bluuebunny/crossref_metadata_2025_split huggingface dataset:
La fabrique des territoires du « bien vieillir » : recompositions du thermalisme et gouvernement municipal en France. Le cas de Bagnoles de l’Orne (Normandie)
Authors: Sonnet Adrien , Lestrelin Ludovic , Honta Marina 
Published: November 2017

Avec l’instauration de la Sécurité sociale et le remboursement des cures par l’Assurance maladie, les stations thermales françaises sont, au sortir de la Seconde Guerre mondiale, consacrées comme des territoires d’accompagnement des pathologies et affections qui marquent l’avancée en âge. Intervient néanmoins, au cours des années 1990, une remise en cause par les pouvoirs publics du service médical rendu par les soins thermaux. Cette menace précipite la mobilisation des acteurs du thermalisme pour défendre les intérêts de la filière auprès de l’État. Organisés nationalement, ils cherchent alors à rappeler leur légitimité et leur savoir-faire dans la prise en charge du vieillissement pathologique. Mais ils se saisissent également du paradigme du « bien vieillir » et du « vieillissement actif », voyant là une opportunité de croissance pour relancer une activité par ailleurs fragilisée par la chute de fréquentation des établissements thermaux. Située en Normandie, la station de Bagnoles de l’Orne constitue un cas d’étude pour observer, au niveau local, la recomposition du thermalisme. Accompagnée et orientée par les élus dans un souci d’attractivité territoriale, la modernisation de l’offre thermale bouleverse des équilibres anciens. Ainsi deux vieillesses tendent-elles désormais à cohabiter sur ce territoire. Cherchant à adapter la cure aux enjeux récents de santé publique, les professionnels du thermalisme entendent continuer à accueillir des patients âgés et malades. S’est toutefois développée une seconde approche du vieillissement. Centrée sur la prévention, l’activité physique et le bien-être à destination d’un public bien portant et solvable, elle s’accorde avec la montée des injonctions au vieillissement réussi.
Relier le séparé, séparer le relié. Enquête sur l’accompagnement des personnes atteintes de la maladie d’Alzheimer en EHPAD
Authors: Villez Marion 
Published: November 2017

Cette contribution se centre sur l’accompagnement professionnel en hébergement collectif (singulièrement en établissement d’hébergement pour personnes âgées dépendantes – EHPAD) des personnes atteintes de maladies d’Alzheimer ou de maladies apparentées. Elle analyse la manière dont cet accompagnement est pensé et l’expérience effective qu’en font tant les encadrants que les professionnels de première ligne. La question des modes d’accompagnement des personnes atteintes de troubles cognitifs en établissement d’hébergement est largement spatialisée, principalement au travers de l’identification d’unités dites spécifiques au sein des établissements. À partir d’une enquête qualitative au sein d’un corpus d’établissements en France, il apparaît que, bien que le débat soit sans cesse rejoué, cette spécialisation s’est imposée comme la forme incontournable d’adaptation au nouveau « public cible » constitué par les personnes atteintes de troubles cognitifs, invisibilisant par le fait même l’autre voie qui aurait pu s’avérer une réelle alternative : l’absence d’unités spécifiques. Il est également mis en évidence que la réalité, au quotidien, est plus complexe. Afin de « faire tenir ensemble » la collectivité des résidents, les professionnels construisent et réinventent sans cesse de subtils équilibres « dosant » les formes de spécialisation. Il s’opère ainsi une « pensée du commun en actes » autour d’une double tension : relier le séparé et séparer le relié.
Léon Dion et sa nation ou La dernière voix d’une troisième voie
Authors: Lemieux Olivier 
Published: November 2017

Le travail de Léon Dion, un des pères des sciences politiques au Québec, est reconnu depuis longtemps. Néanmoins, dans le champ de l’historiographie, force est de constater que ce dernier a très peu attiré l’attention des chercheurs. L’article suivant pose l’hypothèse que cet oubli est le résultat d’un malaise suscité par un aspect de sa pensée, lequel fait la promotion d’une troisième voie : le fédéralisme asymétrique. Pour étayer cette hypothèse, nous explorons chronologiquement les principaux travaux de Dion sur la nation, sur le nationalisme et sur la question nationale en les mettant en perspective avec les travaux de quelques intellectuels de son époque. Nous en venons à la conclusion que Dion a été la dernière voix de cette troisième voie.
Enumeration, Ranking and Generation of Binary Trees Based on Level-Order Traversal Using Catalan Cipher Vectors
Authors: Božinovski Adrijan , Stojčevska Biljana , Pačovski Veno 
Published: November 2017

In this paper, a new representation of a binary tree is introduced, called the Catalan Cipher Vector, which is a vector of elements with certain properties. It can be ranked using a special form of the Catalan Triangle designed for this purpose. It is shown that the vector coincides with the level-order traversal of the binary tree and how it can be used to generate a binary tree from it. Streamlined algorithms for directly obtaining the rank from a binary tree and vice versa, using the Catalan Cipher Vector during the processes, are given. The algorithms are analyzed for time and space complexity and shown to be linear for both.The Catalan Cipher Vector enables a straightforward determination of the position and linking for every node of the binary tree, since it contains information for both every node’s ancestor and the direction of linking from the ancestor to that node. Thus, it is especially well suited for binary tree generation. Using another structure, called a canonical state-space tableau, the relationship between the Catalan Cipher Vector and the level-order traversal of the binary tree is explained.
Cultural Dimension of Sustainable Development as a Presumtion of Local Communities Development
Authors: Miltojević Vesna , Ilić-Krstić Ivana 
Published: November 2017

The term “sustainable” can be found in both science and practice. As a global concept of development, it was accepted at the Conference in Rio de Janeiro in 1992 in order to overcome and find a possible way of dealing with problems connected to the development of contemporary civilization. Three dimensions of sustainable development are usually mentioned: economic, social and ecological. The paper points out the significance of the fourth dimension – cultural dimension, which is not only significant for reaching development in the real sense of the world, but it also represents the basis for the development of local communities. The cultural dimension respects the particularities of local communities and emphasizes the maintenance of the cultural and national variety which is of special significance for multicultural societies.
Držanje tijela kod djevojčica uzrasta od 7-15 godina u odnosu na njihov indeks tjelesne mase // Body Posture of Girls Aged 7-15 in Relation to Their Body Mass Index
Authors: Łubkowska Wioletta , Szark-Eckardt Mirosława , Żukowska Hanna , Bendíková Elena , Pavlović Ratko 
Published: November 2017

Uprkos značajnim teorijskim izvorima koji se odnose na loše držanje kod djece i adolescenata, a koje je izazvala promjena načina života, saznanja o problemu abnormalne kičmene krivine treba da budu dopunjena. Može se uvidjeti sve veći broj gojazne djece i ovaj problem težine može dovesti do veće učestalosti lošeg držanja tijela. Ovaj rad ima za cilj da utvrdi učestalost dobrog i lošeg držanja tijela kod djevojčica u odnosu na njihove tjelesne težine, kao i da otkrije da li prekomjerna težina (gojaznost) daju predispoziciju za loše držanje. Istraživanje je obuhvatilo 500 djevojčica uzrasta 7-15 godina, koje žive u Szczecinu u Poljskoj. U procjeni držanja tjela, korišćena je sferosomatometrijska metoda Ivanovskog. Djevojčice sa normalnom tjelesnom težinom su predstavljale 77,7% ispitanika. U 6,7% slučajeva, identifikovana je nedovoljna tjelesna težina. 11,3% su imale višak kilograma , dok je 4,3% djevojčica bilo gojazno - što iznosi 15,6 % ispitanica. Nepravilno držanje tijela je identifikovano u 32,4% ispitanica. Najveći broj djevojčica sa lošim držanjem tijela pronađeno je među 9-godišnjakinjama (38,6%), 13-godišnjakinjama (35.2 %) i 15-godišnjakinjama (35,1%). Prekomjerna težina i gojaznost je bila predispozicija kod ispitanica za pojavu nepravilnog držanja kičme: abnormalna kičmena krivina je pronađena u 30,8% gojaznih djevojčica i djevojčica sa prekomjernom težinom.
Whole genome sequencing of Rhodotorula mucilaginosa isolated from the chewing stick (Distemonanthus benthamianus): insights into Rhodotorula phylogeny, mitogenome dynamics and carotenoid biosynthesis
Authors: Gan Han Ming , Thomas Bolaji N. , Cavanaugh Nicole T. , Morales Grace H. , Mayers Ashley N. , Savka Michael A. , Hudson André O. 
Published: November 2017

In industry, the yeast Rhodotorula mucilaginosa is commonly used for the production of carotenoids. The production of carotenoids is important because they are used as natural colorants in food and some carotenoids are precursors of retinol (vitamin A). However, the identification and molecular characterization of the carotenoid pathway/s in species belonging to the genus Rhodotorula is scarce due to the lack of genomic information thus potentially impeding effective metabolic engineering of these yeast strains for improved carotenoid production. In this study, we report the isolation, identification, characterization and the whole nuclear genome and mitogenome sequence of the endophyte R. mucilaginosa RIT389 isolated from Distemonanthus benthamianus, a plant known for its anti-fungal and antibacterial properties and commonly used as chewing sticks. The assembled genome of R. mucilaginosa RIT389 is 19 Mbp in length with an estimated genomic heterozygosity of 9.29%. Whole genome phylogeny supports the species designation of strain RIT389 within the genus in addition to supporting the monophyly of the currently sequenced Rhodotorula species. Further, we report for the first time, the recovery of the complete mitochondrial genome of R. mucilaginosa using the genome skimming approach. The assembled mitogenome is at least 7,000 bases larger than that of Rhodotorula taiwanensis which is largely attributed to the presence of large intronic regions containing open reading frames coding for homing endonuclease from the LAGLIDADG and GIY-YIG families. Furthermore, genomic regions containing the key genes for carotenoid production were identified in R. mucilaginosa RIT389, revealing differences in gene synteny that may play a role in the regulation of the biotechnologically important carotenoid synthesis pathways in yeasts.
The Defining Characteristics of ENSO Extremes and the Strong 2015/2016 El Niño
Authors: Santoso Agus , Mcphaden Michael J. , Cai Wenju 
Published: November 2017

AbstractThe year 2015 was special for climate scientists, particularly for the El Niño Southern Oscillation (ENSO) research community, as a major El Niño finally materialized after a long pause since the 1997/1998 extreme El Niño. It was scientifically exciting since, due to the short observational record, our knowledge of an extreme El Niño has been based only on the 1982/1983 and 1997/1998 events. The 2015/2016 El Niño was marked by many environmental disasters that are consistent with what is expected for an extreme El Niño. Considering the dramatic impacts of extreme El Niño, and the risk of a potential increase in frequency of ENSO extremes under greenhouse warming, it is timely to evaluate how the recent event fits into our understanding of ENSO extremes. Here we provide a review of ENSO, its nature and dynamics, and through analysis of various observed key variables, we outline the processes that characterize its extremes. The 2015/2016 El Niño brings a useful perspective into the state of understanding of these events and highlights areas for future research. While the 2015/2016 El Niño is characteristically distinct from the 1982/1983 and 1997/1998 events, it still can be considered as the first extreme El Niño of the 21st century. Its extremity can be attributed in part to unusually warm condition in 2014 and to long‐term background warming. In effect, this study provides a list of physically meaningful indices that are straightforward to compute for identifying and tracking extreme ENSO events in observations and climate models.
Synthesis of Carbazoles from 2‐Iodobiphenyls by Palladium‐Catalyzed C−H Activation and Amination with Diaziridinone
Authors: Shao Changdong , Zhou Bo , Wu Zhuo , Ji Xiaoming , Zhang Yanghui 
Published: November 2017

AbstractA facile and efficient approach has been developed for the synthesis of carbazoles from 2‐iodobiphenyls and diaziridinone under palladium catalysis. A wide range of carbazoles were synthesized in good to excellent yields, and indole derivatives were obtained by using styrenes as the substrate. The palladacycles obtained from 2‐iodobiphenyls acted as the key intermediate, and the reaction should proceed via a tandem Pd‐catalyzed C−H activation/dual C−N bond formation sequence.magnified image
Lewis Acid‐Catalyzed Reductive Amination of Aldehydes and Ketones with N,N‐Dimethylformamide as Dimethylamino Source, Reductant and Solvent
Authors: Yang Luo , Lin Jie , Kang Lei , Zhou Wang , Ma Da‐You 
Published: November 2017

AbstractA practical zinc acetate dihydrate‐catalyzed reductive amination of various carbonyl compounds with N,N‐dimethylformamide (DMF) as dimethylamino (Me2N) source, reductant and solvent has been developed. This reaction shows broad substrate scope, good functional group tolerance, avoids the need for a pressure‐proof reactor and column chromatographic isolation operations and gives up to 98% yield, to make it an attractive method for the preparation of tertiary N,N‐dimethylamines.magnified image
Organocatalytic Nitroaldol Reaction Associated with Deuterium‐Labeling
Authors: Yamada Tsuyoshi , Kuwata Marina , Takakura Ryoya , Monguchi Yasunari , Sajiki Hironao , Sawama Yoshinari 
Published: November 2017

AbstractA deuterium‐labeling reaction of nitroalkanes in deuterium oxide and the subsequent nitroaldol reaction have been accomplished under basic and organocatalytic conditions to provide the deuterium‐labeled β‐nitroalcohols in high yields and high deuterium contents. β‐Deuterated β‐nitroalcohols could be smoothly obtained from the reaction of nitroalkanes and various electrophiles using the easily‐removal basic resin WA30. Furthermore, the asymmetric nitroaldol reaction using nitromethane and α‐keto esters as electrophiles in the presence of a quinine‐derived organocatalyst in deuterium oxide could provide the desired β‐deuterated nitroalcohol derivatives with high enantioselectivities.magnified image
Palladium‐Catalyzed Dehydrogenation of Benzyl Alcohols for Construction of 2‐Arylbenzimidazoles “On Water”
Authors: Hikawa Hidemasa , Ichinose Risa , Kikkawa Shoko , Azumaya Isao 
Published: November 2017

AbstractAn “on water” synthetic strategy for the selective construction of 2‐arylbenzimidazoles involving the dehydrogenation of benzyl alcohols by a π‐benzylpalladium(II) system has been developed. This simple oxidant‐ and base‐free protocol can be achieved under mild conditions in an atom‐economic process from o‐phenylenediamines and benzyl alcohols, affording the desired products in moderate to excellent yields. Notably, the “on water” protocol is essential for achieving this new synthetic method in our catalytic system.
Direct intranasal application of the solid phase of ImmunoCAP® increases nasal specific immunoglobulin E detection in local allergic rhinitis patients
Authors: Campo Paloma , del Carmen Plaza‐Seron María , Eguiluz‐Gracia Ibon , Verge Jesús , Galindo Luisa , Barrionuevo Esther , Fernandez Javier , Jurado Raquel , Mayorga Cristobalina , Torres María José , Rondón Carmen 
Published: November 2017

BackgroundThe measurement of nasal specific IgE (NsIgE) in local allergic rhinitis (LAR) patients is challenging and shows variability. The objective of this work was to evaluate a minimally‐invasive method of direct detection of NsIgE in patients with LAR to Dermatophagoides pteronyssinus (DP) using an automated immunoassay.MethodsFifty patients participated (LAR, n = 14; allergic rhinitis (AR), n = 20; healthy controls [HC], n = 16). Detection of NsIgE was performed by direct application of the solid phase of a commercial DP ImmunoCAP® test 24 hours after DP nasal provocation.ResultsThere was no difference in the median volume of secretion absorbed by the solid phase of the ImmunoCAP test in the 3 studied groups (p = 0.17). According to receiver operating characteristic (ROC) curve analysis, NsIgE ≥0.1450 was the optimal cutoff point, obtaining in LAR patients 42.86% sensitivity with the highest specificity (100%), and 75% sensitivity and 100% specificity for AR.ConclusionThis study demonstrates the detection of NsIgE to DP in LAR by using a simple, commercial device with high specificity.
Characteristic Attributes of Multiple Cascaded Terahertz Metasurfaces with Magnetically Tunable Subwavelength Resonators
Authors: Serebryannikov Andriy E. , Lakhtakia Akhlesh , Ozbay Ekmel 
Published: November 2017

AbstractThe characteristics of multiple cascaded metasurfaces comprising H‐shaped, magnetostatically controllable, subwavelength terahertz (THz) resonators made of InAs were systematically investigated, using a commercial solver based on the finite‐integration method, for the design of tunable filters. Three configurations of the biasing magnetostatic field were compared with each other as well as with the bias‐free configuration for filtering of normally incident linearly polarized plane waves. A close study of only one metasurface was found sufficient to broadly determine the sensitivity to the direction of the magnetostatic field and the bandwidth of a stopband. Furthermore, the effects of metasurface geometry and biasing field can be considered separately for initial design purposes. All features in the transmittance spectra for the bias‐free configuration that are related to the number of cascaded metasurfaces are also observed when the biasing magnetostatic field is applied. The coupling of adjacent metasurfaces in a cascade is strongly affected by the relative permittivity and the thickness of the spacer between the two metasurfaces. The spectral locations of stopbands scale with respect to the spacer's relative permittivity, the scaling rule being different from a classical one. The stopbands are redshifted when the spacer thickness is increased, with the redshift dependent on the polarization of the incident plane wave. Inter‐metasurface coupling and inter‐resonator coupling on the same metasurface affect the spectral location of a stopband in opposite ways. On‐off type switching can be obtained by changing the orientation of magnetostatic field. The elucidated characteristics are expected to be important for not only filters but also other tunable THz devices.
Organocatalyzed Photocontrolled Radical Polymerization of Semifluorinated (Meth)acrylates Driven by Visible Light
Authors: Gong Honghong , Zhao Yucheng , Shen Xianwang , Lin Jun , Chen Mao 
Published: November 2017

AbstractFluorinated polymers are important materials that are widely used in many areas. Herein, we report the development of a metal‐free photocontrolled radical polymerization of semifluorinated (meth)acrylates with a new visible‐light‐absorbing organocatalyst. This method enabled the production of a variety of semifluorinated polymers with narrow molar‐weight distributions from semifluorinated trithiocarbonates or perfluoroalkyl iodides. The high performance of “ON/OFF” control and chain‐extension experiments further demonstrate the utility and reliability of this method. Furthermore, to streamline the preparation of semifluorinated polymers, a scalable continuous‐flow approach has been developed. Given the broad interest in fluorinated materials and photopolymerization, we expect that this method will facilitate the development of advanced materials with unique properties.
Internal Peptide Late‐Stage Diversification: Peptide‐Isosteric Triazoles for Primary and Secondary C(sp3)−H Activation
Authors: Bauer Michaela , Wang Wei , Lorion Mélanie M. , Dong Chuan , Ackermann Lutz 
Published: November 2017

AbstractSecondary C(sp3)−H arylations were accomplished by palladium catalysis with triazoles as peptide bond isosteres. The unique power of this approach is highlighted by the possibility of achieving secondary C(sp3)−H functionalizations on terminal peptides as well as the unprecedented positional‐selective C(sp3)−H functionalization of internal peptide positions, setting the stage for modular peptide late‐stage diversification.
Synthesis and properties of non‐cytotoxic poly(l‐malic acid acetate‐co‐l‐lysine ester)s with thermo‐sensitivity as hydrophobic drug nanocarrier
Authors: Yue Ying , Fan Zhihui , Zheng Chang , Ding Lan , Wang Huiying , Zhang Miao , Deng Kuilin 
Published: November 2017

ABSTRACTIn this investigation, a group of poly(l‐malic acid acetate‐co‐l‐lysine ester)s (PMALs) with excellent thermo‐sensitivity and non‐cytotoxicity were prepared by an optimized synthetic route from natural l‐malic acid and l‐lysine. The structure and properties of PMALs including monomers were systematically characterized by FTIR, 1H NMR, UV, gel permeation chromatograph, scanning electron microscope, contact angle measurement, cell counting kit assess (CCK‐8), and confocal laser scanning microscopy (CLSM). Three PMALs show a reversible lower critical solution temperature of 8–36 °C depending on their chemical structure. The contact angle measurement revealed a considerable discrepancy in the hydrophilicity/hydrophobicity of PMALs and further influence on their thermo‐sensitivity. The viability of HeLa cells exposed to 0.2–100 μg/mL PMALs solution was found to be in a range 80–103% after 24, 48, and 72 h of incubation, indicating no cytotoxicity. Moreover, a spherical nanocarrier with core‐shell structure was facilely fabricated via the thermo‐sensitivity of PMALs and hydrophobicity of drug. CLSM observations manifested that the hydrophobic‐curcumin‐enwrapped nanocarriers can clearly internalize into the cellular inside. The sustained release of curcumin from nanocarriers in vitro provided a possibility of depressing fast hydrolytic degradation at physiological pH or other side‐effects. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45984.
Alkylation of Ketones Catalyzed by Bifunctional Iron Complexes: From Mechanistic Understanding to Application
Authors: Seck Charlotte , Mbaye Mbaye Diagne , Coufourier Sébastien , Lator Alexis , Lohier Jean‐François , Poater Albert , Ward Thomas R. , Gaillard Sylvain , Renaud Jean‐Luc 
Published: November 2017

AbstractCyclopentadienone iron dicarbonyl complexes were applied in the alkylation of ketones with various aliphatic and aromatic ketones and alcohols via the borrowing hydrogen strategy in mild reaction conditions. DFT calculations and experimental works highlight the role of the transition metal Lewis pairs and the base. These iron complexes demonstrated a broad applicability in mild conditions and extended the scope of substrates.
The Intermetalloid Cluster Cation (CuBi8)3+
Authors: Knies Maximilian , Kaiser Martin , Isaeva Anna , Müller Ulrike , Doert Thomas , Ruck Michael 
Published: November 2017

AbstractInvited for the cover of this issue is the group of Michael Ruck at the Technical University in Dresden. The image depicts the intermetalloid cluster (CuBi8)3+, which features a hitherto unknown bonding mode between bismuth and copper, and crystallizes as an adduct with an [AlCl4]− ion of the applied ionic liquid. Read the full text of the article at 10.1002/chem.201703916.