bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs
Authors: Flahou Bram , Rossi Mirko , Bakker Jaco , Langermans Jan A M , Heuvelman Edwin , Solnick Jay V , Martin Miriam E , O’Rourke Jani , Ngoan Le Duc , Hoa Nguyen Xuan , Nakamura Masahiko , Øverby Anders , Matsui Hidenori , Ota Hiroyoshi , Matsumoto Takehisa , Foss Dennis L , Kopta Laurice A , Omotosho Oladipo , Franciosini Maria Pia , Casagrande Proietti Patrizia , Guo Aizhen , Liu Han , Borilova Gabriela , Bracarense Ana Paula , Lindén Sara K , De Bruyckere Sofie , Zhang Guangzhi , De Witte Chloë , Smet Annemieke , Pasmans Frank , Ducatelle Richard , Corander Jukka , Haesebrouck Freddy 
Published: September 2017

Abstract
Helicobacter suis is the second most prevalent Helicobacter species in the stomach of humans suffering from gastric disease. This bacterium mainly inhabits the stomach of domesticated pigs, in which it causes gastric disease, but it appears to be absent in wild boars. Interestingly, it also colonizes the stomach of asymptomatic rhesus and cynomolgus monkeys. The origin of modern human-, pig- or non-human primate-associated H. suis strains in these respective host populations was hitherto unknown. Here we show that H. suis in pigs possibly originates from non-human primates. Our data suggest that a host jump from macaques to pigs happened between 100 000 and 15 000 years ago and that pig domestication has had a significant impact on the spread of H. suis in the pig population, from where this pathogen occasionally infects humans. Thus, in contrast to our expectations, H. suis appears to have evolved in its main host in a completely different way than its close relative Helicobacter pylori in humans.
Wave propagation through disordered media without backscattering and intensity variations
Authors: Makris Konstantinos G , Brandstötter Andre , Ambichl Philipp , Musslimani Ziad H , Rotter Stefan 
Published: September 2017

AbstractA fundamental manifestation of wave scattering in a disordered medium is the highly complex intensity pattern the waves acquire due to multi-path interference. Here we show that these intensity variations can be entirely suppressed by adding disorder-specific gain and loss components to the medium. The resulting constant-intensity waves in such non-Hermitian scattering landscapes are free of any backscattering and feature perfect transmission through the disorder. An experimental demonstration of these unique wave states is envisioned based on spatially modulated pump beams that can flexibly control the gain and loss components in an active medium.
Modulation of estrogen synthesis and metabolism by phytoestrogensin vitroand the implications for women's health
Authors: van Duursen Majorie B. M. 
Published: September 2017

AbstractPhytoestrogens are increasingly used as dietary supplements due to their suggested health promoting properties, but also by women for breast enhancement and relief of menopausal symptoms. Generally, phytoestrogens are considered to exert estrogenic activity via estrogen receptors (ERs), but they may also affect estrogen synthesis and metabolism locally in breast, endometrial and ovarian tissues. Considering that accurate regulation of local hormone levels is crucial for normal physiology, it is not surprising that interference with hormonal synthesis and metabolism is associated with a wide variety of women's health problems, varying from altered menstrual cycle to hormone-dependent cancers. Yet, studies on phytoestrogens have mainly focused on ER-mediated effects of soy-derived phytoestrogens, with less attention paid to steroid synthesis and metabolism or other phytoestrogens. This review aims to evaluate the potential of phytoestrogens to modulate local estrogen levels and the implications for women's health. For that, an overview is provided of the effects of commonly used phytoestrogens, i.e. 8-prenylnaringenin, biochanin A, daidzein, genistein, naringenin, resveratrol and quercetin, on estrogen synthesizing and metabolizing enzymes in vitro. The potential implications for women's health are assessed by comparing the in vitro effect concentrations with blood concentrations that can be found after intake of these phytoestrogens. Based on this evaluation, it can be concluded that high-dose supplements with phytoestrogens might affect breast and endometrial health or fertility in women via the modulation of steroid hormone levels. However, more data regarding the tissue levels of phytoestrogens and effect data from dedicated, tissue-specific assays are needed for a better understanding of potential risks. At least until more certainty regarding the safety has been established, especially young women would better avoid using supplements containing high doses of phytoestrogens.
Alarm- und Einsatzplanung im Krankenhaus: Vorbereitung auf Großschadenslagen
Authors: Wurmb Thomas , Scholtes Katja , Kolibay Felix , Rechenbach Peer , Vogel Ulrich , Kowalzik Barbara 
Published: September 2017

ZusammenfassungKrankenhäuser spielen bei der Bewältigung von Großschadenslagen oder Katastrophen eine entscheidende Rolle. Dies wurde durch die terroristischen Anschläge und Amoktaten der letzten Jahre in Europa besonders deutlich. Die Anschlagsnacht in Paris vom November 2015 hat eindrücklich gezeigt, welche außerordentlichen Leistungen Krankenhäuser in solchen Fällen erbringen können. Um außergewöhnliche Situationen und Schadenslagen bewältigen zu können, bedarf es seitens der Krankenhäuser einer detaillierten Vorbereitung – der Erstellung eines Krankenhaus-Alarm- und Einsatzplanes. Der hier vorgelegte Artikel beschreibt ausführlich die theoretischen Hintergründe der Alarm- und Einsatzplanung an Krankenhäusern. Darüber hinaus wird anhand eines Beispiels anschaulich gezeigt, wie die konkrete Erstellung eines Einsatzplanes erfolgt.
Improving prediction accuracy of cooling load using EMD, PSR and RBFNN
Authors: Shen Limin , Wen Yuanmei , Li Xiaohong 
Published: September 2017

Abstract
To increase the accuracy for the prediction of cooling load demand, this work presents an EMD (empirical mode decomposition)-PSR (phase space reconstruction) based RBFNN (radial basis function neural networks) method. Firstly, analyzed the chaotic nature of the real cooling load demand, transformed the non-stationary cooling load historical data into several stationary intrinsic mode functions (IMFs) by using EMD. Secondly, compared the RBFNN prediction accuracies of each IMFs and proposed an IMF combining scheme that is combine the lower-frequency components (called IMF4-IMF6 combined) while keep the higher frequency component (IMF1, IMF2, IMF3) and the residual unchanged. Thirdly, reconstruct phase space for each combined components separately, process the highest frequency component (IMF1) by differential method and predict with RBFNN in the reconstructed phase spaces. Real cooling load data of a centralized ice storage cooling systems in Guangzhou are used for simulation. The results show that the proposed hybrid method outperforms the traditional methods.
Amplified summer warming in Europe–West Asia and Northeast Asia after the mid-1990s
Authors: Hong Xiaowei , Lu Riyu , Li Shuanglin 
Published: September 2017

Abstract
Regional temperature changes are a crucial factor in affecting agriculture, ecosystems and societies, which depend greatly on local temperatures. We identify a nonuniform warming pattern in summer around the mid-1990s over the Eurasian continent, with a predominant amplified warming over Europe–West Asia and Northeast Asia but much weaker warming over Central Asia. It is found that the nonuniform warming concurs with both the phase shift of the Atlantic Multi-decadal Oscillation (AMO) and the decadal change in the Silk Road Pattern (SRP), which is an upper-tropospheric teleconnection pattern over the Eurasian continent during summer. We suggest that the AMO may modulate the decadal change in SRP and then induce the zonal asymmetry in temperature changes. Our results have important implications for decadal prediction of regional warming pattern in Eurasia based on the predictable AMO.
Image Fusion Algorithms Using Human Visual System in Transform Domain
Authors: Vadhi Radhika , Kilari Veera Swamy , Samayamantula Srinivas Kumar 
Published: September 2017

Abstract
The endeavor of digital image fusion is to combine the important visual parts from various sources to advance the visibility eminence of the image. The fused image has a more visual quality than any source images. In this paper, the Human Visual System (HVS) weights are used in the transform domain to select appropriate information from various source images and then to attain a fused image. In this process, mainly two steps are involved. First, apply the DWT to the registered source images. Later, identify qualitative sub-bands using HVS weights. Hence, qualitative sub-bands are selected from different sources to form high quality HVS based fused image. The quality of the HVS based fused image is evaluated with general fusion metrics. The results show the superiority among the state-of-the art resolution Transforms (MRT) such as Discrete Wavelet Transform (DWT), Stationary Wavelet Transform (SWT), Contourlet Transform (CT), and Non Sub Sampled Contourlet Transform (NSCT) using maximum selection fusion rule.
Towards generic adiabatic elimination for bipartite open quantum systems
Authors: Azouit R , Chittaro F , Sarlette A , Rouchon P 
Published: September 2017

Abstract
We consider a composite open quantum system consisting of a fast subsystem coupled to a slow one. Using the time scale separation, we develop an adiabatic elimination technique to derive at any order the reduced model describing the slow subsystem. The method, based on an asymptotic expansion and geometric singular perturbation theory, ensures the physical interpretation of the reduced second-order model by giving the reduced dynamics in a Lindblad form and the state reduction in Kraus map form. We give explicit second-order formulas for Hamiltonian or cascade coupling between the two subsystems. These formulas can be used to engineer, via a careful choice of the fast subsystem, the Hamiltonian and Lindbald operators governing the dissipative dynamics of the slow subsystem.
Effects of dapagliflozin on human epicardial adipose tissue: modulation of insulin resistance, inflammatory chemokine production, and differentiation ability
Authors: Díaz-Rodríguez Esther , Agra Rosa M , Fernández Ángel L , Adrio Belén , García-Caballero Tomás , González-Juanatey José R , Eiras Sonia 
Published: September 2017

AbstractAimsIn patients with cardiovascular disease, epicardial adipose tissue (EAT) is characterized by insulin resistance, high pro-inflammatory chemokines, and low differentiation ability. As dapagliflozin reduces body fat and cardiovascular events in diabetic patients, we would like to know its effect on EAT and subcutaneous adipose tissue (SAT).Methods and resultsAdipose samples were obtained from 52 patients undergoing heart surgery. Sodium-glucose cotransporter 2 (SGLT2) expression was determined by real-time polymerase chain reaction (n = 20), western blot, and immunohistochemistry. Fat explants (n = 21) were treated with dapagliflozin and/or insulin and glucose transporters expression measured. Glucose, free fatty acid, and adipokine levels (by array) were measured in the EAT secretomes, which were then tested on human coronary endothelial cells using wound healing assays. Glucose uptake was also measured using the fluorescent glucose analogue (6NBDG) in differentiated stromal vascular cells (SVCs) from the fat pads (n = 11). Finally, dapagliflozin-induced adipocyte differentiation was assessed from the levels of fat droplets (AdipoRed staining) and of perilipin. SGLT2 was expressed in EAT. Dapagliflozin increased glucose uptake (20.95 ± 4.4 mg/dL vs. 12.97 ± 4.1 mg/dL; P < 0.001) and glucose transporter type 4 (2.09 ± 0.3 fold change; P < 0.01) in EAT. Moreover, dapagliflozin reduced the secretion levels of chemokines and benefited wound healing in endothelial cells (0.21 ± 0.05 vs. 0.38 ± 0.08 open wound; P < 0.05). Finally, chronic treatment with dapagliflozin improved the differentiation of SVC, confirmed by AdipoRed staining [539 ± 142 arbitrary units (a.u.) vs. 473 ± 136 a.u.; P < 0.01] and perilipin expression levels (121 ± 10 vs. 84 ± 11 a.u.).ConclusionsDapagliflozin increased glucose uptake, reduced the secretion of pro-inflammatory chemokines (with a beneficial effect on the healing of human coronary artery endothelial cells), and improved the differentiation of EAT cells. These results suggest a new protective pathway for this drug on EAT from patients with cardiovascular disease.
Migrants’ transnational political engagement in Spain and Italy
Authors: Guarnizo Luis Eduardo , Chaudhary Ali R , Sørensen Ninna Nyberg 
Published: September 2017

AbstractInternational migrants’ cross-border political activities challenge singular notions of national citizenship and political belonging. Yet most sociological studies of migrants’ transnational political engagement are based on single national groups in the USA, and limit themselves to examining how assimilation and contexts of reception determine migrants’ propensity to engage with homeland politics—thereby under theorizing the influence of origin countries. This study moves beyond this approach by recognizing the multi-directionality of migration, and testing the applicability of existing theoretical approaches across two different origins and receiving contexts. We compare a sample of Colombian and Dominican migrants in Spain and Italy, analyzing how contexts in countries of origin, as well as migrants’ social networks across borders, interact with assimilation and contexts of reception to determine migrants’ political transnational engagement. Findings reveal migrants’ transnational political engagement in Spain and Italy appears to be a highly selective process dominated by a small minority of well-educated males from high social status in origin. Findings also suggest immigrant incorporation and transnational political engagement form a dialectical relationship operating at different scales that is simultaneously complementary and contradictory. Contextual conditions in origin countries explain observed much of variation in Colombian and Dominican migrants’ transnational political engagement.
The Cost-effectiveness of a Point-of-Care Paper Transaminase Test for Monitoring Treatment of HIV/TB Co-Infected Persons
Authors: Rajasingham Radha , Pollock Nira R , Linas Benjamin P 
Published: September 2017

AbstractBackgroundPersons with HIV and tuberculosis (TB) co-infection require transaminase monitoring while on hepatotoxic medications. A novel paper-based, point-of-care transaminase test is in development at an anticipated cost of $1 per test.MethodsTo project long-term clinical outcomes and estimate the cost-effectiveness of using a paper-based fingerstick test to monitor for drug-induced liver injury (DILI), as compared with automated testing and with no laboratory monitoring. The design was a decision analytic model, including deterministic and probabilistic sensitivity analyses. Data sources were observational cohorts and a validation study of the paper-based test. The target population was HIV/TB co-infected persons in South Africa on antiretroviral therapy who were initiating TB therapy. Interventions: (1) clinical (no laboratory) monitoring; (2) monitoring using the paper-based test with a ≥120 IU/mL threshold for positivity; (3) monitoring using the paper-based test with a ≥200 IU/mL threshold for positivity; (4) monitoring using the paper-based test using 1 of 3 categories: &lt;120 IU/mL, 120 to 200 IU/mL, and &gt;200 IU/mL (“bin placement”); (5) monitoring using automated ALT testing using the same 3 categories (“automated testing”). The outcome measures were discounted quality-adjusted life-years (QALYs), costs, and incremental cost-effectiveness ratios (ICERs).ResultsThe ICER of automated testing was $5180/QALY. Use of the paper-based test with the bin placement strategy was cost-effective compared with clinical monitoring alone.ConclusionAt its current performance, monthly DILI monitoring by bin placement using the paper-based test was cost-effective, compared with clinical monitoring, in HIV/TB co-infected persons in South Africa.
Transitional Objects to Faciliate Grieving Following Perinatal Loss
Authors: LeDuff Lawrence D. , Bradshaw Wanda T. , Blake Stephanie M. 
Published: September 2017

Background:
Parents who experience a perinatal loss often leave the hospital with empty arms and no tangible mementos to validate the parenting experience. Opportunities to create parenting experiences with transitional objects exist following the infant's death.

Purpose:
This article offers suggestions for staff in units where infant loss is possible to best assist parents in optimal grieving through the offering of transitional bereavement objects.

Methods/Search Strategy:
CINAHL Complete, MEDLINE, and the Cochrane Database of Systematic Reviews were searched using the following key words—perinatal bereavement, grief, perinatal loss, transitional objects, bereavement photography—and the search was limited to 5 years and the English language.

Findings/Results:
Recommendations exist and are well supported by leading neonatal and perinatal nursing and medicine organizations for the use of transitional objects to facilitate healthy grieving when parents experience perinatal loss. Transitional objects are mementos that validate the meaning of parenthood—even if the physical act of parenting was brief. Nursing and medical staff have significant roles in guiding parents to a healthy state of bereavement and ultimately managing long-term grief.

Implications for Practice:
Transitional objects can be provided by staff that are low-cost or free, such as taking photographs for parents, or they can involve purchased products from perinatal bereavement programs. In the latter case, funding needs are a consideration for budgeting decisions.

Implications for Research:
Immediately following a loss, parents experience a brief sense of healing after receiving mementos of their infant. However, further research is needed to assess long-term effects of receiving transitional objects following perinatal loss.
Overcoming Education Failures and Retakes
Authors: Wynn Stephanie T. 
Published: September 2017

ABSTRACT:
The retention of students is a major challenge for nursing education programs. Although students who fail can often retake courses, negative internalities may occur. After a failure, students regularly present with emotional distress. A mental health practitioner, who is a nursing faculty member, is ideal to assist these students and offer support. The integration of spirituality as a coping mechanism for these students can serve as a protective factor.
Welcome Day
Authors: Wyss Lora , Hess Rosanna F. 
Published: September 2017

ABSTRACT:

Welcome Day, one specific day in the life of Hartville Migrant Ministry (HMM), a faith-based ministry in Ohio, illustrates the organization's vision, mission, and community collaboration. Migrant and seasonal farm workers, the Migrant Head Start program, HMM and Welcome Day, interprofessional collaboration, and Malone University School of Nursing faculty and students support are discussed. Programs and activities presented here could be reproduced in other communities.
African American Hemodialysis Patients' Perceptions of Faith and Nursing
Authors: Nix Elizabeth Seaton 
Published: September 2017

ABSTRACT:
Numerous quantitative studies have been conducted with African Americans (AAs) receiving hemodialysis. This article shares a portion of a larger qualitative study that explored the role spirituality plays in the lives of AAs undergoing hemodialysis for management of end-stage renal disease (ESRD). Interview questions centered on the roles of spirituality, health beliefs, and different social support systems used in coping. By understanding the perceptions of AAs with ESRD, nurses and other providers can offer better support.
Racial and Socioeconomic Differences Manifest in Process Measure Adherence for Enhanced Recovery After Surgery Pathway
Authors: Leeds Ira L. , Alimi Yewande , Hobson Deborah R. , Efron Jonathan E. , Wick Elizabeth C. , Haut Elliott R. , Johnston Fabian M. 
Published: September 2017

BACKGROUND:
Adherence to care processes and surgical outcomes varies by population subgroups for the same procedure. Enhanced recovery after surgery pathways are intended to standardize care, but their effect on process adherence and outcomes for population subgroups is unknown.

OBJECTIVE:
This study aims to demonstrate the association between recovery pathway implementation, process measures, and short-term surgical outcomes by population subgroup.

DESIGN:
This study is a pre- and post-quality improvement implementation cohort study.

SETTING:
This study was conducted at a tertiary academic medical center.

INTERVENTION:
A modified colorectal enhanced recovery after surgery pathway was implemented.

PATIENTS:
Patients were included who had elective colon and rectal resections before (2013) and following (2014–2016) recovery pathway implementation.

MAIN OUTCOME MEASURE:
Thirty-day outcomes by race and socioeconomic status were analyzed using a difference-in-difference approach with correlation to process adherence.

RESULTS:
We identified 639 cases (199 preimplementation, 440 postimplementation). In these cases, 75.2% of the patients were white, and 91.7% had a high socioeconomic status. Groups were similar in terms of other preoperative characteristics. Following pathway implementation, median lengths of stay improved in all subgroups (–1.0 days overall, p ≤ 0.001), but with no statistical difference by race or socioeconomic status (p = 0.89 and p = 0.29). Complication rates in both racial and socioeconomic groups were no different (26.4% vs 28.8%, p = 0.73; 27.3% vs 25.0%, p = 0.86) and remained unchanged with implementation (p = 0.93, p = 0.84). By race, overall adherence was 31.7% in white patients and 26.5% in nonwhite patients (p = 0.32). Although stratification by socioeconomic status demonstrated decreased overall adherence in the low-status group (31.8% vs 17.1%, p = 0.05), white patients were more likely to have regional pain therapy (57.1% vs 44.1%, p = 0.02) with a similar trend seen with socioeconomic status.

LIMITATIONS:
Data were collected primarily for quality improvement purposes.

CONCLUSIONS:
Differences in outcomes by race and socioeconomic status did not arise following implementation of an enhanced recovery pathway. Differences in process measures by population subgroups highlight differences in care that require further investigation. See Video Abstract at http://links.lww.com/DCR/A386.