bluuebunny/crossref_metadata_2025_split huggingface dataset:
Left atrial volume assessed by echocardiography identifies patients with high risk of adverse outcome after acute myocardial infarction
Authors: Tangen Jorun , Nguyen Thuy Mi , Melichova Daniela , Klaeboe Lars Gunnar , Forsa Marianne , Andresen Kristoffer , Wazzan Adrien Al , Lie Oyvind , Kizilaslan Fatih , Haugaa Kristina , Skulstad Helge , Brunvand Harald , Edvardsen Thor 
Published: October 2024

Abstract
Background
The left atrial (LA) volume has been demonstrated to be an important predictor of adverse outcome in patients with various cardiac conditions, including acute myocardial infarction (AMI). However, new treatment strategies in patients with AMI have led to better patient outcomes. We hypothesised that increased LA size could still predict mortality in patients with AMI despite improved treatment strategies.

Methods
We included patients with AMI in a prospective multicenter cohort study and the study patients were enrolled from 2014 to 2022. We recorded echocardiographic and clinical data during their index hospitalisation. Indexed LA volume (LAVi) was assessed in all patients and was used as a continuous variable in the univariate and multivariate Cox regression analysis. The study took place over a period of five years and median follow-up time was 3.8 years (range 3.1 to 5.0 years). The primary study outcomes were all-cause mortality and major adverse cardiac events (MACE). MACE was defined as hospital readmission due to myocardial infarction, cardiac arrest, stroke, heart failure, or onset of new atrial fibrillation.

Results
We included 487 patients (69 ± 12 years old, 26% female) with AMI. During the follow-up period all-cause mortality was 50 (10.3%) and patients who reached the primary outcomes were 153 (31.4%). The deceased patients had higher LAVi compared to survivors (40.0 ± 12.9 mL/m2 vs. 29.7 ± 11.2 mL/m2, p < 0.001). Factors associated with all-cause mortality and MACE were age, year of enrollment, left ventricular (LV) ejection fraction, LV global longitudinal strain (GLS), LV filling pressure, moderate or severe mitral regurgitation and LAVi. GLS and EF were segregated into two distinct models due to their moderately high correlation (r = 0.57, p < 0.001). LAVi remained as an independent echocardiographic predictor of primary outcomes after adjusting for the covariates above in two separates multivariable Cox regression models (hazard ratio 1.02/1.02 mL/m2 [95% CI 1.01–1.03/1.01–1.03], p = 0.006/0.003).

Conclusions
Our study demonstrated that LA dilatation is an independent echocardiographic predictor of mortality and MACE in patients with AMI despite improved treatment strategies. This finding highlights the potential of using LAVi as a marker for prognostication in these patients.
Lou's Men
Authors: Ojeda-Sagué Gabriel 
Published: October 2024

Abstract
This article proposes that the personal writing of gay trans activist and diarist Lou Sullivan represents an erotic theoretical project akin to Leo Bersani's “homo-ness,” which Bersani describes as gayness's capacity to “manifest not the limits but the inestimable value of relations of sameness.” Sullivan's rigorous interlacing of gender and sexuality is founded on a desire for sameness, an eroticized recognition of his developing selfhood in the men he loves. In framing Sullivan's work with Bersani, this article argues that Bersani's framework of homo-ness is limited by its conceptual basis in genital parallel, creating an inability to speak to trans sexuality. Sullivan's writing, on the other hand, founds relations of sameness between himself and the gay men he desired in a conceptual architecture that understands gayness as an already trans position. In close reading Sullivan's diaries and personal correspondence, alongside artifacts of their reception by contemporary gay trans artists, this article substantiates a sense of Sullivan as a kind of sex symbol for the enfolding of gay and trans erotic worlds in the desire for sameness. Such an analysis allows gay and trans studies to speak to each other anew on the question, What is this same in same-sex sexuality?
Subthalamic Nucleus Deep Brain Stimulation for Meige Syndrome: Long-Term Outcomes and Analysis of Prognostic Factors
Authors: Zheng Wentao , Hao Qingpei , Chen Xi , Liu Yezu , Zhang Zihao , Li Zhangyu , Mao Jianyao , Zhou Liwei , Chen Sifang , Tan Guowei , Liu Ruen 
Published: October 2024

BACKGROUND AND OBJECTIVES:
The aim of this study was to explore the impacts of subthalamic nucleus deep brain stimulation (STN-DBS) on both motor and nonmotor symptoms in individuals with Meige syndrome, as well as further investigates prognostic factors for long-term postoperative outcomes.

METHODS:
We retrospectively reviewed a consecutive cohort of patients with intractable Meige syndrome who underwent STN-DBS at our center from January 2016 to July 2023. Motor function, quality of life, neuropsychological status, and mood state were evaluated with standardized scales at baseline and every 3 to 6 months thereafter. Univariate and multivariate linear regression analyses were used to determine independent risk factors that affect long-term motor function after STN-DBS.

RESULTS:
Fifty-five patients were ultimately analyzed with a mean follow-up of 62.1 ± 25.7 months. At the final postoperative assessment, movement and disability scores of the Burke-Fahn-Marsden Dystonia Rating Scale demonstrated improvements of 61% (P < .001) and 57% (P < .001), respectively. Postoperative scores on the 36-item Short-Form General Health Survey showed significant improvement from baseline. Global cognitive function and neuropsychological status remained stable during continuous neurostimulation. Multivariate linear regression analysis revealed that longer disease duration (standardized β coefficient = −0.294, 95% CI −0.039 to −0.007, P = .006), older age at surgery (standardized β coefficient = −0.382, 95% CI −0.014 to −0.004, P = .001), and smaller volume of tissue activated within the sensorimotor subregion of STN (standardized β coefficient = 0.309, 95% CI 0.001-0.004, P = .004) were independently correlated with poorer long-term motor performance.

CONCLUSION:
Bilateral STN-DBS is an effective, safe, and promising treatment option for Meige syndrome, which can improve motor function and quality of life without cognitive and mood side effects. Early diagnosis, prompt intervention, and accurate lead placement in the dorsolateral STN are crucial to optimize long-term therapeutic outcomes.
Safety, Sequelae, and Efficacy of Nerve Root Clipping in Patients With Spontaneous Spinal Cerebrospinal Fluid Leaks
Authors: El Rahal Amir , Haupt Benedikt , Wolf Katharina , Blass Bianca , Vasilikos Ioannis , Overstijns Manou , Shah Mukesch Johannes , Lützen Niklas , Urbach Horst , Häni Levin , Fung Christian , Beck Jürgen , Volz Florian 
Published: October 2024

BACKGROUND AND OBJECTIVES:
Spinal cerebrospinal fluid (CSF) leaks may cause a myriad of clinical symptoms, the most common being orthostatic headache. Lateral leaks (Type II) and direct CSF-venous fistulas (Type III) are a subgroup of spinal CSF leaks, representing about 1/3 of spinal CSF leaks. This study aimed to analyze the risk and efficacy of nerve root clipping in patients with Type II and Type III CSF leaks.

METHODS:
All consecutive patients with Type II and Type III CSF fistulas treated with nerve root clipping at our institution from May 2018 to December 2022 were included. Patients were evaluated for postoperative sensory motor deficits and neuropathic pain using the “Douleur Neuropathique 4” questionnaire, and the outcome was evaluated using the “Patient Global Impression of Change” and the return-to-work rate.

RESULTS:
A total of 40 patients were included, and the mean follow-up time was 22 months. According to the Patient Global Impression of Change, significant symptoms improvement was reported in 85% of patients. Over 87% of patients returned to work fully or partially. One patient experienced a low-grade motor deficit after T1-nerve root clipping. 2.5% of patients developed postoperative neuropathic pain requiring medical treatment under which they fully improved. Over 80% of patients developed dermatomal hypoesthesia, with no reported effect on quality of life.

CONCLUSION:
The surgical strategy of noneloquent nerve root clipping shows favorable outcomes and return-to-work rates. There are instances of neuropathic pain and dermatomal hypoesthesia with no significant morbidity. Despite the favorable outcome and low recurrence rate, nerve root-sparing surgical techniques should be further explored.
"DIGITAL" TEACHER: NEW ROLES, FUNCTIONS AND COMPETENCES
Authors: Kulikova Tatyana I. 
Published: October 2024

Background. The development of digital technologies is one of the priority tasks of modern education, a crucial step in improving the quality of learning and teaching and transforming the role of the teacher in the conditions of digitalisation of education.
The purpose of the research presented in the article is to describe the qualitative changes in the professional activity of teachers and to consider the "digital" roles and digital competence of teachers based on the data of questionnaire survey of teachers working in profile psycho-pedagogical classes in the city of Tula and Tula region.
Materials and methods. The methodological basis of the empirical study is the competence approach, in particular, digital competence. The main conceptual documents regulating the development of digital education are the national programme "Digital Economy of the Russian Federation" and the priority project "Modern Digital Educational Environment in the Russian Federation". In the course of the empirical study, the questionnaire method was applied.
Results. Theoretical analysis allowed us to state that in modern conditions the professional activity of a teacher undergoes qualitative changes. In the conditions of digitalisation of education, the school needs a multi-profile professional with digital literacy and competence. The questionnaire survey of teachers working in psycho-pedagogical classes conducted in the course of the empirical study revealed the teachers' adherence to the traditional roles of a mentor and an organiser of the learning process and the formation of competencies in the field of integrative activity (a teacher is an integrator of students' knowledge, skills and abilities). The presented analytical and empirical data are based on modern Russian and foreign experience and take into account the specifics of the Tula region.
Implant design influences the joint-specific outcome after total knee arthroplasty
Authors: Clement Nick , MacDonald Deborah J. , Hamilton David F. , Gaston Paul 
Published: October 2024

AimsThe aims were to assess whether joint-specific outcome after total knee arthroplasty (TKA) was influenced by implant design over a 12-year follow-up period, and whether patient-related factors were associated with loss to follow-up and mortality risk.MethodsLong-term follow-up of a randomized controlled trial was undertaken. A total of 212 patients were allocated a Triathlon or a Kinemax TKA. Patients were assessed preoperatively, and one, three, eight, and 12 years postoperatively using the Oxford Knee Score (OKS). Reasons for patient lost to follow-up, mortality, and revision were recorded.ResultsA total of 94 patients completed 12-year functional follow-up (62 females, mean age 66 years (43 to 82) at index surgery). There was a clinically significantly greater improvement in the OKS at one year (mean difference (MD) 3.0 (95% CI 0.4 to 5.7); p = 0.027) and three years (MD 4.7 (95% CI 1.9 to 7.5); p = 0.001) for the Triathlon group, but no differences were observed at eight (p = 0.331) or 12 years’ (p = 0.181) follow-up. When assessing the OKS in the patients surviving to 12 years, the Triathlon group had a clinically significantly greater improvement in the OKS (marginal mean 3.8 (95% CI 0.2 to 7.4); p = 0.040). Loss to functional follow-up (53%, n = 109/204) was independently associated with older age (p = 0.001). Patient mortality was the major reason (56.4%, n = 62/110) for loss to follow-up. Older age (p < 0.001) and worse preoperative OKS (p = 0.043) were independently associated with increased mortality risk. An age at time of surgery of ≥ 72 years was 75% sensitive and 74% specific for predicting mortality with an area under the curve of 78.1% (95% CI 70.9 to 85.3; p < 0.001).ConclusionThe Triathlon TKA was associated with clinically meaningful greater improvement in knee-specific outcome when compared to the Kinemax TKA. Loss to follow-up at 12 years was a limitation, and studies planning longer-term functional assessment could limit their cohort to patients aged under 72 years.Cite this article: Bone Jt Open 2024;5(10):911–919.
Using macrobenthic community structure and biotic indices to assess the ecological status of Wulan Estuary, Demak, Indonesia
Authors: HARTATI RETNO , WIDIANINGSIH WIDIANINGSIH , ZAINURI MUHAMMAD , WARDIATNO YUSLI 
Published: October 2024

Abstract. Hartati R, Widianingsih W, Zainuri M, Wardianto Y. 2024. Using macrobenthic community structure and biotic indices to assess the ecological status of Wulan Estuary, Demak, Indonesia. Biodiversitas 25: 3073-3087. Estuaries provide critical habitats for species, and they are valued commercially, recreationally, and culturally. They also filter for sediments and pollutants from rivers before entering the ocean, providing cleaner waters for marine biota. This study presents a unique approach to assessing the ecological status of an estuary using microbenthic community structure and biotic indices with a case study of Wulan Estuary, Demak District, Central Java Province, Indonesia. AZTI’s Marine Biotic Index (AMBI) community structure and biotic indices were used to assess ecological quality at eleven stations and determine the marine macrobenthic fauna's sensitivity to disturbances in two periods, i.e. August 2021 and 2022. A distinct spatial and temporal variation was evident in the macrobenthic community structure, where higher species richness and density were observed in 2022, with some species being more dominant in 2022. The trophic structure analysis showed the dominance of deposit-feeding bivalves in the fine sediments during those sampling intervals. These trophic groups, however, were dispersed less uniformly in the sandy substratum. Compared to the previous year, the density of herbivorous grazers and suspension feeders was higher in 2022. It is also shown by AMBI values that Wulan Estuary belonged to the good (slightly disturbed) to the high (undisturbed) condition, along with other biotic indices, which showed an enhanced habitat quality for benthic organisms. This result revealed the comparative ecological quality of related estuary ecosystems in Indonesia.
Heavy metals concentration in sediment and their bioaccumulation in several organisms in Benoa Bay and Lembongan Island, Bali, Indonesia
Authors: PUTRI PUTU YUDI ADITYA , RASTINA RASTINA , PRARTONO TRI , ISMET MEUTIA SAMIRA 
Published: October 2024

Abstract. Putri PYA, Rastina, Prartono T, Ismet MS. 2024. Heavy metals concentration in sediment and their bioaccumulation in several organisms in Benoa Bay and Lembongan Island, Bali, Indonesia. Biodiversitas 25: 3230-3238. Human activities could be responsible for introducing heavy metals into coastal areas, and it can contaminate coastal waters such as the tourism area of Benoa Bay and coastal ecosystems of Lembongan Island, Bali, Indonesia. This study aimed to assess the extent of heavy metals on the sediment of those area and their accumulation rate in several marine organisms, including macro-algae (Ulva sp.), seagrass (Thalassia hemprichii), and sea urchin (Diadema sp.). Samples of surface sediments and marine organisms were collected at six stations for both areas and the presence of five heavy metals (Fe, Pb, Cd, Cu, and Cr) was determined using the AAS method. The concentration those metals varied significantly across the six stations. The geo-accumulation index showed that the sediment has been contaminated by Pb and Cd. The ecological risk of heavy metals contamination in Benoa Bay was apparently higher compared to that in Lembongan Island. Marine organisms in Benoa Bay also significantly accumulated heavy metals than those observed in Lembongan Island. Bioconcentration factor (BCF) shows that Cd, Cr, and Pb were the most accumulated heavy metals in marine organisms (BCF>1). It, therefore, suggest that future studies of the bioavailability of heavy metals and exploration the varying capacities of marine organisms are required. Such important information can be used to predict the accumulation of heavy metals in human bodies, and the possibly daily consumption of marine organisms caught from Benoa Bay and Lembongan Island waters.
A Proposal of an Isothermal q-EoS for Solids at High Pressures
Authors: Alves Álvaro Santos , A. Farias Franz , Neves dos Santos Rodrigo 
Published: October 2024

We present a new approach to the isothermal equation of state for solids when subjected to high pressures. The central point lies in the fact that the solid subjected to high pressures presents non-linear elastic behavior. We show how the connection between the q-deformed finite deformation theory and the mathematical formalism of Non-Extensive Statistical Mechanics, as postulated by Tsallis [1], allows us to achieve a q-deformed equation of state. We also establish the associated q-deformed interatomic potential and discuss its relation to the Grüneisen parameter.
Corneal nerve loss in adolescents with obesity and acanthosis nigricans
Authors: Gad Hoda , Dauleh Hajar , Chirayath Shiga , Amin Rasha , Pasha Maheen , Elgassim Einas , Haris Basma , Mohamadsalih Ghassan , Jolkka Sari , Biglang-awa Roshirl , Cuatrona Erlinda , Inso Gina , Razon Gerald , Hendaus Mohamed A. , Wahbeh Farah , Sajjadi Fatima , Al-Hashimi Yasmeen , AlNassr Noor , Petropoulos Ioannis N. , Ponirakis Georgios , Hussain Khalid , Malik Rayaz A. 
Published: October 2024

Background/Aim
Obesity and related metabolic abnormalities in adults are associated with peripheral neuropathy. Acanthosis nigricans (AN) is associated with insulin resistance, fatty liver, hyperlipidemia and glucose intolerance, all of which are risk factors for neuropathy. The aim of this study was to investigate if obese adolescents with AN have evidence of small nerve fiber damage.

Material and methods
Adolescents with obesity with and without AN underwent body composition analysis, assessment of vibration perception threshold (VPT), monofilament sensitivity and corneal confocal microscopy (CCM) to quantify corneal nerve fiber density (CNFD), branch density (CNBD), length (CNFL) and inferior whorl length (IWL).

Results
Forty-six participants with obesity with (n = 31) and without (n = 15) AN aged 15(14–17) years were compared to 20 healthy controls aged 13(12–14) years. There was no difference in VPT, monofilament sensitivity and CCM measures between adolescents with obesity and controls. However, adolescents with AN had a significantly higher weight (P = 0.022), fat% (P = 0.029) and fat-muscle ratio (P = 0.012) with a lower CNFD (P = 0.045) compared to those with obesity without AN.

Conclusion
Adolescents with obesity and acanthosis nigricans have a higher fat mass and small nerve fibre loss, indicative of a sub-clinical neuropathy.
O projeto de Martin Heidegger em “Ser e Tempo”: objetivos e método
Authors: Pereira Leão João Victor 
Published: October 2024

Resumo: Este artigo analisa o projeto apresentado por Martin Heidegger em Ser e Tempo de recolocação da pergunta pelo ser. Ali são estabelecidas duas tarefas prévias: a analítica existencial centrada no Dasein (ente humano), e a destruição da história da ontologia com vistas à superação dos preconceitos metafísicos consolidados na tradição filosófica. Analisar-se-á a justificativa dada por Heidegger para que a reformulação da pergunta pelo sentido do ser em geral comece pela ontologia fundamental do Dasein, bem como os argumentos que indicam a necessidade de destruição da metafísica. Analisaremos também o método proposto por Heidegger para a realização desse projeto, a fenomenologia hermenêutica, e como ela se desdobra em seu fazer prático na análise do ente humano.
Palavras-chave: Analítica Existencial; Destruição da Metafísica; Fenomenologia Hermenêutica
El proyecto de Martin Heidegger en "Ser y Tiempo: objetivos y método"
Resumen: Este artículo analiza el proyecto presentado por Martin Heidegger en Ser y Tiempo para replantear la pregunta fundamental sobre el ser. Se establecen dos tareas previas: la analítica existencial centrada en el Dasein (ente humano) y la destrucción de la historia de la ontología con el objetivo de superar los prejuicios metafísicos arraigados en la tradición filosófica. Se examinará la justificación dada por Heidegger para que la reformulación de la pregunta sobre el ser comience con la ontología fundamental del Dasein, así como los argumentos que señalan la necesidad de la destrucción de la metafísica. También se analizará el método propuesto por Heidegger para llevar a cabo este proyecto, la fenomenología hermenéutica, y cómo se despliega en su aplicación práctica en el análisis del ente humano.
Keywords: Análisis Existencial; Destrucción de la Metafísica; Fenomenología Hermenéutica

Data de registro: 15/01/2024
Data de aceite: 09/07/2024
“Our Goal is – Forward and Not to Retreat…” – Uprisings in the Small Ghettos Located in the Territories of Eastern Poland/Western Belarus and Ukraine – A Re-evaluation
Authors: Gershovich Leonid 
Published: October 2024

Abstract
The article analyses the phenomena of the revolts in small ghettos located primarely in the territories of current Belarus and Ukraine that used to be part of Poland during the interwar period. It suggests that one of the reasons for this phenomena was combined influence of life both in the interwar Poland and under the Soviet rule since september 1939 (untill the German-Nazi occupation in june-july 1941).
Relationship between indoor environmental quality and guests’ comfort and satisfaction at green hotels: A comprehensive review
Authors: Abdulaali Hayder Saadoon , Usman Ismar M. S. , Alqawzai Shagea 
Published: October 2024

Abstract
Recent studies have focused on different aspects of green management, practices, and green consumption in the hotel industry. However, there is a need to explore and better understand the association between indoor environmental quality (IEQ) and green hotel guest’s comfort. Therefore, it is essential to explore the effects of IEQ on the comfort and satisfaction of green hotel guests. This study conducts a comprehensive review of the effects of various IEQ parameters, including indoor air quality, thermal comfort, lighting, visual/view, acoustic comfort, building characteristics, decoration, and indoor greenery, on guest’s comfort and satisfaction in green hotels. Based on previous literature, it was also revealed that most current green building schemes lack of comprehensive evaluation of the performance of IEQ dimensions in green hotels. It was also observed that these IEQ parameters show a significant influence on the hotel guest’s comfort and satisfaction. Based on the findings of the literature review, a conceptual model was developed to represent the relationship between the IEQ parameters and guest’s comfort and satisfaction. The proposed conceptual model can be implemented by the hotel management for a comprehensive assessment of guests’ perceptions toward the IEQ in green hotels. The novelty of this study is based on its findings that establish a more effective IEQ evaluation method and serve as the reference scenario of IEQ, which can be a useful tool for both academician and practitioners and contribute to improving the indoor environmental performance of green hotels through highlighting the key IEQ parameters, which affect the comfort and satisfaction of hotel guests.