bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Dr. Rima Rudd's Organizational Health Literacy Scholarship in Maryland
Authors: Baur Cynthia , Maybury Catherine , Rosenfeld Lindsay , Richey Leah 
Published: September 2024

Background:
This article analyzes and reflects on Dr. Rima Rudd's organizational health literacy ideas and tools and their influence on the field generally and on four projects over 12 years in Maryland specifically.

Objective:
We present four organizational health literacy projects – two from oral health and two from COVID-19 vaccination – that used or were influenced by Dr. Rudd's the Health Literacy Environment of Hospitals and Health Centers.

Methods:
In the oral health projects, we describe the organizational assessments we conducted, the assessment results, and the actions organizations took in response. In a Frederick, Maryland, COVID-19 project, we worked with multiple organizations in a single city to train them in the organizational assessment process, and we report the activities and results of this training. In the Baltimore, Maryland COVID-19 project, we provided general information about organizational health literacy and trained key health professionals in local organizations.

Key Results:
Our results confirm that Dr. Rudd's tools work mainly as intended because they help organizations or third-party evaluators identify health literacy barriers and create health literacy insights. Also, we observed that organizational health literacy tools can support organizations' interest in equity goals and increase their willingness to spend time on health literacy projects.

Conclusions:

Translating knowledge and skills to actions can require more time than organizations can commit or be more difficult than they can handle. In our projects, the four most positive examples were driven by a collaboration between our team and a change champion who had the power to institute new ideas and actions. While it can take time and money to gain traction, our Maryland work shows that organizational assessments are accessible, practical and tangible. We conclude that Dr. Rudd's influence extends beyond specific tools and is reflected in the field's acceptance of organizational and professional responsibility for health literacy as an equity and justice issue. [

HLRP: Health Literacy Research and Practice
. 2024;8(3):e151–e158.

]
The effects of brown rice as functional food on Lee Index, adipose tissues and PRDM16 levels in obesity model <i>Rattus norvegicus</i>
Authors: Pricelia Jeany , Arini Putri Dwi , Alifiyah Hazrina Putri , Syabania Riri , Kusumastuty Inggita , Sulistyowati Etik , Sasiarini Laksmi , Rudijanto Achmad , Handayani Dian 
Published: September 2024

Brown rice is a functional food known to improve the Lee Index, influencing PRDM16 levels in obesity conditions. Therefore, this study aims to determine the differences in Lee Index, Brown Adipose Tissue (BAT) weight, White Adipose Tissue (WAT) weight, BeAT weight, total body fat, and PRDM16 levels of obese model rats with the intervention of brown and white rice, as well as ℽ-oryzanol. A true experimental method was used with a post-test-only control group in vivo design. The obesity model was constructed with male Sprague Dawley rats (Rattus norvegicus), divided into five diet groups namely standard and HFHF diet control, as well as HFHF + brown rice, HFHF + white rice, and HFHF + ℽ-oryzanol combination diet. The experiment was carried out for 26 weeks, with details of 14 weeks to form an obese model and 12 weeks for the intervention. Before statistical correlation was tested, Lee index values, adipose tissues, and PRDM16 were analyzed. The anthropometric data collection method was carried out by weighing before and after the intervention, while adipose tissue was collected by weighing after sacrifice. The immunofluorescence method was used to collect the expression of PRDM16 and the mean of PRDM16 levels was analyzed in the ImageJ application. After the data collection process, analysis was performed using SPSS to determine possible differences in each group. Normally distributed data were analyzed using One-Way ANOVA, while those without normal distribution were assessed using the Kruskall-Walis method and the Mann Whitney-U advanced test, with a p-value of <0.05 considered significantly different.The result showed that there were differences among several groups regarding total body fat (p=0.012), WAT (p=0.026), and BAT (p=0.025). However, no differences were found between all groups regarding the Lee index (p=0.275), BeAT (p=0.079), and PRDM16 level (p=0.292). In conclusion, brown rice intervention did not significantly affect Lee index values, the expression of PRDM16, and adipose tissue weights at the end of the intervention.
Divine ambiguity: A philosophical inquiry into God’s uncertain decisions
Authors: Durodolu Oluwole O. , Ngoepe Mpho 
Published: September 2024

The debate surrounding the nature and attributes of God as presented in the Bible has garnered significant attention and critique from various philosophical perspectives like Friedrich Nietzsche, Bertrand Russell and David Hume. This philosophical critique emphasises the inconsistency in the nature of God and challenges traditional theological beliefs. The expression of regret by the God of the Bible in Genesis 6:6 raises philosophical dilemmas regarding divine attributes and the problem of evil. The contradiction between God’s regret and the affirmation of his creation as good underscores fundamental questions about divine omniscience, omnipotence and benevolence. The presence of evil and suffering in the world poses a significant challenge to the notion of a loving and all-powerful God. Examples of human suffering, such as slavery, colonisation, apartheid and natural disasters, further highlight the complexity of reconciling divine attributes with the existence of evil. Philosophically analysing biblical narratives, such as the story of Job, Noah’s flood and the plagues of Egypt, raises ethical concerns regarding divine justice and the moral agency of humanity. Additionally, the indiscriminate punishment of innocent individuals in these narratives challenges the credibility of a benevolent and compassionate God. The philosophical inquiry into the problem of evil and natural disasters underscores the need for a nuanced understanding of divine attributes and their implications for human existence.Contribution: The study encourages reflection on key questions about the nature of divinity, the morality of divine actions, and the compatibility of traditional theology with rational thought. It highlights how inconsistencies in certain biblical accounts challenge those trying to balance faith with reason and scientific understanding. While some may view these narratives as metaphors or allegories, others find it difficult to align them with their intellectual beliefs, resulting in tensions between religious faith and scientific rationality.
Even a worm will turn: An atypical presentation of hydatid disease
Authors: Saieva Piero , Lovelock Tamsin , Jardine Thabiet 
Published: September 2024

Hydatid disease (cystic echinococcosis) is a neglected zoonosis, often incidentally detected in its late stages. The clinical manifestations depend on the location and dimensions of the cysts, with the liver and lungs frequently affected. This case report describes thrombocytopenia, an unusual haematological complication of hydatid disease. We use this case to highlight the role that platelets play in various parasitic infections and to advocate for further research into the role of platelets in hydatid disease.Contribution: We draw attention to a less well-known complication of hydatid disease.
Risk of thyroid diseases in patients with psoriasis: A systematic review and meta-analysis of cohort studies
Authors: Jiesisibieke Zhu Liduzi , Yang Syue-Mei , Tsai Hsin-Hua , Wang Yen-Chun , Chen Pei-En , Wang Tzu-Yu , Chi Ching-Chi , Tung Tao-Hsin 
Published: September 2024

Abstract

Background:
An autoimmune etiology has been indicated for thyroid diseases. However, few studies have examined the association between psoriasis and thyroid diseases.

Objectives:
Explore the risk of thyroid disease in patients with psoriasis.

Methods:
We conducted a systematic review and meta-analysis of cohort studies to assess the risk of thyroid disease in patients with psoriasis. We searched PubMed, Cochrane Library, and EMBASE from their inception to April 4, 2024. Two authors independently selected the studies, assessed their quality, and extracted the data. Any disagreements were resolved through discussions with a third author. Risk ratio (RR) and 95% confidence intervals (CI) were used to present the results.

Results:
Three cohort studies were included. The risks of thyroiditis (RR: 1.74, 95% CI: 1.23–2.47), hyperthyroidism (RR: 1.22, 95% CI: 1.14–1.32), and hypothyroidism (RR: 1.42, 95% CI: 1.29–1.57) were higher among the patients with psoriasis than those in the control group.

Conclusion:
Individuals with psoriasis have a higher risk of developing thyroid disease. Further studies that provide data on different sex and age groups are needed to clarify whether any specific subgroup of patients with psoriasis has an elevated risk of developing thyroid disease.
Effect of calcium hydroxide and calcium hydroxide nanoparticles used as intracanal drugs after manual and ultrasonic removal on the bond strength of a new sealer with a pozzolan base (Endoseal mineral trioxide aggregate)
Authors: Reyhani Mohammad Frough , Salem-Milani Amin , Janani Maryam , Dogohar Amirhossein , Nazari Leila 
Published: September 2024

ABSTRACT

Aim:
The adhesion ability of filling materials to the root canal wall can be affected by the intracanal medicaments. The present study investigated the effect of pretreatment with nano-calcium hydroxide and calcium hydroxide on the bond strength of Endoseal mineral trioxide aggregate (MTA) to root canal dentin.

Methods:
Fifty maxillary incisor teeth were randomly divided into two experimental groups (n = 20) and a control group (n = 10) after decoronation near the cementoenamel junction and root canal instrumentation according to the type of intracanal medicament (calcium hydroxide and nano-calcium hydroxide). Each experimental group was divided into two subgroups based on manual and ultrasonic drug removal methods. After removing intracanal medicaments and irrigating them, all the groups were obturated with gutta-percha and Endoseal MTA sealer. Then, the samples were sectioned into cross-sections with a thickness of 2 mm using a diamond disc, and the push-out bond strength test was performed on them.

Results:
The results showed no significant difference in the mean Endoseal MTA bond strength in terms of the type of intracanal medicament and the method used to remove it from the canal (P > 0.05).

Conclusion:
Using the ultrasonic method compared to the manual method in removing intracanal medicament resulted in no significant difference in the strength of the Endoseal MTA bond. Furthermore, the effect of nanoparticle calcium hydroxide on Endoseal MTA bond strength was not different compared to the conventional type of this medication.
Self-retentive double-ended suction tip: A new and innovative concept in dentistry
Authors: Rao Ajay Singh , Mavani Harshit Tushar , Pawar Ajinkya M , Shah Nimisha , Solanki Dikshit 
Published: September 2024

ABSTRACT

Aim:
To create an innovative “double-ended and “self-retentive” suction tip that is specifically designed: To provide “dual action; which works under the rubber dam sheet as well above the rubber dam sheet at the same time. Also, to eliminate the need of holding the suction tip (being self-retentive) using a technical tip with which it can be fixed to the rubber dam frame.

Methods:
Three conventional suction tip with a few chair-side equipments are needed to create this innovative suction tip. It’s clinical applications is also very easy and can effortlessly be grasped.

Results:
The “double-ended and “self-retentive” suction tip works efficiently and provides desired level of moisture control.

Conclusion:
This new innovatively created suction device can be easily created chair-side and it can be a solution to provide moisture control “in and out” of the oral cavity.
Histopathological evaluation of geriatric ophthalmic veins: A cadaveric study
Authors: Mehrhoff Farida , Theobalt Keanna G. , Barry Alla G. , Hillard Robert 
Published: September 2024

Context:The ophthalmic vein (OV) has become a source of increasing curiosity since many aspects of vascular surgery of the orbit have become feasible. At the same time, histochemical analysis of veins, in general, tends to skip the OV. Moreover, age-related changes in the OVs remain untouched.Aims:Our research explores features of aging in the OV.Settings and Design:We immunohistochemically evaluated the superior and inferior OVs in 49 orbits of 28 formalin-embalmed human cadavers (age 77.86 ± 13.38) without visible vascular malformations.Materials and Methods:Specimens were stained by hematoxylin and eosin. Verhoeff, laminin, and CD31 stains were used on a subset of the OVs.Statistical Analysis Used:Simple descriptive statistics.Results:The findings include vasa vasorum (VV) in OVs smaller than 0.5 mm, a valvular structure in one of the VV, the presence of platelet endothelial adhesion molecule granules in donors older than 80 years of age, and changes in the pattern of elastin and collagen in different age categories.Conclusion:The study visualizes new aspects in the veins of elderly individuals and reveals OVs’ structures unreported previously.
Sub-Tenon versus peribulbar anesthesia in vitreoretinal surgery: A retrospective analysis in a tertiary eye care center
Authors: Nene Amit S. , Divate Sheetal , Khare Smita , Pirdankar Onkar H. , Badole Pushpanjali , Shenoy Pratik , Quraishi Mohd Azaz , Shah Smitesh 
Published: September 2024

Aim:
The aim of this study was to compare the efficacy of sub-Tenon and peribulbar anesthesia in vitreoretinal surgeries.

Methods:
This was a retrospective study where patients who received peribulbar or sub-Tenon anesthesia during vitreoretinal surgeries between July 2023 and September 2023 were included. Lid movements, subconjunctival hemorrhage, chemosis, and akinesia were evaluated after anesthesia was injected in the two groups. Pain score was evaluated at the time of anesthesia, intraoperatively, and postoperatively after 1 h.

Results:
We included 108 patients, of which 58 were given peribulbar and 50 had sub-Tenon anesthesia and had mean ± standard deviation age of 56.8 ± 12.6 years and 57.90 ± 13.0 years, respectively (P = 0.67). Baseline, intraoperative, and postoperative (at 1 h after surgery) systolic blood pressure (BP), diastolic BP, and pulse rate were similar in both groups. None of the patients had any systemic complications in both the peribulbar and sub-Tenon groups. The mean pain score at postoperative 1 h was similar in both groups (P = 0.58). At postoperative 1 day, two patients had ecchymosis in the peribulbar group. Eighteen cases had lid edema in the peribulbar group compared to no lid edema in the sub-Tenon group (P < 0.001).

Conclusion:
Sub-Tenon anesthesia is a simple, safe, and less traumatic technique that is as good as peribulbar in terms of providing analgesia. Although sub-Tenon could not produce total akinesia in most of the cases, the surgeon was able to operate comfortably with negligible chance of anesthesia-related complications. However, the anesthetist also plays an important role in a multidisciplinary approach in the management of vitreoretinal surgeries.
Genetic Markers of Spina Bifida in an Indian Cohort
Authors: Goel Prabudh , Sharma Mahima , Kaushik Himani , Kumar Sourabh , Singh Harpreet , Jain Vishesh , Dhua Anjan Kumar , Yadav Devendra Kumar , Kumar Neeta , Agarwala Sandeep 
Published: September 2024

ABSTRACT

Objective:
To identify the genetic markers of spina bifida through a systematic survey of the exome in an Indian cohort.

Materials and Methods:
Three consecutive patients (P1: 1 year, male; P2: 2.8 years, male; and P3: 10 years, female) with spina bifida (lumbosacral meningomyelocele) underwent whole-exome sequencing (libraries: SureSelect Human All Exon V8; sequencing: 2 * 150 bp paired-end run, 100×) with NovaSeq 6000. Data analysis was performed using SMART-One™ (secondary analysis) and SMARTer™ (tertiary analysis) for automated quality check, alignment (GRCh38/hg38), variant calling, annotation (ClinVar, OMIM, avsnp150, 1000 Genomes v5b, ExAC v0.3, gnomAD v4.0, and esp6500vi2all v0.0.25), v0.0.25), interpretation. The pathogenic and likely pathogenic (ClinVar/ InterVar), non-synonymous, exonic markers (read depth ≥ 5) were matched with the Familial Neural Tube Defects (Version 1.10) panel (FNTD panel).

Results:
Pathogenic variants overlapping with the FNTD panel were MTRR, CC2D2A, and ZIC2 in P1 and P2, TGIF1 in P1 only, and none in P3. Novel pathogenic/likely pathogenic variants common to all three patients were PRUNE1, PKD1, PDZD2, and DAB2 in the homozygous state as well as in the heterozygous state, PLK1 and NLGN2. The possible role of such markers in etiopathogenesis was explored through a literatur search.

Conclusions:
The genetic landscape of the spina bifida in an Indian cohort is diverse compared to that reported from other parts of the world. A comprehensive catalog of single-nucleotide variants in the etiopathogenesis of the spina bifida on a background of the Familial Neural Tube Defects Panel has been generated.
Can Ultrasound Spot the Culprit – Evaluating the Effectiveness of Ultrasonography in Precisely Diagnosing Acute Appendicitis in Children
Authors: Vig Ayushi , Sinha Arvind , Yadav Taruna , Krishnamurthy Shreyas , Bhatt Somya , Rathod Kirtikumar J. , Pathak Manish , Saxena Rahul , Khera Pushpinder Singh 
Published: September 2024

ABSTRACT

Introduction:
Acute appendicitis is a common surgical emergency in children, often requiring imaging for confirmation due to diverse presentations. While computed tomography scan is favored in many centers for its sensitivity, it comes with radiation exposure and higher costs. Ultrasonography, being radiation-free and cost-effective, is gaining popularity, especially in pediatric cases. However, its reported accuracy varies in the literature. This study aims to evaluate the diagnostic accuracy of ultrasonography in pediatric appendicitis cases and to determine its precision in distinguishing between simple and complicated cases of appendicitis.

Materials and Methods:
A retrospective analysis was conducted on children with suspected appendicitis who presented to the department of pediatric surgery. All patients underwent ultrasonography followed by appendicectomy based on considered clinical decision. Ultrasonography findings were compared with intraoperative observations categorized as uncomplicated or complicated appendicitis.

Results:
Among 152 patients, ultrasonography accurately diagnosed appendicitis in 94.6% of cases, with 5.38% having nonvisualized appendices. In our group, the sensitivity and specificity of ultrasound to detect appendicitis were 94.62% and 95.65%, respectively. The diagnostic accuracy of the test is 95.63%. However, in our study, the sensitivity of the ultrasonography to correctly identify if it is a simple or complicated appendicitis was only 54.9% but had a specificity of 98.7%. Thus, ultrasonography showed a much lower sensitivity (54.9%) in distinguishing between simple and complicated appendicitis.

Conclusion:
Ultrasonography demonstrates high sensitivity and specificity in diagnosing pediatric appendicitis, making it a promising preoperative investigation. However, it may not accurately differentiate between simple and complicated cases. A comprehensive approach involving clinical and laboratory parameters alongside secondary imaging may be necessary for accurate diagnosis, especially in cases of perforated appendicitis.
NeuroPsychophysiological Investigation of ASMR Advertising Experience
Authors: Kence Esil Sonmez , Ülker Selami Varol , Canan Sinan 
Published: September 2024

Aim:
The framework of this research is to examine the effects of autonomous sensory meridian responses (ASMRs) sensory/impulse circularity, psychological infrastructure, and the effects of brand advertisements using this technique on consumer behaviors and physiological outcomes such as product attitude, purchase intention, advertisement taste, and perceived visual advertisement esthetics.

Materials and Methods:
Mixed research method was used in the study, which consisted of consumers with high depressive mood and anxiety level (experimental group) and consumers with low depressive mood and anxiety level (control group). Electrodermal activity measurement and facial reading (facial coding) analysis are two specific neuromarketing research techniques utilized in this research. In addition, consumer attitude scales and psychological scales were employed.

Results:
According to the results obtained from the findings of the study, the physiological and attitudinal effects of ASMR advertisements do not show significant differences between the experimental and control groups. This is due to the fact that ASMR varies from person to person and has an atypical physiological pattern.

Conclusion:
The fact that ASMR is an ambiguous and contradictory experience with different physiological profiles due to factors such as causality, connectivity and relativity is consistent with the findings of this research.
Paralyzed Patients-Oriented Electroencephalogram Signals Processing using Convolutional Neural Network Through Python
Authors: Topuz Vedat , Ayça AK , Boyar Tülin 
Published: September 2024

Aim:
Some of the systems that use brain–computer interfaces (BCIs) that translate brain activity patterns into commands for an interactive application make use of samples produced by motor imagery. This study focuses on processing electroencephalogram (EEG) signals using convolutional neural network (CNN). It is aimed to analyze EEG signals using Python, convert data to spectrogram, and classify them with CNN in this article.

Materials and Methods:
EEG data used were sampled at a sampling frequency of 128 Hz, in the range of 0.5–50 Hz. The EEG file is processed using Python programming language. Spectrogram images of the channels were obtained with the Python YASA library.

Results:
The success of the CNN model applied to dataset was found to be 89.58%.

Conclusion:
EEG signals make it possible to detect diseases using various machine learning methods. Deep learning-based CNN algorithms can also be used for this purpose.