bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermal, mechanical, and dielectric properties of aluminum silicate fiber reinforced aluminum phosphate–poly(ether sulfone) layered composites
Authors: Yan Shicheng , Xue Yahong , Yang Yulin , Qi Xiaowen , Song Laizhou , Sun Yingbing 
Published: July 2017

ABSTRACTIn this study, a novel aluminum phosphate (AlPO4) heat‐resistant layer reinforced with aluminum silicate fiber (ASF) was successfully compounded on a poly(ether sulfone) (PES) matrix via the preparation process of high‐temperature heat treatment and vacuum hot‐pressing sintering technique. The influence of the ASF content on the morphology, thermal, mechanical, and dielectric properties of the as‐fabricated aluminum silicate fiber reinforced aluminum phosphate–poly(ether sulfone) (ASF/AlPO4–PES) layered composite was investigated. The results reveal that the incorporation of aluminum silicate fiber/aluminum phosphate (ASF/AlPO4) heat‐resistant layer can significantly improve the thermal stability and mechanical performances of the PES matrix composites. Compared with the pristine PES, the ASF/AlPO4–PES layered composite containing 8.0 wt % ASF exhibited better high‐temperature resistance properties (300 °C) and a lower thermal conductivity (0.16 W m−1 K−1). Furthermore, the dielectric constant and dielectric loss tangent of this PES matrix composite decreased to 2.16 and 0.007, respectively. Meanwhile, the frequency stability of the dielectric properties for the ASF/AlPO4–PES layered composites was remarkably enhanced with increasing ASF addition at frequencies ranging from 102 Hz to 5 MHz. This was attributed to the existence of microscopic pores within the ASF/AlPO4 layer and the strong interfacial bonding between the ASF/AlPO4 layer and the PES matrix. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45542.
D‐Malate decreases renal content of α‐ketoglutarate, a driving force of organic anion transporters OAT1 and OAT3, resulting in inhibited tubular secretion of phenolsulfonphthalein, in rats
Authors: Uwai Yuichi , Kawasaki Tatsuya , Nabekura Tomohiro 
Published: July 2017

Abstractd‐Malate inhibits a Krebs cycle enzyme and the tubular transport of α‐ketoglutarate, an intermediate of the Krebs cycle and the driving force for rat organic anion transporter 1 (rOAT1) and rOAT3 in the kidney. This study examined the effects of d‐malate on the rat organic anion transport system. The uptake of 6‐carboxyfluorescein by HEK293 cells expressing rOAT1 or rOAT3 was not affected by d‐malate and l‐malate. Up to 60 min after the intravenous injection of phenolsulfonphthalein (PSP), a typical substrate of the renal organic anion transporters, as a bolus to rats, 47.1% of the dose was recovered in the urine, and its renal clearance was estimated to be 8.60 ml/min/kg. d‐Malate but not l‐malate interfered with its renal excretion, resulting in the delayed elimination of PSP from plasma. No effect of d‐malate was recognized on creatinine clearance or the expression level of rOAT3 in the kidney cortex. d‐Malate increased the plasma concentration of α‐ketoglutarate. In addition, the compound greatly stimulated the renal excretion of α‐ketoglutarate, implying that d‐malate inhibited its reabsorption. The content of α‐ketoglutarate was significantly decreased in the kidney cortex of rats administered d‐malate. Collectively, this study shows that d‐malate abrogates the tubular secretion of PSP, and the reduction of the renal content of α‐ketoglutarate was proposed to be one of the mechanisms. A relationship between the reabsorption of α‐ketoglutarate and the basolateral uptake of organic anion in the kidney is suggested.
Development and validation of an LC–MS/MS method for the simultaneous quantification of seven constituents in rat plasma and application in a pharmacokinetic study of the Zaoren Anshen prescription
Authors: Zhao Ajing , Zhang Li , Li Rong , Shang Jiao , Yi Huihui , Wang Yuan , Zhang Dian , Wang Shixiang , Fang Minfeng 
Published: July 2017

AbstractA sensitive, specific and accurate liquid chromatography–tandem mass spectrometry (LC–MS/MS) method was developed and validated for the simultaneous determination of seven constituents of the Zaoren Anshen prescription (ZAP) in rat plasma after oral administration of the ZAP: spinosin, salvianic acid A, 6′′′‐feruloylspinosin, protocatechualdehyde, salvianolic acid B, schisandrin and deoxyschisandrin. The plasma samples and the internal standard (IS) sulfamethoxazole were extracted using acetonitrile. Chromatographic separation was performed with an Agilent HC‐C18 column using a gradient elution profile and a mobile phase consisting of 0.01% formic acid in water (A) and acetonitrile (B). The analytes were quantified simultaneously in a single run using an ion trap mass spectrometer operated in the multiple reaction monitoring mode and electrospray ion‐source polarity in the positive and negative modes. The calibration curves for spinosin, salvianic acid A, 6′′′‐feruloylspinosin, protocatechualdehyde, salvianolic acid B, schisandrin and deoxyschisandrin were linear over the concentration ranges of 2.90–1160, 2.50–1000, 1.80–720, 0.65–260, 2.50–1000, 8.00–1600 and 1.30–520 ng/mL, respectively. The intra‐ and inter‐day precisions in terms of relative standard deviation were <18.9%, and the accuracies in terms of relative error were within ±14.2%. Consequently, the proposed method was successfully applied to the pharmacokinetic analysis of these seven major active compounds in rats administered ZAP. These results will facilitate research aiming to predict the effectiveness of the optimal dose of ZAP and might be beneficial for the therapeutic use of ZAP in the clinical setting.
Correlation of Tmax volumes with clinical outcome in anterior circulation stroke
Authors: Seker Fatih , Pfaff Johannes , Potreck Arne , Mundiyanapurath Sibu , Ringleb Peter A. , Bendszus Martin , Möhlenbruch Markus A. 
Published: July 2017

AbstractBackground and PurposeThe recent thrombectomy trials have shown that perfusion imaging is helpful in proper patient selection in thromboembolic stroke. In this study, we analyzed the correlation of pretreatment Tmax volumes in MR and CT perfusion with clinical outcome after thrombectomy.MethodsForty‐one consecutive patients with middle cerebral artery occlusion (MCA) or carotid T occlusion treated with thrombectomy were included. Tmax volumes at delays of >4, 6, 8, and 10 s as well as infarct core and mismatch ratio were automatically estimated in preinterventional MRI or CT perfusion using RAPID software. These perfusion parameters were correlated with clinical outcome. Outcome was assessed using modified Rankin scale at 90 days.ResultsIn patients with successful recanalization of MCA occlusion, Tmax > 8 and 10 s showed the best linear correlation with clinical outcome (r = 0.75; p = .0139 and r = 0.73; p = .0139), better than infarct core (r = 0.43; p = .2592). In terminal internal carotid artery occlusions, none of the perfusion parameters showed a significant correlation with clinical outcome.ConclusionsTmax at delays of >8 and 10 s is a good predictor for clinical outcome in MCA occlusions. In carotid T occlusion, however, Tmax volumes do not correlate with outcome.
Emergent social identities in a flood: Implications for community psychosocial resilience
Authors: Ntontis Evangelos , Drury John , Amlôt Richard , Rubin G. James , Williams Richard 
Published: July 2017

AbstractAlthough the mobilization of pre‐existing networks is crucial in psychosocial resilience in disasters, shared identities can also emerge in the absence of such previous bonds, due to survivors sharing a sense of common fate. Common fate seems to operate in sudden‐impact disasters (e.g., bombings), but to our knowledge, no research has explored social identity processes in “rising‐tide” incidents. We interviewed an opportunity sample of 17 residents of York, United Kingdom, who were involved in the 2015–2016 floods. Using thematic and discourse analysis, we investigated residents' experiences of the floods and the strategic function that invocations of community identities perform. We show how shared community identities emerged (e.g., because of shared problems, shared goals, perceptions of vulnerability, and collapse of previous group boundaries) and show how they acted as a basis of social support (both given and expected). The findings serve to further develop the social identity model of collective psychosocial resilience in rising‐tide disasters. Implications for policy and practice are discussed.
Physical Methods for Dealcoholization of Beverage Matrices and their Impact on Quality Attributes
Authors: Müller Magdalena , Bellut Konstantin , Tippmann Johannes , Becker Thomas 
Published: July 2017

AbstractMembrane‐based and thermal methods to produce non‐alcoholic beverages have been used for many years to remove ethanol from beer and other alcoholic, fermented matrices. The aim of all applied methods is to eliminate the ethanol as selectively as possible. Besides legal regulations and nutritional health benefits, different physical production methods as well as the effects on the aroma composition after different production steps and possibilities for procedural descriptions are elucidated.
CO2 Absorption and Regeneration Using Amines with Different Degrees of Steric Hindrance
Authors: Gómez-Díaz Diego , Navaza José M. , Rodríguez Pablo , Vega Raquel 
Published: July 2017

AbstractThe influence of steric hindrance in amines upon different characteristics in carbon dioxide chemical absorption, namely, absorption rate, carbon dioxide loading, and regeneration degree, has been analyzed. Aqueous solutions of monoethanolamine, 1‐amino‐2‐propanol, and 2‐amino‐2‐methyl‐1‐propanol were used to compare their behavior during carbon dioxide absorption. The presence of one or two methyl groups on the carbon next to the amino group produced changes in the analyzed parameters. In addition, the influences of the gas‐flow rate and amine concentration on the chemical solvent behavior were studied to improve the mass transfer under different experimental conditions.
Development of a Robust Fixed‐Bed Reactor Model for Supercritical Citral Hydrogenation
Authors: Häring Hans , Wilhelm Steffen , Horn Daniel , Haase Stefan 
Published: July 2017

AbstractThe hydrogenation of citral in a fixed‐bed reactor by using supercritical carbon dioxide was studied. A numerical model was set up by using the commercial software Aspen Custom Modeler®. By applying literature experimental data, a parameter estimation for the kinetic parameters was carried out. A good fit was reached with the presented model. Furthermore, a sensitivity analysis was performed. The influence of process pressure, inlet CO2 and H2 concentration, and catalyst particle size on conversion, reactor length, space time yield, yield of the intermediate product 3,7‐dimethyl‐2‐octenal, and pressure drop was investigated.
Catalytic Dehydrogenative Coupling of Hydrosilanes with Alcohols for the Production of Hydrogen On‐demand: Application of a Silane/Alcohol Pair as a Liquid Organic Hydrogen Carrier
Authors: Ventura‐Espinosa David , Carretero‐Cerdán Alba , Baya Miguel , García Hermenegildo , Mata Jose A. 
Published: July 2017

AbstractThe compound [Ru(p‐cym)(Cl)2(NHC)] is an effective catalyst for the room‐temperature coupling of silanes and alcohols with the concomitant formation of molecular hydrogen. High catalyst activity is observed for a variety of substrates affording quantitative yields in minutes at room temperature and with a catalyst loading as low as 0.1 mol %. The coupling reaction is thermodynamically and, in the presence of a Ru complex, kinetically favourable and allows rapid molecular hydrogen generation on‐demand at room temperature, under air, and without any additive. The pair silane/alcohol is a potential liquid organic hydrogen carrier (LOHC) for energy storage over long periods in a safe and secure way. Silanes and alcohols are non‐toxic compounds and do not require special handling precautions such as high pressure or an inert atmosphere. These properties enhance the practical applications of the pair silane/alcohol as a good LOHC in the automotive industry. The variety and availability of silanes and alcohols permits a pair combination that fulfils the requirements for developing an efficient LOHC.
The role of TACC3 in mitotic spindle organization
Authors: Ding Zhi‐Ming , Huang Chun‐Jie , Jiao Xiao‐Fei , Wu Di , Huo Li‐Jun 
Published: July 2017

AbstractTACC3 regulates spindle organization during mitosis and also regulates centrosome‐mediated microtubule nucleation by affecting γ‐Tubulin ring complexes. In addition, it interacts with different proteins (such as ch‐TOG, clathrin and Aurora‐A) to function in mitotic spindle assembly and stability. By forming the TACC3/ch‐TOG complex, TACC3 acts as a plus end‐tracking protein to promote microtubule elongation. The TACC3/ch‐TOG/clathrin complex is formed to stabilize kinetochore fibers by crosslinking adjacent microtubules. Furthermore, the phosphorylation of TACC3 by Aurora‐A is important for the formation of TACC3/ch‐TOG/clathrin and its recruitment to kinetochore fibers. Recently, the aberrant expression of TACC3 in a variety of human cancers has been linked with mitotic defects. Thus, in this review, we will discuss our current understanding of the biological roles of TACC3 in mitotic spindle organization.
Photo‐Chromium: Sensitizer for Visible‐Light‐Induced Oxidative C−H Bond Functionalization—Electron or Energy Transfer?
Authors: Otto Sven , Nauth Alexander M. , Ermilov Eugenyi , Scholz Norman , Friedrich Aleksej , Resch‐Genger Ute , Lochbrunner Stefan , Opatz Till , Heinze Katja 
Published: July 2017

AbstractThe front cover artwork is provided by a team of researchers from the Universities of Mainz and Rostock. The image shows the molecular structure of the CrIII photosensitizer [Cr(ddpd)2]3+ which enables C−H bond activation of tertiary amines through generation of singlet oxygen from air and light. Ultrafast intersystem crossing precludes intermolecular nonselective photoredox reactions and allows a selective photochemical pathway through singlet oxygen formation. Read the full text of the Communication at 10.1002/cptc.201700077.
Phylogenetic conservatism and trait correlates of spring phenological responses to climate change in northeast China
Authors: Du Yanjun , Chen Jingru , Willis Charles G. , Zhou Zhiqiang , Liu Tong , Dai Wujun , Zhao Yuan , Ma Keping 
Published: July 2017

AbstractClimate change has resulted in major changes in plant phenology across the globe that includes leaf‐out date and flowering time. The ability of species to respond to climate change, in part, depends on their response to climate as a phenological cue in general. Species that are not phenologically responsive may suffer in the face of continued climate change. Comparative studies of phenology have found phylogeny to be a reliable predictor of mean leaf‐out date and flowering time at both the local and global scales. This is less true for flowering time response (i.e., the correlation between phenological timing and climate factors), while no study to date has explored whether the response of leaf‐out date to climate factors exhibits phylogenetic signal. We used a 52‐year observational phenological dataset for 52 woody species from the Forest Botanical Garden of Heilongjiang Province, China, to test phylogenetic signal in leaf‐out date and flowering time, as well as, the response of these two phenological traits to both temperature and winter precipitation. Leaf‐out date and flowering time were significantly responsive to temperature for most species, advancing, on average, 3.11 and 2.87 day/°C, respectively. Both leaf‐out and flowering, and their responses to temperature exhibited significant phylogenetic signals. The response of leaf‐out date to precipitation exhibited no phylogenetic signal, while flowering time response to precipitation did. Native species tended to have a weaker flowering response to temperature than non‐native species. Earlier leaf‐out species tended to have a greater response to winter precipitation. This study is the first to assess phylogenetic signal of leaf‐out response to climate change, which suggests, that climate change has the potential to shape the plant communities, not only through flowering sensitivity, but also through leaf‐out sensitivity.
Complete recovery of fulminant peripartum cardiomyopathy on mechanical circulatory support combined with high‐dose bromocriptine therapy
Authors: Horn Patrick , Saeed Diyar , Akhyari Payam , Hilfiker‐Kleiner Denise , Kelm Malte , Westenfeld Ralf 
Published: July 2017

AbstractPeripartum cardiomyopathy (PPCM) is an idiopathic cardiomyopathy presenting with heart failure due to left ventricular systolic dysfunction towards the end of pregnancy or in the months following delivery, where no other cause of heart failure is found. We report a case of a woman with PPCM who developed a critical cardiogenic shock with repeated cardiopulmonary resuscitation. We show for the first time that mechanical circulatory support combined with high‐dose bromocriptine therapy to suppress systemic prolactin levels may serve as an effective therapeutic option in patients with fulminant PPCM and cardiogenic shock. Myocardial cathepsin D was overexpressed in our patient underscoring a potential role of cathepsin D‐induced cleavage of prolactin in the pathophysiology of PPCM.
Post‐translational regulation of antiviral innate signaling
Authors: Zhou Yilong , He Chenxi , Wang Lin , Ge Baoxue 
Published: July 2017

AbstractThe innate immune system initiates immune responses by pattern‐recognition receptors (PRR). Virus‐derived nucleic acids are sensed by the retinoic acid‐inducible gene I (RIG‐I)‐like receptor (RLR) family and the toll‐like receptor (TLR) family as well as the DNA sensor cyclic GMP‐AMP (cGAMP) synthase (cGAS). These receptors activate IRF3/7 and NF‐κB signaling pathways to induce the expression of type I interferons (IFNs) and other cytokines firing antiviral responses within the cell. However, to achieve a favorable outcome for the host, a balanced production of IFNs and activation of antiviral responses is required. Post‐translational modifications (PTMs), such as the covalent linkage of functional groups to amino acid chains, are crucial for this immune homeostasis in antiviral responses. Canonical PTMs including phosphorylation and ubiquitination have been extensively studied and other PTMs such as methylation, acetylation, SUMOylation, ADP‐ribosylation and glutamylation are being increasingly implicated in antiviral innate immunity. Here we summarize our recent understanding of the most important PTMs regulating the antiviral innate immune response, and their role in virus‐related immune pathogenesis.
Quick unreferenced NMR quantification of Squalene in vegetable oils
Authors: Rotondo Archimede , Salvo Andrea , Gallo Vito , Rastrelli Luca , Dugo Giacomo 
Published: July 2017

We present here a simple method for the rapid quantification of squalene in vegetable oils by NMR (Nuclear Magnetic Resonance). The method was validated by adding internal standards to several vegetable oil samples. Quantification was accomplished by exploiting the characteristic resolved signal of terminal methyl groups at 1.67 ppm, which allowed squalene quantification regardless of the hydrophobic matrix. Theoretical principles are fulfilled by the method and, despite the general belief that NMR displays intrinsic low sensitivity, acceptable accuracy (<4%) and reproducibility (<6%) can be reached when squalene is over 2000 ppm, even in “worst case scenarios.” This method may be useful in the continuing efforts to rapidly generate accurate and complete quantitative data suitable for inclusion in the identification labels of vegetable oil products.Practical applications: Unreferenced and accurate quantification of squalene in vegetable oils, was validated here by the analysis of several 1H‐NMR spectra of vegetable oils and of standard doped samples. Moreover, we found that squalene can affect the NMR spectra of other quantifiable species. These data may be useful to produce more accurate and precise analyses of vegetable oil using their 1H‐NMR profiles.Collectively, our data indicate that quantification of squalene in vegetable oils can be easily accomplished by 1H‐NMR, opening new potentialities in NMR‐based fat analysis. The ability of squalene to alter NMR spectra should be taken into account, particularly in oils with a high squalene content, such as Sicilian olive oils.
Spatial variability of ocean fertilizing nutrients in the dust‐emitting ephemeral river catchments of Namibia
Authors: Dansie A.P. , Thomas D.S.G. , Wiggs G.F.S. , Munkittrick K.R. 
Published: July 2017

AbstractResearch into global hot spots of dust emission has focused on exposed fine‐grained sediments in palaeo‐ or ephemeral dryland lake basins including Etosha (Namibia) and Makgadikgadi (Botswana) in southern Africa. Namibia's western ephemeral river valleys are also known to produce dust but have remained largely overlooked as a regionally significant source. Nutrient enrichment of valley sediments and proximity to the South Atlantic suggests aeolian dust could play an important role in ocean fertilization. The fertility of valley dust is dependent on fluvial sediments originating in the upper catchments on the Southern African Central Plateau. In this study we investigate climate, geology, vegetation and land use variability and how these may influence the nitrogen, phosphorus and iron availability in the catchments. We intensely sampled the Huab, Kuiseb and Tsauchab river systems to map the spatial distribution of nutrients from upper catchments to river termini. Samples were analysed for the bioavailable fractions of iron, nitrogen and phosphorus as well as total nitrogen and phosphorus. Results show that the lower valley reaches are sources of aeolian dust enriched in nutrients. Nitrogen levels correlate with precipitation and vegetation levels and phosphorus levels with geology. However, differences in upper catchment sediment nutrient levels were not representative of downstream nutrient differences between valleys. Rather, it is the hydrological and geomorphological processes of the ephemeral river systems that are key for producing the enriched sediments in the lower reaches. We demonstrate that the ephemeral river valleys of western Namibia are an extensive and enriched source of mineral dust that could play a critical role in marine productivity of the southern Atlantic. © 2017 The Authors. Earth Surface Processes and Landforms published by John Wiley & Sons Ltd.