bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosing Borderline Personality Disorder During Adolescence: A Review of the Published Literature
Authors: Fossati Andrea 
Published: July 2016

Abstract
Borderline personality disorder (BPD) is a debilitating disorder that occurs in approximately 1% to 3% of the general population. BPD is not only relatively prevalent; it is also associated with significant public health and security concerns. The clinical and social burden of adult BPD diagnosis has resulted in the desire for early diagnosis and the implementation of early intervention programs. A qualitative review of the scientific literature suggested that adolescence is a critical point for the early identification and therapeutic treatment of BPD. Although findings are far from conclusive, the inter-rater reliability and internal consistency of the Diagnostic and Statistical Manual of Mental Disorders symptom criteria for BPD during adolescence seem adequate. Recent studies based on a rigorous methodology of BPD assessment and large community samples reported prevalence rates for BPD diagnosis during adolescence that were less suspect than previous findings. A number of research studies addressed the construct validity of BPD in adolescents (i.e., whether a BPD diagnosis during adolescence actually measures what is intending to measure) and reported consistent relationships between BPD and associated areas of dysfunction and distress as evidence of the validity of the BPD diagnosis. Research evidence indicates that there is no single symptom that is predictive of later BPD diagnosis during adolescence; rather, a pattern of two to three selected BPD symptoms that are evident during adolescence seemed to be highly predictive of later BPD diagnosis, particularly when measures that were specifically designed to assess for BPD during adolescence were used as part of the assessment process.
The Accuracy of the VISA-P Questionnaire, Single-Leg Decline Squat, and Tendon Pain History to Identify Patellar Tendon Abnormalities in Adult Athletes
Authors: Mendonça Luciana de Michelis , Ocarino Juliana Melo , Bittencourt Natália Franco Netto , Fernandes Ludmila Maria Oliveira , Verhagen Evert , Fonseca Sérgio Teixeira 
Published: July 2016

Study Design Cross-sectional clinical assessment. Background Patellar tendinopathy is not always accompanied by patellar tendon abnormalities (PTAs). Thus, clinical screening tools to help identify patients with patellar tendon pain who have PTAs could enhance clinical decision making and patient prognosis. Objectives To test the diagnostic accuracy of the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire, a single-leg decline squat (SLDS), tendon pain history, age, and years of sports participation to identify athletes with symptomatic patellar tendons who have PTAs confirmed on imaging. Methods Data provided by ultrasound examination, the VISA-P questionnaire, the SLDS, tendon pain history, age, and years of sport participation were collected in 43 athletes. A classification and regression tree (CART) model was developed to verify variables associated with PTA occurrence. Likelihood ratios (LRs) were computed for positive and negative tests. Results The SLDS, VISA-P questionnaire, and tendon pain history were associated with PTA occurrence. Athletes with negative results on all 3 tests (CART model) had a lower likelihood of having PTAs (negative LR = 0.3; 95% confidence interval [CI]: 0.2, 0.5). The isolated use of the SLDS or tendon pain history (positive LR = 4.2; 95% CI: 2.3, 7.14 and 4.5; 95% CI: 1.8, 11.1, respectively) had similar influence on probability of PTA presence compared to the CART model (positive LR = 4.1; 95% CI: 2.5, 6.3). Conclusion Although the objective was to investigate a clinical test to identify PTAs, the combined use of the tests had greater accuracy to identify individuals without PTAs. Level of Evidence Diagnosis, level 3b. J Orthop Sports Phys Ther 2016;46(8):673–680. Epub 3 Jul 2016. doi:10.2519/jospt.2016.6192
Postural Stability During Single-Leg Stance: A Preliminary Evaluation of Noncontact Lower Extremity Injury Risk
Authors: Dingenen Bart , Malfait Bart , Nijs Stefaan , Peers Koen H.E. , Vereecken Styn , Verschueren Sabine M.P. , Janssens Luc , Staes Filip F. 
Published: July 2016

Study Design Controlled laboratory study with a prospective cohort design. Background Postural stability deficits during single-leg stance have been reported in persons with anterior cruciate ligament (ACL) injury, ACL reconstruction, and chronic ankle instability. It remains unclear whether impaired postural stability is a consequence or cause of these injuries. Objectives To prospectively investigate whether postural stability deficits during single-leg stance predict noncontact lower extremity injuries. Methods Fifty injury-free female athletes performed a transition task from double-leg stance to single-leg stance with eyes closed. Center-of-pressure displacement, the main outcome variable, was measured during the first 3 seconds after the time to a new stability point was reached during single-leg stance. Noncontact lower extremity injuries were recorded at a 1-year follow-up. Results Six participants sustained a noncontact ACL injury or ankle sprain. Center-of-pressure displacement during the first 3 seconds after the time to a new stability point was significantly increased in the injured (P = .030) and noninjured legs (P = .009) of the injured group compared to the respective matched legs of the noninjured group. The area under the receiver operating characteristic curve (AUC) analysis revealed significant discriminative accuracy between groups for the center-of-pressure displacement during the first 3 seconds after the time to a new stability point of the injured (AUC = 0.814, P = .015) and noninjured legs (AUC = 0.897, P = .004) of the injured group compared to the matched legs of the noninjured group. Conclusion This preliminary study suggests that postural stability measurements during the single-leg stance phase of the double- to single-leg stance transition task may be a useful predictor of increased risk of noncontact lower extremity injury. Further research is indicated. Level of Evidence Prognosis, level 4. J Orthop Sports PhysTher 2016;46(8):650–657. Epub 3 Jul 2016. doi:10.2519/jospt.2016.6278
Hip Strength Deficits in People With Symptomatic Knee Osteoarthritis: A Systematic Review With Meta-analysis
Authors: Deasy Margaret , Leahy Edmund , Semciw Adam Ivan 
Published: July 2016

Study Design Systematic review with meta-analysis. Background A complete understanding of impairments associated with knee osteoarthritis would optimize exercise interventions for people with knee osteoarthritis. Our current understanding of hip strength deficits in this population is based on studies with conflicting findings and small samples. There is a need to systematically review and pool current evidence. Objectives To determine whether hip strength deficits exist in people with symptomatic knee osteoarthritis. Methods Electronic databases (MEDLINE, CINAHL, Embase, the Cochrane Library, and PsycINFO) were searched through February 2016. Studies comparing hip strength in people diagnosed with symptomatic knee osteoarthritis to healthy control participants were included in the review. A meta-analysis with random effects was applied to relevant data from included studies and a modified Grading of Recommendations Assessment, Development and Evaluation approach was used to evaluate the quality of evidence for each pooled analysis. Results Five studies were included in the review. Meta-analysis revealed moderate-quality evidence of weaker isometric and isokinetic hip abduction strength in people with knee osteoarthritis (moderate difference: 7% to 24% weaker) and very low-quality evidence of no difference in isometric hip adduction strength. There was very low- to moderate-quality evidence of weaker isokinetic hip strength in the remaining planes of motion (moderate to large differences: 14% to 55% weaker). Conclusion Significant hip strength deficits exist in people with knee osteoarthritis. Hip strength assessment should be considered in clinical practice and may assist with directing targeted management strategies. Level of Evidence Symptom prevalence, level 1a−. J Orthop Sports PhysTher 2016;46(8):629–639. Epub3 Jul 2016. doi:10.2519/jospt.2016.6618
Parental coping mechanisms in children with congenital heart disease at tertiary cardiac centre
Authors: Bajracharya Subina , Shrestha Ajit 
Published: July 2016

Background: Congenital Heart Diseases (CHD) are among the most pervasive and serious chronic illnesses. Parents of children with a chronic condition must cope with greater demands and adopt different behaviors in order to lessen the impact on the family structure.Aims and Objectives: This study aims to explore the coping mechanism used by parents of children with CHD.Materials and Methods: This descriptive study included 100 parents of children with CHD selected through non-probability purposive sampling technique. Data were collected by interview and analyzed using descriptive statistics.Result: This study revealed that parents of preschool children used more coping mechanism (mean score 30.53 out of total score 57), followed by parents of adolescence (mean score 30). Parents of first-born children with CHD used less coping mechanism (mean score 28.08). Parents of female children used more coping mechanism (mean score 29.52), fathers of children with CHD used more coping mechanism (mean score 29.78), and parents of operated children used more coping mechanism (mean score 29.11).Conclusion: Parental coping mechanism was found to be affected by age, sex, operative status and birth order of children and also by the sex of parent. These findings strongly indicate the need for proper counseling service to parents so that healthy coping is reinforced.Asian Journal of Medical Sciences Vol.7(4) 2016 75-79
Presence of choledocholithiasis in patients undergoing cholecystectomy for mild biliary pancreatitis
Authors: Pradhan S , Shah S , Maharjan S , Shah JN 
Published: July 2016

Introduction: Standard recommendations for patients recovering from an episode of biliary pancreatitis include cholecystectomy with intra operative cholangiogram or ERCP during the same hospital admission as it is believed that the instigating factor is the passage of stones through the common bile duct. As ERCP is not widely available and expensive, cholecystectomy with IOC is routinely performed to rule out choledocholithiasis. However detection of common bile duct stones is challenging. Whether these patients undergoing cholecystectomy require direct common bile duct evaluation is controversial. Objective of the study was to see the presence of common bile duct stones in patients with resolving acute mild biliary pancreatitis. Methods: Patients admitted in the surgical ward in Patan Hospital and Bir Hospital with the diagnosis of mild acute biliary pancreatitis who underwent cholecystectomy with intra-operative cholangiography from August 2010 to July 2012 were studied. The outcome of cholangiogram was analyzed together with findings of common bile duct exploration. Results: A total of 52 patients with acute mild biliary pancreatitis were operated during this period. The common bile duct stone was found in 1.9%. Out of four patients with abnormal cholangiogram, only one patient (25%) had stone on exploration, rest of the three cases (75%) had negative exploration.Conclusion: The presence of common bile duct stone in case of mild acute biliary pancreatitis undergoing cholecystectomy is very low (1.96%), and thus policy of selective IOC should be applied for cases with mild biliary pancreatitis.Journal of Society of Surgeons of Nepal Vol.17(1) 2014: 11-15
Unremarkable experiences - Designing the user experience of elevators
Authors: Rousi Rebekah 
Published: July 2016

Elevators enable people and goods to be transported to great heights at substantial speeds.The feats required technologically for suspension, movement, controls and safety are no less than remarkable. This is increasingly so when considering the competing new heights of skyscrapers. Although technological accomplishments are becoming ever more extraordinary, for the sake of those using the technologies, there is also the need to counter this remarkableness and consider the unremarkable as an experiential design goal. Discourse in user experience (UX) has mainly focused on designing for positive, affective and memorable experiences. However, in the case of utilitarian technologies such as elevators often good or positive experiences go unnoticed. The current study’s findings show just this. This article describes a study of UX with elevators using field observations and short interviews. Positive experiences were reflected in quantitative opinion scales related to the elevators under study. Negative experiences regarding previous elevator experiences were qualitatively recollected without prompting. The age and the detail of the recollected experiences suggest the significance negative (remarkable) events have on memory, influencing current and future impressions of elevator design. This calls for UX attention to be placed on designing for the unremarkable.
Design strategy: Towards a post-rational, practice-based perspective
Authors: Navarro Aguiar Ulises 
Published: July 2016

This paper critically reflects on the concept of design strategy as deployed in design management literature.
It starts by describing current discourses in the wider field of strategy research and then discusses how, by conforming to orthodox theories in strategic management, design management literature has tended to overlook alternative streams of strategy research.
In many instances, studies in design strategy adopt taken-for-granted assumptions from rational planning approaches, and analyses of firm performance tend to take precedence over actors and their actions. Thus, it highlights the need for new lines of inquiry grounded in practice, letting go of the economic rationality and theoretical abstractions that have permeated mainstream strategy research. Hence, for future studies, it suggests a post-rational, practice-based perspective to advance our understanding of strategy as it relates to design management.
Using an action research approach to embed service design in a higher education institution
Authors: Madden Heather , Walters Andrew T 
Published: July 2016

Design Thinking can address the political and cultural divides in higher education and improve the focus on student experience. The challenge is reshaping a traditional organisation into a more modern one and at the same time creating an environment that is favourable towards change brought about by design-led thinking.
In one higher education institute, almost two years into the journey and despite some challenges along the way, Service Design methods are demonstrating their capacity to change the processes and procedures that support the delivery of student services in higher education.
An action research approach is currently being used to assess how the tools of Design Thinking are applied to real organisational problems and the consequences of design-led action. This research introduces a new set of tools and techniques to an organisation and analyses the effects of this fresh approach on the organisation via a number of action research cycles. There are many stages on the road to introduce Design Thinking as a bottom-up approach to changing an organisation into a more innovative, progressive, efficient and user-centred one.
Checklist of British and Irish Hymenoptera - Ichneumonidae
Authors: Broad Gavin 
Published: July 2016

The checklist of British and Irish Ichneumonidae is revised, based in large part on the collections of the Natural History Museum, London and the National Museums of Scotland, Edinburgh. Distribution records are provided at the country level.
Of the 2,447 species regarded as valid and certainly identified, 214 are here recorded for the first time from the British Isles. Neorhacodinae is considered to be a separate subfamily rather than a synonym of Tersilochinae. Echthrini is treated as a junior synonym of the tribe Cryptini, not Hemigastrini. Echthrus Gravenhorst and Helcostizus Förster are classified in Cryptini rather than, respectively, Hemigastrini and Phygadeuontini.
Efficacy, Safety and Cost of Regorafenib in Patients with Metastatic Colorectal Cancer in French Clinical Practice
Authors: Calcagno Fabien , Lenoble Sabrina , Lakkis Zaher , Nguyen Thierry , Limat Samuel , Borg Christophe , Jary Marine , Kim Stefano , Nerich Virginie 
Published: July 2016

Background Regorafenib is an orally administered multikinase inhibitor that has been approved for patients with chemotherapy-refractory metastatic colorectal cancer (mCRC). Even though regorafenib significantly improved survival in two international phase 3 trials (CORRECT and CONCUR), a high rate of treatment-related toxic effects and dose modifications were observed with a modest benefit. The aim of this study was to provide information concerning the efficacy, safety, and cost of regorafenib in patients with mCRC in clinical practice. Material and Methods We retrospectively reviewed patients treated with regorafenib monotherapy for unresectable mCRC in five Franche-Comté cancer hospitals (France). The primary end point was overall survival. Secondary end points were safety and descriptive cost analyses of patients treated with regorafenib in clinical practice. Another aim of this study was to assess the impact of regorafenib prescription on the risk of hospitalization in real-life practice. Results From January 2014 to August 2014, 29 consecutive patients were enrolled. Patients were heavily pretreated and were refractory to standard chemotherapies. The primary tumor sites were the colon and the rectum for 55% and 45% of patients, respectively. Fifteen patients (51%) harbored an RAS mutation. Eastern Cooperative Oncology Group - Performance Status (PS) was 0–1 for 86% of patients and 2 for 14% of patients. Nineteen patients (66%) initially received reduced doses of 120 or 80 mg/day. The median duration of treatment was 2.5 months (range, 0.13–11.4 months). Treatment-related adverse events occurred in 86% of patients. The most frequent adverse events of any grade were fatigue (35%), diarrhea (20%), and hand-foot skin reaction (20%). Grade 3 or 4 treatment-related adverse events occurred in 10 patients (35%). Three patients (10%) were admitted to hospital due to drug-related severe adverse events. The mean cost of patient management with regorafenib for the duration of treatment was 9908 ± 8191€, and median cost was 7917€ (Interquartile range (IQR) 4469-13,042). The median overall survival was six months (95% confidence interval, five to eight months). Conclusions The safety and efficacy of regorafenib in heavily pretreated mCRC patients was comparable, in our study, to prospective and retrospective trials. Toxic effects were mostly manageable in an outpatient setting. Regorafenib itself represented the most important (93%) part of supported costs. Even though most side effects were manageable in an outpatient setting, severe adverse events occurred from hospitalization in 10% of patients. These data should be confirmed in a larger real-life-based cohort. Identification of predictive biomarkers is needed for mCRC patient selection for regorafenib treatment.
IMPACTO DA CIRURGIA ORTOGNÁTICA SOBRE A QUALIDADE DE VIDA DE PACIENTES ATENDIDOS NO SERVIÇO DA UNIVERSIDADE FEDERAL DO PARANÁ
Authors: CORSO Paola , SCARIOT Rafaela , OLIVEIRA Fábio Augusto Coelho , NASCIMENTO Luiza , REBELLATO Nelson 
Published: July 2016

A qualidade de vida vem sendo discutida e estudada cada vez mais nos últimos anos quando falamos em saúde, abrindo um leque para o estudo dos impactos que ela pode vir a trazer. A preocupação com a técnica nos procedimentos odontológicos começa a ser percebida de um novo ponto de vista, com maior enfoque no ser humano como um todo. Tendo em mente uma nova concepção de saúde, o “The Oral Health Impact Profile” (OHIP) é usado como intrumento para avaliar o impacto de problemas bucais no indivíduo, abrangendo as dimensões física, psicológica e social da vida diária. O OHIP14, versão resumida do OHIP, foi publicado por Slade em 1997. Este estudo, realizado na Universidade Federal do Paraná, avaliou o impacto na qualidade de vida dos pacientes submetidos a cirurgia ortognática a partir do uso desse questionário. O estudo mostrou um impacto negativo na qualidade de vida maior nos indivíduos que apresentam deformidades dentofaciais do que naqueles que não apresentam.
REMOÇÃO CIRÚRGICA DE ODONTOMA EM ÂNGULO MANDIBULAR: CONSIDERAÇÕES E ABORDAGEM CIRÚRGICA
Authors: PRIMO Bruno Tochetto , REBELLATO Nelson Luis Barbosa , STRINGHINI Diego José , KLUPPEL Leandro Eduardo , MULLER Paulo Roberto 
Published: July 2016

Os odontomas são classificados como tumores odontogênicos, com crescimento lento e comportamento não-agressivo, geralmente descobertos na segunda década de vida, sem predileção significativa por gênero. Embora predominantemente associados com os dentes permanentes, também ocorrem em associação com os dentes decíduos e são muitas vezes envolvidos com os dentes impactados Dois pacientes com queixa de aumento de volume em região de ângulo mandibular, com sinais, sintomas e exames de imagem compatíveis com odontoma complexo, associado a dentes impactados na base da mandíbula foram tratados pela técnica da osteotomia sagital do ramo mandibular (OSRM). Esta técnica foi escolhida para minimizar a remoção de tecido ósseo sadio, o que poderia fragilizar a estrutura óssea mandibular. Com o uso da OSRM foi possível realizar a exérese total dos tumores e extração dos dentes sem comprometimento sensorial ou motor permanente. Foi possível observar também o restabelecimento da oclusão pré-operatoria. As complicações potenciais devem ser analisadas em situações de lesões extensas e dentes profundamente retidos quando a cirurgia por acesso pela cortical vestibular ou lingual requer a remoção extensiva de osso alveolar, sendo que a OSRM pode ser uma técnica alternativa nessas situações.
Barreras para la utilización de la investigación. Estudio descriptivo en profesionales de Enfermería en un hospital del sudoeste de Madrid
Authors: Guadarrama Ortega David 
Published: July 2016

Objetivos. Identificar las situaciones, circunstancias o barreras que dificultan a la enfermería utilizar los resultados de las investigaciones en el Hospital Universitario Fundación Alcorcón (HUFA), así como sus facilitadores.<br /><br />Objetivos específicos. Evaluar si existen diferencias en la puntuación de la escala THE BARRIERS en función de las distintas variables estudiadas.<br /><br />Métodos. Estudio observacional, descriptivo y transversal durante mayo 2014. La población de estudio fueron todas las enfermeras que trabajan en el HUFA. El cuestionario que incluye la escala THE BARRIERS de S.Funk et al. se facilitó mediante una encuesta on-line distribuida a través del correo corporativo del hospital.<br /><br />Resultados. Respondieron 69 enfermeras (16%), fueron válidas 67 encuestas. Las barreras identificadas con mayor puntuación fueron: “La enfermera desconoce las investigaciones” media=3.33 (DE=0.89); y “Los médicos no colaboran en la implementación” media=3.26 (DE=0.86). Se encuentran diferencias estadísticamente significativas en la suma de la escala THE BARRIERS en función de la experiencia como enfermera, la formación post-grado, y haber realizado investigaciones previas. No se encuentran diferencias significativas en función del resto de variables.<br /><br />Conclusiones. Aunque la falta de tiempo se identifica como la principal barrera para la investigación en la mayoría de los estudios, aquí aparece por detrás de otras como el desconocimiento de las investigaciones, la falta de colaboración, o que la información no está recogida en un solo lugar. Sin embargo el tiempo aparece como una de las principales barreras en las respuestas de texto libre. <br /><br />