bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multidrug-resistant tuberculosis of spine diagnosis and management: An institutional experience of 21 cases
Authors: Bhosale Sunil , Ariwala Dipen Mukesh , Phupate Akshay , Marathe Nandan , Seshadri Harini , Sheth Umang 
Published: September 2024

Background:
We aimed to establish a standardized protocol for managing multidrug-resistant (MDR) spinal tuberculosis (TB), addressing the surgical options, ranging from computed tomography-guided biopsy to intraoperative sampling.

Methods:
This study developed a treatment/management protocol based on an analysis of clinical, radiological, and postoperative outcomes for 21 patients with spinal MDR-TB. Over 24 months, 21 patients with multidrug-resistant spinal TB underwent the following testing: erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), numerical rating scale (NRS), and the American Spinal Injury Association Scale. Radiological criteria were based upon a comparison of preoperative and 6-month to 2-year postoperative plain radiographs.

Results:
The 21 patients underwent guided biopsies (35%) or intraoperative sampling (65%). For the surgical cases, dorsal vertebrae were most frequently involved (75%), and 90% underwent posterior surgical procedures. Postoperatively, ESR, CRP, kyphosis angle, and NRS score were significantly reduced. The 3 MDR patients who failed treatment were transitioned to the extensively drug-resistant (XDR) protocol wherein bedaquiline, linezolid, cycloserine, and clofazimine were given after drug sensitivity testing drug regimen, needed no further surgery, and none exhibited additional neurological deterioration.

Conclusion:
Regular clinical, laboratory, radiological, and outcome analysis is vital for following MDR spinal TB patients; early detection of relatively rare treatment failures (i.e., 3/21 patients in this series) allows for prompt initiation of XDR treatment, resulting in better outcomes.
Value-based healthcare in management of chronic back pain: A multidisciplinary- and lean-based approach
Authors: Montemurro Nicola , Zotti Nunzio , Guercini Jacopo , De Carolis Giuliano , Leoni Chiara , Marotta Roberto , Tomei Renata , Baggiani Angelo , Paolicchi Adriana , Lazzini Simone , Di Serafino Francesca 
Published: September 2024

Background:
Chronic back pain stands as the most common musculoskeletal disorder and a primary cause of disability in people under 45 years old. Multidisciplinary consultation offers an efficient approach to chronic back pain management compared to traditional therapeutic-rehabilitative paths. This paper aims to show the benefit of a diagnostic-therapeutic multidisciplinary program pathway for patients with chronic back pain.

Methods:
Twenty-six patients who underwent a second-level multidisciplinary consultation with a neurosurgeon and a pain therapist at our University Hospital were retrospectively identified from April 2023 to September 2023. The second-level multidisciplinary consultation is a second step consultation after a first consultation with a single specialist doctor (neurosurgeon, orthopedic, and pain therapist) who did not get the diagnosis and/or did not solve the painful symptom after medical or surgical treatment. Clinical outcomes, patient experience, and cost-effectiveness analysis were assessed using lean healthcare tools.

Results:
With the introduction of second-level multidisciplinary consultation, patients were assessed by multiple physicians during a single visit, reducing the costs of individual visits, reducing the time to obtain the diagnosis, and facilitating early agreement on a diagnostic-therapeutic plan. The lean value-based healthcare approach showed an average of 45 working days lost per single patient and a total cost per single patient with chronic back pain of € 1069 for the national health system for an average Lead time of 18 months. Questionnaire analysis on service quality and utility, along with overall satisfaction, revealed excellent resolution of back pain in 53.8% of cases and partial resolution of back pain in 11.5% of cases after second-level multidisciplinary consultation.

Conclusion:
Our multidisciplinary approach to chronic back pain has significantly improved healthcare efficiency. This new proposed clinical model reduces waiting times and costs and improves patient experience by improving clinical outcomes in the management of chronic back pain.
The use of ultrasound-guided imaging to localize peripheral nerve injury in pediatric patients: A case report
Authors: Sowah Mareshah N. , Klein Benjamin R. , Attiah Mark , Pereda Nidia I. Perez , Murray Roseanna A. , John Danny Lincoln , Panday Avidesh , Levi Allan D. 
Published: September 2024

Background:
The use of ultrasonography to diagnose and manage peripheral nerve injury is not routinely performed, but is an advantageous alternative to magnetic resonance imaging (MRI) in the pediatric population.

Case Description:
The authors report a case of a toddler-aged female who sustained a supracondylar fracture and subsequent median and ulnar nerve injuries. All preoperative and postoperative imaging was performed through high-resolution ultrasound as opposed to MRI. Starting at 6 months post-nerve repair and with 18 months of follow-up, the patient exhibited substantial improvement in motor strength and sensory function. This case demonstrated a successful outcome while providing an imaging alternative that is portable, relatively low-cost, lacks ionizing radiation, provides additional information on vascular integrity, and obviates the need for general anesthetic such as MRI.

Conclusion:
The authors conclude that the use of ultrasonography to diagnose and manage traumatic peripheral nerve injury is advantageous, particularly in the pediatric population.
Оverview of materials of the All-Russian Scientific Conference with international participation “Russian Student Christian Movement: pages of history and experience of ‘making life ecclesial’ (otserkovlenie)” (Moscow, October 4–5, 2023)
Authors: Скоробогатова И.Ю. 
Published: September 2024

4–5 октября 2023 г. в Москве состоялась конференция, приуроченная к 100-летнему юбилею Русского студенческого христианского движения (далее — РСХД). Организаторами конференции выступили Свято-Филаретовский институт и Дом русского зарубежья им. А. И. Солженицына. РСХД стало одним из наиболее ярких и значимых явлений русской эмиграции и Православной церкви последнего столетия. Движение возникло в среде эмигрантов из России как объединение христианских студенческих кружков, стремившихся к оцерковлению жизни.
On October 4–5, 2023, a conference dedicated to the 100th anniversary of the Russian Student Christian Movement (hereinafter referred to as RSCM) was held in Moscow. The conference was organized by the St. Philaret Institute and the A. I. Solzhenitsyn House of Russians Abroad. RSCM has become one of the most striking and significant phenomena of the Russian emigration and the Orthodox Church of the last century. The movement arose among emigrants from Russia as an association of Christian student circles striving to bring life into the Church.
The Parables of Jesus Christ in the “Ladder” of John of Sinai (based on the Russian Translation of Optina Pustyn)
Authors: Попова Т.Г. 
Published: September 2024

В статье рассматриваются евангельские притчи, вошедшие в текст Лествицы Иоанна Синайского, которые являются важнейшими символическими ключами, позволяющими понять смысл фрагментов книги. Всего в тексте Лествицы выявлено 148 явных и скрытых отсылок к евангельским притчам. Наиболее часто в памятнике встречаются притчи о добром пастыре и о сеятеле. Важнейшим смысловым блоком, на котором строится образность Лествицы, являются притчи эсхатологического характера: о верном слуге, о брачном пире, о десяти девах, о неплодной смоковнице и винограднике. Особое значение в структуре и семантике текста Лествицы имеет притча о сокровище, скрытом на поле: под этим сокровищем понимаются христианские добродетели, главной из которых является смиренномудрие. Особые способы и приемы введения евангельского текста в текст Лествицы не обнаружены: фрагменты из Священного писания настолько искусно вплетаются в ткань повествования, что обнаружение их является сложной филологической задачей. Истоки смысловой глубины и образности Лествицы как литературного памятника кроются в его библейском контексте. В статье анализируются 14 из 22 евангельских притч Иисуса Христа. Материалом для анализа явился текст русского перевода Лествицы, выполненный в Оптиной пустыни, впервые опубликованный в 1862 г. В статье указываются примеры употребления названных притч в тексте Лествицы.
The article examines the Gospel parables included in the text of the Ladder by John of Sinai which are the most important symbolic clues to understand the meaning of the book’s fragments. In total, 148 explicit and hidden references to the Gospel parables were revealed in the text of the Ladder. The most frequently occurring parables in the monument are the parables of the good shepherd and the sower. The most important semantic block, on which the imagery of the Ladder is based, is the parables of eschatological character: the parables of the faithful servant, the wedding feast, the ten virgins, the unfruitful fig tree and the vineyard. Of particular importance in the structure and semantics of the text of the Ladder is the parable of the treasure hidden in the field: this treasure refers to the Christian virtues, the main of which is humility. We have not found special ways and techniques of introducing the Gospel text into the text of the Ladder: fragments from the Holy Scriptures are so artfully woven into the fabric of the narrative that discovering them is a challenging philological task. The origins of the semantic depth and imagery of the Ladder as a literary monument lie in its biblical context. The article analyses 14 of the 22 Gospel parables of Jesus Christ. The material for the analysis was the text of the Russian translation of the Ladder, made in the Optina Pustyn, first published in 1862. The article provides examples of the use of these parables in the text of the Ladder.
Book review: Odintsov M. I., Kochetova A. S. Freedom of Conscience in the History of Russia: Ideas, Legislative Projects, Practical implementation. The end of the 19th — the first quarter of the 20th century Moscow : Political Encyclopedia, 2023. 553 p.
Authors: Шилкина М.В. 
Published: September 2024

Свобода совести есть важнейший элемент и условие свободы человека от любой формы угнетения. Становление правового государства в России, решение многих региональных и национальных проблем, в которых значительную роль играет религия, делают эту проблему крайне актуальной для России. Поэтому появление каждой новой книги, посвященной анализу вопросов свободы совести, представляется важным и своевременным.
Freedom of conscience is the most important element and condition of human freedom from any form of oppression. The formation of a legal state in Russia, the solution of many regional and national problems, in which religion plays a significant role, make this problem extremely relevant for Russia. Therefore, the appearance of each new book devoted to the analysis of issues of freedom of conscience seems important and timely.
Religious philosophers of Russian emigration in search of a social Christian alternative to the socialist and capitalist structure of society
Authors: Буров А.А. 
Published: September 2024

Видное место в идейной жизни русской эмиграции в период между двумя мировыми войнами занимали представители «веховского» направления русской религиозной философии и близкие к ним «новоградцы». Важным направлением их духовных и интеллектуальных усилий было стремление найти и выразить наиболее адекватное социальное воплощение христианства, свободное от недостатков как капитализма, так и социализма — так называемое социальное христианство. Под этим углом зрения они рассматривали социальное учение Католической церкви и корпоративный строй. В настоящее время существуют серьезные исследования различных сторон деятельности и идейного наследия мыслителей «веховской традиции». Однако до сих пор нет специального исследования социальных смыслов христианства, выявленных в их трудах. Цель настоящей статьи — помочь восполнению этого пробела и показать, как эти мыслители внутри соответствующего исторического контекста в межвоенный период (с 1922 по 1940 г.) и в соотнесении со взглядами своих западных коллег понимали социальные смыслы христианства, а также как они видели их наиболее оптимальное воплощение в жизни общества. Речь пойдет о текстах собственно «веховцев» (авторов «Вех») С. Л. Франка, прот. Сергия Булгакова, Н. А. Бердяева и близкого к ним П. И. Новгородцева и о текстах их ближайших последователей и преемников, представителей более молодого поколения — «новоградцев»: Г. П. Федотова, Ф. А. Степуна и И. И. Фондаминского.
Representatives of the “Vekhi” direction of Russian religious philosophy (Fr. Sergius Bulgakov, N. A. Berdyaev, S. L. Frank, P. I. Novgorodtsev) and “Novograd residents” close to them (G. P. Fedotov, F. A. Stepun, I. I Fondaminsky) occupy a prominent place in the ideological life of Russian emigration in the period between the two world wars. An important direction of their spiritual and intellectual efforts was the desire to find and express the most adequate social embodiment of Christianity, free from both the shortcomings of capitalism and socialism — the so-called “social Christianity”. From this angle they viewed the Social Teaching of the Catholic Church and the corporate system. Currently, there are serious studies of various aspects of the activities and ideological heritage of thinkers of the “Vekhi tradition”. However, there is still no special study of the social meanings of Christianity in their works. The purpose of this article is to begin to fill this gap and show how these thinkers, within the corresponding historical context in the interwar period (from 1922 to 1940) and in correlation with the views of their Western colleagues, understood the social meanings of Christianity, and how they saw their most optimal implementation in the life of society.
ENHANCING PERFORMANCE OF MANGO FARMING PROJECTS THROUGH PARTICIPATORY PROJECT MANAGMENT
Authors: Kisumbi Charles Kyale , Mulwa Angeline Sabina , Mbugua John Mwaura , Kikwatha Reuben Wambua 
Published: September 2024

Objective: This paper advocates for a paradigm shift from the traditional project management to a participatory approach throughout the management cycle, for increased performance of mango farming projects.

Theoretical Framework: Theories adopted: i. Project Management Theory: Highlights life cycle stages in uncovering new project insights. ii. Stakeholder Theory: Highlights the unity of stakeholders for enhanced involvement in projects. iii. Participation Ladder Theory: Enhances success through active participation. iv. Theory of Constraints: Confronts project challenges related to time, cost, and scope to achieve beneficial changes.

Method: The empirical study was carried out in Makueni County, Kenya. It used descriptive cross-sectional design and multistage rsampling on a population of 12,622, out of which a sample of 375 respondnets selected. Of these, 369 questionnaires were returned and analyzed. Additionally, it involved 15 key informants. Observation and an interview guides collected qualitative data. Descriptive and inferential tools, correlation, F-tests, regression and content analysis analyzed quantitative and qualitative data.

Results and Discussion: Results reflected item scores showing the composite mean of 3.2 and standard deviation of 3.0. Revealed is a significant positive correlation coefficient (r = 0.592), p-value (p = 0.000) of the relationship between two variables.

Research Implications: This study recommends adopting a participatory project cycle approach, supported by a feasible policy, to guide innovative mango farming practices to enhance the overall performance.

Originality/Value: The study contributes to literature by advocating project management cycle approach on performance of mango projects in today’s evolving project environment.
Bakhtin's Viva - Transcript - Edited by Professor John Shotter
Authors: Shotter John 
Published: September 2024

The Viva / Defense of Mikhail Bakhtin was performed at the Bedfordshire International Systemic Winter School February 2015. This transcript is an edited version of Comrade Bakhtin’s defence of his doctoral dissertation: "Rabelais in the History of Realism" at the Gorky Institute of World Literature in Moscow on 15 November 1946. Professor John Shotter edited the rather long transcript of the viva for this performance in February 2015 at Brathay Hall , Ambleside. The original translation was adapted and directed by Lars Kleberg and translated by Denis Zhernokleyev and Caryl Emerson for a round table reading at the 15th International Bakhtin Conference, Stockholm on 25 July 2014. The cast was made up of John Shotter and doctoral candidates on the Professional Doctorate in Systemic Practice. The video of the performance is here
Respon Pemberian Pupuk Daun Dan Pupuk Kandang Terhadap Pertumbuhan Bibit Kakao (Theobroma Cacao L.)
Authors: Yusuf Muhamad 
Published: September 2024

Penelitian ini bertujuan untuk mengetahui respon pertumbuhan bibit kakao terhadap pemberian pupuk daun dan pupuk kandang yang dilaksanakan pada bulan Januari – Maret 2016. Penelitian ini menggunakan Rancangan Acak Kelompok faktorial dengan 2 faktor perlakuan dan 3 ulangan. Faktor pertama adalah aplikasi pupuk daun terdiri atas D0 (0 Kg/ha), D1 (1 g/lt air),D2 (2 g/lt air). Faktor kedua adalah pupuk kandang terdiri dari K0 (0 Kg/polibag), K1 (1Kg/polibag) dan K2 (2 kg/polibag). Hasil penelitian menunjukkan bahwa aplikasi pupuk daun berpengaruh sangat nyata terhadap tinggi, diameter batang dan luas daun bibit kakao. Sedangkan aplikasi pupuk kandang berpengaruh nyata terhadap tinggi bibit dan tidak berbeda nyata terhadap luas daun,jumlah daun dan diameter batang.Kata Kunci : Pupuk daun, pupuk kandang, kakao
Pengaruh Berbagai Sumber Kalium Dan Pupuk Organik Cair Darah Sapi Terhadap Kualitas Jagung Manis (Zea mays saccharata Sturt.)
Authors: Paskalis Vincencius Duta , Astiningrum Murti , Anindyawati Nurul 
Published: September 2024

Penelitian ini bertujuan untuk menganalisis pengaruh pemberian jenis pupuk kalium dan POC darah sapi terhadap kualitas jagung manis varietas Master Sweet. Penelitian ini dilaksanakan pada bulan Februari -Mei 2023 di Desa Sidorejo, Kecamatan Bandongan, Kabupaten Magelang. Penelitian menggunakan percobaan faktorial (5x2) yang disusun dalam Rancangan Acak Kelompok Lengkap dua faktor, yaitu jenis pupuk kalium terdiri dari KCl, ZK, KNO3, MKP dan pemberian POC darah sapi. Data dianalisis menggunakan sidik ragam (ANOVA), diuji lanjut menggunakan uji beda nyata terkecil pada taraf 5 % dan 1 %. Hasil penelitian menunjukkan bahwa perlakuan menggunakan pupuk kalium KCl meningkatkan parameter panjang tongkol, berat segar dan kadar gula biji jagung manis. Pemberian POC darah sapi 400 ml/petak meningkatkan berat segar tanaman. Terjadi interaksi antara jenis pupuk kalium dan pemberian POC darah sapi pada parameter panjang tongkol, berat segar, kadar gula biji.
Estarão a Disfunção Sexual Feminina e a Contraceção Hormonal Interligadas?
Authors: Miranda Rafaela , Catarina Silva Ana , De Azevedo Patrícia , Gomes Ariana 
Published: September 2024

O efeito da contraceção hormonal (CH) na sexualidade feminina há muito que tem vindo a ser matéria de discussão. Alguns estudos sugerem que as experiências negativas relativamente ao uso de CH são as principais causas de descontinuação ou alteração do método contracetivo. Neste sentido, o principal objetivo do presente artigo será rever a literatura publicada sobre o tema nos últimos 10 anos e compreender a eventual relação entre o uso de contraceção e a disfunção sexual feminina.Foi realizada pesquisa da literatura, entre o dia 4 e 8 de Abril de 2022, nas principais bases de dados de medicina baseada na evidência, com data de publicação: janeiro de 2012 a março de 2022, utilizando os termos MeSH: feminine sexual dysfunction, oral contraceptives, e hormonal contraceptives. Foi consultado o Consenso sobre Contraceção (2020), o Protocolo de Ginecologia no âmbito dos Cuidados de Saúde Primários (2019) e o Diagnostic and Statistical Manual of Mental Disorders (DSM -V 2013).Os métodos contracetivos poderão apresentar efeitos negativos sobre a sexualidade feminina, nomeadamente na diminuição do desejo sexual e líbido. Dentro da CH é difícil retirar conclusões sobre qual o melhor método anticoncecional, no entanto, há vários estudos que sustentam que os dispositivos intrauterinos apresentam menor impacto na sexualidade feminina.Apesar da difícil avaliação da DSF e da disparidade de definições existentes, este é um problema real e que pode afetar significativamente a qualidade de vida das mulheres e do casal, e, para o qual, todos os médicos devem estar sensibilizados. É importante que haja um aconselhamento adequado e ajustado às expectativas de cada mulher, de forma a aumentar a adesão ao método e a satisfação da utilizadora.
Deleção Parcial do Gene CUL4B: Relato de Caso
Authors: Carvalho Oliveira Marques João Mário , Pereira Pinto Gisela 
Published: September 2024

As perturbações do desenvolvimento intelectual acarretam grande morbilidade e comportam um exigente desafio nas dimensões do indivíduo, da família e da comunidade. O CUL4B é um gene envolvido em diversos processos celulares e no controlo do ciclo celular. Mutações neste gene associam-se a alterações como deficiência intelectual, macrocefalia e dismorfias, entre outras.O caso reportado é referente a uma menina de 12 anos, com identificação precoce de dismorfias (face alongada com estreitamento bitemporal e fronte longa, olhos profundos, boca grande, pavilhões auriculares com implantação baixa e endentações no lóbulo da orelha, nariz com ponta de aspeto adunco) e de atrasos no desenvolvimento intelectual e psicomotor, tendo-se identificado, após estudo genético, uma doença rara associada ao cromossoma X (deleção em Xq24 envolvendo parcialmente o gene CUL4B). Dada a sua associação ao cromossoma X, esta patologia é rara no sexo feminino e a sua abordagem requer uma equipa multidisciplinar e uma articulação eficiente entre os serviços de saúde. Analisando este caso, podemos inferir sobre a importância da Medicina Geral e Familiar, atendendo às suas características e competências, na gestão do mesmo.