bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cuidado familiar a crianças com adoecimentos crônicos raros
Authors: Androlage Juliana Soares , Souza Ítala Paris de , Barsaglini Reni Aparecida , Bellato Roseney , Dias Milena Fernandez , Lessa Rosângela Souza , Bezerra Maria Simone Mendes 
Published: September 2024

Objetivo: Descrever as características sobre o cuidado familiar da criança com adoecimento crônico raro, disponíveis nas bases de dados na área da saúde. Métodos: revisão integrativa da literatura realizada nas bases de dados Web of Science, Medical Literature Analysis and Retrievel System Online, Cumulative Index to Nursing and Allied, Literatura Latino-americana e do Caribe em Ciências da Saúde, Scientific Electronic Library Online, Banco de Dados em Enfermagem e Índice Bibliográfico Español en Ciencias de la Salud. Constituiu-se amostra de 57 estudos sobre o tema. Resultados: Constatou-se alto índice de publicações em 2019, predominância de produçao internacional e método qualitativo. Categorizou-se a produção em quatro eixos temáticos: Desafios no processo de viver e cuidar; Mudanças, impactos e necessidades de suporte/cuidados; Ferramentas para auxiliar as famílias e/ou profissionais no cuidado e Recebimento do Diagnóstico. Considerações finais: Embora a importância do cuidado familiar a crianças com adoecimentos crônicos raros seja evidente, a produção indica uma desadequação entre a demanda das famílias e o apoio recebido, resultando em sobrecarga. Recomenda-se reflexões para que práticas de cuidados em que a interface política/cuidado familiar/doenças raras estejam interconectadas, abrandando, a sobrecarga enfrentada pelas famílias no cuidado solitário.
Pavel Petrovich Shibanov as a Supplier of Books for the Libraries of the Imperial Family (Late 19th — Early 20th Century)
Authors: Sokolov Alexander S. 
Published: September 2024

On the basis of letters from the collection No. 342 of the Manuscripts Department of the Russian State Library (RSL) the co-operation of the famous Russian antiquarian book dealer of the late 19th — early 20th century P.P. Shibanov with the members of the House of Romanov in the field of formation of their personal libraries is studied. The study was carried out with the aim of obtaining reliable information about the editions offered to complete the personal libraries of the Imperial House. On the basis of previously unexplored sources the assortment of P.P. Shibanov’s booksellers, presented for purchase to the members of the Imperial Family, is revealed. The letters from the Shibanov collection of the RSL were received by the bookseller from high-ranking officials of the courts of the grand dukes and grand duchesses, and in some cases directly from members of the dynasty. The material gives an idea of the spheres of intellectual predilections of the Romanovs, of their interest in rare and ancient editions, among which were books of the 17th—18th centuries. The prices for books indicated in the letters are of no small importance. Among the information about the booksellers’ assortment offered to the Romanovs we should mention the books that for one reason or another did not interest the members of the dynasty during the preliminary acquaintance and were returned to the bookseller.In the course of the research, the drafts of P.P. Shibanov’s letters to the Moscow Governor-General, Grand Duke Sergei Alexandrovich, were revealed, and the exchange of telegrams with the Pushkin enthusiast, Prince Oleg Konstantinovich of Imperial Blood, was analyzed.Most of the letters were received from the court offices of the Grand Dukes Nikolai Mikhailovich (a famous historian), Konstantin Konstantinovich and Pyotr Nikolayevich (through the court office of the latter the sending of books to his wife, Grand Duchess Militsa Nikolaevna, for familiarization was discussed).The letters we have identified cover mainly the late 1890s — early 1900s; the latest are a telegram from Prince Oleg Konstantinovich of Imperial Blood, received by P.P. Shibanov in 1913, and a letter from the court office of Grand Duke Konstantin Konstantinovich in 1915.The studied letters reveal the book assortment offered by P.P. Shibanov to the members of the Imperial Family and the book preferences of the Romanovs, but do not indicate whether these books were purchased by them.
“Rumyantsev Readings — 2024”: N.P. Rumyantsev’s Heritage and Topical Issues of Development of Modern Librarianship
Authors: Ivanova Elena A. 
Published: September 2024

On 23—25 April 2024, the Russian State Library (RSL) hosted the annual International Research and Practical Conference “Rumyantsev Readings” (organizers: Ministry of Culture of the Russian Federation, RSL, the Library Assembly of Eurasia). The topics raised at the conference invariably attract a large number of specialists from different regions of Russia and other countries with their versatility and relevance. In 2024, representatives of the Russian Federation, the Republic of Belarus, the Republic of Azerbaijan, the Republic of Armenia, the Republic of Kazakhstan, the Kyrgyz Republic, the Republic of Tajikistan, and the Republic of Uzbekistan took part in it. Our country was represented by specialists from many cities and regions. 294 people took part in the event in person, 1,697 connections were recorded during the broadcasting of the sessions.The conference topics covered a wide range of issues on the theory and practice of library science, bibliography and book studies. Among its main directions: history of libraries and other scientific and cultural institutions, as well as pages of life and activity of people connected with them; disclosure of book depositories’ funds; research of collections and individual copies of manuscript and printed monuments; multifaceted activities of modern libraries. One of the main goals of the conference is to expand intercultural interaction and co-operation between cultural, educational and scientific institutions. Within the framework of the “Rumyantsev Readings” the work of sections, both traditional for many years, and timed to the dates and events of 2024, was organized. Special attention was paid to the personality and heritage of the creator of the Rumyantsev Museum N.P. Rumyantsev (1754—1826), whose 270th anniversary is being celebrated in 2024. Other key topics of the conference were: “Scientific and methodological activities of libraries”, “Collectors, curators, researchers: the history of cultural institutions in the faces”, “The selfless people of the past and modern volunteer movement in the life of libraries”, “Book monuments in the library collections: creation, existence, storage and use”, “Library collections in the digital environment”, “Staffing makes the difference: young researchers in the modern library”.The programme of the event included, in addition to the plenary session, ten sections and two round tables. By the beginning of the conference a collection of materials in three parts was prepared and published by the publishing house of the RSL “Pashkov Dom”, it included 168 articles by 180 authors.“Rumyantsev Readings” have been held for more than four decades and continue to be a popular research and practical event among library professionals and representatives of other educational, scientific and cultural institutions, contributing to the development of scientific research and the introduction of new practices.
Об экспоненциальном росте числа конечных асимметричных гамильтоновых графов
Authors: Perminov E.A. , Kaplenko A.V. 
Published: September 2024

Combinatorial analysis of various algebraic systems and their properties is an urgent problem of modern algebra. In a number of works, the growth function of algebraic systems has been studied, which, for a given natural n, indicates the number of n-element finite algebraic systems of a given type. In many works, the actual problem of studying various transformations of algebraic systems has also been investigated. In particular, it was investigated how "rich" or, conversely, "poor" the considered algebraic systems are with transformations of one kind or another. The paper studies asymmetric Hamiltonian graphs with only an identical automorphism. The article proves that the exponential growth function of asymmetric Hamiltonian graphs is.
Комбинаторный анализ различных алгебраических систем и их свойств является актуальной проблемой современной алгебры. В ряде работ изучалась функция роста алгебраических систем, которая для заданного натурального n указывает число n-элементных конечных алгебраических систем заданного вида. Во многих работах исследовалась также актуальная проблема изучения различных преобразований алгебраических систем. В частности, исследовалось, насколько «богаты» или, наоборот, «бедны» рассматриваемые алгебраические системы преобразованиями того или иного вида. В статье изучаются асимметричные гамильтоновы графы, обладающие только тождественным автоморфизмом. В статье доказано, что является экспоненциальной функция роста асимметричных гамильтоновых графов.
Concerns and challenges faced by parents of children with autism spectrum disorder during the coronavirus pandemic in Indian scenario
Authors: Jayalakshmi Nivethitha Gopalakrishnan , Sankar Amudhu , Sunil Priyanka 
Published: September 2024

IntroductionThe coronavirus pandemic has prevented children with autism spectrum disorder (ASD) from procuring clinical services which have led to changes in lifestyle and daily routines. Also, the parents of children with ASD were concerned regarding maintaining routines and introducing new experiences to their children during the pandemic. This is a cross-sectional study that explored the concerns and challenges faced by parents of children with ASD during the coronavirus pandemic.AimThe main objectives of this study were to profile the communication difficulties and environmental changes adopted by parents of children with ASD who did not have proper access to healthcare/rehab facilities during the pandemic in Indian scenario.Material and methodsIn total, 51 parents of children with ASD in the age range of 3 to 10 years participated in this study. They were asked to fill in a questionnaire (Google form) that had 20 close ended questions on their children's prelinguistic skills, communication behaviors, behavioral aspects, and emotional variations before and during the pandemic.Results and discussionThe results revealed that children with ASD exhibited significant emotional and behavioral upheaval due to interruptions in routine connected to COVID-19. Depending on the severity of the disorder, children had difficulty in several tasks such as comprehension of simple commands and expression of daily needs. Also, the parents of children with ASD were concerned about maintaining routines and introducing new experiences to their children during the pandemic.ConclusionsIndividuals with ASD are a significant population who may require special assistance during the pandemic and future public health crises.
Batu Urethtra Anterior pada Pasien Pediatri
Authors: Fauzan Ahmad , Harahap Amir Ahnaf Falih 
Published: September 2024

Batu saluran kemih (BSK) didefinisikan sebagai pembentukan batu di saluran kemih yang meliputi batu ginjal, ureter, buli, dan uretra. Batu uretra biasanya dianggap sebagai penyakit pasien dewasa, namun peningkatan prevalensi penyakit ini juga diamati pada populasi anak-anak. Hal ini terkait dengan perkembangan peradaban, perubahan dalam pola makan dan gaya hidup. Di beberapa negara di dunia berkisar antara 1-20%. Laki-laki lebih sering terjadi dibandingkan perempuan yaitu 3:1 dengan puncak insiden terjadi pada usia 40-50 tahun. Pasien laki-laki 5 tahun datang ke IGD RSU Cut Meutia dengan keluhan buang air kecil tertahan sejak 2 hari SMRS dan nyeri pada bagian perut bawah, nyeri menetap tanpa ada penjalaran nyeri dilakukan sistosmi dan dirujuk ke RSUD Zainoel Abidin untuk tindakan ureteroscopy. Inspeksi : Distensi (+) full blast (+) MUE : Normal, Fimosis (+) Aukulasi : Peristaltik usus normal. Penatalaksanaan Non farmakologi (Tirah baring, kateter) Farmakologi : (IVFD RL 10 tpm, inj. Ceftriaxone 750 mg /12jam, inj. Paracetamol 200mg /12jam, inj. Ondancetron 1amp/12jam, Tindakan operatif sistostomi dan ureteroscopy. Berdasarkan hasil anamesis dan pemeriksaan fisik pada pasien dapat ditegakkan Batu Uretra Anterior Pars Pendular.
Risk Profiles in Geriatric COVID-19 Patients: Vaccination Impacts on Hospitalization and Survival During the Omicron Wave
Authors: SOLAK GRASSIE Semiha , ÜNALAN ALTINTOP Tuğçe 
Published: September 2024

Introduction: The Omicron variant causes less severe disease than other variants. Although most patients experienced a mild course, an increase in hospitalizations and intensive care unit follow-ups was observed. The course of the disease was more severe, especially in the geriatric population. This study investigated the factors leading to hospitalization, intensive care needs, and mortality in older patients. Materials and method: Between October 2022 and March 2023, COVID-19 patients aged > 60 years were included in the study. Patients’ demographic features, underlying diseases, initial symptoms, vaccinations, treatment, secondary bacterial infections, and COVID-19 history were investigated. Mortality rates at the hospital and after discharge were investigated. Results: Adding three or more mRNA vaccines to the vaccination schedule was associated with a reduced risk of hospitalization and intensive care unit admission. Patients with repeated vaccine doses had no mortality or intensive care unit follow-up, whereas unvaccinated patients had 13.3% mortality and 46.6% intensive care unit follow-up. 80-year-olds and older had higher mortality. The mortality rate of patients admitted to the hospital with a deteriorating general condition was considerably higher (28.8%) than that of other patients (5.4%). Patients with a COVID-19 history had fewer intensive care unit visits (10.25%). The mortality rate among hospitalized patients who did not receive molnupiravir was higher (40%) than that of those who received treatment (14%). Conclusion: Repeated vaccine doses, heterologus, and full-dose mRNA vaccination reduced mortality and hospitalization rates. Patients aged ≥80 have a higher risk of mortality. Molnupravir treatment significantly decreased the mortality rate. Keywords: COVID-19; SARS-CoV-2; Vaccination; Mortality.
Pathomorphological Changes of the Placenta in Antenatal Asphyxia of the Fetus Associated with the Coronavirus Disease (COVID-19) in Pregnant Women
Authors: Savchuk T.V. 
Published: September 2024

Сoronavirus disease (COVID 19) in a pregnant woman remains a risk factor for perinatal losses despite the barrier function of the placenta. This prompted us to do some research.
Objective — to determine the pathomorphological changes of the placenta and fetus during antenatal asphyxia in the acute period of COVID-19 in a pregnant woman.
Materials and methods. We studied placentas and fetuses in case of antenatal asphyxia (n = 16) in the acute period of the COVID-19 in a pregnant woman, confirmed by a positive PCR test (determination of SARS-CoV-2 RNA). The duration of the post-COVID interval (time from the diagnosis of COVID-19 to delivery) was 1—3 weeks.
Results and discussion. Intrauterine death of the fetus occurred at different gestational period: from 26 to 38 weeks (median 33). At the same time, the woman fell ill with COVID-19 between 18 and 35 weeks of gestation (median 31). Hemorrhages in the right atrium and auricle of the heart were observed in fetuses — 93.8 % (95 % CI: 75.4—100); dark blood clots in the chambers of the heart; hemorrhages under the periosteum of the bones of the skull, stasis in the veins of the brain — 81.3 % (95 % CI: 57.1—96.7), hemorrhages in the scrotum, spermatic cord — 6.3 % (95 % CI: 0.0—24.6) and kidney hemorrhages — 62.5 % (95 % CI: 36.2—85.4). When examined macroscopically, the placenta was characterized by a flabby or dense consistency; diffuse hemorrhages or local blood clots in numerous cysts; areas of abruption, thrombosis of umbilical cord vessels. Microscopic examination of the placenta revealed chorioamnionitis — 81.3 % (95 % CI: 57.1—96.7 %), intervillositis — 93.8 % (95 % CI: 75.4—100), acute villitis — 56.3 % (95 % CI: 30.2—80.6). Basal deciduitis was detected in all observations in 100 % (95 % CI: 88.8—100). Disorders of blood circulation were found in the placentas: stasis, thrombosis, hemorrhages; and necrosis of the arteriole endothelium — 100 % (95 % CI: 88.8—100 %).
Conclusions. COVID-19 in a pregnant woman from 18 to 35 weeks of gestation (median 31) is a risk factor for perinatal losses. No significant differences were found between the severity of the course of COVID-19 in the mother and the morphological changes of the placenta. Pathognomonic changes in the fetus with COVID-19 in the mother in the acute period: «porphyry lung», hemorrhages in the right atrium, under the periosteum of the bones of the skull, spermatic cord, kidneys, blood clots in the chambers of the heart. The cause of antenatal death of the fetus in the acute period of COVID-19 in a pregnant woman is acute placental insufficiency associated with disorder of placental-fetal blood circulation, due to manifestations of the exudative phase of inflammation: placentitis (focal chorioamnionitis, acute villitis, intervilositis, basal deciduitis) and disorder of blood rheology, which was manifested by thrombosis, hemorrhages in the intervillous space, detachment of the placenta.
Comparación entre los sistemas de clasificación etiológica del accidente cerebrovascular en pacientes que asisten al Sanatorio Allende Córdoba
Authors: Facundo M , Tarducci ME , Martín JJ 
Published: September 2024

La identificación de la causa subyacente del accidente cerebro vascular (ACV) es importante para orientar las decisiones de tratamiento y pronóstico en los pacientes. La identificación de la etiología se realiza en forma más frecuente por medio de la clasificación TOAST, otro sistema es CCS, basado en una aplicación web, que reconoce la etiología del ACV en un amplio rango de causas. Objetivo: Comparar la eficiencia diagnostica de los sistemas de clasificación TOAST (Trial of Org 10172 in Acute Stroke Registry) y el Sistema de Clasificación Causativo (CCS) en pacientes con ACV que asisten al Sanatorio Allende.Los sistemas de clasificación TOAST y CCS se aplicaron a 100 pacientes que asistieron al Servicio de Neurología del Sanatorio Allende, y a partir de los datos de las historias clínicas en forma retrospectiva, se describió las frecuencias de los subtipos en pacientes con ACV y se analizó la eficiencia diagnostica de ambos tipos de clasificación. Para la comparación, las etiologías determinadas se definieron con subtipos evidentes y probables, según el esquema CCS y se analizaron mediante el Índice Kappa.Según CCS 3 (3%) de los pacientes son de etiología No determinada desconocida, 10 (10%) son de etiología indeterminado desconocido / otras causas criptogénica, 2(2%) son no determinada no conocida/ embolica criptogenica y 5 (5%) son de etiología no determinado no conocido/ evaluación incompleta totalizando 20 (20%); Según TOAST 39 (39%) de los pacientes son de etiología indeterminada. Hubo un acuerdo diagnostico excelente entre los subtipos asignados por TOAST y el CCS (?=0.81). Para los principales subtipos individuales la concordancia también fue excelente: aterosclerosis de grandes vasos (k = 0.898), oclusión de arterias pequeñas (k = 0.98), cardio-embolia (k= 0.95), Otras causas (k=0.88). Se observó acuerdo moderado para la categoría indeterminada (k =0.564). Se observa concordancia diagnostica casi perfecta entre los dos sistemas de clasificación, concluimos que, el sistema CCS es más eficiente para determinar la etiología del ACV en comparación al TOAST, debido a que logra disminuir el número de casos de etiología indeterminada, por otra parte al ser un algoritmo web, aumenta la confiabilidad inter evaluador.
Estudio comparativo entre atorvastatina y metformina sobre la actividad mitocondrial del complejo III hepático en síndrome metabólico experimental
Authors: Castillo TA , Scribano MP , Tarán M , Balceda A , Mukdsi J , Blencio S , Blencio S , Moya M , Baez MC 
Published: September 2024

Diversas investigaciones relacionan la inflamación y el estrés oxidativo (EO) como inductores de lesión hepática en patologías con riesgo de enfermedad cardiovascular, como el Síndrome Metabólico (SM). La producción de superóxido mitocondrial es un importante mediador de la injuria oxidativa celular, así mismo, el complejo III podría estar implicado como mediador en la generación y como blanco alternativo de óxido nítrico en la regulación de la respiración mitocondrial. Por lo tanto, la disfunción del complejo III generaría una sobreproducción de especies reactivas de oxígeno y de nitrógeno, perpetuando las lesiones generadas por EO en SM. Atorvastatina (Ator.), por sus efectos pleiotrópicos antioxidantes, y Metformina (Met.), por su acción sobre la cadena respiratoria, preservarían la funcionalidad del complejo III, manteniendo la homeostasis celular. OBJETIVO: Estudiar en un modelo experimental de SM la acción farmacológica de atorvastatina y metformina sobre actividad enzimática del complejo III.Se utilizaron 40 ratas Wistar, machos, divididas en 5 grupos (n=8 cada uno): (A) Control, (B) SM, (C) SM+Ator., (D) SM+Met., (E) SM+Ator.+Met. El SM fue inducido a través de fructosa 10% diluida en agua de bebida durante 6 semanas; se administró 0,035 mg/día/rata de atorvastatina (equivalente 10 mg en humanos) y 1,78 mg/día/rata de metformina (equivalente 500 mg en humanos), durante 45 días, via oral mediante sonda esofágica. Los procedimientos empleados en los animales fueron aprobados por el CICUAL. La actividad del complejo III (?M de ubiquinona/ min.mg de proteína) se cuantificó en pellet mitocondrial de hígado por espectrofotometría. Análisis estadístico: test de LSD Fisher, p<0.05.El análisis de la actividad enzimática del complejo III en el grupo (B) evidenció un incremento significativo (0,03±0,002) comparado con (A)(0,02±0,0029) (p<0,02). Los grupos (C) (0,01±0,0049), (E) (0,01±0,0033) y (D) (0,02±0,0034) mostraron una disminución significativa de la actividad respecto a (B), (C y E vs. B) (p<0,01) (D vs. B) (p<0,02).La administración de atorvastatina permitió una regresión del estado prooxidativo evidenciado por una restauración de actividad del complejo III, similar respuesta se observó en el grupo con metformina en cuanto a la actividad enzimática, ambos presentando diferencias significativas al grupo con SM. Por último, al administrar ambos fármacos combinados la actividad de dicho complejo se restituyó de igual manera, demostrando una acción beneficiosa de estos dos compuestos sobre la función mitocondrial.