bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current clinical framework on nitric oxide role in periodontal disease and blood pressure
Authors: Lima Leonel , Gaspar Sara , Rocha Bárbara S. , Alves Ricardo , Almeida M. Gabriela 
Published: September 2024

Abstract
Objectives
In this review, we explored potential associations between NO and its derivatives, nitrite and nitrate, with periodontal and cardiovascular diseases, with special emphasis on the former. By providing a state-of-the-art and integrative understanding of this topic, we aimed to shed light on the potential role of these three nitrogen oxides in the periodontitis-hypertension nexus, identify knowledge gaps, and point out critical aspects of the experimental methodologies.

Materials and methods
A comprehensive literature review was conducted on human salivary and plasma concentrations of nitrate and nitrite, and their impact on periodontal and cardiovascular health.

Results
A nitrate-rich diet increases nitrate and nitrite levels in saliva and plasma, promoting oral health by favorably altering the oral microbiome. Chlorhexidine (CHX) mouthrinses disrupt the nitrate-nitrite-NO pathway, reducing NO bioavailability, and potentially affecting blood pressure. This is because CHX eliminates nitrate-reducing bacteria, which are essential for NO production. Although endogenous NO production may be insufficient, the nitrate-nitrite-NO pathway plays a critical role in maintaining appropriate endothelial function, which is balanced by the microbiome and dietary nitrate intake. Dietary nitrate supplementation may lead to beneficial changes in the oral microbiome, thereby increasing the NO bioavailability. However, NO bioavailability can be compromised by reactive oxygen species (ROS) and the uncoupling of endothelial nitric oxide synthase (eNOS), leading to further ROS generation and creating a detrimental cycle. Studies on NO and periodontal disease have shown increased nitrite concentrations in patients with periodontal disease, although these studies have some methodological limitations. In terms of blood pressure, literature suggests that CHX mouthrinses may reduce the capacity of nitrate-reducing bacteria, potentially leading to an increase in blood pressure.

Conclusions
Several studies have suggested an association between NO levels and the development of cardiovascular and periodontal diseases. However, the exact mechanisms linking these diseases remains to be fully elucidated.

Clinical relevance
Nitric oxide (NO) is a signaling molecule that plays a crucial role in several physiological processes such as vascular homeostasis, inflammation, immune cell activity, and pathologies such as hypertension and periodontitis.
Study on the mechanisms of retardation of cement hydration by zinc and acceleration of hardening by sodium aluminate from crystallographic phase analysis
Authors: Yamada Kazuo , Ichikawa Tsuneki , Arai Hiroyuki , Yasukochi Takahito , Endo Kazuto 
Published: September 2024

AbstractZinc was focused on as an element causing hardening retardation due to delayed hydration of Ordinary Portland Cement (OPC), and its hardening inhibitory effect and the mechanism of hardening enhancement by sodium aluminate were analyzed by X-ray diffraction and scanning electron microscopy/energy dispersive X-ray spectroscopy. The addition of zinc hydroxide retarded hardening at more than 0.3 mass%, as previously reported, and zinc produced calcium zincate hydrates (qatranaite) and inhibited the hydration of tricalcium silicate (C3S), the main component of hydration of OPC. After the zinc had been fully consumed in qatranaite formation, C3S started normal hydration. The addition of sodium aluminate caused earlier re-hydration of C3S, which was inhibited by hydration, as the hydrates produced appeared to consume zincate anions. The rapid setting effect of sodium aluminate addition was also delayed by zinc hydroxide, but it was estimated that the addition of the same amount of zinc would ensure initial strength through early formation of hydrocalumite. In the longer term, strength was considered to be more enhanced by the onset of C3S hydration.
The maximum geometric mean criterion: revisiting the Markowitz–Samuelson debate: survey and analysis
Authors: Levy Haim 
Published: September 2024

AbstractBy the Almost First-degree Stochastic Dominance (AFSD) rule, corresponding only to economically relevant preferences, for an infinite horizon the $$theoretical$$

theoretical

claim of both Markowitz and Samuelson is not intact. However, for the practically more relevant case of the long but finite horizon, with stocks-bonds portfolios, Markowitz $$empirically$$

empirically

is right as we find that the MGM portfolio coincides with the optimal myopic portfolio for all risk aversion parameters $$\alpha < 1.7$$

α
<
1.7

. For $$\alpha \ge 1.7$$

α
≥
1.7

the MGM portfolio dominates by AFSD rule all optimal myopic portfolios, as long as the investment horizon is 12–15 years or longer.
Temporal graphs anomaly emergence detection: benchmarking for social media interactions
Authors: Lazebnik Teddy , Iny Or 
Published: September 2024

AbstractTemporal graphs have become an essential tool for analyzing complex dynamic systems with multiple agents. Detecting anomalies in temporal graphs is crucial for various applications, including identifying emerging trends, monitoring network security, understanding social dynamics, tracking disease outbreaks, and understanding financial dynamics. In this paper, we present a comprehensive benchmarking study that compares 12 data-driven methods for anomaly detection in temporal graphs. We conduct experiments on two temporal graphs extracted from Twitter and Facebook, aiming to identify anomalies in group interactions. Surprisingly, our study reveals an unclear pattern regarding the best method for such tasks, highlighting the complexity and challenges involved in anomaly emergence detection in large and dynamic systems. The results underscore the need for further research and innovative approaches to effectively detect emerging anomalies in dynamic systems represented as temporal graphs.
Parental Overprotection and Locus of Control as the Mechanisms Explaining the Relationship Between Parent and Child Anxiety: A Multiple Mediation Model
Authors: Yaffe Yosi 
Published: September 2024

AbstractThe study probes the role played by parenting control practices and parental locus of control in the relationship between parent and child anxiety. The study particularly aims at probing these matters in light of the parental gender-specific role, striving to improve our understanding of the differential etiological contribution of mothers’ and fathers’ anxiety and parental practices to child’s anxiety. The study consisted of 316 parents (159 mothers and 157 fathers) who reported their own and their child’s anxiety using valid instruments. The general path model used in the study exhibited an adequate fit to the data, generally confirming our theory regarding the direct and indirect associations between parent–child anxiety. Using SEM multiple group analysis for parental gender, a strong-direct unique association was found between parent and child anxiety. For mothers, this association was partially mediated by maternal overprotection. Finally, maternal external locus of control was positively associated with child anxiety, after accounting for the effects of all other maternal variables. The study’s findings and limitations are profoundly discussed in light of parental gender differences.
Training to Increase Processing of Positive Content Paradoxically Decreases Positive Memory Bias in High Levels of Depression
Authors: Kardosh Nour , Mor Nilly 
Published: September 2024

Abstract
Purpose
Depressive symptoms are associated with reduced processing of and memory for positive content. These cognitive biases maintain depressive states, and are presumed to be interrelated. This study examined the effect of a single-session training to process (or inhibit) positive stimuli, on memory of new emotional content.

Methods
Participants (N = 138) were randomly assigned to conditions designed to increase or inhibit processing of positive content. Then, they made self-referential judgments concerning positive, negative and neutral words. Lastly, they free-recalled the words and completed a depression questionnaire.

Results
Training was effective in directing participants’ processing efforts. However, the effect of the training on self-referential judgment and memory for new positive content was only significant when contingent on depression levels. Positive endorsement and recall biases were negatively affected by the positive training among participants with higher depression scores.

Conclusions
These findings shed light on possible adverse effects of extensive exposure to positive content in depression.
Modeling Asset Price Process: An Approach for Imaging Price Chart with Generative Diffusion Models
Authors: Park Jinseong , Ko Hyungjin , Lee Jaewook 
Published: September 2024

AbstractArtificial Intelligence (AI) models have been recently studied to discover data patterns for prediction and forecasting tasks in finance. However, the use of deep generative models in finance remains relatively unexplored. In this paper, we investigate the potential of deep generative diffusion models to estimate unknown dynamics using multiple simulations based on stock chart images. We first demonstrate a novel pre-processing framework and synthetic image generation using opening, high, low, and closing stock chart images to train neural networks. Without assuming the specific process as the underlying asset price process, we can generate synthetic data without predetermined assumptions of the underlying movements of stock prices by trained generative diffusion models. The experimental results demonstrate that the proposed method successfully replicates well-known asset price processes. With various simulation paths, we can also accurately estimate option pricing on the S &P 500. We conclude that financial simulation with AI can be a novel approach to financial decision-making.
Comparative analysis of phytoplankton diversity using microscopy and metabarcoding: insights from an eLTER station in the Northern Adriatic Sea
Authors: Neri Francesca , Ubaldi Marika , Accoroni Stefano , Ricci Sara , Banchi Elisa , Romagnoli Tiziana , Totti Cecilia 
Published: September 2024

AbstractThe monitoring of phytoplankton is crucial to highlight changes in the marine ecosystems. In the present study, the phytoplankton community of an eLTER station in the Northern Adriatic Sea was analysed combining two approaches, i.e. microscopy and eDNA metabarcoding (targeting V4 and V9 regions of the 18S rRNA gene, and using PR2 and SILVA as reference databases), to highlight the strengths and weaknesses of these two methods. Metabarcoding revealed a so far unknown phytoplankton diversity (99 genera and 151 species), while microscopy detected 14 genera and 44 species not revealed by metabarcoding. Only a small percentage of genera and species were shared by the two methods (microscopy and metabarcoding), 18S regions (V4 and V9) and reference databases (PR2 and SILVA). Metabarcoding showed a community characterized by a higher number of phytoflagellate and dinoflagellate genera and species, in comparison with microscopy where diatom and dinoflagellate taxa were the most represented. Moreover, metabarcoding failed to reveal almost all the coccolithophores. The results confirmed metabarcoding as a powerful tool, but it should still be combined with microscopy to have a more detailed information on the community and to counteract the drawbacks of metabarcoding, such as gaps in the reference databases.
A Conceptual Framework for Digital Twin in Healthcare: Evidence from a Systematic Meta-Review
Authors: Pellegrino Giulia , Gervasi Massimiliano , Angelelli Mario , Corallo Angelo 
Published: September 2024

AbstractDigital Twin (DT) technology monitors, simulates, optimizes, models, and predicts the behavior of physical entities. Healthcare is a significant domain where a DT can be functional for multiple purposes. However, these diverse uses of DTs need a clear understanding of both general and specific aspects that can affect their adoption and integration. This paper is a meta-review that leads to the development of a conceptual framework designed to support the high-level evaluation of DTs in healthcare. Using the PRISMA methodology, the meta-review synthesizes insights from 20 selected reviews out of 1,075 studies. Based on this comprehensive analysis, we extract the functional, technological, and operational aspects that characterize DTs in healthcare. Additionally, we examine the structural (e.g., hierarchical) relationships among these aspects to address the various complexity scales in digital health. The resulting framework can promote the effective design and implementation of DTs, offering a structured approach for their assessment.
German Parents Attaining Intrapersonal Work-Family Balance While Implementing the 50/50-Split-Model with Their Partners
Authors: Schaber Ronja , Patella Tirza , Simm Josefine , Garthus-Niegel Susan 
Published: September 2024

AbstractWork-family balance (WFB) is attained if parents combine work and family roles aligned with their values. For an egalitarian parent aiming to implement a 50/50-split-model, this means sharing paid work, childcare, and housework equally with their partner (involvement balance), performing well in all roles (effective balance), while having positive emotions (emotional balance). This is difficult since work and family are competing for time and attention. Therefore, this article presents resources which can help parents attain WFB within a 50/50-split-model. Quantitative data of n = 1036 couples participating in the Dresden Study on Parenting, Work, and Mental Health (DREAM) were used to calculate the implementation rate of the 50/50-split-model at 14 months postpartum. Quantitative DREAM data were screened to purposively select n = 25 participants implementing a 50/50-split-model for the qualitative study DREAMTALK. Problem-centered interviews were conducted and analyzed via qualitative content analysis. Quantitative results showed a 50/50-split-model implementation rate of 3.8–17.5% among German parents. Qualitative results revealed 14 individual- and eight macro-level resources to facilitate WFB within a 50/50-split-model. Individual-level examples are acknowledging benefits of childcare assistance, segmentation from paid work and controversially, in other situations, integration of paid work and family. Macro-level examples are availability of childcare assistance, of solo paternal leave, paid work < 39 h/week, employee flexibility options, and family-friendly workplace cultures. To conclude, the full potential of individual-level resources applied by parents is attained when supported by macro-level resources provided by politics and employers. Parents, politics, and employers can facilitate WFB within the 50/50-split-model to foster gender equality.
On the synthesis and formability of high-entropy oxides
Authors: Kandage Manjula M. , Marszewski Michal 
Published: September 2024

AbstractThis paper reports on a straightforward and general solution-based synthesis method for high-entropy oxides (HEOs) of different types and compositions. The flexibility and simplicity of this method are hoped to drive development of new HEOs and study of their properties and applications. Thirteen HEOs with rock salt, fluorite, spinel, and perovskite structures were synthesized using a Pechini-type synthesis at temperatures significantly lower than those necessary in solid-state synthesis (400–900 °C). Metal nitrates, nitrites, chlorides, and even water-sensitive alkoxides were used as the metal precursors with the present method. The HEOs were characterized using powder X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. Relaxation of cation size and charge rules and formability of HEOs are also discussed. The present results indicate that the classical criteria for material stability do not readily translate to high-entropy systems. For example, the well-known criteria for Goldschmidt and octahedral tolerance factors established for ordinary perovskites do not seem to describe formability of perovskite HEOs well. The discussed relaxation of cation size and charge rules will contribute to the understanding of HEO systems and development of new HEO phases.
High-temperature oxidation behaviour of additively manufactured and wrought HAYNES 282
Authors: Kopec Mateusz , Mierzejewska Izabela , Gorniewicz Dominika , Sitek Ryszard , Jóźwiak Stanisław 
Published: September 2024

AbstractDirect Metal Laser Sintered Haynes 282 specimens as well as wrought ones were subjected to high-temperature exposure at 1000 °C for 100h in air to compare their oxidation behaviour. The specimens were removed from the furnace after 1h, 5h, 25h, 50h and 100h to reveal and study oxidation mechanisms through morphological and cross-sectional examination by using scanning electron microscopy with energy dispersive spectroscopy attachment and X-ray diffraction. Microstructural studies revealed that the oxidation kinetics, determined by changes in thickness scale and depth of aluminium diffusion zone, were mainly driven by the formation of Cr2O3 for the wrought material, and TiO2 for DMLS one. The wrought material was characterized by the oxidation rate equal to 0.96 and followed the logarithmic law. On the other hand, DMLS-manufactured Haynes 282 exhibited oxidation rate of 0.90 and follows the linear law for the thickness scale considerations. However, when the depth of aluminium diffusion was investigated, it had an oxidation rate of 0.87 and followed cubic law.
Relationships between the qNOX, qCON, burst suppression ratio, and muscle activity index of the CONOX monitor during total intravenous anesthesia: a pilot study
Authors: Linassi Federico , Vide Sergio , Ferreira Ana , Schneider Gerhard , Gambús Pedro , Kreuzer Matthias 
Published: September 2024

AbstractBackground: Processed electroencephalographic (EEG) indices can help to navigate general anesthesia. The CONOX (Fresenius Kabi) calculates two indices, the qCON (hypnotic level) and the qNOX (nociception). The CONOX also calculates indices for electromyographic (EMG) activity and EEG burst suppression (BSR). Because all EEG parameters seem to influence each other, our goal was a detailed description of parameter relationships. Methods: We used qCON, qNOX, EMG, and BSR information from 14 patients receiving propofol anesthesia. We described index relationships with linear models, heat maps, and box plot representations. We also evaluated associations between qCON/qNOX and propofol/remifentanil effect site concentrations (ceP/ceR). Results: qNOX and qCON (qCON = 0.79*qNOX + 5.8; p < 0.001; R2 = 0.84) had a strong linear association. We further confirmed the strong relationship between qCON/qNOX and BSR for qCON/qNOX < 25: qCON=-0.19*BSR + 25.6 (p < 0.001; R2 = 0.72); qNOX=-0.20*BSR + 26.2 (p < 0.001; R2 = 0.72). The relationship between qCON and EMG was strong at higher indices: qCON = 0.55*EMG + 33.0 (p < 0.001; R2 = 0.68). There was no qCON > 80 without EMG > 0. The relationship between ceP and qCON was qCON=-3.8*ceP + 70.6 (p < 0.001; R2 = 0.11). The heat maps also suggest that the qCON and qNOX can at least partially separate the hypnotic and analgetic components of anesthesia. Conclusion: We could describe relationships between qCON, qNOX, EMG, BSR, ceP, and ceR, which may help the anaesthesiologist better interpret the information provided. One major finding is the dependence of qCON > 80 on EMG activity. This may limit the possibility of detecting wakefulness in the absence of EMG. Further, qNOX seems generally higher than qCON, but high opioid doses may lead to higher qCON than qNOX indices.
Post-separation Child Contact and Domestic Violence and Abuse: The Experiences of Children with a Disability
Authors: Gregory Soma , Elliffe Ruth , Holt Stephanie , Donnellan Rachel , Cahill Lynne 
Published: September 2024

Abstract
Purpose
This article addresses a gap in empirical knowledge on post-separation contact in the context of domestic violence and abuse (DVA) for children with disabilities. The intersection of disability and DVA is explored through the mother’s perspective and brings to the fore the unique experiences of children with disabilities in the post-separation contact space.

Methods
Known to be a difficult to reach population, the experience of disabled children were captured through in-depth qualitative interviews with a sample of eight victim/survivor mothers. Mothers were recruited through gatekeepers from a voluntary children’s organization and specialist DVA services. Autism spectrum disorder (ASD) was the most common disability occurring in the sample.

Results
Three major themes relating to the disabled child’s experience were identified: (i) Courts’ (lack of) consideration of children’s disability in post-separation child contact decision-making; (ii) Disruption to routine; and (iii) Quality of contact. Participating mothers reported that these experiences caused serious emotional distress for the children; distress that was heightened and compounded by their disability status.

Conclusion
Applying an intersectional lens to the experiences of children with a disability who live with DVA, this study simultaneously illuminates children’s vulnerability and marginalization in this context, whilst also identifying gaps in policy and practice responses to identify and address the individual needs of these children. Lastly, given the nascent evidence base on this topic, research which directly elicits the voice of the child is urgently needed.
The EUropeanisation of Research Infrastructure Policy
Authors: Cramer Katharina C. , Rüffin Nicolas V. 
Published: September 2024

AbstractPolitical interest in Research Infrastructures on a European scale has been a new phenomenon, marked in the early 2000s with the launch of the Lisbon Strategy and the European Research Area. European Research Infrastructure policy then developed through, first, the strategic incorporation of incumbents through new modes of coordination; second, the European Commission’s emphasis of joint responsibility at the supranational level, claiming its own accountability and mobilizing the subsidiarity principle to its advantage; third, the incentivization of conformity to the European Commission’s policy agenda through generous financial schemes and fourth, the implementation of tailor-made legislation. While this topic speaks to current debates in EU studies, it also amends analyses of Big Science as an empirical puzzle within European politics and integration and launches a scholarly effort to come to terms with the new phenomenon of Research Infrastructures.