bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Studies of a MODIS-Based Potential Evapotranspiration Input to the Sacramento Soil Moisture Accounting Model
Authors: Bowman Angela L. , Franz Kristie J. , Hogue Terri S. 
Published: November 2016

Abstract
A satellite-based potential evapotranspiration (PET) estimate derived from Moderate Resolution Imaging Spectroradiometer (MODIS) observations was tested for input to the spatially lumped and gridded Sacramento Soil Moisture Accounting (SAC-SMA) model. The 15 forecast points within the National Weather Service (NWS) North Central River Forecast Center (NCRFC) forecasting region were the basis for this analysis. Through a series of case studies, the MODIS-derived PET estimate (M-PET) was evaluated for input to the SAC-SMA model by comparing streamflow simulations with those from traditional SAC-SMA evapotranspiration (ET) demand. Two prior studies have evaluated the M-PET data 1) to compute new long-term average ET demand values and 2) to input a time series (i.e., daily time-varying PET) to the NWS Hydrology Laboratory–Research Distributed Hydrologic Model (HL-RDHM), a spatially distributed version of the SAC-SMA model. This current paper presents results from a third test in which the M-PET time series is input to the lumped SAC-SMA model. In all cases, evaluation is between the M-PET data and the long-term average values used by the NWS. Similar to prior studies, results of the current analysis are mixed with improved model evaluation statistics for 4 of 15 basins tested. Of the three cases, using the time-varying M-PET as input to the distributed SAC-SMA model led to the most promising results, with model simulations that are at least as good as those when using the SAC-SMA ET demand. Analyses of the model-simulated ET suggest that the time-varying M-PET input may produce a more physically realistic representation of ET processes in both the lumped and distributed versions of the SAC-SMA model.
What do we need to consider when planning, implementing and researching the use of alternatives to face-to-face consultations in primary healthcare?
Authors: Atherton Helen , Ziebland Sue 
Published: November 2016

Objectives Communications technologies are variably utilised in healthcare. Policymakers globally have espoused the potential benefits of alternatives to face-to-face consultations, but research is in its infancy. The aim of this essay is to provide thinking tools for policymakers, practitioners and researchers who are involved in planning, implementing and evaluating alternative forms of consultation in primary care. Methods We draw on preparations for a focussed ethnographic study being conducted in eight general practice settings in the UK, knowledge of the literature, qualitative social science and Cochrane reviews. In this essay we consider different types of patients, and also reflect on how the work, practice and professional identities of different members of staff in primary care might be affected. Results Elements of practice are inevitably lost when consultations are no longer face-to-face, and we know little about the impact on core aspects of the primary care relationship. Resistance to change is normal and concerns about the introduction of alternative methods of consultation are often expressed using proxy reasons; for example, concerns about patient safety. Any planning or research in the field of new technologies should be attuned to the potential for unintended consequences. Conclusions Implementation of alternatives to the face-to-face consultation is more likely to succeed if approached as co-designed initiatives that start with the least controversial and most promising changes for the practice. Researchers and evaluators should explore actual experiences of the different consultation types amongst patients and the primary care team rather than hypothetical perspectives.
How I treat FLT3-mutated AML
Authors: Pratz Keith W. , Levis Mark 
Published: November 2016

Abstract
FLT3-mutated acute myeloid leukemia (AML), despite not being recognized as a distinct entity in the World Health Organization (WHO) classification system, is readily recognized as a particular challenge by clinical specialists who treat acute leukemia. This is especially true with regards to the patients harboring the most common type of FLT3 mutation, the internal tandem duplication (FLT3-ITD) mutation. Here we present 4 patient cases from our institution and discuss how our management reflects what we have learned about this subtype of the disease. We also reflect on how we anticipate the management might change in the near future, with the emergence of clinically useful tyrosine kinase inhibitors.
A statistical model for the analysis of beta values in DNA methylation studies
Authors: Weinhold Leonie , Wahl Simone , Pechlivanis Sonali , Hoffmann Per , Schmid Matthias 
Published: November 2016

Abstract
Background
The analysis of DNA methylation is a key component in the development of personalized treatment approaches. A common way to measure DNA methylation is the calculation of beta values, which are bounded variables of the form M/(M+U) that are generated by Illumina’s 450k BeadChip array. The statistical analysis of beta values is considered to be challenging, as traditional methods for the analysis of bounded variables, such as M-value regression and beta regression, are based on regularity assumptions that are often too strong to adequately describe the distribution of beta values.

Results
We develop a statistical model for the analysis of beta values that is derived from a bivariate gamma distribution for the signal intensities M and U. By allowing for possible correlations between M and U, the proposed model explicitly takes into account the data-generating process underlying the calculation of beta values. Using simulated data and a real sample of DNA methylation data from the Heinz Nixdorf Recall cohort study, we demonstrate that the proposed model fits our data significantly better than beta regression and M-value regression.

Conclusion
The proposed model contributes to an improved identification of associations between beta values and covariates such as clinical variables and lifestyle factors in epigenome-wide association studies. It is as easy to apply to a sample of beta values as beta regression and M-value regression.
Comparative analysis of economic efficiency of Polish and German listed companies
Authors: Sajnóg Artur 
Published: November 2016

The main subject of theoretical-empirical study presented in this paper is economic efficiency of companies listed on the Polish and German capital market. The discussed research problem was investigated in the form of a comparative analysis and realized in two parts. The discussion presented in the first part depicts mainly theoretical reflections on the essence and assessment measures of companies’ economic efficiency. The second part presents the results of a comparative empirical research on economic efficiency of the companies listed on the Warsaw Stock Exchange and included in the WIG30 index as well as the companies listed on the Frankfurt Stock Exchange, which belong to the DAX index. The research period comprises years between 2004-2013. A comparative analysis of economic efficiency of the companies was conducted using a traditional ratio analysis and the nonparametric DEA method. The results of the empirical research confirm that German companies achieved significantly higher values of basic economic categories in the analysed decade, financial results in particular; however, their generated profits did not reflect in higher values of profitability ratios. Polish companies performed much better as they also showed higher efficiency from the DEA’s point of view.
Pro-investment local policies in the area of real estate economics – similarities and differences in the strategies used by communes
Authors: Małkowska Agnieszka , Głuszak Michał 
Published: November 2016

In the article we discuss the importance of the real estate related instruments used by local government to attract investment and stimulate local economic development. The article discusses economic literature related to public economics at the local government level, with the special emphasis put on the link between urban and real estate economics and development. In the empirical part of the paper, we analyze the results of the survey conducted at the local government level in Poland (Malopolska). There are two major research objectives: (1) to identify the scope of the real estate economic instruments used by the communes as part of their development policies’ strategies; (2) to examine the coexistence of certain types of instruments as part of the commune development strategies. To find relevant answers, both multidimensional scaling and cluster analysis are applied. Additionally, we discuss whether there are evidence of mimicking behavior in local development policies.
Innovation in contemporary economies
Authors: Pohulak-Żołędowska Elżbieta 
Published: November 2016

The hereby article discusses the issues related to the existing or required support given by the State to enterprises in order to provide them conditions to innovate. Neoclassical economy puts an emphasis to the price mechanism as a decision making effective tool, but enterprises meet many barriers in creating and introducing innovation, like high cost, high risk or lack of demand for innovation. These phenomena tend to inhibit innovation of enterprises. This means that market is not an efficient mechanism for innovation activity of enterprises, and its imperfections provoke the State’s intervention. The goal of the article is to shape the objectives of State’s impact on decisions of innovative enterprises. Research method is the critical literature review and public data on State’s support on business R&D analysis. The research results show State’s support for both – incremental and radical innovation, which proves that innovative activity of enterprises is far from being a spontaneous, market-based process.
Biomarkers and Genetics in Peripheral Artery Disease
Authors: Hazarika Surovi , Annex Brian H 
Published: November 2016

AbstractBACKGROUNDPeripheral artery disease (PAD) is highly prevalent and there is considerable diversity in the initial clinical manifestation and disease progression among individuals. Currently, there is no ideal biomarker to screen for PAD, to risk stratify patients with PAD, or to monitor therapeutic response to revascularization procedures. Advances in human genetics have markedly enhanced the ability to develop novel diagnostic and therapeutic approaches across a host of human diseases, but such developments in the field of PAD are lagging.CONTENTIn this article, we will discuss the epidemiology, traditional risk factors for, and clinical presentations of PAD. We will discuss the possible role of genetic factors and gene–environment interactions in the development and/or progression of PAD. We will further explore future avenues through which genetic advances can be used to better our understanding of the pathophysiology of PAD and potentially find newer therapeutic targets. We will discuss the potential role of biomarkers in identifying patients at risk for PAD and for risk stratifying patients with PAD, and novel approaches to identification of reliable biomarkers in PAD.SUMMARYThe exponential growth of genetic tools and newer technologies provides opportunities to investigate and identify newer pathways in the development and progression of PAD, and thereby in the identification of newer biomarkers and therapies.
Reviews
Authors: Simpson Hyacinth , Scafe Suzanne 
Published: November 2016

Abstract
WRITING JAMAICA, ONCE AGAIN OLIVE SENIOR’S THE PAIN TREE (2015) Toronto: Cormorant Books, 194 pp., ISBN: 9781770864344, p/bk, $22.95
COMMUNITIES IN CONTEMPORARY ANGLOPHONE CARIBBEAN SHORT STORIES, LUCY EVANS (2014) Liverpool: Liverpool University Press, 240 pp., ISBN: 9781781381182, h/bk, £75
‘Old Age Has No Remedy’: Selected narratives on the aged and ageing in Barbara Jenkins’ Sic Transit Wagon and Other Stories
Authors: Skeete Geraldine Elizabeth 
Published: November 2016

Abstract
A particular voice in Caribbean women’s short-fiction writing stands out, not only because of the talent and skill displayed by the author and by the numerous awards bestowed upon her, but also because Barbara Jenkins is a septuagenarian who in 2013 published her debut collection Sic Transit Wagon and Other Stories. Her age makes her distinctive among her younger peers who are contributing to a literary renaissance in Trinidad and Tobago. This article explores Jenkins’ positioning as a successful older writer as well as two of her short narratives on marriage, family and health as they relate to older characters. Theories on intelligence, creativity and achievement regarding age and ageing, and the socio-political situation related to the aged in Trinidad and Tobago, are discussed to contextualize Jenkins’ success and the foci of the narratives. This article examines particular discourse strategies used in the two selected stories, as well as themes of marital infidelity, and the impact of age-related disease on spousal and filial relationships.
Ambient horror: From sonic palimpsests to haptic sonority in the cinema of Kurosawa Kiyoshi
Authors: Brown Steven T. 
Published: November 2016

Abstract
In ‘Ambient horror: From sonic palimpsests to haptic sonority in the cinema of Kurosawa Kiyoshi’, Steven T. Brown explores how sound flows modulate affective states and noncognitive responses to the ambient horror films of J-horror maestro Kurosawa Kiyoshi. This article considers elements such as the interrelations between noise and silence, the function of ambient drones and sonic palimpsests, and uses advanced spectral and surround field techniques to analyse sound design. Considering these elements, along with the status of the acousmatic voice, we gain a better understanding of how soundscapes contribute to the construction of horror as a space for what Brown calls ‘haptic sonority’. Haptic sonority is a liminal space that blurs the boundaries between the sonic and the tactile, and compels the audience to bear witness to the embodied effects of sound waves vibrating bodies as if they were resonance chambers. In horror cinema, such haptic sonority opens an intensive space where one does not so much hear sounds as one feels them in one’s body in ways that are by turns bone-rattling, gut-wrenching, and hair-raising. It is here that film touches our bodies and invites us to enter into composition with the micropolitics of sound as resonant subjects in a ‘cinema of sensations’.
A cry in the dark: The howls of wolves in horror and heavy metal music
Authors: Digioia Amanda 
Published: November 2016

Abstract
Deranged howling is a hallmark of wolves, horror texts and heavy metal music artists. This article discusses how wolves, heavy metal music artists and horror text directors use diegetic sound to interact with listeners. Wolves use howls in real life to communicate their location and identity to their pack-mates. Howling in heavy metal music is used either as a literal sound or as a metaphor, to unite their audiences as one cohesive pack, or as a reunion call. The sound of a wolf in horror films indicates something wicked coming along, often in the form of a werewolf or other nefarious monsters. This article shows how a cry in the dark in horror texts, heavy metal music, and in the wilderness is a means of communicating an emotion or identity to a mass human or lupine audience.
A telegraph for China: The attempted application of Caselli’s pantelegraph to transmit Chinese characters, 1856−87
Authors: Vinci Renata 
Published: November 2016

Abstract
In 1872 the Shanghai-based newspaper Shenbao described an invention by Giovanni Caselli that allowed the production of telegraphic messages containing Chinese characters, the ‘pantelegraph’, an ancestor of the fax, reproducing manuscripts, images and symbols, and, as such, totally suitable for Chinese telegraphy. In 1863, the Italian inventor had shown his invention to a legation of Chinese diplomats in France, producing some impressive Chinese transmissions, the caselligrammi. The envoys reported this information back home, but for some reasons a commercial contact was only set twenty years later. Although in many ways this seemed to be a perfectly suitable solution for the telegraphic communication in Chinese, it was never applied in China and the reasons are revealed by a recently discovered account of the Italian Minister Plenipotentiary in China at that time, Ferdinando De Luca, which Caselli himself had copied and saved. The aim of this article is to explore a moment of Chinese and western media history that, to this day, remains relatively unknown. It will discuss an original example of western communication technology and the attempts that were made to lead for its application in China, revealing its strong points and the reasons that ultimately led to its failure.
Energy management and energy accounting<p>Enerji yönetimi ve enerji muhasebesi
Authors: Kırlı Mustafa , Kulu Tekmez 
Published: November 2016

That the energy, as an important production factor, is a non-replaced element is an undeniable fact while the businesses perform their basic functions. In macro scale the economies of the countries and in micro scale businesses must manage the energy well in order to obtain their goals. In that sense, energy management should be organized as an independent unit within the institutions; it should take precautions to reduce the energy costs and to increase the operation productivity of the businesses. In the modern understanding of business administration, energy management has the functions such as reducing the costs in a business, increasing the competitiveness, increasing the operating profits, increasing the operation productivity, wise use of energy and reducing environmental pollution. Energy accounting is an information system that follows, records and reports the energy consumption and energy costs regularly. Energy accounting has a significant contribution in achieving the expected success of energy management. Energy accounting has benefits in many fields such as reducing energy supply costs, reducing energy consumption costs and making budgets of the business in the context of energy management. Energy accounting motivates and activates all the units of the business in terms of reducing energy costs by performing the duties which are expected from it. Özetİşletmeler temel işlevlerini yerine getirirken, önemli bir üretim faktörü olarak enerjinin; ikame edilemeyecek bir unsur olduğu yadsınamaz bir gerçektir. Makro ölçekte ülke ekonomilerinin ve mikro ölçekte de işletmelerin amaçlarına ulaşabilmeleri için enerjiyi etkin bir şekilde yönetmeleri gerekir. Bu bağlamda, enerji yönetimi, kurumlarda bağımsız bir birim olarak örgütlenmeli; enerji maliyetlerini azaltacak ve işletme faaliyet verimliliğini arttıracak önlemleri almalıdır. Çağdaş işletmecilik anlayışında enerji yönetimi; bir işletmede maliyetlerin azaltılması, rekabet gücünün arttırılması, işletme karlılığının arttırılması, işletme verimliliğinin arttırılması, enerjinin akılcı kullanımı ve çevre kirliliğinin azaltılması gibi işlevlere sahiptir. Enerji muhasebesi, enerji tüketimini ve enerji maliyetlerini düzenli bir şekilde izleyen, kaydeden ve raporlayan bir bilgi sistemidir. Enerji yönetiminin kendisinden beklenen başarıyı sağlamasında; enerji muhasebesinin önemli bir katkısı vardır. Enerji muhasebesi, enerji yönetimi kapsamında işletmelere; enerji tedarik maliyetlerini azaltmada, enerji kullanım maliyetlerini azaltmada, işletme bütçelerinin yapılması gibi bir çok alanda faydalar sağlar. Enerji muhasebesi, kendisinden beklenen görevleri yerine getirerek; işletmenin tüm birimlerini, enerji maliyetlerini düşürme konusunda motive etmekte ve harekete geçirmektedir.
Perspectivas didáticas atuais para a matemática no ensino médio
Authors: Dias do Nascimento Shirleyde Dias , Souza Divanizia , Santos Ana Cacia 
Published: November 2016

Esse trabalho teve como objetivo fomentar uma discussão no tocante as perspectivas didáticas atuais para o ensino da matemática no ensino médio a partir das recomendações presentes nos documentos oficiais que fundamentam esse ensino. Buscou-se discutir sobre o tratamento didático, que apontam propostas de currículos a serem desenvolvidas pelas escolas devem incluir competências básicas, conteúdos e formas de tratamento dos conteúdos coerentes com os princípios pedagógicos de identidade, diversidade e autonomia, e também os princípios de interdisciplinaridade e contextualização, adotados como estruturadores do currículo do Ensino Médio. E a posterior por uma análise dos resultados obtidos através de uma investigação para sabermos como a contextualização e a interdisciplinaridade têm sido interpretadas no exercício da prática do docente de matemática; como mobilizam o interesse dos discentes pela matemática como os discentes percebem a importância da matemática e como esperam que seja ensinada. Para tanto, nos reportamos a contribuições teóricas introduzido por Passos (2006), Charlot (2000, 2005 ) e ainda, por Santomé (1998),Tufano (2001), Ole Skovsmose (2001) D´Ambrosio (1989).
Thallium Hyperaccumulation in Polish Populations of Biscutella laevigata (Brassicaceae)
Authors: Wierzbicka Małgorzata , Pielichowska Maria , Abratowska Agnieszka , Wiłkomirski Bogusław , Wysocka Irena , Panufnik-Mędrzycka Dorota , Bulska Ewa 
Published: November 2016

AbstractBiscutella laevigataL. is known as a Tl hyperaccumulator. In PolandBiscutella laevigataoccurs in the Tatra Mts (Western Carpathians) and on the calamine waste heap in Bolesław near Olkusz (Silesian Upland). The purpose of this work was to evaluate whether plants of both populations were able to accumulate an elevated amount of thallium in their tissues. The plants were cultivated in calamine soil in a glasshouse for a season and studied at different ages – from 2-week-old seedlings to 10-month-old adults. Additionally, the plants were grown for ten weeks in calamine soil with EDTA to enhance Tl bioavailability. The total content of Tl in plant tissues after digestion was determined by ICP-MS, whereas its distribution in leaves was studied by LA-ICP-MS. Of the total content of Tl in the soil in the range of (15.2–66.7) mg∙kg−1d.m., only (1.1–2.1) mg∙kg−1d.m. was present in a bioavailable form. The mean content in all the plants grown on the soil without EDTA was 98.5 mg∙kg−1d.m. The largest content was found in leaves – 164.9 mg∙kg−1d.m. (max. 588.2 mg∙kg−1d.m.). In the case of plants grown on the soil enriched with EDTA, the mean content in plants increased to 108.9 mg∙kg−1d.m., max. in leaves – 138.4 mg∙kg−1d.m. (max. 1100 mg∙kg−1d.m.). The translocation factor was 6.1 in the soil and 2.2 in the soil with EDTA; the bioconcentration factor amounted to 10.9 and 5.8, respectively. The plants from both populations did not contain a Tl amount clearly indicating hyperaccumulation (100–500 mg∙kg−1d.m.), however, high (>1) translocation and bioconcentration factors suggest such an ability. It is a characteristic species-wide trait;B. laevigataL. is a facultative Tl hyperaccumulator. The largest Tl amount was located at the leaf base, the smallest at its top. Thallium also occurred in trichomes, which was presented for the first time; in this way plants detoxify Tl in the above-ground parts. Leaves were much more hairy in the Bolesław plants. This is an adaptation for growth in the extreme conditions of the zinc-lead waste heap with elevated Tl quantity.
Stein manifolds of nonnegative curvature
Authors: Chen Xiaoyang 
Published: November 2016

Abstract
Let X bea Stein manifold with an anti-holomorphic involution τ and nonempty compact fixed point set X
τ. We show that X is diffeomorphic to the normal bundle of X
τ provided that X admits a complete Riemannian metric g of nonnegative sectional curvature such that τ*
g = g.