bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research
Authors: Burgoyne Laura L. , Simmons Scott W. , Cyna Allan M. 
Published: September 2024

Abstract
Any anaesthetist can, through an iterative process and the assistance of an experienced instructor, learn to take a clinical question through to publication. One of the greatest communication challenges for researchers is responding to a journal after a paper has been reviewed. Draft manuscripts are rarely accepted on first submission, and persistence is required to see research through to publication. Addressing reviewer comments not only allows the manuscript to be published but almost always improves it. It is important to accept the reviewers’ point of view, because even if you disagree with them, their comments can nearly always be utilized as a basis for a constructive response. However, it is okay to disagree politely, objectively, and concisely, clarifying any issues in the response and draft manuscript. A would-be researcher responding to feedback from a journal will be better placed by having gone through the process themselves as a reviewer.
Administrators
Authors: Simmons Scott W. 
Published: September 2024

Abstract
Applying the concepts of ‘GREAT’ and ‘LAURS’ the clinician manager can optimize working with administrators to achieve mutually beneficial outcomes, underpinned by a philosophy of seeking common ground and positive-sum gains. Directors of Anaesthesia can be thrust into the affray in the seemingly obscure and somewhat confronting world of the CEO. Communication techniques can be applied in conflict diagnosis and resolution. Readily transferable negotiation skills provide possible approaches to what are everyday problems of managing staffing shortages and interpersonal conflict. The importance of attention to detail not only in regard to content, but also the setting and mode of communication requires being succinct and taking into account fiscal considerations, as well as acknowledging and effectively managing the personal emotional impact that commonly accompanies high-level, high-stakes interactions.
Associations Between Sleep Disorders and Treatment Response in Service Members With Post-traumatic Stress Symptoms: A Secondary Outcome Analysis
Authors: Abanes Jane J , Raiciulescu Sorana 
Published: September 2024

ABSTRACT

Introduction
Compared with the civilian population, a higher rate of reported sleep apnea exists among military service members resulting in inadequate sleep. Those who experience chronic sleep deprivation may suffer from debilitating problems that may compromise military mission readiness and unit safety. The purpose of the study on which this secondary outcome analysis was based was to evaluate the effect of manual standardized stress acupuncture as an adjunct therapy to an abbreviated form of cognitive behavioral therapy for insomnia for sleep disturbances in post-deployment service members. The aim of this secondary outcome analysis was 2-fold: (1) to assess the relationship between sleep disorder symptoms and post-traumatic stress symptoms (PSS) and (2) to determine if the presence of sleep disorder symptoms influenced the effects of acupuncture and cognitive behavioral therapy as compared to cognitive behavior therapy only on PSS) in post-deployment military service members.

Materials and Methods
The study was a 2-arm, single-center, randomized controlled trial approved by the Naval Medical Center San Diego and the Vanderbilt University Institutional Review Board. It was conducted at the U.S. Naval Hospital in Okinawa, Japan. Participants were active duty service members from all military branches who were stationed in Okinawa. Two measures were used to analyze the data: the Global Sleep Assessment Questionnaire (GSAQ) and the Post-traumatic Stress Disorder Checklist. A Pearson correlation coefficient was calculated to determine the relationship between sleep disorder symptoms (i.e., 11 pre-intervention GSAQ symptoms) and PSS treatment outcomes (i.e., PCL and PTSD clusters).

Results
Results indicated associations between the GSAQ components and PCL total and PTSD cluster scores. Findings showed that the presence of sleep disorder symptoms influenced PSS treatment response in post-deployment military service members.

Conclusions
Results from this secondary outcome analysis showed associations between GSAQ components (i.e., excessive daytime sleepiness, working conditions causing inadequate sleep, involuntary movements in sleep, and sadness or anxiousness) and PCL total and PTSD cluster scores (i.e., avoidance, negative cognition and mood, avoidance, and hyperarousal). Furthermore, sleep disorder symptoms such as having stressful working conditions (e.g., shift work), probable obstructive sleep apnea, insomnia, anxiety, and depression influenced PSS treatment responses. This study provided information on the major contribution of sleep disorder symptoms in the treatment of PSS through self-report. Future researchers should consider the use of physiologic measures to further understand the mechanisms of how sleep disorder symptoms affect treatment responses in service members with PSS. Implications for this study may assist clinicians in determining effective PSS treatments for those with OSA and insomnia.
The generation of a multiphase medium in ‘Splash’ bridge systems: towards an understanding of star formation suppression in turbulent galaxy systems
Authors: Yeager Travis R , Struck Curtis , Appleton Phil 
Published: September 2024

ABSTRACT
Cloud–cloud collisions in splash bridges produced in gas-rich disc galaxy collisions offer a brief but interesting environment to study the effects of shocks and turbulence on star formation rates in the diffuse intergalactic medium, far from the significant feedback effects of massive star formation and active galactic nucleus. Expanding on our earlier work, we describe simulated collisions between counter-rotating disc galaxies of relatively similar mass, focusing on the thermal and kinematic effects of relative inclination and disc offset at the closest approach. This includes essential heating and cooling signatures, which go some way towards explaining the luminous power in H$_2$ and [C ii] emission in the Taffy bridge, as well as providing a partial explanation of the turbulent nature of the recently observed compact CO-emitting clouds observed in Taffy by the Atacama Large Millimeter Array (ALMA). The models show counter-rotating disc collisions result in swirling, shearing kinematics for the gas in much of the post-collision bridge. Gas with little specific angular momentum due to collisions between counter-rotating streams accumulates near the centre of mass. The disturbances and mixing in the bridge drive continuing cloud collisions, differential shock heating, and cooling throughout. A wide range of relative gas phases and line-of-sight velocity distributions are found in the bridges, depending sensitively on initial disc orientations, and the resulting variety of cloud collision histories. Most cloud collisions can occur promptly or persist for quite a long duration. Cold and hot phases can largely overlap throughout the bridge or can be separated into different parts of the bridge.
Energy equipartition in multiple-population globular clusters
Authors: Livernois Alexander R , Aros F I , Vesperini E , Askar A , Bellini A , Giersz M , Hong J , Hypki A , Libralato M , Ziliotto T 
Published: September 2024

ABSTRACT
We present the results of Monte Carlo simulations aimed at exploring the evolution towards energy equipartition of first- (1G) and second-generation (2G) stars in multiple-population globular clusters and how this evolution is affected by the initial differences between the spatial distributions of the two populations. Our results show that these initial differences have fundamental implications for the evolution towards energy equipartition of the two populations. We find that 2G stars, which are assumed to be initially more centrally concentrated than 1G stars, are generally characterized by a more rapid evolution towards energy equipartition. The evolution towards energy equipartition depends on the velocity dispersion component and is more rapid for the tangential velocity dispersion. The extent of the present-day differences between the degree of energy equipartition of 2G and 1G stars depends on the cluster’s dynamical age and may be more significant in the tangential velocity dispersion and at intermediate distances from the cluster’s centre around the half-mass radius.
Gaia BH1 and BH2 – evolutionary models with overshooting of the black hole progenitors within the present-day binary separation
Authors: Gilkis A , Mazeh T 
Published: September 2024

ABSTRACT
Three black holes (BHs) in wide binaries – Gaia BH1, BH2, and BH3 – were recently discovered. The likely progenitors of the BHs were massive stars that experienced a supergiant phase, reaching radii of $\sim\!\! 1000 \ \mathrm{ R}_{\odot }$, before collapsing to form the BH. Such radii are difficult to accommodate with the present-day orbits of BH1 and BH2 – with semimajor axes of 1.4 and 3.7 au, respectively. In this letter, we show that the maximal radii of the supergiants are not necessarily so large, and realistic stellar evolution models, with some assumed overshooting above the convective core into the radiative stellar envelope, produce substantially smaller maximal radii. The limited expansion of supergiants is consistent with the empirical Humphreys–Davidson limit – the absence of red supergiants above an upper luminosity limit, notably lower than the highest luminosity of main-sequence stars. We propose that the evolution that led to the formation of Gaia BH1 and BH2 simply did not involve an expansion to the cool supergiant phase.
Non–Sugar-Sweetened Beverages and Risk of Chronic Diseases: An Umbrella Review of Meta-analyses of Prospective Cohort Studies
Authors: Beigrezaei Sara , Raeisi-Dehkordi Hamidreza , Hernández Vargas Juliana Alexandra , Amiri Mojgan , Artola Arita Vicente , van der Schouw Yvonne T , Salehi-Abargouei Amin , Muka Taulant , Chatelan Angeline , Franco Oscar H 
Published: September 2024

Abstract

Context
Several effects of non–sugar-sweetened beverage (NSSBs) intake on health outcomes have been reported; however, the evidence on the association between NSSBs intake and chronic diseases and mortality risk is still inconclusive.

Objective
This umbrella review aimed to summarize the evidence on the association between NSSBs intake and the risk of chronic diseases and mortality.

Data Sources
Embase, ISI Web of Science, Cochrane Central, and PubMed were searched up to September 2023 for relevant meta-analyses of observational prospective cohort studies.

Data Extraction
Two groups of researchers independently extracted study data and assessed the risk of bias for meta-analyses and primary studies.

Data Analysis
Six meta-analyses, reporting 74 summary hazard ratios (HRs) for different outcomes obtained from 50 primary studies, were included. The summary HRs, 95% CIs, and certainty of evidence on the association of NSSBs intake with risk of chronic diseases and mortality were as follows: all-cause mortality (per 355 mL/d: 1.06 [1.01 to 1.10]; moderate certainty); stroke (per 250 mL/d: 1.09 [1.04 to 1.13]; high certainty); coronary heart disease (CHD) (per 250 mL/d: 1.06 [1.02 to 1.11]; high certainty); hypertension (HTN) (high vs low intake: 1.14 [1.09 to 1.18]; moderate certainty); type 2 diabetes (T2D) (high vs low intake: 1.16 [1.08 to 1.26]; low certainty); metabolic syndrome (MetS) (high vs low intake: 1.32 [1.22 to 1.43]; low certainty); colorectal cancer (high vs low intake: 0.78 [0.62 to 0.99]; moderate certainty); and leukemia (high vs low intake: 1.35 [1.03 to 1.77]; moderate certainty). For other outcomes, including the risk of cardiovascular and cancer mortality, chronic kidney diseases, breast cancer, prostate cancer, endometrial cancer, pancreatic cancer, multiple myeloma, and non-Hodgkin lymphoma, no association was found.

Conclusion
This study provides further evidence that NSSBs are associated with increased risk of all-cause mortality, stroke, CHD, HTN, T2D, MetS, and leukemia. Moreover, a higher intake of NSSBs was associated with a lower risk of colorectal cancer. However, it should be noted that the magnitudes of the associations are not large. Further studies are needed to clarify the long-term effects of different NSSBs intakes on health.

Systematic Review Registration
PROSPERO no. CRD42023429981.
Morphometric variation and deteriorating food availability both explain seasonally declining reproductive success of Dicrurus hottentottus (Hair-crested Drongo)
Authors: Liu Chen-Yang , Lv Lei , Li Jianqiang , Liu Yang , Zhang Zhengwang , Komdeur Jan 
Published: September 2024

ABSTRACT
Seasonally declining reproductive performance in avian populations may be attributed to high-quality individuals breeding earlier than low-quality individuals (the quality hypothesis), to deteriorating environmental conditions (the date hypothesis), or both. By comparing the reproductive performance among different perennial pairs, and the same perennial pairs across different years, we tested the influence of timing of breeding on reproductive performance in Dicrurus hottentottus (Hair-crested Drongo) from 2010 to 2022. Breeding pairs that typically laid earlier relative to the population mean (i.e., early-breeding pairs) exhibited a significantly higher fledging rate compared to breeding pairs that often bred later relative to the population mean (i.e., late-breeding pairs). For a given pair, the fledging rate of early-breeding pairs increased when they bred later compared to other years, while the fledging rates of late-breeding pairs were significantly lower in years when they bred later than usual. We found that male morphological traits were associated with both the timing of breeding and the feeding rate. Pairs with long-billed (indicator of high quality) males bred earlier than pairs with short-billed males, and pairs with larger males (indicator of high quality) had a higher feeding rate than pairs with smaller males. Female age had reversed effects on the timing of breeding and fledging rate: older females tended to breed earlier than younger females; but there was a sharp decline in fledging rate after 7 years of age in late-breeding pairs. Finally, our results showed that the feeding rate and the amount of invertebrate biomass decreased with laying date, indicating deteriorating feeding conditions later in the breeding season. Overall, our findings support both the quality hypothesis and the date hypothesis. Low-quality D. hottentottus are likely to be most adversely affected by the phenological mismatches induced by climate change, which, in turn, may affect population dynamics through reduced fecundity.
A complex and dynamic redox network regulates oxygen reduction at photosystem I in Arabidopsis
Authors: Hani Umama , Naranjo Belen , Shimakawa Ginga , Espinasse Christophe , Vanacker Hélène , Sétif Pierre , Rintamäki Eevi , Issakidis-Bourguet Emmanuelle , Krieger-Liszkay Anja 
Published: September 2024

Abstract
Thiol-dependent redox regulation of enzyme activities plays a central role in regulating photosynthesis. Besides the regulation of metabolic pathways, alternative electron transport is subjected to thiol-dependent regulation. We investigated the regulation of O2 reduction at photosystem I. The level of O2 reduction in leaves and isolated thylakoid membranes depends on the photoperiod in which plants are grown. We used a set of Arabidopsis (Arabidopsis thaliana) mutant plants affected in the stromal, membrane, and lumenal thiol network to study the redox protein partners involved in regulating O2 reduction. Light-dependent O2 reduction was determined in leaves and thylakoids of plants grown in short-day and long-day conditions using a spin-trapping electron paramagnetic resonance assay. In wild-type samples from short-day conditions, reactive oxygen species generation was double that of samples from long-day conditions, while this difference was abolished in several redoxin mutants. An in vitro reconstitution assay showed that thioredoxin m, NADPH-thioredoxin reductase C, and NADPH are required for high O2-reduction levels in thylakoids from plants grown in long-day conditions. Using isolated photosystem I, we also showed that reduction of a photosystem I protein is responsible for the increase in O2 reduction. Furthermore, differences in the membrane localization of m-type thioredoxins and 2-Cys peroxiredoxin were detected between thylakoids of short-day and long-day plants. Overall, we propose a model of redox regulation of O2 reduction according to the reduction power of the stroma and the ability of different thiol-containing proteins to form a network of redox interactions.
Whose knowledge counts? Power dynamics in the co-production of knowledge and innovation in agri-food systems
Authors: Cronin Evelien , Block Thomas , Fosselle Sylvie , Rogge Elke 
Published: September 2024

Abstract
The concept ‘co-production of knowledge and innovation’ (CKI) is gaining prominence. European Union (EU) research and innovation funding programmes like Horizon 2020 (H2020), Horizon Europe, and INTERREG underscore its significance as engaging diverse societal actors is often a requirement. Reality reveals disparities in actor participation in these multinational EU-funded CKI projects. As these projects are perceived as avenues for tackling ‘grand societal challenges’, such as the transition to sustainable agri-food systems, questions arise about whether they ensure equitable inclusion of diverse perspectives, enable genuine participation, and why barriers to entry persist. This study delves into the complexity of multinational CKI projects, shedding light on these questions. One H2020 and one INTERREG project are analysed using the multilevel innovation system framework incorporating a ‘power dynamics’ dimension. By including ‘power dynamics’ in an innovation system-based analysis, we offer a nuanced examination of mechanisms of inclusion and exclusion and a better understanding of potential policy intervention strategies.
MCPIP1 promotes atrial remodeling by exacerbating miR‐26a‐5p/FRAT/Wnt axis–mediated atrial fibrosis in a rat model susceptible to atrial fibrillation
Authors: Li Kai , Sun Huaxin , Bo Yakun , Zhang Wanfeng , Huang Wenchao , Zhao Yang , Yang Hang , Guo Yankai , Zhou Xianhui , Lu Yanmei , Zhang Ling , Tang Baopeng 
Published: September 2024

AbstractAtrial fibrosis plays a critical role in the pathogenesis of atrial fibrillation (AF). Monocyte chemotactic protein–induced protein‐1 (MCPIP1), recognized as a functional ribonuclease (RNase), exacerbates cardiac remodeling and contributes to a range of cardiovascular diseases. However, the involvement of MCPIP1 in atrial fibrosis and development of AF, along with its underlying biological mechanisms, remains poorly understood. This study demonstrated that knockdown of MCPIP1 significantly reduced AF inducibility, decreased left atrial diameter, and ameliorated atrial fibrosis, coinciding with reduced FRAT1/2/Wnt/β‐catenin signaling. Furthermore, the MCPIP1‐D141N mutation attenuated AF vulnerability and atrial remodeling compared to MCPIP1 overexpression in an acetylcholine and calcium chloride (ACh‐CaCl2)–induced rat model of AF. Conversely, overexpression of FRAT1/2 partially reversed the cardioprotective effects of MCPIP1‐D141N mutation. Using H9C2 cell lines, we observed that MCPIP1 may induce a transcriptional effect that downregulates miR‐26a‐5p expression, and luciferase and RNA immunoprecipitation (RIP) assays substantiated the direct interaction between miR‐26a‐5p and FRAT1/2. Moreover, overexpression of miR‐26a‐5p countered MCPIP1‐induced atrial remodeling and attenuated the progression of AF. In conclusion, these findings indicate that MCPIP1 facilitates atrial remodeling and the progression of AF by exacerbating miR‐26a‐5p/FRAT/Wnt axis–mediated atrial fibrosis through its RNase activity in an ACh‐CaCl2–induced rat model of AF.
Second-Line Uterotonics for Uterine Atony
Authors: Cole Naida M. , Kim Jimin J. , Lumbreras-Marquez Mario I. , Fields Kara G. , Mendez-Pino Laura , Farber Michaela K. , Carusi Daniela A. , Toledo Paloma , Bateman Brian T. 
Published: September 2024

OBJECTIVE:
To evaluate the comparative efficacy of two of the most commonly used second-line uterotonics—methylergonovine maleate and carboprost tromethamine.

METHODS:
We conducted a double-blind randomized trial at two large academic perinatal centers in patients undergoing nonemergency cesarean delivery with uterine atony refractory to oxytocin, as diagnosed by the operating obstetrician. The intervention included administration of a single dose of intramuscular methylergonovine or carboprost intraoperatively at diagnosis. The primary outcome, uterine tone on a 0–10 numeric rating scale 10 minutes after study drug administration, was rated by operating obstetricians blinded to the drug administered. Secondary outcomes included uterine tone score at 5 minutes, administration of additional uterotonic agents, other interventions for uterine atony or hemorrhage, quantitative blood loss, urine output, postpartum change in serum hematocrit, transfusion, length of hospital stay, adverse drug or transfusion reactions, and postpartum hemorrhage complications. A sample size of 50 participants per group was planned to detect a 1-point difference (with estimated within-group SD of 1.5) in the mean primary outcome with 80% power at a two-sided α level of 0.05 while accounting for potential protocol violations.

RESULTS:
A total of 1,040 participants were enrolled, with 100 randomized to receive one of the study interventions. Mean±SD 10-minute uterine tone scores were 7.3±1.7 after methylergonovine and 7.6±2.1 after carboprost, with an adjusted difference in means of −0.1 (95% CI, −0.8 to 0.6, P=.76). Additional second-line uterotonics were required in 30.0% of the methylergonovine arm and 34.0% in the carboprost arm (adjusted odds ratio 0.72, 95% CI, 0.27–1.89, P=.505), and geometric mean quantitative blood loss was 756 mL (95% CI, 636–898) and 708 mL (95% CI, 619–810) (adjusted ratio of geometric means 1.06, 95% CI, 0.86–1.31, P=.588), respectively. No differences were detected in the occurrence of other interventions for uterine atony or postpartum hemorrhage.

CONCLUSION:
No difference was detected in uterine tone scores 10 minutes after administration of either methylergonovine or carboprost for refractory uterine atony, indicating that either agent is acceptable.

CLINICAL TRIAL REGISTRATION:

ClinicalTrials.gov, NCT03584854.