bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers to regaining control within a constructivist grounded theory of family resilience in ICU: Living with uncertainty
Authors: Wong Pauline , Liamputtong Pranee , Koch Susan , Rawson Helen 
Published: February 2017

Aims and objectivesTo discuss families’ experiences of their interactions when a relative is admitted unexpectedly to an Australian intensive care unit.BackgroundThe overwhelming emotions associated with the unexpected admission of a relative to an intensive care unit are often due to the uncertainty surrounding the condition of their critically ill relative. There is limited in‐depth understanding of the nature of uncertainty experienced by families in intensive care, and interventions perceived by families to minimise their uncertainty are not well documented. Furthermore, the interrelationships between factors, such as staff–family interactions and the intensive care unit environment, and its influence on families’ uncertainty particularly in the context of the Australian healthcare system, are not well delineated.DesignA grounded theory methodology was adopted for the study.MethodsData were collected between 2009–2013, using in‐depth interviews with 25 family members of 21 critically ill patients admitted to a metropolitan, tertiary‐level intensive care unit in Australia.ResultsThis paper describes the families experiences of heightened emotional vulnerability and uncertainty when a relative is admitted unexpectedly to the intensive care unit. Families uncertainty is directly influenced by their emotional state, the foreign environment and perceptions of being 'kept in the dark', as well as the interrelationships between these factors.ConclusionStaff are offered an improved understanding of the barriers to families’ ability to regain control, guided by a grounded theory of family resilience in the intensive care unit.Relevance to clinical practiceThe findings reveal in‐depth understanding of families’ uncertainty in intensive care. It suggests that intensive care unit staff need to focus clinical interventions on reducing factors that heighten their uncertainty, while optimising strategies that help alleviate it. Families are facilitated to move beyond feelings of helplessness and loss of control, and cope better with their situation.
Evaluation of renal function in a specific population of living kidney donors
Authors: de Souza Rodrigues Thalyta , Amorim de Albuquerque Ana Letícia , de Oliveira Cosme Fillipe Agra , de Oliveira José Ayrton Macedo Guimarães , Magalhães Indalécio , Teles Flávio , Pedrosa André Falcão 
Published: February 2017

SUMMARYBackgroundThe increase in candidates for kidney transplant has led to growth in the number of living donor transplants. Therefore, studies that adequately evaluate the possible long‐term consequences of elective transplant nephrectomy are needed.ObjectiveTo evaluate the possible long‐term adverse effects of transplant nephrectomy on the renal function of living kidney donors.DesignA cross‐sectional study.ParticipantsThirty‐three living kidney donors registered in the transplant programme of a centre in Alagoas, Brazil.MeasurementsDemographic characteristics, anthropometric measures, clinical data and biomarkers (creatinine, eGFR, microalbuminuria, cholesterol and triglycerides) were measured. Creatinine clearance was calculated using the Cockcroft‐Gault and Modification of Diet in Renal Disease formulae.ResultsOf the 33 individuals, 63.63% were female, and the median age was 45 years. Additionally, 24.24% of these individuals had altered blood pressure, 39.39% had altered abdominal circumference (AC) and 36.36% were obese, with a body mass index ≥30. Furthermore, 33.33% of these individuals had elevated triglyceride levels. The average eGFR was 97.33 (33.03–175.9) ml/min/1.73 m2 (CG) and 84.14 (29.4–131) ml/min/1.73 m2 (MDRD). The microalbuminuria level was altered in 12.12% patients.ConclusionKidney donation is unquestionably a safe procedure. However, a better understanding of the long‐term consequences of living donor kidney transplantation is still needed. This knowledge may have important implications for the follow‐up of these patients. Our study has demonstrated a non‐negligible presence of an early marker of glomerular injury and a decrease in the GFR of some patients, thereby reinforcing the proposal for long‐term follow‐up of living kidney donors.
Gastro‐oesophageal reflux disease in 20 dogs (2012 to 2014)
Authors: Muenster M. , Hoerauf A. , Vieth M. 
Published: February 2017

ObjectivesTo describe the clinical features of canine gastro‐oesophageal reflux disease.Materials and MethodsA search of our medical records produced 20 dogs with clinical signs attributable to oesophageal disease, hyper‐regeneratory oesophagopathy and no other oesophageal disorders. The clinical, endoscopic and histological findings of the dogs were analysed.ResultsThe 3‐year incidence of gastro‐oesophageal reflux disease was 0·9% of our referral dog population. Main clinical signs were regurgitation, discomfort or pain (each, 20/20 dogs) and ptyalism (18/20 dogs). Oesophagoscopy showed no (5/20 dogs) or minimal (13/20 dogs) mucosal lesions. In oesophageal mucosal biopsy specimens, there were hyperplastic changes of the basal cell layer (13/20 dogs), stromal papillae (14/20 dogs) and entire epithelium (9/20 dogs). Eleven dogs received omeprazole or pantoprazole and regurgitation and ptyalism improved in eight and pain diminished in six of these dogs within three to six weeks.Clinical SignificanceOur findings suggest that canine gastro‐oesophageal reflux disease is a more common clinical problem than hitherto suspected.
Individual, household, and community level risk factors of stunting in children younger than 5 years: Findings from a national surveillance system in Nepal
Authors: Dorsey Jamie L. , Manohar Swetha , Neupane Sumanta , Shrestha Binod , Klemm Rolf D. W. , West Keith P. 
Published: February 2017

AbstractDespite substantial reductions in recent years in Nepal, stunting prevalence in children younger than 5 years remains high and represents a leading public health concern. To identify factors contributing to the stunting burden, we report multilevel risk factors associated with stunting in 4,853 children aged 6–59 months in a nationally and agroecologically representative random sample from the first year of the Policy and Science for Health, Agriculture, and Nutrition Community Studies, a community‐based observational, mixed‐panel study. Mixed effects logistic regressions controlling for multilevel clustering in the study design were used to examine the association of individual‐, household‐, and community‐level factors associated with stunting. Stunting prevalence was 38% in our sample. After adjustment for potential confounding variables, maternal factors, including maternal height and education, were generally the strongest individual‐level risk factors for stunting, adjusted odds ratio (AOR) = 2.52, 95% CI [1.96, 3.25], short (<145 cm) versus not short mothers; AOR = 2.09, 95% CI [1.48, 2.96], uneducated mothers versus secondary school graduates. Among the household‐ and community‐level factors, household expenditure and community infrastructure (presence of paved roads, markets, or hospitals) were strongly, inversely associated with increased stunting risk, AOR = 1.68, 95% CI [1.27, 2.24], lowest versus highest household expenditure quintile; AOR = 2.38, 95% CI [1.36, 4.14], less developed (lacking paved roads, markets, or hospitals) versus more developed communities. Although most factors associated with stunting are not rapidly modifiable, areas for future research and possible interventions emerged.
A link between LEAFY and B‐gene homologues in Welwitschia mirabilis sheds light on ancestral mechanisms prefiguring floral development
Authors: Moyroud Edwige , Monniaux Marie , Thévenon Emmanuel , Dumas Renaud , Scutt Charles P. , Frohlich Michael W. , Parcy François 
Published: February 2017

Summary

Flowering plants evolved from an unidentified gymnosperm ancestor. Comparison of the mechanisms controlling development in angiosperm flowers and gymnosperm cones may help to elucidate the mysterious origin of the flower.

We combined gene expression studies with protein behaviour characterization in Welwitschia mirabilis to test whether the known regulatory links between LEAFY and its MADS‐box gene targets, central to flower development, might also contribute to gymnosperm reproductive development.

We found that WelLFY, one of two LEAFY‐like genes in Welwitschia, could be an upstream regulator of the MADS‐box genes APETALA3/PISTILLATA‐like (B‐genes). We demonstrated that, even though their DNA‐binding domains are extremely similar, WelLFY and its paralogue WelNDLY exhibit distinct DNA‐binding specificities, and that, unlike WelNDLY, WelLFY shares with its angiosperm orthologue the capacity to bind promoters of Welwitschia B‐genes. Finally, we identified several cis‐elements mediating these interactions in Welwitschia and obtained evidence that the link between LFY homologues and B‐genes is also conserved in two other gymnosperms, Pinus and Picea.

Although functional approaches to investigate cone development in gymnosperms are limited, our state‐of‐the‐art biophysical techniques, coupled with expression studies, provide evidence that crucial links, central to the control of floral development, may already have existed before the appearance of flowers.
Plant, microbial and ecosystem carbon use efficiencies interact to stabilize microbial growth as a fraction of gross primary production
Authors: Sinsabaugh Robert L. , Moorhead Daryl L. , Xu Xiaofeng , Litvak Marcy E. 
Published: February 2017

Summary

The carbon use efficiency of plants (CUEa) and microorganisms (CUEh) determines rates of biomass turnover and soil carbon sequestration. We evaluated the hypothesis that CUEa and CUEh counterbalance at a large scale, stabilizing microbial growth (μ) as a fraction of gross primary production (GPP).

Collating data from published studies, we correlated annual CUEa, estimated from satellite imagery, with locally determined soil CUEh for 100 globally distributed sites. Ecosystem CUEe, the ratio of net ecosystem production (NEP) to GPP, was estimated for each site using published models.

At the ecosystem scale, CUEa and CUEh were inversely related. At the global scale, the apparent temperature sensitivity of CUEh with respect to mean annual temperature (MAT) was similar for organic and mineral soils (0.029°C−1). CUEa and CUEe were inversely related to MAT, with apparent sensitivities of −0.009 and −0.032°C−1, respectively.

These trends constrain the ratio μ : GPP (= (CUEa × CUEh)/(1 − CUEe)) with respect to MAT by counterbalancing the apparent temperature sensitivities of the component processes. At the ecosystem scale, the counterbalance is effected by modulating soil organic matter stocks. The results suggest that a μ : GPP value of c. 0.13 is a homeostatic steady state for ecosystem carbon fluxes at a large scale.
Activation of secondary cell wall biosynthesis by miR319‐targeted TCP4 transcription factor
Authors: Sun Xudong , Wang Chongde , Xiang Nan , Li Xiong , Yang Shihai , Du JianCan , Yang Yongping , Yang Yunqiang 
Published: February 2017

SummaryThe overexpression of miR319 in plants results in delayed senescence, and high levels of miR319‐targeted TCP4 transcription factor cause premature onset of this process. However, the underlying mechanisms of this pathway remain elusive. Here, we found that miR319 overexpression results in a decrease in TCP4 abundance and secondary cell wall formation in the stem. Conversely, constitutive expression of miR319‐resistant TCP4 promotes secondary cell wall formation, indicating that miR319‐mediated TCP4 controls secondary cell wall formation during development. Further analysis revealed that TCP4 might directly bind the promoter of VND7 to activate its expression, which triggers the expression of a VND7 transcriptional network associated with secondary cell wall biosynthesis and programmed cell death and accelerates vessel formation. In addition, the development process gradually increased TCP4 expression. These results suggest that miR319 and its target TCP4 can act as switches that turn on secondary cell wall synthesis and programmed cell death.
Florentine household accounts, fourteenth to seventeenth centuries
Authors: Goldthwaite Richard A. 
Published: February 2017

AbstractThis article calls attention to the personal accounts kept by Florentines for their private affairs. Well over a thousand of these documents survive from the late fourteenth century onwards, and they constitute a source that for the early period probably has no equal for any other city in Europe. Kept according to the highest standards of accounting practice at the time, these accounts document the personal activity of Florentines in the marketplace outside the sphere of their business interests, an area barely adumbrated in the literature on the economic and social history of the city. Of the several functions this activity served, this article concentrates exclusively on just one: the household economy. It explores this subject through a survey of several hundred such accounts with the objective of bringing this source into the extensive literature in Florentine studies on the family, material culture and the economy in general. The discussion emphasizes the importance of change across time and touches on the wider issue of the cultural significance of the accounting practice that brought these documents into existence.
Thinking About Multiword Constructions: Usage‐Based Approaches to Acquisition and Processing
Authors: Ellis Nick C. , Ogden Dave C. 
Published: February 2017

AbstractUsage‐based approaches to language hold that we learn multiword expressions as patterns of language from language usage, and that knowledge of these patterns underlies fluent language processing. This paper explores these claims by focusing upon verb–argument constructions (VACs) such as “V(erb) about n(oun phrase).” These are productive constructions that bind syntax, lexis, and semantics. It presents (a) analyses of usage patterns of English VACs in terms of their grammatical form, semantics, lexical constituency, and distribution patterns in large corpora; (b) patterns of VAC usage in child‐directed speech and child language acquisition; and (c) investigations of VAC free‐association and psycholinguistic studies of online processing. We conclude that VACs are highly patterned in usage, that this patterning drives language acquisition, and that language processing is sensitive to the forms of the syntagmatic construction and their distributional statistics, the contingency of their association with meaning, and spreading activation and prototypicality effects in semantic reference. Language users have rich implicit knowledge of the statistics of multiword sequences.
The impact of bowl size, program setup, and blood hematocrit on the performance of a discontinuous autotransfusion system
Authors: Seyfried Timo F. , Gruber Michael , Streithoff Fabian , Mandle Robert J. , Pawlik Michael T. , Busse Hendrik , Hansen Ernil 
Published: February 2017

BACKGROUNDCell salvage is an essential element in the concept of blood management. Modern devices provide different bowl sizes and sensor‐directed programs to optimally adjust to varying clinical situations.STUDY DESIGN AND METHODSIn an experimental performance study, the discontinuous autotransfusion device XTRA (LivaNova/Sorin) was evaluated using fresh donor blood anticoagulated with heparin 5 U/mL and adjusted to a hematocrit of 10% or 25%, representing orthopedic or cardiac surgery. Test blood was processed with the autotransfusion device XTRA in four different bowls (55 mL, 125 mL, 175 mL, and 225 mL) and in three different program modes (a standard program, an optimized program, and an emergency program).RESULTSProcessing speed increased with bowl size and with the emergency program (range, 6.4‐29.8 mL red blood cells [RBCs]/min). The RBC recovery rate exceeded 90% for all bowls and programs except the 55‐mL bowl with the emergency program. Plasma elimination exceeded 95% for all bowls and programs except the 225‐mL bowl with the emergency and standard programs. Maximal RBC recovery (range, 94.7%‐97.6%) and plasma elimination (range, 98.7%‐99.5%) were obtained with the medium‐sized bowls (125 mL and 175 mL) and the optimized program. Elimination rates for potassium or plasma free hemoglobin were consistently lower than for protein or albumin and were highest for heparin.CONCLUSIONSIncreased hematocrit and RBC recovery rates are obtained with the optimized program Popt with the discontinuous autotransfusion device. The emergency program Pem speeds up the process but leads to RBC loss and reduced plasma elimination rates; therefore, it should be restricted to emergency situations. All four different sized bowls have high performance. Plasma elimination is represented best by protein or albumin elimination rates.
SMALL INTESTINAL INTRAMURAL HEMATOMA SECONDARY TO A MIGRATING WIRE FOREIGN BODY IN A DOG
Authors: Padalkar Mukul , Savage Mason , Cohen Eli B. 
Published: February 2017

AbstractA 12‐year‐old spayed female Labrador retriever was presented for a 5‐day history of vomiting and inappetence. Radiographic findings included poor peritoneal serosal contrast, segmental small intestinal dilation, and multiple linear, metal opaque, intestinal and peritoneal wire foreign bodies. Sonographic findings included septated, hypoechoic, mural expansion of the distal duodenum and jejunum; and an intramural, thin, linear hyperechogenicity with distal acoustic shadowing consistent with a foreign body. Exploratory laparotomy was performed with resection of the affected distal duodenum and proximal jejunum. Histopathology of the excised segment confirmed an intramural hematoma. This case represents an uncommon complication of migrating wire foreign bodies.
Left paralumbar laparoscopic bilateral ovariectomy in mares
Authors: Colbath Aimee C. , Hackett Eileen S. , Lesser Craig S. , Hendrickson Dean A. 
Published: February 2017

AbstractObjectiveTo develop a novel technique for left paralumbar laparoscopic bilateral ovariectomy in standing, sedated mares.Study designProspective descriptive clinical study.AnimalsTwelve client‐owned mares.MethodsHealthy mares with normal ovarian palpation and ultrasonographic appearance were enrolled. Horses were restrained in standing stocks and administered a variable rate infusion of sedation. A left paralumbar bilateral ovariectomy was performed with 1 laparoscopic and 3 instrument portals. Access to the right ovary was facilitated by retracting the descending colon and associated mesentery with a fan retractor. Ovaries were removed with traumatic forceps, and a blunt tip vessel sealing device. A laparoscopic portal within the 17th intercostal space provided good visualization of the right ovary and reduced interference between instrumentation. Complications were recorded during hospitalization. In addition, an owner follow‐up questionnaire was used to determine complications after discharge from the hospital.ResultsLeft paralumbar bilateral ovariectomy was successful in all 12 mares, with a mean surgical time of 76 ± 8 minutes. Postoperative complications occurred in 4/12 (33%) mares and included fever, mild colic, incisional swelling, and azotemia. Complications resolved and mares returned to full activity, with complete owner satisfaction.ConclusionsBilateral ovariectomy can be successfully achieved with minimal morbidity in standing mares with normal ovarian ultrasonographic appearance via left paralumbar laparoscopy.
Antimicrobial Resistance Genes in Pigeons from Public Parks in Costa Rica
Authors: Blanco‐Peña K. , Esperón F. , Torres‐Mejía A. M. , de la Torre A. , de la Cruz E. , Jiménez‐Soto M. 
Published: February 2017

SummaryAntimicrobial resistance is known to be an emerging problem, but the extent of the issue remains incomplete. The aim of this study was to determine the presence or absence of nine resistance genes (blaTEM, catI, mecA, qnrS, sulI, sulII, tet(A), tet(Q), vanA) in the faeces of 141 pigeons from four urban parks in Alajuela, Guadalupe, Tres Ríos and San José in Costa Rica. The genes were identified by real‐time PCR directly from enema samples. About 30% of the samples were positive for genes catI and sulI; between 13% and 17% were positive for qnrS, sulII, tet(A) and tet(Q); and 4% were positive for blaTEM. The mecA and vanA genes were not detected. The average of antimicrobial resistance genes detected per pigeon was 2. Eight different patterns of resistance were identified, without differences in the sampling areas, being the most common pattern 2 (sulII positive samples). During rainy season, the genes more frequently found were sulI and tet(A). In conclusion, the urban inhabiting pigeons tested are currently carrying antimicrobial resistance genes, potentially acting as reservoirs of resistant bacteria and vectors to humans. To the authors’ knowledge, this is the first study carried out on direct detection of resistance genes in the digestive metagenomes of pigeons.
Draft Genome Sequence of Mycobacterium chimaera Type Strain Fl-0169
Authors: Pfaller Stacy , Tokarev Vasily , Kessler Collin , McLimans Christopher , Gomez-Alvarez Vicente , Wright Justin , King Dawn , Lamendella Regina 
Published: February 2017

ABSTRACT

We report here the draft genome sequence of the type strain
Mycobacterium chimaera
Fl-0169, a member of the
Mycobacterium avium
complex (MAC).
M. chimaera
Fl-0169
T
was isolated from a patient in Italy and is highly similar to strains of
M. chimaera
isolated in Ireland, although Fl-0169
T
possesses unique virulence genes.
Genome Sequence of the Basidiomycete White-Rot Fungus
Trametes pubescens
FBCC735
Authors: Granchi Zoraide , Peng Mao , Chi-A-Woeng Thomas , de Vries Ronald P. , Hildén Kristiina , Mäkelä Miia R. 
Published: February 2017

ABSTRACT

Here, we report the genome sequence of the basidiomycete white-rot fungus
Trametes pubescens
FBCC735, isolated from Finland. The 39.67-Mb genome containing 14,451 gene models is typical among saprobic wood-rotting species.
Complete Genome Sequence of Flavobacterium psychrophilum Strain OSU THCO2-90, Used for Functional Genetic Analysis
Authors: Rochat Tatiana , Barbier Paul , Nicolas Pierre , Loux Valentin , Pérez-Pascual David , Guijarro José A. , Bernardet Jean-François , Duchaud Eric 
Published: February 2017

ABSTRACT

We report here the complete annotated genome sequence of
Flavobacterium psychrophilum
OSU THCO2-90, isolated from Coho salmon (
Oncorhynchus kisutch
) in Oregon. The genome consists of a circular chromosome with 2,343 predicted open reading frames. This strain has proved to be a valuable tool for functional genomics.
Complete Genome Sequence of
Herpesvirus anguillae
Strain HVA980811 Isolated in Chiayi, Taiwan
Authors: Wen Chiu-Ming , Liu Ping-Chung , Nan Fan-Hua 
Published: February 2017

ABSTRACT

Herpesvirus anguillae
(HVA), also known as anguillid herpesvirus 1 (AngHV1), is one of the relevant viruses in wild and cultured anguillid eels. Here, the complete genome sequence of strain HVA980811, isolated in Chiayi, Taiwan, is reported. The genotype of the eel herpesviruses in Taiwan is supposed to be identical to the Japanese AngHV1.
Genome Sequences of Three Brucella canis Strains Isolated from Humans and a Dog
Authors: Viana Marcus Vinicius Canário , Wattam Alice Rebecca , Govil Batra Dhwani , Boisvert Sébastien , Brettin Thomas Scott , Frace Michael , Xia Fangfang , Azevedo Vasco , Tiller Rebekah , Hoffmaster Alex R. 
Published: February 2017

ABSTRACT

Brucella canis
is a facultative intracellular pathogen that preferentially infects members of the Canidae family. Here, we report the genome sequencing of two
Brucella canis
strains isolated from humans and one isolated from a dog host.