bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ocular Surface Squamous Neoplasia in Papillon–Lefèvre Syndrome: Outcome at Long-Term Follow-Up of 12 Years
Authors: Kaliki Swathi , Singh Swati , Gowrishankar Swarnalata , Reddy Vijay Anand P. 
Published: March 2017

Purpose:
To discuss the association between ocular surface squamous neoplasia (OSSN) and Papillon–Lefèvre syndrome (PLS) and present the long-term outcome in a patient with these diseases.

Methods:
Case report.

Results:
A 14-year-old boy presented with a raised pigmented mass lesion at the limbus in the right eye, which was clinically suggestive of OSSN. He also had palmoplantar hyperkeratosis and periodontosis suggestive of PLS. Excision biopsy of the lesion confirmed the diagnosis of OSSN. He was free of tumor recurrence for 2 years and was lost to follow-up thereafter. Seven years later, the patient presented with diffuse tumor recurrence with orbital extension in the right eye, regional lymph node metastasis, and ipsilateral parotid gland infiltration. The patient underwent exenteration of the right orbital contents, right parotidectomy, and radical neck dissection followed by concomitant external beam radiotherapy and systemic chemotherapy. Eleven years from initial presentation, the patient was detected to have OSSN in the contralateral eye and was managed by wide excision biopsy and adjuvant cryotherapy. One year after detection of OSSN in the left eye, the patient was found to have systemic metastases to the lungs and brain. The patient died of the disease within 3 months of detection of systemic metastasis.

Conclusions:
OSSN in PLS is associated with poor prognosis.
Cranium-Penetrating Mass Detected by Ultrasound Expedited Management of Langerhans Cell Histiocytosis
Authors: Morgan Brian , Lau Hsien Lee , Yellin Sharon 
Published: March 2017

Abstract
A 6-year-old boy presented to the pediatric emergency department with a unilateral 5 × 3-cm superficial mass on the postauricular region growing for 1 month. Point-of-care ultrasound was used to evaluate the mass, which revealed a complex cystic mass penetrating the temporal bone. After confirmatory magnetic resonance imaging, the patient was transferred for neurosurgical evaluation, and the tumor was excised. Pathology revealed Langerhans cell histiocytosis.
Serotonin Syndrome in a Pediatric Patient After Vilazodone Ingestion
Authors: Laliberte Benjamin , Kishk Omayma A. 
Published: March 2017

Abstract
Serotonin syndrome (SS) is a serious toxicity that manifests with symptoms such as tremor, hyperthermia, agitation, and altered mental status that may lead to seizures, coma, or death. Selective serotonin reuptake inhibitors may precipitate SS, particularly in combination with other drugs that possess serotonergic activity. We present a case of SS in a 14-month-old after an ingestion of the selective serotonin reuptake inhibitor vilazodone.
Concurrent Validity Between Live and Home Video Observations Using the Alberta Infant Motor Scale
Authors: Boonzaaijer Marike , van Dam Ellen , van Haastert Ingrid C. , Nuysink Jacqueline 
Published: March 2017

Purpose:
Serial assessment of gross motor development of infants at risk is an established procedure in neonatal follow-up clinics. Assessments based on home video recordings could be a relevant addition.

Methods:
In 48 infants (1.5-19 months), the concurrent validity of 2 applications was examined using the Alberta Infant Motor Scale: (1) a home video made by parents and (2) simultaneous observation on-site by a pediatric physical therapist. Parents' experiences were explored using a questionnaire.

Results:
The intraclass correlation coefficient agreement between live and home video assessment was 0.99, with a standard error of measurement of 1.41 items. Intra- and interrater reliability: intraclass correlation coefficients were more than 0.99. According to 94% of the parents, recording their infant's movement repertoire was easy to perform.

Conclusion:
Assessing the Alberta Infant Motor Scale based on home video recordings is comparable to assessment by live observation. The video method is a promising application that can be used with low burden for parents and infants.
The factors contributing to construction accidents in Pakistan
Authors: Zahoor Hafiz , Chan Albert P.C. , Gao Ran , Utama Wahyudi P. 
Published: March 2017

Purpose
The highest number of accidents in proportion to the employment rate is found in construction industry among all industries in Pakistan. The purpose of this paper is to identify and prioritize the contributory factors of accident causation that can significantly reduce the rate of accident in the construction industry.

Design/methodology/approach
In total, 32 contributory factors of accident causation were identified through a triangulation strategy comprising eight face-to-face semi-structured interviews with the academic and industry experts coupled with a comprehensive literature review. Delphi survey was then conducted among the four respondent groups (clients, contractors, safety official and academia) to prioritize these factors. A consensus was achieved among the respondent groups after conducting two rounds of Delphi survey. Finally, the results were validated using the technique of inter-rater agreement (IRA) analysis.

Findings
All the shortlisted accident causation factors were graded as “important” to “extremely important”. Moreover, a “moderate” to “strong level” agreement was developed among the respondent groups. The three most significant factors were highlighted as “poor enforcement of safety rules and regulations by the Government agencies”, “insufficient allocation of safety budget and safety incentives by the client”, and “insufficient provision of safety training and resources by the contractor”.

Practical implications
The findings will help the key stakeholders to prioritize their energies towards achieving zero accident in the construction industry. Moreover, addition of academic experts as one of the respondent groups will enhance the linkages between the academia and the industry practitioners.

Originality/value
Besides highlighting the underlying causes of construction accidents in Pakistan, a detailed methodology is presented in this study for the analysis and validation of the Delphi survey data, which can be extrapolated in other regions and industries for elements prioritization. The findings of the study can also be generalized for other developing countries having similar work environment. The results validation through the use of IRA analysis is an addition to the field of construction safety research. The study also authenticates the applicability of IRA analysis to assess the agreement level among the respondents.
Financial self-efficacy: a determinant of financial inclusion
Authors: Mindra Rachel , Moya Musa , Zuze Linda Tia , Kodongo Odongo 
Published: March 2017

PurposeThe purpose of this paper is to examine the relationship between financial self-efficacy (FSE) and financial inclusion (FI) among individual financial consumers in Uganda.Design/methodology/approachUsing a quantitative approach and cross-sectional research design, a sample of 400 individuals from urban Central and rural Northern Uganda was drawn. SPSS and AMOS™ 21, regression analysis and structural equation models were used to establish the hypothesized relationship between FSE and FI.FindingsThe results suggest a strong positive and significant relationship between FSE and FI. The results further suggest that other variables which were controlled for, such as age and gender, had significant influence on an individual’s usage of formal financial services.Research limitations/implicationsThe study was assessed using both potential and actual consumers of financial services collectively. However, if separately assessed, possibly there would be a variation in behavioral responses toward FI.Practical implicationsFormal financial service providers need to enhance individuals’ levels of confidence in management of finances and utilization of formal financial products and services, so that the financial consumers can realize the changes in financial behavior and consequently FI.Social implicationsThe enhancement of individuals’ level of confidence in evaluating the available financial service options will guide them to take financial decisions that will improve their livelihood.Originality/valueThe results contribute toward the limited empirical and theoretical evidence for FSE and FI from a behavioral demand-side perspective.
Sidney J. Levy: an autobiography
Authors: Levy Sidney Jay 
Published: March 2017

Purpose
This autobiography sums up the life story of one of the contributors to the history of inquiry and instruction in the field of marketing, with special attention to the historical developments that have influenced the study of consumer behavior and the concept of branding.

Design/methodology/approach
This paper is an autobiographical essay, a personal history.

Findings
The reminiscence illustrates the way life experiences evolve, showing the interaction among personal growth, education, career choices and work experience that led to Professor Levy’s contributions to the field of marketing education and its research literature.

Originality/value
The paper describes a unique life, and an unusual explication of the personal life sources of influential ideas. It is novel in its large perspective and integrative narrative, and the unusual exposure of its various conceptual issues and links. It should be of interest to marketing historians, managers and scholars of marketing education.
Towards a theoretical mashup for studying posthuman/postsocial ethics
Authors: Buzato Marcelo El Khouri 
Published: March 2017

Purpose
This paper aims to propose a theoretical arrangement for the study of applied computer and information ethics carried out in an interdisciplinary and a democratic manner by which the information and communications technologies are seen as an ethical environment, and human-computer couplings are seen as hybrid moral agents.

Design/methodology/approach
New ethical issues emerge dynamically in such environment which must be interpreted according to human sentience and computer ontology. To attribute moral meaning to acts perpetrated by human-computer hybrids, a hybrid of two semiotics must be likely used that bridge the gap between signs and things from opposite directions.

Findings
The author argues that ecosocial dynamics and material semiotics can be harnessed together as in a theoretical mashup for that purpose, and that such harnessing will allow us to engage with a posthumanist/post-social ethics here and now.

Originality/value
The originality of the proposal resides in bringing hybridity to the center of the picture, forcing interdisciplinary teams to engage with one unified, even if hybrid, agency regardless of conflicting ontologies and epistemologies.
Research watch: is social inclusion for service users increased when mental health professionals “come out” as service users?
Authors: Holttum Sue 
Published: March 2017

Purpose
This paper discusses two recent studies of mental health professionals who have experience of mental distress, one in the USA and one in Australia. The purpose of this paper is to highlight different experiences, first of largely concealing their experience, and second of disclosing and using it.

Design/methodology/approach
The Australian study examined the barriers experienced by mental health professionals, including trainees, in relation to seeking help. The USA study reported on a sample of mental health professionals who were doing well, including leaders of services, despite current or past mental distress.

Findings
Both studies included more psychologists than other mental health professionals. Australian mental health professionals reported similar fears and barriers to those found in other studies, in addition to concern about their colleagues’ duty to report impairment to the regulating body. Professionals in the USA-based study were described as potentially helpful in reducing stigma about mental distress because their achievements demonstrated that recovery is possible. However, many of them were also cautious about who they disclosed to, and wanted further reduction in stigma and discrimination.

Originality/value
The Australian study highlighted specifically that the requirement to report impairment to the regulator deterred people from disclosing distress at work, making it less likely that they would get help. The USA-based study was ground-breaking in documenting achievements of a substantial sample of mental health professionals with experience of mental distress. Potentially more professionals being “out and proud” might help increase recovery and social inclusion for service users more generally.
Bridging the discursive gap between lay and medical discourse in care coordination
Authors: Sheaff Rod , Halliday Joyce , Byng Richard , Øvretveit John , Exworthy Mark , Peckham Stephen , Asthana Sheena 
Published: March 2017

AbstractFor older people with multiple chronic co‐morbidities, strategies to coordinate care depend heavily on information exchange. We analyse the information‐sharing difficulties arising from differences between patients’ oral narratives and medical sense‐making; and whether a modified form of ‘narrative medicine’ might mitigate them. We systematically compared 66 general practice patients’ own narratives of their health problems and care with the contents of their clinical records. Data were collected in England during 2012–13. Patients’ narratives differed from the accounts in their medical record, especially the summary, regarding mobility, falls, mental health, physical frailty and its consequences for accessing care. Parts of patients’ viewpoints were never formally encoded, parts were lost when clinicians de‐coded it, parts supplemented, and sometimes the whole narrative was re‐framed. These discrepancies appeared to restrict the patient record's utility even for GPs for the purposes of risk stratification, case management, knowing what other care‐givers were doing, and coordinating care. The findings suggest combining the encoding/decoding theory of communication with inter‐subjectivity and intentionality theories as sequential, complementary elements of an explanation of how patients communicate with clinicians. A revised form of narrative medicine might mitigate the discursive gap and its consequences for care coordination.
Sewing needles in the abdominal cavity assumed to have been ingested and to have penetrated the GI tract 40 years ago: A case report
Authors: Yamaguchi Naoya , Hiramatsu Kazuhiro , Shibata Yoshihisa , Yoshihara Motoi , Aoba Taro , Kamiya Tadahiro , Koike Yoshio , Fujita Takeru , Maeda Chikara , Ito Kisuke , Kanbara Yuichi , Nishimura Motonobu , Kobayashi Ryutarou , Dei Hideyuki , Takimoto Aitaro , Nonaka Yukiko , Kato Takehito 
Published: March 2017

AbstractA 60‐year old woman had been hospitalized in a psychiatric hospital for 40 years for schizophrenia. An X‐ray was performed when she fell, which showed needles in the abdominal field. After additional examinations and questioning, the patient was diagnosed with needles in the abdominal cavity, which were assumed to have been ingested and to have perforated the GI tract 40 years ago. They were removed by laparoscopic surgery. The needles were found in the omentum and near the left ovary. There were no inflammatory reactions around them. There have been previous reports about the removal of intra‐abdominal foreign bodies, but foreign body reaction occurred in most of the reports. Our case had the longest period from ingestion of the foreign bodies to their removal. Laparoscopy and intraoperative fluoroscopy are useful for removing intra‐abdominal foreign bodies because of their ability to help discriminate between structures and to navigate in real time.
An Eye Tracking Investigation of Color–Location Binding in Infants' Visual Short‐Term Memory
Authors: Oakes Lisa M. , Baumgartner Heidi A. , Kanjlia Shipra , Luck Steven J. 
Published: March 2017

Two experiments examined 8‐ and 10‐month‐old infants' (N = 71) binding of object identity (color) and location information in visual short‐term memory (VSTM) using a one‐shot change detection task. Building on previous work using the simultaneous streams change detection task, we confirmed that 8‐ and 10‐month‐old infants are sensitive to changes in binding between identity and location in VSTM. Further, we demonstrated that infants recognize specifically what changed in these events. Thus, infants' VSTM for binding is robust and can be observed in different procedures and with different stimuli.
Neonatal exchange transfusions in tertiary and non‐tertiary hospital settings, New South Wales, 2001–2012
Authors: Chessman Julia C , Bowen Jennifer R , Ford Jane B 
Published: March 2017

AimTo describe neonatal exchange transfusions in New South Wales (NSW) before and after release in January 2007 of a NSW Health guideline regarding exchange transfusions in tertiary and non‐tertiary hospitals.MethodsThe study population included neonates receiving exchange transfusion in NSW hospitals, 2001–2012. Linked birth and hospital data for mothers and babies were used to describe birth characteristics and maternal and neonatal conditions. Exchange transfusions were identified in hospital data and compared for 2001–2006 and 2007–2012. Maternal and neonatal characteristics were compared with χ2 and Wilcoxon signed‐rank tests.ResultsBetween 2001 and 2012, there were 286 exchange transfusions performed for 281 neonates in NSW hospitals. The number of exchange transfusions decreased from 187 in 184 neonates for 2001–2006 to 99 in 97 neonates 2007–2012 (P < 0.001). The percentage of exchange transfusions performed at tertiary hospitals increased from 85% in 2001–2006 to 91% in 2007–2012, although this was not statistically significant (P = 0.16). Most neonates requiring exchange transfusion were born in tertiary hospitals: 62% for 2001–2006 and 69% for 2007–2012. Among those born in a non‐tertiary hospital, the percentage transferred or admitted to a tertiary hospital for exchange transfusion was 63% in 2001–2006 and 77% in 2007–2012.ConclusionBetween 2001 and 2012, there was a decrease in neonatal exchange transfusions in NSW. After the 2007 guideline there was a non‐significant increase in the proportion of exchange transfusions performed at tertiary hospitals. Although rare, exchange transfusions are still expected to occur occasionally in non‐tertiary hospitals, requiring continuing support for this procedure in these settings.
Exploring the Landscape of Diazabicyclooctane (DBO) Inhibition: Avibactam Inactivation of PER-2 β-Lactamase
Authors: Ruggiero Melina , Papp-Wallace Krisztina M. , Taracila Magdalena A. , Mojica Maria F. , Bethel Christopher R. , Rudin Susan D. , Zeiser Elise T. , Gutkind Gabriel , Bonomo Robert A. , Power Pablo 
Published: March 2017

ABSTRACT

PER β-lactamases are an emerging family of extended-spectrum β-lactamases (ESBL) found in Gram-negative bacteria. PER β-lactamases are unique among class A enzymes as they possess an inverted omega (Ω) loop and extended B3 β-strand. These singular structural features are hypothesized to contribute to their hydrolytic profile against oxyimino-cephalosporins (e.g., cefotaxime and ceftazidime). Here, we tested the ability of avibactam (AVI), a novel non-β-lactam β-lactamase inhibitor to inactivate PER-2. Interestingly, the PER-2 inhibition constants (i.e.,
k
2
/
K
= 2 × 10
3
± 0.1 × 10
3
M
−1
s
−1
, where
k
2
is the rate constant for acylation (carbamylation) and
K
is the equilibrium constant) that were obtained when AVI was tested were reminiscent of values observed testing the inhibition by AVI of class C and D β-lactamases (i.e.,
k
2
/
K
range of ≈10
3
M
−1
s
−1
) and not class A β-lactamases (i.e.,
k
2
/
K
range, 10
4
to 10
5
M
−1
s
−1
). Once AVI was bound, a stable complex with PER-2 was observed via mass spectrometry (e.g., 31,389 ± 3 atomic mass units [amu] → 31,604 ± 3 amu for 24 h). Molecular modeling of PER-2 with AVI showed that the carbonyl of AVI was located in the oxyanion hole of the β-lactamase and that the sulfate of AVI formed interactions with the β-lactam carboxylate binding site of the PER-2 β-lactamase (R220 and T237). However, hydrophobic patches near the PER-2 active site (by Ser70 and B3-B4 β-strands) were observed and may affect the binding of necessary catalytic water molecules, thus slowing acylation (
k
2
/
K
) of AVI onto PER-2. Similar electrostatics and hydrophobicity of the active site were also observed between OXA-48 and PER-2, while CTX-M-15 was more hydrophilic. To demonstrate the ability of AVI to overcome the enhanced cephalosporinase activity of PER-2 β-lactamase, we tested different β-lactam–AVI combinations. By lowering MICs to ≤2 mg/liter, the ceftaroline-AVI combination could represent a favorable therapeutic option against
Enterobacteriaceae
expressing
bla
PER-2
. Our studies define the inactivation of the PER-2 ESBL by AVI and suggest that the biophysical properties of the active site contribute to determining the efficiency of inactivation.
Experience of miscarriage: an interpretative phenomenological analysis
Authors: Meaney S , Corcoran P , Spillane N , O'Donoghue K 
Published: March 2017

ObjectiveThe objective of the study was to explore the experiences of those who have experienced miscarriage, focusing on men's and women's accounts of miscarriage.DesignThis was a qualitative study using a phenomenological framework. Following in-depth semistructured interviews, analysis was undertaken in order to identify superordinate themes relating to their experience of miscarriage.SettingA large tertiary-level maternity hospital in Ireland.ParticipantsA purposive sample of 16 participants, comprising 10 women and 6 men, was recruited.Results6 superordinate themes in relation to the participant's experience of miscarriage were identified: (1) acknowledgement of miscarriage as a valid loss; (2) misperceptions of miscarriage; (3) the hospital environment, management of miscarriage; (4) support and coping; (5) reproductive history; and (6) implications for future pregnancies.ConclusionsOne of the key findings illustrates a need for increased awareness in relation to miscarriage. The study also indicates that the experience of miscarriage has a considerable impact on men and women. This study highlights that a thorough investigation of the underlying causes of miscarriage and continuity of care in subsequent pregnancies are priorities for those who experience miscarriage. Consideration should be given to the manner in which women who have not experienced recurrent miscarriage but have other potential risk factors for miscarriage could be followed up in clinical practice.
Training zoo animals for better welfare, better nursing
Authors: Deane Kelly 
Published: March 2017

Background: Historically, methods used to carry out veterinary procedures in animals within a zoo usually involved manual restraint or darting as a first choice. Aim: To see whether any animal can be trained and if that trained behaviour will improve animal welfare through allowing veterinary procedures to be carried out. Method: A range of species were looked at retrospectively to establish if they could be trained and how that affected welfare. A study was then carried out using a group of Zebras, who were trained for hand injection for their annual vaccination. Results: Case studies indicated that any animal can be trained and the results of using training could improve their welfare. The use of remote delivery systems, such as darts, resulted in pain, stress and deferred aggression. Conclusion: A number of different species can be trained to carry out a behaviour, if this is applied in all animals the need for restraint and general anaesthesia could be reduced. This would result in improved welfare to zoo animals, but can be applied to all patients, exotic and small animal.