bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long‐Term Outcome of Catheter Ablation for Atrial Fibrillation in Patients With Apical Hypertrophic Cardiomyopathy
Authors: ROH SEUNG‐YOUNG , KIM DONG‐HYEOK , AHN JINHEE , LEE KWANG NO , LEE DAE IN , SHIM JAEMIN , CHOI JONG‐IL , PARK SANG‐WEON , KIM YOUNG‐HOON 
Published: April 2016

Atrial Fibrillation in Apical Hypertrophic CardiomyopathyIntroductionAtrial fibrillation (AF) is a common manifestation in cases of hypertrophic cardiomyopathy (HCM). Catheter ablation (CA) for AF in patients with asymmetric septal HCM (SeHCM) is selectively effective and often needs a repeat procedure. Apical HCM (ApHCM) has a better prognosis than SeHCM. However, the outcome of CA for AF in patients with ApHCM is unclear.Methods and resultsEighteen patients with ApHCM (ApHCM group) and 13 SeHCM patients (SeHCM group) underwent CA for AF. Ninety sex‐, age‐, and AF type‐matched non‐HCM patients who underwent CA for AF were selected as controls (5 controls for each ApHCM patient). During a median follow‐up of 44.7 ± 30.8 months, 50% of the patients remained free from AF/atrial tachycardia (AT) in the ApHCM group. The ApHCM patients displayed enlarged left atrial (LA) diameter (47.1 ± 6.0 mm vs. 42.4 ± 5.5 mm, P = 0.006) and increased E/Ea ratio (13.5 ± 4.4 vs. 9.1 ± 3.1, P < 0.001) as compared to the control group. In contrast, the mean LA diameter and E/Ea ratio of the ApHCM group were not different than those of the SeHCM group. The overall freedom from AF/AT in the ApHCM group was significantly worse than in the control group (log rank P = 0.028), but there was no difference between the ApHCM and SeHCM groups (P = 0.831). High LA diameter index ≥25 mm/m2 (HR 12.8, 95% CI [1.2–142.1]; P = 0.037) was an independent predictor of AF/AT recurrence among patients with ApHCM.ConclusionLong‐term outcome of CA for AF was worse in patients with ApHCM, as compared to controls, but was similar to patients with SeHCM.
Parental death during childhood and depression in young adults – a national cohort study
Authors: Berg Lisa , Rostila Mikael , Hjern Anders 
Published: April 2016

BackgroundThere are few prospective, population‐based studies on childhood parental death and psychiatric disorders in adulthood, and previous findings are inconclusive. This study investigated the association between parental death from natural and external (suicides, accidents or homicides) causes before 18 years and the risk of clinical depression in young adults, in relation to age at loss and gender of both child and parent.MethodsIn this register‐based study, a national cohort born in Sweden during 1973–1982 (n = 862,554) was followed with regard to hospital admissions and outpatient care for depression during 2006–2013. Multivariate Cox proportional hazards models were used to estimate the impact of parental death, taking sociodemographic and parental psychosocial covariates into account.ResultsMaternal death from natural causes was associated with a hazard ratio (HR) of outpatient care for depression of 1.19 [95% confidence interval (CI), 1.02–1.40] in men and 1.15 (1.01–1.31) in women, after adjustment for sociodemographic confounders, with similar effect sizes for paternal natural death. Death from external causes consistently had higher effect size compared with natural deaths, in particular in relation to risk of hospital admissions for depression where they were as high as HR 3.23 (2.38–4.38) for men, and 1.79 (1.30–2.47) for women after a loss of a mother. Losing a parent in preschool age, compared with losing a parent as a teenager, was associated with higher risks of both hospitalization (p = .006) and outpatient care (p = .001) for depression.ConclusionsThis study indicates that parental loss to death from natural causes during childhood is associated with a small increased risk of long‐term consequences for psychological health. Children who lose their parents to death from external causes, that is suicides, accidents or homicides, and children losing a parent in young ages are, however, at particular risk and should be given priority in preventive interventions after parental loss.
Influence of Tooth Preparation Design on Fitting Accuracy of CAD‐CAM Based Restorations
Authors: Ates Sabit Melih , Yesil Duymus Zeynep 
Published: April 2016

AbstractObjectiveThe purpose of this study was to evaluate the marginal fit of different zirconia and metal frameworks and compare them with each other on different finish line configurations.Materials and Methods20 stainless steel dies 10 with shoulder and 10 with chamfer finish line including 6 mm preparation height and 3 degree axial angle simulating a 6 degree total occlusal covergence of the prepared tooth were produced. After embedding the each group of die into the arch‐shaped acrylic resin blocks, impressions were made using silicone based impression material and 120 casts were prepared subsequently. The dies were divided into six groups each having 20 specimens (10 with shoulder, 10 with chamfer finish line). Group CM consisted of Co‐Cr produced by conventional casting procedure, group MM of Co‐Cr prepared by metal milling, group LM of Co‐Cr prepared by direct laser metal sinterization (DLMS), group ZZ of Zirkonzahn (Zirkonzahn GmbH, Gais, Italy), group LZ of Lava Zirconia (3 M ESPE Dental AG, Seefeld, Germany) and group DZ of DC‐Zirkon (DCS Dental AG, Allschwil, Switzerland). Stereomicroscope were used to evaluate the marginal fit of frameworks and marginal gap values obtained from the images were analyzed using Mann–Whitney U Test and Kruskal–Wallis H Test with Bonferroni correction.ResultsThe lowest value of marginal gap was identified in the samples from the LZ group and the highest value was identified in those from ZZ in both finish lines. The effect of finish lines was not significant for most groups but CM frameworks with chamfer finish lines and the DZ frameworks with shoulder finish lines showed significantly lower marginal gap values.ConclusionThe marginal gaps of the various tested zirconia and metal framework were within the range of clinical acceptability (120 µm).Clinical SignificanceThe results of this in vitro study suggest that margin preparation design and type of zirconia and metal framework materials for various CAD‐CAM systems have a significant effect on marginal fit of the resulting restorations. (J Esthet Restor Dent 28:238–246, 2016)
Parents’ Perspectives on Supporting Their Decision Making in Genome‐Wide Sequencing
Authors: Li Karen C. , Birch Patricia H. , Garrett Bernard M. , MacPhee Maura , Adam Shelin , Friedman Jan M. 
Published: April 2016

AbstractPurposeThe purpose of this study was to explore parents’ perceptions of their decisional needs when considering genome‐wide sequencing (GWS) for their child. This is a partial report and focuses on how parents prefer to receive education and information to support their decision making about GWS.DesignThis study adopted an interpretive description qualitative methodological approach and used the concept of shared decision making and the Ottawa Decision Support Framework.MethodsParticipants were parents who had already consented to GWS, and had children with undiagnosed conditions that were suspected to be genetic in origin. Fifteen parents participated in a focus group or individual interview. Transcriptions were analyzed concurrently with data collection, iteratively, and constantly compared to one another. Repeat interviews were conducted with five of the parents to confirm, challenge, or expand on the developing concepts.FindingsParticipants felt that their decision to proceed with GWS for their child was an easy one. However, they expressed some unresolved decisional needs, including a lack of knowledge about certain topics that became relevant and important to them later and a need for more support and resources. Participants also had ongoing informational and psychosocial needs after the single clinical encounter where their decision making occurred.ConclusionsParticipants expressed unmet decisional needs, which may have influenced the quality of their decisions. The strategies that participants suggested may help create parent‐tailored education, counseling, decision support, and informed consent processes.Clinical RelevanceHealth care professionals who offer GWS for children should assess parents’ values, priorities, and informational needs and tailor information accordingly. There are opportunities for nurses to become involved in supporting families who are considering GWS for their child.
Correlation of serum ANA and direct immunofluorescence studies in elderly Thai patients with red and white oral lesions
Authors: Thongprasom Kobkan , Prapinjumrune Chanwit , Kanjanabuch Patnarin , Youngnak‐Piboonratanakit Pornpan , Preuksrisakul Titipong 
Published: April 2016

ObjectivesThis study investigated the presence of serum antinuclear antibodies (ANA) profile and direct immunofluorescence (DIF) evaluation in elderly Thai patients with red and white oral lesions.Materials and MethodsThirty‐two patients with red and white oral lesions were divided into two groups: group I consisted of 10 cases not taking medications, while group II consisted of 12 cases taking medications, and 30 healthy subjects as a control group. Blood samples were used to determine the ANA profile. DIF was investigated in the lesion containing groups.ResultsSerum ANA was found in six cases (60%) in group I, eight cases (66.7%) in group II, and 19 cases (63.3%) in the control group. There were no significant differences between group I and group II and the control group (P > 0.05). Serum ANA was most commonly found in patients taking hypolipidemics (80%), followed by antihypertensives (71.4%), NSAIDs (50%), hypoglycemics (50%), and others (66.7%). The anticytoplasmic staining frequency in group II was higher compared with group I and the control group. Anti‐dsDNA antibodies were not found in any group.ConclusionsElderly patients with red and white oral lesions who were taking medications had a higher serum ANA frequency than group I and the control group.
Association of Neutral Zone Position with Age, Gender, and Period of Edentulism
Authors: Porwal Amit , Satpathy Anurag , Jain Preet , Ponnanna Ajjikuttira Appanna 
Published: April 2016

AbstractPurposeThe changing dynamics of an aging mouth influence the position of the neutral zone (NZ). While the advantage of the NZ concept in complete denture treatment is quite established, what is not clearly understood is its position in relation to the crest of the residual ridge due to conflicting reports from previous studies. The purpose of this study was to investigate the distance and direction of NZ position in relation to crest of the residual ridge in edentulous patients and its association with age, gender, and period of edentulism.Materials and MethodsA cross‐sectional study was conducted in 133 patients (70 males, 63 females) with a mean age of 58.81 ± 11.78 years. NZ recording was done using admix material by following standard procedures. Two metallic wires were adapted, one on the ridge and another on the center of the occlusal rims, and standardized digital radiographs were made. The position of NZ in relation to the crest of the residual ridge was recorded by noting the direction and measuring the distance between the adapted wires digitally at five locations (right molar, right premolar, incisor, left molar, left premolar regions).ResultsAge, gender, and period of edentulism had no significant association with the position of NZ. No specific trend was observed in the in NZ position with a non‐significant correlation.ConclusionsDistance and the direction of neutral zone position in relation to crest of the residual ridge in edentulous patients bear no significant relationship with factors such as age, gender, and period of edentulism.
Costs and Risk of Catfish Split‐pond Systems
Authors: Kumar Ganesh , Engle Carole , Tucker Craig 
Published: April 2016

AbstractSplit ponds are recently developed pond‐based aquaculture systems that allow intensification of catfish aquaculture. Successful industry‐wide adoption of newly developing technologies like split‐pond systems will depend upon their productivity and cost efficiencies. Costs and production performance of the following three split‐pond design scenarios were monitored in Arkansas and Mississippi: (1) research design developed at the Thad Cochran National Warmwater Aquaculture Center, Stoneville, Mississippi; (2) waterwheel design tested on commercial catfish ponds; and (3) screw‐pump design tested on commercial catfish ponds. An economic engineering approach using standard enterprise budget analysis was used to develop estimates of breakeven prices (BEPs) ($/kg) for producing foodsize hybrid catfish (♂Ictalurus furcatus × ♀Ictalurus punctatus) for each scenario. Estimates of BEPs of hybrid catfish raised in split ponds ranged from $1.72 to $2.05/kg. The cost of catfish production in split ponds was sensitive to yield, fish prices, and feed prices. Annual net cash flows from both commercial split‐pond systems were high and sufficient to make the investment profitable in the long run. Feed price, feed conversion ratio, and yield contributed the most to downside risk of split ponds.
Effects of E/Z Isomers and Coating Materials of Astaxanthin Products on the Pigmentation and Antioxidation of Rainbow Trout, Oncorhynchus mykiss
Authors: Zhao Xinxin , Hu Jing , Zhang Xiaoqing , Li Xiaoqin , Leng Xiangjun , Wu Shilin , Cheng Dong 
Published: April 2016

AbstractThe objective of this study was to compare the effects of four astaxanthin preparations with different ratio of E/Z (trans/cis) isomers and different coating materials on the pigmentation and antioxidation properties of rainbow trout. Five diets were designed as basal diet (without astaxanthin supplementation) and four astaxanthin diets (100 mg/kg diet) supplemented with four astaxanthin products, BASF (79% all‐E, gelatin coated), Wisdom‐B (85% all‐E, gelatin coated), Wisdom‐C (94% all‐E, carrageenan coated), and Wisdom‐D (94% all‐E, gelatin coated). After 4 wk feeding, the flesh astaxanthin content, redness, and yellowness of astaxanthin‐supplemented groups were higher than those of control group at the second and fourth week (P < 0.05). Among these astaxanthin‐supplemented groups, the Wisdom‐B group had the highest flesh redness and astaxanthin content. The astaxanthin‐supplemented groups also had the lower flesh frozen loss and malondialdehyde level than control group at the fourth week (P < 0.05). The results indicated that dietary 100 mg/kg astaxanthin could improve the flesh redness and antioxidation abilities of rainbow trout. The ration of E/Z isomers and properties of coating materials of astaxanthin preparations influenced the pigmentation and antioxidation properties, and Wisdom‐B had a better pigmentation effect on the flesh than other astaxanthin preparations.
Dietary variety and food group consumption in children consuming a cows' milk exclusion diet
Authors: Maslin Kate , Dean Tara , Arshad Syed Hasan , Venter Carina 
Published: April 2016

AbstractBackgroundDietary variety is defined as the number of different foods or food groups consumed over a given reference period, the consensus being that dietary variety and dietary quality are positively correlated. Recently there has been considerable interest in the association between infant dietary variety and atopic disease.MethodsThis was a cross‐sectional study of 8‐ to 27‐month‐old children from the Isle of Wight, UK, including two groups: a group of children consuming a cows' milk exclusion (CME) diet and a control group of children consuming an unrestricted diet. Parents completed a validated food frequency questionnaire, from which dietary variety and consumption of food groups were calculated. Growth measurements were recorded.ResultsA total of 126 participants of mean age 13.0 months were recruited. In addition to the expected differences in dairy and soya consumption, the CME group consumed sweet foods 1.6 times less frequently, non‐water drinks seven times less frequently (p < 0.05) and ready‐made baby foods 15 times more frequently (p < 0.01) than the control group. Overall dietary variety was significantly lower in the CME group (p < 0.01) as was variety of meat and sweet foods consumed. There was a greater concern with healthy eating in the CME group (p < 0.05).ConclusionsChildren consuming an exclusion diet for cows' milk allergy have an overall less varied diet, including a less varied consumption of meat and sweet foods. Efforts should be made to ensure exclusion diets are as varied as possible to optimize nutritional intake.
Stochastic Block Models for Multiplex Networks: An Application to a Multilevel Network of Researchers
Authors: Barbillon Pierre , Donnet Sophie , Lazega Emmanuel , Bar-Hen Avner 
Published: April 2016

Summary
Modelling relationships between individuals is a classical question in social sciences and clustering individuals according to the observed patterns of interactions allows us to uncover a latent structure in the data. The stochastic block model is a popular approach for grouping individuals with respect to their social comportment. When several relationships of various types can occur jointly between individuals, the data are represented by multiplex networks where more than one edge can exist between the nodes. We extend stochastic block models to multiplex networks to obtain a clustering based on more than one kind of relationship. We propose to estimate the parameters—such as the marginal probabilities of assignment to groups (blocks) and the matrix of probabilities of connections between groups—through a variational expectation–maximization procedure. Consistency of the estimates is studied. The number of groups is chosen by using the integrated completed likelihood criterion, which is a penalized likelihood criterion. Multiplex stochastic block models arise in many situations but our applied example is motivated by a network of French cancer researchers. The two possible links (edges) between researchers are a direct connection or a connection through their laboratories. Our results show strong interactions between these two kinds of connection and the groups that are obtained are discussed to emphasize the common features of researchers grouped together.
Extending the Archimedean Copula Methodology to Model Multivariate Survival Data Grouped in Clusters of Variable Size
Authors: Prenen Leen , Braekers Roel , Duchateau Luc 
Published: April 2016

SummaryFor the analysis of clustered survival data, two different types of model that take the association into account are commonly used: frailty models and copula models. Frailty models assume that, conditionally on a frailty term for each cluster, the hazard functions of individuals within that cluster are independent. These unknown frailty terms with their imposed distribution are used to express the association between the different individuals in a cluster. Copula models in contrast assume that the joint survival function of the individuals within a cluster is given by a copula function, evaluated in the marginal survival function of each individual. It is the copula function which describes the association between the lifetimes within a cluster. A major disadvantage of the present copula models over the frailty models is that the size of the different clusters must be small and equal to set up manageable estimation procedures for the different model parameters. We describe a copula model for clustered survival data where the clusters are allowed to be moderate to large and varying in size by considering the class of Archimedean copulas with completely monotone generator. We develop both one- and two-stage estimators for the copula parameters. Furthermore we show the consistency and asymptotic normality of these estimators. Finally, we perform a simulation study to investigate the finite sample properties of the estimators. We illustrate the method on a data set containing the time to first insemination in cows, with cows clustered in herds.
Oral health‐related quality of life in mild Alzheimer: patient versus caregiver perceptions
Authors: Campos Camila Heitor , Ribeiro Giselle Rodrigues , Rodrigues Garcia Renata Cunha Matheus 
Published: April 2016

ABSTRACTPurposeTo compare perceptions on oral health‐related quality of life (OHRQoL) between Alzheimer disease (AD) patients and their caregivers by using the Geriatric Oral Health Assessment Index (GOHAI). Correlation between GOHAI and prostheses quality was also performed.MethodsGOHAI was applied to 16 AD elders and their caregivers. GOHAI index was compared to objective measures of AD patients’ prostheses quality, rated by a researcher. Data were submitted to Wilcoxon signed rank and McNemar tests (α = 5%). Kappa correlations verified the concordance for GOHAI scores between AD patients and caregivers. Spearman's correlation was used to explore concordance between GOHAI scores and prostheses quality indices.ResultsTotal GOHAI scores from AD patients and caregivers were similar (P = 0.262). Overall Kappa was good (0.62). There were no correlations between GOHAI scores and prostheses quality.ConclusionAD patients assess and self‐report their OHRQoL similarly to their main caregiver.
Are Diuretics Underutilized in Dialysis Patients?
Authors: Trinh Emilie , Bargman Joanne M. 
Published: April 2016

AbstractWhile oral diuretics are commonly used in patients with chronic kidney disease for the management of volume and blood pressure, they are often discontinued upon initiation of dialysis. We suggest that diuretics are considerably underutilized in peritoneal dialysis and haemodialysis patients despite numerous potential benefits and few side effects. Moreover, when diuretics are used, optimal doses are not always prescribed. In peritoneal dialysis, the use of diuretics can improve volume status and minimize the need for higher glucose‐containing solutions. In patients on haemodialysis, diuretics can help lessen interdialytic weight gain, resulting in decreased ultrafiltration rates and fewer episodes of intradialytic hypotension. This paper will review the mechanism of action of diuretics in patients with renal insufficiency, quantify the risk of side effects and elaborate on the potential advantages of diuretic use in peritoneal dialysis and hemodialysis patients with residual kidney function.
Sedimentary characteristics of palaeolake deposits along the Indus River valley, Ladakh, Trans‐Himalaya: Implications for the depositional environment
Authors: Nag Debarati , Phartiyal Binita , Singh Dhruv Sen 
Published: April 2016

ABSTRACTThis study is an attempt to contribute to the data set of granulometric studies of sediments by measuring the sedimentary structure and texture, along with statistical parameters, of cold and arid lake systems. The palaeolake sequence along the River Indus on the western fringe of the Tibetan Plateau in Ladakh sector was selected in order to shed light on depositional environmental changes within the lake from post‐last glacial maximum to 5 ka. The River Indus was blocked by Lamayuru dam burst during the deglaciation, after the Last Glacial Maximum (LGM) and the subsequent increase in water level led to the formation of the Saspol–Khalsi palaeolake. This lake was ca 55 km in length, extending from Nimo to Khalsi, had a surface area of 370 km2 and was in existence until 5 ka. Two sections (Saspol and Khalsi) separated by an aerial distance of 35 km show a similar trend in sediment character due to their deposition in the same lake system. Grain‐size studies show a polymodal nature of sediments for both of the sections. However, sediments of the lower/downstream section (Khalsi) show a poorer degree of sorting, and coarser grain size and high energy depositional condition as compared with the sediments of Saspol section (positioned upstream) due to the location of the sections within the lake system. It was noted that, in high‐altitude arid regions, the sedimentological characteristics of large‐sized valley lakes may vary greatly, horizontally as well as vertically, owing to local stream input, inflow intensity from the catchment, outflow velocity of water channels, lithology and valley widths at the different sites.