bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influências históricas na abordagem de livros didáticos de matemática
Authors: Cruz Alan Raniel Borges da 
Published: November 2017

O presente artigo objetiva levar o leitor a uma reflexão da prática docente na área de matemática. Para isso, foram buscadas informações históricas sobre a década de 1970 até o presente, tanto em artigos e obras referentes ao período, como analisando livros didáticos de matemática referentes ao espaço de tempo. No total, seis livros didáticos, variando o ano de publicação entre 1971 e 2012. Foram consultados autores como Burigo (1990), D'Ambrósio (2008), DobrovolskI (2009), Iskandar (2002), Kline (1976), Mathias (2012) e Valente (2007), para entender melhor cada momento histórico da matemática no Brasil, tendo o período indicado como referência. Os Parâmetros Curriculares Nacionais (PCNs) de matemática também foram fundamentais para justificar a relação forte entre uma ciência e história. Espera-se que ao final da leitura esteja clara a relação da matemática com sua história, bem como a história do país e ainda, que a educação matemática é dinâmica e acompanha o momento social do país.Palavras Chave: Livro didático. História da matemática. Abordagens contextualizadas.AbstractThis article aims to take the reader to a reflection of mathematics teaching practice. In this purpose, historical information from 1970s to the present was sought, the search was done in articles and works for the period, beyond analyzing textbooks of mathematics related to the time slot, it was a total of six textbooks between the years 1971 and 2012. It was consulted authors as Burigo (1990), D'Ambrósio (2008), DobrovolskI (2009), Iskandar (2002), Kline (1976), Mathias (2012) e Valente (2007), to better understand each historical moment of mathematics in Brazil, having the period set by reference. The National Curriculum Parameters (PCNs) of math were also fundamental to justify the strong relationship between science and history. It is expected that at the end of reading it is clear the relationship of mathematics with its history and the history of the country and also that mathematics education is dynamic and tracks the social moment of the country.Keywords: Textbook. Mathematics’ History. Contextualized Approaches.
Avaliação de Desempenho de Técnicas de Migração de Máquinas Virtuais para o Ambiente de Computação em Nuvem
Authors: Peixoto Maycon Leone , Kuehne Bruno Tardiole , Leite Dionisio M. , Batista Bruno Guazzelli , Costa Danilo , Henrique Carlos , Batista João , Junior Wellington 
Published: November 2017

As ferramentas de virtualização têm um papel fundamental no crescimento da utilização da Computação em Nuvem. Por meio da virtualização, é possível realizar a migração de máquinas virtuais dentro de um provedor de serviços de nuvem, proporcionando a utilização eficiente dos recursos. Entretanto, não oram evidenciadas quais técnicas são mais indicadas de acordo com os cenários distintos de carga no qual o sistema está operando. Diferentemente das avaliações de desempenhos simplesmente comparativas encontradas na literatura, este trabalho propõe a utilização de um modelo estatístico consistente para avaliação de desempenho das técnicas de migração: (i) live migration e (ii) non-live migration. O objetivo do modelo estatístico é identificar o comportamento das técnicas de migração de máquinas virtuais sob diferentes situações de cargas de trabalho. O modelo estatístico proposto para utilização é composto pela abordagem de avaliação de desempenho das técnicas de migração de máquina virtual combinado com o planejamento de experimentos de projeto fatorial 2k.Palavras-chave: Migração. Máquinas Virtuais. Avaliação de Desempenho. AbstractPerformance evaluation of virtual machine migration approaches on cloud computign environment Virtualization tools play a key role in increasing the use of Cloud Computing. Through virtualization, it is possible to migrate virtual machines within a cloud service provider, providing efficient resource utilization. However, there are not evident which techniques work better in according to the different load scenarios in which the system is operating. This work proposes the use of a consistent statistical model to evaluate the performance of migration techniques:(i) live migration and (ii) non-live migration. The objective of the statistical model is to identify the behavior of virtual machine migration techniques under different workload situations. The proposed statistical model for use is based on the performance evaluation approach of the virtual machine migration techniques combined with the 2k factorial design.Keywords: Migration. Performance Evaluation. Virtual Machine.
Uma abordagem no ensino da disciplina de informática e sociedade em um curso de ciência da computação: o relato de uma experiência
Authors: Seabra Rodrigo Duarte 
Published: November 2017

Este trabalho apresenta uma proposta de abordagem no ensino da disciplina de Informática e Sociedade presente nas diretrizes curriculares da maioria dos cursos de Computação e afins. O objeto de estudo refere-se ao curso oferecido aos discentes da Universidade Federal de Itajubá em 2015. O artigo apresenta uma síntese dos principais tópicos debatidos nas aulas, bem como os resultados obtidos com base em uma investigação realizada junto aos discentes, sendo os mais notáveis sumarizados: (i) 96% dos estudantes relataram que a disciplina contribuiu na aquisição de conhecimento relevante para sua futura prática profissional; (ii) os temas informática na educação, regulamentação da profissão de tecnologia da informação, computação verde, computação ubíqua e evolução dos crimes cibernéticos foram os assuntos de maior destaque quanto aos aspectos sociais envolvidos no uso da informática. Palavras-chave: Ciência da computação. Informática e sociedade. Ensino.AbstractAn approach in teaching of the discipline informatics and society in a computer science course: reporting an experienceThis paper presents a proposal for an approach in the teaching of the discipline Informatics and Society, which is present in the curriculum guidelines of most Computing and related courses. The object of study refers to the course offered to students of the Federal University of Itajubá in 2014. The research presents a summary of the main topics discussed in classes as well as the results obtained with basis on an investigation carried out with the students and the most notably summarized: (i) 96% of the students reported that the discipline contributed to the acquisition of relevant knowledge to their future professional practice; (ii) informatics in education issues, regulation of information technology profession, green computing, ubiquitous computing and evolution of cybercrimes were the most prominent themes regarding the social aspects involved in the use of information technology.Keywords: Computer science. Informatics and society. Teaching.
Rede CAN Veicular: levantamento bibliográfico e apresentação de conceitos iniciais
Authors: De Souza Andrey Gustavo , Campos Gustavo Lobato 
Published: November 2017

O objetivo deste trabalho é apresentar as principais características de uma rede CAN veicular, tais como protocolos de camada superiores do modelo OSI, processo de transmissão de mensagens entre unidades no barramento CAN, formato de mensagens, tratamento de erro e também do processo de arbitragem. Uma breve apresentação sobre a rede CAN-FD - a evolução da rede CAN tradicional - é feita levando-se em conta as principais mudanças em relação a sua antecessora. É realizada uma avaliação considerando-se as vantagens do uso da atual tecnologia CAN empregada e os pontos fracos que essa topologia apresenta frente ao cenário do mercado atual, para, dessa forma, avaliar possíveis alternativas.Palavras-chave: Rede CAN. CAN-FD. Redes automotivas. Protocolos de rede.Automotive can network: bibliographical survey and presentation of initial conceptsAbstractThe objective of this document is to present the main features of a vehicular CAN network, such as upper layer protocols of the OSI model, the process of transmission of messages between the nodes in the bus, frame format, the error treatment and the priority arbitration of messages. A brief presentation about CAN-FD network, the evolution of traditional CAN network, is done considering the major changes from its predecessor. An evaluation is performed considering the advantages of its use and the weak features that this topology presents, considering the current market scenario, to thereby evaluate possible alternatives.Keywords: CAN Network. CAN-FD. Automotive networks. Network protocols.
La transparencia sobre sostenibilidad en gobiernos regionales: el caso de España
Authors: Alcaraz-Quiles Francisco J. , Navarro-Galera Andrés , Ortiz-Rodríguez David 
Published: November 2017

En el actual contexto de crisis, los ciudadanos demandan al sector público mayor transparencia y rendición de cuentas. Este trabajo pretende avanzar en el conocimiento de las prácticas de sostenibilidad en la administración pública. Para ello proponemos comparar la divulgación de información sobre sostenibilidad realizada por distintos gobiernos regionales, analizando las webs de los mismos mediante un análisis de contenido, usando para ello un listado de ítems basado en las guías del Global Reporting Initiative (GRI).
Nuestros resultados muestran que los gobiernos regionales españoles difunden dos tercios de la información requerida por el GRI, presentando la información social un nivel de respuesta mayor y la información general un menor nivel de difusión. Además, aquellos gobiernos regionales con mayor compromiso ambiental publican más información sobre sostenibilidad. De nuestras conclusiones podemos destacar que la mala situación financiera que atraviesan no parece impulsar a los gobiernos regionales españoles a divulgar información sobre sostenibilidad.
Le sujet en lieu sûr
Authors: Vallet-Armellino Marion 
Published: November 2017

Les safe-spaces sont des lieux inclusifs où les étudiants américains font l’expérience d’un collectif sécurisant où vivre sa différence, où toute agression verbale serait bannie. Accusés d’infantiliser les esprits et d’affaiblir la liberté d’expression, ils sont au cœur des cultural wars . Ces demandes de protection montrent pourtant à quelles oppressions les minorités sont encore soumises. Dans ces espaces transitionnels, des identités individuelles et groupales s’affirment et rendent visibles leurs combats. De quelle histoire militante proviennent-ils et à quel type d’anxiété répondent-ils ? Formes de (re)prise de pouvoir devant l’hostilité vécue, ces espaces sont sources d’apaisement et transformation. Dans certaines psychothérapies, on se met aussi à l’abri du monde et de ses projections pour trouver sa parole et sa place.
Age-based and reproductive biology of the Pacific Longnose Parrotfish Hipposcarus longiceps from Guam
Authors: Taylor Brett M. , Cruz Eric 
Published: November 2017

The Pacific longnose parrotfish Hipposcarus longiceps (Valenciennes 1840) represents a prime fishery resource throughout much of the tropical Pacific. In this study, we sampled the species from the Guam commercial fishery market across five consecutive years to characterize reproductive and age-based demographic information imperative for informed fishery management. Compared with other parrotfishes, this species was found to be large-bodied, but has only a moderate life span of 10 + years. Hipposcarus longiceps was confirmed as a diandric protogynous hermaphrodite with highly sex-specific growth patterns and an overall mean asymptotic length of 434 mm fork length (FL). Females were estimated to reach median maturity at 329 mm FL (2.4 years) and have a median length at female-to-male sex change of 401 mm FL. Life-history trait values derived here were used to update previous models relating life history and vulnerability to overexploitation. We found that enhancement of just one species’ trait values improved model fits considerably, which strengthens the conclusion that life-history traits are a strong determinant of species’ vulnerability in the parrotfishes. This information is an imperative complement to other data sources facilitating formal stock assessment of a key fishery target.
Severe Mental Retardation Patient With a De Novo Chromosomal Deletion 5q14-22 Can Be a Carrier of a Rectal And Duodenal Cancer Associated With Over 200 Colorectal Polyps: A Case Report
Authors: Sonoda Hiromichi , Shimizu Tomoharu , Miyake Toru , Ohta Hiroyuki , Akabori Hiroya , Tani Masaji 
Published: November 2017

Introduction
Familial adenomatous polyposis (FAP) caused by a de novo 5q chromosomal deletion is rare, and precise cytogenetic analysis using comparative genomic hybridization (CGH) arrays have been performed in a few cases.

Case presentation
We herein present the case of a 38-year-old man with advanced rectal and duodenal cancer, FAP, and severe mental retardation caused by a de novo chromosomal deletion at 5q14–22. He was referred to our outpatient clinic because of a positive fecal occult blood test result. He was found to have advanced rectal cancer, with over 200 colorectal polyps, and duodenal cancer. He underwent laparoscopic total proctocolectomy with definitive ileostomy followed by partial resection of the duodenum. Comparative genomic hybridization to characterize deleted genes identified a large 5q deletion expanding approximately 24.9 Mbp, including the APC gene.

Conclusion
Patients who harbor a chromosomal deletion involving 5q21 are at risk of developing rectal cancer and polyposis. Therefore, such patients need early cancer screening following the availability of genetic information.
MAPK inhibitors induce serine peptidase inhibitor Kazal type 1 (SPINK1) secretion in BRAF V600E‐mutant colorectal adenocarcinoma
Authors: Räsänen Kati , Dang Kien X. , Mustonen Harri , Ho Tho H. , Lintula Susanna , Koistinen Hannu , Stenman Ulf‐Håkan , Haglund Caj , Stenman Jakob 
Published: November 2017

The mitogen‐activated protein kinase (MAPK) pathway plays a central role in colorectal cancers (CRC). In particular, BRAF V600E‐mutant tumors, which represent around 10% of CRCs, are refractory to current therapies. Overexpression and secretion of serine peptidase inhibitor Kazal type 1 (SPINK1) are observed in around 50% of CRCs, and its serum level can be used as a biomarker for poor prognosis. Utilizing a recently developed extendable blocking probe assay, we analyzed the BRAF mutation status in a CRC patient cohort (N = 571) using tissue‐derived RNA as the starting material. From the same RNA samples, we measured the relative SPINK1 expression levels using a quantitative real‐time PCR method. Expression of mutant BRAF V600E correlated with poor prognosis, as did low expression of SPINK1 mRNA. Further, BRAF V600E correlated negatively with SPINK1 levels. In order to investigate the effect of MAPK pathway‐targeted therapies on SPINK1 secretion, we conducted in vitro studies using both wild‐type and V600E CRC cell lines. BRAF inhibitor vemurafenib, and subsequent MAPK pathway inhibitors trametinib and SCH772984, significantly increased SPINK1 secretion in V600E CRC cell lines Colo205 and HT‐29 with a concomitant decrease in trypsin‐1 and ‐2 secretion. Notably, no SPINK1 increase or trypsin‐1 decrease was observed in BRAF wild‐type CRC cell line Caco‐2 in response to MAPK pathway inhibitors. In further mechanistic studies, we observed that only trametinib was able to diminish completely both MEK and ERK phosphorylation in the V600E CRC cells. Furthermore, the key regulator of integrated stress response, activating transcription factor 4 (ATF‐4), was downregulated both at mRNA and at protein level in response to trametinib treatment. In conclusion, these data suggest that sustained inhibition of not only MAPK pathway activation, but also ATF‐4 and trypsin, might be beneficial in the therapy of BRAF V600E‐mutant CRC and that SPINK1 levels may serve as an indicator of therapy response.
Osteology and Radiological Anatomy of the Thoracic Limbs of Temminck's Ground Pangolin (Smutsia temminckii)
Authors: Steyn Christine , Soley John T. , Crole Martina R. 
Published: November 2017

ABSTRACTTemminck's ground pangolin is the only pangolin present in South Africa. It is a myrmecophagous mammal with a bipedal gait. The thoracic limbs are used to break open ant nests, dig for food, and expand previously occupied burrows. This study describes the osteology and radiological anatomy of the thoracic limbs of this threatened species. Thoracic limbs from four Temminck's ground pangolins, which succumbed from electrocution or natural causes, were digitally radiographed in situ. The individual bones were then cleaned, described and digitally radiographed. The skeleton of the thoracic limbs revealed a similar number and arrangement of bones compared to that of domestic carnivores. The bones were robust and displayed numerous open epiphyseal lines. The latter provide an estimate of sexual maturity and should not be confused with fractures in injured ground pangolins. The scapula was broad and triangular‐shaped. The humerus displayed a massive medial epicondyle. The radius and ulna were similarly sized, and displayed a broad radial trochlea and large olecranon tuber, respectively. The manus was composed of seven carpal bones, five short metacarpal bones and five digits of which the three central digits were the best developed. The unguicular process of the distal phalanx was bifid and elongated. The osteological characteristics indicate that the thoracic limbs of Temminck's ground pangolin are specifically adapted for protraction and retraction, strong elbow extension, flexion of the carpus and digits as well as pronation and supination of the antebrachium, as opposed to weight‐bearing. These functions are likewise documented for other scratch‐digging species. Anat Rec, 301:624–635, 2018. © 2017 Wiley Periodicals, Inc.
Higher Coronary Plaque Burden in Psoriatic Arthritis Is Independent of Metabolic Syndrome and Associated With Underlying Disease Severity
Authors: Szentpetery Agnes , Healy Gerard M. , Brady Darragh , Haroon Muhammad , Gallagher Phil , Redmond Ciaran E. , Fleming Hannah , Duignan John , Dodd Jonathan D. , FitzGerald Oliver 
Published: November 2017

ObjectiveTo examine the effect of metabolic syndrome and psoriatic disease–related variables on coronary plaque burden in psoriatic arthritis (PsA) patients.MethodsFifty PsA patients without symptoms of coronary artery disease (CAD) (25 with metabolic syndrome and 25 without metabolic syndrome) and 50 age‐ and sex‐matched controls underwent 64‐slice coronary computed tomography angiography. Plaque localization, segment involvement score (SIS), segment stenosis score (SSS), and total plaque volume (TPV) were calculated. Plaques were classified as calcified, mixed, or noncalcified. Kruskal‐Wallis test, rank correlations, and linear regression analyses were used to study the relationship between PsA, metabolic syndrome, and plaque burden.ResultsPlaques were found in 76% of PsA patients versus 44% of controls (P = 0.001), and a higher proportion of patients with PsA had affected coronary vessels (P = 0.007). SIS, SSS, and TPV were greater in PsA patients than controls (P = 0.003, P = 0.001, and P ≤ 0.001, respectively). More PsA patients had mixed plaques, and mixed plaque volume was higher than in controls (P < 0.001). PsA patients with metabolic syndrome and those without metabolic syndrome had similar plaque burdens and types. SIS, SSS, and TPV did not show significant relationships with features of metabolic syndrome, but did significantly correlate with disease activity measures. TPV was associated with a diagnosis of PsA (B = 0.865, P = 0.008), but not with metabolic syndrome. Age, highest C‐reactive protein level, highest swollen joint count, disease duration, and plasma glucose level were independent predictors of higher plaque burden in PsA.ConclusionPsA is associated with accelerated coronary plaque formation, particularly mixed plaques, independent of metabolic disease. Psoriatic disease activity and severity may predict coronary plaque burden better than traditional risk factors.
Robust Tracking Control and Stabilization of Underactuated Ships
Authors: Li Jia‐Wang 
Published: November 2017

AbstractThis paper addresses the problem of tracking control and stabilization for underactuated ships subjected to parametric modeling uncertainties. By designing a novel error state transformation scheme, some auxiliary variables are provided to be regarded as additional virtual control signals, while these variables can change their structures for different reference trajectories. Then, a robust control scheme is presented to achieve practical convergence of tracking errors and the ship's velocities to bounded neighborhoods of the origin. Simulation results are performed to illustrate the effectiveness of the proposed control scheme.
Integration of a faculty's ongoing research into an undergraduate laboratory teaching class in developmental biology
Authors: Nam Sang‐Chul 
Published: November 2017

AbstractTraditional developmental biology laboratory classes have utilized a number of different model organisms to allow students to be exposed to diverse biological phenomena in developing organisms. This traditional approach has mainly focused on the diverse morphological and anatomical descriptions of the developing organisms. However, modern developmental biology is focusing more on conserved genetic networks which are responsible for generating conserved body patterns in developing organisms. Therefore, it is necessary to develop a new pedagogical tool to educate undergraduate biology students in the laboratory class of developmental biology with the genetic principles which are responsible for generating and controlling the developing body patterns. A new undergraduate laboratory class for developmental biology was developed in order to offer students the opportunity to explore a wide range of experimental procedures, also incorporating the instructor's on‐going research. Thereby the course can serve as a bridge between research and education by combining both into a single theme. The course design involves a sequence of exercises which can be easily adapted to the faculty's ongoing research. This style of laboratory coursework could be a transitional form between a regular laboratory course and a discovery‐based laboratory course. © 2017 by The International Union of Biochemistry and Molecular Biology, 46(2):141–150, 2018.
Acute fatty liver of pregnancy simulating liver tumor
Authors: Anon Benjamin , Scotto Béatrice , Bacq Yannick 
Published: November 2017

Key Clinical MessageAcute fatty liver of pregnancy (AFLP) is a rare liver disease unique to pregnancy that can lead to acute liver failure. Clinicians must have a high index of suspicion for AFLP because only early diagnosis and prompt delivery improve maternal and fetal prognosis.
Fe/Fe3C Nanoparticles Embedded in Nitrogen‐Doped Carbon Nanotubes as Multifunctional Electrocatalysts for Oxygen Catalysis and CO2 Reduction
Authors: Jia Jingchun , Yang Huijuan , Wang Genxiang , Huang Peng , Cai Pingwei , Wen Zhenhai 
Published: November 2017

AbstractHybrids of Fe/Fe3C embedded in N‐doped carbon nanotubes (Fe/Fe3C@NCNTs) are prepared by pyrolyzing mixtures of Fe3O4 nanoparticles and dicyandiamide. The systematic electrochemical study of Fe/Fe3C@NCNTs shows a decent catalytic activity toward the oxygen evolution reaction (OER) and the oxygen reduction reaction (ORR). The sample of Fe/Fe3C@NCNTs at 750 °C exhibits a remarkably high activity with an onset potential of 1.47 V for the OER, and an onset potential of 0.96 V and half‐wave potential 0.88 V for the ORR, which inspired us to set up a rechargeable Zn‐air battery with such Fe/Fe3C@NCNT nanohybrids as the cathode materials, showing a maximum power density of 198 mW cm−2 and long‐term stability after 500 cycles. We also demonstrate that Fe/Fe3C@NCNTs present favorable electrocatalytic activity towards the CO2 reduction reaction (CO2RR) with a low onset potential and good selectivity. The major products are a mixture of H2 and CO gases that can be used for methanol production in the Fischer−Tropsch process.