bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glycidol, a Valuable Substrate for the Synthesis of Monoalkyl Glyceryl Ethers: A Simplified Life Cycle Approach
Authors: Ricciardi Maria , Passarini Fabrizio , Vassura Ivano , Proto Antonio , Capacchione Carmine , Cucciniello Raffaele , Cespi Daniele 
Published: April 2017

AbstractThe disposal of any waste by recovering it within the production plant represents the ultimate goal of every biorefinery. In this scenario, the selective preparation of monoalkyl glyceryl ethers (MAGEs) starting from glycidol, obtained as byproduct in the epichlorohydrin production plant, represents a very promising strategy. Here, we report the synthesis of MAGEs through the reaction of glycidol with alcohols catalyzed by a green homogeneous Lewis acids catalyst, such as BiIII triflate, under very mild reaction conditions. To evaluate the green potential of the proposed alternative, a simplified life cycle assessment (LCA) approach was followed by comparing the environmental performance of the proposed innovative route to prepare MAGEs with that of the most investigated pathway from glycerol. A considerable reduction of all impact categories considered was observed in our experimental conditions, suggesting that the glycidol‐to‐MAGEs route can be a valuable integration to the glycerol‐to‐MAGEs chain. Thanks to the use of primary data within the LCA model, the results achieved are a very good approximation of the real case.
Threshold voltage extraction techniques adaptable from sub‐micron CMOS to large‐area oxide TFT technologies
Authors: Samanta Smrutilekha , Tiwari Bhawna , Bahubalindruni Pydi Ganga , Barquinha Pedro , Goes Joao 
Published: April 2017

SummaryThis paper proposed simple and accurate threshold voltage (VTH) extraction techniques, which can be directly adaptable to various semiconductor technologies ranging from deep sub‐micron complementary metal–oxide–semiconductor to large‐area thin‐film transistor devices. These techniques are developed using multiple circuits, namely, a dynamic source follower, an inverter with a diode‐connected load and a current mirror topology, which allow a direct determination of VTH. As the proposed techniques are experimented with large‐area emerging technologies, which have a stable single type (n‐type) transistor, all the designs employed in this work are confined to only n‐type transistors for a fair comparison. The semiconductor technologies under consideration are standard complementary metal–oxide–semiconductor (65 and 130 nm) and oxide (indium–gallium–zinc–oxide and zinc–tin–oxide) thin‐film transistors. In order to validate the accuracy of the proposed techniques, extracted VTH from these methods are compared against the value from linear transfer characteristics. The resulting relative error is within 5%, reinforcing proposed techniques suitability to different semiconductor technologies ranging from deep sub‐micron to large‐area transistors. Copyright © 2017 John Wiley & Sons, Ltd.
Fine social aspiration: Twitter as a voice for cytopathology
Authors: Lepe M. , Gardner J. M. 
Published: April 2017

AbstractSocial media is an influential tool that has the power to transform cytopathology. Twitter is being used more and more to share cutting‐edge updates from pathology meetings (“live‐tweeting”). Modern smartphones can now take high resolution microscopic photographs and easily transmit them worldwide via Twitter, Facebook, and other social media, allowing cytopathologists to share educational pearls and discuss difficult cases on a global scale like never before. Social media also allows cytopathologists to share a behind‐the‐scenes look at their subspecialty with other physicians and even the non‐medical public, helping them to better understand the crucial importance of cytopathology in modern medicine. This could positively impact rapport with other specialties, influence policy making, and possibly even improve delivery of patient care. Rare disease patient communities are being formed by patients on Facebook. By joining and volunteering with these patient groups, cytopathologists would have further opportunity to interact directly with patients and their family members, explaining the role of cytopathology in patient care and helping patients to better understand their own diseases. Social media enables cytopathologists and their colleagues in other pathology subspecialties to easily and rapidly form a broad and diverse worldwide network with one another. The authors believe that this is the key to a bright future for our specialty, a strong unified global community of pathologists all working together for education, patient advocacy, and outstanding patient care. Social media can allow us to build that community, strengthen its bonds, and harness its power like never before in history. Diagn. Cytopathol. 2017;45:705–713. © 2017 Wiley Periodicals, Inc.
Flubromazolam – Basic pharmacokinetic evaluation of a highly potent designer benzodiazepine
Authors: Huppertz Laura M. , Moosmann Bjoern , Auwärter Volker 
Published: April 2017

Since their first appearance on the Internet in 2012, designer benzodiazepines established as an additional, quickly growing compound class among new psychoactive substances. Data regarding pharmacokinetic parameters, metabolism, and detectability for new compounds are limited or often not available. One of these compounds, flubromazolam (8‐bromo‐6‐(2‐fluorophenyl)‐1‐methyl‐4H‐[1,2,4]triazolo[4,3‐a][1,4]benzodiazepine), the triazolo‐analogue of flubromazepam, has been offered on the Internet from 2014 on. The purpose of the present study was to assess the period of detectability in biological samples along with preliminary basic pharmacokinetic parameters of the designer benzodiazepine flubromazolam. To investigate these, one of the authors ingested a capsule containing 0.5 mg of the drug. Metabolism studies and suitability tests for the detection with immunochemical assays were performed with the samples obtained from the self‐experiment and five authentic case samples. Flubromazolam and its mono‐hydroxylated metabolite were detectable by liquid chromatography–tandem mass spectrometry (LC–MS/MS) in urine for up to 6.5 and 8 days, respectively (lower limit of quantification (LLOQ) flubromazolam: 0.1 ng/mL). Peak serum concentrations were as low as 8 ng/mL (8 h post ingestion). Glucuronides were also detected. The terminal elimination half‐life could be estimated in the range of 10–20 h. Immunochemical assays yielded negative results for serum samples and positive results for urine samples for up to five days post ingestion. The presented data demonstrate the detectability of a single uptake of 0.5 mg of flubromazolam in hair samples collected two weeks after drug uptake by LC–MS3(cmax0.6 pg/mg; LOD 0.01 pg/mg). The detected metabolites were in good agreement with those described in other studies. Copyright © 2017 John Wiley & Sons, Ltd.
Brain morphology of the threespine stickleback (Gasterosteus aculeatus) varies inconsistently with respect to habitat complexity: A test of the Clever Foraging Hypothesis
Authors: Ahmed Newaz I. , Thompson Cole , Bolnick Daniel I. , Stuart Yoel E. 
Published: April 2017

AbstractThe Clever Foraging Hypothesis asserts that organisms living in a more spatially complex environment will have a greater neurological capacity for cognitive processes related to spatial memory, navigation, and foraging. Because the telencephalon is often associated with spatial memory and navigation tasks, this hypothesis predicts a positive association between telencephalon size and environmental complexity. The association between habitat complexity and brain size has been supported by comparative studies across multiple species but has not been widely studied at the within‐species level. We tested for covariation between environmental complexity and neuroanatomy of threespine stickleback (Gasterosteus aculeatus) collected from 15 pairs of lakes and their parapatric streams on Vancouver Island. In most pairs, neuroanatomy differed between the adjoining lake and stream populations. However, the magnitude and direction of this difference were inconsistent between watersheds and did not covary strongly with measures of within‐site environmental heterogeneity. Overall, we find weak support for the Clever Foraging Hypothesis in our study.
Seasonal abundance and habitat use of bird species in and around Wondo Genet Forest, south‐central Ethiopia
Authors: Girma Zerihun , Mamo Yosef , Mengesha Girma , Verma Ashok , Asfaw Tsyon 
Published: April 2017

AbstractThe habitat use and seasonal migratory pattern of birds in Ethiopia is less explored as compared to diversity studies. To this end, this study aimed at investigating the patterns of distribution related to seasonality and the effect of habitat characteristics (elevation, slope, and average vegetation height) on habitat use of birds of Wondo Genet Forest Patch. A stratified random sampling design was used to assess the avian fauna across the four dominant habitat types found in the study area: natural forest, wooded grassland, grassland, and agroforestry land. A point transect count was employed to investigate avian species richness and abundance per habitat type per season. Ancillary data, such as elevation above sea level, latitude and longitude, average vegetation height, and percent slope inclination, were recorded with a GPS and clinometers per plot. A total of 33 migratory bird species were recorded from the area, of which 20 species were northern (Palearctic) migrants while 13 were inter‐African migrants. There was a significant difference in the mean abundance of migratory bird species between dry and wet seasons (t = 2.13, p = .038, df = 44). The variation in mean abundance per plot between the dry and wet seasons in the grassland habitat was significant (t = 2.35, p = .051, df = 7). In most habitat types during both dry and wet seasons, omnivore birds were the most abundant. While slope was a good predictor for bird species abundance in the dry season, altitude and average vegetation height accounted more in the wet season. The patch of forest and its surrounding is an important bird area for migratory, endemic, and global threatened species. Hence, it is conservation priority area, and the study suggests that conservation coupled with ecotourism development is needed for its sustainability.
Lessons from a decade of lake management: effects of herbicides on Eurasian watermilfoil and native plant communities
Authors: Kujawa Ellen Ruth , Frater Paul , Mikulyuk Alison , Barton Martha , Nault Michelle E. , Van Egeren Scott , Hauxwell Jennifer 
Published: April 2017

AbstractEurasian watermilfoil (Myriophyllum spicatum) is a non‐native and invasive aquatic macrophyte with a broad North American distribution. It can have significant negative effects on invaded waterbodies, including decreased native macrophyte diversity, formation of recreational nuisances, and lowered lakefront property values. Previous research suggests that M. spicatum decreases in response to herbicide treatment, but most studies are spatially and temporally limited, usually focusing on a single waterbody for a single year. The long‐term effects of herbicides remain relatively unknown. Here, we share the results of an 11‐yr observational study of aquatic macrophyte diversity, dynamics, and response to herbicide treatment on 28 Wisconsin lakes (15 of which were adaptively managed with herbicide for M. spicatum and 13 of which acted as unmanaged reference lakes). We found that overall, adaptive management decreases M. spicatum abundance over time, but that the efficacy of individual herbicide treatments can vary. We also found that lakes with relatively new M. spicatum populations (discovered within the last decade) treated smaller areas with lower frequency than lakes with established populations, and were able to maintain lower M. spicatum abundance. This suggests that using adaptive, science‐based aquatic plant management strategies, including early detection and response, may increase invasive species management success. Finally, we show that the effect of herbicide treatment on native macrophytes is variable and can be significant. Overall, our results suggest that while herbicide treatment can be an effective adaptive management tool, particularly in lakes with relatively recent M. spicatum invasions, the specific effects of individual treatments can be unpredictable. This study allows lake stakeholders to better understand the efficacy of herbicide treatment, in addition to the possible non‐target effects on native macrophyte species.
Low‐level addition of dissolved organic carbon increases basal ecosystem function in a boreal headwater stream
Authors: Robbins Caleb J. , King Ryan S. , Yeager Alyse D. , Walker Coowe M. , Back Jeffrey A. , Doyle Robert D. , Whigham Dennis F. 
Published: April 2017

AbstractComprehension of basic stream ecosystem function relies on an understanding of aquatic–terrestrial linkages. One major component of such linkages is the incorporation of landscape‐derived energy and nutrients into the aquatic food web via microbes. In many boreal streams, wetlands and alder are known to be primary sources of dissolved organic carbon (DOC) and dissolved inorganic nitrogen (DIN), respectively. To simulate the influence of the highly labile portion of wetland‐derived DOC subsidies on microbial production and ecosystem processes in a stream with high landscape‐derived nutrient inputs, we enriched a boreal headwater stream situated in a high‐alder, low‐wetland cover catchment (i.e., high DIN, low DOC) with low levels (~0.25 mg/L) of labile DOC (as acetate‐C) for 9 weeks. We compared nutrient uptake, bacterial biomass production, and photosynthesis of periphyton and ecosystem metabolism in physicochemically similar upstream (reference) and downstream (treatment) reaches. DIN uptake was greater in the treatment than in reference reach on six out of nine dates during the dosing period. Bacterial biomass production positively responded to C enrichment. Ecosystem respiration increased up to ~50% after dosing began. Gross primary production responded positively to DOC enrichment early in the study when riparian vegetation did not limit light availability, but negatively later on in the growing season. We conclude that even low levels of labile DOC may act as a strong subsidy to headwater stream ecosystems, particularly those with high levels of DIN inputs from alder. Headwater streams influenced by high contributions of both alder and wetlands may represent biogeochemical hotspots, and these landscape features should be viewed as vital and complementary in their roles for ecosystem function.
Capital vs. income‐dependent optimal birth date in two North American ungulates
Authors: Hogg John T. , Dunn Stacey J. , Poissant Jocelyn , Pelletier Fanie , Byers John A. 
Published: April 2017

AbstractPhenotypic plasticity in reproductive traits is of theoretical and applied interest as one avenue by which organisms might maintain an optimal annual reproductive routine in the face of cyclic and/or directional change in environmental conditions. We used long‐term, individual‐based data from parapatric populations of bighorn sheep (Ovis canadensis canadensis) and pronghorn (Antilocapra americana) to evaluate plasticity in breeding date, gestation duration, birth date, birth mass, and fetal growth rate in response to inter‐annual (cyclic) variation in indices of maternal energy income and expense. Traits in both species responded plastically to variation in maternal energy balance. However, despite nearly identical climate and similar vegetative habitat, plasticity was expressed in fundamentally different ways in the study species. Variation in bighorn birth date was primarily due to plasticity in breeding date, whereas variation in pronghorn birth date was primarily due to variation in gestation duration. Across traits, bighorn plastic responses were more consistent with explanations that invoked periodic energy surplus as the basis for plasticity, whereas pronghorn plastic responses were more consistent with explanations that invoked periodic energy deficiency. Later birth date was associated with increased fetal growth rate in bighorn but decreased fetal growth rate in pronghorn. Finally, we detected strong directional selection for early birth among bighorn mothers but found no evidence of selection on pronghorn birth date. Collectively, our results indicate markedly different maternal tactics for timing birth. Bighorn mothers appeared to use stored energy to subsidize the cost of birth prior to the local environmental optimum in an energy‐mediated competition with other females to minimize birth order rank. Pronghorn mothers, committed to high levels of energy allocation to offspring and subject therefore to frequent energy deficiency, timed birth conservatively to more closely match peak reproductive expenditure with peak energy income at the local environmental optimum.
Increased resource availability prevents the disruption of key ecological interactions in disturbed habitats
Authors: Fontúrbel Francisco E. , Salazar Daniela A. , Medel Rodrigo 
Published: April 2017

AbstractAnthropogenic disturbance can modify habitat structure and resource availability, potentially disrupting ecological interactions. This issue may be critical for pollination and seed dispersal, which determine natural regeneration. The mistletoe Tristerix corymbosus is almost exclusively pollinated by a hummingbird (Sephanoides sephaniodes) and dispersed by a marsupial (Dromiciops gliroides). We examined the extent to which human‐induced habitat change and resource availability influence the interaction rate of this plant–pollinator–seed disperser system, along a forest transformation gradient (from native forest to exotic plantations). We estimated visitation rates of S. sephaniodes and D. gliroides on 70 T. corymbosus mistletoes using camera traps. We related visitation rates to habitat structural features and resource availability (flowers and fruits of the mistletoe and the neighborhood) using spatially explicit models. Sephanoides sephaniodes and D. gliroides visitation rates responded positively to shrub and bamboo cover, moss abundance, and mistletoe spatial arrangement. Pollination and seed dispersal interactions were sensitive to the flower and fleshy‐fruit neighborhoods, being variable across months. Further, D. gliroides showed a non‐random spatial association with fleshy‐fruited plants. A larger sunlight incidence on disturbed habitats may prevent the disruption of key ecological interactions by increasing resource availability. This effect would result from the presence of shade‐intolerant plants, which are benefited by sunlight exposure. Patches of disturbed habitat may enhance landscape heterogeneity, providing complementary resources to the native remnants.
Seasonal resource selection by introduced mountain goats in the southwest Greater Yellowstone Area
Authors: Lowrey B. , Garrott R. A. , Miyasaki H. M. , Fralick G. , Dewey S. R. 
Published: April 2017

AbstractMountain goats (Oreamnos americanus) are among the least studied North American ungulates. Aided by successful translocations from the early to mid‐1900s, introduced populations have greatly expanded within non‐native ranges, yet there remains a paucity of empirical studies concerning their habitat requirements and potential distributions. The lack of studies presents a formidable challenge to managers tasked with monitoring mountain goat expansion and mitigating for any potential negative impacts posed to native species and communities. We constructed summer and winter resource selection models using GPS data collected during 2011–2014 from 18 (14 female and four male) mountain goats in the Snake River Range of the southwest Greater Yellowstone Area. We used generalized linear mixed models and evaluated landscape and environmental covariates at multiple spatial grains (i.e., neighborhood analyses within 30‐, 100‐, 500‐, and 1000‐m buffers) within four related suites. The multi‐grain resource selection function greatly improved model fit, indicating that mountain goat resource selection was grain dependent in both seasons. In summer, mountain goats largely selected rugged and steep areas at high elevations and avoided high solar radiation, canopy cover, and time‐integrated normalized difference vegetation index (NDVI). In winter, mountain goats selected lower elevations characterized by steep and rugged slopes on warm aspects and avoided areas with high canopy cover, NDVI amplitude, and snow water equivalent. Slope was the dominant predictor of habitat use in both seasons, although mountain goats selected for steeper slopes in winter than in summer. Regional extrapolations depicted suitable mountain goat habitat in the Snake River, Teton, Gros Ventre, Wyoming, and Salt Ranges centered around steep and rugged areas. Winter range was generally characterized by the steepest slopes within a more broadly distributed and generally less steep summer range. Further research should examine the spatial and temporal overlap with native populations to further our understanding of resource selection dynamics and the potential for introduced mountain goats to alter intraguild behavioral processes of sympatric species, namely the Rocky Mountain bighorn sheep (Ovis canadensis canadensis).
Drought impact on forest regeneration in the SoutheastUSA
Authors: Hu Huifeng , Wang G. Geoff , Bauerle William L. , Klos Ryan J. 
Published: April 2017

AbstractElevating concentrations of atmospheric greenhouse gases are now widely acknowledged as a major cause of global warming. A warmer climate could increase the frequency, duration, and/or severity of drought and, in turn, could alter the composition, structure, and biogeography of forests in many regions. To explore the regional effects of different drought severities on forest regeneration, we investigated changes in sapling growth and density across the southeastern United States under various drought and stand conditions using 1991–2005 Forest Health and Monitoring plot data from Alabama, Georgia, and Virginia. Drought effects were examined on three species groups (pine, oak + hickory, and mesophytic species) using the Palmer Drought Severity Index. Stand and site variables, including total basal area, total stand density, tree species richness, slope, and stand age, were used to account for drought effects under varying stand conditions. The oak + hickory and mesophytic species groups exhibited significant reductions in annual growth rate with increasing drought severity. However, no significant difference in annual growth rate was observed within the pine species group. Chi‐square analysis showed that annual mortality rate was significantly dependent on drought severity for each species group but annual recruitment rate was only significantly dependent on drought severity for the oak + hickory group. Total basal area, tree species richness, and stand age had a negative effect on growth in one or more species groups. The observed differential dynamics of sapling growth, mortality, and recruitment among species groups may alter the trend of forest regeneration in southeastern U.S. forests because of the predicted increases in intensity and frequency of droughts in the future. The significant effects of stand conditions on drought responses observed in our study also suggest that appropriate forest management strategies may be useful to maintain structure features of understory saplings for southeastern U.S. forests.