bluuebunny/crossref_metadata_2025_split huggingface dataset:
INVESTMENT ATTRACTIVENESS OF THE REGIONS IN CONDITIONS OF MODERN CHALLENGES
Authors: Шамрай И.Н. , Давиденко Л.М. , Нитяго И.В. 
Published: September 2024

В данной работе проведен анализ инвестиционной привлекательности на уровне регионов как фактора интеграции бизнес-структур, научно-технологических, индустриальных центров. С целью оценки и систематизации критериев инвестиционной привлекательности потенциальных партнеров для хозяйственных субъектов, государственных структур, научно-образовательных комплексов приводится классификация индикаторов инновационного устойчивого роста. Посредством метода квантификации и основополагающих подходов сравнительного метода продемонстрированы результаты взаимовыгодного межрегионального сотрудничества соседних регионов России и Казахстана. Делается вывод о том, что развитость институциональной среды, интегрированных промышленных комплексов, инжиниринговых и научно-технологических центров, сбытовых и посреднических сетей становится фундаментом для высокотехнологичной активности всех элементов региональных экосистем.
This paper analyzes the investment attractiveness at the regional level as a factor in the integration of business structures and scientific and technological centers. In order to assess and systematize the criteria for investment attractiveness of potential partners for business entities, government agencies, research centers, educational complexes, the authors develop a classification of indicators of innovative sustainable growth. Using the quantification method and the fundamental approaches of the comparative method, the authors provide the results of mutually beneficial interregional cooperation between neighboring regions of Russia and Kazakhstan. It is concluded that the development of the institutional environment, integrated industrial complexes, engineering and scientific and technological centers, marketing networks becomes the foundation for a high-tech level of activity of all elements of regional ecosystems.
A REPERCUSSÃO DA CIRURGIA DE READEQUAÇÃO SEXUAL EM PESSOAS TRANSGÊNERO
Authors: Silva Maria Eduarda Monteiro Pereira da , Pereira Kátia Monteiro , Nascimento Thayza Sandôra do , Evangelista Nabilla Araujo , Barboza Érica de Almeida 
Published: September 2024

Esse artigo buscou analisar as repercussões existentes da cirurgia de readequação sexual e seus desdobramentos. A cirurgia de readequação sexual é considerada o tratamento mais eficiente para a disforia de gênero, sobretudo as cirurgias genitais. Diversos estágios estão envolvidos em um pré-operatório de uma cirurgia para readequação de gênero, e essa preparação pode levar até 12 meses para ser concluída. No que diz respeito à cirurgia de vaginoplastia, existem duas técnicas utilizadas: a de inversão peniana, que é a mais realizada devido à possibilidade de maior conservação da inervação e menor taxa de complicações, e a vaginoplastia com abordagem do retossigmóide, usada em casos específicos. Para a construção da genitália masculina, existe a possibilidade da escolha entre a metoidioplastia, que consiste na construção do pênis através do clitóris, faloplastia, realizada através de retalhos de pele, e a implantação de uma prótese peniana. Evidencia-se efeito benéfico na qualidade de vida após a cirurgia de readequação sexual em pessoas transgênero, englobando questões de saúde sexual e mental. Contudo, existe uma escassez de evidências atuais sobre o procedimento e de questionários de satisfação pós-cirurgia, algo que prejudica o abrangente cuidado com esses pacientes.
Revisiting the subtyping of bowel-based disorders using unsupervised machine learning
Authors: Dowrick Jarrah 
Published: September 2024

The Rome IV criteria, a widely used symptom-based diagnostic tool for disorders of gut-brain interaction (DGBI), have enabled clinicians to provide diagnoses for patients whose gastrointestinal (GI) symptoms lack organic explanations. However, challenges remain in identifying robust diagnostic biomarkers, predicting treatment outcomes, and ensuring diagnostic stability. Unsupervised machine learning can be used to step beyond existing clinical definitions to uncover intrinsic patient subtypes possibly unburdened by these limitations. In this talk, Jarrah will provide an overview of bowel-based DGBI subtyping, present the findings from his recent application of unsupervised machine learning to revisit this problem, and introduce his next steps in improving DGBI diagnosis and treatment strategies.
The Impact of Gold Mining on Community Income in Poboya Village, Mantikulore District, Palu City
Authors: Selawati S. , Rafika Ika 
Published: September 2024

The purpose of this study was to determine the impact of gold mining on community income in Poboya Village, Mantikulore sub-district, Palu City. This research was conducted using qualitative and quantitative research methods. The data sources used in this research are primary data and secondary data with data collection techniques, namely observation, interviews and documentation, the data obtained is then analyzed into a conclusion from the research process. The findings of the study found that the Impact of Gold Mining on Community Income in Poboya Village, Mantikulore District, Palu City had a positive impact and a negative impact on mining. The positive impact of gold mining can improve the economy of miners, while the negative impact poses a greater danger, especially the impact on the environment.
Modelo organizacional para evaluar la calidad de la administración en las organizaciones deportivas
Authors: Aguilera Rivera Alberto Rafael 
Published: September 2024

La globalización y los avances tecnológicos han transformado el alcance de las entidades deportivas. Hoy se requiere que el análisis de este tipo de organizaciones se aborde desde teorías y modelos caracterizados por una visión moderna; su estudio debe realizarse a partir de conocimientos integrales que inicien con el análisis del tipo y la calidad de la administración con la que cuenta para operar y gestionar de manera adecuada y profesional. Esto implica que se analice todo lo que requiere la gestión y operación organizacional. El presente artículo tiene el objetivo de exponer un modelo organizacional que evalúe la calidad de la administración en las organizaciones deportivas, dado que deben operar eficientemente en ambientes muy competidos, no sólo en el espacio deportivo sino en el económico, no importando su carácter público, privado o social. Para tal propósito se toma como referencia la teoría organizacional al respecto de la evaluación de una organización y se propone un modelo propio adecuado con sus respectivas adaptaciones, adiciones y mejoras al ámbito deportivo, para este tipo de entidades, concluyendo en el aporte que se tiene como instrumento que sirve para determinar de manera racional, coherente y profesional la calidad de administración en una organización que tiene en el deporte su razón de ser y existir.
Peran Guru dalam Mengembangkan Karakter Kerja di Lingkungan Sekolah
Authors: Rizkiyana Muhammad Fadlan , Suhardi Imelda Syintha Dewy , Dewi Ratna Sari 
Published: September 2024

Penelitian ini membahas peran guru dalam mengembangkan karakter kerja keras di lingkungan sekolah. dan bertujuan untuk mengetahui bagaimana guru dapat meningkatkan motivasi siswa dan meningkatkan kualitas pendidikan melalui pengembangan karakter kerja keras. Penelitian ini menggunakan metode metode kualiitatif dengan pendekatan studi kasus. Teknik pengumpulan data dilakukan melalui observasi, partisipan, wawancara mendalam, dan analisis dokumen. Hasil penelitian menunjukkan bahwa guru memiliki peran penting dalam mengembangkan karakter kerja keras siswa melalui berbagai strategi; Guru dapat menanamkan nilai-nilai kerja keras kepada siswa melalui contoh dan keteladanan, serta melalui pembelajaran di kelas dan kegiatan ekstrakurikuler, Guru dapat memberikan motivasi dan dorongan kepada siswa untuk bekerja keras dengan menciptakan lingkungan belajar yang positif dan kondusif, serta dengan memberikan penghargaan atas prestasi siswa.
اثر التحرش اللفظي على العامل النفسي لدى طالبات كلية علوم الرياضة في الجامعة الاردنية
Authors: انس محمد خير رشيد كايد  
Published: September 2024

هدفت الدراسة التعرف الى اثر التحرش اللفظي على العامل النفسي لدى طالبات كلية علوم الرياضة في الجامعة الاردنية ، و استخدم الباحث المنهج الوصفي لما يتناسب و طبيعة هذه الدراسة ، وتكون مجتمع الدراسة من طالبات كلية علوم الرياضة في الجامعة الاردنية مرحلة البكالوريوس والدراسات العليا وعددهم (754) طالبة ، وتم اختيار مجموعة عشوائية مكونة من ن = (92) طالبة وتم توزيع الاستبيان الذي قام بإعداده الباحث عليهن ، ولمعالجة بيانات الاستبيان استخدم الباحث برنامج الحزم الاحصائية للعلوم الاجتماعية spss للحصول على المتوسطات الحسابية و حساب معامل الثبات الفا كرونباخ والانحراف المعياري للفقرات و الرتب و التصنيف و الاهمية النسبية ، و اظهرت اهم النتائج ان 25% من عينة البحث قد تعرضو للتحرش اللفظي و ان معايير الحكم على عبارات الاستبيان تراوحت بين (2.30-4.26) وهي بين المتوسط والمرتفع من حيث تأثر العامل النفسي من التحرش اللفظي الواقع على الطالبات ولم تظهر النتائج اي فروق ذات دلالة احصائية بين طالبات الدراسات العليا و البكالوريوس كمتغير للمؤهل العلمي .و يوصي الباحث بعمل ورشات اجتماعية للتعريف و التوعية بمخاطر و اثار التحرش اللفظي وتأثيره على العامل النفسي في المجتمع المحلي و الاكاديمي ، ووضع و تفعيل قوانين لردع و منع انتشار هذه الظاهرة و عدم التهاون في تطبيقها ، وعمل دراسات حول اشكال التحرش اللفظي و غير اللفظي و اقتراح حلول للحد منه .
Qual a relação do personagem tédio de Divertida Mente 2 com a sociedade das telas e à desinformação?
Authors: Teixeira Pollyana Ferrari 
Published: September 2024

Crianças e adolescentes brasileiros estão passando mais tempo com celulares do que na escola ou num lazer fora das telas. A presença deles na rede está permeada por riscos, incluindo exposição a conteúdo inadequado, ameaças à privacidade, cyberbullying e manipulação por parte de plataformas digitais. Como promover o uso da tecnologia de modo a aproveitar todo seu potencial, ao mesmo tempo em que cuidamos do desenvolvimento neurológico? O objetivo deste artigo é mapear as evidências sobre o adoecimento psicológico em crianças e adolescentes causado pelo uso excessivo de telas em meio à indústria da desinformação. Trata-se de uma revisão integrativa da literatura. Para tanto, usaremos dois exemplos: a animação Divertida Mente 2, dos estúdios Disney/Pixar, que se tornou a maior bilheteria de 2024, após encerrar o final de semana de estreia com valor arrecadado de US$ 724,4 milhões (aproximadamente R$ 3,9 bilhões), e o uso de crianças e adolescentes brasileiros como influenciadores para vender o jogo de azar conhecido como “jogo do tigrinho”. Além disso, a pesquisa traz iniciativas de pais brasileiros que visam a desconexão dos filhos até 16 anos; até 8 anos em Londres e projetos com idades variadas nos Estados Unidos – todos inspirados pelas pesquisas do psicólogo social norte-americano Jonathan Haidt, autor de “A geração ansiosa”.
Determination of methotrexate using carbon paste electrode modified with ionic liquid/Ni-Co layered double hydroxide nanosheets as a voltammetric sensor
Authors: Mohammadzadeh Jahani Peyman , Garkani Nejad Fariba , Zaimbashi Reza , Aflatoonian Mohammad Reza , Tajik Somayeh , Beitollahi Hadi 
Published: September 2024

Background and purpose: Methotrexate (MTX) is a widely used anti-cancer drug, but its overuse can lead to significant side effects. Therefore, it is very vital to design simple and sensitive analytical methods for its determi­na­tion. Experimental approach: In this work, an electrochemical sensor was prepared based on an ionic liquid (IL)/Ni-Co layered double hydroxide nanosheets (Ni-Co-LDH)-modified carbon paste electrode IL/Ni-Co-LDH/CPE. Cyclic voltammetry, differential pulse voltammetry, and chronoamperometry methods were applied to evaluate the performance of the designed sensor for MTX determination. Key results: The IL/Ni-Co-LDH/CPE sensor exhibits a linear relationship between the peak current of the differential pulse voltammetry and MTX concentrations in the linear dynamic range of 0.02 to 140.0 µM, with a detection limit of 0.006 µM. The IL/Ni-Co-LDH/CPE sensor exhibited relative standard deviation values between 1.7 to 3.7 % for recovery tests on real samples, indicating the precision of the method. Conclusion: The designed sensor with cost-effective and good performance could be valuable for therapeutic drug monitoring and clinical diagnostics.
Effect of focus group opinions on final film making product: Sociological and marketing aspects
Authors: Oktrova Mirela 
Published: September 2024

Introduction: Focus groups are widely used today for researching film product concepts, testing, advertising, and viewer satisfaction. Objective: to reveal the ideas and concepts of focus groups in the film industry to form research hypotheses and understand the perception and attitude of group interview participants to the phenomena and problems of film production. Methods: Methodology used in this study was a survey with 354 respondents divided into 52 groups to cover various demographic characteristics (age, social status, ethnicity). Results: The analysis of the study showed that group focus interviews can be used to collect additional data after quantitative surveys and help to interpret the results more fully. The analysis described the use of focus groups as a demand tool based on personal experience, paying particular attention to the purpose, stage, and content. The results showed that group discussions often lead to many ideas and inspirations that can be gathered on a topic in a very short time, efficiently and quickly, and respondents can compare and analyse their personal experiences, which is a valuable resource. Conclusions: Research relevance is highlighted by the effectiveness of focus group discussions in helping businesses in the film industry understand consumer insights better than general surveys
SARCOPENIA IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Authors: Завьялова Анна Никитична , Фирсова Людмила Алексеевна , Новикова Валерия Павловна , Яковлева Милена Николаевна , Прокопьева Наталья Эдуардовна 
Published: September 2024

В последнее время снижение мышечной массы и функции при саркопении часто обсуждаются врачами и учеными разных направлений. Диагностика саркопении в структуре хронических заболеваний, в том числе у больных хронической болезнью почек, является важнейшим аспектом при выборе тактики ведения пациента. Доказано, что наличие у больного саркопении имеет прямую корреляционную связь с частотой летальных и других неблагоприятных исходов, а у детей нарушает физиологическое течение роста и развития. К сожалению, на данный момент отсутствуют общепринятые подходы к диагностике и лечению саркопении у пациентов как взрослого, так и детского возраста. В данной статье представлен литературный обзор, в котором собраны современные взгляды отечественных и зарубежных ученых о саркопении у пациентов с хронической болезнью почек.
Sarcopenia as a decrease in muscle mass, and more importantly, its function is widely discussed by physicians and scientists of different specialties. Diagnosis of sarcopenia in structure of chronic diseases, including in patients with chronic kidney disease, is the most important aspect in the choice of management of a patient. It has been proved that the presence of sarcopenia has a direct correlation with the frequency of lethal and other unfavorable outcomes, and in children it disturbs the physiological course of growth. Unfortunately, at the moment there are no generally accepted approaches to the diagnosis and treatment of sarcopenia in both adult and children. This article presents a review of foreign and domestic studies on sarcopenia.
THE PLACE OF GLUCAGON-LIKE PEPTIDE-1 RECEPTOR AGONISTS IN THE DRUG THERAPY OF OBESITY AT THE PRESENT STAGE
Authors: Шаповалова Анна Борисовна , Смирнов Виктор Владимирович , Титова Дарья Олеговна 
Published: September 2024

В статье, представляющей собой обзор современных литературных данных и результатов клинических исследований, рассмотрены наиболее актуальные подходы к медикаментозному лечению ожирения с применением агонистов рецепторов глюкагонподобного рецептора-1 (аГПП-1). Высокая частота распространенности ожирения требует разработки новых стратегий, что, в свою очередь, ориентирует практического врача и исследователей на поиск новых эффективных и безопасных препаратов. В статье подробно рассмотрены особенности распространенности применения аГПП-1 на сегодня в мире, их эффективность при снижении веса, доказанные ограничения применения аГПП-1, побочные эффекты и безопасность при длительном использовании, место данной группы при хирургическом лечении ожирения и некоторые экономические аспекты. Применение аГПП-1 на современном этапе является очень важным шагом к развитию патогенетического подхода к лечению. Однако эффективность и безопасность представителей класса необходимо учитывать при выборе лечебной тактики при ожирении в зависимости от наличия сахарного диабета и сопутствующих заболеваний. Необходимы дальнейшие исследования, на основании результатов которых будут разработаны современные клинические рекомендации.
The review of current literature data and clinical research results presents the most relevant approaches to the drug treatment of obesity using glucagon-like receptor-1 agonists (aGPP-1). The high prevalence of obesity requires the development of new strategies, which, in turn, orients the practitioner and researchers to search for new effective and safe drugs. The article discusses in detail the features of the prevalence of the use of aGPP-1 in the world today, their effectiveness in weight loss, proven limitations of the use of aGPP-1, side effects and safety with prolonged use, the place of this group in the surgical treatment of obesity and some economic aspects. The use of aGPP-1 at the present stage of obesity treatment is a very important step towards the development of a pathogenetic approach to treatment. However, the effectiveness and safety of various representatives of the class must be taken into account when choosing therapeutic tactics in obese patients, depending on the presence of diabetes mellitus and concomitant diseases, as well as complex therapy. Further studies are needed, based on the results of which modern clinical recommendations will be developed.
EOSINOPHILIC NEUROTOXIN AND ITS CLINICAL SIGNIFICANCE IN PEDIATRICS
Authors: Листопадова Анастасия Павловна , Замятина Юлия Евгеньевна , Михайлова Ксения Алексеевна 
Published: September 2024

В статье описывается, какое значение имеет эозинофильный нейротоксин при диагностике различных заболеваний у детей. Данный обзор представляет собой обобщение источников и экспертного заключения автора. Эозинофильный нейротоксин — неинвазивный биомаркер, предназначенный для оценки эозинофильной активации. Определение уровня&nbsp; эозинофильного нейротоксина является хорошим инструментом для персонализированного терапевтического подхода в лечении воспалительных и аллергических заболеваний. Он имеет действительную значимость определения у детей при таких заболеваниях, как бронхиальная астма, атопический дерматит, эозинофильный эзофагит, пищевая аллергия и воспалительные заболевания кишечника.
The article describes the importance of eosinophilic neurotoxin in the diagnosis of various allergic diseases and inflammatory bowel diseases in children. This review is a summary of the author’s sources and expert opinion. Eosinophilic neurotoxin is a non-invasive biomarker designed to assess eosinophilic activation. Determining the level of eosinophilic neurotoxin is a goodtool for a personalized therapeutic approach in the treatment of inflammatory and allergic diseases. It has real significance in determining children with diseases such as bronchial asthma, atopic dermatitis, eosinophilic esophagitis, food allergies and inflammatory bowel diseases.
Neuroticism, coping styles and psychological distress among frontliners during COVID-19 pandemic in Kelantan, Malaysia
Authors: Chidambar Subramanian Barath , Shafini Bakar Raishan , Che Rahimi Aisyah , Mohd Yasin Mohd Azhar 
Published: September 2024

The study aimed to determine the prevalence of psychological distress and explore the roles of neuroticism traits and coping styles among frontliners during the COVID-19 pandemic in Malaysia. A total of 336 frontline healthcare workers from three COVID-19 hospitals in Malaysia participated in the online survey. The measurements, including sociodemographic characteristics, presence of psychological distress, neuroticism traits, and coping styles, were assessed using the sociodemographic proforma, General Health Questionnaire (GHQ-12), Big Five Inventory, and Brief COPE scales.Descriptive analysis with SPSS-26 were performed to determine the socio-demographic attributes of the participants, level of trait neuroticism, coping styles and psychological distress. Multiple logistic regression analysis was carried out to determine the factors significantly associated with psychological distress.Results showed that out of 336 frontliners, 22.9% reported psychological distress. Higher trait neuroticism was significantly associated with an increased risk of psychological distress (p < 0.05), while religious coping was significantly associated with a decreased risk of psychological distress (p < 0.05). Other sociodemographic factors, such as age, gender, and years of experience, did not show significant associations with psychological distress.The high prevalence of psychological distress among frontliners highlights the importance of addressing their mental health needs during pandemics. Interventions aimed at enhancing psychological well-being should consider targeting neuroticism traits and promoting adaptive coping strategies, such as religious coping.
Uji Aktivitas Antihipertensi Seduhan Rambut Jagung (Zea mays L.) Terhadap Mencit Jantan Galur Swiss Webster
Authors: Septiyan Taufik , Dewi Lisna , Saepudin Syumillah , Rahayu Iseu 
Published: September 2024

Hipertensi atau tekanan darah tinggi adalah suatu keadaan kronis dengan meningkatnya tekanan darah pada dinding pembuluh darah arteri. Hipertensi ditandai dengan terjadinya peningkatan tekanan darah yang tidak normal dan menetap pada beberapa kali pengukuran tekanan darah yang disebabkan oleh satu atau lebih faktor risiko yang tidak bekerja dengan baik untuk mempertahankan tekanan darah normal. Salah satu tumbuhan yang dimanfaatkan dalam pengobatan tradisional adalah rambut jagung (Zea Mays L.) umumnya digunakan oleh masyarakat sebagai obat herbal dengan cara diseduh. Bagian tanaman ini mengandung banyak manfaat karena mengandung senyawa metabolit seperti flavonoid yang berperan sebagai antioksidan. Uji aktivitas antihipertensi dilakukan dengan induksi NaCl 2% dengan cara oral serta mengukur tekanan darah menggunakan metode non-invasive Blood Pressure dengan alat Mice rat blood pressure IT science terhadap mencit. Respon antihipertensi ditandai dengan meningkatnya tekanan darah hewan uji. Seduhan rambut jagung dengan dosis 2, 4 dan 6 gram memiliki efek antihipertensi terhadap mencit jantan galur Swiss webster. Seduhan rambut jagung yang paling berpengaruh terdapat pada seduhan rambut jagung dengan dosis 4 gram (dosis 2) karena dosis tersebut memberikan pengaruh yang paling mendekati obat amlodipin. Seduhan rambut jagung memiliki kadar flavonoid sebesar 5,366 mg/L dan kadar alkaloid yang didapatkan sebesar 1,176 mg/L.

Kata Kunci: Hipertensi; Rambut jagung; NaCl; Mencit; Non-invasive Blood Pressure.