bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robotic thoracic surgery: lessons learned from the first 1,000 procedures
Authors: Durand Marion , Nguyen Lee S. , Mbadinga Frankie , Pryshchepau Maksim , Portefaix Hadrien , Chaabane Nouha , Ropert Stanislas , Khen-Dunlop Naziha 
Published: September 2024

IntroductionThe aim of this study was to evaluate the impact of the thoracic robotic approach in a high-volume center regarding procedures and clinical outcomes after 1,000 procedures.MethodsIn a single-center subset of the Epithor® database, a prospective cohort database of French thoracic surgery, we analyzed procedural characteristics and clinical outcomes from February 2014 to April 2023. A surgical technique for lung surgery was conducted with a four-arm closed chest with the port access approach and vascular sewing and knotting were preferred over stapling. Statistical analysis was performed using the Chi-2 test for discontinuous variables and the Mann–Whitney–Wilcoxon test for continuous variables. Tests were considered significant for a p-value &lt;0.05.ResultsRobotic thoracic surgery was used in anatomical lung resection in 85% of the cases. Over the study period, 1,067 patients underwent robotic surgery, of which 509 had lobectomies and 391 segmentectomies. In the segmentectomy group vs. lobectomy group we observed a shorter length of stay (9 ± 7 vs. 7 ± 5.6 days, p &lt; 0.001), a shorter surgery time (99 ± 24 vs. 116 ± 38 min, p &lt; 0.001) a lower conversion rate (n = 2 vs. n = 17, p = 0.004), and a lower complication rate (28% vs. 40%, p = 0.009, mainly Clavien–Dindo II, 18% and 28%, respectively). For cancer treatment surgery, we found more previous cancer in the segmentectomy group (48% vs. 26%, p &lt; 0.001). We also observed a progressive change of lobectomy vs. segmentectomy from 80%/20% to 30%/70% over the 9 years.DiscussionA robotic platform is an appropriate tool to perform anatomical lung resection and especially to develop a safe and systematic approach to lung-sparing sub-lobar resection.
Hidatidosis pélvica primaria como presentación inhabitual. Reporte de un caso
Authors: Diaz Gasaly Fatme Valentina , Mansilla Espinosa Juan Andrés , Muñoz Pérez Nelson 
Published: September 2024

Introduccion: La hidatidosis o equinococosis quística, es una zoonosis parasitaria causada por la forma larvaria del cestodo Echinococcus granulosus y actualmente se clasifica como la principal zoonosis endémica en Chile. El órgano comúnmente afectado es el hígado (59 -75 % de los casos), siendo la hidatidosis pélvica primaria extremadamente infrecuente (<1%), sin embargo en países endémicos debe ser considerada en los diagnósticos diferenciales de lesiones quísticas de la pelvis.Caso clínico: se presenta un caso clínico de hidatidosis pélvica primaria con extensión a la región glútea izquierda, los estudios complementarios no evidencian hidatidosis hepática, pulmonar u otra ubicación. Se discutirá sobre la sospecha, diagnóstico y manejo de ésta, en consideración a su infrecuente incidencia.
Pancreatoduodenectomía con reconstrucción pancreática con técnica de Blumgart.
Authors: Losada Morales Hector Fabio , Portillo López Norberto Andres , Curitol Sonia , Muñoz Khatalina , Troncoso Andres , Arias Oriel 
Published: September 2024

Introducción: La pancreatoduodenectomía (PD) es una cirugía destacada por su complejidad y alta mortalidad perioperatoria, que se ha reducido del 17% a 1% y la morbilidad del 60% a un 30%. Uno de los principales desafíos es la anastomosis pancreática.Objetivo: Describir los resultados quirúrgicos, morbilidad y mortalidad de pacientes sometidos a pancreatoduodenectomía abierta con técnica de Blumgart, en el Hospital de Temuco entre los años 2015 - 2021.Materiales y Método: Serie de casos con seguimiento desde 2015 hasta 2021. Se incluyeron los pacientes sometidos a operación de Whipple abierta con técnica de reconstrucción pancreática con pancreato-yeyuno-anastomosis con técnica de Blumgart, por el equipo de cirugía hepatobiliar del Hospital de Temuco. La base de datos se realizó de manera prospectiva en Excel. Se utilizó estadística descriptiva con el uso de medidas de tendencia central y dispersión en el programa Stata® 13.0. Resultados: Serie de casos de 52 pacientes, 30 (56,9%) de género femenino y 22 (43,1%) de género masculino. La edad promedio fue de 60,5 años ± 11,8 años. Dos pacientes fueron sometidos a PD de urgencia. La morbilidad fue de 51,9% y la mortalidad de 3,8%. La tasa de fístula grado B/C fue de un 25%.Conclusión: La serie de pacientes con PD con reconstrucción pancreática con técnica de Blumgart presenta una morbilidad de 51,9% mayor a la reportada en la literatura y mortalidad comparables a las series nacionales e internacionales. Consideramos que el aumento de la morbilidad se puede asociar a los casos de PD de urgencia.
DESAFIOS E OPORTUNIDADES NA SAÚDE PÚBLICA EM REGIÕES RURAIS: AVALIAÇÃO DOS OBSTÁCULOS ENFRENTADOS
Authors: Melo Ana Beatriz Oliveira de , Nascimento Maria Eduarda Bezerra do , Aguiar Priscila Silva , Esteves Ryan Farias , Oliveira Jullia Martins de , Façanha Eliomara Brito , Siqueira Helainy de Souza , Cavalcanti Ana Luiza Batista , Campanate Acsa Lia , Silva Bárbara Tatiany de Moraes , Lima Vanessa de Sousa Leal , Vieira Luma de Souza 
Published: September 2024

Introdução: A saúde pública em regiões rurais enfrenta uma série de desafios que impactam diretamente o acesso e a qualidade dos serviços oferecidos. Esses desafios incluem a escassez de profissionais de saúde, infraestrutura inadequada, distâncias geográficas, além de barreiras socioeconômicas e culturais. Por outro lado, as regiões rurais também oferecem oportunidades únicas, como o fortalecimento de redes comunitárias, iniciativas de saúde local e a adaptação de estratégias de atendimento voltadas para as especificidades dessas populações. Objetivo: Identificar e avaliar os principais obstáculos enfrentados pelos serviços de saúde pública em regiões rurais. Metodologia: A pesquisa foi realizada através do acesso online nas bases de dados National Library of Medicine (MEDLINE), Scientific Electronic Library Online (SCIELO), literatura latino-americana e do Caribe em Ciências da Saúde (LILACS) no mês de agosto de 2024. Resultados e Discussão: Os resultados deste estudo indicam que os principais desafios enfrentados pela saúde pública em regiões rurais incluem a escassez de profissionais qualificados, dificuldades de transporte e acesso, além de limitações na infraestrutura. No entanto, foram identificadas oportunidades de fortalecimento por meio de estratégias como a telemedicina, parcerias comunitárias e a capacitação local de agentes de saúde. A discussão sugere que, apesar das barreiras, políticas de saúde adaptadas à realidade rural, aliadas ao uso de novas tecnologias, podem melhorar significativamente o atendimento e promover maior equidade no acesso aos serviços. Considerações Finais: Em síntese, embora as regiões rurais enfrentem desafios significativos na saúde pública, como a falta de infraestrutura e profissionais, há oportunidades promissoras para superar essas barreiras. O investimento em telemedicina, capacitação local e políticas de saúde específicas para essas áreas pode melhorar o acesso e a qualidade dos serviços, promovendo uma saúde mais equitativa e sustentável.
APNEIA OBSTRUTIVA DO SONO COMO FATOR DE RISCO PARA HIPERTENSÃO ARTERIAL: UMA REVISÃO DA LITERATURA
Authors: Lima Pedro Paulo Gusmão de , Costa Fabiany Almada , Lima Gabriela Gusmão de , Junior Glauco Mol Santos , Neto Ivan Moreira , Mourão Matheus Marques , Silva Maria Clara Ataide Pereira , Guimarães Fernanda Alves , Lima Arthur Gabriel Martins e 
Published: September 2024

A apneia obstrutiva do sono (AOS) é um distúrbio de elevada prevalência na população mundial, o qual se caracteriza por diversos intervalos de obstrução das vias aéreas superiores e interrupção do sono durante o repouso. Este distúrbio traz diversas consequências negativas, como o desenvolvimento de patologias cardiovasculares, elevação da pressão arterial, entre outras. Nesse contexto, estudos têm sido desenvolvidos com pacientes portadores da síndrome da apneia obstrutiva do sono, com o objetivo de investigar esta condição e, dentre os resultados, têm-se obtido que a AOS tem influência direta no desenvolvimento da hipertensão arterial e que o seu tratamento com diferentes dispositivos cursa com desfechos positivos na redução dos níveis pressóricos. Dessa maneira, tendo em vista as problemáticas diretamente desencadeadas pela hipertensão arterial, é notável a importância de conhecer esta correlação e abordá-la adequadamente para promover saúde, qualidade de vida e desfechos cardiovasculares favoráveis aos pacientes acometidos.
Penerapan Strategi Rebranding Pada Desa Wisata Kampung Terih Untuk Meningkatkan Jumlah Wisatawan Menggunakan Metode MDLC
Authors: . Deli , Hartanto Veri 
Published: September 2024

Desa Wisata Kampung Terih merupakan kampung tua yang memiliki luas sekitar 12 hektar yang terletak pada Kelurahan Sambau, Kecamatan Nongsa. Kampung Terih dikembangkan jadi destinasi wisata sejak tahun 2017 tepatnya pada 10 Desember, yang dikelola menjadi destinasi wisata digital itu milik satu keluarga yang terdiri dari empat orang. Desa Wisata Kampung Terih dibangun dengan pelantar kayu dengan konsep klasik di antara rimbunan hutan bakau yang ada disana, selain itu juga terdapat beberapa pondok dan spot foto yang instagramable. Jam operasional untuk. Desa Wisata Kampung Terih beroperasional setiap hari mulai dari pukul 08:00-18:00 WIB. Masalah yang dihadapi oleh Desa Wisata Kampung Terih adalah Semenjak terjadinya pandemi COVID-19, Desa Wisata Kampung Terih menjadi sepi dan wisatawan luar berkurang mengunjungi, hanya terdapat wisatawan lokal. Untuk meningkatkan pengunjungan wisatawan dan dikenal oleh masyarakat luas, Universitas Internasional Batam melakukan kerjasama dengan Desa Wisata Kampung Terih untuk rebranding melalui video promosi pada Desa Wisata Kampung Terih yang akan dirancang oleh penulis dengan menggunakan metode Multimedia Development Life Cyle (MDLC) yang terdapat enam tahapan yaitu yaitu konsep, perancangan, pengumpulan bahan, pembuatan, pengujian, dan distribusi. Video ini diharapkan dapat dijadikan sebagai media promosi dan informasi yang efektif untuk memperkenalkan Desa Wisata Kampung Terih kepada masyarakat dan meningkatan minat wisatawan untuk berkunjung
Correlation between the neuroendocrine axis, microbial species, inflammatory response, and gastrointestinal symptoms in irritable bowel syndrome
Authors: Zhang Xin , Jin Wei-Wei , Wang Hong-Gang 
Published: September 2024

BACKGROUND
This study examines the complex relationships among the neuroendocrine axis, gut microbiome, inflammatory responses, and gastrointestinal symptoms in patients with irritable bowel syndrome (IBS). The findings provide new insights into the pathophysiology of IBS and suggest potential therapeutic targets for improving patient outcomes.
AIM
To investigate the interactions between the neuroendocrine axis, gut microbiome, inflammation, and gastrointestinal symptoms in patients with IBS.
METHODS
Patients diagnosed with IBS between January 2022 and January 2023 were selected for the study. Healthy individuals undergoing routine check-ups during the same period served as the control group. Data were collected on neuroendocrine hormone levels, gut microbiome profiles, inflammatory biomarkers, and gastrointestinal symptomatology to analyze their interrelations and their potential roles in IBS pathogenesis.
RESULTS
IBS patients exhibited significant dysregulation of the neuroendocrine axis, with altered levels of cortisol, serotonin, and neuropeptides compared to healthy controls. The gut microbiome of IBS patients showed reduced diversity and specific alterations in bacterial genera, including Bifidobacterium , Lactobacillus , and Faecalibacterium , which were associated with neuroendocrine disturbances. Additionally, elevated levels of inflammatory markers, such as C-reactive protein, interleukin-6, and tumor necrosis factor-α, were observed and correlated with the severity of gastrointestinal symptoms like abdominal pain, bloating, and altered bowel habits.
CONCLUSION
The findings suggest that targeting the neuroendocrine axis, gut microbiome, and inflammatory pathways may offer novel therapeutic strategies to alleviate symptoms and improve the quality of life in IBS patients.
Impact of metabolic syndrome components on clinical outcomes in hypertriglyceridemia-induced acute pancreatitis
Authors: Fu Zhen-Hua , Zhao Zi-Yue , Liang Yao-Bing , Cheng Dong-Yu , Luo Jian-Ming , Jiang Hai-Xing , Qin Shan-Yu 
Published: September 2024

BACKGROUND
The incidence of hypertriglyceridemia (HTG)-induced acute pancreatitis (AP) is steadily increasing in China, becoming the second leading cause of AP. Clinical complications and outcomes associated with HTG-AP are generally more severe than those seen in AP caused by other etiologies. HTG-AP is closely linked to metabolic dysfunction and frequently coexists with metabolic syndrome or its components. However, the impact of metabolic syndrome components on HTG-AP clinical outcomes remains unclear.
AIM
To investigate the impact of metabolic syndrome component burden on clinical outcomes in HTG-AP.
METHODS
In this retrospective study of 255 patients diagnosed with HTG-AP at the First Affiliated Hospital of Guangxi Medical University, we collected data on patient demographics, clinical scores, complications, and clinical outcomes. Subsequently, we analyzed the influence of the presence and number of individual metabolic syndrome components, including obesity, hyperglycemia, hypertension, and low high-density lipoprotein cholesterol (HDL-C), on the aforementioned parameters in HTG-AP patients.
RESULTS
This study found that metabolic syndrome components were associated with an increased risk of various complications in HTG-AP, with low HDL-C being the most significant risk factor for clinical outcomes. The risk of complications increased with the number of metabolic syndrome components. Adjusted for age and sex, patients with high-component metabolic syndrome had significantly higher risks of renal failure [odds ratio (OR) = 3.02, 95%CI: 1.12-8.11)], SAP (OR = 5.05, 95%CI: 2.04-12.49), and intensive care unit admission (OR = 6.41, 95%CI: 2.42-16.97) compared to those without metabolic syndrome.
CONCLUSION
The coexistence of multiple metabolic syndrome components can synergistically worsen the clinical course of HTG-AP, making it crucial to monitor these components for effective disease management.
Absence of High-mass Prestellar Cores in the Orion Giant Molecular Cloud
Authors: Jiao Wenyu , Wang Ke , Xu Fengwei 
Published: September 2024

Abstract
A fundamental difference between “core-fed” and “clump-fed” star-formation theories lies in the existence or absence of high-mass cores at the prestellar stage. However, only a handful of such cores have been observed. Here, different than previous search in distributed star-formation regions in the Galactic plane, we search for high-mass prestellar cores in the Orion GMC, by observing the seven most massive starless cores selected from previous deep continuum surveys. We present ALMA Atacama Compact Array Band 6 and Band 7 continuum and line observations toward the seven cores, in which we identify nine dense cores at both bands. The derived maximum core mass is less than 11 M
⊙, based on different dust temperatures. We find no high-mass prestellar cores in this sample, aligning with the results of previous surveys, thereby challenging the existence of such cores in Orion. Outside Orion, further detailed studies are needed for remaining high-mass prestellar core candidates to confirm their status as massive, starless cores.
Unveiling the Distant Universe: Characterizing z ≥ 9 Galaxies in the First Epoch of COSMOS-Web
Authors: Franco Maximilien , Akins Hollis B. , Casey Caitlin M. , Finkelstein Steven L. , Shuntov Marko , Chworowsky Katherine , Faisst Andreas L. , Fujimoto Seiji , Ilbert Olivier , Koekemoer Anton M. , Liu Daizhong , Lovell Christopher C. , Maraston Claudia , McCracken Henry Joy , McKinney Jed , Robertson Brant E. , Bagley Micaela B. , Champagne Jaclyn B. , Cooper Olivia R. , Ding Xuheng , Drakos Nicole E. , Enia Andrea , Gillman Steven , Gozaliasl Ghassem , Harish Santosh , Hayward Christopher C. , Hirschmann Michaela , Jin Shuowen , Kartaltepe Jeyhan S. , Kokorev Vasily , Laigle Clotilde , Long Arianna S. , Magdis Georgios , Mahler Guillaume , Martin Crystal L. , Massey Richard , Mobasher Bahram , Paquereau Louise , Renzini Alvio , Rhodes Jason , Rich R. Michael , Sheth Kartik , Silverman John D. , Sparre Martin , Talia Margherita , Trakhtenbrot Benny , Valentino Francesco , Vijayan Aswin P. , Wilkins Stephen M. , Yang Lilan , Zavala Jorge A. 
Published: September 2024

Abstract
We report the identification of 15 galaxy candidates at z ≥ 9 using the initial COSMOS-Web JWST observations over 77 arcmin2 through four Near Infrared Camera filters (F115W, F150W, F277W, and F444W) with an overlap with the Mid-Infrared Imager (F770W) of 8.7 arcmin2. We fit the sample using several publicly available spectral energy distribution (SED) fitting and photometric redshift codes and determine their redshifts between z = 9.3 and z = 10.9 (〈z〉 = 10.0), UV magnitudes between M
UV = −21.2 and −19.5 (with 〈M
UV〉 = −20.2), and rest-frame UV slopes (〈β〉 = −2.4). These galaxies are, on average, more luminous than most z ≥ 9 candidates discovered by JWST so far in the literature, while exhibiting similar blue colors in their rest-frame UV. The rest-frame UV slopes derived from SED fitting are blue (β ∼ [−2.0, −2.7]) without reaching extremely blue values as reported in other recent studies at these redshifts. The blue color is consistent with models that suggest the underlying stellar population is not yet fully enriched in metals like similarly luminous galaxies in the lower-redshift Universe. The derived stellar masses with

〈

log

10

(

M
⋆/M
⊙)〉 ≈ 8–9 are not in tension with the standard Lambda cold dark matter (ΛCDM) model, and our measurement of the volume density of such UV-luminous galaxies aligns well with previously measured values presented in the literature at z ∼ 9–10. Our sample of galaxies, although compact, is significantly resolved.
Turbulence, Waves, and Taylor’s Hypothesis for Heliosheath Observations
Authors: Zhao L.-L. , Zank G. P. , Opher M. , Zieger B. , Li H. , Florinski V. , Adhikari L. , Zhu X. , Nakanotani M. 
Published: September 2024

Abstract
Magnetic field fluctuations measured in the heliosheath by the Voyager spacecraft are often characterized as compressible, as indicated by a strong fluctuating component parallel to the mean magnetic field. However, the interpretation of the turbulence data faces the caveat that the standard Taylor’s hypothesis is invalid because the solar wind flow velocity in the heliosheath becomes subsonic and slower than the fast magnetosonic speed, given the contributions from hot pickup ions (PUIs) in the heliosheath. We attempt to overcome this caveat by introducing a 4D frequency-wavenumber spectral modeling of turbulence, which is essentially a decomposition of different wave modes following their respective dispersion relations. Isotropic Alfvén and fast mode turbulence are considered to represent the heliosheath fluctuations. We also include two dispersive fast wave modes derived from a three-fluid theory. We find that (1) magnetic fluctuations in the inner heliosheath are less compressible than previously thought, an isotropic turbulence spectral model with about 25% in compressible fluctuation power is consistent with the observed magnetic compressibility in the heliosheath; (2) the hot PUI component and the relatively cold solar wind ions induce two dispersive fast magnetosonic wave branches in the perpendicular propagation limit, PUI fast wave may account for the spectral bump near the proton gyrofrequency in the observable spectrum; (3) it is possible that the turbulence wavenumber spectrum is not Kolmogorov-like although the observed frequency spectrum has a −5/3 power-law index, depending on the partitioning of power among the various wave modes, and this partitioning may change with wavenumber.
Reactive Molecular Dynamics Simulations of Micrometeoroid Bombardment for Space Weathering of Asteroid (162173) Ryugu
Authors: Shoji Daigo 
Published: September 2024

Abstract
Remote sensing observations by Hayabusa2 and laboratory measurements have revealed that the phyllosilicates on asteroid (162173) Ryugu are dehydrated/dehydroxylated due to space weathering. Reactive molecular dynamics simulations were performed to evaluate the magnitude of the dehydroxylation of Mg-rich serpentine by micrometeoroid impacts. When micrometeoroids were not coupled with interplanetary magnetic fields, serpentine could be dehydroxylated by micrometeoroids as small as 2 nm in size. In particular, ∼200 O–H bonds dissociated when the meteoroids were derived from cometary activity (the impact velocity was ∼20 km s−1). When nano-sized dust particles were accelerated to ∼300 km s−1 by the magnetic fields of solar wind plasma, the number of dissociated O–H bonds increased by 1 order of magnitude. Consequently, even 1 nm-sized dust particles can contribute to the space weathering of Ryugu. In all cases, Si–OH, H2O, and free OH were generated from the hydroxyls initially connected to Mg, which could partially offset dehydration. Despite the limitations of our computational resources, which restricted the simulation timescale to 1 ps, reactive molecular dynamic simulations demonstrated that micrometeoroid bombardment could influence the space weathering of asteroids.
Midwives’ compliance with post-exposure prophylaxis guidelines in Tshwane District, South Africa
Authors: Matlala Mosehle S. , Lumadi Thanyani G. 
Published: September 2024

Background: Human immunodeficiency virus (HIV) remains a major public health concern. Midwifery practitioners as frontline healthcare workers (HCWs) remain susceptible to occupational exposure to infections while performing their routine duties. It is estimated that 90% of occupational exposures occur because of a lack of awareness and training regarding prevention and measures to be taken in case of accidental exposure.Objectives: The study aimed to assess the knowledge, attitudes and compliance of midwifery practitioners regarding post-exposure prophylaxis (PEP) guidelines.Method: Concurrent mixed-methods research approach with qualitative nested in quantitative design was followed. A random simple sampling technique was used to collect quantitative data from 71 midwifery practitioners. Simultaneously, a purposive non-probability sampling technique was used for the qualitative approach with two occupational health and safety (OHS) practitioners and 13 midwifery practitioners. Data were collected through questionnaires and semi-structured interviews. Quantitative data were analysed with SPSS version 24 and presented in tables and figures, and thematic analysis was employed for the qualitative strand.Results: The midwifery practitioners have good knowledge about PEP for HIV. However, the study revealed the underreporting of accidental exposures to blood and body fluids (BBFs) and the underutilisation of available PEP services.Conclusion: Maternity units are high-risk clinical environments. Underreporting of incidents of exposure remains prevalent among midwifery practitioners.Contribution: The findings will inform policy development structures and hospital management regarding knowledge and implementation gaps related to PEP guidelines in the specific hospitals. Strategies to improve compliance with PEP among midwifery practitioners were developed as a derivative from study findings.