bluuebunny/crossref_metadata_2025_split huggingface dataset:
GRATITUDE ET BIEN-ÊTRE SOCIAL : MÉCANISMES EXPLICATIFS DES EFFETS DE LA GRATITUDE SUR LE BIEN-ÊTRE INDIVIDUEL ET COLLECTIF
Authors: Shankland Rébecca , André Christophe 
Published: August 2017

La gratitude a été définie comme une émotion sociale agréable qui génère de nombreuses conséquences positives sur la santé physique, mentale et sociale par le biais d’une augmentation de la capacité à apprécier les expériences, à percevoir des bénéfices même en cas d’adversité, et à développer, maintenir et améliorer les relations sociales. Toutefois, loin d’être un état dont les effets ne bénéficieraient qu’à l’individu, la gratitude engendre également des effets bénéfiques pour autrui, notamment par le biais de son expression : l’expression de gratitude génère un sentiment d’utilité et de valeur sociale chez l’interlocuteur, augmentant par-là le bien-être psychologique. Au-delà du simple effet de contagion émotionnelle, la gratitude entraîne une amélioration réciproque des relations, ce qui favorise le maintien ou l’amélioration des relations sociales constructives, auxquelles le bien-être est étroitement lié. Les mécanismes explicatifs des liens entre gratitude et bien-être individuel et collectif sont présentés, ainsi que des perspectives de recherche et d’applications pratiques.
POUR UNE POLITIQUE DU BONHEUR INSPIRÉE DE LA PSYCHOLOGIE POSITIVE
Authors: Lecomte Jacques 
Published: August 2017

Cet article comporte deux grandes parties. D’une part, relativement au débat entre psychologues hédonistes et eudémonistes, il propose une réconciliation de ces deux perspectives en considérant que le bonheur comporte à la fois du sens et du bien-être. D’autre part, il propose une politique du bonheur, en l’exemplifiant dans trois domaines : l’enseignement, la justice et le monde du travail.
High incidence of cervical ribs indicates vulnerable condition in Late Pleistocene woolly rhinoceroses
Authors: van der Geer Alexandra A.E. , Galis Frietson 
Published: August 2017

Mammals as a rule have seven cervical vertebrae, a number that remains remarkably constant. Changes of this number are associated with major congenital abnormalities (pleiotropic effects) that are, at least in humans, strongly selected against. Recently, it was found that Late Pleistocene mammoths (Mammuthus primigenius) from the North Sea have an unusually high incidence of abnormal cervical vertebral numbers, approximately ten times higher than that of extant elephants. Abnormal numbers were due to the presence of large cervical ribs on the seventh vertebra, indicating a homeotic change from a cervical rib-less vertebra into a thoracic rib-bearing vertebra. The high incidence of cervical ribs indicates a vulnerable condition and is thought to be due to inbreeding and adverse conditions that may have impacted early pregnancies in declining populations. In this study we investigated the incidence of cervical ribs in another extinct Late Pleistocene megaherbivore from the North Sea and the Netherlands, the woolly rhinoceros (Coelodonta antiquitatis). We show that the incidence of abnormal cervical vertebral numbers in the woolly rhinoceros is unusually high for mammals (15,6%,n = 32) and much higher than in extant Rhinoceratidae (0%,n = 56). This indicates that woolly rhinoceros lived under vulnerable conditions, just like woolly mammoths. The vulnerable condition may well have contributed to their eventual extinction.
O Trabalho Sujo com a Morte, o Estigma e a Identidade no Ofício de Coveiro
Authors: Monteiro Daniel Francisco Bastos , Pereira Verônica Fujise , Oliveira Laureane Leopoldino de , Lima Oscar Palma , Carrieri Alexandre de Pádua 
Published: August 2017

<p>Este artigo tem como objetivo compreender questões acerca do ofício de coveiro e identificar quais as marcas sociais existentes na profissão, como ela é vista pelos profissionais e como estes se identificam com o seu exercício. Optou-se por desenvolver uma pesquisa de cunho qualitativo, na qual foram entrevistados 08 coveiros de 03 cemitérios de Belo Horizonte (02 públicos e 01 judaico). Para a análise dos relatos, foram utilizadas categorias da Análise Linguística do Discurso, sendo possível identificar dois percursos semânticos a respeito da profissão de coveiro. O primeiro diz respeito ao discurso que retrata as categorias estigmatizantes que permeiam a profissão e ao preconceito e discriminação que os coveiros sofrem perante a sociedade. Já o segundo percurso está atrelado ao processo de construção das identidades dos coveiros e a maneira como eles passaram a lidar com a morte após começar a trabalhar com uma atividade que está diretamente ligada a ela. Concluímos este trabalho, portanto, com reflexões acerca dos estigmas presentes na profissão de coveiro e sugestões para pesquisas futuras. </p>
Contrasting Features of Monsoon Precipitation Around the Meghalaya Plateau Under Westerly and Easterly Regimes
Authors: Fujinami Hatsuki , Sato Tomonori , Kanamori Hironari , Murata Fumie 
Published: August 2017

AbstractPrecipitation features around the Meghalaya Plateau, northeast India, during summer are investigated using a 17 year (1998–2014) high‐spatial‐resolution Tropical Rainfall Measuring Mission precipitation radar data set. Precipitation around the plateau fell into two distinct regimes based on the low‐level wind direction that fluctuates on intraseasonal time scales over Bangladesh, windward of the plateau: a westerly regime (WR) and an easterly regime (ER). Under the WR, strong low‐level onshore southwesterlies across Bangladesh encounter the plateau, and localized strong low‐level southerlies running parallel to the Arakan Mountains (i.e., the barrier jet) also blow toward the plateau, concentrating convective unstable air onto its southern slopes. The low‐level wind fields and large‐scale upper level divergent fields promote frequent and intense orographic rainfall along the southern slopes due to forced uplift, generating high precipitation. In contrast, under the ER, strong southeasterlies that blow along the Gangetic Plain without encountering the plateau and subsidence inhibit upward motion around the plateau, resulting in low precipitation. Diurnal variations in precipitation significantly affect the daily precipitation around the plateau under both regimes. High rainfall frequency persists over the southern slopes between 2100 and 1200 LT of the next day under the WR, whereas modest rainfall frequency occurs between 0000 and 0600 LT under the ER, with a daytime minimum and nocturnal maximum in both regimes. The atmospheric boundary layer processes over Bangladesh regulate the wind speed and vertical structure of the low‐level wind toward the plateau, with deceleration during daytime and acceleration at night (i.e., nocturnal jet) that result in the nocturnal rainfall maximum.
Modeling Craton Destruction by Hydration‐Induced Weakening of the Upper Mantle
Authors: Liao Jie , Wang Qin , Gerya Taras , Ballmer Maxim D. 
Published: August 2017

AbstractGrowing evidence shows that lithospheric mantle beneath cratons may contain a certain amount of water that originated from dehydration of subducted slabs or mantle metasomatism. As water can significantly reduce the viscosity of nominally anhydrous minerals such as olivine, hydration‐induced rheological weakening is a possible mechanism for the lithospheric thinning of cratons. Using 2‐D thermomechanical numerical models, we investigated the influence of water on dislocation and diffusion creep of olivine during the evolution of cratonic lithosphere. Modeling results indicate that dislocation creep of wet olivine alone is insufficient to trigger dramatic lithospheric thinning within a timescale of tens of millions of years, even with an extremely high water content. However, if diffusion creep is incorporated, significant convective instability will occur at the base of the lithosphere and drive lithospheric mantle dripping, which results in intense lithospheric thinning. We performed semianalytical models to better understand the influence of various parameters on the onset of convective instability. The convective instability promoted by hydration weakening drives lithospheric mantle dripping beneath cratons and thus provides a possible mechanism for cratonic thinning.
Hydrothermal nontronite formation associated with microbes from low‐temperature diffuse hydrothermal vents at the South Mid‐Atlantic Ridge
Authors: Ta Kaiwen , Peng Xiaotong , Chen Shun , Xu Hengchao , Li Jiwei , Du Mengran , Hao Jialong , Lin Ying 
Published: August 2017

AbstractOceanic nontronite deposits have been identified to be closely related to low‐temperature hydrothermal activities. However, their formation mechanisms associated with microbes in diffuse hydrothermal vents still remain largely unknown. The friable deposits, collected from the low‐temperature diffuse flow at the Southern Atlantic Ridge, display a layered structure. Scanning electron microscope and transmission electron microscope analyses reveal that abundant filamentous, spherical, and rod‐shaped mineralized forms are preserved in the yellowish‐green layer of the deposits. These mineralized forms primarily consist of Si and Fe. Selected area electron diffraction patterns of the mineralized forms indicate that they are composed of nontronite. High intensities of 12C and 12C14N signals derived from cellular structures determined by nanosecondary ion mass spectrometry suggest the intimate relationship between nontronite and microbes. The results of 454 pyrosequencing analyses provide insights into the microbial communities involved in the biologically induced mineralization in the yellowish‐green layer. We propose an evolutionary model for establishing paragenetic sequences among nontronite, Mn oxide, and Fe oxyhydroxide in the deposits. This paragenetic sequence could be widespread in modern and ancient low‐temperature hydrothermal fields.
Changes in intestinal microbiota and their effects on allogeneic stem cell transplantation
Authors: Shallis Rory M. , Terry Christopher M. , Lim Seah H. 
Published: August 2017

AbstractThe human intestinal microbiota is essential for microbial homeostasis, regulation of metabolism, and intestinal immune tolerance. Rapidly evolving understanding of the importance of the microbiota implicates changes in the composition and function of intestinal microbial communities in an assortment of systemic conditions. Complications following allogeneic stem cell transplant now join the ever‐expanding list of pathologic states regulated by intestinal microbiota. Dysbiosis, or disruption of the normal ecology of this microbiome, has been directly implicated in the pathogenesis of entities such as Clostridium difficile infections, graft‐versus‐host disease (GVHD), and most recently disease relapse, all of which are major causes of morbidity and mortality in patients undergoing allogeneic stem cell transplant. In this review, we elucidate the key origins of microbiotic alterations and discuss how dysbiosis influences complications following allogeneic stem cell transplant. Our emerging understanding of the importance of a balanced and diverse intestinal microbiota is prompting investigation into the appropriate treatment of dysbiosis, reliable and early detection of such, and ultimately its prevention in patients to improve the outcome following allogeneic hematopoietic stem cell transplant.
Clinical outcomes in adult patients with aplastic anemia: A single institution experience
Authors: Boddu Prajwal , Garcia‐Manero Guillermo , Ravandi Farhad , Borthakur Gautam , Jabbour Elias , DiNardo Courtney , Jain Nitin , Daver Naval , Pemmaraju Naveen , Anderlini Paolo , Parmar Simrit , KC Devendra , Akosile Mary , Pierce Sherry A. , Champlin Richard , Cortes Jorge , Kantarjian Hagop , Kadia Tapan 
Published: August 2017

AbstractNewer treatment modalities are being investigated to improve upon historical outcomes with standard immunosuppressive therapy (IST) in aplastic anemia (AA). We analyzed outcomes of adult patients with AA treated with various combinatorial anti‐thymoglobulin‐based IST regimens in frontline and relapsed/refractory (R/R) settings. Pretreatment and on‐treatment clinical characteristics were analyzed for relationships to response and outcome. Among 126 patients reviewed, 95 were treatment‐naïve (TN) and 63, R/R (including 32 from the TN cohort); median ages were 49 and 50 years, respectively. Overall survival (OS) was superior in IST responders (P < .001). Partial response to IST was associated with shorter relapse‐free survival (RFS), as compared with complete response (P = .03). By multivariate analysis, baseline platelet and lymphocyte count predicted for IST response at 3 and 6 months, respectively. While additional growth factor interventions led to faster count recovery, there were no statistically significant differences in RFS or OS across the various frontline IST regimens (i.e., with/without G‐CSF or eltrombopag). While marrow cellularity did not correlate with peripheral‐blood counts at 3 months, cytomorphological assessment revealed dyspoietic changes in all nonresponders with hypercellular‐marrow indices. Covert dysplasia, identified through early bone marrow assessment, has implications on future therapy choices after IST failure. Salvage IST response depended upon prior response to ATG: prior responders (46%) vs. primary refractory (0%) (P < .01). In the R/R setting, there was no survival difference between IST and allogeneic stem cell transplant groups, with a trend toward superior OS in the former. Transplant benefits in the R/R setting may be underrealized due to transplant‐related mortality.
A One‐Dimensional Fluidic Nanogenerator with a High Power Conversion Efficiency
Authors: Xu Yifan , Chen Peining , Zhang Jing , Xie Songlin , Wan Fang , Deng Jue , Cheng Xunliang , Hu Yajie , Liao Meng , Wang Bingjie , Sun Xuemei , Peng Huisheng 
Published: August 2017

AbstractElectricity generation from flowing water has been developed for over a century and plays a critical role in our lives. Generally, heavy and complex facilities are required for electricity generation, while using these technologies for applications that require a small size and high flexibility is difficult. Here, we developed a fluidic nanogenerator fiber from an aligned carbon nanotube sheet to generate electricity from any flowing water source in the environment as well as in the human body. The power conversion efficiency reached 23.3 %. The fluidic nanogenerator fiber was flexible and stretchable, and the high performance was well‐maintained after deformation over 1 000 000 cycles. The fiber also offered unique and promising advantages, such as the ability to be woven into fabrics for large‐scale applications.
Cross‐Coupling of α‐Carbonyl Sulfoxonium Ylides with C−H Bonds
Authors: Barday Manuel , Janot Christopher , Halcovitch Nathan R. , Muir James , Aïssa Christophe 
Published: August 2017

AbstractThe functionalization of carbon–hydrogen bonds in non‐nucleophilic substrates using α‐carbonyl sulfoxonium ylides has not been so far investigated, despite the potential safety advantages that such reagents would provide over either diazo compounds or their in situ precursors. Described herein are the cross‐coupling reactions of sulfoxonium ylides with C(sp2)−H bonds of arenes and heteroarenes in the presence of a rhodium catalyst. The reaction proceeds by a succession of C−H activation, migratory insertion of the ylide into the carbon–metal bond, and protodemetalation, the last step being turnover‐limiting. The method is applied to the synthesis of benz[c]acridines when allied to an iridium‐catalyzed dehydrative cyclization.
Enantioselective Light Harvesting with Perylenediimide Guests on Self‐Assembled Chiral Naphthalenediimide Nanofibers
Authors: Sethy Ramarani , Kumar Jatish , Métivier Rémi , Louis Marine , Nakatani Keitaro , Mecheri Nila Mohan Thazhe , Subhakumari Akhila , Thomas K. George , Kawai Tsuyoshi , Nakashima Takuya 
Published: August 2017

AbstractSelf‐assembling molecular systems often display amplified chirality compared to the monomeric state, which makes the molecular recognition more sensitive to chiral analytes. Herein, we report the almost absolute enantioselective recognition of a chiral perylenediimide (PDI) molecule by chiral supramolecular nanofibers of a bichromophoric naphthalenediimide (NDI) derivative. The chiral recognition was evaluated through the Förster resonance energy transfer (FRET) from the NDI‐based host nanofibers to the guest PDI molecules. The excitation energy was successfully transferred to the guest molecule through efficient energy migration along the host nanofiber, thus demonstrating the light‐harvesting capability of these hybrid systems. Furthermore, circularly polarized luminescence (CPL) was enantioselectively sensitized by the guest molecule as the wavelength band and sign of the CPL signal were switched in response to the chiral guest molecule.
Lysine‐Targeting Covalent Inhibitors
Authors: Pettinger Jonathan , Jones Keith , Cheeseman Matthew D. 
Published: August 2017

AbstractTargeted covalent inhibitors have gained widespread attention in drug discovery as a validated method to circumvent acquired resistance in oncology. This strategy exploits small‐molecule/protein crystal structures to design tightly binding ligands with appropriately positioned electrophilic warheads. Whilst most focus has been on targeting binding‐site cysteine residues, targeting nucleophilic lysine residues can also represent a viable approach to irreversible inhibition. However, owing to the basicity of the ϵ‐amino group in lysine, this strategy generates a number of specific challenges. Herein, we review the key principles for inhibitor design, give historical examples, and present recent developments that demonstrate the potential of lysine targeting for future drug discovery.
TPE‐conjugated biomimetic and biodegradable polymeric micelle for AIE active cell imaging and cancer therapy
Authors: Zhuang Weihua , Ma Boxuan , Liu Gongyan , Li Gaocan , Wang Yunbing 
Published: August 2017

ABSTRACTSmart nanocarrier for simultaneous drug delivery and cellular imaging is ideal for both cancer therapy and diagnosis. In this work, polymeric micelles based on the tetraphenylethene (TPE) conjugated poly(N6‐carbobenzyloxy‐l‐lysine)‐block‐poly(2‐methacryloyloxyethyl phosphorylcholine) (TPE‐PLys‐b‐PMPC) copolymer are successfully prepared. Such biomimetic and biodegradable TPE‐PLys‐b‐PMPC micelles exhibit remarkable aggregation‐induced emission (AIE) feature and great biocompatibility, showing great potential for bioimaging application. In addition, anticancer drug doxorubicin (DOX) can be incorporated into the core of micelles and the intracellular release of DOX can be furthermore traced through the fluorescent imaging of these AIE micelles. As expected, this DOX‐loading polymeric micelle shows significant growth inhibition against HeLa cells and 4T1 cells and such TPE‐PLys‐b‐PMPC micelles would be a promising drug carrier for potential cancer therapy and bioimaging. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45651.
Antimicrobial nanocomposites and electrospun coatings based on poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) and copper oxide nanoparticles for active packaging and coating applications
Authors: Castro Mayorga Jinneth Lorena , Fabra Rovira María José , Cabedo Mas Luis , Sánchez Moragas Gloria , Lagarón Cabello José María 
Published: August 2017

ABSTRACTActive biodegradable poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) (PHBV) melt mixed nanocomposites and bilayer structures containing copper oxide (CuO) nanoparticles were developed and characterized. The bilayer structures consisted of a bottom layer of compression molded PHBV3 (3% mol valerate) coated with an active electrospun fibers mat made with CuO nanoparticles and PHBV18 (18% valerate) derived from microbial mixed cultures and cheese whey. The results showed that the water vapor permeability increased with the CuO addition while the oxygen barrier properties were slightly enhanced by the addition of 0.05 wt % CuO nanoparticles to nanocomposite films but a negligible effect was registered for the bilayer structures. However, the mechanical properties were modified by the addition of CuO nanoparticles. Interestingly, by incorporating highly dispersed and distributed CuO nanoparticles in a coating by electrospinning, a lower metal oxide loading was required to exhibit significant bactericidal and virucidal performance against the food‐borne pathogens Salmonella enterica, Listeria monocytogenes, and murine norovirus. The biodisintegration tests of the samples under composting conditions showed that even the 0.05% CuO‐coated structures biodegraded within 35 days. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45673.
Synthesis of poly(acrylonitrile‐co‐divinylbenzene‐co‐vinylbenzyl chloride)‐derived hypercrosslinked polymer microspheres and a preliminary evaluation of their potential for the solid‐phase capture of pharmaceuticals
Authors: Subri Nur Nida Syamimi , Cormack Peter A. G. , Md. Jamil Siti Nurul Ain , Abdullah Luqman Chuah , Daik Rusli 
Published: August 2017

ABSTRACTPoly[acrylonitrile (AN)‐co‐divinylbenzene (DVB)‐co‐vinylbenzyl chloride (VBC)] terpolymers were synthesized by precipitation polymerization in the form of porous polymer microspheres. The poly(AN‐co‐DVB‐co‐VBC) polymers were then hypercrosslinked, via a Friedel‐Crafts reaction with FeCl3 in nitrobenzene, to provide a significant uplift in the specific surface areas of the polymers. FTIR spectra of the hypercrosslinked poly(AN‐co‐DVB‐co‐VBC)s showed that the chloromethyl groups derived from VBC were consumed by the Friedel‐Crafts reactions, which was consistent with successful hypercrosslinking. Hypercrosslinking installed a number of new, small pores into the polymers, as evidenced by a dramatic increase in the specific surface areas upon hypercrosslinking (from ∼530 to 1080 m2 g−1). The hypercrosslinked polymers are very interesting for a range of applications, not least of all for solid‐phase extraction (SPE) work, where the convenient physical form of the polymers (beaded format), their low mean particle diameters, and narrow particle size distributions, as well as their high specific surface areas and polar character (arising from the AN residues), make them attractive candidates as SPE sorbents. In this regard, in a preliminary study one of the hypercrosslinked polymers was utilized as an SPE sorbent for the capture of the polar pharmaceutical diclofenac from a polar environment. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45677.
Epoxy adhesive with high underwater adhesion and stability based on low viscosity modified Mannich bases
Authors: Zhou Jinjun , Wan Yun , Liu Na , Yin Hao , Li Bo , Sun Dewen , Ran Qianping 
Published: August 2017

ABSTRACTA series of Mannich base curing agents were synthesized by using different structured phenols and amines. The phenols were phenol, o‐cresol, and nonylphenol, and the amines were diethylenetriamine, m‐xylylenediamine, and JEFFAMINE D230 polyetheramine. The chemical structures of Mannich bases were confirmed by 1H nuclear magnetic resonance and Fourier transform infrared spectroscopy. The curing agents had low viscosities in the range of 19.9 to 1549 mPa s. The curing behavior of diglycidyl ether of bisphenol A with these curing agents was studied by differential scanning calorimetry. The mechanical properties and thermal properties of the cured epoxies were also investigated and compared. Lap‐shear adhesion in air and underwater was studied by using stainless steel substrates, and the adhesion after ageing in hot water (80 °C) was also investigated. Adhesive cured with phenol modified m‐xylylenediamine showed the highest underwater adhesion around 5.9 MPa, which was comparable to other ones tested in air. In addition, the high adhesive strength was kept after ageing in hot water for 7 days. The structural influence of the curing agents on mechanical property and adhesive performances were discussed. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45688.