bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time, perspective and semantic representation
Authors: JASZCZOLT K. M. 
Published: May 2017

abstractI discuss the perspectival nature of temporality in discourse and argue that the human concept of time can no more be dissociated from the perspectival thought than the concept of the self can. The corollary of this observation is that perspectival temporality can no more be excluded from the semantic representation than the notion of the self can: neither can be reduced to the bare referent for the purpose of semantic representation if the latter is to retain cognitive plausibility. I present such a semanticquaconceptual approach to temporal reference developed within my theory of Default Semantics. I build upon my theory of time as epistemic modality according to which, on the level of conceptualquasemantic building blocks, temporality reduces to degrees of detachment from the certainty of thehereand thenow. I also address the questions of temporal asymmetry between the past and the future, and the relation between metaphysical time (timeM), psychological time (timeE, where ‘E’ marks the domain of epistemological enquiry), and time in natural language (timeL), concluding that the perspective-infused timeEand timeLare compatible with timeMof mathematical models of spacetime: all are definable through possibility and perspectivity.
ORNAMENT AND DISTRACTION: PERIPHERAL AESTHETICS IN THE NINETEENTH CENTURY
Authors: Chapman Alison Georgina 
Published: May 2017

In the section devoted to “Attention”inThe Principles of Psychology(1890), William James describes how the “‘adaptation of the attention’” can alter our perception of an image so as to permit multiple visual formulations (417). In his example of a two-dimensional drawing of a cube, we can see the three-dimensional body only once our attention has been primed by “preperception”: the image formed by the combination of lines has “no connection with what the picture ostensibly represents” (419, 418). In a footnote to this passage, however, James uses an example from Hermann Lotze'sMedicinische Psychologie(1852), to show how a related phenomenon can occur involuntarily, and in states of distraction rather than attention:In quietly lying and contemplating a wall-paper pattern, sometimes it is the ground, sometimes the design, which is clearer and consequently comes nearer. . .all without any intention on our part. . . .Often it happens in reverie that when we stare at a picture, suddenly some of its features will be lit up with especial clearness, although neither its optical character nor its meaning discloses any motive for such an arousal of the attention. (419)James uses the formal illogicality of the wallpaper (its lack of compositional center prevents it from dictating the trajectory for our attention according to intrinsic aesthetic laws) to demonstrate the volatility of our ideational centers, particularly in moments of reverie or inattention. Without the intervention of the will, James says, our cognitive faculties are always in undirected motion, which occurs below the strata of our mental apprehension. Momentary instances of focus or attunement are generated only by the imperceptible and purely random “irradiations of brain-tracts” (420). Attention, for James, is the artistic power of the mind; it applies “emphasis,” “intelligible perspective,” and “clear and vivid form” to the objects apprehended by the faculties of perception, it “makesexperience more than it is made by it” (381). Reverie, a moment when attention has been reduced to a minimum, thus demands an alternative aesthetic analog, where composition is reduced to a minimum too.
VALENTINES AND THE VICTORIAN IMAGINATION:MARY BARTONANDFAR FROM THE MADDING CROWD
Authors: Koehler Karin 
Published: May 2017

The custom of celebrating Valentine'sDay dates back to the Middle Ages. The emergence of Valentine's Day as a commercial holiday, exploited above all by the greeting card industry, is more recent. In Britain, Valentine's Day cards emerged in the eighteenth century. As David Vincent writes,The observance of 14 February underwent a metamorphosis during the eighteenth century which was later to befall many other customs. What had begun as an exchange of gifts, with many local variations of obscure origin, was gradually transformed into an exchange of tokens and letters, which in turn began to be replaced by printed messages from the end of the century. (44)Early examples of pre-printed Valentine's Day stationery and manuals for the composition of the perfect valentine reveal that existing folk customs were swiftly adapted by modern print culture and an increasingly literate population. However, it was the 1840 introduction of Rowland Hill's penny post in Britain, alongside concomitant advances in American and European postal infrastructure, which led to a veritable explosion in the exchange of valentines, moulding the practice into a shape still recognisable today (see Golden 222). Hill not only democratised access to written communication by lowering prices, he also anonymised epistolary exchange. Prepaid stamps and pillar post boxes made it possible to correspond with anyone, anywhere, without giving away one's identity. And while sending an anonymous letter would have been perceived as a violation of epistolary decorum during the remainder of the year, on Valentine's Day it was not only acceptable but, as Farmer Boldwood hints in Thomas Hardy'sFar from the Madding Crowd(1874), expected. The opportunity for anonymous correspondence generated an enthusiastic response.
The Limits of Kant’s Cosmopolitanism: Theory, Practice, and the Crisis in Syria
Authors: Altman Matthew C. 
Published: May 2017

AbstractAlthough Kant defends a cosmopolitan ideal, his philosophy is problematically vague regarding how to achieve it, which lends support to the empty formalism charge. How Kant would respond to the crisis in Syria reveals that judgement plays too central a role, because Kantian principles lead to equally reasonable but opposite conclusions on how to weigh the duty of hospitality to refugees against a state’s duty to its own citizens, the right of prevention towards ISIS against the duty not to harm non-combatants, and the responsibility to protect the people of Syria against the duty of non-interference in its internal affairs.
Wide-field three-photon excitation in biological samples
Authors: Rowlands Christopher J , Park Demian , Bruns Oliver T , Piatkevich Kiryl D , Fukumura Dai , Jain Rakesh K , Bawendi Moungi G , Boyden Edward S , So Peter TC 
Published: May 2017

AbstractThree-photon wide-field depth-resolved excitation is used to overcome some of the limitations in conventional point-scanning two- and three-photon microscopy. Excitation of chromophores as diverse as channelrhodopsins and quantum dots is shown, and a penetration depth of more than 700 μm into fixed scattering brain tissue is achieved, approximately twice as deep as that achieved using two-photon wide-field excitation. Compatibility with live animal experiments is confirmed by imaging the cerebral vasculature of an anesthetized mouse; a complete focal stack was obtained without any evidence of photodamage. As an additional validation of the utility of wide-field three-photon excitation, functional excitation is demonstrated by performing three-photon optogenetic stimulation of cultured mouse hippocampal neurons expressing a channelrhodopsin; action potentials could reliably be excited without causing photodamage.
Wide bandgap BaSnO3 films with room temperature conductivity exceeding 104 S cm−1
Authors: Prakash Abhinav , Xu Peng , Faghaninia Alireza , Shukla Sudhanshu , Ager Joel W. , Lo Cynthia S. , Jalan Bharat 
Published: May 2017

AbstractWide bandgap perovskite oxides with high room temperature conductivities and structural compatibility with a diverse family of organic/inorganic perovskite materials are of significant interest as transparent conductors and as active components in power electronics. Such materials must also possess high room temperature mobility to minimize power consumption and to enable high-frequency applications. Here, we report n-type BaSnO3 films grown using hybrid molecular beam epitaxy with room temperature conductivity exceeding 104 S cm−1. Significantly, these films show room temperature mobilities up to 120 cm2 V−1 s−1 even at carrier concentrations above 3 × 1020 cm−3 together with a wide bandgap (3 eV). We examine the mobility-limiting scattering mechanisms by calculating temperature-dependent mobility, and Seebeck coefficient using the Boltzmann transport framework and ab-initio calculations. These results place perovskite oxide semiconductors for the first time on par with the highly successful III–N system, thereby bringing all-transparent, high-power oxide electronics operating at room temperature a step closer to reality.
Hallmarks of Hunds coupling in the Mott insulator Ca2RuO4
Authors: Sutter D. , Fatuzzo C. G. , Moser S. , Kim M. , Fittipaldi R. , Vecchione A. , Granata V. , Sassa Y. , Cossalter F. , Gatti G. , Grioni M. , Rønnow H. M. , Plumb N. C. , Matt C. E. , Shi M. , Hoesch M. , Kim T. K. , Chang T-R , Jeng H-T , Jozwiak C. , Bostwick A. , Rotenberg E. , Georges A. , Neupert T. , Chang J. 
Published: May 2017

AbstractA paradigmatic case of multi-band Mott physics including spin-orbit and Hund’s coupling is realized in Ca2RuO4. Progress in understanding the nature of this Mott insulating phase has been impeded by the lack of knowledge about the low-energy electronic structure. Here we provide—using angle-resolved photoemission electron spectroscopy—the band structure of the paramagnetic insulating phase of Ca2RuO4 and show how it features several distinct energy scales. Comparison to a simple analysis of atomic multiplets provides a quantitative estimate of the Hund’s coupling J=0.4 eV. Furthermore, the experimental spectra are in good agreement with electronic structure calculations performed with Dynamical Mean-Field Theory. The crystal field stabilization of the dxy orbital due to c-axis contraction is shown to be essential to explain the insulating phase. These results underscore the importance of multi-band physics, Coulomb interaction and Hund’s coupling that together generate the Mott insulating state of Ca2RuO4.
Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1
Authors: Morris Edward J. , Kawamura Eiko , Gillespie Jordan A. , Balgi Aruna , Kannan Nagarajan , Muller William J. , Roberge Michel , Dedhar Shoukat 
Published: May 2017

AbstractCancer cells frequently have amplified centrosomes that must be clustered together to form a bipolar mitotic spindle, and targeting centrosome clustering is considered a promising therapeutic strategy. A high-content chemical screen for inhibitors of centrosome clustering identified Stattic, a Stat3 inhibitor. Stat3 depletion and inhibition in cancer cell lines and in tumours in vivo caused significant inhibition of centrosome clustering and viability. Here we describe a transcription-independent mechanism for Stat3-mediated centrosome clustering that involves Stathmin, a Stat3 interactor involved in microtubule depolymerization, and the mitotic kinase PLK1. Furthermore, PLK4-driven centrosome amplified breast tumour cells are highly sensitive to Stat3 inhibitors. We have identified an unexpected role of Stat3 in the regulation of centrosome clustering, and this role of Stat3 may be critical in identifying tumours that are sensitive to Stat3 inhibitors.
The S. aureus 4-oxalocrotonate tautomerase SAR1376 enhances immune responses when fused to several antigens
Authors: Diemen Pauline M. van , Leneghan Darren B. , Brian Iona J. , Miura Kazutoyo , Long Carole A. , Milicic Anita , Biswas Sumi , Rollier Christine S. , Wyllie David H. 
Published: May 2017

AbstractA persistent goal of vaccine development is the enhancement of the immunogenicity of antigens while maintaining safety. One strategy involves alteration of the presentation of the antigen by combining antigens with a multimeric scaffold. Multi-antigen vaccines are under development, and there are presently far more candidate antigens than antigen scaffolding strategies. This is potentially problematic, since prior immunity to a scaffold may inhibit immune responses to the antigen-scaffold combination. In this study, a series of domains from S. aureus which have been shown to crystallise into multimeric structures have been examined for their scaffolding potential. Of these domains, SAR1376, a 62 amino acid member of the 4-oxalocrotonate tautomerase (4-OT) family, was pro-immunogenic in mice when fused to a range of pathogen antigens from both S. aureus and P. falciparum, and delivered by either DNA vaccination, viral vector vaccines or as protein-in-adjuvant formulations. The adjuvant effect did not depend on enzymatic activity, but was abrogated by mutations disrupting the hexameric structure of the protein. We therefore propose that SAR1376, and perhaps other members of the 4-OT protein family, represent very small domains which can be fused to a wide range of antigens, enhancing immune responses against them.
The Guanacaste Volcanic Arc Sliver of Northwestern Costa Rica
Authors: Montero Walter , Lewis Jonathan C. , Araya Maria Cristina 
Published: May 2017

AbstractRecent studies have shown that the Nicoya Peninsula of northwestern Costa Rica is moving northwestward ~11 mm a−1 as part of a tectonic sliver. Toward the northwest in El Salvador the northern sliver boundary is marked by a dextral strike-slip fault system active since Late Pleistocene time. To the southeast there is no consensus on what constitutes the northern boundary of the sliver, although a system of active crustal faults has been described in central Costa Rica. Here we propose that the Haciendas-Chiripa fault system serves as the northeastern boundary for the sliver and that the sliver includes most of the Guanacaste volcanic arc, herein the Guanacaste Volcanic Arc Sliver. In this paper we provide constraints on the geometry and kinematics of the boundary of the Guanacaste Volcanic Arc Sliver that are timely and essential to any models aimed at resolving the driving mechanism for sliver motion. Our results are also critical for assessing geological hazards in northwestern Costa Rica.
Intelligibility of locally time-reversed speech: A multilingual comparison
Authors: Ueda Kazuo , Nakajima Yoshitaka , Ellermeier Wolfgang , Kattner Florian 
Published: May 2017

AbstractA set of experiments was performed to make a cross-language comparison of intelligibility of locally time-reversed speech, employing a total of 117 native listeners of English, German, Japanese, and Mandarin Chinese. The experiments enabled to examine whether the languages of three types of timing—stress-, syllable-, and mora-timed languages—exhibit different trends in intelligibility, depending on the duration of the segments that were temporally reversed. The results showed a strikingly similar trend across languages, especially when the time axis of segment duration was normalised with respect to the deviation of a talker’s speech rate from the average in each language. This similarity is somewhat surprising given the systematic differences in vocalic proportions characterising the languages studied which had been shown in previous research and were largely replicated with the present speech material. These findings suggest that a universal temporal window shorter than 20–40 ms plays a crucial role in perceiving locally time-reversed speech by working as a buffer in which temporal reorganisation can take place with regard to lexical and semantic processing.
Band Gap Engineering of Multi-Junction Solar Cells: Effects of Series Resistances and Solar Concentration
Authors: Zeitouny Joya , Katz Eugene A. , Dollet Alain , Vossier Alexis 
Published: May 2017

AbstractMulti-junction (MJ) solar cells are one of the most promising technologies achieving high sunlight to electricity conversion efficiency. Resistive losses constitute one of the main underlying mechanisms limiting their efficiency under high illumination. In this paper, we study, by numerical modeling, the extent to which a fine-tuning of the different electronic gaps involved in MJ stacks may mitigate the detrimental effects of series resistance losses for concentration-dependent and independent series resistances. Our results demonstrate that appropriate bandgap engineering may lead to significantly higher conversion efficiency at illumination levels above ~1000 suns and series resistance values typically exceeding 0.02 Ω cm2, due to lower operating current and, in turn, series resistance losses. The implications for future generations of solar cells aiming at an improved conversion of the solar spectrum are also addressed.
Adsorption energy of oxygen molecules on graphene and two-dimensional tungsten disulfide
Authors: Bagsican Filchito Renee , Winchester Andrew , Ghosh Sujoy , Zhang Xiang , Ma Lulu , Wang Minjie , Murakami Hironaru , Talapatra Saikat , Vajtai Robert , Ajayan Pulickel M. , Kono Junichiro , Tonouchi Masayoshi , Kawayama Iwao 
Published: May 2017

AbstractAdsorption of gas molecules on the surface of atomically layered two-dimensional (2D) materials, including graphene and transition metal dichalcogenides, can significantly affect their electrical and optical properties. Therefore, a microscopic and quantitative understanding of the mechanism and dynamics of molecular adsorption and desorption has to be achieved in order to advance device applications based on these materials. However, recent theoretical calculations have yielded contradictory results, particularly on the magnitude of the adsorption energy. Here, we have experimentally determined the adsorption energy of oxygen molecules on graphene and 2D tungsten disulfide using temperature-programmed terahertz (THz) emission microscopy (TPTEM). The temperature dependence of THz emission from InP surfaces covered with 2D materials reflects the change in oxygen concentration due to thermal desorption, which we used to estimate the adsorption energy of oxygen molecules on graphene (~0.15 eV) and tungsten disulphide (~0.24 eV). Furthermore, we used TPTEM to visualize relative changes in the spatial distribution of oxygen molecules on monolayer graphene during adsorption and desorption. Our results provide much insight into the mechanism of molecular adsorption on the surface of 2D materials, while introducing TPTEM as a novel and powerful tool for molecular surface science.
Impacts of carbon nanomaterials on the diversity of microarthropods in turfgrass soil
Authors: Bai Xue , Zhao Shulan , Duo Lian 
Published: May 2017

AbstractNanoscale materials have been produced with unprecedented speed due to their widespread use, and they may eventually be released into the environment. As effective adsorbents for heavy metals, carbon nanomaterials can be used to immobilize metals in contaminated soil, but little information is available regarding their effects on soil microarthropods. This study was designed to investigate the influence of three types of carbon nanomaterials, graphene (G), graphene oxide (GO) and carbon nanotubes (CNTs) on soil microarthropod communities under turfgrass growth conditions. The application of carbon nanomaterials resulted in increased abundance of all soil microarthropods, especially in the GO and CNT treatments. GO also significantly increased the abundances of multiple trophic functional groups, including predators, detritivores, herbivores and fungivores. Further, the dominant genera varied among the treatments. Herbivorous microarthropods predominated in the control, whereas predatory species predominated in the carbon nanomaterial treatments. Carbon nanomaterials also increased the total taxonomic richness, Shannon diversity index, and dominance index of the microarthropod community, but they decreased the evenness index. Higher diversity of soil microarthropods indicates an environment suitable for soil mesofauna and for enhanced decomposition and nutrient cycling in the soil food web.
“TORNADO” – Theranostic One-Step RNA Detector; microfluidic disc for the direct detection of microRNA-134 in plasma and cerebrospinal fluid
Authors: McArdle Hazel , Jimenez-Mateos Eva M. , Raoof Rana , Carthy Eadaoin , Boyle David , ElNaggar Hany , Delanty Norman , Hamer Hajo , Dogan Muejgdan , Huchtemann Tessa , Kӧrtvelyessy Peter , Rosenow Felix , Forster Robert J. , Henshall David C. , Spain Elaine 
Published: May 2017

AbstractDiagnosis of seizure disorders such as epilepsy currently relies on clinical examination and electroencephalogram recordings and is associated with substantial mis-diagnosis. The miRNA, miR-134 (MIR134 in humans), has been found to be elevated in brain tissue after experimental status epilepticus and in human epilepsy cells and their detection in biofluids may serve as unique biomarkers. miRNAs from unprocessed human plasma and human cerebrospinal fluid samples were used in a novel electrochemical detection based on electrocatalytic platinum nanoparticles inside a centrifugal microfluidic device where the sandwich assay is formed using an event triggered release system, suitable for the rapid point-of-care detection of low abundance biomarkers of disease. The device has the advantage of controlling the rotation speed of the centrifugal device to pump nanoliter volumes of fluid at a set time and manipulate the transfer of liquids within the device. The centrifugal platform improves reaction rates and yields by proposing efficient mixing strategies to overcome diffusion-limited processes and improve mass transport rates, resulting in reduced hybridization times with a limit of detection of 1 pM target concentration. Plasma and cerebrospinal fluid samples (unprocessed) from patients with epilepsy or who experienced status epilepticus were tested and the catalytic response obtained was in range of the calibration plot. This study demonstrates a rapid and simple detection for epilepsy biomarkers in biofluid.
Microfluidic system for monitoring temporal variations of hemorheological properties and platelet adhesion in LPS-injected rats
Authors: Yeom Eunseop , Kim Hye Mi , Park Jun Hong , Choi Woorak , Doh Junsang , Lee Sang Joon 
Published: May 2017

AbstractSepsis causes multiple organs failures and eventually death. Changes in blood constituents due to sepsis lead to alterations in hemorheological properties, and cell adhesiveness. In this study, a new microfluidic system is proposed to measure temporal variations in biophysical properties of blood after injecting lipopolysaccharide (LPS) into a rat extracorporeal model underex vivocondition. To measure blood viscosity, the interfacial line between blood and a reference fluid is formed in a Y-shaped channel. Based on the relation between interfacial width and pressure ratio, the temporal variation in blood viscosity is estimated. Optical images of blood flows are analyzed by decreasing flow rate for examination of red blood cell (RBC) aggregation. Platelets initiated by shear acceleration around the stenosis adhere to the post-stenosed region. By applying a correlation map that visualizes the decorrelation of the streaming blood flow, the area of adhered platelets can be quantitatively attained without labeling of platelets. To assess sepsis inflammation, conventional biomarkers (PCT and IL-8) are also monitored. The increasing tendency for blood viscosity, RBC aggregation, platelet adhesion, and septic biomarkers are observed after LPS injection. This microfluidic system would be beneficial for monitoring the changes in hemorheological properties and platelet activation caused by sepsis.