bluuebunny/crossref_metadata_2025_split huggingface dataset:
A framework for evaluating tool support for co-evolution of modeling languages, tools and models
Authors: Tolvanen Juha-Pekka , Kelly Steven , Di Rocco Juri , Pierantonio Alfonso , Tinella Giordano 
Published: October 2024

AbstractWe present a framework for evaluating language workbenches’ capabilities for co-evolution of graphical modeling languages, modeling tools and models. As with programming, maintenance tasks such as language refinement and enhancement typically account for more work than the initial development phase. Modeling languages have the added challenge of keeping tools and existing models in step with the evolving language. As domain-specific modeling languages and tools have started to be used widely, thanks to reports of significant productivity improvements, some language workbench users have indeed reported problems with co-evolution of tools and models. Our tool-agnostic evaluation framework aims to cover changes across the whole language definition: the abstract syntax, concrete syntax, and constraints. Change impact is assessed for knock-on effects within the language definition, the modeling tools, semantics via generators, and existing models. We demonstrate the viability of the framework by evaluating MetaEdit+, EMF/Sirius and Jjodel, providing a detailed evaluation process for others to repeat with their tools. The results of the evaluation show differences among the tools: from editors not opening correctly or at all, through highlighting of items requiring manual intervention, to fully automatic updates of languages, models and editors. We call for industry to evaluate their tool choices with the framework, tool developers to extend their tool support for co-evolution, and researchers to refine the evaluation framework and evaluations presented.
Blind prediction and post-experimental analysis of RC core wall’s cyclic flexural response using MVLEM-FD
Authors: Janevski Antonio , Isakovic Tatjana 
Published: October 2024

AbstractBlind prediction and post-experimental studies of the flexural cyclic response of a U-shaped core wall, tested at UCLouvain, Belgium, are presented. The tested specimen (referred to as UW1) was modelled using a relatively simple 3D force–displacement-based version of the beam–column multiple-vertical-line-element (MVLEM-FD), developed at the University of Ljubljana (UL), using standard element parameters. The blind prediction accurately identified critical failure points within the specimen. However, the predicted type of failure, attributed to the rupture of longitudinal bars in the boundary region of flanges was somewhat different from that observed in the experiment. These bars were indeed ruptured, but their rupture was preceded by their buckling and the spalling of the surrounding concrete core. Moreover, the predicted force–displacement hysteretic loop exhibited a slight shift compared to experimental observations. Post-experimental studies revealed that this discrepancy was primarily due to the modelling of the loading at the top of the wall rather than the modelling of the wall itself. Specifically, an additional bending moment induced by the eccentricity of the vertical load applied using three actuators, which was overlooked in the blind prediction. Upon correcting the loading, the agreement between the numerical studies and experiment was considerably improved in terms of both the global and local response quantities. Additionally, minor improvements in modelling the boundary regions of the wall’s flanges, considering the relatively large unconfined concrete cover, were introduced, leading to enhanced estimations of near-collapse response.
Identifying Important Pairwise Logratios in Compositional Data with Sparse Principal Component Analysis
Authors: Nesrstová Viktorie , Wilms Ines , Hron Karel , Filzmoser Peter 
Published: October 2024

Abstract
Compositional data are characterized by the fact that their elemental information is contained in simple pairwise logratios of the parts that constitute the composition. While pairwise logratios are typically easy to interpret, the number of possible pairs to consider quickly becomes too large even for medium-sized compositions, which may hinder interpretability in further multivariate analysis. Sparse methods can therefore be useful for identifying a few important pairwise logratios (and parts contained in them) from the total candidate set. To this end, we propose a procedure based on the construction of all possible pairwise logratios and employ sparse principal component analysis to identify important pairwise logratios. The performance of the procedure is demonstrated with both simulated and real-world data. In our empirical analysis, we propose three visual tools showing (i) the balance between sparsity and explained variability, (ii) the stability of the pairwise logratios, and (iii) the importance of the original compositional parts to aid practitioners in their model interpretation.
Advanced imaging reveals enhanced malignancy in glioblastomas involving the subventricular zone: evidence of increased infiltrative growth and perfusion
Authors: Griessmair Michael , Schramm Severin , Ziegenfeuter Julian , Canisius Julian , Jung Kirsten , Delbridge Claire , Schmidt-Graf Friederike , Mitsdoerffer Meike , Zimmer Claus , Meyer Bernhard , Metz Marie-Christin , Wiestler Benedikt 
Published: October 2024

Abstract
Background
Glioblastoma’s infiltrative growth and heterogeneity are influenced by neural, molecular, genetic, and immunological factors, with the precise origin of these tumors remaining elusive. Neurogenic zones might serve as the tumor stem cells’ nest, with tumors in contact with these zones exhibiting worse outcomes and more aggressive growth patterns. This study aimed to determine if these characteristics are reflected in advanced imaging, specifically diffusion and perfusion data.

Methods
In this monocentric retrospective study, 137 glioblastoma therapy-naive patients (IDH-wildtype, grade 4) with advanced preoperative MRI, including perfusion and diffusion imaging, were analyzed. Tumors and neurogenic zones were automatically segmented. Advanced imaging metrics, including cerebral blood volume (CBV) from perfusion imaging, tissue volume mask (TVM), and free water corrected fractional anisotropy (FA-FWE) from diffusion imaging, were extracted.

Results
SVZ infiltration positively correlated with CBV, indicating higher perfusion in tumors. Significant CBV differences were noted between high and low SVZ infiltration cases at specific percentiles. Negative correlation was observed with TVM and positive correlation with FA-FWE, suggesting more infiltrative tumor growth. Significant differences in TVM and FA-FWE values were found between high and low SVZ infiltration cases.

Discussion
Glioblastomas with SVZ infiltration exhibit distinct imaging characteristics, including higher perfusion and lower cell density per voxel, indicating a more infiltrative growth and higher vascularization. Stem cell-like characteristics in SVZ-infiltrating cells could explain the increased infiltration and aggressive behavior. Understanding these imaging and biological correlations could enhance the understanding of glioblastoma evolution.
Joining attention to see differently
Authors: Ianniello Antonio 
Published: October 2024

AbstractStarting from an embodied approach to the study of the mind, and drawing on Alva Noe’s proposition that the work of art allows us to move from seeing to seeing differently, I propose that some art performances emphasize the fact that the community bears this passage, and particularly highlight the importance of joint attention in this process. To develop my argument, I will consider what art historian Claire Bishop has termed the “gray zone,” which has emerged in the last 15 years or so as a result of the entry of the performing arts, normally housed in theatrical spaces, into museums, usually used for the display of immobile objects. This shift involves the breaking of certain spectatorial constraints, such as sitting isolated in the darkness of a room typical of traditional theater, and puts the subject in a position to engage in processes of joint attention. I will focus in particular on the analysis of the performance Faust, emblematic of the gray zone that I propose paradoxically emphasizes the potentially transformative power of “we”.
Automatische Insulindosierung (AID)
Authors: Ware Julia 
Published: October 2024

ZusammenfassungMit der Kommerzialisierung und klinischen Verfügbarkeit der automatischen Insulindosierung (AID) brach ein neues Zeitalter in der Behandlung des Typ-1-Diabetes an. Robuste Forschungsergebnisse randomisierter Langzeitstudien ergaben: Die AID-Therapie verbessert die Stoffwechsellage in allen pädiatrischen Altersgruppen, ohne dass höhere akute Komplikationen oder Hypoglykämieraten auftreten. Daten des realen Lebens aus prospektiven Beobachtungsstudien und retrospektive Clouddaten der Hersteller bestätigen diese Behandlungserfolge. Auch bei Manifestation sind AID-Systeme sicher einsetzbar und bringen gegenüber Standardtherapien langfristig Vorteile für Kinder und Jugendliche mit neu diagnostiziertem Typ-1-Diabetes. Langzeitstudien mit Daten des realen Lebens gibt es noch nicht. In Zukunft sollten Registerdaten diesbezüglich ausgewertet werden, um systemübergreifend die Beständigkeit der glykämischen Outcomes zu erschließen. Ein vollautomatisches AID-System, bei dem die Notwendigkeit der manuellen Abgabe von Insulinboli zu den Mahlzeiten entfällt, bleibt das ultimative Ziel der AID-Forschung, ist aber bislang nicht erhältlich und bei Kindern und Jugendlichen wenig erforscht.
Automatische Insulindosierung (AID) bei Kindern und Jugendlichen mit Typ-1-Diabetes
Authors: Tauschmann Martin 
Published: October 2024

ZusammenfassungIn den letzten 2 Jahrzehnten hat sich das Management von Typ-1-Diabetes (T1D) durch technologische Fortschritte erheblich verändert. Insulinpumpen und kontinuierliche Glukosemesssysteme (CGM) haben die traditionelle Basis-Bolus-Therapie und kapillare Blutzuckermessung ersetzt und sich als effektive Therapien etabliert, insbesondere im pädiatrischen Bereich.Automatisierte Insulinabgabesysteme (AID) kombinieren kontinuierliche Glukosemessung (CGM) mit Insulinpumpen im Sinne einer automatischen glukoseresponsiven Anpassung der Insulindosis. Die Nutzung von AID-Systemen nimmt rasch zu und wird von internationalen Gesellschaften in der Therapie von Kindern und Jugendlichen mit T1D empfohlen, idealerweise auch möglichst rasch nach der Diagnosestellung. In vielen Ländern entwickelten sich AID-Systeme auf diese Weise bereits zum Goldstandard in der Behandlung dieser Altersgruppen.Seit der Einführung des ersten kommerziellen AID-Systems wurden weitere Systeme entwickelt und zugelassen. Die AID-Technologie erwies sich als effektiv in der Verbesserung der glykämischen Kontrolle und zeigte auch vielversprechende Ergebnisse bei Kleinkindern, obwohl die Verfügbarkeit der Systeme in dieser Altersgruppe noch begrenzt ist.
Adverse Childhood Experiences, Quality of Life and the Mediating Roles of Self-Efficacy and Self-Directedness in Youth Residential Care Leavers
Authors: Leiting Milou , Beck Katharina , Bürgin David , Fegert Jörg M. , Jenkel Nils , Boonmann Cyril , Schmeck Klaus , Grob Alexander , Schmid Marc 
Published: October 2024

Abstract
Purpose
Young people in youth residential care report high rates of adverse childhood experiences (ACEs), e.g., abuse and neglect in their families. Various studies show ACEs to impair social participation and mental health, whereas less is known about how ACEs are associated with quality of life (QoL). The aim of the current study is to (1) evaluate the association between ACEs and psychological, physical, social, and environmental QoL in young adult care leavers, and (2) to examine how self-efficacy and self-directedness mediate this association.

Methods
179 formerly out-of-home placed young adults (Mage = 26.5, 33.4% women, response rate = 30.3%) were queried at baseline with the Junior Temperament and Character Inventory Revised (JTCI 12-18-R) and at a 10-year follow-up with the Maltreatment and Abuse Chronology of Exposure (MACE) scale, the General Self-Efficacy Scale (GSE) and the World Health Organization Quality-of-Life Questionnaire (WHOQoL-BREF).

Results
Prevalence rates for ACEs were high, with 87.2% of participants experiencing at least one type of ACE. Cumulative ACEs were associated with lower QoL in all four domains. Self-efficacy (β = -0.111, [-0.187, -0.044]) and self-directedness (β = -0.052, [-0.123, -0.004]) partially mediated the association between severity of ACEs and overall QoL.

Conclusions
ACEs increase the risk for a lower QoL of young adult care leavers. Results underline the importance of prevention and early intervention efforts for troubled young people and their families, as well as the importance of pedagogical work during residential care. Additional to research on functional outcomes, studies investigating well-being and quality of life in this at-risk populations are needed.
Trends in brain MRI and CP association using deep learning
Authors: Hassan Muhammad , Lin Jieqiong , Fateh Ahmad Ameen , Zhuang Yijiang , Lin Guisen , Khan Dawar , Mohammed Adam A. Q. , Zeng Hongwu 
Published: October 2024

AbstractCerebral palsy (CP) is a neurological disorder that dissipates body posture and impairs motor functions. It may lead to an intellectual disability and affect the quality of life. Early intervention is critical and challenging due to the uncooperative body movements of children, potential infant recovery, a lack of a single vision modality, and no specific contrast or slice-range selection and association. Early and timely CP identification and vulnerable brain MRI scan associations facilitate medications, supportive care, physical therapy, rehabilitation, and surgical interventions to alleviate symptoms and improve motor functions. The literature studies are limited in selecting appropriate contrast and utilizing contrastive coupling in CP investigation. After numerous experiments, we introduce deep learning models, namely SSeq-DL and SMS-DL, correspondingly trained on single-sequence and multiple brain MRIs. The introduced models are tailored with specialized attention mechanisms to learn susceptible brain trends associated with CP along the MRI slices, specialized parallel computing, and fusions at distinct network layer positions to significantly identify CP. The study successfully experimented with the appropriateness of single and coupled MRI scans, highlighting sensitive slices along the depth, model robustness, fusion of contrastive details at distinct levels, and capturing vulnerabilities. The findings of the SSeq-DL and SMSeq-DL models report lesion-vulnerable regions and covered slices trending in age range to assist radiologists in early rehabilitation.
Partnership Histories Shape the Grandparenting Happiness Bonus
Authors: Rotkirch Anna , Hägglund Anna , Tanskanen Antti O. , Danielsbacka Mirkka 
Published: October 2024

AbstractEvolutionary theory predicts that returns on investments in family relations will vary by sex and life stage and that there can be a trade-off between mating and (grand)parenting. Family sociology has shown that whereas couple relations are central to happiness in older age, the effects of grandparenting are more mixed and context dependent. Here, we merge these two perspectives and study how partnership histories over the life course relate to happiness among Europeans aged 50+ and whether grandparental investment moderates these associations. Of particular interest is whether there are signs of trade-offs, cumulative benefits, or compensatory benefits between the type of couple relations and grandparenting in postreproductive age.We employed the Survey of Health, Ageing and Retirement in Europe with data from 26 European countries and Israel for the years 2004–2020. The analyses distinguish between respondents who are in their first, second, or third union through marriage or cohabitation; are divorced; are widowed; are living apart from a partner; or are single. We investigated how quality of life and life satisfaction are associated with these seven types of partnership histories and whether the associations are moderated by grandparental status and provision of grandchild care.Europeans with a partner, and especially those in their first union, were happier than those in other partnership groups, and grandparents were happier than individuals without grandchildren. Grandparental investment was associated with being happier in most partnership groups. The “grandparenting bonus” was greatest among unpartnered respondents, suggesting a compensatory effect. We found no signs of a cumulative effect, nor of costs to happiness from grandchild care.Our results illustrate how reproductive strategies over the life course shape happiness returns to grandparenting. Being a grandparent and, especially, providing care for grandchildren may compensate for the lower happiness associated with the loss or lack of a partner.
Computational Analysis of Cold Spraying Polymer-Coated Metallic Particles on Fiber-Reinforced Polymer Substrates
Authors: Mennie Nicholas B. , Singh Nand K. , Nault Isaac , Haas Francis M. , Koohbor Behrad 
Published: October 2024

AbstractFiber-reinforced polymer composites are prominent structural components in various industries such as aerospace, automotive, and wind energy. These materials are considered due to their high strength-to-weight ratio and relative ease of fabrication. However, fiber composites possess low electrical and thermal conductivities and are prone to impact-induced damage. Metallization of fiber-reinforced polymer composites has become an area of interest as a means to prevent abrasive and corrosive damage while also improving other physical properties including thermal and electrical conductivity. The possibility of using cold spray as a novel composite metallization approach has been investigated in this work. The significance of cold spray for metallization is due to relatively low process temperatures which effectively protect the underlaid substrate from potential temperature degradation. As a practical approach to further reduce the possibility of cold spray-induced damage, the present study explores the impact and failure mechanics of metal particles coated with a thin polymeric shell, hence the term polymer-coated metal particle. The thorough model-based analyses presented herein indicate that the so-called polymer-coated metal particles can be cold spray deposited without imposing significant damage to the composite substrate mainly due to the ‘cushioning’ effect of the thin polymer shell. The results discussed here also provide guidelines for the surface metallization of high-performance fiber-reinforced thermoplastic composites in practice.
Long-Term Weight Loss and Attendance Outcomes Following Metabolic and Bariatric Surgery: An Evaluation of The Cleveland Clinic Behavioral Rating System
Authors: Jacobs Anne , Vermeer Karlijn , Slok Anna N. , Janssen Ignace M. C. , Tollenaar Rob A. E. M. , Monpellier Valerie M. 
Published: October 2024

Abstract
Introduction
Interdisciplinary guidelines recommend preoperative psychological evaluation before metabolic and bariatric surgery (MBS). The Cleveland Clinic Behavioral Rating System (CCBRS) has been developed to evaluate the psychological state of individuals undergoing MBS. However, its predictive value concerning long-term weight loss and follow-up attendance has not been extensively studied. This study aims to assess the predictive value of the CCBRS regarding weight loss and follow-up attendance up to 5 years after MBS.

Methods
In this cohort study (n = 1236), psychologists administered the CCBRS to each patient prior to MBS in addition to the standard psychosocial-behavioral screening. The CCBRS consists of nine psychological domains and is scored on a five-point Likert scale, from “poor” to “excellent.” Linear mixed models and ordinal regression analysis were used to analyze the percentage total weight loss over time and follow-up attendance up to 5 years after surgery.

Results
A total of 1086 patients underwent subsequent MBS. Significant differences in weight loss and follow-up attendance were observed between some CCBRS groups compared to the reference group “excellent.” However, these differences were not consistent across all groups within any given domain.

Conclusion
In this cohort, the predictive value of the CCBRS for weight loss and follow-up attendance up to 5 years after MBS was limited. It is important to consider certain limitations, such as considerable loss to follow-up. Nevertheless, the CCBRS remains valuable for structured psychological assessments by helping to identify patients’ strengths and areas needing improvement.

Graphical Abstract
DNA barcoding, pollen and seed characteristics for documentation of four monocot Mediterranean endemic plant species in Egypt
Authors: El-Khalafy Mohamed M. , El-Kholy Aziza S. , Ahmed Dalia A. , Al-Sodany Yassin M. , Haroun Soliman A. , Shaltout Kamal H. , Salim Mohamed A. 
Published: October 2024

AbstractEndemic taxa are critical constituents in the flora of most parts of the world. Recently, most of these taxa have become exposed to extinction. This study aims to increase understanding of four monocot Mediterranean threatened endemic taxa in Egypt (Allium mareoticum Bornm. & Gauba, Bromus aegyptiacus Tausch, Muscari salah-eidii (Täckh. & Boulos) Hosni, Pancratium arabicum Sickenb.) by description of their pollen and seed and authentication of DNA barcoding using rbcL and matK genes. Twenty field visits were conducted from March 2017 till April 2023 including different localities through Mediterranean area for covering the presence of these species. Characterization of pollen grains and seeds were examined using a light (LM) and scanning electron microscopes (SEM). DNA barcoding was carried out for documentation of the four species. Maturase K (matK) and ribulose-bisphosphate carboxylase (rbcL) were used as primers for PCR amplification and gene sequencing. The two genes were successful in identifying Allium mareoticum, Bromus aegyptiacus, and Muscari salah-eidii at the genus level and Pancratium arabicum at both species and genus levels for rbcL marker, and the genus level for matK marker. This study is considered a leading study for new barcodes of (A) mareoticum, (B) aegyptiacus, and M. salah-eidii which were initially made available to the NCBI.