bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Magnet Status With Hospitalization Outcomes for Ischemic Stroke Patients
Authors: Bekelis Kimon , Missios Symeon , MacKenzie Todd A. 
Published: April 2017

Background
It is not clear whether Magnet recognition by the American Nurses Credentialing Center (nursing excellence program) is associated with improved patient outcomes. We investigated whether hospitalization in a Magnet hospital is associated with improved outcomes for patients with ischemic stroke.

Methods and Results

We performed a cohort study of patients with ischemic stroke from 2009 to 2013, who were registered in the New York Statewide Planning and Research Cooperative System database. Propensity‐score‐adjusted multivariable regression models were used to adjust for known confounders, with mixed effects methods to control for clustering at the facility level. An instrumental variable analysis was used to control for unmeasured confounding and simulate the effect of a randomized trial. During the study period, 176 557 patients were admitted for ischemic stroke, and met the inclusion criteria. Of these, 32 092 (18.2%) were hospitalized in Magnet hospitals, and 144 465 (81.8%) in non‐Magnet institutions. Instrumental variable analysis demonstrated that hospitalization in Magnet hospitals was associated with lower case‐fatality (adjusted difference, −23.9%; 95%
CI
, −29.0% to −18.7%), length of stay (adjusted difference, −0.4; 95%
CI
, −0.8 to −0.1), and rate of discharge to a facility (adjusted difference, −16.5%; 95%
CI
, −20.0% to −13.0%) in comparison to non‐Magnet hospitals. The same associations were present in propensity‐score‐adjusted mixed effects models.

Conclusions
Using a comprehensive all‐payer cohort of patients with ischemic stroke in New York State, we identified an association of treatment in Magnet hospitals with lower case‐fatality, discharge to a facility, and length of stay. Further research into the factors contributing to the superiority of Magnet hospitals in stroke care is warranted.
A variational approach to nonlinear electro-magneto-elasticity: Convexity conditions and existence theorems
Authors: Šilhavý Miroslav 
Published: April 2017

Electro- or magneto-sensitive elastomers are smart materials whose mechanical properties change instantly by the application of an electric or magnetic field. This paper analyses the convexity conditions (quasiconvexity, polyconvexity, ellipticity) of the free energy of such materials. These conditions are treated within the framework of the general A-quasiconvexity theory for the constraints [Formula: see text] where F is the deformation gradient, d is the electric displacement and b is the magnetic induction. If the energy depends separately only on F, or on d, or on b, the A-quasiconvexity reduces, respectively, to Morrey’s quasiconvexity, polyconvexity and ellipticity conditions or to convexity in d or in b. In the present case, the simultaneous occurrence of F, d and b leads to the cross-phenomena: mechanic–electric, mechanic–magnetic and electro–magnetic. The main results of the paper are as follows. In dimension 3 there are 32 linearly independent scalar A-affine functions (and 15 in dimension 2) corresponding to the constraints (*). Therefore, an energy function ψ ( F, d, b) is A-polyconvex if and only if it is of the form [Formula: see text] where Φ is a convex function (of 31 scalar variables). Apart from the expected terms F, cof F, det F, d and b, we have the cross-effect terms Fd, Fb (and in dimension 2 also d × b). An existence theorem is proved for a state of minimum energy for a system consisting of an A-polyconvex electro-magneto-elastic solid plus the vacuum electromagnetic field outside the body.
Effectiveness of Sub-Tenon’s Bupivacaine Liposome Injectable Suspension for Postoperative Pain Control After Radioactive Plaque Placement for Ciliary Body and Choroidal Melanomas
Authors: Neely David C. , Mason Lauren , Crosson Jason N. , Bray Kevin J. , McGwin Gerald G. , Mason John O. 
Published: April 2017

Purpose: To examine the difference in pain control and systemic pain medication usage with sub-Tenon’s bupivacaine versus bupivacaine liposome injectable suspension (BLIS) following radioactive plaque placement for choroidal and ciliary body melanomas. Methods: Retrospective chart review reporting postoperative nurse and physician pain scores, postoperative systemic pain medication usage, and telephone pain survey conducted at a single university institution from January 2016 to October 2016. Results: There were 9 (9 eyes) patients studied who underwent sub-Tenon’s bupivacaine injection and 9 (9 eyes) patients who underwent sub-Tenon’s BLIS. There were no statistically significant differences on postoperative days 1 to 3 between nurse pain scores, physician pain scores, vision, and average intraocular pressure. The difference in postoperative days 1 and 2 hydrocodone/acetaminophen usage was statistically significant (average pills per day on postoperative day 1 for bupivacaine only 0.22 versus 2.33 for BLIS, P value .0032; and postoperative day 2 for bupivacaine only 0.00 versus 1.00 for BLIS, P value .0289). There were no other statistically significant differences in postoperative systemic pain medication usage. There were no statistically significant differences in telephone pain survey. Conclusion: There was no clinically meaningful difference in postoperative nurse and physician pain scores, postoperative systemic pain medication usage, and telephone pain survey between sub-Tenon’s bupivacaine versus BLIS following radioactive plaque placement for choroidal and ciliary body melanomas.
Norilskite, (Pd,Ag)7Pb4, a new mineral from Noril'sk-Talnakh deposit, Russia
Authors: Vymazalová A. , Laufek F. , Sluzhenikin S. F. , Stanley C. J. 
Published: April 2017

AbstractNorilskite, (Pd,Ag)7Pb4 is a new platinum-group mineral discovered in the Mayak mine of the Talnakh deposit, Russia. It forms anhedral grains in aggregates (up to ∼400 μm) with polarite, zvyagintsevite, Pd-rich tetra-auricupride, Pd-Pt bearing auricupride,Ag-Au alloys, (Pb,As,Sb) bearing atokite, mayakite, Bi-Pb-rich kotulskite and sperrylite in pentlandite, cubanite and talnakhite. Norilskite is brittle, has a metallic lustre and a grey streak. Values of VHN20 fall between 296 and 342 kg mm–2, with a mean valueof 310 kg mm–2, corresponding to a Mohs hardness of ∼4. In plane-polarized light, norilskite is orange-brownish pink, has moderate to strong bireflectance, orange-pink to greyish-pink pleochroism, and strong anisotropy; it exhibits no internal reflections. Reflectancevalues of norilskite in air (Ro, Re' in %) are: 51.1, 48.8 at 470 nm, 56.8, 52.2 at 546 nm, 59.9, 53.5 at 589 nm and 64.7, 55.5 at 650 nm. Sixteen electronmicroprobe analyses of natural norilskite gave an average composition: Pd 44.33, Ag 2.68, Bi 0.33 and Pb 52.34, total99.68 wt.%, corresponding to the empirical formula (Pd6.56Ag0.39)∑6.95(Pb3.97Bi0.03)∑4.00 based on 4 Pb + Bi atoms; the average of eight analyses on synthetic norilskite is: Pd 42.95, Ag 3.87 and Pb 53.51, total 100.33wt.%, corresponding to (Pd6.25Ag0.56)∑6.81Pb4.00. The mineral is trigonal, space group P3121, with a = 8.9656(4), c = 17.2801(8) Å, V = 1202.92(9) Å3 and Z = 6. The crystalstructure was solved and refined from the powder X-ray diffraction data of synthetic (Pd,Ag)7Pb4. Norilskite crystallizes in the Ni13Ga3Ge6 structure type, related to nickeline. The strongest lines in the powder X-ray diffraction patternof synthetic norilskite [d in Å (I) (hkl)] are: 3.2201(29)(023,203), 2.3130(91)(026,206), 2.2414(100)(220), 1.6098(28)(046,406), 1.3076(38)(246,462), 1.2942(18)(600), 1.2115(37)(22.12,12.13), 0.9626(44) (06.12,60.12). The mineral is named for the locality, the Noril'sk district in Russia.
Cord Blood Adipocyte Fatty Acid–Binding Protein Levels Correlate With Gestational Age and Birth Weight in Neonates
Authors: Joung Kyoung Eun , Cataltepe Sule Umit , Michael Zoe , Christou Helen , Mantzoros Christos S. 
Published: April 2017

AbstractContext:Infants born small for gestational age (SGA) have increased risk for obesity and metabolic syndrome, but the underlying mechanisms are not fully elucidated. Adipocyte fatty acid–binding protein (AFABP) is an adipokine that has been implicated in modulation of insulin sensitivity and lipid metabolism. Higher plasma AFABP levels are associated with increased risk of metabolic syndrome and cardiovascular morbidity in adults. Alterations in AFABP levels during fetal growth have not been characterized.Objective:To examine AFABP levels in neonatal cord blood in relation to gestational age and birth weight.Design:A cross-sectional study of 361 neonates born at a tertiary academic center.Outcome Measures:Plasma AFABP levels were measured by enzyme-linked immunosorbent assay. For comparison, venous samples from 26 adults were analyzed.Results:AFABP levels were higher in neonates compared with adults (P &lt; 0.01). Preterm infants had higher AFABP levels [48.2 (31.2 to 73.3) ng/mL] compared with full-term infants [35.8 (25.1 to 51.5)] ng/mL, P &lt; 0.01). There was a negative correlation between AFABP and gestational age (r = 0.28, P = 0.02). Among full-term infants, AFABP levels in SGA infants were lower [28.6 (24.2 to 37.3) ng/mL], compared with appropriate for gestational age [36.1 (25.5 to 50.4) ng/mL] and large for gestational age infants [45.0 (24.6 to 62.4) ng/mL, P &lt; 0.05].Conclusions:These associations may reflect the higher metabolic activity during fetal development. AFABP may also be involved in fetal growth and the association between SGA status and obesity and metabolic syndrome in later life.
Early Prenatal Phthalate Exposure, Sex Steroid Hormones, and Birth Outcomes
Authors: Sathyanarayana Sheela , Butts Samantha , Wang Christina , Barrett Emily , Nguyen Ruby , Schwartz Stephen M. , Haaland Wren , Swan Shanna H. ,   the TIDES Team
Published: April 2017

Abstract

Context:
Adequate sex steroid hormone concentrations are essential for normal fetal genital development in early pregnancy. Our previous study demonstrated an inverse relationship between third-trimester di-2-ethyl hexyl phthalate exposure and total testosterone (TT) concentrations. Here, we examine early-pregnancy phthalates, sex steroid hormone concentrations, and newborn reproductive outcomes.

Design:
We examined associations between urinary phthalate metabolite concentrations in early pregnancy and serum free testosterone (FT), TT, estrone (E1), and estradiol (E2) in 591 woman/infant dyads in The Infant Development and Environment Study; we also examined relationships between hormones and newborn genital outcomes using multiple regression models with covariate adjustment.

Results:
E1 and E2 concentrations were 15% to 30% higher in relation to 1-unit increases in log monoisobutyl phthalate (MiBP), mono-2-ethyl hexyl phthalate, and mono-2-ethyl-5-oxy-hexyl phthalate concentrations, and E2 was 15% higher in relation to increased log monobenzyl phthalate (MBzP). FT concentrations were 12% lower in relation to 1-unit increases in log mono(carboxynonyl) phthalate (MCNP) and mono-2-ethyl-5-carboxypentyl phthalate concentrations. Higher maternal FT was associated with a 25% lower prevalence of having a male genital abnormality at birth.

Conclusions:
The positive relationships between MiBP, MBzP, and DEHP metabolites and E1/E2 are unique and suggest a positive estrogenic effect in early pregnancy. The inverse relationship between MCNP and DEHP metabolites and serum FT supports previous work examining phthalate/testosterone relationships later in pregnancy. Higher FT in relation to a 25% lower prevalence of male genital abnormalities confirms the importance of testosterone in early fetal development.
Rapid Onset of Diabetic Ketoacidosis After SGLT2 Inhibition in a Patient With Unrecognized Acromegaly
Authors: Quarella Marino , Walser Daniel , Brändle Michael , Fournier Jean-Yves , Bilz Stefan 
Published: April 2017

Abstract

Context:
Diabetic ketoacidosis has been described as a rare complication of acromegaly and may be observed in 1% of affected patients. The well-described direct lipolytic effect of growth hormone results in increased availability of free fatty acids (FFAs) for hepatic ketogenesis and is an important pathogenic event. More recently, ketoacidosis has been identified as an important complication of sodium-glucose-transport-protein 2 inhibitors (SGLT2i). Increased pancreatic glucagon secretion, impaired renal ketone body clearance, and an increase in FFA concentrations secondary to decreased insulin concentrations are likely precipitating factors.

Case Description:
We report a case of rapid-onset severe ketoacidosis within 2 days after adding empagliflozin to metformin, sitagliptin, and gliclazide in a presumably type 2 diabetic patient with unrecognized acromegaly and chronic hyperglycemia. Transsphenoidal resection of the growth-hormone secreting macroadenoma restored normal growth-hormone and insulinlike growth factor 1 concentrations and the diabetes was well controlled thereafter.

Conclusion:
We hypothesize that SGLT2i, through their intrinsic effects on ketone body metabolism, may possibly precipitate ketoacidosis in patients with active acromegaly and diabetes mellitus.
PTK7 localization and protein stability is affected by canonical Wnt ligands
Authors: Berger Hanna , Breuer Marlen , Peradziryi Hanna , Podleschny Martina , Jacob Ralf , Borchers Annette 
Published: April 2017

ABSTRACT
Protein tyrosine kinase 7 (PTK7) is an evolutionarily conserved transmembrane receptor with important roles in embryonic development and disease. Originally identified as a gene upregulated in colon cancer, it was later shown to regulate planar cell polarity (PCP) and directional cell movement. PTK7 is a Wnt co-receptor; however, its role in Wnt signaling remains controversial. Here, we find evidence that places PTK7 at the intersection of canonical and non-canonical Wnt signaling pathways. In presence of canonical Wnt ligands PTK7 is subject to caveolin-mediated endocytosis, while it is unaffected by non-canonical Wnt ligands. PTK7 endocytosis is dependent on the presence of the PTK7 co-receptor Fz7 (also known as Fzd7) and results in lysosomal degradation of PTK7. As we previously observed that PTK7 activates non-canonical PCP Wnt signaling but inhibits canonical Wnt signaling, our data suggest a mutual inhibition of canonical and PTK7 Wnt signaling. PTK7 likely suppresses canonical Wnt signaling by binding canonical Wnt ligands thereby preventing their interaction with Wnt receptors that would otherwise support canonical Wnt signaling. Conversely, if canonical Wnt proteins interact with the PTK7 receptor, they induce its internalization and degradation.
Catalyst Design of Iron Complexes
Authors: Nagashima Hideo 
Published: April 2017

Abstract
Despite worldwide interest from synthetic chemists, the rational design of catalytically active organoiron species remains problematic. While noble metal catalysis proceeds through diamagnetic low-spin intermediates, iron species are often in the high or intermediate spin states, which are paramagnetic and difficult to analyze. Possible spin change during catalysis also complicates the problem. This report describes two extremes for the catalyst design of iron complexes. One involves diamagnetic 14-electron iron(II) species useful for two-electron chemistry often seen in noble metal catalysis. The disilaferracyclic carbonyl complex 4 is a good catalyst precursor, and shows good catalytic performance for the hydrogenation and hydrosilylation of alkenes, and the hydrosilane reduction of carbonyl compounds. Based on DFT calculations, mechanisms involving σ-CAM (sigma-complex-assisted metathesis) for the hydrogenation and hydrosilane reduction are suggested. Further catalyst design inspired by the success of 4 led to the discovery of iron and cobalt catalyst systems composed of metal carboxylates and isocyanide ligands leading to a practical substitute for industrially useful platinum catalysts for hydrosilylation with hydrosiloxanes. The second approach involves paramagnetic 16-electron iron (II) catalyst species. A series of “(R3TACN)FeX2” complexes were prepared and found to be good catalysts for atom transfer radical polymerization, giving rise to well-controlled polymerization of styrene, methacrylates, and acrylates with high activity. Moreover, the catalyst could be easily removed from the polymer and was reusable. Mechanistic studies of iron-catalyzed cross-coupling reactions in collaboration with Nakamura and Takaya opened a new approach to the catalyst design of unknown spin states by using new analytical methods for paramagnetic species in the solution state.
Quasilinear elliptic equations with critical potentials
Authors: D’Ambrosio Lorenzo , Mitidieri Enzo 
Published: April 2017

Abstract
We study Liouville theorems for problems of the form

div
L

⁡

(

𝒜
⁢

(
x
,
u
,

∇
L

⁡
u

)

)

+

V
⁢

(
x
)

⁢

|
u
|

p
-
2

⁢
u

=

a
⁢

(
x
)

⁢

|
u
|

q
-
1

⁢
u

on
⁢

ℝ
N

$\operatorname{div}_{L}({\mathscr{A}}(x,u,\nabla_{L}u))+V(x)|u|^{p-2}u=a(x)|u|^%
{q-1}u\quad\text{on }{{\mathbb{R}}}^{N}$

in the framework of Carnot groups. Here

𝒜

${{\mathscr{A}}}$

is a vector-valued function satisfying Carathéodory
condition and

∇
L

${\nabla_{L}}$

denotes an horizontal gradient,
V is a given singular potential, a is a measurable scalar function and

q
>

p
-
1

.

${q>p-1.}$

Particular emphasis is given to the case when V is a Hardy or Gagliardo–Nirenberg
potential. The results are new even in the canonical Euclidean setting.
Early closeout of derivatives in the light of corporate income tax
Authors: Karczyński Łukasz 
Published: April 2017

Abstract
Due to financial crisis many entrepreneurs suffered heavy losses on derivatives, mainly currency options and forward contracts. Tax authorities tend to disallow deduction of those losses from the taxable income. Many cases ended up in administrative courts, resulting in judicature controversies on the issue in question. This paper is the third of four in a cycle. The aim of the whole cycle is to analyze deeply these controversies and suggest the proper interpretation of the legal provisions, determining whether the expenses on currency options and forward contracts should or should not be regarded as tax-deductible expenses. The aim of this paper is to determine if the rights from the derivatives are being exercised or waived (as the law provides) in case of their early closeout (which allows the deduction as well). The conducted analysis suggests that early derivative closeout realises in exercising the rights from the derivative (as the law provides), which allows the deduction.
L

p
boundedness of rough bi-parameter Fourier integral operators
Authors: Hong Qing , Lu Guozhen , Zhang Lu 
Published: April 2017

Abstract
In this paper, we will investigate the boundedness of the bi-parameter Fourier integral operators (or FIOs for short) of the following form:

T
⁢

(
f
)

⁢

(
x
)

=

1

(

2
⁢
π

)

2
⁢
n

⁢

∫

ℝ

2
⁢
n

e

i
⁢
φ
⁢

(
x
,
ξ
,
η
)

⋅
a

⁢

(
x
,
ξ
,
η
)

⋅

f
^

⁢

(
ξ
,
η
)

⁢

𝑑

ξ

⁢

𝑑
η

,

T(f\/)(x)=\frac{1}{(2\pi)^{2n}}\int_{\mathbb{R}^{2n}}e^{i\varphi(x,\xi,\eta)}%
\cdot a(x,\xi,\eta)\cdot\widehat{f}(\xi,\eta)\,d\xi\,d\eta,

where

x
=

(

x
1

,

x
2

)

∈

ℝ
n

×

ℝ
n

{x=(x_{1},x_{2})\in\mathbb{R}^{n}\times\mathbb{R}^{n}}

and

ξ
,
η

∈

ℝ
n

∖

{
0
}

{\xi,\eta\in\mathbb{R}^{n}\setminus\{0\}}

,

a
⁢

(
x
,
ξ
,
η
)

∈

L
∞

⁢
B
⁢

S
ρ
m

{a(x,\xi,\eta)\in L^{\infty}BS^{m}_{\rho}}

is the amplitude,
and the phase function is of the form

φ
⁢

(
x
,
ξ
,
η
)

=

φ
1

⁢

(

x
1

,
ξ
)

+

φ
2

⁢

(

x
2

,
η
)

\varphi(x,\xi,\eta)=\varphi_{1}(x_{1},\xi\/)+\varphi_{2}(x_{2},\eta)

, with

φ
1

,

φ
2

∈

L
∞

⁢

Φ
2

⁢

(

ℝ
n

×

ℝ
n

∖

{
0
}

)

\varphi_{1},\varphi_{2}\in L^{\infty}\Phi^{2}(\mathbb{R}^{n}\times\mathbb{R}^{%
n}\setminus\{0\})

, and satisfies a certain rough non-degeneracy condition (see (2.2)).
The study of these operators are motivated by the

L
p

{L^{p}}

estimates for one-parameter FIOs and bi-parameter Fourier multipliers and pseudo-differential operators. We will first define the bi-parameter FIOs and then study the

L
p

{L^{p}}

boundedness of such operators when their phase functions have compact support in frequency variables with certain necessary non-degeneracy conditions. We will then establish the

L
p

{L^{p}}

boundedness of the more general FIOs with amplitude

a
⁢

(
x
,
ξ
,
η
)

∈

L
∞

⁢
B
⁢

S
ρ
m

{a(x,\xi,\eta)\in L^{\infty}BS^{m}_{\rho}}

and non-smooth phase function

φ
⁢

(
x
,
ξ
,
η
)

{\varphi(x,\xi,\eta)}

on x satisfying a rough non-degeneracy condition.
A commonsense assessment of Arrow’s theorem
Authors: Ortona Guido 
Published: April 2017

Abstract
The usual, pessimistic interpretation of Arrow’s General Possibility Theorem (often “Impossibility” in textbooks) is excessive. The impossibility defined by Arrow occurs only in presence of a tie or of a cycle. These cases are rare or very rare, and their presence may be assessed ex post. If they occur it is necessary to resort to a second-best rule, but this two-stage procedure does not induce strategic behavior, nor impeaches the use of the Condorcet rule (in observance of the axioms) in all the others.
The paper conclusions sustain that implementation of modern management systems to government’s public institutions should deal with a different behavior used to know at companies. In this respect, the paper high-lights different aspects between companies and public institutions behavior admitting similarities on organizational structure and internal procedures.
Computing with dynamical systems based on insulator-metal-transition oscillators
Authors: Parihar Abhinav , Shukla Nikhil , Jerry Matthew , Datta Suman , Raychowdhury Arijit 
Published: April 2017

AbstractIn this paper, we review recent work on novel computing paradigms using coupled oscillatory dynamical systems. We explore systems of relaxation oscillators based on linear state transitioning devices, which switch between two discrete states with hysteresis. By harnessing the dynamics of complex, connected systems, we embrace the philosophy of “let physics do the computing” and demonstrate how complex phase and frequency dynamics of such systems can be controlled, programmed, and observed to solve computationally hard problems. Although our discussion in this paper is limited to insulator-to-metallic state transition devices, the general philosophy of such computing paradigms can be translated to other mediums including optical systems. We present the necessary mathematical treatments necessary to understand the time evolution of these systems and demonstrate through recent experimental results the potential of such computational primitives.
Numerical simulations of CO2 sequestration in basaltic rock formations: challenges for optimizing mineral-fluid reactions
Authors: Gysi Alexander P. 
Published: April 2017

Abstract
Numerical simulations were carried out for determining the chemical reactions relevant for the sequestration of CO2 in basaltic rock formations. The mineralogy of natural geological systems consists of silicate minerals such as the phyllosilicates and zeolites that form complex solid solutions. Using the GEMS code package based on Gibbs energy minimization, combined with the new MINES database, we can now simulate the solubility of these multicomponent and multisite mineral solid solutions in basaltic rocks. This study explores the varying effects of CO2 partial pressures, basaltic glass dissolution kinetics and reaction time on the complex chemistry of the overall CO2-water-basalt reaction path. The simulations indicate four reaction progress stages with the competing reactions between smectites (di- and trioctahedral) and Ca-Fe-Mg-carbonates controlling the amount of CO2 mineralized. A better understanding of these key mineral-fluid reactions and improvement of their thermodynamic models is critical for making more acurate predictive calculations. This comprises the basis for extending the simulations to reactive transport models, and for the assessment of the feasibility of long-term CO2 storage in basaltic rock formations.