bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sedative and behavioral effects of atomized intranasal midazolam in comparison with nebulized midazolam for children undergoing dental treatment: A randomized clinical trial
Authors: Elkhatib Amira Abdelhafeez , Mowafy Yousr Nader , Ghoneim Tamer A. M. 
Published: September 2024

AbstractBackgroundFear and anxiet are significant barriers of dental care in children. Sedation emerged as a valuable behaviour guidance technique to manage uncooperative children.AimTo evaluate the sedative and behavioral effectiveness of midazolam administered via nebulizer in comparison with intranasal atomizer in the behavior management of anxious children during dental treatment.Study DesignTwo‐arm randomized clinical trial with 68 children (3–5 years) assigned to receive nebulized midazolam (NEB MDZ) and atomized intranasal midazolam (AIN MDZ) during dental treatment. The onset time, sedation levels, and behavior of children were documented. The data were analyzed using the Wilcoxon signed‐rank test and Mann–Whitney U tests.ResultsSignificant differences between the two groups in terms of onset time, sedation level, and behavior of children during the dental treatment. AIN MDZ was associated with a significantly faster onset time compared with NEB MD, (p < .001). Children who received NEB MDZ exhibited deeper levels of sedation compared with AIN MDZ group (p = .02). During the administration of local anesthesia, notable statistical differences were observed between the behavior of the two groups (p = .02).ConclusionsMidazolam administered via either nebulizer or intranasal atomizer was the effective route of administration and proved effective in the management of anxious children undergoing dental treatment. AIN MDZ, however, exhibited a faster onset time, whereas children receiving NEB MDZ demonstrated superior behavior compared with those receiving AIN MDZ.
Platform‐led or seller‐led? Optimal ex ante information delivery strategy for online retail channels with product match uncertainty
Authors: Wang Chen , Fu Yujia , Yin Zhe 
Published: September 2024

AbstractA fundamental weakness for online retail channels is that it is impossible for consumers to perfectly ascertain the match between their preferences and the product value before purchasing. In this paper, based on the investment decision of the ex ante product information delivery measure, we study how to solve this problem for a platform‐based supply chain that consists of an online platform and an online seller. According to which firm is responsible for building the product information delivery measure, two possible cases are considered under a game‐theoretic model: the platform‐led case and the seller‐led case. The basic results reveal that compared with the seller‐led product information delivery, the platform‐led case may lead to a higher matching probability for consumers, a higher profit for the whole supply chain, and a win‐win outcome for the platform and the seller. The basic results can still hold when the platform and the seller cooperate under the format of the proportional commission fee, the two firms have different investment efficiencies in the improvement of product information delivery, or consumers have to incur hassle costs to learn the product match probability. When product return is allowed, it is shown that the return policy can play a positive role in making the seller‐led case become a win‐win choice. When the joint investment of product information delivery between the two firms can be formed, the results show that the joint investment may achieve a higher matching probability and higher profits for both the seller and the platform.
Genomic selection strategies for the German Merino sheep breeding programme – A simulation study
Authors: Martin Rebecca , Pook Torsten , Bennewitz Jörn , Schmid Markus 
Published: September 2024

AbstractGenomic selection is widely implemented in livestock breeding programmes across species. Its potential is also evident for sheep breeding; however, it has several limitations, particularly because of the high genetic diversity across and within sheep breeds. In Germany, the predominant sheep breed is the Merino sheep. Until now, there has been no use of genomic selection in the German Merino sheep breeding programme. In this simulation study, different genomic selection strategies were compared with a reference scenario with a breeding value estimation based on pedigree BLUP. A simplified version of the German Merino sheep breeding programme, including a health and a production trait in the breeding goal, was simulated via the R package Modular Breeding Program Simulator (MoBPS). Real genotype data were used to create a population specific simulation. The reference scenario was compared with several alternative scenarios in which selection was based on single‐step GBLUP (ssGBLUP) breeding value estimation with varying genotyping strategies. In addition to scenarios in which all male and all male plus all female lambs were genotyped, scenarios with a preselection of lambs, that is only a certain proportion (top 25%, top 50%) genotyped, were simulated. The results revealed that genetic gain increased with increasing numbers of available genotypes. However, marginal gains decreased with increasing numbers of genotypes. Compared with the reference scenario, genotyping the top 25% of male lambs increased the genetic gain for the breeding ram population by 13% for both traits whereas genotyping the top 50% of male lambs or all male lambs led to increases of 18% (17%) or 26% (21%) for the health (production) trait, respectively. The potential of genotyping females in addition to male lambs was less evident on the male side with no significant differences between the scenarios with different proportions of genotyped females. The results have shown that genomic selection can be a valuable tool to increase genetic gain in the German Merino sheep population and that the genotyping of a certain proportion of animals might lead to substantial improvement over pedigree‐based breeding value estimation. Nevertheless, further studies, especially economic evaluations, are needed before practical implementation.
Using a Nested Sampling Design Across Spatial Scales to Gain Insights Into Distribution Patterns of Fishes, Mussels and Macroinvertebrates in a Riverine System
Authors: Perez Rocha Mariana , Cottenie Karl , Clein Katherine , Elkins Lindsey , Mangold Rebecca , Nowlin Weston , Perkin Joshuah S. , Wright Kirby , Schwalb Astrid 
Published: September 2024

ABSTRACTAimThe goal of our study was to use a nested sampling design to compare the distribution of different groups of organisms with different dispersal modes and examine their responses in community composition to environmental heterogeneity at different spatial scales (local pool vs. riffle habitat, sections within a river and between rivers).LocationUpper Colorado River basin, Texas, USA.TaxonFishes, mussels and macroinvertebrates.MethodsWe sampled 100 sites using a nested sampling design across five rivers (four tributaries and the mainstem), with four river sections and five sampling sites per section, each consisting of a pool and riffle habitat. Collected data on species abundances, local and landscape environmental variables and spatial variables were analysed using a combination of dissimilarity, redundancy and variation partitioning analysis.ResultsAt the river scale, environmental heterogeneity explained 28% and 34% of the variation in mussel and fish communities, respectively, and 15% for macroinvertebrates. Community changes between sections in the tributaries were highest for fishes, but similarly high for fishes and macroinvertebrates in the mainstem. Significant patterns for mussels were only detected in rivers with higher abundances. No significant differences in dissimilarity were found between mesohabitats, but a small significant effect of mesohabitat was detected for mussels with RDA after removing the river effect.Main ConclusionsAlthough the depauperate mussel communities made it more difficult to draw any conclusions, there were some indications that their distribution was driven by environmental heterogeneity across scales. Section and river scales were relevant for fish, whereas macroinvertebrates showed a weaker response to environmental heterogeneity at these scales. The combination of approaches detected more ecologically meaningful patterns than one analysis alone would have. This study highlights the complexity of riverine community dynamics and underscores the need for a multiscale approach to identify their distribution patterns.
A Multi‐Modelling Approach for Informing the Conservation of a Cold‐Adapted Terrestrial Amphibian in the Face of Climate Change
Authors: Čengić Mirza , Šunje Emina , Bonato Lucio , Van Damme Raoul , Lenders Rob H. J. , Huijbregts Mark A. J. , Lukić Bilela Lada , Schipper Aafke M. 
Published: September 2024

ABSTRACTAimWe aimed to assess potential climate change impacts on the distribution of a cold‐adapted terrestrial amphibian that shows strong intraspecific differentiation.LocationAlps and Dinarides.TaxonAlpine salamander (Salamandra atra).MethodsWe built SDMs for each of two major intraspecific lineages (S. a. atra, which is found throughout the Northern Alps, and S. a. prenjensis, which appears sparsely along the Dinarides) and for the entire species, using occurrence points from a carefully curated database, climate data with 1 km2 spatial resolution and eight modelling techniques. We projected climatically suitable areas to 2070 under two climate scenarios (RCP2.6 and RCP8.5), using 24 general circulation models.ResultsFor S. a. atra, under RCP2.6 scenario, we detected a 3% increase in the extent of climatically suitable areas in the Alps (although with low model agreement), yet a 6% decrease under the RCP8.5 scenario. For S. a. prenjensis, we detected a decrease in the extent of climatically suitable areas in the Dinarides between 7% and 45% (RCP2.6 and RCP8.5, respectively). The SDM predictions for the entire species were most in line with those of the S. a. atra model. Although climate variables were not equally strong in predicting the climatic suitability for both lineages, the minimum temperature of the coldest month revealed an important predictor for the entire species, with clear decreases in suitability towards higher temperature.Main ConclusionsAll models reveal a considerable decrease in climate suitability throughout most of the range of S. atra, which is particularly visible in the Dinarides. We highlight the importance of considering intraspecific variation when modelling climate change impacts on geographically differentiated species whose populations vary in their climatic niche. We provide our study results (occurrence data and maps) via a web application that can be useful for guiding conservation efforts.
A review of latency in the Alloherpesviridae family
Authors: Quijano Cardé Eva Marie , Soto Esteban 
Published: September 2024

AbstractThe ability to impact the immune response of the host has been recognized as essential for the success of a virus during infection. A few groups of viruses can combine these immunomodulatory mechanisms with specific patterns of their own transcriptional and replication regulation to achieve persistence within the host long term. The Herpesvirales order is one of those groups and the resultant state is known as latency. Throughout the years, latency has been studied in many host‐herpesvirus models to attempt to understand the complex and profound effects of this state on the host's systems, and in the hopes of deciphering a way to eliminate the latent state from survivors of the primary infection. Most studies of herpesvirus latency have been conducted on mammalian host species, but this review summarizes the data available regarding herpesviruses in fish species and their latent state. As the field of aquatic animal health research continues to advance, the elucidation of these complex mechanisms will be crucial for disease control, prevention, and treatment.
Metronidazole‐induced encephalopathy with transient cortical lesions
Authors: Takahashi Sunao , Ishihara Shoichiro , Tomimitsu Hiroyuki 
Published: September 2024

AbstractA 65‐year‐old woman developed metronidazole‐induced encephalopathy (MIE) with prolonged severe total aphasia during treatment for a liver abscess. Brain magnetic resonance imaging revealed restricted diffusion in the left cerebral white matter and splenium of the corpus callosum, along with transient cortical lesions but no typical dentate nucleus involvement. Despite discontinuing metronidazole, aphasia persisted for over a month, leading to her death. Although the white matter lesions persisted, the cortical lesions diminished after 2 weeks. This case highlights that MIE can involve the cerebral cortex, similar to Wernicke's encephalopathy.
An autopsy case of MM1‐type sporadic Creutzfeldt–Jakob disease with long survival of 7 years
Authors: Kawanami Aya , Arakawa Akira , Matsubara Tomoyasu , Miyashita Masanobu , Miyagi Yuichi , Hasegawa Kazuko , Murayama Shigeo , Yagishita Saburo , Saito Yuko 
Published: September 2024

AbstractWe report the first autopsy case of MM1‐type sporadic Creutzfeldt–Jakob disease (sCJD) who survived 80 months after long‐term artificial ventilatory support. The cerebral cortex and white matter exhibited severe atrophy, sparing the hippocampus. The prion protein aggregates of 10–20 μm in diameter were prominent. The structure consisted of granulofilamentous profiles. This case provides clues on how MM1‐type sCJD extends pathologically after a long clinical course.
Axial length reduction and choroidal thickening with short‐term exposure to cyan light in human subjects
Authors: Chakraborty Ranjay , Baranton Konogan , Pic Eleonore , Didone Julia , Kim Wanki , Lam Kevin , Papandrea Alessandro , Kousa Jad , Bhasme Tiana , Edmonds Chloe , Trieu Cindy , Chang Eunjong , Coleman Alexander , Hussain Azfira , Lacan Pascale , Spiegel Daniel , Barrau Coralie 
Published: September 2024

AbstractPurposeGiven the potential role of light and its wavelength on ocular growth, this study investigated the effect of short‐term exposure to red, cyan and blue light on ocular biometry in humans.MethodsForty‐four young adults and 20 children, comprising emmetropes and myopes, underwent 2‐h sessions of cyan (507 nm), red (638 nm) and broadband white light on three separate days via light‐emitting glasses. Additionally, young adults were exposed to blue light (454 nm) on an additional day. Axial length (AL) and choroidal thickness (CT) were measured in the right eye before the light exposure (0 min), after 60 and 120 min of exposure and 30 min after light offset using an optical biometer and optical coherence tomographer, respectively.ResultsCompared to broadband light, exposure to red light resulted in a significant increase in AL (mean difference between white and red light at 120 min, +0.007 mm [0.002]), but no significant change in CT, while cyan light caused a significant AL reduction (−0.010 mm [0.003]) and choroidal thickening (+0.008 mm [0.002]) in young adults (p < 0.05). Blue light caused a significant decrease of −0.007 mm (0.002) in young adult eyes at 60 min (p < 0.05). In children, cyan light led to a significant reduction in AL (−0.016 mm [0.004]) and strong sustained choroidal thickening (+0.014 mm [0.004]) compared to broadband light at 120 min (p < 0.05). The effects of cyan light on AL and CT were found to be stronger in myopic young adults and emmetropic children. The opposing effects of red and cyan light on ocular biometry were similar between the two age groups (p > 0.05).ConclusionsExposure to cyan light resulted in AL reduction and choroidal thickening in both young adults and children. Further research is needed to determine the application of these results in developing interventions for myopia control.
Time in hand: Temporal focus in risk discourse and audience emotions on knowledge‐sharing platforms
Authors: Wei Jiuchang , Lu Yiming , Li Yi‐Na 
Published: September 2024

AbstractOnline knowledge‐sharing platforms construct risk knowledge and provide the audience with risk‐related scientific facts. We study how speakers organize narratives in past, present, and future foci to influence the audience's emotions through the audience's appraisal of motive congruency and coping potential. Empirical evidence from 210 Technology, Entertainment, Design talks about disasters from 2002 to 2018 demonstrates that emphasizing the past, present, and future in risk narrative leads to the audience's comments with more negative, less positive, and more positive emotions, respectively. Concrete (vs. abstract) portrayal of the risk narrative improves the audience's situational awareness, enhances their risk appraisal, and intensifies the impact of temporal focus on emotions, providing evidence of how temporal focus impacts. These findings demonstrate that temporal focus can effectively reduce risk overreaction or ignorance and facilitate emotion regulation in risk communication.
Support for collective argumentation in integrated STEM: A study of elementary teachers' practice
Authors: Menke Jenna , Drimalla James , Welji Shaffiq N. , Alibek Aida , Tembe Ngutor , Foutz Tim , Conner AnnaMarie 
Published: September 2024

AbstractArgumentation is an important practice and an explicit goal in educational standards in multiple STEM disciplines. In this descriptive study of elementary teachers' practice, we draw on established frameworks to analyze teacher support for collective argumentation in integrated STEM. We watched over 100 h of video of classroom instruction from 10 elementary teachers and analyzed over 200 episodes of argumentation. We constructed an analytic methodology to categorize integrated STEM tasks, which draws on integrated STEM education literature and selected those teachers from our data who engaged their students in integrated STEM tasks, resulting in an in‐depth analysis of five teachers' practice. We found that the teachers supported students by contributing argument components, using a variety of questions and other supportive actions, and adapting their contributions and supports in different settings. Previous research on collective argumentation has been discipline specific; our study contributes an analysis of teacher support for collective argumentation in integrated STEM.
Study of Eucalyptus pauciflora L. characteristics from Algeria and its impact on the mite affecting honeybees Apis mellifera
Authors: Atmani-Merabet Ghania , Hazmoune Hicham , Fellah Sihem , Belkhiri Abdelmalik 
Published: September 2024

Essential oils play a crucial role in biological control against parasites threatening the beekeeping stock, both in Algeria and globally. Their appropriate use helps reduce the adverse effects of chemical products on human health and the environment. The purpose of this study is to analyze the components of Eucalyptus pauciflora essential oil grown in Algeria and to evaluate its impact on the marine shrimp Artemia salina and the mite Varroa destructor, while also comparing it to other species of Eucalyptus from the same region namely, Eucalyptus robusta, globulus, sideroxylon, and amygdalina, which have been examine in previous research. Steam distillation of fresh leaves from Eucalyptus pauciflora yielded 0.73% essential oils. This plant contains a total of thirty-nine chemical compounds, among which the most significant are 1,8-cineole (57.45%), β-cymene (5.44%), spathulenol (5.38%), trans-verbenol (4.31%), and α-pinene (3.11%). A lethality test on brine shrimp (BSL) revealed that Eucalyptus pauciflora exhibits toxicity with a median lethal concentration (LC50) of 53.51 ppm. Field trials conducted on hives infested with Varroa destructor showed that the acaricidal effect of Eucalyptus pauciflora is superior to that of amygdalina and sideroxylon species, but inferior to that of globulus and robusta species, all sourced from the same herbarium (Draa Naga) in northeastern Algeria. The results of this research highlight the benefits of Eucalyptus essential oils to be integrated into the formulation of natural acaricides that are environmentally friendly to combat Varroa destructor infestation.
Tongues of Fire: Giving Voice to Pentecostal Theology
Authors: Austring Katherine J. , Spencer Archie J. 
Published: September 2024

Abstract
This article is a review and analysis of Frank D. Macchia’s Tongues of Fire: A Systematic Theology of the Christian Faith. The method of our review encompasses two basic principles, that of summary and critical analysis. In the summary sections, our aim is simply to highlight the main features of Macchia’s system. The principle that emerges from this summary is the attempt on Macchia’s part to relate the whole of his system to a “theology of the third article.” The article divides into four parts. Part one establishes Macchia’s general method, with special reference to his appeal to “a theology of the third article.” Parts two and three turn to a basic summary of the main features of the doctrines of God, Christ, Spirit, Church, and Eschatology. Part four is a brief critical analysis that highlights both the successes and questions that have emerged in Macchia’s system.
Legitimising Fishing Port Use in the Information Age: Challenges and Potential in China
Authors: He Juan 
Published: September 2024

Abstract
The Agreement on Port State Measures and follow-up national and regional implementation measures are well-intentioned to build up global resistance to illegal fishing. As the world’s busiest landing and transit hub, China has recently begun to take action to rein in the negative impacts of illegal, unreported and unregulated fishing on its fishing ports. Without treaty ratification and expansive cooperation with other States, that burgeoning effort is nowhere near to greening China’s intrastate and interstate seafood commerce. The widely asserted advantages of information and communication technology signal both an opportunity and challenges for China to overcome its non-ratification and minimal-coordination inertia. Localised and sector-specific trials of electronic monitoring, reporting, and traceability are symbolic of China’s progressive modernisation agenda on fishing port management. Scalability is the next test for electronic port State measures to expand coverage and generate coordinated gains from a holistic closed-loop and information-based paradigm.
Gestes coverbaux et bébé-signes dans l’expression de l’offre et de la requête dans une crèche bilingue
Authors: Azaoui Brahim 
Published: September 2024

Abstract
This paper focuses on the analysis of interactions between three French-speaking children and a Spanish-speaking childcare assistant in a bilingual childcare centre. This study examines how manual gestures (co-speech gestures, emblems and baby-signs) contribute to the expression of offers and requests during mealtimes. The results show that the Spanish-speaking childcare assistant mainly uses baby-signs during mealtimes. These gestures serve several functions, which we present in the article. The findings give rise to a need to revise the current definition and categorisation of baby-signs, and to reflect on how they could fit in Kendon’s continuum.