bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: DE NOVO SYNTHESIS OF CARBOHYDRATES AND CONVERTED NATURAL SUBSTANCES. PART 8. HETERO DIELS‐ALDER REACTIONS FOR SYNTHESIS OF THROMBOXANE INTERMEDIATES
Authors: SCHMIDT R. R. , ABELE W. 
Published: April 2016

AbstractDie Cycloadditionsreaktion des (Z.E)‐1‐Methoxy‐1,3‐hexadiens (I), das am C(4) den erforderlichen C2 ‐Substituenten enthält, mit dem Ester (II) als reaktivem Dienophil ergibt ein Gemisch der Pseudoglycaluronate (III), (IV) und (V), das säulenchromatographisch getrennt werden kann.
ChemInform Abstract: RADICAL IONS. 48. RADICAL ANIONS AS INTERMEDIATES IN THE REDUCTIVE DESULFURIZATION OF TERTIARY PHOSPHINE SULFIDES
Authors: KAIM W. , HAENEL P. + , LECHNER‐KNOBLAUCH U. , BOCK H. 
Published: April 2016

AbstractDimethylthiophosphinyl‐Gruppen, ‐P(S)Me2 , wirken gegenüber π‐Systemen wie in (I) als Akzeptorsubstituenten.
ChemInform Abstract: Some Novel Reactions of 1,3‐Dimethyluracils. Part 2. Studies on New Stable Pyrimidine Ring‐Opened Compounds.
Authors: KAWAHARA N. , ITO T. , OGURA H. , WATANABE K. A. 
Published: April 2016

AbstractDie Chloruracile (I) reagieren mit sekundären Aminen (II) zu den Aminouracilen (III), die mit Acetylendicarbonsäuredimethylester (IV) zu den O,N‐Ketenacetalen (V) reagieren.
ChemInform Abstract: INTRAMOLECULAR PHOTOCHEMICAL CYCLOADDITION REACTIONS OF 3‐(1,5‐DIMETHYLHEX‐4‐ENYL) CYCLOHEX‐2‐ENONE: REGIO‐ AND STEREOCHEMICAL ASPECTS
Authors: HOYE T. R. , MARTIN S. J. , PECK D. R. 
Published: April 2016

AbstractAus den Hexenylcyclohexenonen (I) erhält man bei der Photolyse die Cyclisierungsprodukte (II) und (III).
ChemInform Abstract: NON‐STEROIDAL ANTIINFLAMMATORY AGENTS. 8. METHANESULFONANILIDES. III
Authors: RUFER C. , BAHLMANN F. , SCHROEDER E. + , BOETTCHER I. + 
Published: April 2016

AbstractDie Indanone (V) zeigen eine starke entzündungshemmende Aktivität, die derjenigen der entsprechenden N‐Indanyl‐methansulfonamide mit nicht substituiertem Fünfring vergleichbar ist (in einigen Fällen wird die Wirkung des Indomethacins erreicht oder sogar übertroffen).
ChemInform Abstract: THERMALLY STABLE SULFENIC ACID: (3R,4R)‐1‐(TERT‐BUTYLDIMETHYLSILYL)‐3‐PHTHALIMIDO‐2‐OXO‐AZETIDINE‐4‐SULFENIC ACID
Authors: BACHI M. D. , GROSS A. 
Published: April 2016

AbstractDas β‐Iactam‐sulfoxid (I) wird mit Trifluoracetanhydrid und Natriumiodid zum Sulfid (IIa) reduziert, am Stickstoff zu (IIb) silyliert und erneut mit Persäure zum S‐Oxid (III) oxidiert, dessen Stereoisomere getrennt und zugeordnet werden.
ChemInform Abstract: OXIDATION OF N‐HYDROXYAZETIDINES: A NOVEL SYNTHESIS OF N‐ACETOXY β‐LACTAMS AND FOUR‐MEMBERED CYCLIC NITRONES
Authors: PENNINGS M. L. M. , REINHOUDT D. N. 
Published: April 2016

AbstractAus den cyclischen Nitronen (I) entstehen bei der Reduktion mit Boranat die N‐Hydroxy‐Verbindungen (II), die mit HgO wieder zu (I) oxidiert werden können.
ChemInform Abstract: MULTISTAGE REACTIONS WITH PARTICIPATION OF LATENT α‐HETERO‐SUBSTITUTED CARBANIONS: REACTION OF 2‐PYRROLECARBOXALDEHYDE WITH 1,2‐DISUBSTITUTED ETHENES
Authors: FLITSCH W. , LUBISCH W. 
Published: April 2016

AbstractUntersuchungen zeigen, daß die Umsetzungen der 1,2‐bisheterostabilisierten Ethene (II) mit dem Anion von 2‐Pyrrolcarbaldehyd (I) zu den Pyrrolizin‐Derivaten (III) (ist X = PPh3) oder dem Pyrrolo[ 1 ′,2′:3,4]pyrimido[2,l ,6‐cd]pyrrolizin (IVa) und/oder (IVb) 9l oder (IVb) und dem Pyrrolizin‐Derivat (V) führen.
ChemInform Abstract: STUDIES ON THE SYNTHESIS OF HETEROCYCLIC AND NATURAL COMPOUNDS. CMXLV. A STEREOSELECTIVE SYNTHESIS OF NON‐TRYPTAMINE COMPONENTS OF RESERPINE AND YOHIMBINE FROM FURFURAL
Authors: KAMETANI T. , SUZUKI T. , TOMINO A. , UNNO K. 
Published: April 2016

AbstractDas Diels‐Alder‐Addukt (III) aus Maleinsäureanhydrid (I) und dem Ethylenacetal des Furancarboxaldehyds (II) geht nach Hydrolyse und ′Zusatz von Brom in ein Gemisch der beiden Lactone (IV) und (V) über.
ChemInform Abstract: TOTAL SYNTHESIS OF (.+‐.)‐ISO‐β‐PELTATIN AND ITS ANALOGS
Authors: BROWN E. , LORIOT M. , ROBIN J.‐P. 
Published: April 2016

AbstractDie Synthese von (+)‐Iso‐β‐peltatin‐Derivaten der Art (X) wird beschrieben.
ChemInform Abstract: REACTIONS OF SPIRO(FLUORENETRIAZOLINES)
Authors: HIRAKAWA K. , TANABIKI Y. 
Published: April 2016

Abstract9‐Methylen‐fluoren (Ia) reagiert mit Arylaziden (II) zu den spirocyclischen Triazolen (III), die thermisch, sauer oder photolytisch in die Arylamino‐phenanthrene (IV) umgewandelt werden.
ChemInform Abstract: 1,2,3‐TRIAZOLO(1,5)AZINES AND OTHER NITROGEN HETEROCYCLES DERIVED FROM AZINECARBOXALDEHYDES
Authors: MAURY G. , MEZIANE D. , SRAIRI D. , PAUGAM J.‐P. , PAUGAM R. 
Published: April 2016

AbstractDer Carboxaldehyd (I) läßt sich über das Hydrazon (II) und dessen Oxida‐ tion zum Triazolopyrazin (III) cyclisieren.
ChemInform Abstract: STUDY OF THE HYDROLYSIS OF 1‐OXO‐3‐ETHYL‐4‐ARYL‐2,3‐BENZOXAZINIUM SALTS
Authors: VOLYNETS N. F. , SAMARTSEVA I. V. , PAVLOVA L. A. 
Published: April 2016

AbstractDie 4‐Aryl‐ (bzw. 4‐Methyl‐)benzoxazoline (I) werden mit Et3OBF4 unter N‐Alkylierung zu den entsprechenden Tetrafluoroboraten (II) umgesetzt, aus denen leicht die Perchlorate (III) bzw. die Tetrachloroferrate (IV) erhalten werden.
ChemInform Abstract: COMPLEX FORMATION BY ALKYLATING OR ARYLATING ORGANOMETALLIC COMPOUNDS
Authors: ROESKY H. W. , SCHOENFELDER L. + 
Published: April 2016

AbstractDie Schwefeldiimide (I) reagieren mit den metallorganischen Verbindungen (II) zu den 1:1‐Addukten (III), während mit PbPh4 (IV) und (Ia) durch Addition an beide Doppelbindungen ein Ring (V) gebildet wird.
ChemInform Abstract: COORDINATION CHEMISTRY OF FUNCTIONAL PHOSPHORUS YLIDES. PART 1. 2‐METHYL‐2‐TRIPHENYLPHOSPHONIODITHIOPROPIONATE ‐ A PHOTOSENSITIVE COMPLEX LIGAND WITH UNSTABLE PHOSPORUS‐CARBON BONDING
Authors: KUNZE U. , MERKEL R. , WINTER W. 
Published: April 2016

AbstractDie Umsetzung des stabilen Betain‐Liganden (II) mit Halogenopentacarbonyl‐Mn (Ia) unter striktem Lichtausschluß führt zu den lichtempfindlichen fac‐Tricarbonyl‐ Komplexen (IIIa), die durch Laserstrahlung spontan zersetzt werden.
ChemInform Abstract: BIOINORGANIC APPROACH TO THE TYPE‐I AND TYPE‐II COPPER PROTEINS. SYNTHESIS AND PROPERTIES OF COPPER(II) COMPLEXES WITH TRIPOD‐LIKE LIGANDS CONTAINING THRE OR FOUR DONOR SPECIES
Authors: TAKAHASHI K. , OGAWA E. , OISHI N. , NISHIDA Y. , KIDA S. 
Published: April 2016

AbstractDurch Umsetzung von 2‐Chlormethyl‐4‐nitrophenol bzw. 2‐ Chlormethylbenzimidazol mit den entsprechenden Aminen in siedendem THF werden die tripoden‐ähnlichen Liganden dargestellt.
ChemInform Abstract: PREPARATION, CHARACTERIZATION AND CRYSTAL STRUCTURE OF TETRAKIS(1‐METHYLIMIDAZOLINE‐2(3H)‐THIONE)PLATINUM(II) DICHLORIDE DIHYDRATE
Authors: O'NEILL M. E. , RAPER E. S. , DANIELS J. A. , NOWELL I. W. 
Published: April 2016

AbstractDas durch 1:4‐molare Umsetzung von Pt‐chlorid und N‐Methylimidazolin‐2(3H)‐thion in siedendem Ethanol gebildete, als Dihydrat isolierte Produkt wird als dikationischer quadratisch‐planarer Komplex (I) identifiziert, in dem die Liganden über ihre S‐Atome koordiniert sind.
ChemInform Abstract: NEW SYNTHESES OF OCTAALKYL‐ AND OCTAISOALKYLPORPHYRINS
Authors: CALLOT H. J. , LOUATI A. , GROSS M. 
Published: April 2016

AbstractAusgehend von den Alkenylethylethern (I) wird in einer einfachen Reaktionsfolge unter Ausnutzung der Symmetrie der Produkte und ihrer Vorstufen außer den Oktaalkylverbindungen (Va) und (Vb) erstmals ein Isopropylderivat (Vc) dargestellt.
ChemInform Abstract: DESIGN OF MORE POTENT ANTAGONISTS OF THE ANTIDIURETIC RESPONSES TO ARGININE‐VASOPRESSIN
Authors: MANNING M. , OLMA A. , KLIS W. A. , KOLODZIEJCZYK A. M. , SETO J. , SAWYER W. H. 
Published: April 2016

AbstractDargestellt und als antidiuretische Antagonisten untersucht werden die Analoga (I).
ChemInform Abstract: TOTAL SYNTHESIS OF (.+‐.)‐OUDEMANSIN
Authors: NAKATA T. , KUWABARA T. , TANI Y. , OISHI T. 
Published: April 2016

Abstracttrans‐Zimtaldehyd (I) reagiert mit Brom‐propionsäuremethylester in Gegenwart von Zn zu den beiden isomeren Verbindungen (IIa) und (IIb), die mit Pyridiniumdichromat (PDC) zum Ketoester (III) oxidiert werden.
ChemInform Abstract: A CERIUM‐NIOBIUM‐(ALUMINUM) OXIDE POROUS GLASS‐CERAMIC
Authors: RES M. A. , FOURIE J. T. , WHITE R. W. , BEDNARIK J. 
Published: April 2016

AbstractUntersucht werden l0 von Na‐borosilicat‐Glas abgeleitete Gläser, in denen SiO2 durch die Oxidkombination CeO2°C 3 Nbgos ersetzt ist (Zusammensetzung: 5‐20 mol‐% Na2O, 55‐70% B2O3, 20‐30% CeO2°C 3 Nb2O5).
Submarginal drumlin formation and late Holocene history of Fláajökull, southeast Iceland
Authors: Jónsson Sverrir Aðalsteinn , Benediktsson Ívar Örn , Ingólfsson Ólafur , Schomacker Anders , Bergsdóttir Helga Lucia , Jacobson William R. , Linderson Hans 
Published: April 2016

ABSTRACTFláajökull is a non-surging outlet glacier draining the south-eastern part of the Vatnajökull, southeast Iceland. Fláajökull was stationary or advanced slightly between 1966 and 1995 and formed a prominent end moraine. Glacial retreat since then has revealed a cluster of 15 drumlins. This study focuses on the morphology and sedimentology of the drumlins. They are 100–600 m long, 40–130 m wide, and have cores of glaciofluvial sediment or till. The drumlins are draped by ~1 m thick, massive subglacial traction till. The glacier forefield is characterized by a number of arcuate and saw-tooth, terminal and recessional moraine ridges, overridden moraines with fluted surfaces, and glaciofluvial outwash. Some of the drumlins extend towards the 1995 end moraine but terminate abruptly at the moraine and are not observed in front of it. This suggests that they were formed sub-marginally during the 1966–1995 terminal position. The sedimentary structure of the drumlins is best explained by the sticky spot model. Dating and dendrochronological analyses of birch logs found on the surface of one of the drumlins indicate that the valley was forested about 2100 calendar year BP, after which the glacier started to reform, possibly due to an abrupt change in climate.
An examination, translation and analysis of pencil inscriptions made under the bunks in the hut at Cape Adare by members of Borchgrevink's British Antarctic Expedition, 1898–1900
Authors: Mayer Jim 
Published: April 2016

ABSTRACT28 individual poems, notes, or drawings found and photographed under the bunks at Borchgrevink's hut at Cape Adare, Antarctica during two short visits on 1 February and 19 February 2015, are catalogued, translated and in many cases a source is identified. It has been possible to read and translate 24 of 28 markings. The relevance of a number of quotations, which express unhappiness with the leadership of the expedition and the emotional reaction of expedition members, are examined and placed in the context of the first over-wintering. Further targeted investigation, requiring specific permission, is suggested.
UNCERTAIN RIGHTS AGAINST DEFENSE
Authors: van der Vossen Bas 
Published: April 2016

Abstract:In this essay, I defend a theory of liability to defensive force. The theory contains two elements. The first is a dual Lockean-inspired condition. The second aims to make this first condition consistent with problems arising from uncertainty. Drawing on recent work by Michael Zimmerman, I argue that the rights-based condition should be made sensitive to the evidence available to defenders.
A Disaggregative View of Customary International Law-Making
Authors: VOYIAKIS EMMANUEL 
Published: April 2016

AbstractThis article argues that some familiar principles, like the protection of reasonable expectations or fair play, can justify the normative force and binding character of some types of customary international practices. We have no reason to think that any one of those principles can justify all customary practices that are typically taken to have such force. Accordingly, instead of proposing a unifying justification for all customary international law-making, I will suggest that the impact of past international practices on the normative situation of international agents is determined not by one master principle, but by a range of different normative principles, each applicable in different situations. If this is correct, i.e., if the principles that give customary practices their normative force vary depending on the kind of principle governing the practical problem that those practices are meant to respond to, both the critique and the defence of customary law-making must proceed on what I will call a ‘disaggregative’ basis.
Waltzing on the Vienna Consensus on Drug Control? Tensions in the International System for the Control of Drugs
Authors: BOISTER NEIL 
Published: April 2016

AbstractThis article examines the tensions within the international drug control system which are putting the until now consensual position in regard to the prohibition on drugs supply and use for anything other than medical and scientific use – the Vienna Consensus – under strain. The article examines a number of areas where policy stress is leading to controversy about potential violation of international drug control treaty obligations by states parties. Drawing a comparison with earlier periods of stress when drug control fell under the League of Nations, it suggests that what appears to be occurring is a shift in the Vienna consensus, and that the drug conventions are sufficiently flexible to permit resulting shifts in practice, although reform would be preferable.
Architecture as a Source for Local History in the Mongol Period: The Example of Warāmīn
Authors: BLAIR SHEILA 
Published: April 2016

AbstractThis article investigates the history of the Mongol period as seen from the provinces, looking not only through the historian's lens of written documents but also through the art historian's gaze on art and architecture. It focuses on the town of Warāmīn and its multiple shrines and shows how buildings and their furnishings, notable the extensive revetment in signed and dated lustre tiles, can be rich sources for writing history.
High Anger Expression is Associated with Reduced Cortisol Awakening Response and Health Complaints in Healthy Young Adults
Authors: Romero-Martínez Ángel , Moya-Albiol Luis 
Published: April 2016

AbstractThe extant evidence suggests a robust positive association between expression (anger expression-out) and suppression (anger expression-in) of anger and compromised health. Nevertheless, the underlying psychobiological mechanisms which explain these relationships are not well understood. This study examined whether anger expression would predict general health, cortisol awakening response (CAR) and evening cortisol levels in a community sample of 156 healthy young adults of both genders. Participants were distributed into two groups according to their anger expression scores: high and low anger expression (HAE and LAE, respectively). Findings indicated that those with HAE had worse self-reported health (p = .02) and higher CAR than the LAE group (p = .04). Moreover, high levels of anger expression-out (p < .01) and -in (p < .01, for all) predicted a worse self-reported health in both groups. On the other hand, high anger expression-out was associated with flattened CAR but only in the HAE group (p < .01). This study reinforces the need to develop effective strategies to provide mechanisms to regulate anger expression by promoting personal growth and positive skills that enhance individuals’ well-being and quality of life and, in turn, their own health.
Quantum hyperparallel algorithm for matrix multiplication
Authors: Zhang Xin-Ding , Zhang Xiao-Ming , Xue Zheng-Yuan 
Published: April 2016

AbstractHyperentangled states, entangled states with more than one degree of freedom, are considered as promising resource in quantum computation. Here we present a hyperparallel quantum algorithm for matrix multiplication with time complexity O(N2), which is better than the best known classical algorithm. In our scheme, an N dimensional vector is mapped to the state of a single source, which is separated to N paths. With the assistance of hyperentangled states, the inner product of two vectors can be calculated with a time complexity independent of dimension N. Our algorithm shows that hyperparallel quantum computation may provide a useful tool in quantum machine learning and “big data” analysis.
Characterization of key triacylglycerol biosynthesis processes in rhodococci
Authors: Amara Sawsan , Seghezzi Nicolas , Otani Hiroshi , Diaz-Salazar Carlos , Liu Jie , Eltis Lindsay D. 
Published: April 2016

AbstractOleaginous microorganisms have considerable potential for biofuel and commodity chemical production. Under nitrogen-limitation, Rhodococcus jostii RHA1 grown on benzoate, an analog of lignin depolymerization products, accumulated triacylglycerols (TAGs) to 55% of its dry weight during transition to stationary phase, with the predominant fatty acids being C16:0 and C17:0. Transcriptomic analyses of RHA1 grown under conditions of N-limitation and N-excess revealed 1,826 dysregulated genes. Genes whose transcripts were more abundant under N-limitation included those involved in ammonium assimilation, benzoate catabolism, fatty acid biosynthesis and the methylmalonyl-CoA pathway. Of the 16 atf genes potentially encoding diacylglycerol O-acyltransferases, atf8 transcripts were the most abundant during N-limitation (~50-fold more abundant than during N-excess). Consistent with Atf8 being a physiological determinant of TAG accumulation, a Δatf8 mutant accumulated 70% less TAG than wild-type RHA1 while atf8 overexpression increased TAG accumulation 20%. Genes encoding type-2 phosphatidic acid phosphatases were not significantly expressed. By contrast, three genes potentially encoding phosphatases of the haloacid dehalogenase superfamily and that cluster with, or are fused with other Kennedy pathway genes were dysregulated. Overall, these findings advance our understanding of TAG metabolism in mycolic acid-containing bacteria and provide a framework to engineer strains for increased TAG production.
Expression of guanylate cyclase-C, guanylin and uroguanylin is downregulated proportionally to the ulcerative colitis disease activity index
Authors: Lan Danfeng , Niu Junkun , Miao Jiarong , Dong Xiangqian , Wang Hong , Yang Gang , Wang Kunhua , Miao Yinglei 
Published: April 2016

AbstractThe transmembrane receptor guanylate cyclase-C (GC-C) signaling pathway has been implicated in several gastrointestinal disorders. Activation of GC-C via guanylin (Gn) and uroguanylin (Ugn) regulates intestinal fluid and electrolyte homeostasis. However, how it regulates the pathogenesis of inflammatory bowel disease (IBD) is still unclear. Here, we investigated the activation of GC-C signaling in ulcerative colitis (UC) of different clinical severities. A total of 60 UC patients and 20 normal controls were recruited. Evaluation of the UC disease activity index (DAI) was performed using a modified Mayo scoring system. The expression of GC-C, Gn and Ugn in the colonic mucosa was measured by quantitative real-time PCR and Western blot. We found that the UC patients had significantly lower expression of GC-C, Gn and Ugn than the controls. Furthermore, there were significant differences for GC-C, Gn and Ugn expression for the UC groups of Grade 1, 2 and 3 and their expression levels were reduced with increases in their DAI. Taken together, our results demonstrate that GC-C, Gn and Ugn are downregulated in UC and this downregulation is more significant with aggravation of the clinical condition. Therefore, the GC-C signaling pathway may be implicated in the progression of UC.
Modulation of Staphylococcus aureus spreading by water
Authors: Lin Mei-Hui , Ke Wan-Ju , Liu Chao-Chin , Yang Meng-Wei 
Published: April 2016

AbstractStaphylococcus aureus is known to spread rapidly and form giant colonies on the surface of soft agar and animal tissues by a process called colony spreading. So far, the mechanisms underlying spreading remain poorly understood. This study investigated the spreading phenomenon by culturing S. aureus and its mutant derivatives on Tryptic Soy Agarose (TSA) medium. We found that S. aureus extracts water from the medium and floats on water at 2.5 h after inoculation, which could be observed using phase contrast microscopy. The floating of the bacteria on water could be verified by confocal microscopy using an S. aureus strain that constitutively expresses green fluorescence protein. This study also found that as the density of bacterial colony increases, a quorum sensing response is triggered, resulting in the synthesis of the biosurfactants, phenolic-soluble modulins (PSMs), which weakens water surface tension, causing water to flood the medium surface to allow the bacteria to spread rapidly. This study reveals a mechanism that explains how an organism lacking a flagellar motor is capable of spreading rapidly on a medium surface, which is important to the understanding of how S. aureus spreads in human tissues to cause infections.
Gate-Tunable Spin Transport and Giant Electroresistance in Ferromagnetic Graphene Vertical Heterostructures
Authors: Myoung Nojoon , Park Hee Chul , Lee Seung Joo 
Published: April 2016

AbstractControlling tunneling properties through graphene vertical heterostructures provides advantages in achieving large conductance modulation which has been known as limitation in lateral graphene device structures. Despite of intensive research on graphene vertical heterosturctures for recent years, the potential of spintronics based on graphene vertical heterostructures remains relatively unexplored. Here, we present an analytical device model for graphene-based spintronics by using ferromagnetic graphene in vertical heterostructures. We consider a normal or ferroelectric insulator as a tunneling layer. The device concept yields a way of controlling spin transport through the vertical heterostructures, resulting in gate-tunable spin-switching phenomena. Also, we revealed that a ‘giant’ resistance emerges through a ferroelectric insulating layer owing to the anti-parallel configuration of ferromagnetic graphene layers by means of electric fields via gate and bias voltages. Our findings discover the prospect of manipulating the spin transport properties in vertical heterostructures without use of magnetic fields.
Contribution of dermal-derived mesenchymal cells during liver repair in two different experimental models
Authors: Tan Li , Dai Tingyu , Liu Dengqun , Chen Zelin , Wu Liao , Gao Li , Wang Yu , Shi Chunmeng 
Published: April 2016

AbstractProgressive liver disease is a major health issue for which no effective treatment is available, leading to cirrhosis and orthotopic liver transplantation. However, the lack of availability of donor organs and other adverse factors including rejection limit its extensive clinical application. Cell-based therapy using mesenchymal stem/stromal cells (MSCs) may represent an attractive therapeutic option. Dermal-derived mesenchymal cells (DMCs) are attractive as one of the abundant sources from which to isolate mesenchymal cells for therapeutic applications and can be easily accessed with minimal harm to the donor. In this study, we used two different animal models to investigate potential therapeutic effect of DMCs transplantation in liver injury. We found that DMCs administration alleviated liver fibrosis and restored the liver function in fibrotic mice induced by CCl4. Furthermore, in an acute irradiation induced damage model, a unique population of DMCs could engraft into the liver tissue for a long period, exhibiting the phenotype of both mesenchymal cells and macrophage cells and improve the survival of mice exposed to 8 Gy lethally total-body irradiation. These discoveries provide important evidence that DMCs therapy has a beneficial effect on liver injury and provide new insight into liver injury therapy depending on the alternative cells.