bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantifying rates of cell migration and cell proliferation in co-culture barrier assays reveals how skin and melanoma cells interact during melanoma spreading and invasion
Authors: Haridas Parvathi , Penington Catherine J. , McGovern Jacqui A. , McElwain D. L. Sean , Simpson Matthew J. 
Published: April 2017

ABSTRACTMalignant spreading involves the migration of cancer cells amongst other native cell types. For example,in vivomelanoma invasion involves individual melanoma cells migrating through native skin, which is composed of several distinct subpopulations of cells. Here, we aim to quantify how interactions between melanoma and fibroblast cells affect the collective spreading of a heterogeneous population of these cellsin vitro. We perform a suite of circular barrier assays that includes: (i) monoculture assays with fibroblast cells; (ii) monoculture assays with SK-MEL-28 melanoma cells; and (iii) a series of co-culture assays initiated with three different ratios of SK-MEL-28 melanoma cells and fibroblast cells. Using immunostaining, detailed cell density histograms are constructed to illustrate how the two subpopulations of cells are spatially arranged within the spreading heterogeneous population. Calibrating the solution of a continuum partial differential equation to the experimental results from the monoculture assays allows us to estimate the cell diffusivity and the cell proliferation rate for the melanoma and the fibroblast cells, separately. Using the parameter estimates from the monoculture assays, we then make a prediction of the spatial spreading in the co-culture assays. Results show that the parameter estimates obtained from the monoculture assays lead to a reasonably accurate prediction of the spatial arrangement of the two subpopulations in the co-culture assays. Overall, the spatial pattern of spreading of the melanoma cells and the fibroblast cells is very similar in monoculture and co-culture conditions. Therefore, we find no clear evidence of any interactions other than cell-to-cell contact and crowding effects.
Religious struggles after Typhoon Haiyan: a case study from Bantayan Island
Authors: O’Connell Erin P. , Abbott Roger P. , White Robert S. 
Published: April 2017

PurposeThe purpose of this paper is to examine religious struggles and loss of faith in Christian survivors of Typhoon Haiyan in the Philippines and explore whether any demographic characteristics or experiences during the disaster may have contributed to these responses.Design/methodology/approachA quantitative survey was used to assess a variety of concepts related to religious responses after disaster. Data were collected using a mix of non-random, convenience sampling methods, with a total sample of 1,929 responses.FindingsReligious struggles, anger toward God, and apostasy after the typhoon was generally low, although a significant minority of respondents expressed feelings of confusion about God and wondered whether God cared about them. Factors that influenced the experience of religious struggles included: education level, socio-economic status, denomination, barangay, loss of loved ones in the disaster, format of post-disaster church fellowship meetings, and the importance of God in their lives prior to the disaster.Practical implicationsHaving an appropriate and supportive faith-based environment for those of faith to work through religious struggles is important for supporting emotional and psychological recovery after disaster.Originality/valueThis study explores how disasters can impact individuals’ beliefs and their relationship with God in a non-Western context. This information enhances our understanding on how humanitarian and faith-based organizations can help support emotional and psychological recovery among impacted populations, particularly those who experience struggles.
An integrative approach to understand vulnerability and resilience post-disaster
Authors: Rey Tony , Le De Loic , Leone Frederic , Gilbert David 
Published: April 2017

Purpose
The purpose of this paper is to develop a multidimensional approach for effectively managing natural disasters; this paper has three research objectives. First, it provides an analysis on the hydro-geomorphological effects of the cyclone in the urban context. Second, it proposes an analysis for the vulnerability and resilience recovery of the populations living in urban areas. Third, it specifies the implications for sustainable recovery and longer-term disaster risk reduction.

Design/methodology/approach
A detailed case study of the tropical cyclone Pam was carried out to identify hydro-geomorphologic effects and damages in an urban area and specific problems associated with managing natural disaster in Vanuatu.

Findings
The investigations reveal that living in an urban area increases a population’s exposure to hydrological, weather and sea-related risks. Whereas advice on cyclones seems to work very well, the coastal risks and floods seem to be underestimated with a very high exposure and vulnerability to risk. Pre-existing vulnerabilities were exacerbated after cyclone Pam. However, other communities have been able to reinforce their resilience through local initiatives. The government and outside aid were very quick to react, despite problems of coordination, exchange of information, communication and long-term strategy.

Practical implications
The bottom-up, top-down, local and global approaches, applied on the time scales, should lead to actions that will reinforce the ability of the people of Vanuatu to adapt to high-energy events and to the effects of climate change.

Originality/value
This paper highlights the importance of understanding how the urban communities are vulnerable to natural hazards and of strategies for increasing their resilience.
Forensic investigation of the 2011 Great East Japan Earthquake and Tsunami disaster
Authors: Nakasu Tadashi , Ono Yuichi , Pothisiri Wiraporn 
Published: April 2017

Purpose
Using the forensic investigation (FORIN) approach, the purpose of this paper is to identify the factors that exacerbated the loss of human life in one of the most devastated local municipalities on the coast by 2011 Great East Japan Earthquake and Tsunami (GEJET) disaster.

Design/methodology/approach
This paper begins by reviewing the extent of damage to the local municipalities along the Sanriku ria coast, which has a long history of tsunami disasters. Second, the paper compares previous major tsunami events by using a human vulnerability index, and applies this index to detect the city of Rikuzentakata. Third, the paper identifies the root causes of the GEJET disaster in the city. Interview records with disaster victims were used to elucidate the main factors that exacerbated the number of deaths.

Findings
The study indicates that the FORIN approach can be effectively applied to identify the target city for this case study and to point to those factors the most exacerbated human sufferings, and also provides many lessons based on research findings and methodologies to support building resilient societies in the future.

Originality/value
This paper indicates FORIN approach as an effective research template by investigating the GEJET disaster.
Human resource development practices, managers and multinational enterprises in Australia
Authors: Sablok Gitika , Stanton Pauline , Bartram Timothy , Burgess John , Boyle Brendan 
Published: April 2017

Purpose
The purpose of this paper is to examine the HRD practices of multinational enterprises (MNEs) operating in Australia to understand the value that MNEs place on investment in their human capital, particularly managerial talent.

Design/methodology/approach
Drawing on a representative sample of 211 MNEs operating in Australia, this paper investigates the extent (using frequencies) and determinants (using logistic regression analysis) of training and development expenditure, management development strategies, talent management and succession planning policies.

Findings
The findings suggest that less than 20 per cent of MNEs operating in Australia are investing over 4 per cent of their annual pay bill on training and development. Furthermore, almost a quarter of firms invest less than 1 per cent in training and development. However, most MNEs invest in their managers and those with high potential through the use of management development programmes, talent management strategies and succession planning. Interestingly, in comparison to US MNEs, Australian MNEs were less likely to use management development or talent management programmes for senior management or high performing staff.

Research limitations/implications
The current study is cross-sectional and represents a snapshot of MNEs’ HRD practices at one point in time. The study measured the perceptions of the most senior HR manager and did not include the views of other organisational participants. The authors suggest the need for future research studies that incorporate longitudinal research designs and the views of different organisational actors.

Practical implications
HR managers or HRD specialists need to develop a strong understanding of the Australian institutional context, as well as demonstrate the importance/business case for an integrative approach to HRD.

Originality/value
This paper fulfils an identified need to study the HRD practices of MNEs operating in Australia, particularly focusing on the value that MNEs place on their human capital.
Optimal design of multi-layer thermal protection of variable thickness
Authors: Nenarokomov Aleksey V. , Salosina Margarita O. , Alifanov Oleg M. 
Published: April 2017

PurposeThe presented paper aims to consider algorithm for optimal design of multilayer thermal insulation.Design/methodology/approachDeveloped algorithm is based on a sequential quadratic programming method.Findings2D mathematical model of heat transfer in thermal protection was considered in frame of thermal design of spacecraft. The sensitivity functions were used to estimate the Jacobean of the object functions.Research limitations/implicationsDesign of distributed parameter systems and shape optimization may be thought of as geometrical inverse problems, in which the positions of free boundaries are determined along with the spatial variables. In such problems, the missing data (i.e. the position of boundaries) are compensated for by the presence of the so-called inverse problem additional conditions. In the case under consideration, such conditions are constrains on the temperature values at the discrete points of the system.Practical implicationsResults are presented how to apply the algorithm suggested for solving a practical problem – thickness sampling for a thermal protection system of advanced solar probe.Originality/valueThe procedure proposed in the paper to solve a design problem is based on the method of quadratic approximation of the initial problem statement as a Lagrange formulation. This has allowed to construct a rather universal algorithm applicable without modification for solving a wide range of thermal design problems.
Top ranked hospitals: does diversity inclusion matter?
Authors: Futrell Gary D. , Clemons Tiffany N. 
Published: April 2017

Purpose
The purpose of this research is to compare the mission statements of the hospitals listed on the 2014 US News & World Report’s Best Hospitals List to investigate the research question, “Are high ranking hospitals (HRH) more likely than low ranking hospitals (LRH) to address cultural diversity in strategic statements?”

Design/methodology/approach
The strategic statements of 44 HRH and 56 LRH were compared using chi-square and Fisher’s exact test.

Findings
While the data do not support the notion that HRHs are more likely than LRHs to address diversity in strategic statements, HRHs are more likely than LRHs to actually devote resources to address the issues of cultural diversity.

Research limitations/implications
The current research is limited to a sample taken from the US News & World Report Best Hospitals. This is not a definitive list, and a multitude of third-party hospital raters exist – each with its own unique metrics.

Practical implications
The results do not show a relationship between a hospital’s mission statement and its ranking in the US News List of Best Hospitals. However, the findings suggest that hospitals that maintain a dedicated diversity manager/office do tend to be higher ranked.

Originality/value
This is the first known investigation of the relationship between the inclusion of diversity in hospital mission statements and hospital rankings. The research suggests that addressing diversity in strategic statements is simply not enough and that dedicated, ground-level resources are necessary to properly impact quality care and third-party ratings.
Wikipedia editing and information literacy: a case study
Authors: Dawe Lydia , Robinson Ainslie 
Published: April 2017

Purpose
This paper aims to evaluate the success of a Wikipedia editing assessment designed to improve the information literacy skills of a cohort of first-year undergraduate health sciences students.

Design/methodology/approach
In this action research case study (known hereafter as “the project” to differentiate this action research from the students’ own research), students researched, wrote and published Wikipedia articles on Australia-centric health topics. Students were given a pre- and post-test to assess levels of self-confidence in finding, evaluating and referencing information. Student work was also analysed in terms of article length and quantity and the type of information sources used.

Findings
Tests revealed that students’ self-confidence in their information literacy skills improved overall. Analysis of student work revealed that students wrote longer articles and incorporated more references than expected. References used were of appropriate quality relevant to the article despite minimal instructions.

Originality/value
There are few studies that investigate information literacy development through Wikipedia editing in Australian universities. This study shows that Wikipedia editing is an effective way to carry out student assessment prior to essay writing and an innovative platform to improve information literacy skills in undergraduate students.
The influence of contextual support on persistent sharing willingness of QQ group members
Authors: Yuan Liuliang , Liu Wei 
Published: April 2017

Purpose
The purpose of this paper is to explore the ways to encourage members in QQ knowledge-communication groups to persistently share knowledge in terms of contexts and autonomous motivations.

Design/methodology/approach
Based on self-determination theory, three important contextual factors of QQ knowledge-communication groups were selected as exogenous variables and three typical autonomous motivations as mediating variables to construct a knowledge-sharing model. Internet questionnaire surveys and data collection were conducted to test proposed hypotheses by means of structural equation modeling with AMOS.

Findings
Reciprocity, learning, and altruism have significant positive influence on persistent sharing willingness, and the degree to which each factor influences persistent sharing willingness differs considerably. Autonomy support, perceived usefulness, and relatedness support have no significantly direct influence on persistent sharing willingness, but they indirectly influence the persistent sharing behaviors by the mediating effect of different autonomous motivations.

Originality/value
This study contributes theoretically and practically. First, the results suggest that a particular motivation in different contexts has a different degree of autonomy. In addition, explanations are offered for the phenomenon that suggest that controlled motivations directly affect autonomous motivations. It was found that the contextual factors of competence support and relatedness support also have influence on different autonomous motivations, and hence encourage knowledge-sharing behaviors. Specific suggestions for QQ group managers and information seekers are proposed.
Assessing distance education students satisfaction with web-based services
Authors: Arif Muhammad , Ameen Kanwal , Rafiq Muhammad 
Published: April 2017

PurposeUniversities across the globe are spending an increasing amount of their budgets to offer web-based services to cater information need especially off-campus students. However, the success of web-based services depends on how well the target users are satisfied with the use of the web services. The purpose of this paper is to assess students’ satisfaction with the use of the Allama Iqbal Open University (AIOU) web-based services.Design/methodology/approachPilot tested questionnaire-based survey was administered to collect data from a sample of 388; selected through systematic sampling technique from the study’s population consisted of master level students belonged to 11 different academic departments of the Faculty of Social Science and Humanities at the AIOU from all over Pakistan.FindingsBased on 318 useful questionnaires, response rate 82 percent, the results show that majority of the students were satisfied with the use of at the AIOU web-based services except for online mailing books tracking system, library web OPAC and web radio service. However,t-test analysis shows that no difference was found in the opinion of male and female respondents in terms of their satisfaction with the use of the web services. ANOVA results indicate that there was no significant difference depicted in satisfaction with the use of the web services among the respondents enrolled in different disciplines of the faculty. Similarly, no significant difference was found among different age groups. Moreover, the respondents belonging to all five provinces; Punjab, Khyber Pakhtunkhwa, Sindh, Baluchistan, Gilgit Baltistan, and Federal Capital territory showed the same level of satisfaction with the use of the services. The results of regression analysis (R2=0.226) denote that both perceived usefulness and perceived ease of use significantly predicted, 22.6 percent, in students’ satisfaction with the use the web services.Practical implicationsThe study provides valuable recommendations which may be helpful for web administration of the university to improve AIOU web-based services.Originality/valueTo the best knowledge, this is the first study conducted to investigate the satisfaction with the use of the university web-based services in distance education’s perspective of Pakistan.
Pleasure in the use of new technologies: the case of e-book readers
Authors: Antón Carmen , Camarero Carmen , Rodríguez Javier 
Published: April 2017

Purpose
The purpose of this paper is to analyze the adoption process of e-book readers and examine how the perception concerning the advantages of this technology and its incompatibility with consumer values determine the pleasure felt and its effective use. The authors also propose that consumer involvement with information and communication technologies (ICTs) moderates these effects.

Design/methodology/approach
Hierarchical moderated regression analysis is used to test the proposed model with survey data from a sample of e-book reader owners.

Findings
Appraisal of the device’s reading features and the possibility for free downloading increases the pleasure found with its use and the extent to which it is actually used, whereas attachment to paper books decreases the emotional feeling, with some of these effects being moderated by the individual’s involvement with new ICTs. Pleasure mediates the influence of perceived advantages and attachment to the older technology on the use of the e-book reader device.

Practical implications
Two challenges to practitioners are suggested: to overcome the rejection of users who are less eager to experience pleasure and to use the e-reader, and to find the product’s objective or sensory characteristics that provide pleasure and promote long-lasting use.

Originality/value
The study extends previous studies on e-book readers by emphasizing the need to go beyond adoption intention. It analyzes effective use as a crucial measure of the true adoption of this technology and incorporates the perspective offered by the appraisal theory of emotion, which explains the key role of pleasure in this process.
A typology of collaborative research networks
Authors: Hayat Tsahi , Lyons Kelly 
Published: April 2017

Purpose
Many studies have investigated how the structure of the collaborative networks of researchers influences the nature of their work, and its outcome. Co-authorship networks (CANs) have been widely looked at as proxies that can help bring understanding to the structure of research collaborative ties. The purpose of this paper is to provide a framework for describing what influences the formation of different research collaboration patterns.

Design/methodology/approach
The authors use social network analysis (SNA) to analyze the co-authorship ego networks of the ten most central authors in 24 years of papers (703 papers and 1,118 authors) published in the Proceedings of CASCON, a computer science conference. In order to understand what lead to the formation of the different CANs the authors examined, the authors conducted semi-structured interviews with these authors.

Findings
Based on this examination, the authors propose a typology that differentiates three styles of co-authorship: matchmaking, brokerage, and teamwork. The authors also provide quantitative SNA-based measures that can help place researchers’ CAN into one of these proposed categories. Given that many different network measures can describe the collaborative network structure of researchers, the authors believe it is important to identify specific network structures that would be meaningful when studying research collaboration. The proposed typology can offer guidance in choosing the appropriate measures for studying research collaboration.

Originality/value
The results presented in this paper highlight the value of combining SNA analysis with interviews when studying CAN. Moreover, the results show how co-authorship styles can be used to understand the mechanisms leading to the formation of collaborative ties among researchers. The authors discuss several potential implications of these findings for the study of research collaborations.
Lessons from CXC for Caribbean higher education institutions
Authors: Griffith Stafford Alexander 
Published: April 2017

Purpose
The purpose of this paper is to show how higher education institutions in the Caribbean may benefit from the quality assurance measures implemented by the Caribbean Examinations Council (CXC).

Design/methodology/approach
The paper uses an outcomes model of quality assurance to analyse the measures implemented by the CXC to assure quality in its examinations. It considers how higher education institutions in the Caribbean can benefit from the approach to quality assurance used by that organization.

Findings
The paper suggests that there are several ways in which the quality assurance in higher education institutions may be improved by using an outcomes model which focuses on the centrality of the student experience by learning from the experiences of the CXC.

Research limitations/implications
The research uses a methodology of theoretical analysis, that is the selection and discussion of theoretical material and descriptive material, in a particular context, and considers their applicability for improving practice, in this case, in higher education institutions in the Caribbean. It therefore does not engage the collection and analysis of quantitative or qualitative data.

Practical implications
The paper suggests that quality assurance practices of higher education institutions in the Caribbean should take into account the lessons that may be learned from the quality assurance measures implemented by the CXC.

Originality/value
The paper calls attention to the need for higher education institutions to make the shift away from a purely institutional approach to quality assurance by adopting a more student-centred approach.