bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of the nacnac Ligand in Iron(I)‐Mediated P4 Transformations
Authors: Spitzer Fabian , Graßl Christian , Balázs Gábor , Zolnhofer Eva M. , Meyer Karsten , Scheer Manfred 
Published: February 2016

AbstractA study of P4 transformations at low‐valent iron is presented using β‐diketiminato (L) FeI complexes [LFe(tol)] (tol=toluene; L=L1 (1 a), L2 (1 b), L3 (1 c)) with different combinations of aromatic and backbone substituents at the ligand. The products [(LFe)4(μ4‐η2:η2:η2:η2‐P8)] (L=L1 (2 a), L2 (2 b)) containing a P8 core were obtained by the reaction of 1 a,b with P4 in toluene at room temperature. Using a slightly more sterically encumbered ligand in 1 c results in the formation of [(L3Fe)2(μ‐η4:η4‐P4)] (2 c), possessing a cyclo‐P4 moiety. Compounds 2 a–c were comprehensively characterized and their electronic structures investigated by SQUID magnetization and 57Fe Mössbauer spectroscopy as well as by DFT methods.
Decomposition of the potassic rocks by sub‐molten salt method and synthesis of low silica X zeolite
Authors: Miao Qingyu , Zhao Bin , Liu Sijia , Guo Juhua , Tong Yuejin , Cao Jilin 
Published: February 2016

AbstractIn this work, the potassic rock (PR), an ore rich in aluminosilicate and alkali metal sources, was decomposed to active amorphous material in mild condition for the first time via sub‐molten salt method. Low silica X (LSX) zeolite was successfully synthesized using the amorphous precursor from PRs as starting material. The effects of temperature, time, and mass concentration of alkali on the decomposition of PRs powder, and the effects of molar ratios of SiO2/Al2O3 and H2O/(Na2O + K2O) on the synthesis of LSX zeolite, were investigated. X‐ray powder diffraction, scanning electron microscopy, energy dispersive X‐ray spectrometer, and Fourier transform infrared spectroscopy were employed to characterize the precursors and as‐prepared zeolites. The results indicated that the highly active amorphous precursor can be obtained in (Na, K)OH sub‐molten salt medium with 80% of mass concentration of alkali at 190 °C for 3.0 h. The LSX zeolite can be synthesized in 5.85Na2O:1.65K2O:Al2O3:(2.1–2.3)SiO2:(113–125)H2O system using the slurry obtained from the decomposition of PRs. Copyright © 2016 Curtin University of Technology and John Wiley & Sons, Ltd.
Effect of light component on the regulation of quinoline insolubility in pitch during thermal treatment
Authors: Liu Peng , Zhang Dexiang , Yang Xu 
Published: February 2016

AbstractPitches with different contents of light component were obtained from the high‐temperature coal tar by distillation. The effect of the light component on the thermal polymerization of pitch was investigated using a laboratory autoclave. The component distribution in the original pitch was determined by gel permeation chromatography. The variation of carbon distribution in the modified pitch was monitored by solid‐state 13C nuclear magnetic resonance. The results show that the variation of quinoline insolubility (QI) in the modified pitch during thermal treatment is markedly influenced by the amount of light component. When the light components exist in the original pitch, the QI in the modified pitch decreases at a low temperature (below 683 K) during the initial reaction stage and subsequently increases. The toluene insolubility of the modified pitch invariably increases. When the light components are added in the original pitch with a higher softening point, the results show the same trend of decrease of QI in the modified pitch. It can be included that the QI content in the modified pitch can be regulated by both the thermal polymerization conditions and the contents of the light component in the original pitch. Copyright © 2016 Curtin University of Technology and John Wiley & Sons, Ltd.
Fabrication of a poly(ɛ‐caprolactone)/starch nanocomposite scaffold with a solvent‐casting/salt‐leaching technique for bone tissue engineering applications
Authors: Taherkhani Safa , Moztarzadeh Fathollah 
Published: February 2016

ABSTRACTA series of nanocomposite scaffolds of poly(ɛ‐caprolactone) (PCL) and starch with a range of porosity from 50 to 90% were fabricated with a solvent‐casting/salt‐leaching technique, and their physical and mechanical properties were investigated. X‐ray diffraction patterns and Fourier transform infrared spectra confirmed the presence of the characteristic peaks of PCL in the fabricated scaffolds. Microstructure studies of the scaffolds revealed a uniform pore morphology and structure in all of the samples. The experimental measurements showed that the average contact angle of the PCL/starch composite was 88.05 ± 1.77°. All of the samples exhibited compressive stress/strain curves similar to those of polymeric foams. The samples with 50, 60, 70, and 80 wt % salt showed compressive‐load‐resisting capabilities in the range of human cancellous bone. With increasing porosity, a significant decrease in the mechanical properties of the scaffolds was observed. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2016,133, 43523.
Inkjet printing of polylactic acid on substrates prepared by fused deposition modeling and its potential for selective surface finishing
Authors: Köpplmayr Thomas , Mühlberger Michael 
Published: February 2016

ABSTRACTFused deposition modeling (FDM) is an additive manufacturing technology commonly used for prototyping. One limiting aspect for the use in functional prototyping and small‐lot production is the achievable surface roughness. The aim of this work was to investigate a potential method of processing polylactic acid (PLA), as it is commonly used for FDM printing, via inkjet technology. PLA solvent inks with different concentrations were prepared by dissolving PLA in 1,4‐dioxane. The tested PLA substrates were prepared by FDM with different layer thicknesses and the change in surface roughness after multilayer inkjet printing was measured by a stylus profilometer. The surface roughness was reduced by up to 50% and further increasing the number of inkjet layers caused voids and PLA accumulations. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43527.
First‐principles Study on the Charge Transport Mechanism of Lithium Sulfide (Li2S) in Lithium‐Sulfur Batteries
Authors: Kim B. S. Do‐Hoon , Lee M. S. Byungju , Park Kyu‐Young , Kang Kisuk 
Published: February 2016

AbstractThe lithium‐sulfur chemistry is regarded as a promising candidate for next‐generation battery systems because of its high specific energy (1675 mA h g−1). Although issues such as low cycle stability and power capability of the system remain to be addressed, extensive research has been performed experimentally to resolve these problems. Attaining a fundamental understanding of the reaction mechanism and its reaction product would further spur the development of lithium‐sulfur batteries. Here, we investigated the charge transport mechanism of lithium sulfide (Li2S), a discharge product of conventional lithium‐sulfur batteries using first‐principles calculations. Our calculations indicate that the major charge transport is governed by the lithium‐ion vacancies among various possible charge carriers. Furthermore, the large bandgap and low concentration of electron polarons indicate that the electronic conduction negligibly contributes to the charge transport mechanism in Li2S.
Photoinduced electron transfer reactions of pyranine with benzoquinone and titanium dioxide
Authors: Kathiravan A. , Asha Jhonsi M. 
Published: February 2016

AbstractThe fluorescence quenching of pyranine by benzoquinone in acetonitrile medium was studied using steady‐state and time‐resolved fluorescence techniques. The quenching process was characterized by a Stern–Volmer plot, which displayed a linear aspect. From the linear plot, the bimolecular quenching rate constant was obtained. The obtained rate constants are within diffused controlled limits. The results show that benzoquinone can efficiently quench the fluorescence of pyranine with dynamic quenching rate constants in the order of 1010 M–1 s–1, suggesting that the pyranine can act as a good electron donor for photoinduced electron transfer in artificial photosynthesis and organic solar cells. In addition, the electron injection dynamics of a pyranine/titanium dioxide semiconductor film was also investigated and electron injection from the excited state pyranine into the conduction band of titanium dioxide is suggested. These preliminary results hold promise for the possibility of using pyranine in dye‐sensitized solar cells. Copyright © 2016 John Wiley & Sons, Ltd.
Systematical investigation of binding interaction between novel ruthenium(II) arene complex with curcumin analogs and ctDNA
Authors: Huang Shan , Liang Yu , Huang Chusheng , Su Wei , Lei Xiaolin , Liu Yi , Xiao Qi 
Published: February 2016

AbstractIn this study, the interaction between a novel ruthenium(II) arene complex with curcumin analogs and calf thymus DNA (ctDNA) was investigated systematically by viscosity measurement, the DNA melting approach, multispectroscopic techniques and electrochemical methods. The absorption spectra of the ctDNA–drug complex showed a slight red shift and a weak hypochromic effect. The relative viscosity and melting temperature of ctDNA increased on addition of the drug. The evidence obtained from fluorescence competitive experiments indicated that the binding mode of the drug with ctDNA was intercalative. Using acridine orange (AO) as a fluorescence probe, the drug statically quenched the fluorescence of the ctDNA–AO complex, and hydrogen bonding and van der Waals interactions played vital roles in the binding interaction between the drug and ctDNA. The influences of ionic strength, chemical denaturants and pH on the binding interaction were also investigated. Circular dichroism and Fourier transform infrared spectra suggested that this drug might bond with the G–C base pairs of ctDNA and the right‐handed B‐form helicity of ctDNA remained after drug binding. The intercalative binding between the drug and ctDNA was further investigated using electrochemical techniques. All these results suggested that the biological activity of ctDNA was affected by ruthenium(II) arene complex with curcumin analogs. Copyright © 2016 John Wiley & Sons, Ltd.
Patient-reported outcomes and their predictors at 2- and 3-year follow-up after immediate latissimus dorsi breast reconstruction and adjuvant treatment
Authors: Winters Z E , Afzal M , Balta V , Freeman J , Llewellyn-Bennett R , Rayter Z , Cook J , Greenwood R , King M T , Hallam S , Weiler-Mithoff E , Nicholson S , McManus P , Galea M , Benson J 
Published: February 2016

Abstract

Background
The aim of this study was to estimate the impact 2 and 3 years after surgery of implant-assisted latissimus dorsi (LDI) and autologous latissimus dorsi (ALD) flap breast reconstructions on patient-reported outcomes (PROs), and, secondarily, to determine whether baseline characteristics can predict PROs.

Methods
This was a multicentre prospective cohort study. The European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) and breast cancer module (QLQ-BR23), Functional Assessment of Cancer Therapy – Breast (FACT-B), and Hospital Anxiety and Depression Scale (HADS) PROs were completed before surgery and at 2 and 3 years after breast reconstruction. The effects of LDI and ALD, adjusted for baseline clinicodemographic characteristics, were estimated with multiple linear regressions. Effect sizes above 0·5 were considered clinically important.

Results
Some 206 patients (LDI 93, ALD 113) were recruited in 2007–2013; 66·5 per cent were node-negative and 34·6 per cent received radiotherapy. Women with adverse clinicopathological factors were more likely to have received radiotherapy and to undergo ALD. Patients in both surgical groups showed clinically important effects at 2 and 3 years, including improvements in emotional scales, but worse physical functioning, social well-being, body image and anxiety. Radiotherapy adversely affected social functioning at 2 years (P = 0·002). Women undergoing ALD reconstruction had significantly improved sexual functioning at 3 years (P = 0·003) relative to those who had LDI procedures, even after adjusting for case mix (P = 0·007). At 3 years, younger women experienced worse physical well-being than older women (P = 0·006), and chemotherapy was associated with worse arm symptoms (P = 0·005).

Conclusion
Clinically important changes occurred in physical functioning, breast symptoms, body image and psychological distress. These results will guide selections of key PRO domains and sample-size calculation of future studies.
Meta-analysis of antibiotics for simple hand injuries requiring surgery
Authors: Murphy G R F , Gardiner M D , Glass G E , Kreis I A , Jain A , Hettiaratchy S 
Published: February 2016

AbstractBackgroundSimple hand trauma is very common, accounting for 1·8 million emergency department visits annually in the USA alone. Antibiotics are used widely as postinjury prophylaxis, but their efficacy is unclear. This meta-analysis assessed the effect of antibiotic prophylaxis versus placebo or no treatment on wound infection rates in hand injuries managed surgically.MethodsEmbase, MEDLINE, PubMed, Cochrane Central, ClinicalTrials.gov and the World Health Organization International Clinical Trials Portal were searched for published and unpublished studies in any language from inception to September 2015. The primary outcome was the effect of antibiotic prophylaxis on wound infection rates. Open fractures, crush injuries and bite wounds were excluded. Study quality was assessed using the Cochrane risk-of-bias tool. Data were pooled using random-effects meta-analysis, and risk ratios (RRs) and 95 per cent c.i. obtained.ResultsThirteen studies (2578 patients) were included, comprising five double-blind randomized clinical trials, five prospective trials and three cohort studies. There was no significant difference in infection rate between the antibiotic and placebo/no antibiotic groups (RR 0·89, 95 per cent c.i. 0·65 to 1·23; P = 0·49). Subgroup analysis of the five double-blind randomized clinical trials (864 patients) again found no difference in infection rates (RR 0·66, 0·36 to 1·21; P = 0·18).ConclusionThere was moderate-quality evidence that routine use of antibiotics does not reduce the infection rate in simple hand wounds that require surgery.
Ethernet and PC‐based experiments on barometric altimetry using MEMS in a wireless sensor network
Authors: Bolanakis Dimosthenis E. , Kotsis Konstantinos T. , Laopoulos Theodore 
Published: February 2016

ABSTRACTThis paper presents a training framework that applies to Micro‐Electro‐Mechanical‐Systems (MEMS) technology. Recommendations are in line with a prototype educational platform along with an innovative set of experiments for a creative training on barometric altimetry. The proposed platform relies on a wireless sensor network system of Ethernet as well as PC‐based (i.e., LabVIEW) user interface for ambient air pressure acquisition. The web user interface renders feasible the implementation of a single setup per class, while also minimizes students' occupation on software and hardware configuration activities; hence, students are concentrated on the problem solving process. The LabVIEW controlled interface advocates tutor‐demonstration by means of real‐time graphical monitoring of the measurement procedure. The wireless system feature provides flexibility in experimentation, allowing the examination of particular sensor characteristics (related to the design of a MEMS system) that regularly require an exceptionally expensive apparatus. © 2016 Wiley Periodicals, Inc. Comput Appl Eng Educ 24:443–455, 2016; View this article online at wileyonlinelibrary.com/journal/cae; DOI 10.1002/cae.21722
MiR‐24 enhances radiosensitivity in nasopharyngeal carcinoma by targeting SP1
Authors: Kang Min , Xiao Jingjian , Wang Jun , Zhou Pingting , Wei Tingting , Zhao Tingting , Wang Rensheng 
Published: February 2016

AbstractRadioresistance remains a major problem in the treatment of patients suffering from nasopharyngeal carcinoma (NPC). A better understanding of the mechanisms of radioresistance may generate new strategies to improve NPC patients' responses to therapy. This study was designed to investigate the effect of microRNA on the radiosensitivity of NPC cells. A microRNA microarray indicated that miR‐24 was downregulated in NPC cell lines and tissues. Furthermore, cell proliferation was suppressed and radiosensitivity increased when miR‐24 was ectopically expressed in NPC cells. Specificity protein 1 (SP1) was additionally verified as a direct functional target of miR‐24, which was found to be involved in cell viability as well as the radiosensitivity of NPC cells. In conclusion, the results of this study suggest that the miR‐24/SP1 pathway contributed to the reduction in radioresistance in human NPC and that it may thus represent a therapeutic target.
Recreational physical activity and ovarian cancer risk in African American women
Authors: Abbott Sarah E. , Bandera Elisa V. , Qin Bo , Peres Lauren C. , Moorman Patricia G. , Barnholtz‐Sloan Jill , Schwartz Ann G. , Funkhouser Ellen , Peters Edward S. , Cote Michele L. , Alberg Anthony J. , Terry Paul , Bondy Melissa , Paddock Lisa E. , Crankshaw Sydnee , Wang Frances , Camacho Fabian , Schildkraut Joellen M. 
Published: February 2016

AbstractThe literature on recreational physical activity (RPA) and ovarian cancer risk is inconclusive and most studies of RPA and ovarian cancer have been conducted in white populations. This study is the first to investigate the association between RPA and ovarian cancer in an exclusively African American (AA) population. We analyzed data from an ongoing U.S. population‐based, case–control study of AA women, which included 393 women recently diagnosed with invasive epithelial ovarian cancer (IEOC) and 611 controls. A baseline interview assessed RPA frequency, intensity, and duration. Each RPA intensity was assigned a metabolic equivalent of task (MET) value and MET‐min/week were calculated. Unconditional multivariable logistic regression was performed to investigate associations between RPA and IEOC risk. Compared with sedentary women, predominantly mild intensity RPA was significantly inversely associated with IEOC risk for women reporting above median (>297) MET‐min/week (odds ratio [OR] = 0.52; 95% confidence interval [CI]: 0.34, 0.78) and nonsignificantly for <297 MET‐min/week (OR = 0.71; 95% CI: 0.44, 1.12). Predominantly moderate intensity RPA was associated with significantly increased risk for women reporting above median (>540) MET‐min/week (OR = 1.51; 95% CI: 1.03, 2.23). Predominantly strenuous intensity RPA was nonsignificantly associated with lower IEOC risk for women reporting above median (>1800) MET‐min/week (OR = 0.72; 95% CI: 0.33, 1.57). The inverse associations for mild and strenuous intensity RPA were most pronounced in obese women (body mass index >30 kg/m2). The findings that mild and strenuous RPA may reduce the risk of IEOC particularly among obese women are difficult to reconcile with the increased risk observed for moderate RPA. Further research is warranted to determine whether these findings are genuine and, if so, their mechanistic basis.
Body mass index and survival after diagnosis of invasive breast cancer: a study based on the Japanese National Clinical Database—Breast Cancer Registry
Authors: Kawai Masaaki , Tomotaki Ai , Miyata Hiroaki , Iwamoto Takayuki , Niikura Naoki , Anan Keisei , Hayashi Naoki , Aogi Kenjiro , Ishida Takanori , Masuoka Hideji , Iijima Kotaro , Masuda Shinobu , Tsugawa Koichiro , Kinoshita Takayuki , Nakamura Seigo , Tokuda Yutaka 
Published: February 2016

AbstractFew studies have reported the association between body mass index (BMI) and outcome among Asian breast cancer patients. We analyzed data for 20,090 female invasive breast cancer patients who had been followed‐up for a median period of 6.7 years entered in the National Clinical Database–Breast Cancer Registry between 2004 and 2006. We used mainly theWHOcriteria forBMI (kg/m2) categories; <18.5 (underweight), ≥18.5–<21.8 (reference), ≥21.8–<25, ≥25–<30 (overweight), and ≥30 (obese). We divided normal weight patients into two subgroups because this category includes many patients compared to others. The timing ofBMImeasurement was not specified. The Cox proportional hazards model and cubic spline regression were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Smoking, alcohol, and physical activity were not controlled. A total of 1418 all‐cause, 937 breast cancer–specific deaths, and 2433 recurrences were observed. Obesity was associated with an increased risk of all‐cause (HR: 1.46; 95%CI: 1.16–1.83) and breast cancer–specific death (HR: 1.47; 95%CI: 1.11–1.93) for all patients, and with all‐cause (HR: 1.47; 95%CI: 1.13–1.92) and breast cancer–specific death (HR: 1.58; 95%CI: 1.13–2.20) for postmenopausal patients. Being underweight was associated with an increased risk of all‐cause death for all (HR: 1.41; 95%CI: 1.16–1.71) and for postmenopausal patients (HR: 1.45; 95%CI: 1.15–1.84). With regard to subtype and menopausal status, obesity was associated with an increased risk of breast cancer–specific death for all cases of luminal B tumor (HR: 2.59; 95%CI: 1.51–4.43; Pheterogeneityof Luminal B vs. Triple negative = 0.016) and for postmenopausal patients with luminal B tumor (HR: 3.24; 95%CI: 1.71–6.17). Being obese or underweight is associated with a higher risk of death among female breast cancer patients in Japan.
Unilateral lower abdominal wall protrusion and umbilical deviation
Authors: Shikino Kiyoshi , Miyahara Masahito , Noda Kazutaka , Ohira Yoshiyuki , Ikusaka Masatomi 
Published: February 2016

Key Clinical MessagePostherpetic pseudohernia must be suspected when a patient develops motor dysfunction coincident with or following a herpes zoster eruption.
Should the BK polyomavirus cytopathic effect be best classified as atypical or benign in urine cytology specimens?
Authors: Allison Derek B. , Olson Matthew T. , Lilo Mohammed , Zhang Mingjuan L. , Rosenthal Dorothy L. , VandenBussche Christopher J. 
Published: February 2016

BACKGROUNDAccording to The Paris System for Reporting Urinary Cytology (TPS), the category of atypical urothelial cells (AUC) should not be applied to specimens in which cellular changes can be entirely attributed to the polyoma (BK) virus cytopathic effect (CPE). Until recently, cases with BK CPE at The Johns Hopkins Hospital were categorized as atypical urothelial cells of uncertain significance (AUC‐US), which is equivalent to the TPS AUC category. This study was performed to determine how significantly the rate of AUC‐US specimens would decrease if specimens with only BK CPE were classified as benign.METHODSTwo reviewers and 1 adjudicator re‐evaluated urinary tract specimens to determine whether sufficient cytological atypia justified an AUC‐US diagnosis independent of the presence of BK CPE. For patients with surgical follow‐up, the rate of high‐grade urothelial carcinoma (HGUC) on tissue biopsy was tracked over a 5‐year period.RESULTSThe reclassification rate of AUC‐US cases with BK CPE as benign was 62.6%. The rate of subsequent HGUC was 6.0% for cases reclassified as benign and 10.0% for cases still classified as AUC‐US. These rates were not significantly elevated in comparison with control cohorts among all‐comers. However, for patients without a history of HGUC, the rate of HGUC on follow‐up was significantly elevated in comparison with the rate for a benign control cohort and was similar to the rate for the AUC‐US control cohort.CONCLUSIONSReclassification as benign would have decreased the rate of AUC‐US from 24.8% to 20.7% during the study year. However, the high rate of subsequent HGUC among nonsurveillance patients suggests that the reclassification of specimens with BK CPE in these patients may be inappropriate. Cancer Cytopathol 2016;124:436–42. © 2016 American Cancer Society.