bluuebunny/crossref_metadata_2025_split huggingface dataset:
Definition of a coordinate system for multi-modal images of the temporal bone and inner ear
Authors: Copson Bridget , Wijewickrema Sudanthi , Slinger Christopher , Youssef Daniel , Gerard Jean-Marc , O’Leary Stephen 
Published: October 2024

Purpose
The position and orientation of the head is maintained to be relatively similar during the CT / MR imaging process. However, the position / orientation dissimilarities present in the resulting images between patients, or between different scans of the same patient, do not allow for direct comparison of the images themselves or features / metrics extracted from them. This paper introduces a method of defining a coordinate system which is consistent between patients and modalities (CT and MR) for images of the temporal bone, using easily identifiable landmarks within the semicircular canals.

Methods
Cone Beam CT and high resolution MRI (T2) images of the temporal bone from 20 patients with no cochlear or temporal bone pathology in either modality were obtained. Four landmarks within the semicircular canals were defined that can be identified in both modalities. A coordinate system was defined using these landmarks. Reproducibility of landmark selection was assessed using intra- and inter-rater reliability (for three expert raters and two repeats of the landmark selection). Accuracy of the coordinate system was determined by comparing the coordinates of two additional landmarks in CT and MR images after their conversion to the proposed coordinate system.

Results
Intraclass Correlation Coefficients at a 95% level of confidence showed significant agreement within and between raters as well as between modalities. The differences between selections, raters, and modalities (as measured using mean, standard deviation, and maximum) were low and acceptable for clinical applications.

Conclusion
The proposed coordinate system is suited for use in images of the temporal bone and inner ear. Its multi-modal nature enables the coordinate system to be used in tasks such as image co-registration.
First-line Nurse Managerial Competence and Its Influencing Factors in Public Jordanian Hospitals
Authors: Iblasi Abdulkareem S. , Makahleh Samer , Aungsuroch Yupin , Gunawan Joko , Juanamasta I Gede 
Published: October 2024

Background: First-line Nurse Managers (FLNMs) occupy pivotal positions within healthcare systems, responsible for various administrative and caregiving functions. While FLNMs are integral to efficient healthcare services, their competencies and the factors influencing them still need to be explored in this region. In light of the need for more research on FLNM competencies in Jordan, this study is paramount for advancing healthcare in the country.Purpose: This study aimed to analyze FLNM competencies and its influencing factors within the unique context of Jordan's healthcare system.Methods: As a cross-sectional study, the research leveraged online platforms to disseminate the 130 FLNM to three Jordan's central region public hospitals with random sampling method. FLNM questionnaire was used to collect the data. Univariate analysis comprised numerical data (M, median, mode, SD) and categorical data (percentage and proportion). Pearson, independent t test and multiple linear regression were used to analyzed the data.Results: Based on responses from 130 FLNMs, the study's results demonstrated their average age to be approximately 37.8 years, with a significant proportion holding master's degrees, indicating a highly educated cohort. Notably, many FLNMs were charge nurses, reflecting their extensive experience and commitment to enhancing their leadership competencies. The study found no significant correlation between age and FLNM competencies, suggesting that competence is not solely contingent upon years of experience or age (p>0.05). The research revealed the highest to the lowest significance in FLNM performance were leadership training (b=21.15, 95%CI=7.70-34.60, p=0.002), gender-based disparities (b=16.50, 95%CI=4.41-28.58, p=0.008) and social status (b=7.86, 95%CI=1.13-14.60, p=0.02), respectively. Conclusion: This gender difference may be influenced by cultural or contextual factors unique to the Jordanian healthcare landscape, warranting further exploration. The research highlights the need for tailored training and support programs to improve the competencies of FLNMs in Jordan's healthcare system, highlighting gender-based differences and the need for personalized healthcare management strategies to improve healthcare quality.
Promoting a sense of belonging in university online learning: How and why initial teacher education students experience an increased sense of belonging
Authors: Adlington Rachael , O'Neill Kristy , Volpe Catherine Rita , Harrington Ingrid 
Published: October 2024

Despite evidence of practices that support online students in university learning, promoting engagement and building a student sense of belonging continue to be a challenge. To enhance student engagement, a suite of evidence-based learning design strategies was incorporated across online units of study in initial teacher education programmes at a regional Australian university. To determine the impact of these strategies or elements, students were surveyed regarding their perspectives on how the elements had positively impacted their sense of belonging within the online university community. The systemic functional linguistics Appraisal framework was used to analyse qualitative survey data, which reported students experienced an increased sense of belonging expressed as positive judgements of their own mental capacities. Students also expressed feeling cared for, valued and supported by academics and experienced enjoyment in their learning and reduced levels of stress. All elements were positively evaluated; however, unit coordinator behaviour, especially social capacity, was unexpectedly important in increasing student sense of belonging. Whilst ongoing incorporation of design elements to enhance engagement is important, the behaviours of unit coordinators actioned through these elements were paramount in promoting student belonging.

Implications for practice or policy:

Increasing levels of student belonging may be improved by including learning experiences that promote feelings of success and relationships with others.
Unit coordinators can enhance online student belonging by using online learning design elements to demonstrate approachability, understanding, supportiveness, availability, presence, care and patience.
Universities should consider adopting organisation-wide initiatives that promote consistent and visible learning design features and staff presence, with the aim of addressing attrition and retention challenges.
Mitigating product placement effects induced by repeated exposure: Testing the effects of existing textual disclosures in children’s movies on disclosure awareness
Authors: Spielvogel Ines , Binder Alice , Matthes Jörg 
Published: October 2024

Abstract
In certain cases, children can react strongly in favor of product placements inserted in movies. Scholars therefore argue that existing disclosures might be one strategy in protecting children from any negative effects. However, disclosure research indicates that viewers should both notice disclosures and, in cases of textual cues, read them. We conducted an experiment with 139 children (Mage = 8.46; SD = 1.12; girls = 53.2 %) and tested the influence of textual disclosure format on disclosure awareness as well as brand-related effects. When comparing with no disclosure, results showed that exposure to an existing textual disclosure positively affects disclosure awareness while exposure to an expanded version of it (i.e., by using more textual elements) did not. Further analyses revealed that prior movie exposure positively affected brand evaluation. However, disclosure awareness reversed this effect. We conclude that children appear to be socialized with the existing textual disclosure and that disclosure awareness might be of importance in shielding children against persuasive influence.
Race, Market Size, Segregation and Subsequent Opportunities for Former NFL Head Coaches
Authors: Foreman Jeremy J. , Turick Robert M. , Williams Dylan P. , Skinner Tyler L. 
Published: October 2024

Abstract
This study examines subsequent head coach opportunities for former National Football League (NFL) head coaches. Under a subsequent CEO career framework, survival analysis is used to examine the effects of race and market characteristics on subsequent NFL head coach opportunities for former head coaches. Observations of former head coaches who neither ended their coaching careers nor possess head coach positions in the observed seasons are used (n = 1,132). Black former NFL head coaches are less likely to secure subsequent NFL head coaching opportunities if their most recent coaching position was in a large media market. However, both Black and non-Black former head coaches who most recently coached in highly segregated metropolitan areas experienced higher likelihoods of securing subsequent head coaching opportunities. This segregated market effect is even stronger for Black former head coaches. The NFL can utilize this information in policy formation decisions regarding hiring policies and practices. Teams and their lead executives can also use this information to identify any personal biases that may arise within the head coach labor market. Coaches may use the information to best position themselves for subsequent career opportunities.
FTX promotes esophageal cancer progression and desensitizes esophageal cancer cells to ionizing radiation by microRNA-99a/b-3p/WEE1/ERCC1 axis
Authors: Xu Yangjie , Huang Chaoming , Mao Zijuan , Fu Yuanyuan , Hao Qiongyu , Fei Zhenghua 
Published: October 2024

Abstract

Objectives
This study was conducted to uncover the underlying cellular and molecular mechanisms of five prime to Xist (FTX) dysregulation in esophageal cancer (EC).

Methods
The gene expression in tumor tissues was detected using western blot, immunohistochemistry, and quantitative real-time polymerase chain reaction (qPCR). The dual-luciferase reporter and RNA FISH assays confirmed the interaction between miRNA and target genes. Mouse models for Xenograft and lung metastasis were used to assess EC cell tumorigenesis and metastasis.

Results
This study finds that up-regulated FTX in patients with esophageal cancer correlates with poor clinical outcomes. Silencing FTX inhibits esophageal cancer cell growth and migration in vitro and tumor metastasis in vivo. miR-99a/b-3p sensitizes esophageal cancer cells to ionizing radiation by WEE1 (Wee1-like protein kinase) and ERCC1 (excision repair cross-complementation group 1) in vitro.

Conclusions
FTX promotes the malignant biological phenotype of esophageal cancer cells. Mechanistically, FTX acts as a ceRNA to regulate the transcription of WEE1 and ERCC1 by sponging hsa-miR-99a/b-3p.
Role of Z-DNA Binding Protein 1 Sensing Mitochondrial Z-DNA and Triggering Necroptosis in Oxalate-Induced Acute Kidney Injury
Authors: Chen Caiming , Xie Jingzhi , Chen Zhimin , Ye Keng , Wu Chengkun , Dai Xingchen , Yuan Ying , Lin Yujiao , Wang Yujia , Chen Hong , Wu Jianfeng , Ma Huabin , Xu Yanfang 
Published: October 2024

Key Points

Gene deletions of Zbp1, Ripk3, and Mlkl reduced severity of oxalate-induced AKI.Mice with mutation or deletion in the Z-nucleic acid sensing domain (Zα) of Z-DNA binding protein 1 were protected from AKI.Z-DNA binding protein 1 sensed mitochondrial Z-DNA through its Zα domain, recruited receptor-interacting protein kinase 3 through receptor-interacting protein homotypic interaction motif, and activated mixed lineage kinase domain-like to induce necroptosis.

Background
Calcium oxalate–induced acute kidney injury is a severe condition in which the kidneys suffer rapid damage due to the deposition of oxalate crystals. Known factors contributing to cell death induced by calcium oxalate include receptor-interacting protein kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) protein–dependent necroptosis, as well as necrosis involving peptidylprolyl isomerase F–mediated mitochondrial permeability transition. However, the detailed molecular mechanisms linking mitochondrial dysfunction to RIPK3 activation are not fully understood.

Methods
Mice with gene knockout of Zbp1, Ripk3, or Mlkl and mice with mutations in the Z-nucleic acid sensing domain of Z-DNA binding protein 1 (ZBP1) or deletion of Zα1 were used in an oxalate-induced AKI model. Proximal renal tubule cells were isolated and cultured for further investigation. Human oxalate nephropathy biopsy samples were analyzed.

Results
Specific gene deletions of Zbp1, Ripk3, or Mlkl in proximal renal tubules significantly reduced the severity of oxalate-induced AKI by preventing necroptosis and subsequent inflammation. Notably, mice with mutations in the Z-nucleic acid sensing domain of ZBP1 or deletion of Zα1 were protected from AKI. In cultured proximal tubular cells, calcium oxalate damaged mitochondria, accompanied by an increase in Bax and a decrease in BCL2 and transcription factor A, mitochondrial (TFAM), leading to the release of mitochondrial Z-DNA. ZBP1 sensed this mitochondrial Z-DNA and then recruited RIPK3 through the receptor-interacting protein homotypic interaction motifs, which in turn activated MLKL through RIPK3 phosphorylation, leading to necroptosis and contributing to AKI.

Conclusions
ZBP1 plays a critical role in sensing mitochondrial Z-DNA and initiating RIPK3/MLKL-mediated necroptosis, contributing to the development of oxalate-induced AKI.
Los actores frente a los proyectos de energía renovable en Yucatán: el Parque Fotovoltaico Ticul
Authors: García-Beltrán Yolanda 
Published: October 2024

Introducción: este trabajo tiene como base una investigación que documenta los motivos que conducen al rechazo de los megaproyectos de energía eólica y fotovoltaica en el estado de Yucatán, México. Con base en ello, este texto parte de un análisis de la estrategia de actores Objetivo: el objetivo de este texto es documentar y analizar las opiniones y posturas de los distintos actores que intervienen, en específico, en el caso del Parque Fotovoltaico Ticul, poniendo énfasis en los pobladores locales. Se busca dar respuesta a la siguiente pregunta: ¿cómo intervienen los actores comunitarios en torno a la instalación de proyectos de energía renovable en Yucatán y, en específico, en el caso del Parque Fotovoltaico Ticul, cómo interactúan, qué acciones y estrategias llevan a cabo para lograr sus objetivos? Metodología: se recurre a la metodología cualitativa. La base de la información radica en entrevistas semiestructuradas así como en la revisión y el análisis de distintas fuentes documentales Conclusiones: los resultados muestran que las alianzas entre actores forman parte esencial de las estrategias forjadas pero que éstas son cambiantes. Además, tienen lugar múltiples relaciones de poder que se materializan en el territorio, las cuales son asimétricas.
The Assertive Illocutionary Act of Khatib' Islam Preacher’ in Friday Sermons in Baiturohim Mosque of Surakarta
Authors: Maksum Sri Kuncoro DibyoSarjono Maskuri 
Published: October 2024

This research reports on an assertive illocutionary act performed by khatib ‘Islam preacher’ in Friday sermons in Baiturohim Mosque of Surakarta. This qualitative research aims to elucidate utterance's form, function, and meaning in the assertive illocutionary act of khatibs in Friday sermons at the Baiturohim Mosque of Surakarta. This research scrutinized three khatibs and data on their utterance form, function, meaning and context in the Friday sermon through the pragmatic qualitative approach. The data were collected by natural observation using audio records. The results show that assertive acts represent the main performance, with 148 tokens of illocutionary acts and for 75 assertive illocution acts. The utterance forms of assertive illocutionary act found are performative and constative. It is found 21 utterance functions of assertive illocutionary act including: to state, to compare, to illustrate, to exemplify, to tell, to think, to assume, to explain, to inform, to doubt, to affirm, to judge, to criticize, to conclude, to emphasize, to remind, to analogize, to admit, to accuse, to quote, and to interpret. Every utterance function has a meaning that evokes a religious message: Islam. Suggestions are made to research the assertive illocutionary act of the religious speakers of Christian, Catholic, Hindu or Buddha in their religious sermons.
Uncommon Presentation of Perianal Condyloma Acuminata in a Young Male: A Case Report
Authors: Christina Natalia Maria , Prasetyo Patricia Diana , Cendikiawan Albert , Wijaya Jeremiah Hilkiah 
Published: October 2024

<div class="WordSection1"><p><strong>Background:</strong> Perianal warts, also known as anogenital warts or condyloma acuminata, represent a significant health concern in the young male population. Here, we present a unique case of a large perianal wart in a 26-year-old male patient.</p><p><strong>Case Description:</strong> The patient came to the surgical clinic with complaints of an anal lump for 7 months ago. The lump first appeared in February 2019 as big as a green bean, it increased in size, bled easily and painful to be touched. The patient had a history of anal intercourse 1 month before the lump appeared. The lump size was about 8 x 5 cm and resembled “cauliflower”. Diagnosis of suspected anal papilloma was made. In July 2019, an incisional biopsy was performed, and the result showed papilloma squamosa with condyloma acuminata as a differential diagnosis. In September 2019, perianal soft tissue tumor excision with advancement flap was performed and the result showed condyloma acuminata. </p><p><strong>Discussions:</strong> The case highlights the importance of careful evaluation and diagnosis in such clinical scenarios, as the initial diagnosis of anal papilloma was later refined to condyloma acuminata based on the biopsy and surgical findings. Early detection and appropriate management are crucial in cases like this to ensure the best possible patient outcomes.</p></div>
Efektivitas Waktu Aplikasi Trichokompos dan Larutan Daun Sirih dalam Menekan Kejadian Penyakit Layu Fusarium pada Tanaman Padi Beras Merah (Oryza nivara L.)
Authors: Setiawan Mario Yudi , Budi Ismed Setya , Marsuni Yusriadi 
Published: October 2024

Beras merah (Oryza nivara L.) merupakan salah satu jenis beras yang tingkat konsumsinya semakin tinggi setiap tahunnya. Namun kendala dalam budidaya padi beras merah yang sering terjadi oleh adanya serangan dari penyakit, salah satunya adalah penyakit layu fusarium. Tujuan dari penelitian ini untuk mengetahui efektivitas pengaruh variasi waktu aplikasi trichokompos yang dikombinasikan dengan larutan daun sirih dalam menekan kejadian penyakit layu fusarium pada tanaman padi beras merah. Metode penelitian menggunakan Rancangan Acak Lengkap (RAL) yang dilaksanakan di laboratorium Fitopatologi dan rumah kaca Jurusan Hama dan Penyakit Tumbuhan Fakultas Pertanian Universitas Lambung Mangkurat Banjarbaru. Hasil penelitian menunjukan perlakuan yang diberikan trichokompos dan larutan daun sirih dengan waktu aplikasi seminggu sebelum tanam, saat tanam, dan seminggu setelah tanam mampu menekan kejadian penyakit hingga 35,00% dengan persentase keefektifan pengendalian yaitu 62,16% dibandingkan dengan perlakuan kontrol yang memiliki kejadian penyakit sebesar 92,50%. Aplikasi trichokompos dan larutan daun sirih dengan variasi waktu pada padi beras merah mampu memperpanjang masa inkubasi patogen hingga 20,25 hari dibandingkan dengan kontrol yaitu 12,53 hari. Tanaman yang diberikan aplikasi trichokompos dan larutan daun sirih juga mampu meningkatkan tinggi tanaman hingga 102,83 cm dengan jumlah sebanyak 8,78 anakan dibandingkan kontrol tanpa perlakuan yang memiliki tinggi tanaman yaitu 76,30 cm dengan jumlah anakan sebanyak 4,30 anakan.
Pengaruh Latihan Passing Berpasangan Terhadap Keterampilan Passing Bawah Permainan Bola Voli
Authors: Zaini Muhamad , Jeane Betty Kurnia Jusuf  
Published: October 2024

ABSTRAK
Tujuan studi: Penelitian ini bertujuan supaya melihat pengaruh pembelajaran passing bawah melalui latihan passing berpasangan terhadap keterampilang passing bawah pada siswa kelas IXA di SMP IT MADINA. Berdasarkan hasil pengamatan peneliti di kelas IXA, 25 dari 30 siswa belum bisa mempergunakan teknik dasar bola voli dengan baik terutama passing bawah.
Metodologi: Penelitian ini menggunakan penelitian eksperimen. Sampel pada penelitian ialah semua siswa kelas IXA di SMP IT MADINA berjumlah 30 siswa. Instrumen pada penelitian ini ialah tes passing bawah ke dinding selama 60 detik. Metode yang digunakan untuk analisis data ialah uji normalitas, homogenitas, dan uji hipotesis yang dipergunakan supaya melihat pengaruh latihan passing berpasangan terhadap keterampilan passing bawah siswa kelas IXA di SMP IT MADINA.
Hasil: Hasil penelitian menunjukan terdapat perbedaan setelah diberikan treatment berupa passing berpasangan. Pre-test menghasilkan skor rata-rata 13,4 (kategori kurang). Setelah diberikan treatment, post-test menghasilkan peningkatan skor menjadi 24,31 (kategori baik). Disimpulkan adanya pengaruh metode latihan passing berpasangan pada keterampilan passing bawah bola voli siswa kelas IXA di SMP IT MADINA.
Manfaat: Penelitian ini bisa memberikannya pengembangan ilmu latihan bola voli khususnya kemampuan passing bawah dengan metode passing berpasangan.
Model Permainan Trampoline Untuk Anak Usia Dini 6 - 8 tahun
Authors: Ahmad Fikri  Mujahid  , Sri Nuraini  , Siregar Nofi Marlina 
Published: October 2024

bertujuan untuk mengembangkan model permainan trampoline di bounce street asia untuk anak usia 6 – 8 tahun, tempat penelitian berletak di Kelapa Gading Jakarta Utara, sentra bisnis, Jalan, Jl. Artha Gading Sel. No.Kav 8, RT.18/RW.8, Klp. Gading Bar., Kec. Klp. Gading, Jkt Utara, Daerah Khusus Ibukota Jakarta. Waktu penelitian selama bulan Desember 2022. Metode penelitian ini menggunakan metode penelitian ADDIE, dimana penelitian menggunakan 5 tahapan yaitu, analisis, desain, pengembangan model, pelaksanaan model, evaluasi. Hasil penelitian menghasilkan produk yang berupa model permainan trampoline yang telah di revisi oleh ahli permainan dan ahli trampoline sebanyak 10 model yang di implementasikan kepada sebanyak 15 orang anak. Berdasarkan hasil penelitian menunjukan bahwa model permainan trampoline untuk anak usia 6 – 8 tahun ini dapat menjadi media untuk dimainkan terutama untuk meningkatkan motivasi bermain anak saat bermain trampoline, sehingga dapat memberikan kontribusi yang baik, berdasarkan hasil penelitian model permainan trampoline untuk anak usia 6 – 8 tahun dapat dikembangkan dan dapat diterapkan kepada anak-anak
(σ,τ )– (J,R) – DERIVATIONS ON JORDAN IDEALS
Authors: Saed Ikram A. 
Published: October 2024

لتكن R حلقة تجميعية مركزها Z(R). نتائج Bell و Kappe المعروفة والمتعلقة بالمشتقات على الحلقات الاولية درست بتوسع من قبل العديد من الباحثين، بعض هؤلاء الباحثين عمموا هذه النتائج لمشتقة - a مثلYenigual و Arguc والبعض الاخر عمموا هذه النتائج لمشتقة - (σ,τ )– (J,R) مثل M.Asharf.
ان الهدف الرئيسي لهذا البحث هو دراسة تأثير المشتقة – (σ,τ )– (J,R) والمشتقة من اليسار – (σ,τ )– (J,R) على مثاليات جوردان.