bluuebunny/crossref_metadata_2025_split huggingface dataset:
Grafitos de presos, de los siglos XVIII-XIX, en la Torre del Homenaje de la Alhambra
Authors: Barrera Maturana José Ignacio 
Published: December 2016

<p>In the Homage tower the Alhambra palace. The prisioners graffitis between XVIII-XIX centuries. </p><p>RESUMEN</p><p>Algunos autores han visto por la forma en que se dispone el recinto de La Alhambra en la colina de la Sabika, a un barco varado cuya proa es la Alcazaba. Es en esta proa y concretamente en el interior de la Torre del Homenaje, donde localizamos un numeroso grupo de grafitos, mayoritariamente barcos, que son objeto de nuestro estudio. Creemos que fueron realizados por presos, quizás algunos de ellos ingleses, alojados en este espacio durante los siglos XVIII-XIX.</p><p>PALABRAS CLAVE: Prisión, Torre del Homenaje, grafitos, barcos, pingue, presos ingleses, Isla de Menorca.</p><p>ABSTRACT</p><p>Some authors have seen by the way the grounds of the Alhambra is available in Sabika Hill, a stranded boat whose bow is the Alcazaba. It is in this bow and specifically in side of Homage Tower, where we located a large group of graffiti, mostly ships, which are the subject of our study. We believe they were made by prisoners, perhaps some of them British, housed in this space during the XVIII-XIX” centuries.</p><p>KEY WORDS: Prison, Homage Tower, graffiti, ships, pingue, British prisoners, Island of Minorca.</p>
La obra artística de Arcadio Blasco en Extremadura
Authors: Bazán de Huerta Moisés , Centellas Soler Miguel 
Published: December 2016

<p>Arcadio Blasco (1928-2013) es un polifacético artista con una trayectoria muy consolidada en el arte contemporáneo español. Destacan en ella los murales y esculturas cerámicas, con amplia proyección pública, y sus grandes vidrieras en colaboración con diversos arquitectos. Su estilo abstracto es muy innovador y creativo.</p><p>Hasta ahora no se había estudiado su valiosa aportación en Extremadura. Intervino en bastantes iglesias promovidas por el Instituto Nacional de Colonización, renovando la plástica religiosa de la zona. Para ellas creó murales cerámicos, mosaicos, pirograbados y vidrieras. Pero también tuvo encargos de colegios e instituciones públicas. El estudio analiza dichos trabajos y permite comprobar la versatilidad de su obra y su acusada personalidad, alternando la figuración con la abstracción.</p><p> </p>
El personaje de Grace en "Dogville" de Lars von Trier: continuidad y ruptura con los modelos de la tragedia clásica = The character of Grace in "Dogville" by Lars von Trier: continuity and breakup with the classic tragedy models
Authors: Breviatti Álvarez Jara 
Published: December 2016

<em><em></em></em>El propósito de este artículo es analizar el personaje de Grace en "Dogville" de Lars von Trier en relación<br />con las heroínas de la tragedia griega clásica. Desde esta perspectiva se observan las similitudes existentes<br />entre el personaje fílmico y los modelos clásicos al tiempo que se constatan las características<br />específicas y diferenciadoras de esta heroína moderna.<br /><br />The aim of this paper is to study the character of Grace in Lars von Trier’s Dogville in relation with the<br />heroines of Ancient Greek tragedy. From this perspective, the similarities between the filmic character<br />and the classic models are observed while the specific and distinctive characteristics of this modern<br />heroine are confirmed.<br />Key words: Dogville, Grace, women, Greek Tragedy<p> </p>
Ejercicios de caligrafía teatral para escribir una escena imprevisible y disconforme. Rodrigo García (1987-1997) = Theatrical calligraphy exercises to write an unpredictable and discordant scene. Rodrigo García (1987-1997)
Authors: Puchades Hernández Xavier 
Published: December 2016

<p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"> </p><p>Una etapa bastante desatendida en la trayectoria de Rodrigo García comprende desde su llegada a España hasta su incipiente proyección internacional. A partir de documentos de ese periodo, este estudio revisa sus primeras reflexiones teatrales, las diversas estrategias aplicadas a su escritura y puesta en escena, así como los referentes interdisciplinares que han ido conformando su universo escénico<strong>.</strong></p><p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"> </p><p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"> </p><p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"> </p><p>A stage rather neglected in Rodrigo García’s trajectory comprises from his arrival in Spain until his emerging international outreach. Using documents of that period, this research reviews his first theatrical reflections, the various strategies applied to his writing and staging, as well as interdisciplinary references that have shaped his scenic universe.</p><p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"> </p><p style="font-weight: normal; page-break-inside: avoid; widows: 136;" lang="es-ES" align="JUSTIFY"><span style="font-family: Book Antiqua,serif;"><span style="font-size: small;"><span style="font-family: Book Antiqua,serif;"><br /></span></span></span></p>
Potential Role of Liposomes for the Delivery of Phosphodiesterase Inhibitors to Erythrocytes for the Treatment of Type 2 Diabetes
Authors: Bowles Elizabeth A , Ercal Nuran , Sprague Randy S 
Published: December 2016

<p>Human erythrocytes participate in the regulation of vascular diameter in the microcirculation through the controlled release of the vasodilator adenosine triphosphate (ATP) in response to physiological stimuli, including exposure to low oxygen tension as occurs in the microcirculation of skeletal muscle. The localized release of this vasodilator has been suggested to be an important mechanism for matching perfusion (oxygen delivery) with need in this tissue. However, in certain diseases, such as type 2 diabetes (DM2), the ability of erythrocytes to release ATP in response to this stimulus is severely compromised. This defect in erythrocyte physiology could contribute to impairment of vasodilation in the peripheral circulation leading to vascular insufficiency and delayed wound healing. It has been shown that inhibitors of specific phosphodiesterases (PDEs) can augment low oxygen-induced ATP release from erythrocytes of humans with DM2. However, these drugs are associated with serious side effects that limit their use in clinical medicine. </p><p> Here we summarize the evidence in support of the hypothesis that delivery of PDE3 inhibitors encapsulated in liposomes to erythrocytes could provide a new approach for the treatment of DM2. In addition we report that inhibitors of PDE5 can also rescue low oxygen-induced ATP release from DM2 erythrocytes making this class of drugs another that could be targeted to erythrocytes. </p>
3D knee kinematics variability pre-operation versus post-operation in adolescence with Anterior Cruciate Ligament injury using functional principle component analysis
Authors: Ayoubian Leila 
Published: December 2016

<p><strong>Background: </strong>Anterior cruciate ligament (ACL) injuries in adolescents have increased in the past decade. The goal of ACL reconstructive surgery is to restore knee stability, however apart from subjective manual testing, there is no objective method to assess the impact of the treatment on knee stability. In clinical biomechanics, decreased variability in three dimensional (3D) kinematic angles can be associated with increased stability of the joint in performing a movement. Typically, the study of variability of 3D knee kinematics proceeds by reducing what are intrinsically functional responses to a single discrete measurement (e.g. peak flexion angle). As a result, many potentially informative data is ignored.<strong></strong></p><p><strong>Aim</strong>: Prospective gait variability analysis pre- and 6 months post- ACL reconstructive surgery in adolescence patients using Principle Component Analysis (FPCA). </p><p><strong>Method: </strong>FPCA is a multivariate statistical data analysis technique that focuses on treating an entire dataset as functions.<strong> </strong>Twenty eight ACL adolescent patients pre- and post-operation walked on a treadmill and the 3D knee kinematics were collected (flexion/extension, abduction/adduction and internal/external rotation angles). Functional Principle Component (FPCs) scores of the angle data were extracted to compare variability in gait. Repeated measures of ANOVA and box plots on FPC scores provided evidence of significant difference with decreased variability post-operation for both within-group and within-patients studies.</p><p><strong>Conclusion</strong>:</p><p>Variability in the 3D knee kinematics have been significantly reduced six months post- versus pre-operation. The proposed functional objective assessment method suggests that ACL reconstructive surgery increases joint stability during walking in adolescents.</p>
Postoperative Management of Crohn’s Disease: What Can We Do to Prevent Recurrence?
Authors: Olariu Adriana Georgiana , Bordeianou Liliana 
Published: December 2016

<p>Crohn’s disease (CD) is a chronic inflammatory bowel disease with a relapsing, remitting course. Approximately one in four CD patients requires surgery within five years of diagnosis. Unfortunately, surgery is rarely curative and up to 70% of CD patients experience endoscopic recurrence and 40% have clinical disease recurrence within 18 months after surgery.</p><p> </p><p>This review is aimed at providing internists and gastroenterologists a foundation for the management of patients who underwent ileocecal resection for CD. We provide an overview of the current definitions of postoperative recurrence and prognostic factors for postoperative CD recurrence. As recent studies raised concerns about the value of these factors, we examine the evidence behind the current risk stratification algorithm and pharmacologic treatment recommendations. Lastly, we discuss future directions for research.</p>
Using Dense SNPs and Large Families to Reduce Sequencing Costs
Authors: Stewart William 
Published: December 2016

<p>For modern linkage studies involving many small families, Stewart et al. (2009)[1] introduced an efficient estimator of disease gene location (denoted ) that averages location estimates from random subsamples of the dense SNP data. Their estimator has lower mean squared error than competing estimators and yields narrower confidence intervals (CIs) as well. However, when the number of families is small and the pedigree structure is large (possibly extended), the computational feasibility and statistical properties of are not known. We use simulation and real data to show that (1) for this extremely important but often overlooked study design, CIs based on are narrower than CIs based on a single subsample, and (2) the reduction in CI length is proportional to the square root of the expected Monte Carlo error. As a proof of principle, we applied to the dense SNP data of four large, extended, specific language impairment (SLI) pedigrees, and reduced the single subsample CI by 18%. In summary, confidence intervals based on should minimize re-sequencing costs beneath linkage peaks, and reduce the number of candidate genes to investigate.</p>
Necrobiosis lipoidica treated with intense pulsed light
Authors: Da Cunha Marisa Gonzaga , Rezende Flavia Cury , Da Cunha Ana Lúcia Gonzaga , Machado Filho Carlos D'Apparecida 
Published: December 2016

<p class="SectionHeading1"><span lang="EN-US">Necrobiosis Lipoidica (NL) is a chronic degenerative disease of the collagen with higher incidence on the anterior part of lower extremities, especially the tibial area. There were a number of proposed treatments, but none is 100% effective. We present a case of a fifty-year-old female patient with a suspected diagnosis of necrobiosis lipoidica, confirmed by histopathological examination. After two years of treatment with topical corticosteroids and weekly applications of Psoralen and ultraviolet A radiation (PUVA), there were no signs of improvement and we decided to perform a treatment with intense pulsed light therapy. Over a period of 14 months, a total of 13 sessions were carried out and a satisfactory treatment result was obtained.</span></p>
CULTURA E DESENVOLVIMENTO: PERSPECTIVAS HISTÓRICAS E CONTEMPORÂNEAS PARA O ESTADO DO AMAPÁ
Authors: De Lima Heluana Quintas , Moreira Fernandez Pablo Sebastian , Ferreira José Francisco De Carvalho 
Published: December 2016

O presente artigo tem como objetivo demonstrar a relação histórica e epistemológica existente entre cultura e desenvolvimento, compreendendo que a partir deste breve percurso seja possível elucidar sobre o papel da cultura conforme a compreensão de desenvolvimento colocada na contemporaneidade. Constatou-se que o crescente interesse pela dimensão cultural do desenvolvimento, ampliou esta noção e tornou-os indissociáveis, provocando variadas leituras sobre a imprescindibilidade da cultura na globalização e no Direito ao Desenvolvimento, reconhecendo a cultura como essencial à vida humana e à garantia da dignidade desta. Entretanto, este reconhecimento nas Políticas Públicas de Cultura do Amapá se demonstra recente e ainda tímido em sua institucionalização, na interação entre as esferas estatais e na constância da cultura nos planos plurianuais do referido estado
Policy Declaration and Nigerian Indigenous Languages: A Case for Improved Incentives for English Language Teachers
Authors: Ben-Iheancho Elizabeth Onyewuchi 
Published: December 2016

<p>This paper argues that the lack of commitment to implementing the declarations and language provisions of the National Policy on Education not only has adverse effects on the development of these indigenous languages, but conversely, continues to confer prime status on the place of the English language in the Nigerian education system. Further, it establishes that there is a relationship between the non implementation of policy declaration on indigenous languages and the exposure of Nigerians to the English language which in turn continues to contribute to the global status of English as the language of power and intellectual discourse. By extension therefore, onerous responsibility is placed on the teacher of the English language to properly transmit knowledge to students to equip them to meet social and educational expectations. Hence, the problem of poor performance by students at examinations all of which are written in English can be directly related to the teachers’ competence which in turn can be seen as evidence of non availability of incentives. Consequently, the paper locates the centrality of teacher welfare to increased professional competence, task delivery and productivity. Quantitative data is provided as evidence of the relationship between teacher welfare, task performance and productivity. It is discovered that the absence of these incentives has negatives implications. It concludes by recommending the need for improved English teacher specific incentives to serve as motivation for professional competence and task delivery while enhancing quality student performance and language negotiation on the global platform.</p>
The Contagious Spread of Violence Among US Adolescents Through Social Networks
Authors: Bond Robert M. , Bushman Brad J. 
Published: December 2016

Objectives. To test the hypothesis that violence among US adolescents spreads like a contagious disease through social networks. Methods. Participants were a nationally representative sample of 90 118 US students aged 12 to 18 years who were involved in the National Longitudinal Study of Adolescent Health. Violence was assessed by having participants report the number of times in the preceding 12 months they had been involved in a serious physical fight, had hurt someone badly, and had pulled a weapon on someone. Results. Participants were 48% more likely to have been involved in a serious fight, 183% more likely to have hurt someone badly, and 140% more likely to have pulled a weapon on someone if a friend had engaged in the same behavior. The influence spread up to 4 degrees of separation (i.e., friend of friend of friend of friend) for serious fights, 2 degrees for hurting someone badly, and 3 degrees for pulling a weapon on someone. Conclusions. Adolescents were more likely to engage in violent behavior if their friends did the same, and contagion of violence extended beyond immediate friends to friends of friends.
Human Trafficking of Minors and Childhood Adversity in Florida
Authors: Reid Joan A. , Baglivio Michael T. , Piquero Alex R. , Greenwald Mark A. , Epps Nathan 
Published: December 2016

Objectives. To examine the link between human trafficking of minors and childhood adversity. Methods. We compared the prevalence of adverse childhood experiences (ACEs) and cumulative childhood adversity (ACE score) among a sample of 913 juvenile justice–involved boys and girls in Florida for whom the Florida child abuse hotline accepted human trafficking abuse reports between 2009 and 2015 with those of a matched sample. Results. ACE composite scores were higher and 6 ACEs indicative of child maltreatment were more prevalent among youths who had human trafficking abuse reports. Sexual abuse was the strongest predictor of human trafficking: the odds of human trafficking was 2.52 times greater for girls who experienced sexual abuse, and there was a 8.21 times greater risk for boys who had histories of sexual abuse. Conclusions. Maltreated youths are more susceptible to exploitation in human trafficking. Sexual abuse in connection with high ACE scores may serve as a key predictor of exploitation in human trafficking for both boys and girls.
Familial Factors, Victimization, and Psychological Health Among Sexual Minority Adolescents in Sweden
Authors: Donahue Kelly , Långström Niklas , Lundström Sebastian , Lichtenstein Paul , Forsman Mats 
Published: December 2016

Objectives. To determine the influences of victimization experience and familial factors on the association between sexual minority status and psychological health outcomes among adolescents. Methods. We used data from the Child and Adolescent Twin Study in Sweden, a prospective, population-based study of all twins born in Sweden since 1992. Cross-sectional analyses included individuals who completed assessments at age 18 years (n = 4898) from 2000 to 2013. We also compared psychological health among sexual minority adolescents and their nonminority co-twins. Results. Sexual minority adolescents were more likely than were unrelated nonminority adolescents to report victimization experiences, including emotional abuse, physical abuse or neglect, and sexual abuse. Sexual minority adolescents also reported significantly more symptoms of anxiety, depression, attention-deficit/hyperactivity disorder, disordered eating, and substance misuse in addition to increased parent-reported behavior problems. Victimization experience partially mediated these associations. However, when controlling for unmeasured familial confounding factors by comparing sexual minority adolescents to their same-sex, nonminority co-twins, the effect of sexual minority status on psychological health was almost entirely attenuated. Conclusions. Familial factors—common genetic or environmental influences—may explain decreased psychological adjustment among sexual minority adolescents.
A EFETIVIDADE DA TUTELA TRABALHISTA NA REPRESSÃO AO TRABALHO ESCRAVO CONTEMPORÂNEO
Authors: Muçouçah Renato De Almeida Oliveira 
Published: December 2016

O artigo tem como escopo analisar o trabalho escravo contemporâneo e buscar formas as mais eficazes possíveis para sua repressão, verificando-se qual a tutela mais efetiva para tanto. Buscou-se, por meio da análise dedutiva de bibliografia especializada, além de sucinta apreciação indutiva de julgados, testar dedutivamente hipóteses pelas quais se pudessem dar respostas eficientes para a proteção de direitos fundamentais dos trabalhadores. A tutela trabalhista, ainda que se valha de conceito oriundo do direito penal, dialoga também com outras fontes (Convenções Internacionais ou normas penais, por exemplo): trabalho escravo não é apenas privação de liberdade, mas também da dignidade da pessoa humana. A tutela trabalhista apresenta-se mais permeável a esse conceito e permite não apenas a repressão ao trabalho escravo em sentido estrito, mas também a outras formas indignas de trabalho, sobretudo por meio de condenação por danos morais no sistema dos <em>punitive damages</em>.
Wang Chong (I a. d.) about knowledge origin and its expression in literature
Authors: Baraboshkin Konstantin Evgenievich 
Published: December 2016

The author of this article describes some of Wang Chong’s (I A.D.) thoughts about the origin of knowledge. Which in turn affects his idea about the Classics and its creators. The analysis is based on the analysis of chapters from Wang Chong’s work, which were translated by the author.
The study of perception of interface and visual design of e-government services by Moscow student youth
Authors: Vinogradova Nadezhda Sergeevna , Ponomarev Vladimir Gennadievich , Zotova Anna Sergeevna 
Published: December 2016

The results of studies related to how Moscow students perceive the interface and visual design portals «Active Citizen», «Our Moscow City », «Portal of Moscow urban services», «Medical portal EMIAS.INFO», «The official internet-portal of public services» and «Federal Bailiffs Service – Moscow» are considered in the article. These results are obtained in the course of joint research work of the Moscow Department of territorial bodies of the executive power and the K.G. Razumovsky. Moscow State University of Technologies and Management.
Phylogeny and Origin of Glucose-6-Phosphate Dehydrogenase (G6PD) Defi ciency Mutations in Indonesia
Authors: Omega Maria , Barnard Ross T. 
Published: December 2016

The aim of this study is to analyze the relationship between the types of G6PD mutations found in Indonesia and the relationships of mutations found in Indonesia to those found in other countries. We summarize the distribution of G6PDs in West Indonesia and East Indonesia. Moreover, we use bioinformatics methods to construct phylogenetic trees and compare the sequences containing the regions amplifi ed by the commonly used PCR primer pairs. Previous work has shown that Mediterranean G6PD and Chinese CoimbraG6PDare distributed in West Indonesia, whilst G6PD mutations in East Indonesia are Jammu/ViangchanG6PD and Chinese Gaohe G6PD. G6PD Jammu/Viangchan was mostly distributed in Flores Island, East Indonesia along with G6PDGaohe. We constructed phylogenetic trees using the G6PD sequences from various regions in Indonesia and other countries. It appears from phylogenetic trees and percentages of identity that FloresIndonesian G6PD defi ciency (Jammu/Viangchan G6PD, originating in India) is 92.5% identical to the G6PD defi ciency of Chinese origin (GaoheG6PD). It was interesting to note that the genetic region containing the Javanese Indonesian G6PD defi ciency (MediterraneanG6PD, fi rst found in Italy) located in the western parts of Indonesia is closely related (99% identity) to the Chinese G6PD defi ciency(Coimbra G6PD). We concludethat G6PD mutations in West Indonesia are closely related to G6PD mutations from China. G6PD mutations in East Indonesia are also closely related to G6PD mutations from India and China, but more distantly, and to different types to those in West Indonesia. A prediction of protein structure was carried out which allowed visualization of the locations of mutation on the three dimensional structure of G6PD. Key words: G6PD, phylogeny, origin, genetic mutations