bluuebunny/crossref_metadata_2025_split huggingface dataset:
First evidence on the occurrence of multi-mycotoxins and dietary risk exposure to AFB1 along the cassava value chain in Uganda
Authors: Oyesigye Elias , Cervini Carla , Oluwakayode Abimbola , Mahuku George , Medina Angel 
Published: September 2024

AbstractThis study investigated the occurrence and distribution of multiple mycotoxins (aflatoxin B1, B2, G1, G2, fumonisins B1, B2, ochratoxin A (OTA), deoxynivalenol (DON), zearalenone (ZEN), and citrinin (CIT)) in cassava products and as assessed the potential risk of aflatoxin B1 (AFB1) exposure among cassava consumers. A total of 192 samples of cassava products (96 flour and 96 chips, each with 48 samples from farmer and 48 from wholesaler) were analysed using LC/MS–MS. All positive samples irrespective of their origin (flour or chips) exhibited AFB1 levels exceeding the EU regulatory threshold of 5 µg/kg. The sum of fumonisins (FB1 + FB2), ZEN, and DON were significantly (P < 0.05) higher in cassava flour (14.3 µg/kg; 3.71 µg/kg; 25.1 µg/kg) compared to chips (6.54 µg/kg; 1.25 µg/kg; 0.25 µg/kg), respectively. Aflatoxins G2 was not detected in any of 192 samples. Cassava flour samples from farmers exhibited significantly (P < 0.05) higher mean concentrations of AFB1 (27.1 µg/kg), total aflatoxins (78.2 µg/kg), and ochratoxin A (79.6 µg/kg) in contrast to wholesalers, whose mean levels were notably lower at 8.91, 5.79 µg/kg, and 2.44 µg/kg, respectively, pointing the likely critical source of mycotoxin contamination. Cassava consumers in Northern Uganda are at a higher risk, with an estimated 2.06 cancer cases per 100,000 individuals per year compared to those in Eastern Uganda at 0.25. This study underscores the urgent need for interventions to manage aflatoxins in cassava flour, particularly at farm level in Northern Uganda. It accentuates a shift market to household-level sampling and the need for analytical methods targeting multiple mycotoxins.
The relationships between (dis-)empowering climate and basic psychological need satisfaction and frustration
Authors: Haberstock Stefanie , Schulte Lina , Seidel Johanna , Cowper Imogen , Pels Fabian 
Published: September 2024

AbstractIn the realm of sports, athlete wellbeing stands as a pivotal cornerstone for peak performance and personal growth. Within this context, the satisfaction of basic psychological needs (BPNs; i.e., autonomy, competence, and relatedness) plays a fundamental role. This study is rooted in self-determination theory and is the first to investigate how peer-created empowering climate (PCEC) and peer-created disempowering climate (PCDC) relate to BPN satisfaction and frustration. The study sample comprises 101 athletes from diverse team sports, including para- and non-para-athletes. Using adapted scales, the study cross-sectionally measures PCEC and PCDC as independent variables and BPN satisfaction and frustration as dependent variables in the context of team sports. The results show significant positive relationships between PCEC and BPN satisfaction across autonomy, competence, and relatedness. Conversely, PCDC shows positive relationships with BPN frustration regarding autonomy, competence, and relatedness. The research highlights the differential impacts of PCEC and PCDC on athletes’ needs, emphasizing how PCEC may positively influence satisfaction while PCDC relates to increased frustration. Notably, the study provides insights into the influential role of peers in meeting the basic psychological needs of athletes. These findings underscore the importance of interpersonal relationships in team sports and offer valuable insights for interventions to enhance athlete wellbeing and optimize performance.
The impact of histological subtype on postoperative recurrence pattern and timing in locally advanced esophagogastric junction cancer
Authors: Maeda Shinsuke , Ota Masaho , Ito Shunichi , Hosoda Kei 
Published: September 2024

Abstract
Purpose
The differences in tumor behavior between adenocarcinoma (AC) and squamous cell carcinoma (SCC) of the esophagogastric junction (EGJ) have yet to be well investigated. The purpose of this study was to gain insights that can contribute to tailored treatments and follow-up strategies by analyzing the correlation between histological subtypes and oncological outcomes.

Methods
A retrospective analysis was used to determine the characteristics of the histological subtypes of EGJ cancer by comparing the appearance of postoperative recurrence. A total of 102 consecutive patients with pathological stage IIA to IVA EGJ cancer, who underwent R0 surgery in our department from 2004 to 2020, were enrolled. The recurrence pattern, timing, survival, and potential prognostic factors were compared.

Results
After a median follow-up time of 70.1 months, the AC group demonstrated comparable lymph node failure-free survival (P = 0.291) and significantly worse non-lymphogenous recurrence-free survival (P = 0.035) than did the SCC group. A significantly longer period from surgery to recurrence was also observed in the AC group (P = 0.029). Multivariate analysis indicated that histological subtype (P = 0.015, 95% CI 1.24–7.28) was significantly correlated with the incidence of non-lymphogenous recurrence.

Conclusions
The pattern and timing of postoperative recurrence were significantly different between the histological subtypes of EGJ cancer. Compared with EGJ SCC, EGJ AC may have a greater tendency toward non-lymphogenous progression and a greater propensity for longer surgery-to-recurrence periods.
Recent advances in pharmaceutical cocrystals of theophylline
Authors: Jia Yanxiao , Yang Dezhi , Wang Wenwen , Hu Kun , Yan Min , Zhang Li , Gao Li , Lu Yang 
Published: September 2024

AbstractCurrently, cocrystallization is a promising strategy for tailoring the physicochemical properties of active pharmaceutical ingredients. Theophylline, an alkaloid and the most primary metabolite of caffeine, is a readily available compound found in tea and coffee. It functions primarily as a bronchodilator and respiratory stimulant, making it a mainstay treatment for lung diseases like asthma. Theophylline’s additional potential benefits, including anti-inflammatory and anticancer properties, and its possible role in neurological disorders, have garnered significant research interest. Cocrystal formation presents a viable approach to improve the physicochemical properties of theophylline and potentially mitigate its toxic effects. This review comprehensively explores several successful studies that utilized cocrystallization to favorably alter the physicochemical properties of theophylline or its CCF. Notably, cocrystals can not only enhance the solubility and bioavailability of theophylline but also exhibit synergistic effects with other APIs. The review further delves into the hydrogen bonding sites within the theophylline structure and the hydrogen bonding networks observed in cocrystal structures.
Graphical Abstract
Structure characterization and immunoactivity on dendritic cells of two neutral polysaccharides from Dictyophora rubrovalvata
Authors: Huang Ni , Yang Yi-Na , Huang Jia , Shao Hui-Yan , Li Yan-Lang , Qin Shi-Hui , Li Han-Fen , Shen Xiao-Jiang , Yang Liu , Hu Jiang-Miao 
Published: September 2024

AbstractDictyophora rubrovalvata is a valuable fungus homologous to food and medicine, and its polysaccharide have been gaining increasing attention because of its plentiful activity. However, the structure and activity of its homogeneous polysaccharide have not been studied enough. In this study, two polysaccharides DRP-I and DRP-II were purified from D. rubrovalvata. Their structures were characterized by chemical composition, monosaccharide composition analysis, methylation analysis and nuclear magnetic resonance spectroscopy. The results showed that DRP-I and DRP-II were neutral heteropolysaccharides with molecular weights of 5.79 × 103 and 1.25 × 104 Da, respectively, which were composed of mannose, galactose, glucose, xylose and fucose. The main chains were → 6)-α-D-Galp-(1 → 6)-α-D-Galp-(2,1 → 6)-α-D-Manp-(2,1 → 6)-α-D-Galp-(1, and branch chains were β-D-Xylp-(1 → 3)-α-L-Fucp-(1 → 4)-α-D-Manp-(1 → and α-D-Galp-(1 → 3)-α-D-Galp-(1 → . The in vitro immunoactivity assays on dendritic cells showed that DRP-I and DRP-II could up-regulate the expression of IL-10 and IL-6 and inhibit the expression of TNF-α in a concentration-dependent manner. This research indicated that DRP-I and DRP-II possessed immunoactivity by balancing the excessive inflammation, and molecular weight is an important factor affecting immunoactivity.
Graphical Abstract
Integration of a hybrid vibration prediction model for railways into noise mapping software: methodology, assumptions and demonstration
Authors: Reumers Pieter , Degrande Geert , Lombaert Geert , Thompson David J. , Ntotsios Evangelos , Bouvet Pascal , Nélain Brice , Nuber Andreas 
Published: September 2024

Abstract
Within the SILVARSTAR project, a user-friendly frequency-based hybrid prediction tool has been developed to assess the environmental impact of railway-induced vibration. This tool is integrated in existing noise mapping software. Following modern vibration standards and guidelines, the vibration velocity level in a building in each frequency band is expressed as the sum of a force density (source term), line source transfer mobility (propagation term) and building correction factor (receiver term). A hybrid approach is used that allows for a combination of experimental data and numerical predictions, providing increased flexibility and applicability. The train and track properties can be selected from a database or entered as numerical values. The user can select soil impedance and transfer functions from a database, pre-computed for a wide range of parameters with state-of-the-art models. An experimental database of force densities, transfer functions, free field vibration and input parameters is also provided. The building response is estimated by means of building correction factors. Assumptions within the modelling approach are made to reduce computation time but these can influence prediction accuracy; this is quantified for the case of a nominal intercity train running at different speeds on a ballasted track supported by homogeneous soil of varying stiffness. The paper focuses on the influence of these parameters on the compliance of the track–soil system and the free field response. We also demonstrate the use and discuss the validation of the vibration prediction tool for the case of a high-speed train running on a ballasted track in Lincent (Belgium).
Self-Supervised 3D Semantic Occupancy Prediction from Multi-View 2D Surround Images
Authors: Abualhanud S. , Erahan E. , Mehltretter M. 
Published: September 2024

AbstractAn accurate 3D representation of the geometry and semantics of an environment builds the basis for a large variety of downstream tasks and is essential for autonomous driving related tasks such as path planning and obstacle avoidance. The focus of this work is put on 3D semantic occupancy prediction, i.e., the reconstruction of a scene as a voxel grid where each voxel is assigned both an occupancy and a semantic label. We present a Convolutional Neural Network-based method that utilizes multiple color images from a surround-view setup with minimal overlap, together with the associated interior and exterior camera parameters as input, to reconstruct the observed environment as a 3D semantic occupancy map. To account for the ill-posed nature of reconstructing a 3D representation from monocular 2D images, the image information is integrated over time: Under the assumption that the camera setup is moving, images from consecutive time steps are used to form a multi-view stereo setup. In exhaustive experiments, we investigate the challenges presented by dynamic objects and the possibilities of training the proposed method with either 3D or 2D reference data. Latter being motivated by the comparably higher costs of generating and annotating 3D ground truth data. Moreover, we present and investigate a novel self-supervised training scheme that does not require any geometric reference data, but only relies on sparse semantic ground truth. An evaluation on the Occ3D dataset, including a comparison against current state-of-the-art self-supervised methods from the literature, demonstrates the potential of our self-supervised variant.
Postdigital Game-Based Learning: Complexity, Continuity, and Contingency
Authors: Bacalja Alexander 
Published: September 2024

AbstractDiscourses that establish the potential learning benefits of digital games for schooling too often focus on learning as a product of relations between student and gameplay, adopting overly deterministic positions that have long been associated with digital technologies and education. This paper draws on ideas from postdigitalism to problematise such narrow conceptualisations of digital game-based learning (DGBL). The analysis of one Australian school’s experience of incorporating digital games into their senior English curriculum provides a break from broad generations and allows a focus on the web of relations within which digital games exist when deployed in formal school contexts. An analytical framework which draws on three ideas emerging from postdigital studies is utilized to explore relations of power through which digital games interact as they are played and studied in schools. This analysis suggests that unitary logics about learning and digital games are insufficient and highlights the importance of engaging with the complexity, continuity and contingency in DGBL contexts to combat the hyperbole that surrounds digital games and education. Postdigital attention on actual instances of digital game deployment reveals the fragility of all knowledge claims about these technologies, contributing to a more critical discourse regarding their potential to impact school learning.
Antifouling ultrafiltration membranes based on acrylic fibers waste/nanochitosan for Congo red and crystal violet removal
Authors: Abdelhamid Ahmed E. , Selim Salah E. , Meligi Gamal A. , Hussain Ahmed I. , Mabrouk Mahmoud A. 
Published: September 2024

Abstract
In this study, acrylic fibers waste blended with different ratios of nanochitosan (0.5%, 1%, 2% and 4%, in weight) were converted into antifouling ultrafiltration nanocomposite membranes using a phase separation technique for the remediation of Congo red (CR) and crystal violet (CV) dyes from water. The fabricated nanocomposite membranes were investigated using Fourier Transform Infrared (FTIR), thermal gravimetric analysis (TGA), X-ray diffraction (XRD) and scanning electron microscope (SEM). The membrane hydrophilicity was estimated using contact angle measurements, which revealed that the 4% loaded nanochitosan had the highest hydrophilicity. Additionally, the water uptake, porosity, water contact angle and water flux of the nanocomposite membranes were assessed. The membrane filtration performances were explored for the removal of CR and CV as anionic and cationic dyes, respectively, at different concentrations and various applied pressures (1 bar to 4 bar). The experimental data revealed a high rejection (R) performance for CR (R≃100%) with a high water flux of about 150 L/(m2·h) to 183 L/(m2·h) for the optimized membrane with 2% nanochitosan at an applied pressure of 4 bar. The rejection for CV showed a variant rejection (70%–99%) at different dye concentrations with fluxes ranging from 93.6 L/(m2·h) to 149.5 L/(m2·h) for the same composite membrane. The composite membrane showed enhanced flux recovery after fouling by bovine serum albumin and was resistant to widespread gram-positive (Staphylococcus aureus) bacteria.

Graphical abstract
Adverse Childhood Experiences, Protective Factors, and Childhood Obesity: Comparing the Effectiveness of Three Resilience Frameworks
Authors: Keane Kevin , Evans Retta R. , Wilkinson Larrell L. , King Dione Moultrie , Leban Lindsay , Macrina David 
Published: September 2024

Abstract
While rates of childhood obesity continue to rise in the United States, multiple studies have linked childhood obesity to adverse childhood experiences (ACEs). ACEs researchers have begun to develop frameworks that identify protective factors that build resilience against ACEs. However, these frameworks have a limited evidence base. Utilizing data from the 2018–2020 National Survey of Children’s Health, this study compared the effectiveness of the National Scientific Council on the Developing Child (NSCDC), Health Outcomes from Positive Experiences (HOPE), and cumulative positive childhood experiences (PCEs) frameworks in mitigating the impact of ACEs on childhood obesity. Based on hierarchical logistic regression conducted on data from 46,672 children between the ages of 10 and 17 years old, this study found that both the NSCDC and HOPE frameworks were associated with childhood obesity, with each framework explaining a similar amount of variance in childhood obesity across analyses. The cumulative PCEs framework did not strengthen the association between either framework and childhood obesity. Across analyses, strong self-regulation, mastery/after-school activities, and living in a supportive neighborhood had the strongest association with childhood obesity. The findings suggest that the most salient protective factors may be those most closely associated with the direct causes of childhood obesity, with the need to identify factors across ecological levels. Future research is needed to validate these frameworks further and explore these frameworks with other outcomes. The findings have important implications for future ACEs research and ACEs interventions.

Public Relevance
By understanding which resilience frameworks and protective factors have the strongest relationship with childhood obesity among children who experienced ACEs, interventions can potentially be developed using these findings to mitigate the harmful impact of ACEs on childhood obesity.

Key Findings
This study found that the National Scientific Council on the Developing Child (NSCDC) and Health Outcomes from Positive Experiences (HOPE) frameworks were associated with childhood obesity after controlling for adverse childhood experiences (ACEs) in a sample of children between the ages of 10 and 17 years old. The strongest protective factors against childhood obesity were strong self-regulation, mastery/after-school activities, and living in a supportive neighborhood. Given the relationship between these protective factors along with several covariates in the study with childhood obesity, future ACEs interventions should potentially target these protective factors and other social determinants of health to reduce the negative impact of ACEs on childhood obesity.
External Mechanical Work Versus Energy Expenditure During on-Court Tennis Drills in Elite Adolescent Tennis Players
Authors: Swarén Mikael , Sandamas Paul , Alonso Juan , Norman Magnus , Björklund Glenn , Johansson Fredrik 
Published: September 2024

Abstract
Purpose
Tennis demands exceptional technical skills, speed, strength and endurance. Previous studies have highlighted the high energy expenditure during tennis drills due to constant directional changes. While metabolic monitoring and player tracking have been used to quantify exercise intensity and movements, mechanical efficiency (ME) in tennis remains poorly understood. This study aimed to investigate ME in tennis by combining metabolic and mechanical measurements during on-court drills.

Methods
Ten elite adolescent tennis players (males n = 5, females n = 5) performed a VO2max test on a treadmill and participated in three standard tennis drills, Spanish cross, lateral and inside out. During the tennis drill, full-body kinematics were captured, and energy expenditure was measured using a portable breath-by-breath gas analysis. ME was calculated for each drill, and individual differences were examined.

Results
Results revealed significant differences in energy expenditure and mechanical work between drills. ME was not associated with VO2max or running speed. highlighting the need to focus on other factors like strength, footwork technique, and neuromuscular training to enhance ME.

Conclusion
This study underscores the complexity of ME in tennis, with individual variations and where factors like footwork technique, muscular strength and motor abilities might influence ME.
Diversification strategies for indirect real estate. Intersection of business, economics, and society in shanghai mixed-use developments
Authors: Valero Alfonso 
Published: September 2024

AbstractThis study examines the impact of large mixed-use developments on the financial performance of publicly listed real estate firms in Shanghai from 2009 to 2019. The research uses a Multi-Criteria Decision Making (MCDM) approach, considering 14 key performance indicators (KPIs) across three categories: Corporate and Financial Information, Strategy Indicators, and Specifics of Mixed-Use Development. The article analyses the performance of large, listed investors on the Hong Kong, Shanghai, and Singapore Stock Exchanges, providing insights into their evolution over the past decade. The literature review highlights the relationship between companies’ performance and corporate finance, capital structure, and financial ratios. It identifies an existing gap in research related to mixed-use assets and indirect real estate. By using the MCDM framework, the study evaluates these assets and provides actionable insights for global investors, asset managers, and developers, helping them make informed decisions in indirect real estate investment. The findings contribute to understanding investment strategy formation in dynamic real estate markets and support informed diversification and urban policy development. This paper offers a useful appraisal framework for future MCDM risk assessments, assisting stakeholders in navigating the complexities of the real estate landscape in one of the world’s foremost metropolitan hubs. It also offers recommendations and insights on best practices for global listed firms while providing a framework for future research in the field of property investment.
Decarceration in Southern Europe: Notes on Climate Change in the Penal Field
Authors: Brandariz José A. 
Published: September 2024

AbstractAgainst the backdrop of the economic and political crises affecting Europe in the late 2000s and early 2010s, incarceration rates began to shrink in many European countries, ushering in a decarceration period that continues to this day—albeit with cross-border divergences. In fact, Europe was the world region with the greatest decline in incarceration rates in the 2010s. Evidently, this unexpected shift stands in stark contrast to the penal populism policies characterising penality in global north regions in the 1990s and 2000s, as well as to the mass incarceration path still followed by many global south jurisdictions in the 2020s. Spain is a suitable national case to examine this recent turn, since Spanish incarceration rates increased almost eightfold in just three decades, before an intriguing and steady decline began that is almost unparalleled in western Europe. This paper focuses on the Spanish case, exploring the background and proximate causes that have enabled the current decarceration scenario. In addition, it scrutinises if and to what extent the changes witnessed in the Spanish case reverberate across wider European regions. In so doing, the paper attempts to grasp the climate change impacting the penal field in many global north jurisdictions.