bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low Incidence of End-Stage Renal Disease in Childhood-Onset Type 1 Diabetes Followed for Up to 42 Years
Authors: Gagnum Vibeke , Saeed Maryam , Stene Lars C. , Leivestad Torbjørn , Joner Geir , Skrivarhaug Torild 
Published: October 2017

OBJECTIVE
End-stage renal disease (ESRD) is one of the most severe complications in type 1 diabetes. We aimed to estimate the cumulative incidence of ESRD in individuals with childhood-onset type 1 diabetes followed for up to 42 years.

RESEARCH DESIGN AND METHODS
Data were based on the nationwide, population-based Norwegian Childhood Diabetes Registry and included case patients with new-onset type 1 diabetes (age &lt;15 years) who had received a diagnosis during the periods 1973–1982 and 1989–2012. Follow-up took place until the development of ESRD, death, emigration, or 30 November 2015. We estimated the cumulative incidence of ESRD by linking to the Norwegian Renal Registry.

RESULTS
Among the 7,871 patients, representing 147,714 person-years of follow-up, ESRD developed in 103 individuals (1.3%). The mean time from the diagnosis of diabetes to the development of ESRD was 25.9 years (range 12.7–39.1). The cumulative incidence of ESRD was 0.7% (95% CI 0.4–1.0) at 20 years’ diabetes duration, 2.9% (2.3–3.7) at 30 years’ duration, and 5.3% (4.3–6.5) at 40 years’ duration. The risk of the development of ESRD was lower in women than in men (hazard ratio [HR] 0.61; 95% CI 0.41–0.91) and higher in individuals in whom diabetes had been diagnosed at 10–14 years of age compared with those in whom it was diagnosed before 10 years of age (HR 1.29; 1.06–1.56). We did not identify any significant difference in the risk of the development of ESRD between those in whom diabetes was diagnosed in 1973–1982 and in 1989–2012 (HR 0.80; 0.45–1.45).

CONCLUSIONS
We report a very low incidence of ESRD among patients with childhood-onset diabetes in Norway. The risk was lower in women compared with men and in individuals in whom diabetes was diagnosed at a younger age.
TCF7L2 Genetic Variants Contribute to Phenotypic Heterogeneity of Type 1 Diabetes
Authors: Redondo Maria J. , Geyer Susan , Steck Andrea K. , Sosenko Jay , Anderson Mark , Antinozzi Peter , Michels Aaron , Wentworth John , Xu Ping , Pugliese Alberto ,   the Type 1 Diabetes TrialNet Study Group
Published: October 2017

OBJECTIVE
The phenotypic diversity of type 1 diabetes suggests heterogeneous etiopathogenesis. We investigated the relationship of type 2 diabetes–associated transcription factor 7 like 2 (TCF7L2) single nucleotide polymorphisms (SNPs) with immunologic and metabolic characteristics at type 1 diabetes diagnosis.

RESEARCH DESIGN AND METHODS
We studied TrialNet participants with newly diagnosed autoimmune type 1 diabetes with available TCF7L2 rs4506565 and rs7901695 SNP data (n = 810; median age 13.6 years; range 3.3–58.6). We modeled the influence of carrying a TCF7L2 variant (i.e., having 1 or 2 minor alleles) on the number of islet autoantibodies and oral glucose tolerance test (OGTT)–stimulated C-peptide and glucose measures at diabetes diagnosis. All analyses were adjusted for known confounders.

RESULTS
The rs4506565 variant was a significant independent factor of expressing a single autoantibody, instead of multiple autoantibodies, at diagnosis (odds ratio [OR] 1.66 [95% CI 1.07, 2.57], P = 0.024). Interaction analysis demonstrated that this association was only significant in participants ≥12 years old (n = 504; OR 2.12 [1.29, 3.47], P = 0.003) but not younger ones (n = 306, P = 0.73). The rs4506565 variant was independently associated with higher C-peptide area under the curve (AUC) (P = 0.008) and lower mean glucose AUC (P = 0.0127). The results were similar for the rs7901695 SNP.

CONCLUSIONS
In this cohort of individuals with new-onset type 1 diabetes, type 2 diabetes–linked TCF7L2 variants were associated with single autoantibody (among those ≥12 years old), higher C-peptide AUC, and lower glucose AUC levels during an OGTT. Thus, carriers of the TCF7L2 variant had a milder immunologic and metabolic phenotype at type 1 diabetes diagnosis, which could be partly driven by type 2 diabetes–like pathogenic mechanisms.
Manajemen Perkuliahan Jurusan Pendidikan Ekonomi
Authors: Tripalupi Lulup Endah , Meitrina Made Ary 
Published: October 2017

Keberhasilan suatu perguruan tinggi dalam menyelenggarakan kegiatan perkuliahan memerlukan manajemen/pengelolaan yangbaik .Manajemen/pengelolaanakan sarana dan prasarana pendukung perkuliahan yang memadai bertujuan agar program-program perkuliahan yang sudah direncanakan dapat berjalan dengan lancar, teratur, tertib dan efisien. Hasil penelitian menunjukkan bahwa manajemen perkuliahan di Jurusan Pendidikan Ekonomi telah tertata dengan baik hal ini dapat ditunjukkan dengan adanya kesesuaian antara harapandan yang dirasakan mahasiswa terhadap pelayanan perkuliahan pada masing-masing dimensi kualitas pelayanan.Staf dosen dan staf administrasi telah menjalankan fungsi dan tugasnya dengan baik sudah sesuai dengan harapan mahasiswa Namun pada hal-hal tertentu seperti, kenyamanan ruang kuliah, kejelasan peraturan jurusan yang masih perlu ditingkatkan
Pelatihan Kewirausahaan Implementasi Sistem Akuntansi dalam Rangka Meningkatkan Kualitas Laporan Keuangan UMKM
Authors: Diatmika I Putu Gede , Yuniarta Gede Adi , Yudantara I Gede Agus Pertama 
Published: October 2017

Usaha Mikro, kecil dan menengah (UMKM) mempunyai kedudukan dan fungsi yang penting yang secara bersama-sama dengan badan usaha milik negara atau swasta melakukan berbagai usaha demi tercapainya kesejahteraan bagi masyarakat. Fungsi UMKM yaitu mempersatukan, mengarahkan dan mengembangkan daya kreasi, daya cipta, serta daya usaha rakyat, terutama mereka yang serba terbatas kemampuan ekonominya agar mereka dapat turut serta dalam kegiatan perekonomian. Informasi akuntansi dipergunakan untuk menilai aktivitas manajemen dalam mengelola asset yang dipercayakan kepadanya (fungsi stewardship) serta dipergunakan pula sebagai alat pengambilan keputusan oleh pihak-pihak yang mempergunakannya. UMKM mengalami kendala dalam pemahaman penerapan akuntansi dalam operasional usahanya, upaya yang mereka lakukan adalah dengan meningkatkan kemampuan tenaga akuntansi mereka melalui pelatihan-pelatihan yang dilakukan secara insidental baik yang dilakukan oleh instansi terkait maupun melalui kegiatan yang dilakukan oleh perguruan tinggi. Namun upaya yang mereka lakukan belum menghasilkan hasil yang opimal, ditambah lagi dengan tingkat mutasi pegawai yang cukup tinggi, dimana pegawai yang sudah dilatih terkadang berpindah tempat kerja. Permasalahan ini menjadi masalah laten dan terjadi berulang-ulang sehingga sangat mengganggu operasional UMKM sehari-hari. Untuk dapat mencapai tujuan kegiatan maka metode yang dilakukan adalah berupa pendampingan kepada 20 UMKM. Pendampingan ini dilakukan dengan cara memberikan perangkat simulasi akuntansi berbasis multimedia kepada UMKM kemudian diberikan penjelasan cara penggunanya. Kegiatan pendampingan ini diawali kegiatan pembekalan penggunaan perangkat. Setelah itu dilakukan monitoring pemanfaatan perangkat simulasi tersebut. Kegiatan akhir yang dilakukan adalah evaluasi terhadap kebermanfaatan perangkat terhadap peningkatan kemampuan UMKM dalam menyusun laporan keuangan.
Pengembangan Sistem Informasi Manajemen Pengelolaan Dan Penerbitan Jurnal Ilmiah Jurusan Akuntansi Program S1
Authors: Aristia Prayudi Made , Vijaya Diota Prameswari , Ekawati Luh Putu 
Published: October 2017

Penelitian ini bertujuan untuk mengembangkan suatu sistem informasi manajemen pengelolaan dan penerbitan Jurnal Ilmiah Akuntansi (JIA) Jurusan Akuntansi Program S1 yang efektif dalam rangka pencapaian status terakreditasi nasional. Data dikumpulkan melalui pengamatan langsung dan wawancara yang ditujukan kepada peneliti, editor dan mitra bebestari pada Jurnal Ilmiah Akuntansi (JIA) Universitas Pendidikan Ganesha dan pada organisasi Aliansi Pengelola Jurnal Ekonomi dan Bisnis Indonesia (ALJEBI). Data yang diperoleh selanjutnya dianalisis secara deskriptif untuk selanjutnya menjadi dasar pengembangan sistem yang dimaksud. Hasil penelitian menunjukkan bahwa Abstrak ditulis dalam Bahasa Indonesia dan Bahasa Inggris menggunakan huruf Bookman Old Style ukuran 10pt, spasi 1 dan dengan panjang teks maksimal 200 kata. Abstrak versi Bahasa Indonesia ditulis menggunakan Bahasa Indonesia baku dengan ejaan yang disempurnakan. Penulisan singkatan dan rumus matematika di dalam abstrak perlu dihindari. Dalam format satu paragraf, Abstrak memaparkan secara ringkas tentang masalah atau topik penelitian, tujuan penelitian, metode penelitian, hasil penelitian dan implikasi penelitian.
Pengaruh Lokasi dan Fasilitas Terhadap Kepuasan Pengguna Jasa Bongkar Muat Petikemas Pada PT Pelabuhan Indonesia IV (Persero) Cabang Merauke
Authors: Kana Tarsisius 
Published: October 2017

Penelitian ini bertujuan untuk mengetahui sebarapa besar pengaruh lokasi dan fasilitas terhadap kepuasan pengguna jasa. Lokasi memiliki indikator : akses, visibilitas, lalulintas dan fasilitas memiliki indikator : sifat dan tujuan organisasi, ketersediaan tanah dan kebutuhan ruang dan tempat, fleksibilitas, faktor estetis, masyarakat dan lingkungan sekitar, biaya konstruksi dan operasi sedangkan kepuasan pengguna jasa memiliki indikator : kepuasan pelanggan, dimensi kepuasan pelanggan, konfirmasi harapan, minat pembelian ulang, kesediaan untuk merekomendasikan, ketidakpuasan pelanggan. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan dengan menggunakan teknik pengolahan datan deskritif, teknik pengumpuluan data dengan wawancara, kuesioner dan studi kepustakaan. Teknik pengambilan sampel yang digunakan sampling incidental. Pengukuran menggunakan Skala Likert dan diolah menggunakan program hitung SPSS versi 23 untuk menghitung uji validitas dan uji releabilitas, menghitung uji hipotesis yaitu uji t, uji f dan koefisien determinasi. Hasil penelitian menunjukan variabel lokasi dan fasilitas secara bersama-sama mempunyai pengaruh positif terhadap kepuasan pengguna jasa pada PT Pelabuhan Indonesia IV (Persero) Cabang Merauke. Hal ini dapat dibuktikan dari hasil F hitung 39.984 > 3.11 dengan tingkat signifikasi 0.000 ≤ 0,05, maka Ho ditolak Ha diterima. dapat disimpulkan terdapat hubungan yang positif dan signifikan antara lokasi dan fasilitas terhadap kepuasan pengguna jasa bongkar muat petikemas pada PT Pelabuhan Indonesia IV (Persero) Cabang Merauke.
Model Tata Kelola Jurusan/PS Berbasis Kerangka Kualifikasi Nasional Indonesia (KKNI)
Authors: Yulianthini Ni Nyoman , Suci Ni Made 
Published: October 2017

Tujuan penelitian ini mengembangkan model tata kelola jurusan/PSberbasis KKNI. Penelitian dilakukan pada jurusan/PS manajemen, fakultas ekonomi Undiksha. Teknik pengumpulan data dengan wawancara, dokumentasi, kuesioner dan diskusi kelompok fokus terhadap pengelola jurusan/PS, pimpinan sdekanat, mahasiswa manajemen dan stake holders yang relevan. Hasil penelitian menunjukkan: 1) Jurusan/PS manajemen memilik kekuatan pada keilmuan manajemen SDM, keuangan dan pemasaran, softskill mahasiswa bidang akademis dan non akademis, pengelolaan dan dukungan keuangan serta kerjasama dengan asosiasi, instansi dan industri sedangkan kelemahannya nilai akreditasi jurusan/PSan B, kurangnya kerjasama baik nasional maupun internasional, porsi sumber pendanan dari mahasiswa, dan karya dosen masih. Aspek peluangprogram studi dengan semakin bertumbuhan industri dan perbankan, ketersediaan dana hibah penelitian, pengabdian, publikasi ilmiah, UU guru dan dosen, UU pendidikan Nasional, KKNI, Standar Nasional Pendidikan, dan kebijakan masyarakat ekonomi ASEAN sedangkan aspek ancaman: persaingan antar program studi manajemen, kualsifikasi dosen dan tuntutan pengguna lulusan.2)Pengembangan kurikulum jurusan/PSberbasis KKNI mensyaratkan: penyusunan deskripsi capaian pembelajarannya, kurikulum, pelaksanaan, dan pengevaluasian pelaksanaannya serta sistem penjaminan mutu internal 3)Tata kelola jurusan/PSberbasis KKNI menyangkut: organisasi, kepemimpinan, dan pengelolaan SDM, keuangan, sarana dan prasarana,kerjasama dan keberlanjutan program kegiatan dan jurusan/PS manajemen
KETENTUAN HUKUM TENTANG USIA CALON PESERTA DIDIK PENDIDIKAN DASAR BERDASARKAN SISTEM PENDIDIKAN NASIONAL DI INDONESIA (STUDI KASUS DI DAERAH KOTA DENPASAR)
Authors: Devi Salain Made Suksma Prijandhini 
Published: October 2017

Pendidikan dasar merupakan jenjang pendidikan awal yang diwajibkan di Indonesia berdasarkan sistem pendidikan nasional. Sistem pendidikan nasional mensyaratkan setiap warga Negara yang berusia 7 (tujuh) tahun sampai dengan 15 (lima belas) tahun wajib mengikuti pendidikan dasar. Pernyataan inilah yang membuat kerancuan dalam menetapkan batasan usia calon peserta didik pendidikan dasar di Indonesia. Sebagai contoh, di Daerah Kota Denpasar antara Sekolah Dasar (SD) Negeri dan Swasta menetapkan persyaratan yang berbeda mengenai batasan usia penerimaan calon peserta didiknya. SD-SD Negeri mensyaratkan calon peserta didiknya minimum berusia 7 (tahun) sedangkan SD-SD Swasta lebih fleksibel menetapkan batasan usia calon peserta didiknya. Pernyataan rentang usia wajib belajar pendidikan dasar pada Undang-Undang Sistem Pendidikan Nasional berbeda dengan peraturan perundangan di bidang pendidikan lainnya. Berdasarkan keadaan tersebut, terdapat permasalahan dalam penelitian ini, yaitu: Bagaimanakah ketentuan hukum mengenai usia calon peserta didik pendidikan dasar di Indonesia dan Bagaimanakah implementasinya pada Sekolah Dasar di Daerah Kota Denpasar. Penelitian ini berjenis normatif dengan didukung beberapa data primer. Bahan-bahan hukum dan data primer yang di dapat di lapangan akan dianalisis secara sistematis sehingga dapat menjawab 2 (dua) permasalahan dalam penelitian ini.Primary education is a first level education in Indonesia which has mandatory characteristic based on national education system. National education system is presupposing every citizens that 7 (seven) years old until 15 (fifteen) years old are obligatory to enroll the primary education. This statement is making confusion in determining the age limit for the students in Indonesia primary education. For example, public and private elementary schools in Denpasar determining different requirements of age limit for their students. Public elementary schools are presupposing their candidate students for minimum 7 (seven) years old whereas private elementary schools are more flexible in specifying requirements for their candidate students. The statement of age range of the compulsory education in the national education system act is different with the other education regulations. Based on those situations, there are problems in this research: How is the regulation of the age for the candidate students in Indonesia primary education and How about the implementation in the elementary schools that are situated in Denpasar. This research is normative which supported by some primary data. The legal materials and primary data that collected from the field are analyzed in systematically in order to answer 2 (two) problems in this research.
STRATEGI KOMUNIKASI PEMASARAN TERPADU EKOWISATA DI KEBUN RAYA EKA KARYA, BEDUGUL, BALI
Authors: Muntadliroh Muntadliroh 
Published: October 2017

Ecotourism of Bali Botanical Garden, Bedugul, Tabanana Regency,
Bali, has been able to increase the number of visitors from time to
time though it is still far from the optimum level. In 2010-2011 the number of visitors at Bali Botanical Gardens was counted for 368.927 people. Based on the data, visitors interest to visit Bali
Botanical Garden are still low. Facing this problem, integrated
marketing communication strategy is needed.This paper discusses
implementation of integrated marketing communication concept
created by Philip Kotler to the market ecotourism at Bali Botanical
Garden, by using case study for qualitative research.The results of
this analysis show that implementing this concept made a better
relationship between Bali Botanical Garden and its visitors, also
increasing quantity of its visitors.
PENGGUNAAN SITUS WEB HOTEL DAN “ONLINE TRAVEL AGENCY” SEBAGAI MEDIA PROMOSI DAN PENJUALAN BAGI HOTEL MELATI DI UBUD
Authors: Indrayana Tirtayasa Pande Putu , Paturusi Syamsul Alam 
Published: October 2017

The growth of the number of hotel rooms in Ubud has caused
increasing business competition among the so called non-star
melati hotel.Non-star melati hotel is a category of hotel which is
not qualified to be awarded as a star hotel by Indonesian Ministry
of Tourism.In response to the competition, the hotels embrace
internet as a sales and promotion media by developing hotel
websites.Individual tourism trend ignites the emergence of online
travel agency websites (OTA) which used by tourists to compare
and choose hotels thus increasing the importance of internet as a
channel for selling and promoting hotel products.The purposes
of this research are to identify motivation, perception, advantages and disadvantages of hotel website and OTA by non-star melati hotel operator’s perspective.Theories used are motivation, perception, and SWOT theory. Data was analyzed with descriptive qualitative method.Results show that hotel website and OTA have its own advantages and disadvantages. Motivation in using hotel website and OTA are very high.Perception in using hotel website and OTA are very agree. It is advised that hotels need to focus more on using OTA as source of getting guests, but also using hotel website, together as medium for promotion and sales activities.
IKON HABIBIE-AINUN, STRATEGI INOVATIF DALAM MENGEMBANGKAN PARIWISATA DI KOTA PAREPARE, SULAWESI SELATAN
Authors: Junaid Ilham , Hanafi Hamsu 
Published: October 2017

Empirical data on how the local governments implement tourism
innovation is very limited. Thus, it is necessary to explore how the regional board of tourism develops tourism potential through innovative approach.The aims of this research are to explore the festival of Habibie-Ainun as well as to recommend ways in optimizing the festival for community welfare.This research is a qualitative study by interviewing (in-depth interview) four staff at the regional board of tourism as well as doing participant observation at Parepare city.The research reveals that Habibie-Ainun is choosen as an icon of tourism because of the enchantment of Habibie, the former president of Indonesia who was born in Parepare city.Habibie-Ainun festival, becak of tourism and the statue of Habibie-Ainun are considered as innovative strategies in attracting tourists.This research suggests that strategy of Habibie-Ainun should be supported with various and continuous activities that may involve tourists particularly in the area of the statue.The local government should also inform the community on how the strategy can help community improve their income through tourism. Innovative strategies may come from the community, and thus, it is important to strengthen synergy between the local government and the community.
PENGEMBANGAN AGROWISATA UNTUK KEMANDIRIAN EKONOMI DAN PELESTARIAN BUDAYA DI DESA KERTA, PAYANGAN GIANYAR
Authors: Gunawan I Made 
Published: October 2017

Kerta Village, Payangan, Gianyar regency, Bali, has a large and
diverse potential to develop as agrotourism.However, these natural and cultural potentials have not been optimally managed.This study aims to determine the potential of villages that can be developed as agrotourism products, knowing the internal and external factors that influence of agrotourism development, formulating strategy and program to develop it.This study uses qualitative methods, data collection is done through observation, questionnaires, and in-depth interviews on elements of the society, the government and tourism entrepreneurs. Qualitative descriptive analysis was performed by applying the theory of tourism area life cycle, systems theory, and planning theory.The results showed that the village potential that has been depeloping and it can be developed further as agrotourism products, grouped into four categories, namely of nature potential, agriculture, cultural, and attractions.From the view of tourism are life cycle,Kerta Village Agrotourism are in the involvement phase marked by the growing involment of community to tourism activities.
STRATEGI PENGEMBANGAN WILAYAH PERBATASAN NUSA TABUKAN KABUPATEN KEPULAUAN SANGIHE BERBASIS EKOWISATA BAHARI
Authors: Lesawengen Juita Carolina 
Published: October 2017

Nusa Tabukan in Sangihe Islands Regency is a cluster of small
islands at the outer teritorry, consist of four islands that located
in the northern part on Sangihe Island.The aims of this research
were to identify potential tourist attractions, analyzing internal
and external factors, and formulating proper marine ecotourism
strategies and programs.The results indicate that potentials attractions can be developed at Nusa Tabukan. Those are the nature and socio-culture environment.Small islands, white sandy beaches, coral reefs, mangrove forest, sea grass, dugong¸local wisdom as well as economic activities on community can be developed as marine tourism attractions.However, there were some obstacles related to tourism development such as human resources, tourism facilities and infrastructure and accessibility.This research formulated the grand strategy S-O to be applied which is strategy of marine ecotourism development in border cross area, while alternative strategies are also formulated.Roles of relates stakeholder is necessary needed to ensure the development is on the right track of sustainability.
PENGEMBANGAN FITRAH MANUSIA MELALUI KONSELING ISLAM
Authors: Siregar Risdawati 
Published: October 2017

Abstrak: Fitrah is basic ability of growth and development of human who has born. There is fitrah in humans’s body who has not growth and get function, so Allah closes their hearth until they can not see the truth, then they misguided and do not want to accept Allah’s direction. But there is fitrah can grouth and get function, Allah gives every body physical, spiritual and nafs, therefore Allah keeps hearth and greeting full of faith and makes them as human kaffah, then they can give benefit to their environment. So, the role of guidance and Islam counseling services help everybody to develop human’s fitrah, empowering faith, mind and desire for learning the demand of Allah and His Messenger.Keywords: Abstrak: Fitrah adalah kemampuan dasar dari pertumbuhan dan perkembangan manusia yang telah lahir. Terdapat fitrah dalam tubuh manusia yang belum tumbuh dan berfungsi, sehingga Allah menutup kediaman mereka sampai mereka tidak bisa melihat kebenaran, maka mereka sesat dan tidak mau menerima arahan Allah. Tapi ada fitrah bisa tumbuh dan berfungsi, Allah memberikan setiap tubuh fisik, spiritual dan nafsu, karena itu Allah membuat kediaman dan salam penuh iman dan membuat mereka sebagai manusia kaffah, maka mereka dapat memberikan manfaat bagi lingkungan mereka. Jadi, peran bimbingan dan Islam layanan konseling membantu semua orang untuk mengembangkan fitrah manusia, pemberdayaan iman, pikiran dan keinginan untuk belajar kebutuhan dari Allah dan Rasul-Nya.Kata Kunci: Fitrah and Counseling