bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dosimetric and radiobiological comparison of Cyberknife and Tomotherapy in stereotactic body radiotherapy for localized prostate cancer
Authors: Chen Chun-You , Lee Liang-Ming , Yu Hsiao-Wei , Lee Steve P. , Lee Hsin-Lun , Lin Yung-Wei , Wen Yu-Ching , Chen Yi-Ju , Chen Chiu-Ping , Tsai Jo-Ting 
Published: January 2017

BACKGROUND AND PURPOSE: As recent studies have suggested relatively low α/β for prostate cancer, the interest in hypofractionated stereotactic body radiotherapy (SBRT) for prostate cancer is rising. The aim of this study is to compare dosimetric results of Cyberknife (CK) with Tomotherapy (HT) in SBRT for localized prostate cancer. Furthermore, the radiobiologic consequences of heterogeneous dose distribution are also analyzed. MATERIAL AND METHOD: A total of 12 cases of localized prostate cancer previously treated with SBRT were collected. Treatments had been planned and delivered using CK. Then HT plans were generated for comparison afterwards. The prescribed dose was 37.5Gy in 5 fractions. Dosimetric indices for target volumes and organs at risk (OAR) were compared. For radiobiological evaluation, generalized equivalent uniform dose (gEUD) and normal tissue complication probability (NTCP) were calculated and compared. RESULT: Both CK and HT achieved target coverage while meeting OAR constraints adequately. HT plans resulted in better dose homogeneity (Homogeneity index: 1.04±0.01 vs. 1.21±0.01; p = 0.0022), target coverage (97.74±0.86% vs. 96.56±1.17%; p = 0.0076) and conformity (new vonformity index: 1.16±0.05 vs. 1.21±0.04; p = 0.0096). HT was shown to predict lower late rectal toxicity as compared to CK. Integral dose to body was also significantly lower in HT plans (46.59±6.44 Gy’L vs 57.05±11.68 Gy’L; p = 0.0029). CONCLUSION: Based on physical dosimetry and radiobiologic considerations, HT may have advantages over CK, specifically in rectal sparing which could translate into clinical benefit of decreased late toxicities.
Teaching–Learning Experience Regarding Skill in Using Inhalers: Medical Students Teaching Nursing Students
Authors: Ireland Catherine G. , Pigott Ellen M. , Tolley Elizabeth A. , Self Timothy H. 
Published: January 2017

Background:
Teaching–learning experience involving more than one health care discipline is a topic of great interest in the health sciences. Few such experiences are known in which medical students taught nursing students a clinical skill.

Method:
The authors evaluated the effect of fourth-year medical students teaching the correct use of a metered-dose inhaler (MDI) to bachelor of science nursing (BSN) students. An fourth-year medical student investigator taught BSN students the correct use of an MDI in individual, private educational sessions, approximately 10 minutes in length, in a large health sciences center. BSN students were scored in use of MDI preeducation and posteducation. Instruction included both discussion and demonstration by the M4S.

Results:

Among 20 BSN students, posteducation scores were markedly improved for total steps (
p
< .0001), and six of nine individual steps for MDI use.

Conclusion:

Brief teaching–learning sessions are effective in teaching nursing students the correct use of MDI. [
J Nurs Educ.
2017;56(2):120–122.]
A New Uzawa-Type Iteration Method for Non-Hermitian Saddle-Point Problems
Authors: Dou Yan , Yang Ai-Li , Wu Yu-Jiang 
Published: January 2017

AbstractBased on a preconditioned shift-splitting of the (1,1)-block of non-Hermitian saddle-point matrix and the Uzawa iteration method, we establish a new Uzawa-type iteration method. The convergence properties of this iteration method are analyzed. In addition, based on this iteration method, a preconditioner is proposed. The spectral properties of the preconditioned saddle-point matrix are also analyzed. Numerical results are presented to verify the robustness and the efficiency of the new iteration method and the preconditioner.
My Vocational Situation (MVS): Case Example and Psychometric Review
Authors: Nitsch Kristian P. , Pedersen Jessica , Miliotto Alexandra , Petersen Brett , Robbins Samantha , Garcia Ana , Hoisington Molly Ansel , The Kimberly J. , Smiley Jill , Janikowski Timothy 
Published: January 2017

Abstract
This case report provides an overview of the psychometric properties and clinical utility of the My Vocational Situation (MVS) instrument. The accompanying hypothetical case description illustrates how clinicians could use the MVS to evaluate vocational preferences and outcomes and how the MVS can be used to inform treatment planning and rehabilitation decision making. The information contained in this report is intended to familiarize clinicians with the administration and scoring of the MVS, the psychometric information necessary to interpret results obtained from the MVS, and how the results could be used to provide comprehensive, patient-centered care. It is important to note that the information provided represents only a sample of the available research literature on the MVS.
OXIDATIVE STRESS RELAXATION OF NATURAL RUBBER GUM VULCANIZATES CONTAINING VARIOUS ANTIOXIDANTS. I: EFFECT OF SAMPLE THICKNESS
Authors: Zhao Junling , Hamed G. R. 
Published: January 2017

ABSTRACT
Conventional sulfur-vulcanized natural rubber gums containing various antioxidants have been subjected to oxidative stress relaxation at 72 °C and 25% strain. Oxidation is diffusion controlled, even for samples as thin as 0.15 mm. Assuming that the rate of chain scission is proportional to the rate of oxygen absorption, which previously has been shown to depend on the square root of the oxygen concentration, an equation is derived predicting that stress decay is proportional to aging time to the three-quarters power. Moreover, slopes of these plots are predicted to depend inversely on thickness. Experimental results are in reasonable accord with these predictions.
Caracterización del programa de acompañamiento pedagógico en el marco del Plan Nacional de Desarrollo Humano (PNUD) de Nicaragua
Authors: Báez Osegueda José Ramón Ramón , Benavidez Briones Wendy Yahoska , Gómez Calero Génesis Yamalí , González Olivas Noé Antonio , Castillo Herrera Beverly 
Published: January 2017

Abordar los principales aspectos que han determinado el actual atraso latinoamericano, implica reflexionar sobre su trayectoria histórica. El “desarrollo”, caracterizado por la perspectiva de la dominación que ha sufrido la región latinoamericana a favor de las industrias y transnacionales del mundo desarrollado, se convierte cada vez más en sujeto de análisis tanto para las instituciones académicas como para los gobernantes de los países del sur, puesto que, las naciones consideradas “subdesarrolladas”, requieren urgentemente de estudios sistemáticos y soluciones transformadoras de este fenómeno devastador. El Gobierno de Reconciliación y Unidad Nacional de Nicaragua por medio del Plan Nacional de Desarrollo Humano bajo su lineamiento de restitución de los derechos y la reducción de la desigualdad y la pobreza ha creado mecanismos eficientes que han contribuido al desarrollo integral del país, con la implementación de políticas públicas que benefician a todos los sectores productivos de nuestra nación, es notable el dinamismo social-productivo del país con los programas y proyectos impulsados, uno de ellos es el Acompañamiento Pedagógico que es dirigido a través del Ministerio de Educación, tiene como fin Fortalecer el protagonismo de las y los docentes líderes del cambio y la innovación del proceso educativo, mediante buenas prácticas y estrategias de evaluación del aprendizaje asegurando la aplicación eficaz de los pasos metodológicos para el Aprendizaje de la Lectura, escritura y Matemática, en un ambiente sano, saludable y seguro, que propicie su tránsito exitoso en el Sistema Educativo.
The Music of Thinking: A Literary Experiment with the Great Themes of Philosophy
Authors: Seel Martin 
Published: January 2017

In his book Theorien (Frankfurt am Main: S. Fischer, 2009) Martin Seel presents a philosophical and literary experiment in which he desists from introducing a single grand theory in favour of offering a number of smaller theories. In an aphoristic manner these personal and poetic observations are linked to rigorous reflections on the classical themes of human selfunderstanding: happiness and morality, failure and beauty, sickness and death, sense and understanding, knowledge and freedom, religion and music. Staying clear of disciplinary formations, the author shuffles the cards of epistemology, ethics and aesthetics in order to address philosophy as a whole without extinguishing its fire within the confines of a systematic edifice. This collection of shortcuts can be read from beginning to end, or backwards, or starting in the middle; as a reflection on thinking; a play with the voices of passion; a variation on foundations and pitfalls of action; a defence of the indeterminate in all that is determinate; as a fragment of a prosaic confession. These heterogeneous gestures unfold an improvised text that tracks the uncertainties of life and of writing. This text is an excerpt from the book, published in Die Zeit no. 37, September, 2009.
Receiving Newman. Formalism, Minimalism, and their Philosophical Preconditions
Authors: Dahl Espen 
Published: January 2017

Despite the divide between American formalism and theoreticians of minimalism, Barnett Newman’s art received great acclaim from both schools of thought. Attempting to unearth the philosophical preconditions of this strange constellation, this article argues that the closeness between minimalism and formalism is due to their mutual reliance upon phenomenology and ordinary language philosophy. However, their proximity also conveys their distance, since they imply different interpretations and applications of the philosophical schools in question. Such theoretical differences shed light on Newman’s paintings: both minimalism and formalism are right in their accounts – yet not exclusively so. What arguably makes up the distinctive fascination of Newman’s paintings is their incessant oscillation between empty physicality and powerful meaning.
Aesthetic Reasoning: A Hermeneutic Approach
Authors: Davey Nicholas 
Published: January 2017

This essay considers the foundations of reasonable evaluation in the arts. These we argue concern the relations that constitute (1) our experience of art, and (2) the ontology of the art work itself. The being of the artwork, the experience and the interpretation of it all involve over-lapping modes of part–whole relations. The experience of meaningfulness is not an experience of a singular object or framework of meaning as closed and complete but an experience of relational meaning whereby exposure to one set of meaningful relations transforms another in an on-going and open manner. This suggests that the experience of art itself provides the norms for reasonableness of evaluation. These norms are not rules in the sense of offering a method. They are characteristic of the features of an experience of meaningfulness itself. The essay suggests that the reasonableness of a response to a work can be considered in terms of (1) its appropriacy relative to the context of its own horizon and the horizon surrounding the production of the work; (2) its plausibility, that is, its internal coherence and consistency as a reading; (3) whether the structure of the response is consistent with, supplements, or expands the intelligible content of the work; and (4) whether it gives a sense of the latent possibilities still held within a work and intimates where the movement of a work’s subject-matter might
Babel and Jericho: Architectural Myths for Technological and Psychological Catastrophes
Authors: De Kerckhove Derrick 
Published: January 2017

We live in mythical times when the consequences of human social behavior find an expression in large events that mark the century, from the Fall of the Berlin Wall, to that of the towers of the World Trade Centre. Our public figures such as Putin, Erdogan, Bush, both Clintons or Trump are tragic figures occupying the world stage and deciding its destiny. We can seek a pattern in ancient myths to tell modern
stories. This paper takes the architectural approach regarding the building or the tearing down of walls, specifically those of Babel, Jericho and the Berlin Wall in order to assess their deeper meaning in terms of the larger picture.
The prognostic value of tumor length to resectable esophageal squamous cell carcinoma: a retrospective study
Authors: Zhang Xiangwei , Wang Yang , Li Cheng , Helmersson Jing , Jiang Yuanzhu , Ma Guoyuan , Wang Guanghui , Dong Wei , Sang Shaowei , Du Jiajun 
Published: January 2017

Background
The current TNM classification system does not consider tumor length for patients with esophageal carcinoma (EC). This study explored the effect of tumor length, in addition to tumor depth and lymph node involvement, on survival in patients with esophageal squamous cell carcinoma (ESCC).

Methods
A total of 498 ESCC patients who underwent surgical resection as the primary treatment were selected in the retrospective study. Pathological details were collected, which included tumor type, TNM stage, differentiation. Other collected information were: the types of esophageal resection, ABO blood group, family history and demographic and lifestyle factors. A time-dependent receiver operating characteristic (ROC) curve and a regression tree for survival were used to identify the cut-off point of tumor length, which was 3 cm. Univariate and multivariate Cox proportional hazard regression models were used to identify the prognostic factors to ESCC.

Results & Discussion
The 1-, 3-, 5-year overall survival rates were found to be 82.5%, 55.6%, and 35.1%, respectively. Patients who had larger tumor length (>3 cm) had a higher risk for death than the rest patients. From the univariate Cox proportional hazards regression model, the overall survival rate was significantly influenced by the depth of the tumor and lymph node involvement (either as dummy or continuous variables), Sex, and tumor length. Using these four variables in the multivariate Cox proportional hazard regression model, we found that the overall survival was significantly influenced by all variables except Sex. Therefore, in addition to the depth of the tumor and lymph node involvement (as either dummy or continuous variables), the tumor length is also an independent prognostic factor for ESCC. The overall survival rate was higher in a group with smaller tumor length (≤3 cm) than those patients with larger tumor length (>3 cm), no matter what the tumor stage was.

Conclusion
The tumor length was found to be an important prognostic factor for ESCC patients without receiving neoadjuvant therapy. The modification of EC staging system may consider tumor length to better predict ESCC survival and identify higher risk patients for postoperative therapy.
Oficinas de aprimoramento da comunicação oral em adultos: um estudo de caso
Authors: Neves Paloma Cristina Rodeiro , Falcão Ana Regina Graner , Toralles Maria Betânia Pereira 
Published: January 2017

<p><strong>Objetivo</strong>: Relatar a percepção de um sujeito a respeito das oficinas de aprimoramento da comunicação oral em adultos inscritos na lista de espera da Clínica-Escola Professor Jurandy Gomes de Aragão, da Universidade do Estado da Bahia, com alguma dificuldade na comunicação oral. <strong>Metodologia:</strong> Estudo de caso de caráter qualitativo descritivo e corte transversal, realizado por meio de uma entrevista semiestruturada, dividida em duas etapas. A primeira contendo itens relacionados aos dados de identificação que possam levantar o perfil do sujeito da pesquisa e a segunda, questões norteadoras referentes ao objeto de estudo. A partir do relato obtido, foi feita a análise de Bardin (Análise do Conteúdo). Posteriormente as fases de análise, foi possível organizar categorias de acordo com a frequência de aparecimento no depoimento. <strong>Resultados: </strong>Diante das releituras e análises da narrativa da entrevistada, verificamos que a comunicação efetiva, a empatia e o trabalho em grupo foram fatores presentes durante as Oficinas e decisivos para a eficácia do atendimento fonoaudiológico diferenciado.<strong> Conclusão:</strong> Ficou evidente que a abordagem grupal na Fonoaudiologia é benéfica, facilitando o aprimoramento da comunicação oral.No entanto, considerando-se que a atuação fonoaudiológica em grupo é ainda uma estratégia terapêutica pouco utilizada, novas pesquisas e estudos na área devem ser incentivados.</p><p> </p>
Prevalência de traumas infantis: uma investigação com adolescentes de uma escola pública em Salvador, Brasil
Authors: Vasconcelos Nina Maia de , Botelho Ana Cristina Batista , Oliveira Irismar Reis de 
Published: January 2017

<p>Introdução: eventos traumáticos na infância podem afetar significativamente a vida do indivíduo, aumentando a probabilidade de desenvolvimento de transtornos mentais no futuro. Objetivo: Verificar a prevalência de traumas vividos por adolescentes, alunos de uma escola pública de Salvador. Metodologia: estudo sobre a ocorrência de traumas sofridos na infância, utilizando o questionário QUESI em 274 adolescentes, alunos de escola pública, com idades entre 12 e 17 anos, no contexto de um ensaio clínico acerca da eficácia do Treinamento Cognitivo Processual em Grupo, para prevenção de transtornos de ansiedade e depressão em adolescentes. Resultados: 92,7% sofreram algum tipo de abuso na infância e 7,3% não sofreram nenhum tipo de abuso. Dentre os três tipos de abuso investigados, a prevalência do abuso emocional foi de 90,87%, a de abuso físico foi de 42,34% e a de abuso sexual, de 11,67%. Os abusos foram mais frequentes no sexo masculino do que no feminino. Conclusão: a investigação sobre traumas sofridos na infância possibilita uma melhor compreensão da etiologia dos transtornos psiquiátricos e ratifica a necessidade do desenvolvimento de políticas públicas de proteção às crianças e adolescentes.</p><p> </p>
A Concise Synthesis of Novel Aryl Pyrimidine C‐Nucleoside Analogs from Sugar Alkynes
Authors: Zhang Fuyi , Liang Yan , Li Jing , Gao Fei , Liu Hong , Zhao Yufen 
Published: January 2017

AbstractAryl‐ and amino‐substituted pyrimidine C‐nucleoside analogs have been synthesized in good to excellent yields by one‐pot coupling of terminal sugar alkynes, substituted benzoyl chlorides, and amidine salts. The reaction conditions are tolerant of various structurally complex sugars having sterically bulky groups, unprotected hydroxyl groups, and sensitive substituents. The sugar alkynes include structurally diverse pyranosides, acyclic glycosides, and furanosides. The substituted benzoyl chlorides bear electron‐withdrawing and ‐donating substituents with different steric hindrance. The amidine salts include acetamidine hydrochloride, benzamidine hydrochloride, and guanidine hydrochloride.
Synthesis of 1,8‐Anthracene–Ethenylene Cyclic Dimers and Related Compounds: Effects of Linkers on their Structures, Electronic Properties, and Dynamic Behavior
Authors: Inoue Masataka , Iwanaga Tetsuo , Toyota Shinji 
Published: January 2017

AbstractCyclic compounds consisting of two 10‐mesityl‐1,8‐anthracene units with trans‐ or cis‐ethenylene linkers and their ethynylene and ethylene analogs were synthesized by cross‐coupling reactions and catalytic hydrogenation reactions. The structures of the four compounds were investigated by X‐ray analysis and DFT calculations. The trans‐ethenylene and ethylene compounds had nonplanar stair‐like frameworks, whereas the cis‐ethenylene compound had a rigid folded framework. In the UV/Vis spectra, the absorption bands red‐shifted in the order of ethylene, cis‐ethenylene, trans‐ethenylene, and ethynylene compounds according to an increase in π‐conjugation. The fluorescence spectra showed that these compounds were emissive in solution as well as in the solid state. Dynamic processes involving the exchange between the two syn forms were observed for the trans‐ethenylene and ethylene compounds by variable temperature 1H NMR measurements. The effects of linkers on electronic properties and dynamic behavior are discussed on the basis of their molecular structures and molecular orbitals.
Beryllium‐Free β‐Rb2Al2B2O7 as a Possible Deep‐Ultraviolet Nonlinear Optical Material Replacement for KBe2BO3F2
Authors: Tran T. Thao , Koocher Nathan Z. , Rondinelli James M. , Halasyamani P. Shiv 
Published: January 2017

AbstractA new beryllium‐free deep‐ultraviolet (DUV) nonlinear optical (NLO) material, β‐Rb2Al2B2O7 (β‐RABO), has been synthesized and characterized. The chiral nonpolar acentric material shows second‐harmonic generation (SHG) activity at both 1064 and 532 nm with efficiencies of 2×KH2PO4 and 0.4×β‐BaB2O4, respectively, and exhibits a short absorption edge below 200 nm. β‐Rb2Al2B2O7 has a three‐dimensional structure of corner‐shared Al(BO3)3O polyhedra. The discovery of β‐RABO shows that through careful synthesis and characterization, replacement of KBe2BO3F2 (KBBF) by a Be‐free DUV NLO material is possible.
Induction of Strong and Tunable Circularly Polarized Luminescence of Nonchiral, Nonmetal, Low‐Molecular‐Weight Fluorophores Using Chiral Nanotemplates
Authors: Goto Taisei , Okazaki Yutaka , Ueki Masahiro , Kuwahara Yutaka , Takafuji Makoto , Oda Reiko , Ihara Hirotaka 
Published: January 2017

AbstractA new strategy is described for generating strong circularly polarized luminescence with highly tunable emission bands through chiral induction in nonchiral, totally organic, low‐molecular‐weight fluorescent dyes by chiral nanotemplate systems. Our approach allows the first systematic investigation to clarify the correlation between the circular dichroism and circularly polarized luminescence intensities. As a result, a dilute solution system with the highest circularly polarized luminescence intensity achieved to date and a dissymmetry factor of over 0.1 was identified.
A Stimuli‐Responsive Smart Lanthanide Nanocomposite for Multidimensional Optical Recording and Encryption
Authors: Li Xiang , Xie Yujie , Song Bo , Zhang Hao‐Li , Chen Hao , Cai Huijuan , Liu Weisheng , Tang Yu 
Published: January 2017

AbstractA stimuli‐responsive lanthanide‐based smart nanocomposite has been fabricated by supramolecular assembly and applied as an active material in multidimensional memory materials. Conjugation of the lanthanide complexes with carbon dots provides a stimuli response that is based on the modulation of the energy level of the ligand and affords microsecond‐to‐nanosecond fluorescence lifetimes, giving rise to intriguing memory performance in the spatial and temporal dimension. The present study points to a new direction for the future development of multidimensional memory materials based on inorganic–organic hybrid nanosystems.
Measuring Nanoscale Thermostability of Cell Membranes with Single Gold–Diamond Nanohybrids
Authors: Tsai Pei‐Chang , Epperla Chandra P. , Huang Jo‐Shan , Chen Oliver Y. , Wu Chih‐Che , Chang Huan‐Cheng 
Published: January 2017

AbstractMuch of the current understanding of thermal effects in biological systems is based on macroscopic measurements. There is little knowledge about the local thermostability or heat tolerance of subcellular components at the nanoscale. Herein, we show that gold nanorod–fluorescent nanodiamond (GNR‐FND) hybrids are useful as a combined nanoheater/nanothermometer in living cells. With the use of a 594 nm laser for both heating and probing, we measure the temperature changes by recording the spectral shifts of the zero‐phonon lines of negatively charged nitrogen‐vacancy centers in FNDs. The technique allows us to determine the rupture temperatures of individual membrane nanotubes in human embryonic kidney cells, as well as to generate high temperature gradients on the cell membrane for photoporation and optically controlled hyperthermia. Our results demonstrate a new paradigm for hyperthermia research and application.