bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Group-based Assessment Approach in Nursing Education: The Perspective of Nursing Students on Group-based Assessment Process at a Namibian University
Authors: Nuuyoma Vistolina 
Published: May 2017

Group-based assessments used in the Bachelor of Nursing Science (clinical) Honours programme at a public university in Namibia are usually in the form of assignments and projects. Completing tasks in groups helps students to develop important skills like critical thinking and debating. In addition, it prepares them to work in the health-care environment where collaboration with others is required. That said, nursing students lack cooperation during the process of completing their group assignments or projects. A classroom-based research was conducted using action research as the design. The objectives were to: explore what is causing lack of cooperation during group-based assessment as perceived by nursing students, and to propose, implement and evaluate measures to improve cooperation during group-based assessment task completion. Themes that emerged as factors contributing to a lack of cooperation are: student motivation, student personal characteristics, lack of planning to approach the allocated task, student learning approaches, communication-related issues, and group composition and allocation procedures. The proposed measures of students to ensure cooperation are: selection of group leaders, determining lecturer roles in facilitating group assessment, improving communication, and involvement of students in the allocation procedures of group members.All suggestions were successfully implemented. Evaluation of measures to ensure cooperation revealed that students appreciated the group-based approach strategy given its very positive impact on their learning.
De herziene Aandeelhoudersrechtenrichtlijn: een eerste reflectie
Authors: Dijkhuizen T.C.A. , Nijland J. 
Published: May 2017

De herziene Aandeelhoudersrechtenrichtlijn: een eerste reflectie
In deze bijdrage reflecteren de auteurs op twee kernonderwerpen van de herziene Aandeelhoudersrechtenrichtlijn, namelijk aandeelhoudersbetrokkenheid en say on pay. Zij vragen zich af of de transparantieverplichtingen daadwerkelijk leiden tot een grotere aandeelhoudersbetrokkenheid. De introductie van een say on pay in Nederland lijkt de werking van artikel 2:135 BW te ondergraven.
Het verzetrecht van artikel 2:404 BW
Authors: Notenboom K. 
Published: May 2017

Het verzetrecht van artikel 2:404 BW
In het recente arrest inzake SNS/Propertize kwam het verzetrecht tegen het voornemen van de moedermaatschappij om de overblijvende aansprakelijkheid uit hoofde van een 403-verklaring te beëindigen aan de orde. In deze bijdrage bespreekt de auteur enkele knelpunten ten aanzien van het verzetrecht van artikel 2:404 BW: de verzetgerechtigdheid, de betwiste vorderingen en de omvang van de zekerheid of andere waarborg.
Differentiation of natural populations of the Scots pine (Pinus sylvestris L.) in Ukrainian Polissya based on the findings of research into the morphological markers of cones and seeds
Authors: Mazhula Olga , Fuchylo Yaroslav , Gordiyaschenko Alyona 
Published: May 2017

Research into variability of morphological markers of the reproductive organs in nine natural populations of the Scots pine of Ukrainian Polissya (Volyn, Rivne, Zhytomyr, and Kyiv regions) was carried out during which the colour of cones, seeds, winged seeds, and the apophysis of the cones of the trees of native populations of the Scots pine were examined.
The quantity and percentage of different morphological forms of the cone and seeds of the trees of investigated populations were defined. Trees with hooked (f. reflexa) apophysis of the cone (turning upwards) were discovered. As shown in the results of investigations, natural populations of the Scots pine of Ukrainian Polissya are characterized by a large variability of morphological forms. Altogether, 17 new forms of apophysis were described.
Cluster analysis of a complex of morphological markers was conducted. It showed differentiation of some populations from the Rivne region.
Ouvrir les portes de la prison : plaidoyer en faveur de la psychoéducation en milieu carcéral
Authors: Arseneault Catherine , Plourde Chantal , Marcotte Julie , Alain Marc , Bédard-Nadeau Marie-Eve 
Published: May 2017

Cet article vise à situer et à promouvoir la place de l’intervention psychoéducative auprès des personnes adultes délinquantes et criminalisées prises en charge par les systèmes correctionnels québécois et canadien. Malgré la diversité des milieux dans lesquels oeuvrent les psychoéducateurs, leur présence au sein des milieux carcéraux fait encore figure d’exception. Les données les plus récentes obtenues montrent qu’uniquement 0,36 % des psychoéducateurs membres de l’Ordre des psychoéducateurs et psychoéducatrices du Québec oeuvrent dans ces milieux. Cet article présente d’abord un examen des particularités du milieu carcéral, les deux principales philosophies d’intervention correctionnelle ainsi que certaines notions historiques essentielles à la compréhension des pratiques en milieu carcéral. Les meilleures pratiques visant la réduction de la récidive, objectif ultime de toutes interventions correctionnelles, seront ensuite dépeintes. L’intervention en milieu carcéral comportant plusieurs défis, notamment en raison du contexte contraignant d’intervention, certains enjeux qui guettent les psychoéducateurs désirant oeuvrer auprès de cette clientèle seront présentés. Tout au long de l’article, les liens entre l’intervention correctionnelle et l’intervention psychoéducative ayant pu être tracés par l’examen des milieux carcéraux sont présentés sous forme de sept différentes pièces à conviction. Ces pièces à conviction représentent des arguments qui soutiennent le plaidoyer, notre plaidoyer : notre souhait que les psychoéducateurs innovent pour que la psychoéducation soit présente dans les milieux carcéraux et ainsi que ces milieux bénéficient de l’expertise psychoéducative.
Évaluation de la trousse d’intervention A pour Autre©
Authors: St-Laurent Daphnée , Poulin Marie-Hélène 
Published: May 2017

Cet article porte sur les résultats obtenus dans le cadre de l’évaluation de la trousse d’intervention A pour Autre©. Il s’agit d’une trousse pédagogique composée de trois outils (guide, DVD, plateforme web interactive) élaborée pour soutenir l’apprentissage des habiletés sociales chez les jeunes présentant un trouble du spectre de l’autisme (TSA) âgés entre 6 et 17 ans. Elle s’adresse aux personnes autistes ainsi qu’à leurs parents et leurs intervenants. Une enquête par questionnaire en ligne et par la poste a été menée entre mars 2015 et février 2016 dans le but d’établir un portrait des utilisateurs ainsi que d’évaluer leur appréciation des divers éléments de la trousse. Cent cinq personnes (N = 105) ont répondu au questionnaire et vingt-huit (n =28) utilisent les outils. De façon globale, elles sont satisfaites de leur expérience (ergonomie du site web et utilité des outils) et considèrent la trousse efficace pour l’enseignement des habiletés sociales. Les répondants souhaitent que d’autres vidéos abordant des thèmes différents soient offertes.
Vision de chercheur, de clinicien ou de forcené de l’autisme? Laurent Mottron crée sa méthode ICI
Authors: Giroux Normand 
Published: May 2017

Une première partie de cet article recense le livre récent de Laurent Mottron,L’intervention précoce pour enfants autistes. L’idée porteuse de ce livre est que l’intelligence des autistes les sauve et que l’aide apportée en bas-âge doit se limiter à favoriser l’éclosion de cette intelligence et son déploiement. La recension constate qu’il s’agit non de science, mais de pseudo-science. Une seconde partie de l’article rétablit la bonne perspective : l’autisme est un dérèglement du psychique à géométrie variable qui appelle une intervention directe, formelle, explicite, transformatrice. L’analyse appliquée du comportement demeure la meilleure source pour cette intervention précoce.
Interactions of 172 plant extracts with human organic anion transporter 1 (SLC22A6) and 3 (SLC22A8): a study on herb-drug interactions
Authors: Lu Hang , Lu Zhiqiang , Li Xue , Li Gentao , Qiao Yilin , Borris Robert P. , Zhang Youcai 
Published: May 2017

BackgroundHerb-drug interactions (HDIs) resulting from concomitant use of herbal products with clinical drugs may cause adverse reactions. Organic anion transporter 1 (OAT1) and 3 (OAT3) are highly expressed in the kidney and play a key role in the renal elimination of substrate drugs. So far, little is known about the herbal extracts that could modulate OAT1 and OAT3 activities.MethodsHEK293 cells stably expressing human OAT1 (HEK-OAT1) and OAT3 (HEK-OAT3) were established and characterized. One hundred seventy-two extracts from 37 medicinal and economic plants were prepared. An initial concentration of 5 µg/ml for each extract was used to evaluate their effects on 6-carboxylfluorescein (6-CF) uptake in HEK-OAT1 and HEK-OAT3 cells. Concentration-dependent inhibition studies were conducted for those extracts with more than 50% inhibition to OAT1 and OAT3. The extract ofJuncus effusus, a well-known traditional Chinese medicine, was assessed for its effect on thein vivopharmacokinetic parameters of furosemide, a diuretic drug which is a known substrate of both OAT1 and OAT3.ResultsMore than 30% of the plant extracts at the concentration of 5 µg/ml showed strong inhibitory effect on the 6-CF uptake mediated by OAT1 (61 extracts) and OAT3 (55 extracts). Among them, three extracts for OAT1 and fourteen extracts for OAT3 were identified as strong inhibitors with IC50values being <5 µg/ml.Juncus effususshowed a strong inhibition to OAT3in vitro, and markedly altered thein vivopharmacokinetic parameters of furosemide in rats.ConclusionThe present study identified the potential interactions of medicinal and economic plants with human OAT1 and OAT3, which is helpful to predict and to avoid potential OAT1- and OAT3-mediated HDIs.
Differentiation ofBifidobacterium longumsubspecieslongumandinfantisby quantitative PCR using functional gene targets
Authors: Lawley Blair , Munro Karen , Hughes Alan , Hodgkinson Alison J. , Prosser Colin G. , Lowry Dianne , Zhou Shao J. , Makrides Maria , Gibson Robert A. , Lay Christophe , Chew Charmaine , Lee Pheng Soon , Wong Khai Hong , Tannock Gerald W. 
Published: May 2017

BackgroundMembers of the genusBifidobacteriumare abundant in the feces of babies during the exclusively-milk-diet period of life.Bifidobacterium longumis reported to be a common member of the infant fecal microbiota. However,B. longumis composed of three subspecies, two of which are represented in the bowel microbiota (B. longumsubsp.longum;B. longumsubsp.infantis).B. longumsubspecies are not differentiated in many studies, so that their prevalence and relative abundances are not accurately known. This may largely be due to difficulty in assigning subspecies identity using DNA sequences of16S rRNAortufgenes that are commonly used in bacterial taxonomy.MethodsWe developed a qPCR method targeting the sialidase gene (subsp.infantis) and sugar kinase gene (subsp.longum) to differentiate the subspecies using specific primers and probes. Specificity of the primers/probes was tested byin silico,pangenomic search, and using DNA from standard cultures of bifidobacterial species. The utility of the method was further examined using DNA from feces that had been collected from infants inhabiting various geographical regions.ResultsA pangenomic search of the NCBI genomic database showed that the PCR primers/probes targeted only the respective genes of the two subspecies. The primers/probes showed total specificity when tested against DNA extracted from the gold standard strains (type cultures) of bifidobacterial species detected in infant feces. Use of the qPCR method with DNA extracted from the feces of infants of different ages, delivery method and nutrition, showed that subsp.infantiswas detectable (0–32.4% prevalence) in the feces of Australian (n = 90), South-East Asian (n = 24), and Chinese babies (n = 91), but in all cases at low abundance (<0.01–4.6%) compared to subsp.longum(0.1–33.7% abundance; 21.4–100% prevalence).DiscussionOur qPCR method differentiatesB. longumsubspecieslongumandinfantisusing characteristic functional genes. It can be used as an identification aid for isolates of bifidobacteria, as well as in determining prevalence and abundance of the subspecies in feces. The method should thus be useful in ecological studies of the infant gut microbiota during early life where an understanding of the ecology of bifidobacterial species may be important in developing interventions to promote infant health.
On the use of a snow aridity index to predict remotely sensed forest productivity in the presence of bark beetle disturbance
Authors: Knowles John F. , Lestak Leanne R. , Molotch Noah P. 
Published: May 2017

AbstractWe used multiple sources of remotely sensed and ground based information to evaluate the spatiotemporal variability of snowpack accumulation, potential evapotranspiration (PET), and Normalized Difference Vegetation Index (NDVI) throughout the Southern Rocky Mountain ecoregion, USA. Relationships between these variables were used to establish baseline values of expected forest productivity given water and energy inputs. Although both the snow water equivalent (SWE) and a snow aridity index (SAI), which used SWE to normalize PET, were significant predictors of the long‐term (1989–2012) NDVI, SAI explained 11% more NDVI variability than SWE. Deviations from these relationships were subsequently explored in the context of widespread forest mortality due to bark beetles. Over the entire study area, NDVI was lower per unit SAI in beetle‐disturbed compared to undisturbed areas during snow‐related drought; however, both SAI and NDVI were spatially heterogeneous within this domain. As a result, we selected three focus areas inside the larger study area within which to isolate the relative impacts of SAI and disturbance on NDVI using multivariate linear regression. These models explained 66%–85% of the NDVI and further suggested that both SAI and disturbance effects were significant, although the disturbance effect was generally greater. These results establish the utility of SAI as a measure of moisture limitation in snow‐dominated systems and demonstrate a reduction in forest productivity due to bark beetle disturbance that is particularly evident during drought conditions resultant from low snow accumulation during the winter.
Possible precursory signals in damage zone foreshocks
Authors: Savage Heather M. , Keranen Katie M. , P. Schaff David , Dieck Caitlin 
Published: May 2017

AbstractForeshocks may provide a precursory signal of an impending earthquake, but their role in nucleation of the main shock is unclear. One way to further our understanding of foreshock failure mechanisms is to determine where they occur in the fault zone. However, earthquake locations commonly include uncertainties large enough to allow rupture on either the main fault interface or on subsidiary fractures within a surrounding damage zone. Here we obtain precise earthquake locations, with ~10 m uncertainty, for foreshocks and aftershocks of an Mw 5.0 near Prague, OK, USA. Repeating earthquakes imply that some precursory slow slip occurred before the main shock. In addition, we show that foreshocks initially rupture faults and fractures throughout the 300 m thick fault damage zone and later localize onto a narrower zone (<100 m thick) nearer the main shock hypocenter. Focal mechanisms corroborate that foreshocks occur in the surrounding damage zone as well as on the main shock rupture interface. These results highlight that earthquake nucleation is most likely a complex feedback between frictional failure processes on the fault interface and deformation in the surrounding damaged rock, rather than simply nucleation on a single surface.
Predictors of Hospitalization, Length of Stay, and Cost of Care Among Adults With Dermatomyositis in the United States
Authors: Kwa Michael C. , Ardalan Kaveh , Laumann Anne E. , Silverberg Jonathan I. 
Published: May 2017

ObjectiveTo determine the prevalence and risk factors for hospitalization with dermatomyositis and assess inpatient burden of dermatomyositis.MethodsData on 72,651,487 hospitalizations from the 2002–2012 Nationwide Inpatient Sample, a 20% stratified sample of all acute‐care hospitalizations in the US, were analyzed. International Classification of Diseases, Ninth Revision, Clinical Modification coding was used to identify hospitalizations with a diagnosis of dermatomyositis.ResultsThere were 9,687 and 43,188 weighted admissions with a primary or secondary diagnosis of dermatomyositis, respectively. In multivariable logistic regression models with stepwise selection, female sex (logistic regression: adjusted odds ratio 2.05 [95% confidence interval (95% CI) 1.80, 2.34]), nonwhite race (African American: 1.68 [1.57, 1.79]; Hispanic: 2.38 [2.22, 2.55]; Asian: 1.54 [1.32, 1.81]; and multiracial/other: 1.65 [1.45, 1.88]), and multiple chronic conditions (2–5: 2.39 [2.20, 2.60] and ≥6: 2.80 [2.56, 3.07]) were all associated with higher rates of hospitalization for dermatomyositis. The weighted total length of stay (LOS) and inflation‐adjusted cost of care for patients with a primary inpatient diagnosis of dermatomyositis was 80,686 days and $168,076,970, with geometric means of 5.38 (95% CI 5.08, 5.71) and $11,682 (95% CI $11,013, $12,392), respectively. LOS and costs of hospitalization were significantly higher in patients with dermatomyositis compared to those without. Notably, race/ethnicity was associated with increased LOS (log‐linear regression: adjusted β [95% CI] for African American: 0.14 [0.04, 0.25] and Asian: 0.38 [0.22, 0.55]) and cost of care (Asian: 0.51 [0.36, 0.67]).ConclusionThere is a significant and increasing inpatient burden for dermatomyositis in the US. There appear to be racial differences, as nonwhites have higher prevalence of admission, increased LOS, and cost of care.
Reductive Trapping of [(OC)5W–W(CO)5]2− in a Mixed‐Valent SmII/III Calix[4]pyrrolide Sandwich
Authors: Deacon Glen B. , Guo Zhifang , Junk Peter C. , Wang Jun 
Published: May 2017

AbstractReduction of tungsten hexacarbonyl by the divalent samarium(II) complex [Sm2(N4Et8)(thf)4] ((N4Et8)4−=meso‐octaethylcalix[4]pyrrolide) in toluene at ambient temperature gave the remarkable heteronuclear mixed‐valent samarium(II/III)/tungsten complex [{(thf)2SmII(N4Et8)SmIII(thf)}2{(μ‐OC)2W2(CO)8}], which features the trapping of a rare [W2(CO)10]2− anion with an unsupported W−W bond.
An Organoruthenium Anticancer Agent Shows Unexpected Target Selectivity For Plectin
Authors: Meier Samuel M. , Kreutz Dominique , Winter Lilli , Klose Matthias H. M. , Cseh Klaudia , Weiss Tamara , Bileck Andrea , Alte Beatrix , Mader Johanna C. , Jana Samir , Chatterjee Annesha , Bhattacharyya Arindam , Hejl Michaela , Jakupec Michael A. , Heffeter Petra , Berger Walter , Hartinger Christian G. , Keppler Bernhard K. , Wiche Gerhard , Gerner Christopher 
Published: May 2017

AbstractOrganometallic metal(arene) anticancer agents require ligand exchange for their anticancer activity and this is generally believed to confer low selectivity for potential cellular targets. However, using an integrated proteomics‐based target‐response profiling approach as a potent hypothesis‐generating procedure, we found an unexpected target selectivity of a ruthenium(arene) pyridinecarbothioamide (plecstatin) for plectin, a scaffold protein and cytolinker, which was validated in a plectin knock‐out model in vitro. Plectin targeting shows potential as a strategy to inhibit tumor invasiveness as shown in cultured tumor spheroids while oral administration of plecstatin‐1 to mice reduces tumor growth more efficiently in the invasive B16 melanoma than in the CT26 colon tumor model.
(NHC)NiH‐Catalyzed Intermolecular Regio‐ and Diastereoselective Cross‐Hydroalkenylation of Endocyclic Dienes with α‐Olefins
Authors: Lian Xiaoyan , Chen Weihao , Dang Liang , Li Yuchen , Ho Chun‐Yu 
Published: May 2017

AbstractHighly selective cross‐hydroalkenylations of endocyclic 1,3‐dienes at the least substituted site with α‐olefins were achieved with a set of neutral (NHC)NiIIH(OTf) catalysts and cationic NiII catalysts with a novel NHC ligand. Under heteroatom assistance, skipped dienes were obtained in good yields, often from equal amounts of the two substrates and at a catalyst loading of 2–5 mol %. Rare 4,3‐product selectivity (i.e., with the H atom at C4 and the alkenyl group at C3 of the diene) was observed, which is different from the selectivity of known dimerizations of α‐olefins with both acyclic Co and Fe systems. The influence of the various substituents on the NHC, 1,3‐diene, and α‐olefin on the chemo‐, regio‐, and diastereoselectivity was studied. High levels of chirality transfer were observed with chiral cyclohexadiene derivatives.
The Practical Sense of Protection: A Discussion Paper on the Reporting of Child Abuse in Africa and whether International Standards Actually Help Keep Children Safe
Authors: Walker‐Simpson Karen 
Published: May 2017

International child protection standards aim to ensure that non‐governmental organisations ‘do no harm’ but the current approach to reporting abuse may actually leave children unprotected and, in some cases, expose them to greater risk. This discussion paper gives voice to concerns raised by local practitioners in Africa and places them within the context of available research in order to stimulate a debate aimed at enhancing the impact of current safeguards. Drawing on systems theory and the work of Pierre Bourdieu, the article illustrates how the current model of reporting often fails to take into account the significant disconnect between formal and informal protection mechanisms, as well as the unpredictability of individual decision‐making. Examples from research and practitioner experience illustrate how reporting procedures may provide a route to protection which is impractical and undesirable to local people, and may ultimately be unhelpful to local practitioners. The article calls for further research to inform changes to the current approach and for a review of funding requirements in order that local organisations have greater scope to engage communities in the co‐creation of procedures, thereby indigenising responses to ensure that they are realistic and genuinely respond to the specificities of children's lives.‘The current approach to reporting abuse may actually leave children unprotected’Key Practitioner Messages

Formal reporting procedures may actually offer routes to protection that are inaccessible or unacceptable to local people.
Reporting procedures should be developed with a much greater participation of local people.
There is a need for investment in piloting and implementing locally led approaches to capacity building.
The engagement of donors is critical in order to develop a new approach to evaluating ‘child safe’ organisations.
‘Procedures should be developed with a much greater participation of local people’