bluuebunny/crossref_metadata_2025_split huggingface dataset:
Guaranteed estimation of solutions to Helmholtz transmission problems with uncertain data from their indirect noisy observations
Authors: Podlipenko Yu. K. , Shestopalov Yu. V. 
Published: August 2017

AbstractWe investigate the guaranteed estimation problem of linear functionals from solutions to transmission problems for the Helmholtz equation with inexact data. The right‐hand sides of equations entering the statements of transmission problems and the statistical characteristics of observation errors are supposed to be unknown and belonging to certain sets. It is shown that the optimal linear mean square estimates of the above mentioned functionals and estimation errors are expressed via solutions to the systems of transmission problems of the special type. The results and techniques can be applied in the analysis and estimation of solution to forward and inverse electromagnetic and acoustic problems with uncertain data that arise in mathematical models of the wave diffraction on transparent bodies.
Assessment of Novel Long‐Lasting Ceria‐Stabilized Zirconia‐Based Ceramics with Different Surface Topographies as Implant Materials
Authors: Altmann Brigitte , Karygianni Lamprini , Al‐Ahmad Ali , Butz Frank , Bächle Maria , Adolfsson Erik , Fürderer Tobias , Courtois Nicolas , Palmero Paola , Follo Marie , Chevalier Jérôme , Steinberg Thorsten , Kohal Ralf Joachim 
Published: August 2017

AbstractThe development of long‐lasting zirconia‐based ceramics for implants, which are not prone to hydrothermal aging, is not satisfactorily solved. Therefore, this study is conceived as an overall evaluation screening of novel ceria‐stabilized zirconia–alumina–aluminate composite ceramics (ZA8Sr8‐Ce11) with different surface topographies for use in clinical applications. Ceria‐stabilized zirconia is chosen as the matrix for the composite material, due to its lower susceptibility to aging than yttria‐stabilized zirconia (3Y‐TZP). This assessment is carried out on three preclinical investigation levels, indicating an overall biocompatibility of ceria‐stabilized zirconia‐based ceramics, both in vitro and in vivo. Long‐term attachment and mineralized extracellular matrix (ECM) deposition of primary osteoblasts are the most distinct on porous ZA8Sr8‐Ce11p surfaces, while ECM attachment on 3Y‐TZP and ZA8Sr8‐Ce11 with compact surface texture is poor. In this regard, the animal study confirms the porous ZA8Sr8‐Ce11p to be the most favorable material, showing the highest bone‐to‐implant contact values and implant stability post implantation in comparison with control groups. Moreover, the microbiological evaluation reveals no favoritism of biofilm formation on the porous ZA8Sr8‐Ce11p when compared to a smooth control surface. Hence, together with the in vitro in vivo assessment analogy, the promising clinical potential of this novel ZA8Sr8‐Ce11 as an implant material is demonstrated.
Liposome‐Indocyanine Green Nanoprobes for Optical Labeling and Tracking of Human Mesenchymal Stem Cells Post‐Transplantation In Vivo
Authors: Mazza Mariarosa , Lozano Neus , Vieira Debora Braga , Buggio Maurizio , Kielty Cay , Kostarelos Kostas 
Published: August 2017

AbstractDirect labeling of human mesenchymal stem cells (hMSC) prior to transplantation provides a means to track cells after administration and it is a powerful tool for the assessment of new cell‐based therapies. Biocompatible nanoprobes consisting of liposome‐indocyanine green hybrid vesicles (liposome‐ICG) are used to safely label hMSC. Labeled hMSC recapitulating a 3D cellular environment is transplanted as spheroids subcutaneously and intracranially in athymic nude mice. Cells emit a strong NIR signal used for tracking post‐transplantation with the IVIS imaging system up to 2 weeks (subcutaneous) and 1 week (intracranial). The transplanted stem cells are imaged in situ after engraftment deep in the brain up to 1 week in living animals using optical imaging techniques and without the need to genetically modify the cells. This method is proposed for efficient, nontoxic direct cell labeling for the preclinical assessment of cell‐based therapies and the design of clinical trials, and potentially for localization of the cell engraftment after transplantation into patients.
Metal‐Free Aerobic Oxidative C−C Bond Cleavage between the Carbonyl Carbon and the α‐Carbon of α‐Azido Ketones: A Novel Synthesis of N‐Alkylated Benzamides
Authors: Reddy Chada Narsimha , Krishna Namballa Hari , Reddy V. Ganga , Alarifi Abdullah , Kamal Ahmed 
Published: August 2017

AbstractAn unprecedented metal‐free approach has been achieved for the synthesis of N‐alkylated benzamides from phenacyl azides by oxidative cleavage of a C−C bond and formation of a new C−N bond in the presence of K2CO3. Various substituted phenacyl azides could be readily cleaved to access a variety of N‐alkylated benzamides by using the new protocol, which is a viable alternative for the construction of amide bonds. This metal‐free reaction forms amides in excellent yields with minimal generation of waste. The high functional group tolerance and diverse substrate scope make this reaction useful for organic synthesis.
Exploring the effectiveness of continuous activity with automatic feedback in online calculus
Authors: Sancho‐Vinuesa Teresa , Masià Ramon , Fuertes‐Alpiste Marc , Molas‐Castells Núria 
Published: August 2017

AbstractAcademic results in mathematics subjects in engineering, especially those taught online, are poor. The key contextual elements of an insufficient level of prior knowledge, poor motivation, and the intrinsic difficulty of the subject matter has led to the review of the study materials and the creation of a methodology based on continuous assessment with automatic feedback at the Universitat Oberta de Catalunya. The main objective of this article is to present evidence of improved learning outcomes with the application and use of WIRIS quizzes as an automatic assessment tool in calculus subjects. To that end, we carried out descriptive research with an ex‐post‐facto design, based on statistical analysis of the results for continuous assessment and students’ grades in 11 semesters. The new strategy has been applied in the last two academic years, based on introductory Moodle lessons and assessment with interactive questionnaires. The data obtained are inconclusive: In the first two semesters that the methodology was implemented, the results show a noticeable improvement in several key aspects, such as undertaking and passing the continuous assessment and improved results across the spectrum of grades. However, in the last two semesters, the results are generally similar to those obtained with the old methodology.
Iron Oxide Nanoclusters Incorporated into Iron Phthalocyanine as Highly Active Electrocatalysts for the Oxygen Reduction Reaction
Authors: Cheng Yi , Liang Ji , Veder Jean‐Pierre , Li Meng , Chen Shuangming , Pan Jian , Song Li , Cheng Hui‐Ming , Liu Chang , Jiang San Ping 
Published: August 2017

AbstractIron‐nitrogen‐carbon (Fe‐N‐C) composites have emerged as active and non‐precious‐metal electrocatalysts for the oxygen reduction reaction (ORR). Here, we developed a simple process to synthesize FeOx nanoclusters (NCs) incorporated with iron phthalocyanine (FePc) supported on graphene (FeOx/FePc) as highly active electrocatalysts for the ORR by a self‐assembly method. The electrochemical activity of FeOx/FePc depends on the loading or size of the FeOx NCs. The best results are obtained on FeOx/FePc with 10 wt % FeOx NCs of a size of approximately 2 nm and a thickness of approximately 0.6 nm, which achieves a half‐wave potential of 0.888 V and current density of 37.6 Ag−1 at 0.9 V (vs. the reversible hydrogen electrode). This is 50 mV higher than that of FePc supported on graphene and 64 mV higher than that of Pt/C in 0.1 m KOH solution at a catalyst loading of 0.1 mg cm−2. X‐ray absorption spectroscopy and electrochemical cyclic voltammetry results indicate that the incorporated FeOx NCs interact with the active center of FePc, Fe−N4, to enhance the electron transition and reversibility of the FeIII/FeII redox couple and promote the kinetics of the ORR. We demonstrate that the nature of the active center of FePc (i.e., Fe−N4) is related closely to the activity of the FeIII/FeII redox couple.
A new model for the formation of microbial polygons in a coastal sabkha setting
Authors: Lokier Stephen W. , Andrade Luiza L. , Court Wesley M. , Dutton Kirsten E. , Head Ian M. , van der Land Cees , Paul Andreas , Sherry Angela 
Published: August 2017

AbstractThe stratigraphic record of microbially induced sedimentary structures spans most of the depositional record. Today, microbes continue to generate, bind and modify sediments in a vast range of depositional environments. One of the most cited of these settings is the coastal microbial mat system of the Persian/Arabian Gulf. In this setting, an extensive zone of microbial mat polygons has previously been interpreted as resulting from desiccation‐related contraction during episodic drying. This study employs 15 years of field‐based monitoring of the interaction between environmental factors and the development and evolution of polygon morphologies to test the desiccation model in this setting. On the basis of these observations, a new model is proposed that accounts for the genesis and development of microbial polygons without the need for desiccation‐induced shrinkage. Conversely, the formation, development and erosion of microbial polygons is a direct result of the production of large amounts of organic matter in a healthy, yet spatially limited, microbial community. The recognition of microbial polygons has previously been applied as a diagnostic tool for the reconstruction of ancient depositional environments. The present study calls these interpretations into doubt. It is inferred that preservation of the microbial polygons as a recognizable form would be rare. Biological degradation and compaction will reduce polygons to produce the ‘wispy’ laminae that are a common feature of ancient sabkha lithofacies.
Effect of Deficit Irrigation Regimes on Yield and Fruit Quality of Olive Trees (cv. Memecik) on the Aegean Coast of Turkey
Authors: Kaya Ü. , Öztürk Güngör F. , Çamoğlu G. , Akkuzu E. , Aşik Ş. , Köseoğlu O. 
Published: August 2017

AbstractIn this study, six different irrigation treatments were applied to an olive orchard using the drip irrigation method. Five of these were arranged according to 25% (S0.25), 50% (S0.50), 75% (S0.75), 100% (S1.00) and 125% (S1.25) of the evaporation in 5 days of a class ‘A’ evaporation pan, and one control (SC) was arranged so as to bring the reducing moisture at a soil depth of 0–90 cm to field capacity. Yield values were not affected by the irrigation treatment (p > 0.05). In contrast, 100‐fruit weight, pulp ratio, hardness moisture, oil, reducing sugar content and bitterness were affected by irrigation (p < 0.05). Generally, an increase in the amount of irrigation water given in the study was accompanied by a fall in ripeness index values, a rise in moisture content, and a reduction in the oil content of fruit. The highest content of reducing sugar was obtained from S0.25, generally being lower with increase in the water applied. The findings show that application of 25% of the evaporation of a class ‘A’ evaporation pan (treatment S0.25) can be recommended for cv. Memecik. Application of this recommendation can achieve a 72% saving in water and make a significant contribution to the conservation of limited water resources. Copyright © 2017 John Wiley & Sons, Ltd.
Bibliometric Analysis of Female Authorship Trends and Collaboration Dynamics Over JBMR's 30-Year History
Authors: Wininger Austin E , Fischer James P , Likine Elive F , Gudeman Andrew S , Brinker Alexander R , Ryu Jonathan , Maupin Kevin A , Lunsford Shatoria , Whipple Elizabeth C , Loder Randall T , Kacena Melissa A 
Published: August 2017

ABSTRACT

In academia, authorship is considered a currency and is important for career advancement. As the Journal of Bone and Mineral Research (JBMR) is the highest-ranked journal in the field of bone, muscle, and mineral metabolism and is the official publication of the American Society for Bone and Mineral Research, we sought to examine authorship changes over JBMR's 30-year history. Two bibliometric methods were used to collect the data. The “decade method” included all published manuscripts throughout 1 year in each decade over the past 30 years starting with the inaugural year, yielding 746 manuscripts for analysis. The “random method” examined 10% of published manuscripts from each of the 30 years, yielding 652 manuscripts for analysis. Using both methods, the average number of authors per manuscript, numerical location of the corresponding author, number of collaborating institutions, number of collaborating countries, number of printed manuscript pages, and the number of times each manuscript was cited all significantly increased between 1986 and 2015 (p &lt; 10−4). Using the decade method, there was a significant increase in the percentage of female first authors over time from 35.8% in 1986 to 47.7% in 2015 (p = 0.02), and this trend was confirmed using the random method. The highest percentage of female first authors in 2015 was in Europe (60.0%), and Europe also had the most dramatic increase in female first authors over time (more than double in 2015 compared with 1986). Likewise, the overall number of female corresponding authors significantly increased during the past 30 years. With the increasing demands of publishing in academic medicine, understanding changes in publishing characteristics over time and by geographical region is important. These findings highlight JBMR's authorship trends over the past 30 years and demonstrate those countries having the most changes and where challenges still exist. © 2017 American Society for Bone and Mineral Research.
Capillary membrane bioreactor for abatement of low soluble compounds in waste gas
Authors: Morral Eloi , Lao‐Luque Conxita , Gabriel David , Gamisans Xavier , Dorado Antonio David 
Published: August 2017

AbstractBACKGROUNDThe removal of problematic volatile organic compounds (VOCs) from polluted gas (toluene, iso‐octane and hexane) has been investigated in a membrane bioreactor (MBR) by adapting a commercial capillary microporous polypropylene membrane. The MBR performance was measured under several operational conditions. The influence of the empty bed residence time (EBRT), the liquid velocity and the inlet concentration was evaluated.RESULTSFor toluene, it was possible to treat higher loading rates than 1600 g m‐3 h‐1 with a maximum elimination capacity (EC) of 1309 g m‐3 h‐1, removal efficiencies (RE) of ∼80%. However, iso‐octane was poorly degraded as a single pollutant. Hexane presented lower EC values (400 g m‐3 h‐1) than toluene. The synergistic effect of hexane degradation in two different mixtures was also considered.CONCLUSIONResults demonstrate that a commercial membrane for wastewater treatment can be adapted for biological gas treatment, becoming a potential alternative to conventional biological treatment technologies, especially for pollutants with low solubility. © 2017 Society of Chemical Industry
Iron(III)‐modified tungstophosphoric acid supported on silica‐pillared montmorillonite as catalysts for fructose conversion to methyl levulinate
Authors: Lai Fengjiao , Luo Jia , Jiang Dan , Su Tongchao , Zhang Fan 
Published: August 2017

AbstractBACKGROUNDBecause of the decline in conventional sources of energy and the increasing pollution, the fossil fuel based energy structures is being replaced by renewable energy based structures such as biomass energy. Among current biodiesel sources, methyl levulinate (ML) obtained from catalytic conversion of renewable carbohydrate with methanol has received a great deal of attention. Silica‐pillared montmorillonites (MMTSi) functionalized by iron‐modified tungstophosphoric acid (HPWFe) were prepared, and their physicochemical properties and catalytic effects on ML production studied.RESULTSCatalysts characterization demonstrated the high dispersion and Keggin structure of HPWFe in the framework of MMTSi. Effects of various reaction parameters and catalyst recycling on the reaction performance were studied to optimize fructose conversion. With 4‐HPWFe‐MMTSi as the catalyst, an optimized ML yield of around 74 mol% was obtained at 180°C for 1 h, and the recovered catalyst after calcination was found to retain high activity after being reused five times.CONCLUSIONThe prepared HPWFe‐MMTSi catalysts showed high porosity, perfect Brnsted‐Lewis acidity and high thermal stability, which made their catalytic activity for fructose conversion and catalyst reusability values higher than others reported in the literature. © 2017 Society of Chemical Industry
Risk factors can classify individuals who develop accelerated knee osteoarthritis: Data from the osteoarthritis initiative
Authors: Driban Jeffrey B. , McAlindon Timothy E. , Amin Mamta , Price Lori L. , Eaton Charles B. , Davis Julie E. , Lu Bing , Lo Grace H. , Duryea Jeffrey , Barbe Mary F. 
Published: August 2017

ABSTRACTWe assessed which combinations of risk factors can classify adults who develop accelerated knee osteoarthritis (KOA) or not and which factors are most important. We conducted a case‐control study using data from baseline and the first four annual visits of the Osteoarthritis Initiative. Participants had no radiographic KOA at baseline (Kellgren‐Lawrence [KL]<2). We classified three groups (matched on sex): (i) accelerated KOA: >1 knee developed advance‐stage KOA (KL = 3 or 4) within 48 months; (ii) typical KOA: >1 knee increased in radiographic scoring (excluding those with accelerated KOA); and (iii) No KOA: no change in KL grade by 48 months. We selected eight predictors: Serum concentrations for C‐reactive protein, glycated serum protein (GSP), and glucose; age; sex; body mass index; coronal tibial slope, and femorotibial alignment. We performed a classification and regression tree (CART) analysis to determine rules for classifying individuals as accelerated KOA or not (no KOA and typical KOA). The most important baseline variables for classifying individuals with incident accelerated KOA (in order of importance) were age, glucose concentrations, BMI, and static alignment. Individuals <63.5 years were likely not to develop accelerated KOA, except when overweight. Individuals >63.5 years were more likely to develop accelerated KOA except when their glucose levels were >81.98 mg/dl and they did not have varus malalignment. The unexplained variance of the CART = 69%. These analyses highlight the complex interactions among four risk factors that may classify individuals who will develop accelerated KOA but more research is needed to uncover novel risk factors. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:876–880, 2018.
Relating quality of life to outcomes and predictors in adult cochlear implant users: Are we measuring the right things?
Authors: Moberly Aaron C. , Harris Michael S. , Boyce Lauren , Vasil Kara , Wucinich Taylor , Pisoni David B. , Baxter Jodi , Ray Christin , Shafiro Valeriy 
Published: August 2017

ObjectiveCurrent clinical outcome measures for adults receiving cochlear implants (CIs) consist of word and sentence recognition, primarily under quiet conditions. However, these measures may not adequately reflect patients' CI‐specific quality of life (QOL). This study first examined traditional auditory‐only speech recognition measures and other potentially relevant auditory measures as correlates of QOL in CI users. Second, scores on nonauditory tasks of language and cognition were examined as potential predictors of QOL.Study DesignTwenty‐five postlingually deafened adults with CIs were assessed.MethodsParticipants completed a validated CI‐specific QOL measure (the Nijmegen Cochlear Implant Questionnaire) and were tested for word and sentence recognition in quiet, as well as sentence recognition in speech‐shaped noise. Participants also completed assessments of audiovisual speech recognition, environmental sound identification, and a task of complex auditory verbal processing. Several nonauditory language and cognitive tasks were examined as potential predictors of QOL.ResultsQuality‐of‐life scores significantly correlated with scores for audiovisual speech recognition and recognition of complex sentences in quiet but not sentences in noise or isolated words. No significant correlations were obtained between QOL and environmental sound identification or complex auditory verbal processing. Quality‐of‐life subdomain scores were predicted by several nonauditory language and cognitive tasks as well as some patient characteristics.ConclusionPostoperative measures of recognition of sentences in quiet and audiovisual sentence recognition correlate with CI‐related QOL. Findings suggest that sentence recognition tasks are QOL‐relevant outcomes but only explain a small fraction of the variability in QOL outcomes for this patient population.Level of Evidence4. Laryngoscope, 128:959–966, 2018
Technical Note: Using experimentally determined proton spot scanning timing parameters to accurately model beam delivery time
Authors: Shen Jiajian , Tryggestad Erik , Younkin James E. , Keole Sameer R. , Furutani Keith M. , Kang Yixiu , Herman Michael G. , Bues Martin 
Published: August 2017

PurposeTo accurately model the beam delivery time (BDT) for a synchrotron‐based proton spot scanning system using experimentally determined beam parameters.MethodsA model to simulate the proton spot delivery sequences was constructed, and BDT was calculated by summing times for layer switch, spot switch, and spot delivery. Test plans were designed to isolate and quantify the relevant beam parameters in the operation cycle of the proton beam therapy delivery system. These parameters included the layer switch time, magnet preparation and verification time, average beam scanning speeds in x‐ and y‐directions, proton spill rate, and maximum charge and maximum extraction time for each spill. The experimentally determined parameters, as well as the nominal values initially provided by the vendor, served as inputs to the model to predict BDTs for 602 clinical proton beam deliveries. The calculated BDTs (TBDT) were compared with the BDTs recorded in the treatment delivery log files (TLog): ∆t = TLog−TBDT.ResultsThe experimentally determined average layer switch time for all 97 energies was 1.91 s (ranging from 1.9 to 2.0 s for beam energies from 71.3 to 228.8 MeV), average magnet preparation and verification time was 1.93 ms, the average scanning speeds were 5.9 m/s in x‐direction and 19.3 m/s in y‐direction, the proton spill rate was 8.7 MU/s, and the maximum proton charge available for one acceleration is 2.0 ± 0.4 nC. Some of the measured parameters differed from the nominal values provided by the vendor. The calculated BDTs using experimentally determined parameters matched the recorded BDTs of 602 beam deliveries (∆t = −0.49 ± 1.44 s), which were significantly more accurate than BDTs calculated using nominal timing parameters (∆t = −7.48 ± 6.97 s).ConclusionsAn accurate model for BDT prediction was achieved by using the experimentally determined proton beam therapy delivery parameters, which may be useful in modeling the interplay effect and patient throughput. The model may provide guidance on how to effectively reduce BDT and may be used to identifying deteriorating machine performance.