bluuebunny/crossref_metadata_2025_split huggingface dataset:
A refined ecological risk assessment for California red-legged frog, Delta smelt, and California tiger salamander exposed to malathion
Authors: Clemow Yvonne H , Manning Gillian E , Breton Roger L , Winchell Michael F , Padilla Lauren , Rodney Sara I , Hanzas John P , Estes Tammara L , Budreski Katherine , Toth Brent N , Hill Katie L , Priest Colleen D , Teed R Scott , Knopper Loren D , Moore Dwayne RJ , Stone Christopher T , Whatling Paul 
Published: October 2017

Abstract

The California red-legged frog (CRLF), Delta smelt (DS), and California tiger salamander (CTS) are 3 species listed under the United States Federal Endangered Species Act (ESA), all of which inhabit aquatic ecosystems in California. The US Environmental Protection Agency (USEPA) has conducted deterministic screening-level risk assessments for these species potentially exposed to malathion, an organophosphorus insecticide and acaricide. Results from our screening-level analyses identified potential risk of direct effects to DS as well as indirect effects to all 3 species via reduction in prey. Accordingly, for those species and scenarios in which risk was identified at the screening level, we conducted a refined probabilistic risk assessment for CRLF, DS, and CTS. The refined ecological risk assessment (ERA) was conducted using best available data and approaches, as recommended by the 2013 National Research Council (NRC) report “Assessing Risks to Endangered and Threatened Species from Pesticides.” Refined aquatic exposure models including the Pesticide Root Zone Model (PRZM), the Vegetative Filter Strip Modeling System (VFSMOD), the Variable Volume Water Model (VVWM), the Exposure Analysis Modeling System (EXAMS), and the Soil and Water Assessment Tool (SWAT) were used to generate estimated exposure concentrations (EECs) for malathion based on worst-case scenarios in California. Refined effects analyses involved developing concentration–response curves for fish and species sensitivity distributions (SSDs) for fish and aquatic invertebrates. Quantitative risk curves, field and mesocosm studies, surface-water monitoring data, and incident reports were considered in a weight-of-evidence approach. Currently, labeled uses of malathion are not expected to result in direct effects to CRLF, DS or CTS, or indirect effects due to effects on fish and invertebrate prey. Integr Environ Assess Manag 2018;14:224–239. © 2017 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals, Inc. on behalf of Society of Environmental Toxicology & Chemistry (SETAC)

Key Points
A probabilistic risk assessment using refined exposure modeling was conducted on 3 endangered species residing in California, USA. Based on all lines of evidence, malathion is not expected to result in direct effects to the species, or indirect effects due to effects on fish and invertebrate prey.
The importance of bladder volume in the ultrasound diagnosis of placenta accreta spectrum disorders
Authors: Maynard Henry , Zamudio Stacy , Jauniaux Eric , Collins Sally L. 
Published: October 2017

AbstractObjectiveTo assess how a quantifiable measure of vascularity—i.e. abnormal confluence (Acon) in the subplacental myometrium observed by three‐dimensional power‐Doppler ultrasonography—changes with different bladder volumes.MethodsIn a prospective observational study, women referred to a tertiary UK center with suspected PAS disorders were recruited between August 2016 and May 2017. The largest area of confluent three‐dimensional power‐Doppler signal (Acon) at the uteroplacental interface was estimated under two bladder volumes differing by at least 200 mL.ResultsAcon was calculated for 14 women, of whom seven were subsequently found to have PAS disorders. For these seven women, log(Acon) was significantly greater when measured with a filled bladder than when measured with an unfilled bladder (P<0.001).ConclusionObjective evidence was found for a quantifiable difference in vascularity in the myometrium with bladder volume among women with PAS disorders. This difference has sufficient magnitude to influence the potential of Acon as a diagnostic marker.
Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors
Authors: Minar Lubos , Felsinger Michal , Cermakova Zdenka , Zlamal Filip , Bienertova‐Vasku Julie 
Published: October 2017

AbstractObjectiveTo compare the Copenhagen Index (CPH‐I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors.MethodsIn a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data.ResultsAmong 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P>0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH‐I showed a sensitivity of 69% at a specificity of 85%.ConclusionCPH‐I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.
Leveraging Literacies Through Collaborative, Source‐Based Planning and Teaching in Social Studies and Language Arts
Authors: Patterson Nancy , Weaver Joanna , Fletcher Jamie , Connor Bryce , Thomas Angela , Ross Cindy 
Published: October 2017

AbstractThe value of preparing students for college, careers, and civic life is a shared outcome of social studies and language arts teachers. This study explores how developing content and civic literacy to these ends can be fortified through language arts and social studies teacher collaboration in source‐based planning and teaching. Although numerous studies of the positive impacts of coplanning have been conducted, there has been less focus on the actual implementation of the teachers’ collaborative plans and teachers’ perceptions of their impact. Through examination of teachers’ plans and follow‐up interviews about implementation, researchers found that teachers both planned and implemented inquiry‐based, collaborative plans using sources to promote various types of literacy and that the collaboration increased student interest and inquiry in social studies and integrated language arts. Teachers’ perceptions of the impacts of the collaboration on students’ literacy skills were positive.
Fabrication of Bioactive Fiber‐reinforced PEEK and MXD6 by Incorporation of Precursor of Apatite
Authors: Yabutsuka Takeshi , Fukushima Keito , Hiruta Tomoko , Takai Shigeomi , Yao Takeshi 
Published: October 2017

AbstractWe aimed to develop an effective process to provide bioactivity to carbon fiber‐reinforced polyetheretherketone (PEEK), glass fiber‐reinforced PEEK and glass fiber‐reinforced poly(m‐xylyleneadipamide)‐6 (MXD6), possessing similar elastic modulus to cortical bone in this study. First, we formed fine pores on the surface of each substrate by a short‐time sulfuric acid treatment. Second, in order to provide hydrophilic property, we treated the surfaces of each substrate with oxygen plasma. Finally, we deposited fine particles of amorphous calcium phosphate (PrAp) in the pores by soaking each substrate in SBF adjusted at pH 8.40, 25.0°C, and subsequently kept at 70.0°C for 24 h. By this treatment, we obtained the bioactive fiber‐reinforced polymers. By soaking thus‐obtained each material in SBF, apatite formation was induced on the whole surface of each substrate within 1 day by PrAp deposited in the pores and high apatite‐forming ability was performed on each material. The adhesive strength between the apatite layer showed high value by mechanical anchoring effect generated by the apatite formed in the pores. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 2254–2265, 2018.
Practical experiences from the bench‐scale implementation of a bioprocess for fucoxanthin production
Authors: Gómez‐Loredo Alma , González‐Valdez José , González‐González Mirna , Benavides Jorge , Rito‐Palomares Marco 
Published: October 2017

AbstractBACKGROUNDA laboratory‐scale protocol for the production, primary recovery and partial purification of fucoxanthin via biomass production at low light intensities was previously reported. This proposed approach exploited the use of ethanol salt aqueous two‐phase systems (ATPS) and ultrafiltration (UF) to deliver a 45% total recovery yield if all steps were implemented in a bioprocess. In this study, practical experiences derived from the bench‐scale implementation of the previously characterized lab protocol are presented.RESULTSAfter implementation of the process, a 47.5% fucoxanthin recovery was obtained, while 87.2% of the contaminant proteins were removed.CONCLUSIONThe findings reported here provide the required guidelines to facilitate process scale‐up for the potential commercial production and recovery of fucoxanthin. © 2017 Society of Chemical Industry
Harvesting of microalgae Coelastrella sp. FI69 using pore former induced TiO2 incorporated PES mixed matrix membranes
Authors: Yogarathinam Lukka Thuyavan , Gangasalam Arthanareeswaran , Ismail Ahmad Fauzi , Parthasarathy Prakash 
Published: October 2017

AbstractBACKGROUNDExtracellular polymeric substances and microalgae stimulate membrane fouling during harvesting. The objective of the study was to compare the effect of pore formers on TiO2 embedded polyethersulfone mixed matrix membranes (MMMs) to harvest Coelastrella sp. FI69. The study experimented with hydrophilic additive (polyethylene glycol), polyelectrolyte additive (polyethylenimine), inorganic additive (zinc chloride) and charged polymer (sulfonated polyetherether ketone (SPEEK)) as pore formers.RESULTSIt was found that SPEEK/TiO2 combination enhanced the hydrophilic property of the PES membrane surface. Also, contact angle value (55.22°) was decreased by 1.38 times that of a neat PES (76.63°) membrane. Morphology studies indicated that the TiO2 particles dispersed well in the PES membrane matrix along with pore formers. The existence of super hydrophilic TiO2 supported the restriction of microalgae cell attachment on the membrane surface. The filtration of alginic acid sodium solution analysis showed that PES/SPEEK/TiO2 and PES/PEG/TiO2 membranes support higher flux with minimal fouling percentage. Microalgae filtration studies indicated that synergistic effect of both SPEEK and TiO2 on PES membrane exhibited higher water recovery percentage of 96% and equilibrium flux of 66 L m‐2 h‐1.CONCLUSIONFouling propensity is significantly reduced in modified membranes. Future research on scale‐up of membranes for further microalgae dewatering applications is recommended. © 2017 Society of Chemical Industry
Biofiltration of formaldehyde, acetaldehyde, and acrolein from polluted airstreams using a biofilter
Authors: Jamshidi Arsalan , Hajizadeh Yaghoub , Amin Mohammad‐Mehdi , Kiani Ghasem , Haidari Reza , Falahi‐Nejad Kheibar , Parseh Iman 
Published: October 2017

AbstractBACKGROUNDAldehydes inhalation can adversely affect human and environmental health. This study was carried out to investigate the removal efficiency (RE) of three aldehydes including formaldehyde (FA), acetaldehyde (ACT), and acrolein (ACR) from airstreams using a biofilter packed with a new mixture of compost‐scoria‐sugarcane bagasse. Influence of inlet concentrations (0.63–25.15 mg/m3), empty bed residence time (EBRT) (40, 80, and 120 s), and bed height on the biofilter efficiency were measured for three separate 90‐day periods.RESULTSThe mean RE of FA, ACT, and ACR were 92.6 ± 4.6, 85.3 ± 6.2, and 86.3 ± 5.7%, respectively. The mean RE at EBRTs of 40, 80, and 120 s was 84.9 ± 6.1, 87.9 ± 6.2, and 91.4 ± 5.1%, respectively. Results showed that the RE decreased with increasing inlet concentration, so that the minimum RE (80.2 ± 4.7%) was observed at the inlet concentration of 78.5–25.15 mg m‐3. Also, more than 68% of the overall RE occurred in section 1 of the biofilter, where the mean bacterial population (7.51 log10CFU g‐1) was higher than that in section 2 (7.02 log10CFU g‐1).CONCLUSIONSOwing to the high RE and negligible pressure drop of the bed, it can be concluded that a biofilter with the same conditions is a satisfactory technique to remove aldehydes from polluted air. © 2017 Society of Chemical Industry
Aggressive nutrition intervention reduces ascites and frequency of paracentesis in malnourished patients with cirrhosis and ascites
Authors: Vidot Helen , Bowen David G , Carey Sharon , McCaughan Geoffrey W , Allman‐Farinelli Margaret , Shackel Nicholas A 
Published: October 2017

Background and AimAlterations in nutrient metabolism, nutritional requirements, and reduced dietary intakes are common in chronic liver disease (CLD). These result in malnutrition, sarcopenia, and exacerbate progression to decompensation and ascites. We aimed to investigate the effects of continuous tube feeding (TF) on nutritional status and levels of ascites in malnourished individuals with decompensated cirrhosis.MethodsFourteen malnourished patients with decompensated cirrhosis and ascites who failed to respond to standard oral nutritional interventions received supplementary continuous nasogastric TF for 7 ± 1 weeks. Liver disease severity was assessed by model for end‐stage liver disease (MELD) and Child–Turcotte–Pugh (CTP) scores.ResultsContinuous TF occurred at home for 7 weeks (1.5–12 weeks). Prior to feeding, 12 patients had severe ascites, 10 required paracentesis, and 13 were severely malnourished. At completion of TF, five patients did not have ascites, four had mild ascites, four had moderate ascites, and only one had severe ascites and 10 no longer required paracentesis (P < 0.001). Median patient survival was 26 ± 7 months. Five survived to transplantation and three remained transplant‐free at 8, 1.9, and 1.7 years. Seven patients were moderately malnourished at completion of TF with an overall improvement in hand grip strength from 51% to 65% of predicted (P = 0.02).ConclusionSupplementary continuous TF may help to reduce ascites and paracentesis requirements and improve nutritional status. Supplementary continuous TF should be considered as a treatment for malnourished patients with decompensated cirrhosis and refractory ascites.
“Patient reported outcomes” following experimental surgery—using telemetry to assess movement in experimental ovine models
Authors: Newell Karin , Chitty Jose , Henson Frances M. 
Published: October 2017

ABSTRACTMany potential treatments for orthopedic disease fail at the animal to human translational hurdle. One reason for this failure is that the majority of pre‐clinical outcome measurements emphasize structural changes, such as gross morphology and histology, and do not address pain or its alleviation, which is a key component of treatment success in man. With increasing emphasis on “patient reported outcome measurements (PROM)” in clinical practice, in this study we have used two different telemetric methods (geolocation and Fitbark activity trackers, Kansas City, MO) to measure movement behavior, i.e., an indirect PROM, in an ovine osteoarthritis induction and an osteochondral defect model performed in adult female Welsh Mountain sheep. This study demonstrates that both systems can be used to track movement and activity of experimental sheep before and after surgery and that the Geolocator system recorded a decrease in distance moved and activity at the end of the experimental period in both models. The Fitbark activity tracker also recorded significant alterations in movement behavior at the end of these studies and this method of recording showed a correlation between Fitbark data and radiography, macroscopic and histological scoring (well recognized outcome measurements), particularly in animals with large (10 mm) defects, i.e., more severe pathology. These results suggest that telemetry is able to track movement behavior in experimental sheep and that the methodology should be considered for inclusion in outcome measures in preclinical orthopedic research. © 2017 The Authors. Journal of Orthopaedic Research® Published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 36:1498–1507, 2018.
3‐dimensional metrics of proximal femoral shape deformities in Legg–Calvé–Perthes disease and slipped capital femoral epiphysis
Authors: Chan Elaine F. , Farnsworth Christine L. , Klisch Stephen M. , Hosalkar Harish S. , Sah Robert L. 
Published: October 2017

ABSTRACTLegg–Calvé–Perthes disease (LCPD) and slipped capital femoral epiphysis (SCFE) are two common pediatric hip disorders that affect the 3‐dimensional shape and function of the proximal femur. This study applied the principles of continuum mechanics to statistical shape modeling (SSM) and determined 3‐D metrics for the evaluation of shape deformations in normal growth, LCPD, and SCFE. CT scans were obtained from 32 patients with asymptomatic, LCPD, and SCFE hips ((0.5–0.9 mm)2 in‐plane resolution, 0.63 mm slice thickness). SSM was performed on segmented proximal femoral surfaces, and shape deformations were described by surface displacement, strain, and growth plate angle metrics. Asymptomatic normal femurs underwent coordinated, growth‐associated surface displacements and anisotropic strains that were site‐specific and highest at the greater trochanter. After size‐ and age‐based shape adjustment, LCPD femurs exhibited large displacements and surface strains in the femoral head and neck, with associated changes in femoral head growth plate angles. Mild SCFE femurs had contracted femoral neck surfaces, and surface displacements in all regions tended to increase with severity of slip. The results of this paper provide new 3‐D metrics for characterizing the shape and biomechanics of the proximal femur. Statement of Clinical Significance: Quantitative 3‐D metrics of shape may be useful for understanding and monitoring disease progression, identifying target regions for shape modulation therapies, and objectively evaluating the success of such therapies. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1526–1535, 2018.
Searching for trial protocols: A comparison of methods
Authors: Sutton Anthea , Galvan De La Cruz Maria Carmen , Leaviss Joanna , Booth Andrew 
Published: October 2017

IntroductionRegistration and publication of trial protocols has become increasingly important and a requirement in some sources of funding and publication. Increased access to protocols yields many potential benefits, but there are issues regarding identification of published protocols. The aim of this investigation is to compare methods of retrieval for identifying trial protocols in a systematic review.MethodsSix stages of searching (checking published trial reports, searching journal Web sites, Internet searching, trial registers, bibliographic databases, and contact with authors) were completed to identify 74 trial protocols.ResultsFifty‐seven percent of the trial protocols were identified upon completion of all 6 stages of searching. The most comprehensive method was searching trial registers that identified 51% of the protocols. Contact with authors was most effective at uniquely identifying protocols; 12% were retrieved via this single method. Contact with authors was the only effective method of identifying protocols for trials pre‐2005.DiscussionWhen attempting to identify trial protocols to include in systematic reviews, some methods are relatively quick to undertake but deliver a low yield. The most effective search strategy for most sources was retrieval by trial registration number where available.ConclusionsFor protocols of trial results published pre‐2005, review authors should contact authors as a priority. For protocols post‐2005, they should check the trial publication for protocol details, search trial registers, and contact authors, ceasing searching once a predetermined point of diminishing returns has been reached.
CE method for analyzing Salmonella typhimurium in water samples
Authors: Arce Cristina , Cahya‐Mawarda Panji , Arroyo‐Manzanares Natalia , Garrido Juan J. , Arce Lourdes 
Published: October 2017

AbstractSalmonella typhimurium is commonly described as a food‐borne pathogen. However, natural and drinking water are known to be important sources for the transmission of this pathogen in developing and developed countries. The standard method to determine Salmonella is laborious and many false positives are detected. To solve this, the present work was focused on the development of a capillary zone electrophoresis method coupled to ultraviolet detection for determination of Salmonella typhimurium in water (mineral and tap water). Separations were performed in less than 11 minutes using 4.5 mM Tris (hydroxymethyl)‐aminomethane, 4.5 mM boric acid and 0.1 mM ethylene diamine tetraacetate (pH 8.4) with 0.1% v/v poly ethylene oxide as separation buffer. The precision of the method was evaluated in terms of repeatability obtaining a relative standard deviation of 10.5%. Using the proposed method Salmonella typhimurium could be separated from other bacteria that could be present in water such as Escherichia coli. Finally, the proposed methodology was applied to determine Salmonella typhimurium in tap and mineral water.
Upper airway stimulation therapy and prior airway surgery for obstructive sleep apnea
Authors: Mahmoud Ahmad F. , Thaler Erica R. 
Published: October 2017

ObjectiveTo determine if patients with prior airway surgery for obstructive sleep apnea (OSA) had increased benefit following implantation with hypoglossal nerve stimulator.Study DesignRetrospective chart review at a single institution tertiary academic care center.MethodsFollowing implantation with hypoglossal nerve stimulator device, the outcomes of patients who underwent prior airway surgery for OSA were compared with those who did not. Primary outcome measures included apnea‐hypopnea index (AHI) and nadir oxyhemoglobin saturation (NOS) as measured by polysomnography. Secondary outcome measures included Epworth Sleepiness Scale.ResultsForty‐seven patients underwent implantation with hypoglossal nerve stimulator. Of these, 30 patients had undergone prior airway surgery for OSA, whereas 16 did not. Mean preoperative AHI and NOS were 39.3 ± 2.8 and 78% ± 1.8% for all patients, 39.4 ± 3.7 and 79% ± 14% for patients with prior airway surgery, and 39.1 ± 4.0 and 77% ± 2.6% for patients without prior surgery. Mean postoperative AHI and NOS were 3.9 ± 1.2 and 91% ± 0.4% for all patients, 4.2 ± 1.7 and 91% ± 0.5% for patients with prior surgery, and 3.4 ± 1.5 and 93% ± 0.6% for patients without prior surgery (P = 0.756 and 0.053, respectively).ConclusionOverall, patients had significant improvement following implantation with hypoglossal nerve stimulator. Prior airway surgery had no statistically significant effect on postoperative AHI or NOS.Level of Evidence4. Laryngoscope, 128:1486–1489, 2018