bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co‐surgeons in breast reconstructive microsurgery: What do they bring to the table?
Authors: Haddock Nicholas T. , Kayfan Samar , Pezeshk Ronnie A. , Teotia Sumeet S. 
Published: July 2017

AbstractIntroductionCurrent research within other surgical specialties suggests that a co‐surgeon approach may reduce operative times and complications associated with complex bilateral procedures, possibly leading to improved patient and surgical outcomes. We sought to evaluate the role of the co‐surgery team and its development in free flap breast reconstruction.MethodsA retrospective review of free‐flap breast reconstruction by two surgeons from 2011 to 2016 was conducted. We analyzed 128 patients who underwent bilateral‐DIEP breast. Surgical groups were: single‐surgeon reconstruction (SSR; 35 patients), co‐surgery where both surgeons are present for entire reconstruction (CSR‐I; 69 patients), and co‐surgery reconstruction where co‐surgeons appropriately assist in two concurrent or staggered cases (CSR‐II; 24 patients). Efficiency data collected was OR time and patient length‐of‐stay (LOS). The rate of flap‐failure, return to OR, infection, wound breakdown, seroma, hematoma, and PE/DVT were compared.ResultsSingle‐surgeon reconstruction had significantly longer OR time (678 vs. 485 min, P < .0001), LOS (5 vs. 3.9 days, P < .001), higher wound occurrences of the umbilical site that required surgical correction [11.4 percent (n = 4) vs. 1.5% (n = 1); P < .043] compared to CSR‐I. Similarly, SSR had significantly longer average OR time (678 vs. 527 min P < .0001), average LOS (5 vs. 4 days, P = .0005) when compared with CSR‐II. There were no total increased patient related complications associated with co‐surgery (CSR‐I or II).ConclusionThe addition of a co‐surgeon, even with concurrent surgery, reduces operative time, average patient LOS, and postoperative complications. This work lends a strong credence that co‐surgery model is associated with increased operative efficiency.
A revised model for coping with advanced cancer. Mapping concepts from a longitudinal qualitative study of patients and carers coping with advanced cancer onto Folkman and Greer's theoretical model of appraisal and coping
Authors: Roberts Diane , Calman Lynn , Large Paul , Appleton Lynda , Grande Gunn , Lloyd‐Williams Mari , Walshe Catherine 
Published: July 2017

AbstractObjectiveTo explore whether the Folkman and Greer theoretical model of appraisal and coping reflects the processes used by people living with advanced cancer.MethodsInterview data from a longitudinal qualitative study with people with advanced (stage 3 or 4) cancer (n = 26) were mapped onto the concepts of the Folkman and Greer theoretical model. Qualitative interviews conducted in home settings, 4‐12 weeks apart (n = 45) examined coping strategies, why people thought they were effective, and in what circumstances. Interviews were coded and analysed using techniques of constant comparison.ResultsMapping coping strategies clearly onto the problem‐ or emotion‐focused elements of the model proved problematic. Fluctuating symptoms, deterioration over time, and uncertain timescales in advanced cancer produce multiple events simultaneously or in quick succession. This demands not only coping with a single event but also frequent repositioning, often to an earlier point in the coping process. In addition, there is substantial ongoing potential for some degree of distress rather than purely “positive emotion” as the final stage in the process is death with several points of permanent loss of capability in the interim.ConclusionsThe Folkman and Greer theoretical model is helpful in deconstructing the discrete “problem‐focused” or “emotion‐focused” coping mechanisms participants describe, but its formulation as a linear process with a single, positive, outcome is insufficiently flexible to capture the evolution of coping for people with advanced cancer.
Comparative proteomic study of early hypoxic response in the cerebral cortex of rats submitted to two different hypoxic models
Authors: Ovelleiro David , Blanco Santos , Hernández Raquel , Peinado María Ángeles 
Published: July 2017

PurposeThe present study analyses and compares the cortical brain proteomic profiles of two different models of cerebral hypoxic insult in rats (HH: hypobaric hypoxia and HHI: ischemia followed by hypobaric hypoxia) in an attempt to describe the alterations of the early molecular hypoxic adaptive response underlying each one.Experimental DesignA quantitative proteomic profile of left‐brain cortices of rats under HH, HHI, and control conditions was determined using isobaric labeling (Tandem Mass Tag™) on the protein extracts from pools of five individuals. Data are available via ProteomeXchange with identifier PXD004091.ResultsAltogether, 339 proteins were confidently quantified, 99 of them showing significant variations in the hypoxic conditions with respect to the control. The HHI model presents a global effect of protein downregulation while HH produces an overall increase of the protein levels. While HH mainly affecting oxidative and energetic metabolism, HHI also interferes with synaptic transmission, neurotransmitter secretion, substantia nigra development, and triggers apoptosis through mitochondrial pathway.Conclusions and Clinical RelevanceThe findings obtained show an overview of protein alterations under two hypoxic models of different aetiology and provide a basis for more detailed studies in order to unravel new specific mechanisms and therapies for hypoxic pathologies.
Synthesis and Optical Properties of Fluorescent Switchable Silica Nanoparticles Covered with Copolymers Consisting of Diarylethene and Fluorene Derivatives
Authors: Shimizu Katsuya , Kobatake Seiya 
Published: July 2017

AbstractSilica nanoparticles covered with random copolymers consisting of diarylethene monomer (DE) and fluorene monomer (FL) (SNP‐poly(DE‐co‐FL)) were designed and synthesized by reversible addition‐fragmentation chain transfer (RAFT) copolymerization of DE and FL initiated from a RAFT agent immobilized on the surface of silica nanoparticle. SNP‐poly(DE‐co‐FL) and silica‐free polymer (poly(DE‐co‐FL)), which are soluble in tetrahydrofuran, underwent reversible photoisomerization of DE moieties upon alternating irradiation with ultraviolet and visible light. They exhibited fluorescence ON/OFF switching between fluorescence ON state of FL in the open‐ring form of DE and fluorescence OFF state by an efficient Förster/fluorescence resonance energy transfer from the excited FL not only in the same polymer chain but also in the surrounding polymer chains to the closed‐ring form of DE. Diarylethene‐fluorene dyad (DE‐FL) was synthesized to compare with fluorescence ON/OFF switching efficiencies of SNP‐poly(DE‐co‐FL) and poly(DE‐co‐FL). The closed‐ring isomers of DE in DE‐FL, poly(DE‐co‐FL), and SNP‐poly(DE‐co‐FL) were found to quench fluorescence of 0.78, 6.3, and 15.6 FL moieties, respectively. Thus, fluorescence switching efficiency of SNP‐poly(DE‐co‐FL) was 2.5 times higher than poly(DE‐co‐FL) and 20 times higher than DE‐FL. Furthermore, the closed‐ring isomer of DE in SNP‐poly(DE‐co‐FL) was found to quench 6.3 FL moieties in the same polymer chain and 9.3 FL moieties in four polymer chains in the neighborhood.
A Facile Synthesis of LaFeO3‐Based Perovskites and Their Application towards Sensing of Neurotransmitters
Authors: Vijayaraghavan Thiruvenkadam , Sivasubramanian Ramanathan , Hussain Shamima , Ashok Anuradha 
Published: July 2017

AbstractLanthanum ferrite (LaFeO3) was prepared from its oxide precursors using solid state synthesis technique. Structural analysis indicate that the synthesized perovskite is phase pure having orthorhombic crystal structure with space group Pnma (62) and cell dimensions a=5.5392 Å, b=7.8573 Å, c=5.5584 Å. Morphological studies show aggregated spherical shaped nanoparticles having orthorhombic crystal structure with an average particle size of ∼ 50 nm. The LaFeO3 modified glassy carbon electrode (GCE) was studied to determine its electrocatalytic activity towards dopamine oxidation. It is seen that the LaFeO3/GCE showed excellent electrocatalytic activity with a manifold increase in oxidation current compared to bare GCE. The sensing was carried out using Differential Pulse Voltammetry (DPV) wherefrom a detection limit of 10 nM and two linear regimes from 10 μM to 100 μM and 120 μM to 180 μM was deduced. The influence of ascorbic acid and uric acid in the sensing of dopamine was investigated. The estimation of dopamine in human blood samples were analyzed with excellent recovery values.
The Effect of Catalysis on the Parameters of the Oxidation Reaction of Biodiesel
Authors: Angilelli Karina G. , Silva Lívia R. C. , Chendynski Letícia T. , da Silva Paulo R. C. , Borsato Dionisio 
Published: July 2017

AbstractMost commercial biodiesel is produced with homogeneous basic catalyst however, environmental and economically, the use of heterogeneous catalysis is potentially advantageous since they can be reused. This work aimed to evaluate the influence of homogeneous and heterogeneous catalysis on the oxidative stability of biodiesel by the determination of the kinetic and thermodynamic parameters of the oxidation reactions. The catalyst produced with a mixture of MgO and KOH (HetA) led to the production of biodiesel with the highest reaction yield, ester content and oxidative stability. Among the oxidation reaction parameters evaluated, the catalyst HetA and sodium methoxide showed the best results in terms of activation energy and activation enthalpy values. Both catalysts produced biodiesel with good results in terms of oxidative stability, though the HetA catalyst stands out for presenting the best results and underlines the advantages of employing a heterogeneous process.
Molecular Insights into Protein‐Polyphenols Aggregation: A Dynamic and Topological Description
Authors: Petelski André N. , Pamies Silvana C. , Benítez Elisa I. , Rovaletti María M. Lataza , Sosa Gladis L. 
Published: July 2017

AbstractProtein‐polyphenols interactions are of greatest interest in several fields like food technology and leather industry. Also, it is thought that these interactions are responsible for the undesired phenomenon of colloidal turbidity. However, there is sparse information about the molecular implications leading to this phenomenon. In this study, Molecular Dynamic (MD) simulations in conjunction with the analysis of the topology of the electron density are used to study protein/polyphenol interactions in a model system which consists of a ternary mixture of water, the flavonoids Catechin and Procianidin B3 and proline pentapeptides. After 50 ns of simulation, root mean square deviation, root mean square fluctuation and number of hydrogen bonds were calculated. Information about the intermolecular interactions that drive the assembly of colloidal complexes has been obtained by the analysis of the electron charge density. Results show the formation of a stable adduct, with a very complex network of conventional and non‐conventional hydrogen bonds. This study has also shown the significance of C‐H⋅⋅⋅O and C‐H⋅⋅⋅π interactions in the phenomenon of colloidal turbidity.
Immobilization of Quantum Dots on Fluorescent Graphene Oxide for Ratiometric Fluorescence Detection of Copper Ions
Authors: Zhu Houjuan , Xu Hongda , Yu Huan , Zhang Kui , Hayat Tasawar , Alsaedi Ahmed , Wang Suhua 
Published: July 2017

AbstractGraphene oxide with stable fluorescence has been synthesized and utilized to support and functionalize quantum dots for dual‐emissive nanostructure construction. The two emissions from graphene oxide and quantum dots are differently and independently responsive to copper ions (Cu2+). The blue fluorescence of graphene oxide is very stable against Cu2+, whereas the red fluorescence from quantum dots can be selectively quenched, inducing the composite fluorescent color change from bright red to blue. Such a novel nanocomposite can be applied for selective and sensitive determination of Cu2+. For practical application, the graphene based nanohybrid has been immobilized in polymer film to fabricate fluorescence test strip for Cu2+. A visual detection limit of 0.1 μM for the film test strip has been estimated and shows the potential application for on‐site visual determination of Cu2+ with no need for elaborate equipment.
Synthesis of 1, 5‐ Disubstituted Tetrazole via Ugi Azide Reaction: An Asymmetric Induction Approach
Authors: Santhosh L. , Nagamangala Sagar R. , Thimmalapura Vishwanatha M. , Vommina Sureshbabu V. 
Published: July 2017

AbstractThe Ugi‐azide reaction of an enantiopure amino acid derived isocyanides, amino acid esters, aldehydes and TMS‐N3 in MeOH:THF solvent system at 50 °C yielded peptidomimetics comprising tetrazole as amide bond isostere. Both N‐terminal (α‐isocyanoesters) and C‐terminal isocyanides (Nβ‐Cbz‐protected amino alkyl isocyanides) have been employed to yield diversified tetrazole peptidomimetics, having the possibility of further derivatization through either N‐ or C‐terminal chain elongation. Ugi‐azide reaction is a isocyanide based multi‐component reaction (IMCR), as a result, change in amino acid derived isocyanides had given structurally diverse products of biological interest. Good yields of products were obtained after column purification and were stable for shelf storage. The products are novel and were well characterized by Mass, 1H NMR and 13C NMR spectral studies. The present method offers several advantages such as one‐pot simple procedure, high yields and easy purification of products.
Iodine‐Doped Graphene with Opportune Interlayer Spacing as Superior Anode Materials for High‐Performance Lithium‐Ion Batteries
Authors: Chen Jie , Wu Chao , Tang Chun , Zhao Wenxi , Xu Maowen , Li Chang Ming 
Published: July 2017

AbstractIn this article, the iodine doped graphene (I‐RGO) materials with different interlayer spacings were prepared by a one‐pot hydrothermal method, and the direct effect of the interlayer spacing on the electrochemical properties was studied as the anode materials of lithium ion batteries for the first time. The results show that the I‐RGO0.01 anode with the optimal interlayer spacing delivers a high specific capacity of 958.1 mAh g−1 after 390 cycles at the current density of 1 A g−1. Furthermore, at the high current density of 2 and 4 A g−1, the high‐rate capacities of 525.8 and 343.1 mAh g−1 could still be achieved for the I‐RGO0.01 electrode after 1045 and 2000 cycles with the small capacity decay rates of 0.032 % and 0.024 % per cycle, respectively. The excellent electrochemical performance is mainly attributed to the expanded interlayer distance of graphene, which is capable of improving the electrode/electrolyte contact region and accelerating the difussion and surface absorption of lithium ion.
The effects of traditional, superset, and tri-set resistance training structures on perceived intensity and physiological responses
Authors: Weakley Jonathon J. S. , Till Kevin , Read Dale B. , Roe Gregory A. B. , Darrall-Jones Joshua , Phibbs Padraic J. , Jones Ben 
Published: July 2017

Abstract
Purpose
Investigate the acute and short-term (i.e., 24 h) effects of traditional (TRAD), superset (SS), and tri-set (TRI) resistance training protocols on perceptions of intensity and physiological responses.

Methods
Fourteen male participants completed a familiarisation session and three resistance training protocols (i.e., TRAD, SS, and TRI) in a randomised-crossover design. Rating of perceived exertion, lactate concentration ([Lac]), creatine kinase concentration ([CK]), countermovement jump (CMJ), testosterone, and cortisol concentrations was measured pre, immediately, and 24-h post the resistance training sessions with magnitude-based inferences assessing changes/differences within/between protocols.

Results
TRI reported possible to almost certainly greater efficiency and rate of perceived exertion, although session perceived load was very likely lower. SS and TRI had very likely to almost certainly greater lactate responses during the protocols, with changes in [CK] being very likely and likely increased at 24 h, respectively. At 24-h post-training, CMJ variables in the TRAD protocol had returned to baseline; however, SS and TRI were still possibly to likely reduced. Possible increases in testosterone immediately post SS and TRI protocols were reported, with SS showing possible increases at 24-h post-training. TRAD and SS showed almost certain and likely decreases in cortisol immediately post, respectively, with TRAD reporting likely decreases at 24-h post-training.

Conclusions
SS and TRI can enhance training efficiency and reduce training time. However, acute and short-term physiological responses differ between protocols. Athletes can utilise SS and TRI resistance training, but may require additional recovery post-training to minimise effects of fatigue.
Models of care for traumatically injured patients at trauma centres in British Columbia: variability and sustainability
Authors: Tuyp Benjamin , Hassani Kasra , Constable Lisa , Haegert Joseph 
Published: July 2017

AbstractBackgroundSuccessful trauma systems employ a network of variably-resourced hospitals, staffed by experienced providers, to deliver optimal care for injured patients. The “model of care”—the manner by which inpatients are admitted and overseen, is an important determinant of patient outcomes.ObjectivesTo describe the models of inpatient trauma care at British Columbia’s (BC’s) ten adult trauma centres, their sustainability, and their compatibility with accreditation guidelines.MethodsQuestionnaires were distributed to the trauma medical directors at BC’s ten Level I-III adult trauma centres. Follow-up semi-structured interviews clarified responses.ResultsThree different models of inpatient trauma care exist within BC. The “admitting trauma service” was a multidisciplinary team providing exclusive care for injured patients. The “on-call consultant” assisted with Emergency Department (ED) resuscitation before transferring patients to a non-trauma admitting service. The single “short-stay trauma unit” employed on-call consultants who also oversaw a 48-hour short-stay ward.Both level I trauma centres utilized the admitting trauma service model (2/2). All Level II sites employed an on-call consultant model (3/3), deviating from Level II trauma centre accreditation standards. Level III sites employed all three models in similar proportions. None of the on-call consultant sites believed their current care model was sustainable. Inadequate compensation, insufficient resources, and difficulty recruiting physicians were cited barriers to sustainability and accreditation compliance.ConclusionsThree distinct models of care are distributed inconsistently across BC’s Level I-III trauma hospitals. Greater use of admitting trauma service and short-stay trauma unit models may improve the sustainability and accreditation compliance of our trauma system.
Environmental Surfaces in Healthcare Facilities are a Potential Source for Transmission ofCandida aurisand OtherCandidaSpecies
Authors: Piedrahita Christina T. , Cadnum Jennifer L. , Jencson Annette L. , Shaikh Aaron A. , Ghannoum Mahmoud A. , Donskey Curtis J. 
Published: July 2017

Contaminated surfaces have been implicated as a potential route for dissemination of the emerging multidrug-resistant fungal pathogenCandida auris. In laboratory testing,C. aurisand otherCandidaspecies persisted for 7 days on moist or dry surfaces.Candidaspecies were recovered frequently from the hospital environment, particularly from moist surfaces.Infect Control Hosp Epidemiol2017;38:1107–1109
Surgical Site Infections After Liver Transplantation: Prospective Surveillance and Evaluation of 250 Transplant Recipients in Canada
Authors: Natori Yoichiro , Kassar Rawan , Iaboni Aled , Hosseini-Moghaddam Seyed M. , Vu James , Husain Shahid , Renner Eberhard L. , Grant David , Rotstein Coleman 
Published: July 2017

OBJECTIVETo evaluate the incidence of surgical-site infections (SSIs) in a cohort of liver transplant recipients and to assess risk factors predisposing patients to these infections.DESIGNProspective observational cohort study.SETTINGSingle transplant center in Canada.PATIENTSPatients who underwent liver transplantation between February 2011 and August 2014.METHODSMultivariate logistic regression was used to identify independent risk factors for SSIs in liver transplant patients.RESULTSWe enrolled 250 liver transplant recipients. The recipients’ median age at the time of transplantation was 56 years (range, 19–70 years), and 166 patients (66.4%) were male. Moreover, 47 SSIs were documented in 43 patients (17.2%). Organ-space, superficial, and deep SSIs were noted in 29, 7, and 3 patients, respectively. In addition, 2 patients developed superficial and organ-space SSIs, and another 2 patients were found to have deep as well as organ-space infections. In total, we identified 33 organ-space SSIs (70.2%), 9 superficial SSIs (19.1%), and 5 deep SSIs (10.6%). Factors predictive of SSIs by multivariate analysis were duct-to-duct anastomosis (odds ratio [OR], 3.88; 95% CI, 1.85–8.13; P<.001) and dialysis (OR, 3.57; 95% CI, 1.02–12.50; P=.046). Of the 66 organisms isolated in both deep and organ-space SSIs, 55 (83%) were resistant to cefazolin.CONCLUSIONSOrgan-space SSIs are a common complication after liver transplantation. Duct-to-duct anastomosis and dialysis were independent risk factors associated with SSIs. Appropriate perioperative prophylaxis targeting patients with duct-to-duct anastomosis and dialysis while simultaneously providing optimum coverage for the potential pathogens causing SSIs is warranted.Infect Control Hosp Epidemiol 2017;38:1084–1090
Epidemiologic Review of Veterans Health Administration Patients with Isolation of Nontuberculous Mycobacteria after Cardiopulmonary Bypass Procedures
Authors: Oda Gina , Ryono Russell , Lucero-Obusan Cynthia , Schirmer Patricia , Shanawani Hasan , Jacobs Katrina , Holodniy Mark 
Published: July 2017

We evaluated the isolation of postoperative nontuberculous mycobacteria (NTM) associated with heater-cooler devices (HCDs) used during cardiopulmonary bypass (CPB) surgery in the Veterans Health Administration from January 1, 2010, to December 31, 2016. In more than 38,000 CPB procedures, NTM was isolated in 111 patients; 1 Mycobacterium chimaera mediastinitis case and 1 respiratory isolate were found.Infect Control Hosp Epidemiol 2017;38:1103–1106
Gene cloning and difference analysis of vitellogenin in Neoseiulus barkeri (Hughes)
Authors: Ding L. , Chen F. , Luo R. , Pan Q. , Wang C. , Yu S. , Cong L. , Liu H. , Li H. , Ran C. 
Published: July 2017

AbstractNeoseiulus barkeri (HUGHES) is the natural enemy of spider mites, whiteflies and thrips. Screening for chemically-resistant predatory mites is a practical way to balance the contradiction between the pesticide using and biological control. In this study, the number of eggs laid by fenpropathrin-susceptible and resistant strains of N. barkeri was compared. Additionally, we cloned three N. barkeri vitellogenin (Vg) genes and used quantitative real-time polymerase chain reaction to quantify Vg expression in susceptible and resistant strains. The total number of eggs significantly increased in the fenpropathrin-resistant strain. The full-length cDNA cloning of three N. barkeri Vg genes (NbVg1, NbVg2 and NbVg3) revealed that the open reading frames of NbVg1, NbVg2 and NbVg3 were 5571, 5532 and 4728 bp, encoding 1856, 1843 and 1575 amino acids, respectively. The three N. barkeri Vg possessed the Vitellogenin-N domain (or lipoprotein N-terminal domain (LPD_N)), von Willebrand factor type D domain (VWD) and the domain with unknown function 1943 (DUF1943). The NbVg1 and NbVg2 expression levels were significantly higher in the resistant strain than in the susceptible strain, while the NbVg3 expression level was lower in the resistant strain. Thus, we speculate that the increased number of eggs laid by the fenpropathrin-resistant strain of N. barkeri may be a consequence of changes in Vg gene expression.