bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new record of Xiphinema dentatum Sturhan, 1978 and description of X. paradentatum sp. n. (Nematoda: Dorylaimida) from Serbia
Authors: Barsi László , Fanelli Elena , De Luca Francesca 
Published: September 2017

A population of Xiphinema dentatum, found in a new locality in Serbia, is briefly described and illustrated. Xiphinema paradentatum sp. n. is described and illustrated. It is a parthenogenetic species characterised by its medium to moderately long body (3.71-5.02 mm), open C-shaped when heat-relaxed, lip region frontally almost flattened, laterally rounded and separated from the rest of the body by a weak depression; a moderately long odontostyle (147-166 μm), guide ring located at 137-153 μm from anterior end; two equally developed genital tracts having a pseudo-Z-organ in uterus in the form of several irregular angular sclerotised bodies – apophyses located in the vicinity of the pars dilatata uteri and devoid of spines; tail broadly and symmetrically rounded, and four juvenile developmental stages. Molecular characterisation using the ribosomal ITS and the D2-D3 expansion domains of the 28S rRNA gene was done and maximum likelihood analysis was used to reconstruct the phylogenetic relationships of X. dentatum and X. paradentatum sp. n. from Serbia with other longidorids.
Feasibility of a home-based exercise intervention with remote guidance for patients with stable grade II and III gliomas: a pilot randomized controlled trial
Authors: Gehring Karin , Kloek Corelien JJ , Aaronson Neil K , Janssen Kasper W , Jones Lee W , Sitskoorn Margriet M , Stuiver Martijn M 
Published: September 2017

Objective: In this pilot study, we investigated the feasibility of a home-based, remotely guided exercise intervention for patients with gliomas. Design: Pilot randomized controlled trial (RCT) with randomization (2:1) to exercise or control group. Subjects: Patients with stable grade II and III gliomas. Intervention: The six-month intervention included three home-based exercise sessions per week at 60%–85% of maximum heart rate. Participants wore heart rate monitors connected to an online platform to record activities that were monitored weekly by the physiotherapist. Main measures: Accrual, attrition, adherence, safety, satisfaction, patient-reported physical activity, VO2 peak (by maximal cardiopulmonary exercise testing) and body mass index (BMI) at baseline and at six-month follow-up. Results: In all, 34 of 136 eligible patients (25%) were randomized to exercise training ( N = 23) or the control group ( N = 11), of whom 19 and 9, respectively, underwent follow-up. Mean adherence to prescribed sessions was 79%. Patients’ experiences were positive. There were no adverse events. Compared to the control group, the exercise group showed larger improvements in absolute VO2 peak (+158.9 mL/min; 95% CI: −44.8 to 362.5) and BMI (−0.3 kg/m²; 95% CI: −0.9 to 0.2). The median increase in physical activity was 1489 metabolic equivalent of task (MET) minutes higher in the exercise group. The most reported reasons for non-participation were lack of motivation or time. Conclusion: This innovative and intensive home-based exercise intervention was feasible in a small subset of patients with stable gliomas who were interested in exercising. The observed effects suggest that the programme may improve cardiorespiratory fitness. These results support the need for large-scale trials of exercise interventions in brain tumour patients.
MRI assessment of pituitary iron accumulation by using pituitary-R2 in β-thalassemia patients
Authors: Bozdağ Mustafa , Bayraktaroğlu Selen , Aydınok Yeşim , Çallı Mehmet Cem 
Published: September 2017

Background Patients with thalassemia major (TM) require repeated blood transfusions, which leads to accumulation of iron in a wide variety of tissues. Accumulation of iron in the pituitary gland can lead to irreversible hypogonadotropic hypogonadism (HH) in this group of patients. Purpose To investigate the reliability of pituitary-R2 as a marker to estimate the extent of pituitary iron load by comparing the pituitary magnetic resonance imaging (MRI) findings with hepatic iron load and serum ferritin levels. Material and Methods A total of 38 β-TM patients were classified into HH (group A, n = 18) and non-HH (group B, n = 17) groups. A third group, group C, consisted of 17 healthy participants. Each participant underwent 1.5-T MRI examinations. Pituitary gland heights (PGH), pituitary-R2 values, and liver-R2 values were measured by using multi-echo spin-echo sequences. Results Pituitary-R2 values were significantly higher in group A compared with group B ( P < 0.05). A positive correlation was detected between the pituitary-R2 values and serum ferritin levels in TM patients ( P < 0.01). A threshold value of 14.1 Hz for pituitary-R2 was found to give a high specificity and sensitivity in distinguishing the TM patients with HH from those with normal pituitary functions. PGH measurements were significantly lower in group A compared with group B ( P < 0.05). Conclusion MRI-assessed pituitary-R2 seems to be a reliable marker for differentiating the TM patients with normal pituitary function from those with secondary hypogonadism due to iron toxicity.
MRI evaluation of ligaments and tendons of foot arch in talar dome osteochondral lesions
Authors: Koç Ali , Karabiyik Özgür 
Published: September 2017

Background There are no publications in literature describing an association between disorders of the ligaments and tendons supporting the foot arch and osteochondral lesions of the talus (OCLT). We believe there may be a correlation between the damage of these structures. Purpose To investigate the pathologies of main ligaments and tendons that support the foot arch in sprained ankles, by reviewing magnetic resonance imaging (MRI) studies and comparing the results in two groups of patients, with and without OCLT. Material and Methods MR images from 316 patients examined in the orthopedic clinic for ankle sprain were evaluated for pathologic findings of the plantar fascia, short and long plantar ligaments, spring ligament, sinus tarsi, and ankle tendons supporting the foot arch. Findings were compared between two groups of patients: 158 patients with OCLT and 158 patients without OCLT. Results Plantar fascia, short plantar ligament, and spring ligament abnormalities were seen in 50 (31.6%), 28 (17.7%), and 60 (38%) patients with OCLT, and in nine (5.6%), three (1.9%), and 18 (11.4%) patients without OCLT, respectively ( P < 0.05). Sinus tarsi and tendon abnormalities were seen in 11 (6.7%) and nine (5.7%) patients with OCLT, and in eight (5%) and eight (5%) patients without OCLT, respectively ( P > 0.05). Two or more associated abnormalities were present in 50 (31.6%) patients with OCLT and in 11 (6.7%) without OCLT ( P < 0.05). Conclusion Plantar fascia, short plantar ligament, and spring ligament abnormalities were commonly seen in patients with OCLT on MRI, while sinus tarsi and tendon abnormalities were not. Concomitant pathologies have an increased incidence in patients with OCLT.
Cytoprotective activated protein C averts Nlrp3 inflammasome–induced ischemia-reperfusion injury via mTORC1 inhibition
Authors: Nazir Sumra , Gadi Ihsan , Al-Dabet Moh’d Mohanad , Elwakiel Ahmed , Kohli Shrey , Ghosh Sanchita , Manoharan Jayakumar , Ranjan Satish , Bock Fabian , Braun-Dullaeus Ruediger C. , Esmon Charles T. , Huber Tobias B. , Camerer Eric , Dockendorff Chris , Griffin John H. , Isermann Berend , Shahzad Khurrum 
Published: September 2017

Key Points
aPC protects from myocardial and renal IRIs by restricting mTORC1-mediated activation of the Nlrp3 inflammasome. Nlrp3 inflammasome suppression by aPC is independent of its anticoagulant effect, depends on PAR-1, and can be mimicked by parmodulin-2.
Comparison of mastery learning model and WhatsApp assisted learning in teaching psychomotor skills: A triangulation study<p>Psikomotor beceri öğretiminde tam öğrenme modeli ve WhatsApp destekli öğretim yöntemlerinin karşılaştırılması: Bir triangülasyon çalışması
Authors: Turaç Nilay , Çalışkan Nurcan , Gülnar Emel 
Published: September 2017

Aim: The purpose of this study is to comparison the effect of mastery learning model and WhatsApp assisted learning on teaching psychomotor skills.Material and method: The study was conducted as a triangulation study between 8 March- 16 December, 2016. The students were divided into two groups in a randomized way. One of the groups (n:30) was instructed with mastery learning model concerning the skill of inserting nasogastric catheter; whereas, the other group (n:30) was assisted through WhatsApp. While the quantitative data were collected by using “Nasogastric Catheter Insertion Skill Check List”, the qualitative data were collected through the focus group interview. The data were analyzed by using number, percentage, student-t test, and descriptive analysis method.Results: The skill mean scores for the students learning the skill of nasogastric catheter insertion through WhatsApp assistance were (26.27±5.70) significantly higher than the mean scores of those learning this skill with mastery learning model (22.07±4.06). However, it was found that students learning with mastery learning experienced less stress during the practice. Conclusion: It is considered that in teaching of psychomotor skills, the use of means of social media such as WhatsApp as a support to the courses together with the mastery learning model would be beneficial. Extended English abstract is in the end of PDF (TURKISH) file. ÖzetAmaç: Araştırma, tam öğrenme modeli ile WhatsApp destekli öğretimin psikomotor beceri öğretimine etkilerinin karşılaştırılması [sbf1] amacıyla yapılmıştır.Materyal Metot: Araştırma, Mart- Aralık 2016 tarihleri arasında triangülasyon çalışması olarak yapılmıştır. Öğrenciler, randomize olarak iki gruba ayrılmıştır. Bir gruba (n:30), nazogastrik sonda takma becerisiyle ilgili tam öğrenme modeliyle destek verilirken diğer gruba (n:30) WhatsApp ile destek verilmiştir. “Nazogastrik Sonda Takma Becerisi Kontrol Listesi” kullanılarak nicel veriler, odak grup görüşmesiyle nitel veriler toplanmıştır. Veriler sayı, yüzdelik, student-t testi ve betimsel analiz yöntemiyle analiz edilmiştir.Bulgular: Nazogastrik sonda takma becerisini WhatsApp desteğiyle öğrenen öğrencilerin beceri puan ortalamaları (26.27±5.70), tam öğrenme modeliyle öğrenen öğrencilerin ortalamalarından (22.07±4.06) anlamlı derecede yüksek bulunmuştur. Ancak, tam öğrenme modeliyle öğrenen öğrencilerin uygulamada daha az stres yaşadıkları saptanmıştır. Sonuç:WhatsApp gibi sosyal medya araçlarının, beceri eğitiminde tam öğrenme modeliyle birlikte derslere destek olarak kullanılmasının yararlı olacağı düşünülmektedir.// Annotate Highlight // Annotate Highlight // Annotate Highlight // Annotate Highlight // Annotate Highlight // Annotate Highlight // Annotate Highlight // Annotate Highlight
Pengaruh Desa Wisata Kampoeng Batik Laweyan terhadap Fungsi Permukiman di Kelurahan Laweyan Kota Surakarta
Authors: Mangedaby Eva Artmey , Setioko Bambang , Sari Suzanna Ratih 
Published: September 2017

Kota Surakarta merupakan salah satu sentra produksi batik di Jawa Tengah yang terkenal karena batik berkualitas, salah satu nya adalah sentra batik yang berada di Kampung Batik Laweyan. Kampung batik yang terletak di Kelurahan Laweyan ini tengah marak di Indonesia karena merupakan salah satu daerah tujuan wisata. Sebagai kampung batik yang saat ini tengah popular, membuat kawasan permukiman di Kelurahan Laweyan juga mengalami perubahan. Hal ini terlihat dari bentuk dan tata ruang rumah itu sendiri. Perubahan ini tidak hanya terjadi pada kampung batik Laweyan saja tetapi satu Kelurahan Laweyan, sehingga mengakibatkan tidak tersedianya ruang terbuka hijau di Kelurahan Laweyan. Penelitian ini bertujuan untuk mencari pengaruh desa wisata Desa Kampung Batik Laweyan terhadap fungsi permukiman di Kelurahan Laweyan serta untuk menentukan seberapa besar pengaruh desa wisata Kampung Batik Laweyan terhadap fungsi permukiman di Kelurahan Laweyan Kota Surakarta dan bagaimana pengaruhnya. Metode penelitian yang digunakan adalah metode kuantitatif dengan pendekatan korelasi memakai analisis likerts serta analisis skoring berdasarkan asumsi yang sudah ditetapkan kemudian di uji dengan analisa regresi linear berganda menggunakan uji SPSS. Teknik analisis data dalam penelitian ini menggunakan statistik deskriprif untuk mengambil kesimpulan dari sampel yang diuji. Proses penelitian ini melalu tiga tahapan yaitu kompilasi data, pemberian kode variabel dan pengolahan data dengan analisa regresi. Hasil temuan studi yang didapat setelah melalui tahapan-tahapan tersebut adalah desa wisata Kampung Batik Laweyan mempengaruhi fungsi permukiman di Kelurahan Laweyan Kota Surakarta sebesar 81,6% sedangkan sisanya 18,4% dipengaruhi oleh faktor lain diluar model. Pengaruh desa wisata Kampung Batik Laweyan terhadap fungsi permukiman di Kelurahan Laweyan Kota Surakarta adalah dengan berubahnya fungsi permukiman di Kelurahan Laweyan yang dulunya hanya sebagai hunian sekarang berubah menjadi hunian dan tempat usaha, serta penambahan fasilitas pendukung wisata lainnya, selain itu juga terdapat penambahan street furniture yang menjadi ciri khas desa wisata Kampung Batik Laweyan. Sedangkan untuk faktor lain yang memperngaruhi diluar model adalah sejarah kawasan dan perubahan tata guna lahan. Peran stakeholders yang terkait seperti pemerintah, swasta dan masyarakat sangat diperlukan. Pemerintah berperan sebagai pengelola dan fasilitator, swasta sebagai pembantu pelaksana program pemerintah sedangkan masyarakat bisa berpartisipasi dalam pengembangan desa wisata Kampung Batik Laweyan. Kata Kunci: Kampung Batik, Desa Wisata, Permukiman, Fungsi Permukiman
DRUGAS: implantable telemetric system for measuring the portal venous pressure: assembly aspects
Authors: Fischer Roland , Weidenmüller Jens , Görtz Michael , Goettsche Thorsten , Mokwa Wilfried 
Published: September 2017

Abstract
Developing an implantable, telemetric pressure measuring system for venous applications makes a high degree of miniaturization necessary. Thus the influence on the measurement environment is minimized and the risk of thrombosis at small flow blood velocities is decreased. But these systems are limited in terms of accuracy and resolution. The asked system requirements could only be reached by optimising the assembly and encapsulation techniques. To achieve the high degree of miniaturization numerical simulations were performed on the shape and size of the implant and led to the development of a specific metal housing consisting of two main components. A small measuring chamber will be placed into the portal vein and is rigidly fixed to a flat circular part that contains the pressure sensor chip and a transponder board and will be located outside on top of the vein. The main focus of the assembly process was based on a stress-free design and mounting of the components.
Intention recognition for FES in a grasp-and-release task using volitional EMG and inertial sensors
Authors: Salchow Christina , Dorn Andreas , Valtin Markus , Schauer Thomas 
Published: September 2017

Abstract
Functional Electrical Stimulation (FES) facilitates the motor recovery of the hand function after stroke. The integration of biofeedback and other strategies to actively in-volve a patient in the therapy is important for the rehabili-tation progress. We introduce a combined control approach for a FES-driven neuroprosthesis using volitional electromyo-graphy (vEMG) and motion capturing via a novel inertial sensor network for patients that still possess a residual activity in the paralyzed muscles. A real-time vEMG measurement and signal processing in between stimulation pulses has been realized during active FES. Experiments showed that our system allows for quick adaption to individual users.
Determination of EPID convolution kernels for portal imaging using carbon target bremsstrahlung
Authors: Lüdeke Sascha , Wyrwoll Vanessa , Stelljes Tenzin S. , Looe Hui Khee , Harder Dietrich , Poppe Björn 
Published: September 2017

Abstract
Improving the accuracy and reproducibility during patient positioning is of paramount importance. Hence, the goal of this work is to characterize the aspects of image blurring occurring during carbon target bremsstrahlung portal imaging and to assess the applicability of a deconvolution algorithm. Blurring effects involved in this method of portal imaging are electron scattering inside the EPID, geometric blurring due to the photon source size and photon scattering inside the patient. These effects can all be described by convolutions using as the convolutional kernel a Lorentz function, whose FWHM is 2λ. The λ values measured for these effects range from 0.2 mm to 0.45 mm, and an iterative 2D-deconvolution of carbon target portal images was performed accordingly. A significant decrease in the image blurring of test objects has been achieved and confirmed by analyzing the RMTF. However for clinical images, the deconvolution method is presently faced with the problem of the associated increase of image noise.
Polarization sensitive optical coherence tomography utilizing a buffered swept source laser
Authors: Golde Jonas , Kirsten Lars , Koch Edmund 
Published: September 2017

Abstract
We present an approach for polarization sensitive optical coherence tomography (PS-OCT) that solely requires a modification of the light source, a buffered swept source laser. For this purpose a single-mode fiber-based Fourier domain mode locked laser is extended by fourfold buffering with manual fiber polarization controllers to emit alternating sweep polarizations, while the polarization contrast calibration is realized by a high-speed polarimeter. As the introduced setup utilizes standard scanning and detection units, the proposed method is a promising way to enhance various swept source OCT systems by polarization sensitive imaging. Preliminary measurements of a human finger nail with different polarization contrasts demonstrate the feasibility of the concept.
INNOLAB- image guided surgery and therapy lab
Authors: Fritzsche Holger , Boese Axel , Friebe Michael 
Published: September 2017

Abstract
Incremental innovation, something better or cheaper or more effective, is the standard innovation process for medical product development. Disruptive innovation is often not recognized as disruptive, because it very often starts as a simple and easy alternative to existing products with much reduced features and bad performance. Innovation is the invention multiplied with a commercial use, or in other words something that eventually provides a value to a clinical user or patient. To create such innovation not a technology push (technology delivered from a technical need perspective) but rather a pull (by learning and working with the clinical users) is required. Medical technology students need to understand that only through proper observation, procedure know-how and subsequent analysis and evaluation, clinically relevant and affordable innovation can be generated and possibly subsequently used for entrepreneurial ventures. The dedicated laboratory for innovation, research and entrepreneurship- INNOLAB ego.-INKUBATOR IGT (Image Guided Therapies) is financed by the state of Sachsen-Anhalt as part of the European ego.-INKUBATOR program with (EFRE funds) at the university clinic operated by the technical chair for catheter technologies and image guided surgeries. It forms a network node between medicine, research and economics. It teaches students to lead innovation processes, technology transfer to the user and is designed to stimulate the start-up intentions.
Electrical interventricular delay and left ventricular delay in right ventricular pacemaker pacing before upgrading to cardiac resynchronization therapy
Authors: Heinke Matthias , Dannberg Gudrun , Heinke Tobias , Hörth Johannes , Kühnert Helmut 
Published: September 2017

Abstract
Cardiac resynchronization therapy with biventricular pacing is an established therapy for heart failure patients with sinus rhythm, reduced left ventricular ejection fraction and electrical ventricular desynchronization. The aim of the study was to evaluate electrical interventricular delay and left ventricular delay in right ventricular pacemaker pacing before upgrading to cardiac resynchronization therapy. Heart failure patients with right ventricular pacing, DDD pacemaker, DDD defibrillator and 24.5 ± 4.9 % left ventricular ejection fraction were measured by surface ECG and transesophageal bipolar left ventricular ECG before upgrading to cardiac resynchronization therapy. Interventricular and intraventricular desynchronization in right ventricular pacemaker pacing were 228.2 ± 44.8ms QRS duration, 86.5 ± 32.8ms interventricular delay and 94.4 ± 23.8ms left ventricular delay. Cardiac resynchronization therapy was optimized by impedance cardiography. Transesophageal electrical interventricular delay and left ventricular delay in right ventricular pacemaker pacing may be additional useful ventricular desynchronization parameters to improve patient selection for upgrading right ventricular pacemaker pacing to cardiac resynchronization therapy.
Considerations on employing a PMQ-doublet for narrow and broad proton energy distributions
Authors: Rösch Thomas F. , Hilz Peter , Bin Jianhui , Englbrecht Franz , Gao Ying , Haffa Daniel , Hartmann Jens , Herr Sebastian , Lindner Florian H. , Speicher Martin , Würl Matthias , Parodi Katia , Schreiber Jörg 
Published: September 2017

Abstract
We simulated a doublet of permanent magnet quadrupoles (PMQs) to estimate the sensitivity on positioning precision and its impact on the spectral properties of transported protons. The study guided the construction and testing of a focusing setup for laser-accelerated proton bunches with energies between 6 and 10 MeV. Our results shed light on possible applications that may arise from broad input particle spectra.
Planning strategies and practical implementation of the cardiac dose reduction in the left-side breast irradiation with the deep inspiration breath-hold (DIBH) method
Authors: Wagner Linda , Koch Thomas , Fahrig Antje 
Published: September 2017

Abstract
Background: Despite of the use of tangential beam directions during the irradiation of mammary carcinomas, a dose reduction of the heart cannot always be achieved. This is decivise for the increased risk of heart diseases and the associated mortality. Especially affected is the cardiac apex. However, by using respiratory gated treatment techniques, like the deep inspiration breath-hold (DIBH), a dose sparing of this area can be reached.
Material and Methods: The Elekta ABC system was used to control the respiratory stop of early staged breast cancer patients. The treatment planning was implemented by a 3D and VMAT technique. The focus was the optimization of irradiation plans and the evaluation of the respective dose exposure to the heart, the left ventricle and the left anterior descending coronary artery (LAD artery). A planning concept of 28 x 2,25 Gy in the SIB and 28 x 1,8 Gy in the left breast was used.
Results: The results showed that a dose reduction of 30-40% in mean and maximal in all structures is possible by using the VMAT technique in combination with the ABC system. In the case of 3D irradiation planning, a substantial relief can only be seen at the mean dose exposure of approximately 50%. Also, only a maximum dose reduction of 13% could be achieved.
Conclusion: The mean dose reduction was mainly achieved by the increased distance between the heart and the thorax wall. The maximum dose was reduced by the volumentric optimization algortihm of the VMAT and the resulting steeper dose fall-off at the inner thoracic wall. Due to the lack of this optimization and thus the greater dose drop, the maximum dose of the 3D plans could only reduced by 13%.