bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sea ice, extremophiles and life on extra-terrestrial ocean worlds
Authors: Martin Andrew , McMinn Andrew 
Published: February 2017

AbstractThe primary aim of this review is to highlight that sea-ice microbes would be capable of occupying ice-associated biological niches on Europa and Enceladus. These moons are compelling targets for astrobiological exploration because of the inferred presence of subsurface oceans that have persisted over geological timescales. Although potentially hostile to life in general, Europa and Enceladus may still harbour biologically permissive domains associated with the ice, ocean and seafloor environments. However, validating sources of free energy is challenging, as is qualifying possible metabolic processes or ecosystem dynamics. Here, the capacity for biological adaptation exhibited by microorganisms that inhabit sea ice is reviewed. These ecosystems are among the most relevant Earth-based analogues for considering life on ocean worlds because microorganisms must adapt to multiple physicochemical extremes. In future, these organisms will likely play a significant role in defining the constraints on habitability beyond Earth and developing a mechanistic framework that contrasts the limits of Earth's biosphere with extra-terrestrial environments of interest.
Functional evaluation of treatment of chronic disease: Validity and reliability of the Turkish version of the Spiritual Well-Being Scale
Authors: Aktürk Ümmühan , Erci Behice , Araz Murat 
Published: February 2017

ABSTRACTObjective:This study was conducted for the purpose of adapting the Functional Assessment of Chronic Illness Therapy–Spiritual Well-Being Scale (FACIT–Sp) for the Turkish context and determining its validity and reliability.Method:In 2016, a convenience sample of 137 cancer patients from Malatya State Hospital completed a structured questionnaire, which provided demographic characteristics, and the FACIT–Sp–12 for patients with cancer. The obtained data were assessed using Cronbach's alpha reliability coefficient (α), Pearson's product-moment correlation coefficient (r), factor analysis, Bartlett's test of sphericity, and the Kaiser–Meyer–Olkin (KMO) measure of sampling adequacy.Results:The result of the KMO test was determined to be 0.827 and that of Bartlett's test 988.692, and both were observed to be significant at a level of p < 0.001. The value of Cronbach's α for the Spiritual Well-Being Scale (SWBS) was determined to be 0.87, and the α values for the SWBS subgroups ranged from 0.78 to 0.93. Our analysis determined that the factors had initial eigenvalues above 1, and that they accounted for 61.61% of the total variance.Significance of results:Our study determined that the Turkish version of the FACIT–Sp has validity and reliability and can be used in Turkish society. We believe that the scale can be used safely in determining convenient care and in planning individual educational programs to enhance patients' spiritual well-being.
Precautions against the effects of attacks in urban areas
Authors: Jensen Eric Talbot 
Published: February 2017

AbstractThe conduct of hostilities in urban areas is inherently difficult, particularly with respect to the protection of civilians. International humanitarian law places restraints on both attackers and defenders. While much is written about the obligations of attackers with respect to protecting civilians, much less attention has been paid to the defender's obligations. These obligations are routinely referred to as “passive precautions” or “precautions against the effects of attacks” and are codified in Article 58 of Additional Protocol I to the 1949 Geneva Conventions. Article 58 requires parties, “to the maximum extent feasible”, to remove civilians and civilian objects from the vicinity of military objectives, to avoid locating military objectives within or near densely populated areas, and to take other necessary precautions to protect civilians and civilian objects from the dangers resulting from military operations.Even though they are limited by only requiring those actions which are feasible, the obligations placed on the defender are far from trivial and, if applied in good faith, would certainly provide much needed protections to civilians in armed conflict, particularly in times of urban conflict. However, this ever-increasing urbanization is creating significant pressure on the doctrine of precautions in defence, stretching the “feasibility” standard beyond its capacity to adequately protect civilians. On the other hand, the emergence of advanced technology provides a mechanism for defenders to more easily and more fully comply with their obligations to segregate or protect the civilian population.For the customary obligation of “precautions against the effects of attacks” to maintain its effectiveness, particularly in urban areas of conflict, the understanding of feasibility and what is “practicable” in current urbanized armed conflicts will have to expand, increasing the practical responsibilities on the defender, including through the use of modern technology. Moreover, imposing criminal responsibility when appropriate and feasible precautions are not taken will rectify the perceived imbalance between the responsibilities of the attacker and those of the defender.
Temperament and Behavioral Problems of Preschool Children with Headache - A Controlled Study
Authors: Correia Luciana Leonetti , Linhares Maria Beatriz Martins 
Published: February 2017

AbstractThe purpose of this study was to compare differences in temperament and emotional and behavioral problems in a community sample of young children who experience headaches to those without such complaints. The whole sample was comprised 75 non-referred, preschool-aged children (3–5 years old), including 22 with headache complaints and 53 without headaches (control group). The children’s headache symptoms were assessed with a questionnaire that was given to the mothers. Rothbart’s Children’s Behavior Questionnaire was used to assess temperament, and the Child Behavior Checklist 1 ½–5 was used to assess emotional and behavioral problems. Compared with the control group, children with headache complaints showed more discomfort, which is the amount of negative affect induced by the sensory qualities of stimulation, including intensity, rate, or complexity of light, movement, sound, texture, or a combination of these modes of stimuli. These children also had higher scores for externalizing and internalizing emotional and behavioral problems compared to children without headaches. These findings show that the preschool-aged children with headaches presented more emotional and behavioral problems than the control group.
Expressed and Perceived Criticism, Family Warmth, and Symptoms in Schizophrenia
Authors: Medina-Pradas Cristina , Navarro J. Blas , Pousa Esther , Montero M. Isabel , Obiols Jordi E. 
Published: February 2017

AbstractCriticism directed by caregivers towards a family member with schizophrenia, both from the perspective of the patient and of the caregiver, predicts relapse, although both perspectives differ. This study aims to verify if the same applies to a Mediterranean sample, where criticism is not the main attitude of high expressed emotion families. The Camberwell Family Interview was applied to assess the family’s perspective, and the Perceived Criticism and the Family Emotional Involvement and Criticism Scales were used to assess the patients’ perspective, in 21 dyads. The association between both perspectives and psychotic symptoms was also examined. Results replicated those of previous studies in other countries, revealing that the perspectives on Criticism of patients and families do not match. The fact that family members also presented positive attitudes towards the patient did not cushion the patient’s perceived criticism. Thus, it seems that families considered to be critical may not be perceived as such by the patients. Furthermore, only the warmth from the family’s perspective correlated with the symptoms: positive affect proved to be more relevant than negative affect. Therefore, the patients’ subjective assessments and family warmth should be included in clinical and research proposals.
Differences in Psychosocial Risk Variables for HIV as a Function of Sexual Experience
Authors: Ramiro María Teresa , Sillero Lidia Jiménez , Bermúdez María Paz 
Published: February 2017

AbstractThe aim of this study was to analyze the differences in psychosocial risk variables for HIV as a function of sexual experience in an adolescent population. The study sample consisted of 846 adolescents of both sexes aged between 14 and 19 years. Participants responded to several questionnaires that assessed four psychosocial variables related to risk sexual behavior for HIV infection: 1) perception of peer group norms, 2) condom use self-efficacy, 3) attitudes towards condom use and 4) parental communication about sexuality, STIs, HIV and pregnancy. Participants in both groups with sexual experience (with and without penetration) reported better communication with their mothers on sexuality and scored higher in positive attitudes towards condom use than those in the group without sexual experience. The sexual experience with penetration group perceived more negative peer group norms related to safe sexual behavior than the group without sexual experience; the group without sexual experience had a higher perception of condom use self-efficacy than the sexual experience with penetration group.
Perceived Self-efficacy during an Emergency Situation Reduces Posttraumatic Stress Symptoms
Authors: Saccinto Elisa , Vallès Lola , Hilterman Ed , Roiha Malin , Pietrantoni Luca , Pérez-Testor Carles 
Published: February 2017

AbstractThis study investigates if perceived self-efficacy during an emergency situation has a protective role in the development of posttraumatic stress symptoms among Italian and Spanish survivors of several emergency situations. We explored the impact of self-efficacy in a multiple regression model including other predictors of posttraumatic stress symptoms, such as emergency prevention knowledge; trust in emergency services; risk perception of becoming a victim of an emergency situation; and conscious and active behaviors in comparison with no conscious and no active behavior during the emergency. We carried out a retrospective study recruiting 214 participants who reported their experience as victims of one specific emergency event. Results showed that survivors who perceived themselves as more self-efficacious during the traumatic event had less posttraumatic stress symptoms. In contrast, female gender, more self-threat perception and higher trauma severity were associated with more symptoms. Findings contribute to better understand human behavior in emergency situations and evidence the protective role of perceived self-efficacy beliefs among survivors of emergency situations.
Verification of Ingroup Identity as a Longitudinal Mediator between Intergroup Contact and Outgroup Evaluation
Authors: Gómez Angel , Eller Anja , Vázquez Alexandra 
Published: February 2017

AbstractAlmost six decades of research have consistently demonstrated that intergroup contact is one of the most powerful ways of improving intergroup attitudes. At least two important limitations, however, still compel researchers to continue work in this area: the issue of long-term effects of contact, and the processes underlying such effects. This report makes a theoretical and empirical contribution with regard to these two aspects introducing a new mediator of the effects of contact: verification of qualities of typical ingroup members that may or may not characterize individual group members (e.g. verification of ingroup identities). One hundred and forty-two high school students participated in a two-wave longitudinal study with 12 weeks’ lag in Spain. Cross-sectional and longitudinal mediational analyses using multiple imputation data showed that intergroup contact improves general outgroup evaluation through increasing verification of ingroup identities. This research demonstrates the relevance of considering verification of ingroup identity as a mediator for the positive effects of intergroup contact.
Using Learning Potential to Evaluate Children with Specific Language Impairment
Authors: Robles-Bello Mª Auxiliadora , Calero García Mª Dolores 
Published: February 2017

AbstractThis article presents research on a learning potential assessment that was administered to 32 preschool children with typical development, and 32 with specific language impairment receiving treatment at CADIT: the Children’s Center for Early Intervention and Development. The study’s main objective was to examine whether the language-impaired group’s cognitive profile could improve by applying learning potential methodology. Its second aim was to demonstrate the effectiveness of mediation in both groups. The results revealed significant differences between the two groups at pretest on most subscales. As for the second objective, we observed differences between pretest and posttest scores in both groups. In the second group, all differences were significant except in the case of classification and auditory memory, while in the first group, the differences between pretest and posttest scores were significant on all sub-scales but visual memory.
Interprofessional enhanced skills training in periodontology: a qualitative study of one London pilot
Authors: Radcliffe Eloise , Ghotane Swapnil G , Harrison Victoria , Gallagher Jennifer E 
Published: February 2017

Abstract
OBJECTIVES/AIMS:
Health Education England (HEE) London developed an innovative 2-year pilot educational and training initiative for enhancing skills in periodontology for dentists and dental hygienists/therapists in 2011. This study explores the perceptions and experiences of those involved in initiating, designing, delivering and participating in this interprofessional approach to training.

MATERIALS AND METHODS:
Semi-structured qualitative interviews were conducted with a purposive sample of key stakeholders including course participants (dentists and dental hygienists and/or therapists), education and training commissioners, and providers towards the end of the 2-year programme. Interviews, based on a topic guide informed by health services and policy literature, were audio-recorded and transcribed verbatim. Data were analysed based on framework methodology, using QSR NVivo 9 software to manage the data.

RESULTS:
Twenty-two people were interviewed. Although certain challenges were identified in designing, and teaching, a course bringing together different professional backgrounds and level of skills, the experiences of all key stakeholders were overwhelmingly positive relating to the concept. There was evidence of ‘creative interprofessional learning’, which led to ‘enhancing team working’, ‘enabling role recognition’ and ‘equipping participants for delivery of new models of care’. Recommendations emerged with regard to future training and wider health policy, and systems that will enable participants on future enhanced skills courses in periodontology to apply these skills in clinical practice.

CONCLUSION:
The interprofessional approach to enhanced skills training in periodontology represents an important creative innovation to build capacity within the oral health workforce. This qualitative study has provided a useful insight into the benefits and tensions of an interprofessional model of training from the perspectives of different groups of key stakeholders and suggests its application to other areas of dentistry.
Quantum lock-in force sensing using optical clock Doppler velocimetry
Authors: Shaniv Ravid , Ozeri Roee 
Published: February 2017

AbstractForce sensors are at the heart of different technologies such as atomic force microscopy or inertial sensing. These sensors often rely on the measurement of the displacement amplitude of mechanical oscillators under applied force. The best sensitivity is typically achieved when the force is alternating at the mechanical resonance frequency of the oscillator, thus increasing its response by the mechanical quality factor. The measurement of low-frequency forces, that are below resonance, is a more difficult task as the resulting oscillation amplitudes are significantly lower. Here we use a single-trapped 88Sr+ ion as a force sensor. The ion is electrically driven at a frequency much lower than the trap resonance frequency. We measure small amplitude of motion by measuring the periodic Doppler shift of an atomic optical clock transition, enhanced using the quantum lock-in technique. We report frequency force detection sensitivity as low as 2.8 × 10−20 NHz−1/2.
Control of finite critical behaviour in a small-scale social system
Authors: Daniels Bryan C. , Krakauer David C. , Flack Jessica C. 
Published: February 2017

AbstractMany adaptive systems sit near a tipping or critical point. For systems near a critical point small changes to component behaviour can induce large-scale changes in aggregate structure and function. Criticality can be adaptive when the environment is changing, but entails reduced robustness through sensitivity. This tradeoff can be resolved when criticality can be tuned. We address the control of finite measures of criticality using data on fight sizes from an animal society model system (Macaca nemestrina, n=48). We find that a heterogeneous, socially organized system, like homogeneous, spatial systems (flocks and schools), sits near a critical point; the contributions individuals make to collective phenomena can be quantified; there is heterogeneity in these contributions; and distance from the critical point (DFC) can be controlled through biologically plausible mechanisms exploiting heterogeneity. We propose two alternative hypotheses for why a system decreases the distance from the critical point.
P113 is a merozoite surface protein that binds the N terminus of Plasmodium falciparum RH5
Authors: Galaway Francis , Drought Laura G. , Fala Maria , Cross Nadia , Kemp Alison C. , Rayner Julian C. , Wright Gavin J. 
Published: February 2017

AbstractInvasion of erythrocytes by Plasmodium falciparum merozoites is necessary for malaria pathogenesis and is therefore a primary target for vaccine development. RH5 is a leading subunit vaccine candidate because anti-RH5 antibodies inhibit parasite growth and the interaction with its erythrocyte receptor basigin is essential for invasion. RH5 is secreted, complexes with other parasite proteins including CyRPA and RIPR, and contains a conserved N-terminal region (RH5Nt) of unknown function that is cleaved from the native protein. Here, we identify P113 as a merozoite surface protein that directly interacts with RH5Nt. Using recombinant proteins and a sensitive protein interaction assay, we establish the binding interdependencies of all the other known RH5 complex components and conclude that the RH5Nt-P113 interaction provides a releasable mechanism for anchoring RH5 to the merozoite surface. We exploit these findings to design a chemically synthesized peptide corresponding to RH5Nt, which could contribute to a cost-effective malaria vaccine.
Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling
Authors: Barca-Mayo Olga , Pons-Espinal Meritxell , Follert Philipp , Armirotti Andrea , Berdondini Luca , De Pietri Tonelli Davide 
Published: February 2017

AbstractCircadian rhythms are controlled by a network of clock neurons in the central pacemaker, the suprachiasmatic nucleus (SCN). Core clock genes, such as Bmal1, are expressed in SCN neurons and in other brain cells, such as astrocytes. However, the role of astrocytic clock genes in controlling rhythmic behaviour is unknown. Here we show that ablation of Bmal1 in GLAST-positive astrocytes alters circadian locomotor behaviour and cognition in mice. Specifically, deletion of astrocytic Bmal1 has an impact on the neuronal clock through GABA signalling. Importantly, pharmacological modulation of GABAA-receptor signalling completely rescues the behavioural phenotypes. Our results reveal a crucial role of astrocytic Bmal1 for the coordination of neuronal clocks and propose a new cellular target, astrocytes, for neuropharmacology of transient or chronic perturbation of circadian rhythms, where alteration of astrocytic clock genes might contribute to the impairment of the neurobehavioural outputs such as cognition.
Observation of solid–solid transitions in 3D crystals of colloidal superballs
Authors: Meijer Janne-Mieke , Pal Antara , Ouhajji Samia , Lekkerkerker Henk N. W. , Philipse Albert P. , Petukhov Andrei V. 
Published: February 2017

AbstractSelf-organization in anisotropic colloidal suspensions leads to a fascinating range of crystal and liquid crystal phases induced by shape alone. Simulations predict the phase behaviour of a plethora of shapes while experimental realization often lags behind. Here, we present the experimental phase behaviour of superball particles with a shape in between that of a sphere and a cube. In particular, we observe the formation of a plastic crystal phase with translational order and orientational disorder, and the subsequent transformation into rhombohedral crystals. Moreover, we uncover that the phase behaviour is richer than predicted, as we find two distinct rhombohedral crystals with different stacking variants, namely hollow-site and bridge-site stacking. In addition, for slightly softer interactions we observe a solid–solid transition between the two. Our investigation brings us one step closer to ultimately controlling the experimental self-assembly of superballs into functional materials, such as photonic crystals.
Ancient hybridization fuels rapid cichlid fish adaptive radiations
Authors: Meier Joana I. , Marques David A. , Mwaiko Salome , Wagner Catherine E. , Excoffier Laurent , Seehausen Ole 
Published: February 2017

AbstractUnderstanding why some evolutionary lineages generate exceptionally high species diversity is an important goal in evolutionary biology. Haplochromine cichlid fishes of Africa’s Lake Victoria region encompass >700 diverse species that all evolved in the last 150,000 years. How this ‘Lake Victoria Region Superflock’ could evolve on such rapid timescales is an enduring question. Here, we demonstrate that hybridization between two divergent lineages facilitated this process by providing genetic variation that subsequently became recombined and sorted into many new species. Notably, the hybridization event generated exceptional allelic variation at an opsin gene known to be involved in adaptation and speciation. More generally, differentiation between new species is accentuated around variants that were fixed differences between the parental lineages, and that now appear in many new combinations in the radiation species. We conclude that hybridization between divergent lineages, when coincident with ecological opportunity, may facilitate rapid and extensive adaptive radiation.