bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fiber up‐sampling and quality assessment of tractograms – towards quantitative brain connectivity
Authors: Sommer Stefan , Kozerke Sebastian , Seifritz Erich , Staempfli Philipp 
Published: October 2016

AbstractBackground and PurposeDiffusion MRI tractography enables to investigate white matter pathways noninvasively by reconstructing estimated fiber pathways. However, such tractograms remain biased and nonquantitative. Several techniques have been proposed to reestablish the link between tractography and tissue microstructure by modeling the diffusion signal or fiber orientation distribution (FOD) with the given tractogram and optimizing each fiber or compartment contribution according to the diffusion signal or FOD. Nevertheless, deriving a reliable quantification of connectivity strength between different brain areas is still a challenge. Moreover, evaluating the quality of a tractogram and measuring the possible error sources contained in a specific reconstructed fiber bundle also remains difficult. Lastly, all of these optimization techniques fail if specific fiber populations within a tractogram are underrepresented, for example, due to algorithmic constraints, anatomical properties, fiber geometry or seeding patterns.MethodsIn this work, we propose an approach which enables the inspection of the quality of a tractogram optimization by evaluating the residual error signal and its FOD representation. The automated fiber quantification (AFQ) is applied, whereby the framework is extended to reflect not only scalar diffusion metrics along a fiber bundle, but also directionally dependent FOD amplitudes along and perpendicular to the fiber direction. Furthermore, we also present an up‐sampling procedure to increase the number of streamlines of a given fiber population. The introduced error metrics and fiber up‐sampling method are tested and evaluated on single‐shell diffusion data sets of 16 healthy volunteers.Results and ConclusionAnalyzing the introduced error measures on specific fiber bundles shows a considerable improvement in applying the up‐sampling method. Additionally, the error metrics provide a useful tool to spot and identify potential error sources in tractograms.
Synergistic Catalysis for the Asymmetric [3+2] Cycloaddition of Vinyl Aziridines with α,β‐Unsaturated Aldehydes
Authors: Næsborg Line , Tur Fernando , Meazza Marta , Blom Jakob , Halskov Kim Søholm , Jørgensen Karl Anker 
Published: October 2016

AbstractThe first asymmetric [3+2] cycloaddition of vinyl aziridines with α,β‐unsaturated aldehydes, based on synergistic catalysis, is disclosed. This methodology allows the formation of attractive pyrrolidine structures in good yields (up to 84 %), moderate diastereoselectivity, and high enantioselectivity values (up to >99 % ee). Additionally, a tricyclic pyrrolidine core structure found in biologically active molecules was synthesized in a one‐pot fashion by using the presented reaction concept. Finally, a mechanistic proposal is outlined.
Single‐Step Synthesis of Organometallic Molecular Squares from NR,NR′,NR′′,NR′′′‐Substituted Benzobiscarbenes
Authors: Sinha Narayan , Roelfes Florian , Hepp Alexander , Hahn F. Ekkehardt 
Published: October 2016

AbstractThe single‐step multicomponent self‐assembly of molecular squares featuring four bridging benzobiscarbenes and four PdII(allyl) or IrI(COD) vertices is presented. Four equivalents of the linear benzobisimidazolium salt [1](PF6)2 react with two equivalents of [Pd(allyl)Cl]2 or [IrCl(COD)]2 in the presence of Cs2CO3 to yield the tetranuclear octacarbene molecular squares [2](PF6)4 (M=Pd) and [3](PF6)4 (M=Ir), respectively. Compounds [2](PF6)4 and [3](PF6)4 feature exclusively M–carbon bonds making them the first purely organometallic molecular squares.
ChemInform Abstract: Investigation of the Transport Properties and Compositions of the Ca2RE7Pn5O5 Series (RE: Pr, Sm, Gd, Dy; Pn: Sb, Bi).
Authors: Forbes Scott , Yuan Fang , Kosuda Kosuke , Kolodiazhnyi Taras , Mozharivskyj Yurij 
Published: October 2016

AbstractThe title Ca‐substituted phases are prepared by r.f.
ChemInform Abstract: Synthesis, Crystal Structure, and Magnetic Properties of Quaternary Iron Selenides: Ba2FePnSe5 (Pn: Sb, Bi).
Authors: Wang Jian , Greenfield Joshua T. , Kovnir Kirill 
Published: October 2016

AbstractBa2FeSbSe5 (I) and Ba2FeBiSe5 (II) are prepared by solid state reaction of Ba, Fe, Sb (Bi), and Se in molar ratios of 2:1:1:5 (carbonized evacuated silica tubes, 1073 K, 144 h).
ChemInform Abstract: Synthesis, Structure and Electrochemical Properties of LiNaCo0.5Fe0.5PO4F Fluoride—Phosphate.
Authors: Fedotov Stanislav S. , Kuzovchikov Sergey M. , Khasanova Nellie R. , Drozhzhin Oleg A. , Filimonov Dmitriy S. , Karakulina Olesia M. , Hadermann Joke , Abakumov Artem M. , Antipov Evgeny V. 
Published: October 2016

AbstractThe title compound is synthesized by solid state reaction of stoichiometric amounts of LiCo0.5Fe0.5PO4 and NaF (1.
ChemInform Abstract: Synthesis, Crystal Structure and Electrical Properties of the Tetrahedral Quaternary Chalcogenides CuM2InTe4 (M: Zn, Cd).
Authors: Nolas George S. , Hassan M. Shafiq , Dong Yongkwan , Martin Joshua 
Published: October 2016

AbstractPolycrystalline samples of CuZn2InTe4 (I) and CuCd2InTe4 (II) are prepared by solid state reaction of stoichiometric amounts of the elements (silica tubes in evacuated quartz tubes, 973 k, 4 d) and subsequent annealing (873 K (I) or 723 K (II), 21 d) and hot press sintering (723 K (I) or 623 K (II), 150 MPa, 3 h).
ChemInform Abstract: From Racemic Precursors to Fully Stereocontrolled Products: One‐Pot Synthesis of Chiral α‐Amino Lactones and Lactams.
Authors: You Zhi‐Hao , Chen Ying‐Han , Liu Yan‐Kai 
Published: October 2016

AbstractAn asymmetric α‐amination of racemic lactols or cyclic hemiaminals with azodicarboxylates followed by oxidation yields chiral α‐amino lactones or lactams with excellent enantioselectivities.
ChemInform Abstract: Calcium Complexes with Imino‐Phosphinanilido Chalcogenide Ligands for Heterofunctionalisation Catalysis.
Authors: Anga Srinivas , Carpentier Jean‐Francois , Panda Tarun K. , Roisnel Thierry , Sarazin Yann 
Published: October 2016

AbstractThe novel calcium complex ligands (I) show good performance in the anti‐Markovnikov hydrophosphination of styrene, but low activity in the hydroamination reaction.
ChemInform Abstract: Efficient Ullmann C—N Coupling Catalyzed by a Recoverable Oligose‐Supported Copper Complex.
Authors: Ge Xin , Chen Xinzhi , Qian Chao , Zhou Shaodong 
Published: October 2016

AbstractA β‐cyclodextrin supported copper complex is successfully employed as catalyst for the coupling reaction of various N‐nucleophiles and aryl halides.
ChemInform Abstract: N‐Arylation of Nitrogen Containing Heterocycles with Aryl Halides Using Copper Nanoparticle Catalytic System.
Authors: Pai Gita , Chattopadhyay Asoke P. 
Published: October 2016

AbstractBoth aryl iodides and aryl bromides are compatible with the reaction conditions; with bromides giving somewhat lower yields.
ChemInform Abstract: Benzene‐1,3,5‐triyl Triformate (TFBen): A Convenient, Efficient, and Non‐reacting CO Source in Carbonylation Reactions.
Authors: Jiang Li‐Bing , Qi Xinxin , Wu Xiao‐Feng 
Published: October 2016

AbstractThe synthesis of benzene‐1,3,5‐triyl triformate (III) is developed and its utility as CO source in different Pd‐catalyzed coupling reactions is demonstrated.
ChemInform Abstract: Additional Nucleophile‐Free FeCl3‐Catalyzed Green Deprotection of 2,4‐Dimethoxyphenylmethyl‐Protected Alcohols and Carboxylic Acids.
Authors: Sawama Yoshinari , Masuda Masahiro , Honda Akie , Yokoyama Hiroki , Park Kwihwan , Yasukawa Naoki , Monguchi Yasunari , Sajiki Hironao 
Published: October 2016

AbstractThe title transformation is performed on a broad range of variously functionalized 2,4‐dimethoxyphenylmethyl‐protected alcohols and carboxylic acids.
ChemInform Abstract: The Organocatalytic α‐Fluorination of Chiral γ‐Nitroaldehydes: The Challenge of Facing the Construction of a Quaternary Fluorinated Stereocenter.
Authors: Emma Marco Giuseppe , Lombardo Marco , Trombini Claudio , Quintavalla Arianna 
Published: October 2016

AbstractThe organocatalytic fluorination of γ‐nitroaldehydes with N‐fluorobenzenesulfonimide allows for the highly stereoselective construction of a challenging quaternary fluorinated stereocenter at the α position of α,α‐dialkyl aldehydes.
ChemInform Abstract: Sulfinamide Phosphinates as Chiral Catalysts for the Enantioselective Organocatalytic Reduction of Imines.
Authors: Chelouan Ahmed , Recio Rocio , Borrego Lorenzo G. , Alvarez Eleuterio , Khiar Noureddine , Fernandez Inmaculada 
Published: October 2016

AbstractThe reaction tolerates diverse arylmethyl imines while delivering the corresponding arylmethyl amines in high yields and with high enantiomeric excesses.
ChemInform Abstract: Enhanced Structural Variety of Nonplanar N‐Oxyl Radical Catalysts and Their Application to the Aerobic Oxidation of Benzylic C—H Bonds.
Authors: Kadoh Yoichi , Oisaki Kounosuke , Kanai Motomu 
Published: October 2016

AbstractThe reaction has a broad substrate scope and provides the products in moderate to high yields.
ChemInform Abstract: Investigation on Palladium‐Catalyzed α‐Oxidation of Aromatic Ketones.
Authors: Chen Tianbao , Ren Hexiang , Zhang Ming , Zhang Ai Qin 
Published: October 2016

AbstractThe α‐acetoxylation of aromatic ketones using (diacetoxyiodo)benzene as oxidant and palladium acetate as catalyst is described.
ChemInform Abstract: Visible Light Catalyzed Methylsulfoxidation of (Het)aryl Diazonium Salts Using DMSO.
Authors: Pramanik Mukund M. D. , Rastogi Namrata 
Published: October 2016

AbstractThis photocatalyzed methylsulfoxidation of aromatic diazonium salts with DMSO provides aryl methyl sulfoxides in excellent yields under mild reaction conditions and tolerates a wide range of functional groups.
ChemInform Abstract: An Improved Suzuki—Miyaura Cross‐Coupling Reaction with the Aid of in situ Generated PdNPs: Evidence for Enhancing Effect with Biphasic System.
Authors: Mahanta Abhijit , Mondal Manoj , Thakur Ashim Jyoti , Bora Utpal 
Published: October 2016

AbstractAn improved procedure for the Suzuki—Miyaura cross‐coupling in a water extract of rice straw ash is presented.
ChemInform Abstract: Palladium and Copper Catalyzed Sonogashira Decarboxylative Coupling of Aryl Iodides and Alkynyl Carboxylic Acids.
Authors: Maaliki Carine , Chevalier Yoan , Thiery Emilie , Thibonnet Jerome 
Published: October 2016

AbstractEfficient microwave promoted reaction conditions are developed for the decarboxylative Sonogashira coupling of propiolic acids with aryl iodides.
ChemInform Abstract: Metal‐Free Oxidative Annulation of 2‐Naphthols with Terminal Alkynes Affording 2‐Arylnaphtho[2,1‐b]furans.
Authors: Liu Long , Ji Xuyu , Dong Jianyu , Zhou Yongbo , Yin Shuang‐Feng 
Published: October 2016

AbstractThe scalable reaction is successfully performed starting from functionalized 2‐naphthols and aryl alkynes, but fails using 1‐naphthol, phenol or biphenol and alkyl substituted or internal alkynes.
ChemInform Abstract: 5‐Aryl‐2‐(2‐hydroxyphenyl)furan‐3‐carbaldehyde: Synthesis and Study on Its Ring‐Chain Tautomerism.
Authors: Ghosh Jaydip , Biswas Pritam , Sarkar Tapas , Drew Michael G. B. , Bandyopadhyay Chandrakanta 
Published: October 2016

AbstractAlkylchromones are found to undergo a AgNO3‐catalyzed isomerization to furanaldehydes which can exist in solution as tautomeric mixtures with lactols.
ChemInform Abstract: Wittig—Horner Mediated Synthesis of 4‐Vinyl Sulfide Derivatives of Pyrazoles.
Authors: Padilha Gustavo , Kaufman Teodoro S. , Silveira Claudio C. 
Published: October 2016

AbstractBuLi‐mediated Wittig—Horner reactions of 4‐formylpyrazoles with arylthiophosphonates result in a synthesis of E/Z‐mixtures of 4‐vinyl sulfide derivatives.
ChemInform Abstract: Palladium‐Catalyzed Carbonylative Coupling of α‐Chloroketones with Hydrazines: A Simple Route to Pyrazolone Derivatives.
Authors: Capua Martina , Granito Catia , Perrone Serena , Salomone Antonio , Troisi Luigino 
Published: October 2016

AbstractThe title reaction is examined to generally give mixtures of regioisomeric pyrazolones.
ChemInform Abstract: Fe(OTf)3‐Catalyzed Practical Synthesis of 2‐Trifluoromethylarylimidazoles from O‐Arylenediamines and Hexafluoroacetylacetone.
Authors: Zhou Yanmei , Shen Guanshuo , Sui Yuebo , Zhou Haifeng 
Published: October 2016

AbstractFe(OTf)3‐catalyzed condensation of o‐phenylenediamine and hexafluoroacetylacetone results in an efficient formation of 2‐trifluoromethyl substituted benzimidazoles.
ChemInform Abstract: An Efficient Passerini Tetrazole Reaction (PT‐3CR).
Authors: Chandgude Ajay L. , Doemling Alexander 
Published: October 2016

AbstractThe ultrasound‐mediated catalyst‐free Passerini‐type reaction of carbonyl compounds (I) and (IV) with isocyanides (II) and trimethylsilyl azide gives rise to tetrazoles (III) and (V).
ChemInform Abstract: Rh(III)‐Catalyzed C—H Activation/Cyclization of Oximes with Alkenes for Regioselective Synthesis of Isoquinolines.
Authors: Chen Renjie , Qi Jifeng , Mao Zhenjun , Cui Sunliang 
Published: October 2016

AbstractA regioselective cyclization of oximes with alkenes affords isoquinolines under mild reaction conditions.
ChemInform Abstract: An Improved Procedure for the Three‐Component Synthesis of 1H‐Pyrazolo[1,2‐b]phthalazine‐5,10‐dione Derivatives Using Basic Ionic Liquid.
Authors: Wang Wang , Li Cong‐Hao , Yi Yu , Li Xiao‐Jun , Guo Hong‐Yun 
Published: October 2016

AbstractThe title compounds are prepared by three‐component cyclocondensation of phtalhydrazide, benzaldehydes, and malononitrile or ethyl cyanoacetate under environmentally friendly conditions.
ChemInform Abstract: Pd‐Catalyzed and Copper Assisted Regioselective Sequential C2 and C7 Arylation of Thiazolo[5,4‐f]quinazolin‐9(8H)‐one with Aryl Halides.
Authors: Harari Marine , Couly Florence , Fruit Corinne , Besson Thierry 
Published: October 2016

AbstractThe synthetically useful title transformation is performed in a convenient one‐pot manner.
ChemInform Abstract: Cyclization of 2‐Ethynylphenyl Vinyl Ether Catalyzed by a Ruthenium Complex: Mechanism of Catalytic Cyclization and Stoichiometric Cycloisomerization.
Authors: Chen Chi‐Ren , Lai Ying‐Xuan , Wu Rong‐Yu , Liu Yi‐Hung , Lin Ying‐Chih 
Published: October 2016

AbstractFour vinyl ethers are investigated as cyclization precursors in the presence of a Ru‐catalyst using 1:1 alcohol/dichloromethane mixtures.
ChemInform Abstract: Palladium‐Catalyzed C—P(III) Bond Formation Reaction with Acylphosphines as Phosphorus Source.
Authors: Yu Rongrong , Chen Xingyu , Wang Zhiqian 
Published: October 2016

AbstractA Pd‐catalyzed coupling of aryl halides and triflates with acylphosphines is developed to provide a convenient synthesis of triorganylphosphines having at least two different substituents.
ChemInform Abstract: Hyrtinadines C and D, New Azepinoindole‐Type Alkaloids from a Marine Sponge Hyrtios sp.
Authors: Kubota Takaaki , Nakamura Kenta , Sakai Kanae , Fromont Jane , Gonoi Tohru , Kobayashi Jun'ichi 
Published: October 2016

AbstractThe antimicrobial activity of (Ia,b) is examined.
ChemInform Abstract: Neolignans from the Fruits of Magnolia obovata Inhibit NO Production and Have Neuroprotective Effects.
Authors: Seo Kyeong‐Hwa , Lee Dae‐Young , Jung Jae‐Woo , Lee Dong‐Sung , Kim Youn‐Chul , Lee Youn‐Hyung , Baek Nam‐In 
Published: October 2016

AbstractThe title compounds, obovatalignan A (I) and B (II), exhibit protective effects against glutamate‐induced oxidative stress, as well as inhibitory effects on the NO production.
Neutrophil‐to‐lymphocyte ratio as a bladder cancer biomarker: Assessing prognostic and predictive value in SWOG 8710
Authors: Ojerholm Eric , Smith Andrew , Hwang Wei‐Ting , Baumann Brian C. , Tucker Kai N. , Lerner Seth P. , Mamtani Ronac , Boursi Ben , Christodouleas John P. 
Published: October 2016

BACKGROUNDRisk stratification is a major challenge in bladder cancer (BC), and a biomarker is needed. Multiple studies have reported the neutrophil‐to‐lymphocyte ratio (NLR) as a promising candidate; however, these analyses have methodological limitations. Therefore, the authors performed a category B biomarker study to test whether NLR is prognostic for overall survival (OS) after curative treatment or is predictive for the survival benefit from neoadjuvant chemotherapy (NAC).METHODSThis study is an unplanned secondary analysis of SWOG 8710, a randomized phase 3 trial that assessed cystectomy with or without NAC in 317 patients with muscle‐invasive BC. NLR was calculated from prospectively collected complete blood counts. For the prognostic analysis, 230 patients were identified; for the predictive analysis, 263 were identified. NLR was evaluated with proportional hazards models including prespecified factors (age, sex, T‐stage, lymphovascular invasion, and treatment arm).RESULTSWith a median follow‐up of 18.6 years, there were 172 and 205 deaths in the prognostic and predictive cohorts, respectively. In a multivariable analysis, NLR was not prognostic for OS (hazard ratio [HR], 1.04; 95% confidence interval [CI], 0.98‐1.11; P = .24). Furthermore, NLR did not predict for the OS benefit from NAC (HR, 1.01; 95% CI, 0.90‐1.14; P = .86). Factors associated with worse OS were older age (HR, 1.05; 95% CI, 1.04‐1.07; P < .001) and surgery without NAC (HR, 1.39; 95% CI, 1.03‐1.88; P = .03).CONCLUSIONSThis is the first analysis of NLR in BC to use prospectively collected clinical trial data. In contrast to previous studies, it suggests that NLR is neither a prognostic nor predictive biomarker for OS in muscle‐invasive BC. Cancer 2017;123:794–801. © 2016 American Cancer Society.
Color appearance modeling of bicolor striped woven fabrics considering neighboring color effects
Authors: Chae Youngjoo , Xin John H. , Hua Tao , Luo Mei 
Published: October 2016

AbstractIn this article, the effect of the spatial and colorimetric attributes of neighboring color on color appearance shift in bicolor striped woven fabrics is investigated. A total of 240 test/neighboring woven color combinations were constructed in four different striped paradigms. Each test color in the combinations was visually assessed by 12 observer panels with the use of the magnitude estimation method estimating the magnitude of perceptual color attributes lightness, colorfulness, and hue. The visual estimates obtained were analyzed statistically by employing correlation and simple regression methods, and, as a result, the following significant neighboring color effects were detected and individually defined: (1) neighboring color's size, lightness, colorfulness, and hue on test color's lightness, (2) neighboring color's colorfulness and hue on test color's colorfulness, and (3) neighboring color's hue on test color's hue. Furthermore, through multiple regression analysis, color appearance models by which the lightness, colorfulness, and hue of bicolor woven fabrics can be predicted were derived. The predictive performance of the models was evaluated by calculating the difference between the visually estimated and the predicted color appearances, using ΔL*, ΔC*, Δh°, and ΔECMC(2:1). Among all the derived models, the model producing the smallest mean error was chosen as a final model, and its great accuracy in color appearance predictions was verified through further statistical evaluation. It is envisaged that the findings of this research are of benefit to design textile products with bicolor striped woven fabrics to have desired color appearances. © 2016 Wiley Periodicals, Inc. Col Res Appl, 42, 512–521, 2017
A novel approach for energy‐efficient resource allocation in double threshold‐based cognitive radio network
Authors: Das Deepa , Das Susmita 
Published: October 2016

SummaryThis paper mainly focuses on solving the energy efficiency (EE) maximization problem in double threshold‐based soft decision fusion (SDF) cooperative spectrum sensing (CSS) in the cognitive radio network (CRN). The solution to this objective problem starts with the selection of suitable secondary users (SUs) both for the spectrum sensing and data transmission. Here, energy efficiency is maximized under the constraints of interference to the primary user (PU), an acceptable outage of SUs, the transmission power of the SUs and the probability of false alarm. We propose a novel algorithm called iterative Dinkelbach method (IDM) which jointly optimizes the sensing time and transmission power allocation to the SUs. Further, Lagrangian duality theorem is employed to find the exact power assigned to the SUs. Finally, simulation results are carried out to validate the effectiveness of our proposed scheme by comparing with the other existing schemes. The performance is also analyzed for different system parameters.
Negative effects of density on space use of small mammals differ with the phase of the masting‐induced population cycle
Authors: Bogdziewicz Michał , Zwolak Rafał , Redosh Lauren , Rychlik Leszek , Crone Elizabeth E. 
Published: October 2016

AbstractHome range size generally decreases with increasing population density, but testing how this relationship is influenced by other factors (e.g., food availability, kin structure) is a difficult task. We used spatially explicit capture–recapture models to examine how home range size varies with population density in the yellow‐necked mouse (Apodemus flavicollis). The relationship between population density and home range size was studied at two distinct phases of population fluctuations induced by beech (Fagus sylvatica) masting: post‐mast peak in abundance (first summer after mast, n = 2) and subsequent crash (second summer after mast, n = 2). We live‐trapped mice from June to September to avoid the confounding effects of autumn seedfall on home range size. In accordance with general predictions, we found that home range size was negatively associated with population density. However, after controlling for the effect of density, home ranges of mice were larger in post‐mast years than during the crash phase. This indicates a higher spatial overlap among neighbors in post‐mast years. We suggest that the increased spatial overlap is caused by negative density‐dependent dispersal that leads to high relatedness of individuals within population in the peak phase of the cycle.