bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular Risk Factors in Adolescents With Celiac Disease
Authors: Assa Amit , Frenkel‐Nir Yael , Tzur Dorit , Katz Lior H. , Shamir Raanan 
Published: November 2016

ABSTRACTBackground:Recent data have shown that adults with celiac disease (CD) may have a higher prevalence of risk factors for cardiovascular disease (CVD) compared with the general population. Thus, we aimed to investigate the association of CD with CVD risk factors at late adolescence in a cross‐sectional population‐based study.Methods:A total of 2,001,353 Jewish Israeli adolescents who underwent a general health examination at median age of 17.1 years from 1988 to 2015 were included. Covariate data included demographic measures, blood pressure (BP), resting heart rate, and risk factors associated with CVD.Results:Overall, 10,566 cases of CD were identified (0.53%). Multivariate analysis showed that mean diastolic BP was significantly lower in subjects with CD (men: 72.0±8.7 vs 70.4 ± 8.5, P < 0.0001; women: 70.0 ± 8.3 vs 69.0 ± 8.2, P < 0.0001), whereas systolic BP did not differ between groups. Resting heart rate was higher in CD cases (an absolute difference of 0.4 beats per minute, P < 0.0001). The proportions of overweight and obese subjects were significantly lower in CD cases. Noninsulin‐dependent diabetes mellitus (relative risk [RR], 4.1; 95% confidence interval [CI] 2.8–5.7), hypercoagulability (RR, 2.6; 95% CI 1.5–4.5), and hyperlipidemia (RR, 1.9; 95% CI 1.2–3) were significantly more common in subjects with CD.Conclusions:At the age of 17 years, the prevalence of risk factors for CVD is higher in subjects with CD compared with the general population. There is, however, neither increase in BP nor increase in overweight and obesity rates.
Classifying Patients’ Complaints for Regulatory Purposes: A Pilot Study
Authors: Bouwman Renée , Bomhoff Manja , Robben Paul , Friele Roland 
Published: November 2016

Objectives
It is assumed that classifying and aggregated reporting of patients’ complaints by regulators helps to identify problem areas, to respond better to patients and increase public accountability. This pilot study addresses what a classification of complaints in a regulatory setting contributes to the various goals.

Methods
A taxonomy with a clinical, management, and relationship domain was used to systematically analyze 364 patients’ complaints received by the Dutch regulator.

Results
Most complaints were about hospital care, mental health care, and elder care. About certain sectors such as emergency care, little numbers of complaints were received. The largest proportion of complaints concerned the clinical domain (51%), followed by the management domain (47%) and the relationship domain (42%).
Clinical domain complaints were more prevalent in elder care (65%) than in hospital care (56%) and mental health care (41%). In complaints about mental health care, the relationship domain was the most important (65%). The management domain was most prevalent in elder care (49%) compared with the other sectors.

Conclusions
Problem areas within different health-care sectors could be identified by classifying the complaints. It provided insight in the regulator’s own practices, which are aimed at public accountability. However, there are several limitations. Aggregated analyses were not possible in sectors with low numbers of complaints. Furthermore, the information remains rather superficial, and a standardized detailed system of reporting among agencies is needed. To assess which complaints need regulatory action, an in-depth analysis, using standardized methodology and criteria, of specific complaints is needed. Improving responses to patients requires more than merely aggregated reporting of complaints.
foxQ2 evolved a key role in anterior head and central brain patterning in protostomes
Authors: Kitzmann Peter , Weibkopf Matthias , Schacht Magdalena Ines , Bucher Gregor 
Published: November 2016

AbstractAnterior patterning of animals is based on a set of highly conserved transcription factors but the interactions within the protostome anterior gene regulatory network (aGRN) remain enigmatic. Here, we identify thefoxQ2ortholog of the red flour beetleTribolium castaneumas novel upstream component of the insect aGRN. It is required for the development of the labrum and higher order brain structures, namely the central complex and the mushroom bodies. We revealTc-foxQ2interactions by RNAi and heat shock-mediated misexpression. Surprisingly,Tc-foxQ2andTc-six3mutually activate each other forming a novel regulatory module at the top of the insect aGRN. Comparisons of our results with those of sea urchins and cnidarians suggest thatfoxQ2has acquired functions in head and brain patterning during protostome evolution. Our findings expand the knowledge onfoxQ2gene function to include essential roles in epidermal development and central brain patterning.Author summaryThe development of the anterior most part of any animal embryo – for instance the brain of vertebrates and the head of insects – depends on a very similar set of genes present in all animals. This is true for the two major lineages of bilaterian animals, the deuterostomes (including sea urchin and humans) and protostomes (including annelids and insects) and the cnidarians (e.g. the sea anemone), which are representatives of more ancient animals. However, the interaction of these genes has been studied in deuterostomes and cnidarians but not in protostomes. Here, we present the first study the function of the genefoxQ2in protostomes. We found that the gene acts at the top level of the genetic network and when its function is knocked down, the labrum (a part of the head) and higher order brain centers do not develop. This is in contrast to the other animal groups wherefoxQ2appears to play a less central role. We conclude thatfoxQ2has acquired additional functions in the course of evolution of protostomes.
Mindcontrol: A Web Application for Brain Segmentation Quality Control
Authors: Keshavan Anisha , Datta Esha , McDonough Ian , Madan Christopher R. , Jordan Kesshi , Henry Roland G. 
Published: November 2016

AbstractTissue classification plays a crucial role in the investigation of normal neural development, brain-behavior relationships, and the disease mechanisms of many psychiatric and neurological illnesses. Ensuring the accuracy of tissue classification is important for quality research and, in particular, the translation of imaging biomarkers to clinical practice. Assessment with the human eye is vital to correct various errors inherent to all currently available segmentation algorithms. Manual quality assurance becomes methodologically difficult at a large scale - a problem of increasing importance as the number of data sets is on the rise. To make this process more efficient, we have developed Mindcontrol, an open-source web application for the collaborative quality control of neuroimaging processing outputs. The Mindcontrol platform consists of a dashboard to organize data, descriptive visualizations to explore the data, an imaging viewer, and an in-browser annotation and editing toolbox for data curation and quality control. Mindcontrol is flexible and can be configured for the outputs of any software package in any data organization structure. Example configurations for three large, open-source datasets are presented: the 1000 Functional Connectomes Project (FCP), the Consortium for Reliability and Reproducibility (CoRR), and the Autism Brain Imaging Data Exchange (ABIDE) Collection. These demo applications link descriptive quality control metrics, regional brain volumes, and thickness scalars to a 3D imaging viewer and editing module, resulting in an easy-to-implement quality control protocol that can be scaled for any size and complexity of study.
Multimodal representations of person identity individuated with fMRI
Authors: Anzellotti Stefano , Caramazza Alfonso 
Published: November 2016

AbtractRecognizing the identity of a person is fundamental to guide social interactions. We can recognize the identity of a person looking at her face, but also listening to her voice. An important question concerns how visual and auditory information come together, enabling us to recognize identity independently of the modality of the stimulus. This study reports converging evidence across univariate contrasts and multivariate classification showing that the posterior superior temporal sulcus (pSTS), previously known to encode polymodal visual and auditory representations, encodes information about person identity with invariance within and across modality. In particular, pSTS shows selectivity for faces, selectivity for voices, classification of face identity across image transformations within the visual modality, and classification of person identity across modality.
Benchmarking mutual fund alpha
Authors: Bu Qiang 
Published: November 2016

Purpose
The standard market models assume that all investors are rational with the same level of risk aversion, whereas investors in the real world are neither rational nor homogeneous. This contrast makes these models inappropriate for evaluating manager skill. The purpose of this paper is to attempt to bridge the gap between model assumption and fund investment practice.

Design/methodology/approach
This study proposes a series of modified models using the excess return of peer funds to estimate fund alpha. In these models, the market excess return in the standard market models is replaced with the average excess return of bootstrapped funds. In addition, the author examines the reasons for the difference between the modified models and the standard models.

Findings
The modified models better explain the variation of fund returns, and they exhibit that a considerably higher percentage of funds can earn positive alpha, thus the skill of fund managers is underestimated based on the standard market models.

Originality/value
The proposed models provide a more reliable method for investors to identify skilled fund managers, and they can also serve as an objective benchmark in evaluating fund performance and in designing manager compensation packages.
Supplier selection in small- and medium-sized firms
Authors: Su Jin , Gargeya Vidyaranya B. 
Published: November 2016

Purpose
The purpose of this paper is to empirically examine supplier selection among small- and medium-sized firms in the US textile and apparel industry. For small- and medium-sized firms, one powerful method of improving the firm’s competitiveness in the dynamic business environment is through strategic approach of supplier selection, which emphasizes supplier’s contributions to the total product and to overall customer satisfaction.

Design/methodology/approach
Empirical survey-based research methodology was implemented and data were collected from small and medium firms in textile and apparel business in North Carolina, South Carolina, Georgia, California, and New York which are the major areas of the US textile and apparel industry.

Findings
This study demonstrates the supplier selection practices of the small- and medium-sized firms in the US textile and apparel industry and their perceptions of supply market and supplier evaluation systems. Results indicate that supplier selection criteria impact firm performance in different ways. Small- and medium-sized firms carry out supplier selection based on product quality, supplier responsiveness, and strategic consideration which positively impact overall customer service level and overall customer satisfaction.

Originality/value
This paper focuses on supply chain management practices, specifically the supplier selection issue in small- and medium-sized firms in the textile and apparel industry.
Young consumers’ brand communications literacy in a social networking site context
Authors: Lawlor Margaret-Anne , Dunne Áine , Rowley Jennifer 
Published: November 2016

Purpose
While substantial scholarly attention has been given to children’s understanding of advertising in the context of traditional advertising channels, there is a gap in the literature with regard to children’s commercial awareness in the context of online social networking sites. This paper aims to seek to explore the nature and extent of advertising literacy among young consumers in the context of their use of social networking sites, namely, Facebook and Bebo.

Design/methodology/approach
A three-stage study was conducted with 12 to 14-year-old girls, using focus group discussions, participant observation and in-depth interviews.

Findings
The study illustrates that the increasingly blurred line between online advertising and other forms of online brand-related content is militating against the development of advertising and marketing literacy in young consumers. A key issue which is discussed is the extent to which the traditional conceptualisation of advertising literacy is “fit for purpose” in an online context.

Originality/value
The authors propose an alternative to the advertising literacy concept, namely, the Online Brand Communications literacy framework. This framework recognises the convergence of traditional online advertising and other forms of online brand content and also acknowledges that the messaging around a brand may originate from the brand owner in a variety of overt and covert forms. Equally, online consumers may also act as brand promoters when they engage in brand-related word-of-mouth.
The socio-materiality of parental style
Authors: Bettany Shona M. , Kerrane Ben 
Published: November 2016

PurposeThis study aims to offer understanding of the parent – child relationship by examining, through a socio-material lens, how one aspect of the new child surveillance technology market, child GPS trackers (CGT), are rejected or adopted by families, highlighting implications for child welfare, privacy and children’s rights policy.Design/methodology/approachThe authors gathered netnographic data from a range of online sources (parenting forums, online product reviews, discussion boards) that captured parental views towards the use of CGT and stories of the technology in use and theorize the data through application of a novel combination of neutralisation and affordance theory.FindingsThe research reveals how critics of CGT highlight the negative affordances of such product use (highlighting the negative agency of the technology). Parental adopters of CGT, in turn, attempt to rationalize their use of the technology as a mediator in the parent – child relation through utilisation of a range of neutralisation mechanisms which re-afford positive product agency. Implications for child welfare and policy are discussed in the light of those findings.Originality/valueThe paper presents an empirical, qualitative understanding of parents negotiating the emergence of a controversial new child-related technology – CGT – and its impact upon debates in the field of parenting and childhood; develops the theory of parental style towards parental affordances, using a socio-material theoretical lens to augment existing sociological approaches; and contributes to the debates surrounding child welfare, ethics, privacy and human rights in the context of child surveillance GPS technologies.
The role of C-OAR-SE in marketing measurement
Authors: Bergkvist Lars 
Published: November 2016

Purpose
This paper aims to offer a comment on Rossiter’s C-OAR-SE article and suggests future developments for the practical application of C-OAR-SE that would promote its usage and acceptance among marketing scholars.

Design/methodology/approach
This is a theoretical paper.

Findings
The paper identifies challenging steps in the practical application of C-OAR-SE and suggests that these can be overcome by developing detailed guidelines.

Research limitations/implications
Improving marketing measurement practice is of importance to marketing scholars.

Originality/value
The paper suggests how measure development could be structured in a manner that would reduce the subjective element of content validity assessment.
Welcome to the desert of the real: reality, realism, measurement, and C-OAR-SE
Authors: Lee Nick , Cadogan John 
Published: November 2016

Purpose
This paper provides a balanced commentary on Rossiter’s paper “How to use C-OAR-SE to design optimal standard measures” in this issue of the “European Journal of Marketing”. It also relates the comments in general to Rossiter’s other C-OAR-SE work and throws light on a number of key measurement issues that seem under-appreciated at present in marketing and business research.

Design/methodology/approach
The authors use conceptual argument based on measurement theory and philosophy of science.

Findings
The authors find that Rossiter’s work makes a number of important points that are necessary in the current stage of development of marketing and social science. However, the authors also find that many of these points are also well made by fundamental measurement theories. When measurement theory is correctly interpreted, the idea of multiple measures of the same thing is not problematic. However, they show that existing social science measurement practice rarely takes account of the important issues at play here.

Practical implications
The authors show that marketing, management and social science researchers need to get better in terms of their appreciation of measurement theory and in their practices of measurement.

Originality/value
The authors identify a number of areas where marketing and social science measurement can be improved, taking account of the important aspects of C-OAR-SE and incorporating them in good practice, without needlessly avoiding existing good practices.
Safeguarding adults: from realism to ritual
Authors: Yoeli Heather , Lonbay Sarah P. , Morey Sarah , Pizycki Lara 
Published: November 2016

Purpose
The landscape of adult social care, and in particular of adult safeguarding, has shifted considerably over the last decade. Alongside policy changes in the responses to adult abuse, there have been shifts in professional and public understanding of what falls within the remit of this area of work. This results, arguably, in differing understandings of how adult safeguarding is constructed and understood. Given the increasing emphasis on multi-agency inter-professional collaboration, service user involvement and lay advocacy, it is important to consider and reflect on how both professionals and lay people understand this area of work. The paper aims to discuss these issues.

Design/methodology/approach
This study employed Augusto Boal’s model of Forum Theatre to explore how a variety of professional and lay groups understood, related to and engaged with how the Care Act 2014 defines and describes “adult safeguarding”.

Findings
Lay participants responded to the scenario in a variety of ways, upholding the construct validity of “adult safeguarding” and the authority of the social worker. Social care and health practitioners sought orderly, professionalised and sometimes ritualistic solutions to the “adult safeguarding” scenario presented, seeking carefully to structure and to manage lay involvement. Inter-professional collaboration was often problematic. The role of lay advocates was regarded ambiguously and ambivalently.

Originality/value
This paper offers a number of practice and research recommendations. Safeguarding practitioners could benefit from more effective and reflexive inter-professional collaboration. Both practitioners and service users could benefit from the more thoughtful deployment of the lay advocates encouraged within the Care Act 2014 and associated guidance.
Convergence between direct and indirect real estate investments
Authors: Ekemode Benjamin Gbolahan , Olaleye Abel 
Published: November 2016

PurposeThis paper aimed to examine the return/risk performance of direct and indirect real estate (listed property stock) in the Nigerian real estate market and analyzed the short-term integration between the two classes of real estate assets. It also established whether investors could achieve diversification benefits by combining both assets in a portfolio.Design/methodology/approachThe data utilized comprised annual returns on direct real estate calculated from the rental and capital values of 226 direct commercial properties obtained from property valuers in Lagos, Nigeria, for a period of January 1999-December 2014. The appraisal-based direct real estate returns were de-smoothed using the Geltner (1993) procedure. The annual returns of indirect real estate were also computed from the transactions of listed property stock on the Nigerian Stock Exchange for the study period. The return-risk profiles were also broken down into short- and medium-term sub-periods, comprising 3, 5, 8 and 12 years to reflect the level of volatility in the market, whereas the nature of the short-term relationship between the two real estate assets classes was tested using Granger causality technique.FindingsThe results revealed that listed property stock performed better than unsmoothed direct real estate on a risk-adjusted performance basis. The performance profile, however, varies over the different sub-periods considered. Short-term integration analysis showed that there was no bidirectional relationship between direct and listed property stock, implying diversification and risk reduction possibilities in combining both assets with other asset classes in a domestic asset portfolio. Overall, the results confirm the findings of previous study that listed property stocks return is segmented from the direct real estate market upon which its pricing and trading in the stock market are based.Practical implicationsThe conclusion of the study suggests that investors could achieve improved performance by investing in listed property stocks than direct real estate in the Nigerian real estate market. The inclusion of both assets in a domestic mixed-asset portfolio could also be expected to offer diversification and risk reduction benefits.Originality/valueThis is one of the few studies that examine the short-run integration between direct real estate and listed property stocks with a focus on an emerging African market.
Fincen requires financial institutions to obtain beneficial ownership information for legal entity customers
Authors: Sandoval Ignacio , Horn Charles , Hall Melissa 
Published: November 2016

Purpose
To provide an overview of the legal entity customer due diligence rule recently adopted by the Financial Crimes Enforcement Network (FinCEN), a bureau of the US Department of the Treasury.

Design/methodology/approach
This paper provides an overview of the requirements of the legal entity customer due diligence rule as well as some observations regarding the scope of the rule, its interplay with other regulatory requirements, and some of the rule’s ambiguities.

Findings
While the preamble to the new rule suggests that FinCEN was attempting to accommodate industry concerns, the literal terms of the rule may have the opposite effect.

Practical implications
Although financial institutions will have until May 2018 to come into compliance with the rule’s requirements, they should begin developing the infrastructure to support compliance with the rule as soon as possible.

Originality/value
Practical insights into issues that financial institutions may encounter when implementing the rule’s requirements from experienced financial services lawyers.