bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elongation of barley roots in high‐pH nutrient solution is supported by both cell proliferation and differentiation in the root apex
Authors: Higuchi Kyoko , Ono Kota , Araki Satoru , Nakamura Shogo , Uesugi Tetsuya , Makishima Taira , Ikari Atsushi , Hanaoka Takahiro , Sue Masayuki 
Published: April 2017

AbstractMany crops grow well on neutral or weakly acidic soils. The ability of roots to elongate under high‐external pH would be advantageous for the survival of plants on alkaline soil. We found that root elongation was promoted in some plant species in alkaline‐nutrient solution. Barley, but not tomato, root growth was maintained in pH 8 nutrient solution. Fe and Mn were absorbed well from the pH 8 nutrient solution by both barley and tomato plants, suggesting that the different growth responses of these two species may not be caused by insolubilization of transition metals. The ability of intact barley and tomato plants to acidify external solution was comparable; in both species, this ability decreased in plants exposed to pH 8 nutrient solution for 1 w. Conversely, cell proliferation and elongation in barley root apices were facilitated at pH 8 as shown by microscopy and cell‐cycle‐related gene‐expression data; this was not observed in tomato. We propose that barley adapts to alkaline stress by increasing root development.
Effects of ambient temperature in association with photoperiod on phenology and on the expressions of major plant developmental genes in wheat (Triticum aestivum L.)
Authors: Kiss Tibor , Dixon Laura E. , Soltész Alexandra , Bányai Judit , Mayer Marianna , Balla Krisztina , Allard Vincent , Galiba Gábor , Slafer Gustavo A. , Griffiths Simon , Veisz Ottó , Karsai Ildikó 
Published: April 2017

AbstractIn addition to its role in vernalization, temperature is an important environmental stimulus in determining plant growth and development. We used factorial combinations of two photoperiods (16H, 12H) and three temperature levels (11, 18 and 25 °C) to study the temperature responses of 19 wheat cultivars with established genetic relationships. Temperature produced more significant effects on plant development than photoperiod, with strong genotypic components. Wheat genotypes with PPD‐D1 photoperiod sensitive allele were sensitive to temperature; their development was delayed by higher temperature, which intensified under non‐inductive conditions. The effect of temperature on plant development was not proportional; it influenced the stem elongation to the largest extent, and warmer temperature lengthened the lag phase between the detection of first node and the beginning of intensive stem elongation. The gene expression patterns of VRN1, VRN2 and PPD1 were also significantly modified by temperature, while VRN3 was more chronologically regulated. The associations between VRN1 and VRN3 gene expression with early apex development were significant in all treatments but were only significant for later plant developmental phases under optimal conditions (16H and 18 °C). Under 16H, the magnitude of the transient peak expression of VRN2 observed at 18 and 25 °C associated with the later developmental phases.
TLR‐Stimulated Eosinophils Mediate Recruitment and Activation of NK Cells In Vivo
Authors: O'Flaherty S. M. , Sutummaporn K. , Häggtoft W. L. , Worrall A. P. , Rizzo M. , Braniste V. , Höglund P. , Kadri N. , Chambers B. J. 
Published: April 2017

AbstractEosinophils like many myeloid innate immune cells can provide cytokines and chemokines for the activation of other immune cells upon TLR stimulation. When TLR‐stimulated eosinophils were inoculated i.p. into wild‐type mice, and NK cells were rapidly recruited and exhibited antitumour cytotoxicity. However, when mice depleted of CD11c+ cells were used, a marked decrease in the number of recruited NK cells was observed. We postulated that CpG or LPS from the injected eosinophils could be transferred to host cells, which in turn could recruit NK cells. However, by inoculating mice deficient in TLR4 or TLR9 with LPS or CpG‐stimulated eosinophils respectively, NK cell recruitment was still observed alongside cytotoxicity and IFNγ production. CpG stimulation of eosinophils produced the pro‐inflammatory cytokine IL‐12 and the chemokine CXCL10, which are important for NK cell activation and recruitment in vivo. To demonstrate the importance of CXCL10 in NK cell recruitment, we found that CpG‐stimulated eosinophils pretreated with the gut microbial metabolite butyrate had reduced expression and production of CXCL10 and IL‐12 and concomitantly were poor at recruitment of NK cells and inducing IFNγ in NK cells. Therefore, eosinophils like other innate immune cells of myeloid origin can conceivably stimulate NK cell activity. In addition, products of the gut microbiota can be potential inhibitors of NK cell.
Subunit Vaccines Consisting of Antigens from Dormant and Replicating Bacteria Show Promising Therapeutic Effect against Mycobacterium Bovis BCG Latent Infection
Authors: Li F. , Kang H. , Li J. , Zhang D. , Zhang Y. , Dannenberg A. M. , Liu X. , Niu H. , Ma L. , Tang R. , Han X. , Gan C. , Ma X. , Tan J. , Zhu B. 
Published: April 2017

AbstractTo screen effective antigens as therapeutic subunit vaccines against Mycobacterium latent infection, we did bioinformatics analysis and literature review to identify effective antigens and evaluated the immunogenicity of five antigens highly expressed in dormant bacteria, which included Rv2031c (HspX), Rv2626c (Hrp1), Rv2007c (FdxA), Rv1738 and Rv3130c. Then, several fusion proteins such as Rv2007c‐Rv2626c (F6), Rv2031c‐Rv1738‐Rv1733c (H83), ESAT6‐Rv1738‐Rv2626c (LT40), ESAT6‐Ag85B‐MPT64<190‐198>‐Mtb8.4 (EAMM), and EAMM‐Rv2626c (LT70) were constructed and their therapeutic effects were evaluated in pulmonary Mycobacterium bovis Bacilli Calmette–Guérin (BCG) – latently infected rabbit or mouse models. The results showed that EAMM and F6 plus H83 had therapeutic effect against BCG latent infection in the rabbit model, respectively, and that the combination of EAMM with F6 plus H83 significantly reduced the bacterial load. In addition, the fusion proteins LT40 and LT70 consisting of multistage antigens showed promising therapeutic effects in the mouse model. We conclude that subunit vaccines consisting of both latency and replicating‐associated antigens show promising therapeutic effects in BCG latent infection animal models.
A Retrospective Study Assessing Safety and Efficacy of Bipolar Radiofrequency Ablation for Knee Chondral Lesions
Authors: Gharaibeh Monther , Szomor Andras , Chen Darren B. , MacDessi Samuel J. 
Published: April 2017

Objective: Bipolar radiofrequency (bRF) ablation is gaining popularity as a treatment modality for unstable knee chondral lesions of the knee. Limited reports of osteonecrosis and chondrolysis have been published; however, there is little data examining the safety of this treatment in larger series. This study aims to evaluate the safety and efficacy of bRF in the treatment of chondral lesions encountered during knee arthroscopy. Design: A retrospective evaluation of adverse outcomes in patients that underwent treatment of chondral lesions using bRF was undertaken. Secondary outcome measures included change in patient reported outcome scores and its correlation to patient demographics and quality of chondral and meniscal lesions using Chondropenia Severity Score. Results: Only 2.2% and 2.7% of the patients had a postoperative complication or required a reoperation, respectively. None of the complications were directly related to the use of bRF. A statistically significant difference was observed when comparing pre- and postoperative scores in all normalized categories ( P < 0.0001). No statistically significant correlation was found between change in self-reported scores and Chondropenia Severity Score. Conclusion: Bipolar radiofrequency ablation is a safe modality in treatment of chondral lesions.
Background and Principles of Customs Audit in the Republic Of Kazakhstan
Authors: Березюк  , Berezyuk V. 
Published: April 2017

Until recently, some leading economists considered revision as the main form of fi nancial control. At the same
time in the world practice there is such form of control, as the state audit, which joins the fi nancial audit, performance
audit and, in our opinion, the customs audit. Th e article considers problems of formation and development of the customs
audit in the Republic of Kazakhstan.
Wide Field Multicolor CCD Photometry of the Open Cluster NGC752
Authors: Zdanavičius J. , Bartašiutė S. , Zdanavičius K. 
Published: April 2017

AbstractThe results of CCD photometry in the seven-color Vilnius system of 3058 stars down to V ~ 18.0 mag in a 1.5 square degree field around the cluster NGC 752 are presented. For most of the stars brighter than V = 17.0 mag, photometric spectral and luminosity classes are determined. The catalog of 1174 stars down to V = 15.5 mag is given in the paper. The entire catalog will be available at the CDS Simbad database. The color-magnitude diagram indicates an extension of the cluster’s main sequence down to 5 mag below the turnoff point.
Multicolor CCD Photometry of the Open Cluster IC 361
Authors: Zdanavičius J. , Bartašiūtė S. , Boyle R. P. , Vrba F. J. , Zdanavičius K. 
Published: April 2017

AbstractCCD photometry in the eight-color Vilnius + I system for 7250 stars down to I =19.6 mag has been obtained in the 20′ × 26′ field of the open cluster IC 361 in Camelopardalis. The catalog of 1420 stars down to V ~ 18.5 mag is presented. It contains the coordinates, V magnitudes and seven color indices, quantitative photometric spectral types, absolute magnitudes and distances. The interstellar extinction is found to be non-uniform across the field, with the values of A
Changes in the Cloud Belts of Jupiter, 1630–1664, as Reported in the 1665 Astronomia Reformata of Giovanni Battista Riccioli
Authors: Graney Christopher M. 
Published: April 2017

Abstract
A translation of a section from the 1665 Astronomia Reformata of G. B. Riccioli discussing the appearance of the disk of Jupiter during the years 1630-1664; changes in the Jovian cloud belts as recorded by a variety of observers are a major feature of Riccioli’s discussion.
Empathy gap – what do we know about empathizing with others′ pain?
Authors: Dopierała Aleksandra , Jankowiak-Siuda Kamila , Boski Paweł 
Published: April 2017

Abstract
Empathy of pain as a multi-dimensional process includes sharing and understanding the pain of others in relation to oneself. Subjects in such studies are typically members of western, educated, industrialized, rich and democratic societies. In the literature review that we conducted, we observed that little is known about the empathy for pain in people who are not members of societies with these cultural characteristics. We often understand those who are “similar” to us more easily - ones who belong to “our” cultural circle. However, contact with another culture could help prevent such bias. Group characteristics, such as focus on others, hierarchy preference, or cultural differences in self-constructs, can change the activity of brain regions associated with empathy and compassion. Increasing the diversity of the research participants connected with education level, poverty, industrialization, and respect for basic citizen freedoms seem to be necessary to fully understand the mechanisms that influence the development and operation of empathy.
Extremely Locally Advanced Ovarian Malignant Mixed Mullerian Tumor in 37-Years-Old Female
Authors: Jota Gjorgji , Gelevski Radomir , Karadzov Zoran , Selmani Redzep , Genadieva-Dimitrova Magdalena , Peneva Margarita , Jovanovska-Manevska Vesna 
Published: April 2017

Abstract
Ovarian carcinosarcomas, rare variant of ovarian carcinoma, composed of both carcinomatous and mesenchymal components, solid and/or cystic, fleshy and hemorrhagic, frequently spreading beyond the ovary, are treated with surgery and adjuvant chemotherapy according to the treatment principles of ovarian carcinomas due to the small number of reported cases and lack of randomized studies. We report a case of a 37-year-old woman with clinical signs of extremely locally advanced tumor of ovarian origin, infiltrating the lower left quadrant of the abdominal wall with necrosis of the covering skin. Prior biopsy of the left ovary and omentum confirmed poorly differentiated serous adenocarcinoma. Bulky tumor the size of a child’s head, originating from the left ovary and infiltrating into the lower left quadrant abdominal wall was debulked with wide excision of the abdominal wall and creation of wide defect of the lower left part of abdominal wall covered with Dexon mesh. After the recovery, the medial part of the defect with exposed mesh was closed with pedicled tensor fasciae latae fasciomyocutaneous flap, while the lateral part of the defect was covered with split thickness skin graft. Optimal surgical cytoreduction and adjuvant chemotherapy in case of extremely locally advanced ovarian malignant Müllerian tumor provide satisfactory recurrence-free survival period.
KERAGAMAN 16 AKSESI JAMBU METE HASIL GRAFTING BERDASARKAN KARAKTER MORFOLOGI
Authors: Haryudin Wawan , Rostiana Otih 
Published: April 2017

<p class="IsiabstrakIndonesia">Jambu mete merupakan tanaman menyerbuk silang, yang biasa diperbanyak dengan biji. Salah satu upaya penyediaan tanaman agar sama sifatnya dengan induknya adalah dengan grafting. Oleh karena itu, dalam konservasi plasma nutfah jambu mete, tanaman hasil eksplorasi diperbanyak dengan cara grafting. Penelitian bertujuan untuk mengetahui tingkat keragaman tanaman hasil grafting 16 aksesi jambu mete asal Sulawesi Tenggara berdasarkan karakter morfologi. Penelitian dilakukan di Kebun Percobaan Cikampek, Januari sampai Desember 2015 dengan melakukan observasi langsung terhadap individu tanaman. Batang bawah yang digunakan adalah varietas B02, sedangkan batang atas adalah 16 aksesi hasil eksplorasi dari beberapa daerah di Sulawesi Tenggara. Pengamatan karakteristik morfologi secara kualitatif dan kuantitatif dilakukan terhadap tanaman hasil grafting umur 4 tahun. Tingkat keragaman 16 aksesi jambu mete asal Sulawesi Temggara bervariasi pada karakter bentuk daun, bentuk basal dan ujung daun, bentuk tajuk, arah percabangan serta warna daun muda dan tua. Karakter bentuk tepi daun, bentuk permukaan daun bagian atas dan bawah tidak bervariasi. Tingkat keragaman morfologi daun berkisar 67,18-87,59%, terbagi menjadi dua kelompok yang dipisahkan oleh karakter warna daun muda dan arah percabangan. Karakter tinggi tanaman, lebar tajuk, panjang daun, lebar daun, tebal daun, dan panjang tangkai daun sangat bervariasi. Tingkat keragaman berkisar antara 77,44-95,91% terbagi menjadi dua kelompok besar yang dipisahkan oleh karakter tinggi tanaman, panjang tangkai daun dan lebar tajuk. Karakter tinggi tanaman memisahkan 16 aksesi jambu mete dalam dua kelompok dengan koefisien keragaman 77,45-95,46%. Pada tahap selanjutnya perlu dilakukan observasi terhadap produksi gelondong, untuk menentukan korelasi antara pembeda pada sifat morfologi jambu mete dengan produksi gelondong.</p>
Combining X‐ray Computed Tomography and Visible Near‐Infrared Spectroscopy for Prediction of Soil Structural Properties
Authors: Katuwal Sheela , Hermansen Cecilie , Knadel Maria , Moldrup Per , Greve Mogens H. , de Jonge L.W. 
Published: April 2017

Core Ideas
Vis‐NIR can be used for estimation of soil physical and structural properties.
Structural parameters are better predicted using vis‐NIR than pedotransfer functions.
Vis‐NIR can be a fast and reliable method for predicting soils' transport behavior.
Soil structure is a key soil property affecting a soil's flow and transport behavior. X‐ray computed tomography (CT) is increasingly used to quantify soil structure. However, the availability, cost, time, and skills required for processing are still limiting the number of soils studied. Visible near‐infrared (vis‐NIR) spectroscopy is a rapid analytical technique used successfully to predict various soil properties. In this study, the potential of using vis‐NIR spectroscopy to predict X‐ray CT derived soil structural properties was investigated. In this study, 127 soil samples from six agricultural fields within Denmark with a wide range of textural properties and organic C (OC) contents were studied. Macroporosity (>1.2 mm in diameter) and CTmatrix (the density of the field‐moist soil matrix devoid of large macropores and stones) were determined from X‐ray CT scans of undisturbed soil cores (19 by 20 cm). Both macroporosity and CTmatix are soil structural properties that affect the degree of preferential transport. Bulk soils from the 127 sampling locations were scanned with a vis‐NIR spectrometer (400–2500 nm). Macroporosity and CTmatrix were statistically predicted with partial least squares regression (PLSR) using the vis‐NIR data (vis‐NIR‐PLSR) and multiple linear regression (MLR) based on soil texture and OC. The statistical prediction of macroporosity was poor, with both vis‐NIR‐PLSR and MLR (R2 < 0.45, ratio of performance to deviation [RPD] < 1.4, and ratio of performance to interquartile distance [RPIQ] < 1.8). The CTmatrix was predicted better (R2 > 0.65, RPD > 1.5, and RPIQ > 2.0) combining the methods. The results illustrate the potential applicability of vis‐NIR spectroscopy for rapid assessment/prediction of CTmatrix.
Creating reproducible dynamic reports using data from the Secure Anonymised Information Linkage (SAIL) Databank
Authors: Wang Ting 
Published: April 2017

ABSTRACT
Introduction/BackgroundR, an open source analytical software has gained wide popularity for its powerful statistical and graphical techniques, little known is that it also proves to be a fantastic tool for generating automated, content specific documentation using a combination of extensible packages (i.e. R markdown, Pandoc, MiKTex, Knitr). One such example of using these techniques is to create content specific PDF reports for the 300 plus general practices in Wales who are contributing data to the Secure Anonymised Information Linkage (SAIL) Databank.
Objectives1). Create large number of automated PDF reports 2). Content specific to individual practice
ApproachThis project aimed to facilitate the production of a large number of similar reports (tailored to specific recipients) by reducing the repetition and manual effort required. This was done by using a combination of packages in R to create scripts to automate the production of large numbers of tailored reports that capture the characteristics of each individual practice.
ResultsThe output of this piece of work was a set of tailored reports for more than 300 Walsh general practices contributing data to the Secure Anonymised Information Linkage (SAIL) Databank up to 2015. The production of these reports was automated using a combination of R packages; the source code is flexible and can be applied to a range of contexts.
ConclusionMethods described in this talk is highly efficient and easy to adapt to different context (e.g. automate documentation for metadata)
The impact of cycle proficiency training on cycle-related behaviours and accidents in adolescence: findings from ALSPAC, a UK longitudinal cohort
Authors: Teyhan Alison , Cornish Rosie , Boyd Andy , Sissons Joshi Mary , Macleod John 
Published: April 2017

ABSTRACT
ObjectivesIn the UK, some children undertake National Cycle Proficiency Scheme [NCPS]/Bikeability training in primary school. It aims to promote cycling and safe cycling behaviours but there has been little scientific evaluation of its effectiveness. We aimed to examine the impact of cycle training on cycle-related behaviours and accidents in adolescence using self-report and hospital episode statistics (HES) data.
ApproachThe sample (n=5415) were participants in the Avon Longitudinal Study of Parents and Children who reported whether or not they had received NCPS training. Self-reported outcomes at 14 and 16 years included: cycling to school, ownership of cycle helmet, use of cycle helmet and high-visibility clothing on last cycle, and involvement in a cycle accident. Hospital admittance due to a cycle accident from 11-16 years was also included for a subsample (n=2222) who have been linked to HES. The association between cycle training and each of the outcomes was analysed using multilevel logistic regression (individual level 1, school level 2 [pseudo-ID of school attended obtained from linkage to National Pupil Database]), adjusted for a range of potential confounders.
ResultsApproximately 40% had received NCPS training. At 14 and 16 years, trained children were more likely to cycle to school (at 16 years: adjusted OR 1.56, 95% CI 1.20-2.02) and to own a helmet (16 years: 2.03, 1.72-2.41) than those who had not attended a course. They were also more likely to have worn a helmet on their last cycle at age 14 (1.26, 1.07-1.49), and to have worn high-visibility clothing at age 16 (1.70, 1.22-2.39). Training was not associated with self-reported involvement in a cycle accident, and only six participants with HES data had been admitted to hospital due to a cycle accident. Irrespective of training, results indicate very low use of high-visibility clothing (5%), very few girls cycling to school (<2%), and less than half of helmet owners wearing one on their last cycle. Ownership and use of helmets was particularly low in children from lower socio-economic position families.
ConclusionCycle training for children can have benefits that persist into adolescence. However, the low use of cycle helmets and high-visibility clothing indicate the further potential for interventions to encourage safe cycling behaviours in young people. Our hospital admissions outcome only captures individuals who sustained serious injuries; more minor cycle injuries would have been treated in A&E but a lack of detail in admission codes precludes analysis of such data.