bluuebunny/crossref_metadata_2025_split huggingface dataset:
El evidencial con humor entra. Acerca de su uso en los monólogos humorísticos
Authors: Ruiz Gurillo Leonor 
Published: January 2018

Este artículo analiza la función de los evidenciales en los monólogos humorísticos y, más concretamente, en los de Andreu Buenafuente producidos entre 2007 y 2011 (203 monólogos). Partiendo de una concepción funcional y semántica de la evidencialidad, se proponen las siguientes hipótesis: el género determina las funciones pragmáticas de la evidencialidad; los evidenciales se integran en la estructura expositiva-argumentativa del monólogo; teniendo en cuenta su papel estructural, se pueden distinguir diversas estrategias de evidencialidad: y los evidenciales actúan como marcas humorísticas. Se presenta un análisis tanto cuantitativo como cualitativo de los elementos según, según dicen, dicen que, se ve que y claro. Asimismo, se propone un marco semántico-pragmático de los evidenciales y la evidencialidad en los monólogos humorísticos de Buenafuente.
Una aproximación a la atenuación y sus recursos en el discurso de políticos mexicanos Those who say that yes without saying yes. An approach to the mitigation and its resources in the discourse of Mexican politicians
Authors: Infante Bonfiglio Jose María , Flores Treviño Maria Eugenia 
Published: January 2018

Resumen:
Las leyes y reglamentos electorales mexicanos contienen una extraña y curiosa disposición: nadie puede proclamarse o presentarse como candidato antes de los plazos especificados, que tienen como fecha de inicio los que las instituciones encargadas de organizar las elecciones establecen como comienzo de las campañas electorales. El proceso incluye la selección de los candidatos por los partidos reconocidos legalmente (o los procesos de selección de candidatos independientes).
Antes de esa fecha, quien diga que será candidato, está expuesto a que se le niegue el registro y con ello la posibilidad de presentarse a elección. En este trabajo analizamos el discurso en las diversas respuestas dadas por los virtuales candidatos a las demandas expresas de personas, medios de comunicación u otras instituciones sobre si serán candidatos. El periodo revisado corresponde a las elecciones efectuadas en el estado de Nuevo León, México, en junio de 2015.
Coincidimos con Albelda (2005), en que es necesario distinguir atenuación de cortesía, pero proponemos que también hay que deslindar atenuación de negación, ambigüedad o vaguedad. En el análisis de los ejemplos para los casos mencionados creemos que debemos proporcionar una aproximación pertinente para referirnos a este tipo de actos ilocutivos (Van Eemeren y Grootendorst, 2013) que aparecen matizados por estos fenómenos.
Palabras clave: atenuación, negación, ambigüedad, vaguedad.

Abstract
Mexican electoral laws and regulations contain a strange and curious disposition: no one can be proclaimed or presented as a candidate before the specified deadlines, whose date are those that the institutions in charge of organizing the elections established at the beginning of the electoral campaigns. The process includes the selection of candidates by legally recognized parties (or processes for selecting independent candidates).
Before the stipulated date, whoever says that will be a candidate, is exposed to the denial of registration and thus the possibility of appearing in the election. In this paper we analyze the discourse in a variety of answers given by the virtual candidates to the expressed demands of people, the media or other institutions on whether they will be candidates. The period studied corresponds to the elections held in the State of Nuevo Leon, Mexico, in June 2015.
We agree with Albelda (2005) in which it is necessary to distinguish atenuation from courtesy, but we propose that also have to delimit the attenuation of denial, ambiguity or vagueness. In the analysis of the examples for the cases mentioned, we believe that we must provide an appropiate approach to refer to this type of illocutionary acts (van Eemeren & Grootendorst, 2013) that are delimited by these phenomena.
Keywords: attenuation, negation, ambiguity, vagueness.
A Polymer Film with Very High Seebeck Coefficient and Overall Thermoelectric Properties by Secondary Doping, Dedoping Engineering and Ionic Energy Filtering
Authors: Du Minzhi , Wen Yue , Chen Zhijun , Xu Yichen , Qin Jie , Cheng Hanlin , Du Yong , Zhang Kun , Shin Sunmi , Ouyang Jianyong 
Published: October 2024

AbstractThermoelectric (TE) materials are significant for sustainable development because they can be used to harvest waste heat into electricity. Organic TE materials have unique merits including high mechanical flexibility, low cost, and low intrinsic thermal conductivity. But their TE properties particularly the Seebeck coefficient are notably lower than the inorganic counterparts. Here, a poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) film is reported with a very high Seebeck coefficient and figure of merit (zT) at room temperature through secondary doping, dedoping engineering, and ionic energy filtering. The PEDOT:PSS films are successively treated with acid, base, and vitamin C that is a reductant, and then coated with 1‐ethyl‐3‐methylimidazolium dicyanamide (EMIM:DCA) that is an ionic liquid. This can exhibit a record‐high Seebeck coefficient and power factor of 111 µV K−1 and 1285 µW m−1 K−2, respectively, and the corresponding zT value is 1.05. This is the highest zT value for polymers and polymer composites, and it is comparable to that of the best inorganic TE materials.
Fiber‐Dependent 3D Anisotropic Stiffness‐Tunable Biomimetic Intervertebral Disc via Multi‐Material Additive Manufacturing
Authors: Fan Weiguo , Qian Zhihui , Song Guangsheng , Wang Kunyang , Galbusera Fabio , Ren Lei , Wilke Hans‐Joachim , Ren Luquan 
Published: October 2024

AbstractLumbar intervertebral disc degeneration is a global musculoskeletal disorder. Total disc replacement is an effective treatment for symptomatic degeneration unresponsive to conservative care. However, current artificial discs, with their joint‐like structural design and homogeneous materials, fail to replicate the 3D anisotropic stiffness of natural discs. Inspired by the intricate structure and material gradient of the natural disc, a biomimetic intervertebral disc is designed and fabricated using multi‐material additive manufacturing. The biomimetic disc exhibits 3D anisotropic stiffness similar to natural discs. By adjusting the hardness, diameter, and arrangement of fibers in annulus fibrosus, the biomimetic disc closely matches the 3D anisotropic stiffness of the natural lumbar disc, exceeding 90% similarity and outperforming existing artificial discs. This highlights the crucial role of fiber properties in disc stiffness regulation and enhances the understanding of biomechanical functions of structures and materials in the annulus fibrosus of human discs. These insights may inspire high‐performance artificial disc designs.
Biofilm Microenvironment‐Sensitive Anti‐Virulent and Immunomodulatory Nano‐on‐Nanodroplets to Combat Refractory Biofilm Infection Through Toxin Neutralization and Phagocytosis
Authors: Bose Somashree , Das Sujoy K 
Published: October 2024

AbstractBiofilm‐associated wound infection is principally perceived as the bacterial defense mechanism that hinders antibiotic penetration, causes toxin impairment, and suppresses the immunological responses of the host immune system. Several antibiofilm agents have been developed, but the least of these agents can simultaneously cornerstone on the biofilm‐associated immunosuppression and bacterial toxin‐induced cellular dysfunction. Inspired by the fusogenic property of nanodroplets and immunomodulatory functions of metal nanoparticles, biofilm targeted anti‐virulent immunomodulatory cationic nanoparticle shelled nanodroplets (C‐AgND) is fabricated to completely disintegrate and eradicate the Staphylococcus aureus (S. aureus) biofilm. The specific binding of C‐AgND neutralizes the negatively charged EPS layer, causing their destabilization followed by penetration of the nanoformulation into the biofilm matrix, killing the persister cells. Consequently, C‐AgND eliminates the virulence property of the S. aureus biofilm through α‐hemolysin neutralization. C‐AgND promotes a strong immunomodulatory effect by polarizing macrophages into their M1 phenotype to induce phagocytosis of the disintegrated biofilm‐released residual cells, rejuvenating the host's innate immune responses for the complete eradication of the biofilm. Moreover, the ex vivo skin wound infection model illustrates an excellent biofilm eradication efficacy of C‐AgND in comparison to the commercial ones, rendering them to be a promising replacement of existing antibiofilm agents in clinical application.
3D Micropatterning With Thermochromic Polymer Microfiber
Authors: Lee Jaeyu , Lee Kyung Jin 
Published: October 2024

AbstractAlthough 3D micropattern has received considerable attention due to their remarkable usability, the introduction of specific functions, such as “chromism”, is still a challenge mainly due to the lack of adequate functional materials that can be introduced into 3D printing system. In this study, 3D micropatterns with temperature‐responsive properties are created by elaborately aligned thermochromic polymer microfibers using charge reversal electro‐jet writing (CREW) method with a 3D printer. A reversible color change in response to the temperature change is exhibited in the micropattern, displaying various chromic colors, such as red, blue, and black, at their own thermochromic temperatures. Multiple‐color phases can be sequentially expressed in a single structure by incorporating pigments of different colors with distinguishable color shift ranges. Various patterning methods are proposed for manufacturing diverse patterns and demonstrating applications using combinations of color. In addition to directly increasing temperature, the thermochromic process of micropatterns can be induced by heat generated from external factors using electrical energy. These 3D thermochromic micropatterns using the CREW method can be extended to various fields, including sensors, clothing, and anti‐counterfeiting.
Heteroatom‐Embedded Spiro[Fluorene‐9,9′‐Xanthene]‐Based Electron Transport Materials for Improved Driving Voltage and Efficiency in Phosphorescent Organic Light‐Emitting Diodes
Authors: Kim Byeonghun , Han SeungWon , Lee Jun Yeob 
Published: October 2024

AbstractThe organic material 9,9‐spirobifluorene (SBF) is a useful building block for the construction of organic light‐emitting diodes owing to its rigid molecular structure, good charge transport properties, and high triplet energy. However, the electron transport properties of the SBF‐derived electron transport materials (ETMs) are currently not good enough and should be improved. In this work, two ETMs derived from spiro[fluorene‐9,9′‐xanthene] (SFX) and spiro[cyclopenta[1,2‐b:5,4‐b′] dipyridine‐5,9′‐xanthene] (SPX) is developed to enhance the electron transport properties and triplet energy of the SBF‐derived ETMs. The SFX core can increase the triplet energy by disconnecting the conjugation on the xanthene part and SPX can improve the electron transport properties through the incorporation of two nitrogen atoms in the fluorene part of the SFX core. The SFX and SPX cores are substituted with diphenyltriazine to produce high mobility and high triplet energy ETMs. As a result, the SFX and SPX‐based ETMs showed high triplet energy of over 2.95 eV compared with 2.53 eV of the SBF‐derived ETM; in addition, the SPX‐derived ETM demonstrated higher mobility than the SBF‐derived ETM. As a result, the SPX‐derived ETM achieved lowered driving voltage and increased external quantum efficiency compared to other ETMs derived from SBF and SFX.
Digital image analysis of gas bypassing and mixing in gas‐fluidized bed: Effect of particle shape
Authors: Chouhan Shreya , Neogi Ajita , Mohanta Hare K. , Sharma Arvind Kumar , Goyal Navneet , Sande Priya C. 
Published: October 2024

AbstractThe study investigates effect of particle shape on gas bypassing and mixing of gas‐fluidized Geldart A particles. A shallow fluidized bed (FB), configured at benchscale, was used with digital image analysis (DIA) for the investigation. The extent of scatter of tracer particles throughout the bed was assessed from DIA images of defluidized powder. A novel method employing Jupyter notebook software, was used to directly determine Mixing Index from digital images. Remarkably, platelet‐shaped China clay powder displayed the best mixing characteristics (Mixing Index: 0.79) with no significant bypassing. Angular shaped Quartz displayed moderate mixing (Mixing Index: 0.67), but high bypassing (Bypassing Index: 0.75). Contrary to conventional assumptions, spherical‐shaped diatomite exhibited poor mixing (Mixing Index: 0.61) with the highest bypassing (Bypassing Index: 0.82). Platelet particles performed well even with fines removal. Most likely, particle shape significantly influenced the number of available particle contact points, tracer migration, and traceronparticle binding.
Thermally Assisted Microfluidics to Produce Chemically Equivalent Microgels with Tunable Network Morphologies
Authors: Rommel Dirk , Häßel Bernhard , Pietryszek Philip , Mork Matthias , Jung Oliver , Emondts Meike , Norkin Nikita , Doolaar Iris Christine , Kittel Yonca , Yazdani Ghazaleh , Omidinia‐Anarkoli Abdolrahman , Schweizerhof Sjören , Kim Kyoohyun , Mourran Ahmed , Möller Martin , Guck Jochen , De Laporte Laura 
Published: October 2024

AbstractAlthough micron‐sized microgels have become important building blocks in regenerative materials, offering decisive interactions with living matter, their chemical composition mostly significantly varies when their network morphology is tuned. Since cell behavior is simultaneously affected by the physical, chemical, and structural properties of the gel network, microgels with variable morphology but chemical equivalence are of interest. This work describes a new method to produce thermoresponsive microgels with defined mechanical properties, surface morphologies, and volume phase transition temperatures. A wide variety of microgels is synthesized by crosslinking monomers or star polymers at different temperatures using thermally assisted microfluidics. The diversification of microgels with different network structures and morphologies but of chemical equivalence offers a new platform of microgel building blocks with the ability to undergo phase transition at physiological temperatures. The method holds high potential to create soft and dynamic materials while maintaining the chemical composition for a wide variety of applications in biomedicine.
Programmable C−N Bond Formation through Radical‐Mediated Chemistry in Plasma‐Microdroplet Fusion
Authors: Grooms Alexander J. , Huttner Robert T. , Stockwell Mackenzie , Tadese Leah , Marcelo Isabella M. , Kass Anthony , Badu‐Tawiah Abraham K. 
Published: October 2024

AbstractNon‐thermal plasma discharge produced in the wake of charged microdroplets is found to facilitate catalyst‐free radical mediated hydrazine cross‐coupling reactions without the use of external light source, heat, precious metal complex, or trapping agents. A plasma‐microdroplet fusion platform is utilized for introduction of hydrazine reagent that undergoes homolytic cleavage forming radical intermediate species. The non‐thermal plasma discharge that causes the cleavage originates from a chemically etched silica capillary. The coupling of the radical intermediates gives various products. Plasma‐microdroplet fusion occurs online in a programmable reaction platform allowing direct process optimization and product validation via mass spectrometry. The platform is applied herein with a variety of hydrazine substrates, enabling i) self‐coupling to form secondary amines with identical N‐substitutions, ii) cross‐coupling to afford secondary amine with different N‐substituents, iii) cross‐coupling followed by in situ dehydrogenation to give the corresponding aryl‐aldimines with two unique N‐substitutions, and iv) cascade heterocyclic carbazole derivatives formation. These unique reactions were made possible in the charged microdroplet environment through our ability to program conditions such as reagent concentration (i. e., flow rate), microdroplet reactivity (i. e., presence or absence of plasma), and reaction timescale (i. e., operational mode of the source). The selected program is implemented in a co‐axial spray format, which is found to be advantageous over the conventional one‐pot single emitter electrospray‐based microdroplet reactions.
The Photodynamic Agent Designed by Involvement of Hydrogen Atom Transfer for Enhancing Photodynamic Therapy
Authors: Fan Zhuo , Teng Kun‐Xu , Xu Yuan‐Yuan , Niu Li‐Ya , Yang Qing‐Zheng 
Published: October 2024

AbstractAlthough Type‐I photodynamic therapy has attracted increasingly growing interest due to its reduced dependence on oxygen, the design of effective Type‐I photosensitizers remains a challenge. In this work, we report a design strategy for Type‐I photosensitizers by the involvement of hydrogen atom transfer (HAT). As a proof of concept, a HAT‐involved Type‐I PS, which simultaneously generates superoxide and carbon‐centered radicals under light‐irradiation, was synthesized. This photosensitizer is comprised of a fluorene‐substituted BODIPY unit as an electron acceptor covalently linked with a triphenylamine moiety as an electron donor. Under light‐irradiation, photo‐induced intramolecular electron transfer occurs to generate the BODIPY anion radical and triphenylamine cation radical. The former transfers electrons to oxygen to generate O2−⋅, while the latter loses a proton to produce a benzyl carbon‐centered radical which is well characterized. The resulting carbon‐centered radicals efficiently oxidize NADH by HAT reaction. This photosensitizer demonstrates remarkable photocytotoxicity even under hypoxic conditions, along with outstanding in vivo antitumor efficacy in mouse models bearing HeLa tumors. This work offers a novel strategy for the design of Type‐I photosensitizers by involvement of HAT.
Live‐Cell Identification of Inhibitors of the Lipid Transfer Protein CERT Using Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET)
Authors: Kirmpaki Maria‐Anna , Saied Essa M. , Schumacher Fabian , Prause Kevin , Kleuser Burkhard , Arenz Christoph 
Published: October 2024

AbstractA BRET system is described, in which Nanoluciferase was fused to the lipid transfer protein CERT for efficient energy transfer to a Nile red‐labeled ceramide, which is either directly bound to CERT or transported to the adjacent Golgi membrane. Bulk formation of sphingomyelin, a major plasma membrane component in mammals, is dependent on CERT‐mediated transfer of its predecessor ceramide. CERT is considered a promising drug target but no direct cell‐based methods exist to efficiently identify inhibitors. The utility of the method was demonstrated by a library of 140 derivatives of the CERT inhibitor HPA‐12. These were obtained in a combinatorial synthesis using solid‐phase transacylation. Screening of the library led to six compounds that were picked and confirmed to be superior to HPA‐12 in a subsequent dose‐response study and also in an orthogonal lipidomics analysis.
Hydroxyl‐Binding Induced Hydrogen Bond Network Connectivity on Ru‐based Catalysts for Efficient Alkaline Hydrogen Oxidation Electrocatalysis
Authors: Yue Jianchao , Li Yunbo , Yang Chaoyi , Luo Wei 
Published: October 2024

AbstractUnderstanding the role of adsorbed intermediates at the polarized catalyst‐electrolyte interface on the structure of electrical double layer (EDL) is essential for developing highly efficient electrocatalysts. Here, we prepared a series of unconventional face‐centered‐cubic (fcc) phase Ru‐based catalysts (i.e. fcc‐Ru, fcc‐RuCr, and fcc‐RuCrW) by rational tuning the binding energetics of hydroxyl intermediate to engineer the electrochemical interface and boost the performance of alkaline hydrogen oxidation reaction (HOR). The introduction of oxyphilic metals Cr and W can regulate the orbital occupation of Ru, promote the adsorption of hydroxyl species, resulting in an anomalous behavior that HOR performance under alkaline media exceeds acidic media. Experimental results and theoretical calculations unravel that the modulated adsorption of hydroxyl species on the electrode surface are responsible for the reconstruction of interfacial water structure and dynamic evolution of free water molecules from nearest to the electrode surface to above the gap region in the EDL, thereby leading to significantly increased water connectivity and hydrogen bond network. Our work reveals a new understanding of the surface intermediates in controlling the dynamic process of interfacial water and hydrogen bonding network in HOR electrocatalysis, and will guide rational design of advanced electrocatalysts through electrochemical interfacial engineering.
Evolution of Frustrated Coordination in Eutectic Electrolyte Driven by Ligand Asymmetry toward High‐Performance Zinc Batteries
Authors: Deng Wenjing , Deng Zhiping , Zhang Xuzi , Chen Yimei , Feng Renfei , Li Ge , Wang Xiaolei 
Published: October 2024

AbstractEutectic electrolytes hold promise for aqueous zinc metal batteries in sustainable energy storage chemistries, yet improvement from perspective of molecule configurational engineering are ambiguous. Herein, we propose design strategy of increasing asymmetric molecular geometry in organic ligands to regulate frustrated coordination and disordered structure for eutectic electrolytes toward enhanced zinc metal batteries. The introduced asymmetry in eutectic component gives rise to relatively weak coordination strength and configurational disorder interaction among cation‐anion‐ligand, leading to suppressed local aggregation, steady eutectic phase and improved Zn2+ diffusion kinetics. Such highly frustrated coordination state also enables disruption of hydrogen bonding network and reinforcement of anion participation, which results in confined side reactions, decreased water activity and the formation of inorganic‐enriched solid electrolyte interphase. In comparison to highly symmetric ligands, asymmetric ligand‐involved eutectic electrolytes with configurational disorder deliver high Coulombic efficiency of 99.4 %, stabilized Zn plating/stripping of 5000 h and impressive rate capability even under harsh conditions such as small N/P, low temperature. The rationale in this work advances the deep understanding of asymmetric molecular engineering in eutectic electrolytes and showcases suitability of frustrated coordination to achieve high‐performance zinc metal batteries.
Pyrolytic Carbon: An Inexpensive, Robust, and Versatile Electrode for Synthetic Organic Electrochemistry
Authors: Ewing Tamara El‐Hayek , Kurig Nils , Yamaki Yoshio Robert , Sun Jiawei , Knowles Timothy R. , Gollapudi Asha , Kawamata Yu , Baran Phil S. 
Published: October 2024

AbstractSynthetic organic electrochemistry is recognized as one of the most sustainable forms of redox chemistry that can enable a wide variety of useful transformations. In this study, readily prepared pyrolytic carbon electrodes are explored in several powerful rAP transformations as well as C−C and C−N bond forming reactions. Pyrolytic carbon provides an alternative to classic amorphous carbon‐based materials that are either expensive or ill‐suited to large‐scale flow reactions.