bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of sagittal plane mechanics on ACL strain during jump landing
Authors: Bakker Ryan , Tomescu Sebastian , Brenneman Elora , Hangalur Gajendra , Laing Andrew , Chandrashekar Naveen 
Published: January 2016

ABSTRACTThe relationships between non‐contact anterior cruciate ligament injuries and the underlying biomechanics are still unclear, despite large quantities of academic research. The purpose of this research was to study anterior cruciate ligament strain during jump landing by investigating its correlation with sagittal plane kinetic/kinematic parameters and by creating an empirical model to estimate the maximum strain. Whole‐body kinematics and ground reaction forces were measured from seven subjects performing single leg jump landing and were used to drive a musculoskeletal model that estimated lower limb muscle forces. These muscle forces and kinematics were then applied on five instrumented cadaver knees using a dynamic knee simulator system. Correlation analysis revealed that higher ground reaction force, lower hip flexion angle and higher hip extension moment among others were correlated with higher peak strain (p < 0.05). Multivariate regression analyses revealed that intrinsic anatomic factors account for most of the variance in strain. Among the extrinsic variables, hip and trunk flexion angles significantly contributed to the strain. The empirical relationship developed in this study could be used to predict the relative strain between jumps of a participant and may be beneficial in developing training programs designed to reduce an athlete's risk of injury. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1636–1644, 2016.
Simple Theoretical Considerations for Block‐Copolymer‐Based Plasmonic Metamaterials
Authors: Malafronte Anna , Capretti Antonio , Pepe Giovanni P. , Forestiere Carlo , Miano Giovanni , Auriemma Finizia , De Rosa Claudio , Di Girolamo Rocco 
Published: January 2016

SummaryBlock‐copolymers (BCPs) self‐assembling provides a unique tool for realizing large‐area ordered metamaterials with desired optical properties due to the rich range of tunable nano‐morphologies and to the chemical properties of the block polymers that can lead to the selective inclusion of functionalized nanoparticles (NPs) in specific nanodomains, generating periodic arrays of NPs according to the geometry of the BCP acting as template. In this work, we investigate nanostructured thin films of polystyrene‐block‐poly(methylmethacrylate) (PS‐PMMA) BCP filled with functionalized metallic (Au) nanoparticles. The BCP is characterized by an hexagonal array of PS cylinders in the PMMA matrix and the Au NPs are selectively included in the PS cylindrical domains. The optical properties of such nano‐structures are strongly affected by localized surface plasmons (LSPs) in the NPs. We theoretically demonstrate that the optical properties of such nano‐structures can be tuned by varying the NPs loading concentration and the NPs radius. Then, we investigate the effects of the hexagonal geometry on the collective plasmonic oscillations. We fabricated the PS‐PMMA/Au NPs composite and we experimentally demonstrate the existence of collective plasmonic resonances of gold nanoparticles after an electromagnetic stimulation, arising from the ordered arrangement of AuNPs in the periodic array of hexagonally packed cylinders created by BCP self‐assembly. This approach allows a fine modulation of the NPs optical properties and can be used as an intriguing and versatile tool to build useful devices for Optics & Photonics applications, with significant benefits for both fundamental and applied investigations.
Monolithic Polymeric Aerogels with Organically Modified Clays and Graphite Oxide Nanofillers
Authors: Longo Simona , Mauro Marco , Guerra Gaetano 
Published: January 2016

SummaryIn this contribution the preparation of composite syndiotactic polystyrene (s‐PS) monolithic aerogels with nanofillers such as organically modified montmorillonite (OMMT) and graphene oxide (GO) is described. In these aerogels the crystallites that constitute the physical knots exhibit a nanoporous‐crystalline form. The aerogels preparation procedure allows the inclusion of also large amount of nanofillers, without aggregation, at least up to a content of 20 wt.%. This allows to improve mechanical and electrical properties of the nanoporous‐crystalline aerogels of s‐PS, which are particularly suitable to remove selectively traces of pollutants from water and air. Composite aerogels exhibiting large nanofiller content, can be also used as masterbatches for polymer composites.
Gradient‐based electrical conductivity imaging using MR phase
Authors: Gurler Necip , Ider Yusuf Ziya 
Published: January 2016

PurposeTo develop a fast, practically applicable, and boundary artifact free electrical conductivity imaging method that does not use transceive phase assumption, and that is more robust against the noise.TheoryStarting from the Maxwell's equations, a new electrical conductivity imaging method that is based solely on the MR transceive phase has been proposed. Different from the previous phase based electrical properties tomography (EPT) method, a new formulation was derived by including the gradients of the conductivity into the equations.MethodsThe governing partial differential equation, which is in the form of a convection‐reaction‐diffusion equation, was solved using a three‐dimensional finite‐difference scheme. To evaluate the performance of the proposed method numerical simulations, phantom and in vivo human experiments have been conducted at 3T.ResultsSimulation and experimental results of the proposed method and the conventional phase–based EPT method were illustrated to show the superiority of the proposed method over the conventional method, especially in the transition regions and under noisy data.ConclusionWith the contributions of the proposed method to the phase‐based EPT approach, a fast and reliable electrical conductivity imaging appears to be feasible, which is promising for clinical diagnoses and local SAR estimation. Magn Reson Med 77:137–150, 2017. © 2016 Wiley Periodicals, Inc.
Robust and efficient monolithic fluid‐structure‐interaction solvers
Authors: Langer Ulrich , Yang Huidong 
Published: January 2016

SummaryWe construct new robust and efficient preconditioned generalized minimal residual solvers for the monolithic linear systems of algebraic equations arising from the finite element discretization and Newton's linearization of the fully coupled fluid–structure interaction system of partial differential equations in the arbitrary Lagrangian–Eulerian formulation. We admit both linear elastic and nonlinear hyperelastic materials in the solid model and cover a large range of flows, for example, water, blood, and air, with highly varying density. The preconditioner is constructed in form of, where,, andare proper approximations to the matricesL,D, andUin theLDUblock factorization of the fully coupled system matrix, respectively. The inverse of the corresponding Schur complement is approximated by applying a few cycles of a special class of algebraic multigrid methods to the perturbed fluid sub‐problem, which is obtained by modifying corresponding entries in the original fluid matrix with an explicitly constructed approximation to the exact perturbation coming from the sparse matrix–matrix multiplications. The numerical studies presented impressively demonstrate the robustness and the efficiency of the preconditioner proposed in the paper. Copyright © 2016 John Wiley & Sons, Ltd.
Body temperature triggered shape‐memory polymers with high elastic energy storage capacity
Authors: Meng Yuan , Jiang Jisu , Anthamatten Mitchell 
Published: January 2016

ABSTRACTShape‐memory polymers (SMPs) that respond near body temperature are attracting broad interest, especially in the biomedical fields. In this study, the triggering temperature of poly(caprolactone) SMP networks is precisely adjusted by inclusion of non‐crystallizable molecular linkers and by variation of prepolymer molecular weight. Longer, non‐crystalline linkers and lower molecular weight prepolymers interfere with crystallization, lowering the transition temperature. Networks are prepared with crystallization temperatures that are beneath the human body temperature and yet are above room temperature. Upon cooling such amorphous networks to room temperature, crystallization is sluggish. There, elastomers can be easily strained by several hundred‐percent to induce crystallization, thereby fixing strained states. If subsequently heated, programmed SMPs can release significant amounts of stored strain energy (∼3 MJ/m3). SMPs that combine elastic energy storage and exhibit triggering temperatures near the human body temperature could benefit emerging applications in the biomedical space. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016, 54, 1397–1404
Repetitive responses to nanoparticle albumin‐bound paclitaxel and carboplatin in malignant pleural mesothelioma
Authors: Kanai Osamu , Fujita Kohei , Nakatani Koichi , Mio Tadashi 
Published: January 2016

AbstractMalignant pleural mesothelioma (MPM) is a rare tumor with a poor prognosis. Although cisplatin plus pemetrexed is the standard chemotherapy for patients with unresectable MPM, few agents are available for MPM patients who do not tolerate pemetrexed. Here, we report the first case of an MPM patient for whom the combination of nanoparticle albumin‐bound paclitaxel and carboplatin (nabPC) repetitively achieved tumor regression. A 76‐year‐old man was diagnosed with epithelioid MPM. One cycle of carboplatin plus pemetrexed and two cycles of gemcitabine were administered but failed to inhibit tumor progression. By contrast, four cycles of nabPC resulted in a good response. Upon disease progression, four cycles of nabPC were performed again and resulted in a modest response. In conclusion, based on the present case, nabPC is a potential alternative chemotherapeutic agent for MPM, especially for MPM patients who do not tolerate pemetrexed.
Response pattern analysis: Assuring data integrity in extreme research settings
Authors: Christensen Lisa Jones , Siemsen Enno , Branzei Oana , Viswanathan Madhu 
Published: January 2016

Research summary: Strategy scholars increasingly conduct research in nontraditional contexts. Such efforts often require the assistance of third‐party intermediaries who understand local culture, norms, and language. This reliance on intermediation in primary or secondary data collection can elicit agency breakdowns that call into question the reliability, analyzability, and interpretability of responses. Herein, we investigate the causes and consequences of intermediary bias in the form of faked data and we offer Response Pattern Analysis as a statistical solution for identifying and removing such problematic data. By explicating the effect, illustrating how we detected it, and performing a controlled field experiment in a developing country to test the effectiveness of our methodological solution, we encourage researchers to continue to seek data and build theory from unique and understudied settings.Managerial summary: Any form of survey research contains the risk of interviewers faking data. This risk is particularly difficult to mitigate in Base‐of‐Pyramid or developing country contexts where researchers have to rely on intermediaries and forms of control are limited. We provide a statistical technique to identify a faking interviewer's ex post data collection, and remove the associated data prior to analysis. Using a field experiment where we instruct interviewers to fake the data, we demonstrate that the algorithm we employ achieves a 90 percent accuracy in terms of differentiating faking from nonfaking interviewers. Copyright © 2016 John Wiley & Sons, Ltd.
New record of Egertonia (Elopiformes, Phyllodontidae) from the Late Cretaceous of South India
Authors: Halliday Thomas J. D. , Cuff Andrew R. , Prasad Guntupalli V. R. , Thanglemmoi Mechek S. , Goswami Anjali 
Published: January 2016

AbstractWe report a new occurrence of the phyllodontid teleost fish Egertonia from the Late Cretaceous Kallamedu Formation of the Cauvery Basin, South India. This is the oldest occurrence of Phyllodontidae in India, and only the second Cretaceous Gondwanan occurrence of this genus, following a toothplate previously described from the Late Cretaceous Maevarano Formation, Madagascar. The presence of phyllodontid fish supports a fluvial–deltaic or brackish environment for the lower part of the Kallamedu Formation, a rich deposit including typically Gondwanan taxa, such as simosuchid crocodiles, bothremydid turtles and abelisaurid dinosaurs, as well as an anomalous troodontid dinosaur. Egertonia adds another taxon of primarily Laurasian distribution to the Kallamedu fauna and further expands the list of taxa known from the Late Cretaceous of both India and Madagascar, strengthening the degree of faunal similarity between the two landmasses in the latest Cretaceous.
Surgical treatment of Cesarean scar ectopic pregnancy: efficacy and safety of ultrasound‐guided suction curettage
Authors: Jurkovic D. , Knez J. , Appiah A. , Farahani L. , Mavrelos D. , Ross J. A. 
Published: January 2016

ABSTRACTObjectivesTo assess the efficacy of ultrasound‐guided suction curettage for management of pregnancies implanted into the lower uterine segment Cesarean section scar.MethodsThis was a retrospective study including women diagnosed with Cesarean section scar pregnancy at two large tertiary referral early pregnancy units between 1997 and 2014. Surgical evacuation was offered to selected women presenting in the first trimester ≤ 14 weeks' gestation. All procedures were performed transcervically under ultrasound guidance using suction curettage. A modified Shirodkar cervical suture was used in women who required additional measures to secure hemostasis.ResultsA total of 232 women with Cesarean section scar pregnancy were seen at the referral units; 191/232 (82.3%) women were treated surgically. The median intraoperative blood loss was 100 mL (range, 10–3000 mL); 9/191 (4.7% (95% CI, 1.7–7.7%)) women required blood transfusion and, in one (0.5% (95% CI, 0–1.5%)), life‐saving hysterectomy had to be performed because of uncontrollable intraoperative bleeding. Of the women who attended for follow‐up, 7/116 (6.0% (95% CI, 1.7–10.3%)) required a repeat surgical procedure because of retained products of conception. Multivariable analysis showed that the gestational sac diameter (odds ratio (OR), 1.10 (95% CI, 1.03–1.17)) and pregnancy vascularity on Doppler examination (OR, 3.41 (95% CI, 1.39–8.33)) were significant predictors of heavy intraoperative blood loss (> 1000 mL).ConclusionsUltrasound‐guided suction curettage is an effective method for the treatment of pregnancies implanted into a lower uterine segment Cesarean section scar and is associated with a low risk of blood transfusion and hysterectomy. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.
pH‐Sensitive stimulus‐responsive nanocarriers for targeted delivery of therapeutic agents
Authors: Karimi Mahdi , Eslami Masoud , Sahandi‐Zangabad Parham , Mirab Fereshteh , Farajisafiloo Negar , Shafaei Zahra , Ghosh Deepanjan , Bozorgomid Mahnaz , Dashkhaneh Fariba , Hamblin Michael R. 
Published: January 2016

In recent years miscellaneous smart micro/nanosystems that respond to various exogenous/endogenous stimuli including temperature, magnetic/electric field, mechanical force, ultrasound/light irradiation, redox potentials, and biomolecule concentration have been developed for targeted delivery and release of encapsulated therapeutic agents such as drugs, genes, proteins, and metal ions specifically at their required site of action. Owing to physiological differences between malignant and normal cells, or between tumors and normal tissues, pH‐sensitive nanosystems represent promising smart delivery vehicles for transport and delivery of anticancer agents. Furthermore, pH‐sensitive systems possess applications in delivery of metal ions and biomolecules such as proteins, insulin, etc., as well as co‐delivery of cargos, dual pH‐sensitive nanocarriers, dual/multi stimuli‐responsive nanosystems, and even in the search for new solutions for therapy of diseases such as Alzheimer's. In order to design an optimized system, it is necessary to understand the various pH‐responsive micro/nanoparticles and the different mechanisms of pH‐sensitive drug release. This should be accompanied by an assessment of the theoretical and practical challenges in the design and use of these carriers. WIREs Nanomed Nanobiotechnol 2016, 8:696–716. doi: 10.1002/wnan.1389This article is categorized under:

Biology-Inspired Nanomaterials > Lipid-Based Structures
Therapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic Disease
Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease
Effects of a higher dose of alglucosidase alfa on ventilator‐free survival and motor outcome in classic infantile Pompe disease: an open‐label single‐center study
Authors: van Gelder C. M. , Poelman E. , Plug I. , Hoogeveen‐Westerveld M. , van der Beek N. A. M. E. , Reuser A. J. J. , van der Ploeg A. T. 
Published: January 2016

AbstractBackgroundThough enzyme‐replacement therapy (ERT) with alglucosidase alfa has significantly improved the prospects for patients with classic infantile Pompe disease, some 50 % of treated infants do not survive ventilator‐free beyond the age of 3 years. We investigated whether higher and more frequent dosing of alglucosidase alfa improves outcome.MethodsEight cross‐reactive immunological material (CRIM) positive patients were included in the study. All had fully deleterious mutations in both GAA alleles. Four received a dose of 20 mg/kg every other week (eow) and four received 40 mg/kg/week. Survival, ventilator‐free survival, left‐ventricular mass index (LVMI), motor outcome, infusion‐associated reactions (IARs), and antibody formation were evaluated.ResultsAll eight patients were alive at study end, seven of them remained ventilator‐free. The patient who became ventilator dependent was treated with 20 mg/kg eow. Three of the four patients receiving 20 mg/kg eow learned to walk; two of them maintained this ability at study end. All four patients receiving 40 mg/kg/week acquired and maintained the ability to walk at study end (ages of 3.3–5.6 years), even though their baseline motor functioning was poorer. There were no apparent differences between the two dose groups with respect to the effect of ERT on LVMI, the number of IARs and antibody formation.ConclusionsOur data may suggest that a dose of 40 mg/kg/week improves outcome of CRIM positive patients over that brought by the currently recommended dose of 20 mg/kg eow. Larger studies are needed to draw definite conclusions.
U-Pb SHRIMP Ages of Detrital Zircons from Hiriyur Formation in Chitradurga Greenstone Belt and its Implication to the Neoarchean Evolution of Dharwar Craton, South India
Authors: Nasheeth A. , Okudaira T. , Horie K. , Hokada T. , Satish-Kumar M. 
Published: January 2016

Abstract:
We report newly obtained U-Pb SHRIMP ages of detrital zircons from metagreywackes in the Hiriyur Formation (Chitradurga Group, Dharwar Supergroup) from the central eastern part of the Chitradurga greenstone belt. U-Pb analyses yield three major Neoarchean age populations ranging from 2.70–2.54 Ga with some minor age population of Mesoarchean. The maximum age of deposition is constrained by the youngest detrital zircon population at 2546 Ma. This is the first report of the occurrence of supracrustal rocks less than 2.58 Ga in the central part of Chitradurga greenstone belt. Close evaluation of detrital ages with the published ages of surrounding igneous rocks suggest that the youngest detrital zircons might be derived from rocks of the Eastern Dharwar craton and the inferred docking of the western and eastern Dharwar cratons happened prior to the deposition of the Hiriyur Formation. The Chitradurga shear zone, dividing the Dharwar craton into western and eastern blocks, probably developed after the deposition. Furthermore, the lower intercept is interpreted as evidence for the Pan-African overprints in the study area.
A Note on Chemical Composition and Origin of Ferromanganese Oxide Coated and Uncoated Pumice Samples from Central Indian Ocean Basin
Authors: Pattan J. N. , Parthiban G. , Moraes C. , Rajalakshmi R. , Lekshmi S. , Athira S. , Sankar S. Jai 
Published: January 2016

Abstract:
Pumice are explosive volcanic product, occur as uncoated or coated with ferromanganese (Fe-Mn) oxide and resides in association with ferromanganese nodules on the seabed in Central Indian Ocean Basin (CIOB). The older Fe-Mn oxide coated and younger uncoated pumice clasts were leached with 6N HCl to remove Fe-Mn oxide coatings as well as the calcium carbonate present within the vesicles. The main objective of the present study is to understand the origin of these pumice by utilizing their chemical composition. Both coated and uncoated pumice samples are rhyolite- and medium K calc-alkaline series. Major, trace, rare earth elements (ΣREE) concentration and chondrite-normalized REE patterns of both coated and uncoated pumice are nearly similar to each other suggesting a same source. Tectonomagmatic discrimination diagrams (Nb vs Y: Yb vs. Ta), triangular plot (TiO2-Zr-Y) and High Field Strength Element ratios (La/Ta- 25; Ta/Hf- 0.2; Nb/Ta- 9; Zr/Nb- 22 and Ba/Ta-1084) indicate volcanic arc origin. These were probably sourced from the nearest Indonesian volcanic arc and drifted to the CIOB by currents.
Postoperative pain documentation in a hospital setting: A topical review
Authors: Heikkilä Kristiina , Peltonen Laura-Maria , Salanterä Sanna 
Published: January 2016

Abstract

Background and aims
Nursing documentation supports continuity of care and provides important means of communication among clinicians. The aim of this topical review was to evaluate the published empirical studies on postoperative pain documentation in a hospital setting.

Methods
The review was conducted through a systematic search of electronic databases: Web of Science, PubMed/Medline, CINAHL, Embase, Ovid/Medline, Scopus and Cochrane Library. Ten studies were included. Study designs, documented postoperative pain information, quality of pain documentation, reported quality of postoperative pain management and documentation, and suggestions for future research and practice improvements were extracted from the studies.

Results
The most commonly used study design was a descriptive retrospective patient record review. The most commonly reported types of information were pain assessment, use of pain assessment tools, useof pain management interventions, reassessment, types of analgesics used, demographic information and pain intensity. All ten studies reported that the quality of postoperative pain documentation does not meet acceptable standards and that there is a need for improvement. The studies found that organization of regular pain management education for nurses is important for the future.

Conclusions
Postoperative pain documentation needs to beimproved. Regular educational programmes and development of monitoring systems for systematic evaluation of pain documentation are needed. Guidelines and recommendations should be based on the latest research evidence, and systematically implemented into practice.

Implications
Comprehensive auditing tools for evaluation of pain documentation can make quality assessment easier and coherent. Specific and clear documentation guidelines are needed and existing guidelines should be better implemented into practice. There is a need to increase nurses’ knowledge of postoperative pain management, assessment and documentation. Studies evaluating effectiveness of high quality pain documentation are required.