bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construindo a gestão estratégica sustentável: um estudo sobre a empresa Mercur S.A.
Authors: Alievi Rejane Maria , Antinarelli Alexandre 
Published: May 2016

The pressures for economic growth of organizations have been leading to society and companies to become aware that humanity lives in a world where natural resources are finite and that the impacts of this growth can cause damage for present and future generations. Thus, the present study aimed contributed with this discussion, under the perspective of sustainable development approach, evaluating how the organizational environment seeks to promote the confluence between enterprise strategies and sustainable strategic management. For this, it sought through a case study, qualitative and exploratory; retrieve the main theoretical approaches related to enterprise strategies and sustainable development. The results of the study allowed identifying that the development of organizational awareness of sustainability, contributed to the formulation process of sustainable business strategies.
Etapas necessárias para a implantação de um sistema de gestão integrado
Authors: Fernandes Jonathan Lucas Schwambach , Busanello Fernando , Polacinski Edio , Godoy Leoni Pentiado , Losekann Andresa Girardi , Lorenzett Daniel Benitti 
Published: May 2016

In the work environment in which we live today the deployment of management focused on quality have become an essential and indispensable to the proper performance of organizations that seek to address the current competitive market. This sense, there are organizations that seek adapt to this reality when try to make sure one of the quality standards accepted by the market, namely ISO 9001, 14001, SA 8000, and OHSAS 18001. Thus, based on the above it is emphasized that this article featured as a theoretical essay aims to present a comparative study of various cases, showing the steps required to deploy an Integrated Management System (IMS) consists of the four standards mentioned above. As a result of research presents a compilation of fourteen cases, as well as the deployment of an SGI used by each company.
Incorporating Archaeological Resources in Landscape-Level Planning and Management
Authors: Doelle William H. , Barker Pat , Cushman David , Heilen Michael , Herhahn Cynthia , Rieth Christina 
Published: May 2016

AbstractThe increasing importance of landscape-scale research and preservation goals within the archaeological profession coincides with expanded threats to the archaeological record through massive energy exploration and infrastructure projects and through the cumulative effects of smaller-scale development. It is further stimulated by the recognition that conservation strategies that span multiple resource classes and disciplines are best formulated at multiple and larger spatial scales. These are key drivers behind efforts to improve the ways that archaeological resources are considered in the context of development-related planning and implementation, including mitigation measures. In a prominent example, recent department-level direction from the Secretary of the Interior calls specifically for landscape-level planning as a critical component of responses to both large-scale development and climate change. This article reviews three current approaches to landscape-level planning in archaeology and calls for increased commitment to advancing their development and effectiveness.
Values-Based Management of Archaeological Resources at a Landscape Scale
Authors: McManamon Francis P. , Doershuk John , Lipe William D. , McCulloch Tom , Polglase Christopher , Schlanger Sarah , Sebastian Lynne , Sullivan Lynne 
Published: May 2016

AbstractPublic agencies at all levels of government and other organizations that manage archaeological resources often face the problem of many undertakings that collectively impact large numbers of individually significant archaeological resources. Such situations arise when an agency is managing a large area, such as a national forest, land management district, park unit, wildlife refuge, or military installation. These situations also may arise in regard to large-scale development projects, such as energy developments, highways, reservoirs, transmission lines, and other major infrastructure projects that cover substantial areas. Over time, the accumulation of impacts from small-scale projects to individual archaeological resources may degrade landscape or regional-scale cultural phenomena. Typically, these impacts are mitigated at the site level without regard to how the impacts to individual resources affect the broader population of resources. Actions to mitigate impacts rarely are designed to do more than avoid resources or ensure some level of data recovery at single sites. Such mitigation activities are incapable of addressing research question at a landscape or regional scale.
Validation of a Novel 3‐Dimensional Sonographic Method for Assessing Gastric Accommodation in Healthy Adults
Authors: Buisman Wijnand J. , van Herwaarden-Lindeboom Maud Y. A. , Mauritz Femke A. , El Ouamari Mourad , Hausken Trygve , Olafsdottir Edda J. , van der Zee David C. , Gilja Odd Helge 
Published: May 2016

Objectives: A novel automated 3‐dimensional (3D) sonographic method has been developed for measuring gastric volumes. This study aimed to validate and assess the reliability of this novel 3D sonographic method compared to the reference standard in 3D gastric sonography: freehand magneto‐based 3D sonography.Methods: A prospective study with 8 balloons (in vitro) and 16 stomachs of healthy volunteers (in vivo) was performed. After a 500‐mL liquid meal, 1 preprandial and 3 postprandial volume scans of the stomachs were performed by the novel 3D sonographic method and the current reference‐standard 3D sonographic method.ResultsThe in vitro study showed a mean volume difference between the novel method and the true balloon volume of −1.3 mL; limits of agreement (LoA) were small (−39.3 to12.3 mL), with an intraclass correlation coefficient (ICC) of 0.998. The in vivo study showed a mean gastric volume of 321 mL between the novel method and the freehand magneto‐based method, with a mean volume difference of −4.4 mL; LoA were −40.1 to 31.2 mL, and the ICC was 0.991. The intraobserver and interobserver variability rates were low, at 0.8 mL (LoA, −24.0 to 25.6 mL), with an ICC of 0.995, and 0.5 mL (LoA, of −26.8 to 27.8 mL), with an ICC of 0.999, respectively.ConclusionsThe novel 3D sonographic method with automated acquisition showed good agreement with the current reference‐standard gastric 3D sonographic method, with low intraobserver and interobserver variability. This novel 3D sonographic method is a valid and reliable technique for determining gastric accommodation.
Automated Analysis of Stereotypical Movements in Videos of Children With Autism Spectrum Disorder
Authors: Barami Tal , Manelis-Baram Liora , Kaiser Hadas , Ilan Michal , Slobodkin Aviv , Hadashi Ofri , Hadad Dor , Waissengreen Danel , Nitzan Tanya , Menashe Idan , Michaelovsky Analya , Begin Michal , Zachor Ditza A. , Sadaka Yair , Koler Judah , Zagdon Dikla , Meiri Gal , Azencot Omri , Sharf Andrei , Dinstein Ilan 
Published: September 2024

ImportanceStereotypical motor movements (SMMs) are a form of restricted and repetitive behavior, which is a core symptom of autism spectrum disorder (ASD). Current quantification of SMM severity is extremely limited, with studies relying on coarse and subjective caregiver reports or laborious manual annotation of short video recordings.ObjectiveTo assess the utility of a new open-source AI algorithm that can analyze extensive video recordings of children and automatically identify segments with heterogeneous SMMs, thereby enabling their direct and objective quantification.Design, Setting, and ParticipantsThis retrospective cohort study included 241 children (aged 1.4 to 8.0 years) with ASD. Video recordings of 319 behavioral assessments carried out at the Azrieli National Centre for Autism and Neurodevelopment Research in Israel between 2017 and 2021 were extracted. Behavioral assessments included cognitive, language, and autism diagnostic observation schedule, 2nd edition (ADOS-2) assessments. Data were analyzed from October 2020 to May 2024.ExposuresEach assessment was recorded with 2 to 4 cameras, yielding 580 hours of video footage. Within these extensive video recordings, manual annotators identified 7352 video segments containing heterogeneous SMMs performed by different children (21.14 hours of video).Main outcomes and measuresA pose estimation algorithm was used to extract skeletal representations of all individuals in each video frame and was trained an object detection algorithm to identify the child in each video. The skeletal representation of the child was then used to train an SMM recognition algorithm using a 3 dimensional convolutional neural network. Data from 220 children were used for training and data from the remaining 21 children were used for testing.ResultsAmong 319 behavioral assessment recordings from 241 children (172 [78%] male; mean [SD] age, 3.97 [1.30] years), the algorithm accurately detected 92.53% (95% CI, 81.09%-95.10%) of manually annotated SMMs in our test data with 66.82% (95% CI, 55.28%-72.05%) precision. Overall number and duration of algorithm-identified SMMs per child were highly correlated with manually annotated number and duration of SMMs (r = 0.8; 95% CI, 0.67-0.93; P &amp;lt; .001; and r = 0.88; 95% CI, 0.74-0.96; P &amp;lt; .001, respectively).Conclusions and relevanceThis study suggests the ability of an algorithm to identify a highly diverse range of SMMs and quantify them with high accuracy, enabling objective and direct estimation of SMM severity in individual children with ASD.
Heterogeneity of Residual Disease After Neoadjuvant Systemic Therapy in Breast Cancer
Authors: Tarantino Paolo , Hortobagyi Gabriel , Tolaney Sara M. , Mittendorf Elizabeth A. 
Published: September 2024

ImportanceOver the past 2 decades, systemic therapy for early-stage breast cancer has gradually moved from the adjuvant to the neoadjuvant setting. Administration of systemic therapy before surgery leads to potential improvements in surgical outcomes and allows for the assessment of the pathologic response to treatment. For patients with residual disease (RD), 3 adjuvant strategies have been shown to improve outcomes: (1) adjuvant trastuzumab emtansine for ERBB2-positive disease, (2) adjuvant capecitabine for triple-negative disease, and (3) adjuvant olaparib for patients with germline BRCA variants. Furthermore, studies are testing novel drugs in the postneoadjuvant setting. Given the potential to tailor adjuvant therapy based on the response to preoperative systemic therapy, recognizing the complexities of response to neoadjuvant therapy and moving beyond the binary paradigm of RD vs experiencing a pathologic complete response is becoming increasingly necessary.ObservationsNovel antibody-drug conjugates, anti-ERBB2 tyrosine kinase inhibitors, and immune checkpoint inhibitors are being evaluated as additional rescue options in phase 3 trials for patients with RD after neoadjuvant treatment. Concomitantly, the prognostic role of RD has been refined by the introduction of the residual cancer burden. In addition, the genomic landscape of RD has been found to be associated with long-term prognosis, as has the immune background of the disease evaluated via the presence of tumor-infiltrating lymphocytes. Lastly, the dynamics of circulating tumor DNA may allow for further improvement in prognostication by understanding which patients harbor detectable minimal RD.Conclusions and RelevanceEscalating adjuvant treatment has led to meaningful survival improvements among patients with breast cancer and RD after neoadjuvant therapy. Uncovering the anatomic and biological intricacies of RD will allow for increased precision in postneoadjuvant treatments, moving beyond the binary paradigm of RD vs pathologic complete response, toward more tailored rescue strategies in the adjuvant setting.
Magnesium Optrodes for Real‐Time Optical Monitoring of Water Transport in Ultrathin Encapsulations for Bioelectronics
Authors: Mariello Massimo , Kavungal Deepthy , Gallagher Aidan , Cleusix Marion Bianca , Rouèche Mélanie N. , Altug Hatice , Leterrier Yves , Lacour Stéphanie P. 
Published: September 2024

AbstractRecent studies investigated the hydrolysis of Magnesium (Mg) thin films, highlighting their potential use in biodegradable devices. Quantitatively monitoring the degradation rate and morphological changes of Mg through optical methods and light‐delivery devices offers an innovative, contactless technique, independent of electrical wiring. This method is particularly useful for challenging sensing applications. This study introduces a set of strategies based on Mg optrodes where hydrolysis drives the real‐time monitoring of biofluid penetration through thin‐film encapsulations for bioelectronics. This enables a straightforward assessment of their long‐term reliability, through a quantitative correlation between the water transmission rate (WTR) of the encapsulation and the Mg optical modifications. The optical response of the corroding Mg films deposited on glass substrates and multimode optical fibers tips, within the visible spectrum is characterized. Finally, it is demonstrated that nanopatterning of Mg films as plasmonic nanoantennas significantly enhances the sensitivity of the quantitative approach in the mid‐Infrared spectrum through localized plasmon effects. This method achieves a WTR detection of 6.9 × 10−3 gm−2 day−1 in phosphate buffer solution (25 °C), with a theoretical lower detection limit of ≈10−5 gm−2 day−1. These findings pave the way for the development of a new class of nano‐optical water‐permeation sensors.
Electrochemically Promoted Skeleton Transformation of 2,1‐Benzisoxazoles to Alkyl Sulfones
Authors: Wu Yun‐Qi , Ren Sai‐Yan , Zhu Yu , Cui Fei‐Hu , Pan Ying‐Ming , Tang Hai‐Tao 
Published: September 2024

AbstractThis study developed an electrochemically promoted skeleton transformation reaction of 2,1‐benzisoxazoles to synthesize alkyl sulfones. Alkyl sulfones were synthesized in 68–93% yield by using 2,1‐benzisoxazole and sulfonate as substrates, and acetonitrile and water as solvents. Mechanism studies showed that this reaction involves ring opening, removal of the oxygen atom of the 2,1‐benzisoxazoles, and C(sp3)‐sulfonylation under electrochemical conditions.
A Passive Perspiration Inspired Wearable Platform for Continuous Glucose Monitoring
Authors: Saha Tamoghna , Khan Muhammad Inam , Sandhu Samar Singh , Yin Lu , Earney Sara , Zhang Chenyang , Djassemi Omeed , Wang Zongnan , Han Jintong , Abdal Abdulhameed , Srivatsa Samarth , Ding Shichao , Wang Joseph 
Published: September 2024

AbstractThe demand for glucose monitoring devices has witnessed continuous growth from the rising diabetic population. The traditional approach of blood glucose (BG) sensor strip testing generates only intermittent glucose readings. Interstitial fluid‐based devices measure glucose dynamically, but their sensing approaches remain either minimally invasive or prone to skin irritation. Here, a sweat glucose monitoring system is presented, which completely operates under rest with no sweat stimulation and can generate real‐time BG dynamics. Osmotically driven hydrogels, capillary action with paper microfluidics, and self‐powered enzymatic biochemical sensor are used for simultaneous sweat extraction, transport, and glucose monitoring, respectively. The osmotic forces facilitate greater flux inflow and minimize sweat rate fluctuations compared to natural perspiration‐based sampling. The epidermal platform is tested on fingertip and forearm under varying physiological conditions. Personalized calibration models are developed and validated to obtain real‐time BG information from sweat. The estimated BG concentration showed a good correlation with measured BG concentration, with all values lying in the A+B region of consensus error grid (MARD = 10.56% (fingertip) and 13.17% (forearm)). Overall, the successful execution of such osmotically driven continuous BG monitoring system from passive sweat can be a useful addition to the next‐generation continuous sweat glucose monitors.
Training‐Augmented Ionic Switch for Logic Signal Modulation
Authors: Jia Rui , Duan Xiaozheng , Wang Kaige , Sun Fengqiang , Li Teng , Chen Zhu , Wang Le , Wang Gang , Feng Liang‐Wen , Sun Hengda , Zhu Meifang 
Published: September 2024

AbstractEfficient ionic conductivity switching is crucial for the progression of iontronics, where adaptability and dynamic control are desirable to the innovation of intelligent devices. One of the main challenges in the field is to develop materials that not only transit between distinct conductive states but also exhibit evolvable properties to enhance their functional capabilities. Addressing this, a reversible phase‐transition hydrated salt crystal ionic gel (RPSIG) for innovative ionic switch design is introduced. The RPSIG demonstrates an exceptional ability to modulate its ionic conductivity, with a switching ratio able to reach 5000‐fold after training. The training effect can be attributed to the enhanced synergistic interplay between crystallites and the polymer matrix, which leads to thermodynamic stabilization of the interfacial structure and induces a higher energy cost for ion migrations. Meanwhile, the RPSIG exhibits the capability to adjust its resistive‐capacitive properties in response to phase transitions, making it a versatile component for signal processing. Further application of RPSIG in intelligent latches and multifunctional hybrid circuits enables effective logic signal transmission, highlighting its potential in pioneering the development of advanced iontronic devices.
Purple nutsedge management in tomato plasticulture: A study on the effectiveness of preemergence herbicide S‐metolachlor and its co‐application with fertilizer enhancer and chelated iron
Authors: Tiwari Ruby , Sapkota Anish , Boyd Nathan , Kanissery Ramdas 
Published: September 2024

AbstractPurple nutsedge (Cyperus rotundus L.) poses a significant challenge to Florida tomato (Solanum lycopersicum L.) producers due to its ability to puncture plastic mulch, resilient tubers, and rapid rhizome proliferation. Preemergence herbicides effectively suppress purple nutsedge in tomatoes under plastic mulch. Although the impact of co‐application of herbicides with fertilizers has been studied in row crops, its potential in vegetable plasticulture systems remains unexplored. This study aimed to evaluate the effectiveness and crop safety of the preemergence herbicide S‐metolachlor, both as a standalone treatment and in combination with a fertilizer enhancer or chelated iron in tomato plasticulture. Field trials at the University of Florida's Southwest Florida Research and Education Center, Immokalee, FL, involved applying S‐metolachlor at the recommended rate of 1 kg a.i. ha−1 on raised beds before installing plastic mulch. The herbicide was applied as a blanket spray alone, mixed with fertilizer enhancer, and coated on chelated iron fertilizer. Results indicate that using S‐metolachlor alone effectively reduced purple nutsedge density compared to the nontreated control in both trials I and II. Combining S‐metolachlor with fertilizer enhancer or chelated iron resulted in a >30% and 57% reduction in purple nutsedge density, respectively, compared to the nontreated control in trial II. These treatments did not adversely impact chlorophyll content or crop yield (p > 0.05) compared to the nontreated control. Notably, tomato yield significantly (p < 0.05) decreased with increased purple nutsedge density at 4, 8, and 12 weeks after transplanting. Overall, the results from both trials suggest that using S‐metolachlor is an effective approach to reduce purple nutsedge infestation in plastic‐mulched raised beds without negatively impacting tomato health and productivity.
Enantioconvergent Cross‐Nucleophile Coupling: Copper‐Catalyzed Deborylative Cyanation
Authors: Vu Jonathan , Haug Graham C. , Li Yongxian , Zhao Biyu , Chang Christopher J. , Paton Robert S. , Dong Yuyang 
Published: September 2024

AbstractOrganoboron compounds are widely utilized in organic synthesis for their diverse reactivity, modular preparation, and stability compared to other classes of organometallic reagents. While organoboron species are commonly employed as nucleophiles in cross‐coupling reactions, their potential as racemic building blocks in enantioconvergent transformations remains largely untapped. Herein, we demonstrate the direct utilization of alkylboronic pinacol esters in intermolecular enantioconvergent transformations. Specifically, this work describes the development and mechanistic study of an enantioconvergent deborylative cyanation enabled by Cu catalysis. This method imparts a high degree of enantioselectivity and tolerates a wide range of common functional groups and heterocycles. The reaction is proposed to proceed through a radical‐relay mechanism. Aniline‐assisted homolysis of the carbon–boron bond results in prochiral alkyl radicals that are functionalized by in situ generated Cu(II)(CN)2 species in an enantioselective fashion. The Cu(II)(CN)2 intermediate was characterized by electron paramagnetic resonance (EPR) spectroscopy, and its electronic structure was probed using density functional theory (DFT) calculations. Computational studies were carried out to corroborate the proposed radical‐relay mechanism.
Ultra‐Narrow Alkane Product Distribution in Polyethylene Waste Hydrocracking by Zeolite Micro‐Mesopore Diffusion Optimization
Authors: Wang Shuai , Wang Weichen , Chu Mingyu , Gao Daowei , Wang Yong , Lv Yipin , Wang Rongyao , Song Lianghao , Zhao Huaiqing , Chen Jinxing , Chen Guozhu 
Published: September 2024

AbstractPlastic pollution poses a pressing environmental challenge in modern society. Chemical catalytic conversion has emerged as a promising solution for upgrading waste plastics into valuable liquid alkanes and other high value products. However, the current methods yield mixed products with a wide carbon distribution. To address this challenge, we present a bifunctional catalytic system consisting of β zeolite mixed hierarchical Pt@Hie‐TS‐1, designed for the conversion of low‐density polyethylene (LDPE) into liquid alkanes. This system achieves a 94.0 % yield of liquid alkane, with 84.8 % of C5−C7 light alkanes. Combined with in situ FTIR and molecular dynamics simulation, the shape‐selective mechanisms is elucidated, which ensures that only olefins of the appropriate size can diffuse to the encapsulated Pt sites within the zeolite for hydrogenation, resulting in an ultra‐narrow product distribution. Furthermore, by optimizing the micro‐mesopores of Pt@Hie‐TS‐1, the scaling relationship between the pore structure and the conversion/selectivity is identified. The rapid diffusion of olefins within these micro‐mesopores significantly enhances the catalytic efficiency. Our findings contribute to the design of efficient catalysts for plastic waste valorization.