bluuebunny/crossref_metadata_2025_split huggingface dataset:
A quantitative threshold for high/low extent of urinary excretion of compounds in humans
Authors: Dave Rutwij A. , Morris Marilyn E. 
Published: April 2016

AbstractIn this study, a quantitative threshold was determined for the high/low extent of urinary excretion (UE) of compounds in humans, using a straightforward but robust statistical method known as receiver operating characteristic curve (ROC) analysis, and also 18 potential physicochemical determinants of UE were evaluated. Data on the percent of drug excreted unchanged into the urine, %Ae, were used to determine the threshold for high/low UE. Compounds can be divided into high/low UE groups using the threshold value of Ae = 16.8%, namely those with Ae > 16.8% are classified as high UE and those with Ae ≤ 16.8% as low UE. The %Ae negatively correlated with cLogP (r = −0.56); however, cLogP could not quantitatively predict the value of %Ae (R2adj. = 0.32). Several determinants of the extent of UE, including cLogP, ACD labs cLogP and ACD labs cLogD(pH=7.4), were successfully evaluated as a priori indicators of the extent of UE using two cut‐off values for each parameter. Moreover, 87% of the 90 compounds in the external validation set were correctly classified using this approach. Analysis of the physicochemical spaces of compounds in these two groups showed significant overlap, which hinders the a priori determination of the extent of UE of compounds using a single threshold/cut‐off value of simple physicochemical parameters. In conclusion, 16.8% is a quantitative threshold value to distinguish between high and low UE and new molecular entities with cLogP and ACD labs cLogP values of ≤0.7 and ≥1.0 and ACD labs cLogD(pH=7.4) values of ≤0.0 and ≥0.5 could be identified as exhibiting high and low UE, respectively. Copyright © 2016 John Wiley & Sons, Ltd.
Molecular crowding impacts the structure of apolipoprotein A‐I with potential implications on in vivo metabolism and function
Authors: Petrlova Jitka , Hilt Silvia , Budamagunta Madhu , Domingo‐Espín Joan , Voss John C. , Lagerstedt Jens O. 
Published: April 2016

ABSTRACTThe effect molecular crowding, defined as the volume exclusion exerted by one soluble inert molecule upon another soluble molecule, has on the structure and self‐interaction of lipid‐free apoA‐I were explored. The influence of molecular crowding on lipid‐free apoA‐I oligomerization and internal dynamics has been analyzed using electron paramagnetic resonance (EPR) spectroscopy measurements of nitroxide spin label at selected positions throughout the protein sequence and at varying concentrations of the crowding agent Ficoll‐70. The targeted positions include sites previously shown to be sensitive for detecting intermolecular interaction via spin–spin coupling. Circular dichroism was used to study secondary structural changes in lipid‐free apoA‐I imposed by increasing concentrations of the crowding agent. Crosslinking and SDS‐PAGE gel analysis was employed to further characterize the role molecular crowding plays in inducing apoA‐I oligomerization. It was concluded that the dynamic apoA‐I structure and oligomeric state was altered in the presence of the crowding agent. It was also found that the C‐terminal was slightly more sensitive to molecular crowding. Finally, the data described the region around residue 217 in the C‐terminal domain of apoA‐I as the most sensitive reporter of the crowding‐induced self‐association of apoA‐I. The implications of this behavior to in vivo functionality are discussed. © 2016 Wiley Periodicals, Inc. Biopolymers 105: 683–692, 2016.
Vertical integration of biochemistry and clinical medicine using a near‐peer learning model
Authors: Gallan Alexander J. , Offner Gwynneth D. , Symes Karen 
Published: April 2016

AbstractVertical integration has been extensively implemented across medical school curricula but has not been widely attempted in the field of biochemistry. We describe a novel curricular innovation in which a near‐peer learning model was used to implement vertical integration in our medical school biochemistry course. Senior medical students developed and facilitated a case‐based small group session for first year biochemistry students. Students were surveyed before and after the session on their attitudes about biochemistry, as well as the effectiveness of the session. Prior to the session, the students believed biochemistry was more important to understanding the basic science of medicine than it was to understanding clinical medicine or becoming a good physician. The session improved students' attitudes about the importance of biochemistry in clinical medicine, and after the session they now believe that understanding biochemistry is equally important to the basic sciences as clinical medicine. Students would like more sessions and believe the senior student facilitators were knowledgeable and effective teachers. The facilitators believe they improved their teaching skills. This novel combination of near‐peer learning and vertical integration in biochemistry provided great benefit to both first year and senior medical students, and can serve as a model for other institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):507–516, 2016.
Simultaneous determination of paeoniflorin from total glucosides of paeony in Sprague–Dawley rats and spontaneously hypertensive rats by high‐performance liquid chromatography–tandem mass spectrometry: in vivo and in vitro studies
Authors: Xiong Shan , Wang Yuyun 
Published: April 2016

AbstractPaeoniflorin is a well‐known monoterpene glucoside in the herbal drug that exhibits a number of biological activities. The pharmacokinetic characteristics of paeoniflorin from total glucosides of paeony in spontaneously hypertensive rats (SHR) are still unclear. It is essential to investigate the in vivo and in vitro pharmacokinetic differences of paeoniflorin from total glucosides of paeony in Sprague–Dawley (SD) and SHR. The in vivo pharmacokinetic data were analyzed using DAS 2.0 software and the in vitro metabolic characteristics were measured using rat hepatic microsomes. The concentration of paeoniflorin in biological samples was determined using high‐performance liquid chromatography–electrospray ionization tandem mass spectrometry method, which showed good precision and stability. The plasma concentration–time profiles of paeoniflorin following oral administration of total glucosides of paeony showed a single peak and there were significant differences in the mean values of AUC(0–t), AUC(0–∞), CLz/F and Tmax between SD and SHR (p < 0.05). The metabolic rate of paeoniflorin from total glucosides of paeony was slower in SHR than in SD rats (p < 0.05). The results might be useful in further applications of paeoniflorin and total glucosides of paeony. Copyright © 2016 John Wiley & Sons, Ltd.
In vivo injection of α‐bungarotoxin to improve the efficiency of motor endplate labeling
Authors: Chen Wentao , Yu Tingting , Chen Bo , Qi Yisong , Zhang Peixun , Zhu Dan , Yin Xiaofeng , Jiang Baoguo 
Published: April 2016

AbstractIntroductionMotor endplates are composed of a motor neuron terminal and muscle fiber and are distributed in skeletal muscle, causing muscle contraction. However, traditional motor endplate staining methods are limited to the observation of partial skeletal muscle. The procedure was time‐consuming due to strict incubation conditions, and usually provided unsatisfactory results. We explored a novel method to label motor endplate rapidly by in vivo injection of fluorescent α‐bungarotoxin.MethodsFifty‐two mice were randomly divided into two groups, an experiment group (n = 50), and a contrast group (n = 2). In experiment group, α‐bungarotoxin was injected via the caudal vein. The injection dosages were designated as 0.1, 0.2, 0.3, 0.4, and 0.5 μg/g. The experimental mice were divided into five subgroups of ten mice per group. The contrast group was only injected with 200 μL normal saline solution. Bilateral gastrocnemius were acquired for microscope analysis and optical clearing to seek specific fluorescent signal.ResultsA dose of 0.3 μg/g of α‐bungarotoxin with 1 h conjugation time could display the number and structure of motor endplate in plane view. Compared with the traditional procedure, this method was rapid, convenient, and time‐saving. Combined with the optical clearing technique, spatial distribution could also be seen, helping to better understand the stereoscopic view of motor endplate position in skeletal muscle.ConclusionsIn vivo injection of α‐bungarotoxin proved effective for studying motor endplate in skeletal muscle.
Synthesis and Kinetic Characterisation of Water‐Soluble Fluorogenic Acyl Donors for Transglutaminase 2
Authors: Wodtke Robert , Schramm Georg , Pietzsch Jens , Pietsch Markus , Löser Reik 
Published: April 2016

AbstractSmall glutamate‐containing peptides bearing coumarin derivatives as fluorescent leaving groups attached to the γ‐carboxylic acid group of the Glu residue were synthesised and investigated with regard to their potential to act as substrates for transglutaminase 2 (TGase 2). Their synthesis was accomplished by an efficient solid‐phase approach. The excellent water solubility of the compounds enabled their extensive kinetic characterisation in the context of TGase 2‐catalysed hydrolysis and aminolysis. The influence of the coumarin skeleton's substitution pattern on the kinetic properties was studied. Derivatives containing 7‐hydroxy‐4‐methylcoumarin (HMC) revealed properties superior to those of their 7‐hydroxycoumarin counterparts; analogous amides are not accepted as substrates. Z‐Glu(HMC)‐Gly‐OH, which exhibited the best substrate properties out of the investigated derivatives, was selected for representative kinetic characterisation of acyl acceptor substrates and irreversible inhibitors.
5′‐(E)‐Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA–GalNAc Conjugates
Authors: Parmar Rubina , Willoughby Jennifer L. S. , Liu Jingxuan , Foster Donald J. , Brigham Benjamin , Theile Christopher S. , Charisse Klaus , Akinc Akin , Guidry Erin , Pei Yi , Strapps Walter , Cancilla Mark , Stanton Matthew G. , Rajeev Kallanthottathil G. , Sepp‐Lorenzino Laura , Manoharan Muthiah , Meyers Rachel , Maier Martin A. , Jadhav Vasant 
Published: April 2016

AbstractSmall interfering RNA (siRNA)‐mediated silencing requires siRNA loading into the RNA‐induced silencing complex (RISC). Presence of 5′‐phosphate (5′‐P) is reported to be critical for efficient RISC loading of the antisense strand (AS) by anchoring it to the mid‐domain of the Argonaute2 (Ago2) protein. Phosphorylation of exogenous duplex siRNAs is thought to be accomplished by cytosolic Clp1 kinase. However, although extensive chemical modifications are essential for siRNA–GalNAc conjugate activity, they can significantly impair Clp1 kinase activity. Here, we further elucidated the effect of 5′‐P on the activity of siRNA–GalNAc conjugates. Our results demonstrate that a subset of sequences benefit from the presence of exogenous 5′‐P. For those that do, incorporation of 5′‐(E)‐vinylphosphonate (5′‐VP), a metabolically stable phosphate mimic, results in up to 20‐fold improved in vitro potency and up to a threefold benefit in in vivo activity by promoting Ago2 loading and enhancing metabolic stability.
Nucleosome Assembly Alters the Accessibility of the Antitumor Agent Duocarmycin B2 to Duplex DNA
Authors: Zou Tingting , Kizaki Seiichiro , Pandian Ganesh N. , Sugiyama Hiroshi 
Published: April 2016

AbstractTo evaluate the reactivity of antitumor agents in a nucleosome architecture, we conducted in vitro studies to assess the alkylation level of duocarmycin B2 on nucleosomes with core and linker DNA using sequencing gel electrophoresis. Our results suggested that the alkylating efficiencies of duocarmycin B2 were significantly decreased in core DNA and increased at the histone‐free linker DNA sites when compared with naked DNA conditions. Our finding that nucleosome assembly alters the accessibility of duocarmycin B2 to duplex DNA could advance its design as an antitumor agent.
Fundamental Differences between Group 8 Metals: Unexpected Oxidation State Preferences and Mechanisms in Ruthenium Borylene Complex Formation
Authors: Braunschweig Holger , Damme Alexander , Dewhurst Rian D. , Radacki Krzysztof , Weißenberger Felix , Wennemann Benedikt , Ye Qing 
Published: April 2016

AbstractThe reaction of the salts K[Ru(CO)3(PMe3)(SiR3)] (R=Me, Et) with Br2BDur or Cl2BDur (Dur=2,3,5,6‐Me4C6H) leads to both boryl and borylene complexes of divalent ruthenium, the former through simple salt elimination and the latter through subsequent CO loss and 1,2‐halide shift. The balance of products can be altered by varying the reaction conditions; boryl complexes can be favored by the addition of CO, and borylene complexes by removal of CO under vacuum. All of these products are in competition with the corresponding (aryl)(halo)(trialkylsilyl)borane, a reductive elimination product. The RuII borylene products and the mechanisms that form them are distinctly different from the analogous reactions with iron, which lead to low‐valent borylene complexes, highlighting fundamental differences in oxidation state preferences between iron and ruthenium.
ChemInform Abstract: PHOTOELECTROCHEMICAL STUDIES OF A MOLYBDENUM DISULFIDE (MOS2) ELECTRODE BY THE ROTATING RING‐DISK ELECTRODE TECHNIQUE
Authors: FUJISHIMA A. , NOGUCHI Y. , HONDA K. , LOO B. H. 
Published: April 2016

AbstractIm Vergleich zu anderen Halbleiterphotoelektroden wie CdS, ZnO und TiO2 hängen die konkurrierenden Oxidationen der verschiedenen Reduktionsmittel an der n‐MoS2‐Elektrode nicht eindeutig von ihren Redoxpotentialen ab.
ChemInform Abstract: Anisotropy und Magnetic Phase Transitions in the Rare Earth Tetraborides TbB4.
Authors: GIANDUZZO J. C. , GEORGES R. , CHEVALIER B. , ETOURNEAU J. , HAGENMULLER P. , WILL G. , SCHAEFER W. + 
Published: April 2016

AbstractZur Bestimmung der elektronischen Eigenschaften der "litelboritie (Ußq‐Typ) werden große Einkristalle von 50‐100 Ing mit Hilfe der Czochrulski und der AI‐Flux‐Mcthoden gezüchtet und magnetische sowie elektrische Messungen im Temp‐Bereich 2‐300 K bei magnetischen beldstarken D15 zu zsu Kue iangs verscnie‐ dener kristullographischer Richtungen durchgeführt.
ChemInform Abstract: EXISTENCE OF A NEW PHASE IN THE BARIUM CARBONATE‐BARIUM SULFATE SYSTEM
Authors: HAJEK B. , ONDRACEK J. , MUCK A. 
Published: April 2016

AbstractDas System BaCO3‐BaSO4 wird an aus verdünnten wäßrigen Lösungen gefällten Proben IR‐spektroskopisch, röntgenographisch, thcrmoanalytisch (TGA, DTA) und durch mikroskopische Analyse untersucht.
ChemInform Abstract: BRANCHING STRATEGY IN ORGANIC SYNTHESIS. 2. REVERSAL OF OLEFIN POLARIZATION WITH CONCOMITANT CARBON‐CARBON BOND FORMATION
Authors: TABER D. F. , SALEH S. A. 
Published: April 2016

AbstractDas Iodid (I) reagiert mit dem Allylsulfon (II) bei niederer Temperatur zum Substitutionsprodukt (III), das mit Kaliumcyanid in Gegenwart von Kronenethern das Nitril (IVa) bildet und dann durch Reduktion mit Diisobutylaluminiumhydrid in den Aldehyd (IVb) übergeführt wird.
ChemInform Abstract: Solvolytic Studies of the Highly Deactivated 1‐Aryl‐1‐(trifluoromethyhethyl Tosylates.
Authors: LIU K.‐T. , KUO M.‐Y. , SHU C.‐F. 
Published: April 2016

AbstractDie Arylderivate (I) und (II) wurden aus CFa‐CO‐Me durch Grignard‐Reaktion mit dem entsprechenden Aryl‐Mg‐Halogenid zum 2‐Aryl‐2‐propanol (Ausb. 48‐86%) und anschließende Reaktion mit PBr3 (64 und 86%) bzw. BuLi/TosCl (45A80%) dargestellt.
ChemInform Abstract: Photosensitized Oxidation of Furans. Part 3. Comparison Between Photochemically and Thermally Generated Singlet Oxygen Oxidation of 3‐Methoxycarbonyl‐2‐methyl‐5‐phenylfuran.
Authors: GRAZIANO M. L. , IESCE M. R. , CARLI B. , SCARPATI R. 
Published: April 2016

AbstractDas Furan‐endo‐peroxid (I) ergibt beim Erhitzen Gemische der Folgeprodukte (II)‐(V), letzteres im Gemisch mit (VI).
ChemInform Abstract: STUDIES ON DIAZEPINES. XV. PHOTOLYSIS OF THIENO‐, FURO‐, AND PYRROLO‐(B)PYRIDINE N‐IMIDES: FORMATION OF FUSED 1H‐1,2‐ AND 3H‐1,3‐DIAZEPINES
Authors: TSUCHIYA T. , ENKAKU M. , OKAJIMA S. 
Published: April 2016

AbstractDie aneIIierten Pyridine (I) werden mit O‐MesitylensuIfonylhydroxylamin (II) durch N‐Aminierung in die Salze (III) übergeführt, aus denen bei Acylierung die Zwitterionen (V) hergestellt werden.
ChemInform Abstract: SELECTIVE HALOGEN‐LITHIUM EXCHANGE IN SOME SECONDARY AND TERTIARY (BROMOPHENYL)ALKYL HALIDES
Authors: PARHAM W. E. , BRADSHER C. K. , REAMES D. C. 
Published: April 2016

AbstractAus den Halogeniden (I) erhält man mit Butyllithium bei niederer Temperatur die Li‐Verbindungen (II), die mit Wasser zu (III) hydrolysiert werden, während Cyclohexanon (IV) zu den spirocyclischen Ethern (V) führt.
ChemInform Abstract: SYNTHESES AND CARBON‐13 NMR SPECTRA OF TRANS, CIS‐ AND TRANS,TRANS‐NEPETALINIC ACIDS AND PHOTOCITRAL A
Authors: SAKAI T. , MORITA K. , MATSUMURA C. , SUDO A. , TSUBOI S. , TAKEDA A. 
Published: April 2016

AbstractSynthesen und NMR‐Spektren von verschiedenen Cyclopentancarbonsäuren und entsprechenden Alkoholen bzw. Aldehyden werden beschrieben.
ChemInform Abstract: Preparation of 2,5‐Dimethyl‐3‐(2‐methyl‐1‐Cyclohexenyl)‐4‐thiophenecarboxylic Acid and 2,5‐Dimethyl‐3‐(2‐methyl‐2,6‐cyelohexadienyl)‐4‐thiophenecarboxylic Acid.
Authors: SVENSSON A. , HAKANSSON R. 
Published: April 2016

AbstractDas IS‐Lithitxmderivat des Thiophens (I) wird mit Z‐Methylcyclohexzmon (II) umgesetzt und der nach der Hydrolyse anfallende tertiäre Alkohol mit TosOH zu dem Bromcyclohexylthiophen (III) dehydratisiert, Lithiiertlng des Bromderivates (III) und anschließendes Behandeln mit (′O2 liefern die erstgenannte Titelverbindtnlg (IV).
ChemInform Abstract: NEW ANTIMICROBIAL AGENTS: PREPARATION OF SUBSTITUTED PYRAZOLES AND ISOXAZOLES
Authors: MITTAL A. K. , SINGHAL O. P. 
Published: April 2016

AbstractDie durch Kupplung von Diazoniumsalzen erhaltenen substituierten 1,3‐Dicarbonyl‐ Verbindungen (I) werden mit Phenylhydrazin (II) bzw. Hydroxylamin (IV) zu Pyrazolen (III) und Isoxazolen (V) kondensiert.
ChemInform Abstract: STUDIES ON 2,1‐BENZISOXAZOLES. BEHAVIOR TOWARDS ELECTROPHILIC SUBSTITUTION AND CYCLOADDITION REACTIONS
Authors: BORUAH R. C. , SANDHU J. S. , THYAGARAJAN G. 
Published: April 2016

AbstractBei der Nitrierung der ll‐Benzisoxazole (I) entstehen die Nitroverbixtdtnlgen (II).
ChemInform Abstract: INTERACTION OF 2‐AMINO‐4‐PHENYL‐5‐ARYLAZOTHIAZOLES WITH 2‐NITRO‐, 3‐NITRO‐ AND 4‐NITROBENZALDEHYDES
Authors: JAIN R. , TYAGI S. , AGARWAL S. 
Published: April 2016

AbstractDurch [Imsctzuxlg von Amino‐zlzothiznzolcn (I) mit Nilro benzanlciehyden (II) werden die Azomethine (III) erhalten.
ChemInform Abstract: PSYCHOTROPIC AGENTS. V. SYNTHESIS OF 1,3‐DIPHENYL‐4‐(4‐SUBSTITUTED PIPERIDINYL)‐1‐BUTANONES AND RELATED COMPOUNDS
Authors: SATO M. , UCHIMARU F. 
Published: April 2016

AbstractAus den Ihityrolactonen (I) werden mit den Benzoesäureestern (II) die Chlorbutanone (III) und weiter deren Ketale (IV) hergestellt.
ChemInform Abstract: REACTION OF 1,2,3,4‐TETRAHYDROQUINAZOLIN‐4‐ONES WITH ACID ANHYDRIDE. III
Authors: YAMATO M. , HORIUCHI J. , TAKEUCHI Y. 
Published: April 2016

AbstractDie Umsetzung der aus dem o‐Aminobenzamitl (I) zugänglichen Chinazolinone (III) mit Acetanhydrid/Pyridin wird in Abhängigkeit von den Substituenten in 3‐Stellung untersucht.
ChemInform Abstract: URACIL DERIVATIVES. II. SYNTHESES AND GROWTH‐INHIBITORY ACTIVITY AGAINST L‐1210 CELLS OF 5‐(4‐SUBSTITUTED‐PHENYLTHIOMETHYL)‐6‐CARBAMOYLURACILS
Authors: OKADA J. , NAKANO K. , MIYAKE H. , YASUFUKI S. 
Published: April 2016

AbstractAus den Chlormethyluracilcarbonsäureestern (I) werden mit den Thiolaten (IIa) bzw. (IIb) die substituierten Thiomethylverbindungen (IIIa) und (IIIb) Lind weiter die Amide (IVa) und (IVb) hergestellt.
ChemInform Abstract: BLOCKING‐DEBLOCKING OF THE NITROGEN‐HYDROGEN FUNCTIONALITY OF URACIL AND ITS DERIVATIVES
Authors: KUNDU N. G. 
Published: April 2016

AbstractIn der BenzyIoxymethyl‐Gruppe wurde eine NH‐Schutzgnlppe gefunden, die unter relativ milden Bedingungen mit Trimethyliodsilan (II) abspaltbar ist.
ChemInform Abstract: POLYCONDENSED NITROGEN HETEROCYCLES. X (1A,B). 5,6,7,8‐TETRAHYDROPYRROLO(1,2‐E)(1,5)BENZODIAZOCIN‐7‐ONES. A NEW RING SYSTEM
Authors: AIELLO E. , DATTOLO G. , CIRRINCIONE G. , ALMERICO A. M. , D'ASDIA I. 
Published: April 2016

AbstractAus den Diketonen (I) entstehen mit β‐Alanin (II) die Kondensationsprodukte (III).
ChemInform Abstract: NEW METHODS AND REAGENTS IN ORGANIC SYNTHESIS. 17. TRIMETHYLSILYLDIAZOMETHANE(TMSCHN2) AS A STABLE AND SAFE SUBSTITUTE FOR HAZARDOUS DIAZOMETHANE. ITS APPLICATION TO THE ARNDT‐EISTERT SYNTHESIS
Authors: AOYAMA T. , SHIOIRI T. 
Published: April 2016

AbstractDie Herstellung des stabilen Trimethylsilyldiazomethans (II) aus dem Chlormethylsilan (I) wird beschrieben.
ChemInform Abstract: ((CH3)5C5SN(C5H5N))+: SYNTHESIS, STRUCTURE, AND BONDING RELATIONS
Authors: JUTZI P. , KOHL F. , KRUEGER C. + , WOLMERSHAEUSER G. + , HOFMANN P. , STAUFFERT P. 
Published: April 2016

AbstractDurch Uni‐ Setzung von Pentzimethyleyelopentudienylzinntritltiormethansulfonat (I) mit Pyridin gelingt es.
ChemInform Abstract: SYNTHESIS AND X‐RAY STRUCTURE OF THE BINUCLEAR COMPLEX ((MEC(CH2PET2)3)FE(μ‐CL)3FE(MEC(CH2PET2)3))BPH4.CNTDOT.CH2CL2. INTERPRETATION OF THE GEOMETRICAL AND ELECTRONIC FEATURES THROUGH A RECENT MO APPROACH FOR M2L9 COMPLEXES
Authors: BIANCHINI C. , DAPPORTO P. , MEALLI C. , MELI A. 
Published: April 2016

AbstractDas stabile Titelkation (I) entsteht bei der l zl‐molaren Umsetzung von Fetll)‐chloridhexahydrat mit 1,l.l‐Tris‐[diethylphosphinomethyll‐ethan bei Raumtemp. und wird als Tetraphenylborat in Form seines Methylenchlorid‐Monosolvuts isoliert (keine Ausb‐Angabe).
ChemInform Abstract: (TETRABENZOPORPHYRINATO)NICKEL(II) IODIDE. A DOUBLY MIXED VALENCE MOLECULAR CONDUCTOR
Authors: MARTINSEN J. , PACE L. J. , PHILLIPS T. E. , HOFFMAN B. M. , IBERS J. A. 
Published: April 2016

AbstractDie Titelverbindung erhält man durch Iod‐Oxidation des Nitlli‐Komplexes (l).
ChemInform Abstract: A FORMAL TOTAL SYNTHESIS OF FUSIDIC ACID
Authors: DAUBEN W. G. , KESSEL C. R. , KISHI M. , SOMEI M. , TADA M. , GUILLERM D. 
Published: April 2016

AbstractSelektive Ketalisierung von (I) gefolgt von Reduktion des gebildeten 3‐Mon0ketals liefert das 17β‐Hydroxyketal.
ChemInform Abstract: 4‐AMINO‐ AND 4‐HYDROXYCYCLOHEXANE‐1,1‐DICARBOXYLIC ACID PEPTIDES
Authors: SKARIC V. , MAKAREVIC J. 
Published: April 2016

AbstractIn der Annahme, daß die Einführung cyelischer Systeme in Peptide mit niedrigem Molekulargewicht eine Steigerung der biologischen Eigenschaften der Peptide bewirkt.
ChemInform Abstract: A NEW CLASS OF NITROSOUREAS. II. SYNTHESIS AND ANTITUMOR ACTIVITY OF 1‐(2‐CHLOROETHYL)‐3,3‐DISUBSTITUTED‐1‐NITROSOUREAS HAVING A GLUCOPYRANOSYL, MANNOPYRANOSYL OR GALACTOPYRANOSYL MOIETY
Authors: TSUJIHARA K. , OZEKI M. , MORIKAWA T. , TAGA N. , MIYAZAKI M. , KAWAMORI M. , ARAI Y. 
Published: April 2016

AbstractDie durch Glucose, Mannose oder Galaktose substituierten Chlorethyl‐nitrosmharnstoffderivate (IV) werden durch Nitrosierung der Chlorethylharnstoffderivate (III) hergestellt, die aus den Glykosylaminen (I) zugänglich sind.
ChemInform Abstract: CRYSTAL STRUCTURE OF A NEW CESIUM MANGANESE VANADIUM OXIDE, CS3MN3V4O16
Authors: LE PAGE Y. , STROBEL P. 
Published: April 2016

AbstractDie elektrolytisch aus einer Salzschmelze einkristallin erhaltene Titelverbindung kristallisiert in der Raumgruppe Pl mit Z=1.
ChemInform Abstract: THE ELECTROCHEMICAL AND PHOTOELECTROCHEMICAL CHARACTERISTICS OF N‐TYPE SODIUM NIOBATE
Authors: MCCANN J. F. , KHAN A. 
Published: April 2016

Abstractn‐Leitendes NaNbOg kann als stabile Anode sowohl in sauren (1 M H2SO4) als auch alkalischen Medien (1 M NaOH) in einer photoelektrochemischen Zelle verwendet werden (negativere Flachbandpotentiale als das 2 H+/H2‐Redoxpotential).
ChemInform Abstract: CHEMICAL AND PHYSICAL PROPERTIES OF SOME XENON COMPOUNDS
Authors: HUSTON J. L. 
Published: April 2016

AbstractDie gebräuchlichen präparativen Reaktionen für eine Reihe von Xenonverbindungen lassen sich im Sinne einer Säure‐Base‐Chemie (Oxidakzeptoren‐Oxiddonatoren) systematisieren.