bluuebunny/crossref_metadata_2025_split huggingface dataset:
New mothers’ feelings of disappointment and failure after cesarean delivery
Authors: Kjerulff Kristen H. , Brubaker Laura H. 
Published: October 2017

AbstractBackgroundChildbirth is an important life event and how women feel in retrospect about their first childbirth may have long‐term effects on the mother, child, and family. In this study, we investigated the association between mode of delivery at first childbirth and birth experience, using a new scale developed specifically to measure women's affective response.MethodsThis was a prospective cohort study of 3006 women who were interviewed during pregnancy and 1‐month postpartum. The First Baby Study Birth Experience Scale was used to measure the association between mode of delivery and women's postpartum feelings about their childbirth, taking into account relevant confounders, including maternal age, race, education, pregnancy intendedness, depression, social support, and maternal and newborn complications by way of linear and logistic regression models.ResultsWomen who had unplanned cesarean delivery had the least positive feelings overall about their first childbirth, in comparison to those whose deliveries were spontaneous vaginal (P < .001), instrumental vaginal (P = .001), and planned cesarean (P < .001). In addition, those who delivered by unplanned cesarean were more likely to feel disappointed (adjusted odds ratio [OR] 6.21 [95% confidence interval (CI) 4.62‐8.35]) and like a failure (adjusted OR 5.09 [95% CI 3.65‐7.09]) in comparison to women who had spontaneous vaginal delivery; and less likely to feel extremely or quite a bit proud of themselves (adjusted OR 2.70 [95% CI 2.20‐3.30]).ConclusionsDelivering by unplanned cesarean delivery adversely affects how women feel about their first childbirth in retrospect, and their self‐esteem.
Utility of reproductive life plans in identification of potentially teratogenic medication use: A pilot study
Authors: DiPietro Mager Natalie , Mills Caitlin , Snelling April 
Published: October 2017

AbstractBackgroundTeratogenic medications increase risks of miscarriage, fetal death, and/or birth defects. It is important to identify whether women of childbearing potential are taking these medications and to minimize exposure to these agents through change in drug therapy before conception and/or use of effective contraception to prevent conception.ObjectiveTo determine the utility of reproductive life plans as tools to identify women using potentially teratogenic medications.MethodsA retrospective review was conducted on reproductive life plans completed by women receiving services as part of the Toledo‐Lucas County Healthy Start program. The medication section of the reproductive life plan was reviewed to determine: if it was completed; categories of medications reported (prescription, over‐the‐counter, vitamin/herbal); potentially teratogenic medications listed; contraception use and method.ResultsMedication lists were completed for 437 of the 580 reproductive life plans reviewed (75%). Thirty‐five women (8%) reported use of a potentially teratogenic medication; most commonly reported agents included blood pressure medications and antidepressants. Only 10 women taking a potentially teratogenic medication (29%) reported using some form of contraception, half of which reported use of a less effective method such as condoms.ConclusionThe reproductive life plan can be a useful tool to identify women of childbearing age who require intervention due to use of potentially teratogenic medications. Efforts are needed to ensure complete and accurate reporting of medication use in reproductive life plans, and to promote effective contraceptive use among women taking potentially teratogenic medications.
A chronology of environmental changes in the Lake Vättern basin from deglaciation to its final isolation
Authors: Swärd Henrik , O'Regan Matt , Björck Svante , Greenwood Sarah L. , Kylander Malin E. , Mörth Carl‐Magnus , Pearce Christof , Jakobsson Martin 
Published: October 2017

During and after deglaciation, Lake Vättern developed from a proglacial lake situated at the westernmost rim of the Baltic Ice Lake (BIL), into a brackish water body connecting the North Sea and the Baltic Sea, and finally into an isolated freshwater lake. Here we present geochemical and mineralogical data from a 70‐m composite sediment core recovered in southern Lake Vättern. Together with a radiocarbon age model of this core, we are able to delineate the character and timing of the different lake stages. In addition to a common mineralogical background signature seen throughout the sediment core, the proglacial sediments bear a calcite imprint representing ice‐sheet transported material from the limestone bedrock that borders the lake basin in the northeast. The proglacial fresh to brackish water transition is dated to 11 480±290 cal. a BP and is in close agreement with other regional chronologies. The brackish period lasted c. 300 years and was followed by a c. 1600 year freshwater period before the Vättern basin became isolated from the Initial Littorina Sea. Decreasing detrital input, increasing δ13C values and the appearance of diatoms in the upper 15 m of the sediment succession are interpreted as an overall increase in biological productivity. This mode of sedimentation continues until the present and is interpreted to mark the final isolation of the lake at 9530±50 cal. a BP. Consequently, the isolation of Lake Vättern was not an outcome of the Ancylus Lake regression, but rather because of ongoing continental uplift in the early Littorina period.
Infant Visual Attention and Stimulus Repetition Effects on Object Recognition
Authors: Reynolds Greg D. , Richards John E. 
Published: October 2017

This study examined behavioral, heart rate (HR), and event‐related potential (ERP) correlates of attention and recognition memory for 4.5‐, 6‐, and 7.5‐month‐old infants (N = 45) during stimulus encoding. Attention was utilized as an independent variable using HR measures. The Nc ERP component associated with attention and the late slow wave (LSW) associated with recognition memory were analyzed. The 7.5‐month‐olds demonstrated a significant reduction in Nc amplitude with stimulus repetition. This reduction in Nc was not found for younger infants. Additionally, infants only demonstrated differential LSW amplitude based on stimulus type on attentive trials as defined by HR changes. These findings indicate that from 4.5 to 7.5 months, infants’ attentional engagement is influenced by an increasingly broader range of stimulus characteristics.
XEN‐45 collagen implant for the treatment of uveitic glaucoma
Authors: Sng Chelvin CA , Wang Jing , Hau Scott , Htoon Hla Myint , Barton Keith 
Published: October 2017

AbstractImportanceThe XEN‐45 implant, a hydrophilic collagen implant which drains aqueous to the subconjunctival space, has not been investigated in the context of uveitic glaucoma.BackgroundTo determine the safety and efficacy of the XEN‐45 collagen implant in eyes with uveitic glaucoma.DesignExploratory prospective case series.Participantspatients with medically uncontrolled uveitic glaucoma.MethodsTwenty‐four consecutive patients (mean age ± standard deviation [SD] = 45.3 ± 18.1 years) were implanted with the XEN‐45 implant.Main Outcome MeasuresThe primary outcome measure was intraocular pressure (IOP) reduction at 12 months as compared to baseline. Secondary outcome measures included ocular hypotensive medication use at 12 months, the requirement for further glaucoma surgery and failure. Intraoperative and postoperative complications were documented.ResultsThe baseline mean ± SD IOP was 30.5 ± 9.8 mmHg and the mean ± SD number of glaucoma medications required was 3.3 ± 0.8. In 20 eyes (83.3%) in whom conventional glaucoma surgery was originally perceived to be inevitable, further surgery was not required after XEN‐45 implantation. The mean IOP was reduced by 60.2% from baseline to 12.2 ± 3.1 mmHg and mean medication usage was reduced to 0.4 ± 0.9 at 12 months (both P < 0.001). One patient had hypotony persisting beyond 2 months that required surgical revision and one patient developed blebitis. The 12‐month cumulative Kaplan–Meier survival probability was 79.2%.Conclusions and RelevanceThe XEN‐45 implant is effective for the treatment of patients with medically uncontrolled uveitic glaucoma. Potentially sight‐threatening complications, including bleb‐related ocular infection and persistent hypotony, may occur.
Predicting chronic neglect: Understanding risk and protective factors for CPS‐involved families
Authors: Logan‐Greene Patricia , Semanchin Jones Annette 
Published: October 2017

AbstractChild neglect continues to receive less attention in research literature compared to other forms of maltreatment, despite accumulating evidence of serious negative impacts on child well‐being. Chronic neglect is also poorly understood. Although such cases comprise a relatively small percentage of workers' caseloads, they represent accumulation of harm that impacts the cognitive and social development of children. These cases can also disproportionately utilize protective service resources. This study contributes to the literature by examining risk and protective factors of chronic neglect. We utilized administrative data (N = 2,074) from a midsize city in the Northeast to examine the use of existing risk assessment tools to distinguish families with and without chronic neglect, including an analysis of the predictive capacity of risk and protective factors. We found that families with chronic neglect were younger, had more children, were more likely to have children under age one, and had higher rates of domestic violence, mental health problems, and cognitive impairment. None of the assessed protective factors differed significantly. The overall predictive value of the assessment was low. Implications include the need to expand risk assessment tools to incorporate patterns over time and identify early indicators specific to chronic neglect.
Enlarged perivascular spaces are associated with health‐related quality of life in patients with acute ischemic stroke
Authors: Liang Yan , Deng Min , Chen Yang‐Kun , Mok Vincent , Wang De‐Feng , Ungvari Gabor S. , Chu Chiu‐Wing Winnie , Berge Eivind , Tang Wai‐Kwong 
Published: October 2017

SummaryAimsThis study explored the association between enlarged perivascular spaces (EPVS) and the health‐related quality of life (HRQoL) in patients with acute ischemic stroke.MethodsThis was an observational study of consecutively screened patients with acute ischemic stroke from March 2010 to March 2015. EPVS were rated in the basal ganglia and the centrum semiovale with a validated scale. The HRQoL was assessed 3 months after the stroke onset using the Stroke‐Specific Quality of Life (SSQoL). Linear regression models were used to study the association between EPVS and HRQoL.ResultsThe study included 648 patients (mean age 65.8 years; 40.0% women) with mild to moderately severe stroke (median NIHSS score 2), of whom 640 (98.8%) exhibited signs of small vessel disease. The median EPVS scores in the basal ganglia and the centrum semiovale were 1 each. In linear regression analysis, EPVS in the basal ganglia were associated with a lower total SSQoL score (P = 0.02) and lower mobility (P = 0.01), mood (P = 0.03), and self‐care (P < 0.01). EPVS in the centrum semiovale were associated only with a lower SSQoL work/productivity subscore (P = 0.002).ConclusionsEPVS are associated with lower HRQoL in patients with mild to moderate acute ischemic stroke. Early identification and intervention of EPVS may improve HRQoL in stroke survivors.
Influence of backside loading on the floating mass transducer: An in vitro experimental study
Authors: Gostian A.‐O. , Otte M.S. , Pazen D. , Ortmann M. , Schwarz D. , Hüttenbrink K.B. , Beutner D. 
Published: October 2017

HypothesisThe vibration of the floating mass transducer (FMT) of a single active middle‐ear implant (AMEI) is distinctly influenced by the properties of the material coupled to its back side.BackgroundIn round window vibroplasty, the FMT needs to be padded against the surrounding bone opposite from the round window membrane. This represents one factor influencing its performance as a round window driver. Therefore, we examined the effects of different materials linked to the back side of an FMT on its vibration range.MethodsThe back side of an FMT was glued to a silicone cylinder 1.0 mm in diameter and 1.0 mm – 1.5 mm in length and of 40A, 50A or 70A Shore hardness; to cartilage of equivalent size; or to a round window soft coupler (RWSC), all firmly fixed on a steel plate. The vibrations were determined by a laser Doppler vibrometer (LDV) measuring the velocity of the centre point on the front side of the FMT.ResultsThe materials on the back side of the FMT significantly influenced the vibration range of the FMT. The RWSC and silicone of 40A Shore hardness allowed for the highest detected velocities, while cartilage led to a distinct reduction similarly to 70A silicone.ConclusionThe coupling on the back side of an FMT distinctly affects its vibration range. In this regard, the RWSC and silicone of 40A Shore hardness yield the least impairment of vibration. Thus, the RWSC may be a feasible option in round window vibroplasty when additionally connected to the FMT opposite from the round window membrane.
Views of diverse primary care patients on the roles of healthcare providers and staff and the influence of other variables in their weight management
Authors: Tucker C. M. , Williams J. L. , Wippold G. M. , Bilello L. A. , Morrissette T. A. , Good A. J. , Shah N. R. , Rowland N. E. 
Published: October 2017

SummaryThe prevalence of overweight/obesity is disproportionately higher among racial/ethnic minority and low‐income patients. The purpose of this study was to survey racially diverse, low‐income patients regarding their experiences with and desires regarding their providers’ involvement in weight management. Adult patients (N = 529), including mostly African American (42.7%), White (44.6%) and low‐income (55.5% with incomes <$30 000) patients from 7 Patient‐Centered Medical Homes voluntarily completed a brief anonymous survey while waiting to see their providers. Only 19.8% of the patients said that their primary care provider frequently or very frequently talked with them about their weight. Older patients as compared to younger patients, as well as males compared to females, were more likely to have their primary care provider talk to them about their diet and physical activity during the last year. It was also found that 56.9% of the patients were interested in getting help from their doctor to connect with resources for weight management in their community. African American patients, as compared to White patients, were more interested in getting such help. These results suggest that there is a need to establish healthcare policies and training in primary care settings that are designed to ensure that primary care providers routinely talk with all of their patients, including their female and older patients, about their weight and weight management services. Additionally, primary care administrators need to play an increased role in identifying, developing, and advocating for affordable weight management services, particularly in African American and low‐income communities.
Analysis of the clinical features of invasive bronchopulmonary aspergillosis
Authors: Cao Yueqin , Shao Changzhou , Song Yuanlin 
Published: October 2017

AbstractIntroductionEarly diagnosis of invasive bronchopulmonary aspergillosis (IBPA) is difficult, so the mortality rate is high.ObjectiveTo discuss the clinical features of IBPA.MethodsWe retrospectively analyzed the clinical features, imaging findings, laboratory test, diagnosis and treatment of 115 patients with IBPA diagnosed from October 2004 to June 2013 in Zhongshan Hospital, Fudan University.ResultsThe main clinical manifestations were cough in 58 patients (50.4%), expectoration in 37 patients (32.2%), fever in 18 patients (15.7%), shortness of breath in 26 patients (22.6%), hemoptysis in 26 patients (22.6%) and chest pain in 7 patients (6.0%). The main CT findings were nodules in 35 patients (30.4%), consolidation shadows or patchy shadows in 62 patients (53.9%) and cavity in 14 patients (12.2%). Percutaneous pulmonary biopsy was conducted in 25 patients (21.7%), TBLB in 58 patients (50.4%) and thoracoscopic surgery in 32 patients (27.8%). The positive rate of GM test was 73.5% (72/98). Thirty patients who received lobectomy were followed up for 1‐3 years. Fifty‐five patients who received monotherapy with antifungal agents were followed up for 1‐3 years, and 12 patients were healed. The lesions for 23 patients were obviously absorbed, 10 patients had aggravation and two patients died.ConclusionsThe clinical manifestations of IBPA were unspecific. The main symptoms were cough and expectorate. Patients with different immunologic function had different imaging findings. The halo sign and new moon sign for diagnosis was not as common as reported. Interventional therapy under bronchoscope is very important for patients with ATB.
Evaluation of adherence and tolerability of prolonged‐release tacrolimus (Advagraf™) in kidney transplant patients in Germany: A multicenter, noninterventional study
Authors: Lehner Lukas J. , Reinke Petra , Hörstrup Jan H. , Rath Thomas , Suwelack Barbara , Krämer Bernhard K. , Budde Klemens , Banas Bernhard 
Published: October 2017

AbstractThis study assessed adherence to prolonged‐release tacrolimus (PR‐T)‐based immunosuppression during routine maintenance of renal transplant recipients in Germany. Patients had received PR‐T for ≥1 month at inclusion. Data were collected during four visits (V): baseline (V1), 6 (V2), 12 (V3), and 18 (V4) months. Composite primary endpoint: nonadherence at V4, defined as self‐reported nonadherence on the Basel Assessment of Adherence with Immunosuppressive Medication Scale (BAASIS©), investigator‐rated nonadherence, and/or V4 tacrolimus trough level outside a predefined range. Secondary endpoints: individual BAASIS items, incidence of rejection, kidney function, and safety. Overall, 153 adult kidney recipients (mean [standard deviation] time post‐transplant 5.8 [4.6] years) were included. Nonadherence was high at V4 (67.7% [95% confidence interval 58.9%, 75.6%]). Medication‐taking adherence was 86.9% and 91.3% at V1 and V4, respectively; adherence to timing of medication intake was 58.2% and 58.3%, with little evidence of missed doses/drug holidays. Investigators rated adherence “good” in 85.6% of patients (V4). Two (1.3%) patients had acute rejection episodes. Kidney function remained stable (mean creatinine clearance, V1: 62.1 mL/min; V4: 65.3 mL/min). Investigators rated effectiveness of PR‐T as “very good”/“good” in 91.5% of patients. Most patients (94.7%) found PR‐T dosing more convenient than immediate‐release tacrolimus. PR‐T was well tolerated with high medication persistence.
Exploring opportunities to support mental health care using social media: A survey of social media users with mental illness
Authors: Naslund John A. , Aschbrenner Kelly A. , McHugo Gregory J. , Unützer Jürgen , Marsch Lisa A. , Bartels Stephen J. 
Published: October 2017

AimSocial media holds promise for expanding the reach of mental health services, especially for young people who frequently use these popular platforms. We surveyed social media users who self‐identified as having a mental illness to learn about their use of social media for mental health and to identify opportunities to augment existing mental health services.MethodsWe asked 240 Twitter users who self‐identified in their profile as having a mental illness to participate in an online survey. The survey was in English and inquired about participants’ mental health condition, use of social media for mental health and interest in accessing mental health programs delivered through social media.ResultsRespondents from 10 countries completed 135 surveys. Most respondents were from the United States (54%), Canada (22%) and the United Kingdom (17%) and reported a psychiatric diagnosis of either schizophrenia spectrum disorder (27%), bipolar disorder (25%), major depressive disorder (16%) or depression (20%). Young adults age ≤35 (46%) were more likely to use Instagram (P = .002), Snapchat (P < .001) and their mobile phone for accessing social media (P < .001) compared to adults age 36 and older (53%). Most participants (85%) expressed interest in mental health programs delivered through social media, especially to promote overall health and wellbeing (72%) and for coping with mental health symptoms (90%).ConclusionsThis exploratory study demonstrates the feasibility of reaching social media users with mental illness and can inform efforts to leverage social media to make evidence‐based mental health services more widely available to those in need.
Cortical superficial siderosis and acute convexity subarachnoid hemorrhage in cerebral amyloid angiopathy
Authors: Raposo N. , Calviere L. , Cazzola V. , Planton M. , Patsoura S. , Wargny M. , Albucher J. F. , Sommet A. , Olivot J. M. , Chollet F. , Pariente J. , Bonneville F. , Viguier A. 
Published: October 2017

Background and purposeAcute convexity subarachnoid hemorrhage (cSAH) and cortical superficial siderosis (cSS) are neuroimaging markers of cerebral amyloid angiopathy (CAA) that may arise through similar mechanisms. The prevalence of cSS in patients with CAA presenting with acute cSAH versus lobar intracerebral hemorrhage (ICH) was compared and the physiopathology of cSS was explored by examining neuroimaging associations.MethodsData from 116 consecutive patients with probable CAA (mean age, 77.4 ± 7.3 years) presenting with acute cSAH (n = 45) or acute lobar ICH (n = 71) were retrospectively analyzed. Magnetic resonance imaging scans were analyzed for cSS and other imaging markers. The two groups’ clinical and imaging data were compared and the associations between cSAH and cSS were explored.ResultsPatients with cSAH presented mostly with transient focal neurological episodes. The prevalence of cSS was higher amongst cSAH patients than amongst ICH patients (88.9% vs. 57.7%; P < 0.001). In multivariable logistic regression analysis, focal [odds ratio (OR) 6.73; 95% confidence interval (CI) 1.75–25.81; P = 0.005] and disseminated (OR 11.68; 95% CI 3.55–38.35; P < 0.001) cSS were independently associated with acute cSAH, whereas older age (OR 0.93; 95% CI 0.87–0.99; P = 0.025) and chronic lobar ICH count (OR 0.45; 95% CI 0.25–0.80; P = 0.007) were associated with acute lobar ICH.ConclusionsAmongst patients with CAA, cSS is independently associated with acute cSAH. These findings suggest that cSAH may be involved in the pathogenesis of the cSS observed in CAA. Longitudinal studies are warranted to assess this potential causal relationship.