bluuebunny/crossref_metadata_2025_split huggingface dataset:
EU and Russia Co-Optation: (Re-)shaping the Ideas and Beliefs in the Moldovan and Armenian Societies
Authors: Burmester Isabell 
Published: February 2025

Abstract
This chapter explores the co-optation strategies employed by the EU and Russia in Moldova and Armenia, focusing on how these powers sought to shape the ideas and beliefs within these societies. Russia’s co-optation efforts leveraged its cultural advantage rooted in Soviet-era ties, promoting a common language, media, and religious connections. In contrast, the EU aimed to co-opt Moldovan and Armenian societies through the promotion of democratisation and liberal values, primarily targeting Civil Society Organisations (CSOs) and cultural diversity initiatives. The chapter examines how these differing strategies were received by various segments of Moldovan and Armenian societies. CSOs generally viewed the EU’s democracy promotion positively and attempted to diffuse European values within their broader societies. However, the general public in both countries often found Russian traditional values more relatable and remained cautious of “Western” liberal values. The chapter highlights the complex interplay of historical ties, cultural influences, and strategic communication in the co-optation process, revealing how the EU and Russia’s efforts were perceived differently across societal sectors in Moldova and Armenia.
Conclusion and Way Forward: What Future for the Region and How We Study It?
Authors: Burmester Isabell 
Published: February 2025

Abstract
This book critically examined the dichotomy in the literature regarding the differing influences of the EU and Russia in their shared neighbourhood. Through the development of a conceptual framework encompassing three ideal-typical mechanisms of hegemonic power (coercion, prescription, and co-optation) the study systematically compared EU and Russian neighbourhood policies in Eastern Europe and the South Caucasus. Empirical analysis of four cases (EU-Moldova, EU-Armenia, Russia-Moldova, and Russia-Armenia) highlighted the nuanced ways each power exerted influence, revealing both differences and similarities in their approaches. The study found that both the EU and Russia employed all three mechanisms, but with varying methods and effectiveness. Coercion by Russia was more unilateral and punitive, whereas the EU institutionalised its coercive measures within negotiated frameworks. In terms of prescription, the EU’s regulatory clarity contrasted with the complexity and incoherence of Russian standards within the EAEU. Co-optation efforts also differed, with Russia leveraging shared language, culture, and religion, while the EU focused on promoting European values. The analysis revealed that the legitimacy of these actions played a crucial role, with the EU generally perceived more positively than Russia, whose actions were often viewed as unpredictable and punitive. The findings also demonstrated a convergence in the hegemonic practices of the EU and Russia over time, especially post-2015, as both powers intensified their influence strategies. The study calls for future research to explore the interactive dynamics between regional hegemons and to examine how perceptions and local contexts shape power relations. It suggests extending the framework to other regions, such as Central Asia, South Asia, and Latin America, to understand the dynamics of regional hegemony in different geopolitical contexts. The insights from this research contribute to a deeper understanding of the complex interplay of hegemonic power in international relations, emphasising the importance of perceptions, legitimacy, and local contexts in shaping power dynamics.
Resource Allocation for Trustworthy Artificial Intelligence Projects in African Context
Authors: Azeez Abiola Joseph , Tiokou Elnathan , Ugar Edmund Terem 
Published: February 2025

Abstract
This study pursues one question: What are the implications of funding disparities on the development and implementation of trustworthy AI frameworks tailored to the African context, and how can proactive strategies be employed to address these disparities towards developing the African trustworthy AI projects landscape? In response, this chapter addresses resource allocation challenges in creating a trustworthy AI framework within the African context. It highlights concerns about Western-biased AI technologies and the historical impact of colonialism on funding inadequacies, which perpetuate technological colonialism. The argument stresses the need for proactive strategies from African governments to foster AI development. Despite the projected $15.7 trillion global economic value of AI by 2030, Africa's share remains disproportionately low. For instance, in 2022, the US invested $47.7 billion in AI, while Africa's investment was only $2.0 billion. Moreover, Africa's AI investments often come from Western sources, which further exacerbates funding biases. The chapter aims to demonstrate how this funding gap hampers the development of trustworthy AI from an African perspective. Drawing on global AI projects, it advocates for addressing the funding deficit to prioritise trustworthy AI research in Africa. Furthermore, the chapter proposes an ideal trustworthy AI model aligned with African ontology, emphasising relationality and human-centeredness. Lastly, it offers insights on channelling financial resources effectively, including dormant fund utilisation, corporate social responsibility, partnerships, and community-driven initiatives, to foster a trustworthy AI framework rooted in the African ethos.
Soziale Innovationen und die sozial-ökologische Transformation urbaner Mobilität
Authors: Lanzendorf Martin , Baumgartner Annabell , Klinner Nora 
Published: February 2025

Zusammenfassung
In diesem Beitrag untersuchen wir die Rolle sozialer Innovationen für die sozial-ökologische Transformation urbaner Mobilität. Wir verstehen darunter Veränderungen, die auf die Entwicklung neuer Alltagspraktiken und Organisationsmodelle abzielen, um Lösungen für gesellschaftliche Herausforderungen zu finden. Konkret untersuchen wir drei verkehrspolitische Maßnahmen, die zur Herausbildung und Stabilisierung neuer, weniger automobilorientierter Alltagspraktiken beitragen: (i) die Umgestaltung des öffentlichen Raums durch eine veränderte Nutzung und ggf. Verteuerung bisher für das Parken von Pkw genutzter Flächen, (ii) die Umwandlung von Pkw-Spuren auf Hauptverkehrsstraßen zu Fahrradspuren sowie (iii) die Schließung einer innerstädtischen Hauptverkehrsstraße für den Pkw-Verkehr. Insgesamt wird deutlich, dass die Zustimmung der Bevölkerung zu den genannten Maßnahmen – trotz öffentlichkeitswirksamer Proteste und Kampagnen dagegen – überraschend hoch ist. Dabei werden sowohl Unterschiede je nach Wohnviertel als auch je nach Mobilitätspraktiken und der individuellen Bereitschaft, die eigene Autonutzung zu reduzieren, erkennbar. Vielversprechend scheinen zukünftig von Wissenschaft und Praxis angestoßene partizipative Prozesse in urbanen Quartieren, um die Mobilitätswende weiter voran zu bringen.
Swiss Education System, Teacher Training and Teacher Shortage
Authors: Keller-Schneider Manuela , Schneider Boye Salome 
Published: February 2025

Abstract
Switzerland, as well as many other countries, is facing a teacher shortage. Due to the increasing number of students and the retirement of the baby-boomer-generation of teachers, there is a lack of teachers. The recruitment of teachers is challenging politics, Universities of Teacher Education and school administrations. This article focuses on the situation in Switzerland, contextualizing the situation within explanations on the education system and on teacher education.
Switzerland offers eleven years of compulsory schooling; private schooling is very rare (less than 5%). Teacher education is offered at Universities of Teacher Education. Pre-primary and primary teachers (classes minus 2 to 6) are qualified with a Bachelor’s degree, lower secondary teachers (7–9) with a Masters’. After graduating beginning teachers seek an employment and secure a contract with school administration, with the possibility of terminating the contract mutually. As part of an induction program, beginning teachers can access counselling and further education. Universities of Teacher Education and mentors in local schools run this program.
Teacher shortage is a cyclic phenomenon, the current teacher shortage is mainly caused by demographic factors, such as increasing number of students, entering school on different levels, and the numerous retirements of teachers of the baby-boomer generation. While other contributing factors are explored, no significant determinants have been identified. The results demonstrate that the teaching profession remains an attractive career decision. To attract more students to teacher education, alternative teacher education programs are developed, aiming especially at second career teacher students. However, the shortage continuous to grow, and the lack of qualified teachers remains substantial. To mitigate the shortage, people without teacher education can get a teaching job as well, albeit limited to a one-year contract. After an accounted successful first year as an unqualified teacher and a successfully passed assessment, they can enroll at the University of Teacher Education and study to become a teacher. The article highlights different aspects of the Swiss school system, teacher education and the teaching profession as well as an insight on teacher shortage situation in Switzerland and the efforts taken.
Literarische Interventionen in polarisierte Öffentlichkeiten bei Claudia Rankine und Carrie Mae Weems
Authors: Bosch Aida , Kley Antje 
Published: February 2025

Zusammenfassung
Dieser Beitrag geht der Frage nach, wie künstlerische Innovationen eine kritische Intervention in polarisierte Öffentlichkeiten ermöglichen. In zwei Fallstudien werden ästhetisch innovative, intermediale Text-Bild-Kollagen der Lyrikerin Claudia Rankine und der Fotografin Carrie Mae Weems untersucht. Durch Formate mit aufschlussreichen Wechselwirkungen zwischen Texten und Bildern zeigen die Arbeiten der beiden afroamerikanischen Künstlerinnen Alltagserfahrungen von Differenz und Solidarität in gewachsenen historischen Strukturen mit rassistischer Prägung. Wir untersuchen, mit welchen ästhetischen Strategien Rankines und Weems’ Text-Bild-Kollagen in häufig polemisch geführte öffentliche Diskurse der Gegenwart intervenieren. Dabei werden dichte Beschreibungen des Verhältnisses zwischen ästhetischen Formen, politischen Positionierungen und öffentlichen Verhandlungen entwickelt. Mit ihrer symbolischen Kraft arbeiten Rankines und Weems’ Werke gegen öffentlich eingefahrene Rezeptionsprozesse; sie stellen neue Bilder und Begriffe gegen rassistisch geprägte Muster im öffentlichen Austausch, die gleichermaßen in ihrer Ästhetik wie auch in ihrer gesellschaftlichen Gestaltungskraft wahrgenommen werden wollen. Sie bringen die selbstverständliche Forderung mit sich, an den privilegierten Orten des sozialen Raums Platz zu finden. Die hier untersuchten Arbeiten entfalten über ihre Ästhetik Kritik an historisch verfestigten Strukturen der Öffentlichkeit und entwickeln darüber hinaus zuversichtliche und potentiell wirkmächtige Entwürfe für neue Weisen des Zusammenlebens.
An Effective Data Replication Strategy and the Improvement of the Storage Environment
Authors: Ramesh Cheripelli , Srinivasulu Bijjam , Suresh Babu M. , Keerthi M. , Indira Priyadarshini G. , Grace Verghese Marlene 
Published: February 2025

Abstract
Data replication is one of many data protection methods that help data centers prevent business disruptions. It copies stored data to a remote or local system. It enhances redundancy if the main storage backup system fails. It reduces system failure downtime and facilitates natural disasters and human mistake recovery. This paper discusses how to establish advanced file remote replication and store the same dataset on different computers for data protection and content dissemination. Customers can restore data access in DR arrays in case of primary production storage array failure. A user-friendly interface lets Unushered management console users manage data. Advanced replication solutions optimize a single file resource to replicate to multiple target systems to improve data security, disaster recovery, and availability. Advanced replication technologies are better for enterprises with critical data needs, high data availability, and complex IT infrastructures because they are more robust and feature rich. These technologies assist current data management techniques to protect data and preserve business continuity during disruptions or disasters. This research will assist unity storage administrators in configure and troubleshooting Advanced File Replication.
Lie Affgebras Vis-à-Vis Lie Algebras
Authors: Andruszkiewicz Ryszard R. , Brzeziński Tomasz , Radziszewski Krzysztof 
Published: February 2025

Abstract
It is shown that any Lie affgebra, that is an algebraic system consisting of an affine space together with a bi-affine multiplication satisfying affine versions of the antisymmetry and Jacobi identity, is isomorphic to a Lie algebra together with an element and a specific generalized derivation (in the sense of Leger and Luks in J Algebra 228:165–203, 2000). These Lie algebraic data can be taken for the construction of a Lie affgebra or, conversely, they can be uniquely derived for any Lie algebra fibre of the Lie affgebra. The close relationship between Lie affgebras and (enriched by the additional data) Lie algebras can be employed to attempt a classification of the former by the latter. In particular, up to isomorphism, a complex Lie affgebra with a simple Lie algebra fibre

$$\mathfrak {g}$$

g

is fully determined by a scalar and an element of

$$\mathfrak {g}$$

g

fixed up to an automorphism of

$$\mathfrak {g}$$

g

, and it can be universally embedded in a trivial extension of

$$\mathfrak {g}$$

g

by a derivation. The study is illustrated by a number of examples that include all Lie affgebras with one-dimensional, non-abelian two-dimensional,

$$\mathfrak {s}\mathfrak {l}(2,\mathbb {C})$$

s
l
(
2
,
C
)

and

$$\mathfrak {s}\mathfrak {o}(3)$$

s
o
(
3
)

Lie algebra fibres. Extensions of Lie affgebras by cocycles and their relation to cocycle extensions of tangent Lie algebras is briefly discussed and illustrated by Lie affgebras with the Witt and Virasoro algebra fibres.
Investigation of the sensitivity of human A549 cells to paclitaxel and sesquiterpene lactone alantolactone via apoptosis induction
Authors: Bayar Irem , Erzurumlu Yalcin , Akkoc Senem , Bulut Zafer , Nizamlioglu Mehmet 
Published: February 2025

Abstract
Alantolactone (ALA), a sesquiterpene lactone compound obtained from Inula helenium root, is known to have anticancer activity in many types of cancer. Paclitaxel (PAX) is an effective first-line chemotherapeutic drug and is widely used in the treatment of lung cancer. The in vitro anticancer efficacy of combined treatment of ALA with PAX was investigated in the A549 human lung cancer cell line. The results show that ALA potentiated the effect of PAX-induced growth restriction and apoptosis in A549 cells. The combined administration more effectively decreased the Bcl-2 expression and increased Bax gene expression in cells compared to ALA or PAX alone. Also, co-treatment of ALA and PAX caused apoptotic nuclear formations. Additionally, coadministration increased the caspase-3 and caspase-9 levels more than PAX or ALA alone. The increase in NF-κB gene expression levels suggests that an NF-κB-independent apoptotic trigger mechanism operates in cells. Together, the present in vitro findings suggest that ALA may contribute as a potential therapeutic strategy in the treatment of lung cancer.
Lupin flour as a wheat substitute in conventional and sourdough breadmaking: impact on bread physicochemical properties and volatile profile
Authors: Nigro Gianfilippo , Gasparre Nicola , Vurro Francesca , Pasqualone Antonella , Rosell Cristina M. 
Published: February 2025

Abstract
Enhancing the nutritional profile of baked goods while addressing sustainability challenges means finding different sources of functional, sensory and nutritional ingredients. The aim of this study was to evaluate native lupin flour versus spontaneously fermented lupin flour as ingredient for wheat breadmaking. For that purpose, wheat flour was supplemented with 15–30 g/100 g lupin flour (LF15, LF30) or freeze-dried lupin sourdough (LS15, LS30) and dough and breads were assessed in comparison with wheat bread (control). Both lupin flour and lupin sourdough decreased dough stability, delayed the fermentation and lowered the pH. The incorporation of lupin flour increased the hardness of the crumb, except for when adding sourdough (15 g/100 g) that increased the bread expansion and enriched the volatile profile of bread. The analysis of the volatile compounds confirmed that lupin flour conferred fatty, green odor due to octanal, and when in the form of sourdough brought sour, and almond notes from acetic acid and benzaldehyde, respectively. Overall, lupin addition is a strategy to produce bread aligned with current trends towards sustainable and plant-based diets, particularly in the form of spontaneous type IV whole lupin sourdough up to 15 g/100 g wheat replacement.
Enzyme cascades for nucleotide sugar regeneration in glycoconjugate synthesis
Authors: Elling Lothar 
Published: February 2025

Abstract
Leloir glycosyltransferases are instrumental in the synthesis of glycoconjugates. Nucleotide sugars as their donor substrates are still considered expensive making preparative enzymatic syntheses economically unattractive. The review highlights the development and advancements of in situ regeneration cycles that utilize nucleotides as byproducts from glycosyltransferase reactions to synthesize respective nucleotide sugars. This approach reduces costs and avoids inhibition of Leloir glycosyltransferases. Regeneration cycles for ten nucleotide sugars are explored emphasizing enzyme cascades from salvage pathways and nucleotide biosynthesis. Additionally, the review highlights advancements involving sucrose synthase for the in situ regeneration of nucleotide sugars from sucrose. Sucrose synthase as the first example of a reversible glycosyltransferase reaction paved the way to establish economic syntheses of glycosylated natural products. Important aspects like enzyme immobilization and protein fusion to optimize processes are discussed. Overall, the review underscores the significance of advanced in situ regeneration cycles for nucleotide sugars for cost-effective access to high-value glycoconjugates.

Key points
• Enzyme cascades for in situ regeneration of nucleotide sugars

• Effective cycles for large-scale synthesis of glycoconjugates

• Regeneration of nucleotide sugars from sucrose by sucrose synthase

Graphical abstract
Pimitespib in patients with advanced gastrointestinal stromal tumors in Japan: an expanded access program
Authors: Naito Yoichi , Iwagami Shiro , Doi Toshihiko , Takahashi Tsuyoshi , Kurokawa Yukinori 
Published: February 2025

Abstract

Background
Pimitespib, an oral heat shock protein 90 inhibitor, significantly prolonged progression-free survival in patients with advanced gastrointestinal stromal tumors (GIST) in CHAPTER-GIST-301 study. This expanded access program was conducted to evaluate the safety and efficacy of pimitespib in Japanese patients with advanced GIST.

Methods
This multicenter, open-label, single-arm study was conducted in patients (≥ 20 years) with histologically confirmed GIST who had been previously treated with imatinib, sunitinib and regorafenib and had an Eastern Cooperative Oncology Group performance status of 0–1. Patients received pimitespib 160 mg/day for five days, followed by a 2-day rest, in 21-day cycles.

Results
Between February and August 2022, 23 patients were enrolled (median age 59.0 years). Over a median pimitespib treatment duration of 81.0 days, adverse events occurred in 22 patients (95.7%). The most common adverse events were diarrhea (73.9%), nausea (39.1%) and increased blood creatinine (30.4%). Serious adverse events occurred in two patients (tumor hemorrhage and tumor pain); neither was related to pimitespib. One patient had grade 3 diarrhea that was considered treatment-related. Four patients (17.4%) had eye disorders, all of which were grade 1 and treatment-related. The median progression-free survival was 4.2 months (95% confidence interval [CI] 1.9–6.2), the overall response rate was 0% (95% CI 0–16.1) and the disease control rate was 66.7% (95% CI 43.0–85.4).

Conclusions
Pimitespib was well tolerated and effective in patients with advanced GIST in real-world practice in Japan. No new safety signals were identified.
Trial registration: jRCT2031210526 registered 1 February 2022.
Influence of infection control for COVID-19 on nutrition in relatively healthy Japanese HD patients: a retrospective observational study
Authors: Chiba Yuki , Takahashi Ryotaro , Makino Rui , Yoshida Mai , Okamoto Koji , Nagasawa Tasuku , Kato Ichiro , Ito Sadatoshi , Tanaka Tetsuhiro , Miyazaki Mariko 
Published: February 2025

Abstract

Background
Infection control for the novel coronavirus disease 2019 (COVID-19) has been linked to decreased physical activity and nutritional deterioration in the general population; however, the influence on hemodialysis (HD) patients is not well discussed.

Methods
This multicenter retrospective study utilized the Geriatric Nutritional Risk Index (GNRI), Survival Index, and Nutritional Risk Index for Japanese HD patients (NRI-JH) to assess nutritional status and body composition over five observation periods. The primary endpoint was the body fluid removal rate (%) pre- and post-HD, whereas secondary endpoints included changes in GNRI, SI, body composition, and differences in NRI-JH.

Results
We enrolled 139 HD patients in three facilities. The results showed a decrease in GNRI score, which indicates nutritional deterioration, between February 2020 and August 2020 (96.8 (93.2–98.9) vs. 93.8 (90.8–97.6)) (P = 0.0005). Multivariable analysis revealed that nutritional deterioration was associated with higher C-reactive protein and lower hemoglobin levels (P = 0.0004 and P = 0.0010, respectively), which were more noticeable in the urban facility. Furthermore, nutritional deterioration was linked to a decrease in soft lean and somatic cell mass and an increase in body fat mass, suggesting reduced physical activity.

Conclusions
Nutritional deterioration was observed shortly after the first COVID-19 outbreak, suggesting an association with decreased physical activity.