bluuebunny/crossref_metadata_2025_split huggingface dataset:
Keterampilan Berpikir Kritis Menggunakan Model SSCS dan PPB pada Materi Jaringan Hewan
Authors: Sopia  , Listiawati Milla , Ukit  
Published: February 2025

Tujuan dari penelitian ini adalah untuk mengetahui perbedaan keterampilan berpikir kritis siswa pada kelas yang menggunakan model SSCS dan kelas yang menggunakan model PBL. Metode yang digunakan dalam penelitian ini adalah Eksperimen semu dengan design penelitian Pretest and Posttest design. Penelitian ini menggunakan sampel sebanyak 70 orang dari kelas XI MIPA 1 dan XI MIPA 2 dipilih dengan sampel purposive. indikator yang digunakan dalam penelitian ini berupa soal essay yang berindikator keterampilan berpikir kritis. Hasil penelitian ini menunjukan bahwa nilai pretest dan posttest pada kelas yang menggunakan model SSCS Sebesar 37,64 (sangat rendah) dan 89,56 (tinggi). nilai pretest dan posttest pada kelas yang menggunakan model PBL Sebesar 44,33 (sangat rendah) dan 85,44 (tinggi). Dengan H0 ditolak sehingga terdapat perbedaan antara keterampilan berpikir kritis pada kelas yang menggunakan model SSCS dan Kelas yang menggunakan model PBL. Hasil dari effect size sebesar 0,44 termasuk kedalam kategori sedang.
ОБНОВЛЕНИЕ И ВОЗРОЖДЕНИЕ НАЦИОНАЛЬНЫХ ИНДУСТРИАЛЬНЫХ КАДРОВ КАЗАХСТАНА (1991-2009 гг.)
Authors: Асылбекова Ж. , Апендиев Т. , Актамбердиева З. 
Published: February 2025

Статья посвящена изучению важных аспектов истории национальных индустриальных кадров Казахстана в 1991-2009 годы. Для современного Казахстана, как индустриально-аграрного государства, располагающего богатейшими природными ресурсами, мощным научно-техническим и экономическим потенциалом, вопрос о состоянии технических специалистов является весьма актуальным. И в прошлом, и сейчас и в перспективе, благодаря богатству и разнообразию полезных ископаемых, индустриальный прогресс Казахстана будет во многом обеспечиваться за счет ускоренного роста тяжелой индустрии, прежде всего ее топливно-энергетических отраслей, химической промышленности, а так же цветной и черной металлургии. Известно, что основным производителем материального богатства в условиях Казахстана был и остается рабочий класс. В современных условиях подготовка высококвалифицированных рабочих и специалистов из казахов становится актуальной проблемой для развития индустриальных отраслей экономики, где стали острее ощущать нехватку профессионально подготовленных кадров. Численность учащихся в общеобразовательных школах растет, число учебных заведений и учащихся в системе профессионального начального образования стабильно сокращается.
Со второй половины 1980-х и в 1990-е годы проявилась и укрепляется позитивная тенденция роста удельного веса национальных кадров в ведущих отраслях материального производства -промышленности и строительстве, хотя и он все еще был ниже, чем их доля в составе населения республики. Основную массу коллективов, как и ранее, продолжали составлять представители европейских этносов. Традиционно коренной этнос был более широко представлен в аграрном секторе экономики и на транспорте. Во-вторых, продолжался процесс перераспределения занятого населения между сферами физического и умственного труда, часть казахского этноса пополняла ряды работников интеллектуального труда. При этом, сейчас наблюдается процесс достаточно широкого вливания и адаптации коренного этноса, особенно молодежи в различных отраслях рыночных отношений. Поэтому, авторы уверены, что ядром государственной политики в области трудовых ресурсов должна стать задача создания системы качественного, профессионального образования, прежде всего, системы начальной и средней профессиональной подготовки, а также, продуманная миграционная политика.
International Prolonged Grief Disorder Scale Addendum for Refugees and Displaced people (IPGDS-ARD): A study of Arabic-speaking bereaved refugees
Authors: Killikelly Clare , Reymond Alexandra , Aeschlimann Anaïs , Maercker Andreas , Heim Eva 
Published: February 2025

Background
Prolonged grief disorder (PGD) is a new and significant addition to the ICD-11 WHO disease classification system and the DSM 5-TR. As a new disorder, it stands to improve diagnostic precision, enhance communication among health professionals and patients, provide better access to care and lead to effective treatments and intervention. However, it remains to be determined if the new diagnostic criteria for PGD are applicable to different cultural groups.

Method
Here we sought to adapt the International Prolonged Grief Disorder Scale for refugees and displaced people. We conducted two focus groups with clinicians and health care workers and six cognitive interviews with bereaved Arabic-speaking refugees.

Results
This formative research resulted in an addendum (comprised of three new scales) to the IPGDS aimed to aid with treatment planning: the 42 item Addendum for Refugees and Displaced people (IPGDS-ARD). Here we present the steps for scale augmentation based on cultural considerations, a detailed description of clinical utility, feasibility and content validity established at each step, and an analysis of the percent of change in content at each step.

Conclusion
We conclude that the presented method of scale augmentation is a feasible and efficient approach that led to a culturally relevant, clinically useful addendum to an existing PGD questionnaire.
Allegiance and treatment quality as moderators of the comparative effectiveness of psychotherapy? A systematic review and meta-analysis of studies comparing humanistic psychotherapy to other psychotherapy approaches
Authors: Schünemann Olivia , Jansen Alessa , Willutzki Ulrike , Heinrichs Nina 
Published: February 2025

Background
Achieving positive outcomes in comparative RCTs examining psychotherapy interventions may be moderated by other factors than treatments alone, namely allegiance and treatment quality (bona fide, adherence). Using the study sample of a recent comprehensive review on humanistic interventions by the German Scientific Board of Psychotherapy, we assumed that higher allegiance towards non-humanistic approaches and lower treatment quality in the humanistic intervention arm would result in worse outcomes for the humanistic groups.

Method
We included studies in which a humanistic psychotherapy (sub-)approach was compared to another type of psychotherapy. Data was extracted independently by the authors. A priori defined meta-regression analyses were performed with allegiance and treatment quality as main moderators and study quality (risk of bias), type of active control, humanistic psychotherapy and target population (children/adolescents; adults) as exploratory.

Results
The majority of studies showed non-allegiance towards humanistic intervention arms; only about half of the humanistic interventions were bona fide treatments demonstrating high percentages of potential biases in these comparative intervention studies. However, allegiance and bona fide were significant moderators only for two (allegiance) resp. one (bona fide) of five outcome comparison. Type of active control (cognitive behavioural therapy) and disorder group (anxiety disorders) emerged as further moderators.

Conclusion
We found no clear evidence for allegiance or treatment quality impacting upon treatment outcome in this re-examination. Allegiance and treatment quality were not as relevant for outcomes in this meta-analysis of RCTs as expected.
Perubahan Luas Dan Kerapatan Mangrove Di Kawasan Pesisir Kota Serang, Banten
Authors: Yudha Indra Gumay , Rahayu Risma Warni , Yuliana Darma , Damai Abdullah Aman 
Published: February 2025

Perubahan luas dan kerapatan mangrove memiliki pengaruh yang besar terhadap keberlangsungan fungsi ekosistem di wilayah pesisir. Penelitian ini bertujuan untuk menganalisis perubahan luas dan kerapatan mangrove di Kota Serang, Banten. Metode yang digunakan adalah penginderaan jauh melalui interpretasi citra Landsat 5 dan Landsat 8 dengan analisis terhadap perubahan luas dan kerapatan mangrove pada tahun 2011 dan 2021. Prosedur penelitian dilakukan dengan mengelompokkan nilai NDVI ke dalam 3 kelas vegetasi, yaitu jarang, sedang, dan rapat. Selanjutnya dilakukan ground check untuk menguji tingkat akurasi data terhadap tutupan kanopi mangrove dengan metode hemisperichal photography. Hasil penelitian menunjukkan bahwa tingkat akurasi citra pada tahun 2021 sebesar 90%. Berdasarkan analisis tersebut diketahui bahwa telah terjadi penurunan luas dan perubahan kerapatan mangrove di Kelurahan Sawah Luhur, sedangkan di Kelurahan Banten justru mengalami peningkatan. Secara umum, di wilayah pesisir Kota Serang terjadi penurunan luas mangrove antara 2011-2021 yang mencapai 13,95 ha dengan penurunan utama terjadi pada mangrove dengan kelas vegetasi jarang (33,14 ha). Sebaliknya, mangrove dengan kategori kerapatan sedang dan rapat justru meningkat hingga 19,19 ha. Penurunan luas mangrove tersebut akibat abrasi alih fungsi menjadi tambak, serta penebangan illegal. Hasil analisis juga menunjukkan bahwa korelasi nilai NDVI dengan persentase tutupan kanopi memiliki nilai 0,696 yang masuk dalam kategori kuat.
ВИКЛИКИ ВПРОВАДЖЕННЯ ПЕРСОНАЛІЗОВАНОГО НАВЧАННЯ З ВИКОРИСТАННЯМ ШТУЧНОГО ІНТЕЛЕКТУ У ВИЩІЙ ОСВІТІ
Authors: Воротникова Ірина , Дзябенко Ольга , Морзе Наталія 
Published: February 2025

Персоналізоване навчання з використанням штучного інтелекту (ШІ) визначає створення унікального навчального досвіду для кожного студента, враховуючи його інтереси, потреби, стиль навчання та рівень знань. ШІ дозволяє освітнім технологіям і ресурсам бути гнучкими, адаптованими до потреб і запитів викладачів і студентів. Використання ШІ дозволить ефективно впроваджувати інноваційні технології в освітній процес, реалізовувати персоналізоване навчання. Зміст статті розкриває ключові аспекти викликів і перешкод впровадження персоналізованого навчання з використанням ШІ на основі опитування 97 викладачів вищої школи різних спеціальностей. Основні висновки стосуються викликів та перешкод і визначення мотиваційних важелів для викладачів вищої освіти щодо запровадження ШІ для персоналізованого навчання: відсутність освітніх політик закладів з використання ШІ та адміністративної їх підтримки, відсутність достатнього фінансування, технологічної інфраструктури, підготовка викладачів та їх страх до використання ШІ, етичні і правові питання використання ШІ. Серед напрямків для реалізації персоналізованого навчання з використанням ШІ визначено: індивідуальні навчальні плани, адаптивний навчальний контент, персоналізований зворотний зв’язок, інтерактивне навчання з використанням ШІ, аналітика з використанням ШІ, персоналізовані шляхи навчання для кар’єрних цілей, аналітику на основі опрацювання великих даних. Результати статистичної обробки виявили, що більшість респондентів мають значний досвід викладання, проте використання ШІ поки що не є дуже поширеним, лише 40,2 % викладачів дали розгорнуті відповіді щодо використання цих технологій у професійній діяльності за різними напрямами реалізації персоналізованого навчання. Кластерний аналіз відкритих відповідей респондентів показав, що викладачі закладів вищої освіти мають різний рівень готовності до використання ШІ, який значною мірою залежить від їхнього досвіду, мотивації, підготовки, але готові до підвищення кваліфікації з цього питання.
Clinical response to placebo botulinum toxin injection in cervical dystonia—a systematic review and meta-analysis
Authors: Wetmore Emma , Roberts Henry , Livinski Alicia A. , Camacho Terance , Eaton Chyanne , Norato Gina , Hallett Mark , Stacy Mark 
Published: February 2025

BackgroundCervical dystonia is the most common form of focal dystonia and is the most studied neurological condition in patients receiving botulinum toxin. In clinical trials of botulinum toxin, there is a placebo response, but this has not been studied systematically.ObjectivesA systematic review and meta-analysis were conducted to assess and compare the peak and duration of placebo response in people with cervical dystonia receiving botulinum toxin in randomized, blinded controlled clinical trials.MethodsThree databases (Embase, PubMed, Scopus) and two trial registers (Cochrane CENTRAL and Cochrane Movement Disorders Trials Register) were searched by a biomedical librarian in May 2022 and September 2023. Covidence was used for screening titles and abstracts and full text. Two authors independently screened each record and collected data from the included articles. Microsoft Excel was used for data collection. The Cochrane Collaboration’s Risk of Bias tool in randomized trials was used by two authors for each included study. A third author resolved conflicts during screening and discrepancies during data collection and risk of bias assessment. We conducted a random-effects meta-analysis of the mean reduction in the TWSTRS total score at 4 weeks post injection, to assess the clinical change in the placebo arm overall and by TWSTRS pain, severity, and disability scales.ResultsTwelve studies, with moderate overall risk of bias, that included 2,145 participants with 580 randomized to placebo, were included in the systematic review. Clinical changes in the placebo arm were mild with a mean reduction of Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) total score of 3.5 [95% confidence interval (CI): 2.6–4.4] 4 weeks post injection. TWSTRS pain score at week four was 0.9 (95% CI: 0.6 - 1.1; I2 = 59%). TWSTRS severity score at week four was 1.7 (95% CI: 1.3–2.0; I2 = 63%). TWSTRS disability score at week four was 0.7 (95% CI: 0.3–1.0; I2 = 63%). Duration of benefit ranged from 45.1 to 76.3 days with a mean duration of 57.6 days. Dropouts in patients randomized to placebo were due to lack of efficacy, pain, neck weakness, fatigue, and tiredness.ConclusionThis information on placebo response will be useful in estimating sample size and interpreting participant benefit in future interventional studies of cervical dystonia.
Characterization of the gut microbiota in urinary calculi patients with preoperative urinary tract infection
Authors: Chen Hao , Yuan Jing , Zhou Hongmin , Zhan Xiangcheng , Gao Yuchen , Chen Bowen , Aihemaiti Nuer , Xu Xiao , Dong Yunze , Liu Shuai , Chen Yanhua , Liu Ding , Xie Tiancheng , Xu Yunfei 
Published: February 2025

BackgroundUrinary tract infection is one of the most common comorbidities of urinary stones. Disorders of gut microbiota can affect various infectious diseases and the formation of the stones. Therefore, alterations in the gut bacteria profile may be a potential risk factor for the development of infections in patients with urinary tract stones.MethodsWe conducted a retrospective study to analyze the association of urinary tract infections with gut microbiota and serum metabolism in patients with stones.ResultsPatients with urolithiasis were predominantly in combination with diabetes mellitus (11.4% vs. 20%) and hypertension (36.4% vs. 50%). There were no statistically significant differences in hematological and urinary parameters. Compared to negative patients, IL-17A was significantly higher in the positive group (25.0 vs 21.1 pg/ml p = 0.038). The majority of pathogens detected in urine cultures were urease-negative bacteria, and urease-positive bacteria accounted for 15% of the total number of patients. We analyzed the community composition of the two groups of patients and found a significant difference in their β-diversity (p = 0.025), suggesting that dysbiosis of the gut bacteria may be associated with the combination of urinary tract infections in urolithiasis. For identification of crucial bacteria, we found changes in the abundance of both Intestinibacter (p = 0.036) and Dialister (p = 0.039), and abundance of Intestinibacter was positively correlated with IFN-α, IL-12P70 (p&lt;0.05), and especially IL-17A (p&lt;0.01), which may result from differences in translational, ribosomal structural and biosynthetic functions in stone patients (p &lt; 0.05).ConclusionUrolithiasis with gut dysbiosis developed a higher incidence of urinary tract infections, which may be associated with the increasing of Intestinibacter and affect the expression of IL-17A by translational, ribosomal structural and biosynthetic function.
Positive association between serum lactate dehydrogenase levels and blood pressure: evidence from NHANES 2015–2016
Authors: Hu Tao , Li Linfeng , Cao Qiqiang , Tu Weiling , Huang XianTao , Yuan Tan 
Published: February 2025

BackgroundSerum lactate dehydrogenase (sLDH) is an enzyme implicated in tissue injury and inflammatory responses. Despite its established role in these pathophysiological processes, the association between sLDH and blood pressure remains underexplored. The present findings suggest that sLDH could emerge as a valuable biomarker for blood pressure regulation and may hold significant promise in the management of hypertension.MethodsOur investigation utilized data from the National Health and Nutrition Examination Survey (NHANES) 2015–2016, comprising 3,469 participants after excluding those under the age of 20, individuals on antihypertensive therapies, and cases with incomplete data. sLDH levels were categorized into tertiles, while blood pressure measurements were conducted under standardized protocols. To elucidate the relationship between sLDH levels and blood pressure, multivariate regression analyses and smooth curve fitting techniques were employed, adjusting for 17 covariates, including age, sex, and body mass index.ResultssLDH corresponds with both systolic blood pressure (SBP) and diastolic blood pressure (DBP). The adjusted smooth curve fitting diagram demonstrates a linear positive connection between sLDH and SBP, with an increment of 0.053 mmHg (95% CI: 0.032, 0.074; p &lt; 0.001) in SBP for every 1 U/L increment in LDH concentrations. The connection between sLDH and DBP is non-linear. sLDH concentrations below 123 U/L have a linear positive connection with DBP, increasing 0.079 mmHg (95% CI: 0.042, 0.115, p &lt; 0.001). When sLDH concentrations exceed 123 U/L, there is not a substantial connection with DBP (P = 0.574).ConclusionOur study demonstrates a linear positive correlation between sLDH and SBP. A non-linear association was observed between sLDH and DBP, with a positive relationship for sLDH levels below 123 U/L. These findings underscore the potential of sLDH as a biomarker for blood pressure regulation.
Relationship between ghrelin and thyroid disease: a meta-analysis
Authors: Xin Caihong , Yao Jiayi , Li Huijuan , Sun Xin , Wang Huijuan 
Published: February 2025

BackgroundPrevious studies have identified a close relationship between ghrelin levels and thyroid disease. Ghrelin levels were lower in patients with hyperthyroidism compared with healthy individuals, and increased after treatment. However, other studies have reported inconsistent results. As such, the association between ghrelin and thyroid disease remains controversial.MethodsA literature search of the Web of Science, Wiley Online Library, Embase, and PubMed databases was performed. The title or abstract search term “thyroid” was used in combination with “ghrelin”. Meta-analysis results are reported as standardized mean difference with corresponding 95% confidence interval (CI).ResultsTwenty-three studies were included in this meta-analysis. Ghrelin levels in patients with hyperthyroidism were significantly lower than those in healthy individuals (SMD: -1.03, 95% CI [-1.75, 0.32]), but significantly higher after effective treatment (SMD: 0.77, 95% CI [0.03, 1.51]). Ghrelin levels were higher, but not significantly, in patients with hypothyroidism compared with healthy controls (SMD: 0.48, 95% CI [-0.13, 1.08]).ConclusionsThis systematic review is the first to evaluate the relationship between ghrelin and thyroid disease. Determining the role of ghrelin in thyroid disease will significantly contribute to understand of symptom or pathomechanism.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024591501.
High prevalence of periodontal disease and periodontopathogen colonization in adults with autism spectrum disorder: a pilot study
Authors: Berbé Ludivine , Machouart Marie , Luc Amandine , Albuisson Eliane , Strazielle Catherine , Bisson Catherine 
Published: February 2025

IntroductionAlteration of the oral microbiome could potentially play a role in the etiology of certain patients with Autism Spectrum Disorder (ASD), similar to the established link between gut microbiota dysbiosis and ASD. Most studies have assessed oral microbiota in children only and few have explored the oral flora composition in adults with ASD.MethodsIn our study, periodontal and dental status was evaluated in 30 adults with ASD using appropriate indices. Oral microbiota samples were collected in crevicular fluid and supra-gingival plaque at inflamed sites in each patient and analyzed using PCR for bacteria and qPCR for protozoa. Demographic data, co-morbidities, medication and oral hygiene habits were also collected.ResultsA total of 86.7% of the patients recruited suffering from severe ASD had periodontal disease and 67% had a high level of supra-gingival plaque. Two major periodontopathogens belonging to the red complex, Treponema denticola and Tannerella forsythia, were both detected in the supra-gingival plaque of 86.2% of patients and in the gingival crevicular fluid of 80 and 86.7% of patients, respectively. Certain microorganisms were statistically more frequently detected in patients with digestive disorders and taking certain medications.DiscussionThe oral microbiota composition of the adults with ASD showed significant differences compared to neurotypical individuals, particularly in the prevalence of the specific microorganisms P. gingivalis, T. tenax and E. gingivalis ST1. The detection frequency of periodontitis and periodontopathogens may have been underestimated due to the lack of cooperation of the adults with ASD during clinical examination and microbiota sampling. Further studies on larger cohorts are needed to consolidate these results to gain a better understanding of variations in oral microbiota.