bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors that determine the export issues in the furniture industry
Authors: Çolak Mehmet , Engin Burcu , Çetin Tahsin 
Published: December 2015

Increasing exports, to replicate the national income and by contributing to the elimination of the low income of the narrow strait in the country is supporting economic development. Export in terms of business, usage of the available physical and human resources effectively and reducement of the idle capacity, the company's growth and allows the realization of the objectives accordingly. The country's economy as much as it is for businesses as well as the export is of great importance in it. One of the most important issues for the country's economy is to ensure stability. Export is one of the permanent solutions for stability. Activities aimed at increasing the export of businesses that obtained in the study in order of importance when considered; conduct market research, to produce products of international quality standards, to increase productivity, create advertising campaigns and brand image, to participate in national and international trade fairs, continue their studies abroad by opening the office store they are stated. The sector which worked on, is mainly composed of SMEs due to the fact that in these firms such issues as marketing and promotion run within the existing possibilities/ personnels so that it leads to the inadequancy in the foreign markets. Branding of business activities abroad has reached the conclusion that inadequate. According to the challenges they face when exporting importance of business rates; lack of trained personnel, financial inability, lack of capacity, competition in the international market, consisting of the issuer expensive consulting services, providing counseling the lack of organization, so that the formalities, handling and transportation problems have emerged as significant.Keywords: furniture industry, branding, production, export issues, foreign trade
A Review of Outcomes and Modes of Presentation following Liner Dissociation from Harris-Galante Uncemented Acetabular Components
Authors: Grazette Andrew J. , Foote Julian , Whitehouse Michael R. , Blom Ashley W. 
Published: December 2015

Purpose Dissociation of the polyethylene liner is a known failure mechanism of the Harris Galante I and II uncemented acetabular components. The outcomes of revision surgery for this indication and the influence of time to diagnosis are not well described. Methods We report a series of 29 cases revised due to this failure mechanism. The median time from primary to revision surgery was 13 years. Results At a median of 4 years follow-up, the mean OHS was 34 (range 6-48) but results were poorer (mean 29; range 6-45) when the diagnosis and revision was delayed compared to when it was not (mean 39; range 20-48). A large proportion of our patients (n = 14) presented with sudden onset of symptoms with or without trauma. Osteolysis was common in this series but the cup was well fixed in 20/29 cases. There was macroscopic damage to the shell in all cases. Conclusions In our experience, prompt revision of liner dissociation optimises outcomes in this group of patients and radiology reporting alone is not sufficient to identify these cases.
Cementless Total HIP Replacements in Sickle Cell Disease
Authors: Jack Christopher M. , Howard Jo , Aziz Emad S. , Kesse-Adu Rachel , Bankes Marcus J. 
Published: December 2015

Background Sickle cell disease (SCD) affects around 80,000 people in the USA and 12,000 in the UK. Up to 40% of patients will get osteonecrosis of the femoral head. Cemented acetabular components yield poor results with the rate of osteolysis ranging from 13.5 to 46%. We report on a consecutive cohort of patients with SCD who underwent uncemented THA with ceramic-on-ceramic (CoC) bearings. Methods Since 2002 52 primary THAs were carried out in 40 patients. The average age was 36.1 years (17-54). 48 cases had exchange blood transfusion preoperatively and 3 had top-up transfusions. An S-ROM was used in 47 hips a Solutions stem in 4 hips and an AML in 1. It was necessary to drill the femur during 12 hips. There were 5 intra-operative peri-prosthetic fractures. 2 dislocations were observed. 2 superficial infections were detected. Results All components have in-grown. There have been no cases of radiographic osteolysis, migration or loosening of the hip with average 5-year (2-10.1) follow-up. Conclusions The combination of a multidisciplinary team approach and uncemented implants, with ceramic-on-ceramic bearings used, has made THA in patients with SCD a safe and reliable procedure in our hospital.
Polymorphism of Rs9387478 Correlates with Overall Survival in Female Nonsmoking Patients with Lung Cancer
Authors: Han Jie-Fei , An She-Juan , Su Wen-Mei , Chen Zhi-Hong , Su Jian , Yan Hong-hong , Guo Wei-Bang , Chen Shi-Liang , Huang Ying , Xie Zhi , Lan Qing , Rothman Nathaniel , Wu Yi-Long , Yang Jin-Ji 
Published: December 2015

Background Our previous study identified rs9387478 as a new susceptibility locus associated with lung cancer in never-smoking women in Asia; however, the clinical and prognostic significance of this finding is not known. Methods We analyzed the relationship between the rs9387478 single nucleotide polymorphism and i) clinical parameters and ii) overall survival time in 505 female nonsmoking lung cancer patients, using the chi-square test and Kaplan-Meier analysis with the log-rank test, respectively. We further established the epidermal growth factor receptor (EGFR) mutation status and assessed its association with rs9387478 genotypes as well as the efficacy of EGFR tyrosine kinase inhibitors. Results The frequency of the AA genotype was significantly higher in the EGFR-mutation-negative group than in the EGFR-mutation-positive group (32% vs. 16%, χ 2 = 13.025, p = 0.011). Patients with the CC genotype had a better overall survival time than patients with the AA/AC genotype (median survival time: 54.2 vs. 32.9 months, χ 2 = 4.593, p = 0.032). The distribution of rs9387478 genotypes differed according to the clinical disease stage. Conclusions This study indicates that the rs9387478 genotype was associated with overall survival in nonsmoking female patients with lung cancer, although it was not significant after adjusting for multiple testing. The identification of the location of the rs9387478 single nucleotide polymorphism in the genomic interval containing the DCBLD1 and ROS1 genes, together with the finding that the rs9387478 polymorphism correlates with EGFR mutation status, may have important implications for therapeutic approaches targeting EGFR or ROS1 in patients with lung cancer.
Patterns on the Embroidered Textiles Unearthed from the Silk Road Ⅱ: Geometrical Pattern
Authors: Kuang Yanghua , Cui Rongrong 
Published: December 2015

<p>Based on the archaeological evidences from the Silk Road, this paper reviews geometrical pattern on the embroidered textiles of the Han and Tang dynasties (2ndC BC-early 9thC AD). The evidences show that geometrical pattern is mainly found on textiles from Northwestern China rather than Central China. Although not widely available, it is characterized by its varied types. The regular geometrical patterns on the embroidered textiles from the Silk Road include dots, roundels, waves, whorls, triangles, diamonds, lozenges, chevrons, zigzags and crosses. As the most common motif, dots not only intersperse with other patterns or form lines as edgings but also create frames of various kinds such as roundels, diamonds and hexagons etc. then filled with other patterns. Diamonds are also common, besides serving as pattern they are often used as frames. In addition, there are examples consisting of more than one type of geometrical patterns. </p>
Techniques for Special Processing of Data within Bibliographic Text
Authors: Goossens Paula 
Published: December 2015

An analysis of the codification practices of bibliographic descriptions reveals a multiplicity of ways to solve the problem of the special processing of certain characters within a bibliographic element.
To obtain a clear insight into this subject, a review of the techniques used in different systems is given. The basic principles of each technique are stated, examples am given, and advantages and disadvantages are weighed. Simple local applications as well as more ambitious shared cataloging projects are considered.
O que vem se falando por aí em competências no ensino da promoção da saúde na formação do enfermeiro?
Authors: Silva Kênia Lara , Araújo Fernanda Lopes de , Santos Fernanda Batista Oliveira , Andrade Angélica Mônica , Basílio Nayara Caldeira , Sena Roseni Rosângela de 
Published: December 2015

O desenvolvimento de competências na formação dos profissionais de saúde tem sido discutido na literatura científica como forma de assegurar serviços de qualidade e foi tema recente de publicações importantes no cenário internacional. No entanto, o Brasil apresenta poucas experiências e produções sobre o tema. O estudo teve como objetivo analisar como são configuradas as competências para a promoção da saúde na formação do enfermeiro. Trata‑se de revisão integrativa da literatura, na qual foram incluídos oito artigos, teses e dissertações publicados a partir do ano 2000 em inglês, espanhol e português. Os descritores utilizados para a busca foram: “promoção da saúde”, “educação baseada em competências” e “competência profissional”. A análise permitiu revelar as seguintes categorias temáticas: definição de competências, competências e promoção da saúde e ensino das competências em promoção da saúde. Os achados mostram que a maior parte da literatura é de origem internacional. A maioria guarda semelhança com as competências do CompHP e Consenso de Galway e apresentam a definição de competência como a combinação de três domínios: atitude, conhecimento e habilidades. A promoção da saúde é abordada em disciplinas como saúde pública, saúde da população e políticas de saúde. Evidencia‑se que alunos vivenciam a experiência da promoção da saúde na comunidade. Ademais, a abordagem da promoção da saúde nos anos finais do curso é indicada como mais proveitosa que no início, pela maturidade (clínica e política) dos estudantes.
Effect of trace metal‐limited growth on the postmortem dissolution of the marine diatom Pseudo‐nitzschia delicatissima
Authors: Boutorh Julia , Moriceau Brivaëla , Gallinari Morgane , Ragueneau Olivier , Bucciarelli Eva 
Published: December 2015

AbstractWe investigated the effects of iron (Fe) and copper (Cu) limitations on biogenic silica (bSiO2) dissolution kinetics of the marine diatom Pseudo‐nitzschia delicatissima during a 3 week batch dissolution experiment. The dissolution of this species was faster during the first week than thereafter. Modeling results from four dissolution models and scanning electron microcopy images suggested the successive dissolution of two phases of bSiO2, with two different dissolution constants. Micronutrient limitation during growth affected the respective proportion of the two phases and their dissolution constants. After 3 weeks of dissolution, frustules from micronutrient‐limited diatoms were better preserved than those of replete cells. Our results also confirm that micronutrient‐limited cells may export more Si relative to N than replete cells and may increase the silicate pump: This may not only be due to a higher degree of silicification of the live cells but also to a decoupling between the recycling of Si and N during dissolution. We suggest that a mechanistic understanding of the evolution of the dissolution constant during dissolution is needed. This would improve the parameterization of dissolution in ecosystem models, and ultimately their predictions on the amount of bSiO2 that dissolves in the photic zone, and the amount of bSiO2 that is exported to the seafloor.
A global Mars dust composition refined by the Alpha‐Particle X‐ray Spectrometer in Gale Crater
Authors: Berger Jeff A. , Schmidt Mariek E. , Gellert Ralf , Campbell John L. , King Penelope L. , Flemming Roberta L. , Ming Douglas W. , Clark Benton C. , Pradler Irina , VanBommel Scott J. V. , Minitti Michelle E. , Fairén Alberto G. , Boyd Nicholas I. , Thompson Lucy M. , Perrett Glynis M. , Elliott Beverley E. , Desouza Elstan 
Published: December 2015

AbstractModern Martian dust is similar in composition to the global soil unit and bulk basaltic Mars crust, but it is enriched in S and Cl. The Alpha Particle X‐ray Spectrometer (APXS) on the Mars Science Laboratory Curiosity rover analyzed air fall dust on the science observation tray (o‐tray) in Gale Crater to determine dust oxide compositions. The o‐tray dust has the highest concentrations of SO3 and Cl measured in Mars dust (SO3 8.3%; Cl 1.1 wt %). The molar S/Cl in the dust (3.35 ± 0.34) is consistent with previous studies of Martian dust and soils (S/Cl = 3.7 ± 0.7). Fe is also elevated ~25% over average Mars soils and the bulk crust. These enrichments link air fall dust with the S‐, Cl‐, and Fe‐rich X‐ray amorphous component of Gale Crater soil. Dust and soil have the same S/Cl, constraining the surface concentrations of S and Cl on a global scale.
A LRSAM1 mutation links Charcot–Marie–Tooth type 2 to Parkinson's disease
Authors: Aerts Marjolein B. , Weterman Marian A. J. , Quadri Marialuisa , Schelhaas H. Jurgen , Bloem Bastiaan R. , Esselink Rianne A. , Baas Frank , Bonifati Vincenzo , van de Warrenburg Bart P. 
Published: December 2015

AbstractLRSAM1 mutations have been found in recessive and dominant forms of Charcot–Marie–Tooth disease. Within one generation of the original Dutch family in which the dominant LRSAM1 mutation was identified, three of the five affected family members have developed Parkinson's disease between ages 50 and 65 years, many years after neuropathy onset. We speculate that this late‐onset parkinsonism is part of the LRSAM1 phenotype, thus associating a hitherto peripheral nerve disease with a central nervous system phenotype. How the mutated Lrsam1 protein, which normally has E3 ubiquitin ligase activity and is expressed in the nervous system, impacts on substantia nigra neurons is unclear.
Compensatory neural mechanisms in cognitively unimpaired Parkinson disease
Authors: Poston Kathleen L. , YorkWilliams Sophie , Zhang Kai , Cai Weidong , Everling David , Tayim Fadi M. , Llanes Seoni , Menon Vinod 
Published: December 2015

ObjectiveCognitive impairments in Parkinson disease (PD) are thought to be caused in part by dopamine dysregulation. However, even when nigrostriatal dopamine neuron loss is severe enough to cause motor symptoms, many patients remain cognitively unimpaired. It is unclear what brain mechanisms allow these patients to remain cognitively unimpaired despite substantial dopamine dysregulation.MethodsThirty‐one cognitively unimpaired PD participants off dopaminergic medications were scanned using functional magnetic resonance imaging while they performed a working memory task, along with 23 controls. We first compared the PD off medication (PD_OFF) group with controls to determine whether PD participants engage compensatory frontostriatal mechanisms during working memory. We then studied the same PD participants on dopaminergic medications to determine whether these compensatory brain changes are altered with dopamine.ResultsControls and PD showed working memory load‐dependent activation in the bilateral putamen, anterior–dorsal insula, supplementary motor area, and anterior cingulate cortex. Compared to controls, PD_OFF showed compensatory hyperactivation of bilateral putamen and posterior insula, and machine learning algorithms identified robust differences in putamen activation patterns. Compared to PD_OFF, the PD on medication group showed reduced compensatory activation in the putamen. Loss of compensatory hyperactivation on dopaminergic medication correlated with slower performance on the working memory task and slower cognitive speed on the Symbol Digit Modality Test.InterpretationOur results provide novel evidence that PD patients maintain normal cognitive performance through compensatory hyperactivation of the putamen. Dopaminergic medication downregulates this hyperactivation, and the degree of downregulation predicts behavior. Identifying cognitive compensatory mechanisms in PD is important for understanding how some patients maintain intact cognitive performance despite nigrostriatal dopamine loss. ANN NEUROL 2016;79:448–463
Clickable Nucleic Acids: Sequence‐Controlled Periodic Copolymer/Oligomer Synthesis by Orthogonal Thiol‐X Reactions
Authors: Xi Weixian , Pattanayak Sankha , Wang Chen , Fairbanks Benjamin , Gong Tao , Wagner Justine , Kloxin Christopher J. , Bowman Christopher N. 
Published: December 2015

AbstractSynthetic polymer approaches generally lack the ability to control the primary sequence, with sequence control referred to as the holy grail. Two click chemistry reactions were now combined to form nucleobase‐containing sequence‐controlled polymers in simple polymerization reactions. Two distinct approaches are used to form these click nucleic acid (CNA) polymers. These approaches employ thiol–ene and thiol‐Michael reactions to form homopolymers of a single nucleobase (e.g., poly(A)n) or homopolymers of specific repeating nucleobase sequences (e.g., poly(ATC)n). Furthermore, the incorporation of monofunctional thiol‐terminated polymers into the polymerization system enables the preparation of multiblock copolymers in a single reaction vessel; the length of the diblock copolymer can be tuned by the stoichiometric ratio and/or the monomer functionality. These polymers are also used for organogel formation where complementary CNA‐based polymers form reversible crosslinks.
Cyclic (Amino)(aryl)carbenes (CAArCs) as Strong σ‐Donating and π‐Accepting Ligands for Transition Metals
Authors: Rao Bin , Tang Huarong , Zeng Xiaoming , Liu Liu Leo , Melaimi Mohand , Bertrand Guy 
Published: December 2015

AbstractCyclic (amino)(aryl)carbenes (CAArCs) result from the replacement of the alkyl substituent of cyclic (alkyl)(amino) carbenes (CAACs) by an aryl group. This structural modification leads to enhanced electrophilicity of the carbene center with retention of the high nucleophilicity of CAACs, and therefore CAArCs feature a small singlet–triplet gap. The isoindolium precursors are readily prepared in good yields, and deprotonation at low temperature, in the presence of [RhCl(cod)]2 and [(Me2S)AuCl] lead to air‐stable rhodium and gold CAArC‐supported complexes, respectively. The rhodium complexes promote the [3+2] cycloaddition of diphenylcyclopropenone with ethyl phenylpropiolate, and induce the addition of 2‐vinylpyridine to alkenes by CH activation. The gold complexes allow for the catalytic three‐component preparation of 1,2‐dihydroquinolines from aniline and phenyl acetylene. These preliminary results illustrate the potential of CAArC ligands in transition‐metal catalysis.
Synthesis and Utility of Dihydropyridine Boronic Esters
Authors: Panda Santanu , Coffin Aaron , Nguyen Q. Nhu , Tantillo Dean J. , Ready Joseph M. 
Published: December 2015

AbstractWhen activated by an acylating agent, pyridine boronic esters react with organometallic reagents to form a dihydropyridine boronic ester. This intermediate allows access to a number of valuable substituted pyridine, dihydropyridine, and piperidine products.
Environmental DNA as a monitoring tool for the endangered freshwater pearl mussel (Margaritifera margaritifera L.): a substitute for classical monitoring approaches?
Authors: Stoeckle Bernhard C. , Kuehn Ralph , Geist Juergen 
Published: December 2015

Abstract

Knowledge of species distribution is of utmost importance for conservation and management of endangered freshwater mussels. Conventional monitoring approaches are often time consuming and costly. The use of environmental DNA (eDNA) is a relatively new approach and considered as an effective tool to detect the presence of target species in aquatic environments. The aim of this study was to establish a nested PCR system to detect eDNA of Margaritifera margaritifera and to discuss the advantages and disadvantages of eDNA in mussel surveys compared with classical monitoring.
DNA of M. margaritifera was detected in 2 L water samples collected directly downstream (25 m) from pearl mussel populations (population size from 800–20 000), with an internal‐nested PCR approach greatly increasing the detection sensitivity (down to 10 fg target DNA). eDNA detection at greater distances downstream (500 and 1 000 m) of these populations failed, possibly due to DNA degradation or dilution processes. eDNA was also detected downstream of an extinct population, most likely resulting from overlooked mussels or the release of DNA from dead shells.
The eDNA approach proposed herein may be helpful in initial screening of streams that are otherwise difficult to monitor, or in the detection of buried juvenile mussels without disturbing their habitat. However, it cannot replace monitoring of population demography, and of other important information for conservation, and should thus only be seen as a supplementary tool.
Copyright © 2015 John Wiley & Sons, Ltd.
Mutations in COL1A1 Gene Change Dentin Nanostructure
Authors: Duan Xiaohong , Liu Zhenxia , Gan Yunna , Xia Dan , Li Qiang , Li Yanling , Yang Jiaji , Gao Shan , Dong Mingdong 
Published: December 2015

ABSTARCTAlthough many studies have attempted to associate specific gene mutations with dentin phenotypic severity, it remains unknown how the mutations in COL1A1 gene influence the mechanical behavior of dentin collagen and matrix. Here, we reported one osteogenesis imperfecta (OI) pedigree caused by two new inserting mutations in exon 5 of COL1A1 (NM_000088.3:c.440_441insT;c.441_442insA), which resulted in the unstable expression of COL1A1 mRNA and half quantity of procollagen production. We investigated the morphological and mechanical features of proband's dentin using atomic force microscope (AFM), scanning electron microscope, and transmission electron microscope. Increased D‐periodic spacing, variably enlarged collagen fibrils coating with fewer minerals were found in the mutated collagen. AFM analysis demonstrated rougher dentin surface and sparsely decreased Young's modulus in proband's dentin. We believe that our findings provide new insights into the genetic‐/nano‐ mechanisms of dentin diseases, and may well explain OI dentin features with reduced mechanical strength and a lower crosslinked density. Anat Rec, 299:511–519, 2016. © 2015 Wiley Periodicals, Inc.