bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intervention programs and women empowerment: the role of skills acquisition and development and financial independence
Authors: Sanze Nikita , Bamfo Bylon Abeeku , Takyi Lydia Nyankom 
Published: September 2024

Purpose
This study aims to assess the impact of intervention programs on women empowerment in northern Ghana and the role of skills training and financial independence on women empowerment.

Design/methodology/approach
A structured questionnaire, observations and informal interviews were used to gather data using the survey method. The sample consists of 321 girls from the non-formal track STAGE project in the Kasena Nankana West District of the Upper East Region. The data were analyzed using a structural equation model.

Findings
The results show that NGO intervention programs have a significant impact on women’s empowerment, skills acquisition mediates the relationship between NGO intervention programs and women empowerment. Financial independence does not mediate relationships but significantly affects women’s empowerment.

Originality/value
The discussion on women’s empowerment is not without mentioning the support of NGOs intervention programs. However, there is inadequate literature to explore the basic impacts of sponsored intervention programs on women’s empowerment in Ghana. The findings will provide directions for NGOs intervention programs to support women empowerment in Ghana.
Educational leadership during a time of war in Ukraine
Authors: Hudson Christopher , Tigchelaar David , Zastavnyi Anton 
Published: September 2024

PurposeThe purpose of this paper is to explore how two educational leaders are leading their school communities during a time of war in Ukraine.Design/methodology/approachThrough the use of narratives, two of the co-authors of this paper explore the tensions and opportunities they have encountered, and continue to encounter, as educational leaders during a time of war in Ukraine. Particular emphasis is placed upon how the two co-authors are responding in contextually sensitive and productive ways to build a sense of safety and community in their schools.FindingsThe two narratives in this paper demonstrate both leaders displaying a proclivity for building and sustaining collaborative and networked practices to build a sense of safety, stability and belonging for all members of their respective school communities.Originality/valueThis paper offers international insights into school leadership, at all times but especially during the current state of war in Ukraine.
First-gen and the library: a survey of student perceptions of academic library services
Authors: Stocking Edward Harold , Bucy Rosalind , Ramirez-Reyes Carlos 
Published: September 2024

PurposeAlthough a significant share of undergraduates, first-generation college students (FGCS) remain difficult to characterize. Consequently, academic libraries are challenged to identify the services most important to FGCS. This study measured the perceived importance of and satisfaction with library services among undergraduate students at an R1 land-grant university. The study further compared FGCS’s perceptions of library services with those of their non-first generation peers.Design/methodology/approachThe authors measured importance and satisfaction using the Measuring Information Services Outcomes (“MISO”) Survey. They further analyzed responses according to first-generation status. The authors then compared mean scores and used the Wilcoxon rank-sum test to find statistical differences in perceived importance and satisfaction between first-generation and non-first-generation respondents.FindingsThe difference between first-generation and non-first-generation student responses was statistically significant for 35% of library services. FGCS rated library services higher than their non-first-generation peers for both importance and satisfaction. FGCS perceived library services related to physical spaces and access/discovery as most important. Library services that provide student support or access to technology showed strong evidence of difference between first-generation and non-first-generation student responses. The authors also determined the MISO Survey is a measure for assessing FGCS perceptions of library services.Originality/valueThis study adds quantitative evidence to research on FGCS and academic libraries, further demonstrating the importance of library services to FGCS.
Fostering sustainable employability: the nexus of social support and career competencies in healthcare
Authors: Jabeen Qudsia , Nadeem Muhammadi Sabra , Raziq Muhammad Mustafa , Rice John Lewis 
Published: September 2024

PurposeThis study examines the impact of career competencies (CC) (in the form of personal resources) on sustainable employability (SE) under the tenets of the Conservation of Resources theory. Further, we assess the moderating impact of coworker support and supervisor support (work-related social resources) in this relationship.Design/methodology/approachData were collected using survey method from 362 doctors employed in private hospitals in Pakistan. The data were analyzed using structural equation modeling (SEM).FindingsThe results suggests a significant influence of CC on SE. Further, results also reveal that social support received from coworkers moderates the relationship between CC and SE. However, we find that supervisor support does not moderate the said relationship.Originality/valueThis research has clear novelty as SE is a recently defined construct and is still an area with insufficient empirical research. There is increasing interest in identifying the determinants and underlying mechanism of SE. Thus, this study makes contributions to knowledge by investigating CC and social resources as antecedents of SE. This study also offers implications for theory generally, and within the medical practitioner context more specifically.
Destination image branding for world heritage sites: a methodology combining GIS with sentiment analysis
Authors: Sang Kun , Woon Pei Ying , Tan Poh Ling 
Published: September 2024

Purpose
Against the background of the popularity of social media and heritage tourism, this study aims to focus on world heritage sites, proposing a method to examine and compare the digital spatial footprints left by tourists using geographic information systems.

Methodology
By analyzing user-generated content from social media, this research explores how digital data shapes the destination image of WHS and the spatial relationships between the components of this destination image. Drawing on the cognitive-affective model (CAM), it investigates through an analysis of integrated data with more than 20,000 reviews and 2,000 photos.

Innovation
The creativity of this research lies in the creation of a comprehensive method that combines text and image analytics with machine learning and GIS to examine spatial relationships within the CAM framework in a visual manner.

Results
The results reveal tourists' perceptions, emotions, and attitudes towards George Town and Malacca in Malaysia, highlighting several key cognitive impressions, such as history, museums, churches, sea, and food, as well as the primary emotions expressed. Their distributions and relationships are also illustrated on maps.

Implications
Tourism practitioners, government officials, and residents can gain valuable insights from this study. The proposed methodology provides a valuable reference for future tourism studies and help to achieve a sustainable competitive advantage for other heritage destinations.
Role of Child Marriage and Adolescent Childbearing on Hysterectomy Among Married Women in India: A Cross‐Sectional and Time‐to‐Event Analysis
Authors: Datta Biplab Kumar , Tiwari Ashwini 
Published: September 2024

ABSTRACTObjectiveChild marriage forces a girl into adult roles before physical and psychological maturity, which can take a toll on women's health over the life course. This article aims to assess whether child marriage and adolescent childbearing are associated with elevated risk of gynaecologic disorders leading to hysterectomy.DesignCross‐sectional and time‐to‐event analysis.SettingIndia.Population528 816 ever‐married women, aged 20–49 years.MethodsWomen were grouped in four mutually exclusive categories: (i) married adult—not an adolescent mother (reference category), (ii) married adult—adolescent mother, (iii) married child—not an adolescent mother and (iv) married child—adolescent mother. Multivariable logistic regressions were fitted to assess the odds of hysterectomy for these groups. Nonparametric Kaplan–Meier survivor functions were estimated to evaluate survival rates across the groups.Main Outcome MeasuresWhether had a hysterectomy and age when hysterectomy was performed.ResultsCompared to women married as adults, not an adolescent mother, women married in childhood and gave birth in adolescence were 1.87 (95% CI: 1.78–1.96) times more likely to have a hysterectomy. The latter group also had the lowest survival probability for hysterectomy at all ages (e.g., 85.80% [95% CI: 85.41–86.18] at age 49 years as compared to 91.65% [95% CI: 91.37–91.89] for the former group). Women married as children but not adolescent mothers and married as an adult but gave birth in adolescence also had higher odds of hysterectomy—1.40 (95% CI: 1.31–1.50) and 1.53 (95% CI: 1.40–1.66) times of that of the reference group, respectively.ConclusionsOur results, showing a strong relationship between child marriage and hysterectomy, contribute to the literature on later‐life health consequences of child marriage.
Neuropeptides regulate embryonic salivary gland branching through the FGF/FGFR pathway in aging klotho‐deficient mice
Authors: Toan Nguyen Khanh , Kim Soo‐A , Ahn Sang‐Gun 
Published: September 2024

AbstractSalivary gland branching morphogenesis is regulated by the functional integration of neuronal signaling, but the underlying mechanisms are not fully understood in aging accelerated klotho‐deficient (Kl−/−) mice. Here, we investigated whether the neuropeptides substance P (SP) and neuropeptide Y (NPY) affect the branching morphogenesis of embryonic salivary glands in aging Kl−/− mice. In the salivary glands of embryonic Kl−/− mice, morphological analysis and immunostaining revealed that epithelial bud formation, neuronal cell proliferation/differentiation, and the expression of the salivary gland functional marker ZO‐1 were decreased in embryonic ductal cells. Incubation with SP/NPY at E12‐E13d promoted branching morphogenesis, parasympathetic innervation, and epithelial proliferation in salivary glands of embryonic Kl−/− mice. The ERK inhibitor U0126 specifically inhibited neuronal substance‐induced epithelial bud formation in the embryonic salivary gland. RNA‐seq profiling analysis revealed that the expression of fibroblast growth factors/fibroblast growth factors (FGFs/FGFRs) and their receptors was significantly regulated by SP/NPY treatment in the embryonic salivary gland (E15). The FGFR inhibitor BGJ389 inhibited new branching formation induced by SP and NPY treatment and ERK1/2 expression. These results showed that aging may affect virtually the development of salivary gland by neuronal dysfunction. The neuropeptides SP/NPY induced embryonic salivary gland development through FGF/FGFR/ERK1/2‐mediated signaling.
Letter: Association between terlipressin and multidrug‐resistant organism rectal colonization: Authors' reply
Authors: Mücke Marcus M. , Gu Wenyi , Fernandez Javier , Trebicka Jonel 
Published: September 2024

LINKED CONTENTThis article is linked to Mücke et al papers. To view these articles, visithttps://doi.org/10.1111/apt.17899andhttps://doi.org/10.1111/apt.18200
Immune system of fish with special reference to estrogenic immune regulation: A review
Authors: Sinha Ragini , Mandal Dipak Kumar 
Published: September 2024

AbstractFish, first jawed vertebrate group appearing in evolution, have immune system similar to those of mammals. These early animals' innate and adaptive immune systems are completely developed, having head kidney and thymus as primary, spleen and mucosa associated lymphoid tissue as secondary immune organs. The adaptive immunity performs key role in defence against recurring infections and elimination of fish pathogens with the help of its memory cells, T‐cell‐receptors and immunoglobulins. Epidermal secretions including antibacterial peptides, lysozymes, lectins, complement and C‐reactive proteins which function in disruption of antigens, phagocytosis, inflammatory response and mending of tissue injury play a significant role as elements of fish immune system. Fish, however, have greater innate immunity than humans do. Estrogens play crucial role in immunomodulation through nuclear oestrogen receptors, which are found in majority of immune cells and lymphoid organs in fish. There is mounting proof that xenoestrogens, that can attach as agonists to oestrogen receptors, pose significant ecotoxicological risk by disrupting the defence mechanism in fish. Though less potent than natural oestrogen, they can bioaccumulate to finally reach a substantial dose. This review's objective is to give an overview of the fish defence system, its estrogenic regulation and estrogenic‐endocrine disruption.
Translocation (11;14) is a common cytogenetic abnormality in clonal plasma cells in monoclonal immunoglobulin deposition disease
Authors: Bhutani Divaya , Liu Yusha , Chakraborty Rajshekhar , Radhakrishnan Jai , Lentzsch Suzanne , Peters Daniel , Rubinstein Samuel 
Published: September 2024

SummaryMonoclonal Immunoglobulin deposition disease (MIDD) is characterised by deposits of intact monoclonal light chains in the kidney leading to renal dysfunction. In this study, we retrospectively investigated the underlying plasma cell cytogenetic abnormalities in MIDD. CyclinD1 (11;14) translocation was identified in 12/27 (45%) patients. Among the patients without translocation, del13q and hyperdiploidy were the most common abnormalities. Patients in the non‐t (11;14) group had a higher baseline light‐chain ratio, higher proteinuria and lower eGFR as compared to patients with t (11;14). Haematological VGPR or higher was seen in 58% of t (11;14), and 30% without t (11;14), possibly related to higher use of Daratumumab‐based therapy in the t (11;14) group. With a median follow‐up of 750 days, 30% (8/24) progressed to end stage renal disease (ESRD). eGFR <20 mL/min (HR 25, 95% CI 2.09–298, p = 0.01) and 24 urine protein >3 g/24 h (HR 9, 95% CI 1.27–63.90, p = 0.02) at diagnosis were significantly associated with progression to ESRD. Renal survival was better in t (11;14) as compared to the non‐t (11;14) group (HR 0.11, p = 0.06). Translocation (11;14) is a common abnormality in MIDD and affects the presentation and outcomes. Identification of this abnormality should lead to exploration of BCL2 inhibitors in this disease.
Association of N‐terminal pro‐B natriuretic peptide with all‐cause mortality and cardiovascular mortality in obese and non‐obese populations and the development of a machine learning prediction model: National Health and Nutrition Examination Survey (NHANES) 1999–2004
Authors: Zhou Han , Yang Chen , Li Jingjie , Sun Lin 
Published: September 2024

AbstractAimsTo explore the potential of N‐terminal pro‐B natriuretic peptide (NTproBNP) in identifying adverse outcomes, particularly cardiovascular adverse outcomes, in a population with obesity, and to establish a risk prediction model.MethodsThe data for this study were obtained from the National Health and Nutrition Examination Survey (NHANES) for 6772 participants without heart failure, for the years 1999 to 2004. Multivariable Cox regression models, cubic spline restricted models and Kaplan–Meier curves were used to evaluate the relationship between NTproBNP and both all‐cause mortality and cardiovascular mortality. Predictive models were established using seven machine learning methods, and evaluation was conducted using precision, recall, F1 score, accuracy, and area under the curve (AUC) values.ResultsDuring the population follow‐up, out of 6772 participants, 1554 died, with 365 deaths attributed to cardiovascular disease. After adjusting for relevant covariates, NTproBNP levels ≥300 pg/mL were positively associated with both all‐cause mortality (hazard ratio [HR] 3.00, 95% confidence interval [CI] 2.48, 3.67) and cardiovascular mortality (HR 6.05, 95% CI 3.67, 9.97), and remained significant across different body mass index (BMI) strata. However, in participants without abdominal obesity, the correlation between NTproBNP and cardiovascular mortality was significantly reduced. Among the seven machine learning methods, logistic regression demonstrated better predictive performance for both all‐cause mortality (AUC 0.86925) and cardiovascular mortality (AUC 0.85115). However, establishing accurate cardiovascular mortality prediction models for non‐abdominal obese individuals proved challenging.ConclusionThe study showed that NTproBNP can serve as a predictive factor for all‐cause mortality and cardiovascular mortality in individuals with different BMIs, including obese individuals. However, significant cardiovascular mortality correlation was observed only for NTproBNP levels ≥300 pg/mL, and only among participants with abdominal obesity.
Gap detection ability declines with central auditory neurodegeneration following age‐related cochlear synaptopathy
Authors: Kurioka Takaomi , Mizutari Kunio 
Published: September 2024

AbstractAge‐related hearing impairment (ARHI) is commonly associated with decreased auditory temporal resolution caused by auditory neurodegeneration. Age‐related deterioration in gap detection ability, resulting in poor temporal auditory processing, is often attributed to pathophysiological changes in both the peripheral and central auditory systems. This study aimed to investigate whether the gap detection ability declines in the early stages of ageing and to determine its usefulness in detecting peripheral and central auditory degeneration. The study used 1‐month‐old (1 M), 6‐month‐old (6 M) and 12‐month‐old (12 M) mice to examine changes in gap detection ability and associated auditory pathophysiology. Although hearing thresholds did not significantly differ between the groups, the amplitude of auditory brainstem response (ABR) wave I decreased significantly in an age‐dependent manner, consistent with age‐related cochlear synaptopathy. The relative ABR amplitude ratio of waves 2 and 5 to wave 1 was significantly increased in 12 M mice, indicating that the central auditory system had increased in relative neuroactivity. A significant increase in gap detection thresholds was observed in 12 M mice compared to 1 M mice. Although cochlear synaptopathy and central hyperactivity were positively correlated with gap detection thresholds, central hyperactivity strongly influenced gap detection ability. In the cochlear nucleus and auditory cortex, the inhibitory synaptic expression of GAD65 and the expression of parvalbumin were significantly decreased in 12 M mice, consistent with central hyperactivity. Evaluating gap detection performance may allow the identification of decreased auditory temporal resolution in the early stages of ARHI, which is strongly associated with auditory neurodegeneration.
A latent profile analysis of relationship satisfaction and self‐regulation among low‐income participants who attended relationship education with a partner
Authors: Carlson Ryan G. , Wheeler Naomi J. , Liu Xun , Carroll Nakita 
Published: September 2024

AbstractRelationship education has shown promising effects for low‐income couples on outcomes such as promoting positive communication, improving global relationship satisfaction, parenting, and individual psychological distress. Studies also indicate that couples' baseline distress (e.g., relational and individual) moderates outcomes. Yet, few studies implemented a person‐centered approach to analyzing data for those who participate in relationship education. In a sample of 488 low‐income opposite‐gendered couples, we identified latent profile groups for men and women based on self‐reported relationship satisfaction and behavioral self‐regulation scores, thus incorporating both relational and individual factors. Results yielded a three‐class solution for men and a four‐class solution for women. We then examined group profile differences in individual psychological distress and relationship satisfaction change scores after completing the relationship education intervention (12 h of PREP's Within Our Reach). Results indicated significant differences, suggesting that group membership can predict overall improvements in both psychological and relationship distress. Thus, RE programmers and policymakers may consider flexible delivery (e.g., more or less content; more or less intense coaching) that considers overall baseline relational and/or individual functioning as opposed to a one‐size‐fits‐all method.
The Dutch Citizen's Understanding and Perception of the Actors Involved in the Netherlands' COVID‐19 Pandemic Response: A Focus Group Study During the First Pandemic Wave
Authors: Kamga L. S. Kengne , Voordouw A. C. G. , De Vries M. C. , Belfroid E. , Brabers A. E. M. , De Jong J. D. , van Eck L. C. , Koopmans M. P. G. , Timen A. 
Published: September 2024

ABSTRACTIntroductionThe COVID‐19 pandemic was a public health emergency (PHE) of unprecedented magnitude and impact. It provided the possibility to investigate the Dutch citizens' understanding and perception of the actors involved in the Dutch pandemic response as a PHE unfolded.MethodsThree focus groups (FGs) were held with 16 Dutch citizens in June 2020. Citizens were recruited using the Dutch Health Care Consumer Panel. During the FGs, participants were asked to fill in a table with actors they thought were involved in the management of the COVID‐19 pandemic. They also received information on actors involved in Dutch outbreak responses. Then, the actors named and omitted by the participants were discussed.ResultsAn analysis of the FGs suggests that the Dutch citizens participating in the study were not fully aware of the scope of actors involved in the Dutch COVID‐19 pandemic response. Some participants would have appreciated more information on the actors involved. This would help them have an informed opinion of the actors involved in the decision‐making process, and accept non‐pharmaceutical interventions implemented. Lastly, most participants recognised that they played a role in limiting the spread of the COVID‐19 pandemic. Yet, very few spontaneously mentioned themselves as actors within the COVID‐19 pandemic response.ConclusionThis study suggests that early in the COVID‐19 pandemic, the Dutch citizens participating in this study's FG did not have a complete understanding of the scope of actors involved in the Dutch COVID‐19 pandemic response, or the potential role of the citizen. Future research can build on these results to explore the citizen's perception of their role during PHEs of another origin, as well as other geographical and historical contexts.Patient or Public ContributionThe public participated in the focus groups and received a non‐expert report summarising the outcomes of the focus groups.