bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between temperature and apparent shape of pristine ice crystals
derived from polarimetric cloud radar observations during the ACCEPT campaign
Authors: Myagkov Alexander , Seifert Patric , Wandinger Ulla , Bühl Johannes , Engelmann Ronny 
Published: August 2016

Abstract. This paper presents first quantitative estimations of apparent ice particle shape at the top of liquid-topped clouds. Analyzed ice particles were formed under mixed-phase conditions in the presence of supercooled water and in the temperature range from −20 to −3 °C. The estimation is based on polarizability ratios of ice particles measured by a Ka-band cloud radar MIRA-35 with hybrid polarimetric configuration. Polarizability ratio is a function of the geometrical axis ratio and the dielectric properties of the observed hydrometeors. For this study, 22 cases observed during the ACCEPT (Analysis of the Composition of Clouds with Extended Polarization Techniques) field campaign were used. Polarizability ratios retrieved for cloud layers with the cloud-top temperatures of  ∼ −5,  ∼ −8,  ∼ −15, and  ∼ −20 °C were 1.6, 0.9, 0.6, and 0.9, respectively. Such values correspond to prolate, quasi-isotropic, oblate, and quasi-isotropic particles, respectively. Data from a free-fall chamber were used for the comparison. A good agreement of detected apparent shapes with well-known shape–temperature dependencies observed in laboratories was found. Polarizability ratios used for the analysis were estimated for areas located close to the cloud top, where aggregation and riming processes do not strongly affect ice particles. We concluded that, in microwave scattering models, ice particles detected in these areas can be assumed to have pristine shapes. It was also found that even slight variations of ambient conditions at the cloud top with temperatures warmer than  ∼ −5 °C can lead to rapid changes of ice crystal shape.
Variations of deep soil moisture under different vegetation types and
influencing factors in a watershed of the Loess Plateau, China
Authors: Fang Xuening , Zhao Wenwu , Wang Lixin , Feng Qiang , Ding Jingyi , Liu Yuanxin , Zhang Xiao 
Published: August 2016

Abstract. Soil moisture in deep soil layers is a relatively stable water resource for vegetation growth in the semi-arid Loess Plateau of China. Characterizing the variations in deep soil moisture and its influencing factors at a moderate watershed scale is important to ensure the sustainability of vegetation restoration efforts. In this study, we focus on analyzing the variations and factors that influence the deep soil moisture (DSM) in 80–500 cm soil layers based on a soil moisture survey of the Ansai watershed in Yan'an in Shanxi Province. Our results can be divided into four main findings. (1) At the watershed scale, higher variations in the DSM occurred at 120–140 and 480–500 cm in the vertical direction. At the comparable depths, the variation in the DSM under native vegetation was much lower than that in human-managed vegetation and introduced vegetation. (2) The DSM in native vegetation and human-managed vegetation was significantly higher than that in introduced vegetation, and different degrees of soil desiccation occurred under all the introduced vegetation types. Caragana korshinskii and black locust caused the most serious desiccation. (3) Taking the DSM conditions of native vegetation as a reference, the DSM in this watershed could be divided into three layers: (i) a rainfall transpiration layer (80–220 cm); (ii) a transition layer (220–400 cm); and (iii) a stable layer (400–500 cm). (4) The factors influencing DSM at the watershed scale varied with vegetation types. The main local controls of the DSM variations were the soil particle composition and mean annual rainfall; human agricultural management measures can alter the soil bulk density, which contributes to higher DSM in farmland and apple orchards. The plant growth conditions, planting density, and litter water holding capacity of introduced vegetation showed significant relationships with the DSM. The results of this study are of practical significance for vegetation restoration strategies, especially for the choice of vegetation types, planting zones, and proper human management measures.
Geosphere coupling and hydrothermal anomalies before the 2009 Mw 6.3 L'Aquila earthquake in Italy
Authors: Wu Lixin , Zheng Shuo , De Santis Angelo , Qin Kai , Di Mauro Rosa , Liu Shanjun , Rainone Mario Luigi 
Published: August 2016

Abstract. The earthquake anomalies associated with the 6 April 2009 Mw 6.3 L'Aquila earthquake have been widely reported. Nevertheless, the reported anomalies have not been so far synergically analyzed to interpret or prove the potential lithosphere–coversphere–atmosphere coupling (LCAC) process. Previous studies on b value (a seismicity parameter from Gutenberg–Richter law) are also insufficient. In this work, the spatiotemporal evolution of several hydrothermal parameters related to the coversphere and atmosphere, including soil moisture, soil temperature, near-surface air temperature, and precipitable water, was comprehensively investigated. Air temperature and atmospheric aerosol were also statistically analyzed in time series with ground observations. An abnormal enhancement of aerosol occurred on 30 March 2009 and thus proved quasi-synchronous anomalies among the hydrothermal parameters from 29 to 31 March in particular places geo-related to tectonic thrusts and local topography. The three-dimensional (3-D) visualization analysis of b value revealed that regional stress accumulated to a high level, particularly in the L'Aquila basin and around regional large thrusts. Finally, the coupling effects of geospheres were discussed, and a conceptual LCAC mode was proposed to interpret the possible mechanisms of the multiple quasi-synchronous anomalies preceding the L'Aquila earthquake. Results indicate that CO2-rich fluids in deep crust might have played a significant role in the local LCAC process.
Soil CO2 efflux in an old-growth southern conifer forest (Agathis australis) – magnitude, components and controls
Authors: Schwendenmann Luitgard , Macinnis-Ng Cate 
Published: August 2016

Abstract. Total soil CO2 efflux and its component fluxes, autotrophic and heterotrophic respiration, were measured in a native forest in northern Aotearoa–New Zealand. The forest is dominated by Agathis australis (kauri) and is on an acidic, clay rich soil. Soil CO2 efflux, volumetric soil water content and soil temperature were measured bi-weekly to monthly at 72 sampling points over 18 months. Trenching and regression analysis was used to partition total soil CO2 efflux into heterotrophic and autotrophic respiration. The effect of tree structure was investigated by calculating an index of local contribution (Ic, based on tree size and distance to the measurement location) followed by correlation analysis between Ic and total soil CO2 efflux, root biomass, litterfall and soil characteristics. The measured mean total soil CO2 efflux was 3.47 µmol m−2 s−1. Autotrophic respiration accounted for 25 % (trenching) or 28 % (regression analysis) of total soil CO2 efflux. Using uni- and bivariate models showed that soil temperature was a poor predictor of the temporal variation in total soil CO2 efflux (<  20 %). In contrast, a stronger temperature sensitivity was found for heterotrophic respiration (around 47 %). We found significant positive relationships between kauri tree size (Ic) and total soil CO2 efflux, root biomass and mineral soil CN ratio within 5–6 m of the sampling points. Using multiple regression analysis revealed that 97 % of the spatial variability in total soil CO2 efflux in this kauri-dominated stand was explained by root biomass and soil temperature. Our findings suggest that biotic factors such as tree structure should be investigated in soil carbon related studies.
Characterization of Keratin Degrading Alkaliphiles
Authors: Elsayed Ashraf Abdelmotaleb , Mowafy Amr M. , Elrazak Ahmed Abd , Fawzy Mahmoud M. , Osman Yehia 
Published: August 2016

<p class="jbls-body"><span lang="EN-GB">Feather which mainly contains Keratin is one of the main poultry industry wastes and at the same time with high nutritional value if converted to soluble form. In this study, we isolated and characterized four alkaliphilic bacteria for their ability to degrade feather under alkaline conditions. Two of the isolates have been identified as <em>Lysinibacillus</em> spp. and both of them are growing optimally at 30 °C and pH 9. The others were identified as <em>Micrococcus</em> sp. and <em>Nocardiopsis</em> sp. and both of them showed optimum growth at 37 °C and pH 10.5. All the isolates are promising and potential tools that could be used for keratin degradation.</span></p>
Combined Tomography and Epithelial Thickness Mapping for Diagnosis of Keratoconus
Authors: Silverman Ronald H. , Urs Raksha , RoyChoudhury Arindam , Archer Timothy J. , Gobbe Marine , Reinstein Dan Z. 
Published: August 2016

Purpose Scanning Scheimpflug provides information regarding corneal thickness and 2-surface topography while arc-scanned high-frequency ultrasound allows depiction of the epithelial and stromal thickness distributions. Both techniques are useful in detection of keratoconus. Our aim was to develop and test a keratoconus classifier combining information from both methods. Methods We scanned 111 normal and 30 clinical keratoconus subjects with Artemis-1 and Pentacam data. After selecting one random eye per subject, we performed stepwise linear discriminant analysis on a dataset combining parameters generated by each method to obtain classification models based on each technique alone and in combination. Results Discriminant analysis resulted in a 4-variable model (R2 = 0.740) based on Artemis data alone and a 4-variable model (R2 = 0.734) using Pentacam data alone. The combined model (R2 = 0.828) consisted of 3 Artemis- and 4 Pentacam-derived variables. The combined model R value was significantly higher than either model alone (p = 0.031, one-tailed). In cross-validation, Artemis had 100% sensitivity and 99.2% specificity, Pentacam had 97.3% sensitivity and 98.0% specificity, and the combined model had 97.3% sensitivity and 100% specificity. Conclusions Pentacam, Artemis, and combined models were all effective in distinguishing normal from clinical keratoconus subjects. From the standpoint of variance explained by the model (R2 values), the combined model was most effective. Application of the model to early and subclinical keratoconus will ultimately be required to assess the effectiveness of the combined approach.
Effect of Metabolic Acidosis on QT Intervals in Patients with Chronic Kidney Disease
Authors: Yenigun Ezgi Coskun , Aypak Cenk , Turgut Didem , Aydin Mehmet Zafer , Dede Fatih 
Published: August 2016

Background There is a strong association between chronic kidney disease (CKD) and cardiovascular events. Increased arrhythmia risk in kidney disease is one of the main predominant factors in increased mortality and sudden cardiac death. To estimate this risk, noninvasive measurement of repolarization abnormalities including QT interval and its heart rate-corrected value (QTc) with surface ECG, are commonly used parameters in clinical practice. The aim of this study is to examine the effect of CKD-related problems – mainly acidosis – on QT intervals. Methods 30 patients with stage 3–5 CKD whose serum bicarbonate concentrations below 20 mmol/L were included in the study. Alkali therapy with oral sodium bicarbonate was used to maintain the serum bicarbonate concentration in the normal range. At the beginning all patients had sinus rhythm on surface ECG records. Kidney function tests including serum urea, serum creatinine, uric acid, blood gas analysis, and electrolytes were analyzed at the beginning and at the end of alkali treatment. All patients underwent 12 lead-ECGs, recorded simultaneously. One cardiologist examined the ECGs manually in terms of QT intervals, corrected for heart rate (QTc), QT dispersion (QTd) and corrected QT dispersion (QTcd). Results There were statistically significant differences in QT intervals, QTc, QTd and QTcd before and after sodium bicarbonate treatment. The correlation analyses revealed that there were significant negative correlations in pretreatment ECGs of patients between QTd and QTcd with blood pH level. Multivariate analyses between biochemical parameters and QTd-QTcd intervals have revealed that pH was related to QTd and QTc. Conclusions This study demonstrated that QT intervals on surface ECG are decreased after treatment of acidosis in CKD. Further studies are needed to show whether increased QT intervals cause ventricular arrhythmias in CKD.
Pre-Dialysis and Post-Dialysis Hydration Status and N-Terminal Pro-Brain Natriuretic Peptide and Survival in Haemodialysis Patients
Authors: Tangvoraphonkchai Kamonwan , Davenport Andrew 
Published: August 2016

Purpose Many dialysis centres have no formal program for assessing and adjusting post-haemodialysis (HD) target weight. Apart from clinical assessment, there are bioimpedance devices and natriuretic peptides that could potentially aid clinical management. We wished to determine whether pre- or post-HD bioimpedance assessment of extracellular water (ECW) or N terminal probrain natriuretic peptide (NT-proBNP) affected patient outcomes. Methods Multi-frequency bioimpedance assessments (MFBIA) were made before and after the midweek dialysis session, along with a post-dialysis NT-proBNP measurement. Results Data from 362 patients, median age of 63 (50–76) years, 59.7% male, 41.2% Caucasoid, with a median dialysis vintage of 31.4 (13.5–61.7) months were available for review. During a median follow-up of 49.6 (21.9–50.2) months there were 110 (30.4%) deaths. Patients who died had significantly increased ECW, as % over-hydrated both pre-HD 6.6 (5.8–7.6)% vs. survivors 5.1 (4–6.6)%, and post-HD 5.1 (4–6.6)% vs. 0.5 (-1-2.2.0, p<0.001, respectively. They also had higher NT-proBNP 325 (122–791) vs. 102 (48–342) pmol/l, p = 0.002. Using an adjusted Cox model, pre-HD ECW overhydration remained an independent factor associated with mortality (overhydration %: hazard ratio 1.15, 95% limits 1.03–1.28, p = 0.013), with a receiver operator curve (ROC) value of 0.7. Conclusions ECW excess is associated with increased mortality for HD patients, with ECW excess pre-dialysis being the strongest association, although these patients also had increased ECW post dialysis. Future trials are required to determine whether achieving euvolaemia as determined by bioimpedance improves patient survival.
Evidence-Based Criteria for the Choice and the Clinical use of the Most Appropriate Lock Solutions for Central Venous Catheters (Excluding Dialysis Catheters): A GAVeCeLT Consensus
Authors: Pittiruti Mauro , Bertoglio Sergio , Scoppettuolo Giancarlo , Biffi Roberto , Lamperti Massimo , Dal Molin Alberto , Panocchia Nicola , Petrosillo Nicola , Venditti Mario , Rigo Carla , DeLutio Enrico 
Published: August 2016

Background The most appropriate lock solution for central venous access devices is still to be defined. GAVeCeLT – the Italian group for venous access devices – has developed a consensus on the evidence-based criteria for the choice and the clinical use of the most appropriate lock solution for central venous catheters (excluding dialysis catheters). Method After the constitution of a panel of experts, a systematic collection and review of the literature has been performed, focusing on clinical studies dealing with lock solutions used for prevention of occlusion (heparin, citrate, urokinase, recombinant tissue plasminogen activator [r-TPA], normal saline) or for prevention of infection (citrate, ethanol, taurolidine, ethylene-diamine-tetra-acetic acid [EDTA], vancomycin, linezolid and other antibiotics), in both adults and in pediatric patients. Studies on central lines used for dialysis or pheresis, on peripheral venous lines and on arterial lines were excluded from this analysis. Studies on lock solutions used for treatment of obstruction or infection were not considered. The consensus has been carried out according to the Delphi method. Results The panel has concluded that: (a) there is no evidence supporting the heparin lock; (b) the prevention of occlusion is based on the proper flushing and locking technique with normal saline; (c) the most appropriate lock solution for infection prevention should include citrate and/or taurolidine, which have both anti-bacterial and anti-biofilm activity, with negligible undesired effects if compared to antibiotics; (d) the patient populations most likely to benefit from citrate/taurolidine lock are yet to be defined. Conclusions The actual value of heparinization for non-dialysis catheters should be reconsidered. Also, the use of lock with substances with anti-bacterial and anti-biofilm activity (such as citrate or taurolidine) should be taken into consideration in selected populations of patients.
Rating Scale for the Assessment of Competence in Ultrasound-guided Peripheral Vascular Access – a Delphi Consensus Study
Authors: Primdahl Stine C. , Todsen Tobias , Clemmesen Louise , Knudsen Lars , Weile Jesper 
Published: August 2016

Introduction Peripheral vascular access is vital for treatment and diagnostics of hospitalized patients. Ultrasound-guided vascular access (UGVA) is superior to the landmark technique. To ensure competence-based education, an assessment tool of UGVA competence is needed. We aimed to develop a global rating scale (RS) for assessment of UGVA competence based on opinions on the content from ultrasound experts in a modified Delphi consensus study. Methods We included experts from anesthesiology, emergency medicine and radiology across university hospitals in Denmark. Nine elements were drafted based on existing literature and recommendations from international societies. In a multi-round survey, the experts rated the elements on a five-point Likert scale according to importance, and suggested missing elements. The final Delphi round occurred when >80% of the experts rated all elements ≥4 on the Likert scale. Results Sixteen experts consented to participate in the study, one withdrew consent prior to the first Delphi round, and 14 completed all three Delphi rounds. In the first Delphi round the experts excluded one element from the scale and changed the content of two elements. In the second Delphi round, the experts excluded one element from the scale. In the third Delphi round, consensus was obtained on the eight elements: preparation of utensils, ergonomics, preparation of the ultrasound device, identification of blood vessels, anatomy, hygiene, coordination of the needle, and completion of the procedure. Conclusions We developed an RS for assessment of UGVA competence based on opinions of ultrasound experts through a modified Delphi consensus study.
Echo Color Doppler Ultrasound: A Valuable Diagnostic Tool in the Assessment of Arteriovenous Fistula in Hemodialysis Patients
Authors: Mudoni Anna , Caccetta Francesco , Caroppo Maurizio , Musio Fernando , Accogli Antonella , Zacheo Maria Dolores , Burzo Maria Domenica , Gallieni Maurizio , Nuzzo Vitale 
Published: August 2016

A functioning vascular access is a critical requirement to improve the quality of life in hemodialysis patients, so monitoring and surveillance of vascular access play key roles in identifying all dysfunctions and reducing the huge economic cost as well as adequacy of dialysis. In our five-year experience, a study protocol has been used and improved with the help of ultrasonography. Doppler ultrasound is an excellent and sensitive modality for hemodialysis access evaluation, one of techniques employed for arteriovenous fistulae (AVF) study, not only as a pre-operative tool, but also in post-operative monitoring of AVF maturation. In addition, the current guidelines recommend AVF surveillance by access blood flow measurement and the correction of hemodynamic stenosis in order to prolong access survival. Doppler ultrasound is readily available, directly used by nephrologists, non-invasive, safe, inexpensive, reproducible, although it requires more clinical skill and time to perform and proper equipment. Ultrasonography imaging can substantially reduce the number of subsequent invasive angiographic procedures. In our opinion, Doppler ultrasound should have a crucial place in the interdisciplinary cooperation in AVF monitoring and it should be included as part of an integrated vascular access management program.
Combined Modality Therapy for Thoracic and head and Neck Cancers: A Review of Updated Literature Based on a Consensus Meeting
Authors: Franco Pierfrancesco , Fiorentino Alba , Dionisi Francesco , Fiore Michele , Chiesa Silvia , Vagge Stefano , Cellini Francesco , Caravatta Luciana , Tombolini Mario , De Rose Fiorenza , Meattini Icro , Mortellaro Gianluca , Apicella Giuseppina , Marino Lorenza , Greto Daniela 
Published: August 2016

Purpose Combined modality therapy is a mainstay option for thoracic malignancies and head and neck cancers. The integration of different strategies is based on the multidisciplinary approach of modern clinical oncology. Radiation oncologists have to be educated, trained, and updated to provide state-of-the-art care to cancer patients and thus educational meetings are crucial. Methods The Italian Association of Radiation Oncology Young Members Working Group (AIRO Giovani) organized its 8th national meeting, focused on combination therapy in lung, esophageal, and head and neck cancer (with a specific focus on larynx-preservation strategies for larynx/hypopharynx tumors), involving young professionals working in Italy. The meeting was addressed to young radiation oncologists, presenting state-of-the-art knowledge, based on the latest evidence in this field. We performed a review of the current literature based on the highlights of the Congress. Results The multimodality approach of head and neck and thoracic malignancies includes surgery, chemotherapy, and radiotherapy, but also has to take into account new information and data coming from basic and translational research and including molecular biology, genetics, and immunology. All these aspects are crucial for the treatment of non-small-cell lung cancer and esophageal, esophagogastric junction, and larynx/hypopharynx malignancies. The integration of different treatments in the clinical decision-making process to combine therapies is crucial. Conclusions Combination therapy has proved to be a consolidated approach in these specific oncologic settings, highlighting the importance of multimodality management in modern clinical oncology. Dedicated meetings on specific topics are helpful to improve knowledge and skills of young professionals in radiation oncology.