bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-agent system simulation and centralized optimal model for groundwater management considering evaluating the economic and environmental effects of varied policy instruments implemented
Authors: Kamali Asghar , Niksokhan Mohammad Hossein , Ardestani Mojtaba 
Published: September 2024

ABSTRACT

Modeling interconnectedness of people (social) and nature (ecological) can offer valuable understanding about the dynamics in the midst of social and environmental processes. Within this paper, a novel framework based on Multi-Agent System Simulation (MASS) is introduced that use python-based codes coupling NETLOGO agent-based model platform with a calibrated MODFLOW groundwater model that uses SWAT watershed model by considering the uncertainty associated with farmers' productivity. Then the various policy instruments implemented in the MASS (free-access and consistent tax and quota on groundwater utilization) are compared with the Centralized Optimal Model (COM). In the COM streamflow constraints are imposed by a central planner with impeccable foresight that use MATLAB-based codes coupling the MATLAB with a calibrated groundwater model of MODFLOW that uses SWAT watershed model. This comparison that is one of the most important goals of this paper is based on their environmental and economic impacts. The environmental and economic impacts are measured using two main indicators: the violation of streamflow (VSF) and the average annual benefit (AAB). The results indicate that simulation with agents that are more realist, heterogeneous, shortsighted, and self-interested agents (MASS) perform poorly under consistently applied policies in comparison with COM.
INIQUIDADES INTERSECCIONAIS NO ATENDIMENTO OBSTÉTRICO ÀS MULHERES NEGRAS DE COMUNIDADE QUILOMBOLA
Authors: Damasceno Alycia Lara Souza , Arruda Amália Gonçalves , Barbosa Elane da Silva , Fernandes Helder Matheus Alves 
Published: September 2024

Introdução: A conjuntura socioeconômica e cultural da mulher negra a coloca em tripla vulnerabilidade, que se explica pelo fato de que ela é vítima do racismo, do preconceito de classe e da discriminação de gênero, e essa interação de diferentes tipos de opressão é explicada pela teoria da interseccionalidade. Esse negligenciamento precariza-se ainda mais quando se reporta para a atenção à saúde. Objetivo: Compreender como o contexto social da interseccionalidade de raça, classe e gênero refletem no atendimento obstétrico em Saúde Pública de mulheres negras residentes em comunidade quilombola. Metodologia: Trata-se de pesquisa qualitativa de caráter descritivo-exploratório, realizada com duas mulheres negras residentes em comunidade quilombola, localizada em município no interior do estado do Ceará. Como instrumento para coleta de dados, utilizou-se a entrevista semiestruturada, sendo os dados submetidos à análise do discurso. Resultados: Os sujeitos desta investigação conseguem, a partir de situações do quotidiano vivenciadas nos serviços de saúde públicos, identificar exemplos de racismo e/ou preconceito relacionados ao fato de serem mulheres negras e pobres. Assim, a vulnerabilidade interseccional (raça – gênero – classe social) implica em desigualdades no acesso aos serviços de saúde, o que se materializa em violência obstétrica, negligência em relação ao direito da mulher negra sobre o próprio corpo, além de negação da sua subjetividade, o que viola os pressupostos do Sistema Único de Saúde (SUS), particularmente os princípios da universalidade, equidade e integralidade da assistência. Conclusões: Constata-se, portanto, que as iniquidades quanto ao atendimento obstétrico, que afetam majoritariamente as mulheres negras e pobres, apresentam-se como problemática de gestão, denotando o déficit na efetivação de políticas públicas de saúde, ou a sua ausência. Há também a necessidade de que os profissionais de saúde, a partir de educação continuada, tenham um olhar mais holístico, a fim de produzir um atendimento equânime e integral.
Palavras-Chave: Quilombolas; Racismo; Obstetrícia; Classe social; Saúde pública.
Establishment of LC-MS/MS Methodology for the Determination of Rapamycin Concentration in Rat Whole Blood
Authors: Yang Yuanxia , Yang Miaoting , Wang Lijuan , He Liufang , Shi Tao 
Published: September 2024

Background:
The establishment and validation of methods for testing biological
samples are crucial steps in pharmacokinetic studies. Currently, several methodological reports
have been published on the detection of rapamycin plasma concentrations.

Objective:
The objective of this study was to explore an effective method for detecting rapamycin
in rat whole blood biological samples.

Method:
In this study, we designed a rapid, sensitive, and specific liquid chromatograph-mass
spectrometer/mass spectrometer (LC-MS/MS) methodology for detecting rapamycin in rat
whole blood biological samples. We comprehensively validated the specificity, linear range,
lower limit of quantification (LLOQ), precision, accuracy, recovery, and stability of this method.

Results:
The findings of this study confirmed the successful implementation of LC-MS/MS for
the detection of rapamycin, demonstrating its sensitivity, specificity, and reliability in quantitative
analysis. This method ensures the accuracy and reliability of subsequent study data through
our validated LC-MS/MS approach.

Conclusion:
The results demonstrated the successful implementation of an LC-MS/MS method
for sensitive, specific, and reliable quantitative analysis of rapamycin in rat whole blood samples.
This method ensures the accuracy and reliability of subsequent study data.

Significance:
The importance of this study lies in the successful establishment of a rapid, sensitive,
and specific LC-MS/MS method for detecting rapamycin concentration in rat whole blood,
ensuring the accuracy and reliability of subsequent research data. This provides a crucial tool
and foundation for further understanding the metabolism and pharmacological effects of rapamycin
in vivo, aiding in the advancement of drug research and clinical applications in related
fields.
Management’s Communication Style When Disclosing Material Weaknesses in Internal Control
Authors: Brazel Joseph F. , Starliper Matthew , Yu Yao 
Published: September 2024

SYNOPSIS
Section 404 of the Sarbanes-Oxley Act requires management of publicly traded companies to assess and disclose the effectiveness of their internal controls over financial reporting (ICFR). In our analysis of 200 actual ICFR reports disclosing material weaknesses in internal control, we observe that the most common communication style in our sample is, among other characteristics, a more defensive version of the “reasonable assurance” argument combined with the use of first-person pronouns. In an experiment where we vary management’s communication style with respect to material weakness disclosures, we find that nonprofessional investors are more willing to invest in a company when management uses a version of the “reasonable assurance” argument with fewer characteristics of defensive communication and does not use first-person pronouns. Our findings show a sharp contrast between the communication styles management chooses to use in actual ICFR reports and what we observe experimentally as the most effective communication style.
Data Availability: Data are available from the authors upon request.
JEL Classifications: M40; M41.
Maternal Glycemia During Pregnancy and Child Lung Function: A Prospective Cohort Study
Authors: Yang Meng , Cao Zhongqiang , Li Wenqing , Zhou Jieqiong , Liu Jiuying , Zhong Yuanyuan , Zhou Yan , Sun Lingli , Li Ruizhen , Cai Xiaonan , Xiao Han , Zhou Aifen 
Published: September 2024

OBJECTIVE
Gestational diabetes mellitus (GDM) is known to be associated with certain respiratory impairments in offspring. However, the specific association between maternal GDM and childhood lung function remains unclear. We examined the association of maternal glycemia, as measured by oral glucose tolerance test (OGTT) values, with childhood lung function outcomes in a birth cohort.

RESEARCH DESIGN AND METHODS
A follow-up study was conducted with 889 children aged 6 years whose mothers underwent a 75-g OGTT between 24 and 28 weeks of gestation. After adjusting for prenatal and postnatal factors, multivariable regression models were used to evaluate the relationship between maternal glycemia and offspring lung function.

RESULTS
In total, 10.7% of the offspring were exposed to maternal GDM. Maternal GDM significantly reduced the z score of forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), and forced expiratory flow at 25–75% of FVC in children, with more pronounced effects in female offspring. Maternal 1- and 2-h post-OGTT glucose z scores and the sum of those z scores, but not those for fasting glucose, were inversely associated with several measures of children's lung function. Additionally, maternal GDM increased the risk of impaired lung function in children (odds ratio 2.64; 95% CI, 1.10–5.85), defined as an FVC &lt;85% of the predicted value. There were no significant associations with FEV1/FVC.

CONCLUSIONS
Maternal hyperglycemia was negatively associated with lung function in children, particularly among girls. Further studies are warranted to elucidate the underlying mechanisms of this association and to explore potential interventions to mitigate its effects.
Three-dimensional geological modelling of the eastern and western parts of the Hovsan field according to geological and geophysical data
Authors: Ahmedov T.R. , Kerimova K.A. , Khalilova L.N. 
Published: September 2024

The article considers the issue of volumetric modelling of productive formations of the Hovsan oil field using the PETREL software package.
The productive horizons QaS-2 and QaS-3 of the Qala Suite of the Productive Series in the eastern and western parts of the Hovsan field were taken as the object of the study. Geological and geophysical data for the research area were used to construct the model.
The Hovsan field is related to deposits of the Qala Suite in the western and eastern sections, separated by an industrially important oil-water zone. The deposits of the Qala Suite are divided into three horizons: (from top to bottom) QaS1 ― 57 m, QaS2 ― 70 m, and QaS3 ― 168 m. The total thickness of the Qala Suite is 250 m in the western part and 280 m in the eastern part.
The article explains in detail the methodology for building 3D models of the eastern and western parts of the Hovsan field using both geological and well data for the research area. It also includes a petrophysical model of the eastern and western parts of the Hovsan field and a lithological cube for volumetric lithologymodelling.
The paper shows that sands and sandstones (thickness 5―15 m), which are oil and gas reservoirs, are separated mainly in the upper and middle horizons, as well as in the top part of the lower layer of the lower horizon (thickness 30 m), which alternate with clay layers 2―3 m thick. The reservoir properties of the layers vary along the section and over the area.
Although the Hovsan field has been in production for more than 70 years, 3D geological and geophysical modelling was carried out for the first time for the eastern and western parts of the Qala Suite, which is considered promising in terms of productivity.For the first time, the research area was studied in detail from the point of view of lithology, petrophysics, and oil and gas content in the inter-well space using modelling based on 3D seismic data.On the other hand, 3D models are the basis for solving issues such as hydrocarbon resource estimation,justifying the drilling of new wells, monitoring resource development, and assessing the impact of waterflooding and production well operations.Using three-dimensional models made it possible to realise both long-term and operational forecasting when monitoring the exploitation of hydrocarbon fields.
Since the presence of new objects in the Qala Suite, considered promising in terms of productivity, is not in dispute, the study confirmstheir detection and monitoring with the application of three-dimensional models.
Así amamos: experiencias erótico-amorosas de hombres con discapacidad visual
Authors: Cervantes Flores Jesús Gerardo 
Published: September 2024

Así amamos: experiencias erótico-amorosas de hombres con discapacidad visual, es un proyecto de investigación-creación desde la comunicación alternativa que inició con una investigación de corte fenomenológico donde se realizaron entrevistas en profundidad a hombres con ceguera y culminó con una serie podcast de ficción.

Los principales hallazgos de la investigación concluyen que los hombres con ceguera han vivido de manera diferenciada sus experiencias erótico-amorosas en comparación con las personas normovisuales, quienes tienen poca sensibilización tienen hacia la discapacidad y a quienes les cuesta la idea de relacionarse amorosamente con una persona con ceguera. Los resultados se narran en la serie podcast que consta de cinco capítulos donde se abordan diversos temas de las experiencias erótico-amorosas de la población de estudio: autoerotismo, cortejo, primera vez, relaciones amorosas y ruptura.

Se concluye que la investigación-creación desde la comunicación alternativa es una forma de activar la expresión del otro ante la normalidad hegemónica.
Identifikasi Senyawa Flavonoid Ekstrak Daun Heredong Bulu (Clidemia hirta (L) D. Don) dengan Menggunakan Spektrofotometri Uv-Vis dan FTIR
Authors: Suprapto Prayitno  , Doloking Haeria , Ludgensia Indradewi Kurniati  
Published: September 2024

Abstrak
Pendahuluan: Daun heredong bulu secara empiric dipercaya mampu menyembuhkan bisul, dapat mengobati luka, mengobati infeksi karena memiliki kandungan kimia flavonoid, tanin, saponin, serta steroid. Senyawa flavonoid dan tanin berkhasiat sebagai antibakteri. Tujuan: Penelitian ini bertujuan untuk mengetahui dan mengidentifikasi golongan dan karakteristik senyawa flavonoid Ekstrak Daun Heredong Bulu (Clidemia hirta (L) D. Don). Metode: Penelitian ini dilakukan dengan metode maserasi menggunakan pelarut etanol 96%. Ekstak etanol difraksinasi menggunakan pelarut H2O dan etil asetat. Uji skrining fitokimia Ekstrak Daun Heredong Bulu (Clidemia hirta (L) D. Don) menunjukan positif mengandung flavonoid, dengan penambahan pereaksi NaOH, H2SO4 dan HCl pekat+serbuk Mg yang ditandai dengan warna merah dan kuning. Identitifikasi dengan Kromatografi Lapis Tipis (KLT) dengan eluen N-Heksan:Etil Asetat (6:4), (7:3), (8:2), (9:1). Penampakan noda yang baik yang dielusi dengan eluen N-Heksan:Etil Asetat (7:3), selanjutnya dilakukan pemisahan dengan Kromatografi Lapis Tipis Preparatif (KLTP) menggunakan eluen N-Heksan:Etil Asetat (7:3), diperoleh 6 fraksi. Hasil: Penelitian ini diperoleh uji identifikasi dengan menggunakan KLT dua dimensi dengan eluen N-Heksan:Etil Asetat (7:3) menghasilkan isolat pada fraksi 1, 2, 3, 4, 5, dan 6 adanya serapan panjang gelombang yang menujukan bahwa adanya senyawa flavonoid dengan gelombang yang berbeda pada tiap fraksi. dan pada spektro FTIR adanya gugus fungsi O-H. C-H, C=O, C-O dan C=C yang terkandung pada fraksi 1, 2, 3, 4, 5, dan 6. Kesimpulan: ekstrak daun heredong memilik senyawa flavonoid yaitu golongan flavom, flavonol, auron, antosianidin dan flovanon.

Kata Kunci: Ekstrak Daun Heredong, Flavon, Flavonol, Auron, Antosianidin, Flovanon, Spektro UV-Vis, FTIR
Comparative Evaluation of Two Different Single-Session Radiotherapy Regimens along with Zoledronic Acid in Painful Bone Metastases
Authors: Sanwaria Meenakshi , Kamra Puneet , Dhankhar Rakesh , Paul Diptajit , Gupta Kartik , Chauhan Ashok 
Published: September 2024

Abstract

Background
Bone metastases frequently occur in various types of cancer. External beam radiotherapy (EBRT) effectively alleviates the pain associated with these metastases. Various experimental studies have been conducted to see the effectiveness of single-session radiation along with bisphosphonates to control the pain of bone metastasis. In the present study, we compared two schedules of palliative EBRT in painful bony metastasis.

Patients and methods
We conducted a prospective study involving patients with bone metastases from any primary cancer. Patients were randomly assigned to receive palliative EBRT at either 8 Gy single session (group I) or 6 Gy single session (group II), along with zoledronic acid administered to the involved site in both groups. The primary objective was to evaluate overall pain response using the Glasgow pain scale and improvement in performance status measured by the Eastern Cooperative Oncology Group (ECOG) performance status score. Secondary objectives included assessing complete pain relief and the duration of overall pain response.

Results
A total of 60 patients were equally randomized into two groups. Group I showed the highest degree of pain relief. In both groups, there was a significant reduction in mean baseline pain score, and the mean ECOG performance status improved at the 1-month post-EBRT assessment.

Conclusion
Our analysis showed that both single-session schedules of EBRT with zoledronic acid effectively alleviate painful bone metastases, offering viable options based on individual patient tolerability and compliance.
Temperature Regime of the Air Supply Network of the Air Removal System of Clean Rooms
Authors: Гундарцев М.А. , Рябышенков А.С. , Каракеян В.И. 
Published: September 2024

Исследуется возможность аналитического определения закономерностей изменения температуры воздуха в системе его удаления из чистого помещения микроэлектроники. В качестве основы решения используется уравнение теплового баланса для элементарного отрезка воздуховода при различной технике очистки выбросов. Получены аналитические зависимости температуры удаляемого воздуха на выходе в окружающую среду, определяющей значение термомеханической эксергии выброса и его потенциальную экологическую опасность. Предложены формулы для предварительного определения общей протяженности воздуховода или его участков перед монтажом при их наружной прокладке.
The possibility of an analytical determination of the regularities of the change in air temperature in the system of its removal from a clean room of microelectronics is investigated. As the basis of the solution, the heat balance equation for the elementary segment of the air duct is used with diff erent techniques for cleaning emissions. Analytical dependences of the temperature of the exhaust air at the outlet to the environment determining the value of the thermomechanical exergy of the release and its potential environmental hazard are obtained. Formulas are proposed for the preliminary determination of the total length of the duct or its sections before installation with their external installation.
Automatic Product Identification and Traceability System in the Rubber Industry
Authors: Носенко В.А. , Силаев А.А. , Ефремкин С.И. 
Published: September 2024

Размеры и масштабы реальных сборочных производств увеличиваются, увеличивается также и неэффективность ручных операций сбора данных своевременного реагирования на изменяющиеся параметры, что становится настоящей проблемой. Одним из решений может быть внедрение беспроводных технологий контроля, обеспечивающих реальное представление о повсеместных информационно-измерительных системах, применимых к крупномасштабным сборочным производствам. Контроль качества продукции на производстве в полном объеме возможен только с использованием системы автоматической идентификации и прослеживаемости продукции. Данная работа направлена на изучение основных технологий контроля для проектирования системы идентификации и прослеживаемости. Разработана схема сборки резинотехнического рукава и алгоритм взаимодействия персонала и оборудования. Результаты этого исследования могут помочь инженерам автоматизации в принятии рационального решения по реализации системы автоматической идентификации и прослеживаемости на производстве.
The size and scale actual assembly plants are increasing, and the inefficiency of manual data collection operations and timely response to changing parameters is also increasing, which is becoming a real problem. One of solution is the implementation of wireless monitoring technologies that provide a real view of the ubiquitous information and measurement systems applicable to large-scale assembly plants. Products full quality control in production is possible only with the use of the automatic identification and traceability system. This work is aimed at studying the main control technologies for the identifi cation and traceability systems design. The scheme for assembling a rubber hose and an algorithm for interaction between personnel and equipment has been developed. The results of this research can help engineers in sphere of automation make a rational decision on implementing an automatic identification and traceability system in production.
On Ways to Improve the Information Security of the Radio Communication System of an Unmanned Aerial Vehicle
Authors: Кукушкин С.С. , Кузнецов В.И. , Журавлев С.И. , Титов М.Ю. , Трубиенко О.В. 
Published: September 2024

В работе рассмотрены способы повышения информационной безопасности системы радиосвязи беспилотного летательного аппарата, за счет применения сверхширокополосного приемопередатчика и метода помехоустойчивого кодирования информации, составленного из образов-остатков. Установлены наиболее опасные уязвимости системы радиосвязи беспилотного летательного аппарата. В целях повышения эффективности информационной безопасности средств радиосвязи, предлагается создать мобильный высокопроизводительный радиотехнический комплекс приема и передачи информации на основе применения сверхширокополосного приемопередатчика.
The article describesan approach to comparing software functions using the parameters of their control flow graphs using a bi-directional recurrent neural network. It is established that the neural network is able to develop an internal representation of the graph and metrics, allowing to distinguish the similar features of the algorithms necessary to search for the borrowed code. The most dangerous vulnerabilities of the UAV radio communication system have been identifi ed. In order to improve the efficiency of information security of radio communications, it is proposed to create a mobile high-performance radio engineering complex for receiving and transmitting information based on the use of an ultra-wideband transceiver.
The results of introduction of Sakhalin endemic Lonicera tolmatchevii Pojark. (Caprifoliaceae)
Authors: Шейко В В 
Published: September 2024

В условиях интродукции проведено комплексное исследование редкого эндема острова Сахалин – Lonicera tolmatchevii. Проведен сравнительный анализ итогов испытаний вида на Сахалине и в Москве. Сравнивались сезонные ритмы, зимостойкость. Определена всхожесть семян, описаны особенности роста и развития сеянцев. Проанализированы экологические особенности вида, консортивные связи, конкурентные взаимоотношения в природе, затронут вопрос о происхождении вида.
Under the conditions of introduction, a complex study of a rare endemic of Sakhalin Island - Lonicera tolmatchevii - was carried out. A comparative analysis of the results of tests of the species on Sakhalin and in Moscow has been carried out. Seasonal rhythms, winter hardiness were compared. The germination of seeds is defi ned, features of growth and development of seedlings are described. The ecological features of the species, consortial relations, competitive relationships in nature are analyzed, the question of the origin of the species is touched upon.