bluuebunny/crossref_metadata_2025_split huggingface dataset:
PLANETARY CANDIDATES OBSERVED BY KEPLER. VII. THE FIRST FULLY UNIFORM CATALOG BASED ON THE ENTIRE 48-MONTH DATA SET (Q1–Q17 DR24)
Authors: Coughlin Jeffrey L. , Mullally F. , Thompson Susan E. , Rowe Jason F. , Burke Christopher J. , Latham David W. , Batalha Natalie M. , Ofir Aviv , Quarles Billy L. , Henze Christopher E. , Wolfgang Angie , Caldwell Douglas A. , Bryson Stephen T. , Shporer Avi , Catanzarite Joseph , Akeson Rachel , Barclay Thomas , Borucki William J. , Boyajian Tabetha S. , Campbell Jennifer R. , Christiansen Jessie L. , Girouard Forrest R. , Haas Michael R. , Howell Steve B. , Huber Daniel , Jenkins Jon M. , Li Jie , Patil-Sabale Anima , Quintana Elisa V. , Ramirez Solange , Seader Shawn , Smith Jeffrey C. , Tenenbaum Peter , Twicken Joseph D. , Zamudio Khadeejah A. 
Published: May 2016

ABSTRACT
We present the seventh Kepler planet candidate (PC) catalog, which is the first catalog to be based on the entire, uniformly processed 48-month Kepler data set. This is the first fully automated catalog, employing robotic vetting procedures to uniformly evaluate every periodic signal detected by the Q1–Q17 Data Release 24 (DR24) Kepler pipeline. While we prioritize uniform vetting over the absolute correctness of individual objects, we find that our robotic vetting is overall comparable to, and in most cases superior to, the human vetting procedures employed by past catalogs. This catalog is the first to utilize artificial transit injection to evaluate the performance of our vetting procedures and to quantify potential biases, which are essential for accurate computation of planetary occurrence rates. With respect to the cumulative Kepler Object of Interest (KOI) catalog, we designate 1478 new KOIs, of which 402 are dispositioned as PCs. Also, 237 KOIs dispositioned as false positives (FPs) in previous Kepler catalogs have their disposition changed to PC and 118 PCs have their disposition changed to FPs. This brings the total number of known KOIs to 8826 and PCs to 4696. We compare the Q1–Q17 DR24 KOI catalog to previous KOI catalogs, as well as ancillary Kepler catalogs, finding good agreement between them. We highlight new PCs that are both potentially rocky and potentially in the habitable zone of their host stars, many of which orbit solar-type stars. This work represents significant progress in accurately determining the fraction of Earth-size planets in the habitable zone of Sun-like stars. The full catalog is publicly available at the NASA Exoplanet Archive.
A CHEMICAL KINETICS NETWORK FOR LIGHTNING AND LIFE IN PLANETARY ATMOSPHERES
Authors: Rimmer P. B. , Helling Ch 
Published: May 2016

ABSTRACT
There are many open questions about prebiotic chemistry in both planetary and exoplanetary environments. The increasing number of known exoplanets and other ultra-cool, substellar objects has propelled the desire to detect life and prebiotic chemistry outside the solar system. We present an ion–neutral chemical network constructed from scratch, Stand2015, that treats hydrogen, nitrogen, carbon, and oxygen chemistry accurately within a temperature range between 100 and 30,000 K. Formation pathways for glycine and other organic molecules are included. The network is complete up to H6C2N2O3. Stand2015 is successfully tested against atmospheric chemistry models for HD 209458b, Jupiter, and the present-day Earth using a simple one-dimensional photochemistry/diffusion code. Our results for the early Earth agree with those of Kasting for CO2, H2, CO, and O2, but do not agree for water and atomic oxygen. We use the network to simulate an experiment where varied chemical initial conditions are irradiated by UV light. The result from our simulation is that more glycine is produced when more ammonia and methane is present. Very little glycine is produced in the absence of any molecular nitrogen and oxygen. This suggests that the production of glycine is inhibited if a gas is too strongly reducing. Possible applications and limitations of the chemical kinetics network are also discussed.
Characterization of SIGIRR/IL-1R8 Homolog from Zebrafish Provides New Insights into Its Inhibitory Role in Hepatic Inflammation
Authors: Feng Wei , Gu Yi-Feng , Nie Li , Guo Dong-Yang , Xiang Li-xin , Shao Jian-zhong 
Published: May 2016

Abstract
Single Ig IL-1R–related molecule (SIGIRR, also called IL-1R8 or Toll/IL-1R [TIR]8), a negative regulator for Toll/IL-1R signaling, plays critical roles in innate immunity and various diseases in mammals. However, the occurrence of this molecule in ancient vertebrates and its function in liver homeostasis and disorders remain poorly understood. In this study, we identified a SIGIRR homology from zebrafish (Danio rerio [DrSIGIRR]) by using a number of conserved structural and functional hallmarks to its mammalian counterparts. DrSIGIRR was highly expressed in the liver. Ablation of DrSIGIRR by lentivirus-delivered small interfering RNA in the liver significantly enhanced hepatic inflammation in response to polyinosinic-polycytidylic acid [poly(I:C)] stimulation, as shown by the upregulation of inflammatory cytokines and increased histological disorders. In contrast, depletion of TIR domain–containing adaptor inducing IFN-β (TRIF) or administration of TRIF signaling inhibitor extremely abrogated the poly(I:C)-induced hepatic inflammation. Aided by the zebrafish embryo model, overexpression of DrSIGIRR in vivo significantly inhibited the poly(I:C)- and TRIF-induced NF-κB activations; however, knockdown of DrSIGIRR promoted such activations. Furthermore, pull-down and Duolink in situ proximity ligation assay assays showed that DrSIGIRR can interact with the TRIF protein. Results suggest that DrSIGIRR plays an inhibitory role in TRIF-mediated inflammatory reactions by competitive recruitment of the TRIF adaptor protein from its TLR3/TLR22 receptor. To our knowledge, this study is the first to report a functional SIGIRR homolog that existed in a lower vertebrate. This molecule is essential to establish liver homeostasis under inflammatory stimuli. Overall, the results will enrich the current knowledge about SIGIRR-mediated immunity and disorders in the liver.
Institutions and Investment in the South and East Asia and Pacific Region: Evidence from Meta-Analysis
Authors: Yerrabati Sridevi , Hawkes Denise Donna 
Published: May 2016

AbstractThe ability of any country to attract inward FDI is considered to depend on the quality of the economic governance found within that state. This study seeks to explore the value of quality economic governance in attracting FDI in South and East Asia by meta-synthesising 771 estimates from 48 empirical studies published between 1980 and 2012. The authors find evidence that countries with good quality regulation and low levels of corruption are able to attract more FDI. They also find that countries with stronger legal systems are rewarded with higher levels of inward FDI. The results of the meta-regression suggest that investing in quality economic governance is rewarded in the global economy through high levels of inward FDI.
The Brain's Representational Power
Authors: Pennartz Cyriel M.A. 
Published: May 2016

A neuroscientifically informed theory arguing that the core of qualitative conscious experience arises from the integration of sensory and cognitive modalities.
Although science has made considerable progress in discovering the neural basis of cognitive processes, how consciousness arises remains elusive. In this book, Cyriel Pennartz analyzes which aspects of conscious experience can be peeled away to access its core: the “hardest” aspect, the relationship between brain processes and the subjective, qualitative nature of consciousness. Pennartz traces the problem back to its historical roots in the foundations of neuroscience and connects early ideas on sensory processing to contemporary computational neuroscience.
What can we learn from neural network models, and where do they fall short in bridging the gap between neural processes and conscious experience? Do neural models of cognition resemble inanimate systems, and how can this help us define requirements for conscious processing in the brain? These questions underlie Pennartz's examination of the brain's anatomy and neurophysiology. The perspective of his account is not limited to visual perception but broadened to include other sensory modalities and their integration. Formulating a representational theory of the neural basis of consciousness, Pennartz outlines properties that complex structures must express to process information consciously. This theoretical framework is constructed using empirical findings from neuropsychology and neuroscience as well as such theoretical arguments as the Cuneiform Room and the Wall Street Banker. Positing that qualitative experience is a multimodal and multilevel phenomenon at its very roots, Pennartz places this body of theory in the wider context of mind-brain philosophy, examining implications for our thinking about animal and robot consciousness.
Ten Tips for Maximizing the Effectiveness of Emergency Medicine Procedure Laboratories
Authors: Hughes Patrick G. , Crespo Maria , Maier Tina , Whitman Alia , Ahmed Rami 
Published: May 2016

Abstract
Incorporating simulation-based medical education techniques is paramount to ongoing training of emergency physicians. Effective procedure laboratories give learners hands-on experience in life-saving procedures they may otherwise not have clinical exposure to and also prevent skill decay. Using procedural education, adult learning theory, deliberate practice, and mastery learning strategies, the authors offer 10 tips to educators for designing an effective emergency medicine procedure laboratory.
Nanohole and dot patterning processes on quartz substrate by R–θ electron beam lithography and nanoimprinting
Authors: Watanabe Tsuyoshi , Taniguchi Kazutake , Suzuki Kouta , Iyama Hiromasa , Kishimoto Shuji , Sato Takashi , Kobayashi Hideo 
Published: May 2016

Abstract
Fine hole and dot patterns with bit pitches (bp’s) of less than 40 nm were fabricated in the circular band area of a quartz substrate by R–θ electron beam lithography (EBL), reactive ion etching (RIE), and nanoimprinting. These patterning processes were studied to obtain minimum pitch sizes of hole and dot patterns without pattern collapse. The patterning on the circular band was aimed to apply these patterning processes to future high-density bit-patterned media (BPM) for hard disk drive (HDD) and permanent memory for the long life archiving of digital data. In hole patterning, a minimum-22-nm-bp and 8.2-nm-diameter pattern (1.3 Tbit/in.2) was obtained on a quartz substrate by optimizing the R–θ EBL and RIE processes. Dot patterns were replicated on another quartz substrate by nanoimprinting using a hole-patterned quartz substrate as a master mold followed by RIE. In dot patterning, a minimum-30-nm-bp and 18.5-nm-diameter pattern (0.7 Tbit/in.2) was obtained by introducing new descum conditions. It was observed that the minimum bp of successful patterning increased as the fabrication process proceeded, i.e., from 20 nm bp in the first EBL process to 30 nm bp in the last quartz dot patterning process. From the measured diameters of the patterns, it was revealed that pattern collapse was apt to occur when the value of average diameter plus 3 sigma of diameter was close to the bp. It was suggested that multiple fabrication processes caused the degradation of pattern quality; therefore, hole patterning is more suitable than dot patterning for future applications owing to the lower quality degradation by its simple fabrication process.
Design of piezoelectric MEMS cantilever for low-frequency vibration energy harvester
Authors: Takei Ryohei , Makimoto Natsumi , Okada Hironao , Itoh Toshihiro , Kobayashi Takeshi 
Published: May 2016

Abstract
We report the design of piezoelectric MEMS cantilevers formed on a silicon-on-insulator wafer to efficiently harvest electrical power from harmonic vibration with a frequency of approximately 30 Hz. Numerical simulation indicates that a >4-µm-thick top silicon layer and >3-µm-thick piezoelectric film are preferable to maximize the output electrical power. An in-plane structure of the cantilever is also designed retaining the footprint of the cantilever. The simulation results indicate that the output power is maximized when the length ratio of the proof mass to the cantilever beam is 1.5. To ensure the accuracy of the simulation, we fabricated and characterized cantilevers with a 10-µm-thick top silicon layer and a 1.8-µm-thick piezoelectric film, resulting in 0.21 µW at a vibration of 0.5 m/s2 and 25.1 Hz. The measured output power is in agreement with the simulated value, meaning that the design is significantly reliable for low-frequency vibration energy harvesters.
Information transfer using wearable thin electrotactile displays with microneedle electrodes
Authors: Tezuka Mayuko , Kitamura Norihide , Miki Norihisa 
Published: May 2016

Abstract
Tactile sensation is considered as a promising information transfer tool that can replace or compensate for sight and hearing information. In this study, we developed a sheet-type electrotactile display with microneedle electrodes. This flexible and thin display is suitable for wearable applications. It can present tactile sensation to the skin at a low voltage by penetrating the stratum corneum with microneedles. As a proof-of-concept experiment of transferring information via tactile sensation, we first tried to convey signals of two patterns using a single display. Next, we attempted to use multiple displays and experimentally investigated the spatial resolution of the tactile sensation on the forearm. Finally, 3-bit information was successfully transferred by three devices attached to the forearm.
Influence of bonding pressure on thermal resistance in reactively-bonded solder joints
Authors: Kanetsuki Shunsuke , Miyake Shugo , Kuwahara Koichi , Namazu Takahiro 
Published: May 2016

Abstract
To realize the practical use of reactively bonded solder joints for thermally sensitive devices such as MEMS and electrical modules, we quantitatively measure the thermal resistance of solder joints fabricated by Al/Ni self-propagating exothermic reaction. By the laser flash method with response function analysis, the influence of bonding pressure on the thermal resistance of the reactive joints is investigated. The thermal resistance of the joints obtained by 3 MPa bonding is higher than that by 20 MPa bonding. By cross-sectional scanning electron microscopy (SEM) observation, many voids are found in the vicinity of the interface between the reacted AlNi and bottom-side solder layers in 3 MPa joints. In 20 MPa joints, a Ni-rich AlNi intermetallic compound instead of voids is produced around the interface. For reducing the thermal resistance of the reactive joints, the void generation mechanism is discussed in light of SEM observation and electron probe microanalysis (EPMA) analysis results.
Synthesis of no‐glycerol biodiesel through transesterification catalyzed by CaO from different precursors
Authors: Tang Ying , Yan Tianlan , Shen Bo , Li Huafeng , Jeje Ayodeji 
Published: May 2016

AbstractThree component mixtures of canola oil, dimethyl carbonate, and methanol, catalyzed by suspended calcium oxide (CaO) particles, produced a biodiesel that required little further processing. Only the catalyst particles needed to be recovered and reused. Substrates for the CaO were laboratory‐grade acetate, hydroxide, oxalate, and carbonate compounds of calcium heated to temperatures ≥ 850 °C at which calcination is complete. The catalyst substrate and conversion process determined the effectiveness of the catalyst for high product yields. CaO derived from calcium carbonate exhibited morphological characteristics that included larger contact surface areas, and thus more reactive sites, compared to the other precursors. Moreover, with only 0.17 μg/g (0.017 %) free glycerol present in the produced biodiesel, the biodiesel can be used directly without further treatment.
Multimodal analysis of cortical chemoarchitecture and macroscale fMRI resting‐state functional connectivity
Authors: van den Heuvel Martijn P. , Scholtens Lianne H. , Turk Elise , Mantini Dante , Vanduffel Wim , Feldman Barrett Lisa 
Published: May 2016

AbstractThe cerebral cortex is well known to display a large variation in excitatory and inhibitory chemoarchitecture, but the effect of this variation on global scale functional neural communication and synchronization patterns remains less well understood. Here, we provide evidence of the chemoarchitecture of cortical regions to be associated with large‐scale region‐to‐region resting‐state functional connectivity. We assessed the excitatory versus inhibitory chemoarchitecture of cortical areas as anExInratio between receptor density mappings of excitatory (AMPA, M1) and inhibitory (GABAA, M2) receptors, computed on the basis of data collated from pioneering studies of autoradiography mappings as present in literature of the human (2 datasets) and macaque (1 dataset) cortex. Cortical variation inExInratio significantly correlated with total level of functional connectivity as derived from resting‐state functional connectivity recordings of cortical areas across all three datasets (human I:P = 0.0004; human II:P = 0.0008; macaque:P = 0.0007), suggesting cortical areas with an overall more excitatory character to show higher levels of intrinsic functional connectivity during resting‐state. Our findings are indicative of the microscale chemoarchitecture of cortical regions to be related to resting‐state fMRI connectivity patterns at the global system's level of connectome organization.Hum Brain Mapp 37:3103–3113, 2016. ©2016 Wiley Periodicals, Inc.
Intracellular MMP3 Promotes HSP Gene Expression in Collaboration With Chromobox Proteins
Authors: Eguchi Takanori , Calderwood Stuart K. , Takigawa Masaharu , Kubota Satoshi , Kozaki Ken‐ichi 
Published: May 2016

ABSTRACTMatrix metalloproteinases (MMPs) are crucial factors in tumor progression, inflammatory/immune responses and tissue development/regeneration. Of note, it has been known that MMPs promote genome instability, epithelial‐mesenchymal transition, invasion, and metastasis in tumor progression. We previously reported that human MMP3 could translocate into cellular nuclei and control transcription in human chondrosarcoma‐derived cells and in articular cartilage (Eguchi et al. [2008] Mol Cell Biol 28(7):2391–2413); however, further transcriptional target genes and cofactors of intranuclear MMP3 have not been uncovered. In this paper, we used transcriptomics analysis in order to examine novel transcriptional target genes regulated by intracellular MMP3. We found that mRNA levels of HSP family members (HSP70B′, HSP72, HSP40/DNAJ, and HSP20/CRYAB) are upregulated by the intracellular MMP3 overload. Bioinformatic analysis predicted several transcription factors that possibly interact with MMP3. Among these factors, heat shock factor 1 (HSF1) cooperated with the MMP3 to activate the HSP70B′ gene promoter in reporter gene assays, while a dominant negative HSF1 blocked the role for MMP3 in the trans‐activation. The hemopexin‐like repeat (PEX) domain of the human MMP3 was essential for transcriptional induction of the HSP70B′ gene. In addition, chromobox proteins CBX5/HP1α and CBX3/HP1γ cooperated with the PEX domain in induction of HSP70B′ mRNA. Taken together, this study newly clarified that intracellular MMP3 cooperate with CBXs/HP1s in transcriptional promotion of HSP genes. J. Cell. Biochem. 118: 43–51, 2017. © 2016 Wiley Periodicals, Inc.
Does topical use of autologous serum help to reduce post-tonsillectomy morbidity? A prospective, controlled preliminary study
Authors: Kara M , Erdoğan H , Altinişik H B , Aylanç H , Güçlü O , Dereköy F S 
Published: May 2016

AbstractBackground:To evaluate the effects of autologous serum usage on throat pain, haemorrhage and tonsillar fossa epithelisation in patients after tonsillectomy.Methods:Thirty-two patients (aged 4–15 years) were included in the study. Tonsillectomy was performed and autologous serum was administered topically to the right tonsillar fossa during the operation, and at 8 and 24 hours post-operatively. The left side served as the control. A visual analogue scale was used to record the patient's pain every day. Each patient's oropharynx was observed on the 5th and 10th post-operative days to examine bleeding and epithelisation.Results:The pain scores for the side administered autologous serum were significantly lower than those for the control side, on the night following the operation and on the 1st, 2nd, 5th and 6th post-operative days. Tonsillar fossa epithelisation was significantly accelerated on the study side compared with the control side on the 5th and 10th post-operative days.Conclusion:In tonsillectomy patients, topically administered autologous serum contributed to throat pain relief and tonsillar fossa epithelisation during the post-operative period.
Habitat suitability models indicate the White-breasted ThrasherRamphocinclus brachyurusoccupies all suitable habitat in Saint Lucia
Authors: SASS EMMA M. , MORTENSEN JENNIFER L. , REED J. MICHAEL 
Published: May 2016

SummaryHabitat suitability models can guide species conservation by identifying correlates of occurrence and predicting where species are likely to occur. We created habitat suitability models for the White-breasted ThrasherRamphocinclus brachyurus, a narrowly distributed endangered songbird that occupies dry forest in Saint Lucia and Martinique. Eighty-five percent of the global population inhabits two ranges in Saint Lucia, both of which are largely unprotected and threatened by development. We developed three habitat suitability models using Maxent techniques and published occupancy datasets collected from the species’ two Saint Lucian ranges, and used abiotic, land cover, and predator distribution predictors. We built one model with occupancy data from both ranges, and two others with occupancy data specific to each range. The best full-range model included 11 predictors; high suitability was associated with close proximity to Saint Lucia fer-de-lanceBothrops caribbeausrange, moderately low precipitation, and areas near streams. Our assessment of suitable sites island-wide was more restricted than results from a recent model that considered older land cover data and omitted predator distributions. All sites identified in our full-range model as highly suitable were in or adjacent to the species’ current designated range. The model trained on southern range occurrences predicted zero suitable habitat in the northern range, where the population is much smaller. In contrast, the model trained on northern range occurrences identified areas of moderate suitability within the southern range and patches of moderately suitable habitat in the western part of the island, where no White-breasted Thrashers currently occur. We interpret these results as suggesting that White-breasted Thrashers currently occupy virtually all suitable habitat on the island, that birds in the northern range occupy marginal habitat, or that an important correlate of suitability is missing from the model. Our results suggest that habitat management should focus on currently occupied areas.