bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study of correlation between investor sentiment and stock market based on Copula model
Authors: Yao Can Zhong , Sun Bo Yi , Lin Ji Nan 
Published: March 2017

Purpose
This paper aims to capture tail dependence between sentiment index and Shanghai composite index (SCI) by proposing a sentiment index based on text mining.

Design/methodology/approach
Online text mining and the Copula model were used in this study.

Findings
First, the paper finds herding effect in the expression of investors’ sentiment from online text data, and the usage occurrence frequency of most vocabulary is less correlative with SCI. Second, given these two features, the paper uses weighted divide-and-conquer algorithm to construct a sentiment index. Finally, because of multivariate non-Gaussian joint distribution between them, the paper uses the Copula model to detect their tail dependences, and finds that both upper and lower tail dependences could have a significant influence between positive sentiment and SCI, with a higher probability on the upper one. Additionally, only the upper tail dependence exhibits the significant influence between negative sentiment and SCI.

Originality/value
This paper proposes a framework of constructing investment sentiment index with the weighted conquer-and-divide algorithm, and characterizes tail dependence between sentiment index and SCI. The implication can measure the environment of investment market of China and provide an empirical ground for bandwagon effect and bargain shopper effect.
Wiener and Luhmann on feedback: from complexity to sustainability
Authors: Valentinov Vladislav 
Published: March 2017

Purpose
The rise of the general systems theory in the twentieth century would not have been possible without the concept of feedback. Of special interest to the present paper is Niklas Luhmann’s reconstruction and critique of Wiener’s cybernetic approach to the feedback concept. Luhmann has suggested that the operation of the feedback-controlled systems potentially poses problems of sustainability. The purpose of this paper is to explore this suggestion in more detail.

Design/methodology/approach
The reconstruction of the arguments of Luhmann and Wiener shows that both scholars approached the feedback concept from the “system-environment” perspective. Luhmann takes system-environment relations to be inherently precarious. Wiener underscores the importance of the sensitivity of the feedback-controlled systems to their environment.

Findings
Drawing on Norbert Wiener’s and Niklas Luhmann’s ideas, the paper shows that every specification of the feedback mechanism implies the drawing of the moral boundary that demarcates those parts of the environment to which the relevant system is sensitive from those to which it is not. A likely outcome of this boundary drawing is the maintenance of intra-systemic complexity at the cost of the deteriorating sustainability of the system in its environment.

Originality/value
Until today, the general system theory has sought to explain organized complexity and rightly underscored the role of feedback in maintaining it, thereby inadvertently creating the chasm between the complexity and sustainability dimensions of human civilization. The present paper pleads for reorienting of the systems-theoretic analysis of the feedback concept toward closing this chasm.
Corporate social responsibility and conflicts of interest in the alcohol and gambling industries: a post‐political discourse?
Authors: Geiger Ben Baumberg , Cuzzocrea Valentina 
Published: March 2017

AbstractThe corporate pursuit of social goals – known as Corporate Social Responsibility or ‘CSR’ – has been subject to critique on a number of grounds. However, a hitherto underexplored potential consequence of CSR has been suggested in a recent paper by C. Garsten and K. Jacobsson (‘Post‐Political Regulation: Soft Power and Post‐political Visions in Global Governance’ (2013), Critical Sociology 39: 421–37). They suggest that CSR is part of an international trend towards ‘post‐political’ governance discourses, where an emphasis on different actors’ common goals obscures conflicts of interest, subverting the open political conflict necessary for a well‐functioning democracy. This paper examines whether such post‐political discourses – including an outright denial of conflict of interest – can be found within the alcohol and gambling industries, where conflicts of interest are likely to be particularly acute given the addictive nature of the goods/services in question. Based on interviews with CSR professionals in these industries in Italy, the UK, and at EU‐level, we do indeed find evidence of a post‐political discourse. In these discourses, alcohol/gambling industry staff deny potential conflicts of interest on the basis that any small benefits from sales to a small number of addicts are seen to be outweighed by the reputational damage that addicts cause. Crucially, however, this coexists with another, less post‐political discourse, where addictions CSR professionals emphasize ‘common ground’ as a basis for CSR, while accepting some instances of possible conflict of interest. Here interviewees make considerable efforts to differentiate good (sustainable) from bad (short‐term) self‐interest in order to stress the genuineness of their own actions. We conclude the paper by considering whether CSR embedded within a ‘common ground’ discourse still hides conflicts of interests and subverts democratic debate, or overcomes the problems identified by Garsten and Jacobsson.
Obstetrical and perinatal complications of twin pregnancies: is there a link with the type of infertility treatment?
Authors: Deltombe‐Bodart Sophie , Deruelle Philippe , Drumez Elodie , Cordiez Sophie , Catteau‐Jonard Sophie , Garabedian Charles 
Published: March 2017

AbstractIntroductionThe aim of this study was to compare the maternal and perinatal data from spontaneous twin pregnancies with twin pregnancies conceived via assisted reproductive technology, and to evaluate the outcomes depending on the type of treatment.Material and methodsA historical cohort of all twin live births between 1997 and 2014 was used to create two groups: spontaneous pregnancies and pregnancies after infertility treatment (ovulation induction, intrauterine insemination, in vitro fertilization, and intracytoplasmic sperm injection). The population characteristics and pregnancy, childbirth, and neonatal complications were compared, and the data were adjusted for age, parity, chorionicity, and the mother's body mass index to assess only the impact of the infertility treatments.ResultsIn total, 1580 twin pregnancies were included, with 575 requiring assisted conception. We did not observe any differences between the assisted conception pregnancies and the spontaneous twin pregnancies with regard to the obstetric and childbirth complications and neonatal outcomes. In addition, there were no statistically significant differences between the types of infertility treatment.ConclusionAfter adjusting for the maternal parameters and chorionicity, the twin pregnancies conceived via assisted reproductive technology were not at an increased risk of obstetric and neonatal complications. Moreover, the type of treatment did not alter the obstetric and neonatal complications. Therefore, the higher complication rate was related to the patient's medical specifics, rather than to the infertility treatment.
Cerebral oxygenation as measured by near‐infrared spectroscopy in neonatal intensive care: correlation with arterial oxygenation
Authors: Hunter Carol Lu , Oei Ju Lee , Lui Kei , Schindler Timothy 
Published: March 2017

AbstractAimTo assess correlation between cerebral oxygenation (rScO2), as measured by near‐infrared spectroscopy (NIRS), and arterial oxygenation (PaO2), as measured by arterial blood gases, in preterm neonates.MethodsPreterm neonates <37 weeks gestation with an indwelling arterial vascular catheter were recruited between April and August 2015 from the neonatal intensive care unit of the Royal Hospital for Women, Randwick NSW, Australia. The NIRS sensor was placed on the frontolateral aspect of the head prior to arterial gas sampling. NIRS, blood gas and clinical observation data were analysed using mixed linear modelling.ResultsTwenty‐two neonates between 24 and 31 weeks gestation (mean 27.6 weeks) were recruited, and 75 readings obtained. No significant correlation was identified between cerebral oxygenation (rScO2) and arterial oxygenation (PaO2) (p = 0.37). There was also no significant correlation between rScO2 and clinically relevant parameters of SaO2 (p = 0.06), SpO2 (p = 0.44) and PaCO2 (p = 0.79).ConclusionThis study did not demonstrate any correlation between NIRS values and arterial oxygenation in clinically stable preterm infants. These results highlight some of the difficulties in clinical interpretation of NIRS values in neonatal intensive care, and further evaluation is needed to determine the applicability of NIRS to management of preterm infants.
Rigid catheters reduced duration of less invasive surfactant therapy procedures in manikins
Authors: Rigo V , Debauche C , Maton P , Broux I , Van Laere D 
Published: March 2017

AbstractAimDifferent catheters can be used for less invasive surfactant therapy (LIST): feeding tubes inserted with or without Magill forceps, different angiocatheters and centre specific devices, such as umbilical catheters affixed to a stylet. This study compared the effectiveness of LIST devices and endotracheal tubes (ETT).MethodsVideo recordings of 20 neonatologists simulating different LIST techniques on two manikin heads were analysed. Procedural effectiveness was evaluated by the duration of procedures and failure rates. Ease of use was scored.ResultsThe median procedure time for the Neonatal Intubation Trainer was significantly longer with feeding tubes without Magill forceps. For the more difficult ALS Baby Trainer, successful procedures lasted a median of 24 (17–32) seconds with ETT, 24 (15–36) seconds with stylet‐guided catheters and 34 (27–46) seconds and 37 (29–42) seconds with 13‐cm and 30‐cm angiocatheters, respectively. Both methods using feeding tubes were statistically slower than ETT intubation, lasting 32 (25–44) seconds and 39 (27–95) seconds with or without Magill forceps. Failure rates (7–20%) were no different between the LIST methods. Techniques using feeding tubes were rated as more difficult.ConclusionOnly rigid or stylet‐guided catheters required tracheal catheterisation times similar to those of endotracheal intubation and neonatologists found them easier.
Effects of melatonin on maturation, histone acetylation, autophagy of porcine oocytes and subsequent embryonic development
Authors: Chen Zhen , Zuo Xiaoyuan , Li Hui , Hong Renyun , Ding Biao , Liu Chengxue , Gao Di , Shang Hui , Cao Zubing , Huang Weiping , Zhang Xiaorong , Zhang Yunhai 
Published: March 2017

AbstractMelatonin (MLT) is an endogenous hormone with roles in animal germ cell development. However, the effect of MLT on porcine oocyte maturation and its underlying mechanisms remain largely unknown. Here, we investigated the effects of exogenous MLT on oocyte maturation, histone acetylation, autophagy and subsequent embryonic development. We found that 1 nmol/L MLT supplemented in maturation medium was the optimal concentration to promote porcine oocyte maturation and subsequent developmental competence and quality of parthenogenetic embryos. Interestingly, the beneficial effects of 1 nmol/L MLT treatment on porcine oocyte maturation and embryo development were mainly attributed to the first half period of in vitro maturation. Simultaneously, MLT treatment could also improve maturation of small follicle‐derived oocytes, morphologically poor (cumulus cell layer ≤1) and even artificially denuded oocytes and their subsequent embryo development. Furthermore, MLT treatment not only could decrease the levels of H3K27ac and H4K16ac in metaphase II (MII) oocytes, but also could increase the expression abundances of genes associated with cumulus cell expansion, meiotic maturation, histone acetylation and autophagy in cumulus cells or MII oocytes. These results indicate that MLT treatment can facilitate porcine oocyte maturation and subsequent embryonic development probably, through improvements in histone acetylation and autophagy in oocytes.
Allogeneic stem cell transplantation in patients with atypical chronic myeloid leukaemia: a retrospective study from the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation
Authors: Onida Francesco , de Wreede Liesbeth C. , van Biezen Anja , Eikema Diderik‐Jan , Byrne Jenny L. , Iori Anna P. , Schots Rik , Jungova Alexandra , Schetelig Johannes , Finke Jürgen , Veelken Hendrik , Johansson Jan‐Erik , Craddock Charles , Stelljes Matthias , Theobald Matthias , Holler Ernst , Schanz Urs , Schaap Nicolaas , Bittenbring Jörg , Olavarria Eduardo , Chalandon Yves , Kröger Nicolaus 
Published: March 2017

SummaryAtypical chronic myeloid leukaemia (aCML) is an aggressive malignancy for which allogeneic haematopoietic stem cell transplantation (allo‐HSCT) represents the only curative option. We describe transplant outcomes in 42 patients reported to the European Society for Blood and Marrow Transplantation (EBMT) registry who underwent allo‐HSCT for aCML between 1997 and 2006. Median age was 46 years. Median time from diagnosis to transplant was 7 months. Disease status was first chronic phase in 69%. Donors were human leucocyte antigen (HLA)‐identical siblings in 64% and matched unrelated (MUD) in 36%. A reduced intensity conditioning was employed in 24% of patients. T‐cell depletion was applied in 87% and 26% of transplants from MUD and HLA‐identical siblings, respectively. According to the EBMT risk‐score, 45% of patients were ‘low‐risk’, 31% ‘intermediate‐risk’ and 24% ‘high‐risk’. Following allo‐HSCT, 87% of patients achieved complete remission. At 5 years, relapse‐free survival was 36% and non‐relapse mortality (NRM) was 24%, while relapse occurred in 40%. Patient age and the EBMT score had an impact on overall survival. Relapse‐free survival was higher in MUD than in HLA‐identical sibling HSCT, with no difference in NRM. In conclusion, this study confirmed that allo‐HSCT represents a valid strategy to achieve cure in a reasonable proportion of patients with aCML, with young patients with low EBMT risk score being the best candidates.
Predictive value of the 2014 International Society of Urological Pathology grading system for prostate cancer in patients undergoing radical prostatectomy with long‐term follow‐up
Authors: Grogan Judith , Gupta Ruta , Mahon Kate L. , Stricker Phillip D. , Haynes Anne‐Maree , Delprado Warick , Turner Jennifer , Horvath Lisa G. , Kench James G. 
Published: March 2017

ObjectiveTo assess the relationship between the International Society of Urological Pathology (ISUP) 2014 grading system, biochemical recurrence (BCR) and clinical recurrence (CLR) after radical prostatectomy (RP), to determine whether the 2014 ISUP grading system is a better predictor of survival compared with the previous Gleason scoring systems, and to investigate whether incorporation of the tertiary pattern/grade into the ISUP scoring system significantly improves its efficacy.Patients and MethodsA total of 635 RP cases (1991–1999) were identified from a database at a single institution. A histopathology review was performed to re‐grade the cases as per the ISUP 2014 grading system. All relevant clinicopathological data and clinical follow‐up (median [range] 15.25 [0.3–26] years) were obtained. Log‐rank, Kaplan–Meier, Cox regression and Harrell's concordance c‐indices analyses were performed.ResultsAt a median follow‐up of 15 years, 276 patients (44%) had BCR and 41 (7%) had CLR. Grade Groups 1, 2, 3, 4 and 5 were seen in 112 (18%), 307 (48%), 129 (20%), 33 (5%) and 54 patients (9%), respectively: 337 (53%) were upgraded, while 70 (11%) were downgraded compared with the 1992 Gleason system. Grade Group (hazard ratio [HR] 4.9; P < 0.001) and preoperative prostate‐specific antigen (PSA) level (HR 1.4; P < 0.001) were independent predictors of BCR. Only Grade Group 5 (HR 12.3; P = 0.02), preoperative PSA (HR 1.6; P < 0.001), stage pT3b (HR 3.1; P = 0.03) and pT4 (HR 12.4; P < 0.001) independently predicted CLR. Harrell's c‐indices showed that the 2014 ISUP grading system was a significantly better predictor of BCR and CLR as well as prostate cancer‐specific death, compared with the 2005 ISUP modified Gleason system. The replacement of the secondary pattern by the tertiary pattern did not alter the prognostic efficacy of the ISUP 2014 grading system.ConclusionsThe ISUP 2014 grading system is a significant independent predictor of both BCR and CLR, outperforming the 2005 ISUP modified Gleason system. This classification system has the potential to influence clinical decision‐making after RP.
Propofol induces excessive vasodilation of aortic rings by inhibiting protein kinase Cβ2 and θ in spontaneously hypertensive rats
Authors: Wang Yan , Zhou Quanhong , Wu Bin , Zhou Huixuan , Zhang Xiaoli , Jiang Wei , Wang Li , Wang Aizhong 
Published: March 2017

Background and PurposeExaggerated hypotension following administration of propofol is strongly predicted in patients with hypertension. Increased PKCs play a crucial role in regulating vascular tone. We studied whether propofol induces vasodilation by inhibiting increased PKC activity in spontaneously hypertensive rats (SHRs) and, if so, whether contractile Ca2+ sensitization pathways and filamentous–globular (F/G) actin dynamics were involved.Experimental ApproachRings of thoracic aorta, denuded of endothelium, from normotensive Wistar‐Kyoto (WKY) rats and SHR were prepared for functional studies. Expression and activity of PKCs in vascular smooth muscle (VSM) cells were determined by Western blot analysis and elisa respectively. Phosphorylation of the key proteins in PKC Ca2+ sensitization pathways was also examined. Actin polymerization was evaluated by differential centrifugation to probe G‐ and F‐actin content.Key ResultsBasal expression and activity of PKCβ2 and PKCθ were increased in aortic VSMs of SHR, compared with those from WKY rats. Vasorelaxation of SHR aortas by propofol was markedly attenuated by LY333531 (a specific PKCβ inhibitor) or the PKCθ pseudo‐substrate inhibitor. Furthermore, noradrenaline‐enhanced phosphorylation, and the translocation of PKCβ2 and PKCθ, was inhibited by propofol, with decreased actin polymerization and PKCβ2‐mediated Ca2+ sensitization pathway in SHR aortas.Conclusion and ImplicationsPropofol suppressed increased PKCβ2 and PKCθ activity, which was partly responsible for exaggerated vasodilation in SHR. This suppression results in inhibition of actin polymerization, as well as that of the PKCβ2‐ but not PKCθ‐mediated, Ca2+ sensitization pathway. These data provide a novel explanation for the unwanted side effects of propofol.
High School Dropout in Proximal Context: The Triggering Role of Stressful Life Events
Authors: Dupéré Véronique , Dion Eric , Leventhal Tama , Archambault Isabelle , Crosnoe Robert , Janosz Michel 
Published: March 2017

Adolescents who drop out of high school experience enduring negative consequences across many domains. Yet, the circumstances triggering their departure are poorly understood. This study examined the precipitating role of recent psychosocial stressors by comparing three groups of Canadian high school students (52% boys; Mage = 16.3 years; N = 545): recent dropouts, matched at‐risk students who remain in school, and average students. Results indicate that in comparison with the two other groups, dropouts were over three times more likely to have experienced recent acute stressors rated as severe by independent coders. These stressors occurred across a variety of domains. Considering the circumstances in which youth decide to drop out has implications for future research and for policy and practice.
Guided bone regeneration of non‐contained mandibular buccal bone defects using deproteinized bovine bone mineral and a collagen membrane: an experimental in vivo investigation
Authors: Sanz Mariano , Ferrantino Luca , Vignoletti Fabio , de Sanctis Massimo , Berglundh Tord 
Published: March 2017

AbstractAimThe aim of this pre‐clinical in vivo study was to analyse different stages of wound healing after guided bone regeneration in non‐contained mandibular buccal bone defects.Materials and methodsEighteen female beagle dogs, between 1.5 and 2 years old, were used. Buccal bone defects were created in the mandible following extraction of the mesial roots of M1, P4, the distal root of P3 and booth roots of P2. Augmentation procedures of the healed defects were performed 3 months later using a bone replacement graft (T1), an absorbable collagen membrane (T2) or a combination of both procedures (T3). Using a randomized block study design, four stages of healing in two groups of dogs were examined (4 days, 2, 6 weeks and 3 months). The animals were euthanized, and biopsies obtained at the end of each of the study periods were prepared for histological examination.ResultsThe different reconstructive procedures resulted in regenerated tissue compartments of varying size that contained newly formed bone, non‐mineralized tissue and bone augmentation biomaterial when a bone replacement graft was used. While the proportions of mineralized tissue increased and non‐mineralized tissue decreased over time in the three groups, the changes in proportions of the DBBM material were small. Initial defect depth, healing time and treatment group significantly influenced the percentage of mineralized tissue obtained. The multivariate multilevel analysis showed that significantly larger area proportions of mineralized tissue were obtained when the T2 sites were compared with T1 and T3 sites, what highlights the importance of the barrier membrane effect for attaining new bone formation. Only in the larger size defects (M1) total ROI at T3 and T1 sites was significantly larger than at T2, what highlights the importance of using a bone replacement graft as a space maintenance scaffold.ConclusionIt is suggested that healing following augmentation of non‐contained buccal bone defects was characterized by a gradual shift in the relative proportions of non‐mineralized and mineralized tissue components.