bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intratumoral and peritumoral lymphatic vessel density both correlate with lymph node metastasis in breast cancer
Authors: Zhang Song , Yi Shanhong , Zhang Dong , Gong Mingfu , Cai Yuanqing , Zou Liguang 
Published: January 2017

AbstractThe status of lymph node involvement is an important prognostic factor for breast cancer. However, the presence of intratumoral lymphatic vessels in primary tumor lesions and the relationship between lymphatic vessel density (LVD) and lymph node metastasis (LNM) have not been firmly established. Therefore, we performed a meta-analysis study to investigate these issues. According to the pre-established inclusion and exclusion criteria, 13 studies, involving 1029 breast cancer patients, were included in this study. Using immunohistochemical staining, intratumoral lymphatic vessels were detected in 40.07% of breast cancer patients (240/599), and peritumoral lymphatics were detected in 77.09% (397/515). All studies demonstrated that peritumoral LVD was higher than intratumoral LVD, with a pooled standard mean difference and 95% confidence interval (95% CI) of 1.75 (1.28 to 2.21). Both intratumoral LVD and peritumoral LVD positively correlated with LNM, with correlation coefficients of 0.14 (95% CI 0.05 to 0.23) and 0.31 (95% CI 0.13 to 0.49), respectively. In summary, our study reports the overall detection rate of intratumoral lymphatics and demonstrates the associations between intratumoral LVD, peritumoral LVD, and LNM in breast cancer. Additionally, controlled studies with a larger number of subjects are needed to establish these relationships.
BCL11B gene heterozygosity causes weight loss accompanied by increased energy consumption, but not defective adipogenesis, in mice
Authors: Inoue Jun , Ihara Yusuke , Tsukamoto Daisuke , Yasumoto Keisuke , Hashidume Tsutomu , Kamimura Kenya , Hirano Shigeki , Shimizu Makoto , Kominami Ryo , Sato Ryuichiro 
Published: January 2017

Abstract
BCL11B is a zinc finger-type transcription factor that regulates the development of the white adipose tissue (WAT), skin, central nervous system, and immune system. BCL11B is required for proper adipocyte differentiation, and BCL11B−/− embryos at E19.5 have very low amounts of the subcutaneous WAT. Here, we demonstrated that BCL11B+/− mice have lower body weight than BCL11B+/+ mice, whereas the expression of adipogenic marker genes in the WAT was comparable between BCL11B+/+ and BCL11B+/− mice. Histological analysis indicated that BCL11B+/− mice fed a high-fat diet have much smaller white adipocytes and lipid droplets in the WAT and liver, respectively. In addition, BCL11B+/− mice had increased energy consumption under both standard and high-fat diets. Thus, this study identifies BCL11B as a regulator of energy metabolism, and it is unlikely that BCL11B functions in the WAT contribute to energy metabolism in BCL11B+/− mice.
Applying a new concept of corrosion protection in the presence of water: hydrojetting application – effectiveness lab test
Authors: Genovez Mario Celso , Araujo Luiz Henrique , Pinto Tiago Dinis , Hrdina Radim 
Published: January 2017

Purpose
This paper aims to describe the results of lab testing of a newly developed organic inhibitor V-active VCIs. The findings demonstrate that it is possible to eliminate or reduce the oxidizing action of water, thereby extending the allowable time before painting after hydrojetting, and that the new corrosion inhibitor technology does not interfere with the final quality of paint adhesion.

Design/methodology/approach
Metallic specimens were treated/washed in standard lab condition. A 2 per cent V-active VCI SPH1712 water solution was prepared by diluting the inhibitor in industrial water. Metal sample plates were examined after blasting and after subsequent drying, and were submitted to the paint adhesion tests, cathodic disbondment, total soluble salts, time for formation of flash rust and cyclic corrosion test type III (20 cycles), to evaluate the duration of temporary protection and oxidation prevention and influence on paint adherence.

Findings
Using the V-active VCI proposed technology, it was possible to minimize or eliminate the oxidizing action of the water when the metal is exposed to saline moisture in a closed environment, extending the acceptable time before painting without interfering with the final quality of painting.

Practical implications
The proposed technology allows an increase in the prepared (wet blasted) steel surface during cleaning and preparation, thereby reducing labor and product costs, and reduces water consumption during the preparation process. Practical applications in the shipbuilding, ship maintenance and oil and gas production industries include the preservation of internal tubes and pipes, protection during hydrostatic test processes and cleaning with water and corrosion prevention in diesel tanks contaminated with water.

Originality/value
The intent of this paper is to present the obtained results for a new formulation of organic chemical inhibitors that use water as the application medium. In addition to this property, this group of organic inhibitors maintains the properties of volatile inhibitors. Thus, these compounds are generically known as V-active VCIs.
Preparation and corrosion behavior of cerium (III)-modified and electro-assisted deposited bis-1,2-[triethoxysilyl] ethane film on the aluminum alloy AA2024-T3
Authors: Peng Dongdong , Wu Junsheng , Chu Pingping , Li Xiaogang 
Published: January 2017

Purpose
This paper aims to investigate the effect of cerium modification and electrodeposition on the properties of the silane films obtained. Besides, the influence of dissolved oxygen was also researched through inhalation of oxygen or nitrogen. Moreover, the corresponding corrosion behavior of the silane films was also studied.

Design/methodology/approach
In this paper, surface morphology and corrosion-resistant properties of the films were characterized by scanning electron microscopy, electrochemical impedance spectroscopy, immersion test and the salt spray test.

Findings
The paper reveals that all the practical parameters including the concentration of dissolved oxygen had a marked effect on the anti-corrosive performance of the films, which may be attributed to the dense and compact structure of the films obtained. Furthermore, the self-healing ability of the films had also been enhanced through the rise of dissolved oxygen concentration in proper proportion.

Originality/value
This paper reveals the effect of practical parameters on the properties of the silane films obtained and the corrosion behavior of these films.
What stories unfold: empirically grasping value co-creation
Authors: Hansen Anne Vorre 
Published: January 2017

PurposeThe aim of this paper is to give an empirical illustration of value co-creation and to argue for narrative methodology as a fruitful analytical strategy when exploring the processes of value co-creation.Design/methodology/approachThrough an in-depth case study in the non-profit housing sector in Denmark, the research explored how residents perceive and co-create value in a long-term service relationship. The point of departure is an understanding of value co-creation as a phenomenological construct determined by the beneficiary, and the research is based primarily on the perspectives of service-dominant logic and customer-dominant logic.FindingsThe research elucidated how value is both socially created and deconstructed through stories. Moreover, narrative analysis revealed how residents’ perceptions of services are deeply embedded in context and time. In this way, the study highlighted that the co-creation of value is inherently social and temporal.Practical implicationsUnderstanding how value is perceived and negotiated by customers might assist practitioners to refine their understanding of value co-creation and lead them to address customers in more nuanced ways.Originality/valuePrevailing streams in service research on value co-creation argue for more studies and empirically grounded examples of value co-creation processes, especially those based in the customer sphere. This paper contributes to such an enhanced understanding of the process of value co-creation and gives the outline of a new methodology for studies in this specific area of service research.
Innovation in infrastructure projects: an Australian perspective
Authors: Maghsoudi Soroush , Duffield Colin , Wilson David 
Published: January 2017

Purpose
Unlike manufacturing and research and developments, major infrastructure projects rarely emphasize or drive their objectives on the basis of innovation. This is in part because of a risk-averse culture, yet conceivably great benefits and opportunities are being lost because of this behavior.

Design/methodology/approach
The case for focusing on innovation in infrastructure projects is that the reasons driving innovation are not fully understood, and this impedes the effective implementation of lessons learned for the numerous innovative projects into practice more generally. The purpose of this study was to discover how innovation is produced and captured in major infrastructure projects in Australia and to understand how innovation may be replicated for future projects through refinement of design, project management, finance and procurement.

Findings
Engineering and project managers may find this paper helpful to better understand how innovation might happen in infrastructure projects and what different forms it can take.

Originality/value
The findings of this study demonstrate that people and culture drive consistent successful infrastructure outcomes more than simply the development of new products or processes.
Applying project management for new service development
Authors: Su Chun-Hsien , Chen Ping-Kuo 
Published: January 2017

Purpose
This paper aims to provide an innovative solution on new service development (NSD) implementation by the project management competences and processes of IPMA ICB 3.0 and PMI PMBOK Guide 5th E.

Design/methodology/approach
By breaking NSD work breakdown structure into five control accounts, each account has its own suggested work packages concluded from reviewed literatures.

Findings
This research sequentially presents proper PM competences and processes as solutions for these control accounts and their work packages.

Research limitations/implications
This study was to provide an innovative solution on NSD implementation by the project management competences and processes of IPMA ICB 3.0 and PMI PMBOK Guide 5th E. By breaking NSD work breakdown structure into five control accounts, each account has its own suggested work packages concluded from reviewed literatures. This research sequentially presents proper PM competences and processes as solutions for these control accounts and their work packages. Consequently, we concluded that the PM competences and processes furnish a favorable base where any NSD project is suitable to deploy without compromising its original features.

Practical implications
Consequently, it is concluded that the PM competences and processes furnish a favorable base where any NSD project is suitable to deploy without compromising its original features.
Knowledge management in international cooperation for anti-money laundering
Authors: Yasaka Noriaki 
Published: January 2017

Purpose
The purpose of this paper is to construct a theoretical hypothesis to explain the organizational knowledge creation in international cooperation, which aims to contribute to practical problem solving in the process of knowledge creation.

Design/methodology/approach
This research reveals that anti-money laundering based on the concept of knowledge and organizational knowledge creation mechanisms could co-evolve in inter-organizational knowledge.

Findings
By simplifying the knowledge flow of anti-money laundering in international cooperation, the author illustrates the process of knowledge creation, sharing and utilizing.

Originality/value
This paper used the example of international anti-money laundering activities to describe knowledge creation, process of knowledge management, organizational structure and the emergence of international cooperation.
On the plastic moment-shear interaction curves of steel sections under fire
Authors: Dwaikat Mahmud M.S. 
Published: January 2017

Purpose
Different approaches, originally developed for ambient conditions, exist in current codes and standards for incorporating the effect of moment–shear (M–V) interaction on the plastic-carrying capacity of wide-flanged (WF) steel sections. There is a lack of experimental and theoretical studies that address this issue under fire conditions.

Design/methodology/approach
The current paper presents a numerical study investigating the effect of fire exposure on the plastic M–V capacity curves of doubly symmetrical, WF, hot-rolled steel sections. Validated high-fidelity finite element (FE) models constructed via ANSYS are used to study the effect M–V interaction on the plastic capacity of WF sections. Also, a simplified plastic sectional analysis, intended to be used by engineering practitioners, is proposed for generating the plastic M–V interaction curves.

Findings
The study shows that the fire-induced non-uniform heating of the section plates affects the shape of the plastic M–V interaction capacity curves. Comparison of different methods against FE results shows that the method specified in the Eurocode is very conservative at room-temperature, but it turns out to be barely sufficiently conservative under fire conditions.

Originality/value
It is well noted that lack of fire tests on the M–V interaction, including the stability of the plates of steel sections under fire, make it difficult to reach a definite assessment on the effect of M–V interaction on the bearing capacity of steel beams.
Numerical simulation of the heating behaviour of steel profiles with intumescent coating adjacent to trapezoidal steel sheets in fire
Authors: Schaumann Peter , Tabeling Florian , Weisheim Waldemar 
Published: January 2017

Purpose
This paper aims to present numerical investigations regarding the heating behaviour of steel elements protected by an intumescent coating with an adjacent trapezoidal steel sheet.

Design/methodology/approach
For this purpose, a three-dimensional numerical model of a coated I-section profile is developed in Abaqus taking into account the restrained foaming process of the intumescent coating due to the adjacent member explicitly.

Findings
After the validation of the numerical model against own fire tests, the steel temperatures of a coated I-section profile with and without an adjacent trapezoidal steel sheet, resulting from fire exposure according to ISO-834, are compared to demonstrate the influence of the steel sheet in detail.

Originality/value
The main objective is to evaluate the influence of an unprotected trapezoidal steel sheet on the temperatures of coated I-section profiles.
An overview on tube inserts configurations and performances in tubular exchangers
Authors: Abu-Khader Mazen M. 
Published: January 2017

Purpose
The purpose of this paper is to update a previous review work (Abu-khader, 2006, Heat & Mass Transfer, Vol. 43 No. 2, pp. 123-134) and highlight the new research methods on the use of twisted tapes and the application of different configurations of these tape inserts. Also, based on a vast collection of experimental data in open literature, generalized Nusselt number (Nu) and friction factor (f) correlations as the function of twist ratio were developed with maximum error around ± 15 per cent. The present paper examines several case studies which apply complex configurations of twisted inserts.

Design/methodology/approach
Using the developed correlations, an equivalent Nusselt number and friction factor of typical type twist insert were generated which achieved the same performance of each complex configuration.

Findings
The open literature contains large number of wired and complex configurations of twisted tape inserts. Their applicability to real industrial use is questionable.

Originality/value
This paper presents an up-to-date review on the use of twisted tape in research, highlights the different tape configurations and proposes general correlations for traditional twisted tape inserts.
The percolation mechanism of surfactant-free microemulsions witnessed by the conductivity measurement
Authors: Li Zhen , Liu Xianwei , Lian Yiwei , Xie Juan , Gao Xiaorui , Chang Tao 
Published: January 2017

Purpose
This paper aims to report the conductivity measurement of ten different surfactant-free microemulsions (SFMEs)

Design/methodology/approach
The variations of electrical conductivity as a function of water volume fraction are examined at one constant alcohol (or DMF, ethyl lactate, γ-valerolactone)/water, alcohol (or DMF, ethyl lactate, γ-valerolactone)/oil volume ratios for each sample.

Findings
Most of the results are consistent with percolation character. The conductive mechanism of these SFMEs is discussed by the percolation model, and it is found that it might be described with the static percolation model below the percolation threshold.

Originality/value
Our report gives a systematic research on the percolation mechanism of as many species of SFMEs as possible by the theoretical models
The improvement of XD-MSM friction tester based on Labview
Authors: Wang Guimei , Li Xiaomei 
Published: January 2017

Purpose
With the widespread use and development of automobile, much attention has been paid to its security issues. So to ensure the driving safety, the automobile must be equipped with good braking performance. In the process of braking, the friction from friction pair causes continuous wear and tear of the surface of brake lining and increases the gap between break pairs, until the lining is not being used (Belhocinea et al., 2014); thus, it is very important to detect the lining wear rate.

Design/methodology/approach
This paper designed the automobile brake friction test wear rate detection system based on Labview.

Findings
Through the detect data, we find that the automobile brake lining wear rate detection system has higher detect accuracy, in the process of detection, the brake lining without the defects such as cracks and bulges, which shall effect the normal use, the lining has no remarkable scratch to disk friction surface, can completed meet the requirements of users.

Originality/value
The automobile brake friction test wear rate detecting system adopts the components of USB-9211 DAQ, optoNCDT1700 non-contract high accuracy displacement sensor, in addition the Labview software to complete the functions such as lining wear rate real time detection, data multichannel real time acquisition, display, and storage record, etc., and uses LabSQL to import the detecting data to Microsoft Access database, which can satisfy the demands of various customers. Moreover, the wear rate real time detection can reflect the lining’s wear regulation of different manufacturers and different material and provide a reliable basis for selecting the appropriate lining material and predicting the lining’s lifetime.
Investigation on the accurate parameter estimation of photovoltaic (PV) module based on simplified two-diode model
Authors: Chitti Babu B. , Gurjar Suresh , Cermak Tomas 
Published: January 2017

Purpose
This paper aims to present a detailed investigation on the parameter estimation of a photovoltaic (PV) module by using a simplified two-diode model.

Design/methodology/approach
The studied PV module in this paper resembles an ideal two-diode model, and to reduce the computational time, the proposed model has a photocurrent source and two ideal-diodes and neglects the series and shunt resistances. Hence, for calculating the unknown parameters, only four parameters are required from the datasheet. Moreover, the studied model is simple and uses an easy modeling approach which is free from complexities.

Findings
The performance of the PV module is analyzed under non-standard test conditions by considering partial shading at different shaded levels, and it is found that the model has less computational time and gives accurate results.

Originality/value
The usefulness of this PV model is demonstrated with the help of several illustrative figures, and the performance of the PV module is evaluated.
Hourly global solar radiation estimation from MSG-SEVIRI images-case study: Algeria
Authors: Bouchouicha Kada , Razagui Abdelhak , Bachari Nour El Islam , Aoun Nouar 
Published: January 2017

Purpose
This paper aims to propose an approach based on physical model integration for surface and cloud albedo computation using an approximate form of the atmospheric radiative transfer equation and sun-pixel-satellite.

Design/methodology/approach
The data used in this study are global irradiance collected from for various sites in Algeria, and data were obtained from the processing of the high-resolution visible images taken by the Meteosat Second Generation satellite in 2010.

Findings
The results suggest that the standard deviation obtained with this method is similar to that obtained with current estimation methods. The hourly and daily correlation coefficients range between 0.95 and 0.97 and between 0.97 and 0.99, respectively. The hourly and daily mean bias errors range between −0.2 and +1.2 per cent and between −0.2 and +1.4 per cent, respectively. The hourly and daily root mean square errors range between 10 and 17 per cent and between 4 and 8 per cent, respectively.

Originality/value
This paper developed a new estimating method that derives the hourly global horizontal solar irradiation at a ground level from geostationary satellite data under local climate conditions.
The evaluation of anaerobic co-digestion and ethanol fermentation for bioenergy production from 200 ha farmland in the UK
Authors: Guk Erdogan , Kalkan Naci 
Published: January 2017

Purpose
Bioenergy as a renewable energy type is found as a promising method to replace non-renewable energy. Anaerobic co-digestion, in which the microorganisms of two or more substrates break into biodegradable materials without oxygen, and fermentation, in which substances break into a simpler form in the presence of microorganisms and some bacteria, are the two frequently used methods that are were applied in this work.

Design/methodology/approach
A farmland currently being used for farming was selected, and the bioenergy potential of the farmland was evaluated by using the aforementioned two methods. In this work, segregated municipal wastes which were collected from nearby areas and animal manure were used as feedstock for anaerobic co-digestion, whereas wheat straw obtained from the farmland was used as feedstock for fermentation.

Findings
The total input energy required for the digestion systems and the collection of the feedstock products from the growth to the harvest phases was calculated. Thereafter, the generated output energy was calculated to obtain an energy balance of the techniques. All the processes were taken into account during the prediction of the cost of the given power plant. The power output capacity of the farmland was 245 MW with a total cost of $540,200.

Research limitations/implications
Because of the chosen research approach, the research results may lack generalisability. Therefore, researchers are encouraged to test the proposed propositions further.

Originality/value
The result proves that the two methods were applicable and feasible to replace for the 200 ha farmland.