bluuebunny/crossref_metadata_2025_split huggingface dataset:
Erythroplasia of Queyrat Treated with 5% Imiquimod Cream — Case Report Emphasizing the Role of Human Papilloma Virus Testing in a Clinical Setting
Authors: Chiriac Anca , Brzezinski Piotr , Podoleanu Cristian , Stolnicu Simona 
Published: July 2017

AbstractBackground:Anogenital premalignancies and malignancies often affect females and males, and human papillomavirus infection plays a crucial role in their etiopathogenesis. These lesions are very important and represent an immense public health burden.Case presentation:A 78-year-old Caucasian male presented to the Dermatology Unit for persistent, slowly progressing, well-demarcated, erythematous plaques on the glans penis, observed by the patient 18 months prior to the consultation. Variable topical treatments were applied, with no improvement and with the denial of a punch biopsy. A clinical diagnosis of erythroplasia of Queyrat was established and the test for HPV revealed an association with subtype 16 (which excluded other benign inflammatory conditions). Positive results were obtained after 4 weeks of topical application of 5% imiquimod cream, once daily, 5 times a week.Conclusion:Erythroplasia of Queyrat should be diagnosed in a non-compliant patient based on the clinical picture and HPV testing even in the absence of a biopsy, and a non-surgical treatment should be initiated immediately.
Alopecia Areata and Suicide Ideation
Authors: Chiriac Anca , Podoleanu Cristian , Stolnicu Simona 
Published: July 2017

Abstract
Alopecia areata represents an autoimmune process against an unidentified autoantigen in the follicle of the hair, which affects all ages, from young children (a few months old) to elderly patients. Alopecia areata has an important impact on the quality of life, leading to a predisposition towards anxiety and depression, especially if the patients are treated with corticoid therapy that heightens the risk for such psychiatric disorders. We present the case of a patient with alopecia areata who was diagnosed at the age of 18 months, and had been followed-up until the age of 27 years.
Risk Factors for Congenital Hearing Loss: Which Are the Most Relevant?
Authors: Balázs Andor , Neagoș Adriana 
Published: July 2017

AbstractIntroduction:Congenital hearing loss is a multifactorial disease that affects mostly premature newborns exposed to certain risk factors. The recent widespread introduction of newborn hearing screening in Tîrgu Mureş, Romania prompted the need for a multidisciplinary centralized study on the subject.Case series presentation:We collected data from 340 neonates born in 2014 who had undergone neonatal hearing screening with otoacoustic emissions. Our focus group consisted of 137 neonates with a gestational age of less than 37 weeks. We collected data on the pregnancy, birth, and perinatal period, and then analyzed the impact of infections, treatments — with or without ototoxic potential, hypoxia, mechanical ventilation, intrauterine malnutrition, and the presence of malformations. Premature neonates showed a significantly higher number of REFER results than those with a normal gestational age. The rates of low birthweight, head circumference, and infant length; low Apgar scores; hypoxia in the perinatal period; the presence of placental pathology, mechanical ventilation, and perinatal infections; and the concomitant potentially ototoxic treatment were significantly higher in the REFER group. The age of the mother, bilirubin levels, and oxytocin use during birth did not prove to be relevant.Conclusions:Known risk factors can cause hearing loss in a considerable number of newborns and mandate a multidisciplinary approach to the problem at hand. The referral of these patients to an ENT specialist and their correct management according to an individualized hearing recovery plan is crucial
Transformation of Aggressive Non-Hodgkin Lymphoma in Acute Lymphoblastic Leukemia
Authors: Benedek István , Lázár Erzsébet , Pakucs Annamária , Köpeczi Judit-Beáta , Benedek István , Jakab Szende , Sándor-Kéri Johanna 
Published: July 2017

AbstractDiffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL), representing up to 30 percent of all lymphomas. DLBCL is a fast-growing, aggressive form of NHL, which can appear as a transformation from a less aggressive form of lymphoma or can be de novo pathology. The following article describes the case of a 55-year-old female patient who developed a DLBCL as a second malignancy after an R-CHOP-treated marginal zone splenic lymphoma. This was followed by the transformation of the DLBCL into an aggressive acute lymphoblastic leukemia, for which the patient needed aggressive treatment according to the international acute lymphoblastic leukemia protocol.
Complex Comparison of Bavarian and Bohemian Forest National Parks from Geographical Perspective: Is there More Similarity or Difference?
Authors: Janík Tomáš , Romportl Dušan 
Published: July 2017

Abstract
This article focuses on comparison of the landscape of two National Parks (Bavarian and Bohemian Forest), which together create the largest area of wilderness in Central Europe. The article shows how different they are in social-economic and physical-geographical perspective. Social and economic conditions were introduced from perspective of path dependency and recent situation and its perception. Furthermore, we integrated social-economic and environmental perspective in the ecosystem services concept. Despite the lesser number tourists arriving to the Bavarian part of the area, perception is better than among mayors of municipalities on the Czech side. Different history, management and top-down and bottom-up approaches usage can explain these differences. The typologies of environmental conditions help us to distinguish differences between both National Parks. In the Bavarian Forest we can find more equal share of forests (coniferous, broad-leaved, mixed) and surprisingly, thanks to large unmanaged part bigger relative share of regenerating forest landscapes than in the Bohemian Forest. Physical-geographical typology distinguishes five classes. Relative distribution of the classes is similar, but we can determine area of high plateau mainly on Czech side and on the other hand class of steeper terrain is located mainly in Bavarian Forest. Ecosystem services was presented by integrating landscape capacity analysis showing small differences between both National Parks in this case and no relation between land cover and attractiveness for tourism.
Spatio-Temporal Dynamics in Land Use and Habitat Fragmentation within a Protected Area Dedicated to Tourism in a Sudanian Savanna of West Africa
Authors: Dimobe Kangbéni , Goetze Dethardt , Ouédraogo Amadé , Forkuor Gerald , Wala Kpérkouma , Porembski Stefan , Thiombiano Adjima 
Published: July 2017

AbstractNazinga Game Ranch (NGR) is a reserve in Burkina Faso involving local communities for securing biodiversity through sustainable management. Yet, its ecosystems are threatened by increasing number of elephants and illegal human activities. Renowned as a model of wildlife participatory management, NGR has mainly been studied for its animal wildlife only. The aim of this study was to uncover ecological effects of recent land management on savanna habitats including tourism, and to conclude on more sustainable options, land use/land cover (LULC) changes and vegetation dynamics in NGR were analyzed. This was accomplished with multi-temporal change detection using Landsat images of 1984, 2002 and 2013 to map seven representative LULC classification categories, and quantitative indices of landscape metrics. The results showed that the LULC dynamics in NGR from 1984 to 2013 was mainly characterized by an expansion of gallery forest, tree savanna and agricultural area and a reduction of shrub savanna, woodland and bare soils. From 2002 to 2013, fragmentation in all land cover types increased at the landscape level, whereas at the class level, it decreased for woodland. Our findings provided evidence of habitat degradation in NGR, due to extensive agriculture, tourism and growing of elephants’ population. According to the original management goals and the purposes of the reserve, both fauna and tourism are to be maintained and sustained in a sustainable way. Adaptation of land use and targeted wildlife management are the main requirements for avoiding further degradation of vegetation and thus of the existence basis of local inhabitants, animals and tourism.
“Pool it or lose it?” – a contrastive analysis of discourses concerning EU military integration and demilitarisation in the Baltic Sea
Authors: Heinikoski Saila 
Published: July 2017

AbstractThis article illustrates that justification for EU military integration is sought with imperatives related to the economy, security, EU integration, and demands of citizens of the Member States. However, EU Treaties in terms of the improvement of military capabilities are not considered as a justification, but the European Union appears to be more of a power-enhancing realist actor rather than a normative one. As a counterexample to the European discourses, I discuss the case of the demilitarisation of the Åland Islands, in which case treaties perfectly justify demilitarization. I conclude that the development of European military integration is justified by political imperatives, but the demilitarization of the Åland Islands is supported with reference to agreements, which illustrate the differences in justifying military force and its absence. It is concluded that while the European Union appears as a realist actor in terms of defence, Finland complies with the image of a normative power as far as the Åland Islands are concerned.
Teaching foreign language to adults from the aspects of psychodidactic conception of education
Authors: Petrová Gabriela , Kozárová Nina 
Published: July 2017

Abstract
Psychodidactic themes focused on the educational context have recently been resolved in both theoretical and research work. These themes are connected with general didactics, educational psychology, individual subject didactics, linguistics, philosophy, anthropology and neurosciences. Since the psychodidactic context of education is a widespectral and interdisciplinary topic, the present contribution deals with the issues of psychological aspects in the context of foreign language learning of adults. Good lecturers are looking for ways to help participants develop key competences. The support of lecturers has a chance to be successful especially when it is systematic and includes high-quality theoretical preparation. The aim of this paper is to attract attention, to a theoretical level, to using psychodidactic aspects during foreign language training of adults as well as to the building of competences necessary for the self- realisation of training course participants.
Composition and Concentration of Serum Fatty Acids of Phospholipids Depend on Tumour Location and Disease Progression in Colorectal Patients
Authors: Bugajska Jolanta , Berska Joanna , Hodorowicz-Zaniewska Diana , Sztefko Krystyna 
Published: July 2017

SummaryBackground: Polyunsaturated fatty acids (PUFAs) play a role in the development/progression of colon cancer. The aim of the study was to assess the relation between serum phospholipids PUFAs, colorectal tumour localization and disease progression. Methods: A total of 67 patients (18 with proximal colon, 17 with distal colon and 32 with rectal tumour localization) as well as 16 controls were studied. One year after surgery, 33 patients had disease progression. Serum levels of C16:1(n-7), C18:1(n-9), C18:3(n-3), C20:5(n-3), C22:6(n- 3), C18:2(n-6), C20:2(n-6), C20:4(n-6) fatty acids of se - rum phospholipids were quantitatively measured before surgery by gas-chromatography. Results: Significantly higher mean value of C18:2, as compared to control, has been noted only for patients with proximal (p<0.05) and distal tumour (p<0.03) localization. The lower mean level of C20:5 and unsaturation index (UI) were observed in colorectal cancer patients regardless the tumour localization, but the statistical difference was noted only for patients with proximal tumours (p<0.05, p<0.03). In patients with proximal tumours, significantly lower mean level of C20:4 and UI were noted in patients with disease progression, as compared to patients with proximal tumours without disease progression (p<0.05). Conclusion: The evaluation of PUFAs as a risk/prognostic factor in colorectal cancer patients should take into account tumour localization as a dependent variable.
ISO 15189 Accreditation: Navigation Between Quality Management and Patient Safety
Authors: Plebani Mario , Sciacovelli Laura 
Published: July 2017

SummaryAccreditation is a valuable resource for clinical laboratories and the development of an International Standard for their accreditation represented a milestone on the path towards improved quality and safety in laboratory medicine. The recent revision of the International Standard, ISO 15189, has further strengthened its value not only for improving the quality system of a clinical laboratory but also for better answering the request for competence, focus on customers’ needs and ultimate value of laboratory services. Although in some countries more general standards such as ISO 9001 for quality systems or ISO 17025 for testing laboratories are still used, there is increasing recognition of the value of ISO 15189 as the most appropriate and useful standard for the accreditation of medical laboratories. In fact, only this International Standard recognizes the importance of all steps of the total testing process, namely extra-analytical phases, the need to focus on technical competence in addition to quality systems, and the focus on customers’ needs. However, the number of accredited laboratories largely varies between European countries and also major differences affect the approaches to accreditation promoted by the national bodies. In particular, some national accreditation bodies perpetuate the use of fixed scopes, while the European co-operation for accreditation (EA) and the European Federation of Laboratory Medicine (EFLM) Working Group promote the use of flexible scopes. Major issues in clinical laboratory accreditation are the verification of examination procedures for imprecision, trueness and diagnostic accuracy and for estimating measurement uncertainty. In addition, quality indicators (QIs) are a fundamental requirement of the ISO 15189 International Standard.
A Survey of Helminth Infections in the Black Rat from Stara Zagora District, Bulgaria
Authors: Iliev Petar T. , Georgiev Georgi Zh. , Kirkova Zvezdelina T. , Chakarova Borislava G. 
Published: July 2017

Abstract
A field study was conducted to disclose the prevalence of different helminth parasites in the black rat, Rattus rattus, in some regions of Stara Zagora district, Bulgaria. Out of 67 examined rats, 53 (79.1%) were found to be positive. Helminths of three classes were detected such as Cestoda: Hymenolepis diminuta (47.8%), Hymenolepis nana (43.3%), Taenia taeniaeformis larvae (7.5%), Taenia polyacantha larvae (1.5%); Secernentea: Syphacia obvelata (4.5%), Aspiculuris tetraptera (3.0%) and Adenophorea: Capillaria hepatica (9.0%), Trichuris muris (3.0%). Of all the investigated rats, 27 (40.3%) were infected by one helminth species and 26 (38.8%) by more than one. Hymenolepis diminuta was a predominant species in cases of single infections (23.9%). The most frequent co-infections were observed by H. nana and H. diminuta (16.4%).
The Sheffer stroke operation reducts of basic algebras
Authors: Oner Tahsin , Senturk Ibrahim 
Published: July 2017

Abstract
In this study, a term operation Sheffer stroke is presented in a given basic algebra 𝒜 and the properties of the Sheffer stroke reduct of 𝒜 are examined. In addition, we qualify such Sheffer stroke basic algebras. Finally, we construct a bridge between Sheffer stroke basic algebras and Boolean algebras.
Automorphism groups with some finiteness conditions
Authors: Pióro Konrad 
Published: July 2017

AbstractAll considered groups are torsion or do not contain infinitely generated subgroups. If such a groupGacts transitively on a connected algebraA, then all elements ofAhave the same stabilizer, so this stabilizer is a normal subgroup (it is also shown that these facts are not true for arbitrary groups). Hence the automorphism group Aut(A) is a homomorphic image ofG. In particular, if the action ofGis, in addition, faithful, thenGis isomorphic to Aut(A). By these results we first obtain that for each (not necessarily connected) algebraA, if all of its Aut(A)-orbits are connected, then Aut(A) is a subdirect product of automorphism groups of these orbits. Secondly, connected components of Aut(A)-orbits have automorphism extension property.Next, we show that ifAis a connected algebra such that Aut(A) acts transitively on it, then the group structure of Aut(A) may be transported onAsuch that the left multiplications are all automorphisms ofAand the right multiplications are all unary term operations ofA. Hence all the unary term operations ofAare bijective, so they generate a subgroup of the group of all bijections of the carrier ofA. It is shown that this group is anti-isomorphic to Aut(A). Thus the Birkhoff’s construction of an algebra with a given group of automorphisms is unique in some sense when restricted to groups we consider here.The Birkhoff’s construction can be slightly modified so as to obtain a smaller set of operations. In fact, it is enough to take the right multiplications by generators. Moreover, we show that this is the best possible lower bound for the number of unary operations in the case of groups considered here. If we admit non-unary operations, then for finite and countable groups we can reduce the number of operations to one binary operation. On the other hand, ifAis a connected algebra such that Aut(A) is torsion and acts onAtransitively, then each element generatesA. Hence ifAis such an algebra with an uncountable group Aut(A), then the cardinality of the set of operations ofAis greater or equal than the cardinality of Aut(A).
Abundant semigroups with a *-normal idempotent
Authors: Hou Yonglin , Guo Junying , Guo Xiaojiang 
Published: July 2017

Abstract
The notion of *-normal idempotents is introduced. The structure theorem for abundant semigroups with a *-normal idempotent is obtained. As its applications, we establish the construction theorem of naturally ordered abundant semigroups with a greatest idempotent.
Monotonicity results for delta fractional differences revisited
Authors: Erbe Lynn , Goodrich Christopher S. , Jia Baoguo , Peterson Allan 
Published: July 2017

Abstract
In this paper, by means of a recently obtained inequality, we study the delta fractional difference, and we obtain the following interrelated theorems, which improve recent results in the literature.

Theorem A

Assume that f : ℕ
a
→ ℝ and that

Δ
a
ν

f
(
t
)

$\Delta^\nu_af(t)$

≥ 0, for each
t ∈ ℕ
a+2−ν
, with 1 < ν < 2. If

f
(
a
+
1
)
≥

ν

k
+
2

f
(
a
)
,

$f(a+1) \geq \frac{\nu}{k+2}f(a),$

for each k ∈ ℕ0, then Δ f(t) ≥ 0 for t ∈ ℕ
a+1.

Theorem B

Assume that f : ℕ
a
→ ℝ and that

Δ
a
ν

f
(
t
)

$\Delta^\nu_af(t)$

≥ 0, for each t ∈ ℕ
a+2−ν
, with 1 < ν < 2. If

f
(
a
+
2
)
≥

ν

k
+
1

f
(
a
+
1
)
+

(
k
+
1
−
ν
)
ν

(
k
+
2
)
(
k
+
3
)

f
(
a
)

$$f(a+2)\geq\displaystyle\frac{\nu}{k+1}f(a+1)+\frac{(k+1-\nu)\nu}{(k+2)(k+3)}f(a) $$

for each k ∈ ℕ1, then Δ f(t) ≥ 0 for t ∈ ℕ
a+2.

Theorem C

Assume that f : ℕ
a
→ ℝ and that

Δ
a
ν

f
(
t
)

$\Delta^\nu_af(t)$

≥ 0, for each t ∈ ℕ
a+2−ν
, with 1 < ν < 2. If

f
(
a
+
3
)
≥

ν
k

f
(
a
+
2
)
+

(
k
−
ν
)
ν

k
(
k
+
1
)

f
(
a
+
1
)
+

(
k
+
1
−
ν
)
(
k
−
ν
)
ν

(
k
+
2
)
(
k
+
1
)
k

f
(
a
)

$$f(a+3)\geq\displaystyle\frac{\nu}{k}f(a+2)+\frac{(k-\nu)\nu}{k(k+1)}f(a+1)+\frac{(k+1-\nu)(k-\nu)\nu}{(k+2)(k+1)k}f(a) $$

for k ∈ ℕ2, then Δ f(t) ≥ 0, for
t ∈ ℕ
a+3.
In addition, we obtain the following result, which extends a recent result due to Atici and Uyanik.

Theorem D

Assume that f : ℕ
a
→ ℝ, Δ
N

f(t) ≥ 0 for t ∈ ℕ
a
, and (−1)
N−i
Δ
i

f(a) ≤ 0 for
i = 0, 1, …, N − 1. Then

Δ
a
ν

f
(
t
)

$\Delta^\nu_af(t)$

≥ 0 for
t ∈ ℕ
a+N−ν
.
On certain generalized matrix methods of convergence in (ℓ)-groups
Authors: Das Pratulananda , Savas Ekrem 
Published: July 2017

AbstractWe introduce a convergence of weightg: ℕ → [0, ∞) whereg(n) → ∞ andn/g(n) ↛ 0 with respect to a summability matrix methodAfor sequences (which generalizes the notion ofA-convergence of orderα, 0 <α≤ 1 [BOCCUTO, A.—DAS, P.:On matrix methods of convergence of order(α)in(ℓ)-groups, Filomat29(2015), 2069–2077] in a (ℓ)-group. We prove some basic results including a Cauchy-type criterion. Finally a closedness result for the space of such convergent sequences is proved.
Hankel determinant for a class of analytic functions involving conical domains defined by subordination
Authors: Annamalai Srinivasan , Sivasubramanian Srikandan , Ramachandran Chellakutty 
Published: July 2017

Abstract
Domains with conical sections is an underlying concept in the area of complex function theory although is an interesting topic and it deserves more attention. There has been many works focusing towards this area for the past two decades. However, the concept of Hankel determinant has not been studied so far. Exploiting this, we provide an estimate for the Hankel determinant with domains bounded by conical sections. The authors sincerely hope this article will revive and encourage the other researchers to obtain similar sort of estimates for other classes connected with conical domains. The concept of conical domains was introduced by Kanas and Wiśniowska.
On the internal approach to differential equations 2. The controllability structure
Authors: Chrastinová Veronika , Tryhuk Václav 
Published: July 2017

AbstractThe article concerns the geometrical theory of general systems Ω of partial differential equations in theabsolute sense, i.e., without any additional structure and subject to arbitrary change of variables in the widest possible meaning. The main result describes the uniquely determined composition series Ω0⊂ Ω1⊂ … ⊂ Ω where Ωkis the maximal system of differential equations “induced” by Ω such that the solution of Ωkdepends on arbitrary functions ofkindependent variables (on constants ifk= 0). This is a well-known result only for the particular case of underdetermined systems of ordinary differential equations. Then Ω = Ω1and we have the composition series Ω0⊂ Ω1= Ω where Ω0involves all first integrals of Ω, therefore Ω0is trivial (absent) in the controllable case. The general composition series Ω0⊂ Ω1⊂ … ⊂ Ω may be regarded as a “multidimensional” controllability structure for the partial differential equations.Though the result is conceptually clear, it cannot be included into the common jet theory framework of differential equations. Quite other and genuinely coordinate-free approach is introduced.
The Management of Selected Yeast Strains in Quantifying Terpene Flavours in Wine
Authors: Lengyel Ecaterina , Panaitescu Magda 
Published: July 2017

Abstract
This paper aims at studying the accumulation of free volatile terpene flavours (FVT) and bound precursor terpene flavours (BPT) under the action of 12 selected wine yeast strains (S1, S2, S3, S4, S5, S6, S7, S8, S9, S10, S11, S12). The importance of these flavours results from the fact that they confer wines a savoury, floral aroma; their amount is closely related to a series of factors, of which one makes the object of this analysis. The must under alcoholic fermentation comes from the Gârbova area (Sebeș-Apold Vineyard), obtained from the variety Muscat Ottonel. The 12 strains used in the alcoholic fermentation resulted in the determination of considerable amounts of terpene flavour compounds, between 370 μg/L and 1100 μg/L, which recommends their use in making quality wines.