bluuebunny/crossref_metadata_2025_split huggingface dataset:
Final report, on-going key comparison BIPM.QM-K1, ozone at ambient level, comparison with ISCIII, March 2017
Authors: Viallon Joële , Moussay Philippe , Idrees Faraz , Wielgosz Robert , Sanchez Carmen , Gomez Pilar Morillo 
Published: August 2017

As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Effects of the National Bioengineered Food Disclosure Standard: Willingness To Pay for Labels that Communicate the Presence or Absence of Genetic Modification
Authors: McFadden Brandon R , Lusk Jayson L 
Published: August 2017

AbstractAfter much debate, the United States recently adopted a law that will require mandatory labeling of genetically modified (GM) food. We elicit willingness‐to‐pay (WTP) for manufactured and fresh foods that communicate the presence or absence of GM material. We find that a text disclosing the presence of GM material lowers WTP relative to a QR code disclosure that must be scanned. Furthermore, participants perceive Non‐GMO Project verified and organic as substitutes; WTP premiums for a product with both Non‐GMO Project verified and organic labels is about the same as the WTP premium when either label is present in isolation.
Occupational Exposure to Manganese and Fine Motor Skills in Elderly Men: Results from the Heinz Nixdorf Recall Study
Authors: Pesch Beate , Casjens Swaantje , Weiss Tobias , Kendzia Benjamin , Arendt Marina , Eisele Lewin , Behrens Thomas , Ulrich Nadin , Pundt Noreen , Marr Anja , Robens Sibylle , Van Thriel Christoph , Van Gelder Rainer , Aschner Michael , Moebus Susanne , Dragano Nico , Brüning Thomas , Jöckel Karl-Heinz 
Published: August 2017

Abstract

Objectives
Exposure to manganese (Mn) may cause movement disorders, but less is known whether the effects persist after the termination of exposure. This study investigated the association between former exposure to Mn and fine motor deficits in elderly men from an industrial area with steel production.

Methods
Data on the occupational history and fine motor tests were obtained from the second follow-up of the prospective Heinz Nixdorf Recall Study (2011–2014). The study population included 1232 men (median age 68 years). Mn in blood (MnB) was determined in archived samples (2000–2003). The association between Mn exposure (working as welder or in other at-risk occupations, cumulative exposure to inhalable Mn, MnB) with various motor functions (errors in line tracing, steadiness, or aiming and tapping hits) was investigated with Poisson and logistic regression, adjusted for iron status and other covariates. Odds ratios (ORs) with 95% confidence intervals (CIs) were estimated for substantially impaired dexterity (errors >90th percentile, tapping hits <10th percentile).

Results
The median of cumulative exposure to inhalable Mn was 58 µg m–3 years in 322 men who ever worked in at-risk occupations. Although we observed a partly better motor performance of exposed workers at group level, we found fewer tapping hits in men with cumulative Mn exposure >184.8 µg m–3 years (OR 2.15, 95% CI 1.17–3.94). MnB ≥ 15 µg l–1, serum ferritin ≥ 400 µg l–1, and gamma-glutamyl transferase ≥74 U l–1 were associated with a greater number of errors in line tracing.

Conclusions
We found evidence that exposure to inhalable Mn may carry a risk for dexterity deficits. Whether these deficits can be exclusively attributed to Mn remains to be elucidated, as airborne Mn is strongly correlated with iron in metal fumes, and high ferritin was also associated with errors in line tracing. Furthermore, hand training effects must be taken into account when testing for fine motor skills.
clustComp, a bioconductor package for the comparison of clustering results
Authors: Torrente Aurora , Brazma Alvis 
Published: August 2017

Abstract

Summary
clustComp is an open source Bioconductor package that implements different techniques for the comparison of two gene expression clustering results. These include flat versus flat and hierarchical versus flat comparisons. The visualization of the similarities is provided by means of a bipartite graph, whose layout is heuristically optimized. Its flexibility allows a suitable visualization for both small and large datasets.

Availability and implementation
The package is available at http://bioconductor.org/packages/clustComp/ and contains a ‘vignette’ outlying the typical use of the algorithms.

Supplementary information
Supplementary data are available at Bioinformatics online.
fastBMA: scalable network inference and transitive reduction
Authors: Hung Ling-Hong , Shi Kaiyuan , Wu Migao , Young William Chad , Raftery Adrian E. , Yeung Ka Yee 
Published: August 2017

Abstract
Inferring genetic networks from genome-wide expression data is extremely demanding computationally. We have developed fastBMA, a distributed, parallel, and scalable implementation of Bayesian model averaging (BMA) for this purpose. fastBMA also includes a computationally efficient module for eliminating redundant indirect edges in the network by mapping the transitive reduction to an easily solved shortest-path problem. We evaluated the performance of fastBMA on synthetic data and experimental genome-wide time series yeast and human datasets. When using a single CPU core, fastBMA is up to 100 times faster than the next fastest method, LASSO, with increased accuracy. It is a memory-efficient, parallel, and distributed application that scales to human genome-wide expression data. A 10 000-gene regulation network can be obtained in a matter of hours using a 32-core cloud cluster (2 nodes of 16 cores). fastBMA is a significant improvement over its predecessor ScanBMA. It is more accurate and orders of magnitude faster than other fast network inference methods such as the 1 based on LASSO. The improved scalability allows it to calculate networks from genome scale data in a reasonable time frame. The transitive reduction method can improve accuracy in denser networks. fastBMA is available as code (M.I.T. license) from GitHub (https://github.com/lhhunghimself/fastBMA), as part of the updated networkBMA Bioconductor package (https://www.bioconductor.org/packages/release/bioc/html/networkBMA.html) and as ready-to-deploy Docker images (https://hub.docker.com/r/biodepot/fastbma/).
A diverse group of echogenic particles observed with a broadband, high frequency echosounder
Authors: Briseño-Avena Christian , Franks Peter J S , Roberts Paul L D , Jaffe Jules S 
Published: August 2017

Abstract
In 1980, Holliday and Pieper stated: “Most sound scattering in the ocean volume can be traced to a biotic origin.” However, most of the bioacoustics research in the past three decades has focused on only a few groups of organisms. Targets such as small gelatinous organisms, marine snow, and phytoplankton, e.g. have been generally to be considered relatively transparent to acoustic waves due to their sizes and relatively low sound speed and density contrasts relative to seawater. However, using a broadband system (ZOOPS-O2) we found that these targets contributed significantly to acoustic returns in the 1.5–2.5 MHz frequency range. Given that phytoplankton and marine snow layers are ubiquitous features of coastal regions; this works suggests that they should be considered as potential sources of backscatter in biological acoustic surveys.
Do not shoot the messenger: ICES advice for an ecosystem approach to fisheries management in the European Union
Authors: Ballesteros Marta , Chapela Rosa , Ramírez-Monsalve Paulina , Raakjaer Jesper , Hegland Troels J , Nielsen Kåre N , Laksá Unn , Degnbol Poul 
Published: August 2017

AbstractThe International Council for the Exploration of the Sea (ICES) occupies a central role in the advice system to support the implementation of an ecosystem approach to fisheries management (EAFM) in the European Union (EU). Despite improvements, its capacity to deliver ecosystem advice seems to be far from a fully functional operational framework. To what extent availability of appropriate scientific advice is a barrier for a more widespread use of an EAFM in Europe remains an open question. Building on the findings of a large research project, this article explores what advice ICES can provide. The article concludes that: (i) ICES has taken a leading role in generating an EAFM framework in which management decisions can operate; (ii) the advice “suppliers” and the advice “users” agree on the feasibility of using existing knowledge to “do EAFM now”; (iii) ICES can address a range of shortcomings, but some of the present bottlenecks demand concerted action between the advisory system and the political realm. The implementation of an EAFM requires consistency between science and management. ICES appears as well-suited to facilitate the dialogue on applying an EAFM in the EU, but it is unrealistic to expect ICES to produce all the answers.
Beyond Employment Tribunals: Enforcement of Employment Rights by EU-8 Migrant Workers
Authors: Barnard Catherine , Ludlow Amy , Fraser Butlin Sarah 
Published: August 2017

Abstract
Many EU-8 migrant workers work in low-skilled, low-paid jobs, particularly in sectors such as food processing and agriculture. Our interest lies in the experience of those migrant workers in the UK and specifically what happens when they are denied their employment rights. In earlier work, we have already shown that there was a significant underuse by EU-8 migrant workers of Employment Tribunals (ETs). So the questions for this article are three-fold. First, why do so few EU-8 migrant workers enforce their employment rights before ETs and to what extent do legal, economic, political and cultural landscapes, as they are experienced by migrant workers, constrain or enable enforcement action? Second, if migrant workers do not resort to ETs, what do they do? Do they simply move on, or do they use alternative enforcement mechanisms (such as the Gangmasters’ Licensing Authority)? How effective are these other enforcement processes and institutions in protecting the rights of migrant and similarly vulnerable domestic workers? And third, what might be done to improve the enforcement of employment rights for EU-8 migrant workers and for other vulnerable workers on the UK labour market, including non-EU migrants, especially in the light of the new labour market enforcement agency (LMEA)? We argue that the establishment of a Pay and Work Rights Ombudsman might help address some of the problems experienced by EU-8 migrant workers and other vulnerable national workers.
Effects of computerized decision support system implementations on patient outcomes in inpatient care: a systematic review
Authors: Varghese Julian , Kleine Maren , Gessner Sophia Isabella , Sandmann Sarah , Dugas Martin 
Published: August 2017

AbstractObjectivesTo systematically classify the clinical impact of computerized clinical decision support systems (CDSSs) in inpatient care.Materials and MethodsMedline, Cochrane Trials, and Cochrane Reviews were searched for CDSS studies that assessed patient outcomes in inpatient settings. For each study, 2 physicians independently mapped patient outcome effects to a predefined medical effect score to assess the clinical impact of reported outcome effects. Disagreements were measured by using weighted kappa and solved by consensus. An example set of promising disease entities was generated based on medical effect scores and risk of bias assessment. To summarize technical characteristics of the systems, reported input variables and algorithm types were extracted as well.ResultsSeventy studies were included. Five (7%) reported reduced mortality, 16 (23%) reduced life-threatening events, and 28 (40%) reduced non–life-threatening events, 20 (29%) had no significant impact on patient outcomes, and 1 showed a negative effect (weighted κ: 0.72, P &lt; .001). Six of 24 disease entity settings showed high effect scores with medium or low risk of bias: blood glucose management, blood transfusion management, physiologic deterioration prevention, pressure ulcer prevention, acute kidney injury prevention, and venous thromboembolism prophylaxis. Most of the implemented algorithms (72%) were rule-based. Reported input variables are shared as standardized models on a metadata repository.Discussion and ConclusionMost of the included CDSS studies were associated with positive patient outcomes effects but with substantial differences regarding the clinical impact. A subset of 6 disease entities could be filtered in which CDSS should be given special consideration at sites where computer-assisted decision-making is deemed to be underutilized.Registration number on PROSPERO: CRD42016049946.
It’s all in the timing: calibrating temporal penalties for biomedical data sharing
Authors: Xia Weiyi , Wan Zhiyu , Yin Zhijun , Gaupp James , Liu Yongtai , Clayton Ellen Wright , Kantarcioglu Murat , Vorobeychik Yevgeniy , Malin Bradley A 
Published: August 2017

Abstract

Objective
Biomedical science is driven by datasets that are being accumulated at an unprecedented rate, with ever-growing volume and richness. There are various initiatives to make these datasets more widely available to recipients who sign Data Use Certificate agreements, whereby penalties are levied for violations. A particularly popular penalty is the temporary revocation, often for several months, of the recipient’s data usage rights. This policy is based on the assumption that the value of biomedical research data depreciates significantly over time; however, no studies have been performed to substantiate this belief. This study investigates whether this assumption holds true and the data science policy implications.

Methods
This study tests the hypothesis that the value of data for scientific investigators, in terms of the impact of the publications based on the data, decreases over time. The hypothesis is tested formally through a mixed linear effects model using approximately 1200 publications between 2007 and 2013 that used datasets from the Database of Genotypes and Phenotypes, a data-sharing initiative of the National Institutes of Health.

Results
The analysis shows that the impact factors for publications based on Database of Genotypes and Phenotypes datasets depreciate in a statistically significant manner. However, we further discover that the depreciation rate is slow, only ∼10% per year, on average.

Conclusion
The enduring value of data for subsequent studies implies that revoking usage for short periods of time may not sufficiently deter those who would violate Data Use Certificate agreements and that alternative penalty mechanisms may need to be invoked.
Developing a tool for identifying high-risk employers for inspection
Authors: Chao T-K , Sun C , Beach J R 
Published: August 2017

AbstractBackgroundWorkers’ Compensation Board (WCB) data and other information are sometimes used to calculate an ‘Occupational Health and Safety (OHS) index’ as a way of identifying businesses considered ‘high risk’ to be inspected as part of enforcement work. However, no evidence on the validity of this index exists.AimsTo evaluate the performance of the Alberta OHS index, a ‘score’ based largely on WCB claims data, and to see if an index calculated using different information could perform better.MethodsData from the Alberta Compliance Management Information System database, 2011–2015, and WCB claim database, 2007–2014, were retrieved. Issuing ‘stop work’ or ‘stop use’ orders in inspections was defined as a proxy of high-risk outcome. The performance of the current and a modified OHS index were assessed using receiver operating characteristics (ROC) and regression analyses.ResultsIn large employers, neither the current nor the modified OHS index was particularly effective in identifying ‘high risk’ employers with the area under the ROC curve (AROC) of 0.55 (95% confidence interval [CI] 0.52–0.57; P &lt; 0.001) and 0.59 (95% CI 0.57–0.62; P &lt; 0.001), respectively. In small employers, neither index seemed very effective with an AROC of 0.54 (95% CI 0.53–0.56; P &lt; 0.001) and 0.55 (95% CI 0.53–0.56; P &lt; 0.001), respectively. These results were consistent in subgroup analyses of assignments without specific initiatives, both in large and small employers.ConclusionsNeither the current nor a modified OHS index seemed to effectively identify high-risk employers. Heterogeneous results in large and small employers suggest that approaches to different-sized employers are appropriate.
Modelling transient states in language change
Authors: Postma Gertjan 
Published: August 2017

AbstractModels of language change may include, apart from the initial and terminal state, an intermediate state T. Building further on Postma (2010), who observed that the dynamics of the transient state T (’failed change’) is algebraically related to the overall change A → B (the former is the first derivative of the latter), we present a generalized algebraic model that includes both the failed change A → B and the successful change A → B. We first generalize the two-state logistic function of A → B to a differential equation (DE) that represents the underlying processes. This DE has a bundle of time shifted logistic curves as its solution. This derives Kroch’s Constant Rate Effect. By modifying this DE, we describe the dynamics of the entire A → T → B process, i.e. we develop a model that includes both the successful and the failed change. The algebraic link between failed change and successful change turns out to be an approximation.
Lost and Regained in Translation
Authors: Sherry Beverley 
Published: August 2017

Abstract
This chapter argues that the translation of poetry can work as an instrument to identify the genius of the original poem, in particular to single out aural effects that are part of meaning and are lost in translation. First, the longstanding controversy over whether it is possible to translate poetry is addressed: while Frost’s dictum that ‘poetry is what is lost in translation’ provides a starting point, the theories of Dryden and Steiner are fundamental to the enquiry. Three translations of Paradise Lost are examined: two interlingual versions, the German of Haak (1681) and the French of Himy (2001), and the intralingual translation by Danielson (2008). The foreign-language versions throw light on Milton’s original by way of shock effect, while Danielson’s English paraphrase offers an opportunity to distinguish minute sound effects that are part of the poem’s meaning and central to Milton’s genius.
‘Translated Verse’
Authors: Haan Estelle 
Published: August 2017

Abstract
This chapter discusses a cluster of English verse translations of Milton’s Poemata that emerged in the long eighteenth century. Focusing on versions by Symmons, Cowper, and, to a lesser degree, Strutt and others, it foregrounds a variety of contexts—biographical, literary, discursive—that engendered, it is argued, an intellectual discourse on translational methodology that is still relevant today. It is a discourse, moreover, that raises a host of important theoretical questions: about the nature and function of translation; the viability of rendering a neo-Latin source text in a target language; the potential ‘fetters’ that, in Drydenesque terms, might constrain ‘the Verbal Copyer’, or perhaps the quasi-liberating fluency, described by Venuti as the ‘fluent strategy’, attendant upon recourse to verse as translational medium.
Paradise Lost in Dutch, 1728–2003
Authors: Dijkhuizen Jan Frans van 
Published: August 2017

Abstract
This chapter offers a history of Dutch translations of Paradise Lost, from the early eighteenth to the early twenty-first century. The focus is on the question of how Dutch translators have grappled with two issues: the epic’s verse form, especially its lack of rhyme and syntactic idiosyncrasies; and its politico-religious dimension, its complex view of the relationship between earthly and divine authority, as well as its anti-predestinarian stance. The history of Paradise Lost in Dutch, which starts with the translation of Van Zanten in 1728, is characterized by an unresolved formal struggle with Milton’s blank verse, embraced unreservedly only in the early twentieth century, with translator Gutteling. Before 1900, the politico-religious dimension of Paradise Lost was at the fore for translators, yet this aspect of the poem has receded in prominence, with translators after 1900 presenting the poem instead as a timeless and self-contained work of literary genius.
A Vision in Times of Need
Authors: Lange Anne 
Published: August 2017

Abstract
This chapter outlines Estonian translations of Milton’s works and their socio-cultural context in order to reveal the translators as writers keenly aware of the value of their translations as weapons of communication trained on their environment. All three translations—the prose translation of Paradise Lost and Paradise Regained in 1895, the verse translation of the beginning of book 3 of Paradise Lost in 1962, and the 1974 translation of Areopagitica—were done under the circumstance of censorship practised in Estonia by either Russian or Soviet authorities. The 1895 translation was read in an atmosphere of late national awakening when Estonians were trying to find a way to restore their ‘paradise’ of independence. The 1962 verse translation was published in the hope of consciously influencing the moral attitude of its readers. The 1974 translation of Areopagitica highlighted the absurdities of Soviet book production.
Iceland’s Milton
Authors: Eysteinsson Ástráður 
Published: August 2017

Abstract
Milton’s presence in Icelandic letters is largely limited to Jón Þorláksson’s translation of Paradise Lost, the first books of which were published in 1794–6. This translation is arguably one of the stepping stones in Icelandic literary history, emerging at a critical crossing point of Icelandic literary heritage, religious literacy, and a developing secular culture born of the Enlightenment and quickly heading towards Romanticism. This chapter analyses the historical and cultural context of Þorláksson’s enterprise; why he translated Milton through intermediary translations (Danish and German); why and with what results he opted for the Icelandic fornyrðislag metre, apparently so different from Milton’s blank verse; and how he actively delved into the language and material of Norse myths and medieval Icelandic literature in coming to terms with Milton’s classical and biblical discourse—in a translational dialogue that proved vital for Þorláksson’s successors, the Romantic poets who are often seen as rejuvenating Icelandic literature.