bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of partially covered faces on trust attribution, sharing resources, and perceived fairness of one’s own choices in Ultimatum Game
Authors: Mastromatteo Libera Ylenia , Tedaldi Elisa , Scrimin Sara , Rubaltelli Enrico 
Published: September 2024

Covered faces have been linked with impaired emotion recognition; yet, it is entirely unexplored how an occlusion due to face masks may affect individuals’ behaviour in economic decisions. Across two studies, we explored whether partially covered faces (due to mask wearing or a horizontal black bar) and emotion displayed by the responder influence peoples’ sharing behaviour in the Ultimatum Game and the perceived fairness of one’s proposal. Study 1 showed participants were more willing to equally share their resources with a happy face (compared to a neutral one). In addition, they were more willing to make a fair proposal when the person displayed was not wearing a face mask. Our results also provide evidence that, when people had to judge how fair their proposal was, participants rated a fair proposal as fairer when responders showed happy faces without masks, while unfair proposals were rated as fairer with happy masked faces; similarly, angry faces led to fairer ratings for fair offers without masks and unfair offers with masks. Study 2 partially confirmed previous results, highlighting how a simple occlusion on the face does not have a direct effect on the proposal but moderates the effect of the displayed emotions. These findings indicate that social interactions might be affected by face occlusion, especially when it is represented by a face mask. Indeed, people might judge the same behaviour in different ways based on the fact that their counterpart has a partially covered face.
Comparison of risk of malignancy and predictive value of diagnostic categories defined by Papanicolaou Society of Cytopathology system and WHO reporting system for pancreaticobiliary cytopathology in solid pancreatic lesions
Authors: Vasas Béla , Fábián Anna , Bősze Zsófia , Hamar Sándor , Kaizer László , Tóth Tibor , Bacsur Péter , Resál Tamás , Bálint Anita , Farkas Klaudia , Molnár Tamás , Szepes Zoltán , Bor Renáta 
Published: September 2024

Background: The standardized diagnostic categories defined by the World Health Organization (WHO) reporting system support the interdisciplinary interpretation of cytological findings in the management of pancreatic cancer. Objective: To compare this classification to the Papanicolaou Society of Cytopathology (PSC) system in terms of predictive value and risk of malignancy (ROM) in solid pancreatic lesions. Design: Retrospective cohort study. Methods: All consecutive patients with solid pancreatic lesions who underwent endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) sampling at the University of Szeged from 2014 to 2021 were retrospectively enrolled. The predictive value and ROM of cytological findings were determined with comparison to histologic outcome and/or clinical follow-up. Results: A total of 521 EUS-FNAs were performed with a malignancy rate of 81.76%. In both classification systems, the absolute ROM of “non-diagnostic,” “negative for malignancy,” “atypical,” “suspicious for malignancy,” and “malignant” categories were 48.2%, 2.3%, 78.1%, 100.0%, and 99.4%, respectively. Despite the heterogeneous nature of the “neoplastic: other” category of the PSC system, the absolute ROM for solid lesions was 100%. Pancreatic neoplasm: high-risk/grade category including only two endosonographically solid cases of high-grade intraductal papillary mucinous neoplasms showed 100% ROM. There were no differences between PSC and WHO systems in sensitivity, specificity, and negative and positive predictive values: excluding the “atypical” category, these were 99.7%, 95.6%, 97.7%, and 99.5%, respectively. The “atypical” category considered benign resulted in a higher decrease in validity and negative predictive value, compared to “atypical” considered true malignant (93.6% vs 97.7% and 65.8% vs 97.7%). Conclusion: For solid pancreatic lesions, the WHO system was identical to the PSC system in terms of ROM and predictive values.
Prognostic impact of IL7R mutations on acute myeloid leukemia
Authors: Tao Qiqi , Wu Qiaoyuan , Xue Yutong , Chen Changkun , Zhou Ya , Shao Ruoyang , Zhang Haiyan , Liu Hui , Zeng Xiangzong , Zhou Lingling , Liu Qifa , Jin Hua 
Published: September 2024

Background: Interleukin-7 receptor ( IL7R) mutation has been demonstrated to be an adverse prognostic factor in acute lymphoblastic leukemia (ALL) patients. However, the effects of the IL7R mutation on acute myeloid leukemia (AML) have rarely been reported. Here, we investigated IL7R mutations and their effects on AML patients. Methods: A total of 346 newly diagnosed AML patients from January 2017 to July 2020 at Nanfang Hospital were analyzed in this study. A genomic panel of 167 gene targets was detected by next-generation sequencing. Results: Among 346 patients, 33 (9.5%) AML patients carried IL7R mutations. With a median follow-up of 50.7 months (95% confidence interval (CI) 17.3–62.2), the 5-year overall survival (OS) rates were 51.5% (95% CI 37.0%–71.0%) and 72.2% (95% CI 67.4%–77.3%; p = 0.008), the 5-year event-free survival (EFS) rates were 36.1% (95% CI 23.2%–57.1%) and 58.1% (95% CI 52.9%–63.8%; p = 0.005), the 5-year non-relapse mortality (NRM) were 21.4% (95% CI 8.5%–38.2%) and 6.2% (95% CI 3.7%–9.5%; p = 0.004) in the IL7R mutant ( IL7R MUT) group and non-IL7R mutant ( IL7R WT) group, respectively. There is no significant difference in the disease-free survival (75.1% vs 73.5%, p = 0.885) and cumulative incidence of relapse (25.7% vs 25.2%, p = 0.933) between IL7R MUT and IL7R WT group. Furthermore, patients who underwent hematopoietic stem cell transplantation (HSCT) still had more adverse outcomes in the IL7R MUT group than in the IL7R WT group (5-year OS: 61.9% vs 85.3%, p = 0.003). In the TET2 ( p = 0.013) and DNA methyltransferase 3A ( DNMT3A; p = 0.046) mutation subgroups, the presence of IL7R mutations was associated with worse OS than in AML patients without IL7R mutations. Conclusion: Our study demonstrated that the IL7R mutation is associated with an inferior prognosis for AML patients. Patients with IL7R mutations have higher NRM, shorter OS, and EFS than patients without IL7R mutations, even patients who have undergone HSCT. Future larger and multicentric prospective studies will be explored.
Differences in emotional reactions following ostracism: A comparison between youth with and without personality pathology
Authors: van den Hanenberg Danique A. M. , Schuiringa Hilde D. , Laceulle Odilia M. , Lucassen Inge G. M. , Scholte Ron H. J. , van der Heijden Paul T. 
Published: September 2024

Background: The sense of belonging is a fundamental human need and is important for establishing social relationships ( Baumeister & Leary, 1995 ). In certain social situations, the need to belong can be threatened by others, a phenomenon known as ostracism. Individuals react differently to these threatening situations. However, not much is known about the differences between youth with and without personality pathology in emotional reactions to ostracism. Therefore, the aim of this study was to investigate the differences in emotional reaction between these two groups. Method: Negative emotional reactions of youth (16–23 years old) diagnosed with personality pathology ( n = 34) were compared with youth from a community sample ( n = 44). The online game Cyberball was used as a measure for ostracism. A Repeated Measures Mixed-model ANOVA was performed to determine differences in negative affect (NA) between the groups at three measurement points. Results: Youth with personality pathology showed higher levels of NA at baseline than youth from the community sample. Although ostracism was conducted successfully, NA scores did not increase directly after playing Cyberball in both groups. Conclusions: Youth with personality pathology experience significantly more NA already at baseline, whereas they did not demonstrate stronger negative emotional reactions when confronted with ostracism than youth from a community sample.
Predictors of Empowerment Among Undergraduate Nursing Students: A Cross-Sectional Study
Authors: Al niarat Tahany 
Published: September 2024

ObjectiveTo predict the factors that influence undergraduate nursing students’ perception of empowerment.MethodsA cross-sectional design was used, and fourth-year nursing students ( n = 164) were selected using convenient sampling. The data collection methods included the Arabic version of self-reported questionnaires: The (LES), (LOGO-II), and (UNSASS).ResultsThe results showed a positive correlation between nursing students’ perception of empowerment and their attitudes toward learning. Also, the results showed a strong correlation between students’ perception of empowerment and their academic satisfaction. In addition, in-class teaching was found to be the strongest predictor of students’ perception of empowerment.ConclusionsVerified the factors that may contribute to promoting the teaching-learning process to focus and stress on them. Teachers and instructors should utilize the available resources in the teaching environment to maximize the learning outcomes. All these factors are not limited and will enhance the nursing students’ perception of empowerment.
Childhood Socioeconomic Status Affects Dental Pain in Later Life
Authors: Yamamoto T. , Cooray U. , Kusama T. , Kiuchi S. , Abbas H. , Osaka K. , Kondo K. , Aida J. 
Published: September 2024

Objectives: Lower socioeconomic status (SES) is associated with increased dental pain among children. Lower SES in childhood may also contribute to the experience of dental pain among older adults, regardless of the SES in later life. However, this association is still unclear. Methods: We used cross-sectional data from the 2019 Japan Gerontological Evaluation Study using self-administrated questionnaires to investigate the causal mediating pathways between childhood SES and dental pain in later life using several SES variables collected at older age as potential mediators. A total of 21,212 physically and cognitively independent participants aged 65 y or older were included in the analysis. The dependent variable was experiencing dental pain during the past 6 mo. The independent variable was the SES at the age of 15 y (low/middle/high). Ten covariates were selected covering demographics and other domains. Education, subjective current income, objective current income, objective current property ownership, and the number of remaining teeth were used as mediators. Prevalence ratios (PRs) and 95% confidence intervals (95% CIs) for dental pain by childhood SES were calculated using a modified Poisson regression model. Results: The mean age of the study participants was 74.5 ± 6.2 y, and 47.5% were men. Of these, 6,222 participants (29.3%) experienced dental pain during the past 6 mo, and 8,537 participants (40.2%) were of low childhood SES. Adjusted for covariates and mediators, the participants with middle and high childhood SES had a lower PR of dental pain (PR = 0.93 [95%, CI 0.89–0.98], PR = 0.79 [95% CI, 0.73–0.85], respectively). Almost 40% of the association between childhood SES and dental pain at older age was mediated via SES in later life and the number of teeth. Conclusions: This study reemphasizes the importance of support for early-life SES to maintain favorable oral health outcomes at an older age. Knowledge Transfer Statement: The results of this study can be used by policymakers to promote policies based on a life-course approach that supports children living in communities with low SES and helps them maintain favorable oral health outcomes into their older age.
COVID-19 vaccine coverage effectiveness among elderly with geographical information system mapping: what about Indonesia?
Authors: Wulan Widya Ratna , Widianawati Evina , wahyuni Anis Tri 
Published: September 2024

Background: The elderly are the next priority after health workers and public service workers get the COVID-19 vaccine to control morbidity and even mortality in the elderly who have a risk factor that is up to 60 times more severe than children. Objectives: This study aimed to spatially analyze the effectiveness of COVID-19 vaccine coverage among the elderly in Indonesia with geographic information system (GIS) mapping and to analyze the relationship between COVID-19 vaccine coverage in the elderly with the COVID-19 cure rate. Design: This quantitative study used secondary data on COVID-19 vaccination coverage in the elderly group of Central Java Province, Indonesia in 2021. Methods: Data were analyzed using a simple linear correlation test to test the relationship between variables with a 1,774,396 elderly sample size, then distributed using mapping of COVID-19 vaccination coverage using a GIS. Results: The relationship between COVID-19 vaccine dose-2 elderly coverage cure rate showed a strong relationship ( r = 0.677) and a positive pattern. The coefficient value with a determination of 0.459 means that the regression line equation obtained can explain 45.90% of the variation in the COVID-19 cure rate. There was a significant relationship between COVID-19 vaccine elderly coverage and the COVID-19 cure rate ( p-value = 0.005). Conclusion: Clinicians and public health workers should continue to encourage elderly vaccination at all recommended doses for eligible individuals.
From Freight to Future: Enhancing Philippines Logistics for Economic Competitiveness
Authors: Banomyong Ruth 
Published: September 2024

The purpose of this article is to evaluate the performance of logistics service providers (LSPs) in the Philippines, emphasising their impact on economic development and competitiveness. Utilising data collected from 126 respondents affiliated with the Philippines International Sea freight Forwarder Association and the Air cargo Forwarders of the Philippines Inc., the study identifies key performance indicators, including cost, time and reliability. The findings reveal that while LSPs in the Philippines maintain acceptable performance levels, significant challenges remain, particularly in domestic logistics. The study highlights that delays in customs processes and infrastructure inadequacies are major impediments to optimal logistics performance. Comparative analysis with other ASEAN countries shows that the Philippines lags in certain areas, particularly in delivery reliability and logistics infrastructure quality. The research also explores human resource issues, noting a high turnover rate and reliance on on-the-job training. Policy implications suggest the need for enhanced infrastructure, better regulatory frameworks and targeted human resource development to boost logistics performance. This study offers valuable insights for policy-makers and industry stakeholders aiming to improve the efficiency and competitiveness of the Philippines’ logistics services. JEL Codes: F0, F2
Insurance Development, Global Economic Policy Uncertainty and Geopolitical Risk: The Asymmetric Relationship Evidence from ASEAN-5
Authors: Lim Soyoung , Kyophilavong Phouphet , Soukchalern Phongsili 
Published: September 2024

Academia and governments have shown interest in studying the influence of the global economic policy uncertainty index (GEPU) and the geopolitical risk index (GPR) on insurance development. Several empirical studies have been conducted to examine the influence of GEPU and GPR on insurance development. Nevertheless, the empirical results failed to achieve consensus. This study aims to study the asymmetric impacts of the GEPU and the GPR on insurance sector development in ASEAN from 1990 to 2020. We used the linear panel autoregressive distributed lag (PARDL) approach and the asymmetric panel autoregressive distributed lag (PNARDL) approach. The results from the linear panel ARDL showed that GEPU and GPR had an impact on non-life insurance (NI), but both variables did not have an impact on life insurance (LI). Furthermore, the asymmetric panel ARDL showed no significant impact of positive shocks from GEPU had a positive impact on LI and NI, but the negative shocks from GEPU only had a positive impact on NI. Positive and negative shocks from GEPU lead to an increase in the NI. Interestingly, we found that the positive shocks of GPR led to an increase in NI, but positive or negative shocks of GPR did not have an impact on LI. Policymakers in ASEAN should closely look at the GEPU and the GPR for insurance policy development. JEL Codes: E6, G0
Calculating power for multilevel implementation trials in mental health: Meaningful effect sizes, intraclass correlation coefficients, and proportions of variance explained by covariates
Authors: Williams Nathaniel J. , Cardamone Nicholas C. , Beidas Rinad S. , Marcus Steven C. 
Published: September 2024

Background Despite the ubiquity of multilevel sampling, design, and analysis in mental health implementation trials, few resources are available that provide reference values of design parameters (e.g., effect size, intraclass correlation coefficient [ICC], and proportion of variance explained by covariates [covariate R2]) needed to accurately determine sample size. The aim of this study was to provide empirical reference values for these parameters by aggregating data on implementation and clinical outcomes from multilevel implementation trials, including cluster randomized trials and individually randomized repeated measures trials, in mental health. The compendium of design parameters presented here represents plausible values that implementation scientists can use to guide sample size calculations for future trials. Method We searched NIH RePORTER for all federally funded, multilevel implementation trials addressing mental health populations and settings from 2010 to 2020. For all continuous and binary implementation and clinical outcomes included in eligible trials, we generated values of effect size, ICC, and covariate R2 at each level via secondary analysis of trial data or via extraction of estimates from analyses in published research reports. Effect sizes were calculated as Cohen d; ICCs were generated via one-way random effects ANOVAs; covariate R2 estimates were calculated using the reduction in variance approach. Results Seventeen trials were eligible, reporting on 53 implementation and clinical outcomes and 81 contrasts between implementation conditions. Tables of effect size, ICC, and covariate R2 are provided to guide implementation researchers in power analyses for designing multilevel implementation trials in mental health settings, including two- and three-level cluster randomized designs and unit-randomized repeated-measures designs. Conclusions Researchers can use the empirical reference values reported in this study to develop meaningful sample size determinations for multilevel implementation trials in mental health. Discussion focuses on the application of the reference values reported in this study.
CD9 promotes TβR2–TβR1 association driving the transition of human dermal fibroblasts to myofibroblast under hypoxia
Authors: Huang Wanqi , Zhang Ze , Li Xin , Zheng Qingqing , Wu Chao , Liu Luojia , Chen Ying , Zhang Jiaping , Jiang Xupin 
Published: September 2024

Abstract
Background
During wound healing, fibroblast to myofibroblast transition is required for wound contraction and remodeling. While hypoxia is an important biophysical factor in wound microenvironment, the exact regulatory mechanism underlying hypoxia and fibroblast-to-myofibroblast transition remains unclear. We previously found that tetraspanin CD9 plays an important role in oxygen sensing and wound healing. Herein, we investigated the effects of physiological hypoxia on fibroblast-to-myofibroblast transition and the biological function and mechanism of CD9 in it.

Methods
Human skin fibroblasts (HSF) and mouse dermis wounds model were established under physiological hypoxia (2% O2). The cell viability and contractility of HSF under hypoxia were evaluated by CCK8 and collagen gel retraction, respectively. The expression and distribution of fibroblast-to-myofibroblast transition markers and CD9 in HSF were detected by Western blotting and immunofluorescence. CD9 slicing and overexpressing HSFs were constructed to determine the role of CD9 by small interfering RNA and recombinant adenovirus vector. The association of TβR2 and TβR1 was measured by immunoprecipitation to explore the regulatory mechanism. Additionally, further validation was conducted on mouse dermis wounds model through histological analysis.

Results
Enhanced fibroblast-to-myofibroblast transition and upregulated CD9 expression was observed under hypoxia in vitro and in vivo. Besides, reversal of fibroblast-to-myofibroblast transition under hypoxia was observed when silencing CD9, suggesting that CD9 played a key role in this hypoxia-induced transition. Moreover, hypoxia increased fibroblast-to-myofibroblast transition by activating TGF-β1/Smad2/3 signaling, especially increased interaction of TβR2 and TβR1. Ultimately, CD9 was determined to directly affect TβR1–TβR2 association in hypoxic fibroblast.

Conclusion
Collectively, these findings suggest that CD9 promotes TβR2–TβR1 association, thus driving the transition of human dermal fibroblasts to myofibroblast under hypoxia.
Epidemiological linkage between migraine and diabetes mellitus: a systematic review and meta-analysis
Authors: Ha Woo-Seok , Nguyen Vinh Khang , Chu Min Kyung 
Published: September 2024

Abstract
Background
This study aimed to elucidate the nature and extent of the associations between diabetes mellitus (DM) and migraine through a systematic review and meta-analysis.

Methods
We searched the PubMed, Web of Science, and Scopus databases without a specified start date until June 2, 2024. Cross-sectional and cohort studies analyzing the risk of migraine in individuals with DM and vice versa were included. Studies without at least age and sex adjustments were excluded. Data were extracted to calculate odds ratios (ORs) and hazard ratios (HRs). Risk of bias was assessed using the Newcastle–Ottawa Quality Assessment Scale.

Results
Eight cross-sectional studies (131,361 patients with DM and 1,005,604 patients with migraine) and four cohort studies (103,205 patients with DM patients and 32,197 patients with migraine) were included. Meta-analyses of the cross-sectional studies showed no significant overall association between DM and migraine. Subgroup analyses revealed that type 1 diabetes reduced the odds of having migraine (OR 0.48, 95% confidence interval [CI] 0.30–0.77), while migraine without aura (MO) increased the odds of having DM (OR 1.19, 95% CI 1.02–1.39). The cohort studies indicated that DM decreased the risk of developing migraine (HR 0.83, 95% CI 0.76–0.90), and a history of migraine increased the risk of developing DM (HR 1.09, 95% CI 1.01–1.17).

Conclusions
DM, particularly type 1 diabetes, is negatively associated with migraine occurrence, whereas migraine, especially MO, is positively associated with DM occurrence. However, most of the results remained at a low or very low level of evidence, indicating the need for further research.