bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sebaceous tumours: more than skin deep
Authors: Jockenhöfer Finja , Schimming Tobias T , Schaller Jörg , Moege Jürgen , Livingstone Elisabeth , Salva Katrin A , Zimmer Lisa , Schadendorf Dirk , Rösch Alexander 
Published: December 2017

Clinical presentationA 77-year-old man presented to our skin cancer centre with various cutaneous tumours occurring in 2006–2017. Histopathology showed a ‘hidradenocarcinoma’ on the left upper back (2006) and a sebaceous adenoma (figure 1) on the left shoulder (2011). In 2017, he developed a sebaceous carcinoma on the middle upper back, which manifested as a slowly enlarging, asymptomatic nodule. Medical history was significant for curative resection of colorectal cancer in 1988.Figure 1Clinical appearance of the sebaceous adenoma on the patient’s left shoulder in 2011.The most recent lesion was subjected to extensive immunohistochemical assessment. The neoplastic cells were positive for cytokeratin 5/6, cytokeratin 7, cluster of differentiation antigen 10, adipophilin, androgen receptor, epithelial membrane antigen, KI67 antigen, MLH1 and PMS2, but stained negative for gross cystic disease fluid protein 15, prostate-specific antigen, carbohydrate antigen 19/9, CDX2 protein, hepatocyte-specific antigen, carcinoembryonic antigen, cluster of differentiation antigen 117 and cytokeratin 19. Given the variety of histological manifestations of the patient’s skin neoplasms, further studies were performed. They revealed positive nuclear expression signals for MLH1, MSH6 and PMS2, whereas MSH2 expression was absent in almost all tumour cells (figure 2). Positron emission tomography (PET)/CT and colonoscopy did not detect any pathological findings. However, molecular genetic analysis of peripheral blood showed a heterozygous deletion of exon 7 of the MSH2 gene. Subsequently, several family members tested positive for MSH2 mutations and underwent genetic counselling.Figure 2(A–D) Histopathological images of the patient’s most recent lesion (diaminobenzidine, original magnification, ×100). The tumour cells demonstrated strong nuclear positivity for MLH1 (A) and PMS2 (B), but were essentially negative for MSH6 (C) and MSH2 (D).QuestionWhat is your diagnosis?Diagnosis: Muir-Torre syndrome (MTS).
Limits of the Universal: The Promises and Pitfalls of Postcolonial Theory and Its Critique
Authors: Anievas Alexander , Nişancıoğlu Kerem 
Published: December 2017

AbstractThis article seeks to reassess the potential merits and weaknesses of the Subaltern Studies project through the prism of Vivek Chibber’s much-publicised and controversial bookPostcolonial Theory and the Specter of Capital. By critically examining Chibber’s work, the article aims to better pinpoint exactly what is ‘right’ and ‘wrong’ with the Subaltern Studies project, while drawing out some productive points of engagement between Marxism and postcolonial theory more generally. In particular, we argue that an understanding of the origins of capitalist modernity remains a relatively unexplored omission within postcolonial thought that problematises their broader project of ‘provincialising Europe’. Against this backdrop, the article explores the affinities between Leon Trotsky’s notion of uneven and combined development and postcolonialism, demonstrating how the former can provide a theoretical solution to the problem of Eurocentrism that the Subaltern Studies project correctly identifies but inadequately conceptualises.
Local Governments’ Strategy for the Development of Social Organizations
Authors: Yan Kegao , Lin Shunhao , Ren Binbin 
Published: December 2017

AbstractIn recent years, the central government encourages local governments to innovate the system for social organization management propitious to the development of social organizations, but social organizations are double-edged, which can both alleviate the social management pressure of local governments and challenge their authority. Therefore, local governments have to implement the strategy of differential control for managing social organizations. The theory of differential control is an important paradigm for explaining the government-society relationship in China, as it provides a theoretical framework for understanding local governments’ behavioral logic of developing social organizations, but local governments’ specific application and change of the strategy about differential control still need to be further explored. Based on the above observation, by collecting the panel data of 312 prefecture-level cities of China in 2008-2014, we have discovered that local governments, on the whole, have adopted the development strategy of “developing quantity and restraining capability.” They give priority to developing social organizations promoting economic development and social service, but implement strict control over environmental, legal, and international foreign-related organizations affecting the realization of economic goals or political stability. With a more developed economy and better fiscal revenues, a more lenient environment is given to social organizations by local governments, and social organizations are more developed. But the control over environmental social organizations does not change with the changes of economic development or fiscal revenues. This study not only expands the theory of differential control and provides a new understanding of the relations between government and social organizations, but also reveals local governments’ behavioral logic of developing social organizations, which also provides a new perspective for understanding local governments’ behaviors in developing social organizations.
The Background, Dilemma and Path for Buddhist Charities to Engage in Social Protection of the Children in Plight
Authors: Chen Jing , Lan Qing 
Published: December 2017

Abstract
The state, the market, the family and social organizations play exchangeable and mutually complimentary roles in provision of social welfare to children. The Buddhist charities play an increasingly important role in offering social protection to the children in plight, from ensuring the basic livelihood for the children and meeting the children’s need for development to guaranteeing the children social security and encouraging and facilitating the children’s social engagement. Due to the constraints of charity systems, the stereotypical impression about religions and the defects in the internal governance structure of the Buddhist charities, such charities face a host of problems in joining in the endeavor to protect the children in plight, such as the failure to get registered in a timely and legal manner, their marginal existence leading to inadequate protection to the children in plight and the distortion of their organization culture. This article, based on a case study of Hongde Homeland offering aid to the orphans in poverty-stricken mountainous areas, explores the background and strategy for the Buddhist charities to protect the children in plight and makes policy proposals on the appropriate ways to offer the children in plight religious welfare as a part of social protection.
Ochre Resources, Behavioural Complexity and Regional Patterns in the Howiesons Poort
Authors: Dayet Bouillot Laure , Wurz Sarah , Daniel Floréal 
Published: December 2017

AbstractThe widespread use of ochre during Oxygen Isotope Stage 5 and 4 in South Africa has often been interpreted as reflecting complex behaviours amongst modern human populations. The Howiesons Poort is one of the most documented techno-complexes identified within this timeframe. It is associated with an intensification of a combination of innovative technical and symbolic behaviours. Despite the notable focus on ochre use, detailed analyses of Howiesons Poort assemblages in this respect are rare. New data on ochre exploitation from the Howiesons Poort of Klasies River main site are presented in this paper. We used non-destructive microscopic, colorimetric and chemical analyses (sem-eds,xrd) in order to describe the raw materials and the transformation of a selected sample from the Singer and Wymer ochre collection. This sample is composed of red and yellow ferruginous rocks (shale, ferricrete, siltstone and sandstone), along with whitish lumps (calcium phosphates). These lumps may have an anthropogenic origin and may be considered as pigments. Some of the red ochre pieces were probably deliberately heated. Our results enhance the impression of complexity emerging from the technical processes mastered by Howiesons Poort populations. Comparison with other Howiesons Poort ochre assemblages allows a discussion of regional variability and ‘connections’ between the sites. The scale and organization of social interactions in the Howiesons Poort are questioned.
Contrasting Polarimetric Observations of Stratiform Riming and Nonriming Events
Authors: Vogel Jonathan M. , Fabry Frédéric 
Published: December 2017

AbstractThis study investigates the how riming in stratiform precipitation impacts polarimetric signatures. Using a vertically pointing Doppler X-band radar, cases can be separated into one of three groups: unrimed to lightly rimed, riming with no bimodal spectra and fall speeds greater than 2.0 m s−1, and riming with bimodal velocity spectra. By averaging polarimetric variables over a 20° by 10-km box near the X-band radar, different signatures were documented for each of the three groups. These polarimetric signatures were then compared with a simplified T-matrix scattering model. Differential reflectivity ZDR was the one polarimetric variable to consistently vary across all three groups. Unrimed to lightly rimed cases had profiles of polarimetric signatures similar to numerous previous studies. Riming cases without detectable bimodal spectra had ZDR values on the order of 0.2 dB lower than unrimed to lightly rimed cases, while cases with bimodal spectra had ZDR values about 0.2–0.4 dB higher than unrimed to lightly rimed cases. Both signatures were reproduced using populations of aggregates, dendrites, and needles in the T-matrix scattering model. While these signatures show the potential to identify riming, they are not enough larger than measurement biases and case-to-case variability to be confidently used without confirmation from other data sources, such as a vertically pointing radar.
Evolutionary basis of HLA-DPB1 alleles affects acute GVHD in unrelated donor stem cell transplantation
Authors: Morishima Satoko , Shiina Takashi , Suzuki Shingo , Ogawa Seishi , Sato-Otsubo Aiko , Kashiwase Koichi , Azuma Fumihiro , Yabe Toshio , Satake Masahiro , Kato Shunichi , Kodera Yoshihisa , Sasazuki Takehiko , Morishima Yasuo 
Published: December 2017

Key PointsHLA-DPB1 alleles diverged into 2 major groups according to highly conserved DNA sequences Ex3-3′UTR. Two evolutionarily different HLA-DPB1 gene regions complementarily affect aGVHD in HLA-DPB1 mismatch UR-HCT.
Incidence and predictors of failed second-generation endometrial ablation
Authors: Klebanoff Jordan , Makai Gretchen E. , Patel Nima R. , Hoffman Matthew K. 
Published: December 2017

Abstract
Background
The need for any treatment following an endometrial ablation is frequently cited as “failed therapy,” with the two most common secondary interventions being repeat ablation and hysterectomy. Since second-generation devices have become standard of care, no large cohort study has assessed treatment outcomes with regard to only these newer devices. We sought to determine the incidence and predictors of failed second-generation endometrial ablation, defined as the need for surgical re-intervention.
We performed a retrospective cohort study at a single academic-affiliated community hospital. Subjects included women undergoing second-generation endometrial ablation for benign indications between October 2003 and March 2016. Second-generation devices utilized during the study period included the radiofrequency ablation device (RFA), hydrothermal ablation device (HTA), and the uterine balloon ablation system (UBA).

Results
Five thousand nine hundred thirty-six women underwent endometrial ablation at a single institution (3757 RFA (63.3%), 1848 HTA (31.1%), and 331 UBA (5.6%)). The primary outcome assessed was surgical re-intervention, defined as hysterectomy or repeat endometrial ablation. Of the total 927 (15.6%) women who required re-intervention, 822 (13.9%) underwent hysterectomy and 105 (1.8%) underwent repeat endometrial ablation. Women who underwent re-intervention were younger (41.6 versus 42.9 years, p < .001), were more often African-American (21.8% versus 16.2%, p < .001), and were more likely to have had a primary radiofrequency ablation procedure (hazard ratio 1.37; 95%CI 1.01 to 1.86). Older age was associated with decreased risk for treatment failure with women older than 45 years of age having the lowest risk for failure (p < .001). Age between 35 and 40 years conferred the highest risk of treatment failure (HR 1.59, 95% CI 1.32–1.92). Indications for re-intervention following ablation included menorrhagia (81.8%), abnormal uterine bleeding (27.8%), polyps/fibroids (18.7%), and pain (9.5%).

Conclusion
Surgical re-intervention was required in 15.6% of women who underwent second-generation endometrial ablation. Age, ethnicity, and radiofrequency ablation were significant risk factors for failed endometrial ablation, and menorrhagia was the leading indication for re-intervention.
Probabilistic b-metric spaces and nonlinear contractions
Authors: Mbarki Abderrahim , Oubrahim Rachid 
Published: December 2017

AbstractThis work is for giving the probabilistic aspect to the known b-metric spaces (Czerwik in Atti Semin. Mat. Fis. Univ. Modena 46(2):263-276, 1998), which leads to studying the fixed point property for nonlinear contractions in this new class of spaces.
Draft genome sequence of the type strain of the sulfur-oxidizing acidophile, Acidithiobacillus albertensis (DSM 14366)
Authors: Castro Matías , Moya-Beltrán Ana , Covarrubias Paulo C. , Gonzalez Mónica , Cardenas Juan Pablo , Issotta Francisco , Nuñez Harold , Acuña Lillian G. , Encina Gonzalo , Holmes David S. , Johnson D. Barrie , Quatrini Raquel 
Published: December 2017

AbstractAcidithiobacillus albertensis is an extremely acidophilic, mesophilic, obligatory autotrophic sulfur-oxidizer, with potential importance in the bioleaching of sulfidic metal ores, first described in the 1980s. Here we present the draft genome sequence of Acidithiobacillus albertensis DSM 14366T, thereby both filling a long-standing gap in the genomics of the acidithiobacilli, and providing further insight into the understanding of the biology of the non iron-oxidizing members of the Acidithiobacillus genus. The assembled genome is 3,1 Mb, and contains 47 tRNAs, tmRNA gene and 2 rRNA operons, along with 3149 protein-coding predicted genes. The Whole Genome Shotgun project was deposited in DDBJ/EMBL/GenBank under the accession MOAD00000000.
Draft genome sequence of Pseudomonas extremaustralis strain USBA-GBX 515 isolated from Superparamo soil samples in Colombian Andes
Authors: López Gina , Diaz-Cárdenas Carolina , Shapiro Nicole , Woyke Tanja , Kyrpides Nikos C. , David Alzate J. , González Laura N. , Restrepo Silvia , Baena Sandra 
Published: December 2017

AbstractHere we present the physiological features of Pseudomonas extremaustralis strain USBA-GBX-515 (CMPUJU 515), isolated from soils in Superparamo ecosystems, > 4000 m.a.s.l, in the northern Andes of South America, as well as the thorough analysis of the draft genome. Strain USBA-GBX-515 is a Gram-negative rod shaped bacterium of 1.0–3.0 μm × 0.5–1 μm, motile and unable to form spores, it grows aerobically and cells show one single flagellum. Several genetic indices, the phylogenetic analysis of the 16S rRNA gene sequence and the phenotypic characterization confirmed that USBA-GBX-515 is a member of Pseudomonas genus and, the similarity of the 16S rDNA sequence was 100% with P. extremaustralis strain CT14–3T. The draft genome of P. extremaustralis strain USBA-GBX-515 consisted of 6,143,638 Mb with a G + C content of 60.9 mol%. A total of 5665 genes were predicted and of those, 5544 were protein coding genes and 121 were RNA genes. The distribution of genes into COG functional categories showed that most genes were classified in the category of amino acid transport and metabolism (10.5%) followed by transcription (8.4%) and signal transduction mechanisms (7.3%). We performed experimental analyses of the lipolytic activity and results showed activity mainly on short chain fatty acids. The genome analysis demonstrated the existence of two genes, lip515A and est515A, related to a triacylglycerol lipase and carboxylesterase, respectively. Ammonification genes were also observed, mainly nitrate reductase genes. Genes related with synthesis of poly-hydroxyalkanoates (PHAs), especially poly-hydroxybutyrates (PHBs), were detected. The phaABC and phbABC operons also appeared complete in the genome. P. extremaustralis strain USBA-GBX-515 conserves the same gene organization of the type strain CT14–3T. We also thoroughly analyzed the potential for production of secondary metabolites finding close to 400 genes in 32 biosynthetic gene clusters involved in their production.
FORMAÇÃO CONTINUADA EM UMA ESCOLA DE TEMPO INTEGRAL: NOTAS SOBRE UM ESTUDO DE CASO
Authors: Bernado Elisangela Da Silva , Vasconcellos Katia Regina Teixeira 
Published: December 2017

O artigo oportuniza refletir sobre a formação dos professores que atuam em uma escola, que atende aos cinco primeiros anos do ensino fundamental em tempo integral, e se essa formação é suficiente para proporcionar aos docentes uma formação mais completa com a participação desses profissionais em cursos, palestras e encontros formativos e formações continuadas em serviço, assim, traremos alguns apontamentos de como esses profissionais percebem mudanças em sua prática pedagógica. Como questão problema, destacamos: como a formação continuada oferecida pela rede municipal de educação altera (ou não) a prática do professor? Participaram do estudo qualitativo, em 2015/2016, dezenove professores de uma escola municipal, localizada no município de Niterói, Rio de Janeiro. Com relação aos instrumentos de pesquisa para o apanhado das informações, utilizamos questionários com questões fechadas e abertas e entrevistas semiestruturadas, além da observação dos espaços (escola e Fundação Municipal de Educação) para tentar fazer links entre a política e a prática de formação para os professores, propondo uma reflexão teórica e priorizando uma análise qualitativa. Em quase sua totalidade, os participantes relataram considerar sua formação inicial insuficiente para exercerem sua função. Percebemos aqui a necessidade de trocas e espaços formativos que fortaleçam os professores no sentido de valorizarem seus saberes desenvolvidos através de suas práticas diárias.
Abstract Nonconforming Error Estimates and Application to Boundary Penalty Methods for Diffusion Equations and Time-Harmonic Maxwell’s Equations
Authors: Ern Alexandre , Guermond Jean-Luc 
Published: December 2017

Abstract
We devise a novel framework for the error analysis of finite element
approximations to low-regularity solutions in nonconforming settings
where the discrete trial and test spaces are not subspaces of their
exact counterparts. The key is to use face-to-cell extension
operators so as to give a weak meaning to the normal or tangential
trace on each mesh face individually for vector fields with minimal
regularity and then to prove the consistency of this new formulation
by means of some recently-derived mollification operators that
commute with the usual derivative operators. We illustrate the
technique on Nitsche’s boundary penalty method applied to a scalar
diffusion equation and to the time-harmonic Maxwell’s equations. In
both cases, the error estimates are robust in the case of
heterogeneous material properties. We also revisit the error
analysis framework proposed by Gudi where a trimming operator is
introduced to map discrete test functions into conforming test
functions. This technique also gives error estimates for minimal
regularity solutions, but the constants depend on the material
properties through contrast factors.
Depois do fim do platonismo fenomenológico: Hermann Lübbe e a descrição da aceleração civilizacional moderna
Authors: Da Mata Sergio 
Published: December 2017

O objetivo do artigo é oferecer uma visão geral da obra filosófica de Hermann Lübbe. Para tanto, deu-se ênfase a dois de seus principais campos de investigação: história da filosofia e fenomenologia da experiência do tempo nas sociedades modernas. A exposição está organizada em quatro momentos: (1) contextualização intelectual, (2) as críticas de Habermas às suas posições, (3) o pluralismo metodológico de Lübbe e (4) sua descrição das consequências sociais e culturais da aceleração civilizacional moderna, bem como as possibilidades que se abrem para tal abordagem na análise das “jornadas de junho” de 2013.
Estratégias autorregulatórias para o controle do desempenho em estudantes universitários: mudanças após processo reflexivo
Authors: Gomes Rodrigues Miranda Célia Artemisa , Rodrigues Nonticuri Amélia , Bragagnolo Frison Lourdes Maria 
Published: December 2017

Este artigo objetiva apresentar as estratégias autorregulatórias que os estudantes universitários sinalizaram que efetivamente utilizam (Real) para o controle do desempenho, comparando com aquelas que consideram mais relevantes para melhorar sua aprendizagem (Ideal). Além disso, pontuamos as percepções em relação à escolha destas estratégias. Participaram 19 estudantes brasileiros, que marcaram no Questionário de Estratégias de Autorregulação do Controle do Desempenho – (QEACD Real-Ideal), a estratégia da Gestão da atenção (79%). As mudanças mais expressivas se deram nas estratégias das dimensões Pedir ajuda e Gestão emocional/da ansiedade, que após processo reflexivo gerado pela pesquisa, decidiram adotar, conforme relatos da entrevista final.
Evaluación de las actitudes hacia la diversidad sexual de adolescentes del ámbito semi-rural gallego
Authors: Rodríguez-Castro Yolanda , Alonso-Ruido Patricia 
Published: December 2017

El objetivo de este estudio consiste en analizar las actitudes hacia la diversidad sexual de los y las adolescentes del ámbito semi-rural. Para ello contamos con una muestra de 150 adolescentes del 2º ciclo de la E.S.O, con una media de edad de 15.9. Los resultados muestran que los chicos son más homófobos que las chicas. Destacar que los chicos tienen actitudes más positivas hacia el lesbianismo que hacia la homosexualidad. Los/as chicos/as más sexistas hostiles son los que tienen actitudes más negativas hacia el lesbianismo/homosexualidad. También los/as adolescentes del ámbito semi-rural presentan mayores niveles de homofobia y de sexismo.
Acoso escolar en primaria tras la formación en técnicas de mediación: UPF4
Authors: Rolán Katia , Martínez-Valladares Macarena , Parada Vanesa , Abilleira Andrea , Fariña Francisca 
Published: December 2017

El acoso escolar constituye un motivo de preocupación en el ámbito educativo y social. La mediación entre iguales se presenta como una herramienta para abordar los problemas de convivencia y violencia, a través del diálogo y el uso del lenguaje amigable. Este estudio analiza si en alumnos de 5º de Educación Primaria la formación en técnicas de mediación incide en la percepción de haber sufrido acoso escolar. Los participantes fueron 30 alumnos, de dos aulas diferentes. La formación se realizó aplicando la Unidad didáctica Reformulando. Para medir la percepción de acoso se utilizó la Escala UPF-4 de Acoso Escolar.