bluuebunny/crossref_metadata_2025_split huggingface dataset:
Internet researchers’ data sharing behaviors
Authors: Kim Youngseek , Nah Seungahn 
Published: November 2017

Purpose
The purpose of this paper is to examine how data reuse experience, attitudinal beliefs, social norms, and resource factors influence internet researchers to share data with other researchers outside their teams.

Design/methodology/approach
An online survey was conducted to examine the extent to which data reuse experience, attitudinal beliefs, social norms, and resource factors predicted internet researchers’ data sharing intentions and behaviors. The theorized model was tested using a structural equation modeling technique to analyze a total of 201 survey responses from the Association of Internet Researchers mailing list.

Findings
Results show that data reuse experience significantly influenced participants’ perception of benefit from data sharing and participants’ norm of data sharing. Belief structures regarding data sharing, including perceived career benefit and risk, and perceived effort, had significant associations with attitude toward data sharing, leading internet researchers to have greater data sharing intentions and behavior. The results also reveal that researchers’ norms for data sharing had a direct effect on data sharing intention. Furthermore, the results indicate that, while the perceived availability of data repository did not yield a positive impact on data sharing intention, it has a significant, direct, positive impact on researchers’ data sharing behaviors.

Research limitations/implications
This study validated its novel theorized model based on the theory of planned behavior (TPB). The study showed a holistic picture of how different data sharing factors, including data reuse experience, attitudinal beliefs, social norms, and data repositories, influence internet researchers’ data sharing intentions and behaviors.

Practical implications
Data reuse experience, attitude toward and norm of data sharing, and the availability of data repository had either direct or indirect influence on internet researchers’ data sharing behaviors. Thus, professional associations, funding agencies, and academic institutions alike should promote academic cultures that value data sharing in order to create a virtuous cycle of reciprocity and encourage researchers to have positive attitudes toward/norms of data sharing; these cultures should be strengthened by the strong support of data repositories.

Originality/value
In line with prior scholarship concerning scientific data sharing, this study of internet researchers offers a map of scientific data sharing intentions and behaviors by examining the impacts of data reuse experience, attitudinal beliefs, social norms, and data repositories together.
Mechanical properties and water absorption of surface modified ABS 3D printed by fused deposition modelling
Authors: Leite Marco , Varanda André , Ribeiro António Relógio , Silva Arlindo , Vaz Maria Fátima 
Published: November 2017

Purpose
The purpose of this paper is to investigate the effect of a sealing protective treatment on the water absorption and mechanical properties of acrylonitrile butadiene styrene (ABS)-printed parts by fused deposition modelling. Protective products include aqueous acetone solutions with different concentrations, polyurethane wood sealer and aqueous acrylic-based varnish.

Design/methodology/approach
Open porosity was estimated by the absorption coefficient and the total amount of water retained, obtained from water absorption tests. Mechanical characterization was performed by compressive and tensile tests. Different specimens with different build directions and raster angles were used.

Findings
The treatments with acetone solutions were not effective in reducing the porosity of ABS parts, as the amount of acetone that reduces effectively the porosity will also affect the sample dimensional stability. The polyurethane treatment was found to reduce the absorption coefficient, but the maximum water content and the open porosity remain almost unchanged in comparison with the ones obtained for untreated specimens. The treatment with an acrylic-based varnish was found to preserve the dimensional stability of the specimens, to reduce the open porosity and to maintain the compression and tension properties of the specimens in different build directions and raster angles.

Originality/value
Surface modification for water tight applications of ABS 3D printing parts enables new designs where both sealing and the preservation of mechanical properties are important. As per the knowledge of the authors, the water absorption and the mechanical behaviour of ABS 3D printed parts, before and after treatment, were not previously investigated.
The Determinants of Foreign Currency Debt Financing: Borrower Incentives or Lender Incentives?
Authors: Bae Sung C. , Kim Hyeon Sook , Kwon Taek Ho 
Published: November 2017

AbstractWe offer new evidence that firm‐level determinants of foreign currency (FC) and local currency (LC) debt financing differ significantly. WhileLCdebt financing is affected mainly by demand‐side borrower incentives, such as operating profitability, financing deficit, and depreciation expenses that reflect borrowers' capital needs,FCdebt financing is affected mostly by supply‐side lender incentives, such as tangible assets, firm size, asset growth, and R&D expenses, whichFCdebt lenders consider in assessing the potential value of collateral, in addition to the widely‐reported export ratio. Our results remain robust in the presence of macro‐level factors.
Intravascular ultrasound of the proximal left anterior descending artery is sufficient to detect early cardiac allograft vasculopathy
Authors: Floré Vincent , Brown Adam J. , Pettit Stephen J. , West Nick E. J. , Lewis Clive , Parameshwar Jayan , Hoole Stephen P. 
Published: November 2017

AbstractObjectiveCardiac allograft vasculopathy (CAV) can be detected early with intravascular ultrasound (IVUS), but there is limited information on the most efficient imaging protocol.MethodsCoronary angiography and IVUS of the three coronary arteries were performed. Volumetric IVUS analysis was performed, and a Stanford grade determined for each vessel.ResultsEighteen patients were included 18 (range 12‐24) months after transplantation. Angiographic CAV severity ranged from none (CAV0) to mild (CAV1), whereas IVUS CAV severity ranged from none (Stanford grade I) to severe (grade IV). Maximal intimal thickness measured with IVUS was significantly greater in the LAD (0.84 ± 0.48 mm) than in the LCX (0.46 ± 0.32 mm) or the RCA (0.53 ± 0.41 mm, P = .005). Diagnostic accuracy of IVUS in the left anterior descending artery was 100% (18 of 18 Stanford grades matched the patient's highest overall Stanford grade), 66% in the right coronary artery (12 of 18), and 56% in the left circumflex artery (11 of 18). The minimal required length of left anterior descending artery pullbacks to attain 100% accuracy was 36 mm (range 3‐36 mm) distal from the guide catheter ostium.ConclusionsThese data suggest that focal IVUS imaging of the proximal LAD followed by volumetric analysis may suffice when screening for transplant vasculopathy.
Parasites favour intermediate nestling mass and brood size in cliff swallows
Authors: Brown Charles R. , Brown Mary Bomberger 
Published: November 2017

AbstractA challenge of life‐history theory is to explain why animal body size does not continue to increase, given various advantages of larger size. In birds, body size of nestlings and the number of nestlings produced (brood size) have occasionally been shown to be constrained by higher predation on larger nestlings and those from larger broods. Parasites also are known to have strong effects on life‐history traits in birds, but whether parasitism can be a driver for stabilizing selection on nestling body size or brood size is unknown. We studied patterns of first‐year survival in cliff swallows (Petrochelidon pyrrhonota) in western Nebraska in relation to brood size and nestling body mass in nests under natural conditions and in those in which hematophagous ectoparasites had been removed by fumigation. Birds from parasitized nests showed highest first‐year survival at the most common, intermediate brood‐size and nestling‐mass categories, but cliff swallows from nonparasitized nests had highest survival at the heaviest nestling masses and no relationship with brood size. A survival analysis suggested stabilizing selection on brood size and nestling mass in the presence (but not in the absence) of parasites. Parasites apparently favour intermediate offspring size and number in cliff swallows and produce the observed distributions of these traits, although the mechanisms are unclear. Our results emphasize the importance of parasites in life‐history evolution.
Better to be resident, larger or coloured? Experimental analysis on intraspecific aggression in the ruin lizard
Authors: Titone V. , Marsiglia F. , Mangiacotti M. , Sacchi R. , Scali S. , Zuffi M. A. L. 
Published: November 2017

AbstractTerritoriality evolves when the benefits gained from exclusive access to limited resources exceed the costs of defence. Sometimes animals evolve distinct morphs, that may reflect different capability, and in some territorial species of lizards the polymorphism is associated to alternative strategies, both for reproductive efficiency and territorial dominance. It is known that normally larger males are more aggressive and are able to defend a larger area and for longer than small males; in fact this dynamic is widespread in many animal species including the genusPodarcis. The aim of our study was to test which factors determine the outcome of fighting in the strongly territorial Italian ruin lizard,Podarcis siculus, using two types of contests: (1) resident versus intruder and (2) in a neutral arena. Furthermore, because these lizards are characterized by strong ventral colour variability, usually restricted to jaws and throat, we wanted to investigate if coloured lizards have higher chances at winning than white lizards. The results showed that the fight's result was significantly influenced by the state of residence, while the colour had no effect; instead, the snout to vent length difference between opponents had significant influence on the outcome in the neutral arena. Our results suggest that, in this lizard, both the size and the state of residency, no matter of colour, play an important role to determine the outcome of a fight, however, highly depending on the contest. We think thatP. siculusshould be object of future studies, focusing on behavioural and ecological aspects, even considering the occurrence of different colours within and among populations.
Vectorial status of the Asian tiger mosquito Aedes albopictus of La Réunion Island for Zika virus
Authors: VAZEILLE M. , DEHECQ J.‐S. , FAILLOUX A.‐B. 
Published: November 2017

AbstractLa Réunion Island has been the scene of unusually large epidemics of dengue (DENV) and chikungunya (CHIKV) viruses with Aedes albopictus Diptera, Culicidae (Skuse, 1894) as the sole vector. The emergence of Zika virus (ZIKV) in 2007 and the spread of the epidemic strain of the Asian genotype through the Pacific region and the Americas, mainly via the vector Aedes aegypti (Linnaeus, 1762), has raised concern about its possible introduction to, and transmission in, Ae. albopictus‐infested areas. We performed an experimental oral infection with the Asian genotype of ZIKV in Ae. albopictus from La Réunion and found a strong midgut barrier to dissemination. This result is discussed in the light of previous vector competence assays for DENV and CHIKV performed by our team on other Ae. albopictus populations from La Réunion.
Description of the periodontal pocket in preclinical models: limitations and considerations
Authors: Donos Nikolaos , Park Jung‐Chul , Vajgel André , de Carvalho Farias Bruna , Dereka Xanthippi 
Published: November 2017

AbstractEstablishment of periodontal health and regeneration of the lost periodontal tissues are always the ultimate goal of periodontal treatment. The development of new therapeutic approaches raises the necessity for appropriate experimental models that present periodontal structures and healing capability comparable to humans. Preclinical research and extrapolation of the data to human conditions remains a stage of great importance before the clinical application of the new biomaterials and techniques. Periodontal pockets/defects in preclinical models can be induced experimentally through acute or chronic or a combination of both (induced) modalities. The features of the created defects and those of humans vary greatly mostly due to the nature of the periodontal disease. This is an important point to take into account, since it is well recognized that the potential of periodontal therapy may be dependent on both the biological background and the defect morphology. This review provides insight into the commonly used preclinical models for the reproduction of the periodontal pocket and discusses the advantages and disadvantages of each model in terms of similarity to human conditions, standardization and reproducibility.
High Performance Computing and Analysis-Led Development of High Efficiency Dilute Opposed Piston Gasoline Engine
Authors: Banerjee Siddhartha , Naber Clayton , Willcox Michael , Finney Charles E. A. , Edwards K. Dean 
Published: November 2017

Pinnacle is developing multi-cylinder 1.2 L gasoline engine for automotive applications using high performance computing (HPC) and analysis methods. Pinnacle and Oak Ridge National Laboratory executed large-scale multi-dimensional combustion analyses at the Oak Ridge Leadership Computing Facility to thoroughly explore the design space. These HPC-led investigations show high fuel efficiency (∼46% gross indicated efficiency) may be achieved by operating with extremely high charge dilution levels of exhaust gas recirculation (EGR) at a light load key drive cycle condition (2000 RPM, 3 bar BMEP), while simultaneously attaining high levels of fuel conversion efficiency and low NOx emissions. In this extremely dilute environment, the flame propagation event is supported by turbulence and bulk in-cylinder charge motion brought about by modulation of inlet port flow. This arrangement produces a load and speed adjustable amalgamation of swirl and counter-rotating tumble which provides the turbulence required to support stable low-temperature combustion (LTC). At higher load conditions, the engine may operate at more traditional combustion modes to generate competitive power.
In this paper, the numerical results from these HPC simulations are presented. Further HPC simulations and test validations are underway and will be reported in future publications.
Impact of training state on fasting-induced regulation of adipose tissue metabolism in humans
Authors: Bertholdt Lærke , Gudiksen Anders , Stankiewicz Tomasz , Villesen Ida , Tybirk Jonas , van Hall Gerrit , Bangsbo Jens , Plomgaard Peter , Pilegaard Henriette 
Published: November 2017

Recruitment of fatty acids from adipose tissue is increased during fasting. However, the molecular mechanisms behind fasting-induced metabolic regulation in human adipose tissue and the potential impact of training state in this are unknown. Therefore the aim of the present study was to investigate 1) fasting-induced regulation of lipolysis and glyceroneogenesis in human adipose tissue as well as 2) the impact of training state on basal oxidative capacity and fasting-induced metabolic regulation in human adipose tissue. Untrained [maximal oxygen uptake (V̇o2max) < 45 ml·min−1·kg−1] and trained subjects (V̇o2max> 55 ml·min−1·kg−1) fasted for 36 h, and abdominal subcutaneous adipose tissue biopsies were obtained 2, 12, 24, and 36 h after a standardized meal. Adipose tissue oxidative phosphorylation complexes, phosphoenolpyruvate carboxykinase, and pyruvate dehydrogenase (PDH)-E1α protein as well as PDH kinase (PDK) 2, PDK4, and PDH phosphatase 2 mRNA content were higher in trained subjects than in untrained subjects. In addition, trained subjects had higher adipose tissue hormone-sensitive lipase Ser660 phosphorylation and adipose triglyceride lipase protein content as well as higher plasma free fatty acid concentration than untrained subjects during fasting. Moreover, adipose tissue PDH phosphorylation increased with fasting only in trained subjects. Taken together, trained subjects seem to possess higher basal adipose tissue oxidative capacity as well as higher capacity for regulation of lipolysis and for providing substrate for glyceroneogenesis in adipose tissue during fasting than untrained subjects.NEW & NOTEWORTHY This study shows for the first time higher protein content of lipolytic enzymes and higher oxidative phosphorylation protein in adipose tissue from trained subjects than from untrained subjects during fasting. Furthermore, trained subjects had higher capacity for adipose tissue glyceroneogenesis than untrained subjects.
Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury
Authors: Le Bras Alexandra , Yu Baoqi , Issa Bhaloo Shirin , Hong Xuechong , Zhang Zhongyi , Hu Yanhua , Xu Qingbo 
Published: November 2017

Objective—

Vascular adventitial Sca1
+
(stem cell antigen-1) progenitor cells preferentially differentiate into smooth muscle cells, which contribute to vascular remodeling and neointima formation in vessel grafts. Therefore, directing the differentiation of Sca1
+
cells toward the endothelial lineage could represent a new therapeutic strategy against vascular disease.

Approach and Results—

We thus developed a fast, reproducible protocol based on the single-gene transfer of ETV2 (ETS variant 2) to differentiate Sca1
+
cells toward the endothelial fate and studied the effect of cell conversion on vascular hyperplasia in a model of endothelial injury. After ETV2 transduction, Sca1
+
adventitial cells presented a significant increase in the expression of early endothelial cell genes, including
VE-cadherin
,
Flk-1
, and
Tie2
at the mRNA and protein levels. ETV2 overexpression also induced the downregulation of a panel of smooth muscle cell and mesenchymal genes through epigenetic regulations, by decreasing the expression of DNA-modifying enzymes ten-eleven translocation dioxygenases. Adventitial Sca1
+
cells grafted on the adventitial side of wire-injured femoral arteries increased vascular wall hyperplasia compared with control arteries with no grafted cells. Arteries seeded with ETV2-transduced cells, on the contrary, showed reduced hyperplasia compared with control.

Conclusions—
These data give evidence that the genetic manipulation of vascular progenitors is a promising approach to improve vascular function after endothelial injury.
Prognostic Value of Serial Galectin‐3 Measurements in Patients With Acute Heart Failure
Authors: van Vark Laura C. , Lesman‐Leegte Ivonne , Baart Sara J. , Postmus Douwe , Pinto Yigal M. , de Boer Rudolf A. , Asselbergs Folkert W. , Wajon Elly M. C. J. , Orsel Joke G. , Boersma Eric , Hillege Hans L. , Akkerhuis K. Martijn , Nagelsmit Michiel J. , Brunner‐La Rocca Hans‐Peter , Linssen Gerard C.M. , Terpstra Willem F. , Liem Anho H. , Wardeh Alexander J. , van Miltenburg Addy J.M. , van den Bos Ewout J. , de Ridder Stijn P.J. 
Published: November 2017

Background

Several clinical studies have evaluated the association between galectin‐3 levels and outcome in patients with heart failure (
HF
). However, little is known about the predictive value of repeated galectin‐3 measurements. This study evaluates the prognostic value of repeated time‐dependent galectin‐3 measurements in acute
HF
patients.

Methods and Results

In the
TRIUMPH
(Translational Initiative on Unique and Novel Strategies for Management of Patients with Heart Failure) clinical cohort study, 496 acute
HF
patients were enrolled in 14 hospitals in The Netherlands, between 2009 and 2014. Repeated blood samples (7) were drawn during 1‐year follow‐up. Associations between repeated biomarker measurements and the primary end point were assessed using a joint model. Median age was 74 years and 37% were women. The primary end point, composite of all‐cause mortality and
HF
rehospitalization, was reached in 188 patients (40%), during a median follow‐up of 325 days (interquartile range 85–401). The median baseline galectin‐3 level was 24 ng/mL (interquartile range 18–34). The mean number of galectin‐3 measurements available per patient was 4.3. After adjustment for clinical factors and N‐terminal pro‐brain natriuretic peptide, there was a weak association between baseline galectin‐3 and risk of the primary end point. When repeated measurements were taken into account, the adjusted hazard ratio per 1 SD increase of the galectin‐3 level (on the log2 scale) at any time point increased to 1.67 (95% confidence interval, 1.24–2.23,
P
<0.001). After additional adjustment for repeated N‐terminal pro‐brain natriuretic peptide measurements, the association remained statistically significant.

Conclusions

Repeated galectin‐3 measurements appeared to be a strong predictor of outcome in acute
HF
patients, independent of N‐terminal pro‐brain natriuretic peptide. Hence, galectin‐3 may be helpful in clinical practice for prognostication and treatment monitoring.
Long-Term Effect of Pravastatin on Carotid Intima–Media Complex Thickness
Authors: Koga Masatoshi , Toyoda Kazunori , Minematsu Kazuo , Yasaka Masahiro , Nagai Yoji , Aoki Shiro , Nezu Tomohisa , Hosomi Naohisa , Kagimura Tatsuo , Origasa Hideki , Kamiyama Kenji , Suzuki Rieko , Ohtsuki Toshiho , Maruyama Hirofumi , Kitagawa Kazuo , Uchiyama Shinichiro , Matsumoto Masayasu 
Published: November 2017

Background and Purpose—
The effect of statins on progression of carotid intima–media complex thickness (IMT) has been shown exclusively in nonstroke Western patients. This study aimed to determine the effect of low-dose pravastatin on carotid IMT in Japanese patients with noncardioembolic ischemic stroke.

Methods—
This is a substudy of the J-STARS trial (Japan Statin Treatment Against Recurrent Stroke), a multicenter, randomized, open-label, parallel-group trial to examine whether pravastatin reduces stroke recurrence. Patients were randomized to receive pravastatin (10 mg daily, usual dose in Japan; pravastatin group) or not to receive any statins (control group). The primary outcome was IMT change of the common carotid artery for a 5-year observation period. IMT change was compared using mixed-effects models for repeated measures.

Results—

Of 864 patients registered in this substudy, 71 without baseline ultrasonography were excluded, and 388 were randomly assigned to the pravastatin group and 405 to the control group. Baseline characteristics were not significantly different, except National Institutes of Health Stroke Scale scores (median, 0 [interquartile range, 0–2] versus 1 [interquartile range, 0–2];
P
=0.019) between the 2 groups. Baseline IMT (mean±SD) was 0.887±0.155 mm in the pravastatin group and 0.887±0.152 mm in the control group (
P
=0.99). The annual change in the IMT at 5-year visit was significantly reduced in the pravastatin group as compared with that in the control group (0.021±0.116 versus 0.040±0.118 mm;
P
=0.010).

Conclusions—
The usual Japanese dose of pravastatin significantly reduced the progression of carotid IMT at 5 years in patients with noncardioembolic stroke.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT00361530.