bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early and Late Complications Following Dynamic Stereotactic Radiosurgery and Fractionated Stereotactic Radiotherapy
Authors: Michal R. McKenzie , Luis Sohami , Jean-Louis Caron , Andre Oliver , Jean-Guy Villemure , Ervin B. Podgorsak 
Published: February 2016

ABSTRACT:Between December 1986 and June 1990, 112 patients (116 lesions), underwent treatment with dynamic stereotactic radiosurgery at McGill University. Of the treated lesions, 59 were arteriovenous malformations and 53 were a variety of other neoplastic or non-neoplastic conditions. In 86 lesions, the treatment was delivered in a single fraction and the treatment of the remaining 30 lesions was fractionated. Complications attributed to treatment developed in seven of the 112 patients (6.3%). No relationship was found between complications and prescribed dose, fractionation, collimator diameter, type and anatomical region of the lesion that was treated, or previous irradiation. Although extensive clinical experience will be necessary to determine optimal total doses, the potential role of fractionated treatment, and the tolerance of critical structures to radiosurgery, the relatively low incidence of complications in our series allows us to conclude that radiosurgery is well tolerated by the vast majority of patients.
Hemiballism-hemichorea Induced by Subcortical Ischemia
Authors: Toshiya Fukhi , YuKihiro Hasegawa , Shinya Seriyama , Toru Takeuchi , Koujiro Sugita , Hiroshi Taukagoshi 
Published: February 2016

ABSTRACT:Four patients presented with hemiballism-hemichorea as a clinical manifestation of white matter ischemia. These patients illustrate “positive” motor phenomena rather than limb weakness as a consequence of cerebral ischemia. In each patient, the involuntary movements disappeared following worsening of paresis. Subcortical white matter infarction in three patients and hemodynamic hypo-perfusion in the cerebral hemisphere contralateral to dyskinetic movements were possible causes. Neuroradiologically, none had pathological changes in the vicinity of the subthalamic nucleus. We presume from these observations that ischemia of the subcortical white matter, without involvement of the basal ganglia or the subthalamic nucleus, may cause hemiballism-hemichorea
William M. Lougheed and the Development of Vascular Neurosurgery at the Toronto General Hospital
Authors: Max Findlay J. 
Published: February 2016

ABSTRACT:Dr. Bill Lougheed was able to navigate residents through even the most complex neurosurgical procedures with complete and often heroic patience, always ensuring for the patient his usual expert technical result but still leaving intact the resident’s sense of pride and achievement, the feeling that he, the resident, “had done it”. A gifted technical surgeon, a thoughtful and inventive neurosurgeon, Dr. Lougheed was above all else one of Canada’s great teachers of operative neurosurgery. Canada’s pioneer microneurosurgeon, Dr. Lougheed brought the Toronto General Hospital to the very forefront of the emerging field of vascular neurosurgery.
Denis Naldrett White, M.A., M.D., F.A.C.R, F.R.C.P.C. (1916-1993)
Authors: Henry B. Dinsdale 
Published: February 2016

ABSTRACT:Denis Naldrett White was born in Bristol. He completed his premedical and medical education at Cambridge. This was followed by graduate training at the London Hospital with Russell Brain, Hospital for Sick Children, National Hospital for Nervous Diseases and the Institute of Psychiatry, University of London, where he completed a senior registrar post in 1948. That same year he was recruited by Dr. Ford Connell, Head of the Department of Medicine, to Queen’s University.
Structural and Molecular Compartmentation in the Cerebellum
Authors: Richard Hawkes , Steven Blyth , Vijay Chockkan , David Tano , Zhongqi Ji , Christa Mascher 
Published: February 2016

ABSTRACT:Most descriptions treat the cerebellum as a uniform structure, and the possibility of important regional heterogeneities in either chemistry or physiology is rarely considered. However, it is now clear that such an assumption is inappropriate. Instead, there is substantial evidence that the cerebellum is composed of hundreds of distinct modules, each with a precise pattern of inputs and outputs, and expressing a range of molecular signatures. By screening a monoclonal antibody library against cerebellar polypeptides we have identified antigens – zebrins – that reveal some of the cerebellum’s covert heterogeneity. This article reviews some of these findings, relates them to the patterns of afferent connectivity, and considers some possible mechanisms through which the modular organization may arise.
Cerebellar Dysfunction of Movement and Perception
Authors: Diener H.C. , Hore J. , Ivry R. , Dichgans J. 
Published: February 2016

ABSTRACT:This review describes some characteristics of patients with cerebellar lesions, including limb movements, changes in motor planning and disturbances in time-dependent perception. The delay in movement initiation can be explained by a delay in onset of movement-related discharge of neurons in motor cortex. Disorders of movement termination (hypermetria) are accompanied by asymmetric velocity profiles and by prolonged agonist and delayed antagonist EMG activity necessary to brake the movement. During complex movements in three-dimensional space, the cerebellum contributes to timing between single components of a movement, scales the size of muscular action, and coordinates the sequence of agonists and antagonists. The basic structure of motor programs is not generated exclusively within the cerebellum and patients with cerebellar lesions can use precuing information to improve their motor performance. Time-dependent perception in the auditory and visual domains are disturbed in patients with cerebellar lesions.
A Proposal for Classification of Neurocysticercosis
Authors: Carpio Arturo , Placencia Marcelo , Santillán Franklin , Escobar Alfonso 
Published: February 2016

ABSTRACT:The complicated pathophysiological and immunological changes in the central nervous system of patients with neurocysticercosis produce a variety of signs and symptoms, which complicate the clinical and surgical management of this disease. A complete and objective classification is needed, to improve the medical approach as a whole. We studied 336 patients, in whom we classified neurocysticerosis according to criteria of viability and location of the parasite in the CNS: active form (37.2%) when the cysticercus is alive, transitional form (32.8%) when it is in the degenerative phase, and inactive form (30%) when the parasite is dead. This classification establishes the correlation between the different forms of neurocysticerosis and its clinical manifestations, and can be used for planning therapeutic strategies.
Gilles de la Tourette Syndrome – Review Article
Authors: Suchowersky O. 
Published: February 2016

ABSTRACT:Gilles de la Tourette syndrome is a neurological disorder characterized by the presence of motor and vocal tics. Other associated features include complex motor and vocal tics, obsessive compulsive behavior and attention-deficit disorder. Although initially thought to be a rare condition, it now appears that the gene for Tourette syndrome may be present in as many as one in a thousand people, and is transmitted as an autosomal dominant trait. However, many individuals carrying the gene may exhibit only minimal symptoms. Neuropathophysiology of Tourette syndrome is unknown but investigations have suggested that the cause may be an abnormality either in the dopaminergic or endorphin receptor system within the basal ganglia. Treatment of Tourette syndrome involves education and counseling of the patient and family. Medications such as neuroleptics, serotonin-reuptake inhibitors, and stimulants are available to treat the manifestations of Tourette syndrome and need to be individualized for each patient.
Acute Transverse Myelitis: A Retrospective Study Using Magnetic Resonance Imaging
Authors: Scott Thomas , Weikers Norbert , Hospodar Mark , Wapenski Joseph 
Published: February 2016

Abstract:The prognostic value of magnetic resonance imaging (MRI) in the syndrome of acute transverse myelitis had not been evaluated. After retrospective study of 14 cases, we found that MRI is valuable for both diagnosis and prognosis in this illness. The criteria for the diagnosis of acute transverse myelitis consisted of acute onset (over less than 3 weeks) of symmetrical motor and sensory dysfunction referable to a distinct spinal cord level, with sphincter dysfunction. Patients with abnormal MRIs of the spinal cord had significantly worse outcomes than patients with normal MRIs.
Introduction to the Guideline, and General Principles of Acute Migraine Management
Authors: Worthington Irene , Pringsheim Tamara , Gawel Marek J. , Gladstone Jonathan , Cooper Paul , Dilli Esma , Aube Michel , Leroux Elizabeth , Becker Werner J. ,   on behalf of the Canadian Headache Society Acute Migraine Treatment Guideline Development Group
Published: February 2016

ABSTRACT:Objectives:To provide an overview of the objectives and target population of the guideline, and to review the general principles of acute pharmacological migraine therapy.Methods:A general literature review and several consensus groups were used to formulate an expert consensus for the general use of acute migraine medications.Results:The objective of the guideline is to assist the physician in choosing an appropriate acute migraine medication for an individual with migraine, and thereby to reduce migraine-related disability. The target population includes adults with episodic migraine (patients with migraine headache < 15 days/month). This guideline is intended primarily for physicians who treat patients with migraine. Other health professionals may also find this guideline helpful. Acute migraine therapy should be considered for the great majority of patients with migraine. A specific acute medication is chosen based on evidence for efficacy, tolerability, migraine attack severity, patient preference, and on the presence of co-existing disorders. General principles of acute migraine therapy include that the response of a patient to any given medication cannot be predicted with certainty, and that treatment early in the attack is generally more effective than treatment later once the migraine attack is fully developed. A suitable treatment approach (stratified or stepped approaches) and drug formulation (injection, tablet, wafer, powdered formulation, or nasal spray) should be chosen based on patient clinical features. Excessively frequent use of acute medications (medication overuse) should be avoided. Two or more acute medications can be combined if necessary.Conclusions:This guideline provides evidence-based advice on the use of acute medications for migraine, and should provide useful guidance for acute migraine therapy to both health professionals and patients.
Targeted Review: Medications for Acute Migraine Treatment
Authors: Worthington Irene , Pringsheim Tamara , Gawel Marek J. , Gladstone Jonathan , Cooper Paul , Dilli Esma , Aube Michel , Leroux Elizabeth , Becker Werner J. ,   on behalf of the Canadian Headache Society Acute Migraine Treatment Guideline Development Group
Published: February 2016

ABSTRACT:Objective:To assess the evidence base for drugs used for acute treatment of episodic migraine (headache on < 14 days a month) in Canada.Methods:A detailed search strategy was employed to find relevant published clinical trials of drugs used in Canada for the acute treatment of migraine in adults. Primarily meta-analyses and systematic reviews were included. Where these were not available for a drug or were out of date, individual clinical trial reports were utilized. Only double-blind randomized clinical trials with placebo or active drug controls were included in the analysis. Recommendations and levels of evidence were graded according to the principles of the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group, using a consensus group.Results:Eighteen acute migraine medications and two adjunctive medications were evaluated. Twelve acute medications received a strong recommendation with supporting high quality evidence for use in acute migraine therapy (almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan, ASA, ibuprofen, naproxen sodium, diclofenac potassium, and acetaminophen). Four acute medications received a weak recommendation for use with low or moderate quality evidence (dihydroergotamine, ergotamine, codeine-containing combination analgesics, and tramadol-containing combination analgesics). Three of these medications were NOT recommended for routine use (ergotamine, and codeine- and tramadol-containing medications), and strong recommendations were made to avoid use of butorphanol and butalbital-containing medications. Both metoclopramide and domperidone received a strong recommendation for use with acute migraine attack medications where necessary.Conclusion:Our targeted review formulated recommendations for the available acute medications for migraine treatment according to the GRADE method. This should be helpful for practitioners who prescribe medications for acute migraine treatment.
Post Second World War Immigration from Balkan Countries to Turkey
Authors: Kirişçi Kemal 
Published: February 2016

One of the important consequences of the end of the Cold War has been the growing impact that ethnicity has had on the domestic politics of countries as well as international politics. An area that has been deeply affected by ethnopohtics is the Balkans. The collapse of communism and the disintegration of Yugoslavia have led to tremendous instability and ethnic strife in the Balkans. Turkey's domestic politics as well as its foreign policy have been deeply affected by these developments. One reason for this can be attributed to the fact that in Turkey there are large numbers of people of Balkan descent.As the frontiers of the Ottoman Empire in the Balkans began to contract, large numbers of people who identified themselves with the Empire steadily migrated to Thrace and Anatolia. They were mostly the descendants of Turks who had settled in various parts of the Balkans during the past centuries (Karpat 1985, ch.4). Although there are no exact figures, one source puts the size of this migration between late 1870s and early 1920s at as high as 1,445,000 (Eren 1993, p. 298). In spite of this massive migration many Turkish and Muslim communities were left behind in various parts of the Balkans after the collapse of the Ottoman Empire. The modern Turkish State has continued to allow members of these communities to migrate and settle in Turkey.
Homemaker or professional? Girls' schools designed by Ernst Egli and Margarete Schütte-Lihotzky in Ankara, 1930-1938
Authors: Kılınç Kıvanç 
Published: February 2016

AbstractDuring the early years of the Turkish Republic, modern architecture became an active tool in the representation of the bourgeois ideal of domesticity. The most significant component of the new Turkish family was the image of the “republican woman” as a nationally-constructed icon. By comparatively examining Ernst Egli's İsmet Paşa Girls' Institute (1930) and Ankara Girls' High School (1936) with Margarete Schütte-Lihotzky's unbuilt annex project for the latter (1938) this paper argues that girls' technical schools and girls' high schools contributed to the making of this much idealized image in considerably different ways. Such diversity enabled the governing elite in Turkey to make a class-based and spatially constructed categorization of women as economic actors: enlightened housewives specialized in one of the so-called “female arts” and upper-class professional women who would participate in public life. It is further argued that this categorization allowed Schütte-Lihotzky, in her design for the unbuilt high school annex in Ankara, to rework the broader “redomestication” issue which marked her earlier career in Weimar Germany.
Peripheral Port-Cities and Politics on the Eve of the Great War
Authors: Keyder Çağlar 
Published: February 2016

Est-ce donc vers le passé qu'il regardait, plutôt que vers l'avenir? Il n'est pas facile de trancher. Après tout, l'avenir est fait de nos nostalgies, de quoi d'autre?Cet âge où les hommes de toutes origines vivaient côte à côte dans les Echelles du Levant et mélangeaient leurs langues, est-ce une réminiscence d'autrefois? est-ce une préfiguration de l'avenir? Ceux qui demeurent attachés à ce rêve sont-ils des passéistes ou bien des visionnaires? Je serais incapable de répondre. Mais c'est en cela que mon père croyait. En un monde couleur sépia oû un Turc et un Arménien pouvaient encore être frères.Maalouf 1996, p. 49
Athens, Constantinople, “Istambol”: Urban Paradigms and Nineteenth-Century Greek National Identity
Authors: Fleming K. E. 
Published: February 2016

Your nostalgia has createdA nonexistent country, with lawsAlien to earth and man.George Seferis,The Return of the Exile(Keeley and Sherrard, 1981, pp. 224-25)The history of Greece's first century as an independent nation-state is in many ways a history of the interplay among urban space, nationalism, and identity. It is also a history of nostalgia: Western European nostalgia for one specific past, Greek nostalgia for another, and the tension between the two.
Cezayir-i Garp: Bringing Algeria back into Ottoman History
Authors: Shuval Tal 
Published: February 2016

Little is known even now of the history of Algeria under the Turks; it is a period which has not aroused much interest.- M. ColombeIn this study I propose to outline the political history of Cezayir-i Garp, the Ottoman province of Algeria, during the seventeenth century, while at the same time noting the correspondence between this history and the various developments at the center of the Ottoman Empire as well as in some of the provinces. This similarity suggests that Ottoman rule in Algeria was influenced by the same factors that affected the rest of the Empire. The pattern of development of the province's Ottoman elite, and the nature of this elite's behavior, reinforce its position within the imperial framework, even in periods when it was considered to be on a divergent path. My argument is that the history of the Ottoman province of Algeria was an integral part of an imperial pattern and structure forged by complex and dynamic relations between the imperial capital and its provinces.
Group-Differentiated Rights and the Liberal Democratic State: Rethinking the Headscarf Controversy in Turkey
Authors: Arat Yeşim 
Published: February 2016

The development of liberalism with both the courage and the capacity to engage itself with a different world, one in which its principles are neither well understood nor widely held, in which indeed it is, in most places, a minority creed, alien and suspect, is not only possible, it is necessary.-Clifford Geertz. 2000.Available Light.Princeton, N.J.: Princeton University Press, p. 258.Over the past two decades, the debate over multiculturalism challenged the justice of neutral, “difference blind” rules in liberal democracies. Allegedly neutral institutions were shown to be implicitly biased toward the priorities, experiences, or interests of the dominant groups in the society. Criticism of difference-blind rules and claims for justice to minority groups defined the relationship between government and opposition in many contexts. Arguments for special rights to protect minorities, women, or ethnocultural groups gained legitimacy (Young 1990, Jones 1990, Phillips 1991, Taylor 1994, Kymlicka 1995, Kymlicka and Norman 2000).
The Lost Lullaby and Other Stories about Being an Armenian in Turkey
Authors: Bilal Melissa 
Published: February 2016

Nınçir mangig im sirasun, Oror yem asum, Baydzar lusinn e meğm hayum, Ko ororotsum.By analyzing the transmission of Armenian lullabies within the changing contexts of identity and cultural politics in Turkey, this paper addresses displacement and loss as two interrelated experiences shaping the sense of being an Armenian in Turkey. I criticize the liberal multiculturalist perspective that represents cultures in a way that cuts the link between the past and the present, by dissociating different cultures from the history of their presence in Anatolia and the destruction of that presence. I argue that in such a context where cultures are detached from lived experiences and memory, it becomes impossible to share the stories of violence and pain in the public sphere; hence, the loss itself becomes the experience of being Armenian. Finally, I try to explain how today young generations of Armenians in İstanbul, in their search for an Armenian identity, have developed a certain way of belonging to the space and culture, a way of belonging that is very much shaped by the experience of loss.
Emerging Spaces of Neoliberalism: A Gated Town and a Public Housing Project in İstanbul
Authors: Bartu Candan Ayfer , Kolluoğlu Biray 
Published: February 2016

Abstractİstanbul has undergone a neoliberal restructuring over the past two decades. In this paper, we focus on two urban spaces that we argue to have emerged as part of this process—namely Göktürk, a gated town, and Bezirganbahçe, a public housing project. We examine these spaces as showcases of new forms of urban wealth and poverty in İstanbul, demonstrating the workings of the neoliberalization process and the forms of urbanity that emerge within this context. These are the two margins of the city whose relationship with the center is becoming increasingly tenuous in qualitatively different yet parallel forms. In Göktürk's segregated compounds, where urban governance is increasingly privatized, non-relationality with the city, seclusion into the domestic sphere and the family, urban fear and the need for security, and social and spatial isolation become the markers of a new urbanity. In Bezirganbahçe, involuntary isolation and insulation, and non-relationality with the city imposed through the reproduction of poverty create a new form of urban marginality marked by social exclusion and ethnic tensions. The new forms of wealth and poverty displayed in these two urban spaces, accompanied by the social and spatial segregation of these social groups, compel us to think about future forms of urbanity and politics in İstanbul.
Power or Leisure? Remarks on the Architecture of the European Summer Embassies on the Bosphorus Shore
Authors: Girardelli Paolo 
Published: February 2016

AbstractThis study is part of a larger project on theLandscapes of the Eastern Question, contextualizing the architecture of diplomacy in İstanbul as a symbolic and material refraction of changing power balances and representational strategies. In Beyoğlu, where most of the main diplomatic residences were located, the embassies were originally Ottoman woodenkonakstructures, but, in time, the increasing influence of Russia, Great Britain and France fostered their monumentalization and the adoption of European academic classicism. By contrast, the summer embassies on the European shore of the Bosphorus remained largely local in terms of technology, image, materials, and spatial layout until the end of the Ottoman Empire. The paper argues that, for many diplomats, a stately winter residence representing national identity, along with a summer house in the spirit of the local traditions, would be used as a communicative and performative resource in the drama of European-Ottoman relations. It also evaluates foreign settlement on the northern shore of the Bosphorus as conforming to a strategy of surveillance and control in keeping with the strategic relevance and contested status of the straits.