bluuebunny/crossref_metadata_2025_split huggingface dataset:
Floral biology and breeding behaviour of Melia azedarach L.: imperative for hybridization
Authors: Mohapatra Sourav Ranjan , Das Susanta Kumar , Kar Manas Ranjan , Das Harekrishna 
Published: September 2024

AbstractMelia azedarach L. commonly called Maha Neem is an economically and industrially important tree species with global significance. Although species possess versatile importance worldwide, information on reproductive biology and breeding system is scarce and limited for eastern coastal plain of India. Therefore, current study provides a detailed report on reproductive biology of M. azedarach. Maha Neem was found to bear violet to whitish violet, slightly fragrant, 14.99 ± 0.05 mm. long and 17.01 ± 0.08 mm. wide flowers. This tree commenced opening of floral buds during March and continued until May with a peak during March-end. The anthesis of species peaked between 08:00 and 10:00 am, which coincides with insect activity. Anthers were observed to dehisce during or shortly before anthesis; however, stigma started receptivity before anthesis and continued invitation up to 12 h after anthesis. Pollen viability ranged from 96.67 ± 1.6% to 98.26 ± 1.2 at the time of anthesis; after that decreased rapidly. Pollen: ovule ratio of 1096.38 ± 108.70 indicated the possibility of autogamy. The breeding system of M. azedarach revealed that fruit sets under natural pollination (NP) were significantly higher than Xenogamy. However, substantial difference was not reported in fruit set percentage under natural pollination and Autogamy, which is strong evidence in favour of self-pollination. Moreover, Maha-Neem is entomophilous with frequent visits by Apis and Syrphid flies. Current findings will be helpful in designing potent conservation strategies and planning successful breeding programmes.
Fatty acids profile in pregnancies affected by neural tube defects
Authors: Nasri Kaouther , Fenina Hana , Kloula Ben Ghorbal Salma , Maamer Dhouha , Ben Jamaa Nadia , Feki Moncef , Siala Gaigi Soumeya 
Published: September 2024

Abstract
This study aimed to determine if maternal fatty acids (FA) levels during pregnancy are associated with the occurrence of neural tube defects (NTDs) and to explore the correlation between FA and maternal vitamin D, homocysteine, vitamin B12, and folate in cases. Plasma FA composition was assessed using capillary gas chromatography. Comparisons between cases and controls were performed by independent samples t-test for continuous variables. Cases had significantly higher levels of heptadecanoic acid, linolelaidic acid, and arachidonic acid (ARA):(eicosapentaenoic acid+docosahexaenoic acid) ratio than controls (p < 0.05). Nervonic acid, ARA, adrenic acid, eicosapentaenoic acid, docosahexaenoic acid, and omega-3 polyunsaturated fatty acids (n-3 PUFA) levels were significantly lower in cases (p < 0.05). Maternal 25-hydroxyvitamin D (25(OH)D) levels were positively correlated with maternal polyunsaturated fatty acids and omega-6 polyunsaturated fatty acids. RBC folate levels were negatively correlated with n-3 PUFA.
Further research is required to clarify the association of FA metabolism with NTDs.
Let’s talk about recovery in mental health: an international Delphi study of experts by experience
Authors: Guerrero E. , Barrios M. , Sampietro H. M. , Aza A. , Gómez-Benito J. , Guilera G. 
Published: September 2024

Abstract

Aims
The concept of recovery is featured in the strategic plans of the World Health Organization as well as in other national mental health plans; however, there have been differing interpretations of what it means. This article aims to achieve a consensus on the key aspects of recovery in mental health from the perspective of movements of users and survivors of psychiatry at an international level. Four specific objectives were proposed in this study: (1) to identify what recovery in mental health means, (2) to identify the indicators that a person is progressing in their recovery, (3) to determine the factors that facilitate the recovery process, and (4) to determine the factors that hinder the recovery process.

Methods
A three-round e-Delphi study was conducted with the participation of 101 users and survivors of psychiatry, adhering to the CREDES checklist to ensure methodological rigour.

Results
The results reveal 26 key aspects that define recovery, 31 indicating that a person is progressing in their recovery process, 8 that facilitate recovery and 12 that hinder recovery. The most agreed-upon statements for defining recovery highlight the importance of empowerment, leading a fulfilling life, ensuring safe-living conditions and acknowledging individuals as holders of rights. Similarly, empowerment and agency were highly agreed upon as relevant recovery indicators. Key findings underscore the significance of a supportive and respectful social environment in facilitating recovery, while coercion, discrimination and lack of support from significant others hinder recovery.

Conclusions
Despite cultural differences and recovery’s subjective nature, our results demonstrate that an international consensus on critical recovery aspects is attainable. Highlighting a significant shift, we emphasize the ‘Transition’ process to signify moving away from the biomedical model approach and advocating for collective rights. Our findings advocate for empowerment, users’ rights and the move towards person-centred care that integrates social, political and economic contexts. These consensus statements lay the groundwork for future research across diverse regions and cultures, offering insights into recovery’s meaning and potential for innovative approaches in diagnosis, intervention and evaluation.
Sustainability scientists’ critique of neoclassical economics
Authors: Diesendorf Mark , Davies Geoff , Wiedmann Thomas , Spangenberg Joachim H. , Hail Steven 
Published: September 2024

Abstract

Non-technical summary
Neoclassical economics (NCE) theory and neoliberal economics practice together form one of the principal driving forces of environmental destruction and social injustice. We critically examine ten key hypotheses that form the foundations of NCE, and four other claims. Each fails to satisfy one or more of the basic requirements of scientific practice. Hence, NCE is fundamentally flawed, is irrational in the common meaning of the word, and should not be used as a guide for government policies. Because NCE is socially constructed, it can be replaced with an interdisciplinary conceptual framework that is compatible with ecological sustainability and social justice.

Technical summary
Neoclassical economics (NCE) is widely regarded as providing theoretical justification for neoliberal notions such as ‘governments should minimize regulation and spending, and hence leave major socioeconomic and environmental decisions to the market’. A large body of literature finds that NCE is largely responsible for environmental destruction and social inequality. As NCE is claimed to be a science and has appropriated terminology (without the content) from physics, we examine critically its basic hypotheses and four other claims from a viewpoint of natural scientists and an ecological economist, each a sustainability researcher. This paper defines NCE in two ways: as a theoretical structure for economics based on (1) the hypotheses of methodological individualism, methodological instrumentalism and methodological equilibration, and (2) the three hypotheses named above together with seven other common hypotheses of NCE. We find that each hypothesis and claim fails to satisfy one or more basic requirements of scientific practice such as empirical confirmation, underlying credible or empirical assumptions, consistency with Earth system science, and internal consistency. Sensitivity analysis is rare and ability to predict is lacking. Therefore, we recommend that neoclassical microeconomics be reformed and neoclassical macroeconomics be abandoned and replaced with a transdisciplinary field such as social ecological economics.

Social media summary
Conventional economics, a driver of environmental damage and social inequality, fails examination by sustainability scientists.
Mars Soil Temperature and Thermal Properties From InSight HP3 ${\mathrm{H}\mathrm{P}}^{3}$ Data
Authors: Spohn T. , Müller N. , Knollenberg J. , Grott M. , Golombek M. P. , Plesa A.‐C. , Bickel V. T. , Morgan P. , Krause C. , Breuer D. , Smrekar S. E. , Banerdt W. B. 
Published: September 2024

AbstractDiurnal and seasonal variations in soil and surface temperature measured with the thermal probe and radiometer of NASA's InSight Mars mission are reported. At a representative depth of 10–20 cm, an average temperature of 217.5 K was found, varying by 5.3–6.7 K during a sol and by 13.3 K during the seasons. From the damping of the temperature variation with depth and the phase shift, a thermal diffusivity of (3.93 0.39) × /s was derived for the upper 10 cm from the diurnal temperature variation and of (3.63 0.53) × /s for the 40 cm depth range of the mole from the annual temperature variation. Using published thermal conductivity and inertia values together with the diffusivities, soil densities of 1,470 and 1,730 kg/ were derived for these depths. The temperatures allow the deliquescence of thin films of brine, the efflorescence of which may explain the cemented duricrust observed.
Seismic Modeling of Bedload Transport in a Gravel‐Bed Alluvial Channel
Authors: Luong Loc , Cadol Daniel , Bilek Susan , McLaughlin J. Mitchell , Laronne Jonathan B. , Turowski Jens M. 
Published: September 2024

AbstractRecent theoretical models and field observations suggest that fluvial bedload flux can be estimated from seismic energy measured within appropriate frequency bands. We present an application of the Tsai et al. (2012, https://doi.org/10.1029/2011gl050255) bedload seismic model to an ephemeral channel located in the semi‐arid southwestern US and incorporate modifications to better estimate bedload flux in this environment. To test the model, we collected streambank seismic signals and directly measured bedload flux during four flash‐floods. Bedload predictions calculated by inversion from the Tsai model underestimated bedload flux observations by one‐to‐two orders of magnitude at low stages. However, model predictions were better for moderate flow depths (>50 cm), where saltation is expected to dominate bedload transport. We explored three differences between the model assumptions and our field conditions: (a) rolling and sliding particles have different impact frequencies than saltating particles; (b) the velocity and angle of impact of rolling particles onto the riverbed differ; and (c) the fine‐grained alluvial character of this and similar riverbeds leads to inelastic impacts, as opposed to the originally conceptualized elastic impacts onto rigid bedrock. We modified the original model to assume inelastic bed impacts and to incorporate rolling and sliding by adjusting the statistical distributions of bedload impact frequency, velocity, and angle. Our modified “multiple‐transport‐mode bedload seismic model” decreased error relative to observations to less than one order of magnitude across all measured flow conditions. Further investigations in other environmental settings are required to demonstrate the robustness and general applicability of the model.
Association of metabolic obesity phenotypes with risk of overall and site-specific cancers: a systematic review and meta-analysis of cohort studies
Authors: Mahamat-saleh Yahya , Aune Dagfinn , Freisling Heinz , Hardikar Sheetal , Jaafar Rola , Rinaldi Sabina , Gunter Marc J. , Dossus Laure 
Published: September 2024

Abstract
Background
Adiposity is a known risk factor for certain cancers; however, it is not clear whether the risk of cancer differs between individuals with high adiposity but different metabolic health status. The aim of this systematic literature review and meta-analysis of cohort studies was to evaluate associations between metabolic obesity phenotypes and overall and site-specific cancer risk.

Methods
PubMed and Embase databases were used to identify relevant cohort studies up to the 6th of June 2023. Random-effects models were used to estimate summary relative risks (SRRs) and 95% confidence intervals (CIs) for the association between metabolic obesity phenotypes and cancer risk. Certainty of evidence was assessed using the Cochrane methods and the GRADE tool. This study is registered with PROSPERO, number CRD42024549511.

Results
A total of 15,556 records were screened, and 31 publications covering 15 unique cohort studies were included in this analysis. Of these studies, 22 were evaluated as being at low risk of bias and 9 at moderate risk of bias. Compared to metabolically healthy normal-weight individuals (MHNW), metabolically unhealthy overweight/obese (MUOW/OB) individuals had a higher risk of overall (SRR = 1.21, 95% CI = 1.02–1.44, n = 3 studies, high certainty) and obesity-related cancers (SRR = 1.42, 95% CI = 1.15–1.74, n = 3, very low certainty). Specifically, MUOW/OB individuals were at higher risk of cancers of the postmenopausal breast (SRR = 1.32, 95% CI = 1.17–1.48, n = 7, low certainty), colorectum (SRR = 1.24, 95% CI = 1.16–1.31, n = 6, moderate certainty), endometrium (SRR = 2.31, 95% CI = 2.08–2.57, n = 4, high certainty), thyroid (SRR = 1.42, 95% CI = 1.29–1.57, n = 4, moderate certainty), kidney (SRR = 1.71, 95% CI = 1.40–2.10, n = 3, low certainty), pancreas (SRR = 1.35, 95% CI = 1.24–1.47, n = 3, high certainty), liver (SRR = 1.81, 95% CI = 1.36–2.42, n = 2, moderate certainty), gallbladder (SRR = 1.42, 95% CI = 1.17–1.73, n = 2, high certainty), bladder (SRR = 1.36, 95% CI = 1.19–1.56, n = 2, moderate certainty), and stomach (SRR = 1.50, 95% CI = 1.12–2.01, n = 2, high certainty). In addition, we found elevated risks of most of these cancers among individuals classified as MUNW and MHOW/OB phenotypes compared to those with MHNW phenotype. Our stratified analyses according to metabolic obesity phenotypes suggested that the elevated risks of some cancers were stronger in individuals with MUOW/OB versus those with MHOW/OB or MUNW phenotypes.

Conclusion
These findings suggest that both higher adiposity and metabolic dysfunction were independently associated with increased risk of several cancers, with the strongest associations generally observed among those with both metabolic dysfunction and obesity.
Core and accessory genomic traits of Vibrio cholerae O1 drive lineage transmission and disease severity
Authors: Maciel-Guerra Alexandre , Babaarslan Kubra , Baker Michelle , Rahman Aura , Hossain Maqsud , Sadique Abdus , Alam Jahidul , Uzzaman Salim , Ferdous Rahman Sarker Mohammad , Sultana Nasrin , Islam Khan Ashraful , Ara Begum Yasmin , Hassan Afrad Mokibul , Senin Nicola , Hossain Habib Zakir , Shirin Tahmina , Qadri Firdausi , Dottorini Tania 
Published: September 2024

AbstractIn Bangladesh, Vibrio cholerae lineages are undergoing genomic evolution, with increased virulence and spreading ability. However, our understanding of the genomic determinants influencing lineage transmission and disease severity remains incomplete. Here, we developed a computational framework using machine-learning, genome scale metabolic modelling (GSSM) and 3D structural analysis, to identify V. cholerae genomic traits linked to lineage transmission and disease severity. We analysed in-patients isolates from six Bangladeshi regions (2015-2021), and uncovered accessory genes and core SNPs unique to the most recent dominant lineage, with virulence, motility and bacteriophage resistance functions. We also found a strong correlation between V. cholerae genomic traits and disease severity, with some traits overlapping those driving lineage transmission. GSMM and 3D structure analysis unveiled a complex interplay between transcription regulation, protein interaction and stability, and metabolic networks, associated to lifestyle adaptation, intestinal colonization, acid tolerance and symptom severity. Our findings support advancing therapeutics and targeted interventions to mitigate cholera spread.
An analytic, efficient and optimal readout algorithm for compact interferometers based on deep frequency modulation
Authors: Eckhardt Tobias , Gerberding Oliver 
Published: September 2024

AbstractCompact laser interferometers with large dynamic range are one of the core emerging tools to improve low frequency performance in gravitational wave detectors by providing local displacement sensing with sub 1 $$\text {pm Hz}^{-0.5}$$

pm

Hz

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0.5

precision. Strong sinusoidal frequency modulations are used in such laser interferometers to create heterodyne-like photodetector signals from which the phase and other parameters, such as the absolute distance, can be extracted. The nested sinusoidal function in such signals is a challenge for the real-time parameter estimation in low-noise applications. In this article, we present an algorithm to calculate exact signal parameters in a non-iterative way from such interferometric signals. The algorithm makes use of a recurrence relation between Bessel functions to enable a direct extraction of modulation parameters from the signal. Additionally, the algorithm is capable of dealing with high phase dynamics where the Doppler-shift of the signal becomes relevant and can limit the range and precision of the parameter estimation, if not accounted for. Simulations show that the algorithm is computationally efficient, can be well parallelised and the phase estimation is close to optimal precision given by the Cramer–Rao lower bound of the signal parameters.
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts
Authors: Ruiz-Orera Jorge , Miller Duncan C. , Greiner Johannes , Genehr Carolin , Grammatikaki Aliki , Blachut Susanne , Mbebi Jeanne , Patone Giannino , Myronova Anna , Adami Eleonora , Dewani Nikita , Liang Ning , Hummel Oliver , Muecke Michael B. , Hildebrandt Thomas B. , Fritsch Guido , Schrade Lisa , Zimmermann Wolfram H. , Kondova Ivanela , Diecke Sebastian , van Heesch Sebastiaan , Hübner Norbert 
Published: September 2024

AbstractEvolutionary innovations can be driven by changes in the rates of RNA translation and the emergence of new genes and small open reading frames (sORFs). In this study, we characterized the transcriptional and translational landscape of the hearts of four primate and two rodent species through integrative ribosome and transcriptomic profiling, including adult left ventricle tissues and induced pluripotent stem cell-derived cardiomyocyte cell cultures. We show here that the translational efficiencies of subunits of the mitochondrial oxidative phosphorylation chain complexes IV and V evolved rapidly across mammalian evolution. Moreover, we discovered hundreds of species-specific and lineage-specific genomic innovations that emerged during primate evolution in the heart, including 551 genes, 504 sORFs and 76 evolutionarily conserved genes displaying human-specific cardiac-enriched expression. Overall, our work describes the evolutionary processes and mechanisms that have shaped cardiac transcription and translation in recent primate evolution and sheds light on how these can contribute to cardiac development and disease.
A wireless W-band 3D-printed temperature sensor based on a three-dimensional photonic crystal operating beyond 1000 ∘C
Authors: Sánchez-Pastor Jesús , Kadĕra Petr , Sakaki Masoud , Jakoby Rolf , Lacik Jaroslav , Benson Niels , Jiménez-Sáez Alejandro 
Published: September 2024

AbstractIn addressing sensing in harsh and dynamic environments, there are no available millimeter-wave chipless and wireless sensors capable of continuous operation at extremely high temperatures. Here we present a fully dielectric wireless temperature sensor capable of operating beyond 1000 ∘C. The sensor uses high-Q cavities embedded within a three-dimensional photonic crystal resonating at 83.5 GHz and 85.5 GHz, and a flattened Luneburg lens enhances its readout range. The sensor is additively manufactured using Lithography-based Ceramic Manufacturing in Alumina (Al2O3). Despite the clutter, its frequency-coded response remains detectable from outside the furnace at 50 cm and at temperatures up to 1200 ∘C. It is observed that the resonance frequencies shift with temperature. This shift is linked to a change in the dielectric properties of Al2O3, which are estimated up to 1200 ∘C and show good agreement with literature values. The sensor is thus highly suitable for millimeter-wave applications in dynamic, cluttered, and high-temperature environments.
Individual differences in belief updating and phasic arousal are related to psychosis proneness
Authors: Murphy Peter R. , Krkovic Katarina , Monov Gina , Kudlek Natalia , Lincoln Tania , Donner Tobias H. 
Published: September 2024

AbstractMany decisions entail the updating of beliefs about the state of the environment by accumulating noisy sensory evidence. This form of probabilistic reasoning may go awry in psychosis. Computational theory shows that optimal belief updating in environments subject to hidden changes in their state requires a dynamic modulation of the evidence accumulation process. Recent empirical findings implicate transient responses of pupil-linked central arousal systems to individual evidence samples in this modulation. Here, we analyzed behavior and pupil responses during evidence accumulation in a changing environment in a community sample of human participants. We also assessed their subclinical psychotic experiences (psychosis proneness). Participants most prone to psychosis showed overall less flexible belief updating profiles, with diminished behavioral impact of evidence samples occurring late during decision formation. These same individuals also exhibited overall smaller pupil responses and less reliable pupil encoding of computational variables governing the dynamic belief updating. Our findings provide insights into the cognitive and physiological bases of psychosis proneness and open paths to unraveling the pathophysiology of psychotic disorders.
Bone mineral density as a prognostic marker in patients with biliary tract cancer undergoing surgery
Authors: Heinrichs Lisa , Fluegen Georg , Loosen Sven H. , Loberg Christina , Wittig Linda , Quaas Alexander , Plum Patrick S. , Große Hokamp Nils , Minko Peter , Krieg Andreas , Antoch Gerald , Knoefel Wolfram T. , Luedde Tom , Roderburg Christoph , Jördens Markus S. 
Published: September 2024

Abstract
Background
Biliary tract cancer (BTC) is one of the most aggressive malignancies and surgery represents the only curative treatment approach. However, even in patients with complete tumor resection 5-year survival rates are below 30%. So far, prognostic markers to assess the outcome of these patients are lacking. We therefore evaluated bone mineral density (BMD) as a prognostic tool in patients receiving surgery for BTC.

methods
76 BTC patients undergoing tumor resection in our clinic (Duesseldorf cohort) as well as an external validation cohort of 34 BTC patients (Cologne cohort) were included. BMD was analyzed at the first lumbar vertebra, using routine CT scans which has been proven comparable to DXA.

Results
Median overall survival (OS) of the Duesseldorf cohort after surgery was 527 days, one- and five-year survival probabilities were 62 and 18%. Patients with BMD above 156.5 HU had significantly improved OS (1435 days vs. 459 days; p = 0.002). The prognostic value for BMD was confirmed using Cox-regression analysis, as well as an external validation cohort. In subgroup analysis the prognostic effect of BMD was only present in female patients, suggesting sex specific differences.

Conclusion
BMD is a valuable, easily accessible and independent prognostic marker in patients receiving liver surgery for BTC.