bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organizing a Proficiency Testing Program on Stamp Impressions Examination in Accordance with ISO/IEC 17043 Requirements
Authors: Li Chi‐keung , Hui Janesse Wing‐sze , Pang Chi‐Ming 
Published: January 2018

AbstractStamps and stamp impressions examinations are based on matching defects and design details on the questioned and control samples. These examinations are routinely carried out by document examiners around the world. International proficiency tests for questioned documents examination have been available for decades while similar programs specifically focusing on stamp impressions examination are rare. This study reported a recent proficiency testing program on stamp impressions examination organized by an accredited provider in accordance with ISO/IEC 17043 requirements. Twenty‐four forensic laboratories registered for the program. Apart from giving details on the design and operation of the program, this study also aimed to provide the limitations and difficulties encountered in sample preparations, homogeneity, and stability tests of the testing materials. Various comments and feedbacks received from the participants, particularly in respect of examination approaches, challenges faced by the participants in forming conclusions and their suggestions for further improvement would be evaluated.
Use of olmesartan and enteropathy outcomes: a multi‐database study
Authors: Dong Y.‐H. , Jin Y. , Tsacogianis T. N. , He M. , Hsieh P.‐H. , Gagne J. J. 
Published: January 2018

SummaryBackgroundMultiple case reports suggest that olmesartan may be linked to sprue‐like enteropathy; however, few epidemiological studies have examined this association and results have been mixed.AimTo assess whether olmesartan is associated with a higher rate of enteropathy vs other angiotensin II receptor blockers (ARBs).MethodsWe conducted a cohort study among ARB initiators in 5 US claims databases representing different health insurance programmes. Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for enteropathy‐related outcomes, including coeliac disease, malabsorption, concomitant diagnoses of diarrhoea and weight loss, and non‐infectious enteropathy, comparing olmesartan initiators to initiators of other ARBs after propensity score (PS) matching.ResultsWe identified 1 928 469 eligible patients. The unadjusted incidence rates were 0.82, 1.41, 1.66 and 29.20 per 1000 person‐years for coeliac disease, malabsorption, concomitant diagnoses of diarrhoea and weight loss, and non‐infectious enteropathy respectively. HRs after PS matching comparing olmesartan to other ARBs were 1.21 (95% CI, 1.05‐1.40), 1.00 (95% CI, 0.88‐1.13), 1.22 (95% CI, 1.10‐1.36) and 1.04 (95% CI, 1.01‐1.07) for each outcome. HRs were larger for patients aged 65 years and older (eg for coeliac disease, 1.57 [95% CI, 1.20‐2.05]), for patients receiving treatment for more than 1 year (1.62 [95% CI, 1.24‐2.12]), and for patients receiving higher cumulative olmesartan doses (1.78 [95% CI, 1.33‐2.37]).ConclusionsThis large‐scale, multi‐database study found a higher rate of enteropathy in olmesartan initiators as compared to initiators of other ARBs, although the absolute incidence rate was low in both groups.
Sense and Sensitivity: A Response to the Commentary by Keller et al. (2018)
Authors: Mesman Judi 
Published: January 2018

This reply to the commentary by Keller et al. (2018) on the article “Universality Without Uniformity: A Culturally Inclusive Approach to Sensitive Responsiveness in Infant Caregiving” (Mesman et al., ) highlights key points of agreement emphasizing the sense of investing in synergies across research traditions. These include the importance of distinguishing between different parenting constructs, the need for more studies to test the presented theoretical assumptions, and the value of examining multiple caregiver sensitivity in relation to infants’ developing membership of a community. The only point of disagreement reflects the rigidity versus flexibility of the sensitivity construct. This reply argues that it is exactly the versatility of the sensitivity construct that makes it a valuable building block for bridges between fields.
The Myth of Universal Sensitive Responsiveness: Comment on Mesman et al. (2017)
Authors: Keller Heidi , Bard Kim , Morelli Gilda , Chaudhary Nandita , Vicedo Marga , Rosabal‐Coto Mariano , Scheidecker Gabriel , Murray Marjorie , Gottlieb Alma 
Published: January 2018

This article considers claims of Mesman et al. (2017) that sensitive responsiveness as defined by Ainsworth, while not uniformly expressed across cultural contexts, is universal. Evidence presented demonstrates that none of the components of sensitive responsiveness (i.e., which partner takes the lead, whose point of view is primary, and the turn‐taking structure of interactions) or warmth are universal. Mesman and colleagues’ proposal that sensitive responsiveness is “providing for infant needs” is critiqued. Constructs concerning caregiver quality must be embedded within a nexus of cultural logic, including caregiving practices, based on ecologically valid childrearing values and beliefs. Sensitive responsiveness, as defined by Mesman and attachment theorists, is not universal. Attachment theory and cultural or cross‐cultural psychology are not built on common ground.
Longitudinal analysis on the effect of insertion torque on delayed single implants: A 3‐year randomized clinical study
Authors: Marconcini Simone , Giammarinaro Enrica , Toti Paolo , Alfonsi Fortunato , Covani Ugo , Barone Antonio 
Published: January 2018

AbstractBackgroundImplant stability is commonly related to insertion torque. Recently, it has been suggested that higher insertion torque may lead to greater bone resorption.PurposeThe aim of the present randomized clinical study was to evaluate the role of different insertion torque values in terms of implant success, marginal bone loss, and facial soft tissues recession.Materials and MethodsPatients requiring a single dental implant were recruited and randomized to receive one of two implants with the same macro‐geometry but different cutting designs. First group consists of a 90 degrees cutting groove know as self‐tapping implant, and the second group known as Blossom™ cutting groove. (Intra‐Lock, Boca Raton, Florida). The insertion torque (IT) was assessed and two groups followed: high‐IT (≥50 Ncm) group and regular‐IT (<50 Ncm) group. After 3 months, all the implants were restored. At baseline, buccal bone thickness (BBT) was recorded. During the 3‐year survey, the following outcomes had been registered: implant failures and success, radiographic marginal bone level around dental implant (MBL) and facial soft tissue level (FSTL).ResultsA hundred and sixteen implants were placed in healed sites. The overall survival rate after 3 years was 96.5%. The Cumulative Success Rate was 91.3% for the High IT group and 98.2% for the Regular IT group. The mean marginal bone loss and facial soft tissue recession, at a 3‐year evaluation, were significantly greater for the High‐IT group and in the mandible than that reached in the Regular‐IT group and in the maxilla.ConclusionPresent findings showed that implants placed with higher insertion torque in mandible led to greater bone resorption and mucosal recession than that registered for implants placed with a regular IT. Moreover, sites with a thick buccal bone wall (≥1 mm) showed smaller recession at the facial soft tissue level after 3 years.
Extremely low‐frequency electromagnetic fields accelerates wound healing modulating MMP‐9 and inflammatory cytokines
Authors: Patruno A. , Ferrone A. , Costantini E. , Franceschelli S. , Pesce M. , Speranza L. , Amerio P. , D'Angelo C. , Felaco M. , Grilli A. , Reale M. 
Published: January 2018

AbstractObjectivesIn our previous reports, we have demonstrated that extremely low‐frequency electromagnetic fields (ELF‐EMF) exposure enhances the proliferation of keratinocyte. The present study aimed to clarify effects of ELF‐EMF on wound healing and molecular mechanisms involved, using a scratch in vitro model.Materials and methodsThe wounded monolayer cultures of human immortalized keratinocytes (HaCaT), at different ELF‐EMF and Sham exposure times were monitored under an inverted microscope. The production and expression of IL‐1β, TNF‐α, IL‐18 and IL‐18BP were measured by enzyme‐linked immunosorbent assay and quantitative real‐time PCR. The activity and the expression of matrix metalloproteinases (MMP)‐2/9 was evaluated by zymography and Western blot analysis, respectively. Signal transduction proteins expression (Akt and ERK) was measured by Western blot.ResultsThe results of wound healing in vitro assay revealed a significant reduction of cell‐free area time‐dependent in ELF‐EMF‐exposed cells compared to Sham condition. Gene expression and release of cytokines analysed were significantly increased in ELF‐EMF‐exposed cells. Our results further showed that ELF‐EMF exposure induced the activity and expressions of MMP‐9. Molecular data showed that effects of ELF‐EMF might be mediated via Akt and ERK signal pathway, as demonstrated using their specific inhibitors.ConclusionsOur results highlight ability of ELF‐EMF to modulate inflammation mediators and keratinocyte proliferation/migration, playing an important role in wound repair. The ELF‐EMF accelerates wound healing modulating expression of the MMP‐9 via Akt/ERK pathway.
The transient receptor potential vanilloid‐3 regulates hypoxia‐mediated pulmonary artery smooth muscle cells proliferation via PI3K/AKT signaling pathway
Authors: Zhang Qianlong , Cao Yonggang , Luo Qian , Wang Peng , Shi Pilong , Song Chao , E Mingyao , Ren Jing , Fu Bowen , Sun Hongli 
Published: January 2018

AbstractObjectvesTransient receptor potential vanilloid 3 (TRPV3) is a member of the TRP channels family of Ca2+‐permeant cation channels. In this study, we aim to investigate the role of TRPV3 in pulmonary vascular remodeling and PASMCs proliferation under hypoxia.Materials and methodsThe expression of TRPV3 was evaluated in patients with pulmonary arterial hypertension (PAH) and hypoxic rats, using hematoxylin and eosin (H&E) and immunohistochemistry. In vitro, MTT assay, flow cytometry, Western blotting and immunofluorescence were performed to investigate the effects of TRPV3 on proliferation of PASMCs.ResultsWe found that, in vivo, the expression of TRPV3 was increased in patients with PAH and hypoxic rats. Right ventricular hypertrophy measurements and pulmonary pathomorphology data show that the ratio of the heart weight/tibia length (HW/TL), the right ventricle/left ventricle plus septum (RV/LV+S) and the medial width of the pulmonary artery were increased in chronic hypoxic rats. Moreover, the expression of proliferating cell nuclear antigen (PCNA), Cyclin D, Cyclin E and Cyclin A, phospho‐CaMKII (p‐CaMKII) were induced by hypoxia. In vitro, we revealed that hypoxia promoted PASMCs viability, increased the expression of PCNA, Cyclin D, Cyclin E, Cyclin A p‐CaMKII, made more cells from G0/G1 phase to G2/M + S phase, enhanced the microtubule formation, and increased [Ca2+]i, which could be suppressed by Ruthenium Red, an inhibitor of TRPV3, and TRPV3 silencing has similar effects. Furthermore, the up‐regulated expression of PCNA, Cyclin D, Cyclin E and Cyclin A, the increased number of cells in G2/M and S phase, and the enhanced activation and expression of PI3K and AKT proteins induced by hypoxia and in presence of carvacrol (an agonist of TRPV3), was significantly attenuated by incubation of LY 294002, a specific inhibitor for PI3K/AKT.ConclusionsThese findings suggest that TRPV3 is involved in hypoxia‐induced pulmonary vascular remodeling and promotes proliferation of PASMCs and the effect is, at least in part, mediated via the PI3K/AKT pathway.
Transmission electron microscopic and optical spectroscopic studies of Ni2+/Yb3+/Er3+/Tm3+ doped dual‐phase glass‐ceramics
Authors: Gao Zhigang , Lu Xiaosong , Zhang Yindong , Guo Shu , Liu Yinyao , Sun Shiyu , He Fei , Yang Piaoping , Ren Jing , Yang Jun 
Published: January 2018

AbstractNi2+/Yb3+/Er3+/Tm3+ codoped transparent glass‐ceramics (GCs) containing both hexagonal β‐YF3 and spinel‐like γ‐Ga2O3 dual‐phase nanoparticles (NCs) are synthesized by melt‐quenching and subsequent heating procedures. Two techniques of transmission electron microscopy (TEM) nanoanalytics and optical spectroscopy are conjugated to understand the distribution of the rare‐earth ions (REs) and transition metals (TMs) in the nanostructured GCs. It is found that the REs are located predominantly in β‐YF3, whereas the TMs in γ‐Ga2O3 NCs. As a result, energy transfer (ET) between the REs and TMs is considerably suppressed due to the large spatial separation (> 3 nm), but it is enhanced between the REs partitioned in the β‐YF3 NCs. This has important implications for intended and demanding photoluminescence functions. For example, an ultrabroadband near‐infrared (NIR) emission in the wavelength region of 1000‐2000 nm covering the entire telecommunications window is observed for the first time. Meanwhile, intense upconversion (UC) emissions covering the 3 primary colors and locating in the first biological window can be also recorded under excitation by a single pump source at 980 nm.
Dispersion and densification of nano Si–(Al)–C powder with amorphous/nanocrystalline bimodal microstructure
Authors: Yoon Bola , Lee Sea‐Hoon , Feng Lun 
Published: January 2018

AbstractThe dispersion behavior and densification of nano Si–(Al)–C powder with amorphous/nanocrystalline bimodal microstructure were investigated. The Si–C powders synthesized by a mechanical alloying (MA) process had a near‐spherical shape with an average particle size of 170 nm. A solid loading of 62 vol% was achieved using polyethyleneimine (PEI) as a dispersant. The optimum dispersant amount was 1 wt% based on zeta potential, sedimentation, and viscosity analysis data. The high zeta potential value (73 mV) compared with that of the commercially available SiC (65 mV) was caused by modified surface properties and consequent promotion of the cationic dispersant adsorption. A Si–Al–C slurry containing 6.5 wt% of sintering additives with a solid loading of 60 vol% was also prepared. The relative density of the dried Si–Al–C slurry was 63.3% without additional compaction, which could be densified at 1650°C at a pressure of 20 MPa using a spark plasma sintering furnace.
Mn doping effects on electric properties of 0.93(Bi0.5Na0.5)TiO3‐0.07Ba(Ti0.945Zr0.055)O3 ceramics
Authors: Zhang Xingru , Jiang Guicheng , Guo Feifei , Liu Danqing , Zhang Shantao , Yang Bin , Cao Wenwu 
Published: January 2018

AbstractThe validity of Mn element on 0.93(Bi0.5Na0.5)TiO3‐0.07Ba(Ti0.945Zr0.055)O3 ceramics (BNT‐BZT‐xMn) is certified by doping. On account of multiple effects introduced by Mn, the appropriate Mn content facilitates property improvement effectively. Compared with pure BNT‐BZT, d33 of the component x = 0.25 increases about 8% up to 187 pC/N and Qm of the component x = 1 increases about 84% up to 197. Thermally stimulated depolarization currents (TSDC) measurement reveals Mn additive is helpful to pyroelectric properties as well. The Mn‐doped component x = 0.125 exhibits better pyroelectric performance at room temperature. Corresponding pyroelectric coefficient and the figures of merit reach up to 0.061 μC/(cm2 °C), Fi=217 pm/V, Fν = 0.023 m2/C, and Fd = 12.6 μPa−1/2, respectively, even superior to lead‐based ceramics. Similar pyroelectric advantage is also observed in the component x = 0.5 near depolarization temperature Td. Mn doping has slight harmful influence on the ferroelectric‐to‐relaxor transition temperature TF−R, as well as Td, but hardly shows restriction on application. These results confirm Mn doping is an available strategy to improve BNT‐based ceramics. Therefore, Mn‐doped BNT‐BZT ceramics will be excellent candidates in area of high‐power piezoelectric application and pyroelectric detectors.
Biosimilars: what the dermatologist should know
Authors: Yamauchi P. , Crowley J. , Kaur P. , Spelman L. , Warren R. 
Published: January 2018

AbstractBiosimilars are highly similar versions of approved branded biologics. In contrast to generics, which are identical copies of the originator medicines, biosimilars are considered unique but related molecules that differ from the originator reference product as well as from each other. Owing to the complexity of biologic medicines, such as therapeutic monoclonal antibodies, minor differences between biosimilars and the reference products are acceptable provided these differences do not result in any clinically meaningful differences in safety or efficacy. In addition, minor changes in structure and function may occur over time in originator biologic products as a result of alterations in production materials (e.g. cell lines), processes or conditions. The developmental process for biosimilars focuses on a ‘totality of evidence’ approach that emphasizes a stepwise investigational process, including comprehensive structural, functional, pharmacologic and clinical assessment for similarity. The goal of the phase 3 clinical development programme for a biosimilar is not to establish efficacy, per se, but to demonstrate that there are no clinically meaningful differences between the proposed biosimilar and the reference product. The requirement to show clinical similarity informs biosimilar study design, including the selection of the patient population, disease state (indication), study endpoints and statistical methods. Based on the clinical trial results in a representative patient population, results may be extrapolated to other indications provided scientific justification is demonstrated based on, among other things, similar mechanism of action in the extrapolated indications. This review presents the current state of knowledge with respect to biosimilars. We aim to provide the practising clinician with a working knowledge of biosimilars as well as provide some practical guidance on their use and potential benefits in treating dermatologic diseases.
COALITION FORMATION AND BARGAINING PROTOCOLS: A REVIEW OF THE LITERATURE
Authors: Rogna Marco 
Published: January 2018

AbstractThis paper offers a review of the vast literature regarding bargaining and coalition formation. This topic has been generally described as the attempt to provide strategic foundations to cooperative solution concepts. It can therefore be seen as the linking ring between the non‐cooperative and the cooperative game‐theoretic approach to coalition formation. Its central role in economic theory and its relatively long history that goes back to the Nash program have fostered a large academic production, including surveys. Nonetheless, this paper will focus on an aspect that is often neglected in the dedicated surveys: the specificities of the bargaining protocols leading to different outcomes. Although generally downgraded to the rank of details, the differences in bargaining protocols, even when minor, can cause significant changes in fundamental aspects such as the possibility to reach full cooperation, the distribution of final pay‐offs and the time taken to reach an agreement. Focused on externalities‐free games, therefore on bargaining protocols sustaining solution concepts for cooperative games in characteristic function form, the paper aims at providing a brief but exhaustive review of the topic that could result in a very useful tool for any researcher approaching the subject of coalitional bargaining.
Successful management of obstetric disseminated intravascular coagulation using a portable fibrinogen‐measuring device
Authors: Inoue Rie , Sumikura Hiroyuki , Kumagai Asako , Kato Noriko , Makino Shintaro , Itakura Atsuo 
Published: January 2018

AbstractThe importance of fibrinogen replacement therapy in obstetric disseminated intravascular coagulation is well recognized. However, fibrinogen measurement in conventional laboratories has been a time‐consuming task. Recently, a Japanese manufacturer developed a portable device that enables immediate fibrinogen measurement at the point of care. This report describes a case in which this device was used for the successful management of obstetric disseminated intravascular coagulation.
Gender roles, food system biodiversity, and food security in Indigenous Peoples' communities
Authors: Kuhnlein Harriet V. 
Published: January 2018

AbstractTraditional knowledge and practice of Indigenous Peoples related to their food use and well‐being is a wealth of information for academic study and for public health nutrition. Despite unique long‐evolved heritages of knowledge of ecosystem resources, Indigenous Peoples comprise 15% of the global poor, but only 5% of the world's population, and they experience poverty, discrimination, and poor nutritional health at far greater rates than mainstream populations in their nations of residence. These disparities are unacceptable in all human rights frameworks, and the call to alleviate them resonates through all human development programmes and the United Nations organizations. The scholars contributing to this special issue of Maternal and Child Nutrition describe how gender roles and the right to food for several cultures of Indigenous Peoples can be fostered to protect their unique foods and traditions, providing food sovereignty and food and nutrition security benefits, especially for women and children. Aspects of societal maternal or paternal lineality and locality, division of labour, spirituality and decision‐making are described. These factors structure the impact of gender roles with Indigenous worldviews on the dynamics of family food access, its availability and use, and the use of local food biodiversity. Cultures of Indigenous Peoples in Ecuador, Nigeria, Thailand, India, Canada, Japan, and Morocco are discussed. This publication is a work of the Task Force on Traditional, Indigenous and Cultural Food and Nutrition of the International Union of Nutritional Sciences.
Mothers' groups enrich diet and culture through promoting traditional Quichua foods
Authors: Roche Marion L. , Ambato Lorena , Sarsoza Julieta , Kuhnlein Harriet V. 
Published: January 2018

AbstractIndigenous Peoples in Latin America bear a disproportionate burden of undernutrition, yet traditional foods, including wild leafy greens, can contribute nutritional value to diets. As part of a community nutrition intervention using local foods in highland Tungurahua, Ecuador, mothers' groups promoted the consumption of wild leafy greens through community cooking clubs and recipe competitions at local fairs. The objective was to assess the social, cultural, and nutritional potential of a mothers' club intervention that promoted 2 indigenous greens (stinging nettle/Urtica dioica L. and round‐leaved dock/Rumex obtusifolius L.) into children's diets. Key informant interviews and focus groups were conducted with 54 mothers and 16 elders to identify perceptions of the intervention and traditional foods. Social and cultural dimensions were identified through content analysis. The nutritional contribution of the leafy greens was estimated through semiquantitative food frequency questionnaires conducted with 160 participant mothers and 98 mothers living in comparison communities who had not been exposed to the intervention. The use of local foods generated pride for mothers and elders. Nonfood uses of the nettle proved an initial barrier to acceptance; however, peer support within mothers' groups enabled increased consumption. The greens were estimated to contribute an additional 8% vitamin A, 7% iron, 12% vitamin C, and 27% folate to children's recommended dietary intakes. By promoting wild leafy greens, mothers' groups improved food security and the cultural and nutritional value of their diets. Additionally, mothers' cooking clubs increased self‐efficacy and cultural identity for Quichua women, offering a highly acceptable nutrition intervention model.