bluuebunny/crossref_metadata_2025_split huggingface dataset:
Templating synthesis of Fe2O3 hollow spheres modified with Ag nanoparticles as superior anode for lithium ion batteries
Authors: Lin Xiaoping , Zhang Jianmin , Tong Xiaobin , Li Han , Pan Xi , Ning Peigong , Li Qiuhong 
Published: August 2017

AbstractAg-Fe2O3 hollow spheres are synthesized by using Ag@C core-shell matrix as sacrificial templates. The morphologies and structures of the as-prepared samples are characterized by scanning electron microscopy, X-ray powder diffraction energy dispersive, transmission electron microscopy and high resolution transmission electron microscopy. In contrast to Fe2O3 hollow spheres, Ag-Fe2O3 hollow spheres exhibit much higher electrochemical performances. The Ag-Fe2O3 composites exhibit an initial discharge capacity of 1030.9 mA h g−1 and retain a high capacity of 953.2 mA h g−1 at a current density of 100 mA g−1 after 200 cycles. Furthermore, Ag-Fe2O3 electrode can maintain a stable capacity of 678 mA h g−1 at 1 A g−1 after 250 cycles. Rate performance of Ag-Fe2O3 electrode exhibits a high capacity of 650.8 mA h g−1 even at 5 A g−1. These excellent performances can be attributed to the decoration of Ag particles which will enhance conductivity and accelerate electrochemical reaction kinetics. Moreover, the hollow structure and the constructing particles with nanosize will benefit to accommodate huge volume change and stabilize the structure.
Volumetric Optoacoustic Temperature Mapping in Photothermal Therapy
Authors: Landa Francisco Javier Oyaga , Deán-Ben Xosé Luís , Sroka Ronald , Razansky Daniel 
Published: August 2017

AbstractPhotothermal therapy and ablation are commonplace medical procedures employed for treatment of tumors, vascular and brain abnormalities as well as other disorders that require selective destruction of tissues. Yet, accurate mapping of the dynamic temperature field distribution in the treated region represents an unmet clinical need, strongly affecting the clinical outcome of these interventions. We introduce a fast three-dimensional temperature mapping method based on real-time optoacoustic sensing of the treated region coupled with a thermal-diffusion-based model of heat distribution in tissues. Deviations of the optoacoustic temperature readings provided at 40  ms intervals remained below 10% in tissue-mimicking phantom experiments for temperature elevations above 3 °C, as validated by simultaneous thermocouple measurements. Performance of the new method to dynamically estimate the volumetric temperature distribution was further showcased in post-mortem mouse imaging experiments. The newly discovered capacity to non-invasively measure the temperature map in an entire treated volume with both high spatial and temporal resolutions holds potential for improving safety and efficacy of light-based therapeutic interventions.
Calorie restriction effects on circadian rhythms in gene expression are sex dependent
Authors: Astafev Artem A. , Patel Sonal A. , Kondratov Roman V. 
Published: August 2017

AbstractThe rhythms in the expression of circadian clock genes are affected by calorie restriction (CR), a dietary paradigm known to increase lifespan. Many physiological effects of CR differ between males and females; here we investigated if the sex of animals affects the CR induced changes in the circadian rhythms. The liver expression of some circadian clock genes such as Bmal1 and three Periods (Per1, Per2 and Per3) and the effect of CR on the expression of these genes were sex independent, while the expression of Rev-Erb alpha, Ror gamma and both Cryptochome (Cry1 and Cry2) genes was different between males and females. The effect of CR on Rev-Erb alpha, Ror gamma and Cry1 gene expression was sex dependent. The expression and the effects of CR were sex-specific for several genes previously reported to be regulated by CR: Fmo3, Mup4, Serpina12 and Cyp4a12, while the expression of Cyp4a14a was sex independent. IGF signaling plays an important role in aging and CR effects. Igf-1 expression is regulated by CR and by the circadian clock, we found that rhythms in Igf-1 expression have sexual dimorphism. Our data provide molecular evidence that the sex of animals is an important modulator of circadian rhythms in gene expression and their response to CR.
Intravenous Fluid Challenge Decreases Intracellular Volume: A Bioimpedance Spectroscopy-Based Crossover Study in Healthy Volunteers
Authors: Ernstbrunner Matthäus , Kabon Barbara , Zotti Oliver , Zeitlinger Markus , Berner Carolin , Hinterholzer Georg , Säemann Marcus , Frommlet Florian , Fleischmann Edith , Hecking Manfred 
Published: August 2017

AbstractThe effects of intravenous fluid therapy on fluid compartments and hemodynamics of the human body remain enigmatic. We therefore tested the efficacy of bioimpedance spectroscopy in a crossover study, where 15 males received 0.5 ml/kg/min ELO-MEL-isoton (osmolarity = 302 mosmol/l) during 60 minutes, or nothing at all. In group “Fluid”, fluid load increased from −0.2 ± 1.0 l extracellular volume at baseline to its maximum of 1.0 ± 0.9 l in minute 70, and remained continuously elevated throughout minute 300. In group “Zero”, fluid load decreased from 0.5 ± 1.1 l at baseline to its minimum of −1.1 ± 1.1 l in minute 300. In group “Fluid”, intracellular volume decreased from 26.8 ± 3.9 l at baseline to its minimum of 26.0 ± 3.9 l in minute 70, and remained continuously decreased throughout minute 300. In group “Zero”, intracellular volume increased from 26.5 ± 3.8 l at baseline to its maximum of 27.1 ± 3.9 l in minute 120, and decreased thereafter. In group “Fluid” compared to “Zero”, systolic blood pressure was significantly higher, from minute 50–90. In conclusion, intravenous fluid therapy caused a clinically meaningful, sustained increase in fluid load, and a decrease in intracellular volume. These data raise interest in studying fluid administration by the gastrointestinal route, perhaps even when managing critical illness.
Acupuncture for behavioral changes of experimental depressive disorder: a systematic review and meta-analysis
Authors: Kou Ren-zhong , Chen Hong , Yu Mei-ling , Xu Tian-cheng , Fu Shu-ping , Lu Sheng-feng 
Published: August 2017

AbstractAcupuncture is considered to be a promising alternative therapy for depression. Nevertheless, up to now, it remains controversial on the effects exerted by acupuncture on behavioral changes in depression models. Consequently, it’s necessary to develop a systematic review and meta-analysis to assess the effect of acupuncture for model rats of depression. Ultimately, 90 studies involving 1861 models were identified. Behavioral indicators including the number of crossings (NC) and the number of rearings (NR) in open field test (OFT), the capacity of sucrose intake (CSI) and the rate of sucrose intake (RSI) in sucrose intake test (SIT), final weight (FW) and gain weight (GW) were employed as main outcomes in depression model rats. The pooled results showed that acupuncture had not less effect than western medicine on improving NC, NR, FW, GW, RSI (P > 0.05). However, the CSI improvement was poorer compared with west medicine (P < 0.05). In conclusion, acupuncture has not less effect on behavior changes than western medicine, including improving NC, NR, RSI, FW and GW in depression models.
Differential changes in the adenoids and tonsils in Japanese children and teenagers: a cross-sectional study
Authors: Manabe Asuka , Ishida Takayoshi , Yoon Hyung Sik , Yang Shin-Sheng , Kanda Eiichiro , Ono Takashi 
Published: August 2017

AbstractWhen adenoids (Ad) and tonsils (Tn) become hypertrophied, craniofacial and general body growth is affected. However, there are no objective explicit criteria for evaluating the size of the Ad and Tn, and their respective growth patterns remain unclear. This study determined the average proportions of the Ad and Tn sizes to the upper airway area at various developmental stages in Japanese individuals. Lateral cephalometric radiographs were obtained from 300 Japanese children and teenagers (150 boys and 150 girls, aged 6–20 years), and the respective proportions of Ad to the nasopharynx (Ad/Np) and Tn to the oropharynx (Tn/Op) in the upper airway were determined. Average and standard deviation (SD) were calculated for each of the 5 age groups: lower primary school, upper primary school, junior high school, senior high school, and young adults. We investigated the correlation between age and growth patterns of Ad and Tn, and determined the average Ad/Np and Tn/Op. There was an age-related decrease in Ad and Tn size, and a significant positive correlation between Ad/Np and Tn/Op values in the upper primary school group. Both Ad/Np and Tn/Op decrease as individuals approach adulthood. However, the growth patterns of the Ad/Np and Tn/Op differ from each other.
Enhanced spectral profile in the study of Doppler-broadened Rydberg ensembles
Authors: Wu Bo-Han , Chuang Ya-Wen , Chen Yi-Hsin , Yu Jr-Chiun , Chang Ming-Shien , Yu Ite A. 
Published: August 2017

AbstractCombination of the electromagnetically-induced-transparency (EIT) effect and Rydberg-state atoms has attracted great attention recently due to its potential application in the photon-photon interaction or qubit operation. In this work, we studied the Rydberg-EIT spectra with room-temperature 87Rb atoms. Spectroscopic data under various experimental parameters all showed that the contrast of EIT transparency as a function of the probe field intensity is initially enhanced, reaches a maximum value and then decays gradually. The contrast of spectral profile at the optimum probe field intensity is enhanced by 2–4 times as compared with that at weakest intensity. Moreover, the signal-to-noise ratio of the spectrum can potentially be improved by 1 to 2 orders of magnitude. We provided a theoretical model to explain this behavior and clarified its underlying mechanism. Our work overcomes the obstacle of weak signal in the Rydberg-EIT spectrum caused by an apparent relaxation rate of the Rydberg polariton and weak coupling transition strength, and provides the useful knowledge for the Rydberg-EIT study.
The synergy between natural polyphenol-inspired catechol moieties and plant protein-derived bio-adhesive enhances the wet bonding strength
Authors: Wang Zhong , Zhao Shujun , Song Ruyuan , Zhang Wei , Zhang Shifeng , Li Jianzhang 
Published: August 2017

AbstractNovel soybean meal-based biomimetic (STP) adhesives were fabricated via soybean meal (SM) and enhanced by tannic acid (TA) and polyetheylenimine (PEI) (TAPI) co-crosslinking network based on natural polyphenol-inspired chemistry. The multiple physico-chemical interactions (including intermolecular H-bonding and covalent bonding) between the TAPI co-crosslinking system and SM matrices were examined by the Fourier transform infrared spectroscopy, solid-state 13C nuclear magnetic resonance, X-ray diffraction, thermogravimetric analysis, and scanning electron microscopy. The results showed that a dense, robust, and water-resistant adhesive layer was constructed between network-bound catechol moieties in the TAPI and SM system, endowing the STP ﻿adhesive﻿ with high wet bonding strength for plywood. As expected, TAPI-modified SM adhesives showed a 156.1% increase in wet bonding strength compared to the control SM adhesive. The adhesion meets standard requirements for interior-use plywood. Both the solid content and residual mass analysis also confirmed that the enhancement in the STP adhesive was attributable to the network crosslinking density and stiffness after integrating the TAPI system. Moreover, the thermal stability of the resultant STP adhesive exhibited a significant improvement. The proposed STP adhesive may be a promising cost-effective and wet-resistant bio-adhesive for the application in the wood composites industry.
Nanoscale 2.5-dimensional surface patterning with plasmonic lithography
Authors: Jung Howon , Park Changhoon , Oh Seonghyeon , Hahn Jae W. 
Published: August 2017

AbstractWe report an extension of plasmonic lithography to nanoscale 2.5-dimensional (2.5D) surface patterning. To obtain the impulse response of a plasmonic lithography system, we described the field distribution of a point dipole source generated by a metallic ridge aperture with a theoretical model using the concepts of quasi-spherical waves and surface plasmon–polaritons. We performed deconvolution to construct an exposure map of a target shape for patterning. For practical applications, we fabricated several nanoscale and microscale structures, such as a cone, microlens array, nanoneedle, and a multiscale structure using the plasmonic lithography system. We verified the possibility of applying plasmonic lithography to multiscale structuring from a few tens of nanometres to a few micrometres in the lateral dimension. We obtained a root-mean-square error of 4.7 nm between the target shape and the patterned shape, and a surface roughness of 11.5 nm.
Biased visuospatial perception in complex regional pain syndrome
Authors: Filbrich Lieve , Alamia Andrea , Verfaille Charlotte , Berquin Anne , Barbier Olivier , Libouton Xavier , Fraselle Virginie , Mouraux Dominique , Legrain Valéry 
Published: August 2017

AbstractComplex regional pain syndrome (CRPS) is a chronic pain condition associating sensory, motor, trophic and autonomic symptoms in one limb. Cognitive difficulties have also been reported, affecting the patients’ ability to mentally represent, perceive and use their affected limb. However, the nature of these deficits is still a matter of debate. Recent studies suggest that cognitive deficits are limited to body-related information and body perception, while not extending to external space. Here we challenge that statement, by using temporal order judgment (TOJ) tasks with tactile (i.e. body) or visual (i.e. extra-body) stimuli in patients with upper-limb CRPS. TOJ tasks allow characterizing cognitive biases to the advantage of one of the two sides of space. While the tactile TOJ tasks did not show any significant results, significant cognitive biases were observed in the visual TOJ tasks, affecting mostly the perception of visual stimuli occurring in the immediate vicinity of the affected limb. Our results clearly demonstrate the presence of visuospatial deficits in CRPS, corroborating the cortical contribution to the CRPS pathophysiology, and supporting the utility of developing rehabilitation techniques modifying visuospatial abilities to treat chronic pain.
Electrically driven, highly efficient three-dimensional GaN-based light emitting diodes fabricated by self-aligned twofold epitaxial lateral overgrowth
Authors: Yoo Yang-Seok , Song Hyun Gyu , Jang Min-Ho , Lee Sang-Won , Cho Yong-Hoon 
Published: August 2017

AbstractImprovements in the overall efficiency and significant reduction in the efficiency droop are observed in three-dimensional (3D) GaN truncated pyramid structures fabricated with air void and a SiO2 layer. This 3D structure was fabricated using a self-aligned twofold epitaxial lateral overgrowth technique, which improved both the internal quantum efficiency and the light extraction efficiency. In addition, a reduced leakage current was observed due to the effective suppression of threading dislocations. While this study focuses primarily on the blue emission wavelength region, this approach can also be applied to overcome the efficiency degradation problem in the ultraviolet, green, and red emission regions.
A cross-sectional observational study on allergen-specific IgE positivity in a southeast coastal versus a southwest inland region of China
Authors: Zeng Guangqiao , Luo Wenting , Wu Zehong , Li Ling , Zheng Peiyan , Huang Huimin , Wei Nili , Luo Jiaying , Sun Baoqing , Liu Yong 
Published: August 2017

AbstractFew studies addressed trans-regional differences in allergen sensitization between areas within a similar latitudinal range but with distinct geomorphological features. We investigated specific IgE (sIgE) positivity to common allergens in populations from two southern China provinces. Using a uniformed protocol, serum samples were collected from 2778 subjects with suspected atopy in coastal Guangdong and inland Yunnan. The overall prevalence of sIgE positivity were 57.8% (95% CI: 56.0%, 59.6%) from Guangdong vs 60.9% (95% CI: 59.1%, 62.7%) from Yunnan. House dust mite (d1) was the most common allergen in both regions. Among d1-sensitized subjects, only 35.7% (208/583) in Guangdong and 22.9% (147/642) in Yunnan tested positive for d1 alone. Among those poly-sensitized d1-positive subjects, cockroach was the most common co-sensitizing aeroallergen. 41.9% of the d1-sensitized Guangdong subjects showed high-class sIgE reactivity (≥class 4), in contrast to a very low percentage of such reactivity in Yunnan. However, 36.3% of d1-sensitized subjects in Yunnan were concomitantly positive for tree pollen mix. Surprisingly, Yunnan subjects showed high prevalence of sIgE positivity for crabs and shrimps, either by overall or by age-group analysis, compared with their Guangdong counterparts (both P < 0.05). These findings may add to data about local allergies in China and worldwide.
Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b
Authors: Engkvist M. E. , Stratford E. W. , Lorenz S. , Meza-Zepeda L. A. , Myklebost O. , Munthe E. 
Published: August 2017

AbstractThe microRNAs in the miR-34 family, consisting of miR-34a, miR-34b and miR-34c, are tumour suppressors. The annotated human miR-34b-5p has one additional base at the 5’ end of the common miR-34 family seed sequence, compared to miR-34a-5p and miR-34c-5p. This extra base results in a shift of the seed sequence, which would affect the target gene repertoire and have functional consequences. During our studies of miR-34 functions, we investigated the precise sequence of mature miR-34b-5p in human cells by deep sequencing. We found that a miR-34b-5p without the extra base was the predominant form in both non-malignant and malignant cells derived from several human tissues, indicating that the miR-34b annotation is misleading. We evaluated the functional implications of the seed shift, by comparing the effect of mimics representing the alternative miR-34b-5p sequences in MDA-MB-231 cells. In contrast to the annotated miR-34b, the endogenously expressed miR-34b displayed tumour suppressive characteristics in vitro similarly to miR-34c. These data demonstrate the importance of determining the precise sequence of a mature microRNA before exploring miRNA functions.
Elucidation of potential sites for antibody engineering by fluctuation editing
Authors: Yanaka Saeko , Moriwaki Yoshitaka , Tsumoto Kouhei , Sugase Kenji 
Published: August 2017

AbstractTarget-specific monoclonal antibodies can be routinely acquired, but the sequences of naturally acquired antibodies are not always affinity-matured and methods that increase antigen affinity are desirable. Most biophysical studies have focused on the complementary determining region (CDR), which directly contacts the antigen; however, it remains difficult to increase the affinity as much as desired. While strategies to alter the CDR to increase antibody affinity are abundant, those that target non-CDR regions are scarce. Here we describe a new method, designated fluctuation editing, which identifies potential mutation sites and engineers a high-affinity antibody based on conformational fluctuations observed by NMR relaxation dispersion. Our data show that relaxation dispersion detects important fluctuating residues that are not located in the CDR and that increase antigen–antibody affinity by point mutation. The affinity-increased mutants are shown to fluctuate less in their free form and to form a more packed structure in their antigen-bound form.
Point defect formation in M2AlC (M = Zr,Cr) MAX phases and their tendency to disorder and amorphize
Authors: Shah S. H. , Bristowe P. D. 
Published: August 2017

AbstractFirst principles calculations are performed on Zr2AlC and Cr2AlC MAX phases to compare their ability to accommodate point defects under irradiation. Interatomic bonding is stronger in Cr2AlC than Zr2AlC but contrary to expectation Zr2AlC exhibits higher vacancy and antisite pair formation energies. However, interstitials and Frenkel defects are generally more difficult to form in Cr2AlC. The results are attributed to the mixed covalent/ionic/metallic nature of the bonding. Detailed comparison of all the energies suggests that the preferred defects in Zr2AlC and Cr2AlC are the VAl+Ali Frenkel and CrAl+AlCr antisite respectively. Thus the potential response of the two phases to irradiation is different and taking account of other competing defects it is suggested that Zr2AlC is less susceptible to amorphization.
ForCenS, a curated database of planktonic foraminifera census counts in marine surface sediment samples
Authors: Siccha Michael , Kucera Michal 
Published: August 2017

AbstractCensus counts of marine microfossils in surface sediments represent an invaluable resource for paleoceanography and for the investigation of macroecological processes. A prerequisite for such applications is the provision of data syntheses for individual microfossil groups. Specific to such syntheses is the necessity of taxonomical harmonisation across the constituent datasets, coupled with dereplication of previous compilations. Both of these aspects require expert knowledge, but with increasing number of records involved in such syntheses, the application of expert knowledge via manual curation is not feasible. Here we present a synthesis of planktonic foraminifera census counts in surface sediment samples, which is taxonomically harmonised, dereplicated and treated for numerical and other inconsistencies. The data treatment is implemented as an objective and largely automated pipeline, allowing us to reduce the initial 6,984 records to 4,205 counts from unique sites and informative technical or true replicates. We provide the final product and document the procedure, which can be easily adopted for other microfossil data syntheses.