bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theoretical and Experimental Study on Boron β‐Diketonate Complexes with Intense Two‐Photon‐Induced Fluorescence in Solution and in the Solid State
Authors: Lanoë Pierre‐Henri , Mettra Bastien , Liao Yuan Yuan , Calin Nathalie , D'Aléo Anthony , Namikawa Tomotaka , Kamada Kenji , Fagès Fréderic , Monnereau Cyrille , Andraud Chantal 
Published: June 2016

AbstractThe front cover artwork is provided by the Chemistry for Optics group at the Laboratory of Chemistry, ENS Lyon, University of Lyon, France (Homepage: http://www.ens‐lyon.fr/CHIMIE). The image shows how complexation of a simple chromophore with boron results in a spectacular improvement of its linear and nonlinear optical properties both in solution and in the solid state. Read the full text of the article at 10.1002/cphc.201600178.
The immunoglobulin‐like superfamily member IGSF3 is a developmentally regulated protein that controls neuronal morphogenesis
Authors: Usardi Alessia , Iyer Keerthana , Sigoillot Séverine M. , Dusonchet Antoine , Selimi Fekrije 
Published: June 2016

ABSTRACTThe establishment of a functional brain depends on the fine regulation and coordination of many processes, including neurogenesis, differentiation, dendritogenesis, axonogenesis, and synaptogenesis. Proteins of the immunoglobulin‐like superfamily (IGSF) are major regulators during this sequence of events. Different members of this class of proteins play nonoverlapping functions at specific developmental time‐points, as shown in particular by studies of the cerebellum. We have identified a member of the little studied EWI subfamily of IGSF, the protein IGSF3, as a membrane protein expressed in a neuron specific‐ and time‐dependent manner during brain development. In the cerebellum, it is transiently found in membranes of differentiating granule cells, and is particularly concentrated at axon terminals. There it co‐localizes with other IGSF proteins with well‐known functions in cerebellar development: TAG‐1 and L1. Functional analysis shows that IGSF3 controls the differentiation of granule cells, more precisely axonal growth and branching. Biochemical experiments demonstrate that, in the developing brain, IGSF3 is in a complex with the tetraspanin TSPAN7, a membrane protein mutated in several forms of X‐linked intellectual disabilities. In cerebellar granule cells, TSPAN7 promotes axonal branching and the size of TSPAN7 clusters is increased by downregulation of IGSF3. Thus IGSF3 is a novel regulator of neuronal morphogenesis that might function through interactions with multiple partners including the tetraspanin TSPAN7. This developmentally regulated protein might thus be at the center of a new signaling pathway controlling brain development. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 75–92, 2017
Morphological changes in hippocampal cytoarchitecture as a function of spatial treatment in birds
Authors: Roth Timothy C. , Stocker Kurtis , Mauck Robert 
Published: June 2016

ABSTRACTMaintaining cognitive processes comes with neurological costs. Thus, enhanced cognition and its underlying neural mechanisms should change in response to environmental pressures. Indeed, recent evidence suggests that variation in spatially based cognitive abilities is reflected in the morphology of the hippocampus (Hp), the region of the brain involved in spatial memory. Moreover, recent work on this region establishes a dynamic link between brain plasticity and cognitive experiences both across populations and within individuals. However, the mechanisms involved in neurological changes as a result of differential space use and the reversibility of such effects are unknown. Using a house sparrow (Passer domesticus) model, we experimentally manipulated the space available to birds, testing the hypothesis that reductions in dendritic branching is associated with reduced Hp volume and that such reductions in volume are reversible. We found that reduced spatial availability associated with captivity had a profound and significant reduction in sparrow hippocampal volumes, which was highly correlated with the total length of dendrites in the region. This result suggests that changes to the dendritic structure of neurons may, in part, explain volumetric reductions in region size associated with captivity. In addition, small changes in available space even within captivity produced significant changes in the spine structure on Hp dendrites. These reductions were reversible following increased spatial opportunities. Overall, these results are consistent with the hypothesis that reductions to the Hp in captivity, often assumed to reflect a deleterious process, may be adaptive and a consequence of the trade‐off between cognitive and energetic demands. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 77: 93–101, 2017
European Society of Cardiology Heart Failure Long‐Term Registry (ESC‐HF‐LT): 1‐year follow‐up outcomes and differences across regions
Authors: Crespo‐Leiro Maria G. , Anker Stefan D. , Maggioni Aldo P. , Coats Andrew J. , Filippatos Gerasimos , Ruschitzka Frank , Ferrari Roberto , Piepoli Massimo Francesco , Delgado Jimenez Juan F. , Metra Marco , Fonseca Candida , Hradec Jaromir , Amir Offer , Logeart Damien , Dahlström Ulf , Merkely Bela , Drozdz Jaroslaw , Goncalvesova Eva , Hassanein Mahmoud , Chioncel Ovidiu , Lainscak Mitja , Seferovic Petar M. , Tousoulis Dimitris , Kavoliuniene Ausra , Fruhwald Friedrich , Fazlibegovic Emir , Temizhan Ahmet , Gatzov Plamen , Erglis Andrejs , Laroche Cécile , Mebazaa Alexandre ,   on behalf of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)
Published: June 2016

AbstractAimsThe European Society of Cardiology Heart Failure Long‐Term Registry (ESC‐HF‐LT‐R) was set up with the aim of describing the clinical epidemiology and the 1‐year outcomes of patients with heart failure (HF) with the added intention of comparing differences between participating countries.Methods and resultsThe ESC‐HF‐LT‐R is a prospective, observational registry contributed to by 211 cardiology centres in 21 European and/or Mediterranean countries, all being member countries of the ESC. Between May 2011 and April 2013 it collected data on 12 440 patients, 40.5% of them hospitalized with acute HF (AHF) and 59.5% outpatients with chronic HF (CHF). The all‐cause 1‐year mortality rate was 23.6% for AHF and 6.4% for CHF. The combined endpoint of mortality or HF hospitalization within 1 year had a rate of 36% for AHF and 14.5% for CHF. All‐cause mortality rates in the different regions ranged from 21.6% to 36.5% in patients with AHF, and from 6.9% to 15.6% in those with CHF. These differences in mortality between regions are thought reflect differences in the characteristics and/or management of these patients.ConclusionThe ESC‐HF‐LT‐R shows that 1‐year all‐cause mortality of patients with AHF is still high while the mortality of CHF is lower. This registry provides the opportunity to evaluate the management and outcomes of patients with HF and identify areas for improvement.
The effect of the belief in free market ideology on redressing corporate injustice
Authors: Kardos Peter , Leidner Bernhard , Zsolnai Laszlo , Castano Emanuele 
Published: June 2016

AbstractMany people in the major Western economies (e.g., United States, UK, and Germany) subscribe to free market ideology (FMI), which claims that institutional oversight of the market is unnecessary for public reaction can force corporations to regulate their own behavior. The question then becomes how people's belief in FMI affects their reactions to corporate transgressions. Given its ingroup‐centered values, we hypothesized that FMI beliefs would bias reactions to corporate transgressions. We report results of a pilot study showing that FMI beliefs are predicted by selfishness, tradition, conformity, and lack of universalism. We then report three experiments, which showed that stronger FMI beliefs predict weaker demands to redress corporate injustices committed by ingroup (but not outgroup) corporations (Studies 1–3), especially when victims of corporate wrongdoings belong to an outgroup (rather than the ingroup; Study 3). The findings inform our conceptual understanding of FMI and give insights about its implications for market justice.
Are we going about chemical risk assessment for the aquatic environment the wrong way?
Authors: Johnson Andrew C. , Sumpter John P. 
Published: June 2016

Abstract

The goal of protecting the aquatic environment through testing thousands of chemicals against hundreds of aquatic species with thousands of endpoints while also considering mixtures is impossible given the present resources. Much of the impetus for studies on micropollutants, such as pharmaceuticals, came from the topic of endocrine disruption in wild fish. But despite concern over reductions in fish fertility, there is little evidence that fish populations are in peril. Indeed, fish biologists suggest that many cyprinid populations have been recovering for the past 30 to 40 yr. The central assumption, key to current risk assessment, that effects observed in the laboratory or predicted by models are readily transferrable to the population level, is therefore questionable. The neglect in monitoring wildlife populations is the key weakness in environmental protection strategies. If we do not know whether aquatic wildlife species are declining or increasing, how valuable are our other ecotoxicological activities? Environ Toxicol Chem 2016;35:1609–1616. © 2016 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC.
Effects of diluted bitumen exposure on juvenile sockeye salmon: From cells to performance
Authors: Alderman Sarah L. , Lin Feng , Farrell Anthony P. , Kennedy Christopher J. , Gillis Todd E. 
Published: June 2016

Abstract

Diluted bitumen (dilbit; the product of oil sands extraction) is transported through freshwater ecosystems critical to Pacific salmon. This is concerning, because crude oil disrupts cardiac development, morphology, and function in embryonic fish, and cardiac impairment in salmon can have major consequences on migratory success and fitness. The sensitivity of early life-stage salmon to dilbit and its specific cardiotoxic effects are unknown. Sockeye salmon parr were exposed to environmentally relevant concentrations of the water-soluble fraction (WSF) of dilbit for 1 wk and 4 wk, followed by an examination of molecular, morphological, and organismal endpoints related to cardiotoxicity. We show that parr are sensitive to WSF of dilbit, with total polycyclic aromatic hydrocarbon (PAH) concentrations of 3.5 µg/L sufficient to induce a liver biomarker of PAH exposure, and total PAH of 16.4 µg/L and 66.7 µg/L inducing PAH biomarkers in the heart. Furthermore, WSF of dilbit induces concentration–dependent cardiac remodeling coincident with performance effects: fish exposed to 66.7 µg/L total PAH have relatively fewer myocytes and more collagen in the compact myocardium and impaired swimming performance at 4 wk, whereas the opposite changes occur in fish exposed to 3.5 µg/L total PAH. The results demonstrate cardiac sensitivity to dilbit exposure that could directly impact sockeye migratory success. Environ Toxicol Chem 2017;36:354–360. © 2016 SETAC
FARVATX: Family‐Based Rare Variant Association Test for X‐Linked Genes
Authors: Choi Sungkyoung , Lee Sungyoung , Qiao Dandi , Hardin Megan , Cho Michael H. , Silverman Edwin K , Park Taesung , Won Sungho 
Published: June 2016

ABSTRACTAlthough the X chromosome has many genes that are functionally related to human diseases, the complicated biological properties of the X chromosome have prevented efficient genetic association analyses, and only a few significantly associated X‐linked variants have been reported for complex traits. For instance, dosage compensation of X‐linked genes is often achieved via the inactivation of one allele in each X‐linked variant in females; however, some X‐linked variants can escape this X chromosome inactivation. Efficient genetic analyses cannot be conducted without prior knowledge about the gene expression process of X‐linked variants, and misspecified information can lead to power loss. In this report, we propose new statistical methods for rare X‐linked variant genetic association analysis of dichotomous phenotypes with family‐based samples. The proposed methods are computationally efficient and can complete X‐linked analyses within a few hours. Simulation studies demonstrate the statistical efficiency of the proposed methods, which were then applied to rare‐variant association analysis of the X chromosome in chronic obstructive pulmonary disease. Some promising significant X‐linked genes were identified, illustrating the practical importance of the proposed methods.
Incarcerated Sex Offenders in Rehabilitation Account for their Offending
Authors: Geiger Brenda , Fischer Michael 
Published: June 2016

AbstractThis research examines the accounts of 10 out of 22 incarcerated sex offenders undergoing therapy in one of the prison‐based sex‐offender rehabilitation units in Israel and their ability to renegotiate reality to reject stigmatisation and maintain a favourable identity. The research participants had been convicted either of child molestation or of date/statutory rape against an acquaintance. This differentiation was maintained when analysing the individual interviews conducted in prison. Prior to the provision of accounts, to establish the soundness of their character, the interviewees resituated themselves within a normative background in terms of setting, routine activities, and interactions preceding and following the offence. Offenders convicted of child molestation attributed their behaviour to a sudden unpredictable shift in the setting and interactions with the child that resulted in an erection and consequent impulsive sexual behaviour of which they could not be held responsible. Offenders convicted of date/statutory rape admitted responsibility for their action, yet minimised its harm by attributing it to the dynamic chain of interactions with the victim whose behaviour had deviated from the ‘good’ girl or ‘macho’ man on a date and thus had precipitated the act. Rather than discounting sex offenders' accounts as cognitive distortions of a sick mind, prevention and education programme are to rely on such accounts to increase youth and young adult awareness to traditional gender‐role schemata and dating scripts espoused by Israeli macho men that facilitate date rape and to the dynamics of interactional and situational factors placing young children at risk of sexual victimisation. Copyright © 2016 John Wiley & Sons, Ltd.
The nematode stoma: Homology of cell architecture with improved understanding by confocal microscopy of labeled cell boundaries
Authors: Jay Burr A. H. , Baldwin James G. 
Published: June 2016

ABSTRACTNematode stomas vary widely in the cuticular structures evolved for different feeding strategies, yet the arrangement of the epithelial cell classes that form these structures may be conserved. This article addresses several issues that have impeded the full acceptance of this hypothesis including controversies arising from the structure of the Caenorhabditis elegans stoma. We investigated fluorescent antibody labeling of cell boundaries in conjunction with confocal microscopy as an alternative to transmission electron microscopy (TEM), using MH27 to label apical junctions in C. elegans and two other species. Accurately spaced optical sections collected by the confocal microscope provide a three‐dimensional array of pixels (voxels) that, using image‐processing software, can be rotated and sectioned at accurately chosen thicknesses and locations. Ribbons of fluorescence clearly identify cell boundaries along the luminal cuticle in C. elegans and Zeldia punctata and less clearly in Bunonema sp. The patterns render cell classes and their relationships readily identifiable. In the C. elegans stoma they correct a misreading of serial TEMs that was not congruent with architecture in other nematodes—the row of marginal cells is now seen to be continuous as in other nematodes, rather than being interrupted by encircling pm1 cells. Also impeding understanding, the reference to certain cell classes as ‘epithelial’ and others as “muscle” in the C. elegans literature is at variance with muscle expression in most other taxa. For consistent comparison among species, we propose that these cell class descriptors based on function be replaced by topological terms. With these and other confusing concepts and terminology removed, the homology of the cellular architecture among taxa becomes obvious. We provide a corrected description of the cell architecture of the C. elegans stoma and examples of how it is modified in other taxa with different feeding strategies. J. Morphol. 277:1168–1186, 2016. © 2016 Wiley Periodicals, Inc.
The locomotion of Babakotia radofilai inferred from epiphyseal and diaphyseal morphology of the humerus and femur
Authors: Marchi Damiano , Ruff Christopher B. , Capobianco Alessio , Rafferty Katherine L. , Habib Michael B. , Patel Biren A. 
Published: June 2016

ABSTRACTPalaeopropithecids, or “sloth lemurs,” are a diverse clade of large‐bodied Malagasy subfossil primates characterized by their inferred suspensory positional behavior. The most recently discovered genus of the palaeopropithecids is Babakotia, and it has been described as more arboreal than Mesopropithecus, but less than Palaeopropithecus. In this article, the within‐bone and between‐bones articular and cross‐sectional diaphyseal proportions of the humerus and femur of Babakotia were compared to extant lemurs, Mesopropithecus and Palaeopropithecus in order to further understand its arboreal adaptations. Additionally, a sample of apes and sloths (Choloepus and Bradypus) are included as functional outgroups composed of suspensory adapted primates and non‐primates. Results show that Babakotia and Mesopropithecus both have high humeral/femoral shaft strength proportions, similar to extant great apes and sloths and indicative of forelimb suspensory behavior, with Babakotia more extreme in this regard. All three subfossil taxa have relatively large femoral heads, also associated with suspension in modern taxa. However, Babakotia and Mesopropithecus (but not Palaeopropithecus) have relatively small femoral head surface area to shaft strength proportions suggesting that hind‐limb positioning in these taxa during climbing and other behaviors was different than in extant great apes, involving less mobility. Knee and humeral articular dimensions relative to shaft strengths are small in Babakotia and Mesopropithecus, similar to those found in modern sloths and divergent from those in extant great apes and lemurs, suggesting more sloth‐like use of these joints during locomotion. Mesopropithecus and Babakotia are more similar to Choloepus in humerofemoral head and length proportions while Palaeopropithecus is more similar to Bradypus. These results provide further evidence of the suspensory adaptations of Babakotia and further highlight similarities to both extant suspensory primates and non‐primate slow arboreal climbers and hangers. J. Morphol. 277:1199–1218, 2016. © 2016 Wiley Periodicals, Inc.
Effects of Curcuma longa rhizome powder on egg quality, performance and some physiological indices of laying hens fed different levels of metabolizable energy
Authors: Mirbod Mahsa , Mahdavi Amir Hossein , Samie Abdol‐Hossein , Mehri Mehran 
Published: June 2016

AbstractBACKGROUNDHigh‐energy diets of laying hens may improve roductive performance, although some negative effects may also appear with respect to egg quality and physiological parameters. Curcuma longa rhizome powder (CRP) has beneficial effects on health indices of the birds through antioxidant and antimicrobial properties, especially when the birds experience nutritional stress.RESULTSIncreasing dietary CRP enhanced egg quality by improving eggshell thickness and hardness but decreasing yolk cholesterol content (P < 0.05). The best feed conversion ratio was obtained in birds fed high‐apparent metabolizable energy (AME) diets supplemented with 2.0 g kg−1 CRP (P < 0.05). Although increasing dietary AME elevated the serum concentration of triglycerides (P < 0.05) and enzymatic activities of alanine aminotransferase and aspartate aminotransferase (P < 0.05), dietary inclusion of CRP alleviates the blood levels of these enzymes (P < 0.01). Low level of dietary CRP boosted the immune responses to Newcastle virus (P < 0.01) and sheep red blood cells (P < 0.05) antigens but decreased the heterophil to lymphocyte ratio (P < 0.05). Inclusion of at least 2.0 g kg−1 CRP in the diet of laying decreased Escherichia coli enumerations in the ileal content (P < 0.01) and improved villus height, crypt depth and goblet cell numbers (P < 0.05).CONCLUSIONAn improvement in the productive performance of laying hens fed high‐energy diets might be associated with decreasing health indices and product quality, which could potentially be amended by nutritional modifications such as incorporating medicinal herbs in the feed. © 2016 Society of Chemical Industry
Spatio‐temporal variability of methane (CH4) concentrations and diffusive fluxes from a tropical coastal embayment surrounded by a large urban area (Guanabara Bay, Rio de Janeiro, Brazil)
Authors: Cotovicz Luiz C. , Knoppers Bastiaan A. , Brandini Nilva , Poirier Dominique , Costa Santos Suzan J. , Abril Gwenaël 
Published: June 2016

AbstractThe increasing concentrations of methane (CH4) in the atmosphere stress the importance of monitoring and quantifying the fluxes from coastal environments. In nine sampling campaigns between 2013 and 2014, we measured the spatial CH4 concentrations, identified major sources and calculated the fluxes at the air‐water interface in an eutrophic tropical embayment, Guanabara Bay, Rio de Janeiro, Brazil. The bay presented high spatial variability of CH4 concentrations, without a significant trend with salinity, but observed the influence of the urban areas at its watershed. Although the more polluted sector of the bay accounts for about 10% of the sampled surface area, it contributed to one half of the bay's total CH4 emissions. In most cases, high CH4 concentrations seemed be sustained by allochtonous sources such as the sewage network and polluted rivers, especially under high accumulated precipitation conditions. In the most stratified area, at the inner and centre of the Bay, CH4 concentrations were not significantly higher in bottom hypoxic waters than in surface waters, suggesting that CH4 diffusion from these sediments was modest, due to the prevalence of sulphate reduction over methanogenesis. Our calculated annual air‐sea fluxes (565–980 μmol m−2 d−1) are well above those of most estuaries worldwide, showing that urban pollution can be an important source of CH4 to the coastal waters and even more significant than the presence of organic‐rich environments, like salt marshes and mangroves. Comparing the greenhouse gas emissions in terms of CO2‐equivalent, CH4 emissions reduced the net CO2 sink in Guanabara Bay by 16%.