bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abstract No.: ABS2571: Comparison of postoperative analgesia and opioid requirement with thoracic epidural vs. continuous rectus sheath infusion in midline incision laparotomies under general anaesthesia. A prospective randomised controlled study.
Authors: Mounika Achanta 
Published: September 2024

Background & Aims:
To assess and compare the effect of bilateral continuous rectus sheath infusion (CRSB) for postoperative analgesia with continuous thoracic epidural infusion (TEA) in patients undergoing midline incision laparotomies

Methods:
A prospective, randomised study involving 60 patients with American Society of Anesthesiologists physical status I to III, planned for elective laparotomy were enrolled for the study. Patients were randomly allocated into two groups: TEA group: an epidural was sited before induction of general anaesthesia (GA); CRSB group: bilateral ultrasound-guided RSB catheters were placed at the end of the surgical procedure, before extubation. Both groups received continuous 0.2% ropivacaine infusion. They were followed for two post-operative days (POD). Opioid requirement and post-operative pain at rest, coughing and moving were noted. Statistical analysis was done using SPSS 21.0

Results:
Opioid consumption in both groups was comparable, for the first two post-operative days with no statistically significant difference. Pain scores were comparable among the groups at all times except POD 0 (4 h and 12 h postop) and POD 1 (8 AM and 12PM), where lower pain scores were observed in CRSB Group.

Conclusion:
As a part of the multimodal analgesia technique, CRSB offers a reliable, safe, and effective alternative to TEA
Abstract No.: ABS2686 : Evaluation of efficacy of midazolam and propofol on postoperative nausea and Vomiting in day care surgeries - A prospective clinical study
Authors: C Nivetha 
Published: September 2024

Background & Aims:
In several studies, midazolam and propofol have been demonstrated to have some benefits with regard to postoperative nausea and vomiting(PONV). The aim of the present study was to compare the efficacy of sub-hypnotic doses of midazolam and propofol to reduce the incidence of PONV.

Methods:
Eighty patients of ASA I&II were taken up for elective ambulatory surgeries under general anaesthesia. Study patients were randomly allocated into 2 groups: Group M (n=40) received Injection Midazolam 1mg Intravenously and Group P (n=40) received Injection Propofol 20 mg intravenously 15 mins before extubation. Any additional antiemetic given to treat PONV was noted. Nausea and vomiting score was used to assess these symptoms, immediately, at 30 mins, 2hrs, 4hrs, and 6 hrs. Intraoperative and postoperative haemodynamic status and sedation were recorded and data collected was analysed statistically.

Results:
After extubation, the incidence of nausea was 5% in group P, 10% in group M, and retching was 2.5% in bothgroups(P=0.835). After 30 minutes, nausea was 15% in group P, 12.5% in group M, retching was 2.5% in both the groups(P=0.948). At 2 hours, nausea occurred in 2.5% in group P and 5% of patients in group M(P=0.556). At 4th/6th hours, no PONV occured. There was no significant difference in haemodynamic or sedation scores.

Conclusion:
From the results of the present study, it can be concluded that both that IV midazolam 1 mg and IV propofol 20 mg given 15 minutes beforeextubation are equally efficacious in preventing post-operative nausea and vomiting in patients undergoing day care surgeries.
Abstract No. : ABS2860 : Comparative evaluation of conventional versus pulsed versus combined radiofrequency ablation for trigeminal neuralgia
Authors: Kumar Amit 
Published: September 2024

Background and Aims:
Trigeminal neuralgia is a manifestation of orofacial neuropathic pain restricted to one or more divisions of the trigeminal nerve. This prospective study was conducted to compare the safety and efficacy of conventional versus pulsed versus combined radiofrequency ablation for treatment.

Methods:
The patients were divided in three groups of 20 each. In group I (n=20), patients were administered fluoroscope guided conventional radiofrequency ablation at 75°C and thermal lesion was applied for 270 seconds. In group II (n=20), patients were administered fluoroscope guided pulsed radiofrequency ablation for 10 minutes at 45 V, with a pulse width of 10 ms and a pulse frequency of 4 Hz at 42°C. In group III (n=20), patients were administered fluoroscopic guided conventional radiofrequency ablation followed by pulsed radiofrequency ablation. Patients were followed up for a period of three months.

Results:
Pain scores (visual analogue scale) were found comparable between the three groups at all the time points (p>0.05). Vital parameters like heart rate, systolic and diastolic blood pressures were also comparable amongst the three groups at different time points and showed no statistical significance (p>0.05). None of the patients reported any serious complications.

Conclusion:
All the three procedures, conventional radiofrequency, pulsed radiofrequency and combined conventional and pulsed radiofrequency are safe and effective techniques for management of patients with trigeminal neuralgia, with comparable efficacy. All the techniques provide good pain relief and improvement in disability to the patients.
Abstract No. : ABS2908: Comparison of recovery characteristics of 2-chlorprocaine 40 mg and low dose Bupivacaine 10 mg under spinal anaesthesiafor short duration surgeries
Authors: Chaudhari Bhoomika 
Published: September 2024

Background &Aims:
Comparison of recovery characteristics by comparing two drugs in short duration surgeries by comparing sensory and motor regression, time to achieve successful micturition and assisted ambulation were the objectives of the study.

Methods:
This observational study was conducted in 30 individuals in group A for drug 2- chlorprocaine 40 mg, 30 patients in group B for Bupivacaine 10 mg with age group of 18 to 60 years and with AmericanSocietyofAnesthesiologistsclass I, II, III posted for short duration surgeries. After taking informed written consent, the drug was given intrathecally under strict aseptic precautions in lateral decubitus position. From achieving maximum sensory level, time to sensory regression upto S2 level ,modifiedBromage scale 0, successful micturition time and assisted ambulation time were recorded and compared between both the groups.

Results:
The time differences between both group A and B; sensory regression was 141.21Â± 23.05 min and 91.53 Â±29.30 min with p value 0.00001 ;for motor regression 138.85Â±24.6 min and 85.38Â±27.91 min with p value <0.00001; For micturition178.21 Â± 27.05 min and 115 Â± 32.81 min with p value 0.00002 and for assisted ambulation 162.21Â±27.57 min and 95.53 Â± 37.281 min with p value of 0.000017. There was a significant difference in regression between both the groups.

Conclusion:
Bupivacaine has slower regression of motor and sensory effect while time to achieve micturition and assisted ambulation is lesser with 2-chlorprocaine as compared to bupivacaine.
Abstract No.: ABS3031: Effect of nebulised dexmedetomidine on parental separation in paediatric patients
Authors: JutooruShreehari  
Published: September 2024

Background & Aims:
Fear of parental separation causes preoperative anxiety in 50-70% of paediatric patients leading to high incidence of postoperative pain, emergence. Inhalation of nebuliser drug provides alternative to preoperative sedation in children and needle puncture from intravenous/intramuscular (iv/im) can be avoided.

Methods:
In this prospective randomiseddouble blind study 92 patients aged between 1-10 years were taken. Patients were divided into two groups as Group D and group C. Patients were kept fasting according to American Society of Anesthesiologists (ASA) guidelines. Group D received nebulised dexmedetomidine 2 µg/kg) and Group C received nebulised NS preoperatively. Parental separation anxiety scale (PSAS) at 20 min after the end of nebulisation was compared between the two groups while shifting to operating room.
Patients were monitored intraoperatively and postoperatively for one hour. Statistical analysis was done using chi-square test. A p value of <0.05 was considered significant.

Results:
Parameters were compared between C and D group..Parental separation was satisfactory in group D (p = 0.020)compared to group C.

Conclusion:
Nebulised dexmedetomidine can be used as a premedicant in paediatric patients preoperatively, as it provides better parental separation and reduces anxiety.
Abstract No.: ABS3159: Utility of prognostic scores in prediction of mortality after emergency surgery in COVID-19 patients – A prospective observational cohort study
Authors: Karna Sunaina Tejpal 
Published: September 2024

Background and Aims:
Pre-operative prognostic scoring in emergency surgeries is important for informed consent and optimum resource allocation. The accuracy of pre-operative prognostic scores in patients with coronavirus disease (COVID-19) has not been studied. This study aimed to evaluate prognostic scoring tools in COVID-19 patients.

Methods:
A prospective, observational cohort study was conducted in adults with confirmed COVID-19 infection within 7 weeks before or 1 week after emergency surgery. (1) Demographic data, prognostic risk scores [American Association of Anaesthesiologists Physical Classification (ASA), sequential organ failure assessment (SOFA), quick SOFA (qSOFA), Physiologic and Operative Severity Score for enUmeration of Mortality and Morbidity (POSSUM), and Portsmouth POSSUM (P-POSSUM) scores], and surgical and anaesthetic factors were noted along with morbidity and 30-day mortality. The correlation of prognostic scores and mortality was evaluated using univariate Cox proportional hazards regression, receiver operating characteristic curves (ROCs), Youden’s index, and the Hosmer–Lemeshow goodness-of-fit model.

Results:
Sixty-seven COVID-19 patients underwent emergency surgery during the study period. The overall mortality was 19%, with the highest in gastro-intestinal/general surgery and sinus surgery. Positive qSOFA and ASA 3E/4E were associated with 9.03 and 12.7 times higher mortality risk, respectively. Each unit increase of SOFA-, POSSUM-, and P-POSSUM-predicted mortality scores led to 50%, 7%, and 6% higher mortality. SOFA, POSSUM, and P-POSSUM area under the curve–ROC curves showed good discrimination between survivors and non-survivors (AUC 0.8829, 0.85, and 0.86, respectively).

Conclusion:
The overall mortality was comparable to the published literature. (2) SOFA, POSSUM, and P-POSSUM models are good prognostictools for predicting the post-operative 30-day mortality in COVID-19 patients. qSOFA, a simple, clinical, objective tool, also has an aprognostic value.
Abstract No.: ABS3164 : Awake fiberoptic intubation in paediatric patients with temporomandibular joint ankylosis
Authors: Gandhi Atul 
Published: September 2024

Background and Aims:
Endotracheal Intubation in temporomandibular joint (TMJ) ankylosis is considered as difficult airway manaegment. Fibreoptic intubation is the gold standard for TMJ ankylosis.

Methods:
In the present study 30 patients aged 5 -14 yrs were enroled for awake fiberoptic intubation [Table 1]. The procdure of awake fiberoptic intubation was explained to them. Patients were preoxygentaion for 5 min using nasal airway. All patient xyolcaine jelly was inserted in more patent nostril and nostril and 1% inj xylocaine was injected trans-tracheal. Following this trachea was intubated using fiber optic intubation. The correct placement of tracheal tube was confirmed with chest auscultation and and endtidal carbondioxide monitoring.

JOURNAL/ijana/04.03/01762628-202203001-00073/inline-graphic1/v/2022-09-30T091728Z/r/image-tiff

Results:
Out of 30 patients,three patients could not be intubated and tracheostomy was done in one patient and in two patients surgery was postponed. In these 2 patients surgery which was done after two weeks using fiberoptic intubation successfully using spontaneous ventilation with oxygen in sevoflurane.

Conclusion:
The use of awake fiberoptic intubation after explaining to patients and parents resulted in successful outcome in patients of TM ankylosis.
Abstract No. : ABS3199: Comparison of self-selected music and prefixed music on reduction of perioperative Anxiety in adult Patients undergoing laparoscopic surgeries under general Anaesthesia
Authors: V Meghana K 
Published: September 2024

Background &Aims:
Preoperativeanxiety in patientsis associated with psychological effects.The current study aimed to compare the effects of self selected(SS) musicand prefixed (PF) musicin reducing preoperative anxiety.

Methods:
In this study, 90 patients posted for laparoscopic cholecystectomy were randomly divided into three groups equally. Patients in group SS and group PF listened toSSand PFfor 20 minutes in preoperative roomrespectively. Music continued until reversal of anaesthesia. Vitals of patients, VASscore for pain and post operative nausea and vomiting (PONV)score were noted at 1st and 2nd hour after surgery.

Results:
There was a statistically significant difference in anxiety score between SS and PF (p<0.05), between SS and Control(C)(p<0.05) and between PF and C (p<0.05). After music intervention of 20 minutes , heart rate, SBP at T2 was significantly reduced in SS and PF. At T5, thePONVscore was lower in SS and PF than C. There was significant difference in PONV score between SS and C (p<0.0001) and between PF and C (p<0.0003) There was significant difference inVASscore between SS and PF (p<0.05) , between SS and C (p<0.0001) and between PF and C (p<0.0001)

Conclusion:
SSmusic was more effectiveandenabled to maintain stable haemodynamic parameters throughout the surgery in reducing anxiety than PFmusic. PONV scores were comparable between SS and PFmusicgroups. SS music was more efficient in providing pain relief than PF music.
Abstract No.: ABS3215: Superior trunk block: An unorthodox alternative to interscalene block for proximal humerus surgeries in patients with significant pulmonary disease
Authors: L Darshan R 
Published: September 2024

Background and Aims:
Proximal shoulder surgery in patients with compromised pulmonary function stipulated the utilisation of superior trunk block, which spares phrenic nerve,as an alternative to interscalene block. This modificationallows patients to execute normal respiration perioperatively.This case series reports the efficacy of the block.

Methods:
Eight patients aged between 40 years to 80 years with significant restrictive, obstructive pulmonary disease and post-COVID 19 sequelae, posted for proximal humerus surgeries received the block. The block was performed under ultrasound guidance using 23 gauge Quincke spinal needle with 1:1 local anaesthetic mixture of 2% lignocaine+adrenaline and 0.5% bupivacaine with total volume injected being 15ml. The outcomes measured were loss of shoulder abduction, numbness of shoulder and pain relief, numbness of arm ,sonographic assessment of diaphragm movement, oxygen saturation perioperatively and closed-circuit measurement of the tidal volume generated.

Results:
Seven patients with superior trunk block achieved complete surgical anaesthesia of proximal shoulder. There was solitary use of dexmedetomidine for a patient with severe anxiety. Two patients required oxygen supplementation throughout the intraoperative period extending to post-operative period as well. Sonographic assessment intraoperatively and post-operatively disclosed adequate diaphragmatic excursion in all patients (table 1). Post-operative pain scores revealed satisfactory pain relief.

Conclusion:
Effective surgical anaesthesia and analgesia is delivered considerably with superior trunk block for surgeries of proximal humerus in patients with compromised pulmonary function by sparing phrenic nerve and is an appropriate substitute for interscalene block.

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Abstract No.: ABS3227: To study the efficacy of ultrasound guided quadratus lumborum block for post Operative analgesia after lower segment caesarean section: a randomised prospective controlled study
Authors: Shukla Pragya 
Published: September 2024

Background & Aims:
Various previous studies have shown the role of quadratus lumborum block (QLB)in post operative pain management after lower abdominal surgeries; so we assessed its role in post operative analgesia (measured with NRS score) after LSCS and compared it with wound infiltration.

Methods:
Sixty-seven patients who were American Society of Anesthesiologists physical statusII, with normal singleton pregnancies with a gestation of at least 37 weeks, and scheduled for elective caesarean section under spinal anaesthesia, were enroled into the study. They were randomly assigned to receive a QLB (n =30) with 0.25% levobupivacaine 15 ml on each side (total 30 ml) (Group 1) or a wound infiltration group (n =37) with same volume of drug.

Results:
USG QLB proved to be significantly more efficacious in the management of postoperative analgesia after lower segment caesarean section as compared to wound infiltration. It leads to less opioid consumption with no side effects related to opioid and having advantages of less rescue analgesia requirement along with early ambulation, and early lactation better satisfaction and better care of the new born.

Conclusion:
The study showed that ultrasound guided QLB proved to be significantly more efficacious in the management of postoperative analgesia after lower segment caesarean section as compared to wound infiltration. Overall pregnant females who were given QLB were more satisfied in terms of quality of pain relief, with early ambulation, and early lactation with better care of the new born.

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Abstract No.: ABS3480 : Dynamometer based hand grip strength as a clinical tool for objective assessment of post-operative residual muscle weakness
Authors: Pratyusha A Chaitanya 
Published: September 2024

Background and Aims:
Residual neuromuscular block is a known postoperative complication. Even after train of four (TOF) ratio of >0.9, there is a possibility of neuromuscular blockade causing respiratory dysfunction. Primary objective was assessment of postoperative residual muscle weakness with dynamometer. Secondary objective was time of recovery to baseline strength.

Methods:
This was a single centre, prospective, observational study. We enroled 50 patients undergoing surgery under general anesthesia. The patients of Americal Society of Anesthesiologists physical status I-II, aged 18-60 years and undergoing surgery under general anaesthesia were included. The patients with surgery including fracture, deformity involving dominant upper limb and pre-existing neuromuscular diseases were excluded from the study. Baseline handgrip strength with dynamometer and peak expiratory flow rate (PEFR) were observed before induction of anaesthesia. Trachea was extubated with TOF ratio >0.9. Values monitored at 15 minutes after extubation,at regular intervals of 15 minutes until 1 hour, 30 minutes until 4 hours and hourly until 6 hours.

Results:
Muscle strength remained 50 to 60% of baseline at 15 minutes, 75% at 45 minutes and reached 100% of baseline at 210 minutes after endotracheal extubation. PEFR remained 50 - 60 % of baseline at 15minutes, 75% of baseline at 60 minutes and reached 100% of baseline at 180 minutes after endotracheal extubation (Table 1).

Conclusion:
A significant reduction in the postoperative muscle strength was detected using objective force dynamometer to measure handgrip strength even when TOF ratio had returned to 1 with no clinical signs of muscle weakness.

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Abstract No.: ABS3564: Comparison of bilateral ilioinguinal-iliohypogastric nerve block versus transversus abdominis plane block for postoperative pain relief in parturients undergoing caesarean section under spinal anaesthesia.
Authors: Dhuliya Sandeepkumar 
Published: September 2024

Background & Aims:
The postoperative pain after caesarean section is believed to be of mild to moderate intensity lasting for up to 72hours. This study aims to compare transversus abdominis plane (TAP) block versus ilioinguinal / iliohypogastric (II/IH) block for post-caesarean delivery analgesia.

Methods:
The study was conducted in 56 pregnant women aged between 18-35years scheduled for caesarean section under spinal anaesthesia. They were randomised to either TAPblock( Inj.bupivacaine plain 0.25%20cc bilateral) or II/IH block(Inj.bupivacaine plain 0.25%20cc bilateral) given for postoperative pain management at the end of surgery.Total tramadol consumption, time to first analgesic request were assessed during the first 48 hours postoperatively.

Results:
The cumulative median tramadol consumption over 48 h was 16.96+/-32.66mg for TAP group and 56.25+/-57.98mg for II/IH. The median tramadol consumption at 24h was also lower in the TAP group compared to II-IH. There was no statistically significant difference between the groups regarding time to first analgesia request (p > 0.05).

Conclusion:
Both II-IH and TAP block had comparable analgesic efficacy during the first 24h. TAP block had longer analgesic effectiveness compared to II-IH with an effect lasting for 48h.

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Abstract No. : ABS3718: Comparison of ketamine-dexmedetomidine versus ketamine-propofol combination for sedation during short duration urological procedure: A randomised study
Authors: Prajapati Dineshbhai 
Published: September 2024

Background and Aims:
The present study aimed to compare safety and efficacy of ketamine-dexmedetomidine (KD) with ketamine- Propofol (KP) for sedation during short-duration urological procedure.

Methods:
The present study enroled and randomised 60 patients into either of the two groups. In Group KD (n=30) received inj dexmedetomidine 1.0 µ/ kg over 10 minutes intravenously followed by inj. ketamine 1 mg/kg as initial dose followed by 0.25mg/kg in titration. In Group KP (n=30) patients received inj propofol 1mg/kg with inj ketamine 1mg/kg as initial dose followed by the same combination top-up dose 0.25mg/kg in titration. Sedation score, Memorial delirium assessment Scale (MIDS), postoperative pain scores and recovery time were recorded. For Independent-samples, t-test was used and for proportion of significance, Chi-square test was used.

Results:
Post anaesthesia recovery scores (PARS) were 9.03±0.45 in Group KP and 9.06Â±0.36 in Group KD, p value= 0.79. No significant differences were observed in the level of sedation, PARS and postoperative pain in both the groups. In Group KD, patients were haemodynamically stable as compared to Group KP. There were no episode of apnea in Group KD as compared 6 episodes in Group KP, (p=0.005). No significant adverse event were reported in both the groups.

Conclusion:
No differences were observed in sedation score and recovery period in both the groups. Patients in Group KD experienced reduced respiratory depression as compared to Group K. Sedation with Ketamine-dexmedetomidine can be considered as a useful alternative to ketamine-propofol in short urological procedures.