bluuebunny/crossref_metadata_2025_split huggingface dataset:
Follow-Up on 107 Fetuses with Normal Us + Echo After 37TH Week of Gestation
Authors: Strzelecka Iwona , Michalska Eliza , Zych-Krekora Katarzyna , Respondek-Liberska Maria 
Published: January 2018

Abstract
Introduction: Echocardiography of the fetal heart is an ultrasound examination that allows the evaluation of the anatomical structure and cardiovascular system usually performed in first half of pregnancy. Material and methods: This work presents the data of 107 fetuses with normal heart anatomy (NHA) and normal heart study (NHS) and their neonatal follow-up. In this group (in an addition to routine prenatal work-up) has been performed also a echocardiography examination in the third trimester of pregnancy, after 37th week of gestation: 61% of pregnant women were referred to the prenatal cardiology center due to the presence of high-risk pregnancies and 39% were low-risk pregnancies. Results: In two cases episodes of fetal arrhythmias were present during obstetrical examinations. After birth in the study group of 107 fetuses, 72% of newborns left the hospital during the 4 days and 28% newborns stayed in the hospital for longer time. In 16 cases their stay was extended due to maternal reasons and in 14 for newborns reasons. Conclusions: 1) In the neonate group, after prenatal cardiac evaluation > the 37th week of gestation such as “ normal fetal heart anatomy & normal heart study”, all newborns in our center were born in good general condition. 2) Late prenatal echocardiography in 3rd trimester of pregnancy maybe considered as additional tool to prove fetal well being, specially in high risk pregnancies.
Fetal Macrosomia, Polyhydramnios and Cardiac Anomalies may be Helpful to Predict Poor Outcome in Neonate – Case Report of a Possible Fetal Rasopathy with Sonographic and Neonatal Findings and Genetic Evaluation.
Authors: Respondek-Liberska Maria , Węgrzynowski Jerzy , Oszukowski Przemysław , Gulczyńska Ewa , Nykiel Elżbieta , Jakubowski Lucjusz , Grzesiak Mariusz , Czichos Ewa , Romanowicz Hanna 
Published: January 2018

Abstract
This is a case report about very rare findings in 2nd half of pregnancy (after normal 1 trimester scan ) at 18th week of gestation fetal macrosomia was detected unrelated to maternal diabetes, and acceleration fetal growth later on with unusual cardiac abnormalities (fetal cardiomegaly, cardiomyopathy, partial abnormal venous connection ). Progressive features of congestive heart failure with polyhydramnios in a fetus with estimated 5500 g predicted a poor outcome and severe neonatal condition, which was presented and discussed with the parents to be. Casearean section was performed at 33rd weeks of gestation due to maternal dyscomfort, severe legs edema and her tachypnoe. Baby boy was delivered with birth weight of 5050g, Apgar 4 with mutiple tumors. Conservative care was introduced and neonated died on the 3rd day. Differential diagnosis was discussed with special attention to Costello syndrome however without proved by genetic make-up from neonatal blood.
Tests for comparison of multiple endpoints with application to omics data
Authors: Marozzi Marco 
Published: January 2018

Abstract
In biomedical research, multiple endpoints are commonly analyzed in “omics” fields like genomics, proteomics and metabolomics. Traditional methods designed for low-dimensional data either perform poorly or are not applicable when analyzing high-dimensional data whose dimension is generally similar to, or even much larger than, the number of subjects. The complex biochemical interplay between hundreds (or thousands) of endpoints is reflected by complex dependence relations. The aim of the paper is to propose tests that are very suitable for analyzing omics data because they do not require the normality assumption, are powerful also for small sample sizes, in the presence of complex dependence relations among endpoints, and when the number of endpoints is much larger than the number of subjects. Unbiasedness and consistency of the tests are proved and their size and power are assessed numerically. It is shown that the proposed approach based on the nonparametric combination of dependent interpoint distance tests is very effective. Applications to genomics and metabolomics are discussed.
Intermolecular Interactions of Pyridine in Liquid Phase and Aqueous Solution Studied by Soft X-ray Absorption Spectroscopy
Authors: Nagasaka Masanari , Yuzawa Hayato , Kosugi Nobuhiro 
Published: January 2018

Abstract
Intermolecular interactions of pyridine in liquid and in aqueous solution are studied by using soft X-ray absorption spectroscopy (XAS) at the C, N, and O K-edges. XAS of liquid pyridine shows that the N 1s→π* peak is blue shifted and the C 1s→π* peak of the meta and para sites is red shifted, respectively, as compared with XAS of pyridine gas. These shifts in liquid are smaller than those in clusters, indicating that the intermolecular interaction of liquid pyridine is weaker than that of pyridine cluster, as supported by the combination of quantum chemical calculations of the core excitation and molecular dynamics simulations of the liquid structure. On the other hand, XAS spectra of aqueous pyridine solutions (C5H5N)x(H2O)1−x
measured at different molar fractions show that in the pyridine rich region, x>0.7, the C and N 1s→π* peak energies are not so different from pure liquid pyridine (x=1.0). In this region, antiparallel displaced structures of pyridine molecules are dominant as in pure pyridine liquid. In the O K-edge XAS, the pre-edge peaks sensitive to the hydrogen bond (HB) network of water molecules show the red shift of −0.15 eV from that of bulk water, indicating that small water clusters with no large-scale HB network are formed in the gap space of structured pyridine molecules. In the water rich region, 0.7>x, the N 1s→π* peaks and the O 1s pre-edge peaks are blue shifted, and the C 1s→π* peaks of the meta and para sites are red-shifted by increasing molar fraction of water. The HB network of bulk water is dominant, but quantum chemical calculations indicate that small pyridine clusters with the HB interaction between the H atom in water and the N atom in pyridine are still existent even in very dilute pyridine solutions.
Maize Transposable Elements Ac/Ds as Insertion Mutagenesis Tools in Candida albicans
Authors: Mielich Kevin , Shtifman-Segal Ella , Golz Julia C , Zeng Guisheng , Wang Yue , Berman Judith , Kunze Reinhard 
Published: January 2018

Abstract
In nonmodel systems, genetic research is often limited by the lack of techniques for the generation and identification of gene mutations. One approach to overcome this bottleneck is the application of transposons for gene tagging. We have established a two-element transposon tagging system, based on the transposable elements Activator (Ac)/Dissociation (Ds) from maize, for in vivo insertion mutagenesis in the fungal human pathogen Candida albicans. A nonautonomous Ds transposon carrying a selectable marker was constructed into the ADE2 promoter on chromosome 3 and a codon usage-adapted Ac transposase gene was inserted into the neutral NEUT5L locus on chromosome 5. In C. albicans cells expressing the transposase, the Ds element efficiently excised and reintegrated elsewhere in the genome, which makes the Ac/Ds transposons promising tools for saturating insertion mutagenesis in clinical strains of C. albicans.
Genetic Loci Controlling Carotenoid Biosynthesis in Diverse Tropical Maize Lines
Authors: Azmach Girum , Menkir Abebe , Spillane Charles , Gedil Melaku 
Published: January 2018

AbstractThe discovery and use of genetic markers associated with carotenoid levels can help to exploit the genetic potential of maize for provitamin A accumulation more effectively. Provitamin A carotenoids are classes of carotenoids that are precursors of vitamin A, an essential micronutrient in humans. Vitamin A deficiency is a global public health problem affecting millions of people, especially in developing countries. Maize is one of the most important staple crops targeted for provitamin A biofortification to help alleviate vitamin A deficiency in developing countries. A genome-wide association study (GWAS) of maize endosperm carotenoids was conducted using a panel of 130 diverse yellow maize tropical inbred lines genotyped with Genotyping by Sequencing (GBS) SNP markers. Numerous significant association signals co-localizing with the known carotenoid biosynthesis genes crtRB1, lcyE and ZEP1 were identified. The GWAS confirmed previously reported large effects of the two major carotenoid biosynthesis genes lcyE and crtRB1. In addition, significant novel associations were detected for several transcription factors (e.g., RING zinc finger domain and HLH DNA-binding domain super family proteins) that may be involved in regulation of carotenoid biosynthesis in maize. When the GWAS was re-conducted by including the major effects of lcyE and crtRB1 genes as covariates, a SNP in a gene coding for an auxin response factor 20 transcription factor was identified which displayed an association with β-carotene and provitamin A levels. Our study provides a foundation for design and implementation of genomics-assisted selection strategies for provitamin A maize breeding in tropical regions, and advances efforts toward identification of additional genes (and allelic variants) involved in the regulation of carotenoid biosynthesis in plants.
Reducing Unnecessary Imaging and Pathology Tests: A Systematic Review
Authors: Hiscock Harriet , Neely Rachel Jane , Warren Hayley , Soon Jason , Georgiou Andrew 
Published: January 2018

CONTEXT:
Unnecessary imaging and pathology procedures represent low-value care and can harm children and the health care system.

OBJECTIVE:
To perform a systematic review of interventions designed to reduce unnecessary pediatric imaging and pathology testing.

DATA SOURCES:
We searched Medline, Embase, Cinahl, PubMed, Cochrane Library, and gray literature.

STUDY SELECTION:
Studies we included were: reports of interventions to reduce unnecessary imaging and pathology testing in pediatric populations; from developed countries; written in the English language; and published between January 1, 1996, and April 29, 2017.

DATA EXTRACTION:
Two researchers independently extracted data and assessed study quality using a Cochrane group risk of bias tool. Level of evidence was graded using the Oxford Centre for Evidence-Based Medicine grading system.

RESULTS:
We found 64 articles including 44 before-after, 14 interrupted time series, and 1 randomized controlled trial. More effective interventions were (1) multifaceted, with 3 components (mean relative reduction = 45.0%; SD = 28.3%) as opposed to 2 components (32.0% [30.3%]); or 1 component (28.6%, [34.9%]); (2) targeted toward families and clinicians compared with clinicians only (61.9% [34.3%] vs 30.0% [32.0%], respectively); and (3) targeted toward imaging (41.8% [38.4%]) or pathology testing only (48.8% [20.9%]), compared with both simultaneously (21.6% [29.2%]).

LIMITATIONS:
The studies we included were limited to the English language.

CONCLUSIONS:
Promising interventions include audit and feedback, system-based changes, and education. Future researchers should move beyond before-after designs to rigorously evaluate interventions. A relatively novel approach will be to include both clinicians and the families they manage in such interventions.
Bayesian Estimation for Inverse Weibull Distribution Under Progressive Type-II Censored Data With Beta-Binomial Removals
Authors: Vishwakarma Pradeep Kumar , Kaushik Arun , Pandey Aakriti , Singh Umesh , Singh Sanjay Kumar 
Published: January 2018

This paper deals with the estimation procedure for inverse Weibull distribution under progressive type-II censored samples when removals follow Beta-binomial probability law. To estimate the unknown parameters, the maximum likelihood and Bayes estimators are obtained under progressive censoring scheme mentioned above. Bayes estimates are obtained using Markov chain Monte Carlo (MCMC) technique considering square error loss function and compared with the corresponding MLE's. Further, the expected total time on test is obtained under considered censoring scheme. Finally, a real data set has been analysed to check the validity of the study.
A (des)proteção da força de trabalho no município de Parauapebas (PA)
Authors: Silva Andréa Ferreira Lima da , Mathis Adriana de Azevedo 
Published: January 2018

O estudo analisa a implementação e operacionalização das políticas públicas de segurança e saúde do trabalhador no município de Parauapebas-PA. O artigo aborda a formulação e execução das ações em saúde do trabalhador, considerando os Formuladores, representados na pesquisa pelo membro da OIT, empresa Vale S/A e sindicatos; os Executores, representados pelos gestores e trabalhadores dos serviços de segurança e saúde do trabalhador; e os Beneficiários, representados pelos trabalhadores da mineração. Conclui que a inoperância dessas políticas é determinada pela conjuntura política econômica do Brasil, mas também pela conjuntura local, onde se observa a ampliação do “exército industrial de reserva”, a primazia pela Saúde Suplementar, falta de controle social em saúde do trabalhador e a atuação neocorporativista dos sindicatos.
The Relationship of Wife's Attitude and Family Support towards Smoking Husband's Behavior inside the House in Ulee Susu, Darul Imarah Sub-District
Authors: . Ismail 
Published: January 2018

The society in Darul Kamal district in general and Ulee Susu settlements in particular work as farmers with low middle socioeconomic level. Data obtained from the Puskesmas Darul Imarah mentioned that respiratory tract diseases such as respiratory infection, Pneumonia, Bronchitis, TBC, etc always occupy as the highest percentage during the last three years. According to health officials, more than 60% of householders in the region are active smokers and some of them smoke Acehnese traditional cigarettes. The research method is analytic research with cross-sectional study approach, the population is husband who do smoke (both inside and outside the house) 1972 people. The sample is 106 people. The data analysis used to test the hypothesis is chi-square statistic test. The result of the study found that the majority of respondents strongly support her husband not to smoke in the house, is 63 respondents (59,4%), the majority of respondents have positive attitude in order to make the husband not smoking inside the house, is 56 respondents (52,8%), that her husband smokes inside the house, is 58 respondents (54.7%). It can be concluded that there is no relationship of wife attitude toward husband behavior smoking in the house (P.Value 0,95) and there is no relation of family support to husband behavior smoking in the house (P.Value 0,23).
Acculturation of Language and Culture among Native and Non Native Speakers of Togean in Togean Island Tojo Una Una Central Sulawesi Indonesia
Authors: M.Hum Prof. Dr. Hasanuddin, , M.Hum Prof. Dr. Moon Hidayati Otoluwa, 
Published: January 2018

The objectives of the research are (1) to find out the way of the two societies with different language and culture background assimilate together in the Togean Island, (2) to find out how to adapt their language and culture among Togean Society and the tourists in Togean island, (3) to find out the tolerance attitude exist among native people and the tourist in Togean Island, and (4) to find out the sympathy attitude between two groups with different language and culture background occur in Togean Island. The research used qualitative approach. The research findings were (1) Different language and culture background assimilation occurred when NS used a foreign language (English) to assimilate their language with NNS interaction. NS developed their language assimilation by using code switching and code mixing strategies. On the other hand, NNS also tried to acquire NS language; (2) Culture assimilation occurred in both NS and NNS when they were doing cultural practice, cultural activities, food selection, and interpersonal contact in both NS and NNS of Togean. (3) Language and culture adaptation of NS and NNS occurred at (a) intensive interaction with NS and NNS, (b) followed traditional habits of the NS, (c) eat rice for meals, (d) eat traditional foods, (e) participated in social activities, and (f) attending traditional activities. (4) Tolerance attitude between NS and NNS of Togean related to respects ethnics, ideology, accepted to other people, helpful, give appreciation, and permit among NS and NNS of Togean Islands. They have good tolerance attitude each other.Sympathy attitude is important unsure that should be done in interaction for make interaction running well, particularly for native speaker and non native speaker. In this research setting founded there are a lot of aspects that getting sympathy from native speaker and non native speaker. The aspect are language used, participated in traditional festival/ceremony, wear polite dress, followed the rule that made by native speaker, and many others. The significance of this research are:This research gives a good contribution for linguistic, especially the theory of antropolinguistics, sosiolinguistics, and psycholinguistics. It can be increased various theory of acculturation in language and culture in Indonesia. The research findings are significance for developing applied linguistics for teaching cross cultural understanding. It is also significance to give information for students and teacher in promoting their learning and teaching related to language and culture, tourism sectors in Togean Island.
Этимологическое гнездо *dati в праславянском языке: реконструкция, словообразование, семантика
Authors: Пятаева Наталия 
Published: January 2018

В статье представлены результаты изучения словарного корпуса индоевропейского корня *dō- в праславянском языке. В результате было выполнено следующее:
1) реконструировано этимологическое гнездо с вершиной *Dati ‘процесс передачи объекта другому лицу’ по отношению к праславянскому лингвохронологическому уровню на основе использования материалов этимологических словарей, включающих лексику позднепраславянского периода – «Этимологический словарь славянских языков» под редакцией О. Н. Трубачёва и «Słownik prasłowiański» под редакцией Ф. Славского;
2) дано описание методики реконструкции этимологического гнезда, построенного по типу словообразовательного гнезда, принципы составления и матрица лексикографического представления которого были разработаны А. Н. Тихоновым в «Словообразовательном словаре русского языка»;
3) представлена схема этимологического гнезда, на которой показаны последовательные словообразовательные и семантические отношения между родственными словами;
4) дано разноаспектное – семантическое, морфемное и морфологическое – описание корпуса слов, образующих этимологическое гнездо;
5) в реконструированном этимологическом гнезде выявлено 4 семантико-словообразовательных центра, которые деэтимологизировались на древнерусском лингвохронологическом уровне и образовали самостоятельные словообразовательные гнёзда: глагольное *dati, *damъ ‘давать’ и три именных – *danь ‘дань, подать как объект обязательной передачи в качестве выкупа, налога, дара’, *darъ ‘дар, подарок как объект добровольной передачи в качестве подарка, вознаграждения’ и существительное nomen acti *datja, обозначающее действие передачи дани, вручения подарка.
Автор надеется, что реконструированное в виде диахронического словообразовательного словаря этимологическое гнездо и разработанная схема (матрица) разноаспектного исследования и лексикографического представления крупных лексических объединений могут сыграть важную роль в системном описании динамики формирования картины мира носителей языка.
PENGARUH INFLASI, TINGKAT SUKU BUNGA, KURS, HARGA MINYAK DUNIA DAN HARGA EMAS DUNIATERHADAP IHSG DAN JIIDI BURSA EFEK INDONESIA
Authors: Sartika Umi 
Published: January 2018

The research aims to investigate empirically the influence of selected macroekonomic variables. The research design is associative. Independent variabel are inflation, Bank Indonesia certificate rate, the exchange rate of IDR, World Oil Price and World Gold Price on Indonesia Composite Index and Jakarta Islamic Index at The Indonesia Stock Exchange (IDX). This paper examines the direct effect of selected macroeconomic variabel on Indonesia Composite Indexand Jakarta Islamic Index.The data is taken from the monthly closing price of each dependent and independent variables. The sampling method used in this study is the sample saturated and obtained a sample of 60 months of data closing price. The data used are secondary data collection methods of data documentation. The analysis which used in this research is multiple linier regression analysis, F test and t test. The result of calculations using Eviews 8, showed that: the result hypothesis F test, obtained value of Fcompute > Ftable, means that there is the influence of inflation, Bank Indonesia certificate rate, the exchange rate of IDR, World Oil Price and World Gold Pricetogether on Indonesia Composite Index and Jakarta Islamic Index.While result of the hypothesis t test, showed that inflation, Bank Indonesia certificate rate, the exchange rate of IDR, World Oil Price and World Gold Price partially had not influence on Indonesia Composite Index and Jakarta Islamic Index
PENGARUH LINGKUNGAN KERJA, KETERLIBATAN KERJA DAN KOHESIVITAS DALAM KELOMPOK KERJA TERHADAP KINERJA KARYAWAN DENGAN ASPEK KEPUASAN KERJA SEBAGAI VARIABEL MEDIASI PADA KANTOR PELAYANAN PERBENDAHARAAN NEGARA (KPPN) PURWOREJO
Authors: Sulistyorini Eri 
Published: January 2018

The research is titled “Effect of Work Environment, Job Involvement and Cohesiveness within the Working Group on Employee Performance with Aspects of Job Satisfaction as a Mediating Variable in KPPN Purworejo”. The aims of research are to find out and to analyze the effect of work environment, job involvement and cohesiveness within the working group on employee performance with aspects of job satisfaction as a mediating variable. The method of research is survey with sampling technique uses non probability sampling by saturation sampling. Population from the research is all of employement KPPN Purworejo, it is known that sample size of this research is 35 respondents. Based on the result of research analysis data using Partial Least Square (PLS) indicated that :(1) Work Environment has positive and significant effect on employees job satisfaction KPPNPurworejo. (2) Work involvement has positive but no significant effect on employees job satisfaction KPPN Purworejo. (3) Group Cohesiveness has positive and significant effect on employee job satisfaction KPPN Purworejo. (4) Group Cohesiveness has positive and significant effect on employee performance KPPN Purworedjo. (5) Job Satisfaction has positive and significant effect on employee performance KPPN Purworejo. (6) Cohesiveness in Group directly affect employee performance , but also indirect effect on employee performance with mediated Job Satisfaction . It turns out that the direct effect coefficient 0.398 is greater than the indirect effect is 0.150 . So the results of the above analysis it can be concluded that job satisfaction is only partially mediates the relationship between Group Cohesiveness in the Employee Performance .