bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ALMA Legacy Survey of Class 0/I Disks in Corona australis, Aquila, chaMaeleon, oPhiuchus north, Ophiuchus, Serpens (CAMPOS). I. Evolution of Protostellar Disk Radii
Authors: Hsieh 謝 Cheng-Han 承翰 , Arce Héctor G. , Maureira María José , Pineda Jaime E. , Segura-Cox Dominique , Mardones Diego , Dunham Michael M. , Arun Aiswarya 
Published: September 2024

Abstract
We surveyed nearly all the embedded protostars in seven nearby clouds (Corona Australis, Aquila, Chamaeleon I and II, Ophiuchus North, Ophiuchus, Serpens) with the Atacama Large Millimeter/submillimeter Array at 1.3 mm observations with a resolution of 0.″1. This survey detected 184 protostellar disks, 90 of which were observed at a resolution of 14–18 au, making it one of the most comprehensive high-resolution disk samples across various protostellar evolutionary stages to date. Our key findings include the detection of new annular substructures in two Class I and two flat-spectrum sources, while 21 embedded protostars exhibit distinct asymmetries or substructures in their disks. We find that protostellar disks have a substantially large variability in their radii across all evolutionary classes. In particular, the fraction of large disks with sizes above 60 au decreases as the protostar evolves from Class 0 to Class I. Compiling the literature data, we discovered an increasing trend of the gas disk radii to dust disk radii ratio (R
gas,Kep/R
mm) with increasing bolometric temperature (T
bol). Our results indicate that the dust and gas disk radii decouple during the early Class I stage. However, in the Class 0 stage, the dust and gas disk sizes are similar, which allows for a direct comparison between models and observational data at the earliest stages of protostellar evolution. We show that the distribution of radii in the 52 Class 0 disks in our sample is in high tension with various disk formation models, indicating that protostellar disk formation remains an unsolved question.
The JWST-SUSPENSE Ultradeep Spectroscopic Program: Survey Overview and Star Formation Histories of Quiescent Galaxies at 1 < z < 3
Authors: Slob Martje , Kriek Mariska , Beverage Aliza G. , Suess Katherine A. , Barro Guillermo , Bezanson Rachel , Brammer Gabriel , Cheng Chloe M. , Conroy Charlie , de Graaff Anna , Förster Schreiber Natascha M. , Franx Marijn , Lorenz Brian , Mancera Piña Pavel E. , Marchesini Danilo , Muzzin Adam , Newman Andrew B. , Price Sedona H. , Shapley Alice E. , Stefanon Mauro , van Dokkum Pieter , Weisz Daniel R. 
Published: September 2024

Abstract
We present an overview and first results from the Spectroscopic Ultradeep Survey Probing Extragalactic Near-infrared Stellar Emission (SUSPENSE), executed with NIRSpec on JWST. The primary goal of the SUSPENSE program is to characterize the stellar, chemical, and kinematic properties of massive quiescent galaxies at cosmic noon. In a single deep NIRSpec/MSA configuration, we target 20 distant quiescent galaxy candidates (z = 1–3, H
AB ≤ 23), as well as 53 star-forming galaxies at z = 1–4. With 16 hr of integration and the G140M-F100LP dispersion-filter combination, we observe numerous Balmer and metal absorption lines for all quiescent candidates. We derive stellar masses (logM
*/M
⊙ ∼ 10.2–11.5) and detailed star formation histories (SFHs) and show that all 20 candidate quiescent galaxies indeed have quenched stellar populations. These galaxies show a variety of mass-weighted ages (0.8–3.3 Gyr) and star formation timescales (∼0.5–4 Gyr), and four out of 20 galaxies were already quiescent by z = 3. On average, the z > 1.75 [z < 1.75] galaxies formed 50% of their stellar mass before z = 4 [z = 3]. Furthermore, the typical SFHs of the galaxies in these two redshift bins (z
mean = 2.2 [1.3]) indicate that galaxies at higher redshift formed earlier and over shorter star formation timescales compared to lower redshifts. Although this evolution is naturally explained by the growth of the quiescent galaxy population over cosmic time, number density calculations imply that mergers and/or late-time star formation also contribute to the evolution. In future work, we will further unravel the early formation, quenching, and late-time evolution of these galaxies by extending this work with studies on their chemical abundances, resolved stellar populations, and kinematics.
La prise en compte de l’environnement dans le budget et les comptes de l’État selon la Cour des comptes
Authors: Boullanger Hervé , Degron Robin 
Published: September 2024

In 2023, the French Cour des Comptes published several reports on the State’s green public finances. Taking a strong stance on a subject of great importance for the effective implementation of the ecological transition, the High Court has taken a step back from the Finance Acts for 2020 to 2023 in order to take stock of the famous “green budget”.	Placing the French approach in an international perspective, the Court underlines the value of this pioneering initiative. However, it points to the many limitations of a project with a limited scope, which for the moment remains focused on the central government alone. It calls for an improvement in extra-financial reporting within the public sector and its many public establishments.
Psychiatric nurses’ experiences implementing a model for constructive group therapy in mood disorders
Authors: Visagie Hester M.P. , Temane Annie , Poggenpoel Marie 
Published: September 2024

Background: In South Africa, various treatment modalities from abroad have been implemented to treat patients with mood disorders. This article is based on a South African model that has been developed, implemented and evaluated for psychiatric nurses to use in facilitating constructive group therapy for patients with mood disorders.Objectives: This study aimed to describe psychiatric nurses’ experiences in implementation of a model to facilitate constructive group therapy for patients with mood disorders.Method: A qualitative, exploratory, descriptive and contextual research design was used for this study. Participants were psychiatric nurses working in an inpatient unit for patients with mood disorders in a public psychiatric hospital.Results: The study revealed that psychiatric nurses experienced the model as a supportive tool to facilitate constructive interaction among patients with mood disorders. The model was beneficial in creating a safe space for patients to share and deal with their challenges, promoting optimal functioning outside the hospital setting. The model’s implementation also fostered improvement in psychiatric nurses’ personal and professional skills.Conclusion: The model emphasised psychiatric nurses’ importance in treating patients with mood disorders and ensuring positive patient experiences and outcomes.Contribution: This study contributes to the theory of clinical psychiatric nursing practice and the empowerment of psychiatric nurses, creating self-awareness related to working with patients with mood disorders.
African theology of reconstruction and queer epistemic violence: A theo-ethical discourse
Authors: Mdokwana Ayanda 
Published: September 2024

The legacies of colonialism in South Africa and broadly in Africa have problematised discourses on violence and discrimination. To counter coloniality and its continued efforts to dehumanise Africa, many Africans have often uncritically embraced certain notions of African culture that exacerbates the problem of homophobic violence and discrimination. This has left certain African discourses embracing ubuntu without critically addressing the violence and discrimination where ubuntu is often promoted. Recognising the attempts of African reconstruction theologians such as Mugambi and Ka Mana who advocate the necessity for African epistemic paradigms or epistemic justice, I engage their paradigms considering epistemic violence from the context of the queer community. Ubuntu must be understood within the context of African holism, a framework which African reconstruction theology makes use of. Using Dotson’s three orders of epistemic oppression, I argue that Mugambi’s theological paradigm could become problematic for the queer community because of the epistemic shells it carries into the future from the past. Considering the queer community, I argue that the epistemic flexibility of Ka Mana’s theology of reconstruction allows for more engagement because of its commitment to an ethic of African holism. At the heart of such an ethic is a commitment to the unity and the interconnectedness between God, humans, ancestors, plants and animals. This paper makes a theological contribution by engaging queer epistemic violence from the context of two African theological reconstruction paradigms.Intradisciplinary and/or interdisciplinary implications: This paper engages discourses from African masculinities, social sciences, African theology and philosophy with reference to epistemic violence enacted against the queer community.
Coleus forskohlii shows anti-psoriatic activity in imiquimod-induced psoriasis rats
Authors: Majhi Sagarika , Chauhan Iti , Kumar Deepak , Alam Md. Niyaz , Hussain Md. Sarfaraj , Iqbal Muzaffar 
Published: September 2024

Objective:
To evaluate anti-psoriatic activity of Coleus forskohlii in rats with imiquimod-induced psoriasis.

Methods:
Imiquimod was used to induce psoriasis in rats. Body weight, skin thickness, erythema, scaling, spleen weight, and histological alternations were measured to assess the effect of Coleus forskohlii. Furthermore, an emulgel formulation containing Coleus forskohlii 10% was prepared and characterized along with its ex vivo permeation studies.

Results:
The emulgel formulation containing Coleus forskohlii 10% had a pH of 5.40±0.36, with optimum spreadability of (31.67±2.08) g/(cms) and viscosity of (15 966.67±1 274.10) cps, and enhanced both the rate and the extent of drug permeation through psoriatic skin. In an ex vivo study, the quantity of drug permeated (19.18%), deposited (52.38%), and drug remaining in the donor compartments (28.31%) was satisfactory. Coleus forskohlii significantly alleviated imiquimod-induced psoriasis by increasing glutathione and superoxide dismutase activity, decreasing malondialdehyde and nitric oxide levels, and alleviating histological alternations in rat skin.

Conclusions:

Coleus forskohlii can alleviate imiquimod-induced psoriasis, which may be used as a therapeutic candidate for the treatment of psoriasis.
Unmasking Ataxic Guillain–Barre Syndrome: A Rare Presentation
Authors: Ravikumar Yeliyur Sreerangachar , Prasad Mayagondanahally Chandrashekaraiah , Shetty Nikita , Mahadeviah Mahesh , Thippeswamy Thippeswamy , Roberts Bernice , Wajpey Radha 
Published: September 2024

Abstract
A 68-year-old right-handed male with a history of hypertension presented with unsteadiness while walking for 5 days preceded by a vague pain in the left shoulder and both thighs and paresthesias in all extremities. It rapidly progressed to severe gait ataxia, bilateral facial palsy, and speech difficulties. On examination, he had bilateral lower motor neuron type of facial palsy, a wide-based stance, gait ataxia, left-sided hypotonia, cerebellar signs, and generalized areflexia. He had left-sided hypotonia and normal power of all four limbs. Sensory system examination was normal, and Rhomberg’s sign was negative. He had no ophthalmoplegia. While initial considerations pointed toward a cerebrovascular accident, normal magnetic resonance imaging results prompted us to do a lumbar puncture and cerebrospinal fluid analysis, which revealed albuminocytological dissociation indicative of Guillain–Barré Syndrome (GBS). Nerve conduction studies then confirmed our diagnosis. Given these results and a preceding respiratory infection, the patient was diagnosed with a rare ataxic variant of GBS. The patient was treated with plasmapheresis following which he showed dramatic clinical improvement. He was subsequently able to walk without support and perform the majority of his day-to-day activities on his own. He was discharged in a hemodynamically stable condition. This case report, thus, highlights a rare ataxic variant of GBS presenting with acute onset ataxia, areflexia, and facial diplegia. Thus, understanding the GBS and its variants is crucial to managing rare presentations swiftly and avoiding severe complications. It has tremendous scope for further research to understand the pathophysiological dynamics completely and find more targeted therapeutic approaches. We, thus, present a rare case of an ataxic variant of GBS with acute onset ataxia, areflexia, and facial diplegia.
Anesthesia Management of a Patient Having Allgrove Syndrome
Authors: Shah Rutvi , Rajadurai Sivanesan , Yadav Shilpi , Har Archana 
Published: September 2024

Abstract

Background:
Allgrove syndrome is an autosomal recessive disorder characterized by achalasia cardia, alacrimia and adrenocorticotropic hormone resistant adrenal insufficiency with progressive neurological impairment with or without mental retardation.

Materials and Methods:
Patient had undergone Heller’s myomectomy under GA. PAC was done, all routine investigations, oesophageal motility tests, ACTH level, Schirmer test was done. She was pre-medicated with glycopyrrolate, midazolam and induced with fentanyl, propofol, vecuronium, intubated with cuffed ET tube 6.5 and reversed with Neostigmine and glycopyrrolate.

Result and Conclusion:
Careful pre-operative evaluation, choice of sedatives, induction agents, muscle relaxant to avoid hyperventilation, hypokalemia, close monitoring of ABG and electrolytes, careful glycaemic control, eye protection, care to avoid aspiration and regurgitation are imperative for optimal management with Allgrove syndrome. The co-ordination of care for these patients require a multidisciplinary team of endocrinologist, neurologist, gasteroenterologist, ophthalmologist, surgeons and anaesthesiologists.
We successfully conducted this case of 22 yrs old female with ALLGROVE SYNDROME.
Study Protocol for a Prospective Observational Analytical Multicentric Study Evaluating the Efficacy of Pistacia lentiscus Plant (Rumi Mastagi) in Patients With Diabetic Gastroparesis Using the Gastroparesis Cardinal Symptom Index
Authors: Mittal Rashi , Raina Rohit , Routhu Balachandra , Bairwa Mukesh , Rastogi Deepak , Bhatt Neelambar , Lohani Kailash Chandra , Tiwari Mohan , Joshi Manoj , Joshi Chandra Shekhar , Pant Dinesh C. , Bhatnagar Jag Mohan , Shah Sanjay , Bhardwaj Ram , Gupta Sanjay , Verma Amit , Shrivastava Narendra Bahadur , Aggarwal Pradeep Kumar , Kant Ravi 
Published: September 2024

Abstract

Introduction:
Diabetes is a group of metabolic diseases characterized by hyperglycemia due to insulin secretion or action defects. Gastrointestinal neuropathies in patients with diabetes represent vital aspects of the chronic course of the disease. This can be perceived as chronic delayed gastric emptying associated with nausea, vomiting, postprandial fullness, weight loss, anorexia, and abdominal pain without evidence of mechanical obstruction. Traditional treatments for diabetic gastroparesis include dietary changes and medication, but severe cases may require surgery or gastric electrical stimulation. Pistacia species extracts suggest alleviating gastrointestinal symptoms, yet no Indian studies support the evidence despite Pistachia plant species being present in the Great Himalayan regions. This study explores the therapeutic potential of Pistacia plants in treating diabetic gastroparesis, leveraging their natural antioxidants to enhance gut motility.

Materials and Methods:
This randomized controlled trial will be conducted in two regions of Uttarakhand, India: Garhwal (7 centers) and Kumaon (8 centers) over a total of 15 centers. Each center will enroll 10 patients with diabetic gastroparesis who consent to participate based on a predefined Gastroparesis Cardinal Symptom Index (GCSI) score, totaling 150 patients using convenience sampling. Patients with GCSI scores ≥15 will receive twice-daily drug therapy for 10 days, overseen by a designated study observer at each center. Data will be collated at AIIMS Rishikesh for analysis.

Discussion:
This study aims to validate the effectiveness of Pistacia lentiscus plant extract in treating diabetic gastroparesis, addressing a critical gap in Indian literature. If successful, P. lentiscus could offer a cost-effective and minimally invasive intervention for severe gastroparesis in India.

Conclusion:
The study’s robust design and methodology inspire confidence in its potential contribution to diabetes management.
Benign Granular Cell Tumor of the Breast: A Clinical and Imaging Dilemma
Authors: Olarinoye-Akorede Sefiya Adebanke , Farouk Bilkisu 
Published: September 2024

Abstract
Granular cell tumor (GCT) is mostly a benign tumor of Schwann cells that can affect many organs, especially in the head and neck, but on rare occasions, it is seen in the breast. The inability to distinguish it clinically and radiologically from malignancy as well as its unusual appearance in the sonography, as in this case, pose a diagnostic challenge. Nonetheless, the diagnosis still needs to be made because the management of the GCT differs from that for malignancy. In this case report, we present the clinical, ultrasound features, and histologic findings of a breast mass in a 38-year old woman, which was preoperatively thought to be breast cancer until proven benign on histologic analysis. This case report highlights the importance of making the distinction, especially in a resource-poor setting, to avoid unrequired expensive treatment.
Comparison of Pediatric Risk of Mortality (PRISM III) score with Pediatric Index of Mortality (PIM III) score in Pediatric Intensive Care Unit: A Single center, prospective observational study from South India
Authors: Srinivas Nidhi , Venugopal Kavya , Venkatesha Gurudutta Avathi , Chidanand Nagalatha 
Published: September 2024

Abstract

Background:
Pediatric risk of mortality (PRISM III) score and pediatric index of mortality (PIM III) scores are most recent versions of PRISM and PIM score used for mortality prediction in the Pediatric intensive care units (PICUs). This study aims to compare the performance of these two scores in children admitted to a tertiary PICU of South India.

Subjects and Methods:
This single-center, prospective observational study was conducted in PICU at a Tertiary Care Hospital in South India over a period of 20 months. A total of 214 cases admitted between the age groups of 1 month and 18 years were included in this study. PIM III and PRISM III scores were calculated. Quantitative correlation between the results of the score was analyzed by spearman test. Discrimination was assessed using the area under receiver operating characteristics curve and calibration using Hosmer–Lemeshow goodness-of-fit test.

Results:
Out of 214 children, observed mortality was 11 (5.1%). Estimated mortality using PRISM III and PIM III was 4 (1.86%) and 2 (0.93%), respectively. Although both scoring systems had good discrimination performance, PIM III score (0.934 [confidence interval (CI) 95%, 0.886–0.982]) had higher discrimination than PRISM III score(0.888 [CI 95%, 0.797–0.980]). PRISM III score (χ
2 = 4.469 and P = 0.484) had better calibration as compared to PIM III score (χ
2 = 16.093 and P = 0.041).

Conclusions:
Both PRISM III and PIM III score showed good discriminatory performance, however PRISM III had better calibration than PIM III score.
Anticoagulation strategies for pediatric continuous renal replacement therapy
Authors: Chidambaram Aakash Chandran , Mangla Ankit , Nallasamy Karthi 
Published: September 2024

Abstract
Continuous renal replacement therapy (CRRT) in children is quite challenging to manage because of their increased propensity for circuit clotting. The anticoagulant strategies are paramount in reducing the downtime in pediatric CRRT. The most commonly used anticoagulants in pediatrics are unfractionated heparin and citrate anticoagulation. The other less explored options include regional heparin protamine anticoagulation, prostacyclin, low-molecular-weight heparin, and thrombin antagonists. The choice of anticoagulant primarily depends on the patient’s condition, availability and cost of the anticoagulant, potential side effects, and the local expertise for troubleshooting. This article aims to bring about the merits and demerits of the different anticoagulants available for CRRT and the available evidence for the use of each of these anticoagulants.
Asiaticoside improves diabetic nephropathy by reducing inflammation, oxidative stress, and fibrosis: An in vitro and in vivo study
Authors: Zhuang Lan-Gen , Zhang Rong , Jin Guo-Xi , Pei Xiao-Yan , Wang Qiong , Ge Xiao-Xu 
Published: September 2024

BACKGROUND
Diabetic nephropathy (DN) is a severe microvascular complication of diabetes characterized by inflammation, oxidative stress, and renal fibrosis. Asiaticoside (AC) exhibits anti-inflammatory, antioxidant, and anti-fibrotic properties, suggesting potential therapeutic benefits for DN. This study aimed to investigate the protective effects of AC against DN and elucidate the underlying mechanisms involving the nuclear factor erythroid 2-related factor 2 (NRF2)/heme oxygenase-1 (HO-1) antioxidant pathway.
AIM
To investigate the renoprotective effects of AC against DN and elucidate the role of the NRF2/HO-1 pathway.
METHODS
The effects of AC on high glucose (HG)-induced proliferation, inflammation, oxidative stress, and fibrosis were evaluated in rat glomerular mesangial cells (HBZY-1) in vitro . A streptozotocin-induced DN rat model was established to assess the in vivo impact of AC on renal injury, inflammation, oxidative stress, and fibrosis. The involvement of the NRF2/HO-1 pathway was examined using pharmacological inhibition studies in the cell model.
RESULTS
AC inhibited HG-induced HBZY-1 cell proliferation and significantly improved various indicators of DN in rats, including reduced body weight, and elevated blood glucose, serum creatinine, blood urea nitrogen, and 24-h urine protein. Both in vitro and in vivo studies demonstrated that AC decreased inflammation and oxidative stress by reducing interleukin (IL)-6, IL-8, tumor necrosis factor-alpha, reactive oxygen species, and malondialdehyde levels while increasing superoxide dismutase activity. Additionally, AC suppressed the expression of fibrogenic markers such as collagen I, collagen IV, and fibronectin. AC activated NRF2 expression in the nucleus and increased HO-1 and NAD(P)H dehydrogenase (Quinone) 1 protein expression in renal tissues and HG-induced HBZY-1 cells.
CONCLUSION
AC improves DN by reducing inflammation, oxidative stress, and fibrosis through the activation of the NRF2/HO-1 signaling pathway. These findings not only highlight AC as a promising therapeutic candidate for DN but also underscore the potential of targeting the NRF2/HO-1 pathway in developing novel treatments for other chronic kidney diseases characterized by oxidative stress and inflammation.