bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abell-35 Phenomena in Symbiotic Stars: Discovery of 1.2 and 6.4 Day Periods in VV8 (V471 Per)
Authors: Munari U. , Siviero A. , Tamajo E. , Fiaschi M. , Dallaporta S. , Cherini G. , Frigo A. , Castellani F. , Graziani M. , Moretti S. , Tomaselli S. 
Published: March 2017

Abstract
We have collected high precision optical photometry of VV8, so far 782 individual observing runs uniformly distributed over the period 2005 - 2011. This dataset allows us to refine the known long periodicity of VV8 to P = 16.8 yr, with peak-to-valley amplitudes of ΔB = 0.18 and ΔV = 0.14 mag. In addition, we have discovered two new periodicities: 6.431 d (total amplitude ΔB = ΔV = ΔI = 0.05 mag) and 1.185 d (ΔB = 0.022, ΔV = 0.018, ΔI = 0.014 mag). These two short periods are reminiscent of the Abell-35 phenomena displayed by binary nuclei of planetary nebulae that have gone through a common envelope phase. Twice the 6.431 d period would nicely correspond to the double-peaked light-curve that the G5 III star in VV8 would display if its Roche lobe would be ellipsoidally distorted.
A Study of Long-Term Solar Activity at 37 GHz
Authors: Kallunki J. , Lavonen N. , Järvelä E. , Uunila M. 
Published: March 2017

Abstract
In this paper we investigate the solar activity at the radio frequency (37 GHz) using an extensive data series (solar radio maps) from the Metsähovi Radio Observatory. This paper aims to present this unique solar radio map collection to the public knowledge. The data set covers the years from 1978 to 2011 (solar cycles 21–24). We investigate the long-term solar activity on the ground of the distribution of solar radio brightenings and the differential rotation of the Sun.
L3 Dynamics and Poincaré Maps in the Restricted Full Three Body Problem
Authors: Pihajoki Pauli , Herrera-Sucarrat Elisabet , Palmer Phil , Roberts Mark 
Published: March 2017

Abstract
Poincaré maps are a basic dynamical systems tool yielding information about the geometric structure of the phase space of the system. Poincaré maps are however time consuming to compute. In this paper we have analysed and compared two different schemes to compute Poincaré maps in the context of accuracy versus computation time: a Runge-Kutta method of 7th and 8th order and a time transformed geometric method of 6th order. The dynamical system used is the Restricted Full Three Body Problem, with the primaries, an elongated body and a sphere, in a short axis relative equilibrium configuration. Using these Poincar´e maps we have studied the dynamics near the collinear Lagrange point L3, located on the outer side of the elongated body. We present evidence that the L3 point in this system can have saddle-center, stable or complex unstable behaviour depending on system parameters. We further show that when a low accuracy regime that still captures the correct structure of the Poincaré map is considered, the geometric method clearly outperforms the Runge-Kutta method being up to 4 times faster to compute and free from accumulating local errors that smear the structure of the Poincaré maps.
The Use of Multiwavelength Archival Observational Data for Scientific Discoveries: a Case of the Supernova Remnant Cassiopeia A
Authors: Docenko Dmitrijs 
Published: March 2017

Abstract
Most of the high-quality astronomical data after a proprietary period of typically one year are provided to open access, allowing researchers to complement their observations with the archival data in other wavelength bands, thus improving quality of the data analysis. This paper presents one example of such a use - studies of the reverse shock front passing through an oxygen-rich material in the young supernova remnant Cassiopeia A. The paper is based on the contribution to the “Baltic Applied Astroinformatics and Space Data Processing” conference, held on 2012 May 7-8 in Ventspils, Latvia.
Kinematic Modeling of Distant Galaxies
Authors: Kipper Rain , Tempel Elmo , Tamm Antti 
Published: March 2017

Abstract
Evolution of galaxies is one of the most actual topics in astrophysics. Among the most important factors determining the evolution are two galactic components which are difficult or even impossible to detect optically: the gaseous disks and the dark matter halo. We use deep Hubble Space Telescope images to construct a two-component (bulge + disk) model for stellar matter distribution of galaxies. Properties of the galactic components are derived using a three-dimensional galaxy modeling software, which also estimates disk thickness and inclination angle. We add a gas disk and a dark matter halo and use hydrodynamical equations to calculate gas rotation and dispersion profiles in the resultant gravitational potential. We compare the kinematic profiles with the Team Keck Redshift Survey observations. In this pilot study, two galaxies are analyzed deriving parameters for their stellar components; both galaxies are found to be disk-dominated. Using the kinematical model, the gas mass and stellar mass ratio in the disk are estimated.
Optimization of Pistachio Nut Drying in a Fluidized Bed Dryer with Microwave Pretreatment Applying Response Surface Methodology
Authors: Amiri Chayjan Reza , Kaveh Mohammad , Dibagar Nesa , Zarrin Nejad Moein 
Published: March 2017

Abstract
Thin-layer drying kinetics of pistachio nuts were examined experimentally as a function of drying conditions in a fluidized bed dryer with microwave pretreatment. Four drying specifications of diffusivity, shrinkage, specific energy consumption and total color change were calculated and the effects of parameters were studied. Numerous experimentations were conducted at three levels of air temperature (40, 55, 70 °C), air velocity (1.2, 2.93, 4.01 m/s), and microwave power (270, 450, 630 W). The variation ranges of diffusivity, shrinkage, energy consumption and color change were recorded from 5.01×10–10 to 5.07×10–9 m2/s, from 26.95 % to 13.13 %, from 1.04 to 9.23 kWh and from 10.44 to 17.17, respectively. According to response surface methodology, optimum condition of drying process occurred at microwave power of 630, air temperature of 70 ˚C, and air velocity of 1.2 m/s. In this optimum point, the values of diffusivity, shrinkage, specific energy consumption and total color change were 4.865×10–9, 14.22 %, 2.164 kWh and 12.312, respectively.
A new facile way for the preparation of 3-formylcoumarins
Authors: Bochkov Andrei Y. , Akchurin Igor O. , Traven Valerii F. 
Published: March 2017

Abstract
3-Formylcoumarins 2 are formed as single products in high yields upon reduction of 3-cyanocoumarins 1 with Raney nickel in formic acid. The starting materials 1 are easily accessible by Knoevenagel condensation of commercially available salicylaldehydes.
Anti-inflammatory effects and anti-oxidant capacity ofMyrathius arboreus(Cecropiaceae) in experimental models
Authors: Oluwole Oluwafemi Gabriel , Ologe Olufunmilayo , Alabi Akinyinka , Tunde Yusuf Ganiyu , Umukoro Solomon 
Published: March 2017

AbstractBackground:Inflammation is involved in various diseases; search for safe treatments is warranted. Anti-inflammatory effects of ethanol extract ofMyrathius arboreus(EEMa) were studied in carrageenan-induced model, formaldehyde sub-acute-induced model, and in 48 h lipopolysaccharide-induced air pouch model of inflammation. EEMa membrane-stabilizing activities and anti-oxidant capacity were determined in vitro.Methods:In the carrageenan model EEMa (125, 250, or 500 mg/kg), indomethacin (5 mg/kg), or vehicle 3 mL/kg was administered orally in rats (n=5). After 1 h, 0.1 mL of 1% carrageenan was injected into the right hind paw of rats. Change in edema sizes was measured for 3 h with plethysmometer. One-tenth milliliter (0.1 mL) of 2.5% formaldehyde was injected into the rat paw on the first day and the third day to induce sub-acute inflammation; changes in the edema sizes were determined, and percentages of inhibitions were calculated. Anti-inflammatory effects of EEMa were further examined in lipopolysaccharide (LPS)-induced air-pouch based on leukocytes count, volume of exudates, levels of malondialdehyde, glutathione, superoxide dismutase, nitric oxides, and tumor necrosis factor released into the inflammatory fluids. EEMa-free radicals scavenging activities were studied in DPPH and reducing power tests. Membrane-stabilizing activities of EEMa were evaluated in the red blood cell lysis induced by thermal and hypotonic solution.Results:EEMa (250, 500 mg/kg) produced significant (p<0.001; p<0.05) inhibition of inflammation when compared with vehicle. Also, EEMa (250, 500, or 1000 μg/mL) significantly stabilized membrane and produced free radical scavenging activities.Conclusions:M. arboreuspossesses anti-inflammatory and the anti-oxidant properties that might benefit translational medicine.
Crystal structure of 2,3-diphenyl-1-[(dipropylamino)acetyl]-1,3-diazaspiro[4.5]decan-4-one, C28H37N3O2
Authors: Hassan Rasha M. , Ghabbour Hazem A. , Aboul-Enein Mohamed N. , El-Azzouny Aida A. , Saleh Ola A. , Attia Mohamed I. 
Published: March 2017

Abstract
C28H37N3O2, monoclinic, P21/c (no. 14), a = 11.0454(4) Å, b = 21.9125(8) Å, c = 11.6544(4) Å, β = 111.783(1)°, V = 2619.33(16) Å3, Z = 4, Rgt(F) = 0.0658, wRref(F2) = 0.1940, T = 293(2) K.
Adaptation to mid-season drought in a sweetpotato (Ipomoea batatas [L.] Lam) germplasm collection grown in Mozambique
Authors: Makunde Godwill S. , Andrade Maria I. , Ricardo Jose , Alvaro Abilio , Menomussanga Joana , Gruneberg Wolfgang 
Published: March 2017

Abstract
Drought has negative effects on sweetpotato production. Two experiments with two watering treatments (irrigated and water-stressed) were conducted at Umbeluzi Research Station in 2015. The objectives were to (i) determine response of 48 sweetpotato germplasms to mid-season drought, (ii) determine best traits for improvement of storage root yield under mid-season drought and (iii) assess the selection criteria for identifying drought tolerance in sweetpotato germplasms. The irrigated and water- stressed trials received 640 and 400 mm of water, respectively, throughout the season. Water stress was imposed from 30 to 70 days after planting. Each treatment had two replicates arranged in a randomized complete block design. Data collected on storage root and vine yield and derived drought tolerance indices including harvest index were subjected to analysis of variance in R. Sweetpotato germplasms with high storage root yield under mid-season drought were associated with a high harvest index. Harvest index stability and the geometric mean are key to identifying cultivars with high and stable storage root yield under both treatments. MUSGP0646-126, Irene and Ivone combined both low TOL, SSI, HI and high yield storage root yield across the treatments and over seasons. The use of drought and harvest indices is encouraged for selecting improved cultivars for varied production environments and their regular use in accelerated breeding schemes is suggested.
Aristophanes’ Komödien als Lesetexte
Authors: Zogg Fabian 
Published: March 2017

AbstractIn current research, strongly marked by ‘performance studies’, it is often forgotten that there are at least two approaches in literary research that must concentrate on the reading of Aristophanes’ comedies: As his plays were read for centuries and still are, it is legitimate to pose research questions on the aesthetics of reception and of influence which address the reading of his text. The present paper will argue, further, that Aristophanes’ comedies were conceived right from the start as reading texts. Investigations of their reading are therefore all the more desirable as a complement to ‘performance studies’. In the argument presented here, first the conditions of reading in Aristophanes’ time are sketched out (1). Then it is shown how the poet of comedy was himself a reader, who may have expected a read reception of his own poetic compositions (2). The final part of the paper describes Aristophanes’ environment and asks who may have been among his readership.
Inline surface topography measurements of ultrashort laser pulsed
manufactured micro structures based on low coherence interferometry
Authors: Kunze Rouwen , Schmitt Robert 
Published: March 2017

Abstract
In view of ever-increasing demands on process accuracies and
increasingly narrow tolerance windows in laser micro structuring, the
monitoring of laser processes and the subsequent quality assurance of
the laser-structured products are becoming more and more
important. Functional surface structures to be manufactured by laser
micro structuring are nowadays in the range of 50 μm down
to 10 μm regarding their surface geometries. To cover this
demand, this paper deals with the development of a holistic approach
to scanner-based, coaxial topography measurement by the integration of
a highly accurate inline measuring system into the existing optics of
a laser micro machining system. The combination and implementation of
the laser processing beam and the measuring beam by the same optics is
intended to open up the possibilities of real-time process feedback of
the measurement data for the realization of an adaptively controlled
laser micro structuring process. Therefore, the influence of the
individual system components of the laser beam path on the measurement
beam and induced optical aberrations gets evaluated and
explained. Resulting from this, solutions for improving the system
against these aberrations are developed and evaluated in
a demonstrator setup, implementing the measurement system coaxially
into a laser micro machining beam path.
A homozygous mutation of GNRHR in a familial case diagnosed with polycystic ovary syndrome
Authors: Caburet Sandrine , Fruchter Ronit Beck , Legois Bérangère , Fellous Marc , Shalev Stavit , Veitia Reiner A 
Published: March 2017

Context
PCOS is a heterogeneous condition characterized by hyperandrogenism and chronic anovulation and affects about 10% of women. Its etiology is poorly known, but a dysregulation of gonadotropin secretion is one of its hallmarks.

Objective
As the etiology of PCOS is unclear, we have performed a genome-wide analysis of a consanguineous family with three sisters diagnosed with PCOS.

Methods
Whole-exome sequencing and Sanger sequencing confirmation.

Results
Whole-exome sequencing allowed the detection of the missense variant rs104893836 located in the first coding exon of the GNRHR gene and leading to the p.Gln106Arg (p.Q106R) substitution. Sanger sequencing of all available individuals of the family confirmed that the variant was homozygous in the three affected sisters and heterozygous in both parents.

Conclusions
This is the first description of a GNRHR gene mutation in patients diagnosed with PCOS. Although we do not exclude a possible interaction of the identified variant with the genetic background and/or the environment, our result suggests that genetic alterations in the hypothalamo–pituitary axis may play role in the pathogenesis of PCOS.
Syndecan 1 represses cell growth and FSH responsiveness in human granulosa cells
Authors: Colombe Simon , Houllier Laura , Fleurot Emmanuelle , Levallet Guénaëlle , Benhaïm Annie , Bonnamy Pierre-Jacques , Levallet Jérôme 
Published: March 2017

Albeit devoid of intrinsic catalytic activity, the transmembrane heparan sulphate proteoglycan syndecan 1 plays critical roles in cellular processes such as extracellular matrix crosstalk, cytoskeletal organization, cell spreading, proliferation and differentiation. During the ovarian cycle, the expression of syndecan 1 in granulosa cells shows cyclic variation suggesting that it might fulfil specific roles in follicle development. To investigate its physiological roles on granulosa cells, syndecan 1 was overexpressed in human granulosa cell line KGN which retains features of granulosa cells from small antral follicle such as estradiol (E2) synthesis and low expression of functional FSH receptor (FSHR). We demonstrated that overexpression of syndecan 1 in immature granulosa cells (KGN-SDC1) induces a profound alteration in their intrinsic characteristics including enhanced spreading and attachment, both associated with a reduced growth rate. Flow cytometry analysis revealed that syndecan 1 overexpression increases the percentage of KGN cells in quiescent phase. This partial cell cycle exit is concordant with downregulated levels ofCCND1andCDK4and upregulated expression of CDK inhibitorCDKN1A. In parallel both unstimulated and FSH-induced E2 synthesis are reduced in KGN-SDC1 through both repression ofCYP19A1andFSHRmRNA associated with decreased levels of potential regulatorsNR5A1andESR2. Additionally, we provide evidence that transient cAMP accumulation reduction in cells overexpressing syndecan 1 is accompanied by an increase in cAMP-hydrolysing PDE activity. Our results demonstrated that syndecan 1 might regulate differentiation of granulosa cells and follicular development by means of various mechanisms involving morphological changes, control of signalling pathways and alterations in gene expressions.Free French abstract: A French translation of this abstract is freely available athttp://www.reproduction-online.org/content/153/6/797/suppl/DC2
O cinema brasileiro diante de um presente incendiário: o filme O Caso dos Irmãos Naves (1967), de Luís Sérgio Person, e o despertar das consciências durante o regime de exceção
Authors: Silva Jaison Castro 
Published: March 2017

O artigo analisa as diversas opiniões sobre o filme O Caso dos Irmãos Naves (1967), de Luís Sérgio Person, contidas na crítica cinematográfica da época da estreia do filme, que mobilizaram questões humanistas fundamentais, principalmente no que diz respeito à abordagem das violentas cenas de tortura, muitas vezes acusadas de sadismo, existentes naquela película. Em meio à discussão sobre a narrativa cinematográfica e às possibilidades de apagamento do cineasta frente à representação documental da verdade, despontava o debate sobre como as formas imagéticas de produção de sentido podem mobilizar sentimentos e/ou acionar consciências de maneira política. A abordagem histórica, a partir de referências como Walter Benjamin e Giorgio Agamben, insere-se na discussão sobre visualidade, investigando como, apesar de um quadro de referências comum, o período apresentava diferentes formas de acionar as imagens.
THE ROLE OF INFLAMMATORY CYTOKINES IN THE INITIATION AND COURSE OF ACNE: A MODERN VIEW
Authors: Kormilitcyna A. V. , Kalinina N. M. 
Published: March 2017

The publication provides an overview of current scientific and medical literature devoted to the study of mechanisms of immunopathogenesis of acne. The concept of the pathophysiology and immunopathogenesis of acne expanded significantly in recent years, many scientists have pointed out the link between the presence of acne and disorders of the endocrine, nervous, digestive and immune systems. Despite the fact that the individual links in the pathogenesis of acne are well studied, there are still questions about the role of commensal Propionibacterium acnes in the initiation and development of acne. So far there is no information on the number of P. acnes in healthy and diseased skin, the relationship between the numder of P. acnes and severity of the disease, also an important question remains unanswered — why do P. acnes cause inflammation for some people, while it don`t for the others? Despite the presence of bacterial factor in the pathogenesis of acne, there are a large number of studies showing that the nature of the patient’s immune response to P. acnes is more important than the infectious agent. For quite a long time data was received that proinflammatory cytokines play an important role in the initiation of acne. Interleukins IL-6 and IL-8 are involved in the stimulation of sebum hypersecretion, and subpopulation Th1 derived from a patient with acne, recognize P. acnes antigens. A number of recently obtained results suggest that P. acnes is a potent inducer of Th17 and Th1, and the study of the role of proinflammatory cytokines in the development of acne suggests new possibilities of acne therapy. Presented in this article is a clinical case clearly illustrates the part of the immune inflammation in acne. Prospective areas of research on the role of signaling molecules in the pathogenesis of acne are covered: such as the mechanism of action of nitric oxide on the secretion of interleukin IL-1 beta, which was shown as a dominant etiological factor in acne vulgaris, as well as an attempt to establish a link between the concentration of the neuropeptide substance P in the serum and the intensity psychological stress in the patients with acne in comparison with those in healthy persons. From the presented literature review it is shown that the immunopathogenesis of acne itself, as well as its connection with disturbances of the nervous, endocrine and digestive systems are the subject of intensive study of both dermatologists and clinical immunologists, who are inquired by patients with acne.
Characterisation of vumba and ubumba clays used for cosmetic purposes
Authors: Morekhure-Mphahlele Refilwe , Focke Walter W. , Grote Wiebke 
Published: March 2017

Two traditional cosmetic clays bear similar names in different local South African languages: vumba (Tshivenda) and ubumba (isiZulu). The wet clays are applied topically for cosmetic purposes by the respective indigenous peoples. Six samples from two South African provinces were characterised using X-ray diffraction, X-ray fluorescence spectroscopy, Fourier transform infrared spectroscopy, thermal gravimetric analysis and scanning electron microscopy. It was found that the samples differed widely with respect to mineralogy and chemical composition. This finding raises the possibility that texture characteristics during application on the skin override composition effects. Of concern is the high levels of quartz found in all the samples as it might pose a health hazard; the lowest value for quartz was 11 wt% for vumba, while values for ubumba ranged from 26 wt% to 85 wt%. All samples contained varying amounts of silicates in the form of smectite, kaolin, chlorite and plagioclase. Minor amounts of anatase and rutile were present in some samples. Three samples also contained goethite. All samples were essentially free from the toxic elements As, Pb, Hg, Cd, Se and Sb. However, they did contain low levels of chromium and heavy metals such as Cu, Zn and Ni. The pH values of ubumba slurries were slightly basic, while those of a vumba slurry were slightly acidic.

Significance:

Wide ranges of composition appear to be acceptable.
The clays do not contain highly toxic or radioactive elements.
The high levels of quartz present may pose a human health risk.