bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of pharmacist-led interventions in optimising prescribing in older adults in primary care: A systematic review
Authors: Riordan David O , Walsh Kieran A , Galvin Rose , Sinnott Carol , Kearney Patricia M , Byrne Stephen 
Published: June 2016

Objective: To evaluate studies of pharmacist-led interventions on potentially inappropriate prescribing among community-dwelling older adults receiving primary care to identify the components of a successful intervention. Data sources: An electronic search of the literature was conducted using the following databases from inception to December 2015: PubMed, Embase, Cumulative Index to Nursing and Allied Health Literature, MEDLINE (through Ovid), Trip, Centre for Reviews and Dissemination databases, Cochrane Database of Systematic Reviews, ISI Web of Science, ScienceDirect, ClinicalTrials.gov , metaRegister of Controlled Trials, ProQuest Dissertations & Theses Database (Theses in Great Britain, Ireland and North America). Review methods: Studies were included if they were randomised controlled trials or quasi-randomised studies involving a pharmacist-led intervention compared to usual/routine care which aimed to reduce potentially inappropriate prescribing in older adults in primary care. Methodological quality of the included studies was independently assessed. Results: A comprehensive literature search was conducted which identified 2193 studies following removal of duplicates. Five studies met the inclusion criteria. Four studies involved a pharmacist conducting a medication review and providing feedback to patients or their family physician. One randomised controlled trial evaluated the effect of a computerised tool that alerted pharmacists when elderly patients were newly prescribed potentially inappropriate medications. Four studies were associated with an improvement in prescribing appropriateness. Conclusion: Overall, this review demonstrates that pharmacist-led interventions may improve prescribing appropriateness in community-dwelling older adults. However, the quality of evidence is low. The role of a pharmacist working as part of a multidisciplinary primary care team requires further investigation to optimise prescribing in this group of patients.
Delivering a one-stop, integrated, and patient-centered service for patients with rheumatic diseases
Authors: Väre Paula , Nikiphorou Elena , Hannonen Pekka , Sokka Tuulikki 
Published: June 2016

Objective: To describe a one-stop, integrated rheumatology service and assess patient satisfaction. Methods: A descriptive report and patient satisfaction survey of a rheumatology clinic model first developed in 1996 to enhance the patient “journey” through rheumatology services. A patient-satisfaction survey over a 3-week period assessed several aspects of care including quality of services, consultations, and patient education. Results: All referrals are screened by a rheumatologist to pre-schedule laboratory/radiology/other tests for the visit. Upon arrival to the clinic, patients check-in at an electronic desk, and then complete the electronic GoTreatIT monitoring system which assesses patient-reported outcomes. The patient is reviewed by a doctor in a 30- to 60-min consultation, and then by a nurse (for diagnosis/treatment education, vaccinations). An ultrasound machine and capillaroscopy are available for use in the clinic. Patients can be scheduled on the same day to see a nutritionist, physiotherapist, or other heath professionals as necessary. An “early-rheumatoid arthritis treatment path” is available to ensure early, intensive treatment. A patient satisfaction survey revealed high rating of the overall service (90.6/100). None of the patients felt that they lacked education on their disease or medication. Only 6% of the respondents gave negative feedback, reasons including feeling overwhelmed with information or not being given a cause for their symptoms. The multi-disciplinary approach was highly valued and only 3% would rather see a doctor and nurse on separate days. Conclusion: The specific clinic model provides an ideal setting for a one-stop service, avoiding unnecessary visits, collecting patient data, and enhancing the patient experience and journey through the system. Where possible, the specific clinic model could be used or adapted to build similar models in other rheumatology departments. The clinic model could also form the basis for services in other specialties dealing with chronic conditions.
Validity of the Samsung Phone S Health application for assessing steps and energy expenditure during walking and running: Does phone placement matter?
Authors: Johnson Marquell , Turek Jillian , Dornfeld Chelsea , Drews Jennifer , Hansen Nicole 
Published: June 2016

Background The emergence of mHealth and the utilization of smartphones in physical activity interventions warrant a closer examination of validity evidence for such technology. This study examined the validity of the Samsung S Health application in measuring steps and energy expenditure. Methods Twenty-nine participants (mean age 21.69 ± 1.63) participated in the study. Participants carried a Samsung smartphone in their non-dominant hand and right pocket while walking around a 200-meter track and running on a treadmill at 2.24 m∙s−1. Steps and energy expenditure from the S Health app were compared with StepWatch 3 Step Activity Monitor steps and indirect calorimetry. Results No significant differences between S Health estimated steps and energy expenditure during walking and their respective criterion measures, regardless of placement. There was also no significant difference between S Health estimated steps and the criterion measure during treadmill running, regardless of placement. There was significant differences between S Health estimated energy expenditure and the criterion during treadmill running for both placements (both p < 0.001). Conclusions The S Health application measures steps and energy expenditure accurately during self-selected pace walking regardless of placement. Placement of the phone impacts the S Health application accuracy in measuring physical activity variables during treadmill running.
Pitch Characteristics Before Ulnar Collateral Ligament Reconstruction in Major League Pitchers Compared With Age-Matched Controls
Authors: Prodromo John , Patel Nimit , Kumar Neil , Denehy Kevin , Tabb Loni Philip , Tom James 
Published: June 2016

Background: Ulnar collateral ligament reconstruction (UCLR) is commonly performed in Major League Baseball (MLB) pitchers, but little is known about the preoperative pitch type and velocity characteristics of pitchers who go on to undergo UCLR. Hypothesis: Pitchers who required UCLR have thrown a greater percentage of fastballs and have greater pitch velocities compared with age-matched controls in the season before injury. Study Design: Case-control study; Level of evidence, 3. Methods: MLB pitchers active during the 2002 to 2015 seasons were included. The UCLR group consisted of MLB pitchers who received UCLR between 2003 and 2015, utilizing the season before surgery (2002-2014) for analysis. The control group comprised age-matched controls of the same season. Players who pitched less than 20 innings in the season before surgery were excluded. Pitch types were recorded as percentage of total pitches thrown. Pitch velocities were recorded for each pitch type. Pitch type and pitch velocities during preoperative seasons for UCLR pitchers were compared with age-matched controls using univariate and multivariate models. Results: A total of 114 cases that went on to UCLR and 3780 controls were included in the study. Pitchers who went on to UCLR appear to have greater fastball, slider, curveball, changeup, and split-fingered fastball velocities; there were no significant differences in pitch selection between the 2 groups. Conclusion: In the season before surgery, MLB pitchers who underwent UCLR demonstrated greater fastball, slider, curveball, changeup, and split-fingered fastball velocities, with no significant difference in pitch type.
The Economic Returns to Hospital Admitting Privileges
Authors: Rizzo John A. , Goddeeris John H. 
Published: June 2016

Legal suits contesting the denial or termination of hospital staff privileges are the most common antitrust cases involving medical markets. There is, however, very little evidence about the economic implications for the physicians of having staff privileges. Using a nationally representative sample of self-employed physicians from 1992, this article presents estimates of the effects of hospital admitting privileges on physician earnings.
The results indicate that for nonprimary care specialists with few admitting privileges, gaining an additional privilege increases earnings. This effect diminishes as the number of admitting privileges increases, however, and there are no economic gains beyond having three to four admitting privileges. Among primary care physicians, we detect no statistically significant effect of hospital admitting privileges on earnings. With the growing emphasis on managed care, physicians are being scrutinized both in terms of the quality of care they deliver and their impact on the economic performance of hospitals and managed care organizations. This suggests that the frequency of lawsuits involving the denial or rescission of medical staff privileges may assume even greater importance.
Dictyostelium EHD associates with Dynamin and participates in phagosome maturation
Authors: Gueho Aurélie , Bosmani Cristina , Gopaldass Navin , Molle Virginie , Soldati Thierry , Letourneur François 
Published: June 2016

ABSTRACT
Proteins that contain Eps15 homology domains (EHDs) in their C-terminus are newly identified key regulators of endosomal membrane trafficking. Here, we show that D. discoideum contains a single EHD protein (referred to as EHD) that localizes to endosomal compartments and newly formed phagosomes. We provide the first evidence that EHD regulates phagosome maturation. Deletion of EHD results in defects in intraphagosomal proteolysis and acidification. These defects are linked to early delivery of lysosomal enzymes and fast retrieval of the vacuolar H+-ATPase in maturing phagosomes. We also demonstrate that EHD physically interacts with DymA. Our results indicate that EHD and DymA can associate independently with endomembranes, and yet they share identical kinetics in recruitment to phagosomes and release during phagosome maturation. Functional analysis of ehd−, dymA− and double dymA−ehd− knockout strains indicate that DymA and EHD play non-redundant and independent functions in phagosome maturation. Finally, we show that the absence of EHD leads to increased tubulation of endosomes, indicating that EHD participates in the scission of endosomal tubules, as reported for DymA.
A Metal-Organic Framework Containing Arsenic Atoms with a Free Lone Pair
Authors: Ishidoshiro Makoto , Imoto Hiroaki , Naka Kensuke 
Published: June 2016

Abstract
A metal-organic framework (MOF) was constructed based on a 1,4-dihydro-1,4-diarsinine (DHDA) tetracarboxylic acid ligand, which was newly synthesized via hydrolysis of DHDA tetramethyl tetracarboxylate. The lone pairs of the arsenic atoms were not involved in the construction of the MOF. Notably, the preparation procedure of the MOF was performed under ambient atmosphere without any protecting groups, while inert atmosphere is required for incorporating trivalent phosphorus atoms.
Editorial
Authors: Λιοναράκης Αντώνης 
Published: June 2016

Κίνδυνος αποδόμησης της πιο δημοκρατικής ακαδημαϊκής καινοτομίας που υπήρξε ποτέ στην Ελλάδα: του Ελληνικού Ανοικτού Πανεπιστημίου Η αφορμή για αυτό το κείμενο απορρέει από τις ανησυχίες και τους προβληματισμούς που συζητιούνται, κυρίως το τελευταίο διάστημα, στους ακαδημαϊκούς, αλλά και πολιτικούς κύκλους για το Ανοικτό Πανεπιστήμιο. Όχι στους δημοσιογραφικούς, μιας και οι δημοσιογραφικές επεμβάσεις στο αντικείμενο εδώ και πολλά χρόνια έχουν αποδειχθεί ανακριβείς και αναξιόπιστες. Το 1997, όταν ψηφίστηκε ο νόμος για το ΕΑΠ στην Ελληνική βουλή, η μοναδική συζήτηση και διάλογος που έγινε, ήταν για την έδρα του ιδρύματος και ποια πόλη θα την είχε. Καμία συζήτηση δεν έγινε ποτέ επί της ουσίας περί της καινοτομίας και των ιδιαιτεροτήτων του. Δυστυχώς, αυτή η αντίληψη συνεχίστηκε και αργότερα πιο γενικευμένη και καθόρισε σε ένα βαθμό τη στρατηγική των προβληματισμών των υπευθύνων.
Aneurysmen des venösen Systems
Authors: Noppeney T. , Noppeney J. 
Published: June 2016

SummaryOverall, aneurysms of the venous system constitute a rare disease. Up to March 2016, 1,199 venous aneurysms at various locations had been reported in the literature. The most common were aneurysms of the extrahepatic portal vein (n=247), followed by popliteal venous aneurysms (n=223) and, in third place, aneurysms of the internal or external jugular vein (n=143). Venous aneurysms are not usually diagnosed until they have become symptomatic or have led to complications, such as thrombosis and/or pulmonary embolism. First-line treatment of symptomatic aneurysms is resection of the aneurysm and reconstruction of the vein using either direct suture or end-to-end anastomosis, depending on the location. Endovenous repairs have also been described in the literature. Venous aneurysms of the superficial venous system can usually be excised and the vein ligated. Long-term anticoagulation is reserved for isolated cases with thrombotic occlusion and recurrent pulmonary embolisms.
Venous intervention in chronic venous ulcer treatment and recurrence avoidance
Authors: Morrison N. 
Published: June 2016

SummaryIn this brief overview I will progress from superficial venous intervention for venous leg ulcers (VLU) to perforator intervention and finally to deep venous intervention. But first there are a number of concepts that must be accepted. We know that 70 % of patients with leg ulcers have a venous component (1), and in at least 40 % of those patients, ulcers will be caused by superficial venous insufficiency alone or in combination with perforator incompetence (2). Such patients will likely benefit from treatment of their superficial venous disease.One of the most important but often overlooked factors in venous ulcers is calf pump failure. Simka has reported that 45 % of patients with venous ulcers have calf pump failure (3).Thorough duplex evaluation of the venous leg ulcer patient is paramount for accurate diagnosis, the differentiation between arterial and venous components (purely arterial, venous, or mixed etiology), and the obstructive and/or incompetent nature and location of venous lesions. In obstructive venous lesions the degree of obstruction as well as how proximal the lesion extends must be known. For venous insufficiency the location (deep and/or superficial venous system) and the extent (segmental or axial) will help determine how much the incompetence contributes to the overall ulcer condition, and what lesions can be safely treated.
Choosing one name for pleomorphic fungi: The example of Aspergillus versus Eurotium, Neosartorya and Emericella
Authors: Taylor John W. , Göker Markus , Pitt John I. 
Published: June 2016

AbstractWith the termination of dual nomenclature, each fungus may have only one name. Now mycologists must choose between genus names formerly applied to taxa with either asexual or sexual reproductive modes, a choice that often influences the breadth of genotypic and phenotypic diversity in a genus, and even its monophyly. We use the asexual genus Aspergillus to examine the problems involved in such choices because (a) 11 sexual generic names are associated with it and (b) phenotypic variation and genetic divergence within sexual genera are low but between sexual genera are high. As a result, in the case of Aspergillus, applying the asexual name to the many sexual genera masks information now conveyed by the genus names and would lead to taxonomic inconsistency in the Eurotiales because this large Aspergillus would then embrace more genetic divergence than neighboring clades comprised of two or more genera. Two proposals have been published concerning this problem as it relates to Aspergillus: one advocates a broad concept, referred to here as "Wide Aspergillus", which embraces as many Aspergillus species as possible while maintaining Penicillium as a separate genus; the other, referred to here as "Narrow Aspergillus", preserves this genus for a much smaller group of closely related species and retains many of the sexual genera. Phylogenetic analyses detailed here show that, to be monophyletic, Wide Aspergillus must embrace several genera morphologically discordant with Aspergillus, including Penicillium, Phialosimplex and Polypaecilum. Likelihood ratio tests reject a Wide Aspergillus that excludes Phialosimplex and Polypaecilum. Phylogenetic Rank Boundary Optimization, which employs the genetic divergence measure, maximum subtree height, to assess inconsistency in the ranking of genera and species, shows that Narrow Aspergillus provides a more consistent taxonomy than Wide Aspergillus. Adopting Narrow Aspergillus and retaining sexual names instead of adopting Wide Aspergillus will result in genera that convey precise morphological and physiological information, that are monophyletic, and that are taxonomically consistent.
Several aspects of the use of Historical-graphical approach in the training course «Tecnology of inbound tourism»
Authors: Афанасьев Олег , Afanasiev Oleg 
Published: June 2016

The article is devoted to the use of the principles of historical-graphical approach in vocational education on the
direction «Tourism». On the base of developed practical training devoted to the historical-graphical analysis of
the sources of the XIII–XIX centuries, they examine the historical process of the formation of neutral or negative
images of our country at the Europeans. In modern conditions it has a direct impact on the demand and interest in
tourist trips to Russia. The article proposes and researches in detail the mechanisms of formation of tourist image of
the country in two forms – subjective and objective. It’s noted that the the image of a country forming even without
a direct visit/ And this image can be viewed as subjective, and potentially to be attractive (attractive), neutral, or
repulsive (repellent). Historical-graphical practice during the practical training on discipline «Technology of the
inbound tourism» shows the formation of mostly negative Russian image in the public perception of Europeans,
today expression of negative tourism image of Russia, fears of tourist trips to the country. The article describes
the technology of implementation of the method of historical-graphical analysis as the part of the training. It also
describes the methods and forms of work with historical sources to identify perceptions of hospitality and tourism
images of Russia formed in the writings of foreign travelers of XIII–XIX centuries. Also the article contains some
fragments of descriptions of the peoples of Russia, their everyday life and customs contained in those writings,
shaped the imaginative perception of the country. The article states the pedagogical effectiveness of technology use
historical analysis to evaluate cause and effect the formation of negative or neutral tourist image of Russia among
foreign tourists, due to its descriptions in the historical sources. The conclusion is made about necessity of development
of marketing strategies for overcoming negative images and perceptions of Russia among potential users of
its tourism programs.
The use of tourism technologies in the process of Patriotic education
Authors: Молчанова Наталья , Molchanova Natalya 
Published: June 2016

The social apathy system came after the dissolution of the Soviet Union and the destruction of the ideological; the
recognized moral values, which had been universal for the Soviet people, disappeared. Representation of members
of a society about the absolute and unchanging moral principles were not relevant, in this regard, the society grew
into a community consisting of small groups, the main idea of which was the satisfaction of personal needs, often
unrelated to the needs of society in general. This article focuses on the possibilities of tourist activity in the Patriotic
education of citizens. Today the technology of tourism, in the sphere of pedagogical influence, is mainly used in the
practice of Patriotic education of the younger generation. However, the volume of tourism impact and its broader
educational opportunities cannot and should not be limited exclusively with Junior and youth direction. In modern
society there is a need of using the potential of tourist activities in the sphere of Patriotic education not only of youth
but also the adult population. Today there is a need for a focused educational process in patriotism, not beyond a
reasonable and humanistic perception of reality. Means of tourist activity of cultural-cognitive orientation such
as excursions and travel, priority aimed at acquainting with the history and culture of the Motherland, can be an
effective tool in the process of Patriotic education.
Role of the methodological component in the structure of the course training of guides and guide-interpreters (the preparation for the 2018 World Cup in Volgograd)
Authors: Ходякова Наталия , Khodyakova Nataliya , Ходяков Дмитрий , Khodyakov Dmitriy 
Published: June 2016

In connection with carrying out in 2018 of the activities of the world football Championship in several regions of
the Russian Federation there is a perceived need for additional training of a large number of guides, guides and
guides-interpreters. In the article based on modern scientific approaches and many years of practical experience,
the authors propose a new structure of the course content quality of training of specialists of excursion business. The
article discusses important differences in the training of the needed staff, on the one hand, in cities with experience
of international competitions and Championships – Olympic games and Universiades, and, on the other hand, in
cities where tourism business is seasonal e, which include the Volgograd. The article presents brief analysis of the
problems and difficulties encountered in the preparation and subsequent work of guides and guides-interpreters of
the Volgograd region. Special attention is paid to the insufficient competence of tour guides in the field of practice
of the excursion. In this context, the article provides an overview of tour guides requirements, contained in the normative legal acts on the basis of which there is competence of the guide – the guidelines of the tour. The authors
compare traditional (found in the literature) creative interpretations of the concept of «methodology of the tour».
As a significant component of the methodology for the conduct of excursions are the types of special methodical
knowledge of the guide and guide-interpreter, namely: psychological, pedagogical, vocational and applied, linguistic
knowledge and the practical skills: communicative, organizational and compensatory. The article specifies
requirements for teaching staff, conducting quality training courses guides and guide-interpreters, and procedural
characteristics of education.