bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel Smart Multiparametric Sensor For Pipeline Inspection – Eni UK Success Story
Authors: Passucci C. , Wolicki R. D. , Morodei F. , Arca S. , D’Alessandro E. , Leoni A. , Barile G. , Stornelli V. 
Published: October 2024

Abstract
As of today, pipelines represent the safest and the most reliable transportation solution for hydrocarbons, guaranteeing stable and replicable conditions through its whole length. However, pipeline maintenance represents a relevant cost in flow assurance in order to avoid production losses, assets damages and environmental damage. To avoid it, the detection and the localization of anomalies along the pipelines is fundamental. The integrity assessment of pipelines is expensive, invasive and not always applicable due to the harsh environment typical of pipelines, causing an increasing interest in smart and inexpensive devices for such applications. In this work we describe the performance of a novel small (45×35×24 mm) multiparametric device for pipeline inspection, which can be deployed directly into the conduct, either alone or bonded to cleaning or inspection pigs. It is equipped with long lasting battery (up to 72 h) and capable of wireless recharging and data management. The user can manage the system and collect data through dedicated software and mobile app, performing specific analysis on the data collected. The operational conditions which are suitable for the application of such device are pressure ranging from 1 to 150 bar, temperature ranging from -20 to 80°C, 3 axial accelerators ranging from 1g to 16g, 3 axial rotations ranging from 1 to 2000 dps, a sampling frequency settable from 1 to 200 Hz. The device has been enclosed in a special epoxy resin oil-proof, gas-proof and water-proof shell, capable to withstanding any kind of environment which is typical of a pipeline. It can also be equipped with an optional floating shell and thus free to flow inside the oil stream. In the end, the main benefits can be summarized in three keywords: low cost, low risk and high returns, making it ideal for large scale applications. Such device has been successfully tested in various pipeline and we’re reporting case studies, covering a total of 3500 km of pipeline in various geographic locations. We are reporting here a detailed case history of the successful application of the DeepSense device, part of ENI Technology's e-Splora™ portfolio, in an ENI UK gas pipeline. The data collected allowed for a significant optimization of the pipeline cleaning program, resulting in remarkable cost savings in pipeline maintenance activities.
Reservoir Formation Damage, Myths, Facts, and Lessons Learned From the Damage of a Deep Well in the Western Desert of Egypt
Authors: Alqutt Marwa , Sabaa Ahmed , Salem Amira , Seleem Mostafa , Abdel-Aziz Islam , Bassem Ahmed , Hussein Ahmed 
Published: October 2024

Abstract
Formation damage causes a significant loss of both short and long-term profits in the Petroleum Industry. It is the probable cause for the loss of millions of barrels of recoverable oil and billions of cubic feet of gas. Drilling and completion fluids are the first non-indigenous fluids to contact the formation; thus, it is the first opportunity for causing permeability damage. Accordingly, this paper will deal mainly with formation damage that occurs at that earliest stages.
In the Western Desert of Egypt, one of the deep wells that was drilled to 13800 ft, was initially producing from formation at 13000 ft, and due to reservoir depletion and high water cut, it was decided to abandon this interval and to produce from another potential interval which was the 1st time to be produced in Agiba. The well was perforated underbalanced and tested using test string. In order to run with the well completion string, the well was killed using NaCl–KCl filtrated and inhibited completion fluid. After the release of the workover rig, the well production decreased by almost 45%, which indicates that the reservoir was severely damaged.
Attempted to stimulate the well using several stimulation techniques to recover well production, but unfortunately, the problem worsened and well production drastically decreased. Finally, based on the results of the investigation of damage mechanism, the lower interval of the reservoir was hydraulically fractured in order to bypass the damage, as possible, to recover well production.
This paper will discuss the lessons learned from the case of deep well formation damage and will discuss the investigated damage mechanism by which the reservoir was plugged. Also, this paper will present the challenges encountered during the well recovery process, and the novel technique used to avoid introducing the damage again into the reservoir.
Operational Excellence and Multidisciplinary Integration Lead to A Cost Optimized and Timely Managed DST Operation in Newly Developed Oil Field in Gulf of Suez
Authors: Ayyad A. A. , Mohamed S. O. , Taha O. , Hashim S. , Mahmoud M. , Fawaz I. , Hasan H. , Abudooh M. , Adel A. , Elwan M. , Hamdy A. , Farag M. 
Published: October 2024

Abstract
This abstract presents a detailed case study illustrating the successful integration of multidisciplinary team members during the design, preparation and execution for a critical decision Drill Stem Test (DST) operation for a newly drilled sand body in a recently developed mega projects at Gulf of Suez Petroleum Company (GUPCO) allowing both the technical team and the management to properly select the suitable production methodology without affecting the strategic development plan for the field. The test aims to aid the decisions on whether (1) complete the well solely to the subject reservoir or not, and (2) deepen next planned wells to target the subject sand, adding around $2MM per well plus operational risk. Integration and proper tool selection were key to success, and have led to optimizing the operational rig days and thus the overall operation cost, saving the company more than $500M, without compromising on data acquisition requirements.
During the design phase, multiple-disciplinary meetings took place to communicate objectives and clarify operational procedures amongst all involved parties, including extended team from Almansoor Petroleum Services and other service companies. The team examined several options during selection of the best operational procedure and the right equipment for it. Comparison between alternative options and compatibility of different tools and equipment from different service companies was assured to generate an integrated solution without compromising the predefined job objectives. Strategic objectives and technical and operational objectives were clearly defined and assured during each stage of the journey starting from the design phase through the planning, the execution, and post job analysis and reporting.
In conclusion, this case study demonstrates that investing in efficient front-end loading, thru effective pre-planning, is good business and translates to clear value in both short- and long-terms. Also, it shows that introducing new technologies facilitate and simplify the operation saving the time and the cost. The use for robust and well integrated tools assure the results and lead to successful operation.
Using the decision trees with proper task assignment techniques and establishing a proper communication protocol among different disciplines allows a smooth operation and less miscommunications. In addition, this has set a prototype for similar jobs in Gupco in the future. Applying the DST showed the true value of information that led to saving much more money than the cost of the test itself. Pushing the technology to the limit is mandatory to gain knowledge and experience to improve the workflow for future similar operations. Establishing a methodology and developing a design philosophy sets the road for overall company development.
Statistical Analysis Plan for the “Empirical treatment against cytomegalovirus and tuberculosis in HIV-infected infants with severe pneumonia” clinical trial
Authors: Rodríguez Sara Domínguez , Lora David , Tagarro Alfredo , Moraleda Cinta , Ballesteros Álvaro , Madrid Lola , Manukyan Lilit , Marcy Olivier , Leroy Valerian , Nardone Alessandra , Burger David , Bassat Quique , Bates Matthew , Moh Raoul , Tam Pui-Ying Iroh , Mvalo Tisungane , Magallhaes Justina , Buck W.Chris , Sacarlal Jahit , Mussime Victor , Chabala Chishala , Mujuru Hilda Angela , Rojo Pablo 
Published: October 2024

Abstract

Background
The EMPIRICAL trial aims to assess safety and efficacy of an empirical treatment against cytomegalovirus (CMV) and tuberculosis (TB) compared to standard of care (SoC), on adverse events and 15-day and 1-year mortality among infants living with HIV hospitalized with severe pneumonia in Africa.
Methods and design
The EMPIRICAL trial (NCT03915366) is an international multicenter phase II-III, open-label randomized factorial clinical trial conducted in six African countries. The trial has four randomization arms in a 1:1:1:1 fashion with patients allocated to (i) TB-Treatment plus SoC, (ii) valganciclovir plus SoC, (iii) both TB-Treatment and valganciclovir plus SoC, and (iv) SoC only.
Discussion
This paper describes the statistical analysis plan (SAP) for the trial which, per the study publication plan, needs to be published prior to the database lock and final analysis results. The SAP includes details of the analyses to be undertaken and unpopulated tables that will be reported to address primary and secondary endpoints. The database will be locked on 31st January 2025.
Trial registration
ClinicalTrials.gov: NCT03915366, Universal Trial Number: U111-1231-4736, Pan African Clinical Trial Registry: PACTR201994797961340.
Post-NACA Aerodynamics: Optimizing H-Darrieus VAWT Design with CFD Simulations of J-Blades
Authors: Abdallah Ahmed , William Micheal A. , Zidane Iham F. 
Published: October 2024

Abstract

As the demand for sustainable energy sources continues to rise, improving the efficiency of existing renewable technologies is crucial. This study investigates the aerodynamic performance of a novel J-shaped blade design for H-Darrieus VAWT with the objective of enhancing starting torque and overall efficiency. A 2D URANS CFD model was employed to simulate the airflow around the J-shaped blades. The model underwent a comprehensive verification and validation process. This rigorous approach ensured the model's fidelity, enabling a systematic comparison of the J-shaped blade's aerodynamic performance with conventional NACA0015 airfoils. The numerical analysis reveals a significant enhancement in starting torque, with a 142% increase observed at low tip speed ratios (λ = 0.2). This finding positions the J-shaped blade as a promising solution to address the challenge of initiating rotation in low-wind environments, particularly relevant for urban applications. Furthermore, the simulations demonstrate comparable torque production between the J-shaped blade and the NACA0015 airfoil under typical operating conditions. The J-shaped blade exhibits improved torque uniformity and reduced wake turbulence intensity. This study highlights the potential of the J-shaped blade design to revolutionize VAWT technology by offering advancements in increased efficiency, reduced fatigue stresses on the turbine structure, and optimized energy generation.
Perspectives and experiences of parents of children with juvenile dermatomyositis: A semi-structured interview study.
Authors: Kelly Amy , Kelly Ayano , Grewal Davinder Singh , Chaitow Jeffrey , Jaure Allison 
Published: October 2024

Abstract

Background
Juvenile Dermatomyositis (JDM) is a rare, childhood inflammatory disease and its management can be challenging and confronting for both clinicians and caregivers. Little is known about the perspectives of parental caregivers of children with JDM. This study aimed to describe the experiences of parents of children with JDM to inform person-centred care.
Methods
Semi-structured interviews (face-to-face, telephone) were conducted with parents of children with JDM from three centres in Australia. Transcripts were analysed thematically.
Results
Nineteen parents (15 mothers) of 18 children aged 8 to 21 with JDM participated. Six themes were identified. Rapid crescendo of fear and desperation (alarming deterioration, sudden realisation of seriousness, desperate for a diagnosis ), lost and unsupported in the health system (at the mercy of the medical team, frustrated at the lack of services, neglected priorities, protracted and painful search for answers), disrupting family routines (sibling neglect and loss, overloaded with a medicalised schedule, always on standby, burdened by financial strains), grieving what has been lost (missing the sunlight, struggling with the loss of physical function, disrupted schooling, changes in their child from steroid side effects), managing an uncertain future (bound to chronicity, fearing relapse, insecurity with transition to adult care), gaining confidence and motivation (strengthening partnerships with clinicians, growing maturity and independence, gaining hope from shared experiences).
Conclusions
The diagnosis of JDM is often delayed and caregivers of children with JDM report distress, disruption and uncertainty throughout their treatment journey with their child. Addressing these fears and establishing support mechanisms that help parents navigate their way through the medical system and support changing family dynamics are vital to optimise health outcomes for children diagnosed with JDM.
Therapeutic effects and potential mechanisms of caffeine on obese polycystic ovary syndrome: bioinformatic analysis and experimental validation
Authors: Tonglin Bai , Yue Hu , Ling Luo , Yuhuan Liu , Chaoqin Yu 
Published: October 2024

Abstract

Background
The risk of PCOS is significantly increased in obese women, and studies have shown that weight loss can improve the symptoms of PCOS. Coffee has been shown to effectively reduce body weight. In this study, we focused on the SLC16A6 gene through bioinformatics and searched for coffee and its monomers through reverse network pharmacology.
Materials and Methods
The Gene Expression Omnibus (GEO) database was searched to screen differentially expressed genes (DEGs) with PCOS patients. Gene Ontology (GO) functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were subsequently performed. The effects of caffeine on body weight, the estrous cycle, ovarian pathology, the serum insulin concentration and the insulin resistance index, and the expression of the SLC16A6 transporter gene in the ovarian tissues of obese PCOS rats were observed.
Results
The common differentially expressed gene SLC16A6 was identified in this study, and animal experiments confirmed the effectiveness of caffeine in the treatment of obese PCOS rats.
Conclusions
Caffeine can effectively improve the symptoms of obese PCOS rats. The mechanism by which caffeine can treat obese patients with PCOS is related to increasing the expression of the SLC16A6 gene.
Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans
Authors: Greenlund Ian , Bock Joshua , Govindan Nivash , Kantas Dimitrios , Singh Prachi , Covassin Naima , Somers Virend 
Published: October 2024

Abstract

Purpose: Cardiovascular health disparities are present in African Americans, but it remains unknown whether this phenomenon affect Somali Americans. Study of Somali Americans is warranted due to distinct genetic and cultural differences from African Americans of western African ancestry. Orthostatic hemodynamic responses have implications for cardiovascular risk, especially among African American females. We sought to examine race and sex differences in systolic (SAP) and diastolic (DAP) arterial pressure and heart rate (HR) responsiveness to standing. We hypothesized that SAP, DAP, and HR change from supine to standing position would be higher in Somali Americans.
Methods: We studied blood pressure and HR responsiveness in 139 (70 Somali; age: 29±10 years, 69 White; age: 31±9 years) participants. Supine SAP, DAP, and HR were measured after at least five minutes of supine rest, and again after one minute of standing. SAP, DAP, and HR change was compared between groups.
Results: ΔSAP and ΔDAP were similar between groups (race × sex: p>0.05). However, HR responsiveness to orthostasis varied between race and sex comparisons (race×sex: p=0.011). Somali females exhibited an augmented HR response to orthostasis compared to White females (Δ19±13 vs. 11±9 beats/min, p=0.005) and Somali males (Δ19±13 vs. 12±9 beats/min, p=0.020).
Conclusion: ΔHR to standing is augmented in young female Somali Americans. These findings highlight an early potential impairment in hemodynamic regulation that may heighten future cardiovascular risk. Further work is warranted to identify the potential autonomic nervous system underpinnings that may contribute to potentiated orthostatic responses and cardiovascular risk in Somali American females.
Clinical Trial Registration: www.clinicaltrials.gov; unique identifier, NCT04124848; NCT05411029; NCT03308578.
Accelerated Accurate In-line Solder Joint Inspection Technique
Authors: Ong Teng Yeow , Tan Koon Tatt , Teoh Ping Chow , Haron Mohamad Hushnie 
Published: October 2024

Abstract

This paper reviews the entire vision inspection cycle, encompassing image acquisition, image enhancement, Region of Interest (ROI) localization and segmentation, features extraction followed by defect detection and classification. The aim of the study is to identify potential image processing time saving. The investigation innovatively suggests that optimizing image enhancement and ROI localization processing time could significantly accelerate the overall inspection cycle time without negatively impacting inspection accuracy. In Automated Optical Inspection (AOI) machine, camera sensor is mounted on precision X-Y gantries. To acquire images for inspection, the gantries will accurately move the camera to the predetermined coordinate position as stipulated in the inspection program. The vision camera will then capture the desired image using specified Field of View (FOV). Only ROI which is the solder joint position will be extracted out from the FOV image for processing. Meanwhile, the designated solder joint positions (i.e. solder pad coordinates) for all electronic components mounted on the PCB are priory known extracted from the PCB fabrication file. These coordinates can be used directly for ROI localization without employing any algorithm, and yet accuracy is not compromised. Meanwhile, through leveraging the state-of-art vision hardware, namely high-resolution camera and adaptive lighting system, quality images can be acquired and used directly without the need for any enhancement. Comparison analysis based on industrial PCB having 1000 electronics components (with 3000 solder joints of size 140x70 pixels per joint), the processing time utilizing NVIDIA GeForce RTX 2060 series Graphic Processing Unit (GPU) and Template Matching Algorithm for ROI localization needs 2 seconds. whereas when using Multiscale Morphology Algorithm for image enhancement, time required is approximately 3 seconds. Benchmarking of a typical production line with bottleneck cycle time of 25 seconds, indicating that the proposed methodology effectively addresses the challenges faced while implementing real-time machine vision inspection system in the industry, aligned with Industrial 4.0 Smart Manufacturing initiatives.
Prevalence and eradication rate of helicobacter pylori infection among the patient using the low dose of aspirin attending outpatient clinic at tertiary hospitals in Dodoma, Tanzania. A prospective longitudinal observational study
Authors: John Lawi , Sindato Emmanuel , Alphonce Baraka 
Published: October 2024

Abstract

Introduction:
Low-dose of aspirin has been widely used by health providers as primary prevention of major cardiovascular events, its benefit counterbalanced by side effects The synergistic interaction between H. pylori infection and LDA use has been identified as a significant risk factor for peptic ulcer disease, chronic gastritis, perforation, bleeding and gastric cancer with increase folds two to three times among H. pylori positive patient.
Methodology:
A prospective observational longitudinal study was carried out for patients using the low dose of aspirin attended outpatient clinic at Benjamin Mkapa Hospital and Dodoma Regional Referral Hospital in between September, 2023 to April, 2024.A sample size of 159 participants were recruited, aged 18 years or older met specified inclusion criteria. At baseline Demographic data, clinical characteristics were extracted from questionnaire form. Blood sample was collected for full blood picture and stool for H. pylori antigen test. Data analysis employing frequencies, chi-square test and binary logistic regression was done by using SPSS version 26. Statistical significance was ruled out for p < 0.05.
Results
Among 159 patients enrolled in this study, mean age was 57 (IQR 20–75), 57.7% were female. The prevalence was 74.8%. Variables which show significance in this study include use of alcohol [p value = 0.007, OR = 3.24, 95% CI (1.38–7.61)], non-adherence of medications [p value = 0.001, OR = 5.5, 95% CI (2.11–14.46)], smoking [p value < 0.001, OR = 13.61, 95% CI (2.30–56.30)].
Conclusion
H. pylori infection is frequently observed in patients using low dose of aspirin attending medical clinic to tertiary hospital in Dodoma. Factors which have significance with helicobacter pylori eradication failure were smoking, alcohol and non-adherence to medication during treatment period.
Examining the mediating role of college based capacities on the relationship between technology integration and teacher preparation program Implementation Quality in Southern Nation, Nationalities and People Region, Ethiopia
Authors: Legesse Befkadu , Legesse Dawit , Demissie Mesfin 
Published: October 2024

Abstract

The study investigated the mediating role of college-based capacities in the relationship between technology integration and implementation quality of teacher preparation programs in colleges within the South Nation, Nationalities, and Peoples region. A quantitative methods design employed, utilizing cross-sectional surveys with 294 participants from four teacher education colleges. In a study using structural equation modeling, it found that technological pedagogical content knowledge (TPACK) had a significant impact on the quality of implementation, the provision of materials, and outcomes such as instructor effectiveness. The study also revealed that college capacities, including leadership, resources, and the attitudes of diploma graduates, played a mediating role in the relationship between technology integration and implementation quality. Correlation analysis showed strong positive relationships between technology integration, and factors such as instructor efficacy, leadership support, resource availability, and attitudes toward technology integration. The findings highlight technology integration significance to the proposed model and its interconnectedness with organizational and human elements influencing effective technology use in teacher education. Theoretically, the results align with resource-based and transformational leadership theories, emphasizing strategic resource utilization and leadership practices enhancing teaching and learning through technology. Practically, a comprehensive approach investing in TPACK competencies, instructional leadership, and resource provision recommended for impactful educational reforms. The study contributes an original model clarifying the dynamics between technology integration, college capacities, and implementation quality in teacher preparation contexts.