bluuebunny/crossref_metadata_2025_split huggingface dataset:
Light‐Induced Tuning and Reconfiguration of Nanophotonic Structures
Authors: Makarov Sergey V. , Zalogina Anastasia S. , Tajik Mohammad , Zuev Dmitry A. , Rybin Mikhail V. , Kuchmizhak Aleksandr A. , Juodkazis Saulius , Kivshar Yuri 
Published: August 2017

AbstractInteraction of light pulses of various durations and intensities with nanoscale photonic structures plays an important role in many applications of nanophotonics for high‐density data storage, ultra‐fast data processing, surface coloring and sensing. A design of optically tunable and reconfigurable structures made from different materials is based on many important physical effects and advances in material science, and it employs the resonant character of light interaction with nanostructures and strong field confinement at the nanoscale. Here we review the recent progress in physics of tunable and reconfigurable nanophotonic structures of different types. We start from low laser intensities that produce weak reversible changes in nanostructures, and then move to the discussion of non‐reversible changes in photonic structures. We focus on three platforms based on metallic, dielectric and hybrid resonant photonic structures such as nanoantennas, nanoparticle oligomers and nanostructured metasurfaces. Main challenges and key advantages of each of the approaches focusing on applications in advanced photonic technologies are also discussed.
Safety of non‐ablative fractional laser for acne scars within 1 month after treatment with oral isotretinoin: A randomized split‐face controlled trial
Authors: Saluja Sandeep S. , Walker Matthew L. , Summers Erika M. , Tristani‐Firouzi Payam , Smart David R. 
Published: August 2017

Background and ObjectiveBased on reports of poor wound healing and scarring, it is currently recommended that patients wait 6 months after completion of oral isotretinoin therapy before the safe initiation of laser treatment. Our aim was to evaluate the safety of non‐ablative fractional laser (NAFL) treatment for acne scars within 1 month after isotretinoin therapy.Study Design/MethodsThis was a randomized split‐face controlled trial involving 10 patients with acne scars who had completed isotretinoin treatment. All patients received three treatments each spaced 4 weeks apart with an erbium‐doped 1550 nm NAFL on one side of the face within 1 month after isotretinoin therapy. The untreated side acted as a control. Wound healing and adverse effects as well as acne scar improvement were evaluated by two blinded dermatologists.ResultsAll patients demonstrated normal wound healing post NAFL treatments, and neither hypertrophic scars nor keloids were observed. Acne scar improvement was satisfactory.ConclusionNAFL treatment for acne scarring appears to be well tolerated within 1 month of completing isotretinoin treatment. Dermatologists should reevaluate the current recommendation to wait 6 months after isotretinoin treatment for acne scar revision with lasers. Other larger studies are necessary to further challenge this dogma. Lasers Surg. Med. 49:886–890, 2017. © 2017 Wiley Periodicals, Inc.
Hydrocarbon‐Soluble Piperazine‐Containing Dilithium Anionic Initiator for High Cis‐1,4 Isoprene Polymerization
Authors: Schultz Alison R. , Bobade Sachin , Scott Philip J. , Long Timothy E. 
Published: August 2017

AbstractThe synthesis of 1,4‐bis[4‐(1‐phenylethenyl)benzyl] piperazine and subsequent reaction with sec‐butyllithium enables a novel piperazine‐containing difunctional organolithium initiator for the living anionic polymerization of isoprene. Piperazine provides a polar unit within the difunctional initiator, promoting ion dissociation and miscibility with hydrocarbon solvents, and enabling the formation of well‐defined polyisoprene homopolymers with predictable molecular weights and controlled microstructure. In situ Fourier transform infrared spectroscopy monitors the dilithium initiator formation and the anionic polymerization of isoprene, revealing kinetic insight into this synthetic method. Furthermore, sequential monomer addition with styrene affords poly(styrene‐block‐isoprene‐block‐styrene) triblock copolymers with controlled molecular weights and narrow polydispersities. This novel initiator facilitates the synthesis of thermoplastic elastomers with desired cis‐1,4 microstructure in polydienes.
The nasal and gut microbiome in Parkinson's disease and idiopathic rapid eye movement sleep behavior disorder
Authors: Heintz‐Buschart Anna , Pandey Urvashi , Wicke Tamara , Sixel‐Döring Friederike , Janzen Annette , Sittig‐Wiegand Elisabeth , Trenkwalder Claudia , Oertel Wolfgang H. , Mollenhauer Brit , Wilmes Paul 
Published: August 2017

ABSTRACTBackgroundIncreasing evidence connects the gut microbiota and the onset and/or phenotype of Parkinson's disease (PD). Differences in the abundances of specific bacterial taxa have been reported in PD patients. It is, however, unknown whether these differences can be observed in individuals at high risk, for example, with idiopathic rapid eye movement sleep behavior disorder, a prodromal condition of α‐synuclein aggregation disorders including PD.ObjectivesTo compare microbiota in carefully preserved nasal wash and stool samples of subjects with idiopathic rapid eye movement sleep behavior disorder, manifest PD, and healthy individuals.MethodsMicrobiota of flash‐frozen stool and nasal wash samples from 76 PD patients, 21 idiopathic rapid eye movement sleep behavior disorder patients, and 78 healthy controls were assessed by 16S and 18S ribosomal RNA amplicon sequencing. Seventy variables, related to demographics, clinical parameters including nonmotor symptoms, and sample processing, were analyzed in relation to microbiome variability and controlled differential analyses were performed.ResultsDifferentially abundant gut microbes, such as Akkermansia, were observed in PD, but no strong differences in nasal microbiota. Eighty percent of the differential gut microbes in PD versus healthy controls showed similar trends in idiopathic rapid eye movement sleep behavior disorder, for example, Anaerotruncus and several Bacteroides spp., and correlated with nonmotor symptoms. Metagenomic sequencing of select samples enabled the reconstruction of genomes of so far uncharacterized differentially abundant organisms.ConclusionOur study reveals differential abundances of gut microbial taxa in PD and its prodrome idiopathic rapid eye movement sleep behavior disorder in comparison to the healthy controls, and highlights the potential of metagenomics to identify and characterize microbial taxa, which are enriched or depleted in PD and/or idiopathic rapid eye movement sleep behavior disorder. © 2017 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease
Authors: Trezzi Jean‐Pierre , Galozzi Sara , Jaeger Christian , Barkovits Katalin , Brockmann Kathrin , Maetzler Walter , Berg Daniela , Marcus Katrin , Betsou Fay , Hiller Karsten , Mollenhauer Brit 
Published: August 2017

AbstractObjective:The purpose of this study was to profile cerebrospinal fluid (CSF) from early‐stage PD patients for disease‐related metabolic changes and to determine a robust biomarker signature for early‐stage PD diagnosis.Methods:By applying a non‐targeted and mass spectrometry‐driven approach, we investigated the CSF metabolome of 44 early‐stage sporadic PD patients yet without treatment (DeNoPa cohort). We compared all detected metabolite levels with those measured in CSF of 43 age‐ and gender‐matched healthy controls. After this analysis, we validated the results in an independent PD study cohort (Tübingen cohort).Results:We identified that dehydroascorbic acid levels were significantly lower and fructose, mannose, and threonic acid levels were significantly higher (P < .05) in PD patients when compared with healthy controls. These changes reflect pathological oxidative stress responses, as well as protein glycation/glycosylation reactions in PD. Using a machine learning approach based on logistic regression, we successfully predicted the origin (PD patients vs healthy controls) in a second (n = 18) as well as in a third and completely independent validation set (n = 36). The biomarker signature is composed of the three markers—mannose, threonic acid, and fructose—and allows for sample classification with a sensitivity of 0.790 and a specificity of 0.800.Conclusion:We identified PD‐specific metabolic changes in CSF that were associated with antioxidative stress response, glycation, and inflammation. Our results disentangle the complexity of the CSF metabolome to unravel metabolome changes related to early‐stage PD. The detected biomarkers help understanding PD pathogenesis and can be applied as biomarkers to increase clinical diagnosis accuracy and patient care in early‐stage PD. © 2017 International Parkinson and Movement Disorder Society
Effects of monthly feedback of VFA measured by dual BIA method in Japanese patients with obesity: a randomized controlled study
Authors: Moriyasu T. , Hosoda K. , Tanaka‐Mizuno S. , Konda M. , Ueshima K. , Ida M. , Nin K. 
Published: August 2017

SummaryObjectiveTo investigate the effects of monthly feedback of changes in visceral fat area (VFA) as measured by dual bioelectrical impedance analysis method and the importance of VFA in individuals with obesity.MethodsThirty‐eight Japanese patients with obesity underwent VFA measurements. The feedback group was given feedback on VFA measurements each month for 4 months. The control group underwent VFA measurements at the beginning and end of the study but was not informed of the results. All the study participants completed eating behaviour and weight efficacy lifestyle questionnaires.ResultsMean age was 53.9 (14.3) years; mean body mass index was 30.6 (4.3) kg m−2. At the 4‐month follow‐up, there was no significant difference in VFA reduction between the control and feedback groups (−4.4% vs. −3.0%; 95% CI, −3.8 to 5.5). In post‐hoc analysis using the overall group irrespective of allocation, changes of eating style were significantly associated with a reduction in VFA at 4 months (p = 0.034).ConclusionsMonthly feedback on changes in VFA does not reduce VFA. More frequent feedback may be required. In post‐hoc analysis, changes of eating style were associated with a reduction in VFA.
Validated Method for Strigolactone Quantification by Ultra High‐Performance Liquid Chromatography – Electrospray Ionisation Tandem Mass Spectrometry Using Novel Deuterium Labelled Standards
Authors: Boutet‐Mercey Stéphanie , Perreau François , Roux Amélie , Clavé Guillaume , Pillot Jean‐Paul , Schmitz‐Afonso Isabelle , Touboul David , Mouille Grégory , Rameau Catherine , Boyer François‐Didier 
Published: August 2017

AbstractIntroductionStrigolactones (SLs) are important plant hormones. They are difficult to analyse because they occur in very small concentrations especially in comparison with other plant hormones and other substances can interfere with their detection.ObjectiveTo develop a procedure for the extraction, purification and quantification of SLs from plant roots.MethodologySamples were prepared by extraction of plant root tissues with ethyl acetate. Then the extracts were further purified with silica column chromatography. The natural SLs in the final extracts were quantified using novel deuterium labelled SLs. The results of the methodology were compared with those of the procedure of Yoneyama and coworkers.ResultsThis procedure required about 1‐g root samples to detect and quantify simultaneously the SLs (orobanchyl acetate and fabacyl acetate) concentration with high reliability.ConclusionA method was developed for determining endogenous fabacyl acetate and orobanchyl acetate in plant tissue based on novel deuterium labelled standards. A method of orobanchol quantification using a synthetic SL GR24 as internal standard was proposed. Copyright © 2017 John Wiley & Sons, Ltd.
Visible to NIR absorbing C–N and C–C bonding squaraines: A computational study
Authors: Tripathi Anuj , Dhanda Promila , Prabhakar Chetti 
Published: August 2017

AbstractWe report a comparative computational study of 2 series of molecules with C–N bonding squaraines (NSQ) and C–C bonding squaraines (CSQ), having absorption from visible to near infrared region (350‐800 nm). The NSQ are considered as molecules with break‐in conjugation, and CSQ are considered as molecules with complete conjugation in molecular backbone. The lowest electronic excitations in CSQ molecules are always having around 200 nm red shifted absorption than its corresponding NSQ molecules. The reason for this drastic red shift in CSQ series than NSQ has been systematically studied by density functional theory, time‐dependent density functional theory, and symmetry adopted cluster configuration interaction methods. The CSQ series are showing less charge transfer than NSQ, but having small diradical character. This study may be helpful in design and synthesis of new squaraine dyes, which are useful in materials applications.
Estradiol promotes epithelial‐to‐mesenchymal transition in human benign prostatic epithelial cells
Authors: Shi Xiaoyu , Peng Yanfei , Du Xiaoling , Liu Haitao , Klocker Helmut , Lin Qimei , Shi Jiandang , Zhang Ju 
Published: August 2017

BackgroundEpithelial‐to‐mesenchymal transition (EMT) is involved in pathogenesis of human benign prostatic hyperplasia (BPH). Estrogenic signaling pathways may stimulate the induction of EMT. However, the details of estradiol (E2) and estrogen receptors (ERs) effects on EMT, as well as E2‐induced modulation of benign prostatic epithelial cell phenotype in vitro have not been completely clarified.MethodsThe effects of E2 on EMT markers and cytokeratins (CKs) expression were evaluated in benign epithelial cell lines BPH‐1 and RWPE‐1, which were cultured both in two‐dimensional (2D) culture and three‐dimensional (3D) culture model using hanging drop technique or 3D Matrigel model. ER antagonist, ICI182,780, was used to confirm the regulatory effects of E2 on EMT and phenotypic modulation. In 3D culture, immunohistochemical stainings were performed to detect the specific phenotype of cells that underwent EMT in acinar‐like spheroids formed by RWPE‐1. To illustrate the exact function of ERs in E2‐induced EMT and phenotypic modulation, specific short interfering RNAs (siRNAs), and agonists were used to knockdown or activate individual ERs, respectively.ResultsE2‐induced EMT was observed both in 2D and 3D culture, with related regulation of EMT markers expression at both mRNA and protein level. In addition, E2 down‐regulated luminal cell type markers CK18 and CK8 and up‐regulated basal cell type markers CK5 and CK14. E2 also increased intermediate type markers CK15 and CK17, while it attenuated CK19 in 3D culture. ICI182,780 blocked E2‐induced EMT and cell phenotypic switching. In 3D Matrigel culture, Vimentin was co‐expressed with ERα and CK17, as well as with SMemb, which is related to cell status switching and proliferation. Knockdown of ERα but not GPR30 inhibited EMT, while ERβ knockdown facilitated EMT process. Knockdown of ERα blocked E2‐induced EMT both in RWPE‐1 and BPH‐1. MRNA expression of EMT markers was stimulated by ERα‐specific agonist PPT and inhibited by ERβ‐specific agonist DPN.ConclusionsEstrogenic effect mediated by ERα can promote EMT. E2 is also an inductive factor of cell phenotypic switching. Cell type modulation is associated with E2‐induced EMT in benign prostatic epithelial cells. Taken together the results support a contribution of estrogens to the pathogenesis of BPH in elderly men.
The impact of restrictions on neonicotinoid and fipronil insecticides on pest management in maize, oilseed rape and sunflower in eight European Union regions
Authors: Kathage Jonas , Castañera Pedro , Alonso‐Prados José Luis , Gómez‐Barbero Manuel , Rodríguez‐Cerezo Emilio 
Published: August 2017

AbstractBACKGROUNDIn 2013, the European Commission restricted the use of three neonicotinoids (clothianidin, imidacloprid and thiamethoxam) and the pyrazole fipronil, which are widely used to control early‐season pests. Here, we used original farm survey data to examine the impact of the restrictions on pest management practices in eight regional case studies including maize, oilseed rape and sunflower in seven European Union (EU) countries.RESULTSIn four case studies, farmers switched to using untreated seeds as no alternative seed treatments were available. In three case studies, farmers switched to using unrestricted neonicotinoid‐ or pyrethroid‐treated seeds. In five case studies, farmers increased the use of soil or foliar treatments, with pyrethroids as the principal insecticide class. Other changes in pest management practices ranged from increased sowing density to more frequent scouting for pests. Many farmers perceived that the time, cost and amount of insecticides required to protect crops increased, along with pest pressure. Alternative seed treatments were mostly perceived as being less effective than the restricted seed treatments.CONCLUSIONFarmers generally relied on alternative seed treatments or more soil/foliar treatments in the first growing season after the restrictions took effect. Further study is required to assess the effectiveness and sustainability of these alternatives compared with the restricted insecticides. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Spectral separability and mapping potential of cassava leaf damage symptoms caused by whiteflies (Bemisia tabaci)
Authors: Sims Neil C , De Barro Paul , Newnham Glenn J , Kalyebi Andrew , Macfadyen Sarina , Malthus Tim J 
Published: August 2017

AbstractBACKGROUNDThis study examines whether leaf spectra can be used to measure damage to cassava plants from whitefly (Bemisia tabaci), and the potential to translate measurements from leaf to landscape scale in eastern Africa. Symptoms of the cassava brown streak disease (CBSD) and cassava mosaic disease (CMD) viruses, and sooty mould (SM) blackening of lower leaves from whiteflies feeding on the upper leaves, were measured at the leaf scale with a high‐resolution spectroradiometer and a single photon avalanche diode (SPAD) meter, which retrieves relative chlorophyll concentration. Spectral measurements were compared to the five‐level visual scores used to assess the severity of each of the three damaging agents in the field, and also to leaf chemistry data.RESULTSLeaves exhibiting severe CBSD and CMD were spectrally indistinguishable from leaves without any symptoms. Severe SM was spectrally distinctive but is likely to be difficult to map because of its occurrence in the lower crown. SPAD measurements were highly correlated with most foliar chemistry measurements and field scores of disease severity. Regression models between simulated Sentinel 2 bands, field scores and SPAD measurements were strongest using wavelengths with high importance weightings in random forest models.CONCLUSIONSPAD measurements are highly correlated to many foliar chemistry parameters, and should be considered for use in mapping disease severity over larger areas. Remaining challenges for mapping relate to the subtle expression of symptoms, the spatial distribution of disease severity within fields, and the small size and complex structure of the cassava fields themselves. © 2017 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Factors affecting trap catch in pheromone‐based monitoring of saddle gall midge Haplodiplosis marginata (Diptera: Cecidomyiidae)
Authors: Rowley Charlotte , Cherrill Andrew J , Leather Simon R , Hall David R , Pope Tom W 
Published: August 2017

AbstractBACKGROUNDThe saddle gall midge, Haplodiplosis marginata (von Roser) (Diptera: Cecidomyiidae), is a pest of cereal crops in Europe. Outbreaks are difficult to predict and effective monitoring tools are required to ensure the effectiveness of pest management options. The female sex pheromone (R)‐2‐nonyl butyrate provides the basis of a highly effective lure for this insect. Here, we demonstrate how the success of this lure can be influenced by parameters such as trap location, lure age, and interference between traps fitted with these lures.RESULTSA pheromone lure containing (R)‐2‐nonyl butyrate attracted male midges for at least 9 weeks under field conditions. Pheromone‐baited traps performed best when situated away from field margins and below the height of the crop. Interference between nearby traps was evident at distances <20 m.CONCLUSIONThe results presented here offer new insights into the behavioural responses of male H. marginata to the female sex pheromone and provide practical recommendations for the use of H. marginata pheromone traps in the field. © 2017 Society of Chemical Industry
Uncertainty quantification in theoretical spectroscopy: The structural sensitivity of X‐ray emission spectra
Authors: Oung Sangwar Wadtey , Rudolph Julian , Jacob Christoph R. 
Published: August 2017

AbstractWe present a methodology for analyzing the dependence of molecular spectra calculated with quantum‐chemical methods on the underlying molecular structure. This analysis is applied to investigate the structural sensitivity of calculated valence‐to‐core X‐ray emission (VtC‐XES) spectra for the test case of three iron carbonyl complexes, Fe(CO)5, [FeCp(CO)2(THF)]+ (Cp = cyclopentadienyl, THF = tetrahydrofuran), and Fe(CO)3(cod) (cod = cyclooctadienyl). Based on this analysis, we discuss how the VtC‐XES spectra depend on changes of metal–ligand bond distances and bond angles as well as on the structure of the ligands. The benefits of such an analysis of the structural sensitivity are discussed. Our methodology can serve as a first step toward quantifying and accounting for uncertainties due to the underlying model structure in theoretical spectroscopy.
Effect of hydrogen‐bonded interactions on the energetics and spectral properties of the astromolecule aminoacetonitrile
Authors: Chakraborty Sumana , Lima Bonifácio Coelho de , Silva Arnaldo Machado da , Chaudhuri Puspitapallab 
Published: August 2017

AbstractA detailed and systematic electronic structure calculation has been performed to analyze the hydrogen‐bonded interaction of aminoacetonitrile (H2NCH2CN) with hydrogen cyanide (HCN) and Glycine (H2NCH2COOH). Both HCN and aminoacetonitrile have already been detected in the interstellar medium (ISM) and their active role in the molecular mechanisms of glycine production has already been recognized. Four different density functional models have been used to study the effect of hydrogen bond formation on the energetic stability and vibrational spectra of the aminoacetonitrile‐HCN and aminoacetonitrile‐glycine complexes in gas phase. The aminoacetonitrile‐glycine dimer is energetically far more stable than all forms of aminoacetonitrile‐HCN dimers. Elastic and inelastic scattering of light off the hydrogen‐bonded clusters have been investigated in details via Rayleigh and Raman spectroscopic parameters. The dipole moments and depolarization ratios are found to be sensitive on the type of hydrogen‐bond network. The mean polarizabilty show appreciable dependence on the choice of the DFT‐model. In general, all the chemical groups (OH, CN, NH2, and CH) that participate directly in the hydrogen bond formation suffer appreciable variation in the intensity of vibration.