bluuebunny/crossref_metadata_2025_split huggingface dataset:
Un dispositif de soins au cœur des troubles spécifiques du langage et de la parole
Authors: Bottero-Frambourg Sylvaine , Cano Cécile , Chalamel Anne-Lise , Duchez Anaïs , Léault Jocelyne , Louvet Nicolas 
Published: November 2016

Les troubles complexes du langage apparaissent comme des symptômes handicapants qui nécessitent une prise en charge pluridisciplinaire dans un lieu de soins tiers en lien avec les différents espaces de vie des jeunes. La présentation du dispositif mis en place par le sessad Bossuet illustre la pertinence d’un accompagnement global pour ces jeunes « dysphasiques ». La rythmicité des soins autour d’un espace intégratif leur permet de tisser leur vécu et d’élaborer leur pensée. L’exemple clinique de Tom met en lumière l’efficience de ce service de soins dans lequel la continuité, la contenance, le respect de l’évolution et de la prise de parole sont des fondamentaux.
Psychopathologie développementale et familiale de la séparation parentale
Authors: Aabbassi Bouchra , Asri Fatima , Nicolis Hélène 
Published: November 2016

La séparation parentale est une expérience à risque traumatique pour l’enfant quel que soit son âge. Pour surmonter cette épreuve, l’enfant met en place des mécanismes adaptatifs soit fonctionnels, lui permettant de poursuivre harmonieusement son développement ; soit au contraire, non fonctionnels donnant lieu à l’apparition de symptômes relevant des registres affectif, familial, relationnel, et/ou scolaire. Toutefois, l’expression de cette souffrance va dépendre de plusieurs facteurs (l’âge de l’enfant, son niveau de développement, sa personnalité et celle de ses parents, le contexte familial, la nature de la mésentente parentale, la place de l’enfant au sein du conflit, la qualité de la relation entre les parents ainsi que celle des relations enfant-parents après la séparation…). Aujourd’hui, les lectures en matière de séparation parentale et ses répercussions psychologiques chez les enfants se multiplient et s’entrecroisent pour apporter un regard plus global à ce phénomène préoccupant. Nous nous proposons ici de faire une revue de la littérature internationale sur ce sujet.
Réflexions autour de la médiation écriture en dispositif groupal
Authors: Marcilhacy Charlotte 
Published: November 2016

La proposition de groupes à médiation paraît répondre de plus en plus aux nouvelles formes d’expression de la souffrance mentale, au plus près des besoins et de la clinique présentée par nos jeunes patients suivis en pédopsychiatrie. À partir de l’expérience de deux groupes écriture, l’un en cattp et l’autre cmp , nous montrons comment, incités à se souvenir à travers une situation d’écriture et des associations partagées, les enfants sont accompagnés dans un processus qui soutient leur créativité, leur pensée, leurs possibilités expressives et communicationnelles, et les revalorise. Face à la réactualisation de vécus corporels et d’éprouvés très primitifs, ils sont encouragés, avec le soutien de l’adulte, à intégrer certains éléments traumatiques de leur expérience en les mettant en forme, en récit, dans un aller-retour entre singularité et acceptation d’un code formalisé, partagé.
Patient safety and error management in endoscopy ATR Axon MD FRCP
Authors: Axon Anthony Thomas Roger 
Published: November 2016

AbstractThis paper addresses the risk of complications in patients who undergo digestive endoscopy, the reasons why they arise and the precautions that should be taken to prevent them. It also considers issues relating to potential litigation and how to minimize this risk. The advice focuses on the importance of maintaining high-quality endoscopic practice including the day-to-day running of the service. It emphasizes the importance of teamwork, the preparation of in-house protocols, patient management before, during, and after the examination, and what measures should be taken in the event that problems do arise. It is an updated and expanded version of an invited lecture given at the Asian Pacific meeting in Bali in 2014 on behalf of the World Endoscopy Organization.
An uncommon cause of unexplained nonbloody diarrhea: When mind knows eyes may see
Authors: Nayak Hemanta Kumar , Verma Abhai , Ghoshal Uday Chand , Pandey Rakesh 
Published: November 2016

AbstractCollagenous colitis (CC) is characterized by chronic secretory diarrhea with the apparently normal gross appearance of the colonic mucosa. A biopsy is usually diagnostic. The symptoms of CC appear most commonly in the elderly. In CC, the major microscopic characteristic is a thickened collagen layer beneath the colonic mucosa. The reported case represents unexplained nonbloody diarrhea of a systemic lupus erythematosus patient, on extensive evaluation found to have CC. This case highlights the importance of considering a rare possibility of CC as a differential in a patient of unexplained nonbloody diarrhea.
Large-scale application of the flood damage model RAilway Infrastructure Loss (RAIL)
Authors: Kellermann Patric , Schönberger Christine , Thieken Annegret H. 
Published: November 2016

Abstract. Experience has shown that river floods can significantly hamper the reliability of railway networks and cause extensive structural damage and disruption. As a result, the national railway operator in Austria had to cope with financial losses of more than EUR 100 million due to flooding in recent years. Comprehensive information on potential flood risk hot spots as well as on expected flood damage in Austria is therefore needed for strategic flood risk management. In view of this, the flood damage model RAIL (RAilway Infrastructure Loss) was applied to estimate (1) the expected structural flood damage and (2) the resulting repair costs of railway infrastructure due to a 30-, 100- and 300-year flood in the Austrian Mur River catchment. The results were then used to calculate the expected annual damage of the railway subnetwork and subsequently analysed in terms of their sensitivity to key model assumptions. Additionally, the impact of risk aversion on the estimates was investigated, and the overall results were briefly discussed against the background of climate change and possibly resulting changes in flood risk. The findings indicate that the RAIL model is capable of supporting decision-making in risk management by providing comprehensive risk information on the catchment level. It is furthermore demonstrated that an increased risk aversion of the railway operator has a marked influence on flood damage estimates for the study area and, hence, should be considered with regard to the development of risk management strategies.
Adolescent Clinical Development of Ezogabine/Retigabine as Adjunctive Therapy for Partial-Onset Seizures: Pharmacokinetics and Tolerability
Authors: Tompson Debra J. , Buraglio Mauro , Andrews Susan M. , Wheless James W. 
Published: November 2016

OBJECTIVES: To explore the pharmacokinetic (PK) profile and safety of ezogabine (EZG)/retigabine (RTG) as adjunctive therapy for uncontrolled partial-onset seizures (POS) in adolescents.
METHODS: In this multiple-dose study (NCT01494584), adolescents with POS received EZG/RTG immediate-release tablets three times daily (TID) as adjunctive therapy to 1 to 3 concurrent antiepileptic drugs. The study comprised a screening phase, and a 5- to 8-week treatment phase starting with 100 mg TID up-titrated once weekly by ≤50 mg TID to a maximum dosage of 300 mg TID. There were 8 venous blood samples and 2 finger-prick blood samples collected for PK analysis during 8-hour time periods at the target dosages of 100, 200, and 300 mg TID.
RESULTS: This study was terminated prematurely on US Food and Drug Administration advice due to pigmentation/discoloration findings in long-term, open-label extension studies in adults. Five participants (ages 13–16 years) had enrolled in the study. For the EZG/RTG 100-, 200-, and 300-mg doses, the area under the concentration-time curve during the dosage intervals was 1680, 2559, and 3784 ng/hr/mL; maximum plasma concentrations were 370, 536, and 751 ng/mL, and minimum plasma concentrations were 105, 200, and 287 ng/mL, respectively. Venous and finger-prick concentrations of EZG/RTG were similar. No significant adverse events were observed during treatment (133–213 days).
CONCLUSIONS: EZG/RTG PK appeared linear across the dosage range of 100 to 300 mg TID in adolescents with POS, and were consistent with adult observations. The small sample size and short study duration preclude conclusions regarding the safety and efficacy of EZG/RTG.
Terahertz emission from biased conjugated polymers excited by femtosecond laser pulses
Authors: Unuma Takeya , Yamada Naruki , Kishida Hideo 
Published: November 2016

Abstract
We perform terahertz emission spectroscopy to investigate the ultrafast motion of electrons and holes in conjugated polymer films excited by femtosecond laser pulses under in-plane bias electric field. The terahertz waveforms are found to exhibit not the features of free carrier acceleration along bias electric field but a characteristic shape reproduced well by the second time derivative of a delta-function-like polarization. Linear-to-quadratic relations between the terahertz emission amplitude and the excitation intensity are observed for three different conjugated polymers, indicating that the polarization is created by either exciton formation or optical rectification involving two-step excitation via localized states.
Lateral carrier confinement of GaN-based vertical-cavity surface-emitting diodes using boron ion implantation
Authors: Hamaguchi Tatsushi , Nakajima Hiroshi , Ito Masamichi , Mitomo Jugo , Satou Susumu , Fuutagawa Noriyuki , Narui Hironobu 
Published: November 2016

Abstract
Boron ion implantation, which is used for confining carriers in gallium nitride (GaN)-based vertical-cavity surface-emitting laser diodes (VCSELs), was studied. Detailed analysis indicated that boron ion implantation of GaN increases GaN’s absorption coefficient from zero to 800 cm−1 and its refractive index from 2.45 to 2.51 at the surface of the wafer at a wavelength of 453 nm. The depth profile of boron obtained by secondary ion mass spectroscopy (SIMS) showed an exponential decrease toward the bottom of the wafer. Assuming that the changes in optical parameters caused by implantation are proportional to the concentration of boron in GaN, the boron ion implantation applied to GaN-VCSELs causes optical absorption of 0.04% per round trip in the cavity and extends the light path of the cavity by 2.2 nm, both of which apparently have negligible impact on the operation of GaN-VCSELs. The implanted boron ions pass through the active regions, introducing non-radiative recombination centers at the edges of those active regions made of InGaN multi-quantum wells, which, however, does not cause significant current injection loss.
Indications of a positive feedback between coastal development and beach nourishment
Authors: Armstrong Scott B. , Lazarus Eli D. , Limber Patrick W. , Goldstein Evan B. , Thorpe Curtis , Ballinger Rhoda C. 
Published: November 2016

AbstractBeach nourishment, a method for mitigating coastal storm damage or chronic erosion by deliberately replacing sand on an eroded beach, has been the leading form of coastal protection in the United States for four decades. However, investment in hazard protection can have the unintended consequence of encouraging development in places especially vulnerable to damage. In a comprehensive, parcel‐scale analysis of all shorefront single‐family homes in the state of Florida, we find that houses in nourishing zones are significantly larger and more numerous than in non‐nourishing zones. The predominance of larger homes in nourishing zones suggests a positive feedback between nourishment and development that is compounding coastal risk in zones already characterized by high vulnerability.
Direct Phosphorus‐Induced Fluoroalkylthiolation with Fluoroalkylsulfonyl Chlorides
Authors: Jiang Lvqi , Yi Wenbin , Liu Qiran 
Published: November 2016

AbstractA simple and practical method of fluoroalkylthiolation using fluoroalkylsulfonyl chlorides (RfSO2Cl, Rf=CF3, C4F9, C8F17, CF2H and CH2CF3) has been developed. These easy‐to‐handle reagents are powerful and can be used for electrophilic fluoroalkylthiolation of electron‐rich arenes and thiols using diethyl phosphite as reducing agent.magnified image
Catalytic Asymmetric [3+2] Cycloadditions of C‐3 Unsubstituted 2‐Indolylmethanols: Regio‐, Diastereo‐ and Enantioselective Construction of the Cyclopenta[b]indole Framework
Authors: Zhu Zi‐Qi , Shen Yang , Sun Xiao‐Xue , Tao Ji‐Yu , Liu Jin‐Xi , Shi Feng 
Published: November 2016

AbstractThe first catalytic asymmetric [3+2] cycloaddition of 2‐indolylmethanols with 3‐vinylindoles has been established, which makes use of C‐3 unsubstituted 2‐indolylmethanol as a C3 building block in the presence of a chiral phosphoric acid. By using this strategy, biologically important cyclopenta[b]indole frameworks were efficiently constructed with regiospecificity in high yields (up to 99%), excellent diastereo‐ and enantioselectivities (up to >95:5 dr, 96:4 er). This reaction not only represents the first catalytic asymmetric [3+2] cycloaddition of C‐3 unsubstituted 2‐indolylmethanols, but also has confronted the great challenges in 2‐indolylmethanol‐involved enantioselective transformations.magnified image
Importance of respiratory rate for the prediction of clinical deterioration after emergency department discharge: a single‐center, case–control study
Authors: Mochizuki Katsunori , Shintani Ryosuke , Mori Kotaro , Sato Takahisa , Sakaguchi Osamu , Takeshige Kanako , Nitta Kenichi , Imamura Hiroshi 
Published: November 2016

AimThe purpose of the present study was to investigate the predictors of clinical deterioration soon after emergency department (ED) discharge.MethodsWe undertook a case–control study using the ED database of the Nagano Municipal Hospital (Nagano, Japan) from January 2012 to December 2013. We selected adult patients with medical conditions who revisited the ED with deterioration within 2 days of ED discharge (deterioration group). The deterioration group was compared with a control group.ResultsDuring the study period, 15,724 adult medical patients were discharged from the ED. Of these, 170 patients revisited the ED because of clinical deterioration within 2 days. Among the initial vital signs, respiratory rate was less frequently recorded than other vital signs (P < 0.001 versus all other vital signs in each group). The frequency of recording each vital sign did not differ significantly between the groups. Overall, patients in the deterioration group had significantly higher respiratory rates than those in the control group (21 ± 5/min versus 18 ± 5/min, respectively; P = 0.002). A binary logistic regression analysis revealed that respiratory rate was an independent risk factor for clinical deterioration (unadjusted odds ratio, 1.15; 95% confidence interval, 1.04−1.26; adjusted odds ratio, 1.15; 95% confidence interval, 1.01−1.29).ConclusionsAn increased respiratory rate is a predictor of early clinical deterioration after ED discharge. Vital signs, especially respiratory rate, should be carefully evaluated when making decisions about patient disposition in the ED.
Metallfreie meta‐selektive Oxyarylierung von Alkinen mit Pyridin‐N‐oxiden: schnelle Synthese von Metyrapon‐Analoga
Authors: Chen Xiangyu , Ruider Stefan A. , Hartmann Rolf W. , González Leticia , Maulide Nuno 
Published: November 2016

AbstractEine effiziente und metallfreie Oxyarylierung von elektronarmen Alkinen ausgehend von Pyridin‐N‐oxiden wurde entwickelt. Die Transformation liefert meta‐substituierte Pyridine analog zum Wirkstoff Metyrapon in hoher Regioselektivität. DFT‐Rechnungen lieferten wichtige Einblicke in den Reaktionsmechanismus. Die Überprüfung der inhibitorischen Eigenschaften ergab Pyridin 4 o mit einer Hemmaktivität im zweistelligen nanomolaren Bereich (wie Metyrapon) als den aktivsten Inhibitor der 11β‐Hydroxylase CYP11B1.
Asymmetric Synthesis of Protected Cyclohexenylamines and Cyclohexenols by Rhodium‐Catalyzed [2+2+2] Cycloaddition
Authors: Masutomi Koji , Sugiyama Haruki , Uekusa Hidehiro , Shibata Yu , Tanaka Ken 
Published: November 2016

AbstractIt has been established that cationic rhodium(I)/axially chiral biaryl bis(phosphine) complexes catalyze the asymmetric [2+2+2] cycloaddition of 1,6‐enynes with electron‐rich functionalized alkenes, enamides, and vinyl carboxylates, to produce the corresponding protected cyclohexenylamines and cyclohexenols. Interestingly, regioselectivity depends on structures of substrates. The present cycloaddition was successfully applied to the enantioselective total synthesis of (−)‐porosadienone by using the amide moiety as a leaving group.
Zero‐Valent Amino‐Olefin Cobalt Complexes as Catalysts for Oxygen Atom Transfer Reactions from Nitrous Oxide
Authors: Gianetti Thomas L. , Rodríguez‐Lugo Rafael E. , Harmer Jeffrey R. , Trincado Monica , Vogt Matthias , Santiso‐Quinones Gustavo , Grützmacher Hansjörg 
Published: November 2016

AbstractThe synthesis and characterization of several zero‐valent cobalt complexes with a bis(olefin)‐amino ligand is presented. Some of these complexes proved to be efficient catalysts for the selective oxidation of secondary and allylic phosphanes, as well as diphosphanes, even with a direct P−P bond. With 5 mol % catalyst loadings the oxidations proceed under mild conditions (25–70 °C, 7–22 h, 2 bar N2O) and afford good to excellent yields (65–98 %). In this process, the greenhouse gas N2O is catalytically converted into benign N2 and added‐value organophosphorus compounds, some of which are difficult to obtain otherwise.
Hydroformylation of Olefins by a Rhodium Single‐Atom Catalyst with Activity Comparable to RhCl(PPh3)3
Authors: Lang Rui , Li Tianbo , Matsumura Daiju , Miao Shu , Ren Yujing , Cui Yi‐Tao , Tan Yuan , Qiao Botao , Li Lin , Wang Aiqin , Wang Xiaodong , Zhang Tao 
Published: November 2016

AbstractHomogeneous catalysts generally possess superior catalytic performance compared to heterogeneous catalysts. However, the issue of catalyst separation and recycling severely limits their use in practical applications. Single‐atom catalysts have the advantages of both homogeneous catalysts, such as “isolated sites”, and heterogeneous catalysts, such as stability and reusability, and thus would be a promising alternative to traditional homogeneous catalysts. In the hydroformylation of olefins, single‐atom Rh catalysts supported on ZnO nanowires demonstrate similar efficiency (TON≈40000) compared to that of homogeneous Wilkinson's catalyst (TON≈19000). HAADF‐STEM and infrared CO chemisorption experiments identified isolated Rh atoms on the support. XPS and XANES spectra indicate that the electronic state of Rh is almost metallic. The catalysts are about one or two orders of magnitude more active than most reported heterogeneous catalysts and can be reused four times without an obvious decline in activity.
Formation and Reactivity of Electron‐Precise B−B Single and Multiple Bonds
Authors: Arrowsmith Merle , Braunschweig Holger , Stennett Tom E. 
Published: November 2016

AbstractRecent years have seen rapid advances in the chemistry of small molecules containing electron‐precise boron–boron bonds. This Review provides an overview of the latest methods for the controlled synthesis of B−B single and multiple bonds as well as the ever‐expanding range of reactivity displayed by B−B multiple bonds.
Microwave‐assisted hydrothermal liquefaction of lignin for the preparation of phenolic formaldehyde adhesive
Authors: Li Yanming , Li Bingzheng , Du Fangli , Wang Yong , Pan Lixia , Chen Dong 
Published: November 2016

ABSTRACTThis study aimed to produce phenolic formaldehyde (PF) adhesives using the liquefaction product of bagasse lignin (LPBL) as a partial substitute for petroleum‐based phenol. Lignin was extracted from bagasse using 93% acetic acid solution and was rapidly degraded in hot‐compressed water by microwave heating using oxalic acid as catalyst. The liquefaction yield reached 78.69% under the optimal reaction condition. Gas chromatography–mass spectrometry (GC/MS) analysis showed that the main chemical compounds of the liquefaction product included mono‐substituted and bis‐substituted phenols, such as 2,6‐dimethoxyphenol, 4‐hydroxybenzaldehyde, and so on. The LPBL was employed to replace a portion of phenol at varying ratios from 0 to 20 wt % in the preparation of PF adhesives. The molecular weight, viscosity, and adhesive strength of LPBL‐PF adhesives were found to be lower than those of pure PF adhesives. With the phenol replaced by LPBL up to 20%, the viscosity and adhesive strength of the resin were 4.046 Pa s and 1.017 MPa, respectively. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44510.
Recent development of centrifugal electrospinning
Authors: Peng Hao , Liu Yong , Ramakrishna Seeram 
Published: November 2016

ABSTRACTAs a high‐output nanoscale fiber production method, centrifugal electrospinning (CES) has attracted increasing attention, and this has fostered its quick development. In this article, we review this technique and summarize its mechanism, characteristics, classification, and process equipment. Furthermore, we classify the effects of several CES process parameters on the fiber properties into three different categories. The mechanisms of these effects on the fiber characteristics are analyzed. Finally, the CES issues are summarized, and some strategic solutions and prospects are proposed. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44578.
In situ polarity functionalization and properties of styrenic triblock copolymers synthesized via RAFT emulsion polymerization
Authors: Fu Xiaowei , Lei Yuan , Yuan Ye , Yan Peiyao , Wang Jiliang , Zhou Changlin , Lei Jingxin 
Published: November 2016

ABSTRACTThe in situ polarity functionalization of the styrenic triblock copolymers was accomplished via the block introduction of polar monomer, n‐butyl acrylate, with the help of reversible addition‐fragmentation chain transfer (RAFT) emulsion polymerization. The polarity functionalization, microphase separation, static and dynamic mechanical properties, water resistance, transparency, and thermal stability of the synthesized polarity‐functionalized triblock copolymers, polystyrene‐block‐poly(n‐butyl acrylate)‐block‐polystyrene (SAS), were extensively studied. The poly(n‐butyl acrylate) (PBA) middle block higher than 10 wt % has the favorable toughening effect on polystyrene (PSt) two‐end block due to the microphase separation in SAS. The glass transition of the continuous plastic phase (mainly composed of PSt block) has a much greater influence on the storage modulus than that of the dispersed rubber phase (mainly composed of PBA block). The polarity‐functionalized SAS has good water resistance, high transparency, and robust thermal stability. The polarity‐functionalized SAS will have such a potential application broadening as polar adhesive. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44603.