bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age Increases Monocyte Adhesion on Collagen
Authors: Khalaji Samira , Zondler Lisa , KleinJan Fenneke , Nolte Ulla , Mulaw Medhanie A. , Danzer Karin M. , Weishaupt Jochen H. , Gottschalk Kay-E. 
Published: May 2017

AbstractAdhesion of monocytes to micro-injuries on arterial walls is an important early step in the occurrence and development of degenerative atherosclerotic lesions. At these injuries, collagen is exposed to the blood stream. We are interested whether age influences monocyte adhesion to collagen under flow, and hence influences the susceptibility to arteriosclerotic lesions. Therefore, we studied adhesion and rolling of human peripheral blood monocytes from old and young individuals on collagen type I coated surface under shear flow. We find that firm adhesion of monocytes to collagen type I is elevated in old individuals. Pre-stimulation by lipopolysaccharide increases the firm adhesion of monocytes homogeneously in older individuals, but heterogeneously in young individuals. Blocking integrin αx showed that adhesion of monocytes to collagen type I is specific to the main collagen binding integrin αxβ2. Surprisingly, we find no significant age-dependent difference in gene expression of integrin αx or integrin β2. However, if all integrins are activated from the outside, no differences exist between the age groups. Altered integrin activation therefore causes the increased adhesion. Our results show that the basal increase in integrin activation in monocytes from old individuals increases monocyte adhesion to collagen and therefore the risk for arteriosclerotic plaques.
Pressure-induced ionic liquid crystal in 1-dodecyl-3-methylimidazolium tetrafluoroborate
Authors: Zhu Xiang , Li Haining , Wang Zheng , Yuan Chaosheng , Zhu Pinwen , Su Lei , Yang Kun , Wu Jie , Yang Guoqiang , Li Xiaodong 
Published: May 2017

The phase behaviors of 1-dodecyl-3-methylimidazolium tetrafluoroborate ([C12MIM][BF4]) had been investigated by means of Raman spectroscopy and polarized optical microscopy under pressure values up to 2.0 GPa at the temperature of 80.0 °C.
The Trifocus Framework and Interprofessional Collaborative Practice in Severe Disabilities
Authors: Bruce Susan M. , Bashinski Susan M. 
Published: May 2017

Purpose
Individuals with severe disabilities are a diverse group of learners with complex communication needs. This article presents a synthesis of the literature addressing the five strategies of the trifocus framework, with its triadic structure of learner with disability, communication partner, and environment. The application of interprofessional collaborative practice (IPCP) to the implementation of trifocus framework communication strategies is emphasized.

Method
A literature search was conducted using Google Scholar and EBSCO to identify literature and research studies on IPCP and communication intervention for learners with severe disabilities, published 1994–2015, and then organized within the trifocus framework. The trifocus strategies are enhancing sensitivity, utilizing routines, increasing communication opportunities, modifying the communication environment, and augmenting input. Studies that included at least one participant with severe disabilities and their communication partners were considered. A secondary search was then conducted by reviewing the articles referenced in the original articles.

Conclusion
Effective IPCP in communication intervention considers the learner's characteristics, the knowledge and skills required of communication partners, and effective environmental arrangements to support communication. Future research should include clear participant descriptions, documentation of fidelity measures, and evidence of generalization to support professionals to know when findings are relevant to the individuals they serve.
Effective Team Practices: Interprofessional Contributions to Communication Issues With a Parent's Perspective
Authors: Cooper-Duffy Karena , Eaker Kerri 
Published: May 2017

Purpose
This clinical focus article contains a detailed description of how to build effective teams that use interprofessional collaborative practice (IPCP) with special-education professionals, speech-language pathologists, and families of children with severe disabilities.

Method
This clinical focus article provides information on using the essential elements of team building and IPCP to provide quality care to families who have children with severe disabilities. The 6 essential elements for team building are described, with suggestions for including families in each: goal-setting, roles and responsibilities, effective and efficient process, communication and interpersonal relationships, collaborative problem solving, and evaluation. The 4 competency domains of IPCP are embedded into each of the team-building elements to demonstrate how teams can implement IPCP.

Results
A case study illustrates the difficulty one parent experienced working with a team across the 6 essential team-building elements when seeking communication services for her child with severe disabilities.

Conclusions
Building teams with IPCP can be effective for including families and creating high-quality outcomes for individuals with severe disabilities.
Cotreatment as a Vehicle for Interprofessional Collaborative Practice: Physical Therapists and Speech-Language Pathologists Collaborating in the Care of Children With Severe Disabilities
Authors: Sylvester Lorraine , Ogletree Billy T. , Lunnen Karen 
Published: May 2017

Purpose
This article defines interprofessional collaborative practice and links its key features with accepted practice conceptualizations of physical therapy. Cotreatment with speech-language pathology is described as a vehicle for interprofessional collaborative practice for children with severe disabilities.

Method
The article reviews the International Classification of Functioning, Disability, and Health (WHO, 2015) and the Hypothesis-Oriented Algorithm for Clinicians II (Rothstein, Echternach, & Riddle, 2003) as existing service-delivery frameworks in physical therapy and discusses how interprofessional collaborative practice between speech-language pathologists and physical therapists can be useful within these practice guidelines.

Results
A case illustration featuring interprofessional collaborative practice during cotreatment for a child with severe disabilities through physical therapy and speech-language pathology showed more seamless care and better progress in the pursuit of three main goals: physical movement, communication of needs, and participation in classroom activities.

Conclusions
Interprofessional collaborative practice is supported as a recommended practice methodology for physical therapists and speech-language pathologists serving persons with severe disabilities.
Platelet-Rich Plasma in Reconstruction of Posterior Meatal Wall after Canal Wall Down Mastoidectomy
Authors: Elbary Mohammad El-Sayed Abd , Nasr Wail Fayez , Sorour Samir Sorour 
Published: May 2017

Introduction Canal wall down (CWD) mastoidectomy has many drawbacks, including chronic otorrhea not responding to medications, granulations, dizziness on exposure to cold or hot water, and tendency of debris accumulation in the mastoid cavity, demanding periodic cleaning. Many of these problems can be solved by reconstruction of the posterior meatal wall (PMW).
Objectives To assess the results of PMW reconstruction after CWD mastoidectomy for cholesteatoma using titanium mesh and platelet-rich plasma (PRP) mixed with bone pate.
Methods This study was conducted with 20 patients that have atticoantral chronic suppurative otitis media. All cases were subjected to CWD mastoid surgery with complete elimination of the disease and reconstruction of the PMW by titanium mesh and the mixture of PRP with bone pate. All patients were exposed to a full preoperative evaluation and full postoperative assessment of the complications, the appearance of the external auditory canal contour, and the hearing gain expressed by the change of the air bone gap postoperatively.
Results The PMW reconstructed by titanium mesh and the mixture of PRP with bone pate showed a smooth contour. During the follow-up of 12 to 36 months, the postoperative appearance of the external auditory canal contour was found to be smooth without hidden pouches, irregularities or stenosis in all cases. No granulation, foreign body reaction, or extrusion and/or displacement of the titanium mesh were registered. No facial palsy or recurrent cholesteatoma was reported.
Conclusion The surgical reconstruction of the PMW using PRP, bone pate and titanium mesh after CWD mastoidectomy appears to be reliable without considerable complications, giving a smooth appearance to the PMW.
Short-Term Audiological Results of Diode Laser in Comparison with Manual Perforation in Stapes Surgery
Authors: Hamerschmidt Rogerio , Saab Stephanie , Carvalho Bettina , Carmo Carolina 
Published: May 2017

Introduction Diode laser is a new alternative in stapes surgery for otosclerosis. The present study is the first to compare the short-term results of the surgery performed using diode laser to those obtained through the conventional fenestration technique.
Objective To use audiometry to establish a comparative analysis between the functional results obtained through surgery for otosclerosis using diode laser and the conventional technique.
Method Audiometric evaluation of 12 patients submitted to stapes surgery for otosclerosis, using diode laser or conventional fenestration by needle and drills, between 2014 and 2015. Each group was composed of 6 patients. Pre and post-operative measures were compared for three months in both groups. The speech recognition threshold, the air and bone conduction threshold, as well as the gap between them at 500 Hz, 1 KHz, 2 KHz and 4 KHz were measured.
Results Significant difference in bone conduction and SRT was observed when compared post- and preoperative results in the diode group. However diode and conventional technique groups presented significant differences in air conduction and air-bone gap, suggesting that both can provide functional improvement.
Conclusion Laser stapedotomy is a safe technique with good results. Both laser surgery and the conventional technique have improved the hearing of patients with a discreet advantage for the diode laser. Further prospective and randomized clinical trials are required to disclose all possible benefits of the stapes surgery using diode laser.
The Effects of Prognostic Factors in Idiopathic Sudden Hearing Loss
Authors: Bulğurcu Suphi , Şahin Behçet , Akgül Gökhan , Arslan İlker , Çukurova İbrahim 
Published: May 2017

Introduction Sudden hearing loss is one of the otologic emergencies. The treatment of this disease is affected negatively by some prognostic factors.
Objective In this study, the effects of early treatment initiation in patients with idiopathic sudden hearing loss and of prognostic factors in early treated patients were investigated.
Methods Out of the 216 patients admitted between September 2007 and September 2015, 154 were identified as having idiopathic sudden hearing loss; they were followed-up for a mean time of 7.4 months, and evaluated retrospectively. The effects of several parameters on the success of the treatment were statistically evaluated, such as the time the treatment was initiated, being of the female gender, the severity of the hearing loss, having descending type audiogram patterns, being older than 60 years old, and the co-presence of vertigo.
Results Success rates were found to be significantly higher in idiopathic hearing loss patients that were admitted within the first week (p < 0.05) of the onset of the hearing loss. However, the outcomes were found to be similar when patients admitted within the first 3 days and 4–7 days after the occurrence of the hearing loss were compared (p > 0.05). Parameters such as female gender, severe hearing loss, descending type audiogram, being older than 60 years old, and co-presence of vertigo didn't reveal statistically significant effects on the outcome (p >0.05).
Conclusion The aforementioned prognostic factors, which are well-known in the literature, did not have significant effects when the idiopathic sudden hearing loss treatment was initiated within the first 7 days of the onset of the hearing loss.
Expression and Histopathological Significance of Disabled-2 in Aldosterone-Producing Adenoma
Authors: Li Ping , Zhang Min , Ma Jian-Qiang , Sun Qi , Liu Guang-Xiang , Zhao Xiao-Zhi , Feng Wen-Huan , Shen Shan-Mei , Guo Hong-Qian , Zhu Da-Long 
Published: May 2017

AbstractThe current pathological diagnosis of aldosterone-producing adenoma (APA) is challenging because no histological markers of aldosterone production are available in routine practice. A previous study demonstrated that Disabled-2 (DAB2) is a specific marker of the zona glomerulosa (ZG) in rodents. The aim of the present study was to investigate the significance of immunohistochemical staining to detect DAB2 in the adrenal tissue of patients with APA. We investigated the expression of DAB2 in 36 adrenal glands with APA, 23 adrenal glands with cortisol-producing adenoma (CPA), and 33 adrenal glands with non-functioning adenoma (NFA). Immunohistochemical staining was performed using anti-DAB2 antibodies on paraffin-embedded sections. We analysed the expression of DAB2 semi-quantitatively by scoring staining intensity, and assessed the correlation of this information with the clinical findings. DAB2 mRNA expression in adenoma tissues was evaluated by RT-PCR. DAB2 was highly expressed in the ZG in normal human adrenal glands. DAB2 expression was heterogeneous in APA, with spotted, strong staining noted in most samples (25 of 36 APA). CPA and NFA also exhibited extensive low or moderate DAB2 expression. DAB2 mRNA was significantly increased and positively correlated with CYP11B2 in APA (p<0.05). In APA, the DAB2 score adjusted for tumour volume was positively correlated with plasma aldosterone (p<0.05). Patients with low or moderate DAB2 staining more frequently exhibited high blood pressure and were diagnosed at a younger age compared with patients with high DAB2 staining. The present study clearly demonstrates that DAB2 is a specific marker of the ZG in normal human adrenal glands but that DAB2 immunostaining is not sufficiently powerful for histopathological diagnosis of APA. DAB2 might be involved in excessive aldosterone biosynthesis and correlate with specific clinical characteristics of APA patients.
Iso-duration Determination of D′ and CS under Laboratory and Field Conditions
Authors: Triska Christoph , Karsten Bettina , Nimmerichter Alfred , Tschan Harald 
Published: May 2017

AbstractWhilst Critical Speed (CS) has been successfully translated from the laboratory into the field, this translation is still outstanding for the related maximum running distance (D′). Using iso-duration exhaustive laboratory and field runs, this study investigated the potential interchangeable use of both parameters, D′ and CS. After an incremental exercise test, 10 male participants (age: 24.9±2.1 yrs; height: 180.8±5.8 cm; body mass: 75.3±8.6 kg; V̇ ˙VO2peak 52.9±3.1 mL∙min−1∙kg−1) performed 3 time-to-exhaustion runs on a treadmill followed by 3 exhaustive time-trial runs on a-400 m athletics outdoor track. Field time-trial durations were matched to their respective laboratory time-to-exhaustion runs. D′ and CS were calculated using the inverse-time model (speed=D′/t+CS). Laboratory and field values of D′ and CS were not significantly different (221±7 m vs. 225±72 m; P=0.73 and 3.75±0.36 m∙s−1 vs. 3.77±0.35 m∙s−1, P=0.68), and they were significantly correlated (r=0.86 and 0.94). The 95% LoA were ±75.5 m and ±0.24 m∙s−1 for D′ and CS, respectively. Applying iso-durations provides non-significant differences for D′ and CS and a significant correlation between conditions. This novel translation method can consequently be recommended to coaches and practitioners, however a questionable level of agreement indicates to use D′ with caution.
Neue thixotrope Silikonöle – der Nutzen der Ketchupflasche für die Silikonöltamponade
Authors: Klameth Christian , Kunzmann Berenike , Schultheiß Maximilian , Daniels Rolf , Klameth Nelli , Spitzer Martin 
Published: May 2017

ZusammenfassungSilikonöltamponaden sollen mit einer vernünftigen Geschwindigkeit und unter angemessenen Druckbedingungen ins Auge injiziert und wieder entfernt werden können. Aufgrund immer kleinerer Querschnitte der Inzisionen müssen hochviskose Öle unter zunehmend hohem Druck injiziert und extrahiert werden. Um Problemen, wie längeren Behandlungszeiten oder Hypotonie, begegnen zu können, wurden thixotrope Öle entwickelt. Diese Öle zeichnen sich dadurch aus, dass ihre Viskosität infolge einer kontinuierlichen mechanischen Belastung abnimmt. Solange also Druck oder Sog auf die hier vorgestellten Öle einwirken, werden die Öle dünnflüssiger und fließen deutlich besser. Lässt die mechanische Beanspruchung nach, kehrt die Viskosität zu ihrem ursprünglichen Wert zurück.
Human Epicardial Fat Expresses Glucagon-Like Peptide 1 and 2 Receptors Genes
Authors: Iacobellis Gianluca , Camarena Vladimir , Sant David , Wang Gaofeng 
Published: May 2017

AbstractEpicardial adipose tissue (EAT) is an easily measurable visceral fat of the heart with unique anatomy, functionality, and transcriptome. EAT can serve as a therapeutic target for pharmaceutical agents targeting the fat. Glucagon-like peptide-1 (GLP-1) and GLP-2 analogues are newer drugs showing beneficial cardiovascular and metabolic effects. Whether EAT expresses GLP- 1 and 2 receptors (GLP-1R and GLP-2R) is unknown. RNA-seq analysis and quantitative real-time polymerase chain reaction (qRT-PCR) were performed to evaluate the presence of GLP-1R and GLP-2R in EAT and subcutaneous fat (SAT) obtained from 8 subjects with coronary artery disease and type 2 diabetes mellitus undergoing elective cardiac surgery. Immunofluorescence was also performed on EAT and SAT samples using Mab3f52 against GLP-1R. Our RNA-sequencing (RNA-seq) analysis showed that EAT expresses both GLP-1R and GLP-2R genes. qRT-PCR analysis confirmed that GLP-1R expression was low but detected by 2 different sets of intron-spanning primers. GLP-2R expression was detected in all patients and was found to be 5-fold higher than GLP-1R. The combination of accurately spliced reads from RNA-seq and successful amplification using intron-spanning primers indicates that both GLP-1R and GLP-2R are expressed in EAT. Immunofluorescence clearly showed that GLP-1R is present and more abundant in EAT than SAT. This is the first time that human EAT is found to express both GLP-1R and GLP-2R genes. Pharmacologically targeting EAT may induce beneficial cardiovascular and metabolic effects.
Looplessness in networks is linked to trophic coherence
Authors: Johnson Samuel , Jones Nick S. 
Published: May 2017

SignificanceComplex systems such as cells, brains, or ecosystems are made up of many interconnected elements, each one acting on its neighbors, and sometimes influencing its own state via feedback loops. Certain biological networks have surprisingly few such loops. Although this may be advantageous in various ways, it is not known how feedback is suppressed. We show that trophic coherence, a structural property of ecosystems, is key to the extent of feedback in these as well as in many other systems, including networks related to genes, neurons, metabolites, words, computers, and trading nations. We derive mathematical expressions that provide a benchmark against which to examine empirical data, and conclude that “looplessness” in nature is probably a consequence of trophic coherence.
Translation procedures
Authors: Alwazna Rafat 
Published: May 2017

AbstractTranslation can be seen as a process through which the translator begins with the source text, with an attempt at analyzing this particular text into semantic construction. The translator then reconstructs the semantic construction concerned into proper forms of the target language, seeking to produce an equivalent receptor language text (Larson, 1998: 519). In practice, the translator places himself/herself between the source and target texts, moving from the former to the latter and vice versa. The present paper crucially addresses the stages through which the translator is required to pass in order to achieve an acceptable and appropriate translation. It considers each stage in sufficient detail, showing the significance of these stages for the purpose of achieving a successful translation project. Finally, the present paper argues that the translator has to pass specific steps for the sake of accomplishing an acceptable and appropriate translation and that cognizance of translation theories is crucial in carrying out translation procedures, specifically when adopting the translation strategy on which the whole translation project will generally be based.
La parole poétique de Jean de Breyne dans la traduction croate
Authors: Mikšić Vanda 
Published: May 2017

Résumé
Le livre de poésie C’est quand l’homme parle (2007), de Jean de Breyne, poète français contemporain, condense d´une manière singulière la sonorité, l´oralité et les sensations. La sonorité, étroitement liée à l´oralité, se manifeste tant au niveau superficiel ‒ dans le choix de certains vocables et de leur agencement au niveau syntaxique, qu´au niveau profond, sous-jacent, dans ce qui reste non-dit, tu. L´oralité de la poésie de Jean de Breyne transparaît dans le je et le présent, dans l´hésitation, voire l’auto-correction de son propos, dans l´ellipse, dans la parole suspendue, dans la polyphonie, dans la fréquente bifurcation de ses propos, mais surtout dans le souffle, qui détermine le rythme de son discours poétique. Les sensations que l´énonciateur “présentifie” dans ses vers sont multiples : la vue a une nette prépondérance ‒ ce qui est compréhensible si l´on tient présent le fait que Jean de Breyne fait cohabiter dans sa personne la vocation lyrique avec celle de photographe et celle de critique d´art ‒ mais les autres sens n´en sont nullement exclus. Tenant compte de tous ces éléments, je me propose d´analyser la traduction croate dudit livre de poésie, effectuée par Martina Kramer et moi-même en 2013, en m´appuyant notamment sur des réflexions d´Henri Meschonnic (1970, 1999), d´Antoine Berman (1984, 1999) ainsi que de Jean-Luc Nancy (2001).
Hydrogen redistribution under stress-induced diffusion and corresponding fracture behaviour of a structural steel
Authors: Kan B. , Yang Z. X. , Wang Z. , Li J. X. , Zhou Q. J. , Su Y. J. , Qiao L. J. , Volinsky Alex A. 
Published: May 2017

Hydrogen redistribution under stress-induced hydrogen diffusion and corresponding fracture behaviour of a 960 MPa grade martensitic steel were studied. Slow strain rate tensile (SSRT) tests after hydrogen pre-charging were performed and the fracture surface was observed and analysed. The strain rate ranged from 10−6 to 10−4 s−1. In the pre-charged sample with a certain hydrogen content of 0.62 ppm, hydrogen distribution was homogeneous before the SSRT test. After tensile testing, brittle fracture features appeared in the centre of the fracture surface, while ductile features appeared in the surrounding area. Brittle region size increased with the strain rate slowing down in the range from 10−4 to 5 × 10−6 s−1, while it stabilised at the strain rate slower than 5 × 10−6 s−1. Relationship between the strain rate and the brittle region size was established and discussed based on the present data of hydrogen content in the material. This paper is part of a thematic issue on Hydrogen in Metallic Alloys