bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brief Group Intervention Targeting Perfectionism in Adults with Anorexia Nervosa: Empirically Informed Protocol
Authors: Tchanturia Kate , Larsson Eva , Adamson James 
Published: August 2016

AbstractObjectiveThis study aimed to evaluate the perfectionism group intervention in adults with anorexia nervosa (AN) in an inpatient setting.MethodAdults with AN (N = 35) received six weekly sessions of the empirically informed intervention with experiential exercises. Participants' self‐reported perfectionism and satisfaction were collected pre‐group and post‐group intervention.ResultsStatistically, significant differences were observed for overall perfectionism, concern over mistakes and personal standard dimensions of perfectionism. Participants found the sessions useful and felt confident in using the skills they had learnt.ConclusionsThe revised perfectionism group with experiential exercises seemed to be a practical and helpful intervention for patients with AN in an inpatient programme. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.
Implementation errors in the GingerALE Software: Description and recommendations
Authors: Eickhoff Simon B. , Laird Angela R. , Fox P. Mickle , Lancaster Jack L. , Fox Peter T. 
Published: August 2016

AbstractNeuroscience imaging is a burgeoning, highly sophisticated field the growth of which has been fostered by grant‐funded, freely distributed software libraries that perform voxel‐wise analyses in anatomically standardized three‐dimensional space on multi‐subject, whole‐brain, primary datasets. Despite the ongoing advances made using these non‐commercial computational tools, the replicability of individual studies is an acknowledged limitation. Coordinate‐based meta‐analysis offers a practical solution to this limitation and, consequently, plays an important role in filtering and consolidating the enormous corpus of functional and structural neuroimaging results reported in the peer‐reviewed literature. In both primary data and meta‐analytic neuroimaging analyses, correction for multiple comparisons is a complex but critical step for ensuring statistical rigor. Reports of errors in multiple‐comparison corrections in primary‐data analyses have recently appeared. Here, we report two such errors in GingerALE, a widely used, US National Institutes of Health (NIH)‐funded, freely distributed software package for coordinate‐based meta‐analysis. These errors have given rise to published reports with more liberal statistical inferences than were specified by the authors. The intent of this technical report is threefold. First, we inform authors who used GingerALE of these errors so that they can take appropriate actions including re‐analyses and corrective publications. Second, we seek to exemplify and promote an open approach to error management. Third, we discuss the implications of these and similar errors in a scientific environment dependent on third‐party software. Hum Brain Mapp 38:7–11, 2017. © 2016 Wiley Periodicals, Inc.
Teacher Quality and Student Achievement: Evidence from a Sample of Dutch Twins
Authors: Gerritsen Sander , Plug Erik , Webbink Dinand 
Published: August 2016

SummaryThis paper examines the causal link that runs from classroom quality to student achievement using data on twin pairs who entered the same school but were allocated to different classrooms in an exogenous way. In particular, we apply twin fixed‐effects estimation to assess the effect of teacher quality on student test scores from second through eighth grade of primary education, arguing that a change in teacher quality is probably the most important classroom intervention within a twin context. In a series of estimations using measurable teacher characteristics, we find that (a) the test performance of all students improves with teacher experience; (b) teacher experience also matters for student performance after the initial years in the profession; (c) the teacher experience effect is most prominent in earlier grades; (d) the teacher experience effects are robust to the inclusion of other classroom quality measures, such as peer group composition and class size; and (e) an increase in teacher experience also matters for career stages with less labor market mobility, which suggests positive returns to on‐the‐job learning of teachers. Copyright © 2016 John Wiley & Sons, Ltd.
Competitive colonization of prosthetic surfaces bystaphylococcus aureusand human cells
Authors: Pérez‐Tanoira Ramón , Han Xia , Soininen Antti , Aarnisalo Antti A. , Tiainen Veli‐Matti , Eklund Kari K. , Esteban Jaime , Kinnari Teemu J. 
Published: August 2016

AbstractImplantation of a biomaterial provides an adhesion substratum both to host cell integration and to contaminating bacteria. We studied simultaneous competitive adhesion ofStaphylococcus aureusin serial 1:10 dilutions of 108colony forming units (CFU)/mL and human osteogenic sarcoma (SaOS‐2) or primary osteoblast (hOB) cells, both 1x105cells/mL, to the surfaces of titanium, polydimethylsiloxane and polystyrene. The bacterial adherence and human cell proliferation, cytotoxicity and production of reactive oxygen species (ROS) were studied using fluorometric (fluorescent microscopy and flow cytometry) and colorimetric methods (MTT, LDH and crystal violet). The bacterial cell viability was also evaluated using the drop plate method. The presence of bacteria resulted in reduced adherence of human cells to the surface of the biomaterials, increased production of ROS, and into increased apoptosis. On the other hand, the presence of either type of human cells was associated with a reduction of bacterial colonization of the biomaterial withStaphylococcus aureus. These results suggest that increasing colonization of the biomaterial surface in vitro by one negatively affects colonization by the other. Host cell integration to an implant surface reduces bacterial contamination, which opens novel opportunities for the design of infection‐resistant biomaterials in current implantology and future regenerative medicine. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 62–72, 2017.
Variability and trends in the Southern Hemisphere high latitude, quasi‐stationary planetary waves
Authors: Turner John , Hosking J. Scott , Bracegirdle Thomas J. , Phillips Tony , Marshall Gareth J. 
Published: August 2016

ABSTRACTWe investigate variability and trends of the Southern Hemisphere quasi‐stationary planetary waves over 1979–2013 using the European Centre for Medium‐range Weather Forecasts (ECMWF) Interim reanalyses. The effects of tropical and extra‐tropical forcing factors on the phase and amplitude of the planetary waves are identified. The amplitudes of wave numbers 1–3 exhibit an annual cycle with a minimum in summer and maximum over the extended austral winter period. The phase of wave number 1 has a semi‐annual cycle, moving east in austral spring/autumn and west in summer/winter as a result of differences in the phase of the semi‐annual oscillation across the Pacific sector of the Southern Ocean. The phase of wave number 3 has an annual cycle, being more eastward (westward) in summer (winter). Year‐to‐year variability of the amplitude of wave number 1 is found to be strongly associated with the Amundsen Sea Low, which in turn is known to be strongly influenced by the El Niño–Southern Oscillation, with the consequence that the amplitude of wave number 1 is larger during the El Niño phase of the cycle. Regarding trends for the year as a whole, the amplitude of wave number 1 has decreased since 1979 (p < 0.1), while the amplitudes of wave numbers 2 and 3 have increased. These changes are consistent with the warming trends in sea surface temperatures across much of the tropical oceans. However, the factors associated with longer‐term trends are less clear than for year‐to‐year variability.
Screen‐based color vision test for digital quantification of deutan color defects using a color‐calibrated monitor
Authors: Tsai Yi‐Chen , Chen Hung‐Shing , Luo Ronnier 
Published: August 2016

AbstractDisplay technologies are used in various industries. However, few studies on color vision testing using self‐luminous displays are reported. In this study, a screen‐based color vision test, termed the digital color vision test (DCVT), is developed on a color‐calibrated monitor. A control bar is adjusted by the observer to build just noticeable chromatic difference ellipses in CIE u′v′ chromaticity diagram, which indicate the capabilities of subjects' color visions. Ten color‐normal observers and 13 deutan observers participated in the psychophysical experiments. The observers also performed the other two typical diagnostic tests (D‐15 and anomaloscope). Results from the experiment using the adjustment psychophysical method for digital quantification of deutan color vision defects are presented. It is found that the diagnosis accuracy of the DCVT is approximately equivalent to those of D‐15 and anomaloscope tests.
Optimizing electrical impedance myography of the tongue in amyotrophic lateral sclerosis
Authors: Mcilduff Courtney E. , Yim Sung J. , Pacheck Adam K. , Rutkove Seward B. 
Published: August 2016

ABSTRACTIntroduction: Electrical impedance myography (EIM) can quantify muscle health at a range of frequencies, including that most commonly employed, 50 kHz. However, disease‐related changes in EIM data suggest the distinction between normal and patient EIM values could be more apparent at frequencies of >50 kHz. We investigated at what other selected frequencies tongue EIM may differentiate healthy individuals and amyotrophic lateral sclerosis (ALS) patients, remain reliable, and correlate with a standard metric of bulbar function. Methods: Tongue EIM phase data from 30 volunteers and 11 ALS patients were analyzed at 6 discrete frequencies from 50 to 500 kHz. Results: Of the frequencies assessed, EIM demonstrated maximal separation and reliability at 100 kHz, where phase value was also significantly correlated with the bulbar subscore on the revised version of the ALS Functional Rating Scale. Conclusions: One hundred kilohertz could serve as an optimal frequency at which to measure EIM phase values of the tongue in ALS. Muscle Nerve 55: 539–543, 2017
Dysregulated Wnt signalling and recurrent mutations of the tumour suppressor RNF43 in early gastric carcinogenesis
Authors: Min Byung‐Hoon , Hwang Jinha , Kim Nayoung KD , Park Gibeom , Kang So Young , Ahn Sangjeong , Ahn Soomin , Ha Sang Yun , Lee Yun Kyung , Kushima Ryoji , Van Vrancken Michael , Kim Min Jung , Park Changho , Park Ha Young , Chae Jeesoo , Jang Se Song , Kim Sung Jin , Kim Young‐Ho , Kim Jong‐Il , Kim Kyoung‐Mee 
Published: August 2016

AbstractSeveral recurrent mutations and epigenetic changes have been identified in advanced gastric cancer, but the genetic alterations associated with early gastric carcinogenesis and malignant transformation remain unclear. We investigated the genomic and transcriptomic landscape of adenomas with low‐grade dysplasia (LGD) and high‐grade dysplasia (HGD), and intestinal‐type early gastric cancer (EGC). The results were validated in an independent cohort that included EGCs directly adjacent to adenoma (EGC‐adenomas) that were in the process of malignant transformation, and de novo EGCs that do not seem to have been derived from adenoma. The expression patterns clearly divided into normal, LGD, and EGC, whereas those of HGD overlapped with LGD or EGC. These results suggest that HGD is the critical stage determining malignant transformation. We found that genes related to focal adhesion and extracellular matrix receptor interaction pathways were upregulated as LGD progressed to EGC, whereas canonical Wnt signalling and peroxisome proliferator‐activated receptor (PPAR) signalling pathway genes were downregulated in EGC. Genomic alterations such as somatic mutation, gene fusion and copy number variation increased gradually from LGD to EGC. APC mutations were present in 67% of LGDs, 58% of HGDs, and 18% of EGCs. RNF43 mutations were present only in HGD and EGC, and TP53 mutations were present only in EGC. In a validation cohort, RNF43 mutations were present in 35.2% of EGC‐adenomas, but in only 8.6% of de novo EGCs. This is the first study to investigate the genomic and transcriptomic landscape of multistep gastric carcinogenesis. We investigated important alterations and their related pathways in each step as tumours progressed from LGD to HGD and eventually to EGC. We suggest that mutations and downregulation of RNF43 may play a critical role in the transition from adenoma to carcinoma. Given these findings and Wnt dependency in tumours with RNF43 mutation, intestinal‐type gastric cancer or adenoma with RNF43 mutation might represent a promising indication for Wnt‐targeted agents. Copyright © 2016 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
The Rho–ROCK pathway as a new pathological mechanism of innate immune subversion in chronic myeloid leukaemia
Authors: Basbous Sara , Levescot Anaïs , Piccirilli Nathalie , Brizard Françoise , Guilhot François , Roy Lydia , Bourmeyster Nicolas , Gombert Jean‐Marc , Herbelin André 
Published: August 2016

AbstractCD1d‐restricted invariant natural killer T (iNKT) cells are believed to play a key role in cancer immune surveillance, and are functionally deficient in patients with chronic myeloid leukaemia (CML). Herein, we have hypothesized that this defect might originate from BCR‐ABL‐dependent dysfunctions in myeloid dendritic cells (mDCs). Indeed, flow cytometry and confocal microscopy revealed that cell surface expression of CD1d was downregulated in CML mDCs, relative to healthy donor (HD) controls. The decreased cell surface display of CD1d could not be ascribed to defective mDC differentiation, as attested by normal expression of HLA‐DR and the CD86 maturation marker. On the other hand, reduced membrane expression was not associated with decreased intracytoplasmic levels of CD1d or its mRNA transcripts, consistent with intracellular retention. In vitro treatment of CML mDCs with the Rho‐associated protein kinase (ROCK) inhibitor Y‐27632 partially restored both cell surface CD1d expression and CD1d‐mediated antigen presentation, whereas it had no effect on HD mDCs. An inhibitor of BCR‐ABL tyrosine kinase (TK), imatinib mesylate (IM), had no such activity. Similar recovery of CD1d expression occurred with fasudil, another ROCK inhibitor that is commonly used in clinical trials. Our data support the conclusion that BCR‐ABL‐dependent ROCK, but not TK, is involved in CD1d downregulation. We propose that ROCK, which is most likely activated by the DH/PH domain of BCR‐ABL, mediates iNKT‐cell immune subversion in CML patients by downregulating CD1d expression on CML mDCs. Our study reveals the ROCK–mDC axis as a new potential target to restore immune surveillance in patients with CML, offering new therapeutic perspectives for CML treatment. Copyright © 2016 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Global disturbance rejection for nonlinear lower triangular systems with iISS inverse dynamics and uncertain exosystem
Authors: Guo Meichen , Liu Lu , Feng Gary 
Published: August 2016

SummaryThis paper concerns about the global disturbance rejection problem for uncertain nonlinear lower triangular systems with integral input‐to‐state stable (iISS) inverse dynamics and an uncertain exosystem. The main challenges addressed in this paper include uncertain exosystem, unknown control direction, iISS inverse dynamics, and complex structure of lower triangular systems. Because of the presence of both uncertain exosystem and unknown control direction, simply combining the existing techniques for each of these challenges cannot solve the proposed problem. In fact, to handle the current case, appropriate new update laws for the estimators of the uncertain parameters are required, such that the estimators can be successfully integrated with the internal model principle. Furthermore, the changing supply function technique for iISS systems is utilized to deal with the iISS inverse dynamics. With the proposed controller, the closed‐loop system is globally asymptotically stable, and the disturbance is globally rejected. Two simulation examples are finally presented to show the effectiveness of the proposed control scheme and the practical relevance of our work. Copyright © 2016 John Wiley & Sons, Ltd.
Solvent‐ and Substituent–controlled Circularly Polarised Luminescence of C2‐symmetric Binaphthyl Fluorophores
Authors: Mizusawa Takaya , Sato Takuya , Kitayama Yoko , Tajima Nobuo , Fujiki Michiya , Imai Yoshitane 
Published: August 2016

AbstractChiral organic fluorophores have recently received growing interest in the field of chiral photoluminescence. We examined chiral binaphthyl organic fluorophores bearing phenyl substituents, observing that they exhibited fluorescence properties in solution. The sign of circularly polarizsed luminescence (CPL) of binaphthyl fluorophores was controlled by changing the solvent from the weakly polar chloroform to the highly polar dimethylformamide or methanol. Moreover, the CPL behaviour was tailored by introducing phenyl substituents into the binaphthyl unit and by replacing hydroxyl moieties with ethoxy groups.
Comparison of distribution and toxicity of different types of zinc‐based nanoparticles
Authors: Park Eun‐Jung , Jeong Uiseok , Yoon Cheolho , Kim Younghun 
Published: August 2016

ABSTRACTZinc‐based nanoparticles (Zn‐NPs), mainly zinc oxide (ZnO) NPs, have promising application in a wide area, but their potential harmful effects on environment and human health have been continuously raised together with their high dissolution rate. In this study, we coated the surface of ZnO NPs with phosphate (ZnP NPs) and sulfide (ZnS NPs) which have very low solubility in water, administered orally (0.5 and 1 mg/kg) to mice for 28 days, and then compared their biodistribution and toxicity. As expected, ZnO NPs were rapidly ionized in an artificial gastric fluid. On the other hand, ZnO NPs were more particlized in an artificial intestinal fluid than ZnP and ZnS NPs. After repeated dosing, all three types of Zn‐NPs the most distributed in the spleen and thymus and altered the level of redox reaction‐related metal ions in the tissues. We also found that three types of Zn‐NPs clearly disturb tissue ion homeostasis and influence immune regulation function. However, there were no remarkable difference in distribution and toxicity following repeated exposure of three types of Zn‐NPs, although Na+ and K+ level in the spleen and thymus were notably higher in mice exposed to ZnO NPs compared to ZnP and ZnS NPs. Taken together, we suggest that all three types of Zn‐NPs may influence human health by disrupting homeostasis of trace elements and ions in the tissues. In addition, the surface transformation of ZnO NPs with phosphate and sulfide may not attenuate toxicity due to the higher particlization rate of ZnO NPs in the intestine, at least in part. © 2016 Wiley Periodicals, Inc. Environ Toxicol 32: 1363–1374, 2017.
Managing wolves in the Yellowstone area: Balancing goals across jurisdictional boundaries
Authors: Smith Douglas W. , White P. J. , Stahler Daniel R. , Wydeven Adrian , Hallac David E. 
Published: August 2016

ABSTRACTGray wolf (Canis lupus) restoration in the Greater Yellowstone Ecosystem began in 1995 with a small founder population in Yellowstone National Park, USA, which increased and contributed to a fully restored population in the northern Rocky Mountains by 2003. Upon removal as a federally listed, threatened species, wolf management outside the park was conveyed to Idaho, Montana, and Wyoming (USA) during 2009–2012; though wolves were relisted in Wyoming in 2014. Subsequent harvests elicited substantial negative reactions from wolf advocates when wolves that lived primarily in the park moved into surrounding states and were lawfully harvested. Conversely, many game managers and hunters advocated for larger harvests of wolves, including those in the park. These divergent viewpoints merit consideration when developing management plans for wolves that move between preserves and areas where hunting is permitted. We describe the history of wolf restoration and hunting in the ecosystem, contrast National Park Service and state management objectives, and characterize the risk to wolves living primarily in the park from hunting in surrounding areas. We recommend a framework for trans‐boundary wolf management that considers population, social structure, and ecosystem objectives on public lands, potential influences of harvests on population growth, depredation risks to livestock, and opportunities for hunters and wildlife watching. We also consider human attitudes and social norms, thereby allowing for differences in values in our prescriptions. This framework has been implemented in a key hunting area along the northern boundary of Yellowstone and is broadly applicable elsewhere for the management of wildlife species held in the public trust. © 2016 The Wildlife Society.
Fat Grafting with Tissue Liquefaction Technology as an Adjunct to Breast Reconstruction
Authors: Dolen Utku , Cohen Justin B. , Overschmidt Bo , Tenenbaum Marissa M. , Myckatyn Terence M. 
Published: August 2016

Abstract

Background
Tissue liquefaction technology (TLT) delivers warmed saline from the liposuction cannula tip at low pressure pulses to disaggregate adipocytes. This technology differs significantly from that used in other liposuction devices including water jet-assisted liposuction. Here we introduce our early experience with this technology in the setting of fat transfer for revision breast reconstruction.

Methods
A retrospective chart review of 136 consecutive patients who underwent fat harvest with TLT and subsequent transfer into 237 breast reconstructions was conducted at a single institution. This two-surgeon series examined donor and recipient site complication rates over a median follow-up of 143 days [87–233].

Results
The overall complication rate was 28.7 %, of which the majority (22.1 %) was fat necrosis at the recipient site as documented by any clinical, imaging, or pathologic evidence. The abdomen served as the donor site for half of the cases. Donor site complications were limited to widespread ecchymosis of the donor site notable in 10.4 % of cases. Twenty-five percent of patients had received postmastectomy radiotherapy prior to fat transfer. Prior to revision with fat transfer, implant-based breast reconstruction was used in 75.5 % of cases, and autologous flaps in the remainder. Fat transfer was combined with other reconstructive procedures 94.1 % of the time.

Conclusions
TLT can be used to harvest adipocytes for fat transfer with donor site morbidity and recipient site complications comparable to other modalities. The efficiency and quality of harvested fat makes this technology appealing for wide spread adoption during fat transfer.

Level of Evidence IV
This journal requires that the authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.