bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geburtshilfliche Anästhesie: Altbewährtes, Kontroversen und neue Perspektiven – Teil 1
Authors: Kranke Peter , Annecke Thorsten , Bremerich Dorothee , Chappell Daniel , Girard Thierry , Gogarten Wiebke , Hanß Robert , Kaufner Lutz , Neuhaus Sophie , Ninke Tobias , Standl Thomas , Weber Stefan , Jelting Yvonne , Volk Thomas 
Published: October 2017

ZusammenfassungIn der „Whatʼs New in Obstetric Anesthesia“ Lecture, die jedem an der anästhesiologischen Kreißsaalversorgung Interessierten in abgedruckter Form sehr ans Herz gelegt werden kann, werden seit 1975 durch die Society for Obstetric Anesthesia and Perinatology die im Rahmen des Annual Meeting als relevant für die klinische Versorgung erachteten Vorträge zusammengefasst. Nach dem Tode von Gerard W. Ostheimer, Professor of Anesthesiology im Brigham and Womenʼs Hospital in Boston, Massachusetts, wurde sie zur Gerard W. Ostheimer „Whatʼs New in Obstetric Anesthesia“ Lecture umbenannt, um dessen Beiträge zur Regionalanästhesie und geburtshilflichen Anästhesie zu würdigen. Jedes Jahr gewährt die von ausgewählten Fachvertretern gehaltene Veranstaltung und ihr Abdruck in namhaften Anästhesie-Journalen Einblick in eine kritische Würdigung rezenter Literatur und die möglichen Konsequenzen für – aber nicht nur – die anästhesiologische Kreißsaalpraxis.Eine ähnliche Veranstaltung hat in Deutschland seit über 16 Jahren Tradition: Das Geburtshilfliche Anästhesiesymposium des Wissenschaftlichen Arbeitskreises Regionalanästhesie und Geburtshilfliche Anästhesie. Anders als in den von Einzelpersonen gehaltenen Vortragsveranstaltungen werden „Evergreens“ oder „Hot Topics“ der anästhesiologischen Kreißsaalversorgung in regelmäßigem Zyklus oder aus aktuellem Anlass aufgegriffen, präsentiert und vor allem diskutiert. In den Vortragsveranstaltungen offenbart sich oft wesentlich früher als in traditionellen Lehrbuchkapiteln der subtile Wandel in Hinblick auf die diskutierten Themen.Der 2-teilige Beitrag fasst das Symposium 2016 zusammen, stellt jedoch keine offizielle Meinungsbekundung seitens des Arbeitskreises dar. Teil 1 geht auf mütterliche Todesursachen während Schwangerschaft, Geburt und Stillzeit sowie strukturelle Voraussetzungen im Kreißsaal, Adipositas in der Schwangerschaft und Sepsis bei der Schwangeren und im Wochenbett ein. Teil 2 behandelt etablierte Standards und neue Perspektiven im Rahmen der geburtshilflichen Analgesie und Anästhesie bezüglich Epiduralanalgesie, postpunktionellem Kopfschmerz, Anästhesie und Analgesie während und nach Sectio, hämodynamischem Monitoring und postpartaler Blutung.
Die schweregradorientierte Therapie der Spondylodiszitis – eine prospektive Betrachtung anhand von elektronisch basierten Behandlungspfaden
Authors: Homagk Nadine , Jarmuzek Tina , Hofmann Gunther , Homagk Lars 
Published: October 2017

ZusammenfassungAnerkannte Behandlungsmethoden der Spondylodiszitis sind Ruhigstellung und systemische Antibiose. Allerdings ist die Datenlage für spezifische und weiterführende Behandlungsempfehlungen sehr heterogen. Ziel dieser Übersichtsarbeit ist die Therapieoptimierung der Spondylodiszitis anhand einer behandlungspfadorientierten Schweregradeinteilung im Konsens mit aktuellen Empfehlungen. Vom 1. 10. 1998 bis zum 31. 12. 2013 erfolgte die Etablierung einer Schweregradeinteilung mit spezifischen Therapieoptionen. Im Verlauf erfolgte die Anpassung der Schweregradeinteilung und die Entwicklung eines elektronisch basierten Behandlungspfads. Die schweregradorientierte Therapie der Spondylodiszitis anhand von elektronisch basierten Behandlungspfaden wurde prospektiv vom 01. 01. 2012 bis 31. 12. 2013 evaluiert. Insgesamt wurden 296 Fälle eingeschlossen. Bei einer stetig steigenden Fallzahl, zeigt sich auch ein zunehmendes Alter der Patienten bei Diagnosestellung mit einem Durchschnitt von 67,3 Jahren. Bei 34,3% dieser Patienten entwickelte sich die Spondylodiszitis spontan, und 68,6% der Patienten haben bis zu unserer Diagnosestellung keine Vorbehandlung erhalten. Im Rahmen der spezifischen Behandlung sank die Schmerzintensität von 6,0 auf 3,1 NRS (Numeric Rating Scale). Die Entzündungswerte fielen ebenfalls (CRP von 119,2 auf 46,7 mg/dl). Im Betrachtungszeitraum betrug die Zeit vom Symptombeginn bis zur operativen Versorgung 65,6 Tage und hat sich nicht wesentlich reduziert. Dennoch konnte die Zeit von der Aufnahme bis zur operativen Versorgung auf unter 3 Tage reduziert werden. Die Einteilung der Patienten in die 3 Schweregrade des Spondylodiscitis Severity Code (SSC) richtet sich nach dem SponDT „Spondylodiscitis Diagnosis and Treatment“, der bildmorphologisch beschriebenen knöchernen Wirbeldestruktion und dem aktuellen neurologischen Status und kann in einem elektronischen Behandlungspfad abgebildet werden. Dadurch lässt sich die Behandlung unter ökonomischer Ressourcennutzung optimieren und ihre sichere Dokumentation ist gewährleistet.
The Dutch translation of the Linguistic Inquiry and Word Count (LIWC) 2007 dictionary
Authors: Boot Peter , Zijlstra Hanna , Geenen Rinie 
Published: October 2017

Abstract
The words we use in everyday language reveal our thoughts, feelings, personality, and motivations. Linguistic Inquiry and Word Count (LIWC) is a software program to analyse text by counting words in 66 psychologically meaningful categories that are catalogued in a dictionary of words. This article presents the Dutch translation of the dictionary that is part of the LIWC 2007 version. It describes and explains the LIWC instrument and it compares the Dutch and English dictionaries on a corpus of parallel texts. The Dutch and English dictionaries were shown to give similar results in both languages, except for a small number of word categories. Correlations between word counts in the two languages were high to very high, while effect sizes of the differences between word counts were low to medium. The LIWC 2007 categories can now be used to analyse Dutch language texts.
The multilingual experience
Authors: Woll Nina 
Published: October 2017

AbstractOf the numerous factors affecting language development,a particular role has been assigned to Metalinguistic Awareness (MLA) as a major constituent of the cognitive development of experienced language learners, while being itself a key to accelerated language learning (e.g.,Jessner, 2008). The present study explores the relationship between multilingual usage and MLA in French-speaking Quebeckers (n = 66) with different language backgrounds who start to learn German after English in a formal setting. ‘Multilingual experience’ was operationalized by the frequency and the diversity of foreign language use across 10 different contexts of use. A reflexive dimension of MLA was assessed by means of the THAM-3 (Pinto & El Euch, 2015), and complemented by think-aloud protocols produced during a multilingual translation task, which reflected an applied dimension of MLA. Multiple regression analyses suggest that both frequency and diversity of non-native language use in specifically literacy-based activities predicted the applied dimension of MLA.
CLIFinder: identification of LINE-1 chimeric transcripts in RNA-seq data
Authors: Pinson Marie-Elisa , Pogorelcnik Romain , Court Franck , Arnaud Philippe , Vaurs-Barrière Catherine 
Published: October 2017

Abstract

Summary
L1 Chimeric Transcripts (LCTs) are initiated by repeated LINE-1 element antisense promoters and include the L1 5′UTR sequence in antisense orientation followed by the adjacent genomic region. LCTs have been characterized mainly using bioinformatics approaches to query dbEST. To take advantage of NGS data to unravel the transcriptome composition, we developed Chimeric LIne Finder (CLIFinder), a new bioinformatics tool. Using stranded paired-end RNA-seq data, we demonstrated that CLIFinder can identify genome-wide transcribed chimera sequences corresponding to potential LCTs. Moreover, CLIFinder can be adapted to study transcription from other repeat types.

Availability and implementation
The code is available at: https://github.com/GReD-Clermont/CLIFinder; and for Galaxy users, it is directly accessible in the tool shed at: https://toolshed.g2.bx.psu.edu/view/clifinder/clifinder/.

Supplementary information
Supplementary data are available at Bioinformatics online.
mORCA: sailing bioinformatics world with mobile devices
Authors: Díaz-del-Pino Sergio , Falgueras Juan , Perez-Wohlfeil Esteban , Trelles Oswaldo 
Published: October 2017

Abstract

Motivation
Nearly 10 years have passed since the first mobile apps appeared. Given the fact that bioinformatics is a web-based world and that mobile devices are endowed with web-browsers, it seemed natural that bioinformatics would transit from personal computers to mobile devices but nothing could be further from the truth. The transition demands new paradigms, designs and novel implementations.

Results
Throughout an in-depth analysis of requirements of existing bioinformatics applications we designed and deployed an easy-to-use web-based lightweight mobile client. Such client is able to browse, select, compose automatically interface parameters, invoke services and monitor the execution of Web Services using the service's metadata stored in catalogs or repositories.

Availability and implementation
mORCA is available at http://bitlab-es.com/morca/app as a web-app. It is also available in the App store by Apple and Play Store by Google. The software will be available for at least 2 years.

Supplementary information
Source code, final web-app, training material and documentation is available at http://bitlab-es.com/morca
Systematic Government Access to Private-Sector Data in Brazil
Authors: Magrani Bruno 
Published: October 2017

Abstract
This chapter describes the ways through which the Brazilian government may have access to personal data in possession of private-sector organizations with a specific focus on identifying the possibility of systematic access. There is no comprehensive data protection legislation in Brazil, but specific and sparse statutes regulate governmental access in areas such as telecommunications, wiretapping, financial data, money laundering, and national intelligence. There have been many conflicting decisions in the judiciary about governmental access to personal data, particularly registration data. In order to address this issue, a statute in 2012 expanded the investigative powers of the police and the Public Prosecutor’s Office, granting them access to registration data regardless of a court order. Brazil’s Internet Bill of Rights from 2014 aims to provide further clarity on some unresolved issues at the same time that it creates new ones.
Systematic Government Access to Private-Sector Data in China
Authors: Wang Zhizheng 
Published: October 2017

Abstract
This chapter focuses on China’s systematic government access to private-sector data. In accordance with facilitating Chinese e-government construction, many laws made for the purpose of state security, public security, censorship, and taxation have granted the Chinese government extensive power of access to private-sector data generated in such businesses as information, finance, trade, travel, entertainment, and so on, operated in China. There are no laws or practices related to governmental systematic access currently found in China. However, this kind of systematic data access will certainly find itself anytime in the future enforcement and ensuing legislation once the Chinese government realizes it is necessary with the evolution of e-government strategy.
Liberal development, 1925–46
Authors: Toye John 
Published: October 2017

Abstract
Keynes’s writings are often disregarded in the context of economic development, overlooking that Russia was a developing country in his lifetime. He wrote about the experimental economic techniques that the Soviet government employed. He visited Russia three times and wrote A Short View of Russia in which he explained and criticized Bolsheviks’ policy of export and import monopolies, an overvalued exchange rate, inflationary government finance, and the subsidization of industry. These were policies that many developing countries adopted after decolonization. Keynes’s conclusion was that they were inefficient and that ‘bourgeois economics was valid in a communist country’. Did Keynes change his mind in the 1930s? If anything, he grew more harshly critical of Soviet economic policies and carefully distinguished them from his own endorsement of moderate trade protection and government supplementary investment in times of depression.
Learning from Clinical Experience with Necrotizing Fasciitis: Treatment and Management
Authors: Liu Yukun , Guo Ke , Sun Jiaming 
Published: October 2017

GENERAL PURPOSE:
To provide information about necrotizing fasciitis (NF), how to recognize it, and evidence-based treatment.

TARGET AUDIENCE:
This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

LEARNING OBJECTIVES/OUTCOMES:
After completing this continuing education activity, you should be able to:

ABSTRACT
Necrotizing fasciitis is a threatening, rapidly progressive, infectious disease of the soft tissue. In this article, based on 3 cases, the authors aim to summarize the clinical experience of patients with necrotizing fasciitis and the current concepts of the treatment and management of this disease.
The Association between Tinea Pedis and Feet-Washing Behavior in Patients with Diabetes: A Cross-sectional Study
Authors: Takehara Kimie , Amemiya Ayumi , Mugita Yuko , Tsunemi Yuichiro , Seko Yoko , Ohashi Yumiko , Ueki Kohjiro , Kadowaki Takashi , Oe Makoto , Nagase Takashi , Ikeda Mari , Sanada Hiromi 
Published: October 2017

ABSTRACT

OBJECTIVES:
To examine the correlations between elements of feet-washing behavior, presence of tinea pedis (TP), and patients’ background characteristics in order to identify a concrete intervention method to prevent TP.

DESIGN AND PARTICIPANTS:
A cross-sectional study of 30 patients with diabetes (16 with TP) who were admitted to or visited the university hospital.

MAIN OUTCOME MEASURES:
The presence of TP was confirmed by the detection of dermatophytes by direct microscopy. Data on elements of feet-washing behavior, such as scrubbing between the toes, were collected by observing recorded videos of participants normally washing their feet as they do at home. The patients’ background characteristics included demographic data; diabetes-related factors; patient knowledge regarding diabetes, foot problems, and TP prevention; purpose for feet washing; and any difficulties in feet washing.

MAIN RESULTS:
The number of times patients scrubbed between their toes while washing with soap was significantly lower in patients with TP (odds ratio, 0.95; P = .036; with a cutoff value of 35 times) and those who had difficulty in reaching their feet with their hands (B = −14.42, P = .041).

CONCLUSIONS:
An effective foot-washing protocol should include specific instructions for patients to scrub between their toes at least 35 times in all 8 spaces while washing with soap. Appropriate advice is also needed for individuals who have difficulty reaching their feet with their hands. Education about appropriate foot-washing behavior may potentially prevent TP.
Medical-Grade Honey Dressing Use in Developing Countries
Authors: Winter George Frederick 
Published: October 2017

ABSTRACT
Compared with other medical honeys, SurgihoneyRO (H&R Healthcare Ltd, Southmoor, Abingdon, United Kingdom), a bioengineered medical-grade honey, delivers low concentrations of reactive oxygen to wounds over a sustained period. This article describes how one provider, Dr Jill Brooks, has successfully used this new antimicrobial dressing in Africa and examines the potential positive impact this dressing could have on wound care in developing countries.
Safety and Feasibility of Early Physical Therapy for Patients on Extracorporeal Membrane Oxygenator: University of Maryland Medical Center Experience*
Authors: Wells Chris L. , Forrester Jenny , Vogel Joshua , Rector Raymond , Tabatabai Ali , Herr Daniel 
Published: October 2017

Objectives:
To examine the feasibility and safety of mobilizing patients while on extracorporeal membranous oxygenation support.

Design:
Retrospective cohort study.

Setting:
Medical and Surgical ICUs in a large tertiary care hospital in the United States.

Patients:
Adults supported on extracorporeal membranous oxygenation from January 2014 to December 2015.

Measurements and Main Results:
We reviewed the medical records from physical therapy, perfusion, and intensivists to obtain the number and type of physical therapy interventions and discharge status; extracorporeal membranous oxygenation type and description of support, cannulation sites; and risk management details of adverse effects, if any. Of 254 patients supported on extracorporeal membranous oxygenation, 167 patients (66.7%) received a total of 607 physical therapy sessions while on extracorporeal membranous oxygenation support. In this cohort, 134 patients (80.2%) had at least one femoral cannula during physical therapy intervention. Sixty-six of the 167 patients (39.5%) were supported on extracorporeal membranous oxygenation with bifemoral cannulas, and 44 (26.3%) were on veno-arterial extracorporeal membranous oxygenation. A dual lumen catheter was only used in five cases. Twenty-five patients (15%) (13 bifemoral cases) participated in standing or ambulation activities. Seventy-five patients (68.8%) who were successfully weaned from extracorporeal membranous oxygenation were discharged to a rehabilitation facility; 26 patients (23.8%) went home. Three minor events (< 0.5%) involving two episodes of arrhythmias and a hypotension event interrupted the therapy sessions, but mobility activities and exercises resumed that day. No major events were reported.

Conclusions:
With a highly trained multidisciplinary team and a focus on restoring function, it is feasible and safe to deliver early rehabilitation including standing and ambulation to patients on extracorporeal membranous oxygenation support even those with femoral cannulation sites with veno-arterial extracorporeal membranous oxygenation and veno-venous extracorporeal membranous oxygenation.
Integrated Hepatitis C Testing and Linkage to Care at a Local Health Department Sexually Transmitted Disease Clinic: Determining Essential Resources and Evaluating Outcomes
Authors: Rhea Sarah , Seña Arlene C. , Hilton Alison , Hurt Christopher B. , Wohl David , Fleischauer Aaron 
Published: October 2017

Abstract
Guidance about integration of comprehensive hepatitis C virus (HCV)-related services in sexually transmitted disease (STD) clinics is limited. We evaluated a federally funded HCV testing and linkage-to-care program at an STD clinic in Durham County, North Carolina. During December 10, 2012, to March 31, 2015, the program tested 733 patients for HCV who reported 1 or more HCV risk factor; 81 (11%) were HCV-infected (ie, HCV antibody-positive and HCV ribonucleic acid-positive). Fifty-one infected patients (63%) were linked to care. We concluded that essential program resources include reflex HCV ribonucleic acid testing; a dedicated bridge counselor to provide test results, health education, and linkage-to-care assistance; and referral relationships for local HCV management and treatment.
Kidney Transplant Recipients With Primary Membranous Glomerulonephritis Have a Higher Risk of Acute Rejection Compared With Other Primary Glomerulonephritides
Authors: Singh Tripti , Astor Brad , Zhong Weixiong , Mandelbrot Didier , Djamali Arjang , Panzer Sarah 
Published: October 2017

Background
Despite being the leading cause of graft failure, there is a lack of published data about the rates of rejection in kidney transplant patients with glomerulonephritis as the cause of end-stage renal disease.

Methods
We examined all consecutive adult (>18 years) renal transplant recipients with biopsy-proven native renal glomerular disease who underwent kidney transplant between 1994 and 2013. Glomerulonephritis groups included were IgA nephropathy (IgAN) (N = 306), focal segmental glomerulosclerosis (FSGS) (N = 298), membranous nephropathy (MN) (N = 81), and lupus nephritis (LN) (N = 177).

Results
In the total cohort of 862 patients, 363 patients had an episode of acute rejection during the follow-up period of 19 years (incidence rate of 7.2% per year). Forty-five of 81 patients with MN had an episode of acute rejection during the follow-up period. Patients with MN had significantly higher incidence of acute rejection (12.1 per 100 person years, P < 0.05) in comparison to IgAN (7.2 per 100 person years), FSGS (7.4 per 100 person years), and LN (7.9 per 100 person years). Patients with MN had 1.9 times higher risk of developing acute rejection after transplant in comparison to IgAN (P < 0.005). In patients with MN, 33 of 45 (73.3%) rejection events were acute cellular rejection, 8 (17.8%) of 45 were acute antibody-mediated rejection and 6 of 45 (13.3%) were combined cellular and antibody-mediated acute rejection. Despite higher rates of acute rejection, 10-year allograft survival was similar in all subgroups.

Conclusions
Patients with MN have higher incidence of acute rejection after kidney transplant but have similar 10-year allograft survival in comparison to the other glomerular diseases like IgAN, FSGS, and LN.
Liver Transplantation From Donors With a History of Malignancy: A Single-Center Experience
Authors: Benkö Tamas , Hoyer Dieter P. , Saner Fuat H. , Treckmann Jürgen W. , Paul Andreas , Radunz Sonia 
Published: October 2017

Background
The demand for transplantable organs exceeds donor organ supply. Transplantation of organs from donors with a history of malignancy remains controversial and the transmission of cancer in liver transplant recipients has not been sufficiently examined.

Methods
From 2002 until 2017, 83 livers from donors with a history of malignancy were transplanted at the University Hospital Essen, Germany. Donor and recipient data, type of malignancy, tumor-free interval at organ procurement, and follow-up data were analyzed.

Results
Nine different tumor sites (central nervous system [n = 27], genitourinary [n = 24], breast [n = 10], skin [n = 8], colorectal [n = 5], lung [n = 3], hemato-oncological [n = 3], thyroid [n = 2], and larynx [n = 1]) were detected in 83 donors. The majority (58%) of donors had tumor-free intervals of less than 5 years versus 19% of 6 to 10 years versus 23% over 10 years. The risk of tumor transmission from donors was assessed as low in 44 (53%), intermediate in 28 (34%), and high in 11 (13%) cases. During median follow-up of 19.9 (0-155) months, none of the recipients developed donor-transmitted malignancy.

Conclusions
Liver transplantation with organs from donors with a medical history of malignancy is feasible, and the risk of donor-transmitted malignancy appears to be low in this single-center analysis. A careful selection of donors remains mandatory and can expand the donor pool.