bluuebunny/crossref_metadata_2025_split huggingface dataset:
Loop‐Mediated Isothermal Amplification (LAMP): A Rapid and Sensitive Tool for Quality Assessment of Meat Products
Authors: Kumar Yogesh , Bansal Sangita , Jaiswal Pranita 
Published: October 2017

AbstractLoop‐mediated isothermal amplification (LAMP) is a novel method that amplifies target nucleic acids under isothermal conditions. It is a rapid, specific, and sensitive method, which does not require costly thermal cyclers for the detection of nucleic acids. Thus, it is suitable for on‐site detection assays under low‐resource settings. It can also be integrated on compact lab‐on‐a‐chip devices for the development of micro‐total analysis systems. This review discusses LAMP‐based methods, as well as LAMP‐based centrifugal, microfluidic, and other fluid‐handling devices, which have been developed for the assessment of meat quality parameters that are related to the presence or absence of nucleic acids, for example, animal species identification and microbiological quality. Advances in improving the rapidity, specificity, and sensitivity of LAMP techniques for the assessment of these meat quality parameters are also discussed in this review.
Use of Multi‐Intake Temporal Dominance of Sensations (TDS) to Evaluate the Influence of Wine on Cheese Perception
Authors: Galmarini Mara V. , Loiseau Anne‐Laure , Debreyer Doëtte , Visalli Michel , Schlich Pascal 
Published: October 2017

AbstractEven if wine and cheese have long been consumed together, there is little sensory evidence on how wine can influence the perception of cheese. In this work 4 cheeses were dynamically characterized in terms of dominant sensations without and with wine consumption in between intakes. The tasting protocol was based on multi‐intake temporal dominance of sensations (TDS) coupled with hedonic rating. Frequent wine and cheese consumers (n = 31) evaluated 4 cheeses (Epoisses, Chaource, and 2 different Comté) over 3 consecutive bites. In the following sessions they performed the same task, but taking sips of wine (rosé Riceys, white Burgundy, red Burgundy, and red Beaujolais) between bites. All cheese–wine combinations were tasted over 4 sessions. TDS data were analyzed in terms of attribute duration of dominance by ANOVA, MANOVA, and canonical variate analysis. Results showed that wine consumption had an impact (P < 0.1) on dominance duration of attributes of cheeses, particularly on salty and some aromatic notes. But, as opposed to a previous work done by the same team, wine had no impact on the preference of cheese; this stayed constant under all the evaluating conditions.Practical ApplicationThis paper aims to validate an innovative protocol on dynamic sensory data acquisition in which consumers evaluate the impact of a beverage (wine) on a solid food (cheese). This protocol is complementary to a previous one presented in this journal, where the effect of cheese was tested on wine. Together they make up an interesting approach towards developing a new tool for the food sector to better understand the impact of one food product on another. This could lead to a better description of a whole meal, something which is still missing in sensory science.
Human CD8+EMRA T cells display a senescence‐associated secretory phenotype regulated by p38 MAPK
Authors: Callender Lauren A. , Carroll Elizabeth C. , Beal Robert W. J. , Chambers Emma S. , Nourshargh Sussan , Akbar Arne N. , Henson Sian M. 
Published: October 2017

SummaryCellular senescence is accompanied by a senescence‐associated secretory phenotype (SASP). We show here that primary human senescent CD8+ T cells also display a SASP comprising chemokines, cytokines and extracellular matrix remodelling proteases that are unique to this subset and contribute to age‐associated inflammation. We found the CD8+ CD45RA+CD27− EMRA subset to be the most heterogeneous, with a population aligning with the naïve T cells and another with a closer association to the effector memory subset. However, despite the differing processes that give rise to these senescent CD8+ T cells once generated, they both adopt a unique secretory profile with no commonality to any other subset, aligning more closely with senescence than quiescence. Furthermore, we also show that the SASP observed in senescent CD8+ T cells is governed by p38 MAPK signalling.
Overwintering survival of grapevine scale Parthenolecanium persicae (Hemiptera: Coccidae) in the Canberra region of Australia
Authors: Hayes Angus , Neeman Teresa , Cooper Paul D 
Published: October 2017

AbstractScales of the genus Parthenolecanium have become pests in some grapevine growing regions of Australia but not in the wine region in and around Canberra, Australian Capital Territory, Australia. Previous work suggests that population size of scales on certain cultivars varied, with one potential reason for observed differences being the number of scales surviving winter. Parthenolecanium persicae (Fabricius, 1776) overwinters as a third‐instar nymph under the bark of grapevines. We investigated whether differences in bark thickness and thermal insulation contributed to survivorship and the extent to which the scales could tolerate cold temperatures. The thickness of bark and the temperature difference across the bark varied among cultivars studied (Shiraz, Chardonnay, Tempranillo, Riesling, Viognier), but these parameters were not correlated among cultivars. Third‐instar scales could survive −15°C in dry conditions but froze and were killed when wet and temperatures were cooled to −10°C. Neither the differences in bark thickness nor scale cold tolerance could explain differences in infestations among cultivars observed previously. Grapevine scale outbreaks in various Australian grape‐growing regions may coincide with changes in climate as a result of increased winter survival.
Tethyan changes shaped aquatic diversification
Authors: Hou Zhonge , Li Shuqiang 
Published: October 2017

ABSTRACTThe Tethys Ocean existed between the continents of Gondwana and Laurasia from the Triassic to the Pliocene. Analyses of multiple biogeographic and phylogenetic histories reveal that the subsequent breakup of the Tethys greatly influenced the distributions of many species. The ancestral Tethyan realm broke into five biogeographic provinces, including the present‐day East Pacific, West Atlantic, East Atlantic, Mediterranean Sea, and Indo‐West Pacific. Palaeogeographic maps illustrate the Mesozoic Atlantic opening, the Cenozoic closure of the Tethys, the Messinian Salinity Crisis, the mid‐Miocene closure of the Central American Seaway, and Quaternary geological changes. Further, we consider Cenozoic sea‐level changes and the formation of freshwater habitats. These reconstructions allow assessment of patterns of aquatic diversification for marine and freshwater animals, and comparison of vicariance and dispersal processes. Estimated divergence times indicate that fragmentation of the Tethys was responsible for the vicariant speciation of aquatic animals because these dates are consistent with associated tectonic events. The opening of the Atlantic Ocean during the Cretaceous is responsible for the earliest isolation between the West and East Atlantic. The mid‐Miocene closure of the Tethys, which blocked global equatorial currents, appears to have isolated the Atlantic/Mediterranean Sea and Indo‐West Pacific. Finally, formation of the Isthmus of Panama isolated East Pacific and West Atlantic marine organisms. Dispersals related to the Messinian Salinity Crisis and Quaternary sea‐level changes influenced population structuring. Tethyan changes affected marine habitats, created new freshwater habitats, inland caves and ancient lakes along the Alps and Himalayas, and influenced anchialine caves at the edge of the ancient sea. The extensive new habitats provided opportunities for colonisation and rapid diversification. Future work should focus on testing the biological impact of the series of Tethyan changes.
Dimensions of difficulty in children reported to have an autism spectrum diagnosis and features of extreme/‘pathological’ demand avoidance
Authors: O'Nions Elizabeth , Viding Essi , Floyd Caroline , Quinlan Emma , Pidgeon Connie , Gould Judith , Happé Francesca 
Published: October 2017

BackgroundA subset of individuals with autism spectrum disorder (ASD) resemble descriptions of extreme/‘pathological’ demand avoidance, displaying obsessive avoidance of everyday demands and requests, strategic or ‘socially manipulative’ behaviour and sudden changes in mood. Investigating challenging presentations using dimensional description may prove preferable to identifying subgroups. However, there remains an imperative to explore which behavioural traits appear most problematic to inform quantitative investigation. This study provides an in‐depth exploration of parent perspectives on maladaptive behaviour in children reported to have an autism spectrum diagnosis and features of extreme/‘pathological’ demand avoidance.MethodParents completed a tailored semistructured interview about their child's behaviour, focusing on difficulties relevant to descriptions of extreme/‘pathological’ demand avoidance. The 26 interviews rated as scoring above threshold for ‘substantial’ features of extreme/‘pathological’ demand avoidance on relevant indicators were analysed qualitatively using a general inductive approach.ResultsNew themes that emerged from these data included attempts by the child to control situations and others’ activities. Avoidance behaviours in this sample could be described as ‘strategic’ rather than ‘manipulative’. A range of factors, including a negative emotional response to demands, but also phobias, novelty, and uncertainty, were perceived to play a role in triggering extreme behaviour.ConclusionsThese descriptions highlight the importance of systematically measuring noncompliance, attempts to control situations and others' activities, and extreme mood variability in individuals with ASD. These dimensions represent important targets for intervention, given their considerable impact on daily life.
A Long‐Term Effect of Perceptual Individuation Training on Reducing Implicit Racial Bias in Preschool Children
Authors: Qian Miao K. , Quinn Paul C. , Heyman Gail D. , Pascalis Olivier , Fu Genyue , Lee Kang 
Published: October 2017

This study tracked the long‐term effect of perceptual individuation training on reducing 5‐year‐old Chinese children's (N = 95, Mage = 5.64 years) implicit pro‐Asian/anti‐Black racial bias. Initial training to individuate other‐race Black faces, followed by supplementary training occurring 1 week later, resulted in a long‐term reduction of pro‐Asian/anti‐Black bias (70 days). In contrast, training Chinese children to recognize White or Asian faces had no effect on pro‐Asian/anti‐Black bias. Theoretically, the finding that individuation training can have a long‐term effect on reducing implicit racial bias in preschoolers suggests that a developmentally early causal linkage between perceptual and social processing of faces is not a transitory phenomenon. Practically, the data point to an effective intervention method for reducing implicit racism in young children.
Postnatal reduction of tuberous sclerosis complex 1 expression in astrocytes and neurons causes seizures in an age‐dependent manner
Authors: Zou Jia , Zhang Bo , Gutmann David H. , Wong Michael 
Published: October 2017

SummaryObjectiveEpilepsy is one of the most prominent symptoms of tuberous sclerosis complex (TSC), a genetic disorder, and may be related to developmental defects resulting from impaired TSC1 or TSC2 gene function in astrocytes and neurons. Inactivation of the Tsc1 gene driven by a glial‐fibrillary acidic protein (GFAP) promoter during embryonic brain development leads to widespread pathologic effects on astrocytes and neurons, culminating in severe, progressive epilepsy in mice (Tsc1GFAP‐Cre mice). However, the developmental timing and cellular specificity relevant to epileptogenesis in this model has not been well defined. The present study evaluates the effect of postnatal Tsc1 gene inactivation on pathologic features of astrocytes and neurons and development of epilepsy.MethodsAn inducible Tsc1 knock‐out mouse was created utilizing a tamoxifen‐driven GFAP‐CreER line (Tsc1GFAP‐CreER mice) with TSC1 reduction induced postnatally at 2 and 6 weeks of age, and compared to conventional Tsc1GFAP‐Cre mice with prenatal TSC1 reduction. Western blotting, immunohistochemistry, histology, and video–electroencephalography (EEG) assessed mechanistic target of rapamycin (mTOR) pathway activation, astrogliosis, neuronal organization, and spontaneous seizures, respectively.ResultsTsc1 gene inactivation at 2 weeks of age was sufficient to cause astrogliosis and mild epilepsy in Tsc1GFAP‐CreER mice, but the phenotype was much less severe than that observed with prenatal Tsc1 gene inactivation in Tsc1GFAP‐Cre mice. Both astrocytes and neurons were affected by prenatal and postnatal Tsc1 gene activation to a degree similar to the severity of epilepsy, suggesting that both cellular types may contribute to epileptogenesis.SignificanceThese findings support a model in which the developmental timing of TSC1 loss dictates the severity of neuronal and glial abnormalities and resulting epilepsy.
Body composition measurement in young children using quantitative magnetic resonance: a comparison with air displacement plethysmography
Authors: Chen L.‐W. , Tint M.‐T. , Fortier M. V. , Aris I. M. , Shek L. P.‐C. , Tan K. H. , Rajadurai V. S. , Gluckman P. D. , Chong Y.‐S. , Godfrey K. M. , Kramer M. S. , Henry C. J. , Yap F. , Lee Y. S. 
Published: October 2017

SummaryBackgroundQuantitative magnetic resonance (QMR) has been increasingly used to measure human body composition, but its use and validation in children is limited.ObjectiveWe compared body composition measurement by QMR and air displacement plethysmography (ADP) in preschool children from Singapore's multi‐ethnic Asian population (n = 152; mean ± SD age: 5.0 ± 0.1 years).MethodsAgreements between QMR‐based and ADP‐based fat mass and fat mass index (FMI) were assessed using intraclass correlation coefficient (ICC), reduced major axis regression and Bland–Altman plot analyses. Analyses were stratified for the child's sex.ResultsSubstantial agreement was observed between QMR‐based and ADP‐based fat mass (ICC: 0.85) and FMI (ICC: 0.82). Reduced major axis regression analysis suggested that QMR measurements were generally lower than ADP measurements. Bland–Altman analysis similarly revealed that QMR‐based fat mass were (mean difference [95% limits of agreement]) −0.5 (−2.1 to +1.1) kg lower than ADP‐based fat mass and QMR‐based FMI were −0.4 (−1.8 to +0.9) kg/m2 lower than ADP‐based FMI. Stratification by offspring sex revealed better agreement of QMR and ADP measurements in girls than in boys.ConclusionsQMR‐based fat mass and FMI showed substantial agreement with, but was generally lower than, ADP‐based measures in young Asian children.
Transparent polycrystalline nanoceramics consisting of triclinic Al2SiO5 kyanite and Al2O3 corundum
Authors: Gaida Nico A. , Nishiyama Norimasa , Masuno Atsunobu , Schürmann Ulrich , Giehl Christopher , Beermann Oliver , Ohfuji Hiroaki , Bednarcik Jozef , Kulik Eleonora , Holzheid Astrid , Irifune Tetsuo , Kienle Lorenz 
Published: October 2017

AbstractTransparent polycrystalline nanoceramics consisting of triclinic Al2SiO5 kyanite (91.4 vol%) and Al2O3 corundum (8.6 vol%) were fabricated at 10 GPa and 1200‐1400°C. These materials were obtained by direct conversion from Al2O3‐SiO2 glasses fabricated using the aerodynamic levitation technique. The material obtained at 10 GPa and 1200°C shows the highest optical transparency with a real in‐line transmission value of 78% at a wavelength of 645 nm and a sample‐thickness of 0.8 mm. This sample shows equigranular texture with an average grain size of 34 ± 13 nm. The optical transparency increases with decreasing mean grain size of the constituent phases. The relationship between real in‐line transmission and grain size is well explained by a grain‐boundary scattering model based on a classical theory.
Sintering dense boron carbide without grain growth under high pressure
Authors: Liu Lixin , Li Xuhai , He Qiang , Xu Liang , Cao Xiuxia , Peng Xusheng , Meng Chuanmin , Wang Wenqiang , Zhu Wenjun , Wang Yuan 
Published: October 2017

AbstractTraditionally, densification and grain growth are two competing processes in sintering of ceramics. To improve the density, while limiting grain growth at the same time, an ultrahigh pressure (>1 GPa) is employed here and results in plastic deformation as the dominant densification mechanism during the sintering process. In this way, fully dense boron carbide (B4C) structural ceramics without grain growth is prepared under the pressure of 4.5 GPa at low temperature of 1300°C in 5 minutes, while showing excellent mechanical properties such as Vickers hardness of 38.04 GPa, Young's modulus of 487.7 GPa, and fracture toughness of 3.87 MPa·m1/2. This study should also facilitate the development of other structural ceramics for practical applications.
School‐Based Health Centers and Adolescent Substance Use: Moderating Effects of Race/Ethnicity and Socioeconomic Status
Authors: Bersamin Melina , Paschall Mallie J. , Fisher Deborah A. 
Published: October 2017

ABSTRACTBACKGROUNDSchool‐based health centers (SBHCs) have been associated with many positive health and academic outcomes. The current study extends previous research and examines possible differences in the association between SBHC exposure and adolescent alcohol, tobacco, and other drug use by race/ethnicity, sex, and socioeconomic status (SES).METHODSCalifornia Healthy Kids Survey data from 504 traditional high schools in California were linked with publicly available data on SBHCs and school demographics. Multilevel logistic regression analyses were conducted controlling for school and individual characteristics.RESULTSSignificant interactions suggest that SBHC exposure was inversely associated with past 30‐day alcohol use, binge drinking, and cigarette and e‐cigarette use among African American youth and negatively associated with cigarette and marijuana use among Asian youth, relative to whites. There was also a significant interaction between SBHC exposure and parent education for past 30‐day alcohol use and binge drinking. No significant sex interactions were observed.CONCLUSIONSSBHC exposure appears to be inversely related to substance use among youth in some ethnic minority groups and youth of lower SES. This may have implications regarding SBHC placement and investment. Additional research is necessary to understand the mechanisms through which SBHCs may influence adolescent substance use and other health behaviors.
Robust Improvements on Reasoning Performance Following Discussion in Japan
Authors: Boku Mariko , Yama Hiroshi , Mercier Hugo 
Published: October 2017

AbstractGroup discussion significantly improves performance on intellective problems. However, most experiments have been conducted in Western cultures. Cross‐cultural psychology suggests that members of Eastern cultures might be less likely to benefit from group discussion. One experiment in Japan suggested that this was not the case, but this experiment suffered from some limitations. To address these limitations, Japanese participants were asked to solve an intellective task four times: individually (pre‐test), in small discussion groups (test), individually again (transfer task, post‐test), and individually after a delay (delayed post‐test). The results revealed a robust improvement during group discussion. Groups in which at least one member had found the correct answer individually agreed on it during the discussion. Moreover, and in contrast with results obtained in Western cultures, most groups with no such member also found the correct answer. The gains obtained during discussion were maintained in the transfer tasks. This result provides further evidence that the improvement of reasoning performance in group discussion is a universal phenomenon, and provides support for the practice of collaborative learning in Japan.
Comparison of Four Artificial Light Technologies for Indoor Aquaponic Production of Swiss Chard, Beta vulgaris, and Kale, Brassica oleracea
Authors: Oliver Luke P. , Coyle Shawn D. , Bright Leigh A. , Shultz R. Charles , Hager Janelle V. , Tidwell James H. 
Published: October 2017

AbstractTo date, most aquaponic research has been conducted outdoors in tropical climates or in greenhouses in subtropical climates. For more northerly latitudes, aquaponic production will require supplemental light in greenhouses or insulated buildings. Two separate 3‐wk growth trials were conducted to evaluate the effects of four different lighting technologies on the growth of Swiss chard, Beta vulgaris (Trial 1) and kale, Brassica oleracea (Trial 2) in aquaponic systems. Light technologies evaluated included fluorescent (FLO), metal halide (MH), induction (IND), and light‐emitting diode (LED). Four 1175‐L systems were used with all four light types represented in each system in a complete block design. Juvenile Nile tilapia, Oreochromis niloticus (241 g) were stocked in each system and fed a floating 32% protein diet at a rate of 60 g/m2 of plant grow space per day. In Trial 1, Swiss chard plants grown under LED lights for 3 wk achieved significantly higher (P ≤ 0.05) average individual weights (117.7 g), higher production per unit of area (3535 g/m2), and higher production per unit of energy (32.3 g/m2/kwh) than Swiss chard grown under the other three light types, which did not differ significantly (P > 0.05) from each other. In Trial 2, kale grown under LED lights achieved significantly higher (P ≤ 0.05) average individual weights (102.9 g), higher production per unit of area (2136.6 g/m), and higher production per unit of energy (381.5 g/m2/kwh) than kale grown under the other three light types, which did not differ significantly (P > 0.05). The results of the two trials are in agreement and indicate that LED lights were superior to MH, FLO, and IND lights in terms of absolute plant growth as well as growth per unit of energy consumed.
Competitive devaluations in commodity‐based economies: Colombia and the Pacific Alliance Group
Authors: Caporale Guglielmo Maria , Costamagna Rodrigo , Rossini Gustavo 
Published: October 2017

AbstractThis paper investigates whether there is an S‐curve in Colombia using bilateral and disaggregated quarterly data for the period 1991 to 2014. More precisely, the short‐run effects of a depreciation on the trade balance (TB) are analyzed in 27 industries covered by the Pacific Alliance Group free trade agreement. The S‐curve found in sectors representing 30 percent of total industrial production suggests that in these cases competitive devaluations have a positive effect on the TB in the short run. Our findings have important policy implications: since only large competitive devaluations can restore TB equilibrium, industrial restructuring would appear to be a more sensible strategy, though this cannot be achieved in the short run and is instead a medium‐ to long‐term goal.
Have money and credit data releases helped markets to predict the interest rate decisions of the European Central Bank?
Authors: Jung Alexander 
Published: October 2017

AbstractThis paper examines whether money and credit data releases by the European Central Bank (ECB) have provided markets with additional clues about the future course of its monetary policy. It conducts a novel econometric approach, as suggested by El‐Shagi and Jung (Eur J Polit Econ 39:222–234, 2015), based on a combination of an Ordered Probit model explaining future policy rate changes (sample 2000–2014) and the Vuong test for model selection. Overall, our empirical results support the view that information contained in money and credit aggregates is used by markets when assessing forthcoming interest changes of the ECB.