bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technology push and demand pull practices for achieving sustainable development in manufacturing industries
Authors: Singla Anuj , Ahuja Inderpreet Singh , Sethi APS 
Published: January 2018

Purpose
The purpose of this paper is to evaluate the significance of various technology push (TP) and demand pull (DP) practices substantial for achieving sustainable development in Indian manufacturing industries. The research crucially examines the effectiveness of TP-DP practices in manufacturing companies.

Design/methodology/approach
An extensive survey of 92 companies in India has been executed to identify improvements made by TP-DP practices, to achieve sustainable development in manufacturing industries. The companies in the survey include medium- and large-scale manufacturing enterprises. The correlations between various TP-DP practices and sustainable development parameters are evaluated and validated using various numerical methods and tools.

Findings
The focus of the paper is on the distinguishable contributions made by TP-DP practices like innovative capability, research and development, corporate strategy, export orientation, stringent implementation of government regulations, transforming capabilities, unionized labor and customer attributes toward achieving sustainable development in manufacturing industries. The inter-relationships between different TP-DP practices with sustainable development parameters are evaluated to effectively manage the goals and objectives of industries related to sustainability and growth. However, it is also acknowledged that manufacturing firms need to work more actively on managing certain practices of TP-DP.

Research limitations/implications
In the present investigation, contributions made by TP-DP practices are evaluated to accomplish sustainable development in Indian manufacturing industries. Hence, the results obtained may need some modifications before applying to other countries. Moreover, issue-wise independent modeling can also be performed to assess the importance of TP-DP practices under specific orientations.

Practical implications
The research gives priority to enhancement in the planning among various TP-DP practices and sustainable development indicators in the industries, to impart TP-DP as important practices to meet the challenges of competent markets worldwide.

Social implications
It has been exhibited from the observations that adequate TP-DP practices can efficiently contribute toward recognition of sustainable development to compete in the highly progressive global market. The results of various inter-relationships among TP-DP practices and sustainable development parameters represent the effectiveness of TP-DP practices for accomplishment of social as well as organizational objectives.

Originality/value
The investigation shows that TP-DP practices are significant initiatives employed by the manufacturing industries for performance improvement and sustainable development. The paper peeks into the research to find out TP-DP issues that need to be assessed efficiently by companies to avail the benefits of sustainable development to meet the challenges posed by international markets.
Role of sialic acid‐containing glycans of matrix metalloproteinase‐9 (MMP‐9) in the interaction between MMP‐9 and staphylococcal superantigen‐like protein 5
Authors: Kurisaka Chisato , Oku Teruaki , Itoh Saotomo , Tsuji Tsutomu 
Published: January 2018

ABSTRACTStaphylococcal superantigen‐like proteins (SSL) show no superantigenic activity but have recently been considered to act as immune suppressors. It was previously reported that SSL5 bound to P‐selectin glycoprotein ligand‐1 (PSGL‐1) and matrix metalloproteinase (MMP)‐9, leading to inhibition of leukocyte adhesion and invasion. These interactions were suggested to depend on sialic acid‐containing glycans of MMP‐9, but the roles of sialic acids in the interaction between SSL5 and MMP‐9 are still controversial. In the present study, we prepared recombinant glutathione S‐transferase‐tagged SSL5 (GST‐SSL5) and analyzed its binding capacity to MMP‐9 by pull‐down assay after various modifications of its carbohydrate moieties. We observed that GST‐SSL5 specifically bound to MMP‐9 from a human monocytic leukemia cell line (THP‐1 cells) and inhibited its enzymatic activity in a concentration‐dependent manner. After MMP‐9 was treated with neuraminidase, its binding activity towards GST‐SSL5 was markedly decreased. Furthermore, recombinant MMP‐9 produced by sialic acid‐deficient Lec2 mutant cells showed much lower affinity for SSL5 than that produced by wild‐type CHO‐K1 cells. Treatment of MMP‐9 with PNGase F to remove N‐glycan resulted in no significant change in the GST‐SSL5/MMP‐9 interaction. In contrast, the binding of GST‐SSL5 to MMP‐9 secreted from THP‐1 cells cultured in the presence of an inhibitor for the biosynthesis of O‐glycan (benzyl‐GalNAc) was weaker than the binding of GST‐SSL5 to MMP‐9 secreted from untreated cells. These results strongly suggest the importance of the sialic acid‐containing O‐glycans of MMP‐9 for the interaction of MMP‐9 with GST‐SSL5.
Negotiating inter‐professional interaction: playing the general practitioner‐pharmacist game
Authors: Bradley Fay , Ashcroft Darren M. , Crossley Nick 
Published: January 2018

AbstractDespite a mutual interest in optimising the benefits of medication for patients, the general practitioner (GP) and community pharmacist (CP) often work in isolation from one another, both physically and figuratively. Sources of tension include pharmacy's ‘shopkeeper’ image, traditional medical hierarchies and potential encroachment on professional boundaries. This article examinesGPandCPperceptions of their interactions and negotiations and, drawing on the works of Stein and Goffman, identifies a set of ‘unwritten’ rules, termed the ‘GP‐pharmacist game’, which involves the concept of ‘face‐work’. Qualitative interviews with 20GPs and 23CPs located in four geographically and demographically different areas in England were conducted during 2010–11. Key rules of the game include the pharmacist avoiding blaming theGP, using discretion in front of patients, and balancing the necessity and frequency of the communication. This article argues that whilst adhering to the ‘GP‐pharmacist game’ may avoid conflict and ‘get the job done’, it may also constrain efforts to meet wider health care policy aims of a more collaborative relationship.
Collecting the World: Female Friendship and Domestic Craft at Bulstrode Park
Authors: Pelling Madeleine 
Published: January 2018

AbstractThis article explores the gendered translation of global objects collected by Margaret Cavendish Bentinck, duchess of Portland (1715‐1785), and displayed in her museum at Bulstrode Park. It does so by engaging with the epistolary and craft productions of women associated with the site, revealing how materials assembled from around the world served to advance Bluestocking values and female friendship. It demonstrates how processes of collecting and crafting served to map a complex and rapidly expanding material world within an elite domestic environment to reflect the carefully cultivated identities of the duchess and her circle.
Human factors in preventing complications in anaesthesia: a systematic review
Authors: Jones C. P. L. , Fawker‐Corbett J. , Groom P. , Morton B. , Lister C. , Mercer S. J. 
Published: January 2018

SummaryHuman factors in anaesthesia were first highlighted by the publication of the Anaesthetists Non‐Technical Skills Framework, and since then an awareness of their importance has gradually resulted in changes in routine clinical practice. This review examines recent literature around human factors in anaesthesia, and highlights recent national reports and guidelines with a focus on team working, communication, situation awareness and human error. We highlight the importance of human factors in modern anaesthetic practice, using the example of complex trauma.
No Impact of Pre‐existing Cardiovascular Disease on Prescribing Patterns of Sulphonylureas in Denmark – A Registry‐based Nationwide Study
Authors: Nilsson Malin , Rungby Jørgen , Lassota Nathan , Jørgensen Andreas D. , Ibsen Rikke , Kjellberg Jakob 
Published: January 2018

AbstractUncertainty exists regarding cardiovascular (CV) safety of sulphonylureas (SUs) as reflected in package labels and treatment guidelines. This study evaluated clinical treatment practice for SUs by analysing prescription patterns for SUs relative to patient history of CV disease (CVD). Patients in Denmark initiating treatment with SU or other anti‐hyperglycaemic drugs during 2006–12 were retrospectively identified using national health registries. Pre‐existing (previous 12 years) overall CVD, coronary heart disease (CHD) and myocardial infarction (MI) were subsequently identified. Proportion of patients with pre‐existing CVD was compared between new users of SU and new users of other anti‐hyperglycaemic drugs. In total, 50,425 (42.2% females, mean ± SD age 63.3 ± 13.5 years) and 190,438 (46.5% females, age 60.3 ± 15.0 years) patients initiated treatment with SU or other anti‐hyperglycaemic drugs, respectively, during 2006–12. The number of patients initiating SU treatment decreased by 63% during 2006–12. The proportion of patients with pre‐existing CVD varied between 46.9% and 49.8% among new SU users versus 39.9% and 44.8% among new users of other anti‐hyperglycaemic drugs. Corresponding proportions for CHD (17.9–19.9% versus 15.4–16.9%) and MI (6.3–7.5% versus 5.8–6.2%) showed the same pattern. Excluding new gliclazide users (9.6% of all new SU users) from the SU definition did not alter the results. Despite a potentially increased CV risk associated with use of SUs, pre‐existing CVD did not decrease clinicians’ relative prescriptions of SUs.
Student survey trends in reported alcohol use and influencing factors in Australia
Authors: Toumbourou John W. , Rowland Bosco , Ghayour‐Minaie Matin , Sherker Shauna , Patton George C. , Williams Joanne W. 
Published: January 2018

AbstractIntroduction and AimsThere is a need to explain reported trends of reduced alcohol and drug (substance) use in school‐aged children in Australia. This study used student survey data collected in the states of Victoria, Western Australia and Queensland to examine trends in substance use and associated influencing factors.Design and MethodsYouth self‐reports were examined from 11 cross‐sectional surveys completed by 41 328 adolescents (average age 13.5 years, 52.5% female) across 109 Australian communities between 1999 and 2015. Multi‐level modelling was used to identify trends in adolescent reports of lifetime alcohol, tobacco and cannabis use, adjusted for age, gender, social disadvantage and minority status. Trends in influencing factors were also examined that included: individual attitudes, and family, school and community environments. Multivariate analyses estimated the main contributors to alcohol use trends.ResultsAlcohol, tobacco and cannabis use all fell significantly from 1999 to 2015. Higher levels of use were observed in Victoria compared to Western Australia or Queensland. Multivariate analyses identified reductions in favourable parent attitudes and lower availability of substances as direct contributors to reducing alcohol use trends. Indicators of school and family adjustment did not show similar trend reductions.Discussion and ConclusionsReductions in adolescent alcohol, tobacco and cannabis use from 1999 to 2015 were associated with similar reductions in parent favourable attitudes and availability of substances. It is plausible that a reduced tendency for parents and other adults to supply adolescent alcohol are implicated in the reductions in adolescent alcohol use observed across Australia.
Short and medium‐term efficacy of sodium glucose co‐transporter‐2 (SGLT‐2) inhibitors: A meta‐analysis of randomized clinical trials
Authors: Monami Matteo , Liistro Francesco , Scatena Alessia , Nreu Besmir , Mannucci Edoardo 
Published: January 2018

AimsSodium glucose co‐transport‐2 (SGLT‐2) inhibitors reduce tubular glucose reabsorption, producing a reduction of blood glucose without stimulating insulin release. The aim of this meta‐analysis was the systematic collection of available data from randomized trials, in order to establish the durability of the efficacy of SGLT‐2 inhibitors on glycaemic control and body mass index.MethodsA meta‐analysis was performed, including all trials with a duration of at least 12 weeks, comparing SGLT‐2 inhibitors with non‐SGLT‐2 inhibitor agents in type 2 diabetes. The principal outcome was the effect of SGLT‐2 inhibitors on hemoglobin A1c (HbA1c) at 12, 24, 52 and 104 weeks. Data on body mass index at the same time points were also collected.ResultsAmong 66 randomized trials, HbA1c reduction at 12, 24, 52 and 104 weeks was 0.63% (0.57; 0.68, 0.63% (0.57; 0.70), 0.66% (0.57; 0.74) and 0.60% (0.40; 0.81), respectively. SGLT‐2 inhibitors showed a greater efficacy than dipeptidyl‐peptidase‐4 inhibitors (DPP‐4i). Sulfonylureas appeared to be superior to SGLT‐2 inhibitors at 12 weeks, but not at 24 and 52 weeks; SGLT‐2 inhibitors produced a greater reduction in HbA1c than did sulfonylureas at 104 weeks. SGLT‐2 inhibitor‐induced weight loss in placebo‐controlled trials appeared to increase progressively with the duration of treatment.ConclusionsSGLT‐2 inhibitors showed a good persistence of efficacy, at least up to 2 years, with a small but significant superiority over DPP‐4i. Sulfonylureas are more effective in the very short term, but less effective in the longer term.
Estimation of high‐temperature fracture parameters for small punch specimen with a surface crack
Authors: Yoon Kee Bong , Nguyen Thanh Tuan 
Published: January 2018

AbstractAn outline of a newly proposed methodology for evaluating creep crack growth (CCG) parameters using cracked small‐punch (SP) specimens is explained. Three‐dimensional finite element analyses were performed to calculate the stress intensity factor along the crack front for a surface crack formed at the centre of a SP specimen. Effects of crack ratio, (a/t); crack aspect ratio, (a/c); and thickness of the specimen, (t), on the fracture parameters were studied. It was observed that the minimum variation of K‐value along the crack front can be achieved when a/c was 0.50 except the location very near the intersection of the crack and free surface. This condition is similar to the case of constant K‐values along the crack front of the conventional compact tension specimen. Thus, it can be argued that the SP specimen with a surface crack is a suitable specimen geometry for CCG testing. The proposed CCG test method was found to be practically applicable for the crack geometry of 0.10 to 0.30 of a/t with constant aspect ratio of 0.50. An estimation of the K and Ct‐parameter under the small scale creep condition was derived. Future work for further development of the suggested CCG testing is discussed.
Validating taxonomic identifications in entomological research
Authors: Packer Laurence , Monckton Spencer K. , Onuferko Thomas M. , Ferrari Rafael R. 
Published: January 2018

Abstract

We surveyed the treatment of taxonomic information in 567 papers published in nine entomological journals in 2016.

The proportion of papers that provide taxonomic data in sufficient detail to permit precise validation of taxonomic identifications is vanishingly small: most did not cite identification methods, most did not state whether identified material had been vouchered, and taxon concepts were almost universally absent in non‐taxonomic papers. Overall, the combination of all three factors was provided less than 2% of the time and almost two‐thirds of all papers provided none of the three.

We suggest that journals should modify the templates used by editors and reviewers by overtly including the following questions:

Are Order and Family named in the title, abstract or keywords?
Are the methods used for identification of all studied taxa stated clearly?
Is it clear who did the identifications, are they named and is their contact information and/or institutional affiliation provided?
Is the literature whereupon these identifications are based cited appropriately? This would include some reference to as thorough a revisional taxon concept statement as possible, preferably from recent revisions if available.
Are exemplars of all focal species (or all sampled individuals) vouchered in a named repository (ideally with contact person name and accession numbers or other means of ready detection)?

Accurate and replicable taxonomic identification is the cornerstone of biology, without which entomological research risks becoming irreproducible and thus not scientific.
Synthesis of dense, fine‐grained hexagonal barium ferrite ceramics by two‐step sintering process
Authors: Zhou Enmin , Zheng Hui , Zheng Liang , Zheng Peng , Ying Zhihua , Deng Jiangxia , Zhou Jijun 
Published: January 2018

AbstractTwo‐step sintering (TSS) process has been used to fabricate hexagonal barium ferrite (BaFe12O19, BaM) ceramics with high density and fine grain size. The densification, microstructure, and magnetic properties were investigated. The sample prepared by the TSS process with the first‐step sintering temperature of 1325°C, the second‐step sintering temperature of 1300°C, and holding time of 20 hours has a density of 98.01 ± 0.25% of the theoretical density (5.29 g/cm3) and exhibits a uniform microstructure with small average grain size (2.92 ± 0.05 μm). In addition, the saturation magnetization of BaM ceramics has been effectively improved and the value is around 69 emu/g, which is close to theoretical saturation magnetization (72 emu/g). Briefly, using the TSS process can obtain dense and fine‐grained BaM ceramics with high saturation magnetization.
PIKKing a way to regulate inflammation
Authors: Quek Hazel , Lim Yi Chieh , Lavin Martin F , Roberts Tara L 
Published: January 2018

AbstractThe phosphoinositide‐3‐kinase like kinases are a family of very large protein kinases. These PI3‐kinase like kinase (PIKK) proteins have well‐established roles in detection and repair of damage to the genome, regulation of the transcriptome and cellular metabolism. Recently there has emerged, evidence for links between these proteins and inflammation. While some of these links come from an increased understanding of the impacts of damage to the cell on inflammatory responses, others suggest that PIKK proteins also have direct roles in regulation of immune responses. Particularly evident is the link between DNA damage and innate immune response pathways. Here, we review recent findings on the PIKK family of proteins and how they impact on inflammation, particularly activation of the innate immune system.
An Aza resveratrol–chalcone derivative 6b protects mice against diabetic cardiomyopathy by alleviating inflammation and oxidative stress
Authors: You Shengban , Qian Jianchang , Sun Chuchu , Zhang Hailing , Ye Shiju , Chen Taiwei , Xu Zheng , Wang Jingying , Huang Weijian , Liang Guang 
Published: January 2018

AbstractInflammation and oxidative stress play a crucial role in the development of diabetic cardiomyopathy (DCM). We previously had synthesized an Aza resveratrol–chalcone derivative 6b, of which effectively suppressing lipopolysaccharide (LPS)‐induced inflammatory response in macrophages. This study aimed to investigate the potential protective effect of 6b on DCM and underlying mechanism. In H9c2 myocardial cells, 6b potently decreased high glucose (HG)‐induced cell fibrosis, hypertrophy and apoptosis, alleviating inflammatory response and oxidant stress. In STZ‐induced type 1 diabetic mice (STZ‐DM1), orally administration with 6b for 16 weeks significantly attenuated cardiac hypertrophy, apoptosis and fibrosis. The expression of inflammatory cytokines and oxidative stress biomarkers was also suppressed by 6b distinctly, without affecting blood glucose and body weight. The anti‐inflammatory and antioxidative activities of 6b were mechanistic associated with nuclear factor‐kappa B (NF‐κB) nucleus entry blockage and Nrf2 activation both in vitro and in vivo. The results indicated that 6b can be a promising cardioprotective agent in treatment of DCM via inhibiting inflammation and alleviating oxidative stress. This study also validated the important role of NF‐κB and Nrf2 taken in the pathogenesis of DCM, which could be therapeutic targets for diabetic comorbidities.
A spike in mechanotransductive adenosine triphosphate release from red blood cells in microfluidic constrictions only occurs with rare donors
Authors: Mancuso Jordan E. , Ristenpart William D. 
Published: January 2018

AbstractObjectiveWan et al (Proc Natl Acad Sci USA, 105, 2008, 16432) demonstrated that RBCs rapidly and transiently release a spike of 300% more ATP shortly downstream from a short microfluidic constriction where the cells experience a sudden increase in shear stress. More recent work by Cinar et al (Proc Natl Acad Sci USA, 112, 2015, 11783), however, yielded no evidence for a similar spike in ATP release downstream of the constriction. Our aim was to determine whether a transient spike in mechanotransduction is the typical response of RBCs to the sudden onset of increased shear.MethodsWe investigate ATP release downstream of a microfluidic constriction for 15 participants using a luciferase‐based photoluminescent assay.ResultsWhile we observe mechanotransductive ATP release from blood drawn from all donors, we find evidence of a spike in ATP concentration after the microfluidic constriction for only 2 of 15 participants. No clear trends in ATP release are found with respect to the magnitude of the applied shear stress, or to the gender, age, or physical activity (Baecke) index of the donor.ConclusionsIn aggregate, all data acquired to date suggest that a spike in mechanotransductive ATP due to a suddenly applied increase in shear stress occurs in blood drawn from only 14% of the population.
Population genomic footprints of host adaptation, introgression and recombination in coffee leaf rust
Authors: Silva Diogo Nuno , Várzea Vítor , Paulo Octávio Salgueiro , Batista Dora 
Published: January 2018

SummaryCoffee leaf rust, caused by Hemileia vastatrix (Hv), represents the biggest threat to coffee production worldwide and ranks amongst the most serious fungal diseases in history. Despite a recent series of outbreaks and emergence of hypervirulent strains, the population evolutionary history and potential of this pathogen remain poorly understood. To address this issue, we used restriction site‐associated DNA sequencing (RADseq) to generate ∼19 000 single nucleotide polymorphisms (SNPs) across a worldwide collection of 37 Hv samples. Contrary to the long‐standing idea that Hv represents a genetically unstructured and cosmopolitan species, our results reveal the existence of a cryptic species complex with marked host tropism. Using phylogenetic and pathological data, we show that one of these lineages (C3) infects almost exclusively the most economically valuable coffee species (tetraploids that include Coffea arabica and interspecific hybrids), whereas the other lineages (C1 and C2) are severely maladapted to these hosts, but successfully infect diploid coffee species. Population dynamic analyses suggest that the C3 group may be a recent ‘domesticated’ lineage that emerged via host shift from diploid coffee hosts. We also found evidence of recombination occurring within this group, which could explain the high pace of pathotype emergence despite the low genetic variation. Moreover, genomic footprints of introgression between the C3 and C2 groups were discovered and raise the possibility that virulence factors may be quickly exchanged between groups with different pathogenic abilities. This work advances our understanding of the evolutionary strategies used by plant pathogens in agro‐ecosystems with direct and far‐reaching implications for disease control.