bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oligonucleotide‐Based Mimetics of Hepatocyte Growth Factor
Authors: Ueki Ryosuke , Ueki Ayaka , Kanda Naoto , Sando Shinsuke 
Published: November 2015

AbstractOligonucleotide‐based hepatocyte growth factor (HGF) mimetics are described. A DNA aptamer to Met, a cognate receptor for HGF, was shown to induce Met activation when used in dimer form. The most potent aptamer dimer, ss‐0, which was composed solely of 100‐mer single‐stranded DNA, exhibited nanomolar potency. Aptamer ss‐0 reproduced HGF‐induced cellular behaviors, including migration and proliferation. The present work sheds light on oligonucleotides as a novel chemical entity for the design of growth factor mimetics.
Investigating the Influence of (Deoxy)fluorination on the Lipophilicity of Non‐UV‐Active Fluorinated Alkanols and Carbohydrates by a New log P Determination Method
Authors: Linclau Bruno , Wang Zhong , Compain Guillaume , Paumelle Vincent , Fontenelle Clement Q. , Wells Neil , Weymouth‐Wilson Alex 
Published: November 2015

AbstractProperty tuning by fluorination is very effective for a number of purposes, and currently increasingly investigated for aliphatic compounds. An important application is lipophilicity (log P) modulation. However, the determination of log P is cumbersome for non‐UV‐active compounds. A new variation of the shake‐flask log P determination method is presented, enabling the measurement of log P for fluorinated compounds with or without UV activity regardless of whether they are hydrophilic or lipophilic. No calibration curves or measurements of compound masses/aliquot volumes are required. With this method, the influence of fluorination on the lipophilicity of fluorinated aliphatic alcohols was determined, and the log P values of fluorinated carbohydrates were measured. Interesting trends and changes, for example, for the dependence on relative stereochemistry, are reported.
Polymeric materials for long‐term durability of photovoltaic systems
Authors: Griffini Gianmarco , Turri Stefano 
Published: November 2015

ABSTRACTPhotovoltaic (PV) technology has evolved rapidly in the past few decades and now encompasses a large variety of materials and device structures. A key aspect to be taken into account in any PV technology is the operational durability of the systems in outdoor conditions. Clearly, loss of performance during operation represents a significant drawback and limitation in the commercialization of this technology. In this context, the large compositional flexibility of polymeric materials as well as their proven easy processability may be of great help in imparting improved durability to PV systems. In this review, a summary on the state of the art and most recent developments in the field of polymeric materials for improved long‐term durability of PV devices is presented, with particular emphasis on the use of polymers as encapsulation materials and protective coatings in the field of both PV and light‐concentration systems. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2016,133, 43080.
Air pollutant emissions inventory of large‐scale production of selected biofuels feedstocks in 2022
Authors: Zhang Yimin , Heath Garvin , Carpenter Alberta , Fisher Noah 
Published: November 2015

AbstractFor climate protection and energy security reasons, biofuels are proposed to replace a significant fraction of fossil transportation fuel. Recognition of differences in production pathways between biofuels and fossil fuels has motivated an emerging literature that considers air quality and human health impacts of potential changes to the magnitude, location, timing, and type of air pollutants emitted. To inform research and development of advanced biofuel production systems as well as air quality management decisions, we have developed a highly resolved inventory of air pollutant emissions for a baseline scenario of current and future US biofuel feedstock production systems using data from recent research. We find that in most US counties, production of cellulosic biofuel feedstocks using advanced practices exhibits lower air pollutant emissions than current corn grain production. An analysis of the contributing sources to each of the seven evaluated air pollutants helps identify emission reduction opportunities. Compared to the 2008 National Emissions Inventory, production of cellulosic biofuel feedstocks to meet regulatory requirements in 2022 typically represents small increments of air emissions, though for certain pollutants and counties, a threshold may be reached whereby further examination may be warranted to ensure air quality standards can be achieved. Given that the advanced biofuel supply chain system is in its infancy, considerable opportunities exist to minimize adverse impacts while maximizing the benefits of advanced biofuels. This analysis enables more informed technology development decisions and identification of mitigation opportunities in the biofuel feedstock production stage. © 2015 Society of Chemical Industry and John Wiley & Sons, Ltd
Renewable Resource‐Based Lubricating Greases from Natural and Synthetic Sources: Insights and Future Challenges
Authors: Abdulbari Hayder A. , Oluwasoga Akindoyo Edward , Mahmood Wafaa K. 
Published: November 2015

AbstractGreases enhance most mechanical equipment in terms of joint performance and operation age by reducing friction and wear. However, they are also considered a dangerous source of soil and water pollution because of their synthetic nature. Renewable resource‐based materials are a safe and environmentally friendly solution. In the present work, a comprehensive study is conducted to evaluate the performance of existing synthetic and biodegradable greases. This work also provides insights into existing literature and presents ideas for future development through general recommendations regarding the use of renewable resource‐based ingredients as a replacement for traditional synthetic materials in conventional greases.
Role of the Metal‐Oxide Support in the Catalytic Activity of Pd Nanoparticles for Ethanol Electrooxidation in Alkaline Media
Authors: Monyoncho Evans Angwenyi , Ntais Spyridon , Brazeau Nicolas , Wu Jhing‐Jhou , Sun Chia‐Liang , Baranova Elena A. 
Published: November 2015

AbstractThe promotional role of oxide supports (CeO2, SnO2, TiO2) on ethanol electrooxidation in alkaline media over Pd nanoparticles (NPs) is presented and compared to Pd on carbon. XPS revealed a shift to lower binding energy of the Pd 3d peak when Pd NPs were deposited on metal oxides, implying a charge transfer from the oxides to the Pd. The catalytic activity of the supported NPs for ethanol electrooxidation was assessed by using cyclic voltammetry and chronoamperometry. The electrooxidation products were monitored in situ, using polarization modulation–infrared reflection absorption spectroscopy (PM‐IRRAS), which revealed that the supports influence the selectivity of reactions on Pd. Pd/CeO2 has superior selectivity towards breaking the C−C bond to produce CO2 compared to the other three supports. Acetate, as a product, was evident on all of the catalysts, but at different ratios. Pd supported on metal oxides showed higher activity and, in particular, CeO2 and SnO2 stand out as the best supports.
Expanding the Scope of Hypervalent Iodine Reagents for Perfluoroalkylation: From Trifluoromethyl to Functionalized Perfluoroethyl
Authors: Matoušek Václav , Václavík Jiří , Hájek Peter , Charpentier Julie , Blastik Zsófia E. , Pietrasiak Ewa , Budinská Alena , Togni Antonio , Beier Petr 
Published: November 2015

AbstractA series of new hypervalent iodine reagents based on the 1,3‐dihydro‐3,3‐dimethyl‐1,2‐benziodoxole and 1,2‐benziodoxol‐3‐(1H)‐one scaffolds, which contain a functionalized tetrafluoroethyl group, have been prepared, characterized, and used in synthetic applications. Their corresponding electrophilic fluoroalkylation reactions with various sulfur, oxygen, phosphorus, and carbon‐centered nucleophiles afford products that feature a tetrafluoroethylene unit, which connects two functional moieties. A related λ3‐iodane that contains a fluorophore was shown to react with a cysteine derivative under mild conditions to give a thiol‐tagged product that is stable in the presence of excess thiol. Therefore, these new reagents show a significant potential for applications in chemical biology as tools for fast, irreversible, and selective thiol bioconjugation.
How do you write and present research well? Q4 – Do not metastasize with metadiscourse
Authors: Patience Gregory S. , Boffito Daria C. , Patience Paul A. 
Published: November 2015

AbstractIn the classic writing style, writers recognize that readers are competent and will recognize the truth as you lead them through your work. Soggy prose seeks “to argue for the truth.”[1] Your text should read like a conversation rather than a lecture. Match each sentence with one of the cardinal sins of writing to the left.[2,3] (Multiple choices possible)

1  Hedging
b)
In general these results show that a system with zero‐cost identities does not require centralized allocation of identities to encourage cooperation.[4]

2  Signposting
f)
In this section we shall evaluate the rate of recombination for nonequilibrium conditions.[5]

3  Redundant
c)
Here we report our new results on the samarium‐arsenide.[6]

4  Self‐conscious, 6 Boosting
e)
Whether established pests are suitable for attempted eradication is extremely controversial.[7]

5  Narcissism
d)
More recently researchers have attempted to quantify the effects of anxiety on foreign language learning.[8]

6  Boosting
a)
These results are extremely significant statistically and compare favorably with validation studies.[9]
Plasmon‐Induced Water Splitting Using Metallic‐Nanoparticle‐Loaded Photocatalysts and Photoelectrodes
Authors: Ueno Kosei , Oshikiri Tomoya , Misawa Hiroaki 
Published: November 2015

AbstractVisible‐ and near‐infrared‐light‐driven water splitting, which splits water molecules to generate hydrogen and oxygen gases, is a significant subject in artificial photosynthesis with the goal of achieving a low‐carbon society. In recent years, considerable attention has been paid to studies on the development of a plasmon‐induced water‐splitting system responding to visible light. In this review, we categorized water‐splitting systems as gold‐nanoparticle‐loaded semiconductor photocatalytic particles system and metallic‐nanoparticles‐loaded semiconductor photoelectrode systems, and introduce the latest studies according to these categories. Especially, we describe the studies that optimize a material or a structural design of metallic‐nanoparticle‐loaded semiconductor photoelectrodes and consider a whole water‐splitting system, including a cathode design. Furthermore, we discuss important points when studying plasmon‐induced water splitting, and we describe a methodology that enhances plasmon‐induced water‐splitting efficiency.
A high‐voltage stimulation chip for wearable stroke rehabilitation systems
Authors: Zeng Lei , Yi Xin , Shi Guoyong , Sawan Mohamad , Wang Guoxing 
Published: November 2015

SummaryIn this work, an 8‐channel high‐voltage (HV) stimulation chip for the rehabilitation of stroke patients through surface stimulation is presented. The chip receives control data through its serial peripheral interface and can be controlled by an external microcontroller. It can accordingly generate biphasic stimulation currents with different amplitudes, duration time, frequencies, and polarities for each channel independently. The chip was designed and fabricated using X‐FAB 0.35 µm HV mixed‐signal process. Circuits were carefully designed to ensure their operations under HVs. Our measurement results showed that a supply voltage of as high as 75 V can be achieved, and the current driver can generate biphasic stimuli with current amplitudes up to 4 mA. Copyright © 2015 John Wiley & Sons, Ltd.
Cytomorphology is often insufficient to categorize non‐small‐cell lung carcinoma on FNA specimens
Authors: Witt Benjamin L. , Cohen Michael B. , Chadwick Barbara E. , Stephenson Philip D. , Abasolo Peter , Schmidt Robert L. 
Published: November 2015

ObjectivesTo determine the accuracy and reproducibility of differentiating between squamous cell carcinoma (SCC) and adenocarcinoma (ADC) on fine‐needle aspiration (FNA) specimens.MethodsFifty cases of NSCLC diagnosed by FNA having either concurrent core biopsies or resection as a diagnostic reference standard were selected. FNA slides were reviewed independently by five blinded observers. Two rounds of review were performed. Cases were initially categorized as SCC, favor SCC, NSCLC (type indeterminate), favor ADC, or ADC; while the indeterminate category was eliminated in the second round of review.ResultsThe interobserver agreement was 0.22 and 0.1 with and without the indeterminate category, respectively. The overall accuracy for differentiating between SCC and ADC of the lung was 65% with the indeterminate category and 66% without.ConclusionOverall, the low interobserver agreement in our study indicates that accurate subclassification between the NSCLCs often cannot be made by cytomorphology alone. Diagn. Cytopathol. 2016;44:73–79. © 2015 Wiley Periodicals, Inc.
Weight bias internalization, emotion dysregulation, and non‐normative eating behaviors in prebariatric patients
Authors: Baldofski Sabrina , Rudolph Almut , Tigges Wolfgang , Herbig Beate , Jurowich Christian , Kaiser Stefan , Dietrich Arne , Hilbert Anja 
Published: November 2015

ABSTRACTObjectiveWeight bias internalization (WBI) is associated with eating disorder psychopathology and non‐normative eating behaviors among individuals with overweight and obesity, but has rarely been investigated in prebariatric patients. Based on findings demonstrating a relationship between emotion dysregulation and eating behavior, this study sought to investigate the association between WBI and eating disorder psychopathology as well as non‐normative eating behaviors (i.e., food addiction, emotional eating, and eating in the absence of hunger), mediated by emotion dysregulation.MethodWithin a consecutive multicenter study, 240 prebariatric patients were assessed using self‐report questionnaires. The mediating role of emotion dysregulation was examined using structural equation modeling.ResultsThe analyses yielded no mediational effect of emotion dysregulation on the association between WBI and eating disorder psychopathology. However, emotion dysregulation fully mediated the associations between WBI and emotional eating as well as eating in the absence of hunger. Further, emotion dysregulation partially mediated the relationship between WBI and food addiction symptoms.DiscussionPrebariatric patients with high levels of WBI are at risk for non‐normative eating behaviors, especially if they experience emotion regulation difficulties. These findings highlight the importance of interventions targeting WBI and improving emotion regulation skills for the normalization of eating behavior in prebariatric patients. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:180–185).
Aripiprazole, a partial dopamine agonist to improve adolescent anorexia nervosa—A case series
Authors: Frank Guido K.W. 
Published: November 2015

ABSTRACTAnorexia nervosa (AN) is a severe and complex psychiatric disorder and no medication has been approved for its treatment. This case series in youth with severe, recurrent AN supports the hypothesis that dopamine receptor agonists could be helpful in supporting fear extinction during eating disorder focused psychotherapy and therefore support recovery from AN. © 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2016; 49:529–533).
Comparison of systemic therapies used concurrently with radiation for the treatment of human papillomavirus–associated oropharyngeal cancer
Authors: Nien Hsin‐Hua , Sturgis Erich M. , Kies Merrill S. , El‐Naggar Adel K. , Morrison William H. , Beadle Beth M. , Johnson Faye M. , Gunn Gary B. , Fuller Clifton D. , Phan Jack , Gold Kathryn A. , Frank Steven J. , Skinner Heath , Rosenthal David I. , Garden Adam S. 
Published: November 2015

AbstractBackgroundThis was a retrospective study of patients with human papillomavirus (HPV)‐associated oropharyngeal cancer treated with concurrent systemic therapy and radiation.MethodsData were extracted through chart review, and statistical analyses included frequency tabulation, chi‐square, and Kaplan–Meier tests.ResultsThree hundred thirty‐nine patients were analyzed; 166 received neoadjuvant chemotherapy. One hundred thirty‐six patients were treated with cisplatin, 123 with cetuximab, and 59 with carboplatin. The 2‐, 3‐, and 5‐year actuarial overall survival rates were 92%, 88%, and 78%, respectively. There were no significant differences in survival or disease control when analyzed by systemic agent. Platin‐treated patients had greater hematologic toxicity, and required more intravenous hydration. The incidence of confluent mucositis was highest among patients treated with cetuximab.ConclusionPlatin and cetuximab seem to have similar efficacy when delivered concurrently with radiation in our retrospective population study. Although platin did cause greater hematologic toxicity, radiation‐specific side effects seemed relatively comparable. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1554–E1561, 2016
Channels of Risk Sharing at Micro Level: Savings, Investments and Risk Aversion Heterogeneity
Authors: Balli Faruk , Pericoli Filippo Maria , Pierucci Eleonora 
Published: November 2015

AbstractApplying the standard income variance decomposition methodology, the paper explores for the first time the role and the extent of smoothing channels at a micro level using a sample of UK households. Our empirical analysis of British Household Panel Survey data concludes that the bulk of risk sharing in the UK is driven by the savings channel. By allowing for risk aversion heterogeneity, we detect an inverted U‐shaped relationship between risk aversion and the extent of smoothing achieved through financial markets. We also analyse the issue of risk sharing by income, education levels and region. We find that risk sharing is more effective (higher) for individuals whose savings are more flexible, while it is less effective (lower) for individuals characterized by more stable savings rate (like the Scottish population), regardless of their economic conditions. Copyright © 2015 John Wiley & Sons, Ltd.
Systematic implications of brain morphology in potamotrygonidae (Chondrichthyes: Myliobatiformes)
Authors: Fontenelle João Pedro , de Carvalho Marcelo R. 
Published: November 2015

ABSTRACTThe gross brain morphology, brain proportions, and position of cranial nerves in all four genera (Potamotrygon, Plesiotrygon, Paratrygon, and Heliotrygon) and 11 of the species of the Neotropical stingray family Potamotrygonidae were studied to provide new characters that may have a bearing on internal potamotrygonid systematics. The brain was also studied in four other stingray (Myliobatiformes) genera (Hexatrygon, Taeniura, Dasyatis, and Gymnura) to provide a more inclusive phylogenetic context for the interpretation of features of the brain in potamotrygonids. Our results indicate, based on neuroanatomical characters, that the genera Paratrygon and Heliotrygon are sister groups, as are the genera Potamotrygon and Plesiotrygon, agreeing with previous morphological and molecular phylogenetic studies. Both groups of genera share distinct conditions of the olfactory tracts, telencephalon and its central nuclei, hypophysis and infundibulum, morphology and orientation of the metencephalic corpus cerebelli, orientation of the glossopharyngeal nerve, and overall encephalic proportions. The corpus cerebelli of Paratrygon and Heliotrygon is interpreted as being more similar to the general batoid condition and, given their phylogenetic position highly nested within stingrays, is considered secondarily derived, not plesiomorphically retained. Our observations of the corpus cerebelli of stingrays, including Hexatrygon, corroborate that the general stingray pattern previously advanced by Northcutt is derived among batoids. The morphology of the brain is shown to be a useful source of phylogenetically informative characters at lower hierarchical levels, such as between genera and species, and thus, has significant potential in phylogenetic studies of elasmobranchs. J. Morphol. 277:252–263, 2016. © 2015 Wiley Periodicals, Inc.
Longitudinal cerebellar growth following very preterm birth
Authors: Lee Wayne , Al‐Dossary Hisham , Raybaud Charles , Young Julia M. , Morgan Benjamin R. , Whyte Hilary E.A. , Sled John G. , Taylor Margot J. , Shroff Manohar M. 
Published: November 2015

PurposeTo measure cerebellar growth in a longitudinal cohort of very preterm infants to identify early predictors of subsequent brain growth. Although the cerebellum grows rapidly during late gestation, the rate and variability of growth following premature birth, and the effects of associated injury, are largely unknown.Materials and MethodsIn all, 105 very‐preterm born infants (24–32 weeks GA) were imaged using magnetic resonance imaging (MRI) at birth, term‐equivalent, 2, and 4 years of age. Cerebellar and total cerebral volumes were estimated from 1 mm isotropic T1‐weighted scans acquired at 1.5T and 3T, using an atlas‐based approach. Linear models were used to analyze cerebellar volume as cross‐sectional and longitudinal functions of age, clinical, and radiological correlates. Linear models were also used to test for associations between volume and cognitive outcome.ResultsCerebellar volume increased rapidly with age‐at‐scan during both the preterm (0.7 mL/wk, P < 0.001) and term periods (1.8 mL/wk, P < 0.001). Infants with grade 3 or 4 germinal matrix hemorrhage (GMH) had smaller cerebellar volumes as a percentage of total brain volume starting at birth and continuing to 4 years of age (–0.43%, –0.57%, –1.09% at preterm, term, and 4 years, respectively, P < 0.01). Irrespective of age‐at‐scan, early cerebellar volume was predictive of volume at 4 years of age (slope = 1.3, P < 0.001). Cerebellar volumes were not found to predict cognitive outcome at 4 years of age; P < 0.2.ConclusionHigh‐grade GMH and small perinatal cerebellar size is predictive of cerebellar development up to 4 years of age. These findings suggest that it is possible to identify individuals at high risk of reduced cerebellar volumes at an early age. J. Magn. Reson. Imaging 2016;43:1462–1473.