bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: HERSTELLUNG VERSCHIEDENER AKTIVIERTER ESTER VON TRIPEPTIDEN, DIE ALS MONOMERE ZUR GEWINNUNG VON MODELLEN MIT KOLLAGEN‐STRUKTUR DIENEN
Authors: SIBNEV V. A. , CUVAEVA T. P. , POROSIN K. T. 
Published: February 2016

AbstractPolychlorphenyl‐ oder Nitrophenyl‐succinimidester von N‐Carbobenzoxyaminosäuren (Glycin, Hydroxyprolin) werden entweder durch Einwirkung der Phenole in Chloroform bei ‐10°C unter Zugabe von Phosphoroxychlorid in Pyridin oder durch Zugabe des Phenols bei ‐15°C zur Carbobenzoxy‐aminosäure hergestellt, nachdem diese vorher mit Triäthylamin und Isobutylchlorformiat vorbehandelt wurde (Ausbeute 77 ‐ 98%).
ChemInform Abstract: VERWENDUNG DER N‐HYDROXY‐SUCCINIMID‐ESTER FUER DIE HERST. VON MODELLEN MIT KOLLAGEN‐STRUKTUR
Authors: SIBNEV V. A. , CUVAEVA T. P. , MARTYNOVA G. A. , POROSIN K. T. 
Published: February 2016

AbstractDen N‐Hydroxy‐succinimidester eines Carboxy‐tripeptids (Glycin‐Prolin‐Leucin, Glycin‐Prolin‐Alanin, Glycin‐Prolin‐Glycin) erhält man, indem dem Carbobenzoxy‐tripeptid in Dimethylformamid Dicyclohexylamin und N‐Hydroxy‐succinimid zugesetzt werden (Ausbeute 50 ‐ 80%).
ChemInform Abstract: PEPTIDSYNTH. 42. MITT. VERGLEICH EINIGER KUPPLUNGSMETHODEN
Authors: BIRR CHRISTIAN , LOCHINGER WERNER , WIELAND THEODOR 
Published: February 2016

AbstractDie schwierig zu verknüpfenden Peptidkomponenten (I) und (II) wurden nach verschiedenen Methoden zum Dipeptid (III) umgesetzt.
ChemInform Abstract: AMINOACYLDERIVATE VON NUCLEOSIDEN, NUCLEOTIDEN UND POLYNUCLEOTIDEN 8. MITT. DARST. VON 2′(3′)‐O‐L‐PHENYLALANYLURIDIN, ‐CYTIDIN, ‐ADENOSIN‐, INOSIN,‐GUANOSIN UND 2′‐DESOXY‐3′‐O‐L‐PHENYLALANYLADENOSIN
Authors: ZEMLICKA J. , CHLADEK S. , HALADOVA Z. , RYCHLIK I. 
Published: February 2016

AbstractDie Reaktion der Tritylribonucleoside (Ia) bis (Ic) mit dem Anhydrid (II) in Pyridin liefert bei nachfolgender Detritylierung und im Falle von Cytidin und Adenosin bei zusätzlicher Dimethylaminomethylenabspaltung die Ribonucleosidgemische (IIIa) bis (IIIc) und (IVa) bis (IVc) (23‐52% Ausbeute).
ChemInform Abstract: OLIGONUCLEOTID‐VERBINDUNGEN 35. MITT. RK. VON DIRIBONUCLEOSIDPHOSPHATEN MIT DIMETHYLFORMAMIDACETALEN
Authors: HOLY A. , ZEMLICKA J. 
Published: February 2016

AbstractDurch Dimethylformamiddimethylacetal werden die Ammonium‐ bzw. Triäthylammoniumsalze der Diribonucleosidphosphate (I) bei 60‐80°C zu den entsprechenden N‐3‐ bzw. N‐1‐Methylderivaten methyliert.
ChemInform Abstract: UBICHINONE UND VERWANDTE SUBSTANZEN 13. MITT. EPOXY‐UBICHINONE
Authors: MORIMOTO HIROSHI , IMADA ISUKE , WATANABE MASAZUMI , NAKAO YOSHIO 
Published: February 2016

AbstractDie Ubichinone (Ia), (Ib), (IIa) und (IIb) werden aus Pseudomonas alkanolytica isoliert und identifiziert.
ChemInform Abstract: UBICHINONE UND VERWANDTE SUBSTANZEN 14. MITT. UMSETZUNG VON UBICHROMENOL‐6 MIT NATRIUM IN AETHANOL
Authors: MORIMOTO HIROSHI , IMADA ISUKE , GOTO GIICHI 
Published: February 2016

AbstractAus dem trans‐Ubichinon (I) wird basisch das Chromenol (II) gewonnen, das mit Na/Äthanol das Chromanol (III) (Ausbeute 40%) neben den Ubichinonen (IVa) (17%), (IVb) (1,2%), (IVc) (1,3%), (Va) (15%), (Vb) (2,6%) und (Vc) (1,8%) liefert.
ChemInform Abstract: ANALOGA DER COFERMENTE FUER KOHLENHYDRATSTOFFWECHSEL 12. MITT. HERSTELLUNG DER N6‐METHYL‐ADENOSIN‐DIPHOSPHAT‐GLUCOSE UND N6,N6‐DIMETHYL‐ADENOSINDIPHOSPHAT‐GLUCOSE
Authors: KOCETKOV N. K. , BUDOVSKIJ E. I. , SIBAEV V. N. , SPIRIDONOVA S. M. 
Published: February 2016

AbstractAus dem Dinatrium‐Salz des 5′‐Monophosphats der Adenin‐glucose (I) wird mit Dimethylphosphat das N1‐Methyl‐adenosin‐5′‐phosphat (II) erhalten (Ausbeute 85%), das in ammoniakalischer Lösung bei 40°C zum N6‐Methylamin‐9β‐D‐ribofuranosyl‐purin‐5′‐phosphat (II) umgelagert wird (Ausbeute 59%).
ChemInform Abstract: DARST. UND BIOAKTIVITAET VON LINCOMYCIN‐2‐PHOSPHAT
Authors: MOROZOWICH W. , LAMB D. J. , KARNES H. A. , MACKELLAR F. A. , LEWIS C. , STERN K. F. , ROWE E. L. 
Published: February 2016

Abstract3,4‐O‐Anisyliden‐lincomycin (I) und Tritylchlorid (II) reagieren in Aceton in Gegenwart von Triäthylamin zum 7‐O‐Trityl‐Derivat (IIIa) (72% Ausbeute), das mit Benzoylchlorid in einem Pyridin‐Chloroform‐Gemisch zu (IIIb) verestert wird.
Adolescent weight and height are predictors of specific non‐Hodgkin lymphoma subtypes among a cohort of 2,352,988 individuals aged 16 to 19 years
Authors: Leiba Merav , Leiba Adi , Keinan‐Boker Lital , Avigdor Abraham , Derazne Estela , Levine Hagai , Kark Jeremy D. 
Published: February 2016

BACKGROUNDThe age‐adjusted annual incidence of non‐Hodgkin lymphoma (NHL) has risen worldwide. This trend may be affected by the secular increase in height and the sharp upswing in adolescent overweight; these drive increased insulinlike growth factor 1 and chronic inflammation, which may play an etiologic role. This study examined the association of the body mass index (BMI) and height of adolescents with NHL subtypes, which have been insufficiently evaluated.METHODSHealth‐related data on 2,352,988 Israeli adolescents, aged 16 to 19 years, who were examined between 1967 and 2011 were linked to the Israel National Cancer Registry to derive the NHL incidence up to December 31, 2012 (4021 cases). Cox proportional hazards modeling was used to estimate the multivariate‐adjusted hazard ratio (HR) for NHL subtypes associated with the BMI and height of adolescents.RESULTSAdolescent overweight and obesity were associated with an HR of 1.25 (95% confidence interval [CI], 1.13‐1.37; P = 1.14 × 10−5) for NHL in comparison with normal weight. There was a graded association of height with NHL (P = 4.29 × 10−9), with the tallest adolescents (≥95th percentile vs 25th to < 50th percentiles [US Centers for Disease Control and Prevention]) exhibiting an HR of 1.28 (95% CI, 1.04‐1.56). Marginal zone lymphoma, primary cutaneous lymphoma (PCL), and diffuse large B‐cell lymphoma (DLBCL) showed the strongest associations for overweight/obesity, and DLBCL and PCL showed the strongest associations for height.CONCLUSIONSThe findings of this large cohort study add to the growing body of evidence showing that higher body weight and taller stature during adolescence are associated with an increased risk of NHL and may modestly contribute to its increasing incidence. Further studies are needed to elucidate the mechanisms linking anthropometric measures and NHL risk. Cancer 2016;122:1068–1077. © 2016 American Cancer Society
Epigenetic Treatment of Neuropsychiatric Disorders: Autism and Schizophrenia
Authors: Moos Walter H. , Maneta Eleni , Pinkert Carl A. , Irwin Michael H. , Hoffman Michelle E. , Faller Douglas V. , Steliou Kosta 
Published: February 2016

ABSTRACT

Preclinical Research

Neuropsychiatric disorders are a heterogeneous group of conditions that often share underlying mitochondrial dysfunction and biological pathways implicated in their pathogenesis, progression, and treatment. To date, these disorders have proven notoriously resistant to molecular‐targeted therapies, and clinical options are relegated to interventional types, which do not address the core symptoms of the disease. In this review, we discuss emerging epigenetic‐driven approaches using novel acylcarnitine esters (carnitinoids) that act on master regulators of antioxidant and cytoprotective genes and mitophagic pathways. These carnitinoids are actively transported, mitochondria‐localizing, biomimetic coenzyme A surrogates of short‐chain fatty acids, which inhibit histone deacetylase and may reinvigorate synaptic plasticity and protect against neuronal damage. We outline these neuroprotective effects in the context of treatment of neuropsychiatric disorders such as autism spectrum disorder and schizophrenia. Drug Dev Res 77 : 53–72, 2016.   © 2016 Wiley Periodicals, Inc.
A sensorimotor area in the songbird brain is required for production of vocalizations in the song learning period of development
Authors: Piristine Hande C. , Choetso Tenzin , Gobes Sharon M. H. 
Published: February 2016

ABSTRACTSensory feedback is essential for acquiring and maintaining complex motor behaviors, including birdsong. In zebra finches, auditory feedback reaches the song control circuits primarily through the nucleus interfacialis nidopalii (Nif), which provides excitatory input to HVC (proper name)—a premotor region essential for the production of learned vocalizations. Despite being one of the major inputs to the song control pathway, the role of Nif in generating vocalizations is not well understood. To address this, we transiently inactivated Nif in late juvenile zebra finches. Upon Nif inactivation (in both hemispheres or on one side only), birds went from singing stereotyped zebra finch song to uttering highly variable and unstructured vocalizations resembling sub‐song, an early juvenile song form driven by a basal ganglia circuit. Simultaneously inactivating Nif and LMAN (lateral magnocellular nucleus of the anterior nidopallium), the output nucleus of a basal ganglia circuit, inhibited song production altogether. These results suggest that Nif is required for generating the premotor drive for song. Permanent Nif lesions, in contrast, have only transient effects on vocal production, with song recovering within a day. The sensorimotor nucleus Nif thus produces a premotor drive to the motor pathway that is acutely required for generating learned vocalizations, but once permanently removed, the song system can compensate for its absence. © 2016 Wiley Periodicals, Inc. Develop Neurobiol 76: 1213–1225, 2016
Confronting species distribution model predictions with species functional traits
Authors: Wittmann Marion E. , Barnes Matthew A. , Jerde Christopher L. , Jones Lisa A. , Lodge David M. 
Published: February 2016

AbstractSpecies distribution models are valuable tools in studies of biogeography, ecology, and climate change and have been used to inform conservation and ecosystem management. However, species distribution models typically incorporate only climatic variables and species presence data. Model development or validation rarely considers functional components of species traits or other types of biological data. We implemented a species distribution model (Maxent) to predict global climate habitat suitability for Grass Carp (Ctenopharyngodon idella). We then tested the relationship between the degree of climate habitat suitability predicted by Maxent and the individual growth rates of both wild (N = 17) and stocked (N = 51) Grass Carp populations using correlation analysis. The Grass Carp Maxent model accurately reflected the global occurrence data (AUC = 0.904). Observations of Grass Carp growth rate covered six continents and ranged from 0.19 to 20.1 g day−1. Species distribution model predictions were correlated (r = 0.5, 95%CI(0.03, 0.79)) with observed growth rates for wild Grass Carp populations but were not correlated (r = −0.26, 95%CI(−0.5, 0.012)) with stocked populations. Further, a review of the literature indicates that the few studies for other species that have previously assessed the relationship between the degree of predicted climate habitat suitability and species functional traits have also discovered significant relationships. Thus, species distribution models may provide inferences beyond just where a species may occur, providing a useful tool to understand the linkage between species distributions and underlying biological mechanisms.
Synthesis of Vanadium‐Incorporated, Polyoxometalate‐Based Open Frameworks and Their Applications for Cathode‐Active Materials
Authors: Zhang Zhenxin , Yoshikawa Hirofumi , Zhang Zhongyue , Murayama Toru , Sadakane Masahiro , Inoue Yasunori , Ueda Wataru , Awaga Kunio , Hara Michikazu 
Published: February 2016

AbstractThe tuning of the chemical composition of polyoxometalate (POM)‐based open framework materials with the same structure, leading to a property change of the materials, is interesting. Here, we report the synthesis of a series of vanadium‐incorporated, ϵ‐Keggin polyoxometalate‐based open framework materials by using a hydrothermal method. The resulting materials were characterized by powder X‐ray diffraction, FTIR spectroscopy, scanning electron microscopy, energy dispersive X‐ray spectroscopy, X‐ray photoelectron spectroscopy, and elemental analysis. Our results indicate that V is successfully incorporated into the frameworks of the materials. The introduced amount of V can be adjusted by controlling the addition of the precursor V compounds. The performances of these materials as cathode materials for Li‐ion batteries have been tested. Incorporation of V can improve the cycle performance. After the 20th cycle of the charge–discharge process, the materials were transformed to the Li2MoO4 phase.
RhIII‐Catalyzed C–H Allylation of Amides and Domino Cycling Synthesis of 3,4‐Dihydroisoquinolin‐1(2H)‐ones with N‐Bromosuccinimide
Authors: Dai Huimin , Yu Chao , Lu Changsheng , Yan Hong 
Published: February 2016

AbstractA RhIII‐catalyzed C–H allylation of electron‐deficient arenes, heteroarenes, and alkenes at room temperature was developed with allyl bromide. The reaction was carried out in diethyl ether without dehydration, and C–H activation was assisted by the directing anionic nitrogen of the aniline‐derived amide. Following the allylation, a domino cycling synthesis of 3,4‐dihydroisoquinolin‐1(2H)‐ones with N‐bromosuccinimide (NBS) through intramolecular aminobromination of the introduced double bond was achieved.
Secrecy performance of MIMO Nakagami‐m wiretap channels with optimal TAS and different antenna schemes
Authors: da Costa Daniel Benevides , Ferdinand Nuwan Suresh , Dias Ugo Silva , de Sousa Rafael Timóteo , Latva‐aho Matti 
Published: February 2016

AbstractTransmit antenna selection (TAS) in wiretap channels has arisen as a simple promising scheme to improve physical layer security. However, up to now, TAS schemes have aimed at maximising the instantaneous signal‐to‐noise ratio of the legitimate receiver, which by its essence is a sub‐optimal strategy from a secrecy point of view. In this paper, unlike previous works, we propose a novel TAS scheme for multiple‐input multiple‐output wiretap channels by exploiting full channel state information. The proposed scheme achieves higher secrecy performance by selecting an antenna that maximises the secrecy rate. In our analysis, we assume that the receiver (Rx) and the eavesdropper employ either selection combining (SC) or maximal‐ratio combining (MRC) to combine the received signals, and this results in four different receiver combining arrangements. By considering Nakagami‐m fading, secrecy performance is analysed. Specifically, closed‐form expressions for the secrecy outage probability are derived, which can be used as a quality of service metric. Moreover, an asymptotic analysis is carried out and the respective diversity/array gains are obtained. The ergodic secrecy rate is also investigated for the case of multiple‐input single‐output wiretap channels. Insightful discussions are attained from our analysis. For instance, it is shown that the performance gain of MRC over SC at the Rx does not depend on the number of antennas and combining scheme at the eavesdropper. More interestingly, we observe that such a performance gain is independent of the TAS scheme used at the transmitter (Tx). On the other hand, it is shown that the secrecy gap between SC and MRC at the eavesdropper is independent of the number of antennas at the Tx, but it depends on the number of antennas at the Rx. Finally, it is demonstrated that the diversity gain is the same for all antenna configurations. Copyright © 2016 John Wiley & Sons, Ltd.
Wild Bootstrap Inference for Wildly Different Cluster Sizes
Authors: MacKinnon James G. , Webb Matthew D. 
Published: February 2016

SummaryThe cluster robust variance estimator (CRVE) relies on the number of clusters being sufficiently large. Monte Carlo evidence suggests that the ‘rule of 42’ is not true for unbalanced clusters. Rejection frequencies are higher for datasets with 50 clusters proportional to US state populations than with 50 balanced clusters. Using critical values based on the wild cluster bootstrap performs much better. However, this procedure fails when a small number of clusters is treated. We explain why CRVE t statistics and the wild bootstrap fail in this case, study the ‘effective number’ of clusters and simulate placebo laws with dummy variable regressors. Copyright © 2016 John Wiley & Sons, Ltd.
Skin and muscle permeating antibacterial nanoparticles for treating Staphylococcus aureus infected wounds
Authors: Dhanalakshmi V. , Nimal T. R. , Sabitha M. , Biswas Raja , Jayakumar R. 
Published: February 2016

AbstractMajority of the chronic wounds are infected with bacteria like Staphylococcus aureus (S. aureus). The deep tissue infections are difficult to treat using topical antibiotics, due to their poor tissue penetration. In order to treat S. aureus deep tissue infections we have developed an antibiotic delivery system using chitosan nanoparticles (CNPs). To enhance their tissue penetration these CNPs were further coated using lecithin (CLNPs). Antibiotic tigecycline was loaded into chitosan nanoparticles (tCNPs) and then coated with lecithin to generate lecithin coated tigecycline loaded chitosan nanoparticles (tCLNPs). The prepared nanoparticles were characterized using DLS, SEM, TEM and FT‐IR. The prepared CNPs, tCNPs, CLNPs and tCLNPs have the size range of 85 ± 10, 90 ± 18, 188 ± 5 and 235 ± 20 nm, respectively. The tCLNPs shows more sustained release pattern of tigecycline. The antibacterial activity of the developed nanoparticles was confirmed against laboratory and clinical strains of S. aureus using in vitro and ex vivo experiments. The ex vivo skin and muscle permeation study ensures the enhanced delivery of tigecycline to the deeper tissue. The prepared nanoparticles were hemo‐compatible and cyto‐compatible. Our study suggests that the prepared tCLNPs can be effectively used for the treatment of S. aureus infected wounds. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 104B: 797–807, 2016.
Fabrication of Hexagonal Boron Nitride Nanosheets by Using a Simple Thermal Exfoliation Process
Authors: Ko Wen‐Yin , Chen Cheng‐Yu , Chen Wei‐Hung , Lin Kuan‐Jiuh 
Published: February 2016

AbstractA simple and inexpensive method to exfoliate boron nitride powder to form boron nitride nanosheets (BNNSs) with few layers was achieved by using a physically thermal process. The obtained BNNSs were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), atomic force microscopy (AFM), X‐ray diffraction (XRD), X‐ray photoelectron spectroscopy (XPS), IR spectroscopy, and Raman spectroscopy. The size distribution of the sheets and average sheet size is in the range of 80–380 nm and 200±62 nm, respectively, and the pure phase h‐BN products were confirmed. XPS result showed the B/N atomic ratio to be 0.99. In addition, the BNNSs can well disperse in aqueous solution to form a cloudy suspension and importantly, can remain suspended for 1 month without precipitate, which would have good potential in a wide range of applications.
DFT Study of Carbon Crystals from Nested K4 Lattice to BC‐8 Structure
Authors: Hagita Katsumi , Sahara Ryoji , Kawazoe Yoshiyuki 
Published: February 2016

AbstractCarbon crystals of a nested K4 lattice and BC‐8 structure are studied. We propose a unified relationship between the nested K4 lattice and the BC‐8 structure. The atomic positons of both structures can be given by Wyckoff position 16(c) of space group No. 206 and its shifted lattice. We can obtain continuously changing configurations from the nested K4 lattice to the BC‐8 structure with one parameter. DFT calculation based on plane waves is performed in order to estimate the total energy and phonon DOS. The structure near the BC‐8 structure is found to have a stable state. We consider the nested K4 lattice a saddle point on the energy landscape and it is in a metastable state.
Synthesis of ZnO Nanoparticles Based on Zn Complex Achieved from L‐leucine
Authors: Gharagozlou Mehrnaz , Naghibi Sanaz 
Published: February 2016

AbstractIn the present study, ZnO nanoparticle preparation in a water‐base medium without using toxic chemicals was investigated. Zinc (II) acetate dehydrate, Lleucine and 5sulfosalicylaldehyde sodium salt were utilized as the starting materials. Xray diffraction analyses proved that ZnO was achieved as a unique phase. The highest value of crystallinity was obtained at 600 °C and the minimum values of crystallite size and lattice strain were reported at 400 and 500 °C, respectively. The photoluminescence spectroscopy showed that firing at 500 °C leads to decrease the point defects in ZnO structure. SEM and TEM images confirmed the relation between the firing temperature, the degree of crystallinity and the crystallite size. Firing at 400 °C leads to form ZnO nanoparticles with a size distribution ranging from 15 to 50 nm with cubic, circle and hexagonal shapes. By increasing the temperature to 500 °C, the nanoparticles dimensions increase to 30–60 nm. The particle size of sample ‘c’ is more than 50 nm. The optimum temperature to achieve the goal of this research, namely a high crystallinity and low structure defects, was found to be 500 °C.
Clinical Value of Hypochromia Markers in the Detection of Latent Iron Deficiency in Nonanemic Premenopausal Women
Authors: Urrechaga Eloísa , Borque Luís , Escanero Jesús F. 
Published: February 2016

BackgroundIron deficiency (ID) is the most common cause of anemia in fertile women and hemoglobin (Hb) within the reference interval does not exclude ID. The consequence of an imbalance between the iron requirements and supply is a reduction of red‐cell Hb content, which causes hypochromic cells. The aim of this study was to assess the reliability of new parameters low Hb density (LHD%), reticulocyte Hb equivalent (RetHe), and percentage of hypochromic erythrocytes (%HypoHe) in the detection of latent ID (LID), defined as depletion of iron stores without anemia.MethodsTwo hundred fifty consecutive nonanemic women in fertile age (18–40 years, mean 33.5 years), whose analyses had been requested by general practitioners, were included. Independent samples t‐test, receiver operating characteristic (ROC) curve analysis (gold standard for detecting LID ferritin <30 μg/l), and Cohen's kappa index were applied.ResultsOne hundred fifty‐three women had ferritin within the reference range and Hb >120 g/L; 97 (38.8%) had LID. The results were as follows: %HypoHe—AUC 0.934, cutoff 1.6%, sensitivity 85.7%, specificity 92.1%; RetHe—AUC 0.914, cutoff 29.9 pg, sensitivity 86.8%, specificity 85.7%; LHD%—AUC 0.898, cutoff 5.0%, sensitivity 85.9%, specificity 84.1%. Applying those cutoffs, agreement between ferritin and %HypoHe was κ 0.61 and 0.56 for RetHe and LHD%.ConclusionsLHD%, %HypoHe, and RetHe emerge as reliable tests for the investigation of LID and could improve the ability to detect ID before anemia is present.
Meaning Making in the Context of Disasters
Authors: Park Crystal L. 
Published: February 2016

ObjectiveUnderstanding the factors underlying adaptive psychological responses and recovery after disasters has important implications for intervention and prevention efforts. To date, little attention has been paid to successful coping processes in recovering from natural and technological disasters. This article takes a meaning making perspective to explicate how survivors successfully adapt after disasters.MethodRelevant literature is reviewed to illustrate the process of adaptation and resilience after disasters.ResultsStudies to date suggest both survivors’ global meaning, particularly their religiousness and sense of meaning, and their appraisals and meaning making after the disaster are important influences on their postdisaster resilience. Meanings made in the form of changes in global beliefs and perceived growth have been reported and shown to have inconsistent relations with adjustment.ConclusionsAlthough much more research is needed, current literature suggests that meaning making processes are central to recovery and resilience after a range of disasters.