bluuebunny/crossref_metadata_2025_split huggingface dataset:
The comparative basis of intensification
Authors: König Ekkehard 
Published: October 2017

Abstract
This paper argues that the ubiquitous cognitive process of comparing and the resultant judgements of similarity and dissimilarity also underlie the semantic processes of intensification and grading to a large extent. This comparative basis is visible both in the formal properties of many intensifiers and in central aspects of their semantics: Intensifiers may overtly encode a comparison (e.g. crystal clear, royally, outstanding) and an emotional reaction to a comparison (surprisingly, frightfully), or they may imply a comparison with a covert standard in endocentric expansions of simple adjectival predications. In order to gain a new perspective on their meaning, the relations between intensifiers, on the one hand, and demonstratives, exclamatives and comparative constructions, on the other, are analyzed and a semantic typology of comparative constructions is outlined and discussed in relation to the central hypothesis.
Intensification strategies in German and Italian written language
Authors: Calpestrati Nicolò 
Published: October 2017

Abstract
The aim of this study is to investigate a group of six Fremdpräfixe or prefissi intensivi within the context of intensification and to observe both how they work and are perceived by native Italian and German speakers. This work is structured in two parts: the first part is made up of a structured questionnaire to investigate how such prefixes are considered and evaluated from speakers of both languages with the aim of creating an intensity scale. The second part investigates the combinability of the foreign prefixes with specific stems and their presence in a corpus of written language: COSMASII Korpus (IDS Mannheim) for German and CORIS/CODIS Corpus (University of Bologna) for Italian.
Intentional vagueness
Authors: Voghera Miriam , Collu Laura 
Published: October 2017

Abstract
In this article, we present a corpus-based analysis to illustrate the extent and the depth of the similarities in the use of Vagueness Expressions (VEs) in spoken Italian and German. Adopting a semiotic approach to the study of vagueness, we have investigated the frequency and the distribution of VEs, conveying informational, relational and discourse vagueness in conversations, non-free-dialogues and monologues. The two languages do not exhibit the same qualitative and quantitative distribution of VEs because (a) German has twice as many VEs as Italian and (b) in Italian VEs are fairly limited to spontaneous conversations, while German speakers use VEs in all kinds of texts conveying the three types of Vagueness. This suggests that in German VEs are part of the linguistic norm, and not only a choice on the part of the speaker.
Morphosyntactic defectiveness in complex predicate formation
Authors: Espinal M.Teresa 
Published: October 2017

Abstract
This article focuses on verb valency change in complex predicate formation by noun incorporation. I reassess the claim that incorporated nouns and clitics in both Uto-Aztecan and Romance languages are morphosyntactically defective, and I show that crucially morphosyntactic defectiveness, but not semantic prototypicality is a necessary condition in many natural languages in order to identify formally those nominal expressions that are to be interpreted as property-denoting expressions and event predicate modifiers, rather than as canonical syntactic and semantic arguments.
The semantics of Nahuatl tla- constructions
Authors: Navarro Ía 
Published: October 2017

Abstract
Nahuatl tla- constructions are described as complex predicates formed by a verbal base and an unspecified object pronoun that has weakened its formal status in favor of an abstract semantic contribution. We propose that the formal status of tla- is that of a defective pronoun, which fails to make a formal contribution in favor of a semantic one and causes the verbal base to be interpreted in a specific fashion. Furthermore, we show that the meaning of the resulting complex constructions depends on both, the tla- semantic contribution and the verbal base semantic and configurational properties. Based on descriptive and theoretical background, we disagree with tla- being categorized as an antipassive marker – as others propose –, instead we suggest that tla- constructions are the result of an event modification process and that the outcome of this process depends on how the operation interacts with the verbal base lexical properties.
Valency-changing operations in Yaqui resultatives
Authors: Álvarez González Albert 
Published: October 2017

Abstract
This paper describes the resultative constructions existing in Yaqui (Uto-Aztecan) and discusses the valency issues involved in these constructions. The study shows that Yaqui has five different syntactic types of resultatives: S-, A- and bivalent S-resultatives marked by the suffix -(l)a, and P- and R-resultatives marked by the suffix -(r)i. The analysis of the different valency-changing operations present in these constructions demonstrates that the -(l)a resultativization does not trigger a valency change, contrary to the -(r)i resultativization that always implies a valency decreasing operation. More specifically, it is shown that P-resultatives and personal passives exhibit a functional overlap, that R-resultatives are derived from an applicative construction, and that the bivalent S-resultative is in fact an externally possessed S-resultative that can be considered an external possession construction if the base verb is a non-derived intransitive verb root and if the possessive relation is an inanimate inalienable possession. As for the suffix -la used in A-resultatives, some evidences indicate that it is in the process of being grammaticalized as a perfect/anterior marker in Yaqui.
Valency-decreasing operations in a valency-increasing language?
Authors: Lander Yury , Letuchiy Alexander 
Published: October 2017

Abstract
This paper surveys valency-changing operations in West Circassian (Adyghe), a polysynthetic language of the Northwest Caucasian family. This language has an amazing number of means to increase valency, which include various kinds of applicativization and causativization. In this paper we also present processes which may look valency-decreasing and argue that they do not necessarily remove arguments, even though some of them change transitivity. This implies, in particular, the need for distinguishing between valency change and transitivity change.
MALDIrppa: quality control and robust analysis for mass spectrometry data
Authors: Palarea-Albaladejo Javier , Mclean Kevin , Wright Frank , Smith David G E 
Published: October 2017

Abstract

Summary
This R package helps to implement a robust approach to deal with mass spectrometry (MS) data. It is aimed at alleviating reproducibility issues and pernicious effects of deviating signals on both data pre-processing and downstream data analysis. Based on robust statistical methods, it facilitates the identification and filtering of low-quality mass spectra and atypical peak profiles as well as monitoring and data handling through pre-processing, which extends existing computational tools for high-throughput data.

Availability and implementation
MALDIrppa is implemented as a package for the R environment for data analysis and it is freely available to download from the CRAN repository at https://CRAN.R-project.org/package=MALDIrppa.
Cdc42 regulates the cellular localization of Cdc42ep1 in controlling neural crest cell migration
Authors: Cohen Shlomi , Kovari Daniel T , Wei Wenbin , Keate Rebecca , Curtis Jennifer E , Nie Shuyi 
Published: October 2017

AbstractThe member of Rho family of small GTPases Cdc42 plays important and conserved roles in cell polarity and motility. The Cdc42ep family proteins have been identified to bind to Cdc42, yet how they interact with Cdc42 to regulate cell migration remains to be elucidated. In this study, we focus on Cdc42ep1, which is expressed predominantly in the highly migratory neural crest cells in frog embryos. Through morpholino-mediated knockdown, we show that Cdc42ep1 is required for the migration of cranial neural crest cells. Loss of Cdc42ep1 leads to rounder cell shapes and the formation of membrane blebs, consistent with the observed disruption in actin organization and focal adhesion alignment. As a result, Cdc42ep1 is critical for neural crest cells to apply traction forces at the correct place to migrate efficiently. We further show that Cdc42ep1 is localized to two areas in neural crest cells: in membrane protrusions together with Cdc42 and in perinuclear patches where Cdc42 is absent. Cdc42 directly interacts with Cdc42ep1 (through the CRIB domain) and changes in Cdc42 level shift the distribution of Cdc42ep1 between these two subcellular locations, controlling the formation of membrane protrusions and directionality of migration as a consequence. These results suggest that Cdc42ep1 elaborates Cdc42 activity in neural crest cells to promote their efficient migration.
First Report of Embellisia allii Causing Skin Blotch and Bulb Canker on Garlic in Montana
Authors: Lonergan Erin , Skoglund Linnea G. 
Published: October 2017

Embellisia allii has been reported on garlic (Allium sativum L.) worldwide. It was most recently reported in California in 2012. E. allii is not restricted to garlic and has been shown to also infect leek and onion. This is the first report of E. allii causing bulb canker in garlic in Montana. Accepted for publication 21 August 2013. Published 24 September 2013.
Characterization of Resistance of Peanut to Puccinia arachidis
Authors: Power Imana L. , Culbreath Albert K. , Tillman Barry L. 
Published: October 2017

Peanut rust, caused by Puccinia arachidis Speg, is an important foliar disease of peanut (Arachis hypogaea L.) in tropical countries. The best option for disease management is host resistance. The objectives of this project included characterizing peanut genotypes for resistance to P. arachidis, assessing the genetic variation of newly developed Collaborative Research and Support Program (CRSP) peanut breeding lines, and assessing genetic variability among P. arachidis populations. In field studies conducted over 2010-2011, several CRSP breeding lines demonstrated varying levels of rust resistance. Detached leaf assays were used to examine the components of resistance to P. arachidis. Few significant differences were observed in these studies. We used SSR markers to characterize newly developed CRSP breeding lines, plant introductions, and commonly grown cultivars. The SSR markers used detected polymorphisms but were not able to distinguish resistant from susceptible peanut genotypes. Sequences of the 5.8S-ITS2-28S region of P. arachidis isolates collected from different regions in the United States and other countries do not indicate high genetic variability among the populations. Accepted for publication 23 September 2013. Published 25 November 2013.
Learning naturalistic temporal structure in the posterior medial network
Authors: Aly Mariam , Chen Janice , Turk-Browne Nicholas B. , Hasson Uri 
Published: October 2017

AbstractThe posterior medial network is at the apex of a temporal integration hierarchy in the brain, integrating information over many seconds of viewing intact, but not scrambled, movies. This has been interpreted as an effect of temporal structure. Such structure in movies depends on pre-existing event schemas, but temporal structure can also arise de novo from learning. Here we examined the relative role of schema-consistent temporal structure and arbitrary but consistent temporal structure on the human posterior medial network. We tested whether, with repeated viewing, the network becomes engaged by scrambled movies with temporal structure. Replicating prior studies, posterior medial regions were immediately locked to stimulus structure upon exposure to intact but not scrambled movies. However, for temporally structured scrambled movies, functional coupling within the network increased across stimulus repetitions, rising to the level of intact movies. Thus, temporal structure is a key determinant of network dynamics and function in the posterior medial network.
Assessment of the need for separate test set and number of medical images necessary for deep learning: a sub-sampling study
Authors: Rokem Ariel , Wu Yue , Lee Aaron 
Published: October 2017

AbstractDeep learning algorithms have tremendous potential utility in the classification of biomedical images. For example, images acquired with retinal optical coherence tomography (OCT) can be used to accurately classify patients with adult macular degeneration (AMD), and distinguish them from healthy control patients. However, previous research has suggested that large amounts of data are required in order to train deep learning algorithms, because of the large number of parameters that need to be fit. Here, we show that a moderate amount of data (data from approximately 1,800 patients) may be enough to reach close-to-maximal performance in the classification of AMD patients from OCT images. These results suggest that deep learning algorithms can be trained on moderate amounts of data, provided that images are relatively homogenous, and the effective number of parameters is sufficiently small. Furthermore, we demonstrate that in this application, cross-validation with a separate test set that is not used in any part of the training does not differ substantially from cross-validation with a validation data-set used to determine the optimal stopping point for training.
Adenylate kinase-4 modulates oxidative stress and stabilizes HIF-1α to drive lung cancer metastasis
Authors: Jan Yi-Hua , Lai Tsung-Ching , Yang Chih-Jen , Lin Yuan-Feng , Huang Ming-Shyan , Hsiao Michael 
Published: October 2017

AbstractDisrupting signaling axes that are essential for tumor metastasis may provide therapeutic opportunity to cure cancer. We previously identified adenylate kinase 4 (AK4) as a biomarker of metastasis in lung cancer. Here we analyze AK4-associated metabolic gene signature and reveal HIF-1α is transcriptionally activated and associated with poor prognosis in lung adenocarcinoma patients. Overexpression of AK4 shifts metabolism towards aerobic glycolysis and elevates intracellular reactive oxygen species (ROS), which stabilizes and exaggerates HIF1-α protein expression and concurrently drives epithelial-to-mesenchymal transition (EMT) in hypoxia. Furthermore, overexpression of AK4 reduces hypoxic necrosis in tumors and promotes liver metastasisin vivo. Connectivity map analysis of AK4 gene signature identifies Withaferin-A as a potential compound to inhibit AK4-HIF-1α signaling axis, which then shows promising anti-metastatic potency in an orthotopic xenograft model of lung cancer. Our findings offer an alternative strategy to impair lung cancer metastasis via targeting AK4-HIF-1α axis.
Multiple temporal perspectives extend sustainable competitiveness
Authors: Klassen Robert , Hajmohammad Sara 
Published: October 2017

PurposeIn operations and supply chain management, time is largely one-dimensional – less is better – with much effort devoted to compressing, efficiently using, and competitively exploiting clock-time. However, by drawing on other literatures, the purpose of this paper is to understand implications for the field of operations management if we also emphasize how humans and organizations experience time, termed process-time, which is chronicled by events and stages of change.Design/methodology/approachAfter a brief review, the limitations of the recurrent time-oriented themes in operations management and the resulting short-termism are summarized. Next, sustainability is offered as an important starting point to explore the concept of temporality, including both clock- and process-time, as well as the implications of temporal orientation and temporal conflict in supply chains.FindingsA framework that includes both management and stakeholder behavior is offered to illustrate how multiple temporal perspectives might be leveraged as a basis for an expanded and enriched understanding of more sustainable competitiveness in operations.Social implicationsResearch by others emphasizes the importance of stakeholders to competitiveness. By recognizing that different stakeholder groups have varying temporal orientations and temporality, managers can establish objectives and systems that better reflect time-based diversity and diffuse temporal conflict.Originality/valueThis paper summarizes how time has been incorporated in operations management, as well as the challenges of short-termism. Sustainability forms the basis for exploring multiple perspectives of time and three key constructs: temporal orientation, temporality, and temporal conflict. A framework is proposed to better incorporate temporal perspectives as a basis for competitiveness in operations and supply chain management.
Relevance of humanitarian logistics research: best practices and way forward
Authors: Kunz Nathan , Van Wassenhove Luk N. , Besiou Maria , Hambye Christophe , Kovács Gyöngyi 
Published: October 2017

Purpose
This paper is based on a panel discussion at EurOMA 2015. The purpose of this paper is to identify a number of barriers to relevant research in humanitarian logistics. The authors propose a charter of ten rules for conducting relevant humanitarian research.

Design/methodology/approach
The authors use operations management literature to identify best practices for doing research with practice. The authors compile, condense and interpret opinions expressed by three academics and one practitioner at the panel discussion, and illustrate them through quotes.

Findings
The increasing volume of papers published in the humanitarian logistics literature has not led to a proportional impact on practice. The authors identify a number of reasons for this, such as poor problem definition, difficult access to data or lack of contextualization. The authors propose a charter of ten rules that have the potential to make humanitarian logistics research more relevant for practice.

Practical implications
By developing best practices for doing relevant research in humanitarian logistics, this paper enables the academic community and practice to better work together on relevant and impactful research projects. Academic knowledge combined with practice-inspired problems has the potential to generate significant improvements to humanitarian practice.

Originality/value
This paper is the first to address the problem of relevance of humanitarian logistics research. It is also one of the few papers involving a practitioner to discuss practical relevance of research. Through this unique approach, it is hoped that this paper provides a set of particularly helpful recommendations for researchers studying humanitarian logistics.
Investigating the factors influencing cultural adjustment and expatriate performance
Authors: Sambasivan Murali , Sadoughi Morvarid , Esmaeilzadeh Pouyan 
Published: October 2017

Purpose
The fundamental question addressed in this research is: How do cultural intelligence, personality traits of expatriates, spousal support and cultural adjustment of expatriates impact their performance? The answer to the question is important to ensure that expatriation is successful. The paper aims to discuss these issues.

Design/methodology/approach
The integrated framework linking the factors was formulated and tested among the 139 expatriates employed by multinational corporations (MNC) in Malaysia. A questionnaire was developed and distributed. The framework was validated using structural equation modeling technique.

Findings
Based on the analysis, the important findings are: cultural empathy and social initiatives (personality traits) of expatriates, cultural intelligence and spousal support enhance cultural adjustment of expatriates; spousal support, cultural empathy and social initiatives influence the cultural intelligence of the expatriates; and cultural intelligence and spousal support impact the performance of expatriates.

Research limitations/implications
This study selected the expatriates working in MNCs and residing in Malaysia for six months and above.

Originality/value
This integrated view helps us understand the mechanism that leads to an expatriate’s perceived performance. Generally, researchers use “Big Five” to capture the personality traits. This research has used the construct and its dimensions that are relevant for studies on expatriation.
The sticky cost phenomenon at the local government level: empirical evidence from Greece
Authors: Cohen Sandra , Karatzimas Sotirios , Naoum Vassilios-Christos 
Published: October 2017

PurposeThe purpose of this paper is to explore the asymmetric cost behaviour in Greek local governments. More precisely, it investigates whether municipality costs show stickiness or anti-stickiness behaviour after increases or decreases in the stream of their revenues.Design/methodology/approachThe Andersonet al.’s (2003) approach is adapted to the public sector environment by using types of expenses and revenues typical to the local government setting. The data sample consists of 1,852 observations of Greek municipalities for the period 2002-2008.FindingsThe empirical evidence suggests that local government managers adjust resources related to administrative services faster when revenues decrease than when they rise (anti-stickiness cost behaviour). On the contrary, they adjust costs of service provision which are associated with core activities asymmetrically; more quickly for upward than for downward activity changes (cost stickiness behaviour).Research limitations/implicationsWhile prior studies examine the sticky cost phenomenon in the private sector, this study explores this phenomenon in the public sector through a data sample of municipalities. Local governments constitute an appealing and unique setting for the examination of asymmetric cost behaviour due to the existence of a strong political influence, which appears to affect rational economic decision making, and their non-profit character, which prevents them from acting in a business-like manner.Practical implicationsUnderstanding how cost stickiness works inside local understanding how cost stickiness works inside local governments, could lead to an understanding of its implications in periods of cutback measures. Decreases in municipalities’ subsidies and grants as a result of cutbacks in central government expenditures should not be expected to automatically result in symmetric savings in expenditures as corresponding increases in expenditures when revenues used to grow. At the same time, it might be difficult to achieve balanced budgets in municipalities when there is a considerable decrease in revenues, without having to make considerable adjustments to the input values, the output and the mix of services offered by them.Originality/valueThis study contributes to the accounting literature by expanding the understanding of how deliberate decisions influence the asymmetric cost behaviour in local governments, to different cost categories (administrative expenses and cost of service provision) and different revenue categories (grants, tax revenues and revenues from sales of goods and services).