bluuebunny/crossref_metadata_2025_split huggingface dataset:
Un masque humain à Hyria de Naxos, nouveau témoignage de contacts chypriotes
Authors: Simantoni-Bournia Eva 
Published: November 2016

Eva SIMANTONI-BOURNIA
A Human Mask from Hyria on Naxos: New Evidence of Cypriot Contacts
p. 119-132
Nine sherds of a terracotta mask representing a male bearded figure of nearly life size, dating to the end of the 8th - beginning of the 7th c. BC, were discovered in 1994 in the sanctuary of Hyria on Naxos. The Naxian mask owes its importance to the rarity of this type of objects, above all in the high period. The terracotta masks from the Sanctuary of Orthia at Sparta, the best known and most striking in the Greek world, are nearly all later and most of them related to a different stylistic tradition. The Cypriot Geometric I terracotta masks brought to light in the sanctuaries of Kition and Salamis in Cyprus are the nearest parallels to the Hyria example.
It is suggested that the idealised bearded Hyria mask was worn during some sort of pageant (δρώμενον) by the person playing the role of the husband of the goddess of fertility who was venerated along with Dionysus in the great Naxian sanctuary and is identified with Ariadne. The representation, frequent in the cult of Dionysus, of a sort of ritual union in the cult practices at Hyria is probable. The Cypriot contacts, confirmed by our mask, support the parallel, which we have suggested before on the basis of the finds from the sanctuary and from literary evidence, between the Naxian Ariadne and the great Cypriotoriental goddess.
L'accueil officiel des souverains et des princes à Athènes à l'époque hellénistique
Authors: Perrin-Saminadayar Eric 
Published: November 2016

Eric Perrin-Saminadayar
Η επίσημη υποδοχή των ηγεμόνων και των πριγκίπων στην Αθήνα κατά την ελληνιστική περίοδο
σ. 354-375
Αφηγούμενος την επίσημη επίσκεψη του Αττάλου Α' στην Αθήνα το 200 π.Χ., ο Πολύβιος τονίζει στην εξαιρετική υποδοχή που επιφύλαξε στο βασιλέα ολόκληρη η πόλη. Περιγράφει ένα πρωτόκολλο απαντήσεως, βασιζόμενο σε ένα πρότυπο που συναντάμε σε άλλες περιοχές για άλλους βασιλείς. Στην Αθήνα όμως, παρόλο που υπήρχε πρωτόκολλο που όριζε την υποδοχή των σημαντικών προσώπων, δεν εφαρμοζόταν μόνο προς τους βασιλείς σε επίσημη επίσκεψη: κατά την ελληνιστική περίοδο οι εκπρόσωποι των «φίλων και συμμάχων» του δήμου, όπως επίσης και οι Ρωμαίοι είχαν την ίδια πολυτελή μεταχείριση. Το αθηναϊκό πρωτόκολλο, όπως αναβιώνει μέσα από μερικές επιγραφές και κάποιες γραπτές πηγές, προέβλεπε υποδοχή στον Πειραιά από εφήβους και άρχοντες, οι οποίοι συνόδευαν το τιμώμενο πρόσωπο έως την Αθήνα, σε λαμπρή πομπή· πρόκειται για τη λεγόμενη απάντησις. Στη συνέχεια, η παραμονή (αποδοχή) διέπετο επίσης από κανόνες, ενώ την ευθύνη της διεξαγωγής της αναλάμβανε άρχοντας, ειδικά επιφορτισμένος με την υποδοχή· στην Αθήνα η παραμονή περιλάμβανε θυσίες σε δημόσια ιερά, δημόσιο γεύμα αλλά και μια αθηναϊκή ιδιαιτερότητα, την ομιλία ενώπιον των πολιτών.
Optimization in supply chain management, the current state and future directions: A systematic review and bibliometric analysis
Authors: Movahedipour Mahmood , Yang Mengke , Zeng Jianqiu , Wu Xiankang , Salam Shafaq 
Published: November 2016

Purpose: The purpose of this paper is finding the current state of research and identifies high-potential area for future investigation in optimization in supply chain management.Design/methodology/approach: In this paper we present Bibliometric and Network analysis to examine current state research on optimization in supply chain management to identify established and emergent research field for future investigation. The systematic research review which we used in our study have not grasp or assess by other researchers on this topic. Firstly, based on our methodology Bibliometric analysis began by identifying 1610 publications raised from scientific journals, included literatures from 1994 to March of 2016. Secondly, we applied PageRank algorithm in our data for citation analysis to indicate the significance of a publication. Thirdly, the topological decision variables analysis is done based on Louvain method for network data clustering, for this proposes we used the rigorous tools.Finding: Based on our Network analysis result, the optimization in supply chain management research can be divided into four clusters /modules that introduced fundamental skill, knowledge, theory, application and method.Research limitations/implications: We presented some limitation in our research in some fields which could allow new researchers and practitioners conduct the future research to grow up in different dimensions.Practical implications: Practitioners or policy maker usually are not familiar with these type researches so this is why mush of these survey remain in theatrical and conceptual .Future investigation needs to play in practical application domain instead stop merely in opinion. Originality/value: Based on our research, the researchers have more attention to work in conceptual analysis due to other fields but we believe that in facility location problem there many remarkable rooms still exist for future research to development. We also contributed more details in the papers.
Myeloid-Specific Gene Deletion of Protein Phosphatase 2A Magnifies MyD88- and TRIF-Dependent Inflammation following Endotoxin Challenge
Authors: Sun Lei , Pham Tiffany T. , Cornell Timothy T. , McDonough Kelli L. , McHugh Walker M. , Blatt Neal B. , Dahmer Mary K. , Shanley Thomas P. 
Published: November 2016

Abstract
Protein phosphatase 2A (PP2A) is a member of the intracellular serine/threonine phosphatases. Innate immune cell activation triggered by pathogen-associated molecular patterns is mediated by various protein kinases, and PP2A plays a counter-regulatory role by deactivating these kinases. In this study, we generated a conditional knockout of the α isoform of the catalytic subunit of PP2A (PP2ACα). After crossing with myeloid-specific cre-expressing mice, effective gene knockout was achieved in various myeloid cells. The myeloid-specific knockout mice (lyM-PP2Afl/fl) showed higher mortality in response to endotoxin challenge and bacterial infection. Upon LPS challenge, serum levels of TNF-α, KC, IL-6, and IL-10 were significantly increased in lyM-PP2Afl/fl mice, and increased phosphorylation was observed in MAPK pathways (p38, ERK, JNK) and the NF-κB pathway (IKKα/β, NF-κB p65) in bone marrow–derived macrophages (BMDMs) from knockout mice. Heightened NF-κB activation was not associated with degradation of IκBα; instead, enhanced phosphorylation of the NF-κB p65 subunit and p38 phosphorylation-mediated TNF-α mRNA stabilization appear to contribute to the increased TNF-α expression. In addition, increased IL-10 expression appears to be due to PP2ACα-knockout–induced IKKα/β hyperactivation. Microarray experiments indicated that the Toll/IL-1R domain–containing adaptor inducing IFN-β/ TNFR-associated factor 3 pathway was highly upregulated in LPS-treated PP2ACα-knockout BMDMs, and knockout BMDMs had elevated IFN-α/β production compared with control BMDMs. Serum IFN-β levels from PP2ACα-knockout mice treated with LPS were also greater than those in controls. Thus, we demonstrate that PP2A plays an important role in regulating inflammation and survival in the setting of septic insult by targeting MyD88- and Toll/IL-1R domain–containing adaptor inducing IFN-β–dependent pathways.
Blocking Virus Replication during Acute Murine Cytomegalovirus Infection Paradoxically Prolongs Antigen Presentation and Increases the CD8+ T Cell Response by Preventing Type I IFN–Dependent Depletion of Dendritic Cells
Authors: Loo Christopher P. , Snyder Christopher M. , Hill Ann B. 
Published: November 2016

Abstract
Increasing amounts of pathogen replication usually lead to a proportionate increase in size and effector differentiation of the CD8+ T cell response, which is attributed to increased Ag and inflammation. Using a murine CMV that is highly sensitive to the antiviral drug famciclovir to modulate virus replication, we found that increased virus replication drove increased effector CD8+ T cell differentiation, as expected. Paradoxically, however, increased virus replication dramatically decreased the size of the CD8+ T cell response to two immunodominant epitopes. The decreased response was due to type I IFN–dependent depletion of conventional dendritic cells and could be reproduced by specific depletion of dendritic cells from day 2 postinfection or by sterile induction of type I IFN. Increased virus replication and type I IFN specifically inhibited the response to two immunodominant epitopes that are known to be dependent on Ag cross-presented by DCs, but they did not inhibit the response to “inflationary” epitopes whose responses can be sustained by infected nonhematopoietic cells. Our results show that type I IFN can suppress CD8+ T cell responses to cross-presented Ag by depleting cross-presenting conventional dendritic cells.
Accurate Structure Prediction of CDR H3 Loops Enabled by a Novel Structure-Based C-Terminal Constraint
Authors: Weitzner Brian D. , Gray Jeffrey J. 
Published: November 2016

Abstract
Ab structure prediction has made great strides, but accurately modeling CDR H3 loops remains elusive. Unlike the other five CDR loops, CDR H3 does not adopt canonical conformations and must be modeled de novo. During Antibody Modeling Assessment II, we found that biasing simulations toward kinked conformations enables generating low–root mean square deviation models (Weitzner et al. 2014. Proteins 82: 1611–1623), and since then, we have presented new geometric parameters defining the kink conformation (Weitzner et al. 2015. Structure 23: 302–311). In this study, we use these parameters to develop a new biasing constraint. When applied to a benchmark set of high-quality CDR H3 loops, the average minimum root mean square deviation sampled is 0.93 Å, compared with 1.34 Å without the constraint. We then test the performance of the constrained de novo method for homology modeling and rigid-body docking and present the results for 1) the Antibody Modeling Assessment II targets, 2) the 2009 RosettaAntibody benchmark set, and 3) the high-quality set.
Cooling Effectiveness of a Modified Cold-Water Immersion Method After Exercise-Induced Hyperthermia
Authors: Luhring Katherine E. , Butts Cory L. , Smith Cody R. , Bonacci Jeffrey A. , Ylanan Ramon C. , Ganio Matthew S. , McDermott Brendon P. 
Published: November 2016

Context: Recommended treatment for exertional heat stroke includes whole-body cold-water immersion (CWI). However, remote locations or monetary or spatial restrictions can challenge the feasibility of CWI. Thus, the development of a modified, portable CWI method would allow for optimal treatment of exertional heat stroke in the presence of these challenges.Objective: To determine the cooling rate of modified CWI (tarp-assisted cooling with oscillation [TACO]) after exertional hyperthermia.Design: Randomized, crossover controlled trial.Setting: Environmental chamber (temperature = 33.4°C ± 0.8°C, relative humidity = 55.7% ± 1.9%).Patients or Other Participants: Sixteen volunteers (9 men, 7 women; age = 26 ± 4.7 years, height = 1.76 ± 0.09 m, mass = 72.5 ± 9.0 kg, body fat = 20.7% ± 7.1%) with no history of compromised thermoregulation.Intervention(s): Participants completed volitional exercise (cycling or treadmill) until they demonstrated a rectal temperature (Tre) ≥39.0°C. After exercise, participants transitioned to a semirecumbent position on a tarp until either Tre reached 38.1°C or 15 minutes had elapsed during the control (no immersion [CON]) or TACO (immersion in 151 L of 2.1°C ± 0.8°C water) treatment.Main Outcome Measure(s): The Tre, heart rate, and blood pressure (reported as mean arterial pressure) were assessed precooling and postcooling. Statistical analyses included repeated-measures analysis of variance with appropriate post hoc t tests and Bonferroni correction.Results: Before cooling, the Tre was not different between conditions (CON: 39.27°C ± 0.26°C, TACO: 39.30°C ± 0.39°C; P = .62; effect size = −0.09; 95% confidence interval [CI] = −0.2, 0.1). At postcooling, the Tre was decreased in the TACO (38.10°C ± 0.16°C) compared with the CON condition (38.74°C ± 0.38°C; P &lt; .001; effect size = 2.27; 95% CI = 0.4, 0.9). The rate of cooling was greater during the TACO (0.14 ± 0.06°C/min) than the CON treatment (0.04°C/min ± 0.02°C/min; t15 = −8.84; P &lt; .001; effect size = 2.21; 95% CI = −0.13, −0.08). These differences occurred despite an insignificant increase in fluid consumption during exercise preceding CON (0.26 ± 0.29 L) versus TACO (0.19 ± 0.26 L; t12 = 1.73; P = .11; effect size = 0.48; 95% CI = −0.02, 0.14) treatment. Decreases in heart rate did not differ between the TACO and CON conditions (t15 = −1.81; P = .09; effect size = 0.45; 95% CI = −22, 2). Mean arterial pressure was greater at postcooling with TACO (84.2 ± 6.6 mm Hg) than with CON (67.0 ± 9.0 mm Hg; P &lt; .001; effect size = 2.25; 95% CI = 13, 21).Conclusions: The TACO treatment provided faster cooling than did the CON treatment. When location, monetary, or spatial restrictions are present, TACO represents an effective alternative to traditional CWI in the emergency treatment of patients with exertional hyperthermia.
Volitional Spine Stabilization During a Drop Vertical Jump From Different Landing Heights: Implications for Anterior Cruciate Ligament Injury
Authors: Haddas Ram , Hooper Troy , James C. Roger , Sizer Phillip S. 
Published: November 2016

Context:Volitional preemptive abdominal contraction (VPAC) during dynamic activities may alter trunk motion, but the role of the core musculature in positioning the trunk during landing tasks is unclear.Objective:To determine whether volitional core-muscle activation incorporated during a drop vertical jump alters lower extremity kinematics and kinetics, as well as trunk and lower extremity muscle activity at different landing heights.Design:Controlled laboratory study.Setting:Clinical biomechanics laboratory.Patients or Other Participants:Thirty-two young healthy adults, consisting of 17 men (age = 25.24 ± 2.88 years, height = 1.85 ± 0.06 m, mass = 89.68 ± 16.80 kg) and 15 women (age = 23.93 ± 1.33 years, height = 1.67 ± 0.08 m, mass = 89.68 ± 5.28 kg).Intervention(s):Core-muscle activation using VPAC.Main Outcome Measure(s):We collected 3-dimensional ankle, knee, and hip motions, moments, and powers; ground reaction forces; and trunk and lower extremity muscle activity during 0.30- and 0.50-m drop vertical-jump landings.Results:During landing from a 0.30-m height, VPAC performance increased external oblique and semitendinosis activity, knee flexion, and knee internal rotation and decreased knee-abduction moment and knee-energy absorption. During the 0.50-m landing, the VPAC increased external oblique and semitendinosis activity, knee flexion, and hip flexion and decreased ankle inversion and hip-energy absorption.Conclusions:The VPAC performance during landing may protect the anterior cruciate ligament during different landing phases from different heights, creating a protective advantage just before ground contact and after the impact phase. Incorporating VPAC during high injury-risk activities may enhance pelvic stability, improve lower extremity positioning and sensorimotor control, and reduce anterior cruciate ligament injury risk while protecting the lumbar spine.
Imaging Guidance Improves the Results of Viscosupplementation with HANOX-M-XL in Patients with Ankle Osteoarthritis: Results of a Clinical Survey in 50 Patients Treated in Daily Practice
Authors: Bossert Marie , Boublil Daniel , Parisaux Jean-Marc , Bozgan Ana-Maria , Richelme Emmanuel , Conrozier Thierry 
Published: November 2016

Background The objective of this survey was to assess retrospectively the interest of performing viscosupplementation using imaging guidance in patients suffering from ankle osteoarthritis (OA). Patients and Methods This is a multicenter retrospective survey using a standardized questionnaire. Fifty patients suffering from ankle OA and treated, in daily clinical practice, with a single intra-articular injection of a novel viscosupplement made of a combination of a non-animal cross-linked hyaluronan and mannitol, HANOX M-XL, were included in the survey. The injection procedure (imaging or landmark guidance), demographic data, patient's self-evaluation of pain, satisfaction, treatment efficacy, and tolerability were collected. Predictive factors of both efficacy and patient's satisfaction were investigated. Results The percentages of patients very satisfied/satisfied and not really satisfied/dissatisfied with the treatment were 68% and 32%, respectively. Efficacy was rated as very good, good, moderate, and poor by 38%, 30%, 12%, and 20% of the cases, respectively. Efficacy was unrelated to gender and age and was highly correlated with pain score ( P < 0.0001). In satisfied patients, the decrease in consumption of analgesics/non-steroidal anti-inflammatory drugs was >75% in 64% of the cases. Efficacy was significantly different with regard to imaging guidance. There was a statistically significant difference in efficacy and satisfaction between landmark-guided and imaging-guided injections ( P = 0.02). The success rate was 2.3 times higher in the imaging-guided group than in the landmark-guided group. No significant difference was found between patients injected under fluoroscopy or ultrasound guidance, despite a trend favoring ultrasound ( P = 0.09). Tolerability was rated as very good/good in 47 patients, moderate in two, and poor in one and was unrelated to the type of guidance. Conclusion This preliminary study suggests that the use of imaging guidance significantly optimizes the success rate of ankle viscosupplementation. No safety concern was observed. LEVEL OF EVIDENCE III.
Towards simplification of hydrologic modeling: identification of dominant processes
Authors: Markstrom Steven L. , Hay Lauren E. , Clark Martyn P. 
Published: November 2016

Abstract. parameter hydrologic model, has been applied to the conterminous US (CONUS). Parameter sensitivity analysis was used to identify: (1) the sensitive input parameters and (2) particular model output variables that could be associated with the dominant hydrologic process(es). Sensitivity values of 35 PRMS calibration parameters were computed using the Fourier amplitude sensitivity test procedure on 110 000 independent hydrologically based spatial modeling units covering the CONUS and then summarized to process (snowmelt, surface runoff, infiltration, soil moisture, evapotranspiration, interflow, baseflow, and runoff) and model performance statistic (mean, coefficient of variation, and autoregressive lag 1). Identified parameters and processes provide insight into model performance at the location of each unit and allow the modeler to identify the most dominant process on the basis of which processes are associated with the most sensitive parameters. The results of this study indicate that: (1) the choice of performance statistic and output variables has a strong influence on parameter sensitivity, (2) the apparent model complexity to the modeler can be reduced by focusing on those processes that are associated with sensitive parameters and disregarding those that are not, (3) different processes require different numbers of parameters for simulation, and (4) some sensitive parameters influence only one hydrologic process, while others may influence many.
High-resolution monitoring of marine protists based on an observation strategy integrating automated on-board filtration and molecular analyses
Authors: Metfies Katja , Schroeder Friedhelm , Hessel Johanna , Wollschläger Jochen , Micheller Sebastian , Wolf Christian , Kilias Estelle , Sprong Pim , Neuhaus Stefan , Frickenhaus Stephan , Petersen Wilhelm 
Published: November 2016

Abstract. Information on recent biomass distribution and biogeography of photosynthetic marine protists with adequate temporal and spatial resolution is urgently needed to better understand the consequences of environmental change for marine ecosystems. Here we introduce and review a molecular-based observation strategy for high-resolution assessment of these protists in space and time. It is the result of extensive technology developments, adaptations and evaluations which are documented in a number of different publications, and the results of the recently completed field testing which are introduced in this paper. The observation strategy is organized at four different levels. At level 1, samples are collected at high spatiotemporal resolution using the remotely controlled automated filtration system AUTOFIM. Resulting samples can either be preserved for later laboratory analyses, or directly subjected to molecular surveillance of key species aboard the ship via an automated biosensor system or quantitative polymerase chain reaction (level 2). Preserved samples are analyzed at the next observational levels in the laboratory (levels 3 and 4). At level 3 this involves molecular fingerprinting methods for a quick and reliable overview of differences in protist community composition. Finally, selected samples can be used to generate a detailed analysis of taxonomic protist composition via the latest next generation sequencing technology (NGS) at level 4. An overall integrated dataset of the results based on the different analyses provides comprehensive information on the diversity and biogeography of protists, including all related size classes. At the same time the cost of the observation is optimized with respect to analysis effort and time.
The Architecture of American Slavery: Teaching the Black Lives Matter Movement to Architects
Authors: Zipf Catherine 
Published: November 2016

The spatial dynamics surrounding the murder of Trayvon Martin are rarely discussed in architecture schools. Yet, the racial biases in our landscape are key to the agenda of the Black Lives Matter movement. This article tells the story of how these issues found their way into a course on the architecture of American slavery. As the semester progressed, students discovered how the remnants of slave spaces, along with the racial biases they embodied, have contributed to the rise of the Black Lives Matter movement.
A Matter of Debate or Just a Misunderstanding? Woman's Suffrage and the Ambivalence of Writing
Authors: Nichanian Daniel 
Published: November 2016

Abstract
Jacques Rancière defines literarity as texts' propensity to be used in unexpected ways by unforeseen readers. Unlike scholars who view literarity as having intrinsically democratic implications, I contend that Rancière offers a more ambivalent account of its significance. I illustrate my argument by analyzing the aftermath of suffragists' appeal to the U.S. Constitution in the 1870s. I show that public agitation over textual meaning can shore up the perception that a text is indeterminate and allows debate, but it can be cited as well as a symptom of incompetence and duplicity, as evidence that texts should be reserved for those with mastery. Using a text democratically, then, involves more than advocating for innovative interpretations. It also involves struggling for the propriety of treating the meaning of a text as a matter of democratic interaction, against those who treat it as not subject to public debate.
Untology
Authors: Dunne Éamonn 
Published: November 2016

Abstract
What exactly is untology? And why is it important for thinking about teaching effectively? In this article I argue that the most exciting opportunities for pursuing real change in pedagogical practices can be seen in the work of Jacques Rancière, especially in his controversial book The Ignorant Schoolmaster and (as this article traces) in his short essay “What Does It Mean to Be Un?” I argue that what is needed in educators today is an egalitarian aptitude for openness and what I am calling unlearning. Furthermore, through a close reading of Charles Baxter's short story “Gryphon,” I claim that the best teachers today are unqualified to teach. Thinking about qualification, as the current neoliberal regime would have us think about it—as a bankable phenomenon—misses the promise of education as a process of unlearning, unknowing and unbecoming. Education is untology.