bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined antegrade and retrograde dilation (CARD) for management of complete esophageal obstruction: Multicenter case series
Authors: Hayat Umar , Khan Yakub I , Deivert Duane , Obuch Joshua , Altaf Athar , Boger John , Kamal Faisal , Diehl David L 
Published: October 2024

Abstract
Background and study aims Complete esophageal obstruction (CEO) is a rare complication of radiation therapy for esophageal or head and neck cancers and can be challenging to manage endoscopically. A rendezvous approach by combined anterograde and retrograde endoscopic dilation (CARD) can be used to re-establish luminal integrity in such cases. Our study aimed to review our experience with patients with CEOs managed by CARD.
Patients and methods Six patients who had CARD for CEO were reviewed. The primary outcomes were immediate technical and clinical success of CARD. Secondary outcomes were adverse events (AEs) associated with the procedure and continued dependency on the percutaneous endoscopic gastrostomy (PEG)-or jejunostomy tube.
Results The mean age was 59 years (range 38–83). Five patients had CEO secondary to neoadjuvant chemoradiotherapy for esophageal cancer, and one patient had complete obstruction secondary to neck trauma. CARD was technically successful in five patients (86%). Two patients had AEs. One had pneumomediastinum requiring no intervention, while the other had bilateral pneumothorax requiring chest tube placement. The median follow-up duration of repeated dilations to maintain liminal patency was 20 months. Four patients had improvement in dysphagia, tolerating oral intake, and mouth secretions after the procedure, with a mean functional oral intake scale (FOIS) score > 3 and an overall success rate of 83%.
Conclusions The CARD approach to re-establish esophageal luminal patency in CEO is a safer alternative to high-risk blind antegrade dilation or an invasive surgical approach. It is usually technically feasible with improved swallowing ability in most patients.
Enhancing Referrals to the Supplemental Nutrition Assistance Program through Clinical Integration of a Standards-Based Decision Support System
Authors: Oliveira Eliel , Hautala Matti , Henry JaWanna , Lakshminarayanan Vidya , Abrol Vishal , Granado Linda , Shah Shashank , Khurshid Anjum 
Published: October 2024

Abstract
Background The Supplemental Nutrition Assistance Program (SNAP) is one of the most successful national programs to reduce poverty and improve health outcomes, but millions of Americans who qualify still do not have access to SNAP, and limited data are available to determine how referrals to the program can be completed successfully.
Objectives We aimed to design and develop a standards-based digital care coordination platform to support closed-loop social services referrals between patients and social and health care providers and demonstrate the feasibility to screen, diagnose, plan, and complete interventions with selected patients in real settings.
Methods We partnered with community members to design the platform through Community Engagement Studios and with a Federally Qualified Health Center, Local Mental Health Authority, and Food Bank to determine the features and workflow requirements of the platform design. We customized currently available systems to use Fast Healthcare Interoperability Resources (FHIR) Application Programming Interfaces (APIs) that could exchange information in real time across providers and participants.
Results The platform was successfully demonstrated through a pilot where patients were recruited in clinical settings and referred to a Food Bank that provided SNAP application assistance to study participants. We translated the requirements of the platform to national standards and required workflows of providers and patients. Study participants were notified electronically of the specific steps to follow to complete their SNAP applications while receiving support from specialists from the Food Bank.
Conclusion The pilot demonstrated the feasibility of collecting granular social service referral information that can be used to better address gaps in social care. The pilot also highlighted the importance of further coordination on the usage and harmonization of needs assessment nationally and that current digital systems are still not ready to fully utilize national Social Determinants of Health data standards.
Impact of Pharmacologic Patent Ductus Arteriosus Treatment on Acute Respiratory and Oxygenation Metrics in Very Low Birth Weight Infants
Authors: Weigner Mara K. , Kausch Sherry L. , Fairchild Karen D. , Sullivan Brynne A. 
Published: October 2024

Objective Hypoxemia and respiratory compromise occur in very low birth weight (VLBW, <1,500 g) infants and may be associated with shunting across patent ductus arteriosus (PDA). The impact of pharmacologic PDA treatment on acute hypoxemia and respiratory metrics is unclear. This study aimed to determine whether pharmacologic PDA treatment is associated with acute improvement in hypoxemia and respiratory metrics in VLBW infants.
Study Design At a single center (2012–2022), all VLBW infants with echocardiographic evidence of PDA and without exclusions were classified as having received or not received pharmacologic PDA treatment (PDA-T and PDA-NT). Mean daily fraction of inspired oxygen (FIO2) and Respiratory Acuity Score (RAS, PMID 30374050) were compared at baseline (day 0) and 3 days after the start of treatment. For PDA-T infants with archived 0.5 Hz (every 2-second) oxygen saturation (SpO2) data, mean daily SpO2 and the percentage of time with severe hypoxemia (SpO2 <80%) were compared before and after treatment. Severe hypoxemia was further analyzed after stratification by clinical variables (sex, medication, gestational age, and postnatal age).
Results We analyzed 125 VLBW infants with PDA, of whom 66 received pharmacologic PDA treatment. We analyzed a subgroup of 43 PDA-T infants with every 2-second SpO2 data available. PDA-T infants had higher baseline FiO2 and RAS and lower SpO2 than PDA-NT infants (p < 0.05). Compared to baseline, RAS decreased from a median of 258 (interquartile range [IQR]: 171, 348) to 254 (IQR: 174, 419), 3 days after the start of treatment (p = 0.012), but median FiO2 increased from 37% (IQR: 28, 46) to 40% (IQR: 29, 52; p = 0.008). SpO2 and the percent time with severe hypoxemia were unchanged.
Conclusion In this 10-year, retrospective, single-center analysis, pharmacologic PDA treatment in VLBW infants was not associated with a major improvement in acute measures of oxygenation or level of respiratory support.
Key Points
DXA: New Concepts and Tools Beyond Bone Mineral Density
Authors: Pizza Irene Carmen , Bongiorno Alessia , Pedullà Martina , Albano Domenico , Sconfienza Luca Maria , Messina Carmelo 
Published: October 2024

AbstractSince its introduction in 1987, dual-energy X-ray absorptiometry (DXA) has revolutionized bone assessment, becoming the gold standard for measuring bone mineral density (BMD). Its low radiation exposure and high accuracy have made it indispensable in diagnosing osteoporosis, aligning with World Health Organization criteria. However, DXA evolution extends beyond BMD measurement, with emerging tools like the Trabecular Bone Score (TBS) and the DXA-based Bone Strain Index (BSI). TBS provides insights into trabecular bone architecture, enhancing the prediction of fracture risk. Despite limitations like body mass index correlation, TBS aids in evaluating patients with conditions such as diabetes and glucocorticoid exposure. BSI, introduced in 2019, evaluates bone strength using finite element analysis, complementing BMD and TBS by assessing bone fatigue.Advancements in DXA-based tools extend to Hip Structural Analysis and three-dimensional DXA software, offering valuable insights into hip fracture risk. Moreover, DXA serves beyond bone assessment, aiding in abdominal aortic calcification assessment, enhancing cardiovascular risk stratification. In summary, the expanding capabilities of DXA promise comprehensive skeletal and cardiovascular health evaluation, contributing significantly to clinical management and prevention strategies.
Trabecular Bone Score to Enhance Fracture Risk Prediction and Treatment Strategies in Osteoporosis
Authors: Gatineau Guillaume , Hans Didier , Hind Karen 
Published: October 2024

AbstractThe Trabecular Bone Score (TBS), a gray-level textural assessment derived from dual-energy X-ray absorptiometry images, serves as a validated index of trabecular bone microarchitecture. Over the past decade, significant evidence has highlighted the usefulness of TBS in primary and secondary osteoporosis, leading to its integration with the Fracture Risk Assessment Tool (FRAX) and bone mineral density (BMD) T-score adjustments. This review explores the role of TBS in fracture prediction, treatment initiation, and monitoring. Studies confirm that TBS enhances fracture risk prediction in both primary and secondary osteoporosis when combined with BMD and clinical risk factors. Evidence also suggests that including TBS alongside BMD and FRAX offers significant potential for treatment stratification, considering the overall skeletal profile, such as bone mass, bone quality, and clinical risk factors. Consequently, TBS has become a standard part of clinical care worldwide. Future enhancements hope to adjust for soft tissue thickness, broadening the applicability of TBS across diverse body types and pediatric populations.
Top 10 Clinical Pearls in Inherited Neuropathies
Authors: Patel Ruchee , Mukherjee-Clavin Bipasha 
Published: October 2024

AbstractThe inherited neuropathies are a clinically and genetically heterogeneous collection of neuropathies that neurologists, particularly neuromuscular specialists, must be familiar with. They include Charcot–Marie–Tooth disease, which is common yet currently lacks targeted treatment, and hATTRV polyneuropathy, which is rare but has disease-modifying gene therapies. With a focus on emerging new genes and treatments, this article offers a recent update on clinical diagnosis and management of inherited neuropathies.
Routine activities and consumer fraud victimization: findings from a social survey in Chiba Prefecture, Japan
Authors: Suzuki Ai 
Published: October 2024

Abstract
Recently, Japan has been grappling with various forms of consumer fraud. Consumer fraud victimization causes not only monetary losses but also nonmonetary costs such as emotional stress and psychological trauma. Therefore, it is necessary to investigate the factors associated with the risk of consumer fraud victimization in order to identify vulnerable groups and implement suitable prevention measures. Consequently, this study aims to analyze the sociodemographic and routine activity factors associated with consumer fraud victimization risk in Japan. Drawing on data from a social survey of residents in Chiba Prefecture, Japan, this study employs a series of logistic regression models. This study demonstrates that while using social networking services is unrelated to respondents’ likelihood of experiencing consumer fraud victimization, the frequency of contacting individuals whom respondents have only met online was statistically linked to increased consumer fraud risk. Additionally, only 10.7 to 31.9% of respondents were aware of the available support services for victims of consumer fraud and related issues. This study proposes that social networking providers could aid in preventing consumer fraud by displaying warning messages when users send messages, alerting them to possible threats.
Stimulated Brillouin scattering in silica optical nanofibers
Authors: Zerbib Maxime , Deroh Moise , Sylvestre Thibaut , Huy Kien Phan , Beugnot Jean-Charles 
Published: October 2024

Stimulated Brillouin scattering offers a broad range of applications, including lasers, sensors, and microwave photonics, most of which require strong Brillouin gain within a narrow bandwidth. Here, we experimentally report the first measurement of stimulated Brillouin scattering in silica optical nanofibers from both hybrid and surface acoustic waves. Using a pump–probe technique in the radio frequency domain, we measured a Brillouin gain as high as 15 m−1 W−1 and linewidth to 16 MHz for the L03 hybrid acoustic mode near 9 GHz using a 990-nm diameter nanofiber. This gain is 65 times larger than the highest gain obtained in standard single-mode fibers. In addition, we report a Brillouin gain of up to 5 m−1 W−1 from surface acoustic waves around 5 GHz. We further demonstrate a nanofiber-based Brillouin laser with a threshold of 350 mW. Our results create opportunities for advanced Brillouin-based applications utilizing optical nanofibers.
Helium roaming in excess electrons in C60F60 as dynamic quasi-Matryoshka dolls
Authors: Liu Yang , Feng Shanshan , Bu Yuxiang 
Published: October 2024

Multi-guest clathrates exhibit lots of functional characteristics owing to their unique structures, which herald beautiful application prospects, but their fundamental information is still scarce. Herein, we explore a type of (helium, excess electrons/EEs)–C60F60 co-clathrates with quasi-Matryoshka-doll structures using ab initio molecular dynamics simulation and reveal the EEs-entangled He roaming dynamics in C60F60 and its effect on the characteristics of clathrates. Perfluorination ensures that C60F60 possesses an extremely electropositive interior cavity. Its unique confinement effect can stabilize He as an extremely inert entity by noticeably enlarging the 1s–2s orbital gap and can also trap 1–2 EEs in its s-type interior orbital with extremely large binding energies. Co-inclusion of He and EEs in C60F60 exhibits inter-repulsive He⋯EEs entangling dynamics featuring quasi-Matryoshka-doll structures (He@EEs@C60F60). In this structure, EEs screen the attraction of cage-shell Cδ+ to He 1s2 electrons, thus inhibiting their stabilization and orbital expansion, while He conversely decreases the stability of EEs and redshifts their transition absorption. He can roam in the cavity, but its trajectory is impacted by EEs serving as a medium, and thus, the structures exhibit anormal dynamic variation of internuclear He⋯C spin coupling JHeC, which is manipulated by the EEs-entangled He roaming dynamics. JHeC and JHeC′ present opposite distance dependences for the colinearly aligned C⋅⋅⋅He⋅⋅⊗⋅⋅⋅⋅⋅C′ (⊗, the cage center). This work provides insights into the Matryoshka-doll structured He@EEs@C60F60 with He–EEs entangling dynamics and its modulation on EEs absorption and reveals the dynamic role of EEs in manipulating He-roaming and JHeC coupling properties for promising applications.
Construction of Ag-modified ZnO/g-C3N4 heterostructure for enhanced photocatalysis performance
Authors: Liu Shanshan , Cheng Shaoli , Zheng Jiale , Liu Junhui , Huang Mingju 
Published: October 2024

ZnO/g-C3N4 heterojunction modified with Ag nanoparticles (ZnO/CN/Ag) was synthesized by depositing ZnO nanorods/Ag nanoparticles onto g-C3N4 nanosheets. Under xenon lamp irradiation, 99% of Rhodamine B (RhB) was degraded by ZnO/CN/Ag-5% composite within 30 min, which was much higher than the degradation efficiency of ZnO and ZnO/CN. The synergistic effect of g-C3N4 and ZnO, along with the localized surface plasmon resonance effect of Ag NPs, contributes to the improvement of photocatalytic performance. Ag nanoparticle provides another charge transfer path from g-C3N4 to ZnO, which speeds up the separation of electron–hole pairs. Meanwhile, the catalyst had good stability and recyclability. Finite-difference time-domain method and the density functional theory were used to obtain the charge transfer process. The photodegradation process has been studied in depth.
High radiation efficiency and tunable resonance planar double-turn spiral antenna for manipulation of nitrogen-vacancy centers
Authors: Gao Ang , Zhao Liye , Yan Ruqiang , Wang Yuhai 
Published: October 2024

Nitrogen-vacancy (NV) centers in diamond are promising quantum sensors, where microwave antennas play a crucial role in manipulating the spin states accurately. Conventional microwave antennas often struggle to balance radiation efficiency and bandwidth. To address this challenge, we design a planar double-turn spiral antenna (PDTSA), based on the ring microstrip antenna (RMA). PDTSA demonstrates an ∼4.5-fold increase in radiation efficiency compared to RMA. In addition, the PDTSA allows linear tunability of the resonance frequency up to 500 MHz by adjusting the spiral input length. This feature addresses the limitations of a narrow working frequency range, which are typically caused by the narrowband in high-radiation-efficiency antennas. The experimental results show that at an absolute input power of 1 W, the PDTSA increases the Rabi frequency from 1.72 to 8.06 MHz compared to the RMA. This enhancement accelerates quantum state manipulation and reduces phase accumulation errors. These characteristics make PDTSA suitable for applications in quantum sensing and precision measurements using NV centers.
QCManyBody: A flexible implementation of the many-body expansion
Authors: Burns Lori A. , Sherrill C. David , Pritchard Benjamin P. 
Published: October 2024

While the many-body expansion (MBE) and counterpoise treatments are commonly used to mitigate the high scaling of accurate ab initio methods, researchers may need to piece together tools and scripts if their primary chosen software does not support targeted features. To further modular software in quantum chemistry, the arbitrary-order, multiple-model-chemistry, counterpoise-enabled MBE implementation from Psi4 has been extracted into an independent, lightweight, and open-source Python module, QCManyBody, with new schema underpinning, application programming interface, and software integrations. The package caters to direct users by facilitating single-point and geometry optimization MBE calculations backed by popular quantum chemistry codes through the QCEngine runner and by defining a schema for requesting and reporting many-body computations. It also serves developers and integrators by providing minimal, composable, and extensible interfaces. The design and flexibility of QCManyBody are demonstrated via integrations with geomeTRIC, OptKing, Psi4, QCEngine, and the QCArchive project.
Exogenous γ-aminobutyric acid (GABA) enhances rye (Secale cereale) seedling resistance to combined freeze-thaw and cadmium stress
Authors: Wang Huixin , Bao Guozhang , Tian Lingzhi , Chen Simeng , Xu Yanan , Li Guomei , Zhao Hongwei 
Published: October 2024

Freeze-thaw is a common stress at high altitudes in northern China. There is a risk of cadmium (Cd) contamination in the region. γ-aminobutyric acid (GABA) is a natural product that regulates plant growth. Rye (Secale cereale) was used as research material to investigate the physiological effects of exogenous GABA on rye seedlings under the single and combined stresses of freeze-thaw and cadmium. The results showed that the combined stress severely inhibited shoot length, root length, fresh weight, and dry weight, increased malondialdehyde and hydrogen peroxide contents, and significantly decreased superoxide dismutase (SOD) activity. Foliar application of 5 mM GABA alleviated the negative effects of stress on seedling growth, increased soluble protein content, and reduced malondialdehyde and hydrogen peroxide contents. Exogenous GABA application also enhanced the activities of SOD and peroxidase (POD). Additionally, the presence of exogenous GABA activated the GABA metabolic process and encouraged the accumulation of phytochelatins, glutathione, and non-protein thiol. These results indicate that exogenous GABA can effectively improve the resistance of rye seedlings to freeze-thaw and Cd by regulating the antioxidant enzyme system and enhancing its own detoxification mechanism, and they provide a basis for future applications of exogenous GABA, which is beneficial for ecological protection.
Fermionized Dual Vortex Theory for Magnetized Kagomé Spin Liquid
Authors: Pan 潘 Si-Yu 斯语 , Chen 陈 Gang v. 钢 
Published: October 2024

Abstract
Inspired by the recent quantum oscillation measurement on the kagomé lattice antiferromagnet in finite magnetic fields, we raise the question about the physical contents of the emergent fermions and the gauge fields if the U(1) spin liquid is relevant for the finite-field kagomé lattice antiferromagnet. Clearly, the magnetic field is non-perturbative in this regime, and the finite-field state has no direct relation with the U(1) Dirac spin liquid proposal at zero field. We here consider the fermionized dual vortex liquid state as one possible candidate theory to understand the magnetized kagomé spin liquid. Within the dual vortex theory, the Sz
magnetization is the emergent U(1) gauge flux, and the fermionized dual vortex is the emergent fermion. The magnetic field polarizes the spin component that modulates the U(1) gauge flux for the fermionized vortices and generates the quantum oscillation. Within the mean-field theory, we discuss the gauge field correlation, the vortex–antivortex continuum and the vortex thermal Hall effect.
Statistical Properties and Cosmological Applications of Fast Radio Bursts
Authors: Wu 吴 Qin 沁 , Wang 王 Fa-Yin 发印 
Published: October 2024

Abstract
Fast radio burst (FRB) is a type of extragalactic radio signal characterized by millisecond duration, extremely high brightness temperature, and large dispersion measure. It remains a mystery in the universe. Advancements in instrumentation have led to the discovery of 816 FRB sources and 7622 bursts from 67 repeating FRBs (https://blinkverse.alkaidos.cn/). This field is undergoing rapid development, rapidly advancing our understanding of the physics of FRBs as new observational data accumulates. The accumulation of data has also promoted exploration of our universe. In this review, we summarize the statistical analysis and cosmological applications using large samples of FRBs, including the energy functions, the waiting time distributions of repeating FRBs, probe of missing baryons and circumgalactic medium in the universe, measurements of cosmological parameters, exploration of the epoch of re-ionization history, and research of the gravitational lensing of FRBs.
Topology optimization of extreme mechanical metamaterials considering the anisotropy of additive manufactured parts
Authors: Zheng Ran , Yi Bing , Tao Yong , Peng Xiang 
Published: October 2024

Abstract
Additive manufacturing (AM) has the advantage of fabricating complex geometries designed by topology optimization. However, the layer-by-layer stacking of AM causes the anisotropic property of the manufactured parts, which is rarely considered in the topology optimization of metamaterials. Hence, this paper presents a new method for the topology optimization of metamaterials with anisotropic properties. First, the elastic moduli in different directions of anisotropic materials are introduced into the solid isotropic material with penalization interpolation function. Then, the effective elastic properties of anisotropic metamaterials are evaluated using the energy-based homogenization method, and the formulation of the topology optimization of anisotropic metamaterials is constructed, and it is iteratively solved by the method of moving asymptotes algorithm. Finally, several two-dimensional and three-dimensional numerical examples and a set of mechanical experiment are conducted to demonstrate the effectiveness of the proposed method.