bluuebunny/crossref_metadata_2025_split huggingface dataset:
Near-surface geophysical surveys at the Duport gold deposit, Ontario, Canada: Relating airborne responses to small-scale geologic features
Authors: Ferguson Ian J. , Young Jeffrey B. , Cook Becky J. , Krakowka Ashley B. C. , Tycholiz Cassandra 
Published: July 2016

Near-surface geophysical measurements using magnetometer, magnetic susceptibility, terrain conductivity, and time-domain electromagnetic instruments were made at the shear-hosted Duport gold deposit on Cameron Island in Shoal Lake, western Ontario, Canada, to help relate airborne total magnetic intensity (TMI) and helicopter electromagnetic survey data to small-scale geologic features. The magnetic airborne response provides a weak indication of a narrow anomaly within the Duport deformation zone, and the airborne electromagnetic response provides an indication of enhanced conductivity in the northwest of Cameron Island. In contrast, surface magnetic responses are dominated by the narrow 10,000–15,000 nT magnetic anomaly of a talc-chlorite-dolomite schistose basalt unit, a feature barely visible in the airborne TMI data. This geologic unit hosts the veins containing gold mineralization, so the surface TMI data provide a valuable response for delineating the corresponding rocks. Modeling of the TMI data indicates that the unit has a susceptibility of up to 0.7 SI and a corresponding magnetite content of up to 20%. The TMI data also reveal along-strike variations in the magnetic anomaly providing information on the component of ultramafic rocks in the protolith of the unit. The surface geophysical data allow the enhanced conductivity in the northwest part of Cameron Island to be attributed to several narrow sulfidized zones containing up to 10% pyrrhotite. Additional conductive and positively magnetized zones are associated with concentrations of 5%–10% of magnetite. The near-surface geophysics at the Duport deposit provided a rapid and inexpensive method for defining the magnetic and electrical properties of the geologic units at the site and for defining the exact location, width, and internal structure of features observed in the airborne geophysical data. Availability of magnetic susceptibility measurements from a single drill core enhanced the accuracy of the interpretations and the ability to relate the near-surface geophysical responses to geologic features.
Seismic noise monitoring of the water table in a deep-seated, slow-moving landslide
Authors: Voisin Christophe , Garambois Stéphane , Massey Chris , Brossier Romain 
Published: July 2016

Daily correlations of ambient seismic noise on a large landslide at Utiku, New Zealand, reveal seismic velocity changes up to [Formula: see text] that follow a summer/winter cycle consistent with the pore-water pressures monitored at the basal slip surface in the landslide. The annual pattern of velocity changes is borne by a limited frequency band (6–8 Hz typically) that suggests a localized change in the medium. The Rayleigh waves that form the seismic signal within this frequency band have a maximum sensitivity at a depth of 2–3 m below the ground surface, consistent with the water table level. Fluid saturation changes in the landslide modeled using the Biot-Gassmann theory explain the limited frequency band and the amplitude of the seismic velocity change. This set of arguments suggests that seismic noise correlations are sensitive to water table oscillations through saturation changes and could be used as a nondestructive hydrologic monitoring tool.
Association Between Results of a Gene Expression Signature Assay and Recurrence-Free Interval in Patients With Stage II Colon Cancer in Cancer and Leukemia Group B 9581 (Alliance)
Authors: Niedzwiecki Donna , Frankel Wendy L. , Venook Alan P. , Ye Xing , Friedman Paula N. , Goldberg Richard M. , Mayer Robert J. , Colacchio Thomas Anthony , Mulligan Jude Marie , Davison Timothy S. , O’Brien Eamonn , Kerr Peter , Johnston Patrick G. , Kennedy Richard D. , Harkin D. Paul , Schilsky Richard L. , Bertagnolli Monica M. , Warren Robert S. , Innocenti Federico 
Published: July 2016

Purpose Conventional staging methods are inadequate to identify patients with stage II colon cancer (CC) who are at high risk of recurrence after surgery with curative intent. ColDx is a gene expression, microarray-based assay shown to be independently prognostic for recurrence-free interval (RFI) and overall survival in CC. The objective of this study was to further validate ColDx using formalin-fixed, paraffin-embedded specimens collected as part of the Alliance phase III trial, C9581. Patients and Methods C9581 evaluated edrecolomab versus observation in patients with stage II CC and reported no survival benefit. Under an initial case-cohort sampling design, a randomly selected subcohort (RS) comprised 514 patients from 901 eligible patients with available tissue. Forty-nine additional patients with recurrence events were included in the analysis. Final analysis comprised 393 patients: 360 RS (58 events) and 33 non-RS events. Risk status was determined for each patient by ColDx. The Self-Prentice method was used to test the association between the resulting ColDx risk score and RFI adjusting for standard prognostic variables. Results Fifty-five percent of patients (216 of 393) were classified as high risk. After adjustment for prognostic variables that included mismatch repair (MMR) deficiency, ColDx high-risk patients exhibited significantly worse RFI (multivariable hazard ratio, 2.13; 95% CI, 1.3 to 3.5; P < .01). Age and MMR status were marginally significant. RFI at 5 years for patients classified as high risk was 82% (95% CI, 79% to 85%), compared with 91% (95% CI, 89% to 93%) for patients classified as low risk. Conclusion ColDx is associated with RFI in the C9581 subsample in the presence of other prognostic factors, including MMR deficiency. ColDx could be incorporated with the traditional clinical markers of risk to refine patient prognosis.
Effect of Interval (7 or 11 weeks) Between Neoadjuvant Radiochemotherapy and Surgery on Complete Pathologic Response in Rectal Cancer: A Multicenter, Randomized, Controlled Trial (GRECCAR-6)
Authors: Lefevre Jérémie H. , Mineur Laurent , Kotti Salma , Rullier Eric , Rouanet Philippe , de Chaisemartin Cécile , Meunier Bernard , Mehrdad Jafari , Cotte Eddy , Desrame Jérome , Karoui Mehdi , Benoist Stéphane , Kirzin Sylvain , Berger Anne , Panis Yves , Piessen Guillaume , Saudemont Alain , Prudhomme Michel , Peschaud Frédérique , Dubois Anne , Loriau Jérome , Tuech Jean-Jacques , Meurette Guillaume , Lupinacci Renato , Goasgen Nicolas , Parc Yann , Simon Tabassome , Tiret Emmanuel 
Published: July 2016

Purpose A pathologic complete response (pCR; ypT0N0) of a rectal tumor after neoadjuvant radiochemotherapy (RCT) is associated with an excellent prognosis. Several retrospective studies have investigated the effect of increasing the delay after RCT. The aim of this study was to evaluate the effect of increasing the interval between the end of RCT and surgery on the pCR rate. Methods GRECCAR6 was a phase III, multicenter, randomized, open-label, parallel-group controlled trial. Patients with cT3/T4 or Tx N+ tumors of the mid or lower rectum who had received RCT (45 to 50 Gy with fluorouracil or capecitabine) were included. Patients were randomly included in the 7-week or the 11-week (11w) group. Primary end point was the pCR rate defined as a ypT0N0 specimen (NCT01648894). Results A total of 265 patients from 24 centers were enrolled between October 2012 and February 2015. The majority of the tumors were cT3 (82%). After RCT, surgery was not performed in nine patients (3.4%) because of the occurrence of distant metastasis (n = 5) or other reasons. Two patients underwent local resection of the tumor scar. A total of 47 (18.6%) specimens were classified as ypT0 (four had invaded lymph nodes [8.5%]). The primary end point (ypT0N0) was not different (7 weeks: 20 of 133, 15.0% v 11w: 23 of 132, 17.4%; P = .5983). Morbidity was significantly increased in the 11w group (44.5% v 32%; P = .0404) as a result of increased medical complications (32.8% v 19.2%; P = .0137). The 11w group had a worse quality of mesorectal resection (complete mesorectum [I] 78.7% v 90%; P = .0156). Conclusion Waiting 11 weeks after RCT did not increase the rate of pCR after surgical resection. A longer waiting period may be associated with higher morbidity and more difficult surgical resection.
Rupture and the Maintenance of Indigenous Alterity: Crises, Borders, and Race in Ecuador, 1941–2008
Authors: Viatori Maximilian 
Published: July 2016

Abstract
This article examines how narratives of historical rupture and crisis maintain, rather than upset, dominant racial hierarchies. An analysis of elite narrations of Ecuador’s border conflicts with Peru and Colombia between 1941 and 2008 demonstrates how such crisis narratives functioned as ongoing strategies for reinforcing indigenous peoples’ alterity within the Ecuadorian nation. Specifically, white-mestizo elites discursively framed these crises as historical breaks that necessitated new visions of the country’s future. Rather than bring histories of racial inequality to the fore, such crisis narratives obscured them and sought to prevent meaningful considerations of enduring colonial politics in Ecuador.
Two types of dominant male cichlid fish: behavioral and hormonal characteristics
Authors: Alcazar Rosa M. , Becker Lisa , Hilliard Austin T. , Kent Kai R. , Fernald Russell D. 
Published: July 2016

ABSTRACT
Male African cichlid fish, Astatotilapia burtoni, have been classified as dominant or subordinate, each with unique behavioral and endocrine profiles. Here we characterize two distinct subclasses of dominant males based on types of aggressive behavior: (1) males that display escalating levels of aggression and court females while they establish a territory, and (2) males that display a stable level of aggression and delay courting females until they have established a territory. To profile differences in their approach to a challenge, we used an intruder assay. In every case, there was a male-male confrontation between the resident dominant male and the intruder, with the intruder quickly taking a subordinate role. However, we found that dominant males with escalating aggression spent measurably more time attacking subordinates than did dominant males with stable aggression that instead increased their attention toward the females in their tank. There was no difference in the behavior of intruders exposed to either type of dominant male, suggesting that escalating aggression is an intrinsic characteristic of some dominant males and is not elicited by the behavior of their challengers. Male behavior during the first 15 min of establishing a territory predicts their aggressive class. These two types of dominant males also showed distinctive physiological characteristics. After the intruder assay, males with escalating aggression had elevated levels of 11-ketotestosterone (11-KT), testosterone, estradiol, and cortisol, while those with stable aggression did not. These observations show that the same stimulus can elicit different behavioral and endocrine responses among A. burtoni dominant males that characterize them as either escalating or stable aggressive types. Our ability to identify which individuals within a population have escalating levels of aggressive responses versus those which have stable levels of aggressive responses when exposed to the same stimulus, offers a potentially powerful model for investigating the underlying molecular mechanisms that modulate aggressive behavior.
Modeling Multimodal Continuous Heterogeneity in Conjoint Analysis—A Sparse Learning Approach
Authors: Chen Yupeng , Iyengar Raghuram , Iyengar Garud 
Published: July 2016

Consumers’ preferences can often be represented using a multimodal continuous heterogeneity distribution. One explanation for such a preference distribution is that consumers belong to a few distinct segments, with preferences of consumers in each segment being heterogeneous and unimodal. We propose an innovative approach for modeling such multimodal distributions that builds on recent advances in sparse learning and optimization. We apply the model to conjoint analysis where consumer heterogeneity plays a critical role in determining optimal marketing decisions. Our approach uses a two-stage divide-and-conquer framework, where we first divide the consumer population into segments by recovering a set of candidate segmentations using sparsity modeling, and then use each candidate segmentation to develop a set of individual-level heterogeneity representations. We select the optimal individual-level heterogeneity representation using cross-validation. Using extensive simulation experiments and three field data sets, we show the superior performance of our sparse learning model compared to benchmark models including the finite mixture model and the Bayesian normal component mixture model.Data, as supplemental material, are available at http://dx.doi.org/10.1287/mksc.2016.0992 .
Channel Integration, Sales Dispersion, and Inventory Management
Authors: Gallino Santiago , Moreno Antonio , Stamatopoulos Ioannis 
Published: July 2016

We study the effects of the introduction of cross-channel functionalities on the overall sales dispersion of retailers and the implications of these effects for inventory management. To do that, we analyze data from a leading U.S. retailer who introduced a “ship-to-store” (STS) functionality that allows customers to ship products to their local store free of charge when those products are not available in their local store. Based on the fact that stores prioritize carrying products for which local demand is high, we test the hypothesis that introducing the STS functionality increased the retailer’s overall sales dispersion. We find that, on average, the contribution of the 90% lowest-selling products to total sales increased by 0.75 percentage points, increasing sales dispersion. Calibrating conventional inventory-ordering models, we show that to respond optimally to the observed increase in dispersion, the retailer would need to increase its cycle and safety inventories by approximately 2.7%. Our paper points out the effect of an increasingly important retail phenomenon (channel integration) on a key factor for inventory management (sales dispersion). This paper was accepted by Vishal Gaur, operations management.
Investor Horizon and the Life Cycle of Innovative Firms: Evidence from Venture Capital
Authors: Barrot Jean-Noël 
Published: July 2016

This paper studies whether and how the contractual horizon of venture capital funds affects their investments in innovative firms. I find that funds with a longer remaining horizon select younger companies at an earlier stage of their development, which grow their patent stock significantly more than companies financed by funds with a shorter horizon. The sensitivity of investment decisions to horizon is stronger among experienced venture capital firms, who allocate investments across a larger number of fund vintages. Finally, I find that the interaction of funds’ fixed horizon with their option-like compensation structure affects their investment decisions: when early performance has been high, fund managers target less innovative companies. These findings shed light on the drivers of venture capital investment decisions and on their implications for the type of companies that receive venture capital financing. This paper was accepted by Gustavo Manso, finance.
Debates teóricos no campo das Relações Internacionais na China | Theoretical Debates in the Field of International Relations in China
Authors: Montenegro Renan Holanda 
Published: July 2016

Este trabalho tem o objetivo de apresentar um panorama sobre a evolução do campo das Relações Internacionais na China e os debates recentes em torno do desenvolvimento de uma escola teórica autônoma que incorpore elementos da cultura chinesa. Neste debate, duas principais correntes têm se posicionado em lados opostos: a “Chinese School” e a “Tsinghua School”. O presente artigo descreve as diferenças entre essas escolas e discute as contribuições de cada uma para a elaboração de uma teoria chinesa das Relações Internacionais.ABSTRACTThis paper aims to present an overview about the evolution of the field of International Relations in China and the recent debates on the development of an autonomous theoretical school that incorporates elements of Chinese culture. In this debate, two main trends have positioned themselves on opposite sides: "Chinese School" and "Tsinghua School". This article describes the differences between these schools and discusses the contributions of each to the development of a Chinese theory of International Relations. Palavras-chave: China; Teoria; Relações Internacionais.Keywords: China; Theory; International Relations. DOI: 10.12957/rmi.2015.18387 Recebido em 28 de agosto de 2015 / Aceito em 01 de dezembro de 2015.Received on August 28, 2015 / Accepted December 01, 2015.
How to measure interconnectedness between banks, insurers and financial conglomerates
Authors: Hauton Gaël , Héam Jean-Cyprien 
Published: July 2016

Abstract
Financial institutions’ interconnectedness is a key component of systemic risk. However there is still no consensus on its measurement.
Using a unique database of network of exposures of French financial institutions, we compare three strategies to measure interconnectedness: closeness of exposure distributions, identification of core-periphery structure and contagion models. The closeness of exposure distributions is adequate to identify outlier institutions. The “core-periphery” structure, usually applied to banking network, is still valid with insurance companies. However this approach is not immune to size effect. This result contrasts with previous analyses where size was not accounted for. Contagion-based stress-tests are the best suited to capture institutions’ systemic fragility, emphasizing their importance as a supervisory tool.
Regulation of mitotic spindle orientation: an integrated view
Authors: di Pietro Florencia , Echard Arnaud , Morin Xavier 
Published: July 2016

AbstractMitotic spindle orientation is essential for cell fate decisions, epithelial maintenance, and tissue morphogenesis. In most animal cell types, the dynein motor complex is anchored at the cell cortex and exerts pulling forces on astral microtubules to position the spindle. Early studies identified the evolutionarily conserved Gαi/LGN/NuMA complex as a key regulator that polarizes cortical force generators. In recent years, a combination of genetics, biochemistry, modeling, and live imaging has contributed to decipher the mechanisms of spindle orientation. Here, we highlight the dynamic nature of the assembly of this complex and discuss the molecular regulation of its localization. Remarkably, a number of LGN‐independent mechanisms were described recently, whereas NuMA remains central in most pathways involved in recruiting force generators at the cell cortex. We also describe the emerging role of the actin cortex in spindle orientation and discuss how dynamic astral microtubule formation is involved. We further give an overview on instructive external signals that control spindle orientation in tissues. Finally, we discuss the influence of cell geometry and mechanical forces on spindle orientation.
Conceptos de la identidad cultural de estudiantes hispanounidenses
Authors: Monge Acuña Virginia 
Published: July 2016

En este artículo se presenta una reflexión acerca del derecho a la identidad cultural; un concepto que en la actualidad genera consideraciones más allá de los contextos territoriales y temporales a la vez que enfatiza caracterizaciones particulares de diferenciación. Se discute el concepto de identidad cultural como derecho de los estudiantes hispanounidenses y la estrecha relación de la lengua de herencia con esta. Además, el artículo presenta los conceptos de reconstrucción de la dignidad y la pertenencia referentes a la identidad cultural, provenientes directamente de las voces de estudiantes hispanounidenses de la escuela secundaria. Por tanto, se concluye que en este proceso, el fortalecimiento de la lengua de herencia posee un rol indispensable.
Alberto Patishtán Gómez: Radiografía de un indulto tardío
Authors: Muñoz Vargas Osvaldo Antonio 
Published: July 2016

El autor muestra el insólito caso de Alberto Patishtán Gómez (Chiapas, México 2000), en cual presenta cronológicamente los hechos que se llevaron a cabo en el paraje Las Lagunas de Las Limas, Municipio de Simojovel. La importancia del caso se da al sobreestimar el relieve de violaciones de proceso en derechos humanos por sobre el trasfondo del derecho penal. En este caso específico, el autor pretende analizarlo desde una perspectiva puramente política, dejando de lado cualquier matiz antropológico de fondo en el cual, ante una relectura, se podría inferir fácilmente que hubo discriminación étnica
Reapropiación del conocimiento y descolonización: el acceso abierto como proceso de acción política del sur
Authors: Aguado-López Eduardo , Vargas Arbeláez Esther Juliana 
Published: July 2016

<p>En este artículo se analiza la idea de que el modelo de comunicación científica dominante entraña una forma de colonialidad del saber, en los términos del grupo de científicossociales latinoamericanos, de finales del siglo pasado, conformado por A. Escobar, E. Dussel, S. Castro-Gómez, entre otros. Esta forma de colonialidad del saber se puede subvertir con el fortalecimiento de la práctica de circulación del conocimiento denominada acceso abierto (AA). El estudio sigue un proceder analítico, mediante la descripción del panorama de la producción científica de América Latina y el Caribe. Eneste panorama, se aprecia el problema que representa la evaluación del quehacer científico latinoamericano a partir de ciertos estándares, y su consecuente subrrepresentación en bases de datos, como el Journal Citation Report (JCR) y elScientific Journal Ranking (SJR). Con esta descripción, se revisa la presencia latinoamericana de las ciencias sociales en el acervo que alberga SCIELO y Redalyc. Este estado de cosas se analiza, posteriormente, a la luz de un aparato teórico construido entorno a dos categorías: dispositivo, en la versión de Agamben, en el artículo del mismo nombre, y descolonialidad del saber. Estos dos elementos teóricos aportan a la comprensión de un horizonte político del camino del acceso abierto en América Latina y el Caribe, ya que —esta es la conclusión a la que apunta el texto— esta práctica se perfila en nuestra región como una apuesta política para una descolonización y reapropiación delconocimiento, en el sentido de la filosofía política italiana contemporánea. Lo anterior porque permite el acceso a los productos de investigación financiados públicamente, el“retorno” de la producción científica y, especialmente, la reconsideración de formas de valoración de la ciencia.</p>