 99th percentile [20.5 ng/L]) and a 20 % CV at 1.2 ng/L. Receiver operator characteristics (ROC) curves were computed for each assay against adjudicated index type 1 MI to study clinical performance. At all-time points there were excellent performance for whole blood POC TriageTrue: area under the curve (AUC) 0.97 [95 % CI 0.94–098], 0.98 [95 % CI 0.97–1.00] and 0.95 [95 % CI 0.92–0.98] at time 0, 1 and 3 h respectively. There was statistical equivalence for performance of whole blood and plasma POC TriageTrue hs-TnI and laboratory Siemens Atellica hs-TnI.

Conclusions
The whole blood POC TriageTrue hs-TnI assay demonstrates imprecision levels consistent with high sensitivity characteristics and has a clinical performance equivalent to an established, validated and NICE approved laboratory Siemens Atellica hs-TnI.
External quality assessment performance in ten countries: an IFCC global laboratory quality project
Authors: Bais Renze , Vassault Anne , Blasutig Ivan M. , Dabla Pradeep Kumar , Lin Ji , Perret-Liaudet Armand , Thomas Annette , Cendejas Kandace A. , Wheeler Sarah E. , Giannoli Jean-Marc , Meng Qing H. , Amann Egon P. 
Published: September 2024

Abstract

Objectives
This study aimed to assess the validity of external quality assessment (EQA) laboratory results across various cultural and environmental contexts and to identify potential improvement areas.

Methods
The International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Task Force on Global Laboratory Quality (TF-GLQ) conducted a 2-year study (2022 and 2023) in which EQA materials, related software and online training was provided by a commercial vendor to 100 laboratories in ten IFCC member society countries. The results were analysed on a monthly basis by the TF-GLQ, to show the number of submissions per country, tests per lab, acceptability rates, random failures and to get a measure of which analytes performed poorly.

Results
The EQA material was dispatched on a quarterly basis. Some countries had problems with customs releasing the material in a timely manner, resulting in laboratories not receiving them on time leading to no submission. We report here the results for the second year of the survey. The number of examinations varied between laboratories, ranging from seven to 84 analytes. Of the ten countries surveyed, six averaged greater than 90 % acceptable results over the whole 12-months cycle, one had unacceptable results for two of the nine months they returned results and the other four were considered to not perform to an acceptable standard.

Conclusions
All 100 participating laboratories indicated satisfaction with the EQA survey and related services, including on-site training, and report handling. However, specimen receiving issues, suggest benefits in dispatching materials for a full 12-month cycle. Significant discrepancies in EQA performance indicate that four countries require long-term assistance, training and guidance. To ensure reliable patient results, promoting EQA in certain countries is essential to achieve the required level of quality.
Evaluating polyphenol and ascorbic acid contents, tannin removal ability, and physical properties during hydrolysis and convective hot-air drying of cashew apple powder
Authors: Pham Binh An , Tran Thi Yen Nhi , Nguyen Tung Xuan Tan , Dao Tan Phat , Ngo Hoang Duy , Vu Ngoc Duc 
Published: September 2024

Abstract
Cashew apple is a source of by-products in the cashew industry. Powder products provide convenience to the process of use, transport, and preservation of nutrients. In this study, the production of soluble powder from cashew apples was developed through the investigation of hydrolysis process (time, temperature, and enzyme tannase) and convective drying conditions (temperature and maltodextrin content). The following indicators are evaluated, such as the total polyphenol content (TPC), total tannin content, total ascorbic acid, solubility, turbidity, and color. The results have shown that TPC increased by 1.67 times, and more than 50% of tannins was removed after the hydrolysis process. At the same time, the efficiency of the process over 30% under all processing conditions was evaluated. These results are the foundation for the development of cashew apple powder and related products, thereby improving the economy of the cashew industry in Vietnam and the world.
Structural features and tectonic activity of the Weihe Fault, central China
Authors: Tian Qinhu , Wang Shidi , Li Xiaoni , Liu Lei 
Published: September 2024

Abstract
The study of tectonic activity holds great significance in assessing historical and modern seismic risks. The Weihe Graben is a significant intracontinental graben system in China, with numerous active faults that have caused a series of earthquakes, including the Huaxian great earthquake (M ∼ 8.5) in 1556 with approximately 830,000 deaths. Despite the obvious spatial relationship between the Weihe fault (WF) and these earthquakes, detailed research on the fault is still lacking. Various techniques including remote sensing images, digital elevation model, shallow seismic lines, trench excavation, drilling sections, and optically stimulated luminescence dating, have been utilized to obtain the following results: (1) The WF passes through the scarp of the Weihe River terrace in the north of Xianyang and can be divided into east and west sections at Jinjia village; (2) The WF is a normal fault that strikes northeast and dips south with a dipping angle of 65°–75°; (3) The fault has been active during the Holocene; (4) The vertically offset and dating results suggest that the fault activity has gradually decreased since the late Pleistocene, and the vertical slip rate during the Holocene is only 0.04–0.13 mm/year.
Insights into a new class of unbounded operators
Authors: Bahloul Aymen 
Published: September 2024

Abstract
The aim of this paper is to introduce the new class of left and right B-Weyl operators, which naturally extends the conventional concepts of left and right Weyl operators. Our contributions encompass demonstrating the stability of the left (and right) B-Weyl operators under small perturbations. We further characterize the left (and right) B-Weyl operators as the direct sum of a closed left (and right) Drazin invertible operator and a finite rank operator. Additionally, we present some characterizations of the left and right B-Weyl spectra, utilizing the left and right Drazin spectra as essential components. Furthermore, our obtained results play a pivotal role in exploring the interrelations between the left and right B-Weyl spectra and other spectra integral to the realm of B-Fredholm theory. This paper seeks to enhance and extend the recent research explored in
[F. Abdmouleh and T. Ben Lakhal,
Left and right B-Fredholm operators,
Ukrainian Math. J. 74 2023, 10, 1479–1489] to a larger class in the unbounded B-Fredholm operators theory.
Hither and Yawn: Malory’s Drowsy Lancelot in the
Morte Darthur
– ‘shew me somthynge of that I seke’ (MD
773.23–26).
Authors: Hanks Jr D. Thomas 
Published: September 2024

Abstract
Early in Sir Thomas Malory’s Morte Arthur Merlin predicts that the child Lancelot will become ‘the moste man of worship of the world’ (MD 100.7). Later, in King Arthur and the Emperour Lucius, the still-youthful Lancelot is heralded as having ‘no felowe’ in ‘wyse wytte and . . gret strengthe of his ayge’ (MD 168.17–19). Still a major character in the next four sections of the Morte Darthur – ‘Sir Launcelot du Lake’, ‘Sir Gareth of Orkney’, and the two ‘books’ of ‘Sir Tristram […]’, he loses his dominant role in The Sankgreal. As the Grail Quest begins, in fact, Malory revises his presentation of his chief knight. Thus Lancelot learns from a suddenly-appearing damsel that he is now only ‘the best knyght […] of ony synfull man of the worlde’ (MD 672.9, 14–19). Thus lessened, he begins his Quest only to be lessened further, first defeated by Galahad, then by virtually every knight he challenges. Moreover, he is beset by sudden nap-attacks. Thus hampered – by his unconfessed sin, we learn – Lancelot fails at almost every chivalric endeavor he attempts in the Quest. The ‘hero’ of The Sankgreal is Galahad, of course – but the thematic center and the most ‘conflicted’ character is Lancelot – who, contradicting his earlier valor and success, yawns or at least naps through many of the high points of The Sankgreal. Ironically, his greatest success is a final defeat – for which he thanks God.
MCMVDRP: a multi-channel multi-view deep learning framework for cancer drug response prediction
Authors: Li Xiangyu , Shi Xiumin , Li Yuxuan , Wang Lu 
Published: September 2024

Abstract
Drug therapy remains the primary approach to treating tumours. Variability among cancer patients, including variations in genomic profiles, often results in divergent therapeutic responses to analogous anti-cancer drug treatments within the same cohort of cancer patients. Hence, predicting the drug response by analysing the genomic profile characteristics of individual patients holds significant research importance. With the notable progress in machine learning and deep learning, many effective methods have emerged for predicting drug responses utilizing features from both drugs and cell lines. However, these methods are inadequate in capturing a sufficient number of features inherent to drugs. Consequently, we propose a representational approach for drugs that incorporates three distinct types of features: the molecular graph, the SMILE strings, and the molecular fingerprints. In this study, a novel deep learning model, named MCMVDRP, is introduced for the prediction of cancer drug responses. In our proposed model, an amalgamation of these extracted features is performed, followed by the utilization of fully connected layers to predict the drug response based on the IC50 values. Experimental results demonstrate that the presented model outperforms current state-of-the-art models in performance.
Integrating the probe and singular sources methods
Authors: Ikehata Masaru 
Published: September 2024

Abstract
The probe and singular sources methods are two well-known classical direct reconstruction methods
in inverse obstacle problems governed by partial differential equations.
In this paper, by considering an inverse obstacle problem governed by the Laplace equation in a bounded domain as a prototype case,
an integrated theory of the probe and singular sources methods is proposed.
The theory consists of three parts: (i) introducing the singular sources method combined with the notion of
the probe method;
(ii) finding a third indicator function whose two ways decomposition yields the indicator functions in the probe and singular sources methods;
(iii) finding the completely integrated version of the probe and singular sources methods.
Genetic advances in neurodevelopmental disorders
Authors: Gao Shilin , Shan Chaoyi , Zhang Rong , Wang Tianyun 
Published: September 2024

Abstract
Neurodevelopmental disorders (NDDs) are a group of highly heterogeneous diseases that affect children’s social, cognitive, and emotional functioning. The etiology is complicated with genetic factors playing an important role. During the past decade, large-scale whole exome sequencing (WES) and whole genome sequencing (WGS) have vastly advanced the genetic findings of NDDs. Various forms of variants have been reported to contribute to NDDs, such as de novo mutations (DNMs), copy number variations (CNVs), rare inherited variants (RIVs), and common variation. By far, over 200 high-risk NDD genes have been identified, which are involved in biological processes including synaptic function, transcriptional and epigenetic regulation. In addition, monogenic, oligogenic, polygenetic, and omnigenic models have been proposed to explain the genetic architecture of NDDs. However, the majority of NDD patients still do not have a definitive genetic diagnosis. In the future, more types of risk factors, as well as noncoding variants, are await to be identified, and including their interplay mechanisms are key to resolving the etiology and heterogeneity of NDDs.
Mechanical and metallurgical properties of a glass fiber-reinforced Al7075 hybrid composite produced by infiltration and after aging and abrasion
Authors: Kaner Sidem 
Published: September 2024

Abstract
Within the scope of this study, composite structures were produced by reinforcing Al7075 with 6 mm size glass fiber (GF) scrap at different weight rates (2–3 %) using the infiltration method. Mechanical and metallurgical examination of unreinforced Al7075 samples and reinforced Al7075 composite samples were carried out. After the aging heat treatment of the samples, pin-on-disc wear and hardness tests were performed. FESEM and EDS analyses were conducted to examine the hardness and microstructural changes caused by the applied processes on the samples. It was observed that GF reinforcement increased the hardness of the material and there was full wettability between Al 7075 and GF. Thus, wear resistance increased. The highest hardness and wear resistance were obtained in the 6 h aged 2 wt.% GF-reinforced Al 7075 matrix hybrid composite sample. In addition, it was observed that the distribution of GF scrap added as reinforcement at a rate of 2 wt.% in Al 7075 was homogeneous, and the hardness measurements taken from different areas were similar.