bluuebunny/crossref_metadata_2025_split huggingface dataset:
The SPECTRA Collaboration OMERACT Special Interest Group: Current Research and Future Directions
Authors: Stok Kathryn S. , Finzel Stephanie , Burghardt Andrew J. , Conaghan Philip G. , Barnabe Cheryl 
Published: August 2017

Objective.High-resolution peripheral quantitative computed tomography (HR-pQCT) has the potential to improve radiographic progression determination in clinical trials and longitudinal observational studies. The goal of this work was to describe the current state of research presented at Outcome Measures in Rheumatology (OMERACT) 2016 and ensuing future directions outlined during discussion among attendees.Methods.At OMERACT 2016, SPECTRA (Study grouP for xtrEme-Computed Tomography in Rheumatoid Arthritis) introduced efforts to (1) validate the HR-pQCT according to OMERACT guidelines, focusing on rheumatoid arthritis (RA), and (2) find alternatives for automated joint space width (JSW) analysis. The Special Interest Group (SIG) was presented to patient research partners, physicians/researchers, and SIG leaders followed by a 40-min discussion on future directions.Results.A consensus definition for RA erosion using HR-pQCT was demonstrated through a systematic literature review and a Delphi exercise. Histopathology and perfusion studies were presented that analyzed the true characteristics of cortical breaks in HR-pQCT images, and to provide criterion validity. Results indicate that readers were able to discriminate between erosion and small vascular channels. Moderate reliability (ICC 0.206–0.871) of direct erosion size measures was shown, which improved (> 0.9) only when experienced readers were considered. Quantification of erosion size was presented for scoring, direct measurement, and volumetric approaches, as well as a reliability exercise for direct measurement. Three methods for JSW measurement were compared, all indicating excellent reproducibility with differences at the extremes (i.e., near-zero and joint edge thickness).Conclusion.Initial reports on HR-pQCT are promising; however, to consider its use in clinical trials and longitudinal observational studies, it is imperative to assess the responsiveness of erosion measurement quantification.
Engaging Stakeholders and Promoting Uptake of OMERACT Core Outcome Instrument Sets
Authors: Tunis Sean R. , Maxwell Lara J. , Graham Ian D. , Shea Beverley J. , Beaton Dorcas E. , Bingham Clifton O. , Brooks Peter , Conaghan Philip G. , D’Agostino Maria Antonietta , de Wit Maarten P. , Gossec Laure , March Lyn M. , Simon Lee S. , Singh Jasvinder A. , Strand Vibeke , Wells George A. , Tugwell Peter 
Published: August 2017

Objective.While there has been substantial progress in the development of core outcomes sets, the degree to which these are used by researchers is variable. We convened a special workshop on knowledge translation at the Outcome Measures in Rheumatology (OMERACT) 2016 with 2 main goals. The first focused on the development of a formal knowledge translation framework and the second on promoting uptake of recommended core outcome domain and instrument sets.Methods.We invited all 189 OMERACT 2016 attendees to the workshop; 86 attended, representing patient research partners (n = 15), healthcare providers/clinician researchers (n = 52), industry (n = 4), regulatory agencies (n = 4), and OMERACT fellows (n = 11). Participants were given an introduction to knowledge translation and were asked to propose and discuss recommendations for the OMERACT community to (1) strengthen stakeholder involvement in the core outcome instrument set development process, and (2) promote uptake of core outcome sets with a specific focus on the potential role of post-regulatory decision makers.Results.We developed the novel “OMERACT integrated knowledge translation” framework, which formalizes OMERACT’s knowledge translation strategies. We produced strategies to improve stakeholder engagement throughout the process of core outcome set development and created a list of creative and innovative ways to promote the uptake of OMERACT’s core outcome sets.Conclusion.The guidance provided in this paper is preliminary and is based on the views of the participants. Future work will engage OMERACT groups, “post-regulatory decision makers,” and a broad range of different stakeholders to identify and evaluate the most useful methods and processes, and to revise guidance accordingly.
A Multicenter Nominal Group Study to Rank Outcomes Important to Patients, and Their Representation in Existing Composite Outcome Measures for Psoriatic Arthritis
Authors: Tillett William , Dures Emma , Hewlett Sarah , Helliwell Philip S. , FitzGerald Oliver , Brooke Melanie , James Jana , Lord Jane , Bowen Clive , de Wit Martin , Orbai Ana-Maria , McHugh Neil ,   on behalf of the PROMPT study group
Published: August 2017

Objective.To rank outcomes identified as important to patients with psoriatic arthritis (PsA) and examine their representation in existing composite measures.Methods.Seven nominal group technique (NGT) meetings took place at 4 hospital sites. Two sorting rounds were conducted to generate a shortlist of outcomes followed by a group discussion and final ranking. In the final ranking round, patients were given 15 points each and asked to rank their top 5 outcomes from the shortlist. The totals were summed across the 7 NGT groups and were presented as a percentage of the maximum possible priority score.Results.Thirty-one patients took part: 16 men and 15 women; the mean age was 54 years (range 24–77; SD 12.2), the mean disease duration was 10.3 years (range 1–40; SD 9.2), and mean Health Assessment Questionnaire was 1.15 (range 0–2.63; SD 0.7). The highest-ranked outcomes that patients wished to see from treatment were pain with 93 points (20.0%), fatigue 62 (13.3%), physical fitness 33 (7.1%), halting/slowing damage 32 (6.9%), and quality of life/well-being 29 (6.2%). Reviewing existing composite measures for PsA demonstrated that no single measure adequately identifies all these outcomes.Conclusion.Pain and fatigue were ranked as the outcomes most important to patients receiving treatment for PsA and are not well represented within existing composite measures. Future work will focus on validating composite measures modified to identify outcomes important to patients.
Risk of Obstructive Sleep Apnea and Its Association with Cardiovascular and Noncardiac Vascular Risk in Patients with Rheumatoid Arthritis: A Population-based Study
Authors: Wilton Katelynn M. , Matteson Eric L. , Crowson Cynthia S. 
Published: August 2017

Objective.To define the incidence of obstructive sleep apnea (OSA) in patients with rheumatoid arthritis (RA) and determine whether OSA diagnosis predicts future cardiovascular disease (CVD) and noncardiac vascular events.Methods.Medical information pertaining to RA, OSA, CVD, and vascular diagnoses was extracted from a comprehensive medical record system for a geographically defined population of 813 patients previously diagnosed with RA and 813 age- and sex-matched comparator subjects.Results.The risk for OSA in persons with RA versus comparators was elevated, although not reaching statistical significance (HR 1.32, 95% CI 0.98–1.77; p = 0.07). Patients with RA were more likely to be diagnosed with OSA if they had traditional risk factors for OSA, including male sex, current smoking status, hypertension, diabetes, dyslipidemia, and increased body mass index. Features of RA disease associated with OSA included large joint swelling and joint surgery. Patients with RA with decreased renal function were also at higher risk of OSA. The increased risk of overall CVD among patients with RA who have OSA was similar to the increased CVD risk associated with OSA in the comparator cohort (interaction p = 0.86). OSA diagnosis was associated with an increased risk of both CVD (HR 1.9, 95% CI 1.08–3.27), and cerebrovascular disease (HR 2.4, 95% CI 1.14–5.26) in patients with RA.Conclusion.Patients with RA may be at increased risk of OSA secondary to both traditional and RA-related risk factors. Diagnosis with OSA predicts future CVD in RA and may provide an opportunity for CVD intervention.
Lire les philosophes français dans l’Italie de la seconde moitié du XVIIIe siècle
Authors: Schwarze Sabine 
Published: August 2017

Au cours du XVIIIe siècle, la vocation de la langue française à « l'universalité », telle qu'elle est proclamée pompeusement par Rivarol en 1784 dans sa célèbre dissertation, est due surtout au prestige des œuvres—littéraires, philosophiques, scientifiques—qui s'expriment en cette langue. Le Siècle des lumières converse et écrit en français, même si on n'est pas francophile. Malgré une large diffusion du français en Italie, les grands textes français du siècle posent des problèmes de divers genres à la lecture: problèmes de diffusion ou bien de marché, provoqués par une politique restrictive de l'achat et de l'édition; problèmes linguistiques, la compétence linguistique des Italiens ne permettant pas la compréhension effective de textes philosophiques et scientifiques en français; problèmes de traduction, la langue italienne n'ayant pas les mêmes capacités pour rendre soit le lexique soit la syntaxe du français avec la même précision et clarté. À la motivation idéologique pour une étude des grands auteurs des Lumières européennes s'adjoint, dans le cas spécifique des Lumières françaises, l'héritage d'un fort sentiment de « concurrence » linguistique et culturel par rapport à la France. « Lire les Français » signifie alors jusqu'au XIXe siècle toujours confrontation linguistique, comparaison de deux systèmes linguistiques dont l'histoire dès le début est aussi une histoire d'influence réciproque, et au niveau métalinguistique d'un débat continuel
Représentations picturales du livre et de la lecture dans l’Angleterre du XVIIIe siècle : quel iconotexte ?
Authors: Détis Élisabeth 
Published: August 2017

La lecture se pratiquait selon des modes multiples (silencieuse, à la famille rassemblée...) et les sujets d’intérêt étaient extrêmement divers (Shakespeare, Milton, Pope, récits de voyage, biographies, essais économiques, fiction...). En peinture, la représentation d’eux-mêmes, de leurs maisons, de leurs chevaux et de leurs familles était le principal sujet d’intérêt des commanditaires de tableaux. Héritières des peintures hollandaises où figure en bonne place un livre ouvert ou une lettre, de nombreuses toiles anglaises mettent en scène la « textualité en peinture » (« textuality in painting ») selon les mots de W. J. T. Mitchell. Le corpus retenu pour cet article est d’une douzaine d’œuvres. L’étude des représentations picturales du livre et de la lecture obéit à des contraintes particulières qui tiennent essentiellement à la nature particulière de l’objet décrit. Représenter en effet un livre dans une image c’est faire d’un texte une image : c’est elle qui est vue et non le texte qui est lu directement, mais le texte est à la fois présupposé (on sait ce que contient un livre : des mots) et donné à lire (au modèle). L’on part de l’image et l’on aboutit au texte, voire au contexte : qu’est ce que cette image dit de l’écriture, de la lecture à l’époque ? Qu’est ce qu’elle reflète des goûts du personnage ? Mais l’on n’a pas pour autant quitté l’image : quel est le mode de représentation picturale de ces activités de lecture et de ces objets-supports, les livres ? L’on revient enfin à l’image-texte : l’écriture qui a le texte comme résultat et la lecture dont il est le support sont-elles des activités humaines qui donnent lieu à une représentation fondamentalement différente que ne le serait par exemple celle du sport ou des loisirs. À quel genre d’iconotexte le spectateur-lecteur est-il confronté quand le livre est représenté par l’image, quand la peinture parle et que la poésie se tait (« Pictura loquens, poesis tacens ») ?
La relation auteur-lecteur dans les paratextes de la fiction des Lumières : une logique de la contrainte
Authors: Arends Isabelle Brouard 
Published: August 2017

L’étude interroge en particulier deux romans épistolaires qui ont marqué les esprits du temps, La Nouvelle Héloïse et Adèle et Théodore de Mme de Genlis (1782). La question posée est la suivante : en quoi La Nouvelle Héloïse et son paratexte, en particulier, son Entretien sur les romans entre l’éditeur et un homme de lettres, peuvent être considérés comme une étape décisive dans l’élaboration de la relation auteur-lecteur, peut-on préciser auteur-lectrice ? Julie, est-elle emblématique des rapports de la femme au savoir, tels que la fiction les a construits à cette époque ? En quoi le roman de Mme de Genlis qui est précédé d’une préface, dans les éditions postérieures à la première édition, dans laquelle il est fait mention et de la Nouvelle Héloïse et d’Émile et qui reprend les mêmes configurations décelables dans l’Entretien sur les romans, en quoi donc ce roman entérine une démarche d’adresse au lecteur, ou plutôt, d’adresse à la lectrice ?
Reliable Earlier and Causative Biomarker in newly Diagnosed Hypothyroid Cases—Vitamin D: A Case–control Study
Authors: Prabha AG Thivyah 
Published: August 2017

ABSTRACTBackgroundIn Indian population there are 42 million people suffering from hypothyroidism. Hence, even though thyroid-stimulating hormone (TSH) has been used as the diagnostic marker of hypothyroidism, there arises a need to evaluate an earlier and a causative marker for hypothyroidism and thus it could be a better predictor of the disease in the earlier stages only.Aims and objectivesThe aim of the study is to identify a reliable earlier and one of the causative biomarkers of hypothyroidism.Materials and methodsThis study was conducted in 200 cases of newly diagnosed hypothyroidism and 200 controls of healthy individuals. Vitamin D, intact parathyroid hormone, TSH, triiodothyronine, thyroxine, and calcium were measured.ResultsIt was observed that vitamin D was significantly decreased in hypothyroid cases. There was a negative correlation between vitamin D and TSH.ConclusionVitamin D being one of the causative factors in thyroid disorders should be included as a routine parameter of analysis in hypothyroid cases and supplementation of vitamin D also to be initiated by the clinicians to avoid the progression to overt hypothyroidism in the newly diagnosed cases.How to cite this articlePrabha AGT. Reliable Earlier and Causative Biomarker in newly Diagnosed Hypothyroid Cases‗Vitamin D: A Case–control Study. Indian J Med Biochem 2017;21(1):54-57.
Bisalbuminemia in an African Male with Sickle Cell Disease
Authors: Chakravarthy Srinivas N , Durairaj Mathivanan 
Published: August 2017

ABSTRACT
Bisalbuminemia is a rare condition characterized by abnormal electrophoretic pattern of serum albumin. There are two types of bisalbuminemia – hereditary and acquired. The acquired type has been reported in chronic renal diseases, pancreatitis, and in patients using beta-lactam antibiotics. The aim of this case report is to discuss the clinical significance of bisalbuminemia in a 58-year-old African male with sickle cell anemia.

How to cite this article
Chakravarthy SN, Ramanathan S, Menon S, Durairaj M. Bisalbuminemia in an African Male with Sickle Cell Disease. Indian J Med Biochem 2017;21(1):69-71.
Corta-me: Ensaio sobre Tradução
Authors: Protásio Luís Fernando 
Published: August 2017

http://dx.doi.org/10.5007/1980-4237.2014n16p118Como o ensaio de um espetáculo cuja estreia está, ainda, por vir, este exercício acompanha, em estilo experimental, a cena da tradução da escritora e tradutora canadense radicada em Paris Nancy Huston. O objetivo é apresentar a genealogia de uma ética que, ao cortar a lógica da repetição alienadora de determinado atributo (o “outro”, a “letra”, a “diferença”...), eleva o intervalo do desejo, transformando-se ela mesma numa tarefa sempre – ainda − por vir.ABSTRACTResembling the rehearsal of a spectacle whose debut is yet to come, this essay follows, in an experimental style, the translation scene of Paris-based Canadian author and translator Nancy Huston. The aim is to exhibit the foundation of an ethics which, by cutting up the logic of an alienating repetition of a given attribute (the so-called “other”, “letter”, “difference”…), enhances the interval of the desire, becoming itself a task always [yet] to come.Keywords: translation and ethics; selftranslation; becoming.
A Tradução no dia a dia. Um glossário pessoal inglês-português, de Jorge Rogério Penha Rodrigues
Authors: Perrotti-Garcia Ana Júlia 
Published: August 2017

Jorge Rodrigues é um tradutor bastante dedicado, e pelo que costuma divulgar, muitas vezes passa noites traduzindo, para entregar seus trabalhos sempre dentro do prazo e com qualidade. O autor tem diversas certificações internacionais, entre elas Proficiency in English pelas universidades de Michigan (EUA) e Cambridge (Reino Unido), além do International Legal English Certificate também pela universidade britânica. Além do inglês, Jorge atua como tradutor de francês, e tem espanhol e italiano fluentes. Jorge tem o título de Tradutor Público e Intérprete Comercial (TPIC, ou, como se diz popularmente, “tradutor juramentado”) e Perito do Tribunal de Justiça do Estado de Sergipe.
Is de filosofie te links?
Authors: De Block Andreas , Lemeire Olivier 
Published: August 2017

Abstract

Is Philosophy too Left-wing?

Ideological diversity has been on the research agenda in the social sciences for a couple of years. Yet in philosophy, the topic has not attracted much interest. This article tries to start filling this gap. We discuss a number of possible causes for the underrepresentation of right-wing and conservative philosophers in the academic profession. We also argue why this should be an important concern, not only morally, but also and primarily epistemically. Lastly, we explore whether the situation in philosophy is more problematic than the situation in other fields, and what kind of ideological diversity would be desirable for academic philosophy.
Sophie de Grouchy, de traditie(s) van de twee vrijheden en de missende moeder(s) van het liberalisme1
Authors: Schliesser Eric 
Published: August 2017

Abstract

Sophie de Grouchy: The Tradition(s) of Two Liberties and the Missing Mother(s) of Liberalism

In this paper, I treat Sophie de Grouchy as an important contributor to liberal reflection on the famous distinction between two kinds of liberty. I place her in the intellectual context of Adam Smith and Jean-Jacques Rousseau, and show it is likely that Benjamin Constant was familiar with her work. Along the way, by engaging with Isaiah Berlin and with Jason Stanley and Vesla Weaver, I make some suggestions on the nature of an intellectual tradition worth having.
The Implementation of Differentiated Instruction in English Language Learning to Students with Dyslexia in A’ Senior Class (A1) in an English Language Center: Action Research
Authors: Nikolaou Xanthoula Evangelia , Zafiri Dr.Makrina , Pliogou Dr.Vassiliki 
Published: August 2017

The purpose of this study is to investigate the implementation of differentiated instruction as a means of teaching English tο children with dyslexia (A’ senior level) at a private English Language Center, located in the suburbs of the city of Thessaloniki, in Greece. For the present action research, three ten-year-old male students participated in ten lessons designed according to the principles of differentiated instruction. The lessons took place once a week for one hour and they lasted for two and half months. The methodology used for this small scale search, was qualitative, as semi-structured interviews were applied to both the students and their mothers. According to the findings of this small scale action research study, the method of differentiated teaching is an effective method of teaching a foreign language to students with dyslexia.
The Caprice of Being: Αἰών and Φύσις in Merleau-Ponty, Heraclitus, and Deleuze
Authors: Whitmoyer Keith 
Published: August 2017

ABSTRACT
This article examines Merleau-Ponty's proposal to articulate a new ontology by returning to the pre-Socratic idea of φύσις and following a reference he makes to Heraclitus's fragment B52. Interestingly, this fragment refers to αἰών, “eternity,” as a child at play. Against the Laplacean idea that nature is the necessary and calculable unfolding of causes and effects, and anticipating what Deleuze will outline in The Logic of Sense, Merleau-Ponty suggests that φύσις—understood in terms of the temporal dis-order of αἰών rather than the Aristotelian order of χρόνος—is an ideal game without rules, what Nietzsche describes as an “innocent caprice.”
The Problem of Forgiveness: Jankélévitch, Deleuze, and Spinoza
Authors: Ford Russell 
Published: August 2017

ABSTRACT
The problem of forgiveness may rightly be regarded as a perennial philosophical problem. Introducing his 1973 essay “Forgiveness,” Aurel Kolnai writes that, logically, forgiveness seems to be either “unjustified or pointless.” The logical and ethical problem of forgiveness acquired distinctive urgency in the 1960s when statutes of limitations on Nazi war crimes were set to expire. In the resulting debates, the ethicist Vladimir Jankélévitch occupies a central place. In his book Forgiveness and elsewhere, Jankélévitch singles out Spinoza as a philosopher with a particularly inadequate account of forgiveness. This article contextualizes Jankélévitch's argument and argues that Spinoza's conception of evil and forgiveness is essential for understanding why Jankélévitch himself cannot consistently account for his refusal to advocate forgiving the German people after the Holocaust. Drawing on Sylvain Zac's account of forgiveness in Spinoza, as well as Deleuze's account of the problem of evil as it arises in Spinoza's correspondence with Blyenburgh, this article argues that Spinoza offers an account of forgiveness that makes sense of what is ethically required in the face of what Carse and Tirrell call “world-shattering” wrongs such as the Holocaust.
Habit and Freedom in Merleau-Ponty and Ricœur
Authors: Čapek Jakub 
Published: August 2017

ABSTRACT
Philosophical debates on habit often emphasize its ambivalent character: once habitualized, voluntary activity becomes natural. Consequently, the ambiguity of habit is the ambiguity of freedom and nature. This view was recently criticized by Claude Romano for its lack of conceptual clarity. Focusing on the phenomenology of habit as developed by Ricœur and Merleau-Ponty, and in response to Romano, this article shows not only that habit cannot be stripped of its ambiguity but also how this ambiguity affects our understanding of subject and freedom.
Critical Theory in the Age of Knowledge Capitalism: Elusive Exploitation, Affects, and New Political Economies
Authors: Thiem Yannik 
Published: August 2017

ABSTRACT
After decades of largely avoiding engagements with political economy, discussions of speculative capitalism, neoliberalism, and the information society have become central again to critical theory. However, often when information capitalism is discussed, the more radical political potentials of the critiques remain subdued because the analyses of emergent patterns of knowledge creation and dissemination are largely understood in the context of (a) traditional categories of work and (b) political progress by increased communication and participation. This article argues that instead a focus on immaterial labor helps to grasp the constitutive difficulties in grappling with the political implications of this new economic paradigm. To make its case, the article will offer a rereading of Marx's commodity fetishism as practices of translation, transposition, and metamorphosis and elaborate how we might come to grips with the current political impasses and resist the desire for nostalgic returns to a time before speculative knowledge capitalism.