bluuebunny/crossref_metadata_2025_split huggingface dataset:
Authors: Muller Maria Candida , Lorenzato Sergio 
Published: August 2017

Estes são os resultados da pesquisa de cunho qualitativo e exploratório - O ensino de Geometria nos anos iniciais do ensino fundamental: percepção de professores dos anos iniciais de Vilhena (Rondônia/Brasil) sobre perímetro e área de figuras planas, desenvolvida nos anos de 2013 a 2015. O objetivo foi investigar a percepção dos docentes e futuros docentes com relação aos conceitos de perímetro e área de figuras planas. Aplicou-se um instrumental com dezessete questões. A análise dos dados revelou as dificuldades de compreensão dos conceitos de área e perímetro, também apontados por autores da área de Educação Matemática em outros estudos. A pesquisa pretendeu propor abordagens significativas para o ensino de área e perímetro através de curso de extensão planejado a partir dos dados obtidos na pesquisa.
Authors: Pacífico Juracy Machado , Muller Maria Candida 
Published: August 2017

Este é o número seis da terceira edição da Revista EDUCA - Revista Multidisciplinar em Educação, que iniciou sua publicação em 2014, com publicação semestral, e tem como missão promover a disseminação dos conhecimentos na área das Ciências da Educação. A EDUCA é um periódico científico vinculado ao Grupo de Pesquisa Multidisciplinar em Educação do Departamento de Ciências da Educação, Núcleo de Ciências Humanas/UNIR e ao Programa de Pós-Graduação em Educação Escolar, Mestrado Profissional, da Universidade Federal de Rondônia (UNIR).
Authors: Pacífico/UNIR Juracy Machado 
Published: August 2017

É com satisfação que apresentamos o número sete da quarta edição da Revista EDUCA - Revista Multidisciplinar em Educação. Com ele inauguramos uma nova fase da revista, que passa agora a ter edições com periodicidade quadrimestral. Neste sétimo número a Revista EDUCA traz resultados de pesquisas que abordam o pensamento e reflexão sobre a prática docente, análises de políticas públicas e artigos que discutem aspectos da educação infantil.
Household and Environmental Risk Factors for Kala-azar: A Case-Control Study in Tertiary Care Hospital of Bangladesh
Authors: Ahammed Afsar , Yusuf Md. Abdullah , Feroz Salahuddin , Selim Shahjada , Bhattacharyya Biswajit , Ahammed Imran , Rahman Md Ridwanur 
Published: August 2017

Background: Visceral Leishmaniasis (VL), commonly known as Kala-azar is a chronic febrile disease occurs widely throughout the world. There are many risk factors which can influence the causation of kala azar in Bangladeshi people.Objective: The aim of the present study is to describe the Sociodemographic, household and environmental risk factors of kala-azar among a case series of Bangladeshi patients. Method: This case control study was carried out at inpatient department of Community Based Medical College Hospital, Mymensingh from July 2010 to June 2011, for a period of 1(one) year. The study samples were clinically and parasitologically confirmed kala-azar cases. The controls were rK 39 strip test negative hospitalized cases admitted for other reason.Results: Univariate analysis showed that nature of wall in the main structure, floor of the house, presence of cracks and crevices in walls, presence of a granary inside houses and presence of bamboo trees near houses, were risk factors for kala-azar. Multivariate analysis showed that Presence of cracks and crevices in walls (OR=3.429, 95%CI=1.037-11.338, P =0.043) and presence of bamboo tree around houses (OR=5.652, 95%CI =1.368-23.347, P =0.017) in rural areas of study region, were significant risk factors for kala-azar.Conclusion: These findings have important practical implications because they suggest that on improving housing and environmental conditions in rural areas, may be particularly effective in reducing the incidence of kala-azar and its transmission of infection by sand fly vectors.Journal of Science Foundation, 2016;14(2):56-61
Art and Advanced Practice Nursing: Evidence Supporting Its Relevance in Graduate Education
Authors: Mokel Melissa J. 
Published: August 2017

Background:
Nurses spend more time with health care consumers than any other health care professional and are the largest, most trusted group of health care providers in the U.S. health care system. At the same time, an increasingly diverse and complex society requires that nurses possess a unique capacity to care for consumers using culturally congruent and ethical approaches to care. This challenges nurse educators to provide learning experiences that teach emotional and affective forms of learning that complement the clinical skills acquired through the student's educational experience.

Method:
This article describes an educational innovation using art pedagogy in a course on ethical issues in advanced practice nursing.

Results:
Learners were able to use art to articulate their ideas about feminism, women's health, and race relations in a nonthreatening and creative venue.

Conclusion:

The findings demonstrate the relevance of this educational innovation in achieving learning outcomes for an underreported group—the graduate-level nurse. [
J Nurs Educ.
2017;56(8):501–504.]
The Tabletop Matrix: Determining Reliability for a Criterion-Referenced Performance Measure
Authors: Evans Cathleen A. , Baumberger-Henry Mary 
Published: August 2017

Background:
Disasters are high-impact events. Tabletop exercises are a historic education strategy used to determine policies, procedures, and strengths and challenges for those involved. A tabletop exercise was designed for students to demonstrate transfer of prior medical–surgical content to a novel context of a hospital patient surge following a disaster. To accompany the tabletop exercise, a tabletop matrix was developed as an instrument to measure students' learning transfer of medical–surgical content.

Method:
A pilot study was conducted with senior baccalaureate nursing students to determine instrument reliability and effectiveness of the tabletop exercise.

Results:
Postpilot interrater reliability was established with medical–surgical experts for the matrix, scenarios, and dispositions. Cronbach's alpha could not be calculated, and rationale is provided. Improvements were made to the instrument's items.

Conclusion:

The tabletop matrix was determined to be a criterion-referenced performance measurement of nursing students' learning transfer of medical–surgical concepts to a novel circumstance using a disaster-scenario tabletop exercise. [
J Nurs Educ.
2017;56(8):509–513.]
Assessing Repeatability of Pupillometric Measurements in the Eyes of Refractive Surgery Candidates Using Infrared Pupillometer
Authors: Salah-Mabed Imène , Saad Alain , Gatinel Damien 
Published: August 2017

PURPOSE:
To assess the repeatability of measuring pupil dynamics using an infrared pupillometer.

METHODS:
A total of 124 eyes of 124 patients scheduled for corneal laser refractive surgery were separated into myopic and hyperopic groups and further subdivided based on high or low levels of astigmatism. Measurements were taken using dynamic pupillometry (Topolyzer Vario; Alcon Laboratories, Inc., Sinking Spring, PA). Main outcome measures were pupil diameter size, the distance between the pupil center and the keratoscopic axis, and the spatial shift of the pupil center. Repeatability of measurements was assessed from test–retest repeatability (2.77 Sw), coefficient of variation, and intraclass correlation coefficient (ICC).

RESULTS:
The 2.77 Sw of all measured parameters was lower than 0.36 and 0.44 mm for myopic and hyperopic eyes, respectively. ICCs of the pupil diameter measurements were higher than 0.963 and 0.926 in myopic and hyperopic eyes, respectively. ICCs of the distance between the pupil center and the corneal vertex along the x-axis were higher than 0.934 and 0.994 in myopic and hyperopic eyes, respectively. Along the y-axis, ICCs of this distance were higher than 0.417 in myopic eyes and higher than 0.504 in hyperopic eyes. The pupil center shift measurement ICCs were lower than 0.482 and 0.526 for myopic and hyperopic eyes, respectively.

CONCLUSIONS:
In all groups, the Topolyzer Vario showed excellent repeatability when measuring pupil dynamic parameters except when measuring pupil center shift and distance between the pupil center and the corneal vertex along the vertical axis.

[
J Refract Surg.
2017;33(8):552–557.]
Results of Intraoperative Manual Cyclotorsion Compensation for Myopic Astigmatism in Patients Undergoing Small Incision Lenticule Extraction (SMILE)
Authors: Ganesh Sri , Brar Sheetal , Pawar Archana 
Published: August 2017

PURPOSE:
To study the safety, efficacy, and outcomes of manual cyclotorsion compensation in small incision lenticule extraction (SMILE) for myopic astigmatism.

METHODS:
Eligible patients with myopia from −1.00 to −10.00 diopters (D) spherical equivalent with a minimum astigmatism of 0.75 D undergoing SMILE were included. Intraoperative cyclotorsion compensation was performed by gently rotating the cone and aligning the 0° to 180° limbal marks with the horizontal axis of the reticule of the right eye piece of the microscope of the femtosecond laser after activating the suction.

RESULTS:

In this study, 81 left eyes from 81 patients were analyzed for vector analysis of astigmatism. The mean cyclotorsion was 5.64° ± 2.55° (range: 2° to 12°). No significant differences were found for surgically induced astigmatism, difference vector, angle of error (AE), correction index, magnitude of error, index of success (IOS), and flattening index between 2 weeks and 3 months postoperatively (
P
> .05). The eyes were categorized into low (≤ 1.50 D, n = 37) and high (> 1.50 D, n = 44) cylinder groups. At 3 months, intergroup analysis showed a comparable correction index of 0.97 for the low and 0.93 for the high cylinder groups, suggesting a slight undercorrection of 3% and 7%, respectively (
P
= .14). However, the AE and IOS were significantly lower in the high compared to the low cylinder group (
P
= .032 and .024 for AE and IOS, respectively), suggesting better alignment of the treatment in the high cylinder group. However, the mean uncorrected distance visual acuity of both groups was comparable (
P
= .21), suggesting good visual outcomes in the low cylinder group despite a less favorable IOS.

CONCLUSIONS:
Manual compensation may be a safe, feasible, and effective approach to refine the results of astigmatism with SMILE, especially in higher degrees of cylinders.

[
J Refract Surg.
2017;33(8):506–512.]
Implantable Collamer Lens in the Management of Pseudophakic Ametropia
Authors: Eissa Sherif A. , Khafagy Mohamed M. , Sidky Mohamed Karim 
Published: August 2017

PURPOSE:
To assess Visian Implantable Collamer Lens (ICL) (STAAR Surgical, Monrovia, CA) implantation in the ciliary sulcus to correct pseudophakic ametropia in patients who are not candidates for a keratorefractive procedure.

METHODS:
The authors performed a prospective non-comparative case series study of 18 patients (age: 48 to 61 years) with refractive surprise after phacoemulsification. Patients underwent implantation of a piggyback collagen copolymer lens: V4C design in 16 myopic eyes and V4B design in 2 hyperopic eyes. The position and vault of the ICLs were documented at all control visits clinically and with Pentacam (Oculus Optikgeräte, Wetzlar, Germany). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction spherical equivalent (MRSE), intraocular pressure (IOP), and endothelial cell count were recorded at baseline and 1 week and 1, 6, 12, and 18 months postoperatively.

RESULTS:

The MRSE improved from −3.08 ± 2.37 diopters (D) preoperatively to −0.44 ± −0.23 D postoperatively, corrected with a mean ICL power of −3.20 ± 2.90 D. The mean UDVA improved from 1.03 ± 0.12 logMAR preoperatively to 0.05 ± 0.06 logMAR postoperatively (
P
= .00), whereas CDVA improved from 0.47 ± 0.03 logMAR preoperatively to −0.006 ± 0.02 logMAR (
P
= .001) postoperatively. None of the cases developed interlenticular opacification throughout the 18-month follow-up. The mean ICL vault measured by Scheimpflug tomography was 451.27 ± 178.5 µm. Acute IOP elevation with anterior uveitis developed in 2 eyes and was controlled by topical steroids and a beta-blocker.

CONCLUSIONS:
Sulcus implantation of the secondary ICL to correct pseudophakic refractive error was safe, predictable, and well tolerated in all studied eyes.

[
J Refract Surg.
2017;33(8):532–537.]
Corneal Biomechanics After Accelerated Cross-linking: Comparison Between 18 and 9 mW/cm
2
Protocols
Authors: Hashemi Hassan , Asgari Soheila , Mehravaran Shiva , Miraftab Mohammad , Ghaffari Reza , Fotouhi Akbar 
Published: August 2017

PURPOSE:

To determine 1-year corneal biomechanical changes after accelerated corneal cross-linking in patients with progressive keratoconus and compare them between 5-minute (18 mW/cm
2
) and 10-minute (9 mW/cm
2
) protocols.

METHODS:
In this non-randomized clinical trial, cases in both groups were examined with the Corneal Visualization Scheimpflug Technology (Corvis ST; Oculus Optikgeräte GmbH, Wetzlar, Germany) at baseline and at 6 and 12 months after treatment. Extracted indices included intraocular pressure (IOP), central corneal thickness (CCT), first and second applanation times, lengths, and velocities (T1, T2, L1, L2, V1, and V2), highest concavity time (HCT), deformation amplitude (DA), peak distance between bending points, and radius of curvature.

RESULTS:

Mean patient age, baseline maximum keratometry, CCT, and IOP were similar between groups. After adjusting for CCT and baseline values with repeated measures analysis of covariance, at 1 year after the procedure, IOP (13.14 ± 1.41 vs 12.12 ± 1.49 mm Hg,
P
= .034) and T1 (6.84 ± 0.20 vs 6.67 ± 0.23 ms,
P
= .036) were higher in the 5-minute group, but T2 (21.31 ± 0.27 vs 21.58 ± 0.28 ms,
P
= .007), HCT (16.06 ± 0.51 vs 16.31 ± 0.48 ms,
P
= .017), and DA (1.03 ± 0.09 vs 1.10 ± 0.08 mm,
P
= .028) were lower. Other inter-group differences were not statistically significant (all
P
> .050). All 1-year changes were independent of cone position (all
P
> .050).

CONCLUSIONS:
At 1 year after cross-linking in cases of mild and moderate keratoconus, corneal biomechanics appeared stable or stronger than baseline with both 5- and 10-minute protocols. However, mild cases who had the 5-minute protocol showed better improvement based on Corvis ST indices.

[
J Refract Surg.
2017;33(8):558–562.]
Effect of prey and pollen on interactions between Typhlodromus bagdasarjani and Phytoseiulus persimilis (Acari: Phytoseiidae) on cucumber (Cucurbitaceae)
Authors: Moghadasi Mona , Allahyari Hossein 
Published: August 2017

AbstractIntraguild predation is a notable factor to proper application of biocontrol agents to reduce pest populations. Intraguild predation was studied between Typhlodromus bagdasarjani Wainstein and Arutunjan (Acari: Phytoseiidae) and Phytoseiulus persimilis Athias-Henriot (Acari: Phytoseiidae) in presence and absence of Tetranychus urticae Koch (Acari: Tetranychidae) as well as pollen. Intraguild predation between two predators was bidirectional. The highest and the lowest predation rates of both predators in absence and presence of T. urticae as well as in the pollen treatments were on heterospecific eggs and deutonymphs, respectively. Typhlodromus bagdasarjani consumed more heterospecific eggs compared with P. persimilis. When pollen was added, predation of T. bagdasarjani significantly reduced on heterospecific eggs and deutonymphs in absence and presence of T. urticae treatments, respectively. However, predation rate of P. persimilis on heterospecific stages was not significantly affected by pollen addition. Oviposition of both predators was higher in presence of T. urticae than in its absence and oviposition of P. persimilis was significantly higher on heterospecific stages than T. bagdasarjani. Pollen addition had a significant effect on increasing the oviposition rate of T. bagdasarjani. Extraguild prey presence had a nonsignificant effect on the consumption rate of intraguild prey by the intraguild predators. However, presence of extraguild prey led to a significant increase in oviposition rate of both predators.
Oxidized Low-Density Lipoprotein Loading of Macrophages Downregulates TLR-Induced Proinflammatory Responses in a Gene-Specific and Temporal Manner through Transcriptional Control
Authors: Jongstra-Bilen Jenny , Zhang Cindy X. , Wisnicki Timothy , Li Mengyi K. , White-Alfred Samantha , Ilaalagan Ragave , Ferri Dario M. , Deonarain Ashley , Wan Mark H. , Hyduk Sharon J. , Cummins Carolyn L. , Cybulsky Myron I. 
Published: August 2017

Abstract
Hypercholesterolemia is a key risk factor for atherosclerosis and leads to the uptake of native and oxidized low-density lipoprotein (oxLDL) by macrophages (Mϕs) and foam cell formation. Inflammatory processes accompany Mϕ foam cell formation in the artery wall, yet the relationship between Mϕ lipid loading and their response to inflammatory stimuli remains elusive. We investigated proinflammatory gene expression in thioglycollate-elicited peritoneal Mϕs, bone marrow–derived Mϕs and dendritic cells, and RAW264.7 cells. Loading with oxLDL did not induce peritoneal Mϕ apoptosis or modulate basal-level expression of proinflammatory genes. Upon stimulation of TLR4, the rapid induction of IFN-β was inhibited in cells loaded with oxLDL, whereas the induction of other proinflammatory genes by TLR4 (LPS), TLR3 (polyriboinosinic-polyribocytidylic acid), TLR2 (Pam3CSK4), and TLR9 (CpG) remained comparable within the first 2 h. Subsequently, the expression of a subset of proinflammatory genes (e.g., IL-1β, IL-6, CCL5) was reduced in oxLDL-loaded cells at the level of transcription. This phenomenon was partially dependent on NF erythroid 2–related factor 2 (NRF2) but not on nuclear liver X receptors α and β (LXRα,β), peroxisome proliferator-activated receptor-γ (PPARγ), and activating transcription factor 3 (ATF3). LPS-induced NF-κB reporter activity and intracellular signaling by NF-κB and MAPK pathways were comparable in oxLDL-loaded Mϕs, yet the binding of p65/RelA (the prototypic NF-κB family member) was reduced at IL-6 and CCL5 promoters. This study revealed that oxLDL loading of Mϕs negatively regulates transcription at late stages of TLR-induced proinflammatory gene expression and implicates epigenetic mechanisms such as histone deacetylase activity.
α3-Deletion Isoform of HLA-A11 Modulates Cytotoxicity of NK Cells: Correlations with HIV-1 Infection of Cells
Authors: Zhang Xi-He , Lian Xiao-Dong , Dai Zheng-Xi , Zheng Hong-Yi , Chen Xin , Zheng Yong-Tang 
Published: August 2017

Abstract
Alternative splicing occurs frequently in many genes, especially those involved in immunity. Unfortunately, the functions of many alternatively spliced molecules from immunologically relevant genes remain unknown. Classical HLA-I molecules are expressed on almost all nucleated cells and play a pivotal role in both innate and adaptive immunity. Although splice variants of HLA-I genes have been reported, the details of their functions have not been reported. In the current study, we determined the characteristics, expression, and function of a novel splice variant of HLA-A11 named HLA-A11svE4. HLA-A11svE4 is located on the cell surface without β2-microglobulin (β2m). Additionally, HLA-A11svE4 forms homodimers as well as heterodimers with HLA-A open conformers, instead of combining with β2m. Moreover, HLA-A11svE4 inhibits the activation of NK cells to protect target cells. Compared with β2m and HLA-A11, the heterodimer of HLA-A11svE4 and HLA-A11 protected target cells from lysis by NK cells more effectively. Furthermore, HLA-AsvE4 expression was upregulated by HIV-1 in vivo and by HSV, CMV, and hepatitis B virus in vitro. In addition, our findings indicated that HLA-A11svE4 molecules were functional in activating CD8+ T cells through Ag presentation. Taken together, these results suggested that HLA-A11svE4 can homodimerize and form a novel heterodimeric complex with HLA-A11 open conformers. Furthermore, the data are consistent with HLA-A11svE4 playing a role in the immune escape of HIV-1.
Reliability and Validity of the Belt-Stabilized Handheld Dynamometer in Hip- and Knee-Strength Tests
Authors: Martins Jaqueline , da Silva Janaina Rodrigues , da Silva; Marcelo Rodrigues Barbosa , Bevilaqua-Grossi Débora 
Published: August 2017

Context:
The belt-stabilized handheld dynamometer (HHD) has been used to assess the strength of knee- and hip-muscle groups. However, few researchers have examined its reliability and validity for assessing the strength of these muscles.

Objective:
To evaluate the intra-examiner reliability of the belt-stabilized HHD and its validity and agreement with the isokinetic dynamometer for assessing the strength of knee- and hip-muscle groups.

Design:
Cross-sectional study.

Setting:
University laboratory.

Patients or Other Participants:
We evaluated 26 healthy participants (13 men, 13 women; age = 23.5 ± 2.8 years, height = 1.7 ± 0.1 m, mass = 68.6 ± 12.4 kg) in 2 sessions using the belt-stabilized HHD and an isokinetic dynamometer for maximum strength of the hip adductors, abductors, flexors, extensors, internal rotators, and external rotators and the knee flexors and extensors.

Main Outcome Measure(s):
We used reliability values provided by the intraclass correlation coefficient (2,3), standard error of measurement (SEM and percentage SEM), and minimal detectable change; correlation values comparing the belt-stabilized HHD and the isokinetic instrument using the Pearson correlation coefficient (r); and the mean difference in values comparing the 2 instruments using the Bland-Altman method.

Results:
The intrarater HHD reliability was excellent for most measurements (range = 0.80–0.96; SEM = 1.3–5.3 kilograms of force or 4.8−18.9 Nm, percentage SEM = 7.0%–22.0%, minimal detectable change = 3.6–18.8 kilograms of force or 13.2−52.4 Nm) and was moderate only for bilateral knee flexion and left hip internal rotation (intraclass correlation coefficient [2,3] = 0.62–0.66 and 0.70, respectively). Correlation with the isokinetic dynamometer was moderate to high (r = 0.60–0.90), but the absolute values did not demonstrate concordance between results using the Bland-Altman method.

Conclusions:
The belt-stabilized HHD measurements were reliable, and although they did not agree with those from the isokinetic dynamometer, the values were correlated for the hip- and knee-muscle groups.