bluuebunny/crossref_metadata_2025_split huggingface dataset:
DIAGNÓSTICO, PREVENÇÃO E TRATAMENTO DAS ALERGIAS ALIMENTARES NA INFÂNCIA: UMA REVISÃO DE LITERATURA
Authors: Oliveira Linhares Marcelly Maria , De Araújo Neto Francisco Jazon , Jacome de Melo Gabriel Bruno , Diniz Gomes Pedro Natan , Ferreira Vital Pedro Italo , Rodrigues Mendes Pedrosa Pinto Ícaro , Bezerra Parente Beatriz , Mesquita Aguiar Ponte Mateus , Cunha de Oliveira Caroline , Sousa Lopes Samuel , Aissami Nadia , Cavalcante de Araújo Lia 
Published: October 2024

Introdução: As reações de hipersensibilidade alimentar são normalmente caracterizadas como respostas negativas provocadas pela ingestão de um alimento, podendo resultar em diversos sintomas ou, até mesmo, em óbito. Objetivo: Analisar e descrever, por meio de revisão de literatura, as principais formas de diagnóstico, prevenção e tratamento das alergias alimentares. Metodologia: O presente estudo trata-se de uma revisão de literatura sobre as alergias alimentares, com abordagem qualitativa e exploratória. Para esta pesquisa, foram utilizados estudos do PubMed e da Cochrane Library, sendo utilizada como ferramenta de busca: "Food Hypersensitivity" AND "Child". Ao final do processo de seleção, 10 artigos foram utilizados nesta pesquisa. Resultado: As alergias alimentares não apresentam um diagnóstico fácil, principalmente, devido às suas múltiplas manifestações clínicas e aos testes nem sempre conseguirem detectar os alérgenos. Para a prevenção, intervenções no período de introdução alimentar são necessárias, pois esse momento é marcado por seu impacto no desenvolvimento desse distúrbio. Enquanto isso, o tratamento das alergias alimentares depende da gravidade das reações e dos sintomas de cada paciente. Conclusão: Esta revisão de literatura promoveu uma análise acerca do diagnóstico, prevenção e tratamento das alergias alimentares durante a infância.
INCIDÊNCIA DE DISTÚRBIOS DO SONO E USO IRRACIONAL DE MEDICAMENTOS ENTRE DISCENTES DA ÁREA DA SAÚDE DE UMA UNIVERSIDADE NO PARANÁ
Authors: Andres Andressa Emanuelly , Maria Antônia Reichert Comin  , Ferreira Anderson Felipe , Mecabo Grazielle , Sackser Horvath Barbara 
Published: October 2024

Introdução: A cada dia mais o número de pessoas acometidas por distúrbios de sono cresce no Brasil e no mundo inteiro, e concomitantemente a isso, o número de fármacos utilizados no tratamento de tais patologias vem crescendo também. E dentre todos os grupos que podem ser acometidos por esses distúrbios, podemos destacar os acadêmicos de universidades, que foi o foco da respectiva pesquisa, pois a adaptação a um novo ambiente, a rotina corrida, e o estresse estão entre os fatores que favorecem a ocorrência de tais problemas (Carone, et al, 2020). Metodologia: O presente estudo analisou a incidência de distúrbios de sono, bem como seus interferentes e medicamentos utilizados para o tratamento, entre alunos dos cursos de saúde noturnos (Biomedicina, Psicologia, Estética, Odontologia e Enfermagem) da Universidade Paranaense – campus de Cascavel. Os resultados foram obtidos através de um estudo transversal e original, no qual se utilizou um questionário via Google Forms, referente a autoanálise a respeito da qualidade do sono e fatores que podem estar interferindo ou alterando a rotina. Resultados e Discussão: Participaram da pesquisa 455 discentes dos cinco cursos das áreas da saúde da Universidade Paranaense, e dentre eles, 330 (74,2%) relataram distúrbios relacionado a qualidade do sono, e 184 (41,3%) dos participantes afirmaram que utilizam ou já utilizaram em algum momento da vida medicamentos para tratar tais distúrbios. Os medicamentos mais utilizados pelos acadêmicos foram apontados os Benzodiazepínicos, anti-histamínicos e uso de alguns fitoterápicos, muitas vezes sem orientação e/ou prescrição médica. Considerações finais: Foi identificado uma preocupante prevalência de distúrbios de sono entre os alunos, a relação com seus com hábitos diários, e a falta de orientação quanto aos possíveis tratamentos para a melhora de tais doenças. Sugere-se que a rotina dentro de uma Universidade tem impacto na qualidade de vida dos alunos, com destaque para as noites de sono, podendo interferir no seu desempenho pessoal e acadêmico, favorecendo a automedicação e o uso irracional de medicamentos.
Palavras-chave: Benzodiazepínicos; Hipersonolência; Transtornos do Sono-Vigília, Automedicação.
Optimization Model of Tourism Android Application Based on Madura Local Wisdom as a Persuasive digitalization for Global Tourists
Authors: Sri Wahyuningsih  , Mohammad Arief Wahyudi  
Published: October 2024

Madura has natural, cultural, religious, and culinary attractions, this adds to the wealth of local wisdom of Madura to attract visitors from outside Madura. Bangkalan Regency itself has a lot of tourism, currently still under development by each village pokdarwis (kelompok sadar wisata) and assisted by the local tourism office, but this is not optimal. Such as tourism development through promotion and optimization has not been maximized. Looking at the background, the researcher wants to know, analyze, and dig deeply: 1) the Optimalization model of the application in Android destination-based traveler local wisdom as media persuasive for tourism global, 2) Why optimization of application in Android destination-based traveler local wisdom as digitalization persuasive for the important tourism global development. The subjects are village tourism managers, village heads, and tourism offices. The objects of the optimization in application android destination-based traveler local wisdom as persuasive digitalization for tourism global. Data collection methods through observation, in-depth interviews, documentation, audio-visual materials, and literature. The case study approach and the validity use data triangulation, methods, and member checks. The results of the research: 1) produced an optimization model of local wisdom-based tourist destination in android applications as persuasive media for global tourists, 2) importance of a tourism android application, to introduce potential Natural Beach Tourism, introduce potential artificial beach tourism, introduce superior religious tourism, introduce superior cultural tourism, introduce superior culinary tourism, increase the creative economy through local wisdom-based tourism, and provide information on village tourism that has the potential to become a leading tourism in Base.
Stealth Non-standard-model Confined Flare Eruptions: Sudden Reconnection Events in Ostensibly Inert Magnetic Arches from Sunspots
Authors: Moore Ronald L. , Tiwari Sanjiv K. , Panesar Navdeep K. , Aparna V. , Sterling Alphonse C. 
Published: October 2024

Abstract
We report seven examples of a long-ignored type of confined solar flare eruption that does not fit the standard model for confined flare eruptions. Because they are confined eruptions, do not fit the standard model, and unexpectedly erupt in ostensibly inert magnetic arches, we have named them stealth non-standard-model confined flare eruptions. Each of our flaring magnetic arches stems from a big sunspot. We tracked each eruption in full-cadence UV and EUV images from the Atmospheric Imaging Assembly of Solar Dynamics Observatory (SDO) in combination with magnetograms from SDO’s Helioseismic and Magnetic Imager. We present the onset and evolution of two eruptions in detail: one of six that each makes two side-by-side main flare loops, and one that makes two crossed main flare loops. For these two cases, we present cartoons of the proposed pre-eruption field configuration and how sudden reconnection makes the flare ribbons and flare loops. Each of the seven eruptions is consistent with being made by sudden reconnection at an interface between two internal field strands of the magnetic arch, where they cross at a small (10°–20°) angle. These stealth non-standard-model confined flare eruptions therefore plausibly support the idea of E. N. Parker for coronal heating in solar coronal magnetic loops by nanoflare bursts of reconnection at interfaces of internal field strands that cross at angles of 10°–20°.
Vélo et pandémie du Covid-19 : une structuration multiscalaire du réseau associatif en Île-de-France
Authors: Dusong Clément , Faure Emmanuelle , Demailly Kaduna-Eve , Bochaton Audrey 
Published: October 2024

Les travaux réalisés autour de la pandémie de Covid-19 présentent cette dernière comme une période de changement radical en matière de mobilité. La crise sanitaire a permis de renouveler les discours sur le vélo comme mode de déplacement quotidien et de franchir de nouvelles étapes en matière de politiques publiques (aides à la réparation de vélos, aménagements cyclables provisoires tels que les "coronapistes"). Cet article étudie la structuration du réseau associatif pro-vélo en Île-de-France, en analysant ses dynamiques spatiales et son évolution de 1970 à 2023. Dans quelle mesure la crise du Covid-19 a-t-elle constitué un accélérateur des processus en cours, ou bien un levier de changements plus radicaux ? L’article mobilise des données quantitatives (recensement d’associations) et qualitatives (récits d’histoires associatives, entretiens d’acteur.rice.s associatifs, de collectivités territoriales et institutions) issues de deux corpus : l’un constitué avant 2020, l’autre après cette date. Les principaux résultats montrent que le rôle de plaidoyer associatif a permis d’ancrer le vélo comme moyen de transport crédible en Île-de-France. Si ces discours pro-vélo sont bien antérieurs à la crise du Covid 19, celle-ci a permis au monde associatif de gagner en légitimité, en structuration et en capacité d’action. Ce renforcement s’est traduit différemment en fonction des échelles d’action.
Le bestiaire d’Adamek
Authors: Aron Paul 
Published: October 2024

André-Marcel Adamek est un romancier belge original, dont l’œuvre a rencontré un succès d’audience, mais qui demeure un peu négligé par la critique académique. On le classe généralement dans la tradition nationale des « fantastiqueurs ». L’article insiste sur l’importance des animaux dans son œuvre, et donc sur la possibilité de le lire comme un précurseur d’une nouvelle perception des relations entre humains et animaux.
Éditorial : Les mineurs non accompagnés en Europe : entre diversité des modèles d’accueil et harmonisation des mécanismes de contrôle
Authors: Senovilla Hernández Daniel 
Published: October 2024

En l’espace d’une décennie, l’émigration indépendante et spontanée des personnes mineures non accompagnées par des adultes responsables est devenue une manifestation migratoire consolidée au niveau mondial. Quand on considère l’Europe comme lieu de destination des enfants migrants isolés, les statistiques sont peu précises et ne sont pas toujours représentatives de la véritable ampleur du phénomène. Quoi qu’il en soit, les chiffres officiels ou connus sont inférieurs à 5 000 nouveaux cas par an, dans presque tous les États européens.
Dépôt des travaux de Master dans une archive HAL : la base DUMAS
Authors: Tardif Carole 
Published: October 2024

Dans l’élan général en faveur de l’Open Access, l’UFR de Sciences Humaines de Grenoble 2 a lancé le projet DUMAS (Dépôt Universitaire de Mémoires Après Soutenance - http://dumas.ccsd.cnrs.fr/), base d’archives ouvertes regroupant des travaux de niveau Master 1 et 2 validés par un jury.
Aspects législatifs de la situation des mineurs étrangers non accompagnés en Belgique
Authors: Van Zeebroeck Charlotte 
Published: October 2024

Chaque mois, on estime qu’environ 200 enfants étrangers arrivent en Belgique, seuls ou non accompagnés d’un adulte exerçant sur eux l’autorité parentale (parent ou tuteur). On les appelle couramment les MENA, pour « mineurs étrangers non accompagnés ». 70 % d’entre eux sont des garçons âgés de 15 à 18 ans. Ils viennent principalement d’Afrique (43 %), d’Europe hors Espace économique européen (30 %) et d’Asie (21 %)1.
La atención a los menores extranjeros no acompañados en el país Vasco: modelos de intervención y luces y sombras del sistema de acogida
Authors: Setién María Luisa , Barceló Fermín 
Published: October 2024

En los últimos nueve años, el sistema de acogida de menores del País Vasco ha atendido a cerca de 3.000 menoresinmigrantes no acompañados. Anteriormente, no existían extranjeros menores acogidos. Este cambio en los servicios de protección de menores ha generado la necesidad de hacer frente a los retos suscitados por la presencia de estos jóvenes inmigrantes, adaptándose a los nuevos problemas y desarrollando nuevos modelos de intervención para abordarlos.
CXCL12/CXCR4 Axis Promotes the Chemotaxis and Phagocytosis of B Cells through the PI3K-AKT Signaling Pathway in an Early Vertebrate
Authors: Gao Along , Lin Yuhua , Chai Yiwen , Han Jugan , Wu Liting , Ye Jianmin 
Published: October 2024

Abstract
Chemokines play crucial roles in the regulation of immune cell migration and development. The CXCL12/CXCR4 axis has been extensively studied in mammals, but its regulatory mechanism in teleost fish remains unclear. In this study, we used Nile tilapia (Oreochromis niloticus) as a teleost model to investigate the mediation of the CXCL12/CXCR4 axis in IgM+ B cells. Our findings demonstrate that the CXCL12/CXCR4 axis exhibits chemotactic activity on IgM+ B cells and promotes the phagocytosis of IgM+ B cells. Blocking CXCR4 severely impairs the chemotaxis and phagocytosis of IgM+ B cells in vitro and reduces the percentages and numbers of IgM+ B cells that migrate to peripheral blood after pathogen infection in vivo. This reduction in migration leads to a decrease in the inflammatory response, an increase in tissue bacterial load, and a decrease in survival rate. We also discovered that the evolutionarily conserved PI3K-AKT signaling pathway and Girdin are involved in the immune response during Streptococcus agalactiae infection. Inhibitors of the PI3K-AKT signaling pathway prevent the chemotaxis and phagocytosis of IgM+ B cells, impair the expression and phosphorylation levels of related proteins in vitro, and prevent IgM+ B cells chemotaxis into the peripheral blood after pathogen infection in vivo. Furthermore, CXCR4 blocking significantly downregulates the expression of AKT and Girdin. Overall, our study reveals the regulatory mechanism of the CXCL12/CXCR4 axis on IgM+ B cells via the PI3K-AKT signaling pathway in tilapia, suggesting that the functions of the CXCL12/CXCR4 axis in B cells may be conserved between mammals and teleost fish.
Assessment of Diaphragmatic Dysfunction in Mechanically Ventilated Patients with Ultrasonography
Authors: Sarkar Koushik , Chaudhury Maheswar , Bahinipati Pravakar , Das Somadatta 
Published: October 2024

Introduction:
The reliability of the diaphragm thickening fraction in predicting weaning failure in mechanically ventilated patients in the intensive care unit (ICU), as well as the relationship between the patients’ diaphragmatic inspiratory excursion and diaphragmatic thickness.

Materials and Methods:
Fifty mechanically ventilated patients participated in this hospital-based cross-sectional prospective study in a tertiary care teaching hospital. Patients who had been on a mechanical ventilator for at least 7 days and whose legal guardian was willing to provide consent were also included in the research. People with hemodynamic instability and those whose legal guardians were reluctant to comply were excluded.

Results:
Using diaphragmatic thickening fraction as a diagnostic criterion, the weaning failure group consisted of 24 patients, out of which we predicted diaphragmatic dysfunction (DD) in 19 patients. The weaning success group consisted of 26 patients, of which we predicted no DD in 21 patients. Weaning success or failure was predicted by diaphragmatic thickening fraction with a sensitivity of 79.16% and a specificity of 80.76%, diaphragm excursion with a sensitivity of 70.8% and an 80.7%, and diaphragmatic thickness with a sensitivity of 66.66% and a specificity of 73.91%, respectively.

Conclusion:
Diagnosing DD in mechanically ventilated, figuring out if extubation would be effective or not, monitoring respiratory effort, and assessing atrophy in ICU patients, ultrasonography may be an effective and accurate technique for mechanical ventilation patients, and it provides a convenient, noninvasive, affordable, and secure way to assess DD.
COVID-19 and Health-care Business Continuity in Africa: Perceptions of Risks and Vulnerabilities by Mid-level Management Staff in a Tertiary Care Hospital
Authors: Ndubuisi Mokogwu , Akoria Obehi Aituaje , Obaseki Darlington Ewaen , Gregrey Oko-oboh Agbonvihele 
Published: October 2024

Objectives:
The novel SARS-CoV-2 outbreak disrupted businesses globally and created fears in the general public and among health-care professionals. Almost universally, considerations about the coronavirus pandemic and its effects became priority in the daily operations of businesses, leaving hitherto pressing concerns in the back stage. Early in the pandemic, the management of University of Benin Teaching Hospital set up a Business Continuity Team which undertook an evaluation of the perceptions of mid-level hospital managers about their departments’ and units’ risks and vulnerabilities in the face of the ongoing pandemic.

Methods:
A modified International Labour Organization (ILO) risk profile self-assessment tool which focused on “people,” “processes,” “profits,” and “partnerships” was used to assess mid-level managers’ perceptions of their respective departments’ and units’ risks and vulnerabilities, consequent on the COVID-19 pandemic. Responses were obtained from heads of departments and units using an online survey. Final scores were divided into terciles (three equal groups) in respect of perceived risks and adverse outcomes of the COVID-19 pandemic. Scores in the lower tercile were grouped as low risk/vulnerability, the middle group of scores as medium risk/vulnerability, and scores in the upper tercile as high risk/vulnerability.

Results:
Responses were obtained from 35 (49.3%) of the 71 clinical and nonclinical departments and units in the hospital. Fifteen of these (42.9%) were clinical. Nineteen (54.2%) departments were assessed to be at high risk/vulnerability, 9 (47.4%) of which were clinical. Twelve (34.3%) departments were assessed to be at medium risk/vulnerability – 4 (33.3%) of them, clinical. No department was assessed to be at low risk. The highest risk ratings were in the domains of “profits” and “partnerships:” 54 (84.4%) mid-level managers assessed their departments and units to be at high risk of the negative impacts of the coronavirus pandemic with respect to “profits” and 51 (79.7%) with respect to “partnerships.”

Conclusion:
Mid-level managers in clinical and nonclinical departments and units assessed their departments and units to be at medium and high risk of the negative impacts of the COVID-19 pandemic, using the ILO’s modified tool. Our findings enabled the management of the hospital and the Business Continuity Team to address the specific areas of concerns that were highlighted, develop contingency plans, and frame risk communication during the pandemic, with a view to fostering increased sense of safety in the workforce. This approach to risk assessment is repeatable, and we recommended it to other hospitals in Africa.
Health Facility Capacity and Health-care Worker Knowledge, Attitudes, and Practices of Hepatitis B Vaccine Birth-dose and Maternal Tetanus-Diphtheria Vaccine Administration in Nigeria: A Baseline Assessment
Authors: Uba Belinda V. , Mohammed Yahaya , Nwokoro Ugochukwu Uzoechina , Fadahunsi Rhoda , Adewole Adefisoye , Ugbenyo Gideon , Simple Edwin , Wisdom Margeret Osas , Waziri Ndadilnasiya E. , Michael Charles A. , Okeke Lilian Akudo , Kanu Florence , Ikwe Hadley , Sandhu Hardeep S. , Asekun Adeyelu , Tohme Rania A. , Freeland Catherine , Minta Anna , Bashir Sulaiman Saidu , Isa Abdullahi , Vasumu James J. , Bahuli Abubakar U. , Ugwu George O. , Obi Emmanuel I. , Ismail Binta Aduke , Okposen Bassey Bassey , Bolu Omotayo O. , Shuaib Faisal 
Published: October 2024

Background:
Hepatitis B virus (HBV) and neonatal tetanus infections remain endemic in Nigeria despite the availability of safe, effective vaccines. We aimed to determine health facilities’ capacity for hepatitis B vaccine birth dose (HepB-BD) and maternal tetanus-diphtheria (Td) vaccination and to assess knowledge, attitudes, and practices of HepB-BD and maternal Td vaccine administration among health facility staff in Nigeria.

Materials and Methods:
This was a cross-sectional study assessing public primary and secondary health facilities in Adamawa and Enugu States. A multistage sampling approach was used to select 40 facilities and 79 health-care workers (HCWs) from each state. A structured facility assessment tool and standardized questionnaire evaluated facility characteristics and HCW knowledge, attitudes, and practices related to HepB-BD and maternal Td vaccination. Frequencies and proportions were reported as descriptive statistics.

Results:
The survey of 80 facilities revealed that 73.8% implemented HepB-BD and maternal Td vaccination policies. HepB-BD was administered within 24 h of birth at 61.3% of facilities and at all times at 57.5%. However, administration seldom occurred in labor and delivery (35%) or maternity wards (16.3%). Nearly half of the facilities (46.3%) had HCWs believing there were contraindications to HepB-BD vaccination. Among 158 HCWs, 26.5% believed tetanus could be transmitted through unprotected sex, prevented by vaccination at birth (46.1%), or by avoiding sharing food and utensils. 65% of HCWs knew HBV infection had the worst outcome for newborns.

Conclusions:
The limited implementation of national policies on HepB-BD and maternal Td vaccination, coupled with knowledge gaps among HCWs, pose significant challenges to timely vaccination, necessitating interventions to address these gaps.
Clinical and Radiological Parameters Affecting the Yield of Routine Electroencephalography in Various Indications
Authors: Shahid Rizwana , Zafar Azra , Nazish Saima , Alameri Sarah Ali , Shariff Erum , Alshamrani Foziah , Aljaafari Danah , Soltan Nehad Mahmoud , Alkhamis Fahd A. , Albakr Aishah Ibrahim , Alabdali Majed , Saqqur Maher 
Published: October 2024

Objectives:
To highlight the significance of various clinical and radiological parameters in association with specific electroencephalographic (EEG) patterns in order to prioritize EEG referrals.

Method:
This retrospective, cross-sectional study was conducted in the neurology department of King Fahad University Hospital, Alkhobar, and involved a review and analysis of EEG and medical records pertaining to 604 patients referred for routine EEG. The data were analyzed using SPSS version 22. An association between various parameters and EEG yield was established.

Results:
Factors associated with the yield of abnormal EEG patterns were diverse, like generalized tonic-clonic seizures (GTCs) (P =.05), status epilepticus (SE) (P =.05), altered level of consciousness (ALC) (P =.00), abnormal movement (P =.00), cardiac arrest (P =.00), prior history of epilepsy (P =.04), chronic renal disease (CRD) (P =.03), abnormal neurological exam (P =.00), and cortical lesions on brain imaging (P =.00). Among the abnormal EEG patterns, epileptiform activity (EA) in EEG was associated with focal seizures (P =.03), GTCs (P =.00), falls (P =.05), cardiac arrest (P =.00), a history of epilepsy (P =.00), and hypoxic ischemic injury (P =.03). Encephalopathy in EEG was also associated with focal sz (P =.02), GTCs (P =.00), SE (P =.01), ALC (P =.00), cardiac arrest (P =.00), history of stroke (P =.01), and epilepsy (P =.00).

Conclusion:
Among the studied parameters, patient level of consciousness, neurological exam findings, and neuroimaging findings, with some discrepancies, were found to be the most consistent in predicting the EEG yield. The study demonstrated the value of a proper neurological exam and careful selection of patients to gain the optimum benefit from the routine EEG.