bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship to place among Spanish immigrants in the United Kingdom: effects on perceived prejudice / Relación con el lugar de inmigrantes españoles residentes en Reino Unido: efectos en el prejuicio percibido
Authors: Vallejo-Martín Macarena , Moreno-Jiménez María-Pilar 
Published: November 2017

Spanish citizens have migrated to other European countries in recent years, looking for employment and new opportunities. This study examines the relationship to place developed by Spanish immigrants in the UK using residential satisfaction, place attachment and place identity. It also assesses the possible influence of these variables on perceived prejudice. Place was conceptualized as an interchangeable relationship between physical-spatial characteristics and social-human ones. With a sample of 474 participants, the results showed that people felt satisfied in their new places of residence and attached to them, although those places were largely not part of their identity. It was also noted that the longer the length of residence, the higher the levels of the psycho-environmental variables measured. However, higher income levels in the new country only had positive effects on residential satisfaction. Finally, with regard to perceived prejudice, residential satisfaction was the only explanatory factor with a residual effect (5.5%) in the sample dataset. However, taking into consideration length of residence, it was noted that for those residents who had lived in the country for more than five years, residential satisfaction was a key factor that explained 42.9% of perceived prejudice.
On Absolutely Normal and Continued Fraction Normal Numbers
Authors: Becher Verónica , Yuhjtman Sergio A 
Published: November 2017

AbstractWe give a construction of a real number that is normal to all integer bases and continued fraction normal. The computation of the first n digits of its continued fraction expansion performs in the order of n4 mathematical operations. The construction works by defining successive refinements of appropriate subintervals to achieve, in the limit, simple normality to all integer bases and continued fraction normality. The main difficulty is to control the length of these subintervals. To achieve this we adapt and combine known metric theorems on continued fractions and on expansions in integers bases.
Coupled Kähler–Einstein Metrics
Authors: Hultgren Jakob , Witt Nyström D 
Published: November 2017

AbstractWe propose new types of canonical metrics on Kähler manifolds, called coupled Kähler–Einstein metrics, generalizing Kähler–Einstein metrics. We prove existence and uniqueness results in the cases when the canonical bundle is ample and when the manifold is Kähler–Einstein Fano. In the Fano case, we also prove that existence of coupled Kähler–Einstein metrics imply a certain algebraic stability condition, generalizing K-polystability.
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics
Authors: Li Ying Hong , Yu Chun Yan , Li Xiao Xu , Zhang Peng , Tang Jing , Yang Qingxia , Fu Tingting , Zhang Xiaoyu , Cui Xuejiao , Tu Gao , Zhang Yang , Li Shuang , Yang Fengyuan , Sun Qiu , Qin Chu , Zeng Xian , Chen Zhe , Chen Yu Zong , Zhu Feng 
Published: November 2017

Abstract
Extensive efforts have been directed at the discovery, investigation and clinical monitoring of targeted therapeutics. These efforts may be facilitated by the convenient access of the genetic, proteomic, interactive and other aspects of the therapeutic targets. Here, we describe an update of the Therapeutic target database (TTD) previously featured in NAR. This update includes: (i) 2000 drug resistance mutations in 83 targets and 104 target/drug regulatory genes, which are resistant to 228 drugs targeting 63 diseases (49 targets of 61 drugs with patient prevalence data); (ii) differential expression profiles of 758 targets in the disease-relevant drug-targeted tissue of 12 615 patients of 70 diseases; (iii) expression profiles of 629 targets in the non-targeted tissues of 2565 healthy individuals; (iv) 1008 target combinations of 1764 drugs and the 1604 target combination of 664 multi-target drugs; (v) additional 48 successful, 398 clinical trial and 21 research targets, 473 approved, 812 clinical trial and 1120 experimental drugs, and (vi) ICD-10-CM and ICD-9-CM codes for additional 482 targets and 262 drugs against 98 disease conditions. This update makes TTD more useful for facilitating the patient focused research, discovery and clinical investigations of the targeted therapeutics. TTD is accessible at http://bidd.nus.edu.sg/group/ttd/ttd.asp.
Habitual Snoring at Age 3 Years: Links with Parent-Rated Remembering in Daily Life and Academic Achievement at Age 7 Years
Authors: Luo Rebekah , Galland Barbara C. , Gill Amelia I. , Dawes Patrick , Schaughency Elizabeth 
Published: November 2017

ABSTRACT:

Objective:
Habitual snoring in school-aged children is well known to link with poorer cognitive functioning and academic performance, but few studies have explored later developmental outcomes related to snoring initiated in early childhood. The aims of this study were to examine whether habitual snoring at age 3 years predicted perceived memory and academic functioning at age 7 years.

Methods:
Parents (n = 460) of children aged 7 years 2 ± 5 months completed a community follow-up survey about their perceptions of their child's sleep and health, memory in daily activities, and academic performance relevant to numeracy and literacy skills. The first survey was completed by 839 parents 4 years prior when children were aged 3 years (54.8% response rate at age 7 years). Parents rated their child's academic performance twice. First, they rated performance based on teachers' feedback relative to national standard ratings for numeracy and literacy, and second, based on their own observations.

Results:
Children reported to snore habitually at age 3 years received lower memory and academic composite score ratings at age 7 years. Age 3 years habitual snoring history predicted small but significant unique variation in age 7 years memory (p = 0.005), literacy (p < 0.001), and overall achievement ratings (p = 0.016) in regressions controlling for covariates, with evidence suggesting that memory may mediate links between snoring history and academic performance.

Conclusion:
The findings suggest that habitual snoring in early childhood may adversely affect success in beginning schooling. More research is still needed to determine the best time for treatment so that longer-term consequences of sleep-disordered breathing may be prevented.
Effect of Pulmonary Rehabilitation on Inspiratory Capacity During 6-min Walk Test in Patients With COPD
Authors: Spielmanns Marc , Boeselt Tobias , Nell Christoph , Eckhoff Jenny , Koczulla Rembert Andreas , Magnet Fridericke Sophie , Storre Jan Hendrik , Windisch Wolfram , Baum Klaus 
Published: November 2017

Purpose:
Purpose of this study was to analyze the impact of a pulmonary rehabilitation (PR) program on the measured inspiratory capacity (IC) in patients with chronic obstructive pulmonary disease (COPD) while performing a 6-min walk test (6MWT).

Methods:
Before and after PR, IC was measured by spirometry both at the beginning and at the end of the 6MWT for 15 patients with COPD in the PR group (PRG) and compared with a similar calisthenics training group (CTG; n = 15). In addition, the COPD Assessment Test (CAT), St George's Respiratory Questionnaire (SGRQ), and other lung function tests were recorded and compared.

Results:
Both groups were not significantly different at baseline. Compared with the CTG, the PRG achieved a significant increase in the delta of IC measured during the 6MWT (0.5 ± 0.2 L [PRG] vs −0.2 + 0.2 L [CTG], P = .001). Significant differences were found for the 6MWT walking distance (PRG: 99 ± 36 m vs CTG: 5 ± 25 m, P = .001). No significant increase in dyspnea while performing the 6MWT was found in either group. The differences in the CAT score and the SGRQ Global score were significant only for the PRG in intragroup comparisons, whereas the intergroup comparison showed no significant differences. Except for residual volume, no significant changes in all parameters of the static lung function tests were observed in either group.

Conclusion:
Participation in a PR may lead to a significant and clinically relevant increase in IC and the walking distance. Additional research is necessary to define the effects of this increase in IC on exercise capacity.
Effect of Smoking Status on Exercise Perception and Intentions for Cardiac Rehabilitation Enrollment Among Patients Hospitalized With an Acute Cardiac Condition
Authors: Riley Hayden , Headley Samuel , Winter Christa , Mazur Sara , Gaalema Diann E. , Goff Sarah , Lindenauer Peter K. , Pack Quinn R. 
Published: November 2017

Purpose:
Cardiac rehabilitation (CR) attendance has been associated with higher smoking cessation (SC) rates. However, for unclear reasons, smokers are consistently less likely to enroll in CR than nonsmokers, and it is uncertain what might encourage them to attend.

Methods:
We surveyed patients eligible for CR who were cigarette smokers at the time of hospital admission. We assessed patient intention to quit smoking, start exercising, and enroll in CR. We also measured anxiety and depression levels.

Results:
Of the 105 patients approached, 81 (77%) completed the survey (69% males, aged 57 ± 10 y, 72% white). Most patients reported interest in SC (80%) and attending CR (78%). Many felt that SC medications (41%), stress management programs (35%), and an exercise program with SC counseling (30%) would increase their likelihood to attend CR; however, 30% stated that they would be less likely to enroll in CR if they continued smoking following discharge. Many patients indicated high levels of anxiety (51%) and depression (27%); many desired to reduce stress following discharge (73%), with 35% stating that stress management programs would increase their likelihood to attend CR.

Conclusions:
Hospitalized smokers eligible for CR report significant interest in SC, attending CR, and beginning an exercise program. These patients show high levels of anxiety and depression and indicate a strong interest in stress management programs. These results suggest that messages emphasizing the role of CR in the treatment of depression, anxiety, and stress are likely to resonate with smokers, increase their enrollment in CR, and support long-term SC.
Exploring the Views of Individuals With Chronic Obstructive Pulmonary Disease on the Use of Rollators
Authors: Holz Alanna , Bennett Amanda , Freethy Amber , Rossi Nadia , Tanzos Megan , Goldstein Roger , Brooks Dina , Harrison Samantha L. 
Published: November 2017

Purpose:
Although it has been well documented that the progressive exercise limitation associated with chronic obstructive pulmonary disease can be helped with an assistive device, such as a rollator, many individuals use it infrequently. This study seeks to explore the views of individuals with chronic obstructive pulmonary disease regarding the use of rollators.

Methods:
A qualitative study design was used. Twelve individuals with moderate to very severe chronic obstructive pulmonary disease were recruited from an outpatient pulmonary rehabilitation program to participate in semistructured interviews. Inductive thematic analysis was applied.

Results:
Analysis revealed 5 themes: (1) “acquiring a rollator” reflecting the process of obtaining a device either via a health care professional or self-referral; (2) “acceptance versus resistance” describing opposing views regarding rollator usage; (3) “rollator roadblocks” describing practical barriers to use; (4) “participation” reflecting how rollators can promote reintegration into society; and (5) “revising perceptions” whereby participants embodied an eventual acceptance of rollators.

Conclusion:
Rollator acquisition appeared to be a unilateral, prescriptive process. Individuals described initial resistance to use, although in the long-term, negative perceptions were outweighed by the functional and social benefits of rollator use. Encouraging users to participate in deciding whether to use a rollator and providing adequate education on its indications, benefits, barriers, and facilitators are likely to promote optimal use of a rollator.
A Mysterious Case of a Breast Lump in a Woman From the Philippines
Authors: Rennert-May Elissa , Dixit Devika 
Published: November 2017

Abstract
We present the case of a 74-year-old woman who recently emigrated from the Philippines to Canada, with an unusual etiology for her breast lump. Based on review of breast histopathology by a pathologist, as well as parasitology specialist and clinical history, the causative organism of this breast lump was Schistosoma japonicum. This is an uncommon manifestation of schistosomiasis, which causes more than 40 million clinical infections annually.
Medicaid Coverage of Methadone Maintenance and the Use of Opioid Agonist Therapy Among Pregnant Women in Specialty Treatment
Authors: Bachhuber Marcus A. , Mehta Pooja K. , Faherty Laura J. , Saloner Brendan 
Published: November 2017

Background:
Opioid agonist therapy (OAT) is the standard of care for pregnant women with opioid use disorder (OUD). Medicaid coverage policies may strongly influence OAT use in this group.

Objective:
To examine the association between Medicaid coverage of methadone maintenance and planned use of OAT in the publicly funded treatment system.

Research Design:
Retrospective cross-sectional analysis of treatment admissions in 30 states extracted from the Treatment Episode Data Set (2013 and 2014).

Subjects:
Medicaid-insured pregnant women with OUD (n=3354 treatment admissions).

Measures:
The main outcome measure was planned use of OAT on admission. The main exposure was state Medicaid coverage of methadone maintenance. Using multivariable logistic regression models adjusting for sociodemographic, substance use, and treatment characteristics, we compared the probability of planned OAT use in states with Medicaid coverage of methadone maintenance versus states without coverage.

Results:
A total of 71% of pregnant women admitted to OUD treatment were 18–29 years old, 85% were white non-Hispanic, and 56% used heroin. Overall, 74% of admissions occurred in the 18 states with Medicaid coverage of methadone maintenance and 53% of admissions involved planned use of OAT. Compared with states without Medicaid coverage of methadone maintenance, admissions in states with coverage were significantly more likely to involve planned OAT use (adjusted difference: 32.9 percentage points, 95% confidence interval, 19.2–46.7).

Conclusions:
Including methadone maintenance in the Medicaid benefit is essential to increasing OAT among pregnant women with OUD and should be considered a key policy strategy to enhance outcomes for mothers and newborns.
Valgus Hindfoot Deformity Secondary to Neonatal Intravenous Infiltration
Authors: Villarreal Eric D. , Konofaos Petros , Kelly Derek M. 
Published: November 2017

Abstract
Orthopedic complications of intravenous (IV) infiltration are rare, with only a handful of cases reported in the literature. Because of the relatively high rate of IV infiltration in neonates, however, such complications do occur and can include growth arrest, limb length discrepancy, and joint deformities that require surgical intervention. The risk of these complications is highest in preterm neonates. A 7-year-old girl presented to our institution with a severe valgus hindfoot deformity that developed secondary to a neonatal IV infiltration injury. Management consisted of a medial displacement calcaneal osteotomy followed 5 years later by a triple arthrodesis, Strayer procedure, and free flap transfer.
Internal Distraction Resulted in Improved Patient-Reported Outcomes for Midface Hypoplasia
Authors: Hindin David I. , Muetterties Corbin E. , Lee Justine C. , Kumar Anand , Kawamoto Henry K. , Bradley James P. 
Published: November 2017

Background:
Both internal and external distraction devices have been used successfully in correcting midface hypoplasia. Although the indication for surgery and the osteotomy techniques may be similar, deciding when to use internal versus external devices has not been studied. The authors studied patient-reported outcomes with FACE-Q and functional surveys for internal and external devices for midface distraction patients.

Methods:
Patients who underwent distraction advancement after Le Fort I and Le Fort III were surveyed using the FACE-Q survey and a functional survey. Equal groups of internal and external device patients were compared (n = 64). Data recorded included: sex, age, follow-up, diagnosis, operating room time, expected blood loss, length of stay, distraction length, consolidation time, and complications.

Results:
Internal and external device groups were similar with regards to patient diagnosis, operative time, expected blood loss, distraction length but consolidation times differed (internal = 3.6 versus external = 1.1 months). For FACE-Q appearance appraisal, there were similarities in domain and scale. For the functional survey (airway/breathing, ocular/vision, occlusion/eating, speech/articulation), there was also similar scoring. However, internal device patients had superior FACE-Q scores for Quality of Life: Social Function (80.9 versus 68.9), Early Life Impact (92.9 versus 62.4), Dental Anxiety (70.2 versus 48.3), Psychological Well-being (87.8 versus 68.6); and Decision Satisfaction (81.2 versus 56.9) and Outcome Satisfaction (91.0 versus 84.7).

Conclusions:
Internal and external midface distraction patients had similar patient-reported outcomes for appearance and functional improvement; however, internal device patients were more satisfied with their quality of life and their decision to undergo the procedure.
A Personal Approach to Bilateral Cleft Lip Repair
Authors: Austen William Gerald , Gfrerer Lisa , Lewis Michael B. 
Published: November 2017

Abstract
Dr Michael B. Lewis has been using his personal approach to bilateral cleft lip (BCL) repair for 30 years to achieve a loose, pouting upper lip, a 90-degree columellar-labial angle, and a projecting nasal tip. This article describes technique and results.
Use of Acellular Dermal Matrix in Craniosynostosis
Authors: Madaree Anil 
Published: November 2017

Abstract
In craniofacial surgery, a wide spectrum of pathological conditions are usually treated. The aetiology of these could be congenital, traumatic, infective, post-tumor resection, postradiation, autoimmune, iatrogenic, or other miscellaneous conditions. The surgical approach for the procedures is usually via a coronal incision. In a large proportion of the patients, the frontal bone is removed to obtain intracranial access. The frontal bone is then replaced either in its original form or in a remodeled state. In congenital conditions the supraorbital bar and frontal bone is often also removed, remodeled, and replaced. One of the common late sequelae following craniofacial surgery is contour irregularities of the frontal region. These irregularities can vary in their extent. They are invariably palpable and often visible. Surgeons have attempted various methods to improve the contour irregularities. Despite these measures contour irregularities can still ensue. In the authors’ unit, the authors have been using acellular dermal matrix in an attempt to diminish the contour irregularities in the frontal region following craniofacial reconstruction for craniosynostosis. This has been used in 35 patients undergoing craniosynostosis correction. Of the 35 patients, 12 were for plagiocephaly, 7 for brachycephaly, 10 for scaphocephaly, 4 for trigonocephaly, and 2 for combined coronal and metopic synostosis. The age of the patients ranged from 5 months to 12 years (mean 20.5 months). There were 21 males and 14 females. The follow-up ranged from 10 to 48 months (mean 23 months).
Optic Nerve Head Drusen: The Relationship Between Intraocular Pressure and Optic Nerve Structure and Function
Authors: Nolan Kaitlyn W. , Lee Michael S. , Jalalizadeh Rohan A. , Firl Kevin C. , Van Stavern Gregory P. , McClelland Collin M. 
Published: November 2017

Objective:
To determine whether at the time of diagnosis, the intraocular pressure (IOP) in patients with optic nerve head drusen (ONHD) correlates with the perimetric mean deviation (PMD) and the mean retinal nerve fiber layer (RNFL) thickness on optical coherence tomography (OCT).

Methods:
This retrospective chart review included adults with ONHD from 2 academic medical centers. Inclusion criteria were age older than 18 years, definitive diagnosis of ONHD, measurement of IOP, and an automated visual field (VF) within 3 months of diagnosis. Exclusion criteria were unreliable VFs, use of IOP-lowering therapy, and visually significant ocular comorbidities. Data were collected from the initial visit. Age, IOP, method of diagnosis of ONHD, mean RNFL thickness, and PMD were recorded. Multiple and logistic regression models were used to control for potential confounders in statistical analyses.

Results:
Chart review identified 623 patients, of which 146 patients met inclusion criteria. Mean age was 44.2 years (range: 19–82 years). Average PMD of 236 eyes was −5.22 dB (range, −31.2 to +1.21 dB). Mean IOP was 15.7 mm Hg (range: 6–24 mm Hg). Forty eyes (16.9%) underwent RNFL measurement using OCT; mean RNFL thickness was 79.9 μm (range: 43–117 μm). There was no statistically significant association between IOP and PMD (P = 0.13) or RNFL thickness (P = 0.65). Eyes with ocular hypertension tended to have less depressed PMD than those without (P= 0.031). Stratified analyses of visible and buried subgroups yielded similar results.

Conclusions:
Lowering IOP in patients with ONHD has been proposed as a means to prevent progression of optic neuropathy. Our study demonstrated that among predominately normotensive eyes, higher IOP was not associated with greater VF loss or thinner RNFL at the time of presentation. This suggests that lowering IOP may not be beneficial in preventing visual loss in normotensive eyes with ONHD.
Reflections on learning as designing
Authors: Bunnell Pille 
Published: November 2017

Purpose
This study aims to explore, illuminate and hence evoke further reflections on the implications of creating and conserving distinctions that inherently act as simplifications and limit appropriate action.

Design/methodology/approach
The approach used was reflective regarding the chosen concept of designing and learning from the perspective of a constitutive epistemology. These were investigated as circularities and as distinctions in language. The variety of intended meanings and hence implicit entailments was examined from the perspective of implicit domains.

Findings
A tendency to focus on the results of designing and learning rather than the processes was attributed to several factors including cultural relevance, tangibility, durability and observability. Further, it was found that result and process are arbitrary distinctions in a circular system. It was noted that lack of awareness of multiple domains encourages reification, and that distinctions inherently obscure what happens in the non-articulated aspects of living. However, expertise embraces an ability to attend to such “betweens”. This applies to expertise in the assessment of learning and designing.

Originality/value
The most obvious value of the findings is for the field of education. The insights gained indicate that the path of individualized learning with an emphasis on attention to the processes, inclusive of those that are not distinguished and named but can, with reflective experience, be sensed and acted on, has deep epistemological roots. A further implication is that educators require expertise to effectively work with learners, and that effective assessment depends on recurrent conversational interactions between the educator and learner.