bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demonstration of 11–21‐Membered Intramolecular Sulfonium Ylides: Regio‐ and Diastereoselective Synthesis of Spiro‐Oxindole‐Incorporated Macrocycles
Authors: Muthusamy Sengodagounder , Selvaraj Karuppu , Suresh Eringathodi 
Published: March 2016

AbstractAn expeditious and convenient method for the generation of 11–21‐membered intramolecular macrocyclic sulfonium ylides using catalytic Rh2(OAc)4 is presented. Using this approach, a wide variety of sulfur‐macrocycles incorporating the oxindole unit were produced in good yields and with high diastereoselectivity. Interestingly, tetracyclic macrocycles were also attained in good yields and with good regioselectivity using the disclosed sulfonium ylides. Ring‐opening reactions of tetracyclic macrocycles were also demonstrated.
Electrochemical Study of a CuO–Carbon Conversion Anode in Ionic Liquid Electrolyte for Application in Li‐Ion Batteries
Authors: Verrelli Roberta , Laszczynski Nina , Passerini Stefano , Hassoun Jusef 
Published: March 2016

AbstractA CuO–Carbon anode storing lithium through a conversion mechanism is electrochemically studied in cells employing Pyr14TFSI–LiTFSI electrolyte [Pyr14: N‐butyl‐N‐methylpyrrolidinium], [TFSI: bis(trifluoromethanesulfonyl) imide]. The electrode delivers a specific capacity as high as 580 mAh g−1 with a coulombic efficiency exceeding 98 %. The combination of CuO–carbon with a high‐voltage LiNi0.5Mn1.5O4 cathode in the ionic liquid electrolyte produces a Li‐ion battery with an average operating voltage of 3 V and specific capacity of approximately 120 mAh g−1. The cell, employing easily‐prepared electrodes and a safe ionic liquid electrolyte, represents a good candidate for use in sustainable power sources.
Rapid screening of Alternaria mycotoxins using MALDI‐TOF mass spectrometry
Authors: Sivagnanam Kumaran , Komatsu Emy , Rampitsch Christoph , Perreault Hélène , Gräfenhan Tom 
Published: March 2016

AbstractBACKGROUNDMembers of the Alternaria genus produce various toxins whose occurrence in agricultural commodities is a major concern for humans and the environment. The present study developed a simple and efficient matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) method for the rapid detection of Alternaria toxins.RESULTSA new method for the detection of alternariol (AOH), alternariol monomethyl ether (AME) and tentoxin (TEN) by MALDI‐TOF MS was developed. Different solid phase extraction (SPE) clean‐up methods were tried to optimize the purification of wheat matrix, and an optimal extraction method was designed to recover the three Alternaria toxins. In addition, various MALDI matrices were examined and α‐cyano‐4‐hydroxycinnamic acid (CHCA) matrix gave good repeatability for all three Alternaria toxins.CONCLUSIONThis is the first study to report the detection of three important Alternaria toxins concurrently using MALDI‐TOF MS and opens up the possibility of rapid screening of Alternaria toxins in several other cereals and food products. © 2016 Her Majesty the Queen in Right of Canada Journal of the Science of Food and Agriculture © 2016 Society of Chemical Industry
Marketing Relationships in the New Millennium B2B Sector
Authors: Ndubisi Nelson Oly , Nataraajan Rajan 
Published: March 2016

ABSTRACTMarketing relationships have been touted as an appropriate response to the challenges of the new millennium business environment. An organization that has honed the skill of managing knowledge can respond successfully to the challenges of the new economy. For example, by forging strong and long‐lasting relationships with suppliers and distributors, manufacturers can ensure a stable and sufficient flow of quality products in a timely manner at competitive prices. By doing the same, service providers can ensure not only a wider coverage and greater brand awareness, but also that quality support services are available to both internal and external customers of the firm. This article briefly discusses the role of marketing relationships and relationship marketing in the new millennium business environment and the contributions of Psychology & Marketing to the marketing relationships/relationship marketing discourse. It also introduces the contributions to this special edition and suggests some future research directions.
B2B: A Paradigm Shift from Economic Exchange to Behavioral Theory: A Quest for Better Explanations and Predictions
Authors: LaPlaca Peter , da Silva Rui Vinhas 
Published: March 2016

ABSTRACTThe development of industrial marketing theory has been largely characterized by descriptive approaches in the scrutiny of B2B marketing phenomena. In its pursuit for scientific legitimacy and credibility to academics and practitioners alike, research into B2B relationships as a subject of scientific enquiry will need to seriously engage into what can be termed a true paradigm shift, one that advances discovery in this area from sheer descriptive analysis and reporting to the development of explanatory schemata and theoretical frameworks of a kind that allow for more accurate prediction of underlying B2B phenomena. In doing so, theoreticians and practitioners alike will be better equipped to understand both current and emerging issues at hand as well as their implications to organizations across any geography, cultural context, or business situation. Should this be attained with some degree of success, it will mean a reduction in ambiguity accruing to the decision making of individuals in organizations, and thus a significant contribution to the overriding objective of corporate strategic planning and correspondent resource allocation.
Relational Governance Mechanisms and Uncertainties in Nonownership Services
Authors: Ndubisi Nelson Oly , Ehret Michael , Wirtz Jochen 
Published: March 2016

ABSTRACTEntrepreneurs, managers, and consumers are attracted by the promise of nonownership services in the sharing economy—to enjoy benefits of assets without bearing the costs and downsides of ownership. Firms using nonownership contracts aim to transform uncertainties of clients (e.g., unpredictable changes in value of that asset, unforeseen costs such as repairs, or even black swan events) into business opportunities for providers. In many cases, the reality is that nonownership does not live up to the promised value propositions (as present in the struggle of companies such as Uber, BP, or the entire Biopharma industry) to exploit the potential of nonownership. This paper unveils the underlying paradox of nonownership, which aims at a smart allocation of uncertainty upsides and downsides between providers and clients. It identifies the potential of relational governance mechanisms to handle the uncertainty challenges apparent in nonownership. Further, it presents a pioneering case study of Rolls‐Royce airplane engines, which unveils the contribution of relational governance in unfolding the economic benefits of nonownership.
The Use of Procedural Fairness in Electronic Reverse Auctions to Enhance Relationship Quality
Authors: Muylle Steve , Standaert Willem 
Published: March 2016

ABSTRACTIn this study, the use of procedural fairness by a buying organization in an electronic reverse auction (ERA) is examined. Drawing on the literature, a conceptual model is developed that relates procedural fairness to two key ERA outcomes: relationship quality and quality of the offering. The hypothesized relationships between procedural fairness and quality outcomes are empirically tested through a global field study with 179 procurement professionals in multinational companies, and explored through a supporting field study with 31 sales professionals from supplier firms. The results show that the use of procedural fairness by a buying organization is positively related to relationship quality and quality of the offering, without jeopardizing price savings. In addition, the positive association between procedural fairness and relationship quality is found to increase in the case of a repeat auction. This study contributes to the relationship marketing literature by examining how procedural fairness can mitigate relationship quality concerns in ERA use by buying organizations.
Gastrostomy Complications in Pediatric Cancer Patients: A Retrospective Single‐Institution Review
Authors: Fernandez‐Pineda Israel , Sandoval John A. , Jones Reagan M. , Boateng Nana , Wu Jianrong , Rao Bhaskar N. , Davidoff Andrew M. , Shochat Stephen J. 
Published: March 2016

BackgroundComplications in pediatric cancer patients after a gastrostomy (GT) placement have not been widely investigated. We aimed to evaluate the complication rate and nature of complications in this specific population.ProcedureMedical records of pediatric cancer patients having a GT placed at our institution from 1998 to 2013 were retrospectively reviewed. Variables analyzed included gender, age, diagnosis, surgical procedure, GT device, duration of GT usage, absolute neutrophil count (ANC) level at surgery, and complications.ResultsOne hundred seventy‐one patients (92 males, 79 females), median age of 6 years (range, 0.2–21), who underwent 181 procedures (110 open, 59 endoscopic, and 12 laparoscopic) were identified. Diagnosis included central nervous system tumor (n = 101), solid tumor (n = 45), and leukemia/lymphoma (n = 25). A GT tube was used in 139 procedures and a GT button in 42. Median ANC level at procedure was 3,300/mm3 (range, 0–38,988). Median duration of GT usage was 8 months (range, 0.2–142). One hundred seventy‐seven complications occurred in 106 patients (61.9%) and were categorized as perioperative (<1 month after surgery, 20.3%) and late (>1 month after surgery, 79.7%). Major complications included 42 (23.7%) GT site infections and four (2.2%) intrabdominal complications. The most common minor complication was granulation tissue (28.8%). Younger age at procedure was associated with complications (P = 0.048) and an open technique was associated with GT site infection (P = 0.003). No statistical significance was observed between complications and gender, diagnosis, GT device, duration of GT usage, and ANC at procedure.ConclusionsYounger patients were more likely to have complications, and GT site infections were more common after open GT procedures.
MALDI SpiralTOF high‐resolution mass spectrometry and Kendrick mass defect analysis applied to the characterization of poly(ethylene‐co‐vinyl acetate) copolymers
Authors: Fouquet Thierry , Nakamura Sayaka , Sato Hiroaki 
Published: March 2016

RationalePoly(ethylene‐co‐vinyl acetate) copolymers – usually referred to as EVA – are first class industrial polymers used for applications ranging from padding to photovoltaics as encapsulant for the silicon solar cells. Various techniques have been used for their characterization but the analysis of intact EVA chains using mass spectrometry (MS) has not been reported so far.MethodsThree copolymers containing 18, 25 and 40 wt% vinyl acetate (VA) have been characterized using an off‐line coupling of size‐exclusion chromatography (SEC) and matrix‐assisted laser desorption/ionization (MALDI) spiral‐time‐of‐flight (TOF) high‐resolution mass spectrometry (HRMS). The representativeness of those results for the entire samples has been checked using 13C NMR spectroscopy. Lastly, Kendrick mass defect analysis has been proposed as an alternative and user‐friendly data treatment method.ResultsThe shortest chains isolated by SEC fractionation and mass‐analyzed by HRMS have been thoroughly described in terms of end‐groups (found to be hydrogens) and co‐monomeric composition. The VA content was successfully derived from the peak assignments in MS spectra for the EVA 40 wt% and 25 wt% while it tended to be overestimated for the latest EVA 18 wt% (increasing poly(ethylene) character). Similar results have been found using a faster data treatment method relying on the Kendrick mass defect analysis of the MS data.ConclusionsEVA low molecular weight intact oligomers have been extensively characterized by MS for the first time and the structural features confidently extended to the full sample according to NMR data. The Kendrick mass analysis finally constituted an efficient method for a fast evaluation of their VA content with no need for manual assignment. © 2016 The Authors. Rapid Communications in Mass Spectrometry Published by John Wiley & Sons Ltd.
Research in the Rehabilitation Unit Presents Challenges to Nurse Researchers
Authors: Rose Mary Ann , Neil Janice A. , Castles Ricky , Pokorny Marie , Watkins Frank , Hand Mark 
Published: March 2016

Abstract

Purpose:
Gathering data from patients on a rehabilitation unit poses challenges for nurse researchers.

Design:
A case study is presented that describes ways the researchers attempted to meet these challenges while conducting their study.

Methods:
The case study presents the approaches that the investigators took to undertake the study and then described the ways in which these approaches could have been improved.

Findings:
Their successes and failures are described.

Conclusions:
Suggestions are made for future investigators.

Clinical Relevance:
Clinical nursing research is required to develop an evidence base for practice in the rehabilitation unit. An analysis of the challenges and possible methods of overcoming these challenges is useful to both future investigators and nurses in practice to insure that studies can be carried out effectively.
Phase I study of IMGN901, a CD56-targeting antibody-drug conjugate, in patients with CD56-positive solid tumors
Authors: Shah Manisha H. , Lorigan Paul , O’Brien Mary E. R. , Fossella Frank V. , Moore Kathleen N. , Bhatia Shailender , Kirby Maurice , Woll Penella J. 
Published: March 2016

SummaryBackground IMGN901 is a CD56-targeting antibody-drug conjugate designed for tumor-selective delivery of the cytotoxic maytansinoid DM1. This phase 1 study investigated the safety, tolerability, pharmacokinetics, and preliminary activity of IMGN901 in patients with CD56-expressing solid tumors. Methods Patients were enrolled in cohorts of escalating IMGN901 doses, administered intravenously, on 3 consecutive days every 21 days. A dose-expansion phase accrued patients with small cell lung cancer (SCLC), Merkel cell carcinoma (MCC), or ovarian cancer. Results Fifty-two patients were treated at doses escalating from 4 to 94 mg/m2/day. The maximum tolerated dose (MTD) was determined to be 75 mg/m2. Dose-limiting toxicities included fatigue, neuropathy, headache or meningitis-like symptoms, chest pain, dyspnea, and myalgias. In the dose-expansion phase (n = 45), seven patients received 75 mg/m2 and 38 received 60 mg/m2 for up to 21 cycles. The recommended phase 2 dose (RP2D) was established at 60 mg/m2 during dose expansion. Overall, treatment-emergent adverse events (TEAEs) were experienced by 96.9 % of all patients, the majority of which were Grade 1 or 2. The most commonly reported Grade 3 or 4 TEAEs were hyponatremia and dyspnea (each 8.2 %). Responses included 1 complete response (CR), 1 clinical CR, and 1 unconfirmed partial response (PR) in MCC; and 1 unconfirmed PR in SCLC. Stable disease was seen for 25 % of all evaluable patients who received doses ≥60 mg/m2. Conclusions The RP2D for IMGN901 of 60 mg/m2 administered for 3 consecutive days every 3 weeks was associated with an acceptable tolerability profile. Objective responses were observed in patients with advanced CD56+ cancers.
The effect of airplane noise on frogs: a case study on the Critically Endangered Pickersgill's reed frog (Hyperolius pickersgilli)
Authors: Kruger Donnavan J. D. , Du Preez Louis H. 
Published: March 2016

AbstractSpecies communicating acoustically may develop behavioral responses that aid them to transmit information and overcome signal masking in habitats disturbed by anthropogenic noise. Although many studies have concentrated on road traffic noise, very few studies mentioned effects of low flying airplane flyby noise on the vocal behavior of frogs. We studied the Critically Endangered Pickersgill's Reed frog (Hyperolius pickersgilli) native to the eastern coastal regions of South Africa as a case study. In order to evaluate the call of H. pickersgilli, we compared a site with high levels of airplane flyby noise to a reference site without any airplane activity. Our results show that H. pickersgilli males made changes in both temporal and spectral properties of their call. Males call significantly more during and after an airplane flyby in relation to the call rate before the noise stimulus, but resumed normal call rhythms when measurements were taken 15 min after overflight. We found that males call at higher mean dominant frequencies (df difference = 161.4 Hz, P < 0.05) when exposed to high‐intensity airplane flyby noise. In comparison with call rate 5 min before the airplane flyby, males called 12 % more during and 18 % more after the airplane flyby. Although changes in the spectral and temporal properties of the call of H. pickersgilli were observed, this species was actively calling for much longer than any other local species. This is the first study from Africa to report effects of anthropogenic noise on anuran communication.
CHEN WEI 陳偉 (ED.), QIN JIANDU HEJI 秦簡牘合集 [CORPUS OF QIN DOCUMENTS WRITTEN ON BAMBOO AND WOOD]: A REVIEW ARTICLE
Authors: Venture Olivier 
Published: March 2016

AbstractThe Qin jiandu heji 秦簡牘合集 [Corpus of Qin documents written on bamboo and wood] is the result of a long-term teamwork and collaboration project, directed by Professor Chen Wei 陳偉 of Wuhan University. This publication provides a new, updated edition of seven collections of Qin documents, including those from Shuihudi 睡虎地 (Tomb 4 and 11), Longgang 龍崗 (Tomb 6), Haojiaping 郝家坪 (Tomb 50), Zhoujiatai 周家臺 (Tomb 30), Yueshan 嶽山 (Tomb 36), and Fangmatan 放馬灘 (Tomb 1). Although former editions have not become entirely useless for the various reasons evoked in this article, Qin jiandu heji should now be considered the new standard edition for any serious academic research on those materials.
Development of the Source Reconstruction System by Combining Sound Source Localization and Time Reversal Method
Authors: Lin S.-C. , Too G.-P. , Tu C.-W. 
Published: March 2016

AbstractThis study explored the target sound source location at unknown situation and processed the received signal to determine the location of the target, including the reconstructed signal of source immediately. In this paper, it used triangulation sound sources localization and time reversal method (TRM) to reconstruct the source signals. The purpose is to use a sound source localization method with a simple device to quickly locate the position of the sound source. This method uses the microphone array to measure signal from the target sound source. Then, the sound source location is calculated and is indicated by Cartesian coordinates. The sound source location is then used to evaluate free field impulse response function which can replace the impulse response function used in time-reversal method. This process reduces the computation time greatly which makes possible for a real time source localization and source signal separation.
CLASSIFICATION THEORY FOR ACCESSIBLE CATEGORIES
Authors: LIEBERMAN M. , ROSICKÝ J. 
Published: March 2016

AbstractWe show that a number of results on abstract elementary classes (AECs) hold in accessible categories with concrete directed colimits. In particular, we prove a generalization of a recent result of Boney on tameness under a large cardinal assumption. We also show that such categories support a robust version of the Ehrenfeucht–Mostowski construction. This analysis has the added benefit of producing a purely language-free characterization of AECs, and highlights the precise role played by the coherence axiom.
QUOTIENTS OF STRONGLY PROPER FORCINGS AND GUESSING MODELS
Authors: COX SEAN , KRUEGER JOHN 
Published: March 2016

AbstractWe prove that a wide class of strongly proper forcing posets have quotients with strong properties. Specifically, we prove that quotients of forcing posets which have universal strongly generic conditions on a stationary set of models by certain nice regular suborders satisfy the ω1-approximation property. We prove that the existence of stationarily many ω1-guessing models in Pω2(H(θ)), for sufficiently large cardinals θ, is consistent with the continuum being arbitrarily large, solving a problem of Viale and Weiss [13].
Geographic ranges of genera and their constituent species: structure, evolutionary dynamics, and extinction resistance
Authors: Foote Michael , Ritterbush Kathleen A. , Miller Arnold I. 
Published: March 2016

AbstractWe explore the relationships among the geographic ranges of genera, the ranges and positions of their constituent species, and the number of species they contain, considering variation among coeval genera and changes within genera over time. Measuring range size as the maximal distance, or extent, between occurrences within a taxon, we find that the range of the most widespread species is a good predictor of the range of the genus, and that the number of species is a better predictor still. This analysis is complicated by a forced correlation: the range of a genus must be at least as large as that of each of its constituent species. We therefore focus on a second measure of range, the mean squared distance, or dispersion, of occurrences from the geographic centroid, which, by analogy to the analysis of variance, allows the total dispersion of a genus to be compared to the mean within-species dispersion and the dispersion among species centroids. We find that among-species dispersion is the principal determinant of genus dispersion. Within-species dispersion also plays a major role. The role of species richness is relatively small. Our results are not artifacts of temporal variation in the geographic breadth of sampled data. The relationship between changes in genus dispersion and changes in within- and among-species dispersion shows a symmetry, being similar in cases when the genus range is expanding and when it is contracting. We also show that genera with greater dispersion have greater extinction resistance, but that within- and among-species dispersion are not demonstrable predictors of survival once the dispersion of the genus is accounted for. Thus it is the range of the genus, rather than how it is attained, that is most relevant to its fate. Species richness is also a clear predictor of survival, beyond its effects on geographic range.
A case-control study to identify risk factors for acute salmonellosis in New Zealand dairy herds, 2011–2012
Authors: STEVENSON M. A. , MORGAN P. L. , SANHUEZA J. , OAKLEY G. E. , BATEMAN R. S. , McFADDEN A. , MacPHERSON N. , OWEN K. L. , BURTON L. , WALSH S. , WESTON J. , MARCHANT R. 
Published: March 2016

SUMMARYIn late 2011 the New Zealand Ministry for Primary Industries reported an increase in confirmed laboratory diagnoses of salmonellosis in dairy herds. To identify risk factors for herd-level outbreaks of salmonellosis we conducted a case-control study of New Zealand dairy herds in 2011–2012. In a multivariable analysis, use of continuous feed troughs [adjusted odds ratio (aOR) 6·2, 95% confidence interval (CI) 2·0–20], use of pelletized magnesium supplements (aOR 10, 95% CI 3·3–33) and use of palm kernel meal as a supplementary feed (aOR 8·7, 95% CI 2·5–30) were positively associated with a herd-level outbreak of salmonellosis between 1 July 2011 and 31 January 2012. We conclude that supplementary feeds used on dairy farms (regardless of type) need to be stored and handled appropriately to reduce the likelihood of bacterial contamination, particularly from birds and rodents. Magnesium supplementation in the pelletized form played a role in triggering outbreaks of acute salmonellosis in New Zealand dairy herds in 2011–2012.