bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PROBIOTIK PADA RESPON IMUN
Authors: Djunaedi Djoni 
Published: January 2017

Probiotics (â€œfor lifeâ€) is a live microbial feed supplement or defined as mono- or mixed cultures of live microorganismsÂ which when administered in adequate amounts confer Â a health benefit to the host by improving its microbial balance.Â Common descriptives for probiotics include â€œfriendlyâ€, â€œbeneficialâ€ or â€œhealthyâ€ bacteria. Â Under natural conditions aÂ protective gut microflora develops and there is no Â need for probiotics supplement, but under rather un-natural conditionsÂ such like intestinal infections, post antibiotic treatment syndromes, pseudomembranous colitis, the probiotics preparationsÂ are needed. The beneficial effects of probiotics inthe host are promotion of the gut maturation and integrity, antagonismsÂ against pathogens and immune modulation. Beyond those, the microflora seems to play a significant rolein diet inducedÂ superinflammation, mucosal immune system, neuroendocrine regulation, immunoglobulin production, macrophages factorÂ restoration, apoptosis stimulation, lymphocyte function modulation, cytokine release, mucin production, intestinal immuneÂ homeostasis and inflammation prevention. However, many studies proved that probiotics have â€œupregulation and down-regulationâ€ effects on immune system of the host.
AKURASI METODE RADIOKOLLOID DAN BLUE DYEDALAM MENDETEKSI LIMFONODI SENTINEL PADA KANKER PAYUDARA STADIUM DINI
Authors: Yueniwati Yuyun , Yulisa N. Diana , Iskandar Arief 
Published: January 2017

reast cancer incidence varies in many countries but in general increases. This research aimed to find Â out the accuracyÂ of radiocolloid (lymphoscintigraphy and gamma probe) as well as blue dye method in detecting sentinel node in the earlyÂ stage breast cancer. Diagnostic examination was conducted on 163 nodes of 14 patients cross sectionally, comparing theÂ accuracy of radiocolloid and blue dye methods with Â histopathologic method as the gold standard. Subject characteristicsÂ were female, aged 39-53, mostly menopause, multipara and breast-feeding. Primary tumors were mostly found in theÂ right, upper lateral quadrant, T2, histopathologic results showed that all were of invasive ductal carcinomas and 71.4%Â cases were lymphatic emboli. The detection of sentinel node with lymphoscintigraphy had 81.8% accuracy,sensitivityÂ 90.4%, specificity 73.2%, NPV 98.1%, false-negative1.8% and kappa value 0.37. Detection using gamma probe resultedÂ in 79% accuracy, sensitivity 90.4%, specificity 67.6%, NPV 97.9%, false-negative 2% and kappa value 0.31.
KADAR MDA DAN RASIO GSH/GSSH PADA KEHAMILAN NORMAL,PREEKLAMPSIA BERAT DAN EKLAMPSIA DI MALANG
Authors: Candra Siti , Widodo M Aris , Suwarto Soetomo , Muliartha G I Ketut 
Published: January 2017

Preeclampsia is marked by vasospasme, increasing peripheral vascular resistance and permeability, endothelial cell andÂ reducing organ perfusion. It occurs because of the increasing of lipid hydroperoxides. The uncontrolled production of lipidÂ hydroperoxides causes oxidative stress and destroyscell integrity. Oxidative stress condition expressthe increasingÂ oxidant and decreasing antioxidant. One of the antioxidant is GSH that is used to neutralize the increasing ofÂ Malondialdehyde (MDA) level. The objective of this study was to see the difference of MDA content and GSH. GSSG ratioÂ between the normal pregnancy, preeclamsia and eclampsia. This study was cross sectional study. The samples were 36Â blood plasma consisted of 12 normal pregnancy, 12 preeclampsia and 12 eclampsia before birth. The bloodplasma, wasÂ measured for its MDA level and the GSH/GSSH ratio.The result showed that the level of MDA of plasma in preeclampticÂ and eclamptic pregnancy were higher than normal pregnancy p=0.000, due to lipid peroxidation resulted Â from increasedÂ production of lipid hydroperoxides on preeclamptic Â and eclamptic pregnancy.
AKTIVASI SPONTAN SEL T LIMFOSIT MENCIT YANG MENGALAMI DEFISIENSI IL2RÎ²
Authors: Endharti Agustina Tri 
Published: January 2017

Homologous recombination applied to alter specific Â endogenous gene, referred as gene targeting, provides the highestÂ level of control over product mutation in cloned genes. In this experiment we showed that by using gene targeting a knockÂ out mutation in IL-2RÎ² gene could be generated. The findings of this study indicated that mice lacking the Interleukin-2Â receptor Î² chain (IL2RÎ²-/-) had spontaneously activated.T cells. In this study, we investigated abnormal expansion ofÂ activated T cells which showed high level of CD69. Â These findings suggest that the IL2RÎ²-/-Â mice may serve as animalÂ model for autoimmune diseases and that the accumulation of activated T cell in the future could be usedin clinical settingÂ to cure the diseases.Â Keywords:T cells, (IL2RÎ²-/-), autoimmune
PENGARUH LINGKUNGAN KERJA PERAWAT TERHADAP PELAKSANAAN PRAKTEK KEPERAWATAN DI RUMAH SAKIT UMUM Dr. SAIFUL ANWAR MALANG TAHUN 2006
Authors: Putra Kuswantoro Rusca , Hamid Achir Yani S. , Mustikasari Mustikasari 
Published: January 2017

The implementation of nursing practice is related tonurses' working environment. The working environment componentsÂ consist of leadership, culture and management; control over workload; control over practice; and adequate source. TheÂ purpose of this study is to identify any correlation between the nurses work environment with the implementation ofÂ nursing practice. The research was conducted in IRNA(Inpatients Ward) I and of IRNA II RSU Dr. Saiful Â Anwar on MayÂ 1stuntil 20th, 2006. Correlation was chosen as the research design using cross sectional study on 196 nurses with twoÂ instruments: nurses' work environment, and implementation of nursing practice. The result based on analysis withÂ regression linier indicates that there is a significant correlation between working nurse environment(leadership, cultureÂ and management; control over workload; control overpractice; and adequate source) with the implementation of nursingÂ practice (p < 0.05) and control over practice is the biggest sub variable that influences the implementation of nursingÂ practice(B=1.302). In conclusion, the nurseâ€™s working environment influences implementation of nursingpractice inÂ hospital.Â Keywords:Work environment, Implementation of nursing practice
PENGEMBANGAN DIAGNOSIS TUBERKULOSIS PADA HEWAN KESAYANGAN ANJING MENGGUNAKAN ANTIGEN SPESIFIK Mycobacterium tuberculosisESAT-6 DAN CFP-10
Authors: Tjahajati Ida , Asmara Widya , Soebono Hardyanto 
Published: January 2017

Early diagnosis is one of the important methods to Â control tuberculosis because this disease is zoonotic which easilyÂ spread through the air. Early detection of tuberculosis in dog is also very important since dog as petanimal have aÂ potency to transfer the disease to human or other animals. The discovery of two specific M.tuberculosisantigens,Â ESAT06 and CFP-10, provide the opportunity to developa specific diagnostic kit for tuberculosis by using ELISA basedÂ on the secretion of IFN-Î³. The development of a tuberculosis diagnostic kit based on this molecular biology andÂ immunological method would provide a good alternative method to detect tuberculosis specially, accurately as early asÂ possible. The result of this experiment would provide contribution for the development of health science and technology,Â especially in the eradication of tuberculosis.Â Keywords: diagnosis, tuberculosis, ESAT-6, CFP-10, interferon-gamma.
EFEK ANTIMIKROBA DARI EKSTRAK BIJI DAN DAUN MIMBA (Azadirachta indica A. Juss.) TERHADAP PERTUMBUHAN Malassezia globosa
Authors: Hastuti Utami Sri 
Published: January 2017

Neem (Azadirachta indica A. Juss.) is a sort of a useful plant especially for health. Antimicrobial compounds in seed andÂ leaf of neem especially are: azadirachtin, fenol, quinon, alkaloid, nimbin, nimbidin and gedunin. Malassezia globosa is aÂ pathogenic yeast that cause dandruff on head skin. Â This research is done on behalf to know: 1) the inhibition of neemÂ seed extract to the growth of M. globosa in vitro;2) the difference of the effect of neem seed extract concentration to theÂ growth inhibition of M. globosa in vitro; 3) the Â inhibition of neem leaf extract to the growth of M.globosa; 4) theÂ difference of the effect of leaf neem extract concentration to the growth inhibition of M. globosa in Â vitro. Neem seed andÂ neem leaf extract made in some sort of concentration, i.e: 10%, 20%, 30%, 40%, 50%, 60%, 70%, 80%, 90%, and 100%.Â The growth inhibition of M. globosa was measured by Â measuring the inhibition zone diameter of the yeastgrowth onÂ Sabouroudâ€™s Dextrosa Agar.
PENINGKATAN KUALITAS SPERMATOZOA PADA PROSES PEMISAHAN SPERMATOZOA DENGAN SENTRIFUGASI GRADIEN DENSITAS PERCOLL MELALUI PEMBERIAN FOSFOLIPID
Authors: Rumende Rooije R.H. , Kalim Handono , Widodo M Aris , Djati Moch Sasmito 
Published: January 2017

The separation of X and Y spermatozoa can be conducted by using Percoll Gradient Density Centrifugation(SGDP)Â method. It is, easy, valid, cheap and applicable method for developing made-insemination. Although it Â has often beenÂ applied in sexing the spermatozoa, it was reported Â that the method had often caused damages on the spermatozoaÂ membranes and resulted in decreasing of the spermatozoa quality. The damages of spermatozoa after SGDP Â processÂ were specifically caused by (I) the loss of seminalplasma, (II) the increase of free radicals, and (III) the collision or frictionÂ among the spermatozoa. Among the three causal factors above, the third or the physical factor is claimed to be the mostÂ important one. It was assumed that the first and the second factors can be overcome if the third one is avoided. TheÂ spermatozoa membranes consist of lipids, protein, carbohydrate, and some substances at a low rate. ThegeneralÂ objectives of this research was to identify the influence of the phospholipids PC (Phosphatidylcholin)to spermatozoa inÂ order to avoid the damages of the spermatozoa in the process of SGDP.
RESISTENSI OBAT MALARIA: MEKANISME DAN PERAN OBAT KOMBINASI OBAT ANTIMALARIA UNTUK MENCEGAH
Authors: Simamora Dorta , Fitri Loeki Enggar 
Published: January 2017

Multi drug resistance (MDR) of malariae parasite iscaused by decreasing ability of some antimalarial Â drugs examplesÂ chloroquine, mefloquine, antifolate and atovaquone Â to Plasmodium. Resistance to artemisin has not beenfound yet.Â Antimalaria drug resistance happened because some factors especially : genetic factor (gene mutation) Â of theÂ Plasmodium. Mechanism pathway of resistance differsin location, because the different target drug action. ResistanceÂ migh be reduce by using combination therapy.Â Key words: resistance, Plasmodium falciparum, antimalaria combination
PENGARUH PEMBERIAN PASTA TOMAT TERHADAP JUMLAH SEL BUSA PADA ARKUS AORTAAORTA ARCUS TUNICA INTIMA RATTUS NOVERGICUS STRAIN WISTAR TIKUS DENGAN YANG DIBERI DIET ATEROGENIK
Authors: Handayani Dian , Prijadi Bambang 
Published: January 2017

In Indonesia, the prevalence of coronary heart disease (CHD) was increased. It currently became the main cause ofÂ mortality. Unhealthy dietary pattern as the most determinant of atherosclerosis through the increasingof plasma LDL, willÂ be worsen by the presence of free radical such as reactive oxygen species (ROS) that led to accumulation ofÂ atherosclerosis plaques. The negative effects of free radicals can be inhibited by antioxidant. Lycopene is a strongÂ antioxidant that able to neutralize free radicals, Â especially oxygen derived free radicals. This studyaimed to assess theÂ effect of tomato paste containing lycopne to total Â foam cells. Lycopene has the role to prevent artericoronaria related toÂ atherosclerosis. The most lycopene source is tomatoproducts. This study was a laboratory-experimental study withÂ randomized control group â€“ post-test design. Twentyrandomly selected rats, divided into 5 Â treatment groups, group P1Â (normal diet treatment), P2 (atherogenic diet treatmen)t, P3 (atherogenic diet and addition 0.01 g/days oftomato pastaÂ treatment, P4 (atherogenic diet and addition 0.02 g/days of tomato pasta treatment,),
IDENTIIFKASI PROTEIN IMUNOGENIK CHLAMYDIA PNEUMONIAE TERHADAP SERUM PENDERITA INFARK MIOARD AKUT
Authors: Murwani Sri , Hidayati Dwi Yuni Nur 
Published: January 2017

Chlamydia pneumoniae is human respiratory tract pathogen and recently investigated as pathogen causingatherosclerosis and acute myocardial infarction (AMI). This research was carrier out to detect proteinpattern of C.Â pneumoniae, and to study it relation to AMI throughdetection of immunogenic protein. Design research Â was laboratoryÂ observational and analyzed descriptively. The subject was C. pneumoniae. Protein pattern the bacteria was detected byÂ electrophoresis method, and to detect the immunogenic protein was done immunoblotting. Serum was obtained from AMIÂ patients in Saiful Anwar and Lavallette hospitals. Â The result showed, protein pattern C. pneumoniae wasprotein withÂ molecular weight 117, 107, 97, 91, 86, 61, 58, 52, 46, 44, 34, 23, 19, 9, 5, 4 kDa. Immunogenic proteins vary betweenÂ AMI patients was 117, 107, 86, 61, 58, 52, 46, 44, Â 34 kDa. Non immunogenic proteins were 97, 91, 23, 19, 9, 5 and 4Â kDa. Protein 61 kDa react to all of patientâ€™s serum. It was concluded, C. pneumoniae have protein fractions 117, 107, 97,Â 91, 86, 61, 58, 52, 46, 44, 34, 23, 19, 9, 5, and 4kDa. Immunogenic proteins vary between AMI patients was 117, 107,Â 86, 61, 58, 52, 46, 44, 34 kDa, and 61 kDa was the Â immunodominant protein. The result proved C. pneumoniae asÂ causative agent of atherosclerosis and acute myocardial infarction, in Indonesia particularly.Â Key words:C. pneumoniae, immunogenic, AMI
PENGARUH STRESOR PSIKOLOGIK TERHADAP DISTRIBUSI TRANSPORTER SEROTONIN (SERT) DAN INDEKS APOPTOSIS HIPOKAMPUS YANG DIMEDIASI OLEH KORTISOL DAN IL â€“ 6
Authors: Suparno Suparno 
Published: January 2017

Generally, distress which followed by psychiatric disorders still become a medicinal practice controversial especiallyÂ psychologically stressor roles on holistic health condition. Therefore, research is needed to explain and clarify theÂ influences and the role of psychologically stressors on psychiatric disorders. This study used an psychoneuroimmunologicÂ paradigm, which used posttest-only true experiment Â design. About 24 female Rattus norvegicus strain Â Wistar had beenÂ used, divided into six groups. To investigate functional changes, we used hippocampus SERT distribution Â changes asÂ mirror of central serotonergic malfunction changes.The structural changes was measured by apoptosis index ofÂ hippocampus CA3 regions (hippocampus slicing). We also took the blood from the rats heart to examine Â IL â€“ 6 andÂ cortisol level.Â Psychological stressors lead to measuring of functional and structural changes include hippocampus SERT distributionÂ and increase hippocampus apoptotic index, that finally arise the distress.These results of statistical analyses demonstrateÂ that psychological stressors seem to be mediated by serotonergic neurotransmission pathway.Â Key words :hippocampus CA3 region, SERT malfunction, IL-6, cortisol, psychological stressors
FAKTOR YANG DIDUGA MENJADI RESIKO PADA ANAK DENGAN RINITIS ALERGI DI RSU DR. CIPTO MANGUNKUSUMO JAKARTA
Authors: Harsono Ganung , Munasir Zakiudin , Siregar Sjawitri P , Suyoko HEM Dadi , Kumiati Mia , Evalina Rita , Palupi Ratih D 
Published: January 2017

This researach was aimed to describe the risk factor profile of pediatric patients with allergic rhinitis. 1792 medical recordsof outpatients pediatric allergy immunology clinic in Cipto Mangunkusumo Hospital from 1997 to 2005. Fifty patients wereÂ diagnosed with allergic rhinitis and 22% of them Â were having allergic rhinitis with bronchial asthma.Allergic rhinitis wereÂ identified higher in boys (62%) than girls (38%) and ranged from 5 months to 13 years and 8 months old. Atopic historyÂ were identified in 24 patients (48) while atopic history in patient family were identified in mother (42%), father (40%), andÂ siblings (24%). Total IgE serum increased in 35 patients (88,57%) while total eosinophil serum increased in 28 patientsÂ (80%). The most common aeroallergen by skin prick test was house dust mite (36%) and the most common food allergenÂ was shrimp (40%). There were several factors that contribute to the development of allergic rhinitis such as age, sex,Â family atopic history and increasing in total IgE serum and total eosinophil serum . House dust mite and shrimp were theÂ most common allergen identified in allergic rhinitis.Â Keywords: allergic rhinitis, risk factors, pediatric
CYCLOOXYGENASE-2 (COX-2) EXPRESSION ON TESTIS CONNECTIVE TISSUE OF Rattus norvegicusAFTER TREATMENT WITH BETEL NUT EXTRACT (Areca catechu)
Authors: Akmal Muslim , Riawan Wibi 
Published: January 2017

Betel nut contains alcaloids such as arecoline, arecaine, arecaidine, arecolidine, guvacine, guvacoline and isoguvasine.Â Arecoline has ability to change gonad morph-function, including shape abnormality of sperm. This research was conductedÂ to prove the ability of betel nut extract (Areca catechu) in causing apoptosis on testis connective tissue of RattusÂ novergicus. This research used male; 2-3 months age, 150-200 grams body weight of white rats Rattus norvegicus strainÂ Wistar. The rats were divided into 5 groups in equalnumber, 3 rats respectively. They were a control group withoutÂ treatment and 4 groups as treatment groups which were given doses of betel nut extract, i,e., 1, 2, 3 Â and 4 gram duringÂ seven days. The result showed that dose variation ofbetel nut extract could induction of COX-2 expression on rats (RattusÂ norvegicus) strain Wistar testicular seminiferous tubule.Â Keywords: Betel nut extract, Rattus norvegicus, testis, cyclooxygenase-2
POTENSI Musca domesticaLinn. SEBAGAI VEKTOR BEBERAPA PENYAKIT
Authors: Hastutiek Poedji , Fitri Loeki Enggar 
Published: January 2017

Musca domestica is a fly which can be found aroundhouse and cage. Its present interference human hygiene, calmnessÂ and health. This fly generating many loss at human being and animal because this fly have high potency Â in spreadingÂ many diseases agents, that are protozoa, worm, virus, bacterium and fungi. Several agents of emerging,reemerging andÂ new emerging diseases can be transferred by M. domestica such as Cryptosporidium parvum, Helicobacter pylori,Â E.coli O157:H7 and H5N1. Agens removed by M. domestica through regurgitasi, excrete and exoskleleton. InterestinglyÂ M. domestica might be act as biological vector.Â Key words: Musca domestica, agent of disease
TGF-Î²MERUPAKAN MEDIATOR IMUNOSUPRESI DARI SEL T CD4 + CD25 + IN VITRO
Authors: Endharti Agustina Tri 
Published: January 2017

Naturally the existency of regulatory T cells are represented by CD4+CD25+T cells. Those cells have been identified as aÂ population of immuno-regulatory T cells, which mediated suppression of CD4+CD25+T cells by cellâ€“cell contact. In theÂ effectors phase the function of CD4+CD25+T regulatory T cells through the involvement of certain suppressive cytokines,Â such as TGF-Î². In this study, we demonstrated that CD4+CD25+Â cells produced high levels of Transforming GrowthÂ Factor-Î² (TGF-Î²) compared with CD4+CD25-T cells when stimulated by plate-bound anti-CD3 andsoluble anti-CD28. WeÂ observed that suppression ability of those cells could be abolished by the presence of antiâ€“TGF-Î². Finally, we found thatÂ stimulated CD4+CD25+T cells but not CD4+CD25-T cells express high and persistent levels of TGF-Î². This finding stronglyÂ suggests that CD4+CD25+T cells exert immuno-suppression by cellâ€“cell surfaces interaction involved cell of TGF-Î².Â Keyword: Sel T CD4+CD25+, TGF-Î², immunosupresion
PENGARUH PEMBERIAN KOMBINASI NAC DENGAN VITAMIN C DAN E TERHADAP STRES OKSIDATIF PADA HUVECs DIPAPAR PLASMA EKLAMPSIA
Authors: Baktiyani Siti Candra Windu 
Published: January 2017

The blood plasma of preeclampsia contains oxidative stress factors. The oxidative stress is predicted asthe cause of dis-function and destruction of endothelial cell which will influence the severity of Preeclampsia and Eclampsia complications.Â Previous research showed that the treatment of antioxidant on preeclamsia was still controvertion. The Â objectives of thisÂ research is to investigate the influence of the combination of NAC and vitamin C or vitamin E or bothof them on the levelÂ of H2O2, MDA, NO and GSH/GSSG ratio of endothelial cell culture exposed with Eclampsia plasma.The method wasanÂ experimental study using HUVECs exposed with to 2%plasma Eclampsia as an Eclampsia model invitro. TheHUVECsÂ were than treated with NAC 2ÂµM only (group 1), NAC2ÂµM + vitamin C 100 ÂµM (group 2) , NAC 2 ÂµM + vitamin E 100Â ÂµM (group 3), and NAC 2 ÂµM + vitamin C 100 ÂµM + vitamin E 100 ÂµM (group 4) for 24 hours. The parameter measuredÂ in this study were H2O2, MDA, NO and GSH/GSSG ratio. Result showed that H2O2, MDA, and NO concentration areÂ unsignificantly different among treatment groups although there was a decreasing on group treated with combination ofÂ NAC, vitamin C and Vitamin E.
LAPORAN KASUS: PERBANDINGAN PROSEDUR CUTLER BEARD DAN DIRECT CLORUSE PADA DEFEK PALPEBRA YANG LUAS AKIBAT TRAUMADI RSU DR. SAIFUL ANWAR MALANG
Authors: Kurniawan M. Iwan , Sadono Elfina G 
Published: January 2017

The paper aimed to report a different management ofreconstruction for large traumatic upper eyelid defect. Case 1 : aÂ 17 years old woman with traumatic upper eyelid defect in the right eye since 2 years old. The defect was linear but wide,Â looks like a triangle defect. Defect had repaired by direct closure. After the operation the defect remain. Case 2 : a 45Â years old man with more than 50 % traumatic upper eyelid defect in the left eye. Cutler-beard procedurwas made toÂ close the defect. Separation of the flap had been done at the second procedure. Cutler-beard procedure, done to theÂ second patient, had succed to close the upper eyelid defect. Reconstruction procedure carried out for Â the first patientÂ was not adequate to restore the large upper eyelid Â defect. Cutler-beard procedure is used for upper eyelid defectÂ involving more than 50% seem to have a good result.Key words: Cutler beard, Direct closure
PENGARUH PEMBERIAN MINYAK BUAH MERAH (Pandanus conoideus oil) TERHADAP PEMBENTUKAN FOAM CELLPADA AORTA TIKUS GALUR WISTAR (Rattus norvegicus) DENGAN DIET ATEROGENIK
Authors: Syarkiah Syarkiah , Fitri Loeki Enggar , Pudjirahaju Astutik 
Published: January 2017

Coronary heart disease serves as the main cause of death in the world. One of the effort to reduce therisk ofÂ coronary heart disease is by consuming food containing antioxidant. Red fruit contains high antioxidant,Â namely Î²-carotine (700 ppm) and alphatocopherol (500 ppm). This study was intended to find out the effect ofÂ red fruit oil (Pandanus conoideus oil) toward the formation of foam cell in wistar rat (Rattus norvegicus) withÂ atherogenic diet.This study was an experimental study, the design applied was complete randomized designÂ with 3 repetitions. The treatment in this study wasthe addition of red fruit oil in standard diet andatherogenicÂ one, comprising 8 groups, namely P0group (negative control), P1group (positive control), P2group (standardÂ diet + red Fruit Oil 0,12 ml/day), P3group (standard diet + red Fruit Oil 0,24 ml/day),P4group (standard diet +Â red Fruit Oil 0,36 ml/day), P5group (atherogenic diet + red Fruit Oil 0,12 ml/day), P6group (atherogenic diet +Â red Fruit Oil 0,24 ml/day), and P7group (atherogenic diet + red Fruit Oil 0,36 ml/day). The parameter was theÂ number of foam cells. The process and data analysisapplied Oneway Anova statistical test, followed withÂ DMRT (Duncan Multiple Range Test) statistical test.The result of Oneway Anova statistical test indicated thatÂ there was a significant difference of foam cell number among groups (p = 0,000). The conclusion inferredÂ from this study is that the addition of red fruit oil with dosage 0.24 ml/day and 0,36 ml/day may significantlyÂ obstruct the formation of foam cell in wistar strain rat with atherogenic diet.