bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modular tapered titanium stems in revision arthroplasty of the hip
Authors: Konan S. , Garbuz D. S. , Masri B. A. , Duncan C. P. 
Published: January 2016

Tapered fluted titanium stems are increasingly used for femoral revision arthroplasty. They are available in modular and non-modular forms. Modularity has advantages when the bone loss is severe, the proximal femur is mis shapen or the surgeon is unfamiliar with the implant, but it introduces the risk of fracture of the stem at the junction between it and the proximal body segment. For that reason, and while awaiting intermediate-term results of more recently introduced designs of this junction, non-modularity has attracted attention, at least for straightforward revision cases. We review the risks and causes of fracture of tapered titanium modular revision stems and present an argument in favour of the more selective use of modular designs. Cite this article: Bone Joint J 2016;98-B(1 Suppl A):50–3.
Systemic cobalt toxicity from total hip arthroplasties
Authors: Zywiel M. G. , Cherian J. J. , Banerjee S. , Cheung A. C. , Wong F. , Butany J. , Gilbert C. , Overgaard C. , Syed K. , Jacobs J. J. , Mont M. A. 
Published: January 2016

As adverse events related to metal on metal hip arthroplasty have been better understood, there has been increased interest in toxicity related to the high circulating levels of cobalt ions. However, distinguishing true toxicity from benign elevations in cobalt levels can be challenging. The purpose of this review is to examine the use of cobalt alloys in total hip arthroplasty, to review the methods of measuring circulating cobalt levels, to define a level of cobalt which is considered pathological and to review the pathophysiology, risk factors and treatment of cobalt toxicity. To the best of our knowledge, there are 18 published cases where cobalt metal ion toxicity has been attributed to the use of cobalt-chromium alloys in hip arthroplasty. Of these cases, the great majority reported systemic toxic reactions at serum cobalt levels more than 100 μg/L. This review highlights some of the clinical features of cobalt toxicity, with the goal that early awareness may decrease the risk factors for the development of cobalt toxicity and/or reduce its severity. Take home message: Severe adverse events can arise from the release of cobalt from metal-on-metal arthroplasties, and as such, orthopaedic surgeons should not only be aware of the presenting problems, but also have the knowledge to treat appropriately. Cite this article: Bone Joint J 2016;98-B:14–20.
Which imaging modality is most effective for identifying pseudotumours in metal-on-metal hip resurfacings requiring revision
Authors: Matharu G. S. , Mansour R. , Dada O. , Ostlere S. , Pandit H. G. , Murray D. W. 
Published: January 2016

Aims The aims of this study were to compare the diagnostic test characteristics of ultrasound alone, metal artefact reduction sequence MRI (MARS-MRI) alone, and ultrasound combined with MARS-MRI for identifying intra-operative pseudotumours in metal-on-metal hip resurfacing (MoMHR) patients undergoing revision surgery. Methods This retrospective diagnostic accuracy study involved 39 patients (40 MoMHRs). The time between imaging modalities was a mean of 14.6 days (0 to 90), with imaging performed at a mean of 5.3 months (0.06 to 12) before revision. The prevalence of intra-operative pseudotumours was 82.5% (n = 33). Results Agreement with the intra-operative findings was 82.5% (n = 33) for ultrasound alone, 87.5% (n = 35) for MARS-MRI alone, and 92.5% (n = 37) for ultrasound and MARS-MRI combined. The diagnostic characteristics for ultrasound alone and MARS-MRI alone reached similar sensitivities (90.9% vs 93.9%) and positive predictive values (PPVs; 88.2% vs 91.2%), but higher specificities (57.1% vs 42.9%) and negative predictive values (NPVs; 66.7% vs 50.0%) were achieved with MARS-MRI. Ultrasound and MARS-MRI combined produced 100% sensitivity and 100% NPV, whilst maintaining both specificity (57.1%) and PPV (91.7%). For the identification of a pseudotumour, which was confirmed at revision surgery, agreement was substantial for ultrasound and MARS-MRI combined (κ = 0.69), moderate for MARS-MRI alone (κ = 0.54), and fair for ultrasound alone (κ = 0.36). Discussion These findings suggest that ultrasound and/or MARS-MRI have a role when assessing patients with a MoMHR, with the choice dependent on local financial constraints and the availability of ultrasound expertise. However in patients with a MoMHR who require revision, combined imaging was most effective. Take home message: Combined imaging with ultrasound and MARS-MRI always identified intra-operative pseudotumours if present. Furthermore, if neither imaging modality showed a pseudotumour, one was not found intra-operatively. Cite this article: Bone Joint J 2016;98-B:40–8.
The supply and demand functions for Turkey’s manufacturing industry: Simultaneous equation systems<p>Türkiye’nin imalat sanayi ihracat ve ithalatının talep ve arz fonksiyonu: Eşanlı denklem modeli
Authors: Önder Kübra , Akın Büşra 
Published: January 2016

<p>Foreign trade policies applied to achieve economic growth and structural changes in the economies have an important role. The applications of these policies to determination of the direction, composition, and volume of exports and imports have affected on the price and income elasticities of exported and imported goods. Therefore, the export and the import policies must be analyzed with regards to the price and income elasticities. Considering the studies done so far, econometric analysis of supply and demand functions of export and import are generally seen analyzed based on a single equation model. Also simultaneous relationship between the supply and demand is mostly ignored. For this reason, the major aim of this study is to examine the simultaneous relationship between the supply and demand functions of export and import of manufacturing industry by using Two Stage Least Squares Method. According to results of estimation income and price elasticities for supply and demand of import are found compatible with the theory. Both in export and import demand equation of manufacturing, income and price elasticities are found positive and negative respectively. And also export and import supply elasticities for manufacturing are compatible with the theoretical expectations.</p><p> </p><p><strong>Özet</strong></p><p><strong></strong>Ekonominin büyümesi ve yapısal değişiminde, dış ticaret politikalarının önemli bir yeri vardır. İhracat ve ithalatın yönü, hacmi ve kompozisyonunu belirlemek amacıyla alınan kararlar, malların fiyat ve gelir esnekliklerine etkide bulunmaktadır. Bu nedenle bir ülkenin ihracat ve ithalat rejimi incelenirken, fiyat ve gelir esneklikleri de dikkate alınmalıdır. Bugüne kadar yapılan çalışmalar gözden geçirildiğinde, genellikle ihracat ve ithalat arz ve talep fonksiyonlarının ekonometrik analizinin tek denklemli model temel alınarak incelendiği görülmektedir. İhracat arz ve talep fonksiyonları arasındaki eşanlı gelir ve fiyat ilişkisi çoğunlukla göz ardı edilmektedir. Bu nedenle bu çalışmanın temel amacı; ihracat arz ve ithalat talep fonksiyonları arasındaki eşanlılık ilişkisini imalat sanayi özelinde, eşanlı denklem sistemlerinden iki aşamalı en küçük kareler yöntemi kullanarak incelemektir. Tahmin sonuçlarına göre, imalat sanayi ithalat arz ve talebine ait gelir ve fiyat esneklikleri ile imalat sanayi ihracat talebine ait gelir ve fiyat esnekliği ve ihracat arz denklemine ait gelir ve fiyat esnekliklerinin işareti teoriyle uyumlu bulunmuştur. </p>
Misspecification in Mixed-Model-Based Association Analysis
Authors: Kruijer Willem 
Published: January 2016

Abstract
Additive genetic variance in natural populations is commonly estimated using mixed models, in which the covariance of the genetic effects is modeled by a genetic similarity matrix derived from a dense set of markers. An important but usually implicit assumption is that the presence of any nonadditive genetic effect increases only the residual variance and does not affect estimates of additive genetic variance. Here we show that this is true only for panels of unrelated individuals. In the case that there is genetic relatedness, the combination of population structure and epistatic interactions can lead to inflated estimates of additive genetic variance.
Medical Countermeasures for Children in Public Health Emergencies, Disasters, or Terrorism
Authors:   DISASTER PREPAREDNESS ADVISORY COUNCIL, Krug Steven E. , Chung Sarita , Fagbuyi Daniel B. , Fisher Margaret C. , Needle Scott M. , Schonfeld David J. 
Published: January 2016

This Policy Statement was reaffirmed May 2022.
Significant strides have been made over the past 10 to 15 years to develop medical countermeasures (MCMs) to address potential disaster hazards, including chemical, biological, radiologic, and nuclear threats. Significant and effective collaboration between the pediatric health community, including the American Academy of Pediatrics, and federal partners, such as the Office of the Assistant Secretary for Preparedness and Response, Centers for Disease Control and Prevention, Federal Emergency Management Agency, National Institutes of Health, Food and Drug Administration, and other federal agencies, over the past 5 years has resulted in substantial gains in addressing the needs of children related to disaster preparedness in general and MCMs in particular. Yet, major gaps still remain related to MCMs for children, a population highly vulnerable to the effects of exposure to such threats, because many vaccines and pharmaceuticals approved for use by adults as MCMs do not yet have pediatric formulations, dosing information, or safety information. As a result, the nation’s stockpiles and other caches (designated supply of MCMs) where pharmacotherapeutic and other MCMs are stored are less prepared to address the needs of children compared with those of adults in the event of a disaster. This policy statement provides recommendations to close the remaining gaps for the development and use of MCMs in children during public health emergencies or disasters. The progress made by federal agencies to date to address the needs of children and the shared commitment of collaboration that characterizes the current relationship between the pediatric health community and the federal agencies responsible for MCMs should encourage all child advocates to invest the necessary energy and resources now to complete the process of remedying the remaining significant gaps in preparedness.
VIETNAM - RUSSIAN COOPERATION INSTALLING AND TESTING THE TOMOGRAPHY ELECTRIC COMPLEX (TEC-2) FOR INVESTIGATION OF SHALLOW GEOLOGICAL ENVIRONMENT
Authors: Cuong Do Huy , Anh Bui Thi Bao , Nhan Nguyen Thi , Tung Nguyen Xuan , Hung Pham Duc , Thanh Nguyen Xuan 
Published: January 2016

The geophysical investigation system named TEC-2 (Tomography Electric Complex-2) was designed, installed and tested in Institute of Marine Geology and Geophysics. This TEC-2 is the scientific cooperation product of Geomagnetic and Geoelectric Department of and POI and Geo - environmental Department of IMGG-VAST. The test results using TEC-2 show the capability of investigating by using certain pole system, short investigation time, high stability, the accuracy of two investigation times being more than 92%. The distributed design of electric poles, measuring operation, parameter selection, … are programmed and controlled automatically by computer. The TEC-2 system was used for investigating the weak structures in islands of Song Tu Tay, Son Ca, Nam Yet and Sinh Ton in Truong Sa Archipelagos and shallow geological environment in the area of Red River bank in Son Tay Hanoi. The acquired data contributed to the success of the scientific projects managed by IMGG in the National Program of Bien Dong and islands in the period of 2011 - 2013 and VAST’s research project in the period of 2013 - 2014.
UTILIZAÇÃO DE ABACAXI PARA ELABORAÇÃO DE VINHOS: AVALIAÇÃO FISICO QUÍMICA E ACEITABILIDADE
Authors: Da Silva Jonas Luiz Almada , Dantas Dayene Louyse Lírio , Gaspareto Odisséia Carla Pires , Falcão Filho Ronaldo Dos Santos 
Published: January 2016

Vinho de frutas ou fermentado de frutas é a bebida com graduação alcoólica de quatro a quatorze por cento em volume, a vinte graus Celsius, obtida da fermentação alcoólica do mosto de fruta sã, fresca e madura. O presente trabalho teve como objetivo a elaboração de uma bebida alcoólica fermentada de abacaxi (vinho de abacaxi), caracterizando sob o ponto de vista físico-químico e sensorial o produto obtido. O experimento foi realizado com abacaxis da variedade Pérola, obtidos em comercio local da cidade de Currais Novos-RN. Os ensaios fermentativos foram realizados no laboratório de Alimentos do IFRN Campus Currais Novos por um período de vinte dias, em temperatura controlada onde, após este período realizaram-se as trasfegas e estabilização do vinho. O produto obtido foi submetido às análises de acidez total, cinzas, densidade, açúcares e grau alcoólico por ebuliometria, além da avaliação da aceitabilidade do produto. Os valores médios para acidez total, cinzas, densidade relativa, grau alcoólico e açúcares totais foram 87,09 mEq.L-1 ; 1,7 g.L-1; 0,9944 g.cm-3; 13% (v/v) e 3,0 g.L-1. As análises sensoriais demonstraram que, sobre o parâmetro sabor, não houve grande aceitação pelos provedores por se tratar de um vinho seco. Os parâmetros cor e odor foram bem aceitos pelos provadores. Com os resultados pode-se verificar a viabilidade de produção de vinho de abacaxi como uma alternativa de utilização do fruto e opção para o consumidor.
Palavras-chave: abacaxi, vinho, análises físico-químicas
Intervenciones de enfermería para disminuir la sobrecarga en cuidadores: un estudio piloto
Authors: Sánchez Martínez Rosa Tulia , Molina Cardona Edith Milena , Gómez-Ortega Olga Rocío 
Published: January 2016

<p><strong>Introducción: </strong>Los cuidadores informales,<strong> </strong>son personas<strong> </strong>familiares o no, que asumen el cuidado directo a una persona por voluntad, necesidad u obligación cultural, no reciben remuneración y se exponen a problemáticas debidas al contexto y desgaste que significa cuidar, convirtiéndose en sujetos de cuidados para el profesional de enfermería, requiriendo generar estrategias de acompañamiento y fortalecimiento para evitar la sobrecarga del cuidador. <strong>Materiales y Métodos:</strong> Estudio cuasi-experimental sin grupo control, con medición pre y post de las escalas de Zarit y APGAR familiar para evidenciar el efecto de las intervenciones de enfermería en el nivel de sobrecarga del cuidador derivadas de las necesidades de cuidado identificadas en la valoración previa de la diada cuidador-adulto mayor. <strong>Resultados:</strong> Muestra compuesta por diadas, el 88% de los cuidadores eran mujeres, edad media de 52± 16 años, dedicaban 24 horas al cuidado. El 100% de receptores de cuidado eran dependientes del cuidador. Las intervenciones, disminuyeron la sobrecarga percibida por los cuidadores. <strong>Discusión: </strong>El cuidado de enfermería brindado en otros espacios extra hospitalarios y centrados en personas no enfermas, contribuye a disminuir la sobrecarga requiriendo del apoyo permanente del profesional de enfermería. <strong>Conclusiones:</strong> Se evidenció la disminución de la sobrecarga de cuidadores y el aumento del grado de funcionalidad de las familias al medirlos después de realizar las intervenciones identificación rol de cuidador, autocuidado, estrategias para brindar cuidado con calidad, manejo de conflictos intrafamiliares, comunicación, relajación y habilidades de cuidado.</p><p><strong><em>Cómo citar este artículo:</em></strong><em> Sánchez RT, Molina EM, Gómez-Ortega OR</em><em>.</em> <em>Intervenciones de enfermería para disminuir la sobrecarga en cuidadores: un estudio piloto. </em><em>Rev Cuid. 201</em><em>6</em><em>; </em><em>7</em><em>(1): 1171-84.</em><em> </em><em><a href="http://dx.doi.org/10.15649/cuidarte.v7i1.251">http://dx.doi.org/10.15649/cuidarte.v7i1.251</a> </em></p>
GEOQUÍMICA E GEOCRONOLOGIA DE GRANITOS ANOROGÊNICOS TONIANOS (ca. 914–899 Ma) DA FAIXA ARAÇUAÍ NO SUL DO ESTADO DA BAHIA
Authors: Menezes Rita da Cunha Leal , Conceição Herbet , Rosa Maria de Lourdes da Silva , Macambira Moacir José Buenano , Galarza Marco Antonio , Rios Débora Correia 
Published: January 2016

Na região sul da Bahia, entre Itarantim e Potiraguá, identificou-se a ocorrência de cinco stocks elipsoidais de granito, alinhados na direção E-W, que são intrusivos no Complexo Itapetinga. Estes stocks são constituídos por biotita-hornblenda granito com termos sieníticos subordinados. Os granitos são metaluminosos a peraluminosos e têm atributos geoquímicos característicos de intrusões anorogênicas do tipo A1, tais como conteúdos de álcalis similares, altos valores de SiO2, Nb, Y, Ta, Th e Terras Raras Leves, baixos valores de CaO, Sr e Ba, e alta razão FeO*/MgO. Essas características são indicativas de magma riolítico com importante contribuição mantélica. Análises isotópicas Pb-Pb por evaporação de monocristais de zircão forneceram as idades de 914 ± 3 Ma (Bolívia), 911 ± 2 Ma (Irmão César), 907 ± 2 Ma (Jundiá), 905 ± 4 Ma (Monte Alto) e 899 ± 3 Ma (Serras) para os stocks estudados. Destaca-se que este magmatismo anorogênico do Toniano é cerca de 200 milhões de anos mais antigo do que a Província Alcalina do Sul do Estado da Bahia, originada no Criogeniano (730-690 Ma). Os dados aqui apresentados tornam ainda mais consistente o modelo de rifte, proposto na literatura, para explicar a presença deste tipo de magmatismo do Toniano, na extremidade nordeste da Faixa Araçuaí.Palavras-Chave: granito tipo A, Toniano, Faixa Araçuaí, Bahia ABSTRACT: GEOCHEMISTRY AND GEOCHRONOLOGY OF TONIAN (ca. 914-899 Ma) ANOROGENIC GRANITES OF THE ARAÇUAÍ BELT, SOUTHERN BAHIA STATE, BRAZIL. Five ellipsoidal granitic stocks form intrusions aligned in the E-W direction and hosted by the Itapetinga Complex in the Itarantim–Potiraguá region, southern Bahia State. These stocks mainly consist of biotite-hornblende granite and minor syenitic rocks. The granitic rocks are metaluminous to peraluminous and show geochemical attributes of A1 type granites, such as similar contents of alkaline elements, and high SiO2, Nb, Y, Ta, Th and Light Rare Earth Elements, as well as low CaO, Sr and Ba, and high FeO*/MgO ratios, that suggest rhyolitic magma with important mantle contribution. Single zircon Pb-Pb isotopic analysis yielded the ages of 914 ± 3 Ma (Bolívia), 911 ± 2 Ma (Irmão César), 907± 2 Ma (Jundiá), 905 ± 4 Ma (Monte Alto) and 899 ± 3 Ma (Serras) for the studied stocks. This magmatic episode is ca. 200 Ma older than the South Bahia Alkaline Province, formed in Cryogenian time (730-690 Ma). The presented data reinforce the rift model suggested in the literature to explain the Tonian A-type magmatism in the northeastern tip of the Araçuaí Belt.Keywords: A-type granite, Tonian, Araçuaí Belt, Bahia.
CONCENTRAÇÕES DE METAIS PESADOS EM SEDIMENTOS DO RIO SÃO FRANCISCO ENTRE TRÊS MARIAS E PIRAPORA-MG: GEOQUÍMICA E CLASSIFICAÇÃO DE RISCO AMBIENTAL
Authors: Trindade Wallace Magalhães , Horn Adolf Heinrich , Ribeiro Elizêne Veloso 
Published: January 2016

O objetivo deste trabalho é identificar áreas e fatores de risco de contaminação à biota a partir da análise da concentração e distribuição dos metais tóxicos (Zn, Cd, Pb, Cu, Cr e Ni) nos sedimentos do rio São Francisco entre Três Marias e Pirapora-MG. Na área de estudo, o uso e ocupação dos solos é caracterizado pelas atividades de beneficiamento de Zn e Pb em Três Marias, Fe-Si em Pirapora, e pelas atividades agrícolas, ambas apresentam aspectos físicos e químicos que comprometem a qualidade dos sedimentos. Para o desenvolvimento do trabalho, foram estabelecidas 59 estações de coleta, amostradas nas estações seca e úmida. As amostras de sedimentos foram submetidas a digestão parcial (HNO3) em microondas, conforme o método SW-846-3051–US EPA-1998. A quantificação dos metais feita por ICP-OES indicou concentrações elevadas para os elementos Zn (5974,16mg/kg), Pb (310,27mg/kg), Cu (81,40mg/kg) e Cd (34,89mg/kg) nos sedimentos amostrados na área urbano-industrial de Três Marias, representando alto risco de contaminação à biota.Palavras - chave: sedimentos, contaminação, metais tóxicos, risco ambiental, rio São Francisco. ABSTRACT: HEAVY METAL CONCENTRATIONS IN SEDIMENTS OF THE SÃO FRANCISCO RIVER BETWEEN TRES MARIAS AND PIRAPORA-MG: GEOCHEMISTRY AND CLASSIFICATION OF ENVIRONMENTAL RISK. This work aims to identify the areas and factors of biota contamination risk from analysis of toxic metals (Zn, Cd, Pb, Cu, Cr and Ni) concentration and distribution in sediments of the São Francisco River on the section between Três Marias and Pirapora-MG. On the area studied soils use and occupation is characterized by Zn and Pb manufacturing in Três Marias, Fe-Si and agricultural activities in Pirapora, presenting physic-chemical aspects which may affect sediment quality. In order to achieve the goals of this work, it was established 59 sample collecting points, collected during dry and wet seasons. Sediment samples were undertaken to partial digestion (HNO3) in microwave, according to SW-846-3051–US EPA -1998 method. Metal quantification done by ICP-OES pointed high concentrations for Zn (5974,16mg/kg), Pb (310,27mg/kg) Cu (81,40mg/kg) and Cd (34,89mg/kg) in sediments sampled in the section of the urban-industrial area of Três Marias, representing high risk of biota contamination.Keywords: sediments, contamination, toxic metals, environmental risk, São Francisco river
GEOLOGIA, PETROLOGIA E CONTEXTO GEOTECTÔNICO DOS GNAISSES E GRANITÓIDES DA REGIÃO DE COLATINA, ESPÍRITO SANTO
Authors: Uhlein Alexandre , Roncato Junior Jorge , Egydio-Silva Marcos , Parizek-Silva Yaro M. , Alves Michele 
Published: January 2016

região de Colatina, Estado do Espírito Santo, foi objeto de mapeamento geológico e detalhado estudo petrográfico e geoquímico visando reconhecer e caracterizar paragnaisses migmatíticos do Complexo Nova Venécia e granitóides sincolisionais do tipo S – Granitóide Colatina, que ocorrem no núcleo metamórfico-anatético do Orógeno Araçuaí. O Complexo Nova Venécia, é representado por paragnaisses migmatíticos, cujas relações de campo, dados de mineralogia, petrografia, geoquímica e geocronologia indicam que estas rochas foram, originalmente, sedimentos peraluminosos de composição grauvaquiana, depositados em possível bacia de retroarco. O Granitóide Colatina varia de monzogranitos a tonalitos, representando uma fusão anatética do tipo-S, ocorrida na fase sincolisional do Orógeno Araçuaí, mostrando uma persistente foliação concordante com a foliação regional. As relações do Granitóide Colatina com as rochas do Complexo Nova Venécia evidenciam que se trata de uma fusão autóctone.Palavras chave: Orógeno Araçuaí, núcleo metamórfico, granitóides. ABSTRACTGEOLOGY, PETROLOGY AND GEOTECTONIC CONTEXT OF GNEISSES AND GRANITOIDS OF THE COLATINA REGION, ESPIRITO SANTO, BRAZIL. The Colatina region, Espírito Santo state, Brazil, was the subject of detailed geological mapping and geochemical and petrographic study aiming to recognize and characterize the Nova Venécia Complex: migmatitic paragneisses, and S-type syncolisional granitoids – the Colatina Granitoid – occurring in the metamorphic core of the Araçuaí orogen. The Nova Venécia Complex is represented by migmatitic paragneiss, whose field relations and mineralogical, petrographical, geochemical and geochronological data indicate that these rocks were originally peraluminous sediments with wacke affinities, probably deposited in a retroarc basin. The Colatina Granitoids varies from monzogranites to tonalites, representing a S-type anatetic melt occurred during the syn-collisional event of the Araçuaí orogen, showing a persistent foliation concordant with the regional foliation. An authoctonous melt is interpreted from the relations between the Colatina Granitoids and the rocks from the Nova Venécia Complex.Keywords: Araçuaí orogen, metamorphic core, granitoids.