bluuebunny/crossref_metadata_2025_split huggingface dataset:
Osteoporosis and ageing affects the migration of stem cells and this is ameliorated by transfection with CXCR4
Authors: Sanghani-Kerai A. , Coathup M. , Samazideh S. , Kalia P. , Silvio L. Di , Idowu B. , Blunn G. 
Published: June 2017

Objectives Cellular movement and relocalisation are important for many physiologic properties. Local mesenchymal stem cells (MSCs) from injured tissues and circulating MSCs aid in fracture healing. Cytokines and chemokines such as Stromal cell-derived factor 1(SDF-1) and its receptor chemokine receptor type 4 (CXCR4) play important roles in maintaining mobilisation, trafficking and homing of stem cells from bone marrow to the site of injury. We investigated the differences in migration of MSCs from the femurs of young, adult and ovariectomised (OVX) rats and the effect of CXCR4 over-expression on their migration. Methods MSCs from young, adult and OVX rats were put in a Boyden chamber to establish their migration towards SDF-1. This was compared with MSCs transfected with CXCR4, as well as MSCs differentiated to osteoblasts. Results MSCs from OVX rats migrate significantly (p < 0.05) less towards SDF-1 (9%, sd 5%) compared with MSCs from adult (15%, sd 3%) and young rats (25%, sd 4%). Cells transfected with CXCR4 migrated significantly more towards SDF-1 compared with non-transfected cells, irrespective of whether these cells were from OVX (26.5%, sd 4%), young (47%, sd 17%) or adult (21%, sd 4%) rats. Transfected MSCs differentiated to osteoblasts express CXCR4 but do not migrate towards SDF-1. Conclusions MSC migration is impaired by age and osteoporosis in rats, and this may be associated with a significant reduction in bone formation in osteoporotic patients. The migration of stem cells can be ameliorated by upregulating CXCR4 levels which could possibly enhance fracture healing in osteoporotic patients. Cite this article: A. Sanghani-Kerai, M. Coathup, S. Samazideh, P. Kalia, L. Di Silvio, B. Idowu, G. Blunn. Osteoporosis and ageing affects the migration of stem cells and this is ameliorated by transfection with CXCR4. Bone Joint Res 2017;6:–365. DOI: 10.1302/2046-3758.66.BJR-2016-0259.R1.
Vorstadt, Sport und jüdische Identitäten
Authors: Colpan Sema , Marschik Matthias 
Published: June 2017

AbstractResearch on Jewish life in Vienna prior to the Holocaust understandably focuses on places, where it predominantly took place: the Leopoldstadt and the city centre. This view fails to consider the suburb, an area that reflects spatial aspects of Jewish life and does not evoke the connotations typically associated with being Jewish but is instructive as it regards questions of »Jewish difference«. Based on the biographies of two Jewish sports officials, the article shows that (Jewish) difference was defined primarily by parameters of space which manifest as »Bodenständigkeit« (being native): In actual fact, at least in the field of popular culture, ascriptions to a non-Jewish suburb were more powerful than the Jewishness of the officials: In self-perceptions as well as in external ascriptions the meanings of Jewishness were informed by suburban affiliations.
Bouché’s star of Bethlehem, Ornithogalum boucheanum (Kunth) Asch. (Hyacinthaceae), a new species in flora of Croatia
Authors: Purger Dragica , Kovačić Sanja , Csiky János 
Published: June 2017

AbstractPopulations of Bouché’s star of Bethlehem (Ornithogalum boucheanum(Kunth) Asch., fam. Hyacinthaceae) were recorded on Bansko Hill (Baranja, Croatia) in 2007. Since this species has not been previously confirmed in Croatia, it should be treated as a new taxon in the country and included in the Flora Croatica Database. In this paper we present a short morphological description ofO. boucheanumand diagnostic morphological characters for differentiation from the relatedO. nutansL. We suggestedO. boucheanumbe evaluated as a critically endangered (CR) species of the Croatian flora, considering the small number of individuals and the small extension of its population. The recording of its populations on the edge of the loess cliff in Bansko Hill a part of which belongs to the Important Plant Area and Natura 2000, confirms the significance of this unique habitat in preserving rare and endangered plants.
From Text Comprehension to Creative Writing from the Aspect of Cognitive Linguistics
Authors: Kováčová Zuzana 
Published: June 2017

Abstract
Text comprehension is understood as a social and cultural phenomenon in which it is possible to identify the developmental phases, that is ontogenesis, from the aspect of communicating entity. The age-receptive value, as well as the age-receptive variability of text, is reflected in the texts for children. Works of folk or authorial provenance anticipate the mental dispositions of a child subject. Developing the understanding by children is resulting from formal and content criteria. Understanding – like speech – grows. The supreme level of text comprehension is the improvisation of larger narrative formations: Compared with the primary contact with the text in the form of rhymes, the form is released and the epic breadth of expression increases. The child as authorial subject produces a text that is characterized by such variability of expression values which is contained in the child´s current mental model reached through conventions and receptive experience. The study will demonstrate the expressive value of text using examples of creative writing of children. Methodologically, it relies on the semantic communication model of text and the expressive value of text.
Growing up Dalit in Bengal: Conversation with Manohar Mouli Biswas
Authors: Bhaumik Mahuya , Sarangi Jaydeep 
Published: June 2017

Abstract
This is an interview of Manohar Mouli Biswas, Bangla Dalit activist and writer, where he expresses his views about the identity of Dalit people and the historiography of caste in India. He further speaks about the uniqueness of Bangla Dalit literature, its similarities with Dalit writings in other Indian regional languages and the position of Dalit women writers. He is candid enough to speak about certain autobiographical elements that provided him with the impetus to be a Dalit writer. He further speaks about Dalit drama and its performances which is a marker of its acceptance amongst the viewers. He emphasises on the role of translation of Dalit literature to generate awareness among the larger reading public towards Dalit literature.
Domain Decomposition Methods for Recovering Robin Coefficients in Elliptic and Parabolic Systems
Authors: Jiang Daijun , Feng Hui 
Published: June 2017

Abstract
We shall derive and propose several efficient domain decomposition methods for solving the nonlinear
inverse problem of identifying the Robin coefficients in elliptic and parabolic systems.
The highly ill-posed inverse problems are transformed into output
least-squares nonlinear and non-convex minimizations with classical Tikhonov regularization.
The Levenberg–Marquardt method is
applied to transform the non-convex minimizations into convex minimizations,
which will be solved by several efficient domain decomposition methods.
The methods are completely local and the local minimizers
have explicit expressions within the subdomains.
Several numerical experiments are presented to show the accuracy
and efficiency of the methods; in particular, the convergence seems nearly optimal in the sense
that the iteration number of the methods is nearly independent of
mesh sizes.
Incorporation of Ag Nanoparticles Into Micelles. Stability Studies of Self-Organized Nanoparticlesmicelles Structures
Authors: Siejak Przemysław , Polewski Krzysztof 
Published: June 2017

Abstract
In this paper we present the results of measured physical parameters of self-organized structures consisting of hydrophobic functionalized silver nanoparticles and amphiphilic molecules capable of micelles formation. Those systems may be considered as simple models for transfer of nanoparticles through the biological membrane. Three different surfactants were used: negatively charged sodium dodecyl sulphite, SDS, neutral Triton X-100 and positively charged tetredodecyltrimethyl ammonium bromide, TTABr. We have found that hydrophobic functionalized Ag nanoparticles are encapsulated in neutral Triton X-100 micelles with a diameter of 10 nm without significant change in the size of the micelles. The efficiency of encapsulation of Ag by SDS micelles is lower compared to Triron X-100 and no incorporation of Ag nanoparticles into TTABr occurs. Obtained results indicate that in aqueous environment ionic properties of molecules creating micelles and concentration ratios between components determine the efficiency and kinetics of two competitive processes association or aggregation of nanoparticles and encapsulation of Ag nanoparticles within micelles.
Effect of Time and Concentration on Mortality of the Cigarette Beetle, Lasioderma serricorne (F.), Fumigated With Phosphine
Authors: Fukazawa Naoto , Takahashi Ryota 
Published: June 2017

Summary
The efficacy of a fumigant is determined by the gas concentration and exposure time. Typically, the gas concentration and exposure time are equally important in fumigation efficacy and their relationship is expressed as Ct = k, where C is the concentration, t is the time and k is a constant (Haber’s rule). However, deviation from Haber’s rule, i.e., the relative importance of time over concentration, has been reported for several stored-product pests, and a modified form (Cn t = k) is used to express the relationship between C and t. This study aimed to determine if this modified form could be applied to phosphine fumigation of the cigarette beetle, Lasioderma serricorne (F.). Adult beetles from six cultures with different phosphine-resistance levels were exposed to phosphine (1–2000 ppm) at 25 °C for either 24, 72, 120, or 168 h, and the phosphine concentration necessary to achieve 50% lethality (LC50) was calculated. The phosphine concentration (C) and the exposure time (t) relationship at the LC50 for all six cultures were determined by regression analyses. The equation Cn t = k was a good fit for all the cultures tested, irrespective of phosphine resistance. The results showed the exponent n was less than 1 (0.51 ≤ n ≤ 0.71, coefficient of determination 0.90–0.99), suggesting that time is more important than concentration in toxicity expression of phosphine against L. serricorne. Therefore, extending the exposure time rather than increasing the concentration should be emphasized to manage the future threat of resistance problems with phosphine.
2016 Excavations at Poggio Civitate and Vescovado di Murlo
Authors: Tuck Anthony , Kansa Sarah , Kreindler Kate , O’Donoghue Eoin 
Published: June 2017

AbstractThis report details excavations carried at at the site of Poggio Civitate and Vescovado di Murlo during the 2016 excavation campaign. Work both clarified aspects of the form and date of a monumental palazzo originally revealed during the previous season’s excavation and also clarified the architectural details of a small, later, potentially domestic structure located within the earlier building’s confines. Excavation at the associated site of Vescovado di Murlo revealed the presence of a significant defensive work and associated moat, apparently destroyed in the early years of the 4th century BCE.
Ecology and biology of birds in the Białowieża Forest: a 40-year perspective
Authors: Czeszczewik Dorota , Walankiewicz Wiesław 
Published: June 2017

AbstractThe aim of this study was to review the most important results from the last 40 years of intense ornithological research conducted in the Białowieża Forest. Furthermore, we discuss the threats that may destroy the unique ecology and characteristics of this forest.Studying the avifauna of the Białowieża Forest provides us with a good general knowledge about natural ecological conditions and relationships, which prevailed in temperate European forests in the past. The avifauna of the Białowieża Forest is characterized by features associated with primeval habitats such as the stability of communities over time, high species richness, relatively low densities, high proportion of hole-nesting birds, very high predation pressure and weak, insignificant competition interactions. This emphasizes the importance of predation, excess of nesting sites for cavity nesting birds, high abundance of food, especially for insectivorous species and fluctuation of bird population size due to rodent outbreaks (pulsed resources). The most severe threats for the avifauna of the Białowieża Forest are: rejuvenation of tree stands, removal of dead wood, fragmentation of old-growth stands, change of tree stand composition (reducing the proportion of some tree species).In order to expand our ecological knowledge about birds, we should keep the Białowieża Forest fully protected for years to come. The main priority should be the maintenance of natural processes changing the forest’s species composition.
Managing bark beetle outbreaks (Ips typographus, Dendroctonus spp.) in conservation areas in the 21st century
Authors: Kulakowski Dominik 
Published: June 2017

AbstractForests in Europe and North America are being affected by large and severe outbreaks of bark beetles, which have caused widespread concern about forest health and have led to proposals for tree removal in affected or susceptible forests. Any such intervention, as well as broader decisions of whether any active interventions are appropriate, should be based on the best scientific data. This is true for all forests, including those whose purposes include timber production, watershed protection, biogeochemical function and recreation, and especially protected and conservation areas as the latter often provide particularly unique and important cultural, social, scientific and other ecosystem services. Here, I summarize peer-reviewed literature on the effects of bark beetle outbreaks and on silvicultural treatments aimed at mitigating beetle-induced tree mortality. From an objective scientific perspective, beetle outbreaks do not destroy forests. Instead, in many cases they play an important role in promoting wildlife, biodiversity and other ecological services. The best available data indicate that logging in conservation areas is unlikely to stop ongoing bark beetle outbreaks and instead may be more ecologically detrimental to the forests than the outbreaks themselves. If the purpose of a forest is timber production, then logging is desirable and can be planned based on appropriate analyses of timber yield and economic profit. However, in areas in which conservation is the determined goal, it is recommended that cutting trees be limited to removing hazards, such as trees that might fall in areas of high human activity in order to limit property damage and personal injury. Based on extensive research in Europe and North America, logging beetle-affected forests is inconsistent with most conservation goals.
Determination of uronic acids and neutral carbohydrates in pulp and biomass by hydrolysis, reductive amination and HPAEC-UV
Authors: Lorenz Dominic , Janzon Ron , Saake Bodo 
Published: June 2017

AbstractThe exact quantification of all carbohydrate constituents in wood and pulp is a challenge because of the various glycosidic linkages of the polysaccharides with different stabilities. The individual detector responses for the compounds in the hydrolysates additionally complicate the quantification as pure standards for 4-O-methyl-α-D-glucuronic acid (meGlcA) and related oligosaccharides are not commercially available for calibration. In the present paper, a new analytical procedure is presented, based on the reductive amination of the carbohydrates obtained via acidic and enzymatic hydrolysis of the polysaccharides before quantification by means of high performance anion exchange chromatography (HPAEC) and UV-detection. This approach was suitable for the analysis of neutral carbohydrates and uronic acids obtained via enzymatic hydrolysis from bleached pulps. In the case of unbleached pulps, the enzymatic hydrolysis was not complete and unhydrolyzed nano-scaled and micro-scaled particles remained in the hydrolysates as detected by dynamic light scattering (DLS) measurements. The new HPAEC-UV methodology was also applied to kraft pulps and a sulfite pulp; six different kinds of wood as well as wheat straw and bagasse. All relevant monosaccharides and the dimer of meGlcA and xylose could be detected in the hydrolysates. Accordingly, significantly higher yields of meGlcA were found compared to literature data.
Cloud-Based Application for Smart Grid Simulation
Authors: Tar Szabolcs , Fodor Attila 
Published: June 2017

Abstract
This study provides an overview of the content of an R&D project for increasing the efficiency of smart grids to analyse the energy market, consumption, generation, and renewable energy usage. The new energy participants, for example decentralized generation, dynamic consumption, and weather-dependent power plants, are facing challenges. This project offers solutions to these challenges: modelling of distribution networks, forecasts of renewable energy sources distributed generation (RES-DG), micro-grid management and responses to demand in new, complex solutions. A hardware device is being developed for smart grids and security modules to enhance IT security.
Effect of Surface Fe-Sn Intermetallics on Oxide Films Formation of Stainless Steel in High Temperature Water
Authors: Zhao Yan , Guan Jianjun , Liu Feng , Cheng Congqian , Zhao Jie 
Published: June 2017

AbstractThe oxidation of stainless steel with Fe-Sn intermetallics adhesion in 300 °C water was studied by analyzing the morphologies and phase structures of surface oxide films. The oxidation behavior of stainless steel was discussed in order to illustrate the effect of Fe-Sn intermetallics on the oxidation characteristic. Larger size of faceted spinel and small size of SnO2 particles are observed on the samples with Fe-Sn intermetallics adhesion, whereas smaller faceted hematite and spinel grow on the samples without Fe-Sn intermetallics adherence. The surface intermetallics aggravates the spalling of oxide particles and decreases the corrosion resistance of stainless steel. Such deterioration is attributed to the loose microstructure characteristic and the poor corrosion resistance of SnO2 particles formed in high temperature water.
Performing rebelliousness: Dutch political humor in the 1780s
Authors: Nieuwenhuis Ivo 
Published: June 2017

AbstractThis article takes the notion of rebelliousness as the starting point for an analysis of eighteenth-century Dutch political humor. In several recent publications from humor scholars, the rebellious image of political humor in today’s world is questioned. This skepticism towards the idea of humor as a form of rebellion is connected to four sources of political humor that were published as part of the conflict between the reformist Patriots and the conservative Orangists, that took place in the Dutch Republic during the 1780s. It is shown that, comparable to the situation in contemporary political humor, the rebellious outlook of these sources is to a large extent a matter of rhetoric and convention. Their crossing of social and cultural boundaries and their attacks on the powers that be are part of a long cultural tradition, of which the actual social impact is doubtful. Also, the humor used in these sources contains obvious disciplinary tendencies, that emasculate their rebellious potential in yet another way. The new insights regarding political humor of the past that are thus produced prove the scholarly relevance of connecting theoretical perspectives based on the study of contemporary humor to historical cases of humor.
Original Article. The Clinical Effects Study of Hepatic Failure by Intraperitoneal Injection of Antibiotics, Intravenous Injection of Terlipressin, and Combined Therapy of Coloclysis and Plasma Exchange
Authors: Li Hui , Wang Ya-ling , Tian De-ying 
Published: June 2017

Abstract
Objective To observe the therapeutic effects of intraperitoneal injection of antibiotics, intravenous injection of terlipressin, and combined treatment of coloclysis and plasma exchange on hepatic failure(HF), the subjects included 494 inpatient cases of hepatic failure who were treated in Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China from 1997 to 2008.
Methods The patients that met the inclusion criteria were divided into intraperitoneal antibiotic injection group, intravenous terlipressin injection group, coloclysis group, plasma exchange group, combination group of coloclysis and plasma exchange in terms of treatment given and a control group was set up for each of the treatment group. In the intraperitoneal injection group, the prognosis and changes in clinical manifestations were observed in HF patients complicated with spontaneous peritonitis (SBP). In terlipressin injection group,HF patients complicated with hepatorenal syndrome (HRS) were observed for prognosis and changes in serum creatinine. In the combination group, the improvement in serum total bilirubin and prothrombin activity were observed.
Results Two weeks after intraperitoneal injection of antibiotics, the ease ratios of abdominal pain, pressure pain and rebound tenderness were 87.64%, 82.02% and 82.02% in the intraperitoneal injection group, respectively and the volume of ascites obviously decreased in 69 patients (77.53%). The survival rate in intraperitoneal injection group was significantly higher than in control group (P ＝ 0.004). Four to eight days after the intravenous injection of terlipressin, the survival rate and the rate of serum creatinine decline of the treatment group were significantly higher than those in the control group (P ＝ 0.003, P ＝ 0.000). After 4 weeks of treatment, the ratio of clinical symptoms improvement (acratia, anorexia, abdominal distension, constipation) in coloclysis group were 60.27%, 57.53%, 91.78% and 94.52%, in plasma exchange group were 71.83%, 69.44%, 75% and 72.22%, and in combination group were 82.14%, 79.46%, 92.85% and 95.54%. The serum total bilirubin was decreased and the prothrombin activity increased and the differences were statistically significant as compared with control group (P ＝ 0.000).
Conclusions The intraperitoneal injection of antibiotics, intravenous injection of terlipressin and combined treatment of coloclysis and plasma exchange were all effective for the treatment of HF and its complications.
Factors Associated with Death Due to 2009 Influenza A (H1N1) Virus Infection and Acute Respiratory Distress Syndrome in Beijing, 2009 - 2011
Authors: Zhang Jin-qian , Zhang Li-cheng , Ren Na , Zhang Ming , Guo Li-min , Li Xing-wang , Cheng Jun 
Published: June 2017

Abstract
Objective Patients with H1N1 virus infection were hospitalized and quarantined, and some of them developed into acute respiratory failure, and were transfered to the medical intensive care unit of Beijing Ditan Hospital, Capital Medical University in Beijing, China.
Methods The clinical features and preliminary epidemiologic findings among 30 patients with confirmed H1N1 virus infection who developed into acute respiratory failure for ventilatory support were investigated.
Results A total of 30 patients (37.43 ± 18.80 years old) with 2009 influenza A (H1N1) related acute respiratory distress syndrome (ARDS) received treatment with mechanical ventilation, 15 cases of whom were male and 17 cases died of ARDS. Fatal cases were significantly associated with an APACHE Ⅱ score (P = 0.016), but not with PaO2/FIO2 (P = 0.912) and chest radiograph (P = 0.333). The most common complication was acute renal failure (n = 9). Five patients received extracorporeal membrane oxygenation (ECMO), 3 of whom died and the others survived. The major causes of death were multiple organ dysfunction syndrome (MODS) (39%), intractable respiratory failure (27%) and sepsis (20%).
Conclusions Most patients with respiratory failure due to influenza A (H1N1) virus infection were young, with a high mortality, particularly associated with APACHE ∥ score, secondary infection of lung or type 2 diabetes mellitus.