bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recurrent Cerebral Astroblastoma with Aggressive Histology: An Uncommon Case
Authors: Bansal Sumit , Patra Susama , Mishra Pritinanda , Mahapatra Ashok 
Published: April 2017

AbstractAstroblastomas are uncommon tumors of uncertain histogenesis. Recently tanycyte is postulated to be the cell of origin. These occur predominantly in the cerebral hemisphere of young adults and children. Astroblastoma constitutes approximately 0.45 to 2.8% of all neuroglial tumors. We are reporting a case of 28-year-old woman who presented with headache and double vision. Magnetic resonance imaging (MRI) of the brain revealed well-demarcated, ring-enhancing solid cystic mass in right temporoparietal lobe with significant mass effect. The patient underwent gross total resection of the lesion through right temporoparietal craniotomy. The histopathologic diagnosis was suggestive of astroblastoma. She was advised for postoperative radiotherapy, but she lost to follow-up and again presented 1 year later with recurrent tumor in the same location along with another lesion in infratentorial location. She was reoperated and gross total excision of supra- and infratentorial tumor was done. She also received radiotherapy. We are reporting this uncommon case of astroblastoma and also reviewing the existing literature.
Education in the Waiting Room
Authors: Reid Sarah , Neto Gina , Tse Sandy , Farion Ken J. , Marvizi Ariyan , Smith Lauren , Clarkin Chantalle , Rohde Kristina , Moreau Katherine 
Published: April 2017

Objective
The aim of this study was to understand parents’ awareness of and reactions to a slide presentation based waiting-room educational initiative.

Methods
This was a prospective observational study at a Canadian tertiary-care pediatric emergency department (ED) with an annual census of 68,000 visits. An anonymous parental survey was developed de novo, and parents were asked to complete the survey during their low-acuity ED visit over a 2-week study period. Descriptive statistics were used to describe responses and themes.

Results
Parents completed 520 surveys (733 approached, 70.9% response rate). Eighty-three percent of respondents had previously sought care in the ED. Most parents (68.9%) were aware of the slide presentation, but only 33.7% were able to watch it in its entirety (20 minutes’ duration). Of those who watched the whole presentation, 62.9% understood that lower-acuity cases are assessed in the ambulatory zone of the ED, and sicker children are assessed in the acute zone (89.4%), 79.9% felt the presentation helped them to understand how the ambulatory zone functions, and 83.2% appreciated the current wait-time information. General questions about common health concerns were answered correctly in 58.3% (fever), 56.0% (gastroenteritis), 50.5% (abdominal pain/constipation), 35.7% (earache), and 17.0% (head injury).

Conclusions
The majority of parents were aware of this waiting-room educational initiative, but there was variable uptake of information. Parents watching the entire presentation appreciated the information provided, especially wait-time information, and felt it improved their experience. Knowledge of common health conditions was low; novel methods of knowledge transfer must be utilized and evaluated.
Evaluating the relationship between social exclusion and participation in the informal sector in the European Union
Authors: Williams Colin C. , Horodnic Ioana A. 
Published: April 2017

Purpose
The purpose of this paper is to evaluate who engages in informal work. The intention in doing so is to analyse whether important causal factors of social exclusion such as age, education, gender and employment status influence participation in informal work in the European Union.

Design/methodology/approach
To do this, a 2013 Eurobarometer survey of who participates in undeclared work in 28 European member states is reported.

Findings
Using multilevel mixed-effects logistic regression analysis, the finding is that although some marginalised groups (the unemployed, those having difficulties paying their household bills, the working class and younger age groups) are significantly more likely to participate in the informal sector, others are not (those with less formal education and living in rural areas) and yet others (women and people in deprived European regions) are significantly less likely to participate.

Research limitations/implications
The outcome is a call for a nuanced and variegated understanding of the relationship between participation in the informal sector and social exclusion.

Practical implications
These results display the specific populations that need targeting when seeking to tackle informal work, revealing for example that the current the allocation of European funds for tackling informal work in poorer EU regions is mistaken, but that the targeting of the unemployed is not and current policy initiatives such as smoothing the transition from unemployment to self-employment worthwhile.

Originality/value
This is the first extensive evaluation of the relationship between participation in the informal sector and social exclusion at the level of the European Union
The effects of (different types of) immigrants on labor market outcomes of (different groups of) natives
Authors: Asali Muhammad 
Published: April 2017

Purpose
The purpose of this paper is to study the effects of different types of immigrants on the labor market outcomes of different native groups.

Design/methodology/approach
The study uses a quasi-experimental approach, utilizing the border closures policy as well as political instability and economic conditions in the major countries of origin as exogenous sources of variation in the number of immigrants, to measure the effect of an immigrant-induced labor supply shock of each immigrant type (Palestinians and foreign guest workers) on the wage and employment of native workers (Israeli Arabs and Israeli Jews).

Findings
The effects of immigrants on local labor market outcomes vary with their origin. The different native groups, moreover, are affected differently by each type of immigrants. Specifically, a foreign-worker-induced increase in the labor supply negatively affects only the least-skilled Jewish workers. In contrast, a 10 percent Palestinian-induced increase in the labor supply increases the wage of Israeli Arabs by 3.4 percent, suggesting a net complementarity effect. Short-term slight employment adjustments occur at the intensive rather than the extensive margin.

Originality/value
The paper studies heterogeneous effects of immigrants by their type; also it studies heterogeneous effects experienced by different native groups. This paper informs the policy discussion about immigration and its effects on native workers.
Gender wage gap and education: a stochastic frontier approach
Authors: Garcia-Prieto Carmen , Gómez-Costilla Patricia 
Published: April 2017

PurposeThe purpose of this paper is to get deeper insight into the measurement of gender wage gap. A proper method to identify which part of gender wage differences is due to discrimination against women is provided, and the relationship between wage differences and education is studied.Design/methodology/approachThe stochastic frontier approach is employed to measure wage discrimination against women by using Spanish data from the European Union Statistics on Income and Living Conditions. Mentioned technique allows the authors to split the gender wage gap of workers displaying the same characteristics into two components: the first measures inefficiency in the job search process caused by imperfect information or gender differences concerning preferences regarding working conditions, where as the second takes account of discrimination.FindingsA significant level of discrimination is found in the Spanish labour market at all educational levels, but this problem is quantitatively more important when low-educated workers are studied, and gender discrimination is lower for highly educated women.Originality/valueIn this paper, workers’ potential wage is estimated, and gender discrimination is measured by the gender potential wage gap, since it is not dependent on other wage determinants such as diverse preferences, unmeasured working abilities or imperfect information.
Linking relationship marketing to social embeddedness in a rural bilingual context
Authors: Parry Sara , Westhead Paul 
Published: April 2017

Purpose
The purpose of this paper is to explore the evolution of relationship marketing (RM) in a new technology-based firm (NTBF) and to illustrate how social embeddednesss benefits can be achieved by engaging in RM in a rural resource-constrained bilingual context.

Design/methodology/approach
A single in-depth case study of a NTBF operating in a rural bilingual context was explored over a five-year period. As part of the case study, participant observation was carried out and interviews with the novice entrepreneur, the firm’s employees and its customers were conducted.

Findings
Developing mutually beneficial relationships with customers and key partners can enable a novice entrepreneur with no prior business ownership and limited marketing experience to accumulate and mobilise resources in order to achieve credibility and business growth. By analysing information from the NTBF’s entrepreneur, customers and other actors, the authors build theory and present propositions relating to the RM process.

Practical implications
This case illustrates that RM can enhance the legitimacy of an inexperienced entrepreneur, and can enable a firm to address the liabilities of newness in a rural resource-constrained context. Entrepreneurs need to focus on relevant and specialised partnership and alliance relationships that can provide strategic resources for firm development. The bilingual influence has also been shown to aid the development of new relationships and thus ensuring social embeddedness.

Originality/value
The theoretical contribution of this study is to integrate insights from both RM and social embeddedness theories, and illustrate the extent to which a NTBF demonstrates social embeddedness benefits relating to customer retention and accumulation of strategic resources due to RM.
Cu/SnAgCu/Cu TLP with different thicknesses for 3D IC
Authors: Zhang Liang , Liu Zhi-quan , Yang Fan , Zhong Su-juan 
Published: April 2017

PurposeThis paper aims to investigate Cu/SnAgCu/Cu transient liquid phase (TLP) bonding with different thicknesses for three-dimensional (3D) integrated circuit (IC).Design/methodology/approachThis paper includes experiments and finite element simulation.FindingsThe growth rate of the intermetallic compound layer during TLP soldering was calculated to be 0.6 μm/s, and the small scallop-type morphology Cu6Sn5grains can be observed. With the decrease in thickness in solder joint, the thickness of intermetallic compounds represents the same size and morphology, but the size of eutectic particles (Ag3Sn, Cu6Sn5) in the matrix microstructure decrease obviously. It is found that with the increase in thickness, the tensile strength drops obviously. Based on finite element simulation, the smaller value of von Mises demonstrated that the more reliability of lead-free solder joints in 3D IC.Originality/valueThe Cu/SnAgCu/CuTLPbondingwithdifferentthicknessesfor3D IC was investigated.
Measurement Issues: The measurement of obsessive compulsive disorder in children and young people in clinical practice
Authors: Bennett Sophie D. , Coughtrey Anna E. , Shafran Roz , Heyman Isobel 
Published: April 2017

BackgroundIf left untreated, obsessive compulsive disorder (OCD) can cause significant distress and impact on functioning throughout the lifespan. Despite the severity of the disorder, there is often a significant delay between the onset of symptoms and successful treatment. This is in part due to delays in recognising OCD symptoms in young people, particularly if the symptom forms are less common. Once OCD is accurately diagnosed, cognitive behavioural therapy (CBT) is known to be an efficacious treatment, sometimes in combination with medication, producing good long‐term prognosis. It is therefore important to accurately detect OCD in children and young people so that they can be offered timely intervention. Use of the best tools in clinical and research settings improves detection and diagnosis, as well as enabling the tracking of progress through treatment. The aim of this current paper was to review measurement tools for OCD in young people with a focus on the practicalities of using tools in busy child mental health clinical settings.MethodTo discover what measurement tools are available for OCD in young people, we conducted a pragmatic literature of measurement tools for OCD in young people. We searched PsycINFO, Med‐Line and the Cochrane databases for reports relating to the measurement of OCD. Additionally, we sought information from the National Institute for Health and Care Excellence (NICE) guidance, the Child Outcomes Research Consortium (CORC) website and the Children and Young People's Improving Access to Psychological Therapies (CYP IAPT) Programme. We also reviewed large trials and meta‐analyses of the treatment of OCD in young people and communicated with relevant researchers/clinicians.ResultsSeventeen questionnaire measurement tools, with variable psychometric properties, and four commonly used semistructured clinician administered interview measures were identified.ConclusionsThere are several measurement tools with good psychometric properties that are useful for initial screening/identification of OCD, as well as formal diagnosis, symptom tracking and treatment evaluation. With the availability of brief screens, as well as online diagnostic measures, such tools should not be a burden on clinical practice, but rather a helpful aid to support clinicians' assessment and treatment of OCD.
Editorial: Pharmacotherapy and adolescent depression – an important treatment option
Authors: Dubicka Bernadka , Brent David 
Published: April 2017

Over the past decade, rates of depression and of suicide in adolescents have been increasing (Collishaw, Journal of Child Psychology and Psychiatry, 56, 2015, 370; Bor et al., The Australian and New Zealand Journal of Psychiatry, 48, 2014, 606). At the same time, there is some evidence that rates of diagnosis and, in the US at least, referral for depression in adolescents has been declining (Libby et al., Archives of General Psychiatry, 66, 2009, 633; John et al., Psychological Medicine, 46, 2016, 3315). These worrying statistics highlight the importance of disseminating accurate information about the risks and benefits of treatments for adolescent depression, in order to combat therapeutic nihilism. Extant controversy about the best ways to treat adolescent depression, and in particular with regards to the use of antidepressants, may have contributed to these trends. More specifically, we believe that some recent, high profile publications have incorrectly interpreted the benefit to risk ratio for the use of antidepressants in adolescent depression as unfavourable (e.g. Cipriani et al., The Lancet, 388, 2016, 881). In this editorial, we review clinical trial and pharmaco‐epidemiological data that supports the retention of the use of antidepressants in the management of depressed adolescents.
Validation of PAGE‐B model in Asian chronic hepatitis B patients receiving entecavir or tenofovir
Authors: Kim Mi Na , Hwang Seong Gyu , Rim Kyu Sung , Kim Beom Kyung , Park Jun Yong , Kim Do Young , Ahn Sang Hoon , Han Kwang‐Hyub , Kim Seung Up 
Published: April 2017

AbstractBackground & AimsA new hepatocellular carcinoma risk prediction model, PAGE‐B, which includes age, gender and platelet count as constituent variables, has recently been proposed in Caucasian chronic hepatitis B patients. We validated PAGE‐B model and compared its accuracy with that of conventional risk prediction models in Asian chronic hepatitis B patients.MethodsChronic hepatitis B patients treated with entecavir or tenofovir were consecutively recruited. The performance of PAGE‐B and three conventional risk prediction models (CU‐HCC, GAG‐HCC and REACH‐B) were analysed.ResultsA total of 1092 chronic hepatitis B patients (668 men, 61.2%) were selected between August 2006 and January 2015. The mean age was 48 years. During the follow‐up period (median, 43.6 months), 36 (3.3%) patients developed hepatocellular carcinoma. Older age (hazard ratio [HR]=1.077), male gender (HR=3.676) and lower platelet count (HR=0.984) were independent predictors of hepatocellular carcinoma development. The PAGE‐B showed similar area under receiver operating characteristic curves (AUROCs) to GAG‐HCC and CU‐HCC at 3 years (0.777 vs 0.793 and 0.743, respectively; all P>.05) and 5 years (0.799 vs 0.803 and 0.744, respectively; all P>.05), whereas the AUROCs of PAGE‐B were significantly higher than those of the REACH‐B (0.602 at 3 years and 0.572 at 5 years, P<.05).ConclusionsOur study demonstrated that PAGE‐B is applicable to Asian chronic hepatitis B patients receiving ETV or TDF therapy. The PAGE‐B showed similar predictive performance to GAG‐HCC and CU‐HCC.
3D gravimetric investigation of the Cerro do Jarau structure, Rio Grande do Sul, Brazil
Authors: Giacomini Bruno B. , Leite Emilson P. , Crósta Alvaro P. 
Published: April 2017

AbstractThe Cerro do Jarau structure is possibly the third Brazilian basaltic crater formed in continental flood basalt of the Serra Geral Formation, Paraná Basin, a large igneous province (LIP) in southern Brazil. It is a nearly circular landform with a diameter of approximately 13 km that rises 200 m above the plains of the “pampas” in southern Brazil. In this work, Bouguer anomalies were calculated from gravity accelerations measured on the area of this structure. The residual Bouguer map shows a strong positive anomaly trending NE‐SW, located in the northeastern part of the structure, a feature not commonly associated with impact structures. However, the negative anomaly present in its center and the circular positive anomaly surrounding the central portion are typical of impact structures. The residual Bouguer anomaly varies from −2 mGal to 8 mGal. The positive circular anomaly is not spatially coincident with the rim of the structure. Based on the interpretation of our gravimetric data, the estimated diameter of the structure is 12 km and the central portion has a diameter of approximately 5 km, both slightly smaller than previously suggested. The Bouguer anomaly map was inverted into a 3D density model using a constrained inversion method with a maximum density contrast of 0.5 g cm−3. This model was interpreted to associate densities with rock types, resulting in a geological model. This geological model is in accordance with the meteorite impact nature of Cerro do Jarau.
The promise of transferable fishing concessions on EU fisheries
Authors: Kanik Zafer , Kucuksenel Serkan 
Published: April 2017

AbstractTwo of the main proposals for the reform of the European Union (EU) Common Fisheries Policy (CFP) in 2011 were related to maximum sustainable yield (MSY) and transferable fishing concessions (TFCs). The European Commission (EC) proposed the goal of achieving MSY for all European fisheries. The EC also proposed implementation of TFCs under some major principles including reserving a part of total quotas for small‐scale fishermen in order to prevent the disappearance of small‐scale fishing communities in coastal regions. Even though TFCs have not been a major part of the last reform in 2013, we theoretically study what the potential effects of TFCs would be on the achievement process of MSY harvesting conditions under the major principles defined by the EC. We find that the level of reserved quotas for small‐scale fishermen does matter since reserving more quotas for small‐scale fishermen, using more selective fishing techniques than large‐scale fishermen, reduces the time needed to achieve MSY.
In Vivo
Efficacy of Liposomal Amphotericin B against Wild-Type and Azole-Resistant Aspergillus fumigatus Isolates in Two Different Immunosuppression Models of Invasive Aspergillosis
Authors: Seyedmousavi Seyedmojtaba , Mouton Johan W. , Melchers Willem J. G. , Verweij Paul E. 
Published: April 2017

ABSTRACT

Using an immunocompetent murine model of invasive aspergillosis (IA), we previously reported that the efficacy of liposomal amphotericin B (L-AmB) (Ambisome) is not hampered by the presence of azole resistance mutations in
Aspergillus fumigatus
(S. Seyedmousavi, W. J. G. Melchers, J. W. Mouton, and P. E. Verweij, Antimicrob Agents Chemother 57:1866–1871, 2013,
https://doi.org/10.1128/AAC.02226-12
). We here investigated the role of immune suppression, i.e., neutropenia and steroid treatment, in L-AmB efficacy in mice infected with wild-type (WT)
A. fumigatus
and with azole-resistant
A. fumigatus
harboring a TR
34
/L98H mutation in the
cyp-51A
gene. Survival of treated animals at day 14 in both immunosuppressed models was significantly better than that of nontreated controls. A dose-response relationship was observed that was independent of the azole-resistant mechanism and the immunosuppression method used. In the neutropenic model, 100% survival was reached at an L-AmB dose of 16 mg/kg of body weight for the WT strain and the TR
34
/L98H isolate. In the steroid-treated group, 90.9% survival and 100% survival were achieved for the WT isolate and the TR
34
/L98H isolate with an L-AmB dose of 16 mg/kg, respectively. The 50% effective dose (ED
50
) was 1.40 mg/kg (95% confidence interval [CI], 0.66 to 3.00 mg/kg) for the WT isolate and 1.92 mg/kg (95% CI, 0.60 to 6.17 mg/kg) for the TR
34
/L98H isolate in the neutropenic model and was 2.40 mg/kg (95% CI, 1.93 to 2.97 mg/kg) for the WT isolate and 2.56 mg/kg (95% CI, 1.43 to 4.56 mg/kg) for the TR
34
/L98H isolate in the steroid-treated group. Overall, there were no significant differences between the two different immunosuppressed conditions in the efficacy of L-AmB against the wild-type and azole-resistant isolates (
P
> 0.9). However, the required L-AmB exposure was significantly higher than that seen in the immunocompetent model.
A new species of Phrynus Lamarck, 1801 (Arachnida: Amblypygi), from Trinidad and Tobago, and Venezuela, with a redescription of Phrynus pulchripes (Pocock, 1894)
Authors: JOYA DANIEL CHIRIVI 
Published: April 2017

We present the description of Phrynus calypso sp. nov. from Trinidad and Tobago, and Venezuela This species is very similar to Phrynus pulchripes (Pocock), however after examining Colombian specimens of P. pulchripes (ca. type locality), many differences were found. Characters commonly used in diagnosis of Phrynus species are variable and make identification difficult. Differences in a few structures, like pedipalpal spines, could not be enough to provide a useful diagnosis. It is necessary to account for variation of similar species in conjunction, and select non overlapping groups of characters. Observations in the variation in both species are presented, pointing out sources of confusion, and suggesting alternative characters to support diagnoses. At the moment, details about variation in many species in Phrynus, like that of P. pulchripes, are poorly known, and for this reason a redescription is provided.