bluuebunny/crossref_metadata_2025_split huggingface dataset:
WISP3 mutational analysis in Indian patients diagnosed with progressive pseudorheumatoid dysplasia and report of a novel mutation at p.Y198*
Authors: Madhuri V. , Santhanam M. , Rajagopal K. , Sugumar L. K. , Balaji V. 
Published: July 2016

Objectives To determine the pattern of mutations of the WISP3 gene in clinically identified progressive pseudorheumatoid dysplasia (PPD) in an Indian population. Patients and Methods A total of 15 patients with clinical features of PPD were enrolled in this study. Genomic DNA was isolated and polymerase chain reaction performed to amplify the WISP3 gene. Screening for mutations was done by conformation-sensitive gel electrophoresis, beginning with the fifth exon and subsequently proceeding to the remaining exons. Sanger sequencing was performed for both forward and reverse strands to confirm the mutations. Results In all, two of the 15 patients had compound heterozygous mutations: one a nonsense mutation c.156C>A (p.C52*) in exon 2, and the other a missense mutation c.677G>T (p.G226V) in exon 4. All others were homozygous, with three bearing a nonsense mutation c.156C>A (p.C52*) in exon 2, three a missense mutation c.233G>A (p.C78Y) in exon 2, five a missense mutation c.1010G>A (p.C337Y) in exon 5, one a nonsense mutation c.348C>A (p.Y116*) in exon 3, and one with a novel deletion mutation c.593_597delATAGA (p.Y198*) in exon 4. Conclusion We identified a novel mutation c.593_597delATAGA (p.Y198*) in the fourth exon of the WISP3 gene. We also confirmed c.1010G>A as one of the common mutations in an Indian population with progressive pseudorheumatoid dysplasia. Cite this article: V. Madhuri, M. Santhanam, K. Rajagopal, L. K. Sugumar, V. Balaji. WISP3 mutational analysis in Indian patients diagnosed with progressive pseudorheumatoid dysplasia and report of a novel mutation at p.Y198* Bone Joint Res 2016;5:301–306. DOI: 10.1302/2046-3758.57.2000520.
Toxicity of zinc oxide nanoparticles to the annelid Enchytraeus crypticus in agar-based exposure media
Authors: Hrdá Kateřina , Opršal Jakub , Knotek Petr , Pouzar Miloslav , Vlček Milan 
Published: July 2016

AbstractToxicity of zinc oxide nanoparticle (ZnO-NPs) powder and water soluble salt of Zn (ZnCl
Slow pyrolysis of pre-dried sewage sludge
Authors: Staf Marek , Buryan Petr 
Published: July 2016

AbstractThis study focuses on the use of slow pyrolysis with controlled temperature increase for the thermal decomposition of pre-dried wastewater sludge. A combination of two significantly different methods was applied to investigate the pyrolysis process. The first of the experimental approaches was based on laboratory apparatus with a vertical batch retort equipped with external electrical heating. Samples of the liquid and gaseous products of the pyrolysis were taken at defined intervals throughout the pyrolysis process and were subsequently analysed. The second method involved the application of thermal analysis to the identical sludge, completed by online analysis of the pyrolysis products generated. This second method included thermogravimetry (TG), differential thermal analysis (DTA), and differential scanning calorimetry (DSC). The results obtained by both methods demonstrate that waste water sludge can be effectively converted into pyrolysis gas and oil with good combustion properties.
Kalibrierung von Wärmestromsensoren zur Detektion von kleinen Wärmeströmen
Authors: Hohmann Michael , Schalles Marc , Fröhlich Thomas 
Published: July 2016

Zusammenfassung
Am Institut für Prozessmess- und Sensortechnik der Technischen
Universität Ilmenau wurde ein neuartiger Aufbau zur Kalibrierung von
Wärmestromsensoren (WSS) entwickelt. Dieser nutzt bekannte
Oberflächentemperaturen auf beiden Seiten eines WSS um die
Empfindlichkeit des WSS zu bestimmen. Die Oberflächentemperaturen
werden mit Hilfe einer Methode bestimmt, die aus der Kalibriertechnik
für berührende Oberflächenthermometer bekannt ist. Hierbei wird anhand
der Messwerte von in zwei Prüfkörpern verteilten Thermoelementen die
jeweilige Oberflächentemperatur der Prüfkörper extrapoliert, welche im
Idealfall der Oberflächentemperatur des zwischen den Prüfkörpern
eingebrachten WSS entspricht. Die beiden extrapolierten
Oberflächentemperaturen werden durch individuell regelbare
Heizleistungen so eingestellt, dass die Differenz zwischen den
Oberflächentemperaturen definierte Werte im Bereich
± 200 mK annimmt. Mit Hilfe dieser
bekannten Temperaturdifferenzen und den Sensorsignalen kann die
Empfindlichkeit des WSS bestimmt werden.
Herausforderungen und Trends in der Fertigungsmesstechnik – Industrie 4.0
Authors: Imkamp Dietrich , Berthold Jürgen , Heizmann Michael , Kniel Karin , Peterek Martin , Schmitt Robert , Seidler Jochen , Sommer Klaus-Dieter 
Published: July 2016

Zusammenfassung
Strategische Überlegungen und Veröffentlichungen zur Zukunft der industriellen Produktion sind heute wesentlich
durch den Begriff „Industrie 4.0“ geprägt. Daher muss sich auch der Bereich der Messtechnik für die
industrielle Produktion mit diesem Begriff auseinandersetzen, wenn über zukünftige Trends und Herausforderungen in
der Messtechnik nachgedacht wird. Dazu wurde im Jahr 2011 die Roadmap Fertigungsmesstechnik 2020 der VDI/VDE-Gesellschaft
für Mess- und Automatisierungstechnik (GMA) veröffentlicht
VDI/VDE-Gesellschaft Mess- und
Automatisierungstechnik (GMA) Herausgeber: Fertigungsmesstechnik 2020, Technologie-Roadmap für die Messtechnik in der
industriellen Produktion, VDI Verein Deutscher Ingenieure e. V., Düsseldorf April 2011 ISBN 978-3-00-034706-1;
Imkamp, D., Schmitt, R., Berthold, J.: Blick in die Zukunft der Fertigungsmesstechnik, in: tm – Technisches Messen,
Vol. 79, No. 10, 433–439, 2012, https://www.vdi.de/uploads/media/tm$_$Blick$_$
in$_$die$_$Zukunft$_$der$_$Fertigungsmesstechnik$_$2012.0251.pdf.
. Der
Inhalt dieser Roadmap wird hier an den neuen Entwicklungen aus dem Bereich Industrie 4.0 gespiegelt und in entsprechend
erweiterter und aktualisierter Form dargestellt.
Dynamische Charakterisierung eines Dreikomponenten Kraftsensors mit Hilfe eines Lorentzkraft-Lastwechslers
Authors: Schleichert Jan , Carlstedt Matthias , Marangoni Rafael R. , Rahneberg Ilko , Fröhlich Thomas 
Published: July 2016

Zusammenfassung
Kraftsensoren basierend auf Dehnungsmesstreifen werden häufig in statischen oder
quasistatische Messaufgaben verwendet. Hierfür sind statisch kalibrierte Aufnehmer gut
geeignet. Bei dynamischen Messungen treten ab der ersten Resonanzfrequenz des mechanischen
Systems eine starke Messabweichungen auf. Dieser Artikel beschreibt daher die dynamische
Charakterisierung eines Mehrkomponenten Kraftsensors, welcher für Messungen in der
Lorentzkraft-Wirbelstromprüfung, einem neuartigen Verfahren der zerstörungsfreien
Werkstoffprüfung, eingesetzt wird. Dieses Verfahren basiert auf einer dynamischen
Kraftmessung. Für die dynamische Kalibrierung wird ein System vorgestellt, welches die
Nutzung verschiedener Testsignale zur Bestimmung der Systemparameter des Kraftsensors
ermöglicht. Für verschiedene Testsignale werden Messergebnisse gezeigt und die Hauptursachen
für Messabweichungen diskutiert. Basierend auf einer Parameterschätzung kann eine Entfaltung
der Sensorcharakteristik anhand eines inversen Filters [1]aus den
Messsignalen erfolgen.
Pengaruh Games Memorize Card Terhadap Hasil Belajar Siswa pada Operasi Hitung Bilangan
Authors: Anastasya Detta , Dewi Sri Ratna , Murnaka Nerru Pranuta 
Published: July 2016

<p>Kemampuan dasar matematika sangatlah penting untuk siswa Sekolah Dasar (SD). Salah satunya adalah kemampuan melakukan operasi hitung bilangan. Kondisi di lapangan menunjukkan bahwa hasil belajar siswa Sekolah Dasar (SD) tentang operasi hitung bilangan masih rendah. Hal ini terjadi karena aktivitas siswa di sekolah pada umumnya masih dibatasi oleh guru, sehingga membuat anak-anak menjadi cepat bosan saat pembelajaran berlangsung. Oleh karena itu, diperlukannya suatu suasana pembelajaran yang baru dengan berbantuan media sehingga dapat membuat pembelajaran menjadi menyenangkan serta membuat siswa lebih aktif. Salah satu media pembelajaran yang akan digunakan adalah <em>Games Memorize Card. </em>Tujuan penelitian ini untuk melihat perbedaan hasil belajar siswa sebelum dan sesudah penggunaan <em>Games Memorize Card</em> serta pengaruh <em>Games Memorize Card</em> terhadap hasil belajar siswa. Adapun subjek dari penelitian ini adalah siswa kelas III SD XYZ di Kabupaten Tangerang. Pengambilan sampel menggunakan teknik <em>purposive sampling</em>. Penelitian ini merupakan penelitian pra-eksperimen dengan menggunakan<em> one group pretest-posttest design</em>. Instrumen yang akan digunakan di dalam penelitian ini berupa tes. Teknik analisis data yang digunakan yaitu uji Wilcoxon dan menghitung nilai N-Gain. Dari hasil penelitian diperoleh bahwa penggunaan <em>Games Memorize Card </em>mampu meningkatkan hasil belajar siswa kelas III SD pada operasi hitung bilangan.</p><p><em>Basic math skill is very important for elementary school students. One of them is ability to do number arithmetic operations. Based on the fact show that elementary school students learning outcomes about number arithmetic operations still low. This case happen because activity at school in general still limited by teacher, so that make children become easily bored when learning be held. Therefore, need a new learning environment with assisted media so it can make learning becomes fun and make students active. One of the media that will be used is Games Memorized Card. The purpose of this research for see the difference in learning outcomes before and after use Games Memorized Card and the influence of Games Memorized Card on student learning outcomes. As for the subject of this research is 3<sup>th</sup> grade students in XYZ elementary school in Tangerang district. The sampling technique had been used purposive sampling. This research is a pre-experimental design that used the one group pretest-posttest design. The instrument to be used in this research is test. The data analysis technique to be used are Wilcoxon test and calculate the value of N-Gain. The result of research obtained that use Games Memorized Card able to increase learning outcomes 3<sup>th</sup> grade students elementary school on the number arithmetic operations.</em></p>
Uma Recessão sem fim? As Transformações da Teoria e das Políticas Econômicas na Perspectiva Latino-Americana
Authors: Puyana Alícia 
Published: July 2016

Resumo: este ensaio avalia criticamente os paradigmas da teoria econômicaneoclássica a partir da crise mundial de 2007-2008, assim como a trajetória daseconomias latino-americanas após a implementação das reformas neoliberais nasdécadas de 1970 e que provocaram um aumento acentuado da desigualdade empraticamente todos os países. A redução da desigualdade que ocorreu na décadade 2000 é atribuída, sobretudo, à ascensão de governos de centro e centro-esquerda no subcontinente. Numa perspectiva de longo prazo, evidencia-se que os indicadores Gini de desigualdade, em 2010, apenas retornaram aos valores de 1960.Palavras-chave: Teoria econômica. Crise mundial. Globalização. Desigualdade.América Latina.
McDonaldization in Households
Authors: Woolridge Jacob Paul , Stanley-Stevens Leslie 
Published: July 2016

<p>Using data collected over three years and mimicking the methodology of Arnold et al. (2012) in Los Angeles, a study in Texas was conducted in which 66 families opened their homes and allowed video, survey data, and pictorial evidence to be collected. These data are used to determine if McDonaldization has spread from the public sphere into the private sphere by determining if the four factors of McDonaldization: predictability, calculability, efficiency, and control are present, and if so, in what ways they are represented. Ultimately, every single household studied showed instances of all four factors of McDonaldization, thus heavily supporting the hypothesis that McDonaldization has encroached into the private sphere. This phenomenon will be explained by using McDonaldization either as a rational means to pursue individualistic self-actualization as described through Maslow’s Hierarchy of Needs or as a means by corporations to extend their own factor of control into the private sphere and thus influence consumers. Finally, the fifth factor of McDonaldization, irrationality emerging from rationality, was examined with examples provided. </p>
Reaching for Health Equity and Social Justice in Baltimore: The Evolution of an Academic-Community Partnership and Conceptual Framework to Address Hypertension Disparities
Authors: Cooper Lisa A. , Purnell Tanjala S. , Ibe Chidinma A. , Halbert Jennifer P. , Bone Lee R. , Carson Kathryn A. , Hickman Debra , Simmons Michelle , Vachon Ann , Robb Inez , Martin-Daniels Michelle , Dietz Katherine B. , Golden Sherita Hill , Crews Deidra C. , Hill-Briggs Felicia , Marsteller Jill A. , Boulware L. Ebony , Miller Edgar R. , Levine David M. 
Published: July 2016

<p>Cardiovascular health disparities persist despite decades of recognition and the availability of evidence-based clinical and public health interventions. Racial and ethnic minorities and adults in urban and low-income communities are highrisk groups for uncontrolled hypertension (HTN), a major contributor to cardiovascular health disparities, in part due to inequitable social structures and economic systems that negatively impact daily environments and risk behaviors. This commentary presents the Johns Hopkins Center to Eliminate Cardiovascular Health Disparities as a case study for highlighting the evolution of an academic-community partnership to overcome HTN disparities. Key elements of the iterative development process of a Community Advisory Board (CAB) are summarized, and major CAB activities and engagement with the Baltimore community are highlighted. Using a conceptual framework adapted from O’Mara-Eves and colleagues, the authors discuss how different population groups and needs, motivations, types and intensity of community participation, contextual factors, and actions have shaped the Center’s approach to stakeholder engagement in research and community outreach efforts to achieve health equity. <em>Ethn Dis. </em>2016;26(3):369-378; doi:10.18865/ ed.26.3.369 </p>
Outcome Disparities in African American Compared with European American Women with ER +HER 2- Tumors Treated within an Equal-Access Health Care System
Authors: Costantino Nicholas S. , Freeman Benjamin , Shriver Craig D. , Ellsworth Rachel E. 
Published: July 2016

<p><strong>Purpose: </strong>Breast cancer mortality rates are higher for African American women (AAW) than for any other ethnic group in the United States. Recent reports suggest that outcome disparities between AAW and European American women (EAW) are present in the ER+HER2- subtype. To improve our understanding, pathological characteristics, mortality and molecular profiles from women treated within an equal-access health care system were evaluated. <strong></strong></p><p><strong>Procedures: </strong>All AAW (n=90) and EAW (n=308) with ER+HER2- tumors were identified. Gene expression profiles were generated from primary breast tumors from 57 AAW and 181 EAW. Pathological characteristics, survival and gene expression analysis were evaluated using chi-square analysis, log-rank tests and ANOVA. </p><p><strong>Results: </strong>Tumors from AAW were significantly more likely to be PR-, Ki67+ and of higher grade. Tumor stage, size and lymph node status did not differ significantly, nor did mortality rates (P=.879). At the molecular level, genes PSPHL and CRYBB2P1 were expressed at significantly higher levels in tumor tissues as well as normal stroma and blood from AAW. Polymorphisms controlling expression of each gene were identified with minor allele frequencies differing significantly between populations but not between cases and controls within each population. <strong></strong></p><p><strong>Conclusions: </strong>Survival disparities were not detected in patients with ER+HER2- tumors treated within an equal-access health care system and molecular differences in tumors were not causal. Thus, outcome disparities in AAW with ER+HER2- tumors are largely attributable to socioeconomic factors affecting access to screening and treatment, rather than reflecting underlying biological differences. <em>Ethn Dis. </em>2016;26(3):407-416; doi:10.18865/ed.26.3.407 </p>
Levels of Participants Satisfaction with Initial Contact and Examination Visit: The Hispanic Community Health Study/ Study of Latinos (HCHS /SOL)
Authors: Talavera Ana C. , Buelna Christina , Espinoza Giacinto Rebeca A. , Castañeda Sheila F. , Giachello Aida L. , Crespo-Figueroa Madeline , Hernandez Johanne B. , Rodriguez Rosalinda , Abreu Maria de los Angeles , Sanchez Carlos M. , Perreira Krista 
Published: July 2016

<p><strong>Objective: </strong>This study examined perceived satisfaction among Hispanic/Latino individuals who participated in a baseline examination for the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a large cohort study of 16,415 adults living in four selected communities. <strong></strong></p><p><strong>Method: </strong>An estimated 22% (<em>n</em>= 3,584) of participants completed a questionnaire regarding satisfaction with staff attention, the overall experience during the study examination, and the influence of the informed consent digital video disc (DVD). <strong></strong></p><p><strong>Results: </strong>The majority of participants who completed the questionnaire expressed overall satisfaction with the study. Most participants reported that staff were friendly, courteous and respectful and study test procedures were clearly explained. Participants who preferred to complete the interview in Spanish felt that the informed consent DVD positively influenced their ability to make an informed decision to enroll in the study. Participants who preferred to complete the interview in English tended to report that the baseline examination was longer than expected compared with participants who completed the interview in Spanish. <strong></strong></p><p><strong>Conclusion: </strong>Results demonstrate that culturally and linguistically trained staff and the use of the study’s informed consent DVD were effective in explaining study procedures and positively influenced decisions to participate in the HCHS/SOL study. These results can inform recruitment and enrollment strategies for future participation of minority groups into longitudinal cohort studies. <em>Ethn Dis. </em>2016;26(3):435-442; doi:10.18865/ed.26.3.435 </p>
La Nación y Clarín: dos propuestas para la democratización y reinserción en occidente a propósito de la guerra de malvinas
Authors: Díaz César Luis , Giménez Mario Jorge 
Published: July 2016

La contribución de los diarios La Nación y Clarín con el golpe cívico militar de 1976 en la Argentina y la legitimación del terrorismo de Estado como método para aniquilar a la “subversión” y para restaurar el “orden”, particularidad a la que hemos denominado “periodismo hermesiano”, los convirtió en primer término en socios ideológicos de la dictadura. Este vínculo inicialmente virtual, encontraría su materialidad a partir de la conformación de la empresa productora de papel para diarios Papel Prensa S.A., en la cual se convertirían en socios económicos. En carácter de tales aceptaron y justificaron la supresión de los derechos políticos y sociales y las restricciones a la libertad de prensa, así como también acompañaron la posición de la dictadura argentina frente a su par chilena en el diferendo por el Beagle. La recuperación temporaria de las Islas Malvinas entre el 2 de abril y el 14 de junio de 1982, si bien fue tratada de manera dispar en términos cuantitativos por ambos (La Nación70 editoriales, Clarín 30) ambos coincidieron en jerarquizar, antes que el día a día de los acontecimientos bélicos, una serie de tópicos destinados a fortalecer identificaciones colectivas y a poner en la agenda ciertas temáticas vinculadas con el futuro institucional del país para contribuir a enderezar el rumbo político en la posguerra tanto en el orden interno, cuanto en el orden internacional.
Evaluation of Brace Treatment for Infant Hip Dislocation in a Prospective Cohort
Authors: Upasani Vidyadhar V. , Bomar James D. , Matheney Travis H. , Sankar Wudbhav N. , Mulpuri Kishore , Price Charles T. , Moseley Colin F. , Kelley Simon P. , Narayanan Unni , Clarke Nicholas M.P. , Wedge John H. , Castañeda Pablo , Kasser James R. , Foster Bruce K. , Herrera-Soto Jose A. , Cundy Peter J. , Williams Nicole , Mubarak Scott J. 
Published: July 2016

Background:
The use of a brace has been shown to be an effective treatment for hip dislocation in infants; however, previous studies of such treatment have been single-center or retrospective. The purpose of the current study was to evaluate the success rate for brace use in the treatment of infant hip dislocation in an international, multicenter, prospective cohort, and to identify the variables associated with brace failure.

Methods:
All dislocations were verified with use of ultrasound or radiography prior to the initiation of treatment, and patients were followed prospectively for a minimum of 18 months. Successful treatment was defined as the use of a brace that resulted in a clinically and radiographically reduced hip, without surgical intervention. The Mann-Whitney test, chi-square analysis, and Fisher exact test were used to identify risk factors for brace failure. A multivariate logistic regression model was used to determine the probability of brace failure according to the risk factors identified.

Results:
Brace treatment was successful in 162 (79%) of the 204 dislocated hips in this series. Six variables were found to be significant risk factors for failure: developing femoral nerve palsy during brace treatment (p = 0.001), treatment with a static brace (p < 0.001), an initially irreducible hip (p < 0.001), treatment initiated after the age of 7 weeks (p = 0.005), a right hip dislocation (p = 0.006), and a Graf-IV hip (p = 0.02). Hips with no risk factors had a 3% probability of failure, whereas hips with 4 or 5 risk factors had a 100% probability of failure.

Conclusions:
These data provide valuable information for patient families and their providers regarding the important variables that influence successful brace treatment for dislocated hips in infants.

Level of Evidence:
Prognostic Level I. See Instructions for Authors for a complete description of levels of evidence.
About the forces working on a heavenly body, and oscillatory movement of the body moving on an orbit, in solar system
Authors: Kulik Ivan Viktorovich , Kulik Viktor Ivanovich 
Published: July 2016

It is important to describe not movement of a heavenly body on an orbit, and to understand the reasons of its movement and those power potential systems and forces which operate this movement, that not always allow to make the differential equations simply. It is important to represent also graphically changes of key parameters of any heavenly body addressing around of the Center. Centrifugal and centripetal forces – the main forces of one order working on a heavenly body, addressing around of the Center. Present article also is devoted to this, and, all parameters in algebraic expressions are considered dependent not only from in regular intervals current time, but also from each other, or, for example, from «radius – vector» – positions of a heavenly body from focus of an elliptic orbit.