bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harnessing the Power of Emerging Digital Technologies for improved Sustainability and Productivity in Biomedical Engineering and Neuroscience
Authors: Sheikhbahei Erfan , AKILLI ARI Aysu 
Published: September 2024

This article discusses the potential of using digital technologies like blockchain, AI, IoT and big data analytics to improve resource efficiency, supply chain management, decision making and reduce fraud. It highlights how blockchain can create a transparent and tamper-proof system for tracking forest products from harvest to sale, reducing fraud and improving sustainability. The implementation of blockchain is argued to lead to substantial improvements in supply chain management through increased transparency and traceability. Moreover, AI, blockchain, IoT and advanced analytics are said to help optimize production and supply chains, detect fraud early, and improve forecasting and risk management for more efficient policies. The adoption of technologies like IoT, smart sensors and standardized data protocols is also outlined as a way to revolutionize sectors like agriculture, manufacturing and energy through enhanced productivity and efficiency. Emerging digital technologies like artificial intelligence, bioengineering, internet of things, data analytics and digital transformation offer immense potential to address global challenges and drive progress. Artificial intelligence and machine learning algorithms can be applied to improve healthcare, education, transportation and resource management by processing large datasets. When combined with IoT, these technologies enable precision agriculture, predictive maintenance, and smart infrastructure for sustainable development. Advancements in bioengineering such as synthetic biology, biomimicry and biomanufacturing aim to solve problems in medicine, energy and environment by emulating nature. IoT connects physical objects through sensors and networks to collect and exchange data, allowing devices, vehicles and systems to become intelligent and autonomous. Analytics on these Big Data sets from connected products, facilities and natural systems help reveal valuable insights for evidence-based decision making. Digital transformation of industries and business models leverages these technologies to enhance productivity, efficiency and consumer experiences through virtual and augmented realities, cloud computing and automated processes. However, responsible innovation through interdisciplinary research and governance is required to ensure such progress addresses societal needs, reduces inequalities and minimizes environmental impacts. Cross-sector collaborations involving industry, academia and policymakers can help maximize benefits while preemptively mitigating potential risks.
Penentuan Keputusan Pemilihan Kartu Provider Menggunakan Metode Analytical Hierarchy Process
Authors: Zistiani Sylvi 
Published: September 2024

Banyaknya persaingan antara kartu provider yang menawarkan paket internet membuat mahasiswa Universitas Bina Sarana Informatika (UBSI) kebingungan dalam memilih kartu provider yang cocok untuk mendukung aktivitas online mereka. Oleh karena itu, penelitian ini bertujuan untuk mengetahui kriteria dan alternatif yang dipertimbangkan oleh mahasiswa dalam memilih kartu provider. Penelitian ini dilakukan dengan menggunakan studi kasus terhadap mahasiswa UBSI yang tinggal di Jakarta, dengan jumlah sampel sebanyak 87 mahasiswa. Responden diminta untuk mengisi kuesioner yang membandingkan tingkat kepentingan antara kriteria dan alternatif. Data dari kuesioner kemudian dianalisis menggunakan metode Analytical Hierarchy Process (AHP) menggunakan Microsoft Exel dan software Expert Choice. Hasil analisis AHP menunjukkan bahwa kriteria kualitas jaringan merupakan kriteria yang paling dipertimbangkan oleh mahasiswa dalam memilih kartu provider, diikuti oleh kriteria kuota, harga, bonus, dan kemudahan penggunaan. Telkomsel terbukti menjadi operator seluler penyedia layanan internet yang paling diminati oleh mahasiswa, karena memiliki bobot tertinggi yaitu 0,420. Alternatif kartu provider selanjutnya yang dipilih secara berurutan adalah XL Axiata dengan bobot 0,329 dan IM3 dengan bobot 0,250.

Students at Bina Sarana Informatika University (UBSI) struggle to select the best provider card to support their online activities because there is so much rivalry among provider cards that offer internet packages. Therefore, the purpose of this study is to identify the factors and options that students take into account when selecting a card provider. The Analytical Hierarchy Process (AHP) method was used to evaluate the survey data using Microsoft Exel and Expert Choice software. According to the findings of the AHP analysis, students prioritize network quality over other factors like price, bonus, quota, and simplicity of use when selecting a card provider. Because it has the greatest weight (0.420), Telkomsel has demonstrated that it is a mobile operator offering internet services that students are most interested in. XL Axiata and IM3 are the next two alternate provider cards chosen in order of weight, each with a weight of 0,329 and 0.250.
Management of vicharchika (eczema) - An ayurvedic approach
Authors: Mucherla Srikanth , Mohan G. Vinay , Dharmannavar Girish Kumar S 
Published: September 2024

Vicharchika is one among the disorders that has increased due to the globalization and has incapacitated many people due to its impact on their lifestyle. Patients with Vicharchika in general undergo many kinds of treatment but still look out for the treatments that would provide them a permanent relief and would not have a recurrence. Ayurveda assures the relief with more focus on prevention. In Ayurveda, Vicharchika is understood as one among the Kustha or the skin disorders and Eczema in Modern medicine. This condition is managed with oral and local medications as per the Modern medicine and a comprehensive treatment including Shodhana and Shamana chikitsa with Sthanika chikitsa with appropriate pathya aahara and pathya vihara according to Ayurveda that serves the objective of the Ayurvedic science that the prevention is better than cure.The present study is an attempt to review the management of Vicharchika both from the Modern and the Ayurvedic perspectives.
Keywords: Vicharchika, Eczema, Ayurveda, Atopic Dermatitis
Ethnomedicinal aspect of Bharangi (Clerodendrum Serratum Linn Moon)
Authors: Babubhai Sangada Viral , Singh Suman , Jani Dilip 
Published: September 2024

Background: Ethnomedicine generally refers to the study of traditional medicine practiced by different ethnic groups for the prevention and treatment of diseases. Bharangi (Clerodendrum serratum (Linn) Moon) is a perennial shrub belongs to the Verbenaceae family. Traditionally, Bharangi is used as a medicine for various ailments in India. Material & Method: Available books on ethnomedicine and various online articles and websites were referred to collect information about Bharangi. Collected data were presented systematically and in tabular form. Observation & Result: Referring various books, articles in detail adds up a vast therapeutics range of Bharangi. Discussion: Bharangi has wide range of therapeutic application such as in Asthma, epilepsy, snake bite, mouth ulcer, alopecia, hair loss, etc. But it has remained clinically very less explored. Conclusion: Present review study, inferred that more such tribes can be explored for its various uses which can be beneficial to other people once it is scientifically proven.
An Investigation of Molecular Property Prediction and Classification Based on Machine Learning Algorithms
Authors: Chen Yanzi 
Published: September 2024

With the rapid advancement of science and technology, chemical and physical research has entered an era of complexity and high dimensionality, where traditional research paradigms struggle to optimize vast chemical parameter searches. The Machine Chemist platform was developed in this context, leveraging big data and intelligent models to automate chemical synthesis, characterization, and testing processes. This study aims to predict the y1, y2 and y3 properties and classes of 2,580 molecules based on their physicochemical properties and improve model accuracy through data analysis and modeling. Data preprocessing involved removing missing values, duplicates, and outliers using the quartile method, resulting in an analyzable dataset. A scatter plot of y2 and id suggested a univariate polynomial function relationship, leading to the construction of a univariate nonlinear regression model. The model achieved a high prediction accuracy, with a low root mean square error and a high coefficient of determination. Additionally, the relationship between class and y1~y3 , x1~x100 indicators was examined, revealing mostly nonlinear relationships. A random forest model was established to classify 2,580 molecules into 1 to 4 classes based on the properties of 200,000 chemical molecules. The model's performance was evaluated using decision trees, confusion matrices, precision, and recall metrics. Finally, the SHAP method assessed the impact of feature indicators on classification outcomes, contributing to the development of a reliable molecular category prediction model.
Optimasi Konsentrasi Avicel PH 102 dan Natrium karboksimetilselulosa (NaCMC) dengan Desain Faktorial Lengkap Pada Formulasi Tablet Ekstrak Etanol Daun Kencana Ungu (Ruelia tuberosa L.)
Authors: Stiani Sofi Nurmay , Anjani Shabrina Talitha , Marlina Nia , Yusransyah Yusransyah 
Published: September 2024

Tumbuhan kencana ungu (Ruellia tuberosa L.) merupakan tanaman liar atau lebih dikenal sebagai gulma yang tumbuh subur di Pulau Jawa. Kandungan flavonoid yang terdapat dalam ekstrak etanol 96% daun kencana ungu berfungsi sebagai zat antioksidan yang berperan dalam menetralisir radikal bebas dan menghambat reaksi peroksidasi lipid. Tablet ekstrat etanol 96% daun kencana ungu dkombinasikan dengan Na-CMC dan avicel PH 102 dibuat beberapa konsentrasi. Penggunaan Na CMC sebagai pengikat karena karena memiliki daya rekat yang kuat, meningkatkan kekerasan tablet, bersifat non toksik, dan non iritan, mudah diperoleh serta relatif murah dan avicel PH102 sebagai bahan penghancur yang menunjukkan sifat alir serta kompaktibilitas yang baik. Tujuan penelitian ini adalah untuk mengetahui pengaruh kombinasi bahan eksipien terhadap sifat fisik tablet serta mendapatkan formula yang optimum kombinasi Na-CMC dan avicel PH 102 pada tablet menggunakan metode faktorial lengkap. Ekstraksi daun kencana ungu dilakukan dengan metode maserasi menggunakan etanol 96%. Granulasi basah dilakukan dengan perbandingan konsentrasi Na-CMC dan avicel PH 102 adalah formula F1 (2,8:14) mg; formula FA (16,8:14) mg; formula FB (2,8:42) mg; dan formula FAB (16,8:42) mg. Metode optimasi yang digunakan adalah factorial design dengan menginput data hasil uji sifat fisik granul maupun tablet. Hasil evaluasi sudut diamdari granul, keseragaman bobot tablet, dan kerapuhan tidak berpengaruh signifikan terhadap semua variabel sampel. Response optimization nilai desirability yang dihasilkan dari metode optimasi factorial design yaitu 0,6492 dengan menunjukkan formula optimum dengan bobot Na-CMC 2,8 mg dan avicel PH 102 14 mg.
Literature Review Analisis Utilitas Biaya Terapi Adjuvan pada Pasien Kanker Payudara HER-2 Positif
Authors: Udin Baha , Yusransyah Yusransyah , Anita Nugraheni Diesty 
Published: September 2024

Kanker payudara merupakan salah satu penyakit penyebab kematian wanita di dunia. Tingginya biaya yang dikeluarkan untuk pengendalian penyakit kanker dapat berpengaruh terhadap pengendalian penyakit yang lain. Salah satu terapi yang diberikan kepada pasien kanker payudara, yaitu terapi adjuvant. Review artikel ini bertujuan untuk mengetahui utilitas biaya terapi adjuvant pada pasien kanker payudara Human Epidermal Growth Factor Receptor-2 (HER-2) Positif di berbagai negara. Metode review artikel yang digunakan yaitu literature review dengan melakukan studi kepustakaan melalui data base Pubmed dan Google Scholar. Setelah melakukan studi pustaka, didapatkan 37 artikel namun hanya 4 artikel yang memenuhi kriteria inklusi dan eksklusi. Artikel yang digunakan merupakan artikel-artikel yang memebahas terkait perbandingan efektivitas biaya dengan kualitas hidup sebagai outcome klinis dari terapi adjuvan yang digunakan oleh pasien kanker payudara HER-2 Positif. Artikel yang digunakan dilakukan di 4 negara, yaitu Amerika Serikat, Jepang, Filipina, dan Brazil. Hasil review pada setiap artikel yang digunakan menunjukkan masing-masing negara memiliki perbedaan strategi dengan biayanya dalam melakukan pemberian terapi adjuvant kepada pasien kanker payudara HER-2 Positif. Penggunaan terapi adjuvan dengan total biaya paling tinggi, yaitu trastuzumab emtansine (T-DM1) di Amerika Serikat (USD 218.179,98). Nilai ICER paling tinggi pada review artikel ini, yaitu perbandingan trastuzumab tunggal dengan kombinasi trastuzumab-neratinib (USD 416.106) di Amerika Serikat. Terapi yang menghasilkan nilai outome klinis kualitas hidup paling tinggi, yaitu T-DM1 (17,310) di Brajil dan Amerika Serikat. Terdapat perbandingan total biaya dan efektivitas terapi adjuvant kanker payudara HER-2 positif. Perbedaan total biaya dan efektivitas biaya dipengaruhi oleh waktu penelitian, populasi, kebijakan terkait penentuan minimal biaya pengobatan, mata uang, dan metode penelitian
Hubungan Tingkat Pengetahuan Dan Sikap Masyarakat Tentang Dagusibu Obat Di Desa Lebakwangi Kecamatan Arjasari Kabupaten Bandung
Authors: Roni Asep , Sri Mas Hartini Ni Nyoman , Dista Asmarani R. Mayang 
Published: September 2024

DAGUSIBU merupakan salah satu upaya peningkatan kesehatan bagi masyarakat yang diselenggarakan melalui kegiatan pelayanan kesehatan oleh tenaga kefarmasian. DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) adalah Program Gerakan Keluarga Sadar Obat yang diprakarsai oleh Ikatan Apoteker Indonesia dalam mencapai pemahaman dan kesadaran masyarakat terhadap penggunaan obat dengan benar. Berdasarkan hasil riset Kesehatan Dasar Riskesdas tahun 2013 menunjukan bahwa 35,2% rumah tangga menyimpan obat untuk swamedikasi. Merujuk dari 35,2% rumah tangga yang menyimpan obat, 35,7% diantaranya menyimpan obat keras, dan 27,8% di antaranya menyimpan antibiotik dan 86,1% antibiotik tersebut diperoleh tanpa resep. Tujuan dari penelitian ini adalah untuk mengetahui sejauh mana masyarakat umum di Desa Lebakwangi yang terletak di Kecamatan Arjasari Kabupaten Bandung mengetahui tentang Dagusibu obat. Metode yang digunakan dalam penelitian ini adalah deskriptif kuantitatif menggunakan desain One Group Pretest and Posttest dengan pendekatan accidental sampling. Hasil penelitian menunjukkan memiliki tingkat pengetahuan pada kategori baik tentang DAGUSIBU Obat mengalami peningkatan sebanyak 27%, dan memiliki tingkat sikap terhadap DAGUSIBU Obat pada kategori baik mengalami peningkatan sebanyak 16%. Tingkat pengetahuan masyarakat berhubungan dengan sikap. Berdasarkan hasil uji kolerasi spearman menunjukkan nilai p value sebesar 0.048.
PENGELOLAAN BUM DESA DALAM MENYEJAHTERAKAN EKONOMI MASYARAKAT MELALUI SISTEM EKONOMI ISLAM
Authors: M. ilham zainullah  , Jazilah Sukron 
Published: September 2024

Penelitian ini dilatarbelakangi oleh BUM Desa sebagai lembaga kewirausahaan yang bertujuan menstimulus dan menggerakkan perekonomian di desa. Oleh karenanya BUM Desa diharapkan mampu memotong kesenjangan ekonomi baik yang ada di ruang lingkup desa maupun antar desa-kota.Tujuan penelitian ini untuk mengetahui pola penglolaan, bentuk usaha, dampak, dan factor-faktor yang mempengaruhi pengelolaan BUM Desa Permata dalam menyejahterakan ekonomi masyrakat melalui Sistem Ekonomi Islam. Penulisan penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan deskriptif.Hasil penelitian yang diperoleh penulis dapat disimpulkan bahwa (1) pengelolaan BUM Desa dalam menyejahterkan ekonomi masyarakat melalui sistem ekonomi Islam meliputi perencanaan, pengorganisasian, pelaksanaan, pengawasan, dan pengevaluasian; (2)Bentuk usaha berbasis Ekonomi Islam yang dilaksanakanoleh BUM Desa Permata dalam menyejahterakan ekonomi masyarakat desa Suco ialah pemberdayaan, syirkah, bai’, danijarah; (3) Dampak pengelolaan BUM Desa Permata dalam menyejahterakan ekonomi masyarakat desa Suco melalui Sistem Ekonomi Islam masih belum memuasakan karena unit usaha yang dijalankan tidak akurat, yang mana mayoritas penduduk desa Suco berprofesi sebagai petani dan pekebun; (4) Faktor-Faktor yang menjadi penghambat dan pendukung dalam pengelolaan BUM Desa Permata untuk menyejahterakan ekonomi masyarakat desa Suco melalui Sistem Ekonomi Islam ialah: (factor penghambat) berupa rendahnya mutu Sumber Daya Manusia (SDM), pemilihan unit usaha, dan minimnya partisipasi masyarakat; (faktor pendukung) berbentuk support dari pemerintah desa.
Effect of Organic Manure on Growth, Yield and Quality of Strawberry (Fragaria × ananassa Duch.) under Prayagraj Climatic Condition in Shade Net House
Authors: Bora Anshuman Singh , Singh Devi , Tayde Anoorag R. 
Published: September 2024

The present study entitled “Effect of organic manure on growth, yield and quality of strawberry (Fragaria × ananassa Duch.) under prayagraj climatic condition in shade net house” was carried out at the experiment field of the department of horticulture, Allahabad school of agriculture, SHUATS, Prayagraj during the year 2023-2024. Organic manures treatments include T0 Control T1 FYM (12t/ha.) T2 Poultry Manure (8t/ha.) T3 Vermi-compost (10t/ha.) T4 Coco-peat (1t/ha.) T5 50% FYM +50% Poultry Manure (6t/ha+4t/ha) T6 50% FYM + 50% Vermi-compost (6t/ha + 5t/ha.) T7 50% Poultry Manure + Vermi-compost (4t/ha+5t/ha) T8 25% FYM+ 25% Poultry Manure + 25% Coco-peat+ 25% Vermi-compost (3t/ha. + 2t/ha. + 0.25t/ha+ 2.5t/ha.) The effect of Organic Manure on growth and yield of Strawberry recorded maximum plant height, plant spread and number of leaves in T8 18.89 DAT, 23.78 DAT, 18.12 DAT respectively. Floral characters significantly took minimum days. The maximum fruit weight 25.31gram were recorded in T8 with highest yield 331.32 g/plant. Quality parameters includes maximum T.S.S (8.16) 0Brix along with minimum acidity percentage (0.55%). On the basis of our experimental findings it was concluded that the treatment T8: 25% FYM + 25% Poultry Manure + 25% Coco-peat + 25% Vermi-compost (3t/ha. + 2t/ha. + 0.25t/ha. + 2.5t/ha.) was found to be best in the terms of vegetative parameters, phenological parameters, flowering and fruiting parameters, yield and quality parameters. The benefit cost ratio was highest in the same treatment with (3.50).
Role of Cattle Egrets in the Dissemination of Multi-drug Resistant Escherichia coli: A One Health Perspective
Authors: Joshi Pushpit , Joshi Namita , Joshi Rajesh Kumar , Dwivedi Pragya 
Published: September 2024

This study was carried out to establish the role of cattle egrets that feed on a nearby animal farm as a possible source of MDR bacteria. A total of 50 faecal dropping samples of cattle egret were collected from cattle farm and processed in the laboratory for isolation of E. coli. Total 45 isolates were recovered, of which 20 were identified and characterized as E. coli morphologically and biochemically. The antibiogram profile of all E. coli isolates recovered from cattle egret revealed 100% resistance to Ampicillin, Cloxacillin and Cefotaxime. Antibiotics such as Imipenem, Gentamycin, Trimethoprim, and Triple sulphas were found highly sensitive (100%) followed by Streptomycin (90%). The Sensitivity of Norfloxacin and Kanamycin ranged between intermediate to high degree, while Polymyxin was found sensitive for 55% isolates. Multi antimicrobial resistance index of all the isolates was found to be more than 0.27 indicating a “high risk” for the community. These, MDR positive E. coli, were further subjected to phenotypic and genotypic confirmation of ESBL producers by DDST and PCR, respectively. Out of 20, 12 isolates (60%) were confirmed as ESBL producers by DDST and PCR. PCR analysis of ESBL positive isolates revealed the predominance of bla CTX gene. All E. coli were also evaluated for pathogenicity using in vitro tests and 50% and 40% of the isolates were found to be pathogenic on the Congo red binding and hemolysis test, respectively. In the present study, the occurrence of MDR E. coli and ESBL producers in cattle egret is a cause of concern for public health and animal health.
Sociological and Economical Impact of Grapes Growers in Dindigul District, Tamil Nadu, India
Authors: Priyanka R. 
Published: September 2024

The research examined the economic and social consequences of grape growers on one block in the Dindigul district of Tamil Nadu, involving three villages that were purposefully chosen and 120 respondents who were chosen at random. It was discovered that the participant primary source of income for subsistence was grape cultivation. A planned schedule was used to gather data in order to quantify the socioeconomic status of grape growers. According to the data, the majority (53.33%) of respondents belonged to the middle age category followed by 34.16 per cent of the respondents had the education was up to higher secondary and 30.83 per cent had middle school level. Majority (52.50 per cent) of the respondents had medium level of annual income, followed by majority of the respondents had agriculture as their main occupation for their livelihood. Majority of the farmers, or 90.83 percent, had nuclear families with fewer than five members and only 09.16 percent of those surveyed had a large family. Maximum number of respondents (82.50 per cent) had pointed out the independent decision followed by remaining 17.50 per cent of the respondents had pointed the joint decision. Majority (55.83 per cent) of the respondents belonged to small farmer category Majority of the respondents had medium level of mass media exposure and extension agency contact. Here it concluded that the overall socioeconomic condition was found be to medium range among the grape growers. The Government of Tamil Nadu's Department of Horticulture must work hard to inform grape growers about better grape varieties and cultivation practices to improve the socio-economic status.