bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current health status and medical therapy of patients with pediatric-onset inflammatory bowel disease: a survey-based analysis on 1280 patients aged 10–25 years focusing on differences by age of onset
Authors: Timmer Antje , Stark Renee , Peplies Jenny , Classen Martin , Laass Martin W. , Koletzko Sibylle 
Published: September 2017

Objective
There are inconsistent reports on age-related differences in inflammatory bowel disease (IBD). On the basis of patient information, we describe the clinical presentation and therapy in relation to age at diagnosis in longstanding pediatric IBD.

Patients and methods
Two surveys were conducted in children and young adults (age: 10–25 years) by pretested postal questionnaires. The main analyses are descriptive, showing proportions and distributions per grouped age of diagnosis. Exploratory logistic regression was used to identify sociodemographic and disease-related factors associated with prognosis. Recent disease course, use of biological therapy, and resecting surgery were chosen as indicators of disease severity. Patients with a diagnosis in infancy (<2 years of age) are presented as a case series.

Results
Information of 1280 cases was available [804 Crohn’s disease (CD), 382 ulcerative colitis (UC), 94 IBD not specified] (response: 44.6 and 49.6%). Stable remission during the preceding year was reported by 675 (56.7%) patients; 825 (60.9%) patients reported feeling currenty well. Anti-tumor necrosis factor therapy was reported by 33% of CD patients and 9.3% of UC patients, immunomodulation in 82.1 and 63.2%, and corticosteroids by 78.4 and 76.1%, respectively (ever use). Age at diagnosis was not associated with indicators of severe disease. Diagnosis in infancy was reported by 37 patients.

Conclusion
Our data do not support age at diagnosis-related differences in prognosis in pediatric-onset IBD.
Percutaneous endoscopic gastrostomy under conscious sedation in patients with amyotrophic lateral sclerosis is safe: an observational study
Authors: Strijbos Denise , Hofstede José , Keszthelyi Daniel , Masclee Ad A.M. , Gilissen Lennard P.L. 
Published: September 2017

Objectives
Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease that causes muscle weakness with respiratory and swallowing dysfunction, eventually leading to death. Permanent enteral feeding is indicated in almost all patients. A percutaneous endoscopic gastrostomy (PEG) tube is considered the first choice, usually performed under conscious sedation (intravenous midazolam). Guidelines are very cautious with respect to sedation in ALS because of the risk for respiratory complications. In our tertiary referral hospital, conscious sedation has been used for many years.
Our aim was to review 30-day complications in PEG performed under conscious sedation in ALS patients (without noninvasive positive pressure ventilation during the procedure).

Patients and methods
A retrospective review, including all ALS patients undergoing PEG under conscious sedation from October 2009 to April 2016, was performed.

Results
Analysis included 45 (44% men) patients receiving intravenous midazolam sedation (mean dose 5 mg) during PEG placement, age 36–91 years (mean: 68.7 years). Forced vital capacity (FVC) was 24–116% (mean 68%), of which mild to moderate dysfunction (FVC 50–69%) was present in 42.2% of patients and (very) severe dysfunction (FVC <50%) in 8.8%. No respiratory complications (e.g. aspiration pneumonia) were observed. Other complications, for example, infection, bleeding and peritonitis occurred in, respectively, 8.9, 2.2 and 0%. Mean survival after PEG placement was 13.4 months (range: 1–45 months).

Conclusion
Conscious sedation during PEG insertion in ALS patients did not lead to respiratory complications or to an increase in other complications. Our data indicate that conscious sedation can be used safely in ALS patients with mild to moderate pulmonary dysfunction.
Does Differentiated Squamous Intraepithelial Neoplasia Occur in the Cervix?
Authors: Mai Kien T. 
Published: September 2017

Background:
Invasive cervical cell squamous carcinoma (ICC) classically develops from high grade cervical intraepithelial neoplasia of usual type (uCIN). Differentiated cervical intraepithelial neoplasia (dCIN) analogue to differentiated vulvar intraepithelial neoplasia has not been described in the cervix.

Methods:
A pilot case of ICC developing from dCIN with atypia limited to the basal/parabasal layers, focally associated with neoplastic spread above the parabasal layer (usual-like CIN pattern or u-like CIN) was identified. The previous cervical biopsy was under-diagnosed as low grade CIN. A total of 33 consecutive cases of ICC were reviewed to identify dCIN, u-like CIN and uCIN.

Results:
The ICC developed from dCIN/u-like CIN in 2 patients, 46 and 47-year-old (group 1), mixed dCIN/u-like CIN and uCIN in 7 patients, 36±3-year-old (group 2) and from uCIN in 24 patients, 47±9-year-old (group 3). In group 1, focal uCIN but not connected to ICC was also seen and Pap smears showed only hyper-keratinized cells with mildly atypical nuclei. Endocervical gland involvement by CIN was absent in group 1, focal in group 2 and extensive in group 3. All cases showed diffuse p16 staining. P53 reactivity was noted in basal/parabasal in dCIN, predominantly lower and upper parts of the epithelium in groups 2 and 3, respectively.

Conclusions:
Totally, 27% of ICC cases had associated dCIN/u-like CIN and in younger patients than in the uCIN group. Larger studies are needed to confirm dCIN/u-like CIN as significant precursor lesions of ICC.
Characteristics of Medical Adverse Events/Near Misses Associated With Laparoscopic/Thoracoscopic Surgery: A Retrospective Study Based on the Japanese National Database of Medical Adverse Events
Authors: Abe Takashige , Murai Sachiyo , Nasuhara Yasuyuki , Shinohara Nobuo 
Published: September 2017

Objectives
The aim of this study was to clarify the characteristics of adverse events/near misses during laparoscopic/thoracoscopic surgery.

Methods
Using relevant key words for minimally invasive surgeries, 540 records were identified in the database of the Japan Council for Quality Health Care. After data review and the classification of adverse events, 746 events associated with laparoscopic (laparo group) and/or thoracoscopic (thoraco group) surgery were identified. We calculated the frequency of each event, compared the frequency regarding recurrent events, and evaluated the types of event that had resulted in deaths between the 2 groups.

Results
There were 582 events in the laparo group, 159 in the thoraco group, and 5 in those undergoing combined surgery. Overall, injury of other organs (11.4%, 85/746), retention of a foreign body (9.1%, 68/746), breakage/failure of medical equipment or devices (6.2%, 46/746), massive bleeding (5.9%, 44/746), misperception of anatomy (5.6%, 42/746), and vascular injury (4.8%, 36/746) were frequently reported. There were marked differences in the frequency of injury of other organs (laparo group: 13.4%, 78/582; thoraco group: 4.4%, 7/159), massive bleeding (laparo group: 3.4%, 20/582; thoraco group: 14.5%, 23/159), and vascular injury (laparo group: 2.6%, 15/582; thoraco group: 12.6%, 20/159) between the 2 groups. Among the 56 patient-death reports, 132 adverse events were identified. In the thoraco group, bleeding events were frequently observed, whereas in the laparo group, various categories of events were noted.

Conclusions
We observed recurrent incidents and differences in the frequency between the 2 groups. Surgeons should keep in mind these characteristics. Retention of a foreign body and the breakage/malfunctioning of instruments might be reduced by the introduction of specialized checklists.
Preparation of core–shell structured CaCO
3
microspheres as rapid and recyclable adsorbent for anionic dyes
Authors: Zhao Mengen , Chen Zhenhua , Lv Xinyan , Zhou Kang , Zhang Jie , Tian Xiaohan , Ren Xiuli , Mei Xifan 
Published: September 2017

Core–shell structured CaCO
3
microspheres (MSs) were prepared by a facile, one-pot method at room temperature. The adsorbent dosage and adsorption time of the obtained CaCO
3
MSs were investigated. The results suggest that these CaCO
3
MSs can rapidly and efficiently remove 99–100% of anionic dyes within the first 2 min. The obtained CaCO
3
MSs have a high Brunauer–Emmett–Teller surface area (211.77 m
2
g
−1
). In addition, the maximum adsorption capacity of the obtained CaCO
3
MSs towards Congo red was 99.6 mg g
−1
. We also found that the core–shell structured CaCO
3
MSs have a high recycling capability for removing dyes from water. Our results demonstrate that the prepared core–shell structured CaCO
3
MSs can be used as an ideal, rapid, efficient and recyclable adsorbent to remove dyes from aqueous solution.
Parsimonious identification of evolutionary shifts for quantitative characters
Authors: Chabrol Olivier , Didier Gilles 
Published: September 2017

AbstractDetecting shifts in the rate or the trend of a character evolution is an important question which has been widely addressed. To our knowledge, all the approaches developed so far for detecting such shifts from a quantitative character strongly involved stochastic models of evolution.We propose here a novel method based on an asymmetric version of the linear parsimony (aka Wagner parsimony) for identifying the most parsimonious split of a tree into two parts between which the evolution of the character is allowed to differ. To this end, we evaluate the cost of splitting a phylogenetic tree at a given node as the integral, over all pairs of asymmetry parameters, of the most parsimonious cost which can be achieved by using the first parameter on the subtree pending from this node and the second parameter elsewhere. By testing all the nodes, we then get the most parsimonious split of a tree with regard to the character values at its tips.A study of the partial costs of the tree enabled us to develop a polynomial algorithm for determining the most parsimonious splits and their evolutionary costs. Applying this algorithm on two toy examples shows that using more than one asymmetry parameter does not always lower parsimonious costs. By using the approach on biological datasets, we obtained splits consistent with those identified by previous stochastic approaches.
The influence of a number of points on results of measurements of a turbine blade
Authors: Magdziak Marek 
Published: September 2017

Purpose
The purpose of this paper was to determine the influence of a number of measured points on results of measurements of turbine blades, which are the parts of aircraft engines. The selection of a number of points is the part of a measurement strategy in the coordinate measuring technique and determines the accuracy of measurements.

Design/methodology/approach
Numerical and experimental investigations were conducted. The measurements were simulated using different numbers of measured points. The simulated measurements were performed for the selected dispersion of measured points. The dispersion reflected the inaccuracy of a manufacturing process of the considered product and the uncertainty of measurements of curvilinear surfaces. To verify the accuracy of the numerical studies, experimental research was conducted. The real measurements were conducted using the selected coordinate measuring machine.

Findings
The gained results following the simulations can be very useful when selecting the appropriate number of measured points. The chosen number of points may be used during real measurements of turbine blades conducted on coordinate measuring machines. The results of numerical research indicate that there should be used the average radii of leading and trailing edges to increase the accuracy of measurements. The results of real coordinate measurements confirmed the results of simulation studies.

Originality/value
The main novelty of the paper is the presented methodology for determining the influence of measured points on results of measurements. The presented methodology helps the user of a coordinate measuring system select the appropriate measurement strategy of free-form surfaces applied in the aerospace industry.
Design practice in the translation traditional and glass cockpit based on General Aviation I-31T aircraft
Authors: Dudziak Jacek , Guła Paweł 
Published: September 2017

Purpose
The aim of this paper is to present the results preparation of a new glass cockpit for a general aviation category airplane with a TP100 turboprop 180 kW engine. All the works were carried out within the framework of the European programme: “Efficient Systems and Propulsion for Small Aircraft” – ESPOSA.

Design/methodology/approach
As a part of the ongoing work, the avionics equipment available on the market were thoroughly analysed. Optimization of choice was defined at the level of costs, ergonomics and development requirements of the engine manufacturer. The paper presents the issues of the realized project and discusses its specific characteristics, such as advantages and disadvantages in comparison to the conventional analogue cockpit and the possibility of adaptation for the plane.

Findings
New avionics, ground and in-flight tests were carried out. The data were collected, which, together with an ergonomics assessment done by the pilot and the observer, confirmed the previously established technical and operational objectives.

Practical implications
Most airplanes, when being modernized, encounter minor or major problems. A new approach to upgrading the avionics, involving the exchange of a piston engine with a turbine engine, which is supported by 3D software, has allowed a significant reduction of working time and costs.

Originality/value
The achieved results allow specifying a plan of changes, necessary to adapt the aircraft to a new avionic system. However, an important value is to show a new development direction of the turbine engine implementation in general aviation aircrafts.
Stray-field loss and flux distribution inside magnetic steel plate under harmonic excitation
Authors: Zhao Xiaojun , Meng Fanhui , Cheng Zhiguang , Liu Lanrong , Zhang Junjie , Fan Chao 
Published: September 2017

Purpose
This paper aims to investigate an efficient approach to model the electromagnetic behaviors and predict stray-field loss inside the magnetic steel plate under 3D harmonic magnetization conditions so as to effectively prevent the structural components from local overheating and insulation damage in electromagnetic devices.

Design/methodology/approach
An experimental setup is applied to measure all the magnetic properties of magnetic steel plate under harmonic excitations with different frequencies and phase angles. The measurement and numerical simulation are carried out based on the updated TEAM Problem 21 Model B+ (P210-B+), under the 3D harmonic magnetization conditions. An improved method to evaluate the stray-field loss is proposed, and harmonic flux distribution in the structural components is analyzed.

Findings
The influence of the harmonic order and phase angle on the stray-field loss in magnetic steel components are noteworthy. Based on the engineering-oriented benchmark models, the variations of stray-field losses and magnetic field distribution inside the magnetic components under harmonic magnetization conditions are presented and analyzed in detail.

Research limitations/implications
The capacity of the multi-function harmonic source, used in this work, was not large enough, which limits the magnetization level. Up to now, further improvements to increase the harmonic source capacity and investigations of the electromagnetic behaviors of magnetic steel components under multi-harmonic and DC-AC hybrid excitations are in progress.

Originality/value
To accurately predict the stray-field loss in magnetic steel plate, the improved method based on the combination of magnetic measurement and numerical simulation is proposed. The effects of the frequency and phase angle on the stray-field loss are analyzed.
Model order reduction for quasi-magnetostatic problems
Authors: Xie Yuqing , Li Lin , Wang Shuaibing 
Published: September 2017

Purpose
To reduce the computational scale for quasi-magnetostatic problems, model order reduction is a good option. Reduced-order modelling techniques based on proper orthogonal decomposition (POD) and centroidal Voronoi tessellation (CVT) have been used to solve many engineering problems. The purpose of this paper is to investigate the computational principle, accuracy and efficiency of the POD-based and the CVT-based reduced-order method when dealing with quasi-magnetostatic problems.

Design/methodology/approach
The paper investigates computational features of the reduced-order method based on POD and CVT methods for quasi-magnetostatic problems. Firstly the construction method for the POD and the CVT reduced-order basis is introduced. Then, a reduced model is constructed using high-fidelity finite element solutions and a Galerkin projection. Finally, the transient quasi-magnetostatic problem of the TEAM 21a model is studied with the proposed reduced-order method.

Findings
For the TEAM 21a model, the numerical results show that both POD-based and CVT-based reduced-order approaches can greatly reduce the computational time compared with the full-order finite element method. And the results obtained from both reduced-order models are in good agreement with the results obtained from the full-order model, while the computational accuracy of the POD-based reduced-order model is a little higher than the CVT-based reduced-order model.

Originality/value
The CVT method is introduced to construct the reduced-order model for a quasi-magnetostatic problem. The computational accuracy and efficiency of the presented approaches are compared.
Wideband modeling and transient analysis of sub-module in modular multilevel converter
Authors: Qi Lei , Shen Zhiyuan , Gao Jianjian , Zhao Guoliang , Cui Xiang , Kang Wei 
Published: September 2017

Purpose
This paper aims to establish the wideband model of a sub-module in a modular multilevel converter (MMC) and analyze the switch transients of the sub-module.

Design/methodology/approach
The paper builds an MMC sub-module test circuit and conducts dynamic tests both with and without the bypass thyristor. Then, it builds the wideband model of the MMC sub-module and extracts the model parameters. Finally, based on the wideband model, it simulates the switch transients and analyzes the oscillation mechanism.

Findings
The dynamic testing shows the bypass thyristor will add oscillations during switch transients, especially during the turn-on process. The thyristor acts like a small capacitor and reduces the total capacitor in the turn-on circuit loop, thus causing under-damped oscillations.

Originality/value
This paper found that the bypass thyristor will influence the MMC sub-module switch transients under certain circumstances. This paper proposes a partial inductance extraction procedure for the MMC sub-module and builds a wideband model of the sub-module. The wideband model is used to analyze and explain the switch transients, and can be further used for insulated gate bipolar transistor switch oscillation inhibition and sub-module design optimization.
30 years of IJPSM publications: an analysis
Authors: van Thiel Sandra , Bouwman Robin 
Published: September 2017

Purpose
By using the analysis of 30 years of publications in the journal International Journal of Public Sector Management, the purpose of this paper is to discover trends in publications, such as single vs joint authorship, topics and country of origin in authorship and readership.

Design/methodology/approach
Using secondary sources, such as Scopus and the Manuscript Central system, quantitative data are collected and then analysed with simple descriptive statistics.

Findings
Single authorship has gone down, while the number of articles has gone up. The authors still mainly come from English-speaking countries, as do the readers who cite the articles. The majority of publications still reports findings from qualitative, empirical research but on an increasing number of varying topics.

Originality/value
The findings give insight into the publication patterns in public management, indicating developments in the academic practices of the discipline.
Social skills scores
Authors: Dekker Karien , Kamerling Margje 
Published: September 2017

PurposeThe paper aims to examine to what extent and why parental involvement as well as characteristics of ethnic school population influence social skills scores (social position, behavioural skills) of students.Design/methodology/approachThe study used the COOL5-18 database (2010) that included 553 Dutch primary schools and nearly 38,000 students in Grades two, five and eight (aged approximately 5, 8, 11, respectively). Multilevel regression analyses were used for analysis.FindingsThe findings indicate that parental involvement has a positive impact on the social skills scores of the students; behavioural skill scores are higher in ethnically homogeneous schools and lower in schools with a high share of non-Western ethnic minority students. There is no impact of characteristics of school population composition on social position scores.Research limitations/implicationsA possible disadvantage is the way in which social skills and parental involvement were measured. These measurements are possibly negatively influenced by the teacher’s judgement of the language skills of the parents.Originality/valueExisting research focuses on the impact of parental involvement and the composition of ethnic school population on cognitive skills. This study shows that parental involvement has a positive impact on social skills. This study also shows that in schools with a homogeneous ethnic composition or a high share of native Dutch children, behavioural skills scores are higher, but social position scores are not impacted.
Lean manufacturing implementation, context and behaviors of multi-level leadership
Authors: Tortorella Guilherme , Fettermann Diego , Anzanello Michel , Sawhney Rapinder 
Published: September 2017

Purpose
The purpose of this paper is to empirically examine the relationship between the behavioral orientation of leaders from different hierarchical levels and the implementation phase of the lean manufacturing (LM) roadmap. In addition, it also aims at analyzing the influence of inherent contextual variables related to leadership.

Design/methodology/approach
The proposed method relies on both qualitative and quantitative approaches, since it combines and numerically assesses the results of semi-structured interviews with lean experts, in addition to evaluating a cross-sectional survey with 225 leaders from different Brazilian companies that are undergoing LM implementation.

Findings
The findings support the existence of a transient leadership style along the LM implementation, which is evidenced in terms of task and relation orientation and may vary according to the hierarchical level. Furthermore, the context does matter with regard to leadership style orientation along the LM roadmap phases, although not all variables matter to the same extent.

Originality/value
LM implementation is about changing both technical and socio-cultural aspects, which can be seen as the essence of leadership. The relevant question that arises is whether leaders’ behaviors from different hierarchical levels should be adapted according to the maturity of LM implementation and the contextual variables that surround leadership.