bluuebunny/crossref_metadata_2025_split huggingface dataset:
Follicular Lymphoma in Chile in the Adult Public Cancer Program: The Impact of Chemoimmunotherapy
Authors: Cabrera María Elena , Peña Camila , Vega Valeska , Rojas Hernán , Pizarro Alvaro , Rojas Christine , Calderon Susana , Oliva Jacqueline , Hales Cecilia , Rojas Bernardita , Intriago Marvila , Capurro Marisa , Gonzalez M. Luisa , Castillo Jorge J. 
Published: September 2024

ABSTRACTBackgroundFollicular lymphoma (FL) is the most common indolent non‐Hodgkin lymphoma (NHL) in the United States and Europe. However, data on FL from Latin America are scant.AimsThis study aims at better understand the clinical features, treatment patterns and outcomes of patients with FL in Chile. Of special interest was to evaluate POD24 as an adverse marker.Methods and ResultsWe collected retrospective data from 722 patients 15 years or older diagnosed with FL and treated in 17 cancer centers in Chile between 2000 and 2019. Time to first treatment (TTFT), progression‐free survival (PFS) and overall survival (OS) were estimated using the Kaplan–Meier method. Cox proportional‐hazard regression models were fitted to investigate prognostic factor. The median age at diagnosis was 62 with a female predominance (63%); 73% of patients had advance stage disease and 68% had bone marrow involvement; 63% had intermediate or high FLIPI scores. The 1‐year TTFT rate was 96%, and 30% of patients received chemoimmunotherapy. Adding rituximab to chemotherapy was associated with a higher complete response (69% vs. 60%; p < 0.001) and superior median OS (16 vs. 8 years; p < 0.001). Patients who experience POD24 had an inferior median OS (2.4 vs. 15 years).ConclusionOur study shows a female predominance in patients with FL in Chile and confirms superior response and survival outcomes with adding rituximab to chemotherapy. Our study also confirms a poor OS in patients who experience POD24.
Dexamethasone Inhibits the Growth of B‐Lymphoma Cells by Downregulating DOT1L
Authors: Wang Yuting , Zhang Nan , Shang Weilong , Peng Huagang , Hu Zhen , Yang Yi , Tan Li , Zhang Li , He Fengtian , Rao Xiancai 
Published: September 2024

ABSTRACTBackgroundDexamethasone (Dex), a synthetic glucocorticoid that acts by binding to the glucocorticoid receptor (GR), has been widely applied to treat leukemia and lymphoma; however, the precise mechanism underlying Dex action is still not well elucidated. DOT1L, a histone H3‐lysine79 (H3K79) methyltransferase, has been linked to multiple cancer types, particularly mixed lineage leukemia (MLL) gene rearranged leukemia, but its contribution to lymphoma is yet to be delineated. Analysis from the TCGA database displayed that DOT1L was highly expressed in lymphoma and leukemia.ResultsWe initially demonstrated that DOT1L served as a new target gene controlled by GR, and the downregulation of DOT1L was critical for the killing of B‐lymphoma cells by Dex. Further study revealed that Dex had no impact on the transcriptional activity of the DOT1L promoter, rather it reduced the mRNA level of DOT1L at the posttranscriptional level. In addition, knockdown of DOT1L remarkably inhibited the B‐lymphoma cell growth.ConclusionsOverall, our findings indicated that DOT1L may serve as a potential drug target and a promising biomarker of Dex sensitivity when it comes to treating B lymphoma.
Demographics, Histopathology, and Treatment Outcomes of Squamous Cell Carcinoma of the Prostate
Authors: Gordon Julian A. , Larkins Michael C. , Siripurapu Vaishnavi , Bhatt Arjun , Pasli Melisa , Armel Kristen , Velez‐Martinez Carol , Mitsakos Anastasios , Burke Aidan , Peach M. Sean 
Published: September 2024

ABSTRACTBackgroundSquamous cell carcinoma of the prostate (SCCP) is a neoplasm that comprises fewer than 1% of all primary prostate cancer diagnoses. Given its rarity, there is a paucity of data regarding the treatment of this disease. The limited literature points to the potential of local therapy in conjunction with chemotherapy to improve patient mortality.MethodsUsing the National Cancer Initiative's Surveillance, Epidemiology, and End Results (SEER) database, a retrospective review of patients diagnosed with primary SCCP between 2000 and 2018 was performed. Patient demographics, tumor characteristics, and patient outcomes based on treatment modality were analyzed. Univariate and survival analyses were conducted with p < 0.05 indicating statistical significance.ResultsA total of 66 patients were identified. Five‐year overall survival (5y OS) was 24%; mean and median survival were 2.2 years (1.8, 2.7) and 1.2 years (0.3, 2.1), respectively. Patients with Grade I or Grade II disease had an increased 5y OS of 55% (27%, 83%). In comparison, 5y OS was 13% (−2%, 29%) for patients with Grade III and Grade IV disease (p = 0.017). Analysis of 5y OS based on disease histology revealed patients with papillary SCC had a 5y OS of 50% [9.2%, 91%], compared to 21% [9%, 34%] for patients with SCC, not otherwise specified and 0% for those with lymphoepithelial carcinoma (p = 0.048). Analysis of 5y OS stratified by treatment modality revealed no statistically significant change with any treatment (surgery, radiotherapy, and chemotherapy). No difference in 5y OS was seen between those treated with radical prostatectomy versus external beam radiation therapy.ConclusionsThe literature on SCCP remains sparse; the rarity of this disease limits analysis. While the investigation undertaken in this paper does not find any change in 5y OS regardless of treatment modality, the variation in 5y OS based on histologic classification of SCCP points to a potential route for the future treatment of this disease.
Sparse representation of finger knuckle print images for personal identification
Authors: Charfi Nesrine , Tounsi Maroua , Solaiman Basel 
Published: September 2024

SummaryFraud keeps increasing in our society and security applications become crucial and needed in our daily life. Biometric technology attempts to stop fraud and falsification in different opportunities such as bank services, access to controlled areas or crossing frontiers, by recognizing the identity of a person using his physiological (fingerprint, iris, face) or behavioral modalities (gait, signature). In this article, we focus on an emerging biometric modality called the finger knuckle print (FKP). In fact, this modality has several advantages such as the easy distinction between different persons, stability over time and user acceptance. So, an FKP identification approach is proposed using scale invariant feature transform descriptors based sparse representation method. The classification step, between training and testing FKP samples, is made using the support vector machines method. Experiments applied on two public FKP databases: The Hong Kong Polytechnic University (PolyU) Contactless Finger Knuckle Images Database and the Indian Institute of Technology Delhi (IITD) Finger Knuckle Database, containing respectively 2500 and 790 images, demonstrate high correct identification rates by reaching 98.58% and 99.15% for these two databases.
Synthesis of N‐Sulfopropylated Hyperbranched Polyethyleneimine with Enhanced Biocompatibility and Antimicrobial Activity
Authors: Panagiotaki Katerina N. , Lyra Kyriaki‐Marina , Papavasiliou Aggeliki , Stamatakis Kostas , Sideratou Zili 
Published: September 2024

AbstractHyperbranched polyethyleneimine having 25,000 Da molecular weight was functionalized by a simple sulfopropylation reaction, affording a novel N‐sulfopropylated PEI derivative (PEI‐SO3−). The successful introduction of N‐sulfopropyl and sulfobetaine groups to the amino groups of PEI was spectroscopically confirmed. Furthermore, the antibacterial and anti‐cyanobacterial activity of PEI‐SO3− in comparison to the parent PEI were investigated on two type heterotrophic bacteria, i. e., Gram (−) Escherichia coli and Gram (+) Staphylococcus Aureus bacteria, and one type of autotrophic cyanobacterium, i. e. Synechococcus sp. PCC 7942. Both PEI‐SO3− and PEI showed an enhanced, concentration‐dependent antibacterial and anti‐cyanobacterial activity against the tested bacteria strains, with PEI‐SO3− exhibiting higher activity than the parent PEI, signifying that the introduction of the sulfopropyl and sulfobetaine groups to the PEI amino groups enhanced the antibacterial and the anti‐cyanobacterial properties of PEI. In the case of cyanobacteria, PEI‐SO3− was found to affect the integrity of the photosynthetic system by the inhibition of Photosystem‐II electron transport activity. Cytocompatibility and hemocompatibility studies revealed that PEI‐SO3− exhibits high biocompatibility, suggesting that PEI‐SO3− could be considered as an attractive antibacterial and anti‐cyanobacterial candidate for various applications in the disinfection industry and also against the harmful cyanobacterial blooms.
Posttraumatic Stress Disorder Symptom Clusters, Exposure to Potentially Morally Injurious Events, and Aggression Among Army Veterans
Authors: Potik David , Einat Tomer , Idisis Yael 
Published: September 2024

ABSTRACTObjectiveVery few studies have examined the association between posttraumatic stress disorder (PTSD) symptom clusters and aggression since the change in PTSD diagnosis criteria a decade ago. Furthermore, these studies have used measures based on PTSD criteria of the DSM‐IV. The current study therefore examines the association between PTSD symptom clusters, exposure to potentially morally injurious events (PMIEs), and various types of aggression following the change in PTSD criteria and in accordance with the criteria of the DSM‐5‐TR.MethodA sample of 167 Israeli combat veterans completed validated self‐report questionnaires tapping PTSD symptoms, exposure to PMIEs, and aggression levels.ResultsOur analysis revealed a significant positive relationship between the number of court‐martials, betrayal‐based PMIEs, all PTSD symptom clusters, and aggression. We also found that the arousal cluster, as well as the number of court‐martials and age, predicted aggression, whereas the re‐experiencing cluster predicted lower aggression levels.ConclusionBesides an updated understanding of the association between all PTSD symptom clusters and various forms of aggression, these findings emphasize the importance of targeting arousal symptoms and especially anger in treatment of veterans with PTSD symptoms and those who report experiences of betrayal. The findings also suggest clinicians to consider arousal symptoms, age, and history of court‐martials when conducting either clinical or actuarial risk assessments of veterans.
Toward Wearables for Bruxism Detection: Voluntary Oral Behaviors Sound Recorded Across the Head Depend on Transducer Placement
Authors: Nahhas Mohammad Khair , Türp Jens Christoph , Cattin Philippe , Gerig Nicolas , Wilhelm Elisabeth , Rauter Georg 
Published: September 2024

ABSTRACTObjectivesBruxism is a parafunctional orofacial behavior. For diagnosis, wearable devices that use sounds as biomarkers can be applied to provide the necessary information. Human beings emit various verbal and nonverbal sounds, making it challenging to identify bruxism‐induced sounds. We wanted to investigate whether the acoustic emissions of different oral behaviors have distinctive characteristics and if the placement of the transducer has an impact on recording the sound signals.Material and MethodsSounds from five oral behaviors were investigated: jaw clenching, teeth grinding, reading, eating, and drinking. Eight transducers were used; six were attached to the temporal, frontal, and zygomatic bones with the aid of medical tape, and two were integrated into two commercial earphones. The data from 15 participants were analyzed using time‐domain energy, spectral flux, and zero crossing rate (ZCR).ResultsIn summary, all oral behaviors showed distinct characteristic features except jaw clenching, though there was a peak in the recording, possibly due to tooth tapping, before its expected onset. For teeth grinding, the transducer placement did not have a significant impact (p > 0.05) based on energy, spectral flux, and ZCR. For jaw clenching, the transducer placement had an impact with regard to spectral flux (p < 0.01). For reading and eating, the transducer placement had a significant impact with regard to energy (p < 0.05 for reading, p < 0.01 for eating), spectral flux (p < 0.001 for reading, p < 0.01 for eating), and ZCR (p < 0.001 for both reading and eating). For drinking, the transducer placement only had a significant impact with regard to ZCR (p < 0.01).ConclusionsWe were able to record the sounds of various oral behaviors from different locations on the head. However, the ears were an advantageous location to place the transducer, since they could compensate for various head movements and ear devices are socially tolerable.
Molecular analysis of St. Augustinegrass cultivar mixtures composition over time and latitude
Authors: van der Laat Rocio , Leon Ramon G. , Dale Adam G. , Gouveia Beatriz , Carbajal Esdras M. , Schiavon Marco , Unruh J. Bryan , Iannone Basil V. , Milla‐Lewis Susana R. 
Published: September 2024

AbstractSt. Augustinegrass [Stenotaphrum secundatum (Walt.) Kuntze] is commonly planted in residential and commercial landscapes as a cultivar monoculture predisposing this lawn to pest invasion and high‐maintenance inputs. Researchers have suggested that increasing genetic diversity by growing cultivars in mixtures may increase turfgrass stress resilience. However, the stability and uniformity of those mixtures has not been studied. The present study was carried out to evaluate the stability of St. Augustinegrass cultivars mixtures over time and across three latitudes. The study was conducted in Citra and Fort Lauderdale, FL, and Jackson Springs, NC. Simple‐sequence repeats markers were used to genotype leaf samples of St. Augustinegrass cultivars planted in two‐ and four‐cultivar mixtures. Leaf samples were collected 1 and 3 years after establishment. In all locations, cultivar richness and evenness declined over time. Similarly, the relative abundance of the least persistent cultivars decreased approximately 50%–100% depending on cultivar and location. Differences in growth patterns among cultivars resulted in cultivar displacement and the predominance of a single cultivar. Cultivars that covered the ground faster or formed dense canopies early after establishment were dominant at the end of the study. Locally developed cultivars tended to be more dominant in their original latitude. The use of cultivar mixtures may help the identification of vigorous, competitive, and stress tolerant cultivars in turfgrass breeding programs. However, their commercial use remains challenging as if the patterns observed here for 3 years are representative of a continuous trend, and they do not persist over time.
Green human resource practices and corporate sustainable performance—The role of corporate green culture and dynamic capabilities
Authors: Hu Wei , Xu Yan , Yang Junyi 
Published: September 2024

AbstractSustainable development has always been a hot topic in academia and business circles. The green human resource practices play an important role in the sustainable development of enterprises. However, research on how green human resource practices can improve corporate sustainable performance is relatively scarce. In order to explore the internal mechanism and boundary conditions of the impact of green human resource practice on the sustainable performance of enterprises, the research is based on the dynamic capability theory, through the survey data of 460 enterprise managers. The hierarchical regression and bootstrapping methods are used to analyze the relationship mechanism and boundary conditions between green human resource practice and enterprise sustainable performance through dynamic capabilities. The research results show that green human resources have a positive impact on the sustainable performance and dynamic capabilities of enterprises; dynamic capabilities mediates the relationship between green human resource practices and corporate sustainable performance; corporate green culture not only enhances the relationship between green human resource practices and dynamic capabilities, but also enhances the mediating role of dynamic capabilities in green human resource practices and corporate sustainable performance. The research conclusions lay a theoretical foundation for the implementation of green human resource practices and provided a decision‐making reference for the sustainable development of enterprises.
Task‐Specific Deep Eutectic Solvent for Efficient Dissolution and Further Accelerating Alkaline Hydrolysis of Polyesters Into Their Monomers
Authors: Qin Rui , Wang Zeyu , Cao Yuanyuan , Tian Yurun , Zhou Fengyi , Li Zhiyong , Mu Tiancheng 
Published: September 2024

AbstractPolyester plastics have brought great convenience to modern society. However, the continuous accumulation of their production increasingly threatens human health. Polyethylene terephthalate (PET) is one of the largest type of polyester plastics and its recycling is a major challenge. In this work, deep eutectic solvent (DES) composed of thenyl alcohol and choline chloride (ChCl) was designed for efficient dissolution of PET at 165 °C for 20 min, and further accelerating complete alkaline hydrolysis of PET into its monomer terephthalic acid (TPA) and ethylene glycol (EG) with a high TPA monomer yield (98.2 %) in 25 min at 100 °C. Moreover, the designed DES is also efficient for dissolution and alkaline hydrolysis of other polyester plastics, including poly(trimethylene terephthalate) (PTT) and poly(ethylene furanoate) (PEF) into their monomers. This work provides a feasible and sustainable solution for the recycling of polyester wastes.
Clinical and translational mode of single‐cell measurements: An artificial intelligent single‐cell
Authors: Wang Xiangdong , Powell Charles A. , Ma Qin , Fan Jia 
Published: September 2024

AbstractWith rapid development and mature of single‐cell measurements, single‐cell biology and pathology become an emerging discipline to understand the disease. However, it is important to address concerns raised by clinicians as to how to apply single‐cell measurements for clinical practice, translate the signals of single‐cell systems biology into determination of clinical phenotype, and predict patient response to therapies. The present Perspective proposes a new system coined as the clinical artificial intelligent single‐cell (caiSC) with the dynamic generator of clinical single‐cell informatics, artificial intelligent analyzers, molecular multimodal reference boxes, clinical inputs and outs, and AI‐based computerization. This system provides reliable and rapid information for impacting clinical diagnoses, monitoring, and prediction of the disease at the single‐cell level. The caiSC represents an important step and milestone to translate the single‐cell measurement into clinical application, assist clinicians’ decision‐making, and improve the quality of medical services. There is increasing evidence to support the possibility of the caiSC proposal, since the corresponding biotechnologies associated with caiSCs are rapidly developed. Therefore, we call the special attention and efforts from various scientists and clinicians on the caiSCs and believe that the appearance of the caiSCs can shed light on the future of clinical molecular medicine.
Tree diversity across the Minneapolis‐St. Paul Metropolitan Area in relation to climate and social vulnerability
Authors: Keller Adrienne B. , Brandt Leslie A. , Cavender‐Bares Jeannine , Knight Joseph F. , Hobbie Sarah E. 
Published: September 2024

AbstractUrban tree canopy cover is often unequally distributed across cities such that more socially vulnerable neighborhoods often have lower tree canopy cover than less socially vulnerable neighborhoods. However, how the diversity and composition of the urban canopy affect the nature of social‐ecological benefits (and burdens), including the urban forest's vulnerability to climate change, remains underexamined. Here, we synthesize tree inventories developed by multiple organizations and present a species‐specific, geolocated database of more than 600,000 urban trees across the 7‐county Minneapolis‐St. Paul (MSP) metropolitan area in the Upper Midwest of the United States. We find that tree diversity across the MSP is variable yet dominated by a few species (e.g., Fraxinus pennsylvanica, Acer platanoides, and Gleditsia triacanthos), contributing to the vulnerability of the MSP urban forest to future climate change and disturbances. In contrast to tree canopy cover, tree diversity was not well predicted by socioeconomic or demographic factors. However, our analysis identified areas where both climate and social vulnerability are high. Our results add to a growing body of literature emphasizing the importance of considering how complex and interacting social and ecological factors drive urban forest diversity and composition when pursuing management objectives.
Retirements of professional tennis players in ATP and WTA tour events
Authors: Oliver Lia , Baiget Ernest , Cortés Jordi , Martínez Joan , Crespo Miguel , Casals Martí 
Published: September 2024

AbstractProfessional tennis competition at the highest levels requires high physical, technical, tactical, and mental demands. Player retirement is a scenario that often occurs at the highest echelons of the game. The objective of this study was to descriptively determine which factors influence retirement of matches in tennis. Matches from the Women's Tennis Association (WTA) and Association of Tennis Professionals (ATP) tours played over 44 and 46 years were included in the study, respectively. The results showed an increasing trend in the incidence of retirements in both ATP and WTA events, especially in recent years. Factors associated with the match characteristics, such as the type of surface, the type of tournament, and the round of the draw, were shown to influence retirement. Variables associated with player characteristics, such as the age difference between players, did not show to influence retirement, whereas the ranking difference did. When comparing ATP and WTA matches, similar results were observed in which surfaces and tournaments had the highest or lowest incidence of retirements. On the other hand, as per the rounds, the results are not conclusive. The findings highlight the growing trend of match retirements in professional tennis and emphasize the relevant influence of match characteristics such as surface type, tournament type, and round of the draw. These insights can guide coaches, players, and tournament organizers in developing strategies to mitigate retirements and inform future research on enhancing player longevity and performance in tennis.
Analyzing thermal‐moisture comfort and thermal protective performance of phase change materials dripped protective clothing
Authors: Gu Zihan , Su Yun , Fan Yuwei , Tian Miao , Li Jun 
Published: September 2024

AbstractThe objective of the study was to alleviate the thermal‐moisture comfort (TMC) of phase change material (PCM) thermal protective clothing, while simultaneously enhancing thermal protective performance (TPP) by a drip molding process. Nine types of PCM dripped fabrics were prepared by the drip molding process and served as comfort layers of thermal protective clothing. The TMC and TPP of the fabric systems were measured. A new method was proposed to balance the TMC and TPP of thermal protective clothing. The results demonstrated that the drip molding process marginally weakened the TMC while substantially enhancing the TPP of fabric systems. But the TMCs of the PCM dripped fabrics were far larger than the PCM coated fabric. Specifically, an increase in droplet diameter led to a decline in TMC and an improvement in TPP, whereas an increase in droplet interval resulted in an enhancement in TMC and a decrease in TPP. The findings obtained in this study can be used to engineer fabric systems that provide better protection for heat stress and skin burns.