bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incorporating Evidence-Based Practice Learning Activities Throughout Family Nurse Practitioner Clinical Practicum Courses
Authors: Lee Monica , Bobek Heidi , Casler Kelly 
Published: September 2024

Background:
Evidence-based practice (EBP) is crucial to high-quality health care, yet nurse practitioner graduates report low levels of confidence in their EBP abilities. This may be because of limited incorporation of EBP learning opportunities outside of foundational course-work.

Method:
Family nurse practitioner (FNP) program faculty incorporated EBP learning activities across the three-semester clinical year curriculum, and the activities scaffolded in complexity. Initial activities included appraisal and application of clinical practice guidelines to patient case scenarios. Later, students used the seven steps of EBP to present frequently asked patient questions and EBP clinical challenges in their clinical rotations to their peers.

Results:
This innovative way to thread EBP across the clinical year allowed faculty to continue to evaluate and guide students toward EBP competency.

Conclusion:

The integration of EBP learning activities across the clinical year is a feasible strategy to further expand FNP student competency in EBP.

[
J Nurs Educ
. 2024;63(X):XXX–XXX.]
Taxonomic notes, new species, and new records of Neotropical Cerambycidae (Coleoptera)
Authors: Santos-Silva Antonio , Pérez-Flores Oscar , Botero Juan Pablo 
Published: September 2024

Abstract
Haplidus glabricollis Chemsak and Linsley, 1964 is synonymised with Limernaea ochracea (Fisher, 1927) (Coleoptera: Cerambycidae: Cerambycinae: Oemini). Adetus scissicauda (Bates, 1874) (Coleoptera: Cerambycidae: Lamiinae: Apomecynini) is reinstated, and Adetus alboapicalis Breuning, 1943 is proposed as a junior synonym. Adetus salvadorensis Franz, 1954 (Coleoptera: Cerambycidae: Laminae: Apomecynini) is redescribed and recorded from Oaxaca, Mexico. Plistonax antonkozlovi Santos-Silva et al., 2020 (Coleoptera: Cerambycidae: Lamiinae: Acanthoderini) and Hesychotypa danilevskyi Nearns and Nascimento, 2019 (Coleoptera: Cerambycidae: Lamiinae: Onciderini) are recorded for the first time for the province of Bocas del Toro, Panama. Dorcasta borealis Breuning, 1940 (Coleoptera: Cerambycidae: Lamiinae: Apomecynini) is newly recorded from Mexico (Yucatán). The type locality of Eupogonius longipilis Bates, 1880 (Coleoptera: Cerambycidae: Lamiinae: Desmiphorini) is corroborated and new state record from Chiapas, Mexico, is reported. Eupogonius vittipennis Bates, 1885 is recorded for Campeche, Mexico. Trichastylopsis skillmaninew species (Coleoptera: Cerambycidae: Laminae: Acanthocinini) is described from Jalisco and Michoacán, Mexico.
Association between coagulation indicators and menorrhagia among women in Kenya
Authors: Marabi Phidelis M. , Musyoki Stanslaus K. , Monari Fred , Kosiyo Paul M. , Ouma Collins 
Published: September 2024

Background: Despite the significant burden of menorrhagia (bleeding 80 mL every menstrual cycle) among women in Western Kenya, it remains unknown whether coagulation disorders are an important underlying cause of this condition in the region.Objective: This study assessed differences in coagulation profiles, associations between menorrhagia and coagulation profiles and compared morphological features of platelets among women attending Bungoma County Referral Hospital in Kenya.Methods: A comparative cross-sectional study of women with and without menorrhagia, aged 18–45 years, was performed between December 2022 and September 2023. Sociodemographic factors, prothrombin time (PT), activated partial thromboplastin time, thrombin time, fibrinogen, international normalised ratio (INR), and platelet count were compared between groups, and associations with menorrhagia were assessed. Prothrombin time and INR levels above normal references were deemed increased.Results: A total of 428 (214 per group) women were included. Family history of bleeding disorders (p 0.0001) was more frequent in menorrhagic than in non-menorrhagic women. Additionally, menorrhagic women had high PT (p 0.0001) and high INR (p 0.0001) levels. Menorrhagia was significantly associated with an increased PT (odds ratio = 2.129, 95% confidence interval = 1.658–2.734; p 0.0001) and increased INR (odds ratio = 7.479, 95% confidence interval = 3.094–18.080; p 0.0001).Conclusion: In this population in Western Kenya, menorrhagia was associated with a family history of bleeding disorders, increased PT, and increased INR. Routine assessment of the coagulation profile and family history of bleeding disorders is crucial for diagnosing and managing menorrhagia.What this study adds: Our findings suggest that menorrhagic and non-menorrhagic women differ in terms of PT and INR, which may be predictive of menorrhagia.
Two hundred years of indigenous literature in South Africa
Authors: Odendaal Andre 
Published: September 2024

As far back as the 1860s, Tiyo Soga wrote about the need to collect and write stories about African pasts so that they could be deposited in newspaper archives, which could become a ‘big corn pit’ of knowledge for the nation. His biographer noted that he was sometimes up after midnight in a hut, ‘notebook in hand’, learning from ‘wrinkled countrymen of his own’ about the past. Izibongo zoogxa, a compilation of some of the writings of Samuel Edward Krune (S.E.K.) Mqhayi, one of the most important figures in the history of Xhosa literature, is part of the multigenerational harvest that Soga envisaged, and there are two special reasons to celebrate its publication.
Reterritorialisation of the transformative power of self-care activities: Students’ wellness
Authors: Mthembu Thuli G. , Dube Tibuyile L. , Milojevic Tijana , Ndaramu Beverly P. , Nyangaza Philasande , Qolo Siyamtanda O. , Steenkamp Candice 
Published: September 2024

Students including health sciences at universities that appear to subscribe to neoliberal logic are at risk for social injustices and inequalities, anxiety, depression, academic demands and unethical activities. There has been little discussion about students’ self-care and well-being in and beyond the neoliberal universities. This article explored the transformative power of self-care activities on the wellness and learning of health sciences students at a university in the Western Cape, South Africa. A qualitative exploratory-descriptive research approach was conducted with 10 health sciences students purposively recruited from a South African university. Data were collected through semi-structured interviews audio-recorded, transcribed verbatim and analysed thematically. Three themes identified from the analysis were: students’ understanding of self-care, engagement in self-care activities and the transformative power of self-care activities. The key barriers to engagement in self-care activities were academic demands and unsafe environments; however, the students had to make time and effort.Contribution: This article makes several noteworthy contributions to how self-care horizontal and complicated conversations can be infused into health sciences education and work-integrated learning contexts to heal and transform the wounds of neoliberal logic at universities. Additionally, we propound the applicability of ubuntu currere (ubuntu curriculum) and wellness as liberating frameworks that can be used for reterritorialisation and reconceptualisation of self-care and well-being to cultivate health sciences students’ professional and personal development.
Neo-Liberalism’s Shadows: Modern slavery in South African Higher Education
Authors: Steynberg Lizl , Grundling Jan P. , Venter Marius 
Published: September 2024

Neoliberal ideology globally prioritises competition and productivity over staff well-being in higher education, leading to exploitative practices and heightened stress among academic faculty, culminating in what can be termed modern academic slavery. This study investigates the contemporary impact of neoliberalism on South African universities, focussing on governance, funding and academic freedom, and how these factors contribute to deteriorating conditions for academic staff and toxic work environments. This research examines academic experiences in a South African urban higher education institution (HEI) utilizing a single-case study approach. It examines their context within institutional and societal trends. Using a single-case ideographic approach in a South African HEI, the study utilises detailed documentation, incident analysis and literature review to understand academic enslavement within the chosen HEI, contextualising the academic’s experiences within these broader institutional and societal trends. The findings reveal four key themes: moral disengagement, corporate malfeasance, exploitative labour practices, and labour coercion, illustrating the widespread exploitation of academic staff. The study advocates for urgent interventions to ensure respectful treatment, foster ethical work environments, and address disparities between administrators and faculty. It calls for autonomy, ethical leadership and a culture of inquiry in HEIs to combat modern academic slavery while acknowledging the need for further action and exploration.Contribution: This study underscores the current impact of neoliberalism on higher education in South Africa, exposing challenges for academic staff and advocating systemic reforms. It emphasises the necessity for future investigations into institutional accountability and strategies to enhance staff well-being in HEIs.
Serum tumor markers (carcinoembryonic antigen, carbohydrate antigen 19-9, carbohydrate antigen 72-4, carbohydrate antigen 24-2, ferritin) and gastric cancer prognosis correlation
Authors: Zhu Jie-Wen , Gong Ling-Zhen , Wang Qian-Wen 
Published: September 2024

BACKGROUND
Gastric cancer is a kind of malignant tumor which is prevalent all over the world. Although some progress has been made in the treatment of gastric cancer, its prognosis is still not optimistic, so it is of great significance to find reliable prognostic indicators to guide the treatment and management of patients with gastric cancer.
AIM
To explore the relationship between serum levels of five biomarkers [carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, CA72-4, CA24-2, and ferritin] and prognosis in patients with gastric cancer.
METHODS
This study included 200 patients with gastric adenocarcinoma, and conducted an in-depth analysis of their baseline characteristics, relationship between tumor markers and staging, and prognosis. The study found that CA19-9 has a significant correlation with tumor stage, the average levels of CA24-2, CEA, CA72-4 and ferritin were slightly increased disregarding the stage of tumor. Survival analysis showed that increases in CEA, CA19-9, CA24-2, and ferritin were all associated with shortened overall survival of patients. Further multivariate analysis revealed that elevated serum CA72-4 levels were an independent adverse prognostic factor.
RESULTS
This study reveals that there is a significant correlation between the expression levels of serum tumor markers CEA, CA19-9, CA72-4, CA24-2 and ferritin in patients with gastric cancer and prognosis, and can be used as important indicators for prognostic evaluation of gastric cancer. In particular, markers that appear abnormally elevated initially may help identify gastric cancer patients with poor prognosis.
CONCLUSION
Serum CEA and CA19-9 play an important role in the prognosis assessment of gastric cancer, and are effective tools to guide clinical practice and optimize individualized treatment strategies for gastric cancer patients.
Impact of dexmedetomidine-assisted anesthesia in elderly patients undergoing radical resection of colon cancer
Authors: Tian Xiao-Peng , Bu Hui-Min , Ma Hong-Yan , Zhao Min 
Published: September 2024

BACKGROUND
Radical resection of colon cancer under general anesthesia is one of the main treatment methods for this malignancy. However, due to the physiological characteristics of elderly patients, the safety of perioperative anesthesia needs special attention. As an α2-adrenergic receptor agonist, dexmedetomidine (Dex) has attracted much attention from anesthesiologists due to its stabilizing effect on heart rate and blood pressure, inhibitory effect on inflammation, and sedative and analgesic effects. Its application in general anesthesia may have a positive impact on the quality of anesthesia and postoperative recovery in elderly patients undergoing radical resection of colon cancer.
AIM
To investigate the anesthetic effects of Dex during radical surgery for colon cancer under general anesthesia in elderly patients.
METHODS
A total of 165 colon cancer patients who underwent radical surgery for colon cancer under general anesthesia at Qingdao University Affiliated Haici Hospital, Qingdao, China were recruited and divided into two groups: A and B. In group A, Dex was administered 30 min before surgery, while group B received an equivalent amount of normal saline. The hemodynamic changes, pulmonary compliance, airway pressure, inflammatory factors, confusion assessment method scores, Ramsay Sedation-Agitation Scale scores, and cellular immune function indicators were compared between the two groups.
RESULTS
Group A showed less intraoperative hemodynamic fluctuations, better pulmonary compliance, and lower airway resistance compared with group B. Twelve hours after the surgery, the serum levels of TLR-2, TLR-4, IL-6, and TNF-α in group A were significantly lower than those of group B (P < 0.05). After extubation, the Ramsay Sedation-Agitation Scale score of group A patients was significantly higher than that of group B patients, indicating a higher level of sedation. The incidence of delirium was significantly lower in group A than in group B (P < 0.05).
CONCLUSION
The use of Dex as an adjunct to general anesthesia for radical surgery in elderly patients with colon cancer results in better effectiveness of anesthesia.
Advancing gastrointestinal stromal tumor management: The role of imagomics features in precision risk assessment
Authors: Pan Gui-Hai , Zhou Fei , Chen Wu-Biao , Pan Ze-Jun 
Published: September 2024

BACKGROUND
Gastrointestinal stromal tumors (GISTs) vary widely in prognosis, and traditional pathological assessments often lack precision in risk stratification. Advanced imaging techniques, especially magnetic resonance imaging (MRI), offer potential improvements. This study investigates how MRI imagomics can enhance risk assessment and support personalized treatment for GIST patients.
AIM
To assess the effectiveness of MRI imagomics in improving GIST risk stratification, addressing the limitations of traditional pathological assessments.
METHODS
Analyzed clinical and MRI data from 132 GIST patients, categorizing them by tumor specifics and dividing into risk groups. Employed dimension reduction for optimal imagomics feature selection from diffusion-weighted imaging (DWI), T1-weighted imaging (T1WI), and contrast enhanced T1WI with fat saturation (CE-T1WI) fat suppress (fs) sequences.
RESULTS
Age, lesion diameter, and mitotic figures significantly correlated with GIST risk, with DWI sequence features like sphericity and regional entropy showing high predictive accuracy. The combined T1WI and CE-T1WI fs model had the best predictive efficacy. In the test group, the DWI sequence model demonstrated an area under the curve (AUC) value of 0.960 with a sensitivity of 80.0% and a specificity of 100.0%. On the other hand, the combined performance of the T1WI and CE-T1WI fs models in the test group was the most robust, exhibiting an AUC value of 0.834, a sensitivity of 70.4%, and a specificity of 85.2%.
CONCLUSION
MRI imagomics, particularly DWI and combined T1WI/CE-T1WI fs models, significantly enhance GIST risk stratification, supporting precise preoperative patient assessment and personalized treatment plans. The clinical implications are profound, enabling more accurate surgical strategy formulation and optimized treatment selection, thereby improving patient outcomes. Future research should focus on multicenter studies to validate these findings, integrate advanced imaging technologies like PET/MRI, and incorporate genetic factors to achieve a more comprehensive risk assessment.
Pain and immune function in patients undergoing gastric cancer surgery following stellate ganglion block with total intravenous anesthesia
Authors: Wu Zhen , Cai Hong-Qin , Wang Chun-Feng , Yu Xiang-Yuan , Wang Jie-Qiong 
Published: September 2024

BACKGROUND
Stellate ganglion block is a commonly used sympathetic nerve block technique that restores the balance of the sympathetic and vagal nervous systems of the body and inhibits sympathetic nerve activity.
AIM
To analyze the effect of a stellate ganglion block combined with total diploma intravenous anesthesia on postoperative pain and immune function in patients undergoing laparoscopic radical gastric cancer (GC) surgery to provide a reference basis for the formulation of anesthesia protocols for radical GC surgery.
METHODS
This study included 112 patients who underwent laparoscopic radical surgery for GC between January 2022 and March 2024. There was no restriction on sex. The patient grouping method used was a digital random table method, and the number of cases in each group was 56. The control group was administered total intravenous anesthesia, and the observation group compounded the stellate ganglion block according to the total intravenous anesthesia protocol. Postoperative hemodynamics, pain levels, and immune indices were compared between the groups.
RESULTS
The heart rate and mean arterial pressure in the observation group after intubation were lower than those in the control group (P < 0.05). Pain levels were compared between the two groups at 2 hours, 12 hours, 24 hours, and 48 hours after surgery (P > 0.05). The number of CD3+, CD4+, and CD4+/CD8+ cells at the end of surgery was higher in the observation group than in the control group, and the number of CD8+ cells was lower in the observation group than in the control group (P < 0.05). There were no significant differences between the two groups in terms of propofol dosage, awakening time, extubation time, or postoperative adverse reactions (P > 0.05).
CONCLUSION
The application of a stellate ganglion block combined with total intravenous anesthesia had no significant effect on postoperative pain levels in patients undergoing laparoscopic radical GC surgery. However, it can safely reduce the effect of surgery on the immune function of patients and is worth applying in clinical practice.
Bowel preparation experiences and needs before follow-up colonoscopy in older adult postoperative colorectal cancer patients: A qualitative study
Authors: He Bin , Xin Yi , Li Rui , Lin Fu-Cai , Zhang Guang-Ming , Zhu Hai-Jing 
Published: September 2024

BACKGROUND
The bowel preparation process prior to colonoscopy determines the quality of the bowel preparation, which in turn affects the quality of the colonoscopy. Colonoscopy is an essential procedure for postoperative follow-up monitoring of colorectal cancer (CRC) patients. Previous studies have shown that advanced age and a history of colorectal resection are both risk factors for inadequate bowel preparation. However, little attention has been paid to the bowel preparation experiences and needs of predominantly older adult postoperative CRC patients.
AIM
To explore the experiences and needs of older adult postoperative CRC patients during bowel preparation for follow-up colonoscopy.
METHODS
Fifteen older adult postoperative CRC patients who underwent follow-up colonoscopy at a tertiary hospital in Shanghai were selected using purposive sampling from August 2023 to November 2023. The phenomenological method in qualitative research was employed to construct an interview outline and conduct semi-structured interviews with the patients. Colaizzi's seven-step analysis was utilized to organize, code, categorize, summarize, and verify the interview data.
RESULTS
The results of this study were summarized into four themes and eight sub-themes: (1) Inadequate knowledge about bowel preparation; (2) Decreased physiological comfort during bowel preparation (gastrointestinal discomfort and sleep deprivation caused by bowel cleansing agents, and hunger caused by dietary restrictions; (3) Psychological changes during different stages of bowel preparation (pre-preparation: Fear and resistance due to previous experiences; during preparation: Irritation and helplessness caused by taking bowel cleansing agents, and post-preparation: Anxiety and worry while waiting for the colonoscopy); and (4) Needs related to bowel preparation (detailed instructions from healthcare professionals; more ideal bowel cleansing agents; and shortened waiting times for colonoscopy).
CONCLUSION
Older adult postoperative CRC patients' knowledge of bowel preparation is not adequate, and they may encounter numerous difficulties and challenges during the process. Healthcare professionals should place great emphasis on providing instruction for their bowel preparation.
Endoscopic clipping of gastrojejunostomy leakage following Whipple procedure: A case report
Authors: Muhammedoğlu Bahtiyar , Ay Oguzhan Fatih 
Published: September 2024

BACKGROUND
Currently, perioperative complications of classic Whipple surgery occur at a rate of approximately 40%. Common complications include delayed gastric emptying, pancreatic fistula, and bile leakage, whereas gastrojejunostomy (GJ) leakage is rare.
CASE SUMMARY
This case report will assess the management of a GJ leak in a 71-year-old male patient following the Whipple procedure. After surgery, the patient was transferred to the clinic after four days of intensive care, where vacuum therapy was used to handle a developing subcutaneous collection. The patient, who had bile in the drains and incision during follow-up, underwent endoscopic examination on the 21st day after the operation. An opening of approximately 4 mm was observed in the GJ anastomosis during endoscopy. Five titanium clips were used to close the openings. The drainage of bile decreased to less than 50 mL on the first day after the procedure, and the patient's oral intake was opened.
CONCLUSION
Current literature reports a GJ leakage rate of 0. 54% following Whipple surgery, with clinical findings lasting on average between 4-34 days. Surgery was the main form of therapy for this case, with a success rate of 84%, and percutaneous drainage was also utilized as a treatment option. This case report is the first to document endoscopic treatment of GJ leaks following the classic Whipple procedure.
Left inferior phrenic arterial malformation mimicking gastric varices: A case report and review of literature
Authors: Wang Han , Tan Yi-Qing , Han Ping , Xu An-Hui , Mu Han-Lin , Zhu Zhe , Ma Li , Liu Mei , Xie Hua-Ping 
Published: September 2024

BACKGROUND
Gastric submucosal arterial dilation resulting from splenic artery occlusion represents an exceedingly rare etiology of acute upper gastrointestinal bleeding (UGIB). Although endoscopy is a widely utilized diagnostic and therapeutic modality for gastrointestinal bleeding, it has limitations in detecting arterial abnormalities.
CASE SUMMARY
This report presents a rare case of massive UGIB in a 57-year-old male with a tortuous left inferior phrenic artery accompanied by splenic artery occlusion. “Gastric varices” was identified during the patient's endoscopy one year before hemorrhage. Despite initial hemostasis by endoscopic clipping, the patient experienced massive rebleeding after one month, requiring intervention with transcatheter arterial embolization (TAE) to achieve hemostasis.
CONCLUSION
This is the first case to report UGIB due to a tortuous left inferior phrenic artery. This case highlights the limitations of endoscopy in identifying arterial abnormalities and emphasizes the potential of TAE as a viable alternative for the management of arterial bleeding in the gastrointestinal tract.