bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of red blood profiles and oxygen transport capacity of elite and sub-elite wrestlers
Authors: Ozal Mehmet , Cengiz Asim , Yaman Metin , Guclu Mehmet 
Published: August 2016

This study aimed to compare the red blood profiles’ that are determinants of oxygen transports system, of elite wrestlers with sub-elite wrestlers. This study consists of a twenty-one elite wrestlers representing national team of Turkey who volunteered to participate in the study. Biochemical parameters were determined during transition period and the bloods were drawn in a resting state for each participant. A paired T tests was used to check the variations in hematological parameters. There are no significant differences between the groups except age. Elite wrestlers age was found to be significantly higher than sub elite wrestlers (p = 0.019 <0.005). RBC, HGB, HCT, MCH, MCHC were within normal limits and also for athletes indicates a positive development and there were no significant differences between the groups. Training increases total hemoglobin mass by stimulating erythropoiesis, which increases the amount of O2 that can be carried by blood. regular screening of hematological variables is desirable as many athletes have values near or below the lower limit of the normal range.
An optimization study for radioiodination of a new synthesized benzamide derivative as an analogue tracer for malignant melanoma imaging
Authors: Kandil Shaban A. , Aglan Hany , EL-Kafrawy Ahmed F. , Seddik Usama 
Published: August 2016

Abstract
Iodobenzamides are reported to possess some affinity for melanoma. This study describes the synthesis of a new benzamide analogue, N-(2-diethylamino-ethyl)-4-(4-chloro-nicotinamido)-5-[125I]iodo-2-methoxybenzamide ([125I]H4) designed to target melanoma. The synthesis was simply achieved in four steps. There were two PyCIU/DIPEA amide condensations and a transfer hydrogenation using an ammonium formate hydrogen donor. The radioiodination step was carried out with 125I via an electrophilic substitution reaction. The reaction conditions were optimized. The labeled compound was purified by HPLC. The maximum radiochemical yield was found to be 78% at a radiochemical purity of 98%. All compounds were characterized by MS and NMR techniques. The log P value for [125I]H4 was found as 3.96±0.5.
Scenario aggregation method for portfolio expectile optimization
Authors: Jakobsons Edgars 
Published: August 2016

Abstract
The statistical functional expectile has recently attracted the attention of researchers in the area of risk management, because it is the only risk measure that is both coherent and elicitable. In this article, we consider the portfolio optimization problem with an expectile objective. Portfolio optimization problems corresponding to other risk measures are often solved by formulating a linear program (LP) that is based on a sample of asset returns. We derive three different LP formulations for the portfolio expectile optimization problem, which can be considered as counterparts to the LP formulations for the Conditional Value-at-Risk (CVaR) objective in the works of Rockafellar
and Uryasev [43], Ogryczak and Śliwiński [41] and Espinoza and Moreno [21]. When the LPs are based on a simulated sample of the true (assumed continuous) asset returns distribution, the portfolios obtained from the LPs are only approximately optimal. We conduct a numerical case study estimating the suboptimality of
the approximate portfolios depending on the sample size, number of assets, and tail-heaviness of the asset returns distribution. Further, the computation times using the three LP formulations are analyzed, showing that the formulation that is based on a scenario aggregation approach is considerably faster than the two alternatives.
Ordering Antinomy: An Analysis of Early Mormonism's Priestly Offices, Councils, and Kinship
Authors: Flake Kathleen 
Published: August 2016

AbstractMormonism's founder Joseph Smith created a complex and hieratic priestly structure within a radically democratizing nation. His stated goal was to convey to all the faithful what he believed to be his own powers of prophecy and priestly mediation of divine presence. Thus, out of historiographic arguments about where to place Mormonism within the narrative of antebellum religious polity there arises a potentially more essential question: how did early Mormonism sustain any structural coherence, much less the order it was famous for? This essay argues that Smith avoided the atomization of his movement by creating three power structures and assigning every believer a status in each. Thus, status was not absolute or static: it shifted as the person moved among the three sites of power. Or, in other words, the degree and nature of the authority held by anyone at any give time was particular to the locus of the power – office, council, or kinship – not the person. These shifting status relationships stabilized Mormonism's potentially self-destructive antinomianism and, as a historiographical matter, have been mistaken for populism. The power struggles this occasioned within his movement, particularly over Smith's inclusion of women in his priestly hierarchy, weakened his vision of reciprocal authority and shifting jurisdiction. Compromised by romanticized gender norms, but not abandoned, this power structure continues to constitute the governing structure of Mormonism, leaving it still republican in style, not substance. Historiographically, it is hoped that this closer analysis of Mormonism's polity illuminates the existence of alternatives to regnant tropes on the nature of antebellum religion and contributes to better understanding of the means by which at least one perfectionist religion has survived notwithstanding its radically antinomian tendencies.
La disidencia ante la justicia. Reacciones frente a la crisis de la monarquía en el Río de la Plata, 1808-1810
Authors: Polastrelli Irina 
Published: August 2016

<strong></strong><p><strong></strong>A partir del expediente judicial abierto entre 1808 y 1810 contra Saturnino Rodríguez Peña y Diego Paroissien por sus proyectos “independentistas” para el Río de la Plata, se muestran las diversas reacciones, los “miedos” y las “esperanzas” que generó la crisis de la monarquía. El artículo expone algunos de los rasgos de la disidencia política mediante la definición del delito denunciado, así como las estrategias y los argumentos utilizados por los actores intervinientes en la causa para asegurar sus posiciones en el desconcierto provocado por la vacancia real.</p><p align="center"><strong> </strong></p>
Los trabajadores del Ferrocarril de Tehuantepec y la huelga “olvidada” de Rincón Antonio (1903)
Authors: Sedano Ortega Mauricio 
Published: August 2016

<p align="center"> </p><p align="center">En este artículo pretendemos, a partir de fuentes principales como son los telegramas enviados durante el conflicto, demostrar que la huelga de trabajadores de Rincón Antonio –pequeña población oaxaqueña del Istmo– fue uno de las primeras acciones de inconformidad contra las políticas laborales de principio del siglo xx en México. Para lograr nuestro objetivo, analizaremos los espacios donde se desarrolló la huelga, los lugares donde laboraban los empleados y los sueldos que recibían, además de la participación de la Unión de Mecánicos Mexicanos.</p><p align="center"> </p><p align="center"><strong> </strong></p>
De las urnas a la movilización popular. Elecciones presidenciales de 1970 en Colombia
Authors: Acuña Rodríguez Olga Yanet 
Published: August 2016

<p>El texto resalta cómo el inconformismo de los sectores populares con el tradicionalismo político, liberal-conservador en Colombia y con las irregularidades en el conteo y reconteo de los votos en las elecciones presidenciales de 1970, pusieron en crisis al régimen político “frentenacionalista”, y a su candidato Misael Pastrana Borrero. Desde la historia política y social se analiza el papel de las masas y las posiciones y acciones de las elites para legitimar el poder; así, el evidente fraude electoral en las elecciones del 19 de abril de 1970 fue asumido por las masas como una burla al sistema democrático y a su expresión como ciudadanos, lo que motivó movilizaciones en diversas regiones del país. A partir de este hecho los actores sociales reivindicaron su papel como ciudadanos y reclamaron sus derechos, acudiendo a la denuncia en las diversas instituciones, a la movilización y a la protesta y, tres años después, a la movilización armada que se denominó M-19.</p><p> </p><p> </p><br /><table border="0" cellspacing="0" cellpadding="0"><tbody><tr><td valign="top" width="299"> </td><td valign="top" width="299"> </td></tr></tbody></table>
Similarities and Differences of International Practices and Procedures for the Regulation for Active Substance Master Files/Drug Master Files of Human Use: Moving Toward Regulatory Convergence
Authors: Matsuhama Maki , Takishita Tomoko , Kuribayashi Ryosuke , Takagi Kazunori , Wakao Rika , Mikami Kenichi 
Published: August 2016

Purpose. A gap analysis survey of international practices for Active Substance Master Files (ASMFs)/Drug Master Files (DMFs) of human use was conducted as a project of the ASMF/DMF working group of the International Generic Drug Regulators Pilot (IGDRP) to identify similarities and differences among ASMF/DMF procedures of 10 IGDRP members and 2 observers. Methods. We conducted a questionnaire survey and compared the following aspects: overall ASMF/DMF procedures, submission requirements for ASMFs/DMFs, assessment processes for ASMFs/DMFs, the technical requirements for active pharmaceutical ingredients (APIs), generation of assessment reports for ASMFs/DMFs, procedures for changing ASMF/DMF details, and Good Manufacturing Practice (GMP) inspection/certification of API manufacturers. Twelve organizations participated in this project: the Brazilian Health Surveillance Agency (Anvisa), the European Union (EU), Health Canada (HC), the Singapore Health Sciences Authority (HSA), the South African Medicines Control Council (MCC), the South Korean Ministry of Food and Drug Safety (MFDS), the Japanese Pharmaceuticals and Medical Devices Agency (PMDA), the Swiss Agency for Therapeutic Products (Swissmedic), the Taiwan Food and Drug Administration (TFDA), the Australian Therapeutic Goods Administration (TGA), the European Directorate for the Quality of Medicines & HealthCare (EDQM) (Observer) and the Prequalification Team (PQT) of the World Health Organization (WHO), which includes the PQT–Medicines (Observer). Results. Although there were many similarities among the participating agencies surveyed, there were also differences that should be discussed such as assessment processes of ASMFs/DMFs and Technical requirements for APIs. Conclusions. These differences revealed by this survey will be key considerations in order to facilitate the filing of ASMFs/DMFs globally and to establish a framework for sharing and utilizing information related to ASMFs/DMFs among IGDRP members in the future. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Onset of Action and Efficacy of Ibuprofen Liquigel as Compared to Solid Tablets: A Systematic Review and Meta-Analysis
Authors: Lawati Hanan Al , Jamali Fakhreddin 
Published: August 2016

Purpose. Ibuprofen liquigel has been believed to provide faster analgesic effect. However, comparative studies evaluating the efficacy of liquigel versus regular tablets are not available. Hence, we carried out a systematic review and a meta-analysis to compare the onset of action and efficacy of over-the-counter doses of ibuprofen liquigel (IBULG) vs ibuprofen tablets (IBUT). Methods. Published clinical trials of IBULG and IBUT were identified through a systematic search of various data bases up to October, 2015. Results. In total 18 eligible studies on IBUT and 4 on IBULG were found. There was no significant difference in the median time to the first perceptible pain relief or the proportion of patients with more than 50% pain relief between the two products. However, IBULG yielded significantly greater odd ratios in meaningful pain relief at 60, 90 and 120 min, but not at 30 min, as compared with IBUT. Conclusion. The available evidence, although not overwhelming, suggest a faster onset of analgesia for liquigel as compared with tablets. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Crystal-liquid Fugacity Ratio as a Surrogate Parameter for Intestinal Permeability
Authors: Zakeri-Milani Parvin , Fasihi Zohreh , Akbari Jafar , Jannatabadi Ensieh , Barzegar-Jalali Mohammad , Loebenberg Raimar , Valizadeh Hadi 
Published: August 2016

Background: We assessed the feasibility of using crystal-liquid fugacity ratio (CLFR) as an alternative parameter for intestinal permeability in the biopharmaceutical classification (BCS) of passively absorbed drugs. Methods: Dose number, fraction of dose absorbed, intestinal permeability, and intrinsic dissolution rate were used as the input parameters. CLFR was determined using thermodynamic parameters i.e., melting point, molar fusion enthalpy, and entropy of drug molecules obtained using differential scanning calorimetry. Results: The CLFR values were in the range of 0.06-41.76 mole percent. There was a close relationship between CLFR and in vivo intestinal permeability (r > 0.8). CLFR values of greater than 2 mole percent corresponded to complete intestinal absorption. Applying CLFR versus dose number or intrinsic dissolution rate, more than 92% of tested drugs were correctly classified with respect to the reported classification system on the basis of human intestinal permeability and solubility. Conclusion: This investigation revealed that the CLFR might be an appropriate parameter for quantitative biopharmaceutical classification. This could be attributed to the fact that CLFR could be a measure of solubility of compounds in lipid bilayer which was found in this study to be directly proportional to the intestinal permeability of compounds. This classification enables researchers to define characteristics for intestinal absorption of all four BCS drug classes using suitable cutoff points for both intrinsic dissolution rate and crystal-liquid fugacity ratio. Therefore, it may be used as a surrogate for permeability studies. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
PLACE AND IDENTITY: Reading From God’s Spider at the Federation Of Humanities And Social Sciences Congress
Authors: Dabydeen Cyril 
Published: August 2016

Being a guest-writer at the Federation of Humanities and Social Sciences Congress was an honour. I thank the Canadian Association of Commonwealth Language and Literature Studies (CACLALS) and the Association for Canadian and Quebec Literatures (ACQL) for hosting me to read from my new volume, God’s Spider (Peepal Tree Press, UK)–a shortlisted finalist for the Guyana Prize for Literature (Best Poetry Book category). Indeed, a reading is always a special occasion for me; it’s also a time of liminality–in-betweenness, if you will-- placelessness, a void, quest, looking or yearning for an identity; and being nowhere, but searching. Wanting. As a preamble to my reading, I touched on W.H. Auden’s view that a poet should “mythologize the ground on which he walks.” Having now lived for over four decades in Canada, I am well equipped to do this: mythologizing Canada, sometimes with post-colonial verve and style, or angst. Post-colonial, presumably because all art is political (see Salman Rushdie’s essays in his Outside the Whale).
Sampling for Soil Carbon Stock Assessment in Rocky Agricultural Soils
Authors: Beem-Miller Jeffrey P. , Kong Angela Y.Y. , Ogle Stephen , Wolfe David 
Published: August 2016

Core Ideas
Soil mass is the greatest source of uncertainty for C stocks on rocky soils.
Coring methods underestimate soil rock fragment content.
Hammer coring methods underestimate soil mass.
Mass‐based C stock reporting can overcome coring method bias.
Rotary corers are a cost‐competitive and less biased alternative to standard corers.
Coring methods commonly employed in soil organic C (SOC) stock assessment may not accurately capture soil rock fragment (RF) content or soil bulk density (ρb) in rocky agricultural soils, potentially biasing SOC stock estimates. Quantitative pits are considered less biased than coring methods but are invasive and often cost‐prohibitive. We compared fixed‐depth and mass‐based estimates of SOC stocks (0.3‐m depth) for hammer, hydraulic push, and rotary coring methods relative to quantitative pits at four agricultural sites ranging in RF content from <0.01 to 0.24 m3 m−3. Sampling costs were also compared. Coring methods significantly underestimated RF content at all rocky sites, but significant differences (p < 0.05) in SOC stocks between pits and corers were only found with the hammer method using the fixed‐depth approach at the <0.01 m3 m−3 RF site (pit, 5.80 kg C m−2; hammer, 4.74 g C m−2) and at the 0.14 m3 m−3 RF site (pit, 8.81 kg C m−2; hammer, 6.71 kg C m−2). The hammer corer also underestimated ρb at all sites as did the hydraulic push corer at the 0.21 m3 m−3 RF site. No significant differences in mass‐based SOC stock estimates were observed between pits and corers. Our results indicate that (i) calculating SOC stocks on a mass basis can overcome biases in RF and ρb estimates introduced by sampling equipment and (ii) a quantitative pit is the optimal sampling method for establishing reference soil masses, followed by rotary and then hydraulic push corers.
Effect of Cogranulation on Oxidation of Elemental Sulfur: Theoretical Model and Experimental Validation
Authors: Degryse Fien , da Silva Rodrigo C. , Baird Roslyn , McLaughlin Mike J. 
Published: August 2016

Core Ideas
Fertilizers with ES are usually in granular form.
Cogranulation of ES reduces its oxidation rate.
This granulation effect was modeled based on the reduction in effective surface area.
The model was verified against experimental data for ES‐fortified fertilizers.
Most studies on elemental sulfur (ES) oxidation have focused on small ES particles mixed through soil, even though commercial ES fertilizers are usually in granular form. Although it has been recognized that cogranulation of ES decreases its oxidation rate, no attempt has been made to quantify this effect. We developed a conceptual model that predicts the “effective diameter” (the diameter of ES particles mixed through soil that would oxidize at the same rate as the granulated ES) by taking into account the effect of granulation on the effective surface area available to the ES in the granule cavity after the soluble macronutrient compound in the fertilizer has diffused away. To validate the model, the oxidation rate was determined for ES‐fortified monoammonium phosphate fertilizer with varying ES content (20–250 g kg−1), ES particle diameter (25 or 60 μm), and granule diameter (1.8 or 3.4 mm). The time to reach 50% oxidation varied from 17 d for small granules at the lowest ES content to 210 d for the large granules with the highest ES content. In agreement with the model predictions, reducing ES particle size did not affect the oxidation rate except at the lowest ES rate, whereas reducing granule size increased the oxidation rate. Predicted and observed oxidation rates were in good agreement, indicating that the model describes the effect of granulation with reasonable accuracy. This model may assist in improving formulation of ES‐containing fertilizers and guiding fertilizer recommendations.
Regeneración de Sedum praealtum A.DC (siempreviva) vía organogénesis
Authors: Ruvalcaba Ruiz Domingo 
Published: August 2016

La siempreviva (Sedum praealtum A.DC) pertenece a la familia Crassulaceae, desde hace mucho tiempo ha sido utilizada en la etnobotánica mexicana como un agente anti-inflamatorio y analgésico, en el tratamiento de dolor de dientes, amigdalitis, para enfermedades de los ojos, erupciones cutáneas y de regeneración de tejidos, recientemente se le descubrieron compuestos con actividad antioxidante que presentan efectos hepatoprotector y anticancerígeno.Se estableció un protocolo eficiente de regeneración mediante organogénesis para Sedum praealtum a partir de hojas jóvenes de plantas provenientes de vivero. Fragmentos de hoja que contenían la parte media se cultivaron en medio Murashige y Skoog adicionado con bencilaminopurina (6-BAP) y 2,4-Diclorofenoxiacético (2,4-D) en varias combinaciones. A los 90 días de haber iniciado el cultivo, el tratamiento suplementado con 0.5 mg/L de 6-BAP, 0.0 mg/L de 2,4-D mostró efectos significativos sobre el desarrollo de órganos por la vía indirecta, dando en promedio 13.0±0.3 brotes por explante. Los brotes se individualizaron y se transfirieron a medio MS suplementado con 2.0 mg/L de ácido indolacético (AIA) para su enraizamiento.
Development of urban transport system of U.D. Samara
Authors: Pavlova Larisa Nikolaevna 
Published: August 2016

In the article some problems related to development processes of urban transport system in general and in U.D. Samara are discussed. Problems arising during development process of urban transport system are presented. Main principles of development of Samara urban transport system are expounded. Development concepts of the road network of the urban district Samara are formulated.