bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the Ecstasy influence on tramadol and its main metabolite plasma concentration in rats
Authors: Jamali Bardia , Sheikholeslami Behjat , Hosseinzadeh Ardakani Yalda , Lavasani Hoda , Rouini Mohammad-Reza 
Published: September 2017

AbstractBackground:Tramadol is prone to be abused alone, or in combination with 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy). It was reported that 95% of people with a history of substance abuse in the United States used tramadol in 2004. According to the WHO report in 2016, there was a growing number of tramadol abusers alone or in combination with psychoactive substances such as MDMA in particular in some Middle East countries. Higher concentrations of tramadol in plasma may lead to adverse drug reactions or lethal intoxication. In this study, the effect of MDMA on the pharmacokinetics of tramadol was examined in male rats.Methods:The effect of MDMA on TResults:When tramadol administered intraperitoneally, the absorption rate of this drug was reduced, and a lower CConclusions:According to the obtained data, MDMA treatment affected the absorption, distribution and metabolism phases of tramadol. This treatment increased the concentration of tramadol if administered intravenously and can latent the absorption of tramadol in oral route. However, MDMA was introduced as CYP2D6 inhibitor; in this study, MDMA inhibited CYP3A4 isoenzymes as well. This finding is important for the compounds that are metabolized through CYP3A4. It can be proposed that in abusers of MDMA who only receive tramadol for medical or nonmedical purposes in short intervals, the dangers of the intravenous administration of tramadol should be considered, and if tramadol is administered orally, the desired effect may not be achieved at the routine dose.
Distribution of P2O5 between P-rich Phase and Matrix Phase in P-bearing Steelmaking Slag
Authors: Lin Lu , Bao Yan-ping , Gu Chao , Wu Wei , Zeng Jia-qing 
Published: September 2017

AbstractTo recycle the phosphorus in P-bearing steelmaking slag and use the slag as phosphate fertilizer, it is necessary to study the distribution of P2O5 between the P-rich phase and matrix phase in P-bearing steelmaking slag. The addition of MgO and MnO into the slag has no effect on the phosphorus form of existence in the slag and has little effect on the %(P2O5)SS. In contrast, Na2O and CaF2 in the slag change the phosphorus form of existence in the slag and increase %(P2O5)SS obviously. Lp’, ${\gamma _{{{\rm{P}}_2}{{\rm{O}}_5}(SS)}}$, ${\gamma _{{{\rm{P}}_2}{{\rm{O}}_5}(M)}}$, CP(M) and CP(SS) were calculated, and it was found that %(CaO), %(T.Fe) and %(P2O5) in the P-rich phase and matrix phase significantly affect Lp’. MnO and MgO in the slag have little effect on the distribution of P2O5 between the P-rich phase and matrix phase, whereas Na2O and CaF2 affect the distribution of P2O5 between the P-rich phase and matrix phase.
Stability Analysis of HIV/AIDS Transmission with Treatment and Role of Female Sex Workers
Authors: Rani Pratibha , Jain Divya , Saxena Vinod Prakash 
Published: September 2017

Abstract
This paper concentrates on the role of prostitutes in HIV/AIDS disease transmission among common population. In this communication, a nonlinear Susceptible-Infected-Treated-AIDS infected (SITA) model is developed to study the transmission dynamics of HIV/AIDS infection in three different classes. The behavior of the model is analyzed by the basic reproduction number R
0 and the results of the model are investigated by using stability theory of differential equations. Analysis of the model demonstrates that the disease-free equilibrium is locally stable for

R
0

<

1

${R_0}\, \lt \,1$

and at

R
0

>

1
,

${R_0} \gt \,1, \,$

the endemic equilibrium is globally stable. Further, numerical simulation of the model is carried out.
Rosenau-KdV Equation Coupling with the Rosenau-RLW Equation: Conservation Laws and Exact Solutions
Authors: Muatjetjeja Ben , Rashid Adem Abdullahi 
Published: September 2017

Abstract
We compute the conservation laws for the Rosenau-Kortweg de Vries equation coupling with the Regularized Long-Wave equation using Noether’s approach through a remarkable method of increasing the order of the Rosenau-KdV-RLW equation. Furthermore, exact solutions for the Rosenau- KdV-RLW equation are acquired by employing the Kudryashov method.
A multimodal approach to investigating temporality expression in L2: What does gesture analysis reveal?
Authors: Saddour Inès 
Published: September 2017

AbstractResearch on temporality expression has had a prolific history within second language acquisition (SLA) research and has provided a clear picture of temporal and aspectual (henceforth Tem) markers and their order of emergence and development in L2 acquisition. However, most of the studies have only examined speech and neglected the gestural modality. This study is an attempt to fill this gap and contribute to the relatively recent investigation of L2 gestures; examining with a combinative approach Tem devices in speech and the gestures produced concomitantly with those linguistic markers in longitudinal video-recorded narratives produced by four low-proficiency tutored French second language (L2) learners. Our results suggest that speech and gesture form an interconnected system and that gestures play a function in dealing with the abstract domain of temporal reference in early SLA. Analyses reveal that L2 learners do not gesture randomly when expressing Tem values. Their gestures co-occurring with different types of Tem linguistic devices are generally different in proportion, duration and type. Gestures are more frequent in non-finite uninflected verbal contexts. Additionally, they are often iconic and last longer on average than those produced simultaneously with verbal morphology or with adverbials. Differences in gesture rate, duration and nature in the different marking contexts and over the data collection period of 5 months suggest that gesturing may help to reduce the cognitive load brought about by the complexity of morphological marking, and may therefore be used strategically to handle hesitant Tem devices in speech in early SLA.
The Contribution of Marketing and Branding Efforts in Food Exports: Evidence from Panel Data
Authors: Drivas Kyriakos 
Published: September 2017

Abstract
This paper examines the relationship between food-related trademark activity, approximating for branding and marketing efforts, and food exports for the 48 contiguous states of the US over the period 1999–2015. We find a strong and positive relationship between these two variables. Further robustness checks, including an instrumental variables approach, provide evidence that marketing and branding activities contribute to food exports. With respect to food export policy our results point to providing incentives to the private sector (cooperatives, farmers, firms) to pursue marketing and branding efforts.
Congruence analysis of geodetic networks – hypothesis tests versus model selection by information criteria
Authors: Lehmann Rüdiger , Lösler Michael 
Published: September 2017

Abstract
Geodetic deformation analysis can be interpreted as a model selection problem. The null model indicates that no deformation has occurred. It is opposed to a number of alternative models, which stipulate different deformation patterns. A common way to select the right model is the usage of a statistical hypothesis test. However, since we have to test a series of deformation patterns, this must be a multiple test. As an alternative solution for the test problem, we propose the p-value approach. Another approach arises from information theory. Here, the Akaike information criterion (AIC) or some alternative is used to select an appropriate model for a given set of observations. Both approaches are discussed and applied to two test scenarios: A synthetic levelling network and the Delft test data set.
It is demonstrated that they work but behave differently, sometimes even producing different results. Hypothesis tests are well-established in geodesy, but may suffer from an unfavourable choice of the decision error rates. The multiple test also suffers from statistical dependencies between the test statistics, which are neglected. Both problems are overcome by applying information criterions like AIC.
Protective effect of salusin-α and salusin-β against ethanol-induced gastric ulcer in rats
Authors: Tanyeli Ayhan , Eraslan Ersen , Polat Elif , Bal Tuğba 
Published: September 2017

Abstract

Background:
Alcohol consumption has been found to be associated with gastric ulcers, including gastric mucosal lesions. Salusin-α and salusin-β are bioactive peptides having 28 and 20 amino acids, respectively. Salusin-α and salusin-β immunoreactivity has been detected in the stomach and in the intestines. It has been reported that the salusins regulate the cytokine levels and decrease the infarct area in the heart tissue after ischemia. In this study, we investigated the effects of the salusins in the gastric injury formed with ethanol.

Methods:
Thirty-two sprague Dawley male rats were randomly divided into four groups, including eight rats in each group as follows: Group 1: control; Group 2: ethanol 5 mL/kg; Group 3: ethanol 5 mL/kg+5 nmol/kg salusin-α; Group 4: ethanol 5 mL/kg+5 nmol/kg salusin-β.

Results:
The salusin-α level increased at a significant level in the ulcer group formed with ethanol (p<0.001); the change in the salusin-β level is not significant. As for malondialdehyde (p<0.05) and myeloperoxidase (p<0.001), when compared with the control group, tumor necrosis factor-α (p<0.05) levels increased in the group to which ethanol was applied and decreased significantly with the application of salusins. Levels of GSH and IL-1β did not change at a significant level. In addition, histopathologic analysis demonstrated that, in salusin-administered groups, mucosal injury and caspase-3 expressions were reduced.

Conclusions:
The suppression of salusin-α and salusin-β on caspase-3 expression by means of their effects on oxidative injury and TNF-α levels shows that these two hormones could serve as anti-ulcerative agents.
Effects of single or combined administration of salmon calcitonin and omega-3 fatty acids vs. diclofenac sodium in sodium monoiodoacetate-induced knee osteoarthritis in male Wistar rats
Authors: Adeyemi Wale J. , Olayaki Luqman A. 
Published: September 2017

Abstract

Background:
There is a continuous search for a better therapy in osteoarthritis (OA) management. Therefore, this study investigated the effects of salmon calcitonin (Sct) and/or omega-3 fatty acids (N-3) relative to diclofenac sodium (DF) in induced knee osteoarthritic male Wistar rats.

Methods:
The 40 rats that were used in this study were divided into 8 groups (n=5 rats), viz: Normal control; OA control; OA+N-3; OA+Low dose of Sct (Sct.Lw); OA+High dose of Sct (Sct.Hi); OA+N-3+SCt.Lw; OA+N-3+Sct.Hi; and, OA+DF. OA was induced with 4 mg of sodium monoiodoacetate in 40 μL of saline. The solution was injected into the left knee joint space of anaesthetised rats. Sct was administered at 2.5 and 5.0 IU/kg b.w. (im), whereas N-3 and DF were administered at 200 and 1 mg/kg b.w. (p.o.), respectively. Treatments commenced 9 days after the induction of OA, and they lasted for 28 days.

Results:
Sct and/or N-3 significantly reduced c-telopeptide of type 1 collagen (CTX-1), collagen type 2 α-1 (C2M), malondialdehyde (MDA), uric acid (UA), and interleukin-6 (IL-6), but, significantly increased superoxide dismutase (SOD) after OA induction. Both therapies had additive effects on C2M, MDA, SOD, and catalase (CAT), but, non-additive actions on UA, IL-6, and CTX-1. Like the Sct and N-3, DF significantly reduced CTX-1, C2M, UA, and IL-6. However, it had no significant effect on SOD and MDA, even though it significantly reduced CAT activity. None of the therapies had significant effect on total alkaline phosphatase activity, except N-3+Sct.Lw.

Conclusions:
The combined, and sometimes the single administration of Sct and N-3 proved to be better therapies in OA management than DF.
Evaluation of neurodevelopment of children with congenital hypothyroidism by the Denver Developmental Screening Test
Authors: Buluş Ayşe Derya , Tiftik Esra 
Published: September 2017

AbstractBackground:Thyroid hormones are essential for growth and brain development in childhood. Although congenital hypothyroidism (CH) is the most common reason for mental retardation, normal neurological development can be achieved through early and effective treatment. The aim of the present study was to evaluate the neurological development of CH patients aged 24–56 months.Methods:The study included a total of 116 healthy control subjects and 112 patients aged 24–56 months who were diagnosed with CH during the neonatal period and were being followed up at the Pediatric Endocrinology Department, Keçiören Training and Research Hospital, between 2012 and 2015. Demographics and clinical data of interventions and outcomes were retrieved for each patient. Statistical analysis was performed using an unpaired Student’s t-test to compare means and χResults:There were no significant differences between the CH and control groups with respect to gestational age, birth weight, height standard deviation scores (HSDS) and body weight standard deviation scores (BWSDS) (p>0.05). When the groups were compared according to the Denver Developmental Screening Test (DDST), no significant differences were found in terms of personal-social, fine motor skills, or language development (p=0.325, p=0.087 and p=0.636, respectively). However, a significant difference was found between the two groups with respect to gross motor development and the result of the DDST (p=0.001). No statistical difference was found between the control and patient groups on the day of starting treatment but the number of patients with an abnormal result in the DDST starting treatment at >15 days was found to be significantly higher than the number of patients starting treatment ≤15 days. No associations were found between the DDST results of the CH group and the following factors: initial L-thyroxine (LT4) level, initial LT4 dose and the onset of treatment.Conclusions:The findings of this study indicate that the DDST results in patients with CH are generally good. Initiating treatment immediately after diagnosis and during the first days of life is absolutely imperative. However, in contrast to timing, we could not find strong evidence for determining the precise optimal dosage of LT4 to initiate treatment in children diagnosed with CH. Both the American Academy of Pediatrics and the European Society for Pediatric Endocrinology recommend 10–15 μg/kg/day as the initial dose.
A retrospective review of initial bisphosphonate infusion in an inpatient vs. outpatient setting for bisphosphonate naïve patients
Authors: Kreikemeier Rose M. , Gosnell Heather , Halbur Lisa M. , Rush Eric T. 
Published: September 2017

AbstractBackground:The purpose of this study was to evaluate the safety and convenience of initial bisphosphonate infusion therapy in inpatient and outpatient settings for patients with low bone mineral density.Methods:All data were collected from retrospective chart reviews of heterogeneous groups of patients. Abnormal findings prior to the infusion and side effects during the infusion were documented. Patients were contacted following the infusion to discuss post-infusion adverse events.Results:The majority of both outpatients (80%, n=44) and inpatients (50%, n=27) did not experience any adverse events related to the infusion. Some patients reported minor adverse events that were expected. Only one of the inpatients had a severe adverse event (SAE) after the infusion.Conclusions:For patients at low risk for severe reactions to treatment, the infusion center appears to be a safe and possibly more convenient treatment setting for both the patient and the hospital, although more expensive for the patient at our institution.
Students’ Academic and Social Transition to New Graduate Programs in Physical Education Teacher Education
Authors: Sato Takahiro , Kozub Francis M. , Samalot-Rivera Amaury 
Published: September 2017

Abstract
The purpose of this study is to describe and explain master students’ academic and social experiences during the transition to teacher education master programs. This study is based on the theory of transition that supports the understanding of students’ transition to graduate studies as they connect to the academic supports needed to cope with the demands of advanced training in physical education. The participants were eight teacher education master students from two institutions who participated in a descriptive-qualitative design. The data sources were a demographic questionnaire, face-to-face interviews, and the program of graduate study. Results in themes related to (a) competing agendas, (b) hesitant to ask for help from professors, and (c) time management shock. To better support teacher education graduate students, we encourage academic departments, administrators, faculty, and all students to learn how to view themselves as playing various roles, such as academic advisors and graduate students.
Crystal structure of bis(3-(3-ethylureido)-N,N-dimethylpropan-1-aminium) bis (μ
3-2-(hydroxymethyl)-2-(oxidomethyl)propane-1,3-bis(olato))-(μ
6-oxo)-hexakis(μ
2-oxo)-hexaoxo-hexavanadium(V) – dichloromethane (1/1), C27H60Cl2N6O23V6
Authors: Hu Xiaokang , Huang Bo , Xiao Zicheng , Wu Pingfan 
Published: September 2017

Abstract
C27H60Cl2N6O23V6, C2/c (no. 15), a = 26.1482(12) Å, b = 10.6096(4) Å, c = 17.4426(6) Å, β = 90.932(4)°, V = 4838.3(3) Å3, Z = 4, R
gt(F) = 0.0565, wR
ref(F
2) = 0.1477, T = 106 K.
Crystal structure of bis(μ3-methanolato-κ3
O:O:O)-bis(μ2-methanolato-κ2
O:O)-dimethanol-bis{6,6′-(1,3-dihydroxyl-2-acetylpropane-1,3-diyl)bis(2-chloro-4-bromophenolato)}tetramanganese(III) C40H40Br4Cl4Mn4O16
Authors: Zhao Ji-Xing , Zhao Li , Wang Fei , An Qin-Qin , Li Peng-Peng 
Published: September 2017

Abstract
C40H40Br4Cl4Mn4O16, triclinic, P1̄, a = 9.3724(9) Å, b = 11.7867(16) Å, c = 12.3994(18) Å, α = 70.650(13)°, β = 75.462(10)°, γ = 81.085(10)°, V = 1247.1(3) Å3, Z = 1, R
gt(F) = 0.0618, wR
ref(F
2) = 0.1201, T = 294 K.
Synthesis and crystal structure tetrakis(μ2-methanolato)-dimethanol-bis(μ2-2-acetyl-1,3-bis(3,5-dichloro-2-oxidophenyl)propane-1,3-bis(olato)-κ5
O
1,O
2,O
3:O
3,O
4,O
5), tetramanganese(III), C40H40Cl8Mn4O16
Authors: Zhao Ji-Xing , Zhao Li , Li Peng-Peng , Zhu Zhao-Bin , Wang Fei , An Qin-Qin 
Published: September 2017

Abstract
C40H40Cl8Mn4O16, triclinic, P1̅, a = 9.2586(5) Å, b = 11.6798(10) Å, c = 12.3267(8) Å, α = 70.237(7)°, β = 75.557(5)°, γ = 81.358(6)°, V = 1211.65(16) Å3, Z = 1, R
gt(F) = 0.0333, wR
ref(F
2) = 0.0906, T = 294 K.
Crystal structure of bis(μ2-acetato-κ2
O:O′)-bis{μ2-4-chloro-2-(8-(4-(diethylamino)-2-oxidophenyl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl)phenolato-κ6
O:O,N,N′,O′′:O′′}tricobalt(II), C44H49Cl2Co3N6O12
Authors: Yang Yu-Hua , Wang Bao-Jun , Lan Peng-Fei , Dong Wen-Kui 
Published: September 2017

Abstract
C44H49Cl2Co3N6O12, Triclinic, P1̅, a = 9.7415(9) Å, b = 13.6440(14) Å, c = 17.5241(11) Å, α = 72.807(10)°, β = 83.019(9)°, γ = 72.246(9)°, V = 2450.6(5) Å3, Z = 2, R
gt(F) = 0.0700, wR
ref(F
2) = 0.1505, T = 291(2) K.
Crystal structure of bis{5-(N,N′-diethylamine)-5′-methoxy -2,2′-[ethylenediyldioxybis(nitrilomethylidyne)]diphenolato}-bis(μ2-acetato-κ2
O:O′)trizinc(II), C46H56Zn3N6O14
Authors: Dong Xiu-Yan , Zhang Han , Wang Bai-Jun , Lan Peng-Fei , Dong Wen-Kui 
Published: September 2017

Abstract
C46H56Zn3N6O14, monoclinic, C2/c (no. 15), a = 10.6703(7) Å, b = 27.091(4) Å, c = 17.9132(16) Å, β = 96.246(8)°, V = 5147.4(10) Å3, Z = 4, R
gt(F) = 0.0647, wR
ref(F
2) = 0.1865, T = 291(1) K.
Crystal structure of (E)-5-(diethylamino)-2-(((1,1,2-trihydroxyethyl)iminio)methyl)phenolate, C15H24N2O4
Authors: Yuan Lin , Li Zhong-Yan , Yuan Xian-You , Zhang Min 
Published: September 2017

Abstract
C15H24N2O4, orthorhombic, Pca21, a = 18.528(6) Å, b = 8.123(2) Å, c = 20.797(6) Å, V = 3129.9(16) Å3, Z = 8, R
gt(F) = 0.0396, wR
ref(F
2) = 0.1082, T = 296(2) K.
A single crystal study on 2-(methylcarbamoyl)benzoic acid, C9H9NO3
Authors: Wei Pengfei , Yang Xiao-Li , Wang Kun-Yan 
Published: September 2017

Abstract
C9H9NO3, monoclinic, P21/c (no. 14), a = 8.7201(8) Å, b = 8.6453(9) Å, c = 11.8083(9) Å, β = 100.830(3)°, V = 874.35(14) Å3, Z = 4, R
gt(F) = 0.0489, wR
ref(F
2) = 0.1142, T = 296(2) K.
Crystal structure of fac-(acetylacetonato-κ2
O,O′)tricarbonyl(benzyldiphenylphosphine-κP)rhenium(I), C27H24O5PRe
Authors: Manicum Amanda-Lee , Alexander Orbett , Schutte-Smith Marietjie , Visser Hendrik G. , Roodt Andreas 
Published: September 2017

Abstract
C27H24O5PRe, triclinic, P1̄ (no. 2), a = 9.0305(17) Å, b = 12.084(2) Å, c = 12.403(2) Å, α = 89.688(6)°, β = 70.083(6)°, γ = 76.315(6)°, V = 1232.2(4) Å3, Z = 2, R
gt(F) = 0.0180, wR
ref(F
2) = 0.0432, T = 100(2) K.
Crystal structure of poly[aqua-(μ3-4-(pyridin-4-yl)isophthalato-κ4
O,O′:O′′:O′′′)-(μ2-5-carboxy-2-(pyridin-4-yl)benzoato-κ2
O:O′)yttrium(III)], C26H17N2O9Y
Authors: Duan Ying , Zang Jia 
Published: September 2017

Abstract
C26H17N2O9Y, monoclinic, P21/n (no. 14), a = 8.9349(7) Å, b = 9.3488(12) Å, c = 28.1854(18) Å, β = 95.061(7)°, V = 2345.2(4) Å3, Z = 4, R
gt(F) = 0.0496, wR
ref(F
2) = 0.1248, T = 293(2) K.
The crystal structure of methyl N-(4-bromophenyl)carbamate, C8H8BrNO2
Authors: Karczmarzyk Zbigniew , Pitucha Monika , Wysocki Waldemar , Morawiak Maja , Sobótka-Polska Karolina , Urbańczyk-Lipkowska Zofia 
Published: September 2017

Abstract
C8H8BrNO2, orthorhombic, Pbca (no. 61), a = 10.1313(3) Å, b = 8.5416(4) Å, c = 20.4597(7) Å, V = 1770.53(12) Å3, Z = 8, R
gt(F) = 0.0394, wR
ref(F
2) = 0.1214, T = 296 K.
(E)-N-benzylidene-3-(benzylthio)-5-p-tolyl-4H-1,2,4-triazol-4-amine, C23H20N4S
Authors: Ding Qichun , Dai Shudong , Guo Hongxu , Zhang Li-Xue 
Published: September 2017

Abstract
C23H20N4S, Monoclinic, P21/n (no. 14), a = 11.439(3) Å, b = 8.868(2) Å, c = 20.557(5) Å, β = 104.542(4)°, V = 2018.7(8) Å3, Z = 4, R
gt(F) = 0.0449, wR
ref(F
2) = 0.1266, T = 298(2) K.
The crystal structure of N,N-dimethyl-2,6-di-p-tolylpyrimidin-4-amine, C20H21N3
Authors: Zhang Zhi-Mao , Chen Lian-Hui 
Published: September 2017

Abstract
C20H21N3, Orthorhombic, Pbca, a = 12.2422(16) Å, b = 7.1996(10) Å, c = 39.037(5) Å, V = 3440.6(8) Å3, Z = 8, R
gt(F) = 0.0686, wR
ref(F
2) = 0.1723, T = 293(2) K.
The “Idea” of Universal History: What the Owl Heard, the Angel Saw, and the Idiot Said
Authors: Bowden Brett 
Published: September 2017

AbstractThis essay considers the similarities and differences between world history, global history, and universal history. It demonstrates how a philosophical, and specifically a teleological, understanding of history is central to the idea of universal history. To a certain extent, this philosophical version of universal history transcends both world history and global history in that some versions of each of those are in fact universal histories of this very kind.