bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal and Early Postnatal Odorant Exposure Heightens Odor-Evoked Mitral Cell Responses in the Mouse Olfactory Bulb
Authors: Liu Annie , Urban Nathaniel N. 
Published: September 2017

AbstractEarly sensory experience shapes the anatomy and function of sensory circuits. In the mouse olfactory bulb (OB), prenatal and early postnatal odorant exposure through odorized food (food/odorant pairing) not only increases the volume of activated glomeruli but also increases the number of mitral and tufted cells (M/TCs) connected to activated glomeruli. Given the importance of M/TCs in OB output and in mediating lateral inhibitory networks, increasing the number of M/TCs connected to a single glomerulus may significantly change odorant representation by increasing the total output of that glomerulus and/or by increasing the strength of lateral inhibition mediated by cells connected to the affected glomerulus. Here, we seek to understand the functional impact of this long-term odorant exposure paradigm on the population activity of mitral cells (MCs). We use viral expression of GCaMP6s to examine odor-evoked responses of MCs following prenatal and early postnatal odorant exposure to two dissimilar odorants, methyl salicylate (MS) and hexanal, which are both strong activators of glomeruli on the dorsal OB surface. Previous work suggests that odor familiarity may decrease odor-evoked MC response in rodents. However, we find that early food-based odorant exposure significantly changes MC responses in an unexpected way, resulting in broad increases in the amplitude, number, and reliability of excitatory MC responses across the dorsal OB.
Spatial Structure of Synchronized Inhibition in the Olfactory Bulb
Authors: Arnson Hannah A. , Strowbridge Ben W. 
Published: September 2017

Olfactory sensory input is detected by receptor neurons in the nose, which then send information to the olfactory bulb (OB), the first brain region for processing olfactory information. Within the OB, many local circuit interneurons, including axonless granule cells, function to facilitate fine odor discrimination. How interneurons interact with principal cells to affect bulbar processing is not known, but the mechanism is likely to be different from that in sensory cortical regions because the OB lacks an obvious topographical organization. Neighboring glomerular columns, representing inputs from different receptor neuron subtypes, typically have different odor tuning. Determining the spatial scale over which interneurons such as granule cells can affect principal cells is a critical step toward understanding how the OB operates. We addressed this question by assaying inhibitory synchrony using intracellular recordings from pairs of principal cells with different intersomatic spacing. We found, in acute rat OB slices from both sexes, that inhibitory synchrony is evident in the spontaneous synaptic input in mitral cells (MCs) separated up to 220 μm (300 μm with elevated K+). At all intersomatic spacing assayed, inhibitory synchrony was dependent on Na+channels, suggesting that action potentials in granule cells function to coordinate GABA release at relatively distant dendrodendritic synapses formed throughout the dendritic arbor. Our results suggest that individual granule cells are able to influence relatively large groups of MCs and tufted cells belonging to clusters of at least 15 glomerular modules, providing a potential mechanism to integrate signals reflecting a wide variety of odorants.SIGNIFICANCE STATEMENTInhibitory circuits in the olfactory bulb (OB) play a major role in odor processing, especially during fine odor discrimination. However, how inhibitory networks enhance olfactory function, and over what spatial scale they operate, is not known. Interneurons are potentially able to function on both a highly localized, synapse-specific level and on a larger, spatial scale that encompasses many different glomerular channels. Although recent indirect evidence has suggested a relatively localized functional role for most inhibition in the OB, in the present study, we used paired intracellular recordings to demonstrate directly that inhibitory local circuits operate over large spatial scales by using fast action potentials to link GABA release at many different synaptic contacts formed with principal cells.
Optimum Age of Starter for Microbial Transglutaminase (MTGase) Production Produced by Streptomyces thioluteus TTA 02 SDS 14 and Characterization of Crude Enzyme
Authors: Zilda Dewi Seswita , Fawzya Yusro Nuri , Nur'amaliyah Lia Siti , Prestisia Hana Nurullita , Mubarik Nisa Rachmania , Lisdiyanti Puspita 
Published: September 2017

The condition of starter plays important role in enzyme production. Optimum starter will lead to the optimum yield of enzyme production. The experiments which were aimed to obtain the optimum age for starter of Streptomyces thioluteus TTA 02 SDS 14 from solid as well as liquid medium had been carried out which would be used for transglutaminase production. Medium used for culture maintenance, starter optimization and enzyme production was described by Bahrim. The result showed that S. thioluteus TTA 02 SDS 14 was ready to be used as starter after being cultured on solid medium continued in liquid medium each for 6 days. The enzyme production in a bioreactor using optimized starter produced enzyme with the highest activity after being fermented for 2 days with 150 rpm agitation. The crude enzyme active optimally at 45-50 oC, pH of 6 and no effect of metal ion and inhibitor on enzyme activity.
Criando uma consciência ambiental através de práticas sustentáveis na ONG casa da acolhida, no Município de Campina Grande – PB
Authors: Medeiros Mellyne Palmeira , Guimarães Williams Idelfonso , Almeida Amanda Martins 
Published: September 2017

<p>Relata a experiência obtida através do projeto de extensão “Conscientização ambiental e práticas sustentáveis” desenvolvido na ONG “Casa da Acolhida São Paulo da Cruz” teve como objetivo criar uma consciência sustentável nos internos dessa instituição, fazendo-os se preocuparem mais com o meio ambiente. A metodologia utilizada foi aulas teóricas e práticas sobre coleta seletiva, compostagem, cultivo de hortas e reutilização de água da chuva. Foram desenvolvidas compostagem, ambientalmente adequada, observando normas operacionais específicas. A execução desse projeto promoveu a criação de identidade sustentável através de atividades teóricas e práticas envolvendo a separação adequada de resíduos sólidos para diminuir o acumulo e facilitar a reutilização, o processo de compostagem para a fabricação de adubo a construção de uma mini horta e utilização de água da chuva para fins de serviços. Observou-se, portanto, que o despertar de uma consciência sustentável possibilitou o bem estar social na instituição hospedeira do projeto. </p>
Pengaruh Gaya Kepemimpinan dan Budaya Organisasi pada Kinerja Guru dengan Motivasi Sebagai Variabel Intervening
Authors: Dewanggi H.P. Aurelia , Sawitri Hunik Sri Runing 
Published: September 2017

<p><em>Purpose of this study to analyze the effects of leadership style, organizational culture on motivation and performance of senior high school techers in Wonogiri. Job performance is very necessary for any profession. Job performance of teacher increasingly organizational performance so that purpose of company or organization can be reachable. Many factors which can increase job/activity such as leadership style, organizational culture, and motivation.How far leadership style and organizational culture influence to job performance is tested in this research, by insert motivation as intervening variables.</em></p><p><em>Test utilized to analyze leadership style and organizational culture influence to job performance that is path analysis,R<sup>2</sup>test, as well as statistic T test, and direct and inderct effect. Research data obtained from questionary answer propagated to the teacher of senior high school in Wonogiri. Result of research analysis express that leadership style and organizational culture has positive influence and significant to teachers job performance. And Motivation proof to be intervening variabel in relationship beetwen leadership style and organizational culture to teachers job performance.</em></p>
Human Immunodeficiency Virus Infection and Hip and Knee Arthroplasty
Authors: Dimitriou Dimitrios , Ramokgopa Mmampapatla , Pietrzak Jurek R.T. , van der Jagt Dick , Mokete Lipalo 
Published: September 2017

Update
This article was updated on November 13, 2019, because of a previous error. On page 1, in the Results section of the Abstract, the sentence that had read “HIV-positive patients had a significantly elevated risk of periprosthetic joint infection, at 7.6%, compared with HIV-negative patients, at 3.3% (relative risk = 2.28, 95% confidence interval = 2.14 to 2.43)” now reads “HIV-positive patients had a significantly elevated risk of complications, at 7.6%, compared with HIV-negative patients, at 3.3% (relative risk = 2.28, 95% confidence interval = 2.14 to 2.43).”
An erratum has been published: JBJS Reviews. 2019 Nov;7(11):e7.

Background:
Modern management of human immunodeficiency virus (HIV) infection has afforded patients longevity while increasing the burden of arthroplasty procedures because of the increased risk of osteonecrosis, fragility fractures, and degenerative joint disease. Early publications on hip and knee arthroplasty in HIV-positive patients reported a high risk of complications, although some more recent publications demonstrated acceptable outcomes. Despite the widespread nature of the HIV pandemic, there is a paucity of literature addressing outcomes following joint arthroplasty in infected patients. We pooled available studies to obtain the best evidence regarding the safety of total hip and knee arthroplasty procedures in HIV-positive patients. The studies identified were heterogeneous, precluding a meta-analysis. However, we performed a review of the literature focusing on complications and outcomes.

Methods:
Twenty-one published English-language articles involving 6,516,186 joints were identified by a systematic review as suitable for inclusion in the study. The articles were analyzed for complication and prosthesis survivorship rates and relative risks.

Results:
An overall complication rate of 3.3% was found across the 19 articles that provided such data. HIV-positive patients had a significantly elevated risk of complications, at 7.6%, compared with HIV-negative patients, at 3.3% (relative risk = 2.28, 95% confidence interval = 2.14 to 2.43). Eleven articles were suitable for analysis of prosthesis survivorship, and survivorship rates did not differ significantly between HIV-positive and negative patients.

Conclusions:
Total hip and total knee arthroplasty appear to be safe procedures with acceptable outcomes in HIV-positive patients.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Interaksi Good Corporate Governance, Corporate Social Responsibility, Intellectual Capital Dan Pengaruhnya Terhadap Kinerja Keuangan Perusahaan
Authors: Rosafitri Citra 
Published: September 2017

This study aims to determine effect of Good corporate governance, corporate social respinsibility dan intellectual capitalon the financial performance proxied Return on Asset and Return on Equity of companies listed on the Indonesian Stock Exchange.
This research method used in this study is a quantitative method to test the assumption of calssical analysis techniques and double linear regresion testing. A sample size of 64 is comprised of 16 companies that meet the criteria specified through purposive sampling.
The result of this studi indicate that Good corporate governance consist of institusional ownership, managerial ownership and independent director has no effect on financial performance proxied by Return on Asset and Return on Equity. Corporate social responsibility has effect the Return on Asset and Return on Equity. An than the Intellectual capital consist of VA has effect the Return on asset, and VACA,VAHU, STVA has no effect of Return on Asset, the second proxcied financial performance of Intellectual capital has no effect to Return on Equity. And as well as Good Corporate governance, Corporae Social Responsibility and intellectual capital simultaneously do effect the Financial performace proxied by Return on Asset an Return on Equity.
The switch to refillable bottled water in Indonesia: a serious health risk
Authors: Komarulzaman Ahmad , de Jong Eelke , Smits Jeroen 
Published: September 2017

Abstract
In recent years, the consumption of refillable bottled water has increased considerably in emerging countries. However, the quality of this water is often questionable, as authorities lack the capacity to properly check refilling depots. Given that refillable bottled water not only replaces unimproved water sources, but also better-quality sources, like piped and branded bottled water, its increasing use poses a major health risk. We investigate the motives behind the decision to switch to refillable bottled water in Indonesia. Findings indicate that this switch is driven by lifestyle motives, as well as by cost and availability considerations. It is mostly the young affluent households who switch from piped and ‘other’ sources to refillable bottled water. In rural areas, the tendency to make this switch is negatively affected by availability problems and the higher price of refillable bottled water. Availability and cost also influence the switch from branded bottled to refillable bottled water, but here it is the poorer households who have a higher propensity to switch. Further exploration of the lifestyle motive and affordability issues, as well as better monitoring of the refilling depots, are needed to improve the quality of drinking water in Indonesia and other emerging countries.
Ruptured Bronchial Artery Aneurysm Treated With Aortic Stent Graft and Aneurysm Embolization
Authors: Xu Zhiwei , Kong Ye , Hu Chuanxian , Huang Su , Tan Yan 
Published: September 2017

Background:
Mediastinal bronchial artery aneurysms are uncommon, with fewer than
40 published case reports. This study objective was to evaluate the short term follow up of two
cases ruptured Bronchial Artery Aneurysm (rBAA) treated with aneurysm embolization and subsequent
aortic stent graft.

Methods:
Two cases of rBAA were treated with a combination of an aortic stent-graft and aneurysm
embolization. With rBAA, aneurysm embolization could be performed with sodium polymannuronate
until the aneurysm was almost completely packed. One of the limitations of aneurysm
embolization is spontaneous recanalization of previously occluded aneurysm. So a stent-graft was
deployed to isolate the feeding artery of the rBAA from the descending aorta. The 3 months follow-
up after the procedure included chest or back pain and computed tomographic angiography.

Results:
The hospital stays of the 2 cases were 5 and 7 days. Chest or back pain was disappeared.
There were no hospital deaths and late deaths. Computed tomographic angiogram showed no recanalization
and no hemothorax. These 2 patients have not reported any complications up to now.

Conclusion:
Aortic stent graft combined with aneurysm embolization is a minimally invasive, effective
and safe method for rBAA.
The Molecular Study of Antibiotic Resistance to Quinolones in Salmonella enterica Strains Isolated in Tehran, Iran
Authors: Malehmir Shirin , Ranjbar Reza , Harzandi Naser 
Published: September 2017

Introduction:Salmonellais known as one of the most important causes of gastrointestinal disease in the world. Quinolones and fluoroquinolones are used successfully in the treatment of salmonellosis particularly for infections that have become resistant to several antibiotics. But non-susceptible isolates to quinolones have been reported in several countries. The data are limited about the prevalence of quinolone-resistant isolates in our country. Therefore, this study investigated the plasmid-mediated quinolone resistance genes inSalmonella entericaisolated in Children's Medical Center in Tehran during 2014-2015.Methods and Materials:Salmonellaisolates were isolated and identified using standard microbiological methods. Antibiotic susceptibility testing and screening ofSalmonellastrains resistant to quinolones were performed according to the CLSI guidelines. The molecular investigation was done using specific primers for detection of qnr genes including:qnrA,qnrB andqnrS, by polymerase chain reaction.Results:Overall, 92 (66.6%) strains were resistant to nalidixic acid. None of the strains showed resistance to ciprofloxacin. Out of the 92 nalidixic acid resistant strains, 52 (56.52%) harboredqnrS genes, 15 strains (16.30%) had bothqnrA andqnrS genes. Two (1.1%) isolates were positive forqnrB gene. Twenty four (26.08%) nalidixic acid resistant isolates did not have any qnr qens.Conclusion:The results of this study show high prevalence of resistance to nalidixic and qnr genes inSalmonellaisolates. Plasmid nature of this type of resistance poses an increased risk of dissemination of quinolone resistance betweenSalmonellaand non-Salmonellaisolates circulating in hospitals environments.
Prevalence of Patients Receiving Publicly Funded Renal Replacement Therapy in Brazil: Regional Inequities and Costs
Authors: Soares dos Santos Junior Augusto Cesar , Junior Fernando das Mercês Lucas , Farah Kátia de Paula , do Nascimento Ana Carolina Aguiar , Nogueira José Luiz Santos , Amaral Carlos Faria Santos , Kelles Silvana Marcia Bruschi 
Published: September 2017

Introduction:
In recent years, the number of patients with end-stage renal disease has rapidly increased worldwide. In Brazil, recent surveys have undisclosed a trend towards an increase in the prevalence of this condition.

Aims and Objectives:
This study aimed at describing the prevalence of patients with end-stage renal disease (ESRD) receiving publicly funded dialysis in Brazil.

Methods asnd Materials:
Data concerning the prevalence and mortality of patients with ESRD being provided renal replacement therapy by the SUS from 2008 to 2013 were collected at the DATASUS databank (www2.datasus.gov.br), the Authorization System for High Complexity/Cost Procedures (APAC) database, the SUS Ambulatory Information System (SIA) and the Mortality Information System (SIM) database.

Results:
From 2008 to 2013 there was a 25% increase in the absolute number of hemodialysis sessions (10,022,962; 12,561,623). This resulted in an estimated overall increase of 18% in the ratio of patients on hemodialysis per million population (352 pmp; 416 pmp). There were considerable differences among Brazilian States regarding the prevalence of patients with ESRD on hemodialysis. In 2013, the prevalence ranged from 173 pmp (State of Amazonas) to 531 pmp (State of Minas Gerais). The leading Brazilian States, in absolute number of patients, were São Paulo (19,301), Minas Gerais (10,940) and Rio de Janeiro (8,510), all of them in the southeast region. In 2013, the overall mean mortality rate was 18.4%. From 2008 to 2013, the renal transplantation rate increased from 35.2 to 41.6 transplants per year per million inhabitants. In 2013, hemodialysis was the most frequent modality of therapy, corresponding to 87.1% of the cases, followed by CAPD (9.2%) and APD (3.7%).

Conclusion:
In Brazil, chronic kidney disease is steadily increasing in prevalence and rapidly becoming a major public health concern. Therefore, policies towards prevention and strategies to avoid underdiagnose and assure broad access to renal replacement therapy should be strengthened nationwide.
Accuracy of an Automatic Infusion Controller (AutoClamp) for Intravenous
Fluid Administration
Authors: Choi Geun Joo , Yoon Il Jae , Lee Oh Haeng , Kang Hyun 
Published: September 2017

Background:
This study was purposed to compare in vitro the volumetric accuracy of a newly introduced
automatic infusion controller, AutoClamp with that of other commonly used infusion devices.

Methods:
Four different
volumetric infusion devices were used to examine the accuracy: Terufusion TE-112; Volumed µVP7000; AutoClamp; and
Infucon. Accuracy was determined for each flow rate (20, 40, 100, and 200 ml/h) by using infusate volumes collected after
3 h of initiating the fluid administration. Accuracy was calculated as the percentage difference between set volume and
actual volume delivered. The influences of fluid viscosity and flow resistance on infusion device accuracy were also
evaluated.

Results:
There were no cases of a greater-than-10% difference between set volume and actual delivered volume.
The accuracy of the Infucon was significantly less than that of the other devices. Infusion devices proved to be consistent
and unaffected by fluid viscosity or flow resistance except for the Infucon.

Conclusion:
The accuracy of the
AutoClamp was comparable to that of other commonly used infusion pumps (Terufusion TE-112 and Volumed µVP7000)
regardless of infusate viscosity and flow resistance.
Analysis of Productivity Plankton and Trophic Status Beratan Lake Ecosystem Tabanan Regency, Bali Province
Authors: Suryani Sang Ayu Made Putri , Arya I Wayan 
Published: September 2017

Beratan Lake is used for fish cultivation activity, tourism, agriculture, and disposal activity. Utilization level is too high and makes lake ecosystem disturbed especially phytoplankton. Phytoplankton existence in water is acting as primary production and act to determine water quality on physical or chemical. The purpose of this research is to know plankton productivity and trophic status ecosystem Beratan Lake. Beratan Lake utilization that too high will impact in ecological pressure at lake ecosystem like decreasing water productivity and quality. The result of the research can conclude that water premier productivity of Beratan Lake is too low especially in cultivation fish territory that has phytoplankton abundance is 4585 individuals per ml that make Beratan Lake is classified to a lake that its trophic status is oligotrophic. The variety of phytoplankton and zooplankton that found in Beratan Lake shows low variety where it only found 5 classes and 11 species of phytoplankton and also 2 classes dan 3 species of zooplankton.
Diversidad de las subfamilias Grewioideae y Tilioideae (Malvaceae) en Guerrero, México
Authors: Gual Díaz Martha , Diego Pérez Nelly 
Published: September 2017

Antecedentes y Objetivos: En México las subfamilias Brownlowioideae, Grewioideae y Tilioideae (Malvaceae) están representadas por 11 géneros, 75 especies y una variedad; de estos taxones, 44 especies y la variedad son endémicas de su territorio. La distribución total abarca 28 estados, destaca la mayor diversidad de especies en las zonas tropicales de dos estados del centro-sureste del país (los tres primero lugares corresponden a Oaxaca, Chiapas y Guerrero). El objetivo de este trabajo fue caracterizar a las especies presentes en el estado de Guerrero, aportando información detallada acerca de la diversidad, distribución y endemismo, conocimiento que nos lleva a comprender mejor a un grupo de plantas poco estudiadas en el país.Métodos: Se analizó la información contenida en estudios regionales de florística, taxonomía y vegetación, de los especímenes colectados en la entidad, depositados en herbarios y disponibles en internet, y se colectó material en campo. Con lo anterior, se elaboró el listado final; se realizaron las descripciones correspondientes a los géneros y especies, y se prepararon las claves para la determinación de éstos.Resultados clave: Los géneros con mayor número de especies son Triumfetta (19) y Corchorus (5). Se proporcionan claves dicotómicas para la identificación de los géneros y las especies registrados en el estado, su descripción, sinonimia, cita de su publicación, datos ecológicos e información de los especímenes de respaldo, así como de sus usos. Se incluyen mapas de distribución geográfica en el estado y una ilustración por cada género.Conclusiones: Se presenta la revisión florística-taxonómica de siete géneros y 32 especies de las subfamilias Grewioideae y Tilioideae (Malvaceae) registradas en Guerrero.