bluuebunny/crossref_metadata_2025_split huggingface dataset:
MK2/3 Are Pivotal for IL-33–Induced and Mast Cell–Dependent Leukocyte Recruitment and the Resulting Skin Inflammation
Authors: Drube Sebastian , Kraft Florian , Dudeck Jan , Müller Anna-Lena , Weber Franziska , Göpfert Christiane , Meininger Isabel , Beyer Mandy , Irmler Ingo , Häfner Norman , Schütz Dagmar , Stumm Ralf , Yakovleva Tatiana , Gaestel Matthias , Dudeck Anne , Kamradt Thomas 
Published: October 2016

Abstract
The IL-1R family member IL-33R mediates Fcε-receptor-I (FcεRI)-independent activation of mast cells leading to NF-κB activation and consequently the production of cytokines. IL-33 also induces the activation of MAPKs, such as p38. We aimed to define the relevance of the p38-targets, the MAPK-activated protein kinases 2 and 3 (MK2 and MK3) in IL-33-induced signaling and the resulting mast cell effector functions in vitro and in vivo. We demonstrate that the IL-33-induced IL-6 and IL-13 production strongly depends on the MK2/3-mediated activation of ERK1/2 and PI3K signaling. Furthermore, in the presence of the stem cell factors, IL-33 did induce an MK2/3-, ERK1/2- and PI3K-dependent production of TNF-α. In vivo, the loss of MK2/3 in mast cells decreased the IL-33-induced leukocyte recruitment and the resulting skin inflammation. Therefore, the MK2/3-dependent signaling in mast cells is essential to mediate IL-33-induced inflammatory responses. Thus, MK2/3 are potential therapeutic targets for suppression of IL-33-induced inflammation skin diseases such as psoriasis.
CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes
Authors: Dee Christopher T. , Nagaraju Raghavendar T. , Athanasiadis Emmanouil I. , Gray Caroline , Fernandez del Ama Laura , Johnston Simon A. , Secombes Christopher J. , Cvejic Ana , Hurlstone Adam F. L. 
Published: October 2016

Abstract
CD4+ T cells are at the nexus of the innate and adaptive arms of the immune system. However, little is known about the evolutionary history of CD4+ T cells, and it is unclear whether their differentiation into specialized subsets is conserved in early vertebrates. In this study, we have created transgenic zebrafish with vibrantly labeled CD4+ cells allowing us to scrutinize the development and specialization of teleost CD4+ leukocytes in vivo. We provide further evidence that CD4+ macrophages have an ancient origin and had already emerged in bony fish. We demonstrate the utility of this zebrafish resource for interrogating the complex behavior of immune cells at cellular resolution by the imaging of intimate contacts between teleost CD4+ T cells and mononuclear phagocytes. Most importantly, we reveal the conserved subspecialization of teleost CD4+ T cells in vivo. We demonstrate that the ancient and specialized tissues of the gills contain a resident population of il-4/13b–expressing Th2-like cells, which do not coexpress il-4/13a. Additionally, we identify a contrasting population of regulatory T cell–like cells resident in the zebrafish gut mucosa, in marked similarity to that found in the intestine of mammals. Finally, we show that, as in mammals, zebrafish CD4+ T cells will infiltrate melanoma tumors and obtain a phenotype consistent with a type 2 immune microenvironment. We anticipate that this unique resource will prove invaluable for future investigation of T cell function in biomedical research, the development of vaccination and health management in aquaculture, and for further research into the evolution of adaptive immunity.
MATLAB as a tool as Analysis and Problem Solving Competency Development in Chemical Engineering Degree using MATLAB
Authors: López-Pérez Maria-Fernanda , Cardona S. C. , Lora J. , Abad A. 
Published: October 2016

<p class="Textoindependiente21"><span lang="EN-US">Analysis and solving problems is a Chemical Engineering student capability. In order to develop this ability, activities that encompass problem-solving by students may involve problems in real-world settings. </span></p><p class="Textoindependiente21"><span lang="EN-US">In Chemical Engineering degree, MATLAB is a numerical software package that helps in the process of designing, evaluating and implementing a strategy to answer an open-ended question or achieve a desired goal. In this context, Matlab is software used in process simulation. Several lectures of Escuela Politécnica Superior d’Alcoi presented an innovation and improvement educational research project (PIME) in order to used MATLAB, like coordination teaching tool between some subjects.</span></p><p class="Textoindependiente21"><span lang="EN-US">The principal purpose of this work is the students improvement using, as has been mentioned previously, MATLAB in a problem-based learning methodology. This methodology allows a more effective coordination in the degree. The present paper presents a real- world problem and the common elements of most problem-solving contexts and how is designed to function across all disciplines.</span></p>
Engaging and Assessing Students through their Electronic Devices and Real Time Quizzes
Authors: Ferrándiz E. , Puentes C. , Moreno P. J. , Flores E. 
Published: October 2016

<p>This paper describes a teaching experience using Socrative, a third party electronic tool, for real-time questioning in lectures of Econometrics. Econometrics is a theoretical-practical subject, but traditionally a large proportion of our students tend to focus on the practical and discard the theory, often skipping classes on theory and avoiding studying its content, probably motivated by its complexity. As a consequence, students’ marks obtained in the theoretical part of the exam are usually low. In this context, we put forward a change in our teaching methodology to include the use of Socrative, a freely available app, that allows students to answer teachers’ short, true/false, or multiple choice questions posed during each class using their smartphones (or other electronic devices with Internet connection). The objectives of this project are twofold: 1) to engage students and increase attendance at lectures; 2) to improve feedback on the learning process. The results of a survey of a sample of 186 students reveal that Socrative has been an effective tool for achieving these objectives.</p>
Applied Mathematical Problems in Engineering
Authors: Llopis-Albert Carlos , Palacios-Marques Daniel 
Published: October 2016

There is a close relationship between engineering and mathematics, which has led to the development of new techniques in recent years. Likewise the developments in technology and computers have led to new ways of teaching mathematics for engineering students and the use of modern techniques and methods. This research aims to provide insight on how to deal with mathematical problems for engineering students. This is performed by means of a fuzzy set/Qualitative Comparative Analysis applied to conflict resolution of Public Participation Projects in support to the EU Water Framework Directive.
DISTRIBUIÇÃO DOS MOLUSCOS TRANSMISSORES DA ESQUISTOSSOMOSE NO MUNICÍPIO ENDÊMICO DE SÃO BENTO, MARANHÃO, BRASIL
Authors: Araújo Nogueira Ranielly , Sampaio Lira Maria Gabriela , Silva Miranda Guilherme , Mendes Rodrigues João Gustavo , Carvalho Gomes Gleycka Cristine , Silva-Souza Nêuton 
Published: October 2016

Neste estudo, objetivou-se mapear os criadouros de Biomphalaria spp., transmissoras da esquistossomose mansoni, presentes no município de São Bento, localizado na região da Baixada Maranhense, área na qual esta doença é endêmica. Foram visitados 16 dos 22 bairros existentes na cidade durante o período de agosto de 2012 a julho de 2013. Os caramujos foram coletados com auxílio de conchas de captura e pinças, armazenados e transportados para o Laboratório de Parasitologia Humana da Universidade Estadual do Maranhão, em São Luís, onde foram acondicionados em aquários de vidro e alimentados com folhas de alface. Os moluscos foram submetidos à análise parasitológica à procura de estágios larvais de Schistosoma mansoni e identificados pela conquiliologia e por meio de dissecções. Em 18 criadouros mapeados foram obtidos 1.195 exemplares de Biomphalaria glabrata e de B. straminea. Nenhummolusco eliminou cercárias de S. mansoni. Considerando os resultados obtidos e os aspectos epidemiológicos relacionados à transmissão da esquistossomose, o mapeamento das espécies vetoras no município permitirá a localização e identificação dos criadouros, o que poderá auxiliar substancialmente os serviços de saúde locais nas atividades de vigilância e controle da esquistossomose, além de nortear futuros estudos epidemiológicos sobre a esquistossomose mansoni na região da Baixada Maranhense.
Cyclic voltammetric study of tin hexacyanoferrate for aqueous battery applications
Authors: Gromadskyi Denys , Chervoniuk Volodymyr , Kirillov Sviatoslav 
Published: October 2016

<p><span lang="EN-US">A hybrid composite containing 65 mass % of tin hexacyanoferrate mixed with 35 mass % of carbon nanotubes has been synthesized and its electrochemical behavior as a negative electrode in alkali metal-ion batteries has been studied in 1 mol L<sup>-1</sup> aqueous solution of sodium sulfate. The specific capacity of pure tin hexacyanoferrate is 58 mAh g<sup>-1</sup>, whereas the specific capacity normalized per total electrode mass of the composite studied reaches 34 mAh g<sup>-1</sup>. The estimated maximal specific power of an aqueous alkali-metal ion battery with a tin hexacyanoferrate electrode is ca. 3.6 kW kg<sup>-1</sup> being comparable to characteristics of industrial electric double-layer capacitors. The maximal specific energy accumulated by this battery may reach 25.6 Wh kg<sup>-1</sup> at least three times exceeding the specific energy for supercapacitors.</span></p>
Preparation of NiO-graphene oxide nanosensor for adsorptive stripping voltammetric determination of dinoterbon in food samples
Authors: Roja Kasaram , Prasad Puthalapattu Reddy , Sandhya Punyasamudram , Sreedhar Neelam Yugandhar 
Published: October 2016

<p class="PaperAbstract"><span lang="EN-US">Graphene oxide (GO) modified NiO electrochemical nanosensor was developed for the determination of the dinoterbon in food samples using adsorptive stripping voltammetry. The modified nanosensor characterized by TEM, XRD, cyclic and adsorptive stripping voltammetry. Dinoterbon pesticide exhibited a single well-deﬁned cathodic peak at pH 4.0 at Britton–Robinson buffer (-810.0 mV). The voltammetric characterization of the pesti­cide residues is evaluated and the parameter such as the effect of pH, scan rate, pulse amplitude, deposition potential and deposition time were optimized. The current–concen­tration plot obtained using this peak was straight-lined over the range from 0.05 to 50.00 µg mL<sup>-1 </sup>with limit of detection (LOD) 0.028 µg mL<sup>-1</sup>. The proposed method was efficiently applied to the determination of dinoterbon in food samples. The mean recoveries of the pesticide 97.40 to 99.88 % with a relative standard deviation of 0.114 % in food samples respectively.</span></p><br /><p><strong> </strong></p>
O Livro Vermelho de Jung na visão de Walter Boechat - Resenha
Authors: Moura Lauro Eustáquio Guirlanda de 
Published: October 2016

<p>Resenha:</p><p>BOECHAT, Walter. <strong>O Livro Vermelho de C. G. Jung. </strong>Petrópolis: Vozes, 2014. </p>
A leitura das narrativas sagradas: uma crítica à exegese tradicional à luz da Semiótica da Cultura e Teorias Narrativas
Authors: Terra Kenner Roger Cazotto 
Published: October 2016

<p class="Padro">A interdisciplinaridade, tema caro para as pesquisas científicas, gerou profundas e renovadoras mudanças nas perguntas feitas aos textos, que giravam sempre em torno da autoria, fundo histórico e genealogia de tradições. Observando a história do estabelecimento das ciências da religião, desde os primeiros trabalhos de Max Müller, sabe-se que a leitura das narrativas sagradas foi fundamental. Estas são expressões de linguagem oral ou escrita do ambiente religioso. Neste texto, serão apresentadas as intuições da semiótica da cultura de I. Lótman e colocadas em diálogo com as teorias narrativas, para serem pensados pressupostos epistemológicos e metodologias, menos devedores das metodologias historicistas, a fim de servirem de instrumento para interpretação destes textos sacralizados pelas comunidades religiosas. Para este feito, serão apresentados e discutidos conceitos como <em>texto, cultura, memória e narrativa</em>, os quais permitirão fazer as devidas críticas às metodologias tradicionais que se cristalizaram na prática interpretativa, especialmente na exegese filha da Modernidade, como, também, propor novas perguntas e caminhos na compressão dos textos das religiões. </p>
Příčiny vojenského převratu: syntetizovaný kauzální model
Authors: Martinák Lukáš 
Published: October 2016

The article is an advancement of a preceding text which analyzed particular substantive theories of military coup in mainstream Anglo-Saxon political science literature. It provides a synthesis analysis of the previously analyzed literature specialized in military coup research, and because each substantive theory provides explanations of the occurrence of military coups through different independent variables, these factors are categorized for research purposes. Working with the definition of a military coup, the article’s goal is to set ten separate theories together into a formal concept of the military coup and express it by means of a synthesized causal model. This model contains individual premises of existing research and constitutes a conceptual framework for the formulation of “the hammer and anvil theory” of military coup. The “hammer” signifies the capacity and commitment of the army to effect a change of government by the use of force or under the threat of it. The “anvil” represents factors which delegitimize a government and de facto hamper its ability to escape the “hammer” blow.
Tarpfazinės sąveikos ir kondensacijos tyrimai
Authors: Šeporaitis Marijus , Valinčius Mindaugas , Gasiūnas Stasys , Laurinavičius Darius , Pabarčius Raimondas , Kaliatka Algirdas , Almenas Kazys 
Published: October 2016

Straipsnyje apžvelgiami 2005–2015 m. vykdyti skaitiniai ir natūriniai tyrimai besikondensuojančio dvifazio tekėjimo srityje. Pristatoma sukurta šiluminės-hidraulinės schemos koncepcija, kurioje šilumnešis cirkuliuoja varomas kondensacijos, eksperimentinis stendas, naudoti tyrimų metodai ir pasiekti rezultatai. Kombinuojant eksperimentų duomenis su skaitinio tyrimo rezultatais ištirta kondensacijos intensyvumo įtaka tarpfazinei trinčiai. Nagrinėjant turbulencijos struktūrą stačiakampiame eksperimentiniame kanale, optinės termografijos ir matematinės vaizdų analizės metodais aptiktas turbulencijos susižadinimo dvifazėje besikondensuojančioje tėkmėje reiškinys.
Critical Success Factors for Integrated Library System Implementation in Academic Libraries: A Qualitative Study
Authors: Yeh Shea-Tinn , Walter Zhiping 
Published: October 2016

Integrated library system (ILS) supports the entire business operations of an academic library from acquiring and processing library resources to making them available to user communities and preserving them for future use. As libraries’ needs evolve, there is a pressing demand for libraries to migrate from one generation of ILS to the next. This complex migration process is often the single largest investment in both budget and personnel involvement, but its success is by no means guaranteed. We draw upon enterprise resource planning (ERP) and critical success factors (CSFs) literature to identify the most salient CSFs for ILS migration success through a qualitative study with four cases. We identified that top management involvement, vendor support, user involvement, selection process, project team competence, project management and tracking, interdepartmental communication, data analysis and conversion, user education and training, and user emotion management are the CSFs that determine a migration project success.
Keywords: Integrated library systems, information systems, library automation, critical success factors, and academic libraries.
SIERRA GONZÁLEZ, Ángela (ed.) (2015): Discursos políticos, identidades y nuevos paradigmas de gobernanza en América Latina, Barcelona: Laertes..
Authors: Pérez Rosales Elisa 
Published: October 2016

<p> </p><p>Esta recopilación expone la necesidad de retomar el análisis de los cambios políticos y económicos producidos en América Latina en las últimas décadas. En ella se señala cómo estos cambios han influido en las relaciones continentales sobre todo en la configuración de la gobernanza interna de las naciones. Los relatos subrayan los avancen en democracia y en inclusión social, de tal manera que el discurso llegue a entenderse como una forma de organizar los modos de vida de las distintas sociedades y, también, de las instituciones. Este volumen, y sus XIII aportaciones, proponen una serie de discursos alternativos que situados frente al hegemónico vigente, devuelven un monográfico fundamental para el mejor entendimiento político, identitario y cultural del marco continental necesitado de nuevos paradigmas de gobernanza. </p><p><strong><br /></strong></p>
The role of anglers' perceptions and habits in biological invasions: perspectives from the Iberian Peninsula
Authors: Banha Filipe , Diniz António , Anastácio Pedro Manuel 
Published: October 2016

Abstract

Anglers are a recognized vector for invasive fauna, with both intentional and accidental introductions reported worldwide.
The purpose of this study was to investigate the Iberian freshwater angler's habits and perceptions related to biological invasions, using an international and bilingual survey in Spain and Portugal.
The results showed that anglers from both countries cover great distances to fish, and that they commonly visit several places and fish during consecutive days, representing a major risk for invasions. Yet, anglers' activity patterns throughout the year are not constant: the summer months involve more intense activity and, hence, entail higher risk.
In both countries, the preferred fish species were invasive, and their introductions were reported more often than native species, with motivations being country‐dependent.
The use of live bait was not frequent, but sometimes invasive species were used and the release of unused bait in the water was reported very frequently.
Most anglers recognize that introductions have environmental impacts and that anglers have an active role in intentional introductions. However, only a minority is aware of the angler's role in accidental transportation of invasive species.
These findings on anglers' behaviour patterns and perceptions may be used to model invasion risks and also improve monitoring and awareness programmes led by government agencies.
Copyright © 2016 John Wiley & Sons, Ltd.
Psychosocial Influences on Acceptability and Feasibility of Salivary Cortisol Collection From Community Samples of Children
Authors: Condon Eileen M. 
Published: October 2016

AbstractSalivary cortisol is considered to be a safe and noninvasive measure of hypothalamic‐pituitary‐adrenal axis functioning, and is a commonly measured biomarker of the human stress response in pediatric research. However, cortisol is highly variable and sensitive to a wide range of factors, creating a challenge for reliable salivary cortisol collection in the community setting. Furthermore, the acceptability of salivary cortisol collection in community samples of children is largely unknown. The purpose of this integrative review was to investigate current evidence on the acceptability and feasibility of salivary cortisol collection in community samples of children. In an analysis framed by the Theory of Planned Behavior, data extracted from 31 studies revealed six categories of psychosocial influences on acceptability and feasibility: uncertainty and misconceptions, cultural and ethnic values, family rules and values, difficulty following protocols and procedures, burden of multiple samples, and child refusal or resistance. Further research is required to fully understand the factors that influence acceptability and feasibility of salivary cortisol collection in community samples of children. Understanding individual, family, and community perceptions of biobehavioral research will lead to more culturally sensitive and feasible community‐based research methods. © 2016 Wiley Periodicals, Inc.
A Case Study of Engaging Hard‐to‐Reach Participants in the Research Process: Community Advisors on Research Design and Strategies (CARDS)®
Authors: Kaiser Betty L. , Thomas Gay R. , Bowers Barbara J. 
Published: October 2016

AbstractLack of diversity among study participants in clinical research limits progress in eliminating health disparities. The engagement of lay stakeholders, such as patient or community advisory boards (CABs), has the potential to increase recruitment and retention of underrepresented groups by providing a structure for gathering feedback on research plans and materials from this target population. However, many CABs intentionally recruit prominent stakeholders who are connected to or comfortable with research and academia and thus may not accurately represent the perspectives of underrepresented groups who have been labeled hard‐to‐reach, including racial minorities and low‐income or low‐literacy populations. We developed a partnership between the University of Wisconsin‐Madison School of Nursing and two community centers to deliberately engage hard‐to‐reach people in two lay advisory groups, the Community Advisors on Research Design and Strategies (CARDS)®. Community center staff recruited the CARDS from center programs, including parenting and childcare programs, women's support groups, food pantries, and senior meal programs. The CARDS model differs from other CABs in its participants, processes, and outcomes. Since 2010, the CARDS have met monthly with nurses and other researchers, helping them understand how research processes and the language, tone, appearance, and organization of research materials can discourage people from enrolling in clinical studies. We have successfully used the CARDS model to bring hard‐to‐reach populations into the research process and have sustained their participation. The model represents a promising strategy for increasing the diversity of participants in clinical research. © 2016 Wiley Periodicals, Inc.
Sit‐To‐Stand Lift: Effects of Lifted Height on Weight Borne and Upper Extremity Strength Requirements
Authors: Tang Ruoliang , Poklar Maggie , Domke Hilary , Moore Stephanie , Kapellusch Jay , Garg Arun 
Published: October 2016

AbstractTo prevent back and shoulder injuries to nursing personnel, sit‐to‐stand lifts are used to transfer partial‐weight‐bearing patients with upper extremity strength. However, the weight‐bearing capacity and upper extremity strength required of patients have not been defined. The objectives of this study were to determine: (a) the percentage of body weight borne by the patient when lifted to different heights in the lift and (b) whether a patient needs upper extremity strength. Nineteen healthy normal‐weight volunteers (ages 19–39) were transferred from a hospital bed to a wheelchair using (a) a gait belt and (b) a sit‐to‐stand lift. With legs secured in the lift, participants were lifted to five different heights (knee angles 120–180 degrees) while holding and not holding the lift handles. Participants supported a greater percentage of body weight as they were lifted higher, increasing from 60% to almost 100% (p < .01). Holding the handles did not have an effect on weight borne overall. At low heights, slightly less weight was borne when not using the handles than with them, and no difference in weight borne was found at heights near standing (p < .01). All participants felt more comfortable and safer transferring from bed to wheelchair with the mechanical lift than with the gait belt (p < .01). Results are limited to normal‐weight patients but suggest that sit‐stand lifts can be used in patients without upper extremity strength. Patients with limited weight‐bearing capacity can be transferred by not raising them high in the lift. © 2016 Wiley Periodicals, Inc.