bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metamizole (Dipyrone) as an Alternative Agent in Postoperative Analgesia in Patients with Contraindications for Nonsteroidal Anti‐Inflammatory Drugs
Authors: Konijnenbelt‐Peters Jorieke , van der Heijden Charlotte , Ekhart Corine , Bos Jacqueline , Bruhn Jörgen , Kramers Cornelis 
Published: June 2016

AbstractPurposeNonsteroidal anti‐inflammatory drugs (NSAIDs) play an important role in multimodal pain management. In patients with a contraindication for NSAIDs, pain management is challenging. A recent Dutch anesthesiology guideline propagates the use of metamizole (dipyrone) in these patients. Metamizole is a controversial drug, its use being previously discouraged because of the risk for agranulocytosis. We discuss whether metamizole could be an alternative to classical NSAIDs and opioids in postoperative pain management despite this drawback.MethodLiterature review and pharmacovigilance research based on World Health Organization adverse effect registrations.ResultsMetamizole causes fewer gastric and duodenal ulcers than other nonselective NSAIDs, and the risk for bleeding is limited. It is unknown whether it is safer than a nonselective NSAID combined with a proton pump inhibitor. Although the drug appears to be safe for renal function in healthy volunteers, data in high‐risk patients (eg, those with heart or renal failure) are lacking. The incidence of metamizole‐induced agranulocytosis is controversial, but the risk is likely to be limited with short‐term postoperative use in this selected group of patients.ConclusionAlthough firm evidence is lacking, metamizole may be safer for the upper intestinal tract and kidneys than other NSAIDs, and could alternatively be used in patients with an increased risk for stomach or renal problems. Hereby, improved postoperative pain relief can potentially be achieved. The risk for metamizole‐induced agranulocytosis is judged to be acceptable.
Interpretation of Ecological Theory for Physical Activity with the Omaha System
Authors: Olsen Jeanette M. , Baisch Mary J. , Monsen Karen A. 
Published: June 2016

AbstractPhysical inactivity is a global health problem. Public health nurses (PHNs) have great potential to influence population health outcomes in this area. However, methods are needed to increase understanding of the problem and the impact PHNs may have on measuring and changing health behavior. One promising option is PHN documentation of client health data. However, literature examining how health behavior theories align with nursing documentation systems that use standardized terminology is sparse. The purpose of this article was to operationalize an ecological theory with the Omaha System standardized terminology using physical activity as an exemplar. The goal was to provide a method for using PHN clinical documentation to examine physical activity from a theoretical perspective in research and practice. We designed and used a three‐phase process informed by the literature to conceptually map the ecological model for health promotion and the Omaha System. The results of the mapping process reveal the ecological nature of the Omaha System and provide support for measuring and analyzing health‐related behavior problems from an ecological perspective with Omaha System data. This process could be replicated with other health‐related problems and standardized terminologies to guide theoretically based nursing care and research.
Cerebral mechanisms underlying the effects of music during a fatiguing isometric ankle‐dorsiflexion task
Authors: Bigliassi Marcelo , Karageorghis Costas I. , Nowicky Alexander V. , Orgs Guido , Wright Michael J. 
Published: June 2016

AbstractThe brain mechanisms by which music‐related interventions ameliorate fatigue‐related symptoms during the execution of fatiguing motor tasks are hitherto under‐researched. The objective of the present study was to investigate the effects of music on brain electrical activity and psychophysiological measures during the execution of an isometric fatiguing ankle‐dorsiflexion task performed until the point of volitional exhaustion. Nineteen healthy participants performed two fatigue tests at 40% of maximal voluntary contraction while listening to music or in silence. Electrical activity in the brain was assessed by use of a 64‐channel EEG. The results indicated that music downregulated theta waves in the frontal, central, and parietal regions of the brain during exercise. Music also induced a partial attentional switching from associative thoughts to task‐unrelated factors (dissociative thoughts) during exercise, which led to improvements in task performance. Moreover, participants experienced a more positive affective state while performing the isometric task under the influence of music.
Optimal Designs for Longitudinal and Functional Data
Authors: Ji Hao , Müller Hans-Georg 
Published: June 2016

Summary
We propose novel optimal designs for longitudinal data for the common situation where the resources for longitudinal data collection are limited, by determining the optimal locations in time where measurements should be taken. As for all optimal designs, some prior information is needed to implement the optimal designs proposed. We demonstrate that this prior information may come from a pilot longitudinal study that has irregularly measured and noisy measurements, where for each subject one has available a small random number of repeated measurements that are randomly located on the domain. A second possibility of interest is that a pilot study consists of densely measured functional data and one intends to take only a few measurements at strategically placed locations in the domain for the future collection of similar data. We construct optimal designs by targeting two criteria: optimal designs to recover the unknown underlying smooth random trajectory for each subject from a few optimally placed measurements such that squared prediction errors are minimized; optimal designs that minimize prediction errors for functional linear regression with functional or longitudinal predictors and scalar responses, again from a few optimally placed measurements. The optimal designs proposed address the need for sparse data collection when planning longitudinal studies, by taking advantage of the close connections between longitudinal and functional data analysis. We demonstrate in simulations that the designs perform considerably better than randomly chosen design points and include a motivating data example from the Baltimore Longitudinal Study of Aging. The designs are shown to have an asymptotic optimality property.
Optimal Income Taxation and Job Choice
Authors: Boadway Robin , Song Zhen , Tremblay Jean‐François 
Published: June 2016

AbstractIn this paper, we study optimal income taxation when different job types exist for workers of different skills. Each job type has some feasible range of incomes from which workers choose by varying labor supply. Workers are more productive than others in the jobs that suit them best. The model combines features of the classic optimal tax literature with labor variability along the intensive margin, with the extensive‐margin approach where workers make discrete job choices and/or participation decisions. We find that first‐best maximin utility can be achieved in the second‐best, and marginal tax rates below the top can be negative or zero.
Truthtelling in Matching Markets
Authors: Hagenbach Jeanne , Koessler Frédéric , Trégouët Thomas 
Published: June 2016

AbstractWe analyze a search and matching model with non‐transferable utility and asymmetric information. Randomly paired agents go through an evaluation phase, at the end of which they discover each other's types and choose to match or not. Before deciding to enter this phase, agents can communicate through cheap talk. We provide conditions for this communication to be informative, and we examine how it affects agents' welfare. We show that communication is Pareto‐improving only when the matching is assortative in the absence of communication and left unchanged by information transmission.
Optimal Regulation of Multinationals under Collusion
Authors: Karabay Bilgehan 
Published: June 2016

AbstractThis paper analyses the optimal collusion‐proof mechanism for the regulation of multinational firms (MNFs) in foreign direct investment (FDI) projects. There is a host country with a profitable investment opportunity. Either a multinational firm (MNF) or a local firm (LF) can undertake this project; nonetheless due to its firm‐specific advantage, and the MNF has the potential to create a larger surplus. The host government faces an informational constraint such that it cannot observe the extra surplus the MNF can generate. Using this set‐up, Karabay (2010) shows that employing foreign ownership restrictions to force a joint venture (JV) can help the host government to partially overcome its information disadvantage. In this paper, we extend Karabay (2010) by studying the host government's optimal regulatory policy when the MNF and the LF can collude. It turns out collusion imposes no cost on the host government and the expected welfare attained in the absence of collusion can still be secured under collusion.
Treating pressure ulcers with clostridial collagenase ointment: Results from the US Wound Registry
Authors: Carter Marissa J. , Gilligan Adrienne M. , Waycaster Curtis R. , Fife Caroline E. 
Published: June 2016

We assessed the clinical effectiveness of clostridial collagenase ointment (CCO) as an adjunct to selective debridement compared with selective debridement alone for the management of stage IV pressure ulcers (PU) in the hospital outpatient department setting. Outcome data were derived from retrospective de‐identified electronic medical records from 2007 to 2013 using the US Wound Registry. A propensity score method was used to adjust for selection bias and to test for treatment effect between PU treated with CCO plus selective debridement vs. selective debridement alone. A total of 337 CCO and 336 non‐CCO stage IV PU were identified. The proportion of wounds closed at any time (e.g., at 1 or 2 years) was two times greater for stage IV PU treated with CCO compared with those not treated with CCO. Kaplan–Meier analysis showed that time to wound closure at 1 year was significantly faster for PU treated with CCO vs. PU not treated with CCO. Among those with five or more CCO applications or selective debridement treatments, significantly more CCO‐treated PU were closed at 1 or 2 years than non–CCO‐treated PU. CCO as an adjunct to selective debridement improved clinical outcomes and provided faster rates of closure of stage IV PU relative to selective debridement alone.
PREDICTORS AND THEIR DOMAIN FOR STATISTICAL DOWNSCALING OF CLIMATE IN BANGLADESH
Authors: Alamgir Mahiuddin , Hadi Pour Sahar , Mohsenipour Morteza , Mehedi Hasan M. , Ismail Tarmizi 
Published: June 2016

Reliable projection of future rainfall in Bangladesh is very important for the assessment of possible impacts of climate change and implementation of necessary adaptation and mitigation measures. Statistical downscaling methods are widely used for downscaling coarse resolution general circulation model (GCM) output at local scale. Selection of predictors and their spatial domain is very important to facilitate downscaling future climate projected by GCMs. The present paper reports the finding of the study conducted to identify the GCM predictors and demarcate their climatic domain for statistical downscaling in Bangladesh at local or regional scale. Twenty-six large scale atmospheric variables which are widely simulated GCM predictors from 45 grid points around the country were analysed using various statistical methods for this purpose. The study reveals that large-scale atmospheric variables at the grid points located in the central-west part of Bangladesh have the highest influence on rainfall. It is expected that the finding of the study will help different meteorological and agricultural organizations of Bangladesh to project rainfall and temperature at local scale in order to provide various agricultural or hydrological services.
Sources of protons and a role for bicarbonate in inhibitory feedback from horizontal cells to cones in Ambystoma tigrinum retina
Authors: Warren Ted J. , Van Hook Matthew J. , Supuran Claudiu T. , Thoreson Wallace B. 
Published: June 2016

Key points
In the vertebrate retina, photoreceptors influence the signalling of neighbouring photoreceptors through lateral‐inhibitory interactions mediated by horizontal cells (HCs). These interactions create antagonistic centre‐surround receptive fields important for detecting edges and generating chromatically opponent responses in colour vision.
The mechanisms responsible for inhibitory feedback from HCs involve changes in synaptic cleft pH that modulate photoreceptor calcium currents. However, the sources of synaptic protons involved in feedback and the mechanisms for their removal from the cleft when HCs hyperpolarize to light remain unknown.
Our results indicate that Na+–H+ exchangers are the principal source of synaptic cleft protons involved in HC feedback but that synaptic cleft alkalization during light‐evoked hyperpolarization of HCs also involves changes in bicarbonate transport across the HC membrane.
In addition to delineating processes that establish lateral inhibition in the retina, these results contribute to other evidence showing the key role for pH in regulating synaptic signalling throughout the nervous system.
AbstractLateral‐inhibitory feedback from horizontal cells (HCs) to photoreceptors involves changes in synaptic cleft pH accompanying light‐evoked changes in HC membrane potential. We analysed HC to cone feedback by studying surround‐evoked light responses of cones and by obtaining paired whole cell recordings from cones and HCs in salamander retina. We tested three potential sources for synaptic cleft protons: (1) generation by extracellular carbonic anhydrase (CA), (2) release from acidic synaptic vesicles and (3) Na+/H+ exchangers (NHEs). Neither antagonizing extracellular CA nor blocking loading of protons into synaptic vesicles eliminated feedback. However, feedback was eliminated when extracellular Na+ was replaced with choline and significantly reduced by an NHE inhibitor, cariporide. Depriving NHEs of intracellular protons by buffering HC cytosol with a pH 9.2 pipette solution eliminated feedback, whereas alkalinizing the cone cytosol did not, suggesting that HCs are a major source for protons in feedback. We also examined mechanisms for changing synaptic cleft pH in response to changes in HC membrane potential. Increasing the trans‐membrane proton gradient by lowering the extracellular pH from 7.8 to 7.4 to 7.1 strengthened feedback. While maintaining constant extracellular pH with 1 mm HEPES, removal of bicarbonate abolished feedback. Elevating intracellular bicarbonate levels within HCs prevented this loss of feedback. A bicarbonate transport inhibitor, 4,4′‐diisothiocyano‐2,2′‐stilbenedisulfonic acid (DIDS), also blocked feedback. Together, these results suggest that NHEs are the primary source of extracellular protons in HC feedback but that changes in cleft pH accompanying changes in HC membrane voltage also require bicarbonate flux across the HC membrane.
Validity, Reliability, and Sensitivity of a Volleyball Intermittent Endurance Test
Authors: Rodríguez-Marroyo Jose A. , Medina-Carrillo Javier , García-López Juan , Morante Juan C. , Villa José G. , Foster Carl 
Published: June 2016

Purpose:To analyze the concurrent and construct validity of a volleyball intermittent endurance test (VIET). The VIET’s test–retest reliability and sensitivity to assess seasonal changes was also studied.Methods:During the preseason, 71 volleyball players of different competitive levels took part in this study. All performed the VIET and a graded treadmill test with gas-exchange measurement (GXT). Thirty-one of the players performed an additional VIET to analyze the test–retest reliability. To test the VIET’s sensitivity, 28 players repeated the VIET and GXT at the end of their season.Results:Significant (P < .001) relationships between VIET distance and maximal oxygen uptake (r = .74) and GXT maximal speed (r = .78) were observed. There were no significant differences between the VIET performance test and retest (1542.1 ± 338.1 vs 1567.1 ± 358.2 m). Significant (P < .001) relationships and intraclass correlation coefficient (ICC) were found (r = .95, ICC = .96) for VIET performance. VIET performance increased significantly (P < .001) with player performance level and was sensitive to fitness changes across the season (1458.8 ± 343.5 vs 1581.1 ± 334.0 m, P < .01).Conclusions:The VIET may be considered a valid, reliable, and sensitive test to assess the aerobic endurance in volleyball players.
Influence of Isoinertial-Pneumatic Mixed Resistances on Force–Velocity Relationship
Authors: Avrillon Simon , Jidovtseff Boris , Hug François , Guilhem Gaël 
Published: June 2016

Purpose:Muscle strengthening is commonly based on the use of isoinertial loading, whereas variable resistances such as pneumatic loading may be implemented to optimize training stimulus. The purpose of the current study was to determine the effect of the ratio between pneumatic and isoinertial resistance on the force–velocity relationship during ballistic movements.Methods:A total of 15 participants performed 2 concentric repetitions of ballistic bench-press movements with intention to throw the bar at 30%, 45%, 60%, 75%, and 90% of the maximal concentric repetition with 5 resistance ratios including 100%, 75%, 50%, 25%, or 0% of pneumatic resistance, the additional load being isoinertial. Force-, velocity-, and power-time patterns were assessed and averaged over the concentric phase to determine the force–velocity and power–velocity relationships for each resistance ratio.Results:Each 25% increase in the pneumatic part in the resistance ratio elicited higher movement velocity (+0.11 ± 0.03 m/s from 0% to 80% of the concentric phase) associated with lower force levels (–43.6 ± 15.2 N). Increased isoinertial part in the resistance ratio resulted in higher velocity toward the end of the movement (+0.23 ± 0.01 m/s from 90% to 100%).Conclusions:The findings show that the resistance ratio could be modulated to develop the acceleration phase and force toward the end of the concentric phase (pneumatic-oriented resistance). Inversely, isoinertial-oriented resistance should be used to develop maximal force and maximal power. Resistance modality could, therefore, be considered an innovative variable to modulate the training stimulus according to athletic purposes.
Temperature-dependent photoluminescence spectra of ZnO nanorod arrays grown on transparent conducting substrates by hydrothermal routes
Authors: Li S. P. , Gu X. Q. 
Published: June 2016

Ordered ZnO nanorod (NR) arrays have been prepared on transparent conducting oxide (TCO) substrates by a facile seed-assisted hydrothermal route. The optical properties of the samples were investigated by temperature-dependent photoluminescence (PL) spectra. Two sharp peaks were clearly identified in the ultraviolet (UV) band, located at 3.34 and 3.26 eV in 10 K spectrum, and were labeled as peaks A and B. Both the peaks exhibited different quenching behaviors, although their red-shift characteristics were almost the same with temperature rising. Something gave rise to a possible mechanism to explain such a behavior. Specifically, peaks A and B were assigned to the bound excitons and carrier transitions from shallow donor levels to the valence band, respectively. The detailed analysis will be illustrated in this study. It is hoped that this work could render guided information for understanding the carrier recombination and dynamics behavior in single-crystal ZnO nanostructures.
Effects of reduction temperature on copper nanowires growth by thermal reduction of copper oxide nanowires
Authors: Rashid Norhana Mohamed , Kishi Naoki , Soga Tetsuo 
Published: June 2016

Metallic Cu nanowires have been synthesized by thermal reduction of CuO nanowires in low concentration hydrogen environment. The Cu nanowires can be formed after removing oxide group from the metal oxide nanowires within temperature range from 200[Formula: see text]C to 500[Formula: see text]C. These nanowires have twisted structure with 100–200 nm and average lengths of 10 [Formula: see text]m can be obtained in optimum temperature range 300–400[Formula: see text]C reduced for 30 min. The X-ray diffraction (XRD) pattern shows Cu peaks recognized at (111), (200) and (220). Scanning electron microscopy (SEM) images reveal the reduction temperatures strongly affect the nanowires formation. Transmission electron microscopy (TEM) images confirmed that Cu nanowires have single crystalline structures with 0.21 nm fringe spacing which correspond to (111) growth direction. The results indicate that thermal reduction of copper oxide nanowires in low concentration hydrogen environment can produce high purity and single crystalline Cu nanowires.
The 3rd Workshop on Social and Algorithmic Issues in Business Support
Authors: Wojciechowski Adam , Mishra Alok 
Published: June 2016

This is a report from the 3rd International Workshop on "Social and Algorithmic Issues in Business Support" (SAIBS), which was organized in conjunction with the 7th Language and Technology Conference in Poznan, Poland, on November 28, 2015. The main issue focused in research papers presented during the workshop was deriving knowledge from various text artifacts and converting the data into algorithms to use it in a systematic way in parallel cases.
Utilizing social wisdom begins with observation of human behavior, analysis of artifacts, building paradigms on statistical models and converting them into algorithms. Social trend observed in XXI century, networking and business activity has several sources. A base for rapid growth is accessible technology. But the force that drives people to active contribution is an everyday challenge to become recognizable and rich. Crowd creativity is a process of merging efforts and distributed resources in order to produce new quality and new products. Utilizing social energy and productivity provides beginning to new business paradigms, which converted into algorithms, may be applied in various domains. The 3rd SAIBS Workshop was a place to discuss methods of knowledge discovery in text resources and other artifacts as well as analysis of human behavior materialized and documented in databases and artifacts. An accent was focused on utilization and commercial benefit coming from analysis and converting knowledge into algorithms.