bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progenitor Cells and Clinical Outcomes in Patients With Heart Failure
Authors: Samman Tahhan Ayman , Hammadah Muhammad , Sandesara Pratik B. , Hayek Salim S. , Kalogeropoulos Andreas P. , Alkhoder Ayman , Mohamed Kelli Heval , Topel Matthew , Ghasemzadeh Nima , Chivukula Kaavya , Ko Yi-An , Aida Hiroshi , Hesaroieh Iraj , Mahar Ernestine , Kim Jonathan H. , Wilson Peter , Shaw Leslee , Vaccarino Viola , Waller Edmund K. , Quyyumi Arshed A. 
Published: August 2017

Background
Endogenous regenerative capacity, assessed as circulating progenitor cell (PC) numbers, is an independent predictor of adverse outcomes in patients with cardiovascular disease. However, their predictive role in heart failure (HF) remains controversial. We assessed the relationship between the number of circulating PCs and the pathogenesis and severity of HF and their impact on incident HF events.

Methods and Results

We recruited 2049 adults of which 651 had HF diagnosis. PCs were enumerated by flow cytometry as CD45med
+
blood mononuclear cells expressing CD34, CD133, vascular endothelial growth factor receptor-2, and chemokine (C-X-C motif) receptor 4 epitopes. PC subsets were lower in number in HF and after adjustment for clinical characteristics in multivariable analyses, a low CD34
+
and CD34
+
/CXCR
+
cell count remained independently associated with a diagnosis of HF (
P
<0.01). PC levels were not significantly different in reduced versus preserved ejection fraction patients. In 514 subjects with HF, there were 98 (19.1%) all-cause deaths during a 2.2±1.5-year follow-up. In a Cox regression model adjusting for clinical variables, hematopoietic-enriched PCs (CD34
+
, CD34
+
/CD133
+
, and CD34
+
/CXCR4
+
) were independent predictors of all-cause death (hazard ratio 2.0, 1.6, 1.6-fold higher mortality, respectively;
P
<0.03) among HF patients. Endothelial-enriched PCs (CD34
+
/VEGF
+
) were independent predictors of mortality in patients with HF with preserved ejection fraction only (hazard ratio, 5.0;
P
=0.001).

Conclusions
PC levels are lower in patients with HF, and lower PC counts are strongly and independently predictive of mortality. Strategies to increase PCs and exogenous stem cell therapies designed to improve regenerative capacity in HF, especially, in HF with preserved ejection fraction, need to be further explored.
Tramadol sparing effect of dexmedetomidine as an adjuvant with lignocaine in preoperative stellate ganglion block for postoperative pain relief following upper limb surgeries
Authors: Thapa Deepak , Dhiman Deepanshu , Ahuja Vanita , Gombar Satinder , Gupta Ravi K 
Published: August 2017

Background: Recent literature has established the role of stellate ganglion block (SGB) for management of acute postoperative pain. The effects of dexmedetomidine as an adjuvant to lignocaine in a preoperative SGB for postoperative pain relief have not been evaluated so far. Methods: The following randomised, double-blinded, control trail included 54 patients scheduled for upper limb orthopaedic surgery under general anaesthesia. Preoperative ultrasound-guided (USG) SGB was performed in all patients. Group I (n = 18) received 3.5 mL of a solution (3 mL 2% lignocaine + 0.5 μg/kg dexmedetomidine for SGB) and 15 mL of intravenous (IV) normal saline (NS). Group II (n = 18) received 3.5 mL of a solution (3 mL 2% lignocaine + 0.5 mL NS for SGB) and 15 mL of IV NS. Group III (n = 18) received 3.5 mL of a solution (3 mL 2% lignocaine + 0.5 mL of NS for SGB) and 0.5 μg/kg dexmedetomidine in 15 mL of IV NS. Postoperatively tramadol consumption and Visual Analogue Scale (VAS) score were recorded up to 48 hours. Results: The cumulative tramadol consumption at the end of 48 hours (p = 0.01) was significantly reduced in the group I as compared to group II. In group I, postoperative VAS at rest was significantly reduced up to 12 hours postoperatively as compared to group II (p = 0.05). The cumulative tramadol consumption was not reduced significantly in group III compared to group II (p = 0.51). Conclusion: Dexmedetomidine as an adjuvant to SGB along with lignocaine produced a significant tramadol sparing effect and superior analgesia as compared to IV dexmedetomidine and control group.1
Impact of cytogenetic abnormalities in adults with Ph-negative B-cell precursor acute lymphoblastic leukemia
Authors: Lafage-Pochitaloff Marina , Baranger Laurence , Hunault Mathilde , Cuccuini Wendy , Lefebvre Christine , Bidet Audrey , Tigaud Isabelle , Eclache Virginie , Delabesse Eric , Bilhou-Nabéra Chrystèle , Terré Christine , Chapiro Elise , Gachard Nathalie , Mozziconacci Marie-Joelle , Ameye Geneviève , Porter Sarah , Grardel Nathalie , Béné Marie C. , Chalandon Yves , Graux Carlos , Huguet Françoise , Lhéritier Véronique , Ifrah Norbert , Dombret Hervé 
Published: August 2017

Abstract
Multiple cytogenetic subgroups have been described in adult Philadelphia chromosome (Ph)-negative B-cell precursor (BCP) acute lymphoblastic leukemia (ALL), often comprising small numbers of patients. In this study, we aimed to reassess the prognostic value of cytogenetic abnormalities in a large series of 617 adult patients with Ph-negative BCP-ALL (median age, 38 years), treated in the intensified Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)-2003/2005 trials. Combined data from karyotype, DNA index, fluorescence in situ hybridization, and polymerase chain reaction screening for relevant abnormalities were centrally reviewed and were informative in 542 cases (88%), allowing classification in 10 exclusive primary cytogenetic subgroups and in secondary subgroups, including complex and monosomal karyotypes. Prognostic analyses focused on cumulative incidence of failure (including primary refractoriness and relapse), event-free survival, and overall survival. Only 2 subgroups, namely t(4;11)/KMT2A-AFF1 and 14q32/IGH translocations, displayed a significantly worse outcome in this context, still observed after adjustment for age and after censoring patients who received allogeneic stem cell transplantation (SCT) in first remission at SCT time. A worse outcome was also observed in patients with low hypodiploidy/near triploidy, but this was likely related to their higher age and worse tolerance to therapy. The other cytogenetic abnormalities, including complex and monosomal karyotypes, had no prognostic value in these intensive protocols designed for adult patients up to the age of 60 years.
The effect of music in gynaecological office procedures on pain, anxiety and satisfaction: a randomized controlled trial
Authors: Mak N. , Reinders I. M. A. , Slockers S. A. , Westen E. H. M. N. , Maas J. W. M. , Bongers M. Y. 
Published: August 2017

Abstract
Background
Pain can interfere with office procedures in gynaecology. The aim of this study is to measure the positive effect of music in gynaecological office procedures.

Methods
A randomized controlled trial was performed between October 2014 and January 2016. Women scheduled for an office hysteroscopy or colposcopy were eligible for randomization in the music group or control group. Stratification for hysteroscopy and colposcopy took place. The primary outcome is patients’ level of pain during the procedure measured by the visual analogue scale (VAS). Secondary outcomes include patients’ level of pain after the procedure, anxiety and satisfaction of patient and doctor.

Results
No positive effect of music on patients’ perception of pain during the procedure was measured, neither for the hysteroscopy group (57 mm vs. 52 mm) nor for the colposcopy group (32 mm vs. 32 mm). Secondary outcomes were also similar for both groups.

Conclusions
This study showed no positive effect of music on patients’ level of pain, anxiety or satisfaction of patient or doctor for office hysteroscopy and colposcopy. We believe a multimodal approach has to be used to decrease patient distress in terms of pain and anxiety, with or without music.

Trial registration
Dutch Trial Register, NTR4924
Existence and uniqueness of solution for a class of nonlinear degenerate elliptic equation in weighted Sobolev spaces
Authors: Cavalheiro Albo Carlos 
Published: August 2017

Abstract
In this work we are interested in the existence and uniqueness of solutions for the Navier problem associated to the degenerate nonlinear elliptic equations

Δ
(v
(
x
)

|

Δ
u

|

r
−
2

Δ
u
)
−

∑

j
=
1

n

D
j

[

w
1

(
x
)

𝒜
j

(
x
,
u
,
∇
u
)
]

+

b
(
x
,
u
,
∇
u
)

w
2

(
x
)
=

f
0

(
x
)
−

∑

j
=
1

n

D
j

f
j

(
x
)
,

in

Ω

$$\matrix{{\Delta {\rm{(v}}({\rm{x}})\left| {\Delta {\rm{u}}} \right|^{{\rm{r}} - 2} \Delta {\rm{u}}) - \sum\limits_{{\rm{j}} = 1}^{\rm{n}} {{\rm{D}}_{\rm{j}} [{\rm{w}}_1 ({\rm{x}}){\cal{A}}_{\rm{j}} ({\rm{x}},{\rm{u}},\nabla {\rm{u}})]} } \hfill \cr { + \;{\rm{b}}({\rm{x}},{\rm{u}},\nabla {\rm{u}})\;{\rm{w}}_2 ({\rm{x}}) = {\rm{f}}_0 ({\rm{x}}) - \sum\limits_{{\rm{j}} = 1}^{\rm{n}} {{\rm{D}}_{\rm{j}} {\rm{f}}_{\rm{j}} ({\rm{x}}),\;\;\;\;\;{\rm{in}}\;\Omega } }}$$

in the setting of the Weighted Sobolev Spaces.
Semi-permanent hair dyes degradation at W/WO3 photoanode under controlled current density assisted by visible light
Authors: Fraga Luciano Evangelista , Guaraldo Thais Tasso , de Araújo Souza Bárbara Camila , Zanoni Maria Valnice Boldrin 
Published: August 2017

AbstractThe indiscriminate use of hair dyes has attracted great deal of attention due to its toxicological and mutagenic aspects demonstrated by some of these substances. Thus, the effluent from beauty salons and domestic sewages if not properly treated can reach water treatment plants and water sources, enhancing human health and environmental protection concern. This work explores the application of photoelectrocatalytic process on Basic Brown 16 and Basic Blue 99 degradation as model of basic hair dyes pollutants. W/WO
Design of One-Bit Magnitude Comparator using Photonic Crystals
Authors: Rathi Sapna , Swarnakar Sandip , Kumar Santosh 
Published: August 2017

Abstract
At present, photonic crystals (PhCs) are used to design various combinational and sequential circuits. In this paper, an all-optical one-bit magnitude comparator is proposed using PhC waveguide without using nonlinear material. It is based on beam interference principle, using T-shaped lattice with silicon dielectric rods in air background. It is demonstrated through finite-difference time-domain simulation and verified numerically using MATLAB simulation. The size of PhC lattice structure can be as small as 19.167a×19.167a, where ‘a’ is the lattice constant of the PhC.
A New Perspective on Regional Tax Burden Differences in China
Authors: Xi Wei , Xu Jun 
Published: August 2017

AbstractRegional tax burden difference is related to regional sustainable development and social interests balance. Based on the calculation of the tax burden of 31 provinces and cities in 1995–2013, this paper puts forward that the over-statement of GDP is an important reason that causes the deviation of tax share and economic share. By using spatial econometric method, the results show that the economy as a whole is overvalued; investment in fixed assets, the proportion of secondary industry and state-owned economy have positive effects on regional GDP overestimated; per capita income and R&D have significantly negative effects on regional tax growth. Besides, the regional tax burden has spatial autocorrelation characteristic. This paper explains the abnormal difference of regional tax burden from a new perspective.
Impact of Nocturnal Natural Ventilation On the Energy Consumption of Buildings
Authors: Uciu Felicia , Catalina Tiberiu , Vartires Andreea , Colda Iolanda 
Published: August 2017

Abstract
The analysis presented in this paper is dealing with the correct and energy efficient measures of cooling buildings through nocturnal natural ventilation. Using this solution is proved in this article to be efficient and can reduce substantially the cooling demand. In order to establish the factors influencing the process of passively cooling a building (the ventilation volume, exterior temperature, thermal capacity of the building, possible duration of the ventilation), we have chosen different buildings, which we have placed them in different temperature zones of Romania. The study is based on multiple simulations realized with a time step of one hour, with the following variations: the climatic parameters, the thermal characteristics of the building, the air flow during night time, the proposed interior temperature. Since the study consisted of numerous simulations, in order to treat the results we have used statistical methods that cover the practical and possible situations, and proved the efficiency of nocturnal ventilation.
Stability Analysis of a Coal Combustion Residuals Impoundment
Authors: Verdeș Mihai 
Published: August 2017

Abstract
The overall stability of the Rovinari dry ash slurry impoundment is analyzed using a coupled seepage-stability analysis with the Finite Element Method in a bidimensional model. To better understand the behavior of such a complex structure, based on the material properties presented in Table 2, the hypotheses presented in Table 4 and described as such, a number of 9 general hypotheses were analyzed, at 178.00 m a.s.l. deposit elevation and final designed height of approximately 35.30 m which corresponds to 191.3 m a.s.l.. The results are presented in tabular form, only 8 diagrams are selected which show the Factor of Safety for hypothesis 0 and 3 which are considered to best describe the real-life conditions regarding the boundary conditions used. The results show that even at maximum designed height, the deposit is stable in the most realistic worst-case hypothesis 3, with a Factor of Safety of 1.177.
Effect of Nitrogen Fertiliser on Growth and Production of Apples in the Conditions of Latvia
Authors: Pole Valentīna , Missa Imants , Rubauskis Edgars , Kalva Egils , Kalva Sanita 
Published: August 2017

Abstract
Nitrogen is a nutrient necessary for many functions of plants, e.g. shoot growth, fruit and flower bud set, and fruit size. In Latvia use of mineral fertilisers is limited by EU Directives and Regulations developed on the basis of the Guidelines of Integrated Production. The aim of the study was to investigate the effect of nitrogen (N) fertiliser on apple growth and production in the conditions of Latvia. The study was performed during 2013 to 2015. In an apple trial, seven cultivars on rootstock B.396 were planted in 2009. There were two fertiliser treatments: without fertilising and N 6 g·m-2. Significant effect of treatment was observed only in cultivar ‘Ligol’. Tree crown in the N treatment was over-dense, shoots too long, yet all cultivars had over-long shoots also in the unfertilised treatment. Effect of nitrogen in regard to amounts of acceptable and unacceptable shoots of the cultivars included in trial was negative. Nitrogen significantly increased the amount of unacceptable shoot types of cultivars ‘Gita’, ‘Rubin’ (Kazakhstan), and ‘Ligol’. Additional nitrogen as fertiliser had no significant effect on growth and yield of cultivars ‘Antei’, ‘White Transparent’ and ‘Konfetnoye.’ The cumulative yield of ‘Kovalenkovskoye’ and ‘Ligol’ was positively affected by nitrogen fertiliser. The most pronounced biennial yielding was observed for cultivar ‘Rubin’. Cultivar ‘Ligol’ had the most active and longer vegetation, especially in the nitrogen fertilisers treatment.
Use of Genetic Diversity of the Genus Prunus L. in Selection of Clonal Rootstocks for Stone Fruit Crops and Features of Their Reproduction
Authors: Eremin Gennadiy V. , Podorozhniy Vladimir N. , Eremina Oksana V. 
Published: August 2017

Abstract
On the basis of diversity of wild types of the genus Prunus L. (P. cerasifera, P. armeniaca, P. persica, P. fruticosa, P. lannesiana, P. maackii, P. tomentosa, P. pumila, and P. incana) in the collection of the Krymsk Experiment Breeding Station, highly adaptive, medium or weak vigour clonal rootstocks for stone fruit crops with good compatibility with grafted cultivars were selected: for plum, apricot and peach - Kuban 86, VVA-1, Evrika 99, Zarevo (Glow), Alab 1, Speaker, Best, VSV-1; and for sweet cherries and sour cherries - L-2, LC-52, VSL-1, VSL-2, and RVL-9. Part of the rootstocks were tested and successfully used in different parts of Russia and some near and far countries. The applied integration of tissue culture in vitro in the selection process at the station considerably promoted the rapid introduction of new rootstocks into world production. Technologies were developed for microclonal reproduction, and green and woody cuttings. The revealed light rooting of woody cuttings of stocks Kuban 86, Evrika 99, Zarevo, Best, VSL-1, RVL-9 (50-80%) allowed to develop technology for growing of young plants on these rootstocks directly in the first field of the nursery.
Fruit Set of Several Sour Cherry Cultivars in Latvia Influenced by Weather Conditions Before and During Flowering
Authors: Feldmane Daina , Ruisa Silvija , Pole Valentīna , Butac Madalina , Militaru Madalina 
Published: August 2017

Abstract
Fruit set is a crucial stage in the process of yield formation, which is influenced by environmental factors, growing technologies and peculiarities of genotype. The aim of the study was to evaluate the quality of pollen (viability and germination capacity) and the effect of weather before and during flowering on fruit set in sour cherry cultivars ‘Latvijas Zemais’, ‘Zentenes’, ‘Bulatnikovskaya’, and ‘Orlica’. The research was carried out in Institute of Horticulture (Latvia University of Agriculture) in 2009-2016. Good pollen viability and germination was found for cultivars ‘Latvijas Zemais’ and ‘Bulatnikovskaya’. Negative effects of increasing air temperature (in the range of 7.7 to 17.5 °C) and relative humidity (in the range of 51.4 to 88.5%) was observed for all cultivars during flowering. The effects of diurnal temperature fluctuations, wind and the amount of days with precipitation differed depending on sour cherry cultivar.
An Optimised Protocol for Fluorescent-dUTP Based SSR Genotyping and its Application to Genetic Mapping in Eucalyptus
Authors: Li F. , Gan S. 
Published: August 2017

Abstract
Integration of fluorescent-dUTP in polymerase chain reaction (PCR) appears to be a sound method for fluorescence labelling of amplicons in genotyping with simple sequence repeats (SSRs) using an automated sequence analyser. However, the method has not been explored in terms of performance optimisation and cost control. In this paper, we optimised the protocol for fluorescent-dUTP based SSR genotyping in a case study with Eucalyptus. A combination of low dNTP concentration (25 μM each) in PCR reaction and a touchdown PCR programme contributed to increase dramatically the fluorescent intensity of SSR amplicons, thereby facilitating accurate and multiplexed scoring of SSR alleles. The usefulness of the optimised protocol was demonstrated in its application to genetic mapping of SSR loci onto E. urophylla and E. tereticornis linkage maps constructed previously. The protocol optimised here would provide a reliable and economical assay for sequencer-based SSR genotyping in a wide range of biological applications.
Clonal Variation in Lateral and Basal Rooting of Populus Irrigated with Landfill Leachate
Authors: Zalesny R. S. , Zalesny J. A. 
Published: August 2017

Abstract
Successful establishment and productivity of Populus depends upon adventitious rooting from: 1) lateral roots that develop from either preformed or induced primordia and 2) basal roots that differentiate from callus at the base of the cutting in response to wounding. Information is needed for phytotechnologies about the degree to which Populus adventitious rooting is controlled by effects of individual genotypes, waste waters used as alternative fertigation sources, and their interactions. Our objective was to irrigate twelve Populus clones with well water (control) or municipal solid waste landfill leachate and to test for differences between initiation of lateral versus basal roots, as well as root growth rate and distributional trends for both root types. We evaluated number and length of lateral roots initiated from upper, middle, and lower thirds of the cutting, as well as basal callus roots. Overall, leachate irrigation affected lateral roots but not basal roots, and there was broad clonal variation between and within root types. On average, there were 129% more lateral than basal roots, which ranged from 3 to 27 (lateral) and 2 to 10 roots (basal). The percent advantage of number of roots from the middle portion of the cutting relative to other sections was 120% (upper), 193% (lower), and 24% (basal). Clones, treatments, and their interaction did not affect root growth rate, which ranged from 1.5 ± 0.6 to 3.4 ± 0.3 cm d−1, with a mean of 2.3 ± 0.2 cm d−1. These results contribute baseline information for clonal selection needed to establish Populus for phytotechnologies, energy, and fiber.
Genetic Variation in Needle Epicuticular Wax Characteristics in Pinus Pinceana Seedlings
Authors: Ramirez-Herrera C. , Percy K. E. , Loo J. A. , Yeates L. D. , Vargas-Hernandez J. 
Published: August 2017

Abstract
Seedlings from each of 12 Pinus pinceana populations from throughout the species’ range in Mexico were evaluated in a common-garden test to (1) determine the level of genetic variation and genetic structure of epicuticular needle wax quantity, (2) examine differences in wax chemical composition, and (3) seek evidence for an adaptive response in wax composition and quantity across environmental and geographic gradients. Regions and populations within regions showed high variation (38.2% and 10.5%, respectively, of the total variation) in wax quantity. Epicuticular wax recovered from primary needles of P. pinceana comprised eight classes. Secondary alcohols (71.7%) were the major homologs identified by gas chromatography. Seedlings from the northern region were separated based on wax composition from seedlings from the central and southern regions by canonical discriminant analysis. A strong differentiation among regions (QSTR
=0.571) and populations within regions (QSTP(R)
=0.384) was observed for wax quantity. Data on wax quantity and chemical composition indicate that physicochemical characteristics of epicuticular wax may show adaptation of P. pinceana to local environments.
Helminths of Wild Predatory Mammals of Ukraine. Nematodes
Authors: Varodi E. I. , Malega A. M. , Kuzmin Y. I. , Kornyushin V. V. 
Published: August 2017

Abstract
The article summarizes information on the nematodes parasitic in wild Carnivora of Ukraine. Totally, 50 species of nematodes are known to parasitise carnivorans in the country, 30 species were registered in the present study. Nematodes were found in 14 species of examined hosts from the families Canidae, Mustelidae and Felidae. Maximum diversity of nematodes of carnivorans was observed in Polissia (forest zone in the north of the country) and in Kherson Region in the south. Hosts from the family Canidae harboured 19 nematode species; studied species of the Mustelidae were infected with 15 nematode species, 6 of them were also found in Canidae. The wildcat (Felis silvestris Schreber) and the lynx (Lynx lynx Linnaeus) harboured only two species of nematodes, both are specific parasites of these hosts. The most comprehensive information concerns the nematode communities of the red fox (Vulpes vulpes Linnaeus) and the wolf (Canis lupus Linnaeus), with 19 and 9 nematode species found, correspondingly. From 1 to 6 nematode species were found in other species of carnivorans.