bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teaching the Passive Through Semantically Enhanced Input
Authors: Little Andrea , Fieldsend Terry 
Published: March 2017

This article reports on a small, classroom‐based study exploring the use of a task to teach the passive in an English for specific purposes context. The participants were 34 adult Japanese male learners, all security professionals, ranging in proficiency level from elementary to advanced. The task was designed to highlight the form–meaning connection by creating a need for learners to use the passive, and then introducing a focus on form as the students became aware of the gap in their current interlanguage resources. The task input consisted of a miniature apartment and a set of photos that had been semantically enhanced to elicit passives. Piloting the task with three native speakers (NS) confirmed the input was sufficient to induce a naturalistic use of passives. The data indicate the task was effective for increasing the use of the passive across a range of proficiencies both after the focus‐on‐form phase and in the posttask phase.
Development of an aeroelastic code based on three‐dimensional viscous–inviscid method for wind turbine computations
Authors: Sessarego Matias , Ramos‐García Néstor , Sørensen Jens Nørkær , Shen Wen Zhong 
Published: March 2017

AbstractAerodynamic and structural dynamic performance analysis of modern wind turbines are routinely estimated in the wind energy field using computational tools known as aeroelastic codes. Most aeroelastic codes use the blade element momentum (BEM) technique to model the rotor aerodynamics and a modal, multi‐body or the finite‐element approach to model the turbine structural dynamics. The present work describes the development of a novel aeroelastic code that combines a three‐dimensional viscous–inviscid interactive method, method for interactive rotor aerodynamic simulations (MIRAS), with the structural dynamics model used in the aeroelastic code FLEX5. The new code, called MIRAS‐FLEX, is an improvement on standard aeroelastic codes because it uses a more advanced aerodynamic model than BEM. With the new aeroelastic code, more physical aerodynamic predictions than BEM can be obtained as BEM uses empirical relations, such as tip loss corrections, to determine the flow around a rotor. Although more costly than BEM, a small cluster is sufficient to run MIRAS‐FLEX in a fast and easy way. MIRAS‐FLEX is compared against the widely used FLEX5 and FAST, as well as the participant codes from the Offshore Code Comparison Collaboration Project. Simulation tests consist of steady wind inflow conditions with different combinations of yaw error, wind shear, tower shadow and turbine‐elastic modeling. Turbulent inflow created by using a Mann box is also considered. MIRAS‐FLEX results, such as blade tip deflections and root‐bending moments, are generally in good agreement with the other codes. Copyright © 2017 John Wiley & Sons, Ltd.
Entropies, Partitionings and Heart Rate Variability
Authors: Palus Milan , Zebrowski Jan J. 
Published: March 2017

Abstract
Several definitions of static entropies and coarse-grained entropy rates (CER’s) were used to analyze 24-hour RR interval sequences of three sex, age and disease matched control pairs. The matching was done with the assessment of the risk of cardiac arrest in mind. Details of estimating probability densities (histograms), used to compute the static entropies, have been found crucial to obtain the proper discrimination between the members of control pairs. The effect of signal variance on the entropy estimation is discussed. In a preliminary result, CER’s have been found to yield additional information which may be helpful in discriminating health and pathology.
On the Antecedents of Palmar Hyperhidrosis
Authors: Kerassidis Stelios 
Published: March 2017

Abstract
In the context of the research on the antecedents of palmar hyperhidrosis, we compared hyperhidrotic in palm and normal individuals on parameters that could be related to excessive sweating. We performed neurological examination, general hematological tests, and measurements of blood levels of thyroid hormones FT3, FT4, TSH, glucose, and electrolytes Na, K, P, Ca, Mg. The participants also filled in the Eysenck Personality, as well as a laboratory constructed Questionnaire. Significantly more hyperhidrotic than normal individuals had a close relative suffering from palmar hyperhidrosis. In addition, hyperhidrotics scored significantly higher in Neuroticism scale of Eysenck Personality Questionnaire. No indi-cation of neurological damage, dysautonomy, hematological abnormality, electrolytic or glucose imbalance, and thyroid gland dysfunction was found for hyperhidrotics. The findings of the present work as well as the ones of previous works suggest that palmar hyperhidrosis cannot be attributed to pathological or anatomical features, it is possibly caused by personality traits, while a genetic predisposition may also contribute.
Mutations in SLC25A22: hyperprolinaemia, vacuolated fibroblasts and presentation with developmental delay
Authors: Reid Emma S. , Williams Hywel , Anderson Glenn , Benatti Malika , Chong Kling , James Chela , Ocaka Louise ,   GOSgene, Hemingway Cheryl , Little Daniel , Brown Richard , Parker Alasdair , Holden Simon , Footitt Emma , Rahman Shamima , Gissen Paul , Mills Philippa B. , Clayton Peter T. 
Published: March 2017

AbstractMutations in SLC25A22 are known to cause neonatal epileptic encephalopathy and migrating partial seizures in infancy. Using whole exome sequencing we identified four novel SLC25A22 mutations in six children from three families. Five patients presented clinical features similar to those in the literature including hypotonia, refractory neonatal‐onset seizures and developmental delay. However, the sixth patients presented atypically with isolated developmental delay, developing late‐onset (absence) seizures only at 7 years of age. Abnormal metabolite levels have not been documented in the nine patients described previously. One patient in our series was referred to the metabolic clinic because of persistent hyperprolinaemia and another three had raised plasma proline when tested. Analysis of the post‐prandial plasma amino acid response in one patient showed abnormally high concentrations of several amino acids. This suggested that, in the fed state, when amino acids are the preferred fuel for the liver, trans‐deamination of amino acids requires transportation of glutamate into liver mitochondria by SLC25A22 for deamination by glutamate dehydrogenase; SLC25A22 is an important mitochondrial glutamate transporter in liver as well as in brain. Electron microscopy of patient fibroblasts demonstrated widespread vacuolation containing neutral and phospho‐lipids as demonstrated by Oil Red O and Sudan Black tinctorial staining; this might be explained by impaired activity of the proline/pyrroline‐5‐carboxylate (P5C) shuttle if SLC25A22 transports pyrroline‐5‐carboxylate/glutamate‐γ‐semialdehyde as well as glutamate.
Attitudes Towards Prenatal Genetic Counseling, Prenatal Genetic Testing, and Termination of Pregnancy among Southeast and East Asian Women in the United States
Authors: Tsai Ginger J. , Cameron Carrie A. , Czerwinski Jennifer L. , Mendez‐Figueroa Hector , Peterson Susan K. , Noblin Sarah Jane 
Published: March 2017

AbstractRecognizing the heterogeneity of the Asian population with regards to acculturation, education, health awareness, and cultural values is vital for tailoring culturally sensitive and appropriate care. Prior studies show that cultural values influence perceptions of genetics within Asian populations. The reputation of the family unit factors into decisions such as pregnancy termination and disclosure of family medical history, and the nondirective model of American genetic counseling may conflict with the historical Asian model of paternalistic health care. Previous studies also provide conflicting evidence regarding correlations between education, acculturation, age, and awareness and perceptions of genetic testing. The aims of this study were to describe attitudes towards prenatal genetics among Southeast and East Asian women living in the United States for varying amounts of time and to explore sociocultural factors influencing those attitudes. Twenty‐three Asian women who were members of Asian cultural organizations in the United States were interviewed via telephone about their attitudes towards prenatal genetic counseling, prenatal genetic testing, and termination of pregnancy. Responses were transcribed and coded for common themes using a thematic analysis approach. Four major themes emerged. In general, participants: (1) had diverse expectations for genetic counselors; (2) tended to weigh risks and benefits with regards to genetic testing decisions; (3) had mixed views on termination for lethal and non‐lethal genetic conditions; and (4) identified cultural factors which influenced testing and termination such as lack of available resources, societal shame and stigma, and family pressure. These findings may allow prenatal genetic counselors to gain a richer, more nuanced understanding of their Asian patients and to offer culturally tailored prenatal genetic counseling.
Modeling information exchange between living and artificial cells
Authors: Heyde Keith C. , Rice MaryJoe K. , Paek Sung‐Ho , Scott Felicia Y. , Zhang Ruihua , Ruder Warren C. 
Published: March 2017

BackgroundThe tools of synthetic biology have enabled researchers to explore multiple scientific phenomena by directly engineering signaling pathways within living cells and artificial protocells. Here, we explored the potential for engineered living cells themselves to assemble signaling pathways for non‐living protocells. This analysis serves as a preliminary investigation into a potential origin of processes that may be utilized by complex living systems. Specifically, we suggest that if living cells can be engineered to direct the assembly of genetic signaling pathways from genetic biomaterials in their environment, then insight can be gained into how naturally occurring living systems might behave similarly.MethodsTo this end, we have modeled and simulated a system consisting of engineered cells that control the assembly of DNA monomers on microparticle scaffolds. These DNA monomers encode genetic circuits, and therefore, these microparticles can then be encapsulated with minimal transcription and translation systems to direct protocell phenotype. The modeled system relies on multiple previously established synthetic systems and then links these together to demonstrate system feasibility.ResultsIn this specific model, engineered cells are induced to synthesize biotin, which competes with biotinylated, circuit‐encoding DNA monomers for an avidinized‐microparticle scaffold. We demonstrate that multiple synthetic motifs can be controlled in this way and can be tuned by manipulating parameters such as inducer and DNA concentrations.ConclusionsWe expect that this system will provide insight into the origin of living systems as well as serve as a tool for engineering living cells that assemble complex biomaterials in their environment.
Consensus classification of posterior cortical atrophy
Authors: Crutch Sebastian J. , Schott Jonathan M. , Rabinovici Gil D. , Murray Melissa , Snowden Julie S. , van der Flier Wiesje M. , Dickerson Bradford C. , Vandenberghe Rik , Ahmed Samrah , Bak Thomas H. , Boeve Bradley F. , Butler Christopher , Cappa Stefano F. , Ceccaldi Mathieu , de Souza Leonardo Cruz , Dubois Bruno , Felician Olivier , Galasko Douglas , Graff‐Radford Jonathan , Graff‐Radford Neill R. , Hof Patrick R. , Krolak‐Salmon Pierre , Lehmann Manja , Magnin Eloi , Mendez Mario F. , Nestor Peter J. , Onyike Chiadi U. , Pelak Victoria S. , Pijnenburg Yolande , Primativo Silvia , Rossor Martin N. , Ryan Natalie S. , Scheltens Philip , Shakespeare Timothy J. , Suárez González Aida , Tang‐Wai David F. , Yong Keir X.X. , Carrillo Maria , Fox Nick C. ,   Alzheimer's Association ISTAART Atypical Alzheimer's Disease and Associated Syndromes Professional Interest Area
Published: March 2017

AbstractIntroductionA classification framework for posterior cortical atrophy (PCA) is proposed to improve the uniformity of definition of the syndrome in a variety of research settings.MethodsConsensus statements about PCA were developed through a detailed literature review, the formation of an international multidisciplinary working party which convened on four occasions, and a Web‐based quantitative survey regarding symptom frequency and the conceptualization of PCA.ResultsA three‐level classification framework for PCA is described comprising both syndrome‐ and disease‐level descriptions. Classification level 1 (PCA) defines the core clinical, cognitive, and neuroimaging features and exclusion criteria of the clinico‐radiological syndrome. Classification level 2 (PCA‐pure, PCA‐plus) establishes whether, in addition to the core PCA syndrome, the core features of any other neurodegenerative syndromes are present. Classification level 3 (PCA attributable to AD [PCA‐AD], Lewy body disease [PCA‐LBD], corticobasal degeneration [PCA‐CBD], prion disease [PCA‐prion]) provides a more formal determination of the underlying cause of the PCA syndrome, based on available pathophysiological biomarker evidence. The issue of additional syndrome‐level descriptors is discussed in relation to the challenges of defining stages of syndrome severity and characterizing phenotypic heterogeneity within the PCA spectrum.DiscussionThere was strong agreement regarding the definition of the core clinico‐radiological syndrome, meaning that the current consensus statement should be regarded as a refinement, development, and extension of previous single‐center PCA criteria rather than any wholesale alteration or redescription of the syndrome. The framework and terminology may facilitate the interpretation of research data across studies, be applicable across a broad range of research scenarios (e.g., behavioral interventions, pharmacological trials), and provide a foundation for future collaborative work.
MudGet: Reproduction of the desired lighting environment using a smart-LED
Authors: Kim Yong Hwi , Lee Yong Yi , Ahmed Bilal , Son Moon Gu , Choi Junho , Lee Jong Hun , Lee Kwan H. 
Published: March 2017

Abstract
With the emergence of smart LEDs, lighting based interior design is becoming popular. However, most of the smart LED-based lighting systems rely on expert-human intervention to create a desired atmosphere. For convenience, commercial lighting systems offer a number of options but their usability is fairly restricted. Therefore, an intuitive interface is required for novice users to generate the desired lighting environment. In this paper, we have developed a software, named MudGet, which automatically extracts the light mood from a digital image and controls the LED lamps to reproduce a desired lighting effect according to the extracted light mood. In our method, the light mood is regarded as a set of the representative colors of the digital image. The representative colors are extracted by utilizing K-means clustering algorithm. The dimming parameters are set for which each of the LED lamps create the lighting environment with the mood extracted by the software. To evaluate the feasibility of mood reproduction qualitatively, the degree of similarity between the light mood in the digital image and the reproduced result using LEDs is evaluated by a user study under a miniaturized experimental set. We observe that users can easily produce a desired atmosphere through the proposed MudGet software.
Highlights An image based lighting design interface is proposed. The interface controls customized LED module wirelessly. Desired lighting effect is generated from the color clustering centers of image.
Stable defects of minimizers of constrained variational principles
Authors: Lin Fang-Hua , Hardt R. , Kinderlehrer D. 
Published: March 2017

We prove energy and density bounds for minimizers of certain constrained variational problems, and we deduce limitations for their topological degree.

Résumé

On démontre des estimations
a priori
sur l’énergie et la densité des solutions de certains problèmes variationnels contraints, et l’on en déduit des bornes pour leur degréma topologique.
Holes and obstacles
Authors: Mancini Giovanni , Musina Roberta 
Published: March 2017

In this paper we investigate the effect of a partial obstacle on a semilinear elliptic B.V.P. which has, in general, no solution.
We show that highly unstable solutions arise, a phenomena previously observed for the same equation in presence of holes in the domain.

Résumé
Dans cet article nous examinerons l’effet d’un obstacle partiel pour un problème semi-linéaire elliptique au bord qui, en général, n’a pas de solution.
Nous montrons que des solutions hautement instables surgissent; il s’agit d’un phénomène précédemment observé pour le même genre d’équation, en présence de trous dams le domaine.
An asymptotic expansion for the solution of the generalized Riemann problem Part I: General theory
Authors: Le Floch Ph. , Raviart P.A. 
Published: March 2017

We consider the generalized Riemann problem for nonlinear hyperbolic systems of conservation laws. We show in this paper that we can find the entropy solution of this problem in the form of an asymptotic expansion in time and we give an explicit method of construction of this asymptotic expansion. Finally, we define from this expansion an approximate solution of the generalized Riemann problem and we give error bounds.

Résumé
On considère le problème de Riemann généralisé pour des systèmes hyperboliques non linéaires de lois de conservation. On trouve la solution entropique de ce problème sous la forme d’un développement asymptotique que l’on construit par une méthode explicite. On en déduit une solution approchée du problème de Riemann généralisé et l’on estime l’erreur.
On a free boundary problem for the stationary Navier-Stokes equations
Authors: Bemelmans Josef 
Published: March 2017

We investigate stationary flows in a fluid body together with its free boundary. The fluid is assumed to be viscous and incompressible; the free boundary is governed by continuity of the normal stress. Hence the configuration to be considered here can be regarded as a generalization of a classical equilibrium figure. The main tool in proving existence of a regular solution consists in a hard implicit function theorem.

Résumé
Nous étudions les flots stationnaires dans un corps fluide à frontière libre. Le liquide est supposé visqueux et incompressible; la frontière libre est régie par la continuité de la contrainte normale. Les configurations que nous examinons ici peuvent être regardées comme une généralisation d’une figure d’équilibre classique. L’outil principal pour démontré l’existence d’une solution régulière est un théorème de fonction implicite à la Nash–Moser.
Adult Co-morbidity Evaluation 27 scores of head and neck cancer patients using touch-screen technology: patient satisfaction and clinical verification
Authors: Brammer C , Dawson D , Joseph M , Tipper J , Jemmet T , Liew L , Spinou C , Grew N , Pigadas N , Rehman K 
Published: March 2017

AbstractObjectives:This study aimed to assess head and neck cancer patient satisfaction with the use of a touch-screen computer patient-completed questionnaire for assessing Adult Co-morbidity Evaluation 27 co-morbidity scores prior to treatment, along with its clinical reliability.Methods:A total of 96 head and neck cancer patients were included in the audit. An accurate Adult Co-morbidity Evaluation 27 co-morbidity score was achieved via patient-completed questionnaire assessment for 97 per cent of participants.Results:In all, 96 per cent of patients found the use of a touch-screen computer acceptable and would be willing to use one again, and 62 per cent would be willing to do so without help. Patients were more likely to be willing to use the computer again without help if they were aged 65 years or younger (χ2test;p= 0.0054) or had a performance status of 0 or 1 (χ2test;p= 0.00034).Conclusion:Use of a touch-screen computer is an acceptable approach for assessing Adult Co-morbidity Evaluation 27 scores at pre-treatment assessment in a multidisciplinary joint surgical–oncology clinic.
Prosodic development in European Portuguese from childhood to adulthood
Authors: FILIPE MARISA G. , PEPPÉ SUE , FROTA SÓNIA , VICENTE SELENE G. 
Published: March 2017

ABSTRACTWe describe the European Portuguese version of a test of prosodic abilities originally developed for English: the Profiling Elements of Prosody in Speech-Communication (Peppé & McCann, 2003). Using this test, we examined the development of several components of European Portuguese prosody between 5 and 20 years of age (N= 131). Results showed prosodic performance improving with age: 5-year-olds reach adultlike performance in the affective prosodic tasks; 7-year-olds mastered the ability to discriminate and produce short prosodic items, as well as the ability to understand question versus declarative intonation; 8-year-olds mastered the ability to discriminate long prosodic items; 9-year-olds mastered the ability to produce question versus declarative intonation, as well as the ability to identify focus; 10- to 11-year-olds mastered the ability to produce long prosodic items; 14- to 15-year-olds mastered the ability to comprehend and produce syntactically ambiguous utterances disambiguated by prosody; and 18- to 20-year-olds mastered the ability to produce focus. Cross-linguistic comparisons showed that linguistic form–meaning relations do not necessarily develop at the same pace across languages. Some prosodic contrasts are hard to achieve for younger Portuguese-speaking children, namely, the production of chunking and focus.
Bounding Sn(t) on the Riemann hypothesis
Authors: CARNEIRO EMANUEL , CHIRRE ANDRÉS 
Published: March 2017

AbstractLet $S(t) = {1}/{\pi} \arg \zeta \big(\hh + it \big)$ be the argument of the Riemann zeta-function at the point 1/2 + it. For n ⩾ 1 and t > 0 define its iterates

$$\begin{equation*}
S_n(t) = \int_0^t S_{n-1}(\tau) \,\d\tau\, + \delta_n\,,
\end{equation*}$$

where δn is a specific constant depending on n and S0(t) ≔ S(t). In 1924, J. E. Littlewood proved, under the Riemann hypothesis (RH), that Sn(t) = O(log t/(log log t)n + 1). The order of magnitude of this estimate was never improved up to this date. The best bounds for S(t) and S1(t) are currently due to Carneiro, Chandee and Milinovich. In this paper we establish, under RH, an explicit form of this estimate

$$\begin{equation*}
-\left( C^-_n + o(1)\right) \frac{\log t}{(\log \log t)^{n+1}} \ \leq \ S_n(t) \ \leq \ \left( C^+_n + o(1)\right) \frac{\log t}{(\log \log t)^{n+1}}\,,
\end{equation*}$$

for all n ⩾ 2, with the constants C±n decaying exponentially fast as n → ∞. This improves (for all n ⩾ 2) a result of Wakasa, who had previously obtained such bounds with constants tending to a stationary value when n → ∞. Our method uses special extremal functions of exponential type derived from the Gaussian subordination framework of Carneiro, Littmann and Vaaler for the cases when n is odd, and an optimized interpolation argument for the cases when n is even. In the final section we extend these results to a general class of L-functions.