bluuebunny/crossref_metadata_2025_split huggingface dataset:
D2-40 Immunoreactivity of Lymphatic Vessels Endothelium and Representation of Lymphatic Vessels in the Liver of Human Fetuses of Different Gestational Age
Authors: Jović Marko , Nikolić Ivan , Todorović Vera , Petrović Aleksandar , Petrović Vladimir , Denčić Tijana 
Published: March 2017

Summary
In the reference literature, there are a few studies on the development of the lymphatic system in the liver, especially human. This study aims to establish the presence, time of appearance, distribution and representation of expression D2-40 molecule – a marker of lymph vessels endothelial cells during the fetal period of the human liver development.
The livers obtained from 20 human fetuses (10 male and 12 female), aged 12-37 gestational weeks, constituted our study material. Paraffin sections, 4 µm thick, were stained with hematoxylin and eosin for histological analysis, and with LSAB2/HRP method for immunohistochemistry using the D2-40 monoclonal antibody to mark lymphatic endothelial cells. The presence of lymphatic vessels was determined by morphometry, calculating their numerical and volume density.
The study showed that expression of D2-40 molecule was absent in the liver lymphatic vessels in the first trimester of development, while in the second trimester intensive D2-40 immunoreactivity was observed in the lymph vessels of the liver capsule, and low D2-40 immunopositivity of the lymph vessels in large portal spaces. In the third trimester, intensive D2-40 immunoreactivity was observed in the lymph vessels of the liver capsule and in the endothelium of numerous lymphatic vessels of various shape and size, located in the smaller and larger portal areas. Volume and numerical density of lymphatic vessels in the portal areas of the liver during fetal development increased from the second to the third trimester of pregnancy, which was proportional to the increase in volume density of the hepatic portal spaces. Based on the obtained results, a conclusion may be drawn that the lymph vessels in the liver can be identified in the first half of the second trimester, and their number was growing proportionally by the end of pregnancy.
Surgical Treatment of an Open Elbow Dislocation with Vascular Injury: A Case Report
Authors: Stojiljković Predrag , Jovanović Milan , Golubović Ivan , Mitković Milan , Mladenović Marko , Tošić Aleksandar 
Published: March 2017

SummaryOpen elbow dislocations with vascular injury are rare injuries and they most commonly occur after a fall from a high or in sports accidents. Close anatomic proximity of the joint to the neurovascular structures put them at risk of concomitant injury. The aim of this paper is to present the method of treatment of this severe injury.Herein we present a case of a female patient, 43 years old. She had suffered an open elbow dislocation with vascular injury as a result of a fall from the height of 1.5 meters. Seven hours after sustaining the injury and short preoperative preparation, reposition of the elbow, reconstruction of the vascular injury, adequate surgical treatment of the wound and external fixation of the elbow with the Mitković type external fixator were performed under general anesthesia. Four weeks after elbow stabilization with the external fixation, the external fixator was removed. The neurovascular status and final functional result of the treatment after six mounts were good.Urgent reposition, artery and vein reconstruction, and external fixation are essential in achieving good results in patients with open cubital dislocation accompanied with vascular injury. The Mitković type external fixator provides fast and stable fixation of the elbow after reposition and good conditions for wound care.
Performance Evaluation of Bucket based Excavating, Loading and Transport (BELT) Equipment – An OEE Approach
Authors: Mohammadi Mousa , Rai Piyush , Gupta Suprakash 
Published: March 2017

Abstract
Overall Equipment Effectiveness (OEE) has been used since last over two decades as a measure of performance in manufacturing industries. Unfortunately, enough, application of OEE in mining and excavation industry has not been duly adopted. In this paper an effort has been made to identify the OEE for performance evaluation of Bucket based Excavating, Loading and Transport (BELT) equipment. The conceptual model of OEE, as used in the manufacturing industries, has been revised to adapt to the BELT equipment. The revised and adapted model considered the operational time, speed and bucket capacity utilization losses as the key OEE components for evaluating the performance of BELT equipment. To illustrate the efficacy of the devised model on real-time basis, a case study was undertaken on the biggest single bucket excavating equipment – the dragline, in a large surface coal mine. One-year data was collected in order to evaluate the proposed OEE model.
Feed Material Influence on the Dynamics of the Suspended Screen at Its Steady State Operation and Transient States
Authors: Michalczyk Jerzy , Bednarski Łukasz , Gajowy Marek 
Published: March 2017

Abstract
The influence of the feed material on steady vibrations as well as on the transient resonance during the start-up and coasting of the suspended screen, was analysed in the hereby paper. The influence of the feed material presence on the possibility of performing the first half-turn of the vibrator was also established. The original, feed material simulation model reflecting its layer properties and diversification of feed particles vibrations along the screen riddle – specially developed for this aim – was applied in investigations.
Study of Loading and Running Characteristic of Hydraulic Support in Underhand Mining Face
Authors: Cheng Jing-Yi , Zhang Yi-Dong , Cheng Liang , Ji Ming , Gu Wei , Gao Lin-Sheng 
Published: March 2017

Abstract
According to complex geological conditions of working face E1108 in Xin-ji mine #2, loading and running characteristic of hydraulic support, influence of depression angle on mining pressure behaviors, as well as relation between advancing speed and the support loading were measured and analyzed. The results indicate that depression angle is inversely proportional to support resistance, in other words, larger depression angle area coincides with lower support resistance area. Moreover, support resistance is generally high when working face advancing speed is slow. Technologies for controlling hydraulic support stability such as improving advancing speed properly, controlling mining height and increasing support resistance are put forward based on research.
Compressive Lumbar Disc Hernia Spontaneously Disapeared in a Few Years - Case Report
Authors: Balasa D. , Ciufu Carmen , Baz R. , Hancu Anca 
Published: March 2017

Abstract
We present a patient with left compressive L5-S1 lumbar disc hernia in lateral reces and foramina revealed by high intensity pain (Visual Autologus Scale 7/10) and paresthesias on the left S1 dermatoma for 5 months. He refused surgery and followed conservative treatment with very good results after 6 months. The radicular S1 pain became of a small intensity (Visual Autologus Scale 2-3/10) and intermitent and after one year it completely disapeared. After 4 years he repeated the lumbar magnetic resonance imaging which proved the disapearance of the L5-S1 lumbar disc hernia.
Myocardial Contrast Agents – Safety Considerations and Clinical Efficacy in Stress Echocardiography
Authors: Maier Anca , Opris Maria Mihaela , Sirbu Voichita , Brinzaniuc Klara 
Published: March 2017

Abstract
Transthoracic echocardiographic examination is known to be a safe, non-invasive and reproducible method, used in every day clinical practice to obtain important information about cardiac structure and function. Unfortunately, a significant proportion of studies have highlighted the considerable technically difficultly in producing diagnostic images due to a poor acoustic window and more than 33% of patients undergoing stress echocardiography have suboptimal echocardiographic images. All these limitations have led to the use of contrast agents to improve the quality of standard ultrasound examination to provide a better delineation of left ventricle endocardial borders or to obtain information that cannot be achieved by using standard echocardiography, such as assessing myocardial microcirculation and therefore perfusion. This paper sought to review the clinical efficacy and safety of ultrasound contrast agents focusing on stress echocardiography.
A candidate reference method for serum potassium measurement by inductively coupled plasma mass spectrometry
Authors: Yan Ying , Han Bingqing , Zeng Jie , Zhou Weiyan , Zhang Tianjiao , Zhang Jiangtao , Chen Wenxiang , Zhang Chuanbao 
Published: March 2017

AbstractBackground:Potassium is an important serum ion that is frequently assayed in clinical laboratories. Quality assurance requires reference methods; thus, the establishment of a candidate reference method for serum potassium measurements is important.Methods:An inductively coupled plasma mass spectrometry (ICP-MS) method was developed. Serum samples were gravimetrically spiked with an aluminum internal standard, digested with 69% ultrapure nitric acid, and diluted to the required concentration. TheResults:The correlation coefficients between the measuredConclusions:The new ICP-MS method is specific, precise, simple, and low-cost, and it may be used as a candidate reference method for standardizing serum potassium measurements.
Serum complexed and free prostate-specific antigen (PSA) for the diagnosis of the polycystic ovarian syndrome (PCOS)
Authors: Diamandis Eleftherios P. , Stanczyk Frank Z. , Wheeler Sarah , Mathew Anu , Stengelin Martin , Nikolenko Galina , Glezer Eli N. , Brown Marshall D. , Zheng Yingye , Chen Yen-Hao , Wu Hsiao-Li , Azziz Ricardo 
Published: March 2017

AbstractBackground:Polycystic ovarian syndrome (PCOS) is a common cause of reproductive and metabolic dysfunction. We hypothesized that serum prostate-specific antigen (PSA) may constitute a new biomarker for hyperandrogenism in PCOS.Methods:We conducted a cross-sectional study of 45 women with PCOS and 40 controls. Serum from these women was analyzed for androgenic steroids and for complexed PSA (cPSA) and free PSA (fPSA) with a novel fifth- generation assay with a sensitivity of ~10 fg/mL for cPSA and 140 fg/mL for fPSA.Results:cPSA and fPSA levels were about three times higher in PCOS compared to controls. However, in PCOS, cPSA and fPSA did not differ according to waist-to-hip ratio, Ferriman-Gallwey score, or degree of hyperandrogenemia or oligo-ovulation. In PCOS and control women, serum cPSA and fPSA levels were highly correlated with each other, and with free and total testosterone levels, but not with other hormones. Adjusting for age, body mass index (BMI) and race, cPSA was significantly associated with PCOS, with an odds ratio (OR) of 5.67 (95% confidence interval [CI]: 1.86, 22.0). The OR of PCOS for fPSA was 7.04 (95% CI: 1.65, 40.4). A multivariate model that included age, BMI, race and cPSA yielded an area-under-the-receiver-operating-characteristic curve of 0.89.Conclusions:Serum cPSA and fPSA are novel biomarkers for hyperandrogenism in PCOS and may have value for disease diagnosis.
A physiologically based pharmacokinetic model to predict the superparamagnetic iron oxide nanoparticles (SPIONs) accumulation in vivo
Authors: Henrique Silva Adny , Lima Jr Enio , Vasquez Mansilla Marcelo , Zysler Roberto Daniel , Mojica Pisciotti Mary Luz , Locatelli Claudriana , Kumar Reddy Rajoli Rajith , Owen Andrew , Creczynski-Pasa Tânia Beatriz , Siccardi Marco 
Published: March 2017

AbstractSuperparamagnetic iron oxide nanoparticles (SPIONs) have been identified as a promising material for biomedical applications. These include as contrast agents for medical imaging, drug delivery and/or cancer cell treatment. The nanotoxicological profile of SPIONs has been investigated in different studies and the distribution of SPIONs in the human body has not been fully characterized. The aim of this study was to develop a physiologically-based pharmacokinetic (PBPK) model to predict the pharmacokinetics of SPIONs. The distribution and accumulation of SPIONs in organs were simulated taking into consideration their penetration through capillary walls and their active uptake by specialized macrophages in the liver, spleen and lungs. To estimate the kinetics of SPION uptake, a novel experimental approach using primary macrophages was developed. The murine PBPK model was validated against in vivo pharmacokinetic data, and accurately described accumulation in liver, spleen and lungs. After validation of the murine model, a similar PBPK approach was developed to simulate the distribution of SPIONs in humans. These data demonstrate the utility of PBPK modeling for estimating biodistribution of inorganic nanoparticles and represents an initial platform to provide computational prediction of nanoparticle pharmacokinetics.
Tourism e-services and Jewish heritage: a case study of Prague
Authors: Mitsche Nicole , Strielkowski Wadim 
Published: March 2017

AbstractOur paper describes the new potential for tourism e-services (smartphone apps and enhanced Internet platforms) for promoting the intangible cultural heritage in European destinations using the example of Prague’s Jewish heritage. Although quite a few tourism e-services are present in the tourism market in Prague, their full potential has not been exhausted.The paper shows that one of the ways how the intangible cultural heritage in European destinations can be promoted is through employing the apps for smartphones and tablets involving local myths and legends constituting the backbone of local cultural and religious traditions.Our research is based on the empirical results of the three stages of our own questionnaire survey conducted in Prague in May–August 2013 for assessing the revealed preferences of Prague’s residents and tourists for such apps and novel IT solutions.Our results demonstrate that a potential app should feature a narrative, a possibility to upload additional information, as well as interactive online maps. The app should be offered at both App Store and Android Market Play free of charge with embedded in-app purchases that might reach up to 3 EUR in additional payments.The paper tackles a top-notch field of electronic tourism (or e-tourism) that embeds the mobile technologies and the intangible cultural heritage approach. The results and outcomes might be useful not only for IT developers specialising in digital tourism but also for local stakeholders and residents.
The structural relationships of destination image, awareness, uniqueness and destination loyalty in periurban ecotourism destination
Authors: Jun Kim Sang 
Published: March 2017

Abstract
This study is designed to explore the conceptualization of ecotourism in order to expand the concept into ecotourism activities in our daily lives. To this end, the author proposes the ‘periurban ecotourism’ concept and conducts an empirical study with a focus on Nabari City, a small Japanese city with a well-preserved natural environment that has been attracting a number of visitors. In this study, destination image, awareness and uniqueness are presented as key independent variables to set directions for the development as a periurban ecotourism destination and to thereby develop a “theoretical periurban ecotourism model”, and four hypotheses for this study are examined. Findings from the examination reveal that destination image and awareness have a positive impact on overall satisfaction while destination uniqueness generates statistically significant result. In a group of first visitors, however, destination uniqueness appears to have a significant impact of some degree, with less influence than expected. In order to help redefine ecotourism and suggest a variety of research questions for ecotourism markets, it is necessary to conduct an empirical study covering “periurban ecotourism” and its conceptualization, motivation of ecotourists, and lifestyles from a more concrete perspective.
Tourist motivations in a heritage destination in Spain
Authors: Fernández Guzmán Antonio Muñoz , Pérez-Gálvez Jesús Claudio , López-Guzmán Tomás 
Published: March 2017

AbstractThe inscription of an area as World Heritage Site (WHS) is of utmost significance to preserve the historical and artistic heritage and at the same time, to encourage visits to the site. The purpose of this paper is to contribute to the study of the relationship between WHS and tourism by presenting the results of a research conducted in the city of Córdoba (Spain) which analyses the socio-demographic profile and motivations of tourists who visit this City, differentiating between domestic and foreign tourists. The main results of the research show the important educational level of respondent tourists, the significant number of countries of origin, the high motivation to learn about the heritage roots of the city, the importance of gastronomy as a part of its cultural identity and the high satisfaction of tourists. As a point of improvement, the results show the low level of overnight stays in the city.
Hydrological effects of the hydraulic structures constructed in the valley of the River Little Vistula in Poland from the mid-18th century to the present
Authors: Czaja Jakub 
Published: March 2017

Abstract
This study of the hydraulic structures constructed in the River Little Vistula (Mała Wisła) valley covers its western reach from the village of Strumień (Schwartzwasser) to the mouth of the River Przemsza. Its purpose was to assess the impact of these structures on changes in the conditions of runoff formation within the valley from the mid-18th century to the present. Historical materials (maps, sketches and plans) collected in the State Archives in Opole and Katowice were used in the study. Analyses of Austrian plane-table maps from the years 1763–1764 and 1861–1862 (1:28 800 scale) and of Prussian maps from the years 1827–1828 and 1881–1883 (1:25 000 scale) were also conducted. As a result of the study, the type and rate of hydraulic works were determined along with the techniques and methods used when constructing these structures in the 18th and 19th centuries. It was found that during the last 260 years, the main channel of the River Little Vistula moved within the meandering zone. Within the area of the Zarzecze and Mała Wisła settlements, a “new” River Vistula channel was formed during the flood in 1736, which shifted ca. 0.5–1.0 km to the south. The hydraulic structures which were constructed, mainly levees, caused water levels to rise excessively in the area during high water stages and the swollen waters often causing the levees to cave in, or to breach them. The river engineering work which was conducted also affected the formation of runoff in the valley of the River Little Vistula. It has been found that both anastomosis processes and river meandering were inhibited. In some channel reaches, temporal activation of deep erosion processes as well as channel shallowing were observed. Deep erosion reached up to 2 metres and channel shallowing up to 1 metre. These processes took place during river engineering work and the River Vistula bed took around a dozen years to stabilise following the completion of the work.
Cornus mas: a review on traditional uses and pharmacological properties
Authors: Hosseinpour-Jaghdani Fatemeh , Shomali Tahoora , Gholipour-Shahraki Sajedeh , Rahimi-Madiseh Mohammad , Rafieian-Kopaei Mahmoud 
Published: March 2017

Abstract
Medicinal plants that are used today have been known by people of ancient cultures around the world and have largely been considered due to their medicinal properties. Cornus mas L. (Cornelian cherry) is one of these medicinal plants with high level of antioxidant activity. Cornelian cherry is an attractive ornamental plant with delicious fruit having nutritional and therapeutic values. The main purpose of this paper is to present and summarize the pharmacological and therapeutic effects from researches done on Cornelian cherry in studies from 2000 to 2016. Information and findings in this review were taken from electronic journals in some websites including PubMed, Elsevier, ISI, Google scholar, SID and relevant books. C. mas L. is important in terms of decoration and is used in traditional medicine to treat diarrhea, inflammatory bowel disease, cholera, fever, malaria, kidney stones, urinary tract infections, cancer, bleeding and heat stroke. Several studies have shown that Cornelian cherry fruit plays an important role in prevention of atherosclerosis, blood sugar, lipid profiles and reduction of fat accumulation in the liver. Cornelian cherry has antimicrobial, antiparasitic, anti-inflammatory, antioxidant and anticancer effects as well as protecting liver, kidney and cardiovascular system. Using Cornelian cherry in pharmaceutical and food industries has caused fantastic value of this plant. Pharmaceutical properties of Cornelian cherry seeds, fruits, leaves and stems have led the need of further studies to explore the other unknown effects or review mechanism of its pharmacological effects for preparation of new drugs.
When natives became Africans: A historical sociolinguistic study of semantic change in colonial discourse
Authors: Fitzmaurice Susan 
Published: March 2017

AbstractThe wordnativeis a key term in nineteenth-century British colonial administrative vocabulary. The question is how it comes to be central to the classification of indigenous subjects in Britain’s southern African possessions in the early twentieth century, and how the word is appropriated by colonial citizens to designate the race of indigenous subjects. To answer the question, I construct a semasiological history ofnativeas a word that has to do with the identification of a person with a place by birth, by residence or by citizenship. I track the manner in which speakers invest old words with new meanings in specific settings and differentiate among them in different domains. In the case ofnative, a signal keyword is recruited to do particular work in several contemporaneous discourses which take different ideological directions as the nature of the involvement of their speakers changes. The result is a particularly complicated word history, and one which offers a clue to the ways in which colonial rhetoric is domesticated in specific settings at the very same time as the colonising power eschews it in the process of divesting itself of its colonies.
Delivery modes in case of fetal malformations
Authors: Wataganara Tuangsit , Grunebaum Amos , Chervenak Frank , Wielgos Miroslaw 
Published: March 2017

AbstractAn estimated 276,000 babies die within 4 weeks of birth every year, worldwide, from congenital anomalies. Better quality ultrasound screening can increase the detection of these fetal malformations in the prenatal period. Prenatal counseling for the pregnant woman and her family, regarding the nature of the disease and prognosis is necessary. Options for management in prenatal, perinatal, intrapartum, neonatal, and childhood periods need to be thoroughly discussed, so that the family can make an informed decision. A multidisciplinary approach is usually needed once a decision has been made to optimize fetal outcome, to plan for the timing and location as well as the mode of delivery. In most of the cases, vaginal delivery can be attempted. An elective cesarean delivery should be reserved for maternal concern of dystocia, certain fetal conditions that cesarean delivery will optimize perinatal outcome, or if the parents have a psychosocial determination to have a live-born infant.