bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Short-Term and Long-Term Effects of Biofeedback-Assisted Relaxation Therapy in Patients With Heart Failure
Authors: Huang Tsuey-Yuan , Moser Debra K. , Hwang Shiow-Li 
Published: February 2017

Background Relaxation techniques can reduce sympathetic nervous system activation and stress, potentially improving heart failure patients’ physical and psychological outcomes. Purpose To examine the effects of biofeedback-assisted relaxation (BFAR) therapy in patients with heart failure. Methods A prospective randomized control study was conducted. Participants in the treatment group received BFAR therapy, while participants in the control group received standard of care. Short-term outcomes were physical symptoms and psychosocial variables measured at baseline and 3 months; long-term outcomes were cardiac events and mortality assessed at 12 months. Results Fifty-two heart failure patients participated in the study: 23 (mean age 60.0 ± 13.7 years; 60.9% male; 39.1% New York Heart Association III/IV) in the treatment group and 29 (mean age 59.2 ± 12.2 years; 72.4% male; 48.3% New York Heart Association III/IV) in the control group. Short-term effects of BFAR on outcome variables were not significantly different between treatment and control groups. However, longer event-free survival was found in the treatment group compared with the control group ( p = .019). Conclusions/Implications for Practices BFAR therapy is effective to improve cardiac event-free survival of heart failure patients and can be applied to clinical setting.
Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study
Authors: Mehta Parinda A. , Davies Stella M. , Leemhuis Thomas , Myers Kasiani , Kernan Nancy A. , Prockop Susan E. , Scaradavou Andromachi , O’Reilly Richard J. , Williams David A. , Lehmann Leslie , Guinan Eva , Margolis David , Baker K. Scott , Lane Adam , Boulad Farid 
Published: February 2017

Key Points
Alternative donor HCT can be performed in patients with FA without using radiation. All 26 patients younger than 10 years of age undergoing HCT for marrow failure using lower-dose busulfan-containing regimen survived.
Post-challenge insulin concentration is useful for differentiating between coronary artery disease and cardiac syndrome X in subjects without known diabetes mellitus
Authors: Liang Kae-Woei , Sheu Wayne H.-H. , Lee Wen-Jane , Lee Wen-Lieng , Pan Hung-Chih , Lee I.-Te , Wang Jun-Sing 
Published: February 2017

Abstract
Background
Cardiac syndrome X (CSX) is characterized by angina pectoris but with patent coronary arteries. Our previous study demonstrated that subjects with CSX had a higher fasting insulin-resistance (IR) than the controls. However, few studies have investigated the degree of IR, including oral glucose tolerance test (OGTT)-derived indices and profiles of metabolic abnormalities between CSX and coronary artery disease (CAD).

Methods
Ninety-two CSX and 145 CAD subjects without known diabetes mellitus (DM) underwent coronary angiogram (CAG) for angina pectoris and also agreed to receive OGTT and glycated hemoglobin (HbA1C) evaluations for screening abnormal glucose regulation and IR.

Results
CAD group had more subjects with metabolically unhealthy obesity (52.4 vs. 31.5%, p < 0.001) than the CSX group. The CAD group had higher OGTT 2 h glucose and insulin (both p < 0.005) while fasting glucose, insulin and HOMA-IR were similar to those of CSX subjects. In the binary regression analysis, OGTT 2 h insulin and being metabolic unhealthy were significantly different between the CAD and CSX groups, but there were no significant differences in Matsuda index, fasting glucose, insulin, HOMA-IR, or HbA1C.

Conclusions
Post challenge OGTT 2 h insulin and being metabolic unhealthy were useful parameters in differentiating between CAD and CSX in subjects without known DM but suffered from angina pectoris and underwent CAG. Different degrees of IR and metabolic abnormalities might be implicated in the pathogenesis of micro vs. macro vascular coronary diseases.
Trial registration NCT01198730 at https://clinicaltrials.gov, Registered Sep. 8, 2010
Towards a better understanding of the Ruppia maritima complex (Ruppiaceae): Notes on the correct application and typification of the names R. cirrhosa and R. spiralis
Authors: Ito Yu , Ohi-Toma Tetsuo , Nepi Chiara , Santangelo Annalisa , Stinca Adriano , Tanaka Norio , Murata Jin 
Published: February 2017

AbstractRuppia cirrhosa and R. maritima are two widely used names, each applied respectively to a long‐ and coiled‐pedunculate species or a short‐ and non‐coiled pedunculate species of Ruppia. The nomenclatural history of the two names is outlined here. A lectotype for the name R. cirrhosa is designated and the name is shown to be a homotypic synonym of R. maritima. Consequently, R. spiralis has nomenclatural priority over R. cirrhosa for the long‐ and coiled‐pedunculate Ruppia.
Cytogenetic insights into an oceanic island radiation: The dramatic evolution of pre‐existing traits in Cheirolophus (Asteraceae: Cardueae: Centaureinae)
Authors: Hidalgo Oriane , Vitales Daniel , Vallès Joan , Garnatje Teresa , Siljak-Yakovlev Sonja , Leitch Ilia J. , Pellicer Jaume 
Published: February 2017

AbstractThe genus Cheirolophus constitutes one of the most striking cases of species radiation in Macaronesia, where it diversified into a lineage of ca. 20 endemic species at a rate that is amongst the fastest reported for oceanic islands. Whilst the cytogenetic dynamics of many of the Macaronesian Cheirolophus species have been comparatively well studied, an overall vision of chromosome and genome evolution has been hampered by the lack of data for the earliest‐diverging species, Ch. crassifolius. In this study, we have completed the cytogenetic survey of Cheirolophus to investigate how different cytogenetic traits may have contributed to the dramatic radiation of the genus in Macaronesia. We provide new cytogenetic data (i.e., chromosome counts, genome size estimates and physical mapping of 35S rDNA loci) for several key species, including Ch. crassifolius, and then model trait evolution within a phylogenetic context. Our results reveal a trend of genome downsizing accompanied by a dramatic increase in number of 35S rDNA loci which started early in the evolutionary history of the genus, before its radiation in Macaronesia. It is notable that the increasing number of 35S rDNA loci has not been driven by polyploidisation, in contrast to the more typical trend observed in many angiosperms. In addition, the number of 35S rDNA loci was observed to negatively correlate with genome size, which is also very unusual in angiosperms. It is suggested that non‐homologous and unequal homologous recombination are the most likely mechanisms to explain these observations and we discuss whether the unique genomic architectures of Cheirolophus could have predisposed the genus to its successful and rapid speciation in Macaronesia.
Technology improvement of ultrasonic refinement of machinery work surfaces based on phenomenological investigation of cavity formations
Authors: Сундуков Сергей , Sundukov Sergey , Нигметзянов Равиль , Nigmetzyanov Ravil , Фатюхин Дмитрий , Fatyukhin Dmitriy 
Published: February 2017

The study of processes based on cavitation use required a clear definition of phenomena arising in liquid at high-frequency oscillation impact upon it. For the in-depth study of the phenomena under investigation in the given work there was used a high-speed video filming.
As the analysis of high-speed filming has shown after closing a bubble is divided into many pieces which, in their turn, pulse in-phase. At the same time there is observed a formation of complex bubble formations which are offered to be called clusters (Fig. 3).
Bubbles formed under the influence of variable acoustic pressure and located at a small distance from each other combine. Two processes take place simultaneously – bubbles combining (coalescence) and the integration of small bubbles in larger ones under the influence of cohesion forces with the formation of general structures (coagulation). The coalescence is followed with the transition of a system in a state with lower free energy.
Technology of residual stresses removal at multi-cycle racers running-in
Authors: Балаев Андрей , Balaev Andrey , Королев Альберт , Korolev Albert , Яковишин Александр , Yakovishin Aleksandr 
Published: February 2017

The substantiation of the new technology of multi-cycle racer running-in is shown. A technological method for racer resi-dual stresses removal by means of multi-cycle centerless running-in is described. For the computation of running-in basic time which is necessary for the complete removal of residual stresses there is developed a simulator. A simulator takes into account geometrical and mechanical conditions of the contact of rollers and a racer, physical-mechanical and geometrical parameters of a racer. On the basis of the simulator obtained there is carried out an investigation of the dependence of residual stress upon the duration of racer multi-cycle running-in for various stressed states. It is established that for the efficient stress removal the running-in time must be optimum. If time is lesser than optimum, then there is no a complete removal of residual stresses.
At processing time longer of optimum one after a complete removal of residual stresses the accumulation of new residual stresses takes place.
Risky Recombinations: Institutional Gatekeeping in the Innovation Process
Authors: Ferguson John-Paul , Carnabuci Gianluca 
Published: February 2017

Theories of innovation and technical change posit that inventions that combine knowledge across technology domains have greater impact than inventions drawn from a single domain. The evidence for this claim comes mostly from research on patented inventions and ignores failed patent applications. We draw on insights from research into institutional gatekeeping to theorize that, to be granted, patent applications that span technological domains must have higher quality than otherwise comparable, narrower applications. Using data on failed and successful patent applications, we estimate an integrated, two-stage model that accounts for this differential selection. We find that more domain-spanning patent applications are less likely to be approved, and that controlling for this differential selection reduces the estimated effect of knowledge recombination on innovative impact by about one-third. By conceptualizing the patent-approval process as a form of institutional gatekeeping, this paper highlights the institutional underpinnings of and constraints on the innovation process.The online appendix is available at https://doi.org/10.1287/orsc.2016.1106 .
ASPEK BIOLOGI IKAN PARI BLENTIK (Dasyatis cf. kuhlii) YANG TERTANGKAP DI LAUT JAWA
Authors: Dharmadi Dharmadi 
Published: February 2017

Penelitian dilakukan pada tahun 2002 sampai dengan 2003 di tempat pendaratan ikan Muara Angke dan Laboratorium Balai Riset Perikanan Laut Muara Baru, Jakarta. Data aspek biologi reproduksi ikan pari blentik (Dasyatis cf. kuhlii), berasal dari hasil tangkapan sampingan dari alat tangkap jaring dasar yang beroperasi di Laut Jawa dan didaratkan di tempat pendaratan ikan Muara Angke. Hasil penelitian menunjukkan ukuran lebar tubuh ikan pari blentik (Dasyatis cf. kuhlii) terkecil antara 170 sampai dengan 190 mm dan ukuran terbesar antara 330 sampai dengan 350 mm. Hubungan antara lebar cawan dan panjang klasper ikan pari blentik (Dasyatis cf. kuhlii) menunjukan hubungan yang linier (R2=0,7629). Kondisi klasper belum terjadi pengapuran atau sebagian mengandung zat kapur (non or partially calcified claspers) terdapat pada ukuran lebar tubuh <200 mm, sedangkan kondisi klasper penuh zat kapur (fully calcified claspers) terdapat pada ukuran lebar tubuh >250 mm. Ukuran embrio terkecil dijumpai pada bulan Januari yaitu antara 25 sampai dengan 30 mm dan terbesar antara 110 sampai dengan 115 pada bulan Agustus. Sebagian besar ikan pari blentik (Dasyatis cf. kuhlii) jantan yang tertangkap di Laut Jawa dalam kondisi matang kelamin. Berdasarkan pada uji X2, perbandingan kelamin jantan dan betina berbeda nyata (P<0,1). This study was conducted at Muara Angke fish landing site and Research Institute for Marine Fisheries Laboratory Muara Baru Jakarta on 2002 to 2003. Reproduction biology data of Dasyatis cf. kuhlii were taken from catched of bottom net fishing gear that operated in the Java Sea. The result showed that the smallest and the biggest of Dasyatis cf. kuhlii ranging from 170 to 190 mm and 330 to 350 mm disc width, respectively. Relationship between clasper length and disc width was linier (R2=0.7629). Condition of sex maturity stage of male was non or partially calcified claspers found at size <200 mm Wd, while fully calcified claspers was found at size >250 mm Wd. The smallest size embryo of ranging from 25 to 30 mm was found in January and the biggest ranging from 110 to 115 mm was found from in August. Most of Dasyatis cf. kuhlii caught in the Java Sea were mature. Sex ratio was significant different between male and female (X2 test, P<0.1).
Trastuzumab in Human Epidermal Growth Factor Receptor 2-Positive Early Breast Cancer: Results of a Prospective, Noninterventional Study on Routine Treatment Between 2006 and 2012 in Germany
Authors: Dall Peter , Koch Thorsten , Göhler Thomas , Selbach Johannes , Ammon Andreas , Eggert Jochen , Gazawi Nidal , Rezek Daniela , Wischnik Arthur , Hielscher Carsten , Keitel Stella , Cirrincione Ursula , Hinke Axel , Feisel-Schwickardi Gabriele 
Published: February 2017

AbstractPurposeTrastuzumab is part of the standard treatment in patients with human epidermal growth factor receptor 2-positive early breast cancer in addition to (neo)adjuvant chemotherapy. This German prospective noninterventional study, which included major patient cohorts underrepresented in the pivotal randomized studies, examined the generalizability of the results of those studies.Patients and MethodsBetween 2006 and 2012, 4,027 patients were enrolled and treated with trastuzumab; they were unselected regarding age or concomitant/sequential adjuvant chemotherapy. Long-term outcome data were obtained in yearly intervals. All analyses were descriptive in nature.ResultsAmong 3,940 evaluable patients, 26% were elderly (older than 65 years of age). More than half of the population had pN0 tumor stage. Ninety-four percent received chemotherapy: 78% as adjuvant treatment and 14% as neoadjuvant treatment, 2% both. Anthracyclines were administered in 87% and taxanes in 66%. Trastuzumab was stopped prematurely in 9% (because of cardiotoxicity in 3.5%). Recurrence-free survival was 90.0% (95% confidence interval [CI], 88.9%–91.1%) and 82.8% (95% CI, 81.2%–84.4%) after 3 and 5 years, respectively. The corresponding figures for overall survival were 96.8% (95% CI, 96.1%–97.6%) and 90.0% (95% CI, 88.6%–91.4%). Pathological primary tumor size, lymph node involvement, and hormone receptor status had the greatest independent effect on recurrence risk. Cardiac function toxicity of National Cancer Institute common toxicity criteria grade ≥2 and ≥3 was observed in 2.5% and less than 1% of patients, respectively.ConclusionThe maturing follow-up data seem to confirm the beneficial results of trastuzumab treatment for early breast cancer from the randomized studies. Moreover, these findings support use of trastuzumab-based therapy in patients groups less commonly included in the phase III trials (e.g., elderly patients and those with stage I disease).
Cancer and Venous Thromboembolic Disease: A Review
Authors: Donnellan Eoin , Khorana Alok A. 
Published: February 2017

Abstract
Venous thromboembolism (VTE), including deep-vein thrombosis and pulmonary embolism, represents a major cause of morbidity and mortality in cancer patients. Patients with cancer are six times more likely to develop VTE than their noncancer counterparts, and VTE is the second leading cause of death in cancer patients. Despite the publication of major consensus guidelines setting out recommendations for thromboprophylaxis in cancer patients, there remains a gulf between these guidelines and clinical practice. In general, thromboprophylaxis is recommended for most patients hospitalized with active cancer. Furthermore, outpatient thromboprophylaxis may be used in carefully selected high-risk ambulatory patients. Certain areas of controversy still remain. Although low-molecular-weight heparin has been shown to be superior to vitamin K antagonists in cancer patients, the role of direct oral anticoagulants is still uncertain. Moreover, recurrent thromboembolism, bleeding, and thrombocytopenia are frequently seen in cancer patients. Optimal anticoagulation in such instances presents a major challenge to clinicians. Modern computed tomography techniques have resulted in an increase in the detection of “incidental” VTE. Despite a growing body of evidence promulgating standard anticoagulant treatment in such cases, these cases present further challenges for members of the multidisciplinary team.
De las aulas universitariss a la toga: la trayectoria académica de los ministros del Supremo Tribunal Federal brasileño (1988-2013)
Authors: Rabelo Queiroz Rafael Mafei , Pommê Gama Barbara , Dos Santos Acca Thiago 
Published: February 2017

A través el estudio de las trayectorias académicas de los ministros de Supremo Tribunal Federal de Brasil y mediante la inclusión del requisito del “notorio saber jurídico”, impuesto por la Constitución de 1988 a todos los miembros de la corte, este artículo pretende desvelar patrones o criterios, hoy poco claros, de lo que en la práctica ha sido considerada una trayectoria de vida sobresaliente de los ministros elegidos, y su mayor o menor relación con el pasado académico de los magistrados. De tal forma se propone adentrarse en el interrogante sobre cómo los cambios en el mercado jurídico de las últimas décadas han impactado en la forma en que se han provisto los cargos de magistrados en este tribunal.
Message from Editor
Authors: Baskan Gulsun Atanur 
Published: February 2017

Dear Readers,It is the great honor for us to publish sixth volume, fourth issue of Contemporary Educational Researches Journal.Contemporary Educational Researches Journal welcomes original empirical investigations and comprehensive literature review articles focusing on educational issues. Contemporary Educational Researches Journal is an international peer-refereed journal that promotes the researches in the field of contemporary teaching and learning approaches and theories.The scope of the journal includes, but is not limited to; the following major topics as they relate to: Active Learning, Administration of Education, Adult Education, Affective Learning, Arts Teaching, Asynchronous Learning, Behaviorist Learning, Blended Learning, Chemistry Education, Classroom Assessment, Classroom Management, Classroom Teacher Education, Collaborative Learning, College and Higher Education, College and Higher Education, Constructivist Learning, Content Development, Distance Learning, E-administration, Simulation and Virtual Worlds, Guiding and Counseling, Healthy Education, High School Teacher Education, History Education, Instructional Design, Learners Diversity, Inclusiveness and Inequality, Learning and Teaching Research Methods, Learning Assessment and Evaluation, Learning Assessment and Evaluation, Learning Psychology, Lifelong Learning Strategies, Learning Skills, Vocational Education, Measurement and Evaluation in Education, New Learning Environments, Portfolio Assessment, Professional Development and School Administration.Impact of authentic context in teaching English, perceptions of children about the concept of pets, examination of humans and animals in terms of attachment theory, examining school variables and PISA math achievement results, co-authorship networks and institutional collaboration and mental lexicon and the selection of lexical nodes topics have been included into this issue. The topics of the next issue will be different. You can make sure that we will be trying to serve you with our journal with a rich knowledge in which different kinds of topics are discussed in 2016 Volume.A total number of seventeen (17) manuscripts were submitted for this issue and each paper has been subjected to double-blind peer review process by the reviewers specialized in the related field. At the end of the review process, a total number of six (6) high quality research papers were selected and accepted for publication.We present many thanks to all the contributors who helped us to publish this issue.Â Best regards,Prof. Dr. Gulsun Atanur BaskanEditor â€“ in Chief
Examining school variables affecting PISA 2012 math achievement in Turkey and Shanghai-China
Authors: Kale Mustafa 
Published: February 2017

The main purpose of the research is to examine school variables that have effect on Programme for International Student Assessment (PISA) 2012 math achievement in Turkey and Shanghai-China. The research was designed in casual comparison model. Research population was constituted by student in age group of 15 in Turkey and Shanghai-China in 2012.The sample consists of 4848 students and 170 schools in Turkey and 5177 students and 155 schools inÂ Shanghai-China that participated in PISA 2012. Two-leveled Hierarchical Linear Modelling (HLM) was used to analyze data because the data collected in PISA 2012 had a hierarchical data structure. As a result of analysis, variability in math scores, 63% in Turkey andÂ 47% in Shanghai-China, was found due to the difference between the mean math scores of schools. It was determined thatÂ MACTIV, SCMATEDU and TCMORALE in Turkey and MACTIV, in Shanghai-China statistically affect on math achievement.Â Keywords: PISA, school administration, school variables, HLM