bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Surgery Timing and Malperfusion on Acute Type A Aortic Dissection Outcomes
Authors: Zhang Xun E. , Yu Wenda , Yang Hanci , Fu Chao , Wang Bo , Wang Lu , Li Qing-Guo 
Published: October 2024

Objective This study aimed to determine the impact of symptom-to-surgery time on mortality in acute type A aortic dissection (ATAAD) patients, with and without malperfusion.
Methods A retrospective analysis of 288 ATAAD patients was conducted. Patients were separated into the early (≤10 h) and late (>10 h) groups by symptom-to-surgery time. Data on characteristics, surgery, and complications were compared, and multivariable logistic regression determined mortality risk factors.
Results Mortality rates did not significantly differ between early and late groups. Age (odds ratio [OR] 1.09, 95% CI 1.05–1.13, p < 0.001), extracorporeal membrane oxygenation use (OR 10.73, 95% CI 2.51–45.87, p = 0.001), and malperfusion (OR 6.83, 95% CI 2.84–16.45, p < 0.001) predicted operative death. Subgroup analysis showed cerebral (OR 3.20, 95% CI 1.11–9.26, p = 0.031), cardiac (OR 5.89, 95% CI 1.32–26.31, p = 0.020), and limb (OR 6.20, 95% CI 1.75–22.05, p = 0.005) malperfusion as predictors of operative death. One (OR 6.30, 95% CI 2.39–16.61, p < 0.001), two (OR 12.79, 95% CI 2.74–59.81, p = 0.001), and three (OR 46.99, 95% CI 7.61–288.94, p < 0.001) organs malperfusion, together with Penn B (OR 7.96, 95% CI 3.04–20.81, p < 0.001) and Penn B-C (OR 12.50, 95% CI 2.65–58.87, p = 0.001) classifications predict operative mortality. Survival analysis revealed significant differences between malperfusion and no malperfusion (34% vs. 9%, p < 0.001) but not between late and early (14% vs. 21%, p = 0.132) groups. Malperfusion remained an essential predictor of operative (OR 7.06 95% CI 3.11–17.19, p < 0.001) and midterm mortality (OR 3.38 95% CI 1.97–5.77, p < 0.001) in subgroup analysis.
Conclusion Preoperative malperfusion status, rather than symptom-to-surgery time, significantly impacts both operative and midterm mortality in ATAAD patients.
Prostatic Artery Embolization: A Systematic Review Article
Authors: Atkuri Pooja , Singhal Soumil , Uthappa Mangerira Chinnappa 
Published: October 2024

AbstractSince the first case report in 2000, there has been a rapid expansion of prostatic artery embolization (PAE) as a therapy for symptomatic benign prostatic hyperplasia. The published literature and clinical experience show that this procedure is safe and effective. This article discusses the brief history, current issues in technique, and the state of the literature regarding outcomes of PAE. Current and future research topics are also discussed.
The Neck-Crossing Technique Using the Low-Profile Distal Access Catheter in Flow Diverter Placement for Dissecting Posterior Cerebral Artery Aneurysm: A Case Report
Authors: Hasebe Akiko , Nakahara Ichiro , Suyama Kenichiro , Matsumoto Shoji , Morioka Jun , Hashimoto Tetsuya , Tanabe Jun , Watanabe Sadayoshi , Suzuki Takeya , Koge Junpei 
Published: October 2024

AbstractWe report a case in which a novel distal access catheter proved successful in the placement of a flow diverter for a challenging distal cerebral artery lesion. We discuss the advantages and pitfalls of this technique and considerations for its use. A 74-year-old female presented with intermittent headaches, and was diagnosed with a dissecting aneurysm at the proximal right posterior cerebral artery with a sharp bleb, measuring 9.8 mm in diameter. Given the complex vascular anatomy, stent-assisted coil embolization was initially considered but deemed high risk for dual catheter for jailing technique with 6-Fr size guiding catheter due to the tortuosity and stenosis of the parent vessel. Therefore, we opted for flow diverter treatment, which presented its challenges during delivery. By employing a low-profile distal access catheter, Phenom Plus (outer diameter: 4.2-Fr. inner diameter: 1.13 mm; Medtronic, Minneapolis, Minnesota, United States), with a minimal ledge between it and the delivery catheter, Phenom 27 (outer diameter: 2.8-Fr, 0.91 mm; Medtronic), we successfully crossed the neck of the aneurysm with Phenom Plus and placed the flow diverter. While acknowledging potential risks, this case demonstrates the value of the neck-crossing technique using a low-profile distal access catheter as an alternative option for treating challenging peripheral artery aneurysms with flow diverters. This technique offers promise in specific situations where conventional methods pose challenges.
Lateral Calcaneal Artery Perforator/Propeller Flap in the Reconstruction of Posterior Heel Soft Tissue Defects
Authors: Balakrishnan T.M , J. Liza , Karthikeyan Abinaya , Madhurbootheswaran Srividhya , Sugumar M. , Sridharan M. 
Published: October 2024

Abstract
Introduction Posterior heel soft tissue defects with/without tendoachilles injury are difficult to reconstruct because of bony prominence, limited expendable local soft tissues, and significant donor site morbidity. In this study, we evaluate the lateral calcaneal artery (LCA) perforator/propeller flap for posterior heel soft tissue defect reconstruction.
Materials and Methods A preliminary cadaveric study was done on 22 specimens to study the course of the LCA and its perforators. The knowledge gleaned from the cadaveric study was applied in our clinical study. The clinical study was conducted from January 2018 to May 2023 in 13 patients (10 males and 3 females) with posterior heel defects. The primary movement of the perforator flaps were either V-Y advancement (n = 10) or propeller (n = 3).
Results All the flaps settled well except for superficial epidermolysis in one patient (7.69%) which healed conservatively. The average follow-up period was 14.53 months. Postoperatively, all patients had normal gait and normal range of movements. The LCA with the maximum number of perforators in the retrofibular/retromalleolar segment and the islanded flaps based on these perforators provided the excellent coverage for tendoachilles insertion defects and posterior heel defects facilitating excellent shoeability in all cases.
Conclusion The study concludes that the LCA perforator/propeller flap may be a reliable cover for the posterior heel defects with good color, texture, thickness, and contour match rendering a shoeable stable foot.
Postmastectomy Late Breast Reconstruction with Transverse Rectus Abdominis Flap after Primary Closure with Latissimus Dorsi
Authors: Micali Edmilson , Mattar André , Burattini Ana Claudia Benjamim , Gebrim Luiz Henrique , Vieira René Aloisio da Costa 
Published: October 2024

AbstractLocally advanced breast cancer (LABC) is common in countries where organized screening is not effective. Although neoadjuvant therapy increases resectability, many patients undergo mastectomy and, in some cases, flaps are necessary for primary closure of the chest wall. Despite a worse prognosis, some of these women will achieve long-term survival and may require breast reconstruction. The literature on the subject is scarce. We present the cases of two patients with LABC undergoing neoadjuvant chemotherapy, mastectomy with extensive soft-tissue resections in the anterior chest wall, and closure with extended V-Y latissimus dorsi (LD) myocutaneous flaps. After 2 years of follow-up, they were without recurrence. They were submitted to a delayed breast reconstruction using a bipedicled transverse rectus abdominis myocutaneous (TRAM) flap. To our knowledge, this is the first publication reporting secondary reconstruction with TRAM flap after primary closure of the chest wall with LD for LABC.
Cleft Palate-Lateral Synechiae Syndrome: A Case Report
Authors: Thomas Chona , K.P Divya , Raphel Princy , Jose Nikitha 
Published: October 2024

AbstractLateral synechiae (LS) are fibrous bands extending from the cleft edges to the lateral edges of the tongue. The etiology of LS is still not clear, and although they are rare, they usually coexist with cleft lip palate and other congenital anomalies. In this study, we report a case of cleft palate-lateral synechiae syndrome. In this case, the lateral synechia bands were cauterized and the patient was able to open the jaw fully. Although LS is rare, medical practitioners should have awareness regarding it so that appropriate treatment protocol can be formulated for the patients.
Pattern of Injuries in Children with Epilepsy: A Hospital-Based Case-Control Study
Authors: Mehta Raj , Saini Arushi Gahlot , Singhi Pratibha , Malhi Prahbhjot 
Published: October 2024

Abstract
Objective The aim of this study is to examine the profile and pattern of injuries in children with epilepsy (CWE) as compared with healthy controls.
Materials and Methods This prospective, cross-sectional study conducted over 1 year in a tertiary care pediatric center included consecutive CWE aged 4 to 16 years who had active seizures during the preceding 1 year. A similar number of age- and sex-matched healthy controls were enrolled. Children with acute symptomatic seizures or degenerative neurologic disorders were excluded. Standardized scales were used to assess intelligent quotient, psychopathology, seizure severity, and restriction of daily activities.
Results Two hundred and eight CWE (mean age: 107 ± 37months; range: 3.5–16 years) and an equal number of healthy controls (mean age: 108 ± 43 months; range: 3.5–16 years; p = 0.07) were evaluated. The majority of CWE had generalized epilepsy (n = 117, 59.6%) followed by focal epilepsy (n = 84, 40.3%). The mean duration of epilepsy was 47.4 ± 36.3 months. The prevalence of injury was significantly greater in CWE (n = 118/208, 56.7%) compared with controls (n = 56/208, 26.9%; p < 0.001). CWE suffered significantly greater number of 293 injuries in the past 1 year in contrast to 83 injuries in controls (p < 0.001). In CWE, the majority of injuries were unrelated to seizures (n = 85/118, 72%, 211 injuries), while only one-third (n = 33/118, 27.9%, 82 injuries) suffered seizure-related injuries. The incidence of injures unrelated to seizures and that of seizure-related injuries were similar (2.48 seizure-related injuries per person per year). Among CWE, a comparison of the injury versus noninjury group showed a significantly longer duration of epilepsy (53 ± 34 vs. 40 ± 38 months, p < 0.007), higher prevalence of underlying structural etiology in generalized epilepsy (34.7 vs. 13.3%, p < 0.001), higher mean seizure severity and restriction of daily activity scores, and higher prevalence of hyperactivity (36.4 vs. 18.9%, p = 0.006) and intellectual disability (35.6 vs. 10%, p < 0.001) in the injury group. Injuries on the head, face, and upper limb were significantly more in CWE as compared with controls, and tongue injuries were found only in CWE (p =< 0.05), and were seen significantly more as seizure-related injury (n = 7 vs. 1, p < 0.001) compared with non-seizure-related injuries. The majority of injuries in children with CWE and controls were mild in nature (n = 112, 53.8% vs. n = 54, 26%; p < 0.001).
Conclusions The prevalence of injuries among CWE aged between 4 and 16 years is high and is significantly greater than in healthy controls, although the majority of injuries are mild in severity in both and are non-seizure-related injuries. Longer duration of epilepsy, higher seizure severity, and restriction of daily activities, and higher prevalence of underlying structural etiology, hyperactivity, and intellectual disability are associated with injuries in CWE.
Diffusion Tensor Imaging of the Auditory Pathway in Prelingual Deaf Children in Comparison to Normal Hearing Children in the 1 to 7 Years of Age Group
Authors: Joy John K. , Kumar Subhash , Bhavana Kranti , Kumar Pradeep , Srinivaasan Arun , Mahto Mala 
Published: October 2024

Abstract
Objective This article aims to determine the microstructural alterations in the auditory pathway in prelingual deaf children using diffusion tensor imaging (DTI)-derived parameters—fractional anisotropy (FA) and apparent diffusion coefficient (ADC), and secondarily to evaluate these changes in rubella and cytomegalovirus (CMV) positive cases.
Method A consecutive series of consenting deaf and normal children between 1 and 7 years of age, forming the case and control groups, respectively, underwent DTI, audiological tests, and testing for rubella, CMV, and toxoplasma infections. FA and ADC were measured at four locations bilaterally: lateral lemniscus (LL), inferior colliculus, medial geniculate body, and auditory cortex (AC).
Result The mean ADC values were higher and the mean FA values were lower in cases (19 males, 21 females, mean age 2.65 years) than the controls (21 males, 19 females, mean age 4.63 years) at all eight sites. Sixteen (40%), 17 (42.5%), and 7 (17.5%) cases had severe, severe to profound, and profound hearing loss, respectively, the FA and ADC values being significantly different for LL. For rubella and CMV immunoglobulin G, 20/40and 17/40 cases were positive, respectively, 11 for both, and none for toxoplasma. Significant decrease in FA was seen at LL and AC in rubella/CMV positive cases.
Conclusion Microstructural changes are seen throughout the auditory pathway in prelingual deaf children, especially with rubella and/or CMV positive status. Further studies may pave the path to segregate out patient groups potentially more responsive to cochlear implant.
Pediatric Obesity's Effect on Open and Laparoscopic Appendectomy Outcomes
Authors: Bhatnagar Anshul , Nigam Nishtha , Anne Rohan , Santosh Sadashiv 
Published: October 2024

Abstract
Background Pediatric obesity is a common comorbid condition that may complicate pediatric surgeries, such as appendectomy. Prior research on the consequences of obesity on pediatric appendectomy outcomes have been limited by small-sample sizes and pooled analyses that do not distinguish the effects of surgical approach. Associations between surgical approach, pediatric obesity, and postoperative appendectomy outcomes thus remain unclear.
Objective To analyze postoperative appendectomy outcomes by accounting for pediatric obesity, appendectomy approach, and their interaction. This is a retrospective cohort population analysis. Nationwide data of pediatric inpatients from the United States were obtained. All pediatric patients who had an appendectomy were selected from the 2019 Kids' Inpatient Database.
Materials and Methods Outcomes variables were the length of stay and postoperative complication rate. The primary exposure variables were pediatric obesity, surgical approach (laparoscopic [LA] vs. open appendectomy [OA]), and an interaction term between the two. Control variables were patient demographics, clinical complexity, and geographic location. Multiple regression was used to determine relationships between the outcome, exposure, and control variables.
Results A total of 49,037 pediatric patients had an appendectomy, with the number of OA and LA being 4,517 and 44,420, respectively. LA patients had 5.8% (p < 0.001) shorter length of stay than OA patients. For obese patients, length of stay was 31.8% (p < 0.001) longer than for nonobese patients, but LA (compared with OA) reduced it by 19% (p < 0.007). Obesity had no effect on the number of postoperative complications.
Conclusion Obese patients had significantly longer length of stay than nonobese counterparts following OA (31.8%), but this difference was minimized for LA patients (15.81%). There was no association between complication rate, obesity, and surgical approach. Our findings will enable more accurate estimations of pediatric patients' postoperative courses and efficient allocation of limited hospital resources. Further research may wish to study the effects of other common pediatric comorbidities on other procedures.
Hyperbaric Oxygen Therapy (HBOT) in Moderate Traumatic Brain Injury (TBI): A Randomized Controlled Trial
Authors: Chaturvedi Jitender , Mago Vishal , Gupta Mohit , Singh Rahul , Goyal Nishant , Arora Rajneesh , Ruchika F.N.U. , Mudgal Shiv Kumar , Gupta Priyanka , Agrawal Sanjay , Shukla Dhaval 
Published: October 2024

Abstract
Introduction Hyperbaric oxygen therapy (HBOT) is a novel technique recently under investigation with intention to improve outcomes in traumatic brain injury (TBI). It increases the partial pressure of oxygen in the blood and tissues by inhaling pure oxygen in an environment pressurized to at least 1.4 times normal atmospheric pressure (ATM) at sea level. The rationale behind the use of HBOT in TBI is its potential to mitigate the secondary brain injury cascade initiated by the primary mechanical trauma. Tissue damage and neuroinflammation secondary to intricate and complex cellular biochemical processes are expected to be counteracted by increased oxygen availability during HBOT, which reduces oxidative stress and improves neuroplasticity.
Materials and Methods All patients, except whose legal guardians denied informed consent, with moderate TBI presenting to the neurotrauma center, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India, were included within the study period of June 2022 to July 2023. Patient allocation was randomized into two arms: namely, treatment and control arm. Simple randomization was done using randomization mobile app, RRApp. Each patient received standard of care per the Brain Trauma Foundation guidelines. Patients randomized under the treatment arm additionally received adjuvant HBOT sessions. One session daily for 10 consecutive days. Session duration was for 60 minutes each at 1.4 ATM. The primary objective of the study was to compare the Glasgow Coma Score (GCS) at discharge and 3-month post-TBI Glasgow Outcome Scale-Extended (GOS-E) among patients in the treatment arm (those who received adjuvant HBOT) with those in the control arm (those who received only standard of care).
Results The mean GCS (±standard deviation [SD]) at discharge in the treatment arm was 14.37 (±00.51) with a median of 14 and a range of 14 to 15. Comparatively, the mean GCS (±SD) at discharge in the control arm was 13.40 (±00.84) with a median of 13 and a range of 12 to 15. The difference between the two arms was statistically significant (p < 0.001). GOS-E at 3 months postinjury for the treatment arm was 7.62 ± 00.51 (mean ± SD) with a median of 8 (range: 7–8). For the control arm, GOS-E at 3 months postinjury was 6.40 ± 1.50 (mean ± SD) with a median of 7 (range: 4–8). The difference between the two arms was statistically significant (p < 0.001).
Conclusion The current study concludes that early adjuvant HBOT using 1.4 ATM with one session of one-hour daily for 10 days among adults sustaining moderate TBI significantly improves GCS at 10 days. Early adjuvant HBOT is also associated with significantly improved GOS-E at 3 months postinjury compared to standard of care alone.
The influence of subjective age and temporal focus on continuing work of the retireess: a psychological perspective
Authors: Telitsyna A. , Zabelina E. , Chestyunina Yu. , Trushina I. , Kurnosova S. 
Published: October 2024

AbstractThe demographic trend of population aging is a global phenomenon impacting the world community at large and individual national economies. Despite growing interest in the determinants of continued work among retirees, the internal (psychological) factors influencing an individual’s decision to retire after reaching retirement age have been inadequately studied. This study addresses this gap by examining psychological variables such as subjective age and temporal focus among working retirees. The results of comparing groups of working and non-working retirees revealed several key findings: 1) retirees who continue to work have a lower past focus compared to non-working retirees; 2) the subjective age of working retirees is lower (younger) than that of non-working retirees; 3) an association between a younger subjective age and current focus was found in non-working retirees, whereas in working retirees, no links were found between temporal focus and subjective age; and 4) the desire to stay young (younger social age) predicts the continuation of work in retirement. This study contributes to the development of ideas about the role of psychological time in motivating elderly people to continue their professional activities in retirement. The results strengthen the evidence that a younger subjective age, especially social age, is one of the reasons for continuing a professional career in old age. Additionally, the study enriches scientific understanding with new data on the role of temporal focus in the context of aging.
Analysing inter-state communication dynamics and roles in the networks of the International Institute of Intellectual Cooperation
Authors: Rodríguez-Casañ Rubén , Carbó-Catalan Elisabet , Solé-Ribalta Albert , Roig-Sanz Diana , Borge-Holthoefer Javier , Cardillo Alessio 
Published: October 2024

AbstractThe International Institute of Intellectual Cooperation (IIIC) was an international organisation established post-World War I, aimed to foster intellectual relations for global peace. As this institution becomes centenary, the digitisation of archival records has democratised access, sparking renewed scholar interest and eventually enabling new research avenues. Here, we examine two letter collections from IIIC’s digitised funds, focusing on administrative and artistic/literary matters. By analysing recognisable sender-receiver pairs and their geographical origins, we construct networks revealing intricate international relationships. Notably, the community structures and roles differ between administrative and literary exchanges, suggesting distinct communication dynamics. Administrative matters depict a more egalitarian distribution. In contrast, relevant literary correspondents include Western European countries exclusively, reflecting the prominence of certain geocultural areas as well as potential geopolitical influence attempts, challenging the established historical narratives on centres and peripheries, inviting a revaluation of the IIIC’s geographical organisation and intellectual cooperation during the interwar period.
Target control point position calibration based on coordinate measuring machine and global bundling optimization algorithm
Authors: Zhao Min , Ma Xing , Hu Gang Yi 
Published: October 2024

The target-based coordinate measurement system is primarily composed of a target, a camera, and a computer, relying on image processing to achieve coordinate measurement. It finds extensive applications in spatial positioning and precision measurement, such as industrial manufacturing, robot navigation, and shipbuilding. The accuracy of the target-based coordinate measurement system is highly dependent on the calibration precision of control point positions. A new method based on the calibration of control point positions using a traditional coordinate measuring machine is proposed in this paper. This method does not require the individual calculation of spatial positions for each control point; instead, it utilizes a global bundle algorithm to obtain the positions of all the control points within the field of view, thereby simplifying the calibration process. The simulation results indicate that the key factor influencing the accuracy of visual calibration is the motion range of the measured target within the field of view, and it is positively correlated with calibration accuracy. For a large-sized target, a method of stitching control points within a near-sighted distance is proposed, which achieves higher accuracy compared to full-field calibration without requiring all the control points to be present within the field of view. Experiments demonstrate that using the proposed calibration method, the standard deviations of measurement accuracy of the target-based coordinate measurement system in the x, y, and z directions are 0.01, 0.01, and 0.08 mm, respectively.