bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategi Pengembangan Agribisnis Jambu Gondang Manis (Syzygium malances) di Kabupaten Jombang
Authors: Suhadi Agus 
Published: September 2024

Kabupaten Jombang adalah salah satu penghasil produk unggulan buah yang telah dilepas oleh Menteri Pertanian RI No: 308/Kpts/SR.120/4/2006 tentang pelepasan Jambu bol Gondang Manis sebagai Vatrietas Unggul adalah Jambu Gondang manis, memiliki potensial tinggi dengan warna buah menarik (Unggu kehitaman jika buah telah tua, dengan rasa manis segar, dengan warna daing putih seperti kapas dengan aroma buah yang harum. Terletak di Desa Gondang Manis Kecamatan Bandar Kedung Mulyo Kabupaten Jombang. Tujuan dari penelitian ini adalah untuk mengidentifikasi faktor faktor yang berpengaruh dan strategi yang tepat dalam pengembangan agribisnis jambu Gondang manis,untuk Lokasi penelitian dilakukan di desa Gondang Manis Kecamatan Bandar Kedung Mulyo, Kabupaten Jombang. Penelitian ini dilakukan selama (tiga) bulan yakni antara bulan April â€“ Juni 2019. Data yang digunakan dalam penelitian ini adalah data primer dan data sekunder. Data primer adalah data yang diambil langsung dari lokasi penelitian di desa Gondang Manis, melalui pengamatan langsung di lokasi, wawancara dengan pihak pemerintah, toko masyarakat, dan pengisian kuesioner. Responden yang dipilih 15 orang untuk mengisi kuesioner penelitian sebagai berikut : Pemerintah (2 orang), yaitu Kepala desadan perangkat,Pegawai Dinas Pertanian Jombang (1 orang) Toko Masyarakat (2 orang), Pelaku utama (8 orang), dan PODARWIS (2 orang). Data sekunder adalah data yang diperoleh melalui instansi terkait dengan penelitian ini, baik tabulasi maupun deskriptif. Metode analisis yang digunakan adalah analisis SWOT dan QSPM. Berdasarkan hasil penelitian dan pembahasan, maka dapat disimpulkan bahwa alternatif strategi pengembangan Agribisnis jambu gondang manis yang tepat adalah Strategi SO yaitu Strategi pengembangan agribisnis Jambu Gondang manis dengan memadukan antara Agroekologi di Desa Gondanf manis yang sudah sesuai dengan SDM yang berkualitas, adopsi teknologi untuk menciptakan buah yang unggul, dapat berbuah di luar musim yang lain serta menjga kekhasan jambu gondang manis .nilai daya tarik tertinggi terdapat pada strategi 1 (SO) dengan jumlah total daya tarik (TAS) sebesar 6,85. dengan melakukan action antara pemerintah Daerah, Pelaku utama, Tokoh masyarakatBumdes saling terpadu untuk menciptakan buah jambu gondang manis yang unggul baik secara kualitas maupun kuantitas dan melindungi asset jambu Gondang manis yang sudah dilepas oleh Menteri Pertanian dengan meningkatkan potensi dan tindakan pelestarian jambu Gondang manis yang ada sebagai ciri khas yang dimiliki oleh daerah Desa Gondang Manis Kecamatan Bandar kedung Mulyo Jombang.
PENINGKATAN HASIL BELAJAR MATEMATIKA PERTIDAKSAMAAN IRASIONAL DENGAN STRATEGI PEMBELAJARAN DISCOVERY
Authors: - Waritsatul chasanah , Nasrulloh M Farid , Darmawan Moh faridl 
Published: September 2024

Penelitian ini dilatar belakangi hasil pengamatan dan pengalaman peneliti, bahwa motivasi belajar peserta didik di MA Bahrul â€˜Ulum Tambakberas Jombang rendah. Akibatnya mempengaruhi hasil belajar matematika yang rendah. Tujuan penelitian ini adalah 1) Penerapan strategi pembelajaran discovery terhadap motivasi belajar peserta didik kelas X MIA 1 Tambakberas Jombang pada materi pertidaksamaan irasional, 2) Hasil belajar peserta didik kelas X MIA 1 Tambakberas Jombang setelah penerapan strategi pembelajaran discovery pada materi pertidaksamaan irasional. Penelitian ini menggunakan metode penelitian kualitatif dengan subyek penelitian 16 peserta didik kelas X MIA 1 Tambakberas Jombang. Penelitian dilaksanakan selama 4 pertemuan dan menggunakan instrumen berupa RPP, lembar observasi peserta didik, lembar kerja peserta didik, dan soal tes. Berdasarkan data dari analisis observasi peserta didik, dapat diketahui motivasi peserta didik tinggi, sehingga peserta didik tekun dan semangat selama kegiatan pembelajaran dan mempengaruhi hasil belajar matematika yang lebih baik dari sebelumnya.
Kata Kunci: Strategi pembelajaran discovery, Motivasi belajar, dan Hasil belajar.
Penelitian ini dilatar belakangi hasil pengamatan dan pengalaman peneliti, bahwa motivasi belajar peserta didik di MA Bahrul â€˜Ulum Tambakberas Jombang rendah. Akibatnya mempengaruhi hasil belajar matematika yang rendah. Tujuan penelitian ini adalah 1) Penerapan strategi pembelajaran discovery terhadap motivasi belajar peserta didik kelas X MIA 1 Tambakberas Jombang pada materi pertidaksamaan irasional, 2) Hasil belajar peserta didik kelas X MIA 1 Tambakberas Jombang setelah penerapan strategi pembelajaran discovery pada materi pertidaksamaan irasional. Penelitian ini menggunakan metode penelitian kualitatif dengan subyek penelitian 16 peserta didik kelas X MIA 1 Tambakberas Jombang. Penelitian dilaksanakan selama 4 pertemuan dan menggunakan instrumen berupa RPP, lembar observasi peserta didik, lembar kerja peserta didik, dan soal tes. Berdasarkan data dari analisis observasi peserta didik, dapat diketahui motivasi peserta didik tinggi, sehingga peserta didik tekun dan semangat selama kegiatan pembelajaran dan mempengaruhi hasil belajar matematika yang lebih baik dari sebelumnya.
Kata Kunci: Strategi pembelajaran discovery, Motivasi belajar, dan Hasil belajar.
STRATEGI MNEMONIC DALAM PEMBELAJARAN MATEMATIKA
Authors: Verdianingsih Eliza 
Published: September 2024

ABSTRACT
Memory play an important role in education since it is one of the aspects that determine studentsâ€™ achievement. One that indicates sucessful learning is when students can remember what the teachers has taught. Mathematics is a lesson that is related to other studies. Each study consists of definition, formula, theorem and algorithm. Students are ought to remember and understand them to solve mathematical problems. Therefore, strategy of teaching which can help students to remember and understand the lesson, specifically for mathematics is needed. Mnemonic is one of strategies that can answer that problems. The methodology that is used in this article is literature study to gain deeper understanding about mnemonic strategy, specifically mnemonic srategy in mathematics. This article explains definition, techniques and benefit of mnemonic strategy. Furthermore, it will also explain mnemonic strategy in mathematics education.
KEYWORDS: memory, mnemonic strategy, mathematic education

ABSTRAK
Memori atau ingatan memiliki peranan penting dalam suatu proses pembelajaran, karena memori merupakan salah satu hal yang dapat menentukan prestasi belajar peserta didik. Semua proses pembelajaran tidak akan ada hasilnya jika peserta didik tidak mampu mengingat materi pelajaran yang telah diajarkan. Matematika merupakan salah satu materi pelajaran yang terdiri dari berbagai bidang kajian. Setiap bidang kajian matematika berisi berbagai macam definisi, rumus, teorema dan algoritma. Peserta didik harus mengingat dan memahami hal tersebut untuk menyelesaikan masalah matematika. Oleh karena itu diperlukan strategi pembelajaran yang dapat membantu peserta didik dalam mengingat dan memahami materi pelajaran, khususnya matematika. Strategi pembelajaran tersebut adalah strategi mnemonic. Metodologi dalam artikel ini adalah kajian literatur untuk menggali pengetahuan tentang strategi mnemonic, khususnya strategi mnemonic dalam pembelajaran matematika. Artikel ini membahas tentang pengertian, teknik-teknik, dan manfaat dari strategi mnemonic. Selain itu juga dibahas tentang strategi mnemonic dalam pembelajaran matematika.
KATA KUNCI: memori, strategi mnemonic, pembelajaran matematika
PENDEKATAN HOLISTIK DALAM MENINGKATKAN PEMBELAJARAN BAHASA ARAB
Authors: Afroni Mochamad 
Published: September 2024

Abstraks
Dalam pembelajaran bahasa Arab, terdapat empat maharah yang harus dikuasai oleh para peserta didik, yaitu maharah istimaâ€™, maharah kalam, maharah kitabah dan maharah qiroâ€™ah. Keempat maharah tersebut tidak dapat dipisahkan satu dengan yang lainnya. Dalam tulisan ini penulis membahas tentang pembelajaran bahasa dengan menggunakan pendekatan holistik. Dengan menggunakan pendekatan holistik keempat maharah tersebut dapat diajarkan secara menyeluruh. Tujuan penelitian ini yaitu untuk mengetahui potensi peserta didik dalam pembelajaran bahasa Arab dengan menggunakan pendekatan holistik. Metode yang digunakan penulis untuk mencapai tujuan tersebut yaitu dengan menggunakan metode kualitatif. Pengumpulan data dilakukan dengan metode observasi non partisipasi (nonparticipatory observation). Hasil yang diperoleh dari penelitian ini adalah yaitu meningkatnya spiritualitas peserta didik, meningkatkan pemahaman pelajaran bahasa arab, pembelajaran yang aplikatif dan efektif, dan mewujudkan pribadi berkarakter. Selain itu, peserta didik dapat belajar bahasa arab secara utuh, lingkungan belajar yang berintergritas, mewujudkan pribadi berintegritas antara individu dan sosial, fokus dalam belajar, mengembangkan peserta didik sesuai potensi.
Evaluating Lung Changes in Long COVID: Ultra-Low‐Dose vs. Standard‐Dose CT Chest
Authors: Devkota Shritik , Garg Mandeep , Debi Uma , Dhooria Sahajal , Dua Ashish , Prabhakar Nidhi , Soni Saumya , Maralakunte Muniraju , Gulati Ajay , Singh Tarvinder , Sandhu Manavjit Singh 
Published: September 2024

BackgroundFrequent chest CTs within a short period during follow-up of long COVID patients may increase the risk of radiation-related health effects in the exposed individuals. We aimed to assess the image quality and diagnostic accuracy of ultra-low-dose CT (ULDCT) chest compared to standard-dose CT (SDCT) in detecting lung abnormalities associated with long COVID.MethodsIn this prospective study, 100 long COVID patients with respiratory dysfunction underwent SDCT and ULDCT chest that were compared in terms of objective (signal-to-noise ratio, SNR) and subjective image quality (image graininess, sharpness, artifacts, and diagnostic accuracy along with the European guidelines on image quality criteria for CT chest), detection of imaging patterns of long COVID, CT severity score, and effective radiation dose. Additionally, the diagnostic performance of ULDCT was compared among obese (BMI≥30 kg/m2) and non-obese (BMI&lt;30 kg/m2) subjects.ResultsThe mean age of study participants was 53 ± 12.9 years, and 68% were male. The mean SNR was 31.4 ± 5.5 and 11.3 ± 4.6 for SDCT and ULDCT respectively (p&lt; 0.0001). Common findings seen on SDCT included ground-glass opacities (GGOs, 77%), septal thickening/reticulations (67%), atelectatic/parenchymal bands (63%) and nodules (26%). ULDCT provided sharp images, with no/minimal graininess, and high diagnostic confidence in 81%, 82% and 80% of the cases respectively. The sensitivity of ULDCT for various patterns of long COVID was 72.7% (GGOs), 71.6% (interlobular septal thickening/reticulations), 100% (consolidation), 81% (atelectatic/parenchymal bands) and 76.9% (nodules). ULDCT scans in non-obese subjects exhibited a significantly higher sensitivity (88% vs. 60.3%, p &lt; 0.0001) and diagnostic accuracy (97.7% vs. 84.9%, p &lt; 0.0001) compared to obese subjects. ULDCT showed very strong correlation with SDCT in terms of CT severity score (r = 0.996, p &lt; 0.0001). The mean effective radiation dose with ULDCT was 0.25 ± 0.02 mSv with net radiation dose reduction of 94.8% ± 1.7% (p &lt; 0.0001) when compared to SDCT (5.5 ± 1.96 mSv).ConclusionULDCT scans achieved comparable diagnostic accuracy to SDCT for detecting long COVID lung abnormalities in non-obese patients, while significantly reducing radiation exposure.
A new strategy in bioreactor scale-up and process transfer using a dynamic initial vvm according to different aeration pore size
Authors: Ding Huaping , Cheng Huanghe , Wu Jiaxian , Zhang Fan , Cao Can , Mualif Siti Aisyah , Xie Zhenggang 
Published: September 2024

Monoclonal antibody drugs have grown into a drug category with a market size of over $100 billion since the first product was launched on the market, which naturally creates a large demand for production. At the same time, the $100 billion market is distributed among more than 200 listed drugs, which indicates that the production demand for monoclonal antibody drugs is diverse. To meet this demand, major suppliers offer single-use bioreactors of all sizes. These single-use bioreactors with different specifications, especially the inconsistency of aeration pore sizes, pose great challenges for technology transfer and scale-up production, and the conventional scale-up strategies of constant Power input/volume ratio (P/V) and constant vessel volume per minute (vvm) can no longer meet the needs. This study simplified the selection of technical parameters in bioreactors based on the differences in aeration pore size. Innovatively combined the aeration pore sizes with initial aeration vvm, and comprehensively investigated the relationship between P/V, vvm and aeration pore size by designing experiments (DoE) using the orthogonal test method. The results showed a quantitative relationship between the aeration pore size and the initial aeration vvm in the P/V range of 20 ± 5 W/m3. The appropriate initial aeration was between 0.01 and 0.005 m3/min for aeration pore size ranging from 1 to 0.3 mm, which was the optimal incubation condition in the bioreactors. The choice of initial ventilation was most related to the final expression. Follow-up studies validated these findings in a 15 L glass bioreactor and a 500 L single-use bioreactor, and the results were consistent with expectations.
Cardiovascular disease in thymic cancer patients
Authors: Khemka Abhishek , Clasen Suparna C. , Loehrer Patrick J. , Roberts Anna R. , Golzarri-Arroyo Lilian , Badve Sunil S. , Raman Subha V. , Hui Siu L. , Schleyer Titus K. L. 
Published: September 2024

IntroductionCancer patients may have increased risk for adverse cardiac events, but our understanding of cardiovascular risk in thymic cancer patients is not clear. We sought to characterize baseline cardiometabolic risk factors before thymic cancer diagnosis and the potential association between cancer treatment and subsequent cardiac events.MethodsThis was a retrospective cohort study evaluating patients with thymic cancer from 2003 to 2020 compared to age- and sex-matched controls without cancer. Baseline cardiovascular risk factors, cancer characteristics, and incidence of cardiac events were collected from the health information exchange. Multivariable regression was used to examine the impact of cardiovascular risk factors and cancer therapies.ResultsWe compared 296 patients with pathology-confirmed thymic cancer to 2,960 noncancer controls. Prior to cancer diagnosis, thymic cancer patients (TCPs) had lower prevalence of hypertension, dyslipidemia, and diabetes mellitus and similar rates of obesity, tobacco use, and pre-existing cardiovascular disease (CVD) compared to controls. After diagnosis, high-risk TCPs (&gt;2 cardiovascular risk factors or pre-existing CVD) had higher risk for cardiac events (HR 3.73, 95% CI 2.88–4.83, p &lt; 0.001). In the first 3 years after diagnosis, TCPs had higher incidence of cardiac events (HR 1.38, 95% CI 1.01–1.87, p = 0.042). High-risk TCPs who received radiotherapy or chemotherapy had higher risk of cardiac events (HR 4.99, 95% CI 2.30–10.81, p &lt; 0.001; HR 6.24, 95% CI 2.84–13.72, p &lt; 0.001).Discussion/conclusionCompared to noncancer controls, TCPs experienced more cardiac events when adjusted for risk factors. Patients with multiple cardiovascular risk factors receiving radiotherapy or chemotherapy had higher incidence of cardiac events.
Ten-year clinical outcomes of everolimus- and biolimus-eluting coronary stents vs. everolimus-eluting bioresorbable vascular scaffolds—insights from the EVERBIO-2 trial
Authors: Bengueddache Samir , Cook Malica , Lehmann Sonja , Arroyo Diego , Togni Mario , Puricel Serban , Cook Stephane 
Published: September 2024

BackgroundBioresorbable vascular scaffolds (BVSs) have been developed as a potential solution to mitigate late complications associated with drug-eluting metallic stents (DESs) in percutaneous coronary intervention for coronary artery disease. While numerous studies have compared BVSs to DESs, none have assessed clinical outcomes beyond 5 years.ObjectivesThis study aimed to compare the 10-year clinical outcomes of patients treated with BVSs vs. DESs.MethodsThe EverBio-2 trial (Comparison of Everolimus- and Biolimus-Eluting Coronary Stents with Everolimus-Eluting Bioresorbable Vascular Scaffold) is a single-center, assessor-blinded, randomized controlled trial that enrolled 240 patients allocated in a 1:1:1 ratio to receive BVSs, everolimus-eluting stents, or biolimus-eluting stents (BESs). Clinical follow-up was scheduled for 10 years.ResultsClinical follow-up was completed in 222 patients (93%) at the 10-year mark. The rate of device-oriented composite events (DOCE) was 28% in the DES group and 29% in the BVS group (p = 0.72) at 10 years. Similarly, the rate of patient-oriented composite events (POCE) was 55% in the DES group and 49% in the BVS group (p = 0.43) at 10 years. Notably, the rate of myocardial infarction (MI) within the target vessel was 5% in the BVS group and 0% in the BES group (p = 0.04), while the rate of any MI was 10% in the BVS group and 2% in the BES group (p = 0.04). In addition, the rate of Academic Research Consortium (ARC) possible stent thrombosis was 3% in the BVS group and 0% in the DES group (p = 0.04).ConclusionsOver 10 years, the rates of clinical DOCE and POCE were similar between the BVS and DES groups but individual outcomes of stent thrombosis were higher (3%) in the BVS group compared to the DES group.
Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT01711931).
A stacked machine learning-based classification model for endometriosis and adenomyosis: a retrospective cohort study utilizing peripheral blood and coagulation markers
Authors: Wang Weiying , Zeng Weiwei , Yang Sen 
Published: September 2024

IntroductionEndometriosis (EMs) and adenomyosis (AD) are common gynecological diseases that impact women's health, and they share symptoms such as dysmenorrhea, chronic pain, and infertility, which adversely affect women's quality of life. Current diagnostic approaches for EMs and AD involve invasive surgical procedures, and thus, methods of noninvasive differentiation between EMs and AD are needed. This retrospective cohort study introduces a novel, noninvasive classification methodology employing a stacked ensemble machine learning (ML) model that utilizes peripheral blood and coagulation markers to distinguish between EMs and AD.MethodsThe study included a total of 558 patients (329 with EMs and 229 with AD), in whom key hematological and coagulation markers were analyzed to identify distinctive profiles. Feature selection was conducted through ML (logistic regression, support vector machine, and K-nearest neighbors) to determine significant hematological markers.ResultsRed cell distribution width, mean corpuscular hemoglobin concentration, activated partial thromboplastin time, international normalized ratio, and antithrombin III were proved to be the key distinguishing indexes for disease differentiation. Among all the ML classification models developed, the stacked ensemble model demonstrated superior performance (area under the curve = 0.803, 95% credibility interval = 0.701–0.904). Our findings demonstrate the effectiveness of the stacked ensemble ML model for classifying EMs and AD.DiscussionIntegrating biomarkers into this multi-algorithm framework offers a novel approach to noninvasive diagnosis. These results advocate for the application of stacked ensemble ML utilizing cost-effective and readily available peripheral blood and coagulation indicators for the early, rapid, and noninvasive differential diagnosis of EMs and AD, offering a potentially transformative approach for clinical decision-making and personalized treatment strategies.
Unveiling the influence of persuasion strategies on cognitive engagement: an ERPs study on attentional search
Authors: Xiu Lichao , Chen Xuejiao , Mao Lulu , Zhang Enyu , Yu Guoming 
Published: September 2024

The objective of this study was to explore the impact of different persuasive strategies, as delineated in the Elaboration Likelihood Model (ELM), on attentional processes using event-related potentials (ERPs).IntroductionThis study aimed to investigate how central versus peripheral persuasion methods, delivered through rational and emotional persuasion strategies, influence cognitive engagement and information processing during visual search tasks.MethodsParticipants were allocated into four groups based on the media type (video vs. text) and the persuasion route (central vs. peripheral). The early and late stages of attentional processing were examined through the N1, P2, and P3 ERP components.ResultsThe results demonstrated a pronounced N1 amplitude in response to text-based peripheral persuasion, indicating enhanced early attentional engagement. Additionally, parallel search tasks revealed a larger P3 amplitude for central versus peripheral routes, suggesting significant cognitive resource allocation during tasks requiring higher attention.DiscussionThese findings underscore the nuanced role of persuasive strategies in modulating attentional resources and cognitive processing. The study offers insights into designing more effective communication messages and highlights the potential for tailored persuasion approaches to influence audience engagement and information processing, with implications for public health campaigns and beyond.
Characterizing the adult zebrafish model of Parkinson’s disease: a systematic review of dynamic changes in behavior and physiology post-MPTP administration
Authors: Razali Khairiah , Kumar Jaya , Mohamed Wael M. Y. 
Published: September 2024

IntroductionAdult zebrafish are increasingly used in Parkinson’s disease (PD) research due to their well-characterized dopaminergic system. Among the toxin-based models, the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is widely utilized to induce parkinsonism in adult zebrafish. Therefore, this review presents an overview of the procedures and the dynamic changes in behavior and physiology observed in the adult zebrafish PD model following a single intraperitoneal injection of MPTP.MethodsA systematic literature search in the PubMed and Google Scholar databases was conducted to identify relevant articles. Of the 165 articles identified, 9 were included in this review. These chosen articles are original works published before March 2024, all of which utilized adult zebrafish induced with MPTP as the model for PD. Other articles were excluded based on factors such as limited relevance, utilization of zebrafish embryos or larvae instead of adults, and variations in MPTP deliveries.ResultsStudies indicated that the ideal model entails the utilization of mixed gender zebrafish aged between 4 and 6 months from the wild-type strain. The acceptable MPTP doses ranges between 20 μg/g (lowest) and 225 μg/g (highest) and doses above 292 μg/g are lethal. Furthermore, noticeable parkinsonian symptoms appear 1 day after administration and persist for more than 1 week.DiscussionMitochondrial dysfunction precedes dopaminergic neurodegeneration within this experimental regime. A single administration of MPTP effectively induces PD in adult zebrafish. This study aids in crafting the adult zebrafish PD model, outlining the progressive behavioral and physiological changes ensuing from MPTP administration.