bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neonatal Hypopituitarism: Unusual Presentation
Authors: Abu-Libdeh Abdulsalam , Abu-Libdeh Bassam , Abdulhag Ulla 
Published: August 2017

Objective We report an infant with panhypopituitarism presenting with cholestatic jaundice, hypoglycemia, and high ferritin level.
Methods We conducted clinical and laboratory investigations, including metabolic, infectious, and hormonal evaluation.
Results Hormonal evaluation revealed panhypopituitarism (cortisol deficiency, growth hormone deficiency, and central hypothyroidism). Other causes of cholestasis were ruled out. Surprisingly, serum ferritin level was very high suggesting neonatal hemochromatosis, which was ruled out by the absence of hemosiderin deposition in buccal mucosal biopsy. Replacement therapy with glucocorticoids and L-thyroxin showed improvement of liver function tests, resolved cholestatic jaundice, and significantly decreased serum ferritin level. These findings support the assumption that thyroid hormone and cortisol affect the bile acid-independent bile flow.
Conclusion This is the first description of an infant with congenital panhypopituitarism, presenting with cholestasis, hypoglycemia, and high serum ferritin level. Panhypopituitarism should be considered in any infant who presents with cholestasis, hypoglycemia, and other manifestations of pituitary malfunction. High serum ferritin level probably reflects acute phase reaction.
Acute and Chronic Therapies in Pediatric Inflammatory Central Nervous System Diseases
Authors: Wilbur Colin , Yeh E. 
Published: August 2017

AbstractRecognition of pediatric neuroinflammatory disorders has increased in recent years, together with an increased knowledge of the immune mechanisms underlying these disorders. These insights have led to paying greater attention to the classification of these disorders, and importantly, increasing information on therapeutic interventions that may improve outcomes. Furthermore, this has occurred in the wake of the development of multiple targeted immune therapies, thus creating a complex treatment landscape. This review aims to summarize the available literature regarding acute and chronic therapies for pediatric inflammatory central nervous system (CNS) disorders. A standardized approach to the initial management of these diseases is presented.
Aktuelle Aspekte zur Prämenstruellen Dysphorischen Störung – Ein Überblick
Authors: Beddig Theresa , Kühner Christine 
Published: August 2017

ZusammenfassungIm vorliegenden narrativen Review werden aktuelle Aspekte zu Diagnostik, Häufigkeit, Ätiologie und Behandlungsstrategien der Prämenstruellen Dysphorischen Störung (PMDS) vorgestellt. Die Störung ist gekennzeichnet durch emotionale, körperliche und verhaltensmäßige Veränderungen während der prämenstruellen Phase des Monatszyklus, die mit klinisch relevantem Leiden und deutlicher Beeinträchtigung der Funktionsfähigkeit einhergehen. Aufgrund der spezifischen Leitsymptome (v. a. Affektlabilität und Gereiztheit), dem spezifischen Beschwerdeverlauf sowie der relativ hohen symptomspezifischen Stabilität wurde sie in der fünften Auflage des „Diagnostischen und Statistischen Manuals Psychischer Störungen“ (DSM-5) als eigenständige Störungsdiagnose in das Kapitel Depressive Störungen aufgenommen. Die 12-Monatsprävalenz liegt zwischen 3 und 8% bei Frauen im gebärfähigen Alter. Im deutschen Sprachraum ist das Störungsbild bislang noch unzureichend bekannt, in der Internationalen statistischen Klassifikation der Krankheiten und verwandter Gesundheitsprobleme (ICD-10) fehlt die PMDS als eigenständige Störungskategorie. Die zugrundeliegenden Mechanismen sind noch nicht zufriedenstellend geklärt, eine multifaktorielle Genese wird angenommen. Derzeit liegen noch zu wenig randomisiert-kontrollierte Studien zur PMDS vor, um eindeutige evidenzbasierte Handlungsempfehlungen geben zu können.
Internal-scope taking arguments in the information structure of deverbal nominals in Hungarian
Authors: Alberti Gábor , Farkas Judit , Szabó Veronika 
Published: August 2017

Abstract
The paper claims that the syntax of Hungarian is so extremely transparent from a pragmasemantic point of view that certain (complex-event-related) deverbal nominal constructions can have an internal information structure consisting of internal-scope taking dependents. The scope-semantic source of such an internal scope is an embedded verbal construction complemented by the nominalizer. What makes it possible for an internal information structure to be hosted is (the independent factor) that the Hungarian noun-phrase structure is (even) more flexible than was hypothesized earlier: so flexible that it can host as complex pragmasemantic hierarchies as verbal structures can. In this way, Hungarian makes it possible to express explicitly, by word order, all potential scope orders not only in verbal constructions, but even within noun phrases. We thus argue for the integration of the carthographic Split-DP (or Clausal-DP) Hypothesis into the Hungarian traditions via inserting operator layers in the Hungarian noun-phrase structure both above and below the DP-layer.
Hungarian classifier constructions, plurality and the mass–count distinction
Authors: Schvarcz Brigitta R. , Rothstein Susan 
Published: August 2017

Abstract
We argue that Hungarian has both mass and count nouns, and a plural marker which is sensitive to the distinction, as well as a system of sortal classifiers. In English, most nouns are either mass (e.g mud) or count (e.g. book), and there are only a limited number of fully flexible nouns with both mass and count forms (e.g. stone/stones). In Hungarian, however, most count nouns are flexible, and a noun like rózsa ‘rose’ is ambiguous between a mass and a count item. This results in two ways of counting: rózsa as a count noun can be directly modified by a numeral as in két rózsa ‘two roses’, but if it is a mass noun counting uses a classifier construction as in két szál rózsa.
French additive particle aussi
Authors: Benazzo Sandra , Patin Cédric 
Published: August 2017

Abstract
The goal of this study is to determine whether prosody contributes to the discrimination of meaning in sentences with the French additive particle aussi (‘also’). Previous research has highlighted the frequent use of this particle in structurally ambiguous positions, especially in spoken data, while authors diverge on their views as to the possible contribution of prosody to their disambiguation. In order to verify the role of prosody, we have run an experimental study based on a reading task: 20 native speakers were recorded while reading a set of contextualized sentences with aussi placed in both structurally ambiguous and non-ambiguous positions. The results show the presence of different types of prosodic correlates associated with aussi, but also that they are not exploited in a systematic way.
Mapping additivity through translation
Authors: Andorno Cecilia , De Cesare Anna-Maria 
Published: August 2017

Abstract
Many languages have an overabundant set of additive focus adverbs (AFAs), whose differences are mostly investigated in semantic (e.g. scalarity) or syntactic (scope phenomena and restrictions for specific domains of association) terms. The present study adopts a discourse perspective on the issue, comparing two cross-linguistic, near-equivalent AFAs (Italian anche and French aussi) in original texts and their translations in the Europarl corpus. Specifically, this study describes the relation established between the constituent in the scope of the AFA and its alternatives, which can be either co-textually available or contextually inferable. Comparing the frequencies of anche and aussi in original texts and taking into account their translation equivalents confirms important differences between these adverbs. While aussi is more restricted to the syntagmatic function of linking co-textually available alternatives in adjacent sentences, anche appears in a wider array of uses, including cases in which the identification of alternatives requires more complex inferential steps, as they are distant or even implicit to the domain of association.
Requests for here-and-now actions in Russian conversation
Authors: Bolden Galina 
Published: August 2017

Abstract
This chapter examines interactional dimensions of requests for material objects and other immediate practical actions in Russian conversation, focusing on the most common form these requests take – imperative verb constructions. Even though the Russian language has a rich variety of constructions for performing requests, imperative requests are ubiquitous across situations and settings. This predominance of imperative requests in Russian appears to be quite unique cross-linguistically, as the majority of studied languages use imperative requests less frequently and only under limited pragmatic conditions. Using video recordings of interactions between family and friends, this chapter shows that “plain” – i.e., unadorned or unelaborated – imperatives are a default or unmarked request form for here-and-now actions. This argument is supported, on the one hand, by a numerical prevalence of imperative requests across various interactional configurations, and, on the other hand, by how agreeing responses to different request constructions are produced. The analysis shows that imperative requests convey a presumption of the addressee’s compliance and availability, and request responses are designed to corroborate or reassert this presumption, enacting and renewing an expectation of willing and unquestionable assistance. Overall, the study advances our understanding of language‑ and culture-specific variations in the organization of collaboration and assistance in social interaction.
A broken promise: microbiome differential abundance methods do not control the false discovery rate
Authors: Hawinkel Stijn , Mattiello Federico , Bijnens Luc , Thas Olivier 
Published: August 2017

AbstractHigh-throughput sequencing technologies allow easy characterization of the human microbiome, but the statistical methods to analyze microbiome data are still in their infancy. Differential abundance methods aim at detecting associations between the abundances of bacterial species and subject grouping factors. The results of such methods are important to identify the microbiome as a prognostic or diagnostic biomarker or to demonstrate efficacy of prodrug or antibiotic drugs. Because of a lack of benchmarking studies in the microbiome field, no consensus exists on the performance of the statistical methods. We have compared a large number of popular methods through extensive parametric and nonparametric simulation as well as real data shuffling algorithms. The results are consistent over the different approaches and all point to an alarming excess of false discoveries. This raises great doubts about the reliability of discoveries in past studies and imperils reproducibility of microbiome experiments. To further improve method benchmarking, we introduce a new simulation tool that allows to generate correlated count data following any univariate count distribution; the correlation structure may be inferred from real data. Most simulation studies discard the correlation between species, but our results indicate that this correlation can negatively affect the performance of statistical methods.
Effectiveness of a Treatment for Impairments in Social Cognition and Emotion Regulation (T-ScEmo) After Traumatic Brain Injury: A Randomized Controlled Trial
Authors: Westerhof-Evers Herma J. , Visser-Keizer Annemarie C. , Fasotti Luciano , Schönherr Marleen C. , Vink Martie , van der Naalt Joukje , Spikman Jacoba M. 
Published: August 2017

Objective:
To evaluate the effects of a multifaceted Treatment for Social cognition and Emotion regulation (T-ScEmo) in patients with a traumatic brain injury.

Participants:
Sixty-one patients with moderate to severe traumatic brain injury randomly assigned to an experimental T-ScEmo intervention or a Cogniplus control condition.

Interventions:
T-ScEmo is a compensatory strategy training for impairments in emotion recognition, theory of mind, and social behavioral skills. Cogniplus is a computerized cognitive function training. Both interventions were given in 16 to 20 weekly 1-hour sessions.

Main Measures:
Social cognition tests and questionnaires for social behavior (self- and proxy-rated) administered at baseline, immediately posttreatment, and at 3 to 5 months of follow-up.

Results:
Compared with the Cogniplus group, the T-ScEmo group improved significantly on facial affect recognition, theory of mind, proxy-rated empathic behavior, societal participation, and treatment goal attainment, which lasted up to 5 months after treatment. At follow-up, the T-ScEmo group also reported higher quality of life and their life partners rated relationship quality to be higher than the Cogniplus group.

Conclusion:
This study shows that impairments in social cognition can be effectively dealt with by using a comprehensive treatment protocol, leading to improvements in everyday life social functioning.
Electrocorticographic Patterns in Epilepsy Surgery and Long-Term Outcome
Authors: San-Juan Daniel , Alonso-Vanegas Mario Arturo , Trenado Carlos , Hernández-Segura Natalia , Espinoza-López Dulce Anabel , González-Pérez Brenda , Cobos-Alfaro Esmeralda , Zúñiga-Gazcón Héctor , Fernández-González de Aragón María del Carmen , Hernandez-Ruiz Axel 
Published: August 2017

Purpose:
The role of intraoperative electrocorticography (iECoG) and of its patterns in epilepsy surgery have shown contradictory results. Our aim was to describe iECoG patterns and their association with outcome in epilepsy surgery.

Methods:
We retrospectively analyzed 104 patients who underwent epilepsy surgery (2009–2015) with pre- and postresection iECoG. We described clinical findings, type of surgery, preresection iECoG patterns according to Palmini et al., 1995 (sporadic, continuous, burst, and recruiting interictal epileptiform discharges—IEDs) and postresection iECoG outcome (de novo, residual, and without IEDs). The Engel scale was used to evaluate the outcome. Descriptive statistics, Kaplan-Meier, the logistic regression model, and analysis of variance tests were used.

Results:
We included 60.6% (63/104) females, with a mean age of 35 (±10.2) years at the time of epilepsy surgery. The etiologies were hippocampal sclerosis (63.5%), cavernomas (14.4%), cortical dysplasia (11.5%), and low-grade tumors (10.6%). The most common preresection iECoG pattern was sporadic IEDs (47%). Postresection iECoG patterns were de novo (55.7%), residual (27.8%), and without IEDs (16.3%). Mean follow-up was 19.2 months. Engel scale was as follows: Engel I (91 patients, 87.5%), Engel II (10 patients, 9.6%), and Engel III (three patients, 2.9%). Analysis by mixed-design analysis of variance showed a significant difference between etiology groups with a strong size effect (P = 0.021, η2 = 0.513) and also between preresection iECoG patterns (P = 0.008, η2 = 0.661).

Conclusions:
Preresection iECoG patterns and etiology influence Engel scale outcome in lesional epilepsy surgery.
Programming of neural progenitors of the adult subependymal zone towards a glutamatergic identity byNeurogenin2
Authors: Péron Sophie , Miyakoshi Leo M , Brill Monika S , Ortega Felipe , Karow Marisa , Gascón Sergio , Berninger Benedikt 
Published: August 2017

ABSTRACTWhile the adult subependymal zone (SEZ) harbors pools of distinct neural stem cells that generate different types of GABAergic interneurons, a small progenitor population in the dorsal SEZ expressesNeurog2and gives rise to glutamatergic neurons. Here we investigated whether SEZ progenitors can be programmed towards glutamatergic neurogenesis through forced expression ofNeurog2.Retrovirus-mediated expression ofNeurog2induced the glutamatergic neuron lineage markers Tbr2 and Tbr1 in cultured SEZ progenitors which subsequently differentiated into functional glutamatergic neurons. Likewise, retrovirus-mediated expression ofNeurog2in dividing SEZ progenitors within the adult SEZ induced Tbr2 and Tbr1 expression, hallmarking entry into the glutamatergic lineage alsoin vivo.Intriguingly,Neurog2-expressing progenitors failed to enter the rostral migratory stream (RMS) and instead differentiated directly within the SEZ or the adjacent striatum. In sharp contrast, lentivirus-mediated postmitotic expression ofNeurog2failed to reprogram early SEZ neurons, which instead maintained their GABAergic identity and migrated along the RMS towards the olfactory bulb. Thus, our data show thatNeurog2can program SEZ progenitors towards a glutamatergic identity, but fails to reprogram their postmitotic progeny.Summary statementOur study identifies a critical developmental time window during which progenitors of the adult subependymal zone, specified for generating GABAergic neurons, can be reprogrammed towards glutamatergic neurogenesis.
Linear relationship between peak and season-long abundances in insects
Authors: Onufrieva Ksenia S. , Onufriev Alexey V. 
Published: August 2017

AbstractAn accurate quantitative relationship between key characteristics of an insect population, such as season-long and peak abundances, can be very useful in pest management programs. To the best of our knowledge, no such relationship yet has been established.Here we establish a predictive linear relationship between insect catchMpwduring the week of peak abundance, the length of seasonal flight period,F(number of weeks) and season-long cumulative catch (abundance)A=0.41MpwF. The derivation of the equation is based on several general assumptions, and does not involve fitting to experimental data, which implies generality of the result. A quantitative criterion for the validity of the model is presented.The equation was tested using extensive data collected on captures of male gypsy mothsLymantria dispar(L.) (Lepidoptera: Erebidae) in pheromone-baited traps during 15 years.The model was also tested using trap catch data for two species of mosquitoes,Culex pipiens(L.) (Diptera: Culicidae) andAedes albopictus(Skuse) (Diptera: Culicidae), in Gravid and BG-sentinel mosquito traps, respectively.The simple, parameter-free equation approximates experimental data points with relative error of 13% andR2= 0.997, across all of the species tested.For gypsy moth, we also related season-long and weekly trap catches to the daily trap catches during peak flight.We describe several usage scenarios, in which the derived relationships are employed to help link results of small-scale field studies to the operational pest management programs.
Growth of research journals in India during last decade (2005-2014): an overview
Authors: Pandita Ramesh , Koul Meenakshi , Singh Shivendra 
Published: August 2017

Purpose
The purpose of this study is to reflect a growing trend toward the introduction of new research journals in India. The study focuses on the number of journals introduced in India during the past decade, namely, for the period 2005-2014. Some of the key aspects analyzed include year-wise distribution of journals introduced, cumulative and annual corresponding growth of newly introduced journals, publishing form of journals, namely, online, print and hybrid. Some other aspects studied include distribution of journals on the basis of language, periodicity, state, etc. for both online and print journals.

Design/methodology/approach
To undertake the present study, data were retrieved from the official website of the National Science Library, New Delhi, and the analysis is based on the number of ISSN numbers issued by the National Science Library New Delhi during the period of study.

Findings
A total of 15,631 research journals were introduced in India from 2005 through 2014. Compared to 4,954 (31.69 per cent) online journals, 10,614 (67.90 per cent) print journals were introduced in India during the past decade, depicting print as the larger medium of journal publishing in India. During the period of study, research journals in India grew annually at 31.44 per cent. New Delhi, Maharashtra and Uttar Pradesh emerged as the three leading research journal publishing states of the country, while 82.86 per cent journals are published in English language and a maximum 32.52 per cent journals are published on a quarterly basis.

Originality/value
The study is first of its kind undertaken in India.
Measuring the impact: Springer Book Archives at Melbourne
Authors: Kent Philip Gregory 
Published: August 2017

Purpose
The purpose of this paper is to examine usage trends during the first four years of the implementation of the Springer Book Archives (SBA) at the University of Melbourne. The paper assesses the benefits of the SBA against perceptions at the time of purchase and seeks to evaluate the long-term value of the purchase.

Design/methodology/approach
The methodology included a literature search to identify issues in the adoption of large backlists of ebooks, examination of detailed usage data supplied in COUNTER complaint spreadsheets and tables by Springer, validating findings with librarians and academics and positing next steps.

Findings
Usage of ebooks, like other electronic resources, is difficult to predict. Resources expected to be used, may not be and vice versa. Access to large aggregations of electronic content creates new opportunities for teaching and research, additional economies and benefits, as well as unexpected outcomes.

Research limitations/implications
Detailed data on user profiles were not available and an evaluation of user perceptions was not possible at this time.

Originality/value
The literature review suggests that this is the only published study of institutional usage of the SBA at this time.
The effectiveness of matching sales influence tactics to consumers’ avoidance versus approach shopping motivations
Authors: Guo Wenxia , Main Kelley 
Published: August 2017

Purpose
Adaptive selling can help build positive relationships between salespeople and consumers. The literature shows that consumers respond positively to salespeople under approach but not avoidance motivations. This paper aims to demonstrate a circumstance under which consumers with avoidance motivations can also respond positively, something not previously shown in the literature.

Design/methodology/approach
This research paper uses three experimental between-subject designs to test hypotheses.

Findings
The current research identifies appropriate sales influence tactics (e.g. a customer-autonomy-oriented or a loss-avoidance-oriented influence tactic) where consumers with avoidance motivations can also respond to sales agents positively by the evidence of higher purchase intentions. In addition, this research shows that consumers with approach motivations may not always respond positively to salespeople. Further, goal facilitation appraisals of the salespeople serve as a mechanism between consumers’ shopping motivations and their behavioral responses (e.g. purchase intentions).

Originality/value
First, while the previous literature demonstrates that approach motivations generally lead to more positive effects (Elliot and Trash, 2002), this research indicates that avoidance motivations can also have positive effects, which is a finding that has not been demonstrated in the literature thus far. Second, this research identifies goal facilitation appraisals as one underlying process that explains the interactive effect between matching influence tactics and consumers’ approach/avoidance motivations when shopping. Third, the authors integrate regulatory focus theory by using gain- or loss-avoidance-oriented sales influence tactics to match approach and avoidance motivations.