bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regio‐ and Stereoselective Synthesis of Dithiocarbonates under Ambient and Solvent‐Free Conditions
Authors: Diebler Johannes , Spannenberg Anke , Werner Thomas 
Published: May 2016

AbstractHerein, we report on the utilization of readily available lithium tert‐butoxide as an efficient catalyst for the addition of carbon disulfide to terminal and internal epoxides under ambient conditions. Notably, the reaction proceeds regio‐ and stereoselectively. By applying the optimized conditions, 14 terminal and internal epoxides were converted. The desired cyclic dithiocarbonates were isolated in yields up to 95 % after simple filtration over silica. NMR spectroscopy experiments to identify the mode of activation were performed, and they indicated activation of carbon disulfide by the catalyst. The reaction of cis‐2,3‐butyleneoxide gave only the trans‐dithiocarbonate, whereas the conversion of (R)‐propylen oxide gave the respective thiocarbonate stereoselectively as one enantiomer (>99 % ee) in 87 % yield.
The Origin of Anti‐Markovnikov Regioselectivity in Alkene Hydroamination Reactions Catalyzed by [Rh(DPEphos)]+
Authors: Couce‐Rios Almudena , Lledós Agustí , Ujaque Gregori 
Published: May 2016

AbstractThe development of regioselective anti‐Markovnikov alkene's hydroamination is a long‐standing goal in catalysis. The [Rh(COD)(DPEphos)]+ complex is the most general and regioselective group 9 catalyst for such a process. The reaction mechanism for intermolecular hydroamination of alkenes catalyzed by [Rh(DPEphos)]+ complex is analyzed by means of DFT calculations. Hydroamination (alkene vs. amine activation routes) as well as oxidative amination pathways are analyzed. According to the computational results the operating mechanism can be generally described by alkene coordination, amine nucleophilic addition, proton transfer through the metal center and reductive elimination steps. The mechanism for the formation of the oxidative amination side product goes via a β‐elimination after the nucleophilic addition and metal center protonation steps. The origin of the regioselectivity for the addition process (Markovnikov vs. anti‐Markovnikov additions) is shown to be not charge but orbitally driven. Remarkably, η2 to η1 slippage degree on the alkene coordination mode is directly related to the regioselective outcome.
Reaction Mechanism of Mycobacterium Tuberculosis Glutamine Synthetase Using Quantum Mechanics/Molecular Mechanics Calculations
Authors: Moreira Cátia , Ramos Maria J. , Fernandes Pedro Alexandrino 
Published: May 2016

AbstractThis paper is devoted to the understanding of the reaction mechanism of mycobacterium tuberculosis glutamine synthetase (mtGS) with atomic detail, using computational quantum mechanics/molecular mechanics (QM/MM) methods at the ONIOM M06‐D3/6‐311++G(2d,2p):ff99SB//B3LYP/6‐31G(d):ff99SB level of theory. The complete reaction undergoes a three‐step mechanism: the spontaneous transfer of phosphate from ATP to glutamate upon ammonium binding (ammonium quickly loses a proton to Asp54), the attack of ammonia on phosphorylated glutamate (yielding protonated glutamine), and the deprotonation of glutamine by the leaving phosphate. This exothermic reaction has an activation free energy of 21.5 kcal mol−1, which is consistent with that described for Escherichia coli glutamine synthetase (15–17 kcal mol−1). The participating active site residues have been identified and their role and energy contributions clarified. This study provides an insightful atomic description of the biosynthetic reaction that takes place in this enzyme, opening doors for more accurate studies for developing new anti‐tuberculosis therapies.
Computational Design of Iron Diphosphine Complexes with Pendant Amines for Hydrogenation of CO2 to Methanol: A Mimic of [NiFe] Hydrogenase
Authors: Chen Xiangyang , Jing Yuanyuan , Yang Xinzheng 
Published: May 2016

AbstractInspired by the active‐site structure of the [NiFe] hydrogenase, we have computationally designed the iron complex [PtBu2NtBu2)Fe(CN)2CO] by using an experimentally ready‐made diphosphine ligand with pendant amines for the hydrogenation of CO2 to methanol. Density functional theory calculations indicate that the rate‐determining step in the whole catalytic reaction is the direct hydride transfer from the Fe center to the carbon atom in the formic acid with a total free energy barrier of 28.4 kcal mol−1 in aqueous solution. Such a barrier indicates that the designed iron complex is a promising low‐cost catalyst for the formation of methanol from CO2 and H2 under mild conditions. The key role of the diphosphine ligand with pendent amine groups in the reaction is the assistance of the cleavage of H2 by forming a Fe−Hδ−⋅⋅⋅Hδ+−N dihydrogen bond in a fashion of frustrated Lewis pairs.
α,β‐Double Electrophilic Addition of Allene‐1,3‐Dicarboxylic Esters for the Construction of Polysubstituted Furans by KI/tert‐Butyl Hydroperoxide (TBHP)‐Promoted Oxidative Annulation
Authors: Li Hong‐Liang , Wang Yu , Sun Pei‐Pei , Luo Xiaoyan , Shen Zhenlu , Deng Wei‐Ping 
Published: May 2016

AbstractAn unprecedented KI/tert‐butyl hydroperoxide promoted tandem Michael addition/oxidative annulation of allene‐1,3‐dicarboxylic esters and 1,3‐dicarbonyl compounds has been developed. This procedure provides a new, facile, and transition‐metal‐free synthetic approach to afford polysubstituted furans in moderate to excellent yields (up to 93 %). This method first establishes a α,β‐double electrophilic reaction mode of allene‐1,3‐dicarboxylic esters to form 1,3‐dicarbonyl compounds.
Mechanism and Selectivity of RuII‐ and RhIII‐Catalyzed Oxidative Spiroannulation of Naphthols and Phenols with Alkynes through a C−H Activation/Dearomatization Strategy
Authors: Zhang Mei , Huang Genping 
Published: May 2016

AbstractThe ruthenium‐ and rhodium‐catalyzed oxidative spiroannulation of naphthols and phenols with alkynes was investigated by means of density functional theory calculations. The results show that the reaction undergoes O−H deprotonation/C(sp2)−H bond cleavage through a concerted metalation–deprotonation mechanism/migratory insertion of the alkyne into the M−C bond to deliver the eight‐membered metallacycle. However, the dearomatization through the originally proposed enol–keto tautomerization/C−C reductive elimination was calculated to be kinetically inaccessible. Alternatively, an unusual metallacyclopropene, generated from the isomerization of the eight‐membered metallacycle through rotation of the C−C double bond, was identified as a key intermediate to account for the experimental results. The subsequent C−C coupling between the carbene carbon atom and the carbon atom of the 2‐naphthol/phenol ring was calculated to be relatively facile, leading to the formation of the unexpected dearomatized products. The calculations reproduce quite well the experimentally observed formal [5+2] cycloaddition in the rhodium‐catalyzed oxidative annulation of 2‐vinylphenols with alkynes. The calculations show that compared with the case of 2‐alkenylphenols, the presence of conjugation effects and less steric repulsion between the phenol ring and the vinyl moiety make the competing reductive oxyl migration become dominant, which enables the selectivity switch from the spiroannulation to the formal [5+2] cycloaddition.
ChemInform Abstract: Anomalous X‐Ray Scattering Study of the Quasi‐Crystalline Al65Cu20Fe15 Alloy
Authors: MATSUBARA E. , WASEDA Y. , TSAI A. P. , INOUE A. , MASUMOTO T. 
Published: May 2016

Abstractindicates that a strong directional dependence along the symmetrical axes exist for the Cu atoms but not for the Fe atoms.
ChemInform Abstract: Characterization of β‐Silicon Nitride Whiskers
Authors: HOMENY J. , NEERGAARD L. J. , KARASEK K. R. , DONNER J. T. , BRADLEY S. A. 
Published: May 2016

Abstract(commercially available β‐Si3N4) is performed by XRD, XPS, SEM, TEM, BET measurements and chemical analysis.
ChemInform Abstract: Structures of the Copper Vanadium Bronzes CuxV12O29 with x = 1.2, 1.5, and 1.9.
Authors: KATO K. , TAKAYAMA‐MUROMACHI E. , KANKE Y. 
Published: May 2016

AbstractThe three title compounds all crystallize in the monoclinic space group C2/m with Z=2.
ChemInform Abstract: The Structure of the Copper Vanadium Bronze Cu0.261V2O5. ‐ A Refinement.
Authors: KATO K. , TAKAYAMA‐MUROMACHI E. , KANKE Y. 
Published: May 2016

AbstractSingle crystals of the title compound are grown from the melt using the Bridgman method (oxidation of Cu1.2V12O29).
ChemInform Abstract: The Improved Passivation of Iron Induced by Additions of Tungsten.
Authors: CHEN J. , WU J. K. 
Published: May 2016

AbstractThe corrosion behavior in 1 N H2SO4 is studied for pure iron, iron alloyed with small amounts of tungsten, and iron passivated in 1 N H2SO4 solutions containing WO42‐.
ChemInform Abstract: Complexes with Phosphinomethane and Phosphinomethanide Ligands. Part 17. Lithium Phosphinomethanides: Two Novel Structures.
Authors: KARSCH H. H. , ZELLNER K. , MIKULCIK P. , LACHMANN J. , MUELLER G. + 
Published: May 2016

AbstractThe structure of the two Li phosphinomethanides (IV) (space group Pna21, Z=4) and (VI) (P21/c, Z=2) are determined by X‐ray analysis.
ChemInform Abstract: New Access to Acyl‐ and Aroyllithiums via Lithium‐Tellurium Exchange.
Authors: HIIRO T. , MORITA Y. , INOUE T. , KAMBE N. , OGAWA A. , RYU I. , SONODA N. 
Published: May 2016

AbstractEfficient Li‐Te exchange reactions generate acyllithiums such as (III) which react with electrophiles, e.g. (II) or (VI) to provide ketones such as (IV) or (VII).
ChemInform Abstract: Reactions of 4‐Methyl‐1‐(1′‐methylethyl)‐4‐nitrocyclohexa‐2,5‐dien‐1‐yl Acetates with Nitrogen Dioxide; Towards a Mechanism for the Formation of Polynitro Cyclohexenyl Esters on Reaction of p‐Cymene with Nitrogen Dioxide in Acetic Anhydride.
Authors: ABELL A. D. , HARTSHORN M. P. , ROBINSON W. T. , WALLER A. G. , WRIGHT G. J. 
Published: May 2016

AbstractThe reaction of p‐cymene (IV) with NO2 (already studied in Ac2O, 24 h) is further examined in great detail using CH2Cl2 as well as Ac2O (with shortened reaction time) as solvents.
ChemInform Abstract: Reductive Coupling by Chromium(0) ‐ (Bibenzyl)‐ and (Stilbene)tricarbonylchromium(0) Complexes by a One‐Pot Reaction from Benzylic Halides.
Authors: WEY H. G. , BUTENSCHOEN H. + 
Published: May 2016

AbstractReaction of benzylic mono‐ and dihalides such as (I) or (III) with Cr(CO)3(NH3)3 leads to diarylethanes and ‐ethenes such as (II) or (IV) in satisfactory yields.
ChemInform Abstract: Synthesis of Isopropyl and tert‐Butyl Pyridyl Ketones by Alkylation of Acetylpyridines with Methyl Iodide Using Phase‐Transfer Catalysis.
Authors: RUBINA K. , GOLDBERG YU. , SHYMANSKA M. 
Published: May 2016

AbstractThe methyl pyridyl ketones (I) are treated with excess methyl iodide (II) and potassium hydroxide in the presence of a crown ether to produce the isopropyl ketones (III).
ChemInform Abstract: Facile Acylation of Alcohols Using Esters and Silica Gel Supported Metallic Sulfates and Hydrogen Sulfates.
Authors: NISHIGUCHI T. , TAYA H. 
Published: May 2016

AbstractAlcohols such as (I) are acylated in a quite simple operation in high yields by being heated in esters such as (II) in the presence of silica gel supported metallic sulfates and hydrogen sulfates, such as Ce(SO4)2, Ti(SO4)2, Fe2(SO4)3, and NaHSO4.
ChemInform Abstract: Synthesis of Fluorinated α‐Amino Ketones. Part 3. Preparation of Fluorinated Ketone Analogues of Phenylalanine, Lysine, and p‐(Guanidino)phenylalanine.
Authors: KOLB M. , NEISES B. , GERHART F. 
Published: May 2016

AbstractThe synthesis of the title ketones (IV) using a one‐pot sequence related to the Dakin‐West reaction starts from the respective acylated amino acids (I) proceeding via oxazolone derivatives (II).
ChemInform Abstract: Antifungal Agents. Part 27. Novel 5‐(((Substituted phenyl)thio)methyl)isoxazolidines.
Authors: DECORY T. R. , MULLEN G. B. , MITCHELL J. T. , ALLEN S. D. , GEORGIEV V. ST. 
Published: May 2016

AbstractTwelve title compounds of type (III) which are synthesized via 1,3‐dipolar cycloaddition are screened for in vitro antifungal activity.
ChemInform Abstract: A Short Synthesis of Fusaric Acid and Analogues.
Authors: WALDNER A. 
Published: May 2016

AbstractCycloaddition reaction of the α,β‐unsaturated hydrazones (I) with α‐chloroacrylonitrile (II) in the presence of triethylamine is accompanied by elimination of HCl, producing the unstable 1‐amino‐2‐cyano‐1,4‐dihydropyridines (III).
ChemInform Abstract: Structural Studies on Cyclopentadienyl Compounds of Trivalent Cerium: Tetrameric (MeC5H4)3Ce and Monomeric (Me3SiC5H4)3Ce and ((Me3Si)2C5H3)3Ce and Their Coordination Chemistry.
Authors: STULTS S. D. , ANDERSEN R. A. , ZALKIN A. 
Published: May 2016

AbstractThe coordinated THF in (I) can also be removed by the toluene reflux method to give (II) in 73% yield.
ChemInform Abstract: Synthesis of Bio‐Relevant Functionalized Acids. Part 7. A New General Access to α‐Trifluoromethyl‐Substituted Aromatic and Heteroaromatic α‐Amino Acids.
Authors: BURGER K. , GAA K. , GEITH K. , SCHIERLINGER C. 
Published: May 2016

AbstractReaction of 2‐(hydroxymethyl)furan (Ia) and the corresponding thiophene (Ib) with 5‐fluoro‐4‐(trifluoromethyl)oxazole (II) and subsequent hydrolysis yield the hetaryl(trifluoromethyl)glycine derivatives (III).
ChemInform Abstract: Simple Three‐Step Synthesis of (R)‐ and (S)‐4‐Amino‐3‐hydroxybutanoic Acid (GABOB) by Stereoselective Aldol Addition.
Authors: BRAUN M. , WALDMUELLER D. + 
Published: May 2016

Abstract(R)‐ and (S)‐GABOB (V) are prepared by the aldol reaction of (R)‐ and (S)‐2‐hydroxy‐1,2,2‐triphenylethyl acetate (I) with the N‐protected glycinal (II), followed by hydrolysis and deprotection.
ChemInform Abstract: Spectroscopic Studies of N‐S‐O Anions: The Reactions of NSO‐ with Elemental Sulfur and with S4N4
Authors: CHIVERS T. , SCHMIDT K. J. , MCINTYRE D. D. , VOGEL H. J. 
Published: May 2016

Abstract(UV/VIS, IR, Raman, 14N, 17O and 33S NMR).
ChemInform Abstract: Mechanism of Dehydration of Zn0.5Mg0.5(H2PO4)2·2 H2O.
Authors: TROJAN M. , BRANDOVA D. 
Published: May 2016

AbstractThe condensation reactions proceeding during the calcination of the title phosphate are followed by TG, DTG, and DTA under non‐isothermal and quasi‐isothermal‐isobaric conditions.
ChemInform Abstract: A One‐Step Conversion of Certain Indole and Pyrrole Glyoxylic Acid Esters to the Corresponding Acetates.
Authors: DEMOPOULOS V. J. 
Published: May 2016

AbstractThe hetarylglyoxalates (I) are treated with sodium dihydrogen hypophosphite in the presence of palladium on carbon to produce the corresponding acetates (II) via hydrogen transfer reaction.
ChemInform Abstract: Nucleophilic Reactivity of Zinc and Copper Carbenoids. Part 2.
Authors: KNOCHEL P. , CHOU T.‐S. , CHEN H. G. , YEH M. C. P. , ROZEMA M. J. 
Published: May 2016

AbstractTreatment of iodomethyl pivalate (I) with activated zinc foil (II) produces the zinc reagent (III) which undergoes transmetalation with the copper cyanide (IV) to give a solution of the mixed cuprate reagent (V).
ChemInform Abstract: Photochemical Chlorodecarboxylation via an Electron Transfer Mechanism.
Authors: OKADA K. , OKAMOTO K. , ODA M. 
Published: May 2016

AbstractPhotolysis of the N‐acyloxyphthalimides (I) in tetrachloromethane and in the presence of 1,4‐diazabicyclo(2.2.2)octane (DABCO) results in cleavage and chlorination to produce the chlorides (II).
ChemInform Abstract: Synthesis of β,β′‐Difluorinated Ethers.
Authors: CHAABOUNI M. M. , BAKLOUTI A. 
Published: May 2016

AbstractThe sodium alkoxides derived from the β‐fluoro alcohols (I) are coupled with 2‐fluoroethyl tosylate (II) to produce the β,β'‐difluoro ethers (III).
ChemInform Abstract: Catalytic Formation of an Amide Hydroperoxide and Hydrogen Peroxide Using Rhodium Complexes and Dioxygen/Dihydrogen Mixtures.
Authors: GAMAGE S. N. , JAMES B. R. 
Published: May 2016

AbstractTreatment of N,N‐dimethylacetamide (I) with oxygen and hydrogen in the presence of a rhodium(III) catalyst results in the formation of the hydroperoxide (II), the formamide (III), and hydrogen peroxide (IV).
ChemInform Abstract: A Simple and Inexpensive Synthesis of a Useful Carbamate.
Authors: DEPREUX P. , BETHEGNIES G. , MARCINCAL A. 
Published: May 2016

Abstract3‐Butoxy‐2‐carbamoyloxy‐1‐chloropropane (V) is an important therapeutic carbamate, which is usually prepared by consecutive treatment of the alcohol (III) with phosgene (VI) in the presence of antipyrine and aqueous ammonia (VII).
ChemInform Abstract: The Pagodane Route to Dodecahedranes: Dodecahedradienes ‐ Unusually “Pyramidalized”, Isolable Olefins.
Authors: MELDER J.‐P. , PINKOS R. , FRITZ H. , PRINZBACH H. 
Published: May 2016

AbstractThe title compounds (III) and (V) (no yield given) are thermally stable but extremely sensitive to oxygen.
ChemInform Abstract: Annulation Reactions of 4‐Methoxy‐2‐pyrone with Various Active Methyl Compounds.
Authors: TANYELI C. , TARHAN O. 
Published: May 2016

AbstractThe pyrone (I) mentioned in the title is cleaved and coupled with the anions derived from ethyl acetoacetate (II), ethyl acetate (IVa), acetonitrile (IVb), dimethyl sulfoxide (IVc), and dimethyl methylphosphonate (IVd).
ChemInform Abstract: Synthetic Studies on O‐Heterocycles via a Cycloadditions. Part 1. Photochemical (Electron Transfer Sensitized) C‐C Cleavage of Diaryloxiranes.
Authors: CLAWSON P. , LUNN P. M. , WHITING D. A. 
Published: May 2016

AbstractIrradiation of trans‐stilbene oxide (II) with naphthalene‐1,4‐dicarbonitrile (NDC) as a sensitizer in the presence of electron deficient dipolarophiles such as (I), (IV), or (VI) leads, via presumed carbon carbonyl ylide, to various tetrahydro and dihydro‐furans.
ChemInform Abstract: N‐Iodosuccinimide‐Mediated Oxidative Cyclization of Mono‐tert‐butyldimethylsilylated Diols.
Authors: MCDONALD C. E. , BEEBE T. R. , BEARD M. , MCMILLEN D. , SELSKI D. 
Published: May 2016

AbstractThe mono‐O‐silylated 1,4‐diols (I), (IV), (VI), and (VIII) are oxidatively cyclized with N‐iodosuccinimide, yielding the siloxyfuran derivatives (II), (III), (V), (VII), and (IX).
ChemInform Abstract: Regioselective Synthesis of 2‐ and 3‐Acylpyrroles by Reaction of β‐Amino Enones with α‐Amino Ketone Hydrochlorides.
Authors: ALBEROLA A. , ANDRES J. M. , GONZALEZ A. , PEDROSA R. , VICENTE M. 
Published: May 2016

AbstractThe β‐amino enones (I) undergo cyclization with the α‐amino ketone hydrochlorides (II) in methanol to give the 2‐acylpyrroles (III) and/or the 3‐acylpyrroles (IV).
ChemInform Abstract: Methanol‐Incorporated Photoaddition of N‐Methyl‐9,10‐phenanthrenedicarboximide to Alkenes. Addition at Carbonyl and Phenanthrene‐Ring Carbon Atoms.
Authors: KUBO Y. , NANBA M. , HAYASHI E. , ARAKI T. 
Published: May 2016

AbstractWhereas irradiation of a MeCN‐MeOH solution of the title compound (I) with alkenes (II) affords the same product types (III) + (IV) previously obtained by similar photoreactions in benzene, irradiation in the presence of the alkenes (V), (IX), or (XII) gives mainly methanol‐incorporated adducts.
ChemInform Abstract: Heterocyclic 1,4‐Naphthoquinone Derivatives. Part 1. Reaction of 2‐Chloro‐3‐chloroacetylamino‐1,4‐naphthoquinone with Aniline.
Authors: KALLMAYER H.‐J. , BINGER M. 
Published: May 2016

AbstractThe chloronaphthoquinone (III), prepared by coupling the aminochloronaphthoquinone (I) with the chloroacetyl chloride (II), reacts with two equivalents of aniline (IV) to give the corresponding anilino derivative (V).
ChemInform Abstract: Syntheses of the (4 + 2)Adducts of 2‐Pyrone‐5‐carboxylates with Substituted Ethylenes and Their Benzene Derivatives.
Authors: SHIMO T. , MURAOKA F. , SOMEKAWA K. 
Published: May 2016

AbstractDiels‐Alder reaction of the pyronecarboxylates (I) with the vinyl ethers (II) gives the endo‐ (III) and exo‐adducts (IV).
ChemInform Abstract: Potential Antimalarials. Part 8. Mono‐ and Di‐Mannich Bases of 2‐(7′‐Trifluoromethylquinolin‐4′‐ylamino)phenol via 2‐Nitrophenols.
Authors: BARLIN G. B. , YAN J.‐H. 
Published: May 2016

AbstractA series of di‐Mannich bases of type (V) are prepared using several sec. amines such as (III), pyrrolidine, and morpholine.
ChemInform Abstract: Studies on Antibacterial Agents. Part 1. Synthesis of Substitued 6,7‐Dihydro‐1‐oxo‐1H,5H‐benzo(i,j)quinolizine‐2‐carboxylic Acids.
Authors: ISHIKAWA H. , TABUSA F. , MIYAMOTO H. , KANO M. , UEDA H. , TAMAOKA H. , NAKAGAWA K. 
Published: May 2016

AbstractThe title compounds (X) are synthesized as shown in the reaction scheme, and tested for antibacterial activity.
ChemInform Abstract: Serial Radical Cyclization of Branched Carbohydrates. Part 2. Claisen Rearrangement Routes to Multiply‐Substituted Pyranoside Diquinanes.
Authors: PAK H. , DICKSON J. K. JUN. , FRASER‐REID B. 
Published: May 2016

AbstractStarting with the α‐D‐mannopyranoside (I), derivatives of the type (II) are prepared in several steps.
ChemInform Abstract: The Stereochemistry of the Reaction of α‐Silyl Lithium Reagents with Cyclic tert‐Butyldimethylsilyl Acyloins.
Authors: PRIETO J. A. , LARSON G. L. , GONZALEZ P. 
Published: May 2016

AbstractThe α‐siloxycycloalkanones (I) are olefinated with the lithium salts, derived from benzyltrimethylsilane (II), trimethylsilylacetonitrile (IV), or phenyl trimethylsilylmethyl sulfide (VI), to yield the α‐siloxy(methylene)cycloalkanes (III), (V), or (VII).
ChemInform Abstract: Reaction of Dialkyl Alkynylphosphonites with the Nitrile and Esters of Benzoylformic Acid.
Authors: BURANGULOVA R. N. , TRISHIN YU. G. , KONOVALOVA I. V. , BURNAEVA L. A. , CHISTOKLETOV V. N. , PUDOVIK A. N. 
Published: May 2016

AbstractThe phosphonites (I) react with benzoyl cyanide (II) to give the 1,3,2‐dioxaphospholanes (III).
ChemInform Abstract: Reaction of Titanium Alkoxides with N,N,N′,N′′‐Tetrakis(trimethylsilyl)phosphenodiimidic Amide.
Authors: BRUSILOVETS A. I. , RUSANOV E. B. , KHOLODOVICH V. V. 
Published: May 2016

AbstractThe phosphenodiimidic amide (I) is coupled with the titanium alkoxides (II) to give the heterocyclic compounds (III).
ChemInform Abstract: Synthesis and X‐Ray Structure of Bis(trifluoromethyl)(N,N‐diethyldithiocarbamato)copper. A Remarkably Stable Perfluoroalkylcopper(III) Complex.
Authors: WILLERT‐PORADA M. A. , BURTON D. J. , BAENZIGER N. C. 
Published: May 2016

AbstractThe cuprate (I) reacts with the thiuram disulfide (II) in DMF to produce the copper(III) complex (III) which is also prepared by trifluoromethylation of the dibromide (IV) with trifluoromethylcadmium iodide (V).
ChemInform Abstract: Synthesis and Reactions of Nickel and Palladium Carbon‐Bound Enolate Complexes.
Authors: BURKHARDT E. R. , BERGMAN R. G. , HEATHCOCK C. H. 
Published: May 2016

AbstractNi and Pd C‐bound enolates of the type (III) are prepared by reactions of chloro‐ or bromo(cyclopentadienyl)triphenylphosphine‐Ni or ‐Pd with corresponding potassium or lithium enolates as demonstrated for the examples (IIIa) and (IIIb).
ChemInform Abstract: Modification of Steroids in the Androstane Series with Three‐Membered Heterocycles at 17‐C.
Authors: SOVA A. N. , SAL'NIKOVA S. I. , GELLA I. M. , ALIEV A. E. , KOSTYANOVSKII R. G. 
Published: May 2016

AbstractThe spiro(androstane‐17,2'‐oxirane) (III) is transformed into the 17α‐aminomethyl derivatives (V) and (VII) upon reaction with the amines (IV) or (VI).
ChemInform Abstract: The Synthesis and Reactivity of Cyclic Thiocarbonates Derived from Some Carbohydrate 1,2‐Diols.
Authors: PATRONI J. J. , STICK R. V. , TILBROOK D. M. G. , SKELTON B. W. , WHITE A. H. 
Published: May 2016

AbstractThiocarbonylation of diols such as (I) leads to the corresponding cyclic thiocarbonates (III) and (IV).
ChemInform Abstract: Regio‐ and Chemoselective Epimerization of cis‐3‐Amino‐β‐lactams to the trans‐Isomers: A New Synthesis of Aztreonam.
Authors: KAWABATA T. , ITOH K. , HIYAMA T. 
Published: May 2016

AbstractThe cis‐amino(tert‐butoxycarbonyl)‐β‐lactams (I) are (partly) epimerized upon treatment with trifluoroacetic anhydride, followed by reesterification with diazomethane (II), yielding the trans‐substituted analogues (III).