bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiac Autonomic and Neuromuscular Responses During a Karate Training Camp Before the 2015 Pan American Games: A Case Study With the Brazilian National Team
Authors: Nakamura Fabio Y. , Pereira Lucas A. , Abad César C. Cal , Franchini Emerson , Loturco Irineu 
Published: December 2015

Purpose:To quantify the training loads reported by karate athletes of the Brazilian national team in the week immediately before their participation in the 2015 Pan American Games.Methods:Eleven elite karate athletes (7 men and 4 women, 24.42 ± 3.75 y, 1.70 ± 0.09 m, 69.6 ± 13.2 kg) from the Brazilian national team took part in this study. Session rating of perceived exertion (s-RPE) was quantified in all training sessions. Moreover, resting heart-rate variability (HRV), as analyzed through the natural log of the root-mean-square difference of successive normal RR intervals (lnRMSSD), and countermovement-jump (CMJ) performance before and after 8 training sessions were assessed throughout the week. The differences based on magnitudes were calculated comparing pre- and posttraining session, as well as measures performed every morning during the week.Results:The weekly s-RPE was 2608.5 ± 431.2 a.u. The lnRMSSD was very likely higher on Monday than on the following days of the week, remaining stable during this period. CMJ height did not change during the week. Almost certain differences were observed in lnRMSSD pre- and posttraining session, while CMJ height did not change.Conclusions:The national karate-team athletes did not present signs of fatigue accumulation, as indicated by relatively steady HRV and unchanged CMJ during the week, as planned by the coaches for precompetition technical and tactical refinement.
Complete Genome Sequence of Aneurinibacillus migulanus E1, a Gramicidin S- and
d
-Phenylalanyl-
l
-Propyl Diketopiperazine-Deficient Mutant
Authors: Belbahri Lassaad , Alenezi Faizah N. , Luptakova Lenka , Rateb Mostafa E. , Woodward Steve 
Published: December 2015

ABSTRACT

We report here the complete genome sequence of the
Aneurinibacillus migulanus
E1 mutant deficient in gramicidin S (GS) and
d
-phenylalanyl-
l
-propyl diketopiperazine (DKP) formation. The genome consists of a circular chromosome (6,301,904 bp, 43.20% G+C content) without any plasmid. The complete genome sequence enables further investigation of the biosynthetic mechanism and the biological function of gramicidin S.
Draft Genome Sequence of Thermophilic
Geobacillus
sp. Strain Sah69, Isolated from Saharan Soil, Southeast Algeria
Authors: Bezuidt Oliver K. I. , Makhalanyane Thulani P. , Gomri Mohamed A. , Kharroub Karima , Cowan Don A. 
Published: December 2015

ABSTRACT

Geobacillus
spp. are potential sources of novel enzymes, such as those involved in the degradation of recalcitrant polymers. Here, we report a
Geobacillus
genome that may help reveal genomic differences between this strain and publicly available representatives of the same genus from diverse niches.
Draft Genome Sequences of Six
Pseudoalteromonas
Strains, P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25, and P1-26, Which Induce Larval Settlement and Metamorphosis in
Hydractinia echinata
Authors: Klassen Jonathan L. , Wolf Thomas , Rischer Maja , Guo Huijuan , Shelest Ekaterina , Clardy Jon , Beemelmanns Christine 
Published: December 2015

ABSTRACT

To gain a broader understanding of the importance of a surface-associated lifestyle and morphogenic capability, we have assembled and annotated the genome sequences of
Pseudoalteromonas
strains P1-7a, P1-9, P1-13-1a, P1-16-1b, P1-25, and P1-26, isolated from
Hydractinia echinata
. These genomes will allow detailed studies on bacterial factors mediating interkingdom communication.
Next-Generation Whole-Genome Sequencing of Eight Strains of Bacillus cereus, Isolated from Food
Authors: Krawczyk Antonina O. , de Jong Anne , Eijlander Robyn T. , Berendsen Erwin M. , Holsappel Siger , Wells-Bennik Marjon H. J. , Kuipers Oscar P. 
Published: December 2015

ABSTRACT

Bacillus cereus
can contaminate food and cause emetic and diarrheal foodborne illness. Here, we report whole-genome sequences of eight strains of
B. cereus
, isolated from different food sources.
Draft Genome Sequence of Francisella tularensis Strain 410108 from Tibet, China
Authors: Song Lihua , Yu Yonghui , Feng Le , Wang Tao , He Jun , Zhu Hong , Duan Qing 
Published: December 2015

ABSTRACT

Francisella tularensis
is the etiological agent of the potentially fatal disease tularemia. Here, we report the draft genome sequence of a virulent human isolate from Tibet, China in 1962,
F. tularensis
strain 410108, an intermediate-genotype strain of
F. tularensis
subsp.
holarctica
between biovar
japonica
and non-
japonica
strains in the world.
Early postdisaster health outreach to modern families: a cross-sectional study
Authors: Haga Jon Magnus , Stene Lise Eilin , Wentzel-Larsen Tore , Thoresen Siri , Dyb Grete 
Published: December 2015

ObjectivesThis study investigated whether the early outreach programme following the Utøya massacre reached out to the parents of the young survivors. Additionally, we explored whether specialised mental healthcare services were provided to parents presenting elevated levels of PTSD and depression reactions.DesignCross-sectional survey, face-to-face interviews and questionnaires.SettingNorway, aftermath of the Utøya massacre, 4–7 months postdisaster.BackgroundFollowing the Utøya massacre, proactive early outreach programmes were launched in all municipalities that were affected, facilitating access to appropriate healthcare services.ParticipantsA total of 453 parents of the Utøya survivors aged 13–33 years took part. Overall, 59.8% of the survivors were represented by one or more parent in our study.Main outcome measuresEngagement with the proactive early outreach programme (psychosocial crisis teams and contact persons in the municipalities), utilisation of healthcare services (general practitioner and specialised mental healthcare services) and mental distress (UCLA PTSD-RI and HSCL-8).ResultsA majority of the participants reported contact with the proactive early outreach programme (crisis team, 73.9%; and contact person, 73.0%). Failure of outreach to parents was significantly associated with non-intact family structure (crisis team: OR 1.69, 95% CI 1.05 to 2.72, p=0.032) and non-Norwegian origin (crisis team: OR 2.39, 95% CI 1.14 to 4.98, p=0.021). Gender of the parent was not significantly associated with failure of the outreach programme (p≥0.075). Provision of specialised mental healthcare services was significantly associated with higher levels of PTSD (OR 2.08, 95% CI 1.55 to 2.79, p<0.001) and depression (OR 2.42, 95% CI 1.71 to 3.43, p<0.001) and not with the sociodemography (p≥0.122).ConclusionsProactive early outreach strategies may be helpful in identifying healthcare needs and facilitating access to the required services in a population struck by disaster. Our findings prompt increased attention to the complexity of family structures in reaching out universally to modern families following a disaster.
Invention and Diffusion of Water Supply and Water Efficiency Technologies: Insights from a Global Patent Dataset
Authors: Conway Declan , Dechezleprêtre Antoine , Haščič Ivan , Johnstone Nick 
Published: December 2015

This paper identifies over 50,000 patents filed worldwide in various water-related technologies between 1990 and 2010, distinguishing between those related to availability (supply) and conservation (demand) technologies. Patenting activity is analyzed — including inventive activity by country and technology, international diffusion of such water-related technologies, and international collaboration in technology development. Three results stand out from our analysis. First, although inventive activity in water-related technologies has been increasing over the last two decades, this growth has been disproportionately concentrated on supply-side technologies. Second, whilst 80% of water-related invention occurs worldwide in countries with low or moderate water scarcity, several countries with absolute or chronic water scarcity are relatively specialized in water efficiency technologies. Finally, although we observe a positive association between water scarcity and local filings of water patents, some countries with high water availability, in particular Switzerland or Norway, nevertheless appear as significant markets for water-efficiency technologies. This suggests that drivers other than local demand, like regulation and social and cultural factors, play a role in explaining the global flows of technologies.
Late Maastrichtian foraminiferal response to sea-level change and organic flux, Central Graben area, Danish North Sea
Authors: Rasmussen Jan A. , Sheldon Emma 
Published: December 2015

Abstract

Foraminiferal palaeoecological analyses were carried out on 124 upper Maastrichtian chalk samples from the M-10X and E-5X wells of the Danish Central Graben. The two wells demonstrate similar trends, with some notable differences. Both are strongly dominated by planktic foraminifers, of which the small, biserial
Heterohelix globulosa
is by far the most common species. Based on variations within five significant, benthic foraminiferal morphogroups and the plankton/benthos ratio, eight specific foraminiferal intervals have been described. The faunal and palaeoenvironmental changes observed during the late Maastrichtian period were, in most places and especially in the lower part, not very distinct, and it is believed that the palaeoenvironment during the majority of the interval was a mostly stable, deep outer-shelf environment characterized mainly by pelagic sedimentation under temperate, suboxic conditions. More unstable conditions characterized the latest Maastrichtian. The analyses show that the sediments in the M-10X well were deposited in a generally deeper palaeoenvironment than those from E-5X. The influx of common
Pseudotextularia elegans
(three acmes), together with scattered specimens of the typical Tethyan species
Abathomphalus mayaroensis
and
Pseudoguembelina hariaensis
(in E-5X only), indicate that relatively warm conditions prevailed, at least periodically, during the latest part of the late Maastrichtian in both areas.
The gas membrane sensor (GMS) method: a new analytical approach for real-time gas concentration measurements in volcanic lakes
Authors: Zimmer Martin , Tassi Franco , Vaselli Orlando , Kujawa Christian , Cabassi Jacopo , Erzinger Joerg 
Published: December 2015

Abstract

The primary goal of this study was to apply an innovative analytical method based on a gas membrane sensor (GMS) to quantify the concentrations of CO
2
and CH
4
gas in water columns from volcanic lakes. For this purpose, dissolved CO
2
and CH
4
from the Monticchio Grande and Piccolo (Mt Vulture, Italy) and Pavin (Massif Central, France) lakes, characterized by depths of 35, 38 and 92 m, respectively, were measured using two different approaches: GMS and SH (single hose), the latter being an independent conventional method.

The CO
2
and CH
4
concentrations recorded via the GMS and SH techniques were within the analytical errors of the two methods. These test measurements demonstrated that the GMS method can be successfully used to produce highly accurate
in situ
measurements of dissolved gas composition along the vertical profiles of lakes.
Variable Phonological Rules and ‘Quantal' Perception as a Source of Probabilistic Sound Change: The Case of Intervocalic Voicing in Old Tuscan
Authors: Canalis Stefano 
Published: December 2015

Abstract
The origin and nature of ‘irregular', ‘sporadic' sound changes have been debated by different theories of phonological change since at least the Neogrammarians. They are often attributed to non-phonological factors, as analogy or borrowing, or to the non-(purely)-phonological mechanism of lexical diffusion. The aim of this paper is to show that an irregular sound change in the historical phonology of Tuscan - namely the voicing of some intervocalic voiceless stops - is not due to borrowing (as often argued), but to a variable and allophonic voicing rule, whose output was only partially subject to phonological recategorization. The most likely causes for this irregular outcome are the variable strength intervocalic voicing had in different environments, the interaction with another lenition process and the perceptual ambiguity of the lenited stops.
Portuguese Lexical Clusters and CVC Sequences in Speech Perception and Production
Authors: Cunha Conceição 
Published: December 2015

AbstractThi s paper investigates similarities between lexical consonant clusters and CVC sequences differing in the presence or absence of a lexical vowel in speech perception and production in two Portuguese varieties. The frequent high vowel deletion in the European variety (EP) and the realization of intervening vocalic elements between lexical clusters in Brazilian Portuguese (BP) may minimize the contrast between lexical clusters and CVC sequences in the two Portuguese varieties. In order to test this hypothesis we present a perception experiment with 72 participants and a physiological analysis of 3-dimensional movement data from 5 EP and 4 BP speakers. The perceptual results confirmed a gradual confusion of lexical clusters and CVC sequences in EP, which corresponded roughly to the gradient consonantal overlap found in production.
Interaction of Hereditary Thrombophilia and Traditional Cardiovascular Risk Factors on the Risk of Arterial Thromboembolism
Authors: Mahmoodi Bakhtawar K. , Veeger Nic J.G.M. , Middeldorp Saskia , Lijfering Willem M. , Brouwer Jan-Leendert P. , ten Berg Jur , Hamulyák Karly , Meijer Karina 
Published: December 2015

Background—
Hereditary thrombophilia is associated with a slightly increased risk of arterial thromboembolism (ATE). Whether hereditary thrombophilia interacts with traditional cardiovascular risk factors on the risk of ATE has yet to be established.

Methods and Results—

A total of 1891 individuals belonging to 4 family cohorts from the Netherlands were included in the analyses. Five hereditary thrombophilic defects, including factor V Leiden, prothrombin G20210A defect, and deficiencies of the natural anticoagulants (ie, antithrombin, protein C, and protein S), were assessed, and data on risk factors and previous ATE were collected. Thrombophilia was associated with elevated risk of ATE (hazard ratio =1.74, 95% confidence interval, 1.18–2.58;
P
=0.005). Overall, the association of thrombophilia with ATE tended to be stronger in the presence of traditional cardiovascular risk factors, especially the synergistic effect of thrombophilia with diabetes mellitus was striking (hazard ratio of thrombophilia–ATE association was 1.41 in nondiabetics versus 8.11 in diabetics). Moreover, the association of thrombophilia with ATE tended to be stronger in females and before the age of 55 years as compared with males and individuals >55 years of age, respectively.

Conclusions—
Thrombophilia is associated with ATE. This association may be stronger in the presence of traditional cardiovascular risk factors in particular in individuals with diabetes mellitus. Future studies on thrombophilia–ATE risk should focus on high-risk populations with high prevalence of traditional cardiovascular risk factors.
Sacred vessels: British church ship models
Authors: Greiling Meredith 
Published: December 2015

What is the significance of ship models hanging in British churches today? What is their function and what can they tell us about maritime culture, trade, and art in the context of the church through the ages? My doctoral research will examine the purpose and prevailing contemporary interpretation of ship models in Scottish churches and how these have altered from pre-Reformation church practice to the present day. Through a chronological study of the geographical spread of the practice of hanging ship models in churches, and by examining the folklore of the sculpture within a church context, my research explores the societies and individuals that commissioned these unique forms of sculpture and for what purpose, how the public’s interpretation of ship models in churches has developed and how the historical value placed on them has changed in recent years.
Nosocomial feline calicivirus-associated virulent systemic disease in a veterinary emergency and critical care unit in France
Authors: Deschamps Jack-Yves , Topie Emmanuel , Roux Françoise 
Published: December 2015

Case series summary In October 2011, an abnormally large morbidity and mortality event was noted in the intensive care unit (ICU) of a veterinary school hospital in Nantes, France. Cats, and cats only, transferred from the emergency room presented with fever, ulcers on the tongue and cutaneous lesions around venepuncture or surgical incision sites, leading to suspicion of a feline calicivirus-associated virulent systemic disease confirmed with reverse transcriptase-polymerase chain reaction. A total of 14 cats were suspected. The clinical features and the origin of the contamination were described for each cat. The median length of incubation was 4.5 days. Fifty-seven percent of the cats were euthanased (8/14) and 21% died (3/14), with a combined mortality of 79% (11/14) – the highest ever reported. Median survival was 12 days. The recovery rate was 21% (3/14). Relevance and novel information Eight outbreaks have been reported, in veterinary clinics or in group-housed cats. The main unusual aspects of the present outbreak were: (1) the extreme flare-up of lesions at sites of skin breach, precluding any puncture/incision; (2) the suggested better survival rate at home than in hospital; and (3) the immediate control of the outbreak after recognition of the disease. Other striking but less unusual features of this outbreak were: (4) the increasing of the virulence of the calicivirus with the passage of time; and (5) the primary role that the caregivers’ hands played in the spread of the outbreak.
How I treat extramedullary myeloma
Authors: Touzeau Cyrille , Moreau Philippe 
Published: December 2015

AbstractExtramedullary myeloma (EMM) is defined by the presence of plasma cells (PCs) outside the bone marrow in a patient with multiple myeloma (MM). Using sensitive imaging techniques including magnetic resonance imaging and positron emission tomography/computed tomography, EMM may be found in up to 30% of MM patients across the overall disease course. The molecular mechanisms underlying the hematogenous spread of PCs outside the bone marrow are only partially known and involve hypoxia and an altered expression of adhesion molecules. Extramedullary disease is associated with adverse prognostic factors (ie, high lactate dehydrogenase level, 17p deletion, and high-risk gene expression profile). The prognosis of EMM is poor, and the median overall survival of patients who experience an extramedullary relapse is <6 months. The adverse prognosis is less pronounced in patients with bone-related plasmacytomas than in those with hematogenous EMM. EMM patients should be considered as having high-risk myeloma and treated accordingly. However, EMM clinical situations are extraordinarily heterogeneous, and their management is particularly challenging. In the present review, a case-and-comment format is used to describe our approach to the management of EMM.
Sensitivity of C-Tb: a novel RD-1-specific skin test for the diagnosis of tuberculosis infection
Authors: Hoff Soren T. , Peter Jonathan G. , Theron Grant , Pascoe Mellissa , Tingskov Pernille N. , Aggerbeck Henrik , Kolbus Daniel , Ruhwald Morten , Andersen Peter , Dheda Keertan 
Published: December 2015

C-Tb, a novelMycobacterium tuberculosisand 6-kDa early secretory antigenic target/10-kDa culture filtrate protein (ESAT-6/CFP-10)-specific skin test, has high specificity in bacille Calmette–Guerin-vaccinated healthy controls. However, the sensitivity of C-Tb has hitherto not been determined. The objective was to determine the sensitivity of C-Tb in patients with active tuberculosis (TB) in comparison with the tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube (QFT-GIT).C-Tb and TST were randomly administered in a double-blinded fashion to one or the other forearm in 253 patients with active TB with or without HIV co-infection. QFT-GIT testing was performed prior to skin testing.Using a receiver operating characteristic curve-derived cut-point of 5 mm, C-Tb sensitivity was similar to QFT-GIT (73.9 (95% CI 67.8–79.3)versus75.1 (95% CI 69.3–80.2)), and similar in HIV-infected and HIV-uninfected patients (76.7 (95% CI 69.0–83.3)versus69.5 (95% CI 59.2–78.5)). However, sensitivity was significantly diminished in HIV-infected patients with CD4 counts <100 cells·mm–3. C-Tb and QFT-GIT combined had significantly higher sensitivity than C-Tb alone (p<0.0001). C-Tb was safe with no significant adverse events. The 5 mm cut-point corresponded to that found in the previously published specificity study (TESEC-04).C-Tb has similar sensitivity compared with QFT-GIT for the diagnosis ofM. tuberculosisinfection. Sensitivity was reduced only in HIV-infected patients with severe immunosuppression. Further studies in different settings are required to validate the proposed 5 mm cut-point.
Phylogenomic analyses reveal a molecular signature linked to subterranean adaptation in rodents
Authors: Du Kang , Yang Liandong , He Shunping 
Published: December 2015

AbstractBackgroundGenome-wide signatures of convergent evolution are widely expected but rarely revealed in animals. Subterranean rodent genome and transcriptome data produced by next-generation sequencing facilitate the use of phylogenetic methods to infer non-synonymous and synonymous substitution rates within coding regions, which can reveal changes at the molecular level that are correlated with the dramatic shift from a terrestrial to subterranean habitat.ResultsOur study used previously sequenced genome or transcriptome data of two subterranean rodents, the blind mole rat and naked mole rat, and their terrestrial relatives, the mouse and guinea pig, to investigate the genetic basis of rodent subterranean adaptation. An analysis of 4996 orthologous genes revealed that the substitution pace of coding sequences was significantly slower in the blind mole rat than in the mouse, and slower in the naked mole rat than in the guinea pig. The dN/dS ratio was significantly higher in the blind mole rat than in the mouse and in the naked mole rat than in the guinea pig. These patterns are most likely related to the longer generation time and lower effective population size of subterranean rodents caused by subterranean ecological constraints. We also identified some genes and gene ontology (GO) categories that might be candidates for adaptation to subterranean life.ConclusionsOur study reveals a case of subterranean convergent evolution in rodents that is correlated with change in the pace and mode of molecular evolution observed at the genome scale. We believe that this genomic signature could have also evolved in other cases of subterranean convergence. Additionally, the genes that displayed the most radical changes in their patterns of evolution and their associated GO categories provide a strong basis for further comparative and functional studies, and potentially reveal molecular signatures of adaptation to subterranean life.