bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time pressure, coping strategies and work engagement: moderation of inclusive-leadership
Authors: Mangi Tanveer Ahmed , Sun Wei , Khoso Wali Muhammad , Ambreen Shehla 
Published: October 2024

PurposeThis study aims to unravel the effects of time pressure on work engagement within Chinese organizational settings, considering the moderating effect of inclusive leadership and the mediating role of coping strategies. It seeks to apply and extend theories such as the job demands-resources (JD-R) model, Lazarus’s stress and coping (LSC) framework and leader–member exchange (LMX) theory on stress and coping to understand these dynamics comprehensively.Design/methodology/approachThe study collected responses from 211 Chinese professionals in the manufacturing sector through a structured questionnaire. Multiple regression analysis was used to test the hypotheses.FindingsResults reveal that problem-focused coping strategies positively correlate with work engagement, whereas emotion-focused coping strategies do not show a significant association. Both emotion-focused and problem-focused coping strategies mediate the relationship between time pressure and work engagement. Additionally, inclusive leadership positively moderates the relationship between time pressure and both problem-focused and emotion-focused coping strategies.Practical implicationsOrganizational leaders and HR practitioners of companies can devise interventions to enhance employee engagement by leveraging the findings of this study, which advances our understanding of the critical role of coping strategies and the influence of inclusive leadership, particularly under time pressure, which is prevalent in fast-paced work environments.Originality/valueThe research integrates the JD-R model, LMX theory and LSC framework to explore workplace dynamics in China, presenting new insights into coping mechanisms and leadership roles in high-pressure environments.
Gamification and customer brand engagement: a review and future research agendas
Authors: Malik Garima , Pradhan Debasis , Rup Bikash Kumar 
Published: October 2024

PurposeExtant literature shows that gamification is an effective tool for enhancing customer brand engagement. However, there is a need for a structured review of the literature on how and to what extent gamification fosters customer brand engagement. This hybrid literature review synthesizes extant research on gamification and its impact on customer brand engagement.Design/methodology/approachThe study is based on 45 articles drawn from 33 journals from the Scopus database. This article conducts a systematic review of theory, context, characteristics and methods employed in extant research, identifies contemporary themes and presents future research avenues. It also conducts a bibliometric analysis to identify the most prominent journals, authors, articles and themes.FindingsThis review identifies various patterns and trends of psychological capital research, and it unfolds four major themes – gamification and customer engagement, gamification and e-marketing, gamification and sustainable marketing and gamification and customer experience.Practical implicationsThis review offers key insights into managerial implications.Originality/valueIt is one of the first endeavors to conduct a structured review of research related to gamification and customer engagement. It presents a conceptual framework that shows the relationships between gamification and customer engagement. This systematic review offers several future research agendas to spur scholarly research and presents key insights into the process of gamification in marketing to enhance customer brand engagement.
Green nexus womenpreneurs: harnessing internal-external capabilities for sustainable MSMEs fashion
Authors: Alfarizi Muhammad , Ngatindriatun Ngatindriatun , Firmansyah Yura Witsqa 
Published: October 2024

Purpose
This study aims to analyze the capabilities and external conditions of womenpreneur owners of micro, small and medium enterprises (MSMEs) Fashion EcoPrint Indonesia in green business practices and their implications for sustainable business performance.

Design/methodology/approach
This study chooses a quantitative approach with a sustainable business internal-external capability model. Using the structural equation modeling-partial least square analysis tool, the analysis was conducted on a sample of womenpreneurs who owned MSMEs EcoPrint Indonesia (n = 493).

Findings
In the internal capability dimension, total quality environment and green core competence affect green supply chain management, affecting green product innovation performance. Meanwhile, women entrepreneurs’ external capability dimensions (regulation, customer awareness of the environment and technological innovation infrastructure) are connected to sustainable development business capabilities, which affect the performance of green process innovation. The study confirms that green products and processes have the potential to influence sustainable business performance. A key finding is the strong influence of environment-based total quality management governance on both sides. At the same time, womenpreneurs have a significant impact on their respective dimensions.

Research limitations/implications
This study has implications for increasing competency, Sustainable MSME industrial infrastructure, and protecting women in developing countries. The theoretical implications of creating a model that examines the impact of womenpreneurs’ internal and external abilities on eco-friendly businesses’ success are significant for developing nations’ promising growth.

Originality/value
This study explores women’s contributions to family well-being and environment-based economies, focusing on eco-friendly supply chain management and sustainable external capabilities of women entrepreneurs in Indonesia, using a gender equality approach in developing economies.
Investigating patient satisfaction with a hand therapy telehealth service during COVID‐19
Authors: Graham Elise M. , Ahern Elspeth 
Published: October 2024

AbstractIntroductionThroughout the COVID‐19 pandemic, outpatient hand therapy services were restricted. The use of telehealth was adopted to continue to provide care to patients with hand injuries.This survey aims to investigate patient satisfaction with hand therapy delivered via telehealth in a NSW public tertiary referral metropolitan setting and explore whether this differs for specific hand injury/conditions and treatments offered.MethodsPatients using hand therapy services via telehealth between 28 June 2021 and 27 May 2022 responded to a bespoke electronic survey. Participants were grouped depending on their particular injury/condition and treatment received. Analysis was conducted using MS Excel, and correlations were determined by using Fisher's exact test.Community and consumer involvementNo consumers were involved in the study design or analysis.ResultsSixty‐eight of 262 patients responded to the survey (26% response rate). Overall results showed high patient satisfaction (n = 55, 81%) with hand therapy delivered via telehealth with most patients agreeing that telehealth should be offered going forward (n = 59, 87%). Benefits reported by patients included convenience, reduced travel time and parking issues, and time saving. Patients receiving therapy for ‘finger thumb bony injury with K wires’ demonstrated a statistically significant association of lower satisfaction with telehealth (n = 3, 43%, P = 0.02). Patients receiving wound care over telehealth were just as satisfied with their experience (n = 15, 82%) as overall results (n = 55, 81%).ConclusionThe survey suggests that patients are satisfied with their experience of telehealth for hand therapy. Patients with finger thumb bony injuries with k wires may be less suitable for telehealth. Wound care appears to be well received over telehealth in a hand therapy population.PLAIN LANGUAGE SUMMARYThere is little evidence to guide hand therapists in which conditions or injuries patients find can be managed well with telehealth. Patients who answered a survey about their experience with telehealth for their hand therapy management overall reported satisfaction with the experience. Some patients had undergone surgery for broken fingers and thumbs using wires to hold the bone together while it healed. These patients were less likely to find telehealth satisfactory for their hand therapy care. Most patients requiring wound care over telehealth found this satisfactory.
Understanding the ‘imposters’
Authors: Dyson Caroline 
Published: October 2024

AbstractAs teachers, we think that we understand the challenges of educating children and adults when addressing multiculturalism, immigration and racism. But are we getting it right if we do not know the experiences and challenges faced by international students or even know the perspectives of typically white British students learning in an increasingly multicultural education system? We have all at some point felt like an imposter, isolated and insecure but this is a very real, everyday experience for many people who happen to come from a different country or have different coloured skin. We need to challenge our perspectives by thinking outside of the protective box and seeking information from varied and contemporary sources who understand these challenges the most. This is a look at how a refugee centre has inspired a new way of teaching adult nursing students, and how utilising the enormous amount of knowledge in such centres can also be used to give valuable insight and a fresh perspective when it comes to teaching young people in schools, where the challenges of stamping out racism can be tackled early and head‐on.
The role of non‐coding RNAs in fibroblast‐like synoviocytes in rheumatoid arthritis
Authors: Zheng Yongquan , Cai Xiaoyu , Ren Fujia , Yao Yao 
Published: October 2024

AbstractRheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by synovial hyperplasia, and fibroblast‐like synoviocytes (FLSs) constitute the majority of cells in the synovial tissue, playing a crucial role in the onset of RA. Dysregulation of FLSs function is a critical strategy in treating joint damage associated with RA. Non‐coding RNAs, a class of RNA molecules that do not encode proteins, participate in the development of various diseases. This article aims to review the progress in the study of long non‐coding RNAs, microRNAs, and circular RNAs in FLSs. Non‐coding RNAs are involved in the pathogenesis of RA, directly or indirectly regulating FLSs' proliferation, migration, invasion, apoptosis, and inflammatory responses. Furthermore, non‐coding RNAs also influence DNA methylation and osteogenic differentiation in FLSs. Therefore, non‐coding RNAs hold promise as biomarkers for diagnosing RA. Targeting non‐coding RNAs in FLSs locally represents a potential strategy for future therapies in RA.
Viability discrimination of bacterial microbiomes in home kitchen dish sponges using propidium monoazide treatment
Authors: Carstens Christina K. , Salazar Joelle K. , Sharma Shreela , Chan Wenyaw , Darkoh Charles 
Published: October 2024

AbstractDish sponges are known to support the proliferation of human bacterial pathogens, yet they are commonly used by consumers. Exposure to foodborne pathogens via sponge use may lead to illness, a serious concern among susceptible populations. The extent of exposure risks from sponge use has been limited by constraints associated with culture‐independent or dependent methods for bacterial community characterization. Therefore, five used dish sponges were characterized to evaluate the presence of viable bacterial foodborne pathogens using the novel application of propidium monoazide (PMA) treatment and targeted 16S rRNA gene amplicon sequencing. Select pathogen viability was confirmed using targeted selective enrichment. The taxonomic abundance profiles of total and viable sponge microbiomes did not vary significantly. The numbers of unique bacterial species (p = 0.0465) and foodborne pathogens (p = 0.0102) identified were significantly lower in viable sponge microbiomes. Twenty unique bacterial foodborne pathogens were detected across total and viable sponge microbiomes, and three to six viable foodborne pathogens were identified in each sponge. Escherichia coli and Staphylococcus aureus were identified in each viable sponge microbiome, and viable E. coli were recovered from two sponges via targeted selective enrichment. These findings suggest that sponge‐associated bacterial communities are primarily viable and contain multiple viable bacterial foodborne pathogens.
Low microbial abundance and community diversity in the egg capsule of the oviparous cloudy catshark (Scyliorhinus torazame) during oviposition
Authors: Takagi Wataru , Masuda Ayami , Shimoyama Koya , Tokunaga Kotaro , Hyodo Susumu , Sato‐Takabe Yuki 
Published: October 2024

AbstractVertebrate embryos are protected from bacterial infection by various maternally derived factors, yet little is known about the defence mechanisms in elasmobranchs. This study aimed to characterize the intracapsular environment of freshly laid eggs of the oviparous catshark (Scyliorhinus torazame) by investigating the microbial abundance and microbiota to understand its potential contribution to embryonic defence. The egg capsule of oviparous elasmobranchs is tightly sealed until pre‐hatching, after which seawater flows into the capsule, exposing the embryos to the surrounding seawater. We found that early embryos were highly vulnerable to environmental pathogens, suggesting that the embryos are somehow protected from infection before pre‐hatching. Indeed, the intracapsular environment of freshly laid eggs exhibited significantly low bacterial density, maintained until pre‐hatching. Furthermore, the microbiome inside eggs just after oviposition differed markedly from those of rearing seawater and adult oviducal gland epithelia; these eggs were predominantly populated by an unidentified genus of Sphingomonadaceae. Overall, this study provides compelling evidence that early embryos of oviparous cloudy catshark are incubated in a clean intracapsular environment that potentially plays a significant role in embryonic development in oviparous elasmobranchs.
Suicide in people prescribed opioid‐agonist therapy in Scotland, United Kingdom, 2011–2020: A national retrospective cohort study
Authors: Fraser Rosalyn , Yeung Alan , Glancy Megan , Hickman Matthew , Jones Hayley E. , Priyadarshi Saket , Horsburgh Kirsten , Hutchinson Sharon J. , McAuley Andrew 
Published: October 2024

AbstractBackground and aimsOpioid dependence is associated with an increased risk of suicide. Drug‐related mortality among people with opioid dependence in Scotland has more than tripled since 2010; less is known about changes in suicide risk. We aimed to determine if opioid agonist therapy (OAT) in Scotland is protective against suicide and to measure trends in suicide rates in those with opioid dependence over time.DesignRetrospective cohort study.SettingScotland, UK.Participants46 453 individuals in Scotland who received at least one prescription for OAT between 2011 and 2020 with over 304 000 person‐years (pys) of follow‐up.MeasurementsWe calculated standardised mortality ratios (SMR) using the age‐ and sex‐specific suicide rates in Scotland for years 2011–2020. We fitted multivariable competing‐risk regression models to estimate suicide rates by OAT exposure and to estimate trends over time, adjusting for potential confounders.FindingsThere were 575 deaths classed as suicide among the cohort and the overall suicide rate was 1.89 (95% confidence interval [CI] = 1.74–2.05) per 1000 pys. Age and sex SMR for suicide was 7.05 times (95% CI = 6.50–7.65) higher than in the general population. After adjustment, OAT was shown to be highly protective against suicide, with rates more than three times greater (adjusted hazard ratio: 3.07; 95% CI = 2.60–3.62) off OAT compared with on OAT. Suicide rates decreased over time, falling from 2.57 (95% CI = 2.19–3.02) per 1000 pys in 2011–12 to 1.48 (95% CI = 1.21–1.82) in 2019–20.ConclusionPeople with opioid dependence in Scotland appear to have a greater risk of suicide than the general population. Treatment is protective, with rates of suicide lower among those on opioid agonist therapy. Suicide rates have decreased over time, during a period in which drug‐related death rates in Scotland have risen to globally high levels.
Preliminary Characterisation of Immune Cell Populations in the Oral Mucosa of a Small Cohort of Healthy Dogs (Canis lupus familiaris)
Authors: Soltero‐Rivera Maria , Bailey Myles , Blandino Andrew , Arzi Boaz , Vapniarsky Natalia 
Published: October 2024

ABSTRACTPre‐determined anatomical locations in the oral cavity were biopsied, and their histomorphology was characterised using haematoxylin and eosin staining (H&E). The most abundant cell type was of dendritic morphology. Lymphocyte foci were not evident in the palatoglossal folds or the gingiva. Immunohistochemical staining (IHC) for validated leukocyte markers followed, including CD3, CD20, CD79α, CD204, and Iba1. Consistent with H&E findings, CD204 immunoreactivity predominated amongst all niches. With the exception of the alveolar mucosa and palatoglossal folds, we also demonstrate a significant difference in the population of macrophages by region for only the Iba1 antigen (p < 0.0001). B lymphocytes were found, and a significant difference was noted in the sub‐epithelium where CD20‐positive cells outnumbered those labelled as CD79a positive (p = 0.001), suggesting the possibility that these cells are in an active state in health. A similar significant difference was found in the subepithelial tissue for myeloid cells, as there were more cells labelled as CD204 positive over Iba1, which, along with their distribution pattern, indicates a possible functional and morphological overlap between these cells. No significant difference was found in epithelial tissues for cells of either myeloid or lymphoid origins. The results from this study suggest different regions of the oral cavity exhibit variations in the distribution of immune cells, particularly macrophages and B lymphocytes. Though more studies would be needed to confirm these findings, these differences may have implications for the immune response and overall health of the oral mucosa.
A machine learning‐based workflow for predicting transplant outcomes in patients with sickle cell disease
Authors: Li Haiou , Sachdev Vandana , Tian Xin , Nguyen My‐Le , Hsieh Matthew , Fitzhugh Courtney , Limerick Emily , Coles Wynona , Asomaning Nancy , Conrey Anna , Wu Colin O. , Thein Swee Lay 
Published: October 2024

SummaryAllogeneic haematopoietic cell transplantation (HCT) with HLA‐matched sibling donor remains the most established curative therapeutic option for patients with sickle cell disease (SCD). However, it is not without risks, highlighting the need for a risk stratification system. Utilizing a machine learning (ML) approach that combines clinical and imaging variables, we identified red cell distribution width and renal organ damage as important risk factors for patients undergoing HCT. This ML‐based algorithm, similar to an approach previously reported for predicting mortality in patients with SCD, should be applicable to risk factor discovery in similar studies.
Conditional survival of younger patients with mantle cell lymphoma: Results from a randomized phase III trial of the European MCL Network
Authors: Jiang Linmiao , Dreyling Martin , Hermine Olivier , Mansmann Ulrich , Walewski Jan , Ribrag Vincent , Thieblemont Catherine , Pott Christiane , Bachy Emmanuel , Feugier Pierre , Hübel Kai , Schumacher Martin , Hoster Eva 
Published: October 2024

SummaryDuring a fatal disease, patients often request updated information on their prognosis. After patients have already survived a certain time, conditional survival captures their future survival probability. We investigated conditional overall and failure‐free survival in 473 younger mantle cell lymphoma (MCL) patients from a randomized phase III trial comparing immunochemotherapies R‐CHOP and alternating R‐CHOP/R‐DHAP before autologous transplantation. Using conditional Kaplan–Meier method and Cox regression, we estimated subsequent survival of patients who had survived 1–8 years, considering MIPI, Ki‐67, and treatment failure status. Starting at a lower level, R‐CHOP patients only showed increasing subsequent survival as they survived longer (5‐year conditional survival: 72% and 81% after surviving 1 and 7 years), while R‐CHOP/R‐DHAP patients had stable future survival over time (77% and 78%). The prognostic value of MIPI diminished after 3 years in R‐CHOP patients but remained unchanged after R‐CHOP/R‐DHAP. Patients with treatment failure had markedly inferior survival compared with those in ongoing remission, regardless of the time survived. The longer patients remained in remission, the longer they would stay free of treatment failures. Our results enable personalized counselling for younger MCL patients by offering dynamic prognosis and underscore the importance of highly effective first‐line treatment to improve survival.
FOXP3+/CD8+ ratio associated with aggressive behavior in RUNX3‐methylated diffuse esophagogastric junction tumor
Authors: Maruyama Suguru , Imamura Yu , Toihata Tasuku , Haraguchi Ikumi , Takamatsu Manabu , Yamashita Makiko , Nakashima Yuichiro , Oki Eiji , Taguchi Kenichi , Yamamoto Manabu , Mine Shinji , Okamura Akihiko , Kanamori Jun , Nunobe Souya , Sano Takeshi , Kitano Shigehisa , Noda Tetsuo , Watanabe Masayuki 
Published: October 2024

AbstractThe tumor immune microenvironment is increasingly becoming a key consideration in developing treatment regimens for aggressive cancers, with evidence that regulatory T cells (Tregs) attenuate the antitumor response by interrupting cytotoxic T cells (CD8+). Here, we hypothesized the prognostic relevance of the proportions of Tregs (marked by forkhead box protein 3 [FOXP3]) and CD8+ cells in diffuse, non‐Epstein–Barr virus (EBV)/non‐microsatellite instability (MSI)‐high gastroesophageal adenocarcinomas (GEAs), which are clinically characterized as more aggressive, immunologically inactive tumors as compared with their intestinal counterparts. Cell‐count ratios of FOXP3+/CD8+ expression were calculated at the intratumoral region and invasive margin discretely on digital images from 303 chemo‐naive non‐EBV/non‐MSI‐high esophagogastric junction (EGJ) adenocarcinomas. A significant modifying prognostic effect of tumor histology was observed between 5‐year EGJ cancer‐specific survival and the FOXP3+/CD8+ ratio at the invasive margin in pStage I–III tumors (p for interaction = 0.022; hazard ratio [HR] = 8.47 and 95% confidence interval [CI], 2.04–35.19 for high ratio [vs. low] for diffuse; HR = 1.57 and 95% CI, 0.88–2.83 for high ratio [vs. low] for intestinal). A high FOXP3+/CD8+ ratio at the invasive margin was associated with RUNX3 methylation (p = 0.035) and poor prognosis in RUNX3‐methylated diffuse histological subtype (5‐year EGJ cancer‐specific survival, 52.3% for high and 100% for low, p = 0.015). Multiomics data from The Cancer Genome Atlas linked CCL28 with RUNX3‐suppressed diffuse histological subtypes of non‐EBV/non‐MSI‐high GEA. Our data suggest that a high FOXP3+/CD8+ ratio at the invasive margin might indicate tumor immune escape via CCL28, particularly in the RUNX3‐methylated diffuse histological subtype.