bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE DERIVATIVE WORDS FROM THE NOUNS WITH PREFIX НЕДО- (NEDO-) AS AN ACTIVE MODERN TREND DEVELOPMENT OF THE UKRAINIAN LANGUAGE IN DERIVATION
Authors: Khrustyk Nadiya M. 
Published: October 2024

The article is devoted to the study of active processes of word formation in the modern Ukrainian language. Its purpose is to study the activation of the production of noun derivatives formed by the prefix nedo-, as one of the regularities of the development of the modern process of word formation in the Ukrainian language. The object of research is the modern process of word formation in the Ukrainian language. The subject of the analysis is the increase in productivity of the substantive noun word-formation type with the prefix nedo- as a sign of the derivational process. The material of observation is substantive nouns formed by the prefix nedo-, which are characterized by negative semantics to indicate the inferiority of someone or something. As a result of the conducted research, the specifics of the derivation of substantive nouns formed by the prefix nedo- have been clarified. Conclusions. The reasons for the increase in the productivity of the word-formation type, on the basis of which the analyzed occasionalisms are created, are determined. Among them there are the political and socio-economic changes of the period of independent Ukraine, the events of the Russian-Ukrainian war, which require the nomination and assessment of new concepts; democratization of society; activation of specific word formation processes; high system performance of the studied word-formation type.
THE BOOK COVER AS A NON-VERBAL MEANS OF NARRATIVE CREATING (BASED ON J. K. ROWLING’S “HARRY POTTER AND THE GOBLET OF FIRE”)
Authors: Kosiuha Oleksandra O. 
Published: October 2024

This scientific research is devoted to the analysis of book covers of the fourth part of septology about the little sorcerer by the British author J. K. Rowling "Harry Potter and the Goblet of Fire". The purpose of the study is to identify the patterns of creation of illustrative images (on the cover) depending on the language of the work of fantasy literature and the target readership. The sample consists of publications in English (in the UK and the United States of America) and in Ukrainian. Particular attention was paid to the methods of creating covers by illustrators, their vision of the work and the target readership to which the publication was directed. The object of the study is a series of covers of the Harry Potter narrative in the English-speaking and Ukrainian-speaking society. The subject of the research is the process of influence of the book cover on the popularity of its narrative among readers in different countries and among different age groups. The issue of differences in the depiction of the novel by English-speaking illustrators in the original language (Bloomsbury Publishing House) and in American translation (Scholastic Publishing House), as well as by Ukrainian artists in the Ukrainian edition (A-BA-BA-HA-LA-MA-HA Publishing House) is considered. The results of the study are, on the one hand, the confirmation of the hypothesis regarding the dependence of the creation of illustrations by artists according to the language and the reader; on the other hand, it is found that the worldview of the illustrator himself is the basis for the depiction of the main characters on the cover of the novel.
Evaluación de la propiocepción en población estudiantil mediante el test de Romberg modificado: efecto de una intervención
Authors: Hernandez Arango Nicolas , Godoy Infante María Paula , González Briceño Sofía , Vásquez Martínez Diego Armando , Pérez Pérez Lisbet Yuliana , Chacón Durán Rafael Ricardo 
Published: October 2024

Antecedentes: La prueba de Romberg modificada es útil en la medición de la propiocepción de los adultos aún con su limitada aplicación en la actualidad por falta de consenso y uniformidad entre las diferentes pruebas. Sin embargo, esta es una prueba rápida, fiable, reproducible y económica. Objetivo: evaluar mediante la prueba de Romberg modificada, el impacto sobre la propiocepción cuando se implementa un programa de ejercicios de entrenamiento, en población universitaria. Materiales y Métodos: Estudio observacional, cuasiexperimental, de intervención antes-después, sin grupo control. Muestra de 53 estudiantes de medicina de la UPTC - Tunja en el periodo 2022-2.Se realizó una intervención de entrenamiento para estimular la propiocepción, cuyo impacto se evaluó mediante el test de Romberg modificado antes y después del entrenamiento. La información se tabuló y analizó en el software Epi-Info7, con técnicas de estadística descriptiva para las variables cuantitativas y para las variables categóricas se diseñaron tablas de contingencia. Resultados: se encontró un aumento del promedio del resultado final respecto al inicial para ambas lateralidades y en el mismo sentido se encontró una diferencia positiva, entre el resultado promedio final y el inicial, con un promedio inicial para la pierna derecha de 17 segundos y final de 21,6 segundos; para la pierna izquierda fueron de 16,6 segundos inicialmente y 21,4 segundos al final. La diferencia promedio de la pierna derecha fue de 5,09 segundos, siendo esta mayor que la diferencia de 4,75 segundos de la pierna izquierda. Conclusión: La prueba de Romberg modificada es útil en la medición de la propiocepción; El punto de corte de esta prueba es de 20 segundos, los resultados inferiores a este se considera un déficit propioceptivo y superiores indican el estado propioceptivo; La propiocepción es un sentido poco estudiado, ejercitado y evaluado que necesita más investigación y aplicación en la clínica, para prevenir lesiones.
Financial development, environmental regulation, and pollution emission: evidence from China
Authors: Pernet Thomas , Ruili Zhao 
Published: October 2024

Abstract

This study investigates the relationship between financial development and pollution emissions in Chinese cities between 1998 and 2007. Using a unique data from the Ministry of Environmental Protection, our analysis reveals that banking deregulation and increased loan inflows contribute to a reduction in toxic discharges. Rather than investing in pollution control technologies, firms leverage improved access to finance to enhance production efficiency and reduce energy consumption, which indirectly curbs emissions. These findings suggest that financial development promotes environmental benefits through technological advancement and asset reallocation, challenging the scale effect hypothesis.
JEL Codes: G2, G32, L25, L6, Q53
Assessing the Inner Setting among Massachusetts Community Health Centers: Opportunities for Multilevel Investigation and Expansion of Influences on Health Equity
Authors: LEE REBEKKA M , Daly James G. , Gundersen Dan , Lederman Ruth I. , Dargon-Hart Susan , Winickoff Jonathan P. , Emmons Karen M. 
Published: October 2024

Abstract

Background
Implementation science increasingly aims to improve equity in delivery of evidence-based interventions. It is important to expand the conceptualization of the inner setting, organizations like community health centers where interventions are put into place, accordingly. Taking a comprehensive, partnered approach to measuring the inner setting among a network of community health centers engaged in implementation research ensures assessment of the variability among sites and generates centralized contextual data that can be applied across studies.
Methods
We conducted a cross-sectional survey among staff (n = 63) from 12 community health centers in Massachusetts engaged in research at the Implementation Science Center for Cancer Control Equity. The survey assessed inner setting constructs from the Consolidated Framework for Implementation Research, including learning climate, leadership engagement, available resources, and implementation demands/stress using validated measures. Additional equity-focused inner setting items included structural characteristics of the work infrastructure and language access services. Descriptive statistics examined differences by staff role and health center.
Results
Staff rated learning climate (mean = 3.98) and leadership engagement (mean = 3.67) positively, while available resources (mean = 2.78) had the lowest rating, particularly staffing resources. Clinical staff rated the inner context lowest compared to other roles. Most centers provided tuition assistance and all reported supportive human resources benefits for caregiving, while fewer offered formal mentorship or affinity groups. Most community health centers reported written materials are routinely provided to patients in languages other than English and interpreter services were most common in Spanish, Vietnamese, and Portuguese.
Conclusions
This study provides a baseline assessment of the inner setting within Massachusetts community health centers. Periodic follow-up surveys will monitor changes over time. Data can be used in future analyses to explore how inner setting characteristics influence implementation outcomes and impact equitable translation of evidence-based interventions into practice.
Symptomatic gallbladder polyp: case report and literature review.
Authors: AFETANE Stéphane Arnaud AYEE , NAJIH Mohammed , Bouchentouf Sidi Mohammed 
Published: October 2024

Abstract

INTRODUCTION: Gallbladder polyps are a relatively common incidental finding during routine imaging studies. While the majority of these polyps are asymptomatic, a small subset can become symptomatic, leading to a variety of clinical presentations. We present a case of acute symptomatic polypoid lesion with macrolithiasis of the gallbladder initially presenting with equivocal clinical, laboratory, ultrasound and computer tomography findings. This case report aims to describe a patient with symptomatic gallbladder polyp and provide a review of the existing literature.CASE PRESENTATION: A 56-year-old Moroccan male with no particular past medical history presented with recurrent mild upper right quadrant pain with intermittent epigastric discomfort after meals. Generally, there were not fever. Diagnostic abdominal ultrasound undergone detected a macrolithiasis with posterior shadowing and thin wall of gallbladder. Computed Tomography showed evolution of a tissular nodular lesion at the bottom of the gallbladder. This subsequently demonstrated a mild gallbladder pseudotumor. The patient underwent laparoscopic cholecystectomy, and pathological examination of the specimen confirmed a benign gallbladder polyp.CONCLUSION Extemporaneous histology should be considered as to determine the various nature of polypoid lesions, particularly when ultrasound is equivocal or inconclusive, clinical and laboratory findings are non-specific. Hence symptomatic gallbladder polyps can present with variety of clinical manifestations.
Differential Associations of Subcutaneous and Visceral Fat with Bone Turnover Markers: A Study on Bariatric Surgery Patients with Severe Obesity and Individuals Without Obesity
Authors: Dadson Prince , Rebelos Eleni , Jaakkola Maria , Monfort-Pires Milena , Ojala Ronja , Honka Henri , Kalliokoski Kari , Klén Riku , Nuutila Pirjo , Ivaska Kaisa 
Published: October 2024

Abstract

Backgrounds
Obesity is associated with alterations in bone turnover markers (BTMs). However, the association between regional fat distribution and bone metabolism has received less attention. This study therefore aimed to identify which specific fat compartments (i.e., abdominal and femoral subcutaneous fat, intra- and extraperitoneal fat, and total visceral fat) exert the most significant influence on circulating BTMs.
Methods
The study comprised a cohort of individuals with severe obesity (n = 46), studied both before and after weigh loss induced by metabolic bariatric surgery, and individuals without obesity and surgery who served as controls (n = 25). The BTMs included Tartrate-Resistant Acid Phosphatase 5b, C-terminal Telopeptide of Type I Collagen (CTX), Procollagen Type I N-terminal Propeptide (PINP), and Total (TotalOC), Carboxylated (cOC), and Undercarboxylated (ucOC) osteocalcin.
Results
In the pooled data, significant negative associations were observed between intraperitoneal and total visceral fat and CTX, TotalOC, cOC, and ucOC (all with p < 0.05). Similarly, extraperitoneal fat showed a significant negative relationship with cOC. Conversely, no significant associations were observed between abdominal and femoral subcutaneous fat and any of the measured BTMs in the study participants (all p > 0.05).
Conclusions
Distinct deleterious implications for bone formation and resorption were associated with intraperitoneal, extraperitoneal, and total visceral fat. These findings emphasize the importance of fat distribution in the body to skeletal health.
ClinicalTrials.gov registration numbers: NCT00793143 and NCT01373892.
Laterally constrained inversion of time-domain transient electromagnetic data and its application to detecting water-rich zones in coal mines
Authors: Guo Yaofan , Xie Haijun , Li Gongyu , Li Jingrui , Liu Ruiqing , Liang Yongqi 
Published: October 2024

Abstract

During coal mining operations, water-rich aquifers within the height of developed water-conducting fracture zones pose significant safety risks. Identifying the extent of these water-rich zones in advance provides scientific basis for implementing water control measures. Transient electromagnetic method (TEM) is commonly used to detect these water-rich zones. However, due to the impact of turn-off time, the inversion accuracy of TEM data is reduced, hindering precise delineation of boundaries of these zones. To more accurately reflect actual water-rich properties of aquifers and achieve high-precision inversion results, this study investigated laterally constrained inversion (LCI) processes of the time-domain TEM data. Specifically, the ramp step within TEM turn-off time was divided into a series of vertical pulse responses, and the response formula of TEM-induced electromotive force was derived and analyzed. By establishing a terrestrial electricity model, forward modeling was performed to analyze characteristics of induced electromotive force response curves under different turn-off times of TEM and the impact of turn-off time on early resistivity. Based on pseudo-two-dimensional (2D) inversion of TEM data, full-time domain LCI of TEM data was carried out. The study showed that the longer the turn-off time, the greater the impact on early TEM signals. When the turn-off time was fixed, considering it in TEM inversion yielded results that more closely reflected actual geological conditions. Using practical engineering data, the results of conventional LCI inversion, full-time domain LCI inversion, and Interpex inversion of TEM data were compared. The results of full-time domain LCI inversion more accurately reflected the actual geological conditions. This work enhances the accuracy of detecting water-rich zones in coal mines, improving safety and water control measures.
A real-world study of clopidogrel therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention guided by individualized metabolic types
Authors: Li Zhilei , Li Yanpeng , Dong Huan , Cui Haodong , He Dongmei , Zhou Ziyuan , Yang Xiujuan , Zhang Xiaojuan 
Published: October 2024

Abstract

Purpose: To explore the relationship between adopting the recommendation for clopidogrel use based on genotype guidance in Acute Coronary Syndrome (ACS) patients undergoing Percutaneous Coronary Intervention (PCI) and the incidence of later cardiovascular ischemic and bleeding events.
Methods: A retrospective study was conducted on 3, 004 ACS patients treated with clopidogrel. Patients were grouped based on CYP2C19 genotype and followed for one year to record cardiovascular adverse and bleeding events.
Results: Adopting the recommendation for clopidogrel use can reduce the risk of total ischemic events in the intermediate metabolic group (Odds Ratio [OR], 0.676; P = 0.041). In the poor metabolic group, the recommendations could reduce the risk of in-stent stenosis/thrombosis (OR, 0.150; P = 0.035), revascularization (OR, 0.252; P = 0.048), and total ischemic events (OR, 0.350; P = 0.006). Individualized guidance based on the CYP2C19 genotype did not increase bleeding outcomes.
Conclusion:Individualized clopidogrel guidance based on genotype can reduce the ischemic risk in patients with intermediate and poor metabolizers, and the poor metabolic group benefits more. Individualized guidance did not increase bleeding outcomes in patients with intermediate or poor metabolizers.
Management of Subjects with Type 2 Diabetes Hospitalized in Internal Medicine Units: A Cluster-Randomized, Multicenter Study Before &amp; After an Educational Program
Authors: Ceriello Antonio , Fontanella Andrea , Attardo Tiziana Marcella , Beltramello Giampietro , Fierro Aldo , Prattichizzo Francesco , Pellegrini Valeria , Fiore Maria Serena , De Menis Ernesto , Maffettone Ada , Magnani Luigi , Pastorelli Ruggero , Ventrella Francesco , Rondana Massimo , Maurantonio Mauro , Scanferlato Mauro , Finizzola Francesco , Salvia Maria Antonia , Nevola Riccardo , Prampolini Giorgia , Laccetti Marco , Mastroianni Franco , Cartabellotta Fabio , Zagarri Elisa , Dentali Francesco , Manfellotto Dario 
Published: October 2024

Abstract

Introduction: Few data are available relatively to the adherence to treatment guidelines in individuals with type 2 diabetes mellitus (T2DM) admitted to Internal Medicine Wards (IMW) while no information is available relatively to the possible efficacy of an educational intervention aimed at implementing adherence in this setting.
Methods: To explore guidelines adherence and the relative impact on glycemic control in subjects with T2DM hospitalized in IMW before and after an educational intervention, we conducted a 3-phase, cluster-randomized, multicenter study. During phase 1, we retrospectively collected data from patients with T2DM hospitalized for any cause in IMW for ≥ 5 days. In phase 2, an educational training, based on the method of the educational outreach visits (EOV), was developed in 36 out of the 54 centers involved. In phase 3, done 6 months after the training, we replicated the collection of data performed in phase 1.
Results: Overall, we analyzed data from 1909 and 1662 individuals with T2DM during the phase 1 and phase 3 of the study, respectively. No changes were observed in the difference between mean fasting glycemia levels at discharge vs at admission at Phase 3 comparing EOV vs NO EOV groups. A statistically significant increase in adherence to guidelines was observed from Phase 1 to Phase 3 and a trend of higher adherence was detected when comparing the EOV and the no EOV groups. A structured educational intervention improves adherence to guidelines for managing T2DM in individuals admitted to IMW but has no effect on short-term glycemic control.
Brief report: Immune Checkpoint inhibitors use in lung cancer:A Real-World Outcome study in a middle-income country.
Authors: benbrahim zineb , Siyouri Oumaima , fetohi mohamed , benchakroun nadia , ismaili nabil , Bahra Nassiba , tachfouti nabil , ghissassi brahim el , mrabet Fatima zahra el , belbaraka Rhizlane , tahri ali , Acharqi Abdelkader , mellas Nawfel 
Published: October 2024

Abstract

Introduction
Lung cancer is the leading cause of cancer death in the world and its treatment represents a major challenge. Treatment with immune checkpoint inhibitors (ICIs) uses cutting-edge technologies and mobilizes a large number of clinical research players. However, the cost may be a barrier to access to these treatments in developing countries. The objective of this study was to evaluate the use of ICIs in lung cancer and assess real-world data of this treatment in Morocco.
Methods
This is a retrospective, multicenter cohort study conducted in a Moroccan population diagnosed with lung cancer between January 2019 and January 2022 and treated with ICIs. Patients were recruited from public and private oncology centers of the whole kingdom. Agreement of the ethics committee has been obtained. Survival data, response rates and time till discontinuation of treatment were evaluated using the chi-square test and bivariate analyzes.
Results
We included 158 cases representing 5 % of the total number of patients with advanced lung cancer who were eligible for treatment with ICIs. The mean age of patients was 62.48 years and the sex ratio (male/female) was of 4.41. Seventy percent of patient had non-squamous cell carcinoma. EGFR status was mutated in 3.9% of the cases. In 34.2% of the cases, the PD-L1 expression status was not known. Forty-seven percent of patients were treated with ICIs monotherapy. Fifty-eight percent of ICIs prescription was in the frontline treatment of lung cancer. The median time to discontinuation of treatment, was 13.53 months. The 12-month overall survival rate was 71.1%.The median overall survival was 17 months. The objective response rate was 40% with 9.3% of patients having grade 3 or 4 toxicities.
Conclusion
ICIs have demonstrated very good tolerance with durability of response and survival in a first real-world study dedicated to lung cancer in a developing country.
Identifying Burnout and Turnover Risks in Canadian Healthcare Workers During the COVID-19 Pandemic
Authors: Orr Taylor , Cheung Ellie , Saha Monidipa , Balogun Temilola , Feng Cindy , Farag Marwa 
Published: October 2024

Abstract

Background/Objectives: The COVID-19 pandemic has tested health systems worldwide, exposing significant weaknesses and vulnerabilities, particularly its toll on healthcare workers (HCWs). This study aimed to identify risk factors leading Canadian HCWs to consider leaving their positions due to stress or burnout during the pandemic.
Methods: Data from the 2022 Survey on Healthcare Workers’ Experiences During the Pandemic (SHCWEP) were analyzed using the Shanafelt and Noseworthy (2017) framework for understanding clinician burnout. We hypothesized that factors such as workload, work-life balance, resource availability, social and community support at work, and job environment—including organizational culture, values, and flexibility—could influence HCWs' intentions to leave due to stress or burnout. Multivariable logistic regression models were employed to identify significant risk factors for each HCW group.
Results: The SHCWEP survey had a 54.9% response rate, with 12,139 HCWs participating. Of these, 3,034 HCWs (25%) expressed an intention to leave their current job, and within this group, 1,350 cited stress or burnout as their reason, representing 11% of the total participants and 44% of those intending to leave. Factors associated with HCWs considering leaving due to stress and burnout included younger to middle-age, heightened work stress, longer working hours, increased workload, financial difficulties, conflicts with colleagues or management, non-adherence to PPE/IPC protocols, and lack of professional emotional support.
Conclusion: The findings align with the recommendations of the Framework for a Systems Approach to Clinician Burnout and Professional Well-Being. Many factors contributing to HCWs' intentions to leave due to stress or burnout could be mitigated by policymakers and health organizations.