bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of Submandibular Gland Flap in the Repair of Postoperative Defects in Clinical Stage III Osteoradionecrosis of the Jaw
Authors: Liu Xiang , Shao Shengjie , Xia Yichao , Lou Huiquan , Yan Feng 
Published: September 2024

Objective:
Investigating the clinical efficacy of submandibular gland flap repair for postoperative defects in clinical stage III osteoradionecrosis of the jaw was the objective of this study.

Methods:
The study included 3 patients who declined vascularized fibula flap repair for mandibular defects and 1 patient who was not fit for mandibular reconstruction due to poor systemic condition. The postoperative defects were successfully repaired using a submandibular gland flap, and the clinical outcomes were monitored.

Results:
After a 6 to 8 month postoperative follow-up, all patients exhibited good wound healing, no signs of infection, no pain, and normal submandibular gland function.

Conclusion:
The study demonstrated that submandibular gland flap repair is an effective and feasible approach for addressing postoperative defects in clinical stage III osteoradionecrosis of the jaw, yielding satisfactory clinical results.
Impact of Gender-Affirming Surgery on Craniofacial Exposure for Plastic and Reconstructive Surgery Training: A Preliminary, Single-Institution Study
Authors: Shamamian Peter E. , Guerra Daniel , Oleru Olachi , Seyidova Nargiz , Gyasi Abena , Sarosi Alex , Horesh Elan , Taub Peter J. 
Published: September 2024

Objective:
Current available plastic surgery positions in craniofacial surgery are not commensurate with the growing number of trained plastic surgery residents and fellows interested in the field. Despite this, there is growing demand for surgery in other areas of the craniofacial field, such as facial gender-affirming surgery (GAS), in which academic plastic surgery programs can increase resident and fellow case exposure. The present study sought to characterize the increase in craniofacial surgery exposure with the introduction of a GAS rotation among plastic surgery residents at one academic medical center.

Methods:
A single-center retrospective review of ten plastic surgery resident case logs between 2013 and 2021 was carried out. Case logs were evaluated for case frequency per year in craniofacial surgery and breast reconstruction surgery, which was used as a control. Case frequency was compared before and after the introduction of the GAS rotation in 2017.

Results:
Craniofacial surgery exposure increased from an average of 26 to 45 cases per resident per year after the introduction of a GAS rotation and overall increased from 17 to 29 cases per year. The average breast reconstruction caseload remained similar at the same time, from an average of 37 to 36 cases per year per resident.

Conclusions:
The introduction of a GAS rotation at one institution increased craniofacial surgery exposure for plastic surgery residents. Increasing craniofacial surgery exposure is crucial in the competitive landscape for job opportunities, further increasing resident exposure to the transgender and gender-diverse population, and expanding care for this patient population.
Temporoparietal Fascia Sandwich Technique in the Immediate Reconstruction of Human Bite Ear Amputation
Authors: Ibrahim Ahmed , Elsayed Malek , Aboelnaga Ahmed 
Published: September 2024

Background:
Traumatic ear amputation is a rare injury. Ear replantation is the gold standard in dealing with amputated ears. However, this is not always feasible. In this case series, the authors discuss the immediate reconstruction of traumatic ear amputation using temporoparietal fascia with the same skin from the amputated ear, which provided a high esthetic result and patient satisfaction.

Patients and Methods:
The authors present a case series of 3 patients from July 2018 to May 2020 who suffered from traumatic ear amputation due to a human bite and were successfully reconstructed using temporoparietal fascia and the same skin from the amputated ear as FTSG.
The cartilage was sutured back, the temporoparietal fascia was raised and flipped over the exposed cartilage, and the FTSG previously harvested from the same amputated ear was put on the fascia. Quilting sutures were taken to ensure proper inset of the graft on the fascia. The authors measured the patient-reported outcome using an Ear-Q validated questionnaire.

Results:
All patients were males, with a mean age of 30.6 years. They were all smokers, and none of them had any comorbidities. No major complications occurred. However, partial graft loss occurred in one patient and healed properly with secondary intention. All patients had high satisfaction scores of more than 70 in the EAR-Q questionnaires.

Conclusion:
Traumatic human bite ear amputations can be reconstructed with good esthetic outcomes by using single-stage temporoparietal fascia and the same skin of the amputated ear as a full-thickness skin graft whenever replantation is not feasible.
Comparison of Clinical Outcomes Using Left and Right Liver Grafts in Adult-to-adult Living-donor Liver Transplantation: A Retrospective Cohort Study Using the Korean Organ Transplantation Registry
Authors: Jo Hye-Sung , Kim Dong-Sik , Cho Jai Young , Hwang Shin , Choi YoungRok , Kim Jong Man , Lee Jae Geun , You Young Kyoung , Choi Donglak , Ryu Je Ho , Kim Bong-Wan , Nah Yang Won , Ju Man ki , Kim Tae-Seok , Suh Suk-Won ,   Korean Organ Transplantation Registry Study Group
Published: September 2024

Background.
Living-donor liver transplantation has been widely performed as an alternative to the scarce liver grafts from deceased donors. More studies are reporting favorable outcomes of left liver graft (LLG). This study compared the clinical outcomes between living-donor liver transplantation using LLG and right liver graft (RLG) with similar graft-to-recipient body weight ratios.

Methods.
This study analyzed 4601 patients from a multicenter observational cohort using the Korean Organ Transplantation Registry between 2014 and 2021. After matching the Model for End-stage Liver Disease score and graft-to-recipient body weight ratios because of the extremely different number in each group, the LLG and RLG groups comprised 142 (25.1%) and 423 (74.9%) patients, respectively.

Results.
For donors, the median age was higher in the LLG group than in the RLG group (34 y [range, 16–62 y] versus 30 y [16–66 y] ; P = 0.002). For recipients, the LLG group showed higher 90-d mortality than the RLG group (11 [7.7%] versus 9 [2.1%]; P = 0.004). The long-term graft survival was significantly worse in the LLG group (P = 0.011). In multivariate Cox proportional hazards regression analysis for graft survival, LLG was not a significant risk factor (hazard ratio, 1.01 [0.54-1.87]; P = 0.980). Otherwise, donor age (≥40 y; 2.18 y [1.35-3.52 y]; P = 0.001) and recipients’ body mass index (<18.5 kg/m2; 2.98 kg/m2 [1.52-5.84 kg/m2]; P = 0.002) were independent risk factors for graft survival.

Conclusions.
Although the short-term and long-term graft survival was worse in the LLG group, LLG was not an independent risk factor for graft survival in multivariate analysis. LLGs are still worth considering for selected donors and recipients regarding risk factors for graft survival.
Graphene nanoplatelets on recycled rubber: an experimental study of material properties and mechanical improvements
Authors: Londono Monsalve J. M. , Kovalska E. , Craciun M. F. , Marsico M. R. 
Published: September 2024

This study presents an experimental investigation of the mechanical behaviour of recycled rubber pads coated with graphene nanoplatelets. The investigation is part of an effort to develop a novel rubber-based composite that aims to reroute rubber from end-of-life tyres from illegal landfills and incineration back into the market in the form of a novel composite for vibration isolation. Graphene nanoplatelets were deposited on rubber pads via ultrasonic spray coating. The pads were made of a combination of recycled rubber (from tyres) and virgin rubber. A comprehensive analysis of the structural and chemical properties of the graphene coating, ensuring its integrity on the rubber substrate, was performed by combining surface topography, Raman and Fourier-transform infrared (FTIR) spectroscopy. Stacked coated pads were cured and tested dynamically in compression and shear under cyclic loading. Results showed promising improvements in the mechanical properties, in particular, in compressive stiffness and damping of the coated specimens with respect to their uncoated counterparts, laying the foundation for using graphene-enhanced recycled rubber as a novel composite.
This article is part of the theme issue ‘Celebrating the 15th anniversary of the Royal Society Newton International Fellowship’.
Methylsulfonylmethane: A Potential Dietary Supplement targeting sphingosine kinase 1 involved in Glioblastomamultiforme
Authors: Ahmad Faizan , Karan Anik , Jayaraj Richard L 
Published: September 2024

AbstractMethylsulfonylmethane (MSM) is a common dietary supplement mainly used for inflammatory disorders as well as MSM had shown anti-tumor effects on different types of cancers. However, the glioma cell line has not been tested against MSM, and we are reporting it in our study for the first time. This research used an in silico study in which sphingosine kinase 1(SphK1) is used as a therapeutic target which is associated with Glioblastoma multiforme(GBM) SphK1 is pivotal enzyme for sphingolipid metabolism whose high expression level is thought to be associated with cancer alongside other inflammatory diseases and it is a potential drug target for various types of cancer.First, in silico analysis was executed to evaluate the inhibitory effect of MSM on SphK1.Then we further observed the anti-tumor activities of MSM on the C6 glioma cell line. During in silico investigation at the initial stage, we performed molecular docking with Auto Dock Vina followed by molecular dynamics simulation at 100ns with Gromacs Software Package.MSM binds with SphK1 with a docked score of -2.1 kcal mol1. During molecular dynamics simulation complex maintain stability at 10ns but we ran simulation till 100ns to confirm the stability. We performed in depth analysis which includes post trajectory analysis like free energy landscape (FEL), principal constant analysis (PCA) with kernel density (KDE)estimation plots as well as probability distribution plots. Even molecular dynamics simulation shows stability, compactness and interaction of MSM with Sphk1, we calculated MMPBSA binding energy calculation is -13.922 +/- 19.518 kJ/mol-The viability and cellular metabolic activity of the C6 glioma in the presence of MSM showed 393.459 mM/ml of MSM reduced cell viability by 50% (CTC50) value in dose dependent manner. Further analysis like DNA fragmentation assay and Acridine orange and ethidium bromide (AO/EB) staining were carried out, which clearly depicts MSM inducing apoptosis in C6 gliomas. Based on in silico and in vitro results,for the first time we are reporting it in our study and we reach to conclusion that that MSM acts as a potential inhibitor for SphK1 as well as inhibits the growth of glioma cells and acts as a potential dietary supplement for the management of GBM which can cross blood brain barrier (BBB) and not toxic to cells even at high doze.
Leveraging procurement capabilities and planning for project success in the construction industry in Ghana
Authors: Kamewor Tetteh Francis , Kwatia Dennis Amoako , Asante David , Kyeremeh Andrews , Nyame Prince Elton 
Published: September 2024

PurposeThe paper examines the influence of procurement capabilities (skills) and procurement planning on project success in Ghana. The paper further examines the mediating role of procurement planning.Design/methodology/approachDrawing insights from human capital theory, a model of four hypotheses was developed and validated. The proposed model was validated using survey data from 200 procurement and construction professionals at construction firms in Ghana. The data gathered was analysed using structural equation modelling. Confirmatory factor analysis using Amos software was conducted to establish reliability and validity of the constructs. Hayes process was employed to test the structural model.FindingsOur study revealed that procurement capabilities and procurement planning directly improve project success in the construction sector in Ghana. We found procurement planning acts as a pathway for achieving greater success in construction projects.Originality/valueThis study is among the very few attempts to demonstrate how project success could be enhanced through developing procurement capabilities for effective procurement planning. Theoretically, this study is among the first attempts to theorise the effect of procurement capabilities and planning on project success from the human capital perspective. Our findings also offer practical insight to practitioners in the construction setting by emphasising the need to pay crucial attention to capabilities and planning in the quest to enhance project success in the construction setting. The findings indicate that building capabilities alone is not enough; rather, the ability to deploy such capabilities for effective procurement planning is necessary for driving project success.
Phenolic changes in propolis during in vitro digestion and cytotoxic effects on human cancer cell lines
Authors: Mutlu Ceren , Demir Zeynep , Özkan Aysun , Erbaş Mustafa 
Published: September 2024

PurposeThis study aimed to evaluate the compositional changes and bioaccessibility of phenolics and antioxidants in propolis during in vitro digestion as well as the cytotoxic effects of digested propolis on various cancer cell lines.Design/methodology/approachSix propolis samples were obtained and subjected to in vitro oral, gastric and intestinal digestion. Both digested and undigested samples were analyzed for their total phenolic, flavonoid and antioxidant activities. Additionally, changes in phenolic composition in the in vitro digestion system were revealed by the HPLC-DAD system. The cytotoxic effects of the digested samples were assessed on lung (A549, H1299), skin (A431), liver (Hep-G2) and colon (Caco-2) cancer cells as well as on fibroblast (Bj) cells.FindingsThe mean bioaccessibility values of phenolic and flavonoid compounds were found to be less than 35 and 24%, respectively, while the TEAC and CUPRAC antioxidant results ranged between 225.08–649.04 and 398.68–1552.28 µmol TE/g, respectively. The release of p-coumaric, ferulic, 3,4-dimethoxycinnamic acids, naringenin, pinocembrin and chrysin increased progressively from the oral to the intestinal stage. The cytotoxic effects of samples on cell lines were ranked, based on IC50 results, as A431 > Hep-G2 > Caco-2 > A549 > H1299 > Bj.Originality/valuePropolis has been recognized for centuries as a natural remedy, and numerous studies have explored its bioactive components. However, no studies have previously examined the changes in the phenolic compositions of propolis samples during digestion or their cytotoxic effects on cancer cells. Therefore, this study provides novel insights and an approach to the existing literature on this topic.Graphical abstract
Sustainability and software development projects: leadership, core self-evaluation and empowerment as critical success factors
Authors: Piwowar-Sulej Katarzyna , Iqbal Qaisar 
Published: September 2024

Purpose
The purpose of this paper is to integrate job demands–resources theory with core self-evaluation theory to examine how and when sustainable project leadership stimulates sustainable project performance. Psychological empowerment is used as a mechanism between sustainable project leadership and sustainable project performance, whereas core self-evaluation acts as a moderator between sustainable project leadership and psychological empowerment.

Design/methodology/approach
This study adopts a time-lagged two-phase approach to collecting data from 257 software engineers working in medium-sized and large companies in the Polish financial sector.

Findings
This study reveals the direct and indirect (through psychological empowerment) effects of sustainable project leadership on sustainable project performance. It also confirms that the “sustainable project leadership–psychological empowerment” relationship strengthens with increasing level of project team members’ core self-evaluation.

Originality/value
This article explores a unique research framework. It significantly enriches the literature on sustainable project management, increasing the understanding of effective leadership practices that address the needs of software engineering teams to support sustainable project performance.
Exploring the impact of job satisfaction on turnover intention among professionals in the construction industry
Authors: Zhang Shang , Wang Jinpeng , Ke Yongjian , Li Nan , Su Zhenwen 
Published: September 2024

PurposeTurnover intention is a critical predictor of an employee’s turnover behaviour. A high level of turnover rate significantly affects the productivity and morale of an enterprise. Previous research has indicated that job satisfaction plays a critical role in influencing an employee's turnover intention, but the underlying factors related to job satisfaction remain under-explored, which impedes the development of effective strategies for reducing turnover intention. In addition, little research examined job satisfaction and turnover intention in the context of the COVID-19 pandemic, specifically in the Chinese construction industry. This study aims to investigate the impact of job satisfaction on turnover intention among professionals in the construction industry.Design/methodology/approachA questionnaire survey was employed to collect viewpoints from 449 professionals in the Chinese construction industry, followed by descriptive analysis, correlation analysis and structural equation modelling analysis to derive results.FindingsThe findings indicate that professionals in the industry generally have a slightly high level of job satisfaction while a slightly low level of turnover intention in the special period of the pandemic outbreak. Leadership and management, training and career development and interpersonal relationships are critical underlying factors leading to their turnover intention. Although demographic factors have no moderating effect between job satisfaction and turnover intention, among them, age, marital status and years of working experience have strongly positive relationships with job satisfaction while significantly negative relationships with turnover intention.Originality/valueThe findings provide valuable insights to fully understand the critical factors leading to turnover intention from the perspective of job satisfaction, which is helpful in developing effective measures to address the turnover problems for enterprises in the Chinese construction industry and those industries with similar characteristics in other regions.
Retail therapy? The role of positive body image in women’s clothing experiences and preferences for in-store shopping environments
Authors: Seekis Veya , Yager Zali , Paas Karlien 
Published: September 2024

PurposeDespite the online shopping trend, many women still prefer in-store experiences for trying on and buying clothes. The body positivity movement endorsed by many brands implies that all women, even those with lower body appreciation, should feel included in this setting. However, studies have yet to quantitatively explore the mediating role of women’s positive body image between clothing size and in-store experiences. To address this gap, this study examined the in-store experiences of 642 women from largely Western nations (Mage = 45.96, standard deviation (SD) = 9.31) who self-reported as straight-, mid- and plus-sizes and the mediating role of body appreciation.Design/methodology/approachParticipants completed online questionnaires with measures including clothing size, body appreciation, in-store experiences and preferences for in-store changes.FindingsWomen of mid-size and plus-size were more likely than women of straight-size to report lower body appreciation, which led to a greater desire for guidance from staff about styles but less likelihood to approach them, higher discomfort going up a size and lower confidence trying on clothes. In contrast, straight-size women generally felt more comfortable and confident in-store clothes shopping. A direct link between clothing size and lower purchase intentions without in-store representation was found; however, body appreciation did not mediate this link. Preferences for in-store changes included better support from sales staff and more inclusive imagery.Originality/valueThis study indicates that in-store clothes shopping may not feel like retail therapy for women who identify as mid-size or plus-size and experience low body appreciation. It highlights the need for comprehensive reform within the fashion retail industry by prioritizing inclusivity through better staff support and in-store representation for all sizes.
Transitioning from inhibition to contextual emergence: investigating the mechanisms underlying the marginalization of county-level public libraries in China
Authors: Wang Zijian , Xiao Ximing , Fu Shiwei , Shi Qinggong 
Published: September 2024

PurposeThis study aims to uncover the mechanisms behind the marginalization of county-level public libraries.Design/methodology/approachThe research surveyed 25 counties in central China, including Hubei, Chongqing, Hunan, and Guizhou provinces. Semi-structured interviews were conducted with library directors and deputy directors, focusing on main and branch library construction, cultural inclusivity, library assessment, and digital services.FindingsContributing factors to library marginalization were identified as economic pressure, institutional domain, longstanding issues, organizational entity, and societal misconceptions. Building on this, the study introduces the HBAC model to explain county-level public library marginalization. Considering the actual social context of these libraries, the article proposes a “3 + 1” approach to mitigate their marginalization.Originality/valueThe research methodology, analysis process, theoretical model, and recommendations provided could shed light on academic research and practical exploration in the field of public libraries globally.