bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motion Sensing Superpixels (MOSES): A systematic framework to quantify and discover cellular motion phenotypes
Authors: Zhou Felix Y. , Ruiz-Puig Carlos , Owen Richard P. , White Michael J. , Rittscher Jens , Lu Xin 
Published: January 2018

AbstractCellular motion is fundamental in tissue development and homeostasis. There is strong interest in identifying factors that affect the interactions of cells in disease but analytical tools for robust and sensitive quantification in varying experimental conditions for large extended timelapse acquisitions is limited. We present Motion Sensing Superpixels (MOSES), a method to systematically capture diverse features of cellular dynamics. We quantify dynamic interactions between epithelial cell sheets using cell lines of the squamous and columnar epithelia in human normal esophagus, Barrett’s esophagus and esophageal adenocarcinoma and find unique boundary formation between squamous and columnar cells. MOSES also measured subtle changes in the boundary formation caused by external stimuli. The same conclusions of the 190 videos were arrived at unbiasedly with little prior knowledge using a visual motion map generated from unique MOSES motion ‘signatures’. MOSES is a versatile framework to measure, characterise and phenotype cellular interactions for high-content screens.
Drosophila Toll links systemic immunity to long-term intestinal function
Authors: Atilano Magda L. , Glittenberg Marcus , Bahuguna Shivohum , Wang Lihui , Ligoxygakis Petros 
Published: January 2018

AbstractThe intestine is an organ where immune and metabolic functions are co-ordinated with tissue renewal via progenitor somatic stem cells (PSSCs). How this is achieved is still unclear. We report that in Drosophila, a generalised infection increased PSSC numbers. This was mimicked by expressing a constitutive form of the immune receptor Toll in PSSCs and blocked when Toll was silenced via RNAi. Without infection, absence of bacterial recognition and downstream Toll signalling resulted in a short lifespan and an age-dependent decrease of PSSCs and gut microbiota. The latter implied a metabolic environment incompatible with the presence of bacteria. Indeed, infection or constitutive Toll signalling in PSSCs triggered 4E-BP transcription in enterocytes, while loss of signalling reduced it. 4E-BP controlled fat levels and sustained the microbiota suggesting that Toll-dependent regulation of 4E-BP was important for long-term gut function. Therefore, the Toll pathway is crucial for responses to both infection and microbiota.
Patterns of polymorphism, selection and linkage disequilibrium in the subgenomes of the allopolyploid Arabidopsis kamchatica
Authors: Paape Timothy , Briskine Roman V. , Lischer Heidi E.L , Halstead-Nussloch Gwyneth , Shimizu-Inatsugi Rie , Hatekayama Masaomi , Tanaka Kenta , Nishiyama Tomoaki , Sabirov Renat , Sese Jun , Shimizu Kentaro K. 
Published: January 2018

AbstractAlthough genome duplication is widespread in wild and crop plants, little is known about genome-wide selection due to the complexity of polyploid genomes. In allopolyploid species, the patterns of purifying selection and adaptive substitutions would be affected by masking owing to duplicated genes or ‘homeologs’ as well as by effective population size. We resequenced 25 distribution-wide accessions of the allotetraploid Arabidopsis kamchatica, which has a relatively small genome size (450 Mb) derived from the diploid species A. halleri and A. lyrata. The level of nucleotide polymorphism and linkage disequilibrium decay were comparable to A. thaliana, indicating the feasibility of association studies. A reduction in purifying selection compared with parental species was observed. Interestingly, the proportion of adaptive substitutions (α) was significantly positive in contrast to the majority of plant species. A recurrent pattern observed in both frequency and divergence-based neutrality tests is that the genome-wide distributions of both subgenomes were similar, but the correlation between homeologous pairs was low. This may increase the opportunity of different evolutionary trajectories such as in the HMA4 gene involved in heavy metal hyperaccumulation.
Strong hybrid male incompatibilities impede the spread of a selfish chromosome between populations of a fly
Authors: Verspoor Rudi L. , Smith Jack M. L. , Mannion Natasha L. M. , Hurst Gregory D. D. , Price Tom A. R. 
Published: January 2018

AbstractMeiotically driving sex chromosomes manipulate gametogenesis to increase their transmission at a cost to the rest of the genome. The intragenomic conflicts they produce have major impacts on the ecology and evolution of their host species. However their ecological dynamics remain poorly understood. Simple population genetic models predict meiotic drivers will rapidly reach fixation in a population and spread across a landscape. In contrast, natural populations commonly show spatial variation in the frequency of drivers, with drive present in clines or mosaics across species ranges. For example,Drosophila subobscuraharbours a Sex Ratio distorting drive chromosome (“SRs”) at 15-25% frequency in North Africa, present at less than 2% frequency in adjacent Southern Spain and absent in other European populations. Here, we investigate the forces preventing the spread of the driver northward. We show that SRshas remained at a constant frequency in North Africa, and failed to spread in Spain. We find strong evidence in favour of our first hypothesis, genetic incompatibility between SRs and Spanish autosomal background. When we cross SRsfrom North Africa onto Spanish genetic backgrounds we observe strong SRsspecific incompatibilities in hybrids. The incompatibilities increase in severity in F2 male hybrids, leading to almost complete infertility. We find no evidence supporting a second hypothesis, that there is resistance to drive in Spanish populations. We conclude that the source of the stepped frequency variation is genetic incompatibility between the SRschromosome and the genetic backgrounds of the adjacent population, preventing SRsspreading northward. The low frequency of SRsin South Spain is consistent with recurrent gene flow across the Strait of Gibraltar combined with selection against the SRselement through genetic incompatibility. This demonstrates that incompatibilities between drive chromosomes and naïve populations can prevent the spread of drive between populations, at a continental scale.
A novel representative in the rare family of trivanadates, KMn2V3O10: synthesis, crystal structure and magnetic properties
Authors: Yakubovich Olga , Shvanskaya Larisa , Pchelkina Zlata , Dimitrova Olga , Volkov Anatoliy , Volkova Olga , Vasiliev Alexander 
Published: January 2018

Potassium dimanganese trivanadate, KMn2V3O10, was synthesized hydrothermally and its crystal structure was determined from single-crystal X-ray diffraction data. The novel phase crystallizes with triclinic symmetry in space group P\bar 1 with unit-cell parameters of a = 6.912 (5), b = 6.993 (5), c = 9.656 (5) Å, α = 101.858 (5), β = 102.627 (5), γ = 100.669 (5)°, Z = 2 and V = 432.6 (5) Å3. Its structure is built from tetramers of MnO6 octahedra sharing edges and trimers of VO4 tetrahedra sharing vertices. These main structural fragments are linked in a three-dimensional framework with channels occupied by potassium ions. The transformation of this structure to that of interconnected NaCa3Mn(V3O10)(V2O7) is discussed. The title compound orders antiferromagnetically at T
N = 8.2 K due to the magnetic exchange interactions between tetramers of Mn octahedra through VO4 tetrahedra. First-principles calculations show the magnetic couplings via Mn—O—Mn and Mn—O—V—O—Mn pathways.
Avoidance of sponsored posts on consumer-generated content: a study of personal blogs
Authors: Mutum Dilip S. , Ghazali Ezlika M. , Mohd-Any Amrul Asraf , Nguyen Bang 
Published: January 2018

PurposeThis study aims to conceptualise and empirically examine how blog users engage with the sponsored posts on consumer-generated content, specifically blogs.Design/methodology/approachThis paper empirically tested the proposed hypotheses using the structural equation modelling using a sample of 399 blog users.FindingsThe need for cognition, perceived interactivity and perceived credibility of blogs has been found to directly influence consumers’ attitude towards blogs. Innovativeness has been found to have a weak negative link with the attitude towards blogs. Blog users were more favourable towards the sponsored posts if the blogs were more interactive. Attitude towards blogs has been found to mediate the relationship between users’ perceived interactivity and their avoidance of the sponsored posts and also between perceived credibility and avoidance of the sponsored posts on blogs. The most significant finding of this study is that the positive attitude towards a blog results in a higher avoidance of the sponsored posts.Research limitations/implicationsThis study focuses on the sponsored posts on blogs. It does not look at other forms of advertising on blogs such as banner ads, or other forms of consumer-generated content.Practical implicationsMarketers and bloggers should carefully consider the suitability of the sponsored posts on blogs as they risk alienating the regular users of the blogs. Sponsored posts which are perceived as honest reviews (as opposed to paid advertorials) might be more acceptable to blog users.Social implicationsThis study highlights the importance of credibility of bloggers to blog users. There are some serious ethical issues related to the sponsored posts which have not been discussed here but need to be examined further.Originality/valueThis study represents one of the first attempts to conceptualise and empirically examine how blog users engage with customer-generated advertising – sponsored posts. It contributes to marketing literature by enhancing the understanding of how consumers perceive consumer-generated content and more specifically, with regard to consumer attitudes towards online consumer-generated advertising. This study enhances the theoretical and empirical knowledge on how consumers react to advertisements on social media, with important suggestions for future research and implications for practitioners.
Improving journeys by opening data: the case of Transport for London (TfL)
Authors: Stone Merlin , Aravopoulou Eleni 
Published: January 2018

PurposeThis case study describes how one of the world’s largest public transport operations, Transport for London (TfL), transformed the real-time availability of information for its customers and staff through the open data approach, and what the results of this transformation were. The purpose of this paper is therefore to show what is required for an open data approach to work.Design/methodology/approachThis case study is based mainly on interviews at TfL and data supplied by TfL directly to the researchers. It analyses as far as possible the reported facts of the case to identify the processes required for open data and the benefits thereof.FindingsThe main finding is that achieving an open data approach in public transport is helped by having a clear commitment to the idea that the data belong to the public and that third parties should be allowed to use and repurpose the information, by having a strong digital strategy, and by creating strong partnerships with data management organisations that can support the delivery of high volumes of information.Research limitations/implicationsThis research is based upon a single case study, albeit over an extensive period, so the findings cannot be applied simply to other situations, other than as evidence of what is possible. However, similar processes could be applied in other situations as a heuristic approach to open data strategy implementation.Practical implicationsThe case study shows how open data can be used to create commercial and non-commercial customer-facing products and services, which passengers and other road users use to gain a better travel experience, and that this approach can be valued in terms of financial/economic contribution to customers and organisations.Social implicationsThis case study shows the value that society can obtain from the opening of data in public transport, and the importance of public service innovation in delivering benefits to citizens.Originality/valueThis is the first case study to show in some detail some of the processes and activities required to open data to public service customers and others.
Understanding intercultural dynamics
Authors: Liu Leigh Anne , Adair Wendi L. , Tjosvold Dean , Poliakova Elena 
Published: January 2018

PurposeThe purpose of this paper is to provide an overview on the state of the field in intercultural dynamics on competition and cooperation at the individual, team, and organizational levels. The authors integrate previous studies from multiple disciplines to articulate the contextual importance of intercultural dynamics. The authors also suggest three overarching themes to expand the field of research on intercultural dynamics.Design/methodology/approachThe authors use an integrative literature review to articulate the importance of intercultural dynamics, provide an introduction to the new contributions in this special issue, and propose new directions for future research.FindingsIntercultural dynamics research has the potential to expand in three overarching areas: constructive controversy, collaborative communication, and global competency and identity at multiple levels.Research limitations/implicationsIntercultural dynamics is still a nascent field emerging from cross-cultural and strategic management. The authors hope the review lays the groundwork for more studies on intercultural dynamics at the interpersonal, team, organizational, and mixed levels of analysis in both theory building and empirical works.Practical implicationsUnderstanding intercultural dynamics in competition and cooperation can help individuals and managers in multinationals and born global organizations navigate cultural complexity and foster cooperation.Social implicationsThe authors hope the ideas on intercultural dynamics can facilitate collaboration and reduce conflict in intercultural encounters at the individual, organization, and societal levels.Originality/valueThis paper offers an overview on the state of the field and lays groundwork for more systematic inquiries on intercultural dynamics in competition and cooperation.
Economic development and health improvement: mutual support in the historical UK (1541-2001)
Authors: Dalko Viktoria , Wang Michael H. 
Published: January 2018

PurposeThe purpose of this paper is to study the mutual disruption and support of economic growth and health improvement in the last 500 years in the UK.Design/methodology/approachThe paper is a general review and it compares institutional development, public policy, technological advances and scientific discoveries in economic growth with those in health improvement.FindingsThe paper finds the co-existence of slower economic growth and less increasing life expectancy from 1541 to 1871 and that of faster economic growth and rising life expectancy from 1871 to 2001. It is organized health improvement that effectively propelled economic growth in the time span of 1871-2001.Research limitations/implicationsThe findings may contribute to the literature on mutual enhancement between economic growth and health improvement.Practical implicationsThe findings may also provide implications to the policy makers how important organized health improvement is to economic growth.Social implicationsThe findings show that when UK Government was leading in organized health improvement for the population, economic grown got propelled into a faster lane.Originality/valueThis paper is among the first to unveil that a socially responsible government has permanent impact on the paths of both economic and social growth. It has value to other researchers attempting to understand the mutual disruption and support of economic growth and health improvement in the historical UK.
Converging crime rates among European countries? A note
Authors: Kollias Christos , Leventi Theodosia , Messis Petros 
Published: January 2018

Purpose
Social change and modernization theories postulate that as countries grow they gradually move toward a condition of similarity in various spheres exhibiting similar economic and social traits. The purpose of this paper is to investigate whether a process of convergence in terms of criminality levels is present in the case of European countries.

Design/methodology/approach
The research question at hand is tackled through conventional s and ß-convergence methodologies and a battery of unit root tests in the case of 16 European countries over the period 1972-2012.

Findings
The findings reported, herein, are quite uniform irrespective of the empirical methodology employed to investigate the issue at hand. The result points to a process of convergence in terms of crime rates. However, this convergence process, although present and statistically traceable, is a rather gradual one as this is depicted both by the value of the β-coefficient as well as by the trend of the coefficient of variation.

Originality/value
Most of the studies in this strand of the literature focus on investigating the association between economic conditions such as unemployment and crime or on the effectiveness of crime thwarting policies. To the best of the knowledge, this is the first paper that addresses the issue of convergence in terms of crime rates in the case of European countries.
Social transitions in the Savannah
Authors: Majekodunmi Ayodele O. 
Published: January 2018

PurposeThe purpose of this paper is twofold: first, to explore social risk management strategies amongst Fulani in the subhumid zone of Nigeria; and second, to determine current status and nature of reciprocal exchange networks, risk pooling and social support for pastoral livelihoods in North-Central Nigeria.Design/methodology/approachSurveys of cattle productivity and pastoral livelihoods were carried out amongst Fulani pastoralists on the Jos Plateau: between 2008 and 2013 using participatory epidemiology methods and the sustainable livelihoods framework. Qualitative and quantitative data on livelihood activities, knowledge, attitudes and practices of animal husbandry and disease control, wealth grouping, herd entries and exits was gathered to determine the current state of cattle productivity and pastoral livelihoods in the study area.FindingsResults show that reciprocal exchange networks for risk management have mostly disintegrated and patron-client relationships have become an important social risk management strategy.Practical implicationsThis research has significant implications for sustainability of Fulani livelihoods and communities: decreased social risk-management strategies and increased self-reliance means that the most vulnerable households will find it more difficult to withstand shocks and climb out of poverty. Wealthier households may cope better with high incidence/low severity shocks like but are more vulnerable to low incidence/high severity shocks. Likewise, decreased social cohesion reduces the ability of communities to mobilise and act collectively in the face of community-level shocks. This is very important for engagement with the state – a crucial process, given current levels of acrimony and conflict.Originality/valueGiven the high levels of farmer-herder conflict and civil unrest in this region over the past 15 years this research is valuable in providing insights into economic drivers of conflict, current dynamics of pastoral livelihoods and social cohesion within and between communities.
Parental feeding practice is associated with child’s body mass index in Thai school-aged children
Authors: Yamborisut Uruwan , Visetchart Piyanuch , Thasanasuwan Wiyada , Srichan Weerachat , Unjana Rittirong 
Published: January 2018

Purpose
Parental feeding practice (PFP) plays an important role in child’s eating behavior and weight status, but less information is available about its role in the Thai family setting. The purpose of this paper is to examine the influence of PFP on child’s gender and body mass index (BMI).

Design/methodology/approach
Participants included 227 parents-child dyads from the suburban area of Nakhon Pathom province, Thailand. Children aged 9-12 years and parents who were either child’s mother, father or grandfather/grandmother were enrolled in the study. Body weight, height, waist circumference and body fat were measured in all children. Eating behavior of each child was assessed by using child’s eating questionnaire. Parents also provided their feeding practices in child feeding questionnaires. Information on household food security was also obtained from children’s parents.

Findings
There was significant difference in eating behaviors and home environment between child’s genders. For child’s eating behavior, mean total eating scores of girls were significantly greater (p=0.002) than that of boys and that the inappropriate home environment was more found in families of boys than girls. Regarding feeding practice, parents used more food restriction (p=0.008) and monitoring on child’s eating (p=0.042) in girls than boys. Parents put more pressure to eat on the normal weight than obese children (p=0.001). Regression analysis revealed that, apart from parental BMI and household income, PFPs have a significant impact (15.6 percent explained variance) on child’s BMI.

Originality/value
This study highlights the importance of being aware of child’s gender and weight status when feeding practices were provided to them. Nutrition education for parents should take account for parents’ perceptions and concerns as well as the modification of feeding practices to improve children’s eating behaviors.