bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Past, Present, and Future of Large‐Scale Assessment Consortia
Authors: Briggs Derek C. 
Published: September 2024

AbstractThis article provides a history of the two large‐scale assessment consortia that were funded in 2010 as part of the Race to the Top Competition, the Partnership for the Assessment of Readiness for College and Career (PARCC), and the Smarter‐Balanced Assessment Consortium (SBAC). I compare the goals the consortia were funded to meet between 2011 and 2015 with the assessment systems PARCC and SBAC were able to deliver. Two notable accomplishments of both consortia were the development of high‐quality summative assessments that were carefully designed to be accessible to all test‐takers. I describe factors that led many states to withdraw from consortia membership between 2011 and 2015, and which led to the effective dissolution of PARCC. I discuss lessons learned from serving on the PARCC and SBAC technical advisory committees, and make a case for the value proposition of assessment consortia in the future.
Fatigue life prediction of additively manufactured AlSi10Mg based on surface roughness and residual stress
Authors: Strauß Lea , Pang Genny A. , Löwisch Günther 
Published: September 2024

AbstractLaser‐based powder bed fusion (PBF‐LB) has gained prominence in the realm of additive manufacturing of metals. This technique utilizes a laser beam to consolidate powder layers, which inherently introduces high thermal gradients and rapid cooling rates. This results in characteristic process effects, including inhomogeneities, surface roughness, anisotropy, and residual stress, which play a pivotal role in altering the fatigue properties of the manufactured components. This paper presents fatigue tests involving samples of AlSi10Mg manufactured using PBF‐LB with varying surface roughness and residual stress. An approach to predict fatigue life based on stress amplitude, residual stress, and crack size is presented, using a smooth sample as a reference. An empirical model for fatigue life prediction is developed from experimentally measured values of fatigue life, peak surface roughness, and residual stress.
Homogenization of fish assemblages in an endemic biodiversity hot spot: Evidence from 70‐year data from the Yun‐Gui Plateau, China
Authors: Shi Lei , Xiang Tao , Dong Xianghong , Xu Chi , Wang Haijun , Jeppesen Erik , Xie Ping 
Published: September 2024

Abstract

The combined impacts of anthropogenic activities and global climate changes threaten native fish communities. Such threats are particularly critical in biodiversity hot spot areas with many endemic species, as exemplified by the isolated Yun‐Gui Plateau, China. The risk of biotic homogenization is also expected to be high in such areas, but this risk and its underlying drivers remain poorly studied.

Here, we established a database of fish distributions and used environmental filtering for spatial clusters (n = 3759) in river basins located at Yun‐Gui Plateau. This database was based on public data sources and a comprehensive review of relevant literature (n = 481) covering the period from 1950 to 2021. We divided the plateau into nine subbasins for spatial comparison and into two periods for temporal comparison—before and after the start of rapid economic growth development in 1978.

We found: (a) a marginal increase in replacement (species exchange in different subbasins) and similarity index but a decrease in richness difference index, indicating homogenization and the loss of natural barriers across the entire plateau; (b) an increase in species richness accompanied by a discernible decline in phylogenetic diversity, also indicating homogenization; (c) the increase in species richness by species loss‐gain analyses was associated with climatic variables (temperature and precipitation), elevation and human activities in all subbasins.

Temporal and spatial comparisons indicated that homogenization of fish assemblages in the Yun‐Gui Plateau was exacerbated by climatic and anthropogenic pressures.

The observed homogenization of fish species is of great concern, and we call for systematic assessments and precautionary mitigation actions to maintain the uniqueness of biodiversity in the Yun‐Gui Plateau region.
Where the wild places are: Factors associated with people's favourite local and national wild place in the United Kingdom
Authors: Madsen Emily K. , Daniels Mike , Montgomery Clara , Stillman Namid , Homer Nick , Lambert Cristín , Hare Darragh 
Published: September 2024

AbstractProtected areas globally serve as crucial sanctuaries for biodiversity, playing a pivotal role in conserving endangered species and maintaining ecological balance. In the United Kingdom (UK), 25% of land is currently designated as public protected areas and discussions are underway regarding the implementation of new protected areas, including the establishment of new National Parks in all four nations of the UK. Wild places have an important role to play in understanding and deciding where public protected areas should or could be. People form profound connections to wild places locally and nationally. We used two online surveys to gather information on the UK public's local and national favourite wild places, and the characteristics of those places which make them their top choice. Our analysis revealed that respondents preferred different wild places based on their survey group, with significant differences in the importance placed on characteristics like ‘Accessibility’, ‘Nature’ and ‘Scenery’ across local and national scales. Demographic factors, including age and settlement, had some impact, but the overall importance of characteristics like ‘Peace and Quiet’ and ‘Nature’ were consistently high across both surveys. Recognising the prevalence of favourite wild places outside of designated areas underscores the importance of engaging the different viewpoints of the public in conservation initiatives, and indicates that public support for conservation might extend beyond officially protected regions.
Hybrid meat products: the physicochemical and microstructural properties of beef meat emulsion produced with jackfruit (Artocarpus heterophyllus) flesh and bamboo (Bambusa polymorpha) shoot as meat substitutes
Authors: Bee Chi Ng , Asyrul‐Izhar Abu Bakar , Sani Muhamad Shirwan Abdullah , Ismail‐Fitry Mohammad Rashedi 
Published: September 2024

SummaryHybrid meat products are a beneficial approach to incorporating plant proteins into conventional meat formulations, taking into account current market trends that emphasise the partial decrease in animal protein content. This study aimed to evaluate the effects of using different percentages of beef meat (BM), jackfruit flesh (JF) and bamboo shoot (BS) as a meat substitute in beef meat emulsion. Emulsion with 100% BM (Control), (A) 50% JF + 50% BM, (B) 50% BS + 50% BM, (C) 50% BM + 25% JF + 25% BS, (D) 100% JF and (E) 100% BS were developed. Six formulations of meat emulsion samples were prepared and analysed in terms of physicochemical and microstructure properties. The substitution of JF and BS in meat emulsion resulted in more stable emulsion stability. The WHC and pH values showed no significant differences (P > 0.05) between samples. The samples with different percentages of JF and BS had significantly increased (P < 0.05) the moisture content and the crude fibre content, however, it significantly reduced (P < 0.05) the crude protein content. No significant difference (P > 0.05) in ash and fat content for the formulated meat emulsions from the control. One hundred per cent BS showed higher lightness (L*), yellowness (b*) and lower redness (a*) values significantly (P < 0.05) compared to the control. One hundred per cent JF and 100% BS depicted significant differences (P < 0.05) for the textural properties and gel strength compared to the control. The scanning electron microscopy (SEM) provided evidence for the microstructure that the higher the percentages of plant‐based ingredients, the smaller the cavities. Overall, the incorporation of 50% BM + 25% JF + 25% BS could produce the best‐suited meat substitution product.
Proliferative mechanism of benign prostatic hyperplasia by NLRP3 inflammasome through the complement pathway
Authors: Hata Junya , Matsuoka Kanako , Harigane Yuki , Yaginuma Kei , Akaihata Hidenori , Meguro Satoru , Honda‐Takinami Ruriko , Onagi Akifumi , Sato Yuichi , Ogawa Soichiro , Uemura Motohide , Kojima Yoshiyuki 
Published: September 2024

ObjectivesThe expressions of complement component C5a and NLRP3 inflammasome and the antiproliferative effect of resveratrol in benign prostatic hyperplasia (BPH) model rat were analyzed to clarify the BPH proliferative mechanism.MethodsThis study used the pathological stromal‐dominant BPH model rat by urogenital sinus implantation (UGS). Expression of C5a, NLRP3, Caspase‐1, IL‐1β, and IL‐18 using rat BPH tissues at 2, 3, and 8 weeks (n = 6, respectively) after UGS implantation were analyzed by qRT‐PCR, western blotting analysis, and immunohistochemical (IHC) analysis. Serum IL‐1β levels in BPH model and sham rats were measured by enzyme‐linked immunosorbent assay. Furthermore, resveratrol, as the NLRP3 pathway inhibitor, was administered to BPH model rat to assess the antiproliferative effect on the BPH proliferative process. The proliferative effect on prostate was evaluated by Ki‐67 protein expression.ResultsThe expression levels of C5a, NLRP3, Caspase‐1, IL‐1β, and IL‐18 in qRT‐PCR, western blotting, and IHC were significantly upregulated in BPH tissues compared to control prostate tissues and showed increases with time (all p < 0.05). Serum IL‐1β levels in BPH model rats had significantly increased compared to sham rats. On IHC, deposition of C5a, NLRP3, Caspase‐1, IL‐1β, and IL‐18 was abundant in stromal areas of BPH. The administration of resveratrol significantly decreased prostate weight and expressions of NLRP3, IL‐1β, IL‐18, and Ki‐67 (all p < 0.05).ConclusionsNLRP3 inflammasome activation by complement C5a produces IL‐1β and IL‐18 through Caspase‐1 during the BPH proliferative process. NLRP3 inflammasome have the possibilities to be a therapeutic target for BPH proliferation by inhibiting the NLRP3 inflammasome pathway.
CCR5‐mediated homing of regulatory T cells and monocytic‐myeloid derived suppressor cells to dysfunctional endothelium contributes to early atherosclerosis
Authors: Akhtar Shamima , Sagar Komal , Roy Ambuj , Hote Milind P. , Arava Sudheer , Sharma Alpana 
Published: September 2024

AbstractA disbalance between immune regulatory cells and inflammatory cells is known to drive atherosclerosis. However, the exact mechanism is not clear. Here, we investigated the homing of immune regulatory cells, mainly, regulatory T cells (Tregs) and myeloid‐derived suppressor cells (MDSCs) subsets in asymptomatic coronary artery disease (CAD) risk factor‐exposed young individuals (dyslipidemia [DLP] group) and stable CAD patients (CAD group). Compared with healthy controls (HCs), Tregs frequency was reduced in both DLP and CAD groups but expressed high levels of CCR5 in both groups. The frequency of monocytic‐myeloid‐derived suppressor cells (M‐MDSCs) was increased while polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSCs) were decreased in CAD patients only. Interestingly, although unchanged in frequency, M‐MDSCs of the DLP group expressed high levels of CCR5. Serum levels of chemokines (CCL5, CX3CL1, CCL26) and inflammatory cytokines (IL‐6, IL‐1β, IFN‐γ, TNF‐α) were higher in the DLP group. Stimulation with inflammatory cytokines augmented CCR5 expression in Tregs and M‐MDSCs isolated from HCs. Activated endothelial cells showed elevated levels of CX3CL1 and CCL5 in vitro. Blocking CCR5 with D‐Ala‐peptide T‐amide (DAPTA) increased Treg and M‐MDSC frequency in C57Bl6 mice fed a high‐fat diet. In accelerated atherosclerosis model, DAPTA treatment led to the formation of smooth muscle‐rich plaque with less macrophages. Thus, we show that CCR5‐CCL5 axis is instrumental in recruiting Tregs and M‐MDSCs to dysfunctional endothelium in the asymptomatic phase of atherosclerosis contributing to atherosclerosis progression. Drugs targeting CCR5 in asymptomatic and CAD risk‐factor/s‐exposed individuals might be a novel therapeutic regime to diminish atherogenesis.
A beautifully preserved comma shrimp (Pancrustacea: Peracarida) from the Plio‐Pleistocene of Japan and the fossil record of crown Cumacea
Authors: Luque Javier , Gerken Sarah 
Published: September 2024

AbstractComma shrimp, or cumaceans, are diverse benthic crustaceans, yet they are one of the groups with the poorest fossil record, hindering our understanding of the evolution of the group in deep time. Here, we describe a new species of fossil comma shrimp, Makrokylindrus itoi sp. nov., from the Plio‐Pleistocene of Japan. The singular fossil is exceptionally preserved, including details of the carapace, cuticle, and some appendages, and it represents the first known fossil of the family Diastylidae and only the fourth fossil crown group cumacean known to date. We suggest that the scarce and sparsely known fossil record of cumaceans likely reflects a lack of recognition due to their small size and unfamiliar anatomy, making fossil cumaceans easy to misidentify, be confused with crustacean larvae of unknown affinities, or be interpreted as fragments of other crustaceans (taxonomic bias), rather than a lack of fossilization potential (taphonomic bias).
‘It's Not Like a One‐Way Street’: Using Photovoice to Understand How College Students With Intellectual Disability Experience Interdependence
Authors: Hoyle Jessica N. , Warren‐Findlow Jan , Wallace Lauren , Laditka James N. , Laditka Sarah B. 
Published: September 2024

ABSTRACTBackgroundMany people view people with intellectual disability primarily as needing help. That perspective limits relationships and can promote discrimination. We sought to better understand social relationships among young adults with intellectual disability.MethodSeven postsecondary students with intellectual disability participated in a photovoice study, sharing photos and stories about giving and receiving help. They participated in individual interviews, a group meeting, and a photo exhibition, and helped identify results and conclusions.ResultsParticipants viewed themselves as helpers and recipients of help. Themes were: foundational importance of families; openness to being helped; personal growth through challenging experiences; and tension between wanting to help and risks of helping others. Participants wanted to raise awareness that people with disabilities can help others, educate them about disability, and contribute to research.ConclusionsMany young adults with intellectual disability want to contribute to relationships, which are often limited by others' expectations about disability.
Negative and Positive Experiences During the COVID‐19 Pandemic in Canadians With Developmental Disabilities: A One‐Year Ontario‐Based Survey
Authors: Kassee Caroline , Jachyra Patrick , Mahalingam Vijitha , Tint Ami , Lin Hsiang‐Yuan , Ameis Stephanie H. , Di Martino Adriana , Lunsky Yona , Lai Meng‐Chuan 
Published: September 2024

ABSTRACTPurposeUnderstanding the experiences of people with developmental disabilities during the initial period of COVID‐19 pandemic.MethodsIndividuals with developmental disabilities and their caregivers completed baseline and up to five follow‐up online surveys using the CRISIS‐AFAR measures, between July 2020 and September 2021. We used qualitative (thematic analysis) and quantitative (MANOVA) analytic methods.ResultsOne hundred and eighteen participants (64 caregivers on individuals 6–62 years, 54 self‐reporting individuals aged 17–55 years) completed baseline survey; 46 participants (23 caregivers, 23 self‐reporting adults) completed ≥1 follow‐up. Qualitative themes included uncertainty, and negative and positive influences on behaviours and routines, daily life and mental wellness. Those experiencing positive impacts did not stably perceive so longitudinally.ConclusionsDespite both negative and positive influences on individuals with developmental disabilities and their families, the prolonged pandemic had wide‐ranging repercussions. Emergency preparedness planning should consider the disruptive effects of public health measures on routine and support for this vulnerable population.
The Potential Effect of Periodontal Disease on the Development of Metabolic Syndrome: A 10‐Year Observational Study in a Thai Adult Cohort
Authors: Ayuthaya Benjar Issaranggun Na , Lertpimonchai Attawood , Samaranayake Lakshman , Vathesatogkit Prin , Thienpramuk Lalitsara , Wisitrasameewong Wichaya , Tamsailom Suphot 
Published: September 2024

ABSTRACTAimAs data are sparse on the long‐term association between periodontal diseases and development of metabolic syndrome (MetS), we investigated their relationship in a Thai cohort over a 10‐year observational period.MethodsMedical records and data on periodontal assessments of 2161 employees of the Electricity Generating Authority of Thailand collected at two time points, 2003 and 2013, were used. Experienced periodontists used standard national and international criteria to define periodontitis and MetS. The impact of baseline periodontitis on subsequent MetS incidence and its components was evaluated using regression analyses.ResultsThe severity and extent of periodontitis significantly predicted MetS incidence over a decade, with a higher incidence of MetS in individuals with poorer periodontal health. A single percentage increase in the periodontitis extent raised the risk of MetS incidence by 0.4% and the risk of developing individual components of MetS by 0.2%. Independent of periodontal health, age of an individual emerged as a factor impacting MetS development.ConclusionThis study highlights the potential effect of the severity and extent of periodontitis on the increased incidence and progression of MetS. Hyperglycaemia and hypertension were the two MetS components most significantly affected by the existence of periodontitis.
Enhancement of fish protein hydrolysates for salad dressing through high shear and sterilization pre‐treatments
Authors: Moreira Thaysa F. M. , de Oliveira Anielle , Rodrigues Vanessa de C. , de Carvalho Amarilis S. , Quichaba Michely B. , Peron Ana P. , Gonçalves Odinei H. , Gozzo Angela M. , Leimann Fernanda V. , Ribeiro Ricardo P. 
Published: September 2024

AbstractThermal and mechanical treatments may affect the structure of hydrolyzed proteins, thus influencing the obtaining of peptides with improved bioactivity. In this work, tilapia muscle was treated by thermal sterilization or homogenization with ultra‐turrax (UT) and hydrolyzed with alcalase to obtain FPHs with antioxidant properties in salad dressing. To evaluate the bioactive potential of FPHs, the acetylcholinesterase inhibition assay was applied, resulting in up to 45.87% inhibition for the UT sample (60 mg/mL). Also, no cytotoxicity was detected by Allium cepa model for all FPHs. The emulsifying activity index and emulsifying stability index of FPHs indicated better emulsifying capacity in basic pH. As a proof of concept, FPHs were used as an emulsifying/antioxidant agent to prepare a salad dressing. FPHs increased the formulation's protein content, pseudoplastic behavior, color, and texture. In addition, FPHs aided the oxidative stability of salad dressing (evaluated by oil's extinction coefficient), demonstrating potential application in emulsified foods by acting on the elimination of radicals generated in lipid oxidation.Practical applicationsFish protein hydrolysates (FPHs) offer diverse bioactive properties such as antioxidant, antimicrobial, anticancer, antihypertensive, and acetylcholinesterase (associated with Alzheimer's disease) inhibitory effects. However, optimizing their technological properties poses a challenge, affecting applicability and bioactivity. Industrial processes such as thermal and mechanical treatments can alter protein structures, influencing peptide bioactivity post enzymatic hydrolysis. This study investigates the impact of substrate pre‐treatments, sterilization via thermal heating, and homogenization using a rotor‐stator system (ultra‐turrax) on FPHs' technological properties after hydrolysis with alcalase, including emulsifying capacity and acetylcholinesterase inhibitory capacity. In addition, it explores the application of pre‐treated FPHs in a real food system (French salad dressing), assessing rheological properties, texture, and oxidative stability. Such evaluations are crucial for ensuring the feasibility of industrial FPHs production and their application.
Association between dietary vitamin C intake and migraine in adults: A cross‐sectional study of the National Health and Nutrition Examination Survey
Authors: Zhao Dehua , Long Xiaoqing , Wang Jisheng 
Published: September 2024

AbstractBackgroundPrevious studies indicate that vitamin C may decrease the occurrence and intensity of migraines, but the evidence is restricted due to small sample sizes. This study aimed to determine the magnitude of the association between dietary vitamin C intake and migraine in the general population.MethodsThis cross‐sectional study utilised data from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999 and 2004. Participants who had severe headaches or migraines in the past 3 months were classified as experiencing migraines. Dietary vitamin C intake was evaluated using the 24‐h dietary recall system. Logistic regression models, restricted cubic spline (RCS) regression and stratified analyses were employed to assess the association between dietary vitamin C intake and migraine.ResultsThe study included 4101 participants, of whom 702 (17.12%) experienced migraine. The study revealed an inverse association between dietary vitamin C intake and migraine (odds ratio [OR] = 0.89, 95% confidence intervals [CI] = 0.83–0.96, p = 0.002) after adjusting for demographic covariates, lifestyle covariates, laboratory tests, physical examinations, physical activity, dietary covariates and comorbidities. When vitamin C intake was categorised, the adjusted OR (95% CI) for migraine in Q4 (highest vitamin C intake) was 0.64 (95% CI = 0.49–0.84, p = 0.001) compared to Q1 (lowest vitamin C intake). The RCS regression showed a linear inverse relationship between dietary vitamin C intake and migraine (pnon‐linearity = 0.449). The findings remained consistent, and no significant interactions were found among different groups.ConclusionsDietary vitamin C intake was inversely associated with migraine, and a linear negative relationship was found between vitamin C intake and migraine.
Measuring the Impact of Unconventional Monetary Policies on the U.S. Banking and Bond Markets at the Lower Bound
Authors: SPENCER PETER 
Published: September 2024

AbstractThe effects of credit and monetary policy shocks are analyzed using a shadow rate model of the Eurodollar (ED) and Treasury bond markets. This model uses three factors common to both markets and two spread factors that capture the term structure of the rate differential. The results show that the policy initiatives that followed the Lehman default in 2008 were much more effective in restraining risk premiums in banking markets than in the Treasury market and that, besides the shadow policy rate, the shadow ED rate is a useful indicator of the effect of default risk on the economy.