bluuebunny/crossref_metadata_2025_split huggingface dataset:
L’ épreuve de la retraite Transformations sociétales, expériences individuelles
Authors: Caradec Vincent 
Published: April 2017

En se fondant sur une revue de la littérature ainsi que sur des enquêtes par entretiens semi-directifs réalisées, depuis une vingtaine d’années, auprès de jeunes retraités, cet article étudie les deux facettes de l’« épreuve » de la retraite, sociétale tout d’abord, individuelle ensuite. Dans un premier temps, il propose un survol socio-historique des transformations de la retraite et distingue les trois représentations sociales dominantes qui lui ont successivement été associées : le repos, les loisirs, le « vieillissement actif ». Dans un second temps, il décrit la diversité des expériences individuelles de la retraite dont il examine différentes dimensions : la question du « choix » de la retraite et la reconstruction identitaire qui s’engage alors, la dimension financière, la dimension conjugale, le face-à-face avec son vieillissement.
La retraite : une catégorie relevant du contexte social
Authors: Carreteiro Teresa Cristina , Pinto Bruna Oliveira 
Published: April 2017

Cet article montre que les significations attachées à la retraite sont fondamentales et liées à l’articulation des champs psychique, social, politique, économique et juridique. La retraite peut être considérée comme un non-événement car prévisible et ne remettant pas en cause le cours de la vie ou, au contraire, comme une catégorie biographique dans la mesure où elle peut avoir une force de rupture. L’article s’appuie sur une recherche dans laquelle sept professeurs en psychologie clinique brésiliens sont interviewés, trois relevant du secteur public et quatre provenant du secteur privé, dont deux d’universités sans complément de retraite et deux d’universités prévoyant un plan de retraite. Tous les enseignants soulignent l’intérêt porté à leur travail. Néanmoins, les significations données à la retraite sont fort différentes selon les cas. Il y a toutefois un point commun : tous continuent à travailler après leur retraite. Enfin, l’article se demande si la retraite constitue ou non un événement biographique.
Travail, vieillissement et retraite : un point de vue philosophique
Authors: Hamraoui Éric 
Published: April 2017

Penser le statut de l’expérience de vie de la retraite dans le contexte des transformations en cours dans le monde du travail est l’objet de la présente contribution. Douée d’une potentialité créatrice sur les plans individuel et social, et libératrice des contraintes de la production, la « vie de retraite » (L. Sève) constitue une réalité dissidente du point de vue de la rationalité néolibérale. Celle-ci dénie, en effet, la continuité générative des temps de la vie et la complexité anthropologique en réduisant le sujet à un « espace de compétition » (P. Dardot et C. Laval). La prise d’un nouveau point de départ, dont la retraite est l’occasion, constitue une réplique aux échos fantômes du sentiment de dette généré par la nouvelle organisation de la production et à l’inquiétude ressentie face au déploiement de la brutalité rationnelle expulsant l’individu du lieu de vie et de pensée que constitue le travail.
La « fausse justification » : le mécanisme au fondement des rivalités excessives
Authors: Mauroy Hervé 
Published: April 2017

Pour Jon Elster, les phénomènes sociaux doivent être expliqués non pas en recourant à la théorie du choix rationnel, mais en élucidant des mécanismes essentiellement psychologiques. Cet article vise à exposer l’un d’entre eux : la fausse justification. Celui-ci a été annoncé par les grands moralistes des xvii e et xviii e siècles, puis spécifié sur un mode exalté par Friedrich Nietzsche. Surtout, il a été analysé en profondeur par un psychologue trop peu connu inspiré par la philosophie : Paul Diel. La fausse justification est à l’origine des rivalités trop exacerbées.
The Asymptotics of the Higher Dimensional Reidemeister Torsion for Exceptional Surgeries Along Twist Knots
Authors: Tran Anh T. , Yamaguchi Yoshikazu 
Published: April 2017

AbstractWe determine the asymptotic behavior of the higher dimensional Reidemeister torsion for the graph manifolds obtained by exceptional surgeries along twist knots. We show that all irreducible SL2()-representations of the graph manifold are induced by irreducible metabelian representations of the twist knot group. We also give the set of the limits of the leading coeõcients in the higher dimensional Reidemeister torsion explicitly.
A Characterization of C*-normed Algebras via Positive Functionals
Authors: Haralampidou Marina , Oudadess Mohamed , Palacios Lourdes , Signoret Carlos 
Published: April 2017

AbstractWe give a characterization of C*-normed algebras, among certain involutive normed ones. This is done through the existence of enough specific positive functionals. The same question is also examined in some non normed (topological) algebras.
Effect of short-term consumption bitter apricot seeds on the body composition in healthy population
Authors: Kopčeková Jana , Kolesárová Anna , Gažarová Martina , Lenártová Petra , Mrázová Jana , Kolesárová Adriana 
Published: April 2017

The distribution of fat in different areas of the body is important since accumulation of fat within the abdominal cavity represents a much more severe cardiovascular risk than accumulation in subcutaneous adipose tissues. Apricot seeds contain a wide variety of bioactive compounds and that consumption can decrease blood pressure and total blood cholesterol levels, fight oxidative stress and maintain body weight. The aim of the study was to analyse body composition: body fat mass (BFM), fat free mass (FFM), skeletal muscle mass (SMM), body fat percentage (%BFM), visceral fat area (VFA), total body water (TBW) - intracellular water (ICW) and extracellular water (ECW) and to evaluate the changes that occur after 6-weeks consumption of bitter apricot seeds. The study group finally consisted of 34 healthy adults volunteers (21 females and 13 males). Volunteers were recruited from the general population of Slovakia. Respondents were 23 - 65 years old, where the average age of women was 40.65 ±11.31 years and the average age of men was 36.91 ±9.98 years. All participants were asked to consume 60 mg.kg-1 of body weight of bitter apricot seeds daily during 6 weeks. Body composition was diagnosed by multi-frequency bioelectrical impedance analysis (MFBIA) by InBody 720 (Biospace Co., Korea), which measures the total impedance at frequencies of 1, 5, 50, 100, 500, 1000 kHz. At baseline mean body weight was 85.78 ±14.66 and 62.84 ±12.19 kg in the male and female participants, respectively. After 6 weeks of consumation we observed non-significant decreasing of mean body weight. The mean BFM was 19.25 ±8.81 kg in the male group and 19.47 ±7.21 kg in the female group. After six weeks, BFM decreased non-significantly (on average 0.5 kg) in both groups. The mean FFM at baseline was 43.37 ±5.98 and 66.54 ±7.98 kg in the female and male participants, respectively. The statistical analysis confirmed that the increase of FFM (43.37 ±5.98 kg to 43.56 ±5.80 kg) in the female were statistically significant (p <0.05). VFA was greater in the men (82.04 ±39.82 cm2 at baseline and 78.65 ±39.79 cm2 after 6 weeks) comparison to women (79.82 ±29.03 cm2 at baseline and 78.29 ±29.90 cm2 after 6 weeks). The mean of TBW in males before the start of study was 48.78 ±5.77 kg and 47.88 ±5.57 kg after 6 weeks of consumption. The results of study show the small weight loss in the both group. Therefore, the results from this study indicate that daily consumption of bitter apricot seeds produce measurable health benefits, but further studies are also required.
Hormonal changes in spring barley after triazine herbicide treatment and its mixtures of regulators of polyamine biosynthesis
Authors: Trebichalský Pavol , Tóth Tomáš , Bajčan Daniel , Harangozo Ľuboš , Vollmannová Alena 
Published: April 2017

Plants adapt to abiotic stress by undergoing diverse biochemical and physiological changes that involve hormone-dependent signalling pathways. The effects of regulators of polyamine biosynthesis can be mimicked by exogenous chemical regulators such as herbicide safeners, which not only enhance stress tolerance but also confer hormetic benefits such as increased vigor and yield. The phytohormones, abscisic acid (ABA) and auxin (IAA) play key roles in regulating stress responses in plants. Two years pot trials at Slovak University of agriculture Nitra were carried out with analyses of contents of plant hormones in spring barley grain of variety Kompakt: indolyl-acetic acid (IAA) and abscisic acid (ABA), after exposing of tested plants to herbicide stress, as well as the possible decrease of these stress factors with application of regulators of polyamine synthesis was evaluated. At 1st year in spring barley grain after application of solo triazine herbicide treatment in dose 0,5 L.ha-1 an increase of all analyzed plant hormones was observed and contrary, at 2nd year there was the decrease of their contents. From our work there is an obvious influence of herbicide stress induced by application of certain dose of triazine herbicide at 1st year. Expect of the variant with mixture of triazine herbicide (in amount of 0,5 L.ha-1) and 29,6 g.ha-1 DAB, at this year all by us applied regulators of polyamine synthesis reduced the level of both plant hormones. Higher affect of stress caused by enhanced content of soluble macroelements in soil where the plants of barley were grown was observed next year. Soil with increased contents of macronutrients (mg.kg-1): N30.7 + P108.3 + K261.5 + Mg604.2 had reducing effect on contents of plant hormones in barley grain at variant treated with solo triazine herbicide (in dose at 0,5 L.ha-1) in comparison to control variant. The mixtures of regulators of polyamine synthesis reduced the contents of IAA only in comparison to control variant. Decline in amount of ABA in barley grain was observed only after treatment with GABA, also in comparison to variant treated with water. Other mixtures of morphoregulators in combination with herbicide had not strong influence on contents of tested plant hormones in barley grain of variety Kompakt.
The impact of varieties, ripeness, and heat treatment on the retention of vitamin C and content of soluble solids in sweet pepper
Authors: Valší­ková Magdaléna , Rehuš Marián , Komár Patrik , Paulen Oleg 
Published: April 2017

In the three-year field trial we have grown six varieties of sweet peppers and we observed a change in the content of soluble solids and vitamin C during aging and after heat treatment with the sterilization. The highest content of soluble solids was found in peppers collected in botanical maturity, where the average was 5.82% in 2012, 6.52 in 2013 and 6.13 in 2014. Lower average, we measured in the intermediate maturity, 4.25 in 2012, 5.2% in 2013 and 4.73% in 2014. The lowest soluble solids content was recorded for fruit harvested in technical ripeness, only 3.57% in 2012, 4.25% in 2013 and 4.10% in 2014. In the technical maturity we determined the average value of vitamin C by the years between 90.98 mg.100 g-1 and 103.86 mg.100 g-1. The average in vitamin C content in fresh pepper fruits of intermediate maturity was ranging from 108.81 to 124.65 mg.100 g-1. The highest average values of vitamin C were at the botanical maturity from 171.42 to 188.30 mg.100 g-1. In the average of years and times of harvest it was found that the variety ´PCR´ and ´Slovakia´ had the first and second place in content of vitamin C (146.10 mg.100 g-1 - ´PCR´ and 143.72 mg.100-1 - ´Slovakia´). The least vitamin C was observed in a variety ´Katrena´ (120.80 mg.100 g-1). For six varieties we have found that in technical maturity retained after sterilization on average 34.0% of vitamin C, in an intermediate maturity 47.16% and 42.10% of botanical maturity. Vitamin C was the highest in sterilized pepper variety of ´Slovakia´ and ´PCR´ in all three stage of maturity. The results show that the pepper is an excellent reservoir of vitamin C, not only in c fresh state, but also after heat treatment.
Billijke vergoeding: over karakter, begroting en artikel 6 EVRM
Authors: Bij de Vaate Vivian , Kruit Pascal 
Published: April 2017

Billijke vergoeding: over karakter, begroting en artikel 6 EVRM
De billijke vergoeding heeft sinds de invoering van de Wet werk en zekerheid een prominente plaats gekregen in het ontslagrecht. In deze bijdrage voorzien de auteurs de billijke vergoeding van een nadere analyse. Aan bod komen onder andere het karakter van de billijke vergoeding, denkbare begrotingsmethodieken, jurisprudentieanalyse en een kanttekening vanuit het oogpunt van artikel 6 EVRM bij de (mede) punitieve billijke vergoeding.
Stability-Indicating UPLC Method for the Estimation of Nadifloxacin, Terbinafine Hydrochloride, Mometasone Furoate, Methyl Paraben, and Propyl Paraben in Topical Pharmaceutical Dosage Form
Authors: Bhosale Dileep M , Nikalje Anna Pratima G 
Published: April 2017

Abstract
A novel and simple ultra-performance LC method was developed for the estimation of nadifloxacin (NAD), terbinafine hydrochloride (TBH), mometasone furoate (MMF), methyl paraben (MP), and propyl paraben (PP) in a topical pharmaceutical dosage formulation. The analysis was carried out on a Waters Acquity UPLC ethylene bridged hybrid C18 column (50 × 2.1 mm, 1.7 μm) with a flow rate of 0.4 mL/min ingradient mode at a wavelength of 255 nm. Elution of all components was achieved within 9 min. The retention times of MP, NAD, PP, TBH, and MMF were observedat 1.5, 2.6, 3.4, 6.0, and 6.9 min, respectively. The proposed method was validated per current International Conference on Harmonization guidelines for specificity, precision, linearity, accuracy, range, LOD, LOQ, robustness, filter paper interference, and solution stability parameters. A complete method studywas performed to determine the stability-indicating nature of the developed method.
Design of a Sensitive and Selective Electrochemical Aptasensor for the Determination of the Complementary cDNA of miRNA-145 Based on the Intercalation and Electrochemical Reduction of Doxorubicin
Authors: Mohamadi Maryam , Mostafavi Ali , Torkzadeh-Mahani Masoud 
Published: April 2017

Abstract
The aim of this research was the determination of a microRNA (miRNA) using a DNA electrochemical aptasensor. In this biosensor, the complementary complementary DNA (cDNA) of miRNA-145 (a sense RNA transcript) was the target strand and the cDNA of miRNA-145 was the probe strand. Both cDNAs can be the product of the reverse transcriptase-polymerase chain reaction of miRNA. The proposed aptasensor’s function was based on the hybridization of target strands with probes immobilized on the surface of a working electrode and the subsequent intercalation of doxorubicin (DOX) molecules functioning as the electroactive indicators of any double strands that formed. Electrochemical transduction was performed by measuring the cathodic current resulting from the electrochemical reduction of the intercalated molecules at the electrode surface. In the experiment, because many DOX molecules accumulated on each target strand on the electrode surface, amplification was inherently easy, without a need for enzymatic or complicated amplification strategies. The proposed aptasensor also had the excellent ability to regenerate as a result of the melting of the DNA duplex. Moreover, the use of DNA probe strands obviated the challenges of working with an RNA probe, such as sensitivity to RNase enzyme. In addition to the linear relationship between the electrochemical signal and the concentration of the target strands that ranged from 2.0 to 80.0 nM with an LOD of 0.27 nM, the proposed biosensor was clearly capable of distinguishing between complementary (target strand) and noncomplementary sequences. The presented biosensor was successfully applied for the quantification of DNA strands corresponding to miRNA-145 in human serum samples.
Simultaneous Determination of Volatile Organic Compounds in Commercial Alcoholic Beverages by Gas Chromatography with Flame Ionization Detection
Authors: Kim Hyung Min , Yang Gun , Kim Jung Yoon , Yoon Sang Jun , Shin Byong-kyu , Lee Jeongmi , Park Jeong Hill , Kwon Sung Won 
Published: April 2017

Abstract
A simple and fast method was developed for the determination of volatile organic compounds in alcoholic beverages. Eleven volatile organic compounds (acetaldehyde, methanol, 2-propanol, tert-butanol, 1-propanol, ethyl acetate, 2-butanol, isobutanol, 1-butanol, 3-methyl-1butanol, and 2-methyl-1-butanol) in alcoholic beverages were analyzed with a simple direct-injection method using GC with flame ionization detection. These compounds should be monitored in the QC of production processes because they are detrimental to human health. The method was validated with four types of alcoholic beverages (beers, fruit wines, rice wines, and spirits) to confirm the versatility of the method. Linearity showed r2 values from 0.9986 to 0.9995, with LODs ranging from 0.010 to 1.000 mg/L. Precision and accuracy showed acceptable results, proving the effectiveness of the method. The developed method was applied to 40 commercial samples representing the four types of alcoholic beverages, and principal component analysis was performed to determine profiles of the volatile organic compounds, depending on the type of alcoholic beverage.
Deep learning‐based analysis of EGFR mutation prevalence in lung adenocarcinoma H&E whole slide images
Authors: Park Jun Hyeong , Lim June Hyuck , Kim Seonhwa , Kim Chul‐Ho , Choi Jeong‐Seok , Lim Jun Hyeok , Kim Lucia , Chang Jae Won , Park Dongil , Lee Myung‐won , Kim Sup , Park Il‐Seok , Han Seung Hoon , Shin Eun , Roh Jin , Heo Jaesung 
Published: October 2024

AbstractEGFR mutations are a major prognostic factor in lung adenocarcinoma. However, current detection methods require sufficient samples and are costly. Deep learning is promising for mutation prediction in histopathological image analysis but has limitations in that it does not sufficiently reflect tumor heterogeneity and lacks interpretability. In this study, we developed a deep learning model to predict the presence of EGFR mutations by analyzing histopathological patterns in whole slide images (WSIs). We also introduced the EGFR mutation prevalence (EMP) score, which quantifies EGFR prevalence in WSIs based on patch‐level predictions, and evaluated its interpretability and utility. Our model estimates the probability of EGFR prevalence in each patch by partitioning the WSI based on multiple‐instance learning and predicts the presence of EGFR mutations at the slide level. We utilized a patch‐masking scheduler training strategy to enable the model to learn various histopathological patterns of EGFR. This study included 868 WSI samples from lung adenocarcinoma patients collected from three medical institutions: Hallym University Medical Center, Inha University Hospital, and Chungnam National University Hospital. For the test dataset, 197 WSIs were collected from Ajou University Medical Center to evaluate the presence of EGFR mutations. Our model demonstrated prediction performance with an area under the receiver operating characteristic curve of 0.7680 (0.7607–0.7720) and an area under the precision‐recall curve of 0.8391 (0.8326–0.8430). The EMP score showed Spearman correlation coefficients of 0.4705 (p = 0.0087) for p.L858R and 0.5918 (p = 0.0037) for exon 19 deletions in 64 samples subjected to next‐generation sequencing analysis. Additionally, high EMP scores were associated with papillary and acinar patterns (p = 0.0038 and p = 0.0255, respectively), whereas low EMP scores were associated with solid patterns (p = 0.0001). These results validate the reliability of our model and suggest that it can provide crucial information for rapid screening and treatment plans.
Fundamental study of damping models with enhanced frequency independence in nonlinear seismic response analysis
Authors: Ota Akira , Nakamura Naohiro , Nabeshima Kunihiko , Mogi Yoshihiro , Kawabata Masafumi 
Published: October 2024

AbstractCausal hysteretic damping, extended Rayleigh damping, and uniform damping models exhibit frequency‐independent damping ratios over a wide frequency range. However, several points remain unclear regarding their applicability to inelastic problems. Therefore, in this study, to compare the vibration characteristics of these damping models, analyses are performed by inputting white noise into simple models with various natural frequencies. Results confirm that these damping models are frequency‐independent even under inelastic conditions. Further, the causal hysteretic and extended Rayleigh damping models have the same computation order as that of conventional Rayleigh damping and can therefore be calculated in approximately the same time.
Comparison of translation algorithms in determining maximum allowable CTV shifts for Real‐Time Gated Proton Therapy (RGPT) robustness evaluation in prostate cancers
Authors: Lee James Kuan Huei , Lew Kah Seng , Koh Calvin Wei Yang , Lee James Cheow Lei , Bettiol Andrew A. , Park Sung Yong , Tan Hong Qi 
Published: October 2024

AbstractIntroductionReal‐Time Gated Proton Therapy (RGPT) is an active motion management technique that utilizes treatment gating and tumor tracking via fiducial markers. When performing RGPT treatment for prostate cancer, it is essential to account for the CTV displacement relative to the body in the clinical workflow. The workflow at the National Cancer Centre Singapore (NCCS) includes bone matching via CT‐CBCT images, followed by fiducial matching via pulsed fluoroscopy (soft tissue matching), and finally, a robustness evaluation procedure to determine if the difference is within an allowable tolerance. In this study, we compare two CTV translation methods for robustness evaluation: (1) an in‐house translation algorithm and (2) the RayStation “simulate organ motion” Deformable image registration (DIR) algorithm.MethodsNine RGPT prostate patient plans with CTV volumes ranging from 17.1 to 96.72 cm2 were included in this study. An in‐house translation algorithm and “simulate organ motion” DIR RayStation algorithm were used to generate CTV shifts along R‐L, I‐S, and P‐A axes between 10 mm at 2 mm steps. At each step, dose metrics, which include CTV Dmax, CTV D95%, and CTV D98%, were extracted and used as comparative metrics for CTV target coverage and hot spot evaluation.ResultsAcross all axes, there were no statistically significant differences between the two algorithms for all three dose metrics: CTV Dmax (P = 0.92, P = 0.91, and P = 0.47), CTV D95% (P = 0.97, P = 0.22, and P = 0.33), and CTV D98% (P = 0.85, P = 0.33, and P = 0.36). Further, the in‐house translation algorithm evaluation time was less than 10 s, two orders of magnitude faster than the DIR algorithm.ConclusionOur results demonstrate that the simpler in‐house algorithm performs equivalently to the realistic DIR algorithm when simulating CTV motion in prostate cancers. Furthermore, the in‐house algorithm completes the robustness evaluation two orders of magnitude faster than the DIR algorithm. This significant reduction in evaluation time is crucial especially when preparatory time efficiency is of paramount importance in a busy clinic.