bluuebunny/crossref_metadata_2025_split huggingface dataset:
GV/cm scale laser-magnetic resonant acceleration in vacuum
Authors: Zhang Y. , Jiao J.-L. , Zhang B. , Zhang Z.-M. , Gu Y.-Q. 
Published: August 2017

AbstractResonant acceleration of electrons by a laser in the background of an extra longitudinal magnetic field is investigated analytically and numerically. The resonant condition is independent of laser intensity, and when satisfied, the energy gain is proportional to $a_0^2 $ and the square of phase difference. This process is mainly limited by the magnitude and spatial size of the extra magnetic field. Under the laboratory conditions, simulation results show that a monoenergetic and collimated electron bunch can still be obtained in ~ GV/cm scale, which sheds a light on the vacuum table-top laser-driven electron accelerators.
Centralizing Trends and Pollution Law Enforcement in China
Authors: van Rooij Benjamin , Zhu Qiaoqiao , Na Li , Qiliang Wang 
Published: August 2017

AbstractThis article analyses centralizing trends that may be able to reduce the negative influence of local protectionism on environmental law enforcement in China. The article finds that as centralizing trends unfolded, enforcement over time has become stricter and more frequent, however with only minor effects in reducing pollution. Moreover it finds a situation of uneven enforcement with richer and more urbanized areas having much stronger and more frequent enforcement than inland areas. Centralizing trends may thus have spurred stronger enforcement, but concurrently allowed for an uneven enforcement. At the same time, the article finds a continued local influence, keeping enforcement too weak to have much effect in reducing pollution and allowing for local interests to shape enforcement into unequal outcomes.
Relationship between apoptosis and survival molecules in human cumulus cells as markers of oocyte competence
Authors: Bosco Liana , Chiarelli Roberto , Roccheri Maria Carmela , Matranga Domenica , Ruvolo Giovanni 
Published: August 2017

SummaryTo select from a single patient the best oocytes able to reach the blastocyst stage, we searched for valuable markers for oocytes competence. We evaluated the DNA fragmentation index (DFI) and the level of some survival molecules, such as AKT, pAKT and pERK1/2, in individual cumulus cell–oocyte complexes (COC). The study included normo-responder women. The average age of the patients was 34.3. DFI in cumulus cells was evaluated using the terminal deoxynucleotidyl transferase (TdT) dUTP nick-end labelling (TUNEL) assayin situ. AKT, pAKT and pERK1/2 were measured by immunological assay and densitometric analysis of fluorescent signals using NIS-Elements BR 3.10 image software. Statistical analysis was performed using STATA SE/14.1. The study focused on 53 patients involved after informed consent. Out of 255 MII oocytes, 197 were fertilized and the derived embryos had the following evolution: 117 completed the development to blastocyst and were transferred to uterus; 57 were vitrified at the blastocyst stage; and 23 were arrested duringin vitroculture at different stages of cleavage. We found a significant statistical difference between the DFI of cumulus cells of the arrested embryos and the transferred blastocysts (P= 0.004), confirming that DFI could be considered as a valuable marker of oocyte competence. In addition, the pAKT/DFI ratio was higher in cumulus cells of oocytes able to produce blastocysts, indicating that DFI is significantly lower when pAKT is higher (P= 0.043). This study demonstrates for the first time that the relationship between apoptosis and survival molecules can be used as a marker to select the best oocytes.
Reconstruction of Laser-Induced Surface Topography from Electron Backscatter Diffraction Patterns
Authors: Callahan Patrick G. , Echlin McLean P. , Pollock Tresa M. , De Graef Marc 
Published: August 2017

AbstractWe demonstrate that the surface topography of a sample can be reconstructed from electron backscatter diffraction (EBSD) patterns collected with a commercial EBSD system. This technique combines the location of the maximum background intensity with a correction from Monte Carlo simulations to determine the local surface normals at each point in an EBSD scan. A surface height map is then reconstructed from the local surface normals. In this study, a Ni sample was machined with a femtosecond laser, which causes the formation of a laser-induced periodic surface structure (LIPSS). The topography of the LIPSS was analyzed using atomic force microscopy (AFM) and reconstructions from EBSD patterns collected at 5 and 20 kV. The LIPSS consisted of a combination of low frequency waviness due to curtaining and high frequency ridges. The morphology of the reconstructed low frequency waviness and high frequency ridges matched the AFM data. The reconstruction technique does not require any modification to existing EBSD systems and so can be particularly useful for measuring topography and its evolution duringin situexperiments.
In Situ Thermal Annealing Transmission Electron Microscopy (TEM) Investigation of III/V Semiconductor Heterostructures Using a Setup for Safe Usage of Toxic and Pyrophoric Gases
Authors: Straubinger Rainer , Beyer Andreas , Ochs Thomas , Stolz Wolfgang , Volz Kerstin 
Published: August 2017

AbstractIn this study we compare two thermal annealing series of III/V semiconductor heterostructures on Si, where during the first series nitrogen is present in the in situ holder. The second, comparative, measurement is done in a tertiarybutylphosphine (TBP) environment. The sample annealed in a TBP environment shows favorable thermal stability up to 500°C compared to the unstabilized sample, which begins to degrade at less than 300°C. Evaporation of P from the material is tracked qualitatively by measuring the thickness of the sample during thermal annealing with and without stabilization. Finally, we investigate the in situ thermal annealing processes at atomic resolution. Here it is possible to study phase separation as well as the diffusion of As from a Ga(NAsP) quantum well in the surrounding GaP material during thermal annealing. To make these investigations possible we developed an extension for our in situ transmission electron microscopy setup for the safe usage of toxic and pyrophoric III/V semiconductor precursors. A commercially available gas cell and gas supply system were expanded with a gas mixing system, an appropriate toxic gas monitoring system and a gas scrubbing system. These components allow in situ studies of semiconductor growth and annealing under the purity conditions required for these materials.
Planetary nebulae as kinematic tracers of galaxy stellar halos
Authors: Coccato Lodovico 
Published: August 2017

AbstractThe kinematic and dynamical properties of galaxy stellar halos are difficult to measure because of the faint surface brightness that characterizes these regions. Spiral galaxies can be probed using the radio Hiemission; on the contrary, early-type galaxies contain less gas, therefore alternative kinematic tracers need to be used. Planetary nebulae (PNe) can be easily detected far out in the halo thanks to their bright emission lines. It is therefore possible to map the halo kinematics also in early-type galaxies, typically out to 5 effective radii or beyond. Thanks to the recent spectroscopic surveys targeting extra-galactic PNe, we can now rely on a few tens of galaxies where the kinematics of the stellar halos are measured. Here, I will review the main results obtained in this field in the last decades.
3He Abundances in Planetary Nebulae
Authors: Guzman-Ramirez Lizette 
Published: August 2017

AbstractDetermination of the 3He isotope is important to many fields of astrophysics, including stellar evolution, chemical evolution, and cosmology. The isotope is produced in stars which evolve through the planetary nebula phase. Planetary nebulae are the final evolutionary phase of low- and intermediate-mass stars, where the extensive mass lost by the star on the asymptotic giant branch is ionised by the emerging white dwarf. This ejecta quickly disperses and merges with the surrounding ISM. 3He abundances in planetary nebulae have been derived from the hyperfine transition of the ionised 3He, 3He+, at the radio rest frequency 8.665 GHz. 3He abundances in PNe can help test models of the chemical evolution of the Galaxy. Many hours have been put into trying to detect this line, using telescopes like the Effelsberg 100m dish of the Max Planck Institute for Radio Astronomy, the National Radio Astronomy Observatory (NRAO) 140-foot telescope, the NRAO Very Large Array, the Arecibo antenna, the Green Bank Telescope, and only just recently, the Deep Space Station 63 antenna from the Madrid Deep Space Communications Complex.
The PN.S ETG survey
Authors: Arnaboldi M. , Pulsoni C. , Gerhard O. ,   PN.S Consortium
Published: August 2017

AbstractWe have analyzed the velocity fields in the halos of thirty-three early-type galaxies (ETGs) with planetary nebulae (PNs) as tracers, reaching radii of up to ~8Re. The sample comprises twenty-five galaxies from the Planetary Nebulae Spectrograph (PN.S) ETG survey and eight further galaxies with extended PN velocity data from the literature and new Counter-Dispersed imaging observations. The catalogues from these thirty-three ETGs provide astrometric positions and heliocentric line-of-sight velocities for a total of 8354 extragalactic PNs. All these catalogues are treated homogeneously for the identification of kinematic outliers and the separation between main galaxy/satellites in each galaxy field-of-view. We discuss the rotation velocities, velocity dispersion profiles and radial trends of the specific angular momentum, separating between slow rotators and fast rotators. We compare the properties of the V/σ(R) and σ(R) profiles with predictions of 2D velocity fields from hydro-dynamical cosmological simulations. We briefly mention the possible origin of the quasi-Keplerian steeply decreasing profile galaxies which encompasses about one fourth of the current sample.
The kinematics of the nebular shells around low mass progenitors of PNe with low metallicity
Authors: Pereyra Margarita , López José Alberto , Richer Michael G. 
Published: August 2017

AbstractIn the past few years we provided strong observational support for theoretical studies regarding the internal kinematics of Planetary Nebulae (PNe). A total of 257 objects segregated by different galactic populations were analized. Based upon spatially-resolved, long-slit, echelle spectroscopy drawn from the San Pedro Mártir Kinematic Catalogue of PNe†, we characterized the kinematics of PNe shells measuring their global expansion velocities. We present here a brief summary of these observational results, with a focus on our most recent study of about 26 PNe with low metallicity that appear to derive from progenitor stars of the lowest masses (including the halo PNe population). Low expansion velocities were found for these nebulae, less than 20 km s−1, which are most likely associated with a weak central star wind driving the kinematics of the nebular shell in this particular population.
Exploring the transition into an asymmetric planetary nabulae
Authors: Cárdenas Mónica W. Blanco , Vázquez Roberto , Kaeufl Hans Ulrich , Gómez-Muñoz Marco A. , Guillén Pedro F. , Guerrero Martín A. , Miranda Luis F. 
Published: August 2017

AbstractWe present studies using different observational techniques, along different frequencies, aiming to resolve and investigate jets, outflows, as well as compact and innermost regions of asymmetric planetary nebulae (PNe) and objects in transition to PN. All the information gathered allow us to explore the kinematics and other important properties of the structures that play a crucial role in the shaping of complex PNe morphologies, in particular, we explore the role of disks/tori as collimating engine of extreme axisymmetric PNe.
Temperature effects on the infrared spectrum of molecules in planetary nebulae
Authors: Chen Tao , Mackie Cameron , Tielens Alexander G. G. M. 
Published: August 2017

AbstractIn this work, we utilize a method based on Wang-Landau Monte Carlo sampling for studying the temperature effects of astrophysically relavant molecules. Anharmonic effects, e.g., resonances, overtones, and combination bands, are fully incoportated in this method. The calculated infrared (IR) spectra are consistent with the experimental data measured by National Institute of Standards and Technology (NIST).
Characterizing global expansion evolution of the ionized matter in planetary nebulae
Authors: López J. A. , Richer M. G. , Pereyra M. , García-Díaz M. T. 
Published: August 2017

AbstractBulk outflow or global expansion velocities are presented for a large number of planetary nebulae (PNe) that span a wide range of evolutionary stages and different stellar populations. The sample comprises 133 PNe from the Galactic bulge, 100 mature and highly evolved PNe from the disk, 11 PNe from the Galactic halo and 15 PNe with very low central star masses and low metallicities, for a total of 259 PNe. These results reveal from a statistical perspective the kinematic evolution of the expansion velocities of PNe in relation to changing characteristics of the central star’s wind and ionizing luminosity and as a function of the evolutionary rate determined by the central (CS) mass. The large number of PNe utilized in this work for each group of PNe under study and the homogeneity of the data provide for the first time a solid benchmark form observations for model predictions, as has been described by López et al. (2016).
Search for binary central stars of the Magellanic Clouds PNe
Authors: Gładkowski Marcin , Hajduk Marcin , Soszyński Igor 
Published: August 2017

AbstractThe Optical Gravitational Experiment (OGLE) was effectively used in discovering binary central stars of planetary nebulae (CSPNe). About 50 binary CSPNe have been hitherto identified in the Galaxy, almost half of them were detected in the OGLE database. We used the OGLE data to search for binary CSPNe in the Magellanic Clouds. We also searched for PNe mimics and removed them from the PNe sample. Here, we present results of the photometric analysis for Small Magellanic Cloud (SMC) and our progress on search of binary central stars in the Large Magellanic Cloud (LMC). So far, we have discovered one binary central star of the PN beyond the Milky Way, which is located in the Small Magellanic Cloud.
Emission Lines of Northern Planetary Nebulae
Authors: Aksaker Nazim , Yerli Sinan K. , Kızıloğlu Ümit , Atalay Betül 
Published: August 2017

AbstractIn this work, we present results of long slit spectrophotometric emission line flux observations of selected planetary nebulae (PNe). We have measured absolute fluxes and equivalent widths (EW) of all observable emission lines. In addition to these observations, electron temperatures (Te), densities (Ne), and chemical abundances were also calculated. The main purpose of this work is to fill the gaps in emission line flux standards for the northern hemisphere. It is expected that the measured fluxes would be used as standard data set for further photometric and spectrometric measurements of HII regions, supernova remnants etc.
Post-AGB binaries as tracers of stellar evolution.
Authors: Van Winckel Hans 
Published: August 2017

AbstractIn this contribution the focus is on post-AGB binaries. It is now well established that these are often surrounded by stable long-lived circumbinary discs of gas and dust. Here we introduce our monitoring programme with our high-resolution spectrograph HERMES mounted on the 1.2m Mercator telescope. We illustrate the use of time-series high-resolution spectra and show that jets observed in many systems are launched at the location of the companion. The jet is likely originating from a circum-companion accretion disc. The link of these systems to some PNe relies on the detection of similar orbits and hence wide spectroscopic orbits among central stars of PNe. The conclusion is that Keplerian discs as well as circum-companion discs are fundamental to understanding the properties and evolution of these interacting evolved binaries.
Clinical-grade human umbilical cord-derived mesenchymal stem cells reverse cognitive aging via improving synaptic plasticity and endogenous neurogenesis
Authors: Cao Ning , Liao Tuling , Liu Jiajing , Fan Zeng , Zeng Quan , Zhou Junnian , Pei Haiyun , Xi Jiafei , He Lijuan , Chen Lin , Nan Xue , Jia Yali , Yue Wen , Pei Xuetao 
Published: August 2017

AbstractCognitive aging is a leading public health concern with the increasing aging population, but there is still lack of specific interventions directed against it. Recent studies have shown that cognitive function is intimately affected by systemic milieu in aging brain, and improvement of systemic environment in aging brain may be a promising approach for rejuvenating cognitive aging. Here, we sought to study the intervention effects of clinical-grade human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) on cognitive aging in a murine model of aging. The conventional aging model in mice induced by d-galactose (d-gal) was employed here. Mice received once every two weeks intraperitoneal administration of hUC-MSCs. After 3 months of systematical regulation of hUC-MSCs, the hippocampal-dependent learning and memory ability was effectively improved in aged mice, and the synaptic plasticity was remarkably enhanced in CA1 area of the aged hippocampus; moreover, the neurobiological substrates that could impact on the function of hippocampal circuits were recovered in the aged hippocampus reflecting in: dendritic spine density enhanced, neural sheath and cytoskeleton restored, and postsynaptic density area increased. In addition, the activation of the endogenic neurogenesis which is beneficial to stabilize the neural network in hippocampus was observed after hUC-MSCs transplantation. Furthermore, we demonstrated that beneficial effects of systematical regulation of hUC-MSCs could be mediated by activation of mitogen-activated protein kinase (MAPK)-ERK-CREB signaling pathway in the aged hippocampus. Our study provides the first evidence that hUC-MSCs, which have the capacity of systematically regulating the aging brain, may be a potential intervention for cognitive aging.
P53-dependent downregulation of hTERT protein expression and telomerase activity induces senescence in lung cancer cells as a result of pterostilbene treatment
Authors: Chen Rong-Jane , Wu Pei-Hsuan , Ho Chi-Tang , Way Tzong-Der , Pan Min-Hsiung , Chen Hsiu-Min , Ho Yuan-Soon , Wang Ying-Jan 
Published: August 2017

AbstractCellular senescence is characterized by permanent cell cycle arrest, triggered by a variety of stresses, such as telomerase inhibition, and it is recognized as a tumor-suppressor mechanism. In recent years, telomerase has become an important therapeutic target in several cancers; inhibition of telomerase can induce senescence via the DNA damage response (DDR). Pterostilbene (PT), a dimethyl ether analog of resveratrol, possesses a variety of biological functions, including anticancer effects; however, the molecular mechanisms underlying these effects are not fully understood. In this study, we investigated the possible mechanisms of PT-induced senescence through telomerase inhibition in human non-small cell lung cancer cells and delineated the role of p53 in senescence. The results indicated that PT-induced senescence is characterized by a flattened morphology, positive staining for senescence-associated-β galactosidase activity, and the formation of senescence-associated heterochromatic foci. Telomerase activity and protein expression was significantly decreased in H460 (p53 wild type) cells compared with H1299 (p53 null) cells and p53 knockdown H460 cells (H460-p53-). A more detailed mechanistic study revealed that PT-induced senescence partially occurred via a p53-dependent mechanism, triggering inhibition of telomerase activity and protein expression, and leading to the DDR, S phase arrest and, finally, cellular senescence. This study is the first to explore the novel anticancer mechanism of PT senescence induction via the inhibition of telomerase in lung cancer cells.
PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)
Authors: Kranz Philip , Neumann Fabian , Wolf Alexandra , Classen Fabian , Pompsch Mosche , Ocklenburg Tobias , Baumann Jennifer , Janke Kirsten , Baumann Melanie , Goepelt Kirsten , Riffkin Helena , Metzen Eric , Brockmeier Ulf 
Published: August 2017

AbstractEndoplasmic reticulum (ER) stress leads to activation of the unfolded protein response (UPR) that results in transient suppression of protein translation to allow recovery but leads to cell death when stress cannot be resolved. Central to initiation of the UPR is the activation of the ER transmembrane kinase protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK). Here we report that the thiol oxidoreductase ERp57 and protein disulfide isomerase-A1 (PDI), which belong to the same family of luminal ER oxidoreductases, have strikingly opposing roles in the regulation of PERK function. In HCT116 colon carcinoma cells, lentiviral depletion of ERp57 resulted in oxidation of PDI and activation of PERK, whereas depletion or chemical inhibition of PDI reduced PERK signaling and sensitized the cancer cells to hypoxia and ER stress. We conclude that oxidized PDI acts as a PERK activator, whereas ERp57 keeps PDI in a reduced state in the absence of ER stress. Thus, our study defines a new interface between metabolic redox signaling and PERK-dependent activation of the UPR and has the potential to influence future cancer therapies that target PERK signaling.
Loss of PHD3 in myeloid cells dampens the inflammatory response and fibrosis after hind-limb ischemia
Authors: Beneke Angelika , Guentsch Annemarie , Hillemann Annette , Zieseniss Anke , Swain Lija , Katschinski Dörthe M 
Published: August 2017

AbstractMacrophages are essential for the inflammatory response after an ischemic insult and thereby influence tissue recovery. For the oxygen sensing prolyl-4-hydroxylase domain enzyme (PHD) 2 a clear impact on the macrophage-mediated arteriogenic response after hind-limb ischemia has been demonstrated previously, which involves fine tuning a M2-like macrophage population. To analyze the role of PHD3 in macrophages, we performed hind-limb ischemia (ligation and excision of the femoral artery) in myeloid-specific PHD3 knockout mice (PHD3−/−) and analyzed the inflammatory cell invasion, reperfusion recovery and fibrosis in the ischemic muscle post-surgery. In contrast to PHD2, reperfusion recovery and angiogenesis was unaltered in PHD3−/−compared to WT mice. Macrophages from PHD3−/−mice showed, however, a dampened inflammatory reaction in the affected skeletal muscle tissues compared to WT controls. This was associated with a decrease in fibrosis and an anti-inflammatory phenotype of the PHD3−/−macrophages, as well as decreased expression of Cyp2s1 and increased PGE2-secretion, which could be mimicked by PHD3−/−bone marrow-derived macrophages in serum starvation.