bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: High‐Performance Na3V2(PO4)3/C Cathode for Sodium‐Ion Batteries Prepared by a Ball‐Milling‐Assisted Method.
Authors: Klee Rafael , Aragon Maria Jose , Alcantara Ricardo , Tirado Jose L. , Lavela Pedro 
Published: August 2016

AbstractThe title composite cathode material for sodium ion batteries is prepared by wet‐ball‐milling of mixtures of NH4VO3, NaH2PO4, citric acid, and EtOH for 24 h at 300 rpm in air, followed by heating at 800 °C for 8 h under Ar.
ChemInform Abstract: One Novel Near‐Infrared Ytterbium Metal—Organic Framework Based on an Unprecedented [Yb6(μ2‐OH)2 (μ3‐OH)6]10+ Cluster.
Authors: Wen Guo‐Xuan , Wang Jian‐Fang , Wu Xue‐Qian , Pan Li‐Qing , Li Dong‐Sheng 
Published: August 2016

AbstractColorless crystals of [Yb3(pyc)2.5(OH)4(bipy)] (H2pyc: pyridine‐carboxylic acid) are hydrothermally synthesized from aqueous mixtures of Yb(NO3)3, H2pyc, bipy, and NaOH (autoclave, 180 °C, 96 h, 58% yield).
ChemInform Abstract: Zirconocenes vs. Alanes: A Crucial Choice of the Allyl Source for Highly Diastereoselective Allylzincation of Nonracemic Chiral Imines.
Authors: Coffinet Michael , Jaroschik Florian , Vasse Jean‐Luc 
Published: August 2016

AbstractA diastereoselective synthesis of enantioenriched homoallyl amine derivatives (III) and (V) is developed.
ChemInform Abstract: A Two‐Component Alkyne Metathesis Catalyst System with an Improved Substrate Scope and Functional Group Tolerance: Development and Applications to Natural Product Synthesis.
Authors: Schaubach Sebastian , Gebauer Konrad , Ungeheuer Felix , Hoffmeister Laura , Ilg Marina K. , Wirtz Conny , Fuerstner Alois 
Published: August 2016

AbstractA catalyst formed in situ upon mixing of a trisamidomolybdenum alkylidyne complex and a trisilanol derivative is highly efficient in metathesis reactions of a series of model compounds comprising primary, secondary or phenolic ‐OH groups, as well as challenging (bis)propargylic substrates.
ChemInform Abstract: Development and Applications of Transesterification Reactions Catalyzed by N‐Heterocyclic Olefins.
Authors: Bluemel Marcus , Noy Janina‐Miriam , Enders Dieter , Stenzel Martina H. , Nguyen Thanh V. 
Published: August 2016

AbstractN‐Heterocyclic olefins represent a novel class of transesterification catalysts.
ChemInform Abstract: Construction of Stereogenic α,α‐Disubstituted Cycloalkanones via 1° Amine Thiourea Dual Catalysis: Experimental Scope and Computational Analyses.
Authors: Kang Jun Yong , Johnston Ryne C. , Snyder Kevin M. , Cheong Paul Ha‐Yeon , Carter Rich G. 
Published: August 2016

AbstractThe reaction mechanism, including the catalysts′ features responsible for the stereoselectivity, is extensively investigated.
ChemInform Abstract: N‐Heterocyclic Carbene‐Catalyzed Convenient Benzonitrile Assembly.
Authors: Jia Qianfa , Wang Jian 
Published: August 2016

AbstractAn oxidative NHC‐catalyzed cyclization of ketonitriles (I) and (IV) with α,β‐unsaturated aldehydes provides a novel method for the synthesis of functionalized benzonitriles.
ChemInform Abstract: Enantio‐ and Diastereoselective Cross‐Annulation of Enal and Ketone with New Chiral Bicyclic N‐Heterocyclic Carbene Catalysts.
Authors: Hasegawa Momo , Yoshida Kazuhiro , Yanagisawa Akira 
Published: August 2016

AbstractA series of 17 new chiral bicyclic imidazolium salts are tested as catalysts for the enantio‐ and diastereoselective cross‐annulation reaction of cinnamaldehyde (I) and trifluoroacetophenone (II).
ChemInform Abstract: Regioselective Synthesis of Naphtho‐Fused Heterocycles via Palladium(0)‐Catalyzed Tandem Reaction of N‐Tosylhydrazones.
Authors: Ngo Thang Ngoc , Dang Tuan Thanh , Villinger Alexander , Langer Peter 
Published: August 2016

AbstractThe tandem process involves the cross‐coupling reaction of N‐tosylhydrazones with the dibromide partner followed by intramolecular 5‐exo‐trig and 3‐exo‐trig cyclizations, ring opening, and β‐hydride elimination.
ChemInform Abstract: Friedel—Crafts Alkylation of Indoles with p‐Quinols: The Role of Hydrogen Bonding of Water for the Desymmetrization of the Cyclohexadienone System.
Authors: Garcia‐Garcia Carolina , Ortiz‐Rojano Laura , Alvarez Susana , Alvarez Rosana , Ribagorda Maria , Carreno M. Carmen 
Published: August 2016

Abstract5‐Indolyl substituted 4‐hydroxy‐4‐methyl‐2‐cyclohexanone systems are prepared in a high π‐facial diastereoselective manner.
ChemInform Abstract: Curtius‐Like Rearrangement of an Iron—Nitrenoid Complex and Application in Biomimetic Synthesis of Bisindolylmethanes.
Authors: Li Dashan , Wu Ting , Liang Kangjiang , Xia Chengfeng 
Published: August 2016

AbstractAn iron(II)‐catalyzed Curtius‐like rearrangement involving the decomposition of an iron‐nitrenoid complex generated by cleavage of N—O bonds of functionalized heteroauxin hydroxamates is investigated.
ChemInform Abstract: Base‐Controlled Cu‐Catalyzed Tandem Cyclization/Alkynylation for the Synthesis of Indolizines.
Authors: Oh Kyung Hwan , Kim Seong Min , Park Sun Young , Park Jin Kyoon 
Published: August 2016

AbstractThe title reaction of pyridines having an alkynyl side chain proceeds via a 5‐endo‐dig aminocupration, followed by coupling of the copper intermediate with an alkynyl bromide.
ChemInform Abstract: Regioselectively Controlled Synthesis of N‐Substituted (Trifluoromethyl)pyrimidin‐2(1H)‐ones.
Authors: da Silva Andreia M. P. W. , da Silva Fabio M. , Bonacorso Helio G. , Frizzo Clarissa P. , Martins Marcos A. P. , Zanatta Nilo 
Published: August 2016

AbstractConditions for the selective and high‐yielding preparation of either 1,4‐ or 1,6‐regioisomers of the title products are elaborated starting from 4‐substituted 1,1,1‐trifluoro‐4‐methoxybut‐3‐en‐2‐ones and nonsymmetric ureas or urea sulfates, respectively.
ChemInform Abstract: Metal Free C—H Functionalization of Diazines and Related Heteroarenes with Organoboron Species and Its Application in the Synthesis of a CDK Inhibitor, Meriolin 1.
Authors: Thatikonda Thanusha , Singh Umed , Ambala Srinivas , Vishwakarma Ram A. , Singh Parvinder Pal 
Published: August 2016

AbstractA broad range of hetarenes is coupled with various aryl and hetaryl boronic acids to form the products in moderate yields.
ChemInform Abstract: Regioselective 2‐Amination of Polychloropyrimidines.
Authors: Smith Sean M. , Buchwald Stephen L. 
Published: August 2016

Abstract5‐Trimethylsilyl substituted di‐ and trichloropyrimidines react with aryl‐ and alkyl amines to give regioselectively 2‐aminopyrimidines.
ChemInform Abstract: Visible‐Light Photoredox Synthesis of Chiral α‐Selenoamino Acids.
Authors: Jiang Min , Yang Haijun , Fu Hua 
Published: August 2016

AbstractA simple and scalable β‐carbon coupling of N‐acetoxyphthalimide derivatives of L‐aspartic as well as L‐glutamic acid with diaryl or dialkyl diselenides is described.
Development of Potent and Metabolically Stable APJ Ligands with High Therapeutic Potential
Authors: Juhl Cathleen , Els‐Heindl Sylvia , Schönauer Ria , Redlich Gorden , Haaf Erik , Wunder Frank , Riedl Bernd , Burkhardt Nils , Beck‐Sickinger Annette G. , Bierer Donald 
Published: August 2016

AbstractThe apelin ligand receptor system is an important target to develop treatment strategies for cardiovascular diseases. Although apelin exhibits strong inotropic effects, its pharmaceutical application is limited because no agonist with suitable properties is available. On the one hand, peptide ligands are too instable, and on the other hand, small‐molecule agonists show only low potency. This study describes the development of apelin (APJ) receptor agonists with not only high activity but also metabolic stability. Several strategies including capping of termini, insertion of unnatural amino acids, cyclization, and lipidation were analyzed. Peptide activity was tested using a Ca2+‐mobilization assay and the degradation of selected analogues was analyzed in rat plasma. The best results were obtained by N‐terminal lipidation of a 13‐mer apelin derivative. This analogue displayed a half‐life of 29 h in rat plasma, compared with 0.025 h for the wild‐type peptide. Furthermore, in vivo pharmacokinetics revealed a clearance of 0.049 L h−1 kg−1 and a half‐life of 0.36 h. In summary, amino acid substitution and fatty acid modification resulted in a potent and 1000‐fold more stable peptide that exhibits high pharmaceutical potential.
Catalytic Oxygen Evolution from Manganese Complexes with an Oxidation‐Resistant N,N,O‐Donor Ligand
Authors: Michaelos Thoe K. , Lant Hannah M. C. , Sharninghausen Liam S. , Craig Stephanie M. , Menges Fabian S. , Mercado Brandon Q. , Brudvig Gary W. , Crabtree Robert H. 
Published: August 2016

AbstractThere is great interest in developing Mn water‐splitting catalysts due to their low cost, abundance, and relevance to the oxygen‐evolving complex (OEC). Three ligands with highly donating pyridine alkoxide moieties, including 2‐(pyridin‐2‐yl)propan‐2‐ol (pyalkH), 2,2′‐(pyridine‐2,6‐diyl)bis(propan‐2‐ol) (py‐dialkH2), and 2‐[(2,2′‐bipyridin)‐6‐yl]propan‐2‐ol (bipy‐alkH), have been screened with Mn for oxygen‐evolution catalysis. Complexes with the ligand bipy‐alkH were shown to evolve O2 when driven by Oxone (potassium peroxymonosulfate). The catalytic mixture generated from the precursor complex [Mn(bipy‐alkH)Cl2] retained activity in unbuffered solution beyond 160 h.
From Barley Straw to Valuable Polyols: A Sustainable Process Using Ethanol/Water Mixtures and Hydrogenolysis over Ruthenium‐Tungsten Catalyst
Authors: Fabičovicová Katarína , Lucas Martin , Claus Peter 
Published: August 2016

AbstractOrganosolv fractionation of barley straw followed by a hydrogenolysis reaction of the resulting organosolv pulp over a heterogeneous catalyst containing ruthenium and tungsten on activated carbon (Ru‐W/AC) is a potential pathway to produce valuable chemicals from lignocellulose‐based feedstock in a future biorefinery. Polyols, such as ethylene glycol, propylene glycol, or 1,2‐butanediol, can be obtained with a very high yield of 70 % using organosolv barley pulp pretreated in a 50:50 wt % ethanol/water solution at 200 °C and a processing time of one hour. Moreover, we investigated the influence of several pretreatment parameters (e.g., solvent/water ratio, reaction temperature, and reaction time) on the pulp composition and product distribution obtained during the hydrogenolysis reaction to reduce the production of undesired side molecules. Finally, the optimal organosolv pretreatment conditions for straw were successfully transferred to other lignocellulose‐based feedstock, namely bamboo foliage and hemp shives.
Climatic controls on the isotopic composition and availability of soil nitrogen across mountainous tropical forest
Authors: Weintraub Samantha R. , Cole Rebecca J. , Schmitt Carl G. , All John D. 
Published: August 2016

AbstractWhile tropical forests play a critical role in global carbon (C) and nitrogen (N) cycles, how their biogeochemical dynamics will respond to changes in climate, especially warming, is uncertain. To shed light on links between climate and N cycling in tropical forests, we measured bulk surface soil C and N concentrations and isotopic content at 40 forested sites spanning an 1800 m elevation transect in Central America, possessing wide variation in mean annual temperature (MAT; range = 10°C) and precipitation (MAP; range = 1.2 m). Climate and terrain attributes were extracted from gridded data sets and regressed against soil variables, and then, empirical relationships were combined with a mass balance model to scale up to the larger landscape. Across the remote study region, elevation and soil δ15N values displayed a strong negative relationship, while elevation was positively related to percent of soil C, N, and C:N ratios. As elevation was tightly correlated with MAT and MAP, soil chemical and isotopic content varied strongly with climate. For example, for every degree increase in MAT, soil δ15N values—an indicator of relative gaseous N losses—increased by a factor of 0.4, and soil C:N ratios, which affect net N mineralization and N availability, declined by a factor of 1.1. With the 40 sites binned into bioclimatic life zones, montane, premontane, and wet‐premontane transition forests showed distinct clustering of soil chemical and isotopic properties, yet forest type alone explained less variation compared to continuous elevation–climate parameters. Results of the spatially applied 15N mass balance model implied shifts in the contribution of gaseous‐to‐total N loss, from 10% or less in cool, wet high‐elevation forests to upwards of 60% at warmer, drier, low‐elevation sites. Climate variation was thus associated with significant shifts in N dynamics across this montane tropical region, yet more work is needed to decouple direct vs. indirect climatic controls. While the mechanisms deserve further study, observed shifts in indicators of N availability and gaseous loss may be useful in managing and modeling tropical forests under climate change.
New Contact Probe and Method to Measure Electrical Resistances in Battery Electrodes
Authors: Mainusch Nils , Christ Torge , Siedenburg Thammo , O'Donnell Tom , Lutansieto Meylia , Brand Peter‐Jochen , Papenburg Gerhard , Harms Nina , Temel Bilal , Garnweitner Georg , Viöl Wolfgang 
Published: August 2016

AbstractElectrical resistivity is an important measure to qualify electrodes for lithium‐ion batteries. A reliable determination of conductivity is of high practical importance with regard to, for example, electrode production improvements and quality control. To complement state‐of‐the‐art measuring techniques, a new method has been developed based on a new “micron‐powder probe”. Following a simple measuring procedure, the system allows nondestructive, highly reproducible, and rapid data acquisition. In this paper, we describe the new concept thoroughly and present experimental results. These results demonstrate that an initial determination of resistance values in battery electrodes is beneficial especially if it is combined with an electrical postmortem analysis of cycled cathode disks. The outcome of our investigation is validated with regard to the electrochemical performance of cathodes in half‐cells.
Development, Status, and Prospects of Coal Tar Hydrogenation Technology
Authors: Yuan Yang , Li Dong , Zhang Linna , Zhu Yonghong , Wang Lei , Li Wenhong 
Published: August 2016

AbstractChina is rich in coal resources, and the production of mid‐to‐low‐temperature coal tar is increasing gradually. Due to containing more aliphatic hydrocarbons and less aromatic hydrocarbons, mid‐to‐low‐temperature coal tar is suitable for hydrogenation to produce fuel oil. Domestic mid‐to‐low‐temperature coal tar hydrogenation technologies are investigated here. All the technologies are divided into 6 steps, that is, coal tar hydrogenation technology of the light fraction, the delayed coking tar, the suspending‐bed reactor, the full‐range, the extractive wide distillate, and the boiling‐bed reactor. Focused on the technical features with a detailed analysis and comparison of different hydrogenation technologies, the main problems in the development of coal tar hydrogenation are described. The developments in process technology, coal tar refinement, and deep processing products will heavily influece the direction of coal tar hydrogenation in the future.
A Crystalline/Amorphous Cobalt(II,III) Oxide Hybrid Electrocatalyst for Lithium–Air Batteries
Authors: Khajehbashi S. Mohammad B. , Li Jiantao , Wang Manman , Xu Lin , Zhao Kangning , Wei Qiulong , Shi Changwei , Tang Chunjuan , Huang Lei , Wang Zhaoyang , Mai Liqiang 
Published: August 2016

AbstractWeakening of the oxygen bond is the main intention in the design and synthesis of catalysts for the oxygen reduction reaction (ORR). Hybrid‐structured electrocatalysts are promising candidates for this purpose; however, the use of noble metals and the combination of different materials, such as graphene and metal oxides, usually limits their synthesis on the laboratory scale. Herein, we introduce an oxidation and rapid‐cooling process as a novel and facile way to synthesize a bare Co3O4 hybrid crystalline/amorphous catalyst. Characterization of this material shows that the facile synthesis process is effective in forming an amorphous layer on the crystal structure of Co3O4. The cyclic voltammetry and rotating disc electrode results in aqueous solution prove the good performance of the catalyst. A Li–air battery with this catalyst successfully sustains about 2500 h of continuous cycling (120 cycles) with an average discharge voltage of 2.80 V and a limited specific capacity of 1000 mAh g−1, which proves the high performance of this catalyst in non‐aqueous electrolyte. We show that the origin of the high catalytic performance in this hybrid structure derives from the synergistic behavior of two different active sites, and this concept facilitates the design and synthesis of electrocatalysts by rapid‐cooling synthesis for the industrial scale.
Unusual Course of Lafora Disease
Authors: Zutt Rodi , Drost Gea , Vos Yvonne J. , Elting Jan Willem , Miedema Irene , Tijssen Marina A. J. , Brouwer Oebele F. , de Jong Bauke M. 
Published: August 2016

SummaryA 42‐year‐old male was admitted for refractory status epilepticus. At the age of 25, he had been diagnosed with juvenile myoclonic epilepsy. He had a stable clinical course for over a decade until a recent deterioration of behavior and epilepsy. After exclusion of acquired disorders, diagnostic work‐up included application of next‐generation sequencing (NGS), with a gene panel targeting progressive myoclonic epilepsies. This resulted in the diagnosis Lafora disease resulting from compound heterozygous NHLRC1 pathogenic variants. Although these pathogenic variants may be associated with a variable phenotype, including both severe and mild clinical course, the clinical presentation of our patient at this age is very unusual for Lafora disease. Our case expands the phenotype spectrum of Lafora disease resulting from pathogenic NHLRC1 variants and illustrates the value of using NGS in clinical practice to lead to a rapid diagnosis and guide therapeutic options.
Mono‐block and non‐matching multi‐block structured mesh adaptation based on aerodynamic functional total derivatives for RANS flow
Authors: Resmini A. , Peter J. , Lucor D. 
Published: August 2016

SummaryAn enhanced goal‐oriented mesh adaptation method is presented based on aerodynamic functional total derivatives with respect to mesh nodes in a Reynolds‐Averaged Navier‐Stokes (RANS) finite‐volume mono‐block and non‐matching multi‐block‐structured grid framework. This method falls under the category of methods involving the adjoint vector of the function of interest. The contribution of a Spalart–Allmaras turbulence model is taken into account through its linearization. Meshes are adapted accordingly to the proposed indicator. Applications to 2D RANS flow about a RAE2822 airfoil in transonic, and detached subsonic conditions are presented for the drag coefficient estimation. The asset of the proposed method is patent. The obtained 2D anisotropic mono‐block mesh well captures flow features as well as global aerodynamic functionals. Interestingly, the constraints imposed by structured grids may be relaxed by the use of non‐matching multi‐block approach that limits the outward propagation of local mesh refinement through all of the computational domain. The proposed method also leads to accurate results for these multi‐block meshes but at a fraction of the cost. Finally, the method is also successfully applied to a more complex geometry, namely, a mono‐block mesh in a 3D RANS transonic flow about an M6 wing. Copyright © 2016 John Wiley & Sons, Ltd.
Language learning from inconsistent input: Bilingual and monolingual toddlers compared
Authors: de Bree Elise , Verhagen Josje , Kerkhoff Annemarie , Doedens Willemijn , Unsworth Sharon 
Published: August 2016

AbstractThis study examines novel language learning from inconsistent input in monolingual and bilingual toddlers. We predicted an advantage for the bilingual toddlers on the basis of the structural sensitivity hypothesis. Monolingual and bilingual 24‐month‐olds performed two novel language learning experiments. The first contained consistent input, and the second occasionally contained inconsistent input (i.e., “errors”). Neither group showed learning of the novel pattern in the consistent experiment. The bilingual toddlers, but not the monolinguals, showed learning in the inconsistent experiment, which suggests they are better at detecting regularities from inconsistent input than monolinguals.Highlights

Language learning experiments consider consistent input, whereas inconsistent input is likely to occur in real life.
Monolingual and bilingual toddlers' performance on a language learning task of non‐adjacent dependencies was assessed, using inconsistent input.
The group of bilingual toddlers was able to find the language pattern despite the inconsistencies, whereas the group of monolingual toddlers was not.
Capillary Imbibition of Gadolinium Halides into WS2 Nanotubes: a Molecular Dynamics View
Authors: Deepak Francis Leonard , Enyashin Andrey N. 
Published: August 2016

AbstractThe structure of the molten salts GdX3, where X denotes Cl, Br, or I, and the kinetics of their penetration into WS2 nanotubes were investigated using molecular dynamics simulations. The GdCl3 and GdBr3 melts are found to comprise an amorphous framework structure with substantial intermediate‐range ordering, as manifested by pair distribution, and angle‐resolved pair‐pair distribution functions associated with cationic correlations. In contrast, the GdI3 melt is a liquid with short‐range cationic ordering. These structural peculiarities cause dramatically different mobility of Gd cations among pure GdX3 melts and explain the relative difference in the capillary activity of WS2 nanotubes regarding the melts, as observed in preliminary experiments. Extended MD simulations of GdCl3 dissolved in molten KCl predict the total degradation of the GdCl3 framework structure below 40 mol %, although no essential uptake of Gd cations by the WS2 nanotube is observed, due to more progressive diffusion of K cations. Our theory suggests that, among the considered halides, only the GdI3 compound is suitable for Gd encapsulation into WS2 nanotubes employing the capillary technique.
Enantioselective Gas Chromatography with Derivatized Cyclodextrins in the Flavour and Fragrance Field
Authors: Cagliero Cecilia , Sgorbini Barbara , Cordero Chiara , Liberto Erica , Rubiolo Patrizia , Bicchi Carlo 
Published: August 2016

AbstractThis article deals with enantioselective gas chromatography (Es‐GC) utilizing cyclodextrin derivatives as chiral stationary phases (CSPs) for chiral recognition in the flavour and fragrance field. It consists of two main parts. The first one concerns cyclodextrins and their use in Es‐GC, and it deals with their introduction and evolution as CSPs in GC, together with some theoretical aspects involved with enantiomeric separation and their consequent influence on routine chiral recognition. The second part reports on the strategy of chiral recognition in routine analysis with cyclodextrin derivatives as CSP, illustrated with examples from the authors’ everyday experiences. This part describes how to identify enantiomers or to measure their excess or ratio determination in complex mixtures; in particular, it discusses the opportunities offered by multidimensional and fast GC techniques, the role of mass spectrometry, and the application of total analysis systems to chiral recognition.