bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experiências e prospecções do letramento audiovisual no Instituto Federal de Ciência, Tecnologia E Educação – campus Santos Dumont
Authors: Rabello Silva João Gabriel , Júlio Guedes Pinto Priscila 
Published: October 2024

Este artigo objetiva a­presentar a importância do letramento audiovisual para o desenvolvimento de uma educação emancipatória, visto que a pandemia do novo coronavírus evidenciou o quanto as competências midiáticas são pouco desenvolvidas no Brasil. Com base nisso, discute-se não só o termo literacia, como também a construção histórica do conceito de literacia midiática ou educação para a mídia, através de teóricos da educação e da Declaração de Grunwald. Apoiado em ideias do filósofo Vilém Flusser, há a defesa da importância do desenvolvimento das competências midiáticas no contexto da educação técnica e tecnológica, com um breve panorama da educação técnica no Brasil, que acarreta a criação dos Institutos Federais. Por fim, analisa-se as experiências com letramento audiovisual ocorridas no Instituto Federal de Educação, Ciência e Tecnologia do Sudeste de Minas Gerais, campus Santos Dumont, prospectando o potencial para desenvolvimento de projetos de extensão que promovam a experimentação cinematográfica para estudantes.
Aspectos metodológicos do estudo Comercialização de Alimentos em Escolas Brasileiras (Caeb)
Authors: Canuto Raquel , Gomes Ferreira Clark Sabrina , Delazari Borges Luiza , Pereira de Castro Júnior Paulo César , Ferreira Tavares Letícia , De Oliveira Cardoso Letícia , Silva do Carmo Ariene , Loures Mendes Larissa 
Published: October 2024

Apresenta os aspectos metodológicos da concepção e organização do estudo Comercialização de Alimentos em Escolas Brasileiras, que teve como objetivo avaliar aspectos relacionados à comercialização de alimentos e bebidas em escolas privadas, a partir de informações coletadas com gestores de cantinas escolares e ambulantes presentes no entorno imediato das escolas. Realizou-se um estudo transversal em escolas privadas, de ensino fundamental e médio que possuíam cantinas, nas 26 capitais brasileiras e no Distrito Federal. Foi empregada aleatória simples com reposição inversa, ao final, foram avaliadas 2.241 cantinas e 700 ambulantes. A proporção de perdas amostrais foi de 21,2%. O questionário foi desenvolvido e avaliado por especialistas contemplando questões sobre: informação alimentar e nutricional, infraestrutura para alimentação, conveniência, preço, disponibilidade, variedade e promoção. A logística contou com uma equipe coordenadora que conduziu os treinamentos, realizou a gestão e controle da qualidade dos dados, pesquisadores locais e uma empresa que auxiliaram no trabalho de campo. As coletas ocorreram entre 2022 e 2024. As principais dificuldades de implementação foram sua concomitância com o período eleitoral de 2022, episódios de violência nas escolas, políticas internas das escolas e a complexidade da diversidade cultural e a vasta extensão territorial brasileira. Como pontos fortes destacam-se o ineditismo dos dados coletados em profundidade e representatividade, o uso das evidências geradas para proposição de políticas públicas de regulação do ambiente alimentar escolar e o apoio na construção de uma rede de pesquisadores na temática.
The challenging concept of eradication: A core concept guiding and frustrating public health
Authors: Caplan Arthur , Mamo Nathaniel 
Published: October 2024

AbstractThe celebrated 1980 announcement that smallpox had been eradicated was made using the following definition of eradication: “Permanent reduction to zero of the worldwide incidence of infection caused by a specific agent as a result of deliberate efforts: intervention measures are no longer needed.” Public health around the world works with this definition of “eradication,” setting it as a goal for other infectious disease control programs. The definition is simple. Its application, however, has produced long-running and complex public health campaigns that threaten the commitment of funders, health care providers, and governments. In this paper, the authors demonstrate the disease-specific challenges of eradication through the example of the Global Polio Eradication Initiative (GPEI). While many deem eradication worth its high costs because it is the end of morbidity and mortality from a disease, it does not mean the end of disease control efforts. Public health must be prepared for the possibility of disease reoccurrence in the form of undetected natural reservoirs of disease, lab leaks from stored samples, bioterror attacks using stolen samples, and the synthetic recreation of microbes. This paper clarifies the role of reoccurrence prevention in eradication, calling for its addition in the definition of eradication.
Participation of the Central Regional Scientific Library in the Educational Process of Universities
Authors: Sharpilova G. A. 
Published: October 2024

The emergence of new information channels and methods of distributing scientific publications, active development of digital technologies are changing the tasks and forms of work of scientific libraries, which form documentary and information resources and have extensive experience in meeting the information needs of representatives of the scientific and educational complex. The directions of scientific libraries’ activities are complemented by purposeful training of users in the basics of information culture.In scientific libraries – libraries of universities and central scientific libraries of the subjects of the Russian Federation – much attention is paid to servicing students. The change in the educational model, strengthening of the self-educational component in the educational process of the university, the increasing importance of the information culture of the individual change the status of scientific libraries: from an element of the information infrastructure, the library turns into a subject of educational activity, interacting with faculties and departments on the principles of partnership.The purpose of this article is to present the results of the survey of the information behavior of students in Chelyabinsk, who use in their work, along with information resources of university libraries, document and information resources of the Chelyabinsk State Universal Scientific Library and to determine areas of cooperation between the Central Regional Scientific Library and higher educational institutions.
Preservation of the Documentary Heritage for the Socio-Economic Development of the Region: the Experience of the Central Library of RF Constituent Entity and the University of Culture
Authors: Taranenko L. G. 
Published: October 2024

The article is devoted to the study of the documentary heritage, its role in the socio-economic development of the region. The author highlighted the basic requirements of regulations in preserving the documentary heritage in the region. The purpose of the article is to show the library and university capabilities in implementing tasks to preserve and promote cultural heritage for the further development of the territory on the basis of the results of the conducted research.Using the example of the Kemerovo region (Kuzbass), the main parameters of the documentary heritage usage for socio-economic development of the region are determined: ensuring preservation of the documentary heritage; providing access to information; information support for all aspects of regional development; creating digital content of memory institutions (libraries, museums, archives); promoting the documentary heritage; putting into scientific circulation new components of the documentary heritage; research activities; integration of memory institutions for to preserve cultural heritage. The article presents the description of the digital documentary heritage of Kuzbass in the central library (V. D. Fedorov State Scientific Library of Kuzbass). The main types of work of the Kemerovo State Institute of Culture (KemSIC) in preserving and promoting the cultural heritage of Kuzbass are outlined.The article also considers the integration of the activities of the central library with the culture university as one of the key factors in increasing the efficiency of work in this direction. It is emphasized that cooperation between libraries and other institutions and organizations, including authorities and local self-government allows to work out and implement joint projects aimed at developing the region and increasing its level of sustainability. It is noted that the central libraries of the constituent entities of the Russian Federation and the Universities of Culture are key participants in the preservation and development of the cultural heritage of the region.The main conclusion of the study: close integration of the library and the university makes it possible to solve complex problems of preserving and promoting the documentary heritage of the region.
Examining the Influence of ICT Penetration on Gender Disparities: A Data Panel Econometric Analysis of the Seven Southeast Asian Developing Countries
Authors: Wijaya Chandra Henryawan , Basyir Naail Daffa , Hasudungan Albert , Desfiandi Alvin 
Published: October 2024

The aim of the study is to analyze to which Information and Communications Technology (ICT) penetration affects gender disparities in seven Southeast Asia’s developing countries. ICT indicators are measured through the individuals using the internet, mobile phone subscriptions, and internet subscriptions. Aside, the seven Southeast Asia’s developing countries include Indonesia, Cambodia, Laos, Malaysia, Thailand, Philippines, and Vietnam. These countries are selected as they have comparable economic development stage from lower to upper-middle income economics on the basis 2022’s World Bank Country Income Classification. The data panel econometrics is carried out to measure the effect of the independent variables towards gender disparity. Gender disparity is represented by the Gender Inequality Index. The time series data is yearly from 2000 to 2022. The econometric assessment shows the individual internet ownership and subscription have a negative and significant effect to gender disparity. It means that more internet penetration can lower the gender disparity in those seven countries. The academic implication is to enhance economic consideration towards more internet penetration and access to reduce gender disparity. In the heart of policymaking, our research indicates more internet accessibility to reduce gender disparity. As in the common knowledge, the internet is a source of information and knowledge to society
Health Care Delivery Site– and Patient-Level Factors Associated With COVID-19 Primary Vaccine Series Completion in a National Network of Community Health Centers
Authors: Gold Rachel , Steeves-Reece Anna , Ochoa Aileen , Oakley Jee , Gunn Rose , Liu Shuling , Hatch Brigit A. , O’Leary Sean T. , Spina Christine I. , Allen Treasure , Cottrell Erika K. 
Published: October 2024

Objectives. To assess multilevel factors associated with variation in COVID-19 vaccination rates in a US network of community health centers. Methods. Using multilevel logistic regression with electronic health record data from ADVANCE (Accelerating Data Value Across a National Community Health Center Network; January 1, 2022–December 31, 2022), we assessed associations between health care delivery site–level (n = 1219) and patient-level (n = 1 864 007) characteristics and COVID-19 primary vaccine series uptake. Results. A total of 1 337 440 patients completed the COVID-19 primary vaccine series. Health care delivery site characteristics were significantly associated with lower series completion rates, including being located in non-Medicaid expansion states and isolated or rural communities and serving fewer patients. Patient characteristics associated with significantly lower likelihood of completing the vaccine series included being Black/African American or American Indian/Alaska Native (vs White), younger age, lower income, being uninsured or publicly insured (vs using private insurance), and having fewer visits. Conclusions. Both health care delivery site– and patient-level factors were significantly associated with lower COVID-19 vaccine uptake. Community health centers have been a critical resource for vaccination during the pandemic. ( Am J Public Health. 2024;114(11):1242–1251. https://doi.org/10.2105/AJPH.2024.307773 )
Prospective isolation of mouse and human hematopoietic stem cells using Plexin domain containing 2
Authors: Tanaka Yosuke , Kubota Yasushi , Lieberam Ivo , Kimura Takaharu , Barlow Jillian , Bramley Josh , Sakuma Chiaki , Shibata Takashi , Masataka Nakagawa , Kurosawa Yasunori , Maruyama Toshiaki , Yabushita Tomohiro , Okumura CJ , Akuta Teruo , Kent David , Jessell Thomas , Goyama Susumu , Kimura Shinya , Yamazaki Satoshi , Suda Toshio , Kitamura Toshio 
Published: October 2024

Abstract

Numerous strategies exist to isolate hematopoietic stem cells (HSCs) using complex combinations of markers and flow cytometry. However, robust identification of HSCs using imaging techniques is substantially more challenging which has prompted the recent development of HSC reporter mice. To date, none of the molecules used in these reporters have been useful for human HSC identification. Here we report that PLXDC2 is a useful marker for both mouse and human HSCs. Using a green fluorescent protein (GFP) knock-in at the Plxdc2 locus in mice (hereafter denoted as Plxdc2-GFP), we showed that Plxdc2-GFP is highly expressed in HSCs with 1 in 2.8 Plxdc2-GFP+CD150+ cells giving long-term multi-lineage reconstitution in transplantation. Moreover, we developed a novel human PLXDC2 antibody and showed that human PLXDC2+ HSCs have stronger long-term multilineage reconstitution ability compared with PLXDC2- HSCs in a xenograft model. Thus, our study identifies PLXDC2 as a highly relevant molecule in HSC identification, potentially allowing greater purity and live in vivo tracking of these cells.
Sputum and Blood Eosinophilia Level of Patient With Chroni̇c Obstructive Pulmonary Disease (Copd) Exacerbation in Hospitalized
Authors: gokturk ozge , suerdem mecıt , tulek baykal , kanat fikret , yormaz burcu , celik zeliha esin , gokturk kerim 
Published: October 2024

Abstract

Chronic obstructive pulmonary disease (COPD) is a common respiratory condition characterised by persistent airflow limitation and frequent exacerbations. In patients with COPD exacerbations, whether steroid therapy should be administered via inhalation or the systemic route remains unclear. To address this, we aimed to evaluate the response of sputum and blood eosinophil counts to systemic and inhaled steroids in hospitalised patients with COPD exacerbation. Our study included 58 patients hospitalised at a chest disease clinic for the treatment of COPD exacerbation. Upon admission, pre-induced sputum samples were collected. Patients were then randomly assigned to receive either intravenous methylprednisolone (40 mg/day) as a single daily dose in addition to standard exacerbation treatment (n=29) or budesonide (0.50 mg) via nebulisation at 12-h intervals for 7 days (n=29). Sputum haemograms and eosinophils were evaluated on the 14th and 45th days of treatment. In patients receiving intravenous steroid treatment, sputum eosinophil percentages were significantly reduced on days 14 (0.36±0.72) and 45 (0.28±0.53) compared to those at baseline (0.86±1.22) (p=0.041). Although decreases in the percentage of eosinophils in sputum, eosinophil count, and percentage in blood were observed on the 14th and 45th days compared to baseline values in patients receiving inhaled steroid treatment, these changes were not statistically significant (p>0.05). Adding systemic steroids to the treatment of severe COPD exacerbations is a rational approach. Further studies with longer follow-up periods are needed to determine the role of eosinophil levels in the blood and sputum as a marker for deciding on intravenous and inhaled steroid treatments.
Prevalence of Hypertension and Associated Risk Factors in Galkayo, Puntland- Somalia
Authors: Abdille Ahmed A. , Mohamed Sundus M. , Giama Abdulkadir M. , Bogale Kassawmar Angaw 
Published: October 2024

Abstract

Background
Hypertension is a significant global public health concern, yet research on its prevalence and associated risk factors in understudied regions in Somalia like Galkayo is very limited. This study aimed to investigate the prevalence of hypertension and its determinants among patients attending the Galkayo Medical Center (GMC).
Methods
A cross-sectional study was conducted from June to August 2023 at GMC. Participants (N = 382) were selected using systematic sampling and completed a questionnaire assessing demographics, clinical history, and lifestyle factors. Blood pressure measurements were obtained to confirm hypertension diagnosis. Data were analyzed using descriptive statistics, binary logistic regression, and multiple logistic regression.
Results
The study found a prevalence of 13.6% among participants. Older age, unemployment, and comorbidities are significantly associated with hypertension (p < 0.05). Multiple logistic regression identified younger age, employment status, and comorbidity as independent predictors of hypertension.
Conclusion
These findings underscore a considerable burden of hypertension among GMC Hospital attendees in Galkayo, Somalia. Efforts to address modifiable risk factors and enhance access to hypertension management services are crucial to mitigating the impact of this chronic condition on public health in the region. This study contributes valuable insights into the epidemiology of hypertension in a previously understudied area, informing targeted interventions to improve health outcomes and reduce the burden of hypertension in Galkayo and similar settings.
Public preferences for allocating health system resources in Canada: a systematic review
Authors: Ali Shehzad , Garaszczuk Roxanne , Moodie Jessica , Cipriano Lauren , Ghattas Lina , Ali Samya 
Published: October 2024

Abstract

Background

Conventional economic evaluations are based on the principle of health maximization. However, this approach does not consider societal preferences to prioritize health care for certain social groups and health conditions, and the public concern over health disparities. In recent years, equity-sensitive economic evaluation methods have been developed to incorporate societal concern over for health inequities. These methods use quantitative evidence based on preference elicitation exercises to inform allocation of health system resources.

Objective

To systematically review Canadian studies that quantify public preferences for allocating health care resource across sociodemographic groups and health conditions

Methods

Three electronic databases were searched: Ovid Embase, Ovid MEDLINE, and EBSCO EconLit. In addition, the reference lists of relevant papers were also scanned to detect any other suitable studies. The systematic review included studies meeting two criteria: studies that sampled Canadians and those where participants made decisions about resource allocation or responded to hypothetical scenarios about redistributing lifetime health. Two reviewers conducted screening, full-text review, and data extraction.

Results

Eight studies were identified that investigated public preferences for prioritizing health care in relation to age, income, disease rarity and baseline health. Age-related preferences favored children and younger patients over older patients. Aversion to socioeconomic-related health inequality was heterogeneous and was associated with respondent characteristics. No clear preference was found for treatments for rare diseases over common conditions, or for baseline quality of life and life expectancy. Two studies exposed participants to moral reasoning exercises that resulted in slightly lower level of prioritization of specific conditions or groups.

Conclusion

There is clear evidence to prioritize health care resources for children and younger patients over older patients. There is limited or no Canadian evidence on societal values on tackling health inequity related to socioeconomic status, sex/gender, race/ethnicity and other social determinants of health. Future research can help bridge this gap.
Quantitative analysis of microplastics in water by Raman spectroscopy: influence of microplastic concentration on Raman scattering intensities
Authors: Pyo Sung Gyu , Jung Eun Su , Choe Jin Hyun , Kim Jin Seok , Ahn Da Won , Yoo JinUk , Choi Tae Min 
Published: October 2024

Abstract

In this study, quantitative Raman scattering analysis was employed for the direct detection of microplastics in water. Raman intensities varied according to the change in the concentration of microplastics in water. Microplastic samples consisted of 40–100 μm polyvinyl chloride (PVC) spherical particles; 40–48 μm polyethylene (PE) spherical particles; 0.1–1.0 wt% of each microplastic sample was dispersed in de-ionized water. In the case of PE particles in water, a peak corresponding to the twisting of the CH2 bond was observed at 1295 cm-1, and the area integrated intensity ratio with a H2O broad peak at 3,400 cm-1 was observed. The peak area ratio increased linearly with the PE particle concentration, and the linear equation and R2 value were y = 0.22797x+0.0125 and 0.92, respectively. In the case of the PVC particles in water, the peak belonging to the stretching vibration of the C–Cl bond appeared at 637 cm-1, which linearly increased in intensity when the peak area ratio with H2O was observed. The linear expression and R2 value were y = 0.37704x-0.01821 and 0.88, respectively. The results confirmed that the dispersed microplastic particles of PE and PVC in water (up to ~0.1 wt%, and up to 0.22 μm particles) can be directly detected by the Raman scattering analysis method.
Impact of metabolic rewiring by KRAS mutations on plasma lipidome profiling in patients with advanced solid tumors
Authors: Alonso-Villaverde Carlos , Ramos Javier , Fernández-Sénder Laura , Villuendas Óscar , Valentí Vicente 
Published: October 2024

Abstract

Purpose: To find differences in plasma lipidomic signatures between patients with advanced solid tumors harboring KRAS mutations and those with KRAS wild-type tumors.
Methods: Gas chromatography coupled to quadrupole time-of-flight mass spectrometry was used to determine polar and neutral lipid levels. Data were normalized using Probabilistic Quotient Normalization. Somatic KRAS mutational status was assessed on tumor tissue. Metaboanalyst 5.0 was used to perform univariate, multivariate, and supervised analyses.
Results: Thirty-seven patients were included in the study, 10 of them (27%) with KRAS-mutated tumors. The univariate analysis on polar lipids showed that patients with KRAS-mutated tumors had significantly higher levels of various lysophosphocholines (LPC) [sn1:(15:0), (18: 0), (19:0), (20:0); sn2: (14:0), (15:0), (16:0), (18:2), (19:0), (20:5)]. Levels of unsaturated fatty acids (FA) 1,13-eicosadienoic acid, adrenal acid, eicosenoic acid, SDA-iso1, and w6–DPA were significantly lower in the mutated group. Also, levels of the oxidized lipids (oxylipins) 9,10-EpOME(12), epoxy-stearic acid, x -OxoODE-iso1, 12-HETE, 15-HETE, x-HETE-iso1, x-oxoODE-iso1, were significantly lower in the group with KRAS mutation. The PLS-DA analysis also discriminated between these values between both groups. The ROC curves showed that the ratio of unsaturated FA to lysophosphocholines could predict KRAS mutation status (AUC=0.86 for the ratio 11,13-eicosadienoic/LPC sn2-20:0).
Conclusion: Patients with KRAS-mutated tumors have increased plasma levels of sn2-LPC and sn1-LPC. Suggesting enhanced phospholipase 1 and 2 activity. Lower plasma levels of unsaturated FA and oxylipins in KRAS-mutant tumors suggest an enhanced consumption of FA through beta-oxidation. The ratio unsaturated FA/LPC may serve as a biomarker for KRAS mutational status prediction.