bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Glibenclamide on the Functional Activity of КATP Channels of Cerebral Arteries in Rats with Streptozotocin Diabetes Mellitus
Authors: Sokolova I. B. , Lobov G. I. 
Published: September 2024

BACKGROUND: In the treatment of diabetes mellitus (DM) for a persistent reduction in blood glucose levels it was widely used glibenclamide — a KATP channels blocker. However, its effects on cerebral circulation have been studied very little. A decrease in the functional activity of KATP channels due to their blocking by glibenclamide against the background of developed endothelial dysfunction may lead to impaired cerebral circulation (especially at the microcirculatory level) and promote remodeling of the vascular network.AIM: To evaluate the effect of glibenclamide on the reactivity of cerebral arteries in rats with streptozotocin-induced diabetes mellitus (STZ-T2DM).TASKS: 1. To study changes in the functional state of KATP channels of pial arteries in STZ-T2DM. 2. To evaluate the effect of glibenclamide on the participation of KATP channels in the formation of basal tone and endothelium-dependent dilatation of pial arteries.MATERIALS AND METHODS: The study was performed on 54 male Sprague Dawley rats. Streptozotocin-induced diabetes mellitus (STZ-T2DM) was modeled by keeping animals on a high-fat diet and administering streptozocin (35 mg/kg). Using an installation for intravital study of pial vessels reactivity, 3 months from the beginning of the experiment, the diameter of the arteries was measured when the brain surface was irrigated with Krebs-Henseleit solution, acetylcholine, glibenclamide, pinacidil and acetylcholine against the background of the action of glibenclamide or pinacidil.RESULTS: With modeling STZ-T2DM, rats developed glucose tolerance and insulin resistance. Compared to control animals, body weight was 1,3 times higher, the percentage of visceral fat was 3 times higher, and the blood glucose level was 3,2 times higher. It was shown that in STZ-T2DM the number of pial artery constrictions under the action of glibenclamide decreased by 1,3 — 1,9 times compared to intact rats. Glibenclamide did not block endothelium-dependent dilation.CONCLUSION: In rats with streptozotocin diabetes, KATP channels take part in the formation of the basal tone of the pial arteries, but the contribution of these channels is reduced on average by 1.5 times compared to healthy rats.The use of glibenclamide in STZ-T2DM does not affect endothelium-dependent dilatation of cerebral arteries.
Erratum: Insufficiency/deficiency of vitamin B12 in patients in the endocrinological practice (Diabetes mellitus. 2024;27(3). doi: 10.14341/DM13181)
Authors: Mokrysheva N. G. , Shestakova M. V. , Ametov A. S. , Antsiferov M. B. , Bakulin I. G. , Vavilova T. V. , Galstyan G. R. , Demidova T. Y. , Dzgoeva F. K. , Karonova T. L. , Lukina E. А. , Mkrtumyan A. M. , Petunina N. А. , Ponomaryov R. V. , Suponeva N. A. , Sukhareva O. Y. , Shamkhalova M. S. 
Published: September 2024

An erratum on « Insufficiency/deficiency of vitamin B12 in patients in the endocrinological practice» by Natalya G. Mokrysheva, Marina V. Shestakova, Alexander S. Ametov, Mikhail B. Antsiferov, Igor G. Bakulin, Tatiana V. Vavilova, Gagik R. Galstyan, Tatiana Y. Demidova, Fatima K. Dzgoeva, Tatiana L. Karonova, Elena A. Lukina, Ashot M. Mkrtumyan, Rodion V. Ponomaryov, Natalia A. Suponeva, Olga Y. Sukhareva, Minara S. Shamkhalova (2024). Diabetes mellitus. 27(3). doi: 10.14341/DM13181An error was made in the list of authors: Nina A. Petunina was not indicated as author of this article. The correct list of authors: Natalya G. Mokrysheva, Marina V. Shestakova, Alexander S. Ametov, Mikhail B. Antsiferov, Igor G. Bakulin, Tatiana V. Vavilova, Gagik R. Galstyan, Tatiana Y. Demidova, Fatima K. Dzgoeva, Tatiana L. Karonova, Elena A. Lukina, Ashot M. Mkrtumyan, Nina A. Petunina, Rodion V. Ponomaryov, Natalia A. Suponeva, Olga Y. Sukhareva, Minara S. Shamkhalova.The identifier in the ORCID system for F.K. Dzgoeva was also indicated incorrectly. The correct link is: https://orcid.org/0000-0002-0533-7652.The editorial board apologize for this error and state that this does not change the scientific conclusions of the article in any way.The original article has been updated.
Representations of the Holocaust in the Jewish Museum in Kaliningrad
Authors: Leiserowitz Ruth 
Published: September 2024

Abstract
In November 2018, the reconstructed synagogue was inaugurated in Kaliningrad (Russian Federation) on the site of the house of worship destroyed on the night of the pogrom of 1938, Kristallnacht. Since 2022, a small Jewish Museum has also opened in the active synagogue, the centerpiece of which is a thematically conceptualized permanent exhibition. In the following article, the initial situation, mission, and thematic expectations for the creation of the permanent exhibition are described. It was desired that it should have an identity-forming and identity-promoting effect on the Jews of the Kaliningrad congregation and the entire region. Furthermore, it should be educational and entertaining for the population and tourists of the area, but also represent a place of remembrance of the former Jewish life and the Holocaust for the Jewish visitors of the region. Subsequently, the chosen exhibition media are described, as well as the selection of narratives and their respective media implementation. The text also sheds light on the object from the perspective of Jewish cultural heritage: The Kaliningrad region is one of the Eastern European post-displacement areas in which German traces (including German-Jewish traces) are regarded as a dissonant heritage. The authorized heritage discourse does not accept the consequences of the Holocaust here and ignores the city’s Jewish heritage. How can Jewish cultural heritage be made visible under these conditions? How can the new museum contribute to a change?
The Derivation of the Categories of Quantity
Authors: Haeck Levi 
Published: September 2024

Abstract
In this paper, I propose to resolve the controversy over the derivation of the categories of quantity by spelling out three claims: (1) the three quantitative functions/forms of judgment (universal-particular-singular), qua synthetic categories of quantity (unity-plurality-totality), lawfully direct the determination of sensible manifolds as singular totalities, which (2) brings to light a specifically categorial type of judgmental activity, distinguishable from but presupposed by empirical judgments. This calls for (3) pairing the category of totality with the singular judgment and the category of unity with the universal judgment (‘Order B’), rather than pairing the singular judgment with unity and the universal judgment with totality (‘Order A’). At stake in this controversy is our understanding of the categories’ normativity, their scope, and the division of labor between intuitions and categories in individuating objects.
Crystal structure of 1,1′,1″-(nitrilotris(ethane-2,1-diyl))tris(3-(4-(((E)-pyridin-2-ylmethylene)amino)phenyl)urea), C45H47N13O4
Authors: Li Jie , Dong Yinghan , Qiu Mengying , Han Haiwei , Pei Xiaoyan 
Published: September 2024

Abstract
C45H47N13O4, triclinic, P1̄ (no. 2), a = 10.242(6) Å, b = 14.766(15) Å, c = 15.503(8) Å, α = 70.91(2)°, β = 88.052(16)°, γ = 74.13(3)°, V = 2127(3) Å3, Z = 2, R

gt
(F) = 0.0411, wR

ref
(F
2) = 0.1059, T = 120(2) K.
The crystal structure of N-benzylquinoline-2-carbothioamide, C17H14N2S
Authors: Zhu Xiaoming , Ou Jiaqi , Luo Na , Deng Yuxuan , Nie Yuming , Xiang Jiafeng , Fang Shixin 
Published: September 2024

Abstract
C17H14N2S, Orthorhombic, P212121 (no. 19), a = 5.9687(10) Å, b = 8.4626(14) Å, c = 28.786(5) Å, V = 1454.0(4) Å3, Z = 4, R
gt(F) = 0.0315, wR
ref(F
2) = 0.0824, T = 296(2) K.
Neurobiological mechanisms in the kynurenine pathway and major depressive disorder
Authors: Bertollo Amanda Gollo , Mingoti Maiqueli Eduarda Dama , Ignácio Zuleide Maria 
Published: September 2024

Abstract
Major depressive disorder (MDD) is a prevalent psychiatric disorder that has damage to people’s quality of life. Tryptophan is the precursor to serotonin, a critical neurotransmitter in mood modulation. In mammals, most free tryptophan is degraded by the kynurenine pathway (KP), resulting in a range of metabolites involved in inflammation, immune response, and neurotransmission. The imbalance between quinolinic acid (QA), a toxic metabolite, and kynurenic acid (KynA), a protective metabolite, is a relevant phenomenon involved in the pathophysiology of MDD. Proinflammatory cytokines increase the activity of the enzyme indoleamine 2,3-dioxygenase (IDO), leading to the degradation of tryptophan in the KP and an increase in the release of QA. IDO activates proinflammatory genes, potentiating neuroinflammation and deregulating other physiological mechanisms related to chronic stress and MDD. This review highlights the physiological mechanisms involved with stress and MDD, which are underlying an imbalance of the KP and discuss potential therapeutic targets.
The Potential of Deleterious rhizobacteria to Control Primary Weed <i>Echinochloa </i>sp. on Rice
Authors: Hoesain Mohammad , Masnilah Rachmi , Nurchayanti Suhartiningsih Dwi , Pradana Ankardiansyah Pandu , Alfarisy Fariz Kustiawan , Sari Dwi Tirta , Ramadhan Farchan Mushal Al , Rismayani  , Tarigan Sri Ita 
Published: September 2024

Deleterious rhizobacteria (DRB) is one of the rhizobacteria that can be used as a bioherbicide and can stimulate plant growth. The objectives that can be obtained from this study are to determine the potential of DRB on the growth of weeds Echinochloa crusgalli and Echinochloa colona on rice. Variables observed in this study were identification of secondary metabolites, measurement of weed sprouts, percentage effectiveness of bacterial isolates against weed seeds, normal sprouts, abnormal sprouts, fresh seeds that did not grow and dead seeds. The aim of this study is to explore biological agents that can be used to control the main weeds of rice crops. This candidate could be a recommendation for environmentally friendly controls. Exploration of the DRB group was obtained by collecting soil samples around the roots of rice crops. Then isolate it, identify as morphologically and physiologically, and test it in vitro studies. The results showed that DRB had the potential to control weed growth and could stimulate the growth of rice. The application of PFA and PFB isolates had a significant effect on inhibiting the length of weed roots and buds, the average percentage of control effectiveness > 80-90%. Novelty in this study could be found as candidate groups of DRB bacteria with specific locations to control the weed Echinochloa sp. on rice crops. For society, this research could be an alternative to reduce dependence on synthetic herbicides . DRB has the potential to be formulated into a bioherbicide to control weeds.
"Sending baby dust to you all..."
Authors: Butcher Sally 
Published: September 2024

My ongoing interdisciplinary practice-based PhD research considers ways in which understandings of (In)fertility are manifested within the texts of women in personally led online forum spaces and the bigger hidden narratives around these fragments. Looking at (dis)embodiment through language within artistic practice, it considers alternative linguistic interpretations of this dis-ease within and against authoritative medicalised rhetoric and asks what other semantics can emerge in dialogue here. This seeks to reimagine(In)fertile Embodiment through creative feminist praxis, within non-normative “sub-maternal” subjectivities and temporalities, traversing intersections of invisibility and silence through formulations of absence and its material presence. Emerging experiments, as discussed in this article, embrace an embodied methodology of hope and failure, interspersing words and images, text and matter, through interpretations of textual metaphor and data visualisation. The research seeks to engage audiences emotionally around this stigmatised reproductive discourse and assert its re-presentation within a new “maternal spectrum”, expanding the parameters of maternal art and beyond.
INFLUENCE OF DIESEL FUEL COMPOSITION ON COLD FLOW IMPROVER EFFECTIVENESS
Authors: Khamadalieva Gulnaz M. , Baulin Oleg A. , Gilmutdinov Amir T. , Khabarova Ksenia I. , Ayupova Azaliya A. 
Published: September 2024

In recent years there has been an increase in the requirements for the diesel fuel quality in our country. One of the most important indicators of diesel fuel quality is its low-temperature properties. To improve the low-temperature characteristics of diesel fuel it is recommended to add cold flow improvers. These additives help to lower the pour point, increase the cold filter plugging point and extend the range of winter fuels. However, there is a challenge in using these additives as their effectiveness can vary depending on the composition of the fuel. Fuels with a wide boiling range 90 %–20 % distillation curve of 100 °C or more and an end boiling point of more than 25 °C are usually more susceptible to cold flow improvers.The article examines the effect of various fuels with different fractional and hydrocarbon compositions produced at Gazprom Neftekhim Salavat LLC on the performance of a cold flow improver based on petrochemical industry by-products developed at Ufa State Petroleum Technological University. It was found that the highest efficiency of the additive at its maximum concentration (0.2 % by weight) was observed on a sample of diesel fuel with the lowest content of paraffin hydrocarbons (52.7 % by weight). The optimal boiling range for this sample was 90 %–20 % – 110 °C, the «end of boiling – 90 %» – 25 °C. The depressor effect of the additive on other diesel fuel samples was found to be negligible indicating its poor compatibility with fuels of the studied composition. Therefore, in the production of diesel fuel it is important to have a variety of cold flow improvers that can be tailored to suit fuels with different fractional and hydrocarbon compositions.
Desde el prisma del pianista: preparación e interpretación de la Sonata para violín y piano, Kv. 304, de W. A. Mozart
Authors: Algarra Ulierte Alejandro 
Published: September 2024

The aim of this research is to highlight the role played by the piano along with other instruments in the chamber music genre, through the interpretative study and analysis of Wolfgang Amadeus Mozart's Sonata Kv. 304 (1778). In this regard, the pianist's point of view will be fundamental to know how to approach a chamber music score, with autonomy and knowledge of the composer's intention and of the way the keyboard instrument must be treated. Establishing the creative phases of the performer's work depends on factors such as the musician's own training, the stylistic approach and the personal touch given to the piece. The different types of difficulties and composer-specific writing elements will have to be taken into account with a different technical and interpretative approach.
El Dibujo autorretrato y autorrefencialidad
Authors: Carrillo Cabezas Sofía , Alor Calero Isabel María 
Published: September 2024

Art is not born from art alone, knowledge of things is, in most cases, the starting point of a more eloquent artistic practice. The content of a work always comes from the approach and how it is shown. Oral language is the first step to specify what you want to show with plastic language.
Art does not arise just from art, knowledge of things is in most of the cases the starting point for a more eloquent artistic practice. The content of a work always comes from the approach and how it is presented. Spoken language is the first step in specify what one wants to convey through visual language.
The spontaneity of painting something they have seen before, their portrait, ensures that the idea of it exists only in their mind. Therefore, the outcome will stem from knowledge but without the ability to consult photographs of themselves. Artistic precedents will help to initiate the reflection that will start from reality and from the understanding of different realities within the LGBTQ+ community.
Yoga for Veterans with PTSD: Intervention Feasibility, Changes in PTSD Symptom Severity, and Psychological and Physiological Health-Related Fitness Outcomes
Authors: Bollaert Rachel E. , Bennett Meghan M. , Davis Kaley E. , Hillard Cecilia J. , Whittle Jeffrey , Franco Zeno , Broadwell Shayne , Fitzgerald Jacklynn 
Published: September 2024

Abstract
Posttraumatic stress disorder (PTSD) is a burdensome disorder associated with lower quality of life and increased morbidity and mortality. Veterans are particularly at risk for PTSD resulting from experiencing traumatic events during military service. Current treatments for PTSD often fail to remediate symptoms and are associated with high dropout rates; therefore, complementary and integrative health approaches, such as yoga, are being considered to treat PTSD-related symptoms. The present study investigated the feasibility of a 12-week, 1-hour/week, in-person, trauma-informed mindful resilience yoga intervention for improving PTSD symptom severity and secondary psychological outcomes (e.g., physical and mental health, sleep, mindfulness, and self-efficacy), physiological health-related fitness outcomes (e.g., body composition and muscular strength), and physical activity outcomes (e.g., accelerometry) in a sample of veterans with PTSD. Results demonstrated the intervention to be feasible, with 12 participants (9 male, 3 female; mean age 50.3) completing the program (10 participants completed ≥ 75% of the 12 sessions). Statistically significant improvement was demonstrated in the “nonjudging of inner experience” aspect of mindfulness (p = 0.005, d = 1.280). Although not considered statistically significant (p &gt; 0.008), the majority of outcomes demonstrated trending improvement from pre- to postintervention, with small to large Cohen's d effect sizes. The novelty of this study is represented by the trending improvements in physiological health-related fitness outcomes, with lean mass and handgrip strength demonstrating small effect sizes (d = 0.243 and d = 0.267, respectively). Our results extend the existing literature on the feasibility and potential effectiveness of yoga as a complementary or integrative therapy for PTSD in the veteran population.
Efficacy of dentin bio-modification with quercetin-bromelain on shear bond strength of teeth restored with MICR technique
Authors: B R Prashanth , Rudrapada Priyanka , Mishra Binith Kumar , Karale Rupali , N S Shivaranjan , MG Mangala 
Published: September 2024

: Dentin biomodification with natural extracts is done to improvise the bond strength with chemomechanical caries removal techniqueTo evaluate and compare the efficacy of dentin bio-modification with quercetin-bromelain on SBS of teeth restored with Minimal Invasive Caries Removal (MICR) technique 48 extracted teeth with class I dentinal caries were divided into 2 followed by subdivided into 2 subgroups in each group (n=12).Group1: Without dentin biomodificationCaries removal done with No.4 round bur (1a) & V-carie-solve (1b)Group2: With dentin biomodification (Quercetin-Bromelain)Caries removal done with No.4 round bur (2a) & V-carie-solve (2b) followed by dentin biomodificationAfter composite restoration, samples were subjected to immediate SBS analysis. Two samples were examined under SEM from each subgroup.: Kruskal Wallis test with Bonferroni’s correction for multiple tests was used to assess the mean difference between the groups.: Dentin biomodification with mechanical and MICR technique showed better bond strength. Dentin biomodification with mechanical caries removal showed highest SBS. : Dentin bio-modification with Quercetin-Bromelain could improve bond strength with MICR technique.
Management of external invasive resorption: A case report
Authors: Jose Aleena , Babu Anulekh , V G Sam Joseph , S L Satheesh , M Rasha Usman 
Published: September 2024

Invasive cervical resorption (ICR) is a particularly aggressive form of external tooth resorption that originates in the cervical region of the involved tooth. The primary treatment objective is to completely remove all the resorbing tissues and restoration of the resorptive defect using an appropriate filling material to achieve functional and aesthetic demands. Managing defects that extend both towards the crown and root can be particularly challenging.This case report describes the management of a case of Class 3 (Heithersay classification) and 2Bp (Patel 3D classification) ICR in the maxillary right central incisor. The approach involved a surgical procedure to remove the affected tissue followed by restoration of the defect using a tri-layered combination of Biodentine, resin-modified glass ionomer cement and composite resin.Dr Aleena Jose, Dr Anulekh Babu, Dr Sam Joseph V G, Dr Satheesh S L, Dr Rasha Usman M
Unveiling radix entomolaris: A case report and literature review on mandibular first molar anatomical variation
Authors: Singh Avishek , Suri Shally , Jain Rajnish K , Khetarpal Ambica , Bhardwaj Nikhil , Arora Rachita 
Published: September 2024

The mandibular first molar is renowned for its typical root anatomy, characterized by a mesial and distal root. Nonetheless, anatomical variations may exist, demanding a meticulous approach during endodontic procedures. The presence of an extra lingual root distally, termed radix entomolaris (RE), poses challenges to successful root canal treatment. Accurate interpretation of radiographs and precise angulations are crucial for identifying the pulp chamber and root anatomy.This study aims to present a compelling case of a mandibular first molar with an additional distolingual root (RE) and to conduct a thorough survey of existing literature to determine the incidence of this anatomical feature. The objective is to emphasize the significance of recognizing and understanding this unusual root and its canal morphology in ensuring the efficacy of root canal treatment.The failure to identify radix entomolaris (RE) can significantly impact the prognosis of endodontic treatment. Awareness and comprehension of this anatomical variation contribute to the successful outcome of root canal procedures in mandibular first molars. Proper identification, treatment planning, and meticulous execution are imperative when faced with such variations.
Concepções docentes sobre o processo avaliativo de alunos do Atendimento Educacional Especializado
Authors: Cunha Suênia Roberta Ferreira de Carvalho , Massaro Munique 
Published: September 2024

As concepções docentes podem influenciar diretamente a atuação no processo de avaliação dos alunos, principalmente àqueles público-alvo da Educação Especial. Assim, o objetivo da pesquisa foi analisar as concepções de professoras do Atendimento Educacional Especializado e do ensino comum no processo avaliativo de alunos público-alvo da Educação Especial no modelo de ensino remoto. Foi realizado um Estudo de Caso em uma escola pública municipal com duas professoras. Os dados foram coletados por meio de observações nos grupos de WhatsApp, mensagens, ligações telefônicas e entrevistas. Todos os contatos geraram registros no diário de bordo. Já as mensagens escritas, os áudios trocados pelo WhatsApp e as entrevistas foram transcritas de forma fidedigna. Para a realização da análise dos dados, utilizou-se a técnica de triangulação e a Análise de Conteúdo. Os resultados demonstraram que as concepções das professoras acerca dos alunos público-alvo da Educação Especial são restritas e limitadas por um viés médico e as concepções acerca da avaliação são baseadas por uma avaliação classificatória, pautada na mensuração da aprendizagem. Ressalta-se que se faz necessário fomentar a reflexão acerca das concepções dos professores para promover efetivamente a educação inclusiva.