bluuebunny/crossref_metadata_2025_split huggingface dataset:
No apparent superluminal motion in the first-known jetted tidal disruption event Swift J1644+5734
Authors: Yang J. , Paragi Z. , van der Horst A. J. , Gurvits L. I. , Campbell R. M. , Giannios D. , An T. , Komossa S. 
Published: May 2016

Abstract
The first-known tidal disruption event (TDE) with strong evidence for a relativistic jet – based on extensive multiwavelength campaigns – is Swift J1644+5734. In order to directly measure the apparent speed of the radio jet, we performed very long baseline interferometry (VLBI) observations with the European VLBI network (EVN) at 5 GHz. Our observing strategy was to identify a very nearby and compact radio source with the real-time e-EVN, and then utilize this source as a stationary astrometry reference point in the later five deep EVN observations. With respect to the in-beam source FIRST J1644+5736, we have achieved a statistical astrometric precision about 12 μas (68 per cent confidence level) per epoch. This is one of the best phase-referencing measurements available to date. No proper motion has been detected in the Swift J1644+5734 radio ejecta. We conclude that the apparent average ejection speed between 2012.2 and 2015.2 was less than 0.3c with a confidence level of 99 per cent. This tight limit is direct observational evidence for either a very small viewing angle or a strong jet deceleration due to interactions with a dense circum-nuclear medium, in agreement with some recent theoretical studies.
AKARI far-infrared maps of the zodiacal dust bands
Authors: Ootsubo Takafumi , Doi Yasuo , Takita Satoshi , Nakagawa Takao , Kawada Mitsunobu , Kitamura Yoshimi , Matsuura Shuji , Usui Fumihiko , Arimatsu Ko 
Published: May 2016

Abstract
Zodiacal emission is thermal emission from interplanetary dust. Its contribution to the sky brightness is non-negligible in the region near the ecliptic plane, even in the far-infrared (far-IR) wavelength regime. We analyze zodiacal emission observed by the AKARI far-IR all-sky survey, which covers 97% of the entire sky at arcminute-scale resolution in four photometric bands, with central wavelengths of 65, 90, 140, and 160 μm. AKARI detected small-scale structures in the zodiacal dust cloud, including the asteroidal dust bands and the circumsolar ring, at far-IR wavelengths. Although the smooth component of the zodiacal emission structure in the far-IR sky can be reproduced well by models based on existing far-IR observations, previous zodiacal emission models have discrepancies in the small-scale structures compared with observations. We investigate the geometry of the small-scale dust-band structures in the AKARI far-IR all-sky maps and construct template maps of the asteroidal dust bands and the circumsolar ring components based on the AKARI far-IR maps. In the maps, ± 1$_{.}^{\circ}$4, ± 2$_{.}^{\circ}$1, and ± 10° asteroidal dust-band structures are detected in the 65 μm and 90 μm bands. A possible ± 17° band may also have been detected. No evident dust-band structures are identified in either the 140 μm or the 160 μm bands. By subtracting the dust-band templates constructed in this paper, we can achieve a similar level of flux calibration of the AKARI far-IR all-sky maps in the |β| &lt; 40° region to that in the region for |β| &gt; 40°.
Ultramicronized palmitoylethanolamide in spinal cord injury neuropathic pain: a randomized, double-blind, placebo-controlled trial
Authors: Andresen Sven R. , Bing Jette , Hansen Rikke M. , Biering-Sørensen Fin , Johannesen Inger L. , Hagen Ellen Merete , Rice Andrew S. C. , Nielsen Jørgen F. , Bach Flemming W. , Finnerup Nanna B. 
Published: May 2016

Abstract
Neuropathic pain and spasticity after spinal cord injury (SCI) represent significant problems. Palmitoylethanolamide (PEA), a fatty acid amide that is produced in many cells in the body, is thought to potentiate the action of endocannabinoids and to reduce pain and inflammation. This randomized, double-blind, placebo-controlled, parallel multicenter study was performed to investigate the effect of ultramicronized PEA (PEA-um) as add-on therapy on neuropathic pain in individuals with SCI. A pain diary was completed and questionnaires were completed before and after the 12-week treatment with either placebo or PEA-um. The primary outcome measure was the change in mean neuropathic pain intensity from the 1-week baseline period to the last week of treatment measured on a numeric rating scale ranging from 0 to 10. The primary efficacy analysis was the intention to treat (baseline observation carried forward). Secondary outcomes included a per protocol analysis and effects on spasticity, evoked pain, sleep problems, anxiety, depression, and global impression of change. We randomized 73 individuals with neuropathic pain due to SCI, of which 5 had a major protocol violation, and thus 68 were included in the primary analysis. There was no difference in mean pain intensity between PEA-um and placebo treatment (P = 0.46, mean reductions in pain scores 0.4 (−0.1 to 0.9) vs 0.7 (0.2-1.2); difference of means 0.3 (−0.4 to 0.9)). There was also no effect of PEA-um as add-on therapy on spasticity, insomnia, or psychological functioning. PEA was not associated with more adverse effects than placebo.
The landscape of gene fusions in hepatocellular carcinoma
Authors: Zhu Chengpei , Lv Yanling , Wu Liangcai , Guan Jinxia , Bai Xue , Lin Jianzhen , Liu Tingting , Haohai Zhang , Anqiang Wang , Yuan Xie , Xueshuai Wan , Yongchang Zheng , Xiaobo Yang , Ruoyu Miao , Simon C. Robson , Xinting Sang , Xue Chenghai , Zhao Haitao 
Published: May 2016

AbstractMost hepatocellular carcinoma (HCC) patients are diagnosed at advanced stages and suffer limited treatment options. Challenges in early stage diagnosis may be due to the genetic complexity of HCC. Gene fusion plays a critical function in tumorigenesis and cancer progression in multiple cancers, yet the identities of fusion genes as potential diagnostic markers in HCC have not been investigated.Paired-end RNA sequencing was performed on noncancerous and cancerous lesions in two representative HBV-HCC patients. Potential fusion genes were identified by STAR-Fusion in STAR software and validated by four publicly available RNA-seq datasets. Fourteen pairs of frozen HBV-related HCC samples and adjacent non-tumor liver tissues were examined by RT-PCR analysis for gene fusion expression.We identified 2,354 different gene fusions in the two HBV-HCC patients. Validation analysis against the four RNA-seq datasets revealed only 1.8% (43/2,354) as recurrent fusions that were supported by public datasets. Comparison with four fusion databases demonstrated that three (HLA-DPB2-HLA-DRB1, CDH23-HLA-DPB1, and C15orf57-CBX3) out of 43 recurrent gene fusions were annotated as disease-related fusion events. Nineteen were novel recurrent fusions not previously annotated to diseases, including DCUN1D3-GSG1L and SERPINA5-SERPINA9. RT-PCR and Sanger sequencing of 14 pairs of HBV-related HCC samples confirmed expression of six of the new fusions, including RP11-476K15.1-CTD-2015H3.2.Our study provides new insights into gene fusions in HCC and could contribute to the development of anti-HCC therapy. RP11–476K15.1-CTD–2015H3.2 may serve as a new therapeutic biomarker in HCC.
Small retailer’s new product acceptance in emerging market: a grounded theory approach
Authors: Shaikh Ateeque , Gandhi Aradhana 
Published: May 2016

Purpose
– The purpose of this paper is to propose a model of small retailers’ new product acceptance criteria using a grounded theory approach in an emerging market, India.

Design/methodology/approach
– Empirical research on retailers’ new product acceptance either takes survey design or modeling approach. This study uses grounded theory approach to systematically collect and analyze data to generate a model for the small retailers’ new product acceptance in an emerging market, India. In depth interviews with ten small retailers, five situated in small market town and five in a metro were conducted.

Findings
– Retail margin on offer is the first and foremost criteria considered while accepting a new product along with product and market-related factors. The small retailers spelt out the tradeoff decision on retail margins while accepting a new product. The tradeoff criteria that emerged during the analysis are trade and promotional support, sales potential of the product, salesperson relationship with the retailer, aspects of fairness in the relationship, corporate reputation, relevant product information, and availability of the product with other retail competitors.

Practical implications
– The study suggests that marketers have to maintain healthy relationship with the channel partners especially the retailers who are in direct contact with the final consumer. The findings of the study suggest that marketers specifically need to take into consideration aspects of fairness and encourage salespersons to build and foster relationships with small retailers.

Originality/value
– This study is one of the few study which uses grounded theory approach to propose a retailer’s new product acceptance model.
A lean thinking and simulation-based approach for the improvement of routing operations
Authors: Villarreal Bernardo , Garza-Reyes Jose Arturo , Kumar Vikas 
Published: May 2016

Purpose– The improvement of routing operations performance has been of great concern for organisations. This has led to the development of alternative lean-based methods, however the literature research on the applications of lean thinking in the transportation sector is still considered rather limited. The purpose of this paper is to present a lean thinking and simulation-based approach to improve the efficiency of warehousing and routing operations.Design/methodology/approach– The paper reviews the existing literature in the area of lean transportation and then presents and applies a novel approach to improve the vehicle routing operations of a Mexican firm. The proposed approach suggests the classification of wastes into those relevant to transport operations, their identification through a transportation value stream mapping study, and the use of the transportation overall vehicle effectiveness (TOVE) index for the measure of the overall performance of the transport operations.Findings– The results obtained from the case study indicate that the proposed approach is an effective alternative for the improvement of vehicle routing operations as the number of routes decreased from 30 to 22 and the distance travelled by 32 per cent. Similarly, the average number of clients served by each route increased by 23 per cent as well as the TOVE index increased from 6.9 to 19.3 per cent. The TOVE component measures of vehicle performance and operating availability efficiencies also increased significantly while quality issues, in the form of number of customers not served per route, were reduced from six to zero.Originality/value– The improvement of routing operations performance has been traditionally addressed through operations research and mathematical modelling approaches. This paper presents an alternative and novel lean thinking and simulation-based approach to improve the efficiency of routing operations.
The impact of telephone crisis services on suicidal users: a systematic review of the past 45 years
Authors: Assing Hvidt Elisabeth , Ploug Thomas , Holm Søren 
Published: May 2016

Purpose– Telephone crisis services are increasingly subject to a requirement to “prove their worth” as a suicide prevention strategy. The purpose of this paper is to: first, provide a detailed overview of the evidence on the impact of telephone crisis services on suicidal users; second, determine the limitations of the outcome measures used in this evidence; and third, suggest directions for future research.Design/methodology/approach– MEDLINE via Pubmed (from 1966), PsycINFO APA (from 1967) and ProQuest Dissertation and Theses (all to 4 June 2015) were searched. Papers were systematically extracted by title then abstract according to predefined inclusion and exclusion criteria.Findings– In total, 18 articles met inclusion criteria representing a range of outcome measures: changes during calls, reutilization of service, compliance with advice, caller satisfaction and counsellor satisfaction. The majority of studies showed beneficial impact on an immediate and intermediate degree of suicidal urgency, depressive mental states as well as positive feedback from users and counsellors.Research limitations/implications– A major limitation pertains to differences in the use of the term “suicidal”. Other limitations include the lack of long-term follow-up and of controlled research designs. Future research should include a focus on long-term follow-up designs, involving strict data protection. Furthermore, more qualitative research is needed in order to capture the essential nature of the intervention.Originality/value– This paper attempts to broaden the study and the concept of “effectiveness” as hitherto used in the literature about telephone crisis services and offers suggestions for future research.
Figshare: a universal repository for academic resource sharing?
Authors: Thelwall Mike , Kousha Kayvan 
Published: May 2016

Purpose
– A number of subject-orientated and general websites have emerged to host academic resources. The purpose of this paper is to evaluate the uptake of such services in order to decide which depositing strategies are effective and should be encouraged.

Design/methodology/approach
– This paper evaluates the views and shares of resources in the generic repository Figshare by subject category and resource type.

Findings
– Figshare use and common resource types vary substantially by subject category but resources can be highly viewed even in subjects with few members. More active subject areas do not tend to have more viewed or shared resources.

Research limitations/implications
– The view counts and share counts analysed may reflect author accesses or may be spammed.

Practical implications
– Limited uptake of Figshare within a subject area should not be a barrier to its use. Several highly successful innovative uses for Figshare show that it can reach beyond a purely academic audience.

Originality/value
– This is the first analysis of the uptake and use of a generic academic resource sharing repository.
Utilizing overtly political texts for fully automatic evaluation of political leaning of online news websites
Authors: Zhitomirsky-Geffet Maayan , David Esther , Koppel Moshe , Uzan Hodaya 
Published: May 2016

Purpose– Reliability and political bias of mass media has been a controversial topic in the literature. The purpose of this paper is to propose and implement a methodology for fully automatic evaluation of the political tendency of the written media on the web, which does not rely on subjective human judgments.Design/methodology/approach– The underlying idea is to base the evaluation on fully automatic comparison of the texts of articles on different news websites to the overtly political texts with known political orientation. The authors also apply an alternative approach for evaluation of political tendency based on wisdom of the crowds.Findings– The authors found that the learnt classifier can accurately distinguish between self-declared left and right news sites. Furthermore, news sites’ political tendencies can be identified by automatic classifier learnt from manifestly political texts without recourse to any manually tagged data. The authors also show a high correlation between readers’ perception (as a “wisdom of crowds” evaluation) of the bias and the classifier results for different news sites.Social implications– The results are quite promising and can put an end to the never ending dispute on the reliability and bias of the press.Originality/value– This paper proposes and implements a new approach for fully automatic (independent of human opinion/assessment) identification of political bias of news sites by their texts.
Countries of the world: free and subscription information sources
Authors: Shores Mark 
Published: May 2016

Purpose
This paper aims to summarize the quality and usefulness of several online resources, both subscription and free, for finding information on countries of the world.

Design/methodology/approach
The paper describes several free and commercial sources that can be used for conducting research on countries of the world, evaluates them and makes recommendations regarding their use and appropriateness for specific clientele.

Findings
There are many free resources that can be used for locating information on countries of the world, but researchers needing current and in-depth economic and demographic information may need to consult subscription databases.

Research limitations/implications
This paper intentionally limits its analysis to resources that provide basic statistical and narrative information, along with descriptions of culture; online tools for gathering comprehensive data on country economics and demographics have been excluded for purposes of brevity.

Originality/value
This paper offers a comparative overview, survey and analysis of multiple references sources that can be utilized to locate country information, which will be of value to information professionals, as well as information seekers.
A Question of Culture or Economics? Public Attitudes to the European Union in Britain
Authors: Curtice John 
Published: May 2016

AbstractPrevious research has suggested that attitudes towards the European Union (EU) are shaped by two sets of considerations—economic and cultural. Using data from the 2015 British Social Attitudes survey, this article assesses which matters more in shaping attitudes in Britain towards the EU as the country prepares to vote in a referendum on whether it should remain in or leave the European Union. It shows that while concern about the cultural consequences of EU membership is widespread, voters are inclined to think that membership is economically beneficial. This cultural concern underpins a widespread scepticism about Europe, but voters are only likely to want to leave the EU if they are also convinced of the economic case for doing so.
Shear stress regulates endothelial cell function through SRB1‐eNOS signaling pathway
Authors: Zhang Ying , Liao Bin , Li Miaoling , Cheng Min , Fu Yong , Liu Qing , Chen Qi , Liu Hongduan , Fang Yibing , Zhang Gen , Yu Fengxu 
Published: May 2016

SummaryAimThe aim of this study was to explore whether transmembrane flow shear stress could regulate eNOS expression and mediate endothelial cell function via SR‐B1 signaling transduction.MethodsParallel‐plate flow chamber was used to impose laminar shear stress and evaluate the effect of shear stress upon human umbilical vein endothelial cells (HUVECs). The expression of SR‐B1 and eNOS at both RNA and protein levels was detected under different dynamic conditions. RNA interference and gene transfection were performed to overexpress and knock down the SRB1 to confirm the role of SR‐B1‐eNOS signaling pathway.ResultsThe expression levels of SR‐B1 and eNOS were downregulated when HUVECs were treated with 4.2 dyne/cm2 shear stress compared with those of the control group. However, the expression of SR‐B1 and eNOS was upregulated as HUVECs exposed to 8.4 and 15 dyne/cm2 shear stress. When exposed to 8.4 dyne/cm2, SR‐B1 and eNOS expression was significantly higher compared with those of the other groups. When SR‐B1 was knocked down through RNAi technique, the expression of eNOS was significantly downregulated than those of the other groups. While overexpression of SR‐B1 could upregulate eNOS significantly.ConclusionShear stress regulates endothelial cell function through SR‐B1‐eNOS signaling pathway. SR‐B1 may play a pivotal role in the process of anti‐atherosclerosis.
Self‐tonometry as a complement in the investigation of glaucoma patients
Authors: Chen Enping , Quérat Laurence , Åkerstedt Christina 
Published: May 2016

AbstractPurposeTo evaluate the reliability of intraocular pressure measured by patients with glaucoma themselves using a new hand‐held tonometer and to observe whether the intraocular pressure (IOP) variations have the same pattern on different days while glaucoma treatment is constant.MethodsEighty‐seven patients diagnosed with open‐angle glaucoma or ocular hypertension were recruited to the study. Intraocular pressure measured using Goldmann applanation tonometry (GAT) was compared with IOP measured using tonometry at baseline and on the second visit. Patients measured their IOP at home using the hand‐held tonometers.ResultsThe mean difference between GAT and iCare® values varies from 0 to 1 mmHg. Seventy‐eight per cent of iCare® measurements were within 3 mmHg of the GAT measurements. Approximately 64% of the study eyes had higher IOP in the morning than in the afternoon/evening. Circadian patterns differed between consecutive days in 47% of the study eyes. There were IOP peaks outside office hours in up to 16% of the study eyes.ConclusionMeasurements made using rebound self‐tonometry are accurate and could be used to complement the investigation of patients with glaucoma. Intraocular pressure curves provide valuable data usable when adapting glaucoma treatment.
Clinicians in 25 countries prefer to use lower levels of oxygen to resuscitate preterm infants at birth
Authors: Oei Ju Lee , Ghadge Alpana , Coates Elisabeth , Wright Ian M. , Saugstad Ola D. , Vento Maximo , Buonocore Giuseppe , Nagashima Tatsuo , Suzuki Keiji , Hosono Shiguhero , Davis Peter G. , Craven Paul , Askie Lisa , Dawson Jennifer , Garg Shalabh , Keech Anthony , Rabi Yacov , Smyth John , Sinha Sunil , Stenson Ben , Lui Kei , Hunter Carol Lu , Tarnow Mordi William ,   The HOLISTIC (Higher Or Lower oxygen and Infant Saturation Targeting: International Collaboration) Study Group
Published: May 2016

AbstractAimThis study determined current international clinical practice and opinions regarding initial fractional inspired oxygen (FiO2) and pulse oximetry (SpO2) targets for delivery room resuscitation of preterm infants of less than 29 weeks of gestation.MethodsAn online survey was disseminated to neonatal clinicians via established professional clinical networks using a web‐based survey programme between March 9 and June 30, 2015.ResultsOf the 630 responses from 25 countries, 60% were from neonatologists. The majority (77%) would target SpO2 between the 10th to 50th percentiles values for full‐term infants. The median starting FiO2 was 0.3, with Japan using the highest (0.4) and the UK using the lowest (0.21). New Zealand targeted the highest SpO2 percentiles (median 50%). Most respondents agreed or did not disagree that a trial was required that compared the higher FiO2 of 0.6 (83%), targeting the 50th SpO2 percentile (60%), and the lower FiO2 of 0.21 (80%), targeting the 10th SpO2 percentile (78%). Most (65%) would join this trial. Many considered that evidence was lacking and further research was needed.ConclusionClinicians currently favour lower SpO2 targets for preterm resuscitation, despite acknowledging the lack of evidence for benefit or harm, and 65% would join a clinical trial.
Measuring international business cycles by saving for a rainy day
Authors: Crucini Mario J. , Shintani Mototsugu 
Published: May 2016

AbstractMacroeconomics inevitably begins with a trend‐cycle decomposition of a nation's output. We propose a decomposition in which consumption is the trend component and savings is the cycle component. Using data from the G‐7 plus Australia, we show that this decomposition identifies international business cycles that are: (i) more volatile, (ii) of longer mean duration and (iii) less correlated across countries than the cycle component from the Hodrick‐Prescott filter. We argue that this difference stems from the fact that our method imposes a basic theoretical restriction arising from the permanent income hypothesis similar to the restriction used in Cochrane's decomposition.