bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of lysophosphatidic acid using a hydrogel or collagen sponge carrier on bone healing in dogs
Authors: Martinez Steven , Karin Norman , Lin Genyao , Tarasevich Barbara , Pool Roy , Might Kelly 
Published: June 2016

SummaryObjectives: The purposes of this study were to determine: 1) the efficacy of polycaprolac-tone-g-polyethylene glycol (PCL-g-PEG) and polylactic-co-glycolic acid (PLGA-g-PEG) hydrogels and an absorbable collagen sponge (ACS) as carriers for lysophosphatidic acid (LPA), 2) the effect of LPA on bone healing in dogs, and 3) the ideal dose of LPA to maximally stimulate bone healing.Methods: Bilateral ulnar ostectomies were performed on purpose bred dogs. Control defects were filled with a PCL-g-PEG or PLGA-g-PEG hydrogel, or a saline soaked ACS. Contralateral defects were filled with a PCL-g-PEG or PLGA-g-PEG hydrogel, or an ACS with each carrying differing concentrations of an LPA solution. Dual-energy X-ray absorptiometry (DXA) was performed. Total bone area (TBA), mineral density (BMD), and mineral content (BMC) were determined at each time point. Relationships between the effect of treatment over time on TBA, BMC and BMD were determined.Results: Phase 1 - There was no significant difference in DXA-based TBA (p = 0.09), BMC (p = 0.33), or BMD (p = 0.74) over time between LPA treatments, or between the LPA treated and control groups TBA (p = 0.95), BMC (p = 0.99), or BMD (p = 0.46). Phase 2 - There was no significant difference over time between LPA treatments in DXA-based TBA (p = 0.33), BMC (p = 0.45), or BMD (p = 0.43), or between the LPA treated and control groups TBA (p = 0.94), BMC (p = 0.38), or BMD (p = 0.17). Phase 3 - There was no significant difference over time between LPA treatments in DXA-based TBA (p = 0.78), BMC (p = 0.88), or BMD (p = 0.35), or between the LPA treated and control groups TBA (p = 0.07), BMC (p = 0.85), or BMD (p = 0.06). There was a significant increase in TBA (p <0.0001) and BMC (p = 0.0014), but a significant decrease in BMD (p <0.0001) was noted over time when all groups were combined.Clinical significance: Although LPA has shown promise as an osteoinductive agent in research, its performance as a bone graft substitute, as utilized in this study, is unsupported. Further studies are necessary to determine the incorporation and elution kinetics of LPA from the PLGA-g-PEG hydrogel and from an ACS. Hydrogels may have clinical applications for delaying or preventing bone formation.
The morphosemantics of Spanish indefinites
Authors: Martí Luisa 
Published: June 2016

I analyze the Spanish indefinites algún and algunos as a paucal and a greater paucal determiner, respectively, contrary to the common assumption that views the former as singular and the latter as plural. I use Harbour’s (2014) feature [±additive], and the possibility of repeating that feature, in order to do so. I propose a transparent word-internal compositional analysis of the two determiners, where alg- contributes [−additive] to both of them. I discuss consequences for the semantics of morphological plurality in nouns and for the analysis of ignorance implicatures.
The Effect of the Presence of Fibromyalgia on Common Clinical Disease Activity Indices in Patients with Psoriatic Arthritis: A Cross-sectional Study
Authors: Brikman Shay , Furer Victoria , Wollman Jonathan , Borok Sara , Matz Hagit , Polachek Arik , Elalouf Ofir , Sharabi Amir , Kaufman Ilana , Paran Daphna , Elkayam Ori 
Published: June 2016

Objective.To study the effect of the presence of fibromyalgia (FM) on common clinical disease activity indices in patients with psoriatic arthritis (PsA).Methods.Seventy-three consecutive outpatients with PsA (mean age 51.7 yrs; 42 females, 57.5%) were enrolled in a prospective cross-sectional study. FM was determined according to American College of Rheumatism criteria (2010 and 1990). All patients underwent clinical evaluation of disease activity and completed the Health Assessment Questionnaire (HAQ), the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), the Dermatology Life Quality Index, and the Leeds Enthesitis Index (LEI). Disease activity was evaluated using the Composite Psoriatic Disease Activity Index (CPDAI), minimal disease activity (MDA), and the Disease Activity Index for Psoriatic Arthritis (DAPSA) scores.Results.The overall prevalence of FM was 17.8% (13 patients), and all but 1 were women (12 patients, 92.3%, p = 0.005). CPDAI and DAPSA scores were significantly higher in patients with coexisting PsA and FM (9.23 ± 1.92 and 27.53 ± 19.23, respectively) than in patients with PsA only (4.25 ± 3.14 and 12.82 ± 12.71, respectively; p < 0.001 and p = 0.003). None of the patients with FM + PsA met the criteria for MDA, whereas 26 PsA-only patients did (43.3%, p = 0.003). HAQ, BASDAI, and LEI scores were significantly worse in patients with PsA and associated FM.Conclusion.Coexisting FM is related to worse scores on all tested measures in patients with PsA. Its influence should be taken into consideration in the treatment algorithm to avoid unnecessary upgrading of treatment.
La réponse pénale à l’usage des stupéfiants, entre politique répressive et mesures à caractère sanitaire et pédagogique
Authors: Ogrodnik Marysia , Kopp Pierre-Alexandre 
Published: June 2016

La loi de 1970 « relative aux mesures sanitaires de lutte contre la toxicomanie et à la répression du trafic et de l’usage illicite de substance vénéneuses » constitue encore le principal cadre légal des politiques prohibitionnistes en France. Elle laisse pourtant dans un flou juridique la distinction entre usage récréatif et toxicomanie d’une part, et d’autre part entre consommateur.trice et trafiquant.e, ce qui conduit à un relatif arbitraire des condamnations.
Les droits de l’homme et la pensée politique de gauche au Brésil
Authors: Lefort Claude 
Published: June 2016

La gauche brésilienne a longtemps été dédaigneuse de la question des droits de l’homme jugée à l’aune des « droits formels » et de la « démocratie bourgeoise ». Comme le montre Luciano de Oliveira c’est durant la dictature militaire que la gauche va tout à la fois rompre avec le marxisme révolutionnaire et se doter d’une nouvelle culture politique prenant en compte la question du droit. La réflexion sur l’histoire de ces transformations conduit à s’interroger sur la façon dont la dictature reçut à ses débuts de nombreux appuis populaires, comment de larges secteurs légitimèrent les multiples violations des droits de l’homme à l’encontre des opposants. L’avènement d’un régime démocratique se traduisit par un souci nouveau de l’égalité entre les citoyens et partant suscita un regard nouveau sur l’usage de la torture et de la violence.
La réélection d’Evo Morales à la présidence de la Bolivie
Authors: Lavaud Jean-Pierre 
Published: June 2016

Evo Morales a été réélu pour la troisième fois consécutive président de l’État plurinational de Bolivie avec le score officiel de 61,5 % des suffrages. Et les candidats présentés par son parti, le Movimiento al socialismo (MAS), ont gagné les 2/3 des sièges de l’ Asamblea Legislativa Plurinacional (ALP), tant au sein de la Chambre des députés qu’au Sénat. Ce résultat flatteur s’explique en partie par le charisme du candidat et la bonne santé économique du pays – principalement causée par le cours avantageux des matières premières que le pays exporte – mais l’ampleur du succès tient aux nombreuses fraudes orchestrées par le pouvoir exécutif avec la complicité du Tribunal supremo electoral .
Le lieu de la dialectique hégélienne dans la pensée de Paul Ricœur
Authors: Picardi Roberta 
Published: June 2016

Cet essai reconstruit les principales étapes de la confrontation de Ricœur avec la dialectique de Hegel, depuis ses premières notes manuscrites sur « Hegel et la négativité » jusqu’à l’essai de 1975, « Le lieu de la dialectique ». L’objectif que l’on vise est triple. Il s’agit tout d’abord de reconstruire dans sa genèse l’effort ricœurien de « régionalisation » de la dialectique hégélienne, dont les raisons ne peuvent pas être réduites à un refus générique des effets de totalisation systématique de l’identification hégélienne entre négation et médiation. Le deuxième objectif est la mise en relève des raisons exogènes et endogènes qui sous-tendent l’élargissement et le déplacement que le lieu de la dialectique hégélienne subit, suite à la greffe ricœurienne de l’herméneutique sur la phénoménologie. Enfin, on vise à déterminer la place variable que la dialectique hégélienne occupe par rapport aux autres « dialectiques » qui nourrissent le style dialectique de la philosophie de Ricœur, de la « dialectique » du paradoxe de Kierkegaard et de la dialectique des cinq genres du Sophiste – telles qu’il les interprète – à la dialectique nabertienne entre acte et signes.
Construire le street workout , faire le genre : snapshots ethnographiques sur le bricolage identitaire engagé par les pratiquant-e-s de « fitness des rues »
Authors: Mueller Alain 
Published: June 2016

Dans cet article, je m’intéresse au travail de mobilisation de différentes logiques et catégories par les adeptes de street workout , une nouvelle forme d’activité sportive urbaine, pour rationaliser leur pratique, la mettre en récit et la promouvoir. J’entreprends cet examen en m’intéressant plus particulièrement (1) au genre, que je conceptualise comme une forme de travail, engagé de manière routinière et mobilisant un ensemble de ressources (logiques, représentations et catégories) préexistantes, et dont le résultat participe à la consolidation ou à la transformation de ces dernières ; et (2) aux modalités de son entremêlement dans un bricolage identitaire plus large, participant de la mobilisation conjointe de différents registres d’identification et de classification, comme l’ethnicité, le milieu, la territorialité et les groupes de pratiquants à différentes échelles (communauté imaginée de pratiquant-e-s à échelle globale, groupes de pairs locaux). Dans un premier temps, je propose une contextualisation historique du street workout, avec une attention particulière portée aux usages, aux trajectoires et aux effets de différentes catégories et des registres d’identification et de classification auxquels elles renvoient. Dans un second temps, je poursuis cette analyse en m’intéressant plus spécifiquement aux discours tenus par les adeptes de street workout pour promouvoir leur activité sportive et qui, pour des raisons que j’explique, constituent souvent le terreau sur lequel vient s’articuler plus directement la mise en récit du genre. Je montre ainsi que ces discours participent souvent d’un encouragement actif à la participation des femmes au street workout, et plus largement d’une posture pouvant être qualifiée, dans une certaine mesure, de (pro-)féministe. Je m’intéresse ensuite aux stratégies déployées pour tenter de pallier le décalage entre cette logique d’encouragement de la pratique des femmes et le fait que la discipline demeure néanmoins pratiquée majoritairement par des hommes. Je m’intéresse enfin aux arguments mobilisés par les pratiquant-e-s pour expliquer la persistance de ce décalage, et montre que ceux-ci laissent transparaître une forme de mise à l’épreuve de la posture (pro-)féministe par des logiques et des représentations qui les précèdent, et notamment certains stéréotypes de genre.
Action sociale et service public
Authors: Lafore Robert 
Published: June 2016

L’action sociale entretient des rapports complexes avec le « service public ». Constitué à la fois de structures publiques et d’organismes de droit privé, ce dualisme organique a été dépassé par le développement d’une police administrative visant non les gestionnaires mais leurs activités circonscrites dans les notions d’« établissements » et de « services ». À l’heure où tant les services publics que les activités privées qui lui sont associées connaissent des mutations convergentes du fait du centrage de l’action sociale sur « l’usager » et du développement de méthodes de management pratiquant une forme de syncrétisme fonctionnel entre activités publiques et marché, les évolutions en cours amènent à s’interroger sur les voies et moyens de la production du « bien commun » qu’ont encore en partage tant les personnes publiques que les groupements intermédiaires qui visent de concert l’intérêt général et l’utilité sociale.
Os Incentivos dos Diferentes Tipos de Dupla Listagem ao Conservadorismo Contábil
Authors: Castro Elizangela Lourdes de , Costa Fábio Moraes da , Reis Anderson De Oliveira 
Published: June 2016

No período 1998-2007, houve um aumento do número de empresas brasileiras que emitiram valores mobiliários em outros mercados, especialmente o norte-americano. Em virtude disso, este trabalho teve como objetivo verificar se a opção das empresas brasileiras listadas na BM&FBOVESPA pela dupla listagem no mercado norte americano criou incentivos para aumentar o grau de conservadorismo dessas empresas. Para alcançar este objetivo, foram testadas três hipóteses em função do tipo de listagem: 1 – Aderir à dupla listagem incentiva o conservadorismo das empresas; 2 – Aderir aos níveis II e III incentiva o conservadorismo das empresas. 3 – Aderir à listagem nos níveis III e 144A incentiva o grau de conservadorismo das empresas. Para medir o grau de conservadorismo foram utilizados os modelos de Basu (1997) e Ball e Shivakumar (2005), estimados em painel, para o período de 1998 a 2007. Os resultados encontrados nos testes mostraram que não houve mudança no nível de conservadorismo em nenhum dos tipos de dupla listagem das empresas no mercado norte-americano. Isto permite inferir que a dupla listagem não incentivou a um comportamento mais conservador por parte daquelas empresas. Em relação à amostra de todas as empresas, apenas no modelo de Ball e Shivakumar (2005) os resultados indicaram presença de conservadorismo.
Comparison of Head Elevation Protocols Following Femoral Artery Sheath Removal After Coronary Angiography
Authors: Olson Nancy C. 
Published: June 2016

ObjectivesTo compare 2 standard protocols for head elevation following removal of a femoral artery sheath after coronary angiography and their effects on bleeding complications and reported levels of back pain. One protocol involved flat supine bed rest; the other allowed progressive head elevation.MethodsA prospective comparative study of 80 adult patients undergoing coronary angiography via the femoral approach. The Numeric Rating Scale was used as the measure of reported pain.ResultsNo bleeding complications occurred in either group. Both groups had very low mean pain scores. Repeated-measures analysis demonstrated that the experience of pain differed significantly over time by location (F5,70 = 3.864, P = .004), with a notable decrease in pain scores more than 1 hour after sheath removal at the location that used the progressive head elevation protocol. Patients’ satisfaction scores after discharge did not differ significantly between the 2 groups. Patients with a history of chronic back pain had consistently higher pain scores, but those pain scores did not differ significantly by location (or protocol).ConclusionsIt appears that using a progressive head-elevation protocol within the first 3 hours after diagnostic angiography is not associated with an increased risk of bleeding complications at the access site and warrants further exploration in the mitigation of back pain associated with prolonged supine bed rest.
Patient Experiences Using an Inpatient Personal Health Record
Authors: Prey Jennifer , Wilcox Lauren , Sackeim Alexander , Restaino Susan , Raza Syed , Bakken Suzanne , Feiner Steven , Hripcsak George , Vawdrey David , Woollen Janet 
Published: June 2016

SummaryTo investigate patients’ experience using an inpatient personal health record (PHR) on a tablet computer to increase engagement in their hospital care.We performed observations and conducted semi-structured interviews with 14 post-operative cardiac surgical patients and their family members who received an inpatient PHR. Themes were identified using an inductive coding scheme.All participants responded favorably to having access to view their clinical information. A majority (85.7%) of participants used the application following an initial training session. Patients reported high satisfaction with being able to view their hospital medications and access educational materials related to their medical conditions. Patients reported a desire to view daily progress reports about their hospital stay and have access to educational information about their postacute recovery. In addition, patients expressed a common desire to view their diagnoses, laboratory test results, radiology reports, and procedure notes in language that is patient-friendly.Patients have unmet information needs in the hospital setting. Our findings suggest that for some inpatients and their family members, providing personalized health information through a tablet computer may improve satisfaction, decrease anxiety, increase understanding of their health conditions, and improve safety and quality of care.
The Notion ‘Nature’ as Emerging from N Kazantzakis Works and School Books of Life Sciences: A Case Study
Authors: Maria Kalathaki 
Published: June 2016

<p>People struggled to explain the world around them and to build on the achievements of science and technology in order to improve the quality of life. The first questions raised for the properties and the beginnings of the external world, concerning all those perceived by human senses for the Nature. The ancient Greek spirit realized the Nature, organic or inorganic, as living, animated wholeness, as a universe. As Philosophy and Science developed, revealed the greatness of the creation of the world, cultivated the notion of the human superiority, with numerous cases of interpretation of the Nature based on the human creature. The concept of ‘Nature’ is intertwined with social choices and management practices. Environmental Ethics is education of values which allows the development of mechanisms that drive changes to attitudes and values, broaden and deepen the pedagogical dimension of theories of science and sociology. </p><p>In this paper is studied the issue of ‘Nature’ in a didactic research, through the philosophical approach of values of Educational of the Sustainable Development. The notion of Nature has significantly replaced by the term of ‘Environment’ attributing ecological, economic, scientific, aesthetic, existential, spiritual value. The research in this case study, carried out in the literature, with N Kazantzakis works and school books of Biology and Environmental Sciences, in order to clarify terms linked to the scientific and philosophical concept of ‘Nature’ and the ‘nature’ of the things. The educational intervention is a negotiation between literature and issues of the environmental science. This research materialized in the stage of preparing a seminar for science teachers on the teaching issues of ‘Nature’ and ‘nature’ of the things. In order to prepare the trainees, in a peer learning activity of N Kazantzakis works, to extract those fragments are related to the term “Nature’ from their point of view, and at the end, they co-form a theatrical lectern where they read the excerpts, in a structural and theatric way.</p>
The Impact of IFRS 8 on Segment Disclosure Practice: Panel Evidence from Italy
Authors: Lucchese Manuela , Di Carlo Ferdinando 
Published: June 2016

The study examines the effectiveness of IFRS 8, effective since 2009, in relation to both the magnitude of segment disclosures and the firms' characteristics that might affect the disaggregated disclosure policies decisions, on Italian listed companies during the period 2008-2012.The results show that on average, the new standard did not lead to relevant changes in the segment disclosures as previously stated under IAS 14R, thus demonstrating inconsistency with the expectations of the IASB. In addition, we demonstrated, by employing a fixed-effect regression, that the magnitude of segment disclosure is negatively associated with growth rate, size, profitability and ownership diffusion.The present study contributes to the extant literature in terms of the PIR review, discussing the effectiveness of IFRS 8 some years after adoption, and not merely considering the first year, where the results may be affected by the learning curve effect in countries less familiar with Anglo-Saxon accounting.
Subchondral haematoma
Authors: Austin Steve , Back Diane , Wharton Rupert 
Published: June 2016

SummaryHaemophilic arthropathy is a complex multifactorial disorder that poses significant challenges to both the treating haematologist and arthroplasty surgeon. Its pathogenesis is incompletely understood. Recent literature has concentrated on the toxic effects of iron and the characteristic inflammatory synovitis. Discussion of the role of subchondral bleeding in joint damage has been neglected. A case of haemophilic arthropathy with extensive evidence of subchondral bleeding and related osteochondral destruction is presented. Result: The relevance of this mechanical pathway in the future management of haemophilic arthropathy is discussed with reference to recent literature. Conclusion: Clinicians should consider its importance when deciding whether to manage patients expectantly or with prophylactic factor replacement.
Identification and Characterization of Human Endometrial Mesenchymal Stem/Stromal Cells and Their Potential for Cellular Therapy
Authors: Darzi Saeedeh , Werkmeister Jerome A. , Deane James A. , Gargett Caroline E. 
Published: June 2016

Abstract

Summary
Human endometrium is a highly regenerative tissue, undergoing more than 400 cycles of proliferation, differentiation, and shedding during a woman' reproductive life. Adult stem cells, including mesenchymal stem/stromal cells (MSCs), are likely responsible for the immense cellular turnover in human endometrium. The unique properties of MSCs, including high proliferative ability, self-renewal, differentiation to mesodermal lineages, secretion of angiogenic factors, and many other growth-promoting factors make them useful candidates for cellular therapy and tissue engineering. In this review, we summarize the identification and characterization of newly discovered MSCs from the human endometrium: their properties, the surface markers used for their prospective isolation, their perivascular location in the endometrium, and their potential application in cellular therapies.

Significance
The endometrium, or the lining of uterus, has recently been identified as a new and accessible source of mesenchymal stem cells, which can be obtained without anesthesia. Endometrial mesenchymal stem cells have comparable properties to bone marrow and adipose tissue mesenchymal stem cells. Endometrial mesenchymal stem cells are purified with known and novel perivascular surface markers and are currently under investigation for their potential use in cellular therapy for several clinical conditions with significant burden of disease.