bluuebunny/crossref_metadata_2025_split huggingface dataset:
Museum specimens shedding light on the evolutionary history and cryptic diversity of the hedgehog family Erinaceidae
Authors: ZENG Ying , HE Kai , CHEN Xing , BAI Weipeng , LIN Hongzhou , CHEN Jianhai , NEDYALKOV Nedko , YAMAGUCHI Nobuyuki , VIJAYAN Keerthy , SUGANTHASAKTHIVEL Ramamoorthy , KUMAR Brawin , HAN Yuqing , CHEN Zhongzheng , WANG Wenzhi , LIU Yang 
Published: October 2024

AbstractThe family Erinaceidae encompasses 27 extant species in two subfamilies: Erinaceinae, which includes spiny hedgehogs, and Galericinae, which comprises silky‐furred gymnures and moonrats. Although they are commonly recognized by the general public, their phylogenetic history remains incompletely understood, and several species have never been included in any molecular analyses. Additionally, previous research suggested that the species diversity of Erinaceidae might be underestimated. In this study, we sequenced the mitochondrial genomes of 29 individuals representing 18 erinaceid species using 18 freshly collected tissue and 11 historical museum specimens. We also integrated previously published data for a concatenated analysis. We aimed to elucidate the evolutionary relationships within Erinaceidae, estimate divergence times, and uncover potential underestimated species diversity. Our data finely resolved intergeneric and interspecific relationships and presented the first molecular evidence for the phylogenetic position of Mesechinus wangi, Paraechinus micropus, and P. nudiventris. Our results revealed a sister relationship between Neotetracus and Neohylomys gymnures, as well as a sister relationship between Hemiechinus and Mesechinus, supporting previous hypotheses. Additionally, our findings provided a novel phylogenetic position for Paraechinus aethiopicus, placing it in a basal position within the genus. Furthermore, our study uncovered cryptic species diversity within Hylomys suillus as well as in Neotetracus sinensis, Atelerix albiventris, P. aethiopicus, and Hemiechinus auratus, most of which have been previously overlooked.
Preparation and characterization of ovomucin self‐assembly nanoparticles under glycerol compression for astaxanthin delivery: Sustained release and antioxidant activity
Authors: Zhang Zhenqing , Li Xuanchen , Teng Haoye , Han Yumeng , Jin Yongguo , Xu Qi 
Published: October 2024

AbstractAstaxanthin (AST) is a natural hydrophobic nutrient with various biological activities, but its low solubility limits its application. In this study, self‐assembly nanoparticles were prepared by ovomucin (OVM) and Ca2+ with the enhancement of glycerol to deliver AST. Glycerol compressed the particle size of nanoparticles from 175.7 ± 1.8 to 142.9 ± 0.6 nm, and the nanoparticles had a strong negative charge (−28.9 ± 0.6 mV). Ultraviolet–visible spectroscopy and X‐ray diffraction (XRD) confirmed the successful encapsulation of AST in an amorphous form with a high encapsulation efficiency (82.9% ± 2.1%). Fourier transform infrared and circular dichroism analyses demonstrated that nanoparticles formation mainly involved electrostatic interactions and hydrophobic interactions. AST in nanoparticles presented excellent gastric juice resistance and sustained release ability, whereas free radical scavenging efficiency reached up to 75%. In addition, the nanoparticles had no apparent toxicity to cell viability. This study is expected to provide a new insight into the safe and efficient delivery of AST, while demonstrating the potential of OVM as a delivery carrier in the food and health industries.
The evolution of Japanese real GDP components in the time–frequency domain: The disappearance of the investment accelerator effect?
Authors: Crowley Patrick M. , Hudgins David 
Published: October 2024

AbstractUnderstanding the interaction between national income GDP expenditure components is a key part of the study of the macroeconomics of any country. The general aim of this study is to explore this interaction between the GDP expenditure components in the time–frequency domain for the country of Japan, obtain some stylized facts and then compare them with those of the United States. The main result shows that the cyclical interactions between consumption and investment are typical of an “accelerator” effect and operate at several different frequencies, but that the several different cycles evident in the data phase out in the 1990s, once secular stagnation started to take hold. We hypothesize that Japan's investment drivers then changed to be dependent on the external sector by the 2000s. A secondary result is that Japanese fiscal policy appears to have been largely ineffective in terms of creating cyclical interactions with other GDP components.
Antecedents of Lead Director Selection
Authors: Li Yajing 
Published: October 2024

ABSTRACTResearch Question/IssueThis paper investigates the antecedents of lead director selection in the US context. Specifically, how do rational and social factors influence the likelihood of being selected as the lead director?Research Findings/InsightsResults for independent directors in S&P 1500 firms from 2000 to 2021 support the positive effect of both board capital (human capital and social capital) and social embeddedness with the CEO (university ties and demographic similarity) as factors in the selection of lead directors. Results also show that among late adopters, the effect of human capital (board experience) on selection is strengthened, and the effect of demographic similarity to the CEO on selection is weakened.Theoretical/Academic ImplicationsFirst, building on the director selection model, this paper further differentiates the rational and socialized perspectives by integrating the diffusion model. Specifically, among late adopters, rational factors play a larger role, and socialized factors play a smaller role in the lead director selection. Second, for the literature on the boards of directors, this paper provides unique individual‐level insights about directors' attributes and their interactions with firm‐level timing of practice adoption.Practitioner/Policy ImplicationsThe new governance practice of having a lead director, a leader of independent directors, has emerged and spread in the United States since 2000. As attention to the lead director governance practice increases, this paper focuses on the complexity of its adoption. Specifically, both rational (board capital) and socialized (social embeddedness with the CEO) factors can play a role in the lead director selection. Related stakeholder groups such as directors, investors, and policymakers should be aware of the potential symbolic adoption of this new governance practice.
Clinical Efficacy of Isatuximab Plus Carfilzomib and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients
Authors: De Novellis Danilo , Derudas Daniele , Vincelli Donatella , Fontana Raffaele , Della Pepa Roberta , Palmieri Salvatore , Accardi Fabrizio , Rotondo Francesco , Morelli Emanuela , Gigliotta Emilia , Roccotelli Daniela , Marano Luana , Barone Maria Lucia , Cetani Giusy , Esposito Daniela , Lazzaro Antonio , Delle Cave Giuseppe , Serio Bianca , Morini Denise , Porrazzo Marika , Urciuoli Eleonora , Masucci Chiara , Fanelli Fulvia , Rizzo Michela , Arcamone Manuela , Trastulli Fabio , Rocco Stefano , Leone Aldo , Bianco Rosario , Salvatore Flavia , Idato Aurora , Sicari Maria , Tosi Patrizia , Rascato Maria Gabriella , Di Perna Maria , Falcone Antonietta Pia , Morello Lucia , Carlisi Melania , Svanera Gino , Annunziata Mario , Frigeri Ferdinando , Califano Catello , Carella Angelo Michele , Marcacci Gianpaolo , Pane Fabrizio , Risitano Antonio Maria , Giudice Valentina , Botta Ciro , Selleri Carmine 
Published: October 2024

ABSTRACTIsatuximab, a novel anti‐CD38 monoclonal antibody, is approved in combination with carfilzomib and dexamethasone (Isa‐Kd) in relapsed/refractory multiple myeloma (RRMM) patients. Because of its recent introduction, real‐world efficacy and safety are poorly reported. In this Italian multicenter real‐life observational retrospective study, efficacy and safety of the Isa‐Kd regimen were evaluated in a cohort of 103 RRMM patients. Overall response rate (ORR) was 85%, with stringent (sCR) or complete response (CR) in 18% of cases and very good partial response (VGPR) in 39%. Median PFS and OS were not reached within the study period, while 1‐year PFS and OS were 72% and 77%, respectively. Hematological toxicities were observed in 42% of subjects, and cardiac toxicities occurred in 24% of cases. Moreover, we conducted a subanalysis on patients (N = 69) treated with Isa‐Kd after one prior line of therapy, showing an ORR of 88%, with sCR + CR in 20% of subjects, VGPR in 46%, and PR in 22% of patients. In this group, median PFS and OS were not reached, while 1‐year PFS and OS were 92% and 95%, respectively. In conclusions, our study confirmed Isa‐Kd as an effective treatment option for RRMM with a manageable safety profile even in real‐life settings.
Kenyan Female Immigrants’ Creation of a Virtual Enclave: The Influence of Age and Immigration Status
Authors: Chenane Joselyne L. , Gonzales Teresa Irene , Pryce Daniel K. 
Published: October 2024

ABSTRACTMuch of the research on ethnic enclaves in the United States has focussed on physical, geographic spaces or brick‐and‐mortar establishments that foster community building and provide shared resources for immigrant groups, such as those from Latin America, Asia and Europe. These studies often highlight the benefits and challenges enclaves provide, with only a limited discussion of how immigrant women use these spaces. Using survey data drawn from Kenyan women residing in the United States, this study aimed to answer two research questions: (1) Does membership in social media groups comprised of Kenyan female immigrants vary (e.g. by age, immigration status)? (2) Do age and immigration/citizenship status influence Kenyan female immigrants' reasons for joining social media groups? The bivariate results show that older women and those who migrated to the United States for school or through the Green Card lottery programme were likelier to join Tumaini and other immigrant‐specific social media groups. Regarding factors influencing their reasons for joining these groups, the regression results revealed that US citizens and permanent residents were less likely to join the group for solidarity/support. Furthermore, those who migrated for school or to join family members were likelier to join the Tumaini group for support/solidarity. This finding suggests that older women, being more likely to belong to physical social groups, have a relatively stronger attachment to such groups. Consequently, their willingness to join the Tumaini group, despite it being an online community, may be stronger than that of their younger counterparts.
Microstructure and mechanical properties of 3D‐printed zirconia bone scaffold: Experimental and computational analysis
Authors: Barui Srimanta , Lebert Austin , Jauregui Francisco , Munjuluri Krishna Sai Aparna , Kate Kunal 
Published: October 2024

AbstractMicroextrusion‐based additive manufacturing of zirconia‐based bioceramics is capable of fabricating design‐specific architectures with high mechanical strength properties and relative density. We developed a novel organic residue‐free binder system for zirconia paste printing (ZP2) with the shear‐thinning properties apropos to microextrusion‐based 3D printing. Based on thermogravimetric analysis, debinding protocol was established followed by high‐temperature heat treatment under four sintering conditions. Quantitative linear shrinkage (32.3%–42.7% ranging from in‐plane to vertical direction), density (83.3%–87.5%), and surface roughness (7.7–13.8 µm from the parallel to the perpendicular to the infill direction) as a factor of sintering conditions (1400°C–1500°C for 3–4 h) were analyzed. Whereas qualitative phase assemblage demonstrated “sintering condition independent” phase stability; grain growth and reduction in porosity were observed in the microstructure with increment in sintering temperature and hold time. Interestingly, at higher temperature and hold time, the compressive (46–72.4 MPa) and tensile strength (16.2–23.1 MPa) properties experienced a trade‐off between grain growth and reduction in porosity. The ZP2 scaffolds sintered at lower temperature and hold time qualified for the bone scaffold applications having interconnected porosities, biologically relevant surface roughness, and human bone mimicking mechanical properties. With a unique finite element analysis recipe, the mechanical behavior of the “life‐like” reconstructed computer aided design (CAD) geometries identical to real 3D‐printed‐sintered ZP2 scaffolds was quantitatively predicted.
What is the State of Organisational Compassion‐Based Interventions Targeting to Improve Health Professionals' Well‐Being? Results of a Systematic Review
Authors: Nielsen Camilla Littau , Lindhardt Christina Louise , Näslund‐Koch Lui , Frandsen Tove Faber , Clemensen Jane , Timmermann Connie 
Published: October 2024

ABSTRACTAimTo identify and assess the state of knowledge regarding compassion‐based interventions and outcomes, targeted to the organisational level, that aim to improve health professionals' well‐being.DesignSystematic review.Data SourcesUsing the PICO model, the clinical question and search strategy were structured. The searches were performed on 20 September 2022 and 26 December 2023 in the Scopus, CINAHL, EMBASE, PsycINFO and ProQuest Dissertations & Theses Global databases. Content analysis was applied to analyse data, and the PRISMA and SWiM guidelines were followed for reporting.ResultsThirty‐eight studies, mostly from the United Kingdom and the United States, met the inclusion criteria and were quality assessed and analysed. Compassion‐based interventions that target the organisational level are quite new, thus representing a burgeoning initiative. In this review, many included quantitative studies revealed significant methodological challenges in effectively measuring organisational compassion (interpersonal relationships, organisational culture and retention/turnover). However, the review findings overall indicate that interpersonal connections between colleagues that foster a sense of community, through shared experiences, mindfulness and (self‐)compassion practices and social activities, may be a protective factor for well‐being. Further, the review emphasises the crucial role of management support in catalysing organisational changes to improve health professionals' well‐being.ConclusionEvidence strongly suggests that fostering human interconnectedness among health professionals is associated with enhanced well‐being. Further rigorous studies are needed to validate these findings, clarify the organisational cultural aspects of compassion and develop an effective outcome measurement tool for organisational compassion.Practice ImplicationsOrganisational compassion‐based interventions may help foster a culture of compassion within organisations, enhance health professionals' capacity for compassion and benefit both their well‐being and the quality of care provided to patients and relatives.Patient ContributionsThis review is part of a larger project about compassion and includes two patient representatives (mothers of children with cancer) in the research team.
‘Balancing Challenges and Personal Resources’: A Qualitative Study of Women's Experiences of Arm Impairment After Axillary Surgery for Breast Cancer
Authors: Appelgren Matilda , Wengström Yvonne , de Boniface Jana , Sackey Helena 
Published: October 2024

ABSTRACTAimTo explore how women previously treated for breast cancer experience living with arm impairment after axillary surgery.DesignDescriptive qualitative study. The inductive starting point for the analysis was followed by a deductive approach as the categories were related to the components of the sense of coherence framework.MethodsTwenty‐eight relapse‐free Swedish‐speaking females participated in six focus group discussions conducted between September and December 2022. All participants had undergone sentinel lymph node biopsy with or without completion axillary dissection 4 years earlier. Data were analysed using qualitative content analysis.ResultsThree categories and an overall theme were identified. The categories ‘Sense‐making’, ‘Daily life’ and ‘Driving force’ reflect actions to understand and prevent arm symptoms, adaptations made in daily life and the empowering resources adopted to meet challenges. The overall theme, ‘Balancing challenges and personal resources’, comprised a process that began at diagnosis and remained ongoing for some participants. Most participants considered their new life situations manageable. However, those with more pronounced arm impairment reported that they did not always receive adequate aid, and that their daily lives were negatively affected.ConclusionReturning to everyday life after axillary surgery for breast cancer is associated with varying degrees of challenges. Individuals with persistent arm impairment find returning to normal life more challenging. Therefore, further improvements in person‐centred care are of utmost importance.Patient and Public ContributionMembers of the Swedish Breast Cancer Association were involved in the creation of the interview guide.ImpactThis study emphasises the requirement for providing further individualised support to those living with more severe arm impairment after axillary surgery.Reporting MethodThis study was reported in accordance with the Standards for Reporting Qualitative Research.
Understanding Older Persons' Experiences of Care Encounters in the Home Environment: A Hermeneutic Study
Authors: Larsson Gerdin Anna , Rönngren Ylva , Hellzén Ove , Kjällman Alm Annika , Holmström Rising Malin 
Published: October 2024

ABSTRACTAimTo explore and gain a deeper understanding of older persons' experiences of care encounters when their home becomes a workplace.BackgroundWorldwide healthcare services are increasingly being provided in older persons' homes by registered nurses. This presents new challenges as the home environment of older persons now doubles as a workplace for healthcare professionals. However, there is limited research available on how older persons experience care encounters when their homes serve as workplaces and how this influences their overall well‐being and quality of life.DesignA qualitative hermeneutic study.MethodsIn‐depth face‐to‐face interviews were conducted in Sweden from October 2023 to January 2024 with 10 purposefully selected older persons (aged 65+). Each participant received regular visits from a home care nurse in their home to address specific care needs, such as wound care, medication administration, blood sampling and general supervision. The interviews were audiotaped, transcribed verbatim and analysed using a hermeneutic interpretation.FindingsThe hermeneutic analysis emerged with one main theme: ‘Experiencing care encounters at home as a lottery’, with two underlying themes: ‘Adapting to loss of control in the private sphere’ and ‘Striving for independence while navigating daily living’.ConclusionsOlder persons try to control their lives despite the challenges associated with ageing and receiving care at home. They strive to maintain their independence and autonomy, which reflects their desire for self‐determination. Supporting these efforts in an interdependent relationship can enhance their well‐being and quality of life.Reporting MethodFindings were reported following the Consolidated Criteria for Reporting Qualitative Research guidelines.Patient or Public ContributionData were collected by patient interviews.Implications for the Profession and Patient CareThis study emphasises the importance of supporting older persons in maintaining control over their lives while being cared for in their homes. In the care encounters with home care nurses, their well‐being and quality of life can be improved by respecting their autonomy, involving them in decision‐making and offering tailored support.
Effects of multicultural experiences on empathy: A model of the roles of positive emotion and critical thinking
Authors: Zhao Nalin , Zhao Yufang , Bao Yan , Mo Xuemin , Ma Xingyang 
Published: October 2024

AbstractThe extant empirical evidence indicates that multicultural experiences (MCEs) are linked to numerous positive outcomes, including increased trust, reduced intergroup bias, and the promotion of large‐scale cooperation. These beneficial effects partly depend on the fact that increased MCEs enhance cultural sensitivity, which may enable individuals to better empathize with others. Therefore, we explored the beneficial effects of MCEs on empathy, along with the potential mechanisms. A sample of 1480 Chinese young adults (M = 21.40, SD = 1.86) were employed to complete anonymous questionnaires on their MCEs, positive emotions, critical thinking, empathy, and multicultural breadth. By controlling for gender and family socioeconomic status, parallel mediation analysis revealed that MCEs can independently influence individuals' levels of empathy through both positive emotions and critical thinking. Thereafter, multicultural breadth was determined as a moderator influencing this model. The results highlighted the role of MCEs in increasing empathy through their relationship with cognitive and emotional processes. This study is significant in expanding our understanding of the consequences of MCEs and has practical value in promoting more interpersonal harmony and social tolerance through enhanced empathy.
Influence of Natural Dentin Biomodification Agent on Push‐Out Bond Strength and Nanoleakage of Self‐Adhesive Resin Cement Luting of Glass‐Fiber Posts
Authors: Maia Italo Hudson Tavares , Rifane Tainah Oliveira , de Freitas Bárbara de Fátima Barbosa , Feitosa Victor Pinheiro , Lomonaco Diego , De Paula Diego Martins 
Published: October 2024

ABSTRACTObjectiveTo evaluate the plant‐derived compound lignin (LIG) as a pretreatment of intraradicular dentin in combination with EDTA on push‐out bond strength (PBS) and nanoleakage of the glass fiber posts (GFPs) cemented using adhesive resin cement.Material and MethodsTwenty‐eight human incisor roots were prepared for GFP cementation and divided based on dentin pretreatment: (1) CONTROL: no pretreatment, (2) EDTA: 17% EDTA for 3 min, (3) EDTA‐LIG: 17% EDTA and 2% lignin for 3 min, (4) EDTA‐PAC: 17% EDTA and 2% lignin for 3 min. The GFPs were cemented using the self‐adhesive resin cement Multilink Speed. The roots (n = 7) were sectioned into 1 mm‐thick discs and subjected to PBS testing after 1 week or 6 months. Nanoleakage was analyzed by SEM. Statistical analysis was performed using two‐factor ANOVA and Tukey's test (p < 0.05).ResultsHigher PBS was identified for the CONTROL group (p < 0.001). After 6 months, the EDTA‐LIG maintained the bond strength with a predominance of mixed failures, while the EDTA‐PAC, EDTA, and CONTROL groups showed reduction of bond strength, with a predominance of adhesive failures along with severe silver infiltration in the interface.ConclusionLIG associated with EDTA as a pretreatment for intraradicular dentin shows significant potential for attaining stable bond strength and interfacial integrity of self‐adhesive resin cement to intraradicular dentin.