bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Project Based Learning (PjBL) Model on Science Process Skills and Student Cognitive Learning Outcomes
Authors: Warmadewi Ida Ayu Putu Nova , Subagia I Wayan , Suja I Wayan 
Published: October 2024

This study aims to describe and explain the differences in science process skills and cognitive learning outcomes between students who learn using Project Based Learning (PjBL) and conventional learning in science subjects. This type of research is a quasi-experiment with the matching pretest-posttest control group design. The population in this study is all grade VIII students of SMPN 1 Marga, Tabanan Regency for the 2022/2023 academic year. Research sampling based on class matching techniques. The research instruments are observation sheets of science process skills and cognitive learning outcomes tests. The data in this study is in the form of students' science process skill scores and cognitive learning outcomes scores which are analyzed based on descriptive analysis and the Multivariate Analysis of Covariance (MANCOVA) test. The results showed that: (1) simultaneously there are differences in science process skills and cognitive learning outcomes between students who learn using Project Based Learning (PjBL) and conventional learning in science subjects, (2) there are differences in science process skills between students who learn using Project Based Learning (PjBL) and conventional learning in science subjects, and (3) there are significant differences in cognitive learning outcomes between students who learn using Project Based Learning (PjBL) and conventional learning in science subjects. The group of students who learned using Project Based Learning (PjBL) showed that science process skills and cognitive learning outcomes in science subjects were superior to the group of students who learned with conventional learning.
Morphological Processes in English and Sanskrit: A Cross-Linguistic Study
Authors: Ramnath Neupane  
Published: October 2024

Morphology is the sub-discipline of linguistics. It is the study of morphemes and their arrangement in forming words. The present study attempts to identify and compare the morphological processes in English and Sanskrit. This study was based on qualitative methods and the selected documents of both languages were used as the research tools for this study. The results reveal that the English suffixes such as -age, -al,-ation,-ism, -ment, -ant, -ent, -er, and Sanskrit suffixes such as -ya/-eya, -man, -na, -an, -a, -ti -a, -ana, -ah, -ti, -tri, -aka, -man, are nominal derivational suffixes. The plural morpheme -s, and genitive morpheme -'s are English nominal inflectional morphemes whereas there are twenty-one inflectional suffixes (sup) (su, au, jas) in Sanskrit. Similarly, English verbal inflectional morphemes are -ed, -en, and -ing whereas there are eighteen verbal inflectional suffixes (tin) (tip, tas, jhi,) in Sanskrit. Furthermore, there are compound nouns (breakfast), verbs (fine tune), adjectives (open-ended), and adverbs (uprightly) in English. In contrast, there are only two special sub-class of exocentric compounds in Sanskrit, namely numerative (dvigu), and adverbials (avyayībhāva). As a comparative study, it can help identify the root knowledge of both languages as languages are related to each other.
Percepciones del equipo de atención primaria sobre el enfoque de género aplicado en salud
Authors: Thauby De la Torre Justine , Mazzucchelli Olmedo Nicole , Arévalo Salinas Astrid 
Published: October 2024

Introducción: El enfoque de género aplicado en salud, consiste en reconocer las asimetrías sociales entre géneros como determinantes de los procesos de salud-enfermedad-atención. Este trabajo comparte resultados de una investigación realizada en Chile, sobre las percepciones que el equipo de atención primaria tiene respecto al enfoque de género. Metodología: El estudio siguió un diseño cualitativo aplicando entrevistas a trabajadores de un centro de salud familiar. Luego se realizó un análisis de contenido. Resultados: Se distinguen creencias y valores diferenciados en torno al género, su aplicabilidad en salud, el rol institucional y el impacto en la salud de las mujeres. Discusión: Los participantes vinculan el enfoque de género con la aceptación y respeto hacia todas las personas. Sin embargo, este enfoque coexiste con una normalización respecto a la sobrecarga de las mujeres y su rol en los cuidados de salud, escasa formación del equipo en género y barreras institucionales para su implementación. Conclusiones: Los trabajadores de salud realizan un esfuerzo por autoformarse en género, pero su conocimiento es reducido afectando las prácticas clínicas y la implementación general de este enfoque en la atención primaria. Igualmente se obstaculiza la promoción de la equidad de género en el contexto de atención sanitaria.
Colamine and tartaric acid based innovative antioxidant and anti-spoilage food additive for fish product industry
Authors: Mikaelyan Aram , Soghomonyan Tigran , Babayan Bella , Bagdasaryan Samvel , Asatryan Nona , Grigoryan Anna , Melkumyan Marina 
Published: October 2024

Background: Fish farming is a vital sector of the global food industry, facing the challenge of developing efficient, chemical-free feeds for high-value fish species. To address this, innovative antimicrobials and antioxidants are crucial. This study explores the antioxidant and anti-spoilage properties of novel N-containing derivatives of natural L-tartaric acid (TA), a safe and widely used food additive.
Objectives: Current research is devoted to L-tartrates’ new derivatives’ anti-spoilage and antioxidant potential as an innovative combined feed additive for fish farming.
Results: TA Cyclic imide obtaining modified technology was advised. According to the obtained results, TA itself didn’t show antioxidant activity: nevertheless, in combination with new N-containing derivatives, it increased the antioxidant properties of L-ascorbic acid by about 20%. The studied TA amino-derivatives have demonstrated the emphasized activity against the fish-pathogenic Pseudomonas, Streptococcus, and other pathogenic microbes.
Conclusions: TA and tartrates, in combination with new N-containing derivatives generated based on the vital compound colamine, have demonstrated several synergic antioxidant activities. They can be recommended for potential application as a cheap and effective alternative to classical anti-spoilage and preservative agents for animal feed production. Also, they showed the prolongation of feed expiration periods. It will significantly increase the quality of final fish products. A further detailed study of toxicological properties of amino derivatives is planned.
Keywords: tartaric acid derivative, colamine, antimicrobial, antioxidant, anti-spoilage, feed additive
<i>Movement Behavior and Physical Fitness </i>di Sekolah Menengah Pertama Berbasis Negeri Se-Kecamatan Lowokwaru Kota Malang
Authors: Kanduwi Exy , Fitriady Gema , Darmawan Arief 
Published: October 2024

Movement Behavior mengacu pada jenis-jenis aktivitas fisik yang dilakukan seseorang, termasuk pada FITT (Frequency, Intensity, Type and Time) Hal ini perilaku ferak sangat memepengaruhi kebugaran jasmani pada seseorang. Penelitian ini bertujuan untuk melihat periaku gerak dan kebugaran jasmani peserta didik Sekolah Menengah Pertama Negeri di Kecamatan Lowokwaru. Metode penelitian ini adalah survei dengan teknik pengambilan sampel purposive proportional sampling melibatkan 317 siswa yang terinci dari 155 putra dan 162 putri pada SMP Negeri kelas VIII di Kecamatan Lowokwaru, Kota Malang. Instrumen yang digunakan adalah Tes Kebugaran Jasmani Indonesia dan kuesioner aktivitas fisik. Hasil penelitian yang diperoleh peserta didik mempunyai rata rata terbesar pada kategori sedang dengan persentase 43,9% putra dan 45,7% Putri. Temuan baru penelitian ini peserta didik melakukan aktivitas fisik dengan intensitas sedang hingga tinggi, namun frekuensinya kurang dari 3 kali dalam seminggu dan durasinya kurang dari 60 menit. Hal ini tidak sesuai dengan pedoman yang disarankan oleh WHO yang merekomendasikan aktivitas fisik minimal 3 kali dalam seminggu dengan durasi >60 menit untuk mencapai kebugaran jasmani yang optimal
Olhar Psicopedagógico aos Fatores que Dificultam a Aprendizagem dos Estudantes da Escola Superior Pedagógica do Bengo
Authors: Morales Victor João 
Published: October 2024

O presente artigo, resultante de um estudo realizado durante o 1.º semestre do ano académico 2022-2023, visa identificar os fatores que dificultam a aprendizagem dos estudantes da Escola Superior Pedagógica do Bengo. Trata-se de um estudo de caso de caráter exploratório, pressupondo que os resultados obtidos com esta pesquisa não são generalizáveis. A pesquisa enquadra-se no modelo qualitativo, tendo na base opinião de sujeitos que agem em determinado contexto, influenciados por condicionantes sociais, econômicas, políticas e culturais e como técnica de recolha de dados a entrevista semiestruturada, a qual possibilitou fazer adequações ao longo de sua aplicação sempre que necessário. Com efeito, os dados obtidos por meio de gravações foram transcritos manualmente e codificados frase por frase, gerando um total de 233 códigos agrupados em 4 categorias de análise. Em termos de participantes, um número de 36 estudantes constitui a amostra do estudo, representando os cursos que são ministrados naquela instituição de ensino, quais sejam: Ensino da Psicologia, Ensino da Pedagogia, Ensino da Língua Portuguesa, Ensino da História, Ensino da Matemática e Ensino da Informática. Consequentemente, os resultados revelam que diversos fatores dificultam a aprendizagem desses estudantes, com maior incidência nas relações interpessoais entre professores e alunos, sem descartar os fatores pedagógicos, socioeconômicos e fatores pessoais. Em decorrência disso, a conceção de projeto ou ações psicopedagógicas voltadas aos intervenientes da instituição, com maior realce aos professores e estudantes, ajudaria a mitigar consideravelmente os problemas identificados e a promover vias mais adequadas no desenvolvimento do processo de ensino-aprendizagem, tendo em conta as caraterísticas dos estudantes e os desafios que enfrentam no seu dia-a-dia. Contudo, não é pretensão da presente pesquisa encerrar essa temática tão delicada, porém espera estimular o desenvolvimento de outras pesquisas, sobretudo do âmbito experimental e de natureza estatística, a fim de aprofundar a exploração de situações latentes que atentam a qualidade do processo de ensino-aprendizagem no seio da Escola Superior Pedagógica do Bengo.
Resistive Embodiment and Incestuous Desire in Mary Shelley’s Mathilda
Authors: Veronie Crystal 
Published: October 2024

This essay introduces ‘resistive embodiment’ as a keyword for critical examination of strategies of writing in Mary Shelley’s novel Mathilda. Strategies of writing in the novel parallel similar discourse in women’s writing of the era, whereby bodies are variously depicted as resisting the masculine gaze. In the case of Mathilda, the heroine’s body is shown as thwarting her father’s unnatural desires by short-circuiting feminine passivity. Contrary to social expectations, Matilda’s body revolts ‘with winged speed’ and frees her from her father’s control. In addition, strategies of writing imply that the illness that follows this encounter and which eventually claims Matilda’s life is rooted in a complex co-operative relationship between Matilda’s desires and her body’s responses. Through its exploration of physiological responses to the imagined taint of her father’s transgressive desire, Mathilda offers key insights into Shelley’s views on the transgressive nature of erotic desire and reflects the guarded position of women at the moment at which bodies had come under increasing medical surveillance.
Hong Kong Crime Films
Authors: Van den Troost Kristof 
Published: October 2024

This book details the post-war history of the Hong Kong crime film up to the release of John Woo’s A Better Tomorrow (1986), the film that put the genre on the map globally. It coins the term “criminal realism” to not only describe the brand of realism one finds in crime films, but also to highlight how depictions of Hong Kong’s social reality (including crime) were for decades anxiously policed by colonial censors—in other words, how realism was often literally “criminal” (or illegal). In a cultural and intellectual environment that highly valued “realism” as progressive and modern, “criminal realism” in addition refers to a realism that was, due to its unabashedly commercial and sensationalist character, illegitimate in the eyes of most local critics. To make these arguments, the book draws extensively on government and other archives. The result is more than just a genre history of the Hong Kong crime film; it also is also a close study of the impact of censorship on a popular cinema.
John Middleton Murry’s Unfinished Second Volume of Autobiography
Authors: Ferrall Charles 
Published: October 2024

Parts of John Middleton Murry's unpublished 1947 sequel to his autobiography Between Two Worlds are well known to Mansfield scholars through F.A. Lea's extensive quotation from them in his biography of Murry. But the original manuscript held at the Turnbull Library in Wellington appears to have been unknown to scholars until now. The section reproduced here concerns the death of Katherine Mansfield and the "possession" by Mansfield of Murry's second wife, Violet Le Maistre.
rhBMP-2-loaded hydroxyapatite/beta-tricalcium phosphate microsphere/hydrogel composite promotes bone regeneration in a novel rat femoral nonunion model
Authors: Kitahara Takayuki , Tateiwa Daisuke , Hirai Hiromasa , Ikuta Masato , Furuichi Takuya , Bun Masayuki , Ukon Yuichiro , Kanie Yuya , Furuya Masayuki , Fujimori Takahito , Okada Seiji , Kaito Takashi 
Published: October 2024

BackgroundNonunion following fracture treatment remains a significant clinical challenge, adversely affecting the patient’s quality of life and imposing a substantial economic burden. The emergence of bone morphogenetic protein 2 (BMP-2) for bone regeneration represents a promising avenue, albeit limited by side effects such as inflammatory reactions primarily due to suboptimal drug delivery systems. This study focuses on NOVOSIS putty (NP), a novel biomaterial designed for the sustained release of BMP-2, aiming to mitigate these limitations and enhance bone healing.ObjectiveThis research aimed to evaluate the effectiveness of NP, a hydroxyapatite granules/β-tricalcium phosphate hydrogel composite (HA/β-TCP/hydrogel), as a BMP-2 carrier for promoting bone regeneration in a new rat nonunion model of long bone.MethodsUsing Sprague Dawley rats, a 2-mm silicone disk was interposed at the femoral fracture site, and intramedullary fixation with K-wire was performed to create a nonunion with a 2-mm bone defect. After 3 weeks, internal fixation with a plate, removal of the silicon disk, and refreshing the nonunion site were performed by implanting three different materials into the nonunion sites: allogenic iliac bone (IB), collagen sponge (CS) containing 10 μg of BMP-2, or NP containing 10 μg of BMP-2. Bone healing was evaluated weekly using micro-computed tomography (CT); ex vivo micro-Ct and histological evaluation were conducted at 6 weeks.ResultsAt 6 weeks, NP demonstrated a significantly higher bone union rate (76.5%) compared with the CS group (35.3%, p = 0.037), and the IB group (6.3%, p &lt; 0.0001). Bone mineral density (BMD) and bone volume/tissue volume (BV/TV) were also significantly higher in the NP group compared with the CS group (BMD, p &lt; 0.0001; BV/TV, p = 0.031). Histological analysis showed the fracture gap in the NP group was filled with more trabecular bone and less fibrous tissue compared with the CS group.ConclusionThe study confirms NP is a highly effective BMP-2 carrier, significantly improving bone union rates and new bone formation in nonunion fractures. The sustained release of BMP-2 from the hydrogel component reduced inflammatory responses and enhanced bone regeneration. NP can be a promising alternative to collagen-based BMP-2 delivery systems.
The RNA m5C methyltransferase NSUN1 modulates human malaria gene expression during intraerythrocytic development
Authors: Tang Ruoyu , Fan Yanting , Lu BinBin , Jiang Qunfeng , Cheng Xinyu , Zhang Zuping , Shen Li , Shang Xiaomin 
Published: October 2024

IntroductionPlasmodium falciparum is the most damaging malaria pathogen and brings a heavy burden to global health. Host switching and morphological changes in P. falciparum are dependent on an effective gene expression regulatory system. C5 methylation of cytosines is a common RNA modification in eukaryotes, and the NSUN family are essential m5C modification executors. Currently, little is known about this family in Plasmodium spp. In this study, we focus on exploring the function of PfNSUN1 protein.MethodsAn efficient CRISPR/Cas9 gene editing technique was applied to construct the PfNSUN1 knockdown strain. The knockdown efficiency was confirmed by growth curves and western blot experiments. The knockdown transcriptome data was acquired to find differentially expressed genes, and target genes of PfNSUN1 protein were identified by RNA immunoprecipitation and high-throughput sequencing experiments.ResultsThe efficiency of PfNSUN1 protein down-regulated was about 34%. RNA-seq data revealed that differentially expressed genes were mainly down-regulated. And there were 224, 278, 556 genes that were down-regulated with more than 2-fold changes and p-adj&lt;0.05 at ring, trophozoite and schizont stages, respectively. PfNSUN1 protein was significantly enriched on 154 target genes, including 28S ribosomal RNA and pfap2-g5 transcription factor.DiscussionPfNSUN1 is a crucial RNA post-transcriptional modification protein in P. falciparum. It plays a pivotal role in regulating gene expression and parasite growth by targeting 28S ribosomal RNA and pfap2-g5 transcription factor.
Microclimate monitoring in commercial tomato (Solanum Lycopersicum L.) greenhouse production and its effect on plant growth, yield and fruit quality
Authors: Šalagovič Jakub , Vanhees Dorien , Verboven Pieter , Holsteens Kristof , Verlinden Bert , Huysmans Marlies , Van de Poel Bram , Nicolaï Bart 
Published: October 2024

IntroductionHigh annual tomato yields are achieved using high-tech greenhouse production systems. Large greenhouses typically rely only on one central weather station per compartment to steer their internal climate, ignoring possible microclimate conditions within the greenhouse itself.MethodsIn this study, we analysed spatial variation in temperature and vapour pressure deficit in a commercial tomato greenhouse setting for three consecutive years. Multiple sensors were placed within the crop canopy, which revealed microclimate gradients.Results and discussionDifferent microclimates were present throughout the year, with seasonal (spring – summer – autumn) and diurnal (day – night) variations in temperature (up to 3 °C, daily average) and vapour pressure deficit (up to 0.6 kPa, daily average). The microclimate effects influenced in part the variation in plant and fruit growth rate and fruit yield – maximum recorded difference between two locations with different microclimates was 0.4 cm d-1 for stem growth rate, 0.6 g d-1 for fruit growth rate, 80 g for truss mass at harvest. The local microclimate effect on plant growth was always larger than the bulk climate variation measured by a central sensor, as commonly done in commercial greenhouses. Quality attributes of harvested tomato fruit did not show a significant difference between different microclimate conditions. In conclusion, we showed that even small, naturally occurring, differences in local environment conditions within a greenhouse may influence the rate of plant and fruit growth. These findings could encourage the sector to deploy larger sensor networks for optimal greenhouse climate control. A sensor grid covering the whole area of the greenhouse is a necessity for climate control strategies to mitigate suboptimal conditions.
Brugia malayi filarial helminth-derived extracellular vesicles suppress antigen presenting cell function and antigen-specific CD4+ T cell responses
Authors: Sanku Gayatri , Ricciardi Alessandra , Redekar Neelam R. , Schaughency Paul , Lack Justin , Gazzinelli-Guimaraes Pedro H. , Nutman Thomas B. 
Published: October 2024

IntroductionLive microfilariae (mf) and mf-derived extracellular vesicles (EVs) have been shown to modulate human antigen presenting cell (APC) function, most notably by suppressing the induction of IL-12 (and other pro-inflammatory cytokines) following activation with LPS and interferon-y. MethodsTo explore further how EVs alter human APC function, we studied the effect of mf and EVs on human elutriated monocyte-derived dendritic cells (DC) following exposure to Mf, mf-derived excretory/secretory (E/S) products, E/S depleted of EVs through ultracentrifugation and purified EVs. After demonstrating that the measurable responses induced by live mf could be recapitulated by EVs and EV-containing E/S, we next performed RNAseq analysis of human DC following exposure to live mf, EVs, E/S, or EV-depleted E/S. ResultsIn our analyses of the data for the DC, using a false discovery rate (FDR)&lt;0.05, EV-exposed DC had induced the expression of 212 differentially expressed genes (DEGs) when compared to unexposed DC and 157 when compared to E/S-depleted EVs. These genes were enriched in GO biological processes associated with neutrophil degranulation and 15 DEGs associated with KEGG Lysosome pathways. IPA analysis point to immune dysregulation. We next aimed to understand the intracellular processes altered by EVs and the effect these have on effector T cells. When SARS CoV-2 Membrane-specific CD4+ TCLs were assessed following EV conditioning of autologous DC and activation with the SARS CoV-2-Membrane peptide pool, we found conditioning reduced the frequency of SARS CoV-2 Membrane-specific CD3+ CD4+ CD154+ cells (p=.015). Similarly, EV-conditioning of SARS CoV-2 Membrane-specific CD3+ CD4+ cells induced fewer cell capable of producing IFN-γ (p=.045). DiscussionTaken together, our data suggest a modulatory role of EVs on APC function that likely leads to defects in T cell effector function.