bluuebunny/crossref_metadata_2025_split huggingface dataset:
Episodic magmatism contributes to sub-seafloor copper mineralization: Insights from textures and geochemistry of zoned pyrite in the Ashele VMS deposit
Authors: Xiao Bing , Chen Huayong , Feng Yuzhou , Pan Yuanming 
Published: September 2024

Abstract
Prolonged and episodic magmatic-hydrothermal processes have been proposed to be important in forming large-tonnage Cu volcanogenic massive sulfide (VMS) deposits but are difficult to document and remain poorly understood in ancient VMS systems. In this study, we combine textural evidence, in situ analysis of sulfur isotopic composition with trace elements of pyrite from the well-preserved, large-tonnage Ashele VMS deposit (Central Asian Orogenic Belt, NW China) to elucidate the origin of the ore-forming materials and controlling factors of VMS deposits. The distribution of hydrothermal alteration and mineralization allows the Ashele deposit to be divided into five zones: massive sulfide, quartz-pyrite, chlorite-chalcopyrite-quartz-pyrite, quartz-chlorite-sericite-pyrite, and quartz-sericite-pyrite zones. Cu mineralization is mainly hosed in the massive sulfide and chlorite-chalcopyrite-quartz-pyrite zones. Three texturally and compositionally distinct types of pyrite from the Cu mineralization zones have been recognized. The first type of growth zones with high Cu, As, and volatile elements (e.g., Hg and Tl) concentrations and negative δ34S values (-7.83‰–-0.35‰) observed in pyrite grains from the massive sulfide zone most likely formed from the input of magmatic volatiles from degassing of the underlying magmatic systems. The second type of Cu-As-rich growth zones in pyrite grains from the chlorite-chalcopyrite-pyrite zone is not enriched in volatile elements and has positive δ34S values (2.59‰–6.56‰), which is interpreted to have precipitated during fluid boiling. The third type of growth zones, without Cu-As enrichment but having positive δ34S values (0.30‰–9.76‰) in pyrite grains from both mineralization zones, was probably formed without boiling or magmatic volatile input. Our results suggest that multi-stage magmatic degassing or fluid boiling accompanied by Cu precipitation recorded in individual pyrite grains can reveal episodic magmatic-hydrothermal activities, which are essential factors in forming large-tonnage VMS deposits.
Climate change impact assessment of growing degree days and thermal growing period of cotton in north-west India
Authors: Kaur Varinderjit , Singh Som Pal , Kingra Pavneet Kaur , Singh Jatinderpal 
Published: September 2024

ABSTRACT

Temperature is an indispensable necessity of plant growth, which explains the 95% variability in plant development. Accumulated temperature, i.e. growing degree day (GDD) is a useful agro-climatic indicator that translates raw climatic data into meaningful decisions. In this study, the GDD concept is used to analyze spatio-temporal variability of accumulated growing degree days (AGDD) and thermal growing period of cotton for the past and future climates in the three different zones (north-east, central and south-west) of Punjab. During the baseline period, higher AGDD were accumulated in the south-western (2,441 °C day), followed by central (2,276.8 °C day) and north-eastern (2,073.8 °C day) zones. During the end of mid-century, AGDD of the central zone was increased by 4–11%, 3–27% for north-eastern, and 3–7% for south-western zones in contrast to the baseline period. This increase in AGDD of cotton might decrease the thermal growing period by 6–14%, 8–25%, and 4–8% for central, north-east and south-western zones, clearly indicating the thermal stress over the cotton crop. This study provides quantitative information for crop breeders and cotton scientists to develop new genetically modified cultivars and improved agronomic practices to mitigate the adverse effect of climate change.
Jim Anchante Arias. El ruiseñor de ultramar: estudio de la vida y obra de Nicanor del la Rocca de Vergalo. Fondo Editorial de la Universidad Nacional Agraria La Molina. 2024
Authors: Silva Guerrero Fernando 
Published: September 2024

Jim Anchante Arias. Jim Anchante Arias ha publicado valiosos trabajos sobre poesía peruana, entre los cuales destacan sus estudios Poesía, ser y quimera (2012) y Las figuras del cazador (2013). Ya en dichos estudios despliega su conocimiento e interés por el tema del símbolo, las figuras literarias y las influencias francesas en la poesía peruana. El ruiseñor de ultramar. Estudio de la vida y obra de Nicanor della Rocca de Vergalo es una contribución más dentro de esta línea de investigación cultivada por Anchante en estos años. Se trata de un estudio surgido de la consulta de importantes materiales que realizó mientras redactaba su tesis doctoral en Francia, y que pretende recuperar para la historia literaria nacional a un autor que gozó de cierta importancia en su época.
Protective Effects of Curcumin against Nephrotoxicity in Male Rats after Chronic Exposure to Chlorpyrifos
Authors: Farkhondeh Tahereh , Roshanravan Babak , Samini Fariborz , Samarghandian Saeed 
Published: September 2024

Background:
Organophosphorus insecticides, widely used in farming and agriculture,
have been associated with various health issues. Curcumin, a natural antioxidant, has
shown potential in mitigating the adverse effects induced by these insecticides.

Aim:
This study aimed to evaluate the nephroprotective effects of Curcumin (CUR) against
Chlorpyrifos (CPF)-induced renal damage.

Method:
Forty male Wistar albino rats were randomly assigned to five groups, each containing
eight rats: control (0.5 mL of olive oil, the solvent for chlorpyrifos), CPF (10 mg/kg of chlorpyrifos),
CPF + CUR 25 mg/kg/day, CPF + CUR 50 mg/kg/day, and CPF + CUR 100 mg/k/day. All
groups were treated for 90 days. Finally, kidney tissue was assessed for oxidative stress, inflammatory
markers, and histopathological changes.

Result:
A considerable elevation in urea and Creatinine (Cr) concentrations was observed in the
CPF group compared to the control rats (p < 0.01). CUR decreased creatinine and urea levels in
the CPF-exposed group compared to the non-CUR-treated animals (p < 0.05). Additionally, the
concentrations of NO, MDA, IL-6, IL-1β, and TNFα were significantly increased in the kidneys
of the CPF-induced rats compared to the controls (p < 0.001). However, CUR (100 mg/kg) administration
significantly reduced the abovementioned parameters in rat kidneys (p < 0.01). CUR
(100 mg/kg) also increased superoxide dismutase activity and glutathione concentration in the
kidneys of CPF-exposed animals compared to non-CUR-treated rats (p < 0.05). Histopathological
analysis revealed severe congestion in the kidney tissue after CPF exposure. However, coadministration
of CUR restored the normal structure of the kidney in the experimental rats.

Conclusion:
Our findings suggest that curcumin, a potent antioxidant, can help alleviate
chlorpyrifos-induced nephrotoxicity.
Delivery of Superoxide Dismutase 3 Gene with Baculoviruses Inhibits TNF-α Triggers Vascular Smooth Muscle Cell Proliferation and Inflammation
Authors: Lin Shoa-Lin , Lee Song-Tay , Huang Shang-En , Chang Tsung-Hsien , Geng Yong-Jian , Sulistyowati Erna , Yeh Jwu-Lai 
Published: September 2024

Background:
Superoxide dismutase 3 (SOD3), recognized as a potent free radical scavenger,
exhibits antioxidant, anti-inflammatory, and anti-angiogenic properties. However, the
molecular mechanisms underlying the protective effects of SOD3 on the vascular smooth muscle
cell during atherosclerosis remain unclear.

Objectives:
This study aimed to investigate the efficacy of the baculovirus expressing SOD3 gene
delivery to vascular smooth muscle cells (VSMCs) and investigate whether the overexpression of
SOD3 mitigates cell proliferation and migration induced by tumor necrosis factor-α (TNF-

Methods:
A baculoviral vector containing SOD3 cDNA (vAcMBac-CMV-IE-SOD3) was constructed
and utilized to deliver the SOD3 gene into primary rat VSMCs. Cells were stimulated
with recombinant TNF-α, and then cell proliferation and migration were evaluated using the bromodeoxyuridine
and wound healing assay. Western blot was used to verify the expression of cell
cycle regulators, cellular mediators, and proliferative biomarkers. Zymography, immunofluorescence
staining, and ELISA assay were conducted to assess the expression levels of matrix metalloproteinases.

Results:
The results demonstrated efficient and non-cytotoxic transduction of vAcMBac-
CMV-IE-SOD3 in VSMCs. SOD3 overexpression significantly suppressed cell proliferation
and motility by inhibiting cell cycle regulators in TNF-α-induced cells. TNF-α elevated protein
levels of phospho-ERK and phospho-Akt were reduced markedly by SOD3-overexpressing. Additionally,
SOD3 overexpression attenuated the elevation of MMP-2 and MMP-9, the pro-inflammatory
and proliferative biomarkers. Overall, the SOD3 gene delivery exhibited potent anti-proliferation
and anti-inflammation effects on TNF-α-induced VSMCs.

Conclusion:
An effective SOD3 gene delivery using a recombinant baculoviral vector has been
successfully established and is useful for overexpression of the SOD gene family. This approach
provides new therapeutic strategies in gene therapy against atherosclerosis.
In Silico Studies of Phytoconstituents to Identify Potential Inhibitors for ERα Protein of Breast Cancer
Authors: Alagarsamy Veerachamy , Sulthana Mohaideen Thasthagir , Narendhar Bandi , Solomon Viswas Raja , Parthiban Periyasamy , Satishchandra Aithamraju , Jothi Lalkote Aruna , Murugesan Sankaranarayanan 
Published: September 2024

Background:
It is noteworthy that a wide array of plants and nutraceuticals are effectively
utilized in the treatment of various cancers, demonstrating potent effects on different cancer
targets with fewer side effects. Notably, estrogen alpha has been identified as a crucial factor in
breast cancer cell proliferation. Agents that can antagonize its action hold promise as potential drug
leads for the treatment of breast cancer.

Objective:
This study aims to discover and identify the potential inhibitors against the most influential
ERα receptor by the computational approach of 134 phytochemicals from 17 medicinal plants
by using in silico docking studies.

Methods:
The molecular docking was performed by a genetic algorithm using the Auto Dock Vina
program, and the validation of docking was also performed by using Molecular Dynamic (MD)
simulation by the Desmond tool of Schrödinger molecular modeling. Drug-likeness properties and
toxicity studies were conducted using SWISS PRO.

Results:
The top ten highest binding energy phytochemicals ginicidin (-10.8 kcal/mol), lemairone
(-10.5 kcal/mol), ixoratannin (-10.0 kcal/mol), hydnocarpine (-9.8 kcal/mol), arabelline (-9.8
kcal/mol), acutilobine E (-9.8 kcal/mol), chaparinone (-8.9 kcal/mol), plumieride coumerate (-8.8
kcal/mol), acutilobine C (-8.7 kcal/mol), and mezerein (-8.7 kcal/mol) were taken for drug-likeness
test and ADMET profile prediction with the help of web-based server SWISS ADME and protoxII.
Docking's study dictated that ten phytochemical constituents showed greater binding interactions
than standard tamoxifen (-6.6 kcal/mol) towards the target protein ERα. MSD study was achieved
for the most active 4 phytoconstituents, and the stability of the ligand-protein complex was confirmed
and showed that all the four compounds possess comparatively stable ligand-protein complexes
with ERα target as compared to the tamoxifen-ERα complex.

Conclusion:
Among the top ten phytochemicals, ginicidin (glycoside) formed a more stable complex
and had greater binding affinity than standard tamoxifen with better safety profiles. Hence,
this compound can be further studied for lead optimization and drug development for the treatment
of breast cancer.
Pengaruh Social Media Influencer Dan Brand Image Terhadap Purchasing Decision
Authors: Ramadhana Muhammad Raihan , Pradana Bayu Ilham 
Published: September 2024

This research aims to determine the effect of social media influencer and brand image on purchasing decision Case study Instagram’s followers @kahfeveryday. This type of research is a quantitative research that aims to find a causal relationship between social media influencer, brand image, and purchasing decision. This research using 100 respondents as the sample from instagram’s followers @kahfeveryday. Sampling used a non-probability sampling technique, namely purposive sampling. The characteristic of the respondents must be over 17 years old, ever bought a Kahf product, and have seen instagram post of @kahfeveryday minimum 1 time. The data analytic in this research is using Multiple Linear Regression which supported by Validity Test, Reliability Test, and Classical Assumption Test. Hypothesis Test in this research was carried out using F-Test and t-Test using software SPSS 26. The result of this research are variable social media influencer and brand image had a significant effect on purchasing decision.

Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh social media influencer dan brand image terhadap purchasing decision pada followers Instagram @kahfeveryday. Jenis penelitian ini adalah penelitian kuantitatif dengan tujuan mengetahui hubungan sebab akibat antara variabel social media influencer, brand image, dan purchasing decision. Penelitian ini menggunakan sampel sebanyak 100 responden yang diambil dari followers Instagram @kahfeveryday. Pengambilan sampel menggunakan Teknik non-probability sampling yaitu purposive sampling. Karakteristik sampel yang di pilih yaitu berusia lebih dari 17 tahun, pernah membeli produk dari Brand Kahf, dan pernah melihat postingan Instagram @kahfeveryday minimal 1 kali. Teknik analisis yang digunakan dalam penelitian ini adalah Regresi Linear Berganda yang didukung dengan Uji Validitas, Uji Reliabilitas dan Uji Asumsi Klasik. Uji hipotesis yang dilakukan dalam penelitian ini adalah Uji F dan Uji-t menggunakan software SPSS 26. Hasil penelitian menunjukkan bahwa variable social media influencer dan brand image berpengaruh signifikan terhadap purchasing decision.
The Influence of Motivation and Service Quality Towards Customer Satisfaction
Authors: Rafiqi Idham Ramdan 
Published: September 2024

This study aims to determine the impact of motivation and service quality on the customer satisfaction of participants in the Jakarta Cheetahs After Hour program. The research adopts an explanatory approach employing a quantitative method. Non-probability sampling techniques, specifically the purposive sampling method, were utilized, and the sample comprised 200 respondents. The inclusion criteria for respondents were a minimum age of 17 years and current or past participation in the Jakarta Cheetahs After Hour program. Measurement of items in the questionnaire was conducted using the Likert scale, assigning scores from 1 to 5. The Statistical Package for the Social Sciences (SPSS) was employed for the validity test, reliability test, and classical assumption test. Data analysis techniques included the multiple linear regression test and the coefficient of determination test. Hypothesis testing in this study involved partial hypothesis testing. The findings of this study indicate that the variable of Motivation (X1) has a positive influence on Customer Satisfaction (Y). Additionally, Service Quality (X2) was found to significantly impact Customer Satisfaction (Y).

Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh motivasi dan kualitas pelayanan terhadap kepuasan pelanggan Partisipan Jakarta Cheetahs After Hour. Jenis penelitian ini merupakan explanatory research dengan metode kuantitatif. Penelitian ini menggunakan teknik nonprobability sampling dengan metode purposive sampling dan menggunakan sampel sebanyak 200 responden. Kriteria yang dibutuhkan responden dalam penelitian ini adalah berusia minimal 17 tahun dan pernah atau sedang mengikuti Jakarta Cheetahs After Hour. Pengukuran yang digunakan sebagai nilai item pertanyaan dalam kuesioner adalah Likert scale dengan skor 1-5. Penelitian ini menggunakan Statistical Package for the Social Sciences (SPSS) untuk melakukan uji validitas, uji reliabilitas, dan uji asumsi klasik. Sedangkan teknik analisis data yang digunakan dalam penelitian ini adalah uji regresi linier berganda dan uji koefisien determinasi. Uji hipotesis yang dilakukan dalam penelitian ini adalah uji hipotesis secara parsial. Temuan penelitian ini menunjukkan bahwa variabel Motivasi (X1) berpengaruh positif terhadap Kepuasan Pelanggan (Y), sedangkan Kualitas Pelayanan (X2) berpengaruh signifikan terhadap Kepuasan Pelanggan (Y).
Nghiên cứu thành phần tuyến trùng ký sinh thực vật trên cây đậu phộng (Arachis hypogaea) tại tỉnh Trà Vinh
Authors: Nguyễn Gia Huy , Nguyễn Thị Thu Nga , Trần Vũ Phến , Nguyễn Văn Hòa 
Published: September 2024

Thành phần tuyến trùng ký sinh thực vật (PPNs) liên quan đến cây đậu phộng được thực hiện tại các huyện Duyên Hải, Cầu Ngang và Trà Cú, tỉnh Trà Vinh. Phương pháp nghiên cứu dựa vào đặc điểm hình thái học và các chỉ số đo về hình thái lượng kết hợp một số chỉ số đánh giá đặc điểm sinh học quần xã trong đất. Kết quả khảo sát đã ghi nhận được 17 loài, 10 giống PPNs thuộc 8 họ bao gồm: Pratylenchus coffeae, P. brachyurus, Ditylenchus ausafi, Helicotylenchus crenacauda, Hirschmanniella oryzae, H. mucronata, Mesocriconema curvatum, M. ornatum, Mesocriconema sp., Meloidogyne graminicola, Tylenchorhynchus leviterminalis, T. mashhoodi, T. nudus, T. annulatus, Tylenchus sp., Longidorus elongatus và Xiphinema elongatum. Trong đó, tần suất hiện diện của giống Mesocriconema phổ biến trên nhóm đất cát chiếm 100% và đã ghi nhận sự xuất hiện của 3 giống Pratylenchus, Tylenchorhynchus và Hirschmanniella trong rễ cây đậu phộng; đồng thời đã ghi nhận sự hiện diện của giống tuyến trùng Pratylenchus phổ biến trong trái đậu phộng có triệu chứng đốm đen. Hai giống Mesocriconema và Pratylenchus tìm thấy trong nghiên cứu này là tác nhân ký sinh quan trọng trên cây đậu phộng và cần tiến hành các biện pháp phòng trừ.
Implementasi Standard Operating Procedure Resepsionis Dalam Melakukan Check-In dan Check-Out
Authors: Sintyawati Ni Wayan , Suwintari I Gusti Ayu Eka 
Published: September 2024

Penelitian ini dilakukan pada bagian Front Office Department. Studi ini dilakukukan untuk mengetahui bagaimana implementasi standard operating procedure resepsionis dalam melakukan check-in dan check-out di Amandari Resort Ubud. Penelitian ini dilatar belakangi karena masih didapati tamu yang kebingungan dengan informasi mengenai hotel yang seharusnya sudah mereka ketahui setelah melakukan proses check-in. Dan juga sering didapati barang tamu yang ketinggalan pada saat melakukan proses check-out. Alat ukur yang digunakan untuk mengetahui bagaimana implementasi standard operating procedure resepsionis dalam melakukan check-in dan check-out adalah dengan melakukan observasi dan wawancara. Wawancara ini dilakukan langsung dengan Ibu Agung Asrami selaku Front Office Supervisor di Amandari Resort Ubud. Data yang digunakan pada penelitian ini adalah data kualitatif, data yang tidak berupa angka tetapi data yang berupa keterangan. Hasil dari penelitian ini menyatakan bahwa implementasi standard operating procedure sudah diterapkan dengan cukup baik, namun terdapat beberapa prosedur yang jarang diterapkan dikarenakan keterbatas waktu dan juga selalu menyesuaikan dengan kedaan dan juga kondisi dilapangan.

This research was conducted in the Front Office Department. This study was conducted to determine how the implementation of receptionist standard operating procedures in checking in and check-out at Amandari Resort Ubud. This research is motivated because there are still guests who are confused with information about the hotel that they should have known after the check-in process. And also often found guest items that are missed during the check-out process. The measuring tool used to determine how the implementation of the receptionist's standard operating procedure in checking in and check-out is by observing and interviewing. This interview was conducted directly with Ibu Agung Asrami as Front Office Supervisor at Amandari Resort Ubud. The data used in this study is qualitative data, data that is not in the form of numbers but data in the form of information. The results of this study show that the implementation of standard operating procedures has been implemented quite well, but there are some procedures that are rarely applied due to time constraints and also adjust to the situation and also conditions in the field.
O Dendê, a Bahia, as políticas de desenvolvimento, o racismo e seus paradoxos
Authors: Souza dos Santos André 
Published: September 2024

Este artigo se propõe a analisar principalmente o fenômeno de escasseamento na produção de azeite de dendê da espécie Dura (que é originalmente africano) na Bahia; trata dos problemas agrários e agrícolas da Costa do Dendê no Baixo Sul baiano e do seu esquecimento nos processos de financiamento agrícola e desenvolvimento tecnológico. Desde de 2021 a escassez do óleo, tão precioso em tantas esferas culturais e comerciais na Bahia vem causando bastante discussão entre povos de santo, as baianas de acarajé, restaurantes, produtores rurais, intelectuais e a imprensa baiana. A possibilidade de uma redução permanente das quantidades disponíveis do azeite de dendê vem deixando aqueles que precisam dele em seus rituais e na sua culinária muito preocupados. Talvez possa se partir do pressuposto de que o azeite de dendê representa muito pouco ou quase nada para a Bahia, pelo menos em matéria de consciência pública, e uma vez estabelecido o paradoxo, determinar que o dendê representa a Bahia em sua totalidade! O fato de estar chegando ao limite da sua sustentabilidade, demostra a negligencia e o esquecimento de políticas públicas em seus processos de desenvolvimento na maneira como historicamente ele vem sendo tratado.
Arte e saúde: expressão do cuidar/cuidado humano em uma pintura da Renascença
Authors: Da Silva Lima Leidson , Dias Ferreira Edson , Vasconcelos de Oliveira Margarida Maria 
Published: September 2024

RESUMO

Este artigo apresenta informações de um estudo iconográfico – pautado no campo da abordagem qualitativa, orientado pela questão “quais as representações do cuidar/cuidado humano presentes em uma pintura da Renascença?” – cujo objetivo foi identificar a(s) representação(ões) do cuidar/cuidado humano expressa(s) por uma pintura renascentista. A arte desenvolvida no Renascimento teve um caráter científico devido aos conhecimentos da Matemática, Física, e outras áreas, inseridos nela. Os resultados do estudo da imagem produzida por material artístico – iconografia – permitiram, através da análise iconográfica, desvelar o cuidar/cuidado humano sob a forma de compaixão como sendo o verdadeiro significado da pintura O Bom Samaritano (1550-1570) de Jacopo Bassano. Outras variantes de cuidar/cuidado foram identificadas, confluindo para a representação do cuidar/cuidado manifestação da vida.

Palavras-chave: Arte, saúde, cuidar/cuidado humano, Renascimento, iconografia