bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Reset‐Time Dependent Approach for Stability Analysis of Nonlinear Reset Control Systems
Authors: Ghaffari Valiollah , Karimaghaee Paknosh , Khayatian Alireza 
Published: February 2016

AbstractA reset mechanism in controller can affect the stability property of a closed loop control system. In a simple word, there are stable reset control systems with unstable base‐systems and also unstable reset systems with stable base‐systems. The Lyapunov stability theory is a strong tool to investigate the stability of a nonlinear system. In this paper, based on the well‐known Lyapunov stability concept, some stability conditions for nonlinear reset control systems are addressed. These conditions are dependent on the reset‐times and hence the reset‐time intervals are explicitly emerged in the stability conditions. Some applications of these results are used in numerical examples to show the effectiveness of the proposed approach.
On an Optimized Fuzzy Supervized Multiphase Guidance Law
Authors: Rezaee Mohsen , Seyedtabaii Saeed 
Published: February 2016

AbstractProportional navigation (PN) is an effective guidance law in chasing a constant speed target. However, intercepting a maneuvering target requires extra provisions to contain target acceleration. This is observed in the next generation of guidance laws, namely augmented proportional navigation (APN) and the optimal guidance law (OGL). The other advanced guidance method is integral sliding mode (ISM), which exhibits superb low miss distance (MD), but unfortunately at the cost of disappointing effective lateral acceleration (Ceff), higher than the modest level that APN and OGL demand. Reducing both MD and Ceff can be achieved using a multiphase algorithm. A setup of APN, OGL and ISM is proposed to integrate the strength of each and overcome their weaknesses. Hybrid algorithm smooth management is conducted by an optimally tuned fuzzy supervisory controller. The results indicate that in facing a constant acceleration target, an APN‐ISM twin yields the best results, while in case of a constant jerk target an APN‐OGL‐ISM triplet renders excellent interception. Miss distance as low as 0.012m can be achieved with significantly lower control effort than required by ISM alone. The simulations results confirm the conclusions and illustrate the capacity of the algorithm in combating maneuvering targets.
Formlogik an Brücken – Teil 1
Authors: Kleiser Michael 
Published: February 2016

AbstractBrücken mit kurzen und mittleren Spannweiten werden in den letzten Jahren durchwegs als integrale Bauwerke ohne Fugen und Lager konzipiert. Das zugrunde liegende statische System des Rahmens erfordert ein differenziertes konzeptionelles Vorgehen nicht nur in statisch‐konstruktiven, sondern auch in ästhetischen Belangen. Es werden Anregungen zur Formbildung aufgezeigt, die der innewohnenden Absicht der Bauweise in der entsprechenden Ausformung Geltung verschaffen. Viele Beispiele im Infrastrukturbau zeigen jedoch noch immer Brückentypen, die statisch konstruktiv integral berechnet und konstruktiv ausgebildet sind, jedoch das äußere Erscheinungsbild einer gelagerten bzw. gefügten Brücke vermitteln. Auch vielen Ingenieuren ist der essenzielle Zusammenhang zwischen der rationalen statisch‐konstruktiven Lösung und dem formalen Ausdruck vielfach zu wenig bewusst. Um zu ganzheitlichen und authentischen Entwürfen zu gelangen, muss eine Kohärenz zwischen der Form der Brücke und dem ihr zugrunde liegenden statischen System erkennbar sein. Ziel ist es, Ingenieure von einer ingenieurtechnischen zu einer erweiterten ingeniösen Herangehensweise zu ermutigen, die auch die aus dem statischen System heraus entwickelten formgebenden Aspekte berücksichtigt und letztendlich in der Gesamtheit zu ästhetisch befriedigenden Ergebnissen führen soll. In diesem ersten Aufsatz werden konzeptionelle Überlegungen zur Formbildung im Bereich der Brückenenden erläutert, die die integrale Bauweise auf Basis hergeleiteter Funktionseinheiten reflektieren.Form logic on bridges (Part 1) – Considerations on authentic shaping of integral bridge endsIn recent years bridges with short and medium spans have been designed as integral structures without expansion joints and bearings. The structural system is based on the frame system and requires a differentiated conceptual approach not only in structural but also in aesthetic concerns. In this paper form suggestions are introduced, which provide the inherent intention of the integral structure to the viewer. However, many bridges within the infrastructure are calculated and structurally designed as monolithic structures but have a visual appearance of conventional supported and assembled bridges. Moreover, many engineers are not sufficiently aware of the essential correlation between the rational structural design and its formal expression. In order to achieve holistic and authentic designs, a coherence between the form of the bridge and its underlying structural system must be perceptible. The aim is to encourage engineers from the pure engineer‐technical to an extended ingenious approach that considers form aspects which are developed based on the structural system and ultimately leads to aesthetically satisfactory results. In this first paper, conceptual form considerations for integral bridge ends are discussed, which are based on derived functional units and reflect the integral structural system.
Grünbrückenkonstruktion aus Fertigteil‐Bogensegmenten
Authors: Suffner Andrea , Schulze Torsten 
Published: February 2016

AbstractAufgabe der Grünbrücken ist eine Wiedervernetzung von Lebensräumen, um die Zerschneidungswirkung von Verkehrswegen zu kompensieren.Aus ihrer Funktion heraus sind Grünbrücken in der Regel in ökologisch sensiblen Gebieten erforderlich, die sich im Umkreis stark befahrener Verkehrswege befinden.Die Errichtung einer Grünbrücke bedeutet im Gegensatz zu ihrem Schutzziel einerseits einen starken Eingriff in gerade diesen sensiblen, oftmals geschützten Raum und andererseits eine Beeinträchtigung des Verkehrs der betroffenen Verkehrswege während der Bauzeit. Der Entwurf und der Bau eines Bauwerks in diesem Spannungsfeld werden im Folgenden beschrieben.Green bridges from prefabricated arch‐segmentsGreen bridges aim at relinking habitats to compensate for the dissection effect of traffic routes. Resulting from this function, green bridges are usually needed in ecologically sensitive areas, which are situated in the vicinity of highly frequented traffic routes. Contrary to its protective purpose, the construction of a green bridge on the one hand represents a drastic intervention into these delicate, mostly protected areas and on the other hand a disturbance of traffic on the concerned routes. Considering this area of conflict, the design and construction of a green bridge are described below.
Längskraftabtragung auf Eisenbahnbrücken
Authors: Wenner Marc , Lippert Peter , Plica Sebastian , Marx Steffen 
Published: February 2016

AbstractBeim Entwurf von Eisenbahnbrücken spielt die Wechselwirkung zwischen Gleis und Bauwerk eine maßgebende Rolle. Durch die lückenlose Verlegung der Schiene über längere Tragwerke führen Bewegungen des Überbaus infolge Temperatur, Langzeitverhalten des Betons sowie vertikaler und horizontaler Verkehrslasten zu einer zusätzlichen Beanspruchung der ohnehin schon stark belasteten Schiene. Zur Gewährleistung der Betriebssicherheit müssen daher die in der Schiene auftretenden Kräfte begrenzt werden. Das zu verwendende Rechenmodell sowie die zu führenden Nachweise und die dazugehörigen Grenzwerte sind europaweit im Eurocode EN 1991‐2, Kapitel 6.5.4 geregelt. In Deutschland gilt zusätzlich die DB‐Richtlinie 804.3401. In der praktischen Anwendung kommt es jedoch immer wieder zu Fragen hinsichtlich des Hintergrunds der Modellannahmen sowie der Herkunft der Grenzwerte und der fallbezogenen Anpassung derselben. Die aktuellen Regelungen sind geprägt durch eine lange historische Entwicklung, die vorrangig auf Untersuchungen in Deutschland basiert. Im folgenden Teil 1 des Beitrags sollen die Geschichte des lückenlosen Gleises und die Entwicklung der Betrachtung des Zusammenwirkens zwischen Schiene und Brücke vorgestellt werden. Zusätzlich werden das Modell und die Annahmen, auf denen es beruht, präsentiert. Im Teil 2 werden dann die Hintergründe des Nachweises und der zugehörigen, im Regelwerk verankerten Grenzwerte erläutert.Track‐bridge‐interaction – Part 1: historical development and modelIn order to guarantee improved driving dynamics and comfort for railway passengers, it is common today to weld rails to a continuously track. However, viaducts constitute singularities in the railway substructure. Under thermal variations, creep, shrinkage, train passage and braking, the bridge structure deforms and leads to additional solicitation of the rail. The track‐bridge interaction becomes a decisive criterion in railway bridge design. The forces in the rail must be limited in order to guarantee the safety of the traffic. The calculation model as well as the verification schema is regulated in the Eurocode EN 1991‐2, chapter 6.5.4 and in Germany additionally in the Richtlinie 804. However, the backgrounds of the model assumptions and of the stress limits, which are necessary for the understanding of the calculations, are very poor documented. In the part 1 of this article, the history of the continuous welded rail and the development of the investigation of track‐bridge interaction effects will be presented. Additionally, the model as well as the assumptions for the calculation will be presented. In the part 2, the backgrounds of the verification procedure and of its limits will be explained.
Zur praktischen Anwendung des Sicherheitskonzepts nach EC3 bei der Bemessung von Tragseilen
Authors: Gugeler Jochen 
Published: February 2016

AbstractDas Sicherheitskonzept der DIN EN 1993‐1‐11 für die Bemessung und Konstruktion von Zuggliedern aus Stahl führt gegenüber den bisherigen Regelungen bei Seiltragwerken, die gegen Steifigkeit vorgespannt werden, zu deutlich größeren und damit unwirtschaftlicheren Querschnitten von Seilen und Anschlussdetails. Im folgenden Artikel soll deshalb hinterfragt werden, ob die gewählten Bemessungsansätze für diesen Typ von vorgespannten Seiltragwerken sinnvoll und notwendig sind.Some remarks concerning the application of the safety concept according to EC3 for the design of steel cablesCompared with the former regulations for cable structures that are prestressed against stiffness, the safety concept of DIN EN 1993‐1‐11 for design and construction of steel tension members results in larger and less economic cross sections for cables and clamps. The following text debates the question whether the use of this design concept is reasonable for all types of cable structures.
Congenital anomalies of the kidney and the urinary tract: A murmansk county birth registry study
Authors: Postoev Vitaly A. , Grjibovski Andrej M. , Kovalenko Anton A. , Anda Erik Eik , Nieboer Evert , Odland Jon Øyvind 
Published: February 2016

BACKGROUNDCongenital anomalies of the kidney and the urinary tract (CAKUTs) are relatively common birth defects. The combined prevalence in Europe was 3.3 per 1000 in 2012. The risk factors for these anomalies are not clearly identified. The aims of our study were to calculate the birth prevalences of urinary malformations in Murmansk County during 2006 to 2011 and to investigate related prenatal risk factors.METHODSThe Murmansk County Birth Registry was the primary source of information and our study included 50,936 singletons in the examination of structure, prevalence and proportional distribution of CAKUTs. The multivariate analyses of risk factors involved 39,322 newborns.RESULTSThe prevalence of CAKUTs was 4.0 per 1000 newborns (95% confidence interval [CI], 3.4–4.5) and did not change during the study period. The most prevalent malformation was congenital hydronephrosis (14.2% of all cases). Diabetes mellitus or gestational diabetes (odds ratio [OR] = 4.77; 95% CI, 1.16–19.65), acute infections while pregnant (OR = 1.83; 95% CI, 1.14–2.94), the use of medication during pregnancy (OR = 2.03; 95% CI, 1.44–2.82), and conception during the summer (OR = 1.75; 95% CI 1.15–2.66) were significantly associated with higher risk of CAKUTs.CONCLUSIONThe overall fourfold enhancement of the occurrence of urinary malformations in Murmansk County for the 2006 to 2011 period showed little annual dependence. During pregnancy, use of medications, infections, pre‐existing diabetes mellitus, or gestational diabetes were associated with increased risk of these anomalies, as was conception during summer. Our findings have direct applications in improving prenatal care in Murmansk County and establishing targets for prenatal screening and women's consultations. Birth Defects Research (Part A) 106:185–193, 2016. © 2016 Wiley Periodicals, Inc.
Multiway analysis applied to time‐resolved chemiluminescence for simultaneous determination of paracetamol and codeine in pharmaceuticals
Authors: Mokhtari Ali , Jafari Delouei Nastaran , Keyvanfard Mohsen , Abdolhosseini Mohammad 
Published: February 2016

AbstractThis method is based on the enhancing effect of codeine (COD) and paracetamol (PAR) on the chemiluminescence (CL) reaction of Ru(phen)32+ with Ce(IV). In the batch mode, COD gives a relatively sharp peak with the highest CL intensity at 4.0 s, whereas the maximum CL intensity of the PAR appears at ~60 s after injection of Ce(IV) solution. Whole CL time profiles allowed use of the time‐resolved CL data in combination with multiway calibration techniques, as multiway partial least squares (N‐PLS), for the quantitative determination of both COD and PAR in binary mixtures. In this work, we found that the impact of Ce(IV) concentration on the CL intensity was different for COD and PAR. Therefore, a Ce(IV) concentration mode was added to the time and sample modes to obtain 3D data. The percent relative standard deviation (%RSD) values for 10 determinations of 1.0 × 10−5 mol/L of COD and 1.0 × 10−4 mol/L of PAR were 6.1% and 8.7%, respectively. The limit of detection (LOD) values (S/N = 3) were 0.9 × 10−8 mol/L and 1.0 × 10−6 mol/L for COD and PAR, respectively. The proposed method was successfully applied to the determination of PAR and COD in commercial pharmaceutical formulations. Acceptable recoveries (90–110%) were obtained for the quantification of these drugs in the real samples. Copyright © 2016 John Wiley & Sons, Ltd.
Luminescence properties of novel deep‐red‐emitting Ca3Al2Ge2O10:Cr3+ phosphors
Authors: Bai Qiongyu , Wang Zhijun , Li Panlai , Li Ting , Xu Shuchao , Yang Zhiping 
Published: February 2016

AbstractCa3Al2Ge2O10:Cr3+ phosphors were prepared by a high‐temperature solid‐state method, and their luminescence properties were investigated. Under excitation at 550 nm, Ca3Al2Ge2O10:Cr3+ phosphors exhibited a broad red emission band at 697 nm in the range 650–750 nm that was caused by the 2E→4A2 transition of Cr3+. For the 697 nm emission peak, emission intensity reached a maximum at x = 0.07, and there was concentration quenching of Cr3+ in Ca3Al2Ge2O10; the corresponding concentration quenching mechanism was analysed. Under excitation at 262 nm, the Ca3Al2Ge2O10:Cr3+ phosphor showed a weakly broad emission band in the range 350–600 nm that was caused by intrinsic defects (V′′Ca and V′′O). Copyright © 2016 John Wiley & Sons, Ltd.
Invited review: MnmE, a GTPase that drives a complex tRNA modification reaction
Authors: Fislage Marcus , Wauters Lina , Versées Wim 
Published: February 2016

ABSTRACTMnmE is a multi‐domain GTPase that is conserved from bacteria to man. Together with its partner protein MnmG it is involved in the synthesis of a tRNA wobble uridine modification. The orthologues of these proteins in eukaryotes are targeted to mitochondria and mutations in the encoding genes are associated with severe mitochondrial diseases. While classical small GTP‐binding proteins are regulated via auxiliary GEFs and GAPs, the GTPase activity of MnmE is activated via potassium‐dependent homodimerization of its G domains. In this review we focus on the catalytic mechanism of GTP hydrolysis by MnmE and the large scale conformational changes that are triggered throughout the GTPase cycle. We also discuss how these conformational changes might be used to drive and tune the complex tRNA modification reaction. © 2016 Wiley Periodicals, Inc. Biopolymers 105: 568–579, 2016.
Diminished oligomerization in the synthesis of new anti‐angiogenic cyclic peptide using solution instead of solid‐phase cyclization
Authors: Rubio Sandra , Clarhaut Jonathan , Péraudeau Elodie , Vincenzi Marian , Soum Claire , Rossi Filomena , Guillon Jean , Papot Sébastien , Ronga Luisa 
Published: February 2016

ABSTRACTThe design and synthesis of novel peptides that inhibit angiogenesis is an important area for anti‐angiogenic drug development. Cyclic and small peptides present several advantages for therapeutic application, including stability, solubility, increased bio‐availability and lack of immune response in the host cell. We describe here the synthesis and biological evaluations of a new cyclic peptide analog of CBO‐P11: cyclo(RIKPHE), designated herein as CBO‐P23M, a hexamer peptide encompassing residues 82 to 86 of VEGF which are involved in the interaction with VEGF receptor‐2. CBO‐P23M was prepared using in solution cyclization, therefore reducing the peptide cyclodimerization occurred during solid‐phase cyclization. The cyclic dimer of CBO‐P23M, which was obtained as the main side product during synthesis of the corresponding monomer, was also isolated and investigated. Both peptides markedly reduce VEGF‐A‐induced phosphorylation of VEGFR‐2 and Erk1/2. Moreover, they exhibit anti‐angiogenic activity in an in vitro morphogenesis study. Therefore CBO‐P23M and CBO‐P23M dimer appear as attractive candidates for the development of novel angiogenesis inhibitors for the treatment of cancer and other angiogenesis‐related diseases. © 2016 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 368–375, 2016.
miR‐708/LSD1 axis regulates the proliferation and invasion of breast cancer cells
Authors: Ma Lin , Ma Shan , Zhao Guimei , Yang Longqiu , Zhang Peng , Yi Qingting , Cheng Shuguang 
Published: February 2016

AbstractBreast cancer is one of the most common malignant tumors in women worldwide. The microRNAs (miRNAs) are small, noncoding RNAs that regulate various biological processes, including breast cancer. miR‐708 played an important role in a variety of cancers. However, its involvement in breast cancer remains largely unclear. In this study, we found that forced the expression of miR‐708 in breast cancer cell lines decreased cell proliferation and invasion, whereas inhibition of miR‐708 increased cell growth and invasion. miR‐708 could directly target the LSD1 3′UTR to downregulate the expression. Further studies suggested that inhibition of LSD1 could phenocopied function of the miR‐708 overexpression in MDA‐MB‐231 cells .Overexpression of LSD1 could counteract the effects of miR‐708 on the proliferation and invasion. Taken together, the results indicate that miR‐708 may function as a tumor suppressor gene in breast cancer development, and miR‐708/LSD1 axis may be a therapeutic intervention in breast cancer in the future.
Heterotopic pregnancy with natural conception; a rare event that is still being misdiagnosed: a case report
Authors: Fatema Nishat , Al Badi Muna Mubarak , Rahman Mahin , Elawdy Mohamed M. 
Published: February 2016

Key Clinical MessageSimultaneous presence of intra‐ and extra‐uterine pregnancies have been known as heterotopic pregnancy (HP); the condition which is extremely rare with natural conception. Our aim is to increase the obstetrician's awareness to increase the level of positive outcome in such rare events.
Bipolar Electrochemical Approach with a Thin Layer of Supporting Electrolyte towards the Growth of Self‐Organizing TiO2 Nanotubes
Authors: Saqib Muhammad , Lai Jianping , Zhao Jianming , Li Suping , Xu Guobao 
Published: February 2016

AbstractThe front cover artwork is provided by the group of Prof. Guobao Xu at State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences (http://people.gucas.ac.cn/∼guobaoxu?language=en). The image shows the bipolar electrochemical approach with a thin layer of supporting electrolyte towards the growth of self‐organizing TiO2 nanotubes in a horizontal direction for single and multiple samples in a single wireless run with tunable diameters. Read the full text of the Communication at 10.1002/celc.201500182.
Synthesis and Photophysical Studies of Calixarene‐Based Alkynylplatinum(II) Terpyridine Complexes with Various Receptor Sites for Colorimetric and Luminescence Sensing of Anions
Authors: Hau Franky Ka‐Wah , Lo Hiu‐Suet , Yam Vivian Wing‐Wah 
Published: February 2016

AbstractA series of mononuclear and dinuclear platinum(II) terpyridine complexes with amide‐, sulfonamide‐, and urea‐containing ligands (1–9) has been successfully designed and synthesized, and their photophysical and anion‐binding properties have been studied. The anion‐binding properties of the complexes were studied by electronic absorption, emission, and 1H NMR spectroscopy. Upon the binding with anions, the dinuclear complexes 1–3 exhibit large electronic absorption and emission spectral changes, while for the mononuclear analogues 4–6 much smaller spectral changes were observed. Interesting colorimetric responses towards different anions were observed in dinuclear complexes 1–3. Dinuclear complexes 7–9 are found to be insensitive to anion‐binding, which could be attributed to the presence of intramolecular Pt⋅⋅⋅Pt interactions and/or π–π stacking in the complexes that led to the reduced anion‐binding affinity.
Construction of a 2D Graphene‐Like MoS2/C3N4 Heterojunction with Enhanced Visible‐Light Photocatalytic Activity and Photoelectrochemical Activity
Authors: Yan Jia , Chen Zhigang , Ji Haiyan , Liu Zheng , Wang Xin , Xu Yuanguo , She Xiaojie , Huang Liying , Xu Li , Xu Hui , Li Huaming 
Published: February 2016

AbstractA novel graphene‐like MoS2/C3N4 (GL‐MoS2/C3N4) composite photocatalyst has been synthesized by a facile ethylene glycol (EG)‐assisted solvothermal method. The structure and morphology of this GL‐MoS2/C3N4 photocatalyst have been investigated by a wide range of characterization methods. The results showed that GL‐MoS2 was uniformly distributed on the surface of GL‐C3N4 forming a heterostructure. The obtained composite exhibited strong absorbing ability in the ultraviolet (UV) and visible regions. When irradiated with visible light, the composite photocatalyst showed high activity superior to those of the respective individual components GL‐MoS2 and GL‐C3N4 in the degradation of methyl orange. The enhanced photocatalytic activity of the composite may be attributed to the efficient separation of electron–hole pairs as a result of the matching band potentials between GL‐MoS2 and GL‐C3N4. Furthermore, a photocatalytic mechanism for the composite material has been proposed, and the photocatalytic reaction kinetics has been measured. Moreover, GL‐MoS2/C3N4 could serve as a novel sensor for trace amounts of Cu2+ since it exhibited good selectivity for Cu2+ detection in water.