bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Drug Distribution Systems on Nurses' Time Involvement in Medication Related Activities in Long Term Care Facilities
Authors: Farner James , Hicks Charles I. 
Published: July 2017

This investigation involves the impact of unit dose drug distribution systems upon nursing time involvement in medication related activities. Medication related activities included inventory and control, controlled substance activities, Kardex preparation, medication preparation, medication administration, and charting fulfillment. Two unit dose systems, one with a twenty-four hour medication supply and the other with a seventy-two hour medication supply were compared with a traditional drug distribution system using the time-motion study technique of work sampling. The traditional, twenty-four hour unit dose, and seventy-two hour unit dose required, respectively 3.22, 1.91, and 1.07 minutes per dose administered. The study found, using analysis of variance and t-tests, significant differences between the traditional and unit dose systems. The unit dose drug distribution systems significantly reduced nursing time involvement in controlled substance activities, medication preparation, medication administration, charting fulfillment, and total involvement in the medication cycle. Also, unit dose drug distribution systems might reduce nursing time involvement in inventory and controlled activities. In this study, the traditional system had an in-house pharmacy which assumed many inventory and control functions of the nurse that community pharmacies could not do under a traditional drug distribution system. Significant differences exist between unit dose drug distribution systems as shown in this study. Before implementing any unit dose drug distribution system, the pharmacist, nursing home administrator and director of nursing should examine the impact of any unit dose drug distribution system upon the medication cycle in their nursing home to maximize the benefits of unit dose drug distribution systems.
Ondansetron: A Serotonin Receptor (5-HT3) Antagonist for Antineoplastic Chemotherapy-Induced Nausea and Vomiting
Authors: Kohler David R. , Goldspiel Barry R. 
Published: July 2017

Ondansetron represents a new class of drugs that exert their antiemetic activity by selective inhibition of a serotonin receptor subtype (5-HT3). Ondansetron has marked activity against emesis associated with cisplatin and other highly emetogenic drugs. Compared with high doses of metoclopramide, the antiemetic “gold standard.” it demonstrates equal or superior efficacy. Although ondansetron is moderately well absorbed after oral administration, only a parenteral formulation will initially be available. Ondansetron is eliminated almost entirely by hepatic metabolism: less than five percent of an intravenously administered dose is recovered intact in urine. The half-life of ondansetron is approximately 3.5 hours: slightly shorter in children and prolonged in the elderly. Neither clinical efficacy nor adverse effects have correlated with serum concentrations. Ondansetron is generally well tolerated. Clinically relevant adverse effects include headache, diarrhea or constipation, sedation, and transient minor elevations of liver function tests. It is not associated with extrapyramidal reactions. Ondansetron is indicated as prophylaxis for nausea and vomiting associated with emetogenic chemotherapy. Studies to further evaluate and define its use are ongoing.
Clonal evolution and outcomes in myelofibrosis after ruxolitinib discontinuation
Authors: Newberry Kate J. , Patel Keyur , Masarova Lucia , Luthra Rajyalakshmi , Manshouri Taghi , Jabbour Elias , Bose Prithviraj , Daver Naval , Cortes Jorge , Kantarjian Hagop , Verstovsek Srdan 
Published: July 2017

Key Points
Survival of patients with MF after ruxolitinib discontinuation is poor, with median survival of 14 months. Low platelets at the start or end of therapy or clonal evolution while on therapy are associated with an even worse prognosis.
Recalibrating the risks and benefits of lithium therapy
Authors: Berk Michael , Cowdery Stephanie , Williams Lana , Malhi Gin S. 
Published: July 2017

SummaryRecent data might subtly recalibrate the risk/benefit ratio of lithium, the prototypical mood stabiliser for bipolar disorder. There are hints that lithium might be associated with a reduction in dementia risk and as noted in this Journal, a surprising reduction in the risk of cancer.
Maturação biológica e imagem corporal; sua relação com o sobrepeso/obesidade em escolares de Cacoal, Rondonia
Authors: Romanholo Rafael Ayres , Belo Carine , Baia Fernando Costa , Pereira Joeliton Elias , Lucena Adriano Robson Nogueira da , Prestes Jonato , Almeida Fabricio Moares de 
Published: July 2017

Introdução: Pesquisas de imagem corporal têm sido residuais e inconclusivas a respeito dos efeitos da morfologia do corpo sobre a insatisfação com o peso e a aparência física, que são o reflexo do amadurecimento individual. Objetivo: Verificar a relação da maturação biológica e imagem corporal com o excesso de peso em escolares de 7 a 12 anos de escolas municipais do município de Cacoal. Métodos: A amostra foi composta por 482 escolares de 7 a 12 anos, de ambos os sexos, sendo 111 da zona urbana e 371 na zona rural. Foram coletados valores referentes ao IMC Cole et al.,(2000), além de medidas de perímetro abdominal e foi identificada a maturação e a satisfação corporal dos escolares. O parâmetro para a mensuração da percepção da imagem corporal foi o protocolo proposto por Collins (1991), e para identificação dos estágios de maturação foi utilizado o protocolo de Tanner (1962). Para análise estatística, foi utilizado o programa SPSS 20.0 usando uma estatística descritiva em que foram calculados a média, o desvio padrão e o percentual; para comparar as médias dos grupos foi aplicada uma análise de variância para dois fatores (ANOVA) Two-way, e a aplicação do teste t-student. Resultados: Os resultados apontaram que a maturação nas meninas teve relação com a obesidade; o mesmo não foi evidenciado nos meninos. A satisfação com a imagem corporal também tem relação com a obesidade, circunstância em que as meninas são mais insatisfeitas com sua imagem corporal se comparadas aos meninos. Conclusão: Conclui-se que os resultados do presente estudo, mostram que a maturação nas meninas e sua imagem corporal têm relação com a obesidade.
When Is the Matching Polytope Box-Totally Dual Integral?
Authors: Ding Guoli , Tan Lei , Zang Wenan 
Published: July 2017

Let G = (V, E) be a graph. The matching polytope of G, denoted by P(G), is the convex hull of the incidence vectors of all matchings in G. As proved by Edmonds [10] [Edmonds J (1965) Maximum matching and a polyhedron with 0, 1-vertices, J. Res. Nat. Bur. Standards Sect. B 69(1–2):125–130.], P(G) is determined by the following linear system π(G): x(e) ≥ 0 for each e ∈ E; x(δ(v)) ≤ 1 for each v ∈ V; and x(E[U]) ≤ ½|U|⌋ for each U ⊆ V with |U| odd. In 1978, Cunningham and Marsh [6] [Cunningham W, Marsh A (1978) A primal algorithm for optimum matching. Balinski ML, Hoffman AJ, eds. Polyhedral combinatorics. Mathematical Programming Studies, Vol. 8 (Springer, Berlin), 50–72.] strengthened this theorem by showing that π(G) is always totally dual integral. In 1984, Edmonds and Giles [11] [Edmonds J, Giles R (1984) Total dual integrality of linear inequality systems. Progress in Combinatorial Optimization (Academic Press, Toronto), 117–129.] initiated the study of graphs G for which π(G) is box-totally dual integral. In this paper, we present a structural characterization of all such graphs, and develop a general and powerful method for establishing box-total dual integrality. The online appendix is available at https://doi.org/10.1287/moor.2017.0852 .
The effect of short-term and long-term application of fisetin on experimentally induced airway hyperreactivity
Authors: Kazimierová I. , Pappová L. , Šútovská M. , Fraňová S. 
Published: July 2017

Abstract

Background: Fisetin, a derivate from the flavonol group may possess a variety of pharmacological effects. The aim of the presented study was to evaluate the bronchodilatory effect of fisetin after the acute or the chronic administration to guinea pigs with allergic airway inflammation.

Methods: Experimental animals were sensitized and challenged by ovalbumin. Fisetin was administered in dose 5mg/kg/p.o., either once after the end of 21-days sensitization or daily during the 21-days sensitization. By using the whole-body plethysmograph, we monitored the specific airway resistance, a parameter of airway hyperreactivity in vivo. The changes of the specific airway resistance were evaluated after the short-term inhalation of the bronchoconstriction mediator-histamine (10−6 mol.1−1).

Results: Our results showed that the short-term as well as the long-term administration of fisetin caused decrease of the specific airway resistance values. The bronchodilatory effect of fisetin was comparable to the long-acting beta2 sympathomimetic – salmeterol after the long-term administration. The measurements of the bronchodilatory activity after single administration have revealed more prolonged effect of fisetin comparing to the short-acting beta2 sympathomimetic – salbutamol, as this remained even after the 5 hours, when salbutamol was already ineffective.

Conclusion: In conclusion, flavonol – fisetin has shown bronchodilatory potential. In the light of this fact, fisetin may represent potential substance that can be effective in both prevention as well as control of airway inflammation symptoms.
Standing Waves in One-Dimensional Resonator Containing an Ideal Isothermal Gas Affected by the Constant Mass Force
Authors: Perelomova Anna 
Published: July 2017

Abstract
The study is devoted to standing acoustic waves in one-dimensional planar resonator which containing an ideal gas. A gas is affected by the constant mass force. Two types of physically justified boundary conditions are considered: zero velocity or zero excess pressure at both boundaries. The variety of nodal and antinodal points is determined. The conclusion is that the nodes of pressure and antinodes of velocity do not longer coincide, as well as antinodes of pressure and nodes of velocity. The entropy mode may contribute to the total field in a resonator. It is no longer isobaric, in contrast to the case when the external force is absent. Examples of perturbations inherent to the entropy mode in the volume of a resonator are discussed.
Active Transient Acousto-Structural Response Control of a Smart Cavity-Coupled Circular Plate System
Authors: Hasheminejad Seyyed M. , Shakeri Rezgar 
Published: July 2017

Abstract
The transient vibroacoustic response suppression of a piezo-coupled sandwich circular plate backed by a rigid-walled cylindrical acoustic enclosure is investigated. Problem formulation is based on the linear acoustic wave theory, Kirchhoff thin plate model, fluid/structure compatibility relations, Rayleigh integra formula, and active damping control (ADC) strategy. Matlab’s Genetic Algorithm (GA) is utilized to identify and optimize the feedback controller gain parameter based on a multi-objective performance index function. Durbin’s numerical Laplace inversion scheme is then used to calculate the key acousto-structural response parameters due to a transverse impulsive shock force for selected cavity depths. Numerical simulations demonstrate satisfactory performance of adopted control methodology in effective suppression of panel displacement response and radiated external sound pressure for enclosures of shallow and moderate depths. Limiting cases are considered and accuracy of the proposed model is rigorously verified.
Evaluation of the Technical Condition of the Active Part of the High Power Transformer Based on Measurements and Analysis of Vibroacoustic Signals
Authors: Borucki Sebastian , Cichoń Andrzej , Majchrzak Henryk , Zmarzły Dariusz 
Published: July 2017

Abstract
This article presents the results of research connected with the development and industrial use of vibroacoustic methods for the evaluation of the technical condition of the active part of transformers. The article presents the results of the analysis of vibrations generated by the high power transformer in which a defect was found on the basis of tests of oil carried out using the chromatography tests. In order to confirm the damage of the active part of this transformer, vibroacoustic measurements were performed in three states of its operation. The measurement using the classical vibroacoustic method included the registration of vibrations at the idle speed and during the load operation of the transformer. The original diagnostic method, so-called the modified vibroacoustic method, was also used during the measurement. The analysis of signals recorded using the classical vibroacoustic method was carried out in the frequency domain by indicating the amplitude of even harmonic vibrations. However, the analysis of signals measured during the commissioning of the transformer was conducted in the time-frequency domain using the short-time Fourier transform (STFT), continuous wavelet transform (CWT), and discrete wavelet transform (DWT). On the basis of the analysis of the results obtained it was stated that the increased level of vibrations of this transformer is a consequence of the loss of rigidity of the mechanical structure of its core.
Circulating CD89-IgA complex does not predict deterioration of kidney function in Korean patients with IgA nephropathy
Authors: Jhee Jong Hyun , Kang Hye-Young , Wu Meiyan , Nam Bo Young , Chang Tae-Ik , Jung Su-Young , Park Seohyun , Kim Hyoungnae , Yun Hae-Ryong , Kee Youn Kyung , Yoon Chang-Yun , Park Jung Tak , Yoo Tae-Hyun , Kang Shin-Wook , Han Seung Hyeok 
Published: July 2017

AbstractBackground:Soluble CD89 (sCD89)-IgA complex plays a key role in the pathogenesis of IgA nephropathy (IgAN). However, there is a lack of evidence supporting this complex as a good biomarker for disease progression. This study aimed to evaluate the usefulness of sCD89-IgA complex for risk stratification of IgAN.Methods:A total of 326 patients with biopsy-proven IgAN were included. sCD89-IgA complex was measured by sandwich-enzyme-linked immunosorbent assay. The study endpoints were a 30% decline in estimated glomerular filtration rate (eGFR).Results:sCD89-IgA complex levels were inversely and weakly associated with eGFR at the time of biopsy (r=−0.12, p=0.03). However, the significance between the two factors was lost in the multivariate linear regression after adjustment of clinical factors (β=0.35, p=0.75). In a multivariate Cox model, the highest (hazard ratio [HR], 0.75; 95% confidence interval [CI], 0.35–1.61; p=0.45) and middle (HR, 0.93; 95% CI, 0.46–1.89; p=0.84) tertiles of sCD89-IgA complex levels were not associated with an increased risk of developing a 30% decrease in eGFR. Furthermore, the decline rates in eGFR did not differ between groups and C-statistics revealed that the sCD89-IgA complex were not superior to clinical factors in predicting disease progression.Conclusions:This study found no association between sCD89-IgA complex levels and disease progression in IgAN. Although sCD89 can contribute to the formation of immune complexes, our findings suggest that the sCD89-IgA level is not a good predictor of adverse outcomes and has limited clinical utility as a biomarker for risk stratification in IgAN.
Generalized Higher Derivations on Lie Ideals of Triangular Algebras
Authors: Ashraf Mohammad , Parveen Nazia , Wani Bilal Ahmad 
Published: July 2017

Abstract
Let be the triangular algebra consisting of unital algebras A and B over a commutative ring R with identity 1 and M be a unital (A; B)-bimodule. An additive subgroup L of A is said to be a Lie ideal of A if [L;A] ⊆ L. A non-central square closed Lie ideal L of A is known as an admissible Lie ideal. The main result of the present paper states that under certain restrictions on A, every generalized Jordan triple higher derivation of L into A is a generalized higher derivation of L into A.
Erratum to: Variations by generalized symmetries of local Noether strong currents equivalent to global canonical Noether currents
Authors: Palese Marcella 
Published: July 2017

Abstract
We correct misprints in a formula in the last sentence at the end of page 129; the first paragraph of subsection 4:1; misprints at the end of page 132 and in Proposition 1 at page 133 of the paper ‘Variations by generalized symmetries of local Noether strong currents equivalent to global canonical Noether currents’, Communications in Mathematics 24 (2016), 125-135. DOI: 10.1515/cm-2016-0009
One Hundred Years of the Galerkin Method
Authors: Repin Sergey 
Published: July 2017

Abstract
In 2016, the biennial conference Computational Methods in Applied Mathematics (CMAM) was dedicated to a remarkable event: the hundredth anniversary of the Galerkin method.
This special volume of the same name journal is mainly based on the papers of participants of this conference. The introductory article contains a brief description of the origin and development of the Galerkin method and gives an overview of the conference, which was held at the University of Jyväskylä (Finland), July 31 – August 6, 2016.
Influence of polyaniline/multiwalled carbon nanotube composites on alkyd coatings against the corrosion of carbon steel alloy
Authors: Farag Ahmed A. , Kabel Khalid I. , Elnaggar Elsayed M. , Al-Gamal Abdalrhman G. 
Published: July 2017

AbstractPolyaniline (PANI) and its composites with multiwalled carbon nanotubes (MWCNTs) were synthesized by chemical oxidative polymerization. High-resolution transmission electron microscopy (HR-TEM), thermogravimetric analysis (TGA), and Raman spectroscopy were used to characterize the investigated compounds. The synthesized composite is formulated as pigments in alkyd resin with different pigment-binder (P/B) ratios and investigated as anticorrosive coatings on carbon steel in 1mHCl using potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The protection mechanism of PANI occurred through the barrier and passivation effect on the carbon steel surface. The encapsulation and dispersion of MWCNTs into the PANI matrix promoted the anticorrosive efficiency of the alkyd coating.
Comparison of a Modified and Classic Fama-French Model for the Polish Market
Authors: Urbański Stanisław 
Published: July 2017

Abstract
This paper shows a comparison of the results of return, risk, and risk price simulation by a modified and classic Fama-French model. The modified model defines the new ICAPM state variable as a function of the structure of a company’s past financial results. The model tests are run on the basis of stocks listed on the Warsaw Stock Exchange. In light of the classic model the risk price, on the tested market, turned out univariate due to HML, however, in light of the modified model, risk price turned out to be threedimensional due to the proposed factors, and market portfolio. The factors of the modified model, compared with the HML and SMB, are widely perceived by portfolio managers, and the simulation results indicate a greater possibility to use this pricing application by large institutional investors.
Preliminary analysis of amplicon high-throughput sequencing as a method for the assessment of fungal diversity in discolored wood
Authors: Ma Xingxia , Jiang Mingliang , Liu Junliang , Deng Hao , Wang Shuangyong 
Published: July 2017

AbstractThe diversity of stain fungi is important if wood is inhabited with various fungi, and the discoloration mechanism will be better understood. MiSeq amplicon high-throughput sequencing (Illumina®) is able to detect species richness (the number of species within a community) and species evenness (the sizes of species populations within a community). This study detected fungal diversity in discolored Mongolian pine for the first time by the MiSeq approach, focusing on the nuclear ribosomal internal transcribed spacer-1 (ITS1). The results show that the discolored wood was inhabited by a combination of microorganisms, more than 90% of which belong toAscomycotafungi at the phylum level. The MiSeq method revealed not only all the inhabited fungal species but also their quantitative relation to each other. The dominant fungal species in sample A areHelotiales(34.1%) andHypocreales(20.7%). The dominant fungal species in sample B isNectriaceae(67.9%), whileHypocrea(34.7%) andSporothrix(27.6%) are the dominant fungal species in sample C. It was confirmed via core microbiome analysis that the following fungi were common stain fungi in the three discolored samples:Fusariumspp.,Aspergillusspp.,Sporothrixspp.,Penicilliumspp.,Trichodermaspp.,Alternariaspp. andCladophialophoraspp.
Modeling of the Hot Flow Behaviors for Ti-6Al-4V-0.1Ru Alloy by GA-BPNN Model and Its Application
Authors: Zhou Yu-ting , Xia Yu-feng , Jiang Lai , Long Shuai , Yang Dong 
Published: July 2017

AbstractA series of compression tests were performed on Ti-6Al-4V-0.1Ru titanium alloy in nine temperatures between 750 and 1150 °C and a strain rate range of 0.01 to 10s−1. The hot deformation behaviors of Ti-6Al-4V-0.1Ru showed highly non-linear intrinsic relationships with temperature, strain and strain rate. The flow curves exhibited different softening mechanisms, dynamic recrystallization (DRX) and dynamic recovery (DRV). In this study, the rheological behaviors of Ti-6Al-4V-0.1Ru were modeled using a special hybrid prediction model, where genetic algorithm (GA) was implemented to do a back-propagation neural network (BPNN) weights optimization, namely GA-BPNN. Subsequently, the predicted results were compared with experimental values and GA-BPNN model showed the ability to predict the flow behaviors of Ti-6Al-4V-0.1Ru with superior accuracy. Then a 3-D continuous interaction space was constructed to visually reveal the successive relationships among processing parameters. Finally, the predicted data were applied to process simulation and accuracy results were achieved.
Communities of message senders and recipients in legal settings and their communicative needs. The translator’s perspective
Authors: Matulewska Aleksandra 
Published: July 2017

Abstract
This presentation will be devoted to types of communities communicating in legal settings for various purposes. The author will focus on the communicative needs of message senders and recipients and communication strategies they may employ from the translator’s perspective. The focus of the presentation will be placed on the communication reality and the choice of the translation strategy which should be applied in the translation or interpretation process. The research hypothesis is put forward that the more homogeneous the communicative community of message senders and recipients is, the easier the translator’s choices in respect to the translation strategy are. Consequently, the more heterogenous the communicative community is, the more difficult it is to meet the expectations of all members of the community in question. The process of choosing sufficient equivalents requires determining the communicative needs of communication process participants. However, sometimes needs and expectations of communication process participants are contradictory. Additionally, not identifying communication problems properly may result in dire consequences affecting the life of persons involved in the process of communication in legal settings. The relations binding participants to communication may be very complex. The consequences of improper identification of communicative needs of message senders and recipients will be illustrated with real-life examples of such distortions in legal communication.