bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feeding twin-bearing Merino ewes above the metabolisable energy requirements for maintenance during late gestation increases the duration of parturition of the first-born lamb
Authors: Munn Amy L. , van Wettere William H. E. J. , Swinbourne Alyce M. F. , Weaver Alice C. 
Published: October 2024

Context In Australia, approximately 53% of lamb deaths are caused by dystocia. One of the main welfare concerns in the sheep industry is under- and overfeeding ewes, which may be contributing to cases of dystocia. Aims This pilot study aimed to investigate how increasing energy intake affects the duration of parturition and predictors of lamb survival. Methods On Day 100 of gestation (dG), 20 twin-bearing and 10 singleton Merino ewes were selected and allocated to three treatment groups; (1) singleton ewes fed at 1.0× maintenance levels (n = 10); (2) twin-bearing ewes fed at 1.0× maintenance levels (n = 10) or (3) twin-bearing ewes fed at 1.25× maintenance (n = 10). Ewes were housed indoors in individual pens. Urine and blood were sampled from ewes on dG 130, 140, then daily from dG 145 through to parturition, and blood was sampled at the onset of parturition and 30 min post-partum. Urine was analysed for pH and blood was analysed for metabolic parameters, mineral concentration and acid–base balance. Predictors of lamb survival from birth to 24 h consisted of weight, rectal temperature, blood glucose and lactate, and body morphology. Key results Serum calcium in late gestation and blood base excess pre-parturition were higher in Singletons 1M compared with Twins 1M (P < 0.05). The Twins 1.25M group took longer to give birth to the first-born lamb (104.4 ± 21.1 min) compared with the Twins 1M group (44.1 ± 6.6 min; P = 0.015). There were no differences in the predictors of lamb survival measures between the twin-bearing groups (P > 0.05). Conclusions Ewes from the Twins 1.25M group took significantly longer to give birth to the first-born lamb. There were no other significant findings between the twin-bearing groups, including lamb liveweight, however, lambs born to ewes from the Twins 1.25 group were numerically heavier, which may explain the increase in parturition length. Implications Feeding ewes above maintenance did not provide any production benefits to metabolic health or any other physiological parameters. Producers should avoid overfeeding ewes during late gestation.
Hydrogen halides HBr/DBr/TBr and HI/DI/TI: Born-Oppenheimer rovibrational spectrum
Authors: Aguilar-Díaz Daniel , Olivares-Pilón Horacio 
Published: October 2024

Abstract
The full bound rovibrational spectra

E

(
ν
,
L
)

for the ground electronic state

X

1

Σ
+

of the hydrogen bromine HBr and hydrogen iodine HI is calculated in the Born-Oppenheimer approximation. As a starting point an analytical expression for the potential energy curve V(R), valid in the entire domain

R
∈
[
0
,
∞
)

, is obtained in the form of a two-point Padé approximant that correctly reproduces the asymptotic behavior for small

R
→
0

and large

R
→
∞

internuclear distances. Remaining free parameters are fixed by making a fit with the experimental RKR points. In a second stage, the rovibrational spectra

E

(
ν
,
L
)

is obtained by solving the nuclear Schröodinger equation with nuclear interaction V(R). It was found that the potential energy curve for the ground electronic state

X
1

Σ
+

supports a total of 798/748 rovibrational states with maximal vibrational/rotational quantum numbers

v

max

=
19

/

17

and

L

max

=
65

/

66

for hydrogen halides HBr/HI, respectively. Through a simple modification in the nuclear Schröodinger equation, the bound rovibrational spectra

E

(
ν
,
L
)

is obtained for the isotopological species with deuterium (D) and tritium (T) content: DBr/TBr (1575/2329 states in total with

ν

max

=
27

/

34

and

L

max

=
92

/

112

) and DI/TI (1485/2207 states in total with

ν

max

=
25

/

31

and

L

max

=
93

/

114

).
Extracting terrain elevation information in front of the vehicle based on vehicle-mounted LiDAR in dynamic environments
Authors: Xu Peng , Liu Shuang , Zhao Dingxuan , Wu Xiaoyang , Lin Zhenjun , Zhang Cong 
Published: October 2024

Abstract
Point cloud maps constructed using 3D LiDAR, are widely used for robot navigation and localization. Few studies have utilized point cloud maps to extract terrain elevationinformation in front of a vehicle, which can be used as active suspension inputs to reduce vehicle bumps. In addition, the trajectories of dynamic objects in point cloud maps and global navigation satellite system (GNSS) data loss can affect the extraction of elevation information. To solve these problems, this paper proposes a framework for extracting terrain elevation information in front of the vehicle based on vehicle-mounted LiDAR in dynamic environments. The framework consists of two modules: point cloud map construction and vehicle front terrain elevation information extraction. In the point cloud map construction module, a system for simultaneous localization and mapping (SLAM) is proposed, which is capable of building point cloud maps without GNSS. Furthermore, a dynamic descriptor-based dynamic object filtering algorithm is proposed which is applied to SLAM. Therefore, the SLAM system overcomes the influence of dynamic objects on vehicle position and attitude estimation, and there are no trajectories of dynamic objects in the point cloud maps built by the system. In the vehicle front terrain elevation information extraction module, the unscented Kalman filter is utilized to predict the vehicle position at the next moment. Based on the geometric features of the tire-ground contact area, the terrain elevation information of the tire contact area at the predicted position on the point cloud map is extracted. Experiments show that the algorithm in this paper overcomes the effect of dynamic objects and builds a vehicle point cloud map without dynamic objects under GNSS data loss, which improves the accuracy of the extraction of terrain elevation information in front of the vehicle.
CMUT for ultrafast passive cavitation detection during ultrasound-induced blood–brain barrier disruption: proof of concept study
Authors: Cornu Corentin , Jourdain Laurène , Barcella Flavien , Colin Laurent , Edon Zoé , Dauba Ambre , Selingue Erwan , Gennisson Jean-Luc , Larrat Benoit , Certon Dominique , Novell Anthony 
Published: October 2024

Abstract

Objective. Cavitation dose monitoring plays a key role in ultrasound drug delivery to the brain. The use of capacitive micromachined ultrasonic transducer (CMUT) technology has a great potential for passive cavitation detection (PCD). Approach. Here, a circular (diameter 7 mm) CMUT centered at 5 MHz was designed to be inserted into a therapeutic transducer (1.5 MHz) used for ultrasound-induced blood–brain barrier (BBB) disruption on mice. CMUT-based real-time cavitation detection was performed during the ultrasound procedure (50 μl intravenous injection of SonoVue microbubbles, frequency 1.5 MHz, PNP 480 kPa, duty Cycle 10%, PRF 10 Hz, duration 60 s). BBB disruption were confirmed by contrast-enhanced 7T-MRI. Main results. The CMUT device has a fractional bandwidth of 140%, almost twice a conventional piezocomposite PCD transducer. As expected, the CMUT device was able to detect the occurrence of harmonic, subharmonic and ultraharmonic frequencies as well as the increase of broadband signal indicating inertial cavitation in a wide frequency range (from 0.75 to 6 MHz). Signal-to-noise ratio was high enough (>40 dB) to perform ultrafast monitoring and follow the subtle intrapulse variations of frequency components at a rate of 10 kHz. Significance. This first in vivo proof of concept demonstrates the interest of CMUT for PCD and encourages us to develop devices for PCD in larger animals by integrating an amplifier directly to the CMUT front-end to considerably increase the signal-to-noise ratio.
Expressibility-induced concentration of quantum neural tangent kernels
Authors: Yu Li-Wei , Li Weikang , Ye Qi , Lu Zhide , Han Zizhao , Deng Dong-Ling 
Published: October 2024

Abstract
Quantum tangent kernel methods provide an efficient approach to analyzing the performance of quantum machine learning models in the infinite-width limit, which is of crucial importance in designing appropriate circuit architectures for certain learning tasks. Recently, they have been adapted to describe the convergence rate of training errors in quantum neural networks in an analytical manner. Here, we study the connections between the expressibility and value concentration of quantum tangent kernel models. In particular, for global loss functions, we rigorously prove that high expressibility of both the global and local quantum encodings can lead to exponential concentration of quantum tangent kernel values to zero. Whereas for local loss functions, such issue of exponential concentration persists owing to the high expressibility, but can be partially mitigated. We further carry out extensive numerical simulations to support our analytical theories. Our discoveries unveil a fundamental feature of quantum neural tangent kernels, indicating that the issue of their concentration cannot be bypassed merely by transitioning to a local encoding scheme while maintaining high expressibility. This offers valuable insights for the design of wide quantum variational circuit models in practical applications.
Monte Carlo study of microdosimetric spectra conversion from diamond to tissue in proton therapy
Authors: Yu Songke , Bai Bing , Wang Dong , Zhong Xiaojuan , Chen Huamin 
Published: October 2024

Abstract
Diamond is regarded as a promising material in
microdosimetry. However, since the stopping power of the diamond is
different from tissue, the energy deposition distribution in the
diamond is not identical to that in tissue. Therefore, a conversion
of the spectra in the diamond microdosimeter to the tissue site is
needed. In this work, we introduced a method for the tissue
equivalence conversion of diamond microdosimeters, which is
developed to perform the energy deposition spectra conversion from
the diamond to an equivalent size of tissue in radiotherapy. It was
derived from the scaled Fourier transformation and the scaling
factor. The method was tested by comparing the spectra converted
from the diamond to tissue with those obtained in tissue along the
Bragg curve at different locations. The results show that: i) the
conversion method can overcome the defect of poor coincidence of the
spectra between converted and actual results in low deposition
energy zones, which is introduced by the method derived based on the
distribution characteristics; ii) The equivalence between detector
material and target tissue can affect the conversion results at the
plateau of the Bragg curve; iii) The inconsistency between the
converted and actual spectra due to the spectra shapes was also
found, which occurs in the range of η from 0.117 to 1.248 for
diamonds in this work; iv) the conversion at the distal part of the
Bragg peak should pay attention to the range of the incident
particles and the diamond microdosimeter size. To sum up, the method
introduced in this work shows relatively good results in
microdosimetric spectra conversion from diamond to tissue,
especially in low-energy deposition regions. Nonetheless, further
study is necessary to improve the practicability of this method so
that it can be competent for spectral conversion on the whole Bragg
curve.
Oxygen-functionalization of unique hierarchical carbon nanosheet fishtail-like for synergistically enhanced capacitive performance supercapacitor
Authors: Taer Erman , Nursyafni Nursyafni , Apriwandi Apriwandi , Fudholi Ahmad , Chitraningrum Nidya , Deraman Mohamad , Taslim Rika 
Published: October 2024

Abstract
The optimization of high-performance supercapacitors with enhanced electrochemical properties using biomass-based activated carbon is a challenging task. To overcome this, a novel strategy was used to create functional nanocarbon with a hierarchical-nanosheet structure based on bio-waste of Clausena Excavata Burm F (CEBF) leaves. The precursor was optimized through different chemical impregnation concentrations without the addition of any other substances. This resulted in a unique hierarchical carbon nanosheet fishtail-like with a specific surface area of 828.679 m2 g−1. The high carbon content of CEBF (up to 88.58%) and 4.46% oxygen as heteroatoms showed a beneficial pseudocapacitance effect. The electrochemical properties of CEBF-activated carbon were excellent, with a specific capacitance of 248 F g−1. The optimal energy density reached 33.8267 Wh kg−1, and the power density was 4.755 kW kg−1 at 10 A g−1. These findings suggest that CEBF biomass has significant potential as a source of hierarchical carbon nanosheet that enhances high-performance electrochemical supercapacitors.
Syntactic transitivity
Authors: Creissels Denis 
Published: October 2024

Abstract
The first section of this chapter discusses the articulation between semantic transitivity and syntactic transitivity. Section 3.2 surveys various types of alternations affecting the coding of agents and patients of prototypical transitive verbs and discusses the criteria according to which they can be analyzed in terms of either variants of the transitive construction, or intransitive alternatives to the transitive construction. Section 3.3 deals with the analysis of transitive constructions in which one of the terms (the pivot) is explicitly marked as the syntactically privileged term, and the selection of the pivot is independent of its possible characterization as A or P. Section 3.4 is devoted to semantically bivalent verbs that do not select the transitive construction as their coding frame. Section 3.5 discusses the possibility of evolutions by which a construction that was initially an intransitive alternative to the transitive construction becomes the basic construction of transitive verbs.
Flexivalency alternations
Authors: Creissels Denis 
Published: October 2024

Abstract
This chapter puts forward a typology of uncoded valency alternations. Section 15.1 clarifies problematic points about the notion of uncoded valency alternation and discusses terminological issues. Section 15.2 puts forward a typology of flexivalency alternations involving a change in transitivity (ambitransitivity). Sections 15.3 and 15.4 examine in more detail the two major subtypes of ambitransitivy: P-ambitransitivity and A-ambitransitivity. Section 15.5 is devoted to flexivalency alternations involving two intransitive constructions, and section 15.6 to flexivalency alternations involving two transitive constructions. Section 15.7 deals with the particular case of symmetrical verbs. Section 15.8 discusses flexivalency alternation involving impersonal constructions. Section 15.9 is about the particular case of avalent verbs. Section 15.10 discusses an atypical type of flexivalency alternation found in Bantu languages.
The Relationship Between 10-year Changes in Cognitive Ability and Subsequent Mortality: Findings from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) Trial
Authors: Chen Diefei , Gross Alden L , Parisi Jeanine M , Willis Sherry L , Felix Cynthia , Thorpe Roland J , Marsiske Michael , Thomas Kelsey R , Huang Alison R , Rebok George W 
Published: October 2024

Abstract
Cognitive ability and cognitive decline are related to mortality in older adults. Cognitive interventions have been found to improve cognitive performance and slow cognitive decline in later life. However, the longitudinal effects of cognitive interventions on mortality in older adults remain unclear. Using twenty-year follow-up data from the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) trial, we examined the association between cognitive trajectory (i.e., intercept, slope, and retest effect) and mortality, using shared growth-survival models. We evaluated the effect of ACTIVE cognitive training (memory, reasoning, and speed of processing) on mortality risk. Among the 2,802 participants, 2,021 died on or before the year 2019 (72.1%). Higher baseline, slower decline, and greater retest effects in general cognitive performance were associated with lower mortality risk after adjusting for covariates. Associations with mortality were similar contrasting general and domain-specific cognitive abilities. We did not observe any significant effects of ACTIVE cognitive training in memory, reasoning, or speed of processing on all-cause mortality. Our findings suggest cognitive training interventions do not have a significant effect on cognitive trajectory and mortality among older adults; rather, older adults with higher education tend to incur greater survival benefits from memory training.
Score Disclosure
Authors: Celik Levent , Drugov Mikhail 
Published: October 2024

Abstract
We study verifiable disclosure by a seller when the product has multiple quality attributes. We identify an equilibrium in which, for some qualities, the seller discloses its score—the average of the qualities—and does not reveal anything else. This occurs when its score is sufficiently high or when the qualities are sufficiently similar and the score is not too low. Otherwise, the seller fully discloses. While full unravelling is still an equilibrium, it is dominated by this partial score disclosure equilibrium in terms of ex ante as well as ex post profits.
N-glycoproteomic and proteomic alterations in SRD5A3-deficient fibroblasts
Authors: Garapati Kishore , Ranatunga Wasantha , Joshi Neha , Budhraja Rohit , Sabu Saniha , Kantautas Kristin A , Preston Graeme , Perlstein Ethan O , Kozicz Tamas , Morava Eva , Pandey Akhilesh 
Published: October 2024

Abstract
SRD5A3-CDG is a congenital disorder of glycosylation (CDG) resulting from pathogenic variants in SRD5A3 and follows an autosomal recessive inheritance pattern. The enzyme encoded by SRD5A3, polyprenal reductase, plays a crucial role in synthesizing lipid precursors essential for N-linked glycosylation. Despite insights from functional studies into its enzymatic function, there remains a gap in understanding global changes in patient cells. We sought to identify N-glycoproteomic and proteomic signatures specific to SRD5A3-CDG, potentially aiding in biomarker discovery and advancing our understanding of disease mechanisms. Using tandem mass tag (TMT)-based relative quantitation, we analyzed fibroblasts derived from five patients along with control fibroblasts. N-glycoproteomics analysis by liquid chromatography–tandem mass spectrometry (LC–MS/MS) identified 3,047 glycopeptides with 544 unique N-glycosylation sites from 276 glycoproteins. Of these, 418 glycopeptides showed statistically significant changes with 379 glycopeptides decreased (P &lt; 0.05) in SRD5A3-CDG patient-derived samples. These included high mannose, complex and hybrid glycan-bearing glycopeptides. High mannose glycopeptides from protocadherin Fat 4 and integrin alpha-11 and complex glycopeptides from CD55 were among the most significantly decreased glycopeptides. Proteomics analysis led to the identification of 5,933 proteins, of which 873 proteins showed statistically significant changes. Decreased proteins included cell surface glycoproteins, various mitochondrial protein populations and proteins involved in the N-glycosylation pathway. Lysosomal proteins such as N-acetylglucosamine-6-sulfatase and procathepsin-L also showed reduced levels of phosphorylated mannose-containing glycopeptides. Our findings point to disruptions in glycosylation pathways as well as energy metabolism and lysosomal functions in SRD5A3-CDG, providing clues to improved understanding and management of patients with this disorder.
Interactions that define the arrangement of sugar-binding sites in BDCA-2 and dectin-2 dimers
Authors: Liu Yu , Kim Jong-Won , Feinberg Hadar , Cull Nikeel , Weis William I , Taylor Maureen E , Drickamer Kurt 
Published: October 2024

Abstract
The sugar-binding receptors dectin-2 and blood dendritic cell antigen 2 (BDCA-2) bind oligosaccharide ligands through extracellular carbohydrate-recognition domains (CRDs) and initiate intracellular signaling through Fc receptor γ adapters (FcRγ). Dectin-2 stimulates macrophages in response to pathogen binding while BDCA-2 modulates cytokine production in plasmacytoid dendritic cells. The oligomeric states of these receptors and the orientations of their CRDs have been investigated by analysis of a naturally occurring disulfide-bonded variant of BDCA-2 and by replacement of transmembrane domains with N-terminal dimerization domains to create extracellular domain dimers of both dectin-2 and BDCA-2. Analysis of these constructs, as well as previously described crystal structures of the CRDs from these proteins and a novel structure of an extended version of the extracellular domain of dectin-2, showed that there is only limited interaction of the CRDs in the dimers, but interactions can be stabilized by the presence of the neck region. The resulting orientation of sugar-binding sites in the dimers would favor crosslinking of multiple dimers by oligosaccharide ligands, causing clustering of FcRγ to initiate signaling.
Moderate hypothermia circulatory arrest as a brain-protective strategy for type A aortic dissection
Authors: Wakisaka Hodaka , Miwa Shunta , Matsubayashi Yuji , Mori Yotaro , Lee Junghun , Kamiya Kenichi , Takashima Noriyuki , Suzuki Tomoaki 
Published: October 2024

Abstract

OBJECTIVES
Brain-protective strategies for acute type A aortic dissection (TAAD) remain controversial. Moderate hypothermia circulatory arrest (MHCA) without cerebral perfusion is not commonly used. However, we aimed to assess its safety and efficacy in 358 patients who underwent hemiarch replacement with MHCA for acute type A aortic dissection at our institution from August 2012 to August 2022.

METHODS
Clinical outcomes were compared according to circulatory arrest time [≤15 min (S group, n = 52) vs ≥16 min (L group, n = 306)]. The primary outcome was postoperative stroke.

RESULTS
The S group had more older patients (72.5 vs 68.8 years; P = 0.04), a greater incidence of carotid artery malperfusion (21% vs 11%; P = 0.043) and a lower body mass index (21.7 vs 23.6 kg/m2; P &lt; 0.01) and hemodynamic instability (3.8% vs 16%; P = 0.02) than the L group. The incidence of postoperative stroke (7.7% vs 12%; P = 0.33) and the rate of 30-day mortality (5.8% vs 6.5%; P = 0.83) did not significantly differ between groups. After adjusting for all potential confounding factors pre- and intraoperatively, there was no significant difference in postoperative outcomes between groups.

CONCLUSIONS
MHCA alone for TAAD had comparable postoperative outcomes with circulatory arrest times under and over 15 min. However, longer arrest times were associated with a higher risk of stroke.