bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Ethics of Research and Teaching in an Age of Big Data
Authors: Lundie David 
Published: September 2024

Big Data, understood as high-volume, high-velocity and/or high-variety information assets that enable insight, decision-making, and process automation (Gartner, 2015), offers both opportunities and challenges in all aspects of human life. As Higher Education serves as preparation not only for economic but also for health, welfare, social and civic participation, these changes are imbricated in many aspects of academic endeavor.
In relation to research ethics, this change represents a normative difference in degree rather than a difference in kind. Data is more messy, more rapid, more difficult to predict and more difficult to identify owners, but the principles of informed consent, confidentiality and prevention of harm apply equally to digital as to traditional research data. Central to applying these principles, however, is the recognition that technologies are not inherently value neutral, and that data collection, aggregation, and its use in decision making can both create and intensify inequities and harms. A data justice approach to research ethics extends concern with voice and authenticity into the digital domain.
The transparency and ethics of our research processes have wider significance, as they determine the creation of new knowledge, and the processes by which this is disseminated to students. Universities provide an important role as gatekeepers to professional accreditation in a number of fields, including software engineering, and the relation between academic freedom of enquiry, state and corporate interests in the Big Data age raises important questions about power and control in the academy, which in turn have implications for the norms of research governance.
Longitudinal associations of experiential and reflective dimensions of meaning in life with psychopathological symptoms
Authors: Anoschin Albert , Zürn Michael K. , Remmers Carina 
Published: September 2024

Background
Rather than being rooted in deliberate reflection, the experience of meaning has been shown to evolve from intuitive processes (Heintzelman & King, 2013b, https://doi.org/10.1007/978-94-007-6527-6_7). Accordingly, experiential and reflective dimensions of meaning in life can be distinguished (Hill et al., 2019, https://doi.org/10.1080/09515070.2018.1434483). In this preregistered study, we explored how these dimensions are longitudinally associated with psychopathological symptoms. We expected that experiencing more meaning would predict fewer depressive symptoms and fewer personality functioning impairments six months later, whereas reflecting about meaning would predict more psychopathological symptoms.

Method
A German-speaking sample of N = 388 completed self-report measures assessing meaning in life, depression, and personality functioning at baseline and six months later.

Results
Controlling for depression at baseline, elevated levels of experiencing meaning in life predicted a decrease in depressive symptoms. Experiencing meaning did not predict personality functioning impairments six months later. However, exploratory analyses with a larger sample tentatively showed that experiencing meaning in life predicted less impairments in personality functioning. Evidence supporting the hypothesized association between reflection and future depression as well as future personality functioning impairments was discerned through exploratory analyses. Generalizability of results to clinical care settings is limited due to the studied non-clinical sample. No causal conclusions can be drawn from the data because the study employed an observational design with two assessment points.

Conclusion
Experiencing meaning in life emerged as a potential protective factor against future psychopathological symptoms, whereas exploratory analyses pointed to an opposite relationship for reflection about meaning in life. Results are discussed with regard to clinical implications and directions for future research.
Políticas públicas de segurança alimentar e nutricional no empoderamento de mulheres agricultoras
Authors: Cerqueira Soares Martins Souto Marília , Gomes Barreto Cristiane , De Carvalho Canavesi Flaviane 
Published: September 2024

A pesquisa verificou de que forma a implementação de ações de promoção da Segurança Alimentar e Nutricional, executadas no Distrito Federal, influenciaram o empoderamento de agricultoras em dois pré-assentamentos rurais, a saber: Chapadinha e Pequeno William. Foram realizadas entrevistas e o levantamento de documentos em órgãos responsáveis por operacionalizar as políticas públicas. Observou-se o impacto das ações e das políticas analisadas sobre o empoderamento das entrevistadas. A pesquisa mostrou a dificuldade de acesso à terra em ambas as comunidades estudadas, sendo que o assentamento Chapadinha ainda está no processo de oficialização, logo, tem restrições para realizar investimentos de infraestrutura produtiva e social. Também foi observada a existência da insegurança hídrica, especialmente no Pequeno William, o que limita a produção de alimentos pelas agricultoras e as impede de acessar programas de compras institucionais. A interação entre água, energia e alimento ficou evidenciada no caso estudado, visto que o sucesso das políticas de Segurança Alimentar e Nutricional depende igualmente das seguranças hídrica e energética, conforme abordagem Nexus.
Editorial: Os 20 anos da Associação Brasileira de Agroecologia
Authors: Martins Sérgio Roberto 
Published: September 2024

Celebremos os 20 anos da ABA-Agroecologia como semente plantada em solo fértil resultando em árvore frondosa, cuja copa imensamente ramificada emerge de um tronco robusto assentado e alimentado por raízes sadias.
Há que se destacar o fértil período político que enseja a fundação da ABA-Agroecologia (2004) e da criação da Revista Brasileira de Agroecologia (2006), na esteira de importantes eventos tais como o II Congresso Brasileiro de Agroecologia, V Seminário Internacional sobre Agroecologia e VI Seminário Estadual sobre Agroecologia. Esta série de eventos evidenciam contextos em que os princípios da Agroecologia foram emergindo e constituindo-se num processo epistêmico para o qual as políticas públicas foram sendo convocadas a abrir caminhos, tanto no âmbito da academia, da pesquisa, da extensão, dos movimentos sociais, agricultores familiares, consumidores, etc. Um contexto construído num movimento “de baixo para cima”, um contexto de mobilização social. O mais importante como desafio futuro da ABA-Agroecologia está em abrir espaço para o fundamental debate sobre a episteme agroecológica, promovendo a ideia de que não se tem um modelo pronto e acabado da Agroecologia.
Analisis Penguasaan Konsep Dan Kemampuan Berargumentasi Siswa Dengan Model Argument Driven Inquiry Berbasis Socio-Scientific Issue
Authors: Pelegia Dianti  , Ari Sunandar  , Anandita Eka Setiadi  
Published: September 2024

Model pembelajaran yang digunakan di SMA Taman Mulia Kubu Raya masih kurang sesuai dengan materi yang diajarkan dan guru menggalami kendala dalam mengaitkan isu-isu atau fenomena sains dalam pembelajaran. Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Argument Driven Inquiry berbasis Socio-Scientific Issue terhadap penguasaan konsep dan kemampuan berargumentasi siswa kelas XI SMA Taman Mulia. Penelitian ini dilaksanakan pada semester genap tahun ajaran 2022/2023. Penelitian ini menggunakan Quasy Eksperimental dengan rancangan Nonequivalent Control Group Design. Pengumpulan data menggunakan test pilihan ganda dan uraian. Analisis data menggunakan interprestasi effect size dengan interprestasi Cohen. Hasil penelitian menunjukan bahwa pembelajaran dengan model Argument Driven Inquiry berbasis Socio-Scientific Issue berpengaruh pada penguasaan konsep siswa sebesar 65,3% dengan nilai effect size sebesar 1.37 dan berpengaruh terhadap kemampuan berargumentasi sebesar 58,9% dengan nilai effect size sebesar 1.12. Kesimpulan model pembelajaran Argument Driven Inquiry berbasis Socio-Scientific Issue berpengaruh besar terhadap penguasaan konsep dan kemampuan berargumentasi siswa.
Efektivitas Media Articulate Storyline Terhadap Minat dan Retensi Siswa Pada Materi Biologi SMA Taman Mulia
Authors: Mauri Adisti  , Mahwar Qurbaniah  , Hanum Mukti Rahayu  
Published: September 2024

Pemilihan penggunaan media pembelajaran diperlukan untuk menciptakan kondisi pembelajaran yang efektif dan inovatif yang mendukung proses pembelajaran, salah satunya media articulate storyline. Penelitian ini bertujuan untuk mengetahui efektivitas media articulate storyline terhadap minat dan retensi siswa. Metode penelitian yang digunakan yaitu Quasi Experimental Design dengan rancangan Nonequivalent Control Group Design. Perlakuan di kelas eksperimen (XI IIS 2) menggunakan media articulate storyline dan di kelas kontrol (XI IIS 1) menggunakan PPT. Teknik pengumpulan data menggunakan teknik pengukuran soal dan angket. Alat pengumpul data yang digunakan adalah tes dan lembar angket. Hasil penelitian menunjukkan penggunaan media articulate storyline efektif terhadap minat dan retensi siswa. Minat siswa kelas eksperimen berbeda secara signifikan dengan kelas kontrol (nilai independent samples t-test 0,000) dan dipengaruhi perlakuan sebesar 55,4%(nilai Effect Size 1,00). Retensi siswa kelas eksperimen berbeda secara signifikan dengan kelas kontrol (nilai U-Mann Whitney 0,006) dan dipengaruhi perlakuan sebesar 51,6% (nilai Effect Size 0,92).
Monte Carlo simulation and PMF model for assessing human health risks associated with heavy metals in groundwater: a case study of the Nubian aquifer, Siwa depression, Egypt
Authors: Eid Mohamed Hamdy , Mikita Viktoria , Eissa Mustafa , Ramadan Hatem Saad , Mohamed Essam A. , Abukhadra Mostafa R. , El-Sherbeeny Ahmed M. , Bellucci Stefano , Kovács Attila , Szűcs Péter 
Published: September 2024

IntroductionThe groundwater in arid countries such as Egypt represent the main water resources in the desert regions due to the long distance between these regions (oasis) and Nile River. Contamination of these limited water resources with toxic metals threaten the health of individuals in these regions.MethodsThe current study integrates isotopic tracers, hydrogeochemistry, geophysical logs, positive matrix factorization (PMF model), and Monte Carlo (MCS) simulation for pollution source apportionment and health risks associated with heavy metals in the Nubian Sandstone aquifer (NSSA).Results and DiscussionThe water resource used for drinking purposes (NSSA) is pale meteoric water (non-rechargeable aquifer). Silicate weathering, old trapped sea water, reverse ion exchange evaporation, and dissolution are the dominant mechanisms controlling water chemistry. PMF model showed that the major ions and heavy metals in groundwater of the NSSA originated from four significant sources (anthropogenic activities, dissolution of minerals, iron-bearing minerals, mixing with old trapped seawater, and hydrothermal water). The total risk (HI) oral values highlighted significant non-carcinogenic dangers for adults and children through the oral exposure. At the same time, dermal contact posed a no risk for adults and a high risk for children. Most samples had carcinogenic risk (CR) values higher than the allowed limits (1.0E-4) for metals like Cadmium, chromium, and lead, suggesting carcinogenic effects across all age groups. The Monte Carlo approach-based health concern evaluation model assessed the 5th % CR oral values (child) as 0.00012, 0.0036, and 0.0088 for Cd, Cr, and Pb, respectively, indicating more significant potential dangers to children. Urgent and comprehensive water treatment measures are imperative to mitigate the identified carcinogenic and non-carcinogenic health risks in the study area.
An education model to empower women in tech entrepreneurship
Authors: Paiva Teresa , Felgueira Teresa , Alves Catarina , Gomes Natalia , Salgado Sofia , Salaberri Marcelo 
Published: September 2024

IntroductionThe gender gap in technology entrepreneurship represents a significant and persistent disparity, with women significantly underrepresented in creating and leading technology start-ups. To address this multifaceted problem, it is critical to research and implement educational models that can foster intrinsic motivation in aspiring female entrepreneurs. Self-Determination Theory (SDT) provides a valuable framework for such an educational approach, emphasizing the importance of satisfying essential psychological needs—autonomy, competence and relatedness—to enhance motivation and commitment. Integrating SDT principles into entrepreneurship education can create supportive environments that empower women, encourage diverse perspectives, and ultimately bridge the gender gap in tech entrepreneurship. Particularly in the case of female students, it is important to understand how to empower their behavior choices to make possible different professional paths, with tech entrepreneurship being one of them. This gender gap has not yet been addressed through an education model proposal. Much has been said to characterize and identify it, but there is no proposal to change the higher education system in the STEM area, which is the research goal achieved in this paper: we need to analyze the gender gap in HEI and its relation to becoming entrepreneurial and understand how HEI may support the tech entrepreneurial behavior. To answer these questions we are going, in pursuit of the intrinsic motivations to support more entrepreneurial behavior in STEM female students.MethodsA quantitative approach was designed to collect data to identify the gender gap in five European higher education institutions (HEI) in five different countries. In April, surveys were launched to female students, allowing a descriptive, exploratory factor analysis and structural equation modeling to test the SDT intrinsic motivation constructs.ResultsThe results confirmed that there is a gender gap to overcome and that the teaching-learning process may help to potentiate the female student’s capacities of self-knowledge and self-value for female students. The autonomy need was identified as the most influential construct on students becoming entrepreneurs, not dishing the effect the competences and relatedness have. Understanding this reality allows for further development of the education model proposed and discussed.ConclusionHigher education lectures, particularly in STEM programs, can improve their teaching processes to become more inclusive and promote an effective entrepreneurial mindset. Understanding what will change helps engage in a different paradigm of education in technology, demystifying the concepts of entrepreneurship and allowing inclusion and gender equality in the higher education system.
Clinical performance of a novel and rapid bioassay for detection of thyroid-stimulating immunoglobulins in Graves’ orbitopathy patients: a comparison with two commonly used immunoassays
Authors: Hötte Gijsbert J. , de Bie Maaike , de Keizer Ronald O.B. , Kolijn P. Martijn , Drexhage Roosmarijn C. , Veenbergen Sharon , Versnel Marjan A. , van Hagen P. Martin , Paridaens Dion , Dik Willem A. 
Published: September 2024

BackgroundFor the selective detection of thyroid-stimulating hormone receptor antibodies with stimulating properties (thyroid-stimulating immunoglobulins; TSI), a novel and rapid bioassay (Turbo TSI) has been introduced. We evaluate the clinical performance of Turbo TSI in Graves’ orbitopathy (GO) patients and compare it to a bridge-based TSI binding immunoassay and third generation TSH-R-binding inhibitory immunoglobulins (TBII) assay. Also, we investigate the association of Turbo TSI and TBII measurements with GO activity and severity, as well as response to intravenous methylprednisolone (IVMP), and compare results to previous findings on the bridge-based TSI binding immunoassay.MethodsTurbo TSI, TBII and bridge-based TSI binding immunoassay measurements were performed in biobank serum from 111 GO patients and control cases (healthy controls [HC; n=47], primary Sjögren’s disease [SD; n=10], systemic sclerosis [SSc; n= 10], systemic lupus erythematosus [SLE; n=10]). Clinical characteristics and response to treatment were retrospectively retrieved from GO patient files.ResultsTurbo TSI had the highest sensitivity (97.3%) and negative predictive value (96.1%), while bridge-based TSI binding immunoassay showed the highest specificity (100%) and positive predictive value (100%). Differentiating GO patients from control cases, receiver operating characteristic (ROC) analysis showed an area under the curve (AUC) of 98.5%, 95.7% and 99.8% for Turbo TSI, TBII and bridge-based TSI binding immunoassay, respectively. Turbo TSI (p&lt;0.001) and TBII (p&lt;0.01) levels were higher in patients with active compared to inactive GO. Correlation with CAS was stronger for Turbo TSI (r=0.42) than TBII (r=0.25). No statistically significant differences were observed in IVMP responders vs. non-responders for Turbo TSI (p=0.092) and TBII (p=0.21). For identifying active GO, an AUC of 75% with Turbo TSI and 67% with TBII was found. For IVMP response, AUC was 66.3% with Turbo TSI and 62.1% with TBII. In multivariate logistic regression analyses, both assays were independently associated with disease activity (p&lt;0.01 for both assays) and IVMP response (p&lt;0.01 for Turbo TSI; p&lt;0.05 for TBII).ConclusionsThe new Turbo TSI functional bioassay has good clinical performance. Although turbo TSI is a stronger marker of activity and IVMP response than TBII, results are comparable to our previously published findings on the bridge-based TSI binding immunoassay.
Pregnane X receptor reduces particulate matter-induced type 17 inflammation in atopic dermatitis
Authors: Lee Ji Su , Lee Youngae , Jang Sunhyae , Oh Jang-Hee , Lee Dong Hun , Cho Soyun 
Published: September 2024

BackgroundEpidemiological evidence suggests that particulate matter (PM) exposure can trigger or worsen atopic dermatitis (AD); however, the underlying mechanisms remain unclear. Recently, pregnane X receptor (PXR), a xenobiotic receptor, was reported to be related to skin inflammation in AD.ObjectivesThis study aimed to explore the effects of PM on AD and investigate the role of PXR in PM-exposed AD.MethodsIn vivo and in vitro AD-like models were employed, using BALB/c mice, immortalized human keratinocytes (HaCaT), and mouse CD4+ T cells.ResultsTopical application of PM significantly increased dermatitis score and skin thickness in AD-like mice. PM treatment increased the mRNA and protein levels of type 17 inflammatory mediators, including interleukin (IL)-17A, IL-23A, IL-1β, and IL-6, in AD-like mice and human keratinocytes. PM also activated PXR signaling, and PXR knockdown exacerbated PM-induced type 17 inflammation in human keratinocytes and mouse CD4+ T cells. In contrast, PXR activation by rifampicin (a human PXR agonist) reduced PM-induced type 17 inflammation. Mechanistically, PXR activation led to a pronounced inhibition of the nuclear factor kappa B (NF-κB) pathway.ConclusionIn summary, PM exposure induces type 17 inflammation and PXR activation in AD. PXR activation reduces PM-induced type 17 inflammation by suppressing the NF-κB signaling pathway. Thus, PXR represents a promising therapeutic target for controlling the PM-induced AD aggravation.
Exploring the gut microbiota of healthy captive Asian elephants from various locations in Yunnan, China
Authors: Wang Yuhan , Wang Yixuan , Zhou Jiuxuan , Bao Mingwei , Shah Taif , Yang Song , Zheng Jing , Li Qian , Hou Yutong , Wang Binghui , Yuan Ruiling 
Published: September 2024

IntroductionThe Asian elephant (Elephas maximus) is a giant herbivore classified as an endangered wildlife species by the International Union for Conservation of Threatened Species.This study aims to investigate and compare the core gut microbiota of captive Asian elephants from three different locations in Yunnan Province, China, to explore the impact of environmental and husbandry factors on microbial diversity.MethodsWe collected fecal samples from 29 captive Asian elephants from three locations and performed full-length 16S rRNA gene sequencing. Microbial diversity was assessed using alpha diversity (Chao1 and Shannon indexes) and beta diversity (Bray-Curtis and Euclidean distance metrics). Principal coordinate analysis (PCoA) was used to visualize microbial variation among groups.ResultsAlpha diversity analysis showed that the microbial diversity in the Yexianggu group was higher than that in the other groups. Bray-Curtis and Euclidean metrics revealed significant differences among the microbial communities. Bacteroidetes and Firmicutes, which are key cellulose-degrading bacteria, were the dominant phyla in all groups. Synergistaceae was the most abundant family in the Menghai group, while Lachnospiraceae and Pirellulaceae were more abundant in the Yexianggu and Yuantongshan groups, respectively. Genus p-1008-a5-gut-group was more abundant in Yexianggu, and Prevotella was predominant in Menghai.DiscussionThese results indicate that habitat and husbandry practices significantly influence the gut microbiota of captive Asian elephants. The identification of bacterial species such as Lactobacillus fermentum, Clostridium neonatale, Enterococcus mundtii, Klebsiella huaxiensis, Corynebacterium nasicanis, and Streptococcus equinus highlights the potential role of specific microbes in maintaining host-microbial interactions. Promoting microbial diversity through improved captive conditions could enhance the health of these endangered animals.
Trust of inpatient physicians among parents of children with medical complexity: a qualitative study
Authors: Dewan Tammie , Whiteley Andrea , MacKay Lyndsay Jerusha , Martens Rachel , Noel Melanie , Barnard Chantelle , Jordan Isabel , Janvier Anne , Thorne Sally 
Published: September 2024

BackgroundTrust is a foundation of the therapeutic relationship and is associated with important patient outcomes. Building trust between parents of children with medical complexity (CMC) and physicians during inpatient care is complicated by lack of relational continuity, cumulative (sometimes negative) parent experiences and the need to adjust roles and expectations to accommodate parental expertise. This study's objective was to describe how parents of CMC conceptualize trust with physicians within the pediatric inpatient setting and to provide recommendations for building trust in these relationships.MethodsInterviews with 16 parents of CMC were completed and analyzed using interpretive description methodology.ResultsThe research team identified one overarching meta theme regarding factors that influence trust development: situational awareness is needed to inform personalized care of children and families. There were also six major themes: (1) ensuring that the focus is on the child and family, (2) respecting both parent and physician expertise, (3) collaborating effectively, (4) maintaining a flow of communication, (5) acknowledging the impact of personal attributes, and (6) recognizing issues related to the healthcare system.DiscussionMany elements that facilitated trust development were also components of patient- and family-centered care. Parents in this study approached trust with inpatient physicians as something that needs to be earned and reciprocated. To gain the trust of parents of CMC, inpatient physicians should personalize medical care to address the needs of each child and should explore the perceptions, expertise, and previous experiences of their parents.