bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parades and Processions
Authors: Ryan Delyse 
Published: August 2016

Parades and processions were a major feature of life in Brisbane during World War I. Parades typically passed through the central business district turning the entire city into an urban backdrop for a public perfonnance. Recruitment was a major issue for Australia during World War I and military parades featured prominently in the life of the city. The Brisbane Courier described the recruiting marches as ‘long columns of robust, khaki-clad manhood’ which ‘have swung down the street, with soldierly gait, setting a bright, sturdy example to shirkers to “go and get their dungarees on”’. By positioning the soldiers as heroic, well-built, and positive, processions helped to generate public enthusiasm for the war and to convince prospective recruits to join up. The message to the community is clear: if our soldiers are fit and spirited, then the Allies will win the war. But the marches were not only a way to rally new recruits, they also acted as public displays of civic solidarity. Parades gave citizens the opportunity to demonstrate their patriotic feelings. ‘Patriotism’, whether for King, country, or for ‘our boys’, was the dominant performative concept. In this way, governments, community organisations, theatrical managements, and the residents themselves contributed to the establishment of certain war-time traditions for the representation of civic patriotism on the streets in Australia.
Palaeobotany of the Bunya Pine
Authors: Hernandez-Castillo Genaro R. , Stockey Ruth A. 
Published: August 2016

The bunya pine (Araucaria bidwillii Hook) is one of the most interesting species of the family Araucariaceae, a typical Southern Hemisphere conifer (Table 1) family that includes three living genera: Araucaria de Jussieu, Agathis Salisbury and the recently described genus Wollemia Jones, Hill and Allen. Araucaria bidwillii is traditionally classified in the Section Bunya of genus Araucaria. In addition to the section Bunya, there are three more sections in the genus Araucaria: Eutacta Endlicher and Intermedia White from Australasia, and Araucaria (=Columbea) Wilde and Eames from South America.
Literary Sidelights on Wartime Brisbane
Authors: Clarke Patricia 
Published: August 2016

There have been several anecdotal accounts of the literary scene in Brisbane during World War II and numerous references in more general works. In 2000, Queensland Review published some reminiscences of writers Estelle Runcie Pinney, Don Munro, Val Vallis and David Rowbotham, under the title ‘Writing in Brisbane during the Second World War’. Some of the more important general works include Judith Wright's ‘Brisbane in Wartime’, Lynne Strahan's history of Meanjin and Judith Armstrong's biographical work on the Christesens, The Christesen Romance. My interest in this subject arose from editing Judith Wright's autobiography, Half a Lifetime, published in 1999, and recently in editing, with her daughter, letters between Judith Wright and Jack McKinney which were mainly written in Brisbane in the later years of the war and the immediate postwar period. Initially my purpose was to gather information to elucidate people or events mentioned in these writings, but my interest widened to embrace more general information about the period. My research led me to the conclusion that Meanjin and its editor Clem Christesen were catalysts for many of the literary activities in Brisbane during World War II, not just among resident Australians, but among troops temporarily stationed in Brisbane — particularly Americans, whom Christesen cultivated and published. This article records a few glimpses of literary life in Brisbane, and incidentally in the rest of the country, during a period described by Patrick Buckridge as never having been researched ‘in enough detail’.
Listening to Noddy
Authors: MacColl Mary-Rose 
Published: August 2016

As a young journalist at the Courier-Mail newspaper, my mother once met the famous British children's writer Enid Blyton, who stopped in Brisbane briefly. There was a press conference in a hangar out at the airport. Many important people were there — the Australian publisher, someone from the British High Commission, someone from the Prime Minister's Office, along with reporters from Sydney and Melbourne — and my mother, my beautiful young mother, in a panama hat with gloves and white glasses, excited to be there, to be amongst it.
'Coppertails and Silvertails'
Authors: Paten Jessica 
Published: August 2016

'Sides have now been taken. The temperance women will have a skirmish of their own for any stray man with no beer stains on his tie, but Miriam's loud timbrel has sounded for the battle royal between Labour and Government women — coppertails and silvertails!'

This call to arms sounded by the Worker towards the close of the campaign for womanhood suffrage in Queensland captured well the class antagonism that prevailed within the movement. At this late stage, there was little chance that the conflicting elements within the movement could put aside their differences and unite in a concerted effort to secure the female franchise. To all intents and purposes, the struggle for womanhood suffrage had become a class war.
The Brisbane Years of Laurence Collinson
Authors: Hatherell William 
Published: August 2016

The autumn 1944 ‘Ern Malley’ edition of Max Harris's Angry Penguins was a defining moment in Australian cultural history for more than one reason. To add to the exposure of the Malley hoax in June 1944, Harris found himself in August having to defend charges of ‘indecent advertisements’ (Heyward, 184). Harris's partner in publishing Angry Penguins, John Reed, wrote in a letter of 5 September 1944 — the day the trial began in the Adelaide Magistrates Court — that the ‘indictment includes 7 of the Malley poems, all of Max's, the Cowan and Stivens stories and Collinson's poem’ (Reed, 367). The 19-year-old Brisbanite Laurence Collinson had conjured up a typically dramatic moment to announce his entry onto the national cultural stage — stumbling into a bit part in a drama that was both a crucial battle in the war between Australian literary modernists and traditionalists, and a worthy local precursor to Britain's Lady Chatterley trial of 1959.
Queensland's Black Leper Colony
Authors: Genever Geoffrey 
Published: August 2016

An increase in the incidence of leprosy among North Queensland Aboriginal people in the late 1930s gave rise to fears that the disease might spread and threaten the white population. This concern resulted in an uninhabited offshore island being selected as a leper colony that was exclusively for blacks: it became a place to which Indigenous people suffering from leprosy were forcibly transported, isolated and treated. Queensland's right to take such action was enshrined in law by the Leprosy Act of 1892 and subsequently by the Public Health Act of 1937 which, while repealing the Leprosy Act, retained the main elements of the earlier legislation.
Tamara Tonite
Authors: Smaal Yorick 
Published: August 2016

In the late 1990s and early 2000s, a locally produced program on community television took the GLBTIQ community by storm. Running for seven years on channel Briz31, Tamara Tonite appeared in, and produced, 365 episodes, interviewing many locally based and national personalities. The success of the show has not been matched by any other privately produced show on community television in Australia. Tamara initially took on the show to promote her own ‘dial a drag queen’ business, but Tamara Tonite took on a form of its own towards the end of 1997. While the show drew a few detractors — with some charismatic church leaders calling her an ‘evil cross-dressing transvestite’ using airwaves to spread her wicked message — Tamara remembers being absolutely floored when she threw the show open to a studio audience one night. Over 60 people turned up, and some had to huddle around TV cameras due to a lack of space.
Total synthesis of teixobactin
Authors: Jin Kang , Sam Iek Hou , Po Kathy Hiu Laam , Lin Du’an , Ghazvini Zadeh Ebrahim H. , Chen Sheng , Yuan Yu , Li Xuechen 
Published: August 2016

AbstractTo cope with the global bacterial multidrug resistance, scientific communities have devoted significant efforts to develop novel antibiotics, particularly those with new modes of actions. Teixobactin, recently isolated from uncultured bacteria, is considered as a promising first-in-class drug candidate for clinical development. Herein, we report its total synthesis by a highly convergent Ser ligation approach and this strategy allows us to prepare several analogues of the natural product.
Quantum electromechanics on silicon nitride nanomembranes
Authors: Fink J. M. , Kalaee M. , Pitanti A. , Norte R. , Heinzle L. , Davanço M. , Srinivasan K. , Painter O. 
Published: August 2016

AbstractRadiation pressure has recently been used to effectively couple the quantum motion of mechanical elements to the fields of optical or microwave light. Integration of all three degrees of freedom—mechanical, optical and microwave—would enable a quantum interconnect between microwave and optical quantum systems. We present a platform based on silicon nitride nanomembranes for integrating superconducting microwave circuits with planar acoustic and optical devices such as phononic and photonic crystals. Using planar capacitors with vacuum gaps of 60 nm and spiral inductor coils of micron pitch we realize microwave resonant circuits with large electromechanical coupling to planar acoustic structures of nanoscale dimensions and femtoFarad motional capacitance. Using this enhanced coupling, we demonstrate microwave backaction cooling of the 4.48 MHz mechanical resonance of a nanobeam to an occupancy as low as 0.32. These results indicate the viability of silicon nitride nanomembranes as an all-in-one substrate for quantum electro-opto-mechanical experiments.
Clinical detection of deletion structural variants in whole-genome sequences
Authors: Noll Aaron C , Miller Neil A , Smith Laurie D , Yoo Byunggil , Fiedler Stephanie , Cooley Linda D , Willig Laurel K , Petrikin Josh E , Cakici Julie , Lesko John , Newton Angela , Detherage Kali , Thiffault Isabelle , Saunders Carol J , Farrow Emily G , Kingsmore Stephen F 
Published: August 2016

AbstractOptimal management of acutely ill infants with monogenetic diseases requires rapid identification of causative haplotypes. Whole-genome sequencing (WGS) has been shown to identify pathogenic nucleotide variants in such infants. Deletion structural variants (DSVs, >50 nt) are implicated in many genetic diseases, and tools have been designed to identify DSVs using short-read WGS. Optimisation and integration of these tools into a WGS pipeline could improve diagnostic sensitivity and specificity of WGS. In addition, it may improve turnaround time when compared with current CNV assays, enhancing utility in acute settings. Here we describe DSV detection methods for use in WGS for rapid diagnosis in acutely ill infants: SKALD (Screening Konsensus and Annotation of Large Deletions) combines calls from two tools (Breakdancer and GenomeStrip) with calibrated filters and clinical interpretation rules. In four WGS runs, the average analytic precision (positive predictive value) of SKALD was 78%, and recall (sensitivity) was 27%, when compared with validated reference DSV calls. When retrospectively applied to a cohort of 36 families with acutely ill infants SKALD identified causative DSVs in two. The first was heterozygous deletion of exons 1–3 ofMMP21 in transwith a heterozygous frame-shift deletion in two siblings with transposition of the great arteries and heterotaxy. In a newborn female with dysmorphic features, ventricular septal defect and persistent pulmonary hypertension, SKALD identified the breakpoints of a heterozygous,de novo1p36.32p36.13 deletion. In summary, consensus DSV calling, implemented in an 8-h computational pipeline with parameterised filtering, has the potential to increase the diagnostic yield of WGS in acutely ill neonates and discover novel disease genes.
A neural substrate for object permanence in monkey inferotemporal cortex
Authors: Puneeth N. C. , Arun S. P. 
Published: August 2016

AbstractWe take it for granted that objects continue to exist after being occluded. This knowledge – known as object permanence – is present even in childhood, but its neural basis is not fully understood. Here, we show that monkey inferior temporal (IT) neurons carry potential signals of object permanence even in animals that received no explicit behavioral training. We compared two conditions with identical visual stimulation: the same object emerged from behind an occluder as expected following its occlusion, or unexpectedly after occlusion of a different object. Some neurons produced a larger (surprise) signal when the object emerged unexpectedly, whereas other neurons produced a larger (match) signal when the object reappeared as expected. Neurons carrying match signals also reinstated selective delay period activity just before the object emerged. Thus, signals related to object permanence are present in IT neurons and may arise through an interplay of memory and match computations.
Preferential Nucleation during Polymorphic Transformations
Authors: Sharma H. , Sietsma J. , Offerman S. E. 
Published: August 2016

AbstractPolymorphism is the ability of a solid material to exist in more than one phase or crystal structure. Polymorphism may occur in metals, alloys, ceramics, minerals, polymers, and pharmaceutical substances. Unresolved are the conditions for preferential nucleation during polymorphic transformations in which structural relationships or special crystallographic orientation relationships (OR’s) form between the nucleus and surrounding matrix grains. We measured in-situ and simultaneously the nucleation rates of grains that have zero, one, two, three and four special OR’s with the surrounding parent grains. These experiments show a trend in which the activation energy for nucleation becomes smaller – and therefore nucleation more probable - with increasing number of special OR’s. These insights contribute to steering the processing of polymorphic materials with tailored properties, since preferential nucleation affects which crystal structure forms, the average grain size and texture of the material, and thereby - to a large extent - the final properties of the material.
Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein
Authors: Coscia Francesca , Estrozi Leandro F. , Hans Fabienne , Malet Hélène , Noirclerc-Savoye Marjolaine , Schoehn Guy , Petosa Carlo 
Published: August 2016

AbstractRecent technical advances have revolutionized the field of cryo-electron microscopy (cryo-EM). However, most monomeric proteins remain too small (<100 kDa) for cryo-EM analysis. To overcome this limitation, we explored a strategy whereby a monomeric target protein is genetically fused to a homo-oligomeric scaffold protein and the junction optimized to allow the target to adopt the scaffold symmetry, thereby generating a chimeric particle suitable for cryo-EM. To demonstrate the concept, we fused maltose-binding protein (MBP), a 40 kDa monomer, to glutamine synthetase, a dodecamer formed by two hexameric rings. Chimeric constructs with different junction lengths were screened by biophysical analysis and negative-stain EM. The optimal construct yielded a cryo-EM reconstruction that revealed the MBP structure at sub-nanometre resolution. These findings illustrate the feasibility of using homo-oligomeric scaffolds to enable cryo-EM analysis of monomeric proteins, paving the way for applying this strategy to challenging structures resistant to crystallographic and NMR analysis.
Association between bilirubin and risk of Non-Alcoholic Fatty Liver Disease based on a prospective cohort study
Authors: Tian Jianbo , Zhong Rong , Liu Cheng , Tang Yuhan , Gong Jing , Chang Jiang , Lou Jiao , Ke Juntao , Li Jiaoyuan , Zhang Yi , Yang Yang , Zhu Ying , Gong Yajie , Xu Yanyan , Liu Peiyi , Yu Xiao , Xiao Lin , Du Min , Yang Ling , Yuan Jing , Wang Youjie , Chen Weihong , Wei Sheng , Liang Yuan , Zhang Xiaomin , He Meian , Wu Tangchun , Yao Ping , Miao Xiaoping 
Published: August 2016

AbstractThe study aimed to assess the association between total, direct and indirect bilirubin and nonalcoholic fatty live disease (NAFLD) risk given its high prevalence and serious clinical prognosis. Among 27,009 subjects who participated in a healthy screening program from the Dongfeng-Tongji cohort study in 2008, 8189 eligible subjects (aged 35–86 years; males, 43.95%) were ultimately enrolled. The incidence rates of NAFLD in 2013 were compared with respect to baseline bilirubin levels among subjects free of NAFLD and the effect sizes were estimated by logistic regression analysis. During 5 years follow-up, we observed 1956 cases of newly developed NAFLD with the overall incidence of 23.88%. Direct bilirubin was presented to inversely associate with NAFLD risk. Compared with quartile 1 of direct bilirubin, the multivariable-adjusted ORs (95% CIs) for NAFLD of quartile 2 to 4 were 1.104 (0.867–1.187), 0.843 (0.719–0.989) and 0.768 (0.652–0.905), respectively, P for trend 0.002). Similarly, inverse effects of direct bilirubin on NAFLD incidence were also observed when stratified by sex and BMI. However, no significant associations were found between total and indirect bilirubin and NAFLD risk. Direct bilirubin reduced NAFLD risk independent of possible confounders among middle-aged and elderly Chinese population, probably based on the endogenous antioxidation of bilirubin.
Effect of gear ratio on peak power and time to peak power in BMX cyclists
Authors: Rylands Lee P. , Roberts Simon J. , Hurst Howard T. 
Published: August 2016

AbstractThe aim of this study was to ascertain if gear ratio selection would have an effect on peak power and time to peak power production in elite Bicycle Motocross (BMX) cyclists. Eight male elite BMX riders volunteered for the study. Each rider performed three, 10‐s maximal sprints on an Olympic standard indoor BMX track. The riders’ bicycles were fitted with a portable SRM power meter. Each rider performed the three sprints using gear ratios of 41/16, 43/16 and 45/16 tooth. The results from the 41/16 and 45/16 gear ratios were compared to the current standard 43/16 gear ratio. Statistically, significant differences were found between the gear ratios for peak power (F(2,14) = 6.448; p = .010) and peak torque (F(2,14) = 4.777; p = .026), but no significant difference was found for time to peak power (F(2,14) = 0.200; p = .821). When comparing gear ratios, the results showed a 45/16 gear ratio elicited the highest peak power,1658 ± 221 W, compared to 1436 ± 129 W and 1380 ± 56 W, for the 43/16 and 41/16 ratios, respectively. The time to peak power showed a 41/16 tooth gear ratio attained peak power in −0.01 s and a 45/16 in 0.22 s compared to the 43/16. The findings of this study suggest that gear ratio choice has a significant effect on peak power production, though time to peak power output is not significantly affected. Therefore, selecting a higher gear ratio results in riders attaining higher power outputs without reducing their start time.
NRGC: a novel referential genome compression algorithm
Authors: Saha Subrata , Rajasekaran Sanguthevar 
Published: August 2016

Motivation: Next-generation sequencing techniques produce millions to billions of short reads. The procedure is not only very cost effective but also can be done in laboratory environment. The state-of-the-art sequence assemblers then construct the whole genomic sequence from these reads. Current cutting edge computing technology makes it possible to build genomic sequences from the billions of reads within a minimal cost and time. As a consequence, we see an explosion of biological sequences in recent times. In turn, the cost of storing the sequences in physical memory or transmitting them over the internet is becoming a major bottleneck for research and future medical applications. Data compression techniques are one of the most important remedies in this context. We are in need of suitable data compression algorithms that can exploit the inherent structure of biological sequences. Although standard data compression algorithms are prevalent, they are not suitable to compress biological sequencing data effectively. In this article, we propose a novel referential genome compression algorithm (NRGC) to effectively and efficiently compress the genomic sequences.
Results: We have done rigorous experiments to evaluate NRGC by taking a set of real human genomes. The simulation results show that our algorithm is indeed an effective genome compression algorithm that performs better than the best-known algorithms in most of the cases. Compression and decompression times are also very impressive.
Availability and Implementation: The implementations are freely available for non-commercial purposes. They can be downloaded from: http://www.engr.uconn.edu/~rajasek/NRGC.zip
Contact: rajasek@engr.uconn.edu
ROSE: a deep learning based framework for predicting ribosome stalling
Authors: Zhang Sai , Hu Hailin , Zhou Jingtian , He Xuan , Jiang Tao , Zeng Jianyang 
Published: August 2016

AbstractWe present a deep learning based framework, called ROSE, to accurately predict ribosome stalling events in translation elongation from coding sequences based on high-throughput ribosome profiling data. Our validation results demonstrate the superior performance of ROSE over conventional prediction models. ROSE provides an effective index to estimate the likelihood of translational pausing at codon resolution and understand diverse putative regulatory factors of ribosome stalling. Also, the ribosome stalling landscape computed by ROSE can recover the functional interplay between ribosome stalling and cotranslational events in protein biogenesis, including protein targeting by the signal recognition particle (SRP) and protein secondary structure formation.
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
Authors: Gusev Alexander , Mancuso Nick , Finucane Hilary K , Reshef Yakir , Song Lingyun , Safi Alexias , Oh Edwin ,   Schizophrenia Working Group of the Psychiatric Genomics Consortium, McCarroll Steven , Neale Benjamin , Ophoff Roel , O’Donovan Michael C , Katsanis Nicholas , Crawford Gregory E , Sullivan Patrick F , Pasaniuc Bogdan , Price Alkes L 
Published: August 2016

ABSTRACTGenome-wide association studies (GWAS) have identified over 100 risk loci for schizophrenia, but the causal mechanisms remain largely unknown. We performed a transcriptome-wide association study (TWAS) integrating expression data from brain, blood, and adipose tissues across 3,693 individuals with schizophrenia GWAS of 79,845 individuals from the Psychiatric Genomics Consortium. We identified 157 genes with a transcriptome-wide significant association, of which 35 did not overlap a known GWAS locus; the largest number involved alternative splicing in brain. 42/157 genes were also associated to specific chromatin phenotypes measured in 121 independent samples (a 4-fold enrichment over background genes). This high-throughput connection of GWAS findings to specific genes, tissues, and regulatory mechanisms is an essential step toward understanding the biology of schizophrenia and moving towards therapeutic interventions.