bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Transitional Cell Carcinoma of Fallopian Tube in Postmenopausal Women: A Case Report and Review of Literature
Authors: Vijayaraghavan Jaya , Bhuvana S , Indumathi KPK 
Published: June 2017

ABSTRACT
Introduction
Primary fallopian tube carcinoma is the least common gynecological malignancy encountered in practice. It accounts for about 1% of all cancers of a woman’s reproductive system, and it is more commonly seen in postmenopausal women. Transitional cell carcinoma (TCC) of the fallopian tube is a rare histological variant; only around 20 cases have been reported worldwide so far. The rate of preoperative diagnosis is in the range of 0 to 10%.

Case report
A 55-year-old P3L3 previous three normal vaginal delivery, postmenopausal for 6 years, type II diabetes mellitus patient presented with complaints of bleeding per vagina and excessive watery discharge per vagina for 6 months. Complete investigations and evaluation were done. Papanicolaou smear and endometrial aspiration were normal, and showed no evidence of malignancy. Taking age into consideration with duration of symptoms for 6 months, we went ahead with total abdominal hysterectomy with bilateral salpingo-oophorectomy. Intraoperatively, right hydrosalpinx was noted. Postoperatively, histopathology revealed right TCC of fallopian tube stage Ta1 Nx M0. Patient had wound infection postoperatively and was treated with IV antibiotics. Once infection settled, patient was taken up for diagnostic laparoscopy with omental biopsy and cystoscopy with bladder wall biopsy, which showed no evidence of malignancy.

Conclusion
It is more common for other cancers to spread to the fallopian tubes rather than for cancer to begin there. This diagnosis is rarely considered preoperatively and is usually first appreciated at the time of operation or by a pathologist. If detected early, fallopian tube cancer can often be successfully treated.

How to cite this article
Indumathi KPK, Bhuvana S, Vijayaraghavan J. Primary Transitional Cell Carcinoma of Fallopian Tube in Postmenopausal Women: A Case Report and Review of Literature. J South Asian Feder Menopause Soc 2017;5(1):58-61.
Krukenberg Tumor from Gastric Carcinoma presented as Acute Abdomen: A Unique Presentation
Authors: Jarathi Aparna , Ramamoorthy Sowbarnika , Mohan Jayanthi 
Published: June 2017

ABSTRACT
Krukenberg tumor is an ovarian metastatic tumor from the digestive tract accounting for 10% of all ovarian malignancies. The uniqueness of this tumor is its morphology disguising as the primary tumor. We present a case of gastric carcinoma in a 36-year-old woman, who presented as acute abdomen to the emergency department. Abdominal examination revealed tender, cystic to firm mass of size 14 × 10 × 8 cm in the left lower quadrant. The abdominal ultrasonography revealed the ovarian mass of the above-mentioned size with minimal free fluid in the peritoneal cavity. An explorative laparotomy disclosed bilateral ovarian masses. Histological findings of both ovarian masses were consistent with metastatic adenocarcinoma of stomach. The survival rate of the patients can be improved by tumor-free surgery and a novel platinum-based chemotherapy. Krukenberg tumor should be considered in differential diagnosis of acute abdomen.
How to cite this article
Jarathi A, Ramamoorthy S, Mohan J. Krukenberg Tumor from Gastric Carcinoma presented as Acute Abdomen: A Unique Presentation. J South Asian Feder Menopause Soc 2017;5(1):66-68.
Comparisons of the Orbiting Carbon Observatory-2 (OCO-2) XCO2 measurements with TCCON
Authors: Wunch Debra , Wennberg Paul O. , Osterman Gregory , Fisher Brendan , Naylor Bret , Roehl Coleen M. , O'Dell Christopher , Mandrake Lukas , Viatte Camille , Kiel Matthäus , Griffith David W. T. , Deutscher Nicholas M. , Velazco Voltaire A. , Notholt Justus , Warneke Thorsten , Petri Christof , De Maziere Martine , Sha Mahesh K. , Sussmann Ralf , Rettinger Markus , Pollard David , Robinson John , Morino Isamu , Uchino Osamu , Hase Frank , Blumenstock Thomas , Feist Dietrich G. , Arnold Sabrina G. , Strong Kimberly , Mendonca Joseph , Kivi Rigel , Heikkinen Pauli , Iraci Laura , Podolske James , Hillyard Patrick W. , Kawakami Shuji , Dubey Manvendra K. , Parker Harrison A. , Sepulveda Eliezer , García Omaira E. , Te Yao , Jeseck Pascal , Gunson Michael R. , Crisp David , Eldering Annmarie 
Published: June 2017

Abstract. NASA's Orbiting Carbon Observatory-2 (OCO-2) has been measuring carbon dioxide column-averaged dry-air mole fraction, XCO2, in the Earth's atmosphere for over 2 years. In this paper, we describe the comparisons between the first major release of the OCO-2 retrieval algorithm (B7r) and XCO2 from OCO-2's primary ground-based validation network: the Total Carbon Column Observing Network (TCCON). The OCO-2 XCO2 retrievals, after filtering and bias correction, agree well when aggregated around and coincident with TCCON data in nadir, glint, and target observation modes, with absolute median differences less than 0.4 ppm and RMS differences less than 1.5 ppm. After bias correction, residual biases remain. These biases appear to depend on latitude, surface properties, and scattering by aerosols. It is thus crucial to continue measurement comparisons with TCCON to monitor and evaluate the OCO-2 XCO2 data quality throughout its mission.
Les objets connectés peuvent-ils susciter une résistance de la part des consommateurs ? Une étude netnographique
Authors: Chouk Inès , Mani Zied 
Published: June 2017

Cette recherche se focalise sur la résistance aux objets connectés exprimée par le consommateur sur le web. Elle apporte un éclairage sur les freins à l’utilisation des objets connectés et aux facteurs susceptibles d’entraver leur développement. L’étude netnographique réalisée a permis d’identifier trois types de facteurs de résistance : des facteurs liés au système, des facteurs liés aux objets connectés et des facteurs liés au consommateur. En outre, elle a mis en évidence deux formes d’expression de la résistance : le discours « complotiste » et le discours « rationnel ».
Curriculum goals for the training of osteopathic family practice residents for the year 2000
Authors: Dickerman Joel , Rich Pamela 
Published: June 2017

Abstract
The osteopathic family practitioner of the future will play a larger role in the delivery of healthcare under managed care. To prepare for this role, osteopathic family practice residents must develop skills in direct medical care, medical education, and healthcare administration. Likewise, these residents need to become familiar with the clinical setting in which these skills are needed, specifically, ambulatory, rural, hospital, and minor emergency care environments. We propose the development of a curriculum designed to promote these skills and clinical experiences. This curriculum would expand family practice experiences; replace the current required rotations in specialty medicine with longitudinal rotations designed to develop specific family practice skills; include block rotations in hospital care, minor emergency care, and rural medicine; develop model case assignments to teach residents. to integrate their roles as provider, educator, and administrator; and entail clinical experiences in medical administration and education. An evaluation process that reflects the goals of the family practice curriculum is key to the success of such a program.
Ambulatory care training standards for continuity of care in osteopathic family medicine
Authors: Winters Frank D. , Zonia Susan , Cook, Joseph N. , Dora David L. , Meyer Christopher T. 
Published: June 2017

Abstract
The authors developed statewide standards of excellence for ambulatory care training in an osteopathic medical consortium of family medicine residency programs. A total of 16 osteopathic family medicine residency programs joined with the Michigan State University-College of Osteopathic Medicine to form the Consortium for Osteopathic Graduate Medical Education Training (COGMET) Family Medicine Division. Standards were developed and implemented on a statewide basis for all member residency programs. Initial qualitative evaluations discovered minor as well as more substantive noncompliance after a 6-month trial. Results from longitudinal quantitative evaluations will determine the effectiveness of these standards-.
Cytoplasmic expression of C-MYC protein is associated with risk stratification of mantle cell lymphoma
Authors: Gong Yi , Zhang Xi , Chen Rui , Wei Yan , Zou Zhongmin , Chen Xinghua 
Published: June 2017

AimTo investigate the association of C-MYC protein expression and risk stratification in mantle cell lymphoma (MCL), and to evaluate the utility of C-MYC protein as a prognostic biomarker in clinical practice.MethodsWe conducted immunohistochemical staining of C-MYC, Programmed cell death ligand 1 (PD-L1), CD8, Ki-67, p53 and SRY (sex determining region Y) -11 (SOX11) to investigate their expression in 64 patients with MCL. The staining results and other clinical data were evaluated for their roles in risk stratification of MCL cases using ANOVA, Chi-square, and Spearman’s Rank correlation coefficient analysis.ResultsImmunohistochemical staining in our study indicated that SOX11, Ki-67 and p53 presented nuclear positivity of tumor cells, CD8 showed membrane positivity in infiltrating T lymphocytes while PD-L1 showed membrane and cytoplasmic positivity mainly in macrophage cells and little in tumor cells. We observed positive staining of C-MYC either in the nucleus or cytoplasm or in both subcellular locations. There were significant differences in cytoplasmic C-MYC expression, Ki-67 proliferative index of tumor cells, and CD8 positive tumor infiltrating lymphocytes (CD8+TIL) among three risk groups (P = 0.000,P = 0.037 andP=0.020, respectively). However, no significant differences existed in the expression of nuclear C-MYC, SOX11, p53, and PD-L1 in MCL patients with low-, intermediate-, and high risks. In addition, patient age and serum LDH level were also significantly different among 3 groups of patients (P = 0.006 andP = 0.000, respectively). Spearman’s rank correlation coefficient analysis indicated that cytoplasmic C-MYC expression, Ki-67 index, age, WBC, as well as LDH level had significantly positive correlations with risk stratification (P = 0.000, 0.015, 0.000, 0.029 and 0.000, respectively), while CD8+TIL in tumor microenvironment negatively correlated with risk stratification of patients (P = 0.006). Patients with increased positive cytoplasmic expression of C-MYC protein and decreased CD8+TIL appeared to be associated with a poor response to chemotherapy, but the correlation was not statistically significant.ConclusionOur study suggested that assessment of cytoplasmic C-MYC overexpression and cytotoxic T lymphocytes (CTLs) by immunohistochemical staining might be helpful for MCL risk stratification and outcome prediction. However, large cohort studies of MCL patients with complete follow up are needed to validate our speculation.
Microwave retrievals of terrestrial precipitation over snow‐covered surfaces: A lesson from the GPM satellite
Authors: Ebtehaj A. M. , Kummerow C. D. 
Published: June 2017

AbstractSatellites are playing an ever‐increasing role in estimating precipitation over remote areas. Improving satellite retrievals of precipitation requires increased understanding of its passive microwave signatures over different land surfaces. Snow‐covered surfaces are notoriously difficult to interpret because they exhibit both emission from the land below and scattering from the ice crystals. Using data from the Global Precipitation Measurement (GPM) satellite, we demonstrate that microwave brightness temperatures of rain and snowfall transition from a scattering to an emission regime from summer to winter, due to expansion of less emissive snow cover. Evidence suggests that the combination of low‐ (10–19 GHz) and high‐frequency (89–166 GHz) channels provides the maximum amount of information for snowfall detection. The results demonstrate that, using a multifrequency matching method, the probability of snowfall detection can even be higher than rainfall—chiefly because of the information content of the low‐frequency channels that respond to the (near) surface temperature.
SAMI3 prediction of the impact of the 21 August 2017 total solar eclipse on the ionosphere/plasmasphere system
Authors: Huba J. D. , Drob D. 
Published: June 2017

AbstractWe present quantitative predictions of the impact of the upcoming total solar eclipse on the ionosphere and plasmasphere using the Naval Research Laboratory (NRL) model Sami3 is Also a Model of the Ionosphere (SAMI3). The eclipse will occur over the continental United States on 21 August 2017. Our simulation results indicate that in the vicinity of the eclipse (1) the total electron content (TEC) decreases by up to ∼ 5 TEC units (TECU; 1 TECU = ×1016 m−2) which is a ∼ 35% decrease in TEC, (2) the electron density decreases by a factor of ∼ 50% in the F region, (3) the electron temperature decreases by up to ∼800 K in the plasmasphere, and (4) the O+ velocity changes from ∼40 m s−1 upward to ∼20 m s−1 downward in the F region. Interestingly, the continental size modification of the ionospheric conductance modifies the global electric field, which should lead to measurable changes in the TEC in the southern conjugate hemisphere (
1 TECU).
Multi vegetation model evaluation of the Green Sahara climate regime
Authors: Hopcroft Peter O. , Valdes Paul J. , Harper Anna B. , Beerling David J. 
Published: June 2017

AbstractDuring the Quaternary, the Sahara desert was periodically colonized by vegetation, likely because of orbitally induced rainfall increases. However, the estimated hydrological change is not reproduced in climate model simulations, undermining confidence in projections of future rainfall. We evaluated the relationship between the qualitative information on past vegetation coverage and climate for the mid‐Holocene using three different dynamic vegetation models. Compared with two available vegetation reconstructions, the models require 500–800 mm of rainfall over 20°–25°N, which is significantly larger than inferred from pollen but largely in agreement with more recent leaf wax biomarker reconstructions. The magnitude of the response also suggests that required rainfall regime of the early to middle Holocene is far from being correctly represented in general circulation models. However, intermodel differences related to moisture stress parameterizations, biases in simulated present‐day vegetation, and uncertainties about paleosoil distributions introduce uncertainties, and these are also relevant to Earth system model simulations of African humid periods.
On the micromechanics of slip events in sheared, fluid‐saturated fault gouge
Authors: Dorostkar Omid , Guyer Robert A. , Johnson Paul A. , Marone Chris , Carmeliet Jan 
Published: June 2017

AbstractWe used a three‐dimensional discrete element method coupled with computational fluid dynamics to study the poromechanical properties of dry and fluid‐saturated granular fault gouge. The granular layer was sheared under dry conditions to establish a steady state condition of stick‐slip dynamic failure, and then fluid was introduced to study its effect on subsequent failure events. The fluid‐saturated case showed increased stick‐slip recurrence time and larger slip events compared to the dry case. Particle motion induces fluid flow with local pressure variation, which in turn leads to high particle kinetic energy during slip due to increased drag forces from fluid on particles. The presence of fluid during the stick phase of loading promotes a more stable configuration evidenced by higher particle coordination number. Our coupled fluid‐particle simulations provide grain‐scale information that improves understanding of slip instabilities and illuminates details of phenomenological, macroscale observations.
The citation impact of hydrology journals
Authors: Clark Martyn P. , Hanson R. Brooks 
Published: June 2017

AbstractWe examine a suite of journal‐level productivity and citation statistics for six leading hydrology journals in order to help authors understand the robustness and meaning of journal impact factors. The main results are (1) the probability distribution of citations is remarkably homogenous across hydrology journals; (2) hydrology papers tend to have a long‐lasting impact, with a large fraction of papers cited after the 2 year window used to calculate the journal impact factor; and (3) journal impact factors are characterized by substantial year‐to‐year variability (especially for smaller journals), primarily because a small number of highly cited papers have a large influence on the journal impact factor. Consequently, the ranking of hydrology journals with respect to the journal impact factor in a given year does not have much information content. These results highlight problems in using citation data to evaluate hydrologic science. We hope that this analysis helps authors better understand journal‐level citation statistics, and also helps improve research assessments in institutions and funding agencies.
α,α‐Difluoro‐α‐(trimethylsilyl)acetamides as Versatile Reagents for the Preparation of Difluorinated Aldol and Mannich Adducts
Authors: Honraedt Aurélien , Van Der Lee Arie , Campagne Jean‐Marc , Leclerc Eric 
Published: June 2017

AbstractThe very efficient addition of α,α‐difluoro‐α‐(trimethylsilyl)acetamides to aldehydes, ketones and N‐(tert‐butanesulfinyl)imines is described. The reaction is promoted by a catalytic amount of tetra‐n‐butylammonium diphenyltrifluorosilicate (TBAT) and high yields, as well as very high stereoselectivities in the case of N‐(tert‐butanesulfinyl)imines, are achieved. The synthetic potential of this method is illustrated by the conversion of the resulting products to β‐hydroxy ketones, diols and β‐amino alcohols by addition of various Grignard reagents or reduction of the amide moiety.magnified image
Waist‐to‐height ratio and its association with TV viewing in a sample of Portuguese children aged 7–9 years
Authors: Machado‐Rodrigues Aristides M. , Valente‐dos‐Santos João , Fernandes Romulo , Gama Augusta , Mourao Isabel , Nogueira Helena , Marques Vitor , Padez Cristina 
Published: June 2017

AbstractINTRODUCTIONDuring the past decades, increased TV viewing and reduced physical activity (PA) levels may have contributed to the increased prevalence of pediatric obesity. This study aimed to analyze the association between TV viewing and central adiposity risk in Portuguese children.METHODSThe sample comprised 3987 children (1997 girls and 1990 boys) aged 7–9 years. Height, weight, and waist circumference (WC) were measured. Waist‐to‐height ratio (WHtR) was calculated as the ratio of waist/height with a cut‐off of 0.5 used to define risk of abdominal obesity. WHtR does not depend on sex‐ or age‐specific reference criteria. TV viewing and PA were assessed by questionnaire. Logistic regressions were used, with adjustments for age, PA, and parental education.RESULTSThis study revealed a positive significant association between central adiposity risk and sedentary behaviors in Portuguese boys. In addition, the final model showed an important inverse association between PA and the risk of abdominal obesity in both boys and girls (males: β = −0.01 95% CI, 0.99 to 1.00; females: β = −0.01; 95% CI, 0.99‐1.00).CONCLUSIONFindings revealed that associations between TV viewing and obesity risk could be highly influenced by socioeconomic factors. Future research should extend a similar design to children in other geographic contexts, and incorporate other behavioral variables in the statistical models, to confirm or not some of the aforementioned findings.
SN2 Reactions at Tertiary Carbon Centers in Epoxides
Authors: Zhang Yong‐Qiang , Poppel Christina , Panfilova Anastasia , Bohle Fabian , Grimme Stefan , Gansäuer Andreas 
Published: June 2017

AbstractDescribed herein is a novel concept for SN2 reactions at tertiary carbon centers in epoxides without activation of the leaving group. Quantum chemical calculations show why SN2 reactions at tertiary carbon centers are proceeding in these systems. The reaction allows flexible synthesis of 1,3‐diol building blocks for natural product synthesis with excellent control of the relative and absolute configurations.
Student and recent graduate perspectives on radiological imaging instruction during basic anatomy courses
Authors: Phillips Andrew W. , Eason Hunter , Straus Christopher M. 
Published: June 2017

Recently, faculty at Pritzker School of Medicine, The University of Chicago, have made efforts to improve the depth of radiological anatomy knowledge that students have, but no insights exist as to student and resident opinions of how clinically helpful deep anatomical understanding is. A single‐institution survey of second‐ and fourth‐year medical students and postgraduate year 1–4 residents from 11 specialties, composed of five‐point Likert questions, sample examination questions, and narrative response questions, was distributed in 2015. One hundred seventy‐seven of the 466 potential respondents replied (71 residents and 106 students), response rate 38.0%. No nonresponse bias was present in two separate analyses. Respondents generally favored a superficial “identification” question as more relevant to clinical practice, which was positively associated with increasing clinical experience ρ = 0.357, P < 0.001 by point‐biserial correlation. Students and residents most commonly used self‐directed methods to learn medical imaging during their medical anatomy courses (72.6 and 57.7%, respectively). Small group education was least commonly used by students and residents (45.3 and 39.4%, respectively), but most commonly recommended (62.3 and 69%, respectively). A total of 56.6 and 64.8% of students and residents, respectively, reported that having multiple learning methods was “quite” or “extremely” important. Respondents with more clinical experience were more likely to report that a superficial identification question was more clinically relevant than a question testing deeper radiological anatomy knowledge. Small group learning was preferred among students and residents but was the least commonly employed method of instruction. Both findings contrast starkly with current radiological anatomy instructional understanding and practices. Anat Sci Educ 11: 25–31. © 2017 American Association of Anatomists.
“Two‐Point” Self‐Assembly and Photoinduced Electron Transfer in meso‐Donor‐Carrying Bis(styryl crown ether)‐BODIPY–Bis(alkylammonium)fullerene Donor–Acceptor Conjugates
Authors: Shao Shuai , Gobeze Habtom B. , Karr Paul A. , D'Souza Francis 
Published: June 2017

AbstractBF2‐chelated dipyrromethene, BODIPY, was functionalized to carry two styryl crown ether tails and a secondary electron donor at the meso position. By using a “two‐point” self‐assembly strategy, a bis‐alkylammonium‐functionalized fullerene (C60) was allowed to self‐assemble the crown ether voids of BODIPY to obtain multimodular donor–acceptor conjugates. As a consequence of the two‐point binding, the 1:1 stoichiometric complexes formed yielded complexes of higher stability in which fluorescence of BODIPY was found to be quenched; this suggested the occurrence of excited‐state processes. The geometry and electronic structure of the self‐assembled complexes were derived from B3LYP/3‐21G(*) methods in which no steric constraints between the entities was observed. An energy‐level diagram was established by using spectral, electrochemical, and computational results to help understand the mechanistic details of excited‐state processes originating from 1bis‐styryl‐BODIPY*. Femtosecond transient absorbance studies were indicative of the formation of an exciplex state prior to the charge‐separation process to yield a bis‐styryl‐BODIPY.+–C60.− radical ion pair. The time constants for charge separation were generally lower than charge‐recombination processes. The present studies bring out the importance of multimode binding strategies to obtain stable self‐assembled donor–acceptor conjugates capable of undergoing photoinduced charge separation needed in artificial photosynthetic applications.