bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives and Experiences Related to Help-Seeking Behaviors: A Content Analysis Study of Iranian Patients With Multiple Sclerosis
Authors: Rabiei Leili , Abedi HeidarAli , Abedi Parvin , Zarea Kourosh , Masoudi Reza 
Published: April 2017

ABSTRACT

Background:
Patients with multiple sclerosis practice help-seeking behaviors largely because of the progression of this physically exhausting disease, which has far reaching psychosocial consequences and requires hospitalization during severe disease exacerbations.

Purpose:
The aim of this study was to describe the perspectives and experiences of Iranian patients with multiple sclerosis regarding help-seeking behaviors.

Methods:
A qualitative design, based on the content analysis approach, was used. Data were drawn from unstructured interviews that were held with 23 participants, who were referred from two teaching hospitals and from the Multiple Sclerosis Society in Ahvaz, Iran.

Results:
During the data analysis, four main themes emerged, including “reliance on God and recourse to the imams,” “striving to gain caring knowledge,” “a need for comprehensive support,” and “attention to spiritual care.”

Conclusions/Implications for Practice:
Healthcare team members, especially nurses, should pay attention to perspectives of patients with multiple sclerosis and try to address these patients’ help-seeking behaviors to provide high-quality care.
The authors hope that the findings of this study will inform the construction of interventional strategies to improve nursing care and facilitate the provision of better support services for people with MS.
Exploring the suitability and acceptability of peer support for older veterans
Authors: Burnell Karen , Needs Adrian , Gordon Kim 
Published: April 2017

Purpose
Informal social support is often sought by veterans to support reminiscence or cope with traumatic memories. However, it can also encourage unhelpful ways of coping, such as avoidance, or may be absent altogether. This project is borrowed from the growing peer support literature. The purpose of this paper is to explore the suitability of peer support services to enhance the wellbeing for older veterans, when naturally occurring support is absent or unhelpful.

Design/methodology/approach
This was a sequentially staged research programme involving a scoping review of current practice and evidence, and a consultation with veterans. In total, ten veterans (nine male, one female) took part in the consultation (M=66 years).

Findings
Peer support was considered suitable, particularly in addressing loneliness and social isolation. There was an understandable concern regarding its use with more complex issues such as trauma. An added issue was the implicit assumption that this consultation concerned transition; supporting younger veteran as they move from military to civilian life. This mirrored the focus of current UK policy and affected the focus of the consultation. Issues were also raised around the sustainability of services more broadly.

Social implications
Peer support is appropriate in supporting older veterans, but must be implemented in a sustainable way. Raising awareness of the needs of older veterans in older adult services is an important implication for service development and delivery.

Originality/value
There is a considerable lack of research concerning older veterans, particularly concerning their formal and informal social support needs. This paper addresses the current gap in the literature.
Water vapor concentration measurements using TDALS with wavelength modulation spectroscopy at varying pressures
Authors: Wei Wei , Chang Jun , Huang Qingjie , Wang Qiang , Liu Yuanyuan , Qin Zengguang 
Published: April 2017

Purpose
As measurement results of optical gas sensors are constantly affected by the pressure of a target gas, approaches must be taken to modify the results. The purpose of this paper is to compare the traditional measurement method with the new measurement system. At the same time, measurement results of the two systems under different pressures are presented for comparison of the detection performance.

Design/methodology/approach
A theoretical model of line shape function and its impact on the measured results is presented, which is based on direct absorption and wavelength modulation spectroscopy (WMS) for gas concentration detection under different pressures. Methods of linear fitting and result modification have been illustrated and compared. A new testing system with the result modification method used for water vapor concentration detection under different pressures between 1 and 7 atm is applied. With an additional pressure sensor placed in the gas cell and calibration performed, relationships between the amplitude of the second harmonic and concentration of the target gas under different pressures can be obtained.

Findings
Amplitude detection can be used for concentration detection regardless of the change in pressure for the method of direct absorption. Although, WMS with second harmonic detection is not enough. Two methods are presented and compared with WMS under different pressures. Moreover, the result modification method shows better performance as computation is significantly reduced.

Originality/value
The comparison between linear fitting and the result modification method with WMS under different pressures is firstly presented. At the same time, a new testing system with better performance for water vapor concentration detection under different pressures is presented as well.
Lean production and the well‐being of the frontline manager: the job demands – resources model as a diagnostic tool in Chinese manufacturing
Authors: Huo Meng‐Long , Boxall Peter 
Published: April 2017

Frontline managers (FLMs) are critical to the implementation of lean production yet its effect on their well‐being is a neglected subject. Illustrating the value of the job demands – resources model as a diagnostic tool, this study examines the impact of lean production on FLM well‐being in a Chinese manufacturer. Following qualitative interviews, survey responses from 226 FLMs were analysed through structural equation modelling. The analysis demonstrated the impact of relevant training, top management support and the level of pay as valuable resources for Chinese FLMs, stimulating their work engagement in a lean context. On the other hand, role overload showed a strong relationship with exhaustion. While perceptions of distributive justice can, to some extent, ameliorate feelings of exhaustion, other resources will most likely need to be mobilised to address the threat to the health of FLMs posed by high levels of work pressure.
Relationship between parent knowledge of child sleep, and child sleep practices and problems: A pilot study in a children's hospital cohort
Authors: McDowall Philippa S , Elder Dawn E , Campbell Angela J 
Published: April 2017

AimTo describe parent reports of sleep practices, and examine associations with parent knowledge of child sleep, and whether children's sleep practices differ between parents who underestimated, overestimated or accurately estimated children's sleep needs.MethodsParents of children aged 2–12 years (n = 115) attending hospital inpatient or day wards were approached and asked to report child sleep routines, sleep problems, parent education, household income and parent knowledge of child sleep via questionnaire.ResultsYounger age was associated with earlier bedtimes and wake times, shorter sleep latencies, longer sleep durations and greater sleep problems (P < 0.05). Parents from higher income homes reported earlier bedtimes and wake times, shorter sleep latencies and fewer sleep problems (P < 0.05). Parents with higher education reported shorter sleep latencies (P < 0.05). Parents with greater knowledge about child sleep reported earlier weekday and weekend bedtimes (r
s ≥ 0.26) and wake times (r
s ≥ 0.21) and greater consistency between their child's weekend and weekday sleep routines (P < 0.05). In comparison with parents who correctly estimated their child's sleep needs: parents who underestimated reported later weekday bedtimes (on average, 46 min), and longer sleep latencies (17 min); parents who overestimated reported longer sleep latencies (22 min). These findings remained significant when controlling for child age (P < 0.05).ConclusionParents with increased sleep knowledge, higher incomes and higher levels of education were more likely to report earlier bedtimes, wake times and more consistent sleep routines for their children.
Improvements in Colorectal Cancer Incidence Not Experienced by Nonmetropolitan Women: A Population‐Based Study From Utah
Authors: Fowler Brynn , Samadder N. Jewel , Kepka Deanna , Ding Qian , Pappas Lisa , Kirchhoff Anne C. 
Published: April 2017

AbstractPurposeLittle is known about disparities in colorectal cancer (CRC) incidence and mortality by community‐level factors such as metropolitan status.MethodsThis analysis utilized data from the Surveillance, Epidemiology, and End Results (SEER) program from Utah. We included patients diagnosed with CRC from 1991 to 2010. To determine whether associations existed between metropolitan/nonmetropolitan county of residence and CRC incidence, Poisson regression models were used. CRC mortality was assessed using multivariable Cox regression models.FindingsCRC incidence rates did not differ between metropolitan and nonmetropolitan counties by gender (males: 46.2 per 100,000 vs 45.1 per 100,000, P = .87; females: 34.4 per 100,000 vs 36.1 per 100,000, P = .70). However, CRC incidence between the years of 2006 and 2010 in nonmetropolitan counties was significantly higher in females (metropolitan: 30.4 vs nonmetropolitan: 37.0 per 100,000, P = .002). As compared to metropolitan counties, the incidence of unstaged CRC in nonmetropolitan counties was significantly higher in both males (1.7 vs 2.8 per 100,000, P = .003) and females (1.4 vs 1.6 per 100,000, P = .002). Among patients who were diagnosed between 2006 and 2010, metropolitan counties were found to have significantly increased survival among males and females, but nonmetropolitan counties showed increased survival only for males.ConclusionsWhile we observed a decreasing incidence of CRC among men and women in Utah, this effect was not seen in women in nonmetropolitan areas nor among those with unstaged disease. Further studies should evaluate factors that may account for these differences. This analysis can inform interventions with a focus on women in nonmetropolitan areas.
Educational and career goal attainments in young adult childhood cancer survivors
Authors: Bashore Lisa , Breyer Emma 
Published: April 2017

AbstractPurposeExamine the educational and career outcomes of young adult childhood cancer survivors.Design and MethodsDescriptive study design using a survey sent to 336 survivors. Quantitative and qualitative data were analyzed separately.ResultsOnly 50 completed surveys were returned. Having a central nervous system tumor and radiation were associated with physical impairments. Four themes also emerged: future as medical professionals, dreams fallen short, peer relationships, and positive outlook on life.Practice ImplicationsPediatric nurses caring for survivors should partner with oncology professionals to support survivors to enrich their educational and career opportunities.
Marine Bioluminescence: Measurement by a Classical Light Sensor and Related Foraging Behavior of a Deep Diving Predator
Authors: Vacquié‐Garcia Jade , Mallefet Jérôme , Bailleul Frédéric , Picard Baptiste , Guinet Christophe 
Published: April 2017

AbstractBioluminescence is produced by a broad range of organisms for defense, predation or communication purposes. Southern elephant seal (SES) vision is adapted to low‐intensity light with a peak sensitivity, matching the wavelength emitted by myctophid species, one of the main preys of female SES. A total of 11 satellite‐tracked female SESs were equipped with a time‐depth‐light 3D accelerometer (TDR10‐X) to assess whether bioluminescence could be used by SESs to locate their prey. Firstly, we demonstrated experimentally that the TDR10‐X light sensor was sensitive enough to detect natural bioluminescence; however, we highlighted a low‐distance detection of the sensor. Then, we linked the number of prey capture attempts (PCAs), assessed from accelerometer data, with the number of detected bioluminescence events. PCA was positively related to bioluminescence, which provides strong support that bioluminescence is involved in predator–prey interactions for these species. However, the limitations of the sensor did not allow us to discern whether bioluminescence (i) provided remote indication of the biological richness of the area to SES, (ii) was emitted as a mechanic reaction or (iii) was emitted as a defense mechanism in response to SES behavior.
Disruption of MDA5-Mediated Innate Immune Responses by the 3C Proteins of Coxsackievirus A16, Coxsackievirus A6, and Enterovirus D68
Authors: Rui Yajuan , Su Jiaming , Wang Hong , Chang Junliang , Wang Shaohua , Zheng Wenwen , Cai Yong , Wei Wei , Gordy James T. , Markham Richard , Kong Wei , Zhang Wenyan , Yu Xiao-Fang 
Published: April 2017

ABSTRACT

Coxsackievirus A16 (CV-A16), CV-A6, and enterovirus D68 (EV-D68) belong to the
Picornaviridae
family and are major causes of hand, foot, and mouth disease (HFMD) and pediatric respiratory disease worldwide. The biological characteristics of these viruses, especially their interplay with the host innate immune system, have not been well investigated. In this study, we discovered that the 3C
pro
proteins from CV-A16, CV-A6, and EV-D68 bind melanoma differentiation-associated gene 5 (MDA5) and inhibit its interaction with MAVS. Consequently, MDA5-triggered type I interferon (IFN) signaling in the retinoic acid-inducible gene I-like receptor (RLR) pathway was blocked by the CV-A16, CV-A6, and EV-D68 3C
pro
proteins. Furthermore, the CV-A16, CV-A6, and EV-D68 3C
pro
proteins all cleave transforming growth factor β-activated kinase 1 (TAK1), resulting in the inhibition of NF-κB activation, a host response also critical for Toll-like receptor (TLR)-mediated signaling. Thus, our data demonstrate that circulating HFMD-associated CV-A16 and CV-A6, as well as severe respiratory disease-associated EV-D68, have developed novel mechanisms to subvert host innate immune responses by targeting key factors in the RLR and TLR pathways. Blocking the ability of 3C
pro
proteins from diverse enteroviruses and coxsackieviruses to interfere with type I IFN induction should restore IFN antiviral function, offering a potential novel antiviral strategy.

IMPORTANCE
CV-A16, CV-A6, and EV-D68 are emerging pathogens associated with hand, foot, and mouth disease and pediatric respiratory disease worldwide. The pathogenic mechanisms of these viruses are largely unknown. Here we demonstrate that the CV-A16, CV-A6, and EV-D68 3C
pro
proteins block MDA5-triggered type I IFN induction. The 3C
pro
proteins of these viruses bind MDA5 and inhibit its interaction with MAVS. In addition, the CV-A16, CV-A6, and EV-D68 3C
pro
proteins cleave TAK1 to inhibit the NF-κB response. Thus, our data demonstrate that circulating HFMD-associated CV-A16 and CV-A6, as well as severe respiratory disease-associated EV-D68, have developed a mechanism to subvert host innate immune responses by simultaneously targeting key factors in the RLR and TLR pathways. These findings indicate the potential merit of targeting the CV-A16, CV-A6, and EV-D68 3C
pro
proteins as an antiviral strategy.
Whole-Exome Sequencing of Metaplastic Breast Carcinoma Indicates Monoclonality with Associated Ductal Carcinoma Component
Authors: Avigdor Bracha Erlanger , Beierl Katie , Gocke Christopher D. , Zabransky Daniel J. , Cravero Karen , Kyker-Snowman Kelly , Button Berry , Chu David , Croessmann Sarah , Cochran Rory L. , Connolly Roisin M. , Park Ben H. , Wheelan Sarah J. , Cimino-Mathews Ashley 
Published: April 2017

Abstract
Purpose: Although most human cancers display a single histology, there are unusual cases where two or more distinct tissue types present within a primary tumor. One such example is metaplastic breast carcinoma, a rare but aggressive cancer with a heterogeneous histology, including squamous, chondroid, and spindle cells. Metaplastic carcinomas often contain an admixed conventional ductal invasive or in situ mammary carcinoma component, and are typically triple-negative for estrogen receptor, progesterone receptor, and HER-2 amplification/overexpression. An unanswered question is the origin of metaplastic breast cancers. While they may arise independently from their ductal components, their close juxtaposition favors a model that postulates a shared origin, either as two derivatives from the same primary cancer or one histology as an outgrowth of the other. Understanding the mechanism of development of these tumors may inform clinical decisions.
Experimental Design: We performed exome sequencing for paired metaplastic and adjacent conventional invasive ductal carcinomas in 8 patients and created a pipeline to identify somatic variants and predict their functional impact, without having normal tissue. We then determined the genetic relationships between the histologically distinct compartments.
Results: In each case, the tumor components have nearly identical landscapes of somatic mutation, implying that the differing histologies do not derive from genetic clonal divergence.
Conclusions: A shared origin for tumors with differing histologies suggests that epigenetic or noncoding changes may mediate the metaplastic phenotype and that alternative therapeutic approaches, including epigenetic therapies, may be required for metaplastic breast cancers. Clin Cancer Res; 23(16); 4875–84. ©2017 AACR.
Research Article. Relationship Between High Levels of Salivary Cotinine Test and Demographic Characteristics of Pregnant Smokers from Mures County
Authors: Georgescu Ion Mihai , Tarcea Monica , Marginean Claudiu , Ruta Florina , Rus Victoria , Sipos Remus , Abram Zoltan 
Published: April 2017

Abstract
Objectives: To evaluate the relationship between the frequency of self-declared status regarding smoking in a group of pregnant women from Mures county, Romania and the high levels of Salivary Cotinine (SC) like biomarkers. Material and methods: It was conducted a retrospective study among 230 pregnant women presented for prenatal care at 50 General Practitioners cabinets in Mures county, Romania, in 2015. Data were collected with a validated questionnaire which included age, level of education, socioeconomic status and ethnicity, also the self-reported smoking status. The Salivary Cotinine level was evaluated using NicAlert Saliva test kits. Results: Using salivary test we identified a high prevalence of involuntary exposure to cigarette smoke among both non-smokers and those who quit smoking before pregnancy. Also we registered pregnant women that although declared smoking cessation before pregnancy their salivary Cotinine levels were high, almost like to an active smoker, probably because of second-hand exposure or because they didn’t say the truth about their habit. Conclusions: We underline the importance of implementing more efficient community interventions among this vulnerable group in order to reduce the frequency of smoking and sustain quitting.
Morphological re-description of Electrotaenia malapteruri (Cestoda: Proteocephalidae) and Dujardinnascaris malapteruri (Nematoda: Heterocheilidae) infecting the Electric catfish Malapterurus electricus and heavy metal accumulation in host and parasites in relation to water and sediment analysis in Lake Manzala, North Delta, Egypt
Authors: Abdel-Gaber Rewaida , Abdel-Ghaffar Fathy , Abdallah Shazly Mohamed , Morsy Kareem , Al Quraishy Saleh , Mohamed Sanna , Mehlhorn Heinz 
Published: April 2017

AbstractParasites are one of the most serious limiting factors in aquaculture. The Electric catfish
The Guerrilla Literacy Learners Project: Development of Literacies through Informal Learning
Authors: Jůvová Alena 
Published: April 2017

Abstract
Introduction: This paper deals with the options of non-formal education and, partially, a set of literacies developed within informal learning, which an individual should be equipped with in order to succeed in life in the contemporary society. At the beginning, there is a mention to the nature of learning and knowledge of society in the context of lifelong learning.
Purpose: The aim of the paper is to analyse and explain non-formal education in contemporary society of knowledge and, subsequently, to provide examples of its use when developing operational literacy. This literacy can be defined as an individual’s ability to be nimble, proactive, and responsive to various life situations.
Methods: The paper serves as an overview study of the subject. For a literary analysis, the methods of comparison and content analysis were used with examples of good practice at the end.
Conclusions: At the end of the paper, one can find an example of the international project “Guerrilla Literacy Learners” the goal of which is to find innovative strategies for informal learning and to develop a methodology that would support the development of literacy and active knowledge of a foreign language by using modern teaching resources, such as ICT, visually attractive materials and adequate methods - MOOC and blended learning.
Additions to the Diptera Acalyptrata fauna (Anthomyzidae, Stenomicridae, Carnidae, Milichiidae, Heleomyzidae) of the Czech Republic and Slovakia
Authors: Roháček Jindřich , Tkoč Michal , Preisler Jiří 
Published: April 2017

Abstract
Records of five species of Diptera Acalyptrata representing novelties for the faunas of Bohemia or Moravia (Czech Republic) and Slovakia are given with discussion on their significance to the biodiversity knowledge of local faunas and a summary of their biology, distribution and identification with new information obtained from the material examined. Stiphrosoma humerale Roháček & Barber, 2005 (Anthomyzidae) and Stenomicra cogani Irwin, 1982 (Stenomicridae) are new additions to the dipterous fauna of Slovakia. Records of Meoneura alpina Hennig, 1948 (Carnidae) and Milichia speciosa Meigen, 1830 (Milichiidae) are the first from Bohemia and represent new northernmost distribution limits of these species; those of Heleomyza (Anypotacta) setulosa (Czerny, 1924) are the first from Moravia. Macrophotographs of all these species are presented to document the specimens recorded and/or to facilitate identification of these uncommon species. In addition, new records of S. humerale from Russia: E Siberia and of M. speciosa from Greece: Peloponnesse are given.
Autonomy of human mind and personality development
Authors: Niemczyński Adam 
Published: April 2017

Abstract
A psychology of human individual development is proposed which argues against its reduction to the description and control of human behavior or to cognitive psychology in the model of information and communication technology. Instead the author’s earlier conceptualization of the autonomy of human individual development is now elaborated further. The foundational premise to this end rests in Macnamara’s (1999) explication of Brentano’s (1874) notion of intentionality, i.e., referring to something as an object. It reveals the access of the mind to the ideal objects and to the kinds which provide for identity and individuation of the objects of human cognition (Macnamara and Reyes, 1994). It converges with the anti-irrationalism postulate which was put forward by Ajdukiewicz (1934). The reduction of the mind in psychology to something else proves unable to meet the anti-irrationalism postulate, regards perception and cognition to be of one piece, and it excludes intuition and ideals. In contrast to this, the notions of the spontaneous and self-sustainable perception and the self-determined mind open a way for psychology without the reduction of it to anything else. The same route has been taken earlier (Niemczyński, 2007) with a study of personality development from adolescence to the late ages.