bluuebunny/crossref_metadata_2025_split huggingface dataset:
Judaism - Jewish and Israeli pilgrimage experience: constructing national identity.
Authors: Inbari M. 
Published: January 2017

Abstract

This chapter provides contemporary and historical perspectives on Jewish pilgrimage. It reviews the tradition of Jewish pilgrimage to the ancient Temple, explains its purpose and meaning, and discusses the reasons for its termination. Modern pilgrimages to state-sponsored locations in Masada and to death camps in Poland such as Auschwitz-Birkenau, Majdenek and Treblinka are then be presented. The third type reviewed is a grassroots pilgrimage to a venerated saint's shrine which lies in Israel's periphery. It is argued that the modern Jewish pilgrimage experience continues an ancient custom (in the State of Israel and by diaspora), and it now exhibits both spiritual and national dimensions.
A convergence-guaranteed particle swarm optimization method for mobile robot global path planning
Authors: Tang Biwei , Zhanxia Zhu , Luo Jianjun 
Published: January 2017

Purpose
Aiming at obtaining a high-quality global path for a mobile robot which works in complex environments, a modified particle swarm optimization (PSO) algorithm, named random-disturbance self-adaptive particle swarm optimization (RDSAPSO), is proposed in this paper.

Design/methodology/approach
A perturbed global updating mechanism is introduced to the global best position to avoid stagnation in RDSAPSO. Moreover, a new self-adaptive strategy is proposed to fine-tune the three control parameters in RDSAPSO to dynamically adjust the exploration and exploitation capabilities of RDSAPSO. Because the convergence of PSO is paramount and influences the quality of the generated path, this paper also analytically investigates the convergence of RDSAPSO and provides a convergence-guaranteed parameter selection principle for RDSAPSO. Finally, a RDSAPSO-based global path planning (GPP) method is developed, in which the feasibility-based rule is applied to handle the constraint of the problem.

Findings
In an attempt to validate the proposed method, it is compared against six state-of-the-art evolutionary methods under three different numerical simulations. The simulation results confirm that the proposed method is highly competitive in terms of the path optimality. Moreover, the computation time of the proposed method is comparable with those of the other compared methods.

Originality/value
Therefore, the proposed method can be considered as a vital alternative in the field of GPP.
Mathematical model of robotic assembly by means of adaptation and low-frequency vibration
Authors: Vartanov Michael V. , Bojkova Leonarda V. , Zinina Inna N. 
Published: January 2017

Purpose
The purpose of this paper is to define the conditions for a failsafe coupling of parts when using adaptation and low-frequency vibrations. A model enables us to determine the reaction at the contact points of parts and time-based contact conditions changes. Therefore, the conditions of jamming parts can be defined in the process of conjugation.

Design/methodology/approach
A mathematical model describing the trajectory of the part mass center in robotic assembly is created. An experimental equipment is also presented in the paper. Convergence of theoretical and experimental results that characterize the reliability of processes is estimated.

Findings
The mathematical model of the connection process dynamics is found in the form of Lagrange’s equations of the second kind.

Originality/value
Applying low-frequency vibration and the adaptive gripper is proposed to extend technological capabilities of robotic assembly.
Design methodology for a hybrid part feeding system in lean-based assembly lines
Authors: Karadayi Usta Saliha , Oksuz Mehmet Kursat , Durmusoglu Mehmet Bulent 
Published: January 2017

Purpose
This paper aims to propose a combined methodology to help decision makers in evaluating and selecting the most effective part feeding system.

Design/methodology/approach
As a first step of the methodology, a hierarchical clustering analysis is applied to design a kitting or hybrid feeding system. Second, activity-based costing methodology is applied to determine which system is better according to their costs. Besides, sensitivity analysis is implemented to observe the behavior of the system in case of the takt time changes.

Findings
Using kitting systems purely can lead to problems because of the big and expensive parts in the mixed-model assembly systems. Therefore, the hybrid feeding policy can provide better solutions for such systems.

Research limitations/implications
A case study is conducted in a company and the most produced product of the company is considered to design the part feeding system. Results indicated that transportation cost has a large proportion on the total cost and the hybrid feeding policy may be a good solution to reduce this cost.

Practical implications
The paper includes implications for the design of hybrid feeding systems in lean-based assembly lines. The proposed methodology may be a practical tool for decision makers to design and decide on the part feeding policy.

Originality/value
Kitting design has not been studied yet to the best of the authors’ knowledge. Besides, there is no certain decision methodology indicating which system is better. In this study, different methods are combined as a new methodology with the purpose of industrial decision-making.
Escaping the healthcare leadership cul-de-sac
Authors: Edmonstone John Duncan 
Published: January 2017

Purpose
This paper aims to propose that healthcare is dominated by a managerialist ideology, powerfully shaped by business schools and embodied in the Masters in Business Administration. It suggests that there may be unconscious collusion between universities, healthcare employers and student leaders and managers.

Design/methodology/approach
Based on a review of relevant literature, the paper examines critiques of managerialism generally and explores the assumptions behind leadership development. It draws upon work which suggests that leading in healthcare organisations is fundamentally different and proposes that leadership development should be more practice-based.

Findings
The way forward for higher education institutions is to include work- or practice-based approaches alongside academic approaches.

Practical implications
The paper suggests that there is a challenge for higher education institutions to adopt and integrate practice-based development methods into their programme designs.

Originality/value
The paper provides a challenge to the future role of higher education institutions in developing leadership in healthcare.
An integrative discourse perspective on positive leadership in public health care
Authors: Pietiläinen Ville , Salmi Ilkka 
Published: January 2017

Purpose
This study aims to take a discursive view on positive leadership (PL). A positive approach has gained momentum in recent years as appropriate leadership practices are implemented in organizations. Despite the turn toward discursive approaches in organization studies, there is insufficient evidence supporting PL as a socially constructed experience.

Design/methodology/approach
The present study addresses an integrative discourse perspective for capturing the PL concept as a social process within the public health-care context.

Findings
Four meanings of PL are highlighted: role-taking, servicing, balancing and deciphering.

Research limitations/implications
The meanings shift the emphasis of certain PL definitions to a contextual interpretation. For scholars, the perspective demonstrates a multidimensional process approach in the desired organizational context as a counterbalance to one unanimously agreed-upon PL definition.

Practical implications
For leaders, an integrative discourse perspective offers tools for comprehending PL as a process: how to identify, negotiate and reconcile various PL meanings.

Originality/value
An integrative discourse perspective provides a novel perspective capturing the PL concept within the public health-care field.
Poor comprehenders in English‐only and English language learners: influence of morphological analysis during incidental word learning
Authors: Zhang Jie , Shulley Leah 
Published: January 2017

This study investigated whether weakness in using morphological analysis to infer new word meanings during reading is a source of poor text comprehension and the relative importance of psycholinguistic and cognitive factors as contributors of poor text comprehension in English‐only and English language learners. Thirty‐seven poor comprehenders and 44 typical readers in fourth and fifth grades in the United States were identified. Students were assessed on incidental word learning, vocabulary, morphological awareness, working memory and short‐term memory. Results showed that poor comprehenders were less able to use morphological analysis to interpret unfamiliar words while reading after controlling for vocabulary and morphological awareness. Vocabulary, morphological awareness and incidental word learning better discriminated the membership of poor comprehenders versus typical readers than working memory and short‐term memory in both English‐only and English language learners. The findings underscore the importance of lexical inferencing skills in reading comprehension regardless of language group.What is already known about this topic

Poor comprehenders have weaknesses in oral language and working memory.
Poor comprehenders have difficulties in some aspects of morphological awareness.
What this paper adds

Poor comprehenders are less able to use morphological analysis to interpret unfamiliar words while reading compared with typical readers.
Poor comprehenders display weakness in all aspects (relational, syntactic and structural) of morphological awareness.
Vocabulary, morphological awareness and incidental word learning can better classify poor comprehenders versus typical readers than working memory and short‐term memory.
Implications for theory, policy or practice

Cognitive and psycholinguistic profiles of English‐only and English language learners are highly similar.
Teachers should support the use of morphology while reading.
Does the Regulatory Environment Affect Nurse Practitioners’ Patterns of Practice or Quality of Care in Health Centers?
Authors: Kurtzman Ellen T. , Barnow Burt S. , Johnson Jean E. , Simmens Samuel J. , Infeld Donna Lind , Mullan Fitzhugh 
Published: January 2017

ObjectiveTo examine the impact of state‐granted nurse practitioner (NP) independence on patient‐level quality, service utilization, and referrals.Data Sources/Study SettingThe National Ambulatory Medical Care Survey's community health center (HC) subsample (2006–2011). Primary analyses included approximately 6,500 patient visits to 350 NPs in 220 HCs.Study DesignPropensity score matching and multivariate regression analysis were used to estimate the impact of state‐granted NP independence on each outcome, separately. Estimates were adjusted for sampling weights and NAMCS’s complex design.Data Collection/Extraction MethodsEvery “NP‐patient visit unit” was isolated using practitioner and patient visit codes and, using geographic identifiers, assigned to its state‐year and that state‐year's level of NP independence based on scope of practice policies. Nine outcomes were specified using ICD‐9 codes, standardized drug classification codes, and NAMCS survey items.Principal FindingsAfter matching, no statistically significant differences in quality were detected by states’ independence status, although NP visits in states with prescriptive independence received more educational services (aIRR 1.66; 95 percent CI 1.09–2.53; p = .02) and medications (aIRR 1.26; 95 percent CI 1.04–1.53; p = .02), and NP visits in states with practice independence had a higher odds of receiving physician referrals (AOR 1.88; 95 percent CI 1.10–3.22; p = .02) than those in restricted states.ConclusionsFindings do not support a quality–scope of practice relationship.
Importance of producing economic compounds to combat cancer
Authors: Muñoz‐Rojas Jesús 
Published: January 2017

SummaryThe manuscript published by Microb Biotechnol, volume 10, highlights the relevance of the fungus Nigrospora sphaerica, an endophyte isolated from Catharanthus roseus, as an alternative source to obtain vinblastine, a compound used in chemotherapy schemes to treat several types of cancer. Authors showed that purification of vinblastine from extracts of the fungus has higher activity and yield in comparison with that obtained from the plant Catharanthus roseus. This work represents a biotechnological approach to obtain vinblastine with promising results to decrease the production cost.
Selecting simultaneous actions of different durations to optimally manage an ecological network
Authors: Péron Martin , Jansen Cassie C. , Mantyka‐Pringle Chrystal , Nicol Sam , Schellhorn Nancy A. , Becker Kai Helge , Chadès Iadine 
Published: January 2017

Summary

Species management requires decision‐making under uncertainty. Given a management objective and limited budget, managers need to decide what to do, and where and when to do it. A schedule of management actions that achieves the best performance is an optimal policy. A popular optimisation technique used to find optimal policies in ecology and conservation is stochastic dynamic programming (SDP). Most SDP approaches can only accommodate actions of equal durations. However, in many situations, actions take time to implement or cannot change rapidly. Calculating the optimal policy of such problems is computationally demanding and becomes intractable for large problems. Here, we address the problem of implementing several actions of different durations simultaneously.

We demonstrate analytically that synchronising actions and their durations provide upper and lower bounds of the optimal performance. These bounds provide a simple way to evaluate the performance of any policy, including rules of thumb. We apply this approach to the management of a dynamic ecological network of Aedes albopictus, an invasive mosquito that vectors human diseases. The objective is to prevent mosquitoes from colonising mainland Australia from the nearby Torres Straits Islands where managers must decide between management actions that differ in duration and effectiveness.

We were unable to compute an optimal policy for more than eight islands out of 17, but obtained upper and lower bounds for up to 13 islands. These bounds are within 16% of an optimal policy. We used the bounds to recommend managing highly populated islands as a priority.

Our approach calculates upper and lower bounds for the optimal policy by solving simpler problems that are guaranteed to perform better and worse than the optimal policy respectively. By providing bounds on the optimal solution, the performance of policies can be evaluated even if the optimal policy cannot be calculated. Our general approach can be replicated for problems where simultaneous actions of different durations need to be implemented.
The water channel AQP1 is expressed in human atherosclerotic vascular lesions and AQP1 deficiency augments angiotensin II‐induced atherosclerosis in mice
Authors: Wintmo P. , Johansen S. H. , Hansen P. B. L. , Lindholt J. S. , Urbonavicius S. , Rasmussen L. M. , Bie P. , Jensen B. L. , Stubbe J. 
Published: January 2017

AbstractAimThe water channel aquaporin 1 (AQP1) promotes endothelial cell migration. It was hypothesized that AQP1 promotes neovascularization and growth of atherosclerotic plaques.MethodsAQP1 immunoreactivity and protein abundance was examined in human and murine atherosclerotic lesions and aortic aneurysms. Apolipoprotein E (ApoE) knockout (−/−) and AQP1−/−ApoE−/− mice were developed and fed Western diet (WD) for 8 and 16 weeks to accelerate the atherosclerosis process. In ApoE−/− and AQP1−/−ApoE−/− mice abdominal aortic aneurysms (AAA) were induced by angiotensin II (ANGII) infusion by osmotic minipumps for 4 weeks.ResultsIn human atherosclerotic lesions and AAA, AQP1 immunoreactive protein was associated with intralesional small vessels. In ApoE−/− mouse aorta, APQ1 mRNA levels were increased with time on WD (n = 7–9, P < 0.003). Both in murine lesions at the aortic root and in the abdominal aortic aneurysmal wall, AQP1 immunoreactivity was associated with microvascular structures. The atherosclerotic lesion burden was enhanced significantly in ANGII‐infused AQP1−/−ApoE−/− mice compared with ApoE−/− mice, but neither incidence nor progression of AAA was different. The aortic lesion burden increased with time on WD but was not different between ApoE−/− and AQP1−/−ApoE−/− mice at either 8 or 16 weeks (n = 13–15). Baseline blood pressure and ANGII‐induced hypertension were not different between genotypes.ConclusionAQP1 is expressed in atherosclerotic lesion neovasculature in human and mouse arteries and AQP1 deficiency augments lesion development in ANGII‐promoted atherosclerosis in mice. Normal function of AQP1 affords cardiovascular protection.
Nocturia increases the incidence of depressive symptoms: a longitudinal study of the HEIJO‐KYO cohort
Authors: Obayashi Kenji , Saeki Keigo , Negoro Hiromitsu , Kurumatani Norio 
Published: January 2017

ObjectivesTo evaluate the association between nocturia and the incidence of depressive symptoms.Participants and MethodsOf 1 127 participants in the HEIJO‐KYO population‐based cohort, 866 elderly individuals (mean age 71.5 years) without depressive symptoms at baseline were followed for a median period of 23 months. Nocturnal voiding frequency was logged using a standardized urination diary and nocturia was defined as a frequency of ≥2 voids per night. Depressive symptoms were assessed using the Geriatric Depression Scale.ResultsDuring the follow‐up period, 75 participants reported the development of depressive symptoms (score ≥6). The nocturia group (n = 239) exhibited a significantly higher hazard ratio (HR) for incident depressive symptoms than the non‐nocturia group (n = 627) in the Cox proportional hazard model, which was adjusted for age, gender, alcohol consumption, day length and presence of hypertension and chronic kidney disease (HR 1.69, 95% confidence interval [CI] 1.05–2.72; P = 0.032]. The significance remained after adjustment for sleep disturbances (HR 1.68, 95% CI 1.02–2.75; P = 0.040). Analysis stratified by gender showed that the association between nocturia and the incidence of depressive symptoms was significant in men (HR 2.51, 95% CI 1.27–4.97; P = 0.008) but not in women (HR 1.12, 95% CI 0.53–2.44; P = 0.74).ConclusionsNocturia is significantly associated with a higher incidence of depressive symptoms in the general elderly population, and gender differences may underlie this association.
A key role for tetrahydrobiopterin‐dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin‐deficient mice
Authors: Chuaiphichai Surawee , Crabtree Mark J , Mcneill Eileen , Hale Ashley B , Trelfa Lucy , Channon Keith M , Douglas Gillian 
Published: January 2017

Background and PurposeThe cofactor tetrahydrobiopterin (BH4) is a critical regulator of endothelial NOS (eNOS) function, eNOS‐derived NO and ROS signalling in vascular physiology. To determine the physiological requirement for de novo endothelial cell BH4 synthesis for the vasomotor function of resistance arteries, we have generated a mouse model with endothelial cell‐specific deletion of Gch1, encoding GTP cyclohydrolase 1 (GTPCH), an essential enzyme for BH4 biosynthesis, and evaluated BH4‐dependent eNOS regulation, eNOS‐derived NO and ROS generation.Experimental ApproachThe reactivity of mouse second‐order mesenteric arteries was assessed by wire myography. High performance liquid chromatography was used to determine BH4, BH2 and biopterin. Western blotting was used for expression analysis.Key ResultsGch1fl/flTie2cre mice demonstrated reduced GTPCH protein and BH4 levels in mesenteric arteries. Deficiency in endothelial cell BH4 leads to eNOS uncoupling, increased ROS production and loss of NO generation in mesenteric arteries of Gch1fl/flTie2cre mice. Gch1fl/flTie2cre mesenteric arteries had enhanced vasoconstriction to U46619 and phenylephrine, which was abolished by L‐NAME. Endothelium‐dependent vasodilatations to ACh and SLIGRL were impaired in mesenteric arteries from Gch1fl/flTie2cre mice, compared with those from wild‐type littermates. Loss of eNOS‐derived NO‐mediated vasodilatation was associated with increased eNOS‐derived H2O2 and cyclooxygenase‐derived vasodilator in Gch1fl/flTie2cre mesenteric arteries.Conclusions and ImplicationsEndothelial cell Gch1 and BH4‐dependent eNOS regulation play pivotal roles in maintaining vascular homeostasis in resistance arteries. Therefore, targeting vascular Gch1 and BH4 biosynthesis may provide a novel therapeutic target for the prevention and treatment of microvascular dysfunction in patients with cardiovascular disease.
Working with the whole family: What case files tell us about social work practices
Authors: Laird Siobhan E. , Morris Kate , Archard Philip , Clawson Rachael 
Published: January 2017

AbstractPractice theories to support child protection social work in the United Kingdom, as in the United States and Australia, are being squeezed out by a focus on performance targets and procedural timescales. This study examines an innovative programme designed to reverse this trend initiated by an English local government authority. The programme aimed to embed systemic family practice in situations where children are deemed to be at risk of harm. The findings, derived from an analysis of a case file sample, indicate that the social worker interaction with family members is predicated on who is living with the child in conjunction with the risk status of the case file. Conversely, practitioner interactions with family members are divorced from family structure and the lived experiences of kin relationships. This study concludes by examining why, despite training in systemic family practice, it was problematic for social workers to integrate it into their encounters with families.
Eosinophilic intestinal diseases of the horse
Authors: Schumacher J. , Legere R. 
Published: January 2017

SummaryEosinophilic intestinal diseases of the horse are not commonly reported. Similar diseases are reported in man, but for either species, these eosinophilic diseases, are poorly understood. Eosinophilic intestinal disease may be accompanied by eosinophilic disease of other organs, or eosinophilia may be restricted to the intestine. When infiltration of eosinophils is restricted to the intestine, horses have a good prognosis for resolution of clinical signs, even though the treatment may include celiotomy with intestinal decompression or resection and administration of a corticosteroid. When eosinophilic intestinal disease is accompanied by infiltration of other organs, such as skin, pancreas, lungs or liver, the horse's prognosis for survival is very poor.