bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variables determinantes en la disposición al pago por contenidos informativos en Internet: perspectiva de los profesionales
Authors: Marta-Lazo Carmen , Segura-Anaya Ana , Martínez Oliván Natalia 
Published: February 2017

Este artículo analiza el modelo de negocio que permitirá la supervivencia sostenible de proyectos informativos a través del pago por contenidos. Con el objetivo de conocer las posibles variables que influirán en la predisposición al pago por parte de los consumidores, se entrevista a profesionales relevantes del sector de la comunicación, el marketing digital y la empresa periodística. Metodología: entrevistas en profundidad a expertos y análisis bibliográfico de fuentes relacionadas con el pago por contenidos informativos, provenientes tanto de literatura científica, como de informes de organismos destacados en el sector. Resultados. Se constata que el pago por contenidos es una realidad difícil de asumir, pero se propone un posible modelo basado en variables que determinan la disposición al pago por información. Discusión y conclusiones: El modelo de pago por contenidos informativos en Internet está vinculado al valor añadido fundamentado en la calidad en cuatro variables: especialización, diferenciación, exclusividad y accesibilidad.
Modelling a century of soil redistribution processes and carbon delivery from small watersheds using a multi-class sediment transport model
Authors: Wilken Florian , Fiener Peter , Van Oost Kristof 
Published: February 2017

Abstract. Over the last few decades, soil erosion and carbon redistribution modelling has received a lot of attention due to large uncertainties and conflicting results. For a physically based representation of event dynamics, coupled soil and carbon erosion models have been developed. However, there is a lack of research utilizing models which physically represent preferential erosion and transport of different carbon fractions (i.e. mineral bound carbon, carbon encapsulated by aggregates and particulate organic carbon). Furthermore, most of the models that have a high temporal resolution are applied to relatively short time series (< 10 yr−1), which might not cover the episodic nature of soil erosion. We applied the event-based multi-class sediment transport (MCST) model to a 100-year time series of rainfall observation. The study area was a small agricultural catchment (3 ha) located in the Belgium loess belt about 15 km southwest of Leuven, with a rolling topography of slopes up to 14 %. Our modelling analysis indicates (i) that interrill erosion is a selective process which entrains primary particles, while (ii) rill erosion is non-selective and entrains aggregates, (iii) that particulate organic matter is predominantly encapsulated in aggregates, and (iv) that the export enrichment in carbon is highest during events dominated by interrill erosion and decreases with event size.
The Finite-volumE Sea ice–Ocean Model (FESOM2)
Authors: Danilov Sergey , Sidorenko Dmitry , Wang Qiang , Jung Thomas 
Published: February 2017

Abstract. Version 2 of the unstructured-mesh Finite-Element Sea ice–Ocean circulation Model (FESOM) is presented. It builds upon FESOM1.4 (Wang et al., 2014) but differs by its dynamical core (finite volumes instead of finite elements), and is formulated using the arbitrary Lagrangian Eulerian (ALE) vertical coordinate, which increases model flexibility. The model inherits the framework and sea ice model from the previous version, which minimizes the efforts needed from a user to switch from one version to the other. The ocean states simulated with FESOM1.4 and FESOM2.0 driven by CORE-II forcing are compared on a mesh used for the CORE-II intercomparison project. Additionally, the performance on an eddy-permitting mesh with uniform resolution is discussed. The new version improves the numerical efficiency of FESOM in terms of CPU time by at least 3 times while retaining its fidelity in simulating sea ice and the ocean. From this it is argued that FESOM2.0 provides a major step forward in establishing unstructured-mesh models as valuable tools in climate research.
Diabetic Macular Edema Outcomes in Eyes Treated with Fluocinolone Acetonide 0.2 µg/d Intravitreal Implant: Real-World UK Experience
Authors: El-Ghrably Ibraheem , Steel David H.W. , Habib Maged , Vaideanu-Collins Daniela , Manvikar Sridhar , Hillier Roxane J. 
Published: February 2017

Purpose To conduct an observational, multicenter study to evaluate real-world clinical efficacy and safety of the 0.2 µg/day fluocinolone acetonide (FAc) implant in the treatment of patients with chronic diabetic macular edema (DME) in 3 large hospital ophthalmology departments in the United Kingdom. Methods Fluocinolone acetonide implants were inserted into the study eyes following a suitable washout period; phakic eyes received FAc implant following cataract surgery. Follow-up visits took place 2-4 weeks postinjection and then at 3, 6, and 12 months; change in central macular thickness (CMT) from baseline was measured by optical coherence tomography and best-corrected visual acuity (BCVA) was also assessed. Adverse events and changes in intraocular pressure (IOP) were recorded in order to evaluate the safety profile for the FAc implant. Results Improvements in BCVA and CMT were observed from 3 months and sustained for the duration of observation. At 12 months, the overall mean change from baseline CMT was -126 μm and mean increase in BCVA from baseline was 5.1 letters. Increases in IOP following FAc implant were easily managed with IOP-lowering medication. Implant migration into the anterior chamber occurred in 2 eyes where prior vitrectomy had resulted in a posterior capsule defect; this was rectified and resolved. Conclusions The results of this study provide further efficacy and safety profile data for FAc implant treatment of chronic DME in a real-world clinical setting; the FAc implant appears to be a valuable therapeutic approach for patients with chronic DME who have suboptimal response to other treatment options.
Sutureless Extraocular Muscle Biopsy Technique
Authors: Kornhauser Tom , Imtirat Ahed , Levy Jaime , Tsumi Erez 
Published: February 2017

Purpose To describe a simple and novel technique of obtaining an extraocular muscle (EOM) biopsy. Methods Our sutureless method involves obtaining a full-thickness 3-mm EOM specimen using a disposable punch biopsy. Results The procedure was performed successfully, with no worsening of eye movement, muscle weakness, or cosmetic defects postoperatively. The acquired full-thickness specimen was sufficient for analysis. Conclusions This technique to obtain an EOM biopsy allows a straightforward sutureless method, providing an adequate sample for tissue scrutiny.
Impact of Patient-Held Record on Knowledge at 1-Year Follow-Up for Glaucoma Patients: Single-Center Randomized Controlled Trial
Authors: Forbes Marina , Fairlamb Helen , Jonker Leon 
Published: February 2017

Purpose To assess whether provision of a personalized patient-held eye health summary (glaucoma personal record) improves patients’ knowledge of glaucoma at 1-year follow-up. The National Institute for Clinical Excellence has recommended such an approach to ascertain if this may ultimately help slow disease progression. Methods Recruited patients, newly diagnosed with glaucoma conditions, were randomly allocated to receive standard clinical care or an additional glaucoma personal record, detailing the current state of each individual's eye condition. Mann-Whitney U test was applied for comparison of knowledge scores between groups at 1-year follow-up, using a validated questionnaire. Multiple linear regression analysis was applied to detect any factors significantly associated with a difference in glaucoma knowledge. Results A total of 122 patients were recruited; 57 controls and 44 intervention patients were tested for their glaucoma knowledge, equating to 83% retention rate. Out of a maximum available 100% converted score, the median scores were 58% and 53% for the control and intervention arm, respectively (p = 0.85). Regression analysis showed that age (p = 0.015) had a negative association and level of education (p = 0.002) had a positive association with glaucoma knowledge. Conclusions The glaucoma personal record does not impact on a patient's knowledge of glaucoma in either a positive or negative way. Other approaches to improve health literacy among glaucoma patients, particularly for patients who are elderly or have a limited educational background, must be considered to improve patients’ awareness and knowledge of their own condition. Trial registration International Standard Randomized Controlled Trial Number Registry: ISRCTN41306818.
Increase in Physical Activity after Resurfacing Hip Arthroplasty is Associated with Calcar and Acetabular Bone Mineral Density Changes
Authors: Gerhardt Davey M.J.M. , Hannink Gerjon , Rijnders Ton , Van Susante Job L.C. 
Published: February 2017

Purpose Bone preservation is an important advantage of the resurfacing hip arthroplasty (RHA) concept. We hypothesised that patients’ increase in physical activity level after RHA would positively relate with periprosthetic bone mineral density (BMD) changes and thus facilitate bone preservation. Methods BMD-changes were prospectively recorded in 38 patients after RHA. Dual-energy absorptiometry was used to quantify BMD-changes in 6 periprosthetic regions of interest preoperatively, at 6 months, 1, 2 and 3 years postoperative. The effect estimates of patients’ physical activity, according to their Harris Hip Score (HHS) and University of California at Los Angeles (UCLA) Activity Score, on these BMD changes were assessed in linear mixed models. Results The UCLA (coefficient = 0.02 (95% CI, 0.010-0.034); p<0.001) and HHS (coefficient = 0.002 (95% CI, 0.001-0.003); p<0.001) were associated with the BMD in the calcar region. As for BMD changes in the femoral neck only the HHS was associated (coefficient = 0.0006 (95% CI, <0.0001-0.001); p = 0.04). Both the UCLA and the HHS were inversely associated with BMD in the medial acetabular region (UCLA: coefficient = -0.02 (95% CI, -0.038 to -0.007); p = 0.005, HHS: coefficient = -0.002 (95% CI, -0.003 to -0.001), the same accounted for the HHS to BMD-change cranial to the acetabulum (-0.001 [95% CI, -0.0018 to -0.0001]; p = 0.03). For the caudal acetabular and femoral subtrochanteric region no relation with BMD-changes was found. Conclusions The increase in activity scores after RHA was indeed associated with an increase in BMD in the calcar region, however unexpectedly also with a BMD decrease on the acetabular side. Stress shielding from the implant is the most likely causative factor.
Femoral Impaction Allografting for Significant Bone Loss in Revision Hip Arthroplasty
Authors: Goff Thomas A.J. , Bobak Peter 
Published: February 2017

Introduction Femoral impaction bone allografting in revision hip arthroplasty facilitates physiological reconstruction with restoration of bone stock, allowing implantation of a standard cemented femoral component. The purpose of this study was to report our experience in femoral component revision arthroplasty with impaction morsellised cancellous bone allograft using custom impactors and a cemented triple-taper polished stem. Methods Retrospective analysis of all cases of femoral component revision hip arthroplasty with impaction bone grafting undertaken by a single surgeon from 2005 to 2011. Outcome measures included radiographic analysis of stem subsidence over time, graft remodelling and incorporation, and clinical progress. Results We reviewed 47 consecutive hips in 44 patients, mean age 62 years (37-88). Femoral impaction with allograft was performed as either single stage (41 cases) or 2-stage (6 cases) procedures. All patients received a cemented C-stem prosthesis. The mean follow-up period was 5.1 (1.3-9.4) years. The median pre-operative bone defect score was 3 (interquartile range [IQR] 2-3) using the Endo-Klinik classification. Radiological evidence of graft incorporation was observed in 89% (281 of 315 zones) with additional remodelling observed in 33% (103 of 315 zones). The median stem subsidence at 1-year follow-up was 1.1 mm (standard deviation [SD] 1.24 mm, range 0-6 mm). The median Oxford Hip Score at the most recent follow-up was 36.5. To date no femoral component has undergone further revision. Conclusions Encouraging results have been obtained with this technique for the treatment of significant bone loss in revision hip arthroplasty, allowing implantation of a standard prosthesis.
Outcomes after Total Hip Arthroplasty in Young Patients with Osteonecrosis of the Hip
Authors: Swarup Ishaan , Shields Marisa , Mayer Erik N. , Hendow Chelsea J. , Burket Jayme C. , Figgie Mark P. 
Published: February 2017

Background Osteonecrosis of the hip is a clinical, radiographic, and pathologic entity that commonly affects young patients. This study evaluates long-term implant survival and patient-reported outcomes after primary total hip arthroplasty (THA) in patients with osteonecrosis aged 35 or younger. Methods A retrospective study with prospective follow-up was conducted at a major academic medical center. Chart review was performed to identify young THA patients with osteonecrosis, and follow-up surveys were conducted to determine implant survival and patient-reported outcomes. Kaplan-Meier survival analysis was performed to evaluate implant survival, and the hip disability and osteoarthritis outcome score (HOOS) was used to describe patient-reported outcomes. Results The study included 135 patients (204 THAs) with a mean time to follow-up of 14 years. In this group, 10-year implant survival was 86% and 20-year implant survival was 66%. Implant survival was longer in male patients (p = 0.02) and patients that were over the age of 25 at the time of surgery (p = 0.03). The mean HOOS scores at follow-up were 87 for pain, symptoms, and ADLs, and 77 for sports. All HOOS measures were lower in patients that underwent a revision THA, and HOOS-Pain and HOOS-Sport scores were lower in patients that were over the age of 25 at the time of surgery (p<0.05). Conclusions Young patients with osteonecrosis have good implant survival and long-term outcomes after THA. Patient factors and implant characteristics should be considered when predicting implant survival and outcomes after THA in young patients with osteonecrosis.
Outcome of Revision Arthroplasty for Failed Metal-On-Metal Total Hip Replacements; is there a Relation with Metal Ions?
Authors: Iqbal Hafiz J. , Al-Azzani Waheeb A.K. , Jackson-Taylor Esther , Clatworthy Elizabeth , John Alun 
Published: February 2017

Purpose We aimed to assess the early outcome following revision arthroplasty for failed metal-on-metal (MoM) total hip replacements (THR) due to adverse reaction to metal debris (ARMD). Methods We reviewed 106 consecutive revision arthroplasties. Case notes and radiological investigations were reviewed to assess the complications. Oxford Hip Score (OHS) and Euroqol (EQ-5D-3L) scores were used to assess the functional outcome and improvement of quality of life. Results At a mean follow-up of 20 months (12-48 months), the mean OHS was 28.7. Pain improved in 61% patients. A majority of patients were in level 2 for all the EQ-5D-3L dimensions. The overall complication rate was 16%. Survivorship free from further revision for any cause was 94.3% at 48 months. There was no correlation between pre-revision blood metal ions and the final outcome. Conclusions Revision surgery for failed MoM hip replacement due to ARMD is associated with a relatively higher rate of complications and risk of chronic pain. There is poor correlation between serum metal ions and development of ARMD and outcome following revision surgery.
Increase in Safe Zone Area of the Acetabular Cup Using Dual Mobility Cups in THA
Authors: Ohmori Takaaki , Kabata Tamon , Maeda Toru , Kajino Yoshitomo , Taga Tadashi , Hasegawa Kazuhiro , Inoue Daisuke , Yamamoto Takashi , Takagi Tomoharu , Tsuchiya Hiroyuki 
Published: February 2017

Background Dual mobility cup (DMC) inserts reduce the risk of dislocation after total hip arthroplasty (THA). No available research has clearly delineated stability advantages of DMC inserts in primary and revision THA. We investigated: (i) the degree of change in the safe zone of the cup when a DMC insert is used compared to a fixed insert; (ii) the method of selecting candidates for a DMC insert without changing the position of the acetabular (cup) component during revision THA in frequent dislocation cases caused by implant impingement. Methods A model of the pelvis and femur was developed from computed tomography images. The safe zone was defined as the area in the acetabular component, over which conditions for stable range of motion were satisfied. The safe zone was calculated for both a fixed and a DMC insert over a predetermined range of 3-D motion, and the effect of increasing the anteversion position of the femoral component from 5° to 35° was quantified. Results The lowest ratio of the area of the safe zone was about 4.9 at 20° anteverison of the femoral component. Safe zone of DMC inserts zone had increased stability of 10°-15° in both vertical and horizontal directions, compared to fixed inserts. A 5- to10-fold expansion of the safe zone can be expected with the use of DMC insert. Conclusions DMC insert could help to set the acetabular component more accurately in primary and revision THA.
Early Periprosthetic Joint Infection and Debridement, Antibiotics and Implant Retention in Arthroplasty for Femoral Neck Fracture
Authors: Mellner Carl , Eisler Thomas , Knutsson Björn , Mukka Sebastian 
Published: February 2017

Introduction Periprosthetic joint infection (PJI) is a severe complication of hip arthroplasty for femoral neck fractures (FNF). Debridement, antibiotics and implant retention (DAIR) is recommended in early PJI in association with stable implants. Few studies have evaluated the outcome of DAIR in this fragile population. The purpose of this study was to analyse risk factors for PJI and the short-term outcome of DAIR in FNF patients treated with a hip arthroplasty. Methods A consecutive series of 736 patients (median age 81 years, 490 women, 246 men) had been treated with either a total hip arthroplasty or a hemi hip arthroplasty for a displaced FNF at our institution. 33 (4.5%) of the hips developed an early (<6 weeks post operatively) PJI and 28 (3.8%) of these patients were treated according to the DAIR-protocol. Regression analyses were performed to assess risk factors for developing a PJI. Results DAIR eradicated the PJI in 82% (23/28) of patients at a median follow-up of 31 (SD 29.8) months of the infected hips. The logistic regression analysis indicated that 2 or more changes of the primary dressing due to wound bleeding was associated with an increased risk for developing PJI (OR 4.9, 95% 1.5 to 16.1, p = 0.01). Conclusions The short-term success-rate of DAIR was unexpectedly favourable in this fragile patient population; the results being on par with that after PJI in osteoarthritis patients. The need for repeated bandage changes postoperatively indicates an increased risk for PJI and should prompt early surgical intervention.
Screw-Hole Clusters in Acetabular Cups: A Morphological Study of Optimal Positioning of Screw-Holes
Authors: Yin Xinghua , Zhou Yixin , Tang Qiheng , Yang Dejin , Tang Hao , Huang Xingjian 
Published: February 2017

Background Rigid and safe transacetabular screw fixation in total hip arthroplasty (THA) is achieved by pursuing deeper bone stock and avoiding injuries to the neurovascular structures, but these efforts can be restricted by the distribution of screw-holes on cups by the manufacturer. We therefore tried to determine: (i) optimal screw-hole positions on cups to allow anatomical placement of screws; (ii) rationality of the basic 3-screw-hole cluster on commercial cups; and (iii) the optimum method for placing commercial cups in accordance with acetabular anatomy. Methods Periacetabular osseous structure of 64 hips and arterial structures of 50 hips were three-dimensionally reconstructed. Simulated transacetabular screw fixation during THA was performed in these hips with 3 different screw lengths (15, 25, and 35 mm) to define deeper and safer screw trajectories. Screw-hole locations of 7 commercially available cups were measured and matched with the periacetabular anatomy. Results When the cup was placed into the acetabulum at 45° of abduction and 20° of anteversion, the optimal locations of 2 screw-holes on the cups were at 30° and 64° of latitude, with a 35° separation angle. The inversetriangle distribution pattern was safer than the triangle pattern in basic 3-screw-hole-cluster cups. When placing the commercial cups, 5°-10° of anterior rotation can be added to allow better screw trajectories. Conclusions Our study determined optimal screw-hole positions and their distribution pattern on cups. We describe methods to place the commercial cups that are not designed according to acetabular anatomy.
Evaluation of Repair of the Hip Labrum under Simulated Full Weight-Bearing
Authors: Koh Jason L. , Gupta Kavish 
Published: February 2017

Introduction Repairs of labral tears are performed for unstable tears, hip instability, and after detachment concomitant to the treatment of femoroacetabular impingement (FAI), but limited data is known about the strength of repair. This study evaluated the effect of simulated axial weight-bearing on suture anchor based repair of the acetabular labrum. Methods 3 cadaveric pelvises underwent creation of a 1.5 cm anterior-superior labral tear in each hip. The tears were then repaired using 2 suture anchors per hip. Following repair, the hip joint underwent axial cyclic loading to 756 N, and were inspected for separation of the labrum from the acetabulum. The strength of the suture anchor repair was evaluated by testing load to failure, in-line with insertion. Results Upon visual examination, all 6 repairs remained fully intact following loading with no visible gap formation or damage at the repair site. In all cases an arthroscopic probe could not be inserted under the edge of the repair. The mean failure force of the 12 suture anchors, in-line with insertion, was 154 N ± 44 N. Conclusions Acetabular labral suture anchor repairs may be able to immediately withstand the physiological loads of axial weight-bearing. Labral repair may be able to tolerate axial weight-bearing immediately after repair, preserving the strength and integrity of muscles and soft tissues.