bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between serum levels of calcium, parathyroid hormone and future risk of venous thromboembolism: the Tromsø study
Authors: Lerstad Gunhild , Brodin Ellen E , Svartberg Johan , Jorde Rolf , Brox Jan , Brækkan Sigrid K , Hansen John-Bjarne 
Published: March 2017

ObjectiveThe relationship between serum levels of calcium, parathyroid hormone (PTH) and risk of venous thromboembolism (VTE) has not been addressed in population-based cohorts. We investigated the associations between serum levels of calcium and PTH, with future risk of VTE in a general adult population.DesignPopulation-based cohort.MethodsA total of 27 712 subjects (25–87 years) who participated in Tromsø 4 (1994–1995) and Tromsø 5 (2001–2002) surveys were included in the study, and total calcium and PTH were measured in 27 685 and 8547 subjects respectively. Incident VTE was recorded through December 31, 2012. Cox-regression models with calcium and PTH as time-varying exposures were used to calculate hazard ratios (HR) of VTE by quartiles of calcium and PTH. Quartiles of calcium and PTH were also combined to assess the effect of discordants of both PTH and calcium (e.g. highest and lowest quartiles of both calcium and PTH) on VTE risk using the middle two quartiles as reference.ResultsThere were 712 VTEs during 15.0 years of median follow-up. Serum levels of calcium and PTH were not associated with risk of VTE. However, subjects with discordant high serum levels of both calcium and PTH (calcium ≥2.45 mmol/L and PTH ≥4.0 pmol/L) had increased risk of VTE compared to those in subjects with normal calcium and PTH (multivariable HR: 1.78, 95% CI: 1.12–2.84).ConclusionsSerum levels of calcium and PTH separately were not associated with future risk of VTE, but subjects with high levels of both calcium and PTH had increased risk of VTE compared to those in subjects with normal levels.
Changes in the management and comorbidities of acromegaly over three decades: the French Acromegaly Registry
Authors: Maione Luigi , Brue Thierry , Beckers Albert , Delemer Brigitte , Petrossians Patrick , Borson-Chazot Françoise , Chabre Olivier , François Patrick , Bertherat Jérôme , Cortet-Rudelli Christine , Chanson Philippe , _ _ 
Published: March 2017

ContextAcromegaly is a rare disease associated with chronic multisystem complications. National registries have been created in several countries.DesignThe French Registry contains data on acromegaly epidemiology, management and comorbidities recorded over more than three decades, retrospectively until 1999 and prospectively from 1999 to 2012.ResultsData could be analyzed for 999 of the 1034 patients included in the registry (46% males). Disease control, defined as IGF-I normalization (adjusted for age and sex), was achieved in 75% of patients at the last follow-up visit. Half the patients with uncontrolled disease had IGF-I levels below 1.5 times the upper limit of normal (ULN). The proportion of patients with surgically cured disease did not change markedly over time, whereas the proportion of patients with uncontrolled disease fell and the proportion of patients with medically controlled disease rose. Cardiovascular, metabolic, respiratory and rheumatologic comorbidities and their outcomes were recorded for most patients, and no noteworthy overall deterioration was noted over time. Cancer occurred in 10% of patients, for a standardized incidence ratio of 1.34 (95% CI: 0.94–1.87) in men and 1.24 (0.77–1.73) in women. Forty-one patients died during follow-up, for a standardized mortality ratio of 1.05 (0.70–1.42). Most deaths were due to cancer.ConclusionsThe majority of patients with acromegaly now have successful disease control thanks to the multistep management. The incidence of comorbidities following diagnosis of acromegaly is very low. Life expectancy is now close to that of the general population, probably owing to better management of the GH/IGF-I excess and comorbidities.
Massive Pulmonary Embolism Treated with Catheter Therapy and Extracorporeal Membrane Oxygenation
Authors: Teman Nicholas R , Xiao Jianzhou T. , Tribble Curtis G 
Published: March 2017

Massive pulmonary embolism (PE) is associated with significant morbidity and mortality. Treatment for massive PE can include systemic thrombolysis and catheter-directed therapy. We present the case of a patient with massive PE successfully treated with catheter-directed therapy, using extracorporeal membrane oxygenation for hemodynamic support, and discuss some of the potential complications associated with this therapy.
Screening of a Small Spherical Macroion by Oppositely Charged Flexible Polyelectrolyte
Authors: Quyen Vu Van , Yen Vu Thi Hai , Toan Nguyen The 
Published: March 2017

Electrostatic interactions play important roles in the assembly, the structureand the functions of many biological as well as soft matter systems. In the presence of a macro-ion in aqueous solution, oppositely charged molecules mobilize around it to screen out its electrostatic potential. In this paper, we focus on screening of small macroion by a flexible polyelectrolyteusing Monte-Carlo simulation. It is shown that the condensation of the polyelectrolyte around the macroion shows a first order phase transition from a dense to a dilute concentration of monomers. The width of the condensed region increases with stronger screening or with smaller macro-ion charges. For small macro-ion charge, or when the Coulomb interactions are strongly screened, no complexation between the polyelectrolyte and the macro-ion happens.Additionally, long polyelectrolyte protrudes both tails and loops from the macroion. This is quite different from the case of large macroions where only tails appear. Our results can be used to explain various experimental trends.
The 3-3-1 Model with Arbitrarily Charged Leptons
Authors: Long Hoang Ngoc , Loi Duong Van , Thao Nguyen Chi , Giang Thanh Huu Hong 
Published: March 2017

The gauge model based on \(\mathrm{SU}(3)_C\otimes \mathrm{SU}(3)_L\otimes \mathrm{U}(1)_X\) group with arbitrarily electric charged exotic leptons is presented. The mass eigenvalues and eigenstates for neutral gauge bosons are presented in the general form. We show that in the 3-3-1 models, there always exists triple Higgs self-coupling. The lepton number operator is also presented.
Chemical Oxygen Demand Analysis of Anaerobic Digester Contents
Authors: Harnadek Colin M. W. , Guilford Nigel G.H. , Edwards Elizabeth A. 
Published: March 2017

An anaerobic digester converts organic materials into biogas and digestate in the absence of oxygen. The organic materials studied in this experiment include fibres (types of paper or cardboard), food waste, and woodchips, which serve as a bulking agent. To analyze digester performance, it is necessary to calculate an accurate mass balance based on the chemical oxygen demand (COD) entering and exiting the system. Digester performance refers to maximum efficiency and biogas yield. The COD of the biogas is known, but that of the feed and the digestate is not. This paper describes a method for measuring the COD of the feed materials and the digestate by creating representative aqueous suspensions of each. The challenges are to ensure that the suspensions are representative of the feed or digestate, and that samples of the suspension extracted for COD analysis are consistent and reproducible. To obtain an accurate COD measurement of the feed and digestate samples, a specific procedure was developed: each material was processed in a blender with deionized water, creating a pulp from which samples were pipetted during continuous mixing of the suspension. The conducted trials provided COD content values ranging from 1.27-1.59 g of COD/ g of dry feed, depending on the fibre. Standard deviations of the COD content ranged from 2.8% to 12.7%, indicating that the procedure is reliable and the results precise. The measured COD content values allow an accurate mass balance of the digester to be determined, ultimately providing a better understanding of the system as the total digestible material entering the digester will be known. An accurate mass balance can improve the efficiency of the digester in order to produce optimal quantities of biogas. The biogas can be harnessed into energy from otherwise useless waste. Further study in this topic can explore the COD content of wider ranges of organic solids as well as further optimize the procedure in order to provide even more accurate results.
Evaluation of Hydrogen-Oxygen Recombiner Catalysts Under Various Conditions for Nuclear and Non-Nuclear Hydrogen Safety
Authors: Qin Helen 
Published: March 2017

Hydrogen plays an important role in nuclear and non-nuclear safety, as the unsafe manipulation of hydrogen can lead to dangerous accidents. This concern has led the Hydrogen Isotopes Technology Branch at the Canadian Nuclear Laboratories to develop catalysts in order to aid in the recombination of hydrogen and oxygen. This research project evaluates catalysts with different compositions under various conditions (i.e. dry, humid) in a spinning basket reactor (SBR). Results suggest that catalysts with lower wetproof coating loading have higher activity levels after being exposed to water vapour or immersed in liquid water compared to catalysts with higher amounts of wetproof coating. The specific activity levels were 1.91 cm3 H2/s·gCAT and 1.57 cm3 H2/s·gCAT, normalized to the benchmark catalyst’s activity in humid conditions, for catalysts with low and high amounts of wetproof coating, respectively. Normalization was performed so that the activity levels of the benchmark catalyst in humid conditions was equal to one, thus assigning the other activity level values based on their relation to the benchmark catalyst’s activity levels in humid conditions. For the benchmark catalyst, activity levels in water vapour and immersion conditions were about the same, whereas activity levels for the newly developed catalysts (with low and high wetproofing agent loadings) varied depending on the water exposure levels of the test. Thus, despite the wetproofing, the amount of water exposure had an effect on catalyst activity levels. This trend demonstrates that the benchmark catalyst was well wetproofed and suggests that further improvement is needed in the wetproofing method used for the new catalyst.
Programa Nacional de Habitação Rural e modo de morar no campo: reflexões a partir da casa rural na Zona da Mata mineira
Authors: Carvalho Aline Werneck Barbosa de , Paula Nayara Elisa Silva de , Pereira Dafhini Aline Grego 
Published: March 2017

O Programa Nacional de Habitação Rural (PNHR) constitui a vertente rural do Programa Minha Casa, Minha Vida - MCMV e tem como objetivo reduzir o déficit habitacional rural por meio da reforma ou construção de novas moradias. Apesar da importância desse Programa para a fixação do homem ao campo, neste artigo procura-se chamar a atenção para a necessidade de adequação da tipologia de casa do PNHR ao modo de morar na área rural. A pesquisa fundamentou-se na análise da habitação rural em Minas Gerais, mais especificamente na região da Zona da Mata, bem como na análise da legislação que rege o PNHR, como leis, portarias e decretos. Os resultados apontaram que as especificações técnicas mínimas estabelecidas pelo Ministério das Cidades para o PNHR desconsideram o modo de vida rural e os hábitos dos moradores. Embora haja o cuidado de não estabelecer áreas mínimas para os compartimentos, a fixação da área útil total em 36m2 e o dimensionamento induzido a partir do tamanho e descrição do mobiliário mínimo conduzem à formatação de um programa de necessidades muito semelhante ao da tipologia de casa adotado pela versão urbana do Programa Minha Casa Minha Vida.
Projeto de assentamento Maisa: conflito entre os saberes técnico e popular no processo de planejamento físico-espacial do seu habitat
Authors: Cerqueira Maria Cândida Teixeira de 
Published: March 2017

Como o arquiteto e urbanista pode assimilar conhecimentos e aprimorar sua prática profissional a partir da vivência de situações em conflito existente entre o seu saber técnico e o saber popular no mundo rural? Este artigo relata o envolvimento deste profissional no planejamento e concepção do espaço dos habitats do assentamento Maisa (19.702 ha), remanescente de grande empresa fruticultora do RN. Corresponde a uma experiência pioneira no país, visto que pela primeira vez, uma instituição de assessoria técnica (AESCA) a movimento social (MST) contrata, de maneira legalizada - com aval do Estado, através do INCRA - profissional da arquitetura e urbanismo, introduzindo novos saberes. Assim, durante o ano de 2005, através de metodologia participativa, a equipe técnica, lideranças e assentados, coordenados pelo MST, conceberam o projeto dos habitats (denominados agrovilas pelo INCRA) Pomar, Apodi, Real e Montana. Foram experienciados conflitos quanto a: localização dos habitats; dimensão dos lotes de moradia; modelo da habitação; modo de construção (mutirão ou contratação de empreiteiras). Apreende-se que as decisões finais devem ser fruto da avaliação coletiva dos limites entre o saber popular e as necessidades técnicas, entendendo os momentos de ruptura e de dominação, para deles tirar partido.
ПОНАВЉАЊА КАО ОСНОВ ЗНАЧЕЊА У ПЕСМИ „ЗИДАЊЕ СКАДРА”
Authors: Пешикан-Љуштановић Љиљана Ж. 
Published: March 2017

Рад се бави понављањима у песми Старца Рашка Зидање Скадра, то оним везаним за градњу, градбену жртву, породичне односе, мајчинство, на којима почива значење песме. Показује се да је песма компонована на принципу понављања: од стиха, преко појединих сегмената, до целине дела. Претпоставља се да овакав тип анализе може олакшати посредовање ове песме ученицима и њихово разумевање концепата традиционалне културе.
Pemotongan Sapi Betina Produktif di Rumah Potong Hewan di Daerah Istimewa Yogyakarta
Authors: Rasminati Nur 
Published: March 2017

<div class="WordSection1"><p><em>The research was conducted to know the number of the productive female beef cattle slaughtering at abattoir in DIY. All of the beef cattle which slaughtered along a month were used in this research. The result showed that the number of productive beef cattle slaughtered up to 2 years old were 28.98%; 2 – 5 years old were 69.55%; more than 5 years old were 1.44%. The female beef cattle slaughtered were 54.58% and the male beef cattle slaughtered were 32.36%. The non productive beef cattle slaughtered were 13.04% including 5.79% male and 7.24% female. The Peranakan Ongole (PO) breed slaughtered was 60.36% (125 heads), Brahman Cross 16.42% (34 heads), Simmental 15.94% (33 heads), Brangus 2.42% (5 heads), Limousine 4.35% (9 heads) and PFH 0.48% (1 heads). The percentage of productive beef cattle slaughtering were 86.95% with female beef productive were 64.25% and the PO breed at 2 – 5 years old were the most slaughtered. It could be concluded that the productive female beef cattle slaughtering at abattoir in DIY was quite high, which may influence the breed resources of beef cattle.</em></p><p><em> </em></p><p><em>Key words : Productive beef cattle, slaughtering, abattoir, Yogyakarta</em></p></div><em><br clear="all" /> </em>
Evaluasi Biofermentasi Rumen Sapi Peranakan Ongole yang Diberi Pakan Berserat
Authors: Suprayogi Wara Pratitis Sabar 
Published: March 2017

<p><em>The experiment was conducted to evaluat</em><em>e the nutritional value of ground peanut straw, king grass and corn forage </em><em>and their ability </em><em>to provid</em><em>e nutrients for livestock in terms of rumen fermentation. Three rumen</em><em>-fistulated </em><em>PO </em><em>cattles were used </em><em>to investigate rumen fermentation parameter (pH,</em><em> NH<sub>3,</sub></em><em>VFA). The cattle</em><em>s were fed ground peanut straw (PS), king grass (KG) and corn forage (CF) ad libitum as single f</em><em>eed. The values of rumen fermentation parameters were analy</em><em>zed using</em><em> Analysis of Variance of Completely </em><em>Randomized Design.</em><em> The result showed that rumen pH,</em><em> and of cattle fed with PS,</em><em> KG and CF were 6.94, 6.68 and 6.71</em><em>, NH<sub>3</sub> </em><em>concentrations 13.71, 6.85 and 4.37mg/100ml</em><em>, and total VFA concentrations 48.99, 70.17 and 51.59 mmol/l, respectively. Values of pH and NH<sub>3</sub> concentration were significantly different (p&lt;0.05) among </em><em>treatments, meanwhile VFA concentration were not significantly different. Ground peanut straw </em><em>resulted the highest rumen fermentation parameters.</em></p><p><em> </em></p><p><strong><em>Key </em></strong><strong><em>words</em></strong><em> : </em><em>Peranakan Onggole cattle, </em><em>fibrous </em><em>feed, </em><em>nutritive value, rumen </em><em>fermentation </em></p>
Evaluasi Adopsi Inovasi Feed Additive Herbal untuk Ternak Ayam Pedaging
Authors: Sari Ayu Intan 
Published: March 2017

<p><em>The purpose of this research is to evaluate technically and economical adoption of herbal feed additive innovation for broiler. </em><em>This research was conducted from August to October 2008, in the broiler farm at Karanganyar, Sragen, and Boyolali by using research based method of descriptive analysis. The respondents of the research were 34 farmers selected by using purposive convenience sampling</em><em>. </em><em>Evaluation technical adoption of herbal feed additive innovation, was analyzes base on the respondent’s answer to questionnaire which draw a process adoption of innovation, consist of the first reason of farmer apply innovation, process receiving innovation and the difficulties and in apply innovation. The result of research shows based on technical evaluation result there differences adoption innovation process on adopter category early and late, it is first reason receive innovation where on early adopter category because on broiler production higher (52,94%), while the first reason for late adopter category in receive innovation because to save production cost (47,06%). The result also shows that early adopter category of farmers (58,82%) not found difficulties in apply innovation feed additive, while in late category adopter (52,94%) . Found difficulties in apply innovation feed additive. Base on economic evaluation value, the income of broilers farm without using feed additive herbal at scale <span style="text-decoration: underline;">&gt;</span> 8.000 broiler Rp 2.392,18 per broiler, scale 3001– 8.000 broilers Rp 1.910,54 per broiler, and the income at scale <span style="text-decoration: underline;">&lt;</span> 3000 broilers Rp 1.616,59 per broiler. Income of broilers farm with using feed additive herbal base on scale <span style="text-decoration: underline;">&gt;</span> 8.000 broilers Rp 2.557,19 per broiler, scale 3001- 8000 broilers Rp 1.767,15 per broiler. The conclusion from this research are different evaluation score technical adoption innovation feed additive herbal at the early and late adopter category, it is on the first reason in receive innovation where the early adopter category because of the broilers productivity higher, while late adopter category in receive innovation because the save the production cost. Base on economic evaluation result, there is increase income received by farmers after using innovation feed additive herbal and more scale broilers farm, so the advantage which get also bigger.</em></p><p><em> </em></p><strong><em>Key words</em></strong><em>: Technical evaluation, economic evaluation, adoption invation, herbal feed additive</em>
Potential Financial Conflict of Interest Among Physician Editorial Board Members of Orthopaedic Surgery Journals
Authors: Mehlman Charles T. , Okike Kanu , Bhandari Mohit , Kocher Mininder S. 
Published: March 2017

Background:
The practice of medicine is based on evidence from peer-reviewed literature. As can occur with author-related funding, the integrity of the process by which manuscripts are reviewed, edited, and approved for publication may be at risk due to financial conflict of interest. The purpose of our study was to assess potential financial conflict of interest among physician editorial board members of orthopaedic surgery journals.

Methods:
We identified the physician editorial board members of 15 orthopaedic surgery journals and searched the 2014 payments that were archived in the Centers for Medicare & Medicaid Services Open Payments system (mandated by the Physician Payments Sunshine Act). Total dollar values were calculated and tabulated in a multilevel fashion: nothing reported, >$0 and ≤$10,000, >$10,000, >$250,000, and >$950,000.

Results:
We identified 908 physician editors of 15 orthopaedic surgery journals. Something of financial value was received by 78% (712 of 908) of these individuals. Rates of editorial board potential financial conflict of interest for individual journals ranged from 4% to 73% in the >$10,000 category. At the >$250,000 mark, rates ranged from 0% (2 journals) to 31%. When applying the >$950,000 criterion, physician potential conflict of interest ranged from 0% (5 journals) to 13%.

Conclusions:
Editor-related potential financial conflicts of interest exist in the orthopaedic surgery journals that we analyzed. These potential financial conflicts could possibly impact reviews.
Role of Weekly Teriparatide Administration in Osseous Union Enhancement within Six Months After Posterior or Transforaminal Lumbar Interbody Fusion for Osteoporosis-Associated Lumbar Degenerative Disorders
Authors: Ebata Shigeto , Takahashi Jun , Hasegawa Tomohiko , Mukaiyama Keijiro , Isogai Yukihiro , Ohba Tetsuro , Shibata Yosuke , Ojima Toshiyuki , Yamagata Zentaro , Matsuyama Yukihiro , Haro Hirotaka 
Published: March 2017

Background:
For elderly patients, posterior lumbar interbody fusion (PLIF) or transforaminal lumbar interbody fusion (TLIF) is usually performed to treat lumbar degenerative diseases. However, some patients exhibit pseudarthrosis following such procedures. The anabolic agent teriparatide is an approved treatment for promoting bone formation in osteoporotic patients. Our multicenter, prospective randomized study assessed the role of once-weekly teriparatide administration on patient outcomes following interbody fusion.

Methods:
Patients were females who were ≥50 years of age, had a bone mineral density (BMD) of <80% of the sex-matched young adult mean and/or previous spinal compression or femoral fractures, and had lumbar degenerative disease. Patients were randomly allocated to receive either weekly teriparatide, administered subcutaneously starting at week 1, for 6 months postoperatively (the teriparatide arm), or no teriparatide (the control arm). Blinded radiographic evaluations were performed using dynamic radiography and computed tomography (CT) and assessed by modified intention-to-treat analysis and per-protocol analysis. Clinical and neurological symptoms were evaluated using the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOA-BPEQ) and the Oswestry Disability Index (ODI).

Results:
Seventy-five patients were randomized to treatment, and 66 patients completed treatment. At 4 months postoperatively, bone fusion in the 2 center CT slices was significantly higher in the teriparatide arm compared with the control arm in the age-adjusted modified intention-to-treat analysis and was significantly higher at 6 months in the per-protocol analysis. Radiographic examinations showed no disc-space narrowing and no intervertebral disc instability. JOA-BPEQ and ODI results were improved postoperatively in both treatment arms.

Conclusions:
Weekly administration of teriparatide promoted bone formation at the surgical fusion site and decreased bone resorption, as indicated by bone metabolic marker results, within the early postoperative period. Our findings suggest that combining lumbar interbody fusion and teriparatide treatment may be an effective option for managing lumbar degenerative disease in elderly patients.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.