bluuebunny/crossref_metadata_2025_split huggingface dataset:
AVALIAÇÃO DE PLANTIOS DE PARICÁ (<i>Schizolobum parahyba </i>var. <i>amazonicum</i> (Huber ex Ducke) Barneby DE DIFERENTES IDADES E SISTEMAS DE CULTIVO NO MUNICÍPIO DE AURORA DO PARÁ - PA (BRASIL)
Authors: Cordeiro Iracema Maria Castro Coimbra , Barros Paulo Luiz Contente de , Lameira Osmar Alves , Gazel Filho Aderaldo Batista 
Published: March 2016

http://dx.doi.org/10.5902/1980509819618O trabalho teve o objetivo de avaliar o comportamento da espécie Schizolobum parahyba var. amazonicum (Huber ex Ducke) Barneby (paricá) de diferentes idades e sistemas de cultivo no município de Aurora do Pará (PA - Brasil). O experimento foi conduzido no campo experimental Tramontina Belém S.A (2°10’00”S; 47°32’00”W), seguindo o delineamento estatístico inteiramente ao acaso com parcelas subdivididas. Foram selecionadas seis plantações florestais de paricá: 1 - Sistema agroflorestal de paricá + curauá (Ananas comosus var. erectifolius) (SAFpc); 2 - monocultivo de paricá (MONp); 3 - Sistema agroflorestal paricá, freijó (Cordia goeldiana Huber) e curauá (SAFpfc); 4 - Consórcio paricá e freijó (CONpf); 5 - Sistema agroflorestal paricá, mogno (Switenia macrophylla King), freijó e curauá (SAFpmfc); e 6 - Consórcio paricá, mogno e+ freijó (CONpmf). O tamanho da parcela foi de 18 x 24 m com quatro repetições por tratamento, perfazendo um total de 28 parcelas e 10.368 m2 de área experimental. As variáveis obtidas para inferir sobre crescimento do paricá foram altura (H) e diâmetro a altura do peito (DAP) e, a partir delas, foram calculados Incrementos Médios Anuais em DAP (IMAdap) e H (IMAalt) e o volume (V). Os dados foram submetidos à análise de variância e as médias comparadas através do teste SNK a 95% de probabilidade. Os resultados indicaram que o paricá quando associado ao curauá apresentou resultados estatisticamente superiores de incremento em altura e diâmetro a altura do peito e volume, quando comparados com os tratamentos da mesma idade na ausência da espécie agrícola.
EFEITO DOS ÁCIDOS INDOLBUTÍRICO E NAFTALENOACÉTICO NO ENRAIZAMENTO DE ESTACAS SEMILENHOSAS DE <i>Cordia trichotoma</i> (Vell.) Arrab. ex Steud.
Authors: Faganello Luiz Roberto , Dranski João Alexandre Lopes , Malavasi Ubirajara Contro , Malavasi Marlene de Matos 
Published: March 2016

http://dx.doi.org/10.5902/1980509820584O presente trabalho objetivou avaliar os efeitos de diferentes concentrações de ácido indolbutírico e do ácido α-naftaleno acético no enraizamento de estacas semilenhosas coletadas de brotações de mudas de Cordia trichotoma. As mudas foram produzidas por sementes, constituindo um jardim miniclonal com posterior poda da parte aérea. As brotações foram colhidas resultando em estacas semilenhosas com 12,0 cm de comprimento e, 5,5 mm de diâmetro e um par de folhas na porção apical reduzida pela metade. Os tratamentos compreenderam a imersão rápida da base das estacas em ácido indolbutírico (AIB) e ácido α-naftaleno acético (ANA) nas concentrações de 0, 2.000, 4.000, 6.000, 8.000 mg L-1 em delineamento de blocos casualizados com arranjo bifatorial 2 x 5. Após 60 dias do estaqueamento, foram avaliados a porcentagem de enraizamento, o número e comprimento das raízes, a porcentagem de brotações, o número de brotos e folhas novas, a porcentagem de estacas com calos, assim como a sobrevivência e mortalidade. O fitorregulador AIB na concentração de 8.000 mg L-1 promoveu maior enraizamento, resultando em 28,9% das estacas enraizadas, e com maior número de raízes por estaca. Para o ANA, não houve efeito significativo sobre o enraizamento. O aumento crescente da concentração dos fitorreguladores reduziu linearmente a emissão de brotações e folhas novas e aumentou linearmente a mortalidade de estacas, afetando negativamente os componentes da parte aérea das estacas semilenhosas de Cordia trichotoma.
Resolution of Concussion Symptoms After Osteopathic Manipulative Treatment: A Case Report
Authors: Guernsey David T. , Leder Adena , Yao Sheldon 
Published: March 2016

Abstract
A concussion is the result of a biomechanical force directed toward the head, causing neurologic dysfunction. The inflammatory response and the production of reactive oxygen species are proposed mechanisms for the symptoms and long-term sequelae of concussion. Osteopathic manipulative treatment (OMT) may help reduce inflammation by improving glymphatic flow. The authors describe the effect of OMT on a patient with mild concussion symptoms, including nausea, dizziness, tinnitus, and imbalance. The patient was evaluated with the Sensory Organization Test before and after undergoing a 25-minute session of OMT. After the session, the patient reported resolution of symptoms, and his sensory organization test score improved by 6 points. The role of OMT must be further investigated as an essential and cost-effective tool in the management of concussions.
An examination of clinical differences between carriers and non-carriers of chromosome 8q24 risk alleles in a New Zealand Caucasian population with prostate cancer
Authors: Bishop Karen S. , Han Dug Yeo , Karunasinghe Nishi , Goudie Megan , Masters Jonathan G. , Ferguson Lynnette R. 
Published: March 2016

Background.Prostate cancer makes up approximately 15% of all cancers diagnosed in men in developed nations and approximately 4% of cases in developing nations. Although it is clear that prostate cancer has a genetic component and single nucleotide polymorphisms (SNPs) can contribute to prostate cancer risk, detecting associations is difficult in multi-factorial diseases, as environmental and lifestyle factors also play a role. In this study, specific clinical characteristics, environmental factors and genetic risk factors were assessed for interaction with prostate cancer.Methods.A total of 489 prostate cancer cases and 427 healthy controls were genotyped for SNPs found on chromosome 8q24 and a genetic risk score was calculated. In addition the SNPs were tested for an association with a number of clinical and environmental factors.Results.Age and tobacco use were positively associated, whilst alcohol consumption was negatively associated with prostate cancer risk. The following SNPs found on chromosome 8q24 were statistically significantly associated with prostate cancer:rs10086908,rs16901979;rs1447295andrs4242382. No association between Gleason score and smoking status, or between Gleason score and genotype were detected.Conclusion.A genetic risk score was calculated based on the 15 SNPs tested and found to be significantly associated with prostate cancer risk. Smoking significantly contributed to the risk of developing prostate cancer, and this risk was further increased by the presence of four SNPs in the 8q24 chromosomal region.
High School General Point Average (GPA) as Basis for Students' Academic Performance in College
Authors: Ensoy Celso P. , Lavega Melinda L. 
Published: March 2016

One of the determinants for a successful career is academic performance. The study sought to determine the academic performance of freshmen Education students from the school years 2010-2013. The data were gathered through prepared questionnaires. Collected data were analyzed through frequency counts, percentage, and measure of central tendency. Results showed that more female students were attracted to teaching profession. Moreover, it was discovered that their parents are farmers and housekeepers with an average monthly income of Php 9, 752.92 (216 USD) only. Most of the respondents graduated from public high schools. Some of them did not meet CHED's grade requirement of 85% when enrolled. Test of relationship between high school and college GPAs (academic performance) showed a moderate inverse relationship. The Analysis of Variance (ANOVA) showed a significant linear relationship between high school (GPA) and college (GPA) at .01 alpha level of significance. Therefore, students' academic performance in college can be determined by their high school GPA. With this, CHED's regulating policy during enrollment should be strictly practiced in the Visayas State University (VSU), Philippines. Lastly, the College of Education should impose retention scheme for freshmen Education students especially for males.
Psychotropic medication use in hospitalized patients with borderline personality disorder
Authors: Moeller Karen E , Din Amad , Wolfe Macey , Holmes Grant 
Published: March 2016

Abstract

Introduction: Use of medications to treat symptoms of borderline personality disorder (BPD) is controversial. The purpose of this study was to describe psychotropic medication use in hospitalized patients with BPD and compare with a control group.

Methods: A retrospective chart review was conducted on hospitalized patients aged 18-65 years having a diagnosis of BPD and compared them with a control group of patients with a diagnosis of major depressive disorder (MDD) without a personality disorder. Patients were excluded from the BPD group if other personality disorders were recorded. Charts were reviewed for demographics and psychotropic medication usage both prior to admission and at discharge.

Results: This study included 165 patients (85 in BPD; 80 in MDD). Prior to admission and upon discharge, patients in the BPD group were prescribed significantly more psychotropic medications than patients with MDD (3.21 vs 2.10; P < .001 and 2.87 vs 2.35; P < .05, respectively). Patients in the BPD group were significantly more likely to be prescribed antipsychotics, mood stabilizers, and miscellaneous agents compared with the MDD group. On admission, significantly more BPD patients were prescribed multiple sedative agents (37.6% vs 21.3%; P < .05), but because of the discontinuation of sedative agents, this difference was nonsignificant upon discharge.

Discussion: This study found increased medication utilization among patients with BPD. Polypharmacy may increase the risk of side effects, drug interactions, and drug toxicity for BPD patients. Clinicians need to carefully evaluate the efficacy and risk of medications prescribed in patients with BPD.
New perspective on the transition from flat to steeper subduction in Oaxaca, Mexico, based on seismicity, nonvolcanic tremor, and slow slip
Authors: Fasola Shannon , Brudzinski Michael R. , Ghouse Noorulann , Solada Katharine , Sit Stefany , Cabral‐Cano Enrique , Arciniega‐Ceballos Alejandra , Kelly Nicholas , Jensen Kevin 
Published: March 2016

AbstractWe examine the along‐strike transition from flat to steeper subduction in Oaxaca, Mexico, to provide a better understanding of what controls the slab morphology. Prior studies have suggested the slab tends to tear along the transitions in dip as the slab rolls back. We determine the slab geometry based on local seismicity, nonvolcanic tremor (NVT), and slow slip utilizing a deployment of broadband seismometers and continuous GPS receivers distributed in and around Oaxaca. We construct depth contours of the subducting slab surface down to 100 km, which illustrate that the transition from flat to steeper subduction occurs rapidly via a sharper flexure than previously recognized. The prior catalog of NVT in Oaxaca is extended using the same method and additional stations that extend further west. The band of NVT follows the new slab contours, widening toward the west with the downdip extent gradually moving inland. The amount of NVT also correlates with the strength of an ultraslow‐velocity layer. There are no gaps in seismicity, NVT, or slow slip across the rapid transition in slab dip, further supporting the notion that the slab is not currently torn in the updip region. We propose that the sharp flexure is possible in this region due to bending moment saturation that leads to greater curvature in both the downdip and along‐strike directions. A similar set of observations in southern Peru suggests this is a viable alternative to tearing that accommodates the large strains from variable rates of slab rollback.
Influence of soil frost on the character and degradability of dissolved organic carbon in boreal forest soils
Authors: Panneer Selvam B. , Laudon H. , Guillemette F. , Berggren M. 
Published: March 2016

AbstractRecent studies suggest that increases in extent and duration of winter soil frost increases dissolved organic carbon (DOC) concentrations in boreal riparian soils and connected aquatic systems during the subsequent spring and summer. However, little is known about the impact of frost on DOC character and its degradability. We applied three experimental treatments to riparian soils in northern Sweden—shallow soil frost (insulated), deep soil frost (snow removed) and control plots—to test the effect of different soil frost regimes on the chemical characteristics and degradability of soil DOC. Soil pore water samples were analyzed using excitation‐emission fluorescence (parallel factor analysis) combined with biological and photochemical degradation experiments. We found that the absolute bacterial metabolic rates were significantly lower in samples from the shallow soil frost treatments, compared with the other treatments. Explorative multivariate analyses indicate that increasing soil frost is contributing to increased protein‐like fluorescence and to increased biological degradability of the DOC. Our study shows that decreases in riparian soil frost due to climate warming may not only contribute to decreased riparian DOC concentrations but also lead to shifts in the DOC composition, resulting in decreased biodegradability (yet similar photodegradability) of the DOC that is exported from riparian soils to streams.
Bacterial Fe(II) oxidation distinguished by long‐range correlation in redox potential
Authors: Enright Allison M. L. , Ferris F. Grant 
Published: March 2016

AbstractThe kinetics of bacterial Fe(II) oxidation was investigated 297 m underground at the Äspö Hard Rock Laboratory (near Oskarshamn, Sweden) under steady state groundwater flow conditions in a flow‐through cell containing well‐developed flocculent mats of bacteriogenic iron oxides (BIOS). Pseudo first‐order rate constants of 0.004 min−1 and 0.009 min−1 were obtained for chemical and bacterial Fe(II) oxidation, respectively, based on the 104 min retention time of groundwater in the flow cell, inlet Fe(II) concentration of 21.0 ± 0.5 µm, outlet Fe(II) concentration of 8.5 ± 0.7 µm, as well as constant pH = − log H+ of 7.42 ± 0.01, dissolved O2 concentration of 0.11 ± 0.01 mg/L, and groundwater temperature of 12.4 ± 0.1°C. Redox potential was lower at the BIOS‐free inlet (−135.4 ± 1.16 mV) compared to inside BIOS within the flow cell (−112.6 ± 1.91 mV), consistent with the Nernst relationship and oxidation of Fe(II) to Fe(III). Further evaluation of the redox potential time series data using detrended fluctuation analysis (DFA) revealed power law scaling in the amplitude of fluctuations over increasing intervals of time with significantly different (p < 0.01) DFA α scaling exponents of 1.89 ± 0.03 for BIOS and 1.67 ± 0.06 at the inlet. These α values not only signal the presence of long‐range correlation in the redox potential time series measurements but also distinguish between the slower rate of chemical Fe(II) oxidation at the inlet and faster rate accelerated by FeOB in BIOS.
Asymmetric Organocatalytic Assembly of Oxindoles Fused with Spiro‐3,4‐dihydropyrans with Three Contiguous Stereocenters Consisting of Vicinal Quaternary Centers
Authors: Vishwanath Manjunatha , Vinayagam Poopathy , Gajulapalli V Pratap Reddy , Kesavan Venkitasamy 
Published: March 2016

AbstractDiverse bispiro‐3,4‐dihydropyrans consisting of oxindole moieties with three contiguous chiral centers and vicinal quaternary stereocenters were synthesized with very good yields of up to 92 % and excellent enantioselectivity of up to 99 % ee by using a proline‐derived thiourea organocatalyst.
Application of the relativistic precession model to the accreting milisecond X‐ray pulsar IGR J17511–3057
Authors: Stefanov I. Zh. 
Published: March 2016

AbstractThe observation of a pair of simultaneous twin kHz QPOs in the power density spectrum of a neutron star or a black hole allows its mass‐angular‐momentum relation to be constrained. Situations in which the observed simultaneous pairs are more than one allow the different models of the kHz QPOs to be falsified. Discrepancy between the estimates coming from the different pairs would call the used model into question. In the current paper, the relativistic precession model is applied to the twin kHz QPOs that appear in the light curves of three groups of observations of the accreting millisecond X‐ray pulsar IGR J17511–3057. It was found that the predictions of one of the groups are practically in conflict with the other two. Another interesting result is that the region in which the kHz QPOs have been born is rather broad and extends quite far from the ISCO. (© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Search for hard lags with intra‐night optical observations of BL Lacertae
Authors: Zhang Y. H. , Xu L. , Li J. C. 
Published: March 2016

AbstractIt is generally believed that the high energy end of synchrotron emission, generated by the most energetic tail of relativistic electrons in the jets, account for the X‐ray emission of high‐energy peaked BL Lac objects (HBLs) and the optical emission of intermediate‐energy peaked BL Lac objects (IBLs). It is thus expected that both should show similar variability characteristics. One of the important variability parameters is the inter‐band time lag which probes the acceleration and cooling of relativistic particles responsible for the emission. The switches between soft and hard lags have been detected in the intra‐day X‐ray variability of a few HBLs, which is not the case for the intra‐day optical variability of IBLs yet. We present the results of our intra‐night optical observations for BL Lacertae, aiming at searching for hard lags of its optical variations, performed with the 80 cm telescope in fourteen nights of 2010 September‐November. Intra‐night changes of ∼0.2 mag were detected in most of nights. The intra‐night variability amplitude tends to become larger from red to blue wavelength, and the optical spectrum hardens with increasing brightness. The intra‐night variations correlate between different wavebands, but we did not find significant time lags, either soft or hard. Nevertheless, on November 2, the B band variations showed a sign of lagging the R band ones by 317±214 s. The claim of this hard lag is strongly limited by the photometric precision and time resolution. Therefore, the switches between soft and hard lags of IBLs in the optical bands needs further demonstration with more higher quality observations. (© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Analysis of gene expression for microminipig liver transcriptomes using parallel long‐read technology and short‐read sequencing
Authors: Sakai Chizuka , Iwano Shunsuke , Shimizu Makiko , Onodera Jun , Uchida Masashi , Sakurada Eri , Yamazaki Yuri , Asaoka Yoshiji , Imura Naoko , Uno Yasuhiro , Murayama Norie , Hayashi Ryoji , Yamazaki Hiroshi , Miyamoto Yohei 
Published: March 2016

AbstractThe microminipig is one of the smallest minipigs that has emerged as a possible experimental animal model, because it shares many anatomical and/or physiological similarities with humans, including the coronary artery distribution in the heart, the digestive physiology, the kidney size and its structure, and so on. However, information on gene expression profiles, including those on drug‐metabolizing phase I and II enzymes, in the microminipig is limited. Therefore, the aim of the present study was to identify transcripts in microminipig livers and to determine gene expression profiles. De novo assembly and expression analyses of microminipig transcripts were conducted with liver samples from three male and three female microminipigs using parallel long‐read and short‐read sequencing technologies. After unique sequences had been automatically aligned by assembling software, the mean contig length of 50843 transcripts was 707 bp. The expression profiles of cytochrome P450 (P450) 1A2, 2C, 2E1 and 3A genes in livers in microminipigs were similar to those in humans. Liver carboxylesterase (CES) precursor, liver CES‐like, UDP‐glucuronosyltransferase (UGT) 2C1‐like, amine sulfotransferase (SULT)‐like, N‐acetyltransferases (NAT8) and glutathione S‐transferase (GST) A2 genes, which are relatively unknown genes in pigs and/or humans, were expressed strongly. Furthermore, no significant gender differences were observed in the gene expression profiles of phase I enzymes, whereas UGT2B17, SULT1E1, SULT2A1, amine SULT‐like, NAT8 and GSTT4 genes were different between males and females among phase II enzyme genes under the present sample conditions. These results provide a foundation for mechanistic studies and the use of microminipigs as model animals for drug development in the future. Copyright © 2016 John Wiley & Sons, Ltd.
In silico evaluation of warfarin–bucolome therapy
Authors: Ohtani Hisakazu , Hakoda Ryoko , Imaoka Ayuko , Akiyoshi Takeshi 
Published: March 2016

AbstractPurpose: Some reports have suggested that bucolome, an inhibitor of cytochrome P450 2C9, is useful for decreasing inter‐patient variation in warfarin clearance. The purpose of the present study was to evaluate the utility of the concomitant administration of bucolome and warfarin using an in silico approach. Methods: In vitro data regarding the enzymatic kinetics of (S)‐warfarin and bucolome were collected from the literature. As a validation study, the geometric mean (GM) of the oral unbound clearance of (S)‐warfarin and its inter‐patient variation (assessed using the standard deviation of its natural logarithm (σ)) were predicted using a physiologically based population pharmacokinetic simulator (SimcypTM) and compared with clinical data. The utility of the concomitant administration was evaluated by comparing the GM and σ values predicted under various conditions (the prediction study). Results and Discussion: The σ values in the presence and absence of bucolome were predicted to be 0.73 and 0.68, respectively, suggesting that bucolome might increase the inter‐patient variation, as clinically observed. In the prediction study, the σ value of the bucolome co‐administered group was greater in almost all of the examined conditions. In conclusion, the concomitant administration of bucolome might not be useful for reducing the inter‐patient variation of (S)‐warfarin pharmacokinetics. Copyright © 2016 John Wiley & Sons, Ltd.