bluuebunny/crossref_metadata_2025_split huggingface dataset:
Behaviour and Psychopathology in Preschool Children with William Syndrome and the Effects of Age, Sex and Cognition
Authors: Miezah Daniel , Porter Melanie , Batchelor Jennifer , Rossi Adriana , Reeve Jessica 
Published: October 2024

AbstractThe current study compared the prevalence of cognitive and psychopathological impairments among 24 preschool children with Williams syndrome (WS) (aged 2.20 to 5.97 years) and 53 controls without WS and screened for developmental or psychological diagnoses (aged 2.21 to 5.89 years) matched on chronological age and sex distribution. Associations between sex, chronological age, early development and psychopathology were also investigated. The Child Behavior Checklist—Preschool Version (CBCL) and the Mullen Scales of Early Learning were administered. Higher reported rates of Attention Problems, Emotional Reactivity, Somatic Complaints, Withdrawal, Affective Problems and Total Problems were found in preschool children with WS. There were no significant group differences in prevalence rates of all other CBCL domains. Attention Problems were the most prevalent psychopathology in preschool children with WS (33% falling in the clinically significant range), followed by Affective Problems (29% in clinically significant range), then Anxiety Problems (17%) or Attention Deficit/Hyperactivity Problems (17%). Among children without WS, the highest prevalence rates of psychopathology were for Attention Problems (4% falling in the clinically significant range), Aggressive Behaviour (4%), Sleep Problems (4%) and Oppositional Defiant Problems (4%). There were no significant associations between sex or chronological age and CBCL-reported psychopathology for either group. In addition, there were no significant relationships between CBCL ratings and verbal ability, nonverbal ability or overall developmental level in either group. Findings highlight variations in the pattern of psychopathology among preschool children with WS compared to those without WS, which needs to be considered in clinical management and future research.
Granulomas in Common Variable Immunodeficiency Display Different Histopathological Features Compared to Other Granulomatous Diseases
Authors: van Stigt Astrid C. , von der Thüsen Jan H. , Mustafa Dana A. M. , van den Bosch Thierry P. P. , Lila Karishma A. , Vadgama Disha , van Hagen Martin , Dalm Virgil A. S. H. , Dik Willem. A. , IJspeert Hanna 
Published: October 2024

AbstractGranulomatous disease affects up to 20% of patients with Common Variable Immunodeficiency (CVID). Granulomas are comprised of highly activated immune cells, and emerge in response to antigenic triggers. In CVID granulomas however, the underlying pathophysiology is unclear and the specific trigger remains unknown. Granuloma formation in CVID is often compared to sarcoidosis, although clinical context and prognosis differ, suggesting a different pathogenesis. The aim of this study was to investigate if the cellular organization and proteomics of granulomas in CVID is different from other granulomatous diseases. Therefore, tissue slides from formaldehyde fixed paraffin embedded biopsies obtained from patients with CVID, sarcoidosis, tuberculosis and foreign-material induced pseudo-sarcoidosis were stained with hematoxylin and eosin and assessed for histopathological characteristics. Targeted spatial protein analysis was performed, and immune fluorescent multiplex assays were used to analyze the cellular organization. Histological analysis revealed that CVID granulomas were smaller, less circumscribed, with fewer multinucleated giant cells and minimal fibrosis compared to the other granulomatous diseases. Spatial protein analysis showed that granulomas in all diseases expressed CD68, CD11c, CD44, CD127, and PD-L1. However in CVID, reduced expression of the fibrosis-related protein fibronectin, but enrichment of CD163, CD3 and FAPα inside CVID granulomas was observed. Immunofluorescence analysis conformed a different cellular organization in CVID granulomas with increased influx of neutrophils, macrophages, T and B lymphocytes. In conclusion, granulomas in CVID display a different histological and cellular organization with increased influx of myeloid and lymphoid cells, compared to sarcoidosis, tuberculosis and pseudo-sarcoidosis, indicating a distinct pathogenesis underlying granuloma formation.
Delivering scientific evidence for global policy and management to ensure ocean sustainability
Authors: Evans K. , Schmidt J. O. , Addo K. Appeaning , Bebianno M. J. , Campbell D. , Fan J. , Gonzalez-Quiros R. , Mohammed E. Y. , Shojaei M. G. , Smolyanitsky V. , Zhang C.-I. 
Published: October 2024

Abstract
Life depends on the ocean, with societal health, cultural systems and national economies reliant on ocean processes and resources. As ocean resources are used, and humans continue to drive climate change, the benefits from the ocean to society are being diminished. Science must meet the needs of policy and deliver to decision makers the information and tools for identifying pathways that support continued delivery of the benefits society derives from the ocean, whilst minimising impacts. This is crucial if the world’s nations are to meet the goals and targets they have set under international agreements. Here, we outline how a global assessment that focuses specifically on the ocean, the World Ocean Assessment, is linking science to the governments of the world and their policies within an internationally mandated framework. In doing so, we identify key elements that are needed for facilitating engagement by decision makers and uptake of knowledge, and the pathways taken by the assessment in implementing them. We also provide insights into the evolution that the World Ocean Assessment has undertaken over its first three cycles to progress its goal of enhancing the scientific basis of policymaking. We identify the challenges in delivering science to policy at a global scale and the work that still needs to be done in filling gaps to achieve a coordinated, comprehensive mechanism for connecting science with policy and ensuring future sustainability of the ocean.
Investigation of Protective Coatings for Reducing High-Temperature Oxidation of Steels
Authors: Mugale Manoj , Choudhari Amit , Karki Sanoj , Desai Jay , Walunj Ganesh , Vukkum Venkata B. , Schwam David , Gupta Rajeev Kumar , Borkar Tushar 
Published: October 2024

Abstract
Oxidation of steel billets during pre-heating at elevated temperatures is a challenge, particularly in the forging industry. There is a need to address this problem by applying effective oxidation-resistant coatings on forging billets. In this investigation, different types of commercially available high-temperature, oxidation-resistant coatings, termed Coating A, B, C, D, E, F, and G, were applied on AISI 4340 low-alloy steel by spraying and dipping at room temperature. The oxidation protection behavior of each coating was studied over a wide range of temperatures and holding times in atmospheric conditions. The weight and height losses caused by oxidation were measured, and the samples were subsequently characterized using XRD and SEM-EDS. The protection mechanisms and anti-oxidation properties of the coatings are discussed in detail. The sample coated with Coating A showed the best protection at all temperatures compared to other coatings. The weight/height loss of Coating A-coated steel samples was reduced by 80–90% compared to an uncoated/bare sample. Coating A not only limited the outward diffusion of iron cations from the substrate but also prevented the inward diffusion of oxygen anions from the atmosphere, resulting in better oxidation resistance. The findings of the study should apply to other steels with similar compositions.
When the Nose Meets the Lab: Histopathological Analysis in Chronic Rhinosinusitis with Nasal Polyps for Routine Clinical Practice
Authors: Alobid Isam , Armengot-Carceller Miguel , Pinilla Urraca Mayte , Maza-Solano Juan , González Guijarro Isabel , Umbria Jiménez Sebastián , San Miguel Fraile Pilar , Mullol Joaquim 
Published: October 2024

Abstract
Purpose of review
We aimed to review the latest evidence regarding the value of tissue histopathological analysis in chronic rhinosinusitis with nasal polyps (CRSwNP) and to facilitate tissue analysis by proposing a pragmatic checklist for clinical settings.

Recent findings
CRSwNP is a chronic inflammatory disease that severely impairs the patient’s quality of life. The severity of the disease can be correlated with nasal polyps enriched in eosinophils/IL-5 and, although ≥ 10 eosinophils per high power field are considered enough to determine an eosinophilic CRS, this cut-off value, the biopsy method, and the sampling location are still a matter of debate. Besides, tissue eosinophil values might also have some added value when combined with other cellular counts (e.g., eosinophil-to-lymphocyte ratio, Charcot-Leyden crystals). Structured histopathology analysis of sinonasal tissue—including, for instance, tissue remodelling biomarkers, fibrosis, and eosinophilic aggregates—has proven to be a valuable tool for healthcare professionals to identify different pheno-endotypes of CRSwNP and to improve the prioritisation of candidates to targeted therapies. Patients with CRSwNP are treated according to their severity with corticosteroids (intranasal and systemic), endoscopic sinus surgery, and/or biological therapy.

Summary
A panel of expert ear, nose, and throat specialists and pathologists proposed a pragmatic checklist to improve the clinical practice around tissue analysis in CRSwNP, to facilitate communication between hospital-based healthcare professionals, and to standardize the evaluation of inflammatory biomarkers.
Nuanced synthesis strategies and comprehensive analysis of intricate multifarious luminescent phosphor hosts
Authors: Kiran R. , Prabhu Nimitha S. , Mishra Vikash , Sayyed M. I. , Kamath Sudha D. 
Published: October 2024

AbstractThis paper primarily addresses various methodologies for synthesizing novel phosphors, with our focus mainly on the mixed alkaline tungstate phosphor Ca2MgWO6. In the initial synthesis phase, we used precisely weighed CaCO3, MgO, and WO3 for the synthesis. The XRD patterns indicated the presence of an impure phase, specifically CaWO4, in the resulting product. We adeptly tackled the formation of CaWO4 and mitigated it by employing a multifaceted approach. These included adding an excess amount of MgO, opting for an alternative chemical route, and the incorporation of flux during synthesis. It was observed that the product obtained through the addition of flux exhibited a purity level of approximately 99.75% with a margin of error of ± 0.02%. Ultimately, we have carried out structural, morphological, optical, and thermal characterizations, along with density functional theory (DFT) simulations, to assess the fundamental parameters of the pure sample.
Scaffolding Fifth Graders’ Learning with a Digital Multi-Representation Applet: Design Research on Focusing Multiplicative Structures with Dynamic Dot Arrays
Authors: Abraham Malina , Prediger Susanne 
Published: October 2024

AbstractDigital multi-representation applets offer promising opportunities for promoting students’ conceptual understanding by dynamically converting graphical and symbolic representations and for promoting discoveries and justifications of mathematical properties. However, learning effects of open-ended multi-representation applets seem to depend on targeted scaffolds for students’ processes of conversions, treatments, and conversions of treatments. While these design challenges have come to be well-understood for dynamic geometry and functions, more design research is needed for multi-representation applets for multiplicative reasoning. We report on a design research study in Grade 5 in which the multi-representation applet of a dynamic dot array was integrated into a digital teaching–learning environment with sequenced tasks and more targeted scaffolds. The qualitative analysis of 30 students’ processes revealed multiple potentials of the dynamic array to (a) connect static representations by articulating the underlying multiplicative unit structures (conversions), (b) describe systematic variations (coordinated treatments), (c) explain systematic variations in representations by articulating unit structures (conversions of variations), (d) discover multiplicative commutativity (treatments), and (e) go towards justifying multiplicative commutativity by restructuring the array and its unit structures (conversions of treatments). Design experiment Cycle 1 revealed that all potentials were partially addressed by some students. To enable students to exploit more of these multiple potentials, attention scaffolds and language scaffolds were integrated. In Cycle 2, more potentials were exploited while still leaving room for improvements. In total, the study shows how design research can contribute to embed multi-representation applets into teaching–learning environments with well-sequenced tasks and targeted scaffolds.
Progress Toward Biocarbon Utilization in Electric Arc Furnace Steelmaking: Current Status and Future Prospects
Authors: DiGiovanni Christopher , Echterhof Thomas 
Published: October 2024

AbstractSteel is an essential material in modern infrastructure and industry, but its production is associated with significant carbon dioxide emissions. Biocarbon utilization in electric arc furnace (EAF) steelmaking represents a promising pathway toward reducing the carbon footprint of steel production. This review draws new perspectives on the current state of biocarbon utilization in EAF steelmaking by collectively examining the literature from multiple scales of testing, from laboratory experiments to industrial trials. The scientific insights from each scale are defined and the results are collectively pooled to give a comprehensive understanding of biocarbon’s performance for EAF applications. Several recent progressions are identified along with critical limitations, such as biocarbon’s high reactivity or low density. However, solution pathways like agglomeration are established from the thorough understanding developed by this study. These insights aim to enhance the progression of biocarbon utilization in the EAF process, ultimately facilitating the development of more efficient and sustainable steelmaking. The proposed areas for future research, such as optimizing key biocarbon properties or improved injection systems, are expected to have significant impact on the next phase of biocarbon adoption.
Graphical Abstract
Implementation of an autonomous mobile platform for agricultural tasks in corridor-like environments
Authors: Tobias Jonathan , Lim Shen Hin , Duke Mike , McGuinness Benjamin , Au Chi Kit 
Published: October 2024

AbstractThe role of autonomous vehicles (AVs) in assisting people is recognised and, therefore, is in constant development in numerous fields. Specifically, the ability of an autonomous vehicle (AV) to alleviate global stressors, such as the increased potential for food shortages and the decline in available workers for labor-intensive tasks. An area where the development of AVs are particularly prevalent is in agriculture. However, the few AVs being used in agriculture are often custom-built for specific purposes and require long development time as a result. This article aims to build and evaluate a versatile architecture for a mobile platform that is implemented using off-the-shelf components so that it can be transferred to any agricultural vehicle, thus reducing the development time. The research has involved investigating and incorporating various sensors, and also developing a common software module to perform the localisation, navigation and mapping particularly suited for corridor crop agricultural environments. This architecture has been integrated and implemented on a Yamaha golf cart, integrating it with sensors and electronics to allow a Robotic Operating System (ROS) framework to gather information and control the vehicle. As the architecture is modular in nature, it can be transferred to different customised platforms. To determine the efficacy of the mobile platform, it has undergone evaluation in simulation and in the field. The evaluation demonstrates that both mapping and navigation have satisfactory results, and the mobile platform remains within 5 mm of the specified distance when aiming to follow the row in a vineyard. The results from these experiments demonstrate the ability of the mobile platform to successfully transform a Yamaha golf cart into an autonomous agricultural vehicle.
Gone-wild grapevines in forests host phytoplasma genotypes linked to grapevine’s flavescence dorée epidemics in cultivated vineyards and competent vectors
Authors: Oggier Alan , Conedera Marco , Debonneville Christophe , Schumpp Olivier , Rizzoli Attilio 
Published: October 2024

Abstract“Flavescence dorée” (FD) is a quarantine grapevine disease associated with FD phytoplasmas (FDp). In Switzerland, FD was identified in 2004 in the southernmost part of Canton Ticino (TI) and then rapidly propagated throughout the entire regional winegrowing area despite the mandatory control measures. The reported widespread distribution of gone-wild grapevines (GWGV) in TI raised the hypothesis of a potential role of GWGV as an FDp reservoir and as a habitat for FDp vectors. To test this assumption, GWGV and FDp vectors were sampled in 13 plots to attest their infection status and compare the FDp genetic profiles. The primary (Scaphoideus titanus) and best-candidate alternative (Orientus ishidae) vectors were collected throughout the season and were found in moderate to high abundance in all the study area. The infection rate of both GWGV and S. titanus followed the historical gradient of S. titanus arrival and dispersal in TI with a clear geographic distinction between the southern and northern part of TI. Interestingly, the rate measured for S. titanus was similar to that observed in highly FD-infested cultivated vineyards. Moreover, the genetic profiles of the infected GWGV and S. titanus samples were identical to those commonly observed in cultivated vineyards (map M54). Importantly, four specimens of O. ishidae were also found harboring the same genotype. This study emphasizes the importance of GWGV (and abandoned vineyards) and alternative vectors for the FD epidemics in FD-infested regions, as well as a potential origin for FD outbreaks in areas currently designated as FDp-free.
Exploring the ripple effect: learner psycho-social challenges, teacher emotional fatigue, and the role of school social work in South Africa—an interview-based qualitative study using Bronfenbrenner's framework
Authors: Joubert C. , Jacobs Susanne 
Published: October 2024

AbstractGuided by Bronfenbrenner's (1994) ecological systems theory Bronfenbrenner (Int Encycl Educ,3(2):37–43) , this study highlights the interplay between learner psycho-social challenges and teacher emotional fatigue, which affect classroom dynamics, and the critical role of systemic support—the role of school social workers (SSWs)—in South Africa. Using an exploratory-descriptive qualitative design, we conducted semi-structured interviews with 15 primary school teachers and 13 SSWs from various provinces. Our participants' diverse backgrounds and experiences provided comprehensive insights. Findings highlight the need for a holistic approach to addressing learner psycho-social challenges, emphasising comprehensive support systems for teachers, including training and early intervention. Additionally, the integration of full-time SSWs and the active involvement of psychologists, families, and communities is crucial. Insights can inform educational policies and practices, enhancing teachers' and learners' well-being and effectiveness.
Digital finance infrastructure and growth of commercial banking firms in Nigeria
Authors: Iwedi Marshal 
Published: October 2024

AbstractThis study delves into the intricate relationship between digital finance infrastructure and the growth of commercial banking firms in Nigeria. Through a comprehensive analysis of various financial indicators and statistical tests, we offer critical insights into the dynamics of the Nigerian banking sector. The findings reveal a resilient and steadily growing banking industry, even in the face of economic challenges and the global COVID-19 pandemic. Key highlights include the exponential rise in digital infrastructure, exemplified by the proliferation of Automated Teller Machines (ATMs), Point of Sale (POS) machines, and web banking accounts. These digital channels have significantly influenced the accessibility and convenience of banking services in Nigeria. Our analysis employs correlation, regression, and Granger causality tests to explore the intricate relationships between bank total assets and digital infrastructure components. While positive correlations between bank total assets and digital infrastructure components suggest a strong link between technological expansion and banking growth, the analysis reveals nuanced relationships. Furthermore, while web banking accounts have grown significantly, their influence on bank total assets remains limited. Our findings emphasize the paramount importance of continued investments in digital finance infrastructure for the Nigerian banking sector's growth. However, they also underscore the need for a more profound understanding of the underlying drivers of these trends. This study offers valuable insights for policymakers, financial institutions, and researchers interested in fostering financial inclusion and optimizing digital banking services in Nigeria's ever-evolving financial landscape. In conclusion, this study highlights the critical role of digital finance infrastructure in driving the growth of commercial banking firms in Nigeria, while also calling for more targeted strategies to maximize the benefits of technological advancements in the banking sector.
Perspectives and awareness of environmental sustainability in the infection prevention and control community nationally
Authors: Pearl Abarna , Pepe Dana E. , Mehrotra Preeti 
Published: October 2024

Abstract
In this survey of infection prevention and control (IPC) professionals, we gauged knowledge, attitudes and institutional practices related to environmental sustainability and IPC. Overall, IPC professionals have not yet universally adopted measures to promote environmental sustainability. More research is needed around environmentally sustainable efforts that preserve patient safety in IPC.