bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical evaluation of time‐of‐flight MR angiography with sparse undersampling and iterative reconstruction for cerebral aneurysms
Authors: Fushimi Yasutaka , Okada Tomohisa , Kikuchi Takayuki , Yamamoto Akira , Okada Tsutomu , Yamamoto Takayuki , Schmidt Michaela , Yoshida Kazumichi , Miyamoto Susumu , Togashi Kaori 
Published: August 2017

Compressed sensing (CS) MRI has just been introduced to research areas as an innovative approach to accelerate MRI. CS is expected to achieve higher k‐space undersampling by exploiting the underlying sparsity in an appropriate transform domain. MR angiography (MRA) provides high spatial resolution information on arteries; however, a relatively long acquisition time is necessary to cover a wide volume. Reduction of acquisition time by CS for time‐of‐flight (TOF) MR angiography (Sparse‐TOF) is beneficial in clinical examinations; therefore, the clinical validity of Sparse‐TOF needs to be investigated. The aim of this study was to compare the diagnostic capability of TOF MRA between parallel imaging (PI)‐TOF with an acceleration factor of 3 (annotated as 3×) and Sparse‐TOF (3× and 5×) in patients with cerebral aneurysms. PI‐TOF (3×) and Sparse‐TOF (3× and 5×) imaging were performed in 20 patients using a 3 T MRI system. Aneurysms in PI‐TOF (3×) and Sparse‐TOF (3× and 5×) were blindly rated as visible or scarcely visible by neuroradiologists. The neck, height and width of aneurysms were also measured. Twenty‐six aneurysms were visualized and rated as visible in PI‐TOF (3×) and Sparse‐TOF (3× and 5×), with excellent agreement between two raters. No significant differences were found in measured neck, height or width of aneurysms among them. Sparse‐TOF (3× and 5×) were acquired and reconstructed within 6 min, and cerebral aneurysms were visible in both of them with equivalent quality to PI‐TOF (3×). Sparse‐TOF (5×) is a good alternative to PI‐TOF (3×) to visualize cerebral aneurysms.
Converging evidence that subliminal evaluative conditioning does not affect self‐esteem or cardiovascular activity
Authors: Versluis Anke , Verkuil Bart , Brosschot Jos F. 
Published: August 2017

AbstractSelf‐esteem moderates the relationship between stress and (cardiovascular) health, with low self‐esteem potentially exacerbating the impact of stressors. Boosting self‐esteem may therefore help to buffer against stress. Subliminal evaluative conditioning (SEC), which subliminally couples self‐words with positive words, has previously been successfully used to boost self‐esteem, but the existing studies are in need of replication. In this article, we aimed to replicate and extend previous SEC studies. The first 2 experiments simultaneously examined whether SEC increased self‐esteem (Experiment 1, n = 84) and reduced cardiovascular reactivity to a stressor in high worriers (Experiment 2, n = 77). On the basis of these results, the 3rd experiment was set up to examine whether an adjusted personalized SEC task increased self‐esteem and reduced cardiac activity in high worriers (n = 81). Across the 3 experiments, no effects were found of SEC on implicit or explicit self‐esteem or affect or on cardiovascular (re)activity compared to a control condition in which the self was coupled with neutral words. The results do not support the use of the subliminal intervention in its current format. As stress is highly prevalent, future studies should focus on developing other cost‐effective and evidence‐based interventions.
Effect of surface roughness on static and dynamic characteristics of MHD couple stress lubrication of inclined plane slider bearing
Authors: Naduvinamani N. B. , Siddangouda A. , Patil S. 
Published: August 2017

AbstractThe effect of surface roughness on static and dynamic characteristics of inclined plane slider bearing lubricated with couple stress fluid in the presence of magnetic field is theoretically analysed. The modified stochastic MHD couple stress Reynolds type equation is derived on the basis of Christensen stochastic theory by considering two types of one‐dimensional roughness patterns namely longitudinal and transverse. Expressions for steady pressure and load, dynamic stiffness, and damping coefficients are obtained for both the types of roughness patterns. Compared to smooth surface, transverse roughness pattern provides larger load carrying capacity, dynamic stiffness, and damping coefficients whereas longitudinal roughness pattern has adverse effects. Further, the presence of couple stress and applied magnetic field improves the bearing performance.
Diagnostic Criteria for Assessment by General Practitioners of Patients Injured in Radiation Incidents and Cases of Radiological Terrorism
Authors: Zahariev Vili , Hristov Nikolai 
Published: August 2017

AbstractThe general practitioner is an important figure in the provision of medical care during radiation incidents and cases of radiological terrorism. Knowing the nature of the radiation injury is essential for correct diagnosis and treatment. Insufficient knowledge of most physicians, and of general practitioners in particular, on the clinical manifestation of radiation injuries is the reason such conditions remain unrecognized and improperly treated. We suggest some simple diagnostic criteria for assessment of the injured by general practitioners, based on the results of our own studies and on the recommendations of prominent international organizations. (Disaster Med Public Health Preparedness. 2018;12:507–512)
Physical descriptions of the Beechey Island headboards
Authors: Hansen Todd 
Published: August 2017

ABSTRACTIn August 2016, the author was able to personally examine the five Beechey Island Franklin era gravesite headboards, in the collections of the Government of Nunavut and currently preserved at the Prince of Wales Northern Heritage Center in Yellowknife, NT, Canada. Except for the inscriptions, there appears to be relatively little physical description actually published in the literature, and this article summarises those observations and some conclusions drawn from this examination.
Believing God: an account of faith as personal trust
Authors: MICHON CYRILLE 
Published: August 2017

AbstractThe affective view of faith, as opposed to the doxastic or cognitive view, giving more importance to goodwill than to belief content, has received much support in recent philosophy of religion, including from Richard Swinburne. Swinburne's concept of faith is no less rational than his concept of religious belief, but its rationality is that of an action or of a practically oriented attitude, aiming at the goals of religion, compatible with religious disbelief (belief that the religious content one has faith in is probably false) and even with atheism. I argue that this paradoxical stance, which hardly squares with the Christian tradition, can be avoided, while keeping to an affective view of faith, if we give more weight to the idea that faith is first an answer given to a telling, on the basis of personal trust of the hearer in the authority of the teller – a personal account as opposed to a propositional account of faith.
X-ray and ion emission studies from subnanosecond laser-irradiated SiO2 aerogel foam targets
Authors: Kaur C. , Chaurasia S. , Pisal A.A. , Rossall A.K. , Munda D.S. , Venkateswara Rao A. , Deo M.N. 
Published: August 2017

AbstractIn this experiment, a comparative study of ion and X-ray emission from both a SiO2 aerogel foam and a quartz target is performed. The experiment is performed using Nd:glass laser system operated at laser energy up to 15 J with a pulse duration of 500 ps with focusable intensity of 1013–1014 W/cm2 on target. X-ray fluxes in different spectral ranges (soft and hard) are measured by using X-ray diodes covered with Al filters of thickness 5 µm (0.9–1.56 keV) and 20 µm (3.4–16 keV). A 2.5 times enhancement in soft X-ray flux (0.9–1.56 keV) and a decrease of 1.8 times in hard X rays (3.4–16 keV) for 50 mg/cc SiO2 aerogel foam is observed compared with the solid quartz. A decrease in the flux of the K-shell line emission spectrum of soft X rays is noticed in the case of the foam targets. The high-resolution K-shell spectra (He-like) of Si ions in both the cases are analyzed for the determination of plasma parameters by comparing with FLYCHK simulations. The estimated plasma temperature and density are Tc = 180 eV, ne = 7 × 1020 cm−3 and Tc = 190 eV, ne = 4 × 1020 cm−3 for quartz and SiO2 aerogel foam, respectively. To measure the evolution of the plasma moving away from the targets, four identical ion collectors are placed at different angles (22.5, 30, 45, and 67.5°) from target normal. The angular distribution of the thermal ions are scaled as cosnθ with respect to target normal, where n = 3.8 and 4.8 for the foam and quartz, respectively. The experimental plasma volume measured from the ion collectors and shadowgraphy images are verified by a two-dimensional Eulerian radiative–hydrodynamic simulation (POLLUX code).
THE ROLE OF PROCEDURAL LEARNING ABILITY IN AUTOMATIZATION OF L2 MORPHOLOGY UNDER DIFFERENT LEARNING SCHEDULES
Authors: Suzuki Yuichi 
Published: August 2017

AbstractThis paper reports on the reanalysis of Suzuki’s (2017) experiment and investigated the extent to which learning schedules influence automatization of second language (L2) morphology. Sixty participants were separated into two groups, which studied morphological rules for oral production under short-spacing (3.3-day intervals) and long-spacing learning conditions (7-day intervals). Their oral production test performance resulted in two measures of automatization: reaction time (RT) as an index of speedup and coefficient of variance (CV) as an index of stability/restructuring. The results showed that, while RT of both groups declined significantly after the training, the 3.3-day group exhibited greater propensity for restructuring than the 7-day group. Furthermore, procedural learning ability measured by the Tower of London task was significantly associated with RT, but not with CV, in the 3.3-day group only. These findings suggest that learning schedules and procedural learning ability influence different stages of automatization of L2 morphological learning.
Dual Contrast - Magnetic Resonance Fingerprinting (DC-MRF): A Platform for Simultaneous Quantification of Multiple MRI Contrast Agents
Authors: Anderson Christian E. , Donnola Shannon B. , Jiang Yun , Batesole Joshua , Darrah Rebecca , Drumm Mitchell L. , Brady-Kalnay Susann M. , Steinmetz Nicole F. , Yu Xin , Griswold Mark A. , Flask Chris A. 
Published: August 2017

AbstractInjectable Magnetic Resonance Imaging (MRI) contrast agents have been widely used to provide critical assessments of disease for both clinical and basic science imaging research studies. The scope of available MRI contrast agents has expanded over the years with the emergence of molecular imaging contrast agents specifically targeted to biological markers. Unfortunately, synergistic application of more than a single molecular contrast agent has been limited by MRI’s ability to only dynamically measure a single agent at a time. In this study, a new Dual Contrast - Magnetic Resonance Fingerprinting (DC – MRF) methodology is described that can detect and independently quantify the local concentration of multiple MRI contrast agents following simultaneous administration. This “multi-color” MRI methodology provides the opportunity to monitor multiple molecular species simultaneously and provides a practical, quantitative imaging framework for the eventual clinical translation of molecular imaging contrast agents.
Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex
Authors: Tada Hirobumi , Miyazaki Tomoyuki , Takemoto Kiwamu , Jitsuki Susumu , Nakajima Waki , Koide Mayu , Yamamoto Naoko , Taguchi Akiko , Kawai Honami , Komiya Kasane , Suyama Kumiko , Abe Hiroki , Sano Akane , Takahashi Takuya 
Published: August 2017

AbstractExposure to a stressful environment early in life can cause psychiatric disorders by disrupting circuit formation. Actin plays central roles in regulating neuronal structure and protein trafficking. We have recently reported that neonatal isolation inactivated ADF/cofilin, the actin depolymerizing factor, resulted in a reduced actin dynamics at spines and an attenuation of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptor delivery in the juvenile rat medial prefrontal cortex (mPFC), leading to altered social behaviours. Here, we investigated the impact of neonatal social isolation in the developing rat barrel cortex. Similar to the mPFC study, we detected an increase in stable actin fraction in spines and this resulted in a decreased synaptic AMPA receptor delivery. Thus, we conclude that early life social isolation affects multiple cortical areas with common molecular changes.
Calf Spleen Extractive Injection protects mice against cyclophosphamide-induced hematopoietic injury through G-CSF-mediated JAK2/STAT3 signaling
Authors: Lu Wenqian , Jia Dongxu , An Shengshu , Mu Ming , Qiao Xinan , Liu Yan , Li Xin , Wang Di 
Published: August 2017

AbstractCalf Spleen Extractive Injection (CSEI), extracted from the spleen of healthy cows (within 24 hours of birth), is a small-peptide-enriched extraction and often used as an ancillary agent in cancer therapy. This study evaluated the hematopoietic function of CSEI and its underlying mechanisms, principally in CHRF, K562 cells, BMNCs and a mouse model of cyclophosphamide (CTX)-induced hematopoietic suppression. CSEI promoted the proliferation and differentiation of CHRF and K562 cells, activated hematopoietic- and proliferation-related factors RSK1p90, ELK1 and c-Myc, and facilitated the expression of differentiation- and maturation-related transcription factors GATA-1, GATA-2. In the mice with hematopoietic suppression, 3 weeks of CSEI administration enhanced the bodyweights and thymus indices, suppressed the spleen indices and strongly elevated the production of HSPCs, neutrophils and B cells in bone marrow, ameliorated bone marrow cellularity, and regulated the ratio of peripheral blood cells. Proteome profiling combined with ELISA revealed that CSEI regulated the levels of cytokines, especially G-CSF and its related factors, in the spleen and plasma. Additional data revealed that CSEI promoted phosphorylation of STAT3, which was stimulated by G-CSF in both mice spleen and cultured BMNCs. Taken together, CSEI has the potential to improve hematopoietic function via the G-CSF-mediated JAK2/STAT3 signaling pathway.
Membrane fouling induced by AHL-mediated soluble microbial product (SMP) formation by fouling-causing bacteria co-cultured with fouling-enhancing bacteria
Authors: Ishizaki So , Sugiyama Ryoichi , Okabe Satoshi 
Published: August 2017

AbstractMembrane fouling still remains a major obstacle for wider applications of membrane bioreactor (MBR), which is mainly caused by soluble microbial products (SMP). Identification of key bacteria responsible for SMP production is essential for mitigation of membrane fouling. Here, we investigated the effect of microbial interaction on membrane fouling. We measured the membrane fouling potentials of 13 bacterial strains isolated from a pilot-scale MBR treating domestic wastewater when they were cultivated as single-culture and co-culture. We found that fouling-causing bacteria (FCB) displayed much higher fouling potential when co-cultured even with non-FCB and mixed population (activated sludge). In particular, the fouling potential of strain S26, one of FCB, increased 26.8 times when cultivated with strain S22 (fouling-enhancing bacteria, FEB). The secretion of N-octanoyl-L-homoserine lactone (C8-HSL) was increased by co-cultivating S22 and S26 as compared with cultivating as single culture, which stimulated the production of fouling-causing SMP by S26 and consequently resulted in severe membrane fouling. This result suggests that AHL-mediated quorum-sensing (QS) regulatory system was involved in secretion of fouling-causing SMP.
Comparison of chronic physical and emotional social defeat stress effects on mesocorticolimbic circuit activation and voluntary consumption of morphine
Authors: Cooper S. E. , Kechner M. , Caraballo-Pérez D. , Kaska S. , Robison A. J. , Mazei-Robison M. S. 
Published: August 2017

AbstractChronic social defeat stress (CSDS) is a well-established rodent model of depression that induces persistent social avoidance. CSDS triggers molecular adaptations throughout the mesocorticolimbic reward circuit, including changes in the activity of dopamine neurons in the ventral tegmental area (VTA), that may also influence drug reward. One limitation of traditional, physical CSDS (PS) is that injury complicates the study of opiate drugs like morphine. Thus, we sought to characterize a variation of CSDS, termed emotional CSDS (ES), that eliminates this confound. We assessed the effect of PS and ES on mesocorticolimbic circuit activation, VTA gene expression, and morphine intake. We found that PS and ES similarly induced ΔFosB in the hippocampus, but only PS significantly increased ΔFosB expression in the prefrontal cortex and striatum. In contrast, cFos expression was similarly reduced by both PS and ES. Interestingly, we found that PS and ES similarly increased voluntary morphine consumption immediately following stress, despite differences in the magnitude of the depressive phenotype and striatal ΔFosB expression at this time point. Combined, these data suggest that both stress paradigms may be useful for investigation of stress-induced changes in drug behavior.
Sozialmedizin für Nicht-Sozialmediziner
Authors: Bahemann Andreas 
Published: August 2017

ZusammenfassungNicht nur Sozialmediziner benötigen Kenntnisse zu deren Aufgaben, Inhalten von Sozialmedizin, sozialrechtlichen Grundlagen und Begriffen aus der Begutachtung. Mit konkreten Beispielen wird ein Überblick gegeben.
Atlantoaxial Fusion Using C1 Sublaminar Cables and C2 Translaminar Screws
Authors: Larsen Alexandra M Giantini , Grannan Benjamin L , Koffie Robert M , Coumans Jean-Valéry 
Published: August 2017

Abstract

BACKGROUND
Atlantoaxial instability, which can arise in the setting of trauma, degenerative diseases, and neoplasm, is often managed surgically with C1–C2 arthrodesis. Classical C1–C2 fusion techniques require placement of instrumentation in close proximity to the vertebral artery and C2 nerve root.

OBJECTIVE
To report a novel C1–C2 fusion technique that utilizes C2 translaminar screws and C1 sublaminar cables to decrease the risk of injury to the vertebral artery and C2 nerve root.

METHODS
To facilitate fixation to the atlas, while minimizing the risk of injury to the vertebral artery and to the C2 nerve root, we sought to determine the feasibility of using a soft cable around the C1 arch and affixing it to a rod connected to C2 laminar screws. We reviewed our experience in 3 patients.

RESULTS
We used this technique in patients in whom we anticipated difficult C1 screw placement. Three patients were identified through a review of the senior author's cases. Atlantoaxial instability was associated with trauma in 2 patients and chronic degenerative changes in 1 patient. Common symptoms on presentation included pain and limited range of motion. All patients underwent C1–C2 fusion with C2 translaminar screws with sublaminar cable harnessing of the posterior arch of C1. There were no reports of postoperative complications or hardware failure.

CONCLUSION
We demonstrate a novel, technically straightforward approach for C1–C2 fusion that minimizes risk to the vertebral artery and to the C2 nerve root, while still allowing for semirigid fixation in instances of both traumatic and chronic degenerative atlantoaxial instability.
Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching*
Authors: Trauer James , Muhi Stephen , McBryde Emma S. , Al Harbi Shmeylan A. , Arabi Yaseen M. , Boyle Andrew J. , Cartin-Ceba Rodrigo , Chen Wei , Chen Yung-Tai , Falcone Marco , Gajic Ognjen , Godsell Jack , Gong Michelle Ng , Kor Daryl , Lösche Wolfgang , McAuley Daniel F. , O’Neal Hollis R. , Osthoff Michael , Otto Gordon P. , Sossdorf Maik , Tsai Min-Juei , Valerio-Rojas Juan C. , van der Poll Tom , Violi Francesco , Ware Lorraine , Widmer Andreas F. , Wiewel Maryse A. , Winning Johannes , Eisen Damon P. 
Published: August 2017

Objective:
The primary objective was to conduct a meta-analysis on published observational cohort data describing the association between acetyl-salicylic acid (aspirin) use prior to the onset of sepsis and mortality in hospitalized patients.

Study Selection:
Studies that reported mortality in patients on aspirin with sepsis with a comparison group of patients with sepsis not on prior aspirin therapy were included.

Data Sources:
Fifteen studies described hospital-based cohorts (n = 17,065), whereas one was a large insurance-based database (n = 683,421). Individual-level patient data were incorporated from all selected studies.

Data Extraction:
Propensity analyses with 1:1 propensity score matching at the study level were performed, using the most consistently available covariates judged to be associated with aspirin. Meta-analyses were performed to estimate the pooled average treatment effect of aspirin on sepsis-related mortality.

Data Synthesis:
Use of aspirin was associated with a 7% (95% CI, 2–12%; p = 0.005) reduction in the risk of death as shown by meta-analysis with considerable statistical heterogeneity (I
2 = 61.6%).

Conclusions:
These results are consistent with effects ranging from a 2% to 12% reduction in mortality risk in patients taking aspirin prior to sepsis onset. This association anticipates results of definitive studies of the use of low-dose aspirin as a strategy for reduction of deaths in patients with sepsis.