bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between skeletal muscle mass and cardiac function during exercise in community‐dwelling older adults
Authors: Sugie Masamitsu , Harada Kazumasa , Takahashi Tetsuya , Nara Marina , Ishikawa Joji , Koyama Teruyuki , Kim Hunkyung , Tanaka Jun , Fujimoto Hajime , Obuchi Shuichi , von Haehling Stephan , Kyo Syunei , Ito Hideki 
Published: April 2017

AbstractAimsThis study aimed to investigate the relationship between skeletal muscle mass and cardiac functional parameters in older adults during cardiopulmonary exercise testing (CPET).Methods and resultsSixty‐three Japanese community‐dwelling older adults were enrolled (20 men and 43 women; mean age 80 years, range 65–97 years). Cardiac functional parameters during exercise were assessed using CPET. Skeletal muscle mass index (SMI) was calculated by dividing the appendicular lean mass (measured using dual‐energy X‐ray absorptiometry) by height in metres squared. Subjects were divided into two groups: men with SMI ≥ 7.0 kg/m2 and women with SMI ≥ 5.4 kg/m2 (non‐sarcopenic group); or men with SMI < 7.0 kg/m2 and women with SMI < 5.4 kg/m2 (sarcopenic group). There were significant positive correlations between SMI and peak oxygen uptake (VO2) (r = 0.631, P < 0.001), and between SMI and peak VO2/heart rate (HR) (r = 0.683, P < 0.001). However, only peak VO2/HR significantly differed between groups in both sexes. Multiple linear regression analyses with peak VO2/HR as a dependent variable showed that SMI was the only independent determinant after adjusting for potential confounders. After 4 month follow‐up of 47 participants, there was still a significant positive correlation between SMI and peak VO2/HR (r = 0.567, P < 0.001), and between percent change of SMI and percent change of peak VO2/HR (r = 0.305, P < 0.05).ConclusionsPeak VO2/HR, an index of stroke volume at peak exercise, was associated with SMI. This indicates that skeletal muscle mass might affect cardiac function during exercise.
Antibacterial electrospun chitosan‐based nanofibers: A bacterial membrane perforator
Authors: Arkoun Mounia , Daigle France , Heuzey Marie‐Claude , Ajji Abdellah 
Published: April 2017

AbstractThis study investigates the antibacterial action of chitosan‐based nanofibers (CNFs) obtained by the electrospinning process on the permeability of bacterial membranes. The bactericidal efficiency of CNFs was first determined against Gram‐negative Escherichia coli and Salmonella Typhimurium, and Gram‐positive Staphylococcus aureus and Listeria innocua bacteria as a baseline. The results strongly suggest that CNFs interact with the negatively charged bacterial cell wall causing membrane rupture and inducing leakage of intracellular components among which are proteins and DNA. Results clearly indicate that the release of such components after contact with CNFs is an indication of membrane permeabilization and perforation, as pore formation was observed in transmission electron microscopy (TEM). This work suggests a plausible antibacterial mechanism of action of CNFs and also provides clear evidence in favor of chitosan as a bacterial membrane disruptor and perforator. As a result, CNFs can find promising applications as bioactive food packaging materials capable to extend shelf life of food products while inhibiting the spread of alteration flora and foodborne pathogens.
What Do I Say Next? Using the Third Turn to Build Productive Instructional Discussions
Authors: Ford‐Connors Evelyn , Robertson Dana A. 
Published: April 2017

AbstractResearch has strongly supported the role of classroom talk as a valuable teaching and learning tool. Carefully crafted teacher–student discussions that encourage broad student participation and knowledge building correlate with increased knowledge generation and higher academic achievement. To better understand classroom talk as an instructional lever, researchers have identified a number of teacher talk moves associated with increased student participation, critical reasoning, and improved comprehension of texts and content. In particular, when teachers make use of the third turn in their talk with students, they create opportunities for more productive student interactions with content and one another. This article examines how teachers use the third turn to orchestrate productive discussions, using examples based on content analysis of teacher–student discussions in classroom settings.
Determination of irinotecan, SN‐38 and SN‐38 glucuronide using HPLC/MS/MS: Application in a clinical pharmacokinetic and personalized medicine in colorectal cancer patients
Authors: Atasilp Chalirmporn , Chansriwong Pichai , Sirachainan Ekapob , Reungwetwattana Thanyanan , Puangpetch Apichaya , Prommas Santirhat , Sirilerttrakul Suwannee , Rerkarmnuaychoke Budsaba , Wongwaisayawan Sansanee , Sukasem Chonlaphat 
Published: April 2017

BackgroundIrinotecan (CPT‐11) is chemotherapy used mainly in the metastatic colorectal cancer. The purpose of this study was to develop and validate the LC‐MS/MS for the simultaneous determination of CPT‐11, SN‐38, and SN‐38G.MethodsA 100 μL of plasma was prepared after protein precipitation and analyzed on a C18 column using 0.1% acetic acid in water and 0.1% acetic acid in acetonitrile as mobile phases. The mass spectrometer worked with multiple reaction monitoring (MRM) in positive scan mode. The standard curves were linear on a concentration range of 5‐10 000 ng/mL for CPT‐11, 5‐1000 ng/mL for SN‐38, and 8‐1000 ng/mL for SN‐38G.ResultsIn this assay, the intra and interday precision consisted of ≤9.11% and ≤11.29% for CPT‐11, ≤8.70% and 8.31% for SN‐38, and ≤9.90 and 9.64% for SN‐38G.ConclusionThis method was successfully used to quantify CPT‐11, SN‐38, and SN‐38G and applied to a pharmacokinetic study.
Crossing Borders: Multicultural Counseling With Puerto Rican Migrant Women
Authors: Comas‐Diaz Lillian 
Published: April 2017

Puerto Rican migrant women require cultural‐specific counseling. The intersection of ethnicity, gender, culture, and sociopolitical contexts affects Puerto Rican migrant women's psychological coping and identity development. A psychology of place lens is used to discuss how numerous Puerto Rican migrant women nurture their identity development from borderlands (transfronterizas) totransboricuas(trans–Puerto Rican). A case vignette illustrates the use of a multicultural counseling approach to address Puerto Rican migrant women's psychological needs.Las mujeres puertorriqueñas emigrantes requieren servicios de consejería culturalmente específicos. La intersección de etnicidad, sexo, cultura y contextos sociopolíticos afecta a la capacidad de afrontamiento y el desarrollo de la identidad de las mujeres puertorriqueñas emigrantes. Se usa el enfoque de la psicología de lugar para discutir cómo muchas mujeres puertorriqueñas emigrantes cultivan el desarrollo de su identidad de transfronterizas a transboricuas. Se usa la viñeta de un caso para ilustrar el uso de una aproximación multicultural a la consejería para tratar las necesidades psicológicas de las mujeres puertorriqueñas emigrantes.
Perceived Multicultural Counseling Competence of Malaysian Counselors: An Exploratory Study
Authors: Aga Mohd Jaladin Rafidah 
Published: April 2017

This study investigated the nature and extent of perceived multicultural counseling competence (MCC) of 508 professional counselors in Malaysia using a national survey approach. Differences in counselors' perceived MCC pertaining to gender, ethnicity, highest education, and multicultural training were examined. Results revealed 5 factors as constituents of MCC and significant differences in perceived MCCs due to ethnicity, highest education, and participation in multicultural training. Implications for future research, counselor education, and counseling practice are discussed.Este estudio investigó la naturaleza y la extensión de la competencia en consejería multicultural (MCC, por sus siglas en inglés) percibida de 508 consejeros profesionales en Malasia usando un enfoque de encuesta nacional. Se examinaron las diferencias en la MCC percibida de los consejeros respecto a sexo, etnicidad, nivel máximo de educación y capacitación multicultural. Los resultados revelaron 5 factores constituyentes de MCC y diferencias significativas en las MCC debido a etnicidad, nivel máximo de educación y participación en capacitación multicultural. Se discuten las implicaciones para investigaciones futuras, educación de consejeros y práctica de la consejería.
Development of a 3D HUD using a tunable bandpass filter for wavelength multiplexing
Authors: Coni Philippe , Bardon Jean‐Luc , Gueguen Aude , Grossetête Matthieu 
Published: April 2017

AbstractA 3D stereoscopic head‐up display using a tunable bandpass filter to perform left and right image spectral separation is presented. Using a single filter reduces the size and the cost of the head‐up display optical engine and enables each spectral band to be accurately tuned. Experiments performed on the first prototype demonstrate the ability to continuously tune the bandpass frequency on 30‐nm range while keeping a 20‐nm bandwidth. Such a system avoids the use of a bulky and costly rotating wheel and enables the use of holographic optical elements known to be wavelength selective.
Quantum dot light emitting devices for photomedical applications
Authors: Chen Hao , He Juan , Lanzafame Raymond , Stadler Istvan , Hamidi Hamid El , Liu Hui , Celli Jonathan , Hamblin Michael R. , Huang Yingying , Oakley Emily , Shafirstein Gal , Chung Ho‐Kyoon , Wu Shin‐Tson , Dong Yajie 
Published: April 2017

AbstractWhile OLEDs have struggled to find a niche lighting application that can fully take advantage of their unique form factors as thin, flexible, lightweight and uniformly large‐area luminaire, photomedical researchers have been in search of low‐cost, effective illumination devices with such form factors that could facilitate widespread clinical applications of photodynamic therapy (PDT) or photobiomodulation (PBM). Although existing OLEDs with either fluorescent or phosphorescent emitters cannot achieve the required high power density at the right wavelength windows for photomedicine, the recently developed ultrabright and efficient deep red quantum dot light emitting devices (QLEDs) can nicely fit into this niche. Here, we report for the first time the in‐vitro study to demonstrate that this QLED‐based photomedical approach could increase cell metabolism over control systems for PBM and kill cancerous cells efficiently for PDT. The perspective of developing wavelength‐specific, flexible QLEDs for two critical photomedical fields (wound repair and cancer treatment) will be presented with their potential impacts summarized. The work promises to generate flexible QLED‐based light sources that could enable the widespread use and clinical acceptance of photomedical strategies including PDT and PBM.
Removal of an exotic fish influences amphibian breeding site selection
Authors: Pollard Carla J. , Stockwell Michelle P. , Bower Deborah S. , Garnham James I. , Pickett Evan J. , Darcovich Kerry , O'meara Jenny , Clulow John , Mahony Michael J. 
Published: April 2017

ABSTRACTFor pond‐breeding species, the distribution of larvae is a reflection of habitat suitability and adult breeding site selection. Some species preferentially breed in ephemeral ponds, which can provide benefits for larvae. An alternative strategy used by adults to increase offspring survival is to detect aquatic predators and avoid them when selecting breeding sites. We investigated whether either of these types of breeding site selection are contributing to the negative correlation between the distributions of tadpoles of the threatened green and golden bell frog (Litoria aurea) and the introduced eastern gambusia (Gambusia holbrooki) in Sydney, Australia. From 2003 to 2012 we drained ponds to temporarily remove gambusia and examined the effect of removal on the numbers of male, female, and juvenile frogs, and tadpoles. We found that males preferentially selected fish‐free ponds as breeding sites. In addition, the removal of gambusia increased tadpole abundance to over 140 times that of an undrained pond. Pond draining did not influence female or juvenile abundances. The ability to detect and avoid gambusia may be mitigating the effect of predation to a certain extent. We conclude that pond draining to remove exotic fish is an effective strategy that can be used to greatly increase the reproductive success of this and potentially other threatened amphibian species in the presence of exotic predators. © 2017 The Wildlife Society.
The effect of n‐acetyl‐cysteine on recovery of the facial nerve after crush injury
Authors: Rivera Andrew , Raymond Mallory , Grobman Ariel , Abouyared Marianne , Angeli Simon I. 
Published: April 2017

ObjectiveFacial nerve dysfunction can vary in severity and recovery is dependent on the character of the injury. N‐acetyl‐cysteine prevents oxidative stress and cellular damage, and its use in the setting of nerve dysfunction from crush injury has not yet been established. In this study, rats with facial nerve crush injury will be treated with n‐acetyl‐cysteine or control and functional recovery and electrophysiologic outcome will be compared.Study DesignProspective, randomized animal studyMethodsTwenty‐four Wistar rats underwent unilateral facial nerve crush injury. Rats were implanted with a subcutaneous osmotic pump filled with saline (n = 12) or n‐acetyl‐cysteine 50 mg/kg/day (n = 12). Functional and electromyographic recovery was recorded at two and four weeks postoperatively.ResultsWhen compared to untreated rats, n‐acetyl‐cysteine treated rats had a greater electromyography amplitude recovery at 2 weeks with regard to eye blink (p=0.006) but not vibrissae function. At four weeks, the electromyography amplitude recovery of the vibrissae function was greater in n‐acetyl‐cysteine treated rats (P=0.001), but the amplitude recovery difference in eye blink was only marginally significant between groups (p=0.07). The functional score was higher in n‐acetyl‐cysteine‐treated rats than in untreated rats at all of the time points.ConclusionThis study demonstrated that n‐acetyl‐cysteine facilitated facial nerve recovery with improved functional and electromyography outcomes in the setting of crush injury.Level of EvidenceNA
Enhanced Self‐Renewal and Accelerated Differentiation of Human Fetal Neural Stem Cells Using Graphene Oxide Nanoparticles
Authors: Kim Jin , Yang Kisuk , Lee Jong Seung , Hwang Yong Hwa , Park Hyun‐Ji , Park Kook In , Lee Dong Yun , Cho Seung‐Woo 
Published: April 2017

Graphene oxide (GO) has received increasing attention in bioengineering fields due to its unique biophysical and electrical properties, along with excellent biocompatibility. The application of GO nanoparticles (GO‐NPs) to engineer self‐renewal and differentiation of human fetal neural stem cells (hfNSCs) is reported. GO‐NPs added to hfNSC culture during neurosphere formation substantially promote cell‐to‐cell and cell‐to‐matrix interactions in neurospheres. Accordingly, GO‐NP‐treated hfNSCs show enhanced self‐renewal ability and accelerated differentiation compared to untreated cells, indicating the utility of GO in developing stem cell therapies for neurogenesis.
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Changes in the cell population in brain white matter in multiple system atrophy
Authors: Nykjær Charlotte Havelund , Brudek Tomasz , Salvesen Lisette , Pakkenberg Bente 
Published: April 2017

ABSTRACTBackground: Multiple system atrophy (MSA) is a sporadic progressive neurodegenerative disorder with adult onset and unknown etiology. Clinically it is characterized by autonomic failure, cerebellar ataxia, parkinsonism, and corticospinal dysfunction in any combination and with varying severity.Objectives and Methods: To establish the extent of involvement of the white matter in the disease, we have used stereology to quantify the total number of neurons and glial cells (oligodendrocytes, astrocytes, and microglia) in the brains from 10 MSA patients and 11 controls.Results: The mean total number of white matter interstitial neurons in the patient brains was 0.5 × 109 (coefficient of variation = standard deviation/mean = 0.37), which was significantly lower than the 1.1 × 109 (0.41) in the control brains (P = .001) and equal to a reduction by ∼50%. The patient brains had a significantly higher number of white matter microglia, 1.5 × 109 (0.47) versus 0.7 × 109 (0.39) microglia in the control subjects (P = .003) and equal to an increase by ∼ 100%. There was no significant difference in mean total numbers of white matter oligodendrocytes and astrocytes between the groups.Conclusions: We found widespread microgliosis without concomitant astrogliosis in brain white matter in MSA patients and demonstrated an absence of significant oligodendrocyte degeneration. The exact role of oligodendrocytes in MSA pathogenesis, including neurodegeneration, remains to be elucidated. © 2017 International Parkinson and Movement Disorder Society
Recovery‐stress patterns and low back pain: Differences in pain intensity and disability
Authors: Heidari Jahan , Mierswa Tobias , Hasenbring Monika , Kleinert Jens , Levenig Claudia , Belz Johanna , Kellmann Michael 
Published: April 2017

AbstractBackgroundRecovery describes a restoring process influencing the health conditions of individuals but a potential link to low back pain (LBP) has not been scrutinized so far. Psychological strategies to deal with LBP have been considered within the biopsychosocial approach but substantial evidence regarding specific psychological underpinnings remains elusive. The current study aimed to compare individuals with different recovery–stress patterns (i.e. specific combinations of recovery/stress) regarding their pain and disability in the lower back.MethodsCross‐sectional data from 265 physically active individuals with non‐specific LBP were collected via standardized questionnaires. The participants engaged in prescribed exercise therapy provided by a healthcare professional owing to their back burden. A k‐means cluster analysis identified three clusters.ResultsCluster 1 entailed individuals with high recovery and low stress values, Cluster 2 represented participants with medium scores on both dimensions and Cluster 3 included participants with low recovery and high stress values. The statistical analyses for pain intensity using analyses of covariance indicated significantly higher values for Cluster 3 compared with Clusters 1 and 2 for worst pain intensity (p < 0.001 and p = 0.003, respectively) and mean pain intensity (p < 0.001 and p = 0.001, respectively). The disability comparisons using non‐parametric tests showed significantly higher LBP‐related disability in Cluster 3 than Cluster 1 on two disability measures.ConclusionsThe findings indicate an association between detrimental recovery–stress patterns and LBP. Examining the role of recovery has innovative practical relevance for LBP prevention and rehabilitation through the implementation of approaches to enhance recovery in relevant programmes.
Enhancing the power output of PV modules by considering the view factor to sky effect and rearranging the interconnections of solar cells
Authors: Peled Assaf , Appelbaum Joseph 
Published: April 2017

AbstractThe solar diffuse radiation incident on a photovoltaic (PV) module is unevenly distributed along the module's width because its solar‐cells “see” different view‐factor values with respect to their position. This fact causes PV modules to experience undesired power losses brought about by current mismatch. The paper addresses this issue and presents new interconnection strategies for the module's cells. The proposed interconnections are shown to introduce power gain vis‐à‐vis the all‐series connected module. Having established the theoretical framework, a case study is examined, comparing two sites with considerable different amounts of diffuse radiation with the aim of quantifying the power production enhancement with regard to the site's prevailing annual extent of diffuse radiation. It is found, for example, that by converting the all‐series cell interconnection into parallel strips in Desert Rock (NV, USA), each module can be supplemented with a 6.5 [kWph] annually on average. The study may have financial implications for the PV industry which strives to increase power generation while maintaining reduced costs. Copyright © 2017 John Wiley & Sons, Ltd.
How does the core sit inside the mantle?
Authors: Coja‐Oghlan Amin , Cooley Oliver , Kang Mihyun , Skubch Kathrin 
Published: April 2017

AbstractThe k‐core, defined as the maximal subgraph of minimum degree at least k, of the random graph has been studied extensively. In a landmark paper Pittel, Wormald and Spencer [J Combin Theory Ser B 67 (1996), 111–151] determined the threshold dk for the appearance of an extensive k‐core.The aim of the present paper is to describe how the k‐core is “embedded” into the random graph in the following sense. Let and fix . Colour each vertex that belongs to the k‐core of in black and all remaining vertices in white. Here we derive a multi‐type branching process that describes the local structure of this coloured random object as n tends to infinity. This generalises prior results on, e.g., the internal structure of the k‐core.In the physics literature it was suggested to characterize the core by means of a message passing algorithm called Warning Propagation. Ibrahimi, Kanoria, Kraning and Montanari [Ann Appl Probab 25 (2015), 2743–2808] used this characterization to describe the 2‐core of random hypergraphs. To derive our main result we use a similar approach. A key observation is that a bounded number of iterations of this algorithm is enough to give a good approximation of the k‐core. Based on this the study of the k‐core reduces to the analysis of Warning Propagation on a suitable Galton‐Watson tree. © 2017 Wiley Periodicals, Inc. Random Struct. Alg., 51, 459–482, 2017
Extending Category Partition's Base Choice criterion to better support constraints
Authors: Khalsa Sunint Kaur , Labiche Yvan 
Published: April 2017

AbstractTo ensure software is performing as intended, it can be black‐box or white‐box tested. Category partition is a black‐box, specification‐based testing technique that begins by identifying the parameters, categories (characteristics of parameters), and choices (acceptable values for categories). These choices are then combined to form test frames on the basis of various criteria such as Base Choice and Each Choice. To ensure that the combinations of choices are feasible, constraints on choices are introduced. Combining choices, while accounting for constraints, to form an each choice adequate test set is feasible (eg, using constrained covering arrays from combinatorial testing). However, the Base Choice criterion has not been defined to specifically account for constraints on choices, resulting in adverse consequences. In this paper, we introduce two extensions to the Base Choice criterion, namely, Constrained Base Choice and Extended Constrained Base Choice to specifically account for (complex) constraints on choices. We use a number of academic and industrial case studies to compare different adequacy criteria, including the new ones, in terms of cost and effectiveness at finding faults. Results show the performance of the new criteria equivalent to a 3‐way combination criterion with a much smaller cost.
Cross-Cultural Child Development for Social Workers
Authors: Robinson Lena 
Published: April 2017

Social workers today operate in an increasingly ethnically diverse society, yet many of the models that they use fail to reflect that diversity.
Lena Robinson's exciting and innovative text draws on literature from Britain and North America to explain child development from a cross-cultural, black and ecological perspective. Using practice examples to illuminate key points for social workers, she considers a range of key topics from attachment to identity and communication to socialization. This will be essential reading for social workers at all stages of their careers who want to develop strength-based, anti-racist and culturally sensitive practice.