bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Rapid and Simple Method for Fatty Acid Profiling and Determination of ω-3 Index in Red Blood Cells
Authors: Akinyemi Olufunmilola , Bruckner Geza , Johnson John , Lennie Terry A. , Hildebrand David 
Published: February 2017

Fatty acid profiling has become a very useful and effective tool in the diagnosis, prevention and treatment of several diseases with cardiovascular disease being particularly important. In order to arrive at accurate conclusions that would help promote the health of individuals plagued by such diseases, not only excellent laboratory methods are required, but also very important monitoring responses to treatment. Improvements in methods of fatty acid profiling in biological systems regarding safety of extraction, precision and time for analysis are valuable. The ω-3 index (a measure of the amount of eicosapentaenoic acid, EPA, and docosahexaenoic acid, DHA, in Red Blood Cell membranes expressed as the percent of total fatty acids) is of growing interest because it has been reported to provide prognostic information regarding the risk for heart diseases. Sodium methoxide has been widely used for the determination of ω -3 fatty acids in food samples. This study demonstrates that sodium methoxide can be used effectively in RBC fatty acid profiling and determination of the ω-3 index. Briefly, the fatty acid profiles and ω-3 index of red blood cell samples were analyzed and results compared using three different methods: a two- step extraction and methylation method described by Hara and Radin, a single step extraction and methylation method described by Harriset al.and the sodium methoxide method.Our results revealed that there were no statistically significant differences (p<0.05) between the three methods for the representative fatty acids, [16:0 (p = 0.10), 18:0 (p=0.40), 18:1(ω9) (p = 0.29), 18:2(ω6) (p = 0.95), 18:3(ω3) (p = 0.50), 20:5(ω3) (p=0.56), 22:6(ω3) (p = 0.06)] and ω-3 index (p = 0.11) except for 20:4(ω6), (P = 0.02). In conclusion, we show that sodium methoxide can be used effectively in a one-step extraction and methylation procedure for high throughput analysis of fatty acids in red blood cell membranes. It is rapid (10 minute extraction and methylation), simple, safer than and as accurate as other commonly reported methods.
A Prospective Cohort Study of the Therapeutic Patterns, Challenges and Outcomes of Paediatric Femoral Fractures in a Cameroonian Tertiary Center
Authors: Tochie Joel Noutakdie , Guifo Marc Leroy , Yamben Marie-Ange Ngo , Moulion Roger , Farikou Ibrahim 
Published: February 2017

Background:
Knowledge of the therapeutic patterns, challenges and outcomes of treatment of paediatric femoral fractures (PFF) helps to better choose the ideal therapeutic modality which is still controversial. However, this data is scarce in the sub-Saharan African literature.

Objective:
To determine the therapeutic patterns, treatment challenges and outcomes of treatment of PFF in a tertiary care centre in Cameroon.

Method:
We conducted a prospective cohort study of all consenting consecutive cases of femoral fractures in patients younger than 16 years managed between 2011 and 2015 at the surgical unit of Yaoundé University Teaching Hospital, Cameroon. We analysed demographic data, injury characteristics, fracture patterns, treatment details, therapeutic challenges and outcomes of treatment at 12 months using Flynn’s criteria.

Results:
We enrolled 30 femoral fractures from 29 children with mean age was 4.2 ± 3.3 years. The male gender, diaphyseal locations and spiral fracture lines were predominant. Main mechanisms of injury were accidental falls, road traffic accidents and game injuries. Fracture management entailed 12 tractions followed by casting, 10 casting alone, four closed reductions followed by casting, two cannulated screw fixations, one pin fixation and one external fixation. The mean duration of consolidation was 10.3 ± 3.9 weeks. The outcome was rated excellent in 28 cases. Limited resources precluded fluoroscopy use, proper anaesthetic management, early rehabilitation and patient-parent satisfaction.

Conclusion:
Conservative management of PFF yields a good outcome in our setting. However, an improvement in surgical, radiology and anaesthetic infrastructure is needed for optimal PFF care.
Concurrent Validity of the Computer-assisted Structured Diagnostic Interview (CASDI) for Children and Adolescents Aged 8-18 Years Old
Authors: Giannakopoulos George 
Published: February 2017

Background:Making a diagnosis of a particular mental disorder in children and adolescents can be a challenging or overwhelming task for clinicians and researchers, with each step of a DSM-5 based diagnostic procedure necessitating a practical use of time to gather appropriate information.Objective:To assess concurrent validity of the Computer-Assisted Structured Diagnostic Interview (CASDI), a newly devised, fully structured interview which encompasses categorical and dimensional approaches and automatically navigates the interviewer, through computerized decision trees (algorithms), in a specified probing system.Method:A total of 258 children and adolescents (46.51% boys) aged 8-18 years (Mean±SD: 12.66±2.73) and their parents were recruited from a community sample. For each pair of child-parent, the child and one parent were interviewed separately by an interviewer using the CASDI and by a second blind interviewer using the DSM-5 Pediatric Diagnostic Interview one week after the CASDI administration. Validity indicators (sensitivity, specificity, positive and negative likelihood ratios, and positive and negative predictive values for 12-month diagnoses were calculated.Results:The CASDI had sensitivity above 70% for Neurodevelopmental Disorders, Schizophrenia Spectrum and Other Psychotic Disorders, Depressive Disorders, Anxiety Disorders, Obsessive-Compulsive and Related Disorders, Trauma- and Stressor-Related Disorders, Somatic Symptom and Related Disorders, Feeding and Eating Disorders, Elimination Disorders, Sleep-Wake Disorders, Gender Dysphoria, Disruptive, Impulse-Control, and Conduct Disorders, Substance-Related and Addictive Disorders and below 50% for Bipolar and Related Disorders and Dissociative Disorders.Conclusion:The observed validity indicators suggest that the CASDI can be potentially used to accurately diagnose child and adolescent mental health disorders for research and clinical purposes. Its use in special populations, such as hospitalized or institutionalized children and adolescents, deserves further study.
Corrosion Processes Relevant to the Integrity of Oil and Gas Facilities1
Authors: Langøy Morten A. , Hörnlund Erik , Næss Ole Jacob , Hinderaker Rolf H. 
Published: February 2017

The Petroleum Safety Authority (PSA) Norway will set the terms for and follow up that players in the Norwegian petroleum industry maintain a high level of health, safety and the environment and emergency preparedness, and thereby contribute to creating the highest possible value for society. Ensuring good material selection process and structural integrity is an important effort where different corrosion forms are of concern and corrosion protection measures of interest, especially in respect to major accidents.PSA addresses corrosion in rules and regulations, requiring “robust material selection”, with reference to international standards and guidelines. The operators addressing and monitoring of the corrosion effects on the process and structural integrity by incident reporting, reviews and site audits are the key tools for PSA in assessing the corrosion challenges and control in the industry.It is of paramount importance to avoid major accidents. The subject of this paper is to address the challenges with material degradation in ageing structures, and the challenges associated with life extension considerations. Corrosion plays a major role in this respect; especially PSA is concerned with corrosion under insulation (CUI). This paper presents some of our work in these areas.
Empowerment-Based Diabetes Self-Management Education to Maintain Glycemic Targets During Ramadan Fasting in People With Diabetes Who Are on Conventional Insulin: A Feasibility Study
Authors: Eid Yara M. , Sahmoud Sahar I. , Abdelsalam Mona M. , Eichorst Barbara 
Published: February 2017

Objective.
This study aims to assess the feasibility of promoting safe Ramadan fasting through diabetes self-management education (DSME) and to determine the effect of such education on hypoglycemic episodes.

Design and methods.
This prospective study included subjects attending Ramadan reinforcement sessions for participants in the Educational Program for People with Diabetes (EPPWD) at the Ain-Shams University Diabetes Center in Cairo, Egypt. The DSME sessions started 2–3 weeks before Ramadan and included one experimental fasting day during the first week and one during the second week. Participants’ A1C and serum fructosamine levels were measured before and after Ramadan, and they completed weekly self-monitoring of blood glucose (SMBG) logs.

Results.
Among 21 participants who were intending to fast for Ramadan, 14 completed the program. Their mean A1C was 6.7 ± 1.6%, and SMBG results showed a statistically nonsignificant difference in mean blood glucose levels before and after Ramadan (123.84 ± 39.96 and 123.84 ± 25.92 mg/dL, respectively; P &gt;0.05). Serum fructosamine after Ramadan declined by 10% from pre-Ramadan levels. The mean number of hypoglycemic events before Ramadan was 3 ± 1.04, which declined to 1.4 ± 0.5 during Ramadan. Differences between group 1 (those without hypoglycemia, n = 8) and group 2 (those with hypoglycemia, n = 6) were nonsignificant for all variables, including A1C.

Conclusion.
Ramadan fasting is feasible for people with diabetes who are on a multiple daily injection insulin regimen and participate in the EPPWD. The number of hypoglycemic events per month declined with the attainment of DSME.
IMPLEMENTASI QUALITY FUNCTION DEPLOYMENT DALAM KUALITAS LAYANAN FAKTOR-FAKTOR MOTIVASI KEPADA PELANGGAN INTERNAL PADA BALITBANG KOTA SURABAYA
Authors: Soedjono Soedjono 
Published: February 2017

Nowadays rumor spreads among non managerial officials or commonly called internal customers of being unsatisfied for the quality service of motivation factors provided by the organization of the Research and Development Board of the City of Surabaya. The quality or the value of service expected by the officials will positively or negatively influence the work satisfaction, and the work satisfaction will influence the quality of the individual performance, then the quality of the individual performance will influence the quality of organization performance. Therefore, efforts to identity the quality of the work satisfaction which is expected and enjoyed by the officials are very important in trying to minimize the gap. The method of analysis employed here is Quality Function Deployment, one of the planning instrument to apply the Tobel Quality Management, the main objective of which is to determine the interval customers, i.e. the planning method of the service development which specializes on the needs and wants of the customers, by conducting survery on the internal customers satisfactionThe results of the study can be expressed in the following. (1) The highest expected value of the service satisfaction is the achievement variable of 4-91, but the real service value is 3.30. Thus the gap value is 1.61, higher than 1 (>1), which means that it is not satisfactory. This is because at this time, the organization doesn’t care much of the officials achievement. (2) The lowest expected value of the variable is 3.96, that is for the techical supervisio, but the gap value is 0,83, lower than 1 (<1), that means unsatisfactory. (3) The variables with satisfaction gap value higher than 1 (>1) which means unsatisfactory can be stated here in the order beginning with the highest = interpersonal relation = 1.82, advancement = 1.78, achievement 1.61, working condition = 1.48, company policies and administration 1.29, attractiveness = 1.18, recognition = 1.09 and responsibility = 1.3 (1.037). Thus those variables should be observed by the organization in order to undergo changes to minimize the gap between expectation and satisfaction that exists now.
AUDIT FORENSIK OLEH AKUNTAN PUBLIK SEBAGAI SALAH SATU BUKTI PERKARA DI PENGADILAN
Authors: Ngumar Sutjipto 
Published: February 2017

Audit Forensic is a falseness auditing, connected with criminal case and an audited with falseness connected with governmental financial and other object including corruption as a special criminal result. As the most cases corruption in the world, cleaning in the whole level of corruption, collutin and Nepotism (KKN), the goverment of Indonesia ask for assistance to Public Accountant to take Forensic Auditing for falseness done by government and private apparatures.This paper presented to know how far the special audit (Forensic) for financial can be used as a falseness evidence in the law court. Forensic Audit Report presented by Public Accountant, the audit procedures have been conformed with auditing standard and investigate’s procedures arranged with Law Articles (KUHAP). By Joint Venture between Public Accountant and investigator the falseness action which can not been detected by auditing standard procedures the falseness like Collutions, and Nepotisme can be broken – up.Public Accountant as an expert witness has been executed his job, prepared in Forensic Audit Statement, which content with unlawful actions by the Accused, it can be used as an evidence’s tools in the law – court.
PENTINGNYA REFORMASI KEBIJAKSANAAN PEMERINTAH DALAM PENGHEMATAN BELANJA NEGARA
Authors: Setyodarmodjo Soenarko 
Published: February 2017

Many people say, whether domestic or abroad, that Indonesia is one of the rich countries in the world. But, in the reality now Indonesia has a national debt to the foreign states of about US$ I 37 billions. That is amazing, it has been happening, due to the malpractice and inadequate policy making and public management of the "new order government "reigned by Suharto. Now, the Indonesian people inherited the obligation to pay back the national debt. Certainly, the effect to the public finance now is apprehensivible. The deficit financing will appear year by year with the hope that the Indonesian people will be able to get out of financial crises in the coming years for the development of the country.The deficit in the State budget of the year 2002 about Rp. 42 trillion is actually as like an Indonesian proverb: "Besar Pasak daripada Tiang", that litteral/y means: the pin-is too bigfor the mast".However, we must have the solution to overcome that deficit in a prudent way so that it is not hampering the development of the economic and social life in Indonesia.Therefore, it has been recommended that the selling of the asset of the state anterprises based on the natural resources must be taken into accurate consideration in relation with the future. We must remember, that "natural resources factor" is one of the natural determinant of powers of a State. We still have another way by economizing the expenditure particularly to evaluate the policies which have been arranged legally by unjust policy making. The related inappropriate policies must be revised or reformulated. The double income of pension of many ex-government and ex-political officials must be eliminated. It is an injustice.The priority of the several normative political activities must be effectively arranged, while we now are very busy with the strategic and operational planning of the implementation of the national policy. So, the plenary session of the People's Consultative Assembly in November 200I will not be effective and wasting a huge of money for this session. The economizing of public financing is necessary.The other way to get some more income in the revenue of the budget, is that the government has the courage to make a policy decision to take the authority in the management of the foundations which have been supervised and managed by Suharto 's family and their comrades. All of the assets in the foundations have something as a purpose for the social welfare or public interest and economical recovery in the society. So, the use of the money or assets of the foundations to cover the deficit in the state budget is reasonable.
PENGARUH STOCK SPLIT TERHADAP PERUBAHAN HARGA SAHAM YANG LISTED DI BURSA EFEK SURABAYA
Authors: Sugiyono Sugiyono 
Published: February 2017

Stock Split merupakan kebijakwnaan yang ditempuh perusahaan untuk memperoleh tanggapan positip dari imestor, dengan split diharapkan volume perdagangan saham meningkat, dengan demikian return pemenang saham meningkat juga. Untuk membuktikan, maka diperlukan penxamatan pada sekitar hari pemecahan saham atau jendela pengamatan, yang meliputi data closing price, index harga saham gabungan, dan trading volume activity, serta jumlah saham yang beredar untuk setiap perusahaan anggata sampel. Kemudian dilakukan perhitungan-perhitungan terhadap Actual return, Market return, Persamaan regresi single index model, uji sign fikansi persamaan regresi, Hxpected return, Abnormal return, Rata-rata abnormal return, Likuiditas saham.Pengujian dilakukan dengan one sample test maupun dengan gmup sample test terhadap Averafge Abnormal return, Likuiditas saham, maupun Average Actual return.Hasil pengujian menunjukan: investor tidak mempero/eh abnormal return, abnormal return soma antara sebelum dan sesudah split likuiditas saham meningkat pada hari-hari tertentu sesudah split, likuiditas perdagangan saham sesudah split lebih besar dibanding sebelum split, average actual return tidak herheda dengan nol, actual return sesudah split sama dengan sebelum split.
ANALISIS VARIABEL-V ARIABEL PEMBEDA KEPUTUSAN KONSUMEN BERKUNJUNG KE TAMAN AGROWISATA BATU DAN AGROWISA TA PT PERKEBUNAN NUSANTARA XII LAWANG
Authors: Rahayu Rahayu , Budiyanto Budiyanto 
Published: February 2017

Industri pariwisata merupakan salah satu produk andalan untuk memperoleh devisa negara, untuk itu pengembangannya diharapkan dapat memacu pertumbuhan perekonomian Indonesia. Sektor pariwisata merupakan sektor industri yang komplek yang didalamnya juga terdapat industri lainnya seperti: industri rumah tangga, hotel, makanan, kerajinan dan lain-lain. Kondisi ini dapat memberikan suatu gambaran bahwa sektor pariwisata harus dikembangkan mengingat banyaknya sumber wisata yang ada.Meningkatnya permintaan produk rekreasi alam hutan disebabkan banyak faktor, oleh karena itu setiap obyek wisata harus mempunyai ciri khusus sehingga banyak menarik pengunjung. Pengembangan setiap obyek wisata dapat melalui faktor product, place, price, promotion, physical evidence, process dan personal traits.Tujuan dari penelitian ini adalah untuk mengetahui apakah faktor produk, harga, promosi, tempat, proses, personal trait dan physical evidence merupakan faktor pembeda keputusan konsumen berkunjung ke taman Agrowisata Batu dan Agrowisata PTP Nusantara XII Lawang dan untuk mengetahui jaktor pembeda dominan diantara faktor produk , harga, promosi, tempat, proses, personal trait dan physical evidence terhadap keputusan konsumen berkunjung ke taman Agrowisata Batu dan Agrowisata PTP Nusantara XII lawang.Hasil analisis menunjukkan bahwa variabel produk, harga, promosi, tempat, proses, personal trait dan physical evidence signijikan membedakan keputusan konsumen berkunjung ke taman Agrowisata Batu dan Agrowisata PTP Nusantara XII Lawang terbukti benar. Hal ini dapat dilihat dari nilai probabilitas sebesar 0,000 yang mana nilai tersebut berada dibawah 5% dan nilai wilks lamda sebesar 0,355. Berdasarkan nilai square cannonical correlation sebesar 0,644 atau 64,4% maka nilai tersebut
MANAJEMEN LABA PADA PERlJSAHAAN BERMASALAH
Authors: Amanah Lailatul 
Published: February 2017

The objective of this study was to examine earning management practice to companies with persistencely loss. This study employs accruals model especially discretionary accruals from Jones model to measure earnings management. This study employs t-test to test of hypothesis that the troubled companies have more abnormal accruals than non­ troubled companies. Contrary to hypothesis this reseach provide evidence both the troubled companies and nontroubled companies have managed earnings to reported earnings upward. Discretionary accruals mean to troubled companies and nontroubled companies were 0.305 and 0. 190 respectively. Mean d!ffrences of abnormal accruals is not siqnificant to both troubled companies and nontroubled companies.
Influence of atomic processes on charge states and fractions of fast heavy ions passing through gaseous, solid, and plasma targets
Authors: Tolstikhina I Yu , Shevelko V P 
Published: February 2017

Abstract
An overview of experimental data and theoretical methods is given for charge-changing processes with ion beams passing through gaseous, solid, and plasma targets. The main focus is on electron capture and electron loss processes involving heavy many-electron ions (like Ar
q+
, Kr
q+
, Pb
q+
, W
q+
, U
q+
) at relatively large and relativistic ion energies E = 50 keV/u − 50 GeV/u, including multielectron processes, which increase the total cross sections to about 50% or more. A large part of the paper is devoted to consideration of the stopping power of matter—the basic quantity characterizing kinetic energy losses of ions due to interactions with particles in matter. The electron capture processes for heavy ions colliding with atoms at low energies E < 10 eV/u and the arising isotopic effect are briefly discussed. The formation dynamics of charge-state fractions and average equilibrium charges in the ion beams interacting with medium particles are considered on the basis of the balance rate equations, including the creation of equilibrium charge-state fractions and average charges, an equilibrium target thickness and ion beam average charge, etc. A short description of the computer programs ETACHA, GLOBAL, CHARGE, and BREIT for calculating the charge-state fractions as a function of the target thickness is given, and some applications directly using charge-state fractions, e.g., in the detection of superheavy elements and in solving problems in laboratory and astrophysical plasmas, are considered. All physical processes and effects touched upon in the paper are explained in terms of atomic physics using the radiative and collisional characteristics of heavy many-electron ions interacting with electrons, atoms, ions, and molecules.
Impact of ITPA Gene Polymorphisms on the Risk of Ribavirin-Induced Haemolytic Anaemia using Interferon-Free Antivirals for Chronic Hepatitis C
Authors: Esposito Isabella , Benítez-Gutiérrez Laura , Treviño Ana , Arias Ana , Citores Maria Jesus , Requena Silvia , Soriano Vicente , Cuervas-Mons Valentín , De Mendoza Carmen 
Published: February 2017

Background Single nucleotide polymorphisms (SNPs) at the ITPA gene are associated with haemolytic anaemia in chronic hepatitis C patients treated with pegylated interferon-ribavirin (RBV). Information in patients treated with interferon-free, direct-acting antivirals (DAA) is scarce. Methods Median haemoglobin (Hb) levels were compared at baseline and at week 4, when ribavirin concentration achieves steady state, in all consecutive chronic hepatitis C patients treated with oral DAA plus RBV at our clinic. Results Median Hb drop in 55 patients was greater in rs1127354-CC than -CA/AA (1.8 versus 0.7 g/dl; P=0.029), and in rs6051702-AA than -AC/CC carriers (2.2 versus 1.1 g/dl; P=0.016). Eleven (20%) patients experienced severe anaemia, defined as Hb drop >3 g/dl or to <10 g/dl. All of them were rs6051702-AA. Conclusions Baseline testing of rs6051702 may identify the subset of patients at greatest risk for RBV-induced anaemia using interferon-free hepatitis C therapies.