bluuebunny/crossref_metadata_2025_split huggingface dataset:
WHAT IS RESPONSIBILITY TOWARD THE PAST? ETHICAL, EXISTENTIAL, AND TRANSGENERATIONAL DIMENSIONS
Authors: Elgabsi Natan 
Published: September 2024

ABSTRACTToday, there is a growing interest in the ethics of the human and social sciences, and in the discussions surrounding these topics, notions such as responsibility toward the past are often invoked. But those engaged in these discussions seldom acknowledge that there are at least two distinct logics of responsibility underlying many debates. These logics permeate a Western scholarly tradition but are seldom explicitly discussed. The two logics follow the Latin and Hebrew concepts of responsibility: spondeo and acharayut. The purpose of this article is to make an ethical argument: to explain, based on the work of Emmanuel Levinas and others, what kind of ethical‐existential logic of responsibility acharayut is and how it differs from and challenges other concepts of responsibility in moral philosophy and the human sciences. I am especially concerned with what this logic implies with regard to reading and writing about the past. Responsibility is not necessarily congruent with performing a scientific (historical) task or defending the (political, juridical) interests of a group of people. Instead, a “guiltless responsibility” to people of other generations points to something that I refer to as a transgenerational responsibility. I contrast this transgenerational responsibility to inherited guilt and related ideas of generational interconnectedness, which follow the logic of spondeo. Inherited guilt suggests that a responsible relation the past is to either identify with or blame a group of people in the past. Contrary to inherited guilt, a commitment to acharayut means constantly probing one's responsibility to people of the past (for their posterity) and people of the future (as their predecessors) precisely because people of the present are not people of the past or people of the future.
Rapid selection for increased dispersal rates by the endangered butterfly Phengaris (Maculinea) arion across restored landscapes
Authors: Simcox David J. , Meredith Sarah A. , Thomas Jeremy A. 
Published: September 2024

Abstract
When designing restorations for durable metapopulations of endangered butterflies, it is important to understand how frequently the adults mix between sites and their probability of colonising vacant patches unassisted by human translocations.
We analysed 43 examples of natural dispersal by Phengaris arion L. to restored sites in three regions following its reintroduction after extinction to the UK. We compared the years taken to reach restored habitats with the distance from a source colony, the number and density of P. arion on source sites, the size of source sites, the nature of the intervening matrix, summer temperatures, the incidence of drought and whether a more dispersive phenotype has evolved across restored landscapes.
Isolation of sites was the most important constraint on the colonisation of new habitats, followed by the number, but not the density, of P. arion on source sites. Emigration was more frequent in warm summers and when the habitat was degraded by drought, but neither factor remained significant in multifactorial analyses. A matrix of woodland between sites was a greater barrier to dispersal than open or mixed terrain, but again insignificant in multifactorial analyses.
A more mobile phenotype of P. arion has evolved while it exploited vacant habitat patches during its first 10–12 generations in the UK. Adults now fly twice as far to find new colonies as in the early years. We map the probabilities of linking restored sites with neighbouring populations in three former landscapes in the Cotswold Hills of Gloucestershire, UK.
Patient safety in the pandemic: Experiences of charge nurses
Authors: Ünal Aysun , Öncü Yasemin Ayhan , Arikan Emine 
Published: September 2024

AbstractAimThe aim of this study was to identify charge nurses' experiences ensuring patient safety during the coronavirus disease 2019 (COVID‐19) pandemic.MethodsThe research was conducted with charge nurses between July 2021 and February 2022. Research data were collected using a semi‐structured interview with two main questions, six sub‐questions and an audio recording. Interviews were conducted with 12 charge nurses and lasted ≈30 min. The content analysis method was used to transfer the collected data to written documents and define them to analyse the individual interview data. Content analyses were conducted independently by three different researchers. Inclusion and exclusion criteria for content were established to ensure consistency among all researchers. Researchers independently developed a coding scheme for content analysis based on the research objectives and applied it to the content. Intercoder reliability was assessed with Cohen's kappa coefficient to measure the consistency of coding among researchers.ResultsThree main themes were identified as a result of the content analysis. The themes identified after independent examination by the three researchers were ‘ensuring safety and protection’, ‘sustaining motivation and resilience’ and ‘organizational restructuring and challenges’.ConclusionsThis study highlights the challenges faced by charge nurses during the COVID‐19 pandemic and their critical role in maintaining patient safety. The findings emphasize the importance of organizational adaptability, continuous motivation and comprehensive risk management strategies. Charge nurses played a key role in enhancing safety measures and fostering a culture of resilience among healthcare staff. Moving forward, these insights should guide health policies and practices to better prepare for future public health crises, ensuring the safety of both patients and staff.
Systematic review and meta‐analysis of diagnostic test accuracy in chronic wound's microbiology
Authors: Berenguer‐Pérez Miriam , Manzanaro‐García Nerea , González‐de la Torre Héctor , Durán‐Sáenz Iván , Hernández Martínez‐Esparza Elvira , Diaz Herrera Miguel Ángel , González Suárez Borja , Verdú‐Soriano José 
Published: September 2024

AbstractPurposeThis study aims to assess the diagnostic accuracy of non‐culture‐based methodologies for detecting microorganisms in chronic wounds.MethodsWe systematically reviewed studies that evaluated the diagnostic accuracy of alternative tests in chronic wound samples, excluding studies focused on animal samples or unrelated conditions. The search encompassed PubMed, CINAHL, Scopus and Web of Science databases, employing the QUADAS‐2 tool for risk of bias assessment. Our search included the PubMed, CINAHL, Scopus and Web of Science databases, and we assessed the risk of bias using the QUADAS‐2 tool. A meta‐analysis was conducted on polymerase chain reaction (PCR) and colorimetric methods to determine sensitivity, specificity, diagnostic odds ratio, and summary receiver‐operating characteristic (sROC) curves using a random‐effects model. For methods not suitable for quantitative synthesis, a narrative synthesis was performed.ResultsNineteen studies involving various types of chronic wounds were analysed, revealing diverse diagnostic methods including fluorescence, PCR, colorimetry, voltammetry, electronic nose, biosensors, enzymatic methods, staining and microscopy. Combining fluorescence with clinical signs and symptoms (CSS) versus culture showed significant accuracy. Colorimetry demonstrated low sensitivity but high specificity, with a diagnostic odds ratio of 6.3. PCR generally exhibited good accuracy, although significant heterogeneity was noted, even in subgroup analyses.ConclusionsThis study identified a broad spectrum of diagnostic approaches, highlighting the superior diagnostic accuracy achieved when microbiological analysis is combined with clinical assessments. However, the heterogeneity and methodological variations across studies present challenges in meta‐analysis. Future research should aim for standardized and homogeneous study designs to enhance the assessment of diagnostic accuracy for alternative methods.
Effectiveness of integrated care models for stroke patients: A systematic review and meta‐analysis
Authors: Liu Beixue , Cai Jingyi , Zhou Lanshu 
Published: September 2024

AbstractIntroductionGiven that stroke is a leading cause of disability and mortality worldwide, there is an urgent need for a coordinated healthcare approach to mitigate its effects. The objectives of this study were to perform a systematic review and meta‐analysis of stroke integrated care models and develop recommendations for a representative model.DesignA systematic review and meta‐analysis.MethodsThe literature search identified randomized controlled trials comparing integrated care models with standard care for stroke patients. The included studies followed PICOs inclusion criteria. The qualitative analysis included creating a flowchart for the literature screening process, and tables detailing the basic characteristics of the included studies, the adherence to the ten principles and the results of the quality assessments. Subsequently, quantitative meta‐analytical procedures were conducted to statistically pool the data and quantify the effects of the integrated care models on stroke patients' health‐related quality of life, activities of daily living, and depression. The China National Knowledge Infrastructure (CNKI), Wanfang Data, Chongqing VIP Chinese Science and Technology Periodical Database (VIP), China Biology Medicine Disc (CBMDISC), Cochrane Library, Cumulated Index to Nursing and Allied Health Literature (CINAHL), PubMed, Web of Science, Embase, Google Scholar, and Clinical Trials were searched from inception to March 13, 2024.ResultsOf the 2547 obtained articles, 19 were systematically reviewed and 15 were included in the meta‐analysis. The integrated care models enhanced stroke patients' health‐related quality of life, ability to perform activities of daily living, and reduced depression. Adherence to the 10 principles varied: comprehensive services, patient focus, and standardized care delivery had strong implementation, while gaps were noted in geographic coverage, information systems, governance structures, and financial management.ConclusionIntegrated care models improve outcomes for stroke patients and adherence to the 10 principles is vital for their implementation success. This study's findings call for a more standardized approach to implementing integrated care models, emphasizing the need for integrated services, patient‐centred care, and interdisciplinary collaboration, while also addressing the identified gaps in terms of integration efforts.Clinical RelevanceThis study provides evidence‐based recommendations on the most effective integrated care approaches for stroke patients, potentially leading to better patient outcomes, reduced healthcare costs, and improved quality of life.
The Effect of Monobenzone Cream on Oxidative Stress and Its Relationship With Serum Levels of IL‐1β and IL‐18 in Vitiligo Patients
Authors: Khalid‐Meften Ahmed , Liaghat Mahsa , Yazdanpour Mohammad , Nabi‐Afjadi Mohsen , Hosseini Asieh , Bahreini Elham 
Published: September 2024

ABSTRACTBackgroundMonobenzyl ether hydroquinone (MEBHQ) is a cream that promotes the spread and evenness of skin patches in vitiligo. Our aim was to investigate the oxidative and inflammatory effects of this cream on vitiligo patients consuming MEBHQ.MethodsA case–control study was conducted with three groups of 30 people from the control group, vitiligo patients before and after treatment. The percentage of vitiligo spots was determined by a specialist doctor. The levels of biochemical factors, oxidative stress profile and inflammatory factors were measured by enzymatic, colorimetric and ELISA methods, respectively.ResultsVitiligo patients showed a high level of inflammation and oxidative stress compared to healthy people. Although after 3 months of using MBEHQ cream, the percentage of skin spots in vitiligo patients increased from an average of 63%–91% and the skin color became almost uniform, but it still increased the level of oxidative stress and inflammation in these patients. Although the level of oxidative stress increased significantly in these patients, there was no significant increase in the level of malondialdehyde. The lack of significant differences in the levels of biochemical factors between healthy people and vitiligo patients before and after using the treatment shows the absence of side effects.ConclusionThe use of MBEHQ increased the size of skin spots and uneven skin color in vitiligo patients. Although MBEHQ did not show side effects such as diabetes, liver and kidney diseases, it increased the levels of oxidative stress and inflammatory cytokines, which needs further study.
A Randomized, Participant‐ and Evaluator‐Blinded, Matched‐Pair, Prospective Study Comparing the Safety and Efficacy Between Polycaprolactone and Polynucleotide Fillers in the Correction of Crow's Feet
Authors: Choi Sun Young , Koh Young Gue , Yoo Kwang Ho , Han Hye Sung , Seok Joon , Kim Beom Joon 
Published: September 2024

ABSTRACTBackgroundDermal fillers have gained widespread popularity for facial cosmetic enhancement and anti‐aging treatments. Recently, polycaprolactone (PCL) and polynucleotides (PN) fillers have emerged as promising options owing to their safety and long‐lasting effects.ObjectivesThis study aimed to compare the efficacy and safety of a novel PCL‐based dermal filler (DLMR01) with purified PN filler (RJR: Rejuran) in correcting crow's feet wrinkles.Materials and MethodsA randomized, evaluator‐blinded, prospective split‐face study was conducted with 218 healthy Asian participants. The primary outcome was in the improvement rate of the Crow's Feet Grading Scale (CFGS) at rest after 12 weeks. Secondary outcomes included the improvement rate of the CFGS at expression and rest at earlier time points, changes in CFGS, and the Global Aesthetic Improvement Scale (GAIS) assessment.ResultsThe results showed that DLMR01 was not inferior to RJR in improving crow's feet wrinkles, with a significantly higher CGFS improvement rate at week 12. Both fillers demonstrated good safety profiles, with mild and tolerable adverse events. No serious adverse events were reported during the study period.ConclusionDLMR01, a PCL‐based dermal filler, showed effectiveness and safety in improving wrinkles described as crow's feet. The study suggests that DLMR01 could be a promising option for noninvasive anti‐aging treatments.
Assessing Skin Tear Knowledge Among Nurses: A Multicentre Cross‐Sectional Survey
Authors: Wang Guandong , Wang Haibo , Wang Liang , Li Wenjuan , Xu Danyang , Chen Jinhao 
Published: September 2024

ABSTRACTAimsTo assess the knowledge of nurses in Chinese hospitals regarding skin tears, focusing on evaluating their understanding and proficiency in managing and preventing skin tears, exploring the impact of demographic and professional factors on their knowledge levels and identifying specific areas where additional training or education is needed.DesignThis study is a multicentre cross‐sectional survey conducted in the Henan province of China using a stratified cluster sampling method.MethodsThe study utilised the Chinese version of the Skin Tear Knowledge Assessment Instrument (OASES) for evaluating nurses' knowledge levels based on a questionnaire comprising 22 questions on the online platform Wenjuanxing (www.wjx.cn). All questions had to be answered, with only one option selectable per question. Response validity was ensured by excluding questionnaires that showed a clear response pattern, were completed in under 60 s, or scored 0 points. Descriptive analysis, item‐level analysis and multiple linear regression analysis were performed.ResultsA total of 1675 clinical nurses participated in this study. Age was a significant factor influencing skin tear knowledge, with older nurses (age, 41–60 vs. 18–40 years) demonstrating higher knowledge scores. Additionally, female nurses exhibited higher average knowledge scores compared to male nurses. Further, different departments, education levels, job titles and having completed relevant courses significantly influenced skin tear knowledge among nurses. However, on multivariate analyses, we found that working in the intensive care unit, having a higher education background and job title and having studied courses on wound, ostomy or incontinence were independent factors influencing knowledge on skin tear, indicating the need for targeted educational interventions.ConclusionIn conclusion, targeted educational interventions and continuous professional development are essential to bridge the identified knowledge gaps among nurses in Chinese hospitals regarding skin tear management.Reporting MethodThe Strengthening the Report of Observational Studies in Epidemiology checklist guidelines were followed.Implications for the Profession and/or Patient CareEnhancing nurses' knowledge and skills in skin tear management through targeted educational programmes could improve patient care quality, reduce the incidence of skin tears and promote better wound care outcomes in clinical settings.ImpactThis study addresses the problem of knowledge gaps in skin tear management among nurses. The main findings indicate varied understanding and significant factors influencing this knowledge. The research impacts nurses and patients in Chinese hospitals, emphasising the need for specialised training and professional development to improve skin tear management and patient care. No patient or public contribution.
Association between diabetes mellitus and miscarriage, recurrent miscarriage: A meta‐study
Authors: Miao Suying , Yang Liwei 
Published: September 2024

AbstractBackgroundPrevious studies provided inconsistent associations between diabetes mellitus (DM) and miscarriage, recurrent miscarriage (RM). Therefore, this study aims to evaluate the association between DM and miscarriage, specifically RM, through a meta‐analysis approach.MethodsWe searched for articles published before July 2023 in PubMed and Web of Science databases. STATA 12.0 software was used to compute all the results collected from included studies.ResultsDM was associated with a higher risk of miscarriage, RM (miscarriage: odds ratio [OR]/relative risk [RR] = 1.23, 95% confidence interval [CI] 1.13 to 1.34; RM: OR/RR = 1.73, 95% CI 1.55 to 1.94). T1DM was associated with a higher risk of miscarriage (OR/RR = 1.16, 95% CI 1.07 to 1.26). Similarly, T2DM showed a higher risk of miscarriage (OR/RR = 1.44, 95% CI 1.23 to 1.68). Miscarriage, RM were associated with a higher risk of DM (miscarriage: OR/RR = 1.14, 95% CI 1.08 to 1.19; RM: OR/RR = 1.14, 95% CI 1.08 to 1.20). Furthermore, miscarriage was found to be associated with a higher risk of T2DM (OR/RR = 1.08, 95% CI 1.05 to 1.11).ConclusionIn conclusion, our meta‐analysis findings indicate a significant association between DM and miscarriages as well as RM. As a result, women with a history of miscarriage should consider regular monitoring of their metabolic health as a potential benefit. Nevertheless, it is important to note that further research is needed to validate the results of our study and shed light on the biological mechanisms underlying these associations.
Fe, Zn, and Mg stable isotope systematics of acapulcoite lodranite clan meteorites
Authors: Chernonozhkin Stepan M. , Pittarello Lidia , Hublet Genevieve , Claeys Philippe , Debaille Vinciane , Vanhaecke Frank , Goderis Steven 
Published: September 2024

AbstractThe processes of planetary accretion and differentiation, whereby an unsorted mass of primitive solar system material evolves into a body composed of a silicate mantle and metallic core, remain poorly understood. Mass‐dependent variations of the isotope ratios of non‐traditional stable isotope systems in meteorites are known to record events in the nebula and planetary evolution processes. Partial melting and melt separation, evaporation and condensation, diffusion, and thermal equilibration between minerals at the parent body (PB) scale can be recorded in the isotopic signatures of meteorites. In this context, the acapulcoite–lodranite meteorite clan (ALC), which represents the products of thermal metamorphism and low‐degree partial melting of a primitive asteroid, is an attractive target to study the processes of early planetary differentiation. Here, we present a comprehensive data set of mass‐dependent Fe, Zn, and Mg isotope ratio variations in bulk ALC species, their separated silicate and metal phases, and in handpicked mineral fractions. These non‐traditional stable isotope ratios are governed by mass‐dependent isotope fractionation and provide a state‐of‐the‐art perspective on the evolution of the ALC PB, which is complementary to interpretations based on the petrology, trace element composition, and isotope geochemistry of the ALC. None of the isotopic signatures of ALC species show convincing co‐variation with the oxygen isotope ratios, which are considered to record nebular processes occurring prior to the PB formation. Iron isotopic compositions of ALC metal and silicate phases broadly fall on the isotherms within the temperature ranges predicted by pyroxene thermometry. The isotope ratios of Mg in ALC meteorites and their silicate minerals are within the range of chondritic meteorites, with only accessory spinel group minerals having significantly different compositions. Overall, the Mg and Fe isotopic signatures of the ALC species analyzed are in line with their formation as products of high‐degree thermal metamorphism and low‐degree partial melting of primitive precursors. The δ66/64Zn values of the ALC meteorites demonstrate a range of ~3.5‰ and the Zn is overall isotopically heavier than in chondrites. The superchondritic Zn isotopic signatures have possibly resulted from evaporative Zn losses, as observed for other meteorite parent bodies. This is unlikely to be the result of PB differentiation processes, as the Zn isotope ratio data show no covariation with the proxies of partial melting, such as the mass fractions of the platinum group and rare earth elements.
Central venoplasty followed by ‘double guidewire railroad technique’ as a bailout strategy in difficult tunnelled dialysis catheter insertion
Authors: Sulaiman Shabna , Razik Abdul 
Published: September 2024

AbstractEnd‐stage renal disease (ESRD) patients frequently encounter challenges at the time of dialysis catheter insertion from concomitantly associated with thoracic central venous obstruction (TCVO). TCVO complicates the placement of tunnelled dialysis catheters (TDCs). In cases where TCVO is unexpectedly encountered and TDC insertion becomes difficult, central venoplasty followed by catheter reinsertion is required. This report details a novel technique to salvage a TDC that was trapped at the TCVO site after removal of the peel‐away sheath. We describe the case of a 67‐year‐old diabetic male ESRD patient on haemodialysis since 2017, with history of multiple prior accesses, who presented with acute thrombosis of his arteriovenous fistula. TDC placement was attempted via the left internal jugular vein (IJV). Angiography revealed severe stenosis at the left brachiocephalic vein‐superior vena cava confluence, necessitating venoplasty. Post‐venoplasty, the TDC could not be advanced past the IJV venous entry site due to unfavourable catheter tip profile. Utilising a double guidewire railroad technique, the TDC was successfully reinserted, ensuring functional dialysis. The technique carries potential risks, which mandates careful hemodynamic monitoring and prophylactic measures. In conclusion, percutaneous placement of a TDC following a central venoplasty is at times life‐saving in patients with exhausted peripheral vascular access and concomitant TCVO. In the absence of a peel‐away sheath, TDC reinsertion using a double guidewire railroad technique is a helpful technique for salvaging the catheter, especially in financially‐constrained settings.