bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects and prevalence of nonresponders after 12 weeks of high-intensity interval or resistance training in women with insulin resistance: a randomized trial
Authors: Álvarez Cristian , Ramírez-Campillo Rodrigo , Ramírez-Vélez Robinson , Izquierdo Mikel 
Published: February 2017

Our aim was to investigate the effects and prevalence of nonresponders (NR) to high-intensity interval training (HIIT) and resistance training (RT) in women with insulin resistance on cardiometabolic health parameters. Sedentary overweight/obese insulin-resistant women (age = 33.5 ± 6.5 yr; body mass index = 29.9 ± 3.7 kg/m2) were randomly assigned to a triweekly HIIT program (HIIT; n = 18) or resistance training (RT; n = 17). Anthropometry (body mass, fat mass, muscle mass, waist circumference, and skinfold thickness), cardiovascular (blood pressure), metabolic [fasting glucose, fasting insulin, and homeostatic model of insulin resistance (HOMA-IR)], as well as muscle strength, and endurance performance covariables were measured before and after 12 wk in both intervention groups. The interindividual variability to exercise training of the subjects was categorized as responders and NR using as cut points two times the typical error of measurement in mean outcomes. After intervention, significant reduction in waist circumference, skinfold thicknesses, fat mass, blood pressure, fasting glucose, insulin, and HOMA-IR ( P < 0.05) were identified to HIIT and RT group, respectively. Both HIIT and RT groups exhibited a significant decrease in the endurance performance, whereas only RT exhibited increased muscle strength. Significant differences in the NR prevalence between the HIIT and RT groups were identified for a decrease in fat mass (HIIT 33.3% vs. RT 70.5%; P = 0.028), muscle mass (HIIT 100% vs. RT 52.9%; P = 0.001), and tricipital skinfold (HIIT 5.5% vs. RT 29.4%; P < 0.041). For diastolic blood pressure, significant differences were observed in the NR prevalence between the HIIT and RT groups (55.5% vs. 94.1; P = 0.009). However, there were no differences in the NR prevalence between HIIT and RT for decreasing fasting glucose. Twelve weeks of HIIT and RT have similar effects and NR prevalence to improve glucose control variables; however, there is different NR prevalence in other anthropometric, cardiovascular, strength, and endurance performance measurements in insulin-resistant women. These findings were displayed with a similar time investment per week of 114 vs. 108 min, respectively, to HIIT and RT. NEW & NOTEWORTHY The effects and prevalence of nonresponders (NR) to improve glucose control variables have predominately been reported by endurance training. A uniqueness of the present study was to examine the NR prevalence in women with insulin resistance after high-intensity interval (HIIT) and resistance training (RT). This study demonstrates that 12 wk of HIIT and RT have similar effects and NR prevalence to improve glucose control variables. However, significantly different NR prevalence were observed in other anthropometric, cardiovascular, strength, and endurance performance measurements.
EKG Electrode as a Tactile Locator of Stoma after Decannulation
Authors: Garcia‐Rodriguez Laura , Miah Tayaba , Lindholm Jamie , Chang Steven , Ghanem Tamer 
Published: February 2017

ObjectiveWe aimed to evaluate the use of an electrocardiogram (EKG) electrode over decannulation dressings covering the stoma to improve speech intelligibility and volume and reduce air escape by facilitating identification of the “sweet spot” of the dressing. No objective data exist for patient outcomes with use of the EKG electrode dressing.MethodsThis prospective study included head and neck oncology patients at a tertiary hospital who received a tracheostomy. A standard tracheostomy decannulation dressing was placed followed by an EKG electrode. A speech pathologist evaluated speech volume via sound‐level meter and captured speech intelligibility for random sentence‐level speech. A blinded reviewer scored speech samples for intelligibility. Patients completed a 4‐question satisfaction survey.ResultsFour patients completed the study. Based on the survey, the patients favored the button, with the lowest scores being 8.5 out of 10. Speech understanding was 48.5% without the button and 83% with the button. Normal speech volume was 73.75 dB without the button and 77.75 dB with the button. Loud speech volume was 80.75 dB without the button and 87 dB with the button.DiscussionThis pilot study shows objective benefits of the EKG button as well as improved patient satisfaction. Inexpensive and low maintenance, the EKG electrode provides better occlusion of stoma dressing with easier localization.Implications for PracticeDissemination of our results will aim to improve quality and patient outcomes following decannulation.
Management of the first episode of traumatic shoulder dislocation
Authors: Boffano Michele , Mortera Stefano , Piana Raimondo 
Published: February 2017

Shoulder joint dislocation is the most common joint dislocation seen in the emergency department. Traumatic dislocation may cause damage to the soft-tissues surrounding the shoulder joint and sometimes to the bone. The treatment, which aims at restoration of a fully functioning, pain-free and stable shoulder, includes either conservative or surgical management preceded by closed reduction of the acute dislocation. Conservative management usually requires a period of rest, generally involving immobilisation of the arm in a sling, even though it is still debated whether to immobilise the shoulder in internal or external rotation. Operative management, with no significant differences in term of re-dislocation rates between open and arthroscopic repair, incorporates soft-tissue reconstructions and/or bony procedures and is recommended in young male adults engaged in highly demanding physical activities. At our institution, non-operative management is favoured particularly for patients with multi-directional instability or soft-tissue laxity. Conservative measures are often preferred in older patients or younger patients that are not actively engaged in overhead activities. Immediate surgery on all first-time dislocations may subject many patients to surgery who would not have had any future subluxation. For these reasons, initially we will always try physical therapy and activity modification for the vast majority of our patients. Cite this article: EFORT Open Rev 2017;2:35-40.DOI: 10.1302/2058-5241.2.160018.
Mechanistic-Empirical Asphalt Pavement Design Considering the Effect of Seasonal Temperature Variations
Authors: Haponiuk B. , Zbiciak A. 
Published: February 2017

AbstractThe paper analyses the influence of seasonal temperature variations on fatigue strength of flexible and semi-rigid pavement structures chosen for KR4 traffic flow category. The durability of pavement determined assuming a yearly equivalent temperature of 10°C and assuming season-dependent equivalent temperatures was compared. Durability of pavement was determined with the use of Asphalt Institute Method and French Method. Finite Element Method was applied in order to obtain the strain and stress states by the means of ANSYS Mechanical software. Obtained results indicate a considerable drop in pavement durability if seasonal temperature variations are considered (up to 64% for flexible pavements and up to 80% for semi-rigid pavements). Durability obtained by the French Method presents lower dependence on the analysed aspect.
Analyse of the Challenges for Safe Transition from Individual Intraoperable Railway Systems to the Single European Interoperable Railway System
Authors: Pawlik M. 
Published: February 2017

AbstractDue to different reasons a significant modal shift from railway to road transport took place over last decades. The basic reasons are pointed in the paper introduction together with contradicting transport policy taking into account environmental and economical challenges. Political vision to stimulate modal shift from road and air to railway cannot become true without achieving railway technical and operational interoperability. Paper describes wide range of technical barriers between individual intraoperable railway systems in civil engineering structures, traction power supply, control command and signalling and the ways, which are being applied to ensure stepwise converging of the technical solutions taking into account safety and technical compatibility, as well as other essential requirements, namely: reliability, accessibility, health and environment.
Split-Step Timing of Professional and Junior Tennis Players
Authors: Filipcic Ales , Leskosek Bojan , Filipcic Tjasa 
Published: February 2017

Abstract
The purpose of the study was to determine the timing of a split-step in three categories of tennis players in four groups of strokes. Subjects were divided into three groups: male and female junior, and male professional tennis players. During two tournaments, all matches were recorded with two fixed video cameras. For every stroke, the timing of the split-step between the opponent’s impact point when hitting the ball and the player’s split-step was measured. A two-way analysis of variance (ANOVA) was used to determine the differences between groups of strokes, players and the interaction Player x Stroke Group. A Tukey post-hoc test was employed to determine specific differences. The results revealed differences between players in detecting the opponent’s movement, stroke and ball flight, which were reflected in different split-step timings. Each tennis player has his/her own timing mechanism which they adapt to various game situations. Response times differ significantly depending on the game situation. On average, they are the lowest in the serve, and then gradually rise from the return of the serve to baseline game, reaching the highest values in specific game situations. Players react faster in the first serve than in the second one and in the return of the serve, the response times are lower after the return of the second serve
Optimal Decentralized Supplementary Inverter Control Loop to Mitigate Instability in an Islanded Microgrid with Active and Passive Loads
Authors: Raju P. E. S. N. , Jain Trapti 
Published: February 2017

Abstract:
The growing penetration levels of passive and rectifier interfaced active loads can cause instability in an islanded inverter based microgrid. This may be due to the dynamics associated with passive loads and interaction between the control loops of active loads and inverter-interfaced DGs. This paper proposes a decentralized supplementary control loop around each inverter-interfaced distributed generation (DG) unit to mitigate the instability caused by both the active as well as passive loads. The proposed control loop is based on a robust linear quadratic regulator with prescribed degree-of-stability (LQRPDS). In order to obtain the optimal values of the state and control weighting matrices of LQRPDS, a bi-objective optimization problem has been formulated and solved using a fast and elitist multi-objective non-dominated sorting genetic algorithm (NSGA-II). The proposed decentralized supplementary
control loop does not interfere with the steady state performance and provides robust control performance under various load configurations as well as step load disturbances. Eigenvalue analysis and time-domain simulations have been used to validate the effectiveness of the proposed decentralized supplementary control loop.
Optical Modulation Enhancement Through CW Injection Locking of a Sinusoidally Modulated Fabry-Perot Laser Diode
Authors: Chakraborty Meenakshi , Chattopadhyay Taraprasad 
Published: February 2017

Abstract
This paper reports an interesting phenomenon of optical modulation enhancement produced by CW optical sideband injection locking of a directly modulated Fabry-Perot Laser Diode (FPLD) lasing at 1557.1 nm wavelength, the modulation being sinusoidal in nature and effected at 300 kHz and 3 MHz. This investigation is carried out for direct modulation of the FPLD effected in the RF region at 300 kHz and 3 MHz in contradistinction to earlier studies being conducted with the modulation in the microwave frequency band. A nonlinear analysis has been carried out which corroborates experimental observation on modulation enhancement. At low level of optical Intensity Modulation (IM) index, not exceeding 20 %, typical modulation enhancement of 2 % at 300 kHz and 11 % at 3 MHz modulation frequency have been observed. Larger modulation enhancement is expected at higher values of IM indices of the slave FPLD and for medium to high power laser diodes. This circuit can have direct application in Wavelength Division Multiplexed-Passive Optical Network (WDM-PON).
Distanciamiento ilustrado en las argumentaciones deconstructoras de Rousseau
Authors: Higuero Francisco Javier 
Published: February 2017

En conformidad con lo explicado por Jean-Jacques Rousseau a lo largo de su producción filosófica, el estado ideal de la naturaleza no sólo se define como anterior a categorizaciones lingüísticas, sino que, hasta cierto punto, ha sido romantizado por diversos críticos, abocados a presentar las ideas de dicho pensador como marcadamente alejadas de la premisas y propuestas esgrimidas por el movimiento cultural de la Ilustración. Tal estado originario de la naturaleza se presta a ser considerado como pacífico, harmónico, vacío de envidia y prelingüístico o silencioso. En semejantes circunstancias, el habitante de tal entorno natural se aproximaba al mundo directamente y sin las fisuras producidas por elucubraciones culturales, provenientes de dictámenes civilizatorios. Sin embargo, la teoría de la voluntad general, defendida por Rousseau en El contrato social, desarrolla estrategias argumentativas dirigidas a superar el aislacionismo congénito al habitante del estado de la naturaleza, intentando deconstruir la dicotomía binaria que enfrentaba a la abstracta racionalidad ilustrada con la inmediatez de la experiencia primigenia. Wayne State University, Detroit, USA
Oral Administration of Methylphenidate (Ritalin) Affects Dopamine Release Differentially Between the Prefrontal Cortex and Striatum: A Microdialysis Study in the Monkey
Authors: Kodama Tohru , Kojima Takashi , Honda Yoshiko , Hosokawa Takayuki , Tsutsui Ken-ichiro , Watanabe Masataka 
Published: February 2017

Methylphenidate (MPH; trade name Ritalin) is a widely used drug for the treatment of attention deficit hyperactivity disorder (ADHD) and is often used as a cognitive enhancer. Because MPH increases dopamine (DA) release by blocking the DA transporter in the human striatum, MPH is supposed to work on attention and cognition through a DA increase in the striatum. However, ADHD patients show impaired prefrontal cortex (PFC) function and MPH administration is associated with increased neural activity in the PFC. Although MPH is indicated to increase DA release in the rat PFC, there has been no study to examine MPH-induced DA changes in the human PFC because of technical difficulties associated with the low level of PFC DA receptors. Using the microdialysis technique, we examined the effects of oral administration of MPH on DA release in both the PFC and striatum in the monkey. We also tested the effect of MPH on cognitive task performance. As in human studies, in the striatum, both high and low doses of MPH induced consistent increases in DA release ∼30 min after their administrations. In the PFC, a consistent increase in DA release was observed 1 h after a high dose, but not low doses, of MPH. Low doses of MPH improved cognitive task performance, but a high dose of MPH made the monkey drowsy. Therefore, low-dose MPH-induced cognitive enhancement is supported by striatum DA increase.SIGNIFICANCE STATEMENTMethylphenidate (MPH) is a widely used drug for the treatment of attention deficit hyperactivity disorder and is often used as a cognitive enhancer. Although human positron emission tomography studies suggest that MPH works on attention and cognition through dopamine (DA) changes in the striatum, there has been no study to examine MPH-induced DA changes in the human prefrontal cortex (PFC). Using the microdialysis technique in monkeys, we found, for the first time, that low doses of MPH consistently increased DA release in the striatum but did not in the PFC. Cognitive enhancement effects of low doses of MPH are supposed to be supported by the striatum DA increase.
The Coupling between Ca2+Channels and the Exocytotic Ca2+Sensor at Hair Cell Ribbon Synapses Varies Tonotopically along the Mature Cochlea
Authors: Johnson Stuart L. , Olt Jennifer , Cho Soyoun , von Gersdorff Henrique , Marcotti Walter 
Published: February 2017

The cochlea processes auditory signals over a wide range of frequencies and intensities. However, the transfer characteristics at hair cell ribbon synapses are still poorly understood at different frequency locations along the cochlea. Using recordings from mature gerbils, we report here a surprisingly strong block of exocytosis by the slow Ca2+buffer EGTA (10 mM) in basal hair cells tuned to high frequencies (∼30 kHz). In addition, using recordings from gerbil, mouse, and bullfrog auditory organs, we find that the spatial coupling between Ca2+influx and exocytosis changes from nanodomain in low-frequency tuned hair cells (∼<2 kHz) to progressively more microdomain in high-frequency cells (∼>2 kHz). Hair cell synapses have thus developed remarkable frequency-dependent tuning of exocytosis: accurate low-latency encoding of onset and offset of sound intensity in the cochlea's base and submillisecond encoding of membrane receptor potential fluctuations in the apex for precise phase-locking to sound signals. We also found that synaptic vesicle pool recovery from depletion was sensitive to high concentrations of EGTA, suggesting that intracellular Ca2+buffers play an important role in vesicle recruitment in both low- and high-frequency hair cells. In conclusion, our results indicate that microdomain coupling is important for exocytosis in high-frequency hair cells, suggesting a novel hypothesis for why these cells are more susceptible to sound-induced damage than low-frequency cells; high-frequency inner hair cells must have a low Ca2+buffer capacity to sustain exocytosis, thus making them more prone to Ca2+-induced cytotoxicity.SIGNIFICANCE STATEMENTIn the inner ear, sensory hair cells signal reception of sound. They do this by converting the sound-induced movement of their hair bundles present at the top of these cells, into an electrical current. This current depolarizes the hair cell and triggers the calcium-induced release of the neurotransmitter glutamate that activates the postsynaptic auditory fibers. The speed and precision of this process enables the brain to perceive the vital components of sound, such as frequency and intensity. We show that the coupling strength between calcium channels and the exocytosis calcium sensor at inner hair cell synapses changes along the mammalian cochlea such that the timing and/or intensity of sound is encoded with high precision.
Potential objective biomarkers for fatigue among working women
Authors: Ebata Chie , Tatsuta Hitomi , Tatemichi Masayuki 
Published: February 2017

Abstract

Objective
The prediction of health impairment due to work overload is subjectively assessed based on recognized symptoms; however, objective evaluation is primarily ideal in the field of occupational health. Recently, some biomarkers of autonomic function and/or oxidative stress were reported to be associated with fatigue. This study aimed to preliminarily investigate whether these biomarkers could be objective indicators for fatigue and stress among working women.

Method
Participants included 118 full-time female workers (mean age 37.8 years), including 55 shift workers. Selfadministered questionnaires, such as visual analog scale (VAS) for general health, a lifestyle questionnaire, SF-8 for health-related quality of life, and K6 for mental health screening, were used. In addition, biomarkers such as acceleration plethysmogram (APG), reactive oxygen metabolites-derived compounds (d-ROMs), and biological antioxidant potential (BAP) were measured.

Results
A significant association was observed between BAP and VAS (r=0.482, p&lt;0.01) among shift workers. However, other biomarkers such as APG and d-ROMs were not significantly associated with symptoms. d-ROMs were significantly correlated with age and body mass index. There was a significant negative correlation between BAP and smoking. Results of the APG (lowfrequency (LF)/high-frequency (HF) ratio) were significantly correlated with BAP, but not with d-ROMs. The LF/HF ratio and BAP for shift workers were significantly higher than those for day-time workers.

Conclusions
Our results suggest that APG and BAP are potential objective biomarkers for fatigue among working women, although further follow-up studies are needed to clarify the scope of usefulness of the biomarkers for fatigue.
Conductive Polymer/Transition Metal Oxide Hybrid Materials for Lithium Batteries
Authors: Kwon Chai-Won , Poquet Armel , Mornet Stéphane , Campet Guy , Portier Josik , Murugan A. Vadivel , Kale B. B. , Vijayamohanan K. , Choy Jin-Ho 
Published: February 2017

AbstractOrganic-inorganic hybrid materials were synthesized for use of lithium battery electrode by two strategies: 1) core-shell strategy for tri-dimensional transition metal oxide and 2) intercalation strategy for bi-dimensional (lamellar) transition metal oxide. We choose conductive polymers as an organic component for high electric conductivity and 3d-transition metal oxides as an inorganic counterpart for large capacity and processibility. Polypyrrole/maghemite and poly(3,4-ethylenedioxythiophene) (PEDOT)/vanadium pentoxide hybrids will be presented and compared with their pristine materials for core-shell and intercalation strategies, respectively. Polypyrrole/maghemite showed an enhanced electrochemical reversibility and capacity up to ∼270 mAh/g in the potential range between 1.3 and 4.3 V vs. Li at 8 mA/g. PEDOT/vanadium pentoxide also exhibited improved reversibility and capacity up to ∼330 mAh/g at 15 mA/g between 2.0 ∼ 4.4 V vs. Li on the second discharge. XRD, IR, electron microscopy, XPS and Xray absorption spectroscopy were used to characterize the samples, and to examine oxidation state of the transition metals, doping character of the polymer and the nature of interaction between the polymer and the transition metal oxides.
Development of Porous Polymer-Ceramic Composites as Bone Grafts
Authors: Kalita Samar , Finley John , Bose Susmita , Hosick Howard , Bandyopadhyay Amit 
Published: February 2017

AbstractBiomaterials have made significant contributions to the advancement of modern health care and drug delivery industries. The present research is based on development of porous polymerceramic composite scaffolds using polypropylene (PP) polymer and tricalcium phosphate (TCP) ceramic for bone-graft applications. Three dimensionally interconnected controlled porosity scaffolds were fabricated using a fused deposition modeling (FDM) system. First, ceramic and polymeric materials were compounded under high shear using a torque rheometer. Compounded materials were then extruded to a 1.78mm diameter continuous filament using a single screw extruder. These filaments were used as a feedstock material for an FDM 1650 machine for direct fabrication of controlled porosity parts. Hg-porosimetry was done to determine pore size and their distribution in these structures. Tensile properties of neat composites and as received polymer were measured and compared using standard dog bone samples. Uniaxial compression tests were performed on cylindrical porous samples having average pore size of 160 μm and 36 vol% porosity. These samples showed an average ultimate compressive strength of 12.7 MPa. Average compressive modulus was calculated as 263 MPa. Cytotoxicity and cell proliferation studies were conducted with OPC1 modified human osteoblast cell-line. It was found that composite matrices were non-toxic and they showed excellent cell growth with OPC1 cells.