bluuebunny/crossref_metadata_2025_split huggingface dataset:
Causes of Mortality in Older People With Intellectual Disability: Results From the HA-ID Study
Authors: Oppewal Alyt , Schoufour Josje D. , van der Maarl Hanne J.K. , Evenhuis Heleen M. , Hilgenkamp Thessa I.M. , Festen Dederieke A. 
Published: December 2017

AbstractWe aim to provide insight into the cause-specific mortality of older adults with intellectual disability (ID), with and without Down syndrome (DS), and compare this to the general population. Immediate and primary cause of death were collected through medical files of 1,050 older adults with ID, 5 years after the start of the Healthy Ageing and Intellectual Disabilities (HA-ID) study. During the follow-up period, 207 (19.7%) participants died, of whom 54 (26.1%) had DS. Respiratory failure was the most common immediate cause of death (43.4%), followed by dehydration/malnutrition (20.8%), and cardiovascular diseases (9.4%). In adults with DS, the most common cause was respiratory disease (73.3%), infectious and bacterial diseases (4.4%), and diseases of the digestive system (4.4%). Diseases of the respiratory system also formed the largest group of primary causes of death (32.1%; 80.4% was due to pneumonia), followed by neoplasms (17.6%), and diseases of the circulatory system (8.2%). In adults with DS, the main primary cause was also respiratory diseases (51.1%), followed by dementia (22.2%).
Multimorbidity and Polypharmacy Are Independently Associated With Mortality in Older People With Intellectual Disabilities: A 5-Year Follow-Up From the HA-ID Study
Authors: Schoufour Josje D. , Oppewal Alyt , van der Maarl Hanne J.K. , Hermans Heidi , Evenhuis Heleen M. , Hilgenkamp Thessa I.M. , Festen Dederieke A. 
Published: December 2017

Abstract
We studied the association between multimorbidity, polypharmacy, and mortality in 1,050 older adults (50+) with intellectual disability (ID). Multimorbidity (presence of ≥ 4 chronic health conditions) and polypharmacy (presence ≥ 5 chronic medication prescriptions) were collected at baseline. Multimorbidity included a wide range of disorders, including hearing impairment, thyroid dysfunction, autism, and cancer. Mortality data were collected during a 5-year follow-up period. Cox proportional hazards models were used to determine the independent association between multimorbidity and polypharmacy with survival. Models were adjusted for age, sex, level of ID, and the presence of Down syndrome. We observed that people classified as having multimorbidity or polypharmacy at baseline were 2.60 (95% CI = 1.86–3.66) and 2.32 (95% CI = 1.70–3.16) times more likely to decease during the follow-up period, respectively, independent of age, sex, level of ID, and the presence of Down syndrome. Although slightly attenuated, we found similar hazard ratios if the model for multimorbidity was adjusted for polypharmacy and vice versa. We showed for the first time that multimorbidity and polypharmacy are strong predictors for mortality in people with ID. Awareness and screening of these conditions is important to start existing treatments as soon as possible. Future research is required to develop interventions for older people with ID, aiming to reduce the incidence of polypharmacy and multimorbidity.
Mapping the Contexts of Contemporary Curating: The Visual Arts Exhibitionary Complex
Authors: Smith Terry 
Published: December 2017

Abstract
In cities throughout the world, the Visual Arts Exhibitionary Complex (VAEC) is a constellation of exhibitionary venues that ranges from metropolitan museums to pop-up installations and Internet postings. This article maps VAECs as historical developments, as power hierarchies, and as consisting of distinct but internally dynamic elements that interact with each other constantly. VAECs are the primary contexts in which curating is done today, so this article also presents a series of charts that outline the historical evolution and the current forms of professional categorization within curating: types of exhibition, display formats, curatorial styles, projective publics and modes of collaboration.
The Curatorial and Its Mediation
Authors: Möntmann Nina 
Published: December 2017

Abstract
This article examines recent exhibitions that serve as examples of the curatorial as a transdisciplinary method to activate and intervene in real-life contexts. These projects, organized by a diverse range of collectives and curators, mobilize domestic, urban and political zones in order to encourage participation in systemic social transformation. Here the notion of curatorial mediation is extended to the production of public discourse around specific topics, such as the black market or artistic censorship. The central task for curating today, then, involves intersecting with conflicts in various social and economic sectors and integrating them into processes of construction. By researching and engaging beyond the margins of the conventional cultural field, curators can critically investigate pressing concerns and seek out new methodologies to effect social change.
Intoxicacion por olanzapina en una adolescente
Authors: Farías Curtidor Luis Enrique , Blanco Caviedes Ginna Charlotte , Aguilar Mejía Javier Alfonso 
Published: December 2017

Antecedentes: Los antipsicóticos atípicos han reemplazado a los agentes tradicionales por su menor proporción de efectos extrapiramidales. Las intoxicaciones y sobredosis relacionadas con estos medicamentos son un problema importante en países industrializados y no industrializados.
Resumen del caso: Adolescente femenina de 15 años de edad quien ingresó a la clínica por presentar alteración del estado de conciencia y movimientos anormales, sin antecedente inicial de ingesta de medicamentos. Los laboratorios iniciales evidenciaron alcalosis metabólica e hipocalemia leve, con resultados positivos para fenobarbital en un examen inicial toxicológico de orina y resultados negativos en un control posterior. Fue trasladada a la unidad de cuidados intermedios en donde persistió con alteración del estado de conciencia, fiebre constante y taquicardia. Debido a la falta de claridad respecto al cuadro clínico, se realizó una punción lumbar con resultados normales. Luego de interrogar una segunda vez a la familia, se documentó una ingesta de 52 tabletas de olanzapina antes del ingreso. Se sospechó síndrome neuroléptico maligno, los estudios posteriores fueron normales. La paciente evolucionó favorablemente. Luego de una valoración psiquiátrica, se decidió hacer seguimiento ambulatorio.
Conclusión: Ante la presencia de alteración del estado de conciencia, es importante considerar la posibilidad de intoxicación dentro del diagnóstico diferencial.
EFFECT OF PRIMING ON GERMINATION AND INITIAL GROWTH OF MELON PLANTS UNDER SALT STRESS
Authors: CASTAÑARES J. L. , BOUZO C. A. 
Published: December 2017

The objective of this work was to evaluate the effect of different osmotic agents and priming durations on the germination and initial growth of melon in salinity. The osmotic agents were NaCl and CaCl 2 and durations 2 and 4 days. First a response curve of germination to salinity was made. After priming the seeds were placed to germinate in a saline medium (14 dS m -1 ). The germination percentage was determined. The two treatments with the best results (NaCl and CaCl 2 2 days in both salts) were selected to evaluate the initial growth of the plants in salinity. It was sown in pots, irrigated with nutrient solution and 60 mM NaCl. The germination was reduced to 50% with 14 dS m -1 and inhibited with 22 dS m -1 . The best germination was achieved with NaCl and CaCl 2 2 days with 99 and 94% respectively. Both treatments showed an increase in growth parameters and chlorophyll content.
LA ORGANIZACION DE PRODUCTORES FAMILIARES EN LAS FERIAS FRANCAS DE LA PROVINCIA DE CÓRDOBA
Authors: FERRER G. , BARRIENTOS M. , SAAL G. 
Published: December 2017

El objetivo de este artículo es comprender los procesos organizativos de 12 ferias francas de la provincia de Córdoba. Para ello se realizaron entrevistas a actores clave durante los años 2014 y 2015. Si bien las ferias francas son valoradas inicialmente como una solución apropiada tanto para los consumidores conscientes, como para los roductores familiares que buscan una alternativa de comercialización más sustentable, el análisis revela que las mismas son un campo social tensionado por relaciones de colaboración/competencia entre diversos actores que interactúan en el territorio. Los resultados permiten identifi car dos tendencias en disputa en la mayoría de los feriantes: i) la asamblearia, que sostiene una posición individualista y confía en la regulación del proceso que realizan los consumidores y; ii) la formalizante, que propicia la organización en comisiones internas que acuerden normas para el comportamiento de los feriantes.
TAMBEROS DE LA CUENCA LECHERA CENTRAL SANTAFESINA. ¿PRODUCTOR ASOCIADO O MANO DE OBRA?
Authors: SANDOVAL P. S. M. , LEONARDI R. , PERNUZZI C. , ALANDA G. , BENITEZ R. , ARNAUDO J. P. , BRANCE BONVINI M. I. , ACOSTA G. , EGGEL A. , MARTINS L. 
Published: December 2017

El proceso de modernización del agro de las dos últimas décadas, incide directamente en un sujeto social de la cuenca lechera santafesina. 1990 genera nueva legislación que enmarca el trabajo y la vida del tambero y su familia, reconfi gurando este sujeto social fundamental. La metodología cualitativa utilizada fue Estudio de Caso sobre el Departamento las Colonias. Los resultados presentados en este artículo demuestran que los cambios ocurridos por la nueva fi gura legal del tambero, impactan en sus condiciones de vida. A pesar que la nueva legislación convierte al empleado tambero en productor asociado, no provoca mejoras en su situación socioeconómica. El trabajo completo es un proceso de articulación entre actividad científi ca y desarrollo rural, donde se identificaron y sistematizaron los contextos de ambas situaciones legales y los cambios en las condiciones de vida del tambero y su familia, suministrando conocimientos para orientar la tarea de extensión relacionada al desarrollo rural.
District Central Libraries in Rayalaseema Region of Andhra Pradesh: A Study
Authors: Raghavaiah Parvathaneni , Babu K. Surendra 
Published: December 2017

This paper focuses on the functioning, library resources, services, and problems existing in the District Central Libraries of Rayalaseema region of Andhra Pradesh. A survey was conducted using questionnaire tool for collecting data from the librarians of the District Central Libraries (DCL) regarding collection development, sources of grants, manpower, library services, physical and ICT infrastructural facilities, etc. The study reveals that majority of the libraries are possessing the collection in the range of 40,000 to 50,000. Further, it is also found that lack of staff, ICT facilities, lack of sufficient budget are the main problems faced by these libraries in Rayalaseema region.
Citation Analysis of Business Research: An International Journal in the Field of Business
Authors: Fatima Nishat 
Published: December 2017

<p>The present study is citation analysis of Business Research. It covers 18 issues of 9 volumes of Business Research published bi-annually during the period 2008-2016. The analysis covers the study of citation pattern and chronological growth citations. It also covers authorship pattern of the articles and various information sources of cited material. On the basis of citation analysis, a rank list of journals is prepared and core journals in the field of Business research are identified. Similarly, core areas of research are identified. The study reveals that researchers have cited journals (77.33%) more than books, editorial works and all other sources of information. Growth in collaborative trend of writing papers is also noticed as citations contributed by two authors is (37.67%) and single authors is (33.42%) followed by three authors (21.59%). Half-life of journal’s citations is found to be fourteen years. Bradford’s law doesn’t found fit in the study. Academy of Management Journal (157 citations), Strategic Management Journal (141 citations) and The Journal of Finance (136 citations) are the most cited journals. Supply chain management and advertising are the two main areas of research among researchers.</p>
Asociaciones científicas y academia de ciencias de Cuba: sinergias para el desarrollo
Authors: Perera López Danays Damarys , Saladrigas Medina Hilda , Leyva Maestre Yailuma , Linares Herrera Manuel Paulino 
Published: December 2017

Las asociaciones científicas junto a otras organizaciones: universidades, empresas que desarrollan investigación, administraciones públicas, museos, están creando un gigantesco espacio de aprendizaje y comunicación de la ciencia. Las academias y las asociaciones científicas, a nivel mundial, ofrecen un marco particularmente apropiado para la presentación y debate de las responsabilidades sociales de esas comunidades. Los impactos de sus acciones de comunicación y divulgación científica, corroboran el alcance que pudieran tener en el desarrollo de una cultura científica, pero construyendo estos saberes con un enfoque integrador. La falta de diálogo entre distintos saberes, tópico ampliamente abordado en la literatura especializada, no se da, únicamente, entre los “saberes académicos” y los “saberes populares”, sino en las relaciones entre aquellas organizaciones que producen comunicación científica.Esta problemática está presente en las interacciones comunicativas que se desarrollan entre las asociaciones científicas, atendidas por la Academia de Ciencias de Cuba. Realizar un primer diagnóstico y presentar una propuesta de solución a esta problemática, a partir de las herramientas que brinda la disciplina de la comunicación, es el objetivo de la propuesta investigativa. Asociaciones científicas: diálogo de saberes para el desarrollo, investigación que se desarrolla en la XIV Edición de la Maestría en Ciencias de la Comunicación. Se presentan resultados de la investigación.
Mixed Neurodevelopmental and Neurodegenerative Pathology inNhe6-Null Mouse Model of Christianson Syndrome
Authors: Xu Meiyu , Ouyang Qing , Gong Jingyi , Pescosolido Matthew F. , Pruett Brandon S. , Mishra Sasmita , Schmidt Michael , Jones Richard N. , Gamsiz Uzun Ece D. , Lizarraga Sofia B. , Morrow Eric M. 
Published: December 2017

AbstractChristianson syndrome (CS) is an X-linked disorder resulting from loss-of-function mutations inSLC9A6, which encodes the endosomal Na+/H+exchanger 6 (NHE6). Symptoms include early developmental delay, seizures, intellectual disability, nonverbal status, autistic features, postnatal microcephaly, and progressive ataxia. Neuronal development is impaired in CS, involving defects in neuronal arborization and synaptogenesis, likely underlying diminished brain growth postnatally. In addition to neurodevelopmental defects, some reports have supported neurodegenerative pathology in CS with age. The objective of this study was to determine the nature of progressive changes in the postnatal brain inNhe6-null mice. We examined the trajectories of brain growth and atrophy in mutant mice from birth until very old age (2 yr). We report trajectories of volume changes in the mutant that likely reflect both brain undergrowth as well as tissue loss. Reductions in volume are first apparent at 2 mo, particularly in the cerebellum, which demonstrates progressive loss of Purkinje cells (PCs). We report PC loss in two distinctNhe6-null mouse models. More widespread reductions in tissue volumes, namely, in the hippocampus, striatum, and cortex, become apparent after 2 mo, largely reflecting delays in growth with more limited tissue losses with aging. Also, we identify pronounced glial responses, particularly in major fiber tracts such as the corpus callosum, where the density of activated astrocytes and microglia are substantially increased. The prominence of the glial response in axonal tracts suggests a primary axonopathy. Importantly, therefore, our data support both neurodevelopmental and degenerative mechanisms in the pathobiology of CS.
Feeder Approach between Trials Is Increased by Uncertainty and Affects Subsequent Choices
Authors: Gruber Aaron J. , Thapa Rajat , Randolph Sienna H. 
Published: December 2017

AbstractAnimals quickly learn to approach sources of food. Here, we report on a form of approach in which rats made volitional orofacial contact with inactive feeders between trials of a self-paced operant task. This extraneous feeder sampling (EFS) was never reinforced and therefore imposed an opportunity and effort cost. EFS decreased during initial training but persisted thereafter. The relative rate of EFS to operant responding increased with novel changes to the operant chamber, reward devaluation by prefeeding, or lesions to the dorsolateral striatum. We speculate that this may function to increase exploration when the task is uncertain (early in learning or introduction of novel apparatus components), when the opportunity cost is low, or when the learned sensorimotor solution is compromised. Moreover, EFS strongly affected subsequent choices by triggering a lose-shift response away from the sampled feeder, even though it occurred outside of the trial context. This indicates that at least some behaviors occurring between trials impact future behaviors and should be considered in decision-making studies.
Legionnaires’ disease as an occupational risk related to decontamination work after the Fukushima nuclear disaster: A case report
Authors: Sawano Toyoaki , Tsubokura Masaharu , Ozaki Akihiko , Leppold Claire , Kato Shigeaki , Kambe Toshiyuki 
Published: December 2017

Abstract

Objectives
Legionnaires’ disease (LD), which is atypical pneumonia with a broad variety of clinical symptoms, can lead to death despite its low incidence. There are multiple risk factors for LD, yet little information is available concerning what kind of environmental factors are linked to higher risk of LD development. We have experienced a fatal case of LD, which occurred in a decontamination worker after the Fukushima nuclear disaster.

Case
A 53-year-old Japanese male visited our hospital with symptoms of fever, vomiting, diarrhea, and altered mental status, but not with respiratory manifestations. He was engaged in decontamination work, which generally includes operations such as the removal of topsoil in mountainous areas and cleaning roads and roofs of residential buildings with highpressure water. He was required to wear specific equipment to prevent radiation exposure, and lived in a workers’ dormitory or shared house, thereby sharing spaces with other workers. Normal antibiotic therapy did not improve his symptoms following his diagnosis with pneumonia. A urinary antigen detection test was then conducted, leading to a diagnosis of LD. Despite the change of antibiotic to levofloxacin, multiple organ failure led to his death.

Conclusion
Decontamination workers may be at a high risk for developing LD and living and working conditions among them are possible contributors.
Cross-sectional Internet-based survey of Japanese permanent daytime workers’ sleep and daily rest periods
Authors: Ikeda Hiroki , Kubo Tomohide , Sasaki Takeshi , Liu Xinxin , Matsuo Tomoaki , So Rina , Matsumoto Shun , Yamauchi Takashi , Takahashi Masaya 
Published: December 2017

Abstract

Objectives
This study aimed to describe the sleep quantity, sleep quality, and daily rest periods (DRPs) of Japanese permanent daytime workers.

Methods
Information about the usual DRP, sleep quantity, and sleep quality (Japanese version of the Pittsburgh Sleep Quality Index: PSQI-J) of 3,867 permanent daytime workers in Japan was gathered through an Internet-based survey. This information was analyzed and divided into the following eight DRP groups: &lt;10, 10, 11, 12, 13, 14, 15, and ≥ 16 h.

Results
The sleep durations for workers in the &lt;10, 10, 11, 12, 13, 14, 15, and ≥ 16 h DRP groups were found to be 5.3, 5.9, 6.1, 6.3, 6.5, 6.7, 6.7, and 6.9 h, respectively. The trend analysis revealed a significant linear trend as the shorter the DRP, the shorter was the sleep duration. The PSQI-J scores for the &lt;10, 10, 11, 12, 13, 14, 15, and ≥ 16 h DRP groups were 7.1, 6.7, 6.7, 6.3, 6.0 (5.999), 5.6, 5.2, and 5.2, respectively. The trend analysis revealed a significant linear trend as the shorter the DRP, the lower was the sleep quality.

Conclusions
This study described sleep quantity, sleep quality, and DRP in Japanese daytime workers. It was found that a shorter DRP was associated with poorer sleep quantity as well as quality.
Understanding the administrative regulation on occupational health and trend in China
Authors: Zhou Zhijun 
Published: December 2017

Abstract
With the immense economic growth and social development, China has gained worldwide attention. With the quick growth of industrialization, several international professionals are gaining interest in occupational management system and in the role of the Chinese Government in protecting the worker’s health. The Law on Prevention and Control of Occupational Diseases and the Work Safety Law are the two most important laws in China, which highlight the responsibilities of the employer, employee, governmental agencies, authorized occupational health service agency, and other stakeholders. The State Council comprises two departments, namely, the State Administration on Work Safety (SAWS) and the National Health and Family Planning Commission (NHFPC), which are responsible for governing the occupational health work. A series of regulations and standards have been promulgated by the Chinese Government to encourage or instruct the employers to fulfill their responsibility; however, several issues persist related to occupational health work, including administrative, technological, and sociocultural aspects. At present, the Chinese Government wants to enhance the reform in both economic and administrative structures, and the adjustments for modifying and / or improving the occupational health regulatory system are expected. Notably, the occupational health work in China must be altered for better.
Evaluation of the optic nerve head and peripapillary retinal nerve fiber layer thickness in patients receiving Electro-Convulsive Therapy
Authors: Shahraki Kourosh , Khosravi Alireza , Kaffashipour Shiva , Shahraki Kianoush , Sadeghi Masoud 
Published: December 2017

Background: Electroconvulsive therapy (ECT) is a method commonly used in the treatment of psychiatric disorders. As ocular side effects from OCT are less studied and discussed, the aim of this study was to evaluate the profile of the peripapillary retinal nerve fiber layer thickness in patients receiving ECT.
Method: This study was performed on 30 patients who had indication for ECT. After recording demographic data, retinal nerve fiber layer thickness was measured by using spectral domain optical coherence tomography (Heidelberg Engineering, Heidelberg, Germany) of optic nerve head and peripapillary retinal nerve fiber layer.
Results: Our results showed that for most of the studied variables, the normal range was observed in less than 85% of patients receiving ECT. Variables which were outside the normal range were: cup disk (C/D) ratio (right and left eyes were 50% and 46.7%, respectively), vertical C/D ratio (right and left eyes were 53.3% and 46.7%, respectively), and cup volume (right and left eyes were 53.3% and 33.3%, respectively).
Conclusion: This study showed that a high percentage of patients receiving ECT had changes in the optic nerve head while intra-ocular pressure in these patients was normal. It is warranted for examiners to pay attention to diagnosis of normal tension glaucoma in patients receiving ECT.