bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of knowledge, attitude and practice (KAP) of pharmacy students’ acceptance of COVID-19 vaccines in South India
Authors: Govindaswamy Swathy , Erakkooth Lakshmi , Sundaram Dhivya P. , Kuppusamy Sujatha , Batcha Abdul kadhar Sathick , Nazeer Mowfiya , Balasubramaniyam Swetha 
Published: October 2024

Purpose: To assess South Indian pharmacy students' knowledge, attitudes and practices (KAP) regarding adherence to COVID-19 immunization guidelines.
Methods: A six-month prospective cross-sectional study was conducted among KMCH College of Pharmacy, Coimbatore pharmacy students. The 39 validated questions on knowledge, attitudes, practices, and concerns about the COVID-19 vaccine were used to grade replies using 3-point and 5- point Likert scales. IBM SPSS Statistics for Windows, Version 23.0, was used to analyze the data.
Results: The survey was completed by a total of 271 pharmacy students. A majority (59 %) of students possessed adequate knowledge (p = 0.0003), and 92 % were willing to receive COVID-19 vaccinations. The majority of respondents have implemented COVID-19-appropriate practices. Majority of information sources (52 %) were from healthcare providers.
Conclusion: Pharmacy students in South India have a fair knowledge of COVID-19 vaccination. More effort is required to improve awareness on this subject.
<i>Oroxylum indicum</i> Kurz (L) leaf extract exerted antioxidant and anti-inflammatory effects on LPS-stimulated BV2 microglial cells
Authors: Mairuae Nootchanat , Buranrat Benjaporn , Yannasithinon Supataechasit , Cheepsunthorn Poonlarp 
Published: October 2024

Purpose: To investigate the antioxidant and anti-inflammatory effects of Oroxylum indicum (L.) Kurz leaf extract on lipopolysaccharide (LPS)-activated BV2 microglia.
Methods: BV2 cells were treated with LPS for 24 h in the presence or absence of Oroxylum indicum (O. indicum) leaf extract. The levels of reactive oxygen species (ROS), nitric oxide (NO), and interleukin 6 (IL-6) were quantified with CM-H2DCFDA, Griess reagent assay, and enzyme-linked immunosorbent assay (ELISA) test, respectively. The antioxidant activity of O. indicum leaf extract was assessed in vitro using DPPH, ABTS and FRAP assays.
Results: Treatment with LPS resulted in significant increases in the levels of ROS, NO, and IL-6, when compared to untreated cells. However, co-treatment with O. indicum leaf extract significantly suppressed the production of these inflammatory markers (p < 0.05). In addition, the leaf extract of O. indicum exhibited antioxidant activity in the DPPH, ABTS, and FRAP assays. The contents of flavonoids and phenolics in O. indicum leaf extract were 13.25 ± 0.163 mg QE/g of dried extract and 82.58 ± 1.772 mg QE/g of dried extract, respectively (p < 0.05).
Conclusion: The leaf extract of O. indicum exhibits anti-inflammatory and antioxidant properties in LPS-activated BV2 cells. This finding indicates that the leaf extract of O. indicum has promising potentials as a new source of herbal medication with anti- inflammatory properties. However, there is a need for more studies to unravel the fundamental mechanisms of their actions.
Effect of intravenous thrombolysis with butylphthalide, edaravone and recombinant tissue plasminogen activator (rt-PA) on serum inflammatory factors in patients with ischemic stroke
Authors: Zhe Xiao , Zhang Shijun , Ren Huiyun 
Published: October 2024

Purpose: To study the impact of edaravone in combination with edaravone and recombinant tissue plasminogen activator (rt-PA) intravenous thrombolysis on serum inflammatory factors in ischemic stroke subjects.
Methods: Eighty ischemic stroke patients in the First Affiliated Hospital of Xi'an Medical University, Xi’an, China were randomly assigned to study and control cohorts, each with 40 subjects. Patients in control cohort were administered edaravone and rt-PA intravenous thrombolysis. The study cohort received butylphthalide in combination with edaravone and rt-PA intravenous thrombolysis. Treatment effectiveness/efficacy, neurological function, self-care ability, inflammatory indicator levels, and blood cell levels were compared between the 2 cohorts.
Results: Efficacy was significantly better in the study cohort than in the control cohort (p < 0.05). After treatment, NIHSS score was significantly lower in the study cohort than in control cohort, while ADL score was significantly higher in the study cohort (p < 0.05). After medication, CRP level was decreased significantly in both cohorts, but was significantly lower level in the study cohort (p < 0.05). Treatment led to significant reductions in white blood cell count, neutrophil count, and NLR ratio in the study cohort, relative to the control cohort (p < 0.05).
Conclusion: The use of butylphthalide in combination with edaravone and rt-PA intravenous thrombolysis produces significant and beneficial effects on ischemic stroke subjects by regulating abnormal levels of inflammatory cells, improving coagulation status and decreasing inflammation. Moreover, it ameliorates neurological defects and improves activities of daily living. There is, however, a need to determine the mechanisms of action of this combination therapy and the influence of other cofounding factors on the activities of the combination therapy.
Adipose-derived mesenchymal stem cells mitigate doxorubicin-induced cardiomyopathy in rats
Authors: Erciyes Demet , Bora Ejder Saylav , Tekindal Mustafa Agah , Arda Duygu Burcu , Erbas Oytun 
Published: October 2024

Purpose: To investigate the effect of adipose-derived mesenchymal stem cells (ADMSCs) on doxorubicin (DOX)-induced cardiomyopathy in rats.
Methods: A total of 30 male Sprague-Dawley rats were randomized into control (n = 10) and study groups (n = 20). Control group received no intervention while the study group received DOX administered intraperitoneally (i.p.) six times daily at a dose of 2.5 mg/kg/ day. The study group was divided into 2 groups. One group received DOX + normal saline (0.9 %w/v) sodium chloride (NaCl) solution ntraperitoneally at a dose of 1 mL/kg/day. Another group received DOX + ADMSC at a dose of 2.0 x 106 cells/kg intraperitoneally twice a week. Biochemical parameters and histopathological changes in blood and heart tissue samples were compared among groups.
Results: Caspase-3 immuno-expression, plasma malondialdehyde (MDA), tumor necrosis factor-α (TNF-α), growth differentiation factor-15 (GDF-15), pro-brain natriuretic peptide (Pro-BNP), troponin, heart transforming growth factor–β (TGF-β) were significantly lower in DOX+ ADMSC compared to DOX + saline group (p < 0.05). However, caspase-3 immune expression and the number of regularly arranged cardiomyocytes significantly decreased in DOX + ADMSC group compared to DOX + saline group (p < 0.05).
Conclusion: Adipose-derived mesenchymal stem cells (ADMSCs) reduce caspase-3 immunoexpression, restore cardiac histology, and ameliorate DOX- induced cardiac injury. Further investigation and clinical trials are recommended, especially to determine the continued safety and efficacy of AD-MSC-based therapy in cardiac injury.
Capítulo 3: LA RESOLUCIÓN DEL RECURSO ESPECIAL EN MATERIA DE CONTRATACIÓN Y ACTOS POSTERIORES
Authors: Gutiérrez González Manuel 
Published: October 2024

SUMARIO: 3.1. LA RESOLUCIÓN DEL REMC 3.1.1. Plazo para la resolución. 3.1.2. Contenido de la resolución. Imposición de multas. 3.1.3. Levantamiento de la suspensión del procedimiento de licitación (47.4 TRLCSP, 31.3 RREMC). 3.1.4. Aclaración de Resoluciones (32 RREMC). 3.1.5. Indemnización de daños y perjuicios (47.3 y 48 TRLCSP, 33 y 36.2 RREMC). 3.2. ACTOS POSTERIORES A LA RESOLUCIÓN DEL RECURSO ESPECIAL EN MATERIA DE CONTRATACIÓN 3.2.1. Emplazamiento de las partes ante los órganos de la jurisdicción Contencioso-Administrativa (artículo 34 RREMC). 3.2.2. Devolución de la documentación (artículo 35 RREMC). 3.2.3. Ejecución de las resoluciones (artículo 49.2 TRLCSP, 36.1 y 2 RREMC). 3.2.4. Incidentes de ejecución (artículo 36.3 RREMC). 3.2.5. Cancelación, devolución y ejecución de garantías (artículo 47.4 TRLCSP, 37 RREMC).
Study of the Association Between Socioeconomic Determinants and Pregnancy Follow-Up Indicators of Mothers of Low-Birth-Weight Infants: Insights for Achieving Sustainable Development Goals
Authors: Bellitir Souhaila , Barkat Assma , Barkat Khalid , Fares Rachid , Chamlal Hamid , Himmi Banacer , Kharbach Aicha , Barkat Amina 
Published: October 2024

Aims: This study investigates the association between socioeconomic determinants and pregnancy follow-up among 200 mothers of low-birth-weight newborns. By identifying factors influencing maternal care and birth outcomes, the study contributes to achieving Sustainable Development Goals (SDG) 3, 8, and 10, focusing on improving maternal and child health, reducing socioeconomic disparities, and ensuring equitable healthcare access.

Methods: A prospective descriptive study was conducted over 12 months (June 2020–July 2021) at the neonatology and nutrition reference center of Rabat Children's Hospital. The study recruited 206 mother-child pairs, focusing on those with low-birth-weight infants.

Results: Among the 200 mothers, 92% followed their pregnancies. Distribution of prenatal consultations was as follows: 0.54% had one visit, 5.98% two visits, 33.7% three, 41.85% four, and 17.93% more than four. Analysis revealed significant associations between pregnancy follow-up and socioeconomic factors. Maternal age (p < 0.001), education level (p < 0.001), and place of residence significantly influenced pregnancy monitoring, with urban mothers more likely to receive follow-up care. Single mothers had a 100% non-tracking rate, while married mothers predominantly monitored their pregnancies.

Conclusions: This study demonstrates the strong influence of sociodemographic factors on antenatal care use, aligning with findings from other contexts. It contributes new insights into the specific characteristics of our study population and has practical implications for shaping maternal and child health policies, addressing the unique needs of diverse sub-populations. Achieving SDG 3 (Good Health and Well-being), SDG 8 (Decent Work and Economic Growth), and SDG 10 (Reduced Inequalities) requires targeted interventions that improve equitable access to quality maternal care.
Analisis Strategi Pengembangan Pemasaran Beras di UD Sri Rejeki Kabupaten Sukoharjo
Authors: Mukson dan  Migie Handayani Yehezkiel Hilkia, 
Published: October 2024

Penelitian ini bertujuan untuk mengidentifikasi faktor-faktor internal dan faktor-faktor eksternal pemasaran produk beras di UD Sri Rejeki, dan menganalisis strategi pengembangan produk beras di UD Sri Rejeki. Penelitian ini dilakukan pada Bulan September – Oktober 2023 di UD Sri Rejeki, Kecamatan Bulu, Sukoharjo, Jawa Tengah. UD Sri Rejeki dipilih sebagai lokasi penelitian secara sengaja (purposive) dengan pertimbangan bahwa UD Sri Rejeki mengolah gabah menjadi produk beras sekaligus memasarkannya ke berbagai wilayah di Sukoharjo. Metode penelitian digunakan studi kasus dengan teknik wawancara menggunakan kuesioner. Sampel menggunakan purposive sampling dengan informan terpilih, terdiri dari pemilik UD Sri Rejeki, 3 orang karyawan, dan 30 orang konsumen langsung, dan 15 agen pemasaran. Metode analisa data digunakan deskriptif kuantitatif dengan analisis SWOT. Metode analisa data digunakan deskriptif kuantitatif dengan analisis Strength, Weakness, Opportunity, and Threat (SWOT). Hasil penelitian menunjukkan bahwa strategi Strength-Opportunity (SO) paling cocok untuk diterapkan dan menghasilkan empat alternatif strategi, yaitu (1) memaksimalkan lokasi strategis dengan pelayanan yang baik, (2) menambah variasi produk yang bervariasi, (3) peningkatan kualitas dan kuantitas produk di UD. Sri Rejeki, (4) peningkatan promosi melalui media sosial.
Analisis Usahatani Jagung (Zea mays, L.) Var. Betras 1 Di Kelompok Tani “Sido Mukti I” Desa Blingoh Kecamatan Donorojo Kabupaten Jepara
Authors: Saparto, dan Harum Sitepu Achmad Jubaidi, 
Published: October 2024

Penelitian ini dilaksanakan di kelompok tani Sido Mukti I Desa Blingoh Kecamatan Donorojo Kabupaten Jepara pada bulan Januari-Maret 2023. Tujuan penelitian adalah untuk mengetahui pendapatan, kelayakan finansial, serta pengaruh biaya sarana produksi (benih, pupuk, pestisida) dan tenaga kerja terhadap pendapatan usaha tani Jagung Betras 1. Metode pengumpulan data dilakukan dengan wawancara yang dipandu kuesioner kepada petani sejumlah 34 orang. Data yang diperoleh dianalisis secara deskriftif. Hasil penelitian menunjukkan bahwa: 1. Pendapatan usahatani jagung varietas Betras 1 rata-rata sebesar Rp. 18.174.912,-/ha/musim tanam, dengan R/C Ratio sebesar 2,4 (≥ 1) , BEP (Q) = 3.145 kg (riil 7.409 kg), BEP (Rp) = Rp. 1.786,- (riil Rp. 4.200,-) dan ROI = 137,3 %; 2. Ada pengaruh yang sangat nyata: biaya sarana produksi (Benih, pupuk, Pestisida) dan Tenaga kerja terhadap pendapatan, dengan persamaan regresi Y = -1865806,324+22,160 X1 ** +9,278 X2 ** -5,855 X3 ns +1,085 X4 ns. (P1%, R2ajst= 0,968). Kesimpulan: Usahatani jagung Betras 1 di Kelompok tani “Sido Mukti I’ Desa Blingoh Kecamatan Donorojo Kabupaten Jepara menguntungkan, layak diusahakan secara finansial, dan secara simultan biaya benih, pupuk, pestisida dan tenaga kerja berpengaruh sangat signifikan terhadap pendapatan usahatani jagung varietas Betras 1, namun secara parsial hanya biaya benih dan pupuk yang berpengaruh secara signifikan terhadap pendapatan usaha tani jagung varietas Betras 1.
Understanding Television Texts
Authors: Wickham Phil 
Published: October 2024

Understanding Television Texts sets out the debates that define television and examines how they can be applied to the study of particular programmes.
How do we respond to what we watch and what affects those responses? Production and consumption contexts are examined, but also the meanings in the texts themselves. In addition, there is a consideration of how technology and social change is transforming our experience of TV. These themes are explored through a range of examples of TV programmes and shows – fact and fiction, contemporary and historical, British and American.
A wide range of case studies are considered – from Planet Earth to Dr Who, The Sopranos to The Apprentice.
Understanding Television Texts emphasises the importance of the active viewer. TV shows are not passive objects that just ‘reflect’ social attitudes; when we watch them we create meanings and make judgments. This book encourages students to consider and develop their own responses, as well as offering an accessible critical overview that equips them for this task.
The intersection of green marketing and sustainable supply chain practices in FMCG SMEs
Authors: Oluwaseun Peter Oyeyemi  , Kikelomo Fadilat Anjorin  , Somto Emmanuel Ewim  , Abbey Ngochindo Igwe  , Ngodoo Joy Sam-Bulya  
Published: October 2024

As sustainability increasingly shapes consumer behavior and corporate strategies, Fast-Moving Consumer Goods (FMCG) small and medium-sized enterprises (SMEs) are adopting green marketing and sustainable supply chain practices to gain a competitive edge. This review explores the intersection of these two critical areas, demonstrating how their integration can drive both business growth and environmental responsibility. Green marketing, which focuses on promoting eco-friendly products and sustainable business practices, has become a key tool for FMCG SMEs to differentiate themselves in a crowded marketplace. By adopting strategies such as eco-friendly packaging, ethical sourcing, and transparency in communicating sustainability efforts, SMEs can build stronger consumer trust, foster brand loyalty, and meet the growing demand for environmentally conscious products. Simultaneously, sustainable supply chain practices ensure that the production, distribution, and logistics processes align with environmental and social goals. These practices include reducing carbon emissions, minimizing waste, and working closely with suppliers to ensure ethical sourcing of materials. The synergy between green marketing and sustainable supply chains creates a feedback loop where operational sustainability supports marketing efforts, and consumer demand for green products encourages further sustainability improvements. This review also examines the challenges FMCG SMEs face in aligning these strategies, such as cost barriers, regulatory compliance, and supply chain complexity. Through case studies and industry examples, it highlights how innovative technology and stakeholder collaboration can help overcome these challenges. Ultimately, this study underscores that integrating green marketing and sustainable supply chain practices is not only essential for addressing environmental concerns but also for enhancing competitive positioning, customer satisfaction, and long-term market success in the FMCG sector. Recommendations for SMEs on how to effectively align their marketing and supply chain sustainability efforts are also provided.
Keywords: Green Marketing, Supply Chain, FMCG SMEs, Review.
PATOLOGIA DO CONCRETO: FISSURAS
Authors: Silva Eduarda Ferreira , Pedreiro Marcelo Rodrigo de Matos 
Published: October 2024

Nos últimos anos o setor da engenharia civil, vem crescendo expansivamente, tornando-se de suma importância para a economia brasileira. E por este fator, são inúmeros os estudos que visem melhorar a estética e a qualidade das edificações. Por esse motivo, as manifestações patológicas devem receber a devida atenção e devem ser cuidadosamente analisadas com o intuito, de oferecer um tratamento ideal. Para tanto, é necessário realizar um diagnóstico exato, no qual se indica em qual etapa do processo construtivo desencadearam-se problemas, apresentando consecutivamente as possíveis correções para estes. Sendo importante, também, instalar medidas de profilaxia que sirvam para evitar o reaparecimento ou a propagação de outras patologias. As fissuras se destacam como uma das principais patologias, pois, são manifestações que se destacam e atraem a atenção dos usuários, gerando na maioria das vezes insegurança, trazendo uma importância negativa nas residências. Portanto, diante de tal importância, o presente trabalho, por meio de uma revisão bibliográfica, teve como objetivo, discorrer sobre os principais tipos de fissuras, suas causas e consequências. Com a realização do mesmo, foi possível concluir a importância do papel do engenheiro civil como algo primordial, pois, este profissional é preparado para realizar um planejamento adequado e consequente acompanhamento técnico, estabelecido o emprego correto de técnicas e a utilização de materiais adequados, garantindo a eficácia e a durabilidade das obras.
Seafloor sediment characterization improves estimates of organic carbon standing stocks: an example from the Eastern Shore Islands, Nova Scotia, Canada
Authors: Brenan Catherine , Kienast Markus , Maselli Vittorio , Algar Christopher K. , Misiuk Benjamin , Brown Craig J. 
Published: October 2024

Abstract. Continental shelf sediments contain some of the largest stocks of organic carbon (OC) on Earth and play a vital role in influencing the global carbon cycle. Quantifying how much OC is stored in shelf sediments and determining its residence time is key to assessing how the ocean carbon cycle will be altered by climate change and possibly human activities. Spatial variations in terrestrial carbon stocks are well studied and mapped at high resolutions, but our knowledge of the distribution of marine OC in different seafloor settings is still very limited, particularly in dynamic and spatially variable shelf environments. This lack of knowledge reduces our ability to understand and predict how much and for how long the ocean sequesters CO2. In this study, we use high-resolution multibeam echosounder (MBES) data from the Eastern Shore Islands offshore Nova Scotia (Canada), combined with OC measurements from discrete samples, to assess the distribution of OC content in seafloor sediments. We derive four different spatial estimates of organic carbon stock: (i) OC density estimates scaled to the entire study region assuming a homogenous seafloor, (ii) interpolation of OC density estimates using empirical Bayesian kriging, (iii) OC density estimates scaled to areas of soft substrate estimated using a high-resolution classified substrate map, and (iv) empirical Bayesian regression kriging of OC density within areas of estimated soft sediment only. These four distinct spatial models yielded dramatically different estimates of standing stock of OC in our study area of 223 km2: 80 901, 58 406, 16 437 and 6475 t of OC, respectively. Our study demonstrates that high-resolution mapping is critically important for improved estimates of OC stocks on continental shelves and for the identification of carbon hotspots that need to be considered in seabed management and climate mitigation strategies.
Spring Issue 2024
Authors: Corbisiero Sophia 
Published: October 2024

SJSHR Spring 2024 | Volume I
Table of Contents
Section I - Socio-Economic Rights
Care to work? Policy Considerations for Engaging Jordanian Women in the Workforce by Elizabeth Hudler
Dilemma between Economic Incentives and the Public Provision of Welfare:SER Trade-offs in China’s economic development and its healthcare reforms, 1979~2022 by Yutong Zheng
Providing Health Care but Receiving None in Return:An Expanded Right to Health Analysis of the Live-In Caregiver Program of Canada (1992-2014) by Claire Ellis
Revising the ICESCR’s individual complaint mechanism: the transformative potential of a right to a “dignified minimum existence” for the CESCR’s standards of review by Clémence Françoise Roy
Section II - Indigenous Peoples Rights
Lack of rights: Indigenous Peoples in French Guiana by Elliot Mur
The Intersectionality of Conflicts in Micronesia and Hawaii: Through My Eyes by Ed Yeichy
An evaluation of activities and intervention approaches in an acute dementia setting
Authors: Gordon-Brown Alexandra , Sawyer Laura , Evans Kirby , Neilan Natasha , Tebby Katie , Martin Kate 
Published: October 2024

Background:Recommended interventions for dementia prioritises person-centred care and non-pharmacological approaches. The evidence-base for various therapies such as Cognitive Stimulation Therapy (CST), music therapy and sensory based interventions has been growing in recent years; however, there is limited guidance surrounding best practice for working with advanced dementia in acute settings, and research regarding the evaluation of ward interventions is scarce.Method:An audit checklist was compiled from the current recommendations and evidence base. Observations of structured activity sessions were conducted across two acute dementia wards to identify how well these aligned with evidence-based recommendations.Results:Our results suggest that activity sessions on the wards align to the evidence base. Specifically, the wards offer high quality interventions integrating CST approaches. It was revealed that the capturing of these interventions was limited within the clinical notes systems, and an action plan to facilitate efficient capturing was identified and initiated.Conclusion:The study found that it is possible to offer evidence-based activity sessions in an acute setting, for patients with typically advanced dementia presentations. Staff feedback led to the production of a poster to help staff identify the interventions they implicitly use as part of their role, aiming to encourage staff to be proud of their work on the ward and be more aware of evidence-practice links.