bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Access to the 2H‐Tetrahydro‐4,6‐dioxo‐1,2‐oxazine Ring System from Nitrone via a Tandem Nucleophilic Addition and Transesterification Reaction.
Authors: Yang Shaoqiang , Liao Daohong , Tian Xiaoqi , Lei Xiaoguang 
Published: June 2016

AbstractThe first general route to the title oxazine ring system, a heterocyclic scaffold found in the complex natural products alchivemycin A and B, is given.
ChemInform Abstract: Efficient and Convenient Synthesis, Characterization, and Antimicrobial Evaluation of Some New Tetracyclic 1,4‐Benzothiazines.
Authors: Mor Satbir , Nagoria Savita 
Published: June 2016

AbstractAmong the tested tetracyclic 1,4‐benzothiazines (III), compounds (IIIg) and (IIIh) are found to be more potent than the standard drugs against A.
ChemInform Abstract: Multicomponent Synthesis of Cyclic Depsipeptide Mimics by Ugi Reaction Including Cyclic Hemiacetals Derived from Asymmetric Organocatalysis.
Authors: de la Torre Alexander F. , Rivera Daniel G. , Concepcion Odette , Echemendia Radell , Correa Arlene G. , Paixao Marcio W. 
Published: June 2016

AbstractPolysubstituted nine‐membered‐ring lactones are prepared by Ugi reaction of enantiomerically enriched cyclic hemiacetals with a wide range of α‐amino acids and isocyanides of aliphatic, peptidic, glycosidic, and lipidic nature.
ChemInform Abstract: Copper‐Catalyzed Borylation of Cyclic Sulfamidates: Access to Enantiomerically Pure (β‐and γ‐Aminoalkyl)boronic Esters.
Authors: Ursinyova Nina , Bedford Robin B. , Gallagher Timothy 
Published: June 2016

AbstractIt is proposed, that a N‐sulfated iodide is the key intermediate in the borylation reaction of cyclic sulfonamides.
ChemInform Abstract: TBAI‐Catalyzed Oxidative C—H Functionalization: A New Route to Benzo[b]phosphole Oxides.
Authors: Zhang Yun , Hu Gaobo , Ma Dumei , Xu Pengxiang , Gao Yuxing , Zhao Yufen 
Published: June 2016

AbstractThe first simple and efficient TBAI‐catalyzed addition/cyclization of toluene derivatives with diaryl(arylethynyl)phosphine oxides, furnishing rapid access to a structurally diverse array of benzo[b]phosphole oxides via sequential Csp3—H/Csp2—H functionalization with remarkable functional group tolerance and good to excellent yields is developed.
ChemInform Abstract: Room‐Temperature Alkynylation of Phosphine Oxides with Copper Acetylides: Practical Synthesis of Alkynylphosphine Oxides.
Authors: Gerard Phideline , Veillard Romain , Alayrac Carole , Gaumont Annie‐Claude , Evano Gwilherm 
Published: June 2016

AbstractUpon simple activation with molecular oxygen at room temperature copper acetylides are shown to be convenient reagents for the alkynylation of sencondary phosphine oxides.
ChemInform Abstract: Enantioselective Total Synthesis of the Proposed Structure of the Endophytic Fungal Metabolite Phomolide G: Structural Revision and Unambiguous Stereochemical Assignment.
Authors: McNulty James , McLeod David , Jenkins Hilary A. 
Published: June 2016

AbstractThe synthesis of the proposed structure of phomolide G (I) from L‐tartaric acid shows significant differences in the NMR data with the natural product.
ChemInform Abstract: Cipacinoids A—D, Four Limonoids with Spirocyclic Skeletons from Cipadessa cinerascens.
Authors: Yu Jin‐Hai , Liu Qun‐Fang , Sheng Li , Wang Guo‐Cai , Li Jia , Yue Jian‐Min 
Published: June 2016

AbstractCipacinoids A (I) shows moderate protein tyrosine phosphatase 1B inhibition.
ChemInform Abstract: New Perspectives in Organolanthanide Chemistry from Redox to Bond Metathesis: Insights from Theory
Authors: Kefalidis Christos E. , Castro Ludovic , Perrin Lionel , Rosal Iker Del , Maron Laurent 
Published: June 2016

AbstractReview: [a fifteen year contribution of computation studies in close synergy with experiments; 262 refs.
ChemInform Abstract: High‐Valent‐Cobalt‐Catalyzed C—H Functionalization Based on Concerted Metalation—Deprotonation and Single‐Electron‐Transfer Mechanisms
Authors: Wei Donghui , Zhu Xinju , Niu Jun‐Long , Song Mao‐Ping 
Published: June 2016

AbstractReview: [61 refs.
ChemInform Abstract: Quinoxaline‐Based Scaffolds Targeting Tyrosine Kinases and Their Potential Anticancer Activity
Authors: El Newahie Aliya M. S. , Ismail Nasser S. M. , Abou El Ella Dalal A. , Abouzid Khaled A. M. 
Published: June 2016

AbstractReview: 116 refs.
Combinatorial Library Screening Coupled to Mass Spectrometry to Identify Valuable Cyclic Peptides
Authors: Camperi Silvia A. , Giudicessi Silvana L. , Martínez‐Ceron María C. , Gurevich‐Messina Juan M. , Saavedra Soledad L. , Acosta Gerardo , Cascone Osvaldo , Erra‐Balsells Rosa , Albericio Fernando 
Published: June 2016

AbstractCombinatorial library screening coupled to mass spectrometry (MS) analysis is a practical approach to identify useful peptides. Cyclic peptides can have high biological activity, selectivity, and affinity for target proteins, and high stability against proteolytic degradation. Here we describe two strategies to prepare combinatorial libraries suitable for MS analysis to accelerate the discovery of cyclic peptide structures. Both approaches use ChemMatrix resin and the linker 4‐hydroxymethylbenzoic acid. One strategy involves the synthesis of a one‐bead–two‐peptides library in which each bead contains both the cyclic peptide and its linear counterpart to facilitate MS analysis. The other protocol is based on the synthesis of a cyclic depsipeptide library in which a glycolamidic ester group is incorporated by adding glycolic acid. After library screening, the ring is opened and the peptide is released simultaneously for subsequent MS analysis. © 2016 by John Wiley & Sons, Inc.
Using Time‐Dependent Density Functional Theory to Probe the Nature of Donor–Acceptor Stenhouse Adduct Photochromes
Authors: Laurent Adèle D. , Medveď Miroslav , Jacquemin Denis 
Published: June 2016

AbstractThe front cover artwork is provided by University of Nantes (France) and Matel Bel University in Banská Bystrica (Slovakia). The image shows the vibrationally‐resolved spectra of the open DASA isomer. Read the full text of the article at 10.1002/cphc.201600041.
Structural and Theoretical Study of Salts of the [B9H14]− Ion: Isolation of Multiple Isomers and Implications for Energy Storage
Authors: Kelley Steven P. , McCrary Parker D. , Flores Luis , Garner Edward B. , Dixon David A. , Rogers Robin D. 
Published: June 2016

AbstractBoranes and boron hydrides are well known for their novel molecular structures and useful chemical reactivity, with [B9H14]− notable in particular for its ease of isolation, unusual structure, and tautomerization. We report an experimental and theoretical investigation of the structure of [B9H14]− and the energetics of some of its reactions. Salts of [B9H14]− with 1‐ethyl‐3‐methylimidazolium and N‐butyl‐N‐methylpyrrolidinium were characterized by single‐crystal X‐ray diffraction and demonstrate the stabilization of an isomer of [B9H14]− not previously observed in the solid state. Heats of formation and acid dissociation constants of [B9H14]− and closely related structures were calculated. The results suggest a mechanism for particularly energetic hypergolic ignition induced by protonation and suggest potential for reversible H2 storage. These results encourage further investigation of [B9H14]− as an energy‐storage medium in ionic systems.
Mammalian Cell Tissue Culture Techniques
Authors: Phelan Katy , May Kristin M. 
Published: June 2016

AbstractCultured tissues and cells are used extensively in physiological and pharmacological studies. In vitro cultures provide a means of examining cells and tissues without the complex interactions that would be present if the whole organism were studied. A number of special skills are required in order to preserve the structure, function, behavior, and biology of cells in culture. This unit describes the basic skills required to maintain and preserve cell cultures: maintaining aseptic technique, preparing media with the appropriate characteristics, passaging, freezing and storage, recovering frozen stocks, and counting viable cells. © 2016 by John Wiley & Sons, Inc.
Combining Optimized Particle Morphology with a Niobium‐Based Coating for Long Cycling‐Life, High‐Voltage Lithium‐Ion Batteries
Authors: Gabrielli Giulio , Axmann Peter , Diemant Thomas , Behm Rolf Jürgen , Wohlfahrt‐Mehrens Margret 
Published: June 2016

AbstractMorphologically optimized LiNi0.5Mn1.5O4 (LMNO‐0) particles were treated with LiNbO3 to prepare a homogeneously coated material (LMNO‐Nb) as cathode in batteries. Graphite/LMNO‐Nb full cells present a twofold higher cycling life than cells assembled using uncoated LMNO‐0 (graphite/LMNO‐0 cell): Graphite/LMNO‐0 cells achieve 80 % of the initial capacity after more than 300 cycles whereas for graphite/LMNO‐Nb cells this is the case for more than 600 cycles. Impedance spectroscopy measurements reveal significantly lower film and charge‐transfer resistances for graphite/LMNO‐Nb cells than for graphite/LMNO‐0 cells during cycling. Reduced resistances suggest slower aging related to film thickening and increase of charge‐transfer resistances when using LMNO‐Nb cathodes. Tests at 45 °C confirm the good electrochemical performance of the investigated graphite/LMNO cells while the cycling stability of full cells is considerably lowered under these conditions.
Electrochemically Produced Graphene for Microporous Layers in Fuel Cells
Authors: Najafabadi Amin Taheri , Leeuwner Magrieta J. , Wilkinson David P. , Gyenge Előd L. 
Published: June 2016

AbstractThe microporous layer (MPL) is a key cathodic component in proton exchange membrane fuel cells owing to its beneficial influence on two‐phase mass transfer. However, its performance is highly dependent on material properties such as morphology, porous structure, and electrical resistance. To improve water management and performance, electrochemically exfoliated graphene (EGN) microsheets are considered as an alternative to the conventional carbon black (CB) MPLs. The EGN‐based MPLs decrease the kinetic overpotential and the Ohmic potential loss, whereas the addition of CB to form a composite EGN+CB MPL improves the mass‐transport limiting current density drastically. This is reflected by increases of approximately 30 and 70 % in peak power densities at 100 % relative humidity (RH) compared with those for CB‐ and EGN‐only MPLs, respectively. The composite EGN+CB MPL also retains the superior performance at a cathode RH of 20 %, whereas the CB MPL shows significant performance loss.
Photo‐reduction of CO2 Using a Rhenium Complex Covalently Supported on a Graphene/TiO2 Composite
Authors: Cui Shi‐Cong , Sun Xue‐Zhong , Liu Jin‐Gang 
Published: June 2016

AbstractOne of the promising solutions for decreasing atmospheric CO2 is artificial photosynthesis, in which CO2 can be photoconverted into solar fuels. In this study, a rhenium complex Re(PyBn)(CO)3Cl (PyBn=1‐(2‐picolyl)‐4‐phenyl‐1H‐1,2,3‐triazole) was covalently grafted onto the surface of reduced graphene oxide (rGO). This was further combined with TiO2 to fabricate a novel catalyst composite TiO2–rGO–Re(PyBn)(CO)3Cl for CO2 photo‐reduction. This hybrid composite demonstrated high selectivity conversion of CO2 into CO under xenon‐lamp irradiation. Compared with the unsupported homogeneous catalyst Re(PyBn)(CO)3Cl, the covalent immobilized catalyst composite TiO2–rGO–Re(PyBn)(CO)3Cl enhanced the turnover number six times and significantly improved catalyst stability. During the process of CO2 photo‐reduction, intermediate species with lifetimes longer than hundreds of microseconds were observed and the formation of CO products was revealed using timeresolved infrared spectroscopy. A plausible mechanism for CO2 photo‐reduction by the TiO2–rGO–Re(PyBn)(CO)3Cl catalyst composite has been suggested. The obtained results have implications for the future design of efficient catalyst composites for CO2 photo‐conversion.
Microclimate modification by riparian vegetation affects the structure and resource limitation of arthropod communities
Authors: Allen Daniel C. 
Published: June 2016

AbstractGround and surface water hydrology often governs the abundance and type of vegetation present in dryland riparian ecosystems, particularly along rivers that have both perennial and intermittent reaches. But how these differences in riparian vegetation affect riparian arthropod communities is not well understood. I conducted a replicated field experiment at three sites along the San Pedro River in central Arizona, United States, which varied in ground and surface water hydrology and in riparian vegetation. The most mesic site was comprised of cottonwood‐willow gallery forest and had more canopy cover, higher absolute humidity, and lower maximum air temperature than the most arid site, which was comprised of mesquite and saltcedar scrubland. Experimental treatments added resources (water, sugar, and a no resource control) to assess water and energy limitation of ground‐dwelling arthropods over a 4‐week period. I found that arthropod community structure differed between the three study sites, and that these changes were strongly associated with differences in microclimate. The most mesic site had 5.5 times greater arthropod biomass than the most arid site. I also found that the effect size of water supplementation on cricket abundance and the effect size of sugar supplementation on ant abundance were related to microclimate variables. Water effects on cricket abundance were larger, and sugar effects on ant abundance smaller, as general aridity increased. However, I found no relationship between the magnitude of water or sugar effects on total arthropod community abundance and microclimate variables. Nevertheless, these results indicate that groundwater depth can indirectly affect the abundance, community structure, and water vs. energy limitation of riparian arthropod communities via groundwater effects on riparian vegetation, and riparian vegetation effects on microclimate. Increases in river drying events due to climate change and increased water withdrawals will likely lead to changes in riparian vegetation in arid systems, and here I show that these changes could affect riparian animal communities as well.
Increases in mean annual temperature do not alter soil bacterial community structure in tropical montane wet forests
Authors: Selmants Paul C. , Adair Karen L. , Litton Creighton M. , Giardina Christian P. , Schwartz Egbert 
Published: June 2016

AbstractSoil bacteria play a key role in regulating terrestrial biogeochemical cycling and greenhouse gas fluxes across the soil‐atmosphere continuum. Despite their importance to ecosystem functioning, we lack a general understanding of how bacterial communities respond to climate change, especially in relatively understudied ecosystems like tropical montane wet forests. We used a well‐studied and highly constrained 5.2°C mean annual temperature (MAT) gradient in tropical montane wet forests on the Island of Hawaii to test the hypothesis that long‐term, whole‐ecosystem warming and the accompanying increase in belowground carbon flux increase the diversity and alter the composition of soil bacterial communities. Across this MAT gradient, dominant vegetation, substrate type and age, soil moisture, and disturbance history are constant, allowing us to effectively isolate the influence of rising MAT on soil bacterial community structure. Contrary to our hypothesis, we found that the richness, evenness, and phylogenetic diversity of the soil bacterial community remained remarkably stable with MAT and that MAT did not predict variation in bacterial community composition despite a substantial increase in belowground soil carbon fluxes across the gradient. Our results suggest that other factors that are constant across this gradient—such as soil pH, water availability and plant species composition—may be more important than warming in influencing soil bacterial community composition and diversity, at least within the temperature range studied here (~13–18°C MAT). Ours is the first study to demonstrate stability of soil bacterial community structure with rising MAT and increased belowground carbon flux in a tropical wet forest ecosystem. Moreover, our results add to growing evidence that the diversity and composition of soil bacterial communities dominated by Proteobacteria and Acidobacteria in low‐pH forest soils may be insensitive to the direct effect of climate warming.
Can the eastern red‐backed salamander (Plethodon cinereus) persist in an acidified landscape?
Authors: Bondi Cheryl A. , Beier Colin M. , Ducey Peter K. , Lawrence Gregory B. , Bailey Scott 
Published: June 2016

AbstractHardwood forests of eastern North America have experienced decades of acidic deposition, leading to soil acidification where base cation supply was insufficient to neutralize acid inputs. Negative impacts of soil acidity on amphibians include disrupted embryonic development, lower growth rates, and habitat loss. However, some amphibians exhibit intraspecific variation in acid tolerance, suggesting the potential for local adaptation in areas where soils are naturally acidic. The eastern red‐backed salamander (Plethodon cinereus) is a highly abundant top predator of the northern hardwood forest floor. Early research found that P. cinereus was sensitive to acidic soils, avoiding substrates with pH < 3.8 and experiencing decreased growth rates in acidic habitats. However, recent studies have documented P. cinereus populations in lower pH conditions than previously observed, suggesting some populations may persist in acidic conditions. Here, we evaluated relationships between organic horizon soil pH and P. cinereus abundance, adult health (body size and condition), and microhabitat selection, based on surveys of 34 hardwood forests in northeastern United States that encompass a regional soil pH gradient. We found no associations between soil pH and P. cinereus abundance or health, and observed that this salamander used substrates with pH similar to that available, suggesting that pH does not mediate their fine‐scale distributions. The strongest negative predictor of P. cinereus abundance was the presence of dusky salamanders (Desmognathus spp.), which were most abundant in the western Adirondacks. Our results indicate that P. cinereus occupies a wider range of soil pH than has been previously thought, which has implications for their functional role in forest food webs and nutrient cycles in acid‐impaired ecosystems. Tolerance of P. cinereus for more acidic habitats, including anthropogenically acidified forests, may be due to local adaptation in reproductively isolated populations and/or generalist life history traits that allow them to exploit a wider resource niche.
Assessing ecotoxicity of biomining effluents in stream ecosystems by in situ invertebrate bioassays: A case study in Talvivaara, Finland
Authors: Salmelin Johanna , Leppänen Matti T. , Karjalainen Anna K. , Vuori Kari-Matti , Gerhardt Almut , Hämäläinen Heikki 
Published: June 2016

Abstract

Mining of sulfide-rich pyritic ores produces acid mine drainage waters and has induced major ecological problems in aquatic ecosystems worldwide. Biomining utilizes microbes to extract metals from the ore, and it has been suggested as a new sustainable way to produce metals. However, little is known of the potential ecotoxicological effects of biomining. In the present study, biomining impacts were assessed using survival and behavioral responses of aquatic macroinvertebrates at in situ exposures in streams. The authors used an impedance conversion technique to measure quantitatively in situ behavioral responses of larvae of the regionally common mayfly, Heptagenia dalecarlica, to discharges from the Talvivaara mine (Sotkamo, Northern Finland), which uses a biomining technique. Behavioral responses measured in 3 mine-impacted streams were compared with those measured in 3 reference streams. In addition, 3-d survival of the mayfly larvae and the oligochaete Lumbriculus variegatus was measured in the study sites. Biomining impacts on stream water quality included increased concentrations of sulfur, sulfate, and metals, especially manganese, cadmium, zinc, sodium, and calcium. Survival of the invertebrates in the short term was not affected by the mine effluents. In contrast, apparent behavioral changes in mayfly larvae were detected, but these responses were not consistent among sites, which may reflect differing natural water chemistry of the study sites. Environ Toxicol Chem 2017;36:147–155. © 2016 SETAC
Veränderung der Boden‐ und Felsklassen in der VOB, Teil C (2015)
Authors: Borchert Kurt‐M. , Große Almuth 
Published: June 2016

AbstractMit Erscheinen des Ergänzungsbands 2015 zur VOB, Ausgabe 2012, wurden in allen ATV‐Normen die bisherigen Klassen durch Homogenbereiche für Boden und Fels ersetzt. Zur Beschreibung der Homogenbereiche werden in diesen Normen, die nach Abschnitt 2 – Stoffe und Bauteile, den Baugrund behandeln müssen, Eigenschaften und Kennwerte vorgegeben, die in der Leistungsbeschreibung anzugeben sind. In diesem Artikel werden die Änderungen durch die Einführung der Homogenbereiche im Vergleich zu den bisherigen Klassen dargestellt und Hinweise für die Baugrunduntersuchungen und zugehörigen Planungen gegeben.Improvement of soil and rock classes in all VOB‐codes, part C (2015). In 2015 the supplement to the VOB, issue 2012, was released. In all ATV standards the previous soil categories were substituted by homogenous zones for soil and rock. Chapter 2 of this standard, named Material and Construction Elements is dealing with the subsoil conditions. To describe the homogenous zones in these standards, properties and characteristic values are specified, which have to be provided as part of the general technical specifications. In this paper the changes induced by the introduction of the homogenous zones will be represented by means of comparison to the previous soil categories. In addition, advice for ground investigation und associated design will be paid attention to.
Neuroanatomic pathways associated with monoaminergic dysregulation after stroke
Authors: Hama Seiji , Murakami Taro , Yamashita Hidehisa , Onoda Keiichi , Yamawaki Shigeto , Kurisu Kaoru 
Published: June 2016

ObjectiveWe examined the complex relationship between lesion location, symptoms of depression (affective and apathetic), and monoamine dysfunction after stroke.MethodsMagnetic resonance imaging was performed on 48 post‐stroke patients that had been assessed for affective and apathetic symptoms using the Hospital Anxiety and Depression Scale and the Apathy Scale, respectively. Noradrenalin (NA), dopamine (DA), their metabolites, and a metabolite of serotonin (5‐HT) were measured using 24‐h urine samples, and 5‐HT and 3‐methoxy‐4‐hydroxyphenylglycol were measured using blood samples. We developed a statistical parametric map that displayed the associations between lesion location and both positive and negative alterations of monoamines and their metabolites.ResultsMultivariate analysis indicated that basal ganglia lesions and 5‐HT showed relationships with affective symptoms, whereas homovanillic acid was related to apathetic symptoms. Univariate analysis showed no such relationships. However, decreases in NA and DA and increases in NA and DA turnover were related to lesions in the brainstem, whereas increases in NA and DA as well as decreases in NA and DA turnover were related to cortical and/or striatum lesions. 5‐HT turnover data showed a pattern opposite to that seen for NA and DA turnover.ConclusionsMonoaminergic neuronal pathways are controlled by both receptor‐mediated feedback mechanisms and turnover; thus, depletion of monoamines is not the only cause of depression and apathy. Moreover, the monoamine neuronal network might be divided into two branches, catecholamine (NA and DA) and 5‐HT, both of which are anatomically and functionally interconnected and could respectively influence apathetic and affective symptoms of depression.