bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Post‐Deployment Mental Health (PDMH) study and repository: A multi‐site study of US Afghanistan and Iraq era veterans
Authors: Brancu Mira , Wagner H. Ryan , Morey Rajendra A. , Beckham Jean C. , Calhoun Patrick S. , Tupler Larry A. , Marx Christine E. , Taber Katherine H. , Hurley Robin A. , Rowland Jared , McDonald Scott D. , Hoerle Jeffrey M. , Moore Scott D. , Kudler Harold S. , Weiner Richard D. ,   VA Mid‐Atlantic MIRECC Workgroup, Fairbank John A. 
Published: June 2017

AbstractThe United States (US) Department of Veterans Affairs (VA) Mid‐Atlantic Mental Illness Research, Education, and Clinical Center (MIRECC) Post‐Deployment Mental Health (PDMH) multi‐site study examines post‐deployment mental health in US military Afghanistan/Iraq‐era veterans. The study includes the comprehensive behavioral health characterization of over 3600 study participants and the genetic, metabolomic, neurocognitive, and neuroimaging data for many of the participants. The study design also incorporates an infrastructure for a data repository to re‐contact participants for follow‐up studies. The overwhelming majority (94%) of participants consented to be re‐contacted for future studies, and our recently completed feasibility study indicates that 73–83% of these participants could be reached successfully for enrollment into longitudinal follow‐up investigations. Longitudinal concurrent cohort follow‐up studies will be conducted (5–10+ years post‐baseline) to examine predictors of illness chronicity, resilience, recovery, functional outcome, and other variables, and will include neuroimaging, genetic/epigenetic, serum biomarker, and neurocognitive studies, among others. To date, the PDMH study has generated more than 35 publications from the baseline data and the repository has been leveraged in over 20 publications from follow‐up studies drawing from this cohort. Limitations that may affect data collection for a longitudinal follow‐up study are also presented.
The History and Composition of the Identified Human Skeletal Collection of the Certosa Cemetery (Bologna, Italy, 19th–20th Century)
Authors: Belcastro M. G. , Bonfiglioli B. , Pedrosi M. E. , Zuppello M. , Tanganelli V. , Mariotti V. 
Published: June 2017

AbstractThe purpose of this paper is to present the identified skeletal collection (by age, sex, cause of death, occupation and preservation state) from the Certosa Cemetery of Bologna (Italy), which was reviewed and checked through a consultation of the cemetery archives. The collection consists of 425 skeletons of individuals (from newborn to 91 years old) who died in Bologna between 1898 and 1944. The personal details associated with the skeletons were cross‐checked with the data contained in the cemetery and municipal archives. For each skeleton, the biological profile was assessed using current anthropological methods in order to confirm its correct identification. Four hundred and eighteen skeletons (98.4%), mostly complete and well preserved, are identified at least for sex, and for 95% of these, the age is known. The distribution of sexes in the various age groups is fairly well balanced. The cause of death is known in 93% of the individuals. Approximately 30% of the individuals died from infectious diseases. The occupation is known for more than 92% of the individuals. Most of the women were housewives, while the men were employed in various jobs. The cross‐check between archival data with the anthropological analysis of the remains enabled a reliable identification of the skeletons. The sexes and various age groups are well represented, and the sample is substantially uniform as far as geographical origin and socio‐economic conditions (lower social classes) are concerned. Thanks to the reliability of the information collected, the Certosa collection is an excellent anthropological tool for the development and validation of osteobiographic methods. Copyright © 2017 John Wiley & Sons, Ltd.
Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans
Authors: De Marinis Yang , Sun Jiangming , Bompada Pradeep , Domènech Omella Judit , Luan Cheng , Halu Arda , Renström Erik , Sharma Amitabh , Ridderstråle Martin 
Published: June 2017

ObjectiveNuclear receptor interacting protein 1 (NRIP1) is an important energy regulator, but few studies have addressed its role in humans. This study investigated adipose tissue and skeletal muscle NRIP1 gene expression and serum levels in response to weight loss and exercise in humans.MethodsNRIP1 expression was measured by microarray and serum NRIP1 by ELISA and Western blotting. Skeletal muscle transcriptomes were analyzed from Gene Expression Omnibus databases. Network‐based proximity analysis was performed on the proximity of NRIP1 interacting genes in the human interactome.ResultsIn patients with obesity, adipose tissue NRIP1 mRNA expression increased during weight loss and weight maintenance and showed strong associations with metabolic markers and anthropometric parameters. Serum NRIP1 protein levels also increased after weight loss. In skeletal muscle, imposed rest increased NRIP1 expression by 80%, and strength training increased expression by ∼25% compared to baseline. Following rest, NRIP1 expression became sensitive to insulin stimulation. After re‐training, NRIP1 expression decreased. Interactome analysis showed significant proximity of NRIP1 interacting partners to the obesity network/module.ConclusionsNRIP1 gene expression and serum levels are strongly associated with metabolic states such as obesity, weight loss, different types of exercise, and peripheral tissue insulin resistance, potentially as a mediator of sedentary effects.
Mechanically robust conductive carbon clusters confined ethylene methyl acrylate–based flexible composites for superior shielding effectiveness
Authors: Bhawal Poushali , Ganguly Sayan , Das Tushar Kanti , Mondal Subhadip , Das N.C. 
Published: June 2017

Arresting of conducting carbon black into polymeric matrix to develop flexible and light weight composite has been a widely practiced platform. Extensive development of telecommunication creates a major vexations regarding radiation pollution. Thereafter, we have been motivated to develop low‐cost, flexible composites of specialty carbon black VXC (Vulcan XC 72)–filled ethylene methyl acrylate (EMA) by mechanical mixing technique. Developed composite has significant conductivity (6.67 × 10−4 S cm−1) with promising mechanical and thermal properties. Dispersion of high‐structured carbon blacks in EMA was investigated by small angle X‐ray scattering to reflect the dependency of conducting mesh formation on dispersion. Interconnected filler network development has been visualized by field emission scanning electron microscope and high‐resolution transmission electron microscope. Electromagnetic interference shielding value in the X band has calculated to be 30.8 dB. Such features can make this EVXC (EMA‐Vulcan XC 72) composite a useful alternate for flexible electromagnetic interference shielding material.
Conditional abrogation of transforming growth factor‐β receptor 1 in PTEN‐inactivated endometrium promotes endometrial cancer progression in mice
Authors: Gao Yang , Lin Pengfei , Lydon John P , Li Qinglei 
Published: June 2017

AbstractAlthough a putative role for transforming growth factor‐β (TGFB) signalling in the pathogenesis of human endometrial cancer has long been proposed, the precise function of TGFB signalling in the development and progression of endometrial cancer remains elusive. Depletion of phosphatase and tensin homologue (PTEN) in the mouse uterus causes endometrial cancer. To identify the potential role of TGFB signalling in endometrial cancer, we simultaneously deleted TGFB receptor 1 (Tgfbr1) and Pten in the mouse uterus by using Cre‐recombinase driven by the progesterone receptor (termed Ptend/d;Tgfbr1d/d). We found that Ptend/d;Tgfbr1d/d mice developed severe endometrial lesions that progressed more rapidly than those resulting from conditional deletion of Pten alone, suggesting that TGFB signalling synergizes with PTEN to suppress endometrial cancer progression. Remarkably, Ptend/d;Tgfbr1d/d mice developed distant pulmonary metastases, leading to a significantly reduced lifespan. The development of metastasis and accelerated tumour progression in Ptend/d;Tgfbr1d/d mice are associated with increased production of proinflammatory chemokines, enhanced cancer cell motility, as shown by myometrial invasion and disruption, and an altered tumour microenvironment characterized by recruitment of tumour‐associated macrophages. Thus, conditional deletion of Tgfbr1 in PTEN‐inactivated endometrium leads to a disease that recapitulates invasive and lethal human endometrial cancer. This mouse model may be valuable for preclinical testing of new cancer therapies, particularly those targeting metastasis, one of the hallmarks of cancer and a major cause of death in endometrial cancer patients. Copyright © 2017 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Loss of coordination in complex directed networks: An incremental approach based on matrix measures
Authors: Russo Giovanni 
Published: June 2017

SummaryThis paper is concerned with the problem of understanding the dynamical mechanisms responsible for the loss of a desired behavior in complex directed networks. Specifically, we give 2 sufficient conditions for the desynchronization of a directed complex network, which are based on the use of matrix measures. The effectiveness of our approach is shown on 2 applications that are directly motivated by our research in smart cities and systems/synthetic biology.
High production of genistein diglucoside derivative using cyclodextrin glycosyltransferase from Paenibacillus macerans
Authors: Han Ruizhi , Ge Binbin , Jiang Mingyang , Xu Guochao , Dong Jinjun , Ni Ye 
Published: June 2017

Abstract
Genistein has been regarded as one important soy isoflavone with multiple health benefits, whereas its applications are limited by the low hydrophilicity. To improve the water solubility, codon optimized cyclodextrin glycosyltransferase from Paenibacillus macerans was employed for genistein transglycosylation in this study. At least four transglycosylation products were produced and identified by HPLC and LC–MS: genistein monoglucoside, diglucoside, triglucoside, and tetraglucoside derivatives. Obviously, the yields of genistein monoglucoside and genistein diglucoside exhibited great superiority compared with other two products. To maximize the yield of genistein diglucoside, various reaction conditions such as genistein dissolvents, glycosyl donors, substrates concentrations and ratios, enzyme concentrations, reaction pH, temperature, and time were optimized. Finally, the yield of genistein diglucoside was enhanced by 1.5-fold under the optimum reaction system. Our study demonstrates that the production of genistein diglucoside could be specifically enhanced, which is one important genistein derivative with better water solubility and stability.
Phenological specialisation of two ant‐dispersed sedges in relation to requirements for qualitative and quantitative dispersal effectiveness
Authors: Tanaka Koki , Tokuda Makoto 
Published: June 2017

AbstractSynchronisation of fruiting phenology with disperser activities is an important component of plant adaptation to seed dispersal mutualisms. Although most previous studies have exclusively evaluated the effects of fruiting phenology on seed removal rate, seed dispersal effectiveness is determined by both the number of dispersed seeds (quantitative effectiveness) and the probability of a dispersed seed becomes an adults (qualitative effectiveness). Therefore, the adaptive significance of fruiting phenology should be assessed for both components of dispersal effectiveness. This study investigates the adaptive significance of fruiting phenology for two ant‐dispersed sedges, Carex lanceolata and C. tristachya. Because C. lanceolata is known to require a longer seed dispersal distance than C. tristachya, we hypothesized that C. lanceolata produces seeds when high qualitative dispersal effectiveness can be achieved, while C. tristachya bears seeds when seed disperser ants are abundant to give priority to quantitative dispersal effectiveness. Field observations of ant activity around the sedges revealed that the relative abundance of ant species with the longest seed dispersal distance, Formica japonica, was higher during the fruiting period of C. lanceolata than in that of C. tristachya, which is consistent with the requirement of C. lanceolata to achieve high qualitative effectiveness. In addition, our fruiting manipulation experiment revealed that C. tristachya fruits when the overall seed removal rate is high, resulting in high quantitative effectiveness. Overall, our results support the idea that variations in both qualitative and quantitative dispersal effectiveness should be considered to understand the adaptive significance of fruiting phenology in animal‐dispersed plants.
Preconception and Prenatal Smoking among Maine Women: Defining Risk and Determining the Impact of Efforts by Care Providers to Promote Cessation
Authors: Harris David E. , Aboueissa AbouEl-Makarim A. , Sarton Cheryl , Baugh Nancy 
Published: June 2017

Introduction:Smoking before and during pregnancy is a risk for women and their babies, but encouraging tobacco abstinence challenges practitioners.Aims:We define correlates of tobacco use around pregnancy and determine the impact of providers’ efforts to encourage abstinence.Methods:We analysed responses (2000 – 2010) from the Pregnancy Risk Assessment Monitoring System questionnaire for Maine, United States, a state with higher than average smoking rates. We performed multivariable logistic regression analysis with demographic and behavioural independent variables, and smoking in the last 3 months before and in the last 3 months of pregnancy as dependent variables.Results:Of 12,409 questionnaire responders, 32% smoked before pregnancy; 60.5% of these women continued during pregnancy. Women were more likely to smoke before pregnancy and to continue during pregnancy if they had a previous birth, were unmarried, had ≤ a high school education, or had a household income ≤ $20,000/year. Pre-pregnancy smokers were more likely to continue smoking during pregnancy if their gestational weight gain was less than recommended and, surprisingly, if they recalled a provider discussion about smoking cessation.Conclusions:We identify women at risk for smoking before and during pregnancy and demonstrate that current tobacco abstinence interventions by providers may not always be effective.
Gender versus Culture Debates andDébâcles: Feminisms, Interculturalism and the Quebec Charter of Values
Authors: Dobrowolsky Alexandra 
Published: June 2017

AbstractQuebec's Bill 60 (or Charter of Values), legislation prohibiting public officials from wearing religious symbols and garb, provides a complicated case of a minority nation grappling with culture and gender, while also illustrating the more contingent condition of Canadian multiculturalism, equality and feminisms. Quebec has adoptedinterculturalismversusmulticulturalism; moreover, its multilayered women's movement remains a legitimate force, unlike in the rest of Canada. Despite the intricacies of these distinctive developments, this article reveals how Charter of Values justifications asserted the Quebec nation's distinctiveness and alleged egalitarian pre-eminence over others, not only homogenizing and instrumentalizing multiple cultures, but also various feminisms. Yet, when culture, gender equality and feminisms become reified and essentialized through a strategic depiction of certain minority women's rights, Canada's already well-worn claims to diversity and equality are further frayed both subnationally and nationally.
Intersectionality and Gendered Political Behaviour in a Multicultural Canada
Authors: Harell Allison 
Published: June 2017

AbstractResearch on gendered political behaviour has been heavily influenced by feminist scholarship in understanding gender inequalities. Yet it has been more difficult to integrate the insights of more recent waves of feminist critics, notably among intersectional scholars. The focus has been on differences between women and men, rather than among differently situated women. This article addresses the difficulties of integrating intersections into large-n style studies of political behaviour using “situated comparisons” (Dhamoon, 2010). It then provides an analysis of gender gaps in turnout and civic engagement across ethnoracial groups in Canada using the Ethnic Diversity Survey (2002).It concludes by arguing that the study of gender and political behaviour must find a place for intersectional feminist approaches.
Attached Advocacy and the Rights of the Trans Child
Authors: Manning Kimberley Ens 
Published: June 2017

AbstractOver the past five years transgender children and their parents have emerged as visible actors in public discussions about the rights of transgender people in Canada. In this article, I track the work of emotions in parent advocacy, showing how the enactment of filial (family) ties sheds new light on the gendered relationship between intimacy and political practice. I argue that an affective shift in parenting has opened up space for some cisgender parents to emerge as political actors in trans advocacy work. The affective politics of parent advocacy nonetheless operates through dominant frames of gendered, classed and racialized normativity, limiting both who can become a parent advocate and potentially narrowing the focus of the struggle.
Using camera traps to study the age–sex structure and behaviour of crop-using elephants Loxodonta africana in Udzungwa Mountains National Park, Tanzania
Authors: Smit Josephine , Pozo Rocío A. , Cusack Jeremy J. , Nowak Katarzyna , Jones Trevor 
Published: June 2017

AbstractCrop losses to foraging elephants are one of the primary obstacles to the coexistence of elephants and people. Understanding whether some individuals in a population are more likely to forage on crops, and the temporal patterns of elephant visits to farms, is key to mitigating the negative impacts of elephants on farmers’ livelihoods. We used camera traps to study the crop foraging behaviour of African elephants Loxodonta africana in farmland adjacent to the Udzungwa Mountains National Park in southern Tanzania during October 2010–August 2014. Camera traps placed on elephant trails into farmland detected elephants on 336 occasions during the study period. We identified individual elephants for 126 camera-trap detections. All were independent males, and we identified 48 unique bulls aged 10–29 years. Two-thirds of the bulls identified were detected only once by camera traps during the study period. Our findings are consistent with previous studies that found that adult males are more likely to adopt high-risk feeding behaviours such as crop foraging, although young males dispersing from maternal family units also consume crops in Udzungwa. We found a large number of occasional crop-users (32 of the 48 bulls identified) and a smaller number of repeat crop-users (16 of 48), suggesting that lethal control of crop-using elephants is unlikely to be an effective long-term strategy for reducing crop losses to elephants.
GRADE EVIDENCE TO DECISION (EtD) FRAMEWORK FOR COVERAGE DECISIONS
Authors: Parmelli Elena , Amato Laura , Oxman Andrew D. , Alonso-Coello Pablo , Brunetti Massimo , Moberg Jenny , Nonino Francesco , Pregno Silvia , Saitto Carlo , Schünemann Holger J. , Davoli Marina ,   the GRADE Working Group
Published: June 2017

Objectives: Coverage decisions are decisions by third party payers about whether and how much to pay for technologies or services, and under what conditions. Given their complexity, a systematic and transparent approach is needed. The DECIDE (Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence) Project, a GRADE (Grading of Recommendations Assessment, Development and Evaluation) Working Group initiative funded by the European Union, has developed GRADE Evidence to Decision (EtD) framework for different types of decisions, including coverage ones.Methods: We used an iterative approach, including brainstorming to generate ideas, consultation with stakeholders, user testing, and pilot testing of the framework.Results: The general structure of the EtD includes formulation of the question, an assessment using twelve criteria, and conclusions. Criteria that are relevant for coverage decisions are similar to those for clinical recommendations from a population perspective. Important differences between the two include the decision-making processes, accountability, and the nature of the judgments that need to be made for some criteria. Although cost-effectiveness is a key consideration when making coverage decisions, it may not be the determining factor. Strength of recommendation is not directly linked to the type of coverage decisions, but when there are important uncertainties, it may be possible to cover an intervention for a subgroup, in the context of research, with price negotiation, or with restrictions.Conclusions: The EtD provides a systematic and transparent approach for making coverage decisions. It helps ensure consideration of key criteria that determine whether a technology or service should be covered and that judgments are informed by the best available evidence.
Social Cognition Abilities in Patients With Different Multiple Sclerosis Subtypes
Authors: Henry Audrey , Tourbah Ayman , Chaunu Marie-Pierre , Bakchine Serge , Montreuil Michèle 
Published: June 2017

AbstractObjectives:Multiple sclerosis (MS) can be associated with impaired social cognition. However, social cognition skills have never been explored in the different subtypes of MS. The first aim of this study was to examine whether MS subtypes differ on the course of social cognition. The second aim was to explore the relationship between social cognition performances and executive abilities and mood variables.Methods:Sixty-two patients with MS and 33 healthy matched controls performed experimental tasks assessing facial emotion recognition, theory of mind (ToM), and cognitive functioning, in particular executive functions.Results:Patients differed from controls on both measures of social cognition. On the ToM measures, patients with progressive MS scored significantly lower than healthy participants. Patients with primary progressive MS performed worse than both healthy participants and patients with relapsing-remitting MS on the recognition of fearful facial expressions, while patients with secondary progressive MS performed worse on the recognition of facial expressions of sadness. Patients’ social cognition difficulties were correlated with processing speed, working memory, and verbal fluency.Conclusions:These preliminary results suggested that there may be qualitative differences in social cognition difficulties among the phenotypes. Furthermore, these impairments were related to executive functions, but unrelated to patients’ disability or level of depression. These data highlight the need for research to determine the real impact of these deficits on interpersonal relationships among patients and to confirm these disorders in a larger population with progressive forms of MS. (JINS, 2017,23, 653–664)