bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mucosite Oral induzida por terapia oncológica – Uma revisão de literatura.
Authors: Cicchelli Monise Queiroz , Guerreiro Leila , Costa Agda Santana , Marques Raquel De Santana Oliveira , Carrera Manoela , Martins Gabriela Botelho , Lima Hayana Ramos , Medrado Alena Peixoto 
Published: July 2017

<p class="MsoNormal" style="margin-bottom: .0001pt; text-align: justify; line-height: 150%; mso-layout-grid-align: none; text-autospace: none;"><span style="font-size: 12.0pt; line-height: 150%; font-family: ";Times New Roman";,";serif";;">O câncer é considerado uma doença genética, na qual os genes que sofreram mutações por motivos físicos ou químicos, modificam a função biológica natural. Os métodos mais eficazes para a destruição de células tumorais ainda são a quimioterapia e a radioterapia, porém, seus efeitos colaterais, na maioria das vezes, interferem na qualidade de vida dos pacientes. Dentre as diversas complicações envolvidas no tratamento antineoplásico, destaca-se a mucosite oral. A presente revisão de literatura objetiva descrever a etiopatogênese da MO e destaca as principais complicações provenientes deste tipo de lesão. Por se tratar de um processo inflamatório que acomete a mucosa oral e estar associada a quadros de desconforto e dor, é importante tentar proporcionar ao paciente afetado por esta condição clínica alívio da sintomatologia dolorosa. Há na literatura o registro do emprego de algumas medidas profiláticas e terapêuticas para a mucosite provocada por oncoterapia, tais como uso de agentes físicos e químicos. O laser, por exemplo, é uma forma de radiação não ionizante e com alta concentração, não invasiva e bem tolerada pelo organismo. É de grande importância a realização de estudos sobre o tema para que se tenha dados e parâmetros de análise suficientes para melhorar a qualidade de vida dos pacientes em tratamento contra o câncer.</span></p>
Atenção farmacêutica humanizada em pacientes hipertensos no Hospital Universitário Lauro Wanderley (HULW)
Authors: SOUSA ANA LETÍCIA BRAZ , FERREIRA EWERTON DA COSTA , GUEDES DIEGO NUNES , COSTA KARLA VERUSKA MARQUES CAVALCANTE , CORREIA NADJA AZEVEDO , ALBUQUERQUE KATY LISIAS GONDIM DIAS 
Published: July 2017

<p>Pharmaceutical Care is a practice that the main purpose is to improve the patient’s quality of life who use frequently drugs, especially whose chronic use. Hypertension is considered a public health problem, with significant risk factors to increase cardiovascular issues in a population. Patients with this type of chronic disease can use a specific medication to stabilize their clinical system. In addition, these patients often use the medication improperly as a different drug amount or quality and stored incorrectly in their home. Through this pharmaceutical care practice, the pharmacist may interact directly with the patient to identify their needs related with drugs. Given these considerations, this study aim to develop a safer and more effective antihypertensive pharmacotherapy providing information about the correct and safe drugs use. This is the way to avoid the patients with early return in a hospital for treatments.</p>
Osteoartrite: prevalência e presença de fatores de risco em idosos ativos
Authors: Pancotte Julia , Bortoluzzi Emanuelly Casal , Graeff Daniela Bertol , Sant'Anna Alves Ana Luísa , Wibelinger Lia Mara , Doring Marlene 
Published: July 2017

<p>O objetivo deste estudo foi investigar a prevalência de osteoartrite e a presença de fatores de risco em frequentadores de um centro de convivência. Trata-se de um estudo transversal aninhado a um estudo de coorte realizado com 391 adultos e idosos em um centro de convivência e atenção para idosos, de julho/2014 a julho/2015. Foram consideradas as variáveis: presença de osteoartrite, sexo, idade, cor/raça, estado nutricional, quedas, autopercepção de saúde, início da menopausa e auto relato de doenças. Realizou-se análise descritiva e inferencial.<strong> </strong>Dos 391 participantes, 32 (7,7%) possuíam osteoartrite, 377 (96,4%) eram do sexo feminino, 187 (47,9%) com idade entre 60 e 69 anos, 326 (84,1%) cor branca, 191 (56,5%) baixo peso/eutrófico, 63 (16,1%) relataram quedas no último ano, 282 (72,2%) saúde muito boa/boa, 223 (53,9%) hipertensão e 306 (78,3%) das mulheres atingiram a menopausa após os 55 anos. A presença de osteoartrite mostrou-se associada a pior percepção de saúde (p=0,033) e ao relato de quedas (p=0,020). Portanto, a osteoartrite mostrou-se pouco prevalente, possivelmente pela condição fisicamente ativa da amostra, sugerindo a influência da condição física na manifestação dessa doença.</p><p> </p>
Stratosphere and lower mesosphere wind observation and gravity wave activities of the wind field in China using a mobile Rayleigh Doppler lidar
Authors: Zhao Ruocan , Dou Xiankang , Xue Xianghui , Sun Dongsong , Han Yuli , Chen Chong , Zheng Jun , Li Zimu , Zhou Anran , Han Yan , Wang Guocheng , Chen Tingdi 
Published: July 2017

AbstractSince the mobile Rayleigh Doppler lidar of the University of Science and Technology of China was developed in 2013, more than 100 days of valid nighttime wind data from 15 to 60 km altitude were obtained during recent 3 years. The observation locations cover the northwest (midlatitude) of China: Delingha (37.371°N, 97.374°E), Xinzhou (38.425°N, 112.729°E), and Jiuquan (39.741°N, 98.495°E). Recently, we have extracted perturbations of the wind profiles from the wind field measurements and we have found that inertia gravity waves and mountain waves existed at the same time. The results of wind field and several gravity waves cases are shown in this paper. Typical characteristics of the gravity waves are analyzed in this midlatitude area of China. A 2‐D fast Fourier transform of the wind perturbation shows that a dominant stationary wave mode and a downward wave mode exist simultaneously in the spectrum. A band‐pass 2‐D filter was applied to the spectrum followed by inverse fast Fourier transform to separate inertia gravity waves from stationary mountain waves. The horizontal wavelength is retrieved using hodograph methods, indicating that the inertia waves are generated thousands of kilometers away. Observed mountain waves from a combination of vertical wind and leaned line of sight wind measurements show a small‐angle leaned wave front from the horizontal direction. This kind of gravity wave observation of the stratospheric wind field and its wave patterns is rare and significant for the study of atmospheric dynamics.
Trophic pathways of phytoplankton size classes through the zooplankton food web over the spring transition period in the north‐west Mediterranean Sea
Authors: Hunt Brian P. V. , Carlotti François , Donoso Katty , Pagano Marc , D'Ortenzio Fabrizio , Taillandier Vincent , Conan Pascal 
Published: July 2017

AbstractKnowledge of the relative contributions of phytoplankton size classes to zooplankton biomass is necessary to understand food‐web functioning and response to climate change. During the Deep Water formation Experiment (DEWEX), conducted in the north‐west Mediterranean Sea in winter (February) and spring (April) of 2013, we investigated phytoplankton‐zooplankton trophic links in contrasting oligotrophic and eutrophic conditions. Size fractionated particulate matter (pico‐POM, nano‐POM, and micro‐POM) and zooplankton (64 to >4000 μm) composition and carbon and nitrogen stable isotope ratios were measured inside and outside the nutrient‐rich deep convection zone in the central Liguro‐Provencal basin. In winter, phytoplankton biomass was low (0.28 mg m−3) and evenly spread among picophytoplankton, nanophytoplankton, and microphytoplankton. Using an isotope mixing model, we estimated average contributions to zooplankton biomass by pico‐POM, nano‐POM, and micro‐POM of 28, 59, and 15%, respectively. In spring, the nutrient poor region outside the convection zone had low phytoplankton biomass (0.58 mg m−3) and was dominated by pico/nanophytoplankton. Estimated average contributions to zooplankton biomass by pico‐POM, nano‐POM, and micro‐POM were 64, 28 and 10%, respectively, although the model did not differentiate well between pico‐POM and nano‐POM in this region. In the deep convection zone, spring phytoplankton biomass was high (1.34 mg m−3) and dominated by micro/nano phytoplankton. Estimated average contributions to zooplankton biomass by pico‐POM, nano‐POM, and micro‐POM were 42, 42, and 20%, respectively, indicating that a large part of the microphytoplankton biomass may have remained ungrazed.
Homogeneity testing for spatially correlated data in multivariate regional frequency analysis
Authors: Šimková Tereza 
Published: July 2017

AbstractIdentification of homogeneous regions is a key task in regional frequency analysis (RFA) to obtain adequate quantile estimates for an event of interest. Recently, the frequently used univariate Hosking‐Wallis L‐moment homogeneity test was extended to the multivariate case. Multivariate L‐moments are used as a tool to define the test statistic and copula models to describe the statistical behavior of the analyzed dependent variables. To avoid drawbacks in fitting a parametric joint distribution to the data and a rejection threshold which is based on simulations, its nonparametric alternatives were also proposed. Although the simulation studies performed demonstrated the usefulness of both the parametric and nonparametric tests, the powers obtained were valid only for regions without intersite dependence. Examples from practice nevertheless demonstrate that intersite correlation may be expected for some kinds of data. To overcome the problem of cross correlation between stations, the parametric testing procedure is generalized using D‐vine copulas to model intersite dependence when generating synthetic homogeneous regions during the testing procedure. Monte Carlo simulations were performed and illustrate how intersite dependence negatively impacts the multivariate L‐moment homogeneity tests by significantly reducing their powers. The results of simulations also demonstrate the superiority of the proposed modification over both the original parametric and nonparametric procedures inasmuch as it improves the heterogeneity detection and avoids miscategorization of a region. The modified test is also applied in a case study for meteorological data in the Czech Republic.
Adaptation to flood risk: Results of international paired flood event studies
Authors: Kreibich Heidi , Di Baldassarre Giuliano , Vorogushyn Sergiy , Aerts Jeroen C. J. H. , Apel Heiko , Aronica Giuseppe T. , Arnbjerg‐Nielsen Karsten , Bouwer Laurens M. , Bubeck Philip , Caloiero Tommaso , Chinh Do T. , Cortès Maria , Gain Animesh K. , Giampá Vincenzo , Kuhlicke Christian , Kundzewicz Zbigniew W. , Llasat Maria Carmen , Mård Johanna , Matczak Piotr , Mazzoleni Maurizio , Molinari Daniela , Dung Nguyen V. , Petrucci Olga , Schröter Kai , Slager Kymo , Thieken Annegret H. , Ward Philip J. , Merz Bruno 
Published: July 2017

AbstractAs flood impacts are increasing in large parts of the world, understanding the primary drivers of changes in risk is essential for effective adaptation. To gain more knowledge on the basis of empirical case studies, we analyze eight paired floods, that is, consecutive flood events that occurred in the same region, with the second flood causing significantly lower damage. These success stories of risk reduction were selected across different socioeconomic and hydro‐climatic contexts. The potential of societies to adapt is uncovered by describing triggered societal changes, as well as formal measures and spontaneous processes that reduced flood risk. This novel approach has the potential to build the basis for an international data collection and analysis effort to better understand and attribute changes in risk due to hydrological extremes in the framework of the IAHSs Panta Rhei initiative. Across all case studies, we find that lower damage caused by the second event was mainly due to significant reductions in vulnerability, for example, via raised risk awareness, preparedness, and improvements of organizational emergency management. Thus, vulnerability reduction plays an essential role for successful adaptation. Our work shows that there is a high potential to adapt, but there remains the challenge to stimulate measures that reduce vulnerability and risk in periods in which extreme events do not occur.
Using 3‐D‐printed analogues to investigate the fall speeds and orientations of complex ice particles
Authors: Westbrook C. D. , Sephton E. K. 
Published: July 2017

AbstractThe terminal velocity vt and preferred orientations of ice particles have been investigated using 3‐D‐printed analogues sedimenting in glycerine solutions at Reynolds numbers typical of natural ice particles falling in air. Twenty‐two different particle geometries were investigated: these included both simple shapes, such as hexagonal plates, and more complex particles, such as bullet rosettes, plate polycrystals, and aggregates. Two widely used prescriptions for ice particle fall speed were tested against the new experimental data, to determine the accuracy of their predictions. We show that for open particles, such as bullet rosettes and aggregates, one of these prescriptions systematically overestimates vt, by as much as 80%.
Emerging European winter precipitation pattern linked to atmospheric circulation changes over the North Atlantic region in recent decades
Authors: Ummenhofer Caroline C. , Seo Hyodae , Kwon Young‐Oh , Parfitt Rhys , Brands Swen , Joyce Terrence M. 
Published: July 2017

AbstractDominant European winter precipitation patterns over the past century, along with their associated extratropical North Atlantic circulation changes, are evaluated using cluster analysis. Contrary to the four regimes traditionally identified based on daily wintertime atmospheric circulation patterns, five distinct seasonal precipitation regimes are detected here. Recurrent precipitation patterns in each regime are linked to changes in atmospheric blocking, storm track, and sea surface temperatures across the North Atlantic region. Multidecadal variability in the frequency of the precipitation patterns reveals more (fewer) winters with wet conditions in northern (southern) Europe in recent decades and an emerging distinct pattern of enhanced wintertime precipitation over the northern British Isles. This pattern has become unusually common since the 1980s and is associated with changes in moisture transport and more frequent atmospheric river events. The observed precipitation changes post‐1950 coincide with changes in storm track activity over the central/eastern North Atlantic toward the northern British Isles.
Remarkable separability of circulation response to Arctic sea ice loss and greenhouse gas forcing
Authors: McCusker K. E. , Kushner P. J. , Fyfe J. C. , Sigmond M. , Kharin V. V. , Bitz C. M. 
Published: July 2017

AbstractArctic sea ice loss may influence midlatitude climate by changing large‐scale circulation. The extent to which climate change can be understood as greenhouse gas‐induced changes that are modulated by this loss depends on how additive the responses to the separate influences are. A novel sea ice nudging methodology in a fully coupled climate model reveals that the separate effects of doubled atmospheric carbon dioxide (CO2) concentrations and associated Arctic sea ice loss are remarkably additive and insensitive to the mean climate state. This separability is evident in several fields throughout most of the year, from hemispheric to synoptic scales. The extent to which the regional response to sea ice loss sometimes agrees with and sometimes cancels the response to CO2 is quantified. The separability of the responses might provide a means to better interpret the diverse array of modeling and observational studies of Arctic change and influence.
Submarine landslide and tsunami hazards offshore southern Alaska: Seismic strengthening versus rapid sedimentation
Authors: Sawyer Derek E. , Reece Robert S. , Gulick Sean P. S. , Lenz Brandi L. 
Published: July 2017

AbstractThe southern Alaskan offshore margin is prone to submarine landslides and tsunami hazards due to seismically active plate boundaries and extreme sedimentation rates from glacially enhanced mountain erosion. We examine the submarine landslide potential with new shear strength measurements acquired by Integrated Ocean Drilling Program Expedition 341 on the continental slope and Surveyor Fan. These data reveal lower than expected sediment strength. Contrary to other active margins where seismic strengthening enhances slope stability, the high‐sedimentation margin offshore southern Alaska behaves like a passive margin from a shear strength perspective. We interpret that seismic strengthening occurs but is offset by high sedimentation rates and overpressure. This conclusion is supported by shear strength outside of the fan that follow an active margin trend. More broadly, seismically active margins with wet‐based glaciers are susceptible to submarine landslide hazards because of the combination of high sedimentation rates and earthquake shaking.
Triggering of volcanic eruptions by large earthquakes
Authors: Nishimura Takeshi 
Published: July 2017

AbstractWhen a large earthquake occurs near an active volcano, there is often concern that volcanic eruptions may be triggered by the earthquake. In this study, recently accumulated, reliable data were analyzed to quantitatively evaluate the probability of the occurrence of new eruptions of volcanoes located near the epicenters of large earthquakes. For volcanoes located within 200 km of large earthquakes of magnitude 7.5 or greater, the eruption occurrence probability increases by approximately 50% for 5 years after the earthquake origin time. However, no significant increase in the occurrence probability of new eruptions was observed at distant volcanoes or for smaller earthquakes. The present results strongly suggest that new eruptions are likely triggered by static stress changes and/or strong ground motions caused by nearby large earthquakes. This is not similar to the previously presented evidence that volcanic earthquakes at distant volcanoes are remotely triggered by surface waves generated by large earthquakes.
Impact of M‐solar flare‐induced solar proton event on mesospheric Na layer over Utah (41.8°N,112°W)
Authors: Bag Tikemani 
Published: July 2017

AbstractThe influence of solar proton event, induced by M‐solar flare, on the mesospheric sodium layer is studied over a midlatitude location Utah(41.8°N, 112°W) during 19 July 2012. The variation in sodium concentration (cm−3) is examined with temperature and atomic oxygen concentration obtained from NRLMSISE‐00 empirical model. In the vicinity of peak sodium concentration, the temperature shows a strong negative correlation with sodium concentration, atomic oxygen concentration shows a positive correlation with sodium concentration. An enhancement in sodium concentration is observed during the solar proton event with highest concentration at the time of maximum proton flux. The altitude of peak sodium concentration shows a downward movement with lowest altitude corresponding to the time of maximum proton flux. However, the altitude of peak sodium concentration is found in the altitude region of 85–90 km throughout the solar proton event.
Generation of rising‐tone chorus in a two‐dimensional mirror field by using the general curvilinear PIC code
Authors: Ke Yangguang , Gao Xinliang , Lu Quanming , Wang Xueyi , Wang Shui 
Published: July 2017

AbstractRecently, the generation of rising‐tone chorus has been implemented with one‐dimensional (1‐D) particle‐in‐cell (PIC) simulations in an inhomogeneous background magnetic field, where both the propagation of waves and motion of electrons are simply forced to be parallel to the background magnetic field. In this paper, we have developed a two‐dimensional (2‐D) general curvilinear PIC simulation code and successfully reproduced rising‐tone chorus waves excited from an anisotropic electron distribution in a 2‐D mirror field. Our simulation results show that whistler waves are mainly generated around the magnetic equator and continuously gain growth during their propagation toward higher‐latitude regions. The rising‐tone chorus waves are observed off the magnetic equator, which propagate quasi‐parallel to the background magnetic field with the wave normal angle smaller than 25°. Due to the propagating effect, the wave normal angle of chorus waves is increasing during their propagation toward higher‐latitude regions along an enough curved field line. The chirping rate of chorus waves is found to be larger along a field line with a smaller curvature.
Self‐consistent formation of a 0.5 cyclotron frequency gap in magnetospheric whistler mode waves
Authors: Ratcliffe H. , Watt C. E. J. 
Published: July 2017

AbstractDecades of in situ observations of whistler mode waves in Earth's magnetosphere reveal that there is frequently a gap in the spectral power at around half the local electron gyrofrequency. Recent theoretical and kinetic simulation studies have suggested that the gap arises due to the presence of temperature anisotropy in both a “warm” and a “hot” electron population, leading to two separate (and independent) regions of wave growth in frequency space. We present two‐dimensional kinetic plasma simulations using the powerful EPOCH (Extendable PIC Open Collaboration) particle‐in‐cell code that offer an alternative explanation. After an initial linear‐growth period, our simulations show self‐consistent formation of a gap feature. In most cases this arises where linear theory predicts the maximum growth rate and is associated with subtle local structuring of the hot electron distributions. This feature persists in multiple simulations with varying hot electron parameters. We discuss these results in the context of in situ observations of both waves and electron distribution functions and argue that the rapid reorganization of electron distributions in a small, but key, region of phase space during the growth of whistler mode waves naturally results in the spectral gap often observed at half the electron gyrofrequency.
Stress‐dependent permeability and wave dispersion in tight cracked rocks: Experimental validation of simple effective medium models
Authors: Sarout Joel , Cazes Emilie , Delle Piane Claudio , Arena Alessio , Esteban Lionel 
Published: July 2017

AbstractWe experimentally assess the impact of microstructure, pore fluid, and frequency on wave velocity, wave dispersion, and permeability in thermally cracked Carrara marble under effective pressure up to 50 MPa. The cracked rock is isotropic, and we observe that (1) P and S wave velocities at 500 kHz and the low‐strain (<10−5) mechanical moduli at 0.01 Hz are pressure‐dependent, (2) permeability decreases asymptotically toward a small value with increasing pressure, (3) wave dispersion between 0.01 Hz and 500 MHz in the water‐saturated rock reaches a maximum of ~26% for S waves and ~9% for P waves at 1 MPa, and (4) wave dispersion virtually vanishes above ~30 MPa. Assuming no interactions between the cracks, effective medium theory is used to model the rock's elastic response and its permeability. P and S wave velocity data are jointly inverted to recover the crack density and effective aspect ratio. The permeability data are inverted to recover the cracks' effective radius. These parameters lead to a good agreement between predicted and measured wave velocities, dispersion and permeability up to 50 MPa, and up to a crack density of ~0.5. The evolution of the crack parameters suggests that three deformation regimes exist: (1) contact between cracks' surface asperities up to ~10 MPa, (2) progressive crack closure between ~10 and 30 MPa, and (3) crack closure effectively complete above ~30 MPa. The derived crack parameters differ significantly from those obtained by analysis of 2‐D electron microscope images of thin sections or 3‐D X‐ray microtomographic images of millimeter‐size specimens.