bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of analgesic efficacy and safety of bupivacaine plus ketamine versus bupivacaine alone in rectus sheath block for midline laparotomy
Authors: Hassan Shamsul Kamaruljan , Thang Pooi Yee , Muhd Shukeri Wan Fadzlina Wan , Ismet Suki 
Published: October 2024

Background & Objective: Addition of ketamine affects pain modulation through multiple mechanisms and may enhance the analgesic effect of local anesthetics in rectus sheath block (RSB). However, limited studies have evaluated the analgesic efficacy and safety of ketamine added to RSB for midline laparotomy. We aimed to evaluate the analgesic efficacy and safety of ketamine as an adjuvant to 0.25% bupivacaine in ultrasound-guided RSB following major abdominal or gynecological surgery with midline incision.
Methodology: Fifty-four patients of ASA class I−II, aged 18−65 y, who underwent midline laparotomy under general anesthesia were studied. The patients were randomly allocated to two groups: ultrasound-guided RSB was performed in the control group (n = 28) with 40 ml of 0.25% bupivacaine, while in the ketamine group (n = 28) it was performed with 40 ml of 0.25% bupivacaine plus ketamine 1 mg/kg. Postoperatively, both groups received IV morphine patient-controlled analgesia. The Numeric Rating Scale (NRS) pain scores at rest and on movement were assessed at 0, 1, 12 and 24 h postoperatively. The total 24-h postoperative morphine consumption and psychomimetic side effects were recorded.
Results: The mean NRS pain score on movement was significantly lower in the ketamine group at most time points compared to the control group (P < 0.05). The ketamine group had a significantly reduced total 24 h postoperative morphine consumption (14.3 ± 6.55 mg) compared to the control group (21.86 ± 15.46 mg) (P < 0.05). No psychomimetic adverse effects were reported in both groups.
Conclusion: The addition of ketamine to bupivacaine in RSB resulted in effective postoperative analgesia by reducing postoperative pain scores on movement in patients who underwent midline laparotomy. Such combination also reduced postoperative morphine requirement without serious side effects.
Abbreviations: ERAS - Enhanced Recovery After Surgery; LA - Local anesthetics; NRS - Numeric Rating Scale; PAC - Patient-controlled analgesia; RSB - Rectus sheath block;
Key words: adjuvant; Bupivacaine; Ketamine; Laparotomy; Rectus sheath block
Citation: Hassan SK, Thang PY, Wan Shukeri WFWM, Ismet S. Comparison of analgesic efficacy and safety of bupivacaine plus ketamine versus bupivacaine alone in rectus sheath block for midline laparotomy. Anaesth. pain intensive care 2023;27(2):220−226. DOI: 10.35975/apic.v27i2.2188

Received: December 21, 2022; Reviewed: January 17, 2023; Accepted: January 19, 2023
STUDI KUALITATIF PENYEBAB KETIDAKLENGKAPAN REKAM MEDIS PASIEN DI KLINIK TA DENPASAR
Authors: Sariyani Made Dewi , Wasita Rai Riska Resti , Ariyanti Kadek Sri , Dinatha Ngurah Mahendra , Oktawijayanti Putu 
Published: October 2024

Rekam medis adalah dokumen penting bagi fasilitas pelayanan kesehatan, karena segala bentuk informasi terkait tindakan dan pengobatan tercantum dalam rekam medis. Berbagai permasalahan yang terjadi, jika dalam pengisian rekam medis tidak dilakukan secara konsisten dan benar. Klinik TA merupakan salah satu klinik milik swasta yang berada di Denpasar. Hasil studi pendahuluan dengan kordinator klinik, menunjukan bahwa rekam medis di klinik tersebut masih sangat minim sekali pengaturannya, sehingga saat akreditasi tim klinik agak sedikit kesulitan menyiapkannya. Manfaat penelitian ini yaitu sebagai bahan masukan dan evaluasi bagi dokter, perawat dan pimpinan klinik terjadap pentingnya kelengkapan berkas rekam medis pasien di klinik TA. Metode penelitian yang digunakan adalah kualitatif dengan case study. Berdasarkan hasil observasi dokumen rekam medis, ditemukan bahwa belum mempunyai formulir Unit Gawat Darurat (UGD). Pada rekam medis rawat inap terdapat kekurangan formulir yaitu pelayanan lain yang dilakukan oleh tenaga kesehatan tertentu dan formulir kematian. Selian itu, klinik TA belum memiliki SOP pengadaan dan pemusnahan rekam medis. Petugas tidak memiliki buku ekspedisi sebagai alat untuk menegndalikan berkas keluar atau dipinjam. Rekam medis di klinik TA belum elektronik. Adapun simpulan hasil penelitian yaitu ketidaklengakapan rekam medis pasien disebabkan oleh 5M yaitu man, money, methode, machine, dan material. Terdapat faktor penyebab lain yaitu dukungan pimpinan yang kurang terhadap proses rekam medis pasien di Klinik TA.
Hubungan Self Efficacy dengan Academic Burnout pada Mahasiswa yang Menyusun Skripsi di STIKes Santa Elisabeth Medan Tahun 2021
Authors: N. Lilis , Samfriati  , Rahmatsari L. Mei 
Published: October 2024

Tugas akhir sangatlah penting bagi mahasiswa yang sedang menyusun skripsi. Dalam pengerjaan skripsi ini banyak mahasiswa merasa tertekan dan stres, yang kemudian menyebabkan burnout Academic. Dalam mencegah di anjurkan untuk memiliki self efficacy yang tinggi pada setiap mahasiwa sehingga mampu terlindungi dari academic burnout. Tujuan dari penelitian ini untuk mengetahui adalah hubungan self efficacy dengan burnout academic mahasiswa dalam mengerjakan tugas akhir di Sekolah Tinggi Ilmu Kesehatan Santa Elisabeth Medan pada Tahun 2021. Deskriptif korelasi dengan pendekatan cross-sectional penelitian yang digunakan peneliti. Responden berjumlah 52 orang dengan pengambilan sampel menggunakan simple random sampling. Dari uji statistik Spearman rank didapatkan nilai p = 0,000 (p <0,05) dengan r = -0.650, dimana ada hubungan yang kekuatan sedang serta signifikan dan korelasi bernilai negatif dimana self efficacy meningkat sehingga burnout academic menurun, begitu juga jika self efficacy menurun serta academic burnout dapat meningkat. Diharapkan dengan meningkatkan self efficacy maka dapat mengurangi academic burnout pada mahasiswa.
Evaluation and Analysis of the Influence of Aggregate Type on Selected Concrete Properties
Authors: RUTKOWSKA Gabriela , BARYŁKA Adam , ŻÓŁTOWSKI Mariusz , OGRODNIK Paweł 
Published: October 2024

The main objective of the study was to determine the impact of the use of various types of aggregates for C40/50 class concretes used in construction. As part of the research, concrete mixtures containing natural, artificial and recycled aggregates (dolomite, recycled aggregate, lightweight aggregate, basalt) were designed, as well as a reference mix. Selected characteristics of the mixtures were determined – consistency, viscosity, air content, density, as well as strength properties of concrete and frost resistance. Endurance tests were carried out after 2 and 28 days of maturation. Tests of water absorption and depth of penetration of water under pressure were also carried out. Based on the tests carried out, it was found that concrete mixes with a density close to 2321 kg/m³ and an air content of about 2.5% can be optimal in terms of compressive strength. Mixtures with a higher air content, on the other hand, can be beneficial in conditions that require high frost resistance.
Analisis Pengaruh Islamic Corporate Governance (ICG) dan Intellectual Capital (IC) Terhadap Maqashid Syariah Index (MSI) pada Bank Umum Syariah di Indonesia Periode 2018-2022
Authors: Yusmita  , Suwito  , Sinen Kasim 
Published: October 2024

Penelitian ini merupakan penelitian kuantitatif yang bertujuan untuk menguji pengaruh Islamic Corporate Governance(ICG) dan Intellectual Capital (IC) terhadap Maqashid Syariah Index (MSI). Pengukuran ICG dalam penelitian terdiri dari; jumlah rapat dewan komisaris,jumlah rapat dewan direksi, jumlah rapat dewan pengawas syariah, ukuran komite audit, ukuran audit eksternal. Dan untuk pengukuran IC menggunakan iB-VAIC yang diukur dengan ketiga indikatornya yaitu iB-VACA, iB-VAHU, dan iB-STVA. Penelitian ini menggunakan metode pengumpulan data dengan tinjauan pustaka dan dokumentasi. populasi dalam penelitian ini adalah perusahaan perbankan yang terdaftar pada OJK periode tahun 2018-2022, dengan total 10 perusahaan yang menjadi sampel dalam penelitian ini, yang dimana menggunakan teknik purposive sampling dalam pengumpulan sampel. Alat analisis yang digunakan adalah Eviews 12 sebagai alat uji statistik.
Hasil penelitian menunjukkan jumlah rapat dewan komisaris dan ukuran komite audit berpengaruh terhadap maqashid syariah index, sedangkan jumlah rapat dewan direksi, jumlah rapat dewan pengawas syariah, audit eksternal, iB-VAIC, iB-VACA, iB-VAHU, dan iB-STVA tidak berpengaruh terhadap maqashid syariah index.
Makna Zakat dan Infak untuk Pengembangan Usaha Berbasis Syariah
Authors: Nurhayati  , Alimuddin  , Sundari  
Published: October 2024

Penelitian ini bertujuan untuk mengungkap secara mendalam makna zakat dan infak untuk pengembangan usaha berbasis syariah. Penelitian ini menggunakan metode kualitatif dengan pendekatan interpretif fenomenologi dalam menganalisis makna zakat dan infak untuk pengembangan usaha berbasis syariah di PT Intan Nirwana Nusantara. Data diperoleh dengan melalui pengamatan berpartisipasi pasif, dokumentasi serta melakukan tinjauan literasi dari berbagai sumber. Hasil penelitian menunjukkan bahwa nilai ridho dan nilai amanah sebagai manifestasi dalam aktivitas usaha. Berdasarkan temuan penelitian, nilai zakat dan infak di PT. Intan Nirwana Nusantara tidak hanya diartikan sebagai kewajiban finansial semata melainkan memiliki makna yang lebih luas. Zakat dan infak diinterpretasikan sebagai instrumen untuk mencapai tujuan pembangunan ekonomi berbasis syariah dan sebagai simbol kesadaran sosial, kemanusiaan serta kepatuhan terhadap perintah Allah SWT. Pemberian zakat dan infak di perusahaan tersebut tidak hanya memberikan nilai tambah materiil seperti peningkatan modal usaha dan pembangunan lokasi perumahan tetapi juga memberikan nilai tambah spiritual.
Utilization of Nanotechnology in Metformin Delivery: The Morphometric Study of Pancreatic Islets of Diabetic Rat Model
Authors: Pakaya David , Fahira Aliyah Rezky , Anwar Sarifuddin , Lintin Gabriella Bamba Ratih 
Published: October 2024

Introduction: In diabetic conditions, damage of β cells and changes the structure of pancreatic islets was exhibited. Metformin can improve this condition. The nanoparticle form of metformin can improve bioavailability and accelerate cell regeneration, and pancreatic islets can be repaired. The aim of this study to know the effect of nanoparticles metformin on fasting blood glucose levels and pancreatic islet morphometry in diabetic rat models.Method: An experimental research with posttest-only controlled group design was conducted on 16 white male Wistar rats. The streptozotocin (STZ) 40 mg/kgBB were injected i.p. Rats were divided into four groups: K1: normal control; K2: negative control (diabetes model); K3: diabetes model treated with metformin 100mg/kgBB; K4: diabetes model treated with nanoparticle metformin 100mg/kgBB. The body weight and fasting blood glucose levels were measured periodically. The histology of pancreatic islets was performed with hematoxylin-eosin staining and quantified using ImageJ software. The data were analyzed with GraphPad Prism 8.0.0 using nonparametric Kruskal-Wallis test.Results: Metformin therapy decreased the fasting blood glucose levels in K3 starting on day 21 and K4 starting on day 7, but there was no statistical difference (p=0.0597). Pancreatic islet morphometry showed the pancreatic islet area was found to be statistically different (p=0.026), and the perimeter was not statistically different (p=0.115).Conclusion: Metformin nanoparticle form decreased the fasting blood glucose levels and effectively improved the area and perimeter of pancreatic islets of the diabetic rats model, but the perimeter of the pancreatic islets is not statistically significant.Keywords: Diabetes, metformin, nanoparticles, pancreatic islets, morphometry.
Characteristics of Lower Urinary Tract Symptoms (LUTS) in the Chronic Disease Management Program (Program Pengelolaan Penyakit Kronis, PROLANIS) Patients: A Pilot Study in Gorontalo Province
Authors: Ibrahim Sri A , Hasanuddin Abdi Dzul Ikram 
Published: October 2024

Introduction: Lower Urinary Tract Symptoms (LUTS) are common in older adults and significantly impact individuals, caregivers, and the broader healthcare system. As the elderly population with various comorbidities increases, the burden of LUTS will increase. The chronic disease management program (Program Pengelolaan Penyakit Kronis, PROLANIS) is a government program generally followed by the elderly. This study aims to describe the characteristics of LUTS in PROLANIS patients in Gorontalo Province.Methods: The analytical observational study design, using a cross-sectional approach, was conducted on PROLANIS patients living in rural and urban areas in Gorontalo Province is between July - October 2023. An incidental sampling technique was conducted on eligible patients and areas. LUTS symptoms were measured using the International Prostate Symptom Score (IPSS) questionnaire and categorized into mild, moderate, and severe. LUTS symptoms were considered significant if the IPSS score was ≥8.Results: Of the 52 participants, 38.50% experienced significant LUTS symptoms. The majority of symptoms felt were nocturia (score two, as many as 23.10%) and mild symptoms (53.80%). Geographical differences, gender, education level, and age were not associated with LUTS symptoms (p 0.10).Conclusion: The prevalence of LUTS in patients undergoing PROLANIS is relatively high. The majority of LUTS patients have mild symptoms, with nocturia being the most common complaint compared to other symptoms. Further studies with a larger sample size and involving multiple sites are needed to obtain a more valid description of the characteristics of LUTS epidemiology in the PROLANIS population. Keywords: Aged; Disease Management; Lower Urinary Tract Symptoms; Nocturia
TOI 762 A b and TIC 46432937 b: Two Giant Planets Transiting M-dwarf Stars
Authors: Hartman Joel D. , Bayliss Daniel , Brahm Rafael , Bryant Edward M. , Jordán Andrés , Bakos Gáspár Á. , Hobson Melissa J. , Sedaghati Elyar , Bonfils Xavier , Cointepas Marion , Almenara Jose Manuel , Barkaoui Khalid , Timmermans Mathilde , Dransfield George , Ducrot Elsa , Zúñiga-Fernández Sebastián , Hooton Matthew J. , Pedersen Peter Pihlmann , Pozuelos Francisco J. , Triaud Amaury H. M. J. , Gillon Michaël , Jehin Emmanuel , Waalkes William C. , Berta-Thompson Zachory K. , Howell Steve B. , Furlan Elise , Ricker George R. , Vanderspek Roland , Seager Sara , Winn Joshua N. , Jenkins Jon M. , Rapetti David , Collins Karen A. , Charbonneau David , Burke Christopher J. , Rodriguez David R. 
Published: October 2024

Abstract
We present the discovery of TOI 762 A b and TIC 46432937 b, two giant planets transiting M-dwarf stars. Transits of both systems were first detected from observations by the NASA TESS mission, and the transiting objects are confirmed as planets through high-precision radial velocity observations carried out with Very Large Telescope/ESPRESSO. TOI 762 A b is a warm sub-Saturn with a mass of 0.251 ± 0.042 M
J, a radius of 0.744 ± 0.017 R
J, and an orbital period of 3.4717 days. It transits a mid-M-dwarf star with a mass of 0.442 ± 0.025 M
☉ and a radius of 0.4250 ± 0.0091 R
☉. The star TOI 762 A has a resolved binary star companion, TOI 762 B, that is separated from TOI 762 A by 3.″2 (∼319 au) and has an estimated mass of 0.227 ± 0.010 M
☉. The planet TIC 46432937 b is a warm super-Jupiter with a mass of 3.20 ± 0.11 M
J and radius of 1.188 ± 0.030 R
J. The planet’s orbital period is P = 1.4404 days, and it undergoes grazing transits of its early M-dwarf host star, which has a mass of 0.563 ± 0.029 M
☉ and a radius of 0.5299 ± 0.0091 R
☉. TIC 46432937 b is one of the highest-mass planets found to date transiting an M-dwarf star. TIC 46432937 b is also a promising target for atmospheric observations, having the highest transmission spectroscopy metric or emission spectroscopy metric value of any known warm super-Jupiter (mass greater than 3.0 M
J, equilibrium temperature below 1000 K).
Structured Jet Model for Multiwavelength Observations of the Jetted Tidal Disruption Event AT 2022cmc
Authors: Yuan 袁 Chengchao 成超 , Zhang 张 B. Theodore 兵 , Winter Walter , Murase Kohta 
Published: October 2024

Abstract
AT 2022cmc is a recently documented tidal disruption event that exhibits a luminous jet, accompanied by fast-declining X-ray and long-lasting radio and millimeter emission. Motivated by the distinct spectral and temporal signatures between the X-ray and radio observations, we propose a multizone model involving relativistic jets with different Lorentz factors. We systematically study the evolution of faster and slower jets in an external density profile, considering the continuous energy injection rate associated with time-dependent accretion rates before and after the mass fallback time. We investigate time-dependent multiwavelength emission from both the forward shock (FS) and reverse shock (RS) regions of the fast and slow jets, in a self-consistent manner. Our analysis demonstrates that the energy injection rate can significantly impact the jet evolution and subsequently influence the lightcurves. We find that the X-ray spectra and lightcurves could be described by electron synchrotron emission from the RS of the faster jet, in which the late-time X-ray upper limits, extending to 400 days after the disruption, could be interpreted as a jet break. Meanwhile, the radio observations can be interpreted as a result of synchrotron emission from the FS region of the slower jet. We also discuss prospects for testing the model with current and future observations.
The Origins of Narrow Spectra of Fast Radio Bursts
Authors: Kumar Pawan , Qu Yuanhong , Zhang Bing 
Published: October 2024

Abstract
Observations find that some fast radio bursts (FRBs) have extremely narrowband spectra, i.e., Δν/ν
0 ≪ 1. We show that, when the angular size of the emission region is larger than the Doppler beaming angle, the observed spectral width (Δν/ν
0) exceeds 0.58 due to the high-latitude effects for a source outside the magnetosphere, even when the spectrum in the source’s comoving frame is monochromatic. The angular size of the source for magnetospheric models of FRBs can be smaller than the Doppler beaming angle, in which case this geometric effect does not influence the observed bandwidth. We discuss various propagation effects to determine if any could transform a broad-spectrum radio pulse into a narrow spectrum signal at the observer’s location. We find that plasma lensing and scintillation can result in a narrow bandwidth in the observed spectrum. However, the likelihood of these phenomena being responsible for the narrow observed spectra with Δν/ν
0 < 0.58 in the fairly large observed sample of FRBs is exceedingly small.
Stripe 82-XL: The ∼54.8 deg2 and ∼18.8 Ms Chandra and XMM-Newton Point-source Catalog and Number of Counts
Authors: Peca Alessandro , Cappelluti Nico , LaMassa Stephanie , Urry C. Megan , Moscetti Massimo , Marchesi Stefano , Sanders David , Auge Connor , Ghosh Aritra , Ananna Tonima Tasnim , Torres-Albà Núria , Treister Ezequiel 
Published: October 2024

Abstract
We present an enhanced version of the publicly available Stripe 82X catalog (S82-XL), featuring a comprehensive set of 22,737 unique X-ray point sources identified with a significance ≳4σ. This catalog is four times larger than the original Stripe 82X catalog, by including additional archival data from the Chandra and XMM-Newton telescopes. Now covering ∼54.8 deg2 of nonoverlapping sky area, the S82-XL catalog roughly doubles the area and depth of the original catalog, with limiting fluxes (half-area fluxes) of 3.4 × 10−16 (2.4 × 10−15), 2.9 × 10−15 (1.5 × 10−14), and 1.4 × 10−15 (9.5 × 10−15) erg s−1 cm−2 across the soft (0.5–2 keV), hard (2–10 keV), and full (0.5–10 keV) bands, respectively. S82-XL occupies a unique region of flux-area parameter space compared to other X-ray surveys, identifying sources with rest-frame luminosities from 1.2 × 1038 to 1.6 × 1047 erg s−1 in the 2–10 keV band (median X-ray luminosity, 7.2 × 1043 erg s−1), and spectroscopic redshifts up to z ∼ 6. By using hardness ratios, we derived the obscuration of active galactic nuclei (AGNs), obtaining a median value of

log

(

N

H

/

cm

−
2

)
=

21.6

−
1.6

+
1.0

and an overall, obscured fraction (

log

(

N

H

/

cm

−
2

)
>
22

) of ∼36.9%. S82-XL serves as a benchmark in X-ray surveys and, with its extensive multiwavelength data, is especially valuable for comprehensive studies of luminous AGNs.
The Anisotropic Circumgalactic Medium of Sub-L* Galaxies
Authors: Zhang 张 Huanian 华年 , Li 李 Miao 邈 , Zaritsky Dennis 
Published: October 2024

Abstract
Using stacked emission-line flux measurements of cool circumgalactic gas (CGM) in lower-mass galaxies (109.0 ≤ M
*/M
⊙ ≤ 1010.2), we measure the dependence of the emission characteristics on orientation relative to the disk plane as a function of radius and compare to what we found previously for massive (M
* > 1010.4
M
⊙) early-type galaxies. Although the line ratios (the lower [N ii]/Hα and [O iii]/Hβ) suggest an overall softer ionizing source than in the more massive galaxies, consistent with previous findings, we find the same ionization hardening signature (a higher [N ii]/Hα ratio in the inner polar region) along the polar direction at small radii that we found for the more massive galaxies. The line ratio in the inner polar bin is distinct from that measured for the inner planar bin with 99.99%, confidence and with >99.9% confidence we conclude that it lies outside the star formation regime. The effective hardening of the ionization of the CGM along the polar axis, at small radii, could indicate either relic effects of active galactic nucleus activity or shock ionization. In either case, this signature appears to be ubiquitous across the stellar mass range we are able to explore with our spectral stacking technique and currently available archival data.
Indication of Sharp and Strong Phase Transitions from NICER Observations
Authors: Lin Zidu , Steiner Andrew. W. 
Published: October 2024

Abstract
In this Letter, we present a new, weakly model-dependent test for “standard” equation-of-state (EoS) models that disfavor sharp and strong phase transitions by using NS mass and radius observations. We show the radii of two NSs observed by NICER (PSR J0740+6620 and PSR 0030+0451) are correlated if these two NSs are built upon standard EoS models. The radii of NSs with different masses are sensitive to the pressures at different densities, and the pressures at different densities are strongly correlated in standard EoS models. We further show that the correlation of the NS radii can be significantly weakened when additional degrees of freedom concerning the first-order phase transitions are added into the EoSs. We propose a new quantity, D
L, which measures the extent to which the linear correlation of the radii of two NSs is weakened. Our method gives a 48% identification probability (with a 5% false alarm rate) of finding beyond-standard EoS models in NICER observations. Future observations with higher measurement accuracy can confirm or rule out this identification. Our method is generalizable to any pair of NS masses and can be employed with other sets of observations in the future.