bluuebunny/crossref_metadata_2025_split huggingface dataset:
New climatic targets against global warming: will the maximum 2 °C temperature rise affect estuarine benthic communities?
Authors: Crespo Daniel , Grilo Tiago Fernandes , Baptista Joana , Coelho João Pedro , Lillebø Ana Isabel , Cássio Fernanda , Fernandes Isabel , Pascoal Cláudia , Pardal Miguel Ângelo , Dolbeth Marina 
Published: June 2017

AbstractThe Paris Agreement signed by 195 countries in 2015 sets out a global action plan to avoid dangerous climate change by limiting global warming to remain below 2 °C. Under that premise,in situexperiments were run to test the effects of 2 °C temperature increase on the benthic communities in a seagrass bed and adjacent bare sediment, from a temperate European estuary. Temperature was artificially increasedin situand diversity and ecosystem functioning components measured after 10 and 30 days. Despite some warmness effects on the analysed components, significant impacts were not verified on macro and microfauna structure, bioturbation or in the fluxes of nutrients. The effect of site/habitat seemed more important than the effects of the warmness, with the seagrass habitat providing more homogenous results and being less impacted by warmness than the adjacent bare sediment. The results reinforce that most ecological responses to global changes are context dependent and that ecosystem stability depends not only on biological diversity but also on the availability of different habitats and niches, highlighting the role of coastal wetlands. In the context of the Paris Agreement it seems that estuarine benthic ecosystems will be able to cope if global warming remains below 2 °C.
Preparation and Properties of A Hyperbranch-Structured Polyamine adsorbent for Carbon Dioxide Capture
Authors: He Hui , Hu Yajie , Chen Shuixia , Zhuang Linzhou , Ma Beibei , Wu Qinghua 
Published: June 2017

AbstractA fibrous adsorbent with amino-terminated hyperbranch structure (PP-AM-HBP-NH2) was prepared by grafting hyperbranched polyamine (HBP-NH2) onto the acrylamide-modified polypropylene (PP) fibers. The grafting of AM on PP fibers provided the active sites for introducing HBP-NH2 onto the PP fibers. This kind of “grafting to” procedure to synthesize hyperbranch-structured fiber could overcome the disadvantages of stepwise growth procedure, avoiding the complicated synthesis process and the requirement of strict experimental conditions. The grafted HBP-NH2 was three-dimensional dentritic architecture and had a large number of pores existing within the grafted polymers, which is favorable for CO2 molecules to diffuse into the HBP-NH2. Therefore, the as-prepared PP-AM-HBP-NH2 fibers showed a high adsorption capacity (5.64 mmol/g) for CO2 in the presence of water at 25 °C, and the utilization efficiency of alkyl amino groups could reach 88.2%, demonstrating that the hyperbranched structure of adsorbents can greatly promote adsorption capacity and efficiency. This could be attributed to better swelling properties and lower mass transfer resistance to CO2 of the hyperbranched adsorbent. PP-AM-HBP-NH2 also showed excellent regeneration performance, and it could maintain the same adsorption capacity for CO2 after 15 recycle numbers as the fresh adsorbent.
Vertical and bevel-structured SiC etching techniques incorporating different gas mixture plasmas for various microelectronic applications
Authors: Sung Ho-Kun , Qiang Tian , Yao Zhao , Li Yang , Wu Qun , Lee Hee-Kwan , Park Bum-Doo , Lim Woong-Sun , Park Kyung-Ho , Wang Cong 
Published: June 2017

AbstractThis study presents a detailed fabrication method, together with validation, discussion, and analysis, for state-of-the-art silicon carbide (SiC) etching of vertical and bevelled structures by using inductively coupled plasma reactive ion etching (ICP-RIE) for microelectronic applications. Applying different gas mixtures, a maximum bevel angle of 87° (almost vertical), large-angle bevels ranging from 40° to 80°, and small-angel bevels ranging from 7° to 17° were achieved separately using distinct gas mixtures at different ratios. We found that SF6 with additive O2 was effective for vertical etching, with a best etching rate of 3050 Å/min. As for the large-angle bevel structures, BCl3 + N2 gas mixtures show better characteristics, exhibiting a controllable and large etching angle range from 40° to 80° through the adjustment of the mixture ratio. Additionally, a Cl2 + O2 mixture at different ratios is applied to achieve a small-angel bevels ranging from 7° to 17°. A minimum bevel angel of approximately 7° was achieved under the specific volume of 2.4 sccm Cl2 and 3.6 sccm O2. These results can be used to improve performance in various microelectronic applications including MMIC via holes, PIN diodes, Schottky diodes, JFETs’ bevel mesa, and avalanche photodiode fabrication.
A Music-Related Quality of Life Measure to Guide Music Rehabilitation for Adult Cochlear Implant Users
Authors: Dritsakis Giorgos , van Besouw Rachel M. , Kitterick Pádraig , Verschuur Carl A. 
Published: June 2017

PurposeA music-related quality of life (MuRQoL) questionnaire was developed for the evaluation of music rehabilitation for adult cochlear implant (CI) users. The present studies were aimed at refinement and validation.MethodTwenty-four experts reviewed the MuRQoL items for face validity. A refined version was completed by 147 adult CI users, and psychometric techniques were used for item selection, assessment of reliability, and definition of the factor structure. The same participants completed the Short Form Health Survey for construct validation. MuRQoL responses from 68 CI users were compared with those of a matched group of adults with normal hearing.ResultsEighteen items measuring music perception and engagement and 18 items measuring their importance were selected; they grouped together into 2 domains. The final questionnaire has high internal consistency and repeatability. Significant differences between CI users and adults with normal hearing and a correlation between music engagement and quality of life support construct validity. Scores of music perception and engagement and importance for the 18 items can be combined to assess the impact of music on the quality of life.ConclusionThe MuRQoL questionnaire is a reliable and valid measure of self-reported music perception, engagement, and their importance for adult CI users with potential to guide music aural rehabilitation.
Identification of Swallowing Tasks From a Modified Barium Swallow Study That Optimize the Detection of Physiological Impairment
Authors: Jordan Hazelwood R. , Armeson Kent E. , Hill Elizabeth G. , Bonilha Heather Shaw , Martin-Harris Bonnie 
Published: June 2017

Purpose
The purpose of this study was to identify which swallowing task(s) yielded the worst performance during a standardized modified barium swallow study (MBSS) in order to optimize the detection of swallowing impairment.

Method
This secondary data analysis of adult MBSSs estimated the probability of each swallowing task yielding the derived Modified Barium Swallow Impairment Profile (MBSImP™©; Martin-Harris et al., 2008) Overall Impression (OI; worst) scores using generalized estimating equations. The range of probabilities across swallowing tasks was calculated to discern which swallowing task(s) yielded the worst performance.

Results
Large-volume, thin-liquid swallowing tasks had the highest probabilities of yielding the OI scores for oral containment and airway protection. The cookie swallowing task was most likely to yield OI scores for oral clearance. Several swallowing tasks had nearly equal probabilities (≤ .20) of yielding the OI score.

Conclusions
The MBSS must represent impairment while requiring boluses that challenge the swallowing system. No single swallowing task had a sufficiently high probability to yield the identification of the worst score for each physiological component. Omission of swallowing tasks will likely fail to capture the most severe impairment for physiological components critical for safe and efficient swallowing. Results provide further support for standardized, well-tested protocols during MBSS.
Flexible and stretchable 3D printed passive UHF RFID tag
Authors: Rizwan M. , Khan M.W.A. , He H. , Virkki J. , Sydänheimo L. , Ukkonen L. 
Published: June 2017

The fabrication and analysis of a flexible and stretchable 3D printed passive ultra‐high frequency (UHF) radio‐frequency identification (RFID) tag are presented. The tag is fabricated on a flexible 3D printed Ninjaflex substrate and the conductive part of the tag consists of stretchable silver conductive paste dispensed with direct write method. The details of the 3D printing of the substrate, the characterisation of the substrate material at the UHF band, the direct write dispensing of the tag antenna, and the simulation and wireless measurement results of the fabricated tag are outlined. Moreover, to verify the flexibility and stretchability of the tag, strain reliability results of the tag are presented. Measurement results show that initially the manufactured tag achieves a 10.6 m read range. After 100 times of harsh stretching, the read range is still 7.4 m. Overall, the performance of the tag is robust and concludes that the fabrication methodology can be used in the manufacturing of RFID tags for future identification and sensing applications.
Kleinhirninfarkt nach CO-Intoxikation und hyperbarer Sauerstofftherapie
Authors: Wick Matthias , Schneiker André , Bele Sylvia , Pawlik Michael , Meyringer Helmut , Graf Bernhard , Wendl Christina , Kieninger Martin 
Published: June 2017

ZusammenfassungEs wird von einem Patienten berichtet, der nach einem Suizidversuch mittels Kohlenmonoxidintoxikation einen raumfordernden Kleinhirninfarkt und konsekutiven okklusiven Hydrozephalus entwickelte. Durch das rechtzeitige Detektieren der intrazerebralen Läsion konnte ein Überleben des Patienten ohne schwerwiegendes neurologisches Defizit ermöglicht werden.
Welche Rolle spielt die Immunonkologie beim Urothelkarzinom aus pathologischer Sicht?
Authors: Erlmeier Franziska , Steffens Sandra , Hartmann Arndt 
Published: June 2017

ZusammenfassungImmuntherapeutika, wie beispielsweise die Programmed death 1-(PD-1-)Antikörper Pembrolizumab und Nivolumab, sind bei mehreren Tumorentitäten, wie z. B. dem malignen Melanom, in Europa bereits in der Erstlinientherapie zugelassen. Nach dem durchschlagenden Erfolg dieser Antikörper bei zahlreichen Tumorarten wird nun auch der mögliche Einsatz in der Uroonkologie erforscht. Die Zulassung des PD-1-Antikörpers Nivolumab für die Therapie des metastasierten Nierenzellkarzinoms setzte in der Uroonkologie einen neuen Meilenstein. Im Mai 2016 wurde dieser Erfolg durch die Zulassung des Programmed death ligand 1 (PD-L1)-Antikörpers Atezolizumab beim fortgeschrittenen Urothelkarzinom fortgeführt. Außerdem laufen derzeit zahlreiche klinische Studien mit anderen Checkpoint-Inhibitoren, welche ebenfalls eine vielversprechende Wirksamkeit beim fortgeschrittenen Urothelkarzinom zeigen.Die Grundlage für den Einsatz dieser Immuntherapeutika bildet unter anderem die immunhistochemische Auswertung des Tumors durch den Pathologen. Um eine einheitliche pathologische Bewertung zu erzielen, besteht aktuell jedoch noch ein erheblicher Standardisierungsbedarf. Bis dato werden sowohl unterschiedliche Bewertungssysteme als auch unterschiedliche Detektionssysteme für ein und denselben Antikörper angewandt. Dadurch wird die Vergleichbarkeit der Studien und damit die Beurteilung der Wirksamkeit der jeweiligen Antikörper erschwert.
Ischemic Preconditioning and Acute Recovery of Performance in Rugby Union Players
Authors: Garcia Cintia , da Mota Gustavo , Leicht Anthony , Marocolo Moacir 
Published: June 2017

AbstractIschemic preconditioning has been used as a training and/or pre-competition strategy; however its use for post-exercise recovery is still unclear. This study aimed to evaluate the impact of ischemic preconditioning on performance and recovery ratings following a simulated match in sub-elite rugby players. Following baseline measures, male players (n=8) performed a 40 min, rugby-specific exercise protocol followed by an intervention: 21 min of ischemic preconditioning (3×5 min occlusion at 220 mmHg with 2 min reperfusion at 0 mmHg) or passive rest (control) on 2 separate days. An agility T-test, a single vertical countermovement jump and 30 s of continuous vertical jumps were performed at baseline (–24 h), immediately after exercise, and immediately after the intervention. The rugby-specific exercise protocol induced similar mean heart rates (158.3±18.0 vs. 158.7±16.0 bpm) and perceived exertion levels (8.2±0.9 vs. 8.0±1.0) for both trials with all recovery performance measures and rating of recovery (13.9±1.4 vs. 13.6±1.6) similar between ischemic preconditioning and control trials (best p=0.385). We conclude that the use of ischemic preconditioning does not improve recovery acutely (~1 h) including specific variables related to rugby performance in amateur rugby union players.
Micronutrient Supplementation does not Change Complement System Response to Heavy Training
Authors: Santos José , Zacca Rodrigo , Fernandes Ricardo 
Published: June 2017

AbstractWe aimed to examine the micronutrient supplementation effect on complement system activity after heavy training. 24 male firefighters were randomly divided into supplemented and placebo groups, and tested for immunology-related parameters using venous blood samples in the fasting state pre- and post-5 weeks of nutritional supplementation. C3 and C4 complement components were determined in a nephelometer from immune complexes formed through specific human antisera and total haemolytic complement activity (CH100) was determined by enzyme immunoassay. Differences between pre- and post-supplementation were observed only for CH100 on placebo group (p=0.004; mean diff −26.92; 95%CI −43.58 to −10.25) and no interaction, treatment or time effects were observed for C3 and C4. Although interaction accounted for 8.8% of the total variance in CH100 (with time effect pre- vs post-accounting for 19.5% of the total variance), the treatment effect (supplemented vs placebo) was not significant. The absence of effects on the complement system response to supplementation during heavy training could be justified by the fact that: (i) nutritional supplements do not improve humoral innate immunity in well-fed subjects; (ii) selected supplements unlikely improve the innate immune system in situations of adequate nutritional status; and/or (iii) selected doses of supplementation were not sufficient to elicit immune changes.
Interplay between tolerance mechanisms to copper and acid stress inEscherichia coli
Authors: Djoko Karrera Y. , Phan Minh-Duy , Peters Kate M. , Walker Mark J. , Schembri Mark A. , McEwan Alastair G. 
Published: June 2017

SignificanceCopper (Cu) is an essential trace metal nutrient in health and is increasingly recognized for its role in the control of infection. The pathogenEscherichia coliencounters host niches with mild to high acidity and elevated copper levels. Our study shows that this bacterium can alter its metabolism and harness the amino acid glutamine to suppress the effects of acid stress and copper toxicity. Given the abundance of glutamine in systemic circulation and its importance in the host immune system, our work provides a new insight into the ways in which bacterial pathogens can adapt and survive host-imposed antibacterial strategies.
Immunoengineering nerve repair
Authors: Mokarram Nassir , Dymanus Kyle , Srinivasan Akhil , Lyon Johnathan G. , Tipton John , Chu Jason , English Arthur W. , Bellamkonda Ravi V. 
Published: June 2017

SignificanceAnnually, more than 250,000 Americans suffer from a peripheral nerve injury, which results in a loss of function and a compromised quality of life. The current clinical gold standard to bridge long, nonhealing nerve gaps, the autograft, has several drawbacks. Therefore, there is a clear and urgent unmet clinical need for an alternative approach that can match or exceed autograft performance. Here we investigated the regenerative effect of fractalkine, a chemokine that preferentially recruits reparative monocytes in the synthetic nerve conduit. Our method of bridging gaps enhanced axonal regeneration and muscle reinnervation and showed results comparable to those observed in autografts.
Population Structure of Digestive Trypsin Phenotypes in Hatcheries for Pacific White Shrimp and Their Frequencies during Growth in Commercial Culture
Authors: Aguiñaga-Cruz Jazmin Asusena , Sainz-Hernández Juan Carlos , González-Prieto Juan Manuel , Vargas-Albores Francisco , Sandoval-Castro Eduardo , Rúbio-Gastelum Damaris , Apún-Molina Juan Pablo , García-Gutiérrez Cipriano 
Published: June 2017

Abstract
Trypsin from Pacific white shrimp Litopenaeus vannamei is a polymorphic protein composed of three alleles (A, B, and C). The C allele is monomorphic for the first region, while A and B are allelic variations for the second region that are segregated according to Mendelian rules. These three alleles give rise to three individual trypsin phenotypes displayed in sodium dodecyl sulfate polyacrylamide gel electrophoresis: CBA, CB, and CA. The expected frequencies from mating CBA males and females resulted in offspring that consisted of 25% CB, 25% CA, and 50% CBA trypsin phenotypes. To define a management protocol for studying shrimp performance associated with the trypsin phenotype, the goal of this study was to determine if the expected proportions of the three trypsin phenotypes are represented in the population structure at breeding age in 11 hatcheries. Here, we hypothesized that the population structure of the trypsin phenotypes is represented by frequencies that are subject to selection, and it is possible to establish a management protocol to study shrimp performance. A total of 2,828 breeding shrimp from 11 hatcheries were analyzed to describe their population structure. The results showed a high frequency of CBA breeders and a near absence of the CA phenotype in the population structure. To discard the possibility that man-made selection is the cause of the trypsin phenotype frequency, the offspring of CBA breeders were cultured in nine commercial ponds, and the phenotype frequencies were monitored during 75 d. Interestingly, the CA phenotype was only present during the early stages of culture, which suggests that the population structure is not due to human selection of CBA shrimp in the hatcheries. In this condition, poslarvae production could be directed to make trials that contribute to describe the difference between the culture performance between phenotypes, but not to support the commercial production of larvae with the highest culture performance trypsin phenotype.
Vaccines Throughout the Lifecycle
Authors: Tan Tina Q. , Flaherty John P. , Gerbie Melvin V. 
Published: June 2017

Abstract
Immunization schedules for infants, children, adolescents, and adults help clinicians ensure that they are administering vaccines in a timely and appropriate manner. Specific, current CDC schedules for infants, children, adolescents, and adults are presented Special attention is paid to recommendations and contraindications for the vaccination of pregnant women and women who are trying to conceive. Details for the specific illnesses, their influences on the pregnant woman and the fetus, vaccination recommendations in the pre-pregnancy, various trimesters, and post-partum periods are given. Safety concerns and Frequently Asked Questions are given significant space as patients and their families are appropriately concerned. Health Care Professionals and their staff needs are included in the recommendations.
Models of Care for Patients With HIV
Authors: Bourgeois James , Cohen Mary Ann , Grimaldi John , Levenson Jon A. , Moghimi Yavar , Fisher Weston , Tran David 
Published: June 2017

Abstract
Numerous contemporary clinical models for the delivery and coordination of psychiatric and other mental health care for patients with HIV within outpatient medical care settings are described in this chapter. Care for patients’ multimorbid psychiatric illness in the context of general medical care for HIV-associated conditions is a pragmatic application of the Engel biopsychosocial model and offers the opportunity for interprofessional collegiality and collaborative care in managing the clinical illnesses and other challenges faced by persons with HIV. The functional descriptions of the various care delivery models include the strengths and challenges faced in operating within these models. Detailed discussions of well-established HIV care delivery models in Boston, New York, and San Francisco are included to illustrate how to tailor the integration of psychiatric services in various institutional settings.
Psychotic Disorders and Serious Mental Illness
Authors: Thompson Alexander , Williams Daniel , Freudenreich Oliver , Angelino Andrew , Treisman Glenn 
Published: June 2017

Abstract
The major public health problem that is HIV/AIDS in persons with a serious mental illness is aptly described a “syndemic.” Having HIV/AIDS puts one at much greater risk for developing a serious mental illness. Conversely, having a serious mental illness, such as schizophrenia, bipolar disorder, major depressive disorder, substance use disorder, is associated with many factors that place one at greater risk for contracting and transmitting HIV. And, in both cases of serious mental illness and HIV/AIDS, each disorder creates many new challenges in the management of the other disorder. This chapter addresses these challenges, which center around being able to participate actively and adhere to medication regimens needed to manage both medical and psychiatric conditions. Fortunately, specialized models of care like comprehensive, integrated clinics and nurse care managers are ways to provide effective, satisfying, and cost-effective care to this most vulnerable population.
Psychoneuroimmunology and HIV
Authors: Carrico Adam W. , Antoni Michael H. 
Published: June 2017

Abstract
Psychoneuroimmunology (PNI) examines the biological and behavioral pathways whereby psychosocial factors may influence the course of chronic medical conditions, including HIV/AIDS. This chapter summarizes PNI research conducted examining the possible role of negative life events (including bereavement), stress reactivity, personality factors, cognitive appraisals, and affective states (depression) in HIV illness progression. Because much of this research was conducted in the era prior to the advent of effective antiretroviral therapy, important questions remain regarding whether there the associations of psychosocial factors with HIV illness progression are independent of medication adherence and persistence. There is also increasing recognition that chronic viral infections such as HIV have neuropsychiatric effects, and more recent PNI research has focused on studying the bidirectional communication between the immune system and central nervous system in HIV. Future research should focus on obtaining definitive answers to these questions to inform the development of novel approaches for reducing psychiatric symptoms and optimizing health outcomes among persons with HIV.