bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘There but for you go I’: Interpreting the signifying world of Lerner and Loewe’s Brigadoon
Authors: Quinn Arianne Johnson 
Published: April 2017

Abstract
In 1949, British theatre critic Phil Hanna hailed Lerner and Loewe’s newly imported Brigadoon as a ‘rule-breaking’ production, referring to the innovative elements such as the invisible chorus and the incorporation of traditional Scottish music and dance. This production, which was re-cast in London with Scottish dancers and only the three American leads, faced constant comparisons to the musical, dramatic and dance styles of Rodgers and Hammerstein’s wildly successful imported production of Oklahoma! (1947). This article will examine the imported London production of Brigadoon through the lens of its British reception in order to demonstrate the show’s impact in postwar Britain and explore the distinctive unity of Lerner and Loewe’s musical and dramatic language. Further, it will explore the ways in which the Scottish musical elements, or signifiers, found in Brigadoon allowed British audiences to interpret the work as being simultaneously ‘Scottish’ and as a greater reflection of a postwar British cultural identity.
Book Reviews
Authors: Patmore David , Garber Michael G. , Miller Ray 
Published: April 2017

Abstract
THE BUSINESS OF OPERA, ANASTASIA BELINA-JOHNSON AND DEREK B. SCOTT (2015) Farnham, Surrey, UK, and Burlington, Vermont, USA: Ashgate. 218 pp., ISBN 978 1472429452, h/bk, £60
IRVING BERLIN’S AMERICAN MUSICAL THEATER, JEFFREY MAGEE (2012) Oxford: Oxford University Press, 328 pp., Broadway Legacies Series, ISBN: 978 0 19 539 826 7, h/bk, $35.00
MARC BLITZSTEIN: HIS LIFE, HIS WORK, HIS WORLD, HOWARD POLLACK (2012) New York: Oxford University Press, 618 pp., ISBN: 9780199791590, h/bk, $39.95
A gender-focused review of the effect of message source attractiveness on persuasion: Implications for marketers and advertisers
Authors: Pornpitakpan Chanthika , Li Qiuling , Fu Siu Fong Isabel 
Published: April 2017

AbstractThis study reviews research regarding the effects of source physical attractiveness on persuasion with focus on the interplay with source gender and receiver gender. Most evidence indicates that attractive female sources tend to be more persuasive than unattractive ones in attitudinal and behavioral measures. The results for male sources are equivocal, with few studies reporting the liability of male source attractiveness. Recipients’ sex is a poor predictor of source attractiveness impact for both male and female sources. The study’s contribution synthesizes decades of research on source attractiveness to suggest future research ideas for academics in marketing, psychology, and communications and to give recommendations for marketers, advertisers, and other practitioners aiming to influence people’s attitudes.
Tokophobia (fear of childbirth): prevalence and risk factors
Authors: Demšar Karin , Svetina Matija , Verdenik Ivan , Tul Natasa , Blickstein Isaac , Globevnik Velikonja Vislava 
Published: April 2017

AbstractObjective:To identify the prevalence of and to determine the risk factors for developing a fear of childbirth (tokophobia).Methods:We evaluated 191 pregnant women during Parenting and Childbirth Classes. Participants were approached when attending Parenting and Childbirth Classes between June 2014 and September 2014 and were asked to complete several questionnaires related to depression (CES-D), anxiety (STAI X1 and X2), satisfaction with life (SWLS), delivery expectation/experience (W-DEQ), and specific fears.Results:Most (90%) of the responders were nulliparous. As many as 75% of the participants reported low to moderate tokophobia, whereas 25% exhibited high or very high fear of childbirth. Pathological fear occurred in 1.6% of the participants. The most significant was the fear of having an episiotomy followed by fear of having no control on the situation and fear of pain. An association exists between a preferred elective cesarean birth and tokophobia.Conclusions:The results draw attention to the need for early detection and treatment of fear of childbirth. The data may help identifying women at risk that require prenatal psychological intervention.
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission
Authors: Wang Lihua , Zhang Tong , Wang Lin , Cai Yongping , Zhong Xiuying , He Xiaoping , Hu Lan , Tian Shengya , Wu Mian , Hui Lijian , Zhang Huafeng , Gao Ping 
Published: April 2017

AbstractPluripotent stem cells are known to display distinct metabolic phenotypes than their somatic counterparts. While accumulating studies are focused on the roles of glucose and amino acid metabolism in facilitating pluripotency, little is known regarding the role of lipid metabolism in regulation of stem cell activities. Here, we show that fatty acid (FA) synthesis activation is critical for stem cell pluripotency. Our initial observations demonstrated enhanced lipogenesis in pluripotent cells and during cellular reprogramming. Further analysis indicated that de novo FA synthesis controls cellular reprogramming and embryonic stem cell pluripotency through mitochondrial fission. Mechanistically, we found that de novo FA synthesis regulated by the lipogenic enzyme ACC1 leads to the enhanced mitochondrial fission via (i) consumption of AcCoA which affects acetylation‐mediated FIS1 ubiquitin–proteasome degradation and (ii) generation of lipid products that drive the mitochondrial dynamic equilibrium toward fission. Moreover, we demonstrated that the effect of Acc1 on cellular reprogramming via mitochondrial fission also exists in human iPSC induction. In summary, our study reveals a critical involvement of the FA synthesis pathway in promoting ESC pluripotency and iPSC formation via regulating mitochondrial fission.
Molecular basis for Cdk1‐regulated timing of Mis18 complex assembly and CENP‐A deposition
Authors: Spiller Frances , Medina‐Pritchard Bethan , Abad Maria Alba , Wear Martin A , Molina Oscar , Earnshaw William C , Jeyaprakash A Arockia 
Published: April 2017

AbstractThe centromere, a chromosomal locus that acts as a microtubule attachment site, is epigenetically specified by the enrichment of CENP‐A nucleosomes. Centromere maintenance during the cell cycle requires HJURP‐mediated CENP‐A deposition, a process regulated by the Mis18 complex (Mis18α/Mis18β/Mis18BP1). Spatial and temporal regulation of Mis18 complex assembly is crucial for its centromere association and function. Here, we provide the molecular basis for the assembly and regulation of the Mis18 complex. We show that the N‐terminal region of Mis18BP1 spanning amino acid residues 20–130 directly interacts with Mis18α/β to form the Mis18 complex. Within Mis18α/β, the Mis18α MeDiY domain can directly interact with Mis18BP1. Mis18α/β forms a hetero‐hexamer with 4 Mis18α and 2 Mis18β. However, only two copies of Mis18BP1 interact with Mis18α/β to form a hetero‐octameric assembly, highlighting the role of Mis18 oligomerization in limiting the number of Mis18BP1 within the Mis18 complex. Furthermore, we demonstrate the involvement of consensus Cdk1 phosphorylation sites on Mis18 complex assembly and thus provide a rationale for cell cycle‐regulated timing of Mis18 assembly and CENP‐A deposition.
Ferrochelatase is a therapeutic target for ocular neovascularization
Authors: Basavarajappa Halesha D , Sulaiman Rania S , Qi Xiaoping , Shetty Trupti , Sheik Pran Babu Sardar , Sishtla Kamakshi L , Lee Bit , Quigley Judith , Alkhairy Sameerah , Briggs Christian M , Gupta Kamna , Tang Buyun , Shadmand Mehdi , Grant Maria B , Boulton Michael E , Seo Seung‐Yong , Corson Timothy W 
Published: April 2017

AbstractOcular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient populations necessitate discovery of new therapeutic targets. Using a forward chemical genetic approach, we identified the heme synthesis enzyme ferrochelatase (FECH) as necessary for angiogenesis in vitro and in vivo. FECH is overexpressed in wet AMD eyes and murine choroidal neovascularization; siRNA knockdown of Fech or partial loss of enzymatic function in the Fechm1Pas mouse model reduces choroidal neovascularization. FECH depletion modulates endothelial nitric oxide synthase function and VEGF receptor 2 levels. FECH is inhibited by the oral antifungal drug griseofulvin, and this compound ameliorates choroidal neovascularization in mice when delivered intravitreally or orally. Thus, FECH inhibition could be used therapeutically to block ocular neovascularization.
A consensus for occupational health management of healthcare workers infected with human immunodeficiency virus, hepatitis B virus, and / or hepatitis C virus
Authors: Ishimaru Tomohiro , Wada Koji , Smith Derek R 
Published: April 2017

Abstract
Occupational health management plays an important role in the prevention of provider-to-patient transmission in healthcare workers infected with human immunodeficiency virus (HIV), hepatitis B virus (HBV), and/or hepatitis C virus (HCV). Therefore, the Japan Society for Occupational Health’s Research Group on Occupational Health for Health Care Workers has proposed a consensus for the management of healthcare workers infected with HIV, HBV, and/or HCV based on recent evidence for each concerned group. The consensus recommends that: (1) employers in medical institutions should establish a policy of respecting the human rights of healthcare workers, management strategies for occupational blood exposure, and occupational health consultation; (2) occupational health staff should appropriately assess the risk of provider-to-patient transmission of HIV, HBV, and / or HCV infection and rearrange their tasks if necessary. When conducting risk assessment, occupational health staff should obtain informed consent and then cooperate with the physician in charge as well as infection control experts in the workplace; (3) healthcare workers infected with HIV, HBV, and/or HCV should disclose their employment to their treating physician and consult with their doctor regarding the need for special considerations at work; and (4) supervisors and colleagues in medical institutions should correctly understand the risks of HIV, HBV, and HCV infection and should not engage in any behavior that leads to discrimination against colleagues infected with HIV, HBV, and/or HCV.
Dolabellane diterpenes from the Caribbean soft corals Eunicea laciniata and Eunicea asperula and determination of their anti HSV-1 activity
Authors: Amaya García Fabián , Sanchez Nuñez Maria Leonisa , Ramos Freddy A. , Puyana Mónica , Nunes de Palmer Paixão Izabel Christina , Teixeira Valeria Laneuville , Castellanos Leonardo 
Published: April 2017

Los dolabellanos son diterpenos con importante actividad antiviral, la mayor parte de los estudios se han realizado con compuestos aislados de algas pardas del género Dictyota. Los corales blandos son también una importante fuente de dolabellanos, pero el potencial antiviral de éstos ha sido muy poco estudiado. Como parte de nuestra búsqueda de compuestos bioactivos a partir de fuentes marinas, se llevó a cabo el estudio químico de los dolabellanos presentes en los octocorales Eunicea laciniata y Eunicea asperula, recolectados en Santa Marta, Caribe colombiano. Los dolabellanos 1-6 fueron aislados del octocoral E. laciniata mientras que en E. asperula se encontraron los compuestos 2, 4 y 5. La elucidación estructural se llevó a cabo mediante experimentos de RMN, espectrometría de masas, rotación óptica y posterior comparación con reportes previos en la literatura. El análisis por CG-EM evidenció que la dolabellatrienona (2) se puede transformar en los compuestos 4 y 5 como producto del almacenamiento prolongado, no obstante, tales compuestos también estuvieron presentes en los extractos de los organismos estudiados. El compuesto 6 inhibió la replicación del VHS-1 (73,7% de inhibición en células infectadas a una concentración de 50 μM) sin efecto citotóxico (CC50 = 959), mostrando una citotoxicidad similar al Aciclovir®, un control positivo, por lo cual se perfila como un candidato para la realización de estudios adicionales sobre el potencial de los dolabellanos como agentes antivirales.
Does Studying in a Strong School Guarantee Good College Performance?
Authors: Popova Evgeniya , Sheina Marina 
Published: April 2017

The paper tests the hypothesis about better academic performance of graduates from stronger high schools and the nature of correlations between college students’ achievements and their high school performance (whether they performed on average better or worse than their peers) with due regard for school characteristics. Regression analysis is used to measure the relationship between college performance and USE (Unified State Exam) scores, the type of high school, and high school performance (while controlling for individual student characteristics), as well as the fact of receiving regional Governor’s scholarship in addition to student allowance. The sample includes 313 first-year Economics and Management students admitted to National Research University Higher School of Economics (Perm) in 2012 and 2013. Cumulative first-year GPA is used as an indicator of academic performance. As it turns out, graduating from an advanced high school or from a school with high average USE scores in mathematics provides no guarantee of better educational outcomes for firstyear students. High school performance correlates positively with academic achievements in college, the degree of relationship depending on school characteristics. Educational outcomes of students who performed better than average in low-performing schools can be explained by the high level of ntrinsic motivation typical of academically successful students. Therefore, ignoring the information on college performance of graduates from low-performing schools may lead to underestimating their academic achievement. The fact of receiving a Governor’s scholarship proves to be a significant performance factor for Management students only.
Academic Rankings — Where Are They Heading?
Authors: Siwinski Waldemar 
Published: April 2017

The global ranking system is in a state of violent transformation. We can already see the emerging contours of a new ranking system with the four distinguished elements: regional systems, customer-centered systems, multi-league systems, discipline-based systems. To reflect regional characteristics, including language, culture, global ranking systems should become regional ranking systems. To satisfy readers’ different expectations towards rankings, ranker-centered systems should become customer-centered ystems. To reflect different institutional missions; size, locations, current unified ranking systems, they should become multiple ranking systems. Institutional ranking systems should become discipline-based ranking systems in order to reflect disciplinary differences. One of the most significant directions of changes in rankings is a search for a way to include in the international rankings other missions than research; especially important here are such aspects as excellence in teaching and the so called third mission or the university’s social mission.
Application controlling of claims in the logistics company
Authors: Kormanova Lucia , Majercak Peter 
Published: April 2017

In the condition of the increasing complexity of the business systems and their environment is the controlling an essential basic of the success of each company. It is a phenomenon which integrates the information processing, the analysis processes, the preparation of the business plans and the control processes. Controlling is implemented into the company system by the broad range of the activities that are influencing all the sectors, departments and the levels of the management. This article is focused on the financial controlling and on the keeping the financial balance over the year. Each company knows that to be competitive and has high sales, ordinary needs to offer some kind of the trade credit to the customers. By the sales of the credit arises the difference between the cash and the bookkeeping sales. These sales are until the date of the payment from the financial aspect unfinished, thus resulting to the assets that need to be financed in a way but there is always the risk that supplier wonÂ´t pay on the time or at all. The aim of this paper is to present and to verify the complex model of the asset evaluation in the condition of the logistic company and its financial and economic consequences..

Keywords: financial controlling; controlling of claims; claims; working capital; logistics company;
Price Adjustments of Price-setting Factors under Sales Comparison Approach (SCA)
Authors: Cupal Martin 
Published: April 2017

The sales comparison approach (SCA) usually represents the most important valuation approach. Besides this approach, there are two other performing valuation approaches at other bases. The sales comparison is a set of procedures, in which an appraiser derives a value indication by comparing the property being appraised to similar properties. Real properties vary considerably from one another, which is reflected by price-setting factors. Although price adjustments (caused by differences projected into price by the grid adjustment technique) are always ad hoc, certain relations among the price-setting factors can be detected.The research is based on evaluating price adjustments across different types of real estate. In addition, its objective is to determine the values of simultaneous relations of price adjustments for individual price-setting factors. The methodology consists of three steps. The first one clearly defines the content of individual price-setting factors and price adjustments for further analysis. The second step involves statistical analysis of an extensive appraiser database and evaluation of price adjustments. The final step uses selected statistics to compare the LRM and the SCA and interprets mutual relations.The results of the research should have practical implications for professional appraisal community and further research analyses of the SCA.
Keywords: Sales comparison approach, price-setting factor, price adjustment, real estate;
A Survey of the Collaboration Rate of Authors in the E-Learning Subject Area over a 10-Year Period (2005-2014) Using Web of Science
Authors: Mohammadi Aeen , Asadzandi Shadi , Malgard Shiva 
Published: April 2017

<p>Partnership is one of the mechanisms of scientific development, and scientific collaboration or co-authorship is considered a key element in the progress of science. This study is a survey with a scientometric approach focusing on the field of e-learning products over 10 years. In an Advanced Search of the Web of Science, the following search formula was used: TS=("m-learning" OR "mlearning" OR "mobile learning" OR "online learning" OR "virtual learning" OR "distance learning" OR "electronic learning"). The study was limited to 2005-2014, and the document type was limited to paper. A total of 4292 documents were found, to which 12362 authors contributed. The articles were evaluated individually and their information was entered into Microsoft Office Excel 2007 for analysis using the collaborative coefficient formula. In the Computers and Education journal, articles with two authors are the most frequent. The United States, with the highest production of articles in the field of e-learning, tends to produce articles with two authors. In 2014, the most productive year, articles with three authors were more frequent. The highest collaborative coefficient is in 2005 and 2014. Our findings show that despite the need for research activities as a team, the authors in the field of e-learning tend to publish their papers alone or in a team of two.</p>
Randomized Controlled Trial of Interscalene Block Compared with Injectable Liposomal Bupivacaine in Shoulder Arthroplasty
Authors: Namdari Surena , Nicholson Thema , Abboud Joseph , Lazarus Mark , Steinberg Dean , Williams Gerald 
Published: April 2017

Background:
Shortcomings of interscalene brachial plexus blockade include technical failure and rebound pain. Bupivacaine liposome injectable suspension, a sustained release preparation, is used for surgical-site administration. The purpose of this study was to evaluate these 2 postoperative pain management strategies in patients undergoing shoulder arthroplasty.

Methods:
In a non-blinded, randomized controlled trial of participants undergoing primary shoulder arthroplasty, patients were randomized to interscalene brachial plexus blockade or intraoperative soft-tissue infiltration of bupivacaine liposome injectable suspension. The primary outcome variable was morphine equivalent units consumed over the first 24 hours postoperatively. Secondary outcomes included morphine equivalent units consumed intraoperatively and a visual analog scale (VAS) for pain at 0, 8, 16, and 24 hours.

Results:
Seventy-eight patients were randomized to interscalene brachial plexus blockade treatment (the blockade group) and 78 patients were randomized to bupivacaine liposome injectable suspension treatment (the suspension group). The mean total postoperative narcotic consumption (and standard deviation) over 24 hours after the surgical procedure was 14.8 ± 11.3 morphine equivalent units in the blockade group compared with 14.4 ± 16.8 morphine equivalent units in the suspension group (p = 0.849). Intraoperative narcotics were significantly lower (p < 0.001) in the blockade group (8.9 ± 4.1 morphine equivalent units) compared with the suspension group (16.2 ± 7.0 morphine equivalent units). The mean VAS pain score was significantly lower in the blockade group than in the suspension group at 0 hours postoperatively (0.8 ± 2.2 compared with 3.3 ± 2.7 points; p < 0.001) and at 8 hours postoperatively (1.4 ± 2.4 compared with 3.2 ± 2.2 points; p < 0.001), but it was not significantly different at 16 hours postoperatively (4.3 ± 2.8 compared with 3.8 ± 2.4 points; p = 0.348). The VAS pain scores were significantly higher (p = 0.021) in the blockade group (4.9 ± 2.7 points) compared with the suspension group (3.9 ± 2.3 points) at 24 hours postoperatively.

Conclusions:
Patients treated with bupivacaine liposome injectable suspension required an equivalent amount of postoperative narcotics and greater intraoperative narcotics compared with patients treated with interscalene brachial plexus blockade. Although interscalene brachial plexus blockade provided improved pain scores for the first 8 hours after the surgical procedure, pain scores were worse at 24 hours. The optimal postoperative pain regimen for shoulder arthroplasty and the cost-effectiveness of analgesic techniques require further investigation.

Level of Evidence:
Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.