bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mucosal Inducible NO Synthase–Producing IgA+ Plasma Cells in Helicobacter pylori–Infected Patients
Authors: Neumann Laura , Mueller Mattea , Moos Verena , Heller Frank , Meyer Thomas F. , Loddenkemper Christoph , Bojarski Christian , Fehlings Michael , Doerner Thomas , Allers Kristina , Aebischer Toni , Ignatius Ralf , Schneider Thomas 
Published: July 2016

Abstract
The mucosal immune system is relevant for homeostasis, immunity, and also pathological conditions in the gastrointestinal tract. Inducible NO synthase (iNOS)–dependent production of NO is one of the factors linked to both antimicrobial immunity and pathological conditions. Upregulation of iNOS has been observed in human Helicobacter pylori infection, but the cellular sources of iNOS are ill defined. Key differences in regulation of iNOS expression impair the translation from mouse models to human medicine. To characterize mucosal iNOS-producing leukocytes, biopsy specimens from H. pylori–infected patients, controls, and participants of a vaccination trial were analyzed by immunohistochemistry, along with flow cytometric analyses of lymphocytes for iNOS expression and activity. We newly identified mucosal IgA-producing plasma cells (PCs) as one major iNOS+ cell population in H. pylori–infected patients and confirmed intracellular NO production. Because we did not detect iNOS+ PCs in three distinct infectious diseases, this is not a general feature of mucosal PCs under conditions of infection. Furthermore, numbers of mucosal iNOS+ PCs were elevated in individuals who had cleared experimental H. pylori infection compared with those who had not. Thus, IgA+ PCs expressing iNOS are described for the first time, to our knowledge, in humans. iNOS+ PCs are induced in the course of human H. pylori infection, and their abundance seems to correlate with the clinical course of the infection.
Identification of Stage-Specific Surface Markers in Early B Cell Development Provides Novel Tools for Identification of Progenitor Populations
Authors: Jensen Christina T. , Lang Stefan , Somasundaram Rajesh , Soneji Shamit , Sigvardsson Mikael 
Published: July 2016

Abstract
Whereas the characterization of B lymphoid progenitors has been facilitated by the identification of lineage- and stage-specific surface markers, the continued identification of differentially expressed proteins increases our capacity to explore normal and malignant B cell development. To identify novel surface markers with stage-specific expression patterns, we explored the reactivity of CD19+ B cell progenitor cells to Abs targeted to 176 surface proteins. Markers with stage-specific expression were identified using a transgenic reporter gene system subdividing the B cell progenitors into four surface IgM− stages. This approach affirmed the utility of known stage-specific markers, as well as identifying additional proteins that selectively marked defined stages of B cell development. Among the stage-specific markers were the cell adhesion proteins CD49E, CD11A, and CD54 that are highly expressed selectively on the most immature progenitors. This work identifies a set of novel stage-specific surface markers that can be used as a complement to the classical staining protocols to explore B lymphocyte development.
Nummular headache: Clinico-epidemiological features in South Indian population
Authors: Rammohan K. , Mundayadan Shyma M. , Mathew Robert 
Published: July 2016

ABSTRACT
Context: Nummular headache (NH) is a primary disorder characterized by head pain exclusively felt in a small-rounded area typically 2–6 cm in diameter. Aims: The aim of this review is to study the clinical and epidemiological features of NH in a patient population of South India and to compare this with that of described in the international literature. Settings and Design: A prospective, observational study conducted in a tertiary care center. Materials and Methods: Patients attending the medicine and neurology outpatient departments of a tertiary referral hospital in South India diagnosed to have NH as per the International Classification of Headache Disorders 3 beta (2013) criteria were studied over 30 months. All of the patients had a normal neurological examination. Neuroimaging findings were normal, except in one patient. Results: A total of 19 females and 10 males were studied. The mean age of onset was 47.62 years (range 36–60). The duration of headache varied from a minimum of 3 months to a maximum of 5 years, with a mean of 24.17 months. The site of headache was predominantly in the parietal area 15 (51.72%), followed by the occipital area 7 (24.13%). The mean diameter of the affected area was 3.23 cm. The intensity of the headache proved to be mild to moderate with a mean visual analog scale score of 5.03. The quality of pain was mainly felt as burning dysesthesia 12 (41.38%). In the majority of patients, i.e. 21 (72.41%), pain was chronic and continuous. None of the patients had any significant trophic change even though paresthesias, dysesthesias, and allodynia were reported by a significant minority of patients, i.e. 9 (31.03%). Only one (3.45%) patient gave a history of head injury. Ten (34.48%) out of 29 patients had other types of concurrent headaches; the majority of which proved to be migrainous, i.e. 7 (24.14%), 2 patients (6.89%) with tension headache, and 1 patient (3.45%) with trigeminal neuralgia. Conclusion: Our study proves the existence of the newly described primary headache syndrome called NH in South Indian population. In comparing our results with the international literature, the number of similarities is much greater than the differences. The etiology of pain in our series appeared to be primarily peripheral with a role for central pain sensitization in some cases due to a variety of concurrent central causes of head pain.
Comparación de modelos de interceptación de agua de lluvia en individuos aislados de Pinus pinea y Cistus ladanifer
Authors: Pérez-Arellano R. , Moreno-Pérez M. F. , Roldán-Cañas J. 
Published: July 2016

<p>En este trabajo se realiza una comparación de varios modelos de simulación del proceso de interceptación, comúnmente utilizados en numerosos estudios, como son las versiones clásicas de Rutter y de Gash, además de la versión adaptada por Valente a bosques dispersos. El objetivo es analizar la aplicabilidad de los diferentes modelos en ejemplares aislados de dos especies de clima mediterráneo, Pinus pinea y Cistus ladanifer. La toma de datos se ha realizado en la cuenca de “El Cabril” (Córdoba), desde octubre de 2010 a junio de 2015. Las diferencias obtenidas entre las medidas de campo y los resultados de los diferentes modelos son inferiores al 6%, siendo el modelo de Rutter en su versión original el que mejor se ajusta en pino y el modelo original de Gash el que mejor se ajusta en el caso de la jara.</p>
Model-based aviation advice on distal volcanic ash clouds by
assimilating aircraft in situ measurements
Authors: Fu Guangliang , Heemink Arnold , Lu Sha , Segers Arjo , Weber Konradin , Lin Hai-Xiang 
Published: July 2016

Abstract. The forecast accuracy of distal volcanic ash clouds is important for providing valid aviation advice during volcanic ash eruption. However, because the distal part of volcanic ash plume is far from the volcano, the influence of eruption information on this part becomes rather indirect and uncertain, resulting in inaccurate volcanic ash forecasts in these distal areas. In our approach, we use real-life aircraft in situ observations, measured in the northwestern part of Germany during the 2010 Eyjafjallajökull eruption, in an ensemble-based data assimilation system combined with a volcanic ash transport model to investigate the potential improvement on the forecast accuracy with regard to the distal volcanic ash plume. We show that the error of the analyzed volcanic ash state can be significantly reduced through assimilating real-life in situ measurements. After a continuous assimilation, it is shown that the aviation advice for Germany, the Netherlands and Luxembourg can be significantly improved. We suggest that with suitable aircrafts measuring once per day across the distal volcanic ash plume, the description and prediction of volcanic ash clouds in these areas can be greatly improved.
Finite Element Approximation and Numerical Analysis of Three-dimensional Electrical Impedance Tomography
Authors: Yuan Yirang , Li Jiuping , Li Changfeng , Sun Tongjun 
Published: July 2016

Electrical impedance tomography is solved by solving an inverse problem of elliptic equation, and a new numerical method or a new technique is argued to consider finite element (such as normal element and mixed element) in this paper on three dimensional region. Introducing different perturbations to boundary restrictions and using different spacial steps, the authors obtain numerical solutions and give comparison with exact solutions. Numerical data show that numerical solution can approximate exact solution well as spacial step taken small and the approximation of Neumann boundary condition is more stable than that of Dirichlet case.<br />For Newton iterations on finite element method, a large-scaled system of massive linear equations is solved in each iteration, thus the computation is quite expensive. So two techniques are argued in the first half of this paper. Firstly, the invariance property of quasi-element stiffness matrix is used in the iterations and a type of special current model is introduced. Then the minimum number of direct problems solved is considered. Later a local conservative numerical approximation, low order mixed element (block-centered method) is presented in the latter part and the positive semi-definiteness and the existence of its solution are proved. Computational formula of error functional Jacobi matrix is derived and the least direct problems in each iteration are solved by using the symmetry of algorithm and a special current basis. This method has been applied successfully in actual numerical simulation of three-dimensional electrical impedance tomography.
Value8: over publieke figuren en principiële vragen
Authors: Koburg A.P. 
Published: July 2016

Value8: over publieke figuren en principiële vragen
Op 15 juni 2016 vond de jaarvergadering van Value8 N.V. plaats. Ruim een maand voorafgaande aan deze vergadering publiceerde Roel Gooskens een artikel op de website Follow The Money waarin hij zich kritisch uitlaat over de waardering van nog niet gerealiseerde waardestijgingen. Dat leidde tot veel reacties, die zijn in te delen in grofweg twee categorieën: (1) wat is de omvang van het recht op informatie van de algemene vergadering? (2) wat mag verwacht worden van grootaandeelhouder en bestuurder Peter Paul de Vries? De column besteedt kort aandacht aan beide aspecten.
Bonje binnen de vereniging van eigenaars
Authors: Kemp B. 
Published: July 2016

Bonje binnen de vereniging van eigenaars. Een bespreking van misbruik van meerderheidsmacht aan de hand van Rb. Limburg 5 november 2015, ECLI:NL:RBLIM:2015:9607
Handelt een appartementseigenaar in strijd met de redelijkheid en billijkheid als hij in lijn met zijn persoonlijke belang stemt? De kantonrechter oordeelde van wel. In de bijdrage wordt ingegaan op materieelrechtelijke en procesrechtelijke aspecten van besluitvorming en het aantasten van die besluitvorming binnen VvE’s.
Experiências das puérperas adolescentes no processo de parturição Experiences in the process of teenage pregnancy parturition
Authors: Escobal Ana Paula de Lima , Soares Marilu Correa , Meincke Sonia Maria Konzgen , Kerber Nalu Pereira da Costa , Santos Cristiano Pinto dos , Matos Greice Carvalho de 
Published: July 2016

Objetivo: Conhecer as experiências das puérperas adolescentes no processo de parturição. Método: De abordagem qualitativa e caráter descritivo, trata-se de um recorte dos dados da pesquisa multicêntrica Atenção Humanizada ao Parto de Adolescentes. Fizeram parte do estudo dez adolescentes que tiveram seus partos no hospital participante da pesquisa no período que compreendeu entre novembro de 2008 a novembro de 2009. As participantes foram selecionadas no banco de dados da pesquisa multicêntrica. Para análise, os dados foram agrupados em consonância com Minayo (2010). Resultados: Obtendo-se como resultado dois temas: percepções das puérperas sobre o cuidado recebido no centro obstétrico e os profissionais de saúde no processo de parturição. Conclusão: Constatou-se que as puérperas adolescentes que perceberem o comprometimento da equipe e julgarem que aquele cuidado fora o ideal, experimentaram o processo de parturição de mais forma prazerosa.
Toward the Geoscience Paper of the Future: Best practices for documenting and sharing research from data to software to provenance
Authors: Gil Yolanda , David Cédric H. , Demir Ibrahim , Essawy Bakinam T. , Fulweiler Robinson W. , Goodall Jonathan L. , Karlstrom Leif , Lee Huikyo , Mills Heath J. , Oh Ji‐Hyun , Pierce Suzanne A. , Pope Allen , Tzeng Mimi W. , Villamizar Sandra R. , Yu Xuan 
Published: July 2016

AbstractGeoscientists now live in a world rich with digital data and methods, and their computational research cannot be fully captured in traditional publications. The Geoscience Paper of the Future (GPF) presents an approach to fully document, share, and cite all their research products including data, software, and computational provenance. This article proposes best practices for GPF authors to make data, software, and methods openly accessible, citable, and well documented. The publication of digital objects empowers scientists to manage their research products as valuable scientific assets in an open and transparent way that enables broader access by other scientists, students, decision makers, and the public. Improving documentation and dissemination of research will accelerate the pace of scientific discovery by improving the ability of others to build upon published work.
Isotopic signature of extreme precipitation events in the western U.S. and associated phases of Arctic and tropical climate modes
Authors: McCabe‐Glynn Staryl , Johnson Kathleen R. , Strong Courtenay , Zou Yuhao , Yu Jin‐Yi , Sellars Scott , Welker Jeffrey M. 
Published: July 2016

AbstractExtreme precipitation events, commonly associated with “Atmospheric Rivers,” are projected to increase in frequency and severity in western North America; however, the intensity and landfall position are difficult to forecast accurately. As the isotopic signature of precipitation has been widely utilized as a tracer of the hydrologic cycle and could potentially provide information about key physical processes, we utilize both climate and precipitation isotope data to investigate these events in California from 2001 to 2011. Although individual events have extreme isotopic signatures linked to associated circulation anomalies, the composite across all events unexpectedly resembles the weighted mean for the entire study period, reflecting diverse moisture trajectories and associated teleconnection phases. We document that 90% of events reaching this location occurred during the negative Arctic Oscillation, suggesting a possible link with higher‐latitude warming. We also utilize precipitation data of extreme precipitation events across the entire western U.S. to investigate the relationships between key tropical and Arctic climate modes known to influence precipitation in this region. Results indicate that the wettest conditions occur when the negative Arctic Oscillation, negative Pacific/North American pattern, and positive Southern Oscillation are in sync and that precipitation has increased in the southwestern U.S. and decreased in the northwestern U.S. relative to this phase combination's 1979–2011 climatology. Furthermore, the type of El Niño–Southern Oscillation event, Central Pacific or Eastern Pacific, influences the occurrence, landfall location, and isotopic composition of precipitation.
A Walk Down the Lane Gives Wings to Your Brain. Restorative Benefits of Rest Breaks on Cognition and Self‐Control
Authors: Steinborn Michael B. , Huestegge Lynn 
Published: July 2016

SummaryWe investigated the effect of rest breaks on mental‐arithmetic performance, examining performance as a function of the factor rest, time‐on‐task, and demand. We asked the following questions: (i) Does rest (vs a continuous‐work condition) improve cognitive performance? (ii) Is active rest (taking a walk) better than passive rest (watching a video)? (iii) Do compensatory effects of rest increase with time‐at‐work? (iv) Are there differential effects of rest on automatic and controlled processes? (v) Are there differential effects of rest on performance speed versus variability? The results indicate that while rest is generally beneficial for performance, these benefits are similar for active and passive rest. The benefits increase with time‐on‐task and are larger for high (vs low) demand. Further, the effects on average response speed originated only partially from a reduction in the probability of attentional failure, as indicated by reaction‐time (ex‐Gaussian model) distributional and delta‐plot analysis.Copyright © 2016 John Wiley & Sons, Ltd.
Synthesis of Graphene Oxide by Oxidation of Graphite with Ferrate(VI) Compounds: Myth or Reality?
Authors: Sofer Zdeněk , Luxa Jan , Jankovský Ondřej , Sedmidubský David , Bystroň Tomáš , Pumera Martin 
Published: July 2016

AbstractIt is well established that graphene oxide can be prepared by the oxidation of graphite using permanganate or chlorate in an acidic environment. Recently, however, the synthesis of graphene oxide using potassium ferrate(VI) ions has been reported. Herein, we critically replicate and evaluate this new ferrate(VI) oxidation method. In addition, we test the use of potassium ferrate(VI) for the synthesis of graphene oxide under various experimental routes. The synthesized materials are analyzed by a number of analytical methods in order to confirm or disprove the possibility of synthesizing graphene oxide by the ferrate(VI) oxidation route. Our results confirm the unsuitability of using ferrate(VI) for the oxidation of graphite on graphene oxide because of its high instability in an acidic environment and low oxidation power in neutral and alkaline environments.
Renewable chemical feedstocks from peanut shell liquefaction: Preparation and characterization of liquefied products and residue
Authors: Zhang Qinqin , Zhang Guangyu , Han Dezhi , Wu Yumin 
Published: July 2016

ABSTRACTThe objective of this investigation is to liquefy peanut shell for the preparation of aromatic polyol‐rich products. The influences of reaction parameters are discussed. It is found that, compared to single‐solvent, the mixture of polyethylene glycol and glycerol as solvents shows higher liquefaction efficiency. And the maximum liquefaction yield of 98.7 wt % can be achieved when the sulfuric acid content, mass ratio between polyethylene glycerol, glycerol, and peanut shell powder, liquefaction temperature, and time are 17 wt % (relative to peanut shell), 8/2/1, 150 °C, and 2 h, respectively. Furthermore, the solubility test result indicates that the liquefied products are fully soluble in the water and polyol. Meanwhile, the properties of the peanut shell and liquefaction residue were analyzed by means of attenuated total reflectance‐Fourier transform infrared spectroscope, thermal gravity analysis, and scanning electron microscope. The polysaccharide is degraded by the cleaving of C–O bond, and the lignin is decomposed by leaving the dominant linkages including β‐O‐4, 4‐O‐5, and dibenzodioxocin units. The fibers in the peanut shell are broken, and the nondegraded components in the residue lost their network structure. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 44162.
Asymmetric Construction of Pyrrolidines Bearing a Trifluoromethylated Quaternary Stereogenic Center via CuI‐Catalyzed 1,3‐Dipolar Cycloaddition of Azomethine Ylides with β‐CF3‐β,β‐Disubstituted Nitroalkenes
Authors: Tang Li‐Wei , Zhao Bao‐Jing , Dai Li , Zhang Man , Zhou Zhi‐Ming 
Published: July 2016

AbstractA direct and convenient method has been developed for the synthesis of optically active pyrrolidines bearing a quaternary stereogenic center containing a CF3 group at the C‐3 position of the pyrrolidine ring. The synthesis system, CuI/Si‐FOXAP‐catalyzed exo‐selective 1,3‐dipolar cycloaddition of azomethine ylides with β‐CF3‐β,β‐disubstituted nitroalkenes, provides pyrrolidines with high diastereoselectivities (up to >98:2 d.r.) and excellent enantioselectivities (up to >99.9 ee) and performs well for a broad scope of substrates under mild conditions.
The stability and validity of automated vocal analysis in preverbal preschoolers with autism spectrum disorder
Authors: Woynaroski Tiffany , Oller D. Kimbrough , Keceli‐Kaysili Bahar , Xu Dongxin , Richards Jeffrey A. , Gilkerson Jill , Gray Sharmistha , Yoder Paul 
Published: July 2016

Theory and research suggest that vocal development predicts “useful speech” in preschoolers with autism spectrum disorder (ASD), but conventional methods for measurement of vocal development are costly and time consuming. This longitudinal correlational study examines the reliability and validity of several automated indices of vocalization development relative to an index derived from human coded, conventional communication samples in a sample of preverbal preschoolers with ASD. Automated indices of vocal development were derived using software that is presently “in development” and/or only available for research purposes and using commercially available Language ENvironment Analysis (LENA) software. Indices of vocal development that could be derived using the software available for research purposes: (a) were highly stable with a single day‐long audio recording, (b) predicted future spoken vocabulary to a degree that was nonsignificantly different from the index derived from conventional communication samples, and (c) continued to predict future spoken vocabulary even after controlling for concurrent vocabulary in our sample. The score derived from standard LENA software was similarly stable, but was not significantly correlated with future spoken vocabulary. Findings suggest that automated vocal analysis is a valid and reliable alternative to time intensive and expensive conventional communication samples for measurement of vocal development of preverbal preschoolers with ASD in research and clinical practice. Autism Res 2017, 10: 508–519. © 2016 International Society for Autism Research, Wiley Periodicals, Inc.
Attention deficit hyperactivity disorder symptoms, type of offending and recidivism in a prison population: The role of substance dependence
Authors: Román‐Ithier Jan C. , González Rafael A. , Vélez‐Pastrana María C. , González‐Tejera Gloria M. , Albizu‐García Carmen E. 
Published: July 2016

AbstractBackgroundIt is unclear whether adult offenders with a history of attention deficit hyperactivity disorder (ADHD) are more likely to re‐offend, and if so, in any specific offences.AimThis study aimed to examine correlates of childhood ADHD symptoms among prisoners.MethodsA randomly selected sample of 1179 participants from the adult sentenced population of Puerto Rico (USA) reported their history of violent and non‐violent offences, age of first arrest and re‐offending. Participants completed retrospective measures of ADHD and a diagnostic interview for substance use disorders.ResultsSelf‐reported ADHD was associated with age of first arrest, a number of violent and non‐violent offences and re‐offending. The association with any non‐violent offending was explained statistically by substance use disorders and other psychosocial covariates. ADHD was independently associated with being under 15 years of age at first arrest and with re‐offending.ConclusionsAlthough some associations between ADHD and offending may be accounted for by co‐morbidity with substance use disorders, early onset of offending and repeated violent offending appear to be directly related to ADHD. Criminal justice policies should, therefore, incorporate ADHD screening accompanied by appropriate rehabilitation programmes when such neurodevelopmental disorder is identified. Copyright © 2016 John Wiley & Sons, Ltd.