bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: The in‐Bicyclo(4.4.4)‐1‐tetradecyl Cation (VI): A Stable Substance with a Three‐Center, Two‐Electron C‐H‐C Bond.
Authors: MCMURRY J. E. , LECTKA T. , HODGE C. N. 
Published: May 2016

AbstractCatalytic hydrogenation of the alkene (V) (H2, Pd‐C) yields the in,out‐bicyclo(4.4.4)tetradecane.
ChemInform Abstract: Imidolactones. Part 4. N‐(2‐Phenylethyl)hexahydroisochroman‐1‐imines.
Authors: MEISE W. , MIKA U. 
Published: May 2016

AbstractDepending on the reaction conditions, coupling of the 2‐phenylethylamines (II) with the cis‐isochromanone (I) gives the cis‐ (III) or the trans‐2‐hydroxyethylcyclohexanecarboxamides (IV) as the main products.
ChemInform Abstract: Activation of Reducing Agents. Sodium Hydride‐Containing Complex Reducing Agents. Part 32. NiCRAL′s as Very Efficient Agents in Promoting Cross‐Coupling of Aryl Halides.
Authors: LOURAK M. , VANDERESSE R. , FORT Y. , CAUBERE P. 
Published: May 2016

AbstractForty‐seven coupling reactions between aryl bromides such as (I) and aryl chlorides such as (II) are carried out with the NiCRA‐bpy reagent.
ChemInform Abstract: Preference for anti‐1,4‐Elimination of Hydrochloric Acid Promoted by Base in Systems with Non‐Cyclic C(1)‐C(2) Bonds.
Authors: OELWEGARD M. + , AHLBERG P. 
Published: May 2016

AbstractTreatment of the diastereomeric chloroethyldeuterioindenes (I) or (IV) with DABCO (1,4‐diazabicyclo(2.2.2)octane) results in 1,4‐elimination of HCl, producing the ethylideneindenes (I) and (III).
ChemInform Abstract: Diethylaminopropionamido(hydroxy)anthraquinones as Potential Anticancer Agents: Synthesis and Characterization.
Authors: ANTONELLO C. , URIARTE E. , PALUMBO M. 
Published: May 2016

AbstractThe 1‐amino‐4‐hydroxyanthraquinones (I) are coupled with 3‐chloropropionyl chloride (II), yielding the corresponding amides (III).
ChemInform Abstract: Synthesis of the Non‐K‐Region Arene Oxides and Tetrahydro Epoxides of Dibenz(a,h)anthracene.
Authors: PLATT K. L. , FRANK H. , OESCH F. 
Published: May 2016

AbstractThe title compounds (VIII) and (IX) are prepared starting from the ketone (III), for which an improved synthesis is described.
ChemInform Abstract: Synthesis and Structure of a New Chiral Oxaziridine from (3‐Oxo‐camphorsulfonyl)imine.
Authors: MELADINIS V. , HERRMANN R. , STEIGELMANN O. , MUELLER G. + 
Published: May 2016

AbstractOxidation of the camphor derivative (I) by magnesium monoperoxyphthalate affords the novel title compound (II) with an oxygen atom inserted in the cyclohexane moiety of (I).
ChemInform Abstract: Unsymmetrically Substituted Furoxans. Part 11. Methylfuroxancarbaldehydes.
Authors: FRUTTERO R. , FERRAROTTI B. , SERAFINO A. , DI STILO A. , GASCO A. 
Published: May 2016

AbstractThe structures of the title compounds (III) and (IV), their thermal equilibration and the kinetics of the conversion of (III) to (IV) are discussed.
ChemInform Abstract: Electrophilic Condensation of Silyl Ethers of Homopropargyl Alcohols with Aldehydes. Regioselective Synthesis of Dihydropyrans.
Authors: CHAN T.‐H. , ARYA P. 
Published: May 2016

AbstractThe homopropargylic alcohol (I) reacts with the aldehydes (II) in the presence of AlCl3 to give mixtures of the hydroxy enones (III) ‐ (V).
ChemInform Abstract: Synthesis of Pyrano(4,3‐b)indoles as Conformationally Restricted Analogues of the Serotonin Antagonist ICS 205‐930 and as Precursors to 2‐Vinylindoles.
Authors: MACOR J. E. , RYAN K. , NEWMAN M. E. 
Published: May 2016

AbstractThe ethyl indole‐3‐carboxylate (I) is methylated and subsequently coupled with the ketones and aldehydes (III) to form the lactones (IV), together with the 2‐vinylindole‐3‐carboxylic acids (V).
ChemInform Abstract: Superoxide Anion Radical (O2·‐)‐Mediated Base‐Catalyzed Autoxidation of α‐Keto Enols.
Authors: FRIMER A. A. , GILINSKY‐SHARON P. , ALJADEFF G. , ROSENTAL Z. 
Published: May 2016

AbstractAutoxidation of the hydroxycyclohexadienones (I) in the presence of the superoxide anion radical, generated from KO2 and a crown ether, produces the lactols (II).
ChemInform Abstract: An Unexpected Aromatic SN2′ Substitution of a 4‐Bromobenzopyran.
Authors: HOUGE‐FRYDRYCH C. S. V. , MARSH A. , PINTO I. L. 
Published: May 2016

AbstractThe 4‐bromodihydrobenzopyran (I) reacts with the carboxamides (II) in the presence of a base to give the 5‐substituted dihydrobenzopyrans (III).
ChemInform Abstract: Trifluorothioacetaldehyde.
Authors: SCHULER B. , SUNDERMEYER W. 
Published: May 2016

AbstractTrifluoroacetaldehyde hydrate (I) reacts with 1,2‐ethanedithiol (II) to give the dithioacetal (III) which is selectively oxidized, yielding the dithiolane 1,1‐dioxide (IV).
ChemInform Abstract: Formation of Isopropylidenepyridoxines. A Convenient Method for the Preparation of 2,2,8‐Trimethyl‐4H‐1,3‐dioxino(4,5‐c)pyridin‐5‐ylmethanol from Pyridoxine Hydrochloride.
Authors: WU Y. , AHLBERG P. 
Published: May 2016

AbstractAn improved and more reliable method of preparation of the title compound (III) is reported.
ChemInform Abstract: Diisophorone and Related Compounds. Part 22. 8,11a‐Methanocycloocta(d,e)quinazolines: Diisophoranes Incorporating the Pyrimidine Ring System.
Authors: KURZER F. , LANGER S. S. 
Published: May 2016

AbstractWhile corresponding systems incorporating a dioxepane, pyridine, diazepine or thiazine moiety are known, the title compounds (IV)/(V) and the oxazine analogue (VIII) represent novel ring systems.
ChemInform Abstract: Synthesis of Fused Polyazapolycyclic Compounds Through Condensation of Diaminoalkanes with Carbonyl Compounds.
Authors: BLACK D. STC. , CRAIG D. C. , GIITSIDIS O. , READ R. W. , SALEK A. , SEFTON M. A. 
Published: May 2016

AbstractThe diaminopropanes (I) react with glyoxal (II) to give the bis(hexahydropyrimidines) (III) which are converted into the tetranitro derivatives (V) upon treatment with nitric acid (IV).
ChemInform Abstract: Syntheses of 1,3,6,8,10,11,14‐Heptaazapentaphene‐2,4,7,9(14H,3H,8H,11H)‐tetrones (Angular Mixed Flavins), 1,3,5,6,8,10,11,14‐Octaazapentaphene‐2,4,7,9(14H,3H,8H,11H)‐tetrones (Angular Doubled Flavins), and Their Related Compounds.
Authors: YONEDA F. , KOGA M. , TANAKA K. , YANO Y. 
Published: May 2016

AbstractThe title compounds (VI) and (VIII) and other related polyazapolycyclic compounds are prepared via the Vilsmeier route.
ChemInform Abstract: The Thiophene Analogue of Porphyrin: Tetrathiaporphyrin Dication (IVb).
Authors: VOGEL E. , ROEHRIG P. + , SICKEN M. , KNIPP B. , HERRMANN A. , POHL M. , SCHMICKLER H. , LEX J. 
Published: May 2016

AbstractFurfuryl alcohol (I) is tranformed into the dication (IVb) (having space group P1 with Z=2) via a remarkably straightforward sulfur/oxygen exchange in (IIIa) to give (IIIb) (P21/c with Z=2).
ChemInform Abstract: Macrolactonization of β‐Hydroxy Acids. Crystal Structures of the Pentolide and the Hexolide from (R)‐3‐Hydroxybutanoic Acid. Molecular Modeling Studies of the Tetrolide.
Authors: SEEBACH D. , BRAENDLI U. + , MUELLER H.‐M. + , DOBLER M. , EGLI M. , PRZYBYLSKI M. , SCHNEIDER K. 
Published: May 2016

AbstractUnder Yamaguchi's macrolactonization conditions, the oligolides (IIIa)‐(IIIc) and higher oligomers are formed from (R)‐(I); while there is hardly any effect of concentration, change of temp. has a pronounced effect of product ratios except for (IIIb) which is constantly ca. 35% of the product mixture.
ChemInform Abstract: Synthesis of Halothiophene S,C‐Ylides and the Corresponding 1,4‐Oxathiocines.
Authors: METH‐COHN O. , VUORINEN E. , MODRO T. A. 
Published: May 2016

AbstractRhodium(II) acetate‐catalyzed reaction of the thiophenes (I) with the diazo‐β‐dicarbonyl compounds (II) produces the ylides (III) at room temperature.
ChemInform Abstract: Transformation of Diethyl Phosphite in the Presence of Mn2(CO)10.
Authors: MOSKALENKO M. A. , KARDANOV N. A. , TERENT'EV A. B. , GODOVIKOV N. N. 
Published: May 2016

AbstractHeating of diethyl phosphite (I) with methyl bromoacetate (II) in the presence of dimanganese decacarbonyl gives triethyl phosphate (III), diethyl ethylphosphonate (IV), methyl acetate (V), and dimethyl succinate (VI).
ChemInform Abstract: Metal Complexes of Functional Isocyanides. Part 19. Vinyl and Chlorovinyl Isocyanide Complexes.
Authors: FEHLHAMMER W. P. , BECK G. 
Published: May 2016

AbstractThe chlorovinyl isocyanide‐Cr complexes (II), (IV), and (V) are synthesized by elimination of chloride from the tetra‐ and trichloroethyl isocyanide‐Cr complexes (I) and (III) according to the scheme.
ChemInform Abstract: Reactions of an Imidoyl Halide with Manganese Carbonyl Complexes.
Authors: MOTZ P. L. , ALEXANDER J. J. , CAMPANA C. F. 
Published: May 2016

AbstractThe carbonylate anion of (II) reacts with (I) to give the product (III) (space group P1, Z=2) which results from head‐to‐tail coupling of two imidoyl groups and reduction of the internal C=N bond.
ChemInform Abstract: Synthesis and Structure of a New Type of Chiral Organoiron and Organoruthenium Complexes.
Authors: ADAMS C. M. , HAFNER A. , KOLLER M. , MARCUZZI A. , PREWO R. , SOLANA I. , VINCENT B. , VON PHILIPSBORN W. 
Published: May 2016

AbstractThe synthesis of 36 complexes of type (III), three of type (IX) and five of type (XII) by thermal, selective CO ligand displacement in the corresponding tricarbonyl precursors is described as demonstrated for the examples given in the scheme.
ChemInform Abstract: Redox Regulation in Ruthenium(II) Complexes of 2,6‐Bis(N‐pyrazolyl)pyridine Ligands: Synthetically Versatile Analogues of 2,2′:6′,2′′‐Terpyridine.
Authors: JAMESON D. L. , BLAHO J. K. , KRUGER K. T. , GOLDSBY K. A. 
Published: May 2016

AbstractA new family of planar tridentate ligands (III) and (IV), which are structural analogues to terpyridine with the added feature that the ligand superstructure can be conveniently varied, are prepared according to the scheme.
ChemInform Abstract: Oligomeric Dicyanobis(polypyridine)ruthenium(II) Complexes. Synthesis and Spectroscopic and Photophysical Properties.
Authors: BIGNOZZI C. A. , ROFFIA S. , CHIORBOLI C. , DAVILA J. , INDELLI M. T. , SCANDOLA F. 
Published: May 2016

AbstractThe synthesis of the complexes (III) and (V) are carried out with a 10‐fold excess of (II) to minimize the formation of polymeric species.
ChemInform Abstract: Vinylidene Transition‐Metal Complexes. Part 9. Synthesis and Reactivity of Vinylidene Rhodium Complexes Containing C=CHtBu and C=CHCO2Me as Ligands.
Authors: WERNER H. , BREKAU U. 
Published: May 2016

AbstractThe square‐planar alkyne Rh complexes (I) bearing at least one electron withdrawing substituent at the C≡C triple bond are prepared from (III) and the alkynes (II).
ChemInform Abstract: Building Units of Oligosaccharides. Part 44. Synthesis of KDO‐Containing Tri‐ and Tetrasaccharide Sequences of the Inner Core and Lipoid A Region of Lipopolysaccharides.
Authors: PAULSEN H. , KROGMANN C. 
Published: May 2016

AbstractThe glycosyl acceptor (I), which contains two glycosidically β(1 → 6) linked 2‐amino‐2‐deoxy‐D‐glucose residues, is used for the synthesis of the title compounds (IIa) and (IIb).
ChemInform Abstract: A Rapid Entry to Carbocycles from Carbohydrates via Intramolecular Nitrone Cycloaddition.
Authors: SHING T. K. M. , ELSLEY D. A. , GILLHOULEY J. G. 
Published: May 2016

AbstractThe acetonide (I), obtained from D‐ribose, is coupled with vinylmagnesium bromide (II) and then oxidized to give the vinyllactol (IV).
ChemInform Abstract: Nucleotides. Part 32. Synthesis of 2′‐5′ Connected Oligonucleotides. Prodrugs for Antiviral and Antitumoral Nucleosides.
Authors: HERDEWIJN P. , CHARUBALA R. , DE CLERCQ E. , PFLEIDERER W. 
Published: May 2016

AbstractCoupling of cytotoxically and antivirally active nucleosides with diadenylates by the phosphotriester approach leads to the title prodrugs, e.g. (I) and (II).
ChemInform Abstract: Enantiomerically Pure 7‐Oxabicyclo(2.2.1)hept‐5‐en‐2‐yl Derivatives (“Naked Sugars”) as Synthetic Intermediates. Part 8. Total Synthesis of 2‐(β‐D‐Ribofuranosyl)thiazole‐4‐carboxamide (Tiazofurin) and of Precursors of ribo‐C‐Nucleosides.
Authors: BIMWALA R. M. , VOGEL P. 
Published: May 2016

AbstractPrecursors of ribo‐C‐nucleosides, e.g. (V) and (VII), and tiazofurin (XI) are synthesized starting from the 7‐oxanorbornane derivative (I).
ChemInform Abstract: Preparation of 1‐(2,3‐Dideoxy‐β‐D‐glycero‐pent‐2‐enofuranosyl)thymine (d4T) and 2′,3′‐Dideoxyadenosine (ddA): General Methods for the Synthesis of 2′,3′‐Olefinic and 2′,3′‐Dideoxy Nucleoside Analogues Active Against HIV.
Authors: MANSURI M. M. , STARRETT J. E. JUN. , WOS J. A. , TORTOLANI D. R. , BRODFUEHRER P. R. , HOWELL H. G. , MARTIN J. C. 
Published: May 2016

AbstractThree different synthetic routes for the production of the 2',3'‐unsaturated nucleoside (Va) are reported.
ChemInform Abstract: Synthesis of (+)‐Aspicilin Using Building Blocks from Renewable Resources.
Authors: QUINKERT G. , FERNHOLZ E. , ECKES P. , NEUMANN D. , DUERNER G. + 
Published: May 2016

AbstractThe 18‐membered lichen macrolide (I) is prepared in 15 steps with an overall yield of 13% from D‐mannose.
ChemInform Abstract: New Cell Growth‐Inhibitory Cyclohexadienone Derivatives (I)‐(III) from Hypericum calycinum L.
Authors: DECOSTERD L. A. , STOECKLI‐EVANS H. , CHAPUIS J.‐C. , SORDAT B. , HOSTETTMANN K. 
Published: May 2016

AbstractThe extract of the aerial parts of H. calycinum exhibits in vitro growth‐inhibitory activity against the Co‐115 human colon carcinoma cell line.
ChemInform Abstract: Ab initio Studies of Molecular Structures and Energetics. Part 4. Hexacoordinated NF‐ 6 and CF2‐ 6 Anions.
Authors: EWIG C. S. , VAN WAZER J. R. 
Published: May 2016

AbstractThe energies, equilibrium molecular structures, and vibrational frequencies of the title anions are computed employing the second‐order perturbation approximation (MP2) for the energy.
ChemInform Abstract: Synthesis and Crystal Structure of (S4N3)2Se2Cl10, (S4N3)2Se2Cl6 and ((S4N3)SeCl5)n.
Authors: STAMMLER H. G. , WEISS J. 
Published: May 2016

AbstractThe title compounds (III) and (IV), prepared as outlined in the scheme, are both monoclinic and crystallize in space group P21/a, Z=2 and P21/c, Z=4, respectively.
ChemInform Abstract: Michael Type Addition Reactions of Some Enamines to Arylidenepyrazolones.
Authors: ABDEL‐RAHMAN M. , ABDEL‐GHANY H. 
Published: May 2016

AbstractHeating the benzylidenepyrazolones (I) with the piperidinocyclohexene (II) in acetonitrile results in the formation of the 2‐substituted 1‐piperidinocyclohexenes (III), whereas coupling of (Ia) ‐ (Ic) with the morpholinocyclohexene (IV) under similar conditions yields the 3‐substituted 2‐morpholinocyclohexenes (V).
ChemInform Abstract: Aminolead Compounds as a New Reagent for Regioselective Ring Opening of Epoxides.
Authors: YAMADA J. , YUMOTO M. , YAMAMOTO Y. 
Published: May 2016

AbstractThe trialkyllead bromides (I) are treated with lithium diethylamide (II) to generate the trialkyllead amides (IIIa) and (IIIb).
ChemInform Abstract: Direct and Bromine‐Atom Initiated Photodecompositions of N‐Acetyl‐N‐bromohexanamide.
Authors: CHOW Y. L. , ZHAO D.‐C. 
Published: May 2016

AbstractPhotolysis of (I) in the presence of an alkene gives high yields of (II) via the imidyl radical Me‐(CH2)4‐CO‐N·‐Ac.
ChemInform Abstract: A New Amino Protecting Group Readily Removable with Near Ultraviolet Light as an Application of Electron‐Transfer Photochemistry.
Authors: HAMADA T. , NISHIDA A. , YONEMITSU O. 
Published: May 2016

AbstractThe (methoxyaryl)alkylbenzenesulfonyl chlorides (I) react with the phenethylamine (II), producing the sulfonamides (III).
ChemInform Abstract: Hydride‐Mediated Homogeneous Catalysis. Catalytic Reduction of α,β‐Unsaturated Ketones Using ((Ph3P)CuH)6 and H2.
Authors: MAHONEY W. S. , STRYKER J. M. 
Published: May 2016

AbstractHydride reduction methodology catalytic in the hydride source is demonstrated using stable copper(I) complexes and molecular hydrogen.
ChemInform Abstract: Reduction of Methylene Blue by Sulfide Ion in the Presence and Absence of Oxygen: Simulation of the Methylene Blue‐O2‐HS‐ CSTR Oscillations.
Authors: RESCH P. , FIELD R. J. , SCHNEIDER F. W. , BURGER M. 
Published: May 2016

AbstractA mechanism is proposed that reproduces the oscillations seen during the methylene blue catalyzed reduction of O2 by HS‐ in a continuous‐flow stirred tank reactor (CSTR).
ChemInform Abstract: One‐Pot Two‐Steps Synthesis of 1,2‐Diol.
Authors: FRINGUELLI F. , GERMANI R. , PIZZO F. , SAVELLI G. 
Published: May 2016

AbstractThe olefins (I) are epoxidized with MCPBA and then subjected to acidic hydrolysis, yielding the vicinal diols (II).
ChemInform Abstract: Hydrocarboxylation of Isoprene Catalyzed by Iodocarbonylrhodium Derivatives. Spectroscopic Evidence for Participation of H+···Rh(CO)2I2‐ Tight Ion Pairs and cis‐Rh(CO)2(H2O)I in Catalysis.
Authors: GARLASCHELLI L. , MARCHIONNA M. , IAPALUCCI M. C. , LONGONI G. 
Published: May 2016

AbstractHydrocarboxylation of isoprene (I), catalyzed by iodocarbonylrhodium derivatives, can be controlled to give either pyroterebic acid (IV) or its lactone (V).
ChemInform Abstract: Palladium‐Catalyzed Double Carbonylation of Alkyl Iodides Bearing a Perfluoroalkyl Group.
Authors: URATA H. , ISHII Y. , FUCHIKAMI T. 
Published: May 2016

AbstractThe fluoroalkyl iodides (I) are carbonylated in the presence of the amines (II) and a Pd catalyst to form the α‐oxo carboxamides (IV), together with the amides (V).
ChemInform Abstract: Ritter Reactions. Part 5. Further Investigation of the 3‐Azatricyclo(5.3.1.04,9)undec‐2‐ene System.
Authors: BONG I. C. C. , UNG A. T. , CRAIG D. C. , SCUDDER M. L. , BISHOP R. 
Published: May 2016

AbstractThe monohydrate of compound (I) is prepared in a Ritter reaction from (II) and acetonitrile as previously published (space group P21 with Z=2).
ChemInform Abstract: Nickel(0)‐Induced CC‐Coupling of CO2 with 1,3‐Butadiene to Linear C13‐Acids.
Authors: HOBERG H. , BAERHAUSEN D. + 
Published: May 2016

AbstractFluorinated pyridine‐nickel systems induce a new coupling reaction between 1,3‐butadiene (I) and CO2 (II) to give mixtures of the linear C13‐acid esters (IV)‐(VII) with three or four C=C double bonds and terminal carboxylic groups.
ChemInform Abstract: A Novel Radical Chain Reaction of Xanthic Anhydrides. Further Observations on the Intermediacy of Alkoxythiocarbonyl Radicals in the Barton‐McCombie Reaction.
Authors: FORBES J. E. , ZARD S. Z. 
Published: May 2016

AbstractThermolytic or photolytic cleavage of the xanthic anhydrides (I) gives the dithiocarbonates (II) via radicalic intermediates.
ChemInform Abstract: Synthesis of 7,7‐Dimethylbicyclo(3.3.0)octane Derivatives by Acylation of the 4‐Methyl‐3‐penten‐1‐ynedicobalt Hexacarbonyl Complex.
Authors: VERETENOV A. L. , GYBIN A. S. , SMIT V. A. , CHERTKOV V. A. , SHASHKOV A. S. 
Published: May 2016

AbstractStarting with isobutyraldehyde (I), the methylpentenynecobalt carbonyl complex (VI) is prepared via the intermediates (III) and (V).
ChemInform Abstract: Synthesis of a Potential Steroid Intermediate by Anionic Oxy‐Cope Rearrangement.
Authors: SATHYAMOORTHI G. , THANGARAJ K. , SRINIVASAN P. C. , SWAMINATHAN S. 
Published: May 2016

AbstractThe cyclohexenylvinylcyclohexanol (X) undergoes base‐induced ring closure to form the unsaturated bicyclic ketone (XI).
ChemInform Abstract: Synthesis of 7‐Fluoro‐9,10‐dihydro‐2‐phenanthrylalkanoic Acids.
Authors: EIRIN A. , FERNANDEZ F. , GOMEZ G. , LOPEZ C. , SANTOS A. 
Published: May 2016

AbstractThe nitrophenanthrene (I) is converted to the fluoro analogue (VI) via reduction, diazotization, and thermolysis of the diazonium hexafluorophosphate (V).
ChemInform Abstract: A Novel Method for Generation of Enolizable N‐Trimethylsilylaldimines and Application to β‐Lactam Synthesis.
Authors: UYEHARA T. , SUZUKI I. , YAMAMOTO Y. 
Published: May 2016

AbstractN,N‐Bis(trimethylsilyl)formamide (I) reacts with the organolithium compounds (II) to give the intermediate alkoxides (III) which form the aldimines (IV).
ChemInform Abstract: Five‐Membered 2,3‐Dioxoheterocycles. Part 16. Synthesis of 1,4‐Disubstituted 5‐Aryltetrahydropyrrole‐2,3‐diones by the Reaction of Diethoxalylacetone with Azomethines.
Authors: ANDREICHIKOV YU. S. , GEIN V. L. , KON'SHINA L. O. , SHAPET'KO N. N. 
Published: May 2016

AbstractThe reaction between the title compounds (I) and (II) is investigated for the first time.
ChemInform Abstract: Fischer Indolization and Related Compounds. Part 21. Direction on the Cyclization in the Fischer Indolization of Ethyl Pyruvate 2‐(p‐ or m‐Substituted Phenyl)phenylhydrazones.
Authors: ISHII H. , TAKEDA H. , HAGIWARA T. , SAKAMOTO M. , KOGUSURI K. , MURAKAMI Y. 
Published: May 2016

AbstractThe Fischer indolization reaction (FIR) of the readily available phenylhydrazones (IV) under acidic conditions gives the indoles (V) and (VI) as main products whereas the yields of (V) and (VI) are much lower in the thermal sigmatropic reaction of (IV) producing preferentially the compounds (I).
ChemInform Abstract: Synthesis and Reactions of 5‐(Tributylstannyl)isoxazoles.
Authors: KONDO Y. , UCHIYAMA D. , SAKAMOTO T. , YAMANAKA H. 
Published: May 2016

AbstractEthynyltributylstannane (I) undergoes 1,3‐dipolar cycloaddition reaction with the nitrile oxides (II) to yield the tributylstannylisoxazoles (III).
ChemInform Abstract: A Convenient One‐Pot Synthesis of 3‐Thio‐Substituted Coumarins.
Authors: AHLUWALIA V. K. , ALAUDDIN M. , KHANDURI C. H. , MEHTA V. D. 
Published: May 2016

AbstractAlkylation of the heterocyclic thiols (I) with chloroacetonitrile (II) yields the cyanomethyl sulfides (III) which undergo ring closure with the o‐hydroxybenzaldehydes (IV), forming the coumarinimines (V).
ChemInform Abstract: Synthesis of 3‐Aryl‐4‐acetyl‐1H‐pyrazolo(3,4‐b)pyridines and 3‐Aryl‐4‐acetyl‐1H‐pyrazolo(4,3‐c)pyridines.
Authors: BISAGNI E. , RAUTUREAU M. , HUEL C. 
Published: May 2016

AbstractLithiation of the 2‐chloropyridin‐4‐yl ketone acetal (I) followed by coupling with the aromatic aldehydes (II) yields the carbinols (III) which are subjected to Swern oxidation, forming the 2‐chloro‐3‐aroylpyridines (IV).
ChemInform Abstract: Alkylation and Rearrangement of Lithiated 3‐Methyl‐1,2‐benzisoxazoles.
Authors: OLIVER J. E. , WATERS R. M. , LUSBY W. R. 
Published: May 2016

AbstractThe 3‐methylbenzisoxazoles (I) are deprotonated at the methyl group upon treatment with LDA in the presence of the bromide (II) to give the 3‐undecylbenzisoxazoles (III).
ChemInform Abstract: Acylation and Oxidation of 4‐Chloro‐6‐hydroxyaminopyrimidines. Synthesis of 4‐Chloro‐6‐nitro(nitroso)pyrimidines.
Authors: YAGODINA O. V. , SEDOVA V. F. , MAMAEV V. P. 
Published: May 2016

AbstractThe chlorohydroxylaminopyrimidines (III) are coupled with the carboxylic chlorides (IV) or the isocyanates (VII) to give the acyl derivatives (V) or (VI) and the biscarbonyl compounds (VIII).
ChemInform Abstract: Oxidation of Hydroxyamino‐ and Nitrosopyrimidines. Synthesis of Substituted 2‐ and 4‐Nitropyrimidines.
Authors: MOSKALENKO G. G. , SEDOVA V. F. , MAMAEV V. P. 
Published: May 2016

AbstractOxidation of the nitrosopyrimidines (I) or (III) gives the corresponding nitro derivatives (II) or (IV), whereas from the hydroxyaminopyrimidines (V) and (VII), the azoxy compounds (VI) and (VIII) are obtained.
ChemInform Abstract: Synthesis and Structure Activity Relationship in Aryloxyalkylamines.
Authors: AGARWAL S. K. , SAXENA A. K. , JAIN P. C. , ANAND N. , SUR R. N. , SRIMAL R. C. , DHAWAN B. N. 
Published: May 2016

AbstractThree compounds of type (III) and (VII) as well as five compounds of type (XI) are prepared.
ChemInform Abstract: Piperazine Derivatives of Benzimidazole as Potential Anthelmintics. Part 1. Synthesis and Activity of Methyl‐5‐(4‐Substituted‐piperazin‐1‐yl)benzimidazole‐2‐carbamates.
Authors: SANCHEZ‐ALONSO R. M. , RAVINA E. , SANTANA L. , GARCIA‐MERA G. , SANMARTIN M. , BALTAR P. 
Published: May 2016

AbstractThe piperazinylnitroanilines (III), prepared by coupling the piperazines (I) with the chloronitroaniline (II), are reduced and subsequently treated with the S‐methylisothiourea (IV) to produce the piperazinylbenzimidazoles (V).