bluuebunny/crossref_metadata_2025_split huggingface dataset:
NIVELES SANGUÍNEOS DE BIOMARCADORES DE DAÑO GENÉTICO EN ERITROCITOS DE Lepidochelys olivacea (Cheloniidae) EN COLOMBIA
Authors: Quiroz Herrera Victor Hugo , Palacio Baena Jaime 
Published: August 2017

Esta investigación se realizó en el municipio de Bahía Solano, Colombia y tuvo como objetivos: 1) detectar la circulación de eritrocitos con lesiones nucleares en 55 hembras adultas de tortuga golfina (Lepidochelys olivacea), empleando la inmunotinción de naranja de acridina y 2) correlacionar sus frecuencias con aspectos biométricos y fisiológicos. Se determinó una frecuencia de eritrocitos con micronúcleos (EMN) de 0,6 ± 0,6 y de protuberancias nucleares (EPN) de 2,1 ± 1,9. Mediante un análisis multivariado a través de la correlación de Pearson y de Kruskal-Wallis (p<0,05), no se encontró ninguna correlación positiva entre el nivel de frecuencia de EPN ni de EMN con los parámetros biométricos y fisiológicos evaluados. Se estableció una diferencia estadísticamente significativa (p= 0,035) entre las frecuencias de EPN y de EMN. Los resultados hallados indican que esta especie presenta eritrocitos circulantes con los daños nucleares mencionados y reporta por primera vez la presencia de estrés genotóxico para la especie en Colombia. Así mismo, brinda información clave para investigaciones posteriores en el área de la ecotoxicología de especies marinas amenazadas.
MURCIÉLAGOS DISPERSORES DE SEMILLAS EN GRADIENTES SUCESIONALES DE LA ORINOQUIA (SAN MARTÍN, META, COLOMBIA)
Authors: Casallas-Pabón Diego , Calvo-Roa Nathaly , Rojas-Robles Rosario 
Published: August 2017

La dispersión de semillas por fauna juega un papel fundamental en la reproducción vegetal. Los murciélagos son unos de los dispersores de semillas más importantes en los ecosistemas neotropicales. El objetivo en esta investigación fue describir la comunidad de murciélagos y las semillas que potencialmente dispersan, en el gradiente sucesional (sabana, arbustal, borde de bosque y bosque ripario), de una localidad de la altillanura colombiana. Se midió abundancia, riqueza, diversidad de murciélagos y las semillas de sus heces. Se capturaron 534 individuos pertenecientes a cuatro familias y 39 especies. Las especies más abundantes fueron Carollia perspicillata, Artibeus obscurus y Molossus molossus. C. perspicillata y A. obscurus presentaron los mayores valores en el índice de dispersión de semillas (DII). Los registros pertenecen a seis gremios, siendo más abundantes los frugívoros (sedentarios y nómadas). El hábitat con mayor abundancia y riqueza de especies de murciélagos fue el borde de bosque. Se recolectaron un total de 11808 semillas, siendo Cecropia engleriana la especie más abundante. Los estados sucesionales difieren significativamente en abundancia de semillas, mas no en riqueza; mostrando dominancia de determinados géneros de semillas. Se resalta el arbustal como dinamizador de la sucesión, con un flujo potencial de semillas diversas, donde los murciélagos juegan un papel clave para su dispersión, pues aquellos que vuelan sobre las áreas abiertas tienen la misma carga de semillas para dispersar que los hallados en el bosque, evidenciando un potencial de regeneración coadyuvado por una comunidad de murciélagos con una estructura diversa en grupos tróficos y especies.
Clinical assessment of detection of ventricular extrasystoly in patients without structural changes of heart: a prospective study
Authors: Koziy Anastasia V. , Olesin Alexander I. , Litvinenko Vadim A. , Konstantinova Irina V. 
Published: August 2017

Aim. The aim of the study was a clinical assessment of the integrated determination of predictors of life-threatening ventricular arrhythmias (LVA) in patients with ventricular extrasystole (VE) without structural changes in the heart to predict the development of cardiovascular disease in a prospective study.
Material and methods. From 1997 to 2014 199 patients with neurocirculatory dystonia (NCD), complicated with VE II-V class EE at the age of 18-35 years (mean 27.3-2.6 years) were observed in District Military Clinical Hospital of the Ministry of Defense of the Russian Federation, City Hospital named after St. Martyr Elizabeth. All patients, in addition to a general clinical examination, determined late potentials of the ventricles (LPV), QT interval variability (QTd), heart rate turbulence (HRT), and also indicators reflecting the possible mechanism of VE development.
Results. The results of the study showed that in patients with NCD complicated by VE, the detection of indicators reflecting the presence of VE caused by the mechanisms of early post-depolarization and re-entry is a predictor of the development of coronary heart disease (CHD) and hypertension (HB). The positive prognostic significance of the indicators showing the presence of VE with these development mechanisms for the development of CHD and HB averaged 74% and 44% respectively, and with the appointment of сlass III drugs for elimination of VE and (or) development of unstable ventricular tachycardia, the risk of developing CHD increased to an average of 93%. Identification of NDC patients with indicators reflecting the presence of VE due to delayed post-depolarization is a predictor of the development of gastrointestinal tract (GT) diseases with positive prognostic significance, averaging 61%. Positive prognostic significance with respect to the development of CHD, HB, GT diseases for the detected LPV, QTd > 80 ms, pathological values of HRT VE did not exceed 30%. Indicators and predictors, which characterize the mechanism of development of VE and the risk of LVA occurrence in patients with NCD complicated by VE, were highly correlated (r > 0.50) with risk factors for cardiovascular and gastrointestinal system diseases.
Maternal and fetal outcome in pregnancy with heart disease in tertiary care hospital in India
Authors: Salam Samia , Mushtaq Saba , Mohi-ud-Din Khalid , Gul Irfan , Ali Asifa 
Published: August 2017

Background: Cardiac disease is an important cause of maternal mortality and morbidity both in antepartum and postpartum period. The overall incidence of heart disease in pregnancy is <1%. Objective of present study was to determine maternal outcome in pregnant women with heart diseases in terms of fetal complication, maternal complication and Mode of delivery.Methods: This study was conducted in the Department of Obstetrics and Gynaecology at Government Lalla Ded Hospital, an associated of Government Medical College, Srinagar which is the sole tertiary care referral centre in the valley. 90 women with heart disease which were previously established or diagnosed during pregnancy were enrolled in the study.Results: In 90 women pregnancies was complicated by heart disease in the study. The prevalence of heart disease amongst all pregnancies found in hospital was 4.3%. The principal cause of cardiac lesion was Rheumatic heart disease (RHD) (56.6%) while congenital heart disease was seen in 13.3%. Among the women who had RHD, mitral stenosis seen in 21 (23.3%) was most common lesion and Multiple cardiac lesions 21 (24.4%) women. Among the women with congenital cardiac disease, mitral valve prolapse was most common constituting 5 (5%) cases. Cardiomyopathy was the most common constituting 7 (7.3%). Heart failure developed in 10 (11.1%) whose NYHA class changed from class I/II to class III/IV. Majority of the women delivered by caesarean section 33 (36.7%) while (35.6%) had a normal vaginal delivery with spontaneous onset of labour. 7% had assisted instrumental vaginal delivered. 9% women had first trimester abortion. There were 4 maternal deaths. 85.6% live births were observed in these women. No baby had congenital heart disease. 72.8% babies born weighed more than 2kg.Conclusions: This study concluded that pre- pregnancy diagnosis, counselling, appropriate referral, antenatal supervision and delivery at equipped centre improve the pregnancy with heart disease outcome for both mother and baby.
Abnormal lipid metabolism is associated with angiogenic and anti angiogenic factor imbalance in PIH women
Authors: Jammalamadaga Visala Sree , Abraham Philips 
Published: August 2017

Background: Preeclampsia is a major cause of maternal and fetal/neonatal mortality and morbidity even in developed countries. Despite of extensive research, the etiology and pathogenesis of preeclampsia are not completely understood. Evidence shows that imbalance between angiogenic and antiangiogenic factor plays a pivotal role in the genesis of endothelial dysfunction which is considered as a hall mark in the development of multisystem disorder in pre-eclampsia and eclampsia. Abnormal lipid metabolism is a known causative factor for endothelial dysfunction. This study has been designed to determine the association between abnormal lipids and angiogenic, anti angiogenic balance in PIH (PE and E) women.Methods: Study group consisted of Normotensive pregnant women (N) preeclamptic women (PE) and eclamptic women (E) with 100 subjects in each group in the 3rd trimester of pregnancy. They were investigated for lipid profile and apolipoproteins, MDA, FRAP, TNF-α, sFlt-1, VEGF, PlGF, NO. Statistical analysis was done using ANOVA and pearson correlation analysis.Results: When compared to controls TC, TGL, VLDL, LDL, apoB, MDA, TNF-α, sFlt-1 levels were found to be significantly high and HDL, apoA, FRAP, VEGF, PIGF, and NO levels were significantly low in PE, E group. Eclamptic women showed a significantly high level of MDA, TNF-α, sFlt-1and low levels of FRAP, VEGF, PIGF, NO when compared to PE group.Conclusions: In PIH women, abnormal lipid metabolism is associated with angiogenic and antiangiogenic imbalance.
Meaningful Intervention with Children and Youth: A Reflection on Ten Years of Inquiry
Authors: Artz Sibylle , Nicholson Diana , Halsall Elaine , Larke Susan 
Published: August 2017

<p class="MsoNormal" style="margin: 0in 0in 0pt 28.35pt;"><span style="font-size: small;"><span lang="EN-US">It has been known since the early 1970s that youth risk assessment does not necessarily assist us in determining youth needs and services. Still, where</span><span style="font-family: Times;"><span lang="EN-US"> young people and crime are the concerned, interventions are often focused on risk assessment rather than need assessment, especially when these young people face incarceration. In this article we emphasize needs assessment and the development of a youth friendly approach to such assessment.<span style="mso-spacerun: yes;"> </span>We draw on a number of community-based and community involved studies that were conducted over a ten-year period, studies that </span><span style="mso-ansi-language: EN-GB;" lang="EN-GB">focused on the perspectives, experiences, and needs of children and youth, </span><span lang="EN-US">and present as key among these studies a project on the development of a gender-sensitive tool for needs assessment that can aid workers with youth engagement and needs focused intervention.</span></span></span></p>
Patent Ductus Arteriosus in Preterm Infants, Part 1: Understanding the Pathophysiologic Link Between the Patent Ductus Arteriosus and Clinical Complications
Authors: Elsayed Yasser N. , Fraser Debbie 
Published: August 2017

AbstractThe clinical guidelines for treating patent ductus arteriosus (PDA) have significantly evolved over the last decades from treating any ductal shunt to more conservative management where only the hemodynamically significant patent ductus arteriosus (HSPDA) is treated. This shift has resulted largely from a lack of evidence from randomized controlled trials supporting a relationship between treating a PDA and improving long-term neonatal outcomes. However, there are many unresolved issues. There is no consensus on the precise definition of HSPDA requiring treatment or a clear understanding of when to treat HSPDA. Moreover, the current evidence shows worsening of the long-term neurodevelopmental outcome for infants undergoing surgical PDA ligation.The presence of physiologic variability among preterm infants, and the presence of different compensatory mechanisms may make it difficult to establish a link between pathophysiology and long-term outcomes. That is, the physiologic variability cannot be simply assessed by randomly assigning infants into two arms of a study. Relying on research from animal and human studies, this article explains the link between the pathophysiology of a PDA and neonatal outcomes.
Computer‐Guided Immediate Implant Placement and Predigitally Designed Immediate Provisionalization
Authors: Wang Chin‐Wei (Jeff) , Bhaskar Vaishnavi , Dickerman Brandon , Kaigler Darnell 
Published: August 2017

IntroductionImplementation of digital technology in patient care has allowed precise and personalized implant restorations to be delivered with unprecedented speed. This case report demonstrates that through digital planning, successful guided placement of an immediate implant can be achieved, including bone grafting and immediate provisionalization, using a predesigned and prefabricated restoration.Case PresentationA healthy 38‐year‐old female patient with high esthetic demands presented with an unrestorable maxillary left first premolar. Main challenges in this case included the presence of an impacted adjacent second premolar and the desire of the patient for a fixed provisional prosthesis. The treatment plan involved extraction of the tooth, computer‐guided immediate implant placement, and immediate provisionalization with a digitally designed, presurgically fabricated crown. After immediate delivery of the provisional crown, which facilitated sculpting of the peri‐implant soft tissue, minimal adjustment was required, and there was no need for suturing to seal the grafted socket. After delivery of the final restoration and 10 months of functional loading, evaluation of the implant and restoration revealed stable crestal bone levels with an esthetically pleasing result and high patient satisfaction.ConclusionsDigital technology can play a significant role in implant therapy. Select cases can benefit from the digital workflow to facilitate guided immediate implant placement and delivery of a digitally prefabricated provisional restoration. Further studies are needed to optimize the generalizability of this approach.
Smoking May Lead to Marginal Bone Loss Around Non‐Submerged Implants During Bone Healing by Altering Salivary Microbiome: A Prospective Study
Authors: Duan Xiaobo , Wu Tingxi , Xu Xin , Chen Demeng , Mo Anchun , Lei Yiling , Cheng Lei , Man Yi , Zhou Xuedong , Wang Yongyue , Yuan Quan 
Published: August 2017

Background: This prospective and controlled study elucidates the impact of smoking on the salivary microbiome and its further influence on marginal bone loss (MBL) around an implant during a 3‐month bone‐healing period.Methods: Saliva samples were collected preoperatively from 20 periodontally healthy patients with single‐tooth replacement in the posterior mandible (smokers [n = 10] and non‐smokers [n = 10]). Sequencing of 16S recombinant RNA gene amplicons was used to characterize the salivary microbiome. Each patient received implant surgery after oral clinical assessment, and MBL around the implant was measured during a 3‐month healing period.Results: In total, 871,389 sequences were compared against the Human Oral Microbiome Database for bacterial identification. Microbial signatures of smokers exhibited lower diversity and richness, with a significant decrease in uncultured species. The phyla Gracilibacteria and Saccharibacteria showed a significant decrease in smokers. The genera Streptococcus, Lachnoanaerobaculum, Stomatobaculum, and Eubacterium were significantly increased in smokers, whereas Selenomonas, Selenomonas [G‐3], and Catonella were significantly decreased. Specifically, Porphyromonas gingivalis was significantly more abundant in smokers, which was positively related to the severity of MBL during bone healing.Conclusions: Smoking shapes the salivary microbiome in states of clinical health, and further may influence MBL during bone healing by creating high at‐risk‐for‐harm communities. Understanding of the distinctly divergent oral microbiome in smokers and non‐smokers is a base for personalized therapeutics for this high‐risk cohort and also a base for further study on the pathologic mechanisms.
Evaluation of oxidative status in patients with chronic periodontitis and polycystic ovary syndrome: A cross‐sectional study
Authors: Saglam Ebru , Canakci Cenk Fatih , Sebin Saime Ozbek , Saruhan Nesrin , Ingec Metin , Canakci Hümeyra , Sezer Ufuk 
Published: August 2017

AbstractBackgroundIn patients with polycystic ovary syndrome (PCOS), chronic periodontitis (CP) contributed to increased oxidative stress (OS), owing to an increase in serum and salivary 8‐hydroxy‐2′‐deoxyguanosine (8‐OHdG) and malondialdehyde (MDA) levels and a decrease in serum total antioxidant status (TAS) levels. The aim of the present study is to investigate salivary and serum 8‐OHdG and MDA levels as well as total antioxidant status (TAS) in females with CP and PCOS compared with healthy females.MethodsFour groups, each consisting of 22 individuals, were: 1) women with both PCOS and CP (PCOSCP); 2) systemically healthy women with CP; 3) periodontally healthy women with PCOS (PCOSPH); and 4) periodontally and systemically healthy women (PH). Demographic and clinical periodontal parameters were measured. Oxidative parameters were evaluated in serum and salivary samples.ResultsSalivary 8‐OHdG levels in the PCOSCP and CP groups were statistically higher than those in both the PCOSPH and the PH groups (P < 0.05). There was no statistical difference between the PCOSCP, CP, and PCOSPH groups with regard to salivary MDA and TAS levels (P > 0.05). Highest serum 8‐OHdG and MDA levels and lowest serum TAS levels were seen in the PCOSCP group (P < 0.05). Serum 8‐OHdG and MDA levels in the PCOSPH group were higher than those in both systemically healthy groups (PH and CP) (P < 0.05). Salivary TAS levels were highest (P < 0.05) in the PH group. There was no statistical difference between the CP and PCOSPH groups, but serum TAS levels were lower than those in the PH group (P < 0.05).ConclusionsCP, which led to an increase in serum and salivary 8‐OHdG and MDA levels and a decrease in serum TAS levels in patients with PCOS, contributed to increased OS. This effect was more prominent in serum levels than in salivary levels.
Microbiologic Response to Periodontal Therapy and Multivariable Prediction of Clinical Outcome
Authors: Mombelli Andrea , Almaghlouth Adnan , Cionca Norbert , Cancela José , Courvoisier Delphine S. , Giannopoulou Catherine 
Published: August 2017

Background: This study assesses the microbiologic effects of a two‐phase antimicrobial periodontal therapy and tested microbiologic, clinical, and biologic markers as prognostic indicators for clinical success.Methods: Eighty patients with chronic or aggressive periodontitis received periodontal treatment supplemented with 375 mg amoxicillin plus 500 mg metronidazole, three times daily for 7 days. In group A, antibiotics were given during the first non‐surgical phase (T1); in group B, antibiotics were given during the second surgical phase (T2). Six microorganisms, group assignment, demographic and clinical variables, peak values of 15 cytokines, and nine acute‐phase proteins in serum were evaluated as potential predictors of at least one site with probing depth (PD) >4 mm and bleeding on probing (BOP) at 12 months post‐therapy.Results: T1 decreased the counts of Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia (Pi), and Treponema denticola significantly more in group A than group B. Aggregatibacter actinomycetemcomitans and Parvimonas micra (Pm) showed a significant decrease only if the treatment was supplemented with antibiotics, i.e., T1 in group A, or T2 in group B. After T2, differences between groups were no longer significant. A multivariable model including four parameters revealed a predictive value of Pm (odds ratio [OR] = 4.38, P = 0.02) and Pi (OR = 3.44, P = 0.049) and yielded moderate accuracy for predicting the treatment outcome (area under the curve = 0.72). Host‐derived factors and treatment sequence were not significantly associated with the outcome.Conclusions: Long‐term microbiologic outcomes of periodontal therapy with adjunctive antibiotics either in T1 or T2 were similar. Detection of Pm before therapy was a predictor for persistence of sites with PD >4 mm and BOP at 12 months post‐treatment.
Filme-educação
Authors: Machado Pamela de Bortoli , Akhras Fabio Nauras 
Published: August 2017

O artigo apresenta o chamado Filme-educação que vem com a ideia de "ler" e "escrever" um filme, na medida em que a leitura e escrita são a base de uma compreensão acerca da linguagem cinematográfica. Trata-se de colocar em prática aquilo que foi assimilado e “lido”, a partir de uma produção criativa do próprio aluno, numa imersão de conhecimento que não se dá em uma atividade isolada, ou seja, propicia o estímulo de outras habilidades e conceitos a partir da experiência pelo/ a partir/ com/ o filme. Logo, a partir de tais dizeres, ilustraremos os resultados obtidos com a aplicação de uma oficina embasada pelo conceito de Filme-educação, realizada em escolas da rede municipal de Campinas, São Paulo.
TRABALHO E EDUCAÇÃO NO CONTEXTO DAS POLÍTICAS NEOLIBERAIS:
Authors: Silva Carlos Cardoso , Alves Maria de Lourdes 
Published: August 2017

O objetivo deste texto é suscitar reflexões e análises que podem ser estabelecidas, entre educação e trabalho frente ao modelo neoliberal, desvelando o cotidiano da escola, por meio de pesquisas bibliográficas que discutem essa temática. Os trabalhos pesquisados apontam para: controle, regulação, proletarização docente, desvalorização do trabalho do professor, elementos que não raro têm como consequência o adoecimento docente. Mas a pesquisa bibliográfica, revela um movimento de resistência de professores que não aceitam a mera condição de executores e resistem de modo silencioso a este padrão que pretende moldar o humano. Trata-se de uma revisão bibliográfica, acerca do tema em análise.
Palavras-chave: Trabalho docente. Políticas neoliberais. Adoecimento.
PERAN SERTA ORANG TUA DALAM SISTEM BUDAYA MUTU DI SEKOLAH DASAR PSKD MANDIRI
Authors: RAHAYU DWI 
Published: August 2017

The objective of this research is to gain a deep understanding of the parents involvement in a quality culture system in PSKD MANDIRI Primary School. This research is a case study method. The validity of qualitative data obtained through the extention of time doing research and triangulation of data collection techniques and data sources in the field. The result show: Interpersonal communication in PSKD Mandiri Schools is the result of a good engagement between teachers and parents. Parents understand the procedures how to make a contact with teachers. Parents are also free to choose the communication channel that they desired. Schools encourage the use of technology in the communication between home – school. Several form of written communication have been considered including handbooks, newsletter, progress reports and home – school diaries. Guidelines have been also provided for the use of telephone contacts with parents and for the use of new technological option such as school website, e-mail, ans text messaging. Therefore, it is considered that making a range of strategies available to parents will lead to optional levels of parental involvement in school. However the range of strategies used by the school will mostly be dependent on teachers’s knowledge of and skills for effectively implementing the various strategies. The wide range of activities is also used by school to bring about high levels of parental involvement.