bluuebunny/crossref_metadata_2025_split huggingface dataset:
Return to Sport for Skeletally Immature Athletes After ACL Reconstruction: Preventing a Second Injury Using a Quality of Movement Assessment and Quantitative Measures to Address Modifiable Risk Factors
Authors: Graziano Jessica , Chiaia Theresa , de Mille Polly , Nawabi Danyal H. , Green Daniel W. , Cordasco Frank A. 
Published: April 2017

Background: Reinjury rates after anterior cruciate ligament reconstruction (ACLR) are highest among young athletes, who consequently suffer from low rates of return to play. Historically, quantitative measures have been used to determine readiness to return to sport; however, they do not assess modifiable risk factors related to the quality of movement. Purpose: To determine the effectiveness of a criteria-based rehabilitation progression and return-to-sport criteria on efficient return to activity and prevention of second injury in young athletes post-ACLR. Study Design: Case series; Level of evidence, 4. Methods: Between December 2010 and 2013, 42 skeletally immature athletes (mean chronologic age, 12 years; range, 10-15 years) who underwent ACLR using ipsilateral hamstring tendon autograft were prospectively evaluated. All athletes progressed through a criteria-based rehabilitation progression; were assessed at specific time frames for strength, biomechanical, and neuromuscular risk factors predictive of injury; and were provided targeted interventions. The final return to sport phase consisted of quantitative testing as well as a quality of movement assessment of several functional movements with progressive difficulty and sports-specific loading. Clearance for unrestricted activity was determined by achieving satisfactory results on both qualitative and quantitative assessments with consideration for the demands of each sport. Results: The mean time for return to unrestricted competitive activity was 12 months. All but 3 (7%) athletes returned to their primary sport. Thirty-five athletes (83%) returned to unrestricted activity. Of the 6 (14%) who sustained a second injury, 3 (50%) were injured in sports they were not cleared for. All ACL reinjuries occurred in a cutting sport. Half of reinjuries occurred within 1 year of surgery, while the remaining occurred between 1 and 2 years. Eighty-three percent of reinjuries involved highly competitive cutting athletes. Conclusion: In our cohort, the combination of qualitative and quantitative data served as a good indicator for reducing risk and determining readiness to return to sport.
Surveying Batavia’s Graveyard: Geophysical controlled experiments and subsurface imaging of archaeological sites on an Indian Ocean coral island
Authors: Shragge Jeffrey , Lumley David , Issa Nader , Hoskin Tom , Paterson Alistair , Green Jeremy 
Published: April 2017

We conducted geophysical surveys on Beacon Island in the Houtman Abrolhos archipelago offshore Western Australia, to investigate areas of archaeological interest related to the 1629 Batavia shipwreck, mutiny, and massacre. We used three complementary near-surface geophysical survey techniques (total magnetic intensity, electromagnetic induction mapping, and ground-penetrating radar) to identify anomalous target zones for archaeological excavation. Interpreting near-surface geophysical anomalies is often complex and nonunique, although it can be significantly improved by achieving a better understanding of site-specific factors including background conditions, natural variability, detectability limits, and the geophysical response to, and spatial resolution of, buried targets. These factors were not well-understood for Beacon Island nor indeed for the Australian coastal environment. We have evaluated the results of controlled experiments in which we bury known targets at representative depths and analyze the geophysical responses in terms of an ability to detect and resolve targets from natural background variability. The maximum depth of detectability of calibration targets on Beacon Island is limited to approximately 0.5 m due to significant variations in background physical properties between a thin ([Formula: see text]) and highly unconsolidated dry sand, shell, and coral layer of variable thickness overlying a sea-water-saturated sandy half-space. Our controlled measurements have implications for calibrating and quantifying the interpretation of geophysical anomalies in areas of archaeological interest, particularly in coastal and sandy-coral island environments. Our geophysical analyzes contributed to the discovery of archaeological materials and five historical burials associated with the 1629 Batavia shipwreck.
Growth and reproduction of the squid Illex coindetii Verany, 1839 in the central Mediterranean Sea
Authors: CERIOLA L. , MILONE N. 
Published: April 2017

Life span, growth and cost of reproduction of Illex coindetii were examined for the first time in the southern Adriatic Sea, central Mediterranean Sea. Age and growth were investigated through statoliths reading. Cost of reproduction was explored by studying the relative investment between somatic and gonad growth. The life span of I. coindetii was less than nine months in both sexes. Females (128-234 days) showed longer life span than males (124-178 days). In both sexes the linear model best described the mantle length-at age data, while the exponential model provided the best fit to the total weight-at-age data. In terms of mantle length, females grew faster than males (average growth rate was 1.33 mm day- 1 in females and 1.00 mm day-1 in males). In terms of total weight, no significant differences were highlighted between growth curves of males and females. Mantle length, total weight, mantle weight and fin weight increased up to the latest maturity stage in both sexes. Immature and maturing individuals showed poorer body condition than mature counterparts in both sexes. Some evidences of a reproductive strategy more similar to a multiple-spawning than to a single-spawning species were found.
The elephant shark methylome reveals conservation of epigenetic regulation across jawed vertebrates
Authors: Peat Julian R. , Ortega-Recalde Oscar , Kardailsky Olga , Hore Timothy A. 
Published: April 2017

Background: Methylation of CG dinucleotides constitutes a critical system of epigenetic memory in bony vertebrates, where it modulates gene expression and suppresses transposon activity. The genomes of studied vertebrates are pervasively hypermethylated, with the exception of regulatory elements such as transcription start sites (TSSs), where the presence of methylation is associated with gene silencing. This system is not found in the sparsely methylated genomes of invertebrates, and establishing how it arose during early vertebrate evolution is impeded by a paucity of epigenetic data from basal vertebrates.Methods: We perform whole-genome bisulfite sequencing to generate the first genome-wide methylation profiles of a cartilaginous fish, the elephant sharkCallorhinchus milii. Employing these to determine the elephant shark methylome structure and its relationship with expression, we compare this with higher vertebrates and an invertebrate chordate using published methylation and transcriptome data. Results: Like higher vertebrates, the majority of elephant shark CG sites are highly methylated, and methylation is abundant across the genome rather than patterned in the mosaic configuration of invertebrates. This global hypermethylation includes transposable elements and the bodies of genes at all expression levels. Significantly, we document an inverse relationship between TSS methylation and expression in the elephant shark, supporting the presence of the repressive regulatory architecture shared by higher vertebrates.Conclusions: Our demonstration that methylation patterns in a cartilaginous fish are characteristic of higher vertebrates imply the conservation of this epigenetic modification system across jawed vertebrates separated by 465 million years of evolution. In addition, these findings position the elephant shark as a valuable model to explore the evolutionary history and function of vertebrate methylation.
New record of Steinernema arenarium (Artyukhovsky) (Rhabditida: Steinernematidae) from Ukraine and a note on its distribution
Authors: Yakovlev Yegor , Nermut Jiří , Půža Vladimír , Kharchenko Vitaliy A. , Mráček Zdeněk 
Published: April 2017

AbstractDuring a survey of the biodiversity of entomopathogenic nematodes in Ukraine, a population of
Redescription of Philometra margolisi Moravec, Vidal-Martínez et Aguirre-Macedo, 1995 (Nematoda: Philometridae), a gonad-infecting parasite of the red grouper Epinephelus morio (Serranidae) in the Gulf of Mexico
Authors: Moravec František , Bakenhaster Micah D. , Leone Erin H. 
Published: April 2017

AbstractThe insufficiently known nematode species
Toxoplasma gondii in backyard pigs: seroepidemiology and mouse bioassay
Authors: Samico-Fernandes Erika Fernanda Torres , Samico-Fernandes Marcela Fernanda Torres , de Albuquerque Pedro Paulo Feitosa , de Almeida Jonatas Campos , de Souza Santos André , da Rocha Mota André , de Souza Neto Orestes Luiz , Mota Rinaldo Aparecido 
Published: April 2017

AbstractThe aim of this study was to evaluate the occurrence of
The Apollo Group Asteroid 2008 OS9: Discovery, Orbit, Rotation and the Yarkovsky/YORP Effects
Authors: Černis K. , Eglitis I. , Wlodarczyk I. , Zdanavičius J. , Zdanavičius K. 
Published: April 2017

Abstract
A project for astrometric and photometric observations of asteroids at the Baldone Observatory is described. One of the most important results of the project is the discovery of 2008 OS9, a 600 meter asteroid of the NEO Apollo group. The results of its astrometric and photometric observations at the Molėtai and Baldone observatories are presented. From the brightness variation with the 0.27 mag amplitude, a rotation period of 8.430 ± 0.005 h is determined. Close approaches of the asteroid to Earth and Venus during the next millenium are predicted. The mean values of secular changes in the semi-major axis, eccentricity and inclination are computed with and without the Yarkovsky and YORP effects. A negative value of the difference between the value of semi-major axis computed with the Yarkovsky and YORP effects and without them, da/dt, may indicate retrograde rotation of the asteroid.
Vascular calcification: the role of microRNAs
Authors: Alkagiet Stelina , Tziomalos Konstantinos 
Published: April 2017

AbstractVascular calcification represents the deposition of calcium phosphate salts in the tunica media of the vascular wall. It occurs during aging but is accelerated and pronounced in patients with diabetes mellitus, chronic kidney disease (CKD) and established cardiovascular disease. Due to the loss of elasticity of the vessel wall, vascular calcification might result in left ventricular hypertrophy and compromise coronary perfusion. Accordingly, several studies showed that vascular calcification is associated with increased risk for cardiovascular morbidity and mortality. Accumulating data suggest that microRNAs (miRs) play an important role in vascular calcification. A variety of miRs have been implicated in the development of vascular calcification, whereas others appear to play a protective role. Accordingly, miRs might represent promising targets for the prevention of vascular calcification and its adverse cardiovascular sequelae. However, given the complexity of regulation of this process and the multitude of miRs involved, more research is needed to identify the optimal candidate miRs for targeting.
Nodal length of Steklov eigenfunctions on real-analytic Riemannian surfaces
Authors: Polterovich Iosif , Sher David A. , Toth John A. 
Published: April 2017

Abstract
We prove sharp upper and lower bounds for the nodal length of Steklov eigenfunctions on real-analytic Riemannian surfaces with boundary. The argument involves frequency function methods for harmonic functions in the interior of the surface as well as the construction of exponentially accurate approximations for the Steklov eigenfunctions near the boundary.
Time, Space, Dummett and McTaggart
Authors: Garrett Brian 
Published: April 2017

Abstract
Michael Dummett’s fecund and uncharacteristically brief article “A Defence of McTaggart’s Proof of the Unreality of Time” offers a well-known interpretation of McTaggart’s proof, and makes a number of controversial claims about a range of inter-connected theses concerning time and space. I want to sort out what is plausible in what Dummett says from what is not, and identify which theses should be endorsed by A theorists and which by B theorists. It is important, even today, to get clear about these issues and their bearing on Dummett’s interpretation of McTaggart.
Subjectivity and generativity in midlife
Authors: Wojciechowska Ludwika 
Published: April 2017

Abstract
An important aspect of human development in midlife is, according to E. Erikson’s theory, the successful resolution of the crisis between generativity and stagnation. Generativity is understood as focusing one’s energy on productivity and creativity - the creation of new works and ideas dedicated to future generations. It is assumed that generativity results from personal needs and constitutes a response to the social expectations directed at individuals. Concern for the next generation does not go hand-in-hand with concern for the personal development of a person in midlife and this imbalance may lead to a psychological discomfort and a sense of martyrdom. Accordingly, it can therefore be concluded that a person focusing on the well-being of the social environment and neglecting her/himself is incapable of feeling that they are a subject that manages their fate and makes decisions enabling them to achieve personal psychological well-being. It could, therefore, be expected that the fulfilment of generative goals may lead to a reduction in the psychological well-being of a representative of middle adulthood. Empirical data has not confirmed this expectation.
Masculinity Ideology and Subjective Well-Being in a Sample of Polish Men and Women
Authors: Pietraszkiewicz Agnieszka , Kaufmann Michèle C. , Formanowicz Magdalena M. 
Published: April 2017

Abstract
Masculinity ideology is defined as a blend of cultural beliefs, types of behavior, and roles generally associated with men and boys. Previous studies have showed mixed effects of adherence to masculine ideology on men’s subjective well-being, indicating negative but also positive relationships. The present study focuses on agency, that is the core of stereotypic masculinity (Abele & Wojciszke, 2007), and its relationship to subjective well-being by analyzing data from a representative Polish sample of the European Social Survey (ESS). Participants were 1751 adults, aged 17 years and older (of whom 771 were men). A structural equation model was applied. The results demonstrated that agentic values (specifically valuing power and achievement) were good predictors of male and female subjective well-being. That is, the less men and women valued their own power and achievements, the lower their subjective well-being was. As expected, this association was stronger for men. Additionally, regardless of gender, we demonstrated that age was a negative predictor and that number of years of education a positive predictor of subjective well-being. This association was stronger for men.
Circonscript Subcutaneous Arteriovenous Malformation of the Head
Authors: Mirchevski Vladimir , Zogovska Elizabeta , Chaparoski Aleksandar , Filipce Venko , Kostov Milenko , Mirchevski Mirko Mishel 
Published: April 2017

Abstract
The aim of this study is to show the various possibilities to treat this rare malformation, accentuating the results of the early surgical treatment before complications.
Material: The authors present 8 cases of patients with subcutaneous arteriovenous malformations, 5 females and 3 males (age of 7, 13, 19, 23, 27, 52 and 58 years) treated in the period of 1999 until 2015 at the Clinic for Neurosurgery and the Clinic for Plastic, Aesthetic and Reconstructive Surgery in Skopje, Republic of Macedonia. This malformation has been observed by the parents in the childhood, around the age of 3 years in all cases. Local red circonscripted nodule, soft, with manually discharging tendency and varicose dilated veins have been observed in all cases, deaf on both sides in one case, while in the older case, a cavernous sinus thrombosis caused unilateral exophthalmia, hyaline indurated ophthalmic vein, vertigo, arrhythmia, heart failure and bradypsychia have been observed. The size of the malformation has been from 2.5 to 7 cm. The diagnostics was done using CT, CT-angiography and digital angiography including external carotid angiography. Endocranial arterials peduncle was present in all cases.
Results: Six cases underwent surgery, while two cases were treated with several treatments of endovascular embolization. The follow up has been ranged from 2 to 15 years. All surgically treated patients improved without recurrence, the exophthalmia, bradypsychia and the heart problems regressed, while in patients treated with endovascular non-complete occlusion the AVM decreased, but still remained.
In conclusion: The Surgical treatment remains a first option if it is possible, and as earlier as possible, while embolization is a useful tool in cases where a complete excision is not possible.
Les structures sémantiques profondes du code pénal chinois
Authors: Lin Zhu 
Published: April 2017

RésuméGreimas applique aux structures narratives profondes du récit le carré sémiotique servant à représenter l’émergence de la signification à l’intérieur d’une structure. Dans le présent article, nous essayons d’extraire les structures sémantiques profondes du code pénal chinois en adaptant le carré greimassien aux spécificités du discours juridique. Du modèle sémiotique constitutionnel du code pénal à ses deux substructures, en passant par l’analyse de l’épistémé qui commande leur manifestation, nos analyses essaient de faire ressortir les spécificités typiques du discours juridique qui nous paraissent incontournables pour l’analyse sémiotique de ce type de discours particulier
Frühe Bilder in der Ontogenese
Authors: Maurer Dieter 
Published: April 2017

Zusammenfassung
Der vorliegende Aufsatz unternimmt den Versuch, die Morphologie früher Bilder in der Ontogenese auf der Grundlage ausgedehnter phänomenologischer und dokumentarischer Studien zusammenfassend darzustellen, im Sinne einer Revision bisheriger Darstellungen in der Literatur, welche frühe Bilder häufig unter den Bezeichnungen „Kritzeleien“ und „frühe Kinderzeichnung“ abhandeln. Mit dieser Zusammenfassung soll gleichzeitig die „Logik“, der bildhafte Begründungszusammenhang von frühen graphischen Merkmalen, Strukturbildungen und Entwicklungstendenzen deutlich werden. Die Darstellungen sind dabei in erster Linie darauf ausgerichtet, verschiedenen Bereichen der Wissenschaft wie der Praxis eine Einleitung für ein nachfolgendes vertiefendes Studium sowie für weiterführende Einschätzungen und Interpretationen früher Bilder anzubieten. In diesem Sinne sind die Darstellungen verbunden mit ausgedehnten illustrierenden Bild- und Videodokumenten, welche online frei zugänglich sind.
Comparison of the Hang High Pull and Loaded Jump Squat for the Development of Vertical Jump and Isometric Force-Time Characteristics
Authors: Oranchuk Dustin J. , Robinson Tracey L. , Switaj Zachary J. , Drinkwater Eric J. 
Published: April 2017

Abstract
Oranchuk, DJ, Robinson, TL, Switaj, ZJ, and Drinkwater, EJ. Comparison of the hang high pull and loaded jump squat for the development of vertical jump and isometric force-time characteristics. J Strength Cond Res 33(1): 17–24, 2019—Weightlifting movements have high skill demands and require expert coaching. Loaded jumps have a comparably lower skill demand but may be similarly effective for improving explosive performance. The purpose of this study was to compare vertical jump performance, isometric force, and rate of force development (RFD) after a 10-week intervention using the hang high pull (hang-pull) or trap-bar jump squat (jump-squat). Eighteen National Collegiate Athletic Association Division II swimmers (8 males, 10 females) with at least 1 year of resistance training experience volunteered to participate. Testing included the squat jump (SJ), countermovement jump, and the isometric midthigh pull (IMTP). Vertical ground reaction forces were analyzed to obtain jump height and relative peak power. Relative peak force, peak RFD, and relative force at 5 time bands were obtained from the IMTP. Subjects were randomly assigned to either a hang pull (n = 9) or jump-squat (n = 9) training group and completed a 10-week, volume-equated, periodized training program. Although there was a significant main effect of training for both groups, no statistically significant between-group differences were found (p ≥ 0.17) for any of the dependent variables. However, medium effect sizes in favor of the jump-squat training group were seen in SJ height (d = 0.56) and SJ peak power (d = 0.69). Loaded jumps seem equally effective as weightlifting derivatives for improving lower-body power in experienced athletes. Because loaded jumps require less skill and less coaching expertise than weightlifting, loaded jumps should be considered where coaching complex movements is difficult.
Downregulation of RBO-PI4KIIIα Facilitates Aβ42Secretion and Ameliorates Neural Deficits in Aβ42-ExpressingDrosophila
Authors: Zhang Xiao , Wang Wen-An , Jiang Li-Xiang , Liu Hai-Yan , Zhang Bao-Zhu , Lim Nastasia , Li Qing-Yi , Huang Fu-De 
Published: April 2017

Phosphoinositides and their metabolizing enzymes are involved in Aβ42metabolism and Alzheimer's disease pathogenesis. In yeast and mammals, Eighty-five requiring 3 (EFR3), whoseDrosophilahomolog is Rolling Blackout (RBO), forms a plasma membrane-localized protein complex with phosphatidylinositol-4-kinase Type IIIα (PI4KIIIα) and a scaffold protein to tightly control the level of plasmalemmal phosphatidylinositol-4-phosphate (PI4P). Here, we report that RBO binds toDrosophilaPI4KIIIα, and that in an Aβ42-expressingDrosophilamodel, separate genetic reduction of PI4KIIIα and RBO, or pharmacological inhibition of PI4KIIIα ameliorated synaptic transmission deficit, climbing ability decline, premature death, and reduced neuronal accumulation of Aβ42. Moreover, we found that RBO-PI4KIIIa downregulation increased neuronal Aβ42release and that PI4P facilitated the assembly or oligomerization of Aβ42in/on liposomes. These results indicate that RBO-PI4KIIIa downregulation facilitates neuronal Aβ42release and consequently reduces neuronal Aβ42accumulation likely via decreasing Aβ42assembly in/on plasma membrane. This study suggests the RBO-PI4KIIIα complex as a potential therapeutic target and PI4KIIIα inhibitors as drug candidates for Alzheimer's disease treatment.SIGNIFICANCE STATEMENTPhosphoinositides and their metabolizing enzymes are involved in Aβ42metabolism and Alzheimer's disease pathogenesis. Here, in an Aβ42-expressingDrosophilamodel, we discovered and studied the beneficial role of downregulating RBO or its interacting protein PI4KIIIα—a protein that tightly controls the plasmalemmal level of PI4P—against the defects caused by Aβ42expression. Mechanistically, RBO-PI4KIIIα downregulation reduced neuronal Aβ42accumulation, and interestingly increased neuronal Aβ42release. This study suggests the RBO-PI4KIIIα complex as a novel therapeutic target, and PI4KIIIα inhibitors as new drug candidates.