bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bodily representations of the shame of inferiority in Sofi Oksanen’s novels
Authors: Karizs Krisztina , Bába Laura 
Published: March 2017

The range of violence comprises severe physical abuse and different methods of mental torture as well as social discrimination. Beside the traumas themselves, these acts also burden the victims with shame. Finnish writer Sofi Oksanen (born 1977) discusses these issues in her works. As a writer, Oksanen is very sensitive to social issues, discrimination and the unfairness of history. Most of her characters suffer from the shame of inferiority caused by physical or mental violence. Oksanen analyzes the influence of shame in our lives, and her characters demonstrate several different responses to the feeling.
Eyesight and our looks play an important role in recognizing or hiding the humiliating episodes of our past. Appearance often reflects all our inner struggles and represents our mental state, wherefore a given individual’s manner of personal care and habits of shaping the body reveal a great deal about the person. Personal and beauty care come up in different ways in Oksanen’s novels and have varying symbolic meanings, but they have at least one thing in common: they are related to creating a false identity, one which is more acceptable for those in the surrounding environment.
This paper analyzes the mechanism of shame connected to the feeling of inferiority, concentrating on four of Oksanen’s novels (Stalin’s Cows, Baby Jane, Purge and When the Doves Disappeared). Although violence can lead to mental disorders and the shame of inferiority also belongs to the domain of emotions, the paper focuses on the physical consequences of the victims’ mental state, which can vary from severe physical disorders to everyday personal grooming or beauty care.
Az egészségmagatartás változásának szociális-kognitív folyamatmodellje (HAPA-modell)
Authors: Teleki Szidalisz , Tiringer István 
Published: March 2017

Az egészségmagatartás alapvető szerepet játszik az egészség-betegség alakulásában, ezért az egészségkárosító viselkedések megváltoztatása az egészségpszichológiai és népegészségügyi kutatások egyik legnagyobb kihívása. A Ralf Schwarzer és kutatócsoportja által kidolgozott az egészségmagatartás szociális-kognitív folyamatmodellje (Health Action Process Approach; HAPA) — továbbfejlesztve és integrálva a korábbi egészségviselkedésekkel kapcsolatos modelleket — hatékonyan alkalmazható számos egészségviselkedés kialakítása, valamint rövid és hosszú távú módosítása érdekében. A legtöbb szociális-kognitív modell a viselkedéses szándék kialakulását hivatott magyarázni és előrejelezni, azonban mind a hétköznapi tapasztalat, mind a kutatási eredmények szerint a kialakított szándék nem minden esetben vezet tényleges viselkedéshez. A modell ezért — az ún. szándék-viselkedés-rés áthidalása érdekében — megkülönbözteti a szándék kialakulása előtti motivációs szakaszt, amely (a korábbi modellekhez hasonlóan) a szándék megformálásához, valamint a kialakulása utáni akarati (volicionális) szakaszt, amely a tényleges egészségviselkedéshez vezet. Az integrációra törekvő HAPA-modell a korábbi klasszikus modellekhez képest nagy hangsúlyt fektet a szándék kialakulása utáni tényezőkre, úgy, mint a cselekvés és az akadályokkal történő megküzdés tervezése, valamint a cselekvés fenntartásához hozzájáruló önszabályozási folyamatok és a specifikusan ezzel kapcsolatos személyes hatékonyság érzése.
Az egészségmagatartás szociális-kognitív folyamatmodelljének érvényességét és gyakorlati alkalmazhatóságát nagyszámú empirikus kutatás eredménye igazolta és támasztotta alá az elmúlt évtizedekben, számos különböző egészségviselkedés vonatkozásában (testmozgás, egészséges táplálkozás, higiénés kézmosási szokások, terápiás adherencia). Jelen tanulmány célja az egészségmagatartás szociális-kognitív folyamatmodelljének bemutatása, valamint a prevenciós és rehabilitációs munkában való alkalmazhatóságának felvázolása.
Retrospective Review of Atypical Femoral Fracture in Metastatic Bone Disease Patients Receiving Denosumab Therapy
Authors: Yang Samantha Peiling , Kim Tae Won B. , Boland Patrick J. , Farooki Azeez 
Published: March 2017

Abstract

Background
Denosumab therapy is used to reduce skeletal-related events in metastatic bone disease (MBD). There have been reports of atypical femoral fracture (AFF) in osteoporotic patients treated with denosumab but none in the context of higher dose and more frequent denosumab therapy for MBD. The goal of this study was to assess the incidence of AFF in MBD.

Patients and Methods
We conducted a retrospective review of 253 patients who received a minimum of 12 doses of denosumab at 120 mg each for MBD. To identify patients with asymptomatic atypical stress reactions in the lateral subtrochanteric femur (which precede fractures), we reviewed the skeletal images of 66 patients who had received at least 21 doses of denosumab for AFF features.

Results
These patients received a median of 17 doses, with a median treatment duration of 23 months. There was 1 case of undiagnosed clinical AFF detected after chart review and 2 cases of subclinical atypical femoral stress reaction observed on imaging review after 23 doses of denosumab over 33 months, 28 doses over 27 months, and 21 doses over 21 months, respectively. Scout computed tomography films showed diffuse cortical thickening of diaphysis with localized periosteal reaction of lateral femoral cortex. Bone scan and magnetic resonance imaging scan of 2 patients with stress reactions confirmed the diagnosis.

Conclusion
The incidence of clinical AFF in this context is 0.4% (1/253; 95% confidence interval [CI] 0.1%–2.2%), and the incidence of atypical femoral stress reaction based on imaging review is 4.5% (3/66; 95% CI 1.6%–12.5%). Clinicians should be aware of the clinical prodrome (which may or may not be present) and antecedent imaging changes associated with AFF.
Role of MGMT Methylation Status at Time of Diagnosis and Recurrence for Patients with Glioblastoma: Clinical Implications
Authors: Brandes Alba A. , Franceschi Enrico , Paccapelo Alexandro , Tallini Giovanni , De Biase Dario , Ghimenton Claudio , Danieli Daniela , Zunarelli Elena , Lanza Giovanni , Silini Enrico Maria , Sturiale Carmelo , Volpin Lorenzo , Servadei Franco , Talacchi Andrea , Fioravanti Antonio , Pia Foschini Maria , Bartolini Stefania , Pession Annalisa , Ermani Mario 
Published: March 2017

Abstract

Background
MGMT methylation status represents a powerful prognostic factor in newly diagnosed glioblastoma (GBM). Recently, its role in recurrent tumors has also been suggested; however, few data investigating the stability of this biomarker during the clinical course of the disease are available. In this study, we evaluated the rate of change of MGMT methylation status between diagnosis and first recurrence in patients who received tumor resection for recurrent GBM.

Methods
We included patients who received temozolomide concurrent with and adjuvant to radiotherapy after diagnosis of GBM and had a second surgery performed at least 3 months after radiotherapy completion. Other eligibility criteria were age ≥18 years and Eastern Cooperative Oncology Group performance status 0–2. We evaluated the MGMT methylation status by methylation-specific polymerase chain reaction.

Results
From our institutional data warehouse, 295 patients with recurrent GBM who underwent second surgery were evaluated. MGMT methylation status at both first and second surgery was available for 108 patients. MGMT was methylated in both surgeries in 38 patients (35.2%), while it was unmethylated in 43 patients (39.8%). We found a significant concordance between the first and the second MGMT methylation assessments (K = 0.500, p &lt; .001), MGMT methylation being stable in 75% of the cases.

Conclusion
MGMT methylation presents relative stability during the clinical course of GBM.
Phase I Dose-Escalation Study of Pilaralisib (SAR245408, XL147) in Combination with Paclitaxel and Carboplatin in Patients with Solid Tumors
Authors: Wheler Jennifer , Mutch David , Lager Joanne , Castell Christelle , Liu Li , Jiang Jason , Traynor Anne M. 
Published: March 2017

Abstract

Lessons Learned
Despite involvement of PI3K pathway activation in tumorigenesis of solid tumors, single-agent PI3K inhibitors have shown modest clinical activity. Preclinical evidence suggests that combining PI3K pathway inhibitors and chemotherapy can enhance antitumor effects. In patients with solid tumors, the PI3K inhibitor pilaralisib had a favorable safety profile but did not enhance the antitumor activity of paclitaxel plus carboplatin. Further clinical evaluation is warranted to identify effective combination strategies with PI3K pathway inhibitors.

Background
Pilaralisib (SAR245408) is an oral, pan-class I phosphoinositide 3-kinase (PI3K) inhibitor. This phase I dose-escalation study evaluated the maximum tolerated dose (MTD), safety, pharmacokinetics (PK), and pharmacodynamics of pilaralisib in capsule and tablet formulations, administered in combination with paclitaxel and carboplatin in patients with advanced solid tumors.

Methods
A 3 + 3 design was used. Pilaralisib was administered once daily (QD); paclitaxel (up to 175 mg/m2) and carboplatin (up to area under the curve [AUC] of 6) were administered on day 1 of 21-day cycles. An MTD expansion cohort of patients with endometrial carcinoma was included.

Results
Fifty-eight patients were enrolled. Six patients (10.3%) had dose-limiting toxicities, of which only rash (two patients, 3.4%) occurred in more than one patient. The MTD of pilaralisib tablets in combination with paclitaxel and carboplatin was determined to be 200 mg QD. The most frequently reported adverse events (AEs) of any grade were neutropenia (67.2%) and thrombocytopenia (67.2%). PK data showed no interaction between pilaralisib and paclitaxel/carboplatin. Tumor tissue showed moderate inhibition of PI3K and mitogen-activated protein kinase (MAPK) pathways. Seven of 52 evaluable patients had a partial response (PR; 13.5%).

Conclusion
Pilaralisib had a favorable safety profile but did not enhance the antitumor activity of paclitaxel plus carboplatin in solid tumors.
Comparative study of abdominal hysterectomy and vaginal hysterectomy in non-descent cases a prospective study
Authors: Mehta Kalpana , Prakash Om , Fatehpuriya Dharmendra Singh , Verma Leena 
Published: March 2017

Background: In the present times, the emphasis on minimally invasive surgery has lead to a resurgence of interest and importance of VH for non-prolapsed indications i.e. non-decent vaginal hysterectomy (NDVH) as the scar less hysterectomy. It has several benefits over abdominal hysterectomy in terms of cosmetic advantages, lesser post-operative morbidity and faster recovery. The objectives of the study was to compare and assess various factors like operative duration of surgery, intra operative blood loss, intra operative and post-operative complications, post-operative analgesia requirement, post-operative ambulation and duration of post-operative hospital stay and to put forward best route of hysterectomy.Methods: Hundred cases fulfilling, the selection criteria were included in the study. Patients were randomly divided in two groups-NDVH (non-decent vaginal hysterectomy) and abdominal hysterectomy.Results: Operative time, intra operative blood loss and post-operative morbidity was less in NDVH groups.Conclusions: Non-decent vaginal hysterectomy is a better alternative to abdominal hysterectomy in cases with benign pathology of the uterus, uterine size <14 weeks, uterus with good mobility and adequate vaginal access.
Epidemiology of orthopaedic trauma in Istanbul level 3 private hospital
Authors: Karakaş Dursun , Demiroğlu Murat 
Published: March 2017

Background: The distribution of patients who were admitted to the hospital for trauma depends on the location of hospital and the distribution of the population where the hospital is located. The aim was to answer the question regarding the distribution of orthopaedic traumas which were admitted to the emergency service of level 3 a private hospital and to be able to shed light on necessary training and equipment for the aforementioned emergency departments.Methods: The distribution of the patients who were admitted to level 3 private hospital for a year was analyzed retrospectively. The patients who admitted between January 2014 and January 2015 were divided into subgroups as upper extremity, lower extremity, vertebral disk pathology, vertebral trauma, infection and soft tissue trauma, accompanying thoracic trauma and then they were taken into consideration.Results: A total of 1538 patients admitted during a 12-month period. The number of the patients with upper extremity trauma was 539 while that of lower extremity was 423. There were 365 patients with vertebral trauma which was followed by 94 patients with pelvic trauma. The remaining patient group had thoracic trauma.Conclusions: The patients aged between 30-39 years constituted the majority of the cases in present study. The upper extremity injuries were predominant. Also, the number of male patients was higher in every month. The center where the hospital is located plays an important role in determining the age group and type of trauma.
Fundamentos para la posibilidad de una verdad artística: una lectura, en clave filosófica, de los orígenes de la producción audiovisual
Authors: Vásquez Muriel 
Published: March 2017

El artículo aborda algunas líneas de reflexión que vinculan la producción audiovisual con la filosofía, partiendo del concepto de “juguete filosófico” propuesto por Oubiña (2009) para aplicar a la invención de una serie de aparatos que se consideran antecesores del cine. Se realiza una crítica a la designación de la contradicción de términos presente en el par dicotómico juego y filosofía –idea que presenta Oubiña en su propuesta, pero que sistematiza Schjaer (2012) en una reflexión posterior– a partir de un análisis conceptual que propone nuevos sentidos para esos términos, fundamentando esta crítica en las reflexiones de dos filósofos escasamente citados en el área del cine: Lyotard (1989) y Wittgenstein (1958). La hipótesis central de la autora es, por lo tanto, que no es real ni aparente la contradicción entre los términos “juguete” y “filosófico”, como tampoco lo es entre los conceptos “juego” y “filosofía” o entre los verbos “jugar” y “filosofar”. Además, la autora justifica y fundamenta que tanto en la prehistoria, como en la historia y en lo que llama la poshistoria del cine (haciendo referencia a una arqueología de los medios que permite llegar hasta las formas actuales de producción audiovisual) no solo puede rastrearse un elemento originario científico y técnico, sino que también hay allí un componente de tipo filosófico (que no necesariamente debe traducirse como “ilusorio” o “lúdico”, como sostiene Oubiña/Schjaer) que es aquel que posibilita la caracterización estética del cine. Este componente filosófico trasciende las manifestaciones materiales de la obra y se asienta en una verdad de tipo ontológico que explica y sostiene la expresión artística cinematográfica.
Foucault: una lectura en clave discontinua en el periodo arqueológico
Authors: Choque-Aliaga Osman Daniel 
Published: March 2017

Sin duda, el tema de la discontinuidad ha llegado a acaparar la atención de un buen número de investigadores que se dedican a reflexionar en torno a la filosofía de Foucault. Posar ahora la mirada en el tema de la discontinuidad promete abrir una veta nueva de análisis que, quizá, permita revalorar el alcance de los aportes filosóficos de este pensador francés. Para tal tarea, el artículo, en un primermomento, se acerca a la noción de historia en el pensamiento foucaultiano, para a partir de ahí estudiar el desenvolvimiento que dicha noción tiene con la discontinuidad; luego, se detiene a estudiar el método arqueológico, para desentrañar si es posible analizar el tema de la discontinuidad a la luz de la arqueología. ¿Será posible mirar el tema de la discontinuidad como un rasgo propio del pensamientodel filósofo francés? Responder esta pregunta es la tarea que este trabajo pretende llevar a fin.
Agriculture Challenges: Decline of Farmers and Farmland (Study from Indonesian Family Life Survey)
Authors: Anandita Della Ayu , Patria Kinanti Zukhrufijannah 
Published: March 2017

<p>The challenge of agricultural sector in Indonesia nowadays is about land ownership which affected farmer’s welfare. Farmers in aggregates are decreasing year by year, followed by decreasing farm land because of the land reform. Another story of farmer’s income affected the land ownership of the farmers. Most of them choose to sell their own land to the land lords because of the lower income. And the lack of regeneration because farmers children choose to have a job outside agriculture sector. This paper is research about the real condition of Farmers in Indonesia between three factor of land ownerships, land reform, and lack of regeneration. Our investigation to secondary data show our hypothetical judgment: there is declining amount of farmers in Indonesia in community level. Meanwhile, that phenomenon support by evidence that there is declining farmland in community level. This study can be considering for policy implication in agriculture reform in Indonesia.</p><p><strong>Keyword </strong>: <em>land ownership, land reform, lack of farmer regeneration, farmer’s welfare</em></p>
International Financial Reporting Standards Implementation in India: Benefits and Problems
Authors: V N Sruthiya 
Published: March 2017

<p><em>International Financial Reporting Standard (IFRS) introduced by the International Accounting Standards Board (IASB is international financial reporting standard. IFRS is a single set of high quality, understandable and enforceable global accounting standards. It is a "principles based" set of standards which are drafted lucidly and are easy to understand and apply. IFRSs were adopted first time in 2005 by EU (European Union) and are now accepted or required in more than 120 countries. In India, this is in an implementation stage. This paper tries to study the implementation problems in India and make suggestions to solve the problems. The important implementation problems are cost, lack of awareness about IFRS among investors, and no uniformity in accounting guidance issued by various regulators (SEBI, IRDA, RBI) in India. The suggestions are to provide proper training and education to accounting professionals and employees about IFRS; Government has to reform the taxation system to match with IFRS. </em></p>
Knowledge Regarding Self Care Measures and Quality of Life among Patients with Chronic Renal Failure undergoing Hemodialysis
Authors: Shah Sarita , Pokharel Nabin 
Published: March 2017

Introduction: Chronic Kidney Disease (CKD) affects 500 million people worldwide. In the US there are 1400 per million of estimated prevalence or established renal failure while in the UK it is recorded more than 600 per million in 2007. This study aims to assess the knowledge on self care measured by structured knowledge questionnaire, assess the quality of life measured by WHO QOL-BREF Scale and try to find out the relationship between knowledge of self care measures and quality of life among chronic renal failure patients undergoing haemodialysis.

Methods: A non experimental descriptive correlational design with a descriptive approach was used for the study. Non probability, purposive sampling was used to select 95 CRF patients undergoing haemodialysis. The conceptual framework was based on Orem’s Self Care Model. The instruments used for data collection were a structured knowledge questionnaire and WHO QOL-BREF Scale. The structured knowledge questionnaire was divided into two sections, socio-demographic variables and knowledge regarding self care measures. The tool was divided into six areas of knowledge such as introduction, clinical features, diagnosis, evaluation, treatment, self care measures and complications of CRF. The main study was conducted among 95 CRF patients undergoing haemodialysis in the month of February to March and analysis was done by using descriptive and inferential statistics. Karl Pearson’s coefficient of correlation was used to compute the co-relation between knowledge & Quality Of Life.

Results: Among the selected 95 patients, Karl Pearson’s coefficient of correlation was found to be rxy = 0.86 since 0< rxy<1, there is positive correlation between the knowledge of self-care measures and Quality Of Life.

Conclusion: The study finding revealed that there is positive correlation between the knowledge and quality of life. As the level of knowledge increases, quality of life improves simultaneously.
From Requirements Engineering to UML using Natural Language Processing – Survey Study
Authors: Dawood Omer Salih , Sahraoui Abd-El-Kader 
Published: March 2017

In the paper process of moving from software requirements to UML diagrams has been studied. It shows the importance of this process and discusses many comparative studies in the field. A questionnaire related to the study was distributed worldwide to many research groups, academia, and industry to know the current status of using requirement management tools, knowledge of using UML in software development, frequently used UML diagrams, and the methodology used to generate UML diagrams from requirements. The paper emphasises that there is a need to do some important research in the area of requirements NLP to obtain UML diagrams, and generalize process of using automatic or semi-automatic methodology to generate UML diagrams from requirements.
Tide Height Calculation by Using the Nesting Surge Model
Authors: Towhiduzzaman Md. 
Published: March 2017

In this study, a doubly nested tide-surge model was established for the coastal region of Bangladesh. This model can be applied in coastal Belt Tide Height Calculation. A uniform grid model is being converted to the region between 210 N to 230 N and 890 E to 900 E in a grid resolution. The model equations were solved by semi-implicit finite difference technique. An appropriate tidal condition over the model domain could be generated in the sea level to be oscillatory. To the northeast corner, the Meghna River in Bangladesh discharge and rainfall distribution was taken into account. The results of Nesting Surge model are found to be a reasonable agreement with those observed data from Bangladesh inland water transport authority (BIWTA). So, the Tide Height Calculation is a significant matter here to be discussed.
KEPUASAN DAN LOYALITAS PETANI PADI TERHADAP PESTISIDA
Authors: Mustikarini Fibria , Retnaningsih Retnaningsih , Simanjuntak Megawati 
Published: March 2017

Satisfaction and loyalty are important factors to mantain and to increase the level of sales. The purpose of this study was to analyze the satisfaction and loyalty to pesticides of paddy farmers. This study used crosssectional design with 100 farmers as samplesthat were chosen by simple random sampling in the village of Cikarawang, District Dramaga, Bogor, West Java. The data was collected by interview techniques using questionnaire.This research used one of pesticides brand that used by paddy farmers at study site. The results showed that the paddy farmers have already satisfied, this result was indicated by CSI value which was 79,14 percent and the proportion of loyalty level mostly in habitual buyer level as much as 41 percent farmers. The analysis revealed a significant positive correlation between the reference group of farmers and the satisfaction of farmers to the pesticides brand. In addition, there was also a significant positive correlation between the frequency of utilization and the brand loyalty of farmers. The model suggested that the family income per capita affect significantly on brand loyalty pesticides among paddy farmers.