bluuebunny/crossref_metadata_2025_split huggingface dataset:
A SEARCH FOR ELECTRON ANTINEUTRINOS ASSOCIATED WITH GRAVITATIONAL-WAVE EVENTS GW150914 AND GW151226 USING KAMLAND
Authors: Gando A. , Gando Y. , Hachiya T. , Hayashi A. , Hayashida S. , Ikeda H. , Inoue K. , Ishidoshiro K. , Karino Y. , Koga M. , Matsuda S. , Mitsui T. , Nakamura K. , Obara S. , Oura T. , Ozaki H. , Shimizu I. , Shirahata Y. , Shirai J. , Suzuki A. , Takai T. , Tamae K. , Teraoka Y. , Ueshima K. , Watanabe H. , Kozlov A. , Takemoto Y. , Yoshida S. , Fushimi K. , Piepke A. , Banks T. I. , Berger B. E. , Fujikawa B. K. , O’Donnell T. , Learned J. G. , Maricic J. , Sakai M. , Winslow L. A. , Krupczak E. , Ouellet J. , Efremenko Y. , Karwowski H. J. , Markoff D. M. , Tornow W. , Detwiler J. A. , Enomoto S. , Decowski M. P. ,   The KamLAND Collaboration
Published: September 2016

ABSTRACT
We present a search, using KamLAND, a kiloton-scale anti-neutrino detector, for low-energy anti-neutrino events that were coincident with the gravitational-wave (GW) events GW150914 and GW151226, and the candidate event LVT151012. We find no inverse beta-decay neutrino events within ±500 s of either GW signal. This non-detection is used to constrain the electron anti-neutrino fluence and the total integrated luminosity of the astrophysical sources.
Percutaneous Transhepatic Embolization of Bleeding Rectal Varices Using A New Embolic And Sclerotic Mixture Augmented By Amplatzer Vascular Plug 2
Authors: Abdel Aal Ahmed Kamel , Dawoud Nabila , Moustafa Amr Soliman , Hamed Maysoon F , Saddekni Souheil 
Published: September 2016

We report a case of 59-year-old female with non-alcoholic-steato-hepatitis (NASH) induced cirrhosis, who presented with hematochezia. The patient had a history of bleeding esophageal varices treated with endoscopic variceal ligation (EVL). Colonoscopy showed large rectal varices which were the source of her lower gastrointestinal bleeding (LGIB). Since endoscopic treatment for LGIB are limited, and because the patient had portal vein thrombosis which contraindicated transjugular intrahepatic portosystemic shunt (TIPS), we performed percutaneous transhepatic embolization of her rectal varices using a new mixture of embolic and sclerotic agents, followed by Amplatzer plug 2 (AVP 2). To our knowledge, the use of this new mixture with the AVP 2 in the rectal varices treatment has not been previously published in literature. Our case provides an alternative treatment modality that can be used for rectal varices treatment, when TIPS and endoscopic management fails or is contraindicated.
High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques
Authors: Kannanganat Sunil , Wyatt Linda S. , Gangadhara Sailaja , Chamcha Venkatesarlu , Chea Lynette S. , Kozlowski Pamela A. , LaBranche Celia C. , Chennareddi Lakshmi , Lawson Benton , Reddy Pradeep B. J. , Styles Tiffany M. , Vanderford Thomas H. , Montefiori David C. , Moss Bernard , Robinson Harriet L. , Amara Rama Rao 
Published: September 2016

Abstract
We tested, in rhesus macaques, the effects of a 500-fold range of an admixed recombinant modified vaccinia Ankara (MVA) expressing rhesus GM-CSF (MVA/GM-CSF) on the immunogenicity and protection elicited by an MVA/SIV macaque 239 vaccine. High doses of MVA/GM-CSF did not affect the levels of systemic envelope (Env)-specific Ab, but it did decrease the expression of the gut-homing receptor α4β7 on plasmacytoid dendritic cells (p &lt; 0.01) and the magnitudes of Env-specific IgA (p = 0.01) and IgG (p &lt; 0.05) in rectal secretions. The protective effect of the vaccine was evaluated using 12 weekly rectal challenges in rhesus macaques subgrouped by tripartite motif-containing protein 5α (TRIM5α) genotypes that are restrictive or permissive for infection by the challenge virus SIVsmE660. Eight of nine TRIM5α-restrictive animals receiving no or the lowest dose (1 × 105 PFU) of MVA/GM-CSF resisted all 12 challenges. In the comparable TRIM5α-permissive group, only 1 of 12 animals resisted all 12 challenges. In the TRIM5α-restrictive animals, but not in the TRIM5α-permissive animals, the number of challenges to infection directly correlated with the magnitudes of Env-specific rectal IgG (r = +0.6) and IgA (r = +0.6), the avidity of Env-specific serum IgG (r = +0.5), and Ab dependent cell-mediated virus inhibition (r = +0.6). Titers of neutralizing Ab did not correlate with protection. We conclude that 1) protection elicited by MVA/SIVmac239 is strongly dependent on the presence of TRIM5α restriction, 2) nonneutralizing Ab responses contribute to protection against SIVsmE660 in TRIM5α-restrictive animals, and 3) high doses of codelivered MVA/GM-CSF inhibit mucosal Ab responses and the protection elicited by MVA expressing noninfectious SIV macaque 239 virus-like particles.
Adipose Tissue Dendritic Cells Are Independent Contributors to Obesity-Induced Inflammation and Insulin Resistance
Authors: Cho Kae Won , Zamarron Brian F. , Muir Lindsey A. , Singer Kanakadurga , Porsche Cara E. , DelProposto Jennifer B. , Geletka Lynn , Meyer Kevin A. , O’Rourke Robert W. , Lumeng Carey N. 
Published: September 2016

Abstract
Dynamic changes of adipose tissue leukocytes, including adipose tissue macrophage (ATM) and adipose tissue dendritic cells (ATDCs), contribute to obesity-induced inflammation and metabolic disease. However, clear discrimination between ATDC and ATM in adipose tissue has limited progress in the field of immunometabolism. In this study, we use CD64 to distinguish ATM and ATDC, and investigated the temporal and functional changes in these myeloid populations during obesity. Flow cytometry and immunostaining demonstrated that the definition of ATM as F4/80+CD11b+ cells overlaps with other leukocytes and that CD45+CD64+ is specific for ATM. The expression of core dendritic cell genes was enriched in CD11c+CD64− cells (ATDC), whereas core macrophage genes were enriched in CD45+CD64+ cells (ATM). CD11c+CD64− ATDCs expressed MHC class II and costimulatory receptors, and had similar capacity to stimulate CD4+ T cell proliferation as ATMs. ATDCs were predominantly CD11b+ conventional dendritic cells and made up the bulk of CD11c+ cells in adipose tissue with moderate high-fat diet exposure. Mixed chimeric experiments with Ccr2−/− mice demonstrated that high-fat diet–induced ATM accumulation from monocytes was dependent on CCR2, whereas ATDC accumulation was less CCR2 dependent. ATDC accumulation during obesity was attenuated in Ccr7−/− mice and was associated with decreased adipose tissue inflammation and insulin resistance. CD45+CD64+ ATM and CD45+CD64−CD11c+ ATDCs were identified in human obese adipose tissue and ATDCs were increased in s.c. adipose tissue compared with omental adipose tissue. These results support a revised strategy for unambiguous delineation of ATM and ATDC, and suggest that ATDCs are independent contributors to adipose tissue inflammation during obesity.
A Tetravalent Formulation Based on Recombinant Nucleocapsid-like Particles from Dengue Viruses Induces a Functional Immune Response in Mice and Monkeys
Authors: Gil Lázaro , Cobas Karem , Lazo Laura , Marcos Ernesto , Hernández Laura , Suzarte Edith , Izquierdo Alienys , Valdés Iris , Blanco Aracelys , Puentes Pedro , Romero Yaremis , Pérez Yusleidi , Guzmán María G. , Guillén Gerardo , Hermida Lisset 
Published: September 2016

Abstract
Despite the considerable effort that has been invested in elucidating the mechanisms of protection and immunopathogenesis associated with dengue virus infections, a reliable correlate of protection against the disease remains to be found. Neutralizing Abs, long considered the prime component of a protective response, can exacerbate disease severity when present at subprotective levels, and a growing body of data is challenging the notion that their titers are positively correlated with disease protection. Consequently, the protective role of cell-mediated immunity in the control of dengue infections has begun to be studied. Although earlier research implicated cellular immunity in dengue immunopathogenesis, a wealth of newer data demonstrated that multifunctional CD8+ T cell responses are instrumental for avoiding the more severe manifestations of dengue disease. In this article, we describe a new tetravalent vaccine candidate based on recombinant dengue virus capsid proteins, efficiently produced in Escherichia coli and purified using a single ion-exchange chromatography step. After aggregation to form nucleocapsid-like particles upon incubation with an oligodeoxynucleotide containing immunostimulatory CpG motifs, these Ags induce, in mice and monkeys, an IFN-γ–secreting cell response that significantly reduces viral load after challenge without the contribution of antiviral Abs. Therefore, this new vaccine candidate may not carry the risk for disease enhancement associated with Ab-based formulations.
A case report of acampomelic campomelic dysplasia and operative difficulties in cleft palate reconstruction
Authors: Pasupathy M. , Radhakrishnan Vasant , Adenwalla Hirji Sorab , Narayanan Puthucode V. 
Published: September 2016

ABSTRACTAcampomelic campomelic dysplasia (CD) is a type of CD (CD; OMIM #114290), a rare form of congenital short-limbed dwarfism and is due to mutations in SOX9 gene family. Characteristic phenotypes of CD include bowing of the lower limbs, a narrow thoracic cage, 11 pairs of ribs, hypoplastic scapulae, macrocephaly, flattened supraorbital ridges and nasal bridge, cleft palate and micrognathia. The bending of the long bones is not an obligatory feature and is absent in about 10% of cases, referred to as acampomelic CD. A child previously diagnosed with acampomelic CD was brought to our outpatient clinic for cleft palate reconstruction. Our neurosurgeon cautioned us against performing surgery with extension of the neck in view of the possibility of producing quadriparesis, due to narrowing of the spinal canal as part of the osseous anomaly noted in the magnetic resonance imaging study of the spine, thus making the anaesthesia, surgical and post-operative procedures difficult. The cleft palate reconstruction was performed with all precautions and was uneventful.
Algorithmic surgical enhancement of function after finger revascularisation
Authors: Landin Luis , Bolado Pedro , Gajete Maria-Angeles , Gonzalez-Miranda Alvaro , Bonastre Jorge 
Published: September 2016

ABSTRACTSecondary surgical procedures can improve the function of revascularised and replanted digits. We describe the case of a patient who underwent multidigit revascularisation and replantation following a saw injury at flexor tendon Zone II. To achieve maximal functional improvement after finger revascularisation, we performed secondary surgical procedures in an order that was determined by following a reconstructive decision procedure that covered late revascularisation, nerve reconstruction, pedicled vascularised joint transfer, staged flexor tendon reconstruction and skin revision. Performing the procedures in this manner ensured overall safety. The patient’s disabilities of the arm, hand and shoulder questionnaire score improved by 45 points, and the patient was able to return to work with an almost complete range of motion.
Antibiotic susceptibility of wound isolates in plastic surgery patients at a tertiary care centre
Authors: Patil Surendra B. , Paramne Amit , Harsh Shree 
Published: September 2016

ABSTRACT
Context: Wound infection increases the hospital stay and adversely affects the recovery of patients. Culture and sensitivity of wound isolates help in proper diagnosis and management of these patients. Aim: To identify common bacteria causing wound infections and their antibiotic sensitivity pattern. Study Design: A cross-sectional study. Place and Duration of Study: Government Medical College and Hospital, Nagpur from October 2013 to October 2015. Materials and Methods: Pus samples were collected by doctors in ward using Sterile Swab Sticks. Bacterial isolates were identified and cultured, and antibiotic culture sensitivity tests were performed. Statistical Analysis Used: Chi-square test. Results: There were a total of 150 patients with infected wounds. Most common organism isolated was Pseudomonas followed by Klebsiella and Staphylococcus aureus. All of these organisms were resistant to most routine antibiotics. Conclusion: We suggest a multidisciplinary approach to wound management, rational drug use, routine microbiological surveillance of wounds and institution of hospital infection control policy.
On the Asymptotic Growth of
Bloch-Kato-Shafarevich-Tate Groups of
Modular Forms Over Cyclotomic
Extensions
Authors: Lei Antonio , Loeffler David , Sarah Livia Zerbes 
Published: September 2016

AbstractWe study the asymptotic behaviour of the Bloch-Kato-Shafarevich-Tate group of a modular form f over the cyclotomic ℤp-extension of ℚ under the assumption that f is non-ordinary at p. In particular, we give upper bounds of these groups in terms of Iwasawa invariants of Selmer groups defined using p-adic Hodge Theory. These bounds have the same form as the formulae of Kobayashi, Kurihara, and Sprung for supersingular elliptic curves.
Is African science true science? Reflections on the methods of African science
Authors: Afisi Oseni Taiwo 
Published: September 2016

The general character of science and the methodology it employs are in specific terms referred to as observation and experimentation. These two methodologies reflect how science differs from other systematic modes of inquiries. This description characterises, strictly, ‘Western science’ and it is contrasted with the indigenous mode of enquiry that has come under the name, ‘African science’. In contemporary scholarship, ‘African science’ is being condemned to the level of the mysticoreligious or supernaturalist worldview. ‘African science’ is said to be purely esoteric, personal, and devoid of elements of objectivity and rigorous theorization. In this paper, I re-examine this recondite issue by further reflecting and strengthening some of the ideas put forward by some African scholars to affirm that there is a distinct method of ‘African science’ that can be termed scientific. In defending a pluralist thesis toward knowledge, scientific inclusive, this paper posits that there exist varieties of inquiry beyond what has been developed in the ‘West’ which can still be justifiably termed scientific. In addition to pluralism, it argues further that the social character of science, which makes it a part of social and cultural traditions, qualifiedly justifies ‘African science’ as a true science. I will employ the newly formulated conversational method endorsed by the Conversational School of Philosophy (CSP) in this inquiry.Keywords: African science, mystico-religious, rigorous, pluralism, Western science
Innocent Onyewuenyi’s “Philosophical re-appraisal of the African belief in reincarnation”: A conversational study
Authors: Edet Mesembe Ita 
Published: September 2016

Reincarnation has received substantial treatment in African philosophy. The dominant view of African scholars and researchers on the subject is that it is a belief that prevails in African culture. The task of this paper is to revisit Innocent Onyewuenyi’s “philosophical reappraisal” of this African belief. Onyewuenyi’s position is that the African communion with ancestors and their influence on their living descendant’s has been incorrectly labeled “reincarnation” by Western anthropologists. But whereas Onyewuenyi portrays the problem as being one of semantics, I shall in this paper argue that the challenge of explaining African cultural phenomenon is one of hermeneutics. The question is a question of hermeneutics, because its focus is not on whether ancestors are metaphysical entities, but rather on what they mean within African existence. The paper adopts the conversational method of African philosophy endorsed by the Conversational School of Philosophy. It aims to show how conversationalism as a procedure of philosophical discourse plays out within the context of its specific canons. In the final analysis the paper promotes the thesis that there is not a belief in reincarnation in African culture strictly speaking, but a belief in the regeneration of life. For the African, life is not cyclical, it is rather eternal.Keywords: Innocent Onyewuenyi, reincarnation, conversationalism, hermeneutics, African metaphysics, living-dead, regeneration of life.
Documentación del patrimonio cultural. Método basado en la fusión de técnicas fotogramétricas y de escaneado óptico de triangulación
Authors: Molero Alonso Borja , Barba Salvatore , Álvaro Tordesillas Antonio 
Published: September 2016

<p>Los continuos avances en los últimos años de equipos de levantamiento tridimensional han aumentado el abanico de posibilidades para el registro, documentación y difusión del patrimonio. Pero, y desde esta hipótesis partimos, aún existen obstáculos para la creación de modelos 3D fotorrealísticos y fidedignos en algunos ámbitos geométricos y radiométricos. Estos aparecen cuando las características de las piezas son adversas para su digitalización, es decir, la geometría del objeto carece de aristas definidas y/o su acabado no permite su registro, bien por su color, uniformidad, reflectancia, etc. Este estudio plantea y presenta resultados de un modelo fotorrealístico aplicado al levantamiento de una escultura de Jorge Oteiza. Obra caracterizada por una geometría y textura desfavorables a las ideales para su digitalización. La solución planteada pasa por una metodología fundamentada en la combinación de técnicas: modelos capturados mediante escáner óptico de triangulación Artec con el apoyo del software fotogramétrico PhotoScan en la fase de texturización.</p>
The lasting mental health effects of Hurricane Sandy on residents of the Rockaways
Authors: Schwartz, PhD Rebecca M. , Rothenberg, BA Patricia , Kerath, MS Samantha M. , Liu, PhD Bian , Taioli, MD, PhD Emanuela 
Published: September 2016

Objective: To examine the impact of Hurricane Sandy on the mental health and substance use of residents of the Rockaways, which is a lower income, ethnically diverse region of NYC that was devastated by the hurricane. Design: Prospective, cross sectional. Setting: Rockaways, Queens, NYC community residents. Participants: From October 2013 to April 2015, 407 adult residents of the Rockaways completed self-report, validated measures of depression, anxiety, and post-traumatic stress symptoms as well as indicators of substance use (alcohol, illicit substance, and tobacco use) and exposure to Hurricane Sandy. Main Outcome Measures: Depression, anxiety, post-traumatic stress, alcohol use, illicit substance use, and tobacco use. Results: Differences in exposure scores on outcomes were compared using Wilcoxon tests. Associations between hurricane exposure (categorized into “personal” and “property” exposure) and outcomes were investigated using logistic regression, adjusting for demographic covariates, mental health history, and time since hurricane. The study participants were predominately female (57.5 percent) and black (63.9 percent) and average age was 44.7 years. Multivariable results showed that property exposure scores were positively associated with increased risks of mental health difficulties across all three mental health symptom outcomes, but not substance use. Increased personal and total exposures were also significantly associated with increased Posttraumatic Stress Disorder symptoms. Substance use variables were not significantly associated with any of the hurricane exposure indicators. Conclusions: The present study quantifies the lasting impact that Hurricane Sandy has had on the mental health of Rockaways residents indicating the need for continued recovery efforts and increased mental health service provision in this vulnerable region.
Meteorological constraints on oceanic halocarbons above the Peruvian
upwelling
Authors: Fuhlbrügge Steffen , Quack Birgit , Atlas Elliot , Fiehn Alina , Hepach Helmke , Krüger Kirstin 
Published: September 2016

Abstract. During a cruise of R/V METEOR in December 2012 the oceanic sources and emissions of various halogenated trace gases and their mixing ratios in the marine atmospheric boundary layer (MABL) were investigated above the Peruvian upwelling. This study presents novel observations of the three very short lived substances (VSLSs) – bromoform, dibromomethane and methyl iodide – together with high-resolution meteorological measurements, Lagrangian transport and source–loss calculations. Oceanic emissions of bromoform and dibromomethane were relatively low compared to other upwelling regions, while those for methyl iodide were very high. Radiosonde launches during the cruise revealed a low, stable MABL and a distinct trade inversion above acting as strong barriers for convection and vertical transport of trace gases in this region. Observed atmospheric VSLS abundances, sea surface temperature, relative humidity and MABL height correlated well during the cruise. We used a simple source–loss estimate to quantify the contribution of oceanic emissions along the cruise track to the observed atmospheric concentrations. This analysis showed that averaged, instantaneous emissions could not support the observed atmospheric mixing ratios of VSLSs and that the marine background abundances below the trade inversion were significantly influenced by advection of regional sources. Adding to this background, the observed maximum emissions of halocarbons in the coastal upwelling could explain the high atmospheric VSLS concentrations in combination with their accumulation under the distinct MABL and trade inversions. Stronger emissions along the nearshore coastline likely added to the elevated abundances under the steady atmospheric conditions. This study underscores the importance of oceanic upwelling and trade wind systems on the atmospheric distribution of marine VSLS emissions.