bluuebunny/crossref_metadata_2025_split huggingface dataset:
Costos de la Atención de Pacientes con Equinococosis Quística Humana en un hospital de Niños en Lima-Perú, Periodo 2006-2010.
Authors: Fano Patricia , Hernández Henry , Falcón Néstor 
Published: February 2016

Objetivo: Determinar los costos de la atención de pacientes con diagnóstico de Equinococosis Quística Humana (EQH) en el Instituto Nacional de Salud del Niño, durante el periodo 2006-2010. Metodología: Se revisó las historias clínicas de 143 pacientes diagnosticados con EQH de las cuales se obtuvo información del sexo, edad, así como los costos de: consultorio externo, estancia hospitalaria, farmacia, exámenes de laboratorio, imagenología e intervenciones quirúrgicas. Las historias clínicas fueron solicitadas a la Unidad de Registros Médicos de la Oficina de Estadística e Informática y los costos fueron proporcionados por la Unidad de Cuentas Corrientes y el Servicio de Farmacia. Resultados y Conclusiones: La mayoría de pacientes atendidos estuvieron en el rango de edad de 5 a 9 años (48.2%). El promedio de estancia hospitalaria fue de 34 días, con un rango de 2 a 227 días. La ubicación pulmonar del quiste fue la de mayor ocurrencia (39.9%). El costo de todos los pacientes atendidos fue 130 743,1 dólares de Estados Unidos y el costo promedio según el tipo de paciente se dio de la siguiente manera: pacientes hospitalizados con cirugía fue de 914,3 dólares, pacientes hospitalizados sin cirugía fue de 298,7 dólaresy pacientes sin hospitalización fue de 88,1 dólares. En farmacia se reportó el mayor costo el cual corresponde al 53.7% del total. Por la importancia de esta zoonosis se requiere acción inmediata, decidida y combinada de los servicios de sanidad animal y salud pública para controlarla.
O sucesso da inculturação do telemóvel nas comunidades moçambicanas e a sua múltipla funcionalidade social
Authors: Joanguete Celestino Vaz 
Published: February 2016

A estrutura do trabalho é construída em três momentos: o primeiro discute a empregabilidade no dispositivo móvel na monitoria de governação. Nesta abordagem a reflexão tráz à superfície a questão do uso das mensagens SMS na monitoria dos processos eleitorais. O segundo momento debruça sobre o telemóvel no processo comunicativo, no qual são enfatizados os últimos progressos tecnológicos das infraestruturas de comunicação; o terceiro momento descreve o impactos da "Economia Móvel" nos processos de desenvolvimento do negócio e transações comerciais, onde se destaca o impacto social dos serviços móveis de consulta, transferências bancárias e pagamentos de serviços.
Proposta Metodológica de Avaliação de Comunicação Governamental Digital
Authors: Carniello Monica Franchi 
Published: February 2016

O acesso à informação é uma das condições para o desenvolvimento. A comunicação governamental em ambiente digital, que propicia possibilidades amplas de acesso à informação e uma potencialidade de participação é o enfoque desse artigo. O objetivo do artigo é propor parâmetros de análise para avaliação da comunicação governamental oficial em ambiente digital. A pesquisa caracteriza-se como exploratória, por propor um método a ser testado para validação. O delineamento da pesquisa é bibliográfico e qualitativo. Foram propostos parâmetros para análise de sítios oficiais das unidades da federação, organizados em cinco dimensões e trinta e três itens de análise, e parâmetros de análise para avaliação dos perfis oficiais de unidades da federação nas redes sociais digitais, organizados em seis dimensões e treze itens de avaliação.
Em busca da (inter)nacionalização das produções científicas
Authors: Porto Junior Francisco Gilson Rebouças , Silva João Nunes da , Moraes Nelson Russo de 
Published: February 2016

A Revista Observatório publicada pelo Núcleo de Pesquisa e Extensão Observatório de Pesquisas Aplicadas ao Jornalismo e ao Ensino (OPAJE) da Universidade Federal do Tocantins (UFT) apresenta seu segundo número. Assim como declarado em seu número de abertura, a revista fortalece a política de acesso aberto da Universidade Federal do Tocantins (UFT), terceira maior universidade pública da Região Norte do Brasil. E é com esse foco, de crescimento, que a Revista Observatório, se debruçou sobre a divulgação das produções científicas em espaços internacionalizados. Reconhecemos que a despeito do dinamismo recente que a ciência brasileira vivencia e dos estímulos das agências de fomento, sobretudo do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), ainda somos limitados no âmbito global.
Arquivamento e preservação de longo prazo do arquivo em:
OpenDepot / Edina (The University of Edinburgh): http://opendepot.org/2712/
SSOAR-GESIS – Leibniz-Institut (Alemanha): http://www.ssoar.info/ssoar/handle/document/47040

Abrir em (para melhor visualização em dispositivos móveis - Formato Flipbooks):
Issuu / Calameo
“Publicar ou perecer”: um olhar sobre revistas de alto impacto e produções científicas emergentes
Authors: Porto Junior Francisco Gilson Rebouças , Moraes Nelson Russo de , Silva João Nunes da 
Published: February 2016

A Revista Observatório encerra o ano de 2015 com seu terceiro número publicado. Avanço e vitória na construção de uma proposta de um periódico que enfoca a transdiciplinaridade entre Comunicação, Jornalismo e Educação!
Lançamos nosso olhar sobre a máxima acadêmica "publicar ou perecer" (Publish or perish). Essa tem sido a pedra de toque que se tornou um verdadeiro dogma entre os pesquisadores e professores. Sobretudo em Ciências Sociais Aplicadas e Ciências Humanas, publicar é uma questão de sobrevivência acadêmica (principalmente, quando isso determina notoriedade, prestígio, reconhecimento e promoção de projetos e fontes de financiamento). Leia mais.
Arquivamento e preservação de longo prazo do arquivo em:
OpenDepot / Edina (The University of Edinburgh): http://opendepot.org/2696/
SSOAR-GESIS – Leibniz-Institut (Alemanha): http://www.ssoar.info/ssoar/handle/document/47075
Abrir em (para melhor visualização em dispositivos móveis - Formato Flipbooks):
Issuu / Calameo
Preparation Methods for Examining the ωo-Phase Formation in a β-Solidifying TiAl Alloy via Atom Probe Tomography
Authors: Schachermayer M. , Klein T. , Clemens H. , Mayer S. 
Published: February 2016

Abstract
Examinations with the atom probe are an excellent way to analyze all phases of a material on an atomic level, thus enabling a better understanding of their formation. This study aims to provide an appropriate method for the preparation of atom probe specimens made of multiphase intermetallic titanium aluminide alloys. With the help of a focused ion beam system and transmission kikuchi diffraction, tips of defined phases and phase interfaces were prepared, as is shown by the example of the ωo-Ti4Al3Nb phase, which is precipitated from the βo phase. The chemical composition of the two phases was determined by subsequent atom probe measurements which allowed to draw conclusions about the phase formation.
ACTIVE LONGITUDE AND SOLAR FLARE OCCURRENCES
Authors: Gyenge N. , Ludmány A. , Baranyi T. 
Published: February 2016

ABSTRACT
The aim of the present work is to specify the spatio-temporal characteristics of flare activity observed by the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) and the Geostationary Operational Environmental Satellite (GOES) in connection with the behavior of the longitudinal domain of enhanced sunspot activity known as active longitude (AL). By using our method developed for this purpose, we identified the AL in every Carrington Rotation provided by the Debrecen Photoheliographic Data. The spatial probability of flare occurrence has been estimated depending on the longitudinal distance from AL in the northern and southern hemispheres separately. We have found that more than 60% of the RHESSI and GOES flares is located within

from the AL. Hence, the most flare-productive active regions tend to be located in or close to the active longitudinal belt. This observed feature may allow for the prediction of the geo-effective position of the domain of enhanced flaring probability. Furthermore, we studied the temporal properties of flare occurrence near the AL and several significant fluctuations were found. More precisely, the results of the method are the following fluctuations: 0.8, 1.3, and 1.8 years. These temporal and spatial properties of the solar flare occurrence within the active longitudinal belts could provide us with an enhanced solar flare forecasting opportunity.
TETHER-CUTTING RECONNECTION BETWEEN TWO SOLAR FILAMENTS TRIGGERING OUTFLOWS AND A CORONAL MASS EJECTION
Authors: Chen Huadong , Zhang Jun , Li Leping , Ma Suli 
Published: February 2016

ABSTRACT
Triggering mechanisms of solar eruptions have long been a challenge. A few previous case studies have indicated that preceding gentle filament merging via magnetic reconnection may launch following intense eruption, according to the tether-cutting (TC) model. However, the detailed process of TC reconnection between filaments has not been exhibited yet. In this work, we report the high-resolution observations from the Interface Region Imaging Spectrometer (IRIS) of TC reconnection between two sheared filaments in NOAA active region 12146. The TC reconnection commenced on ∼15:35 UT on 2014 August 29 and triggered an eruptive GOES C4.3-class flare ∼8 minutes later. An associated coronal mass ejection appeared in the field of view of the Solar and Heliospheric Observatory/LASCO C2 about 40 minutes later. Thanks to the high spatial resolution of IRIS data, bright plasma outflows generated by the TC reconnection are clearly observed, which moved along the subarcsecond fine-scale flux tube structures in the erupting filament. Based on the imaging and spectral observations, the mean plane-of-sky and line-of-sight velocities of the TC reconnection outflows are separately measured to be ∼79 and 86 km s−1, which derives an average real speed of ∼120 km s−1. In addition, it is found that spectral features, such as peak intensities, Doppler shifts, and line widths in the TC reconnection region are evidently enhanced compared to those in the nearby region just before the flare.
Incidence of Infectious Morbidity Events after Second-Line Antiretroviral Therapy Initiation in HIV-Infected Adults in Yaoundé, Cameroon
Authors:   the 2LADY Study Group, Galy Adrien , Ciaff Laura , Le Moing Vincent , Eymard-Duvernay Sabrina , Abessolo Hermine , Toby Roselyne , Ayangma Liliane , Le Gac Sylvie , Mpoudi-Etame Mireille , Koulla-Shiro Sinata , Delaporte Eric , Cournil Amandine 
Published: February 2016

Background Since antiretroviral therapy (ART), HIV-infected individuals experience mainly non-AIDS-related conditions, among which infectious events are prominent. We aimed to estimate incidence and describe overall spectrum of infectious events, including all grade events, among HIV-1-infected adults failing first-line ART in Yaoundé, Cameroon. Methods All patients from Cameroon enrolled in the second-line ART 2LADY trial (ANRS12169) were included in this secondary analysis. Medical files were reviewed with predefined criteria for diagnosis assessment. Incidence rates (IR) were estimated per 100 person-years (% PY). Results A total of 302 adult patients contributing 840 PY experienced 596 infectious events (IR 71% PY). Only 29 (5%) events were graded as severe. Most frequent infections were upper respiratory tract infections (15% PY), diarrhoea (9% PY) and malaria (9% PY). A total of 369 (62%) infections occurred during the first year (IR 130% PY) followed by a persistent lower incidence during the following 3 years. Higher IR were observed in patients with CD4+ T-cell count ≤200 cells/mm3 for all infectious events except for mycobacterial and parasitic infections. IR of viral, bacterial and parasitic infectious events were lower in case of co-trimoxazole use in patients with CD4+ T-cell count ≤200 cells/mm3. Conclusions Infectious events are common and mainly occur during the first year after treatment initiation. Second-line ART initiation had a positive impact on the entire spectrum of infectious morbidity.
How to Motivate Patients with Rheumatoid Arthritis to Quit Smoking
Authors: Harris Helen E. , Tweedie Fiona , White Marie , Samson Kay 
Published: February 2016

Objective.Seropositive rheumatoid arthritis (RA) is strongly linked to cigarette smoking, and smoking cessation is an essential step in RA management. Our objectives were to develop RA and smoking awareness materials and to evaluate the influence of the materials on awareness about the links between RA and smoking and on motivation to quit smoking.Methods.A group of patients with seropositive RA in Fife, Scotland, were telephoned before the campaign, and the results of the precampaign questionnaire were used to develop the image for the campaign. After the campaign a second group of patients were questioned to ascertain the effect of the campaign.Results.The 320 patient responses to the precampaign questionnaire revealed that many ex-smokers with RA had quit when they developed a known smoking-related disease such as emphysema. This concept was used to develop an image illustrating that RA is a smoking-related disease. The campaign was launched in Fife in 2011. The postcampaign questionnaire involving 380 patients revealed that there was 21% higher awareness of a link between RA and smoking and 45% higher awareness that smoking could interfere with treatment of RA. In total, 13/75 smokers who had cut down since the campaign had been influenced by the new information.Conclusion.The new materials have successfully increased patients’ knowledge of the link between RA and smoking and the effect of smoking on RA therapy. RA smokers’ attitudes to smoking may have been affected by the campaign.
The Rate of Adherence to Antiarthritis Medications and Associated Factors among Patients with Rheumatoid Arthritis: A Systematic Literature Review and Metaanalysis
Authors: Scheiman-Elazary Anat , Duan Lewei , Shourt Courtney , Agrawal Harsh , Ellashof David , Cameron-Hay M. , Furst Daniel E. 
Published: February 2016

Objective.Reported adherence in rheumatoid arthritis (RA) varies widely (10.5–98.5%). Variability may result in part from different methods used to measure adherence. Our aims were to quantify adherence to antiarthritis medications for each method and to identify variability and associated factors.Methods.The systematic literature review examined PubMed, the Cochrane central database, and article reference lists from 1970 to November 2014. Papers with medication adherence data (disease-modifying antirheumatic drugs, steroids, and nonsteroidal antiinflammatory drugs) in adult patients with RA or data on associated factors were included. Adherence rate was recorded for each method. Random-effect metaanalysis estimated adherence for different evaluation methods.Results.Adherence rate was 66% (95% CI 0.58–0.75). There were no differences in adherence among different measurement methods (interview, questionnaires, etc.). Regression analysis showed that adherence decreases during followup. Among 100 possible factors potentially effecting adherence, 7 adherence-associated factors were found in at least 2 different studies. These were the use of infliximab compared with etanercept or methotrexate (MTX), use of MTX compared to sulfasalazine or to etanercept, belief in the necessity of the medications, older age, and white race.Conclusion.Overall adherence rate was 66%. We suggest that readers appraise adherence studies according to the medications evaluated, the validity of the method, and the scales and cutpoints.
Effect of Rheumatoid Arthritis on Longterm Sickness Absence in 1994-2011: A Danish Cohort Study
Authors: Hansen Sofie Mandrup , Hetland Merete Lund , Pedersen Jacob , Østergaard Mikkel , Rubak Tine Steen , Bjorner Jakob Bue 
Published: February 2016

Objective.By linkage of national registries, we investigated the risk of longterm sickness absence (LTSA) ≥ 3 weeks in a large cohort of Danish patients with rheumatoid arthritis (RA) and non-patients. The study aimed to (1) estimate the risk of LTSA for patients with RA compared with the general population, (2) examine whether the risk of LTSA has changed in recent years, and (3) evaluate the effect of other risk factors for LTSA (e.g., physical work demands, age, sex, education, and psychiatric and somatic comorbidities).Methods.A total of 6677 patients with RA aged 18–59 years in the years 1994–2011 were identified in registries and compared with 56,955 controls from the general population matched by age, sex, and city size. The risk of LTSA was analyzed using Cox proportional hazards models with late entry, controlling for other risk factors and assuming separate risks in the first year after diagnosis and the following years.Results.Compared with the general population, patients with RA had increased risk of LTSA in the first year after diagnosis (HR 5.4 during 1994–1999, 95% CI 4.2–6.8) and in following years (HR 2.4, 95% CI 2.1–2.8). For established RA (> 1 yr after diagnosis), the excess was 20% lower in 2006–2011 (HR 1.9, 95% CI 1.7–2.2) compared with 1994–1999 (p < 0.001). For patients with RA and controls, older age, shorter education, a physically demanding job, and somatic and/or psychiatric comorbidities increased the risk of LTSA.Conclusion.While improvements were observed from 1994–1999 to 2006–2011, patients with RA have significant increased risk of LTSA, in particular in the first year after diagnosis.
Assessment of Fatigue in Spondyloarthritis and Its Association with Disease Activity
Authors: López-Medina Clementina , Schiotis Ruxandra Elena , Font-Ugalde Pilar , Castro-Villegas Maria Carmen , Calvo-Gutiérrez Jerusalem , Ortega-Castro Rafaela , Jiménez-Gasco Rocío , Escudero-Contreras Alejandro , Collantes-Estévez Eduardo ,   On behalf of the REGISPONSER Working Group
Published: February 2016

Objective.To evaluate fatigue in patients with spondyloarthritis (SpA) and to define its association with disease-related factors and patients’ features.Methods.A cross-sectional multicenter study which includes 2251 patients with SpA selected from the national Spondyloarthropathies Registry (the Spanish Society of Rheumatology; REGISPONSER) Spanish cohort. The primary outcome was the assessment of fatigue performed with the first item of the Bath Ankylosing Spondyloarthritis Disease Activity Index followed by the study of its relation with different factors organized into 4 groups: sociodemographics, emotional, disease-related, and disease activity. Univariate logistic regressions, multivariate logistic regression, and multiple linear regressions were performed to relate fatigue with the studied covariates.Results.Mean fatigue score in all patients with SpA was 4.3 ± 2.9, with statistically significant differences between different SpA types. In univariate logistic regressions, significant differences were seen for many variables included in the 4 groups. Multivariate logistic regression showed that high fatigue score was related with sex (female), emotional component, the Ankylosing Spondylitis Quality of Life score, stiffness, and high levels of 2 visual analog scale items (vertebral pain in the last week and patient’s global assessment of disease activity). The multivariate linear regression showed that fatigue was mainly explained by disease-related factors and disease activity (54.1%), but sex and emotional status may also be involved in 13.5% of the variance.Conclusion.Fatigue is associated with disease-related factors and mostly with SpA activity. However, the emotional component and sex may contribute to the onset of fatigue.
Modified Framingham Risk Factor Score for Systemic Lupus Erythematosus
Authors: Urowitz Murray B. , Ibañez Dominique , Su Jiandong , Gladman Dafna D. 
Published: February 2016

Objective.The traditional Framingham Risk Factor Score (FRS) underestimates the risk for coronary artery disease (CAD) in patients with systemic lupus erythematosus (SLE). We aimed to determine whether an adjustment to the FRS would more accurately reflect the higher prevalence of CAD among patients with SLE.Methods.Patients with SLE without a previous history of CAD or diabetes followed regularly at the University of Toronto Lupus Clinic were included. A modified FRS (mFRS) was calculated by multiplying the items by 1.5, 2, 3, or 4. In the first part of the study, using one-third of all eligible patients, we evaluated the sensitivity and specificity of the FRS and the different multipliers for the mFRS. In the second part of the study, using the remaining 2/3 of the eligible patients, we compared the predictive ability of the FRS to the mFRS. In the third part of the study, we assessed the prediction for CAD in a time-dependent analysis of the FRS and mFRS.Results.There were 905 women (89.3%) with a total of 95 CAD events included. In part 1, we determined that a multiplier of 2 provided the best combination of sensitivity and specificity. In part 2, 2.4% of the patients were classified as moderate/high risk based on the classic FRS and 17.3% using the 2FRS (the FRS with a multiplier of 2). In part 3, a time-dependent covariate analysis for the prediction of the first CAD event revealed an HR of 3.22 (p = 0.07) for the classic FRS and 4.37 (p < 0.0001) for the 2FRS.Conclusion.An mFRS in which each item is multiplied by 2 more accurately predicts CAD in patients with SLE.
Low Risk of Hepatitis B Virus Reactivation in HBsAg-negative/Anti-HBc–positive Carriers Receiving Rituximab for Rheumatoid Arthritis: A Retrospective Multicenter Italian Study
Authors: Varisco Valentina , Viganò Mauro , Batticciotto Alberto , Lampertico Pietro , Marchesoni Antonio , Gibertini Patrizia , Pellerito Raffaele , Rovera Guido , Caporali Roberto , Todoerti Monica , Covelli Michele , Notarnicola Antonella , Atzeni Fabiola , Sarzi-Puttini Piercarlo 
Published: February 2016

Objective.Patients with resolved hepatitis B virus (HBV) infection, i.e., hepatitis B surface antigen (HBsAg)-negative/antihepatitis B core antigen (anti-HBc)-positive, undergoing rituximab (RTX)-based chemotherapy for hematological malignancies without anti-HBV prophylaxis are at risk of HBV reactivation, but the risk in such patients receiving RTX for rheumatological disorders is not clear. We evaluated this risk in HBsAg-negative/anti-HBc–positive patients with rheumatoid arthritis (RA) undergoing RTX without prophylaxis.Methods.Thirty-three HBsAg-negative/anti-HBc–positive outpatients with RA with undetectable HBV DNA by sensitive PCR assay [73% women, median age 60 years, 85% with HBsAg antibodies (anti-HBs), 37% with antihepatitis B envelope antigen] received a median of 3 cycles of RTX (range 1–8) over 34 months (range 0–80) combined with disease-modifying antirheumatic drugs (DMARD) without prophylaxis. All underwent clinical and laboratory monitoring during and after RTX administration, including serum HBsAg and HBV DNA measurements every 6 months or whenever clinically indicated.Results.None of the patients seroreverted to HBsAg during RTX treatment, but 6/28 (21%) showed a > 50% decrease in protective anti-HBs levels, including 2 who became anti-HBs–negative. One patient (3%) who became HBV DNA-positive (44 IU/ml) after 6 months of RTX treatment was effectively rescued with lamivudine before any hepatitis flare occurred. Among the 14 patients monitored for 18 months (range 0–70) after RTX discontinuation, no HBV reactivation was observed.Conclusion.The administration of RTX + DMARD in patients with RA with resolved HBV infection leads to a negligible risk of HBV reactivation, thus suggesting that serum HBsAg and/or HBV DNA monitoring but not universal anti-HBV prophylaxis is justified.