bluuebunny/crossref_metadata_2025_split huggingface dataset:
Groin Injuries (Athletic Pubalgia) and Return to Play
Authors: Elattar Osama , Choi Ho-Rim , Dills Vickie D. , Busconi Brian 
Published: June 2016

Context: Groin pain is a common entity in athletes involved in sports that require acute cutting, pivoting, or kicking such as soccer and ice hockey. Athletic pubalgia is increasingly recognized as a common cause of chronic groin and adductor pain in athletes. It is considered an overuse injury predisposing to disruption of the rectus tendon insertion to the pubis and weakness of the posterior inguinal wall without a clinically detectable hernia. These patients often require surgical therapy after failure of nonoperative measures. A variety of surgical options have been used, and most patients improve and return to high-level competition. Evidence Acquisition: PubMed databases were searched to identify relevant scientific and review articles from January 1920 to January 2015 using the search terms groin pain, sports hernia, athletic pubalgia, adductor strain, osteitis pubis, stress fractures, femoroacetabular impingement, and labral tears. Study Design: Clinical review. Level of Evidence: Level 4. Results and Conclusion: Athletic pubalgia is an overuse injury involving a weakness in the rectus abdominis insertion or posterior inguinal wall of the lower abdomen caused by acute or repetitive injury of the structure. A variety of surgical options have been reported with successful outcomes, with high rates of return to the sport in the majority of cases.
Disrupted white matter integrity is associated with cognitive deficits in patients with amnestic mild cognitive impairment: An atlas-based study
Authors: Liu Duan , Wang Zan , Shu Hao , Zhang Zhijun 
Published: June 2016

Objective: This study investigated white matter integrity in patients with amnestic mild cognitive impairment by diffusion tensor imaging. Methods: A total of 83 patients with amnestic mild cognitive impairment and 85 elderly healthy controls underwent neuropsychological testing and a diffusion tensor imaging scan. Whole-brain white matter data were parcellated into 50 regions based on the anatomical ICBM-DTI-81 atlas, and regional diffusion metrics consisting of fractional anisotropy, mean diffusivity, radial diffusivity, and axial diffusivity were calculated for each region. Diffusion tensor imaging indices were compared between groups, and it was determined that between-group differences were significantly correlated with neurocognitive performance. Results: Relative to the healthy controls group, the amnestic mild cognitive impairment group exhibited poorer cognitive performance in all neuropsychological tests except the complex figure test ( p = 0.083) and showed decreased mean fractional anisotropy in the fornix, increased mean diffusivity in the fornix and bilateral uncinate fasciculus, elevated axial diffusivity in the fornix and genu of corpus callosum, and elevated radial diffusivity in the fornix and bilateral uncinate fasciculus ( p < 0.05). Behaviorally, integrity of the bilateral uncinate fasciculus was correlated positively with episodic memory function, while left uncinate fasciculus integrity was positively associated with language function in the amnestic mild cognitive impairment group ( p < 0.05). Conclusion: White matter abnormalities in neural pathways associated with memory were correlated with neurocognitive deficiencies in amnestic mild cognitive impairment. Given that amnestic mild cognitive impairment is putatively a prodromal syndrome for Alzheimer’s disease, this study furthers our understanding of the white matter changes associated with Alzheimer’s disease pathogenesis in the predementia stage.
Chronic intestinal pseudo-obstruction associated with enteric ganglionitis in a Persian cat
Authors: Mortier Jeremy , Elissalt Estelle , Palierne Sophie , Semin Marie Odile , Delverdier Maxence , Diquélou Armelle 
Published: June 2016

Case summary A 7-year-old neutered male Persian cat was presented for acute vomiting and inappetence. Physical examination revealed severe abdominal distension. Radiographs demonstrated pneumoperitoneum, megaoesophagus and generalised gaseous distension of the digestive tract. Exploratory coeliotomy was performed, revealing markedly distended and thickened small and large intestines with no observable peristalsis. No intestinal perforation was present. Bacteriological and cytological analysis of abdominal fluid revealed a septic peritonitis involving Pasteurella multocida. Full-thickness intestinal biopsies demonstrated lymphocytic ganglioneuritis localised to the enteric nervous system, in association with glandular atrophy and muscular layer hypertrophy. Amoxicillin-clavulanate and analgesics were given. The cat’s general condition gradually improved after the addition of pyridostigmine bromide (0.5 mg/kg q12h PO), initiated 3 days postsurgery. Vomiting resolved and did not recur. Follow-up radiographs at 15 days, and 1 and 6 months showed persistent intestinal ileus, milder than on the pretreatment radiographs. Thirty months after presentation the cat is still alive, without clinical signs, and receives 1 mg/kg q12h pyridostigmine. Relevance and novel information To our knowledge, this is the first case of ganglioneuritis of the myenteric plexus described in cats, as well as the first one successfully treated with pyridostigmine. Chronic intestinal pseudo-obstruction is a very rare condition in cats but should be included in the differential diagnosis of generalised gastrointestinal ileus.
Accuracy of the Yamax CW-701 Pedometer for measuring steps in controlled and free-living conditions
Authors: Coffman Maren J , Reeve Charlie L , Butler Shannon , Keeling Maiya , Talbot Laura A 
Published: June 2016

Objective The Yamax Digi-Walker CW-701 (Yamax CW-701) is a low-cost pedometer that includes a 7-day memory, a 2-week cumulative memory, and automatically resets to zero at midnight. To date, the accuracy of the Yamax CW-701 has not been determined. The purpose of this study was to assess the accuracy of steps recorded by the Yamax CW-701 pedometer compared with actual steps and two other devices. Methods The study was conducted in a campus-based lab and in free-living settings with 22 students, faculty, and staff at a mid-sized university in the Southeastern US. While wearing a Yamax CW-701, Yamax Digi-Walker SW-200, and an ActiGraph GTX3 accelerometer, participants engaged in activities at variable speeds and conditions. To assess accuracy of each device, steps recorded were compared with actual step counts. Statistical tests included paired sample t-tests, percent accuracy, intraclass correlation coefficient, and Bland–Altman plots. Results The Yamax CW-701 demonstrated reliability and concurrent validity during walking at a fast pace and walking on a track, and in free-living conditions. Decreased accuracy was noted walking at a slow pace. Conclusions These findings are consistent with prior research. With most pedometers and accelerometers, adequate force and intensity must be present for a step to register. The Yamax CW-701 is accurate in recording steps taken while walking at a fast pace and in free-living settings.
Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase–dependent calcium stores
Authors: Elaïb Ziane , Adam Frédéric , Berrou Eliane , Bordet Jean-Claude , Prévost Nicolas , Bobe Régis , Bryckaert Marijke , Rosa Jean-Philippe 
Published: June 2016

Key PointsDefect in thrombus formation, platelet aggregation, and ADP secretion induced by ablation or inhibition of SERCA3−/−.
Surface IgM expression and function are associated with clinical behavior, genetic abnormalities, and DNA methylation in CLL
Authors: D’Avola Annalisa , Drennan Samantha , Tracy Ian , Henderson Isla , Chiecchio Laura , Larrayoz Marta , Rose-Zerilli Matthew , Strefford Jonathan , Plass Christoph , Johnson Peter W. , Steele Andrew J. , Packham Graham , Stevenson Freda K. , Oakes Christopher C. , Forconi Francesco 
Published: June 2016

Key Points
High sIgM level is a potential key factor associated with poorer clinical outcome in CLL. Genetic and epigenetic features influence sIgM levels and function in CLL.
Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia
Authors: Hunter Zachary R. , Xu Lian , Yang Guang , Tsakmaklis Nicholas , Vos Josephine M. , Liu Xia , Chen Jie , Manning Robert J. , Chen Jiaji G. , Brodsky Philip , Patterson Christopher J. , Gustine Joshua , Dubeau Toni , Castillo Jorge J. , Anderson Kenneth C. , Munshi Nikhil M. , Treon Steven P. 
Published: June 2016

Key Points
Transcription profiles associated with mutated MYD88, CXCR4, ARID1A, abnormal cytogenetics including 6q−, and familial WM are described. Mutated CXCR4 profiles show impaired expression of the tumor suppressor response induced by MYD88L265P and also G-protein/MAPK inhibitors.
Cost Savings from Home and Community-Based Services: Arizona’s Capitated Medicaid Long-Term Care Program
Authors: Weissert William G. , Lesnick Timothy , Musliner Melissa , Foley Kathleen A. 
Published: June 2016

The Arizona Long-Term Care System is the first capitated, long-term care Medicaid program in the nation to operate statewide. It promotes an extensive home and community-based services program intended to lower long-term care costs by substituting home care for institutional care. Because the program is statewide, finding a suitable control group to evaluate it was a serious problem. A substitute strategy was chosen that compares actual costs incurred to an estimate of what costs would have been in the absence of home and community-based (HCB) services.
To estimate the likelihood of institutionalizing clients in the absence of HCB services, coefficients for institutionalization risk factors were estimated in a logistic regression model developed using national data. These were applied to characteristics of Arizona clients. The model assigned approximately 75 percent of the program’s clients to a category with traits that were determined to resemble nursing home residents’ traits. A similar methodology was used to estimate lengths of nursing home stays. Lengths of stay by the program’s nursing home patients were regressed on their characteristics using an event history analysis model. Coefficients for these characteristics from the regression analysis were then applied to HCB services clients to estimate how long their nursing home stays would have lasted, had they been institutionalized. These estimated nursing home stays were generally shorter than these same patients’ observed home and community stays.
Risk of institutionalization was then multiplied by estimated length of stay and by monthly nursing home costs to estimate what costs would have been without the HCB services option. The expected costs were compared to actual costs to judge cost savings. Home and community-based services appeared to save substantial amounts on costs of nursing home care. Estimates of savings were very robust and did not appear to be declining as the program matured. Savings probably came from several sources: the assessment teams that judged client eligibility were employed by a state agency and thus were independent from the program contractors; clients were required to be in need of at least a three-month nursing home stay; a cap was placed on the number of HCB services clients contractors were allowed to serve each month; the capitated payment methodology forced managed care contractors to hold down average HCB services costs or lose money; and the HCB services and nursing home costs were blended in the capitated rate, so that plans that failed to place clients in HCB services would lose money by using more nursing home days than their monthly capitated rate allowed.
The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell–cell trans-dimerization of Na,K-ATPase β1 subunits
Authors: Tokhtaeva Elmira , Sun Haying , Deiss-Yehiely Nimrod , Wen Yi , Soni Pritin N. , Gabrielli Nieves M. , Marcus Elizabeth A. , Ridge Karen M. , Sachs George , Vazquez-Levin Mónica , Sznajder Jacob I. , Vagin Olga , Dada Laura A. 
Published: June 2016

ABSTRACT
FXYD5 (also known as dysadherin), a regulatory subunit of the Na,K-ATPase, impairs intercellular adhesion by a poorly understood mechanism. Here, we determined whether FXYD5 disrupts the trans-dimerization of Na,K-ATPase molecules located in neighboring cells. Mutagenesis of the Na,K-ATPase β1 subunit identified four conserved residues, including Y199, that are crucial for the intercellular Na,K-ATPase trans-dimerization and adhesion. Modulation of expression of FXYD5 or of the β1 subunit with intact or mutated β1–β1 binding sites demonstrated that the anti-adhesive effect of FXYD5 depends on the presence of Y199 in the β1 subunit. Immunodetection of the plasma membrane FXYD5 was prevented by the presence of O-glycans. Partial FXYD5 deglycosylation enabled antibody binding and showed that the protein level and the degree of O-glycosylation were greater in cancer than in normal cells. FXYD5-induced impairment of adhesion was abolished by both genetic and pharmacological inhibition of FXYD5 O-glycosylation. Therefore, the extracellular O-glycosylated domain of FXYD5 impairs adhesion by interfering with intercellular β1–β1 interactions, suggesting that the ratio between FXYD5 and α1–β1 heterodimer determines whether the Na,K-ATPase acts as a positive or negative regulator of intercellular adhesion.
Αναζήτηση στο Διαδίκτυο με Χρήση Μεθόδων Γραμμικής Άλγεβρας
Authors: Αρβανιτογεώργος Ανδρέας 
Published: June 2016

Τα τεχνολογικά προβλήματα που παρουσιάζονται στο σύγχρονο κόσμο είναι ιδιαίτερα περίπλοκα και προκειμένου να κατανοηθούν πληρέστερα, συχνά απαιτούν μια μαθηματική περιγραφή. Ένα χαρακτηριστικό παράδειγμα είναι η αναζήτηση ιστοσελίδων στο διαδίκτυο με τέτοιον τρόπο, ώστε να παρουσιάζονται στο χρήστη οι ιστοσελίδες που τον αφορούν περισσότερο. Ο τεράστιος όγκος της διαθέσιμης πληροφορίας απαιτεί μια συντονισμένη μαθηματική προσέγγιση και μια τέτοια μαθηματική μέθοδος χρησιμοποιείται από τη μηχανή αναζήτησης Google. Στην παρούσα εργασία παρουσιάζουμε τη θεμελίωση της μεθόδου αυτής χρησιμοποιώντας γραμμική άλγεβρα, καθώς και μερικές δυσκολίες που προκύπτουν κατά την εφαρμογή της.
Μελέτη της μη αγγειακής καρκινικής ανάπτυξης μέσω ενός πεπλατυσμένου σφαιροειδούς προτύπου
Authors: Γραικού Αικατερίνη 
Published: June 2016

Στη μάχη για την αντιμετώπιση του καρκίνου καλούνται τα μαθηματικά, σε συνεργασία με τη Βιολογία και την Κλινική Ιατρική, να αναπτύξουν θεωρητικά πλαίσια που να ενσωματώνουν και να ερμηνεύουν τα συνεχώς αυξανόμενα πειραματικά αποτελέσματα της Βιοτεχνολογίας και να δημιουργήσουν μοντέλα που θα ερμηνεύουν τους μηχανισμούς και θα προβλέπουν την εξέλιξη της νόσου. Πλήθος μαθηματικών προτύπων έχουν αναπτυχθεί τα τελευταία χρόνια, που μοντελοποιούν τις τρεις φάσεις της καρκινικής ανάπτυξης. Η μη αγγειακή φάση στα περισσότερα μοντέλα μελετάται σε σφαιρικό σχήμα γιατί στα in vitro πειράματα οι καλλιεργούμενοι όγκοι προσομοιάζουν σφαίρες. Υπάρχουν όμως όγκοι που θα μπορούσαν να περιγραφούν καλύτερα από μία γεωμετρία που παρέχει διπαραμετρική προσέγγιση του σχήματος τους, όπως η πεπλατυσμένη σφαιροειδής γεωμετρία. Η παρούσα εργασία εστιάζει στην περιγραφή των γενικών αρχών και φυσικών νόμων που διέπουν την ανάπτυξη ενός καρκινικού όγκου σε σχήμα πεπλατυσμένου σφαιροειδούς. Ο όγκος αναπτύσσεται υπό την επίδραση διαχεόμενων θρεπτικών συστατικών από το περιβάλλον, ενδογενών ανασταλτικών ουσιών που παράγονται από τη μεταβολική και αποσυνθετική διαδικασία των κυττάρων του καθώς και της πίεσης που έπεται από την ανάπτυξή του στο εσωτερικό πεπερασμένου φιλοξενούντος οργάνου. Κατά συνέπεια, το μαθηματικό πρόβλημα, το οποίο στην παρούσα εργασία αντιμετωπίζεται αναλυτικά, είναι ένα πρόβλημα ελευθέρου συνόρου με μερικές διαφορικές εξισώσεις.
Trophic application in CVI I with peripheral oedema compared with compression stockings
Authors: Kiesewetter H. 
Published: June 2016

Summary
Aim In the warm season of 2015, the efficacy of Allga Med® Antiswelling Foot Spray and Allga Med® Warm Feet Balsam in combination with a class 2 compression stocking was compared with the efficacy of a compression stocking of the same class applied alone.
Method 40 women aged 23–78 years (mean 48 years) were included in the investigation. The women were all overweight (mean height: 166 cm, mean weight: 83 kg; mean BMI 30.1 kg/m2). For one month before their inclusion, they had not been permitted to take venous medication or wear compression stockings. Prior to the start of the study, class 2 compression stockings were prescribed. The compression stockings were worn consistently during the day for 14 days. In addition, the right leg was treated twice daily with foot spray and balsam. Before the start of the study and after 14 days, the foot and distal lower leg volume of both legs was measured by means of water plethysmography
Result On the stockinged left leg, the volume decreased by 152 ml. On the right leg, which was trophically treated and stockinged, the volume decreased by up to 335 ml.
Phylogeny and biogeography of Caryodaphnopsis (Lauraceae) inferred from low‐copy nuclear gene and ITS sequences
Authors: Li Lang , Madriñán Santiago , Li Jie 
Published: June 2016

AbstractCaryodaphnopsis is a small genus of the Lauraceae. It contains 16 known species with a disjunct tropical amphi‐Pacific distribution; 8 species in tropical Asia and 8 species in tropical America. In the present study, RPB2, LEAFY and ITS sequences of 9 Caryodaphnopsis species and 22 other Lauraceae species were analyzed with maximum parsimony and Bayesian inference. Divergence time estimation employed the Bayesian Markov chain Monte Carlo method under a relaxed clock. Ancestral area reconstructions were conducted by using both the statistical dispersal‐vicariance analysis and likelihood approach under the dispersal‐extinction‐cladogenesis model. Based on the results of the phylogenetic analyses, the monophyly of Caryodaphnopsis is strongly supported. Asian and American Caryodaphnopsis species form two well‐supported monophyletic clades, respectively. Independent lineages for Caryodaphnopsis, Neocinnamomum and Cassytha are also suggested. According to the divergence time estimations and ancestral area reconstructions, we suggest that Caryodaphnopsis originated in Late Cretaceous Laurasia and its amphi‐Pacific disjunction results from the disruption of ancestral boreotropical lineages between Eurasia and North America during the first cooling period of the Eocene.
Typification of the Indo‐Pacific seagrass Enhalus acoroides (Hydrocharitaceae)
Authors: Boisset Fernando , Ferrer-Gallego Pablo P. 
Published: June 2016

AbstractThe typification of the ecologically important and widely distributed Indo‐Pacific seagrass Enhalus acoroides (≡ Stratiotes acoroides, Hydrocharitaceae) is discussed. An illustration from Rumphius's Herbarium Amboinense is designated as the lectotype.
Features of the development of the course «Communicative technologies in the service»
Authors: Ермакова Елена , Ermakova Elena 
Published: June 2016

The article is devoted to the design of the training course «Communicative technologies in the service». It is noted
that in recent times, domestic education is increasingly focused on practical disciplines and subjects, so the role
and value of applied knowledge grow, and with it problems of its implementation (teaching) in classically oriented
high schools, traditionally focused on theoretical knowledge. This «gap» may be overcome if you understand the
imbalances and design disciplines, with the latest knowledge, gleaned mostly from foreign business literature. It
became the basis for the design of the course «Communicative technologies in the service» (manual, trainingmethodical
complex, series of lectures, training). The course is built on the basis of the following considerations: to
avoid duplication with adjacent (previous and subsequent) disciplines; a basic understanding of the terms «communication
» and «contact»; practice-oriented approach to serving and learning; networking of communicative
theory with «service»; the great role of independent work at studying of discipline. Quotations from contemporary
business literature and practices of various communication strategies, including the material of our region – the
Tyumen region play the major role in the course. Methodologically, the discipline focuses on the new direction
of development of Tyumen state University as a University of global competitiveness and its mission is «training
people who are capable to design new activities, to transform the social environment and create successful businesses
in the face of global competition».
Methodical bases of formation of color perception of children of preschool and younger school age
Authors: Березина Юлия , Berezina Yuliya , Князева Олена , Knyazeva Olena 
Published: June 2016

The article is devoted to the topical problem of formation of color perception of children of preschool and younger school age in artistic and creative activities. The perception of color is defined by the authors as the process of understanding color, which basic laws are integrity, understanding, apperception, selectivity and constancy. Analysis of the age stages of formation of color perception led to the conclusion that the stages are associated with the environment in which a child grows: experience of color perception in reality, in works of fine art and experience of the own artistic and creative activities, expert help of the teacher. Therefore, the formation of color perception skills of children of preschool and younger school age needs systematic work in the dynamics of preschool children
development of colour standards through the expansion of the primary school children’s views about the color and perfection of color skills to the cognition of color as a tool of the artist, which is able to express feelings, emotions and relation. The authors developed methodological recommendations for the formation of color vision in children of preschool and younger school age: the active position of a teacher, the creation of an atmosphere of co-creation, experimentation; demonstration of techniques for working with color; the organization of perception process of art works, including the analysis of a color system in art and nature; the creation of a special aesthetic environment of a group class. The results of the study can be used in the process of teaching and learning fine arts in the design of individual routes of teachers self-education and personality developing educational technologies in system of improvement of teachers professional skill.
Employment Nondiscrimination Acts and Corporate Innovation
Authors: Gao Huasheng , Zhang Wei 
Published: June 2016

We show that U.S. state-level employment nondiscrimination acts (ENDAs)—laws that prohibit discrimination based on sexual orientation and gender identity—spur innovation. We find a significant increase in patents and patent citations for firms headquartered in states that have passed ENDAs relative to firms headquartered in states that have not. This result is more pronounced for firms that previously have not implemented pro-gay nondiscrimination policies, for firms in states with a large homosexual population, and for firms in human capital-intensive industries. Lastly, we provide evidence suggesting that ENDAs affect innovation by matching employees, who are generally more creative than anti-gay employees, with innovative firms. This paper was accepted by Gustavo Manso, finance.