bluuebunny/crossref_metadata_2025_split huggingface dataset:
O jogo como recurso pedagógico – Ser, comunicar, interagir, construir conhecimento
Authors: Lamas Estela Pinto Ribeiro 
Published: November 2015

Cientes de que o jogo faz emergir e enriquecer a cultura do lúdico, com este simpósio, exploramos formas em que as atividades rotineiras podem ser transformadas em jogo(s) que traga(m) ao(s) sujeito(s) implicado(s) ótimas experiências de aprendizagem. Referimo-nos, pois, ao recurso à ludicidade, à construção de uma cultura que foge à rotina e à instrumentalização, que promove o envolvimento do aluno numa atividade, pelo prazer que esta lhe possa trazer, contribuindo desse modo para que o aluno possa assumir a sua identidade, isto é, ser, comunicar, interagir, construir conhecimento. Assente na problematização exposta, num primeiro momento, contextualizando as ideias apresentadas, são abordadas as teorias que sustentam a opção pelo jogo como recurso pedagógico e questionadas as suas fundamentações científico-pedagógicas. Num segundo momento, surgem cinco boas práticas do uso do jogo em contexto educativo. A primeira focaliza o jogo no campo das expressões integradas, revelando o seu potencial sócio-lúdico, explorando estratégias diversificadas que proporcionam o trabalho individual, em grupos e em comunidade. A segunda centra-se do drama e questiona o seu contributo para a educação e desenvolvimento da criança, a forma como a impele a autodescobrir-se, a partilhar as suas opiniões e emoções, servindo pois para a sua socialização. A terceira apresenta a vivência de um projeto que evidencia o contributo da música para a formação holística da criança, mostrando como o envolvimento se processa em todo o seu esplendor, pelo canto, pela dança, pela audi(a)ção, pelo jogo e pela leitura. A quarta explora a potencialidade da poesia para a promoção do desenvolvimento holístico da criança, anunciando a apresentação de atividades que ajudaram um grupo de crianças a despertar os seus sonhos e a sua imaginação, ancorando-se na realidade. Ao longo do simpósio serão levantadas questões que induzam a uma discussão construtiva sobre o potencial pedagógico do jogo para uma educação inclusiva e geradora de vivências interculturais positivas.
Influences of pin profile on the macrostructure and mechanical properties of friction stir welded AA6061-T6 alloy T-joints
Authors: Alamdari Majid , Saeidi Mehdi , Manafi Babak , Masoumi Abolfazl , Ghowsi Kavan 
Published: November 2015

Abstract
Friction stir welding is a solid-state process in which the joining operation is performed while the base materials are not melted and they are merely plasticized. In this study, friction stir welding of the AA 6061-T6 aluminum alloy T-joint has been studied and the influences of the tool pin profile on the macrostructure and mechanical properties of the joints have been investigated. Accordingly, three different pin profiles, such as straight cylindrical, taper cylindrical and square have been utilized. Then the joints have been examined using macroscopic images. Also, the joints have been investigated by tensile and hardness tests. As obtained from the results, the fabricated joints by the cylindrical pin exhibited the maximum tensile strength and hardness due to the homogeneity of material flow and the lack of defects.
Effect of homogenization heat treatment on toughness and wear resistance of plastic mold steel
Authors: Çöl Mustafa , Koç Funda Gül 
Published: November 2015

Abstract
In this study, the effect of homogenization treatment on the microstructure, toughness and wear resistance of plastic mold steel was investigated. Homogenization heat treatment was performed at 1150 °C for 3 hours. All specimens were austenitized at 850 °C for 1 hour, quenched in oil and tempered at different temperatures. Wear tests were carried out using a pin-on-disc tribometer under dry sliding conditions. Charpy V notch impact tests were performed to determine the toughness properties. Microstructure, fracture and worn surfaces were investigated by scanning electron microscope. The results show that heat treatment conditions have an effect on the microstructure and mechanical properties of materials. It was determined that homogenization heat treatment causes more homogeneous structure, in particular, it has a positive effect on the toughness properties and wear resistance of the materials which were tempered at low temperatures.
Milling behavior of Hadfield steel with cryogenically treated tungsten carbide inserts
Authors: Ekici Ergün 
Published: November 2015

Abstract
In this study, the performance of cryogenically treated tungsten carbide inserts in the milling of Hadfield steel (X120Mn12) was evaluated in terms of surface roughness (Ra) and tool wear (VB). Cutting tools were assessed under three conditions: untreated (U), cryogenic treated (CT) and cryo-tempered (CTT). For the cutting parameters, three different cutting speeds (70, 100 and 130 m·min−1) and feed rates (0.08, 0.14 and 0.2 mm·rev−1) were used. The experiments were carried out under a fixed depth of cut and dry cutting conditions. To determine the factorial effects, the procedure Taguchi L27 (33) was used. For the estimation of Ra and VB, the response surface method (RSM) was employed and mathematical models were developed. In terms of Ra, the effective parameter was feed rate (89.45 %) and in terms of VB, it was the cutting speed (60.42 %). For Ra and VB, the optimum levels of factors were determined as A3B3C1 and A3B1C1, respectively. The effects of the factors were also assessed by RSM.
Du contexte villageois au village global
Authors: Milazzo Josepha 
Published: November 2015

Répondre à une problématique, c’est présenter des résultats de recherche de sorte qu’ils résolvent un problème, géographique ici en l’occurrence, en vue d’apporter une contribution théorique. Cet objectif appelle la mise en œuvre d’une méthodologie rigoureusement pensée (Huff, 1999 ; Booth, Colomb et Williams, 2008 ; Pierre, 2009 ; Turabian, 2013). À l’aune de ma participation à diverses rencontres scientifiques portant sur les méthodologies et les méthodes de recherche dans les études migratoires, j’ai pu constater qu’un point récurrent semblait ressortir dans les critiques faites aux participants, suite à l’exposé de leurs analyses. La plupart des chercheurs évoquaient, au gré de leurs expériences, la spécificité de leur terrain et de la construction de leur sujet de recherche, semés d’embuches. Toutefois, nous sommes difficilement à l’aise avec la formulation explicite des répercussions concrètes de ces expériences dans les données collectées, dans la manière de les collecter ou encore dans les analyses que nous en faisons. Ces allers-retours conduisent pourtant à de multiples reformulations dans nos recherches. C’est à ce titre que des travaux dans les études migratoires soulignent l’importance de la réflexivité dans la recherche, pour soumettre au mieux à la critique la production du savoir en sciences humaines et sociales, « la crédibilité des procédés selon lesquels les informations factuelles et les interprétations significatives ont été collectées et produites » (DeWind, 2007, 9). J’aimerais précisément joindre une discussion sur l’importance de l’approche réflexive. Mon sujet de recherche a connu un changement de focus important au gré de mon cheminent intellectuel et en réaction aux premiers terrains que j’ai effectués. J’ai à cette occasion recentré mon intérêt sur une seule partie de mes objectifs initiaux. Mon parcours méthodologique a ainsi évolué selon les ajustements nécessaires et possibles à la réalisation de ces objectifs. Je propose de revenir sur ces étapes de construction de ma thèse. Ce processus s’est voulu itératif, entre empirie et théorie.
Comparer deux espaces urbains du commerce transnational (Le Caire et Oran), ou comment gérer les écarts entre théorie de la comparaison et pratique sur le terrain
Authors: Bouhali Anne 
Published: November 2015

<p class="resume">L’article proposé revient sur la méthodologie de la comparaison adoptée et développée en vue de la réalisation d’une thèse en géographie. Notre thèse propose d’analyser la constitution de dispositifs urbains commerciaux sur les routes de la « mondialisation discrète » (Pliez, 2007) entre Afrique du Nord et Asie du Sud-est, dans deux villes du monde arabe, Le Caire en Égypte et Oran en Algérie. La présente contribution a pour objectif de décortiquer les apports à la fois théoriques et pratiques de la comparaison en géographie, mais aussi d’en soulever les difficultés rencontrées par le jeune chercheur lors de sa mise en pratique sur le terrain et lors de l’écriture.</p>
Le commerce ethnique dans les espaces marchands de Château Rouge (Paris) et Brixton (Londres)
Authors: Mung Guillaume Ma 
Published: November 2015

<p class="resume">Cet article a pour objectif d’étudier des processus d’appropriation de l’espace inhérents à l’implantation de commerces ethniques dans les quartiers de Château Rouge à Paris et de Brixton à Londres. Il se concentre sur les modalités selon lesquelles ce commerce, qui implique des populations d’origine africaine et antillaise, peut conditionner la visibilité de ces groupes au sein de l’espace urbain, et plus largement de la société d’accueil. Spécifiquement, il s’agit de privilégier l’étude de marqueurs symboliques attachés à l’espace par les pratiques inhérentes au commerce ethnique. Notre recherche tâchera de montrer que son implantation à Château Rouge et à Brixton produit différentes configurations spatiales et implique différents processus d’appropriation de l’espace. Nous verrons ainsi que le commerce ethnique entraine une variété de références à un « ailleurs » géographique et culturel dans l’espace urbain et de discours en rapport avec sa visibilité et celle des groupes migrants concernés.</p>
Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance
Authors: Skeldon Alexander M. , Morizot Alexandre , Douglas Todd , Santoro Nicola , Kursawe Romy , Kozlitina Julia , Caprio Sonia , Mehal Wajahat Z. , Saleh Maya 
Published: November 2015

Abstract
Inflammation is well established to significantly impact metabolic diseases. The inflammatory protease caspase-1 has been implicated in metabolic dysfunction; however, a potential role for the related inflammatory caspases is currently unknown. In this study, we investigated a role for caspase-11 and caspase-12 in obesity and insulin resistance. Loss of caspase-12 in two independently generated mouse strains predisposed mice to develop obesity, metabolic inflammation, and insulin resistance, whereas loss of caspase-11 had no effect. The use of bone marrow chimeras determined that deletion of caspase-12 in the radio-resistant compartment was responsible for this metabolic phenotype. The Nlrp3 inflammasome pathway mediated the metabolic syndrome of caspase-12–deficient mice as ablation of Nlrp3 reversed Casp12−/− mice obesity phenotype. Although the majority of people lack a functional caspase-12 because of a T125 single nucleotide polymorphism that introduces a premature stop codon, a fraction of African descendents express full-length caspase-12. Expression of caspase-12 was linked to decreased systemic and adipose tissue inflammation in a cohort of African American obese children. However, analysis of the Dallas Heart Study African American cohort indicated that the coding T125C single nucleotide polymorphism was not associated with metabolic parameters in humans, suggesting that host-specific differences mediate the expressivity of metabolic disease.
Sertraline induced acute mandibular dystonia
Authors: Raveendranathan Dhanya , Rao Swaminath 
Published: November 2015

ABSTRACTSpecific serotonin reuptake inhibitors have been linked with the occurrence of drug-induced parkinsonism, dystonia, dyskinesia, and akathisia. Here, we describe a patient with a diagnosis of emotionally unstable personality disorder and depression who developed severe mandibular dystonia with sertraline in the absence of concurrent prescription of medications, which have potential action on the dopaminergic system. This case highlights the need for clinicians to be aware of this alarming acute adverse effect with sertraline, which is conventionally considered to be well-tolerated and safe.
Remote multiple intracranial hemorrhage in multiple metastatic lung adenocarcinoma following decompression of posterior fossa lesion: Unknown cause
Authors: Konar Subhas , Babu R. Arun , Shukla Dhaval P. , Devi B Indira 
Published: November 2015

ABSTRACTCerebral metastasis can present with hemorrhage. However, multiple hemorrhages in metastatic lesions following surgical decompression of a single lesion are never reported. We report a case of cerebral metastasis from lung cancer that developed multiple hemorrhages in supratentorial metastatic lesions following surgical resection of an infratentorial lesion.
An Embedding into a Substructure of the r.e. Turing Degrees
Authors: Cintioli Patrizio 
Published: November 2015

Let $(I_m,\le)$ be the partial ordering of the $m$-introimmune r.e. Turing degrees.We wonder if such structure is an upper semi-lattice. We give a partial answer, by embedding some Boolean algebras in $(I_m,\le)$.
De OK kiest voor een historische peildatum bij uitkoopprocedures
Authors: Schotel O.J.W. 
Published: November 2015

De OK kiest voor een historische peildatum bij uitkoopprocedures
Sinds 2000 nam de Ondernemingskamer in uitkoopprocedures haar eindarrest als peildatum voor de bepaling van de uitkoopprijs. In het arrest inzake Unit4 (7 juli 2015) komt de OK terug van dit uitgangspunt. Vanaf heden wordt een peildatum in het verleden gebruikt. Na een openbaar bod is de dag van betaalbaarstelling de peildatum.
De verschuivende functies van de Awb
Authors: Schueler B.J. 
Published: November 2015

De verschuivende functies van de Awb
Deze bijdrage gaat aan de hand van de Algemene wet bestuursrecht (Awb) in op een van de drie hoofdcategorieën van rechtseenheid die Stip en Zijlstra onderscheiden, namelijk de rechtseenheid die ziet op het voorkomen van verschillende uitleg en toepassing van dezelfde rechtsnormen binnen een rechtsorde. De auteur bespreekt de vijf belangrijkste redenen om algemene regels van bestuursrecht in de Awb op te nemen in plaats van een regeling te maken voor deelterreinen. Hij bespreekt deze redenen vanuit vijf invalshoeken: rechtseenheid, kenbaarheid, voorspelbaarheid, efficiëntie van wetgeving en borging van rechtsstatelijkheid. In het huidige tijdsgewricht zijn met name die laatste twee van belang door twee ontwikkelingen. Ten eerste proberen bestuur en wetgevers de slagkracht van het bestuur te vergroten. De Awb waarborgt dat burgers de middelen houden die nodig zijn om voor hun belangen en rechten op te komen. Ten tweede komt door verschuivingen het zwaartepunt in wetgeving steeds meer bij het bestuur te liggen: normstelling wordt meer bestuurlijk ingekleurd, de rechter wordt op afstand gezet en de wetgever laat inhoudelijke regelgeving over aan het bestuur. Dit werpt een nieuw licht op de waarborgfunctie van de Awb, die het handelen van het bestuur normeert.
Regelgeving in de wereld van digitale platformen
Authors: Ranchordás S.H. 
Published: November 2015

Regelgeving in de wereld van digitale platformen
De komst van digitale platformen heeft consumptie, werk en en handel drastisch veranderd. De auteur gaat in op de voordelen van digitale platformen in het kader van de deeleconomie, namelijk dat zij innovatieve, handige en betaalbare diensten en producten bieden die onze levens vergemakkelijken. Het is vooralsnog onduidelijk wat de invloed is van de deeleconomie op wet- en regelgeving. De deeleconomie kan maatschappelijke belangen dienen, zoals de applicatie ‘Vluchtelingen-welkom’ illustreert, maar het kan ook gaan om commerciële belangen. Dat brengt zeker nadelen met zich mee, maar daardoor mogen de voordelen van de deeleconomie niet vergeten worden.
Voorhangprocedures voor inwerkingtredingsbesluiten: een staatsrechtelijk gedrocht?
Authors: Borman T.C. 
Published: November 2015

Voorhangprocedures voor inwerkingtredingsbesluiten: een staatsrechtelijk gedrocht?
Sinds de eeuwwisseling lijkt een fenomeen in opkomst dat wat de juridische vormgeving betreft gelijkenis vertoont met parlementaire betrokkenheid bij gedelegeerde wetgeving, maar bij nadere beschouwing toch heel wat anders is: voorhangprocedures voor koninklijke besluiten waarmee een wet in werking wordt gesteld. Op het eerste gezicht lijkt dat vreemd: als de Tweede en Eerste Kamer een wet aannemen, mag toch worden verondersteld dat zij ook willen dat de wet in werking treedt. Maar zo simpel blijkt dat toch niet te zijn. De wet wordt dan weliswaar door de Tweede en Eerste Kamer aangenomen, maar zij behouden zich daarbij uitdrukkelijk het recht voor om te beslissen of en wanneer de wet (of een gedeelte) daarvan) daadwerkelijk effect krijgt. Dit is een nieuw fenomeen, dat staatsrechtelijk bijzonder is te noemen. Immers, de behandeling van een wet in de Tweede en Eerste Kamer kan daarmee eigenlijk nog een keer worden overgedaan. De aanvaarding in de Tweede en Eerste Kamer krijgt daarmee slechts het karakter van een voorwaardelijk groen licht. De inwerkingtreding van de wet is formeel gesproken niet langer een vanzelfsprekend sequeel van de totstandkoming ervan. Sinds 2001 zijn er op dertien wetsvoorstellen amendementen ingediend waarin een voorhangprocedure voor een inwerkingtredingsbesluit werd voorgesteld. Daarnaast zijn er twee gevallen waarin de regering het initiatief nam. Al deze gevallen worden in het artikel besproken en van enkele conclusies voorzien.
Sphere-Derived Multipotent Progenitor Cells Obtained From Human Oral Mucosa Are Enriched in Neural Crest Cells
Authors: Abe Shigehiro , Yamaguchi Satoshi , Sato Yutaka , Harada Kiyoshi 
Published: November 2015

Abstract

Although isolation of oral mucosal stromal stem cells has been previously reported, complex isolation methods are not suitable for clinical application. The neurosphere culture technique is a convenient method for the isolation of neural stem cells and neural crest stem cells (NCSCs); neurosphere generation is a phenotype of NCSCs. However, the molecular details underlying the isolation and characterization of human oral mucosa stromal cells (OMSCs) by neurosphere culture are not understood. The purpose of the present study was to isolate NCSCs from oral mucosa using the neurosphere technique and to establish effective in vivo bone tissue regeneration methods. Human OMSCs were isolated from excised human oral mucosa; these cells formed spheres in neurosphere culture conditions. Oral mucosa sphere-forming cells (OMSFCs) were characterized by biological analyses of stem cells. Additionally, composites of OMSFCs and multiporous polylactic acid scaffolds were implanted subcutaneously into immunocompromised mice. OMSFCs had the capacity for self-renewal and expressed neural crest-related markers (e.g., nestin, CD44, slug, snail, and MSX1). Furthermore, upregulated expression of neural crest-related genes (EDNRA, Hes1, and Sox9) was observed in OMSFCs, which are thought to contain an enriched population of neural crest-derived cells. The expression pattern of α2-integrin (CD49b) in OMSFCs also differed from that in OMSCs. Finally, OMSFCs were capable of differentiating into neural crest lineages in vitro and generating ectopic bone tissues even in the subcutaneous region. The results of the present study suggest that OMSFCs are an ideal source of cells for the neural crest lineage and hard tissue regeneration.

Significance
The sphere culture technique is a convenient method for isolating stem cells. However, the isolation and characterization of human oral mucosa stromal cells (OMSCs) using the sphere culture system are not fully understood. The present study describes the isolation of neural crest progenitor cells from oral mucosa using this system. Human OMSCs form spheres that exhibit self-renewal capabilities and multipotency, and are enriched with neural crest-derived cells. These oral mucosa sphere-forming cells can generate ectopic bone tissue in vivo. Therefore, the results of the present study show that the sphere culture system can be applied, without the need for complex isolation techniques, to produce multipotent spheres with the properties of neural crest stem cells. Furthermore, a convenient strategy is demonstrated for the isolation and culture of human OMSCs that could have clinical applications.
Analysis of structural relationship among the occupational dysfunction on the psychological problem in healthcare workers: a study using structural equation modeling
Authors: Teraoka Mutsumi , Kyougoku Makoto 
Published: November 2015

Purpose.The purpose of this study is to demonstrate the hypothetical model based on structural relationship with the occupational dysfunction on psychological problems (stress response, burnout syndrome, and depression) in healthcare workers.Method.Three cross sectional studies were conducted to assess the following relations: (1) occupational dysfunction on stress response (n= 468), (2) occupational dysfunction on burnout syndrome (n= 1,142), and (3) occupational dysfunction on depression (n= 687). Personal characteristics were collected through a questionnaire (such as age, gender, and job category, opportunities for refreshment, time spent on leisure activities, and work relationships) as well as the Classification and Assessment of Occupational Dysfunction (CAOD). Furthermore, study 1 included the Stress Response Scale-18 (SRS-18), study 2 used the Japanese Burnout Scale (JBS), and study 3 employed the Center for Epidemiological Studies Depression Scale (CES-D). The Kolmogorov–Smirnov test, confirmatory factor analysis (CFA), exploratory factor analysis (EFA), and path analysis of structural equation modeling (SEM) analysis were used in all of the studies. EFA and CFA were used to measure structural validity of four assessments; CAOD, SRS-18, JBS, and CES-D. For examination of a potential covariate, we assessed the correlation of the total and factor score of CAOD and personal factors in all studies. Moreover, direct and indirect effects of occupational dysfunction on stress response (Study 1), burnout syndrome (Study 2), and depression (Study 3) were also analyzed.Results.In study 1, CAOD had 16 items and 4 factors. In Study 2 and 3, CAOD had 16 items and 5 factors. SRS-18 had 18 items and 3 factors, JBS had 17 items and 3 factors, and CES-D had 20 items and 4 factors. All studies found that there were significant correlations between the CAOD total score and the personal factor that included opportunities for refreshment, time spent on leisure activities, and work relationships (p< 0.01). The hypothesis model results suggest that the classification of occupational dysfunction had good fit on the stress response (RMSEA = 0.061, CFI = 0.947, and TLI = 0.943), burnout syndrome (RMSEA = 0.076, CFI = 0.919, and TLI = 0.913), and depression (RMSEA = 0.060, CFI = 0.922, TLI = 0.917). Moreover, the detected covariates include opportunities for refreshment, time spent on leisure activities, and work relationships on occupational dysfunction.Conclusion.Our findings indicate that psychological problems are associated with occupational dysfunction in healthcare workers. Reduction of occupational dysfunction might be a strategy of better preventive occupational therapies for healthcare workers with psychological problems. However, longitudinal studies will be needed to determine a causal relationship.