bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histological Changes in Alveolar Bone After Onlay Augmentation Using the Casing Method
Authors: Maruyama Kiichi , Ogiso Makoto , Mineno Seiji , Ono Wataru , Izumi Yuichi 
Published: January 2018

ABSTRACTNumerous studies on alveolar bone augmentation have been reported. However, it remains challenging to obtain favorable new bone, especially for onlay bone augmentation. For successful onlay bone augmentation, it is necessary to use a graft material with high bone‐forming activity and wound stabilization. We performed onlay bone augmentation on the buccal surface of mandibular alveolar bone in dogs, using a polyethylene terephthalate (PET) case (Casing method). The aim of this study was to histologically examine the feasibility of Casing method for external onlay bone augmentation. Beagle dogs were selected for this study. At 12 weeks after tooth extraction, a PET case was placed on the buccal surface of mandibular alveolar bone and filled with a mixture of hydroxyapatite and β‐tricalcium phosphate (β‐TCP) particles (volume ratio 1:1) impregnated with crushed autogenous bone (superfine bone powder) suspended in plasma. At 4, 8, and 16 weeks after bone graft, nondecalcified sections were histologically examined. At 4 weeks, new bone formation on the particle surfaces was observed on the original bone side of the PET case. At 16 weeks, bone formation was observed in almost all areas inside the case. The percentage of the augmented area (including new bone and particles surrounded by new bone; was significantly greater at 16 weeks (85.7% ± 6.0%) than at 4 weeks (10.5% ± 4.8%) or 8 weeks (69.6% ± 15.6%). The results of this study suggest that onlay bone augmentation using the Casing method has considerable potential to yield histologically favorable new bone formation. Anat Rec, 301:1148–1158, 2018. © 2018 Wiley Periodicals, Inc.
A Cross‐coupling Control Approach for Coordinated Formation of Surface Vessels with Uncertain Disturbances
Authors: Fu Mingyu , Yu Lingling , Wang Yuanhui , Jiao Jianfang 
Published: January 2018

AbstractIn this paper, a cross‐coupling control approach for the coordinated formation of multiple marine surface vessels with direct communication topology in the presence of model uncertainties and external disturbances is presented. To synchronize the vessels' relative position errors while tracking their assigned trajectories, a cross‐coupling formation controller is designed, in which a sliding mode surface in terms of the velocity tracking error and position cross‐coupling error is introduced. Then, an adaptive radial basis function neural network is incorporated into the controller to learn the upper bound of model uncertainties and external disturbances. Utilizing Barbalat's lemma and topology theory, all of the error signals in the closed‐loop system are proved to converge to zero asymptotically. Finally, numerical simulation results are provided to demonstrate the effectiveness of the proposed coordinated formation control strategy.
Fabrication of silver chloride nanoparticles using a plant serine protease in combination with photoactivation and investigation of their biological activities
Authors: Siritapetawee Jaruwan , Limphirat Wanwisa , Nantapong Nawarat , Songthamwat Dujdow 
Published: January 2018

AbstractRecently, the development of "green" methods for fabrication of silver nanoparticles (Ag‐NPs) has been emphasized, in view of their environmental safety, feasibility, and low cost. In this study, a serine protease, EuP‐82 from Euphorbia cf. lactea latex, was used to fabricate silver chloride nanoparticles (AgCl‐NPs) in phosphate‐buffered saline (pH 7.2), under the influence of visible light. The fabricated nanoparticles had a maximal surface plasmon resonance absorption peak at 435 nm. The size of the AgCl‐NPs, estimated by scanning electron microscopy, was 57 ± 14.7 nm. Energy dispersive X‐ray spectroscopy, X‐ray absorption spectroscopy, and X‐ray diffraction analysis confirmed that the fabricated Ag‐NPs were of the AgCl type. The fabricated nanoparticles had antioxidant activity, scavenging DPPH (2,2‐diphenyl‐1‐picrylhydrazyl) radicals with IC50 of 204 ± 1.8 μg/mL. The fabricated AgCl‐NPs had broad‐spectrum in vitro antimicrobial activities, acting against the Gram‐positive bacteria Staphylococcus aureus, methicillin‐resistant S. aureus (MRSA), and Bacillus cereus, and the Gram‐negative bacteria Escherichia coli and Pseudomonas aeruginosa. AgCl‐NPs also showed antifungal activity against Candida albicans and C. tropicalis. In addition, AgCl‐NPs showed antiprotozoal activity against Giardia lamblia, with IC50 202 ± 2.1 μg/mL. Based on the biological activities of the fabricated AgCl‐NPs, they have the potential for widespread application in medicine and industry.
Rechnerische und experimentelle Bestimmung der Tragfähigkeit eines Fensterbefestigers
Authors: Becker Rainer , Scheller Eckehard , Küenzlen Jürgen 
Published: January 2018

AbstractDie Fenstermontage in Mauerwerk, insbesondere in Lochsteinen mit dünnen Stegen und/oder Dämmstoff‐Füllungen, ist in den vergangenen Jahren zu einer anspruchsvollen Aufgabe geworden, für die eine vorherige statische Bemessung empfohlen wird. Für die Bemessung eines modernen Fensterbefestigers wurde ein auf Versuchen basierendes Rechenmodell entwickelt, auf deren Grundlage eine Zulassung erteilt wurde.
Transubclavian approach: A competitive access for transcatheter aortic valve implantation as compared to transfemoral
Authors: Amat‐Santos Ignacio J. , Rojas Paol , Gutiérrez Hipólito , Vera Silvio , Castrodeza Javier , Tobar Javier , Goncalves‐Ramirez L. Renier , Carrasco Manuel , Catala Pablo , San Román José A. 
Published: January 2018

AbstractAimsEmpirically, transfemoral (TF) approach is the first choice for transcatheter aortic valve implantation (TAVI). We aimed to investigate whether transubclavian (TSc) and TF approaches present comparable major outcomes according to current evidence.MethodsWe systematically searched PubMed, EMBASE, and Cochrane database for studies with symptomatic aortic stenosis patients who underwent TAVI through TF or TSc/axillary access from January/2006 to January/2017. Searched terms were: (“aortic stenosis” OR “transcatheter aortic” OR “TAVI” OR “TAVR”) and (“transfemoral” OR “transaxillary” OR “transubclavian”). Major outcomes according to Valve Academic Research Consortium‐2 criteria were gathered. The odds ratio (OR) was used as a summary statistic. A random‐effects model was used. A fully percutaneous TSc TAVI case from our institution illustrates minimalist approach.ResultsFinal analysis was made with six studies including 4,504 patients (3,886 TF and 618 TSc). Baseline characteristics of compared groups in individual studies were similar, with the exception of a higher logistic EuroSCORE in the TSc group (23.7 ± 1.92 vs. 21.17 ± 3.51, P = 0.04) and higher prevalence of coronary and peripheral artery disease with OR = 0.67 [95% CI: 0.54–0.83] (P = 0.0003) and OR = 0.08 [95% CI: 0.05–0.12] (P < 0.00001), respectively. TSc group presented comparable 30‐day mortality (OR = 1.37; [95%CI: 0.85–2.21]; P = 0.20). There were no differences for procedural success, 30‐day stroke rate, need for new pacemaker implantation, major vascular complications, and acute kidney injury requiring dialysis. Also, no differences were found concerning 1‐year mortality.ConclusionsOur study suggests that TSc approach may be, not only an alternative route to TF approach for TAVI, but even a competitive one in certain patients with increased risk of femoral injury.
Palladium‐Loaded Cucurbit[7]uril‐Modified Iron Oxide Nanoparticles for C−C Cross‐Coupling Reactions
Authors: Benyettou Farah , Motte Laurence , Traboulsi Hassan , Mazher Javed , Pasricha Renu , Olsen John‐Carl , Trabolsi Ali , Guenin Erwan 
Published: January 2018

AbstractCucurbit[7]uril modified iron oxide nanoparticles (CB[7]NPs) were loaded with palladium to form nano‐catalysts (Pd@CB[7]NPs) that, with microwave heating, catalysed Suzuki–Miyaura, Sonogashira, and Mizoroki–Heck cross‐coupling reactions. Reactions were run in environmentally benign 1:1 ethanol/water solvent under convenient aerobic conditions. In a preliminary screening, conversions and yields were uniformly high with turn over frequencies (TOF) ranging from 64 to 7360 h−1. The nano‐catalysts could be recovered with a magnet and reused several times (6 times for Suzuki–Miayura reaction) without loss of activity.
Spectroscopic Studies on Photoinduced Reactions of the Anticancer Prodrug, trans,trans,trans‐[Pt(N3)2(OH)2(py)2]
Authors: Vernooij Robbin R. , Joshi Tanmaya , Horbury Michael D. , Graham Bim , Izgorodina Ekaterina I. , Stavros Vasilios G. , Sadler Peter J. , Spiccia Leone , Wood Bayden R. 
Published: January 2018

AbstractThe photodecomposition mechanism of trans,trans,trans‐[Pt(N3)2(OH)2(py)2] (1, py=pyridine), an anticancer prodrug candidate, was probed using complementary Attenuated Total Reflection Fourier Transform Infrared (ATR‐FTIR), transient electronic absorption, and UV/Vis spectroscopy. Data fitting using Principal Component Analysis (PCA) and Multi‐Curve Resolution Alternating Least Squares, suggests the formation of a trans‐[Pt(N3)(py)2(OH/H2O)] intermediate and trans‐[Pt(py)2(OH/H2O)2] as the final product upon 420 nm irradiation of 1 in water. Rapid disappearance of the hydroxido ligand stretching vibration upon irradiation is correlated with a −10 cm−1 shift to the antisymmetric azido vibration, suggesting a possible second intermediate. Experimental proof of subsequent dissociation of azido ligands from platinum is presented, in which at least one hydroxyl radical is formed in the reduction of PtIV to PtII. Additionally, the photoinduced reaction of 1 with the nucleotide 5′‐guanosine monophosphate (5′‐GMP) was comprehensively studied, and the identity of key photoproducts was assigned with the help of ATR‐FTIR spectroscopy, mass spectrometry, and density functional theory calculations. The identification of marker bands for some of these photoproducts (e.g., trans‐[Pt(N3)(py)2(5′‐GMP)] and trans‐[Pt(py)2(5′‐GMP)2]) will aid elucidation of the chemical and biological mechanism of anticancer action of 1. In general, these studies demonstrate the potential of vibrational spectroscopic techniques as promising tools for studying such metal complexes.
Olefin‐Stabilized Cobalt Nanoparticles for C=C, C=O, and C=N Hydrogenations
Authors: Sandl Sebastian , Schwarzhuber Felix , Pöllath Simon , Zweck Josef , Jacobi von Wangelin Axel 
Published: January 2018

AbstractThe development of cobalt catalysts that combine easy accessibility and high selectivity constitutes a promising approach to the replacement of noble‐metal catalysts in hydrogenation reactions. This report introduces a user‐friendly protocol that avoids complex ligands, hazardous reductants, special reaction conditions, and the formation of highly unstable pre‐catalysts. Reduction of CoBr2 with LiEt3BH in the presence of alkenes led to the formation of hydrogenation catalysts that effected clean conversions of alkenes, carbonyls, imines, and heteroarenes at mild conditions (3 mol % cat., 2–10 bar H2, 20–80 °C). Poisoning studies and nanoparticle characterization by TEM, EDX, and DLS supported the notion of a heterotopic catalysis mechanism.
Luminescence Thermochromism of Gold(I) Phosphane–Iodide Complexes: A Rule or an Exception?
Authors: Glebko Nina , Dau Thuy Minh , Melnikov Alexei S. , Grachova Elena V. , Solovyev Igor V. , Belyaev Andrey , Karttunen Antti J. , Koshevoy Igor O. 
Published: January 2018

AbstractA series of gold(I) iodide complexes 1–11 have been prepared from di‐, tri‐, and tetraphosphane ligands. Crystallographic studies reveal that the di‐ (1–7) and tetrametallic (11) compounds feature linearly coordinated gold(I) ions with short aurophilic contacts. Their luminescence behavior is determined by the combined influence of the phosphane properties, metal–metal interaction, and intermolecular lattice‐defined interactions. The proposed variable contribution of 3(X+M)‐centered (X=halogen; M=metal) and 3XLCT (halogen to ligand charge transfer) electronic transitions into the lowest lying excited state, which is influenced by supramolecular packing, is presumably responsible for the alteration of room‐temperature emission color from green (λ=545 nm, for 11) to near‐IR (λ=698 nm, for 2). Dinuclear compounds 6 and 7 exhibit distinct luminescence thermochromism with a blueshift up to 5750 cm−1 upon cooling. Such dramatic change of emission energy is assigned to the presence of two coupled triplet excited states of 3ππ* and 3(X+M)C/3XLCT nature, the presence of which depends on both molecular structure and the crystal lattice arrangement.
Resveratrol Radical Repair by Vitamin C at the Micelle–Water Interface: Unexpected Reaction Rates Explained by Ion–Dipole Interactions
Authors: Kerzig Christoph , Hoffmann Matthias , Goez Martin 
Published: January 2018

AbstractRepair reactions of lipophilic phenoxy radicals by hydrophilic co‐antioxidants at model membranes are important for understanding the factors that govern the interactions between radical scavengers in biological systems. By using near‐UV photoionization, we have selectively generated the phenoxy radical of the famous antioxidant resveratrol inside anionic (SDS), cationic (DTAC), or neutral (TX‐100) micelles, as well as in homogeneous aqueous solution, and have compared its repairs in these media by the water‐soluble co‐antioxidants ascorbic acid and ascorbate monoanion. With all surfactants, these reactions are dynamic processes at the micelle–water interface. Whereas for the combinations ascorbate monoanion/ ionic micelle the repair rates can be rationalized by the Coulombic interactions, unexpected effects were observed with the neutral ascorbic acid and the charged micelles: for the anionic micelles, this repair is three times faster than in homogeneous solution, and two orders of magnitude faster than for the cationic micelles. Given that the repair by a concerted proton–electron transfer demands a coplanar arrangement of the resveratrol phenoxy centre sticking out into the Stern layer and the co‐antioxidant hydroxy moiety approaching from the aqueous bulk, we explain these results by ion–dipole interactions: only at a negatively charged micellar surface does the direction of the large dipole moment of ascorbic acid lead to an orientation favourable for the repair.
Infrared Multiphoton Dissociation Spectroscopy with Free‐Electron Lasers: On the Road from Small Molecules to Biomolecules
Authors: Jašíková Lucie , Roithová Jana 
Published: January 2018

AbstractInfrared multiphoton dissociation (IRMPD) spectroscopy is commonly used to determine the structure of isolated, mass‐selected ions in the gas phase. This method has been widely used since it became available at free‐electron laser (FEL) user facilities. Thus, in this Minireview, we examine the use of IRMPD/FEL spectroscopy for investigating ions derived from small molecules, metal complexes, organometallic compounds and biorelevant ions. Furthermore, we outline new applications of IRMPD spectroscopy to study biomolecules.
Synthesis of PEGylated Semiconducting Polymer Amphiphiles for Molecular Photoacoustic Imaging and Guided Therapy
Authors: Xie Chen , Cheng Penghui , Pu Kanyi 
Published: January 2018

AbstractSemiconducting polymer nanoparticles (SPNs) have been used as a new class of photonic materials with great potential in biomedical applications, but their synthetic method is limited to nanoprecipitation. Semiconducting polymer amphiphiles (SPAs) that can spontaneously self‐assemble into nanoparticles are ideal alternatives for SPNs. Depending on their backbone structures, SPAs with different optical properties can be developed into nanoprobes for molecular imaging applications such as photoacoustic (PA) and fluorescence imaging as well as photothermal therapy. In this Concept, recent studies on the synthesis of SPAs for PA imaging and guided cancer therapy are summarized. The effect of grafting density on the optical properties of SPAs is discussed, and the nanoparticle sizes of SPAs can be reduced by utilization of a short semiconducting oligomer. Moreover, SPAs can be developed into PA theranostic platform and activatable PA nanoprobes. These studies demonstrate that SPAs are promising for advanced molecular imaging and therapy applications.
Preparation of Chiral Contiguous Epoxyaziridines and Their Regioselective Ring‐Opening for Drug Syntheses
Authors: Mao Hui , Jeong Hyeonsu , Yang Jieun , Ha Hyun‐Joon , Yang Jung Woon 
Published: January 2018

AbstractSynthetically valuable chiral (aziridin‐2‐yl)oxirane‐3‐carbaldehydes bearing three consecutive functional groups including aziridine, epoxide, and aldehyde were prepared from the stereoselective epoxidation of (aziridin‐2‐yl)acrylaldehydes with H2O2 using organocatalyst (2R)‐ or (2S)‐[diphenyl(trimethylsilyloxy)methyl]pyrrolidine as organocatalyst. The regioselective ring opening of aziridines and epoxides enabled us to achieve the highly efficient asymmetric synthesis of the antibiotic edeine D fragment 3‐hydroxy‐4,5‐diaminopenatanoic acid, an intermediate for the formal synthesis of non‐proteinogenic amino acid (−)‐galantinic acid, and for potent antifungal agent (+)‐preussin, and the medicinally important framework 3‐hydroxy‐2‐hydroxymethylpyrrolidine.
Kinetics of the esterification between lactic acid and isoamyl alcohol in the presence of silica gel‐supported sodium hydrogen sulphate
Authors: Jiang Zhongkai , Xu Jumei , Zeng Zuoxiang , Xue Weilan , Li Shating 
Published: January 2018

AbstractThe esterification reaction between isoamyl alcohol and lactic acid was studied over silica gel‐supported sodium hydrogen sulphate (NaHSO4 · Silica). The influences of the external mass transfer, internal mass transfer, reaction temperature, catalyst loading, and initial reactant molar ratio were investigated. Kinetic experimental data of this esterification reaction obtained at different temperatures (343–378 K) were correlated with three models (the pseudo‐homogeneous (PH), Eley‐Rideal (ER), and Langmuir‐Hinshelwood (LH) model). The UNIFAC method was employed to estimate the activity coefficients when the non‐ideal thermodynamic behaviour of the reaction mixture was considered. The results show that the ER model is more appropriate for predicting the dynamic data of an esterification reaction. It was found that water and isoamyl alcohol were more strongly adsorbed onto the surface of NaHSO4 · Silica than lactic acid and isoamyl lactate, by comparing the adsorption equilibrium constants of different components existing in the reaction. The activation energy and standard enthalpy of the reaction were found to be 54.1 and −6.27 kJ mol−1, respectively.
Mapping the distribution of language related genes FoxP1, FoxP2, and CntnaP2 in the brains of vocal learning bat species
Authors: Rodenas‐Cuadrado Pedro M. , Mengede Janine , Baas Laura , Devanna Paolo , Schmid Tobias A. , Yartsev Michael , Firzlaff Uwe , Vernes Sonja C. 
Published: January 2018

AbstractGenes including FOXP2, FOXP1, and CNTNAP2, have been implicated in human speech and language phenotypes, pointing to a role in the development of normal language‐related circuitry in the brain. Although speech and language are unique to humans a comparative approach is possible by addressing language‐relevant traits in animal systems. One such trait, vocal learning, represents an essential component of human spoken language, and is shared by cetaceans, pinnipeds, elephants, some birds and bats. Given their vocal learning abilities, gregarious nature, and reliance on vocalizations for social communication and navigation, bats represent an intriguing mammalian system in which to explore language‐relevant genes. We used immunohistochemistry to detail the distribution of FoxP2, FoxP1, and Cntnap2 proteins, accompanied by detailed cytoarchitectural histology in the brains of two vocal learning bat species; Phyllostomus discolor and Rousettus aegyptiacus. We show widespread expression of these genes, similar to what has been previously observed in other species, including humans. A striking difference was observed in the adult P. discolor bat, which showed low levels of FoxP2 expression in the cortex that contrasted with patterns found in rodents and nonhuman primates. We created an online, open‐access database within which all data can be browsed, searched, and high resolution images viewed to single cell resolution. The data presented herein reveal regions of interest in the bat brain and provide new opportunities to address the role of these language‐related genes in complex vocal‐motor and vocal learning behaviors in a mammalian model system.
Optimization of pressurized liquid extraction by response surface methodology of Goji berry (Lycium barbarum L.) phenolic bioactive compounds
Authors: Tripodo Giusy , Ibáñez Elena , Cifuentes Alejandro , Gilbert‐López Bienvenida , Fanali Chiara 
Published: January 2018

AbstractPressurized liquid extraction (PLE) has been used for the first time in this work to extract phenolic compounds from Goji berries according to a multilevel factorial design using response surface methodology. The global yield (% w/dw, weight/dry‐weight), total phenolic content (TPC), total flavonoid (TF) and antioxidant activity (determined via ABTS assay, expressed as TEAC value) were used as response variables to study the effects of temperature (50–180°C) and green solvent composition (mixtures of ethanol/water). Phenolic compounds characterization was performed by high performance liquid chromatography–diode array detector–tandem mass spectrometry (HPLC‐DAD‐MS/MS). The optimum PLE conditions predicted by the model were as follows: 180°C and 86% ethanol in water with a good desirability value of 0.815. The predicted conditions were confirmed experimentally and once the experimental design was validated for commercial fruit samples, the PLE extraction of phenolic compounds from three different varieties of fruit samples (Selvatico mongolo, Bigol, and Polonia) was performed. Nine phenolic compounds were tentatively identified in these extracts, including phenolic acids and their derivatives, and flavonols. The optimized PLE conditions were compared to a conventional solid‐liquid extraction, demonstrating that PLE is a useful alternative to extract phenolic compounds from Goji berry.
Information theory measures for the engineering validation of ground‐motion simulations
Authors: Tsioulou Alexandra , Galasso Carmine 
Published: January 2018

SummaryThis short communication introduces a quantitative approach for the engineering validation of ground‐motion simulations based on information theory concepts and statistical hypothesis testing. Specifically, we use the Kullback‐Leibler divergence to measure the similarity of the probability distributions of recorded and simulated ground‐motion intensity measures (IMs). We demonstrate the application of the proposed validation approach to ground‐motion simulations computed by using a variety of methods, including Graves and Pitarka hybrid broadband, the deterministic composite source model, and a stochastic white noise finite‐fault model. Ground‐motion IMs, acting as proxies for the (nonlinear) seismic response of more complex engineered systems, are considered herein to validate the considered ground‐motion simulation methods. The list of considered IMs includes both spectral‐shape and duration‐related proxies, shown to be the optimal IMs in several probabilistic seismic demand models of different structural types, within the framework of performance‐based earthquake engineering. The proposed validation exercise (1) can highlight the similarities and differences between simulated and recorded ground motions for a given simulation method and/or (2) allow the ranking of the performance of alternative simulation methods. The similarities between records and simulations should provide confidence in using the simulation method for engineering applications, while the discrepancies should help in improving the tested method for the generation of synthetic records.