bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Fate of Bone Graft for Periprosthetic Osteolysis in Total Ankle Arthroplasty
Authors: Park Yoo Jung , Shim Dong-Woo , Hwang Yeokgu , Lee Jin Woo 
Published: September 2017

Category: Ankle Arthritis Introduction/Purpose: Periprosthetic osteolysis in total ankle arthroplasty (TAA) is a substantial problem. It may cause implant failure and has potential to affect long-term implant survival. To prevent major revisional arthroplasty, it is important to make an early diagnosis of osteolysis and decide an appropriate timing of surgical intervention such as bone graft. We report our experience of bone graft for osteolysis after TAA associated with clinical and radiologic outcome. Methods: Between May 2004 and Oct. 2013, 238 primary TAA were performed on 219 patients. We excluded 37 ankles with follow-up less than 24 months; thus, 201 ankles in 185 patients with mean follow-up of 61.9 (range, 24-130) months were included in the study. Nineteen patients were treated with a total of 21 bone graft procedures for periprosthetic osteolysis after TAA. Of these patients, 12 (57.1%) were males with mean follow-up length after bone graft 35.0 months. Location of osteolysis, bone grafting method and clinical outcome parameters using visual analog scale (VAS), American Orthopaedic Foot and Ankle Society (AOFAS) score were recorded. Results: Radiographs revealed total of 62 osteolysis lesions in 19 patients; 35 (56.5%) distal tibial lesions, 23 (37.0%) talar lesions. Autogenous iliac bone graft was used in 18 procedures (85.7%). The mean scores (and standard deviation) improved for the VAS from 4.8 ± 1.23 points before bone graft to 3.0 ± 0.94 points at the last follow-up (p<0.05); and for the AOFAS score from 76.8 ± 5.9 before bone graft to 84.3 ± 4.5 at the last follow-up (p<0.05). After 21 bone graft procedures, 6 demonstrated detection of newly developed osteolysis. One patient needed a repeat bone graft procedure with cementation after the primary bone grafting due to large cyst on distal tibia. There was no implant failure or major revisions after the bone graft. Conclusion: Bone graft for periprosthetic osteolysis may improve patient’s clinical outcome and give support to the structures surrounding the implant. Bone grafting in optimal timing may also improve implant survivorship. However, further study is needed for the etiology of newly developed painless osteolysis even after the bone graft.
Chronic Deltoid Ligament Insufficiency Repair with Internal Brace™ Augmentation
Authors: Pellegrini Manuel , Carcuro Giovanni , Cuchacovic Natalio , Somarriva Marcelo , Heldt Mario Escudero , Torres Nicolas , Birman Eddie , Muñoz Gerardo 
Published: September 2017

Category: Ankle, Arthroscopy, Sports Introduction/Purpose: Patients with chronic deltoid ligament insufficiency (CDLI) present a challenging situation in foot and ankle surgery. Although numerous surgical procedures have been described, optimal treatment is still a matter of debate. While the treatment armamentarium ranges from simple ligament repair to complex deltoid reconstructions with or without realignment osteotomies, direct repair augmented with an Internal Brace™ (Arthrex, Inc., Naples FL, USA) device appears to be an attractive intermediate option. We investigated functional outcomes and complications in patients with CDLI operated on using Internal Brace™ augmentation. Methods: After IRB approval, a prospective study was conducted. Patients were included if they were older than 18 years, presented medial ankle pain and/or giving way, exhibited asymmetric flexible hindfoot valgus, failed conservative treatment, and had a positive MRI evaluated by an independent radiologist. Patients with less than six months of follow-up, stage IV flatfoot deformity, neuropathy and/or inflammatory arthritis were excluded from the study. CDLI diagnosis was confirmed intraoperatively with the arthroscopic ankle drive-through sign. Patients were evaluated preoperatively and postoperatively using foot and ankle ability measure (FAAM) score, 36-item short form survey (SF-36), and grade of satisfaction. Paired t-tests were used to assess the pre- and postoperative FAAM and SF-36 scores. Results: Eleven patients met inclusion criteria. Nine patients were male and two female, with a mean age of 32 (18-61). Six ankles were right and five left. 88% presented with medial ankle pain, 67% medial drawer, 88% asymmetric hindfoot valgus, and 44% multidirectional ankle instability. No patient was lost to follow-up, with a mean follow-up time of 13.5 months (6-21). Preoperative FAAM and SF-36 scores improved from 58.7 to 75.3 and from 60.2 to 84.4 postoperatively, respectively (p<0.05). Two implant failures were observed, with no apparent compromise of construct stability. No patient was re-operated. Conclusion: Our results suggest that deltoid ligament repair with Internal Brace™ augmentation in patients with CDLI is a reliable option with good functional outcomes and high satisfaction grade in short term follow-up.
Deformity and Clinical Outcomes Following Surgical Correction of Charcot Foot
Authors: Pinzur Michael , Schiff Adam 
Published: September 2017

Category: Diabetes Introduction/Purpose: There is growing acceptance that the historic accommodative treatment of the acquired deformity associated with Charcot Foot arthropathy leads to very poor patient reported outcomes. Surgical correction of the acquired deformity is now advised with the goals of improving ambulation and quality of life. Methods: Over a twelve-year period, 214 consecutive patients (9 bilateral) underwent surgi-cal reconstruction of the acquired deformity associated with symptomatic midtarsal dia-betes- associated Charcot Foot arthropathy. The patterns of midtarsal deformity were ar-bitrarily stratified into three clinical groups based on observed weight bearing pattern, radiographic relationship of the forefoot to the hindfoot and integrity of the talo-calcaneal joint. All patients were followed for a minimum of one year. All had weight bearing radiographs before surgery and at a minimum of one year following surgery. A VALGUS deformity pattern was present in 138, VARUS in 48 and DISLOCATION of the talo-calcaneal joint in 37. Surgery included tendon-Achilles lengthening and an attempt at bony correction of the non-plantigrade clinical deformity. Immobilization in all cases was accomplished with a three level static circular external fixator. Clinical outcomes were based on suc-cessfu1 resolution of infection and the ability to resume independent walking with com-mercially-available therapeutic footwear. Results: Seven patients died within a year of surgery. Overall, 173 of 216 feet (80.1%) achieved a favorable clinical outcome rating. The VALGUS deformity pattern was the most common, with 120 of 138 patients (89.6%) achieving a favorable clinical outcome rating. There were two transtibial and one transmetatarsal amputations in this group. Twenty-seven of the 48 patients (58.7%) with a VARUS deformity pattern achieved a favorable clinical outcome rating, with seven undergoing transtibial, one Syme’s and one transmetatarsal amputation. There were thirty- seven patients with a valgus deformity pattern characterized by loss of integrity, i.e. DISLOCATION, of the talo-calcaneal joint. Correction of deformity and a favorable clinical outcome rating was achieved in twenty-six (72.2%), with one knee disarticulation and two transtibial amputations. Conclusion: Overall, 176 of 223 (77.6%) patients, many with severe structural deformity and osteomyelitis, achieved a favorable clinical outcome. Patients with a VARUS deformity pattern, or loss of integrity of the talocalcaneal joint, were less likely to achieve a favora-ble clinical outcome rating. This retrospective case series suggests a reasonably good probability of improving clinical outcomes in this complex patient population. This de-formity stratification should be helpful going forward when counseling patients with non-plantigrade diabetes- associated Charcot Foot deformity on the risk-benefit ratio associat-ed with surgical correction of their acquired deformity.
Matrix-Associated Stem Cell Transplantation (MAST) in Chondral Defects of the Ankle is Safe and Effective - 5-Year-Followup
Authors: Richter Martinus , Meissner Stefan , Zech Stefan 
Published: September 2017

Category: Ankle, Arthroscopy, Sports Introduction/Purpose: The aim of the study was to assess the 5-year-follow-up of matrix-associated stem cell transplantation (MAST) in chondral defects of the ankle. Methods: In a prospective consecutive non-controlled clinical follow-up study, all patients with chondral defect that were treated with MAST from April1 2009 to September 30, 2011 were analyzed. Size and location of the chondral defects and the Visual- Analogue-Scale Foot and Ankle (VAS FA) before treatment and at follow-up were analysed. Stem cell-rich blood was harvested during the procedure from the ipsilateral pelvic bone marrow with a Jamshidi needle (10 x 3 mm, Cardinal, Dublin, OH, USA) and a special syringe (Arthrex-ACP, Arthrex, Naples, FL, USA) through a stab incision. The syringe was centrifuged (10 minutes, 1,500 rotations per minute). The supernatant was used to impregnate a collagen I/III matrix (Chondro-Gide, Geistlich, Wollhusen, Switzerland) that was cut to the size of the cartilage defect roughly before and definitely after. The matrix with stem cells was fixed into the chondral defect with fibrin glue (Tissucoll, Deerfield, IL, USA). Results: Sixty-six patients with 69 chondral defects were included in the study. The age of the patients was 35 years on average (range, 12-64 years). VAS FA before surgery was 48.9 on average (range, 16.5-75.9). The defects were located as follows, medial talar shoulder, n=28; lateral talar shoulder, n=28 (medial and lateral talar shoulder, n=3), tibia, n=3. The defect size was 1.4 cm2 on average (range, .6 - 6 cm2). 60 patients (91%) completed 5-year-follow-up. No patient was converted to fusion or total ankle replacement. The VAS FA improved to an average of 78.2 (range, 60.8-100; p=.01). Conclusion: MAST led to improved and high validated outcome scores at 5-year-followup. No method related complications were registered. Even though a control group is missing, we conclude that MAST is an effective method mid-term for the treatment of chondral defects of the ankle.
Primary Results of Bone Biopsies in Outpatients with Neuropathic Ulcers
Authors: Vris Alexandros , Massa Edward , Ahluwalia Raju , Kavarthapu Venu 
Published: September 2017

Category: Diabetes Introduction/Purpose: Patients with Charcot foot disease often develop ulcers that probe to bone due to progressive deformity and loss of protective sensation. Infection of the ulcers and the underlying bone is common. In order to diagnose and treat osteomyelitis, especially in cases where reconstruction is planned, the pathogen must be isolated. The need for bone debridement and the duration of antibiotic treatment depends on the presence of bone infection. Percutaneous bone biopsies through intact skin is the gold standard for acquisition of samples for cultures. The presence of neuropathy negates the need for anaesthesia and renders biopsies possible in the outpatient setting. In our study we compare the results of bone biopsies with wound swabs and document the safety of the technique in clinic. Methods: Thirty five patients were included in the study. Inclusion criteria were the presence of neuropathy and foot ulcers with exposed bone (Grade 3 University of Texas wound classification). Samples were obtained by three different doctors with aseptic technique through intact skin and sent for cultures. The area of the bone where the sample was taken from was defined by the location of the ulcer, the available imaging and anatomical landmarks. Complications such as bleeding and entry point infection and delayed healing were documented. Superficial ulcer swabs were also obtained for comparison. Results: In 37 patients 2 procedures were abandoned due to pain; otherwise no complications during or after the biopsy were recorded and the procedure duration was 4 minutes at most. There was bacterial growth in 40% of bone biopsy samples, compared to 65.7% of superficial swabs. Cultures were polymicrobial in 35.7% of positive biopsies and 82.6% of positive ulcer swabs. Concordance between bone biopsy and swab results was seen in 16/35 (45.7%) of samples. In 7 patients both tests were negative and in 9 both positive. 7/9 of samples that were positive with both methods grew the same organism. Conclusion: Our study showed that there is poor concordance of the results of the two tests. Wound swabs have high rates of polymicrobial cultures; in comparision bone biopsies are more reliable in confirming a specific microbial organism and dictating the need for and type of antibiotic. Targeted antibiotics can thus be safely used, potentially reducing the complications and the cost of broad-spectrum antibiotic treatment. The technique of needle bone biopsy is easy, safe and reproducible, and pain is not a limiting factor for in outpatients with neuropathy.
Ligament Balancing During TAR in Varus Deformity by Open Wedge Osteotomy of the Medial Malleolus
Authors: Wagener Joe , Schweizer Christine , Zwicky Lukas , Hintermann Beat 
Published: September 2017

Category: Ankle Arthritis Introduction/Purpose: After reducing the tilted talus during total ankle replacement (TAR) in severe varus deformities, the surgeon is faced to a contract medial joint and an abducted medial malleolus leaving a wide gutter. A sliding osteotomy will release the deltoid ligament but the “horizontal” position of the medial malleolus remains and bony containment of the ankle joint is not restored. We propose an open wedge osteotomy, which will both lengthen and adduct the medial malleolus and restore ligament balancing. Fixation is done by either screw or plate fixation. We present our primary results with this new technique. Methods: From 2008-2015 Total Ankle Replacement combined with open wedge medial malleolar osteotomy was done in 50 ankles (48 patients). Inclusion criteria: Takakura stages 3 and 4 ankle arthritis. Minimum follow-up was defined as one year. Results: Neutral alignment was achieved in all ankles at last follow-up. AOFAS score increased from 36 preoperative to 82 at last follow-up. In 15 Ankles an additional bony procedure was done during the TAR surgery (Calcaneus Osteotomy: 5, Dorsiflexion Osteotomy of first ray: 6, Fibula Osteotomy: 4, peritalar fusion: 4) Complications included one non-union of the medial malleolus, which resolved after revision. One deep infection that was treated in a staged procedure with reimplantation of a TAR and no recurrence of infection. Two luxations of the polyethylene due to insufficient lateral ligaments and syndesmotic dehiscence, both were stable at final follow-up after revision (ligament reconstruction and tight-rope Fixation). Conclusion: Open wedge osteotomy of the medial malleolus restores the bony containment of the ankle joint and decreases the tension of the deltoid ligament. It is a valuable tool for ligament balancing during TAR.
Peroneal Tendon Tears
Authors: Wagner Emilio , Wagner Pablo , de Solminihac Diego Zanolli , Ortiz Cristian , Díaz Andres Keller , Radkievich Ruben , Palma Felipe , Guzman-Venegas Rodrigo 
Published: September 2017

Category: Ankle, Basic Sciences/Biologics, Sports Introduction/Purpose: Peroneus brevis tendon tears are frequently diagnosed when ankle instability is present. No clear guideline exists as to when to repair or resect peroneal tendon tears, as most of the available literature uses Meyer’s work published in 1924 where a risk of spontaneous rupture would exist when less than 50% of the tendon remains undamaged. Our objective was to analyze the mechanical behavior of cadaveric peroneal tendons subjected to an artificially made damage, compromising 66% of its visible width and tested in a cyclic and failure phase. Our hypothesis was that no failure would be observed in the cyclic phase. Methods: 8 cadaveric foot- ankle – distal tibia specimens were included in this study. A longitudinal full thickness tendon defect was created, 3 cms in length, centered behind the tip of the fibula, compromising 66% of the visible width of the peroneal tendons as measured by a caliper. The peroneal retinaculum was kept intact. All specimens were mounted onto a special frame specifically designed for the study. All tendons were tested in a cyclic fashion using 100 repetitions between 50 N and 200 N. If no visual change or tendon failure was observed after the initial testing, a load to failure test was performed until tendon rupture or fixation failure was observed. Tendon stiffness and load to failure were registered. Statistical analysis was performed using the SPSS software. Results: No tendon failed during the cyclic testing. No defect lengthening was observed after the cyclic phase. On the failure phase, the mean load resisted by the peroneus brevis was 416 N, with a 95% confidence interval between 351 N -481 N. The mean load resisted by the peroneus longus was 723 N, with a 95% confidence interval between 578 N – 868 N. All failures were at the level of the defect created. The coefficient of variation was low for both tendons. Conclusion: A 33% of remaining peroneal tendon was able to resist very high tensile forces; therefore, it can be suggested that a 66% defect can be repaired and does not necessarily need a tenodesis as it has been historically recommended. The high resistance offered by the peroneus longus tendon offers the theoretical potential to use part of it as a free graft to repair peroneus brevis tears. The 50% rule, which determines when a peroneal tendon tear needs a tenodesis or repair, should be revisited.
Peri-talar Osteotomy as Part of Treatment of Talar Osteochondral Defect of Varus Ankle
Authors: Wang Bibo 
Published: September 2017

Category: Ankle Introduction/Purpose: The etiology of osteochondral defect (OCD) of talus is not fully understood. Besides trauma, malalignment of ankle or hindfoot may play a role in the development of OCD. The aim of this study is to assess the efficacy of peri-talar osteotomy in addition to routine treatment of OCD of talus. Methods: This is a retrospective study of 52 cases of varus talar OCD during the period of 2009.9 to 2014.12. Micro-fracture or autograft transplantation were applied for the OCD first according to the dimension of the lesion in all cases. Then peri-talar osteotomy were performed to correct ankle or hindfoot mal-alignment in 26 cases according to the position of varus deformity, including 18 supramalleolar osteotomy, 6 calcaneal osteotomy and 2 combined distal tibial and calcaneal double osteotomy. Pre- and post-operative radiographic parameters of TAS, TTS, TLS angles and MoA were measured on mortise view, lateral view and hindfoot alignment view respectively. AOFAS-AH score, VAS score and SF36 score were performed to assess both subjective and objective outcome. Results: For the osteotomy group, there were statistically changes (P < 0.05) radiographically (TAS, TTS, MoA, TLS) after surgery. While the radiographic parameters didn’t change in the group without corrective osteotomy. AOFAS-AH score and VAS score increased significantly (P < 0.05) in both the osteotomy group and the non-osteotomy group. The SF36 scores score increased significantly (P < 0.05) in the osteotomy group while not significant in the non-osteotomy group. The AOFAS-AH and SF36 scores were statistically higher in the osteotomy group after surgery (p<0.05), and the VAS score were not statistically different in two groups. There were 5 out of 26 revised cases in the non-osteotomy group while 2 out of 26 revised cases in the osteotomy group. Conclusion: Peri-talar osteotomy in addition to routine treatment of OCD of talus results in better radiographic and functional outcome and lower recurrence for patients of varus talar osteochondral defect. Mechanical malalignment may contribute to progression of OCD of talus and thus should be corrected simultaneously.
Effects of age and gender on gait characteristics using a wearable foot inertial-sensor device assessment
Authors: Angthong Chayanin 
Published: September 2017

Category: Gait studies Introduction/Purpose: This study is to determine the effects of age and gender on the gait characteristics using a wearable foot inertial-sensor assessment in the patients with foot and ankle conditions. Methods: There were 53 patients with foot and ankle-related conditions (38 females and 15 males, mean age: 51.4 (±14.0) years) who were collected for this study. For all patients, the clinical assessments, including the evaluations with validated patient- reported outcome using visual analogue scale foot and ankle (VAS-FA) score and health-related quality of life using validated Short Form-36 (SF-36), diagnoses, and gait characteristics assessment using a wearable foot device with the Micro electro mechanical systems (MEMS) inertial-sensor technology during patients’ walking trial for a distance of 10-meter at their self-selected speed. This device captures the gait parameters as distance walked, step counts or length, cadence, and walking speed. Foot Pod output can be wireless synced to a compatible smartphone or tablet. Pearson’s correlation coefficient r or Analysis of variance (ANOVA) tests were used to express the correlation between age and gait parameters or to compare the parameters between male and female groups. Results: There were insignificantly negative Pearson’s correlation coefficients r between age and walking speed or between age and cadence (P>0.05). Male patients had significantly higher maximum walking speed (P=0.015) and step length than female patients (P=0.011). Conclusion: In contrary to the previous study, the present study demonstrated that higher age had no effect on the reduction of walking speed. However, the effects of gender on gait characteristics were proved as higher maximum walking speed and step length in men.