bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systemic, Ocular and Genetic Risk Factors for Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy in Singaporeans
Authors: Cheung Chui Ming Gemmy , Laude Augustinus , Yeo Ian , Tan Shu-Pei , Fan Qiao , Mathur Ranjana , Lee Shu Yen , Chan Choi Mun , Tan Gavin , Lim Tock Han , Cheng Ching-Yu , Wong Tien Yin 
Published: January 2017

AbstractTo examine the association of systemic, ocular and genetic risk factors in neovascular age-related macular degeneration (nAMD) in a large cohort of Asian patients, and to further compare risk factors between those with typical AMD and polypoidal choroidal vasculoapthy (PCV) subtypes. We recruited 456 cases and 1,824 controls matched for age, gender and ethnicity. Data on systemic and ocular risk factors were collected on questionnaires. In a subgroup of subjects, we included genetic data on four AMD-associated single nucleotide polymorphisms (SNPs). Risk factors for nAMD and subtypes were analyzed. Systemic risk factors for nAMD included older age, male gender, higher BMI and higher HDL-cholesterol. Ocular risk factors included pseudophakic and shorter axial length. Risk factors common to both typical AMD and PCV subtypes included age, BMI and HDL-cholesterol. Shorter axial length was only associated with PCV, while male gender and pseudophakia were only associated with typical AMD. In the subgroup with genotype data, ARMS2 rs10490924 and CFH rs800292 were associated with nAMD. None of the risk factors were significantly different between PCV and typical AMD. Systemic, ocular and genetic risk factors were largely similar for typical AMD and PCV subtypes in this Asian population based in Singapore.
Excellent Thermoelectric Properties in monolayer WSe2 Nanoribbons due to Ultralow Phonon Thermal Conductivity
Authors: Wang Jue , Xie Fang , Cao Xuan-Hao , An Si-Cong , Zhou Wu-Xing , Tang Li-Ming , Chen Ke-Qiu 
Published: January 2017

AbstractBy using first-principles calculations combined with the nonequilibrium Green’s function method and phonon Boltzmann transport equation, we systematically investigate the influence of chirality, temperature and size on the thermoelectric properties of monolayer WSe2 nanoribbons. The results show that the armchair WSe2 nanoribbons have much higher ZT values than zigzag WSe2 nanoribbons. The ZT values of armchair WSe2 nanoribbons can reach 1.4 at room temperature, which is about seven times greater than that of zigzag WSe2 nanoribbons. We also find that the ZT values of WSe2 nanoribbons increase first and then decrease with the increase of temperature, and reach a maximum value of 2.14 at temperature of 500 K. It is because the total thermal conductance reaches the minimum value at 500 K. Moreover, the impact of width on the thermoelectric properties in WSe2 nanoribbons is not obvious, the overall trend of ZT value decreases lightly with the increasing temperature. This trend of ZT value originates from the almost constant power factor and growing phonon thermal conductance.
Komplikationen bei rheumachirurgischen Eingriffen der Schulter
Authors: Schmidt Klaus 
Published: January 2017

ZusammenfassungDas Schultergelenk ist bei der rheumatoiden Arthritis häufig mitbefallen. Aufgrund seines komplexen Aufbaus führt der rheumatische Befall früh zu Funktionsstörungen, die aber subjektiv oft erst spät empfunden werden. Arthroskopische Eingriffe weisen eine geringe Komplikationsrate auf. Rotatorenmanschettenrekonstruktionen führen aufgrund der rheumatisch bedingten Veränderungen des Muskel- und Sehnengewebes häufig zu Rerupturen. Die endoprothetische Versorgung wird bei der rheumatisch stark veränderten Schulter durch die entzündlichen Gewebsveränderungen erschwert. Periprothetische Frakturen treten aufgrund der verminderten Knochenqualität auf und sind nur erschwert osteosynthetisch zu versorgen. Multipler Gelenkersatz erfordert hierbei mitunter individuelle Lösungsmöglichkeiten. Protheseninfekte an der Schulter sind schwerwiegende Komplikationen und bedürfen einer frühzeitigen Diagnosestellung und operativer Revision.
Kant and thought insertion
Authors: Golob Sacha 
Published: January 2017

AbstractThis article examines the phenomenon of thought insertion, one of the most extreme disruptions to the standard mechanisms for self-knowledge, in the context of Kant’s philosophy of mind. This juxtaposition is of interest for two reasons, aside from Kant’s foundational significance for any modern work on the self. First, thought insertion presents a challenge to Kant’s approach. For example, the first Critique famously held that “The ‘I think’ must be able to accompany all my representations” (Kant, KrV, B132). Yet thought insertion raises the problem of representations that are “mine” by many natural criteria, and yet which I am unwilling to self-ascribe. Ultimately, my argument will be that thought insertion simultaneously problematises, and yet to some degree also vindicates, the complex distinctions between activity and passivity that underlie Kant’s system. Second, I argue that Kant’s position contains resources that allow us to model thought insertion, and its broader implications for self-knowledge, in an interesting and distinctive manner. Kant himself held an extreme view of philosophy’s competence in the study of mental disorder: in the Anthropology, he suggests that courts must refer such cases to philosophers, rather than medics (Kant, Anth, p. 214). My aim is much more modest: to suggest that a Kantian treatment of thought insertion deserves consideration by both philosophers and clinicians. This article is published as part of a collection on self-knowledge in and outside of illness.
Superresolution imaging reveals activity-dependent plasticity of axon morphology linked to changes in action potential conduction velocity
Authors: Chéreau Ronan , Saraceno G. Ezequiel , Angibaud Julie , Cattaert Daniel , Nägerl U. Valentin 
Published: January 2017

SignificanceRecent work has called into question the classic view of axons as electroanatomical cables that faithfully transmit nerve impulses in an all-or-none fashion over variable distances. Because of their small size, below the diffraction barrier of light microscopy, it has not been possible to resolve their dynamic morphology in living brain tissue. Enabled by a combination of live-cell superresolution stimulated emission depletion (STED) microscopy, electrophysiology, and mathematical modeling, we show here that high-frequency action potential firing induces structural enlargement of boutons and axon shafts in hippocampal brain slices, which in turn drives changes in the conduction velocity of nerve impulses (action potentials). The findings reveal a mechanism for tuning the timing of communication between nerve cells.
An experimental analysis of acquired impulse control among adult humans intolerant to alcohol
Authors: Wang Jianxin , Rao Yulei , Houser Daniel E. 
Published: January 2017

SignificanceWe find that alcohol intolerance, which occurs randomly and leads affected people systematically to resist the impulse to consume alcohol, enables improved impulse control in another behavioral domain. Our findings show that impulse control can develop in adult populations as a result of exercising routine behaviors in naturally occurring environments. This finding is important because the ability to control tempting impulses significantly impacts the health and well-being of people at all ages. Our findings complement theory by providing rigorous empirical evidence that simple lifestyle changes may have significant personal well-being benefits. In particular, small acts of self-control, such as resisting drinking or always waking at the same time, can increase one’s overall ability to resist selfish temptations.
Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis
Authors: Zhang Hui , Watanabe Ryu , Berry Gerald J. , Vaglio Augusto , Liao Yaping Joyce , Warrington Kenneth J. , Goronzy Jörg J. , Weyand Cornelia M. 
Published: January 2017

Significance
Antigen recognition by the immune system triggers rapid, specific, and protective responses, which are counterbalanced by inhibitory checkpoints to minimize potentially harmful immunity. The programmed death-1/ programmed death ligand-1 (PD-1/PD-L1) checkpoint is overreactive in cancer patients, curbing antitumor immunity. Whether a failing PD-1/PD-L1 checkpoint contributes to spontaneous autoimmune disease in humans is unknown. Here, we found that in patients with the autoimmune vasculitis giant cell arteritis, antigen-presenting cells provide insufficient negative signaling; unleashing highly activated T cells to infiltrate and damage the walls of large arteries. Thus, immunoinhibitory signals protect large arteries against inflammatory attack and checkpoint activation may be a suitable strategy to treat autoimmune vasculitis.
Effect of a fish stock's demographic structure on offspring survival and sensitivity to climate
Authors: Stige Leif Christian , Yaragina Natalia A. , Langangen Øystein , Bogstad Bjarte , Stenseth Nils Chr. , Ottersen Geir 
Published: January 2017

SignificanceIt is feared that loss of old and large spawners impairs heavily fished fish stocks’ reproductive capacity and increases their sensitivity to environmental fluctuations. The Barents Sea cod is the world’s largest cod stock and has been reported to show increased temperature–recruitment associations in periods with predominantly young and small spawners. We here investigate the possible causal basis for the link between demographic structure and recruitment by analyzing long-term egg survey data. Results support a link between demographic structure and abundance and distributional extent of eggs but not between egg distribution and recruitment. These results question whether the benefits of a wide spatiotemporal distribution of spawning are of quantitative importance for recruitment.
The syntactic realisation of complex events and complex predicates in situations of Irish
Authors: Nolan Brian 
Published: January 2017

Abstract
This chapter is concerned with the nature of complex events and complex predicates in Irish. We characterise the framing of complex events within a situation. A situation is considered to be a structured entity with certain attributes that serves as a unifying device to link semantics to events through to syntax. Through the perspective of a situation, we view the set of relationships between multi-verb constructions, single and multiple clauses, and a variety of complex events. In a sentence or clause with multiple verbs, the multiple verbs are argued to represent individual discrete events characterised in some relation of significance and conceptualised as forming a cognitive unit with significant syntactic consequences for argument realisation and argument sharing. Using Irish data, within a situation we examine and characterise multiple events where the events are in a transition from e1 into e2, in sequence where e1 occurs before e2, and simultaneous events occurring together where e1 and e2 unfold at the same time. We also characterise complex predication where the multi-verb single clause realises a single event in syntax but additionally denotes the phase of the event. We find that a multi-verb single clause can encode causation or certain adverbial-like functions such as modulating manner, means, path or trajectory of the event.
Serial verb constructions and event structure representations
Authors: Riccio Anna 
Published: January 2017

Abstract
A survey of the relevant literature on serial verb constructions (SVCs) shows that the label ‘SVC’ is often used as an umbrella term that inappropriately encompasses various verb phrase sequences which are essentially different from traditional SVCs. The aim of this chapter is to highlight and discuss some syntactic and semantic characteristics of SVCs, which researchers have described over the years, within the syntax-semantics interface developed by the Role and Reference Grammar (RRG) framework (Van Valin & LaPolla 1997; Van Valin 2005). The resulting analysis demonstrates that RRG provides a useful theoretical perspective able to embody the peculiarities of traditional SVCs, by distinguishing them from other multi-verb constructions that in the relevant literature are often classified as members of the SVC category.1
Feelings as emotion, attitude, and viewpoints
Authors: Guerrero Lilián , Domínguez Irasema Cruz 
Published: January 2017

Abstract
This chapter examines the syntax and semantics of sentir ‘to feel’ in simple and complex structures. Based on data from Mexican Spanish, we corroborate the polysemy of this verb, and we point out that different complement types (and verb forms) denote particular subjective connotations (emotions, attitudes, thoughts, evaluations, viewpoints). We propose that nominal complements correlate with an unmediated physical and emotional perception of an object, while clausal complements report a thought towards a proposition. What we called predicative elements (mainly adjectives and past participles) describe the state, quality, or property of the perceived object. In the last structure, the verb form is sentirse, and both the verb and the perceived state form a complex predicate.
Nominal predication in Persian
Authors: Saeedi Zari 
Published: January 2017

Abstract
The present study explores the nominal complex predicates (CPs) in Persian, one of the oldest Indo-European languages with 2500 years of written history (Khanlari 1979), where a noun fuses with the impoverished form of the verb referred to as ‘light verb’ (Cattell 1984). The framework adopted is Role and Reference Grammar (RRG) theory (Van Valin & LaPolla 1997; Van Valin 2005, 2010). Following Saeedi (2009a), the paper analyzes these nominal CPs or nuclear junctures (NJs) (in RRG’s term) with regard to their argument structure. The findings indicate that the nominal constituent being of concrete, abstract, action, and process type plays an important role in determining the Aktionsart type of the juncture.
Early Detection of Nonnative Alleles in Fish Populations: When Sample Size Actually Matters
Authors: Della Croce Patrick , Poole Geoffrey C. , Payn Robert A. , Gresswell Robert E. 
Published: January 2017

Abstract
Reliable detection of nonnative alleles is crucial for the conservation of sensitive native fish populations at risk of introgression. Typically, nonnative alleles in a population are detected through the analysis of genetic markers in a sample of individuals. Here we show that common assumptions associated with such analyses yield substantial overestimates of the likelihood of detecting nonnative alleles. We present a revised equation to estimate the likelihood of detecting nonnative alleles in a population with a given level of admixture. The new equation incorporates the effects of the genotypic structure of the sampled population and shows that conventional methods overestimate the likelihood of detection, especially when nonnative or F-1 hybrid individuals are present. Under such circumstances—which are typical of early stages of introgression and therefore most important for conservation efforts—our results show that improved detection of nonnative alleles arises primarily from increasing the number of individuals sampled rather than increasing the number of genetic markers analyzed. Using the revised equation, we describe a new approach to determining the number of individuals to sample and the number of diagnostic markers to analyze when attempting to monitor the arrival of nonnative alleles in native populations.
Blue and Red Voices: Effects of Political Ideology on Consumers’ Complaining and Disputing Behavior
Authors: Jung Kiju , Garbarino Ellen , Briley Donnel A , Wynhausen Jesse 
Published: January 2017

Abstract
Political ideology plays a pivotal role in shaping individuals’ attitudes, opinions, and behaviors. However, apart from a handful of studies, little is known about how consumers’ political ideology affects their marketplace behavior. The authors used three large consumer complaint databases from the Consumer Financial Protection Bureau, National Highway Traffic Safety Administration, and Federal Communications Commission in conjunction with a county-level indicator of political ideology (the 2012 US presidential election results) to demonstrate that conservative consumers are not only less likely than liberal consumers to report complaints but also less likely to dispute complaint resolutions. A survey also sheds light on the relationship between political ideology and complaint/dispute behavior. Due to stronger motivations to engage in “system justification,” conservative (as opposed to liberal) consumers are less likely to complain or dispute. The present research offers a useful means of identifying those consumers most and least likely to complain and dispute, given that political ideology is more observable than most psychological factors and more stable than most situational factors. Furthermore, this research and its theoretical framework open opportunities for future research examining the influence of political ideology on other marketplace behaviors.
Insights into nurses’ work: Exploring relationships among work attitudes and work-related behaviors
Authors: Perreira Tyrone , Berta Whitney , Ginsburg Liane , Barnsley Jan , Herbert Monique 
Published: January 2017

Background:Work attitudes have been associated with work productivity. In health care, poor work attitudes have been linked to poor performance, decreased patient safety, and quality care. Hence, the importance, ascribed in the literature, of work that clearly identifies the relationships between and among work attitudes and work behaviors linked to performance.Purpose:The purpose of this study is to better understand the relationships between work attitudes—perceived organizational justice, perceived organizational support (POS), affective commitment—consistently associated with a key type of performance outcome among nurses’ organizational citizenship behaviors (OCBs).Methodology:A survey was developed and administered to frontline nurses working in the province of Ontario, Canada. Data analysis used path analytic techniques.Results:Direct associations were identified between interpersonal justice and POS, procedural justice and POS, and POS and affective commitment to both one’s supervisor and one’s co-workers. Affective commitment to patients and career was directly associated with OCBs. Affective commitment to one’s co-worker was directly associated with OCBs directed toward individuals, as affective commitment to one’s organization was with OCBs directed toward the organization. Finally, OCBIs and OCBs were directly associated.Conclusions:Examining the relationships of these constructs in a single model is novel and provides new information regarding their complexity. Findings suggest that prior approaches to studying these relationships may have been undernuanced, and conceptualizations may have led to somewhat inaccurate conclusions regarding their associations.Practice Implications:With limited resources, knowledge of nurse work attitudes can inform human resource practices and operational policies involving training programs in employee communication, transparency, interaction, support, and performance evaluation.
One Hundred Years of Psychiatry at Johns Hopkins
Authors: DePaulo J. Raymond 
Published: January 2017

Abstract
This article describes a history of clinical methods and constructs that guide Psychiatry at Johns Hopkins Phipps Clinic today. The contributions of Adolf Meyer and Paul McHugh are central and closely connected. Both emphasize the clinical examination as the central practice of psychiatry as a specialty within medicine. Meyer's comprehensive examination of the patient became the centerpiece of his approach and was the standard for psychiatrists in the English-speaking world. McHugh, with Phillip Slavney, developed a pluralistic and practical framework for interpreting that history and examination. Both argued against the uncritical use of the modern disease construct. McHugh argues that the disease construct, although fundamental, is but one of four useful “perspectives of psychiatry” and is, thus, an insufficient basis for psychiatric practice. The perspectives could be used as an organizing framework by all physicians who seek a practical and truly personalized approach to the care of patients.
Emergency Department Care of Young Children at Risk for Traumatic Brain Injury
Authors: Reilly Caroline , Zhang Nanhua , Babcock Lynn , Wade Shari L. , Rhine Tara 
Published: January 2017

Objectives
The aims of the study were to describe emergency department (ED) management of young children with head injury and to assess parental comfort level and perceptions of ED care.

Methods
This was a prospective observational study of children younger than 5 years who presented to a pediatric ED after head injury. Children were eligible if clinical observation was an appropriate ED management option per the Pediatric Emergency Care Academic Research Network's neuroimaging clinical decision rule. Demographics, injury variables, and ED clinician surveys explaining the care provided were collected at time of study enrollment. Parents were subsequently contacted to assess understanding of ED management and comfort with care.

Results
One hundred four children were enrolled with a mean (standard deviation) age of 1.19 (1.34) years. Thirty (29%) had emergent neuroimaging and 59 (57%) were placed into a period of observation per clinician report. A total of 37 children received a head computed tomography, of which 21 (57%) were normal. Eighty-four parents (81%) completed the phone follow-up. Of these children, there was a significant difference between whether parents and clinicians reported that the child had been clinically observed in the ED (P < 0.0001). Parents of children who did not receive a head CT were more likely to be uncomfortable with the decision to obtain neuroimaging compared with those who did receive a head CT (P = 0.003).

Conclusions
Parents are not always comfortable with the medical care practices provided and are often unaware of clinical observation when it does occur. Better parent-clinician communication could improve parental understanding and reduce overall discomfort.
Respiratory pathogen panels in the hospital: good or unnecessary?
Authors: Cawcutt Kelly A. , Fey Paul D. , Kalil Andre C. 
Published: January 2017

Purpose of review
We aim to review the epidemiology of respiratory viral infections and the strengths and limitations of multiplex respiratory pathogen panels that are currently available along with their respective features and differences.

Recent findings
We give particular emphasis to the pathogens included on each test and evaluate their performance in the hospital setting.

Summary
We conclude with a discussion on the evidence for the clinical utility of respiratory pathogen multiplex panels in hospitalized patients, including the potential for coinfection with viral and bacterial pathogens.