bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nomenclatural notes on Nadsoniella and the human opportunist black yeast genus Exophiala
Authors: Moussa Tarek A. A. , Al‐Zahrani Hassan S. , Kadasa Naif M. S. , Moreno Leandro F. , Gerrits van den Ende A. H. G. , de Hoog G. Sybren , Al‐Hatmi Abdullah M. S. 
Published: January 2017

SummaryThe opportunistic black yeast are particularly known through the genus Exophiala, characterised by annellidic budding cells. However, this phenotype is polyphyletic within the order Chaetothyriales. Seventeen generic names are available in the family Herpotrichiellaceae, one of which is Exophiala. Future taxonomy will be based on molecular phylogeny; each multi‐species clade may qualify for one of these names. This paper focuses on the genus Nadsoniella, which is the oldest valid name in the Herpotrichiellaceae. Despite its exophiala‐like phenotype, the type species of Nadsoniella clusters in the jeanselmei‐clade, competing with the sympodial genus Rhinocladiella. In contrast, Exophiala competes with morphologically pronounced genera Thysanorea and Veronaea. Replacing the current phenotypic system for phylogenetic nomenclature requires highly stable phylogenies, which currently are not available.
Meaningful Materials? Bone Artefacts and Symbolism in the Early Bronze Age Aegean
Authors: Isaakidou Valasia 
Published: January 2017

SummaryThe symbolically laden use of materials is well documented ethnographically but hard to demonstrate archaeologically, especially for animal bones and teeth, use of which in post‐Neolithic contexts is commonly considered expedient. Early Bronze Age southern Aegean mortuary assemblages have yielded three distinctive classes of bone artefact. Comparison with contemporary unworked bone assemblages and contextually or formally related objects in other materials reveals complex cultural associations, the symbolic meaning of which is explored through heuristic use of ethnographic analogues. It is concluded that alternative value systems operated alongside those structured around exoticism and technological sophistication, usually deployed to understand EBA southern Aegean cultures.
Transient Neonatal Zinc Deficiency Caused by a Novel Mutation in the SLC30A2 Gene
Authors: Liew Hui M. , Tan Colin W. , Ho Clement K. M. , Chee Jade N. , Koh Mark J. A. 
Published: January 2017

AbstractThis is a case report of a 4‐month‐old full‐term, fully breastfed boy who presented with a persistent periorificial and groin rash associated with poor weight gain and irritability. His serum zinc level was low. The mother's breast milk zinc level was found to be low despite her serum zinc levels being normal, confirming the diagnosis of transient neonatal zinc deficiency. Mutational analysis revealed a novel mutation in the mother's SLC30A2 gene, which encodes a zinc transporter expressed in mammary gland epithelial cells.
Dermoscopy of Papular Epidermal Nevus with Skyline Basal Cell Layer
Authors: Balestri Riccardo , Rizzoli Laura , Rech Giulia , Girardelli Carlo Renè 
Published: January 2017

AbstractPapular epidermal nevus with skyline basal cell layer (PENS) is a newly described keratinocytic nevus whose dermoscopic characteristics have not been clarified. We used a dermatoscope to investigate the multiple PENSs of a patient with PENS syndrome. All the lesions shared a common dermoscopic homogeneous white pattern surrounded by peripheral, slightly dotted hyperpigmentation. The smallest lesions had no other features, whereas the largest lesions had some scaling, directly proportional to their dimension, and a central, clear, pink discoloration.
Dynamic changes in mitochondrial DNA, distribution and activity within cat oocytes during folliculogenesis
Authors: Songsasen N , Henson LH , Tipkantha W , Thongkittidilok C , Henson JH , Chatdarong K , Comizzoli P 
Published: January 2017

ContentsMitochondria play fundamental roles during oocyte development. The accumulation and spatial redistribution of these energy‐producing organelles have been linked to the developmental competence of mammalian oocytes. Here, we assessed the copy number, distribution and activity of mitochondria within cat oocytes during folliculogenesis. In Experiment 1, oocytes were recovered from primordial (n = 152), primary (112), secondary (95), early (131), small (118), antral (86) and advanced antral (5) stages follicles, and mitochondria DNA extracted and quantified using qPCR. In Experiment 2, oocytes from pre‐antral (n = 44), early antral (n = 66), small antral (n = 59), antral (n = 41) and advanced antral (n = 21) follicles were isolated and stained with CMXRos MitoTracker dye to assess mitochondrial distribution pattern and activity levels. Oocyte's mitochondria DNA (mtDNA) copy numbers gradually increased as folliculogenesis progressed, with a significant shift at the small antral stage (0.5 to <1 mm in diameter). The location of mitochondria gradually shifted from a homogeneous distribution throughout the cytoplasm in pre‐antral oocytes to a pericortical concentration in the advanced antral stage. Quantification of CMXRos fluorescent intensity revealed a progressive increase in mitochondrial activity in oocytes from the pre‐antral to the large antral follicles. Taken together, these findings demonstrated that cat oocytes undergo dynamic changes in mitochondrial copy number, distribution and activity during folliculogenesis. These significant modifications to this crucial cytoplasmic organelle are likely associated with the acquisition of developmental competency by cat oocytes.
The influence of compost and zeolite co‐addition on the nutrients status and plant growth in intensively cultivated Mediterranean soils
Authors: Litaor M. I. , Katz L. , Shenker M. 
Published: January 2017

AbstractThe main objective of the study was to test the benefits of compost and zeolite co‐addition on the fertility of organic‐rich Mediterranean soils. Previous pot study in greenhouse found that zeolites mixed with compost significantly improved potassium availability as well as exchangeable potassium capacity in the soils. To further test this finding, a field experiment was conducted using potato – Solanum tuberosum L., desiree cultivar in peat soils of the Hula Valley, Israel. Adhering to the protocol of the greenhouse experiments, the treatments included 5% compost addition with no zeolites, 2% zeolite addition without compost, co‐addition of 5% compost mixed with 2% zeolites and control. We found that compost addition increased significantly the potatoes yield and the number of large tubers; however, the zeolite addition had no impact on yield. Co‐addition of compost and zeolites did not improve total crop yield or number of large tubers compared with compost addition only. The results are consistent with nutrients availability (N, P, K) across the treatments. In a commercialized field using the experiment conditions, the 2% zeolite addition would amount to 18 ton of zeolites per hectare. Hence, we conclude that soil amendment with the tested zeolite might be beneficial to improve soil retention for cationic nutrients (e.g. K+) under high leaching systems such as plant culture in pots, but in the field with high loads of compost, its effect is minor.
¿Qué es primero: desigualdades o inequidades? A propósito del caso de la mortalidad por VIH/ sida en Cali, Colombia (1986-2012)
Authors: Arrivillaga-Quintero Marcela , Pérez-Flórez Mauricio , Borrero-Ramírez Yadira Eugenia , Cecilia-Zea María , Holguín-Ruiz Jorge , Ross Michael W. 
Published: January 2017

<p class="Pa12"><span class="A4"><span>Este estudio tuvo como objetivo analizar la mortalidad por VIH/sida en Cali, Colombia, en el periodo 1986-2012, y a partir de ahí, comprender, desde el punto de vista conceptual, los determinantes sociales relacionados. Se llevó a cabo un estudio observacional, longitudinal, retrospectivo, con un total de 14 192 casos. Se encontró una tendencia creciente de la tasa de mortalidad, en especial a partir del año 1996; en el 2011 se presentó la mayor tasa de todo el periodo. La medición de la desigualdad reveló que se han producido más muertes en estratos medios y bajos, en comparación con el estrato alto. Este estudio aporta evidencia sobre las desigualdades persistentes en la mortalidad por VIH/sida como expresión de inequidades de tipo estructural en la ciudad de Cali. En la perspectiva de Breilh, son procesos críticos de determinación económica y social que pudieron afectar la mortalidad, especialmente de los grupos con más vulnerados socialmente. </span></span></p>
A MATHEMATICAL MODEL OF PANCREATIC CANCER WITH TWO KINDS OF TREATMENTS
Authors: HE DAN-HUA , XU JIAN-XIN 
Published: January 2017

In this paper, we investigate a mathematical model of pancreatic cancer, which extends the existing pancreatic cancer models with regulatory T cells (Tregs) and Treg inhibitory therapy. The model consists of tumor-immune interaction and immune suppression from Tregs. In the absence of treatments, we first characterize the system dynamics by locating equilibrium points and determining stability properties. Next, cytokine induced killer (CIK) immunotherapy is incorporated. Numerical simulations of prognostic results illustrate that the median overall survival associated with treatment can be prolonged approximately from 7 to 13 months, which is consistent with the clinical data. Furthermore, we consider cyclophosphamide (CTX) therapy as well as the combined therapy with CIK and CTX. Intensive simulation results suggest that both CTX therapy and the combined CIK/CTX therapy can reduce the number of Tregs and increase the overall survival (OS), but Tregs and tumor cells will gradually rise to equilibrium state as long as therapies are ceased.
USO DAS ALAVANCAS DE CONTROLE DE SIMONS (1995) NA GESTÃO DE UMA COOPERATIVA AGROINDUSTRIAL
Authors: Pletsch Caroline Sulzbach , Lavarda Carlos Eduardo Facin 
Published: January 2017

O estudo teve como objetivo verificar como as alavancas de controle de Simons (1995) são utilizadas na gestão de uma Cooperativa Agroindustrial. Trata-se de um estudo de caso em uma Cooperativa Agroindustrial, com característica descritiva e qualitativa. Para a coleta de dados se utilizou de entrevistas, documentos e observação. Foi utilizado a análise de conteúdo categorizada por temas, com o auxílio do software Nvivo® e nuvens de palavras para a análise dos dados. Verificou-se que sistemas de diagnóstico (monitoramento das atividades) e sistemas interativos (envolvimento dos gestores, incentivo a aprendizagem organizacional e o surgimento de novas ideias) são os de maior utilização na organização, pois estes são utilizados constantemente e fazem parte do dia a dia da organização objeto do estudo. As crenças não são disseminadas de forma clara e os sistemas de fronteiras são utilizados somente quando existe a necessidade de se estabelecer limites de atuação e comportamentais, não sendo utilizados constantemente.
Simulated Atmospheric Response to Regional and Pan-Arctic Sea Ice Loss
Authors: Screen James A. 
Published: January 2017

Abstract
The loss of Arctic sea ice is already having profound environmental, societal, and ecological impacts locally. A highly uncertain area of scientific research, however, is whether such Arctic change has a tangible effect on weather and climate at lower latitudes. There is emerging evidence that the geographical location of sea ice loss is critically important in determining the large-scale atmospheric circulation response and associated midlatitude impacts. However, such regional dependencies have not been explored in a thorough and systematic manner. To make progress on this issue, this study analyzes ensemble simulations with an atmospheric general circulation model prescribed with sea ice loss separately in nine regions of the Arctic, to elucidate the distinct responses to regional sea ice loss. The results suggest that in some regions, sea ice loss triggers large-scale dynamical responses, whereas in other regions sea ice loss induces only local thermodynamical changes. Sea ice loss in the Barents–Kara Seas is unique in driving a weakening of the stratospheric polar vortex, followed in time by a tropospheric circulation response that resembles the North Atlantic Oscillation. For October–March, the largest spatial-scale responses are driven by sea ice loss in the Barents–Kara Seas and the Sea of Okhotsk; however, different regions assume greater importance in other seasons. The atmosphere responds very differently to regional sea ice losses than to pan-Arctic sea ice loss, and the response to pan-Arctic sea ice loss cannot be obtained by the linear addition of the responses to regional sea ice losses. The results imply that diversity in past studies of the simulated response to Arctic sea ice loss can be partly explained by the different spatial patterns of sea ice loss imposed.
Revised Parameterization of Air–Sea Exchanges in High Winds for Operational Numerical Prediction: Impact on Tropical Cyclone Track, Intensity, and Rapid Intensification
Authors: Ma Yimin , Davidson Noel E. , Xiao Yi , Bao Jian-Wen 
Published: January 2017

Abstract
In high-wind conditions, sea spray, in conjunction with a generally decreasing drag coefficient for increasing winds, greatly modulates surface heat and momentum fluxes. It has been suggested that the process can be particularly important for the prediction of tropical cyclones (TCs), yet its robust application in operational forecast systems has remained elusive. A sea spray inclusion scheme and a modified algorithm for momentum exchange have been implemented in the Australian Bureau of Meteorology’s current operational TC model. Forecasts for a limited sample of TCs demonstrate that the revised parameterizations improve initialized and forecast intensities, while mostly maintaining track prediction skill. TC Yasi (2011) has been studied for impacts of the revised parameterization on rapid intensification (RI). Compared with the conventional bulk air–sea exchange parameterization, the revised version simulates a cooler and moister region near the surface in the eyewall/eye region, adjusts the RI evolution by an earlier and stronger subsidence in the eye, and simulates a stronger radial pulsating of the eye and eyewall convection on relatively short time scales. The inclusion of the new scheme enhances RI features characterized by eyewall ascent, radial convergence, and inertial stability inside the radius of azimuthal-mean maximum wind over low- to midlevels, and by a ringlike radial distribution of relative vorticity above the boundary layer. In addition, it allows a higher maximum intensity wind speed based on Emanuel’s maximum potential intensity theory. It is shown that, as expected, this is mainly because of a larger ratio of enthalpy and momentum exchange coefficients.
Diet quality of individuals with rheumatoid arthritis using the Healthy Eating Index (HEI)-2010
Authors: Berube Lauren Thomas , Kiely Mary , Yazici Yusuf , Woolf Kathleen 
Published: January 2017

Background: Rheumatoid arthritis (RA) afflicts approximately 1.5 million American adults and is a major cause of disability. As disease severity worsens, individuals with RA may experience functional decline that can impact dietary intake. Objective: The objective of this study is to assess the diet quality of individuals with RA using the Healthy Eating Index (HEI)-2010 and examine associations between diet quality and disease activity and functional status. Methods: This cross-sectional study assessed diet quality and disease activity and functional status in adults with RA. Participants completed seven-day weighed food records, which were scored using the HEI-2010. Participants had a fasting blood draw and completed the Multidimensional Health Assessment Questionnaire to determine disease activity and functional status. Results: The mean age of individuals with RA ( N = 84) was 53 ± 14 years, and 86.9% were female. The mean HEI-2010 total score was 58.7 ± 15.9, with 7.1% of participants scoring “good”, 58.3% “fair”, and 34.5% “poor”. Most participants did not adhere to recommended intakes of total fruit, total vegetables, whole grains, fatty acids, refined grains, sodium, and empty calories. An unadjusted multiple linear regression model found duration of morning stiffness and C-reactive protein concentration to be significant variables to inversely predict HEI-2010 total score. Conclusions: The diet quality of many individuals with RA needs improvement and may be related to functional disability associated with RA. Healthcare providers should encourage individuals with RA to meet dietary guidelines and maintain a healthy diet. Moreover, healthcare providers should be aware of the potential impacts of functional disability on diet quality in individuals with RA.
Oncotic pressure and paediatric cardiopulmonary bypass: establishing baseline data for complex congenital cardiac surgery and its relation to risk stratification.
Authors: Crook Richard , Issitt Richard 
Published: January 2017

Objectives: Colloid osmotic pressure (COP) is a major determinant of fluid shift in paediatric patients undergoing corrective surgery for congenital heart disease (CHD) using cardiopulmonary bypass (CPB). However, very few baseline data are available for those patients requiring surgery within the first few weeks and months of life. Our aim was to determine if our CHD population exhibited COP similar to that of other extremely ill subsets of patients and, if so, whether this related to risk stratification model scores. Methods: Thirty consecutive patients under 10 kg underwent cardiac surgery with CPB. Data were collected on COP, albumin concentration, prime composition, post-operative length of ventilation and intensive care unit (ICU) stay as well as risk stratification utilising Risk Adjustment for Congenital Heart Surgery (RACHS-1) and Partial Risk Adjustment in Surgery (PRAiS) scoring systems. Results: The patients had a mean pre-bypass COP of 13.9±2.5 mmHg. A significant negative correlation was observed between pre-operative baseline COP and length of ventilation (r=0.7; p<0.001) and a significant negative correlation between PRAiS (r=0.64; p<0.001) and RACHS-1 (r=0.5; p=0.004) scores and baseline COP was seen. Conclusions: Neonatal and paediatric patients requiring surgical correction of complex congenital cardiac malformations exhibit extremely low baseline COP, comparable to other sick neonatal populations, and are lower than those previously reported. Baseline COP correlates significantly with predicted survival rates and time spent on a ventilator.
“No High Like a Brownie High”: A Content Analysis of Edible Marijuana Tweets
Authors: Cavazos-Rehg Patricia A. , Zewdie Kidist , Krauss Melissa J. , Sowles Shaina J. 
Published: January 2017

Purpose: To investigate tweets about marijuana edibles for surveillance into the content of edibles-related tweets among individuals socially networking about this topic on Twitter. Design: Cross-sectional analysis of tweets containing edible marijuana-related key words during 1 month. Setting: Twitter. Participants: Tweets sent during January 1 to 31, 2015. Methods: A random sample of 5000 tweets containing edibles-related key words was coded for sentiment (positive, negative, and neutral) by crowdsourced workers. Tweets normalizing or promoting edibles use were further analyzed, and demographic characteristics of the Twitter handles sending these tweets were inferred. Results: Of the 5000 tweets, 4166 (83%) were about marijuana edibles, and of those 75% (3134 of 4166) normalized or encouraged edibles use. Nearly half (48%, 1509 of 3134) of the tweets normalizing edibles mentioned wanting or planning to consume, currently consuming, or recently consuming edibles, and 12% (378 of 3134) described the intense or long-lasting effects following use. Individuals whose tweets promoted/encouraged edibles use were more likely to be young (between 17 and 24 years old) and of a racial/ethnic minority (52% black; 12% Hispanic) when compared to the Twitter average. Conclusion: Tweets that normalize edibles use have the potential to increase their popularity. The prevalence of tweets about edibles’ intense high could have implications for tailoring prevention messages that could be important for youth and young adult minorities who were inferred to be disproportionately socially networking about edibles on Twitter.
Expanding Ambulatory Care Pharmacy Residency Education Through a Multisite University-Affiliated Model
Authors: Schweiss Sarah K. , Westberg Sarah M. , Moon Jean Y. , Sorensen Todd D. 
Published: January 2017

Introduction: As the health-care system evolves and shifts to value-based payment systems, there is a recognized need to increase the number of ambulatory care trained pharmacists. Objective: The objective of this article is to describe the administrative structure of the University of Minnesota Postgraduate Year 1 (PGY1) Pharmacy Residency program and to encourage adoption of similar models nationally in order to expand ambulatory care residency training opportunities and meet the demand for pharmacist practitioners. Program Structure: The University of Minnesota PGY1 Pharmacy Residency program is a multisite program centered on the practice of pharmaceutical care and provision of comprehensive medication management (CMM) services in ambulatory care settings. The centralized administration of a multisite academic-affiliated training model creates efficiency in the administration process, while allowing sites to focus on clinical training. This model also offers many innovative and unique opportunities to residents. Conclusion: A multisite university-affiliated ambulatory care residency training model provides efficiency in program administration, while successfully accelerating the growth of quality ambulatory care residency training and supporting innovative delivery of shared core learning experiences. Consequently, practice sites grow in their service delivery capacity and quality of care.
Tablet terminals: a useful tool to explain in vitro fertilization treatment
Authors: Yanaihara Atsushi , Ohgi Shirei , Motomura Kenichirou , Yanaihara Takumi 
Published: January 2017

Abstract
Background
Explanations that involve medical care treatment take time. This also applies to explanations of in vitro fertilization (IVF) in the field of infertility treatment. This is because the cause of infertility differs from couple to couple, and because the explanations must begin with the mechanism of pregnancy. Recently, explanations facilitated by tablet terminals have been used in the field of medicine. In the present study, the efficacy and problems of explanations facilitated by tablet terminals were evaluated and compared with the explanations of IVF facilitated by paper-based pamphlets.

Methods
A total of 249 couples were asked to read a paper-based pamphlet explaining IVF treatment, while 252 couples were asked to view an explanation on a tablet terminal. The patients then answered a seven-item questionnaire. The answers to the questionnaire were based on a three-point scale, and statistical analysis was performed with the Mann-Whitney U test.

Results
Patients responded that the explanation facilitated by the tablet terminal was significantly easier to understand for all seven questionnaire items (p <0.05).
The answer ‘I did not understand’ was selected for the items related to ‘The treatment fees’ (4.8% of answers) and ‘Things to take note of, such as consultation times’ (6.7% of answers).

Conclusion
While patients generally did not understand the mechanism of pregnancy, explanations of IVF treatment facilitated by a tablet terminal were found to be more effective than paper-based explanations, although there is room for improvement.