bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dupuytren’s disease and occupational mechanical exposures: a systematic review and meta-analysis
Authors: Jahn Alexander , Andersen Johan Hviid , Descatha Alexis , Dalbøge Annett 
Published: September 2024

The risk of developing Dupuytren’s disease among workers exposed to occupational mechanical exposures has been reported in few systematic reviews, mainly related to vibration. Expanding the investigation to all occupational mechanical exposures is essential for advancing scientific knowledge, health policies and improving workplace safety. The aim of this systematic review and meta-analysis was to study the association between occupational mechanical exposures and Dupuytren’s disease.We conducted a systematic review and meta-analysis using guidelines stated by PRISMA. The systematic literature search was performed in Medline, EMBASE, CINAHL, Cochrane Library and Web of Science databases in April 2023. Inclusion criteria were conducted using the PECOS. Two independent authors conducted the literature screening, data extraction and risk of bias assessment. In the meta-analyses, data was pooled using random-effects models and stratified by the risk of bias and study design. The level of evidence was evaluated using GRADE.The literature search identified 563 unique articles and 15 were deemed eligible for inclusion, categorised into hand-transmitted vibration, lifting/carrying loads and combined mechanical exposures. Exposure to hand-transmitted vibration showed an OR of 2.0 (95% CI 1.5 to 2.7, I2=64%), lifting/carrying loads had an OR of 1.5 (95% CI 1.1 to 2.0, I2=77%) and combined mechanical exposures had an OR of 2.1 (95% CI 1.4 to 3.1, I2=94%). When grading the level of evidence, we found moderate evidence for hand-transmitted vibration, while low evidence was found for lifting/carrying loads and combined mechanical exposures.We found an association between hand-transmitted vibration, lifting/carrying loads and combined mechanical exposures. The level of evidence was considered moderate for hand-transmitted vibration and low for lifting/carrying loads and combined mechanical exposures.
Genes deregulated in giant cell arteritis by Nanostring nCounter gene expression profiling in temporal artery biopsies
Authors: Ferrigno Ilaria , Bonacini Martina , Rossi Alessandro , Nicastro Maria , Muratore Francesco , Boiardi Luigi , Cavazza Alberto , Bisagni Alessandra , Cimino Luca , Ghidini Angelo , Malchiodi Giuseppe , Zerbini Alessandro , Pipitone Nicolò , Salvarani Carlo , Croci Stefania 
Published: September 2024

ObjectiveTo identify differentially expressed genes in temporal artery biopsies (TABs) from patients with giant cell arteritis (GCA) with different histological patterns of inflammation: transmural inflammation (TMI) and inflammation limited to adventitia (ILA), compared with normal TABs from patients without GCA.MethodsExpression of 770 immune-related genes was profiled with the NanoString nCounter PanCancer Immune Profiling Panel on formalin-fixed paraffin-embedded TABs from 42 GCA patients with TMI, 7 GCA patients with ILA and 7 non-GCA controls.ResultsUnsupervised clustering of the samples revealed two distinct groups: normal TABs and TABs with ILA in one group, 41/42 TABs with TMI in the other one. TABs with TMI showed 31 downregulated and 256 upregulated genes compared with normal TABs; they displayed 26 downregulated and 187 upregulated genes compared with TABs with ILA (>2.0 fold changes and adjusted p values <0.05). Gene expression in TABs with ILA resembled normal TABs although 38 genes exhibited >2.0 fold changes, but these changes lost statistical significance after Benjamini-Yekutieli correction. Genes encoding TNF superfamily members, immune checkpoints, chemokine and chemokine receptors, toll-like receptors, complement molecules, Fc receptors for IgG antibodies, signalling lymphocytic activation molecules, JAK3, STAT1 and STAT4 resulted upregulated in TMI.ConclusionsTABs with TMI had a distinct transcriptome compared with normal TABs and TABs with ILA. The few genes potentially deregulated in ILA were also deregulated in TMI. Gene profiling allowed to deepen the knowledge of GCA pathogenesis.
Advancing Global Health Equity in Oncology Clinical Trial Access
Authors:   Bloomberg New Economy International Cancer Coalition, Adewole Tolulope , Albrecht Bjorn , Beg Shaalan , Brawley Otis , Chang I-Fen , Daly Bobby , de Claro Angelo , Dent Jennifer , Dickler Maura , Ene-Obong Abasi , Fashoyin-Aje Lola , Finnegan Justin , Galbraith Susan , Gospodarowicz Mary , Gralow Julie , Haddad Tufia , Kalidas Chitkala , Katz Artur , Kaucic Karen , Keane Harriet , Lanasa Mark , Legos Jeff , Li Bob T. , Mills Jennifer , Oelrich Stefan , Olopade Stefan , Palma John , Pazdur Richard , Pilarski Piotr , Qian Jing , Rudd Kevin , Shokrpour Sepideh , Tendler Craig , Wilson Matt , Smart Victoria W. , Wu Yi-Long , Yan James , Zhang Lianshan ,   McKinsey Cancer Center, Li Diya , Shen Johanna , Silverstein Amy ,   Cure4Cancer, Abou-Alfa Ghassan , Anderson Shelly , Beyrer Patrick , Carnival Danielle , Clarke Stephen , Conneran Terri , DeAngelis Lisa M. , Diakos Connie , Diaz Luis , dos Anjos Carlos Henrique , Drebin Jeffrey A. , Eisenmen Debra , Flannery Russell , Fredrickson David , Isbell James M. , Jones David R. , Joseph Adedayo , Kennedy Caroline , Kingham T. Peter , Lee Adrian , Lee Nancy Y. , Leigh Lillian , Li Zhi-Zhong , Liu An-Wen , Liu Dazhi , Liu Si-Yang , Maggie Liu Si-Yang , Makker Vicky , Mallafre-Larrosa Meritxell , McBride Sean , Mestres Isabel , Mondaca Sebastian , Nigro Paulo , Norton Larry , Oyler John V. , Pavlakis Nick , Powell Simon , Robinson Bruce , Qin Yi , Razavi Pedram , Reis-Filho Jorge , Rocco Gaetano , Rudin Charles M. , Schell Orville , Scher Howard I. , Schrag Deborah , Simon Greg , Smith Dorrance , Speece Morgan , Tu Hai-Yan , Umar-Sadiq Aminu , Wang Bu-Hai , Wheeler Helen , Xu Chong-Rui , Yan Li-Xu , Yang Fan , Yoon Byeong , Young Catharine , Zhang Jia-Tao , Zhou Qing 
Published: September 2024

Summary:
Despite exponentially increased industry investment in oncology research and development with more than $80 billion spent annually, patient enrollment in clinical trials remains below 5% globally. Our multistakeholder international cancer coalition envisions ecosystem transformation with capacity building through a global “hub-and-spoke” network model to expand access to and accelerate clinical trials, thus ending cancer as a major cause of death in this lifetime.
Cigarette Smoking and Observed Growth of Unruptured Intracranial Aneurysms: A Systematic Literature Review and Meta-Analysis
Authors: Pachón-Londoño Maria José , Ghoche Maged T. , Nguyen Brandon A. , Maroufi Seyed Farzad , Olson Vita , Patra Devi P. , Turcotte Evelyn L. , Wang Zhen , Halpin Brooke S. , Krishna Chandan , Turkmani Ali , Meyer Fredric B. , Bendok Bernard R. 
Published: September 2024

BACKGROUND:
Smoking and observed growth of intracranial aneurysms are known risk factors for rupture. The mechanism by which smoking increases this risk is not completely elucidated. Furthermore, an association between smoking and aneurysm growth has not been clearly defined in the literature. We hypothesize that smoking is associated with aneurysm growth, which, in turn, may serve as one of the mechanisms by which smoking drives rupture risk.

METHODS:
We report a systematic review of the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines. Using the R software, we performed a meta-analysis to investigate the association between smoking and the growth of unruptured intracranial aneurysms. Studies on familial aneurysms and genetic syndromes known to increase the risk of aneurysms were excluded.

RESULTS:
Eighteen observational studies were included with a total of 3535 patients and 4289 aneurysms with a mean follow-up period ranging from 17 to 226 months. The mean age among the studies ranged from 38.4 to 73.9 years; 74% of patients were female. Ever-smoking status (odds ratio, 1.10 [95% CI, 0.87–1.38]) and current smoking status (odds ratio, 1.43 [95% CI, 0.84–2.43]) did not show a statistically significant association with growth of intracranial aneurysms. Patients currently smoking did not have a statistically significant association with the growth of intracranial aneurysms (odds ratio, 1.18 [95% CI, 0.72–1.93]) compared with patients without a smoking history. No significant association was found in patients who previously smoked compared with patients who never smoked (odds ratio, 1.46 [95% CI, 0.88–2.43]).

CONCLUSIONS:
Smoking is not clearly associated with the growth of unruptured intracranial aneurysms, despite trends being observed, there is no statistical association. The mechanism by which smoking increases rupture risk might not be growth. In patients for whom observation is recommended, the absence of growth over time in the setting of smoking history does not, therefore, imply protection from rupture.
Generative and Adversarial: Art and the Prospects of AI
Authors: Kuo Michelle , Lee Pamela M. 
Published: September 2024

Abstract
This essay serves as an introduction to the Questionnaire on Art and Machine Learning. It opens with the testimony of Sam Altman before the US Senate Judiciary Committee on Privacy, Technology and the Law in May 2023, following the launch of ChatGPT a year earlier. ChatGPT is part of a wave of generative AI: AI that not only classifies or analyzes information but also generates it. Media responses to ChatGPT and a range of other text-to-image and text-to-video generators—including Dall-E, Stable Diffusion, MidJourney, Deep AI, and Sora—tend to divide between “Boosterism” and “Doomerism”: They either echo Silicon Valley's habitual refrain about the inherent goodness of technological innovation or they describe dystopian scenarios in which human agency is all but eclipsed. “Generative and Adversarial: Art and the Prospects of AI” argues that artists, art historians, critics, and curators offer far more nuanced perspectives on the prospects of AI. Borrowing the language of “generative adversarial networks”—one of several machine-learning models that have revolutionized image production in the past decade—it interrogates AI's aesthetic, political, and ethical possibilities, as well as its historical genealogies.
Bataille and Eisenstein: In Defense of Michelson's View
Authors: Turvey Malcolm 
Published: September 2024

Abstract
In October 188's “Visceral Economies, Queer Dialectics: Eisenstein Meets Bataille,” Elena Vogman argues that there is an “affinity” between Sergei Eisenstein's and Georges Bataille's views, thereby contesting Annette Michelson's verdict that any similarities between them are “superficial.” This article contends that Michelson is right, and that Vogman provides no evidence of an affinity between Eisenstein's and Bataille's thinking. In doing so, I defend the important methodological principle, exemplified by Michelson's work, that theory should not be applied, top down and a priori, to art as if it were mere grist for the theory mill. Eisenstein was a deeply original thinker and filmmaker, and while he might have shared some of Bataille's interests, he did so for reasons antithetical to Bataille's. His work should not, therefore, be appropriated by what Michelson called the “veritable Bataille industry … [that] has proliferated to the point of generating a grille through which the reading of the Eisensteinian text is now proposed.”
The Last Sculptures (For Richard Serra)
Authors: Dickerman Leah 
Published: September 2024

Abstract
In 2022, Richard Serra installed a massive forged steel column that stood centered and alone in the gallery and whose surface was gouged in a way that resembled bite marks or scars. The gallerist David Zwirner conveyed that the artist had said that this sculpture was his last. Hal Foster's volume of long form interviews with Serra, Conversations about Sculpture (Yale, 2018) serves as a key source as the author explores: What does it mean to bring a career to a close? And what is the relationship between sculpture and death? The essay defines the features of Serra's late style, which played out in a series of forged sculptures ranging from Grief and Reason (for Walter) (2013) to the artist's last work, 2022. These works encompass as set of mnemonic gestures—invocations of the past—that include homages to people of formative intellectual or personal significance; reference to or reengagement with works, propositions, or modes of making from earlier in the artist's career; and the primordial forms and functions of sculpture itself. And in both their literal and affective weight, they invite thoughts of mortality.
The Kabbalistic Sefirot: Terminological and Structural Anticipations in Early Jewish and Christian Literature
Authors: Zinner Samuel 
Published: September 2024

Abstract
Lists of personified virtues in ancient Jewish and Christian texts offer remote intellectual anticipations of names and structural configurations of later kabbalistic sefirot. These parallels indicate that various Jewish-oriented Christian sources preserved and mediated some traditions that later came to circulate in Jewish kabbalistic circles.
The Development and Administration of the London Convention and Protocol: ‘Two Instruments, One Family’ and Their Link to the United Nations Convention on the Law of the Sea
Authors: Birchenough Andrew , Haag Fredrik , Sun Zhen 
Published: September 2024

Abstract
The London Convention and London Protocol are the two main international treaties of global application addressing the protection of the marine environment from pollution caused by the dumping of wastes and other matter into the sea. This article describes how the treaties were developed and adopted, explores their relationship with the overarching 1982 United Nations Convention on the Law of the Sea (LOSC) and examines how the treaties are administered to implement their vision of ‘two instruments, one family’. The article also highlights the ground-breaking steps the London Convention and London Protocol have taken to address new threats to the ocean, which include regulating new climate change mitigation technologies that have the potential to cause harm to the marine environment.
Trading places with the traitor: Pieter Pourbus (c. 1523-1584) and sixteenth-century Last Supper iconography
Authors: de Klerck Bram 
Published: September 2024

Pieter Pourbus’ Last Supper of 1548 (Bruges, Groeningemuseum) contains some unusual iconographic elements that have not yet been extensively analysed: the figure of Judas, rising from the table and making a move to leave the gathering; the devilish creature entering the room from the right; the boy picking up the overturned chair in the foreground. By making use of recent scholarly insights into the employment of the anthropological concept of ‘liminality’ in the context of the visual arts (notably by Lynn Jacobs on Early and Renaissance Netherlandish painting and manuscript illumination), this contribution aims to show that these features were meant to enhance the contemporary viewer’s involvement in the depiction. The work seems to invite them to enter, as it were, the painted realm and to take Judas’ abandoned place.
An investigation of Last Supper imagery in the Western European visual arts from the late Middle Ages and the Renaissance reveals that in some cases the figure of Judas plays a distinctive role in the presentation of the iconography and in the viewer’s devotional and psychological experience of participation in the sacred story. Sometimes, as in a panel from the circle of the Master of the Amsterdam Death of the Virgin (c. 1485-1500) or in the likewise anonymous Antwerp Last Supper (c. 1525-1530), a mortal human has been included in the painting, portrayed in the immediate vicinity of the scene and apparently being ready and prepared to take over Judas’ place once the latter leaves the gathering.
Pieter Pourbus’ painting, which probably played a role in the literary-religious context of the Bruges rederijkers’ Chamber of the Holy Spirit, is more inventive in nature. Lacking an intermediary worshipper depicted in the foreground, it transfers this worshipper’s role to the viewer, thus establishing a bridge between the painted realm and the real world.
Busybodies and Quietists, Yesterday and Today: Discovering Debates about Phronēsis in Nicomachean Ethics 6.8
Authors: Tarantino Giancarlo 
Published: September 2024

Abstract
Nicomachean Ethics 6.8 has been interpreted in a variety of ways. One dispute involves Aristotle’s remarks about the relationship of phronēsis to politics: does Aristotle claim that phronēsis is foremost applicable to an individual’s private life, to the political realm, or to some combination of the two? Two features of this dispute make it worthy of closer attention. First, the conflict of interpretations has not been documented as such. Second, I argue this contemporary conflict is a repetition of an ancient conflict about phronēsis that was being waged in 5th/4th century Athens. Phronēsis was a contested term alongside two related terms, apragmosynē (quietism) and polypragmosynē (meddlesomeness), and the construction of lines 1141b23–1142a12 enters into this historical debate to create a productive tension between two rival views. Aristotle heightens the tension between views represented by quietists and busybodies for his own purposes. In section 1, I surface the neglected historical frame of Nicomachean Ethics 6.8. In section 2, I turn to the contemporary conflict of interpretations, showing how it repeats the historical frame in many ways, and I provide a basic taxonomy of the views typically offered. In section 3, I bring the two debates – historical and contemporary – together and offer my own view of what Aristotle is up to in the passage. I argue that centering the historical frame in this passage highlights Aristotle’s use of Isocratean-style phronēsis, while also transforming the concept by connecting it to a series of questions that go beyond Isocrates’ view, thus preparing for a later exploration of the best forms of human living.
Articulation of Sufi Path and Doctrines in the Poetry of Khwāja Muḥammad Zamān Naqshbandī of Luārī
Authors: Anjum Tanvir 
Published: September 2024

Abstract
Khwāja Muḥammad Zamān Luārvī (i.e., of Luārī or Lowārī) was a much-revered eighteenth-century Sufi shaykh (master) who spent his entire life in Luārī and Thatta in lower Sindh. Spiritually affiliated with the Naqshbandī Silsilah, he was also an eloquent Sufi poet. Though small in volume, his poetic compositions are highly symbolic and replete with complex Sufi philosophical and cosmological themes. This article identifies and analyzes the Sufi doctrines in his poetry by undertaking a poetic exegesis of his verses within a Sufi framework. It briefly introduces the life and poetry of the Khwāja, analyzes the articulation of Sufi doctrines in his poetic verses, and assesses his poetry’s characteristics.
Soft yet secure: Exploring membrane buckling for achieving a versatile grasp with a rotation-driven squeezing gripper
Authors: Nguyen Khoi Thanh , Nguyen Nhan Huu , Ho Van Anh 
Published: September 2024

Nowadays, there is a growing demand for versatile robotic grippers that facilitate adaptive grasping across a range of objects, characterized by diverse attributes such as shapes, sizes, and mechanical properties. This research introduces a new soft gripper, denoted as ROSE (ROtation-based Squeezing GrippEr), dedicated to the torsional buckling phenomenon to achieve its grasping capability. The inherent gripping pattern, formed through a single rotational actuation, enables ROSE to dynamically accommodate various objects (relatively smaller than the diameter of ROSE), even in challenging environments like an oil container, without a complicated controller. Experimental tests demonstrate that ROSE exhibits substantial gripping force, reaching up to more than 300 N in the specific setup, and a remarkable payload-to-weight ratio. Especially, ROSE can maintain mechanical integrity through long-term open-close operation cycles in a specific condition. In this paper, we also introduce non-linear simulations for the elaboration of behaviors of ROSE concerning different morphologies, encompassing geometry configurations and material properties. The findings highlight a significant correlation between morphological features and grasping performance, leading to the refinement of a dependable version of ROSE. This refined version was subsequently assessed through experimental trials in crop harvesting tasks, where ROSE demonstrated high success rates in picking both individual and clustered crops, regardless of their soft or stiff characteristics. Project’s website with videos: https://sites.google.com/view/rosesoftgripper .
Non-Invasive Evaluation of Right Gastroepiploic Artery with Colour Doppler Echography
Authors: Agrifoglio M. , Di Matteo S. , Parolari A. , Naliato M. , Antona C. , Alamanni F. , Biglioli P. 
Published: September 2024

The right gastroepiploic artery has been increasingly used as a coronary bypass graft. Short- and mid-term patency rates support the supposition that the right gastroepiploic artery is a satisfactory bypass conduit. However, conclusive angiographic data on long-term patency rates are still lacking An echo-colour Doppler method was used to detect patency of the right gastroepiploic artery grafts through an upper abdominal approach. A group of 24 patients with a right gastroepiploic artery graft to the right or posterior descending coronary artery, all of whom also had a postoperative angiographic study which showed 100% patency of the graft were used as a reference group. A second group of 89 patients was also investigated only with echo-colour Doppler during the postoperative period (mean 8.0 (range 1–48) months). A patent right gastroepiploic artery graft showed a biphasic velocity pattern. Systolic peak velocity ranged from 8 to 26 cm and diastolic peak velocity from 4 to 13 cm. The right gastroepiploic artery diameter ranged from 1.7 to 2.4 mm and flow from 10.2 to 58.8 ml. Among the second group were three patients who had, at their echo-colour Doppler examination, a possible occlusion of the right gastroepiploic artery graft; an angiographic study was conducted and the graft closure confirmed in all cases Serial echo-colour Doppler evaluation of the right gastroepiploic artery blood flow pattern and diameter is a non-invasive and safe method to check the patency and flow capacity of the artery graft in follow-up studies.