bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metis Observation of the Onset of Fully Developed Turbulence in the Solar Corona
Authors: Telloni Daniele , Sorriso-Valvo Luca , Zank Gary P. , Velli Marco , Andretta Vincenzo , Perrone Denise , Marino Raffaele , Carbone Francesco , Vecchio Antonio , Adhikari Laxman , Zhao Lingling , Guastavino Sabrina , Camattari Fabiana , Shi Chen , Sioulas Nikos , Huang Zesen , Romoli Marco , Antonucci Ester , Da Deppo Vania , Fineschi Silvano , Grimani Catia , Heinzel Petr , Moses John D. , Naletto Giampiero , Nicolini Gianalfredo , Spadaro Daniele , Stangalini Marco , Teriaca Luca , Uslenghi Michela , Abbo Lucia , Auchère Frédéric , Cuadrado Regina Aznar , Berlicki Arkadiusz , Bruno Roberto , Burtovoi Aleksandr , Capobianco Gerardo , Casini Chiara , Casti Marta , Chioetto Paolo , Corso Alain J. , D’Amicis Raffaella , De Leo Yara , Fabi Michele , Frassati Federica , Frassetto Fabio , Giordano Silvio , Guglielmino Salvo L. , Jerse Giovanna , Landini Federico , Liberatore Alessandro , Magli Enrico , Massone Giuseppe , Nisticò Giuseppe , Pancrazzi Maurizio , Pelizzo Maria G. , Peter Hardi , Plainaki Christina , Poletto Luca , Reale Fabio , Romano Paolo , Russano Giuliana , Sasso Clementina , Schühle Udo , Solanki Sami K. , Strachan Leonard , Straus Thomas , Susino Roberto , Ventura Rita , Volpicelli Cosimo A. , Woch Joachim , Zangrilli Luca , Zimbardo Gaetano , Zuppella Paola 
Published: September 2024

Abstract
This Letter reports the first observation of the onset of fully developed turbulence in the solar corona. Long time series of white-light coronal images, acquired by Metis aboard Solar Orbiter at 2 minutes cadence and spanning about 10 hr, were studied to gain insight into the statistical properties of fluctuations in the density of the coronal plasma in the time domain. From pixel-by-pixel spectral frequency analysis in the whole Metis field of view, the scaling exponents of plasma fluctuations were derived. The results show that, over timescales ranging from 1 to 10 hr and corresponding to the photospheric mesogranulation-driven dynamics, the density spectra become shallower moving away from the Sun, resembling a Kolmogorov-like spectrum at 3 R
⊙. According to the latest observation and interpretive work, the observed 5/3 scaling law for density fluctuations is indicative of the onset of fully developed turbulence in the corona. Metis observation-based evidence for a Kolmogorov turbulent form of the fluctuating density spectrum casts light on the evolution of 2D turbulence in the early stages of its upward transport from the low corona.
Du bidon à la pompe : la vente du pétrole en province et ses contestations (Côte-d’Or, 1877-1939)
Authors: Dhotel Timothée 
Published: September 2024

Cet article éclaire l’arrivée du pétrole en France, et plus particulièrement en Côte-d’Or. Alors que les premiers fûts sont importés en 1861 sur les côtes normandes, la première trace d’un dépôt de pétrole dans ce département rural organisé autour de la ville de Dijon n’apparaît pas avant 1877. Leur nombre s’élève à près de 960 en 1939. Cette croissance tirée par les usages lampants et plus encore par la demande de carburant liée à l’essor de l’automobile témoigne d’une « pétrolisation » qui pour être incontestable n’en a pas moins été contestée. Les conflits autour des demandes d’installation documentent une histoire sociale et environnementale du pétrole, que l’on peut ainsi écrire du point de vue des acteurs locaux (riverains et vendeurs), en prise avec les compagnies pétrolières et l’État.
An evaluation of support to the second victims in Tshwane District Health Services, South Africa
Authors: Nzaumvila Doudou K. , Bongongo Tombo , Govender Indiran , Okeke Sunday O. 
Published: September 2024

Background: Initiatives to reduce patient safety incidents (PSI) and support healthcare professionals who may experience psychological trauma as a result are becoming increasingly common. However, little is known about the quality of the support provided by Tshwane District Health Services. Therefore, it is necessary to assess their assistance for the second victims in order to evaluate their effectiveness.Methods: A cross-sectional study was conducted, and 319 healthcare professionals from six primary health care institutions were invited to participate in the study. The sociodemographic information, work experience, emotional support, familiarity with the concept of the ‘second victim’ and involvement with PSIs were collected.Results: The mean age was 39.8 years, ranging from 22 years to 66 years. The majority of participants were females (n = 249; 78.1%), nurses (n = 153; 49.2%), and those with 5–9 years of experience (n = 82; 25.8%). Most participants (n = 168; 52.7%) were aware of the possibilities of emotional support, while less than half (n = 142; 44.5%) were familiar with the term ‘second victim’. The cumulative incidence of adverse events in the institutions was 19.4%, and the majority of second victims (n = 39; 62.9%) emotionally felt the need to speak with someone about it, preferably outside of the workplace. Less than 5% of individuals received support that was initiated by existing structures at their workplace.Conclusion: Frameworks exist to assist second victims, although they are only known to some healthcare professionals. However, their current use in Tshwane health facilities is ineffective. After experiencing PSIs, second victims often rely on psychological assistance outside of the workplace.Contribution: Authorities need to determine the causes behind some healthcare professionals’ lack of awareness regarding the support framework for second victims, as well as their growing tendency to rely on psychologists outside of the workplace, and corrective measures should be implemented.
Lithium-induced cognitive dysfunction assessed over 1-year hospitalisation: A case report
Authors: Murase Yuji , Kato Masaki , Kinoshita Toshihiko , Takekita Yoshiteru 
Published: September 2024

Introduction: Lithium-induced neurotoxicity is almost always reversible but can cause irreversible neurological sequelae, namely the syndrome of irreversible lithium-effectuated neurotoxicity (SILENT). As there is no definitive treatment for SILENT, caution is required when administering lithium. Reports on the effect of lithium-effectuated neurotoxicity on cognitive function are limited. We report a case in which high cognitive function was lost after lithium overdose and hardly recovered, as evaluated using multiple neuropsychological tests during a 1-year hospitalisation period.Patient presentation: A 52-year-old man on lithium medication with bipolar disorder was admitted to the intensive care unit because of lithium overdose. The patient achieved lucid consciousness after continuous haemodiafiltration. However, he could not move his body as desired or produce appropriate verbal expressions; thus, he was moved to our psychiatric ward, where his treatment continued.Management and outcome: After several months, the patient was diagnosed with SILENT owing to persistent motor and cognitive dysfunctions. Multiple neuropsychological tests were performed, and cognitive function was evaluated. The Neurobehavioural Cognitive Status Examination showed a worsening trend, and the full intelligence quotient of the Wechsler Adult Intelligence Scale-Third Edition was in the mild intellectual disability range.Conclusion: This is a clear case of cognitive dysfunction due to SILENT and is difficult to treat. Thus, it is crucial to prevent the onset of SILENT.Contribution: This report is valuable because it is one of the few to track changes in cognitive function over time in a patient with SILENT using objective measures over 1 year of hospitalisation.
A Gamut of Astounding Diagnosis as Paraganglioma of Urinary Bladder: A Retrospective Study from North India
Authors: Walvir Nazia Manzoor , Aiman Aiffa , Abeer Inara , Lone Mohammad Iqbal , Maqsood Shadab 
Published: September 2024

Background and Aim:
Urinary bladder paraganglioma (UBPGL) is a rare neuroendocrine neoplasm, accounting for <0.05% of all bladder tumors and 0.7% of all paragangliomas. This study aimed to describe the histopathology of UBPGL, emphasizing the histologic attributes that may help pathologists recognize this rare bladder tumor and aid in differentiation from urothelial malignancies and other tumors that may resemble paragangliomas.

Materials and Methods:
This retrospective observational study was conducted in the pathology department of a tertiary care hospital in North India for 4 years between 2019 and 2022. The study included all cases diagnosed with UBPGL on histopathology and confirmed on immunohistochemistry.

Results:
Nine study cases were included in this study with a median age of 56 years. Most cases had a history of palpitations, hematuria, and hypertension. Tissue specimens for all the cases were obtained after transurethral resection of bladder tumors. Histologically, the zellballen pattern was present in seven (78.8%), and a diffuse growth pattern was present in two (22.2%) cases. Delicate fibrovascular stroma was pronounced in eight (88.9%) cases. Immunohistochemically, all nine tumors were positive for chromogranin A and eight were positive for synaptophysin. Muscularis propria invasion was seen in seven (78.8%) cases, a focal sheet-like pattern in one (11.1%), a ribbon-like growth pattern in one (11.1%), focal necrosis in three (33.3%), and associated significant cautery artifacts in four cases (44.5%).

Conclusions:
UBPGL is often misdiagnosed as urothelial cancer because of its frequent muscle invasion and similar morphology. Distinguishing paraganglioma from urothelial cancer is vital because of the difference in prognosis and surgical management. A conclusive diagnosis can be made with thorough histologic examination and immunohistochemical analysis.
Asiaticoside ameliorates type 2 diabetes mellitus in rats by modulating carbohydrate metabolism and regulating insulin signaling
Authors: Prathap B. , Satyanarayanan V. , Duraipandian K. , Subashree P. 
Published: September 2024

Objective:
To evaluate the effect of asiaticoside on streptozotocin (STZ) and nicotinamide (NAD)-induced carbohydrate metabolism abnormalities and deregulated insulin signaling pathways in rats.

Methods:
Asiaticoside (50 and 100 mg/kg body weight) was administered to STZ-NAD-induced diabetic rats for 45 days, and its effects on hyperglycaemic, carbohydrate metabolic, and insulin signaling pathway markers were examined.

Results:
Asiaticoside increased insulin production, lowered blood glucose levels, and enhanced glycolysis by improving hexokinase activity and suppressing glucose-6-phosphatase and fructose-1,6-bisphosphatase activities. Abnormalities in glycogen metabolism were mitigated by increasing glycogen synthase activity and gluconeogenesis was decreased by decreasing glycogen phosphorylase activity. Furthermore, asiaticoside upregulated the mRNA expressions of IRS-1, IRS-2, and GLUT4 in STZ-NAD-induced diabetic rats and restored the beta cell morphology to normal.

Conclusions:
Asiaticoside has the potential to ameliorate type 2 diabetes by improving glycolysis, gluconeogenesis, and insulin signaling pathways.
Symptomatic bradycardia in tuberculosis-related giant bullae (vanishing lung syndrome): A case report
Authors: Laysandro Reynard , Meha Jessie Julian Mila , Mulia Resley Ongga , Mikha  , Yusfiatuzzahra Nazamta 
Published: September 2024

Rationale:
Vanishing lung syndrome is rare and can be associated with a history of smoking and marijuana use. The occurrence of giant bullae can also be linked to infections, particularly tuberculosis in tropical countries.

Patient concerns:
A 26-year-old male complained of weakness, severe vomiting, and reduced breathlessness when lying on the left side. He had a history of pulmonary tuberculosis two years ago.

Diagnosis:
Symptomatic bradycardia in tuberculosis-related giant bullae.

Interventions:
The patient was recommended to undergo an elective bullectomy, but he decided not to proceed with the procedure. Atropine sulfate was administered to alleviate symptoms of bradycardia, while a standardized anti-tuberculosis regimen were started for the next six months.

Outcomes:
Following 7 days of intensive care treatment involving antituberculosis medications and atropine sulfate, the patient achieved hemodynamic stability, opting against bullectomy despite residual symptoms of dyspnea. Subsequent six months of antituberculosis therapy notably alleviated symptoms without requiring bullectomy.

Lessons:
Increasing intrathoracic pressure can also be caused mechanically by giant bullae. Cardiac symptoms in vanishing lung syndrome are reversible and can be alleviated once the underlying cause is addressed. In this case, symptomatic bradycardia was reduced only with tuberculosis treatment without bullectomy intervention.
Epidemiological observations of invasive group B Streptococcus infections in six major hospitals in Peninsular Malaysia
Authors: Muthanna AbdulRahman , Desa Mohd Nasir Mohd , Rahman Nurul Asyikin Abdul , Dzaraly Nurul Diana , Baharin Nurul Hana Zainal , Aziz Nur Afiza , Shan Chua Hui , Ismail Zalina , Nor Lailatul Akmar Mat , Ali Marlindawati Mohd , Ahmad Nur Hanani , Azmai Mohammad Noor Amal , Amin-Nordin Syafinaz 
Published: September 2024

Objective:
To address the lack of research on invasive group B Streptococcus (GBS) infections in Malaysia and Southeast Asia through a comprehensive analysis of GBS isolates obtained from hospitals.

Methods:
Medical records from patients with GBS infection isolated from the sterile site, such as blood and cerebrospinal fluid from 14 July 2019 to 15 December 2020, were reviewed from six major hospitals in Peninsular Malaysia. Inclusion criteria were invasive GBS, sterile sites and non-repeated GBS isolated from the same patients in the same admission. Viable isolates were re-identified for GBS and serotyped.

Results:
A total of 118 patients were eligible, with a majority of non-pregnant adults (76.3%). Over half of the patients (62.7%) had underlying medical conditions, with diabetes as the most common disease, followed by respiratory disease, renal disease, cardiovascular disease and skin and soft tissue disease. The most common manifestations were sepsis, followed by soft tissue abscess, diabetic foot ulcer, wet gangrene and cellulitis. The overall mortality was 7.6%. The most common serotype was serotype V.

Conclusions:
Invasive GBS infection among non-pregnant adults showed a rising trend, particularly among diabetic individuals. The study underscores the importance of reducing risk factors and highlights the necessity of developing GBS vaccination as a preventive strategy for both infants and adults.
To Assess the Impact of the Quality and Level of Family Support to Pregnant Women on Maternal and Fetal Outcomes
Authors: Mane Ujwala R. , Salunkhe Jyoti A. , Kakade Satish V. 
Published: September 2024

Abstract

Background:
Throughout pregnancy, women need support from the family to gain better maternal and fetal outcomes. Emotional distress in women during pregnancy is known to increase the risk of adverse outcomes in women and newborns. Increasing family support can improve birth outcomes and maternal wellbeing and can reduce complications in mother and increased neonatal birth weight.

Aim and Objective:
This study aims to evaluate the influence of the level and quality of family support during pregnancy on maternal and fetal outcomes and to identify any association between sociodemographic variables and the impact of the level and quality of family support during the third trimester.

Materials and Methods:
This study used a quantitative approach combined with a survey research design. Data were collected from four primary health centers (Rethare, Vadgaon, Kale, and Supane) at Karad, Maharashtra, India. A consecutive sampling technique was used to select the 344 subjects from the Rethare, Vadgaon, Kale, and Supane areas of Karad Taluka. Data were collected before the completion of the first trimester, then during the second trimester, and post-delivery. Upon evaluation, the tool was validated by experts representing the fields of community health nursing, mental health nursing, obstetric gynecology, and pediatric care. A pilot study was conducted on 30 samples. The data collected were analyzed by using descriptive and inferential statistics.

Result:
Findings regarding level of family support show that 133 women (38.7%) received good total support, 164 (47.7%) received moderate support, and 47 (13.7%) received poor family support during the third trimester. Results regarding maternal outcomes show that there was a significant association found between type of delivery and family support received after delivery with maternal outcomes and total support during the third trimester (P < 0.05). It means that physical, emotional, and psychosocial support (total support) received by women would prevent complications during delivery, i.e., prevent Cesarean sections, results in the mother giving normal birth to baby. Hence, the mother needs total support during the third trimester.

Conclusion:
Total family support is needed by pregnant women during the third trimester to achieve maternal and fetal outcomes.
Outcome after Arthroscopic Meniscal Repair
Authors: Ashish Shukla , Ravindra Chauhan , Aditya Dwivedi , Ashish Pande 
Published: September 2024

Abstract

Objective:
The objective of this study was to evaluate the functional outcomes of all-inside meniscal repair using the Fast-Fix suturebased fixation device and its correlation with postoperative MRI findings in serving military personnel with symptomatic torn menisci.

Materials and Methods:
Thirty patients under 40 years of age with symptomatic meniscal tears were included in the study. Clinical evaluation, arthroscopic assessment, and meniscal repair using the Fast-Fix system were performed. Patients were followed up clinically and with postoperative MRI at one year. Functional outcomes were evaluated using the International Knee Documentation Committee (IKDC) form.

Results:
At one year postoperative follow-up, 10% of patients had excellent results, 66.6% had good results, 13.4% had fair results, and 10% had poor results according to the IKDC evaluation. MRI evaluation showed overall satisfactory results in 86.7% of patients. The Fast-Fix system demonstrated a success rate of 90% in this short-term follow-up study, with minimal complications.

Conclusion:
Arthroscopic all-inside meniscal repair using the Fast-Fix system showed promising clinical outcomes in serving military personnel with symptomatic torn menisci. The success rate was comparable to traditional suture techniques. Postoperative MRI provided valuable information for evaluating the physiological state of the repaired meniscus. Long-term followup studies are necessary to assess the structural and functional integrity of the repaired menisci over time.
Antimicrobial efficacy of clindamycin, linezolid, and calcium hydroxide as root canal medicaments on tubular infection against Enterococcus faecalis biofilm: An in vitro study
Authors: Bharathi Manisha Rani , Tilakchand Mahima , Horatti Priya , Chaliha Rideep 
Published: September 2024

ABSTRACT

Aim:
The aim of the study was to evaluate and compare the antimicrobial efficacy of linezolid, clindamycin, and calcium hydroxide (Ca(OH)2) as an intracanal medicament on Enterococcus faecalis biofilm.

Methods:
Fifty-six root blocks obtained from extracted single-rooted human teeth were decoronated, and the apical part of the root was removed to obtain a 6 mm cylinder of radicular dentin. The specimens were standardized for diameter, infected with microorganisms, and randomly divided into four groups. linezolid, clindamycin, Ca(OH)2, and methylcellulose (control) were placed in the root canal for 7 days. Dentin shavings were collected from 200 to 400 µm depth, and bacterial load was assessed by counting colony-forming units. Scores were statistically analyzed using the Kruskal–Wallis ANOVA and the Mann–Whitney test.

Results:
Linezolid and clindamycin had better antibacterial effects than control at both 200 µm and 400 µm depth after 7 days.

Conclusion:
Linezolid and clindamycin outperformed Ca(OH)2 in reducing bacteria and were equally efficient against E. faecalis but showed no significant differences in antimicrobial efficacy.
Phytochemical profiling of three Egyptian Phoenix dactylifera L. cultivars’ leaves with comparative positive impacts in controlling the streptozotocin diabetic rats
Authors: El Sawi Salma , El-Feky Amal M. , Elbatanony Marwa M. , El-khonezy Mohamed I. , Aly Hanan F. 
Published: September 2024

Background
Date palm, Phoenix dactylifera L., is a tropical plant of the Arecaceae family. No sufficient studies have been directed to evaluate leaves’ phytochemistry and bioactivity.

Objective
The major aim of this study is to assess the phytochemical configuration and antidiabetic effect of palm leaf extracts cultivars.

Materials and methods
It included total phenolic and flavonoid contents determination, ultra-performance liquid chromatography coupled with mass analysis, and isolation of the main compounds while, the biological investigation targeted in vitro bioactivities and detailed in vivo antidiabetic activity. Animals were inducted with streptozotocin dose (40 mg/kg b.wt) and treated with different extracts dose (200 mg/kg b.wt).

Results and conclusion
Phenolic and flavonoid contents in three cultivars of Egyptian date palm leaves, Samani, Hayani, and Zaghloul were 545.652, 90.609, and 2231.304 mg GAE/g for phenolics, and 535.63, 118.00, and 2185.00 mg CE/g for flavonoids, respectively. Additionally, UPLC-QTOF-MS/MS elicited the recognition of 28, 27, and 40 phytoconstituents in three extracts, respectively. However, Zaghloul extract exhibited higher in vitro antioxidant activity compared with vitamin C. In vivo treatment with the extracts in contrast to glibenclamide as a standard drug for 4 weeks caused a significant glucose level decrease by 64.81, 65.61, 69.61, and 66.87%, respectively. The tested extracts showed significant in-vitro and in-vivo anti-diabetic activity and ameliorated the other accompanying diabetes parameters e.g. liver and kidney. Histopathological investigation showed that treatment with Zaghloul leaf extract has better results than reference drug and nearly similar effects for other leaf extracts.
Breast Osteosarcoma with Chondroid Differentiation and Lung Metastasis
Authors: Samaila Modupeola O. , Ofunne Chioma N. , Kwapmi Nicholas , Dahir Huraira , Essien Otoobong , Chigozie Chikezie 
Published: September 2024

Abstract
Primary extra-skeletal osteosarcoma of the breast is uncommon, and less than 200 cases have been documented in literature since the first case reported in 1957. Breast osteosarcoma accounts for less than 1% and less than 5% of breast cancers and all sarcomas, respectively. We report a case of primary breast osteosarcoma with chondroid differentiation in a 45-year-old female with lung metastasis. The diagnosis of primary breast osteosarcoma requires extensive tissue sampling and comprehensive use of epithelial immunohistochemical antibodies to differentiate it from malignant phyllodes and metaplastic carcinoma with heterologous osseous or cartilaginous differentiation. The optimal treatment modality is wide excision with free margins and or mastectomy, even though the prognostic outcome is poor due to local recurrences and hematogenous spread to the lungs, liver, and bone. This report seeks to create heightened awareness among pathologists and clinicians.