bluuebunny/crossref_metadata_2025_split huggingface dataset:
Standardized Criteria for Palliative Care Consultation on a Solid Tumor Oncology Service Reduces Downstream Health Care Use
Authors: Adelson Kerin , Paris Julia , Horton Jay R. , Hernandez-Tellez Lorena , Ricks Doran , Morrison R. Sean , Smith Cardinale B. 
Published: March 2017

Purpose: Hospitalized patients with advanced cancer have a high symptom burden and need for support. Integration of palliative care (PC) improves symptom control and decreases unwanted health care use, yet many patients are never offered these services. In 2016, ASCO called for incorporation of PC into oncologic care for all patients with metastatic cancer. To improve the quality of cancer care, we developed standardized criteria, or triggers, for PC consultation on the inpatient solid tumor service. Methods: Patients were eligible for this prospective cohort study if they met at least one of the following eligibility criteria: had an advanced solid tumor; prior hospitalization within 30 days; hospitalization > 7 days; and active symptoms. During the intervention, patients who met the criteria received automatic PC consultation. Results: When we compared patients in the intervention group with control subjects, there were increases in PC consultations (19 of 48 [39%] to 52 of 65 [80%]; P ≤ .001) and hospice referrals (seven of 48 [14%] to 17 of 65 [26%]; P = .03), and there were declines in 30-day readmission rates (17 of 48 [35%] to 13 of 65 [18%]; P = .04) and receipt of chemotherapy after discharge (21 of 48 [44%] to 12 of 65 [18%]; P = .03). There was an overall increase in support measures following discharge ( P = .004). Length of stay was unaffected. Conclusion: To our knowledge, this is the first study to demonstrate that among patients with advanced cancer admitted to an inpatient oncology service, the standardized use of triggers for PC consultation is associated with substantial impact on 30-day readmission rates, chemotherapy following discharge, hospice referrals, and use of support services following discharge. Expansion of this model to other hospitals and health systems should improve the value of cancer care.
A Perioperative Smoking Cessation Intervention With Varenicline, Counseling, and Fax Referral to a Telephone Quitline Versus a Brief Intervention: A Randomized Controlled Trial
Authors: Wong Jean , Abrishami Amir , Riazi Sheila , Siddiqui Naveed , You-Ten Eric , Korman Jennifer , Islam Sazzadul , Chen Xin , Andrawes Maged S. M. , Selby Peter , Wong David T. , Chung Frances 
Published: March 2017

BACKGROUND:
The effectiveness of perioperative interventions to quit smoking with varenicline has not been compared with brief interventions. Our objective was to determine the efficacy of a comprehensive smoking cessation program versus a brief intervention for smoking cessation.

METHODS:
In this prospective, multicenter study, 296 patients were randomized to participate in a smoking cessation program (one 10- to 15-minute counseling session, pharmacotherapy with varenicline, an educational pamphlet, and a fax referral to a telephone quitline); or brief advice and self-referral to a telephone quitline. The primary outcome was the 7-day point prevalence (PP) abstinence at 12 months after surgery. Secondary outcomes included abstinence at 1, 3, and 6 months. Multivariable generalized linear regression was used to identify independent variables related to abstinence.

RESULTS:
The 7-day PP abstinence for the smoking cessation program versus brief advice group was 42.4% vs 26.2% (relative risk [RR], 1.62; 95% confidence interval [CI], 1.16–2.25; P = .003) at 12 months. The 7-day PP abstinence at 1, 3, and 6 months was higher in the smoking cessation group versus the brief advice group: 45.7% vs 25.5% (RR, 1.79; 95% CI, 1.29–2.49; P < .001), 46.4% vs 26.9% (RR, 1.72; 95% CI, 1.25–2.37; P< .001), and 45.0% vs 26.2% (RR, 1.72; 95% CI, 1.24–2.38; P < .001), respectively. Participating in the smoking cessation group predicted abstinence at 12 months (RR, 1.58; 95% CI, 1.12–2.21; P = .0087).

CONCLUSIONS:
A perioperative smoking cessation program with counseling, pharmacotherapy with varenicline, an educational pamphlet, and a fax referral to a quitline increased abstinence from smoking 1, 3, 6, and 12 months after surgery versus a brief intervention.
The Heat Content for Nonlocal Diffusion with Non-singular Kernels
Authors: Mazón Jose Manuel , Rossi Julio D. , Toledo Julián 
Published: March 2017

Abstract
We study the behavior of the heat content for a nonlocal evolution problem.We obtain an asymptotic expansion for the heat content of a set D, defined as

ℍ
D
J

⁢

(
t
)

:=

∫
D

u
⁢

(
x
,
t
)

⁢

𝑑
x

${\mathbb{H}_{D}^{J}(t):=\int_{D}u(x,t)\,dx}$

, with u being the solution to

u
t

=

J
∗
u

-
u

${u_{t}=J\ast u-u}$

withinitial condition

u
0

=

χ
D

${u_{0}=\chi_{D}}$

. This expansion is given in terms of geometric values of D. As a consequence, we obtain that

ℍ
D
J

⁢

(
t
)

=

|
D
|

-

P
J

⁢

(
D
)

⁢
t

+

o
⁢

(
t
)

${\mathbb{H}^{J}_{D}(t)=\lvert D\rvert-P_{J}(D)t+o(t)}$

as

t
↓
0

${t\downarrow 0}$

.We also recover the usual heat content for the heat equation when we rescale the kernel J in an appropriate way.Finally, we also find an asymptotic expansion for the nonlocal analogous to the spectral heat content that is defined as before but considering

u
⁢

(
x
,
t
)

${u(x,t)}$

a solution to the equation

u
t

=

J
∗
u

-
u

${u_{t}=J\ast u-u}$

inside D with

u
=
0

${u=0}$

in

ℝ
N

∖
D

${\mathbb{R}^{N}\setminus D}$

andinitial condition

u
0

=

χ
D

${u_{0}=\chi_{D}}$

.
Design of Condition-Based Decision Support System for Preventive Maintenance
Authors: Galamboš Róbert , Galambošová Jana , Rataj Vladimír , Kavka Miroslav 
Published: March 2017

Abstract
Presented paper deals with the topic of preventive maintenance. A decision support system was designed, incorporating historical as well as forecast information to calculate the time remaining to preventive maintenance. The designed system optimizes maintenance costs without any further investment and running costs. An algorithm of the designed system is introduced and a case study of its implementation is described in the paper.
Field Performance and Genetic Fidelity of Micropropagated Plants of Coffea canephora (Pierre ex A. Froehner)
Authors: Muniswamy Bychappa , Kosaraju Bharathi , Mishra Manoj Kumar , Yenugula Raghuramulu 
Published: March 2017

AbstractThis study was conducted to compare the growth and yield of one of the commercial hybrid coffee cultivars (Coffea congensis x Coffea canephora) of robusta coffee established from somatic embryogenesis as well as conventional seedlings. Results indicated no statistically significant differences in the growth pattern or the cumulative yield between the somatic embryogenesis derived plants and the seedlings. The genetic fidelity of somatic embryogenesis derived plants and the mother plant was tested using sequence related amplified polymorphism (SRAP) markers. A total of 24 SRAP primers were employed for DNA analysis which produced a total of 153 clear, distinct and reproducible amplicons of variable size. Out of 24 SRAP primers, 9 primers produced amplification patterns which are identical between the mother plants and plants derived from somatic embryogenesis. Cluster analysis revealed more than 95% genetic similarity between the somatic embryogenesis derived plants and the mother plants indicating a high degree of genetic fidelity. The present study clearly demonstrates the usefulness of SRAP markers in genetic fidelity analysis of coffee.
Foliage maturity of Quercus ilex affects the larval development of a Croatian coastal population of Lymantria dispar (Lepidoptera: Erebidae)
Authors: Lukić Ivan , Schafellner Christa , Lakatos Ferenc , Lacković Nikola , Mrmić Sanja , Pernek Milan 
Published: March 2017

AbstractGypsy moth (Lymantria dispar) is one of the most important forest pests in the world. Numerous previous studies focused only on different host tree species, but small number of them on foliage age. Since recent genetic analyses showed that there are significant differences between Croatian continental and coastal population we investigated coastal population since there was no previous research. For this research juvenile and mature foliage of Holm oak (Quercus ilex) was used. Larval development was investigated in two laboratory experiments. One experiment involved rearing trials consisting of 50 individual larvae per treatment while a parallel experiment investigated gregarious feeding conditions using 120 larvae in a rearing treatment. Larval mortality was lower and development time shorter for individuals reared on juvenile foliage. High pupation success in both the individual and group rearing experiment for larvae reared on juvenile foliage was also observed. To conclude, our results showed high mortality, poor larval development and low pupation success in larvae reared on mature foliage. This research is significant because in the aspect of ongoing climate changes there is a possibility that gypsy moth will move to the north and shift its distribution by expanding into new climatic area.
Splitting theorems for Poisson and related structures
Authors: Bursztyn Henrique , Lima Hudson , Meinrenken Eckhard 
Published: March 2017

Abstract
According to the Weinstein splitting theorem, any Poisson manifold is locally, near any given point, a product of a symplectic manifold with another Poisson manifold whose Poisson structure vanishes at the point. Similar splitting results are known, e.g., for Lie algebroids, Dirac structures and generalized complex structures. In this paper, we develop a novel approach towards these results that leads to various generalizations, including their equivariant versions as well as their formulations in new contexts.
Comparative investigation of physical, mechanical and thermomechanical characterization of dental composite filled with nanohydroxyapatite and mineral trioxide aggregate
Authors: Meena Anoj , Mali Harlal Singh , Patnaik Amar , Kumar Shiv Ranjan 
Published: March 2017

AbstractThis study presents comparative investigation of adding nanohydroxyapatite (HA) (5–20 wt.%) and mineral trioxide aggregate (MTA) (5–20 wt.%) on the physical, mechanical and thermomechanical characterization of dental composite. The performances of both experimental composites were assessed through various physical, mechanical and thermomechanical tests such as void content test, microhardness test, compressive strength test, dynamic mechanical analysis and thermogravimetric analysis. The result of experiment indicated that the addition of 5 wt.% of HA increased the water sorption, hardness and compressive strength by 50.47%, 13.46% and 62.35%, respectively, whereas the addition of 5 wt.% of MTA increased the water sorption, hardness and compressive strength by 19.23%, 100% and 5.44%, respectively. Dynamic mechanical analysis results revealed that the addition of 5 wt.% HA increased the storage modulus by 10.21%, whereas the addition of 5 wt.% of MTA decreased the storage modulus by 11.79%. The filler HA proved to be better choice in term of thermal stability behavior as compare to MTA filler.
CHAID Decision Tree: Methodological Frame and Application
Authors: Milanović Marina , Stamenković Milan 
Published: March 2017

Abstract
Technological advancement across human activities has brought about accelerated generation of huge amounts of data. Consequently, researchers are faced with the problem how to determine adequate ways of turning the available data mass into useful knowledge. Data analysis adapted to these changes when data mining was developed as an approach to data analysis from different perspectives which reveals significant hidden regularities. This paper presents conceptual characteristics of decision tree, an important data mining method which is, due to its explorative nature, exceptionally suitable for detection of data structure when analysing various problem situations. The empirical section of the paper demonstrates applicative characteristics of this method using CHAID algorithm in leadership studies: an interdependence of selected personal characteristics and the manager’s leadership style has been investigated. The aim of the paper is to develop a classification model for identification of the dominant leadership style. The study was conducted on the sample of 417 managers of privately owned small-sized enterprises in Serbia, using a specially designed questionnaire. The classification model identified the set of six statistically significant personal characteristics as predictors of dominant leadership style.
Research Note. The wild water-rats and their relevance in the context of schistosomiasis mansoni in Brazil: what we know and recommendations for further research
Authors: Miranda G. S. , Miranda B. S. , Rodrigues J. G. M. , Lira M. G. S. , Nogueira R. A. , Viegas-Melo D. , Silva-Souza N. 
Published: March 2017

Summary
Schistosomiasis is a parasitic and endemic disease in several parts of the world. Its mortality rate reaches alarming proportions, which makes emergency the control of this disease. In Brazil, only the species Schistosoma mansoni was adapted to the climatic conditions and to the presence of appropriate hosts. This species shows a life cycle involving mollusks Biomphalaria spp. and humans. However, it has been shown that wild rodents with semi-aquatic habits are capable to establish a productive infection of this parasite. In addition, they are likely also to be capable to spread the disease in endemic areas. Due to the selective pressure exerted by the successive infections in these animals, we may be watching the development of a new strain of the parasite, which is not yet fully defined and understood. With the intention of directing new studies to this problem, we tried to establish main lines of research to demonstrate the real importance of these wild rodents in the epidemiology of schistosomiasis mansoni in Brazil.
Research Note. Occurrence of gastrointestinal helminths in commensal rodents from Tabasco, Mexico
Authors: Cigarroa-Toledo N. , Santos-Martinez Y. De Los , Zaragoza-Vera C. V. , Garcia-Rodriguez M. M. , Baak-Baak C. M. , Machain-Williams C. , Garcia-Rejon J. E. , Panti-May J. A. , Torres-Chable O. M. 
Published: March 2017

Summary
The aim of this study was to determine the prevalence and species composition of helminths in commensal rodents captured inside private residences in the city of Villahermosa in Tabasco, Mexico. Trapping was performed at each house for three consecutive nights from October to December 2015. Fifty commensal rodents were captured: 23 Rattus norvegicus, 16 Mus musculus and 11 Rattus rattus. Rodents were transported alive to the laboratory and held in cages until they defecated. Feces were analyzed for helminth eggs using the Sheather’s flotation technique. The overall prevalence of helminths in rodents was 60 %: R. norvegicus was more likely to be parasitized (87.0 %) than R. rattus (63.6 %) and M. musculus (18.8 %). Eggs from at least 13 species of helminths were identified: Hymenolepis diminuta, Rodentolepis nana, Moniliformis moniliformis, Heligmosomoides polygyrus, Heterakis spumosa, Mastophorus muris, Nippostrongylus brasiliensis, Strongyloides ratti, Syphacia obvelata, Syphacia muris, Toxocara sp., Trichosomoides crassicauda, and Trichuris muris. This is the first study to report the presence of H. polygyrus, S. ratti and T. crassicauda in commensal rodents in Mexico. In conclusion, our results suggest that helminths commonly infect commensal rodents in Villahermosa and therefore rodents present a health risk to inhabitants in this region.
Mutation of N-linked glycosylation in EpCAM affected cell adhesion in breast cancer cells
Authors: Liu Xue , Gao Jiujiao , Sun Yan , Zhang Dandan , Liu Tingjiao , Yan Qiu , Yang Xuesong 
Published: March 2017

Abstract
Epithelial cell adhesion molecule (EpCAM) expression is elevated in breast cancer tissue, and correlates with the cancer metastasis and cell adhesion. Although EpCAM glycosylation is supposed to be associated with its function, the contribution of N-glycosylation to its function remains unclear. Here we analyzed cell adhesion ability of EpCAM in breast cancer cells. The results showed that EpCAM expression was associated with cell adhesion and N-glycosylation mutation of EpCAM decreased adhesion capacity. N-glycosylation mutation of EpCAM was correlated with lower levels of integrin β1 and fibronectin. We also found that effect of N-glycosylation of EpCAM on cell adhesion was regulated via FAK/Akt/Gsk-3β/β-catenin signaling pathway, which further adjusted MMP2/9 expression and activities. Our studies identified the characteristics and function of EpCAM glycosylation sites on breast cancer cell adhesion. These data could potentially clarify molecular regulation of EpCAM by N-glycosylation and intensify our understanding of the utility of glycosylated EpCAM as a target for breast cancer therapy.
Mechanisms and strategies of papillomavirus replication
Authors: McBride Alison A. 
Published: March 2017

Abstract
Animal and human papillomaviruses (HPVs) replicate persistently in specific types of stratified epithelia of their host. After the initial infection, the viral genome replicates at low levels in the dividing cells of the epithelium, and these cells form a reservoir of infection that can last for decades. When the infected cells differentiate, viral genomes replicate to high levels to form progeny virus that is released from the surface of the epithelium. This complex life cycle requires several different modes of viral DNA replication, but papillomaviruses are masters at hijacking key cellular processes to facilitate their own reproduction.
Reliability and Validity of a New Test of Agility and Skill for Female Amateur Soccer Players
Authors: Kutlu Mehmet , Yapici Hakan , Yilmaz Abdullah 
Published: March 2017

Abstract
The aim of this study was to evaluate the Agility and Skill Test, which had been recently developed to assess agility and skill in female athletes. Following a 10 min warm-up, two trials to test the reliability and validity of the test were conducted one week apart. Measurements were collected to compare soccer players’ physical performance in a 20 m sprint, a T-Drill test, the Illinois Agility Run Test, change-of-direction and acceleration, as well as agility and skill. All tests were completed following the same order. Thirty-four amateur female soccer players were recruited (age = 20.8 ± 1.9 years; body height = 166 ± 6.9 cm; body mass = 55.5 ± 5.8 kg). To determine the reliability and usefulness of these tests, paired sample t-tests, intra-class correlation coefficients, typical error, coefficient of variation, and differences between the typical error and smallest worthwhile change statistics were computed. Test results showed no significant differences between the two sessions (p > 0.01). There were higher intra-class correlations between the test and retest values (r = 0.94–0.99) for all tests. Typical error values were below the smallest worthwhile change, indicating ‘good’ usefulness for these tests. A near perfect Pearson correlation between the Agility and Skill Test (r = 0.98) was found, and there were moderate-to-large levels of correlation between the Agility and Skill Test and other measures (r = 0.37 to r = 0.56). The results of this study suggest that the Agility and Skill Test is a reliable and valid test for female soccer players and has significant value for assessing the integrative agility and skill capability of soccer players.
Investigation of the role of α-lipoic acid on fatty acids profile, some minerals (zinc, copper, iron) and antioxidant activity against aluminum-induced oxidative stress in the liver of male rats
Authors: Sahin Zafer , Ozkaya Ahmet , Yilmaz Okkes , Yuce Abdurrauf , Gunes Mehmet 
Published: March 2017

Abstract

Background:
We have investigated the effects of α-lipoic acid (LA), a powerful antioxidant, on the fatty acid (FA) profiles, aluminum accumulation, antioxidant activity and some minerals such as zinc, copper and iron against aluminum chloride (AlCl3)-induced oxidative stress in rat liver.

Methods:
Twenty-eight male Wistar rats were divided into four groups as control, LA, AlCl3 and LA+AlCl3. For 30 days, LA was intraperitoneally administrated (50 mg/kg) and AlCl3 was given via orogastric gavage (1600 ppm) every other day.

Results:
AlCl3-treated animals exhibited higher hepatic malondialdehyde concentration and lower glutathione peroxidase and catalase activity, whereas these alterations were restored by the LA supplementation. Total saturated FA of the AlCl3-treated group was higher than the LA supplementation groups. Moreover, total unsaturated FA level of the LA+AlCl3 group was higher than the AlCl3-treated group. Hepatic zinc level of the AlCl3-treated group was lower than the control group, whereas it was higher in the LA and the LA+AlCl3 groups. Hepatic copper levels did not significantly change in the experimental groups. Iron level was lower in the LA and LA+AlCl3 groups compared with the AlCl3-treated group. Moreover, the liver Al concentration was found to be lower in the LA and LA+AlCl3 groups compared to the AlCl3 group.

Conclusions:
These results indicate that AlCl3 treatment can induce oxidative stress in the liver. LA supplementation has a beneficial effect on the AlCl3-induced alterations such as high lipid peroxidation, Al accumulation, FA profile ratios and mineral concentrations.
Protective effect of Moringa oleifera oil against HgCl2-induced hepato- and nephro-toxicity in rats
Authors: Abarikwu Sunny O. , Benjamin Sussan , Ebah Sunday Godspower , Obilor Godbless , Agbam Goodluck 
Published: March 2017

Abstract:

Background:
Various parts of the Moringa oleifera (M. oleifera) tree are widely accepted to have ameliorative effects against metal toxicity. In the present study, M. oleifeira oil (MO) was tested against HgCl2-induced tissue pathologies and oxidative stress.

Methods:
Male Wistar rats were administered MO (1.798 mg/kg p.o.) or HgCl2 (5 mg/kg body wt) alone or in combination (5 mg/kg HgCl2+1.798 mg/kg MO p.o.) three times per week for 21 days. After exposure and treatment periods, rats were sacrificed; blood collected and the oxidative status of the liver and kidney homogenates were evaluated.

Results:
In the liver, malondialdehyde (MDA) level, glutathione (GSH), and superoxide dismutase (SOD) activities were higher whereas catalase (CAT) activity was lower in the HgCl2 group than in the control group. In the kidney, MDA level, SOD, and CAT activities were higher whereas GSH activity was unchanged in the HgCl2 group compared to the control group. In the liver, MDA level, SOD, and CAT activities were lower in the HgCl2+MO group than in the HgCl2 group. In the kidney, MDA level, SOD and CAT activities were lower in the HgCl2+MO than in the HgCl2 group. Furthermore, Hg-induced increases in creatinine and bilirubin levels as well as the increase in γ-glutamyl transferase, lactate dehydrogenase, and alkaline phosphatase activities were attenuated in the combine exposure group and the animals showed improvement in the histology of the liver and kidney.

Conclusions:
MO decreased the negative effects of Hg-induced oxidative stress in rats.