bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Enantio‐ and Diastereoselective Synthesis of γ‐Amino Alcohols.
Authors: Verkade Jorge M. M. , Quaedflieg Peter J. L. M. , Verzijl Gerard K. M. , Lefort Laurent , van Delft Floris L. , de Vries Johannes G. , Rutjes Floris P. J. T. 
Published: December 2015

AbstractIr‐catalyzed asymmetric transfer hydrogenation of β‐amino ketones leads to the corresponding N‐protected anti‐γ‐amino alcohols, while Rh‐catalyzed asymmetric hydrogenation affords the syn‐products.
ChemInform Abstract: Rhodium‐Catalyzed Alkoxylation/Acetalization of Diazo Compounds: One‐Step Synthesis of Highly Functionalized Quaternary Carbon Centers.
Authors: Pospech Jola , Lennox Alastair J. J. , Beller Matthias 
Published: December 2015

AbstractTrimethyl orthoformate is utilized as a C1‐building block in the tandem alkoxylation/acetalization of donor—acceptor‐substituted diazo compounds yielding α‐alkoxy β‐oxo esters.
ChemInform Abstract: Synthesis of New Phosphahelicene Scaffolds and Development of Gold(I)‐Catalyzed Enantioselective Allenene Cyclizations.
Authors: Aillard Paul , Retailleau Pascal , Voituriez Arnaud , Marinetti Angela 
Published: December 2015

AbstractFour new gold complexes containing a phosphahelicene scaffold are prepared and endo‐(P)‐(I) is found to be the most efficient one.
ChemInform Abstract: Computational and Experimental Studies of Phthaloyl Peroxide‐Mediated Hydroxylation of Arenes Yield a More Reactive Derivative, 4,5‐Dichlorophthaloyl Peroxide.
Authors: Camelio Andrew M. , Liang Yong , Eliasen Anders M. , Johnson Trevor C. , Yuan Changxia , Schuppe Alex W. , Houk K. N. , Siegel Dionicio 
Published: December 2015

AbstractDichlorophthaloyl peroxide is established as efficient reagent for hydroxylation of arenes.
ChemInform Abstract: Synthesis of o‐Carboxyarylacrylic Acids by Room Temperature Oxidative Cleavage of Hydroxynaphthalenes and Higher Aromatics with Oxone.
Authors: Parida Keshaba Nanda , Moorthy Jarugu Narasimha 
Published: December 2015

AbstractThe oxidation of hydroxy substituted polyarenes with Oxone is investigated resulting mainly in the formation of o‐carboxyarylacryl acids.
ChemInform Abstract: Palladium‐Catalyzed Domino Synthesis of 4‐Amino‐3‐acyl‐2‐naphthols via Isocyanide Chemoselective Insertion.
Authors: Chen Zhong , Duan Hua‐Qing , Jiang Xiao , Zhu Yong‐Ming , Ji Shun‐Jun , Yang Shi‐Lin 
Published: December 2015

AbstractThis novel strategy for preparation of the sterically hindered title compounds involves chemoselective isocyanide insertion followed by domino isomerization.
ChemInform Abstract: N‐Heterocyclic Carbene—Palladium(II)‐1‐methylimidazole Complex Catalyzed α‐Arylation Reactions of Tetralones with Aryl Chlorides and Further Transformation of the Products.
Authors: Yin Hui‐Ying , Lin Xia‐Li , Li Shu‐Wan , Shao Li‐Xiong 
Published: December 2015

AbstractThe outcome of the further transformation of tetralones is influenced by the steric hindrance of the aryl.
ChemInform Abstract: Synthesis of Benzofulvene Derivatives from Diarylacetylenes via Pd(II)‐Catalyzed Alkyne‐Directed C(sp2)—H Bond Activation.
Authors: Guo Biao , Zheng Liyao , Zhang Lei , Hua Ruimao 
Published: December 2015

AbstractThe synthesis of benzofulvenes from diarylacetylenes proceeds through a rarely reported carboxylate‐assisted alkyne‐directed ortho‐C(sp2)—H palladation followed by insertion of a second diarylacetylene.
ChemInform Abstract: Construction of Spirocycles Containing Highly Substituted Pyrroli‐dine and 1‐Indanone Motifs with Spiro Quaternary Stereogenic Centers via 1,3‐Dipolar Cycloaddition of 2‐Alkylidene‐1‐indanone and Azomethine Ylides Promoted by Simple Imidazolium Salts.
Authors: Hu Wei‐Qiang , Cui Yan‐Su , Wu Zhi‐Jun , Zhang Chuan‐Bao , Dou Pei‐Hao , Niu Song‐Yang , Fu Ji‐Ya , Liu Yong 
Published: December 2015

AbstractThe catalyst can be recycled and reused up to five times without significant loss of activity.
ChemInform Abstract: Copper‐Catalyzed Intramolecular Dehydrogenative Amidation of Unactivated C(sp3)—H Bonds Using O2 as the Sole Oxidant.
Authors: Wang Chunxia , Yang Yudong , Qin Dekun , He Zhen , You Jingsong 
Published: December 2015

AbstractThe title process allows the synthesis of diverse β‐lactams.
ChemInform Abstract: Palladium‐Catalyzed Oxidative Cross‐Coupling of Conjugated Enynones with Organoboronic Acids.
Authors: Xia Ying , Ge Rui , Chen Li , Liu Zhen , Xiao Qing , Zhang Yan , Wang Jianbo 
Published: December 2015

AbstractThis novel Pd‐catalyzed cross‐coupling reaction employs conjugated enynones as carbene precursors, providing functionalized furan derivatives including 2‐alkenylfurans and furan‐substituted 1,3‐dienes.
ChemInform Abstract: Mild Approach to 2‐Acylfurans via Intercepted Meyer—Schuster Rearrangement of 6‐Hydroxyhex‐2‐en‐4‐ynals.
Authors: Tharra Prabhakararao , Baire Beeraiah 
Published: December 2015

AbstractThe protocol includes addition of 2 nucleophiles during the Meyer—Schuster rearrangement and allows the preparation of a broad spectrum of furan structures, anellated with an alicyclic ring.
ChemInform Abstract: Transition‐Metal‐Free Synthesis of 2‐Substituted Methyl Benzo[b]furan‐3‐carboxylates.
Authors: Kang Byungsoo , Lee Min Hyung , Kim Mijung , Hwang Jungwoon , Kim Hyeong Baik , Chi Dae Yoon 
Published: December 2015

AbstractInvestigation of a suitable access to the cyclization precursors (III) and (VII) shows that EDC·HCl is an optimal agent which allows the isolation of the pure products by simple filtration.
ChemInform Abstract: Construction of Benzo[c]carbazoles and Their Antitumor Derivatives Through the Diels—Alder Reaction of 2‐Alkenylindoles and Arynes.
Authors: Sha Feng , Tao Yuan , Tang Chen‐Yu , Zhang Fei , Wu Xin‐Yan 
Published: December 2015

AbstractCompounds (XII) show promising antitumor activities.
ChemInform Abstract: Convenient Synthesis of 2‐Alkynylbenzazoles Through Sonogashira Cross‐Coupling Reaction Between Thioethers and Terminal Alkynes.
Authors: Paun Anca , Matache Mihaela , Enache Florina , Nicolau Ioana , Paraschivescu Codruta C. , Ionita Petre , Zarafu Irina , Parvulescu Vasile I. , Guillaumet Gerald 
Published: December 2015

AbstractThe coupling reaction proceeds under aerobic conditions with aromatic and aliphatic alkynes to give 2‐alkynyl substituted benzoxazoles and benzothiazoles.
ChemInform Abstract: External Oxidant‐Free Oxidative Cross‐Coupling: A Photoredox Cobalt‐Catalyzed Aromatic C—H Thiolation for Constructing C—S Bonds.
Authors: Zhang Guoting , Liu Chao , Yi Hong , Meng Qingyuan , Bian Changliang , Chen Hong , Jian Jing‐Xin , Wu Li‐Zhu , Lei Aiwen 
Published: December 2015

AbstractA variety of benzothiazoles is obtained by an intramolecular oxidative photocyclization of corresponding N‐arylthioamides.
ChemInform Abstract: Metal‐Free Cycloaddition to Synthesize Naphtho[2,3‐d][1,2,3]triazole‐4,9‐diones.
Authors: Chen Ping‐Fan , Kuo Kung‐Kai , Vandavasi Jaya Kishore , Boominathan Siva Senthil Kumar , Chen Chung‐Yu , Wang Jeh‐Jeng 
Published: December 2015

AbstractFor the first time, a metal‐free alcohol‐azide cycloaddition is presented.
ChemInform Abstract: An Efficient Three‐Component Synthesis of Coumarin‐3‐carbamides by Use of Ni—NiO Nanoparticles as Magnetically Separable Catalyst.
Authors: Sepay Nayim , Guha Chayan , Kool Arpan , Mallik Asok K. 
Published: December 2015

AbstractVarious title coumarins are obtained by efficient and eco‐friendly reaction of 2‐hydroxybenzaldehyde, aliphatic primary/secondary amines, and diethyl malonate using ethanol as green solvent.
ChemInform Abstract: Rh‐Catalyzed Construction of Quinolin‐2(1H)‐ones via C—H Bond Activation of Simple Anilines with CO and Alkynes.
Authors: Li Xinyao , Li Xinwei , Jiao Ning 
Published: December 2015

AbstractA novel procedure is elaborated for the synthesis of quinolin‐2(1H)‐ones (IV), (VI), and (VIII) by Rh‐catalyzed reaction of N‐alkylanilines with CO and symmetrical alkynes in the presence of Cu(O‐Ac)2 as an oxidant.
ChemInform Abstract: A Mild Carbon—Boron Bond Formation from Diaryliodonium Salts.
Authors: Miralles N. , Romero R. M. , Fernandez E. , Muniz K. 
Published: December 2015

AbstractThe catalyst‐free reaction of symmetrical diaryliodonium acetates (I) with bis(pinacolato)diboron gives rise to aryl(pinacolboronate) esters (III) in moderate to good yields.
ChemInform Abstract: A Catalytic SEAr Approach to Dibenzosiloles Functionalized at Both Benzene Cores.
Authors: Omann Lukas , Oestreich Martin 
Published: December 2015

AbstractA facile protocol is developed for the microwave assisted conversion of ortho‐silylated biphenyls into dibenzosiloles, including dichloro‐substituted derivatives (VI), which are relevant building blocks for the construction of π‐extended structures.
ChemInform Abstract: New Monoterpenoids from Fruits of Gardenia jasminoides var. radicans.
Authors: Yu Shao‐Fu , Huang Xiao‐Jun , Fu Shu‐Na , Wu Chun , Ye Wen‐Cai , Zhou Guang‐Xiong 
Published: December 2015

AbstractThe new lactone, cyclopentanepyrone A (I), and the two new monoterpenoids, gardeterpenone A (II) and jasminoside V (III), are isolated along with four known monoterpenoids.
ChemInform Abstract: Coupling‐Reagent‐Free Synthesis of Dipeptides and Tripeptides Using Amino Acid Ionic Liquids.
Authors: Furukawa Shinya , Fukuyama Takahide , Matsui Akihiro , Kuratsu Mai , Nakaya Ryotaro , Ineyama Takashi , Ueda Hiroshi , Ryu Ilhyong 
Published: December 2015

AbstractThe procedure is based on the reaction of HCl salts of amino acid methyl esters with 5.4 equiv.
ChemInform Abstract: Bioactive Alkaloids from the Red Sea Marine Verongid Sponge Pseudoceratina arabica
Authors: Shaala Lamiaa A. , Youssef Diaa T. A. , Badr Jihan M. , Sulaiman Mansour , Khedr Alaa , El Sayed Khalid A. 
Published: December 2015

Abstractisolation and structure elucidation of ceratinines F—H (I,II, and III)
ChemInform Abstract: Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta.
Authors: Gerwick William H. , et al.  
Published: December 2015

AbstractThe polyhydroxy macrolide (I), possessing a 40‐membered ring, is isolated from a new genus of the tropical title marine.
Recent Advances in Sensing Using Atropoisomeric Molecular Receptors
Authors: Pasini Dario , Nitti Andrea 
Published: December 2015

AbstractWe describe recent advances in chiroptical chemical sensors, in which the design and implementation is based upon the introduction of atropoisomerically chiral moiety within the molecular skeleton. This report include examples of acyclic, macrocyclic, and polymeric receptors that contain this motif. Although the main applications are in the enantioselective sensing of analytes, we report here some cases where the chiral receptors can in fact be used to senseachiral species. Using circular dichroism (CD) spectroscopy as the technique to detect a receptor–analyte interaction, we can distinguish two main sensor categories: that in which the CD signal of a stereolabile, CD‐silent probe is activated upon binding, and that in which the signal of a CD‐active probe is modulated upon binding. Particular emphasis will be given to cases in which CD spectroscopy is used orthogonally to other means of detection. Chirality 28:116–123, 2016. © 2015 Wiley Periodicals, Inc.
Edgeworth expansions for two‐stage sampling with applications to stratified and cluster sampling
Authors: Mirakhmedov Sherzod M. , Jammalamadaka Sreenivasa R. , Ekström Magnus 
Published: December 2015

AbstractA two‐term Edgeworth expansion for the standardized version of the sample total in a two‐stage sampling design is derived. In particular, for the commonly used stratified and cluster sampling schemes, formal two‐term asymptotic expansions are obtained for theStudentizedversions of the sample total. These results are applied in conjunction with the bootstrap to construct more accurate confidence intervals for the unknown population total in such sampling schemes.The Canadian Journal of Statistics43: 578–599; 2015 © 2015 The Authors. The Canadian Journal of Statistics published by Wiley Periodicals, Inc. on behalf of Statistical Society of Canada
Working after a metastatic cancer diagnosis: Factors affecting employment in the metastatic setting from ECOG‐ACRIN's Symptom Outcomes and Practice Patterns study
Authors: Tevaarwerk Amye J. , Lee Ju‐Whei , Terhaar Abigail , Sesto Mary E. , Smith Mary Lou , Cleeland Charles S. , Fisch Michael J. 
Published: December 2015

BACKGROUNDImproved survival for individuals with metastatic cancer accentuates the importance of employment for cancer survivors. A better understanding of how metastatic cancer affects employment is a necessary step toward the development of tools for assisting survivors in this important realm.METHODSThe ECOG‐ACRIN Symptom Outcomes and Practice Patterns study was analyzed to investigate what factors were associated with the employment of 680 metastatic cancer patients. Univariate and multivariate logistic regression analyses were conducted to compare patients stably working with patients no longer working.RESULTSThere were 668 metastatic working‐age participants in the analysis: 236 (35%) worked full‐ or part‐time, whereas 302 (45%) had stopped working because of illness. Overall, 58% reported some change in employment due to illness. A better performance status and non‐Hispanic white ethnicity/race were significantly associated with continuing to work despite a metastatic cancer diagnosis in the multivariate analysis. The disease type, time since metastatic diagnosis, number of metastatic sites, location of metastatic disease, and treatment status had no significant impact. Among the potentially modifiable factors, receiving hormonal treatment (if a viable option) and decreasing symptom interference were associated with continuing to work.CONCLUSIONSA significant percentage of the metastatic patients remained employed; increased symptom burden was associated with a change to no longer working. Modifiable factors resulting in work interference should be minimized so that patients with metastatic disease may continue working if this is desired. Improvements in symptom control and strategies developed to help address workplace difficulties have promise for improving this aspect of survivorship. Cancer 2016;122:438–446. © 2015 American Cancer Society.
Young investigator challenge: Comparison of 2 different methods of manual slide screening in semiautomated gynecologic cytology
Authors: Vaickus Louis J. , Wilbur David C. , Sweeney Brenda J. , Renshaw Andrew A. 
Published: December 2015

BACKGROUNDNegative gynecologic cytology cases (ie, those diagnosed as negative for intraepithelial lesion or malignancy) are manually reviewed by 2 methods using semiautomated screening: 1) immediate full slide review (FSR) after fields‐of‐view analysis (FOV) (FOV + FSR), and 2) quality‐assurance/high‐risk, quintile‐directed full manual review (FMR). Data supporting current guidelines were limited. The authors investigated FMR, FOV + FSR, and the review process in general.METHODSGynecologic cytology cases from 2009 to 2014 at Massachusetts General Hospital were analyzed. The data comprised 93,169 patients, 194,656 specimens, and 49,979 human papillomavirus (HPV) tests.RESULTSIn patients who underwent FMR, the epithelial cell abnormality (ECA) rate was correlated with the HPV‐positive rate (correlation coefficient [r2] = 0.82; Y = 0.19X + 0.02), and both rates decreased with age. For patients who underwent FOV + FSR, the ECA rate was also related to the HPV‐positive rate (r2 = 0.86; Y = 0.39X + 0.11), and both rates decreased with age. The FMR group had similar HPV‐positive rates compared to the FOV + FSR group (2%‐52% vs 9%‐68%, respectively). HPV‐positive patients had a higher risk of ECA than HPV‐negative patients (40% vs 8%; P < .0001). Currently, manual review allocates resources inefficiently, to older, HPV‐negative patients as compared to younger, HPV‐positive patients. Additionally, too many patients who have HPV‐positive specimens with ECA proceed from primary screening to FMR. This imbalance can be observed in the slope of the line comparing the FMR ECA rate with the HPV‐positive rate (which might serve as a surrogate marker for adequacy of FOV + FSR screening). Therefore, laboratories should try to reduce the number of HPV‐positive cases that reach FMR.CONCLUSIONSCurrent review procedures devote too few resources to younger patients. FMR should be assigned according to HPV status and age. The slope of the line comparing the FMR ECA rate with the FMR HPV‐positive rate might be a useful surrogate marker of screening accuracy. Cancer (Cancer Cytopathol) 2015;123:650–658. © 2015 American Cancer Society.
The Association among Childhood Trauma, Pathological Dissociation and Gambling Severity in Casino Gamblers
Authors: Imperatori Claudio , Innamorati Marco , Bersani Francesco Saverio , Imbimbo Francesca , Pompili Maurizio , Contardi Anna , Farina Benedetto 
Published: December 2015

The aim of the present study was to explore the role of pathological dissociation in mediating the association between childhood trauma (CT) and gambling severity. One hundred seventy‐one (134 men and 37 women) gamblers recruited in gambling environments (i.e., two Italian casinos) have been enrolled in the study. Psychopathological assessments included the Childhood Trauma Questionnaire (CTQ), the Dissociative Experiences Scale‐Taxon (DES‐T), the South Oaks Gambling Screen (SOGS), the CAGE and the Hospital Anxiety and Depression Scale. A mediational model, analyzing the direct and indirect effects of CTQ on SOGS through the mediating role of DES‐T, showed that the relation between CTQ and SOGS was fully mediated by DES‐T scores (b = 0.07; se = 0.15; p < 0.001). This finding raises the possibility that CT explains gambling severity through the presence of pathological dissociative symptoms and dissociative pathogenetic processes. Copyright © 2015 John Wiley & Sons, Ltd.Key Practitioner Message

Gambling severity is associated with both childhood trauma and pathological dissociation in casino gamblers.
A mediational model shows that the effect of childhood trauma on gambling severity is entirely mediated by pathological dissociation.
From a clinical point of view, our results highlight the importance of assessing, and possibly treating, dissociative symptoms in individuals with gambling disorder.
The connection Between Plasma Protein Binding and Acute Toxicity as Determined by the LD50 Value
Authors: Svennebring Andreas 
Published: December 2015

ABSTRACT

Preclinical Research

A dataset of three drug classes (acids, bases, and neutrals) with LD50 values in mice was analysed to investigate a possible connection between high plasma protein binding and acute toxicity. Initially, it was found that high plasma protein binding was associated with toxicity for acids and neutrals, but after compensating for differences in lipophilicity, plasma protein binding was found not to be associated with toxicity. The therapeutic index established by the quotient between mouse LD50 and the defined daily dose was unaffected by both lipophilicity and plasma protein binding. Drug Dev Res 77 : 3–11, 2016. © 2015 Wiley Periodicals, Inc.
Hot topics on diabetes in China
Authors: Weng Jianping , Pozzilli Paolo 
Published: December 2015

AbstractChina is the country with the largest burden of diabetes worldwide. Action is now taking place at different levels by the Chinese Diabetes Society, which has a major role in coordinating multi‐level activities across the country. These include, among others, the implementation of local guidelines for therapy, campaigns for education, trials for type 2 diabetes prevention and the establishment of extensive international collaborations in basic as well as clinical research. In this Special Issue, we briefly report on such initiatives, among which is a scientifically sound approach to exploring Chinese traditional medicine as a therapeutic option for diabetes treatment. Copyright © 2015 John Wiley & Sons, Ltd.
Chronic hypoxia down‐regulates tight junction protein ZO‐2 expression in children with cyanotic congenital heart defect
Authors: Jenkins Emma L. , Caputo Massimo , Angelini Gianni D. , Ghorbel Mohamed T. 
Published: December 2015

AbstractAimsTight junction protein zonula occludens protein 2 (ZO‐2) is a member of the membrane‐associated guanylate kinases protein family known to be expressed at tight junctions of epithelial and endothelial cells and at adherens junctions (AJs) in cardiomyocytes. Little is known about ZO‐2 expression and function in the human heart. Here, we examined the hypothesis that chronic hypoxia down‐regulates ZO‐2 expression in human myocardium and cultured rat cardiomyocytes.Methods and resultsPatients with a diagnosis of cyanotic (n = 10) or acyanotic (n = 10) Tetralogy of Fallot undergoing surgical repair were used to examine ZO‐2 messenger RNA and protein expression by real time‐PCR, immunohistochemistry, and western blotting. A model of cultured rat cardiomyocytes was used to measure ZO‐2 and AJ proteins levels in response to hypoxia and to investigate ZO‐2 cellular localization. We showed that ZO‐2 is expressed in myocardial tissue in acyanotic and cyanotic children with congenital heart defects. ZO‐2 was specifically down‐regulated in cyanotic myocardium at both the messenger RNA and protein levels when compared with acyanotic patients. This specific down‐regulation can be mimicked in cultured rat cardiomyocytes by treating them with hypoxic conditions confirming that ZO‐2 gene down‐regulation is specifically due to cyanosis. Furthermore, in addition to its cytoplasmic expression, ZO‐2 showed nuclear expression in cultured rat cardiomyocytes suggesting potential role in transcription regulation.ConclusionsHypoxia down‐regulates ZO‐2 expression in both cyanotic patient's myocardium and cultured rat cardiomyocytes. This down‐regulation suggest an involvement of ZO‐2 in cardiac remodelling of AJs in cyanotic children and may explain the greater susceptibility of cyanotic patients to corrective heart surgery.
Selenium‐Substituted Phosphaalk­enes Obtained through 1,2‐Elimination of Chlorosilanes from Selenen­ylchlorophosphines
Authors: Sasamori Takahiro , Villalba Franco José Manuel , Guo Jing‐Dong , Sugamata Koh , Nagase Shigeru , Streubel Rainer , Tokitoh Norihiro 
Published: December 2015

AbstractStable selenenyl‐chlorophosphines, bearing a silylalkyl group, were synthesized. Subsequent treatment with Lewis acids such as AlCl3 afforded the corresponding phosphaalkenes. A reaction mechanism that proceeds through an intramolecular 1,2‐elimination of chlorosilane was proposed.
Ni5.73InSe2– a Metal‐Rich Selenide Based on the Cu3Au‐Type 2D Het­erometallic Framework: Synthesis, Structure, and Bonding
Authors: Kuznetsov Alexey N. , Serov Alexey A. 
Published: December 2015

AbstractA new metal‐rich nickel–indium selenide, Ni5.73InSe2, was synthesized by annealing a mixture of the elements with a 6:1:2 ratio at 650 °C for 7 days with subsequent cooling to room temperature. Its crystal structure was determined from single‐crystal diffraction data, and the composition confirmed by an EDS analysis. The compound crystallizes in the tetragonal system [I4/mmm,a= 3.6797(5) Å,c= 18.845(4) Å,Z= 2] and is isotypic with the Ni7–xMQ2phases (M = Si, Ge, Sn, Sb; Q = S, Se, Te). Its main structural units are indium‐centered [Ni12In] cuboctahedra of the Cu3Au type and [Ni4–xSe2] blocks of the Cu2Sb type, alternating along thecaxis. Electronic structure calculations on the DFT/FP‐LAPW level predict metallic properties and indicate a temperature‐independent paramagnetic behavior for the new compound, which is supported by the experimental measurements. The ELI‐D topological analysis shows the multi‐centered nature of the bonding in both the nickel–indium and nickel–selenium fragments. Ni5.73InSe2represents the first example of a quasi‐2D mixed nickel–group 13 metal chalcogenide featuring [Ni12M] cuboctahedra of the Cu3Au type.