bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of integrated traditional Chinese and Western medicine for acute pancreatitis: A real‐world study in a tertiary teaching hospital
Authors: Deng Lihui , Chen Zhiyao , Zhu Ping , Hu Cheng , Jin Tao , Wang Xinwei , Li Lan , Lin Ziqi , Guo Jia , Yang Xiaonan , Shi Na , Zhang Xiaoxin , Yang Xinmin , Jiang Kun , Ma Yun , Tan Qingyuan , Li Ling , Wang Wen , Huang Wei , Sun Xin , Xia Qing 
Published: September 2024

AbstractAimThis study aimed to evaluate whether integrated traditional Chinese medicine (TCM) and Western medicine (WM) is more effective than WM for acute pancreatitis (AP).MethodsPatients with AP were enrolled and divided into the TCM and WM (TCM&WM) and WM groups according to the therapeutic protocol in real clinical settings. We applied 1:3 propensity score matching, which was to adjust confounding factors. The primary outcome was mortality, whereas the secondary outcomes were organ failure, organ supportive therapies, local complications, hospitalization cost, and length of hospital stay. Sensitivity and subgroup analyses were also performed.ResultsOf 5442 patients with AP, 4691 and 751 were included in the TCM&WM and WM groups, respectively. After PSM, patient baseline characteristics were well balanced. Compared with the WM group (n = 734), the TCM&WM group (n = 2096) had lower overall mortality rate (1.7% vs. 3.4%; risk ratio, 0.482; 95% confidence interval, 0.286–0.810; p = 0.005). The TCM&WM group was associated with lower risk of persistent renal failure, multiple organ failure, and infection, lower utilization of organ supportive therapies, shortened lengths of hospital and intensive care unit stay, and lower hospital costs. Sensitivity analyses showed similar results. Subgroup analysis favored TCM&WM treatment for patients aged < 60 years, with hypertriglyceridic etiology, and with admission interval between 24 and 48 h.ConclusionTCM&WM treatment can achieve lower risks of mortality and organ failure and better economic effectiveness in patients with AP than WM treatment. This study provides a promising alternative of TCM&WM treatment for AP in the real‐world setting.
Methodological and reporting quality of systematic reviews on aesthetics and reconstructive breast surgery: A meta‐research
Authors: Cavalcante Pedro Henrique de Mattos , Pacheco Rafael Leite , Latorraca Carolina de Oliveira Cruz , Oliveira Alex Sandro Moreira Fragoso de , Riera Rachel 
Published: September 2024

AbstractObjectiveTo evaluate the methodological and reporting quality of systematic reviews (SR) of randomized controlled trials on esthetics and reconstructive breast surgery.MethodsMeta‐research study with a broad search strategy was developed to retrieve all relevant systematic reviews. We evaluated the methodological and reporting guidance adopted by these reviews and assessed their adequacy to items from AMSTAR‐2 (methodological quality) and PRISMA 2020 (reporting quality). The protocol of this study was prospectively published in: https://osf.io/preprints/osf/ucpgd.ResultsAfter the selection process, 15 SR were included; eight (60%) referred the use of a methodological guide and five (33.3%) invertedly referred PRISMA as the methodological guide. Reporting guidelines were referred by none of the included systematic review. The median adequacy to PRISMA‐2020 items was 42.9% (Q1 – 38.1%/Q3 – 95.2%) and to AMSTAR‐2 items was 33.3% (Q1 – 23.3%/Q3 – 93.3%) which reflects overall low reporting and methodological quality of included SR. The overall confidence in the results using AMSTAR‐2 framework was critically low in 73.3% of included SR. Although a small number of SR were included, a high correlation between the methodological and reporting quality was observed (Spearmean rho = 0.96, 95% bias‐corrected confidence interval = 0.84 to 0.99).ConclusionMethodological and reposting quality of SR of randomized clinical trials on esthetic or reconstructive breast surgery is poor. Half of the authors referred to the use of valid guidance to plan and conduct their reviews and none of them referred the use of a guidance for reporting their results.
An integrative framework reveals widespread gene flow during the early radiation of oaks and relatives in Quercoideae (Fagaceae)
Authors: Liu Shui‐Yin , Yang Ying‐Ying , Tian Qin , Yang Zhi‐Yun , Li Shu‐Feng , Valdes Paul J. , Farnsworth Alex , Kates Heather R. , Siniscalchi Carolina M. , Guralnick Robert P. , Soltis Douglas E. , Soltis Pamela S. , Stull Gregory W. , Folk Ryan A. , Yi Ting‐Shuang 
Published: September 2024

ABSTRACTAlthough the frequency of ancient hybridization across the Tree of Life is greater than previously thought, little work has been devoted to uncovering the extent, timeline, and geographic and ecological context of ancient hybridization. Using an expansive new dataset of nuclear and chloroplast DNA sequences, we conducted a multifaceted phylogenomic investigation to identify ancient reticulation in the early evolution of oaks (Quercus). We document extensive nuclear gene tree and cytonuclear discordance among major lineages of Quercus and relatives in Quercoideae. Our analyses recovered clear signatures of gene flow against a backdrop of rampant incomplete lineage sorting, with gene flow most prevalent among major lineages of Quercus and relatives in Quercoideae during their initial radiation, dated to the Early‐Middle Eocene. Ancestral reconstructions including fossils suggest ancestors of Castanea + Castanopsis, Lithocarpus, and the Old World oak clade probably co‐occurred in North America and Eurasia, while the ancestors of Chrysolepis, Notholithocarpus, and the New World oak clade co‐occurred in North America, offering ample opportunity for hybridization in each region. Our study shows that hybridization—perhaps in the form of ancient syngameons like those seen today—has been a common and important process throughout the evolutionary history of oaks and their relatives. Concomitantly, this study provides a methodological framework for detecting ancient hybridization in other groups.
A severe head louse (Pediculus humanus capitis) infestation: Timeline, pathogen detection, kdr‐gene screening and morphological anomalies of lice
Authors: Eremeeva Marina E. , Durden Lance A. , Eisenstat Jonathan , Hargrove Brian C. , Mondor Edward B. 
Published: September 2024

AbstractLice are assuming an increasing importance in forensic investigations, given their capacity to provide information about an individual's care. Head louse pediculosis is a frequent condition in school‐age children and can be properly controlled using topical treatments combined with good personal hygiene. Prolonged and chronic infestations may result in more serious outcomes including severe iron deficiency anaemia. We conducted entomological and laboratory investigations of a head louse infestation in a 12‐year‐old girl who experienced severe anaemia and subsequent death. Numerous lice were found postmortem on the head, face and neck of the patient, as well as on bedding and clothing. Analysis of nits on individual hairs determined that the louse infestation had been present for at least 166 days. The lice had some morphological traits characteristic of body lice: the third antennal segment in some specimens was distinctly longer than wide, and the apices of some paratergal plates did not extend into intersegmental membranes, while other morphological features were characteristic of head or body lice. All lice were heterozygous for the T917I kdr genotype, a marker of permethrin resistance. Nineteen (79.2%, 95%CI 59.5%–90.8%) louse DNA samples tested TaqMan positive for Acinetobacter (Moraxellales; Moraxellaceae) sp. Available information and laboratory findings are further discussed regarding their possible contribution to the negative outcome of this case. We stress the impact head louse pediculosis can have on children with limited parental attention, and how severe head louse infestation may serve as warning sign of neglect, and other high‐risk situations.
Endogenous viral elements are targeted by RNA silencing pathways in banana
Authors: Duroy Pierre‐Olivier , Seguin Jonathan , Ravel Sébastien , Rajendran Rajeswaran , Laboureau Nathalie , Salmon Frédéric , Delos Jean‐Marie , Pooggin Mikhail , Iskra‐Caruana Marie‐Line , Chabannes Matthieu 
Published: September 2024

Summary

Endogenous banana streak virus (eBSV) integrants derived from three distinct species, present in Musa balbisiana (B) but not Musa acuminata (A) banana genomes are able to reconstitute functional episomal viruses causing banana streak disease in interspecific triploid AAB banana hybrids but not in the diploid (BB) parent line, which harbours identical eBSV loci. Here, we investigated the regulation of these eBSV.

In‐depth characterization of siRNAs, transcripts and methylation derived from eBSV using Illumina and bisulfite sequencing were carried out on eBSV‐free Musa acuminata AAA plants and BB or AAB banana plants with eBSV.

eBSV loci produce low‐abundance transcripts covering most of the viral sequence and generate predominantly 24‐nt siRNAs. siRNA accumulation is restricted to duplicated and inverted viral sequences present in eBSV. Both siRNA‐accumulating and nonaccumulating sequences of eBSV in BB plants are heavily methylated in all three CG, CHG and CHH contexts.

Our data suggest that eBSVs are controlled at the epigenetic level in BB diploids. This regulation not only prevents their awakening and systemic infection of the plant but is also probably involved in the inherent resistance of the BB plants to mealybug‐transmitted viral infection. These findings are thus of relevance to other plant resources hosting integrated viruses.
A nitrogen‐responsive cytokinin oxidase/dehydrogenase regulates root response to high ammonium in rice
Authors: Li Lun , Jia Letian , Duan Xingliang , Lv Yuanda , Ye Chengyu , Ding Chengqiang , Zhang Yuwen , Qi Weicong , Motte Hans , Beeckman Tom , Luo Le , Xuan Wei 
Published: September 2024

Summary

Plant root system is significantly influenced by high soil levels of ammonium nitrogen, leading to reduced root elongation and enhanced lateral root branching. In Arabidopsis, these processes have been reported to be mediated by phytohormones and their downstream signaling pathways, while the controlling mechanisms remain elusive in crops.

Through a transcriptome analysis of roots subjected to high/low ammonium treatments, we identified a cytokinin oxidase/dehydrogenase encoding gene, CKX3, whose expression is induced by high ammonium. Knocking out CKX3 and its homologue CKX8 results in shorter seminal roots, fewer lateral roots, and reduced sensitivity to high ammonium.

Endogenous cytokinin levels are elevated by high ammonium or in ckx3 mutants. Cytokinin application results in shorter seminal roots and fewer lateral roots in wild‐type, mimicking the root responses of ckx3 mutants to high ammonium. Furthermore, CKX3 is transcriptionally activated by type‐B RR25 and RR26, and ckx3 mutants have reduced auxin content and signaling in roots under low ammonium.

This study identified RR25/26‐CKX3‐cytokinin as a signal module that mediates root responses to external ammonium by modulating of auxin signaling in the root meristem and lateral root primordium. This highlights the critical role of cytokinin metabolism in regulating rice root development in response to ammonium.
Exploring health inequities through the actor‐network theory lens
Authors: Fisher Mar'yana , Tulloch Joanna , Petrovskaya Olga 
Published: September 2024

AbstractSocial theory plays an important role in the nursing discipline and nursing inquiry as it helps conceptually embed nursing in the larger picture of the social world. For example, a broad category of critical theory provides a unique lens for uncovering social conditions of inequity and oppression. Among the sociological theories, actor‐network theory (ANT) is an approach to research and analysis that has recently gained interest among nurse philosophers and researchers. Studies guided by ANT seek to understand phenomena of interest as constituted within the relationships between human and nonhuman actors to understand how care practices are co‐created/enacted and how they can be made more humane. In this paper, we describe the benefits of ANT for examining healthcare access for incarcerated individuals with life‐limiting illnesses accessing palliative care and for people using illicit drugs. We argue that attention to the materiality of care practices can contribute to efforts of advancing health equity for these groups.
The comparative politics of solidarity: Political party discourse across three welfare state regimes
Authors: Luypaert Anouk , Thijssen Peter 
Published: September 2024

AbstractParty political conflict plays an essential role in shaping welfare policies, while they are simultaneously also shaped by these policies. As political parties grapple with the wicked challenges of our times, new forms of solidarity and solidarity conflicts arise across welfare regimes. Despite their significance, these dynamics have not received much recent attention. Our article aims to fill this gap. Through content analysis of party manifestos, we compare the solidarity frames of political parties within and between three distinct welfare regimes—Flanders (Belgium), Sweden, and the United States. Our results confirm our expectations drawn from political feedback literature: while party ideology influences parties' solidarity frame preferences and solidarity conflicts between parties, these preferences and conflicts are also influenced by a welfare regime's societal solidarity norms. Our article highlights the value of analyzing solidarity frames and political solidarity conflicts within welfare‐state regimes to better understand welfare politics and policies.Related ArticlesKönig, Pascal D. 2015. “Moral Societal Renewal or Getting the Country Back to Work: Welfare State Culture as a Resource and a Constraint for Policy Discourse.” Politics & Policy 43(5): 647–78. https://doi.org/10.1111/polp.12130.Mioni, Michele, 2021. “The ‘Good Citizen’ as a ‘Respectable Worker:’ State, Unemployment, and Social Policy in the United Kingdom and Italy, 1930 to 1950.” Politics & Policy 49(4): 913–39. https://doi.org/10.1111/polp.12425.Wagle, Udaya R. 2014. “The Heterogeneity Politics of the Welfare State: Changing Population Heterogeneity and Welfare State Policies in High‐Income OECD Countries, 1980‐2005.” Politics & Policy 41(6): 947–84. https://doi.org/10.1111/polp.12053.
Exponentially localized interface eigenmodes in finite chains of resonators
Authors: Ammari Habib , Barandun Silvio , Davies Bryn , Hiltunen Erik Orvehed , Kosche Thea , Liu Ping 
Published: September 2024

AbstractThis paper studies wave localization in chains of finitely many resonators. There is an extensive theory predicting the existence of localized modes induced by defects in infinitely periodic systems. This work extends these principles to finite‐sized systems. We consider one‐dimensional, finite systems of subwavelength resonators arranged in dimers that have a geometric defect in the structure. This is a classical wave analog of the Su–Schrieffer–Heeger model. We prove the existence of a spectral gap for defectless finite dimer structures and find a direct relationship between eigenvalues being within the spectral gap and the localization of their associated eigenmode. Then, for sufficiently large‐size systems, we show the existence and uniqueness of an eigenvalue in the gap in the defect structure, proving the existence of a unique localized interface mode. To the best of our knowledge, our method, based on Chebyshev polynomials, is the first to characterize quantitatively the localized interface modes in systems of finitely many resonators.
A Social Constructionist Critique of Genetic Determinism
Authors: Ványi Dániel 
Published: September 2024

ABSTRACTRecently genetic determinist claims have reappeared in the explanation of human psychology and to some extent they even made their way into explanations of social phenomena. In this article, I will provide a critical analysis of the genetic determinist discourse from a social constructionist perspective. First, I will examine the meaning of genetic determinism. Then I will shortly introduce the social constructionist perspective generally and it's relevance for analyzing scientific discourses. Next, I will examine the debates about genetic determinism in behavior genetics and sociogenomics and interpret these critically from a social constructionist and deconstructionist perspective. Finally, I will provide an analysis of the main social, ideological, cultural and economic factors that influence the development of genetic determinist ideas: modernity, the legitimation of social hierarchies, neoliberalism and business interests. My conclusion is that the social constructionist perspective is important in the analysis and critique of the genetic determinist discourse.
Wiener densities for the Airy line ensemble
Authors: Dauvergne Duncan 
Published: September 2024

AbstractThe parabolic Airy line ensemble is a central limit object in the KPZ (Kardar–Parisi–Zhang) universality class and related areas. On any compact set , the law of the recentered ensemble has a density with respect to the law of independent Brownian motions. We show
where is an explicit, tractable, non‐negative function of . We use this formula to show that is bounded above by a ‐dependent constant, give a sharp estimate on the size of the set where as , and prove a large deviation principle for . We also give density estimates that take into account the relative positions of the Airy lines, and prove sharp two‐point tail bounds that are stronger than those for Brownian motion. These estimates are a key input in the classification of geodesic networks in the directed landscape. The paper is essentially self‐contained, requiring only tail bounds on the Airy point process and the Brownian Gibbs property as inputs.
A functorial approach to monomorphism categories II: Indecomposables
Authors: Gao Nan , Külshammer Julian , Kvamme Sondre , Psaroudakis Chrysostomos 
Published: September 2024

AbstractWe investigate the (separated) monomorphism category of a quiver over an Artin algebra . We show that there exists an epivalence (called representation equivalence in the terminology of Auslander) from to , where is the category of finitely generated ‐modules and and denote the respective injectively stable categories. Furthermore, if has at least one arrow, then we show that this is an equivalence if and only if is hereditary. In general, the epivalence induces a bijection between indecomposable objects in and noninjective indecomposable objects in , and we show that the generalized Mimo‐construction, an explicit minimal right approximation into , gives an inverse to this bijection. We apply these results to describe the indecomposables in the monomorphism category of radical square zero Nakayama algebras, and to give a bijection between the indecomposables in the monomorphism category of two artinian uniserial rings of Loewy length 3 with the same residue field. The main tool to prove these results is the language of a free monad of an exact endofunctor on an arbitrary abelian category. This allows us to avoid the technical combinatorics arising from quiver representations. The setup also specializes to more general settings, such as representations of modulations. In particular, we obtain new results on the singularity category of the algebras that were introduced by Geiss, Leclerc, and Schröer in order to extend their results relating cluster algebras and Lusztig's semicanonical basis to symmetrizable Cartan matrices. We also recover results on the algebras that were introduced by Lu and Wang to realize groups via semiderived Hall algebras.
Regulatory Role of Collagen XI in the Establishment of Mechanical Properties of Tendons and Ligaments in Mice Is Tissue Dependent
Authors: Ye Yaping , Shetye Snehal S. , Birk David E. , Soslowsky Louis J. 
Published: September 2024

Abstract
Collagen XI is ubiquitous in tissues such as joint cartilage, cancellous bone, muscles, and tendons and is an important contributor during a crucial part in fibrillogenesis. The COL11A1 gene encodes one of three alpha chains of collagen XI. The present study elucidates the role of collagen XI in the establishment of mechanical properties of tendons and ligaments. We investigated the mechanical response of three tendons and one ligament tissues from wild type and a targeted mouse model null for collagen XI: Achilles tendon (ACH), the flexor digitorum longus tendon (FDL), the supraspinatus tendon (SST), and the anterior cruciate ligament (ACL). Area was substantially lower in Col11a1ΔTen/ΔTen ACH, FDL, and SST. Maximum load and maximum stress were significantly lower in Col11a1ΔTen/ΔTen ACH and FDL. Stiffness was lower in Col11a1ΔTen/ΔTen ACH, FDL, and SST. Modulus was reduced in Col11a1ΔTen/ΔTen FDL and SST (both insertion site and midsubstance). Collagen fiber distributions were more aligned under load in both wild type group and Col11a1ΔTen/ΔTen groups. Results also revealed that the effect of collagen XI knockout on collagen fiber realignment is tendon-dependent and location-dependent (insertion versus midsubstance). In summary, this study clearly shows that the regulatory role of collagen XI on tendon and ligament is tissue specific and that joint hypermobility in type II Stickler's Syndrome may in part be due to suboptimal mechanical response of the soft tissues surrounding joints.
Assessing the Thermal Damage Induced by Radiofrequency Ablation for Localized Liver Cancer
Authors: Gupta Pammi Raj , Ghosh Pradyumna 
Published: September 2024

Abstract
Clinical trials are already established for high-temperature treatment of localized cancer, i.e., rise of tissue temperature to more than 55 °C as an effective noninvasive method for the treatment of localized cancer. However, as the computational techniques and capacity have enhanced considerably personalized treatment planning has become a manured tool. In the present investigation, a novel treatment planning framework is being proposed for radio frequency (RF) ablation of cancer tissue based on the tomographic image-based actual model. In patient-specific modeling, different thermal parameters like temperature history during ablation, and thermal damage profile have been virtually determined based on Penne's bioheat transfer model with appropriate boundary conditions. This advancement promises to significantly enhance the capabilities of healthcare practitioners in tailoring personalized treatment strategies for their clinical cases. By leveraging simulation outcomes, clinicians can precisely determine the most effective parameters, such as ablation power and frequency. Unfortunately, the current landscape in India presents a scarcity of specialized medical experts in the field of ablation oncology. Moreover, those who practice in this niche often rely on empirical charts rather than data-driven approaches, highlighting a critical need for increased expertise and the integration of advanced simulation technology to optimize cancer tissue ablation procedures. This real-life patient-specific three-dimensional model-based heat transfer model in a data center-based approach will not only guide the medical practitioner but also a greater number of clinicians can use that. Last but not least, optimizing different operating parameters of RF in this patient-centric approach for accurate treatment has also been discussed.