bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modifiable Risk Factors for Delirium in Critically Ill Trauma Patients: A Multicenter Prospective Study
Authors: Duceppe Marc-Alexandre , Williamson David R. , Elliott Audrée , Para Mélissa , Poirier Marie-Christine , Delisle Marie-Soleil , Deckelbaum Dan , Razek Tarek , Desjardins Monique , Bertrand Jean-Claude , Bernard Francis , Rico Philippe , Burry Lisa , Frenette Anne Julie , Perreault Marc 
Published: March 2017

Objective: Intensive care unit (ICU)–acquired delirium has been associated with increased morbidity and mortality. Prevention strategies including modification of delirium risk factors are emphasized by practice guidelines. No study has specifically evaluated modifiable delirium risk factors in trauma ICU patients. Our goal was to evaluate modifiable risk factors for delirium among trauma patients admitted to the ICU. Design: Prospective observational study. Setting: Two level 1 trauma ICU centers. Patients: Patients 18 years of age or older admitted for trauma including mild to moderate traumatic brain injury were eligible for the study. Interventions and Measurements: Delirium was assessed daily using the confusion assessment method for the ICU (CAM-ICU). The effect of modifiable risk factors was assessed using multivariate Cox regression analysis adjusting for severity of illness and significant nonmodifiable risk factors. Main Results: A total of 58 of 150 recruited patients (38.7%; 95% confidence interval [CI] 30.9-46.5) screened positive for delirium during ICU stay. When adjusting for significant nonmodifiable risk factors, physical restraints (hazard ratio [HR]: 2.13; 95% CI: 1.07-4.24) and active infection or sepsis (HR: 2.12; 95% CI: 1.18-3.81) significantly increased the risk of delirium, whereas opioids (HR: 0.35; 95% CI: 0.13-0.98), episodes of hypoxia (HR: 0.55; 95% CI: 0.31-0.95), access to a television/radio in the room (HR: 0.26; 95% CI: 0.11-0.62), and number of hours mobilized per day (HR: 0.77; 95% CI: 0.68-0.88) were associated with significantly less risk of delirium. Conclusion: We have identified modifiable risk factors for delirium. Future studies should aim at implementing strategies to modify these risk factors and evaluate their impact on the risk of delirium.
Statistical analysis plan for the Head Position in Stroke Trial (HeadPoST): An international cluster cross-over randomized trial
Authors: Billot Laurent , Woodward Mark , Arima Hisatomi , Hackett Maree L , Muñoz Venturelli Paula , Lavados Pablo M , Brunser Alejandro , Peng Bin , Cui Liying , Song Lily , Heritier Stephane , Jan Stephen , Middleton Sandy , Olavarría Verónica V , Lim Joyce , Robinson Thompson , Pontes-Neto Octavio , Watkins Caroline , Anderson Craig S 
Published: March 2017

Background There is evidence to indicate that the lying flat head position increases cerebral blood flow and oxygenation in patients with acute ischemic stroke, but how these physiological effects translate into clinical outcomes is uncertain. The Head Position in Stroke Trial aims to determine the comparative effectiveness of lying flat (0°) compared to sitting up (≥30°) head positioning, initiated within 24 h of hospital admission for patients with acute stroke. Design An international, pragmatic, cluster-randomized, crossover, open, blinded outcome assessed clinical trial. Each hospital with an established acute stroke unit (cluster) site was required to recruit up to 140 consecutive cases of acute stroke (one phase of head positioning before immediately crossing over to the other phase of head positioning), including both acute ischemic stroke and intracerebral hemorrhage, in each randomized head position as a ‘business as usual’ policy. Objective To outline in detail the predetermined statistical analysis plan for the study. Methods All accumulated data will be reviewed and formally assessed. Information regarding baseline characteristics of patients, their process of care and management will be outlined, and for each item, statistically relevant descriptive elements will be described. For the trial outcomes, the most appropriate statistical comparisons are described. Results A statistical analysis plan was developed that is transparent, verifiable, and predetermined before completion of data collection. Conclusions We developed a predetermined statistical analysis plan for Head Position in Stroke Trial to avoid analysis bias arising from prior knowledge of the findings, in order to reliably quantify the benefits and harms of lying flat versus sitting up early after the onset of acute stroke. Trial registration ClinicalTrials.gov identifier NCT02162017; ANZCTR identifier ACTRN12614000483651
Exceeding Pitch Count Recommendations in Little League Baseball Increases the Chance of Requiring Tommy John Surgery as a Professional Baseball Pitcher
Authors: Erickson Brandon J. , Chalmers Peter N. , Axe Michael J. , Romeo Anthony A. 
Published: March 2017

Background: Empirical evidence has suggested a connection between youth pitch counts and subsequent elbow injury. For players within the Little League World Series (LLWS), detailed historical player data are available. Some of these players progress to both professional play and require an ulnar collateral ligament reconstruction (UCLR). Purpose: To determine the percentage of LLWS pitchers who proceed to play professional (major or minor league) baseball, the rate of UCLR in former LLWS pitchers who played professional baseball, and the risk to those who exceeded current pitch count recommendations while playing in the LLWS. Study Design: Cohort study; Level of evidence, 3. Methods: All LLWS pitchers from 2001 through 2009 from all teams and countries were identified, and all performance data were extracted. A professional (major and minor league) baseball database was then searched to determine whether each former LLWS pitcher played professional baseball. These professional players were then searched for using publicly available databases to determine whether they underwent UCLR. Results: Overall, 638 adolescents pitched in the LLWS between 2001 and 2009; 62 (10%) progressed to professional play. Of the 56 minor league players, 25 (45%) pitched. Of the 6 Major League Baseball players, 3 (50%) pitched. Three former LLWS pitchers (5%) who played professionally underwent UCLR. In former LLWS pitchers who exceeded pitch counts and played professionally, 50% (2/4) required UCLR, while only 1.7% (1/58) of those who did not exceed pitch count recommendations required UCLR ( P = .009). Similarly, among former LLWS pitchers who subsequently played professionally, 23.1% of those who played as a pitcher required UCLR while 0% of those who also played other positions required UCLR ( P = .008). Conclusion: Progression from LLWS pitching to professional baseball is uncommon. Among youth players, both diversification (playing other positions besides pitcher) as well as following current pitch limit regulations may protect against UCLR.
A collaborative approach for semantic time-based video annotation using gamification
Authors: Viana Paula , Pinto José Pedro 
Published: March 2017

AbstractEfficient access to large scale video assets, may it be our life memories in our hard drive or a broadcaster archive which the company is eager to sell, requires content to be conveniently annotated. Manually annotating video content is, however, an intellectually expensive and time-consuming process. In this paper we argue that crowdsourcing, an approach that relies on a remote task force to perform activities that are costly or time-consuming using traditional methods, is a suitable alternative and we describe a solution based on gamification mechanisms for collaboratively collecting timed metadata. Tags introduced by registered players are validated based on a collaborative scoring mechanism that excludes erratic annotations. Voting mechanisms, enabling users to approve or refuse existing tags, provide an extra guarantee on the quality of the annotations. The sense of community is also created as users may watch the crowd’s favourite moments of the video provided by a summarization functionality. The system was tested with a pool of volunteers in order to evaluate the quality of the contributions. The results suggest that crowdsourced annotation can describe objects, persons, places, etc. correctly, as well as be very accurate in time.
A practical person authentication system using second minor finger knuckles for door security
Authors: Kusanagi Daichi , Aoyama Shoichiro , Ito Koichi , Aoki Takafumi 
Published: March 2017

Abstract
This paper proposes a person authentication system using second minor finger knuckles, i.e., metacarpophalangeal (MCP) joints, for door security. This system acquires finger knuckle patterns on MCP joints when a user takes hold of a door handle and recognizes a person using MCP joint patterns. The proposed system can be constructed by attaching a camera onto a door handle to capture MCP joints. Region of interest (ROI) images around each MCP joint can be extracted from only one still image, since all the MCP joints are located on the front face of the camera. Phase-based correspondence matching is used to calculate matching scores between ROIs to take into consideration deformation of ROIs caused by hand pose changes. Through a set of experiments, we demonstrate that the proposed system exhibits the efficient performance of MCP recognition and also show the potential possibilities of second minor finger knuckles for biometric recognition.
Mercaptopurine Ingestion Habits, Red Cell Thioguanine Nucleotide Levels, and Relapse Risk in Children With Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group Study AALL03N1
Authors: Landier Wendy , Hageman Lindsey , Chen Yanjun , Kornegay Nancy , Evans William E. , Bostrom Bruce C. , Casillas Jacqueline , Dickens David S. , Angiolillo Anne L. , Lew Glen , Maloney Kelly W. , Mascarenhas Leo , Ritchey A. Kim , Termuhlen Amanda M. , Carroll William L. , Relling Mary V. , Wong F. Lennie , Bhatia Smita 
Published: March 2017

Purpose Children with acute lymphoblastic leukemia (ALL) are generally instructed to take mercaptopurine (6-MP) in the evening and without food or dairy products. This study examines the association between 6-MP ingestion habits and 6-MP adherence, red cell thioguanine nucleotide (TGN) levels, and risk of relapse in children with TMPT wild-type genotype. Methods Participants included 441 children with ALL receiving oral 6-MP for maintenance. Adherence was monitored over 48,086 patient-days using the Medication Event Monitoring System; nonadherence was defined as adherence rate < 95%. 6-MP ingestion habits examined included: takes 6-MP with versus never with food, takes 6-MP with versus never with dairy, and takes 6-MP in the evening versus morning versus varying times. Results Median age at study was 6 years (range, 2 to 20 years); 43.8% were nonadherent. Certain 6-MP ingestion habits were associated with nonadherence (taking 6-MP with dairy [odds ratio (OR), 1.9; 95% CI, 1.3 to 2.9; P = .003] and at varying times [OR, 3.4; 95% CI, 1.8 to 6.3; P = .0001]). After adjusting for adherence and other prognosticators, there was no association between 6-MP ingestion habits and relapse risk (6-MP with food: hazard ratio [HR], 0.7; 95% CI, 0.3 to 1.9; P = .5; with dairy: HR, 0.3; 95% CI, 0.07 to 1.5; P = .2; taken in evening/night: HR, 1.1; 95% CI, 0.2 to 7.8; P = .9; at varying times: HR, 0.3; 95% CI, 0.04 to 2.7; P = .3). Among adherent patients, there was no association between red cell TGN levels and taking 6-MP with food versus without (206.1 ± 107.1 v 220.6 ± 121.6; P = .5), with dairy versus without (220.1 ± 87.8 v 216.3 ± 121.3; P =.7), or in the evening/night versus morning/midday versus varying times (218.8 ± 119.7 v 195.5 ± 82.3 v 174.8 ± 93.4; P = .6). Conclusion Commonly practiced restrictions surrounding 6-MP ingestion might not influence outcome but may hinder adherence. Future recommendations regarding 6-MP intake during maintenance therapy for childhood ALL should aim to simplify administration.
Health-Related Quality of Life and Survival Outcomes of Pediatric Patients With Nonmetastatic Osteosarcoma Treated in Countries With Different Resources
Authors: Bishop Michael W. , Advani Shailesh M. , Villarroel Milena , Billups Catherine A. , Navid Fariba , Rivera Cecilia , Quintana Juan A. , Gattuso Jami S. , Hinds Pamela S. , Daw Najat C. 
Published: March 2017

Purpose Health-related quality of life (HRQOL) improves throughout treatment of patients with nonmetastatic osteosarcoma. We compared HRQOL for patients in the United States and Chile treated on an international trial (OS99) with polychemotherapy and surgery, and we assessed the relationships among HRQOL measures, event-free survival (EFS), and overall survival (OS). Materials and Methods Patients with newly diagnosed, localized osteosarcoma and their parents completed three HRQOL instruments (PedsQL v.4, PedsQL Cancer v.3, and Symptom Distress Scale [SDS]). Data were collected at four time points throughout therapy. Repeated measures models were used to investigate the effect of treatment site on instrument scores. The log-rank test examined the impact of treatment site on survival outcomes, and Cox proportional hazards regression models evaluated baseline HRQOL measures as predictors of EFS and OS. Results Of 71 eligible patients, 66 (93%) participated in the HRQOL studies in the United States (n = 44) and Chile (n = 22). The median age was 13.4 years (range, 5 to 23 years). Clinical characteristics were similar between treatment sites. US patients reported better scores for physical ( P = .030), emotional ( P = .027), and school functioning ( P < .001). Chilean patients reported poorer scores for worry ( P < .001) and nausea ( P = .007). Patient and parent nausea scores were similar between patients treated in the United States and Chile by the end of therapy. Differences in symptom distress were not observed between the countries. Neither HRQOL measures nor treatment site were associated with EFS or OS. Conclusion Although significant differences in HRQOL were observed between countries, outcomes were similar, and HRQOL measures were not associated with prognosis.
СОЦИАЛЬНО-ЭКОНОМИЧЕСКОЕ РАЗВИТИЕ ТЕРРИТОРИИ НА ОСНОВЕ ГОСУДАРСТВЕННО-ЧАСТНОГО ПАРТНЕРСТВА. ЧАСТЬ 1
Authors: Zakharov Sergey Viktorovich 
Published: March 2017

Раскрыты методические подходы к описанию инструментов государственно-частного партнерства (ГЧП). Проанализированы противоречия, проблемы действенности институциональных средств регулирования эффективности функционирования разных форм ГЧП в российской экономике. Выделены некоторые недостатки законодательной базы как важного институционального инструмента развития ГЧП и регулирования экономических отношений. Обоснована целесообразность расширенного применения корпоративной формы партнерства и коррекции институтов и механизмов правового регулирования взаимовыгодных партнерских отношений, в том числе с участием акционерных обществ. Предложено расширить классификацию форм ГЧП для поиска путей совершенствования правового поля функционирования ГЧП и на этой теоретико-методологической основе внести ряд изменений в соответствующие законодательные акты.Цель: на основе анализа и расширенного толкования сущности и содержания ГЧП расширить классификацию их форм и предложить новые институциональные средства регулирования процессов партнерского взаимодействия государственных структур с предприятиями и социально-экономического развития территории.Метод или методология проведения работы: методология институциональной экономики; методы классификации, анализа экономических отношений и противоречий развития разных форм ГЧП, синтеза решений; проектный и системный, комплексный подход.Результаты: расширена классификация форм ГЧП, а также толкование сущности и содержания партнерских отношений между государством и бизнесом; представлена матричная модель сравнительных характеристик разных форм ГЧП; обоснована необходимость развития институциональных средств регулирования социально-экономического развития территорий с опорой на разные формы ГЧП; разработаны рекомендации по совершенствованию законодательной базы, способствующие повышению эффективности ГЧП и ускорению социально-экономического развития территорий.Область применения результатов: представленные решения и рекомендации предназначены для использования органами законодательной и исполнительной власти для регулирования экономических отношений при активном применении разных форм ГЧП с целью ускорения социально-экономического развития территорий.
Short Communication: Selected medicinal plants in East and North Kalimantan (Indonesia) against Propionibacterium acnes
Authors: ARUNG ENOS TANGKE , PASEDAN WHICLIFFE FIERNALEONARDO , KUSUMA IRAWAN WIJAYA , HENDRA MEDI , SUPRIADI MERY BUDIARTI 
Published: March 2017

Abstract. Arung ET, Pasedan WF, Kusuma IW, Hendra M, Supriadi MB. 2017. Short Communication: Selected medicinal plants in East and North Kalimantan (Indonesia) against Propionibacterium acnes. Biodiversitas 18: 321-325. Based on community based research on ethnomedicine local knowledge and medicinal plant in Indonesia by Medicinal Plant and Traditional Medicine Research and Development Center of Indonesian Ministry of Helath in 2012 and 2015, various data on medicinal plants including for cosmetic in all Indonesia region has been collected. There are 38 medicinal plants use for skin care/cosmetics. This study focused on some selected medicinal plants used by several Dayak ethnic groups in East and North Kalimantan, Indonesia for cosmetic, especially for anti-acne. Four plants were selected for evaluating its property on anti-acne, namely Crotalaria pallida, Lepisanthes amoena, Premna corymbosa, and Vitex pinnata by well diffusion and dilution methods. The zone inhibition (mm) against Propionibacterium acnes of these leaves extract on anti-acne at 1000 mg/mL was 9.33; 16.44; 13.78; 11.00 mm, respectively and chlorampenicol (positive control) was 29.44 mm at 500 mg/mL. These results were in line with traditional used by Dayak tribes in East and North Kalimantan, Indonesia.
Keywords: Anti acne, cosmetic, medicinal plants, traditional medicine
Relationship of soil physical and chemical properties with ecological species groups in Pinus taeda plantation in northern Iran
Authors: ADEL MOHAMMAD NAGHI , DARYAEI MEHRDAD GHODSKHAH , PASHAKI MOHADDESEH SEDIGHI , JALALI JAVAD , KUHESTANI JAVAD SADEGH , JIROUDNEZHAD ROGHAYEH 
Published: March 2017

Abstract. Adel MN, Daryaei MG, Pashaki MS, JalaliJ, KuhestaniJS, Jiroudnezhad R. 2017. Relationship of soil physical and chemical properties with ecological species groups in Pinus taeda plantation in northern Iran. Biodiversitas 18: 422-426. The aim of this study was to investigate the relationship of physical and chemical properties of soils with ecological species groups in Pinus taeda plantation forests in Guilan province, Iran. For this purpose, a random systematic 100 m Ã— 200 m grid sampling plan was used to establish 75 sampling plots. In each plot, soil factors and percent cover of each herbaceous species were recorded. Sub-plots of 32 m2 were used for herbaceous species measurements. At each sampling plot, soil samples were collected in depth of 0-30cm. The result of TWINSPAN analysis revealed five dictinct groups. Multivariate analysis was performed through CANOCO 4.5 to explore the relationship between soil factors and plant community. Results showed that the most important soil factors in these communities were N, P, K, OC, Ca, Mg, TNV, pH, SP, soil texture (clay, sand, silt) and EC. The results indicated that the physical and chemical soil characteristics have a significant role in the growth and distribution of plant communities in the study area.
Keywords: Pinus taeda, plantation, soil properties, vegetation
Effects of habitat degradation and fragmentation on butterfly biodiversity in West Kotawaringin, Central Kalimantan, Indonesia
Authors: HARMONIS HARMONIS , SAUD OSHLIFIN RUCMANA 
Published: March 2017

Harmonis, Saud OR. 2016. Effects of habitat degradation and fragmentation on butterfly biodiversity in West Kotawaringin, Central Kalimantan. Biodiversitasx 18: 500-506. The main purpose of this study was to examine the effects of degradation and fragmentation habitats to butterfly communities. To be specific, species diversity, taxonomy structure, main species in every study sites were observed to find out the effects and correlation of each parameters. Field study was carried out in 8 sites in Kotawaringin Barat, Central Kalimantan Province, Indonesia. The specimens were collected using aerial insect nets and baited traps in January-February 2016. From the result of the study, the total of 1085 individual in 130 species was successfully collected. Based on distribution analysis using Shannon-Wiener index, the diversity of butterfly was in the range of middle to high categories (Hâ€™ = 2.7-3.5). Of another parameter analysis, it showed that butterfly communities were affected by degradation habitat, while fragmentation habitat did not influence to the butterfly communities. Furthermore, the range of degradation level in the study sites did not correlate with the number of species and taxonomy structures, but the distribution of the special-group of main species showed in correlation. Lexias dirtea was only found in dense forests (site S-7), then Neptis hylas and Parantica agleoides appeared in shrub habitat (site S-5 and S-6). The finding indicated that green patches have valuable contribution to conserve the ecosystem as valuable germplasm for butterflies and also arthropods.
Assessing phytoplankton community structure in relation to hydrographic parameters and seasonal variation (Pre & Post Monsoon)
Authors: MIRZAEI M. REZA , SERAJI FERESHTEH , ERFANIFAR ELNAZ , RAD TEYMOUR AMIN , AMINIKHOEI ZAHRA , AZHANG BIZHAN 
Published: March 2017

Mirzaei MR, Seraji F, Erfani E, Rad TA, Aminikhoei Z, Azhang B. 2017. Assessing phytoplankton community structure in relation to hydrographic parameters and seasonal variation (Pre & Post Monsoon). Biodiversitas 18: 507-513. The present study is conducted to assess hydrographical parameters, phytoplankton composition and the relationship between physicochemical parameters and phytoplankton assemblages along Chabahar coastal waters, South coast of Iran. Based on the collected samples from four stations, all the hydrographical parameters such as sea surface temperature, salinity, pH, DO and nitrate, inorganic phosphate, silicate, and phytoplankton assemblages were studied for five months (from April 2014 to August 2014). A total of 165 phytoplankton groups/taxa were observed in which the Dinophyceae formed the dominant group in all seasons. During the pre-monsoon season, Dinophyceae (56.5%) was the most abundant phytoplankton group followed by Bacillariophyceae (40.8%), Cyanophyceae (1.7 %) and Dictyochophyceae (0.8%). Meanwhile, in the post-monsoon season, Dinophyceae was dominant (49.5%), followed by Bacillariophyceae (46.7%), Cyanophyceae (1.8%), and Dictyochophyceae (1.8%). The highest phytoplankton density was in mid-May (19584953Â± 345182 cell per litter) and the lowest was in late July (163928Â± 1790 cells per liter). Salinity, nitrate, phosphate, silicate showed significant variation (p<0.05) among seasons while pH, seawater temperature, dissolve oxygen did not show significant differences in all stations over the study periods (p<0.05). Phytoplankton density correlated positively with water temperature and salinity. Results showed an increased concentration in phytoplankton density during Pre-monsoon season followed by Post-monsoon and monsoon season.