bluuebunny/crossref_metadata_2025_split huggingface dataset:
Receiver design for multicarrier transmission systems in presence of Tx/Rx imperfections
Authors: Ali Muhammad Asim , Sandhu Muhammad Yameen , Waqar Omar , Rahimo Abdul Qadir 
Published: February 2017

SummaryThe aim of this article is to design a simple receiver, which can jointly estimate the frequency selective channel impulse response, frequency independent transmit/receive IQ imbalance, and carrier frequency offset with minimal training and implementation complexity. The estimation of carrier frequency offset is performed using 2 scalable solutions. To estimate the frequency selective channel impulse response and frequency independent transmit/receive IQ imbalance, we proposed 2 different estimation techniques. The first technique is an iterative approach stemming from a doubly linear model of the transmission system in the presence of transmit/receive IQ imbalance and frequency selective channel impulse response, while the second approach is a least squares solution. Both these schemes provide a good performance/complexity trade‐off. Although the iterative estimates of channel impulse response are not optimal, they do provide a near ideal bit error performance. The proposed scheme blends seamlessly with Institute of Electrical and Electronics Engineers 802.11 standard but can be adapted to work with any orthogonal frequency‐division multiplexing standard.
Fabrication of Photoelectrochemical Glucose Biosensor in Flow Injection Analysis System Using ZnS/CdS‐Carbon Nanotube Nanocomposite Electrode
Authors: Sağlam Özlem , Dilgin Yusuf 
Published: February 2017

AbstractIn this work, a photoamperometric glucose biosensor based on glucose oxidase (GODx) was developed in flow injection analysis (FIA) system using ZnS‐CdS quantum dot (QD) modified multiwalled carbon nanotube/glassy carbon electrode (ZnS‐CdS/MWCNT/GCE). Cyclic voltammograms of the proposed electrode (GODx/ZnS‐CdS/MWCNT/GCE) showed a pair of well‐defined reversible redox peak attributing that direct electron transfer between the protein and electrode. The current of the reduction peak became more cathodic in the presence of O2due to the electrocatalytic activity of the electrode towards the reduction of dissolved O2, but reduction current shifted to a less negative value upon addition of glucose in the solution. The obtained CV currents were affected by the irradiation of the electrode surface. Thus, the photoelectrochemical biosensing of glucose in the FIA system was studied by monitoring of the changes in the electrocatalyzed reduction peak current of dissolved O2at the proposed electrode dependent on glucose concentration. The proposed photoelectrochemical FIA method has a linear response to glucose ranging from of 0.01 to 1.0 mM with detection limit of 3.0 μM under optimized conditions. Photoelectrochemical biosensor was successfully fabricated in FIA system for selective, sensitive and repeatable detection of glucose and has been satisfactorily applied to determination of glucose in real sample.
Measuring Sheet Resistances of Dielectrics Using Co‐Planar Hydrogel Electrochemical Cells with Practical Applications to Characterize the Protective Quality of Paints on Sculptures
Authors: Hosbein Kathryn N. , England Alice H. , Price Capri A. , Clare Tami Lasseter 
Published: February 2017

AbstractElectrical properties of thin dielectric films at the solid‐liquid phase boundary are an important performance characteristic of many devices, coatings and sensors. In this paper, co‐polymeric hydrogels of polyacrylic acid co‐sulfonic acid, swollen with a salt solution to act as the solid electrolyte, were used to assess interfaces using electrochemical impedance spectroscopy (EIS) in a co‐planar geometry. Silane‐modified glasses were characterized by the co‐planar hydrogel EIS cell and found to be distinguishable based on their surface monolayer chemistry. EIS measurements were also made on primed and painted metal substrates, using both test panels and an outdoor sculpture, Tony Smith's Stinger. The panels were then exposed to accelerated and outdoor weathering and showed degradation on the surface paint layers, which was observable electrochemically using EIS and confirmed visually by SEM. Electrochemical spectral features were compared between data from a standard paint‐test cell versus this co‐planar hydrogel cell; both cell types were able to measure coating capacitance, providing useful information about the condition of the bulk coating. Yet, sheet resistance (Rs) was a spectral feature seen only by the co‐planar hydrogel cell. Thus, it can be concluded that the use of such co‐planar hydrogel cells can provide an earlier warning sign to coating degradation and such cells provide a new type of spectral information that is not assessable by the standard geometry.
Creep behaviour and remediation concept for a deep‐seated landslide, Navistal, Tyrol, Austria
Authors: Hofmann Robert , Sausgruber Johann Thomas 
Published: February 2017

AbstractIn the valley of Navis, the village of Kerschbaum with 84 houses stands on a slowly downhill moving, relatively corase grained, aqua bearing earth‐flow/‐slide about 40 m thick. This secondary movement overlies a deep‐seated rock slide. The rates of movement at the surface of the earth‐flow/‐slide were between 1 und 3 cm/a before the implementation of remedial works. Starting from the geotechnical and geomechanical model of the slope, measures were developed, which were intended to reduce the movement. A monitoring system was installed to provide information about the movement and slope water conditions of the earth‐flow/‐slide and the sliding rock mass. In order to estimate the creep behaviour of the earth‐flow/‐slide, the ductility index ILZR was determined from shear tests. A simple flow law was assumed for the estimation of the change of creep rate. Measurements over a period of about 18 months after the first phase of remedial works show rates between 0.5 and 1.2 cm/a. The reduction of the rate of movement is compared with the creep model applied and the viscosity index ILZR to check the validity.
Cerebrovascular burden and depressive symptomatology interrelate over 18 years: support for the vascular depression hypothesis
Authors: Scott Rosanna , Paulson Daniel 
Published: February 2017

ObjectivePotentially incongruent research literatures suggest three divergent hypotheses about depressive symptomatology: (1) symptoms are recurrent; (2) later‐life depression results from high cerebrovascular burden (CVB); and (3) depressive symptoms contribute to comorbidities causing vascular burden. Past vascular depression research assumes that later‐life depressive symptoms relate uniquely to high CVB and not to prior, recurrent depression. This study examines these divergent hypotheses.MethodsData include 5175 participants across 18 years from the Wisconsin Longitudinal Study (mean age at 1993 baseline was 53 years; follow‐ups in 2004 and 2011). Depressive symptomatology was measured using the Center for Epidemiological Studies Depression. CVB was operationalized as hypertension, high blood sugar, diabetes, and other heart problems. Hypotheses were examined via a cross‐lagged structural equation model and logistic regression.ResultsModel fit was acceptable (root mean square error of approximation (RMSEA) = 0.047; comparative fit index = 0.963). Hypotheses 1 and 2 were supported. Depressive symptomatology at 2004 and 2011 follow‐ups was predicted by earlier depressive symptomatology and prior CVB. Hypothesis 3 was partially supported; depressive symptomatology in 2004 predicted subsequent CVB. Logistic regression results were that CVB predicted clinically significant depressive symptoms based on the Center for Epidemiological Studies Depression clinical cutoff.ConclusionsCerebrovascular burden in midlife predicts depressive symptomatology in later‐life, even after accounting for prior depressive symptomatology, supporting a fundamental assumption of the vascular depression hypothesis. Midlife depressive symptomatology also predicted escalation of CVB in later‐life. Results suggest a process model of later‐life depressive symptom development that interrelates CVB and depressive symptoms throughout the life span and have clinical implications for the interruption of this process through the integration of primary care and behavioral health specialists. Copyright © 2017 John Wiley & Sons, Ltd.
Consequences of clinical case management for caregivers: a systematic review
Authors: Corvol Aline , Dreier Adina , Prudhomm Joachim , Thyrian Jochen René , Hoffmann Wolfgang , Somme Dominique 
Published: February 2017

ObjectiveInformal caregivers are deeply involved in the case management process. However, little is known about the consequences of such programs for informal caregivers. This systematic literature review, reported according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses statement, addressed the consequences of clinical case management programs, whether positive or negative, for caregivers of frail older persons or persons with dementia.MethodsWe systematically identified and analyzed published randomized trials and quasi‐experimental studies comparing case management programs to usual care, which discussed outcomes concerning caregivers.ResultsSixteen studies were identified, and 12 were included after quality assessment. Seven identified at least one positive result for caregivers, and no negative effect of case management has been found. Characteristics associated with positive results for caregivers were a high intensity of case management and programs specifically addressed to dementia patients.ConclusionsDespite the numerous methodological challenges in the assessment of such complex social interventions, our results show that case management programs can be beneficial for caregivers of dementia patients and that positive results for patients are achieved without increasing caregivers' burden. Copyright © 2017 John Wiley & Sons, Ltd.
Effects of chin‐up posture on the sequence of swallowing events
Authors: Calvo Irene , Sunday Kirstyn L. , Macrae Phoebe , Humbert Ianessa A. 
Published: February 2017

ABSTRACTBackgroundChin‐up posture is frequently used to manage oral dysphagia after head and neck cancer. This prospective study investigates the effects of chin‐ups on the sequence of pharyngeal swallowing events.MethodsTwelve healthy young adults performed 45 consecutive swallows of 5 mL water across 3 phases on videofluoroscopy: 5 swallows in the neutral head position; 30 swallows during chin‐up posture; and 10 swallows in the neutral head position. Swallowing kinematic and bolus flow measures for 9 swallowing events were recorded. Linear trends were analyzed across 30 chin‐up swallows; pairwise comparison was used to compare the 3 phases.ResultsTime to hyoid peak and laryngeal vestibule closure changed abruptly during chin‐up swallowing compared to the initial neutral position. No measure changed across 30 chin‐up swallows. Time of hyoid burst decreased upon returning to the neutral position.ConclusionOur findings indicate that chin‐up posture challenges the pharyngeal sequence of events for both swallowing kinematics and bolus flow. © 2017 Wiley Periodicals, Inc. Head Neck 39: 947–959, 2017
Experimental study on thermal performance of optimum PG brine as a radiator coolant
Authors: Sahoo Rashmi Rekha 
Published: February 2017

AbstractThe present study deals with the experimental impact of an alternative heat transfer fluids for overall performance improvement for radiators. Water and water mixed with anti‐freezing agents such as ethylene glycol (EG) and propylene glycol (PG) are the traditional coolants for an automotive radiator. Comparison of experimental and numerical analysis of optimum brine solution, that is 25% of propylene glycol and water as coolant for the rectangular fin radiator, has been well discussed. A closed loop test rig was designed, and fabricated with a wind tunnel section to achieve uniform velocity at the test section of the rectangular radiator and was tested for performance. Experimental runs were conducted at varying operating temperatures which included the runs for water, and an optimum propylene glycol brine solutions at 70 °C and 80 °C with various flow rates. Results show the energy performance of an optimum brine solution was nearly similar to that of water at high temperatures. The Nusselt number, heat transfer coefficient, and heat transfer rate for an optimum propylene glycol brine is nearly the same as water at 80 °C with a maximum deviation of 15%, 5.7%, and 6.6%, respectively, for theoretical and experimental result comparisons. Air side and coolant side pressure drops had a maximum deviation of 3.66% and 6.6%, respectively. Air and coolant exit temperatures had a deviation of 5% and 3.5%, respectively, with an air frontal velocity of 4.6 m/s in a rectangular fin radiator for an optimum brine solution used as coolant for the automotive radiator. The optimum propylene glycol brine may be environmentally beneficial.
Student Award for Outstanding Research Winner in the Undergraduate Category for the 2017 Society for Biomaterials Annual Meeting and Exposition, April 5–8, 2017, Minneapolis, Minnesota: Development and characterization of stimuli‐responsive hydrogel microcarriers for oral protein delivery
Authors: O'Connor Colleen , Steichen Stephanie , Peppas Nicholas A. 
Published: February 2017

AbstractA family of pH‐responsive terpolymers composed of methacrylic acid (MAA), N‐vinyl pyrrolidone (NVP), and poly(ethylene glycol) monomethylether monomethacrylate (PEGMMA) have been developed and evaluated for their pH‐responsive swelling behavior, protein‐loading capabilities, and cytocompatibility. These terpolymer hydrogels, designated as P((MAA‐co‐NVP)‐g‐EG), were synthesized with varying PEG chain lengths and monomer feed ratios. The incorporation of MAA into the terpolymer structure was quantified with potentiometric titration. Equilibrium and dynamic swelling studies confirmed the pH‐responsive behavior of the hydrogel, with the system remaining collapsed/complexed in acidic pH conditions and swollen/decomplexed in neutral pH conditions. The ability of the hydrogels to partition protein into the swollen network was assessed for two model proteins of varying molecular weight: insulin and porcine growth hormone. Finally, the cytocompatibility of the hydrogels in the presence of two model intestinal cell lines was investigated and confirmed minimal cytotoxicity at and below 2.5 mg/mL. The developed P((MAA‐co‐NVP)‐g‐EG) hydrogels exhibit unique properties that could potentially be utilized for drug delivery and separation applications. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1243–1251, 2017.
Metastatic neuroblastoma diagnosed on prenatal sonographic examination performed for decreased fetal movement
Authors: Chapa Hector O. , Geddie Steven Gywnn , Flores Rebecca 
Published: February 2017

ABSTRACTWe report a case of fetal neuroblastoma presenting with massive liver metastasis diagnosed during the biophysical profile sonographic examination performed for decreased fetal movement. The patient presented at 37 weeks' gestation with limited fetal movement over 24 hours. Biophysical profile showed marked polyhydramnios and an enlarged abdomen filled with a homogeneous mass lesion suspicious for liver metastasis. Primary urgent cesarean section was performed revealing a cachectic neonate with a rigid and grossly distended abdomen. Neonatal evaluation confirmed the etiology of the abdominal mass to be liver metastasis from neuroblastoma. The child died on the 46th day. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 45:502–506, 2017
Diagnostic value of renal perfusion in patients with chronic kidney disease using 3D arterial spin labeling
Authors: Cai Yu‐zhe , Li Zhi‐cheng , Zuo Pan‐li , Pfeuffer Josef , Li Yu‐ming , Liu Fang , Liu Rong‐bo 
Published: February 2017

PurposeTo evaluate the diagnostic value of 3D arterial spin labeling (ASL) for noninvasive quantification of renal blood flow (RBF) in patients with chronic kidney disease (CKD).Materials and MethodsCKD patients (n = 27) and healthy volunteers (n = 36) underwent renal 3T ASL magnetic resonance imaging, with inversion times from 1200 to 2000 msec for volunteers in the preliminary test, and 1800 to 2000 msec for volunteers and CKD patients in the formal experiments. The cortical RBFs were compared, and a correlation between RBF and estimated glomerular filtration rate (eGFR) was evaluated.ResultsFor healthy volunteers, RBF values increased with TIs from 1200 to 1600 msec, but were almost constant at TIs from 1600 to 2000 msec. The cortical RBF values of CKD patients were lower than that of healthy volunteers at TIs from 1800 to 2000 msec. In addition, the CKD patients had lower cortical RBF values than the healthy volunteers (P < 0.01 for both), and their RBF values positively correlated with eGFR.Conclusion3D ASL is a potential noninvasive method for measuring renal perfusion that can provide valuable information for clinical CKD diagnosis.Level of Evidence: 1Technical Efficacy: Stage 3J. MAGN. RESON. IMAGING 2017;46:589–594
Respiratory motion artifacts during arterial phase imaging with gadoxetic acid: Can the injection protocol minimize this drawback?
Authors: Polanec Stephan H. , Bickel Hubert , Baltzer Pascal A.T. , Thurner Patrick , Gittler Florian , Hodge Jacqueline C. , Bashir Mustafa R. , Ba‐Ssalamah Ahmed 
Published: February 2017

PurposeTo determine which of three gadoxetic acid injection techniques best reduced the contrast‐related arterial‐phase motion artifacts.Materials and MethodsThis Institutional Review Board (IRB)‐approved, retrospective study included a cohort of 78 consecutive patients who each had serial gadoxetic acid‐enhanced 3.0T magnetic resonance imaging (MRI) of the liver (0.025 mmol/kg body weight) performed with at least two of three injection techniques: M1 test bolus, undiluted, power‐injected 1 mL/s; M2 test bolus, diluted 50% with saline, power‐injected 1 mL/s; M3 fixed delay, undiluted, manually injected. Blinded to the injection method, three readers independently rated the randomized images for arterial‐phase motion artifacts, arterial‐phase timing, and arterial‐phase lesion visibility using a four‐point Likert scale.ResultsRegarding respiratory artifacts, gadoxetic acid arterial‐phase images were judged better with M3 (2.7 ± 0.7) and were significantly less than those with M1 (2.1 ± 1.1) (P = 0.0001). Arterial‐phase M2 (2.50 ± 0.89) images were rated significantly better than arterial‐phase M1 images (P = 0.012), but the difference between arterial‐phase images with M3 and M2 scores was not statistically significant (P = 0.49). Arterial‐phase timing was significantly better for M1 compared to M3, and for M2 compared to M3 (P < 0.0001 for both). The area under the curve was 0.59–0.68. However, there was no significant difference between M1 and M2 (P = 0.35). With regard to arterial‐phase lesion visibility, there was no significant difference in the ratings between any of the three injection techniques (P = 0.29–0.72). Interreader agreement was moderate to substantial (κ = 0.41–0.62).ConclusionA diluted, power‐injected protocol (M2) seems to provide good timing and minimize artifacts compared with two other injection methods. No significant difference was found in lesion visibility between these three methods.Level of Evidence: 3Technical Efficacy: Stage 1J. Magn. Reson. Imaging 2017;46:1107–1114.
Cowpea: a legume crop for a challenging environment
Authors: Carvalho Márcia , Lino‐Neto Teresa , Rosa Eduardo , Carnide Valdemar 
Published: February 2017

AbstractCowpea is a grain legume native from Africa and is a primary source of protein for millions of people in sub‐Saharan Africa and other parts of the developing world. The main important characteristics of this crop include a good protein quality with a high nutritional value, its nitrogen‐fixing ability, and an ability to be more drought‐ and heat‐tolerant than most of its legume relatives. In a research perspective, studies of cowpea are relatively scarce, despite its relevance to agriculture in the developing world and its resilience to stress. The present review provides an overview of different aspects of cowpea, with a special emphasis on the molecular markers for assessing genetic diversity, as well as on biochemical and transcriptomic data with respect to evaluating cowpea drought stress tolerance. The integration of both datasets will be useful for the improvement of cowpea because research on drought stress tolerance is of major interest for this crop in a challenging environment. © 2017 Society of Chemical Industry
On the Phase Shifts in the Dynamics of the H2O2–Na2S2O3–H2SO4–CuSO4 Oscillator Revealed by Comparison of Potentiometric Responses of Different Indicator Electrodes
Authors: Jędrusiak Mikołaj , Matyszczak Grzegorz , Orlik Marek 
Published: February 2017

ABSTRACTThe dynamics of the H2O2–Na2S2O3–H2SO4–CuSO4 homogeneous pH oscillator was studied in the flow reactor potentiometrically using different sensors: platinum electrode, Cu(II) ion‐selective electrode (Cu‐ISE), and pH‐electrode. It was found that for the flow rates close to two bifurcation values, between which the oscillations exist, there is a detectable phase shift between the response of the Cu‐ISE and other electrodes, while it practically vanishes for the intermediate flow rates. To explain both the oscillations of the Cu‐ISE potential and the relevant phase shift, the system's dynamics was studied both experimentally and numerically. The literature kinetic mechanism of the pH oscillator was extended for the dynamics of the copper(II) and copper(I) species in the form of thiosulfate complexes, and kinetic parameters of the redox equilibria, ensuring the oscillations, were estimated. It was found that the phase shift at the relatively low flow rates occurs due to limited efficiency of the supply of CuSO4 catalyst, as the species of lowest concentration, to the reactor, and therefore it can be minimized either by increasing the flow rate of all reactants or, alternatively, by enhancing the model concentration of CuSO4 in the feeding stream, for its fixed flow rate. This work is one more proof that it is useful to monitor the dynamics of the homogeneous oscillatory systems with more than one electrode, if the experimental potential–time courses are to be explained in terms of an appropriate kinetic mechanism.
The Search for Potent, Small‐Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat
Authors: Zagni Chiara , Floresta Giuseppe , Monciino Giulia , Rescifina Antonio 
Published: February 2017

AbstractHistone deacetylases (HDACs) play a crucial role in the remodeling of chromatin, and are involved in the epigenetic regulation of gene expression. In the last decade, inhibition of HDACs came out as a target for specific epigenetic changes associated with cancer and other diseases. Until now, more than 20 HDAC inhibitors (HDACIs) have entered clinical studies, and some of them (e.g., vorinostat, romidepsin) have been approved for the treatment of cutaneous T‐cell lymphoma. This review provides an overview of current knowledge, progress, and molecular mechanisms of HDACIs, covering a period from 2011 until 2015.