bluuebunny/crossref_metadata_2025_split huggingface dataset:
Didactique de l’écriture : le déjà-là des pratiques d’écriture numérique
Authors: Penloup Marie-Claude 
Published: April 2017

Dans un contexte d’explosion des pratiques d’écriture numériques des élèves hors situation scolaire, l’article propose la prise en compte de ce « déjà-là » dans la classe de français. Ancrée en sociolinguistique, la réflexion s’inscrit dans la lignée des travaux menés sur les écrits ordinaires mais emprunte aussi aux cultural studies . L’écriture numérique non scolaire y est envisagée comme une aubaine pour l’enseignement du français au motif qu’elle offre l’occasion d’étudier linguistiquement une variété spécifique du français écrit et, dans le même temps, d’engager une didactique de la variation langagière dont l’absence est posée comme préjudiciable à la maitrise de la norme. Mais l’article invite aussi à s’intéresser, à travers les témoignages de trois futures enseignantes, à ces écrits narratifs en ligne que sont les fanfictions et aux apprentissages de l’écriture qu’ils engendrent au sein de communautés bienveillantes. Il y a là un champ de recherche encore trop peu investi par les didacticiens du français.
De la compétence littéraire à l’expérience du pouvoir des mots
Authors: Dall’Armellina Luc 
Published: April 2017

À partir de l’expérience d’un atelier d’écritures mené en 2014 à l’université de Cergy-Pontoise, avec les étudiants du master « Médiation Culturelle », cet article propose d’interroger la place des pratiques artistiques à l’école et à l’université. Il entend de le faire en regard du statut de l’œuvre d’art, des particularités des écritures numériques et des cultures institutionnelles dans lesquelles elles prennent place. Il montre que, si le dispositif collaboratif de l’atelier s’appuie sur une convivialité fondatrice, il révèle aussi une vision élargie de l’élève comme sujet sensible. L’écriture créative ne vise donc (sans pour autant les écarter) ni le savoir disciplinaire ni la maitrise didactique, mais l’expérience créative de la singularité.
La Réaction parfumée : les « petits musqués » de la Révolution
Authors: Perras Jean-Alexandre 
Published: April 2017

La figure politique du muscadin est aussi persistante que l’odeur de musc dont elle tire son nom. Si cette construction polémique jacobine a d’abord permis d’incarner les ennemis de la Révolution, elle est devenue au cours du xix e siècle le symbole de l’aristocratie réactionnaire, de ses ridicules et de ses excès. Réels ou supposés, ces usages politiques du parfum permettent de montrer comment l’olfaction contribue à constituer, sur un mode polémique des catégories sociales.
Lettres parfumées, correspondances fatales
Authors: Krueger Cheryl 
Published: April 2017

Cet article se concentre sur la présence aromatique de deux lettres fictives que nous lisons dans le cadre des pratiques sociales du xix e siècle relatives au parfum. Ces épisodes épistolaires mettent en scène la complexité de l’interprétation des odeurs socialement déchiffrables, en reliant la fragrance au déséquilibre physique et psychologique. Comme les écrits extra-littéraires de l’époque, ces romans expriment une confusion sournoise entre les miasmes et les fragrances cosmétiques, qui reflète et alimente des attitudes contradictoires à l’égard de la femme qui se parfume.
Integrated Education Management System via Cloud Computing
Authors: El-Seoud Samir Abou , AboGamie Eslam Ahmed , Salama Mostafa 
Published: April 2017

<p>In this work, we present a framework to integrate the functionalities of the Enterprise Resource Planning (ERP) with the University academic and management functionalities at the British University in Egypt , in order to produce a University Resource Planning (URP) that facilitates the integration between educational and management processes within higher educational institutions.</p><p>Our ERP systems should be enabled to:</p><ul><li>Automate admissions. Eliminate manual processes and save significant staff time by enabling prospective students to apply online through a self-service portal. Provide one-stop student access. Allow students to enroll, register, and pay for courses through the portal.</li><li>Simplify records management. With a single system for all your data needs—and a single digital record for each student—any department on campus can find the student information they need.</li><li>Engage faculty. Give faculty the means to enter and update grades, and have personalized access to timely, accurate, and institution-wide information.</li><li>Manage resources. Manage personnel, funds and processes more transparently.</li><li>Strengthen decision-making. Track the metrics you need to guide day-to-day operations, meet reporting requirements, and engage your organization.</li></ul><em>Keywords:</em> Integrated management systems for higher education, eLearning, MOODLE, cloud technology, systems integrity
4PD Functionalized Dendrimers: A Flexible Tool for In Vivo Gene Silencing of Tumor-Educated Myeloid Cells
Authors: Zilio Serena , Vella Jennifer L. , De la Fuente Adriana C. , Daftarian Pirouz M. , Weed Donald T. , Kaifer Angel , Marigo Ilaria , Leone Kevin , Bronte Vincenzo , Serafini Paolo 
Published: April 2017

Abstract
Myeloid cells play a key role in tumor progression and metastasis by providing nourishment and immune protection, as well as facilitating cancer invasion and seeding to distal sites. Although advances have been made in understanding the biology of these tumor-educated myeloid cells (TEMCs), their intrinsic plasticity challenges our further understanding of their biology. Indeed, in vitro experiments only mimic the in vivo setting, and current gene-knockout technologies do not allow the simultaneous, temporally controlled, and cell-specific silencing of multiple genes or pathways. In this article, we describe the 4PD nanoplatform, which allows the in vivo preferential transfection and in vivo tracking of TEMCs with the desired RNAs. This platform is based on the conjugation of CD124/IL-4Rα–targeting peptide with G5 PAMAM dendrimers as the loading surface and can convey therapeutic or experimental RNAs of interest. When injected i.v. in mice bearing CT26 colon carcinoma or B16 melanoma, the 4PD nanoparticles predominantly accumulate at the tumor site, transfecting intratumoral myeloid cells. The use of 4PD to deliver a combination of STAT3- and C/EBPβ-specific short hairpin RNA or miR-142-3p confirmed the importance of these genes and microRNAs in TEMC biology and indicates that silencing of both genes is necessary to increase the efficacy of immune interventions. Thus, the 4PD nanoparticle can rapidly and cost effectively modulate and assess the in vivo function of microRNAs and mRNAs in TEMCs.
Extravillous Trophoblast and Endothelial Cell Crosstalk Mediates Leukocyte Infiltration to the Early Remodeling Decidual Spiral Arteriole Wall
Authors: Choudhury Ruhul H. , Dunk Caroline E. , Lye Stephen J. , Aplin John D. , Harris Lynda K. , Jones Rebecca L. 
Published: April 2017

Abstract
Decidual spiral arteriole (SpA) remodeling is essential to ensure optimal uteroplacental blood flow during human pregnancy, yet very little is known about the regulatory mechanisms. Uterine decidual NK (dNK) cells and macrophages infiltrate the SpAs and are proposed to initiate remodeling before colonization by extravillous trophoblasts (EVTs); however, the trigger for their infiltration is unknown. Using human first trimester placenta, decidua, primary dNK cells, and macrophages, we tested the hypothesis that EVTs activate SpA endothelial cells to secrete chemokines that have the potential to recruit maternal immune cells into SpAs. Gene array, real-time PCR, and ELISA analyses showed that treatment of endothelial cells with EVT conditioned medium significantly increased production of two chemokines, CCL14 and CXCL6. CCL14 induced chemotaxis of both dNK cells and decidual macrophages, whereas CXCL6 also induced dNK cell migration. Analysis of the decidua basalis from early pregnancy demonstrated expression of CCL14 and CXCL6 by endothelial cells in remodeling SpAs, and their cognate receptors are present in both dNK cells and macrophages. Neutralization studies identified IL-6 and CXCL8 as factors secreted by EVTs that induce endothelial cell CCL14 and CXCL6 expression. This study has identified intricate crosstalk between EVTs, SpA cells, and decidual immune cells that governs their recruitment to SpAs in the early stages of remodeling and has identified potential key candidate factors involved. This provides a new understanding of the interactions between maternal and fetal cells during early placentation and highlights novel avenues for research to understand defective SpA remodeling and consequent pregnancy pathology.
Effects of polymorphisms at &lt;i&gt;LEP&lt;/i&gt;, &lt;i&gt;CAST&lt;/i&gt;, &lt;i&gt;CAPN1&lt;/i&gt;, &lt;i&gt;GHR&lt;/i&gt;, &lt;i&gt;FABP4&lt;/i&gt; and &lt;i&gt;DGAT1&lt;/i&gt; genes on fattening performance and carcass traits in Simmental bulls
Authors: Ardicli Sena , Dincel Deniz , Samli Hale , Balci Faruk 
Published: April 2017

Abstract. The aim of this study was to investigate the effects of single nucleotide polymorphisms (SNPs) at six candidate genes (LEP, CAST, CAPN1, GHR, FABP4 and DGAT1) on fattening performance and carcass traits of Simmental bulls in Turkey. The analysis covered a total of 81 Simmental bulls grown on a private farm that were randomly selected for their fattening period for use in this study. Genotyping was performed using the PCR-RFLP method. The S20T polymorphism at the CAST gene and the G316A polymorphism at the CAPN1 gene were associated with variation in final weight, fattening period, weight gain and average daily gain (P < 0.05). In addition, LEP A80V had a significant effect on hot and chilled carcass weight and dressing percentage (P < 0.05). There was no association between GHR S555G, FABP4 V110M and DGAT1 K232A markers with the traits analysed. These results suggested that focusing on the novel effects of LEP, CAST and CAPN1 gene polymorphisms on meat production traits might be useful for marker-assisted selection in Simmental cattle.
Modelling sun-induced fluorescence and photosynthesis with a land surface model at local and regional scales in northern Europe
Authors: Thum Tea , Zaehle Sönke , Köhler Philipp , Aalto Tuula , Aurela Mika , Guanter Luis , Kolari Pasi , Laurila Tuomas , Lohila Annalea , Magnani Federico , Van Der Tol Christiaan , Markkanen Tiina 
Published: April 2017

Abstract. Recent satellite observations of sun-induced chlorophyll fluorescence (SIF) are thought to provide a large-scale proxy for gross primary production (GPP), thus providing a new way to assess the performance of land surface models (LSMs). In this study, we assessed how well SIF is able to predict GPP in the Fenno-Scandinavian region and what potential limitations for its application exist. We implemented a SIF model into the JSBACH LSM and used active leaf-level chlorophyll fluorescence measurements (Chl F) to evaluate the performance of the SIF module at a coniferous forest at Hyytiälä, Finland. We also compared simulated GPP and SIF at four Finnish micrometeorological flux measurement sites to observed GPP as well as to satellite-observed SIF. Finally, we conducted a regional model simulation for the Fenno-Scandinavian region with JSBACH and compared the results to SIF retrievals from the GOME-2 (Global Ozone Monitoring Experiment-2) space-borne spectrometer and to observation-based regional GPP estimates. Both observations and simulations revealed that SIF can be used to estimate GPP at both site and regional scales. At regional scale the model was able to simulate observed SIF averaged over 5 years with r2 of 0.86. The GOME-2-based SIF was a better proxy for GPP than the remotely sensed fAPAR (fraction of absorbed photosynthetic active radiation by vegetation). The observed SIF captured the seasonality of the photosynthesis at site scale and showed feasibility for use in improving of model seasonality at site and regional scale.
Weighted Steklov problem under nonresonance conditions
Authors: Doumatè Jonas , Marcos Aboubacar 
Published: April 2017

We deal with the existence of weak solutions of the nonlinear problem $-\Delta_{p}u+V|u|^{p-2}u$ in a bounded smooth domain $\Omega\subset \mathbb{R}^{N}$ which is subject to the boundary condition $|\nabla u|^{p-2}\frac{\partial u}{\partial \nu}=f(x,u)$. Here $V\in L^{\infty}(\Omega)$ possibly exhibit both signs which leads to an extension of particular cases in literature and $f$ is a Carathéodory function that satisfies some additional conditions. Finally we prove, under and between nonresonance condtions, existence results for the problem.
Malignant melanoma of the female urethra
Authors: Terada Tadashi 
Published: April 2017

Backgrounds: Malignant melanoma (MM) of urethra is extremely rare; only 84 cases have been reported in PubMed search.Case: An 84-year-old woman presented dysuria. Physical and endoscopic examination revealed a polypoid tumor in proximal urethra, and endoscopic tumorectomy was performed. The tumor could not be seen in outer genitalia. Grossly, the tumor is brownish soft tumor measuring 15 mm × 26 mm × 23 mm. Multiple sections were made and immunohistochemical procedures were performed. Microscopically, malignant epithelioid cells with brown pigment were seen to proliferate and invade. The size of tumor was circa 13 mm × 21 mm × 18 mm. The depth of invasion was 10 mm (pT4), but it was not clear whether the marginal tissue status is positive or negative. Lymphovascular permeation seen, yet no obvious vascular invasion was noted. The brown pigment was found to be melanin by Masson-Fontana stain. Immunohistochemical study showed tumor cells were positive for vimentin, S100 protein, HMB45, Melan A, p53, and Ki67 (labeling = 85%), KIT and PDGFRA, while they were negative for cytokeratins. Genetic analysis of paraffin-embedded tumor tissue identified no mutations in hot spots of KIT and PDGFRA genes. No apparent metastatic lesions were seen after the diagnosis. The outcome of the patient is unknown because the patient was referred to a large hospital specializing in cancer treatment.Conclusions: The author presented a very rare case of MM of the proximal urethra. The MM showed typical histochemical and immunohistochemical features. No mutations of KIT and PDGFRA were seen.
Bill: A Portrait of Discontinuties
Authors: Halliday Arthur 
Published: April 2017

A dialogue and a reflection are offered as a way of structuring the author’s thoughts about the life and personality of a dead friend (the dialogue), and his reflection on why he wrote the first dialogue as he did. In particular, the dialogue seeks to present the dead man as confusing to ‘read’. The reflection considers how much attention is given in the first to different aspects of the friend’s life, and offers possible reasons for these choices. Reasons include the personal characteristics of the author highlighted by his friendship with the dead man, and the author’s wish to reflect obliquely something of the felt experience of being the dead man’s friend. This dialogue was submitted to EJLW on August 7th, and published on April 9th 2017. Arthur Halliday is a pseudonym.
Moscow Interdisciplinary Conference on Autobiography
Authors: Rollings Thomas 
Published: April 2017

The conference devoted to “Autobiographical writings in an interdisciplinary research environment: people, texts, practices” was held on 1–2 June 2016 in Moscow at the National Research University The Higher School of Economics (HSE). The conference aimed to promote the study of first-person writings as the product of specific social practices and marked a modest step forward in the study of autobiography in Russia. This article was submitted to EJLW on October 21st 2016 and published on April 9th 2017.
Finding a Tongue: Autobiography Beyond Definition
Authors: Prade-Weiss Juliane 
Published: April 2017

The outset of Joyce’s A Portrait of the Artist as a Young Man presents a stage of life and language that is commonly evoked and, at the same time, systematically avoided in autobiographies as well as theoretical approaches to language: infancy. This textual strategy refers back to Augustine’s Confessiones, one of the most canonical autobiographies, reading it as a mainstay for an unconventional hypothesis: Rather that understanding infancy as an early stage of, or even before, language, Joyce expounds that the condition called infancy – the openness for receiving language while being unable to master it – accompanies all speech, be it childlike or eloquent. The article analyses Joyce’s text as one instance of a general paradox of autobiographical writing: initial aphasia. Setting out with birth or infancy, autobiographical texts precede articulate discourse. In Joyce, this paradox appears as starting point for a poetical – rather than theoretical – thinking about language, and language acquisition. This article was submitted on September 22nd 2015, and published on April 9th 2017.
A review of routinely collected data studies in urology: Methodological considerations, reporting quality, and future directions
Authors: Welk Blayne , Kwong Justin 
Published: April 2017

Studies using routinely collected data (RCD) are common in the urological literature; however, there are important considerations in the creation and review of RCD discoveries. A recent reporting guideline (REporting of studies Conducted using Observational Routinely-collected health Data, RECORD) was developed to improve the reporting of these studies. This narrative review examines important considerations for RCD studies. To assess the current level of reporting in the urological literature, we reviewed all the original research articles published in Journal of Urology and European Urology in 2014, and determined the proportion of the RECORD checklist items that were reported for RCD studies. There were 56 RCD studies identified among the 608 articles. When the RECORD items were considered applicable to the specific study, they were reported in 52.5% of cases. Studies most consistently (>80% of them) reported the names of the data sources, the study time frame, the extent to which the authors could access the database source, the patient selection, and discussed missing data. Few studies (<25%) discussed validation of key coding elements, details on data-linkage, data-cleaning, the impact of changing eligibility over time, or provided the complete list of coding elements used to define key study variables. Reporting factors specifically relevant in RCD studies may serve to increase the quality of these studies in the urological literature. With increased technological integration in healthcare and the proliferation of electronic medical records, RCD will continue to be an important source for urological research.
Impact of smartphone digital photography, email, and media communication on emergency room visits post-hypospadias repair
Authors: Chua Michael E. , Saunders Megan A. , Bowlin Paul R. , Ming Jessica M. , Iglesias Lopes Roberto , Farhat Walid A. , Dos Santos Joana 
Published: April 2017

Introduction: Advances in communication technology are shaping our medical practice. To date, there is no clear evidence that this mode of communication will have any effect on unnecessary postoperativeemergency room (ER) visits. We aim to evaluate the effect of email and media communication with application of smartphone digital photography on post-hypospadias repair ER visit rates.Methods: This prospective cohort study included all patients who underwent hypospadias repair performed by a single surgeon from October 2014 to November 2015. Patients were categorized intotwo groups: Group A consented for smartphone photography and email communication and Group B declined. Reason for ER visits within 30 days postoperatively was assessed by another physician, who was blinded of patient group assignment. The reasons were categorized as: unnecessary ER visit, indicated ER visit, or visit unrelated to hypospadias surgery. Chi-square test and T-test were used for statistical analysis. Relative risk (RR) and corresponding 95% confidence interval (CI) were also calculated. Statistical significance was set at p<0.05.Results: Over a 14-month period, 96 patients underwent hypospadias repair (81 in Group A, 15 in Group B 5). No significant difference was noted between groups for overall ER return rate (RR 0.46, 95% CI 0.21, 1.0). However, the number of ER visits for wound check not requiring intervention was significantly lower in Group A than in Group B (RR 0.14, 95% CI 0.035, 0.56); likewise, a higher number of ER visits requiring intervention was noted in Group A compared with Group B, although statistically this was not significant (RR 1.67, 95% CI 0.23, 12.21).Conclusions: Email communication with the use of smartphone digital photography significantly reduced the number of unnecessary ER visits for post-hypospadias wound checks.
Distribution of Dehalococcoides 16S rRNA and Dehalogenase Genes in Contaminated Sites
Authors: Yoshikawa Miho , Takeuchi Mio , Zhang Ming 
Published: April 2017

Understanding the spatial distribution of Dehalococcoides and its reductive dehalogenase genes in sediment is important for bioremediation of sites contaminated with chlorinated ethylenes. A total of 56 sediment samples were collected from four contaminated sites in Japan, and quantified copies of Dehalococcoides 16S rRNA and reductive dehalogenase genes: tceA, bvcA, and vcrA, as well as chlorinated ethylenes. Dehalococcoides was detected from 22 sediment samples with various geological formations, textures and saturation conditions. The detected Dehalococcoides 16S rRNA gene ranged from 6.4 × 102 to 2.5 × 107 copies g−1. In the 22 samples, the dehalogenase genes: tceA, bvcA, and vcrA were contained 1.4 × 103 to 1.6 × 104, 1.0 × 103 to 2.0 × 105, and 2.7 × 102 to 8.5 × 105 copies g−1, respectively. Statistical analysis revealed that the distribution of dehalogenase genes depends on site and depth, but not existence of vinyl chloride. To estimate potential for bioremediation of contaminated sites, quantification of dehalogenase genes according to sediment depth is important and thus recommended.
Comparing Renewable Energy Policies in E.U.15, U.S. and China: A Bayesian DSGE Model
Authors: Argentiero Amedeo , Atalla Tarek , Bigerna Simona , Micheli Silvia , Polinori Paolo 
Published: April 2017

ABSTRACT The promotion of renewable energy sources (RES) by governments is one way of helping countries to meet their energy needs while lowering greenhouse gas emissions. In this paper, we examine the role of energy policy in RES promotion, based on a carbon tax and RES price subsidy, at a time of technological and demand shocks in the European Union (E.U.) 15 countries, the United States (U.S.) and China, focusing on the macroeconomic implications. Using a dynamic stochastic general equilibrium model for RES and fossil fuels, our results suggest that, in the presence of a total factor productivity shock in the fossil fuel sector, such an energy policy can also be a driving force for smoothing the reduction of RES in the energy market (and vice versa). Additionally, we show that the E.U.15 grouping has a comparative advantage in terms of reaching grid parity compared with the other countries we considered which are more fossil fuel dependent.