bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal correlates of intuition and cognitive control in moral decision, making in different social contexts
Authors: Keshvari F. , Rezvani Z. , Ghassemi F. , Pouretemad H. 
Published: May 2016

In the stream of flurry of publications grappling different paradigms to tackle underlying mechanisms of moral decision-making, EVENT RELATED POTENtial (ERP) studies is beginning to explore psychophysiological components in the moral domain, focused on observing various moral behaviors in the experimental situations. This research was aimed at providing a new method of study investigating neural correlates of subjective moral decision-making in which we hypothesize that the social congruent or in-congruent context, could emerge a salience brain response in intuitive or cognitive control related responses toward moral dilemmas. Electrophysiological data were recorded from the scalp a 32-channel recording system complying with the international 10–20 system. The average N2 (175–300 ms) and LPP (300–600 ms) amplitude and latency were measured after the onset of putative counterpart response. Repeated measure ANOVA revealed that there was a difference between congruent versus in-congruent social response to high conflict scenarios in LPP amplitude in right lateral and frontal electrodes F(4, 174) = 5.812, P < 0.001 (Fig. 1). The findings also, suggest that N2 latency in less conflict moral scenarios may appear earlier compared with high conflict moral scenarios during in congruent social response in frontal electrodes especially left area F(3, 174) = 3.013, P < 0.05 (Fig. 2, figures are not available for this abstract). In conclusion, these results were either extend previous neurophysiological findings on classic moral scenarios and consistent with the notion that right hemisphere would be much more representative of cognitive control process during high conflict moral decision-making, while left frontal electrodes engaged in early intuitive process.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Brief psychotherapy in eating disorders
Authors: Garcia E. , Leon M. , Polo F. , Martinez R. 
Published: May 2016

First time we began to work with eating disorders, we used to hear the chronic course of the illness and the long-term treatment that our patients would need. When you have a team trained in brief psychotherapy, but not in this specific area, it sounds as just the opposite you try to reach with your patients. National guidelines however are full of psycho-educational and cognitive-conduct treatment's models, without any other validated kind of treatment. However, it was our experience that solution focused or problem focused therapy were also two clinical effective approaches to many psychiatric problems. In fact, we had a mature consult, in which as far as two thirds of patients had become, some way chronic. Problem was, as far as we can imagine, if that was a disease's effect or a lack of a deeper intervention, which were wider than those classic. So, we classified our patients in resistant or not resistant, and doing so we add brief therapy to the first group, reevaluating every week each intervention and the course of the illness. By doing so, we found that chronicity was, in same cases, just the result of limited treatments. Here we have analysed some chronic patients with a bad course and the alternatives that let them to recover.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Misuse of trihexyphenidyl: Factors associated to the prescription
Authors: Hajji K. , ilyes M. , Soumaya F. , Samira Y. , mohamed N. 
Published: May 2016

IntroductionTrihexyphenidyl (THP) is an anti-Parkison and anticholinergic drug. It is essentially prescribed by psychiatrists in order to treat abnormal movements and Parkinsonism induced by antipsychotics. However, in unusual practice, the THP is widely used by patients.AimsTo assess different factors associated to the prescription of trihexyphenidyl in patients treated with neuroleptics.MethodsA cross-sectional, descriptive, comparative and analytical study among 153 patients followed in outpatients clinics and treated by antipsychotics.ResultsDuring a six-month period, 153 patients were interested by the study. In total, 79.73% of them were receiving a treatment by THP. Mean age was 47.79 years old. Almost patients were married (44.1%), having a primary level education (46.7%) and jobless (66.7%). Mean factors associated to THP prescription were: hospitalization in a psychiatry unit (P = 0.025), good evolution of mental disorder during hospitalization (P = 0.008), regular follow-up (P = 0.005), episodic evolution and existence of residual symptoms (P = 0.001), personality disorder (P = 0.025) and somatic comorbidities (P = 0.001). Prescription was crucial in order to indicate necessity of THP. Doses of neuroleptics were a determinant factor (P = 0.0001). Forty-one percent of patients were receiving more than one treatment (P = 0.0001). In most cases, prescription consists of classic antipsychotics (67.60%).ConclusionPrescription of THP should be argued, considering different factors associated to the prescription, in order to prevent misuse of the drug.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Some side effects of antipsychotics
Authors: Montes Reula L. , Ballesteros Prados A. 
Published: May 2016

BackgroundPharmacological treatments for chronic diseases cause side effects. It is important to identify which of these effects could be avoided because it is a cause to drop the treatment. In the chronic psychiatric illness, one of the problems is the induction of changes in prolactin (PRL) serum.PurposeReview of the literature that has been published to assess the association between different types of antipsychotic drugs and prolactin levels.MethodLiterature search on PubMed, NCBI literature in the last three years using MeSH terms: “prolactin” and “antipsychotics”.ConclusionsThe increase of prolactin is a common effect poorly studied in the past. After several studies have been able to achieve treatments, called “atypical”, which cause less effect on this substance. For example, asenapine, olanzapine and zyprasidone have a slight effect on PRL levels. Aripripazole could even result in lower levels probably by partial agonism on dopamine receptors. Therefore, we have to make a good clinical practice taking into account the effectiveness and tolerance and interpersonal variation.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Depressive pseudodementia in Greek patients: How differential diagnosis can lead to early diagnosis
Authors: Lyrakos G. , Tsioumas N. , Spinaris V. , Margioti E. , Sakka P. , Spyropoulos I. 
Published: May 2016

BackgroundThe term Pseudodementia, as presented by Kiloh, is being used to describe the clinical image characterized by depression combined with impairment in cognitive functions which reacts positively in treatment with antidepressants.AimTo explore the aspects that make this condition unique, so that mental health professional will be able to use the proper psychometric tools when they face patients with confusing symptoms.MethodHundred and thirty-one participants were recruited from the B’ Psychiatric Clinic of G.H.N.P “Agios Panteleimon” and Day Center of Alzheimer's Disease in Amarousion, with 56 (42.7%) males and 75 (57.3%) females. All participants were administered the MoCA and the DASS21 questionnaires. Statistical analysis was performed with SPSS21.ResultsThe findings reported a significant difference in the scores of MoCA done by patients with dementia (M = 13.9, SD = 5.4) and patients with depression (M = 20.5, SD = 4.9) while both groups scored below the accepted scores indicating cognitive impairment [CI]. However, analysis showed that in the following sectors of MoCA, depressive patients scored significantly higher than demented ones: visuospatial (MD = 0.651), clock (MD = 1.288), orientation (MD = 1.212) and delayed recall (MD = 1.329).ConclusionFindings shows a significant pattern in the difference between depressed and patients with cognitive impairment. These findings suggest that mental health professionals should use neuropsychological measurements like MoCA when evaluating such cases in order to be able to diagnose effectively cases of pseudodementia.Disclosure of interestThe authors have not supplied their declaration of competing interest.
The effect of relaxation techniques and trigger points therapy on stress reduction of patients with mental health disorders in a Greek hospital
Authors: Lyrakos G. , Menti D. , Spyropoulos I. , Spinaris V. 
Published: May 2016

BackgroundPatients with mental health disorders usually suffer from high stress levels. Trigger points therapy has been shown to be very effective in providing prompt relief from stress in these patients.AimTo investigate the effect of the combined use of relaxation techniques and trigger points therapy on stress levels of patients with mental health disorders.MethodThirty-one patients participated in this study, 14 (45.2%) males and 17 (54.8%) females, with a mean age of 39. Out of them, 10 (32.3%) suffered from anxiety disorders, 6 (19.4%) from obsessive compulsive disorder, 10 (32.3%) from depression and 5 (16.1%) from chronic condition stress. Data analysis was conducted with t-test analysis and ANOVA, using the SPSS software.ResultsThe findings revealed significant differences on stress levels before and after the use of relaxation techniques and trigger points therapy as t(30) = 18.316, P < 0.0001. Before the use of relaxation techniques and trigger points therapy, individuals reported higher stress levels (M = 6.129, SD = 1.087) compared to after the therapy (M = 1.741, SD = .889). Moreover, significant differences were found in stress reduction with regard to psychiatric illnesses (F(3,27) = 5.027, P = 0.007). More specifically, individuals with depression reported lower reductions in their stress levels after the therapy compared to both those with chronic condition stress (M = –2.1, SD = 0.61, P = 0.013) and anxiety disorders (M = –1.4, SD = 0.503, P = 0.05).ConclusionThe findings of this study highlight the importance of using trigger points therapy, combined with relaxation techniques, to reduce stress levels of patients with mental health disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.
The utility of omega-3 fatty acids in depression
Authors: Quintanilla M.A. , Salas A. , Pedrosa S. , Bosqued L. , Perez C. , Villagrasa B. , Aguado B. , Gracia P. 
Published: May 2016

IntroductionRecent studies have reported therapeutic benefit from the use of omega-3 fatty acids (EPA and DHA) as adjunctive treatment of depression.ObjectivesThe goal of this work is to assess the effectiveness and tolerability of dietary supplementation with omega-3 in the treatment of depressed patients.MethodProspective, descriptive, observational study in a general psychiatry outpatient clinic. Consecutive inclusion of depressed patients started on dietary supplementation with omega-3 because of partial response to antidepressants and/or intolerance to high doses or combination of antidepressant drugs between January and May 2015. Sociodemographic variables, clinical data and information about tolerability were recorded. Clinical response to treatment over time was assessed at 4–6 months follow up using the 5-item CGI (Clinical Global Impression) scale.ResultsWe included 30 depressed patients started on omega-3. None of them reported side effects. Seventy-three percent of patients reported clinical improvement (40% much improvement, 33% some improvement). None of them got worse. We did not find association between clinical response and age, sex, type of depression nor duration of illness.ConclusionDespite the limitations of this study, our work support previous positive results on the use of omega-3 fatty acids (EPA and DHA) as adjunctive treatment of depression. Giving the safety of its use, clinicians might recommend omega-3 as adjunctive treatment of depression in cases with a partial response to antidepressants.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Codependency in mothers of addicted persons: Cross-cultural differences between Greece and Bulgaria
Authors: Giannouli V. , Ivanova D. 
Published: May 2016

IntroductionThe people who maintain close relationships with relatives suffering from addiction to psychoactive substances may become more sensitive to develop a physical, mental and emotional state, similar to an emotional addiction.ObjectiveThe aim of this study is to give a cross-cultural perspective to codependence and reveal the profile of female relatives of addicted persons in Greece and Bulgaria.MethodThirty-nine Greek mothers of addicted persons from Greece (Mage = 43.97, SDage = 18.34, all high school graduates), a similar group of forty Greek female participants (32 mothers of non-addicted persons, Mage = 40.97, SDage = 17.22, all high school graduates), and thirty Bulgarian women (all mothers of addicted persons, Mage = 53.55, SDage = 5.58, all high school graduates) were examined with the STAI-state questionnaire, the ZUNG Self Rating Depression Scale and the Questionnaire of Establishment of Codependency.ResultsResults indicated that there are statistically significant differences between the Greek and the Bulgarian female relatives of addicted persons on the scores ofZUNG (MGreek = 51.64, SDGreek = 2.07, MBulgarian = 73.63, SDBulgarian = 4.04) and STAI (MGreek = 53.89, SDGreek = 2.68, MBulgarian = 74.16, SDBulgarian = 4.84), but not for the Questionnaire of Establishment of Codependency. Statistically significant differences in all three questionnaires were found for the groups of Greek mothers of dependent and non-dependent persons (P < .005).ConclusionsThis research suggests that although there is more anxiety and depression reported by the Bulgarian mothers of addicted persons, no cross-cultural difference was found for codependence in mothers of addicted persons.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Acute psychosis induced by short-term treatment with methylprednisolone – a case report
Authors: Andrei I.A. , Cristache A.M. , Parfene-Banu M.E. , Frunză A.A. , Boer M.C. , Puiu M.G. , Patrichi B.E. , Manea M. 
Published: May 2016

Steroid treatment has been widely used for immunologic and inflammatory disorders. Psychiatric symptoms are not uncommon complications of the corticosteroid treatment. Correlations between the hypothalamic-pituitary-adrenal (HPA) axis and various psychoses have been already established in the specialty literature (modified HPA activity by drugs or not, glucocorticoid receptors downregulation, reduced hippocampal volume). The prevalence of corticosteroid-induced psychotic disorders varies around 5–6%. Most corticosteroid-induced symptoms start during the first few weeks after treatment initiation, but their onset can also be in the first 3–4 days. We would like to report the case of a 30-year-old woman who was taken to the psychiatry emergency room for psychomotor agitation, auditory and visual hallucinations, and bizarre delusions, disorganized thinking and modified behavior. The patient had no personal or family history of psychiatric illness. One month earlier, she was admitted in a neurosurgery ward and underwent lumbar surgery for L4–L5 disc protrusion; at discharge, eight days later, she began treatment with methylprednisolone 80 mg/day for three days. One week later, psychotic symptoms emerged that resulted in her hospitalization in our ward for apparent steroid-induced psychosis. Treatment with risperidone (up to 6 mg/day) and diazepam (10 mg/day, rapidly discontinued) was initiated. The endocrinology examination revealed modified plasmatic cortisol. The psychosis resolved several weeks later and the patient was discharged. Psychiatric complications induced by steroids underline the role of physicians that have to educate the patients and their families about these side effects and their early recognition.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Typical profiles of multiple DWI indivisuals on MMPI-2
Authors: Shim I.H. , Woo W.S. , Seo H.J. , Jon D.I. , Kwon Y.J. , Lee K.H. , Min K.J. , Yoon B.H. , Lee J.H. , Lim E. , Bahk W.M. 
Published: May 2016

IntroductionAlcohol intoxication is often involved in the commission of criminal behaviors that are risky and involve personal confrontation. Individuals who reported having three or more drinks before driving exhibited greater impulsivity when under the influence of alcohol than did those who did not report heavy drinking before driving.ObjectivesThe present study utilized the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) to compare the characteristics of individuals with a single driving while intoxicated (DWI) offense with individuals who were multiple DWI offenders and to identify whether there was a typical profile for multiple offenders.MethodsThe charts of patients were examined in terms of demographic characteristics including age, sex, employment, and education; the MMPI scores of the two groups were compared using an independent t-test, and we identified the typical profile of multiple DWI offenders by using hierarchical cluster analysis with Ward's method.ResultsScores on the F and the depression (D) scales of the MMPI-2 were significantly higher among multiple offenders than among first offenders. The multiple offenders-I group obtained relatively high scores on the D and psychopathic deviate (Pd) scales, and the multiple offenders-II group had low scores on both the hypomania (Ma) and social introversion (Si) scales. Thus, some multiple offenders may have poorer emotional adjustment, characterized by tendencies toward psychopathic deviance, mania, and depression, as well as psychopathological characteristics associated with patients with alcohol-use disorders.ConclusionThe present findings suggest that multiple offenders should be considered a high-risk group for alcohol-use disorders and recurrent drunken driving.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Excerpt from the history of the “Hochschulpsychiatrie Erlangen” (1818–2016): On the history of a connection between University and Institutional Psychiatry, Unique in Germany (1903–1974)
Authors: Braun B. , Kornhuber J. 
Published: May 2016

ObjectiveTo examine the more than 70-year history of a connection between University and Institutional Psychiatry.MethodRelevant archival material as well as primary and secondary literature were examined.ResultsAs early as 1818 Johann Michael Leupoldt (1794–1874) held a seminar on “madness” as an assistant professor in Erlangen. But the University Psychiatric Clinic did not begin until 1903 within the association of the mental asylum founded on a contract agreement between the Friedrich-Alexander, University Erlangen and the County Senate of Middle-Franconia. The history of the “Hochschulpsychiatrie Erlangen” reflects part of the history of German psychiatry. The plans to accomplish independence were doomed to impracticability by the social-political situation before, during and after the First and also Second World Wars. Clinic patients were registered as “Institutional residents”, the Clinic had no income of its own, the Head of Department and Director of the Clinic was formally considered as the “senior doctor of the asylum”.DiscussionThe complicated duty dependence of the Head of Department on the Director of the asylum undoubtedly contributed to their decades spanning “mésalliance tradition”. A public scandal arose in 1978 from an accusation of dereliction of duty to the government of Middle-Franconia because of lacking protection of patient documentation and medications during the relocation of the former institution departments to the newly constructed Regional Hospital on the Europakanal.OutlookCooperation between the University Clinic and the Regional Hospital exists in altered form today. The Psychiatric Clinic can thus include patients from the Regional Hospital in scientific studies.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Characteristics of inpatients admitted to National Asylum of Leganés in the early twentieth century (1900–1931)
Authors: Candela Ramírez R. , Vázquez de la Torre Escalera P. , Conseglieri Gámez A. 
Published: May 2016

IntroductionLeganés Psychiatric Hospital has been the subject of several studies about its institutional history, clinical activity and demography of its institutionalized population. The first decades of the twentieth century are the less explored years; however, important events for the development and establishment of the discipline of psychiatry happened in Spain during this period.Objectives/aimsTo describe the sociodemographic and hospitalization characteristics of the patients who were admitted to Leganés National Asylum between 1900 and 1931.MethodsThis is a retrospective case series study. We reviewed medical records found in the Historical Archives of Psychiatric Institute Germain (n = 1043) of inpatients admitted between 1900 and 1931. We analyzed sociodemographic and hospitalization related variables of medical records with SPSS v21. We consultedbibliography, such as asylum documents and diverse primary and secondary literature.ResultsMost inpatients were male, single, with an average age of 38 years, came from home and were admitted as fee-paying boarders. Circa 64% of them remained in the institution until death and the average stay was 7.92 years.ConclusionsEven though the Leganés Asylum was born amidst debate on the asylum model, it did not meet the expectations. Among other reasons, it presented serious architectural deficiencies and was unable to classify inpatients according to the French tradition (agitated, dirty, quiet) or to separate populations, such as minors or criminal inpatients, thus becoming a charity institution asylum instead of a therapeutic mental hospital.Disclosure of interestThe authors have not supplied their declaration of competing interest.