bluuebunny/crossref_metadata_2025_split huggingface dataset:
El problema de la finalidad en la naturaleza
Authors: Rodríguez Prieto Sylvia Susana 
Published: January 2018

El Juicio de gusto como Juicio estético parte de la contemplación de un objeto en particular. Surge de forma libre y no guarda relación alguna con una intencionalidad por parte del sujeto. En el caso de un juicio sobre lo bello se considera que atribuye cierta belleza al objeto como si se tratase de una propiedad que le caracteriza. La forma en la que se da este juicio posibilita el surgimiento de cierta universalidad del mismo en la medida en que todo aquel que pueda contemplarlo pueda distinguir la belleza en él. Pero se trata sólo de universalidad estética y no lógica. En la forma que adoptan estos objetos se advierte una finalidad de la naturaleza como condición a priori que posibilita su conocimiento. Dicha posibilidad basada en la reflexión sobre la forma de estos viene determinada por el uso reflexionante de la facultad de juzgar.
Nietzsche en las vanguardias
Authors: De la Fuente Teixidó Ana María 
Published: January 2018

Las vanguardias artísticas nacieron insertas en un mundo de cambios para destronar un sistema de órdenes que estaban en decadencia. En los inicios del XX se experimentó la primera gran crisis del canon estético que hasta entonces definía el arte, los vanguardistas lo cuestionaron provocando la ruptura del discurso narrativo tradicional y lo reinventaron hasta convertirlo en uno de los pilares del mundo contemporáneo, abriendo una puerta desde lo imposible a lo posible. Como se verá en este artículo, debido a su sentido crítico, la obra de Nietzsche fue capaz de anticipar las coordenadas generales de las vanguardias con los ejes de su pensamiento: el nihilismo, la dicotomía dionisiaca/apolínea y la voluntad de poder como conceptos clave para comprender su génesis, el proceso de acción artística y su sentido. Para ello se recorrerá su obra en sus distintas etapas, y se interrelacionarán con las vanguardias, especialmente con el dadaísmo y el surrealismo.
Estética de la existencia y educación: la innovación pedagógica de finales del s.XX
Authors: Roldán López Carlos 
Published: January 2018

Las prácticas educativas están social, político e históricamente construidas. Se construyen modelos y rituales en las prácticas educativas y se reproducen constantemente, haciendo perpetuar los elementos culturales y políticos introduciéndolos en los sujetos. Son dispositivos de poder. A su vez, son prácticas construidas desde lo singular, es decir que se estructura desde cada actor de la práctica aportándole su propia significación. Así, la práctica educativa está inserta en múltiples significaciones. En este sentido, la docencia puede entenderse como un mecanismo de resistencia ante los dispositivos de poder, cuando se enmarca dentro del contexto más amplio de los llamados “cura sui” o Estéticas de la existencia concebidos por Michel Foucault.
MRI and 11C acetate PET/CT for prediction of regional lymph node metastasis in newly diagnosed prostate cancer
Authors: Below Catrin von , Wassberg Cecilia , Grzegorek Rafael , Kullberg Joel , Gestblom Charlotta , Sörensen Jens , Waldén Mauritz , Ahlström Håkan 
Published: January 2018

Abstract

Background
The aim of the study was to examine the value of quantitative and qualitative MRI and 11C acetate PET/CT parameters in predicting regional lymph node (LN) metastasis of newly diagnosed prostate cancer (PCa).

Patients and methods
Patients with intermediate (n = 6) and high risk (n = 47) PCa underwent 3T MRI (40 patients) and 11C acetate PET/CT (53 patients) before extended pelvic LN dissection. For each patient the visually most suspicious LN was assessed for mean apparent diffusion coefficient (ADCmean), maximal standardized uptake value (SUVmax), size and shape and the primary tumour for T stage on MRI and ADCmean and SUVmax in the index lesion. The variables were analysed in simple and multiple logistic regression analysis.

Results
All variables, except ADCmean and SUVmax of the primary tumor, were independent predictors of LN metastasis. In multiple logistic regression analysis the best model was ADCmean in combintion with MRI T-stage where both were independent predictors of LN metastasis, this combination had an AUC of 0.81 which was higher than the AUC of 0.65 for LN ADCmean alone and the AUC of 0.69 for MRI T-stage alone.

Conclusions
Several quantitative and qualitative imaging parameters are predictive of regional LN metastasis in PCa. The combination of ADCmean in lymph nodes and T-stage on MRI was the best model in multiple logistic regression with increased predictive value compared to lymph node ADCmean and T-stage on MRI alone.
Ocular changes in metastatic melanoma patients treated with MEK inhibitor cobimetinib and BRAF inhibitor vemurafenib
Authors: Gavric Ana Ursula , Ocvirk Janja , Mekjavic Polona Jaki 
Published: January 2018

Abstract

Background
Mitogen-activated protein kinase kinase (MEK) inhibitor cobimetinib and V-raf murine sarcoma viral oncogene homolog B1 (BRAF) inhibitor vemurafenib have significantly improved the prognosis of BRAF-mutated metastatic melanoma. Some ocular symptoms and signs were recently recognized to follow this treatment. The study was aimed to investigate ocular toxicity in patients with metastatic melanoma treated with cobimetinib in combination with vemurafenib.

Patients and methods
In the prospective, observational study, patients with BRAF-mutated metastatic melanoma treated with cobimetinib in combination with vemurafenib at the Institute of Oncology Ljubljana were asked to participate. Ophthalmic examination was performed including measurement of visual acuity and intraocular pressure, slit lamp examination, funduscopy (CF), infrared-reflectance (IR) imaging and optical coherence tomography (OCT).

Results
Five out of 7 patients noticed changes in vision few days after starting the therapy with cobimetinib. In all patients, small circular lesions, described as MEKAR lesions, were documented in outer retinal layers demonstrated with OCT, IR, and CF. Changes were in the center and/or scattered over the retina almost symmetrical in both eyes in 6 patients, and asymmetrical in one patient, the latter presented also with unilateral anterior uveitis and cystoid macular edema.

Conclusions
Multiple bilateral foveal and extrafoveal small retinal lesions in the outer retinal layers develop in patients treated with MEK inhibitor in combination with BRAF inhibitor. Ophthalmologists and oncologists need to be aware of this common, yet relatively benign and often transient ocular side effect to avoid needless intervention, including the discontinuance of a potentially life-prolonging therapy.
Sclerosing melanocytic lesions (sclerosing melanomas with nevoid features and sclerosing nevi with pseudomelanomatous features) – an analysis of 90 lesions
Authors: Grcar-Kuzmanov Biljana , Bostjancic Emanuela , Bandres Juan Antonio Contreras , Pizem Joze 
Published: January 2018

Abstract

Background
Sclerosing melanocytic lesions, which are characterized by either focal or diffuse sclerosis in the dermal component and atypical proliferation of predominantly nevoid melanocytes, remain poorly defined. Our aim was to analyze systematically their morphologic spectrum, especially the distinction between sclerosing melanocytic nevus and sclerosing melanoma, which has not been well documented.

Patients and methods
We collected 90 sclerosing melanocytic lesions, occurring in 82 patients (49 male, 33 female; age range from 21 to 89 years). A four probe fluorescent in situ hybridization (FISH) assay was performed in 41 lesions to substantiate the diagnosis of sclerosing melanomas.

Results
A prominent full-thickness pagetoid spread of melanocytes was identified in 44 (48%) lesions, and a melanoma in situ adjacent to the sclerosis in 55 (61%) lesions. In the intrasclerotic component, maturation was absent in 40 (44%) and mitotic figures were identified in 18 (20%) lesions. Of the 90 lesions, 26 (29%) were diagnosed morphologically as nevi and 64 (71%) as melanomas (Breslow thickness from 0.4 to 1.8 mm), including 45 (50%) melanomas with an adjacent nevus. A four-probe FISH assay was positive in the sclerotic component in 14 of 25 lesions diagnosed morphologically as melanomas and none of 16 nevi. A sentinel lymph node biopsy was performed for 17 lesions and was negative in all cases.

Conclusions
Sclerosing melanocytic lesions form a morphologic spectrum and include both nevi and melanomas. The pathogenesis of sclerosis remains obscure but seems to be induced by melanocytes or an unusual host response in at least a subset of lesions.
A constituição do Centro de Preservação da História Ferroviária do Rio Grande do Sul de Oitenta
Authors: Lewinski Cinara Isolde Koch 
Published: January 2018

Este artigo tem por objetivo debater um tema ligado ao patrimônio histórico e surgiu da necessidade de se desenvolver um estudo sobre a atuação do Programa de Preservação do Patrimônio Histórico no Rio Grande do Sul, a partir das carências constatadas através da investigação sobre o assunto. Por isso, o Museu do Trem, antiga Estação Ferroviária de São Leopoldo, se tornou o objeto de pesquisa, pois, abrigou o Centro de Preservação da História Ferroviária do nosso Estado. A metodologia sobre o estudo está concentrada na pesquisa documental, com a finalidade de investigar a reconstituição histórica do Preserve/fe em nosso Estado, na década de 1980. A pesquisa que está sendo elaborada é embasada teoricamente na história cultural e consiste em demonstrar a importância de se fazer um estudo mais aprofundado sobre a iniciativa do Governo Federal em preservar o patrimônio ferroviário do Rio Grande do Sul. Portanto, este artigo tem a pretensão de discorrer sobre composição do patrimônio ferroviário gaúcho por meio de uma breve análise sobre os motivos que levaram à construção de seu acervo utilizando-se de critérios para seleção dos objetos que perderam as suas atribuições funcionais e passaram a ser ressignificados como patrimônio.
GLOBALIZACÃO, SISTEMA JURÍDICO E MUNDANCAS SOCIAIS NA AMERICA LATINA: UM LONGO CAMINHO A PERCORRER
Authors: Cademartori Sergio , Miranda José 
Published: January 2018

O sistema jurídico Latino Americano enfrentou processos de reforma e transformação substanciais nos últimos 15 anos. Os desafios políticos e sociais da democratização e da globalização têm afetado esse sistema jurídico de diferentes maneiras. A democratização e os processos neoliberais não foram suficientes para superar a situação de injustiça social. No contexto atual da América Latina, é provável que a implementação do Estado de Direito faça uma diferença significativa em termos das políticas que poderiam ser defendidas. Este estudo analisa os principais desafios para a sociedade latino-americana alcançar um sistema legal mais democrático e justo nos últimos 15 anos.
Pengaruh Model Pembelajaran Berbasis Masalah dan Ekspositori dengan Keterampilan Proses Sains Terhadap Hasil Belajar Fisika Siswa Kelas VIII MTsN 1 Mataram Tahun Ajaran 2014/2015
Authors: Hardiyanto Hardiyanto , Susilawati Susilawati , Harjono Ahmad 
Published: January 2018

This research aims to (1) reveal the effect of problem based and expository learning towards physicsÃ¢â¬â¢ learning outcomes, (2) uncover the effect of studentsÃ¢â¬â¢ science process skill towards physicsÃ¢â¬â¢ learning outcomes, (3) reveal the interaction between studentsÃ¢â¬â¢ science process skill and their physicsÃ¢â¬â¢ learning outcomes. This study is a quasi-experimental study applying factorial design 2 x 2. The study was conducted from November 2014 to May 2015.ÃÂ The population of this research is the whole students of class VIII which comprises of 9 classes in MTS Negeri 1 Mataram. The purposive sampling was chosen as the sampling technique for this study, in which class VIII-8 acted as the experiment class and class VIII-7 as the controlled class. The data collection encompasses data of science process skill, and studentsÃ¢â¬â¢ physicsÃ¢â¬â¢ learning outcomes (in the cognitive, affective, and psychomotor domains) towards the main material of light. Technique of collecting data of science process and physicsÃ¢â¬â¢ learning outcomes in affective and psychomotor domains were done by using observation sheet with certain criteria, while cognitive domain was done through the test.ÃÂ The test instrument has previously been through validity test, reliability test, difficulty level, and discrimination index. The data obtained were firstly tested their normality and homogeneity, then continued by the testing of the hypothesis by using two-way analysis of variance (ANOVA). Data analysis technique was done by using ANOVA 2x2 with different cell. The result of this study shows that (1) problem based and expository learning affects physicsÃ¢â¬â¢ learning outcomes, (2) studentsÃ¢â¬â¢ science process skill affects their physicsÃ¢â¬â¢ learning outcomes, and (3) there is no interaction between science process skill and studentsÃ¢â¬â¢ learning outcomes.
Pengaruh Model Project Based Learning Berbantuan Media Virtual Terhadap Penguasaan Konsep Peserta didik pada Materi Alat-alat Optik
Authors: Suranti Ni Made Yeni , Gunawan Gunawan , Sahidu Hairunnisyah 
Published: January 2018

Learning physics should be able to provide an understanding physics of abstract concepts. One of the efforts being made to improve the learning of Physics is to use appropriate learning model. This study aims to improve the studentÃ¢â¬â¢s conceptual understanding by using project based learning model with virtual media for X Grade student at SMAN 2 Mataram Years 2015/2016. This study was conducted using a type of quasi-experimental research, untreated control group design with pretest and posttest on Optic. Hypothesis test results that the model used to give effect to theÃÂ studentÃ¢â¬â¢s conceptual understanding, was shown to increase student conceptual understanding was higher in the experimental class compared with the control class. N-gain test results stating that the conceptual understanding has increased in each sub material. The results of the analysis conceptual understanding score on every aspect of cognitive increased.ÃÂ
Pengaruh Model Pembelajaran Berbasis Masalah Berbantuan Simulasi Virtual Terhadap Penguasaan Konsep dan Kreativitas Fisika Siswa SMAN 2 Mataram
Authors: Dewi Shinta Mutiara , Harjono Ahmad , Gunawan Gunawan 
Published: January 2018

This research is a quasi-experimental aims to identify the effect of problem-based learning model using virtual simulation media towards the studentsÃ¢â¬â¢ concept mastery and creativity in physics. The design of this research used of non-equivalent control group design, while the sampling technique used purposive sampling. The population of this research is all students of grade X SMAN 2 Mataram, while the sampling are the students of grade X-3 as the experimental group and the students of grade X-4 as control group. The data obtained in this research isÃÂ data mastery of concept and creativity. The research hypothesis was tested using t-test polled variances. The test result showed that the N-gain mastery of concepts has increased in each sub material and the highest increase in the sub matter theory of electromagnetic waves. Values of N-gain experimental group in the high category (71%) and control group in the medium category (53%). T-test showed that the model is applied to significant influence on improving studentsÃ¢â¬â¢ mastery of concepts and creativity, higher in the experimental group compared with the control group. Increased figural creativity higher than verbal creativity in both classes
Pengaruh Model PBL Berbantuan Media Virtual Tehadap Kemampuan Pemecahan Masalah Fisika
Authors: Hastuti Andriyani , Sahidu Hairunnisyah , Gunawan Gunawan 
Published: January 2018

This study aims to determine the effect model of Problem Based Learning (PBL) aided virtual media to the mastery of the concepts of physics students SMK 1 Lingsar Academic Year 2015/2016. This study is a quasi-experimental design with Nonequivalent Control Group Design. The study population all students of class X SMK 1 Lingsar and research sample class X-1 and X MM MM-3 were selected by purposive sampling. Data analysis using polled variance t test. The results showed that the model PBL-aided virtual media influence on students' mastery of concepts of physics. Judging from the average value, penguasaam concepts of physics experimental class is higher than the control class. N-gain first test showed that an increase in the value of the mastery of the concept of the experimental class to the theory and calculation.ÃÂ N-gain second Test results show that the experimental group was higher than the control class in each sub material unless the material collision
Pengaruh Model Direct Instruction Berbantuan Simulasi Virtual Terhadap Penguasaan Konsep Siswa
Authors: Arianti Baiq Ida , Sahidu Hairunnisyah , Harjono Ahmad , Gunawan Gunawan 
Published: January 2018

Penelitian ini merupakan jenis penelitian quasi eksperimen dengan desain non-equivalent control grup design. Pengambilan sampel dilakukan dengan teknik purposive sampling. Populasi penelitian adalah seluruh siswa kelas X MIA MAN 2 Praya. Sampel penelitian diperoleh siswa kelas X MIA-1 sebagai kelas eksperimen dan siswa kelas X MIA-2 sebagai kelas kontrol. Data penelitian dianalisis dengan uji-t polled varians dengan taraf signifikan 5%, dan diperoleh hasil thitung =2,54ÃÂ dan ttabel = 2,02. Oleh karena thitung >ttabel, maka dapat disimpulkan bahwa model direct instruction berbantuan simulasi virtual berpengaruh terhadap penguasaan konsep fisika siswa
Pengaruh Penggunaan Media Audiovisual Dengan Pendekatan Metakognitif Berbasis Masalah Terhadap Hasil Belajar Fisika Siswa Kelas XI IPA Di SMAN 1 Gerung Tahun Pelajaran 2016/2017
Authors: Prayudi Lalu M. Eka , Sahidu Hairunnisyah , Gunawan Gunawan 
Published: January 2018

The purpose of this study is to examine the effect of audiovisual media with problem based metacognitive approach toward physics learning result of XI IPA at SMAN 1. The type of the study is experimental by using pretest-post test control group design. The population are XI IPA 1st semester students is 299. The technique that used to collect the sample is cluster random sampling, XI IPA 3 students as experiment class and XI IPA 4 students as controll class and each consist of 34 students. The media that used as audiovisual is powerpoint. Instrument that used is multiple choices consist of 20 question. The learning result of experiment class students and control class each 70.15 and 61.85. ÃÂ score experiment class and control class obtained consecutively 12.5086 and 12.9889, ÃÂ score is 15, so that both of class distibuted normally. Fcount ÃÂ score obtained 1.00 < FtabelÃÂ is 1.77 so that both of sample class is homogen. The data result analysis by using T-test onÃÂ both class by significant 5% and Tcount ÃÂ obtained is 2.45 and Ttabel ÃÂ is 1.99 on db 66, it means that Ho rejected and Ha accepted, so that it can be concluded there is an efffect of using audio visual media with metacognitive based on problem toward physics learning result of XI IPA at SMAN 1 Gerung accademic year 2016/2017.
Pengaruh Penggunaan Laboratoium Virtual Dalam Pembelajaran Inkuiri Terbimbing Terhadap Penguasaan Konsep Kalor Peserta Didik
Authors: Hermansyah Hermansyah , Gunawan Gunawan , Harjono Ahmad 
Published: January 2018

The purpose of this study is to examine the effect of using virtual laboratory in guided inquiry learning on studentsÃ¢â¬â¢ mastery concept of heat material.ÃÂ This study is quasi experiments with posttest only control group design. There were 58 respondents in this study which were divided into two group; experimental group and control group. The data were analyzed by using t-test. The results showed that experimental groupsÃ¢â¬â¢ mastery concepts significantly differed from the control group. It can be concluded that the use of virtual laboratory in guided inquiry learning model affects studentsÃ¢â¬â¢ mastery concepts of heat material.
Sintesis Dan Karakterisasi Sifat Optik Polimer Film PVA-TCA-MB
Authors: `Ardhuha Jannatin , Verawati Ni Nyoman Sri Putu , Taufik Muhammad , Ayub Syahrial 
Published: January 2018

Polyvinyl alcohol (PVA) based film polymers that contain trichloroacetic acid (TCA) and methylene blue (MB) dye has been synthesized. The synthesis aimed to obtain material that can be applied as film dosimeter. Six PVA-TCA-MB thin film samples have been synthsized by varying PVA grades and TCA composition. Characterization of optical property of the resulted polymer was undertaken by measuring samples absorption within wavelength range of 200 nm to 700 nm.ÃÂ Absorption spectrum of samples showed an optimum between 547-644 nm that corresponds to purple colour and characteristic to MB absoption. Further analysis showed the influence of TCA concentration and storage periode of the polymer. Optimization of syntesis by evaluating synthesis condition, heating and storage time is yet to be done in order to obtain polymer that can be used as dosimeter with reproducible optical property.
Software Atom: An approach towards software components structuring to improve reusability
Authors: Mughal Muhammad Hussain , Shaikh Zubair Ahmed 
Published: January 2018

Diversity of application domain compelled to design sustainable classification scheme for significantly amassing software repository. The atomic reusable software components are articulated to improve the software component reusability in volatile industry. Numerous approaches of software classification have been proposed over past decades. Each approach has some limitations related to coupling and cohesion. In this paper, we proposed a novel approach by constituting the software based on radical functionalities to improve software reusability. We analyze the element's semantics in Periodic Table used in chemistry to design our classification approach, and present this approach using tree-based classification to curtail software repository search space complexity and further refined based on semantic search techniques. We developed a Global unique Identifier (GUID) for indexing the functions and related components. We have exploited the correlation between chemistry element and software elements to simulate one to one mapping between them. Our approach is inspired from sustainability chemical periodic table. We have proposed software periodic table (SPT) representing atomic software components extracted from real application software. Based on SPT classified repository tree parsing & extraction to enable the user to program their software by customizing the ingredients of software requirements. The classified repository of software ingredients assist user to exploits their requirements to software engineer and enable requirement engineer to develop a rapid large-scale prototype with great essence. Furthermore, we would predict the usability of the categorized repository based on feedback of users. The continuous evolution of that proposed repository will be fine-tuned based on utilization and SPT would be gradually optimized by ant colony optimization techniques. Succinctly would provoke automating the software development process.