bluuebunny/crossref_metadata_2025_split huggingface dataset:
CD44 Signaling Mediates High Molecular Weight Hyaluronan-Induced Antihyperalgesia
Authors: Ferrari Luiz F. , Khomula Eugen V. , Araldi Dioneia , Levine Jon D. 
Published: November 2017

We studied, in male Sprague Dawley rats, the role of the cognate hyaluronan receptor, CD44 signaling in the antihyperalgesia induced by high molecular weight hyaluronan (HMWH). Low molecular weight hyaluronan (LMWH) acts at both peptidergic and nonpeptidergic nociceptors to induce mechanical hyperalgesia that is prevented by intrathecal oligodeoxynucleotide antisense to CD44 mRNA, which also prevents hyperalgesia induced by a CD44 receptor agonist, A6. Ongoing LMWH and A6 hyperalgesia are reversed by HMWH. HMWH also reverses the hyperalgesia induced by diverse pronociceptive mediators, prostaglandin E2, epinephrine, TNFα, and interleukin-6, and the neuropathic pain induced by the cancer chemotherapy paclitaxel. Although CD44 antisense has no effect on the hyperalgesia induced by inflammatory mediators or paclitaxel, it eliminates the antihyperalgesic effect of HMWH. HMWH also reverses the hyperalgesia induced by activation of intracellular second messengers, PKA and PKCε, indicating that HMWH-induced antihyperalgesia, although dependent on CD44, is mediated by an intracellular signaling pathway rather than as a competitive receptor antagonist. Sensitization of cultured small-diameter DRG neurons by prostaglandin E2is also prevented and reversed by HMWH. These results demonstrate the central role of CD44 signaling in HMWH-induced antihyperalgesia, and establish it as a therapeutic target against inflammatory and neuropathic pain.SIGNIFICANCE STATEMENTWe demonstrate that hyaluronan (HA) with different molecular weights produces opposing nociceptive effects. While low molecular weight HA increases sensitivity to mechanical stimulation, high molecular weight HA reduces sensitization, attenuating inflammatory and neuropathic hyperalgesia. Both pronociceptive and antinociceptive effects of HA are mediated by activation of signaling pathways downstream CD44, the cognate HA receptor, in nociceptors. These results contribute to our understanding of the role of the extracellular matrix in pain, and indicate CD44 as a potential therapeutic target to alleviate inflammatory and neuropathic pain.
The Theory of Intersectionality: A New Lens for Understanding the Barriers Faced by Autistic Women
Authors: Saxe Amanda 
Published: November 2017

While disabilities studies scholars have already taken a great step forward in integrating the theory of intersectionality, progress is still required. Many theoretical and empirical disability studies papers operationalize disability in a vague and all-inclusive manner. Although it is important to research disability in a global way, it is just as important to regard the more specific experiences of disability. The study of specific disabilities and the barriers that are faced by those who have them is critical since living with one type of disability can lead to very different experiences as compared with having a different disability (Hirschmann, 2012). In addition to adding Autism to the discussion of intersectionality within disability studies, it is critical to include a disability studies perspective to other fields of research in order to successfully incorporate an intersectional framework.
Syntactic discontinuities in Latin – A treebank-based study
Authors: Haug Dag 
Published: November 2017

Syntactic discontinuities are very frequent in classical Latin and yet this data was never considered in debates on how expressive grammar formalisms need to be to capture natural languages. In this paper I show with treebank data that Latin frequently displays syntactic discontinuities that cannot be captured in standard mildly context-sensitive frameworks such as Tree-Adjoining Grammars or Combinatory Categorial Grammars. I then argue that there is no principled bound on Latin discontinuities but that they display a broadly Zipfian distribution where frequency drops quickly for the more complex patterns. Lexical-Functional Grammar can capture these discontinuities in a way that closely reflects their complexity and frequency distributions.
США: безответственная риторика и вероломная политика
Authors: Ильин Алексей Николаевич 
Published: November 2017

<p>В статье обосновывается, что вербализуемая американскими лидерами политическая пропаганда выступает наиболее наглядным образцом риторики двойных стандартов, лицемерия и лжи. Американская политика опирается на эту легитимирующую ее риторику. Безответственность и вероломство — характерные черты американской риторики и политики. Автором приведено достаточно много примеров высказанных американскими пропагандистами идеологем и действий США на мировой арене, доказывающих этот тезис. Описаны как геополитические, так и экономические случаи. Анализируется внешняя политика США по отношению к России, Ираку, Сирии, Грузии и Украине.</p><p> </p>
Concomitant presence of bilateral nevus of Ota with unilateral nevus of Ito and halo nevus: a rare association
Authors: Salunke Aarti S. , Nagargoje Mahendra V. , Chavan Ravindranath B. , Bansal Nilima M. 
Published: November 2017

<p>Nevus of Ota is dermal melanocytosis, generally presents as blue-black or gray-brown patchy diffuse pigmentation. Most commonly occurs unilaterally on face in areas innervated by the first and second divisions of trigeminal nerves. Bilateral involvement and oral mucosal involvement can occur, but as a rare manifestation. Nevus of Ota may be very rarely associated with the nevus of Ito and other extra cutaneous features. The halo nevus may be seen in congenital or acquired melanocytic nevi. Presence of halo nevus in conjunction with two different dermal nevi is not reported till date. We are reporting 19 year old female presented with bilateral Nevus of Ota with oral mucosal involvement and associated nevus of Ito and halo nevus.</p>
AKTIVITAS MUI DALAM PERKEMBANGAN KEHIDUPAN KEAGAMAAN DI SURAKARTA TAHUN 1975-2015
Authors: Maftuh Hasan 
Published: November 2017

This research was developed using the approach of social history that refers to events or socialreligious reality in society and aims to clarify the role of the Assembly of the Ulama Indonesia (MUI) of Surakarta in responding to the change or the development of the social-religious life in community. The results of this research demonstrates that (1) the Assembly of Indonesia of Surakarta Scholars played full, in the Islamic community especially. For example, they provide advice, counsel and fatwa guidance asked or not. (2) in the social reality, they respond to the social conflict. The responses enacted by the scholars are presented into three terms, among others; attempting to be a pioneer of the peace at the time of the riots, giving social advocacy in form of action and being a mediator when conflicts arose disagreements.
Soybean Productivity as Affected by Raised Seedbeds Under Dry Environments
Authors: Hoppe Aaron R. , Mehring Grant H. , Kandel Hans 
Published: November 2017

Background:
Raised seedbeds may be a practice for reducing waterlogging in the rooting zone in soils of the Red River of the North Valley (RRNV). However, it was not known if there would be a negative yield effect of raised beds in drier environments.

Aims / Method:
The objectives of this research were to evaluate soybean [Glycine max (L.) Merr.] response to early season iron deficiency chlorosis (IDC), agronomic characteristics, and productivity when grown on raised seedbeds compared with flat seedbeds. Soybean grain yield on raised seedbeds, averaged across six drier environments in 2012, was similar to flat seedbeds. Although grain yield did not increase on raised seedbeds, grain yield was not reduced in a dry year. Across environments there were no differences in vigor, IDC, canopy closure, plant height, thousand kernel weights, seed protein or oil content, number of seeds or pods per plant, or grain yield comparing raised with flat seedbeds. At the Rothsay environment, there was more IDC with flat seedbeds compared with raised beds. Soybean cultivars significantly differed in their IDC response and in most yield components measured. Averaged across hour of day, soil temperature was significantly higher in the raised seedbed treatments at Fargo and Hitterdal by 0.4 and 0.8 °C, respectively. When averaged across two cultivars and environments, soybean root mass was 0.37 g root-system-1 higher on raised seedbeds.

Result:
Raised seedbeds may be a useful tool to manage IDC and improve soybean productivity in the RRNV, and do not reduce grain yield in environments with below average moisture.
<i>Jerusalém</i> de Gonçalo M. Tavares: romance-investigação sobre o mal
Authors: Martins Celina Maria 
Published: November 2017

O romance Jerusalém é uma reflexão profunda sobre o mal que se propaga como uma pulsão destruidora, revestindo os dispositivos disciplinares do poder-saber que alienam. Baseado na pedagogia da catástrofe de Sloterdijk e na intertextualidade que articula a reescrita do campo de concentração nazista e da Bíblia, o texto interroga a evolução do horror e o enigma da esquizofrenia de Mylia, que desconstrói os fundamentos da psiquiatria, na esteira de Foucault. Ganhando os contornos do ensaio, a ficção recorre ao pensamento de Arendt para criar consciência crítica no leitor. A loucura é a alegoria da decadência dos valores éticos e a lucidez de uma demanda plural de significado a partir da afirmação da memória criadora do passado. ---DOI: http://dx.doi.org/10.22409/abriluff.2017n19a422
Uma edição crítica de Sérgio Nazar David: <i>Almeida Garrett – correspondência para Rodrigo da Fonseca Magalhães</i>
Authors: Fialho Irene 
Published: November 2017

Livro resenhado:David, Sérgio Nazar. Almeida Garrett – Correspondência para Rodrigo da Fonseca Magalhães. Lisboa: Imprensa Nacional – Casa da Moeda, 2016, 327 pp. ---DOI: http://dx.doi.org/10.22409/abriluff.2017n19a431
Breve notícia sobre um manuscrito autógrafo de Almeida Garrett: outra versão de um poema de <i>Folhas caídas</i>
Authors: Comandulli da Cunha Ana Cristina 
Published: November 2017

Relato do achado de um manuscrito autógrafo de Almeida Garrett, em espólio de António Feliciano de Castilho. ---DOI: http://dx.doi.org/10.22409/abriluff.2017n19a440
The Thaksin Shinawatra Group: A Study of the Relationship between Money and Politics in Thailand
Authors: Pathmanand Ukrist 
Published: November 2017

Thaksin Shinawatra is a successful Thai business tycoon who
has become extremely wealthy within the last fifteen years from
investment in telecommunications and lately also in mass-transit
infrastructure. He entered politics in the mid-1990s and became
a party leader and minister in several governments.
Through a study of Thaksin's business career and his political
involvement I intend to illustrate how Thai politics functions in
practice, as well as to highlight the intimate links between
money and politics in Thailand, particularly in the telecommunications
sector. During the economic boom the telecommunications
sector was characterised by substantial profits and stiff
competition, but after the economic crisis in July 1997 the Thai
telecoms firms sustained heavy losses. In a surprise move the
two biggest telecommunications conglomerates-Shinawatra
and Charoen Phokapand-announced that they would merge
some of their telecommunications firms, thereby creating one of
the biggest concentrations of assets in Thailand and at the same
time a de fact0 monopolisation of tlie telecommunications
market. As if that were not enough, Shinawatra, together with
his former arch-rival, has launched a new political party-Thai
Rak Thai [Thai loves Thai]. This move may have profound
implications for the development of Thai politics.'
Confucianism, the Idea of Min-Pen, and the Democracy
Authors: Nuyen A. T. 
Published: November 2017

With few exceptions, it is believed that Confucianism is incompatible
with democracy. The 'incompatibility thesis' has
attained the status of near orthodoxy. It is shared by commentators
who are hostile as well as those sympathetic to Chinese
culture generally and to Confucianism in particular. The arguments
for incompatibility typically stress the differences between
on the one hand 'democratic values' such as liberty,
equality and plurality, and on the other 'Confucian values' such
as duty, responsibility and loyalty. Having challenged the arguments
for incompatibility by showing that the differences
between so-called democratic values and Confucian values are
in fact greatly exaggerated, the paper proceeds to discuss the
significance of the Confucian idea of min-pen (or min-ben,
people as roots). The aim is to show that philosophical Confucianism
is not only not an obstacle to democracy but could well
be the foundation thereof. The argument will then be further
reinforced by revisiting the old 'modernization thesis.'
Confección del plan de trabajo del especialista de pedagogía terapéutica: un ejemplo práctico
Authors: Torres González José Antonio , Colmenero Ruiz María Jesús , Hernández Fernández Antonio 
Published: November 2017

La realidad educativa de la que partimos exige al maestro de pedagogía terapéutica la elaboración de un Plan de Trabajo, entendido éste como modelo sistemático de actuación pública o privada, que se elabora anticipadamente para dirigirla y encauzarla. La realización del Plan de Trabajo surge de la necesidad de planificar las actuaciones que se vayan a llevar a cabo en el centro en relación a la Atención a la Diversidad desarrollándose en cada uno de los puntos. Desarrollaremos en este artículo la estructura organizativa para atender a la diversidad. Especificaremos las actuaciones de planificación, coordinación, asesoramiento, previsión y elaboración de material que será necesario para crear una escuela integradora de necesidades y no limitadora de oportunidades. En estas actuaciones se concretarán los lazos de unión entre toda la Comunidad Educativa, estrechándose la colaboración entre familia, escuela, servicios externos y la sociedad en general. Nuestro Plan de Trabajo se concretará para Lucía, una alumna con una serie de cualidades que le hacen ser “especial”. Todo lo nombrado se concretará en quince Unidades Didácticas de marcado carácter curricular que serán adaptadas a las características que presenta Lucía.
Estudio bibliométrico de las tesis de pregrado de la Carrera Profesional de Enfermería de la Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas
Authors: Leon Montoya Gladys Bemardita , Saavedra Chinchayan María Esther 
Published: November 2017

<p>La presente investigación cuantitativa - descriptiva de revision documental tuvo como objetivo analizar las tesis de pregrado de la Carrera Profesional de Enfernería de la Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, identificando indicadores bibliométricos de producción, visibilidad y colaboración. La poblacion estuvo conformada por 124 tesis ejecutadas en el periodo 2007 - 2013. En la ficha de recolección de información bibliométrica se recogió el año de registro y sustentación, tipo de investigación, número de variables, tamaño de muestra, diseño metodológico, prueba estadística, relación del tema con el quehacer de enfermería y las prioridades sanitarias de la región; número de referencias bibliográficas; autoría de los instrumentos e instituciones y lugares donde se desarrollaron las investigaciones. Se encontró que en el año 2012, se registraron y sustentaron la mayor cantidad de tesis, el 91,7% son de tipo cuantitativo y el 49,1% univariable. Referente al tamaño de la muestra, de los cuantitativos, el 36.3% tienen una muestra menor a 50 unidades y los cualitativos entre 6 a 10 informantes; el 85,4% son descriptivos y el 50,9% utilizo la distribucion de frecuencia como prueba estadistica; el 75% de la temática de investigación no corresponden al quehacer de enfermería y el 81,5% no se relacionan con los problemas prioritarios de la región; la mayoría en sus referencias bibliográficas mencionan libros y sitios en la red, sólo el 11% de investigadores utilizaron instrumentos validados por otros investigadores y el 35,4% de trabajos fueron realizados en los hospitales de la región. Se concluye que la producción de tesis de pregrado ha ido en aumento, la mayoria no corresponde al quehacer de enferrnería y no estan relacionados con los problemas prioritarios de la región; además, las fuentes más usadas son libros y sitios en red y pocos estudios hacen uso de instrumentos validados.</p>
Desciudadanización y estado de excepción
Authors: Moreno Hernández Hugo César 
Published: November 2017

El artículo analiza la relación entre el momento actual del sistema de sociedad y la producción de segmentos de población criminalizada, ya sea por migraciones o acciones delictivas. Siguiendo las propuestas de Giorgio Agamben, se observa que el estado de excepción y el campo (de detención, concentración, centro de internamiento, prisión preventiva, etcétera), así como la producción de vida desnuda o nuda vida (aquí visto como desciudadanización), se han convertido en los pilares que sostienen al Estado como institución. Esto se puede observar en las legislaciones que ilegalizan cruzar fronteras, así como en legislaciones internas que criminalizan y producen formas desciudadanizantes para tratar a la población excedente y problemática con leyes de mano dura.
Evaluación e identidad profesional del profesor ¿Un juego de espejos rotos?
Authors: Galaz Ruiz Alberto 
Published: November 2017

El objetivo del estudio es analizar los impactos de la política de Evaluación Docente en la identidad profesional de los profesores. La identidad profesional es definida como el concepto de Sí en relación con el trabajo y como el resultado de una construcción personal, social y contextual con profundas incidencias en la práctica y adhesión a las políticas e innovaciones. A través de entrevistas se han recogido las narrativas de dos profesores evaluados. Bajo la técnica del análisis de contenido se han calificado y cuantificado las relaciones categoriales y subcategoriales. Los resultados identifican las apreciaciones desarrolladas sobre el Sistema de Evaluación y los impactos en la identidad. También permiten discutir sobre su pertinencia y el compromiso que suscita en los profesores.
Travesías de un pensar constante. La formulación de América Latina como objeto de conocimiento
Authors: López Nájera Verónica Renata 
Published: November 2017

En este artículo propongo una caracterización en dos momentos de la trayectoria del pensamiento crítico latinoamericano. En el primero, se reconoce el paso del pensamiento hacia la teoría, y sus rasgos característicos, a partir de los paradigmas que la propia reflexión genera. El segundo momento es consecuencia de las modificaciones que implica para la reflexión social el periodo de dictaduras militares en la región. Esta nueva etapa se caracteriza por la centralidad de la perspectiva decolonial. También reviso la propuesta del patrón de dominación modernocolonial a la luz de las nuevas tendencias del pensamiento crítico. Finalmente, señalo la importancia de los movimientos sociales como generadores de conocimiento.
Voice and swallowing outcomes following reoperative anterior cervical discectomy and fusion with a 2-team surgical approach
Authors: Erwood Matthew S. , Walters Beverly C. , Connolly Timothy M. , Gordon Amber S. , Carroll William R. , Agee Bonita S. , Carn Bradley R. , Hadley Mark N. 
Published: November 2017

OBJECTIVEDysphagia and vocal cord palsy (VCP) are common complications after anterior cervical discectomy and fusion (ACDF). The reported incidence rates for dysphagia and VCP are variable. When videolaryngostroboscopy (VLS) is performed to assess vocal cord function after ACDF procedures, the incidence of VCP is reported to be as high as 22%. The incidence of dysphagia ranges widely, with estimates up to 71%. However, to the authors’ knowledge, there are no prospective studies that demonstrate the rates of VCP and dysphagia for reoperative ACDF. This study aimed to investigate the incidence of voice and swallowing disturbances before and after reoperative ACDF using a 2-team operative approach with comprehensive pre- and postoperative assessment of swallowing, direct vocal cord visualization, and clinical neurosurgical outcomes.METHODSA convenience sample of sequential patients who were identified as requiring reoperative ACDF by the senior spinal neurosurgeon at the University of Alabama at Birmingham were enrolled in a prospective, nonrandomized study during the period from May 2010 until July 2014. Sixty-seven patients undergoing revision ACDF were enrolled using a 2-team approach with neurosurgery and otolaryngology. Dysphagia was assessed both preoperatively and postoperatively using the MD Anderson Dysphagia Inventory (MDADI) and fiberoptic endoscopic evaluation of swallowing (FEES), whereas VCP was assessed using direct visualization with VLS.RESULTSFive patients (7.5%) developed a new postoperative temporary VCP after reoperative ACDF. All of these cases resolved by 2 months postoperatively. There were no new instances of permanent VCP. Twenty-five patients had a new swallowing disturbance detected on FEES compared with their baseline assessment, with most being mild and requiring no intervention. Nearly 60% of patients showed a decrease in their postoperative MDADI scores, particularly within the physical subset.CONCLUSIONSA 2-team approach to reoperative ACDF was safe and effective, with no new cases of VCP on postoperative VLS. Dysphagia rates as assessed through the MDADI scale and FEES were consistent with other published reports.
Preoperative skin antisepsis with chlorhexidine gluconate versus povidone-iodine: a prospective analysis of 6959 consecutive spinal surgery patients
Authors: Ghobrial George M. , Wang Michael Y. , Green Barth A. , Levene Howard B. , Manzano Glen , Vanni Steven , Starke Robert M. , Jimsheleishvili George , Crandall Kenneth M. , Dididze Marina , Levi Allan D. 
Published: November 2017

OBJECTIVEThe aim of this study was to determine the efficacy of 2 common preoperative surgical skin antiseptic agents, ChloraPrep and Betadine, in the reduction of postoperative surgical site infection (SSI) in spinal surgery procedures.METHODSTwo preoperative surgical skin antiseptic agents—ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol) and Betadine (7.5% povidone-iodine solution)—were prospectively compared across 2 consecutive time periods for all consecutive adult neurosurgical spine patients. The primary end point was the incidence of SSI.RESULTSA total of 6959 consecutive spinal surgery patients were identified from July 1, 2011, through August 31, 2015, with 4495 (64.6%) and 2464 (35.4%) patients treated at facilities 1 and 2, respectively. Sixty-nine (0.992%) SSIs were observed. There was no significant difference in the incidence of infection between patients prepared with Betadine (33 [1.036%] of 3185) and those prepared with ChloraPrep (36 [0.954%] of 3774; p = 0.728). Neither was there a significant difference in the incidence of infection in the patients treated at facility 1 (52 [1.157%] of 4495) versus facility 2 (17 [0.690%] of 2464; p = 0.06). Among the patients with SSI, the most common indication was degenerative disease (48 [69.6%] of 69). Fifty-one (74%) patients with SSI had undergone instrumented fusions in the index operation, and 38 (55%) patients with SSI had undergone revision surgeries. The incidence of SSI for minimally invasive and open surgery was 0.226% (2 of 885 cases) and 1.103% (67 of 6074 cases), respectively.CONCLUSIONSThe choice of either ChloraPrep or Betadine for preoperative skin antisepsis in spinal surgery had no significant impact on the incidence of postoperative SSI.