bluuebunny/crossref_metadata_2025_split huggingface dataset:
CT Texture Analysis of Perihilar Cholangiocarcinoma—Associations With Tumor Grading, Tumor Markers and Clinical Outcome
Authors: Leonhardi Jakob , Sabanov Arsen , Höhn Anne Kathrin , Sucher Robert , Seehofer Daniel , Mehdorn Matthias , Schnarkowski Benedikt , Ebel Sebastian , Denecke Timm , Meyer Hans‐Jonas 
Published: September 2024

ABSTRACTBackgroundTexture analysis derived from computed tomography (CT) may provide clinically relevant imaging biomarkers associated with tumor histopathology. Perihilar cholangiocarcinoma is a malignant disease with an overall poor prognosis.AimsThe present study sought to elucidate possible associations between texture features derived from CT images with grading, tumor markers, and survival in extrahepatic, perihilar cholangiocarcinomas tumors.MethodsThis retrospective study included 22 patients (10 females, 45%) with a mean age of 71.8 ± 8.7 years. Texture analysis was performed using the free available Mazda software. All tumors were histopathologically confirmed. Survival and clinical parameters were used as primary study outcomes.ResultsIn discrimination analysis, “S(1,1)SumVarnc” was statistically significantly different between patients with long‐term survival and nonlong‐term survival (mean 275.8 ± 32.6 vs. 239.7 ± 26.0, p = 0.01). The first‐order parameter “skewness” was associated with the tumor marker “carcinoembryonic antigen” (CEA) (r = −0.7, p = 0.01). A statistically significant correlation of the texture parameter “S(5,0)SumVarnc” with tumor grading was identified (r = −0.6, p < 0.01). Several other texture features correlated with tumor markers CA‐19‐9 and AFP, as well as with T and N stage of tumors.ConclusionSeveral texture features derived from CT images were associated with tumor characteristics and survival in patients with perihilar cholangiocarcinomas. CT texture features could be used as valuable novel imaging markers in clinical routine.
Living With a New Normal: Self‐Identities of Women With Breast Cancer in Nigeria
Authors: Adaranijo Aisha Abimbola , Amzat Jimoh , Abdulrahman Dejo , Kanmodi Kehinde Kazeem 
Published: September 2024

ABSTRACTBackgroundBreast cancer is the most prevalent cancer for women in Nigeria, representing 25% of all cancers in women. How do women self‐identify with the new realities of living with breast cancer before, during and after treatment?AimsThis study aims to examine the self‐identities of 22 women with breast cancer in Nigeria.MethodsThe paper relies on grounded theory research method to collect data, analyse and capture the processes of self‐identity formation.ResultsThe qualitative data analysis reveals the basic social process within symbolic interactionism that describes how breast cancer survivors perceive their agency and how new self‐identities emerged from the new normal of living with breast cancer. A framework of three self‐identities emerged from the data: (1) valued self‐identity before breast cancer, (2) dependent and determined self‐identities during treatment and (3) devalued self‐identity post‐treatment.ConclusionThis study should help caregivers understand the profound perpetual psycho‐emotional impact that breast cancer has on sufferers and survivors.
Expression Characteristics, Immune Signature, and Prognostic Value of the SOCS Family Identified by Multiomics Integrative Analysis in Liver Cancer
Authors: Dong Zhitao , Dai Binghua , Wu Rui , Fang Kunpeng , Sui Chengjun , Geng Li , Yang Jiamei 
Published: September 2024

ABSTRACTBackgroundHepatocellular carcinoma (HCC) is a prevalent malignancy with a high mortality rate worldwide. Suppressor of cytokine signaling (SOCS) family members play important roles in the proliferation, metabolism, and immunity of HCC cells by regulating cytokines and growth factors. However, it remains uncertain whether the level of SOCS family members can affect the prognosis of HCC patients.AimsThis study aimed to comprehensively assess the role and mechanisms of SOCS family members in the development of HCC and to guide clinical selection.MethodsWe investigated the expression levels of SOCS family genes in HCC patients and their associations with various clinicopathological characteristics. We also utilized a public database to analyze the changes in the expression, potential functions, transcription factors, and immune invasion of SOCS family members. Additionally, we examined the prognostic value of the SOC family for HCC and its correlation with the SOC family and ferroptosis‐related genes.ResultsThis study revealed that the expression of SOCS2‐7, and CISH was downregulated in HCC. The SOCS4, SOCS5, and SOCS7 genes were associated with the clinicopathological features of HCC patients. SOCS family genes are mainly related to the PIK3R3, GHR, and TNS4 pathways. Additionally, this study revealed that STAT3, PPAR‐gamma 2, and IRF‐2 are important transcription factors that regulate SOCS family members. The expression levels of SOCS family members are closely related to immune infiltration in liver cancer. The study also indicated that SOCS2 and SOCS4 are risk‐related genes for predicting the prognosis of patients with liver cancer. Finally, this study suggested that the SOCS2 gene may be involved in the development and progression of HCC.ConclusionOur study enhances the current understanding of SOCS gene function in liver cancer and can help clinicians select appropriate drugs and predict the prognosis of HCC patients.
Reversible in situ Control over Monolayer Organization
Authors: Mukherjee Neelanjana , Blanchard G. J. 
Published: September 2024

AbstractCr2+ and Cr3+ ions are shown to mediate the formation, morphology, and organization of arachidic acid (AA) Langmuir‐Blodgett (LB) monolayers. This finding, based on cyclic voltammetry (CV), linear sweep voltammetry (LSV) and fluorescence recovery after photobleaching (FRAP) measurements, show that Langmuir monolayer formation depends on subphase pH and metal ion concentration. Following monolayer deposition on indium tin oxide (ITO), the LB monolayer organization can be modified reversibly through control of the Cr oxidation state, which has not been shown before by other monolayers formed with other divalent metal ions. The dynamics and the mobility of a chromophore (perylene) incorporated into the monolayer sense changes in Cr oxidation state‐dependent organization of the LB monolayer. Demonstrating reversible changes in monolayer organization provides an opportunity to control chemical and electron access to the interface support.
Genetic and environmental drivers of legume cover crop performance: Hairy vetch
Authors: Kucek Lisa Kissing , Muller Katherine , Martins Lais Bastos , Moore Virginia M. , Reberg‐Horton Chris , Mirsky Steven B. , Englert John , Drinkwater Laurie E. , Douglas Joel , Eagen Sarah S. , Butler Twain , Ryan Matthew R. , Casey Allen , Clark Kerry , Ehlke Nancy , Hendrickson John , Guretzky John , Johnson Holly , Archer David , McGee Rebecca J. , Ali Shahjahan , Bartow Amy , Bullard Valerie , Burke Allen N. , Barrett Richard , Bernau Christopher , Carr Brandon , Crawford Ryan , Griffin Kimberly , Inoa Esleyther Henriquez , Hillhouse Heidi , Humphrey Mathew , Smither‐Kopperl Margaret , Krogman Sarah , Lee Steven , Marion Annie , McGhee Nicholas , Silvernail Ian , Thevar Prasanna , Wayman Sandra , Wiering Nick P. , Wiggans Dustin , Riday Heathcliffe 
Published: September 2024

AbstractAmong 50 environments in the United States, we screened 35 hairy vetch (Vicia villosa Roth.) lines for traits of interest to cover cropping. We analyzed the influence of genotype, environment, and the genotype‐by‐environment interaction (G × E) on biomass, vigor, winter survival, emergence, flowering time, and nitrogen fixation. To explore how environments and G × E impacted each trait, we associated environment predictions and G × E loadings with weather and soil parameters. Environment had the largest influence on all traits, representing more than half of the variance. Environment predictions were significantly associated with weather and/or soil parameters for each trait. Biomass was associated with growing degree days, winter survival with freezing degree days without snow cover, growth stage with shortwave radiation, and emergence with soil texture. The G × E interaction was larger than genotypic variance for all traits except for winter survival and flowering time. The G × E interaction loadings were associated with soil sand content for biomass, air temperature for fall vigor and emergence, and snow cover for winter survival. Although it represented the smallest proportion of total variance, genetic effects were significant for all traits except for emergence, Ndfa, %N, and C:N. New hairy vetch breeding lines were superior to all commercially available lines for biomass and winter survival. Biomass harvest timing did not significantly change line rank, indicating that top‐performing lines can be used in diverse management systems. To select for high nitrogen contribution to subsequent crops, breeding programs can indirectly select for biomass rather than expensively evaluating symbiotic nitrogen fixation.
Inheritance of summer patch disease tolerance in hard fescue (Festuca brevipila Tracey)
Authors: Wu Shidi , Grimshaw Austin L. , Qu Yuanshuo , Bonos Stacy A. 
Published: September 2024

AbstractHard fescue (Festuca brevipila Tracey) is a cool‐season turfgrass known for exceptional performance under low‐maintenance conditions. However, it is susceptible to summer patch disease. Summer patch is a root disease caused by Magnaporthiopsis poae and Magnaporthiopsis meyeri‐festucae. The objective of this study was to investigate the inheritance of summer patch tolerance in controlled crosses of hard fescue. The experimental populations were full‐sib families created by crossing three tolerant and three susceptible parents in a diallel cross. One hundred progeny from each of the 15 crosses and reciprocals were established in a mowed spaced‐plant trial in 2017 (Trial 1) and 2019 (Trial 2). All progeny and selected parental genotypes were arranged in a randomized complete block design with four replications and inoculated with a mixture of an M. meyeri‐festucae isolate (SCR9) and an M. poae isolate (C11). The disease severity of hard fescue genotypes was assessed by visual rating during the summers of 2018, 2019, 2020, and 2021. Variation in disease responses among progeny suggests that inheritance is controlled by a few major genes. The progeny phenotypes were correlated to the parental phenotypes. The estimate of narrow‐sense heritability was 0.20 (± 0.01), while the estimate of broad‐sense heritability was 0.67 (± 0.08). The heritability estimates are modest but indicate the potential for summer patch tolerance to be improved via selection and breeding. This is the first report of heritability estimates for summer patch tolerance in any turf species. This research will help to determine the most efficient selection procedures for summer patch tolerance in hard fescue.
Association mapping of mesocotyl and coleoptile length in rice using various genome‐wide association study models
Authors: Li Rui , Wei Zhaoran , Wang Yuetao , Ma Mengjuan , Zhang Qifei , Bai Tao , Li Zichao , Zhang Zhanying , Yin Haiqing , Wang Ya 
Published: September 2024

AbstractThe mechanized direct seeding of rice (Oryza sativa L.) is a major trend nowadays. The elongation of rice mesocotyl and coleoptile can facilitate the rapid emergence of seedlings under deep mechanized sowing. Currently, most of the cultivated rice accessions have short mesocotyls or coleoptiles, with only a few related genes cloned. However, understanding and enhancing the ability of rice seedlings to rapidly emerge from deep sowing depths is crucial. Herein, we assessed 745 core rice germplasm accessions sown under a soil cover depth of 10 cm and found few long mesocotyl and coleoptile germplasms. We conducted genome‐wide association study using six models to obtain three or more multi‐model co‐localization candidate regions and calculated Fst between the phenotypes of extreme samples to determine genetic differences. The candidate regions associated with mesocotyl and coleoptile lengths were identified by integrating Fst and multi‐model localization results. This multi‐model localization method may accelerate the mining of genes related to the mesocotyl and coleoptile, providing valuable targets for functional validation and marker‐assisted selection in rice breeding programs.
Differential growth, morphological characters, and yield of quinoa (Chenopodium quinoa Willd.) genotypes grown on salt degraded soil
Authors: Gul Mubbashir , Ikram Nabeel Ahmad , Abbas Tasawer , Iqbal Shahid , Hussain Abid , Mubeen Khurram , Ullah Sami , Farooq Naila 
Published: September 2024

AbstractQuinoa (Chenopodium quinoa Willd.), a high‐value halophytic crop, is a promising candidate to ensure food security in the scenario of increasing soil salinization due to climate change. In a 2‐year field study (during 2018–2019 and 2019–2020), 18 quinoa genotypes of different origins (Q‐4, Q‐6, Q‐9, Q‐7, Q11, Q‐15, Q‐22, Q‐24, Q‐27, Q‐45, Q‐50, Q‐51, Q‐52, Q‐76, Q‐81, Q82, Q‐124, and Q‐126) were grown at two different locations (salt‐affected and normal soil having electrical conductivity (EC) of 16.24 and 1.76 dS m−1, respectively). Morphological, physiological, and yield parameters were recorded to assess the impact of salinity on different genotypes of quinoa. All the tested genotypes performed better in normal soil (37% more yield) than salt‐affected soils. Under salt‐affected conditions, differential salt tolerance responses of quinoa genotypes were observed. Among tested genotypes, Q‐7 achieved the highest chlorophyll content index, biological mass (7905 kg ha−1), and seed yield (1916 kg ha−1) under salt‐affected conditions, it was followed by Q‐81. Salt stress caused up to 94% reduction of seed yield in the salt‐sensitive genotype (Q‐11), while the salt‐tolerant genotype (Q‐81) showed only 15% reduction in seed yield. Morphological characteristics of quinoa genotypes were differently influenced by salt stress. The salt‐tolerant accessions Q‐7 and Q‐81 exhibited similar morphological characteristics. Based on the findings of this study, salt‐tolerant quinoa genotypes can be successfully grown in salt‐degraded soils (with EC ≤ 16.24 dS m−1) in extreme winter seasons with arid climatic conditions.
Examining the link between CSR perceptions and employee advocacy through organizational justice: Can corporate hypocrisy mitigate?
Authors: Gupta Pragya , Singh Sonali , Broccardo Laura , Alzeiby Ebtesam Abdullah 
Published: September 2024

AbstractThis research aims to understand the relationship between employees' perceptions of corporate social responsibility and employee advocacy behavior through organizational justice. Furthermore, it explores the moderating effect of corporate hypocrisy in the relationship of organizational justice with employee advocacy behavior. Grounded in signaling and cognitive inconsistency theories, the proposed hypotheses were tested on data collected from 360 employees from the hospitality sector. The study followed a time‐lagged approach. In phase 1, the data were collected for demographic variables, corporate social responsibility perceptions, and corporate hypocrisy. In the second phase, data were collected for organizational justice and employee advocacy behavior, using separate survey links. Smart PLS 4.0 was applied to test the relationships proposed in the research model. The study found that employees who positively perceive firms' corporate social responsibility will engage in advocacy behavior. The results suggest a significant mediating effect of procedural justice in the relationship between corporate social responsibility and employee advocacy behavior. However, the mediating effect of distributive justice in this relationship could not be established. Further, the study found evidence that corporate hypocrisy moderates the indirect relationship between corporate social responsibility perceptions and advocacy behavior via procedural justice. Also, to the best of our knowledge, literature has no empirical evidence of the moderating effect of corporate hypocrisy in the indirect association between the perception of corporate social responsibility and employee advocacy behavior via organizational justice. It provides several important implications for advancing theoretical knowledge and practical insights for hospitality industry practitioners.
Of shepherds and sheep: Who sets the agenda for firms' attention to social issues?
Authors: Leonel Ronei , Lee Jae Hwan , Perrault Elise 
Published: September 2024

AbstractCorporate social responsibility has received much attention regarding how it can benefit firms and why firms voluntarily address social issues. However, little is known about the problems to which firms choose to pay attention and what influences these decisions. We combine the attention‐based view of the firm and media agenda‐setting theories to propose that firms address the most prominent social issues as determined by the media. We analyze the frequency of 64 social issues in the CSR reports of 258 firms from 2006 to 2016 for a total sample of 86,208 issue‐firm‐year observations. We find that the salience of the problems in traditional media influences the social issues firms address in their CSR reports, and over time, the agenda‐setting effect of traditional media on firms has increased, solidifying traditional media's role as curators of social issues.
Carbon Dioxide as a Sustainable Reagent in Circular Hydrometallurgy
Authors: Rivera Rodolfo Marin , Binnemans Koen 
Published: September 2024

AbstractThis review highlights the use of CO2 as a reagent in hydrometallurgy, with emphasis on the new concept of circular hydrometallurgy. It is shown how waste CO2 can be utilised in hydrometallurgical operations for pH control or regeneration of acids for leaching. Metal‐rich raffinate solutions generated after removal of the valuable metals can serve as feedstocks for mineral carbonation, providing alternative avenues for CO2 sequestration. Furthermore, CO2 can also be used as a renewable feedstock for the production of chemical reagents that can find applications in hydrometallurgy as lixiviant, as precipitation reagent or for pH control. Mineral carbonation can be combined with chemical reactions involving metal complexation reagents, as well as with solvent extraction processes for the concurrent precipitation of metal carbonates and acid regeneration. An outlook for future research in the area is also presented.
Synthesis of Benzoic Acids from Electrochemically Reduced CO2 Using Heterogeneous Catalysts
Authors: Phan Ha , Gueret Robin , Martínez‐Pardo Pablo , Valiente Alejandro , Jaworski Aleksander , Slabon Adam , Martín‐Matute Belén 
Published: September 2024

AbstractA method for the synthesis of benzoic acids from aryl iodides using two of the most abundant and sustainable feedstocks, carbon dioxide (CO2) and water, is disclosed. Central to this method is an effective and selective electrochemical reduction of CO2 (eCO2RR) to CO, which mitigates unwanted dehalogenation reactions occurring when H2 is produced via the hydrogen evolution reaction (HER). In a 3‐compartment set‐up, CO2 was reduced to CO electrochemically by using a surface‐modified silver electrode in aqueous electrolyte. The ex‐situ generated CO further underwent hydroxycarbonylation of aryl iodides by MOF‐supported palladium catalyst in excellent yields at room temperature. The method avoids the direct handling of hazardous CO gas and gives a wide range of benzoic acid derivatives. Both components of the tandem system can be recycled for several consecutive runs while keeping a high catalytic activity.
Prognostic impact of being underweight in patients undergoing mitral TEER: The OCEAN‐Mitral registry
Authors: Higuchi Ryosuke , Izumo Masaki , Izumi Yuki , Saji Mike , Isobe Mitsuaki , Akashi Yoshihiro , Yamamoto Masanori , Asami Masahiko , Enta Yusuke , Nakashima Masaki , Shirai Shinichi , Mizuno Shingo , Watanabe Yusuke , Amaki Makoto , Kodama Kazuhisa , Yamaguchi Junichi , Naganuma Toru , Bota Hiroki , Ohno Yohei , Yamawaki Masahiro , Ueno Hiroshi , Mizutani Kazuki , Kubo Shunsuke , Otsuka Toshiaki , Hayashida Kentaro ,   the OCEAN‐Mitral Investigators
Published: September 2024

AbstractAimsMitral transcatheter edge‐to‐edge repair (M‐TEER) is a valid treatment option for severe mitral regurgitation (MR), necessitating accurate risk stratification of M‐TEER candidates for effective patient selection, optimal periprocedural care and improved long‐term outcomes. The body mass index (BMI) is a simple and practical prognostic index, and the obesity paradox has been widely reported.Methods and ResultsBetween April 2018 and June 2021, 2149 patients undergoing M‐TEER were registered in the prospective multicentre registry and classified into three groups: underweight (BMI < 18.5 kg/m2), normal weight (18.5 ≤ BMI < 25 kg/m2) and overweight and obese (25 kg/m2 ≦ BMI) [Correction added on 17 October 2024, after first online publication: In the preceding sentence, “18.5 ☆ BMI < 25 kg/m2” and “25 kg/m2 ☆ BMI” have been corrected to “18.5 ≤ BMI < 25 kg/m2” and “25 kg/m2 ≦ BMI” in this version.] The impact of underweight on the all‐cause, cardiovascular and non‐cardiovascular mortality following M‐TEER was evaluated [follow‐up duration: 436 (363–733) days]. The participants (median BMI: 21.1 kg/m2) were categorized as underweight (n = 450, 20.9%), normal weight (n = 1409, 65.6%) and overweight and obese (n = 290, 13.5%). Compared with the other two groups, the underweight group exhibited several negative prognostic factors, including older age, frailty, no dyslipidaemia, hypoalbuminaemia, residual MR and non‐home discharge. Underweight patients had the highest rate of all‐cause, cardiovascular and non‐cardiovascular mortality, whereas those in the other two groups were similar. As per the multivariate analysis, underweight itself was associated with all‐cause mortality (hazard ratio: 1.52, 95% confidence interval: 1.17–1.97, P = 0.009) and cardiovascular mortality (hazard ratio: 1.45, 95% confidence interval: 1.04–2.01, P = 0.028).ConclusionsUnderweight patients had the highest mortality rate after M‐TEER. Comorbidities, residual MR, discharge disposition and underweight status were correlated with postprocedural outcome.
An Efficient Analytical Method for Determining Transition Temperatures in Core‐Shell Spin Crossover Nanoparticles Described by an Extended Ising‐Like Model
Authors: El Islam Belmouri Nour , Cazelles Catherine , Linares Jorge , Boukheddaden Kamel 
Published: September 2024

AbstractThis contribution is dedicated to the analysis of the size and interaction parameters effects on the thermal properties of square‐shaped cross‐spin transition core‐shell nanoparticles. The present study is carried out by varying the shell size at fixed core size and vice versa. In this problem, the core and shell are active from the spin transition point of view, while having different properties in terms of ligand field (transition temperatures) and interactions. The resulting nanoparticle is described by an Ising‐type model including the three interaction parameters JCC, JSS and JCS coupling core‐core, shell‐shell and core‐shell sites, respectively. The thermodynamic investigations have been carried out in 3 different ways: (i) by Monte Carlo Entropic Sampling (MCES) for small size nanoparticles (
) (ii) by usual Monte Carlo Metropolis for higher dimensions (iii) by an analytical method deducing the equilibrium temperature of the system from the various local environments. We demonstrate that, as long as a clear plateau region occurs in the thermal‐dependence of the high‐spin fraction, an excellent agreement is obtained, allowing to predict analytically the evolution of the transition temperatures. The limitations of the method are discussed in the case of strong interference between the thermal dependences of the core and shell.