bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential use of cowpea (Vigna unguiculata (L.) Walp.) stover treated with white‐rot fungi as rabbit feed
Authors: Andrade Ederson , Pinheiro Victor , Gonçalves Alexandre , Cone John W , Marques Guilhermina , Silva Valéria , Ferreira Luis , Rodrigues Miguel 
Published: April 2017

AbstractBACKGROUNDLignin inhibitory effects within the cell wall structure constitute a serious drawback in maximizing the utilization of fibrous feedstuffs in animal feeding. Therefore treatments that promote efficient delignification of these materials must be applied. This study evaluated the potential of white‐rot fungi to upgrade the nutritive value of cowpea stover for rabbit feeding.RESULTSThere was an increase in the crude protein content of all substrates as a result of fungi treatments, reaching a net gain of 13% for Pleurotus citrinopileatus incubation. Overall, net losses of dry and organic matter occurred during fungi treatments. Although the fiber content remained identical, higher consumption of cell wall contents was measured for P. citrinopileatus incubation (between 40 and 45%). The incubation period did not influence lignin degradation for any of the fungi treatments. Differences within the fungal degradation mechanisms indicate that P. citrinopileatus treatment was most effective, enhancing in vitro organic matter digestibility by around 30% compared with the control.CONCLUSIONTreatment of cowpea stover with P. citrinopileatus led to an efficient delignification process which resulted in higher in vitro organic matter digestibility, showing its potential in the nutritional valorization of this feedstuff. © 2017 Society of Chemical Industry
Retrospective single center study of the efficacy of large spot 532 nm laser for the treatment of facial capillary malformations in 44 patients with the use of three‐dimensional image analysis
Authors: Kwiek Bartłomiej , Rożalski Michał , Kowalewski Cezary , Ambroziak Marcin 
Published: April 2017

ObjectiveWe wanted to asses the efficacy of large spot 532 nm laser for the treatment of facial capillary malformations with the use of three‐dimensional (3D) image analysis.Study Design and MethodsRetrospective single center study on previously non‐treated patients with facial capillary malformations (CM) was performed. A total of 44 consecutive Caucasian patients aged 5–66 were included. Patients had 3D photography performed before and after and had at least one single session of treatment with 532 nm neodymium‐doped yttrium aluminum garnet (Nd:YAG) laser with contact cooling, fluencies ranging from 8 to 11.5 J/cm2, pulse duration ranging from 5 to 9 milliseconds and spot size ranging from 5 to 10 mm. Objective analysis of percentage improvement based on 3D digital assessment of combined color and area improvement (global clearance effect [GCE]) were performed.ResultsMedian maximal improvement achieved during the treatment (GCEmax) was 70.4%. Mean number of laser procedures required to achieve this improvement was 7.1 (ranging from 2 to 14)). Improvement of minimum 25% (GCE 25) was achieved by all patients, of minimum 50% (GCE 50) by 77.3%, of minimum 75% (GCE 75) by 38.6%, and of minimum 90% (GCE 90) by 13.64.ConclusionLarge spot 532 nm laser is highly effective in the treatment of facial CM. 3D color and area image analysis provides an objective method to compare different methods of facial CM treatment in future studies. Lasers Surg. Med. 49:743–749, 2017. © 2017 Wiley Periodicals, Inc.
Quantitative contrast‐enhanced spectral mammography based on photon‐counting detectors: A feasibility study
Authors: Ding Huanjun , Molloi Sabee 
Published: April 2017

PurposeTo investigate the feasibility of accurate quantification of iodine mass thickness in contrast‐enhanced spectral mammography.Materials and methodsA computer simulation model was developed to evaluate the performance of a photon‐counting spectral mammography system in the application of contrast‐enhanced spectral mammography. A figure‐of‐merit (FOM), which was defined as the decomposed iodine signal‐to‐noise ratio (SNR) with respect to the square root of the mean glandular dose (MGD), was chosen to optimize the imaging parameters, in terms of beam energy, splitting energy, and prefiltrations for breasts of various thicknesses and densities. Experimental phantom studies were also performed using a beam energy of 40 kVp and a splitting energy of 34 keV with 3 mm Al prefiltration. A two‐step calibration method was investigated to quantify the iodine mass thickness, and was validated using phantoms composed of a mixture of glandular and adipose materials, for various breast thicknesses and densities. Finally, the traditional dual‐energy log‐weighted subtraction method was also studied as a comparison. The measured iodine signal from both methods was compared to the known value to characterize the quantification accuracy and precision.ResultsThe optimal imaging parameters, which lead to the highest FOM, were found at a beam energy between 42 and 46 kVp with a splitting energy at 34 keV. The optimal tube voltage decreased as the breast thickness or the Al prefiltration increased. The proposed quantification method was able to measure iodine mass thickness on phantoms of various thicknesses and densities with high accuracy. The root‐mean‐square (RMS) error for cm‐scale lesion phantoms was estimated to be 0.20 mg/cm2. The precision of the technique, characterized by the standard deviation of the measurements, was estimated to be 0.18 mg/cm2. The traditional weighted subtraction method also predicted a linear correlation between the measured signal and the known iodine mass thickness. However, the correlation slope and offset values were strongly dependent on the total breast thickness and density.ConclusionThe results of this study suggest that iodine mass thickness for cm‐scale lesions can be accurately quantified with contrast‐enhanced spectral mammography. The quantitative information can potentially improve the differential power for malignancy.
Changes in microstructure of two ammonium‐based protic ionic liquids proved by in situ variable‐temperature 1H NMR spectroscopy: influence of anion
Authors: Tang Xiaochen , Xu Yingjie , Zhu Xiao , Lu Yueqing 
Published: April 2017

In this work, changes in microstructure of two protic ionic liquids (PILs), namely n‐butylammonium acetate (N4Ac) and n‐butylammonium nitrate (N4NO3), are proved by in situ variable‐temperature 1H NMR spectroscopy at the temperature range from 25 to 115 °C, and the influence of the nature of anion is discussed accordingly. The results demonstrate that 1H NMR chemical shifts of alkyl protons of both N4Ac and N4NO3 are almost not changed with the increasing of temperature, due to the absence of hydrogen bond interaction between alkyl protons with anions. Whereas those of +N―H of cation decrease linearly with the temperature increasing, indicating that the hydrogen bond interaction between +N―H and anion weakens gradually. In addition, the strength of hydrogen bond interaction between +N―H and NO3− is stronger than that between +N―H and Ac−, suggesting that anions have a significant influence on microstructure due to the acidity of a Brønsted acid. Consequently, the proton transfer from cation to anion is much easier in N4Ac compared to N4NO3. Further analyses of 1H NMR chemical shifts of +N―H in N4Ac at the temperature range from 100 to 115 °C suggest that the splitting of +N―H peak may be attributed to obvious evidence of the existence of the proton transfer from +N―H to Ac−, which leads to dissociate the contact ion‐pair in N4Ac to form the neutral ion‐pair ‘molecule’. The results will help us to extensively understand the behavior of proton transfer and offer us some valuable information for the design of PILs. Copyright © 2017 John Wiley & Sons, Ltd.
Electropolymerization of hydrogen bond supramolecular associations between terthiophene‐3‐acetic acid and 4,4′‐bipyridine
Authors: Beouch Layla , Boileau Sylvie , Chevrot Claude , Tran‐Van François 
Published: April 2017

AbstractSupramolecular assemblies based on 4,4′‐bipyridine as hydrogen acceptor and a terthiophene carboxylic acid (3‐TTAA) as hydrogen donor were synthesized and characterized by Fourier transform IR spectroscopy and DSC. Their electropolymerization was successful in methylene chloride or acetonitrile. The concept of using such supramolecular assemblies in electropolymerization opens the way to the facile synthesis of new π‐conjugated polymers. © 2017 Society of Chemical Industry
Quality of death, rumination, and posttraumatic growth among bereaved family members of cancer patients in home palliative care
Authors: Hirooka Kayo , Fukahori Hiroki , Taku Kanako , Togari Taisuke , Ogawa Asao 
Published: April 2017

AbstractObjectiveThe current study was designed to test the hypothesis that quality of death (QOD) and intrusive and deliberate rumination are associated with posttraumatic growth (PTG) among bereaved family members of cancer patients in home palliative care.MethodsData were collected from 805 bereaved family members of cancer patients who died at home in Japan. We used a cross‐sectional design and participants completed Good Death Inventory, Event‐Related Rumination Inventory, and PTG Inventory. Structural equation modeling was used to test the hypothesized relationships.ResultsA direct pathway from QOD to PTG was significant. We also found significant indirect pathways between QOD and PTG via deliberate rumination soon after the death and recent deliberate rumination.ConclusionsClinicians should provide high‐quality end‐of‐life care with the goals of achieving a good death for terminally ill cancer patients and supporting the experience of PTG in bereaved family members after their loss.
Novel amino acid ester–chlorantraniliprole conjugates: design, synthesis, phloem accumulation and bioactivity
Authors: Yao Guangkai , Wen Yingjie , Zhao Chen , Xu Hanhong 
Published: April 2017

AbstractBACKGROUNDConjugating amino acid and glucose fragments with existing pesticide structures has been shown to be an effective way to introduce phloem mobility into non‐phloem mobile species. However, the resulting derivatives always suffer from lower bioactivity compared with their parent compound. To solve this problem, we designed and synthesised a series of ester‐capped amino‐acid‐conjugated chlorantraniliproles.RESULTSThe systemic test showed that all conjugates exhibited excellent phloem mobility and xylem mobility in a Ricinus communis model. In particular, compounds 7b, 8b and 8c were able to accumulate in phloem tissues in the form of their hydrolysis products, and the concentrations in phloem sap can reach 3 times the concentration in the incubation medium. Although their insecticidal activity (LC50) against the beet armyworm (Spodoptera exigua) in vitro was weaker than that of chlorantraniliprole, compounds 7b, 8b and 8c showed similar insecticidal activity in vivo against beet armyworm compared with the parent compound.CONCLUSIONSThis work provides a potential strategy to obtain pesticide derivatives that possess both improved uptake and improved mobility in crops while retaining the in vivo insecticidal effect of the parent compound. © 2017 Society of Chemical Industry
A quartic force field coordinate substitution scheme using hyperbolic sine coordinates
Authors: Alonso de Armiño Diego J. , Bustamante Carlos M. 
Published: April 2017

AbstractQuartic force fields (QFF) are currently the most cost‐effective method for the approximation of potential energy surfaces for the calculation of anharmonic vibrational energies. It is known, although, that its performance can be less than satisfactory due to limitations related to slow convergence of the series. In this article, we present a coordinate substitution scheme using a combination of Morse and sinh coordinates, well adapted for its use with cartesian normal coordinates. We derive expressions for analytical integrals for use in VSCF and VCI calculations and show that the simultaneous substitution of symmetric and antisymmetric normal coordinates by Morse and sinh coordinates, respectively, significantly improves the vibrational transition frequencies for these modes in a well‐balanced fashion. The accuracy of this substitution scheme is demonstrated by comparing one and two‐dimensional sections of substituted and unsubstituted QFF with ab initio potential energy grids, as well as with vibrational energy calculations using as test cases two well‐studied benchmark molecules: water and formaldehyde. We conclude that the coordinate substitution scheme presented constitutes a very attractive alternative to simple QFFs in the context of cartesian normal coordinates.
Playing for Real
Authors: Cantrell Tom , Luckhurst Mary 
Published: April 2017

This is the first book to explore how actors play real people. How do you capture Hitler, Mugabe, or a serial killer? How do you portray living monarchs or political leaders? Is it possible to embody a genius like Mozart, Woolf or Darwin? What are the pressures of performing an icon like Marlene Dietrich?
Bringing together original conversations with award-winning actors, the line-up includes Jeremy Irons, Dame Eileen Atkins, David Morrissey, Henry Goodman, and Sir Ian McKellen.
Understanding the Effects of Practices on KDE Ecosystem Health
Authors: da Silva Amorim Simone , McGregor John D. , de Almeida Eduardo Santana , von Flach Garcia Chavez Christina 
Published: April 2017

AbstractOpen source software ecosystems have adjusted and evolved a set of practices over the years to support the delivery of sustainable software. However, few studies have investigated the impacts of such practices on the health of these ecosystems. In this paper, we present the results of an ethnographic-based study conducted during the Latin-American KDE users and contributors meeting (LaKademy 2015) with the goal of collecting practices used within the KDE ecosystem and understanding how they affect ecosystem health. The analysis was based on softgoal interdependency graphs adapted to represent practices and relate them to non-functional requirements and goals. Our results provide a preliminary insight to understand how KDE ecosystem community interacts, which working practices have been adopted and how they affect ecosystem health.
Progression and Forecast of a Curated Web-of-Trust: A Study on the Debian Project’s Cryptographic Keyring
Authors: Wolf Gunnar , González Quiroga Víctor 
Published: April 2017

AbstractThe Debian project is one of the largest free software undertakings worldwide. It is geographically distributed, and participation in the project is done on a voluntary basis, without a single formal employee or directly funded person. As we will explain, due to the nature of the project, its authentication needs are very strict—User/password schemes are way surpassed, and centralized trust management schemes such as PKI are not compatible with its distributed and flat organization; fully decentralized schemes such as the PGP Web of Trust are insuficient by themselves. The Debian project has solved this need by using what we termed a “curated Web of Trust”.We will explain some lessons learned from a massive key migration process that was triggered in 2014. We will present the social insight we have found from examining the relationships expressed as signatures in this curated Web of Trust, some recommendations on personal key-signing policies, and a statistical study and forecast on aging, refreshment and survival of project participants stemming from an analysis on their key-handling.
Understanding When to Adopt a Library: A Case Study on ASF Projects
Authors: Ihara Akinori , Fujibayashi Daiki , Suwa Hirohiko , Kula Raula Gaikovina , Matsumoto Kenichi 
Published: April 2017

AbstractSoftware libraries are widely used by both industrial and open source client projects. Ideally, a client user of a library should adopt the latest version that the library project releases. However, sometimes the latest version is not better than a previous version. This is because the latest version may include additional developer effort to test and integrate all changed features. In this study, our main goal is to better understand the relationship between adoption of library versions and its release cycle. Specifically, we conducted an empirical study of release cycles for 23 libraries and how they were adopted by 415 Apache Software Foundation (ASF) client projects. Our findings show that software projects are quicker to update earlier rapid-release libraries compared to library projects with a longer release cycle. Moreover, results suggest that software projects are more likely to adopt the latest version of a rapid-release library compared to libraries with a longer release cycles.
OSSpal: Finding and Evaluating Open Source Software
Authors: Wasserman Anthony I. , Guo Xianzheng , McMillian Blake , Qian Kai , Wei Ming-Yu , Xu Qian 
Published: April 2017

Abstract
This paper describes the OSSpal project, which is aimed at helping companies, government agencies, and other organizations find high quality free and open source software (FOSS) that meets their needs. OSSpal is a successor to the Business Readiness Rating (BRR), combining quantitative and qualitative evaluation measures for software in various categories. Instead of a purely numeric calculated score OSSpal adds curation of high-quality FOSS projects and individual user reviews of these criteria. Unlike the BRR project, for which there was no automated support, OSSpal has an operational, publicly available website where users may search by project name or category, and enter ratings and reviews for projects.
Investigating Relationships Between FLOSS Foundations and FLOSS Projects
Authors: Lindman Juho , Hammouda Imed 
Published: April 2017

AbstractFoundations function as vital institutional support infrastructures for many of the most successful open source projects, but the role of these support entities remains an understudied phenomenon in FLOSS research. Drawing on Open Hub (formerly known as Ohloh) data, this paper empirically investigates the different ways these entities support projects and interact with different projects and with each other.
Principled Evaluation of Strengths and Weaknesses in FLOSS Communities: A Systematic Mixed Methods Maturity Model Approach
Authors: Andrade Sandro , Saraiva Filipe 
Published: April 2017

AbstractContext: Free and Open Source Software usually results from intricate socio-technical dynamics operating in a diverse and geographically dispersed community. Understanding the fundamental underpinnings of healthy and thriving communities is of paramount importance to evaluate existing efforts and identify improvement opportunities. Objective: This paper presents a novel reference model for evaluating the maturity of FLOSS communities by mixing quantitative and qualitative methods. Method: We build upon established guidelines for Design Science research in order to devise a well-informed and expressive maturity model, describing how those methods and procedures were used in the design and development of such a model. Results: We present the model structure and functions, as well as instructions on how to instantiate it as evaluations of FLOSS communities. The use of the proposed maturity model is demonstrated in four FLOSS communities. Conclusion: Whilst instantiating the model may be burdensome if aiming at sketchy evaluations, results indicate our model effectively captures the maturity regardless aspects such as community size and lifetime.
Measuring Perceived Trust in Open Source Software Communities
Authors: Syeed Mahbubul , Lindman Juho , Hammouda Imed 
Published: April 2017

AbstractWe investigate the different aspects of measuring trust in Open Source Software (OSS) communities. In the theoretical part we review seminal works related to trust in OSS development. This investigation provides background to our empirical part where we measure trust in a community (in terms of kudo). Our efforts provide further avenues to develop trust-based measurement tools. These are helpful for academics and practitioners interesting in quantifiable traits of OSS trust.
Cancer Genetic Counseling and Testing in an Era of Rapid Change
Authors: Hooker Gillian W. , Clemens Keelia Rhoads , Quillin John , Vogel Postula Kristen J. , Summerour Pia , Nagy Rebecca , Buchanan Adam H. 
Published: April 2017

AbstractThe impacts of the Association for Molecular Pathology vs. Myriad Supreme Court decision regarding patenting DNA segments and multi‐gene testing on cancer genetic counseling practice have not been well described. We aimed to assess genetic counselors’ perceptions of how their genetic testing‐related practices for hereditary breast and/or ovarian cancer (HBOC) changed after these events. One‐hundred fifty‐two genetic counselors from the National Society of Genetic Counselors Cancer Special Interest Group completed an anonymous, online, mixed‐methods survey in November 2013. The survey presented four hypothetical patients and asked about changes in testing practice. Across the vignettes, a majority of participants reported specific changes in testing decisions following Association for Molecular Pathology vs. Myriad and availability of multi‐gene testing. Ninety‐three percent of participants reported changing the types of first‐ and second‐line tests they order for HBOC; the degree of change varied geographically. Qualitative analysis indicated that some counselors have altered the counseling session content, trading depth of information for breadth and spending more time counseling about uncertainty. This study shows that cancer genetic counselors are adapting quickly to genetic testing changes, but with wide variability. Findings suggest future research to elucidate clinicians’ and patients’ preferences for guidance on the clinical implementation of next‐generation sequencing.
Chromosomal Preimplantation Genetic Diagnosis: 25 Years and Counting
Authors: Sanders Kathryn D. , Griffin Darren K. 
Published: April 2017

AbstractPreimplantation genetic diagnosis (PGD), first successfully carried out in humans in the early 1990s, initially involved the PCR sexing of embryos by Y- (and later also X-) chromosome specific detection. Because of the problems relating to misdiagnosis and contamination of this technology however the PCR based test was superseded by a FISH-based approach involving X and Y specific probes. Sexing by FISH heralded translocation screening, which was shortly followed by preimplantation genetic screening (PGS) for Aneuploidy. Aneuploidy is widely accepted to be the leading cause of implantation failure in assisted reproductive technology (ART) and a major contributor to miscarriage, especially in women of advanced maternal age. PGS (AKA PGD for aneuploidy PGD-A) has had a chequered history, with conflicting lines of evidence for and against its use. The current practice of trophectoderm biopsy followed by array CGH or next generation sequencing is gaining in popularity however as evidence for its efficacy grows. PGS has the potential to identify viable embryos that can be transferred thereby reducing the chances of traumatic failed IVF cycles, miscarriage or congenital abnormalities and facilitating the quickest time to live birth of chromosomally normal offspring. In parallel to chromosomal diagnoses, technology for PGD has allowed for improvements in accuracy and efficiency of the genetic screening of embryos for monogenic disorders. The number of genetic conditions available for screening has increased since the early days of PGD, with the human fertilization and embryology authority currently licensing 419 conditions in the UK [1]. A novel technique known as karyomapping that involves SNP chip screening and tracing inherited chromosomal haploblocks is now licensed for the PGD detection of monogenic disorders. Its potential for the universal detection of chromosomal and monogenic disorders simultaneously however, has yet to be realized.