bluuebunny/crossref_metadata_2025_split huggingface dataset:
ОСОБЛИВОСТІ ПРОВЕДЕННЯ ЛЕКЦІЙНИХ ЗАНЯТЬ З РОЗДІЛУ “ЗАХВОРЮВАННЯ СЛИЗОВОЇ ОБОЛОНКИ РОТОВОЇ ПОРОЖНИНИ” ДЛЯ СТУДЕНТІВ-ІНОЗЕМЦІВ
Authors: Sukhovolets I. O. 
Published: November 2016

У даній статті описані особливості проведення лекційних занять з розділу “Захворювання слизової оболонки ротової порожнини” для студентів-іноземців стоматологічного факультету. Описано й обґрунтовано переваги використання мультимедійних технологій та запропоновано методику проведення лекцій, яка сприятиме підвищенню концентрації студентів на матеріалі та кращому його запам’ятовуванню.
ПЕРЕДУМОВИ, ЗАВДАННЯ І ФОРМИ РАДЯНІЗАЦІЇ ОСВІТИ НА ТЕРНОПІЛЬЩИНІ У ВЕРЕСНІ 1939 – ЧЕРВНІ 1941 РОКУ
Authors: Kadobnyi T. B. , Kravchuk L. O. , Melnykova K. M. 
Published: November 2016

У пропонованій статті висвітлено механізми впровадження радянських освітньо-культурних цінностей, які відображали марксистсько-ленінську ідеологію, що ґрунтувалася на інтернаціональному світобаченні класових протиріч та постійній боротьбі з приватною власністю, руйнуючи релігійні переконання місцевого населення. Так звана реформа протирічила природі українського національного світогляду, нищила його культурно-освітні багатовікові надбання. З цією метою радянська влада запроваджувала в усіх західноукраїнських школах другу російську мову, як засіб міжнаціонального спілкування, а також освітню виховну мережу краю підпорядковувала єдиному Московському освітньо-методичному центру.
Concessive Participles and Epitactic Constructions in Ancient Greek
Authors: Jiménez Delgado José Miguel 
Published: November 2016

The purpose of this paper is to explain the construction of concessive participles introduced by kaì taûta in Ancient Greek as an instance of epitaxis, a specific type of coordination. This construction will be differentiated from the concessive participles introduced by adverbial kaí, the usual construction, by its syntactic configuration and pragmatics. The data is drawn from the works of Xenophon of Athens (c. 430–354 BC).
A Thickness-Weighted Average Perspective of Force Balance in an Idealized Circumpolar Current
Authors: Ringler Todd , Saenz Juan A. , Wolfram Phillip J. , Van Roekel Luke 
Published: November 2016

AbstractThe exact, three-dimensional, thickness-weighted averaged (TWA) Boussinesq equations are used to diagnose eddy–mean flow interaction in an idealized circumpolar current (ICC). The force exerted by mesoscale eddies on the TWA velocity is expressed as the divergence of the Eliassen–Palm flux tensor. Consistent with previous findings, the analysis indicates that the dynamically relevant definition of the ocean surface layer is composed of the set of buoyancy coordinates that ever reside at the ocean surface at a given horizontal position. The surface layer is found to be a physically distinct object with a diabatic and force balance that is largely isolated from the underlying adiabatic region in the interior. Within the ICC surface layer, the TWA meridional velocity is southward/northward in the top/bottom half and has a value near zero at the bottom. In the top half of the surface layer, the zonal forces due to wind stress and meridional advection of potential vorticity act to accelerate the TWA zonal velocity; equilibrium is obtained by eddies decelerating the zonal flow via a downward flux of eastward momentum that increases with depth. In the bottom half of the surface layer, the accelerating force of the wind stress is balanced by the eddy force and meridional advection of potential vorticity. The bottom of the surface layer coincides with the location where the zonal eddy force, meridional advection of potential vorticity, and zonal wind stress force are all zero. The net meridional transport Sf within the surface layer is a small residual of its southward and northward TWA meridional flows. The mean meridional gradient of the surface layer buoyancy is advected by Sf to balance the surface buoyancy flux.
Stimulated Imbalance and the Enhancement of Eddy Kinetic Energy Dissipation by Internal Waves
Authors: Barkan Roy , Winters Kraig B. , McWilliams James C. 
Published: November 2016

AbstractThe effects of internal waves (IWs), externally forced by high-frequency wind, on energy pathways are studied in submesoscale-resolving numerical simulations of an idealized wind-driven channel flow. Two processes are examined: the direct extraction of mesoscale energy by externally forced IWs followed by an IW forward energy cascade to dissipation and stimulated imbalance, a mechanism through which externally forced IWs trigger a forward mesoscale to submesoscale energy cascade to dissipation. This study finds that the frequency and wavenumber spectral slopes are shallower in solutions with high-frequency forcing compared to solutions without and that the volume-averaged interior kinetic energy dissipation rate increases tenfold. The ratio between the enhanced dissipation rate and the added high-frequency wind work is 1.3, demonstrating the significance of the IW-mediated forward cascades. Temporal-scale analysis of energy exchanges among low- (mesoscale), intermediate- (submesoscale), and high-frequency (IW) bands shows a corresponding increase in kinetic energy Ek and available potential energy APE transfers from mesoscales to submesoscales (stimulated imbalance) and mesoscales to IWs (direct extraction). Two direct extraction routes are identified: a mesoscale to IW Ek transfer and a mesoscale to IW APE transfer followed by an IW APE to IW Ek conversion. Spatial-scale analysis of eddy–IW interaction in solutions with high-frequency forcing shows an equivalent increase in forward Ek and APE transfers inside both anticyclones and cyclones.
Effects of a change in entry-to-practice criteria for cardiovascular perfusion in Canada: results of a national survey
Authors: Belway Dean , Tran Diem T.T. , Rubens Fraser D. 
Published: November 2016

Introduction: Years of experience and level of education are two important determinants of a clinician’s expertise. While entry-to-practice criteria for admission to perfusion training in Canada changed from clinical experience-based criteria to education-based criteria in 2006, the effects of these changes have not been studied. Objective: To determine the academic and clinical backgrounds of perfusionists in Canada, ascertain perceptions about the adequacy of training and evaluate the effects of the changes on the composition of the perfusion community of Canada. Methods: An electronic questionnaire was distributed to all practicing perfusionists in Canada, addressing details regarding clinical experience, academic education and perceptions about the adequacy of training. Results: Two hundred and twenty-eight questionnaires were completed, representing a 72% response rate. Perfusionists admitted under academic-based criteria have significantly higher levels of education (100% degree holders vs 69.1%, p<0.001), but less antecedent clinical training and experience (median, IQR: 0, 0 – 4.5 years vs 2, 2 – 8 years, p<0.0001), are younger (median age range 31-35 years vs 51-55 years, p<0.0001), more likely to be female (58.7% vs 41.3%, p=0.006) and are significantly more likely to enter perfusion because of attraction to the type of work (p=0.045). Many perfusionists (70, 32%) in Canada believe themselves inadequately trained for their clinical assignments outside the OR. In addition, 19% of perfusionists plan to retire over the next 10 years. Conclusions: The introduction of education-based entry criteria has changed the academic and clinical experience levels of perfusionists in Canada. Strategies designed to better prepare perfusionists for their clinical assignments outside the OR are merited.
Effect of External Ankle Support on Ankle and Knee Biomechanics During the Cutting Maneuver in Basketball Players
Authors: Klem Nardia-Rose , Wild Catherine Y. , Williams Sian A. , Ng Leo 
Published: November 2016

Background: Despite the high prevalence of lower extremity injuries in female basketball players as well as a high proportion of athletes who wear ankle braces, there is a paucity of research pertaining to the effects of ankle bracing on ankle and knee biomechanics during basketball-specific tasks. Purpose: To compare the effects of a lace-up brace (ASO), a hinged brace (Active T2), and no ankle bracing (control) on ankle and knee joint kinematics and joint reaction forces in female basketball athletes during a cutting maneuver. Study Design: Controlled laboratory study. Methods: Twenty healthy, semi-elite female basketball players performed a cutting task under both ankle brace conditions (lace-up ankle brace and hinged ankle brace) and a no-brace condition. The 3-dimensional kinematics of the ankle and knee during the cutting maneuver were measured with an 18-camera motion analysis system (250 Hz), and ground-reaction force data were collected by use of a multichannel force plate (2000 Hz) to quantify ankle and knee joint reaction forces. Conditions were randomized using a block randomization method. Results: Compared with the control condition, the hinged ankle brace significantly restricted peak ankle inversion (mean difference, 1.7°; P = .023). No significant difference was found between the lace-up brace and the control condition ( P = .865). Compared with the lace-up brace, the hinged brace significantly reduced ankle and knee joint compressive forces at the time of peak ankle dorsiflexion (mean difference, 1.5 N/kg [ P = .018] and 1.4 N/kg [ P = .013], respectively). Additionally, the hinged ankle brace significantly reduced knee anterior shear forces compared with the lace-up brace both during the deceleration phase and at peak ankle dorsiflexion (mean difference, 0.8 N/kg [ P = .018] and 0.9 N/kg [ P = .011], respectively). Conclusion: The hinged ankle brace significantly reduced ankle inversion compared with the no-brace condition and reduced ankle and knee joint forces compared with the lace-up brace in a female basketball population during a cutting task. Compared with the lace-up brace, the hinged brace may be a better choice of prophylactic ankle support for female basketball players from a biomechanical perspective. However, both braces increased knee internal rotation and knee abduction angles, which may be problematic for a population that already has a high prevalence of knee injuries.
Tetrabenazine in treatment of hyperkinetic movement disorders: an observational study
Authors: Miguel Rita , Mendonça Marcelo D. , Barbosa Raquel , Ladeira Filipa , Lampreia Tânia , Vale José , Bugalho Paulo 
Published: November 2016

Background: Tetrabenazine (TBZ) is commonly used in hyperkinetic movement disorders. In this retrospective study, we aimed to assess the TBZ effectiveness and adverse events (AEs) in Huntington disease (HD), vascular chorea, tics, dystonia, tardive oromandibular (OM) dyskinesia and other tardive syndromes (TS). Methods: Qualitative analysis of clinical response was used to estimate TBZ effectiveness. TBZ-associated AE frequency and subsequent discontinuation rate were used to estimate tolerability; the tolerability profile was measured through the TBZ minimal dose and exposure time required to elicit AEs. Results: Of 108 included patients, 87% had a clinically meaningful improvement sustained over a period of 40 months. TBZ-responder rate ranged from 100% in HD to 62.5% and 77.1% in tic disorders and OM dyskinesia, respectively ( p < 0.001). TBZ-associated AE frequency ranged from 40.9% in other TS and 41.7% in vascular chorea and HD, to 60% in OM dyskinesia ( p < 0.001). The most common AEs were Parkinsonism (51.8%) and psychiatric disorders (25%). The ‘other AEs’ category (mainly somnolence) presented the shortest minimal exposure time (3 months). AE-eliciting dose differed from 18.8 mg and 25 mg in tics and tardive disorders, to 75 mg in HD ( p = 0.003). Patients with AEs were tendentiously older at TBZ initiation ( p = 0.022). Conclusions: TBZ proved an effective and relatively well tolerated treatment in hyperkinetic disorders, with excellent results in HD. AEs were more common in OM dyskinesia, which may be related to higher age at TBZ initiation. TBZ-associated somnolence and Parkinsonism were more frequent during the titration and maintenance periods, respectively.
Braided tape is equivalent to modified Mason-Allen multi-strand #2 suture in subscapularis muscle repair: results of a biomechanical study
Authors: Léger-St-Jean Benjamin , Ménard Jérémie , Hinse Stéphanie , Balg Frédéric , Rouleau Dominique M 
Published: November 2016

Background To help determine the optimal fixation method for subscapularis tendon repair in arthroplasty, the present study compares single-passage transosseous tape (BT) and modified Mason-Allen #2 suture (MA). Methods Eighteen human cadaveric shoulders were randomized to two repair constructs after arthroplasty preparation. Both techniques included two transosseous passages through the bicipital groove and then through the tendon at the level of the anatomical neck. Construct was tested using a traction machine, measuring cyclic loading and ultimate load to failure. Results The mean age of our specimens was 71 years. No significant difference was observed between the repair techniques in both mean ultimate load and cyclic loading. The mean (SD) ultimate load (UL) for BT was 293 (84) N and 342 (117) N for MA, which was not statistically significant ( p = 0.374). The majority of repairs failed in the tendon. Bone cut-out was observed with the MA but not for the BT repair. No correlation was found between bone density and UL for BT ( r = −0.09) but there was strong correlation for MA ( r = 0.63). Conclusions The MA repair appears to be more dependant on bone mineral density for ultimate load, indicating that braided-tape might be better suited for osteoporotic patients to avoid bone cut-out.
Accurate Carbohydrate Counting Is an Important Determinant of Postprandial Glycemia in Children and Adolescents With Type 1 Diabetes on Insulin Pump Therapy
Authors: Deeb Asma , Al Hajeri Ahlam , Alhmoudi Iman , Nagelkerke Nico 
Published: November 2016

Background: Carbohydrate (CHO) counting is a key nutritional intervention utilized in the management of diabetes to optimize postprandial glycemia. The aim of the study was to examine the impact of accuracy of CHO counting on the postprandial glucose in children and adolescents with type 1 diabetes on insulin pump therapy. Methods: Children/adolescents with type 1 diabetes who were on insulin pump therapy for a minimum of 6 months are enrolled in the study. Patients were instructed to record details of meals consumed, estimated CHO count per meal, and 2-hour postprandial glucose readings over 3-5 days. Meals’ CHO contents were recounted by an experienced clinical dietician, and those within 20% of the dietician’s counting were considered accurate. Results: A total of 30 patients (21 females) were enrolled. Age range (median) was 8-18 (SD 13) years. Data of 247 meals were analyzed. A total of 165 (67%) meals’ CHO contents were accurately counted. Of those, 90 meals (55%) had in-target postprandial glucose ( P < .000). There was an inverse relationship between inaccurate CHO estimates and postprandial glucose. Of the 63 underestimated meals, 55 had above-target glucose, while 12 of the 19 overestimated meals were followed by low glucose. There was no association between accuracy and meal size (Spearman’s rho = .019). Conclusion: Accuracy of CHO counting is an important determining factor of postprandial glycemia. However, other factors should be considered when advising on prandial insulin calculation. Underestimation and overestimation of CHO result in postprandial hyperglycemia and hypoglycemia, respectively. Accuracy does not correlate with meal size.
Predictors of Time to Union After Operative Fixation of Closed Ankle Fractures
Authors: Matson Andrew P. , Hamid Kamran S. , Adams Samuel B. 
Published: November 2016

Background. Ankle fractures are common and represent a significant burden to society. We aim to report the rate of union as determined by clinical and radiographic data, and to identify factors that predict time to union. Methods. A cohort of 112 consecutive patients with isolated, closed, operative malleolar ankle fractures treated with open reduction and internal fixation was retrospectively reviewed for time to clinical union. Clinical union was defined based on radiographic and clinical parameters, and delayed union was defined by time to union >12 weeks. Injury characteristics, patient factors and treatment variables were recorded, and statistical techniques employed included the Chi-square test, the Student’s T-test, and multivariate linear regression modeling. Results. Forty-two (37.5%) of patients who achieved union did so in less than 12 weeks, and 69 (61.6%) of these patients demonstrated delayed union at a mean of 16.7 weeks (range, 12.1-26.7 weeks), and the remaining patient required revision surgery. Factors associated with higher rates of delayed union or increased time to union included tobacco use, bimalleolar fixation, and high energy mechanism (all p<0.05). In regression analysis, statistically significant negative predictors of time to union were BMI, dislocation of the tibiotalar joint, external fixation for initial stabilization and delay of definitive management (all p<0.05). Conclusion. Patient characteristics, injury factors and treatment variables are predictive of time to union following open reduction and internal fixation of closed ankle fractures. These findings should assist with patient counseling, and help guide the provider when considering adjunctive therapies that promote bone healing. Levels of Evidence: Prognostic, Level IV: Case series
Biomechanical Analysis of Weighted-Ball Exercises for Baseball Pitchers
Authors: Fleisig Glenn S. , Diffendaffer Alek Z. , Aune Kyle T. , Ivey Brett , Laughlin Walter A. 
Published: November 2016

Background: Weighted-ball throwing programs are commonly used in training baseball pitchers to increase ball velocity. The purpose of this study was to compare kinematics and kinetics among weighted-ball exercises with values from standard pitching (ie, pitching standard 5-oz baseballs from a mound). Hypothesis: Ball and arm velocities would be greater with lighter balls and joint kinetics would be greater with heavier balls. Study Design: Controlled laboratory study. Methods: Twenty-five high school and collegiate baseball pitchers experienced with weighted-ball throwing were tested with an automated motion capture system. Each participant performed 3 trials of 10 different exercises: pitching 4-, 5-, 6-, and 7-oz baseballs from a mound; flat-ground crow hop throws with 4-, 5-, 6-, and 7-oz baseballs; and flat-ground hold exercises with 14- and 32-oz balls. Twenty-six biomechanical parameters were computed for each trial. Data among the 10 exercises were compared with repeated measures analysis of variance and post hoc paired t tests against the standard pitching data. Results: Ball velocity increased as ball mass decreased. There were no differences in arm and trunk velocities between throwing a standard baseball and an underweight baseball (4 oz), while arm and trunk velocities steadily decreased as ball weight increased from 5 to 32 oz. Compared with values pitching from a mound, velocities of the pelvis, shoulder, and ball were increased for flat-ground throws. In general, as ball mass increased arm torques and forces decreased; the exception was elbow flexion torque, which was significantly greater for the flat-ground holds. There were significant differences in body positions when pitching on the mound, flat-ground throws, and holds. Conclusions: While ball velocity was greatest throwing underweight baseballs, results from the study did not support the rest of the hypothesis. Kinematics and kinetics were similar between underweight and standard baseballs, while overweight balls correlated with decreased arm forces, torques, and velocities. Increased ball velocity and joint velocities were produced with crow hop throws, likely because of running forward while throwing. Clinical Relevance: As pitching slightly underweight and overweight baseballs produces variations in kinematics without increased arm kinetics, these exercises seem reasonable for training pitchers. As flat-ground throwing produces increased shoulder internal rotation velocity and elbow varus torque, these exercises may be beneficial but may also be stressful and risky. Flat-ground holds with heavy balls should not be viewed as enhancing pitching biomechanics, but rather as hybrid exercises between throwing and resistance training.
Endoscopic ultrasound‐guided fine needle aspiration of pancreatic lesions with 22 versus 25 Gauge needles: A meta‐analysis
Authors: Facciorusso Antonio , Stasi Elisa , Di Maso Marianna , Serviddio Gaetano , Ali Hussein Mohammed Salah , Muscatiello Nicola 
Published: November 2016

BackgroundRobust data in favour of a clear superiority of 22 versus 25 Gauge needles for endoscopic ultrasound‐guided fine needle aspiration are still lacking.ObjectiveWe aimed to compare the diagnostic sensitivity, specificity and safety of these two needles for endoscopic ultrasound‐guided fine needle aspiration of solid pancreatic lesions.MethodsA computerized bibliographic search was restricted to randomized controlled trials only. Pooled effects were calculated using a random‐effects model and expressed in terms of risk ratio and 95% confidence interval.ResultsWe analysed seven trials with 689 patients and 732 lesions (295 sampled with 22 Gauge needle, 309 with 25 Gauge needle, and 128 with both needles). A non‐significant superiority of 25 Gauge in terms of pooled sensitivity (risk ratio: 0.93, 0.91–0.95 versus 0.89, 0.85–0.94 of 22 Gauge needle; p  = 0.13) and no difference in terms of specificity (1.00, 0.98–1.00 in both groups; p  = 0.85) were observed. Sample adequacy was similar between the two devices (risk ratio: 1.03, 0.99–1.06; p  = 0.15). Very few adverse events were observed and did not impact on patient outcomes.ConclusionOur meta‐analysis reveals non‐superiority of 25 Gauge over 22 Gauge; hence no definitive recommendations over the use of one particular device can be made.
Antibiotics impair murine hematopoiesis by depleting the intestinal microbiota
Authors: Josefsdottir Kamilla S. , Baldridge Megan T. , Kadmon Claudine S. , King Katherine Y. 
Published: November 2016

Key Points
Antibiotics cause multilineage alterations in murine hematopoiesis, with marked suppression of multipotent progenitors. Suppression of bone marrow populations results from depletion of intestinal microbiota.
B-cell receptor–driven MALT1 activity regulates MYC signaling in mantle cell lymphoma
Authors: Dai Beiying , Grau Michael , Juilland Mélanie , Klener Pavel , Höring Elisabeth , Molinsky Jan , Schimmack Gisela , Aukema Sietse M. , Hoster Eva , Vogt Niklas , Staiger Annette M. , Erdmann Tabea , Xu Wendan , Erdmann Kristian , Dzyuba Nicole , Madle Hannelore , Berdel Wolfgang E. , Trneny Marek , Dreyling Martin , Jöhrens Korinna , Lenz Peter , Rosenwald Andreas , Siebert Reiner , Tzankov Alexandar , Klapper Wolfram , Anagnostopoulos Ioannis , Krappmann Daniel , Ott German , Thome Margot , Lenz Georg 
Published: November 2016

Key PointsMALT1 protease activity stabilizes MYC. The MALT1-MYC network might represent a therapeutic target for MCL patients.