bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of muscle quantity, muscle quality, and phase angle on whole-body reaction time in 5164 adults aged 20–91 years
Authors: Fukuda Wataru , Yoshihisa Takeshi , Yamada Yosuke 
Published: September 2024

Abstract

Purpose
Muscle quantity, defined as appendicular lean mass (ALM); muscle quality, defined as the ratio of muscle strength to ALM; and bioelectrical impedance analysis (BIA)-derived phase angle (PhA) are determinants of physical performance. We examined whether muscle quality indices were significant predictors of the whole-body reaction time (WBRT) in healthy female and male adults aged 20–91 years.

Methods
Data from 5164 adults (2869 women and 2295 men; mean age ± standard deviation, 60.9 ± 15.6 years) were analyzed. Height and weight were measured, and body mass index was calculated. ALM was estimated using a previously validated 8-electrode multi-frequency BIA. PhA was measured at 50 kHz using a BIA device. Knee extension strength (KES), leg extension power (LEP), and flexibility were examined. The ALM to weight (ALM/weight), KES to ALM (KES/ALM), and LEP to KES (LEP/KES) ratios were calculated. In the WBRT test, participants were asked to stand on a force plate and jump upright as quickly as possible in response to a light stimulus. The WBRT was divided into the response initiation and motion execution phases.

Results
ALM/weight, KES/ALM, LEP/KES, PhA, and flexibility were significant independent predictors of WBRT and the time of the motion execution phase (p < 0.001). However, PhA was not a significant predictor of the time of response initiation phase.

Conclusion
Muscle quantity (ALM/weight), muscle quality (KES/ALM and LEP/KES), PhA, and flexibility are determinants of WBRT test performance, particularly in the motion execution phase.
Short-term primary and revision modular dual-mobility cup total hip arthroplasty outcomes in high-risk dislocation patients: a retrospective study
Authors: Ruusiala Martta , Miettinen Hannu , Kettunen Jukka , Kröger Heikki , Miettinen Simo 
Published: September 2024

Abstract
Purpose
Modular dual-mobility cups (MDMCs) have a lower risk for dislocation after total hip arthroplasty (THA). The primary aims of our study were to analyze implant survivorship and to determine complications, especially dislocation, and revision rates of primary THAs used for hip fracture patients and for revision THAs. Secondary aims were to evaluate mortality after MDMC surgery and to find out if introduction of MDMC at our institution (Kuopio University Hospital, Finland) have decreased dislocation rate.

Methods
This retrospective cohort study consisted of 101 MDMC patients who were consecutively operated at our institution between April 1, 2018 and June 30, 2020. The implant survival rate, complications and mortality were evaluated with minimum of 2-year follow-up. Finnish Hospital Discharge Register was used to find out yearly dislocation rates following THA at our institution.

Results
The cumulative estimate implant survival after MDMC in the primary THA group was 97% at 2 years, and in the revision THA group, it was 90% at 2 years. Dislocation was a rare complication in the primary THA group (1.4%), while it was common in revision THA group (12.9%). The cumulative estimate for mortality after MDMC in the primary THA group was 13% at 2 years, and in the revision group, it was also 13% at 2 years. The yearly number of patients who had re-hospitalization period due to THA dislocation decreased 46% after implementation of MDMC.

Conclusion
Short-term survival and complication rates after MDMC were excellent after primary THA and moderate after revision THA. Implementation of MDMC THA for hip fracture patients seems to have effectively decrease dislocation rate during a short follow-up.
MILP and PSO approaches for solving a hydropower reservoirs intraday economic optimization problem
Authors: Castro-Freibott Rodrigo , García-Castellano Gerbolés Carlos , García-Sánchez Alvaro , Ortega-Mier Miguel 
Published: September 2024

AbstractShort-term hydropower generation with several water reservoirs requires deciding, for each moment in time, the volume of water (outflow) that is released from every reservoir to be turbined and generate energy. Knowing the price of energy at every time period, the objective is to maximize the income earned from the generated energy. In this paper, we present (1) a Hydropower Reservoirs Operation Optimization problem with a higher level of detail than those found in the literature, encompassing temporal delays, water hammer effects, and increased temporal discretization, among others features, and (2) two distinct approaches for addressing this problem: MILP and PSO. These methods are compared across instances of varying nature to evaluate their performance. We make our code available on GitHub: https://github.com/baobabsoluciones/flowing-basin.
Convergent evolution revealed by paraphyly and polyphyly of many taxa of oribatid mites: A molecular approach
Authors: Cordes Peter , Pan Xue , Murvanidze Maka , Seniczak Anna , Scheu Stefan , Schaefer Ina , Maraun Mark , Heimburger Bastian 
Published: September 2024

AbstractA reliable phylogeny is crucial for understanding the evolution and radiation of animal taxa. Phylogenies based on morphological data may be misleading due to frequent convergent evolution of traits—a problem from which molecular phylogenies suffer less. This may be particularly relevant in oribatid mites, an ancient soil animal taxon with more than 11,000 species, where the classification of species into high-ranking taxa such as superfamilies is equivocal. Here, we present a molecular phylogeny of 317 oribatid, 4 astigmatid and 17 endeostigmatid mite species/taxa based on 18S rDNA sequences. We aimed at testing the validity of the 41 superfamilies of oribatid mites recognized by Norton and Behan-Pelletier (in Krantz and Walter, A manual of Acarology, 3rd ed., Texas Technical University Press, Lubbock, 2009). The results indicate that 17 of the 41 oribatid mite superfamilies are monophyletic but that 18 superfamilies are paraphyletic or polyphyletic (5 superfamilies were only included with one species and Microzetoidea were not included). Our findings point to the importance of convergent evolution in polyphyletic oribatid mite taxa. Convergent evolution and the old age of mites likely resulted in a mosaic-like distribution of morphological characters impeding phylogenetic reconstructions based on morphology, calling for molecular approaches to improve oribatid mite systematics.
Computation in Context
Authors: Curtis-Trudel André 
Published: September 2024

AbstractUnlimited pancomputationalism is the claim that every physical system implements every computational model simultaneously. Some philosophers argue that unlimited pancomputationalism renders implementation ‘trivial’ or ‘vacuous’, unsuitable for serious scientific work. A popular and natural reaction to this argument is to reject unlimited pancomputationalism. However, I argue that given certain assumptions about the nature of computational ascription, unlimited pancomputationalism does not entail that implementation is trivial. These assumptions concern the relativity and context sensitivity of computational ascription. Very roughly: relative to a specific, contextually salient way of regarding a physical system computationally, the claim that that system implements a specific computational model is as non-trivial as one could reasonably want.
Identification of Capsicum species from Colombia by DNA barcoding and high resolution melting (HRM) analysis
Authors: Viáfara-Vega Ronald A. , Cárdenas-Henao Heiber 
Published: September 2024

Abstract
DNA barcoding allows the use of molecular markers to differentiate the species of an interest group. This is especially useful when morphological characters are insufficient due to high similarity between species. The genus Capsicum contains some species that are difficult to determine by taxonomic means, in particular the annuum complex. Thus, the objective of this study was to investigate the discriminatory ability of two molecular markers in Colombian Capsicum accessions, including three wild species belonging to the Andean clade of the genus. A total of 95 Capsicum accessions, representing eight species, were genotyped by high resolution melting analysis (HRM) using the Waxy and C2_At5g04590 markers. Waxy could discriminate the Andean clade species (C. rhomboideum, C. dimorphum and C. lycianthoides), C. baccatum, C. pubescens and C. chinense, while C2_At5g04590 could discriminate C. frutescens, C. annuum var. annuum and C. annuum var. glabriusculum. Hence, a combination of the two markers could be used for discrimination of the eight species including the wild variety of C. annuum: C. annuum var. glabriusculum. Most nucleotide substitutions and indels were found in the sequences of the three Andean species, indicating that the Andean clade has a high genetic diversity compared to the other species. The incorporation of more wild species and varieties in this study allowed to correct the power of both markers to discriminate Capsicum species, besides the registration of new haplotypes.
Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients
Authors: Geurts Yvonne M. , Peters Femke , Feldman Esther , Roodhart Jeanine , Richir Milan , Dekker Jan Willem T. , Beets Geerard , Cnossen Jeltsje S. , Bottenberg Patricia , Intven Martijn , Verheij Marcel , de Ligt Kelly M. , Walraven Iris 
Published: September 2024

Abstract
Purpose
Standardized patient-reported outcomes (PRO) monitoring during and after rectal cancer treatment provides insight into treatment-related toxicities patients experience and improves health-related quality-of-life as well as overall survival. We aimed to select a subset of the PRO version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) for standardized monitoring of treatment-related symptomatic toxicities in rectal cancer.

Methods
We used a mixed methods approach including a literature review, and semi-structured interviews with health care providers (HCPs) involved in rectal cancer care and rectal cancer patients. Results from literature and interviews were summarized and used in a modified Delphi procedure to select a PRO-CTCAE subset specific for rectal cancer.

Results
Twenty-six PRO-CTCAE symptomatic toxicities were identified from literature. Fifteen HCPs from multiple disciplines (medical, radiation and surgical oncology), and a heterogeneous group of fifteen rectal cancer patients treated with chemotherapy and/or radiotherapy and/or surgery, participated in semi-structured interviews. Ten HCPs (67%) and nine patients (90%) participated in the first Delphi round. The final selected PRO-CTCAE core-subset contained 16 symptomatic toxicities: ‘diarrhea’, ‘fecal incontinence’, ‘constipation’,‘bloating of the abdomen’, ‘pain in the abdomen’, ‘vomiting’, ‘decreased libido’, ‘pain during vaginal sex’, ‘ability to achieve and maintain erection’, ‘fatigue’, ‘anxiety’, ‘feeling that nothing could cheer you up’, ‘urinary incontinence’, ‘painful urination’, ‘general pain’, and ‘hand-foot syndrome’.

Conclusion
Based on a comprehensive mixed methods study, a PRO-CTCAE subset for standardized treatment-related symptomatic toxicity monitoring in rectal cancer was identified. Assessment of the effectiveness and compliance of symptomatic toxicity monitoring using this subset is recommended.
Location, Location, Quality:The Fixed Differentiation Principle
Authors: Cohen Alon , Heifetz Aviad 
Published: September 2024

AbstractThis work revisits the classic spatial duopoly location-then-prices competition with quadratic transportation costs, in the presence of vertical differentiation. We show that contrary to the substitutability between horizontal and vertical differentiation that has appeared thus far in the literature, higher-quality asymmetry does not affect locational differentiation in equilibrium. While the better-quality seller indeed approaches the city center, the worse-quality seller is simultaneously driven further away from the city, and ultimately out of the market when quality differences become large enough. Interestingly, although vertical differentiation weakens competition, total welfare increases – even when the better-quality seller ultimately monopolizes the market.
Multimodal nonlinear correlates of behavioural symptoms in frontotemporal dementia
Authors: Zamboni Giovanna , Mattioli Irene , Arya Zobair , Tondelli Manuela , Vinceti Giulia , Chiari Annalisa , Jenkinson Mark , Huey Edward D. , Grafman Jordan 
Published: September 2024

AbstractStudies exploring the brain correlates of behavioral symptoms in the frontotemporal dementia spectrum (FTD) have mainly searched for linear correlations with single modality neuroimaging data, either structural magnetic resonance imaging (MRI) or fluoro-deoxy-D-glucose positron emission tomography (FDG-PET). We aimed at studying the two imaging modalities in combination to identify nonlinear co-occurring patterns of atrophy and hypometabolism related to behavioral symptoms. We analyzed data from 93 FTD patients who underwent T1-weighted MRI, FDG-PET imaging, and neuropsychological assessment including the Neuropsychiatric Inventory, Frontal Systems Behavior Scale, and Neurobehavioral Rating Scale. We used a data-driven approach to identify the principal components underlying behavioral variability, then related the identified components to brain variability using a newly developed method fusing maps of grey matter volume and FDG metabolism. A component representing apathy, executive dysfunction, and emotional withdrawal was associated with atrophy in bilateral anterior insula and putamen, and with hypometabolism in the right prefrontal cortex. Another component representing the disinhibition versus depression/mutism continuum was associated with atrophy in the right striatum and ventromedial prefrontal cortex for disinhibition, and hypometabolism in the left fronto-opercular region and sensorimotor cortices for depression/mutism. A component representing psychosis was associated with hypometabolism in the prefrontal cortex and hypermetabolism in auditory and visual cortices. Behavioral symptoms in FTD are associated with atrophy and altered metabolism of specific brain regions, especially located in the frontal lobes, in a hierarchical way: apathy and disinhibition are mostly associated with grey matter atrophy, whereas psychotic symptoms are mostly associated with hyper-/hypo-metabolism.
Geotourism and Geoeducation: A Holistic Approach for Socioeconomic Development in Rural Areas of Los Santos Municipality, Santander, Colombia
Authors: Carrillo-Hernández Yeison Mauricio , Ríos-Reyes Carlos Alberto , Villarreal-Jaimes Carlos Alberto 
Published: September 2024

AbstractThis study emphasizes the untapped geotourism and geoeducation potential in the Mesa de Los Santos region, situated within the Chicamocha Canyon in Colombia, renowned for its abundant geoheritage. Despite the region's geological richness, geotourism development opportunities have been overlooked, leaving its geoheritage largely unexplored for tourism. Focused on the georoute Refugio La Roca—Los Santos, the study identifies key geosites with significant potential for future geotourism endeavors. The Mesa de Los Santos region boasts a complex geological history and diverse geodiversity shaped by various natural phenomena. However, its full geotourism potential remains undiscovered. The georoute, incorporating natural and cultural heritage, is strategically designed for geotourism and geoeducation, aiming at fostering geoconservation in rural areas. Educational and interpretive panels are employed as didactic resources to enlighten tourists about the natural phenomena shaping the landscape, enhancing their overall experience and understanding. By integrating geoethical considerations into geosite management, the study proposes achieving sustainable geoconservation in the Chicamocha Canyon territory. This approach not only contributes to preserving the region's geological uniqueness but also provides a platform for socio-economic development in rural areas. The study envisions creating meaningful experiences that attract tourists while benefiting local communities, thereby promoting holistic and sustainable rural development.
Investigation of Effective Notch Stress at the Root of the Rib-to-Deck Weld in an OSD Box Girder Bridge Considering the Wheel Load Position
Authors: Uaje Mark Joel Bañares , Murakoshi Jun 
Published: September 2024

AbstractFatigue cracks have been reported in orthotropic steel deck bridges under severe traffic conditions in Japan, particularly root-deck and bead cracks, which initiate from the root of the rib-to-deck weld. The local stress directly influencing crack initiation was investigated using a finite element model based on a section of an actual bridge with a high incidence of cracks. The analysis focused on the weld root at the floor beam intersection and the span center of the bridge section. The model was subjected to loading in the transverse and longitudinal direction of the bridge combined with various wheel load configurations. The effect on the local stress properties was analyzed using the effective notch stress approach. A load position slightly off-center of the U-rib resulted in peak stress at the study locations. Its principal stress direction angle around the notch suggests a root-deck type of crack initiation. Testing several pavement stiffnesses revealed that using an SFRC pavement resulted in a 76%–84% reduction of peak effective notch stress compared to asphalt pavement. Furthermore, varying weld configurations demonstrated that lowering the weld penetration rate could alter the local stress position, influencing the crack initiation direction.
Production of hydrochar from the hydrothermal carbonisation of food waste feedstock for use as an adsorbent in removal of heavy metals from water
Authors: Pasipanodya Danai , Seedat Naadhira , Patel Bilal , Roopchund Rishen 
Published: September 2024

AbstractIn this research, discarded butternut peels were converted into hydrochar products through hydrothermal carbonisation (HTC), with adjustments made to the temperature (ranging from 180 to 260℃) and residence time (spanning 45–180 min). The findings indicated that both the temperature and time of carbonisation significantly influenced the yield of hydrochar (HC), as well as its physiochemical and structural properties. Higher temperatures and prolonged residence time led to decreased yield, elevated fixed carbon content and an increased fuel ratio. Furthermore, raising the process conditions increased HHV and reduced the oxygen-containing functional groups. The HC yield dropped from 28.75 to 17.58% with increased carbonisation temperature and time. The findings of this study also suggest that modified hydrochar is a promising material for removing heavy metals from wastewater. It is a relatively low-cost and abundant material that can be produced from various biomass feedstocks, including food waste. In addition, it is a sustainable and environmentally friendly option for wastewater treatment. Hydrochar-based systems offer several advantages over traditional methods of heavy metal removal, such as chemical precipitation and ion exchange. The unique physicochemical characteristics of hydrochar, including its porous structure and oxygen-rich functional groups, offer a high surface area and more binding sites for heavy metal ions. By changing the physicochemical properties of hydrochar with chemicals like phosphoric acid, it is possible to increase its adsorption capacity. The Freundlich isotherm was the best fit for the adsorption data for all three metal ions (Pb2+, Cu2+ and Cd2+), indicating that the adsorption process is multilayer and heterogeneous.
Perchlorate in antarctica, origin, effects, treatments, environmental fate, and astrobiological perspectives: a review
Authors: Acevedo-Barrios R. , Puentes Martínez D. A. , Hernández Rocha I. O. , Rubiano-Labrador C. , De la Parra-Guerra A. C. , Carranza-López L. , Monroy-Licht A. , Leal M. A. , Tovar D. 
Published: September 2024

Abstract
Perchlorate (ClO4
−), which is a powerful endocrine disruptor affecting iodine fixation in the thyroid gland in humans and in biota, is a pollutant of natural and anthropogenic origin. For this reason, this pollutant must be eliminated from the ecosystems. It has been found in extreme environments such as Antarctica. ClO4
− reduction can be achieved with physicochemical treatments in small concentrations and through bacterial degradation. This is a cost-effective method, easy to implement, which makes it a viable method for the removal of perchlorate contamination in ecosystems. This review provides an updated discussion of reducing perchlorate contamination; that includes different perspectives of investigations related to its origin, use, effects on living beings; as well as the technologies used to eliminate this pollutant from the environment; its environmental fate in strategic ecosystems such as Antarctica in particular and astrobiological perspectives.
Maternal Streptococcus agalactiae colonization in Europe: data from the multi-center DEVANI study
Authors: Lohrmann Florens , Efstratiou Androulla , Sørensen Uffe B. Skov , Creti Roberta , Decheva Antoaneta , Křížová Pavla , Kozáková Jana , Rodriguez-Granger Javier , De La Rosa Fraile Manuel , Margarit Immaculada , Rinaudo Daniela , Maione Domenico , Telford John , Orefici Graziella , Kilian Mogens , Afshar Baharak , Melin Pierrette , Berner Reinhard , Hufnagel Markus , Kunze Mirjam ,   DEVANI Study Group, Poulsen K , Karstens L , Baldassarri L , Rigat F , Berardi A , Imperi M 
Published: September 2024

Abstract

Introduction
Despite national guidelines and use of intrapartum antibiotic prophylaxis (IAP), Streptococcus agalactiae (group B streptococci (GBS)) is still a leading cause of morbidity and mortality in newborns in Europe and the United States. The European DEVANI (Design of a Vaccine Against Neonatal Infections) program assessed the neonatal GBS infection burden in Europe, the clinical characteristics of colonized women and microbiological data of GBS strains in colonized women and their infants with early-onset disease (EOD).

Methods
Overall, 1083 pregnant women with a GBS-positive culture result from eight European countries were included in the study. Clinical obstetrical information was collected by a standardized questionnaire. GBS strains were characterized by serological and molecular methods.

Results
Among GBS carriers included in this study after testing positive for GBS by vaginal or recto-vaginal sampling, 13.4% had at least one additional obstetrical risk factor for EOD. The five most common capsular types (i.e., Ia, Ib, II, III and V) comprised ~ 93% of GBS carried. Of the colonized women, 77.8% received any IAP, and in 49.5% the IAP was considered appropriate. In our cohort, nine neonates presented with GBS early-onset disease (EOD) with significant regional heterogeneity.

Conclusions
Screening methods and IAP rates need to be harmonized across Europe in order to reduce the rates of EOD. The epidemiological data from eight different European countries provides important information for the development of a successful GBS vaccine.