bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bone lymphoma with multiple negative bone biopsies
Authors: Riaz Irbaz bin , Khan Muhammad Shahzeb , Mazursky Konstantin , Husnain Muhammad , Anwer Faiz 
Published: August 2017

ABSTRACT
This article describes a 71-year-old man with right knee pain, prerenal azotemia, hypercalcemia, and a mass in the distal femur. Although testing, including bone marrow biopsy, initially ruled out myeloma, an open surgical biopsy eventually confirmed the diagnosis as lymphoma involving the bone with classic histologic findings of mature B-cell neoplasm of germinal cell origin.
Female PAs—Where are we today?
Authors: Curtis L. Gail , Dobbs Lauren , Hildebrandt Carol A. 
Published: August 2017

ABSTRACT
As the physician assistant (PA) profession celebrates its 50th birthday, we can be proud of the gains our profession has accomplished. However, despite the positive reports of job satisfaction, a marked increase in female PA leaders, and overall gains in PA compensation, a significant wage gap remains between male and female PAs. The PA profession is flourishing but it is time female PAs are paid equitably.
Lessons learned from an in-flight medical event
Authors: Ngugi Mumbi Melody 
Published: August 2017

ABSTRACT
Air transportation, although safe, exposes passengers to distinct physical, psychological, and physiological stressors that may be well tolerated in a healthy passenger but may trigger or exacerbate a medical event in a passenger with underlying medical problems. This article describes how a medical provider on the flight assisted with a medical emergency on a transatlantic flight.
The officier de santé in 19th-century France
Authors: Perdicoyianni-Paleologou Helen 
Published: August 2017

ABSTRACT
In 1803, shortly after the French Revolution, the French healthcare system was reorganized and a new independent medical officer, the officier de santé (health officer) was introduced. Qualifications included 3 years in a medical school (compared with 6 years for a physician) and an apprenticeship with a physician. Although somewhat independent, officiers de santé were limited in their scope of practice to general medicine, prescribing medications, and minor surgical procedures. Many were deployed to medically underserved areas. After almost a century of activity in a role not unlike physician assistants, the officiers de santé were abolished in 1892. Development of a more rigorous medical education and an adequate supply of physicians meant that physicians were better deployed throughout France, and were largely the reasons for abolishing this PA prototype.
Malpositioned Pedicle Screw Compressed Thoracic Aorta of a Patient With Adolescent Idiopathic Scoliosis: Case Report and Literature Review
Authors: Ryabykh Sergey O. , Pavlova Olga M. , Savin Dmitry M. , Khomchenkov Maksim V. , Ochirova Polina V. , Hartmann Sebastian , Gubin Alexander V. 
Published: August 2017

Background:
Aortic injuries because of pedicle screw placement are quite rare, consequently management strategies to avoid vascular complications are lacking. Intraoperative or postoperative images to reveal the accuracy of screw placement in scoliotic misalignment with freehanded placed pedicle screws is therefore essential.

Case Report:
A 13-year-old girl with adolescent idiopathic scoliosis (AIS) was presented at the outpatient clinic of the authors department. Operative correction of the scoliotic misalignment including dorsal pedicle screw and rod placement with fusion from T3 to L4 was performed. Computed tomography scan after surgery showed left T9 screw malposition, accompanied by lateral compression of thoracic aorta. No clinical manifestations of aortic stenosis were noted. To avoid severe vascular complications, the thoracic screw was removed with the help of a specialized team of vascular as well as thoracic surgeons through extrapleural thoracotomy. After the removal of the malpositioned screw, the correction maneuvres were applied without the left T9 screw. No posttraumatic aortic aneurysm and other wall injury were identified after the revision surgery. The patient was discharged after 20 days of inpatient stay without the use external immobilization. The girl was in a good clinical condition after the 1-year follow-up visit without vascular or neurological complications.

Conclusions:
Malpositioned pedicle screws after dorsal correction in patients with adolescent idiopathic scoliosis might be challenging. Aortic injuries because of malpositioned screws are rare; nevertheless, the presence might be a life-threatening condition despite a clinical asymptomatic patient. As a consequence, the authors recommend to perform routine postoperative computed tomography scans combined with angiography in the case of significant lateral screw positioning.
Novel Interprofessional Mentoring Intervention to Improve Spirometry in Primary Care: Uptake, Feedback, and Effects on Behavioral Intention
Authors: Gupta Samir , Allen Christopher , Moosa Dilshad , MacPherson Ana , Tamari Itamar E. 
Published: August 2017

Introduction:
Little is known about the nature and effects of mentoring interventions on evidence-based clinician behaviors. We sought to design and evaluate a novel mentorship-based intervention to improve the usage of spirometry in primary care.

Methods:
This was a prospective one-year study of a pragmatic intervention across Canadian primary care sites. We established mentor–mentee pods, each including physician and nurse/allied health mentors and mentees, and enabled communication through a secure online portal; email; telephone; teleconference; videoconference; fax; and/or in person. We measured (1) change in intention to perform spirometry (through a questionnaire based on the theory of planned behavior, administered before and after the intervention); (2) mentoring uptake; and (3) feedback/satisfaction.

Results:
Twenty-five of 90 (28%) nurse/allied health and 23/68 (34%) physician mentees consented across seven sites. There were no statistically significant changes in behavioral intention after the intervention. Mentors logged 56.5 hours, with most preferred communication modalities being in person (6/11; 55%) and email (4/11; 36%). Mentees most commonly used email (9/18; 50%), followed by in-person communication (6/18; 33%). Mentees were highly satisfied with the experience, and most (89%) would participate in a similar program again.

Discussion:
A mentorship-based intervention can successfully engage physicians, nurses, and allied health practitioners through multiple communication platforms. Email seems to be an important medium for this activity. Such interventions can be highly satisfying and may affect certain constructs underlying mentees' behavioral intentions. Such a program can be replicated across diseases, and future research should measure effects on behavior, patient outcomes, and the sustainability of effects.
Utilization of Topographical Mohs Micrographic Surgery Maps for Rapid Review of Clinicopathologic Characteristics of Nonmelanoma Skin Cancers of the Ear
Authors: Tolkachjov Stanislav N. 
Published: August 2017

BACKGROUND
Nonmelanoma skin cancers (NMSCs) of the ear are considered high risk. Precise location of tumor sites is important when identifying surgical treatment sites.

OBJECTIVE
Review precise locations and histopathologic subtypes of auricular NMSC treated with Mohs micrographic surgery (MMS) using a standardized topographical numbering system for rapid data extraction.

MATERIALS AND METHODS
Using a MMS topographical number system, the author performed a retrospective chart review of 649 consecutive patients treated with MMS at Mayo Clinic for primary cutaneous basal cell carcinomas (BCCs) or squamous cell carcinomas (SCCs) of the ear.

RESULTS
Nineteen percent of consecutively referred patients had NMSC of the ear. Fifty-four percent were SCC and 42% were BCC. The left superior helix was the most common auricular location treated with MMS. Fifty-three percent of BCC on the ear were nodular. Seventy percent SCC on the ears were well differentiated. Contrary to previous studies, basosquamous carcinoma had strong predilection for the posterior ear (80%).

CONCLUSION
Higher incidence of auricular NMSC in men was confirmed with SCC being most common. Searching the medical record for specific topographical numbers allowed for rapid investigation of precise anatomic locations of NMSC. This technique may allow for focused research and rapid data extraction when anatomic location is the primary search criterion.
Triple Combination Therapy for Pincer Nail Deformity: Surgical Matricectomy, Thioglycolic Acid, and Anticonvex Sutures
Authors: Dikmen Adile , Ozer Kadri , Ulusoy Mustafa Gurhan , Gursoy Koray , Koçer Uğur 
Published: August 2017

BACKGROUND
Pincer nail deformity (PND) is characterized by an excessive transverse curvature of the nail plate that increases along the longitudinal axis of the nail. Although many conservative and surgical techniques have been used in clinical practice, an established consensus for the correction of PND has not been present yet.

OBJECTIVE
Aim of the technique described in this article is to provide to restore the suitable nail-matrix system curvature by a simplified and quick approach, which could be seen as a synthesis of conservative and surgical treatments described in the literature.

MATERIALS AND METHODS
Nineteen cases of pincer nail of the great toe in 14 patients were analyzed. After softening nail plate with 5% thioglycolic acid solution for at least half an hour, surgical bilateral matricectomy and 2 anticonvex sutures with 1-0 polypropylene were performed to ensure proper nail plate shape. Besides demographic data, visual analog scale (VAS) score for pain, width index, height index, patient and surgeon satisfaction scores, operation time, and the day of painless return to the daily activities were investigated.

RESULTS
A statistical significance was observed in VAS score for pain, width, and height indices between preoperative and postoperative values.

CONCLUSION
This report gives acceptable outcomes with a combination of surgery and conservative treatments.
Pathologists' Use of Second Opinions in Interpretation of Melanocytic Cutaneous Lesions: Policies, Practices, and Perceptions
Authors: Geller Berta M. , Frederick Paul D. , Knezevich Stevan R. , Lott Jason P. , Nelson Heidi D. , Titus Linda J. , Carney Patricia A. , Tosteson Anna N.A. , Onega Tracy L. , Barnhill Raymond L. , Weinstock Martin A. , Elder David E. , Piepkorn Michael W. , Elmore Joann G. 
Published: August 2017

BACKGROUND
Research examining the role of second opinions in pathology for diagnosis of melanocytic lesions is limited.

OBJECTIVE
To assess current laboratory policies, clinical use of second opinions, and pathologists' perceptions of second opinions for melanocytic lesions.

MATERIALS AND METHODS
Cross-sectional data collected from 207 pathologists in 10 US states who diagnose melanocytic lesions. The web-based survey ascertained pathologists' professional information, laboratory second opinion policy, use of second opinions, and perceptions of second opinion value for melanocytic lesions.

RESULTS
Laboratory policies required second opinions for 31% of pathologists and most commonly required for melanoma in situ (26%) and invasive melanoma (30%). In practice, most pathologists reported requesting second opinions for melanocytic tumors of uncertain malignant potential (85%) and atypical Spitzoid lesions (88%). Most pathologists perceived that second opinions increased interpretive accuracy (78%) and protected them from malpractice lawsuits (62%).

CONCLUSION
Use of second opinions in clinical practice is greater than that required by laboratory policies, especially for melanocytic tumors of uncertain malignant potential and atypical Spitzoid lesions. Quality of care in surgical interventions for atypical melanocytic proliferations critically depends on the accuracy of diagnosis in pathology reporting. Future research should examine the extent to which second opinions improve accuracy of melanocytic lesion diagnosis.
Orifice Preserving Double Opposing Z-Plasty for Partial Split Ear Lobe Repair: A Review of 25 Cases
Authors: Sharma Harish K. , Gupta Deepti , Punj Shalu 
Published: August 2017

BACKGROUND
Surgeons often come across split earlobe (SEL) deformities in their clinical practice which usually result from wearing heavy earrings for a long duration. It is of utmost importance to achieve a satisfactory repair with increased strength in one go.

OBJECTIVE
To describe a strong repair for partial SEL with preservation of the orifice.

MATERIALS AND METHODS
This study is a retrospective review of 25 patients (36 earlobes), who underwent repair of partial SEL deformity with an orifice preserving double opposing Z-plasty in the hospital, from January 2014 to June 2015. The duration of follow-up was 12 months.

RESULTS
Adequate cosmetic results were obtained in all patients with no need for revision surgery due to recurrence or scar dehiscence. Patients did not report any difficulty in wearing earrings and were satisfied with the aesthetic outcome.

CONCLUSION
The orifice preserving double opposing Z-plasty technique seems to offer an efficacious method of repair of partial SEL deformity with an acceptable scar. The technique is simple and reproducible with good aesthetic outcomes and minimal complications.
Chronic Uveitis Following Neodymium-Doped Yttrium Aluminum Garnet Laser Peripheral Iridotomy
Authors: Ali Amro , Rosenfeld Cyril , Rosenberg Eric , Sharma Sansar , Wandel Thaddeus L. 
Published: August 2017

Purpose:
Assessment of a chronic uveitis entity in nonuveitic patients following neodymium-doped yttrium aluminum garnet (Nd:YAG) laser peripheral iridotomy.

Methods:
A 7-year retrospective observational case series of 5 patients that developed chronic uveitis following a Nd:YAG laser peripheral iridotomy treatment.

Results:
Five eyes of 5 nonconsecutive patients had developed chronic anterior uveitis lasting >12 weeks. Four patients were female, with a mean age of 60.3 years (range, 48 to 83 y), and a mean follow-up duration of 8 months after initiation of treatment.

Conclusions:
Chronic anterior uveitis should be addressed as a possible risk in patients undergoing Nd:YAG laser iridotomies. A larger prospective study would be necessary in establishing and exploring the association between these 2 entities.
Age-Specific Antibiotic Prescribing and Adherence to Guidelines in Pediatric Patients in Primary Care
Authors: Ivanovska Verica , Hek Karin , Mantel-Teeuwisse Aukje K. , Leufkens Hubert G. M. , van Dijk Liset 
Published: August 2017

Background:
Most antibiotics in children are used to treat viral and self-limiting conditions. This study aims to compare physicians’ adherence to guidelines on antibiotic prescribing in fever and in ear and respiratory infections to children in different age groups in the Netherlands.

Methods:
Data were used from the NIVEL Primary Care Database. For all pediatric episodes of fever, acute otitis media (AOM), streptococcal pharyngitis (strep throat), sinusitis, acute tonsillitis, acute bronchitis/bronchiolitis and pneumonia in 2012, we determined whether national guidelines were followed with regard to whether an antibiotic was prescribed, and the type of antibiotic.

Results:
For diagnoses that generally do not require antibiotics, more prescriptions were found in adolescents’ episodes compared with children 0–4 and 5–11 years of age, respectively, (bronchitis: 52.0% versus 42.4% and 42.7%, and fever: 16.8% versus 9.0% and 14.2%). The same was true for diagnoses that require antibiotics (strep throat: 76.5% versus 55.0% and 49.5%, pneumonia: 71.6% versus 60.2% and 69.8% and tonsillitis: 57.8% versus 54.8% and 49.7%), except for AOM (43.9% versus 52.4% and 39.6%). First-choice amoxicillin was prescribed more frequently in children 0–4 years of age than in age groups 5–11 and 11–17 years (AOM: 88.0% versus 83.2% and 81.8%, and pneumonia:74.7% versus 57.2% and 53.8%). First-choice narrow-spectrum penicillins were prescribed more often in adolescents than in age groups 0–4 and 5–11 years (strep throat: 72.0% versus 63.6%, and 60.9% and tonsillitis: 67.9% versus 33.1 and 45.9%).

Conclusions:
Concerning adherence patterns include high antibiotic rates for bronchitis, particularly in adolescents, and underuse of narrow-spectrum penicillins in the 0–4 years group.
Beyond solicitousness: a comprehensive review on informal pain-related social support
Authors: Bernardes Sónia F. , Forgeron Paula , Fournier Karine , Reszel Jessica 
Published: August 2017

Abstract
Adults with chronic pain cite social support (SS) as an important resource. Research has mostly focused on general SS or pain-specific solicitousness, resulting in a limited understanding of the role of SS in pain experiences. Drawing on SS theoretical models, this review aimed to understand how pain-related SS has been conceptualized and measured and how its relationship with pain experiences has been investigated. Arksey and O'Malley scoping review framework guided the study. A database search (2000-2015) was conducted in PsycINFO, CINAHL, MEDLINE, and EMBASE using a combination of subject headings/keywords on pain and SS; 3864 citations were screened; 101 full texts were assessed for eligibility; references of 52 papers were hand searched. Fifty-three studies were included. Most studies were either a-theoretical or drew upon the operant conditioning model. There are several self-report measures and observational systems to operationalize pain-related SS. However, the Multidimensional Pain Inventory remains the most often used, accounting for the centrality of the concept of solicitousness in the literature. Most studies focused on individuals with chronic pain self-report of spousal pain-related SS and investigated its main effects on pain outcomes. Only a minority investigated the role of pain SS within the stress and coping process (as a buffer or mediator). Little is known about mediating pathways, contextual modulation of the effectiveness of SS exchanges, and there are practically no SS-based intervention studies. Drawing on general SS models, the main gaps in pain-related SS research are discussed and research directions for moving this literature beyond solicitousness are proposed.
Psychometric Properties of the 9-item European Heart Failure Self-care Behavior Scale Using Confirmatory Factor Analysis and Rasch Analysis Among Iranian Patients
Authors: Lin Chung-Ying , Pakpour Amir H. , Broström Anders , Fridlund Bengt , Årestedt Kristofer , Strömberg Anna , Jaarsma Tiny , Mårtensson Jan 
Published: August 2017

Background:
The 9-item European Heart Failure Self-Care Behavior scale (EHFScB-9) is a self-reported questionnaire commonly used to capture the self-care behavior of people with heart failure (HF).

Objective:
The aim of this study was to investigate the EHFScB-9’s factorial structure and categorical functioning of the response scale and differential item functioning (DIF) across subpopulations in Iran.

Methods:
Patients with HF (n = 380; 60.5% male; mean [SD] age, 61.7 [9.1] years) participated in this study. The median (interquartile range) of the duration of their HF was 6.0 (2.4–8.8) months. Most of the participants were in New York Heart Association classification II (NYHA II, 61.8%); few of them had left ventricular ejection fraction assessment (11.3%). All participants completed the EHFScB-9. Confirmatory factor analysis was used to test the factorial structure of the EHFScB-9; Rasch analysis was used to analyze categorical functioning and DIF items across 2 characteristics (gender and NYHA).

Results:
The 2-factor structure (“adherence to regimen” and “consulting behavior”) of the EHFScB-9 was confirmed, and the unidimensionality of each factor was found. Categorical functioning was supported for all items. No items displayed substantial DIF across gender (DIF contrast, −0.25–0.31). Except for item 3 (“Contact doctor or nurse if legs/feet are swollen”; DIF contrast, −0.69), no items displayed substantial DIF across NYHA classes (DIF contrast, −0.40 to 0.47).

Conclusions:
Despite the DIF displayed in 1 item across the NYHA classes, the EHFScB-9 demonstrated sound psychometric properties in patients with HF.
Venous Diverticula Causing Pulsatile Tinnitus Treated With Coil Embolization and Stent Placement With Resolution of Symptoms: Report of Two Cases and Review of the Literature
Authors: Shastri Ravi K. , Chaudhary Neeraj , Pandey Aditya S. , Telian Steven A. , Gemmete Joseph J. 
Published: August 2017

Objective:
To report two cases of pulsatile tinnitus caused by complex venous diverticula with successful treatment via coil embolization and stent placement followed by complete resolution of symptoms. We also review the literature pertaining to venous diverticula causing pulsatile tinnitus treated using endovascular techniques.

Patients:
Two women patients, aged 27 and 29 years, presented to our institution with 3-month histories of pulsatile tinnitus. In each case, non-invasive imaging and conventional digital subtraction angiography (DSA) confirmed the presence of a complex right transverse-sigmoid sinus junction diverticulum.

Intervention:
Both patients underwent stent-assisted coil embolization of the venous diverticula.

Main Outcome and Results:
Clinical and DSA follow-up at 6 and 12 months confirmed resolution of symptoms with obliteration of the venous diverticulum. We also performed a PubMed database search for the period January 1995 through June 2016 using the terms pulsatile tinnitus, venous aneurysm/diverticulum, stent-assisted coil embolization, and endovascular treatment and identified reports of 14 additional patients treated using endovascular techniques.

Conclusions:
Venous sinus diverticula causing pulsatile tinnitus can be successfully treated with stent-assisted coil embolization with complete resolution of clinical symptoms. This is in concordance with 13 case reports in the literature involving 14 patients with venous sinus diverticula treated using endovascular techniques.
Impact of Insurance Status and Race on Outcomes in Nonvariceal Upper Gastrointestinal Hemorrhage
Authors: Abougergi Marwan S. , Avila Patrick , Saltzman John R. 
Published: August 2017

Background and Goals:
We examined the interaction between race, insurance, and important outcomes in nonvariceal upper gastrointestinal hemorrhage (NVUGIH).

Study:
Adults with NVUGIH were selected from the National Inpatient Sample. Primary outcome: in-hospital mortality. Secondary outcomes: treatment modalities [esophagogastroduodenoscopy (EGD), early EGD, and endoscopic or radiologic therapy], and resource utilization (length of hospital stay and total hospitalization charges).

Results:
Mortality was similar for Medicare and private insurance [adjusted odds ratios (aOR): 1.15 95% confidence interval (CI) 0.90 to 1.47), P=0.24], but higher for under/uninsured patients [aOR: 1.84 (CI: 1.42 to 2.40), P<0.01]. Compared with Medicare, patients with private insurance had more EGDs [aOR: 1.35 (CI: 1.23 to 1.48), P<0.01], early EGDs [aOR: 1.29 (CI: 1.21 to 1.38), P<0.01], and endoscopic [aOR: 1.19 (CI: 1.11 to 1.27), P<0.01], or radiologic therapy [aOR:1.35 (CI: 1.06 to 1.71), P=0.01]. Patients who were under/uninsured had less EGDs [aOR: 0.84 (CI: 0.76 to 0.91), P<0.01] or endoscopic therapy [aOR: 0.74 (CI: 0.68 to 0.81), P<0.01], but similar odds of early EGD [aOR: 0.95 (CI: 0.88 to 1.02), P=0.13] or radiologic therapy [aOR: 1.01 (CI: 0.75 to 1.37), P=0.75]. Compared with whites, blacks had lower [aOR: 0.73 (CI: 0.58 to 0.93), P=0.01] and Native Americans higher mortality [aOR: 2.60 (CI: 1.57 to 4.13), P<0.01]. Blacks were less likely [aOR: 0.86 (CI: 0.79 to 0.94), P<0.01] and Asians more likely [aOR: 1.24 (CI: 1.05 to 1.47), P=0.01] to have EGDs. Both blacks and Hispanics had lower, whereas Asians had higher early EGD rates. Patients with private insurance had lower total charges [adjusted mean difference: −$2761 (CI: −$4617 to −$906), P<0.01].

Conclusions:
Insurance and race have independent effects on NVUGIH mortality, therapeutic modalities used, and resource utilization. Black and under/uninsured patients have the worst outcomes.