bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abstract A066: Unmasking differences in adolescent HPV vaccine uptake in six Asian American subgroups: data from the national immunization survey-teen (2015-2019)
Authors: Zhu Lin , Liu Elaine Z. , Siu Philip , Pan Chun , Ma Grace X. 
Published: September 2024

Abstract
Introduction: The HPV vaccination rates among Asian American adolescents were found to be below optimal levels. Understanding the high-risk demographics and the various factors influencing HPV vaccine acceptance is essential for addressing disparities and enhancing vaccination rates in this population. This study aimed to investigate HPV vaccine uptake in adolescents aged 13 to 17 across six major Asian American ethnic groups using nationally representative data. Methods: The study analyzed data from the National Immunization Survey- Teen (2015-2019), comprising 3,968 Asian American adolescents from Asian Indian, Chinese, Filipino, Japanese, Korean, and Vietnamese backgrounds. Provider and practice characteristics were examined alongside HPV vaccine initiation and completion rates within each subgroup. Results: Findings revealed that while the overall initiation rate among Asian American adolescents was 66.65%, significant variations existed among subgroups, ranging from 57.3% in Asian Indians to 71.22% in Chinese adolescents. Similarly, completion rates ranged from 30.89% in Asian Indians to 48.14% in Chinese adolescents, with an aggregated completion rate of 40.37% for the total Asian American sample. Household survey data generally showed lower initiation and completion rates compared to provider-reported data but still reflected subgroup disparities. Conclusion: Across all ethnic groups, a common barrier to HPV vaccination was the lack of physician recommendation. However, slight variations in this barrier were observed among subgroups. These findings underscore the importance of considering socioeconomic, cultural, and acculturation-related factors in designing effective public health and clinical interventions to promote HPV vaccination among Asian American adolescents.
Citation Format: Lin Zhu, Elaine Z. Liu, Philip Siu, Chun Pan, Grace X. Ma. Unmasking differences in adolescent HPV vaccine uptake in six Asian American subgroups: data from the national immunization survey-teen (2015-2019) [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A066.
Abstract A078: Cancer Incidence in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) – The Onco-SOL Ancillary Study
Authors: Parada Humberto , Agalliu Ilir , Sotres-Alvarez Daniela , Olshan Andrew F. , Evenson Kelly R. , Rohan Thomas E. , Kaplan Robert C. , Thompson Caroline A. , Gallo Linda C. , Penedo Frank J. , Cai Jianwen , Wassertheil-Smoller Sylvia , Thyagarajan Bharat , Thomas Stefani N. , Garcia-Bedoya Olga L. , Talavera Gregory A. 
Published: September 2024

Abstract
This abstract is being presented as a short talk in the scientific program. A full abstract is printed in the Proffered Abstracts section (PR015) of the Conference Program/Proceedings.
Citation Format: Humberto Parada, Ilir Agalliu, Daniela Sotres-Alvarez, Andrew F. Olshan, Kelly R. Evenson, Thomas E. Rohan, Robert C. Kaplan, Caroline A. Thompson, Linda C. Gallo, Frank J. Penedo, Jianwen Cai, Sylvia Wassertheil-Smoller, Bharat Thyagarajan, Stefani N. Thomas, Olga L. Garcia-Bedoya, Gregory A. Talavera. Cancer Incidence in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) – The Onco-SOL Ancillary Study [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A078.
Abstract A083 Ethnic disparities in esophageal cancer across New York State
Authors: Park Inae , Park Sungjae , Lee Misuk 
Published: September 2024

Abstract
Introduction Esophageal cancer is one of the most fatal cancers in the United States. Moreover, disparities in mortality, or incidence rates of esophageal cancer have been reported. Here, we conducted a retrospective study to investigate disparities in esophageal cancer in the state of New York. Method Mortality and 5-year survival rate were analyzed through Surveillance, Epidemiology, and End Results (SEER) Stat Database (1969-2022). Mortality and survival data were analyzed by counties in the state of New York. The 5-year survival was analyzed through the Kaplan-Meier curve and SEER combined staging and ethnicity (non-hispanic white; NHW, non-hispanic black; NHB, Asians/Pacific Islanders; API, and Hispanics). Result Bronx County revealed the highest mortality rate among New York City Counties (5.6 per 100,000, 95% CI, 5.4-5.8), and Queens County showed the lowest mortality. (3.9 per 100,000, 95% CI, 3.7-4.0). In localized esophageal cancer, one year survival was highest in the NHW (79.3%, 95% CI, 75.9- 82.2%) in New York, whereas 2-5 year survival rates were highest in the NHB (52.0%, 47.3%, 40.2%, and 38.4%, respectively). Hispanics showed the lowest survival rate in the localized stage. In comparison, API showed the highest survival (1-5 year survival 46.8%, 29.6%, 16.8%, 13.3%, and 12.1% respectively) and NHB revealed the lowest survival outcome in distant metastatic esophageal cancer (1-5 year survival 28.8%, 13.5%, 8.1%, 5.9%, and 5.1% respectively) throughout 5 years. Conclusion Mortality and 5 year survival rates varied across the boroughs of New York City. Early intervention and primary prevention could be especially beneficial in the Bronx, where targeted efforts could help prevent patients from advancing to the distant metastatic stage, considering the unique demographics and healthcare disparities in this area.
Citation Format: Inae Park, Sungjae Park, Misuk Lee. Ethnic disparities in esophageal cancer across New York State [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A083.
Abstract A089: Intersecting burdens: The role of social barriers and perceived stress in moderating cortisol reactivity among African American breast cancer survivors
Authors: Sanogo Dr. Fatimata , Cho Dr. Junhan , Beard Dr. Trista , Chanita Hughes Halbert Dr. 
Published: September 2024

Abstract
Background: Disparities in breast cancer morbidity and mortality persist in African Americans. Social determinants and their subsequent effect on stress reactivity may impact the biological mechanisms associated with the onset and progression of cancer. However, stress reactivity has not been examined specifically among African American breast cancer survivors. Objective: To evaluate within-subject variation in stress reactivity among African American breast cancer survivors and determine whether this reactivity is influenced by social stressors, such as financial strain and social isolation, known to be associated with cancer outcomes. Methods: We conducted a laboratory intervention study using the Trier Social Stress Test on African American breast cancer survivors. We measured stress reactivity using salivary cortisol levels; socioeconomic, social, and psychological stressors were estimated by self-report. We performed multi-level random effect repeated-measures linear regression models to estimate within-subject changes in cortisol levels. We tested the moderating effects of social factors and cumulative social stressors on reactivity outcomes. Results: Sixty African American breast cancer survivors were included in the study. There were significant increases in mean cortisol levels at 30 minutes (beta=0.054, 95%CI=0.026, 0.082; p&lt;0.001) and 40 minutes (beta=0.040, 95% CI=0.015, 0.065; p=.002) post-stress during the recovery period. We identified significant interactions between time and social stressors on cortisol levels for financial strain (χ2/df=15.83/4, p=.003), social isolation (χ2/df=9.67/4, p=.04), negative life events (χ2/df=12.75/4, p=.01), perceived stress (χ2/df=11.93/4, p=.02), and cumulative index of social stressors (χ2/df=11.14/4, p=.03). Conclusion: Social risk factors moderate the effects of stressors on cortisol reactivity among African American breast cancer survivors. There is a need to understand the lived experiences of Black women and develop interventions that mitigate the impact of social stressors on stress responses.
Citation Format: Dr. Fatimata Sanogo, Dr. Junhan Cho, Dr. Trista Beard, Dr. Chanita Hughes Halbert. Intersecting burdens: The role of social barriers and perceived stress in moderating cortisol reactivity among African American breast cancer survivors [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A089.
Abstract A094: Association between head and neck squamous cell carcinoma survival, tobacco use, and alcohol use, 2010-2021
Authors: Rahman Rashad , Chen Meng , Osazuwa-Peters Nosayaba 
Published: September 2024

Abstract
The number of survivors of head and neck squamous cell carcinoma (HNSCC) in the United States is expected to rise in coming years due to higher quality and more accessible cancer care, diminished smoking and alcohol consumption rates, and increased frequency of less aggressive human papillomavirus (HPV)-associated oropharyngeal cancers. In developed nations, about 80% of HNSCC patients are current smokers, recent quitters (within the past year), and former smokers. About 39% of HNSCC patients living in the United States say that they are current drinkers, drinkers who exceed moderate levels, and binge drinkers. Of all HNSCC cases, between 72% and 80% are associated with specifically tobacco use, alcohol use, or the two. Tobacco use and alcohol consumption have been shown to be predictive for HNSCC diagnosis and survival. However, the underlying trends and social determinants linking HNSCC survival to tobacco use and alcohol consumption are poorly understood. To reach a better understanding, data will be sourced from the National Health Interview Survey from 2010 to 2021, adjusted for age and other confounders, and then analyzed with Cox proportional hazards regression analysis. The results will inform a deeper understanding of the connections between HNSCC survival and tobacco and alcohol use and can point to new approaches and treatment targets for patient care.
Citation Format: Rashad Rahman, Meng Chen, Nosayaba Osazuwa-Peters. Association between head and neck squamous cell carcinoma survival, tobacco use, and alcohol use, 2010-2021 [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A094.
Abstract A123: Awareness of human papillomavirus (HPV) and its vaccine and telehealth: Results from the Health Information National Trends Survey (HINTS) 6, 2022 in the United States
Authors: Desai Manali , Igab Iman , Ezeigwe Ogochukwu , Malgave Devesh 
Published: September 2024

Abstract
Background: Human Papillomavirus (HPV) vaccination is essential to prevent occurrences of a variety of HPV associated cancers. The awareness of HPV and its vaccine could be associated with the use of telehealth. The aims of this study were to examine the association between awareness of HPV and HPV vaccine with receiving telehealth for health care within the past year. Methods: Data from the Health Information National Trends Survey (HINTS) 6 (N=5,887) were utilized. Dependent variable was awareness of HPV and HPV vaccine. The independent variable was those who received care from a doctor or health professional using telehealth. Weighted multivariable logistic regression was performed to determine association of awareness of HPV and its vaccine with receiving healthcare using telehealth while adjusting for age, gender, race, education, and census region. Results: The study sample consisted of 68.28% awareness of HPV and 63.47% awareness of HPV vaccine. After controlling for covariates, we found those who were aware of HPV and HPV vaccine have received telehealth care (aOR=1.40, 95%CI:1.11-1.78; aOR= 1.40, 95%CI:1.09 -1.80), respectively. In the adjusted model, the awareness of HPV for being female (aOR=2, 95%CI:1.60-2.48) and college graduates (aOR=3.80, 95%CI: 2.59-6.56). In the adjusted model, the awareness of HPV vaccine for being female (aOR= 2.68, 95%CI:2.13-3.36) and college graduates (aOR=4.68,95%CI:2.77-7.91). HPV and HPV vaccine awareness, Non Hispanic Whites had significantly higher adjusted odds compared to other race/ethnicity groups. Conclusion: Hence public health programs could be directed to promote use of telehealth to increase awareness of HPV causing cancers, reduce stigma associated with vaccination, boost healthcare recommendation and uptake of HPV vaccination considering socio demographic factors.
Citation Format: Manali Desai, Iman Igab, Ogochukwu Ezeigwe, Devesh Malgave. Awareness of human papillomavirus (HPV) and its vaccine and telehealth: Results from the Health Information National Trends Survey (HINTS) 6, 2022 in the United States [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A123.
Abstract A124: An examination of trust in biomedical research among the Witness Project’s community health workers
Authors: Devonish Julia , Mahoney Martin , Bouchard Elizabeth , Dauphin Cassy , Ali Abshiro , Meadows Veronica , Colon Jomary , Johnson Dee 
Published: September 2024

Abstract
The Witness Project® (NWP) was established in 1991 and has maintained its status as one of NCI’s Evidence Based Cancer Control Program (EBCCP) for decades. NWP is a self-sustaining, culturally competent, grass roots level community-based intervention program that uses breast and cervical cancer survivors known as Witness Role Models and Community Health Workers (CHW). With many locations in unserved communities throughout the United States, NWP provides relevant cancer related education and navigates minority residents through successful completions of cancer related screenings. Health disparities are a longstanding problem due in part to underrepresentations of historically underserved populations in research. Increasing minority and underserved individuals’ participation in research has great disparity mitigating potential. A team of newly trained Black and Hispanic NWP CHW (n=25) will be created as part of a larger multiphase preliminary pilot study designed to increase diverse individuals’ participations in research within Roswell Park’s catchment area. Design, Measures, Setting, and Participants. The primary objective of this cross-sectional study is to assess Black and Hispanic CHW’s trust in biomedical research. Secondary objectives are to explore the feasibility and acceptability of 1) NWP CHW training, and 2) an informal educational intervention about the importance of minority representations in research and it potential to mitigate health disparities. CMWs will complete the Perceptions of Research Trustworthiness (PoRT) scale to evaluate their trust and distrust in biomedical research before and after viewing the informal educational intervention. Preliminary Results and Planned Analyses At the time of abstract submission nineteen CMWs have completed their NWP and CITI training and PoRT assessments. Fifteen CHWs were Black (78.9%) and four Hispanic (21.1%). When all 25 CMWs are trained we will calculate overall and individual item Trust and Distrust subscale scores. Regarding feasibility and acceptability of the CHW training and the informal education intervention, semi structured interviews will provide qualitative feedback and independent samples t-test will be used to compare pre-and post-informal education intervention PoRT scores.
Citation Format: Julia Devonish, Martin Mahoney, Elizabeth Bouchard, Cassy Dauphin, Abshiro Ali, Veronica Meadows, Jomary Colon, Dee Johnson. An examination of trust in biomedical research among the Witness Project’s community health workers [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A124.
Abstract A142: A qualitative assessment of the acceptability of Human Papillomavirus (HPV) self-sampling and informational materials among diverse populations
Authors: Petrik Amanda , Rivelli Jennifer , Firemark Allison , Johnson Cheryl , Locher Blake , Gille Sara , Schneider Jennifer 
Published: September 2024

Abstract
Background: Disparities in cervical cancer screening rates among marginalized groups is a driver of inequalities in cervical cancer. Self-sampling for human papillomavirus (HPV) testing is a newly emerging alternative to clinician-performed testing to screen for cervical cancer, and has high potential to reduce screening barriers in under-screened and marginalized groups. We study the acceptability in of HPV self-sampling and informational materials among Black/African American, Hispanic/Spanish speaking, American Indian/Alaska Native and transgender/nonbinary populations. Methods: We conducted qualitative interviews with patients, ages 30-65, who were female at birth, Black/African American, Hispanic, American Indian, and/or transgender/nonbinary. Telephone interviews were conducted in English or Spanish. Patients did not complete the test, rather were asked about the attractiveness, comprehensibility, and acceptability of the HPV self-test, instructions, and messaging. Results: Among 23 completed interviews (5 American Indian/Alaska Native, 7 Hispanic (2 bilingual, 5 Spanish-speaking), 5 Black/African American, and 6 transgender/nonbinary), patients from all groups thought the test was straightforward and convenient, and they would complete the test at home or in clinic. The transgender/nonbinary patients preferred at home testing. American Indian and transgender/nonbinary patients liked that the test might avoid pain, discomfort, and invasiveness. All patients liked the letter and instructions. All groups had specific suggestions for making the materials more culturally acceptable. Conclusions: The HPV self-test and the instructions and materials for use were acceptable for a diverse group of patients. Tailored outreach and messaging should be considered to reduce screening disparities among groups that have been historically underserved by the medical system.
Citation Format: Amanda Petrik, Jennifer Rivelli, Allison Firemark, Cheryl Johnson, Blake Locher, Sara Gille, Jennifer Schneider. A qualitative assessment of the acceptability of Human Papillomavirus (HPV) self-sampling and informational materials among diverse populations [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A142.
Abstract A143: The development of a risk prediction model to predict patients’ likelihood of completing human papillomavirus vaccination
Authors: Petrik Amanda A. , Slaugher Matthew , Coronado Gloria , Johnson Eric 
Published: September 2024

Abstract
Background: Human Papillomavirus (HPV) cancers can be preventable if HPV vaccination is received in adolescents before the age of 13, yet only 55% of Oregonian adolescents had an HPV series completion in 2020.2 The recommended vaccination age for HPV recently dropped to age 9. This new recommended age allows providers to offer HPV vaccination with routine vaccinations. To further increase HPV vaccination rates, research is critically needed on new interventions to promote vaccination among vaccine resistant groups, and populations that are most in need of targeted interventions. We assessed patterns in vaccination from 2015-2022, in preparation of the development of a prognostic risk prediction model to identify patients’ likelihood of obtaining HPV vaccination. Methods: We used a retrospective cohort from a large health system to assess vaccination patterns from 2015-2022. Eligible patients were members of Kaiser Permanente Northwest, 9-18 years old, and did not have a history of adverse vaccination outcomes. We assessed vaccination initiation, completion by age, gender and year. Results: Among 29,398 eligible patients, 44.3% had no vaccination, 14.5% had one dose, and 41.2% had completed the series. More patients were vaccinating at earlier ages from 2015-2022. Of those with one dose or who had completed the series, 84% had vaccinated by the age of 12 in 2022 compared to 74% in 2015. The change was greater in boys with 70.5% before age 12 in 2015 compared with 84% in 2022. ConclusionsWhile efforts to increase HPV vaccination and initiate at younger ages have been successful, efforts need to be targeted to specific populations. The patterns of HPV vaccination over the past 7 years highlights improvement, but system level interventions may be needed to adequately increase vaccination among resistant populations. This presentation will discuss the assessment of vaccination patterns in preparation of the development of a prognostic risk prediction model and describe how the model will be used in a system to target populations for early interventions to complete vaccination.
Citation Format: Amanda A. Petrik, Matthew Slaugher, Gloria Coronado, Eric Johnson. The development of a risk prediction model to predict patients’ likelihood of completing human papillomavirus vaccination [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A143.