bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Rising Frequency of IT Blackouts Indicates the Increasing Relevance of IT Emergency Concepts to Ensure Patient Safety
Authors: Sax U. , Lipprandt M. , Röhrig R. 
Published: November 2016

Summary
Introduction: As many medical workflows depend vastly on IT support, great demands are placed on the availability and accuracy of the applications involved. The cases of IT failure through ransomware at the beginning of 2016 are impressive examples of the dependence of clinical processes on IT. Although IT risk management attempts to reduce the risk of IT blackouts, the probability of partial/total data loss, or even worse, data falsification, is not zero. The objective of this paper is to present the state of the art with respect to strategies, processes, and governance to deal with the failure of IT systems.
Methods: This article is conducted as a narrative review.
Results: Worst case scenarios are needed, dealing with methods as to how to survive the downtime of clinical systems, for example through alternative workflows. These workflows have to be trained regularly. We categorize the most important types of IT system failure, assess the usefulness of classic counter measures, and state that most risk management approaches fall short on exactly this matter.
Conclusion: To ensure that continuous, evidence-based improvements to the recommendations for IT emergency concepts are made, it is essential that IT blackouts and IT disasters are reported, analyzed, and critically discussed. This requires changing from a culture of shame and blame to one of error and safety in healthcare IT. This change is finding its way into other disciplines in medicine. In addition, systematically planned and analyzed simulations of IT disaster may assist in IT emergency concept development.
Findings from the Section on Bioinformatics and Translational Informatics
Authors: Dauchel H. , Lecroq T. 
Published: November 2016

Summary
Objective: To summarize excellent current research and propose a selection of best papers published in 2016 in the field of Bioinformatics and Translational Informatics with applications in the health domain and clinical care.
Methods: We provide a synopsis of the articles selected for the IMIA Yearbook 2017, from which we attempt to derive a synthetic overview of current and future activities in the field. As in 2016, a first step of selection was performed by querying MEDLINE with a list of MeSH descriptors completed by a list of terms adapted to the section coverage. Each section editor evaluated separately the set of 951 articles returned and evaluation results were merged for retaining 15 candidate best papers for peer-review.
Results: The selection and evaluation process of papers published in the Bioinformatics and Translational Informatics field yielded four excellent articles focusing this year on the secondary use and massive integration of multi-omics data for cancer genomics and non-cancer complex diseases. Papers present methods to study the functional impact of genetic variations, either at the level of the transcription or at the levels of pathway and network.
Conclusions: Current research activities in Bioinformatics and Translational Informatics with applications in the health domain continue to explore new algorithms and statistical models to manage, integrate, and interpret large-scale genomic datasets. As addressed by some of the selected papers, future trends would include the question of the international collaborative sharing of clinical and omics data, and the implementation of intelligent systems to enhance routine medical genomics.
Pleiotropic Effects of Loss of the Dα1 Subunit in Drosophila melanogaster: Implications for Insecticide Resistance
Authors: Somers Jason , Luong Hang Ngoc Bao , Mitchell Judith , Batterham Philip , Perry Trent 
Published: November 2016

Abstract
Nicotinic acetylcholine receptors (nAChRs) are a highly conserved gene family that form pentameric receptors involved in fast excitatory synaptic neurotransmission. The specific roles individual nAChR subunits perform in Drosophila melanogaster and other insects are relatively uncharacterized. Of the 10 D. melanogaster nAChR subunits, only three have described roles in behavioral pathways; Dα3 and Dα4 in sleep, and Dα7 in the escape response. Other subunits have been associated with resistance to several classes of insecticides. In particular, our previous work has demonstrated that an allele of the Dα1 subunit is associated with resistance to neonicotinoid insecticides. We used ends-out gene targeting to create a knockout of the Dα1 gene to facilitate phenotypic analysis in a controlled genetic background. To our knowledge, this is the first report of a native function for any nAChR subunits known to be targeted by insecticides. Loss of Dα1 function was associated with changes in courtship, sleep, longevity, and insecticide resistance. While acetylcholine signaling had previously been linked with mating behavior and reproduction in D. melanogaster, no specific nAChR subunit had been directly implicated. The role of Dα1 in a number of behavioral phenotypes highlights the importance of understanding the biological roles of nAChRs and points to the fitness cost that may be associated with neonicotinoid resistance.
Twitter in Education: Perceptions of Pre-Service Teachers
Authors: Kalelioglu Filiz 
Published: November 2016

The aim of this study is to determine the perceptions of students about the use of Twitter within education. Participants of the study were 17 junior class Education Faculty students from the Computer Education and Instructional Technology Department at a private university in Turkey. At the beginning of the course, the instructor requested students to sign up for Twitter and follow her tweets. Then the instructor created a hashtag for the lesson and over the duration of the course, shared course announcements and related papers using this hashtag. Students also tweeted about summary course content covered during face-to-face lessons. At the end of the course, a questionnaire captured studentsâ€™ perceptions about the use of Twitter within education through five open-ended questions. Content analysis was applied to analyse the qualitative data.

Keywords: Twitter, microblogging, perceptions, pre-service teachers
Quality Standards in eLearning: A matrix of analysis
Authors: Frydenberg Jia 
Published: November 2016

<p>
Most institutions of postsecondary and higher education are creating or adopting quality statements, standards, and criteria regarding their niche of the “eLearning enterprise.” In doing so, they have a tendency to reinvent the wheel. This article summarizes current published quality standards in the US, and analyzes and organizes them into a nine-cell matrix. It concludes with discussion of emerging issues with respect to the nine standards-areas.
</P>

<P><B>Key Terms:</B> ELearning, online learning, Web-based learning, quality standards; development, delivery and support of online learning</P>
Prevalence of Underweight, Overweight, and Obesity Among Reproductive-Age Women and Adolescent Girls in Rural China
Authors: He Yuan , Pan An , Yang Ying , Wang Yuanyuan , Xu Jihong , Zhang Ya , Liu Dujia , Wang Qiaomei , Shen Haiping , Zhang Yiping , Yan Donghai , Peng Zuoqi , Hu Frank B. , Ma Xu 
Published: November 2016

Objectives. To provide prevalence and trends of underweight, overweight, and obesity among reproductive-age women and adolescent girls in rural China. Methods. We measured weight and height in 16 742 344 women aged 20 to 49 years and 178 556 girls aged 15 to 19 years from the National Free Preconception Health Examination Project between 2010 and 2014. Results. Among women, the prevalence of underweight was 7.8% (95% confidence interval [CI] = 7.7%, 7.9%), and overweight or obesity was 16.5% (95% CI = 16.4%, 16.6%; World Health Organization criteria). Among adolescents, prevalence of underweight was 6.0% (95% CI = 5.7%, 6.2%; Centers for Disease Control and Prevention criteria) and overweight or obesity was 8.3% (95% CI = 7.9% to 8.8%; International Obesity Task Force criteria). According to Chinese criteria, overweight and obesity prevalence was 24.8% (95% CI = 24.7%, 24.9%) for women and 17.2% (95% CI = 16.6%, 17.8%) for adolescents, and underweight prevalence was 2.9% (95% CI = 2.8%, 3.1%) for adolescents. Considerable disparities existed in prevalence and trends within subpopulations (age groups, parity, region, education levels, and socioeconomic status). Conclusions. Our results reveal coexisting underweight and overweight or obesity among rural women and adolescents of reproductive age, which requires public health attention.
The Extent of Manure Removal from Storages and Its Impact on Gaseous Emissions
Authors: Ngwabie N. M. , Gordon R. J. , VanderZaag A. , Dunfield K. , Sissoko A. , Wagner‐Riddle C. 
Published: November 2016

Manure remaining in storage due to incomplete removal is a source of microbial inoculum that may affect methane (CH4), nitrous oxide (N2O), and ammonia (NH3) emissions during subsequent storage. Manure removal was studied by loading fresh manure into outdoor concrete tanks (10.6 m3) that contained previously stored manure (inoculum) at six levels (0, 5, 10, 15, 20, and 25%, with 0% representing an empty tank). Emissions were continuously measured for 6‐mo storage periods (warm and cold seasons) using flow‐through chambers. Fluxes during the warm season (average manure temperature at 80 cm depth, Tm = 17°C) were 25 times higher for CH4, 20 times higher for N2O, and 2.9 times higher for NH3 compared with the cold season (Tm = 4°C). Cumulative CH4 emissions increased linearly with the level of added inoculum in the cold season (r2 = 0.98). A similar linear increase was observed in the warm season from 0 to 20% inoculum (r2 = 0.91), after which a decrease in emissions was observed at 25%. Reducing inoculum from 15 to 5% reduced CH4 emissions by 26% in the warm season and 45% in the cold season. There was no clear effect of inoculum on N2O and NH3 emissions, suggesting that complete manure storage emptying does not alter their emissions.Core Ideas
Manure in storage from incomplete removal is a source of microbial inoculum affecting CH4 emissions.
Cumulative CH4 emissions increased linearly with the level of added inoculum in the cold season.
Cumulative CH4 emissions increased linearly from 0 to 20% inoculum in the warm season.
Reducing inoculum from 15 to 5% reduced CH4 emissions in warm season by 26% and cold season by 45%.
PENGEMBANGAN E-LEARNING BERBASIS PENDEKATAN ILMIAH PADA MATA PELAJARAN IPA DI SMP NEGERI 5 YOGYAKARTA
Authors: Mu'arif Heru Amrul , Surjono Herman Dwi 
Published: November 2016

Penelitian ini bertujuan untuk: (1) menghasilkan produk e-learning berbasis pendekatan ilmiah pada mata pelajaran Ilmu Pengetahuan Alam bagi siswa kelas VIII SMP Negeri 5 Yogyakarta dengan spesifikasi model dan isi yang ditetapkan, (2) mengetahui kelayakan produk e-learning, (3) mengetahui hasil belajar siswa setelah menggunakan e-learning. Jenis penelitian ini adalah penelitian dan pengembangan (R&D) dan diadaptasi dari model Alessi dan Trollip. Prosedur pengembangan meliputi tahap perencanaan, desain, dan pengembangan. Hasil Penelitian menunjukan sebagai berikut: (1) produk e-learning berbasis pendekatan ilmiah berhasil dikembangkan dengan sebuah sistem manajemen pembelajaran (LMS) online yang dibuat dengan software aplikasi moodle. E-learning berbasis pendekatan ilmiah dikembangkan untuk pokok bahasan sistem tata surya dan kehidupan di bumi; (2) produk e-learning berbasis pendekatan ilmiah pada mata pelajaran ilmu pengetahuan alam telah memenuhi kriteria dan dinyatakan layak sebagai media pembelajaran berdasarkan validasi ahli media, ahli materi, dan siswa, kelayakannya mencapai rerata skor 4,15 dengan kategori baik; (3) keefektifan pembelajaran IPA lebih baik setelah menggunakan e-learning dibuktikan melalui peningkatan hasil belajar. Hasil belajar siswa kelas VIII SMP Negeri 5 Yogyakarta mengalami peningkatan setelah menggunakan e-learning.Kata kunci: e-learning, pendekatan ilmiah, ilmu pengetahuan alam. DEVELOPING OF E-LEARNING BASED ON SCIENTIFIC APPROACH ON NATURAL SCIENCES LESSON AT SMPN 5 YOGYAKARTAAbstractThis study aims to: (1) develop e-learning based on scientific approaches on natural science subjects for students grade VIII of SMPN 5 Yogyakarta with model specifications and specified contents, (2) determine the feasibility of e-learningproduct (3) determine student learning achievement after using e-learning. This research was a research and development (R&D) adapted from models of Alessi &Trollip. The development procedure included the planning, design, and development. This study shows the following results. (1) E-learning-based on scientificapproaches was developed with a learning management system (LMS) online software applications created with Moodle. E-learning is developed based on a scientific approach for the subject of the solar system and life on Earth; (2) e-learning based on scientific approaches for natural science subjects is appropriate as a medium of learning based on the judgement from media expert, materials experts, and students, with the feasibility with mean score of 4.15 with both categories; (3) the learning achievement of class VIII student of SMPN 5 Yogyakarta increases after using e-learning.Keywords: e-learning, scientific approach, natural sciences
Installing a Jacket Structure Over a Subsea Wellhead with a Jack Up Rig
Authors: Damasena Edwin , Safar Ronald , Sampurno Sonny T 
Published: November 2016

Abstract
Kambuna field is located offshore Strait of Malaka East of Belawan the Port of Medan in North Sumatera. Kambuna is the first field development for Asia Petroleum Development (Serica Energy). Kambuna development is contracted to Asia Petroleum under a Technical Assistance Contract with Pertamina. A minimum size unmanned Wellhead Tripod Structure was secured with three conductor piles. The previous Operator of the field opted to suspend the exploration discovery subsea well drilled with a semi submersible in 2006 for later use as a producer well. Hence the Tripod Jacket had to be lowered over the Subsea Wellhead with no other guidance provided by a pipe or structure as is normally the case, except for a Remote Operated Vehicle for monitoring purposes. Novel installation technique was developed and used for this unusual structure installation including docking the structure mudmat around the subsea wellhead. Very accurate rig positioning relative to the subsea wellhead was critical for the success of the installation. It is believed that the concept of free descending the Jacket Structure using a JU rig and to capture the Subsea Wellhead underwater with no guide string was never done before. Following successful Jacket installation, the 3× 30 in conductor piles were then driven through the 36 in diameter legs of the structure to 80 m below the seabed then cemented to surface. Two wells were drilled through the conductor piles and the Subsea Wellhead tied back to surface. The cost of drilling and completion a new development well is hereby saved by re-utilisation of a suspended subsea exploration well. Off the critical path work procedure was developed resulting in significant rig time saving. Tripod jacket structure installation over a Subsea Wellhead technique is described in this paper.
Laboratory Evaluation of Chemical EOR Process for Viscous and High EACN Oil in East African Oilfields
Authors: Foo Y. Y. , Tewari R. D. , Kok K. C. , Elrufai A. , Elbaloula H. , Elkheir L. 
Published: November 2016

Abstract
Poor conformance and unfavourable mobility ratio in the reservoir are common issues that hinder effective oil production and recovery. These issues are often exacerbated when the displacement is associated with viscous oil driven by water in highly permeable porous media. One of the reservoirs located onshore in East Africa suffers from this issue of high bypassed oil due to the presence of viscous oil, i.e. viscosity of 20 cP and API gravity of 28°. Most of the produced wells were observed to experience early water breakthrough and suffered from high water cut at present. In view of this phenomenon, Alkaline-Surfactant-Polymer (ASP) flooding was proposed to recover the remaining oil that is bypassed and trapped underneath. Through laboratory evaluation, the main objective of this study was to generate an effective chemical concoction comprising of alkaline, polymer and surfactant which are compatible to the formation fluids and rocks for the targeted reservoirs. The laboratory works were conducted based on a comprehensive and systematic workflow. Sample characterization and fluid-fluid analysis at the early phase encompass the studies of phase behaviours, physico-chemical properties, thermal stability etc. These studies aimed to screen off the chemical candidates which did not fulfill the corresponding Key Performance Indicators (KPI). The successful ASP formulations were subsequently optimized in terms of their respective concentrations without sacrificing the technical performance. Fluid-rock analysis aimed to quantify the oil recovery potential and reduction of residual oil saturation through coreflood experiments. Due to the high Equivalent Alkane Carbon Number (EACN) of the crude oil, i.e. 19 (nonadecane), and ultra-low salinity of formation water, i.e. 950 ppm, the greatest technical challenge in this study was to identify an effective surfactant which could reduce the water-oil interfacial tension (IFT) significantly under the operating range. Despite the challenges, an optimized ASP formulation, with a concentration of 0.5 wt.% of alkali, 0.2 wt.% of surfactant and 0.2 wt.% of polymer, successfully fulfilled all of the required KPI. The coreflood results indicate a reduction of residual oil saturation more than 30 % of Oil-In-Place. With these encouraging laboratory results, it could lead to the prospect of pilot and detailed Field Development Plan (FDP) studies, which could further de-risk the chemical EOR projects in this region.
Assessment of the Volumetric Distribution of Natural Tectonic Fractures within a Tight Matrix Carbonated Reservoir Using Geomechanical Attributes: Application to Najmah-Sargelu Units, West Kuwait
Authors: Al-Muraikhi Rasha , Al-Shamali Adnan , Chanvin-Laaouissi Alice , Belgodere Clement , Liz Losada Ramiro , Al-Bannaw Osamah , Tertois Anne-Laure 
Published: November 2016

AbstractThe aim of this work is to validate the Geomechanical Fractures Attributes derived from a paleo-geochronological mathematical transformation as a tool to assess the areal repartition of natural tectonic fractures. A Fracture Probability (geomechanical attribute) model has been realized on the tight carbonates of the Najmah-Sargelu units (West Kuwait) and successfully validated against well fluid production data.
Prelude FLNG - Field Development Challenges
Authors: Van Nispen D. J. , Hodgson B. S. , Sims C. E. , Leong K. , Willyams I. 
Published: November 2016

Abstract
Development drilling in the Prelude field was successfully completed in 2015. The development plan included seven horizontal wells to deliver high reliability production to the Prelude FLNG facility. The Prelude FLNG development in Australia will be the first deployment of Shell's Floating LNG technology.
There were a number of challenges associated with the Prelude field development plan. These included drilling the first horizontal wells in the basin, the need to meet FLNG operating constraints, and management of reservoir uncertainty. The challenges needed to be considered in the context of a limited intervention strategy, hence the need to "get it right the first time".
Challenges were addressed in three project phases. Firstly by thorough field development planning in the Concept Selection phase of the project, leading to a development concept that was robust across a range of reservoir uncertainties and risks. Next was extensive contingency planning in the pre-drill phase to enable structured and timely decision making to manage a range of subsurface outcomes and operational events. Finally during the execution phase, drilling was separated into two seasons to allow learnings from season 1 to be incorporated into season 2. The success of this approach was enabled by a fully integrated multidisciplinary team of Subsurface and Well Engineering staff supported by global expertise from within the Shell group.
Statistical Uncertainty Analysis and Design Optimization of CO2 Trapping Mechanisms in Saline Aquifers
Authors: Temitope Ajayi , Sulemana Nuhu , Gomes Jorge S. , Oppong Riverson 
Published: November 2016

AbstractCO2 Storage as a technology is one that has been widely applied for the achievement of a greener world. It is considered as the only technology that mitigates global warming whilst, yet, allowing for the continuous use of fossil fuels which power our world today. Trapping efficiency of CO2 in saline aquifers depends on engineering design strategies and aquifer parameters. The range of plausible factors that could affect the efficiency creates the need for an optimization approach to reduce the risk and uncertainties associated with the process.This paper presents an uncertainty and optimization model for the residual and solubility trapping mechanisms in CO2 storage processes using the design of experiments and response surface methodology for representative aquifer models at field scale. Extensive numerical experiments were conducted using a commercial simulator and an optimum set of conditions was suggested for site based storage activities using the desirability concept. The factors for optimization in this study were broadly classified into aquifer and design parameters based on the controllability or non-controllability of selected factors. Aquifer parameters selected are the rock heterogeneity quantified using the Dykstra Parson coefficient, spatial continuity of properties estimated using the correlation lengths, temperature, mean permeability, anisotropy, residual gas saturation while the design parameters selected are the well type, injection strategy and completion intervals. These factors were selected based on literature search, intuitions and discussions. The aquifer model was kept constant for accurate analysis. The objective functions are the residual trapping coefficient (RTC) and the solubility trapping coefficient (STC).The process for the optimization technique utilized was a three pronged approach involving screening, characterizing and optimizing the parameters. Screening of parameters was performed using the factorial methods, the characterizing was performed using the Box Behnken response surface methodology while the optimization was performed using desirability functions.For results analysis, Pareto plots were constructed to show the effect of main factors and interaction factors on the objective functions, response surface plots were also made to show response effects. Results were validated with a commercial simulator. This study provides engineers with a better understanding of the most influential factors on trapping capacity during CO2 storage thus enabling them to make decisions with less risk and more certainty.