bluuebunny/crossref_metadata_2025_split huggingface dataset:
Who Art In Heaven
Authors: Steuart R. H. J. 
Published: September 2024

‘Who art in Heaven.’ This is a puzzling expres- sion. Where is Heaven, and how can God be fixed in Heaven or anywhere at all? In old days people really did think that there was a hard-and-fast place in the universe above us. They thought that the sky was a solid dome, a firmament, and that there was water above and below, and that the water poised above the dome of the sky was allowed to descend. They used the expressions of their day. It is the natural instinct in man to look up to God as if he were poised actually, physically above us.When we talk of Heaven, the Church does not mean us to believe that God is enthroned in one particular place above. God is everywhere in a sense that cannot be described in terms of our experience.
Padre Pio Da Pietrelcina
Authors: Hollings Michael 
Published: September 2024

Padre Pio da Pietrelcina is not widely known, in England, and the occasional references to him give the wrong emphasis. If he is mentioned, it is usually as ‘that supposed stigmatist somewhere in Italy'; so that the immediate impression is adverse, even damning. Now that is as it should be. The masters of the spiritual life cry out to us: Beware of hysteria! Avoid strange phenomena! Live by Faith!Early in the morning, before five, the sacristy door at St Giovanni Rotondo, near Foggia, opens and Padre Pio comes in to say Mass. He comes in slowly, almost shuffling. A tired face, the beard tinged with grey; a large nose, slightly splayed-out from suuff-taking; eyes that pierce and laugh, while the mouth and cheeks follow the eyes; a face serene, radiant, simple. Quite stout, quite short—you see such figures every day on the roads of Italian towns and countryside—the Cappucini.
A knowledge transfer method for human-robot collaborative disassembly of end-of-life power batteries based on augmented reality
Authors: Li Jie , Duan Liangliang , Qu Weibin , Zheng Hangbin 
Published: September 2024

Abstract
The disassembly of power batteries poses significant challenges due to their complex sources, diverse types, variations in design and manufacturing processes, and diverse service conditions. Human memory capacity and robot cognitive and understanding capabilities are limited when faced with different dismantling tasks for end-of-life power batteries. Insufficient human-computer interaction capabilities greatly hinder the efficiency of human-robot collaboration (HRC) operations. The existing HRC relies heavily on the experience of operators, while the existing disassembly system fails to update new disassembly strategies in real time when facing new battery varieties. Therefore, this paper proposes an augmented reality-assisted human-robot collaboration (AR-HRC) power battery dismantling system based on transfer learning. It consists of three modules: AR-HRC knowledge modeling, dismantling subgraph similarity assessment, and strategy transfer update. The AR-HRC knowledge modeling module aims to establish an intelligent mapping from tasks to collaborative strategies based on part features. Based on the evaluation of task similarity, the mobility assessment model divides subtasks into similar and dissimilar classes. For similar subtasks, the original dismantling strategy can be applied to the current task. However, for different subtasks, operators can issue instructions to the AR-HRC system through the human-computer interaction function of AR and develop new collaborative strategies based on actual conditions. Finally, a case study of power battery dismantling is conducted, and the results show that compared to traditional pre-programmed assembly, this system can improve dismantling efficiency and reduce cognitive burden.
Medication management and electrocardiogram screening in children with attention deficit hyperactivity disorder
Authors: Pentony Michaela , Ali Zainab , Moore Kieran , McNicholas Fiona , James Adam 
Published: September 2024

AbstractBackground:To quantify the proportion of referrals sent to Crumlin Cardiology Department for cardiac screening prior to commencement or modifying attention deficit hyperactivity disorder medication and assess the number detected with a clinically significant abnormality.Methods:A prospective audit was performed over a 6-month period, from November 2021 to April 2022 inclusive. Referrals sent via outpatient department triage letters, electrocardiogram dept. email, and walk-in electrocardiogram service were screened for those pertaining to commencing or modifying medication for children with attention deficit hyperactivity disorder. Each referral was coded against National Institute for Health and Care Excellence guidelines to determine the degree of clinical details given. Reported abnormalities, recommended management, and correspondence were recorded.Results:Ninety-one referrals were received during the 6-month audit period. More than half lacked a clinical indication for referral (53/91, 58.2%), with fewer than one third (26/91, 28.5%) meeting National Institute for Health and Care Excellence criteria for referral for cardiology. Eighty (80/91) referrals had clinical outcomes available for review (missing outpatient department information and age outside of service range accounted for eleven referrals with unavailable clinical outcomes). Of the eighty clinically reviewed referrals, seventy-two (72/80, 90%) were reported as normal with no cardiology follow up required. Eight referrals (8/80, 10%) were reviewed in the Cardiology Outpatient Department prior to commencement or modifying attention deficit hyperactivity disorder medication. Of these, only one (1/80 1%) had a clinically significant abnormality which was a potential contraindication to attention deficit hyperactivity disorder medication use, and this referral was appropriate as per National Institute for Health and Care Excellence guidelines.Conclusion:Routine screening prior to attention deficit hyperactivity disorder medication prescription in the absence of clinical indications (as per National Institute for Health and Care Excellence) contributed to delays in medication initiation among young people with attention deficit hyperactivity disorder. Unnecessary referrals have resource implications for cardiology clinical team. Improved adherence to National Institute for Health and Care Excellence guidelines would provide benefits for patients and clinicians.
Food poverty among children aged 6–59 months in Brazil: results from the Brazilian National Survey on Child Nutrition (ENANI-2019)
Authors: Carneiro Letícia Barroso Vertulli , Lacerda Elisa Maria de Aquino , Oliveira Natália , Schincaglia Raquel Machado , Alves-Santos Nadya Helena , Berti Talita Lelis , Crispim Sandra Patricia , Farias Dayana Rodrigues , Mello Juliana Vieira de Castro , Normando Paula , Castro Inês Rugani Ribeiro , Kac Gilberto 
Published: September 2024

Abstract

Objective:
To describe the prevalence of food poverty according to dimensions of socio-economic inequality and the food groups consumed by Brazilian children.

Design:
Dietary data from a structured qualitative questionnaire collected by the Brazilian National Survey on Child Nutrition (ENANI-2019) were used. The new UNICEF indicator classified children who consumed 3–4 and <3 out of the eight food groups as living in moderate and severe food poverty, respectively. The prevalence of consumption of each food group and ultra-processed foods (UPF) was estimated by level of food poverty according to age categories (6–23; 24–59 months). The most frequent combinations of food groups consumed by children living in severe food poverty were calculated. Prevalence of levels of food poverty were explored according to socio-economic variables.

Setting:
123 municipalities of the five Brazilian macro-regions.

Participants:
12 582 children aged 6–59 months.

Results:
The prevalence of moderate and severe food poverty was 32·5 % (95 % CI 30·1, 34·9) and 6·0 % (95 % CI 5·0, 6·9), respectively. Children whose mother/caregiver had lower education (<8 years) and income levels (per capita minimum wage <¼) had the highest severe food poverty prevalence of 8·3 % (95 % CI 6·2, 10·4) and 7·5 % (95 % CI 5·6, 9·4), respectively. The most consumed food groups among children living in food poverty in all age categories were ‘dairy products’, ‘grains, roots, tubers, and plantains’ and ‘ultra-processed foods’.

Conclusion:
Food poverty prevalence was high among Brazilian children. A significant occurrence of milk consumption associated with grains and a considerable prevalence of UPF consumption were found among those living in severe food poverty.
An Instrument Error Budget for Space‐Based Absolute Flux Measurements of the Sky Synchrotron Spectrum Below 20 MHz
Authors: Rolla J. , Romero‐Wolf A. , Lazio T. J. W. 
Published: September 2024

AbstractThis work describes the instrumental error budget for space‐based measurements of the absolute flux of the sky synchrotron spectrum at frequencies below the ionospheric cutoff (20 MHz). We focus on an architecture using electrically short dipoles onboard a small satellite. The error budget combines the contributions of the dipole dimensions, plasma noise, stray capacitance, and front‐end amplifier input impedance. We treat the errors using both a Monte Carlo error propagation model and an analytical method. This error budget can be applied to a variety of experiments and used to ultimately improve the sensing capabilities of space‐based electrically short dipole instruments. The impact of individual uncertainty components, particularly stray capacitance, is explored in more detail.
The Role of the Polar Vortex Jet for Secondary and Higher‐Order Gravity Waves in the Northern Mesosphere and Thermosphere During 11–14 January 2016
Authors: Vadas Sharon L. , Becker Erich , Bossert Katrina , Hozumi Yuta , Stober Gunter , Harvey V. Lynn , Baumgarten Gerd , Hoffmann Lars 
Published: September 2024

AbstractWe analyze the gravity waves (GWs) from the ground to the thermosphere during 11–14 January 2016 using the nudged HI Altitude Mechanistic general Circulation Model. We find that the entrance, core and exit regions of the polar vortex jet are important for generating primary GWs and amplifying GWs from below. These primary GWs dissipate in the upper stratosphere/lower mesosphere and deposit momentum there; the atmosphere responds by generating secondary GWs. This process is repeated, resulting in medium to large‐scale higher‐order, thermospheric GWs. We find that the amplitudes of the secondary/higher‐order GWs from sources below the polar vortex jet are exponentially magnified. The higher‐order, thermospheric GWs have concentric ring, arc‐like and planar structures, and spread out latitudinally to 10 − 90°N. Those GWs with the largest amplitudes propagate against the background wind. Some of the higher‐order GWs generated over Europe propagate over the Arctic region then southward over the US to ∼15–20°N daily at ∼14 − 24 UT (∼9 − 16 LT) due to the favorable background wind. These GWs have horizontal wavelengths λH ∼ 200 − 2,200 km, horizontal phase speeds cH ∼ 165 − 260 m/s, and periods τr ∼ 0.3 − 2.4 hr. Such GWs could be misidentified as being generated by auroral activity. The large‐scale, higher‐order GWs are generated in the lower thermosphere and propagate southwestward daily across the northern mid‐thermosphere at ∼8–16 LT with λH ∼ 3,000 km and cH ∼ 650 m/s. We compare the simulated GWs with those observed by AIRS, VIIRS/DNB, lidar and meteor radars and find reasonable to good agreement. Thus the polar vortex jet is important for facilitating the global generation of medium to large‐scale, higher‐order thermospheric GWs via multi‐step vertical coupling.
PET imaging in rat brain shows opposite effects of acute and chronic alcohol exposure on phosphodiesterase-4B, an indirect biomarker of cAMP activity
Authors: Tang Shiyu , Kim Sung Won , Olsen-Dufour Amanda , Pearson Torben , Freaney Michael , Singley Erick , Jenkins Madeline , Burkard Nathaniel J. , Wozniak Aaron , Parcon Paul , Wu Shawn , Morse Cheryl L. , Jana Susovan , Liow Jeih-San , Zoghbi Sami S. , Vendruscolo Janaina C. M. , Vendruscolo Leandro F. , Pike Victor W. , Koob George F. , Volkow Nora D. , Innis Robert B. 
Published: September 2024

Abstract
The cyclic adenosine monophosphate (cAMP) cascade is thought to play an important role in regulating alcohol-dependent behaviors, with potentially opposite effects following acute versus chronic administration. Phosphodiesterase 4 (PDE4) is the primary brain enzyme that metabolizes cAMP, thereby terminating its signal. Radioligand binding to PDE4 serves as an indirect biomarker of cAMP activity, as cAMP-protein kinase A (PKA)-mediated phosphorylation of PDE4 increases its affinity for radioligand binding ~10-fold. Of the four PDE4 subtypes, PDE4B polymorphisms are known to be strongly associated with alcohol and substance use disorders. This study imaged rats with the PDE4B-preferring positron emission tomography (PET) radioligand [18F]PF-06445974 following acute and chronic ethanol administration, aiming to explore the potential of PDE4B PET imaging for future human studies. Compared to the control group treated with saline, acute alcohol administration (i.p. ethanol 0.5 g/kg) significantly increased whole brain uptake of [18F]PF-06445974 as early as 30 minutes post-exposure. This effect persisted at 2 hours, peaked at 4 hours, and diminished at 6 hours and 24 hours post-exposure. In contrast, in a rat model of alcohol dependence, [18F]PF-06445974 brain uptake was significantly reduced at 5 hours post-exposure and was normalized by 3 days. This reduction may reflect long-term adaptation to repeated alcohol-induced activation of cAMP signaling with chronic exposure. Taken together, the results suggest that PET imaging of PDE4B in individuals with alcohol use disorder (AUD) should be considered in conjunction with ongoing trials of PDE4 inhibitors to treat alcohol withdrawal and reduce alcohol consumption.
P-tau217 and other blood biomarkers of dementia: variation with time of day
Authors: della Monica Ciro , Revell Victoria , Atzori Giuseppe , Laban Rhiannon , Skene Simon S. , Heslegrave Amanda , Hassanin Hana , Nilforooshan Ramin , Zetterberg Henrik , Dijk Derk-Jan 
Published: September 2024

AbstractPlasma biomarkers of dementia, including phosphorylated tau (p-tau217), offer promise as tools for diagnosis, stratification for clinical trials, monitoring disease progression, and assessing the success of interventions in those living with Alzheimer’s disease. However, currently, it is unknown whether these dementia biomarker levels vary with the time of day, which could have implications for their clinical value. In two protocols, we studied 38 participants (70.8 ± 7.6 years; mean ± SD) in a 27-h laboratory protocol with either two samples taken 12 h apart or 3-hourly blood sampling for 24 h in the presence of a sleep–wake cycle. The study population comprised people living with mild Alzheimer’s disease (PLWA, n = 8), partners/caregivers of PLWA (n = 6) and cognitively intact older adults (n = 24). Single-molecule array technology was used to measure phosphorylated tau (p-tau217) (ALZpath), amyloid-beta 40 (Aβ40), amyloid-beta 42 (Aβ42), glial fibrillary acidic protein, and neurofilament light (NfL) (Neuro 4-Plex E). Analysis with a linear mixed model (SAS, PROC MIXED) revealed a significant effect of time of day for p-tau217, Aβ40, Aβ42, and NfL, and a significant effect of participant group for p-tau217. For p-tau217, the lowest levels were observed in the morning upon waking and the highest values in the afternoon/early evening. The magnitude of the diurnal variation for p-tau217 was similar to the reported increase in p-tau217 over one year in amyloid-β-positive mild cognitively impaired people. Currently, the factors driving this diurnal variation are unknown and could be related to sleep, circadian mechanisms, activity, posture, or meals. Overall, this work implies that the time of day of sample collection may be relevant in the implementation and interpretation of plasma biomarkers in dementia research and care.
Polarization-entangled photons from a whispering gallery resonator
Authors: Huang Sheng-Hsuan , Dirmeier Thomas , Shafiee Golnoush , Laiho Kaisa , Strekalov Dmitry V. , Leuchs Gerd , Marquardt Christoph 
Published: September 2024

AbstractCrystalline whispering gallery mode resonators (WGMRs) have been shown to facilitate versatile sources of quantum states that can efficiently interact with atomic systems. These features make WGMRs an efficient platform for quantum information processing. Here, we experimentally show that it is possible to generate polarization entanglement from WGMRs by using an interferometric scheme. Our scheme gives us the flexibility to control the phase of the generated entangled state by changing the relative phase of the interferometer. The S value of Clauser–Horne–Shimony–Holt’s inequality in the system is 2.45 ± 0.07, which violates the inequality by more than six standard deviations.
A randomised crossover trial of nitrate and breakfast on prefrontal cognitive and haemodynamic response functions
Authors: Heiland Emerald G. , Lindh Frida , Regan Callum , Ekblom Örjan , Kjellenberg Karin , Larsen Filip J. , Fernström Maria , Nyberg Gisela , Ekblom Maria M. , Helgadóttir Björg 
Published: September 2024

AbstractIt remains unknown whether dietary nitrate and breakfast may enhance working memory (WM) performance by augmenting physiological mechanisms and subjective psychological well-being. We performed a 3-arm randomised within-subject crossover study, with pretest-posttest comparisons, to test whether nitrate consumption via breakfast with a beetroot juice shot or regular breakfast compared to no breakfast improved WM (measured with n-back tests) and cognitive task-related changes in prefrontal cortical haemodynamic response (oxygenated- and deoxygenated-haemoglobin derived from functional near-infrared spectroscopy). In addition, effects on peripheral vascular function and self-reported psychological factors were assessed. In 60 adolescents (13–15 years old; 66% girls), WM improved in all conditions, with no intervention effects. Intervention effects were seen for oxygenated-haemoglobin changes, such that it increased after the breakfast with a nitrate shot during the WM tests and decreased after the regular breakfast. Thus, different neurophysiological mechanisms may be at play to preserve WM in adolescents depending on their breakfast composition. The trial was registered in the ISRCTN registry (ISRCTN16596056) on 21/02/2022.
Label-free assessment of complement-dependent cytotoxicity of therapeutic antibodies via a whole-cell MALDI mass spectrometry bioassay
Authors: Schmidt Stefan , Geisel Alexander , Enzlein Thomas , Fröhlich Björn C. , Pritchett Louise , Verneret Melanie , Graf Christian , Hopf Carsten 
Published: September 2024

AbstractPotency assessment of monoclonal antibodies or corresponding biosimilars in cell-based assays is an essential prerequisite in biopharmaceutical research and development. However, cellular bioassays are still subject to limitations in sample throughput, speed, and often need costly reagents or labels as they are based on an indirect readout by luminescence or fluorescence. In contrast, whole-cell Matrix-Assisted Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry (MS) has emerged as a direct, fast and label-free technology for functional drug screening being able to unravel the molecular complexity of cellular response to pharmaceutical reagents. However, this approach has not yet been used for cellular testing of biologicals. In this study, we have conceived, developed and benchmarked a label-free MALDI-MS based cell bioassay workflow for the functional assessment of complement-dependent cytotoxicity (CDC) of Rituximab antibody. By computational evaluation of response profiles followed by subsequent m/z feature annotation via fragmentation analysis and trapped ion mobility MS, we identified adenosine triphosphate and glutathione as readily MS-assessable metabolite markers for CDC and demonstrate that robust concentration–response characteristics can be obtained by MALDI-TOF MS. Statistical assay performance indicators suggest that whole-cell MALDI-TOF MS could complement the toolbox for functional cellular testing of biopharmaceuticals.
Estimation of the crop evapotranspiration for Udham Singh Nagar district using modified Priestley-Taylor model and Landsat imagery
Authors: Satpathi Anurag , Danodia Abhishek , Abed Salwan Ali , Nain Ajeet Singh , Al-Ansari Nadhir , Ranjan Rajeev , Vishwakarma Dinesh Kumar , Gacem Amel , Mansour Lamjed , Yadav Krishna Kumar 
Published: September 2024

AbstractThe main challenges for utilizing daily evapotranspiration (ET) estimation in the study area revolve around the need for accurate and reliable data inputs, as well as the interpretation of ET dynamics within the context of local agricultural practices and environmental conditions. Factors such as cloud cover, atmospheric aerosols, and variations in land cover pose challenges to the precise estimation of ET from remote sensing data. This research aimed to utilize Landsat 8 and 9 datasets from the 2022–23 period in the Udham Singh Nagar district to apply the modified Priestley-Taylor (MPT) model for estimating ET. An average ET was estimated 1.33, 1.57, 1.70, 2.99, and 3.20 mm day−1 with 0.29, 0.33, 0.41, 0.69, and 1.03 standard deviation for December, January, February, March, and April month, respectively. In the validation phase, a strong correlation was found between the evaporative fraction derived from MPT and that observed by lysimeter, with R2 = 0.71, mean biased error = 0.04 mm day−1, root mean squared error = 0.62 mm day-1 and agreement index of 0.914. These results collectively support the effectiveness of the MPT model in accurately estimating ET across Udham Singh Nagar district. In essence, this research not only confirms the MPT model’s capability in ET estimation but also offers detailed insights into the spatial and temporal fluctuations of energy fluxes and daily ET rates.
Gate modulation of barrier height of unipolar vertically stacked monolayer ReS2/MoS2 heterojunction
Authors: Polumati Gowtham , Kolli Chandra Sekhar Reddy , Kumar Aayush , Salazar Mario Flores , De Luna Bugallo Andres , Sahatiya Parikshit 
Published: September 2024

AbstractThis study investigates vertically stacked CVD grown ReS2/MoS2 unipolar heterostructure device as Field Effect Transistor (FET) device wherein ReS2 on top acts as drain and MoS2 at bottom acts as source. The electrical measurements of ReS2/MoS2 FET device were carried out and variation in Ids (drain current) Vs Vds (drain voltage) for different Vgs (gate voltage) revealing the n-type device characteristics. Furthermore, the threshold voltage was calculated at the gate bias voltage corresponding to maximum transconductance (gm) value which is ~ 12 V. The mobility of the proposed ReS2/MoS2 heterojunction FET device was calculated as 60.97 cm2 V−1 s−1. The band structure of the fabricated vDW heterostructure was extracted utilizing ultraviolet photoelectron spectroscopy and the UV–visible spectroscopy revealing the formation of 2D electron gas (2DEG) at the ReS2/MoS2 interface which explains the high carrier mobility of the fabricated FET. The field effect behavior is studied by the modulation of the barrier height across heterojunction and detailed explanation is presented in terms of the charge transport across the heterojunction.