bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Enantioselective C—H Olefination of α‐Hydroxy and α‐Amino Phenylacetic Acids by Kinetic Resolution.
Authors: Xiao Kai‐Jiong , Chu Ling , Yu Jin‐Quan 
Published: June 2016

AbstractThe first examples of kinetic resolution by a palladium(II)‐catalyzed enantioselective C—H activation and C—C bond formation are described.
ChemInform Abstract: Enantioselective N‐Heterocyclic Carbene Catalysis by the Umpolung of α,β‐Unsaturated Ketones.
Authors: Nakano Yuji , Lupton David W. 
Published: June 2016

AbstractUsing a chiral morpholine‐fused triazolium salt as NHC precatalyst, the first examples for the enantioselective synthesis of 2‐aryl propionates by umpolung of α,β‐unsaturated ketones are presented.
ChemInform Abstract: Asymmetric Transfer Hydrogenation of Ketones with Modified Grubbs′ Metathesis Catalysts: On the Way to a Tandem Process.
Authors: Renom‐Carrasco Marc , Gajewski Piotr , Pignataro Luca , de Vries Johannes G. , Piarulli Umberto , Gennari Cesare , Lefort Laurent 
Published: June 2016

AbstractUpon addition of a chiral amine ligand, an alcohol and a base, the 1st generation Hoveyda—Grubbs catalyst is in situ transformed into an asymmetric transfer hydrogenation catalyst, promoting the enantioselective reduction of acetophenone to 1‐phenylethanol.
ChemInform Abstract: Gold(I)‐Catalyzed Angle Strain Controlled Strategy to Furopyran Derivatives from Propargyl Vinyl Ethers: Insight into the Regioselectivity of Cycloisomerization.
Authors: Jin Shengfei , Jiang Chongguo , Peng Xiaoshi , Shan Chunhui , Cui Shanshan , Niu Yuanyuan , Liu Yang , Lan Yu , Liu Yongxiang , Cheng Maosheng 
Published: June 2016

AbstractThe utility of this method is demonstrated in the synthesis of the mycotoxin isopatulin (IV).
ChemInform Abstract: C—C Bond‐Forming Strategy by Manganese‐Catalyzed Oxidative Ring‐Opening Cyanation and Ethynylation of Cyclobutanol Derivatives.
Authors: Ren Rongguo , Wu Zhen , Xu Yan , Zhu Chen 
Published: June 2016

AbstractA novel and general C—C bond‐forming strategy employing manganese‐catalyzed ring‐opening cyanation or ethynylation of cyclobutanols is described.
ChemInform Abstract: Direct Regioselective γ‐Amination of Enones.
Authors: Chen Xiaohong , Liu Xiaoguang , Mohr Justin T. 
Published: June 2016

AbstractThe regioselective γ‐C—N bond formation occurs with enone substrates through controlled dienolate reactivity toward azodicarboxylate electrophiles, representing the first direct γ‐amination of ketone‐derived dienolates.
ChemInform Abstract: Palladium‐Catalyzed C—H Arylation of α,β‐Unsaturated Imines: Catalyst‐Controlled Synthesis of Enamine and Allylic Amine Derivatives.
Authors: Li Minyan , Gonzalez‐Esguevillas Maria , Berritt Simon , Yang Xiaodong , Bellomo Ana , Walsh Patrick J. 
Published: June 2016

AbstractA remarkable catalyst‐controlled chemo‐ and regioselective α‐ and γ‐arylation of azaallyl anion intermediates is developed.
ChemInform Abstract: Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β‐Fluoroamines by Formal Tandem Hydrodefluorination/Deamination.
Authors: Cuetos Anibal , Garcia‐Ramos Marina , Fischereder Eva‐Maria , Diaz‐Rodriguez Alba , Grogan Gideon , Gotor Vicente , Kroutil Wolfgang , Lavandera Ivan 
Published: June 2016

AbstractA series of racemic β‐fluoroamines is kinetically resolved by a tandem hydrodefluorination/deamination process.
ChemInform Abstract: Visible Light Photoredox Cross‐Coupling of Acyl Chlorides with Potassium Alkoxymethyltrifluoroborates: Synthesis of α‐Alkoxyketones.
Authors: Amani Javad , Sodagar Esmat , Molander Gary A. 
Published: June 2016

AbstractIn the single‐electron‐transfer, photoredox cross‐coupling, various aliphatic and aromatic acyl chlorides are coupled with structurally diverse potassium alkoxymethyltrifluoroborates to produce the corresponding α‐alkoxyketones.
ChemInform Abstract: N‐Iodosuccinimide‐Promoted Cascade Trifunctionalization of Alkynoates: Access to 1,1‐Diiodoalkenes.
Authors: Ni Shengyang , Sha Wanxing , Zhang Lijun , Xie Chen , Mei Haibo , Han Jianlin , Pan Yi 
Published: June 2016

AbstractThe novel cascade strategy for trifunctionalization of an acetylene bond proceeds via a sequence involving iodination, aryl migration, decarboxylation, and a second iodination.
ChemInform Abstract: Rh(II)‐Catalyzed Intramolecular Dearomatizing Annulation of N‐Sulfonyl‐1,2,3‐triazoles: Synthesis of Polycyclic Spiroindolines.
Authors: Bora Pranjal Protim , Luo Zeng‐Liang , Chen Li , Kang Qiang 
Published: June 2016

AbstractAn efficient approach for the synthesis of polycyclic spiroindolines is developed by utilizing Rh(II)‐catalyzed dearomatizing annulation of sulfonyl triazoles.
ChemInform Abstract: α‐Regioselective Asymmetric [3 + 2] Annulations of Morita—Baylis—Hillman Carbonates with Cyclic 1‐Azadienes and Mechanism Elucidation
Authors: Wang Kai‐Kai , Jin Tian , Huang Xin , Ouyang Qin , Du Wei , Chen Ying‐Chun 
Published: June 2016

Abstract31 examples
ChemInform Abstract: Copper‐Catalyzed Preparation of 2‐Aryl‐3‐cyanobenzofurans with Bright Blue Photoluminescence.
Authors: Zhang Lianpeng , Peng Zhixing , Wen Qiaodong , Li Xihui , Lu Ping , Wang Yanguang 
Published: June 2016

AbstractThe cascade synthesis of arylcyanobenzofurans from o‐hydroxybenzaldehydes and arylacetonitriles includes Knoevenagel condensation, cyanide anion transfer, intramolecular nucleophilic addition, and aromatization.
ChemInform Abstract: A Facile Synthesis of Cyano‐Chlorins Related to Chlorophyll from Formyl (Pyro)‐Pheophorbide‐a by a Tandem Transformation of the Aldehyde into a Nitrile Group
Authors: Gao Na , Li Jia‐Zhu , Li Yan‐Long , Wang Zhen , Wang Jin‐Jun 
Published: June 2016

AbstractA facile method to synthesize cyanochlorin from a formyl‐substituted chlorin by oxidation of methyl (pyro)pheophorbide‐a is accomplished.
ChemInform Abstract: Silver‐Mediated Intermolecular 1,2‐Alkylarylation of Styrenes with α‐Carbonyl Alkyl Bromides and Indoles.
Authors: Ouyang Xuan‐Hui , Song Ren‐Jie , Hu Ming , Yang Yuan , Li Jin‐Heng 
Published: June 2016

AbstractThe new radical 1,2‐alkylarylation of styrenes results in two new C—C bonds generated in a single step through a sequence of intermolecular C(sp3)—Br functionalization and C(sp2)—H functionalization across the alkene.
ChemInform Abstract: Convenient Synthesis of Antiproliferative 2,3‐Dihydro‐2,3′‐bisindoles via Dimerization of N‐H Indole Derivatives.
Authors: Guo Tao , Han Shu‐Lei , Liu Ying‐Chao , Liu Yu , Liu Hong‐Min 
Published: June 2016

AbstractThe synthetic utility of title compounds (II) is demonstrated by further transformations, including cross‐coupling reactions or Pd‐catalyzed aromatization to afford bisindoles (III).
ChemInform Abstract: Optically Active 4‐Substituted 5‐Nitropentan‐2‐ones: Valuable Chiral Building Blocks for the Stereocontrolled Construction of Spiro‐Pyrazolone Scaffolds with Five Contiguous Stereogenic Centers.
Authors: Sun Jiao , Jiang Cuiping , Zhou Zhenghong 
Published: June 2016

AbstractIn a first step, pentanone precursors of type (III) are prepared.
ChemInform Abstract: Synthesis of Oxazolidin‐2‐ones by Oxidative Coupling of Isonitriles, Phenyl Vinyl Selenone, and Water.
Authors: Buyck Thomas , Pasche Delphine , Wang Qian , Zhu Jieping 
Published: June 2016

AbstractReaction of alkyl isocyanides, phenyl vinyl selenone, and water in the presence of a catalytic amount of Cs2CO3 affords oxazole derivatives in good yields.
ChemInform Abstract: Assembly of 3‐(Trifluoromethyl)thiochromenes via a Regioselective Trifluoromethylthioarylation of (3‐Arylprop‐2‐ynyl)oxybenzenes with Trifluoromethanesulfanylamide.
Authors: Liu Tong , Qiu Guanyinsheng , Ding Qiuping , Wu Jie 
Published: June 2016

AbstractThe synthesis of title compounds proceeds via electrophilic cyclization and reaction with CF3+ generated in situ by reaction of (II) with BiCl3.
ChemInform Abstract: Synthesis of Polysubstituted 1,2‐Dihydroquinolines and Indoles via Cascade Reactions of Arylamines and Propargylic Alcohols Catalyzed by FeCl3·6H2O.
Authors: Shao Min , Wu Yunjun , Feng Zhijun , Gu Xiaoxia , Wang Shaoyin 
Published: June 2016

AbstractDihydroquinolines are readily accessible from inexpensive starting materials by a iron‐catalyzed Friedel—Crafts‐type reaction/6‐endo‐trig hydroamination cascade.
ChemInform Abstract: 4‐Heterosubstituted Cyclopentenone Antiviral Compounds: Synthesis, Mechanism, and Antiviral Evaluation.
Authors: Mantione Daniele , Aizpuru Olatz Olaizola , Memeo Misal Giuseppe , Bovio Bruna , Quadrelli Paolo 
Published: June 2016

AbstractThe title cyclopentenones are prepared by a typical nucleophilic substitution process of racemic oxocyclopentenyl acetate with uracil, thymine, 6‐chloropurine, and some adenines.
ChemInform Abstract: Modular Approaches to Diversified Soft Lewis Basic Complexants Through Suzuki—Miyaura Cross‐Coupling of Bromoheteroarenes with Organotrifluoroborates.
Authors: Chin Ai Lin , Carrick Jesse D. 
Published: June 2016

AbstractThe Pd‐catalyzed cross‐coupling of bis‐ and tris‐brominated pyridyl‐substituted 1,2,4‐triazines with organotrifluoroborates is used to synthesize a variety of the corresponding organyl substituted derivatives.
ChemInform Abstract: Synthesis and Characterization of a Di‐μ‐oxalato Tetracopper(II) Complex with Tetranucleating Macrocyclic Ligand
Authors: Miyazato Yuji , Asato Eiji , Ohba Masaaki , Wada Tohru 
Published: June 2016

Abstractsynthesis and investigation of structural and magnetic properties of the new tetracopper(II) complex
ChemInform Abstract: Synthesis and Configurations of (‐)‐Furospongin‐1 and (+)‐Dihydrofurospongin‐2.
Authors: Tan Dong‐Xing , Xu Ze‐Jun , Chen Hui‐Jun , Wu Yikang , You Jun 
Published: June 2016

AbstractThe furanoterpenes, furospongin‐1 (I) and dihydrofurospongin‐2 (II), are prepared for the first time using a chiral‐pool‐based sequence.
ChemInform Abstract: Homopetasinic Acid Isolated from Diaporthe sp. Strain 1308‐05.
Authors: Ito Atsushi , Kumagai Ikuya , Maruyama Miku , Maeda Hayato , Tonouchi Akio , Nehira Tatsuo , Kimura Ken‐ichi , Hashimoto Masaru 
Published: June 2016

Abstractisolation, structure determination and biological activities
ChemInform Abstract: Sarglaperoxides A and B, Sesquiterpene—Normonoterpene Conjugates with a Peroxide Bridge from the Seeds of Sarcandra glabra.
Authors: Wang Peng , Li Rui‐Jun , Liu Rui‐Huan , Jian Kai‐Li , Yang Ming‐Hua , Yang Lei , Kong Ling‐Yi , Luo Jun 
Published: June 2016

AbstractSarglaperoxide A (I) demonstrates moderate antibacterial and antiinflammatory activities in vitro.
ChemInform Abstract: Characteristic Steroids from the South China Sea Gorgonian Muricella sibogae and Their Cytotoxicities.
Authors: Zhang Xing‐Wang , Tang Xu‐Li , Liu Bao‐Sheng , Li Ping‐Lin , Li Guo‐Qiang 
Published: June 2016

AbstractOne new secosteroid, Sibogol D (I), and two new steroids, Sibogols E (IIa) and F (IIb), are isolated from the Muricella sibogae along with 21 known steroid‐based natural products.
ChemInform Abstract: Regioselective, Tin‐Free Sulfation of Unprotected Hexopyranosides by Using Phenylboronic Acid
Authors: Fukuhara Kenji , Shimada Naoyuki , Nishino Takashi , Kaji Eisuke , Makino Kazuishi 
Published: June 2016

Abstractfor masking the hydroxy groups and a 2,2,2‐trichloroethyl‐protected sulfurylimidazolium salt as the sulfating reagent
ChemInform Abstract: Synthesis and Separation of Cucurbit[n]urils and Their Derivatives
Authors: Cong Hang , Ni Xing Long , Xiao Xin , Huang Ying , Zhu Qian‐Jiang , Xue Sai‐Feng , Tao Zhu , Lindoy Leonard F. , Wei Gang 
Published: June 2016

AbstractReview: 221 refs.
Impact of fine solids on mined Athabasca oil sands extraction I. Floatability of fine solids
Authors: Zhou Zoe A. , Li Haihong , Chow Ross , Adeyinka Olusola B. , Xu Zhenghe , Masliyah Jacob 
Published: June 2016

AbstractUnderstanding the mechanisms by which fine solids are recovered to bitumen froth during oil sands extraction plays a critical role in minimizing the detrimental effect of fines on bitumen recovery and froth quality. A simple method was presented in this study to distinguish fine solids recovery by water entrainment from that by true flotation. Dispersed air flotation was carried out, using a 1‐L Denver flotation cell, to evaluate flotation behaviours of different sizes and types of fine solids (< 5 μm up to < 40 μm silica, < 5 μm kaolinite clays, and < 44 μm fine solids extracted from oil sands). The results show that dispersed individual fine solids in oil sands slurries could be recovered to the froth by mechanical entrainment, and by true flotation. While the recovery of hydrophilic fine solids decreased with increasing particle sizes by water entrainment, the recovery of hydrophobized fine solids, due to dodecylamine adsorption, increased with increasing particle sizes by true flotation. Fine solids extracted from oil sands behaved differently from pure silica or clays: they adsorbed amine slowly, and responded to flotation slowly. The exact reasons remain to be explored.
Role of Intramolecular Aromatic π–π Interactions in the Self‐Assembly of Di‐l‐Phenylalanine Dipeptide Driven by Intermolecular Interactions: Effect of Alanine Substitution
Authors: Reddy Samala Murali Mohan , Shanmugam Ganesh 
Published: June 2016

AbstractAlthough the role of intermolecular aromatic π–π interactions in the self‐assembly of di‐l‐phenylalanine (l‐Phe‐l‐Phe, FF), a peptide that is known for hierarchical structure, is well established, the influence of intramolecular π–π interactions on the morphology of the self‐assembled structure of FF has not been studied. Herein, the role of intramolecular aromatic π–π interactions is investigated for FF and analogous alanine (Ala)‐containing dipeptides, namely, l‐Phe‐l‐Ala (FA) and l‐Ala‐l‐Phe (AF). The results reveal that these dipeptides not only form self‐assemblies, but also exhibit remarkable differences in structural morphology. The morphological differences between FF and the analogues indicate the importance of intramolecular π–π interactions, and the structural difference between FA and AF demonstrates the crucial role of the nature of intramolecular side‐chain interactions (aromatic–aliphatic or aliphatic–aromatic), in addition to intermolecular interactions, in deciding the final morphology of the self‐assembled structure. The current results emphasise that intramolecular aromatic π–π interaction may not be essential to induce self‐assembly in smaller peptides, and π (aromatic)–alkyl or alkyl–π (aromatic) interactions may be sufficient. This work also illustrates the versatility of aromatic and a combination of aromatic and aliphatic residues in dipeptides in the formation of structurally diverse self‐assembled structures.
Separation of Light Hydrocarbons through Selective Molecular Exclusion by a Microporous Metal–Organic Framework
Authors: Wang Hao , Wang Xin‐Long , Li Jing 
Published: June 2016

Abstract[Zn2(sdc)2(bpe)] (compound 1, sdc=4,4′‐stilbenedicarboxylate, bpe=1,2‐bis(4‐pyridyl)ethane)), a doubly interpenetrated, pillared‐layer microporous metal–organic framework has been solvothermally synthesized and structurally characterized by single‐crystal X‐ray diffraction. The structure features a common Zn2(COO)4 paddle‐wheel building unit. Compound 1 undergoes structural change upon solvent removal. The activated phase (compound 2) displays permanent porosity, excellent thermal/moisture stability, and interesting hydrocarbon adsorption properties. Gas adsorption experiments show that compound 1 selectively adsorbs saturated/unsaturated C2 hydrocarbons but excludes C3 and C4 hydrocarbons at room temperature. We have collected single‐component adsorption isotherms of six light hydrocarbons and calculated adsorption selectivities of various binary hydrocarbon mixtures by ideal adsorbed solution theory (IAST). The results show that compound 1 possesses remarkably high selectivity towards C2 over C3/C4 hydrocarbons and the separation is achieved by selective molecular exclusion.
Adolescent and Family‐focused Cognitive–behavioural Therapy for Paediatric Bipolar Disorders: A Case Series
Authors: Knutsson Jens , Bäckström Beata , Daukantaitė Daiva , Lecerof Fredrik 
Published: June 2016

Although pharmacological treatments can help alleviate mood symptoms in youth with paediatric bipolar disorder (PBD), residual symptoms still commonly persist. In many cases, these symptoms seriously affect the social and psychological development of children and adolescents suffering from PBD. Complementary interventions, such as psychosocial and psychoeducational treatments, can help children and their families manage mood regulation and other challenges throughout childhood and adolescence. However, most research on such interventions has focused on children, single‐family psychoeducation, and individual cognitive behavioural therapy. The present study, conducted in Sweden, used a case‐series design to explore whether child‐ and family‐focused cognitive behavioural therapy (CFF‐CBT) for PBD, adapted from children (8–12 years) to adolescents (13–18 years) and applied in a multi‐family format, could help reduce symptoms, improve psychosocial functioning, increase parents' knowledge of and skills for coping with the disorder, and improve family expressed emotion for adolescents with PBD. Furthermore, we aimed to assess whether the effects of such CFF‐CBT are maintained at a one‐year follow‐up. Seven adolescents and 11 parents in two multi‐family groups received twelve sessions of CFF‐CBT. Self‐rating questionnaires and clinical observations were used to evaluate clinically significant changes for individual cases. The results suggest that CFF‐CBT is feasible to deliver in an outpatient psychiatric setting and may be effective for developing parents' skills and knowledge for coping with PBD, increasing adolescents' psychosocial functioning, and improving family climate. The results are in line with previous findings on CFF‐CBT for children with PBD, suggesting that CFF‐CBT is a valuable adjunctive treatment for adolescents with PBD. Copyright © 2016 John Wiley & Sons, Ltd.Key Practitioner Message

Preliminary evidence indicates that CFF‐CBT (RAINBOW) is both acceptable and an important complement to pharmacological treatment for adolescents suffering from paediatric bipolar disorder (PBD).
Adolescent PBD populations show a high degree of comorbidity and individual clinical presentations that influence treatment results.
Families show a large variation in ability to participate and benefit from RAINBOW treatment. Assessing and addressing pre‐treatment environmental stressors and family climate during treatment is important for optimizing treatment effect.
Symptoms of PBD fluctuate and new episodes can occur spontaneously. It is therefore important to follow PBD symptoms over time to draw more precise conclusions on treatment effects.
When assessing treatment effects on psychiatric symptoms, social functioning, and family climate, it is important to use multiple rating sources, as ratings can vary considerably between adolescents, parents, and clinicians.
Does one model fit all? Patterns of beech mortality in natural forests of three European regions
Authors: Hülsmann Lisa , Bugmann Harald K. M. , Commarmot Brigitte , Meyer Peter , Zimmermann Stephan , Brang Peter 
Published: June 2016

AbstractLarge uncertainties characterize forest development under global climate change. Although recent studies have found widespread increased tree mortality, the patterns and processes associated with tree death remain poorly understood, thus restricting accurate mortality predictions. Yet, projections of future forest dynamics depend critically on robust mortality models, preferably based on empirical data rather than theoretical, not well‐constrained assumptions. We developed parsimonious mortality models for individual beech (Fagus sylvaticaL.) trees and evaluated their potential for incorporation in dynamic vegetation models (DVMs). We used inventory data from nearly 19,000 trees from unmanaged forests in Switzerland, Germany, and Ukraine, representing the largest dataset used to date for calibrating such models. Tree death was modelled as a function of size and growth, i.e., stem diameter (dbh) and relative basal area increment (relBAI), using generalized logistic regression accounting for unequal re‐measurement intervals. To explain the spatial and temporal variability in mortality patterns, we considered a large set of environmental and stand characteristics. Validation with independent datasets was performed to assess model generality. Our results demonstrate strong variability in beech mortality that was independent of environmental or stand characteristics. Mortality patterns in Swiss and German strict forest reserves were dominated by competition processes as indicated by J‐shaped mortality over tree size and growth. The Ukrainian primeval beech forest was additionally characterized by windthrow and a U‐shaped size–mortality function. Unlike the mortality model based on Ukrainian data, the Swiss and German models achieved good discrimination and acceptable transferability when validated against each other. We thus recommend these two models to be incorporated and examined in DVMs. Their mortality predictions respond to climate change via tree growth, which is sufficient to capture the adverse effects of water availability and competition on the mortality probability of beech under current conditions.
Urban bat communities are affected by wetland size, quality, and pollution levels
Authors: Straka Tanja Maria , Lentini Pia Eloise , Lumsden Linda Faye , Wintle Brendan Anthony , van der Ree Rodney 
Published: June 2016

AbstractWetlands support unique biota and provide important ecosystem services. These services are highly threatened due to the rate of loss and relative rarity of wetlands in most landscapes, an issue that is exacerbated in highly modified urban environments. Despite this, critical ecological knowledge is currently lacking for many wetland‐dependent taxa, such as insectivorous bats, which can persist in urban areas if their habitats are managed appropriately. Here, we use a novel paired landscape approach to investigate the role of wetlands in urban bat conservation and examine local and landscape factors driving bat species richness and activity. We acoustically monitored bat activity at 58 urban wetlands and 35 nonwetland sites (ecologically similar sites without free‐standing water) in the greater Melbourne area, southeastern Australia. We analyzed bat species richness and activity patterns using generalized linear mixed‐effects models. We found that the presence of water in urban Melbourne was an important driver of bat species richness and activity at a landscape scale. Increasing distance to bushland and increasing levels of heavy metal pollution within the waterbody also negatively influenced bat richness and individual species activity. Areas with high levels of artificial night light had reduced bat species richness, and reduced activity for all species except those adapted to urban areas, such as the White‐striped free‐tailed bat (Austronomus australis). Increased surrounding tree cover and wetland size had a positive effect on bat species richness. Our findings indicate that wetlands form critical habitats for insectivorous bats in urban environments. Large, unlit, and unpolluted wetlands flanked by high tree cover in close proximity to bushland contribute most to the richness of the bat community. Our findings clarify the role of wetlands for insectivorous bats in urban areas and will also allow for the preservation, construction, and management of wetlands that maximize conservation outcomes for urban bats and possibly other wetland‐dependent and nocturnal fauna.