bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline
Authors: Armenian Saro H. , Lacchetti Christina , Barac Ana , Carver Joseph , Constine Louis S. , Denduluri Neelima , Dent Susan , Douglas Pamela S. , Durand Jean-Bernard , Ewer Michael , Fabian Carol , Hudson Melissa , Jessup Mariell , Jones Lee W. , Ky Bonnie , Mayer Erica L. , Moslehi Javid , Oeffinger Kevin , Ray Katharine , Ruddy Kathryn , Lenihan Daniel 
Published: February 2017

PurposeCardiac dysfunction is a serious adverse effect of certain cancer-directed therapies that can interfere with the efficacy of treatment, decrease quality of life, or impact the actual survival of the patient with cancer. The purpose of this effort was to develop recommendations for prevention and monitoring of cardiac dysfunction in survivors of adult-onset cancers.MethodsRecommendations were developed by an expert panel with multidisciplinary representation using a systematic review (1996 to 2016) of meta-analyses, randomized clinical trials, observational studies, and clinical experience. Study quality was assessed using established methods, per study design. The guideline recommendations were crafted in part using the Guidelines Into Decision Support methodology.ResultsA total of 104 studies met eligibility criteria and compose the evidentiary basis for the recommendations. The strength of the recommendations in these guidelines is based on the quality, amount, and consistency of the evidence and the balance between benefits and harms.RecommendationsIt is important for health care providers to initiate the discussion regarding the potential for cardiac dysfunction in individuals in whom the risk is sufficiently high before beginning therapy. Certain higher risk populations of survivors of cancer may benefit from prevention and screening strategies implemented during cancer-directed therapies. Clinical suspicion for cardiac disease should be high and threshold for cardiac evaluation should be low in any survivor who has received potentially cardiotoxic therapy. For certain higher risk survivors of cancer, routine surveillance with cardiac imaging may be warranted after completion of cancer-directed therapy, so that appropriate interventions can be initiated to halt or even reverse the progression of cardiac dysfunction.
Motivation of User-Generated Content: Social Connectedness Moderates the Effects of Monetary Rewards
Authors: Sun Yacheng , Dong Xiaojing , McIntyre Shelby 
Published: February 2017

The creation and sharing of user-generated content such as product reviews has become increasingly “social,” particularly in online communities where members are connected. While some online communities have used monetary rewards to motivate product review contributions, empirical evidence regarding the effectiveness of such rewards remains limited. We examine the possible moderating effect of social connectedness (measured as the number of friends) on publicly offered monetary rewards using field data from an online review community. This community saw an (unexpected) overall decrease in total contributions after introducing monetary rewards for posting reviews. Further examination across members finds a strong moderating effect of social connectedness. Specifically, contributions from less-connected members increased by 1,400%, while contributions from more-connected members declined by 90%. To corroborate this effect, we rule out multiple alternative explanations and conduct robustness checks. Our findings suggest that token-sized monetary rewards, when offered publicly, can undermine contribution rates among the most connected community members. Data and the online appendix are available at https://doi.org/10.1287/mksc.2016.1022
On Styles in Product Design: An Analysis of U.S. Design Patents
Authors: Chan Tian Heong , Mihm Jürgen , Sosa Manuel E. 
Published: February 2017

Products combine function and form. This paper focuses on product form. We combine state-of-the-art clustering techniques with experimental validation to identify styles (groupings of new product designs of similar form) among the more than 350,000 U.S. design patents granted from 1977 through 2010. Thus we compile, for the first time, a rich data set of styles that can serve as an empirical platform for a rigorous study of the role played by product form in new product development. Building on this platform, we analyze the determinants of “style turbulence”—the year-to-year unpredictability of changes in a style’s prevalence. We find that (i) style turbulence follows a U-shaped relationship with respect to function turbulence (the turbulence of product functions associated with a given style), and (ii) style turbulence increases over time. We discuss the implications of these findings for managing design in new product development. Data and the e-companion are available at https://doi.org/10.1287/mnsc.2016.2653 . This paper was accepted by David Hsu, entrepreneurship and innovation.
Combined phacovitrectomy in the UK: A lean perspective
Authors: Rufai Sohaib R , Alexander Philip , Emsley Elizabeth , Lash Stephen C 
Published: February 2017

Background: Cataract formation is the most frequent complication associated with pars plana vitrectomy (PPV). A growing trend has emerged for surgeons to perform combined phacovitrectomy rather than a two-step approach, even in the absence of cataract. We performed a financial analysis of combined phacovitrectomy for epiretinal membrane (ERM). Methods: Patients who underwent phacovitrectomy for ERM over a three-year period were included in the study. Operating time and cost of theatre time per minute was assessed. Univariate sensitivity analysis was performed to examine the sensitivity of our findings to changes in case duration. Results: Combined phacovitrectomy was performed on 55 eyes. Theatre cost per minute was £14.91 (in addition to £197.49 surgical pack prices). The mean operating time for phacovitrectomy was 48 minutes (range 23–77 minutes) and mean theatre cost was £909 (range 540-1346). The average income for the hospital per combined phacovitrectomy was £914. The conclusion that combined phacovitrectomy represented the more lean approach was robust in our sensitivity analysis. Conclusion: Our findings suggest that phacovitrectomy costs less to healthcare commissioners, yet still leads to a higher income for the hospital due to its higher tariff. Combined phacovitrectomy is the lean approach compared to two-step surgery and should be recommended for all phakic patients with ERM.
Is ultrasound a reliable and precise measure of sternal micromotion in acute patients after cardiac surgery?
Authors: Balachandran Sulakshana , Sorohan Maeve , Denehy Linda , Lee Annemarie , Royse Alistair , Royse Colin , Ali Katijjahbe Mohd , El-Ansary Doa 
Published: February 2017

Background/Aims:There is limited evidence to support the routine prescription of sternal precautions following cardiac surgery, and the effects of dynamic tasks on sternal healing remain unclear. The aims of this study were to determine the reliability of ultrasound as a measure of sternal micromotion and to report the minimal detectable change in the acute cardiac surgery population.Methods:Twenty participants, 3–7 days following cardiac surgery, were recruited. Ultrasound imaging of the sternum was undertaken at rest and during five dynamic tasks, including deep inspiration, cough, upper limb elevation (unilateral and bilateral), and sit to stand. Tasks were repeated three times, and the order randomised. Ultrasound images were captured with a SonoSite M-Turbo device, and two blinded observers used MicroDicom software to measure sternal micromotion. The intra- and inter-observer reliability of the mean ultrasound measures were calculated using intraclass correlation coefficients; precision with the standard error of measurement and calculation of the minimal detectable change.Findings:The intra-observer reliability of the mean ultrasound measures for all tasks ranged from intraclass correlation (3,1) 0.990 to 0.997. The inter-observer reliability ranged from intraclass correlation coefficients (2,1) 0.994 to 0.998. At rest, the standard error of measurement was 0.05 mm and the minimal detectable change was 0.14 mm for both the lateral and antero–posterior motion of the sternal edges.Conclusions:Ultrasound is a reliable and precise measure of sternal micromotion in the acute cardiac surgery population. The results of this study suggest that future research exploring the effects of exercise and functional tasks on the healing sternum using ultrasound is warranted to better inform post-operative management and intervention for this patient population.
Qualitative research. Part 2: Methodologies
Authors: Nicholls David 
Published: February 2017

Background: There are still many practitioners, academics and researchers who are bemused by the principles and practices of qualitative research. The second paper in this three part series on qualitative research explores the important question of research methodologies. Content: Focusing on four of the more common methodologies—phenomenology, grounded theory, ethnography and discourse analysis—the article shows how each represents a distinctively different view of reality (a feature of qualitative research that was unpacked in the first article in the series). Conclusions: These methodologies are then used to highlight some of the fundamental methodological differences between quantitative and qualitative research. Having set down these principles, I move on, in the third article, to discuss qualitative methods of data collection and analysis.
Local regularity and compactness for the p-harmonic map heat flows
Authors: Misawa Masashi 
Published: February 2017

Abstract
We study a geometric analysis and local regularity for
the evolution of

p

{{p}}

-harmonic maps, called

p

{{p}}

-harmonic map heat flows.
Our main result is
to establish a criterion for a uniform local regularity estimate
for regular

p

{{p}}

-harmonic map heat flows,
devising some new monotonicity-type formulas
of a local scaled energy.
The regularity criterion obtained is almost optimal, comparing with
that of the corresponding stationary case.
As application we show a compactness of
regular

p

{{p}}

-harmonic map heat flows with energy bound.
Theoretical analysis of a water wave model with a nonlocal viscous dispersive term using the diffusive approach
Authors: Goubet Olivier , Manoubi Imen 
Published: February 2017

Abstract
In this paper, we study the following water wave model with a nonlocal viscous term:

u_{t}+u_{x}+\beta u_{xxx}+\frac{\sqrt{\nu}}{\sqrt{\pi}}\frac{\partial}{%
\partial t}\int_{0}^{t}\frac{u(s)}{\sqrt{t-s}}\,ds+uu_{x}=\nu u_{xx},

where

{\frac{1}{\sqrt{\pi}}\frac{\partial}{\partial t}\int_{0}^{t}\frac{u(s)}{\sqrt{%
t-s}}\,ds}

is the Riemann–Liouville half-order derivative.
We prove the well-posedness of this model using diffusive realization of the half-order derivative,
and we discuss the asymptotic convergence of the solution.
Also, we compare our mathematical results with those given in [5] and [14] for similar equations.
Effect of sous-vide technique on fatty acid and mineral compositions of beef and liver from Bonsmara and non-descript cattle
Authors: Falowo Andrew Bamidele , Muchenje Voster , Hugo Arno 
Published: February 2017

Abstract
This study examined the fatty acid and mineral compositions of raw and cooked beef and liver from Bonsmara (BD) and non-descript (ND) cattle, raised on natural pasture. Samples were collected from 80 cows and thermal-processed at 65°C for 120 minutes and 85°C for 60 minutes using sous-vide techniques, and then analysed for fatty acid and mineral compositions. The results did not show differences in individual fatty acid composition of meat samples between the breed (P>0.05). However, the raw beef sample had higher content of monounsaturated fatty acids (MUFA , 40.22% ± 3.79 ND, 42.53% ± 2.39 BD) and lower content of polyunsaturated fatty acids (PUFA , 11.02% ± 5.47 ND, 10.13% ± 6.73 BD) than liver (MUFA , 20.11% ± 4.76 ND, 21.08% ± 2.46 BD; PUFA , 30.73% ± 5.20 ND, 31.11% ± 2.37 BD) (P<0.05). The PUFA /MUFA and n-6/n-3 ratios, atherogenicity and desaturase indices were comparable between breeds, but higher in beef than liver. The total percentage of saturated fatty acid, MUFA and PUFA retained after cooking were numerically higher in liver than in beef (P>0.05). The results further revealed higher contents of Na, Mg, and Zn in raw beef than liver. However, the content of Na, Mg, and Zn in the beef and liver were not significantly (P>0.05) affected after cooking. Based on the PUFA proportion of the total lipids in beef (11.02%) and liver (31.11%) and n-6/n-3 PUFA ratio in beef (2.54) and liver (1.34), consumption of liver and beef from cattle raised on pasture could be beneficial to human health. Additionally, application of sous-vide technique can be used to minimize the nutritional losses in beef and liver.
Supplementing lactation diets with herbal extract mixture during summer improves the performance of sows and nursing piglets
Authors: Liu Wen-Chao , Yun Hyeok-Min , Pi Seung-Ho , Kim In-Ho 
Published: February 2017

Abstract
A total of 45 Landrace × Yorkshire multiparous sows were used to evaluate the effect of dietary herbal extract mixture (Scutellaria baicalensis and Lonicera japonica, HEM) supplementation in lactating sows under heat stress. Sows were randomly allotted to 1 of 3 dietary treatments: 1) CON, basal diet; 2) TRT 1, basal diet with 5 g/d HEM; 3) TRT 2, basal diet with 10 g/d HEM. During lactation, dietary HEM supplementation linearly increased (P<0.05) the average daily feed intake (ADFI) and linearly decreased (P<0.05) backfat loss. The digestibility of dry matter (DM) was increased after farrowing (linear, P<0.05; quadratic, P<0.05) and weaning (linear, P<0.05) by HEM supplementation. Furthermore, HEM treatment led to a lower (linear, P<0.01) serum cortisol level. In addition, administration of HEM improved (linear, P<0.05) the piglets weaning weight and overall average daily gain (ADG) during suckling period. Meanwhile, on day 7 and 14 after birth, the fecal score of piglets was decreased (linear, P<0.01) by HEM supplementation. Taken together, under high ambient temperatures, inclusion of HEM to lactation diets could improve the feed intake, digestibility of DM, piglets weaning weight and ADG, while decreasing backfat loss, serum cortisol level, as well as the diarrhea of piglets.
Apoptosis in chicken ovarian follicles following in vitro exposure to TCDD, PCB 126 and PCB 153
Authors: Antos Piotr A. , Hrabia Anna , Gdula Anna , Sechman Andrzej 
Published: February 2017

Abstract
The study was conducted in order to compare the in vitro effect of 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD), 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) and 2,2′,4,4′,5,5′-hexachlorobiphenyl (PCB 153) on the number of apoptotic cells and the activity of caspase-3 in chicken ovarian follicles. The ovarian stroma, white (WF) and yellowish (YF) prehierarchical follicles and fragments of the theca and granulosa layers of the 3 largest preovulatory follicles (F3-F1) were in vitro exposed to TCDD (10 nM), PCB 126 (10 nM) and PCB 153 (10 μM) for 24 h. After incubation the number of apoptotic cells and caspase-3 activity were determined by TUNEL method and fluorometric assay, respectively. PCB 126 and PCB 153 increased the number of apoptotic cells in the ovarian stroma while TCDD and PCB 126 elevated it in the WF follicles. Under the control conditions, caspase-3 activity steadily increased along with maturation of the follicles, reaching the highest level in the theca layer of the F1 follicle. The activity of this enzyme in the granulosa layer of F3-F1 follicles was on average 60% lower in comparison to the stroma. Exposure to TCDD elevated caspase-3 activity in prehierarchical follicles and in the granulosa layer of F2 and F1 preovulatory follicles. On the contrary, PCB 126 exerted a suppressive effect on caspase-3 activity in the WF follicles and the granulosa layer of the F2 follicle, and PCB 153 in the theca layer of F2 and F1 and the granulosa layer of the F3 follicle. In conclusion, the results indicate that TCDD and PCBs affect apoptosis in chicken ovarian follicles and in consequence may disrupt follicle development.
Factors affecting the freezing point of milk from Polish Holstein-Friesian cows
Authors: Otwinowska-Mindur Agnieszka , Ptak Ewa , Grzesiak Agnieszka 
Published: February 2017

Abstract
The objective of this study was to estimate the influence of lactation number, month of milk sampling, lactation stage and herd size on the freezing point of milk of Polish Holstein‑Friesian cows. Data comprised 4,719,787 milk samples from the first seven lactations of 752,770 Polish Holstein- Friesian cows. Milk freezing point (MFP), milk yield, and fat and protein content were analyzed. The mean MFP of milk samples (-0.5326°C) as well as more than 92% of all milk samples did not exceed the quality limit for the freezing point of cows′ raw milk, which, following Polish standards, was taken to be -0.52°C. The freezing point of milk samples, milk yield, fat and protein content were highly significantly affected by all examined factors: month of sampling, successive lactations, stage of lactation, and herd size. MFP was lowest in milk samples taken from January to March, and highest in samples from November to December. MFP increased with lactation number. Mean MFP decreased with time within lactation, except the first stage (5-35 days in milk). Generally, MFP was highest in small herds (up to 9 cows) and lowest in large herds (more than 150 cows).
An Experiment on Radio Location of Objects in the Near-Earth Space with VLBI in 2012
Authors: Nechaeva M. , Antipenko A. , Bezrukovs V. , Bezrukov D. , Dementjev A. , Dugin N. , Konovalenko A. , Kulishenko V. , Liu X. , Nabatov A. , Nesteruk V. , Pupillo G. , Reznichenko A. , Salerno E. , Shmeld I. , Shulga O. , Sybiryakova Y. , Tikhomirov Yu. , Tkachenko A. , Volvach A. , Yang W.-J. 
Published: February 2017

AbstractAn experiment on radar location of space debris objects using of the method of VLBI was carried out in April, 2012. The radar VLBI experiment consisted in irradiation of some space debris objects (4 rocket stages and 5 inactive satellites) with a signal of the transmitter with RT-70 in Evpatoria, Ukraine. Reflected signals were received by a complex of radio telescopes in the VLBI mode. The following VLBI stations took part in the observations: Ventspils (RT-32), Urumqi (RT-25), Medicina (RT-32) and Simeiz (RT-22). The experiment included measurements of the Doppler frequency shift and the delay for orbit refining, and measurements of the rotation period and sizes of objects by the amplitudes of output interferometer signals. The cross-correlation of VLBI-data is performed at a correlator NIRFI-4 of Radiophysical Research Institute (Nizhny Novgorod). Preliminary data processing resulted in the series of Doppler frequency shifts, which comprised the information on radial velocities of the objects. Some results of the experiment are presented.
Peculiarities and Variations in the Optical Spectrum of the RV Tauri-type Star R Sct
Authors: Kipper Tõnu , Klochkova Valentina G. 
Published: February 2017

Abstract
We analyzed some new high resolution optical spectra of the semiregular RV Tauri-type star R Sct. Fundamental parameters were found to be T
eff = 4500 K, log g = 0.0 and ξ
t = 4.0 km s−1. The results of chemical analysis show that R Sct is a metal-poor star with [Fe/H]≈ −0.5. The carbon content with respect to iron is significantly larger than in the Sun, [C/Fe]=0.84, but there is an evident deficiency of heavy elements. We found no tight correlation of the chemical abundances on the condensation temperatures of elements. This means that in R Sct the depletion by condensation into dust does not work, with possible exception of Ca and Sc. The luminosity derived from the Hipparcos parallax corresponds to a tip of the red-giant branch or slightly above it. Thus it is possible that R Sct evolved off the early-AGB when it has not yet experienced the third dredge-up in thermal pulses, or it is still located on AGB. The peculiarities of spectral features (emissions, line-splitting) and the complicated time-variable radial velocities were also studied.
Seven-Color Photometry and Classification of Stars in the Direction of Open Cluster M29 (NGC 6913) in Cygnus
Authors: Milašius K. , Boyle R. P. , Vrba F. J. , Janusz R. , Straižys V. , Černis K. , Laugalys V. , Zdanavičius K. , Zdanavičius J. , Kazlauskas A. , Smilgys R. 
Published: February 2017

Abstract
Magnitudes and color indices in the Vilnius seven-color system were determined for 1752 stars down to V = 19.5 mag in the direction of the open cluster M29 (NGC 6913). The region is centered at RA = 20:24, DEC = +38:30 (J2000) and covers an area of 1.5 sq. deg. The photometric data are used to classify about 70% of stars in spectral and luminosity classes and peculiarity types.
Seven-Color Photometry and Classification of Stars in the Vicinity of the Dark Cloud TGU H994 (LDN 1399, 1400 and 1402)
Authors: Čepas V. , Zdanavičius J. , Zdanavičius K. , Straižys V. , Laugalys V. 
Published: February 2017

Abstract
The results of CCD photometry in the seven-color Vilnius system are given for 727 stars down to V ~ 17 mag in a 1.5 square degree field in the region of dark cloud TGU H994 P1 (or LDN 1399, LDN 1400 and LDN 1402) in Camelopardalis. Using the intrinsic color indices and photometric reddening-free Q-parameters, two-dimensional spectral types for 73% of stars are determined.
A New Empirical Metallicity Calibration for Vilnius Photometry
Authors: Bartašiūtė S. , Raudeliūnas S. , Sperauskas J. 
Published: February 2017

Abstract
We present a new calibration of the seven-color Vilnius system in terms of [Fe/H], applicable to F–M stars in the metallicity range −2.8 ≤[Fe/H]≤ +0.5. We employ a purely empirical approach, based on ~1000 calibrating stars with high-resolution spectroscopic abundance determinations. It is shown that the color index P–Y is the best choice for a most accurate and sensitive abundance indicator for both dwarf and giant stars. Using it, [Fe/H] values can be determined with an accuracy of ±0.12 dex for stars of solar and mildly subsolar metallicity and ±0.17 dex for stars with [Fe/H] < −1. The new calibration is a significant improvement over the previous one used to date.
Physical Alternative to the Dark Energy Paradigm
Authors: Sapar A. 
Published: February 2017

Abstract
The physical nature of the presently dominating enigmatic dark energy in the expanding universe is demonstrated to be explainable as an excess of the kinetic energy with respect to its potential energy. According to traditional Friedman cosmology, any non-zero value of the total energy integral is ascribed to the space curvature. However, as we show, in the flat universe the total energy also can be different from zero. Initially, a very small excess of kinetic energy originates from the early universe. The present observational data show that our universe has probably a flat space with an excess of kinetic energy. The evolutionary scenario shows that the universe presently is in the transitional stage where its radial coordinate expansion approaches the velocity of light. A possibility of the closed Bubble universe with the local Big Bang and everlasting expansion is demonstrated. Dark matter can be essentially contributed by the non-relativistic massive neutrinos, which have cooled to very low temperatures and velocities thus favoring the formation of the observed broad equipotential wells in galaxies.