bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENENTUAN KOMBINASI MEDIUM TERBAIK GALAKTOSA DAN SUMBER NITROGEN PADA PROSES PRODUKSI ETANOL
Authors: Sunaryanto Rofiq , Handayani Berti Hariasih 
Published: December 2017

Ethanol is an important product for biotechnology-based industries. Ethanol can be produced from various raw materials and some types of microbes. Determination of the best combination of galactose with nitrogen sources on ethanol production using Saccharomyces cerevisiae has been done. Combination of galactose at the concentration of 3 g/L and 20 g/L with nitrogen sources (casein, peptone, and urea, each at the concentration of 10g/L) was used to obtain the best composition of fermentation medium. Fermentation was carried out for 60 hours at 30°C, 250 rpm, and working volume of 50 mL in a 250 mL erlenmeyer. The results showed that the galactose concentration of 20 g/L was able to improve the productivity of ethanol and the growth of S. cerevisiae cells. The combination of 20g/L galactose and 10 g/L casein produced the highest ethanol concentration (6% v/v), whereas 20 g/L galactose-10 g/L peptone and 20 g/L galactose-10 g/L urea combinations produced 2.5% and 0.58% (v/v) ethanol, respectively. The use of 3 g/L galactose mixed with several nitrogen sources produced ethanol below 0.7% (v/v). Keywords: Ethanol, galactose, peptone, casein, Saccharomyces cerevisiaeABSTRAKEtanol merupakan salah satu produk penting bagi industri yang berbasis bioteknologi. Etanol dapat dihasilkan dari berbagai macam bahan baku dan beberapa jenis mikroba. Penentuan kombinasi terbaik antara galaktosa dengan sumber nitrogen pada produksi etanol menggunakan Saccharomyces cerevisiae telah dilakukan. Konsentrasi galaktosa 3 g/L dan galaktosa 20 g/L yang dikombinasikan dengan sumber nitrogen dengan konsentrasi 10 g/L dalam hal ini kasein, pepton, dan urea digunakan sebagai perlakuan untuk mendapatkan kombinasi medium sumber karbon dan sumber nitrogen terbaik. Fermentasi untuk menghasilkan etanol dilakukan selama 60 jam pada suhu 30°C, agitasi 250 rpm dengan volume kerja 50 mL dalam erlenmeyer 250 mL. Hasil penelitian menunjukkan penambahan galaktosa dengan konsentrasi sampai dengan 20 g/L mampu memperbaiki produktivitas etanol dan pertumbuhan sel S. cerevisiae. Konsentrasi 20 g/L galaktosa dengan 10 g/L kasein menghasilkan produktivitas etanol paling tinggi yaitu 6%(v/v), konsentrasi galaktosa 20 g/L dengan 10 g/L pepton menghasilkan 2,5% (v/v) etanol dan konsentrasi galaktosa 20 g/L dengan 10 g/L urea menghasilkan 0,58%(v/v) etanol. Penggunaan konsentrasi galaktosa 3 g/L yang dikombinasikan dengan beberapa jenis sumber nitrogen menghasilkan etanol dibawah 0,7% (v/v).Kata kunci: Etanol, galaktosa, pepton, kasein, Saccharomyces cerevisiae
THE COMBINATION OF GROWTH HORMONES INCREASED THE IN VITRO SHOOTS MULTIPLICATION ON SAGO PALM (Metroxylon sagu Rottb.)
Authors: Tajuddin Teuku , . Karyanti , Sukarnih Tati , Haska Nadirman 
Published: December 2017

Pohon sagu (Metroxylon sagu Rottb.) mempunyai banyak keunggulan dibanding dengan tanaman-tanaman penghasil pati lainnya, khususnya karena memiliki produktivitas yang tinggi, tumbuh di area bantaran sungai dan rawa, yang merupakan lingkungan tidak sesuai bagi pertumbuhan tanaman-tanaman lain. Dalam rangka membangun suatu perkebunan sagu di area yang luas, maka sangat dibutuhkan anakan-anakan sagu yang ukurannya seragam dalam jumlah yang besar. Namun demikian, terbatasnya jumlah anakan yang seragam telah menjadi kendala bagi pengembangan perkebunan sagu. Sebagai alternatif, perbanyakan in vitro dengan induksi tunas langsung dilakukan untuk mendapatkan bibit-bibit sagu dengan genotip unggul secara masal. Anakan sagu yang diperoleh dari Propinsi Maluku digunakan sebagai sumber eksplan. Eksplan dikultur pada media MS dan B5 yang mengandung kombinasi hormon auksin dan sitokinin. Hasil penelitian menunjukkan bahwa perlakuan BAP 2.0 ppm dan NAA 2.0 ppm menghasilkan jumlah tunas terbanyak.Kata kunci: Auksin, sitokinin, in vitro, sagu, inisiasi tunas ABSTRACTSago palm (Metroxylon sagu Rottb.) has many advantages over other starch-producing crops especially for its higher yield, ability to grow along riverbanks and on swampy areas not suitable for other crops. With the purpose of establishing large-scale plantations, a large amount of uniform sago palm suckers are required. However, limited availability of uniform suckers has hindered the mass propagation and development of cultivated Sago palm. Alternatively, in vitro cultures were performed in order to obtain a large-scale of mass clonally propagation of superior genotypes of sago palm. The young suckers obtained from areas of Maluku Province were used as explants. In vitro culture was carried out through direct shooting. The explants were cultured on two kinds of media, which were MS and B5 media containing various growth hormones of auxins and cytokinins. The results showed that the treatment with BAP 2.0 ppm and NAA 2.0 ppm produced the highest number of shoots.Keywords: Auxin, cytokinin, in vitro, sago palm, shoot initiation
ANALISIS KORELASI KERAPATAN TITIK API DENGAN CURAH HUJAN DI PULAU SUMATERA DAN KALIMANTAN
Authors: Prayoga M. Bayu Rizky , Yananto Ardila , Kusumo Della Ananto 
Published: December 2017

IntisariKebakaran hutan dan lahan merupakan bencana yang rutin terjadi di Indonesia. Pulau Sumatera dan Kalimantan menjadi wilayah yang paling sering dilanda kebakaran hutan dan lahan. Munculnya titik api di wilayah Sumatera dan Kalimantan mempunyai pola tersendiri. Penelitian ini bertujuan untuk mengetahui secara spasial-temporal konsentrasi titik api di wilayah Sumatera dan Kalimantan serta korelasinya dengan curah hujan. Berdasarkan hasil pengolahan data titik api yang bersumber dari hasil perekaman citra MODIS (Satelit Terra & Aqua) tahun 2006-2015, didapatkan bahwa kerapatan titik api di Pulau Sumatera dan Kalimantan akan mencapai puncaknya pada bulan September. Wilayah yang memiliki konsentrasi titik api paling tinggi adalah Provinsi Riau dan Sumatera Selatan di Pulau Sumatera serta Provinsi Kalimantan Tengah dan Kalimantan Barat di Pulau Kalimantan. Hasil pengolahan data curah hujan bulanan juga menunjukkan bahwa pada bulan September curah hujan di Pulau Sumatera dan Kalimantan mencapai nilai terendah dalam satu tahun, yaitu 25-150 mm/bulan. Selain itu, korelasi antara jumlah titik api dan curah hujan menunjukkan nilai korelasi yang cukup (R = 0,307) dengan pola hubungan yang negatif. Hasil pengolahan terhadap data historis titik api ini bisa menjadi acuan dalam kesiapan penanggulangan bencana kebakaran hutan dan lahan yang sering terjadi di Pulau Sumatera dan Kalimantan. AbstractForest fire is one of disasters that occur regularly in Indonesia. Sumatera and Borneo are regions with the most frequently hit by forest fires disaster through years. The emergence of hotspots in Sumatera and Borneo have it own patterns. This study aimed to figure hotspot density in Sumatera and Borneo spatial-temporally and their correlation with rainfall. Based on the results of data processing hotspots sourced from recording of MODIS satellite (Terra and Aqua) 2006 - 2015, it was found that the density of hotspots in Sumatra and Kalimantan will reach its peak in September. Riau and South Sumatera Province are the regions that has highest concentration of hotspots in Sumatera island, meanwhile Central Borneo and West Borneo Province become the regions that has highest concentration of hotspots in Borneo island. The processing of monthly rainfall data also shown that in September rainfall in Sumatra and Kalimantan reach its lowest level in a year, which is 25 - 150 mm/month. In addition, hotspot density and rainfall are correlated enough (R = 0,307). The results of the processing of historical hotspots data in this paper could become a reference for forest fires disaster management that often happens in Sumatera and Borneo.
OPTIMASI FORMULA EDIBLE FILM BERBASIS AMILOPEKTIN PATI SINGKONG DAN KARAGENAN
Authors: Purwoto Heri , Christi A G Jeni 
Published: December 2017

Penelitian ini dilakukan untuk mendapatkan formula optimum antara amilopektin pati singkong dan karagenan sebagai bahan baku edible film. Program DesignÂ Expert 7.0.0 (trial version) dengan Response Surface Methodology (RSM) CentralÂ Composite Design (CCD) digunakan untuk mengoptimasi formula edible film.Â Variabel bebas yang digunakan yaitu persentase amilopektin, karagenan danÂ gliserin. Variabel respon yang diukur dan dioptimasi yaitu laju transmisi uap air,Â kuat tarik dan modulus elastisitas. Hasil optimasi dari program Design Expert 7.0.0Â merekomendasikan 15 solusi optimasi dengan nilai desirability tertinggi sebesarÂ 0.821. Formula satu dipilih untuk divalidasi dengan faktor-faktor yaitu amilopektinÂ 3.00 %, karagenan 2.00 %, dan gliserin 2.00 %. Nilai respon prediksi untuk lajuÂ transmisi uap air sebesar 16.331 g/m2/24 jam, kuat tarik sebesar 180.657 kgf/cm2Â dan modulus elastisitas sebesar 139.262 kgf/cm2. Nilai hasil validasi untuk lajuÂ transmis uap air sebesar 16.1027 g/m2/24 jam, kuat tarik sebesar 208.42 kgf/cm2Â dan modulus elastisitas sebesar 183.05 kgf/cm2, sehingga solusi yangÂ direkomendasikan oleh program sudah cukup baik.
APLICAÇÃO DE PRECEITOS DA EDUCAÇÃO PARA SUSTENTABILIDADE: UM ESTUDO DE PROJETOS DE TRABALHOS DE CONCLUSÃO NO CURSO SUPERIOR DE TECNOLOGIA EM DESIGN DE PRODUTO DO IFSC
Authors: Neves Carla , Bugliani Raquel , Neves Rafael Burlani , Ferreira Marcelo Gomes Gitirana 
Published: December 2017

Este artigo tem como objetivo compreender a aplicação dos princípios da sustentabilidade no quadro curricular do Curso Superior de Tecnologia em Design de Produto do IF-SC e quais são as falhas e potencialidades que devem ser exploradas para obter-se uma perspectiva no sentido da educação para a sustentabilidade. Pautando-se neste cenário, analisa-se também o nível de introdução dos princípios da sustentabilidade e gestão ambiental na relação design / empresas e qual o nível de intervenção permitida ou concretizada pelos acadêmicos do referido curso diante deste relacionamento. Para tanto, adotou-se a seguinte metodologia: análise dos TCCs desenvolvidos no período de 2009 e 2010; uma pesquisa de opinião com os alunos envolvidos e a avaliação das políticas ambientais das empresas parceiras. Disto, observou-se uma lacuna na aplicação dos aspectos concernentes à teoria e à prática para à sustentabilidade.
APLICAÇÃO DE PRINCÍPIOS DE SUSTENTABILIDADE EM EMPREENDIMENTOS DE GRANDE PORTE: POSICIONAMENTO DOS ARQUITETOS
Authors: Prizibela Silvio , De Oliveira Roberto 
Published: December 2017

Visando contribuir para o desenvolvimento de metodologias projetuais para edificações mais sustentáveis este estudo teve o objetivo geral de verificar o posicionamento dos arquitetos na aplicação de princípios de melhoria da sustentabilidade em empreendimentos de grande porte. O universo da pesquisa foram os arquitetos responsáveis pelo projeto do condomínio Pedra Branca em Palhoça – SC. Os procedimentos metodológicos utilizados foram: pesquisa bibliográfica e de opinião e visita técnica. Os estudos revelam que, embora haja preocupação por parte dos arquitetos para a aplicação de estratégias de sustentabilidade no projeto, existe contrariedade de interesses dos investidores que, por vezes, consideram o lucro. Dentre as ferramentas e procedimentos que podem auxiliar na prática projetual mais sustentável, as simulações ambientais foram consideradas as mais relevantes, contudo, as leis e normas aparecem como as opções mais utilizadas pelos entrevistados. Os resultados obtidos revelam caminhos a seguir e abordagens consistentes para fomentar práticas mais sustentáveis na arquitetura.
EL PROYECTO URBANO – ARQUITECTÓNICO EN LA TRANSFORMACIÓN PARTICIPATIVA DEL ESPACIO PÚBLICO
Authors: Vallejo Paola , Mena Fredy , Benavides Andrea Jaramillo 
Published: December 2017

El diseño urbano-arquitectónico participativo busca potenciar las capacidades de la población, promover la cooperación y fortalecer los canales de comunicación entre los beneficiarios para llevar adelante procesos de diseño del espacio público, cuyos resultados se constituyan en herramienta de gestión para la comunidad. Este artículo presenta el caso de dos intervenciones en las ciudades de Saquisilí y Quito en Ecuador, lideradas por un equipo de estudiantes y docentes de las universidades Tecnológica Equinoccial y Central, en las cuales, a partir de un análisis diagnóstico se desarrollaron estrategias de transformación del espacio público involucrando a la comunidad. Los dos proyectos fueron ejecutados durante tres años y el impacto social generado fue significativo tanto para la comunidad como para los estudiantes que enfrentaron problemas sociales tangibles y llegaron a soluciones usando el mínimo de recursos materiales.
Letting In and Shutting Out: Themes in the Thought of C. S. Lewis
Authors: Patrick Meriel 
Published: December 2017

This article considers two related themes from the writings of C.S. Lewis: the desire to be granted admittance to an exclusive circle (which Lewis calls ‘The Inner Ring’ – discussed at length in his 1944 oration of that name) with its corresponding dread of being left outside, and the opposite fear of being ‘drawn in’ to something against one’s will, and finding oneself trapped inside a community or way of life to which one never intended to commit oneself. In Lewis’s fiction, these desires and fears are most obviously exemplified in the characters of Mark and Jane Studdock from the third novel in the Cosmic Trilogy, That Hideous Strength: Mark is terrified of being shut out, and Jane of being shut in. After offering some thoughts on the journey that each undertakes and the struggles that the couple find themselves engaged in during the course of the book, the article concludes with some reflections on the broader theological significance that the themes of admission and exclusion have in Lewis’s thought.
Danse, la cité. Infiltration chorégraphique d’une place publique
Authors: Massiani Léna 
Published: December 2017

Danse, la cité est une action artistique urbaine qui interroge la relation entre les habitants d’un quartier et une place publique. C’est donc en leur présence qu’elle s’élabore. Ceux-ci sont invités à observer leur environnement quotidiennement traversé, ils sont invités à l’éprouver par un geste expérimental, pour enfin l’investir grâce à une performance dansée. La recherche qui a été mise en œuvre avec les habitants est issue de l’observation sensible que tous les participants ont réalisé au préalable. Celle-ci utilise les caractéristiques du chorégraphique comme un moyen d’identifier l’effet d’un espace sur le corps. En filigrane, le projet ouvre la voie d’une démarche singulière : lire et comprendre l’espace urbain par le corps sensible.
Advanced Practice Registered Nurses on Therapeutic Hypothermia Response Teams
Authors: Wannemacher Jason , Tschannen Dana , Biery Kim , Arslanian-Engoren Cynthia 
Published: December 2017

Background:
Therapeutic hypothermia can improve neurological recovery after cardiac arrest when implemented quickly.

Objective:
To determine whether outcomes are improved among patients undergoing therapeutic hypothermia by adding advanced practice registered nurses to a therapeutic hypothermia response team.

Methods:
A pilot quality improvement project was conducted in a Midwest community teaching hospital using a retrospective chart review of all adult patients undergoing therapeutic hypothermia before and after the addition of advanced practice registered nurses to the therapeutic hypothermia response team. Outcomes evaluated included time to target core body temperature, therapeutic hypothermia protocol initiation, discharge status, and hospital length of stay.

Results:
A total of 14 adult patients (preintervention n = 8, postintervention n = 6) comprised the sample. Length of stay decreased in the postintervention group (median 2.5 vs 6 days for the preintervention group; P = .05), but other outcomes did not differ.

Conclusions:
This quality improvement project provides foundational data to evaluate advanced practice registered nurses specific metrics and to compare with future data using a larger longitudinal sample.
Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-β–Mediated Tumor Immune Evasion
Authors: Ibrahim Mohsen , Scozzi Davide , Toth Kelsey A. , Ponti Donatella , Kreisel Daniel , Menna Cecilia , De Falco Elena , D’Andrilli Antonio , Rendina Erino A. , Calogero Antonella , Krupnick Alexander S. , Gelman Andrew E. 
Published: December 2017

Abstract
TLR agonists are effective at treating superficial cancerous lesions, but their use internally for other types of tumors remains challenging because of toxicity. In this article, we report that murine and human naive CD4+ T cells that sequester Pam3Cys4 (CD4+ TPam3) become primed for Th1 differentiation. CD4+ TPam3 cells encoding the OVA-specific TCR OT2, when transferred into mice bearing established TGF-β–OVA–expressing thymomas, produce high amounts of IFN-γ and sensitize tumors to PD-1/programmed cell death ligand 1 blockade–induced rejection. In contrast, naive OT2 cells without Pam3Cys4 cargo are prone to TGF-β–dependent inducible regulatory Foxp3+ CD4+ T cell conversion and accelerate tumor growth that is largely unaffected by PD-1/programmed cell death ligand 1 blockade. Ex vivo analysis reveals that CD4+ TPam3 cells are resistant to TGF-β–mediated gene expression through Akt activation controlled by inputs from the TCR and a TLR2-MyD88–dependent PI3K signaling pathway. These data show that CD4+ TPam3 cells are capable of Th1 differentiation in the presence of TGF-β, suggesting a novel approach to adoptive cell therapy.
Cyclic GMP–AMP Synthase Is the Cytosolic Sensor of Plasmodium falciparum Genomic DNA and Activates Type I IFN in Malaria
Authors: Gallego-Marin Carolina , Schrum Jacob E. , Andrade Warrison A. , Shaffer Scott A. , Giraldo Lina F. , Lasso Alvaro M. , Kurt-Jones Evelyn A. , Fitzgerald Katherine A. , Golenbock Douglas T. 
Published: December 2017

Abstract
Innate immune receptors have a key role in the sensing of malaria and initiating immune responses. As a consequence of infection, systemic inflammation emerges and is directly related to signs and symptoms during acute disease. We have previously reported that plasmodial DNA is the primary driver of systemic inflammation in malaria, both within the phagolysosome and in the cytosol of effector cells. In this article, we demonstrate that Plasmodium falciparum genomic DNA delivered to the cytosol of human monocytes binds and activates cyclic GMP–AMP synthase (cGAS). Activated cGAS synthesizes 2′3′-cGAMP, which we subsequently can detect using liquid chromatography–tandem mass spectrometry. 2′3′-cGAMP acts as a second messenger for STING activation and triggers TBK1/IRF3 activation, resulting in type I IFN production in human cells. This induction of type I IFN was independent of IFI16. Access of DNA to the cytosolic compartment is mediated by hemozoin, because incubation of purified malaria pigment with DNase abrogated IFN-β induction. Collectively, these observations implicate cGAS as an important cytosolic sensor of P. falciparum genomic DNA and reveal the role of the cGAS/STING pathway in the induction of type I IFN in response to malaria parasites.
A Forcing Axiom Deciding the Generalized Souslin Hypothesis
Authors: Lambie-Hanson Chris , Rinot Assaf 
Published: December 2017

AbstractWe derive a forcing axiom from the conjunction of square and diamond, and present a few applications, primary among them being the existence of super-Souslin trees. It follows that for every uncountable cardinal$\unicode[STIX]{x1D706}$, if$\unicode[STIX]{x1D706}^{++}$is not a Mahlo cardinal in Gödel’s constructible universe, then$2^{\unicode[STIX]{x1D706}}=\unicode[STIX]{x1D706}^{+}$entails the existence of a$\unicode[STIX]{x1D706}^{+}$-complete$\unicode[STIX]{x1D706}^{++}$-Souslin tree.
On the Weak Order of Coxeter Groups
Authors: Dyer Matthew 
Published: December 2017

AbstractThis paper provides some evidence for conjectural relations between extensions of (right) weak order on Coxeter groups, closure operators on root systems, and Bruhat order. The conjecture focused upon here refines an earlier question as to whether the set of initial sections of reflection orders, ordered by inclusion, forms a complete lattice. Meet and join in weak order are described in terms of a suitable closure operator. Galois connections are defined from the power set of $W$ to itself, under which maximal subgroups of certain groupoids correspond to certain complete meet subsemilattices of weak order. An analogue of weak order for standard parabolic subsets of any rank of the root system is defined, reducing to the usual weak order in rank zero, and having some analogous properties in rank one (and conjecturally in general).
Field characterization of the PM2.5 Aerosol Chemical Speciation Monitor: insights into the composition, sources, and processes of fine particles in eastern China
Authors: Zhang Yunjiang , Tang Lili , Croteau Philip L. , Favez Olivier , Sun Yele , Canagaratna Manjula R. , Wang Zhuang , Couvidat Florian , Albinet Alexandre , Zhang Hongliang , Sciare Jean , Prévôt André S. H. , Jayne John T. , Worsnop Douglas R. 
Published: December 2017

Abstract. A PM2.5-capable aerosol chemical speciation monitor (Q-ACSM) was deployed in urban Nanjing, China, for the first time to measure in situ non-refractory fine particle (NR-PM2.5) composition from 20 October to 19 November 2015, along with parallel measurements of submicron aerosol (PM1) species by a standard Q-ACSM. Our results show that the NR-PM2.5 species (organics, sulfate, nitrate, and ammonium) measured by the PM2.5-Q-ACSM are highly correlated (r2 > 0.9) with those measured by a Sunset Lab OC  /  EC analyzer and a Monitor for AeRosols and GAses (MARGA). The comparisons between the two Q-ACSMs illustrated similar temporal variations in all NR species between PM1 and PM2.5, yet substantial mass fractions of aerosol species were observed in the size range of 1–2.5 µm. On average, NR-PM1−2.5 contributed 53 % of the total NR-PM2.5, with sulfate and secondary organic aerosols (SOAs) being the two largest contributors (26 and 27 %, respectively). Positive matrix factorization of organic aerosol showed similar temporal variations in both primary and secondary OAs between PM1 and PM2.5, although the mass spectra were slightly different due to more thermal decomposition on the capture vaporizer of the PM2.5-Q-ACSM. We observed an enhancement of SOA under high relative humidity conditions, which is associated with simultaneous increases in aerosol pH, gas-phase species (NO2, SO2, and NH3) concentrations and aerosol water content driven by secondary inorganic aerosols. These results likely indicate an enhanced reactive uptake of SOA precursors upon aqueous particles. Therefore, reducing anthropogenic NOx, SO2, and NH3 emissions might not only reduce secondary inorganic aerosols but also the SOA burden during haze episodes in China.