bluuebunny/crossref_metadata_2025_split huggingface dataset:
High sensitivity troponin T and I reflect left atrial function being assessed by cardiac magnetic resonance imaging
Authors: Natale Michèle , Behnes Michael , Kim Seung-Hyun , Hoffmann Julia , Reckord Nadine , Hoffmann Ursula , Budjan Johannes , Lang Siegfried , Borggrefe Martin , Papavassiliu Theano , Bertsch Thomas , Akin Ibrahim 
Published: June 2017

Background Left atrial function (LAF) plays an interactive role between pulmonary and systemic circulation. Cardiac biomarkers, such as amino-terminal pro-brain natriuretic peptide (NT-proBNP) and troponins, might reflect cardiac function. This study aims to evaluate the association between high sensitivity troponins (hsTn) and left atrial function in patients undergoing cardiac magnetic resonance imaging (cMRI). Methods Patients undergoing cardiac magnetic resonance imaging (cMRI) were enrolled prospectively. Patients with right ventricular dysfunction (<50%) were excluded. Blood samples for measurements of hsTn and NT-proBNP were collected at the time of cMRI. Results Eighty-four patients were included. Median LVEF was 59% (IQR 51–64%). HsTn correlated inversely with LAF within multivariable linear regression models (hsTnI: Beta −0.46; T −4.44; P = 0.0001; hsTnT: Beta −0.29; T −3.06; P = 0.003). High sensitivity troponins increased significantly according to decreasing stages of impaired LAF ( P = 0.0001). High sensitivity troponins discriminated patients with impaired LAF < 55% (hsTnT: AUC = 0.80; P = 0.0001; hsTnI: AUC = 0.74; P = 0.0001) and <45% (hsTnT: AUC = 0.75; P = 0.0001; hsTnI: AUC = 0.73; P = 0.001) and were still significantly associated in multivariable logistic regression models (LAF < 55%: hsTnT: OR = 21.78; P = 0.0001; hsTnI: OR = 5.96; P = 0.009; LAF < 45%: hsTnT: OR = 10.27; P = 0.0001; hsTnI: OR = 12.56; P = 0.001). Conclusions This study demonstrates that hsTn are able to reflect LAF being assessed by cardiac magnetic resonance imaging.
Foetal haemoglobin concentration at postmenstrual age is unaffected by gestational age at birth
Authors: Watanabe Yuki , Osawa Kayo , Sato Itsuko , Iwatani Sota , Kono Ruri , Hayakawa Ikuyo , Hayashi Nobuhide , Iijima Kazumoto , Saegusa Jun , Morioka Ichiro 
Published: June 2017

Background Our aim was to determine whether the postnatal age or postmenstrual age is a more appropriate criterion for evaluating foetal haemoglobin concentrations. Methods Blood samples ( n = 1095) were obtained from 394 infants and were divided into two groups based on gestational age at birth: <37 weeks ( n = 491) and ≥37 weeks ( n = 604). (1) Foetal haemoglobin concentrations divided by one month at age after birth were compared between the groups. (2) Foetal haemoglobin concentrations divided into ≤9 months from last menstruation and one month thereafter were compared between the groups. Results In samples from infants ≥37 weeks’ gestational age at birth, the median foetal haemoglobin concentrations were 69.5%, 21.4% and 3.6% at 0–1 month, 2–3 months and ≥5 months after birth, respectively. The median foetal haemoglobin concentrations in infants <37 weeks’ gestational age at birth were 75.5%, 62.7% and 5.1% at 0–1 month, 2–3 months and ≥5 months after birth, respectively. The median foetal haemoglobin concentrations in infants <37 weeks’ gestational age at birth were significantly higher than that in infants ≥37 weeks’ gestational age at birth at all postnatal age points. (2) There was no significant difference between the groups at all age points after nine months of postmenstrual age: 72.5 and 75.3% at 9–10 months, 25.1 and 26.6% at 11–12 months and 5.5 and 4.6% at >13 months after last menstruation in infants ≥37 and <37 weeks’ gestational age at birth, respectively. Conclusions Evaluation of foetal haemoglobin concentrations at postmenstrual age is unaffected by gestational age at birth.
Exploring the Relationship of Task Performance and Physical and Cognitive Fatigue During a Daylong Light Precision Task
Authors: Yung Marcus , Manji Rahim , Wells Richard P. 
Published: June 2017

Objective: Our aim was to explore the relationship between fatigue and operation system performance during a simulated light precision task over an 8-hr period using a battery of physical (central and peripheral) and cognitive measures. Background: Fatigue may play an important role in the relationship between poor ergonomics and deficits in quality and productivity. However, well-controlled laboratory studies in this area have several limitations, including the lack of work relevance of fatigue exposures and lack of both physical and cognitive measures. There remains a need to understand the relationship between physical and cognitive fatigue and task performance at exposure levels relevant to realistic production or light precision work. Method: Errors and fatigue measures were tracked over the course of a micropipetting task. Fatigue responses from 10 measures and errors in pipetting technique, precision, and targeting were submitted to principal component analysis to descriptively analyze features and patterns. Results: Fatigue responses and error rates contributed to three principal components (PCs), accounting for 50.9% of total variance. Fatigue responses grouped within the three PCs reflected central and peripheral upper extremity fatigue, postural sway, and changes in oculomotor behavior. Conclusion: In an 8-hr light precision task, error rates shared similar patterns to both physical and cognitive fatigue responses, and/or increases in arousal level. Application: The findings provide insight toward the relationship between fatigue and operation system performance (e.g., errors). This study contributes to a body of literature documenting task errors and fatigue, reflecting physical (both central and peripheral) and cognitive processes.
Moving Glaciers: Remaking Nature and Mineral Extraction in Chile
Authors: Li Fabiana 
Published: June 2017

The controversial Pascua-Lama mining project, straddling the border between Chile and Argentina and operated by Canada’s Barrick Gold, gained international notoriety when the company proposed to “move” three glaciers located at the mine site. The glaciers variously appeared, changed form, and disappeared as the project was developed, presented to the public, subjected to various modifications, and ultimately put on hold. The environmental impact assessment process created an inventory of the landscape that turned nature into an object of environmental management. At the same time, the element of public participation embedded in Chile’s environmental impact legislation helped to mobilize local and international activism. El polémico proyecto minero de Pascua-Lama que maneja la empresa canadiense Barrick Gold en la frontera entre Chile y Argentina quedó sometido al escrutinio internacional cuando la empresa propuso “mover” tres glaciares situados en la mina. Los glaciares aparecieron, cambiaron de forma y desaparecieron conforme el proyecto se desarrollaba, presentaba ante el público y era sometido a diversas modificaciones; en última instancia, fue suspendido. El proceso de evaluación de impacto ambiental dio lugar a un inventario del paisaje que convirtió a la naturaleza en un objeto de gestión ambiental. Al mismo tiempo, la participación ciudadana fundamentada en la legislación chilena de impacto ambiental ayudó a movilizar activistas locales e internacionales.
Insight et comportements violents dans une cohorte de patients souffrant de premiers épisodes de psychose
Authors: Moulin Valerie , Palix Julie , Alameda Luis , Gholamrezaee M. Mehdi , Baumann Philipp S. , Gasser Jacques , Elowe Julien , Solida Alessandra , Conus Philippe 
Published: June 2017

Objectifs: Une proportion importante de patients présentant un premier épisode psychotique commettent des actes violents hétéro-agressifs. L’objectif de cette étude est d’explorer l’association entre insight et comportement violent (CV) et l’évolution de l’insight durant la période de suivi. Méthode: L’étude est conduite sur une cohorte prospective de 265 patients recrutés au sein du programme de traitement et d’intervention précoce dans les troubles psychotiques et suivis sur une période de 3 ans. L’évaluation de l’insight est basée sur une échelle d’insight en 3 points et l’item de l’insight à la Positive and Negative Syndrome Scale (PANSS). Les CV ont été évalués par les case-managers, par les informations provenant des services forensiques et par l’intermédiaire d’un relevé des CV en cours d’hospitalisation. Des analyses de régression logistique uni-variées et multi-variées, des tests-t et des corrélations ont été réalisés. Résultats: L’effet significatif de l’insight comme facteur associé aux CV trouvé dans les analyses uni-variées disparaît après avoir contrôlé l’effet des symptômes positifs, du diagnostic de dépendance aux substances, de l’impulsivité et de l’adhésion au traitement. Conclusion: Si la prise de conscience des patients à l’égard de leur maladie évolue positivement au cours du traitement, nos résultats suggèrent que le risque de survenue de CV n’est pas influencé par le degré d’insight. Il est par contre significativement lié à l’abus de substances et à l’impulsivité, impliquant de cibler ces deux dimensions dans les stratégies préventives. L’impact de l’insight sur le CV doit être l’objet d’analyses prospectives plus précises.
Impact of Generalized Joint Laxity on Plantar Loading Patterns in Young Females
Authors: Aydın Elif , Metin Tellioğlu Ayfer , Kurt Ömürlü Imran , Turan Yasemin 
Published: June 2017

Background: Generalized joint laxity is often associated with gait deviations. The aim of this study was to investigate the static and dynamic loading pattern of the foot with increasing joint mobility and to discuss the potential impact of this condition on the plantar loading patterns. Methods: Seventy female participants between ages of 18 and 30 were included in this cross-sectional survey. The Beighton-Horan Joint Mobility Index scores were assessed and participants divided into 3 categories: no hypermobility (NH) group, scores 0 to 2; moderate hypermobility (MH) group, scores 3 to 4; distinct hypermobility (DH) group, scores 5 to 9. Pedobarographic analysis was performed both in static and walking conditions. Dynamic foot loading examined in 10 anatomic zones. Contact areas of forefoot, midfoot, and rearfoot were recorded. Results: In the dynamic pedobarographic analysis, individuals with distinct joint hypermobility displayed higher peak pressure and maximum force values under the hallux, compared with other groups ( P < .05). The maximum force value of the second metatarsal was higher in the DH group than in the MH group ( P < .05). Conclusion: Our study results suggest that plantar loading pattern differs with increasing degrees of the hypermobility score. Clinical Relevance: Differences in plantar loading parameters in people with severe joint mobility scores may be useful in interpreting the foot pathologies of these individuals.
Potential Benefits of Ameliorating Metabolic and Nutritional Abnormalities in People With Profound Developmental Disabilities
Authors: Glick Norris R , Fischer Milton H 
Published: June 2017

Background: People with profound developmental disabilities have some of the most severe neurological impairments seen in society, have accelerated mortality due to huge medical challenges, and yet are often excluded from scientific studies. They actually have at least 2 layers of conditions: (1) the original disability and (2) multiple under-recognized and underexplored metabolic and nutritional imbalances involving minerals (calcium, zinc, and selenium), amino acids (taurine, tryptophan), fatty acids (linoleic acid, docosahexaenoic acid, arachidonic acid, adrenic acid, Mead acid, plasmalogens), carnitine, hormones (insulinlike growth factor 1), measures of oxidative stress, and likely other substances and systems. Summary: This review provides the first list of metabolic and nutritional abnormalities commonly found in people with profound developmental disabilities and, based on the quality of life effects of similar abnormalities in neurotypical people, indicates the potential effects of these abnormalities in this population which often cannot communicate symptoms. Key messages: We propose that improved understanding and management of these disturbed mechanisms would enhance the quality of life of people with profound developmental disabilities. Such insights may also apply to people with other conditions associated with disability, including some diseases requiring stem cell implantation and living in microgravity.
Novel variants in NUDT15 and thiopurine intolerance in children with acute lymphoblastic leukemia from diverse ancestry
Authors: Moriyama Takaya , Yang Yung-Li , Nishii Rina , Ariffin Hany , Liu Chengcheng , Lin Ting-Nien , Yang Wenjian , Lin Dong-Tsamn , Yu Chih-Hsiang , Kham Shirley , Pui Ching-Hon , Evans William E. , Jeha Sima , Relling Mary V. , Yeoh Allen Eng-Juh , Yang Jun J. 
Published: June 2017

Key Points
We identified 3 novel loss-of-function variants in NUDT15 linked to thiopurine intolerance. Our findings extended the importance of NUDT15 variation in thiopurine pharmacogenetics in diverse populations.
Factor VIIa interaction with EPCR modulates the hemostatic effect of rFVIIa in hemophilia therapy: mode of its action
Authors: Keshava Shiva , Sundaram Jagan , Rajulapati Anuradha , Esmon Charles T. , Pendurthi Usha R. , Rao L. Vijaya Mohan 
Published: June 2017

Key PointsEPCR levels influence the hemostatic effect of rFVIIa in hemophilia therapy. FVIIa binding to EPCR influences the hemostatic effect of FVIIa because of downregulation of protein C anticoagulation pathway.
Variation in rice root traits assessed by phenotyping under drip irrigation
Authors: Parthasarathi T. , Vanitha K. , Mohandass S. , Vered Eli , Meenakshi V. 
Published: June 2017

Background: Roots are the key elements in water saving rice cultivation. So, the response of rice roots are to be phenotyped under varied drip irrigation treatments. Methods: This study describes an investigation on rice root phenotyping under drip irrigation treatments in split-split plot design. Two lateral spacing levels (0.8 and 1.2m), laid at two depths of sub surface irrigation (5-10 and 15-20 cm) by solar powered and well operated irrigation were tested using TNRH 180, JKRH 3333 and ADT(R)45 rice genotypes during the summer season (2013 & 2014) in Coimbatore, India. Conventional aerobic irrigation was considered as control. Results and Discussion: An increased root length, root density (length and weight), root Adinosine Tri Phosphotase enzyme activity, root volume and filled grain percentage were favored in aerobic rice under the conditions of 0.8m lateral distance with 5-10cm depth of sub surface drip irrigation (SDI). Improved root characteristics were observed in JKRH 3333 rice hybrid, and root density and thickness favored the filled grains and yield increment in rice by drip irrigation. The 0.8m lateral distance laid out at 5-10cm depth SDI with solar system proliferated more roots at subsurface soil layer with significant yield increment in rice.
CORPORATE SOCIAL RESPONSIBILITY FOR THE INSTITUTE'S STRATEGIC DEVELOPMENT
Authors: Резник Семен , Reznik Semen 
Published: June 2017

The article reveals the essence of the concept of social responsibility,
presents the main areas of involvement of business
structures in socially-oriented activities, gives the results of its study
on the example of Russian enterprises, identifies specific features of
social marketing in Russia and offers recommendations for integrating
the social component in the strategy of commercial companies.
THE STRATEGY OF INVESTMENT AND INNOVATIVE ORGANIZATION DEVELOPMENT ON THE BASIS OF THE ANALYSIS OF INVESTMENT APPEAL
Authors: Новичкова  , Novichkova Ol'ga 
Published: June 2017

In this article special attention is paid to questions of investment
appeal of the organization in the conditions of the changing
economic conditions, both in the country, and in the world. On
the basis of the analysis of an investment potential the strategy of
investment and innovative development of the entity within forming
of the fundamental purposes and tasks on a long-term basis is
offered. By means of the developed strategy accurate determination
of a rate of actions and competent resource allocations is performed,
as will promote achievement of an effective objective.
Addition of Glute-Ham-Gastroc Raise to a Resistance Training Program: Effect on Jump Propulsion and Landing
Authors: Chiu Loren Z.F. , Yaremko Anita , vonGaza Gabriella L. 
Published: June 2017

Abstract
Chiu LZF, Yaremko A, and vonGaza GL. Addition of glute-ham-gastroc raise to a resistance training program: effect on jump propulsion and landing. J Strength Cond Res 31(9): 2562–2571, 2017—Exercises such as squats and cleans are commonly used in resistance training programs to enhance athletic performance. However, these exercises may not effectively train the gastrocnemius, an important muscle for energy generation and absorption. The purpose of this research was to examine the effects of adding glute-ham-gastroc raise exercise to target the gastrocnemius to a traditional resistance training program involving squats and cleans. Vertical jump height, weight-bearing ankle dorsiflexion, and jump propulsion and landing mechanics were examined before and after an 8-week training intervention in female youth volleyball players. Approach (with: ∆ = 2.6 ± 1.7 cm; 90% confidence interval [CI] [1.8–3.6 cm] vs. without: ∆ = 1.8 ± 1.9 cm; 90% CI [0.8–2.8 cm]) and standing (with: ∆ = 2.7 ± 1.7 cm; 90% CI [1.7–3.6 cm] vs. without: ∆ = 1.6 ± 1.5 cm; 90% CI [0.8–2.4 cm]) vertical jump height increased more in the group performing glute-ham-gastroc raise. Weight-bearing ankle dorsiflexion increased when glute-ham-gastroc raise was included (left: ∆ = 4.1 ± 4.1°; 90% CI [1.9–6.4°] and right: ∆ = 4.1 ± 3.9°; 90% CI [1.9–6.2°]) but did not appear to change with resistance training only (left: ∆ = 1.4 ± 4.5°; 90% CI [−1.0 to 3.9°] and right: ∆ = 2.5 ± 4.4°; [−0.3 to 4.5°]). No discernible differences were observed for changes in jump propulsion and landing mechanics between groups. Glute-ham-gastroc raise may have a beneficial effect with young athletes when added to squat- and clean-based resistance training programs.
The National Football League Combine 40-yd Dash: How Important is Maximum Velocity?
Authors: Clark Kenneth P. , Rieger Randall H. , Bruno Richard F. , Stearne David J. 
Published: June 2017

Abstract
Clark, KP, Rieger, RH, Bruno, RF, and Stearne, DJ. The NFL combine 40-yard dash: how important is maximum velocity? J Strength Cond Res 33(6): 1542–1550, 2019—This investigation analyzed the sprint velocity profiles for athletes who completed the 40-yard (36.6 m) dash at the 2016 National Football League (NFL) Combine. The purpose was to evaluate the relationship between maximum velocity and sprint performance, and to compare acceleration patterns for fast and slow athletes. Using freely available online sources, data were collected for body mass and sprint performance (36.6 m time with split intervals at 9.1 and 18.3 m). For each athlete, split times were used to generate modeled curves of distance vs. time, velocity vs. time, and velocity vs. distance using a monoexponential equation. Model parameters were used to quantify acceleration patterns as the ratio of maximum velocity to maximum acceleration (vmax
/amax
, or τ). Linear regression was used to evaluate the relationship between maximum velocity and sprint performance for the entire sample. In addition, athletes were categorized into fast and slow groups based on maximum velocity, with independent t-tests and effect size statistics used to evaluate between-group differences in sprint performance and acceleration patterns. Results indicated that maximum velocity was strongly correlated with sprint performance across 9.1, 18.3, and 36.6 m (r
2 of 0.72, 0.83, and 0.94, respectively). However, both fast and slow groups accelerated in a similar pattern relative to maximum velocity (τ = 0.768 ± 0.068 seconds for the fast group and τ = 0.773 ± 0.070 seconds for the slow group). We conclude that maximum velocity is of critical importance to 36.6 m time, and inclusion of more maximum velocity training may be warranted for athletes preparing for the NFL Combine.
Evaluation of the Official Match External Load in Soccer Players With Cerebral Palsy
Authors: Yanci Javier , Castillo Daniel , Iturricastillo Aitor , Reina Raul 
Published: June 2017

Abstract
Yanci, J, Castillo, D, Iturricastillo, A, and Reina, R. Evaluation of the official match external load in soccer players with cerebral palsy. J Strength Cond Res 33(3): 866–873, 2019—The aims of this study were to analyze the official match external loads (i.e., total distance, distance covered at different speeds, accelerations, decelerations, player load [PL], peak metabolic power, and changes of direction [CODs]) of football players with cerebral palsy (CP) and to determine the external loads according to playing time (i.e., <20, 20–40, and >40 minutes). The external load of 31 international football players with CP (23.0 ± 6.6 years; 69.1 ± 9.0 kg; 174.8 ± 7.3 cm) was analyzed during a World Championship Qualification Tournament (n = 8 matches, 58 individual observations). Results showed that the football players with CP covered less distance at high-intensity running and sprinting, performing a smaller number of moderate and high-intensity accelerations and decelerations, had a lower PL, and performed fewer CODs in official matches compared with conventional football players as reported in other studies. The number of minutes played by the players (i.e., <20, 20–40, and >40 minutes) could significantly influence the players' match external load (effect size = 0.3–5.5, small to extremely large). The impairments presented by football players with CP affect players' match external loads, especially in short-term high-intensity neuromuscular actions.
Components of Fatigue: Mind and Body
Authors: Carriker Colin R. 
Published: June 2017

Abstract
Carriker, CR. Components of fatigue: mind and body. J Strength Cond Res 31(11): 3170–3176, 2017—Maximal intensity exercise requires significant energy demand. Subsequently, prolonged high-intensity effort eventually initiates volitional cessation of the event; often preceeded by a sensation of fatigue. Those examining the basis of fatigue tend to advocate either a peripheral or central model to explain such volitional failure. Practitioners and athletes who understand the tenants of fatigue can tailor their exercise regimens to target areas of potential physical or mental limitation. This review examines the rationale surrounding 2 separate models which postulate the origination of fatigue. Although the peripheral model suggests that fatigue occurs at the muscles, others have suggested a teloanticipatory cognitive component which plays a dominant role. Those familiar with both models may better integrate practice-based evidence into evidence-based practice. The highly individual nature of human performance further highlights the compulsion to comprehend the spectrum of fatigue, such that the identification of insufficiencies should mandate the development of a training purview for peak human performance.
Reverse Lunge With Single-Arm Kettlebell Overhead Press
Authors: Handy Richard , Kerksick Chad 
Published: June 2017

ABSTRACT
THE REVERSE LUNGE WITH SINGLE-ARM KETTLEBELL OVERHEAD PRESS IS A GROUND-BASED EXERCISE THAT CHALLENGES THE FRONTAL AND SAGITTAL PLANES. INCORPORATION OF THE MOVEMENT CAN AID IN DEVELOPING STRENGTH AND POWER WHILE ALSO REDUCING INJURY RISK. THIS ARTICLE WILL DISCUSS THE MUSCLES ACTIVATED, PROPER EXERCISE TECHNIQUE, BENEFITS, AND ITS PRACTICAL APPLICATION.