bluuebunny/crossref_metadata_2025_split huggingface dataset:
La Enseñanza de la Lengua Española en la Academia Militar das Agulhas Negras
Authors: COSTA DUARTE ANDRE FRANGULIS , Santos Maria Eugênia Lobato dos 
Published: October 2024

Este artículo tiene como finalidad presentar un panorama sobre la enseñanza de Lengua Española en la Academia Militar das Agulhas Negras (AMAN). Se expone, inicialmente, una justificativa para la enseñanza de este idioma en este establecimiento de enseñanza, acompañado de su histórico durante las últimas décadas. A continuación, se presentan las actividades realizadas por la Cátedra de Español, la documentación curricular específica de este idioma y los aspectos del Proyecto Idiomas – “CertificAMAN” pertinentes. La elaboración de este trabajo se valió del abordaje cualitativo, a partir de datos obtenidos por un estudio de campo que tuvo como enfoque la comunidad de trabajo formada por los profesores de Español. Una de las conclusiones es que la evolución de la enseñanza de esta lengua extranjera ocurre en sintonía con la propia evolución de la enseñanza militar y con las expectativas de la Fuerza Terrestre en la competencia lingüística de sus oficiales.
La solidarité totale. Avenir cosmopolitique de la solidarité et solidarisme écologique
Authors: Messerschmidt-Mariet Quentin 
Published: October 2024

La réduction de la solidarité à des domaines dédiés, comme les politiques sociales ou la charité, empêche de bien saisir la richesse de la théorie solidariste établie par Léon Bourgeois à la fin du XIXe siècle. Pourtant, le solidarisme portait déjà en germe une vision écologique, une « solidarité cosmique », qui ne peut qu’aider à mieux répondre à la crise environnementale actuelle. En mobilisant une vision de la doctrine cosmopolitique, cet article cherche à montrer en quoi les outils du solidarisme, comme la loi de l’interdépendance réciproque, la dette sociale et le quasi-contrat, peuvent s’actualiser pour fonder un solidarisme écologique et une solidarité totale.
La producción fluida. El almacén como forma logística en la nueva era industrial
Authors: Benvegnù Carlotta , Gaborieau David 
Published: October 2024

El sector logístico agrupa actualmente en torno a 900 000 empleos e Francia, en su mayor parte, trabajos obreros. Ha crecido considerablemente desde 1980, entonces suponía el 8% del conjunto de empleos, hoy se eleva al 13 %. Lejos de desaparecer, el trabajo industrial se ha desplazado a otras ramas más allá de la industria como es el sector logístico. En este artículo, abordaremos primeramente una caracterización de este sector y, a través dos estudios de caso analizaremos el proceso de transformación del sector logístico y de sus principales espacios productivos. Describiremos el proceso mediante el cual la logística se extiende al mundo industrial convertida en «fábrica de paquetes».
Compatibility of Most Efficient Rhizobium Strain with Different Seed Dressing Fungicides in Mung Bean Crop
Authors: Pawar V. R. , Sontakke P. L. , Sarode S. B. , Kale H. P. 
Published: October 2024

Symbiotic nitrogen fixation is considered as an important source of nitrogen on earth. Numerous leguminouscrop fix about 200 – 300 kg N/ha.Some microorganisms especially bacteria are able to colonise and fix nitrogen biologically in the soil through symbiotic process. A pot culture experiment was conducted to examine the compatibility of Rhizobium with nine fungicides and their combination used for seed treatment. The combination effects of inoculation with fungicide growth and number of nodules, dry weight of nodules, dry matter parameters etc. were studied. The seed treatment of mungbean seed with copper oxychloride was found most effective among all the seed treatments. Seed treatment with different seed dressing fungicide had no adverse effect on germination, nodulation, yield-attributing characters and grain yield when applied alone or in combination with Rhizobium inoculant, thus, indicating the compatibility amongst all the two components, viz. fungicide and Rhizobium inoculant for seed treatment in (mungbean). Laboratory studies have also shown fungicides containing high levels of metalaxyl or metalaxyl-M have an inhibitory effect on rhizobia and nodulation, and so applying a granular inoculant or liquid or slurry inoculant in furrow is recommended when these fungicides are applied to seed. Treating seed with fungicide before sowing is a common method of protecting seedlings from fungal pathogens. While some fungicides are toxic to rhizobia, if these toxic effects are avoided, seed applied fungicides can increase plant health and root growth which in turn can benefit nodulation and N fixation. However, where the inoculants applied to seed come in direct contact with the fungicide, toxicity issues can occur.Compatibility
An Analysis of Millets in Odisha and Madhya Pradesh, India: A Comparative Study
Authors: Rajput Ankita , Chaturvedi Poonam , Dubey Priyanka Mishra , Mishra Iti Gontia 
Published: October 2024

The study examined the growth in area, production and yield of millets in Odisha and Madhya Pradesh, India. The data for the study was obtained from the website of indiastat.com. The crops selected were bajra, jowar, ragi and small millets. The data on area, production and productivity were collected from 2000-01 to 2020-21. The analytical tools used in the study are compound growth rate and coefficient of variation. The results showed that millet area had been declining over time but the production has increased. Area and production of bajra was declining in Odisha, it was increasing in Madhya Pradesh. Jowar’s area and production are declining in both states but the yield is increasing. In terms of yield, ragi exhibited the highest variability in Odisha, whereas in Madhya Pradesh, the highest variability was observed in the area and production of ragi. Odisha showed the highest growth rate in the yield of bajra, while in Madhya Pradesh, the highest growth rate was observed in the yield of small millets. Millets consumption needs to be promoted among people who require gluten-free fiber rich diet, and wants to consume organic products for health benefits. The promotion of organic farming in millets by state governments should be encouraged, considering its inherent resistance to a wide range of pests and diseases.
Coupled mesoscale‐LES modeling of a diurnal cycle during the CWEX‐13 field campaign: From weather to boundary‐layer eddies
Authors: Muñoz‐Esparza Domingo , Lundquist Julie K. , Sauer Jeremy A. , Kosović Branko , Linn Rodman R. 
Published: April 2017

AbstractMultiscale modeling of a diurnal cycle of real‐world conditions is presented for the first time, validated using data from the CWEX‐13 field experiment. Dynamical downscaling from synoptic‐scale down to resolved three‐dimensional eddies in the atmospheric boundary layer (ABL) was performed, spanning 4 orders of magnitude in horizontal grid resolution: from 111 km down to 8.2 m (30 m) in stable (convective) conditions. Computationally efficient mesoscale‐to‐microscale transition was made possible by the generalized cell perturbation method with time‐varying parameters derived from mesoscale forcing conditions, which substantially reduced the fetch to achieve fully developed turbulence. In addition, careful design of the simulations was made to inhibit the presence of under‐resolved convection at convection‐resolving mesoscale resolution and to ensure proper turbulence representation in stably‐stratified conditions. Comparison to in situ wind‐profiling lidar and near‐surface sonic anemometer measurements demonstrated the ability to reproduce the ABL structure throughout the entire diurnal cycle with a high degree of fidelity. The multiscale simulations exhibit realistic atmospheric features such as convective rolls and global intermittency. Also, the diurnal evolution of turbulence was accurately simulated, with probability density functions of resolved turbulent velocity fluctuations nearly identical to the lidar measurements. Explicit representation of turbulence in the stably‐stratified ABL was found to provide the right balance with larger scales, resulting in the development of intra‐hour variability as observed by the wind lidar; this variability was not captured by the mesoscale model. Moreover, multiscale simulations improved mean ABL characteristics such as horizontal velocity, vertical wind shear, and turbulence.
Addendum to Methyl bromide [BAT Value Documentation 2014]
Authors: Hallier E. , Müller M. , Drexler H. , Hartwig A. ,   MAK Commission
Published: April 2017

AbstractThe German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the BLW (“Biologischer Leitwert”) for methyl bromide, using bromide in serum/plasma to characterise the internal exposure. The critical effect of methyl bromide is a high acute and chronic neurotoxicity. It can pass through the skin so that biological monitoring is highly recommended.On the basis of results of a human study the occurrence of abnormal findings in the EEG is comparable for unexposed persons and persons with exposure to methyl bromide in concentrations below 12 mg bromide/l plasma. Thus the BLW of 12 mg bromide/l plasma or serum was confirmed. The sampling time for long‐term exposure is at the end of exposure/shift after several previous shifts.The evaluation of an EKA for methyl bromide in the air and S‐methylcysteine‐albumin adducts in blood is not possible as there is insufficient data available.
Di(2‐ethylhexyl) phthalate (DEHP) [MAK Value Documentation, 2016]
Authors: Hartwig A. ,   MAK Commission
Published: April 2017

AbstractThe German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the developmental toxicity of di(2‐ethylhexyl) phthalate (DEHP) [117‐81‐7]. In 2014, the maximum concentration at the work place (MAK value) of DEHP has been set to 2 mgm for the inhalable fraction.In some studies, a correlation between prenatal DEHP exposure and effects on anogenital distance of male newborns, birth weight and pregnancy duration in humans are found, however, the results are not consistent.Teratogenicity is observed in rats only at maternally toxic doses of 1000 mg/kg bw and day and above, in mice at 91 mg/kg bw and day. NOAELs for teratogenicity are 200 mg/kg bw and day for rats and 44 mg/kg body weight and day for mice, the latter corresponding to 29 mg/m3after scaling to a concentration at the work place. In contrast to mouse and marmoset the rat is very sensitive to DEHP effects on the male reproductive organs. From a three generation study the Commission deduces a NOAEL for pre‐ and postnatal developmental toxicity to the male reproductive organs and for fetotoxicity of 46 mg/kg bw and day for rats, corresponding to 54 mg/m3after scaling to a concentration at the work place. The reported effects, small testes, reduced absolute weights of testis and epididymis, are considered by the Commission as not being adverse because they do not show correlating consequences for the next generation or dose‐response relationship and changes in relative organ weights and histopathological correlates are not observed. After in utero exposure, germ cell organization, mRNA expression and protein level of StAR („steroidogenic acute regulatory protein“) in testes are affected at 100 mg/kg bw and day and above. These effects resulted in a NOAEL for prenatal developmental effects of the male reproductive organs of 30 mg/kg bw and day for rats, corresponding to 35 mg/m3. For mice in prenatal developmental studies a NOAEL for fetotoxicity as well as prenatal developmental toxicity of 48 mg/kg bw and day is derived, corresponding to 32 mg/m3. Damage to the embryo or foetus is unlikely when the MAK value is observed and DEHP is classified in Pregnancy Risk Group C.
N‐Ethyl‐2‐pyrrolidone (vapour) [MAK Value Documentation, 2016]
Authors: Hartwig A. ,   MAK Commission
Published: April 2017

Abstract

The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the work place (MAK value) of N‐ethyl‐2‐pyrrolidone [
2687‐91‐4
] of 2 ml/m
3
, considering the endpoints irritation of the respiratory tract and developmental toxicity.

The critical effect of N‐ethyl‐2‐pyrrolidone is degeneration of the olfactory epithelia in rats in a new 13‐week‐inhalation study. Since 2014, the Commission uses an empirical approach to set MAK values for substances with critical effects on the upper respiratory tract or the eyes. According to these proposals, the NOAEC of 62.6 mg/m
3
(13.3 ml/m
3
vapour) corresponds to a work place air concentration of 31 mg/m
3
(6.6 ml/m
3
). The irritating response in the 13 week study is not more pronounced than after shorter exposition times. Therefore the MAK‐value is increased to 5 ml/m
3
for the vapour phase only. Local effects are critical and only minimal irritation occurs at the LOAEC, therefore the assignment of N‐ethyl‐2‐pyrrolidone to Peak Limitation Category I and excursion factor 2 established in 2014 are retained. Also with the increased MAK value, damage to the embryo or foetus is unlikely when the MAK value is observed. Therefore, classification of N‐ethyl‐2‐pyrrolidone in Pregnancy Risk Group C is confirmed.
Iodine and inorganic iodides [MAK Value Documentation, 2014]
Authors: Hartwig A. ,   MAK Commission
Published: April 2017

AbstractThe German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has re‐evaluated the maximum concentration at the work place (MAK value) of iodine and inorganic iodides [7553‐56‐2], considering all endpoints.The critical effect of iodine and inorganic iodides are disturbances in thyroid function occurring after increased iodine or iodide intake. Because of the long history of iodine deficiency in Germany, there is a high prevalence of subclinical and manifest thyroid gland diseases. An increase in iodine intake is suspected of producing further disturbances in damaged thyroid glands. No MAK value has been established, and iodine remains listed in Section IIb of the List of MAK and BAT Values. This also applies for inorganic iodides. A relationship between the introduction of iodine supplementation and an increase in papillary thyroid tumours in humans cannot be confirmed. Iodine and inorganic iodides are not classified in the categories for Carcinogens or Germ Cell Mutagens. Skin contact may contribute significantly to systemic toxicity and iodine and inorganic iodides are designated with an “H” notation. Sensitization is not expected from the limited data.
Increased respiratory volume at the workplace – Significance for the derivation of the MAK value [MAK Value Documentation, 2017]
Authors: Hartwig A. ,   MAK Commission
Published: April 2017

Abstract
The German Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area has evaluated whether MAK values which are derived from systemic effects in inhalation experiments in animals or in volunteers at rest should reflect that the respiratory volume at the workplace, and therefore the amount taken up, is higher than under these experimental conditions.

Assuming that the same external concentration in the air leads to the same internal exposure in all species at rest, it is taken into account when extrapolating data from inhalation studies in animals to humans that in the case of systemic effects the body burden (related to kg body weight) of the worker at the workplace, with an assumed respiratory volume of 10 m
3
in 8 hours, is about twice as high as that of the experimental animal in the usual 6‐hour experiment. The equivalent external concentration at the workplace is, therefore, half of that used in the experiment. This extrapolation applies only for gases and vapours with a blood:air distribution coefficient of > 5 and for aerosols, provided that the effect is the product of cd7;t. If it can be shown that the critical effect depends more on the concentration than the product of cd7;t and that the steady state was reached within the duration of the experiment, the equivalent concentration at the workplace is two thirds of the concentration used in the experiment, as then extrapolation of the usual 6‐hour exposure in animal experiments to the 8‐hour exposure at the workplace is no longer necessary.

When deriving MAK values for systemic effects from studies with volunteers at rest, the MAK value is established at half of the concentration used in the volunteer study, which is calculated from the ratio of the respiratory volume of workers to that of persons at rest. Gases and vapours with a blood:air distribution coefficient of < 5 represent an exception. In addition, the results are extrapolated to the longer daily exposure at the workplace, unless there are toxicokinetic data available that show this to be unnecessary. If there are valid PBPK models of exposure with the relevant metabolites in humans and animals, these are used for extrapolation from the experimental animal to persons at the workplace.
Feasibility trial for primary stroke prevention in children with sickle cell anemia in Nigeria (SPIN trial)
Authors: Galadanci Najibah A. , Umar Abdullahi Shehu , Vance Leah D. , Musa Tabari Abdulkadir , Ali Shehi , Belonwu Raymond , Salihu Auwal , Amal Galadanci Aisha , Wudil Jibir Binta , Bello‐Manga Halima , Neville Kathleen , Kirkham Fenella J. , Shyr Yu , Phillips Sharon , Covert Brittany V. , Kassim Adetola A. , Jordan Lori C. , Aliyu Muktar H. , DeBaun Michael R. 
Published: April 2017

AbstractThe vast majority of children with sickle cell anemia (SCA) live in Africa, where evidence‐based guidelines for primary stroke prevention are lacking. In Kano, Nigeria, we conducted a feasibility trial to determine the acceptability of hydroxyurea therapy for primary stroke prevention in children with abnormal transcranial Doppler (TCD) measurements. Children with SCA and abnormal non‐imaging TCD measurements (≥200 cm/s) received moderate fixed‐dose hydroxyurea therapy (∼20 mg/kg/day). A comparison group of children with TCD measurements <200 cm/s was followed prospectively. Approximately 88% (330 of 375) of families agreed to be screened, while 87% (29 of 33) of those with abnormal TCD measurements, enrolled in the trial. No participant elected to withdraw from the trial. The average mean corpuscular volume increased from 85.7 fl at baseline to 95.5 fl at 24 months (not all of the children who crossed over had a 24 month visit), demonstrating adherence to hydroxyurea. The comparison group consisted of initially 210 children, of which four developed abnormal TCD measurements, and were started on hydroxyurea. None of the monthly research visits were missed (n = total 603 visits). Two and 10 deaths occurred in the treatment and comparison groups, with mortality rates of 2.69 and 1.81 per 100 patient‐years, respectively (P = .67). Our results provide strong evidence, for high family recruitment, retention, and adherence rates, to undertake the first randomized controlled trial with hydroxyurea therapy for primary stroke prevention in children with SCA living in Africa.
ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT
Authors: Canaani Jonathan , Savani Bipin N. , Labopin Myriam , Michallet Mauricette , Craddock Charles , Socié Gerard , Volin Lisa , Maertens Johan A. , Crawley Charles , Blaise Didier , Ljungman Per T. , Cornelissen Jan , Russell Nigel , Baron Frédéric , Gorin Norbert , Esteve Jordi , Ciceri Fabio , Schmid Christoph , Giebel Sebastian , Mohty Mohamad , Nagler Arnon 
Published: April 2017

AbstractABO incompatibility is commonly observed in stem cell transplantation and its impact in this setting has been extensively investigated. HLA‐mismatched unrelated donors (MMURD) are often used as an alternative stem cell source but are associated with increased transplant related complications. Whether ABO incompatibility affects outcome in MMURD transplantation for acute myeloid leukemia (AML) patients is unknown. We evaluated 1,013 AML patients who underwent MMURD transplantation between 2005 and 2014. Engraftment rates were comparable between ABO matched and mismatched patients, as were relapse incidence [34%; 95% confidence interval (CI), 28–39; for ABO matched vs. 36%; 95% CI, 32–40; for ABO mismatched; P = .32], and nonrelapse mortality (28%; 95% CI, 23–33; for ABO matched vs. 25%; 95% CI, 21–29; for ABO mismatched; P = .2). Three year survival was 40% for ABO matched and 43% for ABO mismatched patients (P = .35), Leukemia free survival rates were also comparable between groups (37%; 95% CI, 32–43; for ABO matched vs. 38%; 95% CI, 33–42; for ABO mismatched; P = .87). Incidence of grade II‐IV acute graft versus host disease was marginally lower in patients with major ABO mismatching (Hazard ratio of 0.7, 95% CI, 0.5–1; P = .049]. ABO incompatibility probably has no significant clinical implications in MMURD transplantation.
Chemical and Biological Aspects of Nutritional Immunity—Perspectives for New Anti‐Infectives that Target Iron Uptake Systems
Authors: Bilitewski Ursula , Blodgett Joshua A. V. , Duhme‐Klair Anne‐Kathrin , Dallavalle Sabrina , Laschat Sabine , Routledge Anne , Schobert Rainer 
Published: April 2017

AbstractUpon bacterial infection, one of the defense mechanisms of the host is the withdrawal of essential metal ions, in particular iron, which leads to “nutritional immunity”. However, bacteria have evolved strategies to overcome iron starvation, for example, by stealing iron from the host or other bacteria through specific iron chelators with high binding affinity. Fortunately, these complex interactions between the host and pathogen that lead to metal homeostasis provide several opportunities for interception and, thus, allow the development of novel antibacterial compounds. This Review focuses on iron, discusses recent highlights, and gives some future perspectives which are relevant in the fight against antibiotic resistance.
Single‐Domain Ferromagnet of Noncentrosymmetric Uniaxial Magnetic Ions and Magnetoelectric Interaction
Authors: Koo Hyun‐Joo , Gordon Elijah E. , Whangbo Myung‐Hwan 
Published: April 2017

AbstractThe feasibility of a single‐domain ferromagnet based on uniaxial magnetic ions was examined. For a noncentrosymmetric uniaxial magnetic ion of magnetic moment μ at a site of local electric dipole moment p, it is unknown to date whether μ prefers to be parallel or antiparallel to μ. The nature of this magnetoelectric interaction was probed in terms of analogical reasoning based on the Rashba effect and density functional theory (DFT) calculations. We show that μ and p prefer an antiparallel arrangement, predict that Fe‐doped CaZnOS is a single‐domain ferromagnet like a bar magnet, and find the probable cause for the ferromagnetism and weak magnetization hysteresis in Fe‐doped hexagonal ZnO and ZnS at very low dopant concentrations.