bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital analysis of the human maxilla to enable semistandardized template tool reconstructions with free fibula transplants
Authors: Nobis Christopher-Philipp , Kübler Clara , Olmos Manuel , Schulz Katja , Glajzer Jacek , Backhaus Joy , Matta Ragai , Kesting Marco R. , Lutz Rainer 
Published: September 2024

Abstract
Objectives
This study analyzed the human maxilla to support the development of mean-value-based cutting guide systems for maxillary reconstruction, bridging the gap between freehand techniques and virtual surgical planning (VSP).

Materials and methods
This retrospective cohort study used routine CT scans. DICOM data enabled 3D modelling and the maxilla was divided into four regions: paranasal (R1), facial maxillary sinus wall (R2), zygomatic bone (R3) and alveolar process (R4). Surface comparisons were made with a reference skull. Statistical analyses assessed anatomical variations, focusing on mean distance (Dmean), area of valid distance (AVD), integrated distance (ID) and integrated absolute distance (IAD). The study addressed hemimaxillectomy defects for two-segmental reconstructions using seven defined bilateral points to determine segmental distances and angles.

Results
Data from 50 patients showed R2 as the most homogeneous and R4 as the most heterogeneous region. Significant age and gender differences were found in R3 and R4, with younger patients and females having more outliers. Cluster analysis indicated that males had R1 and R3 positioned anterior to the reference skull. The mean angle for segmental reconstruction was 131.24° ± 1.29°, with anterior segment length of 30.71 ± 0.57 mm and posterior length of 28.15 ± 0.86 mm.

Conclusions
Anatomical analysis supported the development of semistandardized segmental resection approaches. Although gender and anatomical differences were noted, they did not significantly impact the feasibility of mean-value-based cutting-guide systems.

Clinical relevance
This study provides essential anatomical data for creating cost-effective and efficient reconstruction options for maxillary defects, potentially improving surgical outcomes and expanding reconstructive possibilities beyond current techniques.
Performance of the Systemic Lupus Erythematosus Risk Probability Index (SLERPI) in a cohort of Colombian population
Authors: Celis-Andrade Mariana , Rojas Manuel , Rodríguez Yhojan , Calderon Juan Benjamín , Rodríguez-Jiménez Mónica , Monsalve Diana M. , Acosta-Ampudia Yeny , Ramírez-Santana Carolina 
Published: September 2024

Abstract
Objective
To evaluate the performance of the Systemic Lupus Erythematosus Risk Probability Index (SLERPI) in Colombian patients with systemic lupus erythematosus (SLE).

Methods
The Colombian cohort included 435 SLE patients and 430 controls with other autoimmune diseases (ADs). Clinical and serological data were collected, and SLE was indicated by SLERPI scores > 7. The American College of Rheumatology (ACR)-1997, Systemic Lupus International Collaborating Clinics (SLICC)-2012, and European League Against Rheumatism (EULAR)/ACR-2019 criteria were used as reference standards. The impact of overt polyautoimmunity (PolyA) on SLERPI performance was assessed. Additionally, multivariate lineal regression analysis was performed to evaluate the contribution of SLERPI features to the overall SLERPI score.

Results
SLE patients had higher SLERPI scores (P < 0.0001), with almost 90% meeting "definite" lupus criteria. Main factors influencing SLERPI included immunological disorder (β:44.75, P < 0.0001), malar/maculopapular rash (β:18.43, P < 0.0001), and anti-nuclear antibody positivity (β:15.65, P < 0.0001). In contrast, subacute cutaneous lupus erythematosus/discoid lupus erythematosus (β:2.40, P > 0.05) and interstitial lung disease (β:-21.58, P > 0.05) were not significant factors to the overall SLERPI score. SLERPI demonstrated high sensitivity for SLE, both for the overall SLE group and for those without overt PolyA (95.4% and 94.6%, respectively), but had relatively low specificity (92.8% and 93.7%, respectively). The model showed high sensitivity for hematological lupus (98.8%) and lupus nephritis (96.0%), but low sensitivity for neuropsychiatric lupus (93.2%). Compared to the ACR-1997, SLICC-2012 and EULAR/ACR-2019 criteria, SLERPI yielded the highest sensitivity and lowest specificity.

Conclusion
SLERPI efficiently identified SLE patients in a Colombian cohort, showing high sensitivity but low specificity. The model effectively distinguishes SLE patients, even in the presence of concurrent overt PolyA.

Key Points•SLERPI has a high sensitivity, but low specificity compared to ACR-1997, SLICC-2012 and EULAR/ACR-2019 criteria in the Colombian population.•Within the SLERPI score, immunological disorder, malar/maculopapular rash, and anti-nuclear antibody positivity are the strongest predictors of SLE.•SLERPI model can efficiently distinguish patients with SLE, regardless of concomitant overt PolyA.•SLERPI demonstrates high sensitivity in identifying hematological and nephritic subphenotypes of SLE.
Promoting higher education students’ self-regulated learning through learning analytics: A qualitative study
Authors: Kleimola Riina , Hirsto Laura , Ruokamo Heli 
Published: September 2024

AbstractLearning analytics provides a novel means to support the development and growth of students into self-regulated learners, but little is known about student perspectives on its utilization. To address this gap, the present study proposed the following research question: what are the perceptions of higher education students on the utilization of a learning analytics dashboard to promote self-regulated learning? More specifically, this can be expressed via the following threefold sub-question: how do higher education students perceive the use of a learning analytics dashboard and its development as promoting the (1) forethought, (2) performance, and (3) reflection phase processes of self-regulated learning? Data for the study were collected from students (N = 16) through semi-structured interviews and analyzed using a qualitative content analysis. Results indicated that the students perceived the use of the learning analytics dashboard as an opportunity for versatile learning support, providing them with a means to control and observe their studies and learning, while facilitating various performance phase processes. Insights from the analytics data could also be used in targeting the students’ development areas as well as in reflecting on their studies and learning, both individually and jointly with their educators, thus contributing to the activities of forethought and reflection phases. However, in order for the learning analytics dashboard to serve students more profoundly across myriad studies, its further development was deemed necessary. The findings of this investigation emphasize the need to integrate the use and development of learning analytics into versatile learning processes and mechanisms of comprehensive support and guidance.
How to Optimize Self-Assessment Accuracy in Cognitive Skill Acquisition When Learning from Worked Examples
Authors: Waldeyer Julia , Endres Tino , Roelle Julian , Baars Martine , Renkl Alexander 
Published: September 2024

AbstractThe present study was designed to understand and optimize self-assessment accuracy in cognitive skill acquisition through example-based learning. We focused on the initial problem-solving phase, which follows after studying worked examples. At the end of this phase, it is important that learners are aware whether they have already understood the solution procedure. In Experiment 1, we tested whether self-assessment accuracy depended on whether learners were prompted to infer their self-assessments from explanation-based cues (ability to explain the problems’ solutions) or from performance-based cues (problem-solving performance) and on whether learners were informed about the to-be-monitored cue before or only after the problem-solving phase. We found that performance-based cues resulted in better self-assessment accuracy and that informing learners about the to-be-monitored cue before problem-solving enhanced self-assessment accuracy. In Experiment 2, we again tested whether self-assessment accuracy depended on whether learners were prompted to infer their self-assessments from explanation- or performance-based cues. We furthermore varied whether learners received instruction on criteria for interpreting the cues and whether learners were prompted to self-explain during problem-solving. When learners received no further instructional support, like in Experiment 1, performance-based cues yielded better self-assessment accuracy. Only when learners who were prompted to infer their self-assessments from explanation-based cues received both cue criteria instruction and prompts to engage in self-explaining during problem-solving did they show similar self-assessment accuracy as learners who utilized performance-based cues. Overall, we conclude that it is more efficient to prompt learners to monitor performance-based rather than explanation-based cues in the initial problem-solving phase.
The Dynamic Nature of Emotions in Language Learning Context: Theory, Method, and Analysis
Authors: Wang Peng , Ganushchak Lesya , Welie Camille , van Steensel Roel 
Published: September 2024

AbstractIn current research, emotions in language use situations are often examined only at their starting and ending points, akin to observing the beginning and end of a wave, while neglecting their complex fluctuations in between. To fully comprehend the dynamics of emotions in language use situations, it is essential to delve into their intricate unfolding throughout their progression. This is particularly critical in the context of Second Language Acquisition (SLA), where emotional dynamics can significantly influence learning outcomes and proficiency. Drawing on existing empirical research and theories, we propose a novel interpretation rooted in complex dynamic systems theory (CDST) to elucidate the dynamic nature of emotions in language use situations. Furthermore, we suggest methodologies for capturing the complete dynamics of emotional and language behaviours, including an analysis of their dynamic interrelationships. By embracing a dynamic perspective, we can advance our understanding of interplay between emotions and language behaviours from epistemological theory to methodology and analysis, paving the way for future research in this field.
Modern extreme value statistics for Utopian extremes. EVA (2023) Conference Data Challenge: Team Yalla
Authors: Richards Jordan , Alotaibi Noura , Cisneros Daniela , Gong Yan , Guerrero Matheus B. , Redondo Paolo Victor , Shao Xuanjie 
Published: September 2024

AbstractCapturing the extremal behaviour of data often requires bespoke marginal and dependence models which are grounded in rigorous asymptotic theory, and hence provide reliable extrapolation into the upper tails of the data-generating distribution. We present a modern toolbox of four methodological frameworks, motivated by classical extreme value theory, that can be used to accurately estimate extreme exceedance probabilities or the corresponding level in either a univariate or multivariate setting. Our frameworks were used to facilitate the winning contribution of Team Yalla to the EVA (2023) Conference Data Challenge, which was organised for the 13$$^\text {th}$$thInternational Conference on Extreme Value Analysis. This competition comprised seven teams competing across four separate sub-challenges, with each requiring the modelling of data simulated from known, yet highly complex, statistical distributions, and extrapolation far beyond the range of the available samples in order to predict probabilities of extreme events. Data were constructed to be representative of real environmental data, sampled from the fantasy country of “Utopia”.
Violence in mass-mediated images and memory. Phenomenological account of prosthetic memories
Authors: Breazu Remus 
Published: September 2024

AbstractIn this paper, I analyse Alison Landsberg’s concept of prosthetic memories from a phenomenological perspective. Prosthetic memory, while sharing similarities with both personal and collective memory, is neither exclusively personal nor strictly collective, emerging as a product of new media in mass communication. According to Landsberg, prosthetic memories have four main characteristics: the recaller experiences them as firsthand accounts despite not personally living through the events, these memories often revolve around traumatic events, have a commodified form, and are ethically useful. Using Husserl’s theories on memory consciousness and image consciousness, and contemporary phenomenological research on violence, I provide a phenomenological account for the first three characteristics of prosthetic memory. The key factors contributing to their quasi-personal and quasi-collective nature lie, on the one hand, in the presence of imagistic violence and, on the other hand, in their mass-mediated image character.
Effects of a Creativity-Enhancement Intervention on Preservice Elementary Teachers’ Creativity in Computing Education
Authors: Novak Elena , Kuo Chia-Ling , Tassell Janet Lynne , Morris Grace 
Published: September 2024

AbstractRecently, creativity has been acknowledged for its importance in improving computer science learning and attitudes. However, very little is known about how to integrate creativity in preservice teacher computing education. Toward this end, we developed a creativity-enhancement intervention in an online Creative Computing instructional module to introduce preservice elementary teachers (N = 76) to the ideas of creativity in the context of computing education. Using a pre-/posttest quasi-experimental design, we examined the effects of the creativity-enhancement intervention on participants’ person-, process-, and Scratch product-related creativity compared to the same curriculum that did not include the creativity-enhancement intervention. Preservice elementary teachers who received the creativity-enhancement intervention reported significantly higher person- and process-related creativity and produced more creative Scratch projects than their peers who did not receive the intervention. When looking at the three creativity strands holistically, the study findings provide strong evidence that the intervention had a positive effect on preservice elementary teachers’ creativity in the context of computing education.
Protein Supplement Tolerability and Patient Satisfaction after Bariatric Surgery
Authors: Luijpers Cornelia Lianda H. , Nuijten Malou A. H. , Groenhuijzen Evi J. , van Hogezand Lilian L. , Monpellier Valerie M. , Eijsvogels Thijs M. H. , Hopman Maria T. E. 
Published: September 2024

Abstract
Purpose
Disproportional fat-free mass loss often occurs post-bariatric surgery, partly due to insufficient protein intake during the post-surgery recovery phase. We compared five protein-enhancing strategies (PES) on patient tolerability, satisfaction and protein intake.

Materials and Methods
Ninety-four participants, scheduled for bariatric surgery, were enrolled and allocated to either of the following: (1) whey powder, (2) hydrolysed collagen powder, (3) plant-based powder, (4) protein-rich products, (5) protein gel, or control. PES groups were instructed to add 30 g of powder or 2 gels or protein products to their diet. Patient satisfaction and tolerability were evaluated with questionnaires. Dietary intake was assessed prior to and during PES use.

Results
Seven patients dropped out (i.e. loss of contact, personal reasons or post-surgery complications) yielding an analytical cohort of 87 participants. The majority of patients (61%) did not experience dietary complaints from PES and could use PES ≥ 5 days of the week. PES non-usage was mainly related to taste dislike (58%). Hydrolysed collagen scored highest on tolerability and satisfaction: 86% of the participants could use HC ≥ 5 days and 71% were satisfied with the product. PES increased protein intake from 54.7 ± 21.5 g/day to 64.7 ± 23.4 g/day during the intervention (p = 0.002), which differed from the control group (+ 10.1 ± 24.5 g/day vs. − 6.3 ± 23.8 g/day for controls, p = 0.019). Whey showed the highest increase, namely + 18.3 ± 16.3 g/day (p = 0.009).

Conclusion
PES were tolerated by the majority of participants, and an improved protein intake with PES use was seen. However, the taste of the products could be improved to further enhance satisfaction and tolerability.

Graphical Abstract
New classes of p-adic pseudo-differential operators with negative definite symbols and their applications
Authors: Torresblanca-Badillo Anselmo , Bolaño-Benitez Edwin A. , Gutiérrez-García Ismael , Estala-Arias Samuel 
Published: September 2024

AbstractThis paper introduces new classes of p-adic operators representing m-dissipative pseudo-differential operators with negative definite symbols under certain conditions. We will study new types of semilinear problems and martingale problems associated with these operators, and we will prove that these pseudo-differential operators are the infinitesimal generators of strongly continuous contraction semigroups on $$L^2({\mathbb {Q}}_p^n)$$

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. Also, this article introduces new families of measures, resolvent of measures, positive definite measures, Feller semigroups, and Markov processes.
Metabolic Adaptation in Heart Failure and the Role of Ketone Bodies as Biomarkers
Authors: Foster Michael W. , Riley Joshua M. , Kaki Praneet C. , Al Soueidy Amine , Aligholiazadeh Ehson , Rame J. Eduardo 
Published: September 2024

Abstract
Purpose of Review
The development and progression of heart failure is characterized by metabolic and physiologic adaptations allowing patients to cope with cardiac insufficiency. This review explores the changes in metabolism in heart failure and the potential role of biomarkers, particularly ketone bodies, in staging and prognosticating heart failure progression.

Recent Findings
Recent insights into myocardial metabolism shed light on the heart’s response to stress, highlighting the shift towards reliance on ketone bodies as an alternative fuel source. Elevated blood ketone levels have been shown to correlate with the severity of cardiac dysfunction, emphasizing their potential as prognostic indicators. Furthermore, studies exploring therapeutic interventions targeting specific metabolic pathways offer promise for improving outcomes in heart failure.

Summary
Ketones have prognostic utility in heart failure, and potentially, an avenue for therapeutic intervention. Challenges remain in deciphering the optimal balance between metabolic support and exacerbating cardiac remodeling. Future research endeavors must address these complexities to advance personalized approaches in managing heart failure.
Real-World Experience of Clinical Outcomes of Microscopic Margin Positivity After Radical Gastrectomy from a Tertiary Cancer Center in Northeast India
Authors: Guha Akash , Sahewalla Ashutosh , Killing Dilip , Thakkar Manthan , Das Gaurav , Kalita Deep Jyoti , Talukdar Abhijit 
Published: September 2024

AbstractSurgical resection for gastric adenocarcinoma (GAC) remains the only potentially curative treatment, and the use of neoadjuvant and adjuvant therapy improves survival in patients with advanced gastric cancer. Margin-positive resection is a known poor prognostic factor. A retrospective observational study of patients undergoing radical gastrectomy of any type for GAC was done at a tertiary care cancer center in Northeast India. The study included patients who were operated on from 1 January 2017 to 31 December 2021 (5 years), and they were followed up to 31 March 2024. A total of 172 patients underwent gastrectomy of any type for GAC during the study period of which 13 patients were found to have microscopic positive (R1) histopathological margin (7.6%). The median age of the patients with positive margins was 48 years (range 27 to 69 years). The male-to-female ratio was 9:4. Ten patients (77%) had poorly differentiated or signet-ring cell carcinoma. The distal margin was the most frequent margin which was positive (84.6%). Neoadjuvant chemotherapy was used in only 23.1% patients. At the end of our study period, only 1 patient out of 13 patients was alive. Median disease-free survival (DFS) was 16.2 months (95% confidence interval 1.2 to 31.1 months). Median overall survival (OS) was 20.2 months (95% confidence interval 9.3 to 31.2 months). Patients who have microscopic positive margins after gastrectomy are found to have a high incidence of poorly differentiated or signet-ring cell carcinoma.
An analysis of mastodon adoption dynamics based on instance types
Authors: Sabo Eduard , Gesthuizen Tim , Bouma Kelvin J. A. , Karastoyanova Dimka , Riveni Mirela 
Published: September 2024

Abstract
Federated social networks have become an appealing choice as alternatives to mainstream centralized platforms. In the current global context, where the user’s activity on various social networks is monitored, influenced and manipulated, alternative platforms that offer the possibility of owning and controlling one’s own data are of great importance. Mastodon stands out among decentralized alternatives in the fediverse. In this study, we conduct a time-based dynamics analysis of various Mastodon instances, from popular ones to country-specific servers. Moreover, we conducted an analysis of registration account dynamics based on certain topics, such as academic, political and activism in general. Throughout the paper, we reveal the user adoption of Mastodon from multiple instances and metrics. Our results show a growth pattern of instances in terms of accounts in certain periods of time, and due to social events, reinforcing our assumption of it being already trusted as a decentralized platform. Our work holds significance in the wider context of studying and understanding the adoption rates of decentralized networks as ethical alternatives to centrally controlled ones.
How much Eurasian beaver activity is there in Italy? Using field signs to monitor and map a returned species
Authors: Mori Emiliano , Puttock Alan , Viviano Andrea , Mosini Andrea , Campbell-Palmer Roisin , Ancillotto Leonardo , Trentanovi Giovanni , Scarfò Manuel , Leoncini Fabio , Pontarini Renato , Mazza Giuseppe , Needham Robert 
Published: September 2024

AbstractAfter centuries of widespread extinction, the Eurasian beaver Castor fiber has recolonised most of its former extent of occurrence, following international and national protection laws, reintroduction programmes, and unauthorized releases. Beavers provide valuable ecosystem services and multiple benefits to native biodiversity, though their activity may trigger conflicts with humans, especially in highly modified landscapes. Therefore, it is important to monitor their range-expansion, particularly at the early stages of the colonization process. This study quantifies beaver presence in Central and Northern Italy, where reproduction was first detected in recent years after five centuries of absence. A mix of techniques including both direct and indirect signs of presence was adopted to assess the occurrence and status of beavers in the area, retrieving data for the application of density estimators and, thus, population estimates. We document that at least 16 reproductive events occurred between 2021 and early 2023, with at least 55 areas of activity, located across three rivers of Central Italy, corresponding to a minimum of 40 individuals. Seven to ten individuals (in at least 5 areas of activity) were also recorded in Northern regions, in continuity with the populations occurring in neighboring countries beyond the Alps. Given the fast range expansion by the species and the potential for conflict with human activities, alongside the efficiency and applicability of our approach, this type of beaver field survey should be adopted by wildlife managers and policy makers both in areas of established presence but also in potential expansion areas, to develop management plans and to figure out opportunities this returning native species may bring.