bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Students Awareness, Access and Utilization of Artificial Intelligence (AI) in Architectural Design
Authors: Cheche Kalu Kalu , Johnson Egwu Oyim , Odom Christopher U. , Eguzouwa Chinemerem Uchechukwu 
Published: October 2024

Artificial intelligence has become a trending topic in the last decade and has permeated all spheres of life and profession and Architecture is no exception. The use of artificial intelligence in architecture is still in its infancy as more research is still being carried out in the application of artificial intelligence in architecture to solve problems ranging from intelligent material design to architectural plan solutions. This study aimed to examine students’ levels of awareness, access, and use of artificial intelligence in architectural design at selected tertiary institutions in Southeast Nigeria. The three tertiary institutions selected are; The Department of Architectural Technology, Akanu Ibiam Federal Polytechnic Unwana, The Department of Architectural Technology Abia State Polytechnic, Aba and The Department of Architecture, Abia State University, Uturu. The main objective is to carry out a survey to investigate the awareness, access, and utilization of artificial intelligence (AI) in architectural design among students in selected tertiary institutions in Southeast Nigeria. This study adopted a descriptive research design of the survey method and employed a three-sectioned questionnaire to elicit information from the respondents. The sample size included a multistage sample of 300 undergraduates across three tertiary institutions in Ebonyi State and Abia State. The findings of the study were that the majority of the students are not aware of artificial intelligence and will use AI if they are aware of it and have access to it for their architectural design. Therefore, there is a need for integrating AI-related courses and workshops into the Architectural curriculum which can lead to better-prepared graduates who are proficient in using advanced design tools, potentially increasing their employability and innovation in the field. This study concluded that students' ability to explore digital resources such as AI for Architectural design is dependent on their awareness and access to digital technologies. A lack of these will result in a lack of use and lack of skill to use them.
Education Infrastructure for Inter-organizational University Collaborations
Authors: Linse Charlotta , Lilliesköld Joakim , Gulliksen Jan , Petersson Joakim 
Published: October 2024

Collaboration is a long and strong academic tradition. Over the years we have seen many investments in increasing collaborations, nationally and internationally, such as Erasmus +, EIT etc. Many of these attempts fall short, there are some collaborations, some development of platforms/infrastructure, but as soon as funding ends, collaboration ends. This paper makes a strong argument for a structured approach to inter-organizational university collaborations where the opportunities and challenges of different alternatives are evaluated. The paper proposes that solutions for national inter-organizational university collaborations can be designed by combining the choice of technical educational platforms with an idea for how to organize the collaborative processes.
We argue that it is possible to stake out the overall approach for inter-organizational university collaborations. Learning from previous initiatives, there are three main alternatives to choose from; (1) Focus on creating organizational collaborations; (2) Focus on creating and sharing content; and (3) Focus on creating common delivery of courses. It is noteworthy to mention that these are not mutually exclusive alternatives but can and should be combined.
A EVOLUÇÃO LEGISLATIVA DA ALIENAÇÃO FIDUCIÁRIA DE BENS MÓVEIS EM FRENTE ÀS AÇÕES DE BUSCA E APREENSÃO À LUZ DA JURISPRUDÊNCIA.
Authors:   Edilson Vitorelli Diniz Lima, Barbosa Pedro Fior 
Published: October 2024

A alienação fiduciária é um instrumento contratual de garantia real que viabiliza a transferência de uma bem móvel para a garantia do pagamento de uma dívida. O objetivo da presente monografia é analisar a evolução normativa do instrumento jurídico de alienação fiduciária, verificando desde os marcos regulatórios das leis especiais até os entendimentos jurisprudências que serviram como norte para a interpretação das leis, cujas quais eram omissas ou imprecisas com relação aos aspectos práticos dos desafios trazidos pelos casos concretos de execução da garantia em frente ao inadimplemento dos devedores. Por consequência foi analisado as contradições entre os tribunais em sede de recursos que basearam a necessidade de melhor interpretação pelo Supremo Tribunal de Justiça, para que este uniformizasse as decisões proferidas pelos tribunais, no que diz respeito à interpretação da lei. Para viabilizar o estudo, foram utilizadas fontes bibliográficas, como livros e em especial as jurisprudências no site do Supremo Tribunal de Justiça. Como resultado, foi verificado que apesar de inúmeras interpretações já existentes a respeito dos dispositivos da lei, em virtude de tratar-se de um diploma jurídico muito antigo, este ainda está aberto a mais interpretações ao decorrer das alterações das necessidades humanas e do cenário social.
Exploring the Impact of Paternal B12 Levels During the Periconceptional Period on IUI Success
Authors: Atea Mouroge Khalaf , Al-Anbari Laith Amer 
Published: October 2024

Background: The present study is a novel exploration of the effects of vitamin B12 supplementation on seminal fluid parameters and the outcomes of intrauterine insemination (IUI). Specifically, we aimed to evaluate the concentrations of vitamin B12 in blood and seminal plasma before and after two months of supplementation.
Objectives: investigate the effects of vitamin B12 supplementation on the characteristics of seminal fluid parameters and IUI outcomes.
Material and Methods: A randomized controlled experiment with 100 randomly selected infertile couples. The patients were divided into two equal groups according to their vitamin B12 dosage. Group A consists of 50 couples who are taking B12 supplements. Obtain blood and seminal plasma samples from couples to measure the level of vitamin B12. Group B consists of 50 couples and does not include any supplements. The couples in group B initiated ovulation induction and intrauterine insemination (IUI) during the same month as the medical examination without the use of any additional supplements. Still, after two months of vitamin B12 supplement, group A started ovulation induction.
Result: Basal semen parameters for sperm count, sperm motility in grades, and sperm morphology in the study group have a higher sperm count than the control group. Vitamin B12 intake for two months improves sperm morphology and increases sperm motility in grades A and B, according to the current study. This has a favorable effect on sperm count overall.
Conclusion: research will determine the positive effect of vitamin B12 supplements on sperm parameters and IUI results.
Efficacy of Bone Anchored Pendulum Appliance Over Conventional Pendulum Appliance during Molar Distalization in the Orthodontic Management of Class II Malocclusion : A Systematic Review
Authors: Vas Nazleen Valerie , R Navaneethan 
Published: October 2024

Background: Pendulum appliance used commonly used to achieve molar distalization in the management of borderline class II malocclusion is associated with mesial tipping of the maxillary premolars and proclination of maxillary incisors post-distalization, resulting in round tripping and increased treatment time. Bone Anchored Pendulum Appliance (BAPA) is one of the modifications of the pendulum that could effectively prevent anchorage loss. Aim: To evaluate the effectiveness of Bone Anchored Pendulum Appliance(BAPA) over the Conventional Pendulum Appliance(CPA) for the distalization of maxillary molar in the management of Class II malocclusion. Materials and Methods: A web search was done in Google Scholar, MEDLINE, Web of Science, LILAC and COCHRANE Library databases using PRISMA guidelines. The search included RCTs and Non RCTs (Both Prospective and Retrospective studies) comparing distalization achieved by BAPA with CPA in Class II malocclusion. The Risk of bias was assessed using the ROBINS - I tool. Results: Of the initial 745 articles, 5 studies met the inclusion criteria and were included to the systematic review. The BAPA showed between 4.8 -6.4 mm of molar distalization and between 9 °-11.3° of distal tipping of molars while the distalization achieved with CPA was between 2mm -6.4mm with 6.67° -14.50° of distal tipping. While CPA groups showed mesial tipping of premolars, distal tipping of premolars was observed with the BAPA appliances. Conclusions: BAPA were found to significantly reduce anterior anchorage loss, distalise the premolars and molars. There is moderate evidence that BAPA provides greater distalization with reduced incidence of unwanted tooth movements.
Toxoplasma Gondii In Association with TLR4 Among Regular Hemodialysis Patients
Authors: Salih Haleema Salman , Abbas Ahmed Abdul-Hassan 
Published: October 2024

Background: Hemodialysis patients can be considered immunocompromised as they have an increased risk of infections.
The activity of Toll -like receptors in defense against infections was observed particularly for Toll like receptor4 molecule. Several single-nucleotide polymorphisms (SNPs) residing in genes encoding Toll -like receptors were reported as significant genetic modifications associated with infections.
Aim: To determine the association between Toll- like receptors 4 polymorphisms and the susceptibility to infection with Toxoplasma gondii in hemodialysis patients.
Materials and Methods: This case- control study was conducted on 150 patients with hemodialysis and 150 apparently healthy blood donors as control group, the samples were collected in the period from march 2021 to November 2021 from Al-Karama hospital and Al-Yarmouk Teaching Hospital. All patients were investigated for the presence of Toxoplasma gondii and Abs (IgG, IgM) by using ELISA technique and conformation by molecular technique (Real time-PCR). The selected SNPs in Toll- like receptors 4 were amplified by using conventional polymerase chain reaction PCR and then sequencing there polymorphism.
Results: In the current study the comparison of median age between patients and controls was with no significant difference, while the laboratory tests revealed significant difference in median level of urea, creatinin , calcium , potassium ,albumin and hemoglobin, and insignificant difference for body mass index and sodium between studied groups.
The ratio of females infected with Toxoplasma gondii was higher than infected males.
The seropositive result in patients for Toxoplasma gondii - IgG and IgM was 15 and 6 respectively while 19 patients were positive by PCR.
However in control group there were 8 patients seropositive for IgG and positive in PCR results while the results of IgM and PCR were negative for all control group.
The Polymerase chain reaction (PCR) products of Toll- like receptors 4 genes were subjected for direct sequencing by using Bio edit software. And the resultant sequences were compared with reference sequences in NCBI. The analysis of TLR-4 rs4986790 genotypes were 24(80%) AA and 6(20%) AG in patients while 6 (60%) AA and 4(40%) AG in controls with insignificant difference, while the analysis of TLR-4 rs4986791 genotypes were 24(80%) CC and 6 (20%) CT in patients while 6 (60%) CC and 4(40%) CT in controls with insignificant difference. Conclusion: There was no significant association of Toxoplasma gondii with TLR4 genotypes of rs4986790 and rs4986791 SNPs in hemodialysis patients.
Neuromiotonía ocular (NMO) post radioterapia
Authors: Ebner Roberto 
Published: October 2024

Objetivo: Se presenta un caso de miotonía ocular tres décadas después de cirugía de la región selar seguida de radioterapia.
Caso clínico: Una paciente de 52 años refiere diplopía inconstante que aparece pocos años antes de la consulta. Si bien presentaba paresia residual del IIIer par craneal derecho post operatorio, la diplopía que refiere es nueva y no se comporta como las ocasionadas por afección de la placa neuro-muscular ni por una nueva masa selar u otras patologías asociadas. El estudio de neuroimágenes específicas para nervios craneales permitió demostrar la presencia de edema del tercer nervio afectado. Se instauró tratamiento con estabilizadores de membrana y aplicación de toxina botulínica en recto medio del OD para proveer solución a este tipo de diplopía.
Conclusión: La neuromiotonia es una situación infrecuente en pacientes irradiados luego de cirugía de la región selar. La aparición temprana o tardía de diplopía inconstante lleva al diagnóstico de NMO, luego de descartar miastenia, presencia de nueva masa selar y otras, mediante evaluación neurooftalmologica e imágenes adecuadas.
Analisa Stabilitas Perbaikan Dinding Penahan Tanah Eksisting pada Proyek Dermaga Veem Terminal Kalianget Kabupaten Sumenep
Authors: Firatama Aditya Dandy , Aziz Hafif Ahmad Abdul , Rokhmawati Yuni 
Published: October 2024

Dermaga Kalianget memiliki peranan penting dalam mendukung aktivitas pelayaran, termasuk pengiriman barang di daerah Kabupaten Sumenep. Terdapat rencana perbaikan sisi timur dermaga dengan perkuatan dinding penahan tanah beton yang akan diperkuat Corrugated Concrete Sheet Pile dan penambahan pile cap baru. Penelitian ini bertujuan untuk mengetahui staibilitas perbaikan dinding penahan tanah eksisting pada proyek dermaga veem terminal Kalianget dan mendapatkan desain efisien serta aman dengan menggunakan metode kuantitatif pendekatan finite element methode program bantu PLAXIS 2D sehingga didapatkan nilai safety factor yang ditinjau secara global serta gaya dalam yang terjadi. Dari hasil analisa stabiltas perbaikan dinding penahan tanah Dermaga Kalianget dengan meninjau beberapa metode alternatif perbaikan direkomendasikan 2 metode yaitu perbaikan Alternatif 1 (CCSP dengan perkuatan Angkur Pile) dan perbaikan Alternatif 3 (SPSP dengan perkuatan Angkur Pile). Dari kedua metode alternatif perbaikan telah memenuhi nilai minimum stabilitas dinding penahan tanah, sehingga desain tersebut aman untuk dilaksanakan.
The impact of combined application of biochar and fertilizer on the biochemical properties of soil in soybean fields
Authors: Zhang Mingcong , Xie Wei , Zhong Xingjie , Wang Yuqing , Li Siyan , Zhou Yanhong , Wang Chen 
Published: October 2024

Background
Heilongjiang Province is a major soybean production area in China. To improve soil structure and increase soybean yield, this study examined the effects of combined biochar and chemical fertilizer application on the biochemical properties of soil in a maize-soybean rotation system.

Methods
The research were conducted from 2021 to 2022 at Heshan Farm Science Park in Heilongjiang Province, this field plot experiment utilized two soybean varieties, Heihe 43 (a high-protein variety) and Keshan 1 (a high-oil variety). In 2021, two plots with similar fertility levels were selected for planting soybeans and maize. In 2022, a maize-soybean rotation was implemented with five treatments: conventional fertilization (CK), increased biochar+reduced fertilizer 1 (F1+B), reduced fertilizer 1 (F1), increased biochar+reduced fertilizer 2 (F2+B), and reduced fertilizer 2 (F2). The study systematically analyzed the effects of combined biochar and chemical fertilizer application on soil chemical properties and microbial characteristics.

Results
Over 2 years, results showed that combined application effectively improved soil chemical traits. Compared to conventional fertilization (CK) and reduced fertilization (F1, F2), t he combined application of biochar and chemical fertilizer (F1+B, F2+B) increased soil pH, EC and the absolute value of zeta potential of soil surface, the CEC of soil significantly increased by 15.6–44.3%, the soil surface charge density and the soil surface charge quantity significantly increased by 16.4–73.5%. The combined application of biochar and chemical fertilizer also effectively enhanced the abundance and diversity of soil microbes. Dominant bacterial groups in soybean field soils under different treatments included Actinobacteria, Acidobacteria, Chloroflexi, and Proteobacteria; while dominant fungal groups were Ascomycota, Basidiomycota, and Mortierellomycota. Alpha and Beta diversity analyses revealed that the F1+B treatment significantly enhanced the species richness and diversity of bacteria and fungi in the soil, increasing the proportion and evenness of dominant and beneficial genera.
ALKBH5 modulation of ferroptosis in recurrent miscarriage: implications in cytotrophoblast dysfunction
Authors: Qin Chuanmei , Wu Jiayi , Wei Xiaowei , Liu Xueqing , Lin Yi 
Published: October 2024

Background
As one of the most common and abundant internal modifications of eukaryotic mRNA, N6-methyladenosine (m6A) modifications are closely related to placental development. Ferroptosis is a newly discovered form of programmed cell death. During placental development, placental trophoblasts are susceptible to ferroptosis. However, the interactions of m6A and ferroptosis in trophoblast physiology and injury are unclear.

Methods
Recurrent miscarriage (RM) was selected as the main gestational disease in this study. Published data (GSE76862) were used to analyze the gene expression profiles in patients with RM. The extent of m6A modification in total RNA of villous tissues between patients with RM and healthy controls (HC) was compared. ALKBH5 (encoding AlkB homolog 5, RNA demethylase) was selected as the candidate gene for further research. Quantitative real-time reverse transcription PCR, western blotting, and immunohistochemistry (IHC) confirmed the elevated expression of ALKBH5 in the cytotrophoblasts of patients with RM. Then, cell counting kit-8 assays, glutathione disulfide/glutathione quantification, 2′,7′-dichlorfluorescein-diacetate staining, and malonaldehyde assays were used to explore the alterations of ferroptosis-related characteristics following RAS-selective lethal (RSL3) stimulation after overexpression of ALKBH5. Thereafter, we re-analyzed the published RNA sequencing data upon knockdown of ALKBH5, combined with published tissue RNA-seq data, and FTL (encoding ferritin light chain) was identified as the ferroptosis-related gene in cytotrophoblasts of patients with RM that is regulated by ALKBH5. Finally, western blotting and IHC confirmed the increased expression of FTL in the cytotrophoblasts from patients with RM.

Results
Total m6A levels were decreased in patients with RM. The most significant differentially m6A-related gene was ALKBH5, which was increased in patients with RM. In vitro cell experiments showed that treatment with RSL3 resulted in increased cell death and upregulated ALKBH5 expression. Overexpression of ALKBH5 alleviated RSL3-induced HTR8 cell death and caused decreased levels of intracellular oxidation products. Published transcriptome sequencing revealed that FTL was the major ferroptosis-related gene regulated by ALKBH5 in the villous tissues of patients with RM. Consistent with the expression of ALKBH5, FTL was increased by RSL3-induction and increased in patients with RM.

Conclusion
Elevated ALKBH5 alleviated RSL3-induced cytotrophoblast cell death by promoting the expression of FTL in patients with RM. Our results supported the view that ALKBH5 is an important regulator of the ferroptosis-related etiology of RM and suggested that ALKBH5 could be responsible for epigenetic aberrations in RM pathogenesis.
The effect of multi-directional sprint training on change-of-direction speed and reactive agility of collegiate tennis players
Authors: Zhou Zhihui , Xin Chenxi , Zhao Yue , Wu Haijun 
Published: October 2024

Objective
The aim of this study was to evaluate the effect of random route multi-directional sprint training (MDST) compared to fixed route MDST on change-of-direction speed (CODS) and reactive agility (RA), and to investigate the correlation between CODS, RA and short-distance straight sprint speed (SDSS).

Method
A total of 19 collegiate tennis players from Beijing Sport University were randomly assigned to either the random route MDST group (RR group, N = 9, age: 22.22 ± 2.22 years) or the fixed route MDST group (FR group, N = 10, age: 21.90 ± 1.66 years). Both groups completed a progressive load intervention training for 3 weeks, three times a week. The RR group’s random route, mirroring the distance and number of change-of-direction (COD) in the FR group’s fixed route, was specifically designed. The spider run, T-drill, RA test and 5-m straight line sprint test were performed before and after the intervention.

Results
Both groups showed improved performance in the spider run (p < 0.05), T-drill (p < 0.01) and 5-m straight (p < 0.001) line sprint test after the intervention. Additionally, there was no significant difference in the improvement of CODS and SDSS between the two groups (p > 0.05). The RA of the RR and FR groups after the intervention was significantly higher than before intervention (p < 0.001), and RR group showed greater improvement in RA compared to the FR group. There was a moderate correlation between spider run and T-drill (r = 0.523), RA (r = 0.388), and no significant correlation between spider run and 5-m straight sprint (p > 0.05). T-drill was moderately correlated with RA (r = 0.347) and 5-m straight sprint (r = 0.321). RA was moderately correlated with 5-m straight sprint (r = 0.551).

Conclusion
Three-week multi-directional sprint training can effectively improve the change-of-direction speed, reactive agility and short-distance straight sprint speed of collegiate tennis players. And random route multi-directional sprint training has better effect on improving reactive agility.
The relationship between allergic rhinitis and attention deficit hyperactivity disorder: a systematic review and meta-analysis
Authors: Wang Qian , Wang Ruikun , Li Mengyao , Liang Jieqiong , Zhan Xiaojun , Lu Yingxia , Huang Guimin , Gu Qinglong 
Published: October 2024

Background
Numerous investigations have examined the potential link between allergic rhinitis (AR) and attention deficit hyperactivity disorder (ADHD). However, some studies show no association between the two diseases. The connection between these two conditions remains inconclusive. This study aimed to conduct a meta-analysis exploring the correlation between AR and ADHD.

Methods
We conducted systematic searches of the MEDLINE, EMBASE, Cochrane Library, ERIC, PubMed, Web of Science, and CINAHL databases, up to the year 2023. Subsequently, we conducted a meta-analysis using R 4.2.2, where we computed the pooled odds ratio with a 95% confidence interval to assess the relationship between AR and ADHD within studies exhibiting similar characteristics. Statistical heterogeneity was evaluated by computing the value using the Cochrane Intervention Manual’s guidelines. Additionally, subgroup analyses were conducted by stratifying the study population according to gender, age, etc. Sensitivity analysis was performed by systematically removing individual studies.

Results
In this systematic review, we incorporated 12 eligible studies, collectively encompassing a sample size of 530,360 participants. Within the included studies, heterogeneity was observed, and the utilization of a random-effects model demonstrated a noteworthy correlation between children with ADHD and the presence of AR. Similarly, children with AR exhibited a significant correlation with the occurrence of ADHD. We also found some relationships in subgroup analyses.

Conclusion
A substantial correlation is evident between AR and ADHD in children and adolescents. AR may potentially contribute as a risk factor for the onset of ADHD, and conversely, ADHD may heighten the likelihood of developing AR.