bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photoprotective Potential of Baccharis antioquensis (Asteraceae) as Natural Sunscreen
Authors: Mejía‐Giraldo Juan C. , Winkler Robert , Gallardo Cecilia , Sánchez‐Zapata Ana M. , Puertas‐Mejía Miguel A. 
Published: July 2016

AbstractIn the quest for new natural agents of photoprotection, we evaluated the photoprotective and antioxidant activity of B. antioquensis leaf extracts as well as its phenolic composition. The methanolic extract treated with activated carbon showed the highest absorption coefficients for UVA‐UVB radiation, as well as an antioxidant capacity comparable to butylated hydroxy toluene. Furthermore, the formulation containing this extract showed suitable sensorial and photostable characteristics for topical use, and significant values of UVAPF, critical wavelength (λc), UVA/UVB ratio and sun protection factor (5.3, 378 nm, 0.78 and 9.1 ± 0.1, respectively). In addition, three glycoside derivatives of quercetin, a kaempferol glycoside and a derivative of caffeic acid were the main polyphenolic compounds identified. These results demonstrate the potential of B. antioquensis extracts to be used as active components of novel, natural sunscreens.
Clinical features, aetiology and outcome of bacteraemic pneumonia in neutropenic cancer patients
Authors: Gudiol Carlota , Royo‐Cebrecos Cristina , Laporte Júlia , Ardanuy Carmen , Garcia‐Vidal Carolina , Antonio Maite , Arnan Montserrat , Carratalà Jordi 
Published: July 2016

ABSTRACTBackground and objectiveWe aimed to assess the clinical features, aetiology and outcomes of bacteraemic pneumonia in neutropenic cancer patients (NCP) in the current era of increasing antimicrobial resistance.MethodsAll episodes of bacteraemia occurring in hospitalized patients with cancer, including haematopoietic stem cell transplant recipients, from January 2006 to April 2015 were included.ResultsWe identified 1723 episodes of bacteraemia, of which 795 occurred in neutropenic patients with cancer, and among them, 55 episodes were identified as bacteraemic pneumonia. The most frequent causative agents were Pseudomonas aeruginosa (39.6%), Streptococcus pneumoniae (20.6%) and Escherichia coli (8.6%). Among the Gram‐negative organisms, 12.8% were multidrug resistant (MDR). Eleven patients (20%) required admission to intensive care, and eight (14.8%) underwent invasive mechanical ventilation. Nine patients (16.3%) received inadequate empirical antibiotic therapy, of whom six (66.6%) died; eight of these nine patients had pneumonia caused by resistant microorganisms. The early (48 h) case‐fatality rate was 24% and the overall (30 day) case‐fatality rate was 46.2%.ConclusionBacteraemic pneumonia is a frequent complication among NCP and is mainly caused by P. aeruginosa and S. pneumoniae. The emergence of MDR organisms is of special concern. Despite the improvement in the management of cancer patients, case‐fatality rates of NCP with bacteraemic pneumonia remain high. Urgent assessment is needed to identify a better approach for the management and support of these patients.
Parents' perception of dental caries in intellectually disabled children
Authors: Weckwerth Solange Aparecida Modesto , Weckwerth Giovana Maria , Ferrairo Bunna Mota , Chicrala Gabriela Moura , Ambrosio Alexandre Macedo Batitucci , Toyoshima Guilherme Hideki Lima , Bastos José Roberto Magalhães , Pinto Edu Cassiano , Velasco Sofia Rafaela Maito , Bastos Roosevelt Silva 
Published: July 2016

ABSTRACTThe aim of this study was to evaluate the parents’ perception of dental caries in children with intellectual disability. This cross‐sectional study was conducted with 6 to 14 years old schoolchildren: Group 1 (50 children diagnosed with intellectual disabilities) and Group 2 (50 children without it). The dental caries was assessed by the World Health Organization (WHO) criteria for primary and permanent teeth. Parents’ psychosocial perception was assessed by Early Childhood Oral Health Impact Scale (ECOHIS). Similar prevalence of caries free children was found between groups in both dentitions. In primary dentition the caries index was higher in Group 2, and the opposite occurred in permanent teeth. Group 1 presented higher impact (p < .05) in the dimension drinking, eating and pronunciation, whereas in Group 2 there was higher impact (p = .01) on pain, sleep, irritation, the smile and family finances. Findings showed significant impact of dental caries on parents’ perception of the oral health related quality of life of children with intellectual disabilities.
Presence of HLA‐DR Molecules and HLA‐DRB1 mRNA in Circulating CD4+ T Cells
Authors: Revenfeld A. L. S. , Steffensen R. , Pugholm L. H. , Jørgensen M. M. , Stensballe A. , Varming K. 
Published: July 2016

AbstractThe human major histocompatibility complex class II isotype HLA‐DR is currently used as an activation marker for T cells. However, whether an endogenous protein expression or a molecular acquisition accounts for the presence of HLA‐DR on T cells remains undetermined and still controversial. To further characterize this phenomenon, we compared several aspects of the presence of the HLA‐DR protein to the presence of associated mRNA (HLA‐DRB1), focusing on human T cells from peripheral blood of healthy individuals. Using a flow cytometric approach, we determined that the HLA‐DR observed on CD4+ T cells was almost exclusively cell surface‐associated, while for autologous CD19+ B cells, the protein could be located in the plasma membrane as well as in the cytoplasm. Moreover, negligible expression levels of HLA‐DRB1 were found in CD4+ T cells, using an HLA‐DRB1 allele‐specific qPCR assay. Finally, the presence of HLA‐DR was not confined to activated CD4+ and CD8+ T cells, as evaluated by the co‐expression of CD25. The functional role of the HLA‐DR molecule on T cells remains enigmatic; however, this study presents evidence of fundamental differences for the presence of HLA‐DR on T cells from HLA‐DR in the context of antigen‐presenting cells, which is a well‐known phenomenon. Although an inducible endogenous protein expression cannot be excluded for the T cells, our findings suggest that a re‐evaluation of the HLA‐DR as a T cells activation marker is warranted.
Belongingness and Burdensomeness in Adolescents: Slovene Translation and Validation of the Interpersonal Needs Questionnaire
Authors: Podlogar Tina , Žiberna Janina , Poštuvan Vita , C. R. Kerr David 
Published: July 2016

The Interpersonal Needs Questionnaire (INQ) for assessing thwarted belongingness (TB) and perceived burdensomeness (PB) has not been validated with community adolescents. We translated and administered the INQ to 307 Slovenian adolescents twice over 2–3 months and found that the 15‐item version (INQ‐15) did not fit without modification. TB and PB scales correlated with concurrent and later suicide ideation and lifetime suicide attempt history. The latent PB factor was associated with concurrent and later ideation controlling for TB, age, gender, depressive symptoms, binge drinking, and peer victimization. Suicide ideation and binge drinking were independently related to attempt history. Assessing and intervening on PB and binge drinking may be promising approaches to suicide prevention with community adolescents.
Is There a Relationship between Suicidal Intent and Lethality in Deliberate Self‐Poisoning?
Authors: Gjelsvik Bergljot , Heyerdahl Fridtjof , Holmes Jane , Lunn Daniel , Hawton Keith 
Published: July 2016

The relationship between suicidal intent and lethality of deliberate self‐poisoning (DSP) episodes and their associations with suicide have yielded contradictory findings. The aims of this study were to investigate the association between patients’ suicidal intent and independently rated lethality of DSP episodes, and whether the association changes over time. Eighty‐nine DSP patients were investigated longitudinally. Self‐reported suicidal intent, including perceived likelihood of dying, wish to die, and whether or not the DSP was considered a suicide attempt, was measured at the time of the index episode (t1), 3 months (t2), and 12 months (t3) later. Lethality was assessed independently by three clinical toxicologists. Lethality was significantly associated with patients’ reported wish to die (p = .01) and perceived likelihood of dying (p = .04) at t1, but not at t2 and t3. No association was found between whether the episode was considered a suicide attempt or not and lethality at t1, t2, or t3. Lethality and suicidal intent should be considered as largely separate dimensions of self‐harm. Clinicians should bear this in mind during clinical assessment, especially regarding historical information.
Individual and combined effects of acute and chronic running loads on injury risk in elite Australian footballers
Authors: Murray N. B. , Gabbett T. J. , Townshend A. D. , Hulin B. T. , McLellan C. P. 
Published: July 2016

A model that takes into account the current workload, and the workload the athlete has been prepared for, as an acute:chronic workload ratio has been previously used as a novel way to monitor training load and injury risk. Fifty‐nine elite Australian football players from one club participated in this 2‐year study. Global Positioning System technology was used to provide information on running workloads of players. An injury was defined as any non‐contact “time‐loss” injury. One‐week (acute), along with 4‐week (chronic) workloads were calculated for a range of variables. The size of the acute workload in relation to the chronic workload was calculated as an acute:chronic workload ratio. An acute:chronic workload ratio of >2.0 for total distance during the in‐season was associated with a 5 to 8‐fold greater injury risk in the current [relative risk (RR) = 8.65, P = 0.001] and subsequent week (RR = 5.49, P = 0.016). Players with a high‐speed distance acute:chronic workload ratio of >2.0 were 5–11 times more likely to sustain an injury in the current (RR = 11.62, P = 0.006) and subsequent week (RR = 5.10, P = 0.014). These findings demonstrate that sharp increases in running workload increase the likelihood of injury in both the week the workload is performed, and the subsequent week.
Water Policy And Governance Networks: A Pathway To Enhance Resilience Toward Climate Change
Authors: Caniglia Beth , Frank Beatrice , Kerner Bridget , Mix Tamara L. 
Published: July 2016

AbstractNatural resources governance is key to enhancing resilience toward climate change and strengthening socioecological systems in light of future uncertainties. Overlapping jurisdictions and lack of clarity in the lines of authority reduce the efficiency of environmental policies and governance, jeopardizing the conservation and sustainable use of resources. With the forecast of longer droughts, extreme precipitation patterns, faster runoff, and slower water table recharge over the coming years, water governance becomes an impellent issue. To understand the risks posed by water scarcity and water regulations, a case study was conducted of Oklahoma state‐level water policies and governance. A content analysis of water policies and a network analysis of water governance was used to determine how Oklahoma experiences features of fragmented and adaptive governance within its natural resource governance structure. Data analysis reveals that Oklahoma water governance experiences multiple forms of fragmentation while also showing features of an adaptive network. Such adaptive features make Oklahoma's water governance network more resilient than forecasted. Identifying gaps and understanding how a governance system experiences fragmentation can help policy makers develop strategies to enhance the adaptive features of water governance, thus preparing for risk and disasters related to water scarcity and climate variability.
Subpartisan Cues and Ideological Distinctions: The Effect of the Tea Party Label on Voter Perceptions of Congressional Candidates*
Authors: Gervais Bryan T. , Taylor Jeffrey A. 
Published: July 2016

ObjectiveWe aim to fill a gap in the voter heuristic literature by estimating the impact of subparty cues—labels that connect candidates to an intraparty faction—on perceptions of candidates’ ideological positions. We argue that the Tea Party label acts as a subpartisan cue, and should affect perceptions of both Republicans and their Democratic opponents.MethodsWe measure ideological perceptions using data from the Cooperative Congressional Election Study (CCES), and measure Tea Party “saliency” based on how often candidates were linked with the Tea Party in news media. Using probit regression, we estimate the impact of Tea Party saliency on ideological perceptions of candidates.ResultsWe find that Republican candidates often associated with the Tea Party are more likely to be perceived as conservative or very conservative, even when we control for candidate and voter ideology, while their Democratic opponents are perceived to be more moderate.ConclusionThe results suggest that extremizing cues like the Tea Party label can have a moderating effect on opponents. These findings shed new light on the role and interaction of party‐related voting cues, and have important implications for elections, campaigns, and voter opinion and behavior.
Understanding Attitudes Toward Nuclear Energy After the Fukushima Accident: Differences Between Asserted and Ambivalent Positions*
Authors: Crettaz von Roten F. , Clémence A. , Thevenet A. 
Published: July 2016

ObjectiveThe goal of this article is to understand the attitudes toward nuclear energy after the Fukushima accident. Such an analysis necessitates the avoidance of a dichotomous perspective (pro/against)—consider “supporter,” “neither‐nor,” and “opponent”—and to determine the effect of various factors on attitudes.MethodsThis study analyzes a 2013 Swiss survey that measures public attitudes toward nuclear energy.ResultsPublic acceptance of nuclear power remains lower two years after. Attitudinal structure of neither‐nor indicates ambivalence. Different factors explain the three positions.ConclusionsPublic attitudes toward nuclear energy are in line with Swiss energy strategy for 2050 to ban nuclear energy. These results draw practical implications for implementing political decisions and for policy communication.
European Neighbourhood Policy: History, Structure, and Implemented Policy Measures
Authors: Wesselink Edzard , Boschma Ron 
Published: July 2016

AbstractThe objective is to provide an overview of the European Neighbourhood Policy (ENP). Focus will be on the history of the ENP and its goals, the institutional structure of the ENP, and the policy measures that have been carried out through the ENP. The evolution of the ENP is traced from its origins in a 2003 European Commission communication to the broad and multifaceted policy that it is nowadays. Then the institutional dimension of the ENP, with both its thematic and spatial elements on a sub‐national, national, regional and interregional level will be explored. Finally, we present the specific policy measures that have been implemented on an interregional, regional, and national level.
Alveococcosis of the liver – strategy of surgical treatment with special focus on liver transplantation
Authors: Patkowski W. , Kotulski M. , Remiszewski P. , Grąt M. , Zieniewicz K. , Kobryń K. , Najnigier B. , Ziarkiewicz‐Wróblewska B. , Krawczyk M. 
Published: July 2016

AbstractBackgroundEchinococcosis is a zoonosis caused by infestation with any of 4 (of the 16) members of the Echinococcus genus, namely Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthus, and Echinococcus vogelii. The aim of this retrospective analysis was to present the outcomes of patients undergoing liver resection and liver transplantation (LT) for E. multilocularis infection.MethodsA total of 44 patients who underwent surgical treatment of E. multilocularis infection in the period between 1989 and 2014 were included in the study cohort and retrospectively analyzed.ResultsLT was performed in 22 patients (50.0%), including 4 of 26 patients undergoing initial non‐transplant management. Non‐transplant procedures comprised liver resection in 23 patients (88.5%), diagnostic laparoscopy in 2 (7.7%), and left adrenalectomy in 1 patient (3.8%). Post‐transplantation survival rates were 90%, 85%, and 75% at 1, 5, and 10 years, respectively.ConclusionIn conclusion, LT for E. multilocularis infection is a safe and effective treatment method.
Nucleos(t)ide analog(s) prophylaxis after hepatitis B immunoglobulin withdrawal against hepatitis B and D recurrence after liver transplantation
Authors: Cholongitas E. , Goulis I. , Antoniadis N. , Fouzas I. , Imvrios G. , Giakoustidis D. , Giouleme O. , Papanikolaou V. , Akriviadis E. , Vasiliadis T. 
Published: July 2016

AbstractBackground/aimsNucleos(t)ide analogs (NAs) have made a hepatitis B immunoglobulin (HBIG)‐sparing protocol an attractive approach against hepatitis B virus (HBV) recurrence after liver transplantation (LT). However, this approach is considered controversial in patients transplanted for HBV and hepatitis D (HDV) co‐infection.Material/MethodsAll patients transplanted for HBV/HDV cirrhosis were evaluated. After LT, each patient received HBIG + NAs and then continued with NAs prophylaxis. All patients were followed up with HBV serum markers and HBV DNA, while anti‐HDV/HDV RNA was performed in those with HBV recurrence.ResultsA total of 34 recipients were included (22 men, age: 46.7 ± 16 years). After HBIG discontinuation, NAs were received as monoprophylaxis (lamivudine [LAM]: 2, adefovir [AFV]: 1, entecavir: 9, tenofovir [TDF]: 12) or dual prophylaxis (LAM + AFV [or TDF]: 10 patients). Two (5.8%) of the 34 patients had HBV/HDV recurrence after HBIG withdrawal (median follow‐up: 28 [range, 12–58] months). These 2 patients had undetectable HBV DNA at LT. Statistical analysis revealed that those with recurrence had received HBIG for shorter period, compared to those without recurrence (median: 9 vs. 28 months, P = 0.008).ConclusionsWe showed for the first time, to our knowledge, that maintenance therapy with NAs prophylaxis after HBIG discontinuation was effective against HBV/HDV recurrence, but it seems that a longer period of HBIG administration might be needed before it is withdrawn after LT.
Draft Genome Sequences of Two
Aspergillus fumigatus
Strains, Isolated from the International Space Station
Authors: Singh Nitin Kumar , Blachowicz Adriana , Checinska Aleksandra , Wang Clay , Venkateswaran Kasthuri 
Published: July 2016

ABSTRACT

Draft genome sequences of
Aspergillus fumigatus
strains (ISSFT-021 and IF1SW-F4), opportunistic pathogens isolated from the International Space Station (ISS), were assembled to facilitate investigations of the nature of the virulence characteristics of the ISS strains to other clinical strains isolated on Earth.
Draft Genome Sequence of
Salmonella enterica
subsp.
enterica
Serovar Lille Strain CRJJGF_000101 (Phylum
Gammaproteobacteria
)
Authors: Gupta Sushim K. , McMillan Elizabeth A. , Jackson Charlene R. , Desai Prerak T. , Porwollik Steffen , McClelland Michael , Hiott Lari M. , Humayoun Shaheen B. , Frye Jonathan G. 
Published: July 2016

ABSTRACT

Here, we report a 4.98 Mbp draft genome sequence of
Salmonella enterica
subsp.
enterica
serovar Lille strain CRJJGF_000101, isolated from ground beef in 2007.
Draft Whole-Genome Sequence of the Type Strain
Bacillus horikoshii
DSM 8719
Authors: Hernández-González Ismael L. , Olmedo-Álvarez Gabriela 
Published: July 2016

ABSTRACT

Members of the
Bacillus
genus have been extensively studied because of their ability to produce enzymes with high biotechnological value. Here, we report the draft of the whole-genome sequence of the type strain
Bacillus horikoshii
DSM 8719, an alkali-tolerant strain.
Whole-Genome Sequence of
Escherichia coli
Serotype O157:H7 Strain EDL932 (ATCC 43894)
Authors: Uhlich Gaylen A. , Paoli George C. , Chen Chin-Yi , Cottrell Bryan J. , Zhang Xinmin , Yan Xianghe 
Published: July 2016

ABSTRACT

The genome sequence of
Escherichia coli
serotype O157:H7 EDL933, a ground beef isolate from a 1983 hemorrhagic colitis outbreak, is a standard reference for comparative genomic studies of Shiga toxin-producing
E. coli
strains. Here, we report the genome sequence of a patient stool isolate from that outbreak, strain EDL932.
Complete Genome Sequence of
Bacillus velezensis
CBMB205, a Phosphate-Solubilizing Bacterium Isolated from the Rhizoplane of Rice in the Republic of Korea
Authors: Hwangbo Kyeong , Um Yurry , Kim Ki Yoon , Madhaiyan Munusamy , Sa Tong Min , Lee Yi 
Published: July 2016

ABSTRACT

Bacillus velezensis
CBMB205 (= KACC 13105
T
= NCCB 100236
T
) was isolated from the rhizoplane of rice (
Oryza sativa
L. cv. O-dae). According to previous studies, this bacterium has several genes that can promote plant growth, such as the phosphorus-solubilizing protein-coding gene. Here, we present the first complete genome of
B. velezensis
CBMB205.
Complete Genome Sequence of
Sphingomonas
sp. Strain NIC1, an Efficient Nicotine-Degrading Bacterium
Authors: Zhu Xiongyu , Wang Weiwei , Xu Ping , Tang Hongzhi 
Published: July 2016

ABSTRACT

Sphingomonas
sp. strain NIC1, an efficient nicotine-degrading bacterium, was isolated from tobacco leaves. Here, we present the complete genome sequence of strain NIC1, which contains one circular chromosome and two circular plasmids. The genomic information will provide insights into its molecular mechanism for nicotine degradation.
Whole-Genome Sequence of
Filimonas lacunae,
a Bacterium of the Family
Chitinophagaceae
Characterized by Marked Colony Growth under a High-CO
2
Atmosphere
Authors: Shiratori-Takano Hatsumi , Takano Hideaki , Ueda Kenji 
Published: July 2016

ABSTRACT

We report here the genome sequence of
Filimonas lacunae
, a bacterium of the family
Chitinophagaceae
characterized by high-CO
2
-dependent growth. The 7.81-Mb circular genome harbors many genes involved in carbohydrate degradation and related genetic regulation, suggesting the role of the bacterium as a carbohydrate degrader in diverse environments.
Draft Genome Sequences of Four Bacterial Strains Isolated from a Polymicrobial Culture of Naked (N-Type)
Emiliania huxleyi
CCMP1516
Authors: Orata Fabini D. , Rosana Albert Remus R. , Xu Yue , Simkus Danielle N. , Bramucci Anna R. , Boucher Yan , Case Rebecca J. 
Published: July 2016

ABSTRACT

Strains of
Sulfitobacter
spp.,
Erythrobacter
sp., and
Marinobacter
sp. were isolated from a polymicrobial culture of the naked (N-type) haptophyte
Emiliania huxleyi
strain CCMP1516. The genomes encode genes for the production of phytohormones, vitamins, and the consumption of their hosts' metabolic by-products, suggesting symbiotic interactions within this polymicrobial culture.