bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uterine Artery Doppler Velocimetry for the Prediction of Preeclampsia among High-risk Pregnancies in Low-resource Setting: Our Experience at Aminu Kano Teaching Hospital, Kano, Nigeria
Authors: Dayyabu Aliyu L , Yusuf Murtala , Galadanci Hadiza , Ismail Anas , Danbatta Abdu H 
Published: November 2017

ABSTRACT
Several Doppler studies have demonstrated an association between increased impedance to flow in uterine arteries and subsequent development of preeclampsia. This study evaluated the usefulness of uterine artery Doppler velocimetry in the prediction of preeclampsia in high-risk pregnancies.
The study was a prospective cohort study carried out on 138 pregnant women attending antenatal clinic in Aminu Kano Teaching Hospital, a tertiary center in Northern Nigeria. Assessment of uterine artery blood flow by Doppler ultrasound was carried out at 20 to 24 weeks of gestation. The test was considered abnormal when the mean resistance index (RI) in the uterine arteries was .0.58 with or without diastolic notch (DN). The women were then followed up to determine those who developed preeclampsia.
The prevalence of preeclampsia in this study was found to be 12.3%. Twenty one of the patients (15.2%) had high uterine artery RI (. 0.58), while 117 (84.8%) had normal RI (<0.58). The prevalence of preeclampsia was significantly higher (p < 0.05) in the group with high RI than in the group with normal RI (57.1 compared with 4.2%). Nine of the patients (6.5%) had DN, while 129 (93.5%) had no DN. The prevalence of preeclampsia was also significantly higher (p < 0.05) in the group with DN than in the group with no DN (55 compared with 9.3%). Both the sensitivity (70.5%) and specificity (92.6%) of abnormal RI in the prediction of preeclampsia were found to be high.
This study confirmed the efficacy of second trimester screening for preeclampsia in high-risk pregnancies using a combination of maternal characteristics and uterine artery Doppler.

How to cite this article
Yusuf M, Galadanci H, Ismail A, Aliyu LD, Danbatta AH. Uterine Artery Doppler Velocimetry for the Prediction of Preeclampsia among High-risk Pregnancies in Low-resource Setting: Our Experience at Aminu Kano Teaching Hospital, Kano, Nigeria. Donald School J Ultrasound Obstet Gynecol 2017;11(3):197-202.
The Fetal Thorax
Authors: Bozanovic Tatjana , Ljubic Aleksandar 
Published: November 2017

ABSTRACT
Although relatively uncommon, congenital abnormalities in the thorax are important because of the potential effect on lung growth as well as the effect of the intrinsic abnormality.

How to cite this article
Ljubic A, Bozanovic T. The Fetal Thorax. Donald School J Ultrasound Obstet Gynecol 2017;11(3):210-224.
Advances in Fetal Neuroimaging
Authors: Vladareanu Radu , Panchal Sonal , Berceanu Costin , Bot Mihaela 
Published: November 2017

How to cite this article
Hata T. Fetal Neuroimaging. Donald School J Ultrasound Obstet Gynecol 2017;11(3):233-243.

How to cite this article
Panchal S. Fetal Neuroimaging. Donald School J Ultrasound Obstet Gynecol 2017;11(3):244-248

How to cite this article
Vlãdãreanu R, Berceanu C, Bot M, Vlãdãreanu S. Neurosonography. Donald School J Ultrasound Obstet Gynecol 2017;11(3):249-258
A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup
Authors: Babu S Vinod , Jagadeesan Anusha R , Ramalingam Jothimalar 
Published: November 2017

ABSTRACT

Introduction
Obesity is emerging as an epidemic worldwide. Obesity is associated with a number of comorbid conditions, such as diabetes mellitus, hypertension, cancer, dyslipidemia, cardiovascular abnormalities, anemia, obstructive sleep apnea, and psychosocial abnormalities.

Aim
This study aims at comparing the lipid profile levels of obese and nonobese men.

Materials and methods
This was a case—control study conducted at a tertiary care center. Totally, 80 men in the age group of 20 to 47 years attending the master health checkup were included in the study, out of which 40 men with normal body mass index (BMI) of 18 to 25 belonged to group I and 40 men with increased BMI of 30 and above belonged to group II. Lipid profile parameters, such as triglycerides (TGLs), total cholesterol, high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were estimated in them. The data were statistically analyzed using Statistical Package for the Social Sciences (SPSS) software version 15.0.

Results
Statistically significant difference was found in the total cholesterol levels with a p-value of 0.040 while the difference in LDL cholesterol was statistically highly significant with a p-value of 0.040.

Conclusion
Among lipid profile parameters, only total cholesterol and LDL cholesterol showed significant difference between the obese and nonobese individuals. However, the other parameters like HDL cholesterol and TGLs did not show any significant difference.

How to cite this article
Babu SV, Jagadeesan AR, Ramalingam J. A Comparative Study of Lipid Profile in Obese and Nonobese Men attending Master Health Checkup. Indian J Med Biochem 2017;21(2):73-75.
Comparison of measured Serum Total Carbon Dioxide with calculated Bicarbonate calculated from Arterial Blood Gas Analysis
Authors: Mohan Thuthi , Kumar B Vinodh 
Published: November 2017

ABSTRACTIntroductionMeasured total carbon dioxide (TCO2) from venous sample and calculated bicarbonate from arterial blood gas (ABG) have shown good agreement in some studies, while conflicting results have been obtained in few other studies. The objective of this study is to compare and assess the degree of agreement between the measured TCO2and calculated bicarbonate and also whether they can be used interchangeably in our laboratory.Materials and methodsWe prospectively analyzed 89 ABG samples requested for calculated bicarbonate and then measured TCO2from venous blood samples drawn simultaneously from the same participants between November 2016 and April 2017.ResultsMeasured TCO2results ranged from 5.7 to 39.9 mmol/L (mean 23.45 mmol/L), while calculated bicarbonate ranged from 9 to 40 mmol/L (mean 24.36 mmol/L). The values of TCO2and bicarbonate correlated well (r = 0.95, p < 0.001), with the correlation given by the equation, y = 0.884x+ 3.605. The bias obtained was —0.9 mmol/L and the standard deviation (SD) was 1.62 mmol/L. The limits of agreement (LOA) were —4.1 to 2.3 mmol/L, with a span of 6.4 mmol/L. Out of the 89 values, 85 (95.05%) were within the LOA.ConclusionIn majority of the cases, the calculated bicarbonate concentration from ABG showed a good correlation to the measured venous TCO2concentration. Despite this excellent correlation, TCO2did not show good agreement with calculated bicarbonate when Story and Poustie's criteria were applied, especially in cases of bicarbonate less than 20 mmol/L. Hence, clinicians should be aware of this discrepancy and be cautious when using measured TCO2and calculated bicarbonate interchangeably in the assessment and management of acid—base disorders, especially in patients with metabolic acidosis.How to cite this articleMohan T, Kumar BV. Comparison of measured Serum Total Carbon Dioxide with calculated Bicarbonate calculated from Arterial Blood Gas Analysis. Indian J Med Biochem 2017;21(2):76-80.
Metabolic Derangement in Birth Asphyxia due to Cellular Injury with Reference to Mineral Metabolism in Different Stages of Hypoxic-ischemic Encephalopathy in Central India
Authors: Vamne Amrita , Bhimte Bhawna 
Published: November 2017

ABSTRACT

Introduction
Perinatal asphyxia is one of the major causes of neonatal mortality and long-term morbidity. Although neonates with severe birth asphyxia are known to be at increased risk of early-onset hypocalcemia, the magnitude of the problem is not well documented. Magnesium plays a role in neuroprotection for neonates with hypoxic-ischemic encephalopathy (HIE). The objective of this study was to determine the prevalence of early-onset hypocalcemia and hypomagnesemia in severely asphyxiated neonates.

Materials and methods
This study was carried out on 75 newborns distributed as group I (50 asphyxiated neonates) and group II (25 healthy neonates). Serum calcium and serum magnesium was estimated within 24 hours after birth, followed by third and fifth day postbirth.

Results
Maximum number of cases (81.3%) were born by vaginal delivery. The mean value of serum calcium on days 1, 3, and 5 for group I was 7.004 ± 0.691, 7.482 ± 0.760, 8.184 ± 0.811 in contrast to group II: 8.788 ± 0.399, 9.476 ± 0.250, 9.992 ± 0.277 respectively. Whereas the mean value of serum magnesium for group I is reported as 1.545 ± 0.045, 1.496 ± 0.067, 1.556 ± 0.057 on days 1, 3, and 5, while that of group II was 1.518 ± 0.053, 1.597 ± 0.049, 1.66 ± 0.065 respectively. On HIE stage-wise comparison, abnormal calcium metabolism percentage increases with severity of asphyxia (46.6% abnormal in stage I, while 71.4% abnormal in stage III). Abnormal magnesium metabolism percentage also increases with severity of asphyxia (26.6% abnormal in stage I, while 71.4% abnormal in stage III) and this abnormality persists up to fifth day in stage III.

Conclusion
Birth asphyxia is the most common and important cause of preventable cerebral injury occurring in the neonatal period. Serum calcium and magnesium level plays exceptionally imperative role for escaping HIE and other induced complications.

How to cite this article
Bhimte B, Vamne A. Metabolic Derangement in Birth Asphyxia due to Cellular Injury with Reference to Mineral Metabolism in Different Stages of Hypoxic-ischemic Encephalopathy in Central India. Indian J Med Biochem 2017;21(2):86-90.
Prediabetes and Undiagnosed Diabetes Mellitus: The Hidden Danger
Authors: Nanda Rachita , Abraham Jessy , Sahoo Sibasish , Ganguly Anirban , Mohapatra Eli , Patel Suprava 
Published: November 2017

ABSTRACT

Introduction
Diabetes is considered as a major challenge to the public health system in India. Recent articles clearly mention that the hidden danger in the form of prediabetes and undiagnosed diabetes is greatly adding to the burden silently. Awareness regarding the same, particularly among youth, can help diagnose the condition very early and thus, initiate early management.

Objectives
With an aim to estimate the frequency of prediabetes and undiagnosed diabetes in the adult population, a camp was organized in our institute to screen the adults in our locality by estimating fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c).

Materials and methods
A total of 246 individuals were selected for analysis after excluding the known diabetic cases. Height, weight, pulse, blood pressure (BP), waist circumference, and body mass index (BMI) were measured. Plasma fasting sugar and fasting serum lipid profile were analyzed. The HbA1c was estimated in hyperglycemic subjects.

Results
The frequency of hyperglycemia in the study population was found to be 28%. The total frequency of prediabetes was 18.3% and that of undiagnosed diabetes was 9.75%. The raised sugar could be significantly associated with age, waist circumference, BMI, hypertriglyceridemia, and cholesterol-to-high-density lipoprotein (Chol:HDL) ratio. Aging, greater BMI, hypertriglyceridemia, and raised low-density lipoprotein (LDL) depicted significant odds ratio (OR) to predict the risk factor for diabetes.

Conclusion
The hidden burden of diabetes in our locality is quite high, which, if not taken care, would result in a public health catastrophe.

How to cite this article
Patel S, Nanda R, Abraham J, Sahoo S, Ganguly A, Mohapatra E. Prediabetes and Undiagnosed Diabetes Mellitus: The Hidden Danger. Indian J Med Biochem 2017;21(2):91-95.
Comparison of Different estimated Formulas with Direct Estimation of Low-density Lipoprotein Cholesterol
Authors: Kanani Dhara N , Mishra Avanish 
Published: November 2017

ABSTRACT

Introduction
Recent recommendations of the Adult Treatment Panel and the Adolescents Treatment Panel of the National Cholesterol Education Program make the low-density lipoprotein cholesterol (LDL-C) levels in serum the basis of classification and management of hypercholesterolemia. This makes accurate reporting of LDL-C decisive in the management of coronary heart disease (CHD). Direct measurement of LDL by homogeneous method is accurate but reagent is costly. Therefore, we have to compare different calculated LDL values with direct LDL (D-LDL) values.

Aim
The aim of this study was (1) to decide if LDL-C level was underestimated/overestimated after it was calculated using the formulae compared with direct measurement of LDL-C and (2) to choose the best calculated method that compares maximum with the direct method.

Materials and methods
We measured total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL), D-LDL by direct homogeneous method in 500 fasting samples. Simultaneously, Friedewald's (F-LDL-C), modified Friedewald's (MF-LDL-C), and Anandaraja's (A-LDL-C) formulas were also used for calculation of LDL-C.

Results
A good correlation was found between D-LDL-C as compared with F-LDL-C, MF-LDL-C, and A-LDL-C. Pearson's coefficient of correlation between MF-LDL-C and D-LDL-C was 0.94, which was moderately higher than other calculated methods. Pearson's coefficient of correlation between A-LDL-C and D-LDL-C was 0.92 and F-LDL-C and D-LDL was 0.93.

Conclusion
In conclusion, among the three LDL-C formulas, the Friedewald formula and Anandaraja' s formulas give a higher percentage of error compared with the modified Friedewald formula Therefore, modified Friedewald's formula is better than the other two formulae for calculating LDL-C in a more cost-effective manner and can be used in large population studies.

How to cite this article
Kanani DN, Mishra A. Comparison of Different Estimated Formulas with Direct Estimation of Low-density Lipoprotein Cholesterol. Indian J Med Biochem 2017;21(2):151-156.
Effect of Sucralose on Glucose Uptake in Rat L6 Myotubes
Authors: Prakash Shubha N , Shanthakumari Jayakumari , Devanath Anitha 
Published: November 2017

ABSTRACT

Introduction
With growing awareness of the link between diet and health and the problem of obesity, public concern over sugar levels in the diet is forcing a worldwide trend toward cutting down on sugar by using artificial sweeteners (AS).

Aim
To study the effect of increasing concentrations of sucralose (an AS) on glucose uptake in rat L6 myotubes.

Materials and methods
The L6 cell line from American type cell culture (ATCC) was grown in Dulbecco's Modified Eagle's Medium (DMEM) and differentiated into myotubes. The wells were exposed to either 0, 1 nM, 1 μM, or 1 mM of sucralose alone or with 10 nM insulin for 24 hours. Glucose uptake was studied after this period.

Results
Significant decrease was seen between the insulin-stimulated basal glucose uptake and insulin-stimulated glucose uptake across all the concentrations of sucralose treatment.

Conclusion
Increased concentration of sucralose appears to decrease glucose uptake even on insulin stimulation.

Clinical significance
It may not be beneficial to use sucralose in certain groups of people who have insulin resistance or are prone to it.

How to cite this article
Prakash SN, Shanthakumari J, Devanath A. Effect of Sucralose on Glucose Uptake in Rat L6 Myotubes. Indian J Med Biochem 2017;21(2):162-165.
Quality assessment of integrated water vapour measurements at the St. Petersburg site, Russia: FTIR vs. MW and GPS techniques
Authors: Virolainen Yana A. , Timofeyev Yury M. , Kostsov Vladimir S. , Ionov Dmitry V. , Kalinnikov Vladislav V. , Makarova Maria V. , Poberovsky Anatoly V. , Zaitsev Nikita A. , Imhasin Hamud H. , Polyakov Alexander V. , Schneider Matthias , Hase Frank , Barthlott Sabine , Blumenstock Thomas 
Published: November 2017

Abstract. The cross-comparison of different techniques for atmospheric integrated water vapour (IWV) measurements is the essential part of their quality assessment protocol. We inter-compare the synchronised data sets of IWV values measured by the Bruker 125 HR Fourier-transform infrared spectrometer (FTIR), RPG-HATPRO microwave radiometer (MW), and Novatel ProPak-V3 global navigation satellite system receiver (GPS) at the St. Petersburg site between August 2014 and October 2016. As the result of accurate spatial and temporal matching of different IWV measurements, all three techniques agree well with each other except for small IWV values. We show that GPS and MW data quality depends on the atmospheric conditions; in dry atmosphere (IWV smaller than 6 mm), these techniques are less reliable at the St. Petersburg site than the FTIR method. We evaluate the upper bound of statistical measurement errors for clear-sky conditions as 0.29 ± 0.02 mm (1.6 ± 0.3 %), 0.55 ± 0.02 mm (4.7 ± 0.4 %), and 0.76 ± 0.04 mm (6.3 ± 0.8 %) for FTIR, GPS, and MW methods, respectively. We propose the use of FTIR as a reference method under clear-sky conditions since it is reliable on all scales of IWV variability.
A Nietzschean Critique of Metaphysical Philosophy
Authors: Mitchell Jonathan 
Published: November 2017

Abstract
This article provides a new account of Nietzsche's critique of metaphysical philosophy. After framing Nietzsche's anti-metaphysical project (section 1), I suggest that to understand the logic of his critique we should reconstruct a taxonomy that distinguishes between “rich metaphysics” and “thin metaphysics” (section 2). I then consider Nietzsche's methodological critique of “rich metaphysics,” arguing that his position, which alleges motivational bias against “rich metaphysics,” is not compelling, since even granting that previous “rich metaphysicians” exemplified such bias there is no reason that a new “rich metaphysician” should necessarily do so (section 3). Nonetheless, there is much of interest in the second aspect of Nietzsche's critique, understood in terms of indifference to “thin metaphysics,” which I consider in section 4. I argue that the existing readings are unsatisfactory, and as an alternative we should think of this idea in skeptical terms by drawing on an argument from “thin metaphysical” disagreement.
The Local Polish Community in Action: The Polish Studies Program at Central Connecticut State University
Authors: Vickrey Renata C. 
Published: November 2017

Abstract
Connecticut welcomed a considerable number of Polish immigrants in the late nineteenth century, and again just after World War II. The latter group included a large number of intellectuals, politicians, and artists. They actively joined civic organizations like the Polish American Congress (PAC). The 1960s and 1970s was a dynamic time for the Connecticut Division of the PAC especially the Committee on Education and Culture. Their work was instrumental in getting the state to establish a Polish Studies Program at Central Connecticut State College. The program allowed for in-depth academic courses related to Poland’s history, politics, and culture, and the establishment of a Polish Heritage Room and Collection in the university library. The Program also had a community-outreach function that provided evening lectures and cultural events free to the public. Later, various endowments allowed several cultural programs to be sustained and an endowed chair in Polish Studies to be created. Today the program is on a firm footing. A formal minor in Polish History is now available and community programs have expanded to include public lectures delivered by prominent historians, writers, musicians, journalists, politicians, and film makers draw large audiences. This article presents a case study in how local community groups working with university officials and elected state and local government representatives can successfully create a high quality Polish Studies program that benefits both the university community and the larger surrounding population.
Alternative Performance Measures and ESMA Guidelines: Improving Stakeholders’ Communication
Authors: Magli Francesca , Nobolo Alberto , Ogliari Matteo 
Published: November 2017

In a world more interconnected and globalized, the Entities periodically communicate to stakeholders, and in general to market, their performances and results. The Entities use, in their financial communication, Alternative Performance Indicators (APM) that are not required by accounting principles. APM are increasingly used by Entities to help provide insights on performance. These indicators are a financial measure of historical or future financial performance, financial position, or cash flows, other than a financial measure defined or specified in the applicable financial reporting framework. This study aims to analyse the spread of APM, investigating the financial communications of Listed Italian Industrial Entities on FTSE-MIB index 40. As APM have become more widespread, their reporting has turned out to be an hot topic around the world for prepares, stakeholders, auditors and regulators. The European Securities and Markets Authority issued new guidelines that aim to improve the usefulness and transparency of Alternative Performance Measures. In the second part, the study aims to analyse how the Entities expects to apply these new guidelines and the impacts on financial communication.
Entre el mito y la historia: el Éxodo de los israelitas desde Egipto a Canaán.
Authors: Villar Vegas David 
Published: November 2017

El presente ensayo parte de la premisa temática de que para realizar una adecuada exposición sobre el Éxodo de los israelitas desde Egipto a Canaán es imprescindible contar con las aportaciones de los hallazgos arqueológicos y de las fuentes literarias, tanto de la Biblia como fuera de ella, y con el mayor número de investigaciones que los especialistas de esta materia hayan realizado.Se utiliza como perspectiva teórico-metodológica un enfoque crítico que lleva a presentar, en primer lugar, lo aportado por cada una de las fuentes y lo sostenido por los diversos enfoques, para después realizar una contrastación de todo ello con el objetivo de que lo sostenido en cada uno de los temas analizados tenga un fuerte apoyo teórico y empírico.
This essay focuses on the thematic premise which realizes a suitable exhibition of the Israelite´s Exodus from Egypt. It is essential to rely on the contributions of the archaeological findings, the literary sources and the majority of the Bible with the most number of research studies conducted by the specialists of this matter.There is a theoretical - methodological perspective and a critical approach that leads to presenting, first, the contribution for each of the sources and the support for the diverse approaches. Later, it will focus on a contrast of all of this with the aim that the support for each of the analyzed topics has a strong theoretical and empirical support.