bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Stereoselective Ag‐Catalyzed 1,3‐Dipolar Cycloaddition of Activated Trifluoromethyl‐Substituted Azomethine Ylides.
Authors: Ponce Alberto , Alonso Ines , Adrio Javier , Carretero Juan C. 
Published: July 2016

AbstractThe Ag‐catalyzed 1,3‐dipolar cycloaddition of fluorinated azomethine ylides with a variety of olefins results in a highly endo‐diastereoselective synthesis of β‐trifluoromethyl pyrrolidines.
ChemInform Abstract: Alkaline‐Earth‐Catalyzed sp3 C—H Functionalization of Methyl Azaarenes and Its Use in a One‐Pot Four‐Component Synthesis of Azaarenyl Benzylpyrazolones.
Authors: Yaragorla Srinivasarao , Dada Ravikrishna , Singh Garima 
Published: July 2016

AbstractFor the first time, calcium triflate is used to catalyze a 4‐component reaction between aldehydes, 2‐methylquinolines, ethyl acetoacetate, and arylhydrazines to give 1‐aryl‐3‐methyl‐4‐ [2‐(quinolin‐2‐yl)‐1‐aryl/alkyl‐ethyl]‐2H‐pyrazol‐5‐ones.
ChemInform Abstract: Nitrone Cycloadditions of 1,2‐Cyclohexadiene.
Authors: Barber Joyann S. , Styduhar Evan D. , Pham Hung V. , McMahon Travis C. , Houk K. N. , Garg Neil K. 
Published: July 2016

AbstractThe first 1,3‐dipolar cycloaddition of in situ generated 1,2‐cyclohexadiene is reported, which occurs regioselectively and with notable endo preference, resulting in the controlled formation of two new bonds and two stereogenic centers.
ChemInform Abstract: Iodine Catalyzed Simple and Efficient Synthesis of Antiproliferative 2‐Pyridones.
Authors: Buduma Komuraiah , Chinde Srinivas , Arigari Niranjana Kumar , Grover Paramjit , Srinivas K. V. N. S. , Kotesh Kumar J. 
Published: July 2016

AbstractA simple and efficient method for the selective synthesis of 2‐pyridones (II) (13 examples) from corresponding 4H‐pyrans (I) is developed.
ChemInform Abstract: Direct Alkenylation of Alkylazaarenes with Aldehydes Through C(sp3)—H Functionalization under Catalytic InCl3 Activation.
Authors: Jamal Zaini , Teo Yong‐Chua , Lim Gina Shiyun 
Published: July 2016

AbstractThe direct alkenylation of primary and secondary benzylic C—H bonds of alkylquinoline derivatives with aldehydes is achieved in the presence of InCl3 as the catalyst.
ChemInform Abstract: Manganese(II)‐Catalyzed Modular Synthesis of Isoquinolines from Vinyl Isocyanides and Hydrazines.
Authors: Mao Hong , Gao Mingchun , Liu Bingxin , Xu Bin 
Published: July 2016

AbstractA novel method for the preparation of isoquinolines by a Mn‐catalyzed oxidative cyclization of vinyl isocyanides with hydrazines is elaborated.
ChemInform Abstract: Three‐Component Domino Cyclization of Novel Carbazole and Indole Fused Pyrano[2,3‐c]pyridine Derivatives.
Authors: Zhang Wenhui , Wang Jianqiang , Mao Jingpeng , Hu Li , Wu Xiaohua , Guo Cheng 
Published: July 2016

AbstractA facile and reliable three‐component intramolecular six‐membered heterocyclization as an alternative method for the efficient synthesis of fused carbazole and indole pyrano[2,3‐c]‐pyridine derivatives is reported, starting from commercially available hydroxycarbazole or hydroxyindole with diverse aromatic aldehydes and aminopropenetricarbonitrile.
ChemInform Abstract: Sequential Ketene Generation from Dioxane‐4,6‐dione‐keto‐dioxinones for the Synthesis of Terpenoid Resorcylates.
Authors: Elliott Daniel C. , Ma Tsz‐Kan , Selmani Aymane , Cookson Rosa , Parsons Philip J. , Barrett Anthony G. M. 
Published: July 2016

AbstractKiegiel‐type reaction of alcohols with the ketene generated in situ by thermolysis of compound (I) furnishes dioxinone‐β‐ketoesters which are transformed into the title compounds by Pd(0)‐catalyzed decarboxylative allyl migration and aromatization.
ChemInform Abstract: Bismuth Acetate as a Catalyst for the Sequential Protodeboronation of Di‐ and Triborylated Indoles.
Authors: Shen Fangyi , Tyagarajan Sriram , Perera Damith , Krska Shane W. , Maligres Peter E. , Smith Milton R. , Maleczka Robert E. Jr. 
Published: July 2016

AbstractAn iridium‐catalyzed preparation of mono‐, di‐ and triborylated indole derivatives followed by bismuth‐ or iridium‐catalyzed protodeborylation is described which allows for the regioselective synthesis of 4‐, 5‐ or 7‐monoborylated, 2,7‐, 4,7‐ and 3,5‐diborylated as well as 2,4,7‐triborylated indole derivatives.
ChemInform Abstract: Facile and Highly Selective Silylation of Vinylpyridines at the β‐Olefinic Carbon by Magnesium‐Promoted Reduction.
Authors: Zhang Tianyuan , Zhang Zeyu , Nishiyama Yutaro , Maekawa Hirofumi 
Published: July 2016

AbstractThe Mg‐promoted reductive silylation of 2‐ and 4‐vinylpyridines gives rise to the formation of the corresponding β‐mono‐silylated compounds.
ChemInform Abstract: Non‐Precious‐Metal Catalytic Systems Involving Iron or Cobalt Carboxylates and Alkyl Isocyanides for Hydrosilylation of Alkenes with Hydrosiloxanes.
Authors: Noda Daisuke , Tahara Atsushi , Sunada Yusuke , Nagashima Hideo 
Published: July 2016

AbstractThe catalyst systems are expected to be applicable to industrial processes for modification of silicon fluids and generation of silicon gels.
ChemInform Abstract: Silver(I)‐Mediated Phosphorylation/Cyclization Cascade of N‐Cyanamide Alkenes for Divergent Access to Quinazolinones and Dihydroisoquinolinones.
Authors: Zheng Jing , Zhang Yan , Wang Dahai , Cui Sunliang 
Published: July 2016

AbstractAg‐Mediated divergent phosphorylation/cyclization cascade of N‐cyanamide alkenes is developed.
ChemInform Abstract: Three New Atisane Diterpenoids from Spiraea japonica.
Authors: Qin Xiang‐Dong , Yang Shu , Zhao Yan , Wang Li‐Xia , Ren Fu‐Cai , Wang Fei 
Published: July 2016

AbstractThree new atisane diterpenoids, spiratisanin A (Ia), spiratisanin B (Ib), and spiratisanin C (II) are isolated from the whole plant of Spiraea japonica together with two known atisine diterpene alkaloids.
ChemInform Abstract: One Pot InCl3‐Catalyzed Synthesis of 1‐Glycosylmethyl‐1H‐imidazoles.
Authors: Petrusova Maria , Smrticova Hana , Pribulova Bozena , Vlckova Silvia , Uhliarikova Iveta , Docsa Tibor , Somsak Laszlo , Petrus Ladislav 
Published: July 2016

AbstractA simple protocol allows the four component condensation of six different C‐glycosyl methylamines, 1,2‐diketones, formaldehyde, and ammonium acetate to give imidazole substituted products such as (IV).
ChemInform Abstract: Three New Lycopodium Alkaloids from Phlegmariurus fargesii.
Authors: Hao Li‐Jun , Zhou Yun‐Jing , Wang Lu‐Lu , Pan Ke 
Published: July 2016

AbstractThree new Lycopodium alkaloids fargesiine A (Ia), fargesiine B (Ib), and fargesiine C (II) are isolated from Phlegmariurus fargesii together with one known compound.
ChemInform Abstract: Synthesis of (.+‐.)‐Bisavenanthramide B‐6 by an Anionic Anhydride Mannich Reaction.
Authors: Di Maso Michael J. , Nepomuceno Gabriella M. , St. Peter Michael A. , Gitre Haley H. , Martin Kevin S. , Shaw Jared T. 
Published: July 2016

AbstractThe first anionic anhydride Mannich reaction and its application to the densely substituted core of the complex natural product, bisavenanthramide B‐6 (V) is described.
ChemInform Abstract: Pseudonocardides A—G, New γ‐Butyrolactones from Marine‐Derived Pseudonocardia sp. YIM M13669.
Authors: Zhang Xiao‐Mei , Zhang Dao‐Feng , Li Wen‐Jun , Lu Chun‐Hua 
Published: July 2016

AbstractThe new γ‐butyrolactones pseudonocardides A—G (I)—(VII) are isolated from marine‐derived Pseudonocardia sp.
Cellulose Aerogel Fibers Tested on a REXUS 18 Rocket – The ACTOR Project
Authors: Schulz Björn , Meinert Tobias , Bierbüsse David , Busen Michel , Körtzinger Nina , Stankowski Michael , Seide Gunnar 
Published: July 2016

AbstractAerogels are high‐performance materials used for space and aviation purposes. Cellulose aerogel fibers have been investigated under real space conditions for their insulation properties. The experiments were carried out in a one‐stage high‐altitude research rocket of the improved ORION type. A cuboid module with measurement cells, camera modules, and electronic devices has been developed for monitoring the insulation behavior of cellulose aerogel non‐woven samples. The thermal behavior of these samples has been analyzed and compared to cellulose cloth (cotton) and aluminum for reference.
The Plug & Play Reactor: A Highly Flexible Device for Heterogeneous Reactions in Continuous Flow
Authors: Lichtenegger Georg J. , Tursic Vitan , Kitzler Hannes , Obermaier Klemens , Khinast Johannes G. , Gruber‐Wölfler Heidrun 
Published: July 2016

AbstractThe so‐called plug & play reactor is a novel reaction device with exchangeable reaction segments as well as modules for heating/cooling and mixing. Its performance is demonstrated for two model processes: the production of acetylsalicylic acid with a fixed bed of commercial ion‐exchange particles and a Suzuki‐Miyaura cross‐coupling with a solid Pd‐catalyst developed by us. The reaction progress was monitored by inline UV‐vis spectroscopy and compared with offline HPLC. The novel set‐up leads to quantitative yields and selectivity as well as to an improved practicability of the processes.
Crystallization of Nano‐Calcium Carbonate: The Influence of Process Parameters
Authors: Aldea Steliana , Snåre Mathias , Eränen Kari , Grenman Henrik , Rautio Anne‐Riikka , Kordás Krisztian , Mikkola Jyri‐Pekka , Salmi Tapio , Murzin Dmitry Y. 
Published: July 2016

AbstractPrecipitated calcium carbonate was synthesized by carbonation of calcium hydroxide in the presence and absence of ultrasound (conventional stirring) at atmospheric as well as at elevated pressures and different initial concentrations of Ca(OH)2. Spherical morphology of the formed calcite was favored at high Ca(OH)2 concentrations and low CO2 pressures. The presence of ultrasound did not show any influence on the reaction rate in case of efficient mixing. A small increase of the reaction rate was observed at lower CO2 pressures. Elevated pressures in combination with ultrasound did not lead to notable changes of reaction rate or particle morphology.
Photoanode/Electrolyte Interface Stability in Aqueous Dye‐Sensitized Solar Cells
Authors: Galliano Simone , Bella Federico , Gerbaldi Claudio , Falco Marisa , Viscardi Guido , Grätzel Michael , Barolo Claudia 
Published: July 2016

AbstractO'Regan and Grätzel conceived a dye‐sensitized solar cell (DSSC), which operates as an artificial photosynthetic system converting solar light into electricity. Nevertheless, it is only recently that the scientific community is focusing on truly aqueous DSSCs that use water as electrolyte, thus avoiding any flammable and toxic organic solvents. The most critical aspect of these devices is the photoanode/electrolyte interface. Indeed, it is necessary to select dyes that chemisorb onto the semiconductor layer while allowing the aqueous electrolyte to thoroughly impregnate the mesostructure of the electrode; at the same time, it is necessary to avoid the anchoring unit of the dye to be hydrolyzed by water, thus causing the detachment of the sensitizer from the active material particles. This requires a thorough analysis of the structure–property relationships, in particular the evaluation of the chemical formula, stability, and performances of the dyes on the electrode surface in truly aqueous environment. Herein, we investigate nine different sensitizers, selected based on their different properties in terms of light absorption, chemical structure, and hydrophobic/hydrophilic nature. Wettability, resistance to dye desorption, and spectral variations of sensitized photoanodes, along with the photovoltaic performance of the resulting devices, are systematically investigated to identify some useful guidelines to choose and design suitable dyes of different colors for truly aqueous DSSCs.
A fully discrete ALE method over untwisted time–space control volumes
Authors: Qi Jin , Li Jiequan 
Published: July 2016

SummaryIn this paper, a fully discrete high‐resolution arbitrary Lagrangian–Eulerian (ALE) method is developed over untwisted time–space control volumes. In the framework of the finite volume method, 2D Euler equations are discretized over untwisted moving control volumes, and the resulting numerical flux is computed using the generalized Riemann problem solver. Then, the fluid flows between meshes at two successive time steps can be updated without a remapping process in the classic ALE method. This remapping‐free ALE method directly couples the mesh motion into a physical variable update to reflect the temporal evolution in the whole process. An untwisted moving mesh is generated in terms of the vorticity‐free part of the fluid velocity according to the Helmholtz theorem. Some typical numerical tests show the competitive performance of the current method. Copyright © 2016 John Wiley & Sons, Ltd.
Snow hydrology signatures for model identification within a limits‐of‐acceptability approach
Authors: Schaefli Bettina 
Published: July 2016

AbstractDischarge simulation from snow‐dominated catchments seems to be an easy task. Any spatially explicit precipitation–runoff model coupled to a temperature‐index snow model generally yields simulations that mimic well the observed daily discharges. The robustness of such models is, however, questionable: in the presence of strong annual discharge cycles, small model residuals do not guarantee high explanatory power of the underlying model. This paper proposes a methodology for snow hydrological model identification within a limits‐of‐acceptability framework, where acceptable model simulations are the ones that reproduce a set of signatures within an a priori specified range. The signatures proposed here namely include the relationship between the air temperature regime and the discharge regime, a new snow hydrology signature that can be readily transferred to other Alpine settings. The discriminatory power of all analysed signatures is assessed with a new measure of their discriminatory power in the model prediction domain. The value of the proposed snow hydrology signatures and of the limits‐of‐acceptability approach is demonstrated for the Dischma river in Switzerland, whose discharge shows a strong temporal variability of hydrologic forcing conditions over the last 30 years. The signature‐based model identification for this case study leads to the surprising conclusion that the observed discharge data contains a multi‐year period that cannot be reproduced with the model at hand. This model‐data mismatch might well result from a yet to be identified problem with the discharge observations, which would have been difficult to detect in a classical residual‐based model identification approach. Overall, the detailed results for this case study underline the robustness of the limits‐of‐acceptability approach in the presence of error‐prone observations if it is applied in combination with relatively robust signatures. Future work will show whether snow hydrology signatures and their limits‐of‐acceptability can be regionalized to ungauged catchments, which would make this model selection approach particularly powerful for Alpine environments. Copyright © 2016 John Wiley & Sons, Ltd.
Does cefuroxime alter fracture healing in vivo? A micro‐computertomographic, biomechanical, and histomorphometric evaluation using a rat fracture model
Authors: Bissinger Oliver , Kreutzer Kilian , Wolff Klaus‐Dietrich , Wexel Gabriele , Hapfelmeier Alexander , Pautke Christoph , Vogt Stephan , Michael Prodinger Peter , Tischer Thomas 
Published: July 2016

AbstractCefuroxime is widely used for antibiotic prophylaxis in orthopedic surgery. However, a recent study indicated a dose‐dependent reduction in osteoblast function in vitro. Nevertheless, cell culture might not sufficiently imitate the complex process of bone remodeling. As data concerning possible in vivo interactions of cefuroxime on fracture healing are completely missing, we investigated the following hypothesis: Does Cefuroxime impair bone healing in vivo? Therefore, 34 male Wistar rats were randomised to cefuroxime‐treated or control groups, a Kirschner wire was inserted into right femora and closed transverse fractures were produced. Twenty‐one days later, the structural properties of the fracture callus in the early fracture healing phase were evaluated via a combination of micro‐CT (μCT), biomechanics and histology. µCT demonstrated similar values in the cefuroxime and control group (e.g., callus volume: 67.19 ± 14.90 mm3 vs. 55.35 ± 6.74 mm3, p = 0.12; density: 635.48 ± 14.81 mg HA/cm3 vs. 647.87 ± 13.01 mg HA/cm3, p = 0.16). Biomechanically, similar values were again determined between the groups, in terms of both maximum load (77.65 ± 41.82 vs. 78.54 ± 20.52, p = 0.95) and stiffness (122.44 ± 81.16 vs. 123.74 ± 60.08, p = 0.97). Histological findings were consistent with the radiographic results. Thus, no relevant differences between the cefuroxime and control groups could be found and the reported negative effects on osteoblasts in vitro were not confirmed in vivo by using standard concentrations of cefuroxime. In conclusion, cefuroxime can reasonably be recommended in a clinical setting as an antibiotic therapy when fracture healing is involved. However, supraphysiological doses were not evaluated, which may be present when cefuroxime is used as an additive to bone cement and released over time. Therefore, future studies should evaluate the in vivo effects of prolonged high cefuroxime doses on implant incorporation. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 2282–2291, 2017.
Synthesis and structure of a new trinuclear nickel(II) complex bridged by N‐[3‐(Dimethylamino)propyl]‐N′‐(2‐hydroxyphenyl)oxamido: in vitro anticancer activities, and reactivities toward DNA and protein
Authors: Wang Ju‐Ju , Wang Ling‐Yang , Zheng Kang , Li Yan‐Tuan , Yan Cui‐Wei , Wu Zhi‐Yong 
Published: July 2016

AbstractA new trinickel(II) complex bridged by N‐[3‐(dimethylamino)propyl]‐ N′‐(2‐hydroxylphenyl)oxamido (H3pdmapo), namely [Ni3(pdmapo)2(H2O)2]⋅4CH3OH, was synthesized and characterized by X‐ray single‐crystal diffraction and other methods. In the molecule, two symmetric cis‐pdmapo3− mononickel(II) complexes as a “complex ligand” using the carbonyl oxygen atoms coordinate to the center nickel(II) ion situated on an inversion point. The Ni···Ni distance through the oxamido bridge is 5.2624(4) Å. The center nickel(II) ion and the lateral ones have octahedral and square‐planar coordination geometries, respectively. In the crystal, a three‐dimensional supramolecular network dominated by hydrogen bonds is observed. The reactivity toward DNA/protein bovine serum albumin (BSA) revealed that the complex could interact with herring sperm DNA (HS‐DNA) through the intercalation mode and quench the intrinsic fluorescence of BSA via a static mechanism. The in vitro anticancer activities suggested that the complex is active against the selected tumor cell lines.
Factors influencing pharmacy students’ internship site choice
Authors: Leversha Anne , Stewart Kay 
Published: July 2016

AbstractBackgroundExperiential placements are an essential component of undergraduate pharmacy education in Australia. However, the influence the placements have on students’ choice of intern site warrants further investigation.AimThe aim of this study is to identify factors that influence Monash pharmacy students’ choice of site for their intern training.MethodTwo questionnaires relating to the practical experience placements (PEPs) were completed by students during their final year of undergraduate study. The first questionnaire was conducted prior to hospital pharmacy selection and the second one after that selection process.ResultsAlmost two‐thirds of respondents stated that the expectation of a good internship experience was their reason for choosing their site. Having previous or ongoing employment at the chosen site was also influential. About three‐quarters listed being close to home or university (the site of the training seminars) as a reason for choosing the location of their site.ConclusionOverall, PEPs have a strong influence on the students’ intern site preferences, with metropolitan hospital placements being the major influence.
White LEDs using the sharp β‐sialon: Eu phosphor and Mn‐doped red phosphor for wide‐color gamut display applications
Authors: Yoshimura Kenichi , Fukunaga Hiroshi , Izumi Makoto , Masuda Masatsugu , Uemura Toyonori , Takahashi Kohsei , Xie Rong‐Jun , Hirosaki Naoto 
Published: July 2016

AbstractThe sharp β‐sialon (Si6‐zAlzOzN8‐z : 0 < z < 0.1):Eu green phosphor, combining with a blue LED and CaAlSiN3:Eu red phosphor, is suitable for the wide‐color gamut white LEDs backlighting system, because of its sharp and asymmetric emission spectrum shape. However, the color gamut and the brightness of the aforementioned display is restricted because of the wide emission band of the CaAlSiN3:Eu red phosphor. In this work, we used K2SiF6:Mn as an alternate red phosphor, which has a sharp emission spectrum. The display with the white LED using sharp β‐sialon:Eu and K2SiF6:Mn shows a wide‐color gamut, which covers the hole NTSC triangle. The use of K2SiF6:Mn enables to realize not only a wider color gamut but also a higher brightness of displays, compared with the use of CaAlSiN3:Eu. Furthermore, it is confirmed that the white LED using sharp β‐sialon:Eu and K2SiF6:Mn is stable against temperature and also durable under the accelerated drive conditions.
Short‐stay hospital admission after free tissue transfer for head and neck reconstruction
Authors: Devine Conor M. , Haffey Timothy M. , Trosman Samuel , Fritz Michael A. 
Published: July 2016

Objectives/HypothesisTo show that, for patients with few medical comorbidities and at low risk for airway compromise or fistula formation, early discharge after free tissue transfer for head and neck reconstruction is a safe and viable option.Study DesignRetrospective chart review.MethodsA cohort of patients who underwent free tissue transfer for head and neck reconstruction between February 2010 and December 2014 and who were discharged from the hospital by postoperative day 3 were reviewed.ResultsFifty patients undergoing 51 free‐tissue transfer surgeries were discharged by postoperative day 3. The surgeries performed included anterolateral thigh free flaps (ALT) (n = 46), radial forearm free flaps (n = 2), latissimus myogenous and myocutaneous free flaps (n = 1), supraclavicular free flap (n = 1), and serratus free flap (n = 1). All ALT flaps were harvested exclusively as perforator free flaps; and the vast majority used superficial temporal, angular, or facial vessels. All free flaps were viable without evidence of vascular compromise at discharge and the initial follow‐up appointment.One patient required take‐back for successful flap salvage. One patient experienced late flap failure (between 2–3 weeks postoperatively), requiring another surgery. This resulted in an overall success rate of 98% in this cohort. No other postoperative complications related to early discharge were identified.ConclusionIn a carefully selected subset of patients undergoing free tissue transfer, early discharge has been shown to be possible without compromising patient safety or surgery success rates.Level of Evidence4. Laryngoscope, 126:2679–2683, 2016
Permittivity and loss characteristics of SU8‐quartz composite photoresist at THz frequencies
Authors: Kim Jung‐Mu , Llamas‐Garro Ignacio , Espinosa‐Espinosa Moisés I. , Ke Maolong , Lancaster Michael , de Melo Marcos T. 
Published: July 2016

ABSTRACTAn SU8‐quartz composite photoresist has been fabricated and characterized from 1.2 to 1.4 THz; the material contains quartz particles from 0 to 50 wt%. The composite can reduce the inherent losses of SU8 photoresist at terahertz frequencies. Calculated and measured data is presented and compared with SU8 without quartz inclusions. The results show a reduction in losses and an increase in permittivity in the composite material as the density of quartz particles increases. This initial experiment proves the possibility of modifying the electrical parameters of SU8; increasing the quartz density of the composite will modify these parameters further at THz frequencies. © 2016 Wiley Periodicals, Inc. Microwave Opt Technol Lett 58:2329–2330, 2016