bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early childhood growth and cognitive outcomes: Findings from theMAL‐EDstudy
Authors: Scharf Rebecca J. , Rogawski Elizabeth T. , Murray‐Kolb Laura E. , Maphula Angelina , Svensen Erling , Tofail Fahmida , Rasheed Muneera , Abreu Claudia , Vasquez Angel Orbe , Shrestha Rita , Pendergast Laura , Mduma Estomih , Koshy Beena , Conaway Mark R. , Platts‐Mills James A. , Guerrant Richard L. , DeBoer Mark D. 
Published: February 2018

AbstractAlthough many studies around the world hope to measure or improve developmental progress in children to promote community flourishing and productivity, growth is sometimes used as a surrogate because cognitive skills are more difficult to measure. Our objective was to assess how childhood measures of anthropometry correlate with measures of child development in low‐income settings with high prevalence of poor nutrition and enteric disease, to inform studies considering growth outcomes in the absence of direct child developmental skill assessment. Children from the MAL‐ED study were followed from birth to 24 months of age in field sites in 8 low‐ and middle‐income countries across 3 continents. Monthly weight, length, and head circumference measurements were performed. At 24 months, the Bayley Scales of Infant and Toddler Development was administered. We correlated cognitive measures at 24 months with anthropometric measurements from birth to 2 years comparing 3 constructs: absolute attained monthly measures, summative difference in measures from the mean growth curve, and rate of change in measures. Growth faltering at multiple time periods is related to Bayley cognitive outcomes at 24 months. Birthweight, overall growth by 18–24 months, and rate of growth in the 6‐ to 18‐month period were most associated with 24‐month developmental scores. In this study, head circumference measurements, compared with length, was more closely linked to cognitive scores at 24 months. Notably, all studies between growth and cognitive outcomes exhibited lowr2values (0.001–0.049). Anthropometric measures, particularly head circumference, were related to cognitive development, although explaining a low percent of variance. When feasible, direct measures of child development may be more useful.
Dissecting the virulence‐related functionality and cellular transcription mechanism of a conserved hypothetical protein in Xanthomonas oryzae pv. oryzae
Authors: Wang Bo , Wu Guichun , Zhang Yuqiang , Qian Guoliang , Liu Fengquan 
Published: February 2018

SummaryHypothetical proteins without defined functions are largely distributed in all sequenced bacterial genomes. Understanding their potent functionalities is a basic demand for bacteriologists. Xanthomonas oryzae pv. oryzae (Xoo), the causal agent of bacterial leaf blight of rice, is one of the model systems for the study of molecular plant pathology. One‐quarter of proteins in the genome of this bacterium are defined as hypothetical proteins, but their roles in Xoo pathogenicity are unknown. Here, we generated in‐frame deletions for six hypothetical proteins selected from strain PXO99A and found that one of them (PXO_03177) is required for the full virulence of this strain. PXO_03177 is conserved in Xanthomonas, and is predicted to contain two domains relating to polysaccharide synthesis. However, we found that mutation of this gene did not affect the production or modification of extracellular polysaccharides (EPSs) and lipopolysaccharides (LPSs), two major polysaccharides produced by Xoo relating to its infection. Interestingly, we found that inactivation of PXO_03177 significantly impaired biofilm formation and tolerance to sodium dodecyl sulfate (SDS), both of which are considered to play key roles during Xoo infection in rice leaves. These findings thus enable us to define a function for PXO_03177 in the virulence of Xoo. Furthermore, we also found that the global regulator Clp controls the transcription of PXO_03177 by direct binding to its promoter region, presenting the first cellular regulatory pathway for the modulation of expression of this hypothetical protein gene. Our results provide reference information for PXO_03177 homologues in Xanthomonas.
A population genetics analysis in clinical isolates of Sporothrix schenckii based on calmodulin and calcium/calmodulin‐dependent kinase partial gene sequences
Authors: Rangel‐Gamboa Lucia , Martinez‐Hernandez Fernando , Maravilla Pablo , Flisser Ana 
Published: February 2018

SummarySporotrichosis is a subcutaneous mycosis that is caused by diverse species of Sporothrix. High levels of genetic diversity in Sporothrix isolates have been reported, but few population genetics analyses have been documented. To analyse the genetic variability and population genetics relations of Sporothrix schenckii Mexican clinical isolates and to compare them with other reported isolates. We studied the partial sequences of calmodulin and calcium/calmodulin‐dependent kinase genes in 24 isolates; 22 from Mexico, one from Colombia, and one ATCC®6331™; the latter was used as a positive control. In total, 24 isolates were analysed. Phylogenetic, haplotype and population genetic analyses were performed with 24 sequences obtained by us and 345 sequences obtained from GenBank. The frequency of S. schenckii sensu stricto was 81% in the 22 Mexican isolates, while the remaining 19% were Sporothrix globosa. Mexican S. schenckii sensu stricto had high genetic diversity and was related to isolates from South America. In contrast, S. globosa showed one haplotype related to isolates from Asia, Brazil, Spain and the USA. In S. schenckii sensu stricto, S. brasiliensis and S. globosa, haplotype polymorphism (θ) values were higher than the nucleotide diversity data (π). In addition, Tajima's D plus Fu and Li's tests analyses displayed negative values, suggesting directional selection and arguing against the model of neutral evolution in these populations. In addition, analyses showed that calcium/calmodulin‐dependent kinase was a suitable genetic marker to discriminate between common Sporothrix species.
Does genotypic and species diversity of mycorrhizal plants and fungi affect ecosystem function?
Authors: Hazard Christina , Johnson David 
Published: February 2018

Contents

Summary
1122

I.
Introduction
1122

II.
Are there consistent patterns in diversity of mycorrhizal fungal genotypes and species across space?
1125

III.
What is the variation in functional traits and genes of mycorrhizal fungi at different taxonomic scales?
1125

IV.
How will environmental change impact the relationships between genotypic and species diversity of mycorrhizal fungi and ecosystem function?
1126

V.
Conclusions: considerations for future MEF research
1127

Acknowledgements
1127

References
1127

SummaryBoth genotypes and species of mycorrhizal fungi exhibit considerable variation in traits, and this variation can result in their diversity regulating ecosystem function. Yet, the nature of mycorrhizal fungal diversity–ecosystem function (MEF) relationships for both genotypes and species is currently poorly defined. New experiments should reflect the richness of genotypes and species in nature, but we still lack information about the extent to which fungal populations in particular are structured. Sampling designs should quantify the diversity of mycorrhizal fungal genotypes and species at three key broad spatial scales (root fragment, root system and interacting root systems) in order to inform manipulation experiments and to test how mycorrhizal fungal diversity both responds, and confers resilience to, environmental drivers.
Prevention and Treatment of Postoperative Pain after Lumbar Spine Procedures: A Systematic Review
Authors: Terracina Sergio , Robba Chiara , Prete Anna , Sergi Paola G. , Bilotta Federico 
Published: February 2018

AbstractBackground and ObjectiveIn the past 2 decades, in developed countries, spine procedures (surgical and percutaneous) had the highest absolute increase in case volume trend. The optimal approach to prevent and treat postoperative pain is continuously evolving. This systematic literature review presents evidence on safety and efficacy of pharmacological and nonpharmacological therapies to prevent and treat postoperative pain after lumbar spine procedures.Databases and Data TreatmentPublications listed in PUBMED and EMBASE were considered to identify randomized clinical trials suitable for inclusion in this systematic review. Key words for literature search were selected, with authors’ agreement, using the PICOS approach (participants, interventions, comparisons, outcomes, and study design).ResultsFifty‐nine randomized clinical trials (involving a total of 4,238 patients, with ages ranging from 18 to 86 years) published between January 2012 and September 2017 were retrieved. Data are presented according to the timing of therapy administration.Conclusion and RecommendationsClinical evidence on perioperative pain management in patients undergoing spine procedures have significantly evolved after the review published in 2012. The aim of this systematic review was to report the latest evidence published. These include the preoperative use of dexamethasone, which was shown to be able to reduce pain at mobilization but not to reduce pain at rest or total morphine consumption; the use of gabapentinoids as part of a multimodal analgesic approach; and the safety and effectiveness of the intraoperative use of ketamine, dexketoprofen, and tramadol. Finally, electrical nerve stimulation is gaining interest and is potentially suitable for clinical needs.
Impact of center volume and the adoption of laparoscopic donor nephrectomy on outcomes in pediatric kidney transplantation
Authors: Burg Jennifer M. , Scott David L. , Roayaie Kayvan , Maynard Erin , Barry John M. , Enestvedt C. Kristian 
Published: February 2018

AbstractReports for pediatric kidney transplant recipients suggested better outcomes for ODN compared to LDN. Contemporary outcomes stratified by donor type and center volume have not been evaluated in a national dataset. UNOS data (2000‐2014) were analyzed for pediatric living donor kidney transplant recipients. The primary outcome was GF; secondary outcomes were DGF, rejection, and patient survival. Live donor nephrectomies for pediatric recipients decreased 30% and transitioned from ODN to LDN. GF rates did not differ for ODN vs LDN (P = .24). GF was lowest at high volume centers (P < .01). Donor operative approach did not contribute to GF. LDN was associated with less rejection than ODN (OR 0.66, CI 0.5‐0.87, P < .01). Analysis of the 0‐ to 5‐yr recipient group showed no effect of ODN vs LDN on GF or rejection. For the contemporary era, there was no association between DGF and LDN in the 0‐ to 5‐yr group (OR 1.12, CI 0.67‐1.89, P = .67). Outcomes of kidney transplants in pediatric recipients following LDN have improved since its introduction and LDN should be the approach for live donor nephrectomy regardless of recipient age. The association between case volume and improved outcomes highlights future challenges in organ transplantation.
A New Kind of Nursing: Walking the labyrinth of Cook County Jail
Authors: Gorman Geraldine 
Published: February 2018

AbstractThis paper examines the application of public health nursing education with an emphasis on the social determinants of health within a correctional facility. The innate tension between public health practice and the punitive nature of correctional confinement is discussed through the perspective of student involvement. Exemplars of unexpected contingencies endemic to this practice setting are provided as are insights gleaned from this pilot collaboration between a college of nursing and a county correctional system.
Insights into intraspecific wood density variation and its relationship to growth, height and elevation in a treeline species
Authors: Fajardo A. 
Published: February 2018

AbstractThe wood economics spectrum provides a general framework for interspecific trait–trait coordination across wide environmental gradients. Whether global patterns are mirrored within species constitutes a poorly explored subject. In this study, I first determined whether wood density co‐varies together with elevation, tree growth and height at the within‐species level. Second, I determined the variation of wood density in different stem parts (trunk, branch and twigs).In situtrunk sapwood, trunk heartwood, branch and twig densities, in addition to stem growth rates and tree height were determined in adult trees ofNothofagus pumilioat four elevations in five locations spanning 18° of latitude. Mixed effects models were fitted to test relationships among variables.The variation in wood density reported in this study was narrow (ca. 0.4–0.6 g cm−3) relative to global density variation (ca. 0.3–1.0 g cm−3). There was no significant relationship between stem growth rates and wood density. Furthermore, the elevation gradient did not alter the wood density of any stem part. Trunk sapwood density was negatively related to tree height. Twig density was higher than branch and trunk densities. Trunk heartwood density was always significantly higher than sapwood density.Negative across‐species trends found in the growth–wood density relationship may not emerge as the aggregate of parallel intraspecific patterns. Actually, trees with contrasting growth rates show similar wood density values. Tree height, which is tightly related to elevation, showed a negative relationship with sapwood density.
Understanding Fear of Zika: Personal, Interpersonal, and Media Influences
Authors: Yang Chun , Dillard James Price , Li Ruobing 
Published: February 2018

AbstractFear of infectious disease often motivates people to protect themselves. But, it can also produce negative bio‐social‐psychological effects whose severity is on par with those of the disease. The WHO declaration of Zika as a world health crisis presented an opportunity to study factors that bring about fear. Beginning nine days after the WHO announcement, data were gathered from women aged 18–35 living in the southern United States (N= 719). Respondents reported experiencing fear of Zika at levels akin to those reported following other significant crises/disasters (e.g., the terrorist attacks of 9/11). Fear increased as a function of (1) personal, but not other‐relevance, (2) frequency of media exposure, but not media content, and (3) frequency of interpersonal exposure and interpersonal content. It is argued that media and interpersonal message sources may be innately predisposed to amplify, rather than attenuate, risk.
Eccentric exercise induces spatial changes in the mechanomyographic activity of the upper trapezius muscle
Authors: Madeleine P. , Hansen E. A. , Andersen R. E. , Kumorek M. , Mroczek D. , Samani A. , Kawczyński A. 
Published: February 2018

In this study, we hypothesized that the recordings of multichannel mechanomyography (MMG) of the upper trapezius muscle would reveal spatially dependent manifestations in the presence of delayed onset muscle soreness occurring 24 hours after eccentric exercise (ECC). Sixteen participants performed high‐intensity eccentric exercises (5 sets of 10 eccentric contractions at 100% of max elevation force) targeting the upper trapezius on their dominant side. Twelve accelerometers were attached to record MMG activity during submaximal exercise consisting of static and dynamic arm flexion and abduction. Measurements were taken before and 24 hours after ECC. Average rectified value (ARV), percentage of determinism (% DET), and recurrence (% REC) of the MMG signals were computed to estimate the level of muscular activity and the magnitude of regularity of the MMG. The ARV, % REC, and % DET maps revealed heterogeneous MMG activity of the upper trapezius 24 hours after ECC when compared with before. Increased ARV, % REC, and % DET were found 24 hours after ECC when compared with before. The study provides new key information on how a single muscle responds to ECC. Our findings suggest that multichannel MMG and nonlinear analyses may detect muscular and musculo‐tendinous alterations due to ECC.
Soil property differences among high‐ and average‐yielding soya bean areas in Arkansas, USA
Authors: Adams T. C. , Brye K. R. , Purcell L. C. , Ross W. J. , Gbur E. E. , Savin M. C. 
Published: February 2018

AbstractSoya bean [Glycine max (L.) Merr] yields >6719 kg/ha (100 bu/ac) have only recently and infrequently been achieved. Quantifying soil property differences between high‐ and average‐yielding areas can help to further identify non‐plant‐related properties contributing to soya bean yield potential. The objective of this study was to evaluate the effects of region and soil depth on soil property differences between high‐ and average‐yielding areas. In each of the seven regions of the ‘Grow for the Green’ yield contest in Arkansas, prior to or just after harvest in 2014 and 2015, soil samples were collected from the top 20 cm of one contest high‐yield (HY) area that was in close proximity to an average‐yield (AY) area. Across all regions and both years, soya bean yields differed (P < 0.05) between yield areas, averaging 4701 and 5498 kg/ha in AY and HY areas, respectively. Averaged across soil depth and years, numerous soil properties differed (P < 0.05) between HY and AY areas within at least one of seven regions. Total soil C content was at least 20.2% greater in the HY than in the AY area in three of seven regions. Extractable soil P content was, on average, 19.4 kg/ha greater in HY than in AY areas in three of the seven regions. Results from this study have the potential to help producers better understand soil properties that contribute to or hinder achieving ultra‐high (>6719 kg/ha) soya bean yields.
Management of injured patients who were Jehovah's Witnesses, where blood transfusion may not be an option: a retrospective review
Authors: Olaussen A. , Bade‐Boon J. , Fitzgerald M. C. , Mitra B. 
Published: February 2018

IntroductionManagement of major haemorrhage as a result of trauma is particularly challenging when blood is not an option (BNAO). Evidence on therapeutic strategies in this situation is limited. The aim of this study was to evaluate the management and outcomes of patients who identified themselves as Jehovah's Witnesses (who usually refuse blood products) with traumatic haemorrhage at an Australian major trauma centre.MethodsA retrospective review of patients from The Alfred Trauma Registry was conducted, including patients who were Jehovah's Witnesses presenting between January 2010 and January 2017. We examined demographics, injury characteristics, clinical progress, therapeutic interventions and outcomes at hospital discharge.ResultsThere were 34 patients meeting inclusion criteria, with 50% suffering major trauma. Anaemia was a clinical problem for 13 (38·2%) patients, with haemoglobin levels reaching a nadir of 69·7 g/l (95% CI: 56·7–82·7) on average 5·1 days (95% CI: 2·5–7·7) post admission. Various strategies were employed to reduce blood loss including six (46·2%) patients receiving tranexamic acid, nine (29·2%) patients receiving oral or intravenous iron and five (38·5%) receiving erythropoietin. Three patients received packed red cells, and two patients received synthetic haemoglobin‐based oxygen carriers.ConclusionsNumerous therapeutic strategies were employed inconsistently in this unique population of patients. Augmenting circulatory volume with an oxygen carrier acceptable to JW patients presents a novel approach to be considered in adjunct to other strategies. An international resource centre would assist clinicians faced with anaemia and BNAO.
Roots of Violence by ISIS, An Analysis on Beliefs
Authors: Bozorgmehri Majid 
Published: February 2018

ISIS was an Islamic fundamentalist organization which presents a radical version of Islamic beliefs, encourages holy violence, and considers others who do not agree with its understandings as apostates.As a theoretical debate, the discussions developed by Gregg could cover the arguments stated through this study. He considers Social Movements, Fundamentalists, and Cosmic Warriors as the frameworks of religious cruelty.Daesh`s Dogma could be analyzed in two levels: traditional platform and new generation literature. As the former, three pillars Salafism. Qutbism and Wahhabism shape the basements and frameworks of IS`s ideological structure. New generation literature, joined with an anti-western attitude and combined also with a Sense of revenge against the old powers of imperialism, justify the most violent acts everywhere.As an alternative of being shaped in traditional dogma, ISIS’s philosophy could be drawn from 3 new booklets. The Management of Savagery (Idarat al-tawahhush) written in 2000s by Abu Bakr al-Naji, is one of them.For methodological aspect, the content analysis, concentrated on the basic sources is selected and for discussing the arguments, a descriptive analytical method is opted.
An Experimental Investigation on Hysteresis in a Wet Gas Compressor
Authors: Bakken Martin , Bjørge Tor 
Published: February 2018

Performance monitoring of wet gas compressors is challenging due to the liquid phase impact on performance. Introduction of a liquid phase alters both the thermodynamics as well as the fluid dynamics of the compression process. Hence, understanding the flow interaction between the impeller, diffuser and volute is pivotal. Previous investigations have detected occurrence of compressor hysteresis at certain wet gas operating conditions, resulting in temporary deviations from the steady state compressor characteristics. This kind of behavior influences both the compressor stability and performance. Thus, being able to understand the onset of hysteresis and its impact on the compressor is paramount.
An experimental test campaign has been performed at the Norwegian University of Science and Technology (NTNU). The test facility is an open loop configuration consisting of a shrouded centrifugal impeller, a vaneless diffuser and a circular volute. The current investigation document the compressor performance shift and the occurrence of compressor hysteresis when gradually increasing the liquid load on a centrifugal compressor. Emphasis was put on the compressor performance and its correlation to the diffuser multiphase flow regime. The investigation revealed that there is a clear dependence between the diffuser multiphase flow characteristics and the compressor performance.