bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive characterization and comparison of aroma profiles of rambutan seed oils using GC-MS and GC-IMS combined with chemometrics
Authors: Zhou Yanchi , Cui Jingtao , Wei Qiaozhu , Wu Long , Li Tian , Zhang Weimin 
Published: October 2024

BackgroundAroma significantly influences the quality of rambutan seed oil. Nonetheless, few studies have examined the volatile composition of rambutan seed oil. Thus, there is a need for a comprehensive characterization of the aroma profile of rambutan seed oil.MethodsThis study systematically investigated and compared the aroma characteristics of three types (BR-4, BR-5 and BR-7) of rambutan seed oils using HS-SPME-GC-MS and HS-GC-IMS techniques, augmented by chemometric modeling.ResultsGC-MS identified 135 volatile compounds, primarily hydrocarbons and esters, while GC-IMS characterized 35 compounds, mainly aldehydes and alcohols. Multivariate statistical analyses revealed significant differences in the aroma profiles among the oil samples. BR-5 exhibited the highest levels of aldehydes and hydrocarbons, whereas BR-7 demonstrated the highest content of esters and ketones. 21 and 15 differentially volatile compounds were extracted from the datasets obtained via GC-MS and GC-IMS. These compounds primarily comprised esters (floral and fruity) and aldehydes (green and fatty), interacting to create the distinctive aroma profiles of the three rambutan seed oils.ConclusionThis study provides theoretical support for evaluating the flavor characteristics and utilization potential of rambutan seed oil.
Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level
Authors: Hakkak Reza , Korourian Soheila , Li Wei , Spray Beverly , Twaddle Nathan C. , Randolph Christopher E. , Børsheim Elisabet , Robeson II Michael S. 
Published: October 2024

IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is a major public health concern that is exacerbated by the obesity pandemic. Dietary interventions have the potential to alleviate obesity-associated MASLD through variable mechanisms, including optimizing the gut microbiota. Previously, we reported that soy protein concentrate (SPC) with low or high levels of isoflavone (LIF or HIF) protected young obese Zucker rats from developing liver steatosis. The current study was designed to test whether SPC-LIF and SPC-HIF diets would reverse liver steatosis and alter fecal microbial composition in adult obese Zucker rats with existing steatosis.MethodsSix-week-old male obese Zucker rats (n = 26) were fed a casein control diet (CAS) for 8 weeks and 7 rats were randomly selected and sacrificed to confirm liver steatosis. The remaining rats were randomly assigned to receive CAS, SPC-LIF, or SPC-HIF diet (n = 6–7/group) for an additional 10 weeks.ResultsCompared to CAS diet, feeding SPC-LIF and SPC-HIF diets resulted in significantly lower liver weight, liver steatosis score, and liver microvesicular score (p &lt; 0.05), but did not lead to difference in body weight, liver macrovesicular score, serum ALT, or serum AST. Isoflavone levels (e.g., LIF vs. HIF) did not affect any of these measurements except in the SPC-HIF group, which had an additional decrease in liver weight (p &lt; 0.05) compared to the SPC-LIF group. The SPC-HIF group also had significantly higher levels of the aglycone forms of daidzein, genistein, and equol as well as the total levels of daidzein, genistein, and equol compared to SPC-LIF or CAS diet fed rats (p &lt; 0.05). The distribution of microbial communities based on measures of beta diversity of both SPC-LIF and SPC-HIF groups were significantly different to that of the CAS group (p ≤ 0.005). Alpha-diversity did not differ between any of the groups.ConclusionTaken together, dietary soy protein can reverse liver steatosis in adult Zucker rats, and the reversal of steatosis is accompanied by alterations in gut microbial composition.
Prognostic significance of systemic pan-immune-inflammation value in locally advanced cervical cancer
Authors: Yan Shu , Gong Xin , Liu Rui , Jia Xiaojing 
Published: October 2024

ObjectiveThis study investigates the significance of systemic pan-immune inflammation value (PIV) prior to concurrent chemoradiotherapy (CCRT) in predicting the therapeutic efficacy as well as prognosis of patients with locally advanced cervical squamous cell carcinoma.MethodsA retrospective analysis was conducted on the clinical data of 847 patients with locally advanced cervical cancer (LACC) treated at the Second Hospital of Jilin University between 2016 and 2020. All patients underwent radical CCRT, including platinum-based sensitizing chemotherapy. The PIV was measured as given by: (platelet count × neutrophil count × monocyte count)/lymphocyte count. Logistic regression analysis was utilized to study the effect of PIV on therapeutic response in LACC patients and Kaplan–Meier survival together with Cox proportional hazard model to assess its impact on prognosis.ResultsWith the therapeutic effect as the endpoint, the optimal cutoff of PIV (356.0099) was signified via the receiver operating characteristics curve, and patients were grouped and compared based on this value. PIV was determined as an independent predictor of the therapeutic effect in CCRT for LACC (hazard ratio (HR) 1.696, 95% confidence interval (CI) 1.111–2.590). PIV was also an independent predictor of overall survival (OS) (HR 0.540, 95% CI 0.409–0.713, p&lt;0.001) as well as disease-free survival (DFS) (HR 0.680, 95% CI 0.528–0.876, p=0.003). Compared to the low-PIV group, it was noted that individuals with a high PIV exhibited a poorer therapeutic effect and shorter OS and DFS.ConclusionPatients with LACC and high PIV had poorer therapeutic outcomes and shorter OS and DFS. Our results may provide PIV as a new prognostic biomarker for LACC, if future prospective studies with large patient numbers support our findings.
Environmental therapy: interface design strategies for color graphics to assist navigational tasks in patients with visuospatial disorders through an analytic hierarchy process based on CIE color perception
Authors: Li Weicong , Ma Shangbing , Liu Yueling , Lin Haopai , Lv Huabin , Shi Wenwen , Ao Jinghui 
Published: October 2024

IntroductionEnvironmental therapy theory has been applied in the research of disease prevention, and the effectiveness of using color and graphic designs to assist patients with spatial orientation has been confirmed. Visual-spatial impairments are common symptoms associated with cognitive decline. However, the interaction and driving factors between these impairments and spatial color and graphic designs remain unclear.MethodsThis paper first discusses the correlation between the characteristics of visual-spatial impairments and environmental factors and then investigates the color preferences of such patients based on the CIE 1976 color system and the Analytic Hierarchy Process (AHP). Subsequently, the paper explores spatial design strategies conducive to spatial orientation from the perspective of adaptability to pathological characteristics, utilizing case study analysis.Results(1) Pathological characteristics of visual-spatial impairments (such as difficulties in spatial orientation and spatial neglect) are related to environmental factors; (2) Emotional attachment factors play a key role in patients’ perception of satisfaction with environmental colors; (3) Color associations have the potential to strengthen spatial memory. Additionally, interface designs with high luminance, low saturation, and clear color differentiation facilitate patients’ recognition of space.DiscussionThis paper posits that spatial interface design is a feasible approach to assist with spatial orientation, and it achieves this through a mediating process that progresses from influencing visual stimuli to cognitive memory and then to behavioral orientation. The article provides insights into the operational feasibility of this method.
Interconnected factors in EFL engagement: classroom climate, growth mindset, and achievement goals
Authors: Ma Weiran , Yang Weian , Bu Qinggang 
Published: October 2024

IntroductionThis study explores the relationships among classroom climate, growth mindset, achievement goal orientation, and student engagement in the context of English as a foreign language (EFL) education in China. The study aims to understand how these factors interact to influence student engagement and motivation in EFL learning.MethodsData were collected through a questionnaire administered to 587 Chinese undergraduate EFL students. The questionnaire assessed students’ perceptions of classroom climate, growth mindset, achievement goal orientation, and engagement. Structural equation modeling (SEM) was utilized to examine the relationships among these variables.ResultsThe SEM analysis revealed significant positive correlations among classroom climate, growth mindset, achievement goal orientation, and student engagement. Both classroom climate and growth mindset were found to directly and positively predict student engagement. Additionally, achievement goal orientation mediated the relationships between both classroom climate and student engagement, and between growth mindset and student engagement.DiscussionThe findings underscore the interconnectedness of classroom climate, growth mindset, and achievement goal orientation in shaping student engagement in EFL education. These results suggest that fostering a positive classroom climate and promoting mastery-oriented goals can enhance student motivation and contribute to more effective language acquisition. Practical implications for EFL educators are also discussed.
The introduction of the concept of anxiety into China: a thematic historical study
Authors: Miao Peng 
Published: October 2024

IntroductionThis article presents a thematic historical study on the introduction of “anxiety” to modern China. Based on seminal research conducted previously by European scholars on histories of psychological and psychiatric concepts, this article reviews the itinerary of “anxiety” to China by using multiple types of textual evidence. Alongside a detailed description of how “anxiety” was translated and introduced, a comparison between the notions of “anxiety” in Traditional Chinese Medicine (TCM) and Western psychoanalytic approaches was made. The processes of how “depression” and “anxiety” were introduced to China were also compared.Materials and methodsThree types of textual evidence were meticulously analyzed. First, lexicographical works published since the 19th century were examined to trace the initial introduction and observe the standardized translation of “anxiety” in Chinese. Second, newspaper and periodical articles were analyzed to understand how knowledge of “anxiety” was communicated to the general public. Third, the evolution of psychological and psychiatric terminologies was observed through medical books.ResultsIt was found that “anxiety” was initially translated into various Chinese terms, with “jiaolyu” eventually emerging as the standardized term after 1949. The textual evidence showed that “anxiety” began to be acknowledged as a disease concept in the early 20th century, though it was not formally recognized as a diagnostic category until the late 20th century. This article also highlights the differences between the Western psychoanalytic view on anxiety and the Chinese folk conception of it.Discussion and conclusionsIt was observed that the introduction processes of depression and anxiety to China were similar, though their conceptual histories in the West showed much difference. The fading of neurasthenia marked a new era of psychiatric development in China, characterized by an enhanced specificity in the classification of mental disorders, which was never observed in the discourse about “xin feng,” a corresponding TCM notion of “anxiety.” The article also underscores the need for further exploration of corresponding TCM concepts of “anxiety” and the assimilation of Western psychiatric concepts in China.
Being blind (or not) to scenarios used in sacrificial dilemmas: the influence of factual and contextual information on moral responses
Authors: Carron Robin , Brigaud Emmanuelle , Anders Royce , Blanc Nathalie 
Published: October 2024

IntroductionTraditionally, human morality has been largely studied with classical sacrificial dilemmas. A way to advance current understandings of moral judgment and decision-making may involve testing the impact of contexts that are made available to individuals presented with these archetypal dilemmas. This preliminary study focused on assessing whether the availability of factual and contextual information delivered through classical scenarios would change moral responses.MethodA total of 334 participants were presented with sacrificial dilemmas either with a scenario or without a scenario before performing two moral tasks: one consisted in moral judgment (e.g., is it acceptable to sacrifice one person to save five?) and one was related to choice of action (e.g., would you sacrifice one person to save five?). In the condition with a scenario, participants were presented with a story describing the dilemma, its protagonists, their roles, the location and some background details of the situation, before answering to the two moral tasks. In the condition without a scenario, participants were only asked to perform the two moral tasks without any additional contextual elements usually provided by the scenario. Participants’ emotions were also measured before and after completing the two moral tasks.ResultsThe results indicated that the presence of a scenario did not affect moral judgments. However, the presence of a scenario significantly increased utilitarian action choices (i.e., sacrificing one person in the interest of saving a greater number) and this effect was partially mediated by an increase in the perceived plausibility of the sacrificial action. Regarding emotional reaction to dilemmas, no differences were observed between the two conditions, suggesting that emotions are mainly based on the two moral tasks.DiscussionThese findings underscore the value of carefully considering the role of factual and contextual information provided by the scenarios in moral dilemmas.
Equity evaluation of intensive care unit admission based on comorbidity in hospitalized patients with COVID-19: a cross-sectional analysis
Authors: Zhu Yang-Jie , Wang Jia-Yue , Wu Chen-Nan , Yu Bo-Yang , Liu Tong-Tong , Liu Yuan , Zhang Lu-Lu 
Published: October 2024

BackgroundIntensive care unit (ICU) beds played a crucial role in reducing mortality rates of patients with severe COVID-19. The surge in the number of patients led to a shortage of ICU beds, which may have exacerbated inequity of healthcare utilization. However, most attention has been focused on the horizontal equity in healthcare utilization, where individuals with the same needs receive the same services. Vertical equity, where individuals with higher needs receive more healthcare is often neglected, which might overestimate the equity. This study analyzes the vertical equity of ICU utilization among hospitalized patients with COVID-19.MethodsIn total, 18,547 hospitalized patients with COVID-19 in Maryland in 2020 were enrolled in this cross-sectional study. Logistic regression analysis was conducted to determine the independent factors affecting ICU utilization, and the Shapley value decomposition approach was implemented to assess the contribution of the independent variables to disparities in ICU admission. A concentration curve and concentration index were used to assess the vertical equity in healthcare utilization.ResultsICU utilization by patients with COVID-19 was significantly affected by Charlson Comorbidity Index (CCI), with odds ratios (OR) 1.09 [95% confidence intervals (CI): 1.07–1.10; p &lt; 0.001] in univariable analysis and 1.11 (95% CI: 1.09–1.13; p &lt; 0.001) in multivariable regression analysis. The most important contributors were household income (32.27%) and the CCI (22.89%) in the Shapley value decomposition analysis. The concentration curve was below the line of equity, and the concentration index was 0.094 (95% CI: 0.076–0.111; p &lt; 0.001), indicating that ICU utilization was concentrated among patients with a high CCI. These results were robust for all subgroup analyses.ConclusionAmong 18,547 hospitalized patients with COVID-19 in Maryland in 2020, ICU utilization was significantly affected by comorbid conditions. The concentration curve and concentration index also indicated that ICU utilization was more concentrated in patients with a higher CCI. The results was consistent with the principle of vertical equity, whereby healthcare resources are more concentrated on COVID-19 patients with higher health needs.
How does psychosocial safety climate affect safety behavior in the construction industry? A cross-level analysis
Authors: Zhao Wei , Li Shuquan 
Published: October 2024

IntroductionThe unsafe work of construction workers directly contributes to frequent accidents in workplaces. However, the factors influencing the safety behavior of Chinese construction workers are not yet clear.MethodsData from 381 construction workers were analyzed to test our hypotheses.This study aimed to investigate the impact of psychosocial safety climate (PSC) on safety behavior through a cross-level model, focusing on the mediating role of psychological resilience and the moderating effect of safety-related stress.ResultsThe results indicated that (1) PSC was positively associated with psychological resilience and safety behavior; (2) psychological resilience mediated the relationship between PSC and safety behavior; (3) the link between PSC and safety behavior was negatively influenced by safety-related stress; and (4) all three sub-dimensions of safety-related stress moderated the effect of PSC on safety participation.DiscussionThese findings elucidate the mechanisms underlying the connection between PSC, psychological resilience, safety-related stress, and safety behavior from a multi-level perspective. Additionally, strategies for enhancing the safety behavior of construction workers were discussed.
Comparative study of CT-guided radiofrequency and alcohol ablation in the treatment of primary hyperhidrosis
Authors: Yu Yaoping , Cui Jie , Zhang Yu , Feng Lei , Wang Lijun 
Published: October 2024

ObjectiveThis study compared the efficacy and complications of percutaneous radiofrequency ablation with anhydrous alcohol ablation of sympathetic nerves in treating hyperhidrosis of the head and palms.MethodsA retrospective analysis was conducted on 54 patients with primary hyperhidrosis in our department from June 2018 to June 2021, divided into a radiofrequency ablation group (30 cases) and an anhydrous alcohol ablation group (24 cases). Treatment outcomes were compared by analyzing the number of CT scans, effectiveness, and complications.ResultsIn the radiofrequency group, symptoms of bilateral hyperhidrosis significantly improved in 24 patients, with an 80% postoperative satisfaction rate. In the alcohol ablation group, symptoms significantly improved in 19 patients postoperatively, with a 79.2% satisfaction rate. There was no statistically significant difference in effectiveness or complications between the two groups (all P &gt; 0.05). The number of CT scans in the radiofrequency group was 4.60 ± 0.56 and 6.08 ± 0.28 in the alcohol group, showing a statistically significant difference (P &lt; 0.05).ConclusionThis study concluded that both percutaneous radiofrequency ablation and alcohol ablation are effective methods for hyperhidrosis treatment, with similar effectiveness and complication rates, but the radiofrequency ablation group required fewer CT scans.
Leguminous Green Manure Intercropping Promotes Soil Health in a Citrus (Citrus reticulata) Orchard
Authors: Xie Yuxin , Jing Yulin , Wang Yajie , Zheng Rongchun , Xu Qiurui , Sun Zhenyu , Duan Tingyu 
Published: October 2024

The intercropping of green manure is an important and sustainable production method in citrus orchards (Citrus reticulata). However, few studies focus on the impact of annual and perennial green manure on soil health, particularly soil microbiome and properties in acid soil. Our research objective was to explore the potential effects on soil health by intercropping with annual and perennial leguminous green manures in acid soil citrus orchards of southwestern China. The leguminous green manures used were alfalfa (Medicago sativa) and hairy vetch (Vicia villosa). The results showed that intercropping with green manure increased the total nitrogen, nitrate nitrogen, and available phosphorous in the soil by 48.67~74.67%, 50.00~96.67%, and 44.48~45.04%, respectively. Intercropping with alfalfa significantly increased the activity of soil sucrase 63.75%, and intercropping with hairy vetch increased the activity of β-1,4-glucosidase 44.38% in the soil compared to the monoculture treatment. Intercropping hairy vetch and alfalfa altered the diversity and composition of the soil microbial community and enriched the soil with beneficial fungi and bacteria, including Mortierella and Streptomyces. The richness increased by 58.72% and 17.90% in alfalfa intercropping treatment. In conclusion, intercropping leguminous green manure improved the nutrients and activity of the enzymes in the soil and enriched the antagonistic microbiome in the soil, promoting soil health in the citrus orchard.
Impact of Exogenous Lactiplantibacillus plantarum on the Gut Microbiome of Hematopoietic Stem Cell Transplantation Patients Colonized by Multidrug-Resistant Bacteria: An Observational Study
Authors: Moraes Bruna D. G. C. , Martins Roberta C. R. , Fonseca Joyce Vanessa da Silva , Franco Lucas A. M. , Pereira Gaspar C. O. , Bartelli Thais F. , Cortes Marina F. , Scaccia Nazareno , Santos Carolina F. , Musqueira Priscila T. , Otuyama Leonardo J. , Pylro Victor S. , Mariano Livia , Rocha Vanderson , Witkin Steven S. , Sabino Ester , Guimaraes Thais , Costa Silvia Figueiredo 
Published: October 2024

Background: Lactiplantibacillus plantarum can inhibit the growth of multidrug-resistant organisms (MDROs) and modulate the gut microbiome. However, data on hematopoietic stem cell transplantation (HSCT) are scarce. Aim: In an observational study, we assessed the impact of L. plantarum on the modulation of the gut microbiome in HSCT patients colonized by MDROs. Methods: Participants were allocated to an intervention group (IG = 22) who received capsules of L. plantarum (5 × 109 CFU) twice per day until the onset of neutropenia or a control group (CG = 20). The V4 region of the 16S bacterial rRNA gene was sequenced in 87 stool samples from a subset of 33 patients (IG = 20 and CG = 13). The Phylogenetic Investigation of Communities by Reconstruction of Unobserved States (PICRUSt2) program was used to predict metagenome functions. Results: L. plantarum demonstrated an average 86% (±11%) drug-target engagement at 43 (±29) days of consumption and was deemed safe, well-tolerated, and associated with an increase in the abundance of the Lactobacillales (p < 0.05). A significant increase in Lactococcus and a reduction in Turicibacter (p < 0.05) were identified on the second week of L. plantarum use. Although Enterococcus abundance had a greater rise in the CG (p = 0.07), there were no significant differences concerning the Gram-negative MDROs. No serious adverse effects were reported in the IG. We observed a greater, non-significant pyruvate fermentation to propanoate I (p = 0.193) relative abundance in the IG compared with the CG. L. plantarum use was safe and tolerable by HSCT patients. Conclusions: While L. plantarum is safe and may impact Enterococcus and Turicibacter abundance, it showed no impact on Gram-negative MDRO abundance in HSCT patients.