bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of Black Men Who Have Sex With Men in Baltimore, Philadelphia, and Washington, D.C.: Geographic Diversity in Socio-Demographics and HIV Transmission Risk
Authors: German Danielle , Brady Kathleen , Kuo Irene , Opoku Jenevieve , Flynn Colin , Patrick Rudy , Park Ju Nyeong , Adams Joella , Carroll Makeda , Simmons Ron , Smith Carlton R. , Davis Wendy W. ,   for the Mid-Atlantic CFAR Consortium
Published: June 2017

Background:
Baltimore, Philadelphia, and Washington, DC are geographically proximate cities with high HIV prevalence, including among black men who have sex with men (BMSM). Using data collected among BMSM in CDC's National HIV Behavioral Surveillance project, we compared socio-demographic characteristics, HIV risk behaviors, and service utilization to explore similarities and differences that could inform local and regional HIV intervention approaches.

Methods:
BMSM were recruited through venue time location sampling, June–December, 2011. Participants completed identical socio-behavioral surveys and voluntary HIV testing. Analyses were conducted among the full sample and those aged 18–24.

Findings:
Participants included 159 (DC), 364 (Baltimore), and 331 (Philadelphia) eligible BMSM. HIV prevalence was 23.1% (DC), 48.0% (Baltimore), 14.6% (Philadelphia) with 30.6%, 69.0%, 33.3% unrecognized HIV infection, respectively. Among BMSM 18–24, HIV prevalence was 11.1% (DC), 38.9% (Baltimore), 9.6% (Philadelphia) with unrecognized HIV infection 0.0%, 73.8%, 60.0% respectively. Compared with the other 2 cities, Baltimore participants were less likely to identify as gay/homosexual; more likely to report unemployment, incarceration, homelessness, sex exchange; and least likely to use the internet for partners. DC participants were more likely to have a college degree and employment. Philadelphia participants were more likely to report gay/homosexual identity, receptive condomless anal sex, having only main partners, and bars/clubs as partner meeting places. Sexually transmitted disease testing was universally low.

Conclusions:
Analyses showed especially high HIV prevalence among BMSM in Baltimore including among young BMSM. Socio-demographic characteristics and HIV infection correlates differed across cities but unrecognized HIV infection and unknown partner status were universally high.
Is Multiple Sclerosis Associated With a Lower Intraocular Pressure?
Authors: Lincoff Norah S. , Buccilli Andrea , Weinstock-Guttman Bianca , Sieminski Sandra , Gandhi Sirin 
Published: June 2017

Objective:
To determine if multiple sclerosis (MS) is associated with lower intraocular pressure (IOP) compared with individuals without MS.

Methods:
Thirty patients with clinically definite MS were identified and a retrospective chart review was conducted. Each patient with MS underwent IOP recording by a single investigator using kinetic applanation tonometry. Measurement of central corneal thickness (CCT) also was obtained. Similarly, 30 study controls were identified and kinetic applanation tonometry and CCT were recorded. Univariate analysis of covariance was conducted to determine a statistically significant difference between IOP between MS and control groups, controlling for age.

Results:
Analyses were adjusted for age and 2 subjects were excluded because of steroid use. The average IOP in MS group was 12.3 mm Hg (right eye = 12.3 mm Hg, left eye = 12.2 mm Hg) and in the control group was 17 mm Hg (right eye = 16.9 mm Hg, left eye = 17 mm Hg). There was a significant effect of presence of MS on IOP accounting for 53% variability in mean IOP (F(1,55) = 60.7; P < 0.001) when compared with the control group.

Conclusions:
This study demonstrated that IOP was significantly lower in patients with MS compared with controls. A more in-depth prospective study design is required, along with further investigation of possible etiologies. Identifying the mechanism of decreased IOP in patients with MS might allow development of new-targeted therapies for the treatment of glaucoma.
Changing geographic patterns and risk factors for avian influenza A(H7N9) infection in China
Authors: Artois Jean , Wang Xiling , Jiang Hui , Qin Ying , Pearcy Morgan , Lai Shengjie , Shi Yujing , Zhang Juanjuan , Peng Zhibin , Zheng Jiandong , He Yangni , Dhingra Madhur S , Dobschuetz Sophie von , Guo Fusheng , Martin Vincent , Kalpravidh Wantanee , Claes Filip , Robinson Timothy , Hay Simon I. , Xiao Xiangming , Feng Luzhao , Gilbert Marius , Yu Hongjie 
Published: June 2017

AbstractThe 5thepidemic wave in 2016-2017 of avian influenza A(H7N9) virus in China caused more human cases than any previous waves but the factors that may explain the recent range expansion and surge in incidence remain unknown. We investigated the effect of anthropogenic, poultry and wetland information and of market closures on all epidemic waves (1-5). Poultry predictor variables recently became much more important than before, supporting the assumption of much wider H7N9 transmission in the chicken reservoir, that could be linked to increases in pathogenicity. We show that the future range expansion of H7N9 to northern China may translate into a higher risk of coinciding peaks with those of seasonal influenza, leading to a higher risk of reassortments. Live-poultry market closures are showed to be effective in reducing the local incidence rates of H7N9 human cases, but should be paired with other prevention and control measures to prevent transmission.
Performance Of Children With Autism In Parent-Administered Cognitive And Language Exercises
Authors: Dunn Rita , Elgart Jonah , Lokshina Lisa , Faisman Alexander , Khokhlovich Edward , Gankin Yuriy , Vyshedskiy Andrey 
Published: June 2017

AbstractThere is a broad scientific consensus that early and intensive therapy has the greatest chance of positive impact on an individual with autism spectrum disorder (ASD). However, the availability, quality, and general funding for early intervention programs is often lacking, leaving newly diagnosed children without adequate and sufficient therapy during the most critical early period of their development. Parent-administered iPad-assisted therapy has the potential to reduce the gap between the amount of therapy recommended for children with ASD and the amount they receive. However it is unclear how ASD severity and age influence a child’s ability to engage with and learn from computerized cognitive exercises. In this manuscript, we describe data from a tablet-based therapeutic application administered by parents to 1,514 young children with ASD over the course of four to twelve months. We report that older children and children with milder forms of ASD performed better and progressed faster in cognitive and language exercises. However, most children were able to engage with and learn from exercises independent of their age or ASD severity. This data confirm that tablet-based cognitive and language exercises can be successfully administered by parents to children as young as two years of age over the course of many months independent of ASD severity.
The integrated stress response pathway activates 4E-BP to bias mRNA translation and boost antimicrobial peptide synthesis in response to bacterial infection
Authors: Vasudevan Deepika , Clark Nicholas K. , Sam Jessica , Ueberheide Beatrix , Marr Michael T. , Ryoo Hyung Don 
Published: June 2017

SummaryPathogenic bacterial infection imposes considerable cellular stress on the host and often leads to attenuation of mRNA translation. In this translation-suppressive environment, it is unclear how the host synthesizes various antimicrobial peptides (AMPs) to mount innate immune response. Here, we useDrosophilaas a model to demonstrate that AMP production during infection relies on a translation bias mechanism mediated by the inhibitor of cap-dependent translation 4E-BP (DrosophilaThor), and the AMP 5’UTRs that can undergo cap-independent translation. We found that 4E-BP is induced upon infection with the pathogenic bacteriaEcc15by the stress-responsive transcription factor ATF4, and its upstream kinase GCN2. Moreover, loss ofgcn2, atf4or4e-bpcompromised immunity againstEcc15.In 4E-BP mutants, the transcriptional induction of AMPs after infection was unaffected, while the protein levels of AMPs were substantially reduced in their hemolymph. Analysis of the 5’UTRs of AMPs using cell-based bicistronic reporters andin vitrotranslation analysis indicated that AMPs are translated in a cap-independent mechanism. Analysis of bicistronic reporters in the presence of 4E-BP indicate that infection enhances cap-independent translational activity associated with AMP 5’UTRs, accounting for enhanced AMP translation during infection.Highlights4E-BP is transcriptionally induced by GCN2/ATF signaling in response to bacterial infection4E-BP mutants show unaltered antimicrobial peptide (AMP) transcript levels, but have reduced AMP translationAMP 5’UTRs are translated cap-independentlyTranslation bias by 4E-BP drives cap-independent AMP translation
Engagement rules that underpin DBL-DARC interactions for ingress ofPlasmodium knowlesiandPlasmodium vivaxinto human erythrocytes
Authors: Yogavel Manickam , Jamwal Abhishek , Gupta Swati , Sharma Amit 
Published: June 2017

SummaryThe molecular mechanisms by whichP. knowlesiandP. vivaxinvade human red blood cells have long been studied. Malaria parasite erythrocytic stages comprise of repeated bursts of parasites via cyclical invasion of host RBCs using dedicated receptor-ligand interactions. A family of erythrocyte-binding proteins (EBPs) fromP. knowlesiandP. vivaxattach to human Duffy antigen receptor for chemokines (DARC) via their Duffy binding-like domains (Pv-DBL andPk-DBL respectively) for invasion. Here, we provide a comprehensive overview that presents new insights on the atomic resolution interactions that underpin the binding of human DARC withPk/Pv-DBLs. Based on extensive structural and biochemical data, we provide a novel, testable and overarching interaction model that rationalizes even contradictory pieces of evidence that have so far existed in the literature onPk/Pv-DBL/DARC binding determinants. We address the conundrum of how parasite-encodedPk/Pv-DBLs recognize human DARC via its two sulfated tyrosine residues. We collate evidence for two distinct DARC integration sites onPk/Pv-DBLs that together likely engage the DARC’s sulfated extracellular domain. These analyses are important for both malaria vaccine and inhibitor development efforts that are targeted at abrogatingPk/Pv-DBL/DARC coupling as one avenue to prevent invasion ofP. vivaxinto human red blood cells.
Efficient numerical simulation of injection mold filling with the lattice Boltzmann method
Authors: Deng Lin , Liang Junjie , Zhang Yun , Zhou Huamin , Huang Zhigao 
Published: June 2017

PurposeLattice Boltzmann method (LBM) has made great success in computational fluid dynamics, and this paper aims to establish an efficient simulation model for the polymer injection molding process using the LBM. The study aims to validate the capacity of the model for accurately predicting the injection molding process, to demonstrate the superior numerical efficiency in comparison with the current model based on the finite volume method (FVM).Design/methodology/approachThe study adopts the stable multi-relaxation-time scheme of LBM to model the non-Newtonian polymer flow during the filling process. The volume of fluid method is naturally integrated to track the movement of the melt front. Additionally, a novel fractional-step thermal LBM is used to solve the convection-diffusion equation of the temperature field evolution, which is of high Peclet number. Through various simulation cases, the accuracy and stability of the present model are validated, and the higher numerical efficiency verified in comparison with the current FVM-based model.FindingsThe paper provides an efficient alternative to the current models in the simulation of polymer injection molding. Through the test cases, the model presented in this paper accurately predicts the filling process and successfully reproduces several characteristic phenomena of injection molding. Moreover, compared with the popular FVM-based models, the present model shows superior numerical efficiency, more fit for the future trend of parallel computing.Research limitations/implicationsLimited by the authors’ hardware resources, the programs of the present model and the FVM-based model are run on parallel up to 12 threads, which is adequate for most simulations of polymer injection molding. Through the tests, the present model has demonstrated the better numerical efficiency, and it is recommended for the researcher to investigate the parallel performance on even larger-scale parallel computing, with more threads.Originality/valueTo the authors’ knowledge, it is for the first time that the lattice Boltzmann method is applied in the simulation of injection molding, and the proposed model does obviously better in numerical efficiency than the current popular FVM-based models.
Analysis of repetitive and near-repetitive structures by transformation to equivalent circulant structures
Authors: Kaveh A. , Rahami H. , Jodaki A. 
Published: June 2017

Purpose
There are many structures that have a repetitive pattern. If a relationship can be established between a repetitive structure and a circulant structure, then the repetitive structure can be analyzed by using the properties of the corresponding circulant structure. The purpose of this paper is to develop such a transformation.

Design/methodology/approach
A circulant matrix has certain properties that can be used to reduce the complexity of the analysis. In this paper, repetitive and near-repetitive structures are transformed to circulant structures by adding and/or eliminating some elements of the structure. Numerical examples are provided to show the efficiency of the present method.

Findings
A transformation is established between a repetitive structure and a circulant structure, and the analysis of the repetitive structure is performed by using the properties of the corresponding circulant structure.

Originality/value
Repetitive and near-repetitive structures are transformed to circulant structures, and the complexity of the analysis of the former structures is reduced by analyzing the latter structures.
Coupling of 2D discretized Peridynamics with a meshless method based on classical elasticity using switching of nodal behaviour
Authors: Shojaei Arman , Zaccariotto Mirco , Galvanetto Ugo 
Published: June 2017

Purpose
The paper aims to use a switching technique which allows to couple a nonlocal bond-based Peridynamic approach to the Meshless Local Exponential Basis Functions (MLEBF) method, based on classical continuum mechanics, to solve planar problems.

Design/methodology/approach
The coupling has been achieved in a completely meshless scheme. The domain is divided in three zones: one in which only Peridynamics is applied, one in which only the meshless method is applied and a transition zone where a gradual transition between the two approaches takes place.

Findings
The new coupling technique generates overall grids that are not affected by ghost forces. Moreover, the use of the meshless approach can be limited to a narrow boundary region of the domain, and in this way, it can be used to remove the “surface effect” from the Peridynamic solution applied to all internal points.

Originality/value
The current study paves the road for future studies on dynamic and static crack propagation problems.
A numerical study of thermo-diffusion, diffusion-thermo and chemical reaction effects on flow of a micropolar fluid in an asymmetric channel with dilating and contracting permeable walls
Authors: Mohyud-din Syed Tauseef , Ahmed Naveed , Khan Umar , Rashidi Mohammad Mehdi 
Published: June 2017

Purpose
The purpose of this study is to analyze thermo-diffusion and diffusion-thermo effects, combined with first-order chemical reaction, in the flow of a micropolar fluid through an asymmetric channel with porous boundaries. Suction/injection velocities of upper and lower walls are taken to be different from each other. The channel exhibits a parting or embracing motion and the fluid enters, or leaves, the channel because of suction/injection through the permeable walls.

Design/methodology/approach
The solution of the problem is obtained by using the fourth-order Runge-Kutta method combined with the shooting technique.

Findings
The asymmetric nature of the channel that is caused by the different permeabilities of the walls deeply influences the flow. The temperature of the fluid rises significantly by increasing the absolute value of A for both Case I and Case II. While, for the concentration profile, the concentration drops near the lower vicinity of the center in Case I, and, it falls near the lower wall of the channel in Case II. Stronger Dufour effects increase the temperature of the fluid except for Case 1 at the center of the channel and for Case II in lower quarter of the channel.

Originality/value
It is confirmed that the presented work is original and is not under consideration by any other journal.
Thermo-mechanical coupling particle simulation of three-dimensional large-scale non-isothermal problems
Authors: Xia Ming 
Published: June 2017

Purpose
The main purpose of this paper is to present a comprehensive upscale theory of the thermo-mechanical coupling particle simulation for three-dimensional (3D) large-scale non-isothermal problems, so that a small 3D length-scale particle model can exactly reproduce the same mechanical and thermal results with that of a large 3D length-scale one.

Design/methodology/approach
The objective is achieved by following the scaling methodology proposed by Feng and Owen (2014).

Findings
After four basic physical quantities and their similarity-ratios are chosen, the derived quantities and its similarity-ratios can be derived from its dimensions. As the proposed comprehensive 3D upscale theory contains five similarity criteria, it reveals the intrinsic relationship between the particle-simulation solution obtained from a small 3D length-scale (e.g. a laboratory length-scale) model and that obtained from a large 3D length-scale (e.g. a geological length-scale) one. The scale invariance of the 3D interaction law in the thermo-mechanical coupled particle model is examined. The proposed 3D upscale theory is tested through two typical examples. Finally, a practical application example of 3D transient heat flow in a solid with constant heat flux is given to illustrate the performance of the proposed 3D upscale theory in the thermo-mechanical coupling particle simulation of 3D large-scale non-isothermal problems. Both the benchmark tests and application example are provided to demonstrate the correctness and usefulness of the proposed 3D upscale theory for simulating 3D non-isothermal problems using the particle simulation method.

Originality/value
The paper provides some important theoretical guidance to modeling 3D large-scale non-isothermal problems at both the engineering length-scale (i.e. the meter-scale) and the geological length-scale (i.e. the kilometer-scale) using the particle simulation method directly.
Distortion-resistant and locking-free eight-node elements effectively capturing the edge effects of Mindlin–Reissner plates
Authors: Bao Yi , Cen Song , Li Chenfeng 
Published: June 2017

PurposeA simple shape-free high-order hybrid displacement function element method is presented for precise bending analyses of Mindlin–Reissner plates. Three distortion-resistant and locking-free eight-node plate elements are proposed by utilizing this method.Design/methodology/approachThis method is based on the principle of minimum complementary energy, in which the trial functions for resultant fields are derived from two displacement functions,Fandf, and satisfy all governing equations. Meanwhile, the element boundary displacements are determined by the locking-free arbitrary order Timoshenko’s beam functions. Then, three locking-free eight-node, 24-DOF quadrilateral plate-bending elements are formulated: HDF-P8-23β for general cases, HDF-P8-SS1 for edge effects along soft simply supported (SS1) boundary and HDF-P8-FREE for edge effects along free boundary.FindingsThe proposed elements can pass all patch tests, exhibit excellent convergence and possess superior precision when compared to all other existing eight-node models, and can still provide good and stable results even when extremely coarse and distorted meshes are used. They can also effectively solve the edge effect by accurately capturing the peak value and the dramatical variations of resultants near the SS1 and free boundaries. The proposed eight-node models possess potential in engineering applications and can be easily integrated into commercial software.Originality/valueThis work presents a new scheme, which can take the advantages of both analytical and discrete methods, to develop high-order mesh distortion-resistant Mindlin–Reissner plate-bending elements.
Free vibration of moderately thick functionally graded parabolic and circular panels and shells of revolution with general boundary conditions
Authors: Wang Qingshan , Shi Dongyan , Liang Qian , Pang Fuzhen 
Published: June 2017

Purpose
The purpose of this work is to apply the Fourier–Ritz method to study the vibration behavior of the moderately thick functionally graded (FG) parabolic and circular panels and shells of revolution with general boundary conditions.

Design/methodology/approach
The modified Fourier series is chosen as the basis function of the admissible functions of the structure to eliminate all the relevant discontinuities of the displacements and their derivatives at the edges, and the vibration behavior is solved by means of the Ritz method. The complete shells of revolution can be achieved by using the coupling spring technique to imitate the kinematic compatibility and physical compatibility conditions of FG parabolic and circular panels at the common meridian of θ = 0 and 2π. The convergence and accuracy of the present method are verified by other contributors.

Findings
Some new results of FG panels and shells with elastic restraints, as well as different geometric and material parameters, are presented and the effects of the elastic restraint parameters, power-law exponent, circumference angle and power-law distributions on the free vibration characteristic of the panels are also presented, which can be served as benchmark data for the designers and engineers to avoid the unpleasant, inefficient and structurally damaging resonant.

Originality/value
The paper could provide the reference for the research about the moderately thick FG parabolic and circular panels and shells of revolution with general boundary conditions. In addition, the change of the boundary conditions can be easily achieved by just varying the stiffness of the boundary restraining springs along all the edges of panels without making any changes in the solution procedure.