bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bridging the Gap in Adult Dyslexia Research: Assessing the Efficacy of a Linguistic Intervention on Literacy Skills
Authors: Vender Maria , Delfitto Denis 
Published: September 2024

AbstractWhile developmental dyslexia has been extensively studied in children, research on adults is still rather limited. This paper aims to bridge the gap in existing research by presenting the findings of a study that examined the reading and spelling skills of adults with dyslexia and assessed the effectiveness of a linguistic intervention designed to improve their literacy abilities. To address this issue, we first compared the profiles of 44 adults with dyslexia (age range: 16–30 y.o.) and 44 age-matched typical readers across tasks assessing reading, spelling, phonological awareness, morphological awareness and lexical access in Italian. The findings underscored pervasive impairments in dyslexia across all measured dimensions, reaffirming the persistent nature of language and literacy challenges into adulthood. In pursuit of the second objective, the study explored the potential for literacy skill improvement in adults with dyslexia through the implementation of a specialized intervention proposed to 24 dyslexic adults and delivered via a web application. The intervention program yielded positive outcomes in the experimental group, demonstrating significant improvements in word and text reading, spelling, and speed of phonological elaboration. This study, hence, contributes not only to our understanding of developmental dyslexia in adulthood but also emphasizes the tangible benefits of targeted linguistic interventions, thereby offering practical implications for the amelioration of literacy skills in this population.
Essential Reads in Rhinology: A Bibliometric Analysis
Authors: Shaari Ariana L. , Bhalla Shreya , Ho Rebecca , Dupaguntla Anup , Zabielski Sylvia , Hsueh Wayne , Eloy Jean Anderson , Filimonov Andrey 
Published: September 2024

Abstract
Aims
Rhinology is a progressive subspecialty within otolaryngology. Bibliometric analysis is a powerful method to survey the landscape of literature on a specific topic and identify publication trends. We aimed to analyze the 50 most impactful English-language rhinology manuscripts of all time to create a targeted reading list for otolaryngologists.

Material and Methods
The Journal Citation Report within the Web of Science database was utilized to identify articles relating to rhinology. Web of Science Research categories were restricted to otolaryngology. The articles were then ranked by number of citations. The top 50 articles of all time ranked by number of citations were analyzed. The articles were analyzed for publication year, journal impact factor, citation density, first author (FA), and senior author (SA) name, country, and institution. Statistical analyses were performed.

Results
Most articles were published in the 2000s (N = 22, 44%) and 1990s (N = 11, 22%). Male FA (N = 37, 74%) and SA (N = 43, 86%) published most articles. Most articles were clinical studies (N = 36, 72%) followed by clinical guidelines/expert opinions. Most articles were published in the United States (N = 28, 56%) and England (N = 9, 18%). There were more female FAs of guidelines/position papers than basic lab, reviews, and clinical studies. England had more female FAs than other countries, and the United States had more female SA. There was an average of 585.2 citations per study.

Conclusion
This investigation highlights the most influential literature within rhinology. The most impactful studies are consensus statements, large multicenter studies, and technique studies. Significant gender disparities in authorship exist.
Valorization of Waste Wool to Keratin with a Green Solvent Based on a Deep Eutectic Mixture of Choline Chloride and Lactic Acid
Authors: Pääkkönen Iiris , Rissanen Tiina , Ora Ari , Anugwom Ikenna 
Published: September 2024

Abstract
Waste wool, a by-product of sheep husbandry, is primarily composed of keratin, which has potential use in cosmetic products, biotechnology and medical applications. Traditional chemical methods for keratin extraction face limitations due to health and environmental concerns, and thus, green alternatives such as deep eutectic solvents (DESs) have been developed. The aim of the present study was to determine whether a natural DES composed of choline chloride and lactic acid can be used to extract keratin from sheep wool. The dissolution and keratin yield were investigated under different reaction times, temperatures, and wool-to-DES ratios. Fractions of water-soluble keratin and water-insoluble keratin aggregates were obtained by dialysis, centrifugation, and drying. The results showed that both the dissolution of wool and the yield of recovered keratin increased as the reaction time and temperature increased from 1 to 8 h and from 80 to 110 $$^{\circ }$$

∘

C, respectively. With the longest reaction time of 8 hours and the highest temperature of 110 $$^{\circ }$$

∘

C, the yield of water-soluble keratin increased to 23 %. Characterizations revealed that DES detached first the cuticular scales from the surface of wool fibres and subsequently degraded wool cortex layer. The extracted water-soluble keratin retained the characteristic amide structure of wool, but the secondary structure of keratin was converted to cross-$$\beta$$
β
sheet form. Moreover, it had a narrow size distribution and a molecular weight of 10 kDa. The results of this study indicate that the proposed DES can be used as a green solvent for recovering keratin from sheep wool.

Graphical Abstract
Enhancing IoT connectivity through spectrum sharing in 5G networks
Authors: Singh Bablu Kumar , Khatri Narendra 
Published: September 2024

AbstractThe integration of the Internet of Things (IoT) into high-performance devices and monitoring systems, spanning domains such as smart building, e-health care, and smart agriculture, necessitates a critical emphasis on advancing mobile communications through efficient spectrum utilization. This research addresses pivotal challenges within agricultural IoT applications, specifically focusing on the substantial decline in spectrum efficiency observed with the increasing escalation of network bandwidth. Acknowledging the absence of comprehensive reviews on 5G resource allocation strategies in the existing literature, our study aims to contribute to a nuanced understanding of their implications for service quality. The identified research gaps underscore an urgent need for heightened efforts to optimize resource allocation in 5G networks. This investigation delves into the intricacies of spectrum sharing and real-time analysis techniques within the 5G and beyond network, with a targeted focus on augmenting agricultural IoT services. Three distinct models, namely (i) Non-Priority Algorithm (NPA), (ii) Reserved Channel Algorithm (RCA) - No Permanent Channels, and (iii) Reserved Channel Algorithm (RCA) - Permanent Channels, were meticulously designed and simulated for Agricultural IoT application scenarios. The methodology encompasses the comprehensive evaluation of performance metrics, including call blocking, termination, and handover, to strategically identify and allocate spectrum resources effectively. The research endeavors to address ongoing challenges pertaining to effective communication, standardization, and data management for diverse 5G IoT devices. In light of these persisting concerns, the study not only seeks to enhance the overall efficiency of 5G IoT networks but also proposes innovative perspectives on intelligent and ingenious spectrum allocation techniques. The anticipated outcomes pledge to optimize the utilization of limited spectrum through novel spectrum-sharing strategies, thereby contributing to the advancement of 5G networks and bolstering agricultural IoT devices and services.
Wireless Ultrasound Devices in Anatomy Education: Insights from Medical Undergraduates
Authors: de Lange Johanna Maria , Baatjes Karin J. , Marthinussen Chad , Correia Janine C. 
Published: September 2024

AbstractPoint-of-care ultrasound has become an important part of patient care, and the increased use thereof has led to a greater demand for the integration of ultrasound training in the early medical undergraduate curriculum. The use of handheld wireless ultrasound devices is not currently integrated within the undergraduate anatomy medical curriculum of Stellenbosch University and the additional value of wireless ultrasonography, in relation to the clinical practice of anatomical knowledge, therefore, warranted further investigation. This study aimed to explore undergraduate medical students’ perceptions of the use of handheld wireless ultrasound scanning to enhance knowledge and understanding of anatomy for clinical application. During the dissection sessions, students visualized anatomical structures of the musculoskeletal system, by scanning themselves, using handheld, wireless ultrasound devices. After the session, an electronic survey was distributed to the students and three ultrasonography questions were included in the routine practical test. Eighty-one survey responses were collected, with 41 of those responses being completed. The highest student agreement in the Likert scale survey was observed when assessing the convenience of practice of wireless ultrasound devices, while the lowest agreement was reported for confidence in the participant’s capability of generating ultrasound images. Two main themes were developed from the open-ended questions at the end of the survey: the instructional integration of ultrasound and ultrasound within the clinical setting. This research demonstrated that readily available access to handheld wireless ultrasound scanning has the potential to enhance students’ longitudinal learning experience and improve anatomical comprehension. As future clinicians, improved understanding could aid ultrasound application in the clinical realm.
HoLens: A visual analytics design for higher-order movement modeling and visualization
Authors: Feng Zezheng , Zhu Fang , Wang Hongjun , Hao Jianing , Yang Shuang-Hua , Zeng Wei , Qu Huamin 
Published: September 2024

AbstractHigher-order patterns reveal sequential multistep state transitions, which are usually superior to origin-destination analyses that depict only firstorder geospatial movement patterns. Conventional methods for higher-order movement modeling first construct a directed acyclic graph (DAG) of movements and then extract higher-order patterns from the DAG. However, DAG-based methods rely heavily on identifying movement keypoints, which are challenging for sparse movements and fail to consider the temporal variants critical for movements in urban environments. To overcome these limitations, we propose HoLens, a novel approach for modeling and visualizing higher-order movement patterns in the context of an urban environment. HoLens mainly makes twofold contributions: First, we designed an auto-adaptive movement aggregation algorithm that self-organizes movements hierarchically by considering spatial proximity, contextual information, and temporal variability. Second, we developed an interactive visual analytics interface comprising well-established visualization techniques, including the H-Flow for visualizing the higher-order patterns on the map and the higher-order state sequence chart for representing the higher-order state transitions. Two real-world case studies demonstrate that the method can adaptively aggregate data and exhibit the process of exploring higher-order patterns using HoLens. We also demonstrate the feasibility, usability, and effectiveness of our approach through expert interviews with three domain experts.
„Im Judentum besteht die Bibel nur aus dem Alten Testament“. Konstruktionen des Verhältnisses Christentum–Judentum in Schulbüchern für die Fächer katholische und evangelische Religion sowie Werte und Normen
Authors: Chiriac Christine , Sadowski Dirk 
Published: September 2024

Zusammenfassung
Vor dem Hintergrund einer kritischen Auseinandersetzung mit dem Forschungsstand in der Bildungsmedienforschung untersucht dieser Beitrag Darstellungen des Judentums in Schulbüchern der Sekundarstufe I für den katholischen und evangelischen Religions- sowie den Werte-und-Normen-Unterricht in Niedersachsen. Genauer behandelt der Beitrag die Frage, wie das Verhältnis von Christentum (bzw. einer christlich geprägten, säkularen Kultur) und Judentum in den Schulbüchern konstruiert wird. Er zeigt, wie diese Relation nicht (mehr) dichotom gezeichnet wird, sondern in vielfältiger Weise ‚unscharf‘ bleibt.
Impact of tele-antimicrobial stewardship at two small community hospitals in partnership with an academic medical center: two years of experience
Authors: Ross Jennifer K. , Chandorkar Aditya A. 
Published: September 2024

Abstract

Objective:
To analyze the impact of a fully remote tele-antimicrobial stewardship program (TASP) at two small community hospitals in partnership with an academic medical center.

Design:
Retrospective survey from August 1, 2020, to July 31, 2022.

Setting:
A TASP, co-led by an infectious diseases (ID) physician and ID pharmacist, was implemented at M Health Fairview (MHF) Northland, a 21-bed hospital, and at MHF Lakes, a 49-bed hospital. The ID physician and ID pharmacist are located at the University of Minnesota Medical Center.

Methods:
Antimicrobial stewardship interventions were tracked monthly. Restricted antimicrobial days of therapy per 1000 patient days (DOT/1000 PD) were also tracked monthly and two years pre and postimplementation data were compared. All annual antimicrobial expenditures were followed.

Results:
For the first two TASP years, a total of 789 antimicrobial interventions were made with 85.6% being accepted. Restricted antimicrobial use trended down from 142.93 to 113.97 DOT/1000 PD at MHF Northland. A smaller decrease from 106.31 to 103.12 DOT/1000 PD was seen at MHF Lakes. Annual antimicrobial costs per total patient days decreased. MHF Northland hospital’s annual antimicrobial expenditures per total patient days fell from $18.89 in 2019 (preimplementation) to $6.64. MHF Lakes followed a similar trend, decreasing from $11.20 to $5.36.

Conclusions:
A fully remote TASP in partnership with an academic medical center for two small community hospitals resulted in high rates of accepted interventions sustained over two years. Restricted antimicrobial use and antimicrobial costs trended down.
Mortality in hospitalized SARS-CoV-2 patients with contemporaneous bacterial and fungal infections
Authors: Hanna John J. , Most Zachary M. , Cooper Lauren N. , Wakene Abdi D. , Radunsky Alexander P. , Lehmann Christoph U. , Perl Trish M. , Medford Richard J. 
Published: September 2024

AbstractBackground:The interplay between SARS-CoV-2 and contemporaneous bacterial or fungal culture growth may have crucial implications for clinical outcomes of hospitalized patients. This study aimed to quantify the effect of microbiological culture positivity on mortality among hospitalized patients with SARS-CoV-2.Methods:In this retrospective cohort study, we included adult hospitalized patients from OPTUM COVID-19 specific data set, who tested positive for SARS-CoV-2 within 14 days of hospitalization between 01/20/2020 and 01/20/2022. We examined outcomes of individuals with organisms growing on cultures from the bloodstream infections (BSIs), urinary tract, and respiratory tract, and a composite of the three sites. We used propensity score matching on covariates included demographics, comorbidities, and hospitalization clinical parameters. In a sensitivity analysis, we included same covariates but excluded critical care variables such as length of stay, intensive care unit stays, mechanical ventilation, and extracorporeal membrane oxygenation.Results:The cohort included 104,560 SARS-CoV-2 positive adult hospitalized patients across the United States. The unadjusted mortality odds increased significantly with BSIs (98.7%) and with growth on respiratory cultures (RC) (176.6%), but not with growth on urinary cultures (UC). Adjusted analyses showed that BSIs and positive RC independently contribute to mortality, even after accounting for critical care variables.Conclusions:In SARS-CoV-2-positive hospitalized patients, positive bacterial and fungal microbiological cultures, especially BSIs and RC, are associated with an increased risk of mortality even after accounting for critical care variables associated with disease severity. These findings underscore the importance of stringent infection control and the effective management of secondary infections to improve patient outcomes.
Leveraging oncology collaborative networks and biomedical informatics data resources to rapidly recruit and enroll rural residents into oncology quality of life clinical trials
Authors: Davis Heath A. , Hoberg Asher A. , Jacobus Laura S. , Nepple Kenneth , Seaman Aaron T. , Sorensen Jamie , Weiner George J. , Gilbertson-White Stephanie 
Published: September 2024

Abstract

Purpose:
This study assesses the feasibility of biomedical informatics resources for efficient recruitment of rural residents with cancer to a clinical trial of a quality-of-life (QOL) mobile app. These resources have the potential to reduce costly, time-consuming, in-person recruitment methods.

Methods:
A cohort was identified from the electronic health record data repository and cross-referenced with patients who consented to additional research contact. Rural–urban commuting area codes were computed to identify rurality. Potential participants were emailed study details, screening questions, and an e-consent link via REDCap. Consented individuals received baseline questionnaires automatically. A sample minimum of n = 80 [n = 40 care as usual (CAU) n = 40 mobile app intervention] was needed.

Results:
N = 1298 potential participants (n = 365 CAU; n = 833 intervention) were screened for eligibility. For CAU, 68 consented, 67 completed baseline questionnaires, and 54 completed follow-up questionnaires. For intervention, 100 consented, 97 completed baseline questionnaires, and 58 completed follow-up questionnaires. The CAU/intervention reached 82.5%/122.5% of the enrollment target within 2 days. Recruitment and retention rates were 15.3% and 57.5%, respectively. The mean age was 59.5 ± 13.5 years. The sample was 65% women, 20% racial/ethnic minority, and 35% resided in rural areas.

Conclusion:
These results demonstrate that biomedical informatics resources can be highly effective in recruiting for cancer QOL research. Precisely identifying individuals likely to meet inclusion criteria who previously indicated interest in research participation expedited recruitment. Participants completed the consent and baseline questionnaires with zero follow-up contacts from the research team. This low-touch, repeatable process may be highly effective for multisite clinical trials research seeking to include rural residents.
Developmental human resource practices, thriving at work, and employee agility: The moderating role of workplace spirituality
Authors: Yang Chengchuan , Tang Chunyong , Xu Nan , Lai Yanzhao 
Published: September 2024

Abstract
Grounded in self-determination theory, this study unveils the connection between developmental human resource (HR) practices and employee agility by examining employees’ workplace spirituality and thriving at work. Based on data collected from 428 employees, our empirical analysis has demonstrated that the relationship between developmental HR practices and employee agility is partially mediated by thriving at work. The results also indicate that employees’ workplace spirituality moderates the relationship among developmental HR practices, thriving at work, and employee agility. These findings have unveiled the underlying mechanism of the link between developmental HR practices and employee agility. This research offers fresh insights into the studies on employee agility and provides potential HR management recommendations for enhancing organizational agility in corporate strategic planning.
Nutritional status and its associated factors among infants and young children aged 6–23 months in Addis Ababa, Central Ethiopia, 2021: a cross-sectional study
Authors: Hailu Sisay , Jara Dube , Bogale Eyob Ketema 
Published: September 2024

Abstract
The aim of this study is to assess nutritional status and associated factors among infants and young children aged 6–23 months in Yeka sub-city, Ethiopia, 2021. An institution-based cross-sectional study was conducted in selected health centres found in the Yeka sub-city from May 2021 to July 2021. In total, 396 systematically selected infants and young children aged 6–23 months attended the selected health centres were included in the study. Data were collected by using a structured questionnaire and anthropometric measurements. A multinomial logistic regression model was used.
The overall magnitude of undernutrition and overnutrition among infants and young children were 24.7% and 5.5%, respectively. Dietary diversity score (DDS) ((adjusted odd ratio (AOR) = 5.65; 95% CI = 2.301, 10.87; P value = 0.003), minimum meal frequency (MMF) (AOR = 5.435; 95% CI = 2.097, 11.09; P value = 0.0052), and diarrhoea (AOR = 2.52; 95% CI = 1.007, 6.310; P value = 0.002) were statistically significantly associated factors for nutritional status among infants and young children. Malnutrition (undernutrition and overnutrition) is a public health problem among infants and young children in Yeka sub-city, Ethiopia. DDS, MMF, and diarrhoeal disease were associated with higher odds of undernutrition.
Relationship between coronary artery disease with dyslipidaemia and trace mineral intake: a cross-sectional analysis of the Shika study
Authors: Kimura Kei , Suzuki Fumihiko , Tsujiguchi Hiromasa , Hara Akinori , Miyagi Sakae , Kannon Takayuki , Suzuki Keita , Shimizu Yukari , Nguyen Thao Thi Thu , Katano Koji , Asai Atsushi , Kasahara Tomoko , Nakamura Masaharu , Takazawa Chie , Hayashi Koichiro , Hamagishi Toshio , Shibata Aki , Sato Takehiro , Nomura Akihiro , Konoshita Tadashi , Kambayashi Yasuhiro , Tsuboi Hirohito , Tajima Atsushi , Kobayashi Takayuki , Nakamura Hiroyuki 
Published: September 2024

Abstract
Although the relationship between dyslipidaemia (DL) and coronary artery disease (CAD) or between trace minerals intake and CAD is well known separately, the exact nature of this relationship remains unknown. We hypothesize that the relationship between trace mineral intake and CAD may differ depending on whether or not the individual has DL. The present study analysed the relationships among trace mineral intake, DL, and CAD in middle-aged and older adults living in Shika town, Ishikawa prefecture, Japan. This study included 895 residents following the exclusion of those with genetic risk carriers for familial hypercholesterolemia. Trace mineral intake was evaluated using the brief-type self-administered diet history questionnaire. Interactions were observed between DL and CAD with zinc (p = 0.004), copper (p = 0.010), and manganese intake (p < 0.001) in a two-way analysis of covariance adjusted for covariates such as sex, age, body mass index, and current smokers and drinkers. Multiple logistic regression analysis showed that zinc (odds ratio (OR): 0.752; 95% confidence interval (CI): 0.606, 0.934; p = 0.010), copper (OR: 0.175; 95% CI: 0.042, 0.726; p = 0.016), and manganese (OR: 0.494; 95% CI: 0.291, 0.839; p = 0.009) were significant independent variables for CAD in the dyslipidaemic group. The present results suggest that DL with a low trace mineral intake is associated with CAD. Further longitudinal studies are required to confirm this relationship.