bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human resource management and performance at the Indian Railways
Authors: Pereira Vijay Edward , Fontinha Rita , Budhwar Pawan , Arora Bimal 
Published: February 2018

PurposeHigh-performance work practices (HPWPs) have been well documented within private organisations in developed country economies. Such practices, however, remain under-investigated in the public sector and in emerging economies. The purpose of this paper is to work towards filling this void, by empirically evaluating HPWP within an Indian public sector undertaking (PSU), also the world’s largest commercial public sector employer: the Indian Railways (IR).Design/methodology/approachThe authors investigate whether the practices implemented in this organisation are consistent with the idea of HPWPs, and analyse how they are influenced by different stakeholders and ultimately associated with different indicators of organisational performance. The authors focused on six railway zones and interviewed a total of 62 HR practitioners.FindingsThe results show that most practices implemented are aligned with the idea of HPWPs, despite the existence of context-specific unique practices. Furthermore, the authors identify the influence of multiple stakeholders in decision making concerning different practices. The authors additionally found that the measurement of performance goes beyond financial indicators and several context-specific non-financial indicators are identified and their social importance is reiterated.Originality/valueTheoretically, this paper utilises and contributes to the resource-based view of firms by identifying a distinctive bundle of competencies in human resources through HPWS in the IR.
Life enrichment for workers in contemporary China
Authors: Zhao Yang , Fujimoto Yuka , Gaur Sanjaya Singh 
Published: February 2018

Purpose
The purpose of this paper is to identify key antecedents of work-family enrichment (WFE) for Chinese workers in China. The paper adopts the Chinese cultural perspectives (i.e. philosophy of Confucian: Chinese family orientation and collectivism) as well as traditional Chinese philosophies of life as a whole.

Design/methodology/approach
This is a conceptual paper. Therefore, this section does not apply.

Findings
The key antecedents of Chinese WFE have been identified and presented in the conceptual framework. Testable propositions have also been developed and presented in this paper.

Practical implications
The conceptual framework showing the identified key antecedents of Chinese WFE highlights the necessity for the corporate leaders to rethink the ways to promote well-being and productivity of Chinese workforce in China. Meanwhile, managers should rethink about WFE among Chinese employees and regard employees as a whole person rather than just a worker with certain skills or abilities.

Originality/value
This is the first paper to propose the concept of life enrichment by examining the antecedents of WFE particularly from the Chinese philosophical and cultural perspective.
Epilogue – service innovation actor engagement: an integrative model
Authors: Hollebeek Linda D. , W. Andreassen Tor , Smith Dale L.G. , Grönquist Daniel , Karahasanovic Amela , Márquez Álvaro 
Published: February 2018

Purpose
While (customer) engagement has been proposed as a volitional concept, our structuration theory/S-D logic-informed analyses of actors’ (e.g. employees’) engagement in service innovation reveal engagement as a boundedly volitional theoretical entity, which arises from actors’ structural and agency-based characteristics and constraints. In line with this observation, the purpose of this paper is to develop a conceptual model of actor (i.e. customer, firm, employee) engagement with service innovation.

Design/methodology/approach
Based on the observed gap, the authors propose an integrative S-D logic/structuration theoretical model that outlines three particular service innovation actors’ (i.e. customers’, the firm’s and employees’) engagement, which comprises institution-driven (i.e. fixed) and agency-driven (i.e. variable) engagement facets. In addition, the authors integrate the key expected characteristics of positively (vs negatively) valenced service innovation engagement for each of these actor groups in the analyses.

Findings
The authors develop a 12-cell matrix (conceptual model) that outlines particular service innovation actors’ institution-driven and agency-driven engagement facets and outline their expected impact on actors’ ensuing positively and negatively valenced engagement.

Research limitations/implications
The authors discuss key theoretical implications arising from the analyses.

Originality/value
Outlining service innovation actors’ structure- and agency-driven engagement facets, the authors’ model can be used to explain or predict customers’, the firm’s or employees’ service innovation engagement-based activities.
Analytical study of crowdsourced GLAM digital repositories
Authors: Gupta Dinesh K. , Sharma Veerbala 
Published: February 2018

Purpose
The purpose of this paper is to find out the status/levels of using crowdsourcing in galleries, libraries, archives and museums (GLAM) around the globe and to give suggestions on how Indian GLAM can take the benefit of this global trend.

Design/methodology/approach
The study is based on the analytical study of the literature available on the embracing crowdsourcing for diverse tasks with special emphasis on the efforts of GLAM domain regarding the development of digital repositories.

Findings
Meticulous analysis of literature and case studies give an overview of the diverse practices of public participation/crowd collaboration in the development of digital repositories around the globe. However, Indian GLAM are far behind in adopting such practices.

Practical implications
With the rapid growth in digital information and Web-based technology, GLAM around the world encourage and engage public participation in various digitization projects to enrich and enhance their digital collections and place them on the Web. However, Indian GLAM still refrain to accept and adopt such practices. Thus, this paper will encourage and motivate the Indian GLAM to enrich and enhance their collection with crowd contribution and uploading them on Web.

Originality/value
This is an original paper and has great implementation value. During the study, enormous literature was available on crowd participation in various areas around the globe, as well as in India. International examples of crowd participation in GLAM creation are found in the literature; however, not sufficient evidences are found regarding crowd contribution in Indian GLAM. Hence, the paper, by presenting the evidences of crowd participation in GLAM domain, proposes the Indian GLAM to exploit the benefits of this practice for Indian digital repositories to expedite the creation and development of various national digital repositories.
A cross-country comparison of green initiatives, green performance and financial performance
Authors: Chen Fang , Ngniatedema Thomas , Li Suhong 
Published: February 2018

PurposeThe purpose of this paper is to investigate the relationship between green initiatives, green performance, and a firm’s financial performance in the world. The existing literature on environmental initiatives and their impacts is limited to the context of a particular country. This gap points to a lack of clarification of variations in environmental regulation and in economic disparity which may affect the impact of green initiatives on green performance and on financial performance.Design/methodology/approachData on the world top 500 publicly traded companies are collected from Compustat, a database of financial, statistical and market information on global companies, and from Newsweek, an information gatekeeper that enables consumers to access a list of environmentally friendly companies. The paper adopts linear regression to test the relationships between variables.FindingsThe results show that green initiatives have a positive impact on green performance, which in turn has a positive impact on financial performance. However, the impact of green initiatives varies by country. The study revealed that companies in European countries and Canada lead in the green initiatives and green performance, followed by the USA and Japan. China and Hong Kong lag behind compared to other countries.Research limitations/implicationsThe small sample size in some of the countries used in this study may impact the validity of the results.Practical implicationsThis study suggests that companies that seek financial benefits of pursuing green initiatives should have a long-term orientation when implementing these initiatives and should consider the country where they operate.Originality/valueThe current study provides a global understanding of the relationship between green initiatives, green performance, and financial performance, and contributes to the literature by highlighting variation among countries and by year.
Mapping the sharing economy for sustainability research
Authors: Plewnia Frederik , Guenther Edeltraud 
Published: February 2018

Purpose
In order to guide sustainability research on the sharing economy, the purpose of this paper is to develop a comprehensive framework that captures the wide range of activities and business models that are considered to be part of the sharing economy.

Design/methodology/approach
Based on a systematic literature review and a content analysis, existing typologies are identified and analyzed for their conceptual intersections. Finally, categorizations from 43 documents are integrated into one framework.

Findings
Four main dimensions are identified as being used in different contexts to characterize sharing systems and were combined to form one comprehensive typology: shared good or service, market structure, market orientation, and industry sector.

Originality/value
The proposed typology is able to distinguish sharing activities based on their similarities and differences. Social, economic, and communicational avenues for the term “sharing” are merged into a conceptual foundation of the sharing economy. This enables researchers, practitioners, and policy makers to position their projects in the broad field of sharing. By discussing inherent tensions with regard to sustainability of the sharing economy, the offered categorizations can help to guide future research and policy intervention. Last but not least, professional managers should find valuable ideas for new business models.
Use of the Nursing Outcomes Classification for Falls and Fall Prevention by Nurses in South Korea
Authors: Lee Eunjoo 
Published: February 2018

PURPOSETo estimate the use of the Nursing Outcomes Classification (NOC) for falls and fall prevention.METHODSThis cross‐sectional, descriptive study enrolled 196 registered nurses in South Korea.FINDINGSOutcome assessments for falls and fall prevention were performed for 30–50% of hospitalized patients. The NOC outcomes related to falls and fall prevention were used more in surgical units than medical units.CONCLUSIONSThe performance rates of the outcomes related to falls and fall prevention were not high in hospitalized patients.IMPLICATIONS FOR NURSING PRACTICEStrategies should be developed to increase the use of the NOC by nurses for fall prevention. In this way, nurses’ contributions to patient outcomes would be recognized and the safety of patients would be enhanced.
Agronomic, forage quality and economic advantages of red pea (Lathyrus cicera L.) intercropping with wheat and oat under low‐input farming
Authors: Vlachostergios D. N. , Lithourgidis A. S. , Dordas C. A. 
Published: February 2018

AbstractRed pea–cereal intercropping could provide animal feed with agronomic and economic advantages. The growth rate, forage yield, quality, interspecific competition and financial outcome of intercrops of red pea (Lathyrus cicera L.) with wheat (Triticum aestivum L.) and oat (Avena sativa L.) in two different seeding ratios (60:40, 80:20) were estimated. Growth rate of species was lower in the intercrops than in monocrops, especially in red pea–oat intercrops due to the strong competitive ability of oat. Red pea–oat intercrop of 60:40 produced the highest biomass (10.83 Mg/ha) and crude protein yield (1,116 kg/ha). Land equivalent ratio (LER) values were greater for the red pea with wheat (1.13) and oat 60:40 (1.09) indicating an advantage of intercropping in terms of dry‐matter (DM) yield, while red pea:oat 60:40 ranked first for LER for nitrogen yield. Aggressivity and partial actual yield loss indicated cereals as the dominant species. The highest monetary advantage index was recorded for the red pea:wheat 60:40 and the highest intercropping advantage value was recorded for the red pea:oat 80:20. In conclusion, most intercrops of red pea with wheat and oat showed significant advantages relative to their monocrops due to better DM production, resource‐use efficiency and economics under low‐input farming.
Chronic myeloid leukaemia and tyrosine kinase inhibitor therapy: assessment and management of cardiovascular risk factors
Authors: Ross David M. , Arthur Chris , Burbury Kate , Ko Brian S. , Mills Anthony K. , Shortt Jake , Kostner Karam 
Published: February 2018

AbstractSeveral BCR‐ABL1 tyrosine kinase inhibitors (TKIs) are approved for the first‐line treatment of chronic phase chronic myeloid leukaemia (CML). Disease control is achieved in the vast majority of patients and disease‐specific survival is excellent. Consequently, there is now emphasis on managing comorbidities and minimising treatment‐related toxicity. Second‐generation TKIs have cardiovascular risks that are greater than with imatinib treatment, but these risks must be balanced against the superior CML responses encountered with more potent TKIs. Cardiovascular risk should be assessed at baseline using a locally validated model based on the Framingham risk equation. Clinicians involved in the care of CML patients should be aware of the vascular complications of TKIs and manage cardiovascular risk factors early to mitigate treatment‐related risks. Reversible risk factors, such as dyslipidaemia, smoking, diabetes and hypertension, should be addressed. We summarise the available data on cardiovascular complications in CML patients treated with TKIs. Using the latest evidence and collective expert opinion, we provide practical advice for clinicians to assess, stratify and manage cardiovascular risk in people with CML receiving TKI therapy.
Community‐Level Exposure to the Rural Mining Industry: The Potential Influence on Early Adolescent Alcohol and Tobacco Use
Authors: Gay Christopher , Clements‐Nolle Kristen , Packham John , Ackerman Gerald , Lensch Taylor , Yang Wei 
Published: February 2018

AbstractPurposeRural youth have higher rates of alcohol and tobacco use compared to their urban counterparts. However, the economic dependence of rural communities may differentially influence risk behaviors. While research has shown that adults working in mining have elevated rates of alcohol and tobacco use, the influence of living in a mining community on early adolescent substance use is unknown.MethodsUsing data from a representative sample of 4,535 middle school students in a state with heavy reliance on mining, we conducted weighted logistic regression to investigate whether community‐level mining economic dependence influences rural‐urban differences in adolescent alcohol and tobacco use. All models adjusted for sociodemographics, military family involvement, parental monitoring, and length of residence.FindingsOver one quarter of the sampled students lived in rural counties and approximately half of these counties met the USDA mining economic typology. After stratifying rural counties by mining and nonmining economic dependence, students in rural mining counties had significantly higher odds of all measures of alcohol use (AORs ranged from 1.83 to 3.99) and tobacco use (AORs ranged from 1.61 to 5.05) compared to students in urban counties. Only use of smokeless tobacco was higher among students in rural nonmining counties.ConclusionsOur findings demonstrate rural‐urban disparities in adolescent substance use that are particularly pronounced among youth living in counties with economic dependence on mining. Future research on this subject should include a wider range of community‐level factors that may have specific relevance in rural settings to inform the development of population‐level interventions.
Structure and ontogeny of successive cambia in Tetrastigma (Vitaceae), the host plants of Rafflesiaceae
Authors: Pace Marcelo R. , Angyalossy Veronica , Acevedo‐Rodríguez Pedro , Wen Jun 
Published: February 2018

AbstractSuccessive cambia in Vitaceae have been reported solely for Tetrastigma, a diverse genus of lianas found primarily in tropical Asia, extending into Australia. However, the structure and origin of these successive cambia have never been fully studied. Here we report the presence of this cambial variant in Tetrastigma retinervum and T. voinierianum, and describe its ontogeny in detail in the latter. New cambia appear successively in stems of Tetrastigma differentiating from the innermost parenchyma cells of the primary phloem, which are located interior to the pericyclic fiber strands. This study constitutes the first report of successive cambia being derived from primary phloem parenchyma in woody plants as a whole. Both species are members of Tetrastigma clade VI, the most species‐rich lineage within the genus. The examination of mature stems of additional species of Tetrastigma should determine the distribution of this unique type of cambial variant in the genus and enhance our understanding of the adaptive significance of this unusual character.
Specific substitutions of light‐harvesting complex I proteins associated with photosystem I are required for supercomplex formation with chloroplast NADH dehydrogenase‐like complex
Authors: Otani Takuto , Kato Yoshinobu , Shikanai Toshiharu 
Published: February 2018

SummaryIn Arabidopsis, the chloroplast NADH‐dehydrogenase‐like (NDH) complex is sandwiched between two copies of photosystem I (PSI) supercomplex, consisting of a PSI core and four light‐harvesting complex I (LHCI) proteins (PSI‐LHCI) to form the NDH–PSI supercomplex. Two minor LHCI proteins, Lhca5 and Lhca6, contribute to the interaction of each PSI–LHCI copy with the NDH complex. Here, large‐pore blue‐native gel electrophoresis revealed that, in addition to this complex, there were at least two types of higher‐order association of more LHCI copies with the NDH complex. In single‐particle images, this higher‐order association of PSI–LHCI preferentially occurs at the left side of the NDH complex when viewed from the stromal side, placing subcomplex A at the top (Yadav et al., Biochim. Biophys. Acta ‐ Bioenerg., 1858, 2017, 12). The association was impaired in the lhca6 mutant but not in the lhca5 mutant, suggesting that the left copy of PSI–LHCI was linked to the NDH complex via Lhca6. From an analysis of subunit compositions of the NDH–PSI supercomplex in lhca5 and lhca6 mutants, we propose that Lhca6 substitutes for Lhca2 in the left copy of PSI–LHCI, whereas Lhca5 substitutes for Lhca4 in the right copy. In the lhca2 mutant, Lhca3 was specifically stabilized in the NDH–PSI supercomplex through heterodimer formation with Lhca6. In the left copy of PSI–LHCI, subcomplex B, Lhca6 and NdhD likely formed the core of the supercomplex interaction. In contrast, a larger protein complex, including at least subcomplexes B and L and NdhB, was needed to form the contact site with Lhca5 in the right copy of PSI–LHCI.
Systematic Review and Meta-analysis of the Safety of Antistaphylococcal Penicillins Compared to Cefazolin
Authors: Eljaaly Khalid , Alshehri Samah , Erstad Brian L. 
Published: February 2018

ABSTRACT

Recent studies and experience suggest that cefazolin might be equally as effective as antistaphylococcal penicillins for methicillin-susceptible
Staphylococcus aureus
(MSSA), with a better safety profile and lower cost. The objective of these meta-analyses was to compare the safeties of antistaphylococcal penicillins and cefazolin. The PubMed, Embase, and International Pharmaceutical Abstracts databases and websites for clinical trial registries through 23 June 2017 were searched. In addition, recent abstracts from infectious disease and pharmacy conferences were reviewed. We estimated Peto odds ratios (ORs) with 95% confidence intervals (CIs) using random-effects models. One analysis focused on hospitalized patients, and the other focused on outpatients. Eleven retrospective studies of hospitalized patients and three retrospective studies of outpatients were included. In hospitalized patients, lower rates of nephrotoxicity (Peto OR, 0.225; 95% CI, 0.127 to 0.513), acute interstitial nephritis (Peto OR, 0.189; 95% CI, 0.053 to 0.675), hepatotoxicity (Peto OR, 0.160; 95% CI, 0.066 to 0.387), and drug discontinuation due to adverse reactions (Peto OR, 0.192; 95% CI, 0.089 to 0.414) were found with cefazolin. In outpatients, lower rates of nephrotoxicity (Peto OR, 0.372; 95% CI, 0.192 to 0.722), hepatotoxicity (Peto OR, 0.313; 95% CI, 0.156 to 0.627), and hypersensitivity reactions (Peto OR, 0.372; 95% CI, 0.201 to 0.687) were observed with cefazolin. Compared to antistaphylococcal penicillins, cefazolin was associated with significant reductions in nephrotoxicity and hepatotoxicity in hospitalized patients and outpatients. Additionally, cefazolin was associated with lower likelihoods of discontinuation due to side effects in hospitalized patients and hypersensitivity reactions in outpatients. Cefazolin should be considered a first-line option for patients with MSSA infections for which efficacy is presumed to be similar to that of antistaphylococcal penicillin therapy.
In Vitro
and
In Vivo
Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens
Authors: Purnapatre Kedar P. , Rao Madhvi , Pandya Manisha , Khanna Alka , Chaira Tridib , Bambal Ramesh , Upadhyay Dilip J. , Masuda Nobuhisa 
Published: February 2018

ABSTRACT

The emergence of multidrug-resistant (MDR) Gram-negative bacilli is a major concern in the treatment of nosocomial infections. Antibacterial agents with novel modes of action can be useful, as these pathogens have become resistant to almost all existing standard-of-care agents. GSK2251052, a leucyl-tRNA synthetase inhibitor, has a novel mode of action against Gram-negative bacteria. However, the phase 2 studies with this drug were terminated due to microbiological failures based on the rapid emergence of drug resistance during the treatment of complicated urinary tract infections. DS86760016 is a novel leucyl-tRNA synthetase inhibitor active against MDR Gram-negative bacteria, such as
Escherichia coli
,
Klebsiella pneumoniae
, and
Pseudomonas aeruginosa
, with an improved pharmacokinetic profile. DS86760016 showed lower plasma clearance, longer plasma half-life, and higher renal excretion than GSK2251052 did in mice, rats, monkeys and dogs. DS86760016 also showed lower mutant prevention concentrations against
P. aeruginosa
than did GSK2251052. No resistant bacteria were observed in murine urinary tract infection models at a dose that maintained urinary concentrations above the mutant prevention concentration. DS86760016 also showed a lower risk of resistance development than did GSK2251052 in comparative
in vivo
studies with murine urinary tract infection models. These results suggest that DS86760016 has potential as a new drug for the treatment of MDR Gram-negative bacterial infections, with a lower risk of drug resistance development than that of GSK2251052.