bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migraine in antiphospholipid syndrome and hereditary thrombophilia: pregnancy-related clinical and diagnostic features and therapeutic issues
Authors: Voskresenskaya O. N. , Dashdamirova L. R. , Khizroeva J. Kh. , Makatsariya A. D. , Bitsadze V. O. 
Published: October 2024

Introduction. Migraine is one of the most common primary headaches and a risk factor for cardiovascular and cerebrovascular diseases. Antiphospholipid syndrome (APS) and hereditary thrombophilia (HT) causing pathological pregnancy are highly associated with migraine. Timely migraine recognition related to APS and HT facilitates earlier initiation of thrombophilia pathogenetic therapy and prevention of potential complications.Aim: to analyze the literature data on migraine clinical and diagnostic features in APS and HT as well as pregnancy-related therapeutic issues.Materials and Methods. A search for scientific literature was conducted in electronic databases including PubMed, Google Scholar, eLibrary from 2004 until May 2024. The search methodological basis included the presence of the following keywords and their combinations in Russian and English: "migraine", "antiphospholipid syndrome", "thrombophilia", "migraine and pregnancy", "migraine and thrombophilia", "migraine and cardiovascular diseases". As a result, a total of 184 publications were identified. Next, 62 articles were included in the review.Results. At the current stage, neurologists have no means to diagnose migraine in APS and HT based on headache-intrinsic characteristics. Pregnancy increases a risk of thrombotic complications. A migraine observed in patient's history should be crucial while assessing pregnancy-related obstetric risk. While diagnosing migraine, neurologists need to examine patient obstetric history. The data on most effective and safe therapy for pregnancy-related migraine attacks remain scarce.Conclusion. The frequent association between APS and HT with migraine, the lack of clear migraine clinical features in thrombophilia, patients’ reproductive age, and the high risk of thrombotic complications necessitate collaboration between neurologists and obstetricians-gynecologists for timely diagnostics and management of such patients. The impact of various types of antithrombotic therapy on migraine course requires further clarification. It is promising to conduct studies able to determine of whether migraine attack prevention can avoid adverse pregnancy outcomes in women with former migraine.
Milestones in the Life of Prince Svyatoslav Igorevich: Towards the Reconstruction of the Chronography of Events in the Rurikid Polity of the 930s — early 970s
Authors: Schavelev Aleksey 
Published: October 2024

The paper proposes a reconstruction of the chronological list of internal political events in the chiefdom of the Rurikid lineage in the 930s — 970s and the main milestones in the life of Prince Svyatoslav Igorevich. The study is based on available synchronous documentary and narrative Greek and Latin texts. As an additional source, the texts of old Russian chronicles, written in the mid-11th — early 12th centuries, and respectively late for the history of the 10th century, are used. These records are critically assessed for transformation in historical memory and intentional ideologically motivated distortions. A comparison of these two sets of diverse data allows us to create a basis for interpreting in our own way the most significant segment of the political history of the Rurikid polity. As a result, it turns out that Prince Svyatoslav Igorevich ruled the Rurikid polity for no more than five to seven years, he made two military campaigns — against the Vyatichi and the Bulgarians. No other domestic or foreign policy actions of this leader of Rus’are known; accordingly, any speculation on these topics remains nothing more than guesswork of varying degrees of originality.
Enmity and Hatred in Piedmont: the Peasant Uprisings of 1799 Viewed by Contemporaries
Authors: Mitrofanov Andrey 
Published: October 2024

One of the important consequences of the French occupation of Piedmont was the peasant and urban uprisings that began in December 1798 and continued intermittently until 1801. This topic has been extensively researched by historians because it is closely connected with the history of the «republican triennium» of 1796—1799 in Italy, with the question of the formation and fall of the republican regime on the territory of Piedmont and with the history of the Italian campaign of the Russian-Austrian army under the command of Suvorov. The author of the article proposes to follow the course of the uprisings in Acqui, Strevi, Carmagnola, Mondovi. The main sources for this article: G. Cerise&apos;s report to the provisional government, fragments of the Chronicle of Acqui by G. Chiabrera, G. Maranda&apos;s pamphlet “A picture of Piedmont under the rule of kings with a brief review of the Waldensians and a note on the Barbets”, and F. Bongioanni&apos;s “Memoirs of a Jacobin”. The purpose of this small study is to clarify the known picture of events and to analyze the attitude of the authors of these sources to the peasantry, which became the main force in this popular war against the French and the Republicans. According to the author of the article, eyewitnesses of the uprisings deny the peasantry the right to be considered an independent force with its own traditions and expectations, see in the peasantry a threat to order and private property, an obedient tool in the hands of royalists — the nobility and clergy, which skillfully used them. It is characteristic that these sources do not touch upon the struggle of the Piedmontese peasantry with large land tenants and seignorial privileges, which was very acute in the late 1790s. The authors under consideration almost do not touch upon the social and economic causes of the uprisings, but emphasize the importance of the religious factor. At the same time the uprisings of 1799 cannot always be considered only and exclusively peasant uprisings: urban and rural uprisings occurred more often than not synchronously. The brutal suppression of the uprisings did not help to save the republican regime in Piedmont, but these bloody episodes remained in the national memory for a long time.
Identification of Formalin and Borax Content in Salted Fish Circulating in The World West Bolangitang District
Authors: Isa Ishak , Kasim Sesha Ramadhani , Taupik Muhammad 
Published: October 2024

Salted fish is a well-known dish in Indonesia. Nationally, salted fish is one of the important fishery products, with almost 65% of fishery products being processed and preserved through salting. Formalin is a solution of 30-50% formaldehyde gas (CH2O), commonly used for embalming, disinfecting, and as an antiseptic, as well as in plastics, antifreeze, paper, carpet, textile, construction materials, paint, and furniture industries. Borax is a chemical compound known as sodium tetraborate (Na2B4O7.10 H₂O). Borax or boric acid is usually used in making detergents and antiseptics. The purpose of this research is to identify the presence of formalin and borax in salted fish and to determine the levels of formalin and borax in salted fish. This research employed qualitative analysis, using the permanganate, citric acid, and chromotropic acid methods for formalin detection. Turmeric paper, flame test, and AgNO3 precipitation methods were used for borax detection. Meanwhile, the quantitative analysis was conducted using the UV-Vis Spectrophotometry method. Based on the qualitative research results, all four samples tested negative for formalin, while one sample tested positive for borax. Consequently, the sample that tested positive for borax underwent quantitative analysis, revealing a borax level of 0,0975 g/kg in sample B.
The The Commercial Value of Guangxi Miao Batik in Douyin Short Video Communication
Authors: Ma Junrui 
Published: October 2024

Purpose-This study analyzes the current situation and characteristics of the communication of Guangxi Miao batik on the Chinese social media (Douyin), and explores the commercial value of this Chinese intangible cultural heritage spread on Douyin.
Methodology-This research uses a qualitative research method which collects data by interview method and network observation method. To use the theory of symbolic interaction theory to analyze the current situation and characteristics of Guangxi Miao batik communication on Douyin.
Results-Miao batik has a lot of content and characters that can be developed and shared in Chinese social media (Douyin). Batik culture communication has achieved certain results under social media by the government, the media, and many individuals. However, there are still many problems, such as the lack of application of new media technology, the need to improve and innovate content quality, and the lack of combination of Miao batik communication and market development. To create representative social media works that spread Guangxi Miao batik, we must be good at using new media technology, while improving the quality of communication content and realizing the combination of batik communication and e-commerce.
Practical implications-This study promotes the introduction of batik products to the market as special tourist souvenirs, and integrates them with fashion design, home design, cultural and creative peripherals and other fields. This study puts forward some suggestions to further improve the dissemination of Guangxi Miao batik on Chinese social media (Douyin) and promote the protection and inheritance of batik craftsmanship.
Towards a Greek Proverb Atlas: A Computational Spatial Exploration and Attribution of Greek Proverbs
Authors: Pavlopoulos John , Louridas Panos , Filos Panagiotis 
Published: October 2024

Abstract

Proverbs carry wisdom transferred orally fromgeneration to generation. Based on the placethey were recorded, this study introducesa publicly-available and machine-actionabledataset of more than one hundred thousandGreek proverb variants. By quantifying thespatial distribution of proverbs, we show thatthe most widespread proverbs come from themainland while the least widespread proverbscome primarily from the islands. By focusingon the least dispersed proverbs, we present themost frequent tokens per location and under-take a benchmark in geographical attribution,using text classification and regression (textgeocoding). Our results show that this is a chal-lenging task for which specific locations can beattributed more successfully compared to oth-ers. The potential of our resource and bench-mark is showcased by two novel applications.First, we extracted terms moving the regressionprediction toward the four cardinal directions.Second, we leveraged conformal prediction toattribute 3,676 unregistered proverbs with sta-tistically rigorous predictions of locations eachof these proverbs was possibly registered in.
Effects of Different AI-driven Chatbot Feedback on Learning Outcomes and Brain Activity
Authors: Hu Yi , Yin Jiaqi , Xu Haoxin , Pan Yafeng 
Published: October 2024

Abstract

Artificial intelligence (AI)-driven chatbots provide instant feedback to support learning. Yet, the impacts of different feedback on behavior and brain activation remain underexplored. We investigated how metacognitive, affective, and neutral feedback from an educational chatbot affected learning outcomes and brain activity through functional near-infrared spectroscopy technique. Students receiving metacognitive feedback showed higher transfer scores and metacognitive sensitivity, brain activation in the frontopolar area and middle temporal gyrus than other feedback types. Such activation correlated with metacognitive sensitivity. Students receiving affective feedback showed better retention scores than those receiving neutral feedback and higher activation in the supramarginal gyrus. Students receiving neutral feedback exhibited higher activation in the frontal eye fields and dorsolateral prefrontal cortex than other feedback types. The machine learning model outputs key brain regions that predict transfer scores. These findings underscore the potential of diverse feedback types in enhancing learning via human-chatbot interaction.
PCSK-9 inhibitors improve cardiovascular events after PCI in patients with chronic kidney disease
Authors: xu hao , Li Jian 
Published: October 2024

Abstract

Objective:
To investigate the correlation between Lp(a) levels and the degree of coronary artery stenosis in patients with coronary artery disease (CAD) complicated with chronic kidney disease (CKD); evaluate the predictive value of Lp(a) in patients with CAD complicated with CKD; and evaluate the clinical value of PCSK-9 inhibitors in patients with CAD complicated with CKD.
Method:
A total of 494 patients admitted to our hospital for coronary angiography from October 2017 to December 2019 were included in this study. The patients were divided into a CKD group (n = 247) and a non-CKD group (n = 247). The CKD patients were divided into 3 groups according to the glomerular filtration rate (eGFR). The Gensini score was used to evaluate the coronary plaque load. Changes in the blood lipid index and its correlation with the coronary Gensini score were analyzed. CAD patients with CKD who received PCI were further divided into a PCSK-9 inhibitor treatment group and a conventional treatment group to explore the lipid-lowering effect of a PCSK-9 inhibitor on major adverse cardiac events (MACEs)(cardiac death, nonfatal myocardial infarction, heart failure and angina readmissions).
Result:
The levels of TG and Lp(a) in the CKD group were greater than those in the non-CAD combined CKD group (P < 0.05). The HDL-C level in the CAD combined with CKD group was lower than that in the non-CAD combined with CKD group (P < 0.05). However, there were no significant differences in TC or HDL-C levels between the two groups (P > 0.05). Lp(a) was significantly positively correlated with the coronary Gensini score (r = 0.135, P < 0.05), and this correlation was observed only in the moderate renal insufficiency group (r = 0.222, P < 0.05). PCSK-9 inhibitors significantly reduced LDL-D (-30.28% vs. -4.44%, P = 0.000) and Lp(a) levels (-25.22% vs. -10%, P = 0.006) in patients with CKD. In addition, PCSK-9 inhibitors reduced the occurrence of MACEs in patients (HR: 0.27, 95% CI 0.07–0.99; P = 0.013).
Conclusion:
In CAD patients with CKD, the degree of coronary stenosis becomes increasingly severe with increasing Lp(a) levels, and the Lp(a) level can be used as a predictor of the degree of coronary stenosis in CAD patients with CKD. PCSK-9 inhibitors reduce the incidence of cardiovascular events in patients with CKD.
Artificial light at night and temperature as combined stressors on the development, life-history, and mating behaviour of the Pacific field cricket, Teleogryllus oceanicus
Authors: McNamara Kathryn , Fitzgerald Nicholas , Kim Zion , Rutkowski Nicola-Anne , Jones Theresa 
Published: October 2024

Abstract

Unprecedented rates of urbanisation cause detrimental impacts on the natural environment. Two of the most prominent and ubiquitous urban stressors are artificial light at night (ALAN) and the urban heat island (UHI) effect. Individually, these two stressors have a wide array of effects on physiological, behavioural, and life-history traits of organisms. However, stressors rarely work in isolation, and the potential interactions of ALAN and elevated temperatures on organismal life-history traits, particularly with respect to sexual signalling and reproduction, are not well understood. Here, in a fully factorial design, we manipulated intensities of ALAN exposure (simulating urban light pollution) and/or developmental rearing temperatures (simulating UHI effects) to explore the consequences for juvenile development, survival, sexual signalling, and mating behaviour of the Pacific field cricket, Teleogryllus oceanicus. Our data revealed significant effects of temperature on key life-history traits. Crickets reared under elevated temperatures had higher mortality; reduced adult longevity, altered sexual signalling and male attractiveness. In isolation, ALAN had very limited impacts, reducing male juvenile development time. Similarly, both stressors acting in concert also had little impact; ALAN reduced female developmental duration when reared at control temperatures, but not elevated temperatures. These data suggest very limited effects of combined stressors in this species, while elevated temperatures, consistent with urban heat island effects, had equivocal effects on life-history traits, reducing survival, but potentially increasing male fitness. Our data highlight the complexity of urban stressors on wildlife behaviour and fitness. Understanding these processes is essential as both ALAN and temperature are predicted to intensify.
A spontaneous anterior fusion of lumbar spine after posterolateral lumbar fusion with pedicle screw-plate system
Authors: Kraiwattanapong Chaiwat , Chandrsawang Issara , Keorochana Gun , Rajinda Panupol , Chanplakorn Pongsthorn , Leelapattana Pittavat , Udomsubpayakul Umaporn , Lertudomphonwanit Thamrong 
Published: October 2024

Abstract

Background
Lumbar posterolateral fusion (PLF) with Pedicle Screw-Plate (PSP) fixation without interbody fusion found spontaneous anterior fusion (SAF). No study has reported the SAF of lumbar spine in patients who underwent PLF. This study reports the rate of SAF of lumbar spine after PLF with PSP system compared with the rate of SAF after PLF with pedicle screw-rod (PSR) system.
Methods
Retrospective reviews of charts and radiographs were performed in 111 patients who underwent PLF with PSP system and PSR system for treatment of degenerative lumbar spine. Demographic data, diagnosis, Myerding grading, level of fusion, Pfirmann grading, disc height, pedicle screw depth, follow up time and SAF were compared between PSP and PSR groups.
Results
Fifty-five patients in the PSP group and 56 patients in the PSR group were included with similar baseline characteristics. There were more degenerative spondylolisthesis patients in the PSP group compared with patients in the PSR group. However, there was no significant difference of Pfirmann grading in both groups. Fifteen patients (27.3%) in the PSP group developed SAF while no patient in the PSR group had SAF. When patients in the PSP group were analyzed, the mean follow-up time in patients with SAF was significantly longer than the no SAF group.
Conclusion
This study has reported SAF of lumbar spine in patients who underwent PLF with the PSP system. The SAF increasingly occurred with longer follow-up time. In this study, no SAF was found in patients who underwent PLF with the PSR system.
Exposure to air pollutants and breast cancer risk: mediating effects of metabolic health biomarkers in a nested case-control study within the E3N-Generations cohort
Authors: Mercoeur Benoît , Fervers Béatrice , Coudon Thomas , Noh Hwayoung , Giampiccolo Camille , Grassot Lény , Faure Elodie , Couvidat Florian , Severi Gianluca , Mancini Francesca Romana , Roy Pascal , Praud Delphine , Amadou Amina 
Published: October 2024

Abstract

Background Growing epidemiological evidence suggests an association between exposure to air pollutants and breast cancer. Yet, the underlying mechanisms remain poorly understood. This study explored the mediating role of thirteen metabolic health biomarkers in the relationship between exposure to three air pollutants, i.e. nitrogen dioxide (NO2), polychlorinated biphenyls 153 (PCB153), and benzo[a]pyrène (BaP), and breast cancer risk.Methods We used data from a nested case-control study within the French national prospective E3N-Generations cohort, involving 523 breast cancer cases and 523 matched controls. The four-way decomposition mediation of total effects for thirteen biomarkers was applied to estimate interaction and mediation effects (controlled direct, reference interaction, mediated interaction, and pure indirect effects).Results The analyses indicated a significant increase in breast cancer risk associated with BaP exposure (odds ratio (OR)Q4vsQ1 = 2.44, 95% confidence intervals (CI): 1.05–5.68). PCB153 exposure showed a statistically significant association only in the third quartile (ORQ3vsQ1 = 2.33, CI: 1.13–4.84), but it appeared to be non-significant and slightly attenuated in the highest quartile (ORQ4vsQ1 = 2.11, CI: 0.93–4.78). No significant association was observed between NO2 exposure and breast cancer risk. Estradiol was associated with an increased risk of breast cancer (OR per one standard deviation (SD) increase = 1.22, CI: 0.05–1.42), while thyroid-stimulating hormone was inversely related to breast cancer risk (OR per 1SD increase = 0.87, CI: 0.75-1.00). A non-statistically significant mediated effect of the association between the three pollutants and breast cancer risk, through albumin, high-density lipoproteins cholesterol, low-density lipoprotein cholesterol, parathormone, and estradiol was suggested.Conclusion Although limited by a lack of statistical power, this study provides relevant insights into the potential mediating role of certain biomarkers in the association between air pollutant exposure and breast cancer risk, highlighting the need for further in-depth studies in large populations.
Leveraging Social Media for Academic Success in Nursing Education
Authors: Erden Yasemin , Kahraman Handan Aydın , Çiftçi Bahar 
Published: October 2024

Abstract

Aim: This study evaluated the impact of social media-supported learning on nursing students' academic achievement and social media use.
Method: Parenteral drug administration was taught interactively for 12 hours. Skills were demonstrated in a 24-hour lab session. An Instagram page provided educational videos and images for four weeks, with daily Q&A in the story section. Post-training, students completed evaluation forms.
Results: The intervention group showed a significant improvement in post-test scores compared to the control group (p<0.001). Exam scores post-training were significantly higher than pre-training (p<0.001).
Conclusion: Social media-supported learning positively affects academic achievement and engagement in nursing education.
Study on the preparation of calcium modified coal gangue and its adsorption performance of phosphate
Authors: Dong Yanrong , Gao Ziqing , Zhai Hongyu , Gong Guohao , Li Fengjuan 
Published: October 2024

Abstract

Excessive phosphate in water leads to eutrophication, and to address this, a new calcium-modified coal gangue (CaMCG) was developed using coal gangue and calcium chloride for phosphate removal. The optimum preparation conditions of CaMCG were obtained by response surface test: mcalcium chloride:mcoal gangue=1, calcination temperature 735℃, calcination time 135 min. Batch adsorption experiments showed that when the phosphate concentration was 100 mg/L, the optimal CaMCG dosage was 0.5 g and the optimal reaction time was 48 h. At pH 3-7, the adsorption capacity of CaMCG for phosphate was always good. The order of the strength of coexisting anions affecting the adsorption of phosphate by CaMCG was: CO32- > SO42- > HCO3- > NO3- ≈ Cl-. Kinetic isotherm analysis showed that the adsorption of phosphate by CaMCG had both physical adsorption and chemical adsorption. The theoretical maximum adsorption capacity of CaMCG for phosphate was 17.85 mg/g. The adsorption process of CaMCG on phosphate conformed to the Langmuir model. The main mechanisms of CaMCG adsorbing phosphate are surface precipitation, adsorption exchange and complexation. This study shows that CaMCG has great potential in adsorbing phosphate, which can provide technical reference for the efficient utilization of coal gangue and the treatment of phosphate wastewater.