bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamical reconstruction of the $$\Lambda $$CDM model in hybrid metric-Palatini gravity
Authors: Rosa João Luís 
Published: September 2024

AbstractIn this work, we apply the formalism of dynamical systems to analyze the viability of the $$\Lambda $$
Λ
CDM model in a generalized form of the hybrid metric-Palatini gravity theory written in terms of its dynamically equivalent scalar–tensor representation. Adopting a matter distribution composed of two relativistic fluids described by the equations of state of radiation and pressureless dust, one verifies that the cosmological phase space features the usual curvature-dominated, radiation-dominated, matter-dominated, and exponentially accelerated fixed points, even in the absence of a dark energy component. A numerical integration of the dynamical equations describing the system, subjected to initial conditions consistent with the cosmographic observations from the Planck satellite and weak-field solar system dynamics, shows that cosmological solutions mimicking the behavior of the $$\Lambda $$
Λ
CDM model in General Relativity (GR) are attainable in this theory, with the deviations from GR being exponentially suppressed at early-times and the scalar-field potential effectively playing the role of dark energy at late times.
Probing the spatial distribution of gluons within the proton in the coherent vector meson production at large-|t|
Authors: Gonçalves Victor P. , Moreira Bruno D. , Santana Luana 
Published: September 2024

AbstractThe coherent production of vector mesons in photon–hadron interactions is considered one of the most promising observables to probe the QCD dynamics at high energies and the transverse spatial distribution of the gluons in the hadron wave function. In this paper, we perform an exploratory study about the dependence of the transverse momentum distributions, $$d\sigma /dt$$

d
σ
/
d
t

, on the model assumed for the proton density profile. We consider a set of non-Gaussian profiles and include them in the forward dipole–proton scattering amplitude associated with the IP-sat model. We demonstrate that the predictions for $$d\sigma /dt$$

d
σ
/
d
t

are similar in the HERA kinematical range, but are very distinct for values of t that will be probed in future colliders. In particular, the presence of diffractive dips in the t-distributions associated with the production of $$J/\Psi $$

J
/
Ψ

and $$\rho $$
ρ
mesons is strongly dependent on the model assumed for the density profile. Similar conclusions are also derived when the non-linear effects on the dipole–target interaction are disregarded. Our results indicate that a future study of the coherent vector meson production at large-t will be useful to constrain the spatial distribution of gluons within the proton.
A Conceptual Map of Knowledge Transfer in Occupational Therapy Clinical Practice in Central South Africa
Authors: Swanepoel Azette , Janse van Vuuren Corlia , Nayar Shoba 
Published: September 2024

Introduction: Empirical evidence has confirmed that all types of knowledge (propositional, procedural, personal, and client) contribute to evidence‐based practice (EBP) and should be transferred in clinical practice to inform quality service delivery. However, it is unclear how the integration of the types of knowledge that are transferred in clinical practice manifests. Given this gap in understanding, the current research sought to build a conceptual map of knowledge transfer in clinical practice in central South Africa.Method: A qualitative approach was followed, and data to build the conceptual map was obtained from a scoping review that explored the landscape of knowledge transfer in occupational therapy clinical practice, nine semistructured interviews with occupational therapists working in central South Africa, and a Q Method survey.Results: The conceptual map–building process delivered a multidimensional, multidirectional conceptual map consisting of four concepts (theory and research, practice experience, patient–therapist relationship, and patient’s voice in clinical practice) and four types of knowledge (propositional, procedural, personal, and client). The results show the integration of the types of knowledge and confirm that knowledge transfer in clinical practice is a complex and ongoing process.Conclusion: The conceptual map, a first of its kind in South Africa, presents empirical evidence of knowledge that is created and transferred in clinical practice in central South Africa. The conceptual map might provide a framework for collaboration amongst all stakeholders, such as patients, occupational therapists, and academics, to produce practice guidelines and occupational outcome measures to support evidence‐based clinical practice.
Tuning Responses to Polatuzumab Vedotin in B-cell Lymphoma
Authors: Leveille Etienne , Kothari Shalin , Cosgun Kadriye N. , Mlynarczyk Coraline , Müschen Markus 
Published: September 2024

Summary:
Polatuzumab vedotin, an antibody–drug conjugate targeting CD79B, is the first new drug approved for first-line therapy of diffuse large B-cell lymphoma in more than two decades, although factors determining treatment responses to polatuzumab vedotin remain unknown. Two new studies identified central mechanisms of lower sensitivity, namely reduced accessibility of the CD79B epitope through N-linked glycosylation of CD79B and lower CD79B surface expression levels due to the activity of the KLHL6 E3 ligase.
See related article by Corcoran et al., p. 1653 (6)
See related article by Meriranta et al. (7).
Efficacy and Safety of Catheter-Based Radiofrequency Renal Denervation in Chinese Patients With Uncontrolled Hypertension: The Randomized, Sham-Controlled, Multi-Center Iberis-HTN Trial
Authors: Jiang Xiongjing , Mahfoud Felix , Li Wei , Dong Hui , Yu Jing , Yu Shuhua , Chen Xiaoping , Wang Peijian , Li Zhiqiang , Lauder Lucas , Wang Zhifang , Ji Zheng , Dong Yifei , Han Bing , Zhu Zhiming , Chen Yulin , Xu Jianzhong , Zhao Xingsheng , Fan Weidong , Xie Wen , Hubbard Brad , Hu Xi , Kario Kazuomi , Gao Runlin 
Published: September 2024

BACKGROUND:
Renal denervation (RDN) can lower blood pressure (BP) in patients with hypertension in both the presence and absence of medication. This is a sham-controlled trial investigating the safety and efficacy of RDN in China.

METHODS:
This prospective, multicenter, randomized, patient- and outcome-assessor-blinded, sham-controlled trial investigated radiofrequency RDN in patients with hypertension on standardized triple antihypertensive therapy. Eligible patients were randomized 1:1 to undergo RDN using a multi-electrode radiofrequency catheter (Iberis; Shanghai Angiocare Medical Technology, Shanghai, China) or a sham procedure. The primary efficacy outcome was the between-group difference in baseline-adjusted change in mean 24-hour ambulatory systolic BP from randomization to 6 months.

RESULTS:

Of 217 randomized patients (mean age, 45.3±10.2 years; 21% female), 107 were randomized to RDN and 110 were randomized to sham control. At 6 months, there was a greater reduction in 24-hour systolic BP in the RDN (−13.0±12.1 mm Hg) compared with the sham control group (−3.0±13.0 mm Hg; baseline-adjusted between-group difference, −9.4 mm Hg [95% CI, −12.8 to −5.9];
P
<0.001). Compared with sham, 24-hour diastolic BP was lowered by −5.0 mm Hg ([95% CI, −7.5 to −2.4];
P
<0.001) 6 months after RDN, and office systolic and diastolic BP was lowered by −6.4 mm Hg ([95% CI, −10.5 to −2.3];
P
=0.003) and −5.1 mm Hg ([95% CI, −8.2 to −2.0];
P
=0.001), respectively. One patient in the RDN group experienced an access site complication (hematoma), which resolved without sequelae. No other major device- or procedure-related safety events occurred through follow-up.

CONCLUSIONS:
In this trial of Chinese patients with uncontrolled hypertension on a standardized triple pharmacotherapy, RDN was safe and reduced ambulatory and office BP at 6 months compared with sham.

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02901704.
Sex Differences in Hypertension and Its Management Throughout Life
Authors: Yeo Wan-Jin , Abraham Rahul , Surapaneni Aditya L. , Schlosser Pascal , Ballew Shoshana H. , Ozkan Bige , Flaherty Carina M. , Yu Bing , Bonventre Joseph V. , Parikh Chirag R. , Kimmel Paul L. , Vasan Ramachandran S. , Coresh Josef , Grams Morgan E. 
Published: September 2024

BACKGROUND:
The prevalence of hypertension and uncontrolled hypertension may differ by age and sex.

METHODS:
We included participants in the Atherosclerosis Risk in Communities study at seven study visits over 33 years (visit 1: 15 636 participants; mean age, 54 years; 55% women), estimating sex differences in prevalence of hypertension (systolic blood pressure ≥130 mm Hg; diastolic blood pressure ≥80 mm Hg; or self-reported antihypertension medication use) and uncontrolled hypertension (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg) using unadjusted and comorbidity-adjusted models.

RESULTS:

The prevalence of hypertension increased with age from 40% (ages, 43–46 years) to 93% (ages, 91–94 years). Within hypertensive individuals, the prevalence of uncontrolled hypertension was higher in men (33%) than women (23%) at ages 43 to 46 years but became higher in women than men starting at ages 61 to 64, with 56% of women and 40% men having uncontrolled hypertension at ages 91 to 94. This sex difference was not explained by differences in coronary heart disease, diabetes, body mass index, estimated glomerular filtration rate, number of antihypertension medications, classes of medications, or adherence to medications. In both sexes, uncontrolled hypertension was associated with a higher risk for chronic kidney disease progression (hazard ratio, 1.5 [1.2–1.9];
P
=4.5×10
−4
), heart failure (hazard ratio, 1.6 [1.4–2.0];
P
=8.1×10
−7
), stroke (hazard ratio, 2.1 [1.6–2.8];
P
=1.8×10
−8
), and mortality (hazard ratio, 1.5 [1.3–1.6];
P
=6.2×10
−19
).

CONCLUSIONS:
Sex differences in the prevalence of hypertension and uncontrolled hypertension vary by age, with the latter having implications for health throughout the life course.
Is Clot Composition Associated With Cause of Stroke? A Systematic Review and Meta‐Analysis
Authors: Sujijantarat Nanthiya , Templeton Kelsey A. , Antonios Joseph P. , Renedo Daniela , Koo Andrew B. , Haynes Joseph O. , Fathima Bushra , Amllay Abdelaziz , Nowicki Kamil , Huttner Anita , Giles James A. , Navaratnam Dhasakumar , Sansing Lauren H. , Hebert Ryan M. , King Joseph T. , Matouk Charles C. 
Published: September 2024

Background
Prior studies have suggested an association between clot histological composition and cause of stroke. However, the results have been conflicting. Our objective is to provide an updated systematic review and meta‐analysis of the association between clot histological composition and cause of stroke for patients who underwent mechanical thrombectomy.

Methods
We searched Cochrane Library, Embase, and MEDLINE databases for English language articles reporting clot histology in adult patients who underwent mechanical thrombectomy for acute ischemic stroke between January 2000 and March 2024. Studies included reported on the association between causes of clots and the quantity of red blood cells and fibrin and/or platelets. Random effects meta‐analysis was used.

Results
A total of 448 records were identified. Of these, 25 studies were included in the qualitative synthesis, and 17 contained data in a format suitable for quantitative review. A total of 1656 patients had continuous data on clot composition and its association with cause of stroke. The pooled mean percentage difference between the cardioembolic group and the large artery atherosclerosis /noncardioembolic group was −10.3% (95% CI −16.3% to −4.4%) for red blood cells and +9.9% (95% CI +4.5% to +15.4%) for fibrin and/or platelets. Only 7 studies reported on overall white blood cells quantity. Of these, the pooled percentage difference of white blood cells between the cardioembolic group and the large artery atherosclerosis/non‐cardioembolic group was +1.1% (95% CI +0.3% to +1.9%).

Conclusion
Our results suggest that cardioembolic clots have higher fibrin and/or platelets and lower red blood cells compared with large artery atherosclerosis/noncardioembolic clots. However, these differences are unlikely to be of clinical utility in differentiating cause of stroke. Future studies would benefit from more rigorous analysis of clot constituents beyond cellular composition.
The strain on scientific publishing
Authors: Hanson Mark A. , Barreiro Pablo Gómez , Crosetto Paolo , Brockington Dan 
Published: September 2024

Abstract
Scientists are increasingly overwhelmed by the volume of articles being published. The total number of articles indexed in Scopus and Web of Science has grown exponentially in recent years; in 2022 the article total was ∼47% higher than in 2016, which has outpaced the limited growth—if any—in the number of practicing scientists. Thus, publication workload per scientist has increased dramatically. We define this problem as “the strain on scientific publishing.” To analyze this strain, we present five data-driven metrics showing publisher growth, processing times, and citation behaviors. We draw these data from web scrapes, and from publishers through their websites or upon request. Specific groups have disproportionately grown in their articles published per year, contributing to this strain. Some publishers enabled this growth by hosting “special issues” with reduced turnaround times. Given pressures on researchers to “publish or perish” to compete for funding, this strain was likely amplified by these offers to publish more articles. We also observed widespread year-over-year inflation of journal impact factors coinciding with this strain, which risks confusing quality signals. Such exponential growth cannot be sustained. The metrics we define here should enable this evolving conversation to reach actionable solutions to address the strain on scientific publishing.
ARN: Analogical Reasoning on Narratives
Authors: Sourati Zhivar , Ilievski Filip , Sommerauer Pia , Jiang Yifan 
Published: September 2024

Abstract
As a core cognitive skill that enables the transferability of information across domains, analogical reasoning has been extensively studied for both humans and computational models. However, while cognitive theories of analogy often focus on narratives and study the distinction between surface, relational, and system similarities, existing work in natural language processing has a narrower focus as far as relational analogies between word pairs. This gap brings a natural question: can state-of-the-art large language models (LLMs) detect system analogies between narratives? To gain insight into this question and extend word-based relational analogies to relational system analogies, we devise a comprehensive computational framework that operationalizes dominant theories of analogy, using narrative elements to create surface and system mappings. Leveraging the interplay between these mappings, we create a binary task and benchmark for Analogical Reasoning on Narratives (ARN), covering four categories of far (cross-domain)/near (within-domain) analogies and disanalogies. We show that while all LLMs can largely recognize near analogies, even the largest ones struggle with far analogies in a zero-shot setting, with GPT4.0 scoring below random. Guiding the models through solved examples and Chain-of-Thought reasoning enhances their analogical reasoning ability. Yet, since even in the few-shot setting, the best model only performs halfway between random and humans, ARN opens exciting directions for computational analogical reasoners.
Satisfaction with Healthcare Services Among rae Community
Authors: Qelaj Erikene , Alidema Fitim , Fejz Hajrullah 
Published: September 2024

Abstract
Most members of all three communities often live on the margins of society, with high levels of unemployment and low levels of education. Aim – To assess the experiences and satisfaction of the rae community with the health services. Methodology – The research was in the period March – June 2023. The criteria for inclusion were clear and based on this, 120 participants were selected. Results – The participants were treated with respect (80%), they did not feel treated differently from others (78%), there were no obstacles in communication (70%), there were no delays in receiving services (80%) and did not feel discriminated or prejudiced (88%). The 90% of them graded healthcare services as 5 on a scale of 1–5. Conclusions – We can conclude that most of the respondents expressed satisfaction with the health services they received, which was the main goal of our research.
Finding Common Ground: the Right to Be Free from Incitement to Discrimination, Hostility, and Violence in the Digital Age
Authors: Dias Talita 
Published: September 2024

Abstract
Atrocities do not happen in a vacuum and incitement to discrimination, hostility, and violence is one of their main drivers – offline and now online. But states continue to disagree about how to deal with inciting speech. Under international law, there is much debate about whether obligations to prohibit incitement, such as the one found in Article 20(2) of the International Covenant on Civil and Political Rights, applies universally to all states. This article finds common ground in the overlooked human right to be free from incitement to discrimination, reflected in Article 7 of the Universal Declaration of Human Rights and binding on all states under customary international law. It gives rise to common but differentiated responsibilities to refrain from and protect individuals and groups from different forms of incitement. In the digital age, this right can be protected by a range of online content governance measures that this article explores.
Clustering-Based Spatial Interpolation of Parametric Postprocessing Models
Authors: Baran Sándor , Lakatos Mária 
Published: September 2024

Abstract
Since the start of the operational use of ensemble prediction systems, ensemble-based probabilistic forecasting has become the most advanced approach in weather prediction. However, despite the persistent development of the last three decades, ensemble forecasts still often suffer from the lack of calibration and might exhibit systematic bias, which calls for some form of statistical postprocessing. Nowadays, one can choose from a large variety of postprocessing approaches, where parametric methods provide full predictive distributions of the investigated weather quantity. Parameter estimation in these models is based on training data consisting of past forecast-observation pairs; thus, postprocessed forecasts are usually available only at those locations where training data are accessible. We propose a general clustering-based interpolation technique of extending calibrated predictive distributions from observation stations to any location in the ensemble domain where there are ensemble forecasts at hand. Focusing on the ensemble model output statistics (EMOS) postprocessing technique, in a case study based on 10-m wind speed ensemble forecasts of the European Centre for Medium-Range Weather Forecasts, we demonstrate the predictive performance of various versions of the suggested method and show its superiority over the regionally estimated and interpolated EMOS models and the raw ensemble forecasts as well.
Specialized short term crisis intervention for patients with personality disorder: Effects on coercion and length of stay
Authors: Dinsenbacher Lisa L. , Imfeld Lukas , Helfenstein Fabrice , Moeller Julian , Lang Undine E. , Huber Christian G. 
Published: September 2024

Background: Acute crises in patients with personality disorders (PD) are often accompanied by suicidal and self-harming behavior. Their management is challenging, as both coercive measures and prolonged inpatient-treatment are known to be counterproductive. Only in crises that cannot be controlled by outpatient means, inpatient treatment is to be taken into account. This treatment should be time-limited and not involve coercion. Aims: The aim of this study was to assess if the introduction of a specialized crisis intervention track is associated with a reduction of coercive measures as well as a shorter in-hospital stay in PD patients. Methods: In this 8-year, hospital-wide, longitudinal, observational study, we investigated the frequency of coercive measures and the median length of in-hospital stay in 1,752 inpatient-cases with PD admitted to the Adult Psychiatry, UPK, Basel, Switzerland, between 01.01.2012 and 31.12.2019. By means of an interrupted-time-series analysis, we compared the period before and after the implementation of a specialized crisis intervention track for PD patients. Results: Our data show a significant decrease in the median length of in-hospital stay and no significant reduction in the incidence rate of coercion among PD patients after the intervention. The latter is likely due to a floor effect, since there was a significant decrease in coercive measures over the entire observation period, already reaching very low rates before the intervention. Conclusions: Our study underlines the clinical importance of specialized short-term crisis management in PD, which comes along with shorter lengths of in-hospital stays and a stable low rate of coercive measure.
Supporting movement and physical activity in people with psychosis: A qualitative exploration of the carer perspective
Authors: Diamond Rowan , Waite Felicity , Boylan Anne-Marie , Hicks Alice , Kabir Thomas , Shiers David , Freeman Daniel 
Published: September 2024

Background: The need to increase exercise and decrease sedentary behaviour in people diagnosed with psychosis is well-recognised. Aims: We set out to explore caregivers’ perspectives on what supports and prevents physical activity, and how to use carers’ support most effectively. Method: Fourteen caregivers of people diagnosed with psychosis were interviewed. Data were analysed using reflexive thematic analysis, in collaboration with caregivers. Results: Four themes were developed, the first flagging the importance of physical activity, then the others calling for action: (a) Physical inactivity matters: carers are keen to support efforts to increase physical activity in their family or friends because of the enormous impact physical inactivity has on patients, and consequently on carers themselves, such as social isolation and reduction in their own activity. (b) Tell us: without being well-informed about how to help, carers can feel like they are powerless to stop a ‘slow suicide’ or ‘decline’ in patients. (c) Listen to us: through knowing their family and friends well, carers are able to identify important changes in patients and identify successful motivators for them, but these insights can feel uninvited. (d) Ask us: being invited to support activity as a partner in a patients’ care is desirable but having offers of help rejected can “demotivate the motivator.” Conclusions: Caregivers described strong motivation to help patients to be more physically active but can feel that their support is overlooked and under-used by services. Clinical recommendations for carer involvement in physical activity interventions are offered.