bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indonesian public healthcare service institution’s patient satisfaction barometer (IPHSI-PSB)
Authors: Sumaedi Sik , Yuda Bakti I Gede Mahatma , Rakhmawati Tri , Astrini Nidya J. , Widianti Tri , Yarmen Medi 
Published: December 2015

Purpose– The purpose of this paper is to develop and test a new public healthcare patient satisfaction index (PSI) in Indonesia. More clearly, the index measures overall patient satisfaction and its determinants.Design/methodology/approach– Literature review was performed to identify the determinants of patient satisfaction. Data collection was carried out by using survey with questionnaire. The survey involves 161 patients of one public healthcare service institution in Tangerang, Indonesia. The authors conducted some statistical analyses, namely exploratory factor analysis, Cronbachαanalysis, and multiple regression analysis.Findings– A new public healthcare PSI was developed and tested. The index consists of overall patient satisfaction and its determinants. The determinants include the quality of healthcare delivery, the quality of healthcare personnel, the adequacy of healthcare resources, the quality of administration process, perceived value, perceived sacrifice, and image. Furthermore, the new index was called as IPHSI-PSB.Research limitations/implications– This research was carried out only in Tangerang, Indonesia and only involved one public healthcare service. Hence, the index needs to be tested in different cities in Indonesia. Furthermore, it is also needed to involve more public healthcare service institutions in future researches.Practical implications– Public healthcare service managers can use IPHSI-PSB to monitor, measure, and improve the patient satisfaction of the public healthcare service institution they manage.Originality/value– This paper has developed and tested a new public healthcare patient satisfaction index.
Exploring the effects of physical punishment on aggressive behavior and peer victimization: a conditional process analysis
Authors: Söderberg Patrik , Bjorkqvist Kaj , Österman Karin 
Published: December 2015

Purpose
– Recent studies indicate that exposure to physical punishment is associated with both aggressive behavior and peer victimization at school. The purpose of this paper is to explore the bidirectional relationship between aggressive behavior and peer victimization as outcomes of physical punishment, as well as the role of depressive symptoms.

Design/methodology/approach
– A sample of 2,424 Finnish upper primary school pupils (1,282 girls, 1,148 boys, mean age=14.2, SD=1.0) completed an online survey during class. Two conditional process models were applied using a macro for SPSS developed by Hayes (2012).

Findings
– Exposure to physical punishment was found to be associated with both aggressive behavior and peer victimization at school. The effect on victimization was partially mediated by aggressive behavior and depressive symptoms, whereas the effect on aggressive behavior was partially mediated by peer victimization experiences but not by depressive symptoms. The relationship between physical punishment and peer victimization was somewhat stronger for girls than for boys, but this effect was not accounted for by gender differences in depressive symptoms or aggressive behavior.

Originality/value
– Few studies to date have addressed the connection between aggressive behavior and peer victimization as outcomes of physical punishment. In addition, the study expands on the concept of “victim personality” by examining the mediating role of depressive symptoms. Methodologically, the study is an example of how the statistical software SPSS can be used for multiple mediation and conditional process analysis as an alternative to SEM analyses.
Police and crime commissioners: emerging “drug policy actors”?
Authors: Austen Liz 
Published: December 2015

Purpose
– In 2013, the Police and Crime Commissioner (PCC) for Durham, Ron Hogg, initiated a debate around the future of British drug policy. In June 2015, the Derbyshire PCC, Alan Charles, opened a similar debate with representatives from policing, third party support agencies, national advocates and academics to discuss the possibilities for change. This short paper presents the views and actions of senior figures in the police service and discusses motivations for pursuing change. The purpose of this paper is to introduce police and crime commissioners as “drug policy actors” (Seddon, 2011) and to highlight key areas for further academic enquiry.

Design/methodology/approach
– This paper is based on press releases and media accounts of the recent activity of the PCCs in relation to national drug policy. This paper provides an academic viewpoint on recent events, supported by theoretical literature critiquing drug policy and contemporary policing.

Findings
– This viewpoint articulates that motivations for pursuing a change in drug policy are based on both economic and ideological agendas of some PCCs. Irrespective of the motivation, pressure from PCCs and renowned Chief Constables may be more effective in initiating change than high-profile national campaigns and political debates.

Originality/value
– This paper is the first of its kind to discuss the relationship between PCCs/local constabularies and drug policy reform. It provides a foundation for future research which could investigate views on alternatives to prohibition, specifically within the wider police force.
Youth in the UK: 99 problems but the gang ain
'
t one?
Authors: Smithson Hannah , Ralphs Rob 
Published: December 2015

Purpose
– At a time when youth gangs and gang policy feature significantly in the discourse on UK youth, it is judicious to critique the framework and evidence upon which these policy developments have originated. The political focus on gangs was heightened, in part, by the English riots in 2011. The reaction to the riots was a “concerted all-out war on gangs” and led to the development of the national Ending Gangs and Youth Violence (EGYV) strategy. The paper aims to discuss these issues.

Design/methodology/approach
– The authors use Manchester as a case study to illustrate what the they argue to be the misplaced focus of the current EGYV strategy and provide a detailed critique of the strategy to date.

Findings
– The paper suggests that government funded gang interventions are currently bereft of a “what works” approach and should only be implemented when the authors have significantly developed the knowledge and understanding of gangs in a local context.

Originality/value
– The paper calls for a stronger evidence based policy approach to tackling gangs.
Realising the vision of communication inclusion
Authors: Hartley Kean Kim 
Published: December 2015

Purpose
– The purpose of this paper is to provide a commentary on Clare Mander’s paper entitled “An investigation of the delivery of health-related accessible information for adults with learning disabilities”. The commentary discusses issues identified by the author in the field of accessible information and, more generally, inclusive communication practice.

Design/methodology/approach
– This commentary reviews factors which influence the communication accessibility of services and the policy, legislative and economic case for mainstreaming inclusive communication approaches. It highlights diversity in the definition of inclusive communication and the scope of its necessary implementation before proposing an approach to establishing consensus on the way forward. The commentary suggests how the task of mainstreaming inclusive communication throughout public services could be addressed, reflects on progress to date and proposes next steps for the growing numbers of those with an interest.

Findings
– Many factors influence communication accessibility. The communication attitude, knowledge, skills and resources individual providers and recipients bring to each interaction are as important as the whole organisation’s approach towards and investment in inclusive communication approaches. Legislation, policy, demographics and reducing budgets increase the requirement to mainstream inclusive communication approaches. Achieving this objective is an enormous task.

Originality/value
– Reflecting on all the drivers and influences on the objective of achieving mainstreamed quality inclusive communication practice throughout public services, the author offers potential suggestions for starting to address this enormous but worthwhile task with a view to generating discussion and collaboration among those with an interest.
Assessment of the contribution of chemoreceptor‐based signalling to biofilm formation
Authors: Corral‐Lugo Andrés , De la Torre Jesús , Matilla Miguel A. , Fernández Matilde , Morel Bertrand , Espinosa‐Urgel Manuel , Krell Tino 
Published: December 2015

SummaryAlthough it is well established that one‐ and two‐component regulatory systems participate in regulating biofilm formation, there also exists evidence suggesting that chemosensory pathways are also involved. However, little information exists about which chemoreceptors and signals modulate this process. Here we report the generation of the complete set of chemoreceptor mutants of Pseudomonas putida KT2440 and the identification of four mutants with significantly altered biofilm phenotypes. These receptors are a WspA homologue of Pseudomonas aeruginosa, previously identified to control biofilm formation by regulating c‐di‐GMP levels, and three uncharacterized chemoreceptors. One of these receptors, named McpU, was found to mediate chemotaxis towards different polyamines. The functional annotation of McpU was initiated by high‐throughput thermal shift assays of the receptor ligand binding domain (LBD). Isothermal titration calorimetry showed that McpU‐LBD specifically binds putrescine, cadaverine and spermidine, indicating that McpU represents a novel chemoreceptor type. Another uncharacterized receptor, named McpA, specifically binds 12 different proteinogenic amino acids and mediates chemotaxis towards these compounds. We also show that mutants in McpU and WspA‐Pp have a significantly reduced ability to colonize plant roots. Data agree with other reports showing that polyamines are signal molecules involved in the regulation of bacteria–plant communication and biofilm formation.
Healthcare quality and safety: a review of policy, practice and research
Authors: Waring Justin , Allen Davina , Braithwaite Jeffrey , Sandall Jane 
Published: December 2015

AbstractOver the last two decades healthcare quality and safety have risen to the fore of health policy and research. This has largely been informed by theoretical and empirical ideas found in the fields of ergonomics and human factors. These have enabled significant advances in our understanding and management of quality and safety. However, a parallel and at time neglected sociological literature on clinical quality and safety is presented as offering additional, complementary, and at times critical insights on the problems of quality and safety. This review explores the development and contributions of both the mainstream and more sociological approaches to safety. It shows that where mainstream approaches often focus on the influence of human and local environment factors in shaping quality, a sociological perspective can deepen knowledge of the wider social, cultural and political factors that contextualise the clinical micro‐system. It suggests these different perspectives can easily complement one another, offering a more developed and layered understanding of quality and safety. It also suggests that the sociological literature can bring to light important questions about the limits of the more mainstream approaches and ask critical questions about the role of social inequality, power and control in the framing of quality and safety.
The Limits of Shrinkage: Conceptual Pitfalls and Alternatives in the Discussion of Urban Population Loss
Authors: Bernt Matthias 
Published: December 2015

AbstractThis essay reflects on the conceptual underpinnings of research on ‘shrinking cities' over the last decade. It criticizes the definition of shrinkage in terms of urban population losses and argues that the state‐of‐the art research on ‘shrinking cities' suffers from a misleading conceptualization of shrinkage which forces essentially different urban constellations into a universal model of ‘shrinkage'. Four problems of this procrustean bed are discussed in detail: methodological pitfalls of threshold definitions of urban shrinkage; empirical contradictions; an absence of attention to scalar interrelations; and insufficient understanding of cities as historical processes. The essay ends with suggestions for a widened conceptualization of shrinkage and a new research agenda.
Evaluation of bias on the assessment of diet breadth of herbivorous insects using molecular methods
Authors: De la Cadena Gissela , Papadopoulou Anna , Maes Jean‐Michel , Gómez‐Zurita Jesús 
Published: December 2015

AbstractThe interactions between herbivores and their host plants play a key role in ecological processes. Understanding the width and nature of these interactions is fundamental to ecology and conservation. Recent research on DNA‐based inference of trophic associations suggests that the host range of phytophagous insects in the tropics may be wider than previously thought based on traditional observation. However, the reliability of molecular inference of ecological associations, still strongly dependent on PCR and thus exposed to the risk of contamination with environmental DNA, is under debate. Here, we explored alternative procedures to reduce the chance of amplification of external, nondiet DNA, including surface decontamination and analysis of mid/hind guts, comparing the results with those obtained using the standard protocol. We studied 261 specimens in eight species of Neotropical Chrysomelidae that yielded 316 psbA‐trnH intergenic spacer sequences (cpDNA marker of putative diets) from unique and multiple‐band PCR results. The taxonomic identity of these sequences was inferred using the automated pipeline BAGpipe, yielding results consistent with 31 plant families. Regardless of the protocol used, a wide taxonomic spectrum of food was inferred for all chrysomelid species. Canonical Correspondence Analysis using these data revealed significant differences attributed mainly to species (expectedly, since they represent different ecologies), but also to treatment (untreated vs. cleaned/gut samples) and PCR results (single vs. multiple bands). Molecular identification of diets is not straightforward and, regardless of the species’ niche breadth, combining approaches that reduce external contamination and studying multiple individuals per species may help increasing confidence in results.
Modeling of the Temperature Effect on Oxygen Absorption by Iron‐Based Oxygen Scavengers
Authors: Polyakov Vladimir A. , Miltz Joseph 
Published: December 2015

AbstractA new engineering‐oriented model for prediction of the effect of temperature on the kinetics of oxygen absorption by iron‐based oxygen scavengers (IOSs) was developed. The model is based on the physicochemical mechanism of the O2 scavenging process by the active component of the IOS (iron powder). The conclusions of this study are: (1) the iron deposits formed on the iron particles are composed of 2 different layers: an inner layer of Fe3O4 and an outer layer of FeOOH that vanishes with the depletion of oxygen. (2) The model considers the chemical processes in the heterogeneous closed system “Fe–H2O–NaCl–O2” and describes the kinetics of oxygen absorption by the powder, depending on the characteristics of the system. (3) The nonlinear ordinary differential equation (ODE) of the O2 absorption kinetics was derived and a simple approximate solution to this ODE was obtained theoretically that is similar to the empirical exponential formula published in the relevant literature. (4) The temperature dependence of the oxygen absorption rate is more complicated than that described by the Arrhenius equation.
Thyroid Doppler US: Tips and tricks
Authors: Lacout Alexis , Chevenet Carole , Salas Joël , Marcy Pierre Yves 
Published: December 2015

SummaryIncidental diagnosis of thyroid nodules is very common on adult neck ultrasonography (US) examination. They are primarily assessed on size and greyscale ultrasound criteria such as hypoechogenicity, taller than wide, spiculated margins and calcifications. In difficult situations Doppler US features may improve tumour characterisation and staging.
Agranulocytosis and mixed‐type autoimmune hemolytic anemia in primary sjögren's syndrome: a case report and review of the literature
Authors: Qiao Lin , Chen Jing , Leng Xiao‐mei , Zhang Wen , Han Bing , Zhao Yan , Zeng Xiao‐feng 
Published: December 2015

AbstractPrimary Sjögren's syndrome (pSS) is a systemic autoimmune disease that presents with sicca symptoms of the main mucosal surfaces. Patients with pSS have a broad spectrum of laboratory features, such as cytopenias and hypergammaglobulinemia. Although hematological abnormalities are usually seen in pSS patients, agranulocytosis and autoimmune hemolytic anemia (AIHA) are rare. Here we describe a 40‐year‐old woman with pSS who developed both agranulocytosis and mixed‐type AIHA. An increased risk of malignancies has also been reported in pSS patients with hematological changes. Although there is no evidence of malignancies, this patient should be closely followed up in case of developing lymphoma.
Oxygen saturation profile of term equivalent extreme preterm infants at discharge – comparison with healthy term counterparts
Authors: Rath Chandra , Kluckow Martin 
Published: December 2015

AbstractAimCompare the oxygen saturation profiles before discharge of neonates born extremely preterm (<28 weeks), now at term equivalent age, with healthy term neonates and assess the impact of feeding on this profile in each group.MethodsWe prospectively evaluated and compared the oxygen saturation profile in 15 very low birthweight infants at term equivalent age, ready to be discharged home without any oxygen and 15 term newborns after 48 hours of life. We also evaluated and compared the saturations of these two groups during a one‐hour period during and after feeding.ResultsTerm equivalent preterm and term infants spent median 3% and 0%, respectively, of the time below 90% in a 12‐hour saturation‐recording period. Term infants spent a median 0.26% and 0.65% of the time in <90% saturation during feed time and no feed time, respectively. In contrast, preterm infants spent significantly more time <90% saturation (3.47% and 3.5% during feed time and no feed time, respectively).ConclusionTerm equivalent preterm infants spent significantly more time in a saturation range <90% compared to term infants. Feeding had little effect on saturation profile overall within each group.
Choosing a Model of Maternity Care: Decision Support Needs of Australian Women
Authors: Stevens Gabrielle , Miller Yvette D. , Watson Bernadette , Thompson Rachel 
Published: December 2015

AbstractBackgroundAccess to information on the features and outcomes associated with the various models of maternity care available in Australia is vital for women's informed decision‐making. This study sought to identify women's preferences for information access and decision‐making involvement, as well as their priority information needs, for model of care decision‐making.MethodsA convenience sample of adult women of childbearing age in Queensland, Australia were recruited to complete an online survey assessing their model of care decision support needs. Knowledge on models of care and socio‐demographic characteristics were also assessed.ResultsAltogether, 641 women provided usable survey data. Of these women, 26.7 percent had heard of all available models of care before starting the survey. Most women wanted access to information on models of care (90.4%) and an active role in decision‐making (99.0%). Nine priority information needs were identified: cost, access to choice of mode of birth and care provider, after hours provider contact, continuity of carer in labor/birth, mobility during labor, discussion of the pros/cons of medical procedures, rates of skin‐to‐skin contact after birth, and availability at a preferred birth location. This information encompassed the priority needs of women across age, birth history, and insurance status subgroups.ConclusionsThis study demonstrates Australian women's unmet needs for information that supports them to effectively compare available options for model of maternity care. Findings provide clear direction on what information should be prioritized and ideal channels for information access to support quality decision‐making in practice.
Decursin enhances TRAIL‐induced apoptosis through oxidative stress mediated‐ endoplasmic reticulum stress signalling in non‐small cell lung cancers
Authors: Kim Jaekwang , Yun Miyong , Kim Eun‐Ok , Jung Deok‐Beom , Won Gunho , Kim Bonglee , Jung Ji Hoon , Kim Sung‐Hoon 
Published: December 2015

Background and PurposeThe TNF‐related apoptosis‐inducing ligand (TRAIL) is a promising anticancer agent due to its remarkable ability to selectively kill tumour cells. However, because most tumours exhibit resistance to TRAIL‐induced apoptosis, the development of combination therapies to overcome resistance to TRAIL is required for effective cancer therapy.Experimental ApproachCell viability and possible synergy between the plant pyranocoumarin decursin and TRAIL was measured by MTT assay and calcusyn software. Reactive oxygen species (ROS) and apoptosis were measured using dichlorodihydrofluorescein and annexin/propidium iodide in cell flow cytometry. Changes in protein levels were assessed with Western blotting.Key ResultsCombining decursin and TRAIL markedly decreased cell viability and increased apoptosis in TRAIL‐resistant non‐small‐cell lung cancer (NSCLC) cell lines. Decursin induced expression of the death receptor 5 (DR5). Inhibition of DR5 attenuated apoptotic cell death in decursin + TRAIL treated NSCLC cell lines. Interestingly, induction of DR5 and CCAAT/enhancer‐binding protein homologues protein by decursin was mediated through selective induction of the pancreatic endoplasmic reticulum kinase (PERK)/activating transcription factor 4 (ATF4) branch of the endoplasmic reticulum stress response pathway. Furthermore, enhancement of PERK/ATF4 signalling by decursin was mediated by ROS generation in NSCLC cell lines, but not in normal human lung cells. Decursin also markedly down‐regulated expression of survivin and Bcl‐xL in TRAIL‐resistant NSCLC cells.Conclusions and ImplicationsROS generation by decursin selectively activated the PERK/ATF4 axis of the endoplasmic reticulum stress signalling pathway, leading to enhanced TRAIL sensitivity in TRAIL‐resistant NSCLC cell lines, partly via up‐regulation of DR5.
Genotyping HLA‐B*5801 for Allopurinol‐Induced Severe Cutaneous Adverse Reactions: An Accurate and Prompt Method
Authors: Cheng Lin , Zhang Lihua , Gao Lichen , Zhang Wei , Chen Xiaoping , Zhou Hong‐Hao 
Published: December 2015

AbstractObjectivesA new method of HLA‐B*5801 genotyping was compared with sequence‐based typing (SBT) to find an accurate and prompt method in genotyping HLA‐B*5801.MethodsTwo groups of patients from allopurinol‐induced cutaneous adverse reactions (SCARs) and allopurinol‐tolerant were both genotyped with PG5801 kit and SBT method. The genotyping results of HLA‐B*5801 were compared between the two groups.ResultsThe PG5801 detection kit results were 100% (79/79) in agreement with the SBT genotyping results for identifying the HLA‐B*5801 (+) patients. No false‐positive or false‐negative errors were found. The sensitivity, specificity, rate of adherence, positive predictive value (PPV) and negative predictive value (NPV) were 100%.ConclusionThe potential fast screening method is an ideal tool to rule out the high‐risk allopurinol‐induced SCARs patients.