bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-Perceived Pre-Motor Symptoms Load in Patients with Parkinson’s Disease: A Retrospective Study
Authors: Rodríguez-Violante Mayela , de Saráchaga Adib Jorge , Cervantes-Arriaga Amin , Millán-Cepeda Roxanna , Leal-Ortega Roberto , Estrada-Bellmann Ingrid , Zuñiga-Ramírez Carlos 
Published: April 2016

Background: Parkinson’s disease is characterized by motor and non-motor clinical features. The latter may present as pre-motor symptoms several years before the motor onset. Objective: To analyze the association between pre-motor symptoms load and its lead-time in relation to the motor onset and time to diagnosis. Methods: A cross-sectional study was carried including subjects with Parkinson’s disease from five different movement disorders clinics in Mexico. A structured questionnaire was applied to assess the presence of six self-perceived pre-motor symptoms (hyposmia, depression, anxiety, constipation, pain and sleep disorders). Results: Overall frequency of pre-motor symptoms was 76.2% . Among the most prevalent symptoms were depression (38%), sleep disorders (37%) and anxiety (36.6%). The lead time to motor onset was greater for constipation (9.2±17.89 years) and pain (8.66±13.36 years). Patients with more than two pre-motor symptoms had a later age at motor onset when compared to patients without pre-motor symptoms (52.04±13.11 vs 56.55±12.97 years, p = 0.037). Late onset patients had a higher frequency of pre-motor symptoms (79% vs 65% in early onset, p = 0.002) and a higher load (1.75±1.37 vs 1.44±1.38, p = 0.033) in comparison to those with early onset. Female subjects reported a higher number of pre-motor symptoms (1.91±1.43 versus 1.48±1.29, p≤0.001). PIGD patients reported a greater frequency of pain (8%) compared to tremor (1%, p = 0.0064) and bradykinetic-rigid (0.61%, p = 0.0061). Anxiety lead-time was greater in tremor-dominant (10.83±15.77 years) compared to bradykinetic-rigid patients (3.48±12.56, p = 0.014). Conclusions: Pre-motor symptoms load is associated to a later motor onset of PD. Pre-motor symptoms are more frequent in subjects with late onset Parkinson’s disease. Female subjects report a higher number of pre-motor symptoms, depression and anxiety being the most common.
Risk Factor Profile in Parkinson’s Disease Subtype with REM Sleep Behavior Disorder
Authors: Jacobs Marie L. , Dauvilliers Yves , St. Louis Erik K. , McCarter Stuart J. , Romenets Silvia Rios , Pelletier Amélie , Cherif Mahmoud , Gagnon Jean-François , Postuma Ronald B. 
Published: April 2016

Background: Numerous large-scale studies have found diverse risk factors for Parkinson’s disease (PD), including caffeine non-use, non-smoking, head injury, pesticide exposure, and family history. These studies assessed risk factors for PD overall; however, PD is a heterogeneous condition. One of the strongest identifiers of prognosis and disease subtype is the co-occurrence of rapid eye movement sleep behavior disorder (RBD). In previous studies, idiopathic RBD was associated with a different risk factor profile from PD and dementia with Lewy bodies, suggesting that the PD-RBD subtype may also have a different risk factor profile. Objective: To define risk factors for PD in patients with or without associated RBD. Methods: In a questionnaire, we assessed risk factors for PD, including demographic, medical, environmental, and lifestyle variables of 189 PD patients with or without associated polysomnography-confirmed RBD. The risk profile of patients with vs. without RBD was assessed with logistic regression, adjusting for age, sex, and disease duration. Results: PD-RBD patients were more likely to have been a welder (OR = 3.11 (1.05–9.223), and to have been regular smokers (OR = 1.96 (1.04–3.68)). There were no differences in use of caffeine or alcohol, other occupations, pesticide exposure, rural living, or well water use. Patients with RBD had a higher prevalence of the combined family history of both dementia and parkinsonism (13.3% vs. 5.5% , OR = 3.28 (1.07–10.0). Conclusion: The RBD-specific subtype of PD may also have a different risk factor profile.
Checklist of British and Irish Hymenoptera - aculeates (Apoidea, Chrysidoidea and Vespoidea)
Authors: Else George , Bolton Barry , Broad Gavin 
Published: April 2016

The checklist of British and Irish aculeate Hymenoptera (Apoidea, Chrysidoidea and Vespoidea) is revised. Species distribution is summarised for all species at the level of country (England, Scotland, Wales, Ireland and Isle of Man).
The 601 native species represent an increase of 25 on the 1978 checklist, comprising mostly new discoveries. This increase is nearly balanced by the 23 species now presumed to be extinct in Britain and Ireland.
Les limites du protagonisme : une anthropologie politique de 1848
Authors: Traugott Mark , Boisson Hélène 
Published: April 2016

L’application aux événements de 1848 du concept de protagonisme introduit par Burstin se heurte au cadre temporel bien plus réduit et aux résultats équivoques de la révolution de Février. Pas un seul de ses principaux acteurs ne correspond pleinement au modèle que Burstin a si judicieusement dégagé pour 1789, ce qui s’explique en partie par le fait que la Grande Révolution et les décennies de troubles sociaux qui s’ensuivent ont radicalement transformé la conscience politique des générations ultérieures de militants. L’auteur met brièvement en parallèle le concept de protagonisme et la notion de « répertoire de contestation », pour proposer une réflexion sur la manière dont l’expérience de 1789 a pu faire évoluer en profondeur et une fois pour toutes les conditions de l’action révolutionnaire.
Raphaël et la question du corps
Authors: Dejardin Monique 
Published: April 2016

Résumé – L’adolescence est souvent une période difficile à traverser pour chaque enfant et pour ses parents qui ont oublié la leur, d’autant plus qu’elle n’est pas toujours « parlée » mais surtout agie. Raphaël a cumulé les handicaps a reconnu son père avant le début de sa prise en charge, lui qui ne parle pas vraiment. L’adolescence on réussit généralement à en sortir quand on est parvenu, en se cherchant, à intégrer la subjectivation.
Corps et spécificités des mécanismes de défense... de la famille obèse
Authors: Schwailbold Marie-Anne , Cuynet Patrice , Rosier Lise 
Published: April 2016

Notre étude investigue l’obésité à l’adolescence en replaçant ce symptôme dans une dynamique familiale. À travers la présentation d’une vignette clinique, cet article apporte un éclairage sur les mécanismes de défense à l’œuvre dans ces familles, permettant ainsi de fournir des pistes de compréhension à la résistance au traitement ainsi qu’aux rechutes. Nous proposons, à travers la projection de l’image inconsciente du corps familial dans différents médiateurs tels que l’arbre généalogique libre ou « génographie projective » et le dessin de la maison de rêve ou « spatiographie projective », le décryptage de ces mécanismes de défense, utilisés par les familles à obésité. Ils témoignent d’un fantasme groupal inconscient de vampirisme mutuel entre les membres.
CUTANEOUS HYPERPIGMENTATION IN MEGALOBLASTIC ANEMIA: A FIVE YEAR RETROSPECTIVE REVIEW.
Authors: Padhi Somanath , Sarangi RajLaxmi , Ramdas Anita , Ravichandran Kandasamy , Varghese Renu G’Boy , Alexander Thomas , Kurien George , Mookkappan Sudhagar 
Published: April 2016

Background: Cutaneous hyperpigmentation is an often overlooked clinical sign in megaloblastic anemia (MA) which has been sporadically reported in the literature.Methods: We describe the bone marrow (BM) changes and clinicolaboaratory characteristics of 25 of 198 adult cases (>16 years) with cutaneous hyperpigmentation who underwent BM evaluation for cytopenia (s).Results: Twenty-one of 25 cases (84%) had MA, while MA without hyperpigmentation occurred only in 12 of remainder 173 cases (P<0.001). Knuckle pad hyperpigmentation (KP) was noted in 16 (64%) cases; whereas 9 (36%) had diffuse brownish black discoloration (DP) of the palms and /or soles. Eighteen of 25 (72%) cases had pancytopenia (13 with KP) and 7 of 25 (28%) had bicytopenia (3 with KP). In addition, five cases (20%) presented with pyrexia of unknown origin. Of the 17 cases where data available, eleven were B12 deficient [<190 pg/ml; eight had severe deficiency (<100 pg/ml); ref.; 190-800pg/ml], while 4 had pure folate deficiency (< 4.0 ng/ml; ref.; 4-20ng/ml); and remainder 2 had combined B12 and folate deficiency. Compared to those with diffuse pigmentation; KP group had lower Hb (69.6 ± 24.2 vs. 86.3 ± 33.9 g/L), higher MCV (106.1 ±12.6 vs. 99.2 ± 7.6 fL), lower platelet count (50.9 ± 29.3 vs. 69.6 ± 36.5 x 109/L), and lower median B12 [100.0 (30.0 – 822.0) vs. 316.0 (142.0 – 1617.3) pg/ml] (P>0.05). In six cases where follow-up data were available, there was significant reversal of hyperpigmentation at 12 weeks following parenteral cobalamine therapy. In all five cases with pyrexia, fever subsided after 24 to 72 hours following administration of parenteral cobalamine therapy.Conclusion: Cutaneous hyperpigmentation, pyrexia, and cytopenia (s) are strongly associated with megaloblastic anemia. Knuckle pad hyperpigmentation is much more common than diffuse pigmentation of the palms and/or soles in such patents. A nonsignificant trend towards a greater degree of MA was found in cases with pigmentation of the knuckles.
Utilização de macrófitas aquáticas em substrato para a produção de mudas de moringa
Authors: Farias Walda Monteiro , Andrade Leonaldo Alves de , Albuquerque Manoel Bandeira de , Cunha João Rodrigues da 
Published: April 2016

A utilização de macrófitas aquáticas na composição de substratos para produção de mudas de moringa constitui uma alternativa sustentável. Portanto, objetivou-se com esta pesquisa avaliar o desenvolvimento de mudas de moringa, utilizando subtratos com macrófitas aquáticas, e determinar os teores de N, P e K nas mudas. Utilizaram-se diferentes combinações de macrófitas (M), esterco bovino (E) e terra vegetal (TV) para compor os subtratos. O experimento foi conduzido em esquema fatorial 3 × 4, em delineamento em blocos casualizados com quatro repetições. Foram avaliados: alturas das plantas, diâmetro da copa e caule, taxa relativa de crescimento em altura, em diâmetro da copa e do caule, matéria seca da parte aérea e raízes, comprimento de raízes e razão raízes/parte aérea, além dos teores de N, P e K das mudas. As mudas de moringa apresentam crescimento reduzido quando produzidas em substratos constituídos unicamente com taboa. Alface d’água e os substratos compostos por 60% M + 30% E + 10% TV e 70% M + 30% E, proporcionaram melhor nutrição e crescimento das mudas de moringa. O substrato 60M+30E+10TV composto pelo aguapé e taboa promoveram maior aporte de P para as mudas de moringa.Use of aquatic macrophytes in substrate composition to produce moringa The use of aquatic macrophytes in substrate composition to produce seedlings of moringa is a sustainable alternative. Therefore, the objective of this research was to evaluate the development of moringa seedlings using substrates composed with aquatic macrophytes, and to determine concentrations of N, P and K in the seedlings. We used different combinations of weeds (M), manure (E) and topsoil (TV) to compose the substrates. The experiment was conducted in a 3 × 4 factorial in randomized arrangement with four replications. We evaluated plant height, crown diameter and stem, relative growth rate in height, canopy diameter and in stem, dry matter of aerial part and of roots, root length and root/shoot ratio, besides the content of N, P and K in seedlings. Moringa seedlings showed reduced growth when produced in substrates composed only with cattail. Water lettuce and substrates composed of 60% M + 30%E + 10 % TV and 70% M + 30% E, promoted greater nutrition and growth of moringa seedlings. The substrate 60M +30E +10TV composed by water hyacinth and cattail resulted in greater amount of P in moringa seedlings.Index terms: Organic compound;Typha domingensis;Moringa oleifera
Procedência e adubação no crescimento inicial de mudas de cedro
Authors: Navroski Marcio Carlos , Tonett Erasmo Luis , Mazzo Marcos Vinicius , Frigotto Taciana , Pereira Mariane De Oliveira , Galvani Luan Vieira 
Published: April 2016

O objetivo do estudo foi avaliar o desenvolvimento inicial de diferentes procedências e a influência da adubação de base e cobertura no crescimento de mudas de Cedrela fissilis. Foram coletadas sementes de diferentes procedências nos municípios de Lapa, PR, Fernandes Pinheiro, PR e Itaara, RS. Após a germinação, as plântulas foram repicadas para sacos plásticos de 500 cm³, preenchidos com substrato comercial. Após 150 dias da repicagem avaliou-se altura total (h), diâmetro do colo (dc) e relação h/dc das mudas. Após as plântulas de Fernandes Pinheiro serem repicadas, avaliouse também o efeito da adubação de base (0, 2, 4, 6 e 8 g dm-3 de Osmocote®) e de cobertura (3 e 6 g L-1, respectivamente, de Peter’s® e ureia). A procedência e as doses do fertilizante de liberação controlada influenciaram no desenvolvimento inicial das mudas de Cedrela fissilis. A procedência de Itaara apresentou melhores resultados de crescimento das mudas. As mudas de cedro apresentam bom crescimento quando foi incorporado ao substrato 5 g dm-3 de Osmocote® e em adubação de cobertura 3 g L-1 de Peter’s®. A adubação de cobertura com ureia é pouco indicada para mudas de cedro.Provenances and fertilizer on early growth cedar seedlingsThe aim of the study was to evaluate the initial development of different provenances and the influence of base fertilizer and coverage on growth of Cedrela fissilis seedlings. Provenances of seeds were collected in Lapa, PR, Fernandes Pinheiro, PR and Itaara, RS. After germination, the seedlings were transplanted to plastic bags of 500 cm³, filled with commercial substrate. Total height (h), stem diameter (sd), and ratio h/sd seedlings were measured after 150 days of transplanting. Seedlings of Fernandes Pinheiro received basic fertilization after transplantation (0, 2, 4, 6 and 8 g dm-3 Osmocote®) and cover (3 and 6 g L-1, respectively, of Peter’s® and urea). The provenance and doses of controlled-release fertilizer influenced early development of Cedrela fissilis seedlings. Itaara provenance showed better seedlings growth. Cedar seedlings showed good growth when incorporated into the substrate 5 g dm-3 Osmocote® and, in addition, applied in topdressing 3 g L-1 of Peter’s®. Urea topdressing is rarely recommended for cedar seedlings.Index terms: Cedrella fissilis; Quality seedlings; Fertilizer controlled release
La villa del Dr. Müller en Praga y su autenticidad
Authors: Urlich Petr 
Published: April 2016

<p>Este artículo reúne un doble interés: en primer lugar relata el proceso de restauración de una obra singular de la época heroica del Movimiento Moderno, proceso que se ha basado en una metodología rigurosa y deliberada basada en el concepto de autenticidad; en segundo lugar desvela secretos hasta ahora soslayados sobre la propia concepción arquitectónica y espacial de Adolf Loos a través del análisis pormenorizado de su obra póstuma.</p>
Rehabilitación del Ayuntamiento de Morella (Castellón)
Authors: García Ros Vicente , Díaz Segura Alfonso 
Published: April 2016

<p>En este texto se elabora un recorrido por las circunstancias que rodearon a la intervención de recuperación del Ayuntamiento de Morella en Castellón, partiendo de sus condicionantes históricos y urbanos hasta sus soluciones en lenguaje contemporáneo para la rehabilitación de un espacio arquitectónico, con la intención de albergar con la dignidad requerida la función representativa de esta ciudad singular. Loggia desea con este artículo contribuir al conocimiento de esta ciudad monumental merecedora de <br />ser considerada patrimonio de la humanidad.</p>
Centro histórico de La Habana: intervención, recuperación y transformación
Authors: Delgado Martínez Michel 
Published: April 2016

<p>Este trabajo tiene como fin exponer la situación actual del patrimonio arquitectónico en el Centro Histórico de La Habana y algunas de las vías de solución que se están llevando a cabo para su recuperación. Se explicarán dos casos de estudio, la Plaza Vieja y el Parque Central, sitios de extraordinarios valores arquitectónicos e históricos.</p>
Óvila, setenta años después (de su expolio)
Authors: Merino de Cáceres José Miguel 
Published: April 2016

<p>Los agitados avatares del Monasterio cisterciense de Óvila, que fue comprado a piezas y trasladado a Estados Unidos para formar parte de una colección privada de un magnate norteamericano, sirven de excusa para una aguda reflexión sobre el triste destino de muchos monumentos españoles. El monasterio, desarticulado y almacenado en cajas, nunca se reconstruyó. Sólo en la actualidad, el trajín de este monasterio parece llegar a su fin, puesto que se han comenzado las labores de anastilosis en tierras americanas a cargo de un grupo de expertos, de los que forma parte relevante el autor de este sorprendente relato.</p>
La restauración de la arquitectura: cómo y por qué
Authors: Torsello Paolo B. 
Published: April 2016

<p>En un alarde de extraordinaria claridad mental, el autor analiza el concepto de restauración desde sus presupuestos de partida, entendiendo la arquitectura concebida como artificio creado por el hombre, portadora de memoria y sujeta al paso del tiempo. El proyecto de restauración implica la introducción de un acto de voluntad entre muchas opciones posibles que debe velar por la pervivencia, la integridad y la refuncionalización de la obra, una triada en un comprometido ejercicio de equilibrio que implica el cumplimiento conjunto y equilibrado de sus tres componentes.</p>
La restauración de los Baños del Almirante de Valencia
Authors: Camps García Concha , Esteban Chapapría Julián 
Published: April 2016

<p>El proceso de restauraciones contradictorias seguido desde hace décadas en los Baños del Almirante se ha reconducido finalmente en los últimos años en los que, partiendo de una realidad compleja, se ha llevado a cabo una metódica puesta en valor, asumiendo decisiones comprometidas, cuyos criterios se hacen explícitos en el presente artículo. Estas últimas investigaciones sobre los Baños del Almirante han aportado datos inéditos, como su origen cristiano medieval que desmiente la cronología islámica tradicionalmente establecida.</p>
La conservación de la piedra del Claustro de la Catedral de Oviedo
Authors: Rojo Araceli , Esbert Rosa Mª , Valdeón Luis , Alonso F. Javier , Mateos Félix , Ordaz Jorge 
Published: April 2016

<p>La intervención descrita en este artículo constituye un modelo metodológico para actuaciones similares de conservación de la piedra en edificios históricos por su rigor científico en el análisis y la evaluación, ponderación y confrontación de las opciones ofrecidas por el mercado en modo de controlar, dirigir y matizar la tecnología disponible, eligiendo las opciones más idóneas en cada caso, hacia una restauración consciente que controle la técnica, frente a la opción habitual que ve entregar la restauración a las riendas ciegas de la técnica.</p>
The Influence of Dental Shade Guides and Experience on the Accuracy of Shade Matching
Authors: Nakhaei Mohammadreza , Ghanbarzadeh Jalil , Alavi Samin , Amirinejad Sahar , Rajatihaghi Hamidreza 
Published: April 2016

ABSTRACT

Aim
There is limited and inconsistent information on some factors affecting visual shade selection. The aim of this study was to evaluate the influence of shade guide type and professional experience on shade-matching results.

Materials and methods
Thirty Dental students (DS), 30 General dentists (GDs) and 30 Dental specialists (S) participated in this study. The participants were asked to match six target tabs using two dental shade guides: Vitapan Classical (VC) and Vitapan 3D-Master (3D). An intraoral spectrophotometer was used for color measurement of target tabs and selected tabs. The color difference (Conflict of interest: NoneE) values between the target tab and selected tab were calculated. Data were analyzed using analysis of variance (ANOVA) and paired t-test (α = 0.05). Results of the first five best matches for each target tab were expressed as ΔE1 to ΔE5. Differences in the mean values of ΔE1 to ΔE5 between VC and 3D were compared using descriptive statistics.

Results
There were no significant differences among the three participating groups in ΔE values when the 3D was used (p = 0.389). However, significant differences were found with VC (p < 0.001). The ΔE values achieved from the 3D were significantly lower than those from VC for DS and S (p = 0.001 and p < 0.001, respectively). For each of the first five best matches, the mean ΔE values from the 3D were smaller than the corresponding values of VC.

Conclusion
The type of dental shade guide affected the shadematching results. The level of experience was not found to be an influential factor in shade matching when 3D-Master shade guide was used.

Clinical significance
Compared with Vitapan Classical shade guide, use of the Vitapan 3D-Master shade guide improves shade-matching results.

How to cite this article
Nakhaei M, Ghanbarzadeh J, Amirinejad S, Alavi S, Rajatihaghi H. The Influence of Dental Shade Guides and Experience on the Accuracy of Shade Matching. J Contemp Dent Pract 2016;17(1):22-26.
Variability of water vapour in the Arctic stratosphere
Authors: Thölix Laura , Backman Leif , Kivi Rigel , Karpechko Alexey Yu. 
Published: April 2016

Abstract. This study evaluates the stratospheric water vapour distribution and variability in the Arctic. A FinROSE chemistry transport model simulation covering the years 1990–2014 is compared to observations (satellite and frost point hygrometer soundings), and the sources of stratospheric water vapour are studied. In the simulations, the Arctic water vapour shows decadal variability with a magnitude of 0.8 ppm. Both observations and the simulations show an increase in the water vapour concentration in the Arctic stratosphere after the year 2006, but around 2012 the concentration started to decrease. Model calculations suggest that this increase in water vapour is mostly explained by transport-related processes, while the photochemically produced water vapour plays a relatively smaller role. The increase in water vapour in the presence of the low winter temperatures in the Arctic stratosphere led to more frequent occurrence of ice polar stratospheric clouds (PSCs) in the Arctic vortex. We perform a case study of ice PSC formation focusing on January 2010 when the polar vortex was unusually cold and allowed large-scale formation of PSCs. At the same time a large-scale persistent dehydration was observed. Ice PSCs and dehydration observed at Sodankylä with accurate water vapour soundings in January and February 2010 during the LAPBIAT (Lapland Atmosphere–Biosphere facility) atmospheric measurement campaign were well reproduced by the model. In particular, both the observed and simulated decrease in water vapour in the dehydration layer was up to 1.5 ppm.