bluuebunny/crossref_metadata_2025_split huggingface dataset:
Substituent effect on supercapacitive performances of conducting polymer‐based redox electrodes: Poly(3′,4′‐bis(alkyloxy) 2,2′:5′,2″‐terthiophene) derivatives
Authors: Yiğit Deniz , Aykan Melis , Güllü Mustafa 
Published: December 2017

ABSTRACTThis work reports the synthesis of novel poly(3′,4′‐bis(alkyloxy)terthiophene) derivatives (PTTOBu, PTTOHex, and PTTOOct) and their supercapacitor applications as redox‐active electrodes. The terthiophene‐based conducting polymers have been derivatized with different alkyl pendant groups (butyl‐, hexyl‐, and octyl‐) to explore the effect of alkyl chain length on the surface morphologies and pseudocapacitive properties. The electrochemical performance tests have revealed that the length of alkyl substituent created a remarkable impact over the surface morphologies and charge storage properties of polymer electrodes. PTTOBu, PTTOHex, and PTTOOct‐based electrodes have reached up to specific capacitances of 94.3, 227.3, and 443 F g−1 at 2.5 mA cm−2 constant current density, respectively, in a three‐electrode configuration. Besides, these redox‐active electrodes have delivered satisfactory energy densities of 13.5, 29.3, and 60.7 W h kg−1 and power densities of 0.98, 1, and 1.1 kW kg−1 with good capacitance retentions after 10,000 charge/discharge cycles in symmetric solid‐state micro‐supercapacitor devices. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 480–495
Tuning the localization of finely dispersed cellulose nanocrystal in poly (lactic acid)/bio‐polyamide11 blends
Authors: Heshmati Vahid , Kamal Musa R. , Favis Basil D. 
Published: December 2017

ABSTRACTA versatile approach to control the localization of cellulose nanocrystal (CNC) in PLA/PA11 blends is presented. A PEO/CNC mixture with a high level of CNC dispersion is prepared through a combination of high pressure homogenization and freeze‐drying. The prepared PEO/CNC mixture is then incorporated into the PLA/PA11 blends using two different strategies. Typically for CNC/PLA/PA11, the CNCs selectively localize in PA11. However, PEO‐coated CNC particles segregate into PLA irrespective of whether the PEO/CNC mixture is premixed with PLA or PA11. It is suggested that a strong interaction between PEO and CNC particles combined with the PLA/PEO miscibility facilitates the localization of PEO‐coated CNC in the PLA. The localization of PEO‐coated CNC in the PLA has no effect on the morphology of the PLA‐5PEO/PA11 with matrix/dispersed phase form. However, 2 wt % PEO‐coated CNC in the co‐continuous (PLA‐5PEO)/PA11 50/50 vol % blend diminishes the phase thickness from 11 ± 1 to 4 ± 1.5 μm. This is attributed to a retarded relaxation of the PLA phase. This work outlines a strategy to control the CNC localization into a given polymeric phase in a binary polymer–polymer mixture. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2018, 56, 576–587
Molecular architectures of Pen and Pal: Key enzymes required for CMP‐pseudaminic acid biosynthesis in Bacillus thuringiensis
Authors: Delvaux Nathan A. , Thoden James B. , Holden Hazel M. 
Published: December 2017

AbstractBacillus thuringiensis is a soil‐dwelling Gram positive bacterium that has been utilized as a biopesticide for well over 60 years. It is known to contain flagella that are important for motility. One of the proteins found in flagella is flagellin, which is post‐translationally modified by O‐glycosylation with derivatives of pseudaminic acid. The biosynthetic pathway for the production of CMP‐pseudaminic acid in B. thuringiensis, starting with UDP‐N‐acetyl‐d‐glucosamine (UDP‐GlcNAc), requires seven enzymes. Here, we report the three‐dimensional structures of Pen and Pal, which catalyze the first and second steps, respectively. Pen contains a tightly bound NADP(H) cofactor whereas Pal is isolated with bound NAD(H). For the X‐ray analysis of Pen, the site‐directed D128N/K129A mutant variant was prepared in order to trap its substrate, UDP‐GlcNAc, into the active site. Pen adopts a hexameric quaternary structure with each subunit showing the bilobal architecture observed for members of the short‐chain dehydrogenase/reductase superfamily. The hexameric quaternary structure is atypical for most members of the superfamily. The structure of Pal was determined in the presence of UDP. Pal adopts the more typical dimeric quaternary structure. Taken together, Pen and Pal catalyze the conversion of UDP‐GlcNAc to UDP‐4‐keto‐6‐deoxy‐l‐N‐acetylaltrosamine. Strikingly, in Gram negative bacteria such as Campylobacter jejuni and Helicobacter pylori, only a single enzyme (FlaA1) is required for the production of UDP‐4‐keto‐6‐deoxy‐l‐N‐acetylaltrosamine. A comparison of Pen and Pal with FlaA1 reveals differences that may explain why FlaA1 is a bifunctional enzyme whereas Pen and Pal catalyze the individual steps leading to the formation of the UDP‐sugar product. This investigation represents the first structural analysis of the enzymes in B. thuringiensis that are required for CMP‐pseudaminic acid formation.
Arboricity and spanning‐tree packing in random graphs
Authors: Gao Pu , Pérez‐Giménez Xavier , Sato Cristiane M. 
Published: December 2017

AbstractWe study the arboricity and the maximum number of edge‐disjoint spanning trees of the classical random graph . For all , we show that, with high probability, is precisely the minimum of and , where is the minimum degree of the graph and denotes the number of edges. Moreover, we explicitly determine a sharp threshold value for such that the following holds. Above this threshold, equals and equals . Below this threshold, equals , and we give a two‐value concentration result for the arboricity in that range. Finally, we include a stronger version of these results in the context of the random graph process where the edges are randomly added one by one. A direct application of our result gives a sharp threshold for the maximum load being at most in the two‐choice load balancing problem, where .
Lung Injury Repair by Transplantation of Adult Lung Cells Following Preconditioning of Recipient Mice
Authors: Milman Krentsis Irit , Rosen Chava , Shezen Elias , Aronovich Anna , Nathanson Bar , Bachar-Lustig Esther , Berkman Neville , Assayag Miri , Shakhar Guy , Feferman Tali , Orgad Ran , Reisner Yair 
Published: December 2017

AbstractRepair of injured lungs represents a longstanding therapeutic challenge. We recently demonstrated that human and mouse embryonic lung tissue from the canalicular stage of development are enriched with lung progenitors, and that a single cell suspension of canalicular lungs can be used for transplantation, provided that lung progenitor niches in the recipient mice are vacated by strategies similar to those used in bone marrow transplantation. Considering the ethical limitations associated with the use of fetal cells, we investigated here whether adult lungs could offer an alternative source of lung progenitors for transplantation. We show that intravenous infusion of a single cell suspension of adult mouse lungs from GFP+ donors, following conditioning of recipient mice with naphthalene and subsequent sublethal irradiation, led to marked colonization of the recipient lungs, at 6–8 weeks post-transplant, with donor derived structures including epithelial, endothelial, and mesenchymal cells. Epithelial cells within these donor-derived colonies expressed markers of functionally distinct lung cell types, and lung function, which is significantly compromised in mice treated with naphthalene and radiation, was found to be corrected following transplantation. Dose response analysis suggests that the frequency of patch forming cells in adult lungs was about threefold lower compared to that found in E16 fetal lungs. However, as adult lungs are much larger, the total number of patch forming cells that can be collected from this source is significantly greater. Our study provides proof of concept for lung regeneration by adult lung cells after preconditioning to vacate the pulmonary niche.
Which pathway to good ideas? An attention‐based view of innovation in social networks
Authors: Rhee Luke , Leonardi Paul M. 
Published: December 2017

Research Summary: This study introduces the notion of attention allocation in networks to argue that individuals with different types of network structure produce good ideas via different pathways. Using survey data on communication networks at a software company, we find that people with highly constrained networks generate good ideas by following a logic of interrogation, by which they focus their attention on information from a particular contact. Conversely, individuals with less constrained networks produce good ideas by following a logic of recombination, whereby they divide their attention to information coming from across multiple contacts. The results show that in highly constrained networks, interrogation is a more reliable pathway to good ideas than recombination. We discuss the implications of these findings for behavioral strategy, social networks, and innovation.Managerial Summary: People can develop good ideas when they recombine diverse information inputs shared by non‐redundant communication partners that span multiple local clusters. But, in an organization, most individuals are embedded in constrained networks of people who know each other and thus typically receive redundant information from work colleagues. This study suggests that they can innovate via a different pathway: through interrogation. We find that people who focus their attention on information coming from a particular person succeed at generating good ideas because they deeply interrogate local knowledge and develop domain‐specific insights.
Under the microscope: An experimental look at board transparency and director monitoring behavior
Authors: Li Weiwen , Krause Ryan , Qin Xin , Zhang Junsheng , Zhu Hang , Lin Shanshan , Xu Yuehua 
Published: December 2017

Research Summary: It is well known in corporate governance scholarship that independent directors differ in the vigilance with which they monitor corporate insiders. This difference depends largely on whether independent directors are concerned more with their public reputation or with their prospects in the director labor market. The explanation for this difference depends on an assumption of information asymmetry, however. In the present study, we relax the assumption of information asymmetry to examine how boardroom transparency affects directors’ monitoring behavior. Using a randomized experimental study of actual independent directors, we find that boardroom transparency amplifies the effect of directors’ inclinations toward either active or passive monitoring, with directors inclined toward vigilant monitoring becoming even more vigilant, and directors inclined toward passive monitoring becoming even more passive.Managerial Summary: In most advanced economies, the board's internal decision processes are either undisclosed or disclosed only to a very limited extent. It remains unknown, then, whether directors would behave differently if their behaviors were made public. We find that when their actions are disclosed to the public, directors concerned with their public reputations become more vigilant, whereas those concerned with their prospects for additional board seats become more passive in monitoring corporate insiders. Whereas regulatory bodies and corporate governance watchdogs have recently advocated for greater disclosure of the boardroom decision‐making process, our study suggests that such mandatory disclosure requirements can exacerbate, rather than alleviate, the problem of passive director monitoring.
Gold Nanoparticle‐Based Paper Sensor for Simultaneous Detection of 11 Benzimidazoles by One Monoclonal Antibody
Authors: Guo Lingling , Wu Xiaoling , Liu Liqiang , Kuang Hua , Xu Chuanlai 
Published: December 2017

AbstractA colloidal gold immunochromatographic assay based on a generic monoclonal antibody is developed for the simultaneous detection of benzimidazoles and metabolite residues in milk samples. The monoclonal antibody is prepared using 2‐(methoxycarbonylamino)‐3H‐benzimidazole‐5‐carboxylic acid as the hapten, and it can recognize 11 types of benzimidazoles simultaneously. The immunochromatographic strip is assembled and labeled using gold nanoparticles. This strip can detect 11 benzimidazoles including albendazole, albendazole s‐oxide, albendazole sulfone, fenbendazole, fenbendazole sulfone, flubendazole, mebendazole, parbendazole, oxfendazole, oxibendazole, and carbendazim within 15 min in milk samples. Results are obtained visually with the naked eye, and the cutoff values and the visual limit of detection values for these benzimidazoles are 25, 6.25, 12.5, 12.5, 50, 25, 50, 50, 50, 6.25, and 25 ng mL−1, and 6.25, 3.125, 3.125, 1.56, 12.5, 6.25, 12.5, 12.5, 6.25, 0.78, and 12.5 ng mL−1, respectively. Results are also obtained using a hand‐held strip scan reader, with calculated limit of detection values for these benzimidazoles of 0.83, 0.77, 1.83, 0.98, 7.67, 3.50, 3.96, 5.71, 0.92, 0.59, and 1.69 ng mL−1, respectively. In short, the developed paper sensor is a useful tool for rapid and simple screening of residues of benzimidazoles in milk samples.
Antireflux Surgery and Barrett’s Esophagus: Myth or Reality?
Authors: Herbella Fernando A. M. , Schlottmann Francisco , Patti Marco G. 
Published: December 2017

AbstractBackgroundIt may seem questionable if antireflux surgery still has a role in the management of patients with Barrett’s esophagus (BE) in the current era when antireflux surgery is facing a steady decline, obesity is increasing, pharmacologic treatment for gastroesophageal reflux disease (GERD) is in its splendor, and endoscopic techniques are used more frequently. It is questionable if patients with BE should be operated to stop GERD and to prevent cancer. The aim of this study was to determine the role of antireflux surgery in patients with BE.MethodsLiterature review.ResultsThe role of antireflux operations is, in fact, very controversial and neglected. BE is a different phenotype of GERD with a distinct pathophysiology linked to severe reflux of bile and acid, due to a marked anatomic disruption of the gastroesophageal barrier. Published series show that a fundoplication adequately controls GERD and symptoms in BE patients. A fundoplication (or even better a bile diversion antireflux procedure) may prevent esophageal adenocarcinoma.ConclusionsIn conclusion, a fundoplication efficiently controls GERD and symptoms in BE patients. A fundoplication (or even better a bile diversion procedure) may also prevent esophageal adenocarcinoma.
Lipid Emulsion Enriched in Omega‐3 PUFA Accelerates Wound Healing: A Placebo‐Controlled Animal Study
Authors: Peng Yi‐Chi , Yang Fwu‐Lin , Subeq Yi‐Maun , Tien Chin‐Chieh , Chao Yann‐Fen C. , Lee Ru‐Ping 
Published: December 2017

AbstractBackgroundThe Omega‐3 (ω‐3) polyunsaturated fatty acids (PUFAs) generate bioactive lipid mediators that reduce inflammation. The present study evaluated the effect of SMOFlipid containing ω‐3 PUFAs on wound healing.MethodsRats were divided into a SMOFlipid (SMOF) group and a 0.9% saline (placebo) group, with eight rats in each group. Wound excision was performed on the dorsal surface of each rat. In the SMOF group, 1 gm/kg SMOFlipid was dissolved in 3 mL saline as a treatment; in the placebo group, 3 mL saline was prepared as a treatment. The treatments were administered intravenously at an initial rate of 0.2 mL/kg body weight/h immediately after wounding, for 72 h. Blood samples were collected for white blood cell, tumor necrosis factor (TNF)‐α, interleukin (IL)‐6, and IL‐10 measurements at the baseline and at 1, 6, 12, 24, 48, and 72 h after intervention. Wound areas were measured over a 2‐week period after excision, and a histological examination was performed.ResultsCompared with the placebo group, SMOFlipid supplementation engendered significant decreases in the wound area on day 3 (78.28 ± 5.25 vs. 105.86 ± 8.89%), day 5 (72.20 ± 4.31 vs. 96.39 ± 4.72%), day 10 (20.78 ± 1.28 vs. 39.80 ± 10.38%), and day 14 (7.56 ± 0.61 vs. 15.10 ± 2.42%). The placebo group had a higher TNF‐α level than the SMOF group at 72 h. The IL‐10 level was higher in the SMOF group than in the placebo group at 48 h. Histological analysis revealed a higher rate of fibroblast distribution and collagen fiber organization in the SMOF group (P = 0.01).ConclusionSMOFlipid enriched in ω‐3 PUFA accelerates wound healing.
Concentration of Proteasome in the Blood Plasma of Children with Acute Appendicitis, Before and After Surgery, and Its Correlation with CRP
Authors: Matuszczak Ewa , Tylicka Marzena , Dębek Wojciech , Sankiewicz Anna , Gorodkiewicz Ewa , Hermanowicz Adam 
Published: December 2017

AbstractObjectiveThe determination of 20S proteasome concentration in the blood plasma of children with appendicitis and its correlation with CRP.Design and settingThirty‐one children with acute appendicitis, were randomly included into the study (age 5 years up to 17 years, mean age 11.5 + 1 years).ParticipantsThere were 17 girls and 14 boys. Eighteen healthy, age‐matched subjects, admitted for planned surgeries served as controls. Exclusion criteria were: severe preexisting infections, immunological or cardiovascular diseases that required long‐term medication, and complicated cases of appendicitis with perforation of appendix and/or peritonitis.Main outcome measuresThe 20S proteasome concentrations in the blood plasma of patients with acute appendicitis were highest before the surgery and were above the range of concentrations measured in controls, and the difference was statistically significant.ResultsThe 20S proteasome concentration measured 24 and 72 h after the operation, slowly decreased over time, and still did not reach the normal range, when compared with the concentration measured in controls (p < 0.05).Conclusions20S proteasome concentration may reflect the metabolic response to acute state inflammation, and the process of gradual ebbing of the inflammation. The method of operation—classic open appendectomy, or laparoscopic appendectomy, does not influence the general trend in 20S proteasome concentration.
Bilingual Cancer Genetic Education Modules for the Deaf Community: Development and Evaluation of the Online Video Material
Authors: Boudreault Patrick , Wolfson Alicia , Berman Barbara , Venne Vickie L. , Sinsheimer Janet S. , Palmer Christina 
Published: December 2017

AbstractHealth information about inherited forms of cancer and the role of family history in cancer risk for the American Sign Language (ASL) Deaf community, a linguistic and cultural community, needs improvement. Cancer genetic education materials available in English print format are not accessible for many sign language users because English is not their native or primary language. Per Center for Disease Control and Prevention recommendations, the level of literacy for printed health education materials should not be higher than 6th grade level (~ 11 to 12 years old), and even with this recommendation, printed materials are still not accessible to sign language users or other nonnative English speakers. Genetic counseling is becoming an integral part of healthcare, but often ASL users are not considered when health education materials are developed. As a result, there are few genetic counseling materials available in ASL. Online tools such as video and closed captioning offer opportunities for educators and genetic counselors to provide digital access to genetic information in ASL to the Deaf community. The Deaf Genetics Project team used a bilingual approach to develop a 37‐min interactive Cancer Genetics Education Module (CGEM) video in ASL with closed captions and quizzes, and demonstrated that this approach resulted in greater cancer genetic knowledge and increased intentions to obtain counseling or testing, compared to standard English text information (Palmer et al., Disability and Health Journal, 10(1):23–32, 2017). Though visually enhanced educational materials have been developed for sign language users with multimodal/lingual approach, little is known about design features that can accommodate a diverse audience of sign language users so the material is engaging to a wide audience. The main objectives of this paper are to describe the development of the CGEM and to determine if viewer demographic characteristics are associated with two measurable aspects of CGEM viewing behavior: (1) length of time spent viewing and (2) number of pause, play, and seek events. These objectives are important to address, especially for Deaf individuals because the amount of simultaneous content (video, print) requires cross‐modal cognitive processing of visual and textual materials. The use of technology and presentational strategies is needed that enhance and not interfere with health learning in this population.
Syndromale und nichtsyndromale orofaziale Spalten
Authors: Mangold Elisabeth , Kreiß Martina , Nöthen Markus M. 
Published: December 2017

Zusammenfassung
Orofaziale Spalten sind die zweithäufigste angeborene Fehlbildung. Die beiden häufigen Untergruppen sind die Formen der Lippen-Kiefer-Gaumen-Spalte (LKGS) und der reinen Gaumenspalte (GS). Beide können im Zuge zahlreicher Syndrome auftreten, LKGS sind häufiger nichtsyndromal (ca. 70 %) als GS (ca. 50 %). Nichtsyndromale Spalten sind multifaktoriell und bergen relativ geringe Wiederholungsrisiken für Angehörige. Manche syndromalen Spaltformen beruhen auf Chromosomenaberrationen, die meisten sind jedoch monogen. Das autosomal-dominante Van-der-Woude-Syndrom ist eine wichtige Differenzialdiagnose zu nichtsyndromalen Spaltformen, die sich nur durch Unterlippengrübchen von diesen unterscheidet, aber höhere Risiken für eine Spaltbildung bei Nachkommen birgt. Die Pränataldiagnostik orofazialer Spalten erfolgt sonographisch. Erfahrene Untersucher können LKGS in der 20. Schwangerschaftswoche diagnostizieren; die Detektion von GS ist schwieriger.
Efficiency of using spatial analysis for Norway spruce progeny tests in Sweden
Authors: Chen Zhiqiang , Helmersson Andreas , Westin Johan , Karlsson Bo , Wu Harry X. 
Published: December 2017

Abstract
Key message
Spatial analysis could improve the accuracy of genetic analyses, as well as increasing the accuracy of predicting breeding values and genetic gain for Norway spruce trials.

Context
Spatial analysis has been increasingly used in genetic evaluation of field trials in tree species. However, the efficiency of spatial analysis relative to the analysis using the conventional experimental designs or pre- and post-blocking method in Swedish genetic trials has not been systematically evaluated.

Aims
This study aims to examine the effectiveness of spatial analysis in improving the accuracy of predicting breeding values and genetic gain.

Methods
Spatial analysis, using separable first-order autoregressive processes of residuals in rows and columns, was used in nine types of trait classes from 145 field trials of Norway spruce (Picea abies (L.) Karst.) in Sweden.

Results
Ninety-six percent of variables (traits) were converged for the spatial model. Large trials with a large block variance tend to have a larger improvement from the model of experimental design to spatial model in accuracy. Growth and Pilodyn measurement traits showed greater improvements in log likelihood, accuracy, and genetic gain. Block variance was reduced by more than 80% for trait height and diameter using spatial analysis, indicating that it is more effective using both pre-blocking and post-blocking analyses in Swedish Norway spruce trials. The prediction accuracy for diameter and height for progeny breeding values showed an increase of 3.6 and 3.4%, respectively. The improvement of efficiency for growth traits is also related to the geographical location of test sites, tree age, number of survival trees, and the spacing of the trial.

Conclusion
The spatial analysis approach is more efficient in Swedish Norway spruce trials than the conventional methods using models based on the experimental design.