bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical Simulation on Cathodic Protection Potential Distribution Along Horizontal Directional Drilling Pipe
Authors: Zhuang Dawei , Du Yanxia , Tang Dezhi , Du Chen 
Published: September 2024

ABSTRACTEvaluating the cathodic protection (CP) effectiveness of horizontal directional drilling (HDD) pipe is a significant technical challenge, due to the feasibility of testing only in shallow buried areas at entry/exit extremities, and not in deeply buried areas or the crossing section of the pipe. Numerical simulation provides a method to evaluate the CP effectiveness of HDD pipes. To improve the accuracy of potential distribution along the HDD pipe, it is necessary to adopt appropriate boundary conditions of the HDD pipe and accurate holiday models of coating. A specialized deep well polarization test device was designed and employed in the field to obtain the actual polarization characteristics as the boundary condition of the HDD pipe at buried depths ranging from 2 to 25 m. The result revealed that the polarization characteristics of HDD pipe in various depths were different and the potential distribution of the actual situation was greatly different from the potential distribution of the shallow aerobic soil. The potential distribution along the HDD pipe was analyzed in two types of holiday models. The results could be used as a reference for the CP effectiveness evaluation of HDD pipes.
Evaluating the conservation benefit of circle hooks for the Atlantic Striped Bass recreational fishery
Authors: Dean Micah J. , Hoffman William S. , Gahagan Benjamin I. , Nelson Gary A. , Armstrong Michael P. 
Published: September 2024

Abstract

Objective
The Striped Bass Morone saxatilis is one of the most sought-after recreational fish species along the US Atlantic coast. Regulations and a strong conservation ethic among anglers make Striped Bass among the most frequently released coastal marine fishes. A recent rule requires anglers to use circle hooks when targeting Striped Bass with natural baits, yet the conservation benefit of this action remains unclear.

Methods
We used acoustic telemetry to monitor the fate of Striped Bass that were recreationally caught with baited hooks (n = 349) and to estimate the influence of various biological (fish size), fishery (fight time, handling time, hook location, bait type, and hook type), and environmental (water temperature and air temperature) variables on postrelease survival.

Result
A semi-quantitative score of fish release condition was the single best predictor of mortality. A broader dataset that included untagged fish (n = 716) was used to identify the best predictors of fish release condition, which included hook location and handling time.

Conclusion
Contrary to expectations, the circle hooks used in this study did not result in lower release mortality than conventional J-hooks.
An epsilon‐near‐zero circuit based on half‐mode SIW with enhanced integrability for applications of narrowband large group delay
Authors: Dai Xinfeng , Feng Wenjie , Che Wenquan 
Published: September 2024

AbstractThe tunneling effect of an epsilon‐near‐zero (ENZ) is exploited to fulfill a narrowband large group delay by using a compact half‐mode substrate integrated waveguide structure built on thin substrate. The ENZ channel possesses a finite input impedance at the tunneling frequency point, and the finite input impedance can be matched to the final I/O port simply by a quarter wavelength impedance transformer. Thus, the enhanced integrability is realized in a planar form in the proposed circuit comparing to the conventional waveguide ENZ channel. Meanwhile, in the real ENZ channel, the effective impedance is observed to be close to 50 Ω, so that the ENZ can be connected with 50 Ω microstrip directly, which has been experimentally validated. The final measured net group delay is 1.36 ns at 3.08 GHz with 3.6 dB insertion loss, and the proposed method provides an alternative for the group delay engineering.
Transformation processes in the osteoarchaeological record between the Iron Age and the Roman times with reference to the civitas Treverorum
Authors: Teegen Wolf‐Rüdiger 
Published: September 2024

AbstractThis paper discusses transformations in human behavior between the Iron Age and the Roman times in the tribal territory of the Treveri, later civitas Treverorum, located between the Rhine and the Ardennes. This aspect has been examined from two perspectives: first, from an anthropological point of view vis‐a‐vis the historical inhabitants, and second, from an archaeozoological perspective regarding domestic animals. Due to small sample sizes and/or difficulty in dating, both regarding humans and domestic animals, transformations in living conditions and animal‐keeping could mostly be outlined only for the La Tène and Roman times. Only the Celtic‐Roman cemetery of Wederath‐Belginum with continued use from middle La Tène to late antiquity offers a more complex insight into human mortality and animal offerings. People lived longer in the Roman times but had more pathologies compared with the previous La Tène period. Body height remained similar in the La Tène and Roman times. However, differences existed within specific human groups (for example, warriors and craftsmen), compared to the normal population. Sex differences in mortality persisted from La Tène to Roman times. The faunal composition in the burials, settlements, and sanctuaries also shows changes. Since the middle La Tène period, chickens have been present. The first oysters can be found in Augustean times, whereas exotic birds such as crested fowls and peacocks are found only in later Roman times and are quite rare. A new direction in animal‐keeping is demonstrated via an increasing logarithmic size index (LSI) in cattle and sheep. The multivariate methods applied in this study offer further insights into the domain and can serve as helpful tools for osteoarchaeological data analysis.
Safety of Intrauterine Transfusion Performed Beyond 34 weeks of Gestation
Authors: Youssefzadeh Ariane C. , Masri Jinnen , Korst Lisa M. , Llanes Arlyn , Hamzeh Catherine , Chmait Ramen H. 
Published: September 2024

ABSTRACTObjectiveTo describe (1) procedure‐related complications, and (2) gestational age (GA) at delivery in patients who received their final intrauterine transfusion (IUT) at ≥ 34 weeks 0 days versus at < 34 weeks 0 days.MethodsThis was a retrospective study of pregnancies treated with IUT. Procedure‐related complications were defined as any of the following within 48 h of IUT: (1) rupture of membranes or preterm delivery, (2) intrauterine infection, (3) fetal death, (4) fetal compromise resulting in emergency cesarean, or (5) neonatal death. Patient and procedural characteristics were described among patients with final IUT at ≥ 34 weeks 0 days and at < 34 weeks 0 days.ResultsWe studied 94 pregnancies with 237 IUTs; 35 (37.2%) had their last IUT at ≥ 34 weeks 0 days and 59 (62.8%) had their last IUT at < 34 weeks 0 days. Three procedure‐related complications occurred (1.3% of procedures, 3.2% of pregnancies). All resulted in emergency cesarean section; 1 case performed at < 34 weeks 0 days resulted in neonatal death. The remaining 2 occurred during IUT at ≥ 34 weeks 0 days. Pregnancies with the last IUT at ≥ 34 weeks 0 days delivered at a median GA of 37.1 weeks.ConclusionsComplications were rare. IUT performed at ≥ 34 weeks 0 days appeared safe.
Faster and greater moisture curing ethylene‐silane copolymers with good shelf stabilities
Authors: Chaudhary Bharat Indu , Bawiskar Santosh , Sengupta Saurav 
Published: September 2024

AbstractVinyltrimethoxysilane (VTMS) functionalized ethylenic polymers, in the form of reactor‐made ethylene‐silane copolymers as well as post‐reactor made silane‐grafted ethylene polymers, were evaluated for the purpose of moisture‐induced crosslinking through hydrolysis and condensation reactions. The copolymers were of 1.6 wt% or 4.2 wt% VTMS contents, and the silane‐grafted resins ranged in VTMS contents from 1.1 to 3.7 wt%. The silane‐grafted materials were very reactive under humid conditions at room temperature, resulting in very poor shelf stabilities manifested in sharp drops in their melt indices over time (changes that in the early stages were dominated mostly by resin molecular weight distribution and/or branching, and in the later stages much more by silane content). In sharp contrast, the ethylene‐silane copolymers exhibited outstanding shelf stabilities over time even at relatively high silane content, indicating desirably low reactivities in the absence of moisture‐cure catalyst. When formulated with catalyst, and exposed to humid conditions, the cure characteristics of the silane functionalized ethylene polymers varied significantly, with the fastest and greatest crosslinking observed using the ethylene‐silane copolymer of 4.2 wt% VTMS content and remarkably excellent shelf stability. Analyses of reaction rates revealed very interesting trends, depending on type of catalyst (tin or sulfonic acid) and resin.Highlights
Ethylene‐silane copolymers and silane‐grafted ethylene polymers were studied.
Copolymers exhibited vastly superior shelf stabilities than grafted materials.
Catalyst type and loading affected moisture‐induced crosslinkability.
Increased silane content in copolymer led to faster and greater crosslinking.
Best balance of crosslinkability and shelf stability obtained with copolymers.
Bipolar androgen therapy for treatment of metastatic castration‐resistant prostate cancer: A case series
Authors: Tran Elizabeth U. , Royz Eric , Yamamoto Kyra , Marley Samantha , Song Alexander , Pan Elizabeth , Lee Aaron M. , Herchenhorn Daniel , Denmeade Sam , Antonarakis Emmanuel S. , Markowski Mark , McKay Rana R. 
Published: September 2024

AbstractIntroductionAdvanced prostate cancer treatment has improved with androgen receptor signaling inhibitors (ARPI), yet many patients develop metastatic castration‐resistant prostate cancer (mCRPC), characterized by sustained androgen receptor (AR) signaling. Bipolar androgen therapy (BAT) introduces supraphysiologic testosterone levels to inhibit tumor growth, offering novel treatment for mCRPC by exploiting AR‐dependent mechanisms.Case PresentationsCase 1: A 53‐year‐old man with mCRPC, post multiple systemic therapies, initiated BAT and pembrolizumab, achieving PSA reduction and improved quality of life before progression. The patient exhibited AR amplification, which may have contributed to favorable response to BAT.Case 2: A 73‐year‐old man with recurrent prostate cancer, stable on ADT and abiraterone, experienced PSA decline with BAT to an undetectable level, maintaining stability post‐therapy discontinuation.Case 3: A 73‐year‐old man with metastatic prostate cancer, initially resistant to enzalutamide, achieved clinical benefit and disease control with BAT, although he did not meet PSA response criteria, patient had remarkable response upon enzalutamide rechallenge.Case 4: A 90‐year‐old man with localized prostate cancer, refractory to multiple treatments, experienced symptom relief and PSA reduction with BAT before progression.ConclusionBAT represents a promising treatment strategy for mCRPC. This case series underscores BAT's potential to induce significant clinical and biochemical responses, resensitize tumors to ARPIs, and improve patients' quality of life. Despite eventual progression in some cases, BAT offers a period of disease control. Further research is needed to optimize patient selection and understand the molecular determinants of BAT responsiveness.
Binary mixtures of Vanderbilt University allosteric agonist thermolysis components act as volatile spatial repellents for malaria vector mosquitoes
Authors: Martinez Luis A. , Imami Ahmed , de Jong Enzo , Romaine Ian M. , Zwiebel Laurence J. 
Published: September 2024

AbstractBACKGROUNDThe development of economically viable and environmentally neutral tools to control insects that consume or damage over 20% of global agriculture or vector human and animal disease represents one of the most important challenges of the 21st century. The suite of chemical‐based strategies currently employed to control insect populations rely primarily on insecticides, which are subject to rapid resistance and often have harmful off‐target environmental and health‐related impacts, and, to a lesser degree, repellents, which typically rely on masking attractive odors. The discovery and characterization of Vanderbilt University allosteric agonists (VUAAs), a family of small‐molecule agonists that target the highly conserved, insect‐specific odorant receptor coreceptor (Orco), raise the potential for the development of a novel repellent paradigm for vector/pest management. VUAAs have the potential to target nearly all insect olfactory sensory neurons, leading to highly aversive behavioral responses, but importantly have limited volatility, thereby reducing their utility as spatial repellents.RESULTSWe have characterized VUAA thermolysis components and identified a suite of volatiles (VUAA‐based active ingredients, VUAIs) that act specifically in novel binary combinations as robust and long‐lasting spatial repellents against Anopheline mosquitoes. In mobility‐based behavioral experiments, VUAIs act synergistically as effective spatial repellents and outperform parent VUAA compounds against host‐seeking Anopheline mosquitoes.CONCLUSIONSVUAIs are volatile alternatives to Vanderbilt University allosteric agonists (VUAAs) that have the potential for use as spatial repellents in disease vector and agricultural pest control. The repellency observed is odorant receptor coreceptor (Orco)‐dependent, supporting the hypothesis that VUAIs and VUAAs similarly target an allosteric Orco recognition site. © 2024 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Discovery of new pesticide candidates from nature: design, synthesis and bioactivity research of rutaecarpine derivatives
Authors: Chen Miao‐miao , Guo Xin , Li Tai‐qing , He Xing‐xing , Wen De‐ya , Hang Xing‐chen , Lu Ai‐dang , Zhou Zheng‐hong , Wang Qing‐min , Wang Zi‐wen 
Published: September 2024

AbstractBACKGROUNDThe invasion of viruses and fungi can cause pathological changes in the normal growth of plants and is an important factor in causing plant infectious diseases. These pathogenic microorganisms can also secrete toxic metabolites, affecting crop quality and posing a threat to human health. In this work, we selected the natural product rutaecarpine as the lead compound to achieve the total synthesis and structural derivation. The antiphytoviral activities of these compounds were systematically studied using tobacco mosaic virus (TMV) as the tested strain, and the structure–activity relationships were summarized.RESULTThe anti TMV activities of compounds 5a, 5n, 6b, and 7c are significantly higher than that of commercial antiviral agent ningnanmycin. We chose 5n for further antiviral mechanism research, and the results showed that it can directly act on viral particles. The molecular docking results further confirmed the interaction of compound 5n and coat protein (CP). These compounds also exhibited broad‐spectrum fungicidal activities against eight plant pathogens. Especially compounds 5j and 5p have significant anti‐fungal activities (EC50: 5j, 1.76 μg mL−1; 5p, 1.59 μg mL−1) and can be further studied as leads for plant‐based anti‐fungal agents.CONCLUSIONThe natural product rutaecarpine and its derivatives were synthesized, and evaluated for their anti‐TMV and fungicidal activities. Compounds 5n and 5p with good activities emerged as new antiviral and anti‐fungal candidates, respectively. This study provides important information for the research and development of the novel antiviral and fungicidal agents based on rutaecarpine derivatives. © 2024 Society of Chemical Industry.
Estimating cation exchange capacity from hygroscopic water content change
Authors: Chen Chong , Arthur Emmanuel , Zhou Hu , Song Xue , Shang Jianying , Tuller Markus 
Published: September 2024

AbstractThe existing models for estimating cation exchange capacity (CEC) from easy‐to‐measure hygroscopic water content (θh) were based on a single water activity (aw) value rather than on the processes that govern soil water vapor adsorption for a distinct aw range. Here, we present a new CEC estimation model based on θh data of 119 soils with different clay mineralogy (i.e., illitic [IL], montmorillonitic [ML], and kaolinitic [KA] samples) and organic carbon (OC) contents for the aw range from 0.23 to 0.57 (Δθ0.23–0.57) and validate its performance. Based on the hypothesis that multilayer adsorption exhibits a higher correlation with CEC than monolayer adsorption and capillary condensation, the aw range from 0.23 to 0.57 was chosen with CEC calculated as CEC = k × Δθ0.23–0.57. The performance of the new model is compared to the Arthur (2017) model and the Torrent (2015) model, which considers a single θh value. The average proportionality coefficient (k) varied with the dominant clay mineralogy of the investigated soils. For soils dominated by 2:1 clay minerals (i.e., IL and ML), the new model showed a good estimation accuracy (Nash‐Sutcliffe model efficiency [E] ≥ 0.85; root mean squared error [RMSE] ≤ 4.18 cmol(+) kg−1). The new model performed better for IL and ML samples than for KA samples, and yielded more accurate CEC estimations than the Arthur model and Torrent model for soils with 2:1 clay minerals. For soil with high OC content (>23.2 g kg−1), the new model slightly underestimated CEC (E = 0.66; RMSE = 5.87).
In Silico and In Vitro Investigation of Phytoconstituents from Flacourtia Jangomas as a Potential Candidate for the Treatment of Type 2 Diabetes Mellitus
Authors: Tomar Ritu , Mishra Shashank Shekher , Sahoo Jagannath , Rath Santosh Kumar 
Published: September 2024

AbstractFlacourtia jangomas is a plant used for centuries in Brazil, China, India, and the Malaya Peninsula to treat conditions such as diabetes, asthma, anaemia, and diarrhoea. Despite its therapeutic and economic benefits, the plant has not been popular among farmers due to its limited yield and lack of knowledge about its potential. Targeting PPARγ agonists is a promising approach for discovering and developing effective drugs to treat type 2 diabetes. Due to the activation of the PPARγ through PPARγ agonists, target genes implicated in inflammation, adipogenesis, lipid metabolism, and glucose metabolism are transcriptionally regulated. This study analysed the curated datasets of F. jangomas to identify the binding conformations of the phytoconstituents with different T2DM targets through molecular docking, molecular dynamics, and ADMET prediction approach. To determine the most favourable binding conformations of phytoconstituents that bind with the PPARγ receptors, density functional theory and principal component analysis were performed. The study reveals that the phytoconstituents of F. jangomas can act as PPARγ agonists and could be used to design and optimise the potential antidiabetic agents inspired by natural products. These findings provide a promising approach towards developing effective antidiabetic drugs.
Cyphos Nitrate Selectively Separates Y(III) from Sr(II) Present in Acidic Feed Solution: An Efficient Ionic Liquid based Extraction Process
Authors: Rout Alok , Sriram Srinivasan , Ramanathan Nagarajan 
Published: September 2024

AbstractMutual separation of Y(III) and Sr(II) from their waste solution has been an emerging research domain due to their various industrial applications. In this investigation, we emphasize the feasibility of selective separation of Y(III) from Sr(II) present in nitric acid medium using undiluted cyphos nitrate ionic liquid (IL): trihexyl(tetradecyl)phosphonium nitrate ([P66614][NO3]) as the ligating phase. The set experimental parameters were the feed phase acidity, initial nitrate ion concentration, initial feed metal ion concentration, equilibration time and temperature to unveil the efficacy of the proposed system. Efficient extraction of Y(III) selectively in presence of Sr(II) using only a salting agent in aqueous phase without additional extractant in IL phase was highlighted. A remarkable separation factor (SF) obtained for Y(III) over Sr(II) explored the efficacy of the proposed IL system. Y(III) loading in IL phase both in unirradiated and irradiated conditions was compared to evaluate the coordination behavior of irradiated moieties. In addition, a most important advantage of the proposed system is that it employs Milli‐Q water for the back extraction (stripping) of the loaded Y(III) from IL phase and does not demand any complexing agent (water soluble). This undoubtedly corroborates the economic and environmental benefits of the proposed IL system.
Synthesis and Property Evaluations of a Bio‐Based Anticorrosive Urethane Composites Containing Bisphenol a as Extender
Authors: Adeboye Samuel , Adebowale Adedamola , Durodola Bamidele , Olanipekun Bolatito , Ajanaku Kolawole , Akintayo Emmanuel , Basak Pratyay , Narayan Ramanuj , Siyanbola Tolutope 
Published: September 2024

AbstractThis article reports the synthesis of an eco‐friendly polyurethane composite system, which was successfully prepared in a one‐pot synthetic pathway by combining castor seed oil (CSO), bisphenol A (BPA), isophorone diisocyanate (IPDI), and functional hybrid nanoparticles (prepared by modifying the peripheral surface of silica with 3‐aminopropyltrimethoxysilane (APTMS). The urethane composites were cast as thin films on tin foils and mild steel and cured under atmospheric moisture. Attenuated total reflectance Fourier transform infrared (ATR‐FTIR) spectroscopy was used to characterise the cured composite films, scanning electron microscopy (SEM), energy dispersive X‐ray (EDX), X‐ray diffraction (XRD), thermogravimetric analysis (TGA), corrosion resistance, antimicrobial analysis, salt spray test, and water contact angle measurements. Our evaluations showed improved thermal and hydrophobic properties of the composite coatings. Also, the electrochemical and antimicrobial analyses clearly show resistance to corrosion and test organisms as the percentage composition of APTMS‐SiO2 increases in the urethane system.
Tailor‐Made Pyrazolopyridines and Fused Pyrazolopyridines: Recent Updates toward Sustainable Synthesis
Authors: Alam Mondal Mohabul , Ghosh Rina 
Published: September 2024

AbstractOver the last three decades, owing to labour cost, time and especially environmental issues, one‐pot synthesis of heterocyclic compounds involving tandem or multicomponent (sequential or consecutive) reactions has gained particular attention worldwide. Most of the marketed drug molecules hold one or more heterocyclic rings. Due to some side effects of several drugs along with the gradual emergence of antimicrobial resistance, the necessity for developing new heterocyclic molecules continues; special attention should be paid in this respect towards employing more one‐pot reactions for their syntheses. Pyrazolopyridines are fused heterocycles holding pyridine and pyrazole and possess a wide variety of biological and pharmaceutical properties. Several existing drug molecules also bear pyrazolopyridine scaffolds. The present perspective is an endeavour to encompass green syntheses of different isomeric pyrazolopyridine systems, most of these published during the past five years or more for a few cases.