bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of abnormal liver blood tests in patients with inflammatory bowel disease
Authors: Scott Jennifer Amy , Mysko Christopher , Purssell Huw , Athwal Varinder S 
Published: September 2024

Liver blood test (LBT) abnormalities are common in people with inflammatory bowel disease (IBD). The majority are self-limiting, with only 5% having clinically significant liver disease. Liver conditions most frequently associated with IBD include primary sclerosing cholangitis, metabolic dysfunction-associated steatotic liver disease and drug-induced liver injury (DILI). A combination of clinical assessment, blood tests and imaging can be used to help establish the causality and severity of abnormal LBTs in people with IBD.The use of immunomodulatory therapies for IBD has increased the incidence of abnormal LBTs. Most cases are self-limiting and clinically significant injury is rare, particularly with the newer therapeutic agents. Azathioprine and antitumour necrosis factor-α therapies have the greatest risk of liver injury. A clear timeline of drug initiation or dose escalation is essential when interpreting abnormal LBTs to identify DILI. Signs of serious liver dysfunction should prompt immediate cessation of the drug. Otherwise, a patient-centred approach is required when deciding on drug alteration, including the assessment of therapeutic efficacy and the availability of alternative treatment options.
Association between state minimum wage and firearm suicides in the USA, 2000–2020
Authors: Merrill-Francis Molly , Dunphy Christopher , Lennon Natalie , Chen May S , Grady Catherine , Miller Gabrielle F , Girod Candace , McCourt Alexander Duncan 
Published: September 2024

BackgroundFirearm suicides constitute a major public health issue. Policies that enhance economic security and decrease community-level poverty may be effective strategies for reducing risk of firearm suicide. This study examined the association between state minimum wage and firearm suicide.MethodsState minimum wage, obtained from Temple’s Law Atlas and augmented by legal research, was conceptualised using the modified Kaitz Index and a continuous variable centred on the federal minimum wage. State-level suicide counts were obtained from 2000 to 2020 multiple-cause-of-death mortality data from the National Vital Statistics System. Log-linear regressions were conducted to model the associations between state minimum wage and firearm suicides, stratifying by demographic groups. Analyses were conducted in 2023.ResultsA one percentage point increase in a state’s modified Kaitz Index was associated with a 0.3% (95% CI −0.6% to –0.0%) decrease in firearm suicides within a state. A US$1.00 increase in a state’s minimum wage above the federal minimum wage was associated with a 1.4% (95% CI −2.1% to –0.6%) decrease in firearm suicides. When stratified by quartile of firearm ownership, the modified Kaitz Index was associated with decreases in firearm suicides most consistently in the two lowest quartiles.ConclusionIncreasing a state’s minimum wage may be a policy option to consider as part of a comprehensive approach to reducing firearm suicides. These findings expand the evidence base for how economic policies may be leveraged to reduce firearm suicides.
Chromosomal diversity in Crematogaster Lund, 1831 (Formicidae: Myrmicinae) from the Amazon rainforest
Authors: Silveira Linda Inês , Teixeira Gisele Amaro , Barros Luísa Antônia Campos , Dergam Jorge Abdala , de Aguiar Hilton Jeferson Alves Cardoso 
Published: September 2024

Crematogaster Lund, 1831 is a speciose ant genus globally distributed and easily recognizable. Although biogeographical theories explain some variation among Neotropical Crematogaster, several taxonomical issues remain unresolved. While cytogenetic approaches can help to delimit species, cytogenetic data are only available for 18 taxa. In this study, classical and molecular cytogenetic analyses were performed on five Crematogaster species from the Brazilian Amazon to identify species-specific patterns. Two different cytotypes, both with 2 n = 22 chromosomes were observed in Crematogaster erecta Mayr, 1866, suggesting the presence of cryptic species, although with different karyotypic formulas. Crematogaster aff. erecta had 2 n = 28, while Crematogaster limata Smith, 1858, Crematogaster tenuicula Forel, 1904, and Crematogaster sp. had 2 n = 38. The telomeric motif (TTAGG) n was found in all five species, and the (TCAGG) n motif was detected in the telomeres of C. limata. This peculiar motif was also detected in the centromeric regions of C. erecta cytotype I. The microsatellite (GA) n was dispersed in the chromosomes of all species studied, which also had a single intrachromosomal rDNA site. The cytogenetic results revealed notable interspecific and intraspecific variation, which suggests different chromosomal rearrangements involved in the origin of these variations, also highlighting the taxonomic value of cytogenetic data on Crematogaster.
Thin layer axion dynamo
Authors: Dvornikov Maxim 
Published: September 2024

AbstractWe study interacting classical magnetic and pseudoscalar fields in frames of the axion electrodynamics. A large scale pseudoscalar field can be the coherent superposition of axions or axion like particles. We consider the evolution of these fields inside a spherical clump. Decomposing the magnetic field into the poloidal and toroidal components, we take into account their symmetry properties. Within a spherical clump, we use a thin layer approximation in the induction and Klein–Gordon equations, where the dependence of the fields on the latitude is accounted for. Then, we derive the dynamo equations in the low mode approximation. The nonlinear evolution equations for the harmonics of the magnetic and pseudoscalar fields are solved numerically. As an application, we consider a dense axion star embedded in solar plasma. The behavior of the harmonics and their typical oscillations frequencies are obtained. We suggest that such small size axionic objects, containing oscillating magnetic fields, can cause electromagnetic flashes, recently observed in the solar corona, contributing to the corona heating.
Vanishing adsorption limit of Riemann problem solutions for the polymer model
Authors: Petrova Yulia , Plohr Bradley J. , Marchesin Dan 
Published: September 2024

We examine the vanishing adsorption limit of solutions of Riemann problems for the Glimm–Isaacson model of chemical flooding of a petroleum reservoir. A contact discontinuity is deemed admissible if it is the limit of traveling waves or rarefaction waves for an augmented system that accounts for weak chemical adsorption onto the rock. We prove that this criterion justifies the admissibility criteria adopted previously by Keyfitz–Kranzer, Isaacson–Temple and de Souza–Marchesin, provided that the fractional flow function depends monotonically on chemical concentration. We also demonstrate that the adsorption criterion selects the undercompressive contact discontinuities required to solve the general Riemann problem in an example model with non-monotone dependence.
A cidade no estuário do rio amazonas: mapeando apagamentos e sobrevivências na convivência com as águas na Cidade de Macapá-AP
Authors: Pontes Louise Barbalho , Garcia Matheus Cleber Melo , Vasconcelos Ana Carolina Souza de 
Published: September 2024

The municipality of Macapá has an unique relation with waters, manifesting itself in its form and lifestyle. The advance of urbanization has “erased” several water bodies from the urban landscape. This research aims to show that this process has also “buried” certain ways of experiencing the municipality. This study seeks to analyze and identify “erasures” and “survivals” in four different periods of the history of the municipality, focusing its analysis on the leisure areas related to waters and their enjoyment. This mapped these leisure spaces and manifestations that are linked to the site and its biophysical conditions, resulting in a cartography that inventories, maps, and classifies its different uses. This study contributes to scientifically describes the fading process of experiencing and accessing the enjoyment of water in the municipality of Macapá.
GPER Stimulation Attenuates Cardiac Dysfunction in a Rat Model of Preeclampsia
Authors: Nogueira de Alencar Allan Kardec , Swan Kenneth F. , Mahapatra Smruti , Lindsey Sarah H. , Pridjian Gabriella C. , Bayer Carolyn L. 
Published: September 2024

BACKGROUND:
Preeclampsia poses a substantial clinical challenge, characterized by maternal hypertension, cardiac dysfunction, and persistent cardiovascular risks for both the mother and offspring. Despite the known roles of the estrogen receptor (GPER [G protein-coupled estrogen receptor]) in placental development, its impact on cardiovascular aspects within a preeclampsia animal model remains unexplored. We propose that G-1, a GPER agonist, could have the potential to regulate not only hypertension but also cardiac dysfunction in rats with preeclampsia.

METHODS:
To explore the influence of G-1 on preeclampsia, we used the reduced uterine perfusion pressure (RUPP) model. RUPP rats were administered either G-1 (100 µg/kg per day) or hydralazine (25 mg/kg per day). We conducted echocardiography to probe the intricate cardiac effects of G-1.

RESULTS:
The RUPP rat model revealed signs of hypertension and cardiac dysfunction and alterations in gene and protein expression within placental and heart tissues. G-1 treatment reduced blood pressure and reversed cardiac dysfunction in rats with preeclampsia. In contrast, administration of the vasodilator hydralazine reduced blood pressure without an improvement in cardiac function. In addition, while G-1 treatment restored the levels of sFLT-1 (soluble fms-like tyrosine kinase-1) in RUPP rats, hydralazine did not normalize this antiangiogenic factor.

CONCLUSIONS:
The therapeutic intervention of G-1 significantly mitigated the cardiovascular dysfunction observed in the RUPP rat model of preeclampsia. This discovery underscores the broader significance of understanding GPER’s role in the context of preeclampsia-related cardiovascular complications.
Mismatches between 3D Content Acquisition and Perception Cause More Visually Induced Motion Sickness
Authors: Xia Zhenping , Liu Yujie , Bai Yi , Zhang Yueyuan , Cheng Cheng 
Published: September 2024

Abstract
The sensory rearrangement theory announced that a mismatch between the current visual inputs and the visual exposure history might trigger or aggravate the visually induced motion sickness (VIMS). However, this has not been explicitly investigated through perception experiments. This study investigates the effect of mismatches between 3D content acquisition and perception on VIMS. Two types of mismatches between the camera field of view and the eye field of view were compared with the match type, and the mismatch types are the conditions that configured the camera field of view to be larger or smaller than the eye field of view. A perception experiment was executed with 21 participants, and the subjective SSQ, five-scale VIMS level rating, and objective postural instability were adopted as the evaluation metrics. The mismatches were found to have a significant effect (p &lt; 0.05) on the VIMS symptom based on the results of subjective VIMS level rating and objective postural instability evaluations. Mismatches between 3D content acquisition and perception cause more VIMS. This knowledge highlights the importance of perfect configuration matches in 3D content acquisition, display, and perception for eliminating the potential VIMS aggravation effect.
The Quasi-Stochastic Nature of Hail Growth: Hail Trajectory Clusters in Simulations of the Kingfisher, Oklahoma, Hailstorm
Authors: Adams-Selin Rebecca 
Published: September 2024

Abstract
Current methods that incorporate synoptic-, mesoalpha-, and even some storm-scale processes to distinguish among storms that produce significantly severe versus merely severe hail have not been highly successful. These results suggest that smaller-scale processes, such as mesobeta, mesogamma, and misoscale, have a larger impact on hail production than previously theorized. Relatedly, previous research, often using hail trajectories driven by steady-state model fields, has also frequently painted hail trajectories as having simple, relatively uniform motions within a supercell. This study uses a Lagrangian hail trajectory model embedded in two idealized supercell simulations and updated every model time step, in conjunction with a trajectory clustering technique, to examine the variability of hail trajectories both within and across the two simulations. The clustering method identified 11 distinct clusters in both supercell simulations. Clusters sourced embryos from almost all quadrants around the updraft core. Trajectories in both simulations exhibited complex and highly variable behavior, occasionally including multiple vertical loops. Cluster trajectories could follow similar paths but produce different distributions of mass at the surface or, conversely, could follow different paths but result in similar mass distributions at the surface. An aggregate review of all trajectories showed the larger hail in each simulation was somewhat more likely to be produced in regions with less strong peak updraft speeds, but other environmental profile information was more mixed, particularly for the simulation producing the largest hail. In sum, storm-scale information is highly impactful on hail trajectories and needs to be considered in forecasting applications. Future hail trajectory modeling studies also need to incorporate more realistic storm-scale information.

Significance Statement
Predicting which storm might produce very large as opposed to merely large hail remains a really hard problem. What if there are processes that affect hail that happen on very small scales that our current models do not see? This study simulates millions of modeled hail trajectories and finds that they are all very different. Even trajectories that start and end at similar places can take completely different paths and end up different sizes. These results suggest that there are many more ways for storms to produce large hail—or fail to do so—than we previously thought, and small-scale processes can have big impacts.
Hepatitis A vaccination in a racially and sexually diverse population of gay, bisexual, and other men who have sex with men: Findings from the QVax study
Authors: Guo Tiffany Y , Halkitis Perry N , Lewis Kendra , Krause Kristen D 
Published: September 2024

Background Previous studies found vaccination uptake of vaccine-preventable diseases (VPD) to be associated with race/ethnicity and medical mistrust among key populations, however, few studies examine Hepatitis A vaccination uptake. Methods This cross-sectional study used online survey data collected from NJ and NY residents identifying as lesbian, gay, bisexual, transgender, queer (LGBTQ+) from October 2021 through November 2022. Results This study used a subsample of 222 gay, bisexual, and other cisgender men, 66.7% White, with mean age 41.22 years (SD = 15.23), and 60% fully vaccinated for Hepatitis A. Overall, average group-based medical mistrust scores did not differ among non-vaccinated participants compared to fully or partially vaccinated participants. However, higher group-based medical mistrust scores were associated with non-White identifying participants, and were highest among Hispanic/Latinx (2.68, sd = 0.43) and Black non-Hispanic (2.58, sd = 0.50) participants ( p < .001). Vaccination patterns did not differ among fear or vaccine confidence-based items. Conclusions Our results contribute to the limited knowledge of differences in Hepatitis A vaccination uptake among men who have sex with men, and support the need for targeted intervention programs that acknowledge the diverse population of LGBTQ + identifying individuals and their associated health behaviors.
Grade 3 cytolysis in a patient with metastatic colorectal cancer consuming a mushroom powder-based alternative therapy
Authors: Strobbe Geoffrey , Jeanjacquot Margaux , Potey Camille , Carnot Aurélien , Marliot Guillaume 
Published: September 2024

Introduction The use of Complementary Alternative Medicine (CAM) in patients with cancer is increasing. CAM is associated with potential toxicity and drug interactions, particularly with chemotherapy. Here, we report a case of cytolysis and hepatic cholestasis in a patient who was self-medicated with a mushroom powder-based alternative therapy containing Agaricus blazei Murril (ABM) during cancer treatment. Case Report A 43-year-old woman with metastatic colorectal cancer and hepatic metastases was admitted to our hospital for intravenous chemotherapy. Markers of hepatic grade 3 cytolysis and cholestasis were identified during the pretreatment consultation. The baseline results were within normal limits. Management and Outcome The chemotherapy was immediately canceled, and further tests were performed. After the investigation, the patient reported taking three mushroom powder-based capsules per day since November 2023. The dietary supplement contained ABM and Hericium erinaceus (HE) powder. After Pharmaceutical analysis, treatment with the supplement was discontinued, and the patient has not resumed. The changes in liver function were also favorable. Discussion In our case, given the improvement in liver function after CAM discontinuation, hepatic cytolysis appeared to be linked to ABM consumption despite the patient's liver metastases. Pharmaceutical analysis of CAM is essential to ensure the safety and optimization of cancer treatments. Patients should also communicate their CAMs to healthcare professionals and be aware of the consequences of consuming these dietary supplements. Finally, collaboration between pharmaceutical teams and oncologists is essential for optimal management of cancer patients.
A comparison of white-to-white measurements obtained by Anterion AS-OCT versus three optical devices in refractive surgery candidates
Authors: Salouti Ramin , Azizi Ali , Hashemian Hesam , Khorrami-Nejad Masoud , Alkhafaji Qassim , Salouti Kia , Ghoreyshi Maryam , Hossein Nowroozzadeh M. 
Published: September 2024

Background and Objectives To assess the agreement between Anterion AS-OCT and three optical devices in measuring the white-to-white (WTW) diameter in candidates for refractive surgery. Methods In this cross-sectional prospective study, 129 right eyes of 129 normal individuals underwent consecutive scans with the Anterion, the Pentacam AXL, the IOLMaster 700, and the Orbscan IIz. Mean difference (MD), 95% limits of agreement (LoA), and concordance correlation coefficient (CCC) were calculated to assess agreement and interchangeability. Results The mean age of participants was 30.4 ± 5.9 (range: 21–47) years. The mean WTW distance measured by the different instruments was as follows: 12.00 ± 0.42 mm (range, 10.57 to 13.05) using the Anterion, 11.87 ± 0.34 (11.10 to 12.80) using the Pentacam, 12.12 ± 0.44 (11.00 to 13.30) using the IOLMaster, and 11.73 ± 0.37 (11.00 to 13.10) using the Orbscan. The MD and 95% LoA for Anterion vs. Pentacam, IOLMaster, or Orbscan were [0.11; −0.31 to 0.54 mm], [-0.13; −0.93 to 0.66], and [0.25; −0.28 to 0.78], respectively. The corresponding CCCs were 0.803, 0.514, and 0.631. Conclusions This study found weak agreement between Anterion and Pentacam AXL, IOLMaster 700, and Orbscan IIz devices regarding WTW distance measurements in refractive surgery candidates. Therefore, it is not recommended to use Anterion's WTW measurements interchangeably with the other three devices, particularly for phakic intraocular lens sizing.
A Disparity
Authors: Adkins-Jackson Paris B. 
Published: September 2024

As a living being that was passed down the role of storytelling, I describe the conditions under which individuals find themselves. Science, and specifically public health research, affords me the opportunity to deploy my storytelling skills toward advocacy and intervention for communities that disproportionately bear the burden of poor health. Although neither role makes space for the emotional toll of this work. Neither allows me to rest long enough to move through the emotional mist of what it means to be perceived as a queer, Black, cisgender woman, and storytelling scientist in a stratified and hateful world where I am so much more. This poem pools from various worlds within me for each stanza. The poem seeks to reconcile for my whole self, and others who experience marginality, why our colleagues, countrypersons, and community members see it fit to perpetuate notions of human difference along racialized, socioeconomic, sexualized, gendered, able-bodied, and other stratified lines—to the detriment of our lives. How can my colleagues, countrypersons, and community members be willing to receive the privileges of a democratic society but discard the lives from which that society was built? How can my colleagues, countrypersons, and community members be willing to receive our science but discard our health? This poem brings together multidisciplinary discourse from the humanities and the social and biological sciences to state plainly what many others have academically. May this poem be paired with existing literature on the falsity of biologized race, reparations, and methodologies of reflexivity in science. To view the original version of this poem, see the Supplemental Material section of this article online.
Varieties of pictorial vision
Authors: Koenderink Jan , van Doorn Andrea , Wagemans Johan 
Published: September 2024

Pictorial awareness is addressed through experimental phenomenology involving over 90 naïve participants. Since one can’t look at the “same” picture twice the study uses one-shot trials. The participant’s fascination for the duration of a session is held through the artistic principle of theme and variation. Six variations focus on the theme of pictorial geometry, both two-dimensional and three-dimensional. Major findings are: Idiosyncratic deviations from veridical are huge as compared to common textbook “effects.” Observers wield arbitrary heuristics for tasks that are “formally related.” The assumption of a common formal framework is apparently unsound. The notion of “inverse optics” is misleading. A fair fraction of the population appears to lack monocular stereopsis as intuitive awareness. It suggests an as-yet unrecognized, but perhaps common variety of aphantasia.