bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the Edges Version of Atom-Bond Connectivity Index of Nanotubes
Authors: Gao Wei , Husin Mohamad Nazri , Farahani Mohammad Reza , Imran Muhammad 
Published: May 2017

The edge version atom-bond connectivity (ABCe) indices of graph G is defined as ABCe(G) = <inline-formula> <mml:math display="block"> <mml:msub> <mml:mo>∑</mml:mo> <mml:mrow> <mml:mi>e</mml:mi><mml:mi>f</mml:mi><mml:mo>∈</mml:mo><mml:mi>E</mml:mi><mml:mo
stretchy="false">(</mml:mo><mml:mi>L</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>G</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mo stretchy="false">)</mml:mo> </mml:mrow> </mml:msub> <mml:msqrt>
<mml:mrow> <mml:mo stretchy="false">(</mml:mo><mml:msub> <mml:mi>d</mml:mi> <mml:mrow> <mml:mi>L</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>G</mml:mi><mml:mo stretchy="false">)</mml:mo> </mml:mrow>
</mml:msub> <mml:mo stretchy="false">(</mml:mo><mml:mi>e</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mo>+</mml:mo><mml:msub> <mml:mi>d</mml:mi> <mml:mrow> <mml:mi>L</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>G</mml:mi><mml:mo
stretchy="false">)</mml:mo> </mml:mrow> </mml:msub> <mml:mo stretchy="false">(</mml:mo><mml:mi>f</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mo>−</mml:mo><mml:mn>2</mml:mn><mml:mo stretchy="false">)</mml:mo><mml:mo>/</mml:mo><mml:mo
stretchy="false">(</mml:mo><mml:msub> <mml:mi>d</mml:mi> <mml:mrow> <mml:mi>L</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>G</mml:mi><mml:mo stretchy="false">)</mml:mo> </mml:mrow> </mml:msub>
<mml:mtext> (</mml:mtext><mml:mi>e</mml:mi><mml:mtext>)</mml:mtext><mml:mo>×</mml:mo><mml:msub> <mml:mi>d</mml:mi> <mml:mrow> <mml:mi>L</mml:mi><mml:mo stretchy="false">(</mml:mo><mml:mi>G</mml:mi><mml:mo
stretchy="false">)</mml:mo> </mml:mrow> </mml:msub> <mml:mo stretchy="false">(</mml:mo><mml:mi>f</mml:mi><mml:mo stretchy="false">)</mml:mo><mml:mo stretchy="false">)</mml:mo><mml:mo>,</mml:mo> </mml:mrow>
</mml:msqrt> </mml:math></inline-formula> where dL(G)(e) denotes the degrees of an edge of line graph of G. The goal of this paper is to investigate ABCe index for some nanotubes.
Proteinase 3: the odd one out that became an autoantigen
Authors: Martin Katherine R , Witko-Sarsat Véronique 
Published: May 2017

AbstractNeutrophils are critical in the defense against bacterial and fungal pathogens, and they also modulate the inflammatory process. The areas where neutrophils are studied have expanded from the restricted field of antibacterial defense to the modulation of inflammation and finally, to fine-tuning immune responses. As a result, recent studies have shown that neutrophils are implicated in several systemic autoimmune diseases, although exactly how neutrophils contribute to these diseases and the molecular mechanisms responsible are still under investigation. In a group of autoimmune vasculitides associated with anti-neutrophil cytoplasmic antibodies (AAVs), granulomatosis with polyangiitis (GPA) illustrates the concept that autoimmunity can develop against one specific neutrophil protein, namely, proteinase 3 (PR3), one of the four serine protease homologs contained within azurophilic granules. In this review, we will focus on recent molecular analyses combined with functional studies that provide clear evidence that the pathogenic properties of PR3 are not only a result of its enzymatic activity but also mediated by a particular structural element—the hydrophobic patch—which facilitates associations with various proteins and lipids and permits anchorage into the plasma membrane. Furthermore, these unique structural and functional characteristics of PR3 might be key contributors to the systemic inflammation and to the immune dysregulation observed in GPA.
Gods, Ghosts, and Ancestors as Reflected in Death Rituals in a Chinese Village
Authors: Chen Gang 
Published: May 2017

AbstractDeath rituals have played an important role in Chinese society for thousands of years. This article, based on ethnographic data collected in a village in Chongqing in southwestern China, reconstructs the sequence of preburial, funeral, and postburial rituals performed by the villagers. Then it discusses the belief system associated with these rituals, which includes traditional Chinese cosmology, the nature of ancestors, and the roles of feng shui. It concludes that the death ritual in this village helps people adjust to life in fast-changing, modern rural China.
A case of previously undiagnosed acute intermittent porphyria in a 34-year-old primigravida with gestational diabetes mellitus
Authors: Žebeljan Ivan , Anzeljc Veronika , Serdinšek Tamara , Mujezinović Faris 
Published: May 2017

Abstract
Porphyrias are very rare and easily overlooked diseases in pregnancy. Among these eight known metabolic disorders, acute intermittent porphyria (AIP) is the most common and most severe type. An enzymatic alteration in the haem biosynthesis pathway causes liver overproduction of neurotoxic toxic metabolites, which cause attacks of acute neurovisceral symptoms, severe abdominal pain and/or skin lesions. Women with AIP can sometimes develop their first acute attack during pregnancy, and because the symptoms are unspecific, the diagnosis is difficult to obtain and often missed. However, prompt diagnosis of AIP during pregnancy is crucial as treatment can significantly improve the pregnancy outcome. The backbone of the therapy is food rich with carbohydrates, complemented by 20% glucose infusion and adequate pain control. We present a case of previously undiagnosed AIP in a 34-year primigravida, whose treatment was especially challenging due to co-existing gestational diabetes mellitus and problems with the central venous catheter.
Does verruca vulgaris affect social anxiety and self-esteem in adolescents?
Authors: Unal Dilek , Cengiz Fatma Pelin , Emiroglu Nazan 
Published: May 2017

Abstract

Objective
Sensitivity about appearance is one of the sine qua non of adolescence and adolescents’ self-esteem effecting their socialization processes. We explored if verruca vulgaris, a common visible infectious skin disease, affects social anxiety levels and self-esteem in adolescents compared to controls. Also, the difference in sociodemographic properties between two groups and the effect of clinical properties (the distribution and number of warts) on these parameters were investigated in the patient group.

Materials and methods
The study group consisted 98 adolescents (49 controls and 49 patients) without other medical/psychiatric diseases. The Sociodemographic form (SDF), the Çapa Social Phobia Scale for Children and Adolescents (ÇCASPS) and the Rosenberg Self-Esteem Scale (RSES) were completed by both groups.

Results
There was no difference in social anxiety levels and self-esteem between the two groups. Also, the control and patient groups were found matched. However, lower self-esteem was the only factor that increased the risk for social phobia in the patient group.

Conclusion
Verruca vulgaris distributed in hands and face in adolescents were not found to be related with higher social anxiety and lower self-esteem. However, clinicians should monitor psychiatric symptoms and especially lower self-esteem should be taken into account.
Drosophila simulans: A Species with Improved Resolution in Evolve and Resequence Studies
Authors: Barghi Neda , Tobler Raymond , Nolte Viola , Schlötterer Christian 
Published: May 2017

AbstractThe combination of experimental evolution with high-throughput sequencing of pooled individuals—i.e., evolve and resequence (E&R)—is a powerful approach to study adaptation from standing genetic variation under controlled, replicated conditions. Nevertheless, E&R studies in Drosophila melanogaster have frequently resulted in inordinate numbers of candidate SNPs, particularly for complex traits. Here, we contrast the genomic signature of adaptation following ∼60 generations in a novel hot environment for D. melanogaster and D. simulans. For D. simulans, the regions carrying putatively selected loci were far more distinct, and thus harbored fewer false positives, than those in D. melanogaster. We propose that species without segregating inversions and higher recombination rates, such as D. simulans, are better suited for E&R studies that aim to characterize the genetic variants underlying the adaptive response.
Cuttings-Transport Simulation Combined With Large-Scale-Flow-Loop Experimental Results and Logging-While-Drilling Data for Hole-Cleaning Evaluation in Directional Drilling
Authors: Naganawa Shigemi , Sato Ryosuke , Ishikawa Masaki 
Published: May 2017

SummaryThe authors have developed a 1D two-layer-model transient-cuttings-transport simulator that predicts the transient behaviors of cuttings transport, including the concentration and slip velocity of suspended cuttings, bed height of cuttings, annular pressure, and equivalent circulating density (ECD) along the entire trajectory of a complex extended-reach well. Model parameters, such as annulus-friction factor, cuttings-deposition rate, and re-entrainment rate, were determined from numerous experiments previously performed by use of a large-scale cuttings-transport flow-loop apparatus. This apparatus simulates the complex flows in borehole annuli at various inclination angles, ranging from vertical to horizontal. In this study, the authors validate the model and analyze the cuttings transport by use of field data in a directional well, in which the annular ECD was measured by logging while drilling (LWD), and the rate of the returned cuttings was measured at the surface. On the basis of the simulation study, the potential of the developed transient-cuttings-transport simulator for the predrilling- and post-drilling-phase analyses is discussed. Moreover, the authors evaluate the transient-hole-cleaning conditions and the ECD behavior from the LWD data.
Design and Performance of Annular-Pressure-Buildup Mitigation Techniques
Authors: Sathuvalli Udaya B. , Pilko R. M. , Gonzalez R. A. , Pai R. M. , Sachdeva P.. , Suryanarayana P. V. 
Published: May 2017

Summary
Subsea wells use annular-pressure-buildup (APB) mitigation devices to ensure well integrity. We define mitigation techniques that control APB by reducing lateral heat loss from the production tubing to the wellbore as Type I techniques. Mitigation techniques that control the stiffness (psi/°F) of an annulus by modifying its contents and boundaries are defined as Type II techniques.
Although the physics of APB mitigation is well-understood, the reliability of a mitigation strategy or its interaction with other parts of the wellbore is not always quantifiable. This is partly because of the lack of a unified approach to analyze mitigation strategies, and partly because of the lack of downhole data after well completion. Simply stated, the engineer is hard-pressed to find computational-predictive methods to assess alternative scenarios and strategies within the framework of the design basis during the life of the well. In this light, our paper presents a quantitative approach to design the currently used APB mitigation strategies: rupture disks, syntactic foams, nitrified spacers, and vacuum-insulated tubing (VIT). In each case, the design is linked to the notion of “allowable APB” in an annulus, which in turn is tied to the design of the casing strings, and thus to wellbore integrity. We also review APB mitigation techniques that have been used less frequently or are awaiting proof of concept/field trial.
Stuck-Pipe Prediction by Use of Automated Real-Time Modeling and Data Analysis
Authors: Salminen Kent , Cheatham Curtis , Smith Mark , Valiullin Khaydar 
Published: May 2017

Summary
A real-time method is presented to predict impending stuck pipe with sufficient warning to prevent it. The new method uses automated analysis of real-time modeling coupled with real-time data analysis. It can be applied to all well types for any well operation, including drilling, casing running, completion activities, and re-entries. The method uses leading indicators of stuck pipe that were identified by use of historical data sets of 36 stuck-pipe incidents in the Eagle Ford, Utica, and Permian and in the Gulf of Mexico. Two case histories show the utility of the new method in shale and carbonate horizontal wells for both drilling and off-bottom operations.
The new method combines two types of analysis: use of hydraulics and torque-and-drag (T&D) software to determine deviation of real-time data from the real-time model, and trend analysis (i.e., rate of change) of real-time data. Parameters used are pump pressure, flow rate, torque, rotary speed, hookload and drag, and weight on bit (WOB), along with static inputs such as bottomhole-assembly (BHA) and drillstring configuration and directional surveys. Additional parameters, such as downhole equivalent circulating density (ECD), are used when available and improve the results. But the method is designed to monitor all well types and provide a stuck-pipe-risk log even by use of only basic instrumentation. A novel algorithm predicts the probability of stuck pipe, which is presented in a real-time log.
Results demonstrate that there is no single leading indicator in all stuck-pipe incidents. Our early-detection method, called the stuck-pipe-risk (SPR) log, relies on multiple indicators to strengthen the likelihood of detecting impending stuck pipe while avoiding false alerts. A key element to automating the process is the use of filtering for rig activity. The first indicator is deviation of actual data from model predictions. A second indicator is trend analysis (specifically, rate-of-change calculations), which provides valuable insight into rapidly deteriorating wellbore conditions when deviation from model predictions does not respond quickly enough over a short depth or time interval. Results are presented that show the SPR-detection method successfully detected impending stuck pipe on four historical shale wells an average 38 minutes before sticking and on one historical carbonate well more than 2 hours before the event. No false alerts were recorded in these wells. These results were viewed as meeting the initial goal of providing relevant alerts with sufficient time to prevent the pipe from becoming stuck.
Characterization of Food Product Innovation Practices with Reference to Functional Food Product Development in Singapore
Authors: Khan Rao Sanaullah , Kiat Saw Lin , Grigor John Mark 
Published: May 2017

Functional foods, being one of the major food categories of the global health and wellness market, are becoming a major focus of new product development (NPD) in the food industry. The development of functional foods is more complex than traditional food New Product Development (NPD), calling for a concerted effort from researchers and NPD experts to explore and understand the functional food product development (FFPD) process in more detail.Â The current research in this field has reported that there is a need to evolve from a traditional NPD approach, towards an integrative and innovative approach involving cooperative networks and techniques of commercialization. However, there is little practical evidence on how much progress has been made to date.Â Therefore, this research was designed to investigate the food product innovation process of food manufacturing in the Asia-Pacific region (Singapore) with reference to functional foods development. Results report on a comparative account of NPD practices between registered Singapore food companies that are doing some sort of functional food development (Group 1) and those that are not (Group 2). A significant difference (P<0.05) in the aims and mode of NPD between Group 1 and Group was observed. Further it was observed that food companies in Group 1 have significantly (P<0.05) more diverse external collaborations with broad aims to collaborate, in comparison with food companies in Group 2.Â This is a positive step toward developing an external resource base, which is essential in developing functional foods. This attitude should be encouraged in future innovation polices as being critical to value-added food product innovations in Singapore.Â Apart from these differences, food companies are still pursuing a traditional NPD approach (independent and closed NPD); with loose Intellectual Property protection practices irrespective of type of innovation activity. There is a need to create awareness among the stakeholders about the factors needed for developing unique and inimitable resources, and dynamic capabilities in food manufacturing.Â
Outcome and Clinical Spectrum of Post-streptococcal Glomerulonephritis in Children in Developing Countries
Authors: El-Sayed Saber A. M. , Ali Yasser F. , Ahmady Mostafa M. , Alsayed Salah F. , Baraka Ahmed M. 
Published: May 2017

Background: Post streptococcal glomerulonephritis with crescentic glomerulonephritis is an uncommon outcome in children. This study was done to evaluate the clinical spectrum and outcome in children with crescentic glomerulonephritis following acute post-streptococal glomerulonephritis. The diagnosis of underlying renal disease was based on various criteria, including the clinical picture, serology and histopathology. The patients received treatment in the form of intravenous methyl prednisolone, oral steroid treatment, and oral cyclophosphamide .Objective: to evaluate the clinical spectrum and outcome of the pediatric patients with post-streptococal crescentic glomerulonephritis admitted or referred in Zagazig general hospital in nephrology unit.Â Study design: The study included ( 20 ) children patients with biopsy proven crescentic golmerulonephritis following APSGN admitted or referred from other hospitals to the nephrology unit in Zagazig general hospital between Marsh 2010 to May 2016 These patients were subjected to detailed clinical and biochemical examinations including urine analysis ,U&E ,serum albumin, ASOT ,anti- DNase-B test, complements ( C3 and C4), ANA, ANCAs ,anti- DNA antibodies; anti-(GBM) antibodies . The diagnosis of underlying renal disease was based on various criteria, including the clinical picture, serology and histopathology by light immunofluorescence and electron microscopy and all patients were taken immunosuppressive treatment.Results: 20 patients with poststreptococcal crescentic glomerulonephritis (12 males and 8 females). The mean age of patients at the time of presentation was (7.5) years with range of 5 to 12 years. All were having gross hematuria ,progressive rise of serum creatinine, mean creatinine was 571.5 umol/l with range of (413umol/- 822umol/1) ,low complement C3, 16 patients were having hypertension (80%),10 patients (50%) had nephrotic range of proteinuria and remaining were having moderate range. Renal biopsy which revealed more than 50% crescents in all biopsies with mean of 62.5% and ranging between 50-90%. 4 patients had fibrocellular crescents (20%) and 16 had cellular crescents (80%). the mean follow up duration in months was 25 mo ranging between 22-28 months after immunosuppression,16 patients regained their normal kidney functions (80%) with mean creatinine 47 umol/l ranging between (40-68) P-value <0.001**.4 patients (20%) had residual renal impairment, these 4 patients had fibro cellular crescents in renal biopsy. 8 patients regained their normal blood pressure at last follow up (80%) P-value <0.001**.Conclusion: the overall outcome of 20 patients with post streptococcal crescentic glomerulonephritis was accepted & excellent, 16 patients out of 20 (80%) regained their normal kidney functions. Due to the limited number of our patients , large multi-center study is needed to prove this result.
La gobernanza como modo emergente de gobierno y gestión pública
Authors: Natera Peral Antonio 
Published: May 2017

Si la acción de gobierno era considerada tradicionalmente el núcleo central de la política por su capacidad indiscutida para afrontar los problemas sociales, en la actualidad la política se expresa cada vez más en términos de gobernanza. Hasta hace poco más una década el vocablo «gobernanza» governance se utilizaba precisamente como sinónimoacción de gobierno o de dirección política. Sin embargo, su nuevo atractivo -y la correspondiente extensión semántica- se debe en gran medida a que se ha revelado como una categoría útil para analizar, desde nuevas perspectivas teóricas y metodológicas, la totalidad de instituciones, actores y relaciones implicadas en los procesos de gobierno y de gestión pública, vinculando en un sentido mucho más amplio e integrador el sistema político con su entorno económico y social.
Intracranial pressure monitoring in severe blunt head trauma: does the type of monitoring device matter?
Authors: Aiolfi Alberto , Khor Desmond , Cho Jayun , Benjamin Elizabeth , Inaba Kenji , Demetriades Demetrios 
Published: May 2017

OBJECTIVEIntracranial pressure (ICP) monitoring has become the standard of care in the management of severe head trauma. Intraventricular devices (IVDs) and intraparenchymal devices (IPDs) are the 2 most commonly used techniques for ICP monitoring. Despite the widespread use of these devices, very few studies have investigated the effect of device type on outcomes. The purpose of the present study was to compare outcomes between 2 types of ICP monitoring devices in patients with isolated severe blunt head trauma.METHODSThis retrospective observational study was based on the American College of Surgeons Trauma Quality Improvement Program database, which was searched for all patients with isolated severe blunt head injury who had an ICP monitor placed in the 2-year period from 2013 to 2014. Extracted variables included demographics, comorbidities, mechanisms of injury, head injury specifics (epidural, subdural, subarachnoid, intracranial hemorrhage, and diffuse axonal injury), Abbreviated Injury Scale (AIS) score for each body area, Injury Severity Score (ISS), vital signs in the emergency department, and craniectomy. Outcomes included 30-day mortality, complications, number of ventilation days, intensive care unit and hospital lengths of stay, and functional independence.RESULTSDuring the study period, 105,721 patients had isolated severe traumatic brain injury (head AIS score ≥ 3). Overall, an ICP monitoring device was placed in 2562 patients (2.4%): 1358 (53%) had an IVD and 1204 (47%) had an IPD. The severity of the head AIS score did not affect the type of ICP monitoring selected. There was no difference in the median ISS; ISS > 15; head AIS Score 3, 4, or 5; or the need for craniectomy between the 2 device groups. Unadjusted 30-day mortality was significantly higher in the group with IVDs (29% vs 25.5%, p = 0.046); however, stepwise logistic regression analysis showed that the type of ICP monitoring was not an independent risk factor for death, complications, or functional outcome at discharge.CONCLUSIONSThis study demonstrated that compliance with the Brain Trauma Foundation guidelines for ICP monitoring is poor. In isolated severe blunt head injuries, the type of ICP monitoring device does not have any effect on survival, systemic complications, or functional outcome.