bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Peyronie's Disease-Like Symptoms in Men Presenting With Dupuytren Contractures
Authors: Shindel Alan W. , Sweet Genevieve , Thieu William , Durbin-Johnson Blythe , Rothschild Jennifer , Szabo Robert 
Published: July 2017

Abstract

Introduction
Peyronie's disease (PD) and Dupuytren contractures (DC) are often comorbid and are believed to have a similar underlying pathophysiologic mechanism.

Aim
To investigate the prevalence of PD-like symptoms (PDLS) in men with DC.

Methods
From October 2013 to December 2016, men who were seen and evaluated for DC were offered the opportunity to participate in an anonymous survey. The survey assessed several basic demographic and sexual health factors and included items from the International Index of Erectile Function and the Erection Hardness Scale. Men who reported PDLS were asked a series of questions derived from the Peyronie's Disease Questionnaire and for their opinions on theoretical treatment modalities for sexual problems and penile deformity.

Main Outcome Measure
Prevalence of PDLS in men with DC.

Results
One hundred forty men with DC were invited to participate; 85 surveys were returned (response rate = 61%). Twenty-two respondents (26%, 95% confidence interval = 17–35) reported PDLS. Approximately one fourth of all respondents had an Erection Hardness Scale score lower than 3. The most common specific PDLS concerns were penile curvature (91%), length loss (55%), narrowing (36%), and hinging (32%). In men with PDLS, 73% felt at least a little bothered by the symptoms when attempting sexual activity and 40% reported having sex less frequently because of the symptoms. Just 27% of men with PDLS had ever used a treatment for a sexual concern. In terms of treatments for penile deformities, 64% of men with PDLS expressed an interest in treatment administered in the form of an in-office procedure; 41% were potentially amenable to a surgical procedure.

Conclusion
The prevalence of PDLS in men with DC is similar to the prevalence of DC in men diagnosed with PD. A substantial number of these men have distress and would consider standard-of-care treatments for PD.
Shindel AW, Sweet G, Thieu W, et al. Prevalence of Peyronie's Disease-Like Symptoms in Men Presenting With Dupuytren Contractures. Sex Med 2017;5:e135–e141.
Current status of canine dirofilariosis in an endemic area of western Spain
Authors: Diosdado A. , Gómez P.J. , González-Miguel J. , Simón F. , Morchón R. 
Published: July 2017

AbstractSince dirofilariosis caused by Dirofilaria immitis is a vector-borne disease, its distribution depends on environmental conditions as well as demographic factors and the management of pets by humans. In the province of Salamanca (west-central Spain) the disease has been known for many years, appearing in an area with extensive irrigated crops along the Tormes river. Because recent demographic changes have occurred in this area, the present study has been carried out with the aim of monitoring the distribution and prevalence of the disease in the canine population of this area. For that purpose, 191 dogs were analysed through antigen and microfilaria tests and geo-referenced in a map. The overall prevalence was 5.8%, although the disease was only present in dogs from municipalities with irrigated crops in which the prevalence was 16.7%. These results indicate that D. immitis continues to be present in the province of Salamanca, and that it is associated with the presence of irrigation, but with a clear decrease in the prevalence. Causes of the decrease in prevalence, as well as the potential zoonotic risk, are discussed.
Rethinking China's Coercive Capacity: An Examination of PRC Domestic Security Spending, 1992–2012
Authors: Greitens Sheena Chestnut 
Published: July 2017

AbstractDiscussions of China's rising domestic security expenditure often present this spending as evidence of the Chinese Communist Party's strong coercive capacity. This article argues that a lack of theoretical clarity about domestic security has resulted in flawed conclusions about these expenditures and their implications for China's coercive capacity. Challenging the conventional wisdom, the article analyses China's domestic security spending from 1992 through 2012 and argues that it is important to consider not only the total amount that China spends but also how it spends these resources and the magnitude of the threats that this expenditure must address. It finds that China's domestic security spending is not historically unprecedented, is not expanding as a proportion of national expenditure, and is not necessarily high (or producing high coercive capacity) when compared to other countries. The article also shows that certain locations struggle more to fund their coercive capacity than others, and that these locations overlap with areas where internal security threats may be particularly acute. The challenges that the coercive apparatus must address have also grown over the same period during which domestic security spending has risen. Finally, attempts to improve the political position of China's coercive agents cannot be equated with improvements in their capacity to manage Chinese society. Cumulatively, this reassessment provides more evidence of the limitations on China's coercive capacity than of its strength.
MBD1 and MeCP2 expression in embryos and placentas from transgenic cloned goats
Authors: Jia Ruoxin , Zhang Guomin , Fan Yixuan , Zhou Zhengrong , Wan Yongjie , Zhang Yanli , Wang Ziyu , Wang Feng 
Published: July 2017

SummaryDNA methylation is an important form of epigenetic regulation in mammalian development. Methyl-CpG-binding domain protein 1 (MBD1) and methyl-CpG-binding domain protein 2 (MeCP2) are two members of the MBD subfamily of proteins that bind methylated CpG to maintain the silencing effect of DNA methylation. Given their important roles in linking DNA methylation with gene silencing, this study characterized the coordinated mRNA expression and protein localization of MBD1 and MeCP2 in embryos and placentas and aimed to analysis the effects of MBD1 and MeCP2 on transgenic cloned goats. Our result showed that MBD1 expression of transgenic cloned embryo increased significantly at the 2–4-cell and 8–16-cell stages (P < 0.05), then decreased at the morula and blastocyst stages (P < 0.05); MeCP2 expression in transgenic cloned embryo was significant decreased at the 2–4-cell stage and increased at the 8–16-cell stage (P < 0.05). Placenta morphology analysis showed that the cotyledon number of deceased transgenic cloned group (DTCG) was significantly lower than that the normal goats (NG) and in the live transgenic cloned goats (LTCG) (P < 0.05). MBD1 and MeCP2 were clearly detectable in the placental trophoblastic binucleate cells by immunohistochemical staining. Moreover, MBD1 and MeCP2 expression in DTCG was significant higher than in the NG and the LTCG (P < 0.05). In summary, aberrant expression of methylation CpG binding proteins MBD1 and MeCP2 was detected in embryonic and placental development, which reflected abnormal transcription regulation and DNA methylation involved in MBD1 and MeCP2. These findings have implications in understanding the low efficiency of transgenic cloning.
HUSSERL AND GÖDEL’S INCOMPLETENESS THEOREMS
Authors: HARTIMO MIRJA 
Published: July 2017

AbstractThe paper examines Husserl’s interactions with logicians in the 1930s in order to assess Husserl’s awareness of Gödel’s incompleteness theorems. While there is no mention about the results in Husserl’s known exchanges with Hilbert, Weyl, or Zermelo, the most likely source about them for Husserl is Felix Kaufmann (1895–1949). Husserl’s interactions with Kaufmann show that Husserl may have learned about the results from him, but not necessarily so. Ultimately Husserl’s reading marks on Friedrich Waismann’s Einführung in das mathematische Denken: die Begriffsbildung der modernen Mathematik, 1936, show that he knew about them before his death in 1938.
AUTOMATED CORRESPONDENCE ANALYSIS FOR THE BINARY EXTENSIONS OF THE LOGIC OF PARADOX
Authors: PETRUKHIN YAROSLAV , SHANGIN VASILY 
Published: July 2017

AbstractB. Kooi and A. Tamminga present a correspondence analysis for extensions of G. Priest’s logic of paradox. Each unary or binary extension is characterizable by a special operator and analyzable via a sound and complete natural deduction system. The present paper develops a sound and complete proof searching technique for the binary extensions of the logic of paradox.
Messages from Above: Conflict and Convergence of Messages to the Catholic Voter from the Catholic Church Hierarchy
Authors: Holman Mirya R. , Shockley Kristin 
Published: July 2017

Abstract
The Catholic Church often plays a policy and mobilization role in American politics. We assess the degree to which the Catholic Church hierarchy — including national and state conferences of bishops — can provide uniform information to parishioners about political participation. Using a textual analysis of information distributed to parishioners in Florida in the 2012 election, we evaluate how much political information is conveyed to parishioners, the sources of this information, and the factors associated with higher or lower levels of information. While we find that most parishes provided information related to the election, there is wide diversity in the types and sources of information. And, while the Catholic hierarchy attempted to provide messaging about the importance of political participation, not all parishes complied with these efforts. Our findings are consistent with the ideas that the local community and hierarchical structure combine to shape the behavior of the parishes.
Reduction of epileptiform activity in ketogenic mice: The role of monocarboxylate transporters
Authors: Forero-Quintero Linda S. , Deitmer Joachim W. , Becker Holger M. 
Published: July 2017

AbstractEpilepsy is a chronic neurological disorder that affects approximately 50 million people worldwide. Ketogenic diet (KD) can be a very effective treatment for intractable epilepsy. Potential mechanisms of action for KD have been proposed, including the re-balance among excitatory and inhibitory neurotransmission and decrease in the glycolytic rate in brain cells. KD has been shown to have an effect on the expression pattern of monocarboxylate transporters (MCT), however, it is unknown whether MCT transport activity is affected by KD and linked to the reduction of seizures during KD. Therefore, we studied the influence of KD on MCT transport activity and the role of MCTs during epileptiform activity. Our results showed a decrease in the epileptiform activity in cortical slices from mice fed on KD and in the presence of beta-hydroxybutyrate. KD increased transport capacity for ketone bodies and lactate in cortical astrocytes by raising the MCT1 expression level. Inhibition of MCT1 and MCT2 in control conditions decreases epileptiform activity, while in KD it induced an increase in epileptiform activity. Our results suggest that MCTs not only play an important role in the transport of ketone bodies, but also in the modulation of brain energy metabolism under normal and ketogenic conditions.
Evolution of the Araliaceae family inferred from complete chloroplast genomes and 45S nrDNAs of 10 Panax-related species
Authors: Kim Kyunghee , Nguyen Van Binh , Dong Jingzhou , Wang Ying , Park Jee Young , Lee Sang-Choon , Yang Tae-Jin 
Published: July 2017

AbstractWe produced complete sequences and conducted comparative analysis of the maternally inherited chloroplast (cp) genomes and bi-parentally inherited 45S nuclear ribosomal RNA genes (nrDNA) from ten Araliaceae species to elucidate the genetic diversity and evolution in that family. The cp genomes ranged from 155,993 bp to 156,730 bp with 97.1–99.6% similarity. Complete 45S nrDNA units were about 11 kb including a 5.8-kb 45S cistron. Among 79 cp protein-coding genes, 74 showed nucleotide variations among ten species, of which infA, rpl22, rps19 and ndhE genes showed the highest Ks values and atpF, atpE, ycf2 and rps15 genes showed the highest Ka/Ks values. Four genes, petN, psaJ, psbF, and psbN, related to photosynthesis and one gene, rpl23, related to the ribosomal large subunit remain conserved in all 10 Araliaceae species. Phylogenetic analysis revealed that the ten species could be resolved into two monophyletic lineages, the Panax-Aralia and the Eleutherococcus-Dendropanax groups, which diverged approximately 8.81–10.59 million years ago (MYA). The Panax genus divided into two groups, with diploid species including P. notoginseng, P. vietnamensis, and P. japonicus surviving in Southern Asia and a tetraploid group including P. ginseng and P. quinquefolius Northern Asia and North America 2.89–3.20 MYA.
Emerging novel electronic structure in hydrogen-Arsenene-halogen nanosheets: A computational study
Authors: Liu Ming-Yang , Li Ze-Yu , Chen Qing-Yuan , Huang Yang , Cao Chao , He Yao 
Published: July 2017

AbstractBased on first-principles calculations including spin-orbit coupling, we investigated the stability and electronic structure of unexplored double-side decorated arsenenes. It has been found that these new double-side decorated arsenenes, which we call “hydrogen-arsenene-halogen (H-As-X, X is halogen)”, are dynamically stable via the phonon dispersion calculations except H-As-F sheets. In particular, all of H-As-X nanosheets are direct band gap semiconductors with a strong dispersion near the Fermi level, which is substantially different from the previous works of double-side decorated arsenenes with zero band gaps. Our results reveal a new route to change the band gap of arsenene from indirect to direct. Furthermore, we also studied bilayer, trilayer, and multilayer H-As-Cl sheets to explore the effects of the layer number. The results indicate that bilayer, trilayer, and multilayer H-As-Cl sheets display novel electronic structure, namely multi-Dirac cones character, and the Dirac character depends sensitively on the layer number. It is noted that the frontier states near the Fermi level are dominantly controlled by the top and bottom layers in trilayer and multilayer H-As-Cl sheets. Our findings may provide the valuable information about the new double-side decorated arsenene sheets in various practical applications in the future.
Elastic properties of superconductors and materials with weakly correlated spins
Authors: Binek Christian 
Published: July 2017

AbstractIt is shown that in the ergodic regime, the temperature dependence of Young’s modulus is solely determined by the magnetic properties of a material. For the large class of materials with paramagnetic or diamagnetic response, simple functional forms of the temperature derivative of Young’s modulus are derived and compared with experimental data and empirical results. Superconducting materials in the Meissner phase are ideal diamagnets. As such, they display remarkable elastic properties. Constant diamagnetic susceptibility gives rise to a temperature independent elastic modulus for ceramic and single crystalline superconductors alike. The thermodynamic approach established in this report, paves the way to tailor elastic material parameters through the design of magnetic properties.
Electronically Switchable Broadband Metamaterial Absorber
Authors: Lee Dongju , Jeong Heijun , Lim Sungjoon 
Published: July 2017

AbstractIn this study, the novel electronically switchable broadband metamaterial absorber, using a PIN diode, is proposed. The unit cell of the absorber was designed with a Jerusalem-cross resonator and an additive ring structure, based on the FR-4 dielectric substrate. Chip resistors and PIN diodes were used to provide both a broadband characteristic and a switching capability. To satisfy the polarization insensitivity, the unit cell was designed as a symmetrical structure, including the DC bias network, electronic devices, and conductor patterns. The performance of the proposed absorber was verified using full-wave simulation and measurements. When the PIN diode was in the ON state, the proposed absorber had a 90% absorption bandwidth from 8.45–9.3 GHz. Moreover, when the PIN diode was in the OFF state, the 90% absorption bandwidth was 9.2–10.45 GHz. Therefore, the absorption band was successfully switched between the low-frequency band and the high-frequency band as the PIN diode was switched between the ON and OFF states. Furthermore, the unit cell of the proposed absorber was designed as a symmetrical structure, and its performance showed insensitivity with respect to the polarization angle.
Ginger Extract Modulates the Expression of Chemokines CCL20 and CCL22 and Their Receptors (CCR6 and CCR4) in the Central Nervous System of Mice with Experimental Autoimmune Encephalomyelitis
Authors: Jafarzadeh Abdollah , Arabi Zahra , Ahangar-Parvin Rayhaneh , Mohammadi-Kordkhayli Marziyeh , Nemati Maryam 
Published: July 2017

Abstract
Background Chemokines facilitate the leukocytes infiltration into the central nervous system (CNS) which is an essential step in the pathogenesis of multiple sclerosis. Ginger has also a broad anti-inflammatory properties. The aim was to evaluate the effects of ginger extract on the expression of CCL20 and CCL22 and their receptors (CCR6 and CCR4, respectively) in experimental autoimmune encephalomyelitis (EAE).
Material and Methods Female C57BL/6 mice used for EAE induction by immunization with myelin oligodendroglial glycoprotein. Then, the EAE mice were treated with PBS or ginger extract, from day +3 to +30. At day 31, mice were scarified and the expression of CCL20 and CCL22 and their receptors in the spinal cord measured using real time-PCR.
Results The expression of CCL20, CCL22 and CCR4 in the spinal cord of PBS-administrated EAE mice was significantly higher than healthy group (P<0.04, P<0.05 and P<0.02, respectively). In 200- and 300 mg/kg ginger extract-treated EAE mice, the expression of CCL20, CCL22 and CCR4 were significantly reduced as compared with PBS-administrated EAE group (P<0.04, P<0.01 and P<0.002 for 200 mg/kg ginger extract and P<0.01, P<0.005 and P<0.004 for 300 mg/kg ginger extract, respectively). The CCR6 expression in EAE mice treated with 200- or 300 mg/kg ginger extracts was lower than PBS-administrated EAE mice (P<0.01 and P=0.07, respectively).
Conclusion Treatment of EAE mice with ginger extract down-regulate the expression of CCL20 and CCL22 and their receptors in EAE mice. The possible therapeutic potential of ginger for treatment of MS can be considered in future investigations.
Analysis of a dual domain phosphoglycosyl transferase reveals a ping-pong mechanism with a covalent enzyme intermediate
Authors: Das Debasis , Kuzmic Petr , Imperiali Barbara 
Published: July 2017

Significance
Escalating antibiotic resistance has stimulated interest in understanding the mechanisms of phosphoglycosyl transferases (PGTs) that initiate glycoconjugate biosynthesis and are implicated in bacterial survival and pathogenicity. This study provides compelling evidence that the action of PglC, a prototypic dual domain PGT, proceeds through a unique covalent phosphosugar enzyme intermediate. Thus, the reaction course differs significantly from the mechanism of polytopic PGTs, illustrating nature’s ability to catalyze a biologically critical phosphosugar transfer reaction by two fundamentally different mechanisms. Dual domain PGTs, despite their widespread distribution throughout bacteria, have not been extensively studied to date. This analysis of dual domain PGTs will fuel approaches targeted at the development of small molecule inhibitors of critical first steps in bacterial glycoconjugate biosynthesis.
A sociocognitive model of interventions for writing instruction
Authors: Le Bouthillier Josée 
Published: July 2017

This summary reports on an ethnographic study conducted in French immersion concerning the writing development of at-risk and typically developing writers. Eight Grade 7 writers – four at-risk and four typically developing – were observed closely during classroom observations and participated in think-aloud protocols at the beginning and at the end of the school year 2012–2013 as well as in formal and informal interviews. In addition, the context in which those eight writers were learning to write was taken into consideration, therefore a total of 20 students participated in this study. Four teachers, the resource teacher, the counselor, and the two administrators were informants. Adopting a sociocognitive lense, the data reported here provide a detailed description of how the socioaffective, affective, and academic domains affected writing development, especially for at-risk writers. In order to respond to the affective and social needs of the writers of this study, a Sociocognitive Model of Interventions for Writing Instruction is proposed.
How subject animacy constrains motion event descriptions
Authors: Berthaud Sarah , Antonijević Stanislava 
Published: July 2017

AbstractResearch has indicated that during sentence processing, French native speakers predominantly rely upon lexico-semantic cues (i.e., animacy) while native speakers of English rely upon syntactic cues (i.e., word order). The present study examined sentence production in L1 French/L2 English and L1 English/L2 French sequential bilinguals. Participants used animate and inanimate entities as sentence subjects while describing motion events represented by static pictures. To test a gradual change in animacy cue weighting in second-language sequential bilinguals with different proficiency levels were included. Sentence production of sequential bilinguals was compared against that of simultaneous bilinguals. The results indicated an overall preference for the use of animate subjects for both languages at all proficiency levels. The effect of animacy was stronger for English L2 than French L2 while it did not differ between languages in simultaneous bilinguals. Evidence for potential change in the animacy-cue weighting was only observed for English L2.
Phylogenetic inferences on the systematics of squaliform sharks based on elasmobranch scapular morphology (Chondrichthyes: Elasmobranchii)
Authors: Da Silva João Paulo C B , Vaz Diego F B , de Carvalho Marcelo R 
Published: July 2017

AbstractThe scapulae of elasmobranchs project dorsolaterally from their fusion with the coracoid bar of the pectoral girdle, serving as anchoring points for the cucullaris, trunk and appendicular muscles and as articular points for the pectoral-fin skeleton. The scapulae of many elasmobranch taxa are described, with an emphasis on variations in the posterior margin, in an effort to reveal characters of phylogenetic relevance. In particular, phylogenetic information from the scapula was found for some squaliform sharks. Representatives of Dalatiidae, Somniosidae, Oxynotidae and Etmopteridae have a process on the ventral third of the posterior margin of the scapula, providing an additional surface for anchoring the origin of the appendicular muscle: the levator pectoralis. The ventral scapular process in Dalatiidae, Somniosus and Etmopterus is remarkably developed. This contrasts with an absent or weakly developed ventral triangular process observed in remaining squaliforms and other shark taxa. A single dorsal projection of the scapulae is restricted for Carcharhinidae and Centrophorus and provides an additional anchoring point for the m. epaxialis. Most representatives of Somniosidae (except Somniosus), Trigonognathus and some genera of Scyliorhinidae, Proscylliidae and Triakidae have both dorsal and ventral triangular processes. These structures are described and discussed in the context of previous morphological and molecular phylogenies of elasmobranchs.