bluuebunny/crossref_metadata_2025_split huggingface dataset:
Late Holocene slip rate and average recurrence interval of great earthquakes on the Shangzhi segment of the Yilan‐Yitong Fault Zone, northeastern China: Constraints from paleo‐earthquakes and historical written records
Authors: Yu Zhongyuan , Zhang Peizhen , Min Wei , Wei Qinghai , Liu Yugang 
Published: November 2017

AbstractThe Yilan‐Yitong Fault Zone (YYFZ) is considered to be the key branch of the Tancheng‐Lujiang Fault Zone (TLFZ) in northeastern China. Although the Mesozoic and early Cenozoic deformation of the YYFZ has been studied intensively over the past century, few estimates of slip rate and recurrence interval of large earthquakes in the late Quaternary, which are the two most important parameters for understanding the potential seismic hazard of this crucial structure, were obtained. Based on integrated interpretations of high resolution satellite images and detailed geologic and geomorphic mapping, linear landforms were identified, including fault scarps and troughs, along the Shangzhi segment of the YYFZ, which exceeds 25 km in length. Synthesized results of trench excavations and differential GPS measurements of terrace surfaces indicate that two events (E1, E2) occurred along the Shangzhi segment during the late Holocene, which resulted in 3.2 ±0.1 m of total vertical co‐seismic displacement with clear features of thrust motion.14C dating of samples suggests that event E1 occurred between 440 ±30 years BP and 180 ±30 years BP and that event E2 occurred between 4 090 ±30 years BP and 3 880 ±30 years BP, which indicates that the minimum vertical slip rate of the Shangzhi segment of the YYFZ has been approximately 0.8 ±0.03 mm/year during the late Holocene. Constraints from paleo events and the slip rate suggest that the average recurrence interval of major earthquakes on the YYFZ is 3 800 ±200 years. Historical documents in Korea show that event E1 possibly corresponds to the earthquake that occurred in AD 1810 (the Qing Dynasty in Chinese history) in the Ningguta area, which had surface‐wave magnitude (Ms) of 6.8–7.5. Studies of kinematics show that the right‐lateral strike‐slip with a reverse component has been dominant along the YYFZ during the late Holocene.
Improving quality of fresh‐cut mango using polysaccharide‐based edible coatings
Authors: Salinas‐Roca Blanca , Guerreiro Ariadna , Welti‐Chanes Jorge , Antunes Maria D. C. , Martín‐Belloso Olga 
Published: November 2017

SummaryThis study was aimed at evaluating the effect of coatings with alginate (AL), pectin (PE), carboxymethyl cellulose (CMC) or chitosan (CH) on microbial stability, physicochemical attributes, total phenolics and carotenoids content, antioxidant capacity and sensory properties of fresh‐cut mango during 14 days at 4 ± 1 °C. Coated fresh‐cut mango kept microbial counts below 6 logs CFU g−1, being CH‐coated fresh‐cut mango those that exhibited the lowest microbial counts (1 log CFU g−1) along entire storage. AL, PE and CMC coatings maintained yellow colour of fresh‐cut mango throughout storage. AL and CH coatings, which have different monomers in their chain, improved the content of antioxidant compounds in fresh‐cut mango as related to uncoated. AL‐coated fresh‐cut mangoes were the toughest, among those coated, during 14 days. The highest consumer acceptance was achieved in AL (90.2%) coated fresh‐cut mango. CH would be the most suitable coating to extend the quality of fresh‐cut mango throughout storage.
Dissecting human ILC heterogeneity: more than just three subsets
Authors: Simoni Yannick , Newell Evan W. 
Published: November 2017

SummaryInnate lymphoid cells (ILCs) have been divided into three distinct groups based on functional capacities, cytokine profiles and transcription factor expression. Studies performed mainly in mice have demonstrated the importance of ILCs in chronic inflammation, infection, allergy and cancer. In this review, we discuss the heterogeneity of human ILC and focus primarily on the taxonomy of human ILC cell subsets and their phenotypical and functional diversity. We summarize recent findings concerning the diversity of ILCs between and within the major subsets [natural killer (NK), ILC1, intra‐epithelial ILC1 (ieILC1), ILC2, ILC3, lymphoid tissues inducer (LTi) and ILC progenitor (ILCP)], as well as the abundance of each in human tissues. We also discuss the similarities observed between groups of cells in term of receptors expressed and cytokines produced, and how these relate to the pleiotropic properties of each subset.
Aluminum‐enhanced alkali diffusion from float glass to PVD‐sputtered silica thin films
Authors: Fonné Jean‐Thomas , Burov Ekaterina , Gouillart Emmanuelle , Grachev Sergey , Montigaud Hervé , Vandembroucq Damien 
Published: November 2017

AbstractInterdiffusion processes between aluminum enriched PVD‐sputtered silica thin films and industrial float soda‐lime silicate glass substrates are quantitatively studied using SIMS analysis. Heat treatments are performed at temperatures close or above the glass transition temperature of the float glass. Aluminum doping of the film is shown to strongly increase the migration of alkali from the glass substrate to the silica thin film. In particular the final alkali content in the film exhibits a linear scaling with the aluminum concentration. An interdiffusion process is evidenced between bulk alkali ions and protons originating from a significant water content in the as‐deposited silica film. Experimental measurements of sodium concentration are shown to be consistent with a simple thermodynamic model based on the equilibration of the activity of sodium between the film and the glass substrate.
Protocol for a new concept of no‐prep ultrathin ceramic veneers
Authors: D'Arcangelo Camillo , Vadini Mirco , D'Amario Maurizio , Chiavaroli Zaccheo , De Angelis Francesco 
Published: November 2017

AbstractObjectivesNo‐prep veneers, although ideally considered the best option because of tooth structure maximum preservation, have been frequently criticized for some potential limitations including esthetic outcomes and periodontal complications.Clinical considerationsA new protocol to optimize no‐prep veneers restorations is presented. A key point of the proposed technique is to identify optimal margins’ positions: margin is positioned in the point of maximum convexity of teeth, avoiding the over contouring of traditional no‐prep veneers.ConclusionThe procedure can be appreciated for the marginal accuracy and the resulting aesthetic stability. The case reports show that properly managed no‐prep veneers can have biologically healthy and aesthetically pleasant tooth‐restoration transitions and emergence profiles.Clinical SignificanceHigh‐quality no‐prep veneers can be more challenging to realize than conventional veneers and the success seems to depend on a combination of good case selection, margins’ position, sound adhesive principles, clinical, and laboratory experience.
Reproductive biology of female striped marlin Kajikia audax in the western Pacific Ocean
Authors: Chang H.‐Y. , Sun C.‐L. , Yeh S.‐Z. , Chang Y.‐J. , Su N.‐J. , DiNardo G. 
Published: November 2017

Length and mass data for 1260 (536 females, 683 males, 41 sex unknown) striped marlin Kajikia audax were collected at the fish markets of Tungkang, Singkang and Nanfangao from July 2004 to September 2010. Of these samples, 534 gonads (236 females and 298 males) ranging from 95 to 206 cm in eye‐to‐fork length (LEF) and 8 to 88 kg in round mass (MR), were collected. Chi‐square tests indicated sex ratios were homogeneous among months in 2004 and 2006–2008, but not in 2005, 2009 and 2010; and there were significant differences in sex ratio by size. The overall sex ratio (RS) differed significantly from the expected 0·5. Kajikia audax are sexually dimorphic and the proportions of females increased with size between 140 and 210 cm LEF. Reproductive activity was assessed using a gonado‐somatic index (IG), external appearance of the gonads and histological examination and results indicated that the spawning season occurred from April to August with a peak in June to July. Based on histological observations and the distribution of oocyte diameters, K. audax are multiple spawners and their oocytes develop asynchronously. The estimated length‐at‐50% maturity (LEF50) was c. 181 cm (c. 4·8 years of age) for females. The proportion of reproductively active females in the spawning season with ovaries containing postovulatory follicles (0·27) indicated that they spawned every 3·7 days on average. The hydrated oocyte method estimated mean ± S.D. batch fecundity (FB) to be 4·4 ± 2·02 million eggs; average relative fecundity was 53·6 ± 13·9 oocytes g−1 MR; and the average annual fecundity was 181·3 ± 48·3 million eggs. The parameters estimated in this study are key information for stock assessments of K. audax in the north‐western and central Pacific and will contribute to the conservation, management and sustainable yield of this species.
Feasibility of intraperitoneal placental‐derived mesenchymal stem cell injection in stomachs of diabetic mice
Authors: Park Jong Min , Lee Sang Hwan , Kim Kwang Il , Kim Won Hee , Cho Joo Young , Hahm Ki Baik , Hong Sung Pyo 
Published: November 2017

AbstractBackground and AimDiabetic gastropathy is associated with loss of interstitial cells of Cajal and autonomic neuropathy. Effective management for diabetic gastropathy is still unavailable. This study was aimed to confirm the pathogenetic changes in diabetic gastropathy and to examine the effect of treatment with placental‐derived mesenchymal stem cells (PDMSCs) in stomachs of animal models.MethodsFourteen non‐obese diabetic/ShiLtJ mice of 8 weeks were bled until week 30. Diabetes mellitus developed in 10 out of 14 mice, which all survived with insulin. The mice were grouped into three groups: nondiabetic group (n = 4), diabetic sham group (n = 5), and diabetic PDMSC group (n = 5) all of which were treated with intraperitoneal PDMSCs injection at week 30. All mice were killed at week 34, and the stomachs were examined by immunohistochemical stain with c‐kit and neuronal nitric oxide synthase antibodies.ResultsThe number of c‐kit positive cells in stomach decreased significantly in the diabetic sham group compared with that in the nondiabetic group (21.2 ± 6.7 vs 88.0 ± 29.3, P = 0.006) but increased with PDMSC treatment (21.2 ± 6.7 vs 64.0 ± 15.1, P = 0.02). The positive rate of neuronal nitric oxide synthase in neural plexus was also significantly lower in the diabetic sham group than in the nondiabetic group (22.3% ± 18.5% vs 48.0% ± 22.7%, P = 0.003) but increased with PDMSC treatment (22.3% ± 18.5% vs 43.3% ± 20.5%, P = 0.03).ConclusionsInterstitial cells of Cajal and neural plexus decreased in stomachs of mice with diabetes mellitus but were significantly repaired with intraperitoneal injection of PDMSC.
Long‐term clinical and echocardiographic outcomes of Mitraclip therapy in patients nonresponders to cardiac resynchronization
Authors: Giaimo Valerio L. , Zappulla Paolo , Cirasa Arianna , Tempio Donatella , Sanfilippo Maria , Rapisarda Giulia , Trovato Danilo , Grazia Angelo Di , Liotta Claudio , Grasso Carmelo , Capodanno Davide , Tamburino Corrado , Calvi Valeria 
Published: November 2017

AbstractObjectivesThis study deals with clinical and echocardiographic outcomes in cardiac resynchronization therapy (CRT) nonresponders patients undergoing Mitraclip procedure.BackgroundFunctional mitral regurgitation (FMR) occurs in approximately one‐third of heart failure (HF) patients. Resynchronization therapy may correct FMR in patients with HF; however, significant FMR persists in 20–25% of CRT patients.MethodsAll patients included were previously treated with CRT for at least 6 months and remained classified as New York Heart Association (NYHA) functional class III or IV despite optimal medical therapy; the echocardiographic assessment showed lack of decrease of the left ventricular end‐systolic volume (LVESV) of at least 10% and residual moderate‐to‐severe or severe FMR. Clinical and echocardiographic follow‐up was scheduled at 1, 3, 6, and 12 months after Mitraclip implantation, and every 6 months thereafter.ResultsThirty patients fulfilled inclusion criteria. Before Mitraclip implantation NYHA class was III in 83% and IV in 17% of patients; after CRT no patient experienced an improvement in FMR. There was a significant improvement in NYHA class from baseline to 6 months, which remained sustained at 12 and 24 months. The degree of FMR significantly improved from baseline to 6 months and from 6 to 12 months. There was left ventricle remodeling with significant reduction of LVESV and an increase of left ventricle ejection fraction at 6 and 12 months, while the opposite trend was noted between 12 and 24 monthsConclusionTreatment of moderate to severe FMR in CRT nonresponder is feasible, safe, and reasonably effective in reducing cardiac symptoms.
Leukocyte adhesion defect‐I: rare primary immune deficiency
Authors: Tewari Nitesh , Mathur Vijay Prakash , Yadav Vikender Singh , Chaudhari Prabhat 
Published: November 2017

ABSTRACTLeukocyte adhesion defect I is a rare disorder (1:1,000,000) caused by diminished expression of CD‐18 β2 integrins on leukocytes leading to abnormal adhesion, migration, and chemotaxis. Clinical manifestations include delayed separation of umbilical cord, omphalitis, recurrent severe infections, impaired wound healing, persistent oral ulcers, and severe periodontitis in primary and permanent dentition.A 5‐year‐old girl, second‐born child to parents with consanguinity, presented with pain and mobility of lower teeth. There was history of recurrent infections and multiple hospital admissions with CD18 level‐3% and frame shift mutation in ITGB2, on 21q22.3. There were scars on hands and feet. Oral examination revealed multiple missing teeth and periodontitis in primary dentition. Oral prophylaxis and palliative treatments were performed with periodic follow‐ups.Interdisciplinary care is ubiquitous for patients with immune deficiencies. Early consultation with pediatric dentists and exploration of medical history is essential for diagnosis and treatment of rare diseases.
Sweat Sodium, Potassium, and Chloride Concentrations Analyzed Same Day as Collection Versus After 7 Days Storage in a Range of Temperatures
Authors: Baker Lindsay B. , Barnes Kelly A. , Sopeña Bridget C. , Nuccio Ryan P. , Reimel Adam J. , Ungaro Corey T. 
Published: November 2017

The purpose of this study was to determine the effect of storage temperature on sodium ([Na+]), potassium ([K+]), and chloride ([Cl−]) concentrations of sweat samples analyzed 7 days after collection. Using the absorbent patch technique, 845 sweat samples were collected from 39 subjects (32 ± 7 years, 72.9 ± 10.5 kg) during exercise. On the same day as collection (PRESTORAGE), 609 samples were analyzed for [Na+], [Cl−], and [K+] by ion chromatography (IC) and 236 samples were analyzed for [Na+] using a compact ion-selective electrode (ISE). Samples were stored at one of the four conditions: −20 °C (IC, n = 138; ISE, n = 60), 8 °C (IC, n = 144; ISE, n = 59), 23 °C (IC, n = 159; ISE, n = 59), or alternating between 8 °C and 23 °C (IC, n = 168; ISE, n = 58). After 7 days in storage (POSTSTORAGE), samples were reanalyzed using the same technique as PRESTORAGE. PRESTORAGE sweat electrolyte concentrations were highly related to that of POSTSTORAGE (intraclass correlation coefficient: .945–.989, p < .001). Mean differences (95% confidence intervals) between PRESTORAGE and POSTSTORAGE were statistically, but not practically, significant for most comparisons: IC [Na+]: −0.5(0.9) to −2.1(0.9) mmol/L; IC [K+]: −0.1(0.1) to −0.2(0.1) mmol/L; IC [Cl−]: −0.4(1.4) to −1.3(1.3) mmol/L; ISE [Na+]: −2.0(1.1) to 1.3(1.1) mmol/L. Based on typical error of measurement results, 95% of the time PRESTORAGE and POSTSTORAGE sweat [Na+], [K+], and [Cl−] by IC analysis fell within ±7–9, ±0.6–0.7, and ±9–13 mmol/L, respectively, while sweat [Na+] by ISE was ±6 mmol/L. All conditions produced high reliability and acceptable levels of agreement in electrolyte concentrations of sweat samples analyzed on the day of collection versus after 7 days in storage.
Oxygen Uptake and Muscle Deoxygenation Kinetics During Skating: Comparison Between Slide-Board and Treadmill Skating
Authors: Piucco Tatiane , Soares Rogério , Diefenthaeler Fernando , Millet Guillaume Y. , Murias Juan M. 
Published: November 2017

Purpose:To compare the oxygen-uptake () kinetics during skating on a treadmill and skating on a slide board and to discuss potential mechanisms that might control thekinetics responses during skating.Methods:Breath-by-breath pulmonaryand near-infrared spectroscopy–derived muscle deoxygenated hemoglobin and myoglobin ([HHbMb]) were monitored continuously in 12 well-trained, young, long-track speed skaters. On-transientand [HHbMb] responses to skating on a treadmill and skating on a slide board at 80% of the estimated gas exchange threshold were fitted as monoexponential function. The signals were time-aligned, and the individual [HHbMb]-to-ratio was calculated as the average value from 20 to 120 s after exercise starts.Results:The time constants for the adjustment of phase II(τ) and [HHbMb] (τ [HHbMb]) were low and similar between slide board and treadmill skating (18.1 [3.4] vs 18.9 [3.6] for τand 12.6 [4.0] vs 12.4 [4.0] s for τ [HHbMb]). Theratio was not different from 1.0 (P > .05) in both conditions.Conclusions:The fastkinetics during skating suggest that chronic adaptation to skating might overcome any possible restriction in leg blood flow during low-intensity exercise. Theratio values also suggest a good matching of O2delivery to O2utilization in trained speed skaters. The similar τand τ [HHbMb] values between slide board and treadmill further reinforce the validity of using a slide board for skating testing and training purposes.
Clinical Measures and Their Contribution to Dysfunction in Individuals With Patellar Tendinopathy
Authors: Jeon Hyunjae , McGrath Melanie L. , Grandgenett Neal , Rosen Adam B. 
Published: November 2017

Context: Patellar tendinopathy (PT) is prevalent in physically active populations, and it affects their quality of living, performance of activity, and may contribute to the early cessation of their athletic careers. A number of previous studies have identified contributing factors for PT; however, their contributions to self-reported dysfunction remain unclear. Objective: The purpose of this investigation was to determine if strength, flexibility, and various lower-extremity static alignments contributed to self-reported function and influence the severity of PT. Design: Cross-sectional research design. Setting: University laboratory. Participants: A total of 30 participants with PT volunteered for this study (age: 23.4 [3.6] y, height: 1.8 [0.1] m, mass: 80.0 [20.3] kg, body mass index: 25.7 [4.3]). Main Outcome Measures: Participants completed 7 different patient-reported outcomes. Isometric knee extension and flexion strength, hamstring flexibility and alignment measures of rearfoot angle, navicular drop, tibial torsion, q-angle, genu recurvatum, pelvic tilt, and leg length differences were assessed. Pearson’s correlation coefficients were assessed to determine significantly correlated outcome variables with each of the patient-reported outcomes. The factors with the highest correlations were used to identify factors that contribute the most to pain and dysfunction using backward selection, linear regression models. Results: Correlation analysis found significant relationships between questionnaires and body mass index (r = −.35–.46), normalized knee extension (r = .38–.50) and flexion strength (r = −.34–.50), flexibility (r = .32–.38, q-angle (r = .38–.56), and pelvic tilt (r = −.40). Regression models (R2 = .22–.54) identified thigh musculature strength and supine q-angle to have greatest predictability for severity in patient-reported outcomes. Conclusions: These findings put an emphasis of bodyweight management, improving knee extensor and flexor strength, and posterior flexibility in PT patients.
Multicenter Evaluation of the Vitek MS v3.0 System for the Identification of Filamentous Fungi
Authors: Rychert Jenna , Slechta E. Sue , Barker Adam P. , Miranda Edwin , Babady N. Esther , Tang Yi-Wei , Gibas Connie , Wiederhold Nathan , Sutton DeAnna , Hanson Kimberly E. 
Published: November 2017

ABSTRACT

Invasive fungal infections are an important cause of morbidity and mortality affecting primarily immunocompromised patients. While fungal identification to the species level is critical to providing appropriate therapy, it can be slow and laborious and often relies on subjective morphological criteria. The use of matrix-assisted laser desorption ionization–time of flight (MALDI-TOF) mass spectrometry has the potential to speed up and improve the accuracy of identification. In this multicenter study, we evaluated the accuracy of the Vitek MS v3.0 system in identifying 1,601 clinical mold isolates compared to identification by DNA sequence analysis and supported by morphological and phenotypic testing. Among the 1,519 isolates representing organisms in the v3.0 database, 91% (
n
= 1,387) were correctly identified to the species level. An additional 27 isolates (2%) were correctly identified to the genus level. Fifteen isolates were incorrectly identified, due to either a single incorrect identification (
n
= 13) or multiple identifications from different genera (
n
= 2). In those cases, when a single identification was provided that was not correct, the misidentification was within the same genus. The Vitek MS v3.0 was unable to identify 91 (6%) isolates, despite repeat testing. These isolates were distributed among all the genera. When considering all isolates tested, even those that were not represented in the database, the Vitek MS v3.0 provided a single correct identification 98% of the time. These findings demonstrate that the Vitek MS v3.0 system is highly accurate for the identification of common molds encountered in the clinical mycology laboratory.