bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trichotillomania, trichophagia, trichobezoar – summary of three cases. Endoscopic follow up scheme in trichotillomania
Authors: Wolski Marek , Gawłowska-Sawosz Marta , Gogolewski Michał , Wolańczyk Tomasz , Albrecht Piotr , Kamiński Andrzej 
Published: February 2016

CelTrichotillomania to brak kontroli nad przymusem wyrywania własnych włosów. Choroba ta dotyczy ok. 1% populacji. W 20% przypadków wyrywaniu włosów towarzyszy ich połykanie - trichofagia. U 30% pacjentów z trichofagią na skutek gromadzenia się włosów w przewodzie pokarmowym dochodzi do tworzenia trichobezoaru.MetodaW latach 2008-2014 operowano 3 pacjentki z powodu trichobezoaru. U jednej z operowanych pacjentek rozpoznano wcześniej trichotillomanię. U wszystkich pacjentek badanie USG i RTG jamy brzusznej wykazało obecność guza w żołądku. W TK jamy brzusznej wykonanym u dwóch pacjentek rozpoznano trichobezoar.WynikiBezoary były usunięte z żołądka podczas laparotomii z nacięciem żołądka a w jednym przypadku – zespół Roszpunki – również z jelita cienkiego. Po zakończeniu leczenia chirurgicznego przekazano pacjentki pod opiekę psychiatry.WnioskiProblemem pozostaje kontrola pooperacyjna pacjentów z trichobezoarem, a także pozostałych pacjentów z trichotillomanią pod kątem gromadzenia się włosów w przewodzie pokarmowym. Zaproponowano schemat kontroli endoskopowej pacjentów w 6, 12, i 24 miesiącu po operacji oraz u pacjentów z rozpoznaną trichotillomanią.
Demographic, clinical, and psychological factors influencing sexual activity cessation in patients with angiographically-confirmed ischaemic heart disease
Authors: Sobczak Maria , Qawoq Haval , Krawczyk Magdalena , Wierzbowska-Drabik Karina , Kasprzak Jarosław 
Published: February 2016

CelAktywność seksualna stanowi ważny aspekt zdrowia, rzutujący istotnie na samoocenę jakości życia. Celem pracy była analiza powrotu do aktywności seksualnej pacjentów z IHD po hospitalizacji związanej z diagnostyką inwazyjną naczyń wieńcowych oraz identyfikacja czynników predysponujących do zaprzestania aktywności seksualnej.MetodaRetrospektywnej analizie poddano 98 pacjentów z potwierdzoną angiograficznie chorobą wieńcową. Oceniano zarówno czynniki demograficzne, kliniczne jak i psychologiczne. Do oceny psychologicznej wykorzystano: Skalę Depresji Becka, Inwentarz Stanu i Cechy Lęku, Skalę Akceptacji Choroby oraz kwestionariusz do oceny jakości życia EuroQol-5D.WynikiZaprzestanie aktywności seksualnej po hospitalizacji w celu wykonania diagnostyki inwazyjnej naczyń wieńcowych dotyczyło blisko 1/3 pacjentów z IHD w obserwacji 6-miesięcznej. Nie stwierdzono istotnych statystycznie różnic w odsetkach pacjentów aktywnych seksualnie i z zaprzestaniem aktywności ze względu na płeć, natomiast młodsi pacjenci rzadziej zaprzestawali aktywności seksualnej (p=0,0056). Pacjenci dalej aktywni seksualnie odczuwali istotnie niższy poziom lęku jako cecha (p=0,0003) i jako stan (p=0,001). Pacjenci dalej aktywni seksualnie istotnie lepiej akceptowali chorobę (p=0,002) w chwili zakończenia hospitalizacji indeksowej, oraz odczuwali istotnie mniejsze natężenie depresji (p=0,02).WnioskiZaprzestanie aktywności seksualnej przez pacjentów z IHD po hospitalizacji związanej z koronarografią wiąże się z wiekiem, pozostawaniem poza związkiem, otyłością, niższą jakością życia, depresją, wyższym natężeniem lęku, niższą akceptacją choroby. Niedocenianie lub pomijanie przez lekarzy sfery zdrowia seksualnego pacjentów hospitalizowanych z powodu IHD, wpływa na powrót do aktywności seksualnej pacjentów. Pacjenci z IHD, którzy podczas hospitalizacji odbyli rozmowę z lekarzem na temat wpływu choroby kardiologicznej oraz przebytego inwazyjnego zabiegu na funkcjonowanie seksualne, częściej wracają do aktywności seksualnej w obserwacji 6-miesięcznej.
Prevalence of self-reported insomnia in general population of Poland
Authors: Nowicki Zbigniew , Grabowski Karol , Cubała Wiesław , Nowicka-Sauer Katarzyna , Zdrojewski Tomasz , Rutkowski Marcin , Bandosz Piotr 
Published: February 2016

CelCelem niniejszego doniesienia jest przedstawienie wyników badań dotyczących skarg związanych z zaburzeniami snu – subiektywnej bezsenności, przeprowadzonych w ramach programu oceny czynników ryzyka chorób układu sercowo-naczyniowego NATPOL.MetodaGrupa badana składała się z 2413 osób (w tym 1245 kobiet i 1168 mężczyzn) w wieku 18-79 lat i była reprezentatywna dla populacji Polski. W kwestionariuszu zaprojektowanym na potrzeby badania NATPOL uwzględniono pytania dotyczące przebiegu snu nocnego. Kwestionariusz był wypełniany przez przeszkolone pielęgniarki podczas osobistych wizyt w miejscu zamieszkania osób biorących udział w badaniu. W niniejszej pracy przedstawiono jedynie wyniki dotyczące skarg na problemy ze snem.WynikiRozpowszechnienie skarg dotyczących snu w grupie badanej wyniosło 50,5% (58,9% wśród kobiet i 41,4% wśród mężczyzn). Subiektywna bezsenność była najczęstsza wśród kobiet w wieku 60-79 lat. Deklarowało ją 74,8%. Trudności w zasypianiu deklarowało 60,2% badanych, 45,5% utrzymywanie ciągłości snu, 26,4% przedwczesne ranne budzenie.WnioskiWyniki badania sugerują, że subiektywna bezsenność jest w populacji Polski powszechnym problemem. Subiektywna bezsenność jest najczęstsza u kobiet i u osób w starszym wieku. Najczęściej skargi dotyczą trudności w zasypianiu.
Differential diagnosis of “Religious or Spiritual Problem” – possibilities and limitations implied by the V-code 62.89 in DSM-5
Authors: Prusak Jacek 
Published: February 2016

CelPrace nad przygotowaniem DSM-5 stały się pretekstem do badań i refleksji nad wpływem czynników religijnych i duchowych na fenomenologię, diagnozę różnicującą, przebieg, koniec i prognozę leczenia zaburzeń psychicznych. Celem artykułu jest przedstawienie podejścia klasyfikacji DSM do religii i duchowości w kontekście klinicznym. Chociaż ten system klasyfikacji nie obowiązuje w Polsce, w odróżnieniu od ICD, daje możliwość spojrzenia na doświadczenia religijne i duchowe w inny, niż jedynie, psychopatologiczny sposób.MetodaAnalizie zostanie poddany kod V 62.89 od strony historycznej, empirycznej oraz klinicznej.WynikiPojawienie się w DSM-IV nieredukcjonistycznego podejścia do religii i duchowości można uznać za przejaw rozwoju tej klasyfikacji psychiatrycznej w odniesieniu do kwestii diagnozy różnicującej religię i duchowość od psychopatologii. DSM-5 jeszcze wyraźniej umieścił religię i duchowość w kontekście kulturowym, i uwzględnił jej miejsce w diagnozie klinicznej. Pozostał jednak przy wcześniejszej postaci V 62.89, co stanowi przestrzeń do dalszej refleksji i badań nad zdefiniowaniem tego kodu biorąc pod uwagę możliwości i ograniczenia psychopatologii opisowej i struktury DSM.WnioskiRozwój DSM, od jego czwartej edycji, przyniósł ze sobą zmianę spojrzenia na religię i duchowość w kontekście diagnozy klinicznej. Wprowadzenie kodu V. 62.89 zwiększyło możliwości diagnozy różnicującej pomiędzy religią/duchowością a zdrowiem/psychopatologią. Położenie silniejszego akcentu na przejawy różnorodności kulturowej umożliwiło nieredukcjonistyczne i niepatologizujące spojrzenie na problemy religijne i duchowe. Z drugiej strony medykalizacja i psychiatryzacja różnych problemów egzystencjalnych jaka widoczna jest w kolejnych edycjach DSM zachęca do patologizującego spojrzenia na problemy religijne czy duchowe. Kliniczne spojrzenie na religię i duchowość powinno więc wyjść poza ograniczenia samego DSM.
Mental health nurses’ medicines management role: A qualitative content analysis
Authors: Hemingway Steve 
Published: February 2016

Aim This study explores the medicines management role undertaken by mental health nurses (MHNs) in a variety of clinical specialisms and contexts. Method Ten MHNs were interviewed and audiotaped. Qualitative content analysis of the transcribed interviews was undertaken. Results The findings evidence the wide-ranging skills and knowledge MHNS demonstrate when prescribing psychotropic medication, and how they engage with service users and other health professionals. Four themes emerged that illustrated how the participants undertook these interventions: medicines management in context; managing time; knowledge and skill used; and collaboration with other health professionals. Medicines management therefore needs a greater emphasis for service users to achieve optimum outcomes from the drugs they are prescribed.
Life-long learning and graphic design<p>Yaşam boyu öğrenme ve grafik tasarım
Authors: Çaydere Osman 
Published: February 2016

Design is an appearance of an entire product or part thereof composed of various elements and features, such as lines, forms, colors, shape, texture, material flexibility, or decorations, perceived by human senses. It is possible to say that designing process contains the steps of identification of issue or necessity, gathering information, creativity and discovery process, troubleshooting, and application. From this aspect, the basic goal of graphic design, a visual communication tool and art, is to convey a message or to introduce a product/service. Nowadays, computers and other relevant technological devices have come to the area of usage of graphic design. In this study, it is aimed to find out where education of graphic design having importance for life-long learning is provided by which institutions in our country, and the present status of municipalities and Public Training Centers, among mass education institutions, in central districts of Ankara Province with respect to graphic design education. ÖzetTasarım, bir ürünün tamamının veya bir parçasının çizgi, şekil, renk, biçim, doku, malzemenin esnekliği veya süslemesi gibi insan duyuları ile algılanabilen çeşitli unsur ve özelliklerin oluşturduğu görünümdür. Tasarım sürecinin; problemin ya da ihtiyacın tanımı, bilgi toplama, yaratıcılık ve buluş süreci, çözüm bulma, uygulama evrelerini içerdiği söylenebilir. Bu yönüyle, görsel bir iletişim aracı ve sanatı olan grafik tasarımın temel amacı bir mesaj iletmek veya bir ürünü- hizmeti tanıtmaktır. Günümüzde bilgisayar ve ilgili diğer teknolojik aletler grafik tasarımın kullanım alanına girmiştir. Bu araştırmada, yaşam boyu öğrenme açısından önemli bir yere sahip olan grafik tasarım eğitiminin ülkemizde hangi kurumlarda verildiği ve Ankara ili merkez ilçelerinde yaygın eğitim kurumlarından belediyelerin ve halk eğitim merkezlerinin grafik tasarım eğitimi açısından mevcut durumunun ortaya konulması amaçlanmıştır.
Relation of life-long learning and social media in music education<p>Müzik eğitiminde hayat boyu öğrenme ve sosyal medya ilişkisi
Authors: Öztosun Çaydere Öznur 
Published: February 2016

In the study, an answer is looked for to the question of how youngsters utilize Facebook in acquisition of knowledge of music. By determining the process of acquisition of knowledge of music, communication and access to knowledge by those students attending to music departments of universities via Facebook, a social media environment, it is aimed to set forth its relation to life-long learning. The study will be performed in a format of case study as a qualitative research in this context by means of interview with students of music department, who are Facebook users. In line with study results, suggestions shall be put forward. ÖzetYaşam boyu öğrenme, bireysel veya toplumsal gerçekleşen öğrenmeler olarak tanımlanabilir. Yaşam boyu öğrenme planlı veya plansız öğrenmeleri kapsayabilir. Plansız öğrenmeler kapsamında sosyal medyanın bilgiye ulaşma ve bilgiyi kullanma yönünde yaşam boyu öğrenmeye katkı sağladığı düşünülebilir. Bu bağlamda araştırmada, müzik bölümü öğrencilerinin müzik konusunda Facebook’ tan nasıl yararlandıkları sorusuna cevap aramaktadır. Üniversitelerin müzik bölümlerinde okuyan öğrencilerin sosyal medya ortamı olan Facebook tan müzik konusunda bilgi edinme, iletişim ve bilgiye ulaşma süreçlerinin tespit edilerek, hayat boyu öğrenmeyle olan ilişkisinin ortaya konulması amaçlanmıştır. Araştırma, bu kapsamda nitel araştırma türünde, durum çalışması deseninde, Facebook kullanıcısı olan müzik bölümü öğrencileri ile görüşme tekniği kullanılarak gerçekleştirilecektir. Araştırma sonuçları paralelinde öneriler sunulacaktır.
Post-Abortion Syndrome and nursing approaches<p>Post-Abortus Sendromu ve hemşirelik yaklaşımları
Authors: Aba Yılda Arzu , Ergün Gül 
Published: February 2016

The relation between the life outputs, are associated especially with the mental health outputs at Abortus and the period that follows it. Post-Abortus Syndrome (PAS) is the concept of abortus trauma management that show up with the chronic or delayed symptoms as a result of the hidden emotional reactions that are experienced because of the post-abortus physical and psychological trauma. The individual, the systemic and the social factors that are existing at post-Abortus women affect PAS development. The interventions, in general, that are oriented towards mental problems of the individual at the PAS period, focused on the individual’s sufficiency and efficiency for coping with all the problems that are faced in her life. There is no any program that is developed for post-Abortus women or their family in our country. It is important for the individual who is diagnosed with PAS to receive consultancy from a health professional for her recovery from the period. ÖzetAbortus ve bunu izleyen süreçte yaşam sonuçları arasındaki ilişki özellikle mental sağlık sonuçlarıyla ilişkilendirilmektedir. Post-Abortus Sendromu (PAS), abortus sonrası fiziksel ve psikolojik travma nedeniyle deneyimlenen gizlenmiş duygusal tepkiler sonucu, kronik ya da gecikmiş belirtilerle ortaya çıkan abortus travmasını yönetebilme kavramıdır. Abortus sonrası kadınlarda var olan bireysel, sistemik ve sosyal faktörler PAS gelişimini etkilemektedir. PAS dönemindeki bireyin ruhsal sorunlarına yönelik yapılan müdahaleler genel olarak, bireyin yaşamında karşılaştığı tüm sorunlarla başetmesinde yeterli ve etkili hale gelmesine odaklanır. Ülkemizde abortus sonrası kadınlara ya da ailelerine yönelik geliştirilen herhangi bir program bulunmamaktadır. PAS tanısı alan bireyin süreci atlatabilmesi için sağlık profesyoneli tarafından danışmanlık alması önemlidir.
Age-Related Changes in Postural Sway Are Not Consistent Between Land and Aquatic Environments
Authors: Bressel Eadric , Louder Talin J. , Dolny Dennis G. 
Published: February 2016

Background and Purpose:
Quantifying how the environment (land vs water) influences age-related changes in postural sway is important for the development of new therapies that improve balance. The authors are not aware of any previous studies that have compared postural sway in an aquatic environment between age groups or when water depth and/or perturbations are incorporated into the comparison. The purpose of this study was to compare the effect of water depth and jet intensity on postural sway in older and younger adults.

Methods:
Sixteen older (age = 62.8 ± 9.56 years) and 15 younger (age = 22.5 ± 1.85 years) adults participated. Participants stood quietly for 90 seconds on land and at various water depths and jet intensities while center of pressure (CoP) sway was recorded using a force platform.

Results:
Statistical comparisons revealed that CoP range and area measurements were different between land and aquatic conditions (P = .04 − .001). For example, CoP sway area in chest deep water (8.51 ± 2.97 cm2) was greater than on land (2.41 ± 1.37 cm2; effect size = 2.05). Furthermore, CoP sway area at the 60% jet intensity (71.4 ± 31.2 cm2) was substantially greater than at the 20% jet intensity (12.4 ± 6.23 cm2; effect size = 1.89). Surprisingly, the proportion of change across water depths and jet intensities was not consistent between older and younger groups as indicated by significant age by environment interactions (P = .03 − .001). Follow-up tests indicated that older adults swayed less than younger adults in water at the level of the hip (effect sizes = 0.42-0.94) and when water jets were applied at a 60% jet intensity (effect sizes = 0.63-1.97).

Conclusions:
Water immersion to the chest with high jet intensities produces the greatest CoP sway in both groups. This is likely a result of buoyancy and perturbation intensity. Less sway in the older group may reflect a strategy that reduces degrees of freedom for this group when faced with these stability challenges.
AG and UAG induce β-casein expression via activation of ERK1/2 and AKT pathways
Authors: Li Sunan , Liu Juxiong , Lv Qingkang , Zhang Chuan , Xu Shiyao , Yang Dongxue , Huang Bingxu , Zeng Yalong , Gao Yingjie , Wang Wei 
Published: February 2016

Abstract
The ghrelin peptides were found to circulate in two major forms: acylated ghrelin (AG) and unacylated ghrelin (UAG). Previous studies showed that AG regulates β-casein (CSN2) expression in mammary epithelial cells. However, little is known about the mechanisms by which AG regulates CSN2 gene and protein expression. Evidence suggests that UAG has biological activity through GHSR1a-independent mechanisms. Here, we investigated the possible GHSR1a-mediated effect of UAG on the expression of CSN2 in primary bovine mammary epithelial cells (pbMECs) isolated from lactating cow. We found that both AG and UAG increase the expression of CSN2 in a dose-dependent manner in pbMECs in comparison with the control group. Increased expression of CSN2 was blocked by [D-Lys3]-GHRP-6 (an antagonist of the GHSR1a) and NF449 (a Gs-α subunit inhibitor) in pbMECs. In addition, both AG and UAG activated AKT/protein kinase B (AKT) and extracellular signal-regulated kinase 1/2 (ERK1/2) pathways, whereas [D-Lys3]-GHRP-6 and NF449 inhibited the phosphorylation of AKT and ERK1/2 in pbMECs respectively. Blockade of ERK1/2 and AKT signaling pathways prevented the expression of CSN2 induced by AG or UAG. Finally, we found that both AG and UAG cause cell proliferation through identical signaling pathways. Taken together, these results demonstrate that both AG and UAG act on ERK1/2 and AKT signaling pathways to facilitate the expression of CSN2 in a GHSR1a-dependent manner.
A Twin Study of Perthes Disease
Authors: Metcalfe David , Van Dijck Stephanie , Parsons Nicolas , Christensen Kaare , Perry Daniel C. 
Published: February 2016

BACKGROUND:
Legg-Calvé-Perthes disease (LCPD) is an idiopathic avascular necrosis of the femoral head. Its etiology is poorly understood, although previous studies have implicated low birth weight and possible genetic determinants. The aim of this study was to identify potential birth weight and genetic associations with LCPD.

METHODS:
We extracted all twin pairs from the Danish Twin Registry (DTR) in which at least 1 individual had LCPD. The DTR captures every twin pair born alive in Denmark, and those with LCPD were identified by using health record linkage. Probanwise concordance was calculated to describe the likelihood that any given individual had LCPD if their co-twin was also diagnosed.

RESULTS:
There were 81 twin pairs: 10 monozygotic, 51 dizygotic, and 20 unclassified (unknown zygosity [UZ]). There was no association between birth weight and being the affected co-twin. Four pairs (2 dizygotic and 2 UZ) were concordant for LCPD, which is greater than would be expected assuming no familial aggregation. There were no concordant monozygotic twin pairs. The overall probandwise concordance was 0.09 (95% confidence interval [CI]: 0.01–0.18): 0.00 for the monozygotic, 0.08 (95% CI: 0.00–0.18) for the dizygotic, and 0.18 (95% CI: 0.00–0.40) for the UZ twin pairs.

CONCLUSIONS:
This study found evidence of familial clustering in LCPD but did not show a genetic component. The absolute risk that a co-twin of an affected individual will develop LCPD is low, even in the case of monozygotic twin pairs.
Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho–Deficient Model
Authors: Kawai Masanobu , Kinoshita Saori , Ozono Keiichi , Michigami Toshimi 
Published: February 2016

Inorganic phosphate (Pi) has been implicated in the pathogenesis of accelerated aging; however, the underlying mechanisms remain elusive. Herein, we demonstrated in cultured cells and in vivo that increased levels of extracellular Pi activated the AKT/mammalian target of rapamycin complex 1 (mTORC1) pathway by suppressing membrane-bound phosphatase and tensin homolog (PTEN) levels in a manner requiring the sodium-dependent Pi transporter PiT‑1. High levels of extracellular Pi also led to phosphorylation of Ser/Thr clusters in the C‑terminal tail of PTEN, which has been shown to dissociate PTEN from the membrane. Notably, blockade of mTORC1 activity by rapamycin treatment prolonged the life span of hyperphosphatemic α‑Klotho–deficient (Kl
−/−) mice. Dietary correction of hyperphosphatemia or treatment with rapamycin also rescued the brown adipose tissue dysfunction and oxidative damage observed in Kl
−/− mice. Furthermore, rapamycin treatment partially rescued these effects and extended the life span when Kl
−/− mice were maintained on a high-phosphate diet. Finally, rapamycin reduced circulating Pi levels in Kl
−/− mice, apparently by decreasing the localization of sodium-dependent Pi transport protein 2a at the renal brush border membrane. Therefore, the activation of mTORC1 may create a vicious loop that exacerbates the retention of Pi, which in turn may enhance oxidative damage and ultimately shorten the life span of Kl
−/− mice. These results demonstrate that Pi has important roles in the aging process, and the blockade of mTORC1 may have therapeutic potential for premature aging-like symptoms associated with hyperphosphatemia.
Thunderstorm Electrification
Authors: Bradshaw Stephanie Marie 
Published: February 2016

Understanding how thunderstorms work is important as it can help assess risks associated with electrical activity in thunderstorms and electrical activity in other areas such as volcanic eruptions, heavy snowstorms, and large hurricanes.Â We studied the electrification processes in thunderstorms by investigating literature resources to understand what was known about the electrification processes in thunderstorms.Â The electrification processes were then studied by investigating what observations could be made using CAERENet (Carthage Atmospheric Electricity Research and Education Network) electric field mills to better understand how thunderstorms electrify.Â In order to understand what could be observed about thunderstorm electrification with an electric field mill, we built mathematical models of electric charge, current, and electric field using Python.Â A comparison between model data and electric field mill data will be used to better understand electrification processes in a naturally occurring thunderstorm.
Can Dark Matter Halos Change Shape? Examining the Adams Instability in Triaxial Systems
Authors: Dowling Evan 
Published: February 2016

A recently discovered instability causes non-spherical orbits within dark matter halos to exponentially diverge into more spherical orbits.Â The instability was studied in limited rÃ©gimes within the Adams et al. (2007) work.Â This project has replicated and extend the ideas to a static potential system that is accurate to all distances away from the potentialâ€™s center as well as found an easy visualization for the arising instability.Â A better understanding of dark mattersâ€™ behavior will help explain dark mattersâ€™ halo structure and mass distribution that surround galaxies.
Star Forming Rates and HI Gas Content in Galaxy Groups
Authors: Martens Sarah Katherine 
Published: February 2016

We compare the star formation rates with the respective HI properties of 4854 galaxies in 743 different groups. Using data from the SDSS and the GALEX all sky survey (AIS) we measure the star formation rates and NUV-r colors as a function of the total group mass, position within the group, and HI content as derived from the Arecibo Legacy Fast ALFA (ALFALFA) survey. The NUV-r colors are consistent with star forming field galaxies. We show how the quenching of the star formation is correlated with galaxy HI content and how both are affected by a group environment.Â Â