bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Gaya Kepemimpinan terhadap Motivasi dan Dampaknya terhadap Kinerja Sumber Daya Manusia
Authors: Resky Resky , Kuncoro Engkos Achmad 
Published: October 2016

PT Bukit Asam (Persero) Tbk (PTBA) is a state-owned companies in the field of the largest coal mine in Indonesia. The purpose of this study was to determine how much influence the leadership style to employee motivation human resource Human Resources Division, how much influence employee motivation to employee performance Human Resources Division Human Resources Division and how much influence the style of Leadership Human Resources Division directly or indirectly against employees HR Human Resources Division office Tanjung Enim mining center unit PTBA. The method in this study is associative with the design of the study through the survey method by distributing questionnaires to the respondents by simple random sampling and data processed with SPSS 17.0 software. From the results of research studies can be explained that the leadership style that has a positive and significant impact on employee motivation high and low HR Division PTBA directly with the influence of (0.349) 2 = 12.18%, as well as motivation to have a positive and significant influence of high low level of employee performance PTBA Human Resources Division directly, further direct leadership style has positive and significant impact on employee performance PTBA Human Resources Division and influential leadership style indirectly through employee motivation to the Human Resources Division kenerja PTBA.
Us Dividend Policy Analyses
Authors: Wijaya Michael 
Published: October 2016

The main issue writer examines in this writing is to analyze whether or not dividend policy is a determinant to maintain stock values or firm values as a whole. It is essential that dividend policy is managed properly to enhance the satisfaction of the investors at any level of characteristics. At the end, investors are the key that determines the stock value movement. Some investors are looking for capital gain and some do care about dividend payout. Thus, the decision of dividend policy becomes crucial. It needs to understand that a firm's dividend policy may have effects on shareholder welfare. The answers can be found out by analyzing different factors of dividend policy. Taken as a whole, to see if there are other alternatives if dividend policy that can maintain or even boost up firm values. Different dividend policy has some upsides and downsides that a corporation needs to consider. One of the alternatives that is common and has become a key is stock repurchase plan.
Pola Perilaku Pembelian Produk Apparel untuk Balita oleh Millennial Moms dan Implikasinya untuk Pemasar Kids Apparel
Authors: Gunawan Annetta , Muchardie Brian Garda 
Published: October 2016

The phenomenon that recently occurred is the height of the millennial moms busy uploading pictures of their children in such a way they dressed through various social media. Accordingly, the need of the millennial moms in dressing their children up is related to the shopping patterns in kids apparel products. Buying kids products, especially apparel, not only meets the needs, but it is also the pleasure of the millennial mom. The unique characters of the millennial moms' behavior that differ from the mother’s of previous generations, make kids apparel marketers need to focus on the overall process of purchasing decisions made by the millennial moms. The purpose of this qualitative study is to explore the patterns of behavior of the millennial moms when shopping apparel products for toddlers, including the factors that influence the need awareness, information search, evaluation of alternatives, purchase behavior, and behavior post-purchase stages. Data collection method used is depth interview since the purpose of this exploratory study is to gain insight and understanding of consumers about a particular topic. The results of this study include an explanation of shopping behavior shown by the millennial moms for kids apparel products in all stages of the purchase decision process, shopping typology of millennial moms in kids apparel products, as well as the implications for marketers.
An overview of immunization practices in Pakistan
Authors: Wain Zafeer Naeem , Masood Rizwan Ali , Ali Rai Waqas , Bashir Irfan 
Published: October 2016

Effective immunization practices are invariably a big challenge for Pakistan, facing many problems and barriers to immunize children against vaccine preventable diseases. Immunization coverage in Pakistan requires up-gradation. Barriers in attaining immunization goals are lack of Parents acceptance, lack of Parents awareness and knowledge about benefits of vaccination, socioeconomic inequity and lack of security for vaccinators. The problems of vaccine procurement are its transportation, storage and administration which also contribute to errors of immunization practices. In Pakistan Expanded Program on Immunization (EPI) with the support of WHO & UNICEF has a significant impact on overcoming these barriers. Expanded Program on Immunization (EPI) is facilitating through many vaccination centers, mobile vaccination sessions and public awareness campaigns, health visitors and EPI trained vaccinators to eradicate the barriers towards poor immunization practices in Pakistan. It is concluded from this study that it is the responsibility of Government and Health Professionals to find solutions to increases vaccination rate and coverage. It is the need of hour to find ways for creating awareness among parents and motivate them to follow complete vaccination schedule for the sake of better child health.Wain et al., International Current Pharmaceutical Journal, October 2016, 5(11): 94-96http://www.icpjonline.com/documents/Vol5Issue11/01.pdf
Passage à l’âge adulte et sentiments d’injustice
Authors: Amadieu Thomas , Clément Cécile 
Published: October 2016

Cet article se propose d’étudier le lien entre les sentiments d’injustice relatifs à la société française des jeunes Français âgés de 18 à 30 ans et les injustices éventuellement vécues lors du passage à l’âge adulte. Les résultats présentés ici s’appuient sur l’analyse croisée d’une enquête par questionnaire auprès de 4 000 personnes et de 40 entretiens biographiques. Il y apparaît que l’entrée dans la vie adulte – en particulier la confrontation au monde du travail – est associée à une montée du sentiment d’injustice. Mais les sentiments d’injustice macrosociaux ne sont pas le décalque systématique des injustices vécues personnellement : ils résultent aussi d’un effort d’articulation entre des principes de justice communément partagés et une évaluation informée des inégalités observées.
Minorité et seuils d’âge légaux
Authors: Servant Patricia 
Published: October 2016

Cette synthèse présente les différents seuils d’âge légaux fixés dans différentes branches du droit français : le droit du travail, le droit civil et le droit pénal. Elle rappelle ainsi que le recours aux seuils d’âge légaux vise à la fois à protéger l’enfant qui n’a pas atteint le seuil défini légalement, tout en permettant au mineur qui l’atteint d’accéder progressivement à son statut de majeur en lui conférant de nouveaux droits.
Analysis of class 2 integrons as a marker for multidrug resistance among Gram negative bacilli
Authors: Rodríguez Cecilia , Cassini Marcelo H. , Delgado Gabriela del V. , Ramírez María S. , Centrón D ,   Argentinian Integron Study Group
Published: October 2016

AbstractClass 1 and 2 integrons are considered the paradigm of multidrug resistant (MDR) integrons. Although class 1 integrons have been found statistically associated to Enterobacteriaceae MDR isolates, this type of study has not been conducted for class 2 integrons. Escherichia coli and 3 species that were found that harbored more than 20% of class 2 integrons in clinical isolates, were selected to determine the role of intI2 as MDR marker. A total of 234 MDR/191 susceptible non-epidemiologically related isolates were analyzed. Seventy-four intI2 genes were found by PCR and sequencing. An intI2 relationship with MDR phenotypes in Acinetobacter baumannii and Enterobacter cloacae was found. No statistical association was identified with MDR E. coli and Helicobacter pylori isolates. In other words, the likelihood of finding intI2 is the same in susceptible and in MDR E. coli and H. pylori strains, suggesting a particular affinity between the mobile element Tn7 and some species. The use of intI2 as MDR marker was species-dependent, with fluctuating epidemiology at geographical and temporal gradients. The use of intI2 as MDR marker is advisable in A. baumannii, a species that can reach high frequencies of this genetic element.
Identification of Novel CD4+ T Cell Subsets in the Target Tissue of Sjögren’s Syndrome and Their Differential Regulation by the Lymphotoxin/LIGHT Signaling Axis
Authors: Haskett Scott , Ding Jian , Zhang Wei , Thai Alice , Cullen Patrick , Xu Shanqin , Petersen Britta , Kuznetsov Galina , Jandreski Luke , Hamann Stefan , Reynolds Taylor L. , Allaire Norm , Zheng Timothy S. , Mingueneau Michael 
Published: October 2016

Abstract
Despite being one of the most common rheumatologic diseases, there is still no disease-modifying drug for primary Sjögren’s syndrome (pSS). Advancing our knowledge of the target tissue has been limited by the low dimensionality of histology techniques and the small size of human salivary gland biopsies. In this study, we took advantage of a molecularly validated mouse model of pSS to characterize tissue-infiltrating CD4+ T cells and their regulation by the lymphotoxin/LIGHT signaling axis. Novel cell subsets were identified by combining highly dimensional flow and mass cytometry with transcriptomic analyses. Pharmacologic modulation of the LTβR signaling pathway was achieved by treating mice with LTβR-Ig, a therapeutic intervention currently being tested in pSS patients (Baminercept trial NCT01552681). Using these approaches, we identified two novel CD4+ T cell subsets characterized by high levels of PD1: Prdm1+ effector regulatory T cells expressing immunoregulatory factors, such as Il10, Areg, Fgl2, and Itgb8, and Il21+ effector conventional T cells expressing a pathogenic transcriptional signature. Mirroring these observations in mice, large numbers of CD4+PD1+ T cells were detected in salivary glands from Sjögren’s patients but not in normal salivary glands or kidney biopsies from lupus nephritis patients. Unexpectedly, LTβR-Ig selectively halted the recruitment of PD1− naive, but not PD1+, effector T cells to the target tissue, leaving the cells with pathogenic potential unaffected. Altogether, this study revealed new cellular players in pSS pathogenesis, their transcriptional signatures, and differential dependency on the lymphotoxin/LIGHT signaling axis that help to interpret the negative results of the Baminercept trial and will guide future therapeutic interventions.
Amiodarone-Induced Pulmonary Toxicity – A Frequently Missed Complication
Authors: Sweidan Alexander J. , Singh Navneet K. , Dang Natasha , Lam Vinh , Datta Jyoti 
Published: October 2016

Introduction Amiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT). Several pulmonary diseases can manifest including interstitial pneumonitis, organizing pneumonia, acute respiratory distress syndrome, diffuse alveolar hemorrhage, pulmonary nodules or masses, and pleural effusion. Incidence of APT varies from 5–15% and is correlated to dosage, age of the patient, and preexisting lung disease. Description A 56-year-old male with a past medical history of coronary artery disease and chronic obstructive pulmonary disease was admitted for a coronary artery bypass graft. Post-operatively, the patient was admitted to the ICU for ventilator management and continued to receive his home dose of amiodarone 400 mg orally twice daily, which he had been taking for the past 3 months. The patient was found to be hypoxemic with a PaO2 52 mmHg and bilateral infiltrates on chest x-ray. Patient also complained of new onset dyspnea. Physical exam found bilateral rhonchi with bibasilar crackles and subcutaneous emphysema along the left anterior chest wall. Daily chest x-rays showed worsening of bilateral interstitial infiltrates and pleural effusions. A chest high-resolution computed tomography on post-operative day 3 showed extensive and severe bilateral ground glass opacities. APT was suspected and amiodarone was discontinued. A course of oral prednisone without antibiotics was initiated, and after one week of treatment the chest film cleared, the PaO2 value normalized and dyspnea resolved. Discussion APT occurs via cytotoxic T cells and indirectly by immunological reaction. Typically the lungs manifest a diffuse interstitial pneumonitis with varying degrees of fibrosis. Infiltrates with a ‘ground-glass’ appearance appreciated on HRCT are more definitive than chest x-ray. Pulmonary nodules can be seen, frequently in the upper lobes. These are postulated to be accumulations of amiodarone in areas of previous inflammation. Those undergoing major cardiothoracic surgery are known to be predisposed to APT. Some elements require consideration: a baseline pulmonary function test (PFT) did not exist prior. APT would manifest a restrictive pattern of PFTs. In APT diffusing capacity (DLCO) is generally >20 percent from baseline. A DLCO was not done in this patient. Therefore, not every type of interstitial lung disease could be ruled out. Key features support a clinical diagnosis: (1) new dyspnea, (2) exclusion of lung infection, (3) exclusion of heart failure, (4) new radiographic features, (5) improvement with withdrawal of amiodarone. Our case illustrates consideration of APT in patients who have extensive use of amiodarone and new onset dyspnea.
The Implementation of Problem-Based Learning (PBL) in a Year 9 Mathematics Classroom: A Study in Brunei Darussalam
Authors: Botty Haji Mohammad Redzuan Haji , Shahrill Masitah , Jaidin Jainatul Halida , Li Hui-Chuan , Chong Maureen Siew Fang 
Published: October 2016

<p>Problem-Based Learning (PBL) is a constructivist, student-centered instructional strategy in which students work collaboratively to solve problems and reflect on their learning experiences to advance or gain new knowledge. PBL was originally developed in medical school programs at the McMaster University in Canada in the 1960s. Since then, much research has highlighted the benefits of PBL for developing students’ mathematical knowledge in more flexible and novel ways than traditional teacher-centered teaching approaches. However, there has been a lack of studies examining how PBL can be applied to mathematics teaching and learning, since studies that have investigated the implementation of PBL outside a medical context are sparse in Brunei Darussalam. Therefore, in this study, we attempted to fill this research gap by exploring the implementation process of PBL in a Year 9 mathematics classroom and its possible impact on students’ learning in mathematics in the context of Brunei Darussalam. The participants of the study consisted of 17 Year 9 students (ages 14-15) from a secondary school in Brunei Darussalam The findings from our study showed that the implementation of PBL helped motivate the students to collaboratively work as a group and learn from their peers and therefore, gradually reduced their dependence on the teacher during the course of the intervention. The results from the students’ performances on the pre-test and the post-test also provided evidence to show that the implementation of PBL could have a positive impact on the students’ learning in mathematics. Directions for future mathematical PBL implementation are also discussed and offered. </p>
DasR positively controls monensin production at two-level regulation in Streptomyces cinnamonensis
Authors: Zhang Yue , Lin Chun-Yan , Li Xiao-Mei , Tang Zheng-Kun , Qiao Jianjun , Zhao Guang-Rong 
Published: October 2016

Abstract
The polyether ionophore antibiotic monensin is produced by Streptomyces cinnamonensis and is used as a coccidiostat for chickens and growth-promoting agent for cattle. Monensin biosynthetic gene cluster has been cloned and partially characterized. The GntR-family transcription factor DasR regulates antibiotic production and morphological development in Streptomyces coelicolor and Saccharopolyspora erythraea. In this study, we identified and characterized the two-level regulatory cascade of DasR to monensin production in S. cinnamonensis. Forward and reverse genetics by overexpression and antisense RNA silence of dasR revealed that DasR positively controls monensin production under nutrient-rich condition. Electrophoresis mobility shift assay (EMSA) showed that DasR protein specifically binds to the promoter regions of both pathway-specific regulatory gene monRII and biosynthetic genes monAIX, monE and monT. Semi-quantitative RT-PCR further confirmed that DasR upregulates the transcriptional levels of these genes during monensin fermentation. Subsequently, co-overexpressed dasR with pathway-specific regulatory genes monRI, monRII or monH greatly improved monensin production.
Genetic Counselor Workforce Issues: a Survey of Genetic Counselors Licensed in the State of Indiana
Authors: Cohen Stephanie A. , Tucker Megan E. , Delk Paula 
Published: October 2016

AbstractThe aims of this study were to document movement of genetic counselors (GCs) out of clinical positions and identify factors that might help employers attract and retain clinical GCs. A confidential on‐line survey of GCs ever licensed in the state of Indiana was conducted. Of the 46 respondents, most provide direct patient care (69.6 %), have worked in their current position for 5 years or less (72.1 %), and are experienced genetic counselors, having graduated between 6 and 15 years ago (43.5 %). One‐third (32.6 %) reported thinking about leaving their current position at least monthly. GCs were more likely to think about leaving their current position when they provided direct patient care (p = 0.04) and worked in a hospital/clinic setting (p = 0.01). Among the 18 respondents that changed jobs in the past two years, 55.6 % currently work in a laboratory/industry setting and 44.4 % provide direct patient care, compared to 8 % of those in a stable position (N = 25) who work in a laboratory/industry setting (p < 0.01) and 88 % who provide direct patient care (p < 0.01). Genetic counselors who have changed jobs within the past 2 years were more satisfied with the possibility for advancement (p = 0.01), the recognition for work they do (p = 0.03) and feeling value from the organization (p = 0.04) in their current positions than those who have not changed jobs. Salary and flexibility were most often reported as reasons for changing jobs. This is the first documentation of the movement of GCs out of clinical roles into industry positions. This changing landscape may impact the access to clinical services and the training of genetic counseling students. This data will provide employers with data to help attract and retain GCs in clinical roles.
How inferred contagion biases dispositional judgments of others
Authors: Hingston Sean T. , McManus Justin F. , Noseworthy Theodore J. 
Published: October 2016

AbstractDrawing on recent evidence suggesting that beliefs about contagion underlie the market for celebrity‐contaminated objects, the current work investigates how people can make biased dispositional judgments about consumers who own such objects. Results from four experiments indicate that when a consumer comes in contact with a celebrity‐contaminated object and behaves in a manner that is inconsistent with the traits associated with that celebrity, people tend to make more extreme judgments of them. For instance, if the celebrity excels at a particular task, but the target who has come into contact with the celebrity‐contaminated object performs poorly, people reflect more harshly on the target. This occurs because observers implicitly expect that a consumer will behave in a way that is consistent with the traits associated with the source of contamination. Consistent with the law of contagion, these expectations only emerge when contact occurs. Our findings suggest that owning celebrity‐contaminated objects signals information about how one might behave in the future, which consequently has social implications for consumers who own such objects.
Modificación simplificada de la técnica de Zancolli para la corrección de la garra cubital
Authors: González R. , Hernández D. , Castro E. , Egüez G. 
Published: October 2016

Objetivos: Estudiar los resultados obtenidos con la técnica de Chevallard, versión simplificada de la técnica de Zancolli, para corregir la deformidad de la mano en garra secundaria a una parálisis cubital.Material y método: Estudio retrospectivo (enero 2006-diciembre 2013) de 16 pacientes (16 manos) que fueron intervenidos quirúrgicamente por deformidad en garra de la mano secundaria a parálisis del nervio cubital. Siguiendo los criterios de Brand, los pacientes fueron evaluados a las 6 semanas, 3 meses, 6 meses y al año.Resultados: Los resultados al año de la intervención fueron: excelentes en el 18,75% (3 pacientes); buenos en el 75% (12 pacientes) y malos en el 6,25% (un paciente). Este último requirió una nueva intervención para solucionar la recidiva de la garra.Conclusión: La técnica simplificada de Zancolli, o técnica de Chevallard, permite corregir fácilmente la deformidad de la mano en garra secundaria a una parálisis cubital, no hipotecando una ulterior intervención en el caso de recidiva.
Simple strategy for fabricating a Prussian blue/chitosan/carbon nanotube composite and its application for the sensitive determination of hydrogen peroxide
Authors: Wang Cong , Zhang Keying , Zhang Na , Zhang Li , Wang Hongyan , Xu Jigui , Shi Hongwei , Zhuo Xin , Qin Miao , Wu Xingxing 
Published: October 2016

A simple strategy was presented for fabricating a Prussian blue (PB)/chitosan (CHIT)/multi‐walled carbon nanotube (MWCNT) composite. A simple chemical reaction was used to form PB nanoparticles on the surface of an electrode modified with CHIT–MWCNTs. Scanning electron microscopy and Fourier transform infrared spectroscopy were used to characterize the composite. PB–CHIT–MWCNTs were employed to construct an electrochemical hydrogen peroxide (HP) sensor. Tests showed that the sensor exhibited excellent electrocatalytic ability toward the reduction of HP. The amperometric response was linear with concentrations of HP in the range of 1.0 µM–0.5 mM, with a detection limit of 0.1 μM (S/N = 3). In addition, this sensor showed excellent selectivity, reproducibility, and stability, and it was satisfactorily applied for HP detection in real samples.
Controlling uncertainty in aptamer selection
Authors: Spill Fabian , Weinstein Zohar B. , Irani Shemirani Atena , Ho Nga , Desai Darash , Zaman Muhammad H. 
Published: October 2016

Significance
Oligonucleotide aptamers have increasing applications as a class of molecules that bind with high affinity and specificity to a target. Aptamers are typically selected from a large pool of random candidate nucleic acid libraries through competition for the target. Using a stochastic hybrid model, we are able to study the combined impact of important evolutionary success factors such as competition, randomness, and changes in the environment. Whereas the environment may be tuned with experimental parameters such as target concentration, competition varies with differences in the initial distribution of aptamer–target binding affinities, and random events can eliminate even the ligands with the highest affinity.