bluuebunny/crossref_metadata_2025_split huggingface dataset:
Purification, crystallization and initial crystallographic analysis of the α-catenin homologue HMP-1 fromCaenorhabditis elegans
Authors: Kang Hyunook , Bang Injin , Weis William I. , Choi Hee-Jung 
Published: February 2016

Adherens junctions transmit mechanical force between cells. In these junctions, β-catenin binds to cadherins and to the N-terminal domain of α-catenin, which in turn binds to actin filamentsviaits C-terminal domain. The middle (M) domain of α-catenin plays an important role in responding to mechanical tension. The nematodeCaenorhabditis eleganscontains α- and β-catenin homologues called HMP-1 and HMP-2, respectively, but HMP-1 behaves differently from its mammalian homologue. Thus, structural and biochemical studies of HMP-1 have been initiated to understand the mechanism of HMP-1 and the evolution of α-catenin. The N-terminal domain of HMP-1 in complex with the minimal HMP-1-binding region of HMP-2 was purified and crystallized. These crystals diffracted to 1.6 Å resolution and belonged to space groupP3121, with unit-cell parametersa=b= 57.1,c= 155.4 Å. The M domain of HMP-1 was also purified and crystallized. The M-domain crystals diffracted to 2.4 Å resolution and belonged to space groupP212121, with unit-cell parametersa = 72.8,b= 81.5,c = 151.4 Å. Diffraction data were collected and processed from each crystal, and the structures were solved by molecular replacement.
Understanding recovery: the perspective of substance misusing offenders
Authors: Senker Sarah , Green Gill 
Published: February 2016

Purpose
– The purpose of this paper is to critically regard the concept of recovery from the perspective of substance misusing offenders. It intended to understand how these individuals came to define recovery by asking “what does recovery mean to you?”

Design/methodology/approach
– In total, 35 semi-structured interviews were undertaken with individuals with a history of heroin and crack cocaine use as well as convictions for a range of offences. Interviews took place in both prison and community settings, reflecting a spectrum of experience.

Findings
– Whilst the constellation of recovery varied, it was at times made up of the same “stars” – and some re-occurring themes emerged; recovery was transient, fragile and unpredictable, it was ongoing, lacking a definitive end, it was more than abstinence and often involved a total psychological overhaul, recovery was about reintegrating with society and feeling “normal”.

Practical implications
– Practitioners and services need to value the individual interpretations of recovery rather than being prescriptive around what it “should” look like. The components of recovery that were raised by participants permit specific recommendations for practice to be made.

Originality/value
– This study sought the perspectives of those actually affected by and experiencing drug treatment in the Criminal Justice System. It allowed participants to tell their story without preconceived ideas or hypotheses, putting their voice at the centre of the stage. The study uses feedback from the ground to make informed recommendations for practice.
Improving access and managing healthcare demand with walk-in clinic
Authors: Kork Anna-Aurora , Vakkuri Jarmo 
Published: February 2016

Purpose
– Poor access to healthcare and increasing demand for services represent a management dilemma how to balance between needs and costs. Scrutinising the concept of demand management and using a case study from Finnish primary care, the purpose of this paper is to examine the complexities of managing demand for health services.

Design/methodology/approach
– Convenience has explained the popularity of walk-in clinics (WIC), making it an attractive demand management tool. By analysing the quantitative service utilisation data of frequent attenders at WIC, the paper exemplifies what enhanced access to care means for demand management of public welfare services.

Findings
– High user rates and satisfaction indicate demand for this type of service; however, the establishment of WIC provided supplementary care for the high users of health services, most suffering chronic diseases.

Research limitations/implications
– Better understanding of the structure of service demand is needed in order to develop a more coordinated service system and to manage demand for public welfare services.

Practical implications
– The study demonstrates the importance of identifying service utilisation patterns in managing demand. Instead of single solutions, a wider system-level perspective is essential.

Originality/value
– Managing demand and facilitating access are core primary care attributes but there is little evidence about the impact of demand management strategies. The paper ties together important healthcare management issues: how to control demand and improve the access? Moreover, few studies have examined the frequent attendance at WIC. This paper presents a practical illustration of demand management tool and indicates some demand management problems to be considered in healthcare management.
Are online communities on par with experts in the evaluation of new movies? Evidence from the Fandango community
Authors: Ponnamma Divakaran Pradeep Kumar , Nørskov Sladjana 
Published: February 2016

Purpose– The purpose of this paper is to investigate two questions. First, are movie-based online community evaluations (CE) on par with film expert evaluations of new movies? Second, which group makes more reliable and accurate predictions of movie box office revenues: film reviewers or an online community?Design/methodology/approach– Data were collected from a movie-based online community Fandango for a 16-month period and included all movies released during this time (373 movies). The authors compared film reviewers’ evaluations with the online CE during the first eight weeks of the movie’s release.Findings– The study finds that community members evaluate movies differently than film reviewers. The results also reveal that CE have more predictive power than film reviewers’ evaluations, especially during the opening week of a movie.Research limitations/implications– The investigated online community is based in the USA, hence the findings are limited to this geographic context.Practical implications– The main implication is that film studios and movie-goers can rely more on CE than film reviewers’ evaluation for decision making. Online CE can help film studios in negotiating with distributors, theatre owners for the number of screens. Also, community reviews rather than film reviewers’ reviews are looked upon by future movie-goers for movie choice decisions.Originality/value– The study makes an original contribution to the motion picture performance research as well as to the growing research on online consumer communities by demonstrating the predictive potential of online communities with regards to evaluations of new movies.
Towards a better understanding of system analysts’ tacit knowledge
Authors: Prasarnphanich Pattarawan , Janz Brian D. , Patel Jignya 
Published: February 2016

Purpose– The purpose of this paper is to elicit tacit knowledge exhibited in expert information system (IS) professionals in a form that can be shared with others; and to develop categorical framework suggesting key content areas of tacit knowledge in the requirements analysis domain.Design/methodology/approach– Requirements analysis is selected as the main focus of this study due to the importance of this phase to the success of IS development and the nature of requirements analysis tasks requiring extensive amount of tacit knowledge. The authors used the “storytelling” approach, a semi-structured interview technique for knowledge elicitation.Findings– The study resulted in 132 knowledge items using a qualitative method and categorized them into 14 categories using cluster analysis. The study found that experienced, successful analysts see systems analysis in behavioral, managerial, and political terms and focus heavily on interpersonal, project management, and organizational issues.Research limitations/implications– The limitations in the research sample, or in the recollection capability of the research subjects could compromise the comprehensiveness of the tacit knowledge in the requirements analysis domain; however, the elicited knowledge at least represents important dimensions one might reasonably find in this domain.Originality/value– Very little research has attempted to capture this tacit dimension of system analysts’ knowledge. Thus, capturing and transferring the tacit knowledge from experts should help in the evolution of novice to expert system analysts thereby improving both their effectiveness and the quality of the information systems developed.
Enhancing perceived enjoyment in social games through social and gaming factors
Authors: Chen Aihui , Lu Yaobin , Wang Bin 
Published: February 2016

Purpose
– Residing on social networking platforms, social games have unique characteristics distinguishing them from other digital games or online games. The purpose of this paper is to explore both social and gaming factors of social games and investigate their roles on enhancing perceived enjoyment. The authors also examine the relationships between perceived enjoyment, subject norm, perceived critical mass, intention to play, and actual behavior.

Design/methodology/approach
– This paper develops a research model including nine hypotheses. Using a survey questionnaire, empirical data were collected from 169 actual social game players. Structured equation modeling was used to test the proposed research models.

Findings
– Social identification, social interaction, and diversion significantly influence perceived enjoyment. Perceived enjoyment significantly influences the intention to play, which in turn significantly influences the actual behavior. Moreover, subject norm and perceived critical mass play different roles in determining the intention to play and the actual behavior.

Practical implications
– The results of this study provide social game practitioners with a set of rich insights into guidelines on designing specific social and gaming characteristics to improve users’ perceived enjoyment and actual playing behavior.

Originality/value
– Through analyzing characteristics of social games, The authors emphasize the difference between social games and other online games or computer games and recognize the enhancing role of social and gaming factors on perceived enjoyment. Findings of this study contribute to the literature on social games.
Examining information systems infusion from a user commitment perspective
Authors: Kim Hee-Woong , Chan Hock Chuan , Gupta Sumeet 
Published: February 2016

Purpose– The purpose of this paper is to : first, examine information systems (IS) infusion from a user commitment perspective, and second, examine the formation of user commitment toward the use of IS in terms of job design.Design/methodology/approach– This study adopts a survey approach with structural equation modeling to test the developed research model and hypotheses.Findings– A survey of 236 enterprise system users shows that user commitment has a positive effect on IS infusion. User commitment, in turn, is influenced by task technology fit, technology self-efficacy, and task autonomy. Further mediation and direct effects to IS infusion are explored.Research limitations/implications– This study offers implications for research, such as explaining a driver of IS infusion; and extending commitment theory by finding antecedents of user commitment.Practical/implications– The results of this study offer suggestions to management on how to improve IS infusion in terms of user commitment and, consequently, how to develop user commitment based on the socio-technical system (STS) design.Social/implications– The study highlights the critical impact of technology autonomy on IS infusion. An individual user’s authority in using and regulating the system is required for IS infusion.Originality/value– This study has proposed a theoretical model of IS infusion based on commitment and socio-technical job design factors.
Design-based mathematics workshops
Authors: Xiao Lu , Namukasa Immaculate , Zhang Yibing 
Published: February 2016

Purpose
– The purpose of this paper is to present a workshop model for engaging children and parents in mathematics activities in public libraries or other informal education settings.

Design/methodology/approach
– This paper explores a workshop model for helping the school-aged children learn mathematics outside the school. The model includes five workshop sessions and designs the parent’s role in the mathematics activities. Each workshop session has both a mathematics task activity and a user interface design activity. The model was implemented in a major Canadian city and a major Chinese city over a period of one month. This paper presents the workshop attendees’ experiences and their feedback on the workshop design. It also presents several suggestions on the design of such workshops.

Findings
– The parents acknowledged that they learned about how mathematics is currently taught in schools and appreciated the opportunities to interact with their children in the workshops. The children participated in the workshops actively and enjoyed the design sessions the most. The potential of using design activities to help children learn mathematics concepts is recognized.

Research limitations/implications
– The findings suggest that future workshops should provide a structure to the parents’ engagement in design activities, offer one design project that spans several design sessions and set aside time for families to mingle and share experiences with each other. A big limitation of this paper is the small sample size – 12 families participated in the workshops on each site. Although the paper offered rich data about the participants’ experiences, a larger sample would have made the findings more generalizable and conclusive.

Practical implications
– Computer technologies such as iPad and tablets are increasingly common as public library resources; yet the integration of these technologies into library programs is falling behind. This paper offers one example of how such integration can bring benefits to the patrons, encouraging more considerations to be put on this aspect in library practice.

Originality/value
– Although many programs are offered in public libraries that facilitate children to learn mathematics concepts, very less research has been reported on the design of these programs. In addition, the existing programs have not considered the inclusion of parent–child design activities for mathematics learning engagement. This paper reports an empirical study that addresses these research gaps. The encouraging results call for more investigations on this workshop model.
Omeka.net as a librarian-led digital humanities meeting place
Authors: Rath Linda 
Published: February 2016

Purpose
– This case study aims to evaluate Omeka.net, the hosted Web publishing exhibit tool, as a low-cost and technology-friendly platform encouraging dynamic academic and non-academic communities to collaborate, explore and contribute to a genre film festival resource.

Design/methodology/approach
– A literature review established six variables to assess Omeka.net as a viable platform for libraries seeking to administer a resource-focused website adhering to information standards with limited budgets, training and technical or institutional support. The variables identified were cost; website management; content building and management; communities, engagement and collaboration; exploration and knowledge building; and website support.

Findings
– Omeka.net supports many activities with notable functions for website administration; collection building; media formats; collaboration; metadata; social media; user contributions; technical support; and the creation of simple, custom pages. While templates for page layouts offer a surprising amount of choices, some options are limited. Currently, interactive and exploratory items cannot be embedded into website pages.

Originality/value
– This paper discusses Omeka.net, the hosted version of the exhibit tool offered by Omeka, as a platform to encourage cross-sector collaboration for digital humanities projects, addressing a gap in the literature which focuses on Omeka.org, the open-source software version installed by libraries with access to servers and technical staff.
Disparités salariales au Pérou: les raisons de la pénalisation particulière des femmes autochtones
Authors: KOLEV Alexandre , SUÁREZ ROBLES Pablo 
Published: February 2016

RésuméEn Amérique latine, les inégalités entre groupes ethniques au travail inquiètent. A partir de données de l'Enquête nationale auprès des ménages, les auteurs analysent les disparités salariales entre groupes ethniques au Pérou, par sexe, sur la période 2005–2011. Ils concluent que l'écart salarial lié à l'origine ethnique est plus important que l'écart lié au sexe et que les femmes autochtones sont doublement pénalisées. Ils distinguent la part inexpliquée de l'écart salarial entre groupes ethniques (estimation haute de la discrimination) et sa part expliquée (décomposée entre effets des caractéristiques individuelles, du type d'emploi et du lieu de résidence). Ils préconisent en conséquence une action ciblée.
La discrimination salariale liée au sexe en Jordanie: les bonnes intentions ne suffisent pas
Authors: ALFARHAN Usamah F. 
Published: February 2016

RésuméLa Jordanie, qui est partie aux principaux instruments internationaux interdisant la discrimination à l'égard des femmes, présente toujours un écart salarial important entre les sexes. L'auteur décompose cet écart à partir de données de l'Enquête sur le revenu et les dépenses des ménages, en tenant compte des décisions d'activité des deux sexes. Il montre qu'il peut être expliqué dans sa totalité par les différences dans les coefficients estimés pour les hommes et les femmes, qu'il est généré à l'embauche, qu'il tend à diminuer par la suite et que l'activité féminine réduite améliore statistiquement le salaire relatif des femmes.
An ISO‐Protein Model Food System for Evaluating Food Texture Effects
Authors: Campbell Caroline L. , Daubert Christopher R. , Drake Maryanne , Foegeding E. Allen 
Published: February 2016

AbstractPerceptions of food quality, acceptability and satiety are often driven by food texture. It is hypothesized that food texture alters satiety by adjusting eating rate and enjoyment; however, few studies have evaluated wide ranges of food textures with standardized nutritional compositions. The goal of this study was to formulate and characterize a set of isocaloric, macronutrient‐matched model foods with varying textures. Six distinct food textures were produced by varying the extent and type of aggregation of 11% whey protein isolate solutions. Textures were grouped into fluid‐like (fluid, thin and thick semisolids) and solid‐like (three soft solid gels) based on rheological and sensory properties. Increasing sample mechanical stiffness coincided with increasing cohesiveness in fluid‐like textures and decreasing cohesiveness in solid textures; total oral manipulations increased with increasing stiffness. Trends in sensory cohesiveness reflected that solid textures are fractured with the molars while fluid‐like textures are manipulated by tongue and jaw movements. These model foods demonstrated properties in the range of commercial food products. They are applicable to investigating structural mechanisms responsible for texture and satiety. A scheme was developed that outlines structural breakdown and coinciding perception of textural properties during oral processing.Practical ApplicationsUnderstanding the multidisciplinary relationships among food structure, texture, sensory perception, satiety and nutrient availability are fundamental in the formulation of healthy and enjoyable food products. However, the selection of products to evaluate the role of food structure upon texture and health is often difficult due to variations in macronutrients, total calories, and sample volume. This research provides a nutritionally standardized model food system that spans a textural spectrum of fluids, semisolids, and soft solids. The basic model foods presented here can be used to establish fundamental relationships between food structure and physiological outcomes. Additionally, these model foods can easily be reformulated to represent more complex structures (e.g., mixed gels, emulsions) or to evaluate the effects of added flavor or color.
Assessment of hemostatic changes in a model of acute hemorrhage in dogs
Authors: Lynch Alex M. , deLaforcade Armelle M. , Meola Dawn , Shih Andre , Bandt Carsten , Guerrero Natalia Henao , Riccó Carolina 
Published: February 2016

AbstractObjectiveTo evaluate hemostatic changes following experimental acute hemorrhage in dogs using traditional coagulation tests (eg, platelet count, prothrombin time [PT], and activated partial thromboplastin time [aPTT]), kaolin‐activated thromboelastography (TEG), and whole blood multiple electrode impedance platelet aggregometry.DesignProspective study.SettingResearch laboratory.AnimalsFive Beagles.InterventionsDogs were anesthetized prior to obtaining blood samples for baseline PCV, total plasma protein (TPP), arterial blood‐gas, platelet count, PT, aPTT, TEG, fibrinogen, and aggregometry. Blood was obtained at 4 additional time points, following 20% blood volume loss, 40% blood volume loss, 60 minutes of sustained hypotension, and after autologous blood transfusion. In addition, heart rate and direct arterial blood pressure were measured at each time point.Measurements and Main ResultsSignificant decreases were noted for PCV (P = 0.048), TPP (P < 0.0001), and arterial blood pressures (P < 0.0001) over time. Platelet count did not change significantly (P = 0.879), but platelet function was decreased following hemorrhage when arachidonic acid (P = 0.004) and ADP (P = 0.008) were used as agonists. The TEG variables R (P = 0.030), MA (P = 0.043), and G (P = 0.037) were significantly, albeit mildly, changed following hemorrhage. Significant prolongations in PT (P < 0.0001) and aPTT (P = 0.041), and decreases in fibrinogen concentration (P = 0.002) were also seen.ConclusionPlatelet dysfunction occurred following hemorrhage in this model, despite a stable platelet count. Additionally, significant changes associated with hemorrhage were documented in aPTT, fibrinogen, and MA. Platelet function testing in dogs with naturally occurring hemorrhage warrants further investigation.