bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epigallocatechin-3-gallate
Authors: Mahajan Deepak , Bhat Z.F. , Kumar Sunil 
Published: April 2017

Purpose
The purpose of the study was to explore the possibility of utilization of epigallocatechin-3-gallate (EGCG) as a novel preservative in cheese. EGCG has strong antioxidant and antimicrobial properties and may be commercially exploited as a natural antioxidant and preservative in cheese like products which are highly susceptible to lipid oxidation.

Design/methodology/approach
The study was conducted to evaluate the possibility of using EGCG as a natural antioxidant and preservative in cheese. Kalari, a hard and dry cheese, was used as a model and treated with different concentrations of EGCG (0, 0.05 and 0.10 per cent) and aerobically packaged within low-density polyethylene pouches and assessed for oxidative stability and storage quality under refrigerated (4 ± 1°C) conditions.

Findings
EGCG showed a significant (p < 0.05) effect on the lipid oxidative stability as the treated products exhibited significantly (p < 0.05) lower thiobarbituric acid reactive substances (milligram malonaldehyde/kg) values. A significant (p < 0.05) effect was also observed on the microbiological characteristics of the products, as treated products showed significantly (p < 0.05) lower values for total plate count (log cfu/g), psychrophilic count (log cfu/g), yeast and mould count (log cfu/g) and free fatty acid (% oleic acid) values. Coliforms (log cfu/g) were not detected throughout the storage period. Significantly (p < 0.05) higher scores were observed for various sensory parameters of the treated products. EGCG successfully improved the oxidative stability and storage quality of Kalari.

Originality/value
The results suggest that EGCG might be useful to the dairy industry as an efficient alternative to synthetic antioxidants and preservatives.
Deformation behaviour of Sn-3.0Ag-0.5Cu (SAC305) solder wire under varied tensile strain rates
Authors: Abdullah Izhan , Zulkifli Muhammad Nubli , Jalar Azman , Ismail Roslina 
Published: April 2017

Purpose
The purpose of this paper is to investigate the relationship between microstructure and varied strain rates towards the mechanical properties and deformation behaviour of Sn-3.0Ag-0.5Cu (SAC305) lead-free solder wire at room temperature.

Design/methodology/approach
Tensile tests with different strain rates of 1.5 × 10−6, 1.5 × 10−5, 1.5 × 10−4, 1.5 × 10−3, 1.5 × 10−2 and 1.5 × 10−1 s−1 at room temperature of 25°C were carried out on lead-free Sn-3.0Ag-0.5Cu (SAC305) solder wire. Stress-strain curves and mechanical properties such as yield strength, ultimate tensile strength and elongation were determined from the tensile tests. A microstructure analysis was performed by measuring the average grain size and the aspect ratio of the grains.

Findings
It was observed that higher strain rates showed pronounced dynamic recrystallization on the stress-strain curve. The increase in the strain rates also decreased the grain size of the SAC305 solder wire. It was found that higher strain rates had a pronounced effect on changing the deformation or shape of the grain in a longitudinal direction. An increase in the strain rates increased the tensile strength and ductility of the SAC solder wire. The primary deformation mechanism for strain rates below 1.5 × 10−1 s−1 was grain boundary sliding, whereas the deformation mechanism for strain rates of 1.5 × 10−1 s−1 was diffusional creep.

Originality/value
Most of the studies regarding the deformation behaviour of lead-free solder usually consider the effect of the elevated temperature. For the current analysis, the effect of the temperature is kept constant at room temperature to analyze the deformation of lead-free solder wire solely because of changes of strain rates, and this is the originality of this paper.
Can smartphones measure momentary quality of life and participation? A proof of concept using experience sampling surveys with university students
Authors: Liddle Jacki , Wishink Anna , Springfield Liz , Gustafsson Louise , Ireland David , Silburn Peter 
Published: April 2017

BackgroundUnderstanding quality of life and participation is a key aspect of occupational therapy research. The use of smartphones to deliver experience‐sampling surveys may provide an accessible way to monitor these outcomes. This study used smartphone‐based experience sampling methods (ESM) to investigate factors influencing momentary quality of life (mQOL) of university students.MethodsA convenience sample of students at an Australian university participated. Using a custom smartphone application, ESM surveys were sent six to eight times, every second day, over a week. Participants indicated their mQOL, occupational participation, occupational enjoyment, social context and location via surveys and provided demographic and health information in a single self‐report questionnaire. The relationship between mQOL and variables was analysed at the survey level using logistic regression.ResultsForty students completed 391 surveys. Higher mQOL was significantly related to participation in productive occupations (z = 3.48; P = 0.001), moderate (z = 4.00; P < 0.001) or high occupational enjoyment (z = 7.06; P < 0.001), being with someone (z = 2.15, P = 0.031), being at home (z = 2.49; P = 0.013) and an excellent self‐rated health status (z = 2.35; P = 0.019). The magnitude of differences in mQOL was small.ConclusionThis study suggests that mQOL amongst university students relates to personal, environmental and occupational factors. The use of smartphone‐based ESM appears to be a practical approach for investigating participation and QOL. Further research utilising a more diverse sample, analysing at the individual level, and using ESM in conjunction with other methodologies is recommended.
The Accuracy of Senior Households’ Estimates of Home Values: Application to the Reverse Mortgage Decision
Authors: Haurin Donald , Moulton Stephanie , Shi Wei 
Published: April 2017

AbstractUsing a unique data set of more than 14,000 senior homeowners in the United States, this study compares self‐assessed home values to arm's length contemporaneous appraisals. In a sample of seniors who received counseling for a reverse mortgage, the absolute value of the assessment error averages 18.9% of appraised value and it is biased upwards by 13.4%. When adjusted to reflect the general population of seniors, the size and bias of the average error fall to 16.1% and 4.2%. Both the bias and the size of the error tend to be lower for households with higher income and credit scores but it is greater for black households. In our sample period of 2009–2011, house prices were falling. The greater the rate of price reduction, the greater is the upward bias and size of the assessment error. When seniors who applied for a reverse mortgage learn that they overvalued their home, their probability of closing the loan falls.
Age Estimation of Infants Through Metric Analysis of Developing Anterior Deciduous Teeth
Authors: Viciano Joan , De Luca Stefano , Irurita Javier , Alemán Inmaculada 
Published: April 2017

AbstractThis study provides regression equations for estimation of age of infants from the dimensions of their developing deciduous teeth. The sample comprises 97 individuals of known sex and age (62 boys, 35 girls), aged between 2 days and 1,081 days. The age‐estimation equations were obtained for the sexes combined, as well as for each sex separately, thus including “sex” as an independent variable. The values of the correlations and determination coefficients obtained for each regression equation indicate good fits for most of the equations obtained. The “sex” factor was statistically significant when included as an independent variable in seven of the regression equations. However, the “sex” factor provided an advantage for age estimation in only three of the equations, compared to those that did not include “sex” as a factor. These data suggest that the ages of infants can be accurately estimated from measurements of their developing deciduous teeth.
Provenance Establishment of Stingless Bee Honey Using Multi‐element Analysis in Combination with Chemometrics Techniques
Authors: Shadan Aidil Fahmi , Mahat Naji A. , Wan Ibrahim Wan Aini , Ariffin Zaiton , Ismail Dzulkiflee 
Published: April 2017

AbstractAs consumption of stingless bee honey has been gaining popularity in many countries including Malaysia, ability to identify accurately its geographical origin proves pertinent for investigating fraudulent activities for consumer protection. Because a chemical signature can be location‐specific, multi‐element distribution patterns may prove useful for provenancing such product. Using the inductively coupled‐plasma optical emission spectrometer as well as principal component analysis (PCA) and linear discriminant analysis (LDA), the distributions of multi‐elements in stingless bee honey collected at four different geographical locations (North, West, East, and South) in Johor, Malaysia, were investigated. While cross‐validation using PCA demonstrated 87.0% correct classification rate, the same was improved (96.2%) with the use of LDA, indicating that discrimination was possible for the different geographical regions. Therefore, utilization of multi‐element analysis coupled with chemometrics techniques for assigning the provenance of stingless bee honeys for forensic applications is supported.
Interactions between general and central obesity in predicting gestational diabetes mellitus in Chinese pregnant women: A prospective population‐based study in Tianjin, China
Authors: Han Qian , Shao Ping , Leng Junhong , Zhang Cuiping , Li Wei , Liu Guifeng , Zhang Yuanyuan , Li Yi , Li Zhe , Ren Yanfeng , Chan Juliana C.N. , Yang Xilin 
Published: April 2017

AbstractBackgroundThe aim of the present study was to define cut‐off points of body mass index (BMI) and waist circumference (WC) for gestational diabetes mellitus (GDM) and to investigate any interactions between high BMI and high WC on the risk of GDM in pregnant Chinese women.MethodsFrom 2010 to 2012, 17 803 women in Tianjin, China, who were at 4–12 weeks gestation were recruited to the study. Gestational diabetes mellitus was diagnosed according to the criteria of the International Association of Diabetes and Pregnancy Study Group at 24–28 weeks gestation. Binary logistic regression was used to obtain odds ratios (ORs) and 95% confidence intervals (CIs) while controlling for the confounding effects of traditional risk factors. Restricted cubic spline was used to identify cut‐off points of WC and BMI, if any, for GDM.ResultsGestational diabetes mellitus developed in 1383 (7.8%) women. The risk of GDM increased steeply with increasing WC from ≥78.5 cm and BMI ≥22.5 kg/m2. If BMI <22.5 kg/m2 and WC <78.5 cm were used as the reference, BMI between ≥22.5 and <24.0 kg/m2 (multivariable OR 1.76; 95%CI 1.47–2.10) and WC between ≥78.5 and <85.0 cm (multivariable OR 1.53; 95%CI 1.31–1.78) were independently associated with increased risks of GDM. In addition, the presence of both BMI ≥22.5 kg/m2 and WC ≥78.5 cm further increased the OR to 2.83 (95% CI 2.44–3.28), with significant additive interaction.ConclusionsBody mass index ≥22.5 kg/m2 and WC ≥78.5 cm measured up to 12 weeks of gestation were independently and synergistically associated with increased risks of GDM in Chinese pregnant women.
Responsible RAD: Striving for best practices in population genomic studies of adaptation
Authors: Lowry David B. , Hoban Sean , Kelley Joanna L. , Lotterhos Katie E. , Reed Laura K. , Antolin Michael F. , Storfer Andrew 
Published: April 2017

AbstractTwo recent articles were written in response to our paper “Breaking RAD: An evaluation of the utility of restriction site associated DNA sequencing scans of adaptation.” While we agree with some of the comments made by the authors of these two response papers, we still believe caution should be employed in RADseq studies that aim to detect loci that contribute to adaptation. In this rebuttal, we evaluate the key points made in these papers, attempt to identify a middle ground and make suggestions for responsibly conducting future studies to understand the genomewide mechanisms of adaptation.
A new promising phylogenetic marker to study the diversity of fungal communities: The Glycoside Hydrolase 63 gene
Authors: Pérez‐Izquierdo L. , Morin E. , Maurice J. P. , Martin F. , Rincón A. , Buée M. 
Published: April 2017

AbstractIn molecular ecology, the development of efficient molecular markers for fungi remains an important research domain. Nuclear ribosomal internal transcribed spacer (ITS) region was proposed as universal DNA barcode marker for fungi, but this marker was criticized for Indel‐induced alignment problems and its potential lack of phylogenetic resolution. Our main aim was to develop a new phylogenetic gene and a putative functional marker, from single‐copy gene, to describe fungal diversity. Thus, we developed a series of primers to amplify a polymorphic region of the Glycoside Hydrolase GH63 gene, encoding exo‐acting α‐glucosidases, in basidiomycetes. These primers were validated on 125 different fungal genomic DNAs, and GH63 amplification yield was compared with that of already published functional markers targeting genes coding for laccases, N‐acetylhexosaminidases, cellobiohydrolases and class II peroxidases. Specific amplicons were recovered for 95% of the fungal species tested, and GH63 amplification success was strikingly higher than rates obtained with other functional genes. We downloaded the GH63 sequences from 483 fungal genomes publicly available at the JGI mycocosm database. GH63 was present in 461 fungal genomes belonging to all phyla, except Microsporidia and Neocallimastigomycota divisions. Moreover, the phylogenetic trees built with both GH63 and Rpb1 protein sequences revealed that GH63 is also a promising phylogenetic marker. Finally, a very high proportion of GH63 proteins was predicted to be secreted. This molecular tool could be a new phylogenetic marker of fungal species as well as potential indicator of functional diversity of basidiomycetes fungal communities in term of secretory capacities.
Dentistry and criminal law
Authors: Khoury BS , Khoury JN 
Published: April 2017

AbstractCriminal law in dentistry, as shaped and moulded by the prevailing views of society, defines what is or is not socially acceptable. It applies in both personal and professional contexts with the intended consequence of protecting the public from unacceptable conduct and potential imbalances of power. At its centre, a patient's consent plays a pivotal role in transforming unlawful conduct into lawful conduct. This literature review considers the current law and the trend of utilizing criminal law in addition to non‐criminal law alternatives of reprimanding clinicians for failure to achieve consent in the course of dental practice. Dentists must appreciate this change and the prosecuting authority's increasing willingness to resort to criminal law.
Leukocyte counts and lymphocyte subsets in relation to pregnancy and HIV infection in Malawian women
Authors: Mandala Wilson L. , Gondwe Esther N. , Molyneux Malcolm E. , MacLennan Jenny M. , MacLennan Calman A. 
Published: April 2017

ProblemWe investigated leukocyte and lymphocyte subsets in HIV‐infected or HIV‐uninfected, pregnant or non‐pregnant Malawian women to explore whether HIV infection and pregnancy may act synergistically to impair cellular immunity.Method of studyWe recruited 54 pregnant and 48 non‐pregnant HIV‐uninfected women and 24 pregnant and 20 non‐pregnant HIV‐infected Malawian women. We compared peripheral blood leukocyte and lymphocyte subsets between women in the four groups.ResultsParturient HIV‐infected and HIV‐uninfected women had more neutrophils (each P<.0001), but fewer lymphocytes (P<.0001; P=.0014) than non‐pregnant women. Both groups had fewer total T cells (P<.0001; P=.002) and CD8+ T cells (P<.0001; P=.014) than non‐pregnant women. HIV‐uninfected parturient women had fewer CD4+ and γδ T cells, B and NK cells (each P<.0001) than non‐pregnant women. Lymphocyte subset percentages were not affected by pregnancy.ConclusionMalawian women at parturition have an increased total white cell count due to neutrophilia and an HIV‐unrelated pan‐lymphopenia.
Long‐acting recombinant follicle‐stimulating hormone in random‐start ovarian stimulation protocols for fertility preservation in women with cancer
Authors: Sarais Veronica , Paffoni Alessio , Pagliardini Luca , Filippi Francesca , Martinelli Fabio , Mangili Giorgia , Candiani Massimo , Papaleo Enrico 
Published: April 2017

AbstractIntroductionThe objective of this study was to assess the effectiveness and potential benefits of the use of long‐acting recombinant follicle‐stimulating hormone (FSH) in a random‐start protocol for fertility preservation in women with cancer.Material and methodsThis is a retrospective before‐and‐after study performed between February 2013 and December 2015 in women who underwent ovarian hyperstimulation for oocyte cryobanking using a random‐start approach. In the first part of the study period, the women were treated with daily recombinant FSH whereas in the second part the stimulation was initiated with long‐acting recombinant FSH. The primary aim of the study was to compare the number of oocytes stored in the two study periods. In all, 140 women were ultimately selected.ResultsCompared with daily recombinant FSH, the use of the long‐acting compound was associated with a reduced number of injections (12.5 ± 3.5 vs. 16.4 ± 0.3; p < 0.001) and a longer duration of stimulation (11.4 ± 1.9 vs. 10.6 ± 1.9, p = 0.01). Conversely, the number of oocytes collected (13.7 ± 9.5 vs. 11.3 ± 7.0, p = 0.10) as well as those cryopreserved (11.0 ± 8.0 vs. 9.5 ± 5.8, p = 0.21) did not differ.ConclusionsThe use of long‐acting recombinant FSH in random‐start protocols for fertility preservation appears to be a valuable option.
Characteristics, management, and outcomes of patients with follicular dendritic cell sarcoma
Authors: Jain Preetesh , Milgrom Sarah A. , Patel Keyur P. , Nastoupil Loretta , Fayad Luis , Wang Michael , Pinnix Chelsea C. , Dabaja Bouthaina S. , Smith Grace L. , Yu Jun , Hu Shimin , Bueso Ramos Carlos E. , Kanagal‐Shamanna Rashmi , Medeiros L. Jeffrey , Oki Yasuhiro , Fowler Nathan 
Published: April 2017

SummaryDendritic cell sarcomas are rare tumours of antigen presenting cells. Data regarding their biology, management and outcomes are sparse. We analysed 66 patients with follicular dendritic cell sarcoma (FDCS). Six patients also had Castleman disease, 9 had another malignancy and 13 had an autoimmune disease. Fifty‐four per cent of patients presented with localized disease and 46% with systemic involvement. The median progression‐free (PFS) and overall survival (OS) following frontline therapy was 21 and 50 months, respectively. Survival outcomes were significantly inferior in patients with extranodal, bulky or intra‐abdominal disease at presentation. Stage was not associated with survival. Management approaches were heterogeneous. Patients who underwent an upfront gross total resection (GTR) experienced better PFS and OS (both P < 0·0001). In patients who underwent a GTR, consolidative radiotherapy was associated with improved local control (P = 0·03), PFS (P = 0·04) and OS (P = 0·05). In patients with measureable disease, gemcitabine with a taxane yielded an overall response rate of 80%. The pattern of relapse was predominantly locoregional. Salvage rates after recurrence were poor. Studies are underway at our institution to define the genomic profile in FDCS and identify potential novel therapeutic targets.
Glacial geomorphology of the Northeast Newfoundland Shelf: ice‐stream switching and widespread glaciotectonics
Authors: Shaw John , Longva Oddvar 
Published: April 2017

Analysis of Olex bathymetry, multibeam sonar and seismic survey data, shows that, perhaps during the mid Pleistocene, grounded ice crossing the Northeast Newfoundland Shelf was topographically steered in Hawke Saddle, occupied a broad trough underlying much of Belle Isle Bank and present‐day Notre Dame Trough, and deposited ~100 m of stacked glacigenic sediment; grounded ice crossed southern Funk Island Bank and occupied Notre Dame Trough. During the Wisconsinan Stage, c. 30 cal. ka BP, flow remained topographically steered in Hawke Saddle, but due to flow switching two convergent ice streams incised the stacked sediments of the earlier phase, creating the modern Notre Dame Trough, and diverging around an erosional remnant near the shelf edge. The ice margin at the Last Glacial Maximum (c. 18 14C ka BP) was at the shelf edge in Trinity Trough but far to the west elsewhere. Retreating ice did not stabilize at fjord mouths, but halted several times within fjords. Shelf morphology was shaped by glaciotectonism. The large tectonized zone on the north flank of Notre Dame Trough was created by the northernmost of the two convergent streams. Glaciotectonism was most widespread in the enclosed St. Anthony Basin, where the Quaternary cover has been stripped away, arrays of composite ridges have formed and sediment blocks have been thrust onto the adjacent bank. A large hill‐hole pair was formed on the east side of the basin, extending onto Belle Isle Bank. A hill‐hole pair on the inner shelf was formed by ice flow from the northwest into Notre Dame Channel. Evidence of widespread glaciotectonism distinguishes this relatively deep shelf from the adjoining, relatively shallow, eastern Canadian shelves, but has strong parallels with parts of the Norwegian continental shelf where methane hydrates maybe played a role in regulating ice‐stream flow.
Factors influencing pre‐operative urinary calcium excretion in primary hyperparathyroidism
Authors: Kaderli Reto M. , Riss Philipp , Geroldinger Angelika , Selberherr Andreas , Scheuba Christian , Niederle Bruno 
Published: April 2017

SummaryObjectiveNormal or elevated 24‐hour urinary calcium (Ca) excretion is a diagnostic marker in primary hyperparathyroidism (PHPT). It is used to distinguish familial hypocalciuric hypercalcaemia (FHH) from PHPT by calculating the Ca/creatinine clearance ratio (CCCR). The variance of CCCR in patients with PHPT is considerable. The aim of this study was to analyse the parameters affecting CCCR in patients with PHPT.DesignThe data were collected prospectively. Patients with sporadic PHPT undergoing successful surgery were included in a retrospective analysis.PatientsThe analysis covered 381 patients with pre‐operative workup 2 days before removal of a solitary parathyroid adenoma.MeasurementsThe impact of serum Ca and 25‐hydroxyvitamin D3 (25‐OH D3) on CCCR.ResultsThe coefficient of determination (R2) in the multivariable model for CCCR consisting of age, Ca, 25‐OH D3, 1,25‐dihydroxyvitamin D3 (1,25‐(OH)2 D3), testosterone (separately for males and females), intact parathyroid hormone (iPTH) and osteocalcin was 25.8%. The only significant parameters in the multivariable analysis were 1,25‐(OH)2 D3 and osteocalcin with a drop in R2 of 15.4% (P<.001) and 2.4% (P=.006), respectively. Bone mineral densities at the lumbar spine, distal radius and left femoral neck were not associated with CCCR (r=−.08, r=−.10 and r=−0.09).ConclusionsIn multivariable analysis, 1,25‐(OH)2 D3 and osteocalcin were the only factors correlating with CCCR. Vitamin D3 replacement may therefore impair the diagnostic value of CCCR and increase the importance of close monitoring of urinary Ca excretion during treatment.