bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of simultaneous input-shaping-based SIRMs fuzzy control for double-pendulum-type overhead cranes
Authors: Qian D. , Tong S. , Yang B. , Lee S. 
Published: December 2015

Abstract
Overhead cranes are extensively employed but their performance suffers from the natural sway of payloads. Sometime, the sway exhibits double-pendulum motions. To suppress the motions, this paper investigates the design of simultaneous input-shaping-based fuzzy control for double-pendulum-type overhead cranes. The fuzzy control method is based on the single input-rule modules (SIRMs). Provided the all the system variables are measurable, the SIRMs fuzzy controller is designed at first. To improve the performance of the fuzzy controller, the simultaneous input shaper is adopted to shape the control command generated by the fuzzy controller. Compared with other two control methods, i.e., the SIRMs fuzzy control and the convolved input-shaping-based SIRMs fuzzy control, simulation results illustrate the feasibility, validity and robustness of the presented control method for the anti-swing control problem of double-pendulum-type overhead cranes.
Projection Methods for Ill-Posed Problems Revisited
Authors: Kindermann Stefan 
Published: December 2015

Abstract
We consider the discretization of least-squares problems for linear ill-posed operator equations in Hilbert spaces. The main subject of this article concerns conditions for convergence of the associated discretized minimum-norm least-squares solution to the exact solution using exact attainable data. The two cases of global convergence (convergence for all exact solutions) or local convergence (convergence for a specific exact solution) are investigated. We review the existing results and prove new equivalent conditions when the discretized solution always converges to the exact solution. An important tool is to recognize the discrete solution operator as an oblique projection. Hence, global convergence can be characterized by certain subspaces having uniformly bounded angles. We furthermore derive practically useful conditions when this holds and put them into the context of known results. For local convergence, we generalize results on the characterization of weak or strong convergence and state some new sufficient conditions. We furthermore provide an example of a bounded sequence of discretized solutions which does not converge at all, not even weakly.
Genetic variability of Scots pine (Pinus sylvestris L.) in maternal regions of provenance
Authors: Przybylski Paweł , Matras Jan , Sułkowska Małgorzata 
Published: December 2015

Abstract
The analysis of chosen selected Scots Pine (Pinus sylvestris L.), populations representing different seed regions: 107 (Międzyzdroje), 305 (Woziwoda), 206 (Strzałowo), 208 (Białowieża), 504 (Bolesławiec), 606 (Józefów) were performed using 10 isoensyme markers: Gdh (E.C.1.4.1.2), Sdh-A, Sdh-B (E.C.1.1.1.25), Pgd-B (E.C.1.1.1.44), Mdh-A, Mdh-C (E.C.1.1.1.37), Got-A, Got-B, Got-C (E.C.2.6.1.1), Dia-C (E.C.1.8.1.4). There were calculated following genetic parameters: allelic frequencies, observed and expected heterozygosities, and Wright’s fixation indexes. In populations, the results of analysis indicated presence of rare alleles. In all study populations, the average effective number of alleles per locus was 1.46 and was lower than expected number of alleles per locus of 1.93. The results for the effective number of alleles of the population per locus were as follows: Strzałowo and Białowieża 1.54, Bolesławiec 1.48, Jozefów 1.44, Świnoujście 1.42, Woziwoda 1.35. Average observed heterozygosity in the studied populations was calculated at the level of 0.26 and it was lower than the expected heterozygosity at 0.28. For populations, the level of heterozygosities were as follow: Strzałowo 0.35, Bolesławiec and Białowieża 0.25, Józefów 0.27, Świnoujście 0.23, Woziwoda 0.26. In particular loci level of heterozygosity was different, as the most heterozygous Mdh-C locus was estimated, while minimum Got-C.
Significant differences in allele frequency of Hardy-Weinberg deviation equilibrium were found in 10 cases: Strzałowo (Got-C), Bolesławiec (Got-B), Białowieża (Got-B, Gdh), Józefów (Mdh-C), Międzyzdroje (Got-B, Got-C, Mdh-C), Woziwoda (Got-C, Gdh). All studied populations had a lower effective number of alleles per locus (Ne) comparing to the observed number of alleles (Na). Wright’s fixation indices were negative for populations: Strzałowo (-0.09), Józefów (-0.03), Międzyzdroje (-0.01) and positive for: Białowieża (0.12), Woziwoda and Bolesławiec (0.07). The extremely high Wright’s fixation index (0.12) was observed for Białowieża population.
Canopy recovery of pedunculate oak, Turkey oak and beech trees after severe defoliation by gypsy moth (Lymantria dispar): Case study from Western Hungary
Authors: Csóka György , Pödör Zoltán , Nagy Gyula , Hirka Anikó 
Published: December 2015

AbstractWe investigated the canopy recovery of 3 tree species (pedunculate oak, Turkey oak, European beech) at two locations in the Veszprém county (Western Hungary) after severe defoliation by gypsy moth caterpillars in the spring of 2005. The Turkey oak has evidently the best recovery potential, and it almost completely replaced the lost foliage in 4 months. The pedunculate oak and beech needed 2 years to reach the same level of recovery. The pedunculate oak suffered from a heavy infection ofMicrosphaera alphitoidesafter defoliation and it probably slowed down its recovery. Neither the presence ofAgrilus biguttatusin the oak plot nor the appearance ofAgrilus viridisin the beech plot was observed during the study period. Population density of the buprestidCoraebus floerentinusshowed a considerable increase in the oak plot, but remained under the damage level. Neither other harmful appearance of other pests nor significant tree mortality were observed within 4 years from the defoliation. These results provide information for the evaluation of longer term influences of the gypsy moth defoliation and may support the decisions concerning pest control.
Structure, development and health status of spruce forests affected by air pollution in the western Krkonoše Mts. in 1979–2014
Authors: Král Jan , Vacek Stanislav , Vacek Zdeněk , Putalová Tereza , Bulušek Daniel , Štefančík Igor 
Published: December 2015

Abstract
The structure and health status of waterlogged or peaty spruce (Picea abies [L.] Karst.) forests in the summit parts of the Krkonoše Mts. in the Czech Republic were studied in 1979–2014. The objective was to evaluate the stand structure, dead wood, trend of the health status and productivity on four permanent research plots (PRP) in relation to air pollution (SO2 and NOx concentrations) and climatic conditions (temperatures and precipitation amounts). Stand structure was evaluated on the base of the measured parameters of individual trees on PRP. The health status of trees was evaluated according to foliage, and their vitality was assessed according to their radial growth documented by dendrochronological analyses. The radial growth was negatively correlated with SO2 and NOx concentrations. Stand dynamics during the observation period was characterised by increased tree mortality, the presence of dead wood and reduction of stand density from 1983 to 1992, while the most severe impairment of health status and stand stability occurred in 1982–1987. The foliage mass of living trees has been gradually increasing since 1988, but no pronounced improvement of tree vitality was documented after the decrease in SO2 concentration. However, particularly physiologically weakened spruce trees were attacked by the European spruce bark beetle (Ips typographus). The process of forest damage is manifested not only by foliage reduction but also by symptoms of various necroses on the assimilatory organs. In terms of climatic data, the weather in April had the most important effect on radial growth. Diameter increment showed positive statistically significant correlation with temperature in growing season, but the precipitation effect was low.
Cambrian magmatism, Variscan high-grade metamorphism and imposed greenschist facies shearing in the Central Sredna Gora basement units (Bulgaria)
Authors: Lazarova Anna , Naydenov Kalin , Petrov Nikolai , Grozdev Valentin 
Published: December 2015

Abstract
Gneisses from the deep structural levels of the European Variscan Belt are well exposed in the Central Sredna Gora in Bulgaria. In general, migmatites predominate, but unmigmatized domains (or domains with incipient migmatization) are also documented in this area. This paper presents new structural, petrographic and U-Pb isotope geochronological data from such an unmigmatized part of the Variscan high-grade metamorphic basement (the Koprivshtitsa Unit). A predominant part of this unit represents an alternation of metagranitoids and metabasites. The protolith crystallization age of the metagranitoids is constrained at 491.5 ± 7.6 Ma by U-Pb laser ablation method on zircons. This age coincides with the previously available Late Cambrian protolith ages of metabasic rocks that crop out within the adjacent migmatitic unit. The Korpivshtitsa Unit comprises also lesser orthogneisses with Late Neoproterozoic protoliths. Based on the available local and regional paleogeographic reconstruction schemes, we suggest that the Upper Cambrian magmatic rocks intruded Upper Neoproterozoic crust during the initial opening stages of the Rheic Ocean or a related basin. Subsequently, both were involved in the Variscan high-grade deformation. The contact of the Koprivshitsa Unit with the migmatitic part of the metamorphic complex coincides with a north-vergent greenschist facies thrust zone – the Chuminska Shear Zone. The exact time of the shearing is still not well constrained but it clearly postdates the Variscan high-temperature metamorphism of the gneisses.
Orthopyroxene-enrichment in the lherzolite-websterite xenolith suite from Paleogene alkali basalts of the Poiana Ruscă Mountains (Romania)
Authors: Nédli Zsuzsanna , Szabó Csaba , Dégi Júlia 
Published: December 2015

Abstract
In this paper we present the petrography and geochemistry of a recently collected lherzolite-websterite xenolith series and of clinopyroxene xenocrysts, hosted in Upper Cretaceous–Paleogene basanites of Poiana Ruscă (Romania), whose xenoliths show notable orthopyroxene-enrichment. In the series a slightly deformed porphyroclastic-equigranular textured series could represent the early mantle characteristics, and in many cases notable orthopyroxene growth and poikilitic texture formation was observed. The most abundant mantle lithology, Type A xenoliths have high Al and Na-contents but low mg# of the pyroxenes and low cr# of spinel suggesting a low degree (< 10 %) of mafic melt removal. They are also generally poor in overall REE-s (rare earth elements) and have flat REY (rare earth elements+ Y) patterns with slight LREE-depletion. The geochemistry of the Type A xenoliths and calculated melt composition in equilibrium with the xenolith clinopyroxenes suggests that the percolating melt causing the poikilitization can be linked to a mafic, Al-Na-rich, volatile-poor melt and show similarity with the Late Cretaceous–Paleogene (66–72 Ma) subduction-related andesitic magmatism of Poiana Ruscă. Type B xenoliths, with their slightly different chemistry, suggest that, after the ancient depletion, the mantle went through a slight metasomatic event. A subsequent passage of mafic melts in the mantle, with similar compositions to the older andesitic magmatism of Poiana Ruscă, is recorded in the pyroxenites (Fe-rich xenoliths), whereas the megacrysts seem to be cogenetic with the host basanite. The Poiana Ruscă xenoliths differ from the orthopyroxene-enriched mantle xenoliths described previously from the Carpathian-Pannonian Region and from the Dacia block.
Effects of teicoplanin on cell number of cultured cell lines
Authors: Kashkolinejad-Koohi Tahere , Saadat Iraj , Saadat Mostafa 
Published: December 2015

Abstract
Teicoplanin is a glycopeptide antibiotic with a wide variation in human serum half-life. It is also a valuable alternative of vancomycin. There is however no study on its effect on cultured cells. The aim of the present study was to test the effect of teicoplanin on cultured cell lines CHO, Jurkat E6.1 and MCF-7. The cultured cells were exposed to teicoplanin at final concentrations of 0–11000 μg/ml for 24 hours. To determine cell viability, the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test was performed. At low concentrations of teicoplanin the numbers of cultured cells (due to cell proliferation) were increased in the three cell lines examined. The maximum cell proliferation rates were observed at concentrations of 1000, 400, and 200 μg/ml of teicoplanin for CHO, MCF-7 and Jurkat cell lines, respectively. Cell toxicity was observed at final concentrations over 2000, 6000, and 400 μg/ml of teicoplanin for CHO, MCF-7 and Jurkat cell lines, respectively. A dose-dependent manner of cell toxicity was observed. Our present findings indicated that teicoplanin at clinically used concentrations induced cell proliferation. It should therefore be used cautiously, particularly in children, pregnant women and patients with cancer.
Protective effect of Cupressus sempervirens extract against indomethacin-induced gastric ulcer in rats
Authors: Koriem Khaled M. M. , Gad Islam B. , Nasiry Zayenab K. 
Published: December 2015

Abstract

Cupressus sempervirens (C. sempervirens) belongs to the family Cupressaceae. It is widspread in Northern Africa, Greece, Turkey, North America, Cyprus and Syria. Cupressuflavone is the major ingredient of the plant leave extract. The aim of the present study was to evaluate the antiulcerogenic activity of the extract of C. sempervirens leaves in gastric ulcer tissues induced by indomethacin. The results of the present study revealed that indomethacin significantly decreased glutathione S-transferase (GST), glutathione peroxidase (GPx), catalase (CAT), reduced glutathione (GSH), glutathione reductase (GR) and superoxide dismutase (SOD) levels, while it increased significantly lipid peroxidation (MDA), nitric oxide (NO) and protein carbonyl (PC) levels in gastric tissue. Furthermore, indomethacin decreased p53 expression, while it increased bcl-2 expression in gastric tissue. Pretreatment with 5%, 10% & 20% of the LD50 of C. sempervirens and cupressuflavone of indomethacin-treated rats restored all the above parameters to approach normal values. C. sempervirens at the highest dose was more effective than the two lower doses. C. sempervirens proved more potent than cupressuflavone. In conclusion, C. sempervirens exerted antiulcerogenic activity and the effect was dose-dependent and related to the cupressuflavone ingredient of the plant leave extract.
Endothelium and the effect of activated neutrophils on arterial smooth muscle
Authors: Bauer Viktor , Sotnikova Ruzena 
Published: December 2015

Abstract
The aim of the study was to analyze the involvement of the endothelium in the effects of neutrophils (PMNL) on phenylephrine-pre-contracted isolated rings of the rat thoracic aorta and to compare their effects with those of peroxynitrite (ONOO−) and hypochlorous acid (HOCl). Activated PMNL-induced contraction of the precontracted aorta was prevented by the blockade of NO-synthase and by endothelium removal. In the endothelium-free preparations, the effect of PMNL reappeared in the presence of sodium nitroprusside. The effect of ONOO− and HOCl significantly differed from that of activated PMNL both in the presence and absence of the endothelium. It is therefore likely that neither ONOO− nor HOCl generated by transformation of superoxide anion radical (O2
•−) produced by PMNL is involved in their action. Reduction of the relaxant effect of nitric oxide derived from the endothelium by O2
•− seems to be the keystone mechanism in generation of PMNL-induced contraction.
Leptin And Ghrelin – The New Old Players In Obesity And Depression
Authors: Sandeva Rositsa V. , Mihaylova Stanislava M. , Sandeva Gergana N. 
Published: December 2015

Summary
The participation of the anorexigenic peptide leptin and the orexigenic peptide ghrelin in the pathogenesis of metabolic syndrome and obesity is well studied. In this review, we are taking a look at the structure, anatomical expression, regulation, receptors and physiological functions of these two neuropeptides. Leptin is produced almost exclusively in adipose tissue. It acts on the brain and is a key element in long-term regulation of energy balance. Leptin suppresses appetite and reduces body weight. Besides its central effects, important aspects of its action on peripheral tissues have been discovered recently: direct regulation of immune cells, pancreatic beta cells, adipocytes and muscle cells. Ghrelin is an endogenous ligand for the active form of the growth hormone receptor (GHS-R1a) and stimulates food intake and growth hormone secretion. We focus on the role of leptin and ghrelin in central nervous system neural mechanisms that are associated with depression. Studying new aspects of these two neuropeptides aims to expand our knowledge of the pathogenesis and therapeutic approaches to diseases with which they are associated: obesity, depression, type 2 diabetes, essential hypertension, and more.
Correlations Between Acute Ischemic Stroke And Its Associated Cardiovascular Diseases
Authors: Arabadzhieva Daniela Y. , Kaprelyan Ara G. , Slavov Zdravko D. , Georgieva Zhaneta T. , Tsukeva Aleksandra Zh. 
Published: December 2015

Summary
The objective of this study was to analyze the association between some cardiovascular diseases and acute ischemic stroke. A total of 258 acute ischemic stroke patients (mean age 70.59±7.22 years) were examined. The presence of eight cardiovascular diseases and pathological conditions was analyzed: arterial hypertension, hypertensive heart, atrial fibrillation, myocardial infarction, ischemic heart disease, effort angina pectoris, coronary atherosclerosis, and heart failure. Data were statistically processed by variation and correlation analysis. Most male and female patients presented with four accompanying cardiovascular diseases (27 or 20.93% and 31 or 24.03% of the cases, respectively). There were two groups of four variables each - with a relatively strong and a moderate, as well as with a weak correlation (r<0.4), to the presence of acute ischemic stroke in the corresponding patients. Ischemic heart disease was strongly associated with effort angina pectoris (r=0.667) and to a lesser extent - with coronary atherosclerosis (r=0.470), whereas myocardial infarction was associated with coronary atherosclerosis (r=0.604) and ischemic heart disease (r=0.378), respectively. Arterial hypertension was moderately related to hypertensive heart (r=0.300). In conclusion, there were relatively close associations between acute ischemic stroke and these heart diseases. These patients should strictly and regularly be followed up by general practitioners.
Occupational Risk And Health Status Of Workers In The Production Of Heat
Authors: Kuneva Tanja P. , Stoyneva Zlatka B. , Medjidieva Daniela G. , Apostolova Diana B. , Kuzmov Shiboy N. , Oncheva Gergina N. , Toncheva Reny T. , Boyadzhieva Vladimira V. , Bozhinova Kristina V. 
Published: December 2015

Summary
The health status of 1515 workers employed in heat production was investigated. The subjects studied were divided in four groups according to occupation and occupational risk factors: vibration, noise, dust, metal aerosols, overloading of the musculoskeletal and peripheral nervous system, and organic solvents. The control group included 152 administrative staff members. High prevalence of socially significant diseases – cardiovascular, endocrine and metabolic was detected in all the groups surveyed. The frequency of diseases of the cardiovascular system and the respiratory system was 2.7 times higher than that in the control group. Statistically reliable higher prevalence of lung diseases in the studied risk groups was found, especially in the group of welders and chemists: 45.3% и 17.4% respectively, as compared to 4.3% in the controls. These finding corresponded to the occupational risk. The following occupation diseases were diagnosed: pneumoconiosis in 26.6% and toxic pneumofibrosis in 5.1% of electric welders. As regards the group of chemists, toxic pneumofibrosis was found in 6.5%. toxic effects of irritants - in 6.5 %, and chronic intoxication with organic radicals - in 0.7 % of them. Occupational auditory neuritis was diagnosed in 1% of the turbine operators and crane operators. The relative share of workers with peripheral nervous system pathology (radiculopathies, polyneuropathies, distal sympathetic neuropathy, mononeuropathy) was reliably higher than that in the control group, and the frequency increased among the workers with more than ten years of service and older than 40.
Experimental Study On The Development Of Tolerance And Withdrawal Syndrome To Pentylenetetrazole-Induced Seizures In Rats Treated With Retigabine
Authors: Apostolova Elisaveta G. , Kokova Vesela Y. , Peychev Lyudmil P. 
Published: December 2015

Summary
The aim of the study was to evaluate seizure liability in rats against the convulsant pentylenetetrazole (PTZ) during a 14-day treatment with retigabine (RTG). The seizure liability was also studied on the 1st, 2nd and 3rd day after the abrupt determination of its administration. Male Wistar rats were divided in groups of 10 and treated orally for 14 days (1st – 6th group with distilled water, and 7th – 12th group with retigabine (RTG) at a dose of 60 mg/kg bw The tolerance to the anticonvulsant effect of RTG was studied using subcutaneous injection of PTZ (120 mg/kg bw) on the 1th and 14th day. To determine the possible neuronal hyperexcitability on the 1st, 2nd and 3rd day after termination of drug administration, a lower dose of PTZ (65 mg/kg bw) was used. According to our results there was no change in the anticonvulsant activity of RTG during the whole period of treatment. The study on withdrawal syndrome showed slightly decrease of the effect on the first day after the last treatment, but with no significant difference to the controls. The anticonvulsant effect of RTG on the 2nd and 3rd day was close to that in the control group. Our results showed no development of tolerance on subchronic treatment with RTG. There was no significant change in the neuronal hyperexcitability on the 1st, 2nd and 3rd day after the termination of treatment. Based on these results we can suggest that RTG has no potential to develop withdrawal syndrome.
Translation, Adaptation And Validation Of The Bulgarian Version Of The SIDAED Questionnaire
Authors: Kuzmanova Rumyana N. , Stefanova Irina Z. , Velcheva Irena V. , Stambolieva Katerina I. 
Published: December 2015

Summary
The aim of the study is the translation, adaptation and validation of Side effects of antiepileptic drugs questionnaire in Bulgarian language (SIDAED-BG) in order to use it for objective monitoring of patients with epilepsy. One hundred and thirty one patients (mean age 40.13±13.37 years) took part in the investigation. The internal consistency and test-retest reliability were tested by Cronbach's α and ICC estimations. The convergent construct validity was evaluated by estimating the correlation of SIDAED-BG with the QOLIE-89 and the discriminant validity - by evaluation of the difference between SIDAED-BG scores and clinical parameters such as type of epilepsy using Kruskal-Wallis ANOVA. The Cronbach's α of the total scale was 0.93. The test-retest reliability was higher and determined the strong positive correlations between the first and second examination. The SIDAED-BG questionnaire showed good internal consistency (Cronbach's alpha ranged from 0.37 to 0.86) and the scores significantly correlated with other questionnaires such as QOLIE-89 and showed a good discriminative validity between groups with different levels of self-assessed adverse effects of antiepileptic drugs. The Bulgarian version of SIDAED is a reliable and valid tool in assessing the patient-reported adverse effects of antiepileptic drugs and their impact on the patient's outcome.