bluuebunny/crossref_metadata_2025_split huggingface dataset:
Latvian Sports Regulation in Transition: Navigating Historical Evolution and Contemporary Development Trends
Authors: Kameņecka-Usova Marina , Žīdens Jānis , Luika Signe , Donāne Laine , Agapova Olena , Stecenko Ieva , Griķis Ričards 
Published: October 2024

This comprehensive analysis delves into the intricate realm of sports law and policies in Latvia, exploring the historical evolution, administrative framework, and policy landscapes that shape the country's sports sector. The text highlights Latvia's transition from the Centralized Soviet Model to a more autonomous sports system post-independence, reflecting the nation's historical context and pursuit of sporting excellence. It examines the interaction between EU regulations and internal sports governance, emphasizing the balance between market-regulating rules and legitimate sports governance. The study also discusses recent legislative amendments in response to geopolitical events that has shaken the Eastern Europe, such as the Russian invasion of Ukraine, showcasing Latvia's proactive approach to safeguarding national interests and ethical standards in sports. Furthermore, insights into the implementation of National Anti-Doping Regulations underscore Latvia's commitment to maintaining integrity in sports. The administrative framework involving various stakeholders, including governmental bodies and non-governmental organizations, is analysed to provide a holistic view of sports policy planning and stakeholder engagement in Latvia. Overall, this research sheds light on the evolving landscape of sports law in Latvia and the country's efforts to promote athletic development, fair play, and good governance in sports. The findings will contribute to a deeper understanding of the factors and forces shaping the sports sector in the country.
Keywords: sports law and geopolitics, sports governance, sports policies, EU sports law, Latvia
Impacts on Biogenic Carbon Dioxide Emission Fluxes Driven by Generated Numerical-Downscaled Climate Scenarios
Authors: San Jose Roberto , Perez-Camanyo J. L. , Jiménez Gañan Miguel 
Published: October 2024

The aim of this research is to analyze the local impacts (high spatial resolution) of tier 1 CMIP6 climate scenarios (SSP126, SSP245, SSP370 and SSP585) on CO2 biogenic emission fluxes after downscaled climate data over five European regions (national, regional and urban scale) for the period: 2015-2050 using numerical simulations with the WRF/Chem-VPRM tool. VPRM is the Vegetation Photosynthesis and Respiration Model which is coupled with the Weather Research and Forecasting (WRF) model and Chem (Transport). Satellite data is used to derive vegetation indexes used by the VPRM model. The effect of climate is isolated using 2018 (reference year) emissions and land use over the entire simulation period and it is calculated as results of the future simulations minus present (2018). The research is part of the European DISTENDER project, who develops a methodological framework to bring together adaptation and mitigation strategies against the risks of climate change. The increase in temperature leads to higher CO2 emissions from vegetation, as the increase in temperature favors the respiration process of plants. The impacts are spatially and temporally varied and therefore each case study and scenario has its own pattern, with a strong influence on the existing vegetation and local climate
Keywords: Climate change, CO2, biogenic emissions, scenarios, downscaling
FACTORS AFFECTING THE FINANCIAL PERFOMANCE OF AGRICULTURAL COMPANY’S: EVIDENCE FROM THE INDONESIA STOCK EXCHANGE
Authors: Intan Dian Retno , Malau Leo Rio Ependi , Rambe Khoiru Rizqy , Damanik Mario 
Published: October 2024

The Indonesian economy is primarily based on the agriculture sector, even growing when other sectors are down. This role is supported by the existence of agricultural companies that run businesses with profit-oriented goals. The company's ability to generate profits reflects the company's financial performance and is influenced by various factors. Using panel data for the years 2015–2021 from 17 agricultural companies listed on the Indonesia Stock Exchange (IDX), this study aims to determine the influence of internal and external factors on the financial performance of agricultural companies in Indonesia. The results of static panel data regression found that the company's growth and the dummy of the Covid-19 pandemic had a positive and significant effect on the company's financial performance which was proxied through the profitability ratio (ROA). Debt asset ratio (DAR), COGS/sales, and exchange rate have a negative and significant effect on ROA. In general, these results confirm the pecking-order theory in the relationship between ROA and DAR, as well as the ability of agricultural companies in Indonesia to survive in the conditions of the Covid-19 pandemic. The implication for improving the performance of agricultural companies in Indonesia is that companies must be able to reduce the percentage of production costs (COGS/sales) and implement an optimal capital structure mix. Companies are also required to carry out good risk management to anticipate exchange rate fluctuations.
THE SUSTAINABILITY ANALYSIS OF THE CHRYSANTHEMUM FLOWER BUSINESS IN BANDUNGAN SUB-DISTRICT SEMARANG DISTRICT
Authors: Malihatun Ira , Sumekar Wulan , Legowo Anang Mohamad 
Published: October 2024

Chrysanthemums are ornamental plants with the most production in Indonesia in 2021, amounting to 344,031,088 stalks. One of the largest chrysanthemum producers in Indonesia is the province of Central Java. Bandungan District, Semarang Regency is the largest contributor to chrysanthemum production in Central Java. Bandungan District has a harvest area of 1,692,000 m2 and the highest chrysanthemum production of 121,135,000 stalks compared to other districts, but the productivity is low at 71 stalks / m2 and has an impact on the low profits obtained by chrysanthemum flower farmers. The chrysanthemum business in Bandungan District has the potential to continue to be increased. This can be seen from the strategic role of Bandungan District as the main producer of chrysanthemums in Semarang Regency and in Central Java Province. The demand for chrysanthemum flowers in the market is very high, resulting in the growth of the chrysanthemum flower business is increasing. So efforts are needed to realize the sustainability of the chrysanthemum flower business. The study aims to analyze the sustainability of the chrysanthemum business in terms of social, economic and environmental aspects. The number of samples taken was 72 chrysanthemum farmers by proportional randomsampling in three villages which represented the largest land area. Multidimensional Scaling (MDS) analysis with theRapfish approach is used to see the sustainability status of the chrysanthemum business based on three dimensions, namely social, economic and environmental aspects. Based on the results of the study, the status of the social dimension of thesustainability of the chrysanthemum flower business is classified as less sustainable, with a score of 46.53; the status of the economic dimension is classified as good or very sustainable, the value is 88.35; and the status of the environmental dimension is classified as less sustainable, the value is 27.94.
THE IMPACT OF SOCIO-ECONOMIC FACTORS OF HORTICULTURAL FARMERS ON ACCESS TO MICROFINANCE IN EAST JAVA
Authors: Hasbiy Khoirul Umam , Hardana Andrean Eka 
Published: October 2024

Almost all corporate financing in the agriculture sector is dependent on interest. Because the features of the agricultural sector are incompatible with the finance sector, banks often show little interest in funding the agricultural sector. The purpose of this study were Analyze the socio-economics factors that influence the decision of horticultural farmers in East Java in accessing microfinance. The method of determining the location of the research was carried out in two locations, namely Wonomulyo Village, Poncokusumo Subdistrict, Malang Regency, dan Pacet Village, Pacet Subdistrict, Mojokerto Regency. 160 farmers were chosen as the study's sample size using the proportionate stratified sampling technique and the Slovin formula. To answer these problems descriptive analysis, logistic regression analysis (logit) was used. Formal institutions assigned to channel the funds include government banks and private banks. Informal institutions that carry out the distribution of micro-credit funds are the private sector or institutions from the farmers themselves. The majority of farmers generally know that the level of formal financing sources is indeed lower, but administrative procedures are considered difficult. Based on the results of logistic regression analysis for the factors that influence the decisions of Horiculture farmers in East Java in accessing credit, including education, length of business, land area, and income. It is recommended that in order to formulate steps for the ease of taking out agricultural loan, Field Extension Officers, regional cooperatives, government banks, and private banks should conduct specific studies and take specific approaches.
Несколько замечаний к запискам Афанасия Никитина «Хожение за три моря» (XV в.)
Authors: Лифшиц Александр Львович 
Published: October 2024

The paper is devoted to several nonobvious places in the Afanasy Nikitin’s travel notes “Journey Beyond Three Seas” and proposes to revisit their discussion. The first part of the paper deals with toponyms. Thus, it is explained why Afanasy prefers the Arabic toponym Misyur to Egypt. In the next section attempts are made to interpret the doubtful toponym Myar/Myara, which is usually identified with Baku without sufficient justification, although among other toponyms it would be more appropriate to see in this name a distorted Myakka – Mecca. Then a new localization of the country of Shabat and the Shabait shelter of the Indian Sea on the map of the Indian peninsula is proposed, which connects geographical realities with the ethno-political context of the Bengal Sultanate. Further in the article, based on an analysis of the text, an assumption is made about which books might have been lost by Afanasy, on what the traveler’s lamentations about their absence are based, and why they could not have helped Afanasy to celebrate Christian holidays on time. It is proved that Afanasy can be considered as an “unbalanced bilingual,” since the text of the notes reflects the process of his loss of a sense of language. It is justified that the preserved version of the notes was created later, almost at the end of the journey.
Community flood risk assessment in selected areas in Muntinlupa City
Authors: Masanga L.P. , Caballero R.V. 
Published: October 2024

The study's objective is to hopefully create a profound awareness in the city government of Muntinlupa of the plight the community is experiencing. A quantitative research design was utilized in this study. Flood risk perception: The probability of whether a retention pond, increasing the diameter of the existing reinforced concrete pipes, and or increasing the road elevation can be a permanent or a quick-fix solution is still unknown until the local government can conduct a comprehensive technical and environmental assessment of the different vulnerability factors in the community. No significant differences were found between age, years of residency, and flood risk perception. Flood risk preparedness: No significant differences existed between age, years of residency, and flood risk preparedness. Substantial differences were found between gender and flood preparedness, and they favor the male gender. Flood risk awareness: No significant differences existed between age, years of residency, and flood risk awareness. There were substantial differences between gender and flood awareness, and they favored the male gender. The study's recommendations encourage the local government of Muntinlupa to conduct a comprehensive administrative, technical, and environmental assessment of the different vulnerability factors facing the selected areas in the community.
Pengaruh Penambahan Monokalium Fosfat Dan Media Tanam Terhadap Produktivitas Tanaman Mentimun (Cucumis sativus L.) Pada Hidroponik Sistem Tetes
Authors: Hartono Budi , Fanata Wahyu Indra Duwi 
Published: October 2024

Mentimun merupakan komoditas hortikultura yang sering dikonsumsi dan dibudidayakan di Indonesia. Tingkat produksi mentimun di Indonesia mengalami peningkatan dari tahun 2018 hingga tahun 2021, namun pada tahun 2022 produksi mentimun mengalami penurunan. Tahun 2018 produksi ketimun sebanyak 433.931 ton, tahun 2019 sebanyak 435.975 ton, tahun 2020 sebanyak 441.286 ton, tahun 2021 sebanyak 471.941 ton. Pada tahun 2022 produksi akan turun menjadi 444.057 ton (BPS, 2022). Peningkatan produksi mentimun juga dapat menggunakan urban farming yang salah satunya menggunakan sistem hidroponik. Sistem hidroponik sangat membutuhkan media tanam sebagai tempat tumbuhnya sistem perakaran tanaman agar pertumbuhan tanaman lebih maksimal dengan menggunakan media tanam yang tepat. Penelitian ini menggunakan media tanam berupa cocopeat, arang sekam, dan arang kayu. Selain menggunakan media tanam, penelitian ini menggunakan konsentrasi MKP 270 ppm, 420 ppm, dan 570 ppm. Penambahan konsentrasi monopotassium fosfat dengan semua perlakuan tidak berpengaruh terhadap hasil produksi mentimun. Media tanam berpengaruh nyata terhadap semua variabel penelitian kecuali diameter buah. Cocopeat berpengaruh nyata terhadap produksi mentimun dibandingkan dengan media arang sekam dan media arang kayu. Interaksi antara penambahan konsentrasi monopotassium fosfat dan media tanam tidak berpengaruh nyata terhadap produksi mentimun.

Kata Kunci: Mentimun, Hidroponik, Media tanam, MKP
Green Synthesis and Characterization of 4'-Hydroxy-4-Nitro Chalcone using Grinding Techniques
Authors: Susanti VH Elfi , Ariani Sri Retno Dwi , Mulyani Sri , Utomo Suryadi Budi , Wathon Muhammad Hizbul 
Published: October 2024

<p>The challenge of developing environmentally friendly synthesis methods for biologically active compounds remains a significant focus in green chemistry. This study aimed to synthesize 4'-hydroxy-4-nitro chalcone from 4-hydroxyacetophenone and 4-nitrobenzaldehyde using a grinding technique and then characterize the synthesized compounds. The 4'-hydroxy-4-nitro chalcone was synthesized via the Claisen-Schmidt grinding method for 45 minutes at room temperature. The grinding results were extracted with chloroform. The formed crystals were tested for purity by thin-layer chromatography (TLC), and further purification was carried out by recrystallization. The synthesized chalcone was characterized using <strong>FTIR,<sup> 1H</sup>-NMR</strong>, and <strong><sup>13</sup>C-NMR</strong> spectroscopy. The chalcone was also tested for antibacterial activity using the disc diffusion method against <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>. The results showed that 4'-hydroxy-4-nitro chalcone could be successfully synthesized from 4-hydroxyacetophenone and 4-nitrobenzaldehyde using the grinding technique, yielding orangish-white crystals with a 70.63% yield and a melting point of 173°C. Purity was confirmed by TLC, and structural characterization was achieved through <strong>FTIR, <sup>1</sup>H-NMR</strong> and <strong><sup>13</sup>C-NMR</strong> spectroscopy. Antibacterial testing revealed that the synthesized chalcone produced a clear zone diameter of 9.27 mm against <em>S. aureus</em> and 27.88 mm against <em>E. coli</em>. These results indicate that the compound has relatively strong antibacterial activity against <em>E. coli</em> and relatively weak activity against <em>S. aureus</em>. This study demonstrates the effectiveness of the green synthesis method and provides valuable insights into the antibacterial properties of 4'-hydroxy-4-nitro chalcone</p>
Toxicity Test of Ethanol Extract Stelechocarpus Burahol (Kepel) Fruits through Brine Shrimp Toxicity Assay
Authors: Rahmawati Naili , Zakaria Zainul Amiruddin , Sani Mohd. Hijaz Mohd , - Kintoko , Jaziri A.Aziz 
Published: October 2024

Pendahuluan: Stelechocarpus burahol (Kepel) merupakan tanaman yang tumbuh alami di Indonesia. Kepel termasuk dalam famili Annonaceae. Evaluasi terhadap toksisitas ekstrak tanaman ini sangat penting untuk mendukung untuk penelitian selanjutnya. Stelechocarpus burahol mengandung senyawa flavonoid, sebagai antimikroba dan kontrasepsi, selain itu flavonoid mengaktifkan jalur antioksidan yang memberikan efek antiinflamasi. Kontrasepsi yang cocok untuk pria dan wanita harus mampu mencegah pembuahan, murah, tidak memiliki efek samping, sehingga diperlukan tanaman obat alami sebagai agen kontrasepsi (KA) karena aman, murah, memiliki antioksidan, dan antiinflamasi. Brine Shrimp Toxicity Assay terhadap ekstrak etanol tanaman ini telah diuji.
Metode: Desain true eksperimen, sampel terdiri 6 kelompok, dan tiap kelompok terdiri dari 10 nauplii hidup. Konsentrasi ekstrak : 250 ppm, 500 ppm, 750 ppm, dan 1000 ppm. Sepuluh nauplii hidup ditambahkan ke setiap konsentrasi, dan volume akhir disesuaikan menjadi 1 ml menggunakan air laut buatan (35 ppt). Botol kontrol negatif berisi 1 ml air laut buatan, sedangkan botol kontrol positif berisi 50% etanol dalam air laut. Setelah 24 jam, semua botol diperiksa dengan senter/kaca pembesar, dan jumlah nauplii yang bertahan hidup dihitung. Percobaan diulang tiga kali, dan data direpresentasikan sebagai Mean±SD
Hasil: Ekstrak etanol buah Stelechocarpus burahol (EESB) yang diuji toksisitasnya terhadap udang air asin memiliki nilai konsentrasi mematikan 50% (LC50) lebih dari 1000 ppm (2787,225 ppm).
Kesimpulan: Ekstrak etanol buah kepel tidak menimbulkan toksisitas terhadap udang air asin. Oleh karena itu, ekstrak etanol buah kepel dapat dipertimbangkan untuk penelitian lebih lanjut dengan uji akut, subakut, dan antifertilitas.
Overcoming traceability challenge in air quality measurements by developing reference gas mixtures of CO2 in a typical indoor/outdoor range for future relevant IoT technology applications
Authors: AlYami Najji H. , AlOwysi Abdullah S. , M. Ahmed Khaled 
Published: September 2024

High-resolution air quality monitoring using inexpensive sensor systems has attracted a lot of attention in the context of smart cities. However, in order to preserve metrological traceability, these systems must be regularly recalibrated. The necessity of quality control, dependability, and traceability of analytical data has received a lot of attention lately. IoT sensors can also be used to monitor the condition of equipment and ensure that it conforms with safety rules, given the rapid advancement of new technologies and their numerous everyday uses. Therefore, the primary motivation for our study endeavour was to provide reference gas mixtures to calibrate those sensors optimally in the future while keeping traceability to SI units, which is an important and demanding duty of gas standard laboratories at NMIs. Given the significance of metrological issues in the current context, the national measurement and calibration centre (SASO-NMCC) developed the methodology for preparing such primary standard gas mixtures (PSMs) through standardized gravimetric method in order to improve measurement capabilities and provide a level of confidence regarding greenhouse gas standards. Compatibility check, as per ISO 6143:2001, for the gas chromatography thermal conductivity detector (GC-TCD) with respect to the gravimetric assigned values with its associated combined uncertainty is also presented for each produced PSM. The relative expanded uncertainty of the carbon dioxide standard mixture, taking into account the contributions from verification analysis by GC-TCD, was less than 0.7 % for the prepared range of (0.00499 ± 0.00006) to (0.1996 ± 0.000424) mol/mol. This is comparable to the average of 0.25 % relative uncertainties presented on international standards mixtures.
Tumor immune evasion abrogated by COUP-TFII reprogramming of the vasculature
Authors: Zhu Yu , Brulois Kevin , Dinh Thanh , Pan Junliang , Butcher Eugene 
Published: October 2024

Abstract

T cell scarcity in tumor tissues poses a critical challenge to cancer immunotherapy. Here we manipulate the tumor vasculature, an essential regulator of immune cell trafficking, to reinvigorate anti-tumor T cell responses in “cold” tumors. We show that ectopic pan-endothelial expression of COUP-TFII, a master transcription factor for venous development, induces molecular programs of post-capillary venules in tumor endothelium. Venular reprogramming selectively promoted T cell recruitment into tumors, inhibited tumor growth in mouse models of breast and pancreatic cancers, and sensitized tumors to immune checkpoint blockade and adoptive T cell transfer therapies. Mechanistic studies show that enhanced recruitment of anti-tumor T cells and tumor inhibition are mediated by COUP-TFII-induced vascular adhesion receptors. Our study supports a pivotal role of vascular endothelial cells in governing tumor immune evasion, and proposes venular reprogramming as a novel therapeutic strategy to bolster anti-tumor immunity and immunotherapy.
Common genetic variants associated with risk of Parkinson's disease in non-European populations: a PROSPERO registered systematic review based on genome-wide association studies
Authors: Santos Júlio César Claudino dos , Pires Jackson Frederico , Mano Gabriela Braga Cabrera , Goes João Vitor Caetano , Gusmão Camilla Teixeira Pinheiro , Barreto-Vianna André Rodrigues da Cunha , Carlo Ettore José Filippi , Viana Tayenne Nélly de Lucena , Lins Camila de Almeida , Stangherlin Luana , Leitão Renata Ferreira de Carvalho , Junior Howard Lopes Ribeiro , Dias Fabricyo de Faria Esposito 
Published: October 2024

Abstract

Parkinson's disease (PD) is a complex genetic neurodegenerative disorder. Epidemiology genetic discoveries have increased our understanding of the molecular contributors to Parkinson's pathophysiology, especially when associated with the advent of genome-wide association studies (GWAS) technologies in the discovery of the risk linked to common germline genetic variants. A biggest limitation of studies on genetic susceptibility to PD is the lack of information describing the impact of individuals’ ancestry on risk associations, especially in non-European populations. Current genetic data are mainly based on individuals of European origin, particularly those included in the UK biobank project. The effects of these ethical discrepancies can directly impact the discovery of risk variants associated with PD susceptibility and clinical management of PD patients in admixture populations, for example. Thus, we performed a PROSPERO-registered systematic review (#CRD42022368534 and PRISMA checklist) to elucidate the current state of the art about the role of common genetic variants based on GWAS studies in advancing precision medicine for PD susceptibility and pathobiology in multiethnic and non-European populations. Also, we talk about whether there are similarities or discrepancies of these data in relation to genomic data obtained in studies with PD patients of European origin.