bluuebunny/crossref_metadata_2025_split huggingface dataset:
S11-1: How to reach women in difficult life situations and encourage their participation in physical activity: Insights from urban and rural areas
Authors: Till Maike , Abu-Omar Karim , Ziemainz Heiko 
Published: September 2024

Abstract

Purpose
The community-based participatory research project “BIG” aims to empower socially disadvantaged women (e.g. single-mothers, unemployed women) to engage in physical activity (PA) and exercise. These women face barriers to exercise, such as high registration fees, limited childcare options, and culturally insensitive programs. This study explored various approaches to reaching these women and compared strategies between rural and urban areas.

Methods
Over the last three years, two cities and three rural districts in Bavaria, Germany, have adopted the BIG project, previously implemented in 17 cities. As part of the intervention-study, project coordinators participated in annual individual interviews with a specific focus on reaching women. A total of 11 interviews were transcribed and analyzed using an inductive qualitative content-analysis, assisted by MAXQDA software, to address the research objective.

Results
Preliminary results suggest that women facing difficult life situations (e.g., being unemployed, single mothers or from a different cultural background) are more readily reached in urban settings compared to rural areas. This can be attributed to the better-equipped structures and networks present in urban areas. Cities usually have specific meeting points, such as women's centers, support centers for immigrants and asylum seekers, or integration officers. In rural areas, the engagement of individual volunteers is crucial, especially leaning on the efforts of pivotal figures within each community. These individuals contribute their networks and expertise to support these initiatives, having earned the trust of the citizens. While individual 'champions' are influential in both rural and urban areas, their efforts and the trust they establish play a more significant role in rural areas.

Conclusions
The study results highlight the necessity for distinct approaches, particularly in rural areas. Subsequent initiatives should prioritize devising methods to implement projects in these regions and employ strategies to reach women facing difficult life situations, especially those residing away from existing services.

Support/Funding Source
This study was funded by the GKV-Bündnis for health.
S11-2: Reaching and recruiting young people experiencing homelessness for physical activity interventions: Challenges, opportunities, and recommendations
Authors: Thomas Jennifer , Crone Diane , Bowes Nicola , Thirlaway Katie , Meyers Robert W , Mackintosh Kelly A 
Published: September 2024

Abstract

Purpose
There is a growing body of evidence to suggest that physical activity-based interventions may be effective for engagement, psychological outcomes, and behaviour change of young people experiencing homelessness (YPEH). Nonetheless, challenges associated with reaching and recruiting this marginalised population are frequently reported owing to social isolation, lack of trust, and a high prevalence of poor mental health. This study sought to explore common barriers to recruitment, and identify potential strategies through which these may be overcome.

Methods
Three 8-week physical activity interventions were delivered to groups of between 4 and 12 YPEH. Following each intervention, qualitative data was collected through a series of interviews with implementers (sports coaches; n = 5) and support staff (n = 3), and three focus groups with participants (n = 17). Documented feedback, such as informal correspondence with staff, were used to provide further insights. Data were transcribed verbatim and analysed using a mixed inductive/deductive thematic approach to identify multi-level challenges and opportunities, and comprehensively address the research aims.

Results
Multiple barriers and opportunities to the reach and recruitment of YPEH were identified across organisational, individual, and intervention levels. Challenges included limited staffing and organisational resources, negative experiences of participants, and sub-optimal intervention design and materials. Enablers included co-production with stakeholders, organisational staff champions, participant incentives, appropriate materials, and an active outreach recruitment strategy.

Conclusions
Overcoming challenges associated with reaching and recruiting marginalised groups for physical activity interventions requires consideration of multi-level barriers from the early stages of intervention development. While the enablers identified are concurrent with those reported across wider literature, future research should focus on how these can be embedded in a co-productive manner involving all stakeholders, throughout the research process.

Support/Funding Source
Knowledge Economy Skills Scholarships (KESS 2); European Social Research Council Postdoctoral Fellowship Programme.
S14-4: Designing a physical activity pathway in healthcare model for Irish Health Services
Authors: O’Brien Sarah , Casey Blathin , Cotter Eimear 
Published: September 2024

Abstract

Background
There is strong evidence for health benefits of regular physical activity (PA) for preventing non-communicable diseases and reducing risk factors as well as improving mental, physical, and emotional health for those living with chronic diseases. There is not a consistent, coherent mechanism to connect patients in primary care with supports and services to be more physically active currently within the Irish public health service.

Purpose
To design a physical activity pathway, and identify the supporting infrastructure required to enable implementation across the Irish public health system, with a particular focus on primary care.

Methods
Using HSE Change Management Guide, the HSE Healthy Eating Active Living Programme commenced a project to co-design a pathway and identify essential infrastructure to support implementation of the pathway across the Irish public health system. Stakeholders engaged in the co-design process include health professionals, health service planners and managers, Local Sports Partnerships, Sport Ireland as well as the public who are potential service users.

Results
A range of methods including interviews, focus groups and workshops were used to gather insights from stakeholders and potential service users to inform the service design. The COM-B model was used as an underpinning behaviour change theoretical framework to analyse the insights including the use of APEASE criteria to prioritise components for the service design.

Conclusions
Establishing a physical activity pathway in healthcare model in a public health service is a complex process. Using a structured change management process, with a strong focus on stakeholder engagement to facilitate co-design may increase success of implementation.

Practical implications
This work will result in a coherent, consistent, resourced process to connect service users in the Irish public health service with appropriate community based, publicly funded physical activity opportunities.

Funding
The Health Services Executive, Ireland
S15 Promoting Physical Activity and Health in Sports Clubs: the what, the why and the how!
Authors: Van Hoye Aurélie , Seghers Jan 
Published: September 2024

Abstract

Purpose
The symposium will discuss the relationship between health and sport, to enlighten current configurations, as well as on how to foster the relationships between the two concepts.

Methods
Four presentations are foreseen in the symposium. First, Susanna Geidne (Örebro University, Sweden) will tackle the what by introducing four core concepts (health promotion as an outcome of sport, in sport, through sport and health promoting sport), their stakes and challenges in terms of application. Second, Jenifer Gothilander (Mälardalen University, Sweden) will explore the why by describing participations patterns in organised and unorganised sport among adolescents in Sweden. The two last presentation will highlight the how of physical activity and health promotion in organised sport. Third, Catherine O’Sullivan (World Athletics, Monaco) will showcase how physical activity is fostered among World Athletics activities. Fourth, Kevin Barros (Université de Lorraine, France) will present results of a literature review on coaches’ health promotion skills, strategies and training needs.

Results
Participants will learn that health promotion in sport is not given and better understand the difference between fostering health through sport and being health promoting, how to adapt policies to tackle participants trends, how to best organise sport events and activities to foster active lifestyle and discover different strategies that coaches adopt to promote health based on their communication, motivation or management skills.

Conclusion
Finally, Aurélie Van Hoye (University of Limerick, Ireland) and Jan Seghers (Katholieke Universiteit Leuven, Belgium) will engage the conversation with the audience on how to better root physical activity and health promotion by taking organised sport contexts into account.
S15-1: Sports clubs as health promotion settings: From physical activity to sustainable sport - a question of how!
Authors: Geidne Susanna , Ericson Helena , Quennerstedt Mikael , Van Hoye Aurélie 
Published: September 2024

Abstract

Purpose
The concepts of public health, health and health promotion have been used for decades in relation to sport in policy, research and practice. That sport has some kind of significance for and connection to public health is clear. But how can we understand the relationships between sport and public health?
The aim of this presentation is to argue that what is regarded as knowledge about the relationship between sport and public health largely depends on how the concepts of public health, health, health promotion and sport are framed.

Methods
In this presentation, we theorize the relationship between sport and public health as different patterns and give examples of how sports clubs can thus act as a health-promoting setting for different target groups.

Results
A first attempt to categorize the patterns in the four categories (i) health promotion as an outcome of sport, (ii) health promotion through sport, (iii) health promotion in sport, and (iv) health promoting sport. In these four categories we reveal research, that because of how they define health promotion and sport, are quite different. The different categories also use the concept of sport differently, as something that will always be healthy because it contains physical activity, as a mean, as an arena where you reach people or in a more integrated way.

Conclusions
We argue that it is not enough to recognize that physical activity and sport are good for people's physical health. By using a more inclusive conceptualization of how health can be promoted in, through and as health-promoting sport, health promotion studies can feed into the conclusions of other studies, i.e. what can be done about the how-question. What we propose and provide empirical examples of in this presentation can be seen as a theoretical basis for discussing the relationship or relationships between sport and public health that can be used in policy, research and practice. It is therefore possible to broaden the issue, to make it more complex, to go beyond compartmentalized thinking and to contribute to sustainable change in sport. Because, sustainable sport can be a question of how!

Support/Funding Source
None
S16-1 Get Finland Moving programme
Authors: Aalto-Nevalainen Päivi 
Published: September 2024

Abstract

Purpose
With the introduction of the new governmental programme, the Finnish Government targets to increase physical activity across all age groups. To accomplish this goal, a comprehensive cross-administrative initiative called the 'Get Finland Moving' programme has been initiated, aiming to promote physically active lifestyles. The program is grounded in phenomenon-based thinking and leveraging a thorough evaluation of the branches within each of the 12 Ministries. This evaluation assessed each Ministrýs relationships, roles, and opportunities to promote physical activity within society.

Project or policy description
Over the past years, Finland has developed a comprehensive, well-managed package dedicated to promoting physical activity across all age groups. The 'Get Finland Moving' programme is poised to further fortify and expand the cross-administrative initiatives aimed at increasing physical activity. The government executes the action plan through various measures, such as reinforcing physically active practices in early childhood education, schools, and educational institutes. Additionally, integrating physical activity into the development of work ability and workplaces is a key focus. Steps will be taken to enhance physical activity promotion skills and competence in different educational sectors, including healthcare, social welfare, and education sciences. Efforts will also be directed towards improving lifestyle counselling and physical activity guidance in municipalities and well-being service counties.
Furthermore, initiatives include adding a ball to the maternity pack and increasing the provision of advice on physical activity for families at maternity and child health clinics. The promotion of physically active lifestyles will be incorporated into the Act on Primary and Lower Secondary Education, as well as in the reform of land use legislation. Additionally, measures involve exploring and evaluating options for promoting physical activity through taxation and examining the feasibility of guaranteeing a subjective right to outdoor recreation for older people.

Conclusion
One distinctive aspect of the programme is its management and monitoring at the government level, with measures intricately aligned with the diverse administrative branches of various ministries. Another noteworthy feature involves a meticulous analysis of how different administrative branches are connected to the promotion of physical activity.
S16-4 SLOfit Lifelong: citizen science approach to promote and maintain physical fitness and physical literacy across the lifespan
Authors: O'Hehir Colin , Brosnan Paul 
Published: September 2024

Abstract

Purpose
SLOfit Lifelong is a public health initiative which was created to upgrade a well-established, national physical fitness surveillance system for Slovenian schoolchildren that has been collecting annual fitness data for over three decades.

Project or policy description
The ultimate objective of creating SLOfit Lifelong was to build a modern societal infrastructure with the capacity and ability to detect future causal associations between childhood physical fitness trends and future health outcomes based on the lifelong surveillance of one's own fitness status. By instilling citizens with an ambition to test, understand, and follow-up their own physical fitness and health status (including related health risk factors), this initiative provides the technical support and expert feedback needed to engender greater individual control over understanding (and thus modulating), one's own physical fitness status as they progress into older adulthood.

Conclusions
Through its sophisticated online web application My SLOfit, social media, print media, and outreach workshops, SLOfit Lifelong provides the expert support for public health engagement by fostering positive lifelong physical literacy experiences an individual can enjoy across their aging journey.
251 Development of the Physical Activity Messaging Guide to Enhance Messaging Practice across HEPA Nations
Authors: Williamson Chloë 
Published: September 2024

Abstract

Purpose
Physical activity (PA) messaging can help change individual and social factors, and thus contribute to improving PA levels, but improving PA messaging practice is warranted. In 2021, the Physical Activity Messaging Framework was published following a robust modified Delphi study. One purpose of this framework is to aid creation of new PA messages. However, a need to enhance dissemination and uptake of this framework in day-to-day practice was identified. Therefore, this project aimed to translate the principles of the framework to develop a practitioner-friendly messaging guide.

Methods
The framework was adapted and combined with existing evidence to create a step-by-step guide; the Physical Activity Messaging Guide (PAMG). Following this, formal feedback on PAMG was sought through online and in person meetings with members of HEPA/WHO Europe. This feedback was acted on to develop a further draft, which was shared more widely via an online, open-questioned survey (Qualtrics) to gather broader feedback.

Results
At time of writing, feedback has been gathered from 39 individuals via online survey. Responses were gathered from the UK (including Scotland, Northern Ireland, and England), the United States, Ireland, Germany, Romania, Spain, Portugal, Canada, Australia, and Finland, and came from a mixture of academics, exercise professionals, healthcare professionals, practitioners, and other (e.g., education) professions. Feedback was overall positive, with constructive recommendations for further refinement. Amendments are underway based on feedback to develop a final version of the PAMG, which will be presented at the HEPA 2024 Conference in Dublin, Ireland. Key next steps include translation of the guide into different languages to further enhance uptake.

Conclusions
Involvement in the Early Career Professional Development Programme has enabled a collaborative approach to develop and refine the PAMG. The PAMG will, as a result, be a more useful tool to various users across countries and contexts. If the PAMG is applied consistently in messaging practice, developed PA messages will be more evidence-based and target-audience focused, ultimately contributing to improving population levels of PA.

Funding Source
N/A. This work was completed as part of CW’s appointment to the HEPA/WHO Europe Early Career Professional Development Programme 2024.
Phosphorylation of RelA/p65 Ser536 inhibits the progression and metastasis of hepatocellular carcinoma by mediating cytoplasmic retention of NF-κB p65
Authors: Zuo Wentao , Ma Haoyang , Bi Jianghui , Li Tiaolan , Mo Yifeng , Yu Shiyu , Wang Jia , Li Beiqing , Huang Jinfeng , Li Yongwen , Li Li 
Published: September 2024

Abstract

Background
Intrahepatic and extrahepatic metastases contribute to the high recurrence rate and mortality of hepatocellular carcinoma (HCC). Constitutive activation of nuclear factor-κB (NF-κB) is a crucial feature of HCC. NF-κB p65 (p50–p65) is the most common dimeric form. Ser536 acts as an essential phosphorylation site of RelA/p65. However, the effect of RelA/p65 Ser536 phosphorylation on progression and metastases during intermediate and advanced HCC has not been reported.

Methods
Phosphorylation of RelA/p65 (p-p65 Ser536) and NF-κB p65 were detected by using immunohistochemical staining in HCC tissue samples. The biological effects of RelA/p65 Ser536 phosphorylation were evaluated by using xenograft and metastasis models. NF-κB p65 nuclear translocation was detected by using Western blotting. The binding of NF-κB p65 to the BCL2, SNAIL, and MMP9 promoters was detected by using chromatin immunoprecipitation. The biological effects on proliferation, migration, invasion, and epithelial–mesenchymal transition were assessed by using tetrazolium-based colorimetry, colony formation, EdU incorporation, flow cytometry, cell wound healing, and transwell assay.

Results
NF-κB p65 is highly expressed, while p-p65 Ser536 is not well expressed in intermediate and advanced HCC tissues. In vivo experiments demonstrated that a phosphorylation-mimetic mutant of RelA/p65 Ser536 (p65/S536D) prevents tumor progression and metastasis. In vitro experiments showed that p65/S536D inhibits proliferation, migration, and invasion. Mechanistically, RelA/p65 Ser536 phosphorylation inhibits NF-κB p65 nuclear translocation and reduces NF-κB p65 binding to the BCL2, SNAIL, and MMP9 promoters.

Conclusions
RelA/p65 Ser536 phosphorylation was detrimental to NF-κB p65 entry into the nucleus and inhibited HCC progression and metastasis by reducing BCL2, SNAIL, and MMP9. The phosphorylation site of RelA/p65 Ser536 has excellent potential to be a promising target for NF-κB-targeted therapy in HCC.
Biofilms inactivate the free-living stage of Batrachochytrium dendrobatidis, the most destructive pathogen for vertebrate diversity
Authors: Sentenac Hugo , Schmeller Dirk S , Caubet Solène , Carsin Adélaïde , Guillet Rémi , Ferriol Jessica , Leflaive Joséphine , Loyau Adeline 
Published: September 2024

Abstract
Emerging infectious diseases threaten biodiversity and human health. Many emerging pathogens have aquatic life stages and all immersed substrates have biofilms on their surface, i.e. communities of microorganisms producing a gelatinous matrix. However, the outcome of the interactions between environmental biofilms and pathogens is poorly understood. Here, we demonstrate that biofilms reduce the survival of the most impactful pathogen for vertebrate diversity, the invasive chytrid fungus Batrachochytrium dendrobatidis. Effects on its zoospores varied with biofilm composition in controlled settings and biofilm compositional variation also coincided with divergent impacts of chytridiomycosis on amphibian populations in nature. Our results suggest that biofilms form a biotic component of ecosystem resistance to Batrachochytrium dendrobatidis by reducing environmental transmission, and that they could be used to develop nature-based technologies to limit the impacts and spread of this invasive chytrid fungus. Our study warrants further research into the interactions between environmental biofilms and pathogenic and/or invasive micro-organisms.
The Impoverishment of Psychiatric Knowledge
Authors: Aftab Awais , Fava Giovanni Andrea 
Published: September 2024

Abstract
Giovanni Andrea Fava, MD, served as Associate Professor of Psychosomatic Medicine and then Professor of Clinical Psychology at the University of Bologna in Italy until the end of 2018. He is currently Clinical Professor of Psychiatry at the State University of New York (SUNY) at Buffalo, NY. He is the author of Discontinuing Antidepressant Medications (Oxford University Press, 2021). Fava’s scientific contributions to psychiatry are manifold, but his work on iatrogenic comorbidity and oppositional tolerance in psychopharmacology has received particular attention in the critical psychiatry community. For 30 years (1992–2022) he was Editor-in-Chief of the journal Psychotherapy and Psychosomatics. This interview discusses the neglect of clinical practice as a source of fundamental research questions, iatrogenic comorbidity, oppositional tolerance with use of antidepressants, and the brewing intellectual crisis in medicine and psychiatry.
Dementia Due to Other Medical Conditions
Authors: Sofko Channing A. , Naman Katya 
Published: September 2024

Abstract
This chapter provides an overview of cognitive impairment in older adult populations due to medical conditions that have not been addressed in previous chapters. It emphasizes the importance of thoroughly assessing all potential medical conditions that may contribute to cognitive decline via conducting thorough medical record reviews and clinical interviews. Specifically, it is essential to consider reversible causes of cognitive impairment and to determine if medical conditions may be contributing to, or explaining, cognitive and psychiatric symptoms. Equally important is evaluating the progression of cognitive changes over time and obtaining collateral reports when permitted. This chapter focuses on traumatic brain injury (TBI), multiple sclerosis (MS), and cognitive impairment secondary to endocrine dysfunction. This chapter concludes with comments on improvements in the management of human immunodeficiency virus (HIV) and the associated impact on cognition.