bluuebunny/crossref_metadata_2025_split huggingface dataset:
Raman spectroscopic studies across the ferroelectric transition in cobalt substituted dimethyl amine manganese formate
Authors: Premila M. , Bharathi A. , Rajaraman R. , Hussain Shamima , Babu P. D. , Sundar C. S. , Amarendra G. 
Published: January 2018

AbstractTemperature‐dependent Raman studies, across the ferroelectric transition, Tc, in the metal organic framework material, [(CH3)2NH2][Mn(HCOO)3]—DMMn, and its cobalt (Co) doped analogues have been carried out to look for the changes in the lattice and intramolecular modes associated with the orientational ordering of the central dimethyl ammonium cation (DMA+) driven by the hydrogen‐bonded interaction between the DMA cation and the formate anion. A systematic decrease of the transition temperature with increased Co doping has been observed that correlates with results of specific heat measurements. The low‐wavenumber librational mode of the DMA cation shows a dramatic softening and narrowing of line width, across the transition, providing direct evidence of the slowing down of the rotation of the DMA cation associated with the orientational ordering. The evolution with temperature of the N‐H stretch modes of the DMA cation suggests that invoking the hydrogen‐bonding interactions alone is not enough to understand the observed decrease in the ferroelectric transition with Co doping in DMMn. A subtle interplay between the framework flexibility, size/charge of the metal cation, and the hydrogen‐bonding tendency finally decides the transition temperature in these materials.
Surface‐enhanced Raman spectroscopy solution and solid substrates with built‐in calibration for quantitative applications
Authors: Wu Si‐Rong , Tian Xiang‐Dong , Liu Si‐Ying , Zhang Yun , Li Jian‐Feng 
Published: January 2018

AbstractQuantitative analysis is a significant step forward for expanding the applications of surface‐enhanced Raman spectroscopy (SERS) in various fields. The reproducibility of the SERS measurement relies on the quality of the SERS substrates. Therefore, high enhancement SERS substrate with high uniformity and reproducibility is highly demanded for quantitative analysis. However, it remains a challenge to realize all the requirements of the SERS substrate. Here, we report 2 types (solution and solid) of SERS substrates with built‐in calibration for quantitative analysis. To prepare the substrates, high monodisperse Au@Ag nanocuboids (NCs) with internal standards trapped between the Au core and Ag shell are synthesized through the Au‐nanorod‐mediated method. It is demonstrated that at least 2 types of SERS tags can be trapped to synthesize the core‐internal standard‐shell (CISS) NCs. The SERS quantitative ability of the CISS NCs in solution is proved by detecting Rhodamine 6G, where a good linear relationship in a wide concentration range from 3 × 10−11 M to 1 × 10−8 M is achieved through the built‐in calibration. Besides the solution‐SERS substrate, CISS NCs are self‐assembled at the air–water interface to form uniform monolayer as the solid SERS substrate. SERS mapping reveals that the uniformity of the enhancement is improved through the built‐in calibration. The quantitative detection of concentration of Rhodamine 6G is achieved through the calibrated SERS mapping of the substrate. The internal and external enhancement factor calculation of the 2 types of SERS substrates indicates the promising method to further improve the reliability of the SERS analysis.
Contrast‐Enhanced Ultrasonography Versus Contrast‐Enhanced Computed Tomography for Assessment of Residual Tumor From Hepatocellular Carcinoma Treated With Transarterial Chemoembolization: A Meta‐analysis
Authors: Zhong Junlin , Su Zhongzhen , Zhang Yanling , Zhang Hui , Lin Peijie , Tang Xixiang , Zheng Rongqin 
Published: January 2018

ObjectivesThis study reviewed the literature to directly evaluate the diagnostic performance of contrast‐enhanced ultrasonography (CEUS) versus contrast‐enhanced computed tomography (CECT) for assessing residual tumors of hepatocellular carcinoma treated with transarterial chemoembolization.MethodsPubMed, Embase, the Cochrane Library, and the China National Knowledge Infrastructure were searched through April 30, 2017. The pooled sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio, and summary receiver operating characteristic curve were calculated and compared to examine the diagnostic performance of CEUS versus CECT.ResultsA total of 11 studies, including 421 patients and 491 nodules were analyzed. The pooled diagnostic performances of CEUS versus CECT were as follows: (1) sensitivity (95% confidence interval), 0.97 (0.95–0.99) versus 0.72 (0.67–0.76); (2) specificity, 0.86 (0.74–0.94) versus 0.99 (0.95–1.00); (3) positive predictive value, 0.97 (0.95–0.99) versus 1.00 (0.98–1.00); (4) negative predictive value, 0.90 (0.83–0.95) versus 0.51 (0.44–0.58); (5) positive likelihood ratio, 7.79 (4.73–12.82) versus 12.50 (5.74–27.20); (6) negative likelihood ratio, 0.05 (0.03–0.09) versus 0.35 (0.26–0.48); (7) diagnostic odds ratio, 150.56 (57.03–397.49) versus 35.54 (14.89–84.83); and (8) area under the summary receiver operating characteristic curve, 0.9875 versus 0.9239. The sensitivity and negative predictive value of CEUS were significantly higher than those of CECT (both P < .001). The specificity and positive predictive value of CECT were significantly higher than those of CEUS (both P < .05).ConclusionsContrast‐enhanced US, with better sensitivity and negative predictive value versus CECT, was an effective method for exclusion of residual tumors after transarterial chemoembolization. Contrast‐enhanced CT, with higher specificity than CEUS, is a valid approach for identifying residual tumors.
Particulate polyphosphate and alkaline phosphatase activity across a latitudinal transect in the tropical Indian Ocean
Authors: Martin Patrick , Lauro Federico M. , Sarkar Amit , Goodkin Nathalie , Prakash Satya , Vinayachandran P. N. 
Published: January 2018

AbstractPolyphosphate (polyP) is an essential chemical constituent of microbial cells, and is hypothesized to play important roles in the marine biogeochemistry of phosphorus. However, polyP has only rarely been measured in the oceans. Here, we present data on the distribution of polyP across a latitudinal transect in the tropical Indian Ocean. PolyP concentrations (quantified as molar equivalents of a synthetic polyP standard) and ratios of polyP to total particulate phosphorus (TPP) along the transect ranged between 3–7 nmol eq. L−1 (polyP concentration) and 0.2–0.4 nmol eq. nmol−1 (polyP : TPP ratio), which is very similar to values reported from the North Pacific Subtropical Gyre. Yet unlike in the North Pacific, soluble reactive phosphorus was depleted to low concentrations (≤ 0.03 μmol L−1), and alkaline phosphatase activity was relatively high (1–4 nmol P L−1 h−1) along our cruise track. We attribute these results to the unique seasonal changes in iron and macronutrient supply in the Indian Ocean, which are caused by the monsoonal reversal in ocean currents. PolyP concentrations and polyP : TPP ratios decreased sharply with depth down to 150 m, suggesting that polyP was preferentially recycled relative to TPP, unlike in the North Pacific Subtropical Gyre. We hypothesize that alkaline phosphatase exerts a significant control over marine polyP biogeochemistry.
Investigation of metallic adapter sleeves for high throughput dilatometry on spherical micro samples
Authors: Cramer L. , Saddei P. , Surm H. , Steinbacher M. , Zoch H.W. 
Published: January 2018

AbstractThe rods of an available quenching dilatometer are modified for investigations on spherical micro samples (Ø = 1 mm) via metallic adapter sleeves. The experiments can be seen as preliminary tests for a planned high throughput dilatometer, in which adapters are needed as well. Sleeve geometry and materials are varied in the trials to reproduce the transformation of the micro samples using standardized temperature measuring techniques. Sleeves made out of molybdenum produce the best results because molybdenum has a low and nearly constant thermal expansion up to 700 °C. Sleeves of nickel alloy 36 (Invar) or of an austenitic steel (1.4841) do not produce satisfying results. Thermally induced phase transformations of balls of 100Cr6 and X46Cr13 are successfully measured with the existing dilatometer for common macro samples. First the martensitic transformation is investigated, later the process is verified by the isothermal bainitic transformation of 100Cr6.
Friction and wear properties of polyphenyl ester and graphite filler in the carbon fibre‐reinforced ultra‐high‐molecular‐weight polyethylene composites
Authors: Wang Z. , Guo L. , Gao P. , Xu S. , Liu X. , Liu Y. , Tong J. 
Published: January 2018

AbstractUltra‐high‐molecular‐weight polyethylene (UHMWPE) reinforced with carbon fibre (CF) underwent an enhancement of heat and wear resistant with the addition of polyphenyl ester (POB) and graphite, respectively. The effect of graphite content on the tribological properties of the composites was studied. The wear surface was examined using scanning electron microscope (SEM). The results of the sliding wear tests showed that with graphite loading, wear resistance increased and the coefficient of friction was much more stable. In addition, graphite improved the tribological properties of the composite. Hardness, impact strengths and thermal stability of the composites were enhanced. With increased load, the wear rate of the ultra‐high‐molecular‐weight polyethylene+carbon fibre+polyphenyl ester+10 % graphite composite tended to increase, whereas the coefficient of friction decreased. The adherence and plastic deformation were dominant wear mechanisms for the ultra‐high‐molecular‐weight polyethylene+carbon fibre+polyphenyl ester+graphite composites. The formation of a thin and uniform transfer film was observed.
Novel FOXL2 mutations cause blepharophimosis‐ptosis‐epicanthus inversus syndrome with premature ovarian insufficiency
Authors: Yang Xiao‐Wen , He Wen‐Bin , Gong Fei , Li Wen , Li Xiu‐Rong , Zhong Chang‐Gao , Lu Guang‐Xiu , Lin Ge , Du Juan , Tan Yue‐Qiu 
Published: January 2018

AbstractBackgroundBlepharophimosis‐ptosis‐epicanthus inversus syndrome (BPES) is a malformation of the eyelids. Forkhead Box L2 (FOXL2) is the only gene known to be associated with BPES.MethodsWe identified two Han Chinese BPES families with premature ovarian insufficiency (POI). Sanger sequencing and in vitro functional analysis were performed to identify the genetic cause.ResultsSanger sequencing identified two novel mutations (c.462_468del, c.988_989insG) in FOXL2, one in each family. The in vitro functional analysis confirmed that both novel mutations were associated with impaired transactivation of downstream genes. Specifically, the single‐base insertion, c.988_989insG, led to subcellular mislocalization and aggregation of the encoded protein, which validated the hypothesis that the two novel FOXL2 mutations are deleterious and associated with POI in the two BPES families.ConclusionThe novel mutations identified in the present study will enhance the present knowledge of the mutation spectrum of FOXL2. The in vitro experiments provide further insights into the molecular mechanism by which the two new variants mediate disease pathogenesis and may contribute to elucidating the genotype‐phenotype correlation between the two novel FOXL2 mutations and POI.
Masseteric cooptation and crossfacial nerve grafting: Is it still applicable 22 months after the onset of facial palsy?
Authors: Bianchi B. , Varazzani A. , Pedrazzi G. , Poddi V. , Ferrari S. , Brevi B. , Ferri A. 
Published: January 2018

AbstractBackgroundEighteen months is usually considered the cutoff time within which recovery of the mimic muscle remains possible using facial nerve cooptation. Few reports on the use of cooptation after this interval have appeared. Purpose of this study is to investigate the feasibility of this procedure also after 22 months.MethodsSix patients treated via crossfacial nerve grafting between healthy and paralyzed middle and middle‐upper facial nerve branches and masseteric cooptation of the main trunk of the paralyzed facial nerve between 20 and 24 months after the onset of palsy were analyzed. Population consisted of two males and four females ages 8‐42 years (mean 24 years). Facial palsy developed after acoustic neuroma resection in three patients, after the removal of a cerebellopontine angle astrocytoma in one, and as a consequence of Bell's palsy or cerebral hemorrhage in the other two (one each). House‐Brackman and Sunnybrook clinical evaluation systems and FDI questionnaire were used to assess results.ResultsHouse‐Brackman scores changed from VI before the operation for all patients to II for two patients and III for four patients. Sunnybrook scores were 0‐10 before the operation, but 62‐84 at the last visit. Mean FDI scores moved from 24 to 38.5 meaning a statistical high significant improvement (P < .01).ConclusionsMasseteric/crossfacial nerve grafting is feasible for patients with palsies 20‐24 months in duration, affording satisfactory functional and esthetic results and a dramatic improvement in quality of life.
Experiences of a patient‐initiated self‐monitoring service in inflammatory arthritis: A qualitative exploration
Authors: McBain Hayley , Newman Stanton , Shipley Michael , Olaleye Abigail , Moore Samantha 
Published: January 2018

AbstractObjectivesThe aim of the present study was to explore patients' experience of a patient‐initiated self‐monitoring service for people with rheumatoid or psoriatic arthritis who are on methotrexate.MethodsThe study took the form of qualitative semi‐structured interviews, embedded within a randomized controlled trial. Twelve participants who were randomly assigned to the intervention arm were interviewed. Interviews digitally, transcribed verbatim and analysed using inductive thematic analysis. The study received full National Health Service ethics approval from Camden and Islington Community Local Research Ethics Committee (Ref. 09/H0722/91).ResultsAnalysis revealed five key themes. Participants described usual care as burdensome and an inefficient use of time, particularly those in employment. Being able to self‐monitor and initiate their own care increased patients' knowledge about their illness and its treatment, and enabled them to gain a sense of control and ownership over their arthritis. They appreciated the personalized nature of the new service, which allowed them to be seen at a time and by a method more appropriate to their needs. There were, however, some concerns about fidelity to the service protocol, confusion about the lack of consistency between symptoms and laboratory results, and anxiety about self‐monitoring.ConclusionsOverall, participants were positive about the new service, in comparison with usual care, valuing its tailored approach and empowering effects. Further work is needed to ensure adherence to the service protocol and address anxieties around self‐monitoring prior to any widespread implementation of the service.
Motor unit number index and neurophysiological index as candidate biomarkers of presymptomatic motor neuron loss in amyotrophic lateral sclerosis
Authors: Escorcio‐Bezerra Marcio Luiz , Abrahao Agessandro , Nunes Karlo Faria , De Oliveira Braga Nadia Iandoli , Oliveira Acary Souza Bulle , Zinman Lorne , Manzano Gilberto Mastrocola 
Published: January 2018

ABSTRACTIntroduction: Our objective was to determine the utility of motor unit number index (MUNIX) and neurophysiological index (NI) as surrogate biomarkers of disease progression in limbs without clinical signs of lower motor neuron (LMN) involvement from patients with slowly progressive amyotrophic lateral sclerosis (ALS).Methods: Patients with slowly progressive ALS and at least 1 clinically unaffected limb were prospectively enrolled. Clinical signs of LMN loss and results from hand‐held dynamometer (HHD), revised ALS Functional Rating Scale (ALSFRS‐R), mean‐MUNIX (from 3 different muscles), and NI were longitudinally recorded.Results: Eighteen patients with 43 presymptomatic muscles were evaluated. Twenty‐seven muscles remained clinically unaffected during study, with stable ALSFRS‐R subscores and HHD measures. However, a significant decline in mean‐MUNIX and NI was detected.Discussion: Mean‐MUNIX and NI were more sensitive than clinical measures at detecting LMN loss in presymptomatic limbs from patients with slowly progressive ALS. Therefore, these electrophysiological biomarkers should be included in early study phases as meaningful outcome measures.Muscle Nerve58: 204–212, 2018
Eigenvalues and eigenvectors of banded Toeplitz matrices and the related symbols
Authors: Ekström S.‐E. , Serra‐Capizzano S. 
Published: January 2018

SummaryIt is known that for a tridiagonal Toeplitz matrix, having on the main diagonal the constant a0 and on the two first off‐diagonals the constants a1(lower) and a−1(upper), which are all complex values, there exist closed form formulas, giving the eigenvalues of the matrix and a set of associated eigenvectors. For example, for the 1D discrete Laplacian, this triple is (a0,a1,a−1)=(2,−1,−1). In the first part of this article, we consider a tridiagonal Toeplitz matrix of the same form (a0,aω,a−ω), but where the two off‐diagonals are positioned ω steps from the main diagonal instead of only one. We show that its eigenvalues and eigenvectors can also be identified in closed form and that interesting connections with the standard Toeplitz symbol are identified. Furthermore, as numerical evidences clearly suggest, it turns out that the eigenvalue behavior of a general banded symmetric Toeplitz matrix with real entries can be described qualitatively in terms of the symmetrically sparse tridiagonal case with real a0, aω=a−ω, ω=2,3,…, and also quantitatively in terms of those having monotone symbols. A discussion on the use of such results and on possible extensions complements the paper.
Scalable hierarchical PDE sampler for generating spatially correlated random fields using nonmatching meshes
Authors: Osborn Sarah , Zulian Patrick , Benson Thomas , Villa Umberto , Krause Rolf , Vassilevski Panayot S. 
Published: January 2018

SummaryThis work describes a domain embedding technique between two nonmatching meshes used for generating realizations of spatially correlated random fields with applications to large‐scale sampling‐based uncertainty quantification. The goal is to apply the multilevel Monte Carlo (MLMC) method for the quantification of output uncertainties of PDEs with random input coefficients on general and unstructured computational domains. We propose a highly scalable, hierarchical sampling method to generate realizations of a Gaussian random field on a given unstructured mesh by solving a reaction–diffusion PDE with a stochastic right‐hand side. The stochastic PDE is discretized using the mixed finite element method on an embedded domain with a structured mesh, and then, the solution is projected onto the unstructured mesh. This work describes implementation details on how to efficiently transfer data from the structured and unstructured meshes at coarse levels, assuming that this can be done efficiently on the finest level. We investigate the efficiency and parallel scalability of the technique for the scalable generation of Gaussian random fields in three dimensions. An application of the MLMC method is presented for quantifying uncertainties of subsurface flow problems. We demonstrate the scalability of the sampling method with nonmatching mesh embedding, coupled with a parallel forward model problem solver, for large‐scale 3D MLMC simulations with up to 1.9·109 unknowns.
Retracted: ‘A cross‐sectional qualitative analysis of the seeming split between nursing and midwifery professions in Ghana and the way forward’ by Michael Wombeogo
Authors: Wombeogo Michael 
Published: January 2018

The above article in Nursing Open, published online on 29th January, 2018 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Dr. Roger Watson and John Wiley & Sons Ltd. The retraction has been agreed due to unattributed overlap with other published material. The Editor‐in‐Chief carried out an investigation and concluded that there was no intention to deceive by the author.REFERENCEWombeogo, M. (2018). A cross‐sectional qualitative analysis of the seeming split between nursing and midwifery professions in Ghana and the way forward. Nursing Open, 00, 1–5. https://doi.org/10.1002/nop2.125
Dye Displacement Assay for Saccharides using Benzoxaborole Hydrogels
Authors: Lampard Emma V. , Sedgwick Adam C. , Sombuttan Thitima , Williams George T. , Wannalerse Boontana , Jenkins A. Toby A. , Bull Steven D. , James Tony D. 
Published: January 2018

AbstractDye displacement assays are a simple but effective method to determine the concentration of target analytes. Previously, we have shown that phenylboronic acid pinacol ester hydrogels (borogels) can be used to develop a boronic acid–Alizarin red S dye displacement assay for the determination of fructose (orange to red). In this work, benzoxaborole hydrogels (BOBgels) were developed, and these BOBgels demonstrated an enhanced apparent binding affinity towards monosaccharides, in particular towards glucose.
Response to the BRAF/MEK inhibitors dabrafenib/trametinib in an adolescent with a BRAF V600E mutated anaplastic ganglioglioma intolerant to vemurafenib
Authors: Marks Asher M. , Bindra Ranjit S. , DiLuna Michael L. , Huttner Anita , Jairam Vikram , Kahle Kristopher T. , Kieran Mark W. 
Published: January 2018

AbstractEfficacy of BRAF V600E targeted therapies in brain tumors harboring the mutation has been shown in several case reports and is currently being studied in larger clinical trials. Monotherapy with vemurafenib has been associated with significant side effects, including rashes, papillomas, and squamous cell carcinomas. Here we describe an adolescent female with anaplastic ganglioglioma and significant skin reaction to vemurafenib with subsequent tumor response and tolerance to the BRAF/MEK inhibitor combination of dabrafenib and trametinib without recurrence of previous reaction.