bluuebunny/crossref_metadata_2025_split huggingface dataset:
The influence of valence and relationship on children's verification of gossip
Authors: Wan Zhehua , Wang Binjie , Harris Paul L. , Tang Yulong 
Published: October 2024

AbstractGiven that children do not always trust gossip, do they spontaneously check what they are told? We provided 5‐ (N = 32) and 6‐year olds (N = 32) with gossip concerning characters in a cartoon they were watching, and examined whether they verified the gossip by actively re‐watching the relevant episodes. Six‐year olds were more likely to verify gossip than 5‐year olds. When gossip targeted their favourite characters, children were more likely to verify negative when compared with positive gossip. However, when gossip targeted children's disliked characters, they showed no such valence bias. These results indicate that children's verification of gossip increases with age, and they evaluate claims selectively.
Results of Platelet‐Rich Fibrin Application in Pharyngeal Reconstruction After a Total Laryngectomy
Authors: Başkadem Yilmazer Ayça , Aksungur Elif , Çelik Cem , Bayram Avni Akin , Turgut Hüseyin , Dinç Mehmet Emre , Göker Ayşe Enise , Uyar Yavuz 
Published: October 2024

ABSTRACTIntroductionPharyngocutaneous fistula (PCF) is one of the most challenging complications observed after a total laryngectomy. Since the biochemical components of platelet‐rich fibrin (PRF) have well‐known synergistic effects on the healing processes, this study aimed to demonstrate the contribution of PRF application to pharyngeal healing in patients undergoing a total laryngectomy for laryngeal cancer.MethodsThe study compared patients who underwent a total laryngectomy due to laryngeal squamous cell carcinoma and had a PRF membrane placed during the pharyngoesophageal closure with those who did not. There were two groups: PRF‐positive and PRF‐negative. In the PRF‐positive group, after the completion of the total laryngectomy and moving on to the pharyngoesophageal closure stage, along the suture line, PRF material is laid in two pieces in a T‐shape and secured with several sutures. No PRF application was done in the PRF‐negative group. Pharyngeal healing steps (nasogastric feeding, oral feeding, development of a fistula), haemoglobin and albumin values, tumour involvement areas, time to oral intake and length of hospital stay were recorded for all patients.ResultsThis study reviewed the records of 33 patients who underwent pharyngoesophageal closure with PRF application after a total laryngectomy (PRF‐positive group) and 35 patients without PRF application (PRF‐negative group). When comparing patients in terms of developing a PCF, 6% (n = 2) of patients in the PRF‐positive group and 25.7% (n = 9) in the PRF‐negative group developed a fistula. This ratio was significantly higher in the PRF‐negative group (p = 0.027).ConclusionThe application of PRF in pharyngoesophageal reconstruction after a total laryngectomy may strengthen wound healing and reduce the risk of PCF development.Trial RegistrationThis study is a retrospective designed study; therefore, there is no clinical trial registration
Moral challenges and understanding of clinical ethics in Tanzanian hospitals: Perspectives of healthcare professionals
Authors: Kuhumba Shija Kevin , (A.C) Molewijk Bert , Solbakk Jan Helge , Mhando Nandera Ernest , Sævareid Trygve Johannes Lereim 
Published: October 2024

AbstractHealthcare professionals encounter many moral challenges in their daily clinical practice. However, there have been few studies on the subject matter in Tanzania. This study aims to provide an account of moral challenges faced by healthcare professionals in Tanzanian hospitals, their understanding of clinical ethics, and the ethics education they have received. Many participants reported receiving some kind of ethics training through formal education and on‐the‐job training. Some participants understood ethics in healthcare settings as adherence to established laws, regulations, guidelines, procedures, norms, and rules essential in clinical practice. Analysis of the data identified four themes of moral challenges. These challenges are related to 1) decision‐making and communication in clinical practice, 2) scarcity of medical resources and prioritization in clinical practice, 3) withdrawal of curative treatment, and 4) conflicts between professional judgment, religious convictions and adherence to alternative treatments. Based on the findings, we suggest a context‐sensitive form of clinical ethics training to prepare healthcare professionals to recognize and address these moral challenges.
Assessment of the Right Ventricle Function in Patients With Significant Tricuspid Regurgitation: A Review
Authors: Bourg Corentin , Raoult Tristan , Istratoaie Sabina , Beaumont Jérémy , Donal Erwan 
Published: October 2024

ABSTRACTTricuspid regurgitation (TR) is an increasingly prevalent condition, especially in older populations, and presents significant challenges due to its association with right heart failure, hospital admissions, and high mortality rates. The management of TR has evolved, with new percutaneous valve repair and replacement techniques emerging alongside traditional surgical approaches. However, accurately assessing right ventricular (RV) function–a key prognostic factor in TR–remains difficult due to the RV's unique anatomy and sensitivity to loading conditions. Current echocardiographic methods, such as Tricuspid Annular Plane Systolic Excursion (TAPSE), S' wave analysis, and RV fractional area change (FAC), offer valuable insights but have limitations, particularly regarding load dependence and incomplete assessment of RV function. Advances in 3D echocardiography and myocardial strain imaging provide more comprehensive evaluations, yet challenges persist in integrating these measures in routine clinical practice. The review highlights the importance of a multimodal approach to RV assessment in TR patients, considering both the right atrium and pulmonary artery interactions, and explores potential future tools such as myocardial work and dynamic testing to improve prognostic accuracy and patient outcomes.
Evolution and Prognostic Impact of Left Ventricular Myocardial Work Indices After Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis
Authors: Wu Hoi W. , Fortuni Federico , Muzafarova Tamilla , Sarrazyn Camille , Lopez Santi Pilar , Chua Aileen P. A. , Butcher Steele C. , van der Kley Frank , de Weger Arend , Jukema J. Wouter , Bax Jeroen J. , Ajmone Marsan Nina 
Published: October 2024

ABSTRACTPurposeLeft ventricular myocardial work (LVMW) has been shown to better characterize LV function in patients with severe aortic stenosis by correcting LV afterload. The aim of this study was to evaluate the evolution in LVMW indices after transcatheter aortic valve replacement (TAVR) and their prognostic value.MethodsThe following LVMW indices were calculated before and immediately after TAVR in 255 patients (median age 82 years, 51% male): global work index (GWI), global constructive work (GCW), global wasted work (GWW) and global work efficiency (GWE). The study endpoint was all‐cause mortality.ResultsAfter TAVR, LV ejection fraction and LV global longitudinal strain (GLS) did not change significantly (from 56% to 55%, p = 0.470 and from 13.6% to 13.2%, p = 0.068). Concerning LVMW indices, while LV GWW remained unchanged after TAVR (from 247 to 258 mmHg%, p = 0.080), LV GWI, LV GCW, and LV GWE significantly decreased (from 1882 to 1291 mmHg%, p < 0.001, from 2248 to 1671 mmHg%, p < 0.001, and from 89% to 85%, p < 0.001, respectively). During a median follow‐up of 59 [40–72] months, 129 patients died. After correcting for potential confounders (sex, diabetes, renal function, atrial fibrillation, Charlson comorbidity index, and pacemaker implantation post‐TAVR), post‐TAVR LV GLS, GWI, and GCW remained independently associated with all‐cause mortality. However, post‐TAVR LV GWI demonstrated the highest increase in model predictivity.ConclusionIn patients undergoing TAVR, LVMW parameters significantly change after intervention. LV GWI after TAVR showed the strongest association with all‐cause mortality among both conventional and advanced parameters of LV systolic function both pre‐ and post‐TAVR and might enable better risk stratification of these patients after intervention.
INTERSECCIONALIDADE E ORGANIZAÇÕES: UMA ANÁLISE DAS PUBLICAÇÕES DOS ENCONTROS DA ASSOCIAÇÃO BRASILEIRA DE PÓS‐GRADUAÇÃO E PESQUISA EM ADMINISTRAÇÃO
Authors: Elias Maria Ligia Ganacim Granado Rodrigues , Machado Hilka Pelizza Vier 
Published: October 2024

AbstractThe aim of this research is to understand whether gender issues and their intersections have been incorporated into the production of knowledge coming from the meetings of the National Association of Graduate Studies and Research in Administration in Brazil (ANPAD) over the years. A literature review of papers published in the proceedings of ANPAD Meetings (EnANPAD) between 1997 and 2021 was conducted to identify the presence of the thematic axes: gender, sexuality, class, and race. Titles and abstracts of 21,057 papers were analyzed. Were classified 682 papers, in at least one of the axes. The analysis presents quantitative data that shows the volume of scientific work per thematic axis. In addition, the qualitative analysis of the texts identified as intersectional was carried out. The results showed that intersectionality is still not very present in the research presented at EnANPAD, evidencing a weak connection with the social and economic structural context of the country. However, a growing movement, albeit slow, was noted from 2005. The theoretical contribution of this study consists in highlighting an overview of intersectionality in the field of studies in Administration in Brazil. This study can guide future research agendas and Graduation Policies.
Towards decolonial IS: Insights from applying pluriverse and conviviality to analyse a co‐production intervention in Peru
Authors: Jimenez Andrea , Hoefsloot Fenna Imara , Miranda Sara Liliana 
Published: October 2024

AbstractWhile there is a growing interest in applying decolonial approaches within the field of information systems (IS), effective avenues for engagement remain largely unexplored. To this end, our paper introduces a framework focused on decolonial IS research informed by the notions of the pluriverse and conviviality. These concepts emphasise a focus on ontological, epistemological and methodological dimensions, with a strong orientation to justice. We illustrate the application of the framework through a re‐analysis of our own research project, the co‐production of the Metropolitan Water Observatory (MWO) in Lima, Peru. Applying the framework to learn new insights about the MWO, this paper contributes to the IS field by providing a framework from which to examine IS interventions from a decolonial perspective. In addition to advancing theoretical understanding, our framework serves as a valuable resource for scholars navigating the complex landscape of decolonial approaches in IS.
Secukinumab efficacy in patients with hidradenitis suppurativa assessed by the International Hidradenitis Suppurativa Severity Score System (IHS4): A post hoc analysis of the SUNSHINE and SUNRISE trials
Authors: Zouboulis Christos C. , Kyrgidis Athanassios , Alavi Afsaneh , Jemec Gregor B. E. , Martorell Antonio , Marzano Angelo V. , van der Zee Hessel H. , Wozniak Magdalena B. , Martinez Angela Llobet , Kasparek Torben , Bachhuber Teresa , Ortmann Christine‐Elke , Lobach Iryna , Thomas Nicolas , Ravichandran Shoba , Tzellos Thrasyvoulos 
Published: October 2024

AbstractIntroductionThe International Hidradenitis Suppurativa Severity Score System (IHS4) is a validated tool that measures inflammatory lesions, including draining tunnels, in hidradenitis suppurativa (HS).ObjectiveTo evaluate secukinumab efficacy using IHS4 in patients with moderate to severe HS.MethodsData from the SUNSHINE and SUNRISE trials, which assessed subcutaneous secukinumab 300 mg every 2 (SECQ2W) and 4 (SECQ4W) weeks in adults with moderate to severe HS, were analyzed. Assessments included changes from baseline in IHS4 and severity classification up to Week 52; IHS4‐55, IHS4‐75, IHS4‐90 responses (55%, 75% and 90% reduction in IHS4) and concordance between IHS4‐55 and HS clinical response (HiSCR), at Weeks 16 and 52.ResultsIn total, 1084 patients (SECQ2W = 361; SECQ4W = 360; placebo = 363) were analyzed. At Week 16, SECQ2W and SECQ4W demonstrated a numerically higher reduction in IHS4 from baseline versus placebo (adjusted mean [95% CI]: −10.80 [−12.30 to −9.30] and −9.46 [−10.96 to −7.96] vs. −4.92 [−6.43 to −3.41]); the reduction was maintained until Week 52 in both dose regimens. A greater proportion of patients achieved IHS4‐55 with SECQ2W (43.4%) and SECQ4W (39.5%) versus placebo (31.5%) at Week 16, with further improvement at Week 52. Similar trends were observed for IHS4‐75 and IHS4‐90 responses. While no patients had mild disease based on IHS4 (80.7% had severe and 19.3% had moderate HS) at baseline, a greater proportion of patients were categorized as having mild disease at Week 16 in the SECQ2W (25.9%) and SECQ4W (24.0%) groups versus placebo (16.4%); this trend continued up to Week 52 in both dose regimens. Strong concordance (>85%) was observed between IHS4‐55 and HiSCR.ConclusionsBoth SECQ2W and SECQ4W demonstrated efficacy in improving treatment response as measured by IHS4 and reducing disease severity versus placebo at Week 16 and these improvements were sustained through Week 52. These findings support that the dynamic and dichotomous IHS4 can efficiently detect treatment response changes in clinical trial settings.
Soft Tissue Contours at Pontic Sites With or Without Soft Tissue Grafting—A 15‐Year Follow‐Up of a Controlled Clinical Study
Authors: Bienz Stefan P. , Ruales‐Carrera Edwin , Mancini Leonardo , Balmer Marc , Jung Ronald E. , Thoma Daniel S. 
Published: October 2024

ABSTRACTObjectivesTo report on soft tissue contour changes at pontic sites with or without soft tissue grafting over an observation period of 15 years.MethodsFourteen patients received a fixed dental prosthesis (FDP) in the posterior zone in a controlled clinical study and were available at the 15‐year follow‐up. Eight patients received a subepithelial connective tissue graft in the pontic area (test) while six received the FDP without soft tissue grafting (control). Impressions were taken after FDP cementation and at 15 years. Casts were digitized and a profilometric analysis was performed (mean distance) and the pontic height (PH) and ridge width (RW) were analyzed at the mid‐buccal area. A descriptive analysis and Wilcoxon‐Mann–Whitney test was performed (level of significance: 5%).ResultsProfilometric changes (mean distance) from baseline to 15 years amounted to −0.68 mm (test) and to −0.33 mm (control) (p = 0.208), 95% CI for group difference (0.290; −0.750). PH measured −0.47 mm (test) and 0.0 mm (control) (p = 0.079) and RW amounted to −1.05 mm (test) and −0.38 mm (control) (p = 0.138).ConclusionRemodeling of the soft tissue contour at pontic sites of FDPs was evident in both groups, but slightly more accentuated following soft tissue grafting.Clinical SignificanceThis study is the first to report on soft tissue changes at pontic sites over more than 10 years. It investigates whether tissue contour changes with and without soft tissue grafting before the insertion of FDPs. Remodeling of the soft tissue contour at pontic sites was observed over 15 years, with more pronounced changes when soft tissues were augmented with SCTGs before FDP insertion. The volume loss at the augmented site must be considered in relation to the overall tissue changes over long periods. Connective tissue grafts reliably improve shape and esthetics around the pontic unit. Further long‐term studies with more patients are needed to evaluate the initial gains and long‐term performance of these augmentations.
Use of Advanced Platelet‐Rich Fibrin for the Treatment of Multiple Adjacent Mucogingival Recessions: A Technical Report of the Fibrin‐Assisted Soft‐Tissue Promotion Protocol
Authors: Aalam Alexandre‐Amir , Krivitsky Aalam Alina , Yermian Nader , Choukroun Joseph 
Published: October 2024

ABSTRACTObjectivesPlatelet‐rich fibrin (PRF) has had a marked impact on regenerative medicine due to its widespread ability to promote angiogenesis to defective tissues. Particularly in the dental field, evidence from randomized clinical trials has further shown that PRF facilitates greater soft‐tissue regeneration when compared with hard tissues.Clinical ConsiderationsRecently, the fibrin‐assisted soft‐tissue promotion (FASTP) technique has been developed as a means to promote soft‐tissue regeneration of mucogingival recessions utilizing PRF. Within the present case report, a 28‐year‐old male presented with multiple adjacent mucogingival recessions in the maxilla ranging in probing depths (1–3 mm) and gingival recessions (1–5 mm). For optimal regenerative outcomes, the use of advanced PRF (A‐PRF; 1300 RPM for 8 min) has been utilized to enhance regenerative outcomes by fully taking advantage of the low‐speed centrifugation concept (LSCC).ConclusionsThis case report highlights the latest surgical concepts, centrifugation protocols, and use of the LSCC to regenerate multiple adjacent mucogingival recessions in the esthetic zone.
Dimensions of Posterior Implant Restorations Related to Intra‐Coronal Cantilever and Occlusal Forces: An In Vitro Study
Authors: Tzanetou Panagoula , Kourtis Stefanos , Papalexopoulos Dimokritos , Sykaras Nikitas 
Published: October 2024

ABSTRACTObjectiveThe aim of the present study was to investigate the relation of the implant position to the implant crown and analyze the location and magnitude of bite force.Materials and MethodsThe dimensions of 49 posterior implant‐supported restorations were recorded in terms of: 1. implant diameter, 2. crown length, 3. crown width, 4. crown height, 5. occlusal surface of the restoration. The crown/implant height was measured and the distance between the implant center and the restoration center revealed the size of intra‐coronal cantilevers. The occlusal force analysis determined the point and magnitude of loading. Correlation coefficient r was used for the statistical process and statistical control was carried out with the aid of t‐test with minimum level of significance p < 0.05.Results

The mean crown‐to‐implant ratio was 0.9 and in short implants (< 10mm) the ratio was 1.28.

Intra‐coronal cantilever extensions ranged from 2.1 mm to 6.35 mm depending on crown size.

Occlusal loading was identified in cantilever areas of the crown.

Conclusions

Implant center deviates from crown center in 71%–82% of the cases depending on site location.

Implants with non‐ideal position may support a functionally occluding crown.

Clinical SignificanceIntra‐coronal cantilevers are a critical factor to avoid clinical complications and should be taken under consideration both in the planning and fabrication phase of implant restorations.
Is sexual size dimorphism in walleye, Sander vitreus, a driver of seasonal movements in Lake Erie?
Authors: Bihun Christian J. , Faust Matthew D. , Kraus Richard T. , MacDougall Thomas M. , Robinson Jason M. , Vandergoot Christopher S. , Raby Graham D. 
Published: October 2024

AbstractWalleye (Sander vitreus) are a sexually dimorphic species in which females are larger than males in adulthood. Walleye can also exhibit sex‐ and population‐based differences in migration behavior. In Lake Erie, we used acoustic telemetry to test the prediction that female walleye exhibit larger broad‐scale movements than males during the summer and autumn. This prediction was based on the hypothesis that greater foraging in females would be needed to satisfy their higher energy requirements. We quantified movements of males and females from distinct spawning populations from Lake Erie's west and east basins using a lake‐wide grid of acoustic receivers in 2017 and 2018. We found no differences between male and female home range sizes, core range sizes, or distances travelled in either population. Fish length‐at‐tagging was unrelated to the size of a fish's home range or to its distance travelled, contrary to previous predictions about body size as a driver of migration distance in the Lake Erie population. We found that west basin walleye occupied large and indiscrete portions of the lake, but the core range of females extended into the central basin, whereas males were concentrated in the west basin. Walleye originating from the east basin confined their movements primarily to the east basin and showed stronger home range overlap among members of their population than did walleye from the west basin population. Within either population, walleye had more home range overlap with members of the same sex, which likely reflects differences in the migratory tendencies of males and females.
The value of assessing deep disease healing by probe‐based confocal laser endomicroscopy and histology for long‐term prognosis of ulcerative colitis
Authors: Zheng Yue , Zhang Jixin , Wang Jinwei , Li Junxia , Wang Huahong , Tian Yu 
Published: October 2024

AbstractBackground and AimThe benefits of deep disease healing need evaluation by long‐term clinical research in different populations. Confocal laser endomicroscopy (CLE) is a superior method for evaluating deep disease healing.MethodsThis prospective study enrolled ulcerative colitis (UC) patients in clinical remission who underwent colonoscopy, CLE, and histological assessment. Patients were monitored for relapse by patient‐reported outcomes and colonoscopy evaluation of mucosal healing. The ability of different methods of mucosal healing to predict long‐term disease recurrence was assessed using Kaplan–Meier estimation and Cox proportional hazard regression.ResultsForty‐two patients in clinical remission were assessed by colonoscopy. Those with Mayo endoscopic subscores (MES) ≤ 1 were enrolled. The 48‐month recurrence rates in present healing group, assessed by CLE (colonic barrier assessment and ENHANCE index) and by histological examination (Geboes scale), were 20.0%, 26.7%, and 11.1%, respectively, and were significantly lower than absent healing group (P < 0.05). Univariate Cox proportional risk regression analysis in absent of healing disease, determined by the ENHANCE index and Geboes scale, indicated an increased risk of recurrent events, with hazard ratios (HR) of 3.87 (95% CI: 1.18, 12.62) and 8.20 (95% CI: 1.06, 63.30), respectively. Multivariate Cox proportional hazard regression analysis adjusted for the extent of inflammation (E3 or not) showed a significant difference only for the ENHANCE index, with an HR of 3.53 (95% CI: 1.03, 12.10), P = 0.045.ConclusionsDeep disease healing has a lower recurrence rate. The colonic barrier healing assessment, ENHANCE index, and histological Geboes scale have superior long‐term prognostic value for UC patients.