bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Transition‐Metal‐Free Self‐Hydrogen‐Transferring Allylic Isomerization.
Authors: Zheng Hong‐Xing , Xiao Zu‐Feng , Yao Chuan‐Zhi , Li Qiang‐Qiang , Ning Xiao‐Shan , Kang Yan‐Biao , Tang Yong 
Published: April 2016

AbstractA phenanthroline/tBuONa‐catalyzed allylic isomerization of alcohols (I) and amines (III) is described.
ChemInform Abstract: Dual Gold/Photoredox‐Catalyzed C(sp)—H Arylation of Terminal Alkynes with Diazonium Salts.
Authors: Tlahuext‐Aca Adrian , Hopkinson Matthew N. , Sahoo Basudev , Glorius Frank 
Published: April 2016

AbstractThe title reaction is carried out under base‐free conditions, generally under visible light (household sources or sunlight), which allow the generation of an Au(I)/Au(III) redox cycle.
ChemInform Abstract: Efficient Synthesis and Electronic Spectra of Unsymmetrical 5,12‐Diethynyltetracene Derivatives.
Authors: Iwanaga Tetsuo , Yamamoto Yuta , Nishioka Keita , Toyota Shinji 
Published: April 2016

AbstractThe unsymmetrical title tetracenes bearing phenyl or trialkylsilyl groups are easily obtained in one‐pot from tetracenequinone by two addition reactions with ethynyl lithium reagents followed by reductive aromatization.
ChemInform Abstract: Eco‐Friendly Strategy: Design and Synthesis of Biologically Potent Benzimidazole—Amine Hybrids via Visible‐Light Generated Oxidative C—H Arylamylation of Analenic Amidines.
Authors: Siddiqui I. R. , Ibad Farah , Ibad Afshan , Waseem Malik Abdul , Watal Geeta 
Published: April 2016

AbstractRing‐opening of benzimidazoles in the presence of amines gives o‐anilinic amidine intermediates, which cyclize to form 2‐aminobenzimidazoles.
ChemInform Abstract: Copper‐Catalyzed Domino Synthesis of 2‐Arylthiochromanones Through Concomitant C—S Bond Formations Using Xanthate as Sulfur Source.
Authors: Sangeetha Subramani , Muthupandi Pandi , Sekar Govindasamy 
Published: April 2016

AbstractThis domino process proceeds through Cu‐catalyzed C(aryl)—S bond formation by coupling of xanthate with 2‐iodochalcones followed by thioester C—S bond cleavage and subsequent S—C bond formation via intramolecular Michael addition.
ChemInform Abstract: Copper‐Mediated C(sp3)—H Amination in a Multiple C—N Bond‐Forming Strategy for the Synthesis of N‐Heterocycles.
Authors: Xie Zeqiang , Peng Jiangling , Zhu Qiang 
Published: April 2016

AbstractA synthesis of imidazo[1,5‐a]pyridines through a three‐component reaction involving benzyl substituted pyridines, aldehydes, and TMSN3 is developed.
ChemInform Abstract: Synthesis of Novel, Functionalized Tricycles Utilizing the Interrupted Pummerer Reaction.
Authors: Boyd Scott , Davies Robert D. M. , Degorce Sebastien L. , Groombridge Sam , S. Scott James , Stokes Stephen 
Published: April 2016

AbstractThe synthesis of novel functionalized pyrrolothiazolo‐pyridines, ‐pyrimidines, and ‐pyrazines is based on interrupted Pummerer reaction to effect cyclization of sulfoxide precursors.
ChemInform Abstract: Synthesis of 2,3‐Dihydro‐1H‐azepine and 1H‐Azepin‐2(3H)‐one Derivatives from Intramolecular Condensation Between Stable Tertiary Enamides and Aldehydes.
Authors: Zhu Wenju , Zhao Liang , Wang Mei‐Xiang 
Published: April 2016

AbstractWith P2O5 as the additive and BBr3 as a Lewis acid catalyst, the title reaction produces a series of azepine structures in good to excellent yields.
Framing the usefulness of eHRM in talent management: A case study of talent identification in a professional services firm
Authors: Wiblen Sharna 
Published: April 2016

AbstractAs talent management evolves from intuitive to evidence‐based decision‐making, the role of electronic Human Resource Management (eHRM) to gather, distribute, and analyze data becomes more critical. However, surprisingly few academic studies investigate the role of technology in talent management. Drawing on a qualitative case study of talent management in a large professional services firm, this paper critically examines how eHRM information technologies are framed as useful within talent identification discourses. The findings reveal two distinct but interrelated sets of processes employed to identify talent and suggest that the perceived usefulness and centrality of eHRM are influenced by how stakeholders shape their understanding of effective talent management. Copyright © 2016 ASAC. Published by John Wiley & Sons, Ltd.
Aminosilane‐Grafted Zirconia–Titiania–Silica Nanoparticles/Torlon Hollow Fiber Composites for CO2 Capture
Authors: Rownaghi Ali A. , Kant Amit , Li Xin , Thakkar Harshul , Hajari Amit , He Yingxin , Brennan Patrick J. , Hosseini Hooman , Koros William J. , Rezaei Fateme 
Published: April 2016

AbstractIn this work, the development of novel binary and ternary oxide/Torlon hollow fiber composites comprising zirconia, titania, and silica as amine supports was demonstrated. The resulting binary (Zr‐Si/PAI–HF, Ti‐Si/PAI–HF) and ternary (Zr‐Ti‐Si/PAI–HF) composites were then functionalized with monoamine‐, diamine‐, and triamine‐substituted trialkoxysilanes and were evaluated in CO2 capture. Although the introduction of both Zr and Ti improved the CO2 adsorption capacity relative to that with Si/PAI–HF sorbents, zirconia was found to have a more favorable effect on the CO2 adsorption performance than titania, as previously demonstrated for amine sorbents in the powder form. The Zr‐Ti‐Si/PAI–HF sample with an oxide content of 20 wt % was found to exhibit a relatively high CO2 capacity, that is, 1.90 mmol g−1 at atmospheric pressure under dry conditions, owing to more favorable synergy between the metal oxides and CO2. The ternary fiber sorbent showed improved sorption kinetics and long‐term stability in cyclic adsorption/desorption runs.
Short message service prompts for skills practice in Internet‐delivered cognitive behaviour therapy for chronic pain – are they feasible and effective?
Authors: Gandy M. , Fogliati V.J. , Terides M.D. , Johnston L. , Nicholson Perry K. , Newall C. , Titov N. , Dear B.F. 
Published: April 2016

AbstractBackgroundPatients face numerous challenges adopting skills taught within pain self‐management programmes. The present study reports the acceptability and preliminary outcomes of supplementing an Internet‐delivered cognitive behavioural therapy (iCBT) course for chronic pain, the Pain Course, with brief automated short message service (SMS) prompts that encourage skills practice.MethodsParticipants were recruited from the Waitlist Control Group of a large randomized controlled trial and provided access to the Pain Course over 8 weeks, with the addition of SMS prompts. Fifteen SMS prompts were created to encourage the use of self‐management skills during the course. Participants were sent one random SMS prompt each business day. The acceptability of the SMS was assessed and clinical outcomes of participants who received prompts (n = 56) compared with a historical group who previously received the course without prompts (n = 139).ResultsSMS prompts were rated highly with 85% reporting them to be very helpful or helpful and that they would recommend them to others. Clinical improvements for those receiving SMS, at post‐treatment and 3‐month follow‐up (disability, d = 0.44; 0.58; anxiety d = 0.50; 0.51; depression, d = 0.78; 0.79 and average pain d = 0.49; 0.54), were consistent with participant who had received the course previously without SMS (ps >0.05).ConclusionsBrief automated SMS prompts were an acceptable adjunct to iCBT for chronic pain but did not result in any additional clinical benefit. Further research is needed to systematically evaluate the potential of SMS prompts to increase skills practice and facilitate treatment outcomes.What does this study add?

Automated short message service (SMS) messages are an acceptable means of prompting skills practice during iCBT for chronic pain.

SMS prompts did not improve clinical outcomes of an established clinician‐supported iCBT programme.
Consumers' preferences for fresh yam: a focus group study
Authors: Barlagne Carla , Cornet Denis , Blazy Jean‐Marc , Diman Jean‐Louis , Ozier‐Lafontaine Harry 
Published: April 2016

AbstractIn West and Central Africa and in the Caribbean, yam is one of the most important sources of carbohydrates and has a great potential to improve food security. The yam production sector is, however, now challenged by the satisfaction of evolving consumers' preferences. Since little is known about consumers' preferences regarding yams' characteristics, product quality, and the drivers of yam purchase, six focus group discussions were conducted (for a total of 31 participants). Among the purchasing criteria, price was considered more important than the others. It was followed by the external damage, the origin, and the size of the tuber. The most frequently cited consumption criteria were the taste, the texture, and color of flesh after cooking. Taste was considered more important than the other criteria. Three consumers' profiles were established reflecting heterogeneity in preferences, especially as concerns the willingness to pay for yam and consumption habits. They were designated as the Hedonistic, the Thrifty and the Flexible. Our results suggest that innovations can be implemented to sustain and stimulate the development of the yam sector in Guadeloupe. Two main development paths were identified. The first path is the valorization of the great existing diversity of yam varieties and the increase in the level of information for consumers about product attributes such as the cooking mode, the origin, and the mode of production. Building a marketing strategy based on the valorization of this diversity can help maintain and preserve yam's agro‐biodiversity and the satisfaction of rapidly evolving consumption habits. The second path is the definition of yam ideotypes that suit consumers' needs. We expect that tailoring the production to consumers' needs will have a positive impact on global food security in the Caribbean region.
Neutrophil and Eosinophil Granule Proteins as Potential Biomarkers of Assessing Disease Activity and Severity in Patients With Ulcerative Colitis
Authors: Li Zhiyan , Long Yan , Bai Mingjian , Li Junxia , Feng Zhenru 
Published: April 2016

BackgroundColonoscopy can assess disease activity and severity of ulcerative colitis (UC) accurately, but it is invasive and costly. Role of noninvasive biomarkers of intestinal inflammation in evaluation of patients with UC is not well understood. In this study, we assessed fecal eosinophil cationic protein (FECP), fecal myeloperoxidase (FMPO), and fecal calprotectin (FC) as surrogate markers of disease activity and severity in patients with UC, and then evaluated effect of the combination of these markers.MethodsSixty‐three UC patients and 59 cases of age‐matched controls were investigated. All patients underwent clinical, endoscopic, and histological assessment for disease activity and severity. Fecal samples were analyzed for FECP, FC, and FMPO.ResultsAll three fecal biomarkers were elevated in patients compared with controls (P = 0.000). Significant differences were found between inactive UC and controls (P = 0.000). Cases with severe UC had significantly higher FECP levels than those with mild UC (p < 0.05), but there were no significant differences in FC and FMPO levels among disease severity groups. All three biomarkers showed positive correlation with Ulcerative Colitis Activity Index (UCAI). The areas under the ROC curve of FECP, FC, and FMPO were 0.939, 0.783, and 0.785, respectively. Sensitivity and specificity of fecal biomarkers in assessing disease activity were FECP—88.46%, 89.47%; FC—80.77%, 68.42%; and FMPO—84.62%, 63.16%.ConclusionsAll three fecal biomarkers could be used as surrogate markers for assessing disease activity of UC, and FECP provided superior discrimination than FMPO and FC. Moreover, FECP could distinguish between mild disease and severe disease group.
Human Epididymis Protein 4: A Novel Biomarker for Lupus Nephritis and Chronic Kidney Disease in Systemic Lupus Erythematosus
Authors: Yang Zaixing , Zhang Zhiyu , Qin Baodong , Wu Ping , Zhong Renqian , Zhou Lin , Liang Yan 
Published: April 2016

BackgroundHuman epididymis protein 4 (HE4) is an available tumor biomarker for detecting ovarian cancer. However, it is unknown if serum HE4 could be a novel biomarker for diagnosis of lupus nephritis (LN) and chronic kidney disease (CKD) in patients with systemic lupus erythematosus (SLE).MethodsThis study enrolled 209 SLE patients, 75 patients with renal dysfunction without SLE and 32 healthy subjects. HE4 concentrations were analyzed by ELISA (enzyme‐linked immunosorbent assay; Fujirebio Diagnostics, Sweden). The receiver operating characteristic (ROC) curves were constructed to assess diagnostic accuracy of HE4 for LN or CKD in SLE.ResultsSerum HE4 level was significantly higher in SLE patients than that in healthy controls (P < 0.001), especially for those with LN or CKD. It was also higher in patients with renal dysfunction without SLE than healthy controls (P < 0.001), while there was no significant difference between these patients and those with SLE with CKD (P = 0.73). Multivariate analysis showed significant association between increased HE4 and LN or CKD after controlling for confounders. ROC curves showed the cutoff values were 150.1 pM (sensitivity, 76.8%; specificity, 91.1%) for the diagnosis of LN in SLE and 233.9 pM (sensitivity, 92.9%; specificity, 93.5%) for CKD in SLE.ConclusionsIncreased serum HE4 level is closely associated with the development of LN or CKD in SLE patients. Furthermore, it can be used as a novel and useful biomarker for diagnosis of LN or CKD.
Prediction of Infarct Transmurality From C‐Reactive Protein Level and Mean Platelet Volume in Patients With ST‐Elevation Myocardial Infarction: Comparison of the Predictive Values of Cardiac Enzymes
Authors: Kim DongHun , Choi Dong‐Hyun , Kim Bo‐Bae , Choi Seo‐Won , Park Keun Ho , Song Heesang 
Published: April 2016

BackgroundHigh C‐reactive protein (CRP) and mean platelet volume (MPV) levels are associated with poor prognosis in patients with ST‐segment elevation myocardial infarction (STEMI). The aim of this study was to evaluate the relationship between CRP level or MPV and infarct transmurality in patients with STEMI.MethodsWe retrospectively reviewed CRP level, MPV, and infarct transmurality in 112 STEMI patients who were assessed with contrast‐enhanced cardiac magnetic resonance imaging.ResultsWhen the cut‐off peak CRP level and MPV were set at 2.35 mg/dl and 7.3 fl using receiver operating characteristic curves analysis, the sensitivity was 67.3/69.2% and specificity was 76.7/76.7% for differentiating between the groups with and those without transmural involvement. Peak CRP level, MPV, peak creatine kinase‐MB (CK‐MB) level, and peak high‐sensitivity cardiac troponin T (hs‐cTnT) level had comparable predictive values for transmural involvement (area under the curve, 0.749, 0.761, 0.680, and 0.696, respectively). High peak CRP level and MPV were independent predictors of transmural involvement after adjusting for the peak CK‐MB level, peak hs‐cTnT level, baseline thrombolysis in myocardial infarction flow grade, and left ventricular ejection fraction (odds ratio: 5.16/5.42, 95% confidence interval: 1.84–14.50/2.03–14.47, P = 0.002/0.001, respectively) in the logistic regression analysis.ConclusionThe results of this study show that peak CRP level and MPV are predictive markers for transmural involvement. Their predictive power for transmural involvement is independent of and comparable to that of peak CK‐MB and hs‐cTnT levels.
Juvenile recurrent respiratory papillomatosis: 10‐year audit and Australian prevalence estimates
Authors: Novakovic Daniel , Cheng Alan T. L. , Baguley Katherine , Walker Paul , Harrison Henley , Soma Marlene , Malloy Michael , Brotherton Julia M. L. 
Published: April 2016

Objectives/HypothesisTo estimate the prevalence of juvenile onset recurrent respiratory papillomatosis (RRP) in Australia, describe its epidemiological profile, and assess the positive predictive value of International Classification of Disease, 10th revision (ICD‐10) code D14.1 (benign neoplasm of larynx) in children for hospitalization due to RRP.Study DesignRetrospective case series.MethodsRetrospective case review undertaken at the three tertiary pediatric hospitals in New South Wales (Australia's largest state), by reviewing medical records of patients aged 0 to 16 years admitted during 2000–2009 containing the ICD‐10 Australian modification code D14.1 or other possible disease (D14.2–4, D14.3, D14.4) and RRP‐related procedure codes. For RRP diagnoses, we recorded treatment dates, length of stay, extent of disease, and surgical and adjuvant treatments. The positive predictive value (PPV) of code D14.1 and median number of hospitalizations per year were applied to national hospital separations data from 2000/2001 to 2012/2013 to estimate disease prevalence.ResultsWe identified 30 cases of RRP using code D14.1, which had a PPV of 98.1%, with no further cases identified using other codes. Fifty‐seven percent of cases were female, median age of onset was 36 months, and median treatment duration was 36 months (mean = 40 months, range = 1–118). There was one patient death. Between 2000 and 2013, the estimated national prevalence rate was 0.81 per 100,000 aged < 15 years, peaking at age 5 to 9 years (1.1 per 100,000).ConclusionsRRP prevalence can be monitored after human papillomavirus vaccination programs using routine hospital data.Level of Evidence4 Laryngoscope, 126:2827–2832, 2016
Bioactive, Elastic, and Biodegradable Emulsion Electrospun DegraPol Tube Delivering PDGF‐BB for Tendon Rupture Repair
Authors: Evrova Olivera , Houska Joanna , Welti Manfred , Bonavoglia Eliana , Calcagni Maurizio , Giovanoli Pietro , Vogel Viola , Buschmann Johanna 
Published: April 2016

Healing of tendon ruptures represents a major challenge in musculoskeletal injuries and combinations of biomaterials with biological factors are suggested as viable option for improved healing. The standard approach of repair by conventional suture leads to incomplete healing or rerupture. Here, a new elastic type of DegraPol® (DP), a polyester urethane, is explored as a delivery device for platelet‐derived growth factor—BB (PDGF‐BB) to promote tendon healing. Using emulsion electrospinning as an easy method for incorporation of biomolecules within polymers, DegraPol® supports loading and release of PDGF‐BB. Morphological, mechanical and delivery device properties of the bioactive DP scaffolds, as well as differences arising due to different electrospinning parameters are studied. Emulsion electrospun DP scaffolds result in thinner fibers than pure DP scaffolds and experience decreased strain at break [%], but high enough for successful surgeon handling. PDGF‐BB is released in a sustained manner from emulsion electrospun DP, but not completely, with still large amount of it being inside the polymeric fibers after 30 d. In vitro studies show that the bioactive scaffolds promote tenocyte proliferation in serum free and serum+ conditions, demonstrating the potential of this surgeon‐friendly bioactive delivery device to be used for tendon repair.
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Virtual Screening of Receptor Sites for Molecularly Imprinted Polymers
Authors: Bates Ferdia , Cela‐Pérez María Concepción , Karim Kal , Piletsky Sergey , López‐Vilariño José Manuel 
Published: April 2016

Molecularly Imprinted Polymers (MIPs) are highly advantageous in the field of analytical chemistry. However, interference from secondary molecules can also impede capture of a target by a MIP receptor. This greatly complicates the design process and often requires extensive laboratory screening which is time consuming, costly, and creates substantial waste products. Herein, is presented a new technique for screening of “virtually imprinted receptors” for rebinding of the molecular template as well as secondary structures, correlating the virtual predictions with experimentally acquired data in three case studies. This novel technique is particularly applicable to the evaluation and prediction of MIP receptor specificity and efficiency in complex aqueous systems.
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Comparison of Reductive Ligation‐Based Detection Strategies for Nitroxyl (HNO) and S‐Nitrosothiols
Authors: Miao Zhengrui , King S. Bruce 
Published: April 2016

AbstractInvited for this month's cover picture is the group of Prof. S. Bruce King at the Department of Chemistry of Wake Forest University. The cover picture shows a prefluorescent phosphine‐based probe reacting with nitroxyl (HNO) and S‐nitrosothiol (RSNO), nitrogen oxide‐derived biological signals. Both species react with the prefluorescent probe, but only the product from the HNO reaction can complete a further chemical ligation pathway that results in fluorescence, indicating the presence of HNO. The product of the probe with RSNO does not complete this ligation and does not generate a fluorescent species. These phosphine‐based probes thus demonstrate a selectivity for HNO over RSNO based on their chemical reactivity and can be used in biological systems to differentiate these species. For more details, see the Communication on p. 110 ff. Read the full text of the article at 10.1002/open.201500200
Do School Report Cards Produce Accountability Through the Ballot Box?
Authors: Kogan Vladimir , Lavertu Stéphane , Peskowitz Zachary 
Published: April 2016

AbstractPublic education has been transformed by the widespread adoption of accountability systems that involve the dissemination of school district performance information. Using data from Ohio, we examine if elections serve as one channel through which these accountability systems might lead to improvements in educational quality. We find little evidence that poor performance on widely disseminated state and federal indicators has an impact on school board turnover, the vote share of sitting school board members, or superintendent tenure, suggesting that the dissemination of district performance information puts little (if any) electoral pressure on elected officials to improve student achievement.
The effect of diamine length on the direct solid state polycondensation of semi‐aromatic nylon salts
Authors: Papaspyrides C. D. , Porfyris A. D. , Rulkens R. , Grolman E. , Kolkman A. J. 
Published: April 2016

ABSTRACTIn the current paper, a comparative study on the direct solid state polycondensation (DSSP) reaction of different terephthalate based semi‐aromatic salts (XT salts, X = 4–18) in the TGA micro‐reactor is reported. High purity XT salts were prepared in solution and were used as starting materials for DSSP. The reaction temperature (TDSSP) for each salt was suitably selected as 20 °C–30 °C below the melting point Tm of the respective salt. The PAXT products were characterized by TGA/DSC, liquid 1H‐NMR, and SEM. In the DSSP of XT salts, some diamine is always lost to the gas phase and as a consequence, the attainable molecular weight of the polymer formed gets limited by the unbalance of acid and amine end‐groups. The TGA curves show that as the diamine length increases and its volatility decreases, higher molecular weights are obtained. SEM pictures of the products reveal true solid character during the polymerization reaction up to and including PA10T, whereas PA5T, PA12T, and PA18T reveal stickiness and agglomeration during reaction. A possible mechanism explaining such behaviour is also provided. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 2493–2506