bluuebunny/crossref_metadata_2025_split huggingface dataset:
Den rummelige forskningsdiagnose: Om fravær og forhandlingsrum i tilblivelsen af en diagnose
Authors: Brix Tina Kaia Stokvad , Wind Gitte 
Published: July 2017

Antropologiske studier af diagnoser har fra mange forskellige vinkler diskuteret og belyst, hvilken social betydning det kan have at være diagnosticeret med en bestemt diagnose – og, tilsvarende, hvad det kan betyde at mangle en diagnose. Bodily Distress Syndrome (BDS) er en ny forskningsdiagnose, der endnu ikke figurerer i de internationale diagnosemanualer, og som i en vis forstand befinder sig i krydsfeltet mellem diagnose og ’ikke-diagnose’.På baggrund af et etnografisk feltarbejde i Danmark udforsker vi i artiklen, hvilke forhandlingsmuligheder der for mennesker med Bodily Distress Syndrome knytter sig til at blive diagnosticeret med en forskningsdiagnose. Med fokus på diagnosens tilblivelsesfase viser vi, at den særlige ikke-synlighed, der ligger indlejret i BDS-diagnosen, i visse sammenhænge er forbundet med bestemte muligheder for mennesker med BDS. Ud fra en teoretisk forståelse af fravær som ejendel, argumenterer vi for, at ikke-synligheden åbner op for et rum for forhandling om diagnosens indholdsmæssige beskaffenhed, og at mennesker med BDS – i dette forhandlingsrum – kan tage medejerskab over tilblivelsen og afgrænsningen af BDS som diagnose og fænomen.A room for negotiation – On absence and flexibility in the becoming of a diagnosisAnthropological studies of diagnoses have from several perspectives discussed and shed light on the social meaning and implication of having or not having a diagnosis. Bodily Distress Syndrome (BDS) is a new research diagnosis that does not yet appear in WHO’s International Classification of Diseases. In that sense BDS is situated in a position of structural ambiguity, simultaneously being and not being a real diagnosis.Based on ethnographic fieldwork in Denmark this article examines the possibilities of negotiation connected to being diagnosed with a research diagnosis. Focusing on the very becoming of BDS the article suggests that the absence in the diagnosis of clear pathological findings offers certain possibilities to people recently diagnosed with BDS. Leaning on a theoretical understanding of absence as a specific kind of possession, we argue that the absence opens up a room for negotiation of the content of the diagnosis, thereby offering people with BDS a shared ownership of the becoming and elaboration of the phenomenon BDS.
The Wisdom of the Crowd Can Unmask Faces
Authors: Carragher Daniel J. , Hancock Peter J. B. 
Published: October 2024

ABSTRACTAccurately determining whether two images show the same person is a surprisingly difficult task, which becomes even harder if one or both faces are wearing medical face masks. Attempts to improve unfamiliar face matching accuracy have generally had limited success. Although one brief training program improved masked face matching accuracy by 4.9%, this increase would not overcome the entire performance deficit caused by masks. Here, we investigate whether combining independent identification decisions from different individuals can improve masked face matching performance through the wisdom of the crowd effect. Accuracy gains emerged reliably after combining the decisions of three individuals, culminating in significant improvements of 11%–26% among the largest crowds. Despite creating crowds of up to 80 people, half of the eventual improvement had generally already occurred in crowds of 6 individuals. The wisdom of the crowd effect is a highly effective approach to improving accuracy when identifying masked faces.
Experimental Detection of Topological Electronic State and Large Linear Magnetoresistance in SrSn4 Superconductor
Authors: Pariari Arnab Kumar , Sharma Rajesh O , Balal Mohammad , Hücker Markus , Das Tanmoy , Barman Sudipta Roy 
Published: October 2024

AbstractWhile recent experiments confirm the existence of hundreds of topological electronic materials, only a few exhibit the coexistence of superconductivity (SC) and a topological electronic state. These compounds attract significant attention in forefront research because of the potential for the existence of topological SC, paving the way for future technological advancements. SrSn4 is known for exhibiting unusual SC below the transition temperature (TC) of 4.8 K. Recent theory predicts a topological electronic state in this compound, which is yet to be confirmed by experiments. Systematic and detailed studies of the magnetotransport properties of SrSn4 and its Fermi surface characterizations are also absent. For the first time, a quantum oscillation study reveals a nontrivial 𝝅‐Berry phase, very light effective mass, and high quantum mobility of charge carriers in SrSn4. Magnetotransport experiment unveils large linear transverse magnetoresistance (TMR) of more than 1200% at 5 K and 14 T. Angle‐dependent transport experiments detect anisotropic and fourfold symmetric TMR, with the maximum value (≈2000%) occurring when the angle between the magnetic field and the crystallographic b‐axis is 45°. The results suggest that SrSn4 is the first topological material with SC above the boiling point of helium that displays such high magnetoresistance.
Interface Engineering with an Organic Aluminum Additive for High‐Rate Sodium Metal Batteries
Authors: Wang Xihao , Wu Yehui , Zhou Yuhan , Zheng Weiran , Zhang Kun , Ma Xingyu , Bai Tiansheng , Li Deping , Ci Lijie , Grey Clare P. , Lu Jingyu 
Published: October 2024

AbstractInterface stability is a key to practical applications of high‐rate sodium metal batteries (SMBs). The general sodium metal anode (SMA), for example, suffers from an unstable solid electrolyte interface (SEI), which may induce severe dendrite growth and continuous Na consumption, particularly under high rates. At the same time, the cathode electrolyte interface (CEI) of a widely adopted cathode material Na3V2(PO4)3 (NVP) has to tolerate the massive volume changes during the rapid Na+ ion intercalation/extraction, resulting in structural degradations and the capacity loss. Here, a facile strategy is reported by introducing aluminum ethoxide to a conventional ether‐based electrolyte, to promote the formation of an alumina‐rich SEI and CEI, which facilitates the rapid Na+ ion transport across the interface and promotes the uniform Na deposition. The resultant Na || Na symmetric cell demonstrates a stable cycling of 4800 h at 10 mA cm−2 and 1 mAh cm−2, and a Na || NVP full cell exhibits a high capacity retention of 81.28% after 6000 cycles at 40C. The simultaneous interface engineering of both the Na metal anode and the NVP cathode via the facile organic aluminum additive opens up a new avenue toward practical application of high‐rate SMBs.
3D Printed Ordered Hierarchically‐Porous Electrodes for Developing High‐Performance Quasi‐Solid‐State Aqueous Nickel‐Iron Batteries
Authors: Kong Dezhi , Li Weidong , Chu Ningning , Guo Zhengyang , Wang Tenghui , Wang Hui , Xu Tingting , Zang Jinhao , Li Xinjian , Luo Yongsong , Wang Ye , Yang Hui Ying 
Published: October 2024

AbstractStructural engineering offers a viable and broadly applicable approach for further enhancing the energy density of aqueous nickel‐iron (Ni‐Fe) batteries without changing the fundamental battery chemistries. Herein, the synthesis of 3D printed low‐tortuosity and ultra‐thick ordered hierarchically porous reduced graphene oxide (rGO)‐based microlattice electrodes for high‐performance aqueous Ni‐Fe batteries through direct writing (DIW) 3D printing technology is presented. Significantly, the areal specific capacitance of the 3D printed electrodes scales positively with electrode thickness, whereas the gravimetric capacitance remains relatively constant, indicating that the capacitive performance is not constrained by ion diffusion and exhibits rapid kinetic behavior, even at elevated mass‐loading levels and in the context of ultra‐thick electrodes. Based on a 3 m KOH aqueous electrolyte, the 3D printed aqueous Ni‐Fe cell (thickness: ≈2 mm) exhibits high areal specific capacity (≈0.353 mAh cm−2), high volumetric energy/power density (≈1.15 mWh cm−2 at 48.00 mW cm−2), and excellent long‐term cycling performance (≈81.25% capacitance retained after 5000 cycles). As a micro‐battery device, 3D printed quasi‐solid‐state Ni‐Fe battery (3DP QSS Ni‐Fe) device with 4 mm thickness still exhibits a high areal capacity of 0.525 mAh cm−2, and excellent cycle stability with ≈81.1% capacity retention after 10000 cycles. The promising 3D printed strategy provides a novel avenue for the controllable assembly of higher‐dimensional architectures, thereby paving the way for the advancement of next‐generation materials and devices.
A Highly Optical Anisotropic Hybrid Metal Halide for Modulation and Generation of Polarized Light
Authors: Xu Qianting , Wang Ziyi , Zhou Yang , Huang Weiqi , Song Yipeng , Zheng Jieyu , Li Yanqiang , Hou Linxi , Luo Junhua , Zhao Sangen 
Published: October 2024

AbstractPolarized light is critical for a wide range of applications in modern optics. However, its generation and modulation typically require additional optical comments, which hinders device compactness. Herein, an air‐stable Tin(IV)‐based hybrid metal halide, (C10H9N2O)2SnCl6, composed of [C10H9N2O]+ cations and isolated [SnCl6]2− octahedra is reported. Notably, (C10H9N2O)2SnCl6 exhibits a robust birefringence of 0.50@550 nm that is evidently larger than those of commercially used crystals, which enables efficient modulation of polarized light. Moreover, it possesses a broad polarized blue emission in the range of 374–600 nm with a peak at 426 nm. Theoretical and structural studies reveal that the high optical anisotropy for large birefringence and directly polarized emission of (C10H9N2O)2SnCl6 is ascribed to the cooperative effect of distortion of [SnCl6]2− and high π‐conjugation of [C10H9N2O]+ in parallel arrangement. This work may provide new thoughts on designing and realizing the miniaturization of polarization‐resolved optoelectronic devices.
From Spheroids to Bioprinting: A Literature Review on Biomanufacturing Strategies of 3D In Vitro Osteosarcoma Models
Authors: Domingues Margarida F. , Silva João C. , Sanjuan‐Alberte Paola 
Published: October 2024

AbstractOsteosarcoma (OS) is a rare primary malignant bone cancer affecting mainly young individuals. Treatment typically consists of chemotherapy and surgical tumor resection, which has undergone few improvements since the 1970s. This therapeutic approach encounters several limitations attributed to the tumor's inherent chemoresistance, marked heterogeneity and metastatic potential. Therefore, the development of in vitro platforms that closely mimic the OS pathophysiology is crucial to understand tumor progression and discover effective anticancer therapeutics. Contrary to 2D monolayer cultures and animal models, 3D in vitro platforms show promise in replicating the 3D tumor macrostructure, cell‐cell and cell‐extracellular matrix interactions. This review provides an overview of the biomanufacturing strategies employed in developing 3D in vitro OS models, highlighting their role in replicating different aspects of OS and improving OS anticancer research and drug screening. A variety of 3D in vitro models are explored, including both scaffold‐free and scaffold‐based models, encompassing cell spheroids, hydrogels, and innovative approaches like electrospun nanofibers, microfluidic devices and bioprinted constructs. By examining the distinctive features of each model type, this review offers insights into their potential transformative impact on the landscape of OS research and therapeutic innovation, addressing the challenges and future directions of 3D in vitro OS modeling.
Deubiquitylase USP52 Promotes Bladder Cancer Progression by Modulating Ferroptosis through Stabilizing SLC7A11/xCT
Authors: Liu Jianmin , Luo Yongwen , Chen Siming , Wang Gang , Jin Wan , Jiang Wenyu , Li Mingxing , Wang Yejinpeng , Yu Jingtian , Wei Houyi , Zhang Renjie , Zhou Fenfang , Ju Lingao , Zhang Yi , Xiao Yu , Qian Kaiyu , Wang Xinghuan 
Published: October 2024

AbstractBladder cancer (BLCA) is a prevalent cancer with high case‐fatality rates and a substantial economic burden worldwide. Understanding its molecular underpinnings to guide clinical management is crucial. Ferroptosis, a recently described non‐apoptotic form of cell death, is initiated by the lethal accumulation of iron‐dependent lipid peroxidation products. Despite growing interest, the roles and vulnerabilities determining ferroptosis sensitivity in BLCA remain unclear. Re‐analysis of single‐cell RNA data reveals a decrease in high‐ferroptosis cancer cells as BLCA advances. USP52/PAN2 is identified as a key regulator of ferroptosis in BLCA through an unbiased siRNA screen targeting 96 deubiquitylases (DUBs). Functionally, USP52 depletion impedes glutathione (GSH) synthesis by promoting xCT protein degradation, increasing lipid peroxidation and ferroptosis susceptibility, thus suppressing BLCA progression. Mechanistically, USP52 interacts with xCT and enzymatically cleaves the K48‐conjugated ubiquitin chains at K4 and K12, enhancing its protein stability. Clinical BLCA samples demonstrate a positive correlation between USP52 and xCT expression, with high USP52 levels associated with aggressive disease progression and poor prognosis. In vivo, USP52 depletion combined with ferroptosis triggers imidazole ketone Erastin (IKE) synergistically restrains BLCA progression by inducing ferroptosis. These findings elucidate the role of the USP52‐xCT axis in BLCA and highlight the therapeutic potential of targeting USP52 and ferroptosis inducers in BLCA.
Ferric Iron/Shikonin Nanoparticle‐Embedded Hydrogels with Robust Adhesion and Healing Functions for Treating Oral Ulcers in Diabetes
Authors: Chen Xiaojing , Li Zhangping , Ge XinXin , Qi Xiaoliang , Xiang Yajing , Shi Yizuo , Li Ying , Pan Yao , Wang Yingying , Ru Yiyu , Huang Kelei , Shao Jiatan , Shen Jianliang , Li He 
Published: October 2024

AbstractOral ulcers can be addressed using various biomaterials designed to deliver medications or cytokines. Nevertheless, the effectiveness of these substances is frequently limited in many patients due to poor adherence, short retention time in the mouth, and less‐than‐optimal drug efficacy. In this study, a new hydrogel patch (FSH3) made of a silk fibroin/hyaluronic acid matrix with light‐sensitive adhesive qualities infused with ferric iron/shikonin nanoparticles to enhance healing effects is presented. Initially, this hydrogel forms an adhesive barrier over mucosal lesions through a straightforward local injection, solidifying when exposed to UV light. Subsequently, FSH3 demonstrates superior reactive oxygen species elimination and near‐infrared photothermal bactericidal activity. These characteristics support bacterial elimination and regulate oxidative levels, promoting a wound's progression from inflammation to tissue regeneration. In a diabetic rat model mimicking oral ulcers, FSH3 significantly speeds up healing by adjusting the inflammatory environment of the injured tissue, maintaining balance in oral microbiota, and promoting faster re‐epithelialization. Overall, the light‐sensitive FSH3 hydrogel shows potential for rapid wound recovery and may transform therapeutic methods for managing oral ulcers in diabetes.
Black Phosphorus Nanosheets‐Loaded Mussel‐Inspired Hydrogel with Wet Adhesion, Photothermal Antimicrobial, and In Situ Remineralization Capabilities for Caries Prevention
Authors: Ran Ying , Shi Jiayi , Ding Yiqin , Li Lujian , Lu Dandan , Zeng Youyun , Qiu Dongchao , Yu Jie , Cai Xiaojun , Pan Yihuai 
Published: October 2024

AbstractThe main features of early caries are the massive colonization of cariogenic bacteria and demineralization of tooth enamel by the acids that they produce. Owing to the lack of effective treatments, the development of anticaries therapeutics with both antimicrobial and remineralizing properties is urgently required. Black phosphorus nanosheets (BPNs) are ideal therapeutics for the treatment of early caries because they can mediate photothermal antibacterial activity and subsequently promote remineralization by generating PO43−. However, the dynamic and wet environment of the oral cavity prevents the long‐term adhesion of BPNs to the tooth surface. In this study, using catechol‐modified chitosan and PLGA‐PEG‐PLGA as raw materials, a mussel‐inspired versatile hydrogel, BP@CP5, is presented that can be used to physically load BPNs. BP@CP5 has exceptional injectability and can firmly adhere to tooth surfaces for up to 24 h. Upon irradiation, BP@CP5 can quickly eliminate ≈99% of Streptococcus mutans and Streptococcus sanguinis; furthermore, the PO43− generated via degradation also promotes rapid remineralization of enamel slabs. Importantly, the vivo rodent caries modeling results further confirm the excellent caries‐prevention properties of BP@CP5. This study demonstrates that BP@CP5 is a promising anticaries material for caries management.
Investigating the Effect of Incorporating Dimethylaminopropyl Side Chains into a Naphthalenediimide‐Based Conjugated Polymer
Authors: Liu Tzu‐Lun , Lai Yu‐Ying 
Published: October 2024

AbstractTwo approaches—fractional side‐chain truncation and complementary interactions—are employed in this study. In fractional side‐chain truncation, NDIDmap with the naphthalene diimide (NDI) group and the 3‐(dimethylamino)propyl (Dmap) chain is incorporated into P(NDI2OD‐T2), yielding various copolymers. Increasing the amount of NDIDmap in the polymer enhances π‐isotropy, which can improve charge transport. In complementary interactions, the NDIDmap group complexes with tris(pentafluorophenyl)borane (BCF) via complementary N–B interactions. Adding BCF to a naphthalenediimide‐based conjugated polymer with NDIDmap enhances the coherence length (Lc) of π‐stacking. However, the elongated Lc does not result in superior electron mobility, challenging the conventional perspective that long‐range π‐order is crucial for charge transport. For comparison, triphenylamine (TPA), which is electronically distinct from BCF, is used. TPA affects the thin‐film microstructure and charge‐transport parameters differently from BCF. Although the improvement in electron mobility is not very significant, this study demonstrates the effects of fractional side‐chain truncation and complementary interactions on the thin‐film microstructure and charge transport of naphthalenediimide‐based conjugated polymers, paving the way for further side‐chain engineering.
Metal‐Semiconductor Phase Transition in Multilayer VSe2 for Broadband Photodetector with High Sensitivity
Authors: Yang Yujue , Xia Mengjia , Zhao Qixiao , Pan Zhidong , Dong Huafeng , Zhang Xin , Wu Fugen , Yang Juehan , Huo Nengjie 
Published: October 2024

Abstract2D 1T‐VSe2 is a charge‐density wave (CDW) system that also exhibits room‐temperature ferromagnetism, making it promising for photodetecting devices. However, the sensitivity of 1T‐VSe2 photodetectors is limited by the high dark current due to its metallic feature of T‐phase VSe2. So far, photodetectors based on semiconducting 2H‐phase VSe2 have ever been reported. In this work, the metal‐semiconductor phase transition (1T to 2H) in multilayer VSe2 by thermal annealing process, and the fabrication of 2H‐VSe2 broadband photodetectors with high sensitivity is reported. The 2H‐VSe2 photodetectors exhibit low dark current and a broad spectral range of 405–1550 nm. The responsivity (R) and detectivity (D*) can reach up to 75.26 A W−1 and 1.45 × 1010 Jones at Vsd of 1 V, outperforming photodetectors based on 1T‐VSe2 and other 2D materials for the 1550 nm optical communication band. This work showcases a facile method for obtaining the metal‐semiconductor phase transition of VSe2 and demonstrates the potential of 2H‐VSe2 for high‐performance near‐infrared photodetectors.
Association of handgrip strength weakness and asymmetry with later life pain risk in middle‐aged and older individuals: Results from four prospective cohorts
Authors: Zhu Yuanpeng , Zhang Haoran , Zhang Terry Jianguo , Wu Nan 
Published: October 2024

AbstractObjectivesThe burden of pain in middle‐aged and older adults is considerable and significantly increases healthcare expenditures. We aimed to investigate the roles of handgrip strength (HGS) weakness and asymmetry in predicting pain across four nationally representative cohorts.MethodsThis longitudinal study utilized data from four major surveys: the Health and Retirement Study (HRS); the English Longitudinal Study of Ageing (ELSA); the Survey of Health, Ageing and Retirement in Europe (SHARE); and the China Health and Retirement Longitudinal Study (CHARLS). Multivariable cubic regression splines were employed to visually explore the nonlinear associations between HGS and pain in each cohort. The Cox proportional hazard model was applied to analyze the independent and combined relationship between HGS weakness and asymmetry and pain risk.ResultsWe included 41,171 participants in the final analysis, with a mean follow‐up period of 4.68 ± 2.61 years (50.7% female, mean age 64.3 ± 9.3 years). No nonlinear relationship was found between HGS and pain incidence (nonlinear p < 0.05 in ELSA and SHARE; >0.05 in CHARLS and HRS). After adjustment, the highest quartile groups had a significantly reduced risk of pain compared to the lowest quartile groups across all cohorts, with hazard ratios of 0.81 (0.74, 0.89) in CHARLS, 0.86 (0.77, 0.97) in HRS, 0.88 (0.77, 0.98) in ELSA, and 0.78 (0.73, 0.84) in SHARE. Participants with normal HGS had approximately 20% lower risk of pain compared to those with weak HGS. Each 5 kg increase in HGS was associated with decreased hazard ratios for pain: 0.95 (0.93, 0.97) in CHARLS, 0.97 (0.94, 0.99) in HRS, 0.96 (0.94, 0.99) in ELSA, and 0.94 (0.92, 0.95) in SHARE. The association between HGS asymmetry and pain risk was significant only in a few cohorts (HRS at 10%, 1.10 (1.03, 1.18); SHARE at 30%, 1.12 (1.05, 1.21)). No interaction effect between HGS weakness and asymmetry on pain risk was observed (all p‐values for interaction >0.05).ConclusionsOur findings suggest that HGS can be used as an independent predictor of pain in middle‐aged and older European, American, and Chinese populations. However, our results do not support the use of HGS asymmetry as an independent predictor of pain risk. It is necessary to establish appropriate criteria for HGS asymmetry across different populations. The use of both weak HGS and asymmetry as predictors of health outcomes requires further validation in more diverse populations.