bluuebunny/crossref_metadata_2025_split huggingface dataset:
An integrated Pan-European perspective on coastal Lagoons management through a mosaic-DPSIR approach
Authors: Dolbeth Marina , Stålnacke Per , Alves Fátima L. , Sousa Lisa P. , Gooch Geoffrey D. , Khokhlov Valeriy , Tuchkovenko Yurii , Lloret Javier , Bielecka Małgorzata , Różyński Grzegorz , Soares João A. , Baggett Susan , Margonski Piotr , Chubarenko Boris V. , Lillebø Ana I. 
Published: January 2016

AbstractA decision support framework for the management of lagoon ecosystems was tested using four European Lagoons: Ria de Aveiro (Portugal), Mar Menor (Spain), Tyligulskyi Liman (Ukraine) and Vistula Lagoon (Poland/Russia). Our aim was to formulate integrated management recommendations for European lagoons. To achieve this we followed a DPSIR (Drivers-Pressures-State Change-Impacts-Responses) approach, with focus on integrating aspects of human wellbeing, welfare and ecosystem sustainability. The most important drivers in each lagoon were identified, based on information gathered from the lagoons’ stakeholders, complemented by scientific knowledge on each lagoon as seen from a land-sea perspective. The DPSIR cycles for each driver were combined into a mosaic-DPSIR conceptual model to examine the interdependency between the multiple and interacting uses of the lagoon. This framework emphasizes the common links, but also the specificities of responses to drivers and the ecosystem services provided. The information collected was used to formulate recommendations for the sustainable management of lagoons within a Pan-European context. Several common management recommendations were proposed, but specificities were also identified. The study synthesizes the present conditions for the management of lagoons, thus analysing and examining the activities that might be developed in different scenarios, scenarios which facilitate ecosystem protection without compromising future generations.
Carbon incorporation effects and reaction mechanism of FeOCl cathode materials for chloride ion batteries
Authors: Zhao Xiangyu , Li Qiang , Yu Tingting , Yang Meng , Fink Karin , Shen Xiaodong 
Published: January 2016

AbstractMetal oxychlorides are proved to be new cathode materials for chloride ion batteries. However, this kind of cathode materials is still in a very early stage of research and development. The obtained reversible capacity is low and the electrochemical reaction mechanism concerning chloride ion transfer is not clear. Herein, we report FeOCl/carbon composites prepared by mechanical milling of the as-prepared FeOCl with carbon nanotube, carbon black or graphene nanoplatelets as cathode materials for chloride ion batteries. The electrochemical performance of the FeOCl electrode is evidently improved by the incorporation of graphene into the cathode. FeOCl/graphene cathode shows a high reversible capacity of 184 mAh g−1 based on the phase transformation between FeOCl and FeO. Two stages of this phase transformation are observed for the FeOCl cathode. New insight into the reaction mechanism of chloride ion dissociation of FeOCl is investigated by DFT + U + D2 calculations.
Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice
Authors: Watari Kosuke , Shibata Tomohiro , Nabeshima Hiroshi , Shinoda Ai , Fukunaga Yuichi , Kawahara Akihiko , Karasuyama Kazuyuki , Fukushi Jun-ichi , Iwamoto Yukihide , Kuwano Michihiko , Ono Mayumi 
Published: January 2016

AbstractN-myc downstream regulated gene 1 (NDRG1) is a responsible gene for a hereditary motor and sensory neuropathy-Lom (Charcot–Marie–Tooth disease type 4D). This is the first study aiming to assess the contribution of NDRG1 to differentiation of macrophage lineage cells, which has important implications for bone remodeling and inflammatory angiogenesis. Ndrg1 knockout (KO) mice exhibited abnormal curvature of the spine, high trabecular bone mass and reduced number of osteoclasts. We observed that serum levels of macrophage colony-stimulating factor (M-CSF) and macrophage-related cytokines were markedly decreased in KO mice. Differentiation of bone marrow (BM) cells into osteoclasts, M1/M2-type macrophages and dendritic cells was all impaired. Furthermore, KO mice also showed reduced tumor growth and angiogenesis by cancer cells, accompanied by decreased infiltration of tumor-associated macrophages. The transfer of BM-derived macrophages from KO mice into BM-eradicated wild type (WT) mice induced much less tumor angiogenesis than observed in WT mice. Angiogenesis in corneas in response to inflammatory stimuli was also suppressed with decreased infiltration of macrophages. Taken together, these results indicate that NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.
Vertical La0.7Ca0.3MnO3 nanorods tailored by high magnetic field assisted pulsed laser deposition
Authors: Zhang Kejun , Dai Jianming , Zhu Xuebin , Zhu Xiaoguang , Zuo Xuzhong , Zhang Peng , Hu Ling , Lu Wenjian , Song Wenhai , Sheng Zhigao , Wu Wenbin , Sun Yuping , Du Youwei 
Published: January 2016

AbstractLa0.7Ca0.3MnO3 (LCMO) thin films on (LaAlO3)0.3(Sr2AlTaO6)0.7 (001) [LSAT (001)] single crystal substrates have been prepared by high magnetic field assisted pulsed laser deposition (HMF-PLD) developed by ourselves. Uniformly sized and vertically aligned nanorod structures can be obtained under an applied high magnetic field above 5 T and the dimension size of the nanorods can be manipulated by varying the applied magnetic field. It is found that the magnetic anisotropy is strongly correlated to the dimension size of the nanorods. A significantly enhanced low-field magnetoresistance (LFMR) of −36% under 0.5 T at 100 K can be obtained due to the enhanced carrier scattering at the vertical grain boundaries between the nanorods for the LCMO films. The growth mechanism of the nanorods has been also discussed, which can be attributed to the variation of deposition rate, adatom surface diffusion and nucleation induced by the application of a high magnetic field in the film processing. The successful achievements of such vertical nanorod structures will provide an instructive route to investigate the physical nature of these nanostructures and achieve nanodevice manipulation.
Aligned silver nanowire-based transparent electrodes for engineering polarisation-selective optoelectronics
Authors: Park Byoungchoo , Bae In-Gon , Huh Yoon Ho 
Published: January 2016

AbstractWe herein report on a remarkably simple, fast and economic way of fabricating homogeneous and well oriented silver nanowires (AgNWs) that exhibit strong in-plane electrical and optical anisotropies. Using a small quantity of AgNW suspension, the horizontal-dip (H-dip) coating method was applied, in which highly oriented AgNWs were deposited unidirectionally along the direction of coating over centimetre-scale lengths very rapidly. In applying the H-dip-coating method, we adjusted the shear strain rate of the capillary flow in the Landau-Levich meniscus of the AgNW suspension, which induced a high degree of uniaxial orientational ordering (0.37–0.43) of the AgNWs, comparable with the ordering seen in archetypal nematic liquid crystal (LC) materials. These AgNWs could be used to fabricate not only transparent electrodes, but also LC-alignment electrodes for LC devices and/or polarising electrodes for organic photovoltaic devices, having the potential to revolutionise the architectures of a number of polarisation-selective opto-electronic devices for use in printed/organic electronics.
The effects of organic solvents on the folding pathway and associated thermodynamics of proteins: a microscopic view
Authors: Yu Yuqi , Wang Jinan , Shao Qiang , Shi Jiye , Zhu Weiliang 
Published: January 2016

AbstractProtein folding is subject to the effects of solvation environment. A variety of organic solvents are used as additives for in vitro refolding of denatured proteins. Examination of the solvent effects on protein folding could be of fundamental importance to understand the molecular interactions in determining protein structure. This article investigated the folding of α-helix and β-hairpin structures in water and the solutions of two representative refolding additives (methanol (MeOH) and 1-Ethyl-3-methylimidazolium chloride (EMIM-Cl) ionic liquid) using REMD simulations. For both α-helix and β-hairpin in MeOH/water solution or α-helix in EMIM-Cl/water solution, the transient structures along the folding pathway are consistent with the counterparts in water but the relative statistical weights are changed, leading to the decrease in the overall folding free energy barrier. Accordingly, MeOH promotes the folding of both α-helix and β-hairpin but EMIM-Cl ionic liquid only promotes the folding of α-helix, consistent with experimental observations. The present study reveals for the first time the trivial effects on folding route but significant effects on folding thermodynamics from MeOH and EMIM-Cl, explaining the function of protein refolding additives and testifying the validity of the folding mechanism revealed by in vitro protein folding study using refolding additives.
Structure of the transmembrane domain of human nicastrin-a component of γ-secretase
Authors: Li Yan , Liew Lynette Sin Yee , Li Qingxin , Kang CongBao 
Published: January 2016

AbstractNicastrin is the largest component of γ-secretase that is an intramembrane protease important in the development of Alzheimer’s disease. Nicastrin contains a large extracellular domain, a single transmembrane (TM) domain and a short C-terminus. Its TM domain is important for the γ-secretase complex formation. Here we report nuclear magnetic resonance (NMR) studies of the TM and C-terminal regions of human nicastrin in both sodium dodecyl sulfate (SDS) and dodecylphosphocholine (DPC) micelles. Structural study and dynamic analysis reveal that the TM domain is largely helical and stable under both SDS and DPC micelles with its N-terminal region undergoing intermediate time scale motion. The TM helix contains a hydrophilic patch that is important for TM-TM interactions. The short C-terminus is not structured in solution and a region formed by residues V697-A702 interacts with the membrane, suggesting that these residues may play a role in the γ-secretase complex formation. Our study provides structural insight into the function of the nicastrin TM domain and the C-terminus in γ-secretase complex.
Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator
Authors: Yin Tao , Wang Guoping , Ye Tinghong , Wang Yongsheng 
Published: January 2016

AbstractThe cooperation of adaptive immunity with pharmacologic therapy influences cancer progression. Though non-steroidal anti-inflammatory drugs (NSAIDs) have a long history of cancer prevention, it is unclear whether adaptive immune system affects the action of those drugs. In present study, we revealed a novel immunological mechanism of sulindac. Our data showed that sulindac had substantial efficacy as a single agent against 4T1 murine breast cancer and prolonged the survival of tumor-bearing mice. However, in the athymic nude mice, sulindac treatment was ineffective. Further in vivo T cell subsets depletion experiments showed that CD8+ T lymphocytes deficiency reversed the anti-tumor effect of sulindac. In addition, sulindac significantly reduced M2 macrophages recruitment, cancer-related inflammation and tumor angiogenesis. Our results advance our understanding of the mechanisms of NSAIDs and more importantly, this will provide insight into rational drug design or antitumor immunotherapy.
Stable multilineage xenogeneic replacement of definitive hematopoiesis in adult zebrafish
Authors: Hess Isabell , Boehm Thomas 
Published: January 2016

AbstractBony fishes are the most numerous and phenotypically diverse group of vertebrates inhabiting our planet, making them an ideal target for identifying general principles of tissue development and function. However, lack of suitable experimental platforms prevents the exploitation of this rich source of natural phenotypic variation. Here, we use a zebrafish strain lacking definitive hematopoiesis for interspecific analysis of hematopoietic cell development. Without conditioning prior to transplantation, hematopoietic progenitor cells from goldfish stably engraft in adult zebrafish homozygous for the c-mybI181N mutation. However, in competitive repopulation experiments, zebrafish hematopoietic cells exhibit an advantage over their goldfish counterparts, possibly owing to subtle species-specific functional differences in hematopoietic microenvironments resulting from over 100 million years of independent evolution. Thus, our unique animal model provides an unprecedented opportunity to genetically and functionally disentangle universal and species-specific contributions of the microenvironment to hematopoietic progenitor cell maintenance and development.
Simultaneously enhanced device efficiency, stabilized chromaticity of organic light emitting diodes with lambertian emission characteristic by random convex lenses
Authors: Lee Keunsoo , Lee Jonghee , Kim Eunhye , Lee Jeong-Ik , Cho Doo-Hee , Lim Jong Tae , Joo Chul Woong , Kim Joo Yeon , Yoo Seunghyup , Ju Byeong-Kwon , Moon Jaehyun 
Published: January 2016

Abstract
An optical functional film applicable to various lighting devices is demonstrated in this study. The phase separation of two immiscible polymers in a common solvent was used to fabricate the film. In this paper, a self-organized lens-like structure is realized in this manner with optical OLED functional film. For an OLED, there are a few optical drawbacks, including light confinement or viewing angle distortion. By applying the optical film to an OLED, the angular spectra distortion resulting from the designed organic stack which produced the highest efficiency was successfully stabilized, simultaneously enhancing the efficiency of the OLED. We prove the effect of the film on the efficiency of OLEDs through an optical simulation. With the capability to overcome the main drawbacks of OLEDs, we contend that the proposed film can be applied to various lighting devices.
Alice Perrers and the Goldsmiths’ Mistery: New Evidence Concerning the Identity of the Mistress of Edward III
Authors: Tompkins Laura 
Published: January 2016

Abstract
In the last ten years, Mark Ormrod has published two articles in which he revealed the discovery of new evidence regarding the origins of Alice Perrers, the notorious mistress of Edward III during the final years of his life. From this research two new facts emerged: first, that Alice had a brother named John Salisbury, and second, that before her relationship with the king she was married to a man named Janyn Perrers. However, many questions remained unanswered. This article now reveals further discoveries from the collections of the London Metropolitan Archives and the Goldsmiths’ Company, which shed new light on the identities of John and Janyn and the wider questions surrounding Alice’s birth and early life. Through a detailed study of Alice’s later life, it examines the consequences of these findings in terms of Alice’s relationship with the king, her commercial activity and property acquisitions, ultimately establishing a clear context for the behaviour for which she would be condemned as the mistress of Edward III.
Ideology, Careerism and Civic Consciousness: The Crusade against Basel, 1482–1485
Authors: Housley Norman 
Published: January 2016

Abstract
The abstract for your paper is included below. This will appear online only. In December 1482 Pope Sixtus IV gave his legate Angelo Geraldini the faculty to preach a crusade against the people of Basel for refusing to hand over the person of the Croatian Dominican Andrija Jamometić, whose appeal for a council had plunged Sixtus’s reign into crisis. This essay compares the various threads of thought and action which prompted the Pope to resort to the crusade and led Geraldini to make use of the faculty. It is argued that Jamometić’s rebellion was probably triggered by his acute discontent with the way Sixtus had managed the crusade against the Turks, most recently his duplicitous response to their landing at Otranto. A combination of triumphalist emphasis on papal authority and anxiety about a revival of conciliarism caused Sixtus to include crusade as one of the options given to Geraldini. The legate faced resistance at Basel but he was also frustrated by Sixtus’s practice of dispersing his delegated authority among a number of agents in the field; using the crusade faculty became the only way that Geraldini could assert his primacy and advance his own prospects. Basel’s opposition stemmed in part from the awareness of its ruling elite that Frederick III would have to shield it from the Pope and his agents in order to defend dynastic and imperial interests in south-western Germany. But it also sprang from growing coolness towards Rome, and this was evidenced by the undemanding terms imposed on Basel as the price for its readmission to the Catholic community in 1485.
The influence of health-specific social network site use on the psychological well-being of cancer-affected people
Authors: Erfani Seyedezahra Shadi , Blount Yvette , Abedin Babak 
Published: January 2016

Objective We aimed to explore and examine how and in what ways the use of social network sites (SNSs) can improve health outcomes, specifically better psychological well-being, for cancer-affected people.
Methods Qualitative semi-structured interviews were conducted with users of the Ovarian Cancer Australia Facebook page (OCA Facebook), the exemplar SNS used in this study. Twenty-five women affected by ovarian cancer who were users of OCA Facebook were interviewed. A multi-theory perspective was employed to interpret the data.
Results Most of the study participants used OCA Facebook daily. Some users were passive and only observed created content, while other users actively posted content and communicated with other members. Analysis showed that the use of this SNS enhanced social support for users, improved the users’ experiences of social connectedness, and helped users learn and develop social presence, which ultimately improved their psychological well-being.
Discussion The strong theoretical underpinning of our research and empirically derived results led to a new understanding of the capacity of SNSs to improve psychological well-being. Our study provides evidence showing how the integration of these tools into existing health services can enhance patients’ psychological well-being. This study also contributes to the body of knowledge on the implications of SNS use for improving the psychological well-being of cancer-affected people.
Conclusion This research assessed the relationship between the use of SNSs, specifically OCA Facebook, and the psychological well-being of cancer-affected people. The study confirmed that using OCA Facebook can improve psychological well-being by demonstrating the potential value of SNSs as a support service in the healthcare industry.
Printed HF antennas for RFID on-metal transponders
Authors: Janeczek Kamil , Arazna Aneta , Salski Bartłomiej , Lipiec Krzysztof , Jakubowska Małgorzata 
Published: January 2016

Purpose– The purpose of this paper is to investigate screen-printed high-frequency (HF) antennas for radio frequency identification (RFID) on-metal transponders in which a magnetic sheet was used as a substrate material.Design/methodology/approach– A transponder antenna was designed in the form of square coil using a high-frequency electromagnetic software. Then, the antenna was fabricated with screen printing technique on two different magnetic sheets (RFN4 and RFN7) and on polyethylene naphthalate (PEN) foil for comparison. Its printing was carried out with polymer pastes based on silver flakes (PM-406 and SF). Thickness, track width and spacing were examined for the antennas using digital microscope and contact profilometer. Resistance and inductance were also measured, and resonant frequency, quality factor and target values of capacitance to achieve resonant frequency of the tested antenna at 13.56 MHz were calculated. Finally, RFID chips were mounted to the prepared antennas using an isotropic conductive adhesive, and a maximum read distance was measured with a reader installed in a smartphone.Findings– It was found that an antenna thickness on the magnetic sheets used was higher than on PEN foil. At the same time, surface roughness of the fabricated antennas on these sheets was revealed to be higher as well. Inductance of the measured antennas exhibited good conformity with the antenna design, but higher divergence was noticed in the measured resistance. Its lowest value was achieved when the antenna was printed with the paste PM-406 on PEN foil and the highest one when it was fabricated with the paste SF on the same substrate. This suggests that high attention needs to be paid to a polymer paste selected for antenna printing. The performed tests showed that the magnetic sheet RFN4 seems to be better substrate for on-metal transponders compared to RFN7 due to lower resistance and higher quality factor of the prepared antennas.Research limitations/implications– Further investigations are required to examine mechanical and thermal durability of the HF antennas printed on the magnetic sheets.Practical implications– The investigated HF antennas fabricated on magnetic sheets can find application in near field communication (NFC) transponders designed to be placed on metallic surfaces, e.g. on frames of advertising screens.Originality/value– Influence of used magnetic sheets and polymer pastes on geometry and electrical properties of HF antennas for RFID on-metal transponders was investigated. The presented investigations can be interesting for NFC/RFID designers who are involved in designing systems suitable for metallic surfaces.
Thermal properties of modified carbon films
Authors: Kalenik Jerzy , Kielbasinski Konrad , Firek Piotr , Czerwosz Elżbieta , Szmidt Jan 
Published: January 2016

Purpose– The purpose of this paper is to present thermal properties of palladium-carbon films prepared by physical vapour deposition (PVD)/chemical vapour deposition (CVD) methods.Design/methodology/approach– Thin palladium-carbon films were prepared at Tele- and Radioresearch Institute. Test structures containing palladium-carbon films and titanium electrodes were made. Temperature-resistance characteristics were measured.Findings– The results show strong temperature dependence of modified carbon film resistance. The dependence is stable, and so modified carbon films can be applied for various electronic applications.Originality/value– The paper presents thermal properties of thin palladium-carbon prepared by original PVD/CVD method at Tele- and Radioresearch Institute.