bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of preoperative and postoperative results of “canalicular triangular flap” and “triangular three-snip” punctoplasty techniques in patients with punctum stenosis using anterior segment optical coherence tomography
Authors: Turkoglu Elif H L , Comez Arzu T , Demir Mustafa 
Published: September 2024

Abstract

Purpose:
To compare the results and success rates of patients with epiphora due to punctal stenosis operated with the “canalicular triangular flap punctoplasty” and the “triangular three -snip punctoplasty” using anterior segment optical coherence tomography (AS-OCT).

Methods:
This study is a retrospective cohort analysis of patients who were diagnosed with punctal stenosis and underwent canalicular triangular flap or triangular three-snip punctoplasty between September 2021 and June 2022.

Results:
The study included 80 eyes of 43 patients consisting of 15 males and 28 females. Forty eyes underwent canalicular triangular flap punctoplasty (Group A) and 40 eyes underwent triangular three-snip punctoplasty (Group B) technique. The mean age of the patients was 63.9 ± 10.9 years (37–88 years). In Group A, the anatomic success was 100% and functional success was 95% at 6 months.In Group B, 77.5% functional success and 75% anatomic success were achieved at 6 months.

Conclusions:
The canalicular triangular flap technique was more successful in providing punctal patency both anatomically and functionally than the triangular three-snip punctoplasty. AS-OCT is a method that provides objective, quantitative results in the diagnosis and follow-up of punctal stenosis and may be used more widely in punctum and vertical canaliculi pathologies.
Reading eye movements among homonymous hemianopia
Authors: Gupta Nayan , Atiya Ayisha , Hussaindeen Jameel R , Ambika Selvakumar V 
Published: September 2024

Abstract

Purpose:
To measure the reading eye movement’s parameters and quantify the oculomotor dysfunction among subjects with homonymous hemianopia compared to age-matched controls using ReadAlyzer.

Methods:
This was a prospective study carried out in the neuro-optometry clinic of a tertiary eye care hospital in South India, from October 2018 to Janurary 2019. Fifty consecutive patients diagnosed with homonymous hemianopia were enrolled in the study after obtaining their written informed consent. Reading eye movements were measured using ReadAlyzer in patients with homonymous hemianopia and age-matched controls. Reading eye movement parameters were represented in median [interquartile range (IQR)].

Results:
Subjects with homonymous hemianopia showed increased number of fixations/100 words- median (IQR) [175 (80–270)] compared to controls [91 (52.5–127.5)]; increased number of regressions/100 words [33 (-13–79)] compared to controls [18 (-10–46)]; and reduced reading rate [93 (46–140) words/min] compared to controls [186 (144–228) words/min] (Mann–Whitney U test, P ≤ 0.05). Similar trend was observed for grade level equivalent 2 (0–4) and regression to fixation ratio 15 (1–29) compared to controls [grade equivalent 7 (3–11) and regression to fixation ratio 11 (-2–24)] (Mann–Whitney U test, P ≤ 0.005).

Conclusion:
Reading eye movements assessed using ReadAlyzer are found to be significantly impaired among homonymous hemianopias compared to age-matched controls (Mann–Whitney U test, P ≤ 0.05).
Corneal biomechanics in patients with allergic conjunctivitis
Authors: Wan Abdul Halim Wan Haslina , Jamaludin Mohd Ihsan , Cheng Teck Chee 
Published: September 2024

Abstract
Allergic conjunctivitis (AC) comprises a group of conditions triggered by environmental allergens, substantially diminishing the quality of life, particularly among children and adolescents. The mechanical impact of eye rubbing in patients with AC is known to induce biomechanical alterations in the cornea. Modern instruments enable the detection and quantification of these corneal biomechanical changes. The ocular response analyzer and CorVis ST have become standard tools for assessing corneal biomechanical properties. We conducted a review of studies that have investigated corneal biomechanics in patients with AC using both devices to elucidate the association between corneal biomechanical changes and early ectasia development. Our analysis highlights significant findings regarding the tomographic biomechanical index parameter in corneal biomechanics among patients with AC. These findings underscore the importance of ocular screening for all patients to promptly detect subclinical keratoconus changes, thereby improving disease management and outcomes.
How do young adults deal with suicidal ideation? A qualitative study of the experiences of stakeholders
Authors: Nair Vasundharaa S. , Joseph Miriyam , Ealias Neslin M. , Mohan Sharanya , Sreedaran Priya 
Published: September 2024

Background:
Persistent suicidal ideation, self-harm behaviors, and suicide attempts constitute suicidality and are consistent predictors for future suicides. Research on what protects individuals from harming themselves is equivocal. While factors like impulsivity could increase risk of suicide, research is needed on what stops people from acting out on self-harm thoughts/suicidal ideation.

Aim:
To explore the help-seeking behaviors and other protective factors during periods of suicidality in individuals at risk of suicide.

Method:
This study aimed to explore help-seeking behavior and other protective factors that prevent or delay self-harm and suicide attempts during suicidality in individuals at risk. We used a qualitative study design and interviewed 15 participants comprising at-risk individuals, caregivers, and mental health professionals (MHPs). We used thematic analysis for deriving themes.

Results:
Themes in ‘at-risk individuals’ include mental state during suicidality, handling of oneself during suicidality, and seeking help from support systems. Themes from caregivers included handling of crises and the role of informal and formal support systems. Themes from MHPs included phenomenology of suicidality, handling of suicidality, help-seeking, and support systems.

Conclusion:
At-risk individuals handle suicidality by either managing themselves on their own or seeking help from informal sources and formal health systems. Caregivers appear to be crucial stakeholders in help-seeking during self-harm. The involvement of caregivers – in discussion with the at-risk individual – should be a necessary component of suicide risk management. Suicide prevention policies at institutional, regional, and national levels should include strategies to prevent burnout and other occupational health issues in MHPs.
A comparative study on hair cortisol concentration among generalized anxiety disorder patients with and without alcohol dependence syndrome presenting to a tertiary care center: A pilot study
Authors: Bijjal Somashekhar , Huchegowda Ravish , Gowda Srinivas H. , Harbishettar Vijaykumar , Deshpande Srinivas R. , Sharma Manoj K. , Raju G M 
Published: September 2024

Background:
Generalized anxiety disorder (GAD) affects up to 6% of the population, which if not detected early and adequately treated will continue as a hidden impairment resulting in disability.

Aim:
The primary objective of the study is to assess the hair cortisol levels (HairF) in persons with GAD with and without alcohol dependence syndrome (ADS), and the secondary objective is to assess whether HairF can be used as a biomarker for assessment of GAD.

Materials and Methods:
This comparative study was done on 94 subjects (68 persons with GAD with or without ADS and 26 healthy controls) who were divided into three groups. Hamilton Anxiety Rating Scale (HAM-A) and Patient Health Questionnaire-4 (PHQ4) were also used to assess severity of anxiety symptoms. These scores were compared with HairF. Diagnostic accuracy of the HairF analysis test was done. Statistical analysis was done using SPSS version 20.

Results:
The study found higher levels of HairF in persons with GAD (mean 189.4 ± 33.1) and GAD with ADS (164.2 ± 47.6) compared to healthy controls (mean 45.34 ± 40.7), which were statistically significant. Correlation of HAM-A and PHQ4 scores and HairF also showed positive correlation. The receiver operating characteristic curve suggested the best cutoff point at 88.4 pg/mg with a sensitivity of 98.5% and a specificity of 92.5%, clearly differentiating GAD from healthy controls.

Conclusion:
HairF were found to be higher in patients with GAD irrespective of ADS as comorbidity. The study supports the possibility of the HairF as a possible biomarker to detect GAD and play a complementary role in a multidimensional approach for management of chronic stress and anxiety.
Focus group discussion with the medical interns regarding psychiatry posting
Authors: Deshpande Sharmishtha , Agawane Shubhangi , Zachariah Aaron , Innamuri Raviteja , Menon Vikas 
Published: September 2024

Background:
Medical interns have 2 weeks compulsory internship in psychiatry.

Aim:
We tried to explore their learning and views about psychiatry during these 2 weeks. To document verbatim their account about the knowledge gained and their experiences during the psychiatry internship posting and derive prominent themes.

Methods:
Focus group discussion was conducted at the end of the posting using a semistructured questionnaire for seven consecutive batches of interns posted in psychiatry. To enhance trustworthiness, we utilized member checking, data triangulation, and peer debriefing. Their routine during posting, competencies, expectations from the posting, and frustrations were the main points discussed. The interns willingly participated and discussed their views about psychiatry posting.

Results:
They were aware of psychiatry as an important medical discipline and had a fair degree of knowledge about it. Most of them found the posting useful. The interns had not attained the required competencies in handling emergencies and use of psychiatric drugs.

Conclusion:
Involvement of senior faculty and formative assessments will be necessary in the training of medical interns. This can ensure that they gain the required competencies.
Immersive Simulation Technologies as a Tool for Effective Medical Training
Authors: Danilina N. , Chekh V. 
Published: September 2024

The article discusses the features of using immersive simulation technologies in V. Soldatov Tobolsk Medical College in the process of training medical students. The emergence of complex medical equipment and technologies, changes in moral and legal conditions have become one of the reasons for the modernization of the system of medical training of a specialist.
ANALISA KINERJA LALU LINTAS JALAN KALIURANG (STUDI KASUS : JALAN KALIURANG KM 5,8 – 9,3 , KABUPATEN SLEMAN, DAERAH ISTIMEWA YOGYAKARTA)
Authors: Subagyo Singgih , Suryanto Suryanto , Nefo Handriansyah Muhammad 
Published: September 2024

Jalan Kaliurang merupakan sebuah jalan utama yang terletak di Sebelah Utara Kota Yogyakarta dan dekat dengan tempat Menuju wisata seperti Wisata Merapi dan di kawasan ini terdapat beberapa bangunan hotel, Pertokoan , Kos-Kosan dan Kampus Sehingga banyak kendaraan yang melintas, keluar/masuk, dan parkir di ruas jalan, serta banyak aktivitas manusia disekitar ruas jalan tersebut. Metode Penelitian yang di gunakan dalam pengambilan data adalah observasi dan pencatatan secara langsung dilapangan. Untuk datan primer meliputi : data geometri jalan, data volume lalu lintas dan kecepatan lalu lintas. Sedangkan data sekuder meliputi studi literatur dan Pedoman Kapasitas Jalan Indonesia (PKJI 2023). Sebagai Dasar penyelesaian data yang di gunakan adalah volume lalu lintas, Hambatan samping, kapasitas jalan, Derajat kejenuhan, Kecepatan arus bebas dan kecepatan dan waktu tempuh yang terdapat pada Pedoman Kapasitas Jalan Indonesia (PKJI 2023). Dari hasil survei selama 5 hari dan di lakukan analisis pada hari minggu pagi maka di peroleh bahwa volume puncak sebesar 6570,5 Smp/Jam, Pada hari Jum’at dengan Frekuensi bobot Kejadian Kejadian 497,8. Analisis perhitungan Kapasitas jalan pada jam puncak yaitu 4.060,8 Smp/jam, serta nilai Derajat Kejenuhan sebesar 0,87.
Obtención de genotipos mejorados de café (Coffea arabica L.) para la zona sur de Manabí, Ecuador
Authors: Ortiz Baque Jackson , Gabriel Ortega Julio 
Published: September 2024

En Ecuador fueron seleccionados cultivares de café introducidos, pero no existen antecedentes de haberse desarrollado nuevos cultivares mediante mejora genética convencional. El objetivo de esta investigación fue obtener genotipos mejorados de café para la zona Sur de Manabí, para esto se utilizó las el banco de germoplasma de café de la Universidad Estatal de Manabí, ubicado en la Finca Andil, en la campaña 2021, donde se obtuvieron familias F1 híbridas utilizando nueve accesiones parentales (Acawa, Arara, Burbon amarillo, Catimor CIFC, Catuai amarillo, Catucai 25L, Catucai 785-15, Caturra roja y Geisha), que fueron recombinadas en diseño dialélico de Griffin, obteniéndose 1477 genotipos. En la misma Finca, en vivero en las campañas 2022 - 2023, los materiales fueron sembrados en un diseño experimental completamente aleatorio. Se determinó la aptitud combinatoria general (ACG) y la aptitud combinatoria específica (ACE) para altura de planta (ADP), diámetro de tallo (DDT), número de pares de hojas (NPH), área foliar (AF), la heterosis y la heterobeltiosis de los parentales y las progenies. Los resultados mostraron que el progenitor Típica fue sobresaliente y significativo para ADP. DDT y AF. La familia 021-105 fue sobresaliente para el ADP, NPH y AF. La ACG para ADP, DDT, NPH y AF de los progenitores fue buena. Hubo heterosis para ADP, DDT y AF, en las familias 021-101 y 021-104; y, heterobeltiosis para ADP en las familias 021-105, 021-106, 021-, 021-108 y 021-109; y, para AF en las familias 021-105 y 021-109. Se identificaron genotipos con potencial para ser futuros cultivares.
KEBIJAKAN HUKUM PENERAPAN RESTORATIF JUSTICE DALAM PENYELESAIAN TINDAK PIDANA NARKOTIKA BERDASARKAN PERATURAN KEPOLISIAN NEGARA REPUBLIK INDONESIA NOMOR 8 TAHUN 2021 TENTANG PENANGANAN TINDAK PIDANA BERDASARKAN KEADILAN RESTORATIF (Studi di Direktorat
Authors: Syahputra Andrian Eka , Mukidi Mukidi , Akhya Adil 
Published: September 2024

Restorative Justice adalah pergeseran pemidanaan dalam sistem peradilan pidana yang lebih mengutamakan keadilan bagi korban dan pelaku tindak pidana selain bisa juga dengan alternatif hukuman seperti kerja sosial dan lainnya. Metode penelitian yang digunakan adalah deskriftif analisis yang mengarah pada penelitian hukum yuridis normatif dan didukung data yuridis empiris yakni penelitian yang dilakukan dengan cara mengacu pada norma-norma hukum yaitu meneliti terhadap bahan pustaka atau bahan sekunder. Data sekunder dengan mengolah data dari bahan hukum primer, bahan hukum sekunder dan bahan hukum tersier. Kesimpulan dari tesis ini adalah penegakan hukum penyelesaian perkara tindak pidana narkotika dengan pendekatan restoratif Justice pada tahapan penyidikan di direktorat reserse narkoba Polda Sumut dalam perkara narkotika yang diselesaikan melalui keadilan restoratif pada tahun 2020-2021 belum ada sedangkan pada tahun 2022 sebanyak 4 perkara dari 233 perkara yang diselesaikan melalui keadilan restoratif. Kemudian pada tahun 2023 sampai bulan Juli sebanyak 12 perkara dari 96 perkara.Upaya penganggulangan dan penyembuhan para pecandu narkoba melalui rehabilitasi para pecandu di wilayah hukum Kepolisian Daerah Sumatera Utara adalah memberikan sosialisasi/penjelasan kepada orangtua atau wali dari pecandu tentang Undang-Undang Narkotika, Pengaturan tindak pidana penyalahgunaan narkotika berdasarkan kebijakan hukum restoratif dalam proses penyidikan diatur dalam Perkap Kapolri No. 8 Tahun 2021 Tentang Penanganan Tindak Pidana Berdasarkan Keadilan Restoratif.
Chinese Academic Journals on International Relations and Issues: From Formation to the Present State
Authors: Янь Лэй. 
Published: September 2024

В статье рассматриваются издающиеся в КНР современные научные издания по международным отношениям и проблемам, в частности журналы и вестники. Основное внимание уделяется описанию их появления в соответствующие периоды развития современного Китая. Их обзор дан в конкретно-историческом ключе, с учетом основных периодов развития Нового Китая, включающих первые годы развития КНР, время культурной революции, период реформ, открытости и “социализма с китайской спецификой”, а также время последних десятилетий. Специальное внимание обращено на то, что ряд соответствующих изданий были учреждены именно для удовлетворения стратегических потребностей государства и создания собственной системы знаний как результата вступления Китая в новую эпоху.
The article examines contemporary scholarly publications on international relations and issues published in the People's Republic of China, particularly journals and bulletins. The primary focus is on describing their emergence during respective periods of modern China's development. Their overview is presented through a concrete historical lens, taking into account main periods of New China's development, including the early years of the PRC's development, the time of the Cultural Revolution, the period of reform, opening up, and “socialism with Chinese characteristics,” as well as the recent decades. Special attention is drawn to the fact that a number of relevant publications were established specifically to meet the strategic needs of the state and create its own knowledge system as a result of China's entry into a new era.
Predictive value of the BDH2–MN2 nomogram model for prognosis at 3 months after receiving intravenous thrombolysis in patients with acute ischemic stroke
Authors: Li Ynglei , Li Ning , Xi Lingyun , Li Litao 
Published: September 2024

IntroductionThe present study focused on developing a nomogram model to predict the 3-month survival of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis with tissue plasminogen activator (tPA).Material and methodsA total of 709 patients were enrolled in the present study, including 496 patients in the training set and 213 patients in the validation set. All data were statistically analyzed using R software. We applied LASSO regression analysis to construct nomograms by screening statistically significant predictors from all variables.The model discrimination was evaluated based on the area under the receiver operating characteristic curve (AUC-ROC).ResultsLASSO regression analysis was conducted for all variables, which revealed BNP, DNT, HCY, HDL, MHR, NHR and post-thrombolysis NIHSS as independent predictors of adverse outcomes at 3 months after intravenous thrombolysis. Accordingly, these seven factors were incorporated in the nominated BDH2–MN2 nomogram. The resulting AUC-ROC values determined for the training and validation sets were 0.937 (95% CI: 0.822–0.954) and 0.898 (95% CI: 0.748–0.921), respectively.ConclusionsA robust BDH2–MN2 (BNP, DNT, HCY, HDL, MHR, NHR and post-thrombolysis NIHSS) nomogram model was successfully developed and validated. The developed nomogram enables prediction of adverse outcomes of individual AIS patients receiving intravenous thrombolysis with alteplase for 3 months.
Sanguiin inhibits cerebral hemorrhage in rats by protecting the blood-brain barrier
Authors: Zhang Liguo , Li Jing , Zhang Yisong , Zhang Hengzhu 
Published: September 2024

IntroductionThe aim of the study was to observe the effect of Sanguiin on cerebral edema and behavior in a rat cerebral hemorrhage model.Material and methodsA rat collagenase-induced cerebral hemorrhage model was established to detect the effects of drugs on brain edema.ResultsThrough magnetic resonance imaging (MRI) analysis and brain weight content (BWC) determination, it was found that Sanguiin could significantly reduce the brain swelling index and BWC of the affected hemisphere after cerebral hemorrhage.ConclusionsSanguiin can significantly improve the neurological deficits in rats with cerebral hemorrhage, and down-regulate the expression of MMP-9 after cerebral hemorrhage, suggesting that Sanguiin has a certain protective effect on the blood-brain barrier after cerebral hemorrhage.
Intolerance of uncertainty, curiosity, generalized anxiety disorder, and subjective happiness
in the time of earthquakes in Türkiye
Authors: Yılmaz Fatma Betül , Satıcı Seydi Ahmet , Okur Sinan , Kütük Hasan , Aktepe Zahide Gül 
Published: September 2024

BackgroundOn February 6, 2023, a devastating earthquake disaster occurred in Türkiye, affecting millions. Mental health concerns were high due to people’s exposure to loss and possible earthquakes. In these times, variables that predict individuals’ mental health should be determined. The aim of this study was to investigate the relationship between intolerance of uncertainty, curiosity, generalized anxiety disorder, and subjective happiness using structural equation modeling.Participants and procedureThe research was conducted on Turkish individuals in 29 different cities in Türkiye. For the purpose of the research, data were collected from 345 participants (79.7% females, 20.3% males, age range = 18-61, Mage = 26.73 years). One hundred eighty nine of the participants were single (54.7%), 77 were married (22.4%), and the remaining 79 were in a relationship or engaged (22.9%). Additionally, it was found that 52 of the participants were parents (15.1%). In terms of socio-economic status, the majority fell into the middle-class category (n = 263, 76.2%).ResultsIt was found that intolerance to uncertainty predicted subjective happiness, and generalized anxiety disorder mediated this relationship. In addition, curiosity predicted subjective happiness, and generalized anxiety disorder mediated this relation-ship.ConclusionsAll the findings obtained in the research revealed the mental health problems experienced by individuals after the earth-quake. This research on earthquakes and mental health makes important contributions to the field of psychology.
Prevalência de Cárie e fatores associados em crianças com dentição decídua em um município do interior de Minas Gerais
Authors: De Souza Queiroga Aline , Dos Santos Barbosa Sarah , Almeida Sausmikat Desirée , Moreira Reis Ranam , Cristina Gomes Janaína , Miluska Suca Salas Mabel 
Published: September 2024

O objetivo foi determinar a prevalência de cárie e os fatores associados de crianças pré-escolares. O presente estudo de tipo transversal, teve como população alvo crianças com dentição decídua entre 2 e 6 anos de duas creches municipais de Governador Valadares. Para formar parte da amostra os pais ou responsáveis assinaram um Termo de Consentimento Livre e Esclarecido (CEP nº 2.740.143). Dois examinadores foram treinados para o exame clinico utilizando o índice ceo-d. Um questionário baseado na literatura e previamente testado, incluiu informações sociodemográficas e comportamentais e foi aplicado nas mães. A análise estatística foi descritiva e inferencial bivariada usando teste de Qui-quadrado, Fisher e/ou de tendência linear. Participaram do estudo 97 crianças. A maioria das crianças eram do sexo feminino (53,6%), tinham 5 e 6 anos de idade (42,6%), cor de pele preta/parda (60.4%) e eram de famílias com renda inferior a 1 salário mínimo (56,5%). A experiência de cárie foi 26,6%. Dentes cariados foram observados em 24,1% das crianças. A maior prevalência de cárie esteve associada a idade e a overjet maxilar (p<0,0001). A prevalência de cárie e de dentes cariados na dentição decídua foi alta, estando associada à maior idade e overjet maxilar.