bluuebunny/crossref_metadata_2025_split huggingface dataset:
&lt;i&gt;PSAP&lt;/i&gt; gene variants and haplotypes reveal significant effects on carcass and meat quality traits in Chinese Simmental-cross cattle
Authors: Guo Pengcheng , Zhao Zhihui , Yan Shouqing , Li Junya , Xiao Hang , Yang Dongxue , Zhao Yaolu , Jiang Ping , Yang Runjun 
Published: November 2016

Abstract. Prosaposin (PSAP) is the precursor protein of four small lysosomal glycoproteins and plays vital roles in muscle growth and development of beef cattle. The aim of this study is to evaluate the association between PSAP gene polymorphisms with carcass composition and meat quality traits of Chinese Simmental-cross cattle. In the present study, six SNPs were identified within intron 10 and exon 11 of the PSAP gene from 380 beef cattle by direct DNA sequencing, and 47 traits of carcass composition and meat quality were measured in the studied population. Then, the relationship between variants of PSAP gene with economic traits was analyzed using statistical methods. The result revealed that I10-65G  >  A, I10-313C  >  T, E11-87C  >  T, and E11-93C  >  G were significantly associated with carcass traits, such as dressing percentage, fat coverage rate, carcass depth, and hind leg width, and I10-162C  >  T and I10-274C  >  T were significantly associated with marbling score traits. In addition, the individuals with GCCCGC haplotype showed significant higher dressed weight, dressing percentage and rib eye area (p <  0.01), and the individuals with ACCTCC haplotype showed a significant association with the pH of beef and backfat thickness in the cattle population (p <  0.05). Our results indicate that these SNPs and haplotypes of the PSAP gene are possible important genetic factors that influence carcass composition and meat quality traits, and they may be useful markers in future marker-assisted selection (MAS) programs in beef cattle breeding and production.
Benchmark levels for the consumptive water footprint of crop production for different environmental conditions: a case study for winter wheat in China
Authors: Zhuo La , Mekonnen Mesfin M. , Hoekstra Arjen Y. 
Published: November 2016

Abstract. Meeting growing food demands while simultaneously shrinking the water footprint (WF) of agricultural production is one of the greatest societal challenges. Benchmarks for the WF of crop production can serve as a reference and be helpful in setting WF reduction targets. The consumptive WF of crops, the consumption of rainwater stored in the soil (green WF), and the consumption of irrigation water (blue WF) over the crop growing period varies spatially and temporally depending on environmental factors like climate and soil. The study explores which environmental factors should be distinguished when determining benchmark levels for the consumptive WF of crops. Hereto we determine benchmark levels for the consumptive WF of winter wheat production in China for all separate years in the period 1961–2008, for rain-fed vs. irrigated croplands, for wet vs. dry years, for warm vs. cold years, for four different soil classes, and for two different climate zones. We simulate consumptive WFs of winter wheat production with the crop water productivity model AquaCrop at a 5 by 5 arcmin resolution, accounting for water stress only. The results show that (i) benchmark levels determined for individual years for the country as a whole remain within a range of ±20 % around long-term mean levels over 1961–2008, (ii) the WF benchmarks for irrigated winter wheat are 8–10 % larger than those for rain-fed winter wheat, (iii) WF benchmarks for wet years are 1–3 % smaller than for dry years, (iv) WF benchmarks for warm years are 7–8 % smaller than for cold years, (v) WF benchmarks differ by about 10–12 % across different soil texture classes, and (vi) WF benchmarks for the humid zone are 26–31 % smaller than for the arid zone, which has relatively higher reference evapotranspiration in general and lower yields in rain-fed fields. We conclude that when determining benchmark levels for the consumptive WF of a crop, it is useful to primarily distinguish between different climate zones. If actual consumptive WFs of winter wheat throughout China were reduced to the benchmark levels set by the best 25 % of Chinese winter wheat production (1224 m3 t−1 for arid areas and 841 m3 t−1 for humid areas), the water saving in an average year would be 53 % of the current water consumption at winter wheat fields in China. The majority of the yield increase and associated improvement in water productivity can be achieved in southern China.
Influence of atmospheric stratification on the integral scale and fractal dimension of turbulent flows
Authors: Tijera Manuel , Maqueda Gregorio , Yagüe Carlos 
Published: November 2016

Abstract. In this work the relation between integral scale and fractal dimension and the type of stratification in fully developed turbulence is analyzed. The integral scale corresponds to that in which energy from larger scales is incoming into a turbulent regime. One of the aims of this study is the understanding of the relation between the integral scale and the bulk Richardson number, which is one of the most widely used indicators of stability close to the ground in atmospheric studies. This parameter will allow us to verify the influence of the degree of stratification over the integral scale of the turbulent flows in the atmospheric boundary layer (ABL). The influence of the diurnal and night cycles on the relationship between the fractal dimension and integral scale is also analyzed. The fractal dimension of wind components is a turbulent flow characteristic, as has been shown in previous works, where its relation to stability was highlighted. Fractal dimension and integral scale of the horizontal (u′) and vertical (w′) velocity fluctuations have been calculated using the mean wind direction as a framework. The scales are obtained using sonic anemometer data from three elevations 5.8, 13 and 32 m above the ground measured during the SABLES 98 field campaign (Cuxart et al., 2000). In order to estimate the integral scales, a method that combines the normalized autocorrelation function and the best Gaussian fit (R2 ≥  0.70) has been developed. Finally, by comparing, at the same height, the scales of u′ and w′ velocity components, it is found that the turbulent flows are almost always anisotropic.
Percutaneous Screw Fixation of Incomplete Ossification of the Humeral Condyle in Three Dogs (Four Elbows)
Authors: Grand Jean-Guillaume Robert 
Published: November 2016

ABSTRACT
Transcondylar screw fixation was performed using a minimally invasive percutaneous technique on three dogs (four elbows) diagnosed with incomplete ossification of the humeral condyle. The technique was performed using an aiming device in all four elbow joints and assisted by intraoperative fluoroscopy in one. All screws were successfully placed on first attempt and no elbow joint required repositioning of the transcondylar screw. On immediate postoperative radiographs, median transcondylar screw angulation was 2.9° and median percentage of screw eccentricity relative to the theoretical center of the humeral condyle was 14%. No short-term postoperative complications (&lt;1 mo) were observed. The surgical technique described is a feasible option for surgical management of incomplete ossification of the humeral condyle in dogs that allowed accurate transcondylar screw placement and orientation.
Thromboembolism in Dogs with Protein-Losing Enteropathy with Non-Neoplastic Chronic Small Intestinal Disease
Authors: Jacinto Ana M. L. , Ridyard Alison E. , Aroch Itamar , Watson Penny J. , Morrison Linda R. , Chandler Marge L. , Kuzi Sharon 
Published: November 2016

ABSTRACTDogs with protein-losing enteropathy (PLE) are suggested to be at increased risk of developing thromboembolic events. However, with some exceptions, there are very few reports of thromboembolism in such dogs. This multicentre retrospective observational study describes a case series of thromboembolism (TE) in eight dogs with PLE secondary to non-neoplastic, chronic small intestinal disease. Seven dogs had poorly controlled PLE when the thromboembolic event occurred. Pulmonary thromboembolism (PTE) occurred in six dogs, while one dog developed splenic vein thrombosis and another had concurrent splenic vein and aortic TE. Six dogs died, all with PTE. Antithrombin activity was decreased in one of two dogs in which it was measured. Serum cobalamin and folate concentrations were measured in three dogs and cobalamin was subnormal in all three. Serum magnesium, measured in two dogs, was low in both. Dogs with uncontrolled chronic small intestinal disease and PLE are at risk for developing serious life-threatening TE, mostly PTE.
Use of PET/CT and Stereotactic Radiation Therapy for the Diagnosis and Treatment of Osteosarcoma Metastases
Authors: Selmic Laura Elizabeth , Griffin Lynn R. , Nolan Michael W. , Custis James , Randall Elissa , Withrow Stephen J. 
Published: November 2016

ABSTRACT
This case report describes the use of two new concepts in the diagnosis and treatment of metastatic osteosarcoma (OSA) in one dog. The dog was initially presented for positron emission tomography and computed tomography (PET/CT) as full-body staging following amputation and adjuvant chemotherapy for treatment of OSA of the proximal tibia. The initial PET/CT did not show evidence of metastatic disease. Six mo after OSA, diagnosis pulmonary metastatic nodules were identified and oral toceranib phosphate was initiated. Twelve mo postdiagnosis the dog developed neck pain and non-ambulatory tetraparesis and was diagnosed with a C7 vertebral metastatic lesion based on magnetic resonance imaging. A second PET/CT was performed to screen for further metastatic lesions, and a nodule within the right ischium was identified. The C7 and ischial lesions were treated with stereotactic radiation therapy (SRT). Sixteen mo postdiagnosis, a third PET/CT was performed due to increasing size of the pulmonary nodules and a right-sided liver metastasis was detected. The liver mass was treated with SRT. The PET/CT scans facilitated identification of gross metastatic lesions that were subsequently treated with SRT, which resulted in clinical improvement of the dog's neurological signs.
Intradural Dirofilariasis in a Dog with Chronic Cervical Pain
Authors: Bonawandt Kathleen Ann , Berg Jason M. , Joseph Richard J. , Stefanacci Joseph D. 
Published: November 2016

ABSTRACTA 7 yr old female spayed Yorkshire terrier was referred to the author's institute for a 5 mo history of recurrent cervical spinal pain. Neurologic examination did not reveal any deficits. Hematologic and serum analyses were within normal limits. Thoracic radiographs that incorporated the cervical spine did not show structural abnormalities. Magnetic resonance imaging of the cervical spine demonstrated a contrast enhancing, intradural extramedullary lesion at the level of the C2 vertebra. Hemilaminectomy was performed, during which a long, narrow nematode was visualized upon opening of the dura mater. The parasite was alive when removed during surgery, and the dog recovered with complete resolution of symptoms. The parasite was submitted and confirmed as a male adult Dirofilaria immitis. This is a novel case of an intradural D. immitis infection in the dog with a magnetic resonance imaging description of spinal D. immitis.
Collaborative Practice – wat is het en wat brengt het?
Authors: van Arkel Wampie , van Noort Irene 
Published: November 2016

Collaborative Practice – what is it and what are the benefits?
This article is about the process of Collaborative Practice, also known as Collaborative law, and more specific collaborative divorce. The aim of this article is to explain what the process entails, when it can be used, what the benefits for clients are and what a professional can gain by making this method his own.The history of the Collaborative Practice process and the manner the process was introduced from the United States to Europe are reported. Furthermore, the development of the Collaborative Practice community in Europe, with a focus on the expansion in the Netherlands and Belgium, is described.On the basis of a practical case the process will be explained and the findings, experiences and reviews from the multidisciplinary team and the clients will be exemplified.
Nanoengineered Endocytic Biomaterials for Stem Cell Therapy
Authors: Wang Yingxue , Sun Chunhui , Liu Zhaoying , Zhang Shengmin , Gao Ke , Yi Fan , Zhou Wenjuan , Liu Hong 
Published: September 2024

AbstractStem cells, ideal for the tissue repair and regeneration, possess extraordinary capabilities of multidirectional differentiation and self‐renewal. However, the limited spontaneous differentiation potential makes it challenging to harness them for tissue repair without external intervention. Although conventional approaches using biomolecules, small organic molecules, and ions have shown specific and effective functions, they face challenges such as in vivo diffusion and degradation, poor internalization, and side effects on adjacent cells. Nanoengineered biomaterials offer a solution by solidifying and nanosizing these soluble regulating molecules and ions, facilitating their uptake by stem cells. Once inside lysosomes, these nanoparticles release their contents in a controlled “molecule or ion storm,” efficiently altering the intracellular biological and chemical microenvironment to tune the differentiation of stem cells. This newly emerged approach for regulating stem cell fate has attracted much attention in recent years. This method has shown promising results and is poised to enhance clinical stem cell therapy. This review provides an overview of the design principles for nanoengineered biomaterials, discusses the categories and characteristics of nanoparticles, summarizes the application of nanoparticles in tissue repair and regeneration, and discusses the direction of nanoparticle‐enhanced stem cell therapy and prospects for its clinical application in regenerative medicine.
Mechanistic Understanding of the Underlying Energy Storage Mechanism of α‐MnO2‐based Pseudo‐Supercapacitors
Authors: Deng Lei , Wang Zaifa , Cui Hantao , Guo Yunna , Ye Zhangran , Li Hui , Zhang Xinyu , Jia Peng , Zhang Qiaobao , Zhang Liqiang 
Published: September 2024

AbstractManganese dioxide (α‐MnO2) has attracted significant research interest in supercapacitors recently. However, the reaction mechanism of α‐MnO2 in supercapacitors remains unclear. Therefore, a nano‐supercapacitor using Environmental transmission electron microscopy (ETEM) is conducted and investigated the reaction mechanism of α‐MnO2 based on three ionic liquids (ILs). It found that in the aprotic ionic liquid (AIL) 1‐ethyl‐3‐methylimidazolium trifluoromethanesulfonate (EMIMOTF), α‐MnO2 nanowires (NWs) undergo an oxidation reaction due to the presence of an active proton at the second position (H2) of the imidazole ring. As a result, α‐MnO2 NWs undergo a phase transition and transform into Mn3O4, exhibiting pseudo‐capacitive properties. Furthermore, characterization of the macroscopic α‐MnO2 electrodes after cycling reveals that after the initial charging cycles, the dominant energy storage mechanism of the supercapacitor transitions from pseudo‐capacitance to a dual‐layer capacitance formed by the combination of Mn3O4 and unreacted α‐MnO2. Simultaneously, due to the coexistence of these two energy storage mechanisms, the specific capacitance of the supercapacitor in EMIMOTF electrolyte reaches up to 80 F g−1, and the cycle number reaches as high as 1000 cycles. The results are expected to provide insights into the selection of electrolytes in supercapacitors and offer a fundamental understanding of the internal reaction mechanisms in capacitors.
Understanding the limitations of grain yield monitor technology to inform on‐farm research
Authors: Gauci Alysa , Fulton John , Shearer Scott , Barker David J. , Hawkins Elizabeth , Lindsey Alexander J. 
Published: September 2024

AbstractYield monitoring technology (YM) is a valuable tool to evaluate crop performance in on‐farm research (OFR). However, limited information exists on utilizing this technology to accurately inform OFR. The objectives of this study were to evaluate the ability of grain yield monitor mass flow sensors to detect changes in corn (Zea mays L.) yield for different plot lengths, provide a recommended minimum plot length to utilize YM in OFR, and determine if differences in estimating yield existed between YMs. Six treatment lengths that varied in distance of intentional yield differences (7.6, 15.2, 30.5, 61.0, 121.9, and 243.8 m) were created by alternating high‐yield (202 kg N/ha application) and low‐yield (0 kg N/ha application) plots. A total of four grain YMs with impact‐style mass flow sensors were used within two commercially available combines. Yield comparisons were made between the plot combine and YMs to evaluate the accuracy of each technology for detecting the magnitude of yield change across lengths using analysis of variance and exponential regression curves. Results indicated that the mass flow sensors were not sensitive enough to detect quickly changing flow rates for alternating yield changes in small plot lengths. Minimum plot lengths ranged from 43 to 107 m depending on YM. Significant differences were observed between grain YMs from different manufacturers. Future work could evaluate the influence additional crops or smaller yield differences have on the optimum OFR plot length.
Growing at the arid edge: Anatomical variations in leaves are more extensive than in stems of five Mediterranean species across contrasting moisture regimes
Authors: Alon Asaf , Ginzburg Neta , Zemach Hanita , Voet Hillary , Cohen Shabtai , David‐Schwartz Rakefet 
Published: September 2024

AbstractPremiseIncreasing aridity in the Mediterranean region affects ecosystems and plant life. Various anatomical changes in plants help them cope with dry conditions. This study focused on anatomical differences in leaves and xylem of five co‐occurring Mediterranean plant species namely Quercus calliprinos, Pistacia palaestina, Pistacia lentiscus, Rhamnus lycioides, and Phillyrea latifolia in wet and dry sites.MethodsStomatal density, stomatal length, leaf mass area, lamina composition, percentage of intercellular air spaces, and mesophyll cell area in leaves of plants in wet and dry sites were analyzed. Xylem anatomy was assessed through vessel length and area in branches.ResultsIn the dry site, three species had increased stomatal density and decreased stomatal length. Four species had increased palisade mesophyll and reduced air space volume. In contrast, phenotypic changes in the xylem were less pronounced; vessel length was unaffected by site conditions, but vessel diameter decreased in two species. Intercellular air spaces proved to be the most dynamic anatomical feature. Quercus calliprinos had the most extensive anatomical changes; Rhamnus lycioides had only minor changes. All these changes were observed in comparison to the species in the wet site.ConclusionsThis study elucidated variations in anatomical responses in leaves among co‐occurring Mediterranean plant species and identified the most dynamic traits. Understanding these adaptations provides valuable insights into the ability of plants to thrive under changing climate conditions.
Diurnal patterns of floral volatile emissions in three species of Narcissus
Authors: Losch Florian , Weigend Maximilian 
Published: September 2024

AbstractPremisePlants generate a wide array of signals such as olfactory cues to attract and manipulate the response of pollinators. The present study addresses the temporal patterns of scent emission as an additional dimension to the scent composition. The expectation is that divergent floral function is reflected in divergent qualitative and temporal emission patterns.MethodsWe used GC‐ion mobility spectrometry with an integrated pre‐concentration for automated acquisition of the temporal trends in floral volatile emissions for N. viridiflorus, N. papyraceus, and N. cantabricus subsp. foliosus.ResultsWe found a considerable increase in scent emissions and changes in scent composition for N. viridiflorus at night. This increase was particularly pronounced for aromatic substances such as benzyl acetate and p‐cresol. We found no diurnal patterns in N. papyraceus, despite a similar qualitative composition of floral volatiles. Narcissus cantabricus subsp. foliosus showed no diurnal patterns either and differed considerably in floral scent composition.ConclusionsScent composition, circadian emission patterns, and floral morphology indicate divergent, but partially overlapping pollinator communities. However, the limited pollinator data from the field only permits a tentative correlation between emission patterns and flower visitors. Narcissus papyraceus and N. cantabricus show no clear diurnal patterns and thus no adjustment to the activity patterns of their diurnal pollinators. In N. viridiflorus, timing of scent emission indicates an adaptation to nocturnal flower visitors, contradicting Macroglossum as the only reported pollinator. We propose that the legitimate pollinators of N. viridiflorus are nocturnal and are still unidentified.
Evaluating the Influence of Social Determinants of Health on Blood Phenylalanine Levels in Phenylketonuria Patients
Authors: Afseth Cassandra , Knutsen Josh , Lamborn Thomas , Vucko Erika , Havens Kirsten , Shim Soo , Baker Joshua 
Published: September 2024

ABSTRACTPhenylketonuria (PKU) is a genetic metabolic disorder that causes the accumulation of phenylalanine (Phe) in tissues, leading to intellectual disability, seizures, and socioemotional challenges. The role of social determinants of health (SDOH) in PKU management has not been formally studied, and this investigation evaluates the association between in‐home and in‐office factors on blood Phe levels in PKU patients. We conducted a retrospective chart review on over 200 patients attending the well‐resourced PKU Clinic at Lurie Children's Hospital of Chicago. Data included patients' average Phe level, various demographic information, and CDC/ATSDR social vulnerability index (SVI) score. The analysis revealed no significant association between social vulnerability status and average Phe level. However, a significant correlation was found between sapropterin dihydrochloride use and average Phe level. Age interacted separately with sex assigned at birth, pegvaliase use, total Phe samples submitted, and the presence of genetic testing to significantly influence the average Phe level. This study highlights the multifactorial influences on PKU management and underscores the importance of social resources, such as clinic social workers and state‐provided formula, in modulating the effects of SDOH on PKU control. Further research in different healthcare settings is needed to understand the social determinants affecting PKU patients comprehensively, which will strengthen advocacy efforts for this population.