bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protostellar birth with ambipolar and ohmic diffusion
Authors: Vaytet N. , Commerçon B. , Masson J. , González M. , Chabrier G. 
Published: February 2018

Context. The transport of angular momentum is fundamental during the formation of low-mass stars; too little removal and rotation ensures stellar densities are never reached, too much and the absence of rotation means no protoplanetary disks can form. Magnetic diffusion is seen as a pathway to resolving this long-standing problem.
Aims. We aim to investigate the impact of including resistive magnetohydrodynamics (MHD) in simulations of the gravitational collapse of a 1 M⊙ gas sphere, from molecular cloud densities to the formation of the protostellar seed; the second Larson core.
Methods. We used the adaptive mesh refinement code RAMSES to perform two 3D simulations of collapsing magnetised gas spheres, including self-gravity, radiative transfer in the form of flux-limited diffusion, and a non-ideal gas equation of state to describe H2 dissociation which leads to the second collapse. The first run was carried out under the ideal MHD approximation, while ambipolar and ohmic diffusion was incorporated in the second calculation using resistivities computed from an equilibrium chemical network.
Results. In the ideal MHD simulation, the magnetic field dominates the energy budget everywhere inside and around the first hydrostatic core, fueling interchange instabilities and driving a low-velocity outflow above and below the equatorial plane of the system. High magnetic braking removes essentially all angular momentum from the second core. On the other hand, ambipolar and ohmic diffusion create a barrier which prevents amplification of the magnetic field beyond 0.1 G in the first Larson core which is now fully thermally supported. A significant amount of rotation is preserved and a small Keplerian-like disk forms around the second core. The ambipolar and ohmic diffusions are effective at radii below 10 AU, indicating that a least ~1 AU is necessary to investigate the angular momentum transfer and the formation of rotationally supported disks. Finally, when studying the radiative efficiency of the first and second core accretion shocks, we found that it can vary by several orders of magnitude over the 3D surface of the cores.
Conclusions. This proves that magnetic diffusion is a prerequisite to star formation. Not only does it enable the formation of protoplanetary disks in which planets will eventually form, it also plays a determinant role in the formation of the protostar itself.
News from the NA61/SHINE experiment
Authors: Šuša Tatjana 
Published: February 2018

The main goals of the NA61/SHINE experiment at the CERN SPS are the search for the critical point of strongly interacting matter and the study of the properties of the onset of deconfinement. These aims are pursued by performing a two-dimensional scan of the phase diagram of strongly interacting matter by varying the momentum and size of the colliding nuclei.
This contribution summarises the latest results from the NA61/SHINE experiment, in particular, new results on spectra and yields of ϕ meson in p+p interactions at 40, 80 and 158 GeV/c and K+ and K- production in central Be+Be collisions at mid-rapidity. In addition, results on system size dependence of particle yield ratios and fluctuations are presented.
Stick-slip and Torsional Friction Factors in Inclined Wellbores
Authors: Aarsnes Ulf Jakob F. , Shor Roman J. 
Published: February 2018

Stick slip is usually considered a phenomenon of bit-rock interaction, but is also often observed in the field with the bit off bottom. In this paper we present a distributed model of a drill string with an along-string Coulomb stiction to investigate the effect of borehole inclination and borehole friction on the incidence of stick-slip. This model is validated with high frequency surface and downhole data and then used to estimate static and dynamic friction.
A derivation of the torsional drill string model is shown and includes the along-string Coulomb stiction of the borehole acting on the string and the ‘velocity weakening’ between static and dynamic friction. The relative effects of these two frictions is investigated and the resulting drillstring behavior is presented. To isolate the effect of the along-string friction from the bit-rock interaction, field data from rotational start-ups after a connection (with bit off bottom) is considered. This high frequency surface and downhole data is then used to validate the surface and downhole behavior predicted by the model.
The model is shown to have a good match with the surface and downhole behavior of two deviated wellbores for depths ranging from 1500 to 3000 meters. In particular, the model replicates the amplitude and period of the oscillations, in both the topside torque and the downhole RPM, as caused by the along-string stick slip. It is further shown that by using the surface behavior of the drill-string during rotational startup, an estimate of the static and dynamic friction factors along the wellbore can be obtained, even during stick-slip oscillations, if axial tension in the drillstring is considered. This presents a possible method to estimate friction factors in the field when off-bottom stick slip is encountered, and points in the direction of avoiding stick slip through the design of an appropriate torsional start-up procedure without the need of an explicit friction test.
The image of the empty hands
Authors: Jacobsson Diana 
Published: February 2018

Abstract
This article examines the relationship between media and politics by focusing on the question of political responsibility and public accountability, and how this is negotiated in news journalism during an industrial crisis. The empirical analysis focuses on two dimensions of the news report: (1) the political performances and argument strategies; how leading politicians introduce, explain or defend their decisions, actions and points of view, and (2) how the dominant discourses of politics are reproduced, negotiated or opposed, in the journalistic recontextualization. The study suggests that news journalism reproduces and strengthens the neoliberal logic when it adapts to hegemonic problem descriptions and the dominant political frame of the crisis, in terms of what caused it, as well as how it should be solved and by whom. This analysis of the dynamics between political performance and how the question of political responsibility and accountability is represented by journalism provides knowledge of discourses regarding crisis in a specific political regime, and also contributes to the discussion about the relationship between journalistic space and political power within the hegemonic frame of neoliberalism.
Templates in child language
Authors: Vihman Marilyn , Wauquier Sophie 
Published: February 2018

Abstract
To what extent do developmental templates, or idiosyncratic child word patterns, reflect (i) universal tendencies of neurophysiologically grounded production, (ii) perceptually-based guidance due to the frequency of occurrence in input speech or to the rhythmic patterning of the adult language, or (iii) formal principles of phonological structure? We will argue here that all of these elements play a role in the emergence of these child structures, which constitute the first evidence of phonology in the child. We focus on the first-word period and provide evidence of both cross-linguistic commonalities and typological differences, which reflect the structure of the ambient language as perceived and filtered by the child. We then focus in on the role of template formation in individual children.
Retrieving meaning from noun and verb grammatical contexts
Authors: Veneziano Edy , Parisse Christophe 
Published: February 2018

Abstract
Ninety French-speaking children aged 2 to 4 years were presented with short utterances containing homophonous or nonce words whose object or action meaning was identifiable on the sole basis of the preceding grammatical morpheme. Items in noun and verb contexts were presented to the same children in order to assess their ability to provide appropriate contrastive interpretations. Results show that, at all ages, items were correctly identified beyond chance, with 4-year-olds outperforming the 2- and 3-year-olds. Individually, however, only part of the children, even in the older group, performed beyond chance level, suggesting substantial interindividual variability and difficulties, still present at these ages, to tackle situations offering minimal information. A case study of the developmental relation between production and comprehension is also presented.
Cross-linguistic variation in children’s multimodal utterances
Authors: Özyürek Aslı 
Published: February 2018

Abstract
Our ability to use language is multimodal and requires tight coordination between what is expressed in speech and in gesture, such as pointing or iconic gestures that convey semantic, syntactic and pragmatic information related to speakers’ messages. Interestingly, what is expressed in gesture and how it is coordinated with speech differs in speakers of different languages. This paper discusses recent findings on the development of children’s multimodal expressions taking cross-linguistic variation into account. Although some aspects of speech-gesture development show language-specificity from an early age, it might still take children until nine years of age to exhibit fully adult patterns of cross-linguistic variation. These findings reveal insights about how children coordinate different levels of representations given that their development is constrained by patterns that are specific to their languages.
Gesture and speech in adults’ and children’s narratives
Authors: Colletta Jean-Marc , Kunene Nicolas Ramona , Guidetti Michèle 
Published: February 2018

Abstract
This chapter reports on a cross-linguistic developmental study comparing speech and gesture produced in narratives by adults and children speaking either French (a non-pro-drop Romance language) or Zulu (a pro-drop Bantu language). We asked 72 participants (French: 12 adults and 24 children; Zulu: 12 adults and 24 children) to narrate a short silent cartoon. Zulu narratives were more detailed and contained fewer comments than the French. Zulu-speaking participants produced more representational and fewer pragmatic gestures than their French-speaking counterparts. Language differences do not explain this result. Rather, the findings support the gesture-speech co-expressivity framework and suggest an impact of literacy practice norms on multimodal narrative performance during later language acquisition.
Conversational partners and common ground
Authors: Clark Eve V. 
Published: February 2018

Abstract
Children’s early exposure to and experience with language varies. They differ in how much conversational interaction they have with more expert adult speakers, which affects both speed of processing and early vocabulary acquisition. Another source of variation is how many interlocutors children interact with. Interlocutors are male or female, use different dialects, and know differing amounts about the child’s daily routines. Here, how much practice children have with interlocutors inside and outside the family affects how well children can establish and make use of common ground. Children also differ in how much practice they have, early on, in making themselves understood to others, and this affects how readily they can establish and then add to common ground with each new interlocutor.
Genome-wide approaches to understanding and improving complex traits in aquaculture species.
Authors: Palaiokostas C. , Houston R. D. 
Published: February 2018

Abstract
The rapid drop in cost and increase in throughput of nucleic acid sequencing has provided many opportunities for aquaculture genetics and breeding. Genome-wide genetic marker data can now be readily generated in a cost-effective manner, even for species without extensive prior genomic tools. The result is that genome-wide association studies (GWAS) and genomic selection (GS) in aquaculture species are becoming increasingly routine. With only a small percentage of global aquaculture production obtained through selective breeding, it holds tremendous potential for the industry. GWAS and GS can help realize this potential, and the last 5 years has seen numerous studies in aquaculture species focusing mainly on growth-related and disease resistance traits. The current review discusses background information relating to methods of using genome-wide marker data for GWAS and GS, and discusses lessons learned through their practical implementations in commercial aquaculture breeding for genetic improvement. Future directions for these techniques and technologies are discussed.
Podocyte‐derived microparticles promote proximal tubule fibrotic signaling via p38 MAPK and CD36
Authors: Munkonda Mercedes N. , Akbari Shareef , Landry Chloe , Sun Suzy , Xiao Fengxia , Turner Maddison , Holterman Chet E. , Nasrallah Rania , Hébert Richard L. , Kennedy Christopher R. J. , Burger Dylan 
Published: February 2018

ABSTRACTTubulointerstitial fibrosis is a hallmark of advanced diabetic kidney disease that is linked to a decline in renal function, however the pathogenic mechanisms are poorly understood. Microparticles (MPs) are 100–1000 nm vesicles shed from injured cells that are implicated in intercellular signalling. Our lab recently observed the formation of MPs from podocytes and their release into urine of animal models of type 1 and 2 diabetes and in humans with type 1 diabetes. The purpose of the present study was to examine the role of podocyte MPs in tubular epithelial cell fibrotic responses. MPs were isolated from the media of differentiated, untreated human podocytes (hPODs) and administered to cultured human proximal tubule epithelial cells (PTECs). Treatment with podocyte MPs increased p38 and Smad3 phosphorylation and expression of the extracellular matrix (ECM) proteins fibronectin and collagen type IV. MP‐induced responses were attenuated by co‐treatment with the p38 inhibitor SB202190. A transforming growth factor beta (TGF‐β) receptor inhibitor (LY2109761) blocked MP‐induced Smad3 phosphorylation and ECM protein expression but not p38 phosphorylation suggesting that these responses occurred downstream of p38. Finally, blockade of the class B scavenger receptor CD36 completely abrogated MP‐mediated p38 phosphorylation, downstream Smad3 activation and fibronectin/collagen type IV induction. Taken together our results suggest that podocyte MPs interact with proximal tubule cells and induce pro‐fibrotic responses. Such interactions may contribute to the development of tubular fibrosis in glomerular disease.
P026 The impact of trophic effects of multi strain probiotic preparation on paracellular permeability
Authors: Petito V , Laterza L , Graziani C , Lucchetti D , Lopetuso L , Sgambato A , Scaldaferri F , Gasbarrini A 
Published: February 2018

Abstract

Background
Probiotics are defined as live, non-pathogenic bacteria that confer health benefits beyond their nutritional value. Particularly VSL#3, a probiotic mix containing four strains of Lactobacilli (L. paracasei, L. plantarum, L. acidophilus, and L. delbrueckii subsp. bulgaricus*), three strains of Bifidobacteria (B. longum**, B. infantis**, B. breve) and Streptococcus thermophilus, has demonstrated efficacy in the management of diseases characterised by increased intestinal permeability such as irritable bowel syndrome and ulcerative colitis. The aim of the present study was to evaluate the mechanism of action of VSL#3 to reduce intestinal permeability, and its effect in modulating the activity on tight junctions, focusing on the effects of secreted bioactive factors. *Recently reclassified as L. helveticus. **Recently reclassified as B. animalis subsp. lactis.

Methods
Two different lots of VSL#3 (Manufacturer: Nutrilinea Srl, Gallarate (VA), Italy) were used. Caco2 and HT29 cell lines were treated with a conditioning media (CM) prepared using 1g of probiotic formula grown in D-MEM cell culture medium (free of serum and antibiotics) at 37°C for 48 h without shaking and in anaerobic conditions. The effects of probiotic on proliferations of cells were evaluated by cell growth curve and MTT assay. The effect on apoptosis will be analysed by cytometry using double staining with Annexin V-FITC and Propidium Iodide, as well as it is well established. Furthermore, the effect on expression of tight junctions, in particular claudin-2, occludin, and ZO-1, will be investigated by western blot analysis.

Results
The multistrain probiotic formula, in particular the more concentrate CM (1:10) increase Caco2 and HT29 cells proliferation and the percentage of metabolic cell activity (up 20%), together with a decrease of 90% of apoptotic cells in the presence of CM. These trophic effects may have an impact on paracellular permeability. The expression of tight junction proteins increase in 24 h for claudin and ZO-1, and after 48 h of treatment in case of occludin. Also the densitometry and the ratio between of relative density of protein and endogenous control (β-actin) confirms these data. The results are the same using two different lots.

Conclusions
These preliminary data in vitro could be able to explain how VSL#3 works at intestinal mucosa level, in particular by secretion of factors that enhances barrier integrity. The proliferative stimuli and the increase of expression of tight junction proteins are consistent with an effect on mucosa regeneration and re-epithelization. Other experiments, also on other intestinal cell line, are necessary to deeply understand the mechanism of action of this kind of probiotic formula.
Telomere Length and Depression Among Ex-Prisoners of War: The Role of Subjective Age
Authors: Lahav Yael , Avidor Sharon , Stein Jacob Y , Zhou Xiao , Solomon Zahava 
Published: February 2018

AbstractObjectivesExposure to captivity increases the risk for multiple disturbances that may intensify during old age. In later phases of life, former-prisoners-of-war (ex-POWs) may suffer from depression as well as from accelerated aging, manifested in older subjective age and leukocyte telomere shortening. The current study assesses the link between these varied facets of increased vulnerability during old age and explores (a) the associations between subjective age and telomere length; (b) the mediating role of changes in subjective age over time within the associations between depression and telomere length.MethodsEighty-eight ex-POWs were assessed prospectively 30 (T1), 35 (T2), and 45 (T3) years after the 1973 Israeli Yom-Kippur War. Depression was assessed at T1; subjective age was assessed at T2 and T3; and telomere length and control variables were assessed at T3.ResultsOlder subjective age at T3 was associated with concurrent shorter telomeres, beyond the effect of chronological age. Change in subjective age between T2 and T3 mediated the relations between depression at T1 and shorter telomeres at T3 beyond the effects of control variables.DiscussionFindings suggest that the detrimental ramifications of accelerated subjective age involve premature cellular senesces, and may explain the relation between depression and accelerated aging processes among trauma victims. Hence, clinical interventions may seek to address accelerated subjective age among trauma survivors who suffer from depression.
Impact of the CMS No-Pay Policy on Hospital-Acquired Fall Prevention Related Practice Patterns
Authors: Fehlberg Elizabeth A , Lucero Robert J , Weaver Michael T , McDaniel Anna M , Chandler Michelle , Richey Phyllis A , Mion Lorraine C , Shorr Ronald I 
Published: February 2018

AbstractBackground and ObjectivesIn October 2008, the Centers for Medicare & Medicaid Services (CMS) stopped reimbursing hospitals for costs related to patient falls. This study aimed to examine whether the CMS no-pay policy influenced four fall prevention practices: bed alarms, sitters, room changes, and physical restraints.Research Design and MethodsUsing electronic medical record data collected from four hospitals between 2005 and 2010, this secondary observational analysis examined the associations between the CMS no-pay policy and nursing interventions and medical orders related to fall prevention. Multivariable generalized linear mixed models with logit link function and accommodation for matching was used to assess the associations between the CMS no-pay policy and nursing interventions and medical orders.ResultsAfter the CMS policy change, nurses were more likely to perform one or more fall-related interventions (adjusted odds ratio (aOR): 1.667; 95% confidence interval (CI): 1.097–2.534). Of the four prevention practices, the use of bed alarms (aOR: 2.343; 95% CI: 1.409–3.897) increased significantly after the CMS policy change.Discussion and ImplicationsThe CMS no-pay policy increased utilization of fall prevention strategies despite little evidence that these measures prevent falls.
Common octopus settled in human-altered Mediterranean coastal waters: from individual home range to population dynamics
Authors: Arechavala-Lopez P , Minguito-Frutos M , Follana-Berná G , Palmer M 
Published: February 2018

Abstract
A spatially explicit capture-recapture (SCR) model was applied to estimate simultaneously population parameters and individual activity (i.e. home range size) of O. vulgaris, based on experimental mark-recapture data in a human-altered Mediterranean coastal area. Seventy-two octopuses were captured, tagged with subcutaneous PIT-tags and released. Nineteen tagged individuals were recaptured (recapture rate: 26.4%) in the same area over the study period, which spanned over 6 months. Population sizes and densities decreased over the study period, from 337 octopuses (8 ind. ha−1) in September-October to 105 octopuses (2.5 ind. ha−1) in February-March. The highest recruitment probability was estimated to occur at the beginning of the study but it clearly decreased over time, while mortality probability during a fishing period slightly increased. Mean specific growth rate was 0.82 ± 0.11 day−1. Individual home range or activity area ranged from 2.8 ha to 7.3 ha (median home range radius: 121.8 m). Overall, these results suggest that human-altered coastal habitats, which are characterized by abundant shelters, abundant food and absence of predators, can act as settlement and growth areas for juveniles and adults of O. vulgaris. Furthermore, the methodologies applied in this study are recommended as innovative tools to improve management actions of coastal resources.