bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethnographic Study Found School Library is a Safe Refuge of Solitude for French Urban Middle School Students
Authors: Shen Lisa 
Published: September 2024

A Review of:
Joing, I. (2023). The school library: An important place for adolescents’ well-being. An ethnographic experience in a French middle school. Journal of Library Administration, 63(6), 777-796. https://doi.org/10.1080/01930826.2023.2240192
Objective – To understand the role of school libraries in middle school students’ well-being.
Design – Ethnographic study consisting of overt participant observation, semi-structured interviews, and a written questionnaire.
Setting – An urban middle school in northern France between November 2017 and April 2018.
Subjects –Students from 10 to 15 years of age and selected school personnel.
Methods – Students from three randomly selected classes were invited to complete the questionnaire, and quantifiable responses were summarized using descriptive statistics. Other materials collected during the five-month study period, including the researcher’s field journal, interview transcripts, and qualitative questionnaire responses, were analyzed using grounded theory-informed open, axial, and selective coding to discern students’ perception of the library.
Main Results – The majority of the 95 students who completed the questionnaire viewed the library as a safe place associated with positive school experiences. However, these favorable impressions gradually decreased as students progressed in their studies, with senior (fourth-year) respondents reporting the lowest positive-to-negative experience ratio, at 1.1 to 1. Thematic clusters that emerged from coding of the rest of study materials further supported these findings, showing that students perceived the library to be both (a) a physical shelter from harsh winter elements during recess or lunch, and (b) a psychological refuge for solitude and peace from negative peer interactions. Nonetheless, (c) limited and unreliable library hours and (d) restrictive rules concerning noise and space access appeared to erode these positive associations over time. Senior students also expressed (e) the desire for more library or general school spaces dedicated to group work.
Conclusion – Findings from this ethnographic study highlighted different ways library space contributed to students’ sense of well-being. The study also uncovered some shortcomings in space management that contributed to students’ declining library use and positive perception over the course of middle school. The researcher recommended extending library hours and expanding the diversity of library activities to ensure the space would serve as a welcoming environment not only for students seeking solitude, but also for those desiring more peer collaborations and social connections.
Four decades in the vineyard: the impact of climate change on grapevine phenology and wine quality in northern Italy
Authors: Faralli Michele , Mallucci Stefano , Bignardi Alessandro , Varner Mauro , Bertamini Massimo 
Published: September 2024

The wine sector, among the most profitable agricultural segments, has been markedly affected by the ongoing climate change impacts, such as warmer climate conditions with higher frequency of extreme temperatures and a trend of decreasing precipitation. All this results in higher evaporative demand and therefore higher occurrence of water stress events leading to advancement of temperature-sensitive phenological stages (e.g., budburst and ripening). Such negative effects eventually affect berry development and quality, especially in historically valuable viticultural areas, forcing winegrowers to work within a compressed harvest period to maintain wine typicity. In this work we examined the relationship between environmental variables (air and soil temperature, relative humidity, precipitation, and solar radiation), phenology, berry, and wine quality for the two varieties (Chardonnay and Teroldego) in Trentino Alto-Adige/South Tyrol (Italy) over 36 years. Huglin Index (a bioclimatic heat index), growing degree days (measure of heat accumulation), and overall mean temperature showed linear increase (p < 0.001) in the last years, while no variations were recorded for precipitations. Despite no major effects being observed for phenological interval lengths, the onset of most of the phenological stages for both varieties had significantly (p < 0.001) advanced. However, i) early budburst pushed the budburst-flowering interphase by -1.2 days every two years toward putative colder periods with increased late frost probability and potential slower phenological progression towards flowering, and ii) early veraison shifted the veraison-ripening interphase by 0.25 day per year into warmer periods that oppositely impose faster phenological advancement. Hence, a substantial equilibrium in the seasonal growing length over years was maintained. Potential carry-over effects from the previous season were observed, particularly associated with heat requirements to unlock early phenological events, raising additional concerns on the additive effects of climate change to viticulture. Generally, white wine quality increased (p < 0.05) over the years, while red and sparkling wines remained unaffected. This was putatively related to accurate harvest date decision-making dictated by berry quality parameters: sugar-to-acidity ratio for Chardonnay and bunch sanitary status for Teroldego. Overall, this work provides evidence of the dynamics involved in climate change, and, to our knowledge, its overlooked effects on viticulture, thus providing new insights that can contribute to further developing adaptive strategies.
Stoicism 'à la mode': Senecan Ethics in Roger Bacon’s 'Moralis philosophia'
Authors: Colish Marcia 
Published: September 2024

While recent scholarship accents early Franciscans’ use of Greek and Greco-Arabic sources in their ethics, Roger Bacon’s appeal to Stoic ethics via Seneca in his Moralis philosophia, the last book of his Opus maius, has not been given its due. Bacon’s citation of Seneca’s dialogues privileges De ira and works he associates with it. Placing Bacon’s ethics in the context of classical and Christian traditions on anger, this paper argues that Bacon uses Seneca to undermine the arguments for righteous anger in both these traditions, specifically those validated by his Franciscan contemporary John of La Rochelle. Bacon’s alternative addresses ethical and political concerns he shares with his dedicatee, Pope Clement IV, and with Franciscan confrères committed to popular preaching and the apostolate to non-Christians. As such, Bacon’s Stoic ethics à la mode needs clearer recognition in the ongoing reinterpretation of thirteenth-century Franciscan thought.
Evidence of Simple Harmonic Motion in the Settingof Elementary Electric Charge: A Review ofHistorical Data and Implications for Future Research
Authors: Williams Lamont 
Published: September 2024

Abstract

In many early studies of the value of elementary electric charge (e), experimentalists identified what appeared to be substantial discrepancies among results. Some discrepancies were explained; some were not. This investigation provides evidence suggesting that some discrepancies among experimental findings for the value of e may have been the result of the electromagnetic field between interacting particles behaving somewhat like a spring undergoing simple harmonic motion. Here, the standard value of e is associated with the equilibrium position of the field and the other values are associated with displacement from that position. This would have led to higher values of e in some cases and lower values in others, consistent with the experimental findings. Implications for the spatiotemporal nature of electrons in materials, fine-structure constant, and Landau pole are discussed.
Lynronne antimicrobial peptides with terminal D amino acid enantiomers synergize with bedaquiline against Mycobacterium tuberculosis
Authors: Hingley-Wilson Suzie , Xu Ye , Oyama Linda , Akwani Winifred , Casey Rosalyn , Huws Sharon , McFadden Johnjoe 
Published: September 2024

Abstract

Tuberculosis (TB) treatment is challenging due to prolonged chemotherapy and rising multidrug resistance. Here, we investigated the antimicrobial properties of the antimicrobial peptides (AMPs) lynronne (LYN)-1, -2 and -3, both in their natural form or with terminal D-enantiomers, alongside their synergistic effects with common TB drugs. Notably, D-enantiomer replacement improves LYNs’ stability and activity. Moreover, lynronne-1D (LYN1D) and lynronne-3D (LYN3D) is synergistic with bedaquiline (BDQ), significantly reducing the bactericidal concentrations of LYN1D, LYN3D and BDQ. Transcriptome studies demonstrated that this synergy is associated with perturbation of multiple pathways, including negative transcriptional regulators, lipid transporters, arabinogalactan biosynthesis, and the oxidative phosphorylation pathway. Furthermore, cellular morphology changes and ATP reduction suggested a synergistic model where the combination of LYNDs with BDQ simultaneously targets cell membrane lipids and energy production, resulting in the eradication of Mycobacterium tuberculosis. This synergistic combination of BDQ with D-enantiomers AMPs offers a novel TB treatment strategy, and a model for developing synergistic drug combinations to tackle other infectious diseases.
Effect of Selected Variables on Child Mortality in Ethiopia using 2019 EMNDHS: Application of Zero Inflated Negative Binomial Mixed Effect Regression Model
Authors: Asmare Adane , Addis Berhanie 
Published: September 2024

Abstract

. Approximately 6.3 million under 5 age of children were died in 2013. An estimate of 2.4 million child die before their first month of birth. Struggling for the lives of new-born children must be the global concern. Under five child mortality rates was decreased from 32% in 1990 to 18% in developed country but it was decreased with lower rates in developing countries especially in Sub Sharan African and southern Asian countries. maternal and household characteristics such as place of child residence in rural areas, poor wealth index of household and uneducated mothers had the higher risk deaths of under-five child mortality rate. The data source for this analysis was 2019 EMDHS data. To analyse the effects of selected variables on under five child mortality, zero inflated negative binomial mixed effect regression model were appropriate. Goodness of fit model were based on AIC value and smaller AIC values were good fitted model. In This investigation the variables age of mother, age of mother at 1st birth, mother’s education level, types of cooking fuel, number of living children and types of birth were statistically significant factor for non-zero death of under-five child mortality in Ethiopia.
SLITRK2 as a Prognostic and Immunological Biomarker in Gastric Cancer
Authors: zhu huiqiong , Xiong Hailin , Guo Xuli , Liao Haojie , Zhang Shuyi 
Published: September 2024

Abstract

Background
SLIT and NTRK-like protein 2 (SLITRK2) encodes a transmembrane protein that regulates neurite outgrowth and promote synaptogenesis. Some studies have demonstrated that SLITRK2 overexpressed in glioma. But the expression pattern, prognostic value, and immunologic function of SLITRK2 in tumors remains unknown.
Methods
The expression pattern of SLITRK2 among pan-cancers were examined through different databases, including the Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx). We analyzed the SLITRK2 expression in different stages of cancers. The relationship between SLITRK2 expression and clinical outcomes was conducted by Kaplan-Meier method. Moreover, the correlations among SLITRK2 expression, immune cell infiltration, immunomodulatory related genes, tumor mutation burden (TMB), microsatellite instability (MSI) were evaluated as well. The relationship between SLITRK2 expression and crucial genes mutations was also illustrated. By using tissue multi-array (TMA), the expression of SLITRK2 in 89 paired gastric cancer tissues was investigated.
Results
Our study indicated that SLITRK2 expression varied across cancers. Elevated SLITRK2 expression was positively related to advanced tumor stage, poor overall survival(OS) and reduced disease-free survival (DFS). It also verified that SLITRK2 expression level was correlated with immune cell infiltration, expression of immunomodulators, TMB, MSI in certain cancer types. In stomach adenocarcinoma (STAD), SLITRK2 expression and clinicopathological features revealed that high expressing level of SLITRK2 associated with poorer outcomes. Importantly, based on tissue TMA data, SLITRK2 expression level was positively associated with differentiation, lymph node metastasis, AJCC stage, TNM stage, and poor survival outcome in GC patients.
Conclusion
Our findings provided that SLITRK2 may function as a potential biomarker and oncogene in pan-cancer. In addition, SLITRK2 was correlated with immune cell infiltration in pan-cancer, providing a potential drug target, especially in STAD.
Assessment of the circular economy indicators in the EU Member States
Authors: Remeikiene Rita , Gaspareniene Ligita , Bankauskiene Justina 
Published: September 2024

Abstract

The circular economy principles are believed to contribute to waste reduction, pollution and climate change prevention, conservation of resources and security of their supply, and economic resilience. Therefore, it is extremely important not only to implement the principles of the circular economy, but also to properly assess their impact, so that stakeholders can make reasonable decisions and develop effective strategies to promote the green transition. Nevertheless, despite a wealth of literature to discuss the circular economy indicators, a comprehensive assessment method has not yet been developed. The research problem is formulated as a question: what indicators can be used to assess the level of the circular economy in national economies? The major purpose of the research is to empirically assess the level of the circular economy in the EU Member States. The research methods include literature analysis, systematisation and summarisation; secondary data analysis; weight estimation methods: the Entropy and expert evaluation; mutiple-criteria decision analysis: the PROMETHEE, SAW and TOPSIS methods.
Unstable Foveation Impairs Both Reading and Tracking: Insights and Implications for the Diagnosis and Intervention of Reading Difficulties
Authors: Chamani Niloufar , Schmid Michael Christoph , Rima Samy 
Published: September 2024

Abstract

Foveation, the ability to focus on a point for clear vision, is crucial for reading smoothly and tracking moving objects. Research shows that unstable foveation disrupts reading by causing more frequent eye movements. However, it's unclear if this also affects smooth tracking of moving targets in slow readers. This study therefore investigates the link between foveation during reading and the tracking moving targets, in a large group of participants displaying variable reading speeds. Our analysis shows that slower readers have more intrusive fixational eye movements characterized by greater spatial and temporal variability during reading. Additionally, these readers display less efficient tracking of moving targets. Interestingly, the frequency and spatial variability of catch-up saccades during object tracking correlates with fixational eye movement rates and spatial variability during reading. Our findings thus demonstrate that poor foveation stability in slow readers also affects other eye movement activities, such as during object tracking. We conclude with a discussion on shared neural mechanisms of foveal stabilization that may be altered under conditions of reading impairment. Better knowledge of these mechanisms could help the development of diagnostic tools and targeted interventions to improve reading and tracking for individuals with foveation limitations.
Spectral variability analysis Lupinus Mutabilis Sweet under nanofertilizers and chelates application through spectroscopy and Unmanned Aerial Vehicles (UAV) multispectral images.
Authors: Sinde-González Izar , Murgueitio Erika , Falconí César , Docampo Mariluz Gil , Toulkeridis Theofilos 
Published: September 2024

Abstract

Lupine is an Andean legume that has gained importance in Ecuador due to its protein content in the grain. However, in recent times the production of this crop has been affected by inadequate nutritional management. In order to avoid such circumstances, the current study spectrally analyzed lupine cultivation by the effect of the application of nanofertilizers and Fe and Zn chelates, within two controlled trials, using a radiometer spectrum, an active crop sensor and a multispectral sensor mounted on a UAV. Vegetation indices were generated and statistically analyzed using an ANOVA and Tukey tests. In the field trial, the treatments lacked to indicate significant improvements, while in the greenhouse trial, the nanofertilizer treatments indicated better results compared to the control ones. Furthermore, the chelate treatment presented a certain degree of toxicity for the plant.
Suxiao jiuxin pill protects endothelial cells from oxidative stress-induced apoptosis via Nrf2/HO-1 pathway
Authors: Fan Zhijuan , Tian Yaqiong , Liu Bojiang , Ning Meng , Wei Jin , Zeng Lingfang , zhao yue , Zhang Min 
Published: September 2024

Abstract

Abstract

Background

Reactive oxygen species (ROS) are implicated in the pathogenesis of cardiovascular diseases (CVDs). Suxiao Jiuxin Pill (SX), a traditional Chinese medicine, has emerged as a promising herbal remedy with demonstrated efficacy in ameliorating cardiovascular pathology and improving clinical outcomes. Although SX exhibits significant antioxidant activities, the underlying mechanism remains unclear.

Methods

We utilized a mouse endothelial cell line, C166, to investigate the role of SX in regulation of oxidative stress. Hydrogen peroxide (H2O2) was employed to induce cell apoptosis. Cells were sequentially treated with SX, specific inhibitors, and H2O2. RT-qPCR and Western blot analyses were performed to evaluate changes at the mRNA and protein levels, respectively.

Results

SX demonstrated protective effects against H2O2-induced apoptosis in endothelial cells (ECs). Both the mRNA and protein levels of heme oxygenase-1 (HO-1) increased in response to SX treatment. Importantly, the protective role of SX in ECs was abolished by the HO-1 inhibitor Zinc protoporphyrin IX (ZnPP). Treatment with actinomycin D and cycloheximide revealed that SX upregulated HO-1 expression via de novo synthesis, and Nrf2 was verified as the main mediator. Furthermore, degradation of Nrf2 by its specific inhibitor, brusatol, reversed the protective effects of SX on ECs under oxidative stress.

Conclusion

SX plays a crucial role in protecting ECs from oxidative stress-induced apoptosis through activation of the Nrf2/HO-1 pathway. The protective effect of SX is dependent on HO-1 function, and inhibition of either Nrf2 or HO-1 effectively blocks the protective effect of SX.
Design and motion simulation analysis of tuna sorting device control system
Authors: SHEN Yingyi , LI Zhenhua , LI Xinyang 
Published: September 2024

Abstract

In this paper, first of all, the use of SOLIDWORKS software for tuna sorting device for the preliminary three-dimensional design, the use of four suspended load cells for tuna weighing work, the choice of Siemens S7-200 smart series of PLC tuna sorting device system control, and through EDEM simulation simulate tuna in the sorting device on the transmission movement, with the amount of fish, conveyor belt speed, partition angle as the test factors for the sorting efficiency based on Box-Behnken design response surface test, select the range of the amount of fish for the 0.5 ~ 1.5 / s, the range of conveyor belt speed for the 0.2 ~ 0.5m / s, the rotation angle of the partition for the 15 ~ 45 °, through the orthogonal experiments ANOVA as well as response surface analysis to conclude that The efficiency can reach more than 95 percent at this time, when the fish feeding volume is 0.5 fish/s, the conveyor belt speed is 0.5m/s, and the spacer rotation angle is 41°. Additionally, A force analysis of the device's sorting mechanism revealed that a 0.6 m partition would optimize tuna sorting efficiency.
A Multi-Modal Sarcasm Detection Model Based onCue Learning
Authors: Lu Ming , Dong Zhiqiang , Zhang Litian , Guo Ziming , Zhang Xiaoming 
Published: September 2024

Abstract

The rapid proliferation of internet data, particularly through social media, has amplified the need for effective sentiment analysis, including the complex task of sarcasm detection. This paper presents a novel multi-modal sarcasm detection model leveraging cue learning techniques to address the challenges posed by data scarcity, especially in low-resource languages. The proposed model builds upon the CLIP architecture, integrating text and image modalities to co-learn sarcasm cues. The methodology encompasses discrete prompt generation, learnable continuous vectors, and multi-modal fusion to enhance detection accuracy. The multi-modal fusion process demonstrates a symmetric integration of text and image data, leading to improved performance. Experimental results on the Twitter Multi-modal Sarcasm Detection Dataset (MSD) demonstrate significant performance improvements over traditional models, highlighting the model's robustness and adaptability in small-sample scenarios. This research contributes a practical solution for nuanced sentiment analysis, paving the way for advanced applications in public opinion monitoring and AI-driven decision-making processes.