bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends in self‐reported oral health of US adults: National Health and Nutrition Examination Survey 1999‐2014
Authors: Li Kar Yan , Okunseri Christopher E. , McGrath Colman , Wong May C.M. 
Published: December 2017

AbstractObjectiveSingle‐item self‐reported oral health (SROH) is a convenient and reliable measure for the assessment of population‐based oral health. However, little is known about trends and its associations among US adults. This study investigated trends in SROH (aged 20+ years) and the associated factors among adults living in the United States.MethodsSelf‐reported oral health data for 41 621 adults aged 20+ years from the National Health and Nutrition Examination Survey (NHANES) 1999 to 2014 were analysed. Survey‐weighted descriptive statistics were computed to provide nationally representative estimates. Multivariable logistic regression was performed separately for each survey period with SROH as the primary outcome. Independent variables included were age, gender, race/ethnicity, education level and family poverty income ratio or PIR. Pooled survey‐weighted multivariable logistic regression was also performed to consider possible time‐changing effects.ResultsThe survey‐weighted proportions of “excellent or very good” in SROH increased from 27% in 1999‐2000 (n = 4873) to 38% in 2013‐2014 (n = 5765). Separate multivariable logistic analyses for each survey period suggested that females, Whites (vs Mexican and Black Americans) as well as respondents from high family PIR had higher odds of reporting their oral health as “excellent or very good” (P < .05). The pooled multivariable logistic model confirmed results in the separate logistic regression, and respondents in the more recent survey periods had higher probabilities of reporting “excellent or very good” oral health. Respondents aged 50‐59 years were found to have relatively lower probabilities of reporting “excellent or very good” oral health, while people aged 20‐29 years had higher probabilities than those aged 30‐39 years. Compared to respondents with lower education, those with higher education were more likely to report their oral health as excellent or very good.ConclusionsSelf‐reported oral health improved from 1999 to 2014. In general, respondents who were young, female, White, had higher education or higher income or were surveyed in more recent years reported excellent or very good oral health.
Comparative sorption isotherms for colorants present in Dyers’ madder (Rubia tinctorum L.) provide new insights into historical dyeing
Authors: Ford Lauren , Rayner Christopher M. , Blackburn Richard S. 
Published: December 2017

Dyers madder (Rubia tinctorum L.) has been famously used throughout history as a source of red dye. The sorption onto mordanted wool of the major colorant components of R. tinctorum, alizarin and the glycosides ruberythric acid and lucidin primeveroside, is studied herein. Sorption of a purified 1:1 mixture of ruberythric acid:lucidin primeveroside most closely followed a Temkin isotherm (R2 0.925), whereas alizarin followed a Freundlich isotherm (R2 0.940). These results were compared with HPLC chromatograms of English, Turkish and Iranian varieties of R. tinctorum before and after dyeing, where it was observed that the glycosides are shown to have the highest uptake onto wool. The higher sorption energy of the purified 1:1 ruberythric acid:lucidin primeveroside mixture (–11.4 kJ mol−1) compared with alizarin (–5.8 kJ mol−1) is in agreement with the HPLC results, indicating that the ruberythric acid/lucidin primeveroside mixture has a substantially higher affinity for wool compared with alizarin. Not only do the glycosides show higher affinity for the wool, but greater interactions between adsorbed species suggest a more extensive aggregation of dye on the surface of the wool. These observations are in contrast with much of the literature and bring into question previous conclusions that alizarin was the main dyeing species throughout history.
Falls in older adults with multiple myeloma
Authors: Wildes Tanya M. , Fiala Mark A. 
Published: December 2017

AbstractObjectiveTo examine the prevalence of falls, factors associated with falls and the relationship between falls and survival in older adults with multiple myeloma.MethodsIn an analysis of the Surveillance, Epidemiology and End Results (SEER)‐Medicare Health Outcomes Survey (MHOS)‐linked database, we examined 405 older adults with multiple myeloma (MM) and 513 matched non‐cancer controls. The primary outcome was self‐reported within the past 12 months. Age, race, gender, symptoms, and comorbidities were self‐reported in the MHOS. Survival was calculated from SEER data.ResultsOf the patients with MM, 171 were within 1 year of diagnosis (cohort 1) and 234 were ≥1 year postdiagnosis (cohort 2). Patients in cohorts 1 and 2 were more likely to have fallen than controls (26% and 33% vs 23%, P = .012). On multivariate analysis, among patients with myeloma (combined cohorts 1 and 2), factors associated with falls included self‐report of fatigue (aOR 2.52 [95% CI 1.34‐4.93]), depression (aOR 1.90 [95% CI 1.14‐3.18]), or poorer general health (aOR 1.86 [95% CI 1.05‐3.36]). Falls were not associated with survival.ConclusionsOlder adults with MM have a greater prevalence of falls than matched controls. Self‐reported fatigue, depression, and poorer general health are associated with greater odds of falls.
A prediction method for fatigue life of large moving components as function of scale factor: A case of motor‐generator rotor
Authors: Pan L. , Pang J.C. , Zhang M.X. , Xie Y.J. , Nie L.L. , Mao Y.X. , Chen M. , Zhang Z.F. 
Published: December 2017

AbstractWith the development of science and technology, more and more large moving components have been used in industry, and their service lives have become an important issue. After analysis of the previous results, considering the scale factor, a prediction method for fatigue life of large moving components based on the Basquin relation was proposed at first, and then the magnet pole part of motor‐generator rotor was chosen to make simulation parts with different scale factors mainly in terms of their S‐N curves and fractographies. It was found that with the change of specimen scale factor, the stress concentration factor at transition arc is almost unchanged as well as the fatigue strength exponent, and the fatigue strength coefficient changes linearly. Based on those results, a life prediction method was validated, and the results show that this method is a simple but more precise relation. After fatigue fracture surface and crack growth angle observations and quantitative analyses, the fatigue damage mechanisms associated with the relation among fatigue strength exponent and coefficient and scale factors were explained well. Those studies will provide a new clue to the prediction of the service life for those large moving components.
Shaping a buyer's software selection process through tendering legislation
Authors: Boonstra Albert , van Offenbeek Marjolein A.G. 
Published: December 2017

AbstractTendering legislation aims to enhance competitiveness by promoting equality, proportionality, transparency, and non‐discrimination. Such legislation applies to the procurement of software packages by public institutions in many countries. This study explores how tendering legislation shapes a buyer's software selection process through the lens of competing decision‐making rationalities. From the literature, 3 rationalities enacted in software selection are deduced that we relate to the software selection literature regarding tendering legislation. Through this lens, we subsequently examine how a large health care provider selected a supplier for an electronic health record system after an extensive tendering process. Many health care professionals within this organization were in favour of a particular software package. Yet, the organization purchased a different package from a relatively unknown supplier, the implementation of which failed. The actors involved experienced shaping on 5 decision‐making themes, the implications of which are evaluated against the functional, economic, and political rationality norms derived from the literature. The findings suggest that compliance with tendering legislation over the public procurement of software results in increased legal complexity, greater linearity and objectivity, more extensive formalization, and less relational communication. Functional norms of rationality are stressed, seemingly to balance the enforced economic norms of rationality and to compensate for the decreased room for political rationality. Even so, the shaping by the tendering legislation threatens functional rationality. Ultimately functional and economic norms of rationality win over political rationality, yet the latter still dribbles through, albeit in a different guise than reported for software selection in general.
Macroecological patterns of sexual size dimorphism in turtles of the world
Authors: Agha M. , Ennen J. R. , Nowakowski A. J. , Lovich J. E. , Sweat S. C. , Todd B. D. 
Published: December 2017

AbstractSexual size dimorphism (SSD) is a well‐documented phenomenon in both plants and animals; however, the ecological and evolutionary mechanisms that drive and maintain SSD patterns across geographic space at regional and global scales are understudied, especially for reptiles. Our goal was to examine geographic variation of turtle SSD and to explore ecological and environmental correlates using phylogenetic comparative methods. We use published body size data on 135 species from nine turtle families to examine how geographic patterns and the evolution of SSD are influenced by habitat specialization, climate (annual mean temperature and annual precipitation) and climate variability, latitude, or a combination of these predictor variables. We found that geographic variation, magnitude and direction of turtle SSD are best explained by habitat association, annual temperature variance and annual precipitation. Use of semi‐aquatic and terrestrial habitats was associated with male‐biased SSD, whereas use of aquatic habitat was associated with female‐biased SSD. Our results also suggest that greater temperature variability is associated with female‐biased SSD. In contrast, wetter climates are associated with male‐biased SSD compared with arid climates that are associated with female‐biased SSD. We also show support for a global latitudinal trend in SSD, with females being larger than males towards the poles, especially in the families Emydidae and Geoemydidae. Estimates of phylogenetic signal for both SSD and habitat type indicate that closely related species occupy similar habitats and exhibit similar direction and magnitude of SSD. These global patterns of SSD may arise from sex‐specific reproductive behaviour, fecundity and sex‐specific responses to environmental factors that differ among habitats and vary systematically across latitude. Thus, this study adds to our current understanding that while SSD can vary dramatically across and within turtle species under phylogenetic constraints, it may be driven, maintained and exaggerated by habitat type, climate and geographic location.
Investigating canine elbow joint stabilisation through mechanical constraints of the deep fascia and other soft tissues
Authors: Chong Timothy E. , Davies Helen M. S. 
Published: December 2017

AbstractThe objective of this research was to investigate how the range of flexion and extension of the canine elbow joint is constrained by the mechanical connections and attachments of soft tissue structures. The skin, a section of deep fascia and several muscles from both forelimbs from six adult greyhounds and seven other breeds were sequentially transected or removed, over 13 steps. During each step, repeated measurements of elbow flexion and extension were recorded using a goniometer. Only marginally significant changes to the range of flexion occurred in any of the 13 steps or overall for the greyhounds. Clearly significant changes to extension occurred in several dissection steps. Removing the skin resulted in a significant increase in elbow extension of 1.7° ± 0.3 (P < 0.001) in the greyhounds and 1.6° ± 0.3 (P < 0.001) in the other breeds. Severing the deep fascia from the humerus and its connections across the elbow joint resulted in the largest significant change in elbow extension of 9.9° ± 0.3 (P < 0.001) in the greyhounds and 6.9° ± 0.7 (P < 0.001) in the other breeds. Transecting the biceps brachii m. close to the elbow resulted in an increase of 2.8° ± 0.3 (P < 0.001) in the greyhounds but a non‐significant change in the other breeds. Transecting the extensor carpi radialis m. from its origin resulted in an increase of 5.5° ± 0.4 (P < 0.001) in the greyhounds and 3.9° ± 0.7 (P < 0.001) in the other breeds. These results suggest that the collagenous framework and attachments of the skin, deep fascia, and extensor carpi radialis m., play a significant role in the function of the canine elbow by restricting it from overextension and hence stabilising it during periods of loading, in a variety of different canine breeds, and that these structures are functionally integrated into the way the forelimb supports the bodyweight separately from any involvement of muscle tone or muscle movements. Observations on the anatomical connections of the deep fascia between the cranial distal humerus and the antebrachial fascia highlighted its probable importance in relating movements between the shoulder and the carpus.
Development of a picture‐scale‐questionnaire to assess liking for fatty, salty, sweet, and umami seasonings compared to a sensory evaluation for Japanese consumers
Authors: Nakano Yuko , Wakita Andrea , Kasamatsu Chinatsu , Nonaka Masahiko , Kasai Midori , Schlich Pascal 
Published: December 2017

AbstractPrefQuest is a web‐based questionnaire that measures the liking for sweet, fatty‐sweet, salty, and fatty‐salty sensations using combinations of images of French food items. We adapted the original PrefQuest questionnaire for Japanese respondents (J‐PrefQuest). J‐PrefQuest comprises 17 Japanese food items categorized into four sensations: fatty, salty, sweet, and umami. Participants responded by indicating their preferred level of seasoning for each food item on a 6‐point scale. Segmentation of 161 respondents identified groups who preferred: (a) high amount of umami seasonings; (b) low amount of umami seasonings; (c) high amount of fatty and low amount of salty seasonings. To validate the questionnaire, 70 female university students were recruited for a sensory evaluation of five levels of seasoning used for six food items on a 9‐point hedonic scale before completing the questionnaire. The validity of J‐PrefQuest questionnaire was then analyzed by comparing the two results.Practical applicationsMeasuring personal preference or “liking” for the taste of food items is important as such information may contribute to the prevention of various diseases and improve the quality of life of consumers. We developed a simple questionnaire with pictures to evaluate the liking for fatty, salty, sweet, and umami sensations of Japanese respondents. This questionnaire focuses on typical seasonings added to different Japanese food items and provides objective information about liking different food sensations. Thus, it has application as an important screening tool to identify respondents who may need to make their food consumption behavior more healthy. Moreover, following minor modifications, this questionnaire could also be used in other Asian countries where plain white rice is the stable food.
Serological responses to revaccination with hepatitis A virus (HAV) vaccines among HIV‐positive individuals whose anti‐HAV antibody waned after primary vaccination
Authors: Chen Guan‐Jhou , Sun Hsin‐Yun , Lin Kuan‐Yin , Cheng Aristine , Huang Yi‐Chia , Hsieh Szu‐Min , Sheng Wang‐Huei , Liu Wen‐Chun , Hung Chien‐Ching , Chang Shan‐Chwen 
Published: December 2017

AbstractBackgroundAmong HIV‐positive individuals, seroprotection for hepatitis A virus (HAV) following primary vaccination may wane with time. However, seroresponses to HAV revaccination are rarely investigated among HIV‐positive patients who have lost protective antibodies after primary vaccination.MethodsDuring the outbreak of acute hepatitis A in Taiwan after June 2015, HAV‐seronegative, HIV‐positive individuals were advised to receive two doses of HAV vaccines at 24 weeks apart. A retrospective 1:2 matched case‐control study was conducted to compare the seroresponses at weeks 4, 24, 28 and 48 of HAV vaccination between those who underwent revaccination after having lost protective antibodies (case patients) and those who underwent primary vaccination (controls).ResultsSeventy‐five case patients and 150 matched controls were included. The serological response rates were consistently higher among the case patients than controls: 88.1% vs 10.5% at week 4 following the first dose of HAV vaccination (P < .001); 93.3% vs 46.0% at week 24 (immediately before the second dose; P < .001); 98.7% vs 62.7% at week 28 (4 weeks after the second dose; P < .001) and 98.7% vs 92.7% at week 48 (P = .06). The anti‐HAV antibody titres as reflected by the semi‐quantitative assay for the case patients were also significantly higher than the controls at weeks 24, 28 and 48 following HAV vaccination.ConclusionsWe demonstrated faster and better serological responses to HAV revaccination among the HIV‐positive individuals who had lost their anti‐HAV antibodies after primary vaccination. Single dose of HAV revaccination may provide rapid and sufficient seroresponses for HAV during the outbreak of acute hepatitis A.
Amino acid deprivation and central carbon metabolism regulate the production of outer membrane vesicles and tubes by Francisella
Authors: Sampath Vinaya , McCaig William D. , Thanassi David G. 
Published: December 2017

SummaryFrancisella tularensis is a highly virulent Gram‐negative bacterial pathogen that causes the zoonotic disease tularemia. F. novicida, a model tularemia strain, produces spherical outer membrane vesicles (OMV), as well as novel tubular vesicles and extensions of the cell surface. These OMV and tubes (OMV/T) are produced in a regulated manner and contain known virulence factors. Mechanisms by which bacterial vesicles are produced and regulated are not well understood. We performed a genetic screen in F. novicida to decipher the molecular basis for regulated OMV/T formation, and identified both hypo‐ and hyper‐vesiculating mutants. Mutations in fumA and tktA, involved in central carbon metabolism, and in FTN_0908 and FTN_1037, of unknown function, resulted in severe defects in OMV/T production. Cysteine deprivation was identified as the signal that triggers OMV/T formation in F. novicida during growth in rich medium. We also found that fully virulent F. tularensis produces OMV/T in a similarly regulated manner. Further analysis revealed that OMV/T production is responsive to deprivation of essential amino acids in addition to cysteine, and that the hypo‐vesiculating mutants are defective in responding to this signal. Thus, amino acid starvation, such as encountered by Francisella during host cell invasion, regulates the production of membrane‐derived structures.
Peptidoglycan hydrolysis mediated by the amidase AmiC and its LytM activator NlpD is critical for cell separation and virulence in the phytopathogen Xanthomonas campestris
Authors: Yang Li‐Chao , Gan Yong‐Liang , Yang Li‐Yan , Jiang Bo‐Le , Tang Ji‐Liang 
Published: December 2017

SummaryThe essential stages of bacterial cell separation are described as the synthesis and hydrolysis of septal peptidoglycan (PG). The amidase, AmiC, which cleaves the peptide side‐chains linked to the glycan strands, contributes critically to this process and has been studied extensively in model strains of Escherichia coli. However, insights into the contribution of this protein to other processes in the bacterial cell have been limited. Xanthomonas campestris pv. campestris (Xcc) is a phytopathogen that causes black rot disease in many economically important plants. We investigated how AmiC and LytM family regulators, NlpD and EnvC, contribute to virulence and cell separation in this organism. Biochemical analyses of purified AmiC demonstrated that it could hydrolyse PG and its activity could be potentiated by the presence of the regulator NlpD. We also established that deletion of the genes encoding amiC1 or nlpD led to a reduction in virulence as well as effects on colony‐forming units and cell morphology. Moreover, further genetic and biochemical evidence showed that AmiC1 and NlpD affect the secretion of type III effector XC3176 and hypersensitive response (HR) induction in planta. These findings indicate that, in addition to their well‐studied role(s) in cell separation, AmiC and NlpD make an important contribution to the type III secretion (T3S) and virulence regulation in this important plant pathogen.
Autonomy‐supportive, Web‐based lifestyle modification for cardiometabolic risk in postmenopausal women: Randomized trial
Authors: Kim Hye‐Ryoung , Kim Hee‐Seung 
Published: December 2017

AbstractThe management of cardiometabolic risk factors, such as abdominal obesity, dyslipidemia, hypertension, and hyperglycemia, is essential for the health of postmenopausal women. In this study, we identified the effects of autonomy‐supportive, Web‐based lifestyle modification for the management cardiometabolic risk of postmenopausal women, and assessed the mediation effect of intrinsic motivation. This study was a randomized trial involving 71 postmenopausal Korean women. For the intervention group, we provided the Web‐based autonomy supports for 12 weeks; however, for the control group, individual consultations on healthy lifestyle was conducted at the first meeting. In the intervention group, cardiometabolic risks ameliorated as follows: waist circumference and waist‐to‐height ratio decreased by 3.9 cm and 0.03 cm, respectively; triglycerides decreased by 8.5 mg/dl; triglycerides‐to‐high‐density‐lipoprotein cholesterol ratio decreased by 0.21; systolic blood pressure decreased by 3.3 mmHg, and the visceral adiposity index decreased. Among the subdomain of intrinsic motivation, perceived competence, effort/importance, and perceived choice showed an association with waist circumference changes. Web‐based autonomy supports can be effective in implementation and maintenance, and the amelioration of cardiometabolic risk in postmenopausal women.