bluuebunny/crossref_metadata_2025_split huggingface dataset:
A aplicação das TIC’S no sistema prisional
Authors: Santos Silvana Maria Aparecida Viana 
Published: September 2024

Este estudo investigou a efetividade das Tecnologias da Informação e Comunicação (TIC’s) no sistema prisional, focando em como essas tecnologias poderiam ser utilizadas para melhorar o acesso à educação e contribuir para a ressocialização dos detentos. O objetivo geral foi analisar o impacto das TIC’s na educação prisional e sua capacidade de preparar os detentos para a reintegração social. A metodologia utilizada foi a revisão bibliográfica, que consistiu na análise de estudos e artigos relevantes sobre o tema, coletados em bases de dados acadêmicas. Os resultados indicaram que, embora as TIC’s tenham o potencial de ampliar o acesso à educação no ambiente prisional, sua efetividade é limitada por desafios como infraestrutura inadequada, falta de formação para educadores e barreiras culturais. A análise dos dados sugeriu que, quando bem implementadas, as TIC’s podem contribuir para a educação e ressocialização dos detentos, mas ressaltou a necessidade de investimentos em infraestrutura e capacitação. As considerações finais destacaram a importância de estudos futuros para explorar novas metodologias pedagógicas e acompanhar a aplicação das TIC’s a longo prazo, visando maximizar seus benefícios no contexto prisional.
Nurse-midwifery students’ experiences in high-fidelity simulation: a focus group study
Authors: Carvalho Júlia , Brás Cláudia , Duarte Helena , Fonseca José , João Tomás Maria , Polónio Maria Inês , Caetano Ana-Bela 
Published: September 2024

Introduction: Active teaching methodologies, particularly those using high-fidelity simulation, stand out in nursing education for their ability to facilitate the development of students' technical-scientific and non-technical skills, as well as prepare them for clinical practice. High-fidelity simulation using realistic models is an effective tool for improving students' communication skills, leadership and critical thinking. This study aims to explore nurse-midwifery students’ learning experiences in high-fidelity simulation.Methods: Explorative qualitative study using two focus groups interviews with nurse-midwifery students at the Higher School of Nursing. Qualitative data were analyzed using content analysis. Results: Two main themes emerged from content analysis: (i) Simulation-based learning and (ii) Simulation-based teaching. The first theme includes three categories: development of technical-scientific skills, development of non-technical skills, and preparation for internship. The second theme also includes three categories: enhancing theoretical knowledge, facilitating teaching, and post-scenario discussion (debriefing). Conclusions: The use of high-fidelity simulation as a teaching strategy in the training of nurse-midwifery students contributed to the development of technical and non-technical skills essential to nursing practice
CÁC YẾU TỐ NGUY CƠ BỆNH PHỔI TẮC NGHẼN MẠN TÍNH TẠI BỆNH VIỆN ĐA KHOA TRUNG TÂM AN GIANG
Authors: Trương Văn Lâm , Tô Hồng Ánh 
Published: September 2024

Đặt vấn đề: Bệnh phổi tắc nghẽn mạn tính (COPD) là bệnh mãn tính phổ biến nhất trên toàn thế giới, không chỉ dẫn đến suy giảm chức năng phổi và chất lượng cuộc sống liên tục mà còn trở thành gánh nặng kinh tế lớn cho cá nhân, gia đình và xã hội. Mục tiêu nghiên cứu: Xác định các yếu tố nguy cơ bệnh phổi tắc nghẽn mạn tính tại Bệnh viện Đa khoa Trung tâm An Giang.Đối tượng và phương pháp nghiên cứu: Bệnh nhân đến khám tại phòng khám hô hấp - Bệnh viện Đa khoa Trung tâm An Giang trong thời gian từ 01/2023 đến 10/2023. Kết quả: Trong nghiên cứu chúng tôi, có 53 bệnh nhân, tuổi trung bình 62± 1,3, tuổi thấp nhất 40, tuổi cao nhất 86, nam chiếm 79,2%, nữ chiếm 20,8%; các yếu tố ngu cơ như tiền sử hút thuốc lá (OR = 5,2; KTC 95%: 1,311,32; P =0,02), tiếp xúc với khói bụi (OR = 2,3; KTC 95%: 1,2-8,6; P =0,04), và tiền sử lao phổi cũ (OR = 3,4; KTC 95%: 1,2-9,7; P =0,02) là các yếu tố nguy cơ mắc bệnh COPD. Kết luận: Các yếu tố như tiền sử hút thuốc lá, có tiếp xúc khói bụi thường xuyên, tiền sử lao phổi cũ là những yếu nguy cơ độc lập COPD, có ý nghĩa thống kê, p< 0,05.
NGHIÊN CỨU VỀ THỰC VẬT HỌC, MÃ VẠCH ADN VÀ PHÂN TÍCH SƠ BỘ THÀNH PHẦN HÓA HỌC CỦA CÂY DIẾP CÁ (Houttuynia cordata Thunb. Saururaceae)
Authors: Nguyễn Thị Trang Đài , Lê Thị Thanh Yến , Nguyễn Ngọc Nhã Thảo 
Published: September 2024

Đặt vấn đề: Cây Diếp cá (rau dấp cá) từ rất lâu đã trở thành một vị thuốc quen thuộc, có tác dụng chữa trĩ, đinh nhọt, sởi, đau mắt đỏ do vi khuẩn mủ xanh, bí tiểu tiện, phụ nữ kinh nguyệt không đều, có thể phối hợp với một số vị thuốc Nam khác chữa sốt xuất huyết. Mục tiêu nghiên cứu: Nghiên cứu về thực vật học, mã vạch ADN, và thành phần hóa học của dược liệu Diếp cá. Đối tượng và phương pháp nghiên cứu: Dược liệu Diếp cá được thu hái tại thành phố Cần Thơ, dược liệu được khảo sát thực vật học bằng phương pháp vi học, kiểm tra mã vạch ADN bằng phương pháp điện di trên gel Agarose, khảo sát thành phần hóa học bằng phương pháp chiết xuất dược liệu với ba dung môi có độ phân cực tăng dần, định tính các hợp chất trong dịch chiết bằng các thuốc thử đặc trưng, định tính các hợp chất chính trong dược liệu bằng sắc ký lớp mỏng. Kết quả: Cung cấp bộ hình ảnh về đặc điểm hình thái, cấu tạo vi phẫu và soi bột dược liệu, mã vạch AND và xác định được thành phần hóa học của dược liệu chứa flavonoid, tinh dầu, alkaloid, tannin. Kết luận: Từ kết quả nghiên cứu đã cung cấp dữ liệu về đặc điểm thực vật học và thành phần hóa học cho dược liệu Diếp cá, góp phần quan trọng cho việc lựa chọn sử dụng dược liệu này một cách hợp lý, an toàn và phát triển nghiên cứu thành phần hóa học của Diếp cá theo định hướng tác dụng sinh học.
Análisis de Factores de Riesgo para el Desarrollo de Infecciones Asociadas a la Atención Sanitaria (IAAS) en Cuidados de Enfermería de Catéteres Centrales y Periféricos
Authors: Aymar Contreras Yesenia Elizabeth , Torres Díaz Dimas Alexander , Balseca Diaz Adela Nathaly , Granda Cardenas Ema Cecibel 
Published: September 2024

Las infecciones relacionadas con el uso de catéteres venosos centrales y periféricos representan un desafío significativo en el ámbito de la atención sanitaria, especialmente en los cuidados de enfermería. La higiene de manos y las técnicas asépticas inadecuadas son factores reconocidos que contribuyen a estas infecciones. Esta revisión tiene como objetivo evaluar los factores de riesgo asociados a las infecciones de catéteres, identificar las deficiencias en las prácticas actuales y proponer estrategias para mejorar la atención al paciente. Se llevó a cabo una revisión exhaustiva de la literatura, analizando 12 investigaciones relevantes publicados en los últimos seis años.
Los estudios seleccionados fueron evaluados por su rigor metodológico y pertinencia temática, abarcando enfoques variados desde estudios empíricos hasta revisiones sistemáticas. Los hallazgos revelan que los factores críticos incluyen la mala higiene de manos, la técnica aséptica deficiente, la prolongación del tiempo de permanencia del catéter y la falta de educación continua. Se concluye que es esencial implementar programas de capacitación estandarizados y protocolos de higiene rigurosos para reducir la incidencia de infecciones.
Además, el monitoreo regular del sitio de inserción y la rotación oportuna de los catéteres deben ser prácticas clínicas rutinarias. Se sugiere realizar investigaciones futuras para evaluar intervenciones específicas y tecnologías emergentes que optimicen la gestión de catéteres, adaptando estrategias a diferentes contextos hospitalarios para mejorar la efectividad en la prevención de infecciones.
Do Racial Disparities Impact Healthcare Costs and Resource Utilization after Total Joint Replacements?
Authors: Redden Anna , Rohatgi Atharva , Kane Katelyn , Baran Jessica V , Donley Connor , Jackson Garrett R , Sabesan Vani J 
Published: September 2024

Background Racial disparities currently exist in healthcare and can have a significant impact on patient outcomes and access to quality care. Previous studies have indicated that black patients are more likely to experience delays in treatment and increased surgical complications. Hispanic patients have more comorbidities and increased complications when undergoing orthopaedic surgeries. The purpose of this study was to evaluate the impact of racial disparities on postoperative complications and readmission rates following Total Joint Arthroplasty (TJA). Methods The largest single healthcare network database was queried to identify total joint arthroplasty patients treated in a single division between 2017 and 2021. Patient demographics including age, race, gender, and comorbidities were collected. Logistic regression and odds ratio point estimate analyses were utilized to assess for associations between race (defined as Whites, Blacks, Hispanics, Asians, and Others) and postoperative medical complications and surgical complications, which were collected for all patients. Patient outcomes included length of stay, hospital readmission status at 30 and 90 days postoperative, and emergency room (ER) visits up to 90 days. Results A total of 16,940 patients were included in this analysis consisting of 62% female, a mean age of 71 years and mean BMI of 29.4 kg/m2 . Racial demographics consisted of 61.6% White, 12.3% Black, 24.1% Hispanic, 0.8% Asian, and 1.2% Other. Race was not significantly associated with increased readmissions at 30 days (p=0.2215) and hispanic patients were 14% less likely to be readmitted within 90 days (p = 0.0208) but were not found to have differences in ER visits when compared to White patients. Black and Asian patients were not significantly more likely to visit the ER within 90 days or to be readmitted to the hospital within 90 days when compared to White patients. Race was not significantly associated with postoperative medical complications or surgical complications. Conclusions This study found a higher readmission rate of up to 20% for total joint arthroplasty patients within 90 days of follow-up. Although race did not appear to be a significant determinant of additional ER visits or readmissions, there was some variation seen amongst Hispanic patients undergoing TJR with a lower likelihood of readmission at 60 and 90 days postoperative.
Saving Our Pollinators: How to Combat Climate Change’s Effects on Bees
Authors: Soytemiz Ihsan 
Published: September 2024

Saving Our Pollinators” examines the multifaceted impacts of climate change on bees and offers strategies to ensure the survival of these vital pollinators. The chapter highlights how rising temperatures, changing rainfall patterns and increased frequency of extreme weather events are disrupting bees’ habitats, food sources and reproductive cycles. These environmental changes can lead to incompatibilities with the plants that bees pollinate, difficulties for bees to find food and problems with plant reproduction.
Here are the main ways in which climate change is affecting bees:
* **Changing Flowering Times and Phenological Incompatibility:** Climate change alters the flowering times of plants, making it harder for bees to find food and causing negative impacts on their populations.
* Rising temperatures, extreme weather events, urbanization and agricultural expansion destroy or alter bees’ habitats, making it harder for them to survive and reproduce.
** **Increased Pests and Diseases:** A warming climate facilitates the spread and proliferation of pests and pathogens that harm bees. Pests such as the Varroa destructor mite and the small hive beetle are causing increasing problems due to their expanded range due to climate change.**Feeding Stress:** Climate change significantly affects the nutritional health of bees by altering the composition of plant species in a region. Access to diverse food sources is crucial for bees to survive.
To combat these challenges, the chapter proposes several strategies:
* **Promote Biodiversity:** Increasing the diversity of native flowering plants provides bees with a continuous and nutritious food source throughout the year.
* Protecting existing natural habitats, restoring degraded areas, and integrating bee-friendly practices in both urban and agricultural settings create safe and resource-rich environments for bees to thrive.
* Reducing Pesticide Use:** Adopting Integrated Pest Management (IPM) practices and transitioning to organic farming methods minimizes chemical exposure to bees.
* Agroecological practices, crop rotation, polycultures and permaculture systems help create healthier and more diverse ecosystems for bees to thrive.
* Investing in robust research and monitoring programs is crucial to understanding changes affecting bee populations and adapting conservation strategies accordingly.Implementing these strategies can mitigate the negative impacts of climate change on bees and contribute to a more resilient and sustainable environment.
SpLitteR: diploid genome assembly using TELL-Seq linked-reads and assembly graphs
Authors: Tolstoganov Ivan , Chen Zhoutao , Pevzner Pavel , Korobeynikov Anton 
Published: September 2024

Background
Recent advances in long-read sequencing technologies enabled accurate and contiguous de novo assemblies of large genomes and metagenomes. However, even long and accurate high-fidelity (HiFi) reads do not resolve repeats that are longer than the read lengths. This limitation negatively affects the contiguity of diploid genome assemblies since two haplomes share many long identical regions. To generate the telomere-to-telomere assemblies of diploid genomes, biologists now construct their HiFi-based phased assemblies and use additional experimental technologies to transform them into more contiguous diploid assemblies. The barcoded linked-reads, generated using an inexpensive TELL-Seq technology, provide an attractive way to bridge unresolved repeats in phased assemblies of diploid genomes.

Results
We developed the SpLitteR tool for diploid genome assembly using linked-reads and assembly graphs and benchmarked it against state-of-the-art linked-read scaffolders ARKS and SLR-superscaffolder using human HG002 genome and sheep gut microbiome datasets. The benchmark showed that SpLitteR scaffolding results in 1.5-fold increase in NGA50 compared to the baseline LJA assembly and other scaffolders while introducing no additional misassemblies on the human dataset.

Conclusion
We developed the SpLitteR tool for assembly graph phasing and scaffolding using barcoded linked-reads. We benchmarked SpLitteR on assembly graphs produced by various long-read assemblers and have demonstrated that TELL-Seq reads facilitate phasing and scaffolding in these graphs. This benchmarking demonstrates that SpLitteR improves upon the state-of-the-art linked-read scaffolders in the accuracy and contiguity metrics. SpLitteR is implemented in C++ as a part of the freely available SPAdes package and is available at https://github.com/ablab/spades/releases/tag/splitter-preprint.
Analysis of undergraduate cell biology contents in Brazilian public universities
Authors: Mermelstein Claudia , Costa Manoel Luis 
Published: January 2017

AbstractThe enormous amount of information available in cell biology has created a challenge in selecting the core concepts we should be teaching our undergraduates. One way to define a set of essential core ideas in cell biology is to analyze what a specific cell biology community is teaching their students. Our main objective was to analyze the cell biology content currently being taught in Brazilian universities. We collected the syllabi of cell biology courses from public universities in Brazil and analyzed the frequency of cell biology topics in each course. We also compared the Brazilian data with the contents of a major cell biology textbook. Our analysis showed that while some cell biology topics such as plasma membrane and cytoskeleton was present in ∼100% of the Brazilian curricula analyzed others such as cell signaling and cell differentiation were present in only ∼35%. The average cell biology content taught in the Brazilian universities is quite different from what is presented in the textbook. We discuss several possible explanations for these observations. We also suggest a list with essential cell biology topics for any biological or biomedical undergraduate course. The comparative discussion of cell biology topics presented here could be valuable in other educational contexts.
13cRA regulates the differentiation of antler chondrocytes through targeting Runx3
Authors: Zhang Hong‐Liang , Cao Hang , Yang Zhan‐Qing , Geng Shuang , Wang Kai , Yu Hai‐Fan , Guo Bin , Yue Zhan‐Peng 
Published: January 2017

AbstractAlthough 13cRA is involved in the regulation of cellular proliferation and differentiation, its physiological roles in chondrocyte proliferation and differentiation still remain unknown. Here, we showed that 13cRA could induce the proliferation of sika deer antler chondrocytes and expression of Ccnd3 and Cdk6. Administration of 13cRA to antler chondrocytes resulted in an obvious increase in the expression of chondrocyte marker Col II and hypertrophic chondrocyte marker Col X. Silencing of Crabp2 expression by specific siRNA could prevent the 13cRA‐induced up‐regulation of Col X, whereas overexpression of Crabp2 showed the opposite effects. Further study found that Crabp2 mediated the regulation of 13cRA on the expression of Runx3 which was highly expressed in the antler cartilage and inhibited the differentiation of antler chondrocytes. Moreover, attenuation of Runx3 expression greatly raised 13cRA‐induced chondrocyte differentiation. Simultaneously, 13cRA could stimulate the expression of Cyp26a1 and Cyp26b1 in the antler chondrocytes. Inhibition of Cyp26a1 and/or Cyp26b1 reinforced the effects of 13cRA on the expression of Col X and Runx3, while overexpression of Cyp26b1 rendered the antler chondrocytes hyposensitive to 13cRA. Collectively, 13cRA may play an important role in the differentiation of antler chondrocytes through targeting Runx3. Crabp2 enhances the effects of 13cRA on chondrocyte differentiation, while Cyp26a1 and Cyp26b1 weaken the sensitivity of antler chondrocytes to 13cRA.
Evaluation of catalyst leaching in silica supported zirconocene alumino hydride catalysts
Authors: Comparán‐Padilla Víctor E. , Pérez‐Berúmen Catalina M. , Cadenas‐Pliego Gregorio , Rodríguez‐Hernández María T. , Collins Scott , Pérez‐Camacho Odilia 
Published: January 2017

AbstractZirconocene aluminohydride complexes (e.g. nBuCp2ZrH3AlH2) afford higher MW polyethylene at significantly higher activity than their zirconocene dichloride counterparts (nBuCp2ZrCl2) when activated by methylaluminoxane (MAO). In this work, supported catalysts with different Al:Zr ratios on SiO2, modified with MAO were prepared, and evaluated for their tendency towards leaching in ethylene polymerization, using additional MAO or other alkylaluminum compounds. The extent of catalyst leaching was estimated by comparing kinetic data of filtered versus unfiltered catalysts during ethylene polymerization. Polydispersities and molecular weights of the HDPE obtained using filtered versus unfiltered catalysts were also compared under similar polymerization conditions. Polyethylene morphologies obtained in homogeneous and heterogeneous phase were compared by SEM. Bulk densities of the HDPE were evaluated and related to the leaching in the polymerizations.
Effects of Water Intercalation and Tribochemistry on MoS2 Lubricity: An Ab Initio Molecular Dynamics Investigation
Authors: Levita Giacomo , Righi Maria C. 
Published: January 2017

AbstractTo date, no clear conclusion has been reached on the atomistic mechanisms that govern the observed decrease of lubricating capabilities of MoS2 in humid environments. Based on ab initio molecular dynamic calculations, we show that intercalated water molecules hinder the sliding motion of both regular and defective layers considerably, with the velocities decaying exponentially with time. However, in the presence of an applied load and exposed edge terminations, water is rapidly removed from the interface and is adsorbed on the edges either in undissociated form or as OH/H fragments. These outcomes suggest that the interlayer slipperiness can be reduced by the presence of water even in the absence of any chemical oxidation. Our work could help to set up more dedicated experiments to further tackle a technologically relevant issue for the applications of MoS2‐based lubricants.
Selective Hydrogenation of Nitriles to Primary Amines by using a Cobalt Phosphine Catalyst
Authors: Adam Rosa , Bheeter Charles Beromeo , Cabrero‐Antonino Jose R. , Junge Kathrin , Jackstell Ralf , Beller Matthias 
Published: January 2017

AbstractA general procedure for the catalytic hydrogenation of nitriles to primary amines by using a non‐noble metal‐based system is presented. Co(acac)3 in combination with tris[2‐(dicyclohexylphosphino)ethyl]phosphine efficiently catalyzes the selective hydrogenation of a wide range of (hetero)aromatic and aliphatic nitriles to give the corresponding amines.
Uterine Perforation by Intra‐uterine Contraceptive Devices and their Laparoscopic Removal
Authors: Zuhair A. , Buckle A. E. R. 
Published: January 2017

ABSTRACTThe clinical features of 14 cases of uterine perforation by an intra‐uterine contraceptive device (IUCD) are described. In all but one instance the device was removed via the laparoscope. Reasons for perforation are discussed and methods of avoiding this complication suggested.
An Assessment of the Side Effects of Switching from One Oral Contraceptive to Another
Authors: Edelman David A. , Kothenbeutel Robert , Levinski Mary Jo , Talwar Prem P. 
Published: January 2017

Edelman, D. A., Kothenbeutel, R., Levinski, M. J. and Talwar, P. P. (IFRP, Triangle Park, NC and Planned Parenthood Clinic of Seattle, Seattle, Wash., USA). An assessment of the side effects of switching from one oral contraceptive to another.Int J Gynaecol Obstet 14: 397–400, 1976.Side effects associated with three oral contraceptives were evaluated in a study in which women were switched to Norlestrin 1 from either Ovral (64 subjects) or Norinyl 1/50 (26 subjects). In the cycle prior to crossover, breast discomfort was more frequent among Norinyl users than among Ovral users. The prevalence of all other reported side effects was not significantly different for Norinyl and Ovral. The crossover to Norlestrin did not significantly change the numbers of patients reporting side effects. By the end of the third Norlestrin cycle, rates of all side effects were similar for women who were switched from either Ovral or Norinyl.
Pyometra
Authors: Karpathios S. , Prevedourakis C. , Papadias C. , Lolis D. 
Published: January 2017

Karpathios, S., Prevedourakis, C., Papadias, C. and Lolis, D. (2nd Dept. of Obstetrics and Gynecology, Aretaieion Hospital, University of Athens, Athens, Greece). Pyometra.Int J Gynaecol 14: 477–479, 1976.Thirteen cases of pyometra without preoperative diagnosis in which vaginal or abdominal surgery was performed, are analysed in the present paper. The histologic examination revealed endocervicitis in all cases, while positive cultures for bacteria were found preoperatively in only eight of the above cases, thus, pyometra was considered to be a symptom of obstruction of the cervical canal.