bluuebunny/crossref_metadata_2025_split huggingface dataset:
SuFEx‐based Transparent Polysulfates and their Applications in Tunable Resistant Electrical Memory Materials
Authors: Zhou Feng , Liang Huizhen , Liu Tingchang , Liu Ting , Luo Wancheng , He Zhihao , Zhang Qijian 
Published: October 2024

AbstractVisibly transparent electron devices are current research highlights, which are found at the “neotype” stage of technical development for the usage in the next generation “see‐through” electronic devices. However, less attention is paid to transparent semiconductor memory devices, and hence, achieving such “see‐through” electronic devices are still partially limited by lacking the easily achievable and cost‐effective transparent memory materials. Herein, three visible light transparent polysulfate‐based memory devices are reported, e.g. ITO/P‐BPS/Al, ITO/P‐TPA/Al, and ITO/P‐TPABPS/Al, that displayed DRAM, WORM, and FLASH effects, respectively. The mechanisms of the observed memory behavior of each memory material are proposed on the basis of computational simulation. Remarkably, these polysulfates‐based memory materials are obtained by simply using different main‐chain repeating units, suggesting a wide application potential of polysulfate as functionalized materials.
Boosting Electrocatalytic Performance of Sulfide Oxidation on Polyoxomolybdates with Synergistic Effects of CNT‐Doped Aerogel Foams
Authors: Dong Chuanheng , Liu Xiaona , Li Zhen , Guo Kaihui , Song Chunman , Zhang Yalin , Zhang Meiyu , Ma Fenfen , Rosei Federico , Zhang Xianxi , Huang Xianqiang 
Published: October 2024

AbstractThe meticulous design of highly efficient indirect electrocatalysts with value‐added conversion properties remains a substantial challenge within the realm of organic catalysis. While polyoxometalates (POMs) serve as crucial active centers in catalytic modeling systems for chemical materials, their exploration in electrocatalytic organic molecular transformations is hindered by kinetic barriers. Therefore, an efficient protocol is established for the synthesis of electrocatalysts utilizing polyoxomolybdates (CuMo6) immobilized on aerogel foams (CMC). The electrical conductivity and electrocatalytic activities of the electrocatalyst (CuMo6/CNT@CMC) can be readily enhanced by adjusting the microenvironment between the CuMo6 and CMC using carbon nanotubes (CNT). Controlled experiments demonstrate that the CuMo6/CNT@CMC electrocatalyst for the oxidation of sulfide achieves an impressive Faradaic Efficiency (FE) exceeding 95% under ambient conditions, while the working potential is markedly lower than that of reported heterogeneous electrocatalysts. Combined experimental and theoretical analyses suggest that the modulated electronic synergistic interaction between the Cu‐assisted Mo sites and CNT within foam favors the appropriate binding of PhCH3S+• intermediates, thereby promoting the selective oxidation of sulfides. This study paves the way for the utilization of polyoxometalate‐based materials with simple synthesis methods for various electrocatalytic applications.
Microgels With Electrostatically Controlled Molecular Affinity to Direct Morphogenesis
Authors: Kühn Sebastian , Magno Valentina , Zimmermann Ralf , Limasale Yanuar Dwi Putra , Atallah Passant , Stoppa Aukha , Männel Max J. , Thiele Julian , Friedrichs Jens , Freudenberg Uwe , Werner Carsten 
Published: October 2024

AbstractConcentration gradients of soluble signaling molecules—morphogens—determine the cellular organization in tissue development. Morphogen‐releasing microgels have shown potential to recapitulate this principle in engineered tissue constructs, however, with limited control over the molecular cues in space and time. Inspired by the functionality of sulfated glycosaminoglycans (sGAGs) in morphogen signaling in vivo, a library of sGAG‐based microgels is developed and designated as µGel Units to Instruct Development (µGUIDEs). Adjustment of the microgel's sGAG sulfation patterns and concentration enabled the programming of electrostatic affinities that control the release of morphogens. Based on computational analyses of molecular transport processes, µGUIDEs provided unprecedented precision in the spatiotemporal modulation of vascular endothelial growth factor (VEGF) gradients in a microgel‐in‐gel vasculogenesis model and kidney organoid cultures. The versatile approach offers new options for creating morphogen signaling centers to advance the understanding of tissue and organ development.
Effect of Chlorine Inclusion in Wide Band Gap FAPbBr3 Perovskites
Authors: Ory Daniel , Ammirati Giuseppe , Paci Barbara , Baranek Philippe , Generosi Amanda , Fournier Olivier , Turchini Stefano , Toschi Francesco , Guillemoles Jean‐François , Barichello Jessica , Matteocci Fabio , Carlo Aldo Di , Milotti Valeria , Sheverdyaeva Polina M. , Moras Paolo , Catone Daniele , Cacovich Stefania 
Published: October 2024

AbstractWide bandgap perovskites have recently gained attention owing to their physical properties, versatility, and potential in various optoelectronic devices including LEDs, detectors, and building‐integrated photovoltaics (BIPV). However, BIPV materials must meet conflicting requirements, necessitating high performance, high transparency in the visible spectrum and color neutrality. This study investigates the controlled addition of chlorine in FAPb(Br1‐xClx)3 perovskites to achieve band gaps exceeding 2.4 eV. Increasing chlorine content from xCl = 0.00 to xCl = 0.25 widens the band gap from 2.37 to 2.52 eV, effectively improving the visible light transparency. Advanced characterization techniques including X‐ray diffraction, synchrotron radiation photoelectron spectroscopy, photoluminescence imaging, and fast transient absorption spectroscopy, complemented by density functional theory, reveal insights into absorption properties, electronic structure, and ultrafast recombination dynamics as a function of the thin film chemical composition. Furthermore, this study evaluates energetic disorder, carrier recombination rates, and non‐radiative losses for different compositions by extracting quantitative parameters such as Urbach energy and quasi‐Fermi level splitting, offering novel insights and guidelines for the design and optimization of emerging photovoltaic (PV) materials. Optimal PV performance metrics are achieved with a wide bandgap bromine perovskite containing 14% chlorine, striking a balance between morphology, transparency, and voltage losses.
3D Multiview Holographic Display with Wide Field of View Based on Metasurface
Authors: Xiong Haoran , Zhang Xue , Li Peijin , Zhao Ruizhe , Li Xin , Geng Guangzhou , Li Junjie , Wang Yongtian , Huang Lingling 
Published: October 2024

Abstract3D display technology offers a more realistic visual experience by allowing users to perceive depth and spatial awareness, enhancing interactivity and immersion. Among various approaches, multiview display technology constructs 3D images by offering multiple smooth views along the horizontal plane. Metasurfaces, with ultra‐thin physical structures and flexible functional designs, are positioned to make significant contributions to the evolution of 3D display technologies. Here, a 3D multiview holographic display system based on metasurfaces is proposed. Using generalized Snell's law, a spatially multiplexed metasurface is designed with nine views and achieves 3D display by cascading the metasurface with a spatial light modulator (SLM). By projecting holograms onto different areas of the metasurface via the SLM, corresponding reconstructed images can be observed from specific designed directions. Thanks to the large numerical aperture (NA) of the metasurface, the system successfully achieves nine views within a 120° field of view (FOV, with a theoretical maximum of 180°), validated experimentally. This system promises potential applications in VR/AR display, surgical navigation, geographic information system (GIS), and other fields.
Selective Preparation of Pyrrolo[2,3‐c]tetrahydroquinolines and Indolo[3,2‐c]tetrahydroquinolines through N‐Arylation/Cycloaddition/Rearrangement Annulation Reactions of Alkynyl‐Tethered Oximes with Diaryliodonium Salts
Authors: Nie Chang‐Rui , Pan Mei‐Mei , Deng Rong , Zhong Xin‐Xian , Chen Chun‐Hua , Mo Dong‐Liang 
Published: October 2024

AbstractWe describe a selective preparation of a variety of functionalized pyrrolo[2,3‐c]tetrahydroquinolines and indolo[3,2‐c]tetrahydroquinolines in 40–82% and 40–80% yields from alkynyl‐tethered oximes with diaryliodonium triflates, respectively. The one‐pot reaction underwent N‐arylation, intramolecular [3+2] cycloaddition, selective [1.3] or [3,3]‐rearrangement of N−O bond in total three steps. Experimental studies revealed that EtOAc solvent and copper(II)‐catalyst played crucial roles on the formation of these two tetrahydroquinoline scaffolds. Moreover, these two tetrahydroquinoline scaffolds could be converted into various tetrahydroquinoline building blocks by further transformations.
Regional Stiffness and Hardening Indices: New Indicators Derived from Multidimensional Dynamic CTA for Aneurysm Risk Assessment
Authors: Huang Tianming , Qi Xiaoyu , Cao Lan , Yang Ming , Luo Huan , Li Qin , Qian Peidong , Lu Jia , Lei Ziqiao , Luo Yuanming , Yang Chao 
Published: October 2024

AbstractTwo indices, indicating the regional average stiffness and the pace of strain hardening respectively, are derived from the nonlinear stress–strain behavior obtained from biomechanical analysis of aneurysm. A comprehensive method based on electrocardiographic‐gated multidimensional dynamic computed tomography angiography (MD CTA) is developed for extracting these mechanical characteristics in vivo. The proposed indices are evaluated by 26 cases including 9 healthy, one aortosclerosis, and 16 abdominal aortic aneurysm cases. The difference of SSI and dSSI value between aneurysmal and healthy groups is up to orders in magnitude. Significant correlation of these indices with the clinical indicator of aneurysm diameter is found. Logistic models based on these indices are capable to sharply discriminate the healthy and the aneurysmal arteries with AUC>0.98. This work introduces new tools and new indices for aortic mechanical assessment which may shed light on understanding the mechanical condition, pathological state and eventually benefit clinical decision‐making.
Super‐Enhancer‐Driven IRF2BP2 is Activated by Master Transcription Factors and Sustains T‐ALL Cell Growth and Survival
Authors: Yu Juanjuan , Zhang Zimu , Chen Yanling , Wang Jianwei , Li Gen , Tao Yanfang , Zhang Yongping , Yang Yang , Zhang Chenyue , Li Tiandan , Cheng Jia , Ji Tongtign , Wei Zhongling , Wang Wenjuan , Fang Fang , Jiang Wei , Chu Peipei , Yin Hongli , Wu Di , Li Xiaolu , Wang Xiaodong , Fan Jun‐Jie , Hu Shaoyan , Zhu Zhen‐Hong , Wu Shuiyan , Lu Jun , Pan Jian 
Published: October 2024

AbstractSuper enhancers (SEs) are large clusters of transcriptional enhancers driving the expression of genes crucial for defining cell identity. In cancer, tumor‐specific SEs activate key oncogenes, leading to tumorigenesis. Identifying SE‐driven oncogenes in tumors and understanding their functional mechanisms is of significant importance. In this study, a previously unreported SE region is identified in T‐cell acute lymphoblastic leukemia (T‐ALL) patient samples and cell lines. This SE activates the expression of interferon regulatory factor 2 binding protein 2 (IRF2BP2) and is regulated by T‐ALL master transcription factors (TFs) such as ETS transcription factor ERG (ERG), E74 like ETS transcription factor 1 (ELF1), and ETS proto‐oncogene 1, transcription factor (ETS1). Hematopoietic system‐specific IRF2BP2 conditional knockout mice is generated and showed that IRF2BP2 has minimal impact on normal T cell development. However, in vitro and in vivo experiments demonstrated that IRF2BP2 is crucial for T‐ALL cell growth and survival. Loss of IRF2BP2 affects the MYC and E2F pathways in T‐ALL cells. Cleavage under targets and tagmentation (CUT&Tag) assays and immunoprecipitation revealed that IRF2BP2 cooperates with the master TFs of T‐ALL cells, targeting the enhancer of the T‐ALL susceptibility gene recombination activating 1 (RAG1) and modulating its expression. These findings provide new insights into the regulatory network within T‐ALL cells, identifying potential new targets for therapeutic intervention.
Gene Therapy for Inflammatory Cascade in Intrauterine Injury with Engineered Extracellular Vesicles Hybrid Snail Mucus‐enhanced Adhesive Hydrogels
Authors: Peng Xiaotong , Wang Tao , Dai Bo , Zhu Yiping , Ji Mei , Yang Pusheng , Zhang Jiaxin , Liu Wenwen , Miao Yaxin , Liu Yonghang , Wang Shuo , Sun Jing 
Published: October 2024

AbstractEarly hyper‐inflammation caused by intrauterine injury triggered subsequent intrauterine adhesion (IUA). STAT1‐mediated M1 macrophages are confirmed to secrete pro‐inflammatory cytokines to accelerate inflammatory cascade and IUA formation by multi‐omics analysis and experimental verification. However, clinically used hyaluronic acid (HA) hydrogels are prone to slip out of injury sites due to poor bio‐adhesion properties. Therefore, there are still challenges in applying hydrogels for M1 macrophage intervention in IUA treatment. Herein, an engineered extracellular vesicles (EVs) hybrid snail mucus (SM)‐enhanced adhesive hydrogels to improve bio‐adhesion property is fabricated and M1 macrophage intervention through targeting delivery and STAT1 silencing is achieved. First, inspired by the high bio‐adhesion capacity of SM, SM and gelatin methacrylate (GelMA) solution are mixed to construct GelMA/SM (GS) hydrogel. Then, folic acid‐modified extracellular vesicles (FA‐EVs) are synthesized for targeting the delivery of STAT1‐siRNA. Upon injection of FA‐EVs hybrid GS hydrogel into the uterine cavity, a protective hydrogel layer forms on the surface of injury sites and sustains the release of STAT1‐siRNA‐loaded FA‐EVs to curtail M1 macrophages generation through inhibiting STAT1 phosphorylation, resulting in reduction of myofibroblasts activation and collagen deposition. In addition, the pregnancy rate and the number of fetuses in rats treated with this hydrogel were much higher than those in other groups, suggesting that the hydrogel could promote functional endometrial regeneration and restore fertility. Overall, this study presents a promising strategy for employing FA‐EVs hybrid adhesive hydrogel with superior bio‐adhesion properties and M1 macrophage targeting delivery for IUA treatment and uterus recovery.
Confining Flat Ru Islands into TiO2 Lattice with the Coexisting Ru–O–Ti and Ru–Ti Bonds for Ultra‐Stable Hydrogen Evolution at Amperometric Current Density and Hydrogen Oxidation at High Potential
Authors: Chen Luyun , Li Chunlei , Liu Mengling , Dai Ziruo , Wang Haibin , Zhou Xuan , Zhao Qiuping , Cong Yuanyuan 
Published: October 2024

AbstractEffective hydrogen evolution reaction (HER) under high current density and enhanced hydrogen oxidation reaction (HOR) over a wide potential range remain challenges for Ru‐based electrocatalysts because its strong affinity to the adsorbed hydroxyl (OHad) inhibits the supply of the adsorbed hydrogen (Had). Herein, the coexisting Ru─O─Ti and Ru─Ti bonds are constructed by taking TiO2 crystal confined flat‐Ru clusters (F‐Ru@TiO2) to cope with above‐mentioned obstacles. The different electronegativity (χTi = 1.54 < χRu = 2.20< χO = 3.44) can endow Ti in Ru─O─Ti bonds with more positive charge and stabilize Ru of Ru–Ti bonds with the low‐valence. The strength of Ru─OHad is then weakened by the oxophilicity of positively charged Ti in Ru─O─Ti bonds and the stronger Ti─OHad bond could release active Ru, especially for low‐valence Ru in Ru─Ti bonds, to serve as exclusive Had sites. As expected, F─TiRu@TiO2 shows a low HER overpotential of 74 mV at 1000 mA cm−2 and an ultrahigh mass activity (j0,m) of 3155 A gRu−1 for HOR. More importantly, F─Ru@TiO2 can tolerate the HER current density of 1000 mA cm−2 for 100 h and the high anodic potential for HOR up to 0.5 V versus RHE.
As‐Doped Polycrystalline CdSeTe: Localized Defects, Carrier Mobility and Lifetimes, and Impact on High‐Efficiency Solar Cells
Authors: Ščajev Patrik , Nardone Marco , Reich Carey , Farshchi Rouin , McReynolds Kevin , Krasikov Dmitry , Kuciauskas Darius 
Published: October 2024

AbstractThe efficiency potential for single‐junction photovoltaics (PV) is described by the detailed balance model, which requires the elimination of nonradiative recombination and perfect minority carrier collection. Improvements in GaAs, Si, and perovskite PV follow this model. It might be more complex for CdTe, a leading thin‐film PV technology. While lifetime, passivation, and doping goals for 25% efficient CdTe solar cells are largely reached, voltage is ≈20% below the detailed balance limit. Why is that? In Se‐alloyed CdSexTe1‐x (Se is required for >20% efficiency) additional losses can occur due to electrostatic and bandgap fluctuations and due to electronic trap states. To understand mechanisms limiting CdSeTe solar cell performance and to suggest improvements, carrier dynamics, and transport in CdSexTe1‐x with variation in Se composition and as doping is analyzed. It is shown that trapping, likely due to anion‐site defects and their complexes, is correlated with low charge carrier mobility of 0.1–0.6 cm2 (Vs)−1. Even with 1000 ns charge carrier lifetimes, carrier diffusion length is less than the absorber thickness, reducing efficiency to ≈23%. Device simulations are used to analyze the performance of CdSexTe1‐x solar cells; thermodynamic models are not sufficient for absorbers with electronic disorder and trapping.
Bioassay‐Guided Extraction and Isolation of Natural Herbicides from Dried Zanthoxylum limonella Alston Fruits
Authors: Chotpatiwetchkul Warot , Charoenying Patchanee , Teerarak Montinee , Meesin Jatuporn , Jongkon Nathjanan , Chotsaeng Nawasit , Laosinwattana Chamroon 
Published: October 2024

AbstractWeeds are problematic plant species around the world. Various strategies exist for controlling weeds, but chemical treatment remains the preferred method, particularly when using natural substances. In this research, a crude aqueous‐methanol extract from dried Zanthoxylum limonella fruits was acid‐base partitioned into four fractions: neutral extract (NE), acid extract (AE), basic extract (BE), and aqueous extract (AQ). These fractions were further separated into seventeen subfractions: NEF1 to NEF7, AEF1 to AEF5, and BEF1 to BEF5, which were then tested for herbicidal activity against the growth of Chinese amaranth (Amaranthus tricolor) and barnyard grass (Echinochloa crus‐galli). Active subfractions were isolated via column chromatography and identified using spectroscopic methods, yielding seven active compounds: xanthoxyline (1), tambulin (2), atanine (3), prudomestin (4), skimmianine (5), p‐methoxybenzoic acid (6), and methyl caffeate (7). Compounds 2–7 had not been previously reported in Z. limonella. Xanthoxyline (1) was identified as the most potent botanical herbicide, fully inhibiting seed germination of Chinese amaranth and barnyard grass. This compound also decreased seed imbibition and α‐amylase activity in both species. Molecular docking studies on the α‐amylase enzyme (PDB ID: 1BG9) revealed that the aromatic, hydroxy, and carbonyl groups of xanthoxyline (1) interact with the enzyme's active sites.
Lebendzell‐Identifizierung von Inhibitoren des Lipid‐Transfer Proteins CERT Mithilfe von Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET)
Authors: Kirmpaki Maria‐Anna , Saied Essa M. , Schumacher Fabian , Prause Kevin , Kleuser Burkhard , Arenz Christoph 
Published: October 2024

AbstractEs wird ein BRET‐System beschrieben, für das Nanoluciferase mit dem Lipidtransferprotein CERT fusioniert wurde. Dadurch wird ein effizienter Energietransfer auf ein mit Nilrot markiertes Ceramid ermöglicht, das entweder direkt an CERT gebunden oder zur benachbarten Golgi‐Membran transportiert wird. Der CERT‐vermittelte Transfer des Intermediats Ceramid ist Voraussetzung für die Bildung von Sphingomyelin, einer wichtigen Plasmamembrankomponente bei Säugetieren. CERT gilt als vielversprechende Zielstruktur für Medikamente, jedoch gibt es keine direkten zellbasierten Methoden zur effizienten Identifizierung von Inhibitoren. Der Nutzen der hier entwickelten Methode wurde anhand einer Bibliothek von 140 Derivaten des CERT‐Inhibitors HPA‐12 demonstriert. Diese wurden in einer kombinatorischen Synthese mittels Festphasen‐Transacylierung gewonnen. Das Screening der Bibliothek führte zur Identifizierung von sechs Verbindungen, die in einer Dosis‐Wirkungs‐Studie sowie in einer orthogonalen Lipidomics‐Analyse als dem HPA‐12 überlegen bestätigt wurden.
Robust and Reversible Thermal/Electro‐Responsive Supramolecular Polymeric Adhesives via Synergistic Hydrogen‐Bonds and Ionic Junctions
Authors: Deng Qizhe , Han Shengli , Wu Yanggui , Chen Yiwen , Zhang Yinhua , Zhao Yonggang , Chen Senbin , Zhu Jintao 
Published: October 2024

AbstractAdhesive conducting elastomers are rising materials towards cutting‐edge applications in wearable and implantable soft electronics. Yet, engineering the conductive adhesives with robust and tunable interfacial bonding strength is still in its infancy stage. We herein identify a structurally novel supramolecular polymer scaffold, characterized by synergistic coexistence of hydrogen‐bonding (H−bonding) interactions and electrostatic ionic junctions, endowing the robust and tunable elastic conducting adhesives with remarkable thermal/electro‐responsive performance. H−bonding association and electrostatic interaction play orthogonal yet synergistic roles in the strong supramolecular adhesive formation, serving as the leveraging forces for opposing both cohesion and adhesion energy. To do so, six‐arm star‐shaped random copolymers P1, and P2 are strategically designed, bearing H−bonding PDAP (poly(diaminopyridine acrylamide)) and PThy (poly(thymine)) segments, which can form hetero‐complementary DAP/Thy H−bonding association, along with ionic conductive poly(ionic liquid)s segment: PMBT, (poly(1‐[2‐methacryloylethyl]‐3‐methylimidazolium bis(trifluoromethane)‐sulfonamide)). DAP/Thy H−bonding association, along with electrostatic ionic interaction, can yield dual supramolecular forces crosslinked polymeric networks with robust cohesion energy. Moreover, coexistence of poly(ionic liquid)s can impact and interfere the configuration of H−bonding association, liberate more free DAP and Thy motifs to form H−bonds towards substrate, affording strong surface adhesion in a synergistic manner. This work demonstrates a significant forward step towards potential adhesives devoted to hybrid electronic devices.