bluuebunny/crossref_metadata_2025_split huggingface dataset:
Matrix organizations and cross-functional teams in the public sector: a systematic review
Authors: Pakarinen Mikko , Virtanen Petri Juhani 
Published: March 2017

PurposeThe purpose of this paper is to review the empirical research on matrix organizations and cross-functional teams (CFTs) in the public sector, focussing on typical application areas and settings and on motivation for deployment and evidence of utility.Design/methodology/approachThis is a systematic literature review compiled from several electronic databases. Data cover the period from 1990 to 2015 and are confined to academic articles written in English.FindingsApplications of the matrix approach in public sector organizations are found in human resource management and performance management, service development and public procurement, and creation of new organizations or organization reform and network organizations. While the proven utility of matrix organization is often unclear, especially CFTs are linked to better organizational performance, improved coordination, internal collaboration and development of cross-boundary tasks.Research limitations/implicationsMethodological limitations relate to excluded data due to non-accessible articles.Practical implicationsThe findings have practical implications for public sector organizations in adapting to a changing environment.Originality/valueThis is the first systematic literature review of matrix management in public sector organizations.
Morris B. Holbrook: an historical autoethnographic subjective personal introspection
Authors: Holbrook Morris B. 
Published: March 2017

PurposeThis paper describes the personal history and intellectual development of Morris B. Holbrook (MBH), a participant in the field of marketing academics in general and consumer research in particular.Design/methodology/approachThe paper pursues an approach characterized by historical autoethnographic subjective personal introspection or HASPI.FindingsThe paper reports the personal history of MBH and – via HASPI – interprets various aspects of key participants and major themes that emerged over the course of his career.Research limitations/implicationsThe main implication is that every scholar in the field of marketing pursues a different light, follows a unique path, plays by idiosyncratic rules, and deserves individual attention, consideration, and respect … like a cat that carries its own leash.Originality/valueIn the case of MBH, like (say) a jazz musician, whatever value he might have depends on his originality.
Philip Kotler: some of my adventures in marketing
Authors: Kotler Philip 
Published: March 2017

Purpose
This paper presents an autobiographical sketch of Philip Kotler.

Design/methodology/approach
I use an autobiographical narrative.

Findings
This sketch focuses on my contributions to the marketing discipline in teaching and, especially, in book publishing while including some of the many scholars who have collaborated with me.

Originality/value
This paper is a condensed sketch based on the full-length autobiography titled My Adventures in Marketing forthcoming on Kindle.
Enhancing the simultaneous utilization of measure in product design for academic-practitioner collaboration
Authors: Suh Taewon , Ford John , Ryu Young S. , Kim John H.S. 
Published: March 2017

PurposeThis study aims to enhance the simultaneous utilization of measure in product design by mapping out the possible and potential uses of a measure for both academicians and practitioners.Design/methodology/approachTo map out a way for the simultaneous utilization of measure, the authors assessed and portrayed the diverse facets of a four-factor measure for the development of mobile devices by adopting pluralistic techniques through a series of studies and three different study samples.FindingsThis study provided a solution for enhancing the usability of measure in product management, showing that a measure can be developed using a pluralistic methodology so that the results can be incorporated into the practitioners’ design activities that occur and when the gap between theory and practice is a knowledge production problem.Research limitations/implicationsThe main positioning of this study involves the science-design interface (Simon, 1992) to bridge the important gap between theory and practice by showcasing a measure development for product design as a strategy of intellectual arbitrage (Van De Ven and Johnson, 2006). Relying on the design scientific approach, the authors focused this study on a prescriptive procedure rather than a more rigorous methodological procedure.Practical implicationsThe authors provided product managers with a systematic and synergistic approach to developing a measure and recommended several usages of the developed measure to enhance its simultaneous utilization between academics and practitioners.Originality/valueEmphasizing pluralistic methodology in the measure development, the authors recommended the concept of intra-examination. The first-order intra-examination, utilizing Bayesian Networks, makes available the thick descriptions of the measure and supports reasoning under uncertainty. The second-order intra-examination examined nomological networks regarding the pragmatic relationships between the four factors that comprise the measure and other important constructs.
Perception of past portfolio returns, optimism and financial decisions
Authors: Khan Mohammad Tariqul Islam , Tan Siow-Hooi , Chong Lee-Lee 
Published: March 2017

PurposeThe purpose of this paper is to examine the relationships among perception of past portfolio returns, optimism and financial decisions.Design/methodology/approachThe relationships are examined using a data set of both retail and institutional investors in Malaysia and estimated using ordinary least square regression.FindingsThe results demonstrate that perception of past portfolio returns influences both retail and institutional investors’ trading and risk taking. Optimism measured as relative investment optimism and personal investment optimism similarly influences both groups of investors’ financial decisions. However, perception of past portfolio returns causes only retail investors to exhibit optimism. The results furthermore show that only for retail investors perception of past portfolio returns indirectly influences financial decisions, through the mediating channel of optimism.Practical implicationsThe findings on the influences of perception of past portfolio returns and the mediating channel in decision process help to understand the differences between retail and institutional investors. Retail investors are found to be more susceptible to optimism. Therefore, regulators in Malaysia may enhance their initiatives by incorporating the peril of forming optimistic expectations in financial decisions, by giving special focus on retail investors.Originality/valueThis paper focuses on investors’ perception of past portfolio returns and its influence on various financial decisions, unlike past portfolio returns or market returns. Also, this paper is among the first to demonstrate the mediating channel of optimism in investors’ decision process.
Accountability in Public Service Quasi‐markets: The Case of the Australian National Disability Insurance Scheme
Authors: Malbon Eleanor , Carey Gemma , Dickinson Helen 
Published: March 2017

AbstractAustralia's National Disability Insurance Scheme (NDIS) represents the latest in a worldwide shift towards individualised funding models for the delivery of care services. However, market‐based models for care deliveries bring new considerations and dilemmas for accountability. Drawing on previous work by Dickinson et al. (2014), we examine a range of accountability dilemmas developing within the early implementation of the NDIS. These relate to accountability for the following: care outcomes, the spending of public money, care workers, and advocacy and market function. Examining these accountability dilemmas reveals differences in underpinning assumptions within the design and on‐going implementation of the NDIS, suggesting a plurality of logics within the scheme, which are in tension with one another. The contribution of this paper is to set out the accountability dilemmas, analyse them according to their underpinning logics, and present the NDIS as having potential to be a hybrid institution (Skelcher and Smith 2015). How these dilemmas will be settled is crucial to the implementation and ultimate operation of the scheme.
Supporting and Assessing Agents
Authors: LAUX VOLKER 
Published: March 2017

ABSTRACTThis manuscript proposes a theory of why and when organizations “support” their employees with resources, time, and freedom beyond what seems economically optimal. The idea is that support plays an information‐generating role in that it renders output more informative about employees' abilities. This effect reduces the need to gather additional information about ability via costly monitoring and commits the firm to make replacement/promotion decisions that are more sensitive to performance. Consequently, support indirectly strengthens employees' career concern incentives and reduces the pressure on costly bonus payments. I apply the model to tech companies, academia, and capital budgeting.
Cultivated Ancient Wheats (Triticum spp.): A Potential Source of Health‐Beneficial Food Products
Authors: Arzani Ahmad , Ashraf Muhammad 
Published: March 2017

AbstractA sustainable and wholesome food supply is the most important incentive that has led to an increasing interest in ancient wheats over the past few decades. Domestication of wheat, followed by breeding efforts, largely over the past 2 centuries, has resulted in yield increases but with grain quality deterioration due to the reduction of protein, vitamins, and minerals in grains. It has also resulted in a decrease in food diversity due to the loss of genetic variation in the cultivated wheat gene pool. Ancient hulled wheats, einkorn, emmer, and spelt are among the early cereals that were domesticated in their places of origin in the Fertile Crescent of the Middle East where their wild predecessors still grow. The ancient wheats had a long history as part of human diet, and played an important role as a major source of food for the early civilizations in that region. The risks of genetic erosion of crop plants and the associated likely consequences for agriculture now call for revitalization of the unrealized potentials of ancestral species like einkorn, emmer, and spelt wheat, the domesticated ancestors of modern durum and bread wheats. These ancestors need to be exploited to maximize the sustainable supply of grain protein, fiber, minerals, and phytochemicals. In addition, ancient wheat biodiversity can be utilized to ensure sustainable wheat production in the context of climate change and low‐input organic farming systems. This review provides a holistic synthesis of the information on ancient wheats to facilitate a greater exploitation of their potential benefits.
Intra‐prelimbic cortical inhibition of striatal‐enriched tyrosine phosphatase suppresses cocaine seeking in rats
Authors: Siemsen Ben M. , Lombroso Paul J. , McGinty Jacqueline F. 
Published: March 2017

AbstractCocaine self‐administration in rats results in dysfunctional neuroadaptations in the prelimbic (PrL) cortex during early abstinence. Central to these adaptations is decreased phospho‐extracellular signal‐regulated kinase (p‐ERK), which plays a key role in cocaine seeking. Normalizing ERK phosphorylation in the PrL cortex immediately after cocaine self‐administration decreases subsequent cocaine seeking. The disturbance in ERK phosphorylation is accompanied by decreased phosphorylation of striatal‐enriched protein tyrosine phosphatase (STEP), indicating increased STEP activity. STEP is a well‐recognized ERK phosphatase but whether STEP activation during early abstinence mediates the decrease in p‐ERK and is involved in relapse is unknown. Here, we show that a single intra‐PrL cortical microinfusion of the selective STEP inhibitor, TC‐2153, immediately after self‐administration suppressed post‐abstinence context‐induced relapse under extinction conditions and cue‐induced reinstatement, but not cocaine prime‐induced drug seeking or sucrose seeking. Moreover, an intra‐PrL cortical TC‐2153 microinfusion immediately after self‐administration prevented the cocaine‐induced decrease in p‐ERK within the PrL cortex during early abstinence. Interestingly, a systemic TC‐2153 injection at the same timepoint failed to suppress post‐abstinence context‐induced relapse or cue‐induced reinstatement, but did suppress cocaine prime‐induced reinstatement. These data indicate that the STEP‐induced ERK dephosphorylation in the PrL cortex during early abstinence is a critical neuroadaptation that promotes relapse to cocaine seeking and that systemic versus intra‐PrL cortical inhibition of STEP during early abstinence differentially suppresses cocaine seeking.
Effects of group size and starvation on survival of the Asian subterranean termite Coptotermes gestroi (Isoptera: Rhinotermitidae)
Authors: Haifig Ives , Lima Juliana Toledo , Janei Vanelize , Costa‐Leonardo Ana Maria 
Published: March 2017

AbstractCoptotermes gestroi forages on wooden structures and causes substantial damage in urban areas of Brazil. The survival of foragers may be influenced by either group size or caste composition. It was hypothesised that workers survive at higher rates in larger groups and consequently exhibit higher rates of food consumption and that soldiers represent a nutritional resource for foragers during starvation periods. To test the first hypothesis, groups of 100, 200 and 400 workers were placed in experimental arenas containing wood as food. After 28 days, the units were evaluated and the number of living termites and wood consumption were estimated and compared. An analysis of the data found that there were no significant differences within the group sizes on termite survival but that relative wood consumption was significantly higher in the smaller groups. To test the second hypothesis, groups containing workers and soldiers (9:1 ratio) or only workers were placed in experimental arenas with food present or absent. Survival for each caste was monitored at 3 day intervals over 9 days to estimate the cannibalism rate. Cannibalism was significantly higher in the starved groups, but the presence of soldiers did not influence the rate of cannibalism. Colony fragmentation and starvation are stressful conditions that lead foragers of C. gestroi to adaptive behaviours in order to enhance their survival.
Toxicity profile differences of adjuvant docetaxel/cyclophosphamide (TC) between Asian and Caucasian breast cancer patients
Authors: Chow L.W.C. , Biganzoli L. , Leo A. D. , Kuroi K. , Han H. S. , Patel J. , Huang C.S. , Lu Y.S. , Zhu L. , Chow C.Y.C. , Loo W.T.Y. , Glück S. , Toi M. 
Published: March 2017

AbstractAimFor early‐stage breast cancer, four cycles of docetaxel and cyclophosphamide (TC) was proven superior to doxorubicin plus cyclophosphamide in the US Oncology 9375 trial. Given primary prophylactic antibiotics, 5% febrile neutropenia was recorded in a population comprising 75.5% Caucasians. Smaller trials and retrospective studies reviewing TC use in Asian patients did not produce similar incidence rates. This study aims to discover the variable hematological toxicities with TC use in Caucasian and Asian patients.MethodsBreast cancer data was retrospectively reviewed for patients receiving adjuvant docetaxel 60–75 mg/m2 plus cyclophosphamide 600 mg/m2 from six countries (China, Hong Kong, Japan, Taiwan, Italy, and United States). Similar number of patients with relatively balanced baseline characteristics were chosen for analysis of hematological and nonhematological toxicities and survival data.ResultsFrom March 2004 to July 2013, data of 227 patients (127 Asians and 100 Caucasian) patients were analyzed for treatment‐related toxicities. During the four cycles of TC, Asians had a significantly higher rate of grade ≥2 neutropenia than Caucasians (45.7% vs 6.0%; P <0.001) and significantly more grade ≥3 neutropenia events were documented (respectively 30.7% vs 4.0%, P <0.001). The prophylactic use of G‐CSF was similar; 26.0% in Asians and 28.0% in Caucasian (P = 0.764). There were no differences in nonhematological toxicities. No significant difference in disease‐free survival was observed between Asians and Caucasians (log‐rank P = 0.910).ConclusionsEthnic differences in toxicity profile exist between Asian and Caucasian patients given adjuvant TC. Over 30% Asians but less than 5% Caucasians experienced grade ≥3 neutropenia.
Computerized data‐driven interpretation of the intrapartum cardiotocogram: a cohort study
Authors: Georgieva Antoniya , Redman Christopher W.G. , Papageorghiou Aris T. 
Published: March 2017

AbstractIntroductionContinuous intrapartum fetal monitoring remains a significant clinical challenge. We propose using cohorts of routinely collected data. We aim to combine non‐classical (data‐driven) and classical cardiotocography features with clinical features into a system (OxSys), which generates automated alarms for the fetus at risk of intrapartum hypoxia. We hypothesize that OxSys can outperform clinical diagnosis of “fetal distress”, when optimized and tested over large retrospective data sets.Material and methodsWe studied a cohort of 22 790 women in labor (≥36 weeks of gestation). Paired umbilical blood analyses were available. Perinatal outcomes were defined by objective criteria (normal; severe, moderate or mild compromise). We used the data retrospectively to develop a prototype of OxSys, by relating its alarms to perinatal outcome, and comparing its performance against standards achieved by bedside diagnosis.ResultsOxSys1.5 triggers an alarm if the initial trace is nonreactive or the decelerative capacity (a nonclassical cardiotocography feature), exceeds a threshold, adjusted for preeclampsia and thick meconium. There were 187 newborns with severe, 613 with moderate and 3197 with mild compromise; and 18 793 with normal outcome. OxSys1.5 increased the sensitivity for compromise detection: 43.3% vs. 38.0% for severe (p = 0.3) and 36.1% vs. 31.0% for moderate (p = 0.06); and reduced the false‐positive rate (14.4% vs. 16.3%, p < 0.001).ConclusionsLarge historic cohorts can be used to develop and optimize computerized cardiotocography monitoring, combining clinical and cardiotocography risk factors. Our simple prototype has demonstrated the principle of using such data to trigger alarms, and compares well with clinical judgment.
Weighted Pseudolikelihood for SNP Set Analysis with Multiple Secondary Outcomes in Case-Control Genetic Association Studies
Authors: Sofer Tamar , Schifano Elizabeth D. , Christiani David C. , Lin Xihong 
Published: March 2017

SummaryWe propose a weighted pseudolikelihood method for analyzing the association of a SNP set, example, SNPs in a gene or a genetic pathway or network, with multiple secondary phenotypes in case-control genetic association studies. To boost analysis power, we assume that the SNP-specific effects are shared across all secondary phenotypes using a scaled mean model. We estimate regression parameters using Inverse Probability Weighted (IPW) estimating equations obtained from the weighted pseudolikelihood, which accounts for case-control sampling to prevent potential ascertainment bias. To test the effect of a SNP set, we propose a weighted variance component pseudo-score test. We also propose a penalized IPW pseudolikelihood method for selecting a subset of SNPs that are associated with the multiple secondary phenotypes. We show that the proposed variable selection procedure has the oracle properties and is robust to misspecification of the correlation structure among secondary phenotypes. We select the tuning parameter using a weighted Bayesian Information-like Criterion (wBIC). We evaluate the finite sample performance of the proposed methods via simulations, and illustrate the methods by the analysis of the multiple secondary smoking behavior outcomes in a lung cancer case-control genetic association study.
The role of preschool teacher–child interactions in academic adjustment: An intervention study with Playing‐2‐gether
Authors: Van Craeyevelt Sanne , Verschueren Karine , Vancraeyveldt Caroline , Wouters Sofie , Colpin Hilde 
Published: March 2017

BackgroundSocial relationships can serve as important risk or protective factors for child development in general, and academic adjustment in particular.AimsThis study investigated the role of teacher–child interactions in academic adjustment among preschool boys at risk of externalizing behaviour, using a randomized controlled trial study with Playing‐2‐gether (P2G), a 12‐week indicated two‐component intervention aimed at improving the affective quality of the teacher–child relationship and teacher behaviour management.SampleIn a sample of 175 preschool boys showing signs of externalizing behaviour (Mage = 4 years, 9 months, SDage = 7 months) and their teachers, we investigated P2G effects on academic engagement as well as on language achievement.MethodsAcademic engagement was rated by teachers at three occasions within one school year (T1 = pretest, T3 = post‐test, and T2 = in‐between intervention components). Language achievement was assessed by researchers at pre‐ and post‐test, using a standardized test.ResultsCross‐lagged path analyses revealed a direct intervention effect of P2G on academic engagement at Time 2. In addition, a significant indirect intervention effect was found on academic engagement at Time 3 through academic engagement at Time 2. Finally, academic engagement at Time 2 was found to predict language achievement at post‐test. A marginally significant indirect intervention effect was found on language achievement at Time 3, through academic engagement at Time 2.ConclusionsThis intervention study suggests that teacher–child interactions predict academic engagement over time, which in turn improves language achievement among preschool boys at risk of externalizing behaviour.
Safety and efficacy of 2‐weekly cabazitaxel in metastatic castration‐resistant prostate cancer
Authors: Clément‐Zhao Alice , Auvray Marie , Aboudagga Hail , Blanc‐Durand Félix , Angelergues Antoine , Vano Yann Alexandre , Mercier Florence , El Awadly Nader , Verret Benjamin , Thibault Constance , Oudard Stéphane 
Published: March 2017

ObjectivesTo evaluate the safety and efficacy of a 2‐weekly cabazitaxel schedule in patients with metastatic castration‐resistant prostate cancer (mCRPC).Materials and methodsDuring the period October 2013 to February 2016, 43 patients with mCRPC were treated with cabazitaxel (16 mg/m2, on days 1 and 15 of a 4‐week cycle) together with prophylactic granulocyte colony‐stimulating factor (G‐CSF). The safety profile and efficacy (prostate‐specific antigen [PSA] response; biological, clinical or radiological progression‐free survival [PFS] and overall survival [OS]) of the treatment were analysed.ResultsAll patients had received prior docetaxel and 79.1% abiraterone acetate. At inclusion, 46.5% were aged >70 years and 27.9% had an Eastern Cooperative Oncology Group performance status ≥2. Six patients stopped treatment because of toxicity. Grade ≥3 toxicities were: asthenia (16.3%); neutropenia (11.6%); thrombocytopenia (9.3%); diarrhoea (7%), anaemia (4.7%), febrile neutropenia (4.7%) and haematuria (2.3%). In all, 52.4% achieved a ≥30% PSA response and 40.5% had a ≥50% PSA response. The median OS was 15.2 months.ConclusionThis prospective pilot study suggests that cabazitaxel 16 mg/m² given 2‐weekly has a manageable toxicity profile in docetaxel‐ and abiraterone acetate‐pretreated patients with mCRPC. A prospective phase III trial comparing this regimen with the standard cabazitaxel regimen is planned to confirm these results.