bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child‐Directed Speech Is Infrequent in a Forager‐Farmer Population: A Time Allocation Study
Authors: Cristia Alejandrina , Dupoux Emmanuel , Gurven Michael , Stieglitz Jonathan 
Published: November 2017

This article provides an estimation of how frequently, and from whom, children aged 0–11 years (Ns between 9 and 24) receive one‐on‐one verbal input among Tsimane forager‐horticulturalists of lowland Bolivia. Analyses of systematic daytime behavioral observations reveal < 1 min per daylight hour is spent talking to children younger than 4 years of age, which is 4 times less than estimates for others present at the same time and place. Adults provide a majority of the input at 0–3 years of age but not afterward. When integrated with previous work, these results reveal large cross‐cultural variation in the linguistic experiences provided to young children. Consideration of more diverse human populations is necessary to build generalizable theories of language acquisition.
Do Farm Support Programs Reward Production Inefficiency?
Authors: Hailu Getu , Poon Kenneth 
Published: November 2017

AbstractAgricultural policy frameworks such as Growing Forward are intended to enhance the productivity and competitiveness of the Canadian agricultural sector and to stabilize farm income. This paper examines the relationship between production efficiency and government program payments. First, we find evidence of heterogeneity in production efficiency across farms. Second, we find a negative correlation between production efficiency and the share and level of program payments. The result of this study underscores the importance of understanding the link between technical inefficiency and government payments.Les cadres stratégiques agricoles comme Cultivons l'avenir existent pour favoriser la productivité et la compétitivité du secteur agricole canadien et pour stabiliser les revenus des exploitations agricoles. Cet article examine la relation entre l'efficience de la production et les programmes gouvernementaux de paiements. En premier lieu, nous avons trouvé des preuves d'hétérogénéité dans l'efficience de la production dans toutes les exploitations agricoles. Ensuite, nous avons identifié une corrélation négative entre la production efficiente,et la part et niveau des programmes de paiements. Le résultat de cette étude met en relief l'importance de comprendre le lien entre les inefficiences techniques et les paiements gouvernementaux.
Persistent regional and racial disparities in nondirected living kidney donation
Authors: Kumar Komal , Holscher Courtenay M. , Luo Xun , Garonzik Wang Jacqueline , Anjum Saad , King Elizabeth A. , Massie Allan B. , Tonascia James M. , Purnell Tanjala S. , Segev Dorry L. 
Published: November 2017

AbstractNondirected living donors (NDLDs) are an important and growing source of kidneys to help reduce the organ shortage. In its infancy, NDLD transplantation was clustered at a few transplant centers and rarely benefited African American (AA) recipients. However, NDLDs have increased 9.4‐fold since 2000, and now are often used to initiate kidney paired donation chains. Therefore, we hypothesized that the initial geographic clustering and racial disparities may have improved. We used Scientific Registry of Transplant Recipients data to compare NDLDs and their recipients between 2008‐2015 and 2000‐2007. We found that NDLD increased an average of 12% per year, from 20 in 2000 to 188 in 2015 (IRR: 1.12, 95% CI: 1.11‐1.13, P < .001). In 2000‐2007, 18.3% of recipients of NDLD kidneys were AA; this decreased in 2008‐2015 to 15.7%. NDLD transplants initially became more evenly distributed across centers (Gini 0.91 in 2000 to Gini 0.69 in 2011), but then became more clustered at fewer transplant centers (Gini 0.75 in 2015). Despite the increased number of NDLDs, racial disparities have worsened and the center‐level distribution of NDLD transplants has narrowed in recent years.
What is a market crash?
Authors: le Bris David 
Published: November 2017

AbstractCrashes, measured as strong price decreases, are sometimes difficult to reconcile with historical events. This can be explained by the fact that a price variation will have a greater negative impact in a stable financial context than a similar variation during a highly volatile period. For example, French stocks decreased painlessly by 16 per cent in August 2002, whereas a similar fall in January 1882 led to the failure of several brokers. Market volatility was very low at the end of the nineteenth century, whereas investors are now used to dealing with large price movements. A fall of 16 per cent was much more of a shock in 1882 than it would be today. To control for the instability of the volatility, a new method for identifying crashes is proposed. Each price variation is measured in numbers of standard deviations of the preceding period. These adjusted variations can then be ranked to identify the worst market crashes. This method is tested on four long‐term series. A better match between crashes and historical events is achieved than with pure price variations. This improved matching brings new insights to several historical debates.
The left supramarginal gyrus contributes to finger positioning for object use: a neuronavigated transcranial magnetic stimulation study
Authors: Andres Michael , Pelgrims Barbara , Olivier Etienne , Vannuscorps Gilles 
Published: November 2017

AbstractIn everyday actions, we grasp dozens of different manipulable objects in ways that accommodate their functional use. Neuroimaging studies showed that grasping objects in a way that is appropriate for their use involves a left‐lateralized network including the supramarginal gyrus (SMG), the anterior intraparietal area (AIP) and the ventral premotor cortex (PMv). However, because previous works premised their conclusions on tasks requiring action execution, it has remained difficult to discriminate between the areas involved in specifying the position of fingers onto the object from those implementing the motor programme required to perform the action. To address this issue, we asked healthy participants to make judgements about pictures of manipulable objects, while repetitive transcranial magnetic stimulation (rTMS) was applied over the left SMG, AIP, PMv or, as a control, the vertex. The participants were asked to name the part of the image where the thumb or the index finger was expected to contact the object during its normal utilization or where a given attribute of the same object was located. The two tasks were strictly identical in terms of visual display, working memory demands and response requirements. Results showed that rTMS over SMG slowed down judgements of finger positions but not judgements of object attributes. Both types of judgements remained unaffected when rTMS was applied over AIP or PMv. This finding demonstrates that, within the parieto‐frontal network dedicated to object use, at least the left SMG is involved in specifying the appropriate position of the thumb and index onto the object.
A methodology for preparing a list of recommended regulated non‐quarantine pests (RNQPs)
Authors: Picard C. , Ward M. , Benko‐Beloglavec A. , Matthews‐Berry S. , Karadjova O. , Pietsch M. , Van Der Gaag D. J. 
Published: November 2017

The concept of ‘regulated non‐quarantine pest’ (RNQP) was introduced in the revised text of the FAO International Plant Protection Convention (IPPC) approved in 1997. Measures against quarantine pests (exclusion, eradication, containment) aim to prevent unacceptable economic, environmental and social impacts resulting from the introduction and/or spread of these pests. On the contrary, the concept of RNQPs is intended to prevent an unacceptable economic impact on the intended use of plants for planting by pests that are already present in the area. RNQPs have been introduced in the new EU plant health regulation, in line with available international standards. This regulation entered into force in December 2016 and will be implemented in the following 3 years. In this context, EPPO agreed to undertake a 2‐year project on RNQPs: the EU Quality Pest Project. The objective of this project was to develop a methodology and then to apply this methodology to a list of about 1400 pest–host combinations to identify which should be recommended as RNQPs.This methodology is presented in this paper, as well as the main issues discussed during its development.
Longitudinal Course and Correlates of Parents' Differential Treatment of Siblings in Mexican‐Origin Families
Authors: Padilla Jenny , McHale Susan M. , Rodríguez De Jesús Sue A. , Updegraff Kimberly A. , Umaña‐Taylor Adriana J. 
Published: November 2017

Parents' differential treatment (PDT) is a common family dynamic that has been linked to youth development and well‐being, including adjustment problems and poor sibling relationships. Much less is known, however, about the developmental course of PDT and the conditions under which parents treat their children differently in adolescence and young adulthood. This study examined longitudinal changes in mothers' and fathers' differential warmth and conflict with their two offspring from early adolescence through young adulthood and examined parents' experiences of individual stress (depressive symptoms and role overload) and marital difficulties as time‐varying correlates of (changes in) PDT. We also tested crossover effects to determine whether mothers' experiences of individual stress and marital difficulties were linked to fathers' differential treatment, and vice versa. Participants were mothers, fathers, and two siblings from 246 Mexican‐origin families who were interviewed in their homes on three occasions over 8 years. Multilevel models revealed that mothers' and fathers' differential conflict with their two children increased until middle adolescence and then declined into young adulthood, but there were no changes over time for parents' differential warmth. In general, both mothers' and fathers' levels of differential treatment were exacerbated by their own experiences of individual stress and marital difficulties and also by the experiences of their spouses. However, in some cases, greater stress than usual was linked to less differential treatment than usual.
Increased risk of cyanobacterial blooms in northern high‐latitude lakes through climate warming and phosphorus enrichment
Authors: Przytulska Anna , Bartosiewicz Maciej , Vincent Warwick F. 
Published: November 2017

Abstract

Harmful cyanobacterial blooms are an increasing problem at many locations throughout the world but are rarely reported in aquatic habitats at high latitudes. Shallow lakes are a major feature of northern permafrost landscapes and are likely to experience large‐scale changes in their limnological properties in the future as a consequence of climate warming.

In the present study, we addressed the question of what preconditions would be necessary to stimulate the growth and dominance of bloom‐forming cyanobacteria in northern fresh waters. We analysed the summer phytoplankton of 18 lakes on eroding permafrost (thaw lakes) and on glacier‐scoured rock (rock basin lakes) in subarctic Quebec, Canada, to determine their phytoplankton community structure and the biomass contribution of cyanobacteria. This survey was complemented with an incubation experiment to evaluate the direct warming and indirect phosphorus (P) enrichment effects of climate change on cyanobacterial bloom development.

All lakes contained diverse phytoplankton communities, often dominated by chrysophytes, dinoflagellates and chlorophytes. Cyanobacteria were present in all waterbodies, but their contribution to the total community biovolume was highly variable (mean of 8.7%, range 0.1%–47%). Cyanobacterial community biovolumes correlated positively with surface water temperatures, and negatively with dissolved organic carbon, soluble reactive phosphorus, iron and manganese concentrations in the surface waters.

Phosphorus enrichment of water from a thaw lake resulted in a fourfold increase of chlorophyll a (Chl‐a) and an increase in the cyanobacterial pigments echinenone and zeaxanthin. The phytoplankton counts showed that there was a sharp decrease in diversity (expressed as decline of the Shannon–Wiener index from 1.69 to 0.16), accompanied by a shift to cyanobacterial dominance, notably by the heterocystous, potentially toxic species Dolichospermum cf. planctonicum. Increased temperature led to an initial doubling of cyanobacterial biovolume, followed by the development of a chrysophyte bloom. Combined warming and P enrichment led to reduced phytoplankton biodiversity, with a community composed of cyanobacteria and chrysophytes. There was also a pronounced response by the picophytoplankton community; picocyanobacteria were strongly stimulated by P enrichment, while picoeukaryotes increased in response to warming.

The current inoculum levels of cyanobacteria in subarctic lakes and their responsiveness to temperature and phosphorus indicate the potential for an abrupt increase in their abundance, accompanied by a decrease in phytoplankton diversity. Ongoing climate change will increase the risk of noxious cyanobacterial blooms in northern lakes and ponds, with potentially negative consequences for higher trophic levels.
Landscape‐level effects on aboveground biomass of tropical forests: A conceptual framework
Authors: Melito Melina , Metzger Jean Paul , de Oliveira Alexandre A. 
Published: November 2017

AbstractDespite the general recognition that fragmentation can reduce forest biomass through edge effects, a systematic review of the literature does not reveal a clear role of edges in modulating biomass loss. Additionally, the edge effects appear to be constrained by matrix type, suggesting that landscape composition has an influence on biomass stocks. The lack of empirical evidence of pervasive edge‐related biomass losses across tropical forests highlights the necessity for a general framework linking landscape structure with aboveground biomass. Here, we propose a conceptual model in which landscape composition and configuration mediate the magnitude of edge effects and seed‐flux among forest patches, which ultimately has an influence on biomass. Our model hypothesizes that a rapid reduction of biomass can occur below a threshold of forest cover loss. Just below this threshold, we predict that changes in landscape configuration can strongly influence the patch's isolation, thus enhancing biomass loss. Moreover, we expect a synergism between landscape composition and patch attributes, where matrix type mediates the effects of edges on species decline, particularly for shade‐tolerant species. To test our conceptual framework, we propose a sampling protocol where the effects of edges, forest amount, forest isolation, fragment size, and matrix type on biomass stocks can be assessed both collectively and individually. The proposed model unifies the combined effects of landscape and patch structure on biomass into a single framework, providing a new set of main drivers of biomass loss in human‐modified landscapes. We argue that carbon trading agendas (e.g., REDD+) and carbon‐conservation initiatives must go beyond the effects of forest loss and edges on biomass, considering the whole set of effects on biomass related to changes in landscape composition and configuration.
Characteristics and outcome of prostate cancer patients with overall biopsy Gleason score 3 + 4 = 7 and highest Gleason score 3 + 4 = 7 or > 3 + 4 = 7
Authors: Verhoef Esther I , Kweldam Charlotte F , Kümmerlin Intan P , Nieboer Daan , Bangma Chris H , Incrocci Luca , van der Kwast Theodorus H , Roobol Monique J , van Leenders Geert J 
Published: November 2017

AimProstate cancer heterogeneity and multifocality might result in different Gleason scores (GS) at individual biopsy cores. According to World Health Organisation/International Society of Urologic Pathology (WHO/ISUP) guidelines, the GS in each biopsy core should be recorded with optional reporting of overall GS for the entire case. We aimed to compare the clinicopathological characteristics and outcome of men with overall biopsy GS 3 + 4 = 7 with highest GS 3 + 4 = 7 (HI = OV) to those with highest GS > 3 + 4 = 7 (HI > OV).Methods and resultsProstate cancer biopsies from the European Randomised Study of Screening for Prostate Cancer (ERSPC) were revised according to WHO/ISUP 2014 guidelines (n = 1031). In total, 370 patients had overall GS 3 + 4 = 7, 60 of whom (16%) had had at least one biopsy core with GS 4 + 3 = 7 or 4 + 4 = 8. Men with higher GS than 3 + 4 (HI > OV) in any of the cores had higher age, prostate‐specific antigen (PSA) level, number of positive biopsies, percentage tumour involvement, percentage Gleason grade 4 and cribriform or intraductal growth (all P < 0.05) than those with GS 3 + 4 = 7 at highest (HI = OV). In multivariable Cox regression analysis, including PSA, percentage positive biopsies and percentage tumour involvement, biochemical recurrence‐free survival after radical prostatectomy (P = 0.52) or radiotherapy (P = 0.35) was not statistically different between both groups.ConclusionAmong patients with overall GS 3 + 4 = 7, those with highest GS > 3 + 4 = 7 had worse clinicopathological features, but clinical outcome was not statistically significant. Therefore, the use of overall GS instead of highest GS for clinical decision‐making is justified, potentially preventing overtreatment in prostate cancer patients.
Severity and multiplicity of microvascular complications are associated with QT interval prolongation in patients with type 2 diabetes
Authors: Kobayashi Shunsuke , Nagao Mototsugu , Asai Akira , Fukuda Izumi , Oikawa Shinichi , Sugihara Hitoshi 
Published: November 2017

AbstractAims/IntroductionA prolonged QT interval plays a causal role in life‐threatening arrhythmia, and becomes a risk factor for sudden cardiac death. Here, we assessed the association between microvascular complications and the QT interval in patients with type 2 diabetes.Materials and MethodsPatients with type 2 diabetes (n = 219) admitted to Nippon Medical School Hospital (Tokyo, Japan) for glycemic control were enrolled. QT interval was measured manually in lead II on the electrocardiogram, and corrected for heart rate using Bazett's formula (QTc). Diabetic neuropathy, retinopathy and nephropathy were assessed by neuropathic symptoms or Achilles tendon reflex, ophthalmoscopy and urinary albumin excretion, respectively.ResultsIn univariate analyses, female sex (P = 0.025), duration of type 2 diabetes (P = 0.041), body mass index (P = 0.0008), systolic blood pressure (P = 0.0011) and receiving insulin therapy (P < 0.0001) were positively associated with QTc. Patients with each of the three microvascular complications had longer QTc than those without: neuropathy (P = 0.0005), retinopathy (P = 0.0019) and nephropathy (P = 0.0001). As retinopathy or nephropathy progressed, QTc became longer (P < 0.001 and P < 0.001 for trend in retinopathy and nephropathy, respectively). Furthermore, QTc was prolonged with the multiplicity of the microvascular complications (P < 0.001 for trend). Multiple regression analyses showed that neuropathy, nephropathy and the multiplicity of the microvascular complications were independently associated with QTc.ConclusionsPatients with type 2 diabetes with severe microvascular complications might be at high risk for life‐threatening arrhythmia associated with QT interval prolongation.
Epidemiology of Guillain‐Barré syndrome in Finland 2004–2014
Authors: Sipilä Jussi O.T. , Soilu‐Hänninen Merja , Ruuskanen Jori O. , Rautava Päivi , Kytö Ville 
Published: November 2017

AbstractAt total mean incidence of 0.84–1.1/100,000 the occurrence of Guillain‐Barré syndrome (GBS) is reported to be low in Finland compared to other Caucasian populations. However, a recent study from Southwestern Finland reported an incidence of 1.82/100,000 which is comparable to other Caucasian populations. We analyzed discharge data covering the years 2004 through 2014 on all neurological admissions in all Finnish university and central hospitals with a primary diagnosis of GBS. A total of 989 admissions due to GBS (917 individuals) were identified. The standardized (European population) annual incidence rate was 1.70/100,000 person‐years (95% confidence interval 1.60–1.81). GBS incidence had an increasing trend with age. The likelihood of GBS was higher among girls and adolescent women than boys and men of same age (male:female incidence rate ratio [IRR] 0.56), while in the older age groups (>19 years) the occurrence of GBS was higher among males than females (male:female IRR 1.59). The incidence of GBS remained stable during the study period. There was no seasonal variation in GBS admission frequencies (p = 0.28). No significant effect of the 2009–2010 H1N1 influenza or vaccination against it for GBS occurrence was observed. We suggest that GBS is as common, and has similar age‐distribution in Finland as in other European countries. Sex‐associated susceptibility for GBS appears to be different in children‐adolescents and adults.
Association between uterine position and transvaginal misoprostol treatment for early pregnancy failure
Authors: Chill Henry H. , Malyanker Nirit , Karavani Gilad , Haj‐Yahya Rani , Herzberg Shmuel , Bahar Raz , Shveiky David , Dior Uri P. 
Published: November 2017

AbstractAimWe aimed to determine the importance of uterine position as a predicting factor of success rate in medically treated early pregnancy failure (EPF).MethodsWe carried out a retrospective cohort study at the Obstetrics and Gynecology Department of a tertiary medical center between January 2011 and June 2012. We included women diagnosed with EPF, which we defined as women diagnosed with missed abortion up to 13 gestational weeks. Patients were treated with one or two doses of 800 μg of misoprostol vaginally in accordance with the department's protocol. Demographic, clinical, and treatment success data were collected from patient electronic records.ResultsA total of 255 women were included in our study. The success rate after treatment with misoprostol for the anterior uterine group was 78.7% as compared to the non‐anterior uterine group, which achieved a success rate of 88.1%. This difference was not statistically significant (P = 0.180). In a multivariate analysis comparing patients for whom treatment with misoprostol was successful as opposed to patients for whom treatment failed, only embryonic sac size showed a statistically significant difference, measuring shorter in the success group.ConclusionUterine position has no effect on success rate of misoprostol treatment for EPF.