bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of Bridged Polysilsesquioxane Membranes from Bis[3-(triethoxysilyl)propyl]amine for Water Desalination
Authors: Yamamoto Kazuki , Koge Sayako , Sasahara Kenji , Mizumo Tomonobu , Kaneko Yoshiro , Kanezashi Masakoto , Tsuru Toshinori , Ohshita Joji 
Published: June 2017

Abstract
Bridged polysilsesquioxane membranes containing amine units were prepared from bis[3-(triethoxysilyl)propyl]amine (BTESPA) by a sol-gel process, which consisted of sol formation by hydrolysis/condensation polymerization of BTESPA under neutral conditions and calcination of cast films of the sols on sulfonated polyethersulfone support membrane. A similar treatment of BTESPA, including sol formation under acidic conditions, afforded membrane with ammonium units. Thus-obtained porous BTESPA-based membrane was subjected to reverse osmosis (RO) experiments using 2000 ppm aqueous NaCl solution to examine its water desalination properties. Maximal liquid permeance (1.2 × 10−13 m3/m2·Pa·s) and NaCl rejection (97%) were achieved using the ammonium-containing membrane.
Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation
Authors: Dallaku Kastriot , Shakur Haleema , Edwards Phil , Beaumont Danielle , Roberts Ian , Huque Sumaya , Delius Maria , Mansmann Ulrich 
Published: June 2017

Background. Postpartum haemorrhage (PPH) is a potentially life-threatening complication for women, and the leading cause of maternal mortality. Tranexamic acid (TXA) is an antifibrinolytic used worldwide to treat uterine haemorrhage and to reduce blood loss in general surgery. TXA may have effects on thrombin generation, platelet function and coagulation factors as a result of its inhibition on the plasmin. Methods. WOMAN ETAPlaT is a sub-study of the World Maternal Antifibrinolitic trial (WOMAN trial). All adult women clinically diagnosed with PPH after a vaginal delivery or caesarean section, are eligible for inclusion in the study. Blood samples will be collected at the baseline and 30 minutes after the first dose of study treatment is given. Platelet function will be evaluated in whole blood immediately after sampling with Multiplate® tests (ADPtest and TRAPtest). Thrombin generation, fibrinogen, D-dimer, and coagulation factors vW, V and VIII will be analysed using platelet poor plasma. Results. Recruitment to WOMAN ETAPlaT started on 04 November 2013 and closed on 13 January 2015, during this time 188 patients were recruited. The final participant follow-up was completed on 04 March 2015. This article introduces the statistical analysis plan for the study, without reference to unblinded data. Conclusion. The data from this study will provide evidence for the effect of TXA on thrombin generation, platelet function and coagulation factors in women with PPH. Trial registration: ClinicalTrials.gov Identifier: NCT00872469; ISRCTN76912190
Thinking About Measures and Measurement in Positivist Research: A Proposal for Refocusing on Fundamentals
Authors: Burton-Jones Andrew , Lee Allen S. 
Published: June 2017

We challenge two taken-for-granted assumptions about measurement in positivist research. The first assumption is that measures and measurements are relevant for quantitative, but not qualitative, research. We explain why they apply to both types of research. The second assumption we challenge is that existing measurement practices are unproblematic, even if researchers sometimes vary in how well they enact them. We explain why current norms (both espoused and enacted) are deficient in some important ways because they fail to emphasize the fundamental issues of measures and measurements. Drawing on symbolic logic, we provide a framework to help positivist researchers to assess efforts in measuring and measurement regardless of their quantitative or qualitative orientation. The framework provides more parsimonious and broadly applicable guidance than available to date and suggests the need to refocus on measurement fundamentals. The online appendix is available at https://doi.org/10.1287/isre.2017.0704 .
Attitudes towards attrition among UK trainees in obstetrics and gynaecology
Authors: Gafson Irene , Currie Jane , O'Dwyer Sabrina , Woolf Katherine , Griffin Ann 
Published: June 2017

Physician dissatisfaction in the workplace has consequences for patient safety. Currently in the UK, 1 in 5 doctors who enter specialist training in obstetrics and gynaecology leave the programme before completion. Trainee attrition has implications for workforce planning, organization of health-care services and patient care. The authors conducted a survey of current trainees' and former trainees' views concerning attrition and ‘peri-attrition’ – a term coined to describe the trainee who has seriously considered leaving the specialty. The authors identified six key themes which describe trainees' feelings about attrition in obstetrics and gynaecology: morale and undermining; training processes and paperwork; support and supervision; work–life balance and realities of life; NHS environment; and job satisfaction. This article discusses themes of an under-resourced health service, bullying, lack of work–life balance and poor personal support.
Thermal Conductivity and the Unfrozen Water Contents of Volcanic Ash Deposits in Cold Climate Conditions: A Review
Authors: Kuznetsova Elena 
Published: June 2017

AbstractLayers of volcanic ash and Andosol soils derived from the ash may play an important role in preserving snow and ice as well as in the development of permafrost conditions in (a) the immediate vicinity of volcanoes at high elevations or at high latitudes and (b) land areas that are often distant from volcanic activity and are either prone to permafrost or covered by snow and ice, but have been affected by subaerial ash deposition. The special properties of volcanic ash are critically reviewed, particularly in relation to recent research in Kamchatka in the Far East of Russia. Of special importance are the thermal properties, the unfrozen water contents of ash layers, and the rate of volcanic glass weathering.Weathering of volcanic glass results in the development of amorphous clay minerals (e.g. allophane, opal, palagonite), but occurs at a much slower rate under cold compared to warm climate conditions. Existing data reveal (1) a strong correlation between the thermal conductivity, the water/ice content, and the mineralogy of the weathered part of the volcanic ash, (2) that an increase in the amounts of amorphous clay minerals (allophane, palagonite) increases the proportion of unfrozen water and decreases the thermal conductivity, and (3) that amorphous silica does not alter to halloysite or other clay minerals, even in the Early Pleistocene age (Kamchatka) volcanic ashes or in the Miocene and Pliocene deposits of Antarctica due to the cold temperatures. The significance of these findings are discussed in relation to past climate reconstruction and the influence of volcanic ash on permafrost aggradation and degradation, snow and ice ablation, and the development of glaciers.
Single-Nucleotide Polymorphism Leading to False Allelic Fraction by Droplet Digital PCR
Authors: Christenson Eric S , Dalton W Brian , Chu David , Waters Ian , Cravero Karen , Zabransky Daniel J , DeZern Amy E , Park Ben H o 
Published: June 2017

Abstract

BACKGROUND
Molecular-based diagnostics have great utility for cancer detection. We have used droplet digital PCR (ddPCR) as a platform for identifying mutations in circulating plasma tumor DNA (ptDNA). We present the unexpected finding of a spurious mutant allele fraction that was discovered to be artifactual because of the presence of a single-nucleotide polymorphism (SNP) in a patient sample.

DESIGN AND METHODS
Probe and primer combinations for the K700 and V701 loci of the SF3B1 spliceosome gene were designed for ddPCR to identify the percentage of mutant and wild-type alleles. Clinical samples from patients with cancer with known SF3B1 mutations were collected and tested to evaluate the assays' ability to detect SF3B1 mutations in ptDNA.

RESULTS
Patient samples showed SF3B1 K700E mutations within the ptDNA of 4 patients with acute leukemia and 3 with myelodysplastic syndrome who were known to harbor this mutation. A blood sample from a patient with lung cancer with a known SF3B1 V701F mutation was also analyzed and this mutation was successfully identified in ptDNA. However, 1 of the patients with a K700E mutation was found to have a mutational burden of 98%. After careful analysis of this locus by Sanger sequencing and ddPCR, this patient was found to have an SNP (R702R), which prevented binding of the ddPCR wild-type probe to its cognate allele.

CONCLUSIONS
These results further support that ddPCR-based assays may be valuable companion diagnostics for the identification and monitoring of patients with cancer, but the results also emphasize the need to identify SNPs at loci that are being analyzed.
Adoção do ecodesign em empresas inovadoras no Brasil: levantamento e análise dos principais estímulos
Authors: Luiz João Victor Rojas , Andrade João Leonardo , Jugend Daniel , Da Silva Sérgio Luis , Luiz Octaviano Rojas , Souza Fernando Bernardi 
Published: June 2017

Embora o interesse pela questão ambiental tenha ganhado importância na área de gestão de operações nos últimos anos, observa-se ainda uma lacuna em pesquisas nacionais. Visando contribuir com esta área, a presente pesquisa tem como objetivo levantar e compreender quais são os principais estímulos para a adoção do ecodesign em empresas no país. Foi realizada uma pesquisa de levantamento do tipo survey em 79 firmas pertencentes a setores inovadores e envolvidas em atividades de desenvolvimento de novos produtos. Dentre os principais resultados observou-se que o atendimento aos requisitos legais e possibilidades de novas oportunidades de negócios se sobressaem como os principais estímulos para a adoção do ecodesign. A utilização do ecodesign como elemento para a redução de custos também é incentivo considerado relevante pelas empresas. Por outro lado, o “benefício ao meio ambiente” é tido como o estímulo menos atrativo.
Impact of marbling art therapy activities on the anxiety levels of psychiatric patients
Authors: Utaş Akhan Latife , Atasoy Nuray 
Published: June 2017

Purpose: Study was conducted to explore the impact of marbling art therapy on the anxiety levels of patients with schizophrenia and bipolar disorder.Methods: Data for the study were at a university hospital and in the psychiatric service,polyclinic of a State Hospital with 34 patients diagnosed with schizophrenia and 34 patients diagnosed with bipolar disorder. Investigations were carried out with study groups and a control group.Findings:Following marbling, it was found that there were significant decreases in the PANSS negative, in the positive, general psychopathology in terms of the scores of the group of schizophrenia patients and in the BAI scores of patients with bipolar disorder.There was no significant difference in the BAI scores of the control group.Clinical relevance:The study showed that the method of marbling therapy led to improvements in the negative and positive symptoms of schizophrenic patients and in both patient groups, it contributed to decreasing levels of anxiety.
Menentukan Prioritas Penanganan Ruas Jalan Nasional di Pulau Bangka
Authors: Benardus Munthe Raymond , Hario Setiadji Bagus , Darsono Suseno 
Published: June 2017

National road are crucial to the economy and it spurs the economic development potential of the area contained in the province of Bangka Belitung Archipelago. National road lines is the busiest traffic lane linking inter-cities/regencies in Bangka Island requires maximum handling but the ability of the central government in providing funding is very limited. Prioritization of road handling must be done evenly as needed so that the purpose of the existence of these roads remains unfulfilled. The purpose of this study was to determine the priority handling of national road Lines in Bangka Island by the method of Analytical Hierarchy Process (AHP) using 6 (six) criteria. Data results of the questionnaire showed that of 6 (six) criteria taken in this study namely accessibility (19.3%) is the most dominant criteria. Followed mobility (17.6%), the condition of roads (17.1%), current road segment (16.3%), the development of regional (15.9%), and Economic of Gross Regional Domestic Product (13.8%). By entering the 6 (six) criteria to 21 segments, the roads segment that became the priority of road handling is Sungailiat – Boundary of Pangkalpinang followed Tanjung Gudang - Lumut, and the next successive.
Penyelesaian Numerik Advection Equation 1 Dimensi dengan EFG-DGM
Authors: Sadono Kresno Wikan 
Published: June 2017

Differential equation can be used to model various phenomena in science and engineering. Numerical method is the most common method used in solving DE. Numerical methods that popular today are finite difference method (FDM), finite element method (FEM) dan discontinuous Galerkin method (DGM), which the method includes mesh based. Lately, the developing methods, that are not based on a mesh, which the nodes directly spread in domain, called meshfree or meshless. Element free Galerkin method (EFG), Petrov-Galerkin meshless (MLPG), reproducing kernel particle method (RKPM) and radial basis function (RBF) fall into the category meshless or meshfree. Time integration generally use an explicit Runge Kutta 4th order, Newmark- , HHT- , Wilson- dll. This research was carried out numerical simulations DE, by combining the EFG method to solve the domain space and time integration with DGM methods. EFG using the complete order polynomial 1, and DGM used polynomial order 1. The equation used advection equation in one dimension. EFG-DGM comparison with analytical results also performed. The simulation results show the method EFG-DGM match the one-dimensional advection equations well.
Korelasi Skid Resistance dengan Kedalaman Tekstur pada Permukaan Perkerasan Lentur
Authors: Pandia Indra Jaya , Lubis Adina Sari , Rambe Andy Putra 
Published: June 2017

Skid Resistance is the force generated between the pavement surface and vehicle’s tires to resist the vehicle advance motion when braking. In this research the correlation between skid resistance value and texture depth on the pavement surface will be determined. The skid resistance value determined by using the British Pendulum Tester (BPT) and to determine the texture depth used Sand Patch Method. The research is conducted directly on a macro textured surface with two methods. The first method is applied on Ngumban Surbakti Road where the samples tested with the same distance from the edge of the pavement along the road; The second method is applied on Jend. Sudirman Road where the samples tested with specific distances from the edge of the pavement until the median. From the results of the analysis, there are some conclusions: (1) there is a positive correlation between the texture depth and skid resistance with a coefficient of determination (R2) = 0.028 on Ngumban Surbakti Road and (R2) = 0.191 on Jend. Sudirman Road;(2) the increase of skid resistance value is directly proportional to the increase of surface texture depth value; and (3) the different methods did not cause significant yield differences.
A self-configurable fault detection system for Industrial Ethernet networks
Authors: Windmann Stefan , Niggemann Oliver 
Published: June 2017

Abstract
In this paper, a self-configurable fault detection system for automated production systems with Industrial Ethernet is
proposed. The scope of the proposed fault detection system are process variables, i.e., the observed actuator and sensor
signals. Self-configuration of the fault detection system is enabled by recording and analyzing the link connection of the
Ethernet network during system start. In a subsequent training phase, a knowledge base is automatically built from the
observed process variables. Knowledge-based fault detection is accomplished once the knowledge base is established. Fault
detection has been evaluated for a glue production process. In this application case, the knowledge-based fault detection
method yielded a balanced accuracy of 99.81%, while a model-based method, which has been used as reference,
produced a balanced accuracy of 93.11%.
CFD Simulation of Flow Through the Reconstructed Microstructure of Fibrous Gas Diffusion Layer in a Polymer Electrolyte Membrane Fuel Cell
Authors: Patnaikuni Venkata Suresh , Jayanti Sreenivas 
Published: June 2017

AbstractThe gas diffusion layer (GDL) is one of the key components in a polymer electrolyte membrane (PEM) fuel cell. Generally it is a carbon-based fibrous medium that allows for the transport of electrons through the fibers and distributes the reactants through the void space to the catalyst layer in a PEM fuel cell. In the present work, a microstructure study of reactant transport is carried out by reconstructing the typical fibrous microstructure of the GDL and investigating the transport characteristics of the porous medium using computational fluid dynamics (CFD) simulations. The results confirm the applicability of Darcy’s law formulation for permeability determination and Bruggemann correction for calculation of effective diffusivity for typical conditions encountered in PEM fuel cells. Macroscopic material properties such as through-plane and in-plane permeabilities and effective diffusion coefficient are determined and compared against experimental values reported in the literature.
Murder Among Relatives
Authors: Carlà-Uhink Filippo 
Published: June 2017

AbstractThis article provides a thorough analysis of two Roman institutions: the vitae necisque potestas and the regulation of parricidium. Moving from the traditional interpretations of these institutions, connected to a supposedly very high degree of violence inside Roman families, the article demonstrates that they were no relicts of an “archaic” society, but a specific historical formation, connected with the “cultural revolution” of the third and second centuries BCE. In particular, this article shows that both the power of the pater familias to kill his relatives (which was not as absolute as often assumed) and the special position taken by the murder of relatives in the Roman juridical system and mentality, must be read against the background of the negotiation between the central institutions of the Republic and the autonomy sphere of the gentes.
Educación emocional en la universidad: propuesta de actividades para el desarrollo de habilidades sociales y personales / Emotional education in the university: proposed activities for development of the social and personal abilities
Authors: Mira Agulló José Gabriel , Parra-Meroño María Concepción , Beltrán Bueno Miguel Ángel 
Published: June 2017

La educación emocional es en sí misma una innovación educativa, que surge de la necesidad de satisfacer las necesidades sociales que no son atendidas por la educación, con las materias docentes o académicas ordinarias. Ante la carencia observada en la práctica docente, en este trabajo se proponen una serie de actividades que contribuyen al desarrollo y refuerzo de la Inteligencia emocional para mejorar la formación integral del alumno. Para ello, se diseñan y programan un conjunto de actividades que permiten completar la formación del alumno, mejorando su competencia emocional, desarrollando habilidades sociales que proporcionarán una mejor inserción laboral.
Arturo Uslar Pietri y sus editores / Arturo Uslar Pietri and his publishers
Authors: Febres de Ayala Laura Margarita 
Published: June 2017

En la Casa de Estudio de la Historia de Venezuela, Lorenzo A. Mendoza Quintero, se encuentra el archivo de la correspondencia de Arturo Uslar Pietri. En este trabajo analizaremos de esa gran cantidad de cartas, solo aquellas que tienen relación con sus editores. Estas cartas se encuentran fechadas entre 1946 y 1984, años en los cuales Uslar Pietri mantuvo contacto con las editoriales para la publicación de sus obras. Buena parte de estas cartas provienen de la caja número 060.001-060044 carpeta 060.011 que lleva por título Editorial Losada, otras de su epistolario con figuras importantes del mundo editorial como Guillermo De Torre y Carmen Ballcells. Pero también con autores que publicaban junto con él quienes compartían las experiencias de este proceso como Miguel Ángel Asturias y Luis Beltrán Guerrero. Nuestro objetivo con este trabajo es comunicar la importancia que tiene el mercado editorial para la difusión de la obra de los autores latinoamericanos y hemos tomado el caso concreto de Arturo Uslar Pietri porque contamos con la documentación necesaria para hacer un análisis de parte de esta trayectoria, circunstancia que no es a veces posible con otros autores porque no se guardó la documentación necesaria para hacer un estudio con esta temática. La conclusión a que llegamos es que aunque estamos hablando de un autor con un gran prestigio intelectual nacional e internacional, tuvo problemas con sus editoriales que generalmente no eran puntuales en cancelarle sus honorarios. Sin embargo, también escuchamos las voces de los editores, como la de Gonzalo Losada por medio de las cuales observamos que el trabajo de las editoriales en Latinoamérica no está exento de riegos legales y económicos que expondremos en este trabajo.
High-Temperature Mechanical Properties of P91 Weld Metal
Authors: Rivolta B. , Tavasci F. , Gerosa R. , Yenus J. 
Published: June 2017

Abstract
Increasing temperature is one of the key factors for improving the efficiency of steam power plants. Important metallurgical phenomena are activated at such high temperatures and creep resistance becomes a driving criterion for the material selection. Ferritic steels, including 2Cr, 9Cr, and 12Cr steels, are among the best candidates; their continuous development and optimization with the addition of Mo, V, Nb, and W have resulted in a significant improvement in creep strength together with a good weldability. This study investigates the high-temperature mechanical properties of two Grade 91 welded plates and focuses on the creep behavior, proposing a modified expression of the Larson–Miller parameter for the estimation of critical combinations of temperature, stress, and time, which could lead to rupture. The suggested parameter, which is highly sensitive to temperature, is able to outline the criticality of the welding and it is useful for predicting the duration of a creep test with the specimen rupture.
A post‐translational modification switch controls coactivator function of histone methyltransferases G9a and GLP
Authors: Poulard Coralie , Bittencourt Danielle , Wu Dai‐Ying , Hu Yixin , Gerke Daniel S , Stallcup Michael R 
Published: June 2017

AbstractLike many transcription regulators, histone methyltransferases G9a and G9a‐like protein (GLP) can act gene‐specifically as coregulators, but mechanisms controlling this specificity are mostly unknown. We show that adjacent post‐translational methylation and phosphorylation regulate binding of G9a and GLP to heterochromatin protein 1 gamma (HP1γ), formation of a ternary complex with the glucocorticoid receptor (GR) on chromatin, and function of G9a and GLP as coactivators for a subset of GR target genes. HP1γ is recruited by G9a and GLP to GR binding sites associated with genes that require G9a, GLP, and HP1γ for glucocorticoid‐stimulated transcription. At the physiological level, G9a and GLP coactivator function is required for glucocorticoid activation of genes that repress cell migration in A549 lung cancer cells. Thus, regulated methylation and phosphorylation serve as a switch controlling G9a and GLP coactivator function, suggesting that this mechanism may be a general paradigm for directing specific transcription factor and coregulator actions on different genes.