bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress, sex, and the enteric nervous system
Authors: Million M. , Larauche M. 
Published: August 2016

AbstractMade up of millions of enteric neurons and glial cells, the enteric nervous system (ENS) is in a key position to modulate the secretomotor function and visceral pain of the gastrointestinal tract. The early life developmental period, through which most of the ENS development occurs, is highly susceptible to microenvironmental perturbation. Over the past decade, accumulating evidence has shown the impact of stress and early life adversity (ELA) on host gastrointestinal pathophysiology. While most of the focus has been on alterations in brain structure and function, limited experimental work in rodents suggest that the enteric nervous system can also be directly affected, as shown by changes in the number, phenotype, and reactivity of enteric nerves. The work of Medland et al. in the current issue of this journal demonstrates that such alterations also occur in pigs, a larger mammalian species with high translational value to human. This work also highlights a sex‐differential susceptibility of the ENS to the effect of ELA, which could contribute to the higher prevalence of GI disorders in women. In this mini‐review, we will discuss the development and composition of the ENS and related gastrointestinal sensory motor and secretory functions. We will then focus on the influence of stress on the enteric nervous system, with a particular emphasis on neurodevelopmental changes. Finally, we will discuss the influence of sex on those parameters.
Love in the Time of Consequentialism
Authors: Maguire Barry 
Published: August 2016

AbstractThere are several powerful motivations for neutral value‐based deontic theories such as Act Consequentialism. Traditionally, such theories have had great difficulty accounting for partiality towards one's personal relationships and projects. This paper presents a neutral value‐based theory that preserves the motivations for Act Consequentialism while vindicating some crucial intuitions about reasons to be partial. There are two central ideas. The first is that when it comes to working out what you ought to do, your friends’ interests, the needs of your family, the significance of your own projects and ideals, etc. have more weight than the interests and needs of strangers. Your friends’ interests are not (thereby) more neutrally valuable than the interests of others. So there is a difference between the value of an outcome and its deontic significance. The second familiar idea is that reasons are modifiable. Reasons of partiality are reasons the weights of which are a function of the value of the relevant outcome modified by facts about the value of caring about the outcome in question. The resulting principle has various further explanatory advantages; in particular, it accounts for project‐ and relationship‐specific permissions and requirements, both at a time and across time.
Repeated nonanesthetic malignant hyperthermia reactions in a child
Authors: Cummings Theresa , Der Tara , Karsli Cengiz 
Published: August 2016

SummaryA series of life‐threatening nonanesthetic‐related MH reactions in a child was the inspiration for a proactive, novel solution allowing for early prehospital, potentially lifesaving intravenous dantrolene administration. Multidisciplinary collaboration is essential and parent education must be comprehensive and ongoing. This case underlines the importance of considering nonanesthetic MH susceptibility in the child who has a history of unspecified myopathy and who presents with fever and total body stiffness.
Immune‐mediated nephropathies in kidney transplants: recurrent or de novo diseases
Authors: Roberti Isabel , Vyas Shefali 
Published: August 2016

AbstractIMN contribute to ESRD in 13% children with renal transplant (txp). Recurrent or de novo IMN can cause graft dysfunction and/or failure, but the details regarding incidence, therapy, and outcome remain poorly understood. Retrospective single‐center study of all pediatric kidney txp was carried out since 1998. Clinical presentation, pathology, therapy, and graft outcomes of children with recurrent or de novo IMN were reviewed. IMN was the primary etiology of ESRD in 28 of the 149 txp recipients. Eleven children had biopsy‐proven post‐txp IMN—six were recurrent and five had de novo. Presentation varied with changes in SCr and/or proteinuria. Initial therapy included higher doses of steroids, MMF, and tacrolimus. Outcome was excellent with only one late graft loss. Full remission was achieved in all other patients, but some had re‐recurrence of the IMN. Median follow‐up time was 11.8 years. IMN (recurrent or de novo) occurred in 7.4% (11 of 149) of all kidney txp performed at our center. IMN post‐txp was often seen late post‐txp, usually asymptomatic and noted to have relapsing pattern. Early diagnosis and prompt therapy resulted in excellent long‐term outcome in children diagnosed with post‐txp IMN.
Identification of candidate miRNAs and expression profile of yak oocytes before and after in vitro maturation by high‐throughput sequencing
Authors: Xiong XR , Lan DL , Li J , Zi XD , Li MY 
Published: August 2016

ContentsSmall RNA represents several unique non‐coding RNA classes that have important function in a wide range of biological processes including development of germ cells and early embryonic, cell differentiation, cell proliferation and apoptosis in diverse organisms. However, little is known about their expression profiles and effects in yak oocytes maturation and early development. To investigate the function of small RNAs in the maturation process of yak oocyte and early development, two small RNA libraries of oocytes were constructed from germinal vesicle stage (GV) and maturation in vitro to metaphase II‐arrested stage (M II) and then sequenced using small RNA high‐throughput sequencing technology. A total of 9,742,592 and 12,168,523 clean reads were obtained from GV and M II oocytes, respectively. In total, 801 and 1,018 known miRNAs were acquired from GV and M II oocytes, and 75 miRNAs were found to be significantly differentially expressed: 47 miRNAs were upregulated and 28 miRNAs were downregulated in the M II oocytes compared to the GV stage. Among the upregulated miRNAs, miR‐342 has the largest fold change (9.25‐fold). Six highly expressed miRNAs (let‐7i, miR‐10b, miR‐10c, miR‐143, miR‐146b and miR‐148) were validated by real‐time quantitative PCR (RT‐qPCR) and consistent with the sequencing results. Furthermore, the expression patterns of two miRNAs and their potential targets were analysed in different developmental stages of oocytes and early embryos. This study provides the first miRNA profile in the mature process of yak oocyte. Seventy‐five miRNAs are expressed differentially in GV and M II oocytes as well as among different development stages of early embryos, suggesting miRNAs involved in regulating oocyte maturation and early development of yak. These results showed specific miRNAs in yak oocytes had dynamic changes during meiosis. Further functional and mechanistic studies on the miRNAs during meiosis may beneficial to understanding the role of miRNAs on meiotic division.
Selection of red deer spermatozoa with different cryoresistance using density gradients
Authors: García‐Álvarez O , Soler AJ , Maulen Z , Maroto‐Morales A , Iniesta‐Cuerda M , Martín‐Maestro A , Fernández‐Santos MR , Garde JJ 
Published: August 2016

ContentsThe objective of sperm selection media is selecting the best spermatozoa and to remove seminal plasma and diluent for using them in assisted reproductive techniques. It is known that individuals show different cryoresistance in response to the same freezing procedure. Our hypothesis was that the efficacy of selection media could be dissimilar for samples with different sperm quality after thawing. Epididymal sperm samples from mature Iberian red deer were collected and frozen. Males were classified as with high post‐thaw sperm quality when sperm motility (SM) ≥ 70%, or as with low post‐thaw sperm quality when SM ≤ 69%. Samples were centrifuged using the following density gradients (DG): Percoll®, Puresperm® and Bovipure™, and several functional sperm parameters were assessed after sperm selecting and washing. Males classified with high sperm quality had higher post‐thawing values (p > .05) for all parameters evaluated, except for linearity index, than those categorized as low sperm quality. After selection, some sperm characteristics improved (viability, apoptosis and mitochondrial activity) for both groups, showing the males with high sperm quality higher values in all sperm parameters except for kinematic traits and DNA fragmentation index (%DFI), regardless of DG. Bovipure™ yield lower values of sperm motility, viability, apoptosis and mitochondrial activity in relation to Percoll® and Puresperm® considering both quality groups. There was an interaction between the type of DG and sperm quality group for sperm viability (p = .040) and apoptosis (p = .003). Thus, Percoll® selected less live and more apoptotic spermatozoa than Puresperm® and Bovipure™ for males with low sperm quality. In conclusion, the DG are more efficient selecting spermatozoa from samples with high sperm quality, acting differently depending on initial sperm quality.
Dependence Evolution in the Spanish Disabled Population: A Functional data Analysis Approach
Authors: Albarrán-Lozano Irene , Alonso-González Pablo J. , Arribas-Gil Ana 
Published: August 2016

SummaryIn a health context, dependence is defined as a lack of autonomy in performing the basic activities of daily living and requiring care giving or significant help from another person. However, this contingency, if present, changes over one's lifetime. Empirical evidence shows that, once this situation occurs, it is almost impossible to return to the previous state and in most cases increases in intensity. In the paper, the evolution of the intensity of this situation is studied for the Spanish population affected by this contingency. Evolution in dependence can be seen as sparsely observed functional data, where we obtain a curve for each individual that is observed at only those points where changes in his or her condition of dependence occur. We use functional data analysis techniques, such as curve registration, functional data depth and distance-based clustering, to analyse this type of data. This approach proves to be useful in this context because it considers the dynamics of the dependence process and provides more meaningful conclusions than simple pointwise or multivariate analysis. We use the sample statistics obtained to predict the future evolution of dependence. The database analysed originates from the ‘Survey on disability, personal autonomy and dependence situations’ in Spain in 2008. The survey is the largest and most complete survey to be made available in Europe for the study of disability. In addition, the Spanish legislation is one of the most recent in Europe and provides a detailed quantitative scale to assess dependence. In the paper, the scale value according to this legislation has been calculated for each individual included in the survey. Differences between sex, age and the time of first appearance were considered, and a prediction of the future evolution of dependence is obtained.
JKL-ECM: an implementation of ECM using Hessian curves
Authors: Heer Henriette , McGuire Gary , Robinson Oisín 
Published: August 2016

We present JKL-ECM, an implementation of the elliptic curve method of integer factorization which uses certain twisted Hessian curves in a family studied by Jeon, Kim and Lee. This implementation takes advantage of torsion subgroup injection for families of elliptic curves over a quartic number field, in addition to the ‘small parameter’ speedup. We produced thousands of curves with torsion$\mathbb{Z}/6\mathbb{Z}\oplus \mathbb{Z}/6\mathbb{Z}$and small parameters in twisted Hessian form, which admit curve arithmetic that is ‘almost’ as fast as that of twisted Edwards form. This allows JKL-ECM to compete with GMP-ECM for finding large prime factors. Also, JKL-ECM, based on GMP, accepts integers of arbitrary size. We classify the torsion subgroups of Hessian curves over$\mathbb{Q}$and further examine torsion properties of the curves described by Jeon, Kim and Lee. In addition, the high-performance curves with torsion$\mathbb{Z}/2\mathbb{Z}\oplus \mathbb{Z}/8\mathbb{Z}$of Bernsteinet al. are completely recovered by the$\mathbb{Z}/4\mathbb{Z}\oplus \mathbb{Z}/8\mathbb{Z}$family of Jeon, Kim and Lee, and hundreds more curves are produced besides, all with small parameters and base points.
Tuple lattice sieving
Authors: Bai Shi , Laarhoven Thijs , Stehlé Damien 
Published: August 2016

Lattice sieving is asymptotically the fastest approach for solving the shortest vector problem (SVP) on Euclidean lattices. All known sieving algorithms for solving the SVP require space which (heuristically) grows as$2^{0.2075n+o(n)}$, where$n$is the lattice dimension. In high dimensions, the memory requirement becomes a limiting factor for running these algorithms, making them uncompetitive with enumeration algorithms, despite their superior asymptotic time complexity.We generalize sieving algorithms to solve SVP with less memory. We consider reductions of tuples of vectors rather than pairs of vectors as existing sieve algorithms do. For triples, we estimate that the space requirement scales as$2^{0.1887n+o(n)}$. The naive algorithm for this triple sieve runs in time$2^{0.5661n+o(n)}$. With appropriate filtering of pairs, we reduce the time complexity to$2^{0.4812n+o(n)}$while keeping the same space complexity. We further analyze the effects of using larger tuples for reduction, and conjecture how this provides a continuous trade-off between the memory-intensive sieving and the asymptotically slower enumeration.
Computing theta functions in quasi-linear time in genus two and above
Authors: Labrande Hugo , Thomé Emmanuel 
Published: August 2016

We outline an algorithm to compute $\unicode[STIX]{x1D703}(z,\unicode[STIX]{x1D70F})$ in genus two in quasi-linear time, borrowing ideas from the algorithm for theta constants and the one for $\unicode[STIX]{x1D703}(z,\unicode[STIX]{x1D70F})$ in genus one. Our implementation shows a large speed-up for precisions as low as a few thousand decimal digits. We also lay out a strategy to generalize this algorithm to genus $g$.
Roots of sparse polynomials over a finite field
Authors: Kelley Zander 
Published: August 2016

For a$t$-nomial$f(x)=\sum _{i=1}^{t}c_{i}x^{a_{i}}\in \mathbb{F}_{q}[x]$, we show that the number of distinct, nonzero roots of$f$is bounded above by$2(q-1)^{1-\unicode[STIX]{x1D700}}C^{\unicode[STIX]{x1D700}}$, where$\unicode[STIX]{x1D700}=1/(t-1)$and$C$is the size of the largest coset in$\mathbb{F}_{q}^{\ast }$on which$f$vanishes completely. Additionally, we describe a number-theoretic parameter depending only on$q$and the exponents$a_{i}$which provides a general and easily computable upper bound for $C$. We thus obtain a strict improvement over an earlier bound of Canettiet al. which is related to the uniformity of the Diffie–Hellman distribution. Finally, we conjecture that$t$-nomials over prime fields have only$O(t\log p)$roots in$\mathbb{F}_{p}^{\ast }$when$C=1$.
Explicit isogenies in quadratic time in any characteristic
Authors: De Feo Luca , Hugounenq Cyril , Plût Jérôme , Schost Éric 
Published: August 2016

Consider two ordinary elliptic curves$E,E^{\prime }$defined over a finite field$\mathbb{F}_{q}$, and suppose that there exists an isogeny$\unicode[STIX]{x1D713}$between$E$and$E^{\prime }$. We propose an algorithm that determines$\unicode[STIX]{x1D713}$from the knowledge of$E$,$E^{\prime }$and of its degree$r$, by using the structure of the$\ell$-torsion of the curves (where $\ell$ is a prime different from the characteristic $p$of the base field). Our approach is inspired by a previous algorithm due to Couveignes, which involved computations using the$p$-torsion on the curves. The most refined version of that algorithm, due to De Feo, has a complexity of $\tilde{O} (r^{2})p^{O(1)}$base field operations. On the other hand, the cost of our algorithm is$\tilde{O} (r^{2})\log (q)^{O(1)}$, for a large class of inputs; this makes it an interesting alternative for the medium- and large-characteristic cases.
Complete Genome Sequence of Foot-and-Mouth Disease Virus Serotype SAT3 Zimbabwe/4/81
Authors: You Su-Hwa , Pyo Hyun Mi , Lee Seo-Yong , Ko Mi-Kyeong , Choi Joo-Hyung , Shin Sung Ho , Lee Kwang-Nyeong , Kim Byounghan , Park Jong-Hyeon 
Published: August 2016

ABSTRACT
The complete genome sequence of a foot-and-mouth disease (FMD) serotype SAT3 virus ZIM/4/81, which belongs to a topotype 1 (SEZ), is reported here.
Draft Genome Sequence of
Lactobacillus reuteri
Strain CRL 1098, an Interesting Candidate for Functional Food Development
Authors: Torres Andrea C. , Suárez Nadia E. , Font Graciela , Saavedra Lucila , Taranto María Pía 
Published: August 2016

ABSTRACT

We report here the draft genome sequence of
Lactobacillus reuteri
strain CRL 1098. This strain represents an interesting candidate for functional food development because of its proven probiotic properties. The draft genome sequence is composed of 1,969,471 bp assembled into 45 contigs and an average G+C content of 38.8%.
Complete Genome Sequence of
Neisseria weaveri
Strain NCTC13585
Authors: Alexander Sarah , Fazal Mohammed-Abbas , Burnett Edward , Deheer-Graham Ana , Oliver Karen , Holroyd Nancy , Parkhill Julian , Russell Julie E. 
Published: August 2016

ABSTRACT

Neisseria weaveri
is a commensal organism of the canine oral cavity and an occasional opportunistic human pathogen which is associated with dog bite wounds. Here we report the first complete genomic sequence of the
N. weaveri
NCTC13585 (CCUG30381) strain, which was originally isolated from a patient with a canine bite wound.
Multiple Genome Sequences of the Important Beer-Spoiling Species
Lactobacillus backii
Authors: Geissler Andreas J. , Behr Jürgen , Vogel Rudi F. 
Published: August 2016

ABSTRACT

Lactobacillus backii
is an important beer-spoiling species. Five strains isolated from four different breweries were sequenced using single-molecule real-time sequencing. Five complete genomes were generated, which will help to understand niche adaptation to beer and provide the basis for consecutive analyses.
Draft Genome Sequences of Two
Bacillus anthracis
Strains from Etosha National Park, Namibia
Authors: Valseth Karoline , Nesbø Camilla L. , Easterday W. Ryan , Turner Wendy C. , Olsen Jaran S. , Stenseth Nils C. , Haverkamp Thomas H. A. 
Published: August 2016

ABSTRACT

Bacillus anthracis
strains K1 and K2 were isolated from two plains zebra anthrax carcasses in Etosha National Park, Namibia. These are draft genomes obtained by Illumina MiSeq sequencing of isolates collected from culture of blood-soaked soil from each carcass.
Complete Genome Sequences of the Historical
Legionella pneumophila
Strains OLDA and Pontiac
Authors: Mercante Jeffrey W. , Morrison Shatavia S. , Raphael Brian H. , Winchell Jonas M. 
Published: August 2016

ABSTRACT

Here, we report the complete genome sequences of
Legionella pneumophila
serogroup 1 strains OLDA and Pontiac, which predate the 1976 Philadelphia Legionnaires' disease outbreak. Strain OLDA was isolated in 1947 from an apparent sporadic case, and strain Pontiac caused an explosive outbreak at a Michigan health department in 1968.
Draft Genome Sequences of
Pseudoalteromonas telluritireducens
DSM 16098 and
P. spiralis
DSM 16099 Isolated from the Hydrothermal Vents of the Juan de Fuca Ridge
Authors: Zhang Huan , Liu Rui , Wang Mengqiang , Wang Hao , Gao Qiang , Hou Zhanhui , Zhou Zhi , Gao Dahai , Wang Lingling 
Published: August 2016

ABSTRACT

This report describes the draft genome sequences of two strains,
Pseudoalteromonas telluritireducens
DSM 16098 and
P. spiralis
DSM 16099, which were isolated from hydrothermal vents of the Juan de Fuca Ridge. The reads generated by an Ion Torrent PGM were assembled into contigs with total sizes of 4.4 Mb and 4.1 Mb for DSM 16098 and DSM 16099, respectively.
Draft Genome Sequence of
Alcanivorax
sp. Strain KX64203 Isolated from Deep-Sea Sediments of Iheya North, Okinawa Trough
Authors: Zhang Huan , Liu Rui , Wang Mengqiang , Wang Hao , Gao Qiang , Hou Zhanhui , Gao Dahai , Wang Lingling 
Published: August 2016

ABSTRACT

This report describes the draft genome sequence of
Alcanivorax
sp. strain KX64203, isolated from deep-sea sediment samples. The reads generated by an Ion Torrent PGM were assembled into contigs, with a total size of 4.76 Mb. The data will improve our understanding of the strain's function in alkane degradation.
On the Behaviour, abundance, habitat use and potential threats of the Gangetic Dolphin Platanista gangetica in southern West Bengal, India
Authors: Chowdhury Mahua Roy , Mitra Sangita , Sen Saswati 
Published: August 2016

The Ganga River Dolphin Platanista gangetica Roxburgh, 1801 is a globally endangered cetacean found in the River system of Ganga, Brahmaputra and Meghna in Bangladesh and India. A survey and research were conducted from 2012–2014 to explore the behaviour, abundance, habitat use and potential threats of the Dolphin in the lower, middle and upper stretches of the river Ganga and its tributaries in southern West Bengal. The study recorded different types of surfacing patterns with respect to their age class as well as on diurnal activity pattern of the individual. The adults and sub-adults were found to have different types of surfacing during different hours of the day. The morning and afternoon were observed to be feeding hours of the Dolphin. Multiple potential threats were encountered during the present study such as destructive fishing gears, dumping of solid and municipal waste, industrial effluents, agricultural run-off, construction of water structures, water extraction and reduction of river depth attributed to siltation. These factors contributed to the present study of the river dolphins in the Ganga, which are localised at certain pockets in good number.
Effect of vehicular traffic on wild animals in Sigur Plateau, Tamil Nadu, India
Authors: Samson A. , Ramakrishnan B. , Veeramani A. , Santhoshkumar P. , Karthick S. , Sivasubramanian G. , Ilakkia M. , Chitheena A. , Princy J. Leona , Ravi P. 
Published: August 2016

The construction of a road, directly and indirectly, impacts on the ecosystems where the road is built. Highways passing through national reserves/wildlife sanctuaries have an adverse impact on wild animals. The present survey was conducted to estimate the road kills on the state highways passing through the Nilgiri north territorial forest division (19km) and Mudumalai Tiger Reserve (15km) in Sigur Plateau, Tamil Nadu, India. The road kills were monitored three times a month between July 2013 and December 2013 (six months) and a total of 176 road kills belonging to 30 species were recorded. Reptiles were the most affected taxa (39%), followed by mammals (33%) and birds (21%). Amphibians were least affected by vehicular traffic and comprised 7% of the total kills. According to road stretch category, the overall road kill was N=135 in the forested area and N=41 in human habitations. A total of 812 food materials were encounterd 612km with average of 1.32 food materials / km. Conservation and management implications are essential to prevent the local extinction of wildlife.
Notes on three species of Palaearctic satyrinae (Lepidoptera: Nymphalidae) from northwestern Himalaya, India
Authors: Singh Arun P. 
Published: August 2016

Observations are presented on local abundance, habitat and distribution of three species of lesser known Satyrinae butterflies in India, namely the Oriental Meadowbrown Hyponephele cheena Moore, 1865 from Chamba district in Himachal Pradesh, the Yellow Wall Kirinia eversmanni cashmierensis Moore, 1874 from Handwara, Jammu & Kashmir and the comparison of the Tawny Meadowbrown, Hyponephele pulchella Felder & Felder, 1867 from Gulmarg, Jammu & Kashmir with its congeners (Hyonephele pulchra, H.astorica, H. Baroghila, H.sylvia & H. coenonympha).