bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Survey of Management of Congenital Nasolacrimal Duct Obstruction by Pediatric Primary Health Care Providers in Spain
Authors: Galindo-Ferreiro Alicia , Palencia-Ercilla Teresa , Ferreira Livia Mendoza , Galvez-Ruiz Alberto , Zornoff Denise C.M. , Khandekar Rajiv , Schellini Silvana A. 
Published: December 2016

Purpose To survey the management of congenital nasolacrimal duct obstruction (CNLDO) by pediatric primary health care providers in Spain. Methods This was a descriptive study using a web-based questionnaire to evaluate the perceptions of the members of the Pediatric Primary Care Society in Castilla-León, Spain (APAPCYL), regarding management of CNLDO. The questionnaire contained 14 direct questions and was sent by e-mail to all the pediatricians. All the responses were analyzed by the frequency of occurrence and percentages. Results Ninety physicians responded to the questionnaire. Massage 2 or 3 times a day was the initial treatment advised by 60.47% of pediatricians. Nearly half of the pediatricians recommended continuing massage until symptoms resolved. Fewer than 50% of children required referral to an ophthalmologist. Reasons for an ophthalmic consult included persistence of symptoms among 87.21% of pediatricians and parental/guardian request among 10.5% of pediatricians. According to 45.6% of pediatricians, their knowledge about CNLDO is limited, and 92.2% would like to receive further training on CNLDO. Conclusions Massage was the main initial treatment for managing CNLDO among pediatricians. The outcomes of this survey indicated that massage fails in fewer than 50% of patients and an ophthalmic referral is required for these cases.
Clinical Outcomes of Ceramicized Ball Heads in Total Hip Replacement Bearings: A Literature Review
Authors: Piconi Corrado , De Santis Vincenzo , Maccauro Giulio 
Published: December 2016

Background Metallic ball heads for total hip replacement (THR) bearings with ceramicized surfaces were introduced in orthopedics during the second half of the 1980s, with the aim of decreasing the wear of polyethylene cups. Methods An analysis was made of the literature regarding outcomes for metallic ball heads with ceramicized surfaces now in clinical use (TiN, TiNbN, ZrN, monoclinic ZrO2), as well as carbon coatings (pyrolytic carbon, diamond-like carbon) and silicon nitride as coatings in ball heads for THR bearings. Results Notwithstanding the diffusion of ceramicized ball heads in THRs, there are few reports about their clinical outcomes in hip arthroplasty. In addition, several clinical studies and some registry data are putting under scrutiny the clinical advantages of ceramicized ball heads over cobalt chrome (CoCr) alloy and ceramic ball heads. Conclusions The wear of THR bearings with ceramicized ball heads looks like it depends more on the behavior of the polyethylene cups than on the treatment of the ball head surface. The risk of coating damage and of its consequences has to be taken into account in selecting this type of bearing.
Gene Polymorphisms of TLR2 and TLR3 in HBV Clearance and HBV-Related Hepatocellular Carcinoma in a Chinese Male Population
Authors: Chen Dongni , Xie Weimin , Lu Yongkui , Su Shining , Nong Li , Jia Yuxian , Liu Yan , Zhou Wenxian , Wang Hongxue , Tan Aihua 
Published: December 2016

Background The Toll-like receptor plays an essential role in controlling immunity and inflammation. This study was to investigate the relationships of genetic variants in TLR2 and TLR3 with hepatitis B virus (HBV) natural clearance and HBV-related hepatocellular carcinoma (HCC) risk in a Chinese male population. Methods We analyzed 5 polymorphisms of TLR2 (rs3804099 and rs3804100) and TLR3 (rs5743305, rs3775296 and rs3775291) in a population consisting of 686 participants with HBV natural clearance, 293 chronic HBV carriers and 395 HBV-positive HCC patients, using the improved multiplex ligase detection reaction method. Results After adjustment for age and smoking and drinking status, no associations were observed either between the 5 single-nucleotide polymorphisms (SNPs) and the HBV natural clearance participants, or between the 5 SNPs and HCC patients. Whereas the stratified analysis showed that under the dominant models, nondrinkers with TLR2 rs3804100 and participants younger than 40 years old with TLR3 rs3775291 were significantly associated with HCC risk when compared with persistent HBV carriers (adjusted odd ratio [OR] = 0.49, 95% confidence interval [95% CI], 0.31-0.78, p = 0.003; and adjusted OR = 0.50, 95% CI, 0.29-0.86, p = 0.013, respectively). Furthermore, the TTTCT haplotype was found to promote the progress of HBV clearance and inhibit development of HBV-related HCC (OR = 0.77, 95% CI, 0.61-0.97, p = 0.029; and OR = 0.72, 95% CI, 0.55-0.94, p = 0.016, respectively). And the CCACC and CCTCT haplotypes were observed to decrease susceptibility to HCC (OR = 0.64, 95% CI, 0.40-1.00, p = 0.048; and OR = 0.43, 95% CI, 0.28-0.68, p<0.001, respectively). Conclusions This study revealed that TLR2 rs3804100 and TLR3 rs3775291 polymorphisms may be protective factors for HBV-related HCC.
First Italian Consensus Conference on VATS Lobectomy for NSCLC
Authors: Nosotti Mario , Droghetti Andrea , Luzzi Luca , Solli Piergiorgio , Crisci Roberto ,   On behalf of the Italian VATS Group
Published: December 2016

Purpose Video-assisted thoracoscopic surgery (VATS) lobectomy has become an accepted procedure for the treatment of selected cases of lung cancer. The aim of this project was to establish national practical recommendations for the management of patients suitable for VATS lobectomy. Methods The Scientific Committee of the VATS Lobectomy Group (a branch of the Italian Society of Thoracic Surgery) identified the consensus conference as an appropriate tool for a national debate. The consensus conference was organized following indications of the Italian Department of Health: a panel of experts reviewed the literature, the jury board revised the experts’ reports, and the national conference discussed and voted on statements. The strength of recommendation for a statement was classified as weak, fair, or high when the total score ranged between 51% and 67%, 68% and 84%, or 85% and 100%, respectively. Results Eighty-six Italian thoracic surgeons attended the 1st Italian Consensus Conference on VATS lobectomy in Giulianova, Italy, on October 29-30, 2015. Thirty-three topics were discussed: indications, surgical strategy, perioperative management, and training were the main topics. Consensus was reached on 24 statements that were consequently recommended. Conclusions The Italian Consensus Conference is the first attempt to discuss VATS lobectomy-related issues in a national scientific community. Such experience determined an improvement in epistemic knowledge among the Italian thoracic surgeons and could be a suggestion for other national communities.
High-dose chemotherapy and peripheral hematopoietic stem cell transplantation in relapsed/refractory Hodgkin’s lymphoma
Authors: Kelta Mouhammed , Zekri Jamal , Abdelghany Ehab , Rehman Jalil Ur , Khan Zahid Amin , Al-Saadi Rawan , Dada Reyad 
Published: December 2016

Purpose: High-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT) is used to treat patients with relapsed Hodgkin’s lymphoma. In this retrospective study we report our experience with patients who underwent HDCT and ASCT. Methods: All patients ≥15 years old with relapsed/refractory Hodgkin’s lymphoma who underwent HDCT and ASCT between June 2001 and December 2013 were included. Results: Fifty-four patients were identified. Median age at transplant was 22 years (range 15-49 years); 26 were men and 28 were women. Forty-eight patients (89%) underwent HDCT and ASCT after achieving a radiological response to salvage chemotherapy. The rate of radiological complete response to salvage chemotherapy was 13% and reached 50% within 3 months of ASCT in assessable patients. After a median follow-up of 25 months, 31 patients (57%) were still alive with no evidence of relapse or progression. Median event-free survival (EFS) was 24 months (95% CI 8.7-39.3) and 3-year EFS was 56%. Median overall survival (OS) was not reached and 3-year OS was 82.5%. Bulky mediastinal disease at relapse, hemoglobin level, and number of salvage regimens did not significantly impact EFS in univariate and multivariate analyses. After transplantation there was a trend towards longer EFS (30 vs. 24 months; p = 0.36) in patients with a longer time from the end of first-line treatment until relapse (≥12 vs. <12 months). The 100-day transplant-related mortality was 5.5%. Conclusions: HDCT and ASCT for relapsed/refractory Hodgkin’s lymphoma is safe. Our findings are consistent with published phase III results. Longer follow-up is warranted.
As práticas discursivas do Banco Mundial: Políticas educacionais na América Latina e no Caribe. The discursive practices of the World Bank: Educational policies in Latin America and the Caribbean.
Authors: Silva Andréa Villela Mafra da 
Published: December 2016

Resumo Neste trabalho, utiliza-se como referencial teórico e metodológico a Análise Crítica do Discurso formulada por Norman Fairclough para caracterizar as práticas discursivas nas quais a publicação mais recente do Banco Mundial se inscreve. Trata-se do livro Professores Excelentes: Como melhorar a aprendizagem dos estudantes na América Latina e no Caribe de autoria de Barbara Bruns, Javier Luque e outros colaboradores. Esta publicação trata do desempenho dos professores da educação básica na América Latina e no Caribe, e como decorrência, busca compartilhar as políticas de formação docente que estão sendo implementadas nesses locais. A conclusão da pesquisa é que os baixos padrões para o ingresso no magistério têm produzido resultados inexpressivos na educação.AbstractIn this work, it is used as theoretical and methodological reference the Critical Discourse Analysis formulated by Norman Fairclough to characterize the discursive practices in which the most recent World Bank publication falls. This is the book Great Teachers: How to improve student learning in Latin America and the Caribbean authored by Barbara Bruns, Javier Luque and other employees. This publication addresses the basic education teacher performance in Latin America and the Caribbean, and as a result, search share the teacher training policies being implemented at these sites. The conclusion of the research is that low standards for entry into teaching have produced unimpressive results in education.
Docentes resilientes em contextos precários: Estudo de casos em Espanha
Authors: Sousa Carolina Silva , Extremera Marta Olmo 
Published: December 2016

O artigo debruça-se sobre docentes que enfrentam grandes desafios, em contextos socioeconómicos e culturais muito precários, em que os alunos apresentam muitas diferenças quanto às suas necessidades e aspirações educativas. Os docentes destas escolas acabam por atuar numa perspetiva mais social e moral do que académica e as famílias dos alunos demonstram pouca participação e interesse, junto às instituições de ensino nas quais os seus filhos estudam. A resiliência desempenha um papel importante ao ser entendida como uma atitude de resposta à adversidade com que os docentes se confrontam. A investigação centra-se, assim, no conceito e em alguns fatores a ele associados, como a busca do sucesso dos alunos e o bom funcionamento da escola. Neste enquadramento, as respostas obtidas com a recolha de dados são únicos para cada contexto social e educacional e seria errado extrapola-las, a partir de um centro para outro, porque cada centro tem a sua própria realidade. Os dados obtidos foram extraídos através do programa estatístico qualitativo Nvivo, tendo sido realizada uma análise da variável resiliência para se conhecer, de forma substantiva, o conteúdo que a define, assim como se identificam os fatores que têm sido mais e menos usados pelos participantes, atendendo às características próprias de cada instituição escolar. A análise de dados possibilitou conhecer como a resiliencia é interpretada pelos docentes e inventariar que fatores de resiliência estão mais presentes (ou não) nas práticas docentes dos informantes e a sua relação com as escolas em que lecionam. Por último, é de sublinhar que a percentagem de docentes cujo grau de compromisso contribui para o melhoramento escolar e social dos seus alunos é elevada, implicando-se no apoio e no trabalho em equipa, ante as dificuldades com as quais se confrontam, num esforço continuado de fazer das suas escolas um lugar de êxito.
Sollen et altérité selon Fichte
Authors: Dumont Augustin 
Published: December 2016

L’objectif de cet article est d’analyser la mobilisation fichtéenne du concept de Sollen en montrant de quelle manière ce dernier permet à Fichte de lier la dimension catégorique du savoir transcendantal à sa dimension problématique. L’article propose un parallèle entre la mobilisation du Sollen au plan de la fondation du savoir et sa mobilisation au plan de la théorie de l’intersubjectivité. Pour ce faire, l’article superpose trois points de vue : le point de vue fondamental de l’intersubjectivité pure, le point de vue appliqué de l’intersubjectivité juridique et le point de vue appliqué de l’intersubjectivité éthique.
L’argument de la Simulation et le problème de la classe de référence : le point de vue du contextualisme dialectique
Authors: Franceschi Paul 
Published: December 2016

Je présente dans cet article une analyse de l’argument de la Simulation selon le point de vue du contextualisme dialectique, fondée sur le problème de la classe de référence. Je décris tout d’abord l’argument de la Simulation de manière détaillée. J’identifie ensuite la classe de référence et j’applique successivement l’argument à trois classes de référence distinctes : les simulations conscientes de leur propre nature de simulation, les simulations imparfaites et les simulations à immersion. Finalement, je montre qu’il existe trois niveaux de conclusion dans l’argument de la Simulation, selon la classe de référence choisie, qui engendrent des conclusions finales d’une nature très différente.
Ces morts qui ne sont jamais oubliés : retour et survivance dans les séries télévisées contemporaines
Authors: Desmet Maud 
Published: December 2016

Parmi les différentes figures récurrentes représentant la mort dans les fictions télévisées s’en trouve une particulièrement troublante, celle d’un mort qui refuse de mourir totalement : le revenant. Si cette figure est peut-êtrelafigure de la mise en scène de la mort sur le petit écran, c’est justement parce qu’elle partage avec le médium sériel des qualités persistantes qui repoussent et nient constammentla fin. Banalité du médium et banalité de la figure se rejoignent également : le revenant est en effet la figure de « mort qui revient » la plus détachée de toute altérité. Il n’est ni le zombie ni le spectre, seulement un mort qui refuse la disparition physique, et dont le statut formel est similaire à celui des vivants. Cette mise en scène spécifique de la mort dans laquelle s’inscrit le revenant, parce qu’elle rend possible une réunion fictionnelle des morts et des vivants, interroge sans doute avec le plus de justesse et en rendant compte de toute sa complexité, notre relation réelle aux morts.
La forme du monumental : usage et circulation dans les représentations des morts dus à la Seconde Guerre mondiale
Authors: Trouche Dominique 
Published: December 2016

L’article analyse l’hypothèse d’une transformation par circulation de la forme du monumental plutôt que sa disparition à partir d’un corpus de monuments aux morts et mémoriaux érigés à partir de la Seconde Guerre mondiale. Si le monumental est associé à la grandeur, à la solidité, à l’imposant, nous montrons qu’à partir de la seconde moitié du XXe siècle, ces caractéristiques sont toujours présentes bien qu’ayant été profondément transformées. Sont ainsi identifiés quatre aspects qui oeuvrent, souvent conjointement, à une nouvelle matérialisation, par la représentation, des morts collectives dues aux guerres : le passage de la verticalité à l’horizontalité, l’irruption de fractures venant briser la masse monumentale, la fausse disparition du monumental par son enfermement sous terre et, enfin, la projection imagée du monumental.
Récit de vie et vécu de précarité sociale : exemple d’une recherche en psychologie soutenue par un logiciel de données qualitatives
Authors: Fierdepied Sophie , Sturm Gesine , Baubet Thierry 
Published: December 2016

Nous proposons d’exposer la dimension méthodologique
d’une recherche qualitative en psychologie, auprès
d’individus pris dans un processus de précarisation et,
dans ce cadre, l’apport d’un logiciel de traitement de
données qualitatives.
Il s’agit, dans cet article, de décrire et
d’argumenter les choix méthodologiques : ils
intègrent une démarche conceptualisante dans la tradition
de la théorie ancrée, une lecture
phénoménologique ainsi que l’utilisation
d’une lecture clinique. La réalisation des entretiens de
recherche est largement influencée par un outil
multimodèle et multiaxial, l’OPD-2 (Operationalized
Psychodynamic Diagnosis-2). Cette démarche méthodologique
peut ainsi être qualifiée de triangulation dans le sens
où elle intègre plusieurs perspectives théoriques
(psychanalytique, philosophique ou encore sociologique) et
méthodologiques (théorie ancrée,
phénoménologie, utilisation de l’OPD-2).
L’utilisation d’un logiciel de traitement de données
qualitatives a permis de faciliter cette démarche
méthodologique complexe. Il s’agit d’un logiciel qui
permet d’organiser les données, mais qui facilite aussi la
création de catégories conceptualisantes : ces
dernières sont rédigées par le chercheur à
partir d’une démarche de comparaison et de confrontation
des données à des idées, des
références théoriques grâce notamment
à l’écriture de mémos. Cette démarche
est la base des premières tentatives de théorisation du
chercheur : les résultats de la recherche sont
exposés succinctement à la fin de ce texte.
Après avoir décrit les différents
éléments de la méthodologie,
l’intérêt et les limites du logiciel NVivo dans
cette démarche seront discutés.
Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia
Authors: Cauci Sabina , Chiriacò Giovanni , Cecchin Erika , Toffoli Giuseppe , Xodo Serena , Stinco Giuseppe , Trombetta Carlo 
Published: December 2016

AbstractIntroductionLong-term adverse symptoms of men who used oral finasteride against androgenic alopecia have been recently described as post-finasteride syndrome (PFS).AimTo determine whether (CAG)n-rs4045402 and (GGN)n-rs3138869 polymorphisms in the androgen receptor (AR) gene are implicated in PFS.MethodsAR polymorphisms were studied according to PFS symptoms in 66 white participants (31.8% Italian, 28.8% American, and 39.4% other).Main Outcome MeasuresSymptoms were investigated by an ad hoc 100-item questionnaire and the Arizona Sexual Experience Scale and Aging Male Symptom Scale (AMS). (CAG)n and (GGN)n repeats were categorized as short ([CAG]9–19, [GGN]&lt;23), medium ([CAG]20–24, [GGN]23), or long ([CAG]25–37, [GGN]&gt;23).ResultsMedian age was 32 years, duration of finasteride use was 360 days, and time from finasteride discontinuation was 1,053 days. We observed several frequency differences in symptoms according to (CAG)n and (GGN)n repeat numbers. Three AMS items were worse for medium (GGN)23 than for long (GGN)&gt;23 carriers and one item was worse for short (GGN)&lt;23 carriers. The AMS item for decrease in sexual desire or libido was worse for short (CAG)9–19 carriers than for medium (CAG)20–24 carriers. Through the ad hoc questionnaire, significant findings in (CAG)n and/or (GGN)n repeats were obtained for penile discomfort, loss of scrotal sensitivity, scrotal discomfort, less pubic hair, loss of perceived perineal fullness, increased sperm density, involuntary muscle spasms, loss of muscle tone, increased weight (&gt;2 kg), increased skin dryness, and onset of symptoms after finasteride use.ConclusionThis study showed that short and/or long (CAG)n and (GGN)n repeats had different frequencies according to symptoms reported by patients with PFS, likely reflecting the vast array of genes modulated by the AR. This study showed a U-curvilinear profile of (CAG)n repeats for skin dryness symptoms, where the two extremes exhibited a worse condition than medium repeats. Further studies are necessary to investigate the PFS pathophysiology using a precision medicine approach.
In-hospital mortality among electroconvulsive therapy recipients: A 17-year nationwide population-based retrospective study
Authors: Liang C.-S. , Chung C.-H. , Tsai C.-K. , Chien W.-C. 
Published: December 2016

AbstractBackgroundElectroconvulsive therapy (ECT) remains irreplaceable in the treatment of several psychiatric conditions. However, evidence derived using data from a national database to support its safety is limited. The aim of this study was to investigate in-hospital mortality among patients with psychiatric conditions treated with and without ECT.MethodsUsing data from the Taiwan National Health Insurance Research Database from 1997 to 2013, we identified 828,899 inpatients with psychiatric conditions, among whom 0.19% (n = 1571) were treated with ECT.ResultsWe found that ECT recipients were more frequently women, were younger and physically healthier, lived in more urbanized areas, were treated in medical centers, and had longer hospital stays. ECT recipients had lower odds of in-hospital mortality than did those who did not receive ECT. Moreover, no factor was identified as being able to predict mortality in patients who underwent ECT. Among all patients, ECT was not associated with in-hospital mortality after controlling for potential confounders.ConclusionECT was indicated to be safe and did not increase the odds of in-hospital mortality. However, ECT appeared to be administered only on physically healthy but psychiatrically compromised patients, a pattern that is in opposition with the scientific evidence supporting its safety. Moreover, our data suggest that ECT is still used as a treatment of last resort in the era of modern psychiatry.