bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of polyphenylene sulfide containing amino unit on thermal and mechanical properties of polyphenylene sulfide/glass fiber composites
Authors: Ren Hao‐Hao , Xu Dong‐Xia , Yu Ting , Yang Jia‐Chao , Zhang Gang , Wang Xiao‐Jun , Yang Jie 
Published: October 2017

ABSTRACTThree kinds of high‐molecular‐weight compatibilizers [copoly(1,4‐phenylene sulfide)‐poly(2,5‐phenylene sulfide amine)] (PPS‐NH2) containing different proportions of amino units in the side chain) were synthesized by the reaction of dihalogenated monomer and sodium sulfide via nucleophilic substitution polymerization under high pressure. The intrinsic viscosity of the obtained copolymers was 0.354–0.489 dL/g and they were found to have good thermal performance with melting point (Tm) of 271.3–281.0 °C and initial degradation temperature (Td) of 490.0–495.7 °C. There was an excellent physical compatibility between PPS‐NH2 and the pure industrial PPS. The results of dynamic mechanical analysis and macro‐ and micromechanical test showed that the selective compatibilizer PPS‐NH2 (1.0) (1.0% mol aminated ratio) can improve the mechanical and interfacial properties of polyphenylene sulfide/glass fiber (PPS/GF) composite. The macro‐optimal tensile strength, Young's modulus, bending strength, and notched impact strength of 5%PPS‐NH2 (1.0)/PPS/GF composite raised up to 141 MPa, 1.98 GPa, 203 MPa, and 6.15 kJ/m2, which increased 12.8%, 9.4%, 4.1%, and 13.8%, respectively, comparing with the pure PPS/GF composite (125 MPa, 1.81 GPa, 195 MPa, and 5.40 kJ/m2, respectively). © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45804.
Experimental and MD simulation study on the physical and mechanical properties of organically modified montmorillonite clay and compatibilized linear low density polyethylene nanocomposites
Authors: Yildirim Erol , Yurtsever Mine , Eriman Bülent , Uyanik Nurseli 
Published: October 2017

ABSTRACTUnderstanding the interfacial interactions plays a key role in controlling mechanical and physical properties of polymer/clay nanocomposites (PCNs). In this work, the surface interactions between constituents of experimentally prepared PCNs which are the pristine linear low density polyethylene (PE) chains, PE compatibilizers, montmorillonite clay surface layer, and surfactants were studied quantitatively by employing molecular dynamics simulation technique. The interaction energy between the polymer and the clay was found to be inversely proportional with the volume of the surfactant which decreases the electrostatic interactions between the compatibilizer and the hydrophilic clay surface. However, the van der Waals (vdW) interactions between alkyl tails of surfactants and the PE chains increase with the tail length of the surfactants. The most attractive interaction was between the surfactant's head group and the clay surface. We showed that there existed fine balance between the electrostatic and vdW type forces on the stability and the enhanced properties of the PE–organoclay nanocomposites. Calculated interaction energies were then correlated to the experimentally measured mechanical properties. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45817.
A biaxial stretched β‐isotactic polypropylene microporous membrane for lithium‐ion batteries
Authors: Yang Shuting , Gu Jifeng , Yin Yanhong 
Published: October 2017

ABSTRACTIn this article, microporous polypropylene (PP) membranes were produced with TMB‐5 as β‐crystal nucleating agent by biaxial stretching. Influences of different concentration of TMB‐5 were studied using differential scanning calorimetry and X‐ray diffraction. It was found that the highest crystallinity was reached when the nucleating agent content was 0.5 wt %. The effect of stretching temperature and stretching ratio on pore size distribution and porosity of the membranes were investigated by scanning electron microscopy and mercury porosimeter, respectively. And physical properties, such as tensile strength, permeability, and puncture resistance of the microporous membrane prepared at the optimized conditions, were evaluated. Compared with commercial PP separator membrane, the as‐prepared microporous membrane shows similar uniform pore size distribution and exhibits slightly higher porosity and ionic conductivities. When used as lithium‐ion separator, the experimental film shows more stable cycling performance than the commercial one. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45825.
Using Digital Tags With Integrated Video and Inertial Sensors to Study Moving Morphology and Associated Function in Large Aquatic Vertebrates
Authors: Goldbogen J.A. , Cade D.E. , Boersma A.T. , Calambokidis J. , Kahane‐Rapport S.R. , Segre P.S. , Stimpert A.K. , Friedlaender A.S. 
Published: October 2017

ABSTRACTThe anatomy of large cetaceans has been well documented, mostly through dissection of dead specimens. However, the difficulty of studying the world's largest animals in their natural environment means the functions of anatomical structures must be inferred. Recently, non‐invasive tracking devices have been developed that measure body position and orientation, thereby enabling the detailed reconstruction of underwater trajectories. The addition of cameras to the whale‐borne tags allows the sensor data to be matched with real‐time observations of how whales use their morphological structures, such as flukes, flippers, feeding apparatuses, and blowholes for the physiological functions of locomotion, feeding, and breathing. Here, we describe a new tag design with integrated video and inertial sensors and how it can be used to provide insights to the function of whale anatomy. This technology has the potential to facilitate a wide range of discoveries and comparative studies, but many challenges remain to increase the resolution and applicability of the data. Anat Rec, 300:1935–1941, 2017. © 2017 Wiley Periodicals, Inc.
The Quest of Excited‐State Intramolecular Proton Transfer via Eight‐Membered Ring π‐Conjugated Hydrogen Bonding System
Authors: Meng Fan‐Yi , Hsu Yen‐Hao , Zhang Zhiyun , Wu Pei‐Jhen , Chen Yi‐Ting , Chen Yi‐An , Chen Chi‐Lin , Chao Chi‐Min , Liu Kuan‐Miao , Chou Pi‐Tai 
Published: October 2017

AbstractSearching for eight‐membered ring π‐conjugated hydrogen bonding (8‐MR H‐bonding) systems with excited‐state intramolecular proton transfer (ESIPT) property is seminal and synthetically challenging. In this work, a series of π‐conjugated molecules (8‐HB‐1, 8‐HB‐L1 and 8‐HB‐2) potentially possessing 8‐MR H‐bonding are strategically designed, synthesized and characterized. The configurations of these three potential molecules are checked by their X‐ray structures, among which 8‐HB‐L1 (a structurally locked 8‐HB‐1 core chromophore) is proved to be an 8‐MR H‐bonding system, whereas 8‐HB‐1 and 8‐HB‐2 are too sterically hindered to form the 8‐MR intramolecular H‐bond. The ESIPT property of 8‐HB‐L1 is confirmed by the dual fluorescence consisting of normal and proton‐transfer tautomer emissions. The insight into the ESIPT process of 8‐HB‐L1 is provided by femtosecond fluorescence upconversion measurements together with computational simulation. The results demonstrate for the first time a successful synthetic route to attain the 8‐MR H‐bonding molecule 8‐HB‐L1 with ESIPT property.
Cyclization Reactions of Aryl Propargyl Acetates with Tethered Epoxide Induced by Ruthenium Complex
Authors: Feng Yi‐Jhen , Chen Yi‐Hsin , Huang Shou‐Ling , Liu Yi‐Hung , Lin Ying‐Chih 
Published: October 2017

AbstractReactions of the ruthenium complex [Ru]Cl ([Ru]=Cp(PPh3)2Ru; Cp=η5‐C5H5) with several aryl propargyl acetates, each with an ortho‐substituted chain of various length containing an epoxide on the aromatic ring and with or without methyl substitutents on the epoxide ring, bring about novel cyclizations. The cyclization reactions of HC≡CCH(OAc)(C6H4)CH2(RC2H2O) (R=H, 6 a; R=CH3, 6 b, where RC2H2O is an epoxide ring) in MeOH give the vinylidene complexes 5 a–b, respectively, each with the Cβ integrated into a tetrahydro‐5H‐benzo[7]annulen‐6‐ol ring. A C−C bond formation takes place between the propargyl acetate and the less substituted carbon of the epoxide ring. Further cyclizations of 5 a–b induced by HBF4 give the corresponding vinylidene complexes 8 a–b each with a new 8‐oxabicyclo‐[3.2.1]octane ring by removal of a methanol molecule in high yield. For similar aryl propargyl acetates with a shorter epoxide chain, the cyclization gives a mixture of a vinylidene complex with a tetrahydronaphthalen‐1‐ol ring and a carbene complex with a tricyclic indeno‐furan ring. For the cyclization of 18, with a longer epoxide chain, opening of the epoxide is required to afford the vicinal bromohydrin 22, then tandem cyclization occurs in one pot. Products are characterized by spectroscopic methods as well as by XRD analysis.
Synthesis of MOF‐525 Derived Nanoporous Carbons with Different Particle Sizes for Supercapacitor Application
Authors: Chang Ting‐Hsiang , Young Christine , Lee Min‐Han , Salunkhe Rahul R. , Alshehri Saad M. , Ahamad Tansir , Islam Md. Tofazzal , Wu Kevin C.‐W. , Hossain Md. Shahriar A. , Yamauchi Yusuke , Ho Kuo‐Chuan 
Published: October 2017

AbstractNanoporous carbon (NC) materials have attracted great research interest for supercapacitor applications, because of their excellent electrochemical and mechanical stability, good electrical conductivity, and high surface area. Although there are many reports on metal–organic framework (MOF)‐derived carbon materials, previous synthetic studies have been hindered by imperfect control of particle sizes and shapes. Here, we show precise control of the particle sizes of MOF‐525 from 100 nm to 750 nm. After conversion of MOF‐525 to NC, the effects of variation of the particle size on the electrochemical performance have been carefully investigated. The results demonstrate that our NC is a potential candidate for practical supercapacitor applications.
The BMP antagonist Noggin is produced by osteoblasts in response to the presence of prostate cancer cells
Authors: AlShaibi Huda F. , Ahmed Farid , Buckle Clive , Fowles Ann C.M. , Awlia Jalaluddin , Cecchini Marco G. , Eaton Colby L. 
Published: October 2017

AbstractBone metastasis is a key event responsible for morbidity in prostate cancer patients. Interactions between prostate cancer cells and the bone microenvironment facilitate survival of tumor cells and alter bone turnover, a process that is thought to enhance the growth of metastases in this site. This study aimed to test the hypothesis that the presence of tumors cells increases transforming growth factor beta (TGF‐β) signaling in bone and that this regulates the proliferation and differentiation of osteoblastic lineage cells in metastatic sites. Initial studies showed that factors produced by prostate cancer cells increased the proliferation of osteoblastic cells and suppressed the early phase of their differentiation. We subsequently showed that interactions between prostate cancer and osteoblastic cells affected the expression of TGF‐β superfamily genes in the latter. Noggin was expressed and secreted by prostate cancer cells but expressed at very low levels by osteoblastic cells when these cells were grown alone. This pattern changed when osteoblasic cells were treated with conditioned medium derived from prostate cancer cells or were cocultured with the latter, with strong induction of Noggin being demonstrated. Immunohistochemical examination of prostate cancer xenografts showed strong Noggin protein staining on endosteal bone surfaces and in bone lining cells in close proximity to tumor foci. These studies support previous work that suggest Noggin is an important suppressor of the differentiation of osteoblast lineage cells in bone metastases. Importantly, we have now also shown that this protein can be induced in bone cells themselves by factors derived from prostate cancer cells.
Organotypic brain explant culture as a drug evaluation system for malignant brain tumors
Authors: Minami Noriaki , Maeda Yusuke , Shibao Shunsuke , Arima Yoshimi , Ohka Fumiharu , Kondo Yutaka , Maruyama Koji , Kusuhara Masatoshi , Sasayama Takashi , Kohmura Eiji , Saya Hideyuki , Sampetrean Oltea 
Published: October 2017

AbstractTherapeutic options for malignant brain tumors are limited, with new drugs being continuously evaluated. Organotypic brain slice culture has been adopted for neuroscience studies as a system that preserves brain architecture, cellular function, and the vascular network. However, the suitability of brain explants for anticancer drug evaluation has been unclear. We here adopted a mouse model of malignant glioma based on expression of H‐RasV12 in Ink4a/Arf−/− neural stem/progenitor cells to establish tumor‐bearing brain explants from adult mice. We treated the slices with cisplatin, temozolomide, paclitaxel, or tranilast and investigated the minimal assays required to assess drug effects. Serial fluorescence‐based tumor imaging was sufficient for evaluation of cisplatin, a drug with a pronounced cytotoxic action, whereas immunostaining of cleaved caspase 3 (a marker of apoptosis) and of Ki67 (a marker of cell proliferation) was necessary for the assessment of temozolomide action and immunostaining for phosphorylated histone H3 (a marker of mitosis) allowed visualization of paclitaxel‐specific effects. Staining for cleaved caspase 3 was also informative in the assessment of drug toxicity for normal brain tissue. Incubation of explants with fluorescently labeled antibodies to CD31 allowed real‐time imaging of the microvascular network and complemented time‐lapse imaging of tumor cell invasion into surrounding tissue. Our results suggest that a combination of fluorescence imaging and immunohistological staining allows a unified assessment of the effects of various classes of drug on the survival, proliferation, and invasion of glioma cells, and that organotypic brain slice culture is therefore a useful tool for evaluation of antiglioma drugs.
Incidence, risk factors, and outcomes of central venous catheter‐related thromboembolism in breast cancer patients: the CAVECCAS study
Authors: Debourdeau Philippe , Espié Marc , Chevret Sylvie , Gligorov Joseph , Elias Antoine , Dupré Pierre François , Desseaux Kristell , Kalidi Issa , Villiers Stephane , Giachetti Sylvie , Frere Corinne , Farge Dominique 
Published: October 2017

AbstractPrevious epidemiologic studies investigating central venous catheter (CVC)‐related venous thromboembolism (CRT) were conducted in heterogenous cancer populations and data in breast cancer (BC) remain limited. To investigate the Doppler ultrasound (DUS)‐CRT incidence, risk factors and outcomes in BC, we designed a prospective, multicenter cohort of nonmetastatic invasive BC patients undergoing insertion of a CVC for chemotherapy. All patients underwent double‐blind DUS before, 7, 30, and 90 days after CVC insertion and a 6 months clinical follow‐up. Symptomatic DUS‐CRT were treated by anticoagulants. D‐Dimers, thrombin generation, and platelet‐derived microparticles were measured before and 2 days after CVC placement. In DUS‐CRT patients, a nested case–control study analyzed the role of thrombophilia. Among 524 patients, the DUS‐CRT (14 symptomatic, 46 asymptomatic) cumulative probability was 9.6% at 3 months and 11.5% at 6 months (overall incidence rate: 2.18/100 patient‐months). Ten/14 symptomatic DUS‐CRT were detected on double‐blind DUS before the clinical symptoms, and 3/14 had a simultaneous pulmonary embolism. No clinical thrombotic event subsequently occurred in untreated asymptomatic DUS‐CRT. Age >50 years (OR, 1.80; 95% CI, 1.01–3.22), BMI >30 kg/m² (OR, 2.64; 95% CI, 1.46–4.76) and comorbidities (OR, 2.05; 95% CI, 1.18–3.56) were associated with DUS‐CRT. No biomarkers was found to predict DUS‐CRT. In multivariate analysis, BMI >30 kg/m² (OR, 2.66; 95%CI, 1.46–4.84) and lobular carcinoma histology (OR, 2.56; 95%CI, 1.32–4.96) remained the only significant DUS‐CRT risk factors. Thrombophilia did not account for DUS‐CRT. Only clinical parameters identified high risk DUS‐CRT patients who may be considered for thromboprophylaxis.
Social determinants of stage IV anal cancer and the impact of pelvic radiotherapy in the metastatic setting
Authors: Repka Michael C. , Aghdam Nima , Karlin Andrew W. , Unger Keith R. 
Published: October 2017

AbstractAnal cancer is a relatively rare malignancy, and a minority of patients present with metastatic disease in the United States. The National Cancer Database (NCDB) was used to identify factors associated with metastatic disease at presentation and evaluate the role of pelvic radiotherapy in these patients. The NCDB was queried for patients with squamous cell cancer of the anus diagnosed between 2004 and 2013. Patients were stratified by clinical stage at diagnosis, and a binary logistic regression model was created to identify factors associated with metastatic disease at diagnosis. A secondary metastatic cohort was generated and a multivariable Cox proportional hazards model was created to identify factors associated with improved survival. To validate findings, propensity‐score matching was performed to generate a 1:1 paired dataset stratified by receipt of pelvic radiotherapy. The primary analysis cohort consisted of 28,500 patients. Facility location, male gender, and lack of insurance were confirmed as independent risk factors for metastatic disease. The metastatic cohort consisted of 1264 patients. Multivariable analysis confirmed female sex, possession of a private or Medicare insurance plan, pelvic radiotherapy, and chemotherapy as independent predictors of improved survival. A propensity‐score matched cohort of 730 patients was generated. The median survival was 17.6 months in patients who received radiotherapy versus 14.5 months in those who did not (P < 0.01). In this cohort, male gender and lack of insurance were associated with metastatic disease at presentation. Furthermore, a significant benefit was associated with the use of pelvic radiotherapy. Future prospective research is warranted to confirm these findings.
Initial results of a first‐in‐human study on the PlasmaWire™ System, a new radiofrequency wire for recanalization of chronic total occlusions
Authors: Kanno Daitaro , Tsuchikane Etsuo , Nasu Kenya , Katoh Osamu , Kashima Yoshifumi , Kaneko Umihiko , Fujita Tsutomu , Suzuki Yoriyasu , Suzuki Takahiko 
Published: October 2017

AbstractObjectivesTo examine the safety, efficacy, and efficiency of the PlasmaWireTM System to recanalize coronary chronic total occlusions (CTO) using controlled ablation inside the CTO.BackgroundThe PlasmaWireTM System is a new bipolar radiofrequency (RF) wire system utilizing plasma‐mediated ablation to facilitate wire crossing in CTOs. Two independent PlasmaWireTM wires are used in tandem for channel creation by applying RF energy between the tips so as to localize the ablation.MethodsProspective, nonrandomized, single‐arm, multicenter study in seven patients with CTOs indicated for percutaneous coronary intervention (PCI).ResultsIn this study, both wires were antegradely delivered to the distal end of CTO for antegrade re‐entry in two cases and bidirectionally (antegrade and retrograde) delivered to the CTO for retrograde re‐entry in five cases. In all cases, channel creation was achieved within a few seconds and was confirmed on angiogram or intravascular ultrasound (IVUS) and CTO recanalization was successfully achieved without any major adverse cardiac and cerebrovascular events (MACCE) or other minor complications. The clinical follow‐up showed no clinical event at 1 month.ConclusionsThe PlasmaWireTM System was shown to be safe and effective in obtaining CTO recanalization through a re‐entry channel utilizing plasma‐mediated ablation while reducing procedure time. The PlasmaWire™ System is a new bi‐polar RF wire system utilizing plasma‐mediated ablation for channel creation to facilitate CTO recanalization. This first‐in‐human study in which seven patients were enrolled was conducted to demonstrate the safety, efficacy, and efficiency of this system for CTO recanalization. Channels through the CTOs were successfully created within a few seconds by applying RF energy between the tips of two independent PlasmaWireTM wires and recanalization was achieved in all cases without any complication. The PlasmaWireTM System may safely facilitate CTO recanalization with less vessel injury and improve initial results of CTO PCI while reducing procedure time.
Safety and feasibility of same‐day early discharge after endovascular revascularization of lower extremities in elderly. SENIOR‐ER registry
Authors: Janas Adam , Milewski Krzysztof , Buszman Piotr P. , Janas Ksenia , Blachut Aleksandra , Pruski Maciej , Wiernek Szymon , Zurakowski Aleksander , Buszman Pawel E. , Kiesz Stefan R. 
Published: October 2017

AbstractObjectiveThe aim of the study was to assess safety and feasibility of one‐day early discharge (ODD) after endovascular revascularization (ER) of lower extremities in elderly.BackgroundSafety and feasibility of ODD after ER have never been investigated in the elderly, despite the PAD rate has been rising in well‐developed countries as their populations are getting older.MethodsThe consecutive data of 477 patients after ER who were intended to ODD were reviewed. The ER procedure (balloon angioplasty, atherectomy, stenting) was performed due to significant, angiographically confirmed arterial stenosis with at least Rutheford III claudication. The population was divided into two groups: ≥70 years old (y. o.) in which were 235 patients and 220 patients <70 y. o., the younger control cohort. The follow‐up was performed 24 hr after (24FU) the procedure and 30 days (30FU) after discharge.ResultsThere were no differences between the groups in the ratio of same‐day discharge (99% vs 99.5%, P = 0.6) and the mean time to ambulation was 287.4 ± 43.4 min versus 285.8 ± 45.7 min (P = 0.603). The ODD was not applied in 2 patients ≥70 y. o. due to two pseudoaneurysms requiring surgical repairs and in one from the control group due to retroperitoneal bleeding. There was no MACE or creatinine increase at 24 hr in both groups. At 30 days, there was no incidence of MACE in the ≥70 y. o. group while 3 MACE occurred in the control. The ratio of access site complications was comparable between the groups.ConclusionThe study allows for a hypothesis that the advantages of ODD could be safely extended to the patients ≥70 y. o.
Awake tracheotomy in a patient with stridor and dyspnoea caused by a sizeable malignant thyroid tumor: a case report and short review of the literature
Authors: Hohn Andreas , Kauliņš Tālis , Hinkelbein Jochen , Kauliņa Krista , Kopp Andreas , Russo Sebastian G. , Kohlen Sigurd , Schröder Stefan 
Published: October 2017

Key Clinical MessageIndividual airway management is mandatory in patients with large goiters undergoing thyroid surgery. Preoperative endoscopic airway evaluation and imaging studies can support clinical decision making. Awake tracheotomy can be an effective and reasonable airway management strategy in such patients.
A Model to Evaluate the Dustiness of Powders and Binary Powder Mixtures
Authors: Parey Matthias , Schmidt Eberhard 
Published: October 2017

AbstractDust emissions of powder handling processes lead to several problems with regard to health, environment, and product quality. Currently, there is no universal method to predict the character and extent of dust release. A model to evaluate the dustiness of powders and binary powder mixtures is introduced and discussed. Disperse characteristics, different particulate material compositions, and effective adhesive forces are considered as the leading factors affecting the dustiness. The outcome of the model allows comparing theoretical dust emissions from different designed powders and predicting the composition of the released dust. The model is demonstrated based on corundum‐blended limestone powder. The study also provides a comparison to experimental data.