bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supporting the investigation of health outcomes due to airborne emission by different approaches: current evidence for the waste incineration sector
Authors: Di Maria Francesco , Sisani Federico , Cesari Daniela , Bontempi Elza 
Published: September 2024

AbstractLife cycle assessment (LCA) along with a survey on epidemiologic and oxidative potential studies was used for analysing the current evidence of the impact of airborne emissions from municipal solid waste incineration (MSWI) on human health. The correspondence among investigated health outcomes and pollutants was discussed based on the Chemical Abstract Service (CAS) and the International Agency for Research on Cancer (IARC). LCA indicated the ability of MSWI in avoiding human health impact, about − 2 × 10−4 DALY/tonne together with avoided emissions of particulate matter (PM) and resource depletion, about − 2.5 × 10−3 kg Sbeq/tonne and about − 0.11 kg PM2.5 eq/tonne, respectively. Positive emissions were detected for greenhouses (about 900 kg CO2eq/tonne) and ecotoxicity (about 15,000 CTUe/tonne). Epidemiologic studies performed on population exposed to MSWI reported quite contrasting results. In some of these, hazard ratio (HR) ranging from about 0.7 to 2.2 was reported concerning the incidence of stomach, liver, breast and bladder cancer. Larger agreement was detected concerning the incidence of larynx and lung cancer with HR ranging from about 1 to about 2.6. Direct causal nexuses were not definitively identified. Oxidative potential of PM was characterized by a high Pearson correlation > 0.8 to the presence of CrVI, Cu and Zn. These heavy metals were also identified by both CAS and IARC as toxic (i.e. Cu and Zn) and cancerous (i.e. CrVI) substances affecting the organs of both respiratory and digestive apparatus. In general, even if more research is necessary, LCA, oxidative potential and the epidemiologic survey results showed a high level of accordance. This suggests their integrated exploitation for supporting the investigation of both direct and indirect consequences on environment and health related to waste incineration for both retrospective and predictive studies.
The effect of industrial and urban dust pollution on the ecophysiology and leaf element concentration of Tilia cordata Mill.
Authors: Bierza Karolina , Bierza Wojciech 
Published: September 2024

AbstractThe influences of airborne trace elements in urban dust on element concentrations and functional traits of Tilia cordata were examined. For the present study, the unwashed and washed leaves of T. cordata were collected to assess the concentration of metals in Katowice City, Poland, from sites of different traffic intensity and industry activity. The content of Al, Cd, Cr, Cu, Fe, Mn, Pb, Zn, C, and N was measured. Additionally, a number of functional traits such as photosynthetic pigment content, specific leaf area (SLA), leaf dry matter content (LDMC), and diseased areas of the leaves were determined to assess the impact of the polluters on the physiology of the trees and their resources acquisition strategy. We hypothesized that the photosynthetic pigments of T. cordata will decrease with the traffic and industry intensity, and the traits related to the resources acquisition and stress resistance will shift into a more conservative strategy. The Principal Component Analysis and the Inverse Distance Weighting (IDW) interpolation method helped to identify that the Fe, Zn, Al, and Cr were related mainly to traffic intensification and Pb to industrial activities. The results indicate that Katowice is considerably polluted by Zn (up to 189.6 and 260.2 mg kg−1 in washed and unwashed leaves, respectively), Pb (up to 51.7 and 133.6 mg kg−1), and Cd (up to 2.27 and 2.43 mg kg−1) compared to other cities worldwide. Also, a reduction of approximately 27% in the photosynthetic pigments was observed at the high-traffic and industrial sites. The trees from the mainly affected areas with heavy traffic and industry tend to apply a conservative resources strategy with a decrement in SLA and an increment in LDMC. In contrast, the opposite trend was observed at the less affected sites (high SLA, low LDMC). The study showed that unfavourable urban conditions can trigger a plastic response on multiple levels. Knowledge of the possible paths of adaptation to urban conditions of different plant species is nowadays crucial to appropriate urban greenery planning.
Synergistic Effects of Hydroxychloride and Organic Zinc on Performance, Carcass Characteristics, Liver and Tibia Mineral Profiles of Broiler Chickens
Authors: Sadr Vahideh , Nguyen Hoai Thi Thanh , Pineda Lane , Han Yanming , Toghyani Mehdi 
Published: September 2024

AbstractThis study investigated the potential synergism between hydroxychloride and organic zinc (Zn) at different levels on performance and carcass characteristics of broiler chickens. There were seven experimental diets including a negative control diet without any supplemental Zn, and six diets with 80 mg/kg added Zn in the forms of ZnSO4, hydroxychloride Zn (HCZ) and organic Zn (ORZ), and a combination of HCZ and ORZ at 40 mg/kg HCZ + 40 mg/kg ORZ (HCZ40-ORZ40), 55 mg/kg HCZ + 25 mg/kg ORZ (HCZ55-ORZ25), and 70 mg/kg HCZ + 10 mg/kg ORZ (HCZ70-ORZ10). Each diet was replicated eight times with 17 chicks per replicate. On day 35, HCZ70-ORZ10 and HCZ40-ORZ40 diets resulted in the highest body weights (P < 0.05). Throughout the entire production period (1–35 days), all HCZ and ORZ diets significantly improved feed conversion ratio (FCR) compared to PC (P < 0.05), with HCZ40-ORZ40 showing the lowest FCR. Breast meat yield was lower in NC-fed birds, while HCZ80 and HCZ70-ORZ10 groups had the lowest abdominal fat weight (P < 0.05). Liver and gizzard weight, tibia breaking strength, and ash percentage, footpad dermatitis, and hock burns were not affected. Tibia Zn content was higher in HCZ or ORZ-supplemented birds compared to NC (P < 0.05), whereas other minerals in tibia and liver were unaffected. In summary, the absence of supplemental Zn negatively affects growth and carcass characteristics, whereas replacing ZnSO4 with HCZ, ORZ, or their combinations improves bodyweight and FCR. HCZ70-ORZ10 and HCZ40-ORZ40 were identified as optimal combinations for maximizing feed efficiency.
Postmortem CT and autopsy findings in an elevator-related death: a case report
Authors: Aulino Giovanni , Rega Michele , Rossi Vittoria , Zedda Massimo , Oliva Antonio 
Published: September 2024

AbstractElevator-related fatalities and injuries are rarely discussed. Falls have been identified as the first cause of mortality in the majority of these accidents. Evidence suggests that many elevator accidents may be attributed to inadequate equipment maintenance or malfunctions of the devices. This study examines a case involving an elevator maintenance worker found within an elevator shaft, using postmortem computed tomography (PMCT) along with a full autopsy. The autopsy revealed that the cause of death was severe polytrauma resulting from dragging, compression, and crushing mechanisms, which resulted in a dislocated skull and multiple thoraco-abdominal injuries, including exposed organs and viscera. Detailed examination identified a cranio-encephalic crush, leading to a significant alteration in the physiognomy of the facial structures. Additionally, PMCT revealed complex spinal fractures, such as a Jefferson fracture and a complete Chance fracture at the D6 vertebra, accompanied by spinal deviation proximal to the fracture site. Autopsy findings corroborated these PMCT results. A multidisciplinary approach, including PMCT, is proposed as a strategic method for the comprehensive reconstruction of such accidents, facilitating the collection of extensive data.
The role of molecular biomarkers in recurrent glioblastoma trials: an assessment of the current trial landscape of genome-driven oncology
Authors: van Opijnen Mark P. , de Vos Filip Y. F. , Cuppen Edwin , Geurts Marjolein , Maas Sybren L. N. , Broekman Marike L. D. 
Published: September 2024

AbstractFor glioblastoma patients, the efficacy-targeted therapy is limited to date. Most of the molecular therapies previously studied are lacking efficacy in this population. More trials are needed to study the actual actionability of biomarkers in (recurrent) glioblastoma. This study aimed to assess the current clinical trial landscape to assess the role of molecular biomarkers in trials on recurrent glioblastoma treatment. The database ClinicalTrials.gov was used to identify not yet completed clinical trials on recurrent glioblastoma in adults. Recruiting studies were assessed to investigate the role of molecular criteria, which were retrieved as detailed as possible. Primary outcome was molecular criteria used as selection criteria for study participation. Next to this, details on moment and method of testing, and targets and drugs studied, were collected. In 76% (181/237) of the included studies, molecular criteria were not included in the study design. Of the remaining 56 studies, at least one specific genomic alteration as selection criterium for study participation was required in 33 (59%) studies. Alterations in EGFR, CDKN2A/B or C, CDK4/6, and RB were most frequently investigated, as were the corresponding drugs abemaciclib and ribociclib. Of the immunotherapies, CAR-T therapies were the most frequently studied therapies. Previously, genomics studies have revealed the presence of potentially actionable alterations in glioblastoma. Our study shows that the potential efficacy of targeted treatment is currently not translated into genome-driven trials in patients with recurrent glioblastoma. An intensification of genome-driven trials might help in providing evidence for (in)efficacy of targeted treatments.
Neurotropic Murine β-Coronavirus Infection Causes Differential Expression of Connexin 47 in Oligodendrocyte Subpopulations Associated with Demyelination
Authors: Das Soubhik , Shaw Archana Kumari , Das Sarma Subhajit , Koval Michael , Das Sarma Jayasri , Maulik Mahua 
Published: September 2024

Abstract
Gap junctions (GJs) play a crucial role in the survival of oligodendrocytes and myelination of the central nervous system (CNS). In this study, we investigated the spatiotemporal changes in the expression of oligodendroglial GJ protein connexin 47 (Cx47), its primary astroglial coupling partner, Cx43, and their association with demyelination following intracerebral infection with mouse hepatitis virus (MHV). Neurotropic strains of MHV, a β-coronavirus, induce an acute encephalomyelitis followed by a chronic demyelinating disease that shares similarities with the human disease multiple sclerosis (MS). Our results reveal that Cx47 GJs are persistently lost in mature oligodendrocytes, not only in demyelinating lesions but also in surrounding normal appearing white and gray matter areas, following an initial loss of astroglial Cx43 GJs during acute infection. At later stages after viral clearance, astroglial Cx43 GJs re-emerge but mature oligodendrocytes fail to fully re-establish GJs with astrocytes due to lack of Cx47 GJ expression. In contrast, at this later demyelinating stage, the increased oligodendrocyte precursor cells appear to exhibit Cx47 GJs. Our findings further highlight varying degrees of demyelination in distinct spinal cord regions, with the thoracic cord showing the most pronounced demyelination. The regional difference in demyelination correlates well with dynamic changes in the proportion of different oligodendrocyte lineage cells exhibiting differential Cx47 GJ expression, suggesting an important mechanism of progressive demyelination even after viral clearance.
The left side of gestures: left perceptual bias for meaningless hand gestures recognition is independent from handedness
Authors: Gobbo Silvia , Pavia Jennifer , Proietti Morgana , Primativo Silvia , Arduino Lisa S. , Martelli Marialuisa , Capirci Olga , Daini Roberta 
Published: September 2024

AbstractThe “Left Perceptual Bias” (LPB) is the effect for which the left side of a picture such as a face is used to a greater extent than its right side as shown in a wide variety of experimental tasks. This effect has been observed for faces, body parts and objects. The present work investigated the presence of a LPB in recognizing hand gestures in two experiments. The role of the side of stimuli presentation (left /right), stimuli orientation (palm/back), participants’ handedness and gender were analyzed. Participants were presented with images of meaningless gestures performed by an actor with the right or left hand, from a palm or a back view. Immediately afterward, participants were shown a drawing and had to discriminate whether it represented the same gesture or not. In the first experiment, the task was administered to a sample of right-handed participants, half males. Results showed shorter response times for stimuli presented on the left side and for those shown from the palm. No gender differences were observed. The second experiment included a sample of left-handed participants and the LPB was replicated. Taken together, our results suggest an interpretation of the bias in terms of asymmetries in perceptual processing rather than the involvement of motor representations.
Disparities in Musculoskeletal Oncology
Authors: Koons Abigail , Smith Elyse , Stephens Jeffrey C. , McKnight Natilyn H. , Barr Jennifer , Ibe Izuchukwu K. 
Published: September 2024

Abstract
Purpose of Review
Disparities within the healthcare system serve as barriers to care that lead to poor outcomes for patients. These healthcare disparities are present in all facets of medicine and extend to musculoskeletal oncology care. There are various tenets to health disparities with some factors being modifiable and non-modifiable. The factors play a direct role in a patient’s access to care, time of presentation, poor social determinants of health, outcomes and survival.

Recent Findings
In musculoskeletal oncologic care, factors such as race, socioeconomic factors and insurance status are correlated to advanced disease upon presentation and poor survival for patients with a sarcoma diagnosis. These factors complicate the proper delivery of coordinated care that is required for optimizing patient outcomes.

Summary
Healthcare disparities lead to suboptimal outcomes for patients who require musculoskeletal oncologic care in the short and long term. More research is required to identify ways to address the known modifiable and non-modifiable factors to improve patient outcome.
Randvoorwaarden voor een waardevolle bijdrage van de school aan een gezonder gewicht van kinderen
Authors: Hahnraths Marla T. H. , Dijkstra S. Coosje , Busch Vincent , Verhoeff Arnoud P. , van Engelen Bo H. W. , Winkens Bjorn , Seidell Jaap C. , van Schayck Onno C. P. 
Published: September 2024

SamenvattingStimulering van een gezonde leefstijl tijdens de kindertijd is essentieel voor korte- en langetermijngezondheidswinst. Interventies zoals Jump-In en de Gezonde Basisschool van de Toekomst laten positieve gezondheidseffecten zien. Maar wat is er nodig om deze structureel te integreren in de basisschoolomgeving? We beschrijven in dit artikel randvoorwaarden die het belang van een systeembenadering benadrukken. Een coherent pakket aan maatregelen is nodig zodat structurele gezondheidsbevordering op scholen een logisch gevolg is van een gezond systeem. In combinatie met een gezonde thuisomgeving, sportomgeving en openbare ruimte kan de schoolomgeving een positieve en duurzame impact hebben op de gezondheid van kinderen.
The effects of market-oriented farming on living standards, nutrition, and informal sharing arrangements of smallholder farmers: the case of African indigenous vegetables in Kenya
Authors: Kubitza Christoph , Hackfort Sarah , Opiyo Arnold , Rauh Cornelia , Stokes Caroline S. , Huyskens-Keil Susanne 
Published: September 2024

AbstractThe shift from subsistence to more market-oriented agriculture is viewed as essential to increase smallholder farmers’ welfare. However, its impact on farmers’ nutrition and informal sharing arrangements and associated solidarity within African farming communities remains uncertain. To analyse these trade-offs, we study the growing commercialization of African indigenous vegetables (AIV) in Kenya. These vegetables are an essential component of local diets in rural areas but also of informal sharing arrangements that provide access to food outside of markets. This article combines quantitative data from a 2016–2022 panel survey of farmers with qualitative data from focus group discussions. Results based on household fixed-effects models show a significant increase in households’ non-food expenditures due to selling AIV. The results suggest that selling AIV did not negatively affect nutrition outcomes but did not improve them either. Informal AIV sharing between households decreased further with growing market participation. Panel data models indicate, however, inconsistent and insignificant changes in associated solidarity indicators. We attribute this to the multiple and sometimes opposing effects of market-oriented farming on solidarity, as revealed by focus group discussions. While some farmers perceive reduced solidarity due to less informal AIV sharing, others perceived this traditional solidarity to be partially forced. Other forms of social interaction have also emerged, such as cooperatives and more intensive knowledge sharing. Despite concerns about the loss of informal sharing and community solidarity and limited improvements in nutrition outcomes, the tangible income gains generated by selling AIV are likely to foster further growth in the AIV sector.
The role of fault pathways for modern and deep recharge to a semi-confined aquifer: revised analysis of modern water leakage pathways in the Davis wellfield, Memphis, Tennessee, USA
Authors: Towell J. , Larsen D. , Schoefernacker S. , Waldron B. , Villalpando-Vizcaino R. , Leslie D. 
Published: September 2024

AbstractHydrologic tracer, borehole log and geophysical data provide new insight into recharge sources and pathways to the semi-confined Memphis aquifer in the Davis wellfield, Memphis, Tennessee, U.S.A. New data and recent studies highlight the importance of faults as potential pathways for the migration of modern water into the Memphis aquifer, an important regional public, industrial, and agricultural water supply. Geochemical and environmental tracer data collected over the past 28 years, combined with hydrologic, stratigraphic, and structural data, were used to evaluate changes in water quality and different recharge pathways to the Memphis aquifer. Assessment of stratigraphic and structural relationships argue for the wellfield being bound by a fault along the bluff line (west) and another fault or faults along the eastern and southeastern margins. Modern water recharge (< 60 years old) occurs through the fault along the western boundary of the wellfield, whereas modern water and, seasonally, deep-seated (helium-bearing) fluids recharge along the fault on the southeastern margin. Each recharge source and pathway present different vulnerabilities, suggesting that the role of faults in wellfields within active tectonic regions needs to be assessed.
Can dry rivers provide a good quality of life? Integrating beneficial and detrimental nature’s contributions to people over time
Authors: Nicolás-Ruiz Néstor , Suárez María Luisa , Vidal-Abarca María Rosario , Quintas-Soriano Cristina 
Published: September 2024

AbstractAlthough dry rivers only flow after heavy rainfall, recent studies have evidenced that they provide benefits to people. However, part of society undervalues these benefits, raising the question of whether they contribute to a good quality of life (GQL). We hypothesised that the benefits of dry rivers contribute to GQL of local communities as long as these benefits are not altered by human disturbance. Local communities closely associated with three dry rivers in Murcia (Spain) were interviewed. The relationships between benefits and GQL, and between detriments and GQL were described. Different benefits and detriments have different impacts on GQL dimensions. Social perceptions of the contribution of benefits and detriments to GQL vary between communities and individuals, and change over time. This implies the development of social studies to ensure inclusive management. Incorporating detriment co-production into research can raise people’s awareness of the role that human activities play in maintaining GQL.
Semi-Riemannian structures for symmetric Galilean spacetimes
Authors: de la Fuente Daniel , Pelegrín José A. S. , Rubio Rafael M. 
Published: September 2024

AbstractWe introduce semi-Riemannian structures well-adapted to certain fields of observers in a Galilean spacetime. The Levi-Civita connection of such a semi-Riemannian metric will allow us to obtain variational characterizations of the Galilean geodesics as well as global results on the topological and differentiable structure of the spacetime. Moreover, these new semi-Riemannian metrics provide a new way to compare the studied Newton–Cartan models with their relativistic counterparts.
Bicycle Set-Up Dimensions and Cycling Kinematics: A Consensus Statement Using Delphi Methodology
Authors: Priego-Quesada Jose Ignacio , Arkesteijn Marco , Bertucci William , Bini Rodrigo R. , Carpes Felipe P. , Diefenthaeler Fernando , Dorel Sylvain , Fonda Borut , Gatti Anthony A. , Holliday Wendy , Janssen Ina , Elvira Jose L. López , Millour Geoffrey , Perez-Soriano Pedro , Swart Jeroen , Visentini Paul , Zhang Songning , Encarnación-Martínez Alberto 
Published: September 2024

AbstractBicycle set-up dimensions and cycling kinematic data are important components of bicycle fitting and cyclist testing protocols. However, there are no guidelines on how bicycles should be measured and how kinematic data should be collected to increase the reliability of outcomes. This article proposes a consensus regarding bicycle set-up dimensions and recommendations for collecting cycling-related kinematic data. Four core members recruited panellists, prepared the document to review in each round for panellists, analysed the scores and comments of the expert panellists, reported the decisions and communicated with panellists. Fourteen experts with experience in research involving cycling kinematics and/or bicycle fitting agreed to participate as panellists. An initial list of 17 statements was proposed, rated using a five-point Likert scale and commented on by panellists in three rounds of anonymous surveys following a Delphi procedure. The consensus was agreed upon when more than 80% of the panellists scored the statement with values of 4 and 5 (moderately and strongly agree) with an interquartile range of less than or equal to 1. A consensus was achieved for eight statements addressing bicycle set-up dimensions (e.g. saddle height, saddle setback, etc.) and nine statements for cycling kinematic assessment (e.g. kinematic method, two-dimensional methodology, etc.). This consensus statement provides a list of recommendations about how bicycle set-up dimensions should be measured and the best practices for collecting cycling kinematic data. These recommendations should improve the transparency, reproducibility, standardisation and interpretation of bicycle measurements and cycling kinematic data for researchers, bicycle fitters and cycling related practitioners.