bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unifying the Micro and Macro Properties of AGN Feeding and Feedback
Authors: Gaspari Massimo , Sądowski Aleksander 
Published: March 2017

Abstract
We unify the feeding and feedback of supermassive black holes with the global properties of galaxies, groups, and clusters by linking for the first time the physical mechanical efficiency at the horizon and megaparsec scale. The macro hot halo is tightly constrained by the absence of overheating and overcooling as probed by X-ray data and hydrodynamic simulations (

). The micro flow is shaped by general-relativistic effects tracked by state-of-the-art GR-RMHD simulations (

). The supermassive black hole properties are tied to the X-ray halo temperature

, or related cosmic scaling relation (as

). The model is minimally based on first principles, such as conservation of energy and mass recycling. The inflow occurs via chaotic cold accretion (CCA), the rain of cold clouds condensing out of the quenched cooling flow and then recurrently funneled via inelastic collisions. Within 100s gravitational radii, the accretion energy is transformed into ultrafast 104 km s−1 outflows (UFOs) ejecting most of the inflowing mass. At larger radii, the energy-driven outflow entrains progressively more mass: at roughly kiloparsec scale, the velocities of the hot/warm/cold outflows are a few 103, 1000, and 500 km s−1, with median mass rates ∼ 10, 100, and several 100

yr−1, respectively. The unified CCA model is consistent with the observations of nuclear UFOs and ionized, neutral, and molecular macro outflows. We provide step-by-step implementation for subgrid simulations, (semi)analytic works, or observational interpretations that require self-regulated AGN feedback at coarse scales, avoiding the a-posteriori fine-tuning of efficiencies.
Le Tesbih et l’iPhone : islam politique et libéralisme en Turquie
Authors: Robert Max-Valentin 
Published: March 2017

Jusqu’à la fin des années 1990, le discours économique porté par l’islam politique turc se caractérisait par son antilibéralisme. En acceptant l’économie de marché et en se faisant le porte-parole des « tigres anatoliens », l’AKP a donc incarné une rupture idéologique avec ses prédécesseurs islamistes. Toutefois, l’hétérogénéité de sa base électorale oblige ce parti à maintenir une ambivalence discursive sur l’UE et la globalisation.
L’Office of Net Assessment : plongée au cœur du think tank du Pentagone
Authors: Boutherin Grégory 
Published: March 2017

La prospective de défense américaine s’est développée depuis plus de quarante ans autour d’une structure originale : l’Office of Net Assessment (ONA). Ce bureau, dirigé jusqu’en 2015 par Andrew Marshall, n’a compté depuis sa création qu’une centaine de collaborateurs directs. Il a toutefois contribué à alimenter tout un écosystème de recherche stratégique. Ses analyses, fondées sur la méthode pluridisciplinaire du Net Assessment, ont eu un impact important, parfois bien au-delà des États-Unis.
L’équivalent patrimonial des droits à la retraite en France
Authors: Daniel Christophe , Nze Obame Jesus Herell , Séjourné Bruno , Lavigne Anne , Tagne Christian , Mottet Stéphane 
Published: March 2017

L’objectif de cet article est de développer une mesure de l’équivalent patrimonial des droits à retraite des assurés à la retraite avec les données de l’Échantillon Inter-régime de Retraités (EIR) de 2008. Contrairement aux données des enquêtes Patrimoine, les EIR fournissent une information exhaustive sur les conditions de liquidation des droits acquis par les assurés affiliés à l’ensemble des régimes de retraite et exposés aux réformes des retraites. Au niveau agrégé, avec un taux d’actualisation à 2 %, le montant total des engagements envers l’ensemble des retraités de tous les régimes de retraite s’élève à 4 765 milliards d’euros, soit 23,5 années de prestations de droits directs versées en 2008. Au niveau microéconomique, l’ampleur des engagements envers les assurés à la retraite varie d’un régime à l’autre et dépend de l’âge de liquidation, du sexe, et des conditions de liquidation qui, jusqu’en 2008, sont différentes entre les régimes des salariés du privé et ceux de la fonction publique.
Intelligence artificielle : une mine d’or pour les entreprises
Authors: Charlin Laurent 
Published: March 2017

Les innovations rendues possibles grâce aux récents progrès de l’intelligence artificielle sont vastes et pourraient avoir des répercussions sociales et industrielles majeures. Qu’est-ce qui distingue les techniques de l’intelligence artificielle moderne ? Comment les entreprises pourraient-elles bénéficier de ces avancées ?
Organisations : quel est votre degré de maturité numérique ?
Authors: Grange Camille , Ricoul Stéphane 
Published: March 2017

En quoi consiste la maturité numérique ? Comment la mesure-t-on ? Est-elle un préalable à une transformation numérique efficace des organisations ou constitue-t-elle un aboutissement en soi ? Et pourquoi est-il si important d’en acquérir ?
Prolonged Ischemia Triggers Necrotic Depletion of Tissue-Resident Macrophages To Facilitate Inflammatory Immune Activation in Liver Ischemia Reperfusion Injury
Authors: Yue Shi , Zhou Haoming , Wang Xuehao , Busuttil Ronald W. , Kupiec-Weglinski Jerzy W. , Zhai Yuan 
Published: March 2017

AbstractAlthough mechanisms of immune activation against liver ischemia reperfusion (IR) injury (IRI) have been studied extensively, questions regarding liver-resident macrophages, that is, Kupffer cells (KCs), remain controversial. Recent progress in the biology of tissue-resident macrophages implicates homeostatic functions of KCs. This study aims to dissect responses and functions of KCs in liver IRI. In a murine liver partial warm ischemia model, we analyzed liver-resident versus infiltrating macrophages by FACS and immunofluorescence staining. Our data showed that liver immune activation by IR was associated with not only infiltrations/activations of peripheral macrophages, but also necrotic depletion of KCs. Inhibition of receptor-interacting protein 1 (RIP1) by necrostatin-1s protected KCs from ischemia-induced depletion, resulting in the reduction of macrophage infiltration, suppression of proinflammatory immune activation, and protection of livers from IRI. The depletion of KCs by clodronate liposomes abrogated the effect of necrostatin-1s. Additionally, liver reconstitutions with KCs postischemia exerted anti-inflammatory/cytoprotective effects against IRI. These results reveal a unique response of KCs against liver IR, that is, RIP1-dependent necrosis, which constitutes a novel mechanism of liver inflammatory immune activation in the pathogenesis of liver IRI.
Targeting Neutrophilic Inflammation Using Polymersome-Mediated Cellular Delivery
Authors: Robertson James D. , Ward Jon R. , Avila-Olias Milagros , Battaglia Giuseppe , Renshaw Stephen A. 
Published: March 2017

Abstract
Neutrophils are key effector cells in inflammation and play an important role in neutralizing invading pathogens. During inflammation resolution, neutrophils undergo apoptosis before they are removed by macrophages, but if apoptosis is delayed, neutrophils can cause extensive tissue damage and chronic disease. Promotion of neutrophil apoptosis is a potential therapeutic approach for treating persistent inflammation, yet neutrophils have proven difficult cells to manipulate experimentally. In this study, we deliver therapeutic compounds to neutrophils using biocompatible, nanometer-sized synthetic vesicles, or polymersomes, which are internalized by binding to scavenger receptors and subsequently escape the early endosome through a pH-triggered disassembly mechanism. This allows polymersomes to deliver molecules into the cell cytosol of neutrophils without causing cellular activation. After optimizing polymersome size, we show that polymersomes can deliver the cyclin-dependent kinase inhibitor (R)-roscovitine into human neutrophils to promote apoptosis in vitro. Finally, using a transgenic zebrafish model, we show that encapsulated (R)-roscovitine can speed up inflammation resolution in vivo more efficiently than the free drug. These results show that polymersomes are effective intracellular carriers for drug delivery into neutrophils. This has important consequences for the study of neutrophil biology and the development of neutrophil-targeted therapeutics.
Why switch to Rental? Costing of Laundry Services at an Apex Tertiary Care Hospital from the View of Outsourcing based on Rental Linen Management Services
Authors: Tadia VK , Ahlawat R , Gupta, SK , Arya, SK , Lathwal, A , Jain, K 
Published: March 2017

ABSTRACT

Introduction
Modern hospitals are matrix organizations with a high investment in terms of capital, labor, and resources. It is imperative for the hospital administration to provide right material of right quality at the right time. Hospitals that set up in-house laundry operations generally make the decision without thoroughly identifying and accounting for total linen and laundry costs. Now evidence has emerged that hospitals that outsource were seeing improved linen utilization rates. If proper and clean linen is not provided, this can result in patient dissatisfaction. Further, innovations in laundry equipment have led to tremendous increases in efficacy. So, there is a need to ascertain the cost incurred in providing linen and laundry services so as to gauge the plausibility of transitioning to outsourcing-based models.

Aims and objectives
To study the cost incurred in providing linen and laundry services at an apex tertiary care hospital and to evaluate outsourcing model based on rental linen management.

Materials and methods
A descriptive, cross-sectional, retrospective, record-based study was conducted during a period of 1 month from March 1, 2016 to March 31, 2016.

Observations
The quantity of monthly linen washed in Dr Rajendra Prasad Centre was found to be 22,465 kg. The monthly laundry expenditure in Dr RP Centre was Rs. 1,415,295. The linen procurement expenditure per month at Dr RP Centre was Rs. 419,386. So total expenditure on linen and laundry per month at Dr RP Centre was Rs. 1,834,681. Thus, cost/kg (with inclusion of linen cost) was Rs. 82.

Discussion and conclusion
The rate quoted by a leading vendor to supply washed, sterilized linen to the hospital was Rs. 55 per kg. Since the expenditure incurred per kg at Dr RP Centre was Rs. 82, this amounted to a saving of around Rs. 27 per kg. It would mean saving of around Rs. 606,555 per month and Rs. 7,278,660 per annum. So, it was recommended that rental linen management services may be hired for Dr RP Centre after taking care of functional, operational, and strategic contingency.

How to cite this article
Tadia VK, Gupta SK, Arya SK, Lathwal A, Jain K, Ahlawat R. Why switch to Rental? Costing of Laundry Services at an Apex Tertiary Care Hospital from the View of Outsourcing based on Rental Linen Management Services. Int J Res Foundation Hosp Healthc Adm 2016;4(2):79-88.
High-resolution coherent backscatter interferometric radar images of equatorial spread F using Capon's method
Authors: Rodrigues Fabiano S. , de Paula Eurico R. , Zewdie Gebreab K. 
Published: March 2017

Abstract. We present results of Capon's method for estimation of in-beam images of ionospheric scattering structures observed by a small, low-power coherent backscatter interferometer. The radar interferometer operated in the equatorial site of São Luís, Brazil (2.59° S, 44.21° W, −2.35° dip latitude). We show numerical simulations that evaluate the performance of the Capon method for typical F region measurement conditions. Numerical simulations show that, despite the short baselines of the São Luís radar, the Capon technique is capable of distinguishing localized features with kilometric scale sizes (in the zonal direction) at F region heights. Following the simulations, we applied the Capon algorithm to actual measurements made by the São Luís interferometer during a typical equatorial spread F (ESF) event. As indicated by the simulations, the Capon method produced images that were better resolved than those produced by the Fourier method. The Capon images show narrow (a few kilometers wide) scattering channels associated with ESF plumes and scattering regions spaced by only a few tens of kilometers in the zonal direction. The images are also capable of resolving bifurcations and the C shape of scattering structures.
REGIÃO METROPOLITANA DE GOIÂNIA: ANÁLISE DA DISPOSIÇÃO ESPACIAL DOS RECURSOS FINANCEIROS PROVENIENTES DE CONVÊNIOS COM O GOVERNO FEDERAL ENTRE 2009 E 2011
Authors: Ribeiro Viana Juheina Lacerda 
Published: March 2017

O artigo discute a distribuição de recursos provenientes de convênios entre os municípios da Região Metropolitana de Goiânia (RMG) e o Governo Federal por intermédio dos Ministérios da Saúde, Educação, Turismo e Cidades entre 2009 e 2011. Os convênios são analisados como mecanismos capazes de promover a integração metropolitana por meio da disponibilidade de serviços de interesse comum ou mesmo da execução de obras de infraestrutura. Para atingir os objetivos foi realizada análise bibliográfica e documental, coleta de dados secundários e mapeamento das informações. A distribuição espacial dos recursos nos permite concluir que, tal qual o padrão de dispersão da população e da infraestrutura urbana, os recursos provenientes são centralizados em municípios com maior demanda e também maior grau de burocratização das administrações municipais.
Prospective Evaluation of Intra-Articular Dextrose Prolotherapy for Treatment of Osteoarthritis in Dogs
Authors: Sherwood J. Matthew , Roush James K. , Armbrust Laura J. , Renberg Walter C. 
Published: March 2017

ABSTRACT
The objective of this study was to evaluate intra-articular dextrose prolotherapy for osteoarthritis of the elbow or stifle in dogs in a randomized, double-blind, placebo-controlled, prospective pilot study. Seventeen dogs were evaluated with 10 meeting inclusion criteria for this study. Evaluations included orthopedic exam, visual lameness scoring, Canine Brief Pain Inventory (CBPI), goniometry, kinetic gait analysis, and radiography. Initial lameness score, age, body weight, duration of lameness, and CBPI scores did not differ between groups. Change in CBPI pain severity score in the prolotherapy group from wk 6–12 was significantly less improved than in the placebo group, with no other significant differences in pain severity or pain interference scores between groups. Range of motion and radiographic scores did not differ between groups at any time. Mean kinetic forces improved in prolotherapy dogs but were not significantly different between treatment groups at any time. Although easily performed and well-tolerated, there were no statistically significant benefits of dextrose prolotherapy for treatment of osteoarthritis of the elbow and stifle in dogs. Post hoc power analysis of these sample means and standard deviations found that 29–106 animals per group would be necessary to demonstrate significant differences in kinetic forces, providing useful guidance for future studies.
Nuevos Reportes de Arrecifes Coralinos en el Caribe de Honduras
Authors: Alegría Andrés , Pérez Cristhian 
Published: March 2017

La exploración de los arrecifes coralinos en el Caribe hondureño ha sido enfocada principalmente en las inmediaciones de las Islas de la Bahía y de los Cayos Cochinos, mientras que mucho menos se conoce sobre la distribución, extensión y salud de estos ecosistemas a lo largo de la plataforma continental dentro de los primeros 10 km de la costa. Sin embargo, la pesca cotidiana de especies asociadas a arrecifes (e.g. Lutjanus synagris, Ocyurus chrysurus) capturadas cerca de la costa por los pescadores artesanales es evidencia sobre la presencia de arrecifes coralinos agregados a lo largo de la plataforma continental. Tras una exploración inicial dentro y alrededor del Refugio de Vida Silvestre Barras de Cuero y Salado identificamos 15 sitios con cobertura bentónica arrecifal previamente no documentada.Ceiba, 2016. Volumen 54(2):157-166
Advances in anticoagulation management of patients undergoing cardioversion of nonvalvular atrial fibrillation
Authors: Bonou Maria , Toutouzas Konstantinos , Diamantopoulos Panagiotis , Viniou Nora , Barbetseas John , Benetos Georgios 
Published: March 2017

SummaryAtrial fibrillation (AF) is a major cause of stroke. The restoration of sinus rhythm through cardioversion, either chemical or electrical is a common practice. Interestingly, there is an incremental increase from the baseline risk for embolisation in the immediate post-cardioversion period, with most events occurring within 10 days from cardioversion. Especially patients with recent onset AF show the lowest rates of antithrombotic therapy, while having a high stroke risk. Despite the increased risk for embolisation, anticoagulation in patients undergoing cardioversion of atrial fibrillation is often inadequate. Moreover, since the implementation of non-vitamin K antagonists oral anticoagulants (DOACs) there are several therapeutic approaches for pericardioversion anticoagulant therapy and not all suits to all patients. In addition, the extensive use of transesophageal echocardiography provides an alternative strategy, especially useful for patients of high haemorrhagic risk. In this review article, we aim to provide an update on the anticoagulation strategies for patients undergoing cardioversion of non-valvular atrial fibrillation in the advent of the use of DOACs.
Physiotherapy Treatments in Musculoskeletal Pathologies Associated with Haemophilia
Authors: Guodemar-Pérez Jesús , Ruiz-López Montserrat , Rodríguez-López Elena , García-Fernández Pablo , Hervás-Pérez Juan Pablo 
Published: March 2017

SummaryThe aim of this study is to offer physiotherapists a synthesis of the main therapeutic tools available for the treatment of musculoskeletal pathologies in patients with haemophilia, according to the scientific literature. Although bleeds are recognised as no longer being a cause of death for people with haemophilia, the accompanying musculoskeletal injuries now represent the main problem associated with this disorder. There is a lack of clear guidelines to date regarding the physiotherapy treatment of these disorders. We performed a keyword searches of Pubmed, Scopus, Sciencedirect, Cochrane and PEDro databases. In total, 555 references were retrieved, of which only 55 fulfilled the inclusion criteria. Publications were grouped by the main symptoms caused by haemophilia and the physiotherapy treatments available. The literature reviewed shows that physiotherapists have a range of therapeutic tools at their disposal for the treatment of the main musculoskeletal disorders suffered by patients with haemophilia. Physiotherapy interventions act upon inflammation and pain, as well as favouring the reabsorption of haematomas, preventing muscle fibrosis and joint ankylosis and recovering the joint range from prior to the lesions. Also, these interventions help prevent muscle atrophy and provide patients with the optimal physical conditions for facing the small and repetitive injuries that, over time, can have a detrimental effect on their quality of life. Conclusion: Haemophilic patients suffer from a series of musculoskeletal disorders, which are associated with important functional disability. Physiotherapy and adapted sports are essential for decreasing disability and improving the quality of life of affected patients.
Evaluation of the impact of osteopathic techniques and physical exercises on the range of motion and sensation of pain in the frozen shoulder - a case report
Authors: W. Romanowski Mateusz , Dwornik Michał , Kwaśniewska Anna , Nowacka Katarzyna , Samborski Włodzimierz 
Published: March 2017

ABSTRACT: This research presents the case of a patient with a frozen shoulder and assesses the impact of osteopathic techniques and physical exercises for this condition. The article describes the epidemiology, etiology, pathogenesis, clinical symptoms and treatment options for frozen shoulder. It also contains information on how to conduct clinical tests and diagnosis of the adhesive capsulitis. We assessed the range of flexion, external rotation, internal rotation and the intensity of pain of the patients frozen shoulder. In this case study frozen shoulder developed typically, in three stages “freezing”, “frozen”, “thawing”. The treatment significantly increased the range of motion of the shoulder joint and reduced sensation of pain. The analysis shows that the osteopathic techniques and physical exercises are an effective form of rehabilitation and pain management. Further studies are needed in this area.
Une approche énactive du développement des compétences en milieu scolaire
Authors: Terré Nicolas , Sève Carole , Saury Jacques 
Published: March 2017

Cet article propose d’explorer d’autres voies que celles des conceptions théoriques dominantes de la compétence. À cette fin, nous commençons par délimiter le « challenge conceptuel » que représente la tenue des postulats de l’énaction dans la description du développement des compétences. Puis, à la suite d’une étude empirique menée auprès de lycéens au cours d’une séquence d’éducation physique (Terré, 2015), le développement des compétences est analysé à partir de l’expérience des élèves. Des hypothèses explicatives sont proposées pour esquisser les contours d’une conception énactive du développement des compétences dont la caractéristique majeure est de considérer l’ancrage du développement des compétences – et conjointement de la pérennité des connaissances – dans des histoires. C’est en s’engageant dans des histoires que les actions et les interprétations des élèves prennent une épaisseur temporelle et qu’ils construisent des « dispositions à agir » constitutives de compétences. Cette analyse se poursuit par la proposition d’inverser la relation généralement établie entre la construction de connaissances et le développement de compétences : les connaissances construites au cours de ces épisodes seraient le produit de la compétence en développement, et non l’inverse. À titre spéculatif, plusieurs axes de transformation des pratiques d’enseignement sont proposés pour favoriser l’engagement des élèves dans des histoires.
Évaluer des compétences : un jugement d’adaptabilité
Authors: Chauvigné Christian 
Published: March 2017

En s’appuyant sur le concept de « schème » (Piaget, 1967) pour définir la compétence comme « organisation invariante de la conduite pour une classe de situations données » (Vergnaud, 1990), la problématique de l’évaluation des compétences, déjà très documentée, ouvre à de nouvelles interrogations et perspectives, qu’il s’agisse de développer ces compétences ou de valider socialement leur acquisition.
L’une des caractéristiques de la compétence ainsi définie est d’être doublement adaptative : son organisation permet l’adaptation aux situations et sa mise en oeuvre, dans l’activité, permet l’adaptation de son organisation. Ainsi, les compétences ne cessent d’évoluer en fonction des activités déployées par les sujets. Il en découle qu’il existe toujours différentes manières d’être compétent et que chaque sujet développe de manière spécifique ses compétences. Par ailleurs, toute évaluation dans ce registre est non seulement diagnostique, mais aussi pronostique; reconnaître une compétence comme « acquise » suppose toujours de faire un pari sur l’extension de l’organisation de l’activité constatée à des situations non testées, voire non connues. Analysée sous cet angle, l’évaluation des compétences procède d’un jugement sur l’adaptabilité du construit cognitif constaté, tandis que la certification des compétences procède d’un jugement d’acceptabilité portant sur cette adaptabilité pour un champ d’intervention donné.