bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complete Genome Sequence of a Lytic
Siphoviridae
Bacteriophage Infecting Several Serovars of Salmonella enterica
Authors: Paradiso Rubina , Lombardi Serena , Iodice Maria Grazia , Riccardi Marita Georgia , Orsini Massimiliano , Bolletti Censi Sergio , Galiero Giorgio , Borriello Giorgia 
Published: September 2016

ABSTRACT

The bacteriophage 100268_sal2 was isolated from water buffalo feces in southern Italy, exhibiting lytic activity against several subspecies of
Salmonella enterica
. This bacteriophage belongs to the
Siphoviridae
family and has a 125,114-bp double-stranded DNA (ds-DNA) genome containing 188 coding sequences (CDSs).
Complete Genome Sequence of Gordonia terrae 3612
Authors: Russell Daniel A. , Guerrero Bustamante Carlos A. , Garlena Rebecca A. , Hatfull Graham F. 
Published: September 2016

ABSTRACT

Here, we report the complete genome sequence of
Gordonia terrae
3612, also known by the strain designations ATCC 25594, NRRL B-16283, and NBRC 100016. The genome sequence reveals it to be free of prophage and clustered regularly interspaced short palindromic repeats (CRISPRs), and it is an effective host for the isolation and characterization of
Gordonia
bacteriophages.
Draft Genome Sequence of Bacillus litoralis C44, Isolated from Chinese Scholar Tree (
Sophora japonica
) Forest Soil
Authors: Lyu Weili , Wu Yunlong , Liu Ya , Lyu Zhitang 
Published: September 2016

ABSTRACT

Bacillus litoralis
C44 can hydrolyze rutin to produce isoquercetin by the enzyme α-
l
-rhamnosidase. We report here the genome sequence and annotation result of strain C44. The genomic information will serve as references to the physiology, genetics, and evolution of this species and further genetic engineering research in this species.
Draft Genome Sequence of Salmonella enterica subsp.
enterica
Serovar Orion Strain CRJJGF_00093 (Phylum
Gammaproteobacteria
)
Authors: Gupta Sushim K. , McMillan Elizabeth A. , Jackson Charlene R. , Desai Prerak T. , Porwollik Steffen , McClelland Michael , Hiott Lari M. , Humayoun Shaheen B. , Frye Jonathan G. 
Published: September 2016

ABSTRACT

Here, we report a 4.70-Mbp draft genome sequence of
Salmonella enterica
subsp.
enterica
serovar Orion strain CRJJGF_00093, isolated from a dog in 2005.
Structural equation model for estimating risk factors in type 2 diabetes mellitus in a Middle Eastern setting: evidence from the STEPS Qatar
Authors: Roman-Urrestarazu Andres , Ali Faleh Mohamed Hussain , Reka Husein , Renwick Matthew J , Roman Gabriela D , Mossialos Elias 
Published: September 2016

AimsUnderstanding type 2 diabetes mellitus is critical for designing effective diabetes prevention policies in Qatar and the Middle East.MethodsUsing the Qatar 2012 WHO STEPwise approach to surveillance survey, a subsample of 1224 Qatari participants aged 18–64 years was selected. Subjects had their fasting blood glucose levels tested, had not been diagnosed with or treated for diabetes, had a fasting time >12 hours and were not pregnant. We applied a hypothesized structural equation model (SEM) to assess sociodemographic, behavioral, anthropometric and metabolic variables affecting persons with type 2 diabetes mellitus.ResultsThere is a direct effect of triglyceride levels (0.336) and body mass index (BMI) (0.164) on diabetes status. We also found that physical activity levels negatively affect BMI (−0.148) and positively affect high-density lipoprotein (HDL) (0.106); sociodemographic background negatively affects diet (−0.522) and BMI (−0.352); HDL positively affects total cholesterol (0.230) and has a negative effect on BMI (−0.108), triglycerides (−0.128) and waist circumference (−0.104). Diet has a positive effect on triglycerides (0.281) while family history of diabetes negatively affects total cholesterol (−0.104). BMI has a positive effect on waist circumference (0.788) and mediates the effects of physical activity over diabetes status (−0.028). BMI also mediates the effects that sociodemographic factors (−0.058) and physical activity (−0.024) have on diabetes status. BMI and HDL (−0.002) together mediate the effect of physical activity on diabetes status and similarly HDL and tryglycerides (−0.005) also mediate the effect of physical activity on diabetes status. Finally diet and tryglycerides mediate the effects that sociodemographic factors have on diabetes status (−0.049).ConclusionsThis study's main finding is that triglyceride levels and BMI are the main variables directly affecting diabetes status in the Qatari population.
Guidelines of the International Federation of Red Cross and Red Crescent Societies: an overview and quality appraisal using AGREE II
Authors: Vande veegaete Axel , Borra Vere , De Buck Emmy , Vandekerckhove Philippe 
Published: September 2016

ObjectivesTo appraise the quality of guidelines developed by the International Federation of Red Cross and Red Crescent Societies (IFRC) between 2001 and 2015.Study designCross-sectional.Methods2 authors independently assessed the quality of IFRC guidelines using the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument. Average domain scores were calculated and overall quality scores and recommendation for use were determined.ResultsOut of 77 identified guidelines, 27 met the inclusion criteria and were assessed. The domains with the highest average scores across guidelines were ‘scope and purpose’, ‘clarity of presentation’ and ‘applicability’. The lowest scoring domains were ‘rigour of development’ and ‘editorial independence’. No guideline can be ‘recommended for immediate use’, 23 guidelines are ‘recommended with modifications’ and 4 guidelines are ‘not recommended’.ConclusionsThe IFRC produces guidelines that should be adhered to by millions of staff and volunteers in 190 countries. These guidelines should therefore be of high quality. Up until now, the IFRC had no uniform guideline development process. The results of the AGREE II appraisal indicate that the quality of the guidelines needs to be improved.
Evidence-based interventions to reduce adverse events in hospitals: a systematic review of systematic reviews
Authors: Zegers Marieke , Hesselink Gijs , Geense Wytske , Vincent Charles , Wollersheim Hub 
Published: September 2016

ObjectiveTo provide an overview of effective interventions aimed at reducing rates of adverse events in hospitals.DesignSystematic review of systematic reviews.Data sourcesPubMed, CINAHL, PsycINFO, the Cochrane Library and EMBASE were searched for systematic reviews published until October 2015.Study selectionEnglish-language systematic reviews of interventions aimed at reducing adverse events in hospitals, including studies with an experimental design and reporting adverse event rates, were included. Two reviewers independently assessed each study's quality and extracted data on the study population, study design, intervention characteristics and adverse patient outcomes.ResultsSixty systematic reviews with moderate to high quality were included. Statistically significant pooled effect sizes were found for 14 types of interventions, including: (1) multicomponent interventions to prevent delirium; (2) rapid response teams to reduce cardiopulmonary arrest and mortality rates; (3) pharmacist interventions to reduce adverse drug events; (4) exercises and multicomponent interventions to prevent falls; and (5) care bundle interventions, checklists and reminders to reduce infections. Most (82%) of the significant effect sizes were based on 5 or fewer primary studies with an experimental study design.ConclusionsThe evidence for patient-safety interventions implemented in hospitals worldwide is weak. The findings address the need to invest in high-quality research standards in order to identify interventions that have a real impact on patient safety. Interventions to prevent delirium, cardiopulmonary arrest and mortality, adverse drug events, infections and falls are most effective and should therefore be prioritised by clinicians.
Elevated levels of autophagy-related marker ULK1 and mitochondrion-associated autophagy inhibitor LRPPRC are associated with biochemical progression and overall survival after androgen deprivation therapy in patients with metastatic prostate cancer
Authors: Zhang Hong-Yi , Ma Ya-Dong , Zhang Ye , Cui Jie , Wang Zi-Ming 
Published: September 2016

AimTo evaluate the expression levels and prognostic significance of autophagy-related markers, UNC-51-like kinase1 (ULK1), Beclin1, microtubule-associated protein light chain 3 (LC3), autophagy-related gene 5 (ATG5) and mitochondrion-associated autophagy inhibitor, LRPPRC, in patients with metastatic prostate cancer (PCa) after androgen deprivation therapy (ADT).MethodsExpressions of ULK1, Beclin1, LC3, ATG5 and LRPPRC were assessed by immunohistochemical examination in 198 patients with metastatic PCa who were receiving ADT (goserelin and bicalutamide).ResultsHigh expression levels of LRPPRC and ULK1were significantly associated with Gleason score, serum prostate-specific antigen (PSA) levels, PSA levels after ADT and number of metastatic sites. High expression of ULK1 in patients with concomitant high expression of LRPPRC was significantly associated with multiple metastases, shorter biochemical progression (BCP)-free survival and shorter overall survival (OS). ULK1 expression, LRPPRC expression, Gleason score, PSA levels after ADT and number of metastatic sites were independently associated with shorter BCP-free survival and OS on multivariate analysis. Furthermore, two-year BCP rate of patients with ≥3 risk factors was found to be significantly higher as compared with that of patients with ≤1 and 2 risk factors. Three-year OS rate in patients with ≥3 risk factors was significantly lower than that of those with ≤1 and 2 risk factors.ConclusionsHigh expression of ULK1 concomitant with high expression of LRPPRC may serve as useful markers for shorter BCP-free survival and OS in patients with metastatic PCa after ADT.
Lamb waves propagation in a novel metal-matrix phononic crystals plate
Authors: Li Suobin , Chen Tianning , Wang Xiaopeng , Xi Yanhui 
Published: September 2016

In this paper, the propagation properties of Lamb waves in a novel phononic crystals (PCs) plate composed of a square array of double-sided composite taper stubs, which are deposited on a 2D locally resonant PC plate that composes of an array of rubber fillers embedded in the steel plate is studied. It is shown that the spring–mass system of the resonator will be decoupled by introducing the rubber filler, and then the out-of-plane band gap (BG) and the in-plane BG can be adjusted into the same lowest frequency range, respectively (the out-of-plane BG is adjusted by the rubber filler and the in-plane BG is adjusted by the taper stub). As a result, the frequency range of the generated complete BG is between 59–93 Hz due to the overlap between the in-plane and out-of-plane BG. Compared with the classic double-sided stubbed PC plate, the relative bandwidth of the BG is enlargement by a factor of 5.5 and the location of the BG is reduced by a factor of 5.5 in the proposed structure. It provides an effective way for metal-matrix PCs to obtain complete BGs in low-frequency range (below 100 Hz), which has potential for the reduction of the vibration at low frequency in practical case.
МОДЕЛЮВАННЯ ЗАВИТКИ ВНУТРІШНЬОГО ВУХА ЛЮДИНИ
Authors: Naida S. A. , Zubchenko О. A. 
Published: September 2016

<p>There was conducted the simulations of a cochlea of an interior ear of the human by means of a long line. The following regularities of operation of a cochlea were determined: without the count of flexibilities Reissner's and basilar membranes swing pressure on walls of a cochlear course does not exceed 3,6 % from pressure in the field of an oval window; allocation of a differential of sound pressure fluctuates in a time with frequency; taking into account the slenderness of a membrane and dependence of a standing of resonances from <em>f </em>are spotted by non-uniformity of a basilar membrane; the differential travelling wave exists only near to a resonance on each frequency where the amplitude buildup of oscillations to a maximum happens for many continuances of resonance frequency.</p><p>Small relative meaning of range of pressure of travelling wave could become the parent of that Peterson's and Bogert's work has not had the further evolution.</p>
Local Matrix Metalloproteinase 9 Level Determines Early Clinical Presentation of ST-Segment–Elevation Myocardial Infarction
Authors: Nishiguchi Tsuyoshi , Tanaka Atsushi , Taruya Akira , Emori Hiroki , Ozaki Yuichi , Orii Makoto , Shiono Yasutsugu , Shimamura Kunihiro , Kameyama Takeyoshi , Yamano Takashi , Yamaguchi Tomoyuki , Matsuo Yoshiki , Ino Yasushi , Kubo Takashi , Hozumi Takeshi , Hayashi Yasushi , Akasaka Takashi 
Published: September 2016

Objective—
Early clinical presentation of ST-segment–elevation myocardial infarction (STEMI) and non–ST-segment–elevation myocardial infarction affects patient management. Although local inflammatory activities are involved in the onset of MI, little is known about their impact on early clinical presentation. This study aimed to investigate whether local inflammatory activities affect early clinical presentation.

Approach and Results—

This study comprised 94 and 17 patients with MI (STEMI, 69; non-STEMI, 25) and stable angina pectoris, respectively. We simultaneously investigated the culprit lesion morphologies using optical coherence tomography and inflammatory activities assessed by shedding matrix metalloproteinase 9 (MMP-9) and myeloperoxidase into the coronary circulation before and after stenting. Prevalence of plaque rupture, thin-cap fibroatheroma, and lipid arc or macrophage count was higher in patients with STEMI and non-STEMI than in those with stable angina pectoris. Red thrombus was frequently observed in STEMI compared with others. Local MMP-9 levels were significantly higher than systemic levels (systemic, 42.0 [27.9–73.2] ng/mL versus prestent local, 69.1 [32.2–152.3] ng/mL versus poststent local, 68.0 [35.6–133.3] ng/mL;
P
<0.01). Poststent local MMP-9 level was significantly elevated in patients with STEMI (STEMI, 109.9 [54.5–197.8] ng/mL versus non-STEMI: 52.9 [33.0–79.5] ng/mL; stable angina pectoris, 28.3 [14.2–40.0] ng/mL;
P
<0.01), whereas no difference was observed in the myeloperoxidase level. Poststent local MMP-9 and the presence of red thrombus are the independent determinants for STEMI in multivariate analysis.

Conclusions—
Local MMP-9 level could determine the early clinical presentation in patients with MI. Local inflammatory activity for atherosclerosis needs increased attention.
Location of In‐Hospital Cardiac Arrest in the United States—Variability in Event Rate and Outcomes
Authors: Perman Sarah M. , Stanton Emily , Soar Jasmeet , Berg Robert A. , Donnino Michael W. , Mikkelsen Mark E. , Edelson Dana P. , Churpek Matthew M. , Yang Lin , Merchant Raina M. , Nichol Graham , Nadkarni Vinay M. , Peberdy Mary Ann , Chan Paul S. , Mader Tim , Kern Karl B. , Warren Sam , Allen Emilie , Eigel Brian , Hunt Elizabeth A. , Ornato Joseph P. , Braithwaite Scott , Geocadin Romergryko G. , Mancini Mary E. , Potts Jerry , Truitt Tanya Lane 
Published: September 2016

Background

In‐hospital cardiac arrest (
IHCA
) is a major public health problem with significant mortality. A better understanding of where
IHCA
occurs in hospitals (intensive care unit [
ICU
] versus monitored ward [telemetry] versus unmonitored ward) could inform strategies for reducing preventable deaths.

Methods and Results

This is a retrospective study of adult
IHCA
events in the Get with the Guidelines—Resuscitation database from January 2003 to September 2010. Unadjusted analyses were used to characterize patient, arrest, and hospital‐level characteristics by hospital location of arrest (
ICU
versus inpatient ward).
IHCA
event rates and outcomes were plotted over time by arrest location. Among 85 201
IHCA
events at 445 hospitals, 59% (50 514) occurred in the
ICU
compared to 41% (34 687) on the inpatient wards. Compared to ward patients,
ICU
patients were younger (64±16 years versus 69±14;
P
<0.001) and more likely to have a presenting rhythm of ventricular tachycardia/ventricular fibrillation (21% versus 17%;
P
<0.001). In the
ICU
, mean event rate/1000 bed‐days was 0.337 (±0.215) compared with 0.109 (±0.079) for telemetry wards and 0.134 (±0.098) for unmonitored wards. Of patients with an arrest in the
ICU
, the adjusted mean survival to discharge was 0.140 (0.037) compared with the unmonitored wards 0.106 (0.037) and telemetry wards 0.193 (0.074). More
IHCA
events occurred in the
ICU
compared to the inpatient wards and there was a slight increase in events/1000 patient bed‐days in both locations.

Conclusions

Survival rates vary based on location of
IHCA
. Optimizing patient assignment to unmonitored wards versus telemetry wards may contribute to improved survival after
IHCA
.
Simulation of Airborne Transport and Dispersion for Urban Waterside Releases
Authors: Meir Talmor , Pullen Julie , Blumberg Alan F. , Holt Teddy R. , Bieringer Paul E. , Bieberbach George 
Published: September 2016

AbstractResults are presented from a tracer-release modeling study designed to examine atmospheric transport and dispersion (“T&D”) behavior surrounding the complex coastal–urban region of New York City, New York, where air–sea interaction and urban influences are prominent. The puff-based Hazard Prediction Assessment Capability (HPAC, version 5) model is run for idealized conditions, and it is also linked with the urbanized COAMPS (1 km) meteorological model and the NAM (12 km) meteorological model. Results are compared with “control” plumes utilizing surface meteorological input from 22 weather stations. In all configurations, nighttime conditions result in plume predictions that are more sensitive to small changes in wind direction. Plume overlap is reduced by up to 70% when plumes are transported during the night. An analysis of vertical plume cross sections and the nature of the underlying transport and the dispersion equations both suggest that heat flux gradients and boundary layer height gradients determine vertical transport of pollutants across land–sea boundaries in the T&D model. As a consequence, in both idealized and realistic meteorological configurations, waterfront releases generate greater plume discrepancies relative to plumes transported over land/urban surfaces. For transport over water (northwest winds), the higher-fidelity meteorological model (COAMPS) generated plumes with overlap reduced by about one-half when compared with that of the coarser-resolution NAM model (13% vs 24% during the daytime and 11% vs 18% during the nighttime). This study highlights the need for more sophisticated treatment of land–sea transition zones in T&D calculations covering waterside releases.
Regional Hydrological Cycle over the Red Sea in ERA-Interim
Authors: Zolina Olga , Dufour Ambroise , Gulev Sergey K. , Stenchikov Georgiy 
Published: September 2016

Abstract
The major sources of atmospheric moisture over the Red Sea are analyzed using ERA-Interim for the 1979–2013 period. The vertical structure of moisture transports across the coastlines has been computed separately for the western and eastern coasts of the Red Sea. The vertical structure of the moisture transport from the Red Sea to the continents is dominated by a breeze-like circulation in the near-surface layer and the Arabian high above 850 hPa. The lower-layer, breeze-like circulation is acting to export the moisture to the northwest of Africa and to the Arabian Peninsula and contributes about 80% of the moisture exports from the Red Sea, dominating over the transport in the upper layer, where the moisture is advected to the Arabian Peninsula in the northern part of the sea and to the African continent in the southern part. Integrated moisture divergence over the Red Sea decreased from the early 1980s to 1997 and then increased until the 2010s. Associated changes in the moisture export were provided primarily by the increasing intensity of the breeze-associated transports. The transports above the boundary layer, while being strong across the western and the eastern coasts, have a smaller effect on the net moisture export. The interannual variability of the moisture export in the near-surface layer was found to be closely correlated with the variability in sea surface temperature, especially in summer. Implications of the observed changes in the moisture advection for the hydrological cycle of the Middle East are discussed.
The Color of Alternatives? Rethinking Nonviolent Actions in the Twenty-First Century
Authors: Satha-Anand Chaiwat 
Published: September 2016

AbstractThis article argues that nonviolence in the twenty-first century would increasingly be moving towards the color gray by addressing three related questions. First, given the way in which the media reported the news, how can the twentieth century be remembered especially in relation to what has taken place at the dawn of the twenty-first century? Second, how should “unusual” nonviolent protest actions – throwing shit, blood, and shoes at people – be construed from the perspective of nonviolent alternatives? Third, as more parties become interested and consequently nonviolent actions become widespread, are they becoming less of an alternative and more of a normal course of action? As a result of the mainstreaming nonviolence trend, has anything been taken away from it? Confronting these questions as a way to critically examine the prospects for nonviolent actions at present, the paper concludes with a philosophical argument in favor of gray as the color of nonviolent alternatives in the twenty-first century.
Spaces in-Between: Exile, Emigration, and the Performance of Memory in Zahra's Mother Tongue
Authors: Petty Sheila 
Published: September 2016

AbstractIn her 2011 documentary, La Langue de Zahra/Zahra's Mother Tongue, Algerian/French filmmaker Fatima Sissani “gives voice” to her Kabyle mother, Zahra, who lived in France as an immigrant woman for years after Algerian independence without speaking French. Often considered uneducated and ignorant, these women act as archives of oral tradition, history, and poetry in a language their children often do not speak. In this paper, I will look at how this performative documentary film creates “spaces in-between” cultures through its uses of performance, orality, and cinematic space. A number of recent Maghrebi and sub-Saharan African documentaries have emerged that can be described as performative documentaries in which historical evocation and emotive connection to the subject matter is as important to the filmmaker as factual referencing. The filmmaker plays a self-reflexive role in the text, which often shapes the content.It is important to note that the film is not about being forced to choose between two geographical locations, and it does not seek to hybridize two cultures, but rather is concerned with other sorts of questions such as the nature of Berber culture and language, how it impacts not only the representation of Algeria's post-Independence history (the troubled context of the 1990s, the history of Algerian migration to France), but also the practice and aesthetics of this contemporary documentary filmmaker. The film suggests possible new ways of looking at questions of minority language (Kabyle), culture, and identity that could potentially greatly contribute to the understanding of contemporary independent documentary film practices, discourses, and aesthetics.
Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties
Authors: Chu Haiyan , McKenna Mary M. , Krump Nathan A. , Zheng Suilan , Mendelsohn Laurel , Thein Swee Lay , Garrett Lisa J. , Bodine David M. , Low Philip S. 
Published: September 2016

Key PointsThe reversible association of deoxyHb with band 3 acts as an O2-triggered molecular switch to regulate erythrocyte properties. Transgenic mice lacking the deoxyHb site on band 3 fail to respond to changes in O2 with changes in erythrocyte properties.