bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stacks off tracks: A role for the golgin AtCASP in plant endoplasmic reticulum – Golgi apparatus tethering
Authors: Osterrieder Anne , Botchway Stan W , Ward Andy , Ketelaar Tijs , de Ruijter Norbert , Hawes Chris 
Published: March 2017

AbstractThe plant Golgi apparatus modifies and sorts incoming proteins from the endoplasmic reticulum (ER), and synthesises cell wall matrix material. Plant cells possess numerous motile Golgi bodies, which are connected to the ER by yet to be identified tethering factors. Previous studies indicated a role of cis-Golgi plant golgins (long coiled-coil domains proteins anchored to Golgi membranes) in Golgi biogenesis. Here we show a tethering role for the golgin AtCASP at the ER-Golgi interface. Using live-cell imaging, Golgi body dynamics were compared in Arabidopsis thaliana leaf epidermal cells expressing fluorescently tagged AtCASP, a truncated AtCASP-ΔCC lacking the coiled-coil domains, and the Golgi marker STtmd. Golgi body speed and displacement were significantly reduced in AtCASP-ΔCC lines. Using a dual-colour optical trapping system and a TIRF-tweezer system, individual Golgi bodies were captured in planta. Golgi bodies in AtCASP-ΔCC lines were easier to trap, and the ER-Golgi connection was more easily disrupted. Occasionally, the ER tubule followed a trapped Golgi body with a gap, indicating the presence of other tethering factors. Our work confirms that the intimate ER-Golgi association can be disrupted or weakened by expression of truncated AtCASP-ΔCC, and suggests that this connection is most likely maintained by a golgin-mediated tethering complex.HighlightHere we show that the Golgi-associatedArabidopsis thalianaprotein AtCASP may form part of a golgin-mediated tethering complex involved in anchoring plant Golgi stacks to the endoplasmic reticulum (ER).
The temporal paradox of Hebbian learning and homeostatic plasticity
Authors: Zenke Friedemann , Gerstner Wulfram , Ganguli Surya 
Published: March 2017

AbstractHebbian plasticity, a synaptic mechanism which detects and amplifies co-activity between neurons, is considered a key ingredient underlying learning and memory in the brain. However, Hebbian plasticity alone is unstable, leading to runaway neuronal activity, and therefore requires stabilization by additional compensatory processes. Traditionally, a diversity of homeostatic plasticity phenomena found in neural circuits are thought to play this role. However, recent modelling work suggests that the slow evolution of homeostatic plasticity, as observed in experiments, is insufficient to prevent instabilities originating from Hebbian plasticity. To remedy this situation, we suggest that homeostatic plasticity is complemented by additional rapid compensatory processes, which rapidly stabilize neuronal activity on short timescales.
Genotype-phenotype association mining in bipolar disorder: market research meets complex genetics
Authors: Breuer René , Mattheisen Manuel , Frank Josef , Krumm Bertram , Treutlein Jens , Kassem Layla , Strohmaier Jana , Herms Stefan , Mühleisen Thomas W. , Degenhardt Franziska , Cichon Sven , Nöthen Markus M. , Karypis George ,   Bipolar Disorder Genetics (BiGS) Consortium, McMahon Francis J. , Rietschel Marcella , Schulze Thomas G. 
Published: March 2017

AbstractDisentangling the etiology of common, complex diseases is a major challenge in genetic research. For bipolar disorder (BD), several genome-wide association studies (GWAS) have been performed. Similar to other complex disorders, major breakthroughs in explaining the high heritability of BD through GWAS have remained elusive. To overcome this dilemma, genetic research into BD, has embraced a variety of strategies such as the formation of large consortia to increase sample size and sequencing approaches. Here we advocate a complementary approach making use of already existing GWAS data: applying a data mining procedure to identify yet undetected genotype-phenotype relationships. We adapted association rule mining, a data mining technique traditionally used in retail market research, to identify frequent and characteristic genotype patterns showing strong associations to phenotype clusters. We applied this strategy to three independent GWAS datasets from 2,835 phenotypically characterized patients with BD. In a discovery step, 20,882 candidate association rules were extracted. Two of these - one associated with eating disorder and the other with anxiety - remained significant in an independent dataset after robust correction for multiple testing, showing considerable effect sizes (odds ratio ~ 3.4 and 3.0, respectively). Our approach may help detect novel specific genotype-phenotype relationships in BD typically not explored by analyses like GWAS. While we adapted the data mining tool within the context of BD gene discovery, it may facilitate identifying highly specific genotype-phenotype relationships in subsets of genome-wide data sets of other complex phenotype with similar epidemiological properties and challenges to gene discovery efforts.
The effect of directors’ and officers’ insurance on audit fees: the case of an emerging economy
Authors: Li Kuei-Fu , Liao Yi-Ping 
Published: March 2017

Purpose
The purpose of this paper is to examine the role of D&O insurance in audit pricing in Taiwan, an emerging market in which auditors face negligible litigation risk and intense competition.

Design/methodology/approach
It examines the association between audit fees and D&O insurance coverage.

Findings
Results indicate that audit fees are higher for clients with higher D&O coverage after controlling for other determinants. Further analysis shows that auditors charge additional audit fees for clients whose insurer is foreign owned.

Originality/value
Overall, the study provides evidence that the induction of financial misstatement risks by D&O insurance is one of the contributing audit risk factors in an emerging economy context.
Abnormal returns using accounting information within a value portfolio
Authors: Banerjee Pradip , Deb Soumya G. 
Published: March 2017

Purpose
This paper investigates whether a simple accounting information-based fundamental analysis strategy could identify winners from losers within a portfolio of high book-to-market (value) stocks, over the last decade in the Indian equity market, where historically, information disclosure and transparency levels have been on the lower side.

Design/methodology/approach
Using a sample of ‘value’ firms, the authors formulate an ‘F-score’ for each firm as the sum of binary signals (favourable and unfavourable), with respect to nine key variables. The authors then form ten equal size F-score portfolios within the value band for each year, and track the performance of robust high F-score firms vis-à-vis that of weaker low F-score firms.

Findings
The study highlights that the historical success of a value strategy, in general, relies on the strong performance of a few firms while ‘tolerating the poor performance of many deteriorating companies’ within the broad value group and shows that firms with strong fundamentals within the value group outperform their less robust counterparts, based on absolute as well as risk adjusted measures.

Practical implications
The results of the study show that strong performers can indeed be distinguished from underperformers within the broad category of value stocks. This can have significant implications for investors at large in the Indian equity market.

Originality/value
The study suggests an approach to identify potential winners within a broad ‘value’ portfolio using an array of accounting information, even in a relatively less transparent Indian equity market.
Managing continuous innovation through performance measurement
Authors: Saunila Minna 
Published: March 2017

Purpose
The purpose of this paper is to define measures that small- and medium-sized enterprises (SMEs) can use for evaluating continuous innovation and to analyze types of SMEs, according to the innovation measures they use and their characteristics in terms of size and operational and financial performance.

Design/methodology/approach
The data were gathered with the help of a structured survey questionnaire from a cross-section of firms in both the manufacturing and service sectors in Finland. The data were analyzed in terms of factor and cluster analyses.

Findings
Three measures of continuous innovation and three types of SMEs were defined based on their continuous innovation measures. It was found that firms using all three types of innovation measures also register above-average financial and operational performance compared to those that do not.

Originality/value
This study attempts to improve the precision of performance measurement and the management of continuous innovation in firms by expanding and refining existing measurement guidelines and principles. In particular, this work approaches the subject of continuous innovation measurement from the standpoint of SMEs.
Role of human behaviour attributes in mobile crowd sensing: a systematic literature review
Authors: Agarwal Neetima , Chauhan Sumedha , Kar Arpan Kumar , Goyal Sandeep 
Published: March 2017

Purpose
Mobile crowd sensing (MCS) is a new paradigm enabled by Internet of Things (IoT) in which sensor-rich ubiquitous devices collect and share the data over a large geography. Human behaviour attributes (perception, comprehension and projection) play a key role in the decision-making process for sharing and processing the data. This study aims to understand how situation awareness plays an important role in MCS in an IoT ecosystem.

Design/methodology/approach
A systematic literature review was conducted by following a rigorous search protocol that identified a total of 470 peer-reviewed research papers. These papers were further filtered and finally 31 relevant papers were selected.

Findings
The major issues and concerns arising due to human participation in the MCS system were identified. Further, probable strategies were explored to deal with the challenges resulting due to certain human behaviour attributes.

Practical implications
This study provides the recommendations to address the major challenges related to the MCS system, which in turn may enhance the adoption of emerging smart technology-driven services.

Originality/value
The study is original and is based on the existing literature and its interpretation.
Developing broadband in frontier markets: opportunities and challenges in the Kurdistan Region of Iraq
Authors: Haddad Marolla , Rossotto Carlo Maria 
Published: March 2017

Purpose
This paper aims to explore how the Kurdistan Region of Iraq (KRI) can leverage broadband, as a frontier emerging market, to diversify the economy and promote growth, job creation and productivity. The objective is to analyze the challenges and opportunities of the broadband market and propose policies to boost its development and achieve medium to long-term economic benefits.

Design/methodology/approach
The paper uses qualitative and quantitative tools to study the legal and regulatory environment, market structure, competitive dynamics and available services and infrastructure in the KRI. The data and information analyzed were obtained through field research, primary data collection and consultation with government institutions, telecom operators and IT companies.

Findings
Obstacles to broadband development in the KRI are barriers to competition, the need for clearer and more transparent policies and regulations and a fragmented market. However, when the right conditions are in place, KRI has the potential to emerge as a regional hub for international broadband connectivity and significantly expand local broadband access.

Originality/value
This paper presents a first-of-its-kind baseline analysis of the telecom sector in the KRI. Very little information is available on the KRI market, which also has not been previously studied separately from the Iraqi market. Based on the fieldwork, the paper relies on region-specific data to analyze the particularity of the market and identify reforms within the prerogative of the regional government.
Do earnings really decline for older workers?
Authors: Charni Kadija , Bazen Stephen 
Published: March 2017

PurposeCross-section data suggest that the relationship between age and hourly earnings is an inverted U shape. Evidence from panel data does not necessarily confirm this finding suggesting that older workers may not experience a reduction in earnings at the end of their working life. The paper aims to discuss this issue.Design/methodology/approachIn this paper the authors use panel data on males for Great Britain in order to examine why the two types of data provide conflicting conclusions. Concentrating on the over 50s, several hypotheses are examined: overlapping cohorts, job tenure, job-changing, labour supply behaviour, and selectivity bias.FindingsCohort and individual fixed effects partly explain the divergent conclusions. However, for fully, year-on-year employed individuals, there is no evidence of earnings decline at the end of working life. The authors find no role for selectivity due to retirement, although shorter working hours or partial retirement along with job-changing late in life does provide an explanation for why hourly earnings decline for certain older workers.Originality/valueThe authors find no evidence that the process of ageing itself leads to lower earnings as suggested by the cross-section profile.
Logistics solutions for reducing food waste
Authors: Liljestrand Kristina 
Published: March 2017

Purpose
The purpose of this paper is to expand understandings of how logistics can reduce food waste in food supply chains (FSCs).

Design/methodology/approach
Using a research framework that associates causes of food waste with logistics solutions, a multiple-case study was conducted in three Swedish FSCs of meat, fruit and vegetables, and ambient products, respectively, and involving industrial producers, wholesalers, and retailers. Data were collected during 19 semistructured interviews and four site visits, and logistics solutions were analysed according to logistics activities, actors involved and their stages in the FSC, and coordination mechanisms.

Findings
A joint analysis of nine logistics solutions revealed that to efficiently reduce food waste in FSCs, solutions have been implemented at three stages of FSCs, as well as that those solutions differ in their integration of six logistics activities and four coordination mechanisms. The findings moreover indicate that the solutions are interlinked, thereby implying that coordination is necessary both within solutions as well as among them.

Research limitations/implications
The chief limitation is that the potential of the identified logistics solutions is not quantified.

Practical implications
The paper makes recommendations for reducing food waste in FSCs by developing new solutions and modifying existing ones.

Social implications
The paper suggests ways to reduce significant environmental impacts of food waste.

Originality/value
By building upon previous research explaining causes of food waste, this paper focusses on logistics solutions for reducing such waste.
Inconsistencies in the behavioural effects of consumer ethnocentrism
Authors: Balabanis George , Siamagka Nikoletta-Theofania 
Published: March 2017

Purpose
Despite the well-established impact of consumer ethnocentrism (CET) on purchase intentions, extant literature offers limited evidence on actual purchase behaviour. The purpose of this paper is to address the gap by investigating the factors underlying variations in CET behaviour using reported brand purchases. Product category, product cost and visibility, brand and country of origin (COO) of purchased products are investigated for their impact on the differences in the behavioural effects of CET.

Design/methodology/approach
This study uses survey data collected in the USA from a sample of 468 consumers. Self-reported brand purchases are used and involve ten product categories, 432 brands, and 22 countries of origin. Logistic regressions for repeated measures are used to test the hypotheses formulated.

Findings
The results confirm that product category is an important determinant of the behavioural effects of CET. CET also has a significant impact on purchases of the most expensive product categories rather than frequently purchased convenient items. Contrary to existing empirical evidence, cultural similarity does not mitigate the negative effects of CET and product visibility does not strengthen the behavioural effect of CET.

Practical implications
The study results should enhance managers’ understanding of the determinants of ethnocentric behaviour. The results caution managers about the value of self-reported measures and indicate that product features other than COO may be more effective in mitigating the negative effects of CET.

Originality/value
This study contributes to extant literature on CET and COO by investigating, for the first time, the problem of inconsistent predictions of purchase behaviour in the context of foreign vs domestic brands. For this purpose, the study adopted a novel methodological approach to investigate actual brand purchases.
The EU as superordinate brand origin: an entitativity perspective
Authors: Diamantopoulos Adamantios , Herz Marc , Koschate-Fischer Nicole 
Published: March 2017

Purpose
Drawing from the entitativity theory, the purpose of this paper is to focus on the European Union (EU) as a superordinate entity and investigate the extent to which a “Made-in-EU” designation leads to superior/inferior brand evaluations and through them to higher/lower purchase intentions than different country-specific designations.

Design/methodology/approach
Prior literature and qualitative interviews with consumers are used to generate several propositions regarding the role of the EU as a brand origin. These are subsequently tested in a series of four experimental studies using a common design but different country-specific origins as stimuli.

Findings
While a “Made-in-EU” designation is interpreted as a quality signal, linking a brand to the EU fails to generate positive affective associations. Furthermore, the exact impact of a “Made-in-EU” brand designation very much depends on the standard of comparison, that is, the specific country against which the EU is evaluated.

Research limitations/implications
Superordinate designations such as the EU can indeed represent distinct entities in consumers’ minds which strongly impact their perceptions and intended behavior.

Practical implications
Moving from a “home country” label to a “Made-in-EU” label is not advisable for owners of domestic brands. For foreign brands from EU countries with an unfavorable country image, adopting a “Made-in-EU” label is worth considering since it can strengthen quality perceptions. However, any quality advantage might be offset by weaker brand affect perceptions.

Originality/value
The concept of entitativity introduces a new conceptual lens in the context of origin research which – almost exclusively – has previously focused on the individual country as the unit of analysis.
Risk assessment in sentencing decisions: a remedy to mass incarceration?
Authors: Kopkin Megan R. , Brodsky Stanley L. , DeMatteo David 
Published: March 2017

Purpose
The legal system’s use of risk assessment has grown exponentially over the past several decades. Empirically validated risk measures are commonly implemented in parole, bail, civil commitment, and presentence proceedings. Despite their growing popularity, both policy-makers and legal scholars question their moral and legal acceptability, particularly in presentence proceedings. The purpose of this paper is to assess the current role of risk assessment in sentencing through an examination of the instrument currently under construction in the state of Pennsylvania.

Design/methodology/approach
Drawing on the current state of the literature, this paper evaluates the current use of risk assessment in criminal sentencing and discusses its consequences, both positive and negative.

Findings
Four areas for improvement in the use of risk assessment in sentencing were identified. Recommendations for change are proposed.

Practical implications
While the use of risk assessment within the legal system has significantly increased over the past several decades, the incorporation of risk assessment in presentence proceedings is a relatively new practice. This paper provides readers with insight on the appropriateness of using risk assessment in this context and provides suggestions for reducing ethical concerns. Recommendations for increasing the validity and clinical utility of these instruments are also discussed.

Originality/value
Although the literature on the use of risk assessment in legal proceedings is dense, relatively little is written about their use in criminal sentencing. This paper introduces readers to this concept by examining a risk measure proposed for use in the state of Pennsylvania’s presentence proceedings. The authors discuss concerns and propose recommendations for the future use of risk assessment in this setting.
Neopatrimonialism, good governance, corruption and accounting in Africa
Authors: Hopper Trevor 
Published: March 2017

PurposeThe purpose of this paper is to reflect on how best to design, implement and assess accounting reforms in Africa.Design/methodology/approachA cross-disciplinary literature review.FindingsWhilst neopatrimonialism inhibits optimal development, some forms do not block it. Such governance often permeates African politics and reforms directed at its elimination may fail due to a lack of political will. Thus accounting reforms should recognize their political feasibility and be directed at areas congruent with strengthening attributes of a developmental state.Research limitations/implicationsThere is a need to evaluate accounting reforms with respect to the level of a country’s development, relate them to its political governance, and evaluate them with respect to incremental rather than absolute achievement of their aims.Practical implicationsRather than relying on imported “best practice” accounting standards and systems, there is a need for greater indigenous involvement to create systems that meet local needs and circumstances to increase indigenous accounting capacity and will to reform.Social implicationsWhilst the push to good governance is a desirable ideal, reforms need to be pragmatic with respect to feasibility.Originality/valueThe paper relates recent work on development to accounting reform in Africa which has been neglected by accounting scholars and practitioners.