bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Proposed New Approach for Groundwater Resources Assessment in India
Authors: Chatterjee Rana , Ray Ranjan Kumar 
Published: September 2016

Abstract:
Assessment of groundwater resources in India is guided by National Water Policy (1987, 2002) which states that groundwater resources can be exploited only up to its recharge limit. The methodology for groundwater resources assessment in India is broadly based on Ground Water Resources Estimation Methodology, 1997 and it involves assessment of annual replenishable groundwater resources (recharge), annual groundwater draft (utilization) and the percentage of utilization with respect to recharge (stage of development). The assessment units (blocks/watersheds) are categorized based on stage of groundwater development (utilization) and the long term water level trend. The present methodology though useful in identification and prioritization of areas for groundwater management, falls short of addressing several critical issues like spatial and temporal variation of groundwater availability within the aquifer, accessibility of groundwater resources and quality of groundwater. This paper introduces a new categorisation scheme considering the above issues. The proposed scheme takes into account four criteria, viz. (i) stage of exploitation, (ii) extractability factor, (iii) temporal availability factor and (iv) quality factor. In comparison to the existing method used for categorisation, the proposed approach is more inclusive. The methodology is also equally suitable for both alluvial and hard rock terrain since it takes into consideration the variable characteristics of different types of aquifers and convergence of quantitative and qualitative assessment. The categorisation proposed here involves GIS based integration of different parameters/themes. This allows better representation of spatial variability. The proposed methodology is demonstrated in this paper taking a case study from a hard rock terrain in central India.
Geochemistry of the Sandstones of Punagarh Basin: Implications for Two Source Terranes and Arabian - Nubian Connection of Aravalli Craton?
Authors: Khan Tavheed , Khan M. Shamim 
Published: September 2016

Abstract:
Sandstones of Punagarh basin of Trans Aravalli region, NW Indian shield were analyzed for their major and trace element contents in conjunction with petrographic modes. The Punagarh basin comprises four formations (Sojat, Bambolai, Khamal and Sowania), amongst which the Sojat Formation in uncoformable contact with overlying formations, is significantly older and enjoys separate status as rest of the formations constitute Punagarh Group. Petrographic attributes suggest that Sojat sandstones contain distinct modal abundances like high content of quartz and low content of feldspar, mica, matrix, rock fragments and cement. In general there is a decrease in the average modal abundance of quartz and mica with concomitant increase of feldspar, chert and rock fragments from base to top in Punagarh sandstones. Sojat sandstones are also geochemically distinct as they possess high SiO2/Al2O3, Th/U and Cr/Th ratios coupled with lowest Na2O/K2O ratio and Zr content, least fractionated LREE, more fractionated HREE and largest Eu* anomaly compared to Punagarh sandstones. The weathering indices suggest intense chemical weathering for Sojat sandstones and low to moderate for Punagarh sandstones. Compositionally all the sandstones of the Punagarh basin come under the category of quartzarenite. Compared to PAAS and UCC, both suite of sandstones are generally depleted in REE, HFSE (with exception of Zr, Hf and Ta), and enriched in ferromagnesian trace elements particularly Cr and Co. The chemical data indicate that the sediments were derived from the source(s) of mixed felsic - mafic composition, with the former being dominant. The source rocks were granites, TTG, basalts, and rhyolites. The Sojat sandstones owe their source form Archean crust while Punagarh sandstones got detritus from Mesoproterozic crust. Immobile element ratios and REE abundances of Sojat sandstones closely match with Paleoproterozoic metagreywackes of Ghana of African craton while Punagarh sandstones show near geochemical characteristic with Gogunda, Kumbalgarh and Vindhyan quartzites of Aravalli craton. This geochemical similarity of Sojat sandstones provides credence to the hypothesis that Trans – Aravalli region of India had been an integral part of Arabian - Nubian shield. The chemical data advocate the deposition of these sandstones in a tectonic setting comparable to modern back arc setting.
The Right to Liberty in European Union Law and Mutual Recognition in Criminal Matters
Authors: MANCANO Leandro 
Published: September 2016

AbstractThis article analyses the interaction between the application of mutual recognition in criminal matters and the right to liberty. The main argument is that the current content of the right to liberty in EU law is unsuitable for mutual recognition procedures. As for the structure of this article, firstly, the main features of mutual recognition as a method of inter-state cooperation in criminal matters are outlined. Secondly, the approach of the European Union (especially the Court of Justice) to the right to liberty is clarified. Thirdly, four mutual recognition instruments are analysed in light of the right to liberty: namely, the Framework Decisions on the European Arrest Warrant; the Transfer of Prisoners; the Probation Measures; and the European Supervision Order (ESO). The assessment confirms that the higher level of automaticity in judicial cooperation introduced by mutual recognition requires a rethink of the existing understanding of the right to liberty in EU law.
Trends in Medication Use Over 11 Years in Patients Presenting to a Rural and Remote Memory Clinic
Authors: Verity Ryan , Kirk Andrew , Morgan Debra , Karunanayake Chandima 
Published: September 2016

AbstractBackground: Anticholinergic and sedating medications are generally contraindicated in those with cognitive decline. We examined trends in medication use by patients at initial presentation to a rural and remote memory clinic (RRMC) between March 2004 and June 2015 to determine whether patterns of medication use have changed. Methods: The first 444 patients seen at the RRMC between 2004 and 2015 were included in this analysis. Medication lists were collected at the patient’s initial visit, and it was noted whether patients were taking anticholinergic or potentially sedating drugs. Statistical analysis (Spearman’s correlation) was conducted to examine trends in medication use over time. Results: Patients were on a mean of 5.18 medications (standard deviation, 3.46). Ninety-one patients (20.5%) were taking at least one anticholinergic medication. There was a decline (25.0% in 2004 to 12.5% in 2014) in percentage of patients presenting with anticholinergic medications over the 11 years of this study (Spearman’s correlation coefficient =−0.64, p=0.035). The prevalence of drugs acting on the central nervous system trended toward an increase, but this was not statistically significant. Sixty-three patients (14.2%) presented to the RRMC already taking a cholinesterase inhibitor. Conclusions: The most encouraging statistic to come from this study is a decline in anticholinergic medication use in this rural population. Prescribers must be properly informed to ensure that the number of medications per patient does not continue to rise, that medications are used only as necessary, and that potentially deleterious medications are avoided.
Spontaneous Thrombosis of an Unruptured Saccular Aneurysm Causing MCA Infarction
Authors: Fomenko Anton , Kaufmann Anthony M. 
Published: September 2016

AbstractSpontaneous complete thrombosis of an unruptured intracranial aneurysm leading to ischemic stroke is rare. We present a case of a 56-year-old man who suffered an acute left middle cerebral artery (MCA) infarction, attributable to complete thrombosis of an unruptured saccular MCA bifurcation aneurysm with occlusion of the parent artery. The presenting hemiparesis and aphasia partially improved over a long hospital rehabilitation stay. Follow-up imaging demonstrated no recanalization of the aneurysm or parent vessels. To the best of our knowledge this is the first documented case of isolated MCA territory infarction due to complete spontaneous thrombosis of a saccular aneurysm.
Overall recession and mass budget of Gangotri Glacier, Garhwal Himalayas, from 1965 to 2015 using remote sensing data
Authors: BHATTACHARYA ATANU , BOLCH TOBIAS , MUKHERJEE KRITI , PIECZONKA TINO , KROPÁČEK JAN , BUCHROITHNER MANFRED F. 
Published: September 2016

ABSTRACTThinning rates for the debris-covered Gangotri Glacier and its tributary glaciers during the period 1968–2014, length variation and area vacated at the snout from 1965 to 2015, and seasonal variation of ice-surface velocity for the last two decades have been investigated in this study. It was found that the mass loss of Gangotri and its tributary glaciers was slightly less than those reported for other debris-covered glaciers in the Himalayan regions. The average velocity during 2006–14 decreased by ~6.7% as compared with that during 1993–2006. The debris-covered area of the main trunk of Gangotri Glacier increased significantly from 1965 until 2015 with the maximum rate of increase (0.8 ± 0.2 km2 a−1) during 2006–15. The retreat (~9.0 ± 3.5 m a−1) was less in recent years (2006–2015) but the down-wasting (0.34 ± 0.2 m a−1) in the same period (2006–2014) was higher than that (0.20 ± 0.1 m a−1) during 1968–2006. The study reinforced the established fact that the glacier length change is a delayed response to climate change and, in addition, is affected by debris cover, whereas glacier mass balance is a more direct and immediate response. Therefore, it is recommended to study the glacier mass balance and not only the glacier extent, to conclude about a glacier's response to climate change.
Flavonoid intake from vegetables and fruits is inversely associated with colorectal cancer risk: a case–control study in China
Authors: Xu Ming , Chen Yu-Ming , Huang Jing , Fang Yu-Jing , Huang Wu-Qing , Yan Bo , Lu Min-Shan , Pan Zhi-Zhong , Zhang Cai-Xia 
Published: September 2016

AbstractFlavonoids may play an important role in the protective effects of vegetables, fruits and tea against colorectal cancer. However, associations between flavonoids and colorectal cancer risk are inconsistent, and a few studies have evaluated the effect of flavonoids from different dietary sources separately. This study aimed to evaluate associations of flavonoids intake from different dietary sources with colorectal cancer risk in a Chinese population. From July 2010 to December 2015, 1632 eligible colorectal cancer cases and 1632 frequency-matched controls (age and sex) completed in-person interviews. A validated FFQ was used to estimate dietary flavonoids intake. Multivariate logistical regression models were used to calculate the OR and 95 % CI of colorectal cancer risk after adjusting for various confounders. No significant association was found between total flavonoids and colorectal cancer risk, with an adjusted OR of 1·06 (95 % CI 0·85, 1·32) comparing the highest with the lowest quartile. Anthocyanidins, flavanones and flavones intakes from total diet were found to be inversely associated with colorectal cancer risk. Compared with the lowest quartile, the adjusted OR for the highest quartile were 0·80 (95 % CI 0·64, 1·00) for anthocyanidins, 0·28 (95 % CI 0·22, 0·36) for flavanones and 0·54 (95 % CI 0·43, 0·67) for flavones. All subclasses of flavonoids from vegetables and fruits were inversely associated with colorectal cancer. However, no significant association was found between tea flavonoids and colorectal cancer risk. These data indicate that specific flavonoids, specifically flavonoids from vegetables and fruits, may be linked with the reduced risk of colorectal cancer.
Cognitive–behaviour therapy for post-traumatic stress in schizophrenia. A randomized controlled trial
Authors: Steel C. , Hardy A. , Smith B. , Wykes T. , Rose S. , Enright S. , Hardcastle M. , Landau S. , Baksh M. F. , Gottlieb J. D. , Rose D. , Mueser K. T. 
Published: September 2016

BackgroundThere is limited evidence for effective interventions in the treatment of post-traumatic stress symptoms within individuals diagnosed with schizophrenia. Clinicians have concerns about using exposure treatments with this patient group. The current trial was designed to evaluate a 16-session cognitive restructuring programme, without direct exposure, for the treatment of post-traumatic stress symptoms specifically within individuals diagnosed with schizophrenia.MethodA multicentre randomized controlled single-blinded trial with assessments at 0 months, 6 months (post-treatment) and 12 months (follow-up) was conducted. A total of 61 participants diagnosed with schizophrenia and exhibiting post-traumatic stress symptoms were recruited. Those randomized to treatment were offered up to 16 sessions of cognitive–behaviour therapy (CBT, including psychoeducation, breathing training and cognitive restructuring) over a 6-month period, with the control group offered routine clinical services. The main outcome was blind rating of post-traumatic stress symptoms using the Clinician Administered PTSD Scale for Schizophrenia. Secondary outcomes were psychotic symptoms as measured by the Positive and Negative Symptom Scale and the Psychotic Symptom Rating Scale.ResultsBoth the treatment and control groups experienced a significant decrease in post-traumatic stress symptoms over time but there was no effect of the addition of CBT on either the primary or secondary outcomes.ConclusionsThe current trial did not demonstrate any effect in favour of CBT. Cognitive restructuring programmes may require further adaptation to promote emotional processing of traumatic memories within people diagnosed with a psychotic disorder.
What explains rare and conspicuous colours in a snail? A test of time-series data against models of drift, migration or selection
Authors: Johannesson K , Butlin R K 
Published: September 2016

AbstractIt is intriguing that conspicuous colour morphs of a prey species may be maintained at low frequencies alongside cryptic morphs. Negative frequency-dependent selection by predators using search images (‘apostatic selection’) is often suggested without rejecting alternative explanations. Using a maximum likelihood approach we fitted predictions from models of genetic drift, migration, constant selection, heterozygote advantage or negative frequency-dependent selection to time-series data of colour frequencies in isolated populations of a marine snail (Littorina saxatilis), re-established with perturbed colour morph frequencies and followed for >20 generations. Snails of conspicuous colours (white, red, banded) are naturally rare in the study area (usually <10%) but frequencies were manipulated to levels of ~50% (one colour per population) in 8 populations at the start of the experiment in 1992. In 2013, frequencies had declined to ~15–45%. Drift alone could not explain these changes. Migration could not be rejected in any population, but required rates much higher than those recorded. Directional selection was rejected in three populations in favour of balancing selection. Heterozygote advantage and negative frequency-dependent selection could not be distinguished statistically, although overall the results favoured the latter. Populations varied idiosyncratically as mild or variable colour selection (3–11%) interacted with demographic stochasticity, and the overall conclusion was that multiple mechanisms may contribute to maintaining the polymorphisms.
A conserved influenza A virus nucleoprotein code controls specific viral genome packaging
Authors: Moreira Étori Aguiar , Weber Anna , Bolte Hardin , Kolesnikova Larissa , Giese Sebastian , Lakdawala Seema , Beer Martin , Zimmer Gert , García-Sastre Adolfo , Schwemmle Martin , Juozapaitis Mindaugas 
Published: September 2016

AbstractPackaging of the eight genomic RNA segments of influenza A viruses (IAV) into viral particles is coordinated by segment-specific packaging sequences. How the packaging signals regulate the specific incorporation of each RNA segment into virions and whether other viral or host factors are involved in this process is unknown. Here, we show that distinct amino acids of the viral nucleoprotein (NP) are required for packaging of specific RNA segments. This was determined by studying the NP of a bat influenza A-like virus, HL17NL10, in the context of a conventional IAV (SC35M). Replacement of conserved SC35M NP residues by those of HL17NL10 NP resulted in RNA packaging defective IAV. Surprisingly, substitution of these conserved SC35M amino acids with HL17NL10 NP residues led to IAV with altered packaging efficiencies for specific subsets of RNA segments. This suggests that NP harbours an amino acid code that dictates genome packaging into infectious virions.
Spin–orbit coupled molecular quantum magnetism realized in inorganic solid
Authors: Park Sang-Youn , Do S.-H. , Choi K.-Y. , Kang J.-H. , Jang Dongjin , Schmidt B. , Brando Manuel , Kim B.-H. , Kim D.-H. , Butch N. P. , Lee Seongsu , Park J.-H. , Ji Sungdae 
Published: September 2016

AbstractMolecular quantum magnetism involving an isolated spin state is of particular interest due to the characteristic quantum phenomena underlying spin qubits or molecular spintronics for quantum information devices, as demonstrated in magnetic metal–organic molecular systems, the so-called molecular magnets. Here we report the molecular quantum magnetism realized in an inorganic solid Ba3Yb2Zn5O11 with spin–orbit coupled pseudospin-½ Yb3+ ions. The magnetization represents the magnetic quantum values of an isolated Yb4 tetrahedron with a total (pseudo)spin 0, 1 and 2. Inelastic neutron scattering results reveal that a large Dzyaloshinsky–Moriya interaction originating from strong spin–orbit coupling of Yb 4f is a key ingredient to explain magnetic excitations of the molecular magnet states. The Dzyaloshinsky–Moriya interaction allows a non-adiabatic quantum transition between avoided crossing energy levels, and also results in unexpected magnetic behaviours in conventional molecular magnets.
The ONDRISeq panel: custom-designed next-generation sequencing of genes related to neurodegeneration
Authors: Farhan Sali M K , Dilliott Allison A , Ghani Mahdi , Sato Christine , Liang Eric , Zhang Ming , McIntyre Adam D , Cao Henian , Racacho Lemuel , Robinson John F , Strong Michael J , Masellis Mario , St George-Hyslop Peter , Bulman Dennis E , Rogaeva Ekaterina , Hegele Robert A ,   ONDRI Investigators
Published: September 2016

AbstractThe Ontario Neurodegenerative Disease Research Initiative (ONDRI) is a multimodal, multi-year, prospective observational cohort study to characterise five diseases: (1) Alzheimer’s disease (AD) or amnestic single or multidomain mild cognitive impairment (aMCI) (AD/MCI); (2) amyotrophic lateral sclerosis (ALS); (3) frontotemporal dementia (FTD); (4) Parkinson’s disease (PD); and (5) vascular cognitive impairment (VCI). The ONDRI Genomics subgroup is investigating the genetic basis of neurodegeneration. We have developed a custom next-generation-sequencing-based panel, ONDRISeq that targets 80 genes known to be associated with neurodegeneration. We processed DNA collected from 216 individuals diagnosed with one of the five diseases, on ONDRISeq. All runs were executed on a MiSeq instrument and subjected to rigorous quality control assessments. We also independently validated a subset of the variant calls using NeuroX (a genome-wide array for neurodegenerative disorders), TaqMan allelic discrimination assay, or Sanger sequencing. ONDRISeq consistently generated high-quality genotyping calls and on average, 92% of targeted bases are covered by at least 30 reads. We also observed 100% concordance for the variants identified via ONDRISeq and validated by other genomic technologies. We were successful in detecting known as well as novel rare variants in 72.2% of cases although not all variants are disease-causing. Using ONDRISeq, we also found that the APOE E4 allele had a frequency of 0.167 in these samples. Our optimised workflow highlights next-generation sequencing as a robust tool in elucidating the genetic basis of neurodegenerative diseases by screening multiple candidate genes simultaneously.
Beyond patient-centered care: person-centered care for Parkinson’s disease
Authors: Buetow Stephen A , Martínez-Martín Pablo , Hirsch Mark A , Okun Michael S 
Published: September 2016

AbstractInterest has grown in centering Parkinson’s disease (PD) care provision on the welfare of the patient with PD. By putting the welfare of patients first, this patient-centric focus tends to subordinate the welfare of others including clinicians and carers. A possible solution is person-centered care. Rather than remove the spotlight from the patients, it widens that light to illuminate moral interests of all healthcare participants as persons whose welfare is interdependent. It assumes that unwellness among clinicians, for example, can impact the quality of the PD care they provide, such that caring for clinicians may also optimize the welfare of persons with PD. For PD, we suggest how the two models differ and why these differences are important to understand and act on to optimize benefit for participating stakeholders.
Ultra-low thermal conductivities in large-area Si-Ge nanomeshes for thermoelectric applications
Authors: Perez-Taborda Jaime Andres , Muñoz Rojo Miguel , Maiz Jon , Neophytou Neophytos , Martin-Gonzalez Marisol 
Published: September 2016

AbstractIn this work, we measure the thermal and thermoelectric properties of large-area Si0.8Ge0.2 nano-meshed films fabricated by DC sputtering of Si0.8Ge0.2 on highly ordered porous alumina matrices. The Si0.8Ge0.2 film replicated the porous alumina structure resulting in nano-meshed films. Very good control of the nanomesh geometrical features (pore diameter, pitch, neck) was achieved through the alumina template, with pore diameters ranging from 294 ± 5nm down to 31 ± 4 nm. The method we developed is able to provide large areas of nano-meshes in a simple and reproducible way, being easily scalable for industrial applications. Most importantly, the thermal conductivity of the films was reduced as the diameter of the porous became smaller to values that varied from κ = 1.54 ± 0.27 W K−1m−1, down to the ultra-low κ = 0.55 ± 0.10 W K−1m−1 value. The latter is well below the amorphous limit, while the Seebeck coefficient and electrical conductivity of the material were retained. These properties, together with our large area fabrication approach, can provide an important route towards achieving high conversion efficiency, large area, and high scalable thermoelectric materials.
Design and construction of a spin-wave lens
Authors: Toedt Jan-Niklas , Mundkowski Mark , Heitmann Detlef , Mendach Stefan , Hansen Wolfgang 
Published: September 2016

AbstractIn this work, we present the focusing of a Damon-Eshbach wave in a Ni80Fe20 film by a shaped, discrete transition of the film thickness. We devised an algorithm to determine the required shape of a spin-wave lens. Due to the anisotropy three geometries qualify as plano-convex lenses. One lens geometry has been realized experimentally and the emitted spin-wave pattern is investigated by time-resolved scanning Kerr microscopy.