bluuebunny/crossref_metadata_2025_split huggingface dataset:
Macrophage activity modulation via synergistic effect of a porous substrate and low-field laser therapy
Authors: Ścisłowska-Czarnecka Anna , Matuła Aleksandra , Lizak Amelia , Stodola-Zych Ewa , Stenka Beata , Homa Joanna , Bac Aneta , Teległów Aneta 
Published: September 2024

Purpose
The aim of this study was to investigate the effect of substrate - polycaprolactone (PCL) based porous membrane modified with rosmarinic acid (RA), (PCL-RA) and to determine the optimal values of low field laser irradiation (LLLT) as stimulators of biological response of RAW 264.7 macrophages.
Methods
The porous polymer membrane was obtained by the phase inversion method, the addition of rosmarinic acid was 1%wt. The reference material was pure polymer membrane. RAW 264.7 were deposited on the material and then irradiated with a laser with a wavelength of 808 nm, a power of 100 mW, an irradiation dose of 2 J/cm2/cell well, applied continuously (C), (100/2/C) or pulsed (I), (100/2/I).
Results
Macrophage irradiation resulted in an increase their adhesion. Modifying the PCL membranes with rosmarinic acid had no effect on cell viability on day 3 of the cell culture. Irradiation of macrophages cultured on PCL-RA material increased their viability. Irradiation of macrophages cultured on PCL-RA material decreased macrophage secretion of NO and protein and the increase in TNF and MCP-1 secretion was only transient on day 3 of culture.
Conclusions
Macrophage irradiation had a positive effect on macrophage attachment. Modification of PCL membranes with rosmarinic acid influenced the biological activity of macrophages. Culture of macrophages on rosmarinic acid-modified PCL membranes and simultaneous irradiation of LLLT cells resulted in anti-inflammatory effects.
Dynamic characteristics of a compliant seat coupled with the human body and a manikin during the exposure to the whole-body vibration: Effect of the polyurethane foam, the track position, and the measurement location
Authors: Xiaolu Zhang  , Sen Lin  , Xichen Song  , Chi Liu  , Yi Qiu  
Published: September 2024

Purpose
Transmissibility is used to assess dynamic responses of the occupant-seat system, and most studies have exclusively assessed the transmissibility from the floor to the cushion or the backrest surface with the human body.
Methods
In this investigation, the vertical vibration transmitted from the floor to six specific locations both on the seat surface and the frame when the seat was fixed on three positions on the track was examined utilizing an SAE J826 manikin and 12 male adults (0.25 to 20 Hz) for a duration of 120 seconds at three vibration amplitudes.
Results
The transmissibility from the floor to the headrest frame, the cushion surface, the headrest surface, the seat back frame, and the seat back surface all exhibited a principal peak frequency within 4-5 Hz. With the exception of the cushion frame, the principal peak frequency and the peak transmissibility in transmissibilities to all positions decreased with increasing vibration amplitude, indicating the non-linearity within the occupant-seat system. It was also found modifying seat track positions minimally affected the seat transmissibility to either the surface or the frame of the seat.
Conclusions
Polyurethane foam amplified vibration at peak frequency, simultaneously enhancing static sitting comfort and reducing the vertical vibration transmission above peak frequency.
Determinants of Islamic Banks' Profitability in an Emerging Economy
Authors: Hossain Mohammad Azhar 
Published: September 2024

Purpose: This study investigates the factors influencing the profitability of Sharia-based Islamic banks operating in Bangladesh.
Methods: Using panel data from 2017 to 2023, the current analysis shows how factors particular to individual banks have impacted the profitability of Bangladeshi banks. To complete this analysis, only Islamic banks are taken into consideration. In this paper, the factors that affect Bangladesh's Islamic banking industry's profitability are clarified. 10 Islamic banks operating in Bangladesh are included in the sample. The study investigates internal factors such as size, liquidity risk, operational effectiveness, credit risk, financial risk, and capital adequacy. The analysis is conducted using panel data regression with fixed effect.
Results: The result shows that operating efficiency, financial risk, and liquidity risk are the most relevant bank-specific characteristics in determining the Islamic banks’ profitability in Bangladesh.
Implications: The study suggests that bankers should keep a close observation of credit and liquidity risk indicators, diversify their revenue streams, and minimize expenses. Moreover from the regulatory perspective, the performance of the banks should be evaluated based on their operational efficiency and ability to generate profit. The policy direction will be directed towards enhancing resilience by reducing the risk internally and increasing the efficiency of the Islamic banks to intensify the robustness and stability of this sector.
Originality: While numerous previous studies have provided various explanations of the factors influencing bank profitability, this research specifically examines the internal factors affecting the profitability of Islamic Banks in Bangladesh, an emerging market.
Unveiling Subarcsecond Multiplicity in the Pleiades with Gaia Multicolor Photometry
Authors: Chulkov Dmitry 
Published: September 2024

Abstract
The list of 409 probable cluster members down to G = 15mag (m ≳ 0.5M
⊙) is compiled for the two degree radius of the Pleiades, based on astrometric data from Gaia DR3 and the PPMXL catalog, along with several radial velocity surveys, including APOGEE and LAMOST. This approach allows for the inclusion of binary stars with unreliable Gaia solutions, thereby eliminating associated bias. Thus, the often-neglected 14 sources with Gaia two-parameter solutions are included. The subsequent analysis of color–magnitude and color–color diagrams exploits artifacts in Gaia photometric data, caused by the different field sizes used to measure fluxes in the G, B

p
, and R

p
passbands, to reveal binary stars with subarcsecond angular separation. The findings are validated with prior high-resolution observations. Overall, 24 ± 3 cluster members with angular separation between 0.″1 and 1″ (13.5–135 au projected distance) and mass ratio q > 0.5 are deemed binary, indicating a binarity fraction of 6 ± 1%.
Resolving Twin Jets and Twin Disks with JWST and ALMA: The Young WL 20 Multiple System
Authors: Barsony Mary , Ressler Michael E. , Le Gouellec Valentin J. M. , Tychoniec Łukasz , van Gelder Martijn L. 
Published: September 2024

Abstract
We report the discovery of jets emanating from pre-main-sequence objects exclusively at mid-infrared wavelengths, enabled by the superb sensitivity of JWST’s Mid-Infrared Instrument Medium-Resolution Spectrometer. These jets are observed only in lines of [Ni ii], [Fe ii], [Ar ii], and [Ne ii]. The H2 emission, imaged in eight distinct transitions, has a completely different morphology, exhibiting a wide-angled, biconical shape, symmetrically distributed about the jet axes. Synergistic high-resolution Atacama Large Millimeter/submillimeter Array (ALMA) observations resolve a pair of side-by-side edge-on accretion disks lying at the origin of the twin mid-infrared jets. Assuming coevality of the components of the young multiple system under investigation, the system age is at least (2–2.5) × 106 yr, despite the discrepantly younger age inferred from the spectral energy distribution of the combined edge-on disk sources. The later system evolutionary stage is corroborated by ALMA observations of CO(2−1), 13CO(2−1), and C18O(2−1), which show no traces of molecular outflows or remnant cavity walls. Consequently, the observed H2 structures must have their origins in wide-angled disk winds, in the absence of any ambient, swept-up gas. In the context of recent studies of protostars, we propose an outflow evolutionary scenario in which the molecular gas component dominates in the youngest sources, whereas the fast, ionized jets dominate in the oldest sources, as is the case for the twin jets discovered in the WL 20 system.
Playing with FIRE: A Galactic Feedback-halting Experiment Challenges Star Formation Rate Theories
Authors: Khullar Shivan , Matzner Christopher D. , Murray Norman , Grudić Michael Y. , Guszejnov Dávid , Wetzel Andrew , Hopkins Philip F. 
Published: September 2024

Abstract
Stellar feedback influences the star formation rate (SFR) and the interstellar medium of galaxies in ways that are difficult to quantify numerically, because feedback is an essential ingredient of realistic simulations. To overcome this, we conduct a feedback-halting experiment starting with a Milky Way–mass galaxy in the second-generation Feedback In Realistic Environments (FIRE-2) simulation framework. By terminating feedback, and comparing to a simulation in which feedback is maintained, we monitor how the runs diverge. We find that without feedback, the interstellar turbulent velocities decay. There is a marked increase of dense material, while the SFR increases by over an order of magnitude. Importantly, this SFR boost is a factor of ∼15–20 larger than is accounted for by the increased freefall rate caused by higher densities. This implies that feedback moderates the star formation efficiency per freefall time more directly than simply through the density distribution. To probe changes at the scale of giant molecular clouds (GMCs), we identify GMCs using density and virial parameter thresholds, tracking clouds as the galaxy evolves. Halting feedback stimulates rapid changes, including a proliferation of new bound clouds, a decrease of turbulent support in loosely bound clouds, an overall increase in cloud densities, and a surge of internal star formation. Computing the cloud-integrated SFR using several theories of turbulence regulation, we show that these theories underpredict the surge in SFR by at least a factor of 3. We conclude that galactic star formation is essentially feedback regulated on scales that include GMCs, and that stellar feedback affects GMCs in multiple ways.
Pas de cuisine sans casserole. Quand la résonance crée les sonorités d’une symphonie de guérison
Authors: Brandibas Gilles 
Published: September 2024

Les casseroles sont cette métaphore que nous utilisons dans le langage familier pour signifier la référence aux blessures personnelles, qu’elles soient celles des personnes accompagnées ou celles des professionnelles. Nous avons voulu proposer dans cet article une réflexion, celle de la rencontre de ces fameuses casseroles. Nos blessures respectives rentrent-elles en résonance et de quelle manière ? C’est ce que nous avons essayé de décliner en y ajoutant quelques pistes de réponses.
Marmites. Un atelier d’écriture qui cuisine la culture
Authors: Lebrun Léo , Bounaas Louisa , Beltram Kilian 
Published: September 2024

Inspiré par un mot utilisé dans un dispositif de médiation ethnoclinique, un formateur propose à des étudiants en travail social d’écrire sur leurs « marmites ». Récit de praticien, ce texte tissé à partir de textes d’étudiants explore ce que rend possible l’écriture de soi en formation de travailleur social.
Interroger la notion de « Jeunes en errance »
Authors: Chobeaux François 
Published: September 2024

Voici près de 35 ans que le terme « Jeunes en errance » a été proposé et est depuis utilisé dans les milieux du travail social et des politiques publiques. Mais peu à peu ce terme, et plus simplement le terme « Errance », ont servi à qualifier de plus en plus de dynamiques de vie et de comportements sociaux, concernant des publics de plus en plus divers. Cet article propose de revenir sur les utilisations de ce terme, d’entrevoir les effets de cet usage, et en suggère un usage plus précis.
Comparison of the Analgesic Duration Using Ultrasound-guided Popliteal Sciatic Nerve Block between Diabetics with Neuropathy and Nondiabetics without Neuropathy
Authors: Prasad Ganesh , Misquith Julie C. R. , Ribeiro Karl Nicholas Sa , Naik Shilpa A. 
Published: September 2024

Introduction:
In India, the prevalence of diabetes mellitus neuropathy was reported to be as high as 30%. Eight percentage of the diabetic population suffer from foot ulceration and 1.8% have amputations. Popliteal nerve block can be potentially used for foot and ankle surgery with several advantages.

Aim:
To compare analgesic duration of an ultrasound (US)-guided popliteal sciatic nerve block between diabetics with neuropathy and nondiabetics without neuropathy.

Patients and Methods:
Participants were allocated into two groups for popliteal sciatic nerve blocks under US guidance. The primary outcome was the duration to onset of sensory and motor blockade. The secondary outcome was the duration to rescue analgesic and the visual analog scale scoring within 24 h. Hemodynamic outcomes were also monitored along with the above variables.

Results:
It was observed that the onset of sensory blockade was faster in participants with diabetes mellitus with peripheral neuropathy as compared to the nondiabetic participants and the duration for onset of motor blockade in dorsiflexion was faster in diabetic patients as compared to the nondiabetic patients (17.48 ± 3.21 min). However, there was no significant changes when comparing the onset of duration to loss of plantar flexion, in diabetics (17.86 ± 2.29 min) versus in nondiabetics (18.51 ± 3.32 min). The duration for rescue analgesics was found to be longer in diabetic participants (13.19 ± 2.14 h) as compared to the nondiabetic participants (11.44 ± 1.86 h). No differences were observed in the hemodynamic changes and the complications associated with local anesthetics in either group.

Conclusion:
Diabetic patients with neuropathy have faster onset of blockade when compared to nondiabetic patients without neuropathy which may be due to the degenerative condition of the peripheral nerves in them. The hemodynamic parameters do not play a role in defining the outcome of the block.
Application of topical minoxidil in acne vulgaris treatment
Authors: Chen Chun-Bing , Kuo Yung-Chia , Chang Sun-Min , Lin An-Chi , Fan Hsien-Chi , Lin Tung-Liang , Chung Wen-Hung , Hsu Cheng-Lung 
Published: September 2024

Abstract

Background:
Acne vulgaris (AV) results from increased sebum production and Cutibacterium acnes (C. acnes) overgrowth, leading to pilosebaceous unit inflammation. The androgen-androgen receptor (AR) pathway significantly contributes to acne development, with minoxidil showing promise in suppressing AR-related activities.

Objectives:
This study aims to examine the mechanism and effectiveness of minoxidil in treating AV.

Methods:
The effects of minoxidil on lipid metabolism and bacterial infection/inflammation were tested. A clinical trial was performed to evaluate the effect of topical minoxidil on AV.

Results:
Minoxidil suppressed fatty acid synthase activity and lipid formation in an androgen-sensitive prostate cancer cell line in vitro and sebum formation in hamster flank organs in vivo. For C. acnes, minoxidil had a half-maximum inhibitory concentration of 5 mM. Both 2% and 5% minoxidil suppressed C. acnes-induced infection/inflammation in an animal model. A phase I/II clinical trial of topical minoxidil in treating AV using a split-face model demonstrated a good response and well-tolerated side effects. Compared to the untreated side, the numbers of all types of lesions decreased significantly on the treated side on day 3 (mean: −2.238, 95% confidence interval [CI]: −3.821 to −0.655, P = 0.008), day 8, and reached the maximum effect on day 15 (mean: −1.286, 95% CI: −2.151 to −0.420, P = 0.006). Responders to topical minoxidil may experience rapid regression of acne as early as 3 days of treatment.

Conclusion:
Our collective data indicate that minoxidil could inhibit AR-related functions and C. acnes growth in treating AV.
Evaluation of arthroscopic ankle fusion for diabetic ankle fractures
Authors: Erfan Hossam Tarek Ali , El Tabbaa Ayman Yousef , Samy Ahmed , El-Rosasy Mahmoud Abdel-Monem 
Published: September 2024

Background
Ankle fractures are a very common orthopedic trauma. One in eight patients undergoing ankle fixation is diabetic. Most of these patients also have additional comorbidities including peripheral arterial disease and diabetic neuropathy. Therefore, on one hand surgical intervention can pose challenges for wound healing and risk of infection, but non-operative management increases the risk for loss of reduction and therefore stresses the condition of the surrounding soft tissue. The aim of this work was to observe the radiological and functional outcome of arthroscopic ankle fusion in diabetic ankle fractures.

Methods
This prospective study was carried out on 20 patients, both sexes, with clinical criteria of displaced ankle fractures in diabetics, adults, closed ankle fractures, isolated trauma, diabetic patients with neuropathy and Adelaide Fracture in the Diabetic Ankle score more than or equal 5.

Results
Fourteen cases had solid bony union at a mean of 27.2 weeks while six cases had stable ankles with stiff fibrous nonunion at the end of the follow up period. Two of which had a breakage of distal locking screws. However, stiff fibrous nonunion of tibio-talar joint with the foot in a stable plantigrade position was considered satisfactory and no further intervention was advised. Our limb salvage rate was 100%. No below knee amputation was done.

Conclusions
Ankle fractures in diabetic patients are increasingly frequently encountered in comorbid patients with suboptimal overlying soft tissue integrity. Arthroscopic assisted ankle fusion can be considered a valid primary definitive treatment option to help reduce the potential perioperative soft tissue insult and associated complications. Utilizing an arthroscopic-assisted approach to this procedure is of added benefit in allowing for articular preparation and thereby reducing the risk of non-union while also minimizing additional extensive soft tissue insult in patients with underlying soft tissue compromise.
Calcaneotalotibial arthrodesis by retrograde intramedullary nailing for Charcot osteo-neuroarthropathy of the foot and ankle
Authors: Kholeif Ahmed M. , Hassan Ahmed S. , Ghani Hatem A. 
Published: September 2024

Background
The Charcot’s foot and ankle presents a significant and complex clinical challenge for foot and ankle surgeons. Neuropathic arthropathy of the foot and ankle is a degenerative deformity that gradually worsens over time. It is most frequently observed in individuals with diabetic neuropathy.

Aim and objectives
To evaluate the efficacy, advantages, and disadvantages of calcaneotalotibial arthrodesis by retrograde intramedullary nailing for Charcot osteo-neuroarthropathy of the ankle.

Patients and methods
This prospective research was done on 20 cases with Charcot osteoarthropathy of the ankle using calcaneotalotibial interlocking nails at Helwan University Hospital, Al Helal Hospital, Boulak El Dakror General Hospital, and Kasr Al Ainy Hospital during the period between January 2021 and January 2022.

Results
Patients had both types of diabetes mellitus. As regard complications, they occurred in seven (35%) patients as follows: one patient had an intraoperative distal tibial crack during nail introduction, two patients had loosening of proximal screws and infection, three patients had skin infection at the site of distal screws, and one patient had deep infection improved with parenteral antibiotics. There was a statistically significant improvement in the American Orthopedic Foot and Ankle Society score among the studied patients with a P value less than 0.001.

Conclusion
We observed a satisfactory result in the treatment of severe abnormalities of the ankle and hind foot in Charcot neuroarthropathy utilizing the retrograde intramedullary arthrodesis nail. The transcalcaneal retrograde intramedullary represents a safe and efficacious fixation option.
Implant-supported prosthesis rehabilitation for a completely edentulous patient with digital workflow – Clinical case report
Authors: Chandraker Neeraj Kumar , Chander Naveen Gopi , Jha Anumeha , Kerketta Jenifer , Chandraker Rashmi 
Published: September 2024

ABSTRACT
The literature documents the implementation of digital workflow for rehabilitating edentulous conditions with implant-supported prostheses. However, various factors limit its implementation in completely edentulous conditions, especially in impression-making and jaw relations recording. This clinical case report describes rehabilitating a completely edentulous patient with an implant-supported prosthesis using a comprehensive digital workflow. Furthermore, it provides an overview of the technical difficulties and limitations of the technology during the process.
Mandibular complete denture converted to a total fixed implant-supported prosthesis using a distal extension bar: A protocol modification
Authors: Neves Flávio Domingues Das , Peixoto Ana Carolina Candelas , Rocha Luísa de Lanna Reis , Santos Fábio Henrique de Paulo Costa , Zancopé Karla 
Published: September 2024

ABSTRACT
For total immediate occlusal loading (IOL) implant protocol cases, a reinforcement in the distal portion is necessary. Initially called IOL component, the distal extension bar is indicated for patients who use removable dentures and for patients who need multiple extractions. The main advantage of the distal extension bar is that it permits denture capture directly over the abutments. Converting the removable denture to an implant-supported treatment avoids psychological or functional trauma from wearing dentures during this interim phase and does not transmit undesirable pressure to the submerged implants. In addition, the use of a distal extension bar gives the cantilever region of the temporary protocol prosthesis, which is weak because it lacks a metal framework that internally unites all the teeth as in the definitive protocol prosthesis, more strength. Therefore, the purpose of this article is to describe a case report of a mandibular protocol using a distal extension bar with a modification of the manufacturers’ protocol.
Evaluation of Animal Birth Control Program in an Urban Area of North Kerala
Authors: Amrutha D. , Chandran Priya , Sreeshma V. S. 
Published: September 2024

Background:
India contributes to 36% of global rabies-related deaths, according to the World Health Organization. To address the issue of increased number of stray dog exposures, the Kerala Government initiated a comprehensive plan that includes an intensive animal birth control (ABC) program along with antirabies vaccination. This study was conducted with the objective of evaluating the implementation of the ABC program in the corporation area of Kozhikode district.

Materials and Methods:
Evaluation of the ABC program was performed based on the Standard Operating Procedures proposed by the Animal Welfare Board of India. The program was evaluated using input–output analysis.

Results:
The input indicators included the infrastructure, workforce, equipment, and logistics for the conduct of the program. As per a survey conducted in Kozhikode Municipal Corporation in 2018, there were 13,182 ± 1612 stray dogs. The program includes sterilization and vaccination, as well as pet dog licensing and microchipping services. Even though a remarkable reduction in animal exposures is not seen in corporation area, not much cases of human rabies were reported.

Conclusion:
A single ABC clinic catering to a large population may not be enough to meet the increasing stray dog population. Achievements gained by the program may be diluted due to insufficient workforce and procedures. Sustained coverage of ABC programs to some extent can solve the frequent shortages of vaccines and hence the increased dependence on PEP which is overburdening the health system. The program may be expanded to rural areas also.