bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel tetra hybrid bio-nanofluid model with stenosed artery
Authors: Al-Kouz Wael , Shah Syed Zahir Hussain , Souayeh Basma , Sabir Zulqurnain , Owhaib Wahib 
Published: October 2024

Abstract
For treating and diagnosing cardiovascular diseases, the field of biomedical engineering is significant because it develops new ways and techniques. Stenosis is the narrowing of an artery, and it leads reduction in the flow rate of blood. This study investigates the blood flow mechanism in an artery using a mathematical model of Carreau nanofluid with four distinct nanoparticles. Tetra nanofluid model produces significant advancement in the simulation of blood flow through the stenosed arteries. The model is capable of predicting the pressure drop and velocity distribution for diagnosing and treating stenosis. The spectral relaxation approach is used to present the model's efficiency and effectiveness, which makes it a suitable method for solving the governing equations of this study. The findings of this study have important implications for the development of new treatments and diagnostic techniques for stenosis and other cardiovascular diseases.
Understanding the Incongruent Brand Personalities on Social Media: Evidence from Indian Brands
Authors: Vallabhajosula Anand , Daruri Venkata Srinivas Kumar 
Published: October 2024

Abstract
Although the social media websites decreased the firms’ control over their brand personalities, there is little research on the incongruence between communicated and perceived brand personality of Indian service brands. The impact of bots and suspicious accounts on the online brand personalities also remained unexplored. We analyzed 58,024 tweets of nine Indian service brands using machine learning. Some of the newer brands are savvier in managing their brand personalities. The public sector brands have poorer alignment between communicated and perceived brand personalities. A counterintuitive finding is that the brand sentiment changes in value, but not in category, after removing the suspicious accounts.
Old Vilnius in the Perspektive of Nations' Historical Consciousness
Authors: Bumblauskas Alfredas 
Published: October 2024

The article deals with the newest historiography on the analyses of Vilnius history through the use of multiperspective methodology (Multiperspektivität). The history of Vilnius (14th-16th c.) due to its multiethnic, multicultural, and multiconfessional aspects suits this methodological reflection since it does not seek to find "objective" monoview or to equalise the relief of historical identities but, on the contrary, to discover concepts and subjects which can reveal the variety of historical consciousness or even help in their formation. Theses - capital of Lithuania, Vilnius is a multiethnic and multicultural city, is banal and does not need to be proved. Although there is no such insight in the current historiography. On the one hand, the status of Vilnius as a capital was argued because of its multiethnicity; on the other hand, the question of multiculture was often neglected by stressing Polish, Russian, or Byelorussian heritage and thus participating in the political partition of Vilnius. The main tendencies of the different development of historical perspectives. Nowadays, changes in the model of cultural history of Lithuania could be found: from baltophilical (S. Daukantas) and lithuanocentric (A. Šapoka) concepts towards the concept of Lithuania's Europeanisation formulated by E. Gudavičius and research of J. Bardach signifying the independence of Lithuania at the end of the 18th century. We also could discuss new preconditions for the perspectives of historical consciousness of Lithuanian Poles (for example: introduction of the Polish-speaking nobility into the 19th-century Lithuanian society, theory of Europeanisation). These premises allow us to form insights on the perspective of Lithuanian Poles' historical consciousness. The reality of Lithuanian Russians' and Ukrainians' historical consciousness forms an insight that correct scientific historiographical bases have to be developed for the research on identities of the ethnic groups mentioned above. The phenomenon of the Vilnius Jewish community brings Lithuanian capital into another higher trajectory of historical consciousness. Vilnius could be called "Northern Jerusalem" not only because of its phenomenal role in Jewish culture but also because it is very difficult to find so many nations and confessions living so close to each other as here at the end of the 20th century. In this context, Lithuanian capital appears as a sphere of gravitation and junction of several civilizations and also as the coexistence space of several confessions.
Moderasi Beragama Minoritas Muslim Internasional di Buffalo State University Perspektif Muhammad Abduh
Authors: Husna Mohammad Hayyi Syafwan , Muktafi Muktafi 
Published: October 2024

This research actually comes from the experience of researchers who were studying at Buffalo State University at that time. This campus is located in the city of Buffalo, which is a multicultural and multireligious city. This provides an opportunity for researchers to learn and interact with people from various religious backgrounds. This research answers two problem formulations. First, how is the religious moderation of international Muslim minorities at Buffalo State University? second, what is the analysis of religious moderation of the international Muslim minority at Buffalo State University from Muhammad Abduh’s perspective? This research uses a qualitative approach. Data collection was obtained using observation techniques and interviews with community members. This research found that first, religious moderation in this community is an attitude of tolerance between religious believers and openness to anyone in various activities held by the community. Second, this community’s attitude toward religious moderation is in accordance with the concept put forward by Muhammad Abduh, which is about the problems faced when experiencing discrimination from other religions. A calm attitude and not interfering in other people’s problems shows evidence that they have implemented religious moderation, also being neutral and not taking sides with any party is the attitude they apply in their daily lives.
Optimization stages of transjugular intrahepatic portosystemic shunt technique as a treatment method for portal hypertension complications
Authors: Garbuzenko D. V. 
Published: October 2024

Aim. To describe the milestones to optimize of the technique of transjugular intrahepatic portosystemic shunt.Materials and methods. The PubMed and Embase databases, the Web of Science platform, the Google Scholar retrieval system, the Cochrane Database of Systematic Reviews, the eLIBRARY.RU scientific electronic library, and the reference lists were used to search for articles. Articles corresponding to the aim of the review were selected for 1969-2023. The inclusion criteria were limited to technical solutions related to optimize of the technique of transjugular intrahepatic portosystemic shunt.Results. Innovative ideas, subsequent experimental studies and preliminary experience in liver cirrhosis patients contributed to the introduction of transjugular intrahepatic portosystemic shunt into clinical practice. At the moment, the main achievement to optimize of the technique of transjugular intrahepatic portosystemic shunt is progress in the qualitative characteristics of stents. The transition from bare metal stents to expandable polytetraﬂuoroethylene-covered stent graft made it possible to largely prevent shunt dysfunction. However, the issue of its optimal diameter, contributing to an effective reduction of portal pressure without the risk of developing hepatic encephalopathy, which is one of the most common complications of transjugular intrahepatic portosystemic shunt, remains relevant.Conclusion. Further to optimize of the technique of transjugular intrahepatic portosystemic shunt, as well as careful selection of patients based on cognitive indicators, nutritional status and assessment of liver function will reduce the incidence of hepatic encephalopathy and improve treatment results.
Immediate and distant results of liver and bile duct resections for portal cholangiocarcinoma in elderly and senile patients
Authors: Efanov M. G. , Tarakanov P. V. , Koroleva A. A. , Vankovich A. N. , Kovalenko D. E. , Fisenko D. V. , Tsvirkun V. V. 
Published: October 2024

Aim. Evaluation of surgical outcomes in elderly and senile patients with portal cholangiocarcinoma.Materials and methods. The immediate and long-term results of surgical treatment of 170 patients with portal cholangiocarcinoma performed in 2013–2023 were analyzed. A comparison of the outcomes in patients aged below 60, 60–74, and over 74 years old was carried out. Factors prognostically associated with a high risk of fatal outcome in elderly and senile patients were determined by multivariate logistic regression analysis.Results. The senile patient group was more likely to develop severe complications (p = 0.089) and had a higher 90-day mortality (p = 0.042). The combination of such factors as the Charlson comorbidity index, Comprehensive Risk Score (CRS), resection volume, and surgery duration showed high prognostic significance with respect to hospital mortality, with an area under the ROC curve (AUC) of 0.895 (p < 0.001). The overall and recurrence-free survival of patients did not differ among all age groups (p = 0.886).Conclusion. In the absence of appropriate patient selection based on risk factors, the surgical outcomes in senile patients deteriorate. When planning a surgical intervention in senile patients, attention should be paid to minimizing surgical trauma and surgery duration, especially in patients with a high comorbidity index.
What Do We Know Without the Catalog? Eliciting Prior Beliefs from Experts for Aftershock Models
Authors: Schneider Max , Guttorp Peter 
Published: October 2024

Abstract
Fitting parametric seismological models to earthquake catalogs often comes with numerical challenges, especially when catalogs are small. An alternative way to quantify parameter values for a seismic region is by eliciting expert opinions on the seismological characteristics that each parameter corresponds to. For instance, expert beliefs on aftershock patterns can be formulated into prior distributions for aftershock parameters, for example, for the epidemic-type aftershock sequence (ETAS) model. We illustrate such a method by not only eliciting priors for ETAS parameters for the Pacific Northwest (PNW), a subduction zone with a complex tectonic environment, but also a relatively small catalog. We compare these priors with those suggested by the ETAS literature for global subduction zones, discussing implications for aftershock forecasting for the PNW.
Znaczenie i rola kultury w nauczaniu Jana Pawła II w kontekście wybranych współczesnych jej ujęć
Authors: Król Jerzy 
Published: October 2024

W niniejszym artykule przypomniano niektóre współczesne ujęcia i istotę kultury – jej rozumienie, aby właściwie odczytać myśl zawartą w nauczaniu Jana Pawła II dotyczącą jej rozumienia, znaczenia i roli. W tym celu przedstawiono niektóre opinie na jej temat oraz odniesienia historyczne. Starano się przedstawić myśl Jana Pawła II w odniesieniu do tych koncepcji, a zwłaszcza do nauczania Soboru Watykańskiego II i magisterium Kościoła. W tym kontekście podjęto rozważania na temat misji ewangelizacyjnej i edukacyjnej prowadzonej przez Kościół. Edukacja ta w swoich początkach związana jest z kulturą starożytnej Grecji i tradycją judeochrześcijańską. Zwrócono uwagę na wychowawczą moc greckiej paidei, a następnie przedstawiono specyfikę myśli Jana Pawła II odnoszącej się do roli i zadań kultury.
Investigation of antioxidant properties and influence on activity of collagenase and elastase of selected raw herbal materials from traditional Eastern medicine
Authors: Lewandowska Julia , Zych Maria , Szałabska-Rąpała Katarzyna , Kaczmarczyk-Żebrowska Ilona 
Published: October 2024

WprowadzenieTradycyjna medycyna wschodnia (<i>traditional Eastern medicine</i> – TEM) zyskuje coraz większą popularność w wysokorozwiniętych krajach Zachodu jako alternatywna forma wspierania zdrowia i pielęgnacji ciała. Wiele ziół stosowanych w tej praktyce medycznej posiada działanie antyoksydacyjne, przeciwzapalne czy immunomodulujące. Proces starzenia się skóry może postępować wraz z wiekiem, kiedy stopniowo ubywa włókien kolagenowych i elastynowych. Nadmierna ekspozycja na promieniowanie UV, pociągająca za sobą wzrost produkcji wolnych rodników, prowadzi do uszkodzeń na poziomie molekularnym licznych struktur w organizmie i m.in. przyspieszenia starzenia się skóry.Materiał i metodyW naparach otrzymanych z surowców pozyskanych z <i>Gynostemma pentaphyllum</i>, <i>Tinospora cordifolia</i>, <i>Astragalus membranaceus</i>, <i>Codonopsis pilosula</i>, <i>Asparagus racemosus</i> oraz <i>Ocimum sanctum</i> określono zawartość związków polifenolowych (m.in. kwasów fenolowych oraz flawonoidów), potencjał antyoksydacyjny (metodami ABTS, DPPH oraz FRAP), a także wpływ na aktywność enzymów – kolagenazy oraz elastazy.WynikiNajwyższą zawartość związków polifenolowych oraz najsilniejsze właściwości antyoksydacyjne obserwowano w naparach pozyskanych z ziela <i>O. sanctum</i>, natomiast największą zdolność do hamowania kolagenazy i elastazy wykazywały napary pozyskane z liści <i>T. cordifolia</i>.WnioskiNapary z <i>O. sanctum</i> i <i>T. cordifolia</i> mogą wykazywać potencjalnie korzystny wpływ na skórę, a także znaleźć zastosowanie w formulacjach stosowanych jako produkty przeciwstarzeniowe.
La actuación concurrencial de las personas jurídicas sin fines de lucro (y la libertad de realización de actividades económicas)
Authors: Pazos Hayashida Javier Mihail 
Published: October 2024

El presente trabajo analiza si las organizaciones sin fines de lucro pueden participar en actividades económicas no directamente relacionadas con objetivos altruistas o solidarios en el contexto legal peruano, así que se busca desafiar la percepción tradicional de que estas entidades deben limitarse a actividades benéficas.Se investiga la intersección entre el interés lucrativo y la actividad económica, destacando la autonomía privada que permite a estas organizaciones definir sus propios objetivos y actividades.En resumen, este estudio resalta cómo estas organizaciones contribuyen al desarrollo a través de su participación activa en el mercado, destacandosu papel integral en la economía y sociedad contemporánea.
¿Cómo se declara la nulidad manifiesta prevista en el artículo 220 del Código Civil? Una problemática de cuarenta años
Authors: Ninamancco Córdova Fort 
Published: October 2024

El artículo 220 del Código Civil permite al juez declarar de oficio la nulidad de un acto jurídico, pero solo si es ‘manifiesta’. Esta capacidad del juez ha generado dos interrogantes importantes: ¿qué pasos debe seguir el juez para declarar la nulidad de oficio? y ¿cómo se distingue una nulidad manifiesta de una no manifiesta?En esa línea, el autor del presente trabajo aborda la primera interrogante haciendo un análisis extenso de lo expuesto en distinta jurisprudencia (expedientes del Tribunal Constitucional y plenos casatorios).Sin embargo, hay un gran trabajo por delante en cuanto a la uniformización de la jurisprudencia, así como para alcanzar una correcta articulación entre esta y la doctrina.Así, el autor resalta la idea y la necesidad de encontrar un mecanismo de pasos para la declaración de nulidad que contemple los principios del debido proceso y a la vez sea restrictivo y eficiente frente a los usos de las partes.
Notas sobre la validez de los pactos prenupciales (y maritales)
Authors: Vega Mere Yuri 
Published: October 2024

En el Perú, persisten temores en torno a la reforma del libro de derecho de familia; luego de 40 años de vigencia del Código Civil de 1984, el autor persiste e incorpora nuevas razones para acceder a su ‘contractualización’ como reflejo de una sociedad que cada vez está menos dispuesta a contraer matrimonio.Estamos frente a una regulación que prolonga la crisis matrimonial y es contraproducente para el propio ordenamiento.El artículo se sirve de la experiencia norteamericana y de las iniciativas de la Uniform Law Commission o el American Law Institute para demostrarla complementariedad que puede existir entre la libertad de las partes al momento de celebrar acuerdos maritales o premaritales y el posterior escrutinio judicial. Se enfatiza que una modernización del derecho de familia no involucra la renunciar de los principios propios de la rama.
Sobre los contratos de ejecución continuada e instantánea: el tiempo y la satisfacción del interés del acreedor
Authors: Vargas Sequeiros Luis Diego , Ojeda Villamar Rafaela 
Published: October 2024

El presente artículo analiza la regulación nacional e internacional de los contratos de ejecución continuada e instantánea, destacando la naturaleza incompleta de dicha regulación y su impacto en la seguridad jurídica.Los autores proponen una clasificación basada en el papel del tiempo en la ejecución contractual y la satisfacción del interés del acreedor. Estos criterios se presentan como más precisos para diferenciar entre los contratos de ejecución continuada e instantánea, facilitando su aplicación práctica.
La mora del acreedor y el pago por consignación en el derecho del Perú y Argentina
Authors: Alferillo Pascual Eduardo 
Published: October 2024

El régimen de la ‘mora del acreedor’ y del ‘pago por consignación’ se estudia en el Código Civil del Perú y en el Código Civil y Comercial argentino, es posible así comparar los requisitos para la configuración, procedencia y efectos de cada una de estas figuras en la legislación vigente.Este método permite conocer la evolución del vínculo entre los institutos para visualizar las posibles soluciones que perfeccionen su armónico ensamble en el contexto de los 40 años aniversario del Código Civil del Perú.
The BET inhibitor sensitivity is associated with the expression level of CDC25B in pancreatic cancer models
Authors: Miller Aubrey L. , Garcia Patrick L. , Vance Rebecca B. , Heard Eric O. , Brown Eric J. , Yoon Karina J. 
Published: October 2024

Aim: Cell division cycle 25B (CDC25B) belongs to the CDC25 family of phosphatases that regulate cell cycle progression. CDC25B also contributes to tumor initiation and progression, but no connection between CDC25B levels and drug sensitivity in pancreatic cancer has been reported. Based on our finding that bromodomain and extraterminal domain (BET) inhibitors decrease levels of CDC25B, we aim to compare the sensitivity of models expressing contrasting levels of CDC25B to the BET inhibitor JQ1, in pancreatic cancer cell lines in vitro and in patient-derived xenograft (PDX) models of pancreatic ductal adenocarcinoma (PDAC) in vivo .
Methods: We compared the efficacy of the standard of care agent gemcitabine with the BET inhibitor JQ1, using alamarBlue assays to determine IC50s of three pancreatic cancer cell lines in vitro . We used immunohistochemistry (IHC) and immunoblot (IB) to detect CDC25B. We also compared the effect of each agent on the progression of PDX models of PDAC in vivo with contrasting levels of CDC25B.
Results: Immunohistochemical data demonstrated that levels of CDC25B differed by ~2- to 5-fold in cell lines and PDX models used. In vitro data showed that the level of CDC25B paralleled sensitivity to JQ1. Similarly, in vivo data showed that tumors with high-level CDC25B were more sensitive to JQ1 than tumors with lower CDC25B. The combination of JQ1 + a pan CDC25 inhibitor was synergistic in gemcitabine-resistant Panc1.gemR cells that had relatively high levels of CDC25B expression compared to parent cells.
Conclusion: The data suggest that CDC25B may be an independent indicator of sensitivity to BET inhibitors and that CDC25B may contribute to gemcitabine insensitivity in this tumor type.
Comparison of the quality of logistic regression models and a classification tree in predicting hospital mortality in elderly patients with non-ST-elevation myocardial infarction
Authors: Pereverzeva K. G. , Yakushin S. S. , Peregudova N. N. , Mishutina M. V. 
Published: October 2024

Aim. Using the CHAID (Chi Squared Automatic Interaction Detection) method to develop a classification tree for predicting hospital mortality in patients with non-ST-elevation myocardial infarction (non-STEMI) aged 75 years and older and compare the quality of the constructed model with the logistic regression model.Material and methods. A retrospective analysis of the case histories of 119 sequentially enrolled patients aged ≥75 years who were hospitalized in a cardiology department due to non-STEMI in 2020-2021 was carried out. The construction of a predictive model of probability of dying was carried out using the logistic regression method. To assess the impact of various predictors affecting the probability of dying during the of hospitalization period in patients with non-STEMI, a classification tree was developed using the CHAID method. To compare the quality of logistic regression models and the classification tree, the areas under the ROC curve and confidence intervals were estimated.Results. Based on the construction of a binary logistic regression, it was found that the factors increasing hospital mortality were cardiogenic shock (CS): odds ratio (OR) 47.55; 4.00-589.16; p=0.002; new-onset atrial fibrillation: OR 6.45; 1.39-30.42; p=0.018; and the number of points on the GRACE scale: for each increase by 1 point: OR 1.03; 1,00-1,05; p=0.046. Similar data were obtained when analyzing the classification tree: in patients with CS, the predicted mortality was 91.7%. The probability of an unfavorable outcome based on the constructed classification tree was higher than the average in the analyzed sample in persons without CS, 2-3 degree atrioventricular blocks, and pulmonary edema, but with right bundle branch block on the electrocardiogram (25.0%) and in persons without CS and atrioventricular blockages of 2-3 degrees, but with pulmonary edema and a Q wave on the electrocardiogram (50.0%). Both methods of predicting hospital mortality are applicable. There were no statistically significant differences in the quality of both constructed models; the difference in the areas under the ROC curves was 0.043±0.268 with a 95% confidence interval of -0.055-0.141, p=0.387.Conclusion. Both developed methods can be used to determine the probability of dying in a hospital. Currently, the recruitment of patients into a prospective study of a similar design has begun and is continuing, during which validation of the constructed forecasting models is planned.