bluuebunny/crossref_metadata_2025_split huggingface dataset:
La communication de crise
Authors: Boccard Patrick 
Published: August 2017

Les difficultés économiques, les maladresses de gestion, les « affaires », les accidents techniques graves... peuvent constituer pour les grandes entreprises des situations de crise que les directions de la communication sont amenées à gérer en urgence dans le but d’éviter la catastrophe. Un préalable est nécessaire, c’est à la fois l’analyse des causes de la crise et le repérage de la population directement concernée par les méfaits. Il convient alors de choisir les meilleurs vecteurs pour montrer quelles sont les solutions adaptées pour dépasser le danger et permettre à l’entreprise de mieux rebondir.
Good luck or good management? Multigenerational family control in two Swiss enterprises since the 19th century
Authors: Müller Margrit 
Published: August 2017

Quels ont été les moyens utilisés dans deux firmes suisses, Chemische Fabrik Ütikon et von Moos Stahl, pour préserver le contrôle d’une famille sur la propriété du capital et sur le personnel de direction pendant plus de 6 générations ? Ils ont été influencés par la répartition du capital, le modèle coutumier de succession dans chaque famille et l’expérience spécifique de chaque firme en matière de management par une famille. Les conflits de succession ont été largement évités en limitant le nombre de membres de la famille présents dans l’entreprise et en diversifiant les modes de participation de la famille. La continuité dynastique a été assurée face aux changements du contexte économique et institutionnel en modifiant le système de contrôle et en élargissant le périmètre de la firme familiale. L’article présente les avantages et les inconvénients de certaines caractéristiques du contrôle par une famille lorsque la firme doit s’adapter à ces changements, notamment l’effet ambigu de l’horizon à long terme des actionnaires membres de la famille ou la capacité de prise de risque des patrons propriétaires. La législation suisse sur les sociétés a donné une grande liberté de manœuvre en relâchant peu à peu les liens entre la firme et la famille.
L’aide à la décision entre outils et organisation
Authors: David Albert 
Published: August 2017

La décision est une dimension fondamentale de la vie des organisations, que l’on en ait une conception étroite - la décision signe la fin de la phase de délibération - ou très large - la décision est l’ensemble des processus cognitifs et relationnels qui conduisent à un choix et en permettent ensuite l’évaluation. Les outils d’aide à la décision qui ont été élaborés au cours de l’histoire des organisations et des techniques de management sont extrêmement variés. Leur succession reflète également l’évolution et la diversité des philosophies, des épistémologies et des méthodologies au nom desquelles ils ont été introduits, utilisés dans l’histoire des organisations. Au-delà d’une typologie descriptive des outils, nous allons répondre, dans cet article, à deux questions principales. Les outils d’aide à la décision présentent-ils des propriétés structurelles spécifiques ? A l’aide de quels concepts peut-on analyser et comprendre la dynamique de leur introduction dans les organisations ?
Savoir organisationnel, savoir théorique et situation : le contrôle statistique sur échantillons
Authors: Bayart Denis 
Published: August 2017

Le contrôle statistique de qualité est un ensemble de méthodes de gestion qui mettent en jeu deux types de savoirs : des savoirs théoriques, de type mathématique, et des savoirs organisationnels qui font le lien entre les premiers et les situations d’utilisation. Partant de l’hypothèse qu’un savoir théorique nécessite une forme concrète pour être utilisé, nous analysons, sur des exemples tirés de l’histoire, les relations entre ces deux types de savoirs, montrant comment ils se composent pour donner une gamme d’outils de gestion opérationnels. Le concept de savoirs organisationnels permet d’expliquer comment une même technique statistique, le jugement sur échantillon, peut prendre différentes formes concrètes (en particulier les tables d’échantillonnage) et être utilisée à des fins très variées.
Un exemple français d’acquisition de capacités organisationnelles : Alais, Froges et Camargue (AFC-Pechiney) d’une avant-guerre à l’autre
Authors: Cailluet Ludovic 
Published: August 2017

Chimiste et producteur d’aluminium, la compagnie Pechiney entre 1910 et 1939 a connu une croissance considérable, souvent par le biais de fusions et d’acquisitions. Comment s’est constituée au sein de cette firme une pratique de gestion systématique et adaptée ? Quelle est la part des modèles, des hommes et de la contingence dans les réformes de la gestion d’une grande entreprise ? Grâce au « cas Pechiney », cet article cherche à faire la part de ses facteurs à l’aide d’exemples concrets d’importation et d’adaptation d’instruments de gestion. Il affirme enfin l’importance de l’analyse historique des techniques de gestion pour saisir la performance de la compagnie Pechiney dans la période.
Les soins palliatifs en néonatologie : une revue de littérature
Authors: Koliouli Flora , Casper Charlotte , Berdot-Talmier Laurence , Zaouche-Gaudron Chantal 
Published: August 2017

L’objectif de cet article est d’établir un état des connaissances sur les soins palliatifs en néonatologie afin de réfléchir sur de nouvelles perspectives tant professionnelles que de recherche. Nous avons utilisé la littérature publiée de 2005 à 2016, disponible sur les bases de données électroniques (Francis, Medline, PsychInfo) en langue anglaise et/ou française. Deux pôles importants sont relevés : les études axées sur les pratiques professionnelles en soins palliatifs et celles focalisées sur les parents et leur vécu ; les études portant sur le point de vue des soignants mettent l’accent sur la nécessité d’une formation et la formalisation des interventions auprès des professionnels de santé. Ces dernières portent sur des aspects médicaux de la gestion de la douleur chez le nouveau-né en soins palliatifs mais également sur ses compétences communicatives et relationnelles. Le burnout des professionnels est également mis en avant. Deux aspects principaux sont soulignés dans les études qui portent sur les parents : leur rôle en tant que parents vis-à-vis de la prise de décision quant à la fin de vie, et, leur propre vécu. À la suite de notre analyse sur ces recherches tant nationales qu’internationales, nous avons pu dégager pour de futures recherches et l’amélioration des pratiques professionnelles.
CCR7 Deficiency Allows Accelerated Clearance of Chlamydia from the Female Reproductive Tract
Authors: Li Lin-Xi , Labuda Jasmine C. , Imai Denise M. , Griffey Stephen M. , McSorley Stephen J. 
Published: August 2017

Abstract
Immune mechanisms responsible for pathogen clearance from the female reproductive tract (FRT) are incompletely defined; in particular, the contribution of lymphocyte trafficking to this process is unclear. CCR7-deficient mice have profoundly altered lymphocyte recirculation and display ectopic formation of lymphocyte aggregates within mucosal nonlymphoid tissues, including the FRT. In this study, we investigated how altered lymphocyte distribution in CCR7-deficient mice would affect host responses to Chlamydia muridarum within the reproductive tract. As expected, CCR7-deficient mice exhibited reduced lymphocyte trafficking to lymph nodes and a corresponding increase in T cell populations within the FRT. After intravaginal infection with Chlamydia, CCR7-deficient mice displayed markedly reduced Ag-specific CD4 T cell responses within the local draining iliac lymph nodes, yet robust Th1 and Th17 responses were prominent in the FRT. In addition, Chlamydia-specific Ab responses were dysregulated in CCR7-deficient mice, displaying an unexpected increase in the systemic IgA responses. Importantly, prominent mucosal immune responses in CCR7-deficient mice increased the efficiency of bacteria clearance from the FRT while reducing tissue-associated inflammation and pathology. Thus, increased numbers of lymphocytes within the FRT result in pathogen clearance with reduced immune-mediated pathology.
IL-4/IL-13 Heteroreceptor Influences Th17 Cell Conversion and Sensitivity to Regulatory T Cell Suppression To Restrain Experimental Allergic Encephalomyelitis
Authors: Barik Subhasis , Ellis Jason S. , Cascio Jason A. , Miller Mindy M. , Ukah Tobechukwu K. , Cattin-Roy Alexis N. , Zaghouani Habib 
Published: August 2017

Abstract
IL-4 and IL-13 have been defined as anti-inflammatory cytokines that can counter myelin-reactive T cells and modulate experimental allergic encephalomyelitis. However, it is not known whether endogenous IL-4 and IL-13 contribute to the maintenance of peripheral tolerance and whether their function is coordinated with T regulatory cells (Tregs). In this study, we used mice in which the common cytokine receptor for IL-4 and IL-13, namely the IL-4Rα/IL-13Rα1 (13R) heteroreceptor (HR), is compromised and determined whether the lack of signaling by endogenous IL-4 and IL-13 through the HR influences the function of effector Th1 and Th17 cells in a Treg-dependent fashion. The findings indicate that mice-deficient for the HR (13R−/−) are more susceptible to experimental allergic encephalomyelitis than mice sufficient for the HR (13R+/+) and develop early onset and more severe disease. Moreover, Th17 cells from 13R−/− mice had reduced ability to convert to Th1 cells and displayed reduced sensitivity to suppression by Tregs relative to Th17 effectors from 13R+/+ mice. These observations suggest that IL-4 and IL-13 likely operate through the HR and influence Th17 cells to convert to Th1 cells and to acquire increased sensitivity to suppression, leading to control of immune-mediated CNS inflammation. These previously unrecognized findings shed light on the intricacies underlying the contribution of cytokines to peripheral tolerance and control of autoimmunity.
Influence of static alternating field demagnetization on anisotropy of magnetic susceptibility: Experiments and implications
Authors: Biedermann Andrea R. , Jackson Mike , Bilardello Dario , Feinberg Joshua M. , Brown Maxwell C. , McEnroe Suzanne A. 
Published: August 2017

AbstractAnisotropy of magnetic susceptibility (AMS) indicates the preferred orientation of a rock's constituent minerals. However, other factors can influence the AMS, e.g., domain wall pinning or domain alignment in ferromagnetic minerals. Therefore, it is controversial whether samples should be alternating field (AF) demagnetized prior to AMS characterization. This may remove the influence of natural remanent magnetization (NRM) or domain wall pinning on AMS; however, it may also result in field‐induced anisotropy. This study investigates the influence of stepwise AF and low‐temperature demagnetization on mean susceptibility, principal susceptibility directions, AMS degree and shape for sedimentary, metamorphic, and igneous rocks. Alternating fields up to 200 mT were applied along the sample x, y, and z axes, rotating the order for each step, to characterize the relationship between AMS principal directions and the last AF orientation. The changes in anisotropy, defined by the mean deviatoric susceptibility of the difference tensors, are between <2% and 270% of the AMS in NRM‐state. Variations in AMS parameters range from small changes in shape to complete reorientation of principal susceptibility axes, with the maximum susceptibility becoming parallel to the last AF direction. This is most prevalent in samples with low degrees of anisotropy in the NRM‐state. No clear correlations were found between field‐induced anisotropy and hysteresis properties. Therefore, we propose that future studies check any samples whose AMS is carried by ferromagnetic minerals and low anisotropy degrees for AF‐induced artifacts. These results highlight the need for understanding the AMS sources and carriers prior to any structural interpretation.
Trace element partitioning between plagioclase and melt: An investigation of the impact of experimental and analytical procedures
Authors: Nielsen Roger L. , Ustunisik Gokce , Weinsteiger Allison B. , Tepley Frank J. , Johnston A. Dana , Kent Adam J. R. 
Published: August 2017

AbstractQuantitative models of petrologic processes require accurate partition coefficients. Our ability to obtain accurate partition coefficients is constrained by their dependence on pressure temperature and composition, and on the experimental and analytical techniques we apply. The source and magnitude of error in experimental studies of trace element partitioning may go unrecognized if one examines only the processed published data. The most important sources of error are relict crystals, and analyses of more than one phase in the analytical volume. Because we have typically published averaged data, identification of compromised data is difficult if not impossible. We addressed this problem by examining unprocessed data from plagioclase/melt partitioning experiments, by comparing models based on that data with existing partitioning models, and evaluated the degree to which the partitioning models are dependent on the calibration data. We found that partitioning models are dependent on the calibration data in ways that result in erroneous model values, and that the error will be systematic and dependent on the value of the partition coefficient. In effect, use of different calibration datasets will result in partitioning models whose results are systematically biased, and that one can arrive at different and conflicting conclusions depending on how a model is calibrated, defeating the purpose of applying the models. Ultimately this is an experimental data problem, which can be solved if we publish individual analyses (not averages) or use a projection method wherein we use an independent compositional constraint to identify and estimate the uncontaminated composition of each phase.
Mechanical behavior, failure mode, and transport properties in a porous carbonate
Authors: Baud Patrick , Exner Ulrike , Lommatzsch Marco , Reuschlé Thierry , Wong Teng‐fong 
Published: August 2017

AbstractWe performed a systematic investigation of mechanical compaction, strain localization, and permeability in Leitha limestone. This carbonate from the area of Vienna (Austria) occurs with a broad range of grain sizes and porosity, due to changes in depositional regime and degree of cementation. Our new mechanical data revealed a simple relation between porosity and mechanical strength in both the brittle and ductile regimes. Increasing cementation and decreasing porosity led to a significant increase of the rock strength in both regimes. Micromechanical modeling showed that the dominant micromechanisms of inelastic deformation in Leitha limestone are pore‐emanated microcracking in the brittle regime, and grain crushing and cataclastic pore collapse in the ductile regime. Microstructural analysis and X‐ray computed tomography revealed the development of compaction bands in some of the less cemented samples, while more cemented end‐members failed by cataclastic flow in the compactant regime. In contrast to mechanical strength, permeability of Leitha limestone was not significantly impacted by increasing cementation and decreasing porosity. Our microstructural and tomography data showed that this was essentially due to the existence of a backbone of connected large macropores in all our samples, which also explained the relatively high permeability (in the range of 2–5 darcies) of Leitha limestone in comparison to other carbonates with significant proportion of micropores.
Optical Response From Functionalized Atomically Thin Nanomaterials
Authors: Malic Ermin , Berghäuser Gunnar , Feierabend Maja , Knorr Andreas 
Published: August 2017

AbstractChemical functionalization of atomically thin nanostructures presents a promising strategy to create new hybrid nanomaterials with remarkable and externally controllable properties. Here, we review our research in the field of theoretical modeling of carbon nanotubes, graphene, and transition metal dichalcogenides located in molecular dipole fields. In particular, we provide a microscopic view on the change of the optical response of these technologically promising nanomaterials due to the presence of photo‐active spiropyran molecules. The feature article presents a review of recent theoretical work providing microscopic view on the optical response of chemically functionalized carbon nanotubes, graphene, and monolayered transition metal dichalcogenides. In particular, we propose a novel sensor mechanism based on the molecule‐induced activation of dark excitons. This results in a pronounced additional peak presenting an unambiguous optical fingerprint for the attached molecules.
Molecular Recognition‐Mediated Transformation of Single‐Chain Polymer Nanoparticles into Crosslinked Polymer Films
Authors: Mahon Clare S. , McGurk Christopher J. , Watson Scott M. D. , Fascione Martin A. , Sakonsinsiri Chadamas , Turnbull W. Bruce , Fulton David A. 
Published: August 2017

AbstractWe describe single‐chain polymer nanoparticles (SCNPs) possessing intramolecular dynamic covalent crosslinks that can transform into polymer films through a molecular recognition‐mediated crosslinking process. The SCNPs utilise molecular recognition with surface‐immobilised proteins to concentrate upon a substrate, bringing the SCNPs into close spatial proximity with one another and allowing their dynamic covalent crosslinkers to undergo intra‐ to interpolymer chain crosslinking leading to the formation of polymeric film. SCNPs must possess both the capacity for specific molecular recognition and a dynamic nature to their intramolecular crosslinkers to form polymer films, and an investigation of the initial phase of film formation indicates it proceeds from features which form upon the surface then grow predominantly in the xy directions. This approach to polymer film formation presents a potential method to “wrap” surfaces displaying molecular recognition motifs—which could potentially include viral, cellular and bacterial surfaces or artificial surfaces displaying multivalent recognition motifs—within a layer of polymer film.
Polymer/boehmite nanocomposites: A review
Authors: Karger‐Kocsis József , Lendvai László 
Published: August 2017

ABSTRACTBoehmite is an aluminum oxyhydroxide [AlO(OH)] which is preferentially used as precursor for the production of (transition) aluminum oxides. Boehmite alumina (BA) nanoparticles are available in various morphologies due to versatile synthesis routes, which are briefly introduced. The peripheral hydroxyl groups of BA offer manifold functionalization possibilities for tailoring the dispersion and filler/matrix adhesion properties. The incorporation of BA nanofillers, with and without surface treatments, may yield improved mechanical and novel functional properties in polymers. BA can be introduced in polymers and polymer composites through different methods. This comprehensive overview covers the basic results reported on polymer/BA nanocomposites in the open literature. In this review, polymer matrices are grouped into thermoplastics, thermosets, and rubbers. Using literature results and our own findings, we have identified promising R&D trends with polymer/BA nanocomposites. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45573.
Pacinian Corpuscles in Human Lymph Nodes
Authors: Feito J. , Cobo J.L. , Santos‐Briz A. , Vega J.A. 
Published: August 2017

ABSTRACTThe occurrence of Pacinian corpuscles associated to lymph nodes is an anatomical rarity and very scarce information exists in this regard. Here we examined immunohistochemically four Pacinian corpuscles found in the close vicinity of the hiliar blood vessels of lymph nodes (2 cervical, 1 axillary, and 1 inguinal) during routine surgical pathology. Pacinian corpuscles were normally arranged and displayed a pattern of protein distribution as follows: the axon was positive for neurofilament proteins and neuron specific enolase, the inner core cells showed intense S100 protein and vimentin immunostaining while they were negative for glial fibrillary acidic protein, type IV collagen and glucose transporter 1; vimentin, type IV collagen, and glucose transporter 1 were also observed also in the outer‐core and the capsule. These results are in agreement with those reported for cutaneous Pacinian corpuscles, demonstrating that the immunohistochemical profile of these corpuscles is independent of its anatomical localization. The possible functional significance of Pacinian corpuscles in lymph nodes is discussed. Anat Rec, 300:2233–2238, 2017. © 2017 Wiley Periodicals, Inc.
Role of Stromelysin 2 (Matrix Metalloproteinase 10) as a Novel Mediator of Vascular Remodeling Underlying Pulmonary Hypertension Associated With Systemic Sclerosis
Authors: Avouac Jérôme , Guignabert Christophe , Hoffmann‐Vold Anna Maria , Ruiz Barbara , Dorfmuller Peter , Pezet Sonia , Amar Olivia , Tu Ly , Van Wassenhove Jérôme , Sadoine Jérémy , Launay David , Elhai Muriel , Cauvet Anne , Subramaniam Arun , Resnick Robert , Hachulla Eric , Molberg Øyvind , Kahan André , Humbert Marc , Allanore Yannick 
Published: August 2017

ObjectiveTo elucidate the role of gene candidates involved in pulmonary hypertension (PH) associated with systemic sclerosis (SSc).MethodsGene candidates were identified through microarray experiments performed on Affymetrix GeneChip Human Exon 1.0 ST arrays in endothelial progenitor cell (EPC)–derived endothelial cells (ECs) obtained from patients with SSc‐associated PH, patients with SSc without PH, and healthy control subjects. Expression of identified gene candidates was assessed by quantitative sandwich enzyme‐linked immunosorbent assay in the serum, and by immunohistochemistry in lesional lung tissue. The functional importance of the identified gene candidates was then evaluated in fos‐related antigen 2–transgenic (Fra‐2–Tg) mice that spontaneously develop SSc‐like features associated with an intense pulmonary vascular remodeling.ResultsMicroarray experiments revealed that the matrix metalloproteinase 10 (MMP‐10) gene was the top up‐regulated gene in SSc‐associated PH EPC‐derived ECs. Circulating serum proMMP10 concentrations were markedly increased in patients with SSc‐associated PH compared to SSc patients without PH and healthy controls. Consistent with these observations, a strong MMP10 staining of the thickened wall of distal pulmonary arteries was found both in the lungs of patients with SSc‐associated PH and in the lungs of Fra‐2–Tg mice. Daily treatment of Fra‐2–Tg mice with neutralizing anti‐MMP10 antibodies did not significantly affect the development and severity of pulmonary fibrosis, but did reverse established PH and markedly reduced pulmonary vascular remodeling by reducing cell proliferation, cell survival, and the platelet‐derived growth factor signaling axis.ConclusionGene expression profiling of EPC‐derived ECs identified MMP10 as a novel candidate gene in SSc‐associated PH. MMP10 is overexpressed in the serum and pulmonary arteries of patients with SSc‐associated PH, and its blockade alleviates PH in the Fra‐2–Tg mouse model. MMP10 appears to be a prospective treatment target for this devastating disorder.