bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant analysis of protein from fresh and dry leaf of Orthosiphon aristatus (Blume) Miq.
Authors: Ramachandran Heeravathy , Rahmat Zaidah 
Published: September 2024

Orthosiphon aristatus (Blume) Miq. is a folklore plant consumed as brewed tea for various health benefits. The white variety of the plants leaf and stem are predominantly sold in the market in dried form, blooming as a natural herbal product. To date, no proteomics and antioxidant studies are available on the fresh and dried leaf protein extract of O. aristatus since most studies take an interest in the crude extracts of plants. Thereupon, this study focuses on the One-dimensional (1D) electrophoretic pattern of the fresh and dry leaf determined via sodium dodecyl-sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Additionally, antioxidant proteins are currently being focused on for their link to controlling disease through their potential to destroy free radicals that are present in excess. Hence, an antioxidant assay was conducted for the fresh and dry leaf protein extract using 2,2-Diphenyl-1-picrylhydrazyl (DPPH) free radical assay and ferric reducing antioxidant power (FRAP) assay. The electrophoretic pattern obtained resulted in approximately 16 and 10 bands for the fresh and dry leaves respectively. As for the antioxidant activity, the dry leaf had higher radical scavenging activity and higher reducing power compared to the fresh leaf. The findings obtained provides insight in to the protein content and antioxidant activity found in the protein extract of fresh and dry leaves of O. aristatus. Hence, further detailed study of the protein extracts could further unveil their therapeutic potential.
Investigating performance of optical communication system with FSO/OWC channel
Authors: Shafi Faizan , Hannan Mohammad , Nakkeeran Rangaswamy 
Published: September 2024

AbstractIn recent years, the evolution of optical wireless communication (OWC) system has emerged as a viable alternative to radio frequency communication. These technologies provide an effective solution for addressing the need for point-to-point communication, offering benefits such as higher bandwidth, faster data rates, no licensing requirements, low power usage, quick and simple installation, enhanced security, and resistance to electromagnetic interference. In this article, we analyze two wireless optical communication systems: one using an FSO channel and the other using an OWC channel. The analysis focuses on range and quality factor as performance metrics. We examine the performance of one-to-many Tx/Rx FSO/OWC channel under three different atmospheric conditions: clear weather, haze, and fog, using eye diagrams. The system analysis includes mathematical models for the received optical power and the pointing error. Additionally, we investigate the impact of spatial diversity on the performance of FSO/OWC channel with configurations of 1 × 1, 2 × 2, 4 × 4, and 8 × 8. Our findings indicate that the 8 × 8 FSO/OWC configurations yield better results compared to other configurations and the OWC channel performs well over long distances up to 110 km, while the FSO channel is more suitable for short range communication up to 37 km.
A quick parameter configuration tool for SCHISM’s ocean transport simulation of radioactive materials
Authors: Yang Zi-Yi , Huang Pei-Chieh , Chiang Yu 
Published: September 2024

Abstract
A quick tool capable of processing output files generated by the SCHISM particle tracking module has been developed to handle complex data processing procedures and conduct parameter sensitivity testing. This tool performs calculations, considering the influence of half-lives and partition coefficients, for the conversion of activity concentrations, plots particle diffusion trajectories, conducts statistical analyses of regional particle amounts, and presents activity concentration within the defined area. Using the IAEA MODARIA program as an example, this study investigates the transport of radioactive 137Cs in the ocean following the Fukushima accident on March 11, 2011. A three-year diffusion simulation was conducted by incorporating data such as ocean currents, wind fields, and tides. The calculated results demonstrate a high level of consistency with measurements, and the calculated results in the low activity concentration fall within the variability range reported in the literature.
What a nominal predicate may mean: eel, merfolk, and other creatures
Authors: Oshima David Y. 
Published: September 2024

Abstract
A nominal predicate construction (NPC; e.g. “Cicero is {Tully/an orator}”) typically indicates the relation of identity or inclusion. NPCs, however, may receive marked interpretations as well, as in “I’m the ham sandwich” and “Their car is a peculiar color”; the former does not entail that the speaker is identical to the sandwich, and the latter does not entail that the car belongs to a set of colors. This article identifies, classifies, and analyzes such marked NPCs in English and Japanese, thereby enriching the taxonomy of NPCs acknowledged in the existing literature. It will be argued that both Japanese and English NPCs may indicate either (i) one of a handful of relatively specific semantic relations including the one of identity/inclusion, or (ii) an unspecified relation that is to be contextually inferred. The English NPC is semantically less flexible than the Japanese one, being compatible with a narrower range of specific semantic relations and allowing the unspecified-relation interpretation less leniently. The English NPC, on the other hand, is more liberally used in comparison to its counterparts in some related languages (e.g. German). The analysis put forth makes a good vantage point for general-linguistic and typological inquiries as to how languages in general may contrast with each other in terms of what types of situations can be described with a NPC.
The crystal structure of ethyl 2-amino-4-(cyanophenyl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carboxylate, C19H18N2O4
Authors: Li Zhang , Hai-Yan Yu 
Published: September 2024

Abstract
C19H18N2O4, triclinic, P21/n (no. 14), a = 11.930(6) Å, b = 7.638(4) Å, c = 18.370(4) Å, β = 97.959(9)°, V = 1657.9(13) Å3, Z = 4, R

gt
(F) = 0.0497, wRref
(F
2) = 0.1437, T = 296(2) K.
Crystal structure of (3-(dimethoxymethyl)-5-methoxy-1H-indol-1-yl)(5-fluoro-2-iodophenyl)methanone, C19H17FINO4
Authors: Yuan Jia-Cheng , Zhang Yue , Zhou Yan , Tang Chen-Chen , Cong Wei 
Published: September 2024

Abstract
C19H17FINO4, triclinic, P1̄ (no. 2), a = 7.1158(2) Å, b = 11.1914(3) Å, c = 12.4974(3) Å, α = 73.015(2)°, β = 87.945(2)°, γ = 78.137(2)°, V = 931.19(4) Å3, Z = 2, R

gt
(F) = 0.0563, wRref
(F
2) = 0.1639, T = 293(2) K.
Crystal structure of 2-(2,3-bis(4-methoxyphenyl)-1H-pyrrolo[2,3-b]quinoxalin-1-yl)anilin, C30H24N4O2
Authors: Tian Hangzhou , Chen Geyu , Ma Jiejie , Tong Hongjuan , Liu Bin 
Published: September 2024

Abstract
C30H24N4O2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 8.7813(5) Å, b = 12.2074(7) Å, c = 12.7561(7) Å, α = 112.071(2)°, β = 106.856(2)°, γ = 92.265(2)°, V = 1,195.65(12) Å3, Z = 2, R
gt(F) = 0.0586, wR
ref(F
2) = 0.1534, T = 170 K.
Numerical analysis and experimental research on the vibration performance of concrete vibration table in PC components
Authors: Zou DeFang , He ZiHan , Cheng XueFei , Yu WenDa 
Published: September 2024

Abstract
Vibration table is the key equipment to realize high efficiency and high quality forming and compacting of concrete in prefabricated component (PC) production line, and its performance directly affects the shape quality and compressive strength of PC components. However, the operating parameters of the vibration table are difficult to match the rheology of the concrete during the construction process, which directly leads to a low molding efficiency or unqualified shape quality in the case of slab-type components. Therefore, it is crucial to accurately describe the concrete flow behavior during vibration to improve the construction performance and compaction effect. In this work, the coupled theory of computational fluid dynamics and discrete element is used to study the concrete vibration and compacting characteristics, and the influence of process parameters on vibration performance is analyzed in order to realize the adjustment and optimization of key parameters. First, the concrete solid-liquid two-phase model parameters are calibrated by V-shaped funnel experiments and slump experiments. Then, based on the simulation results, the homogeneity and compactness of concrete are discussed using the segmented sieving method and the slicing method, and the indexes for evaluating the working performance of the vibration table are proposed. Finally, the relationship between vibration frequency (20–30 Hz), vibration amplitude (3–4 mm), and vibration time (15–35 s) and concrete vibration compaction characteristics is investigated to provide a theoretical basis for improving the molding efficiency and mold quality of PC components.
Immune checkpoint inhibitor induced hypophysitis: a specific disease of corticotrophs?
Authors: Patel Nishchil , Hirwa Kagabo , Gardner Gemma , Pearce Kirsten , Jeffery Jinny , Iqbal Fizzah , Flanagan Daniel 
Published: September 2024

Introduction
The aim of this study was to define functional and anatomical pituitary disease at the time of presentation following immune checkpoint inhibitor (ICI) therapy and to describe any changes in pituitary function over time.

Methods
We conducted a retrospective observational audit of patients on ICI therapy at our centre between January 2013 and September 2023. We reviewed all patients on ICI therapy under the care of the oncology department at University Hospital Plymouth, a 1000-bedded hospital serving a population of 500,000 people. From this group, we identified all individuals referred to the endocrinology department with a suspected diagnosis of adrenal insufficiency. Patients were established on adrenal steroid replacement and subsequently underwent formal pituitary testing. People were included if they had pituitary disease, as evidenced by low ACTH, other pituitary dysfunction and/or abnormalities on pituitary imaging.

Results
Nine hundred and fifty-four patients received ICI therapy during the study period, and 37 (a prevalence of 3.9%) developed hypothalamic–pituitary–adrenal axis dysfunction. Their mean age was 65 years, and 70% were male. About 86.5% of the total patients affected were treated for metastatic malignancies. Ten of the 37 patients died during follow-up as a direct consequence or complication of their primary cancer diagnosis. The median interval for the onset of symptoms was 4 months. Following repeated testing, there was no recovery in cortisol or ACTH levels for any individual. Other permanent anterior pituitary hormone defects were unusual. Hypophysitis associated with immunotherapy appears to specifically target the corticotrophs, with no evidence of recovery over time. There was a specific abnormality seen in MRI scans of 7 of 27 patients who had scans, which appeared to be a particular feature of immune-mediated hypophysitis. These were confined to the anterior aspect of the pituitary gland, appearing as striations, and were not visible on any of the scans performed more than 3 months after the likely onset of the disease.

Conclusion
These data show that immune-related hypophysitis is a common complication of immune checkpoint inhibitor therapy. This may result in an imaging abnormality within the areas of the pituitary that are richest in corticotrophs. The endocrine consequence of this is a permanent defect in ACTH and, therefore, cortisol production.
Typical morphological characteristics of the immunohistochemical subtypes of pituitary microadenomas: a dual center study
Authors: Zhang Li , Yan Shuai , Xie Shen-ke , Wei Yi-tong , Liu Hua-peng , Li Yin , Wu Hai-bo , Wang Hai-liang , Xu Peng-fei 
Published: September 2024

Purpose
This study aimed to investigate the relationship between magnetic resonance image (MRI) features and the immunohistochemical subtypes of pituitary microadenomas (PMAs) characterized by location and growth pattern.

Materials and methods
A double-center, retrospective review of MRI characteristics was conducted in 57 PMA cases recorded from February 2014 to September 2023, identified based on the 2017 World Health Organization classification of pituitary gland tumors. The geometric center of the tumor was defined, and the possibility of PMA vertical or lateral growth patterns was evaluated according to the ratio of maximum diameter between the X and Y axes.

Results
Among the PMAs, somatotroph adenomas (STAs) significantly frequented the lateral-anteroinferior portion of the pituitary gland (P = 0.036). Lactotroph adenomas (LTAs) showed a significant locational preference for the lateral-posteroinferior portion (P = 0.037), and gonadotroph adenomas (GTAs) were predominantly located in the central-anteroinferior portion (P = 0.022). Furthermore, PMAs in the suprasellar portion exhibited vertical extension with statistical significance (P = 0.0).

Conclusion
In our cohort, micro-STAs were predominantly located in the lateral-anteroinferior portion of the pituitary gland, micro-LTAs in the lateral-posteroinferior portion, and micro-GTAs in the central-anteroinferior portion. The growth pattern of PMAs was highly correlated with their vertical position instead of their immunohistochemical subtypes. Therefore, MRI shows potential in differentiating partial PMA subgroups, especially cases within the silent groups.
HARMONIZING EURASIAN DEVELOPMENT THROUGH THE IMPLEMENTATION AND MODERNIZATION OF THE BELT AND ROAD INITIATIVE
Authors: Сунь Ч. 
Published: September 2024

В статье рассмотрен выбор постсоветскими странами Евразии моделей развития по пути модернизационных реформ. Показано, что в этих моделях сочетаются формальная «вестернизация» в политичес­кой сфере и «содержательная национализация». Проанализированы труд­ности модернизации в процессе построения национальных государств (несовместимость религиозных и культурных традиций со светскими политическими системами, риски, возникающие при внедрении сверх­сильной президентской власти, риски политического плюрализма, проб­лемы реструктуризации систем социального управления и т.д.). Пока­зано, что модернизация - это не просто готовая западная модель с ак­центом на экономическом росте, она также должна быть направлена на социальное развитие и достижение общественной справедливости. Рассмотрены выстраивание стратегической инициативы «Один пояс - один путь» и ее влияние на развитие постсоветских стран Евразийского макрорегиона (в том числе на основе совершенствования систем управ­ления и совместного поиска новых возможностей для их развития).
The article examines the development models chosen by post-Soviet Eura­sian countries as they pursue modernization reforms. It highlights how they blend formal “westernization" in the political sphere with “substantive natio­nalization." Here we analyze the challenges of modernization in nation-buil­ding (including the incompatibility of religious and cultural traditions with secular political systems, risks from the introduction of super-powerful pre­sidential authority, risks of political pluralism, issues in restructuring social governance systems, etc.). It is shown that modernization should not be seen merely as adopting a Western model focused on economic growth but should also aim for social development and social justice. The article also examines the construction of the strategic Belt and Road Initiative and its impact on the development of post-Soviet countries in the Eurasian macro-region, particularly through improving governance systems and jointly seeking new opportunities for development.
ASSESSMENT OF CLIMATE RISKS TO RURAL LIFE IN THE EUROPEAN NORTH (Case Study of Primorsky District, Arkhangelsk Oblast)
Authors: Ненашева М.В. 
Published: September 2024

В статье на материалах социологического исследования, проведен­ного летом 2022 г. в Приморском районе Архангельской области, рас­сматривается влияние изменения климата на жизнедеятельность сель­ского населения Европейского Севера. Представлены данные по изме­нению климата на территории Приморского района. Показано, что на фоне потепления меняется динамика опасных гидрометеорологических явлений, которые оказывают воздействие на экономику и социум. В ре­зультате глубинных интервью с сельскими жителями Приморского района выяснилось, что наибольшую угрозу для их жизнедеятельности представляют сильный (штормовой) ветер, туман, оттепель, наводне­ния, изменение сроков ледостава и ледохода. Перечисленные опасные природно-климатические явления и процессы оказывают негативное влияние на судоходство, рыболовство, продовольственную и медицин­скую безопасность местных жителей, а также на состояние инфра­структуры поселков. Проведена оценка уязвимости местного населения и его способности к адаптации к изменению климата. Обнаружено, что жители деревень не воспринимают изменение климата как главную угрозу их жизнедеятельности, а рассматривают его сквозь призму более важных и насущных социально-экономических проблем. Адаптация сель­ского населения к изменениям климата носит реактивный характер и основана на применении традиционных знаний и умений в процессе жизнедеятельности. Результаты исследования могут быть использо­ваны для разработки региональных стратегий и мероприятий по адап­тации северных сообществ к изменению климата.
This article investigates the impact of climate change on the livelihoods of the rural population in the European North, specifically based on a socio­logical study conducted in the summer of 2022 in the Primorsky District of Arkhangelsk Oblast. The paper presents data on climate change in the Primorsky District, showing that warming trends are altering the dyna­mics of dangerous hydrometeorological phenomena that affect the economy and society. In-depth interviews with rural residents revealed that the greatest threats to their livelihoods are strong (storm) winds, fog, thaws, floods, and changes in the timing of ice formation and ice drift. These hazardous natural and climatic phenomena negatively impact navigation, fishing, food and medical safety, and local infrastructure. The study assessed the vulnerability and adaptability of the local population to climate change. It found that villagers do not perceive climate change as the main threat to their livelihoods but view it through the lens of more pressing social and economic issues. Their adaptation to climate change is reactive, relying on traditional knowledge and skills. The results of this study can be used to develop regional strate­gies and measures for the adaptation of northern communities to climate change.
PARTICIPATORY BUDGETING IN EXERCISING THE POWERS OF PUBLIC AUTHORITIES ACROSS RUSSIAN FEDERATION CONSTITUENT ENTITIES
Authors: Петрова И.В. , Шатохин Д.А. , Паксиваткина В.А. 
Published: September 2024

Реализация проектов инициативного бюджетирования в Российской Федерации на местном уровне за время начиная с 2007 г. дала видимые результаты в отношении эффективности осуществления полномочий органов местного самоуправления. На местах сформировались деятель­ные локальные сообщества, являющиеся субъектами генерации и реали­зации управленческих решений органов местного самоуправления. С уче­том положительного внедрения элементов инициативного бюджети­рования в методологию муниципального управления становится возмож­ным говорить о целесообразности масштабирования процедур инициа­тивного бюджетирования на региональный уровень управления, их при­менения в деятельности органов государственной власти субъекта Рос­сийской Федерации. В этом случае встает задача определения того, в ка­ких сферах и каким образом механизмы инициативного бюджетирования могут быть встроены в деятельность региональных органов власти. В данной статье описываются предпосылки к распространению ме­ханизмов инициативного бюджетирования на полномочия органов госу­дарственной власти, рассматриваются процедуры инициативного бюд­жетирования в управленческом процессе регионального уровня. Мате­риал исследования может быть использован при разработке подходов к согласованию отраслевых стратегических и программных документов, при составлении программных документов развития инициативного бюджетирования в субъектах Российской Федерации.
The implementation of participatory budgeting projects at the local level in the Russian Federation since 2007 has yielded visible results in effectively exercising the powers of local self-government bodies. Active local commu­nities have emerged, becoming key players in generating and implementing management decisions by local authorities. Given the successful integration of participatory budgeting elements into municipal management, it is now feasible to consider scaling these procedures to the regional level of gover­nance, integrating them into the activities of public authorities of the Russian Federation’s constituent entities. This raises the task of identifying the areas and methods for incorporating participatory budgeting mechanisms into re­gional authorities’ activities. This article describes the prerequisites for extending participatory bud­geting mechanisms to the powers of public authorities and examines the pro­cedures of participatory budgeting in regional management processes. The research findings can be used in developing approaches to coordinate sectoral strategic and program documents and prepare program documents for advancing participatory budgeting in the constituent entities of the Russian Federation.
Prayer as Transgression?: The Social Relations of Prayer in Healthcare Settings by Sonya Sharma and Sheryl Reimer-Kirkham, Rachel Brown and Melania Calestani
Authors: Mashadi Samar 
Published: September 2024

Prayer as Transgression?: The Social Relations of Prayer in Healthcare Settings by Sonya Sharma and Sheryl Reimer-Kirkham, Rachel Brown and Melania Calestani. McGill-Queen’s University Press, 2020. 240pp., 9 photos, 1 table. Pb. CDN$125. ISBN-13: 9780228001645; Hb. CDN$$40.95. ISBN-13: 9780228001652.
The arm of a large-scale bronze statue from Aigion, Achaea, Greece
Authors: Vordos Andreas G. 
Published: September 2024

The arm of the large-scale bronze statue presented in the current research was handed over in 1951 to the Ephorate of Antiquities in Aigio of Achaia and constitutes a typical yet exquisite example of Peloponnesian oversized statuary in bronze. The area where the arm was found coincides with the location of the ancient agora, as well as, according to previous excavation works, the place where the temenos of Zeus Soter, patron deity of the ancient polis of Aigion, is located. Based on the surviving fragment/limb, several issues regarding statue typology are further discussed, while its posture is suggested as ‘standing in grandeur’.
The identification of a divine figure, probably that of Zeus, is supported by the location of discovery and the object it was supposedly holding, combined with the numismatic issues of Aigion depicting the same type of statuary of the supreme god. The dating of the statue in mid Hellenistic years onwards agrees with the scientific analysis of the alloy, carried out in the laboratories of the National Archaeological Museum in Athens.