bluuebunny/crossref_metadata_2025_split huggingface dataset:
The microtubule-severing protein fidgetin acts after dendrite injury to promote their degeneration
Authors: Tao Juan , Feng Chengye , Rolls Melissa M. 
Published: July 2016

ABSTRACT
After being severed from the cell body, axons initiate an active degeneration program known as Wallerian degeneration. Although dendrites also seem to have an active injury-induced degeneration program, no endogenous regulators of this process are known. Because microtubule disassembly has been proposed to play a role in both pruning and injury-induced degeneration, we used a Drosophila model to identify microtubule regulators involved in dendrite degeneration. We found that, when levels of fidgetin were reduced using mutant or RNA interference (RNAi) strategies, dendrite degeneration was delayed, but axon degeneration and dendrite pruning proceeded with normal timing. We explored two possible ways in which fidgetin could promote dendrite degeneration: (1) by acting constitutively to moderate microtubule stability in dendrites, or (2) by acting specifically after injury to disassemble microtubules. When comparing microtubule dynamics and stability in uninjured neurons with and without fidgetin, we could not find evidence that fidgetin regulated microtubule stability constitutively. However, we identified a fidgetin-dependent increase in microtubule dynamics in severed dendrites. We conclude that fidgetin acts after injury to promote disassembly of microtubules in dendrites severed from the cell body.
Investigating Purchase Conversion by Uncovering Online Visit Patterns
Authors: Park Chang Hee , Park Young-Hoon 
Published: July 2016

This research aims to understand and predict online customers’ store visit and purchase behaviors. To this end, we develop a model that accounts for different patterns of online store visits at the individual level. Given the latency of visit patterns, we employ a changepoint modeling framework and statistically infer them using a Bayesian approach. The inferences obtained are then used to examine the effects of visit patterns on purchase dynamics across store visits. Using Internet clickstream data at an online retailer, we find that online store visit patterns tend to be clustered with significant variation across customers in terms of the number and size of visit clusters as well as the visit frequencies, both within and between clusters. Furthermore, the conversion rates vary significantly, depending on store visit patterns, such that they tend to be higher at later visits within a visit cluster, compared with earlier visits. The proposed model thereby offers superior fit and predictive performance than benchmark models that ignore clustered visit patterns and their impact on purchase behavior. We demonstrate the model’s ability to better identify prospective customers by utilizing their visit patterns, which can assist marketers in scoring customers and making targeting decisions across individuals for marketing activity.Data, as supplemental material, are available at https://doi.org/10.1287/mksc.2016.0990 .
Do Stock Options Overcome Managerial Risk Aversion? Evidence from Exercises of Executive Stock Options
Authors: Heron Randall A. , Lie Erik 
Published: July 2016

We report that the probability that executives exercise options early decreases with the volatility of the underlying stock return. We interpret this to mean that executives’ subjective option value increases with volatility and that option grants increase executives’ risk appetite. Further decomposition reveals that the results are most pronounced for idiosyncratic volatility, consistent with our conjecture that executives believe they can better predict or influence the resolution of idiosyncratic uncertainty than systematic uncertainty and, thus, favor the former. Data are available at http://dx.doi.org/10.1287/mnsc.2016.2495 . This paper was accepted by Wei Jiang, finance.
A single-centre, retrospective study of cryopreserved umbilical cord/amniotic membrane tissue for the treatment of diabetic foot ulcers
Authors: Raphael A. 
Published: July 2016

Objective: Histopathological studies have shown a prolonged inflammatory phase in wounds of patients with diabetes, delaying formation of mature granulation tissue and reducing wound tensile strength, making these wounds difficult for physicians to heal. Cryopreserved human umbilical cord (cUC) tissues possess unique anti-inflammatory and anti-scarring properties and have been found to help improve closure of these chronic wounds. Method: A retrospective chart review was performed to assess the efficacy of cUC as an advanced treatment modality to help promote the closure of chronic DFUs. Overall healing rate, duration to wound closure, and number of cUC applications used to achieve closure were used to assess cUC treatment efficacy. Results: A total of 32 wounds in 29 patients treated at a single health-care centre were included in the study population The average initial wound area for all wounds was 10.6 ± 2.15cm2. Of the 32 wounds 28 achieved complete epithelialisation for an overall healing rate of 87.5%. Average time to wound closure was 13.8 ± 1.95 weeks with a median of 9 weeks and an average of 1.68 ± 0.18 cUC applications. Conclusion: The results suggest cUC allograft may be effective in improving the healing of DFUs ulcers as well as potentially reducing the medical costs associated with chronic DFUs due to the low number of applications needed to achieve complete wound closure. Prospective, randomised controlled trials are suggested to better understand the efficacy of cUC in chronic wound healing. Declaration of interest: Dr Raphael is a paid speaker for Amniox Medical, Inc.
Ottonostalgias and Urban Apartheid
Authors: De Cesari Chiara 
Published: July 2016

Abstract
A widespread nostalgia for the Ottoman period is visible in numerous urban regeneration projects proliferating across the Middle East. This article explores how Ottoman heritage in Palestine and Istanbul both propels oppressive sociospatial schemes and forms the basis for social movements formed to contest these schemes. In Istanbul, the banner of urban regeneration has been used to expropriate and displace local populations in a context marked by rapidly escalating real estate values and huge profits realized by developers allied with an entrepreneurial political class. The politically-driven heritagization occurring in Istanbul uncannily resembles the efforts aggressively pushed forward by an alliance between Israeli settlers and the government in Israel/Palestine – a form of class cleansing as opposed to a predominantly ethnic one targeting Palestinians. In response, Palestinian heritage organizations are endeavouring to rehabilitate old cities in towns and villages of the West Bank, in an attempt to improve the economic and social livelihoods of Palestinians and help them resist colonization.
Responses to the Destruction of Syrian Cultural Heritage: A Critical Review of Current Efforts
Authors: Al Quntar Salam , Daniels Brian I. 
Published: July 2016

Abstract
The Syrian civil war has resulted in over 250,000 deaths and several million displaced refugees within Syria and abroad. In addition to this human toll, the conflict has resulted in the devastation of the country’s acclaimed cultural heritage sites and the historical fabric that composed the country’s social landscape and the identity of its population. In this article, we consider the reaction of the international heritage community to this moment of crisis. To date, the international heritage community has developed three kinds of projects: site documentation projects; public-awareness-raising projects; and emergency training and mitigation projects. Most of these undertakings have prioritized the collection and dissemination of information about heritage loss. Less attention has been given to emergency interventions to support Syrians inside the country and the at-risk heritage. A significant gap exists between international knowledge about heritage in this crisis and the immediate needs of Syrian heritage professionals. Here, we consider some of the reasons for the divergence between on-the-ground-need and international response, along with the intended and unintended outcomes resulting from the documentation and public-awareness-raising projects. In terms of tangible results, there is no substitute for efforts conducted within a humanitarian framework. The challenge is in encouraging the international heritage community to embrace such an approach.
Précis
Authors: Roberson Jennifer , Michelsen Leslee 
Published: July 2016

Abstract
NORTHERN CALIFORNIA ART HISTORIANS ‘OLD SPACES, NEW NARRATIVES: ISLAMIC ARCHITECTURE IN THE 20TH AND 21ST CENTURIES’, COLLEGE ART ASSOCIATION 103RD ANNUAL CONFERENCE, NEW YORK, FEBRUARY 11–14, 2015
BAMIYAN CULTURAL CENTRE DESIGN COMPETITION ANNOUNCEMENT, UNESCO OFFICE, KABUL, AFGHANISTAN, FEBRUARY 18, 2015
Inequalities for casorati curvatures of submanifolds in real space forms
Authors: Zhang Pan , Zhang Liang 
Published: July 2016

Abstract
Using Oprea’s optimization methods on submanifolds, we give another proof of the inequalities relating the normalized δ-Casoraticurvature

δ
^

$\hat \delta $

c(n−1) for submanifolds in real space forms. Also, inequalities relating the normalized δ-Casorati curvature δC(n − 1) for submanifolds in real space forms are obtained. Besides, we characterize a kind of Casorati ideal hypersurface of Euclidean 4-space. We also show that this kind of Casorati ideal hypersurface is rigid.
Migration measurement of the cemented Lubinus SP II hip stem – a 10-year follow-up using radiostereometric analysis
Authors: Sesselmann Stefan , Hong Yutong , Schlemmer Frank , Wiendieck Kurt , Söder Stephan , Hussnaetter Isabell , Müller Lutz Arne , Forst Raimund , Wierer Thomas 
Published: July 2016

Abstract
In a previous radiostereometric analysis (RSA) of the Lubinus SP II (Link, Hamburg, Germany), which is one of the most often used cemented hip stems worldwide, our research group detected a very small but statistically significant distal migration of -0.03±0.17 mm 2 years after surgery compared to the postoperative radiograph. Maximum subsidence occurred between 6 and 12 months. The implant appeared to have stabilized after 2 years. The mean value of maximum total point motion (MTPM) was 0.99±0.69 mm, which was detected 2 years after surgery. The purpose of this study was to analyze the migration pattern and to verify the predictive value of short-term RSA of the Lubinus SP II stem after 10 years. After a follow-up of 5 and 10 years, 38 and 27 out of 100 patients remained available for further assessment, respectively. No statistically significant implant translation or rotation was found along or about the axes of the global coordinate system 5 and 10 years after surgery with respect to the postoperative radiograph. Furthermore, the MTPM was stable in both follow-up periods. The results suggest that the Lubinus SP II hip stem is still stable 10 years after surgery, supporting that determining prognosis by short-term RSA follow-up of 2 years could be an appropriate tool for appraisal of implant behavior 10 years after surgery.
Territorial Self-Governing Units of the Czech Republic as Entities Possessing Ownership and Other Proprietary Rights (the Basic Conceptual Issues)
Authors: Havlan Petr , Janeček Jan 
Published: July 2016

Abstract
The property owned by self-governing units represents an important socioeconomic factor with the potential to affect a wide range of aspects of life, considering the scope of self-governing units.
The aim of this paper is to present an overview of the recent legal regulations regarding the proprietary position of Czech self-governing units (municipalities and regions) as well as comments on their development (considering wider circumstances) from 1990 to the present day. It focuses on the nature of legal entities sui generis (in Czech called “příspěvková organizace”), which perform ownership and other proprietary rights of the municipalities and regions on the basis of specific public law relations. Appropriate attention is also dedicated to other legal subjects operating in the sphere of territorial self-government considering their proprietary position. The sub-objectives of the article are the identification and explanation of solutions to the identified problems concerning the analyzed questions.
The methodological part of the article is based on the analysis and critical evaluation of the current state of the discussed legal issues. The authors use the methods of legal hermeneutics to obtain correct interpretations of the analyzed legal regulations.
The entities sui generis in question are found to be a relic of the transition period in Czech legal development after the 1990s and should be replaced with up-to-date forms of a public legal entity.
Evaluation of the possibility of the sewage sludge gasification gas use as a fuel
Authors: Werle Sebastian , Dudziak Mariusz 
Published: July 2016

Abstract
Biomass is one of the major sources of energy that is estimated to contribute between 10% and 14% of the world’s energy supply. Over the past several years, many societies have established policy targets to increase their production of renewable energy from biomass. The thermo-chemical utilization of biomass includes 4 technologies: the most popular combustion and co-firing, and unconventional: pyrolysis and gasification. Gasification is considered to be the perspective technology because has many advantages in comparison to traditional process of combustion: (1) limited emission of the SO2, NOx, oxides of the heavy metals and no risk of the dioxins and furans emission due to reducing atmosphere in the gasification reactor, (2) volume of the gasification gas is smaller in comparison to flue gases from combustion due to the reducing atmosphere, (3) gasification process produce gas which is potential gaseous fuel in power engineering (engines, gas turbines and boilers) and chemistry. Unfortunately, composition of the gasification gas is always described as a variable. Moreover, it depends on the conditions of the process and quality of the base fuel. For this reason, the use of gasification gas can’t be very easy. For this reason, the knowledge of the basic properties of the gas is very important. Laminar burning velocity is assumed as an important quantity for in the process of the design equipment for the gas utilization. The numerical and experimental results of the laminar burning velocity of sewage sludge gasification gases were presented. Experimental Bunsen burner method was used. Cosilab 3© software for numerical analysis was used. GRI-Mech 3.0 mechanism of gas oxidation was implemented. As a result of the work, the set of the parameters where the sewage sludge gasification gas combustion process is stable with effective heat release, were presented.
Statistical analysis of the associations between phenolic monoterpenes and molecular markers, AFLPs and SAMPLs in the spice plant Oregano
Authors: Azizi Ali , Ardalani Hamidreza , Honermeier Bernd 
Published: July 2016

Summary

Introduction: Molecular markers are the examples of the contribution of genome technology to medicinal plant breeding through marker-assisted selection (MAS) for pharmaceutical quality.

Objective: Forty-two accessions of Origanum vulgare L. originating from Europe were evaluated to detect genomic and chemotypic polymorphisms and to discover possible associations between them.

Methods: A total of 477 molecular polymorphisms including 214 AFLP (Amplified Fragment Length Polymorphism) and 263 SAMPL (Selectively Amplified Microsatellite Polymorphic Loci) were used for genotyping. Components in the essential oils were identified and quantified by gas chromatography (GC) and two major compounds (two economically important monoterpenes: carvacrol and thymol) were investigated.

Results: Based on results, a relatively high correlation between chemotypic patterns and genetic markers was identified. Associations between traits of interest for essential oils (carvacrol and thymol content) and genetic markers were tested using five statistical methods including three General Linear Model (GLM) and two unified Mixed Linear Model (MLM) approaches. Significant associations were found for 3 AFLP and 20 SAMPL with three key traits including essential oil yield, carvacrol and thymol content.

Conclusion: These associations can constitute a useful starting point for marker-assisted selection. Therefore, the results provide the basis for molecular breeding of O. vulgare for pharmaceutical purposes.
An update on the occurrence of resistance-breaking populations of root-knot nematodes (Meloidogyne spp.) on resistant tomato in Greece with six new records from Crete
Authors: Tzortzakakis E.A. , Vieira dos Santos M.-C. , Conceição I. 
Published: July 2016

Summary
The available published information on the occurrence of resistance-breaking populations of root-knot nematodes (Meloidogyne spp.) on resistant tomato in Greece is updated. Within the period 1994-2013, 13 populations (11 M. javanica and 2 M. incognita) able to reproduce on resistant tomato had been recorded in the regions of Crete, Epirus, Thrace, Peloponissos and Macedonia. In the present study six more resistance-breaking populations, four M. javanica and two M. incognita, were detected in the period 2013-2014, all originating from greenhouse vegetables in Crete. Four of these populations, two M. javanica and two M. incognita, originated from the region of Ierapetra. This is the first time that such populations are found in this major area of greenhouse vegetable production of Crete.
Insecticidal effect of Fusarium subglutinans on Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae)
Authors: Demirözer O. , Uzun A. , Arici Ş.-E. , Gep İ. , Bakay R. 
Published: July 2016

Summary

Fusarium subglutinans (Ascomycota: Nectriaceae) is known to have lethal effects on aphid species, while there are limited studies associated with other arthropods. In this study, the effect of different spore concentrations (1×104, 1×106 and 1×108 spores/ml) of F. subglutinans 12A, isolated from Aphis gossypii in Adana-Karataş (Turkey), was investigated on Frankliniella occidentalis (Pergande) (Thysanoptera: Thripidae) females and on 2nd instar nymphs (only 1×106 spores/ml). The application method was by dipping and observations on mortality of females were conducted 24, 48, 72, 96 hours and 7 and 9 days after application. Mycosis was also observed on dead individulas. Mortality of nymphs was recorded during 8 days after application. Higher average dead females were found in the treatments compared to the control, but there was not significant difference between the tested concentrations (Mycosis rate recorded in 1×106 spores/ml was higher than those in 1×104 and 1×108 spores/ml). The highest and lowest mycosis rates were observed on the 7th and 3rd day, respectively. Average number of dead 2nd instar nymphs recorded in 1×106 spores/ml did not differ from control.
The Transfiguration of the Real in Abstract Painting
Authors: Wunenburger Jean-Jacques 
Published: July 2016

Abstract
This article challenges a series of assumptions associated with abstract painting, arguing that this type of art makes one understand a visual manifestation which does no longer refer to the visible world only, but also to an intelligible world, accessible to the senses. Non-figurative painting abandons the reproduction of the visible, in order to present us with the invisible, and in order to account for this phenomenon the author elaborates three types of philosophical decision to interpret the mode of being of the image. The comprehension of this original experience of abstract art is then compared to the relations between the visible and the invisible, as Christian theology delineates them. Christianity is defined first by the experience of the figuration of God, by His embodiment, which actually enables one to conceive of certain images, such as the icon of the Orthodox liturgy, but at the same time it also bestows, for the first time, an incredible status to the disappearance of the visible divine body, when it returns to the invisible, while remaining present in the visible.
The Measure of the Soul
Authors: Lovișteanul Emilian Nica 
Published: July 2016

Abstract
Starting from the assumption that everything is measured in this world, the author sets out to ask some questions about the value and the measure of the human soul and postulates that we should distinguish between an earthly measure and a divine measure of the soul. He concludes that the “positive” measure of the soul is acquired according to its redemption and salvation for the eternal life, because a saved soul is worthier than the whole world (acc. Luke 9,25).
Radiofrequency Catheter Ablation of Parahisian Accessory Pathway
Authors: Korodi Szilamér , Kovács István , Benedek Edvin , Mester András , Jani Laura , Stănescu Alexandra , Benedek Imre 
Published: July 2016

Abstract
Radiofrequency catheter ablation of parahisian accessory pathways in pre-excitation syndrome is a challenging task, due to the extremely high risk of complete atrioventricular block. In this brief report we describe the case of a 32 year-old man presenting a parahisian accessory pathway, who has been successfully treated by radiofrequency ablation. Radiofrequency catheter ablation using low-power radiofrequency current is considered to be the most appropiate method of ablation in adult patients.
Limited Cutaneous Scleroderma-Related Pulmonary Arterial Hypertension — a Case Report
Authors: Ţilea Ioan , Bocicor Elena Andreea , Gal Codruţa Maria , Varga Andreea 
Published: July 2016

Abstract

Background: Pulmonary hypertension (PH), defined by mean pulmonary arterial pressure (PAPm) ≥25 mm Hg, can lead to increasing pulmonary vascular resistance, which eventually results in right ventricle failure. Scleroderma, as an autoimmune connective tissue disease, is associated with PH as a sub-group according to the 2015 ESC/ERS PH classification. Pulmonary arterial hypertension (PAH) associated with scleroderma (SSc-PAH) can often result in poor prognosis with increased mortality. Early diagnosis and specific treatment of PH can significantly improve the prognosis of these patients.

Case report: We present the case of a 50 year-old male, with no relevant family history, with a 2-year history of echocardiography-based diagnosis of PH (PAPm 78 mmHg). Physical examination revealed limited hand and forearm areas of non-folding thick skin, vital signs in the normal range and peripheral oxygen saturation of 96%. Severity and risk assessment were performed based on clinical and imaging tests, and hemodynamics. 12-lead rest ECG revealed sinus tachycardia and right bundle branch block, the six-minute walk test confirmed limited exertion capacity, Borg scale 9. Transthoracic echocardiography pointed to dilated right heart cavities and moderate pericardial effusion. Right heart catheterization confirmed the PAH (PAPm: 36 mmHg), and pulmonary CT angiography excluded massive pulmonary embolism. Rheumatologic examination and immune serology identified a scleroderma subset, limited cutaneous sclerosis form (lcSSc) with early onset PH. Combined specific PH drug therapy was initiated, followed by clinical and functional improvement in clinical status, prognosis and life quality.

Conclusions: In clinical group 1 of PH, the subgroup etiology of PAH associated with connective tissue disease (1.4.1) often goes undiagnosed, mainly due to the diminish of lung involvement symptoms in early CTD stages. Multidisciplinary approach is essential in order to refine the diagnosis and set out the treatment algorithm.