bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reshaping the Antarctic Circumpolar Current via Antarctic Bottom Water Export
Authors: Stewart Andrew L. , Hogg Andrew McC. 
Published: August 2017

AbstractZonal momentum input into the Antarctic Circumpolar Current (ACC) by westerly winds is ultimately removed via topographic form stress induced by large bathymetric features that obstruct the path of the current. These bathymetric features also support the export of Antarctic Bottom Water (AABW) across the ACC via deep, geostrophically balanced, northward flows. These deep geostrophic currents modify the topographic form stress, implying that changes in AABW export will alter the ocean bottom pressure and require a rearrangement of the ACC in order to preserve its zonal momentum balance. A conceptual model of the ACC momentum balance is used to derive a relationship between the volume export of AABW and the shape of the sea surface across the ACC’s standing meanders. This prediction is tested using an idealized eddy-resolving ACC/Antarctic shelf channel model that includes both the upper and lower cells of the Southern Ocean meridional overturning circulation, using two different topographic configurations to obstruct the flow of the ACC. Eliminating AABW production leads to a shallowing of the sea surface elevation within the standing meander. To quantify this response, the authors introduce the “surface-induced topographic form stress,” the topographic form stress that would result from the shape of the sea surface if the ocean were barotropic. Eliminating AABW production also reduces the magnitude of the eddy kinetic energy generated downstream of the meander and the surface speed of the ACC within the meander. These findings raise the possibility that ongoing changes in AABW export may be detectable via satellite altimetry.
Added value of 18F-FDG PET/CT in diagnosing infected hip prosthesis
Authors: Kwee Robert M , Broos Wouter AM , Brans Boudewijn , Walenkamp Geert HIM , Geurts Jan , Weijers René E 
Published: August 2017

Background The diagnosis of infected hip prosthesis is frequently not straightforward yet very important as it changes treatment. Purpose To retrospectively investigate the added value of 18F-FDG PET/CT to conventional tests including radiography, erythrocyte sedimentation rate (ESR)/C-reactive protein (CRP) testing, and joint aspiration, in diagnosing infected hip prosthesis. Material and Methods Seventy-eight hip prostheses of 78 patients (55% men; mean age = 66.5 years; age range = 30–85 years) with non-specific clinical presentation, i.e. no abscess or sinus tract communicating with the joint space at clinical examination, were analyzed. Cultures of intra-articular fluid and peri-implant tissues after revision surgery or clinical follow-up ≥6 months served as gold standard. Areas under the receiver operating characteristic curves (AUCs) of radiography, ESR/CRP testing, aspiration culture, and white blood cell (WBC) count without and with the addition of 18F-FDG PET/CT were compared. Results The addition of 18F-FDG PET/CT increased AUCs: for radiography with 0.212, P = 0.001; for ESR/CRP testing with 0.076, P = 0.072; for aspiration culture with 0.126, P = 0.032; and for aspiration WBC count with 0.191, P = 0.035. Conclusion This study shows that 18F-FDG PET/CT adds to individual conventional tests in diagnosing infected hip prosthesis. It may improve the preoperative planning and should therefore be considered in the diagnostic work-up. Future studies should define the exact place of 18F-FDG PET/CT in the diagnostic work-up of periprosthetic joint infection.
“Pharming out” support: a promising approach to integrating clinical pharmacists into established primary care medical home practices
Authors: Brunisholz Kimberly D. , Olson Jeff , Anderson Jonathan W. , Hays Emily , Tilbury Peggy M. , Winter Bradley , Rickard Josh , Hamilton Sharon , Parkin Gregory 
Published: August 2017

Objective Embedding clinical pharmacists into ambulatory care settings needs to be assessed in the context of established medical home models. Methods A retrospective, observational study examined the effectiveness of the Intermountain Healthcare Collaborative Pharmacist Support Services (CPSS) program from 2012–2015 among adult patients diagnosed with diabetes mellitus (DM) and/or high blood pressure (HBP). Patients who attended this program were considered the intervention (CPSS) cohort. These patients were matched using propensity scores with a reference group (no-CPSS cohort) to determine the effect of achieving disease management goals and time to achievement. Results A total of 17,684 patients had an in-person office visit with their provider and 359 received CPSS (the matched no-CPSS cohort included 999 patients). CPSS patients were 93% more likely to achieve a blood pressure goal < 140/90 mmHg, 57% more likely to achieve HbA1c values < 8%, and 87% more likely to achieve both disease management goals compared with the reference group. Time to goal achievement demonstrated increasing separation between the study cohorts across the entire study period ( P < .001), and specifically, at 180 days post-intervention (HBP: 48% vs 27% P < .001 and DM: 39% vs 30%, P < .05). Conclusions CPSS participation is associated with significant improvement in achievement of disease management goals, time to achievement, and increased ambulatory encounters compared with the matched no-CPSS cohort.
Development of a Computerized 4-D MRI Phantom for Liver Motion Study
Authors: Wang Chunhao , Yin Fang-Fang , Segars W. P. , Chang Zheng , Ren Lei 
Published: August 2017

Purpose: To develop a 4-dimensional computerized magnetic resonance imaging phantom with image textures extracted from real patient scans for liver motion studies. Methods: The proposed phantom was developed based on the current version of 4-dimensional extended cardiac-torso computerized phantom and a clinical magnetic resonance scan. Initially, the extended cardiac-torso phantom was voxelized in abdominal–chest region at the end of exhalation phase. Structures/tissues were classified into 4 categories: (1) Seven key textured organs, including liver, gallbladder, spleen, stomach, heart, kidneys, and pancreas, were mapped from a clinical T1-weighted liver magnetic resonance scan using deformable registration. (2) Large textured soft tissue volumes were simulated via an iterative pattern generation method using the same magnetic resonance scan. (3) Lung and intestine structures were generated by assigning uniform intensity with proper noise modeling. (4) Bony structures were generated by assigning the magnetic resonance values. A spherical hypointensity tumor was inserted into the liver. Other respiratory phases of the 4-dimensional phantom were generated using the backward deformation vector fields exported by the extended cardiac-torso program, except that bony structures were generated separately for each phase. A weighted image filtering process was utilized to improve the overall tissue smoothness at each phase. Results: Three 4-dimensional series with different motion amplitudes were generated. The developed motion phantom produced good illustrations of abdominal–chest region with anatomical structures in key organs and texture patterns in large soft tissue volumes. In a standard series, the tumor volume was measured as 13.90 ± 0.11 cm3 in a respiratory cycle and the tumor’s maximum center-of-mass shift was 2.95 cm/1.84 cm on superior–inferior/anterior–posterior directions. The organ motion during the respiratory cycle was well rendered. The developed motion phantom has the flexibility of motion pattern variation, organ geometry variation, and tumor modeling variation. Conclusions: A 4-D computerized phantom was developed and could be used to produce image series with synthetic magnetic resonance textures for magnetic resonance imaging research of liver motion.
Identifying patients with high risk of readmission from the patient navigators’ perspectives: a descriptive qualitative study
Authors: Mohd Razali Mas Rizalynda , Chong Yan Chew , Mustapha Nur Zarifah , Xu Yi , Ayoob Salimah Mohd , Lim Mei Ling , Aloweni Fazila 
Published: August 2017

Background: Unplanned readmission incurs additional cost to patients and contributes to the rising healthcare cost of our nation. Although numerous studies have investigated the predicting factors that contribute to hospital readmission, the majority of the studies focused on clinical and patient-related factors, and were not from the perspectives of clinicians such as patient navigators (PNs). Aim: To understand factors that predict patients’ readmission risks from the PNs’ perspectives. Method: Using purposive sampling, PNs with a minimum of 10 years of clinical experience in the adult acute-care setting participated in the focus group interviews. Thematic analysis was adopted. Findings: All 10 PNs agreed that the readmission risk assessment tool was useful as a guide to assess patients’ risk of readmission; however, they also mentioned the use of clinical judgement and experience while assessing their patients. Three themes emerged from this study: (1) looking beyond medical-related issues; (2) social and community support; (3) functional status of patients. Conclusion: Predicting patients’ risk of readmission is closely tied to the patients’ current medical conditions and caregiving needs. Ensuring individualised readmission risk assessment and identifying social issues early are key in ensuring a holistic discharge planning.
KIT signaling is dispensable for human mast cell progenitor development
Authors: Dahlin Joakim S. , Ekoff Maria , Grootens Jennine , Löf Liza , Amini Rose-Marie , Hagberg Hans , Ungerstedt Johanna S. , Olsson-Strömberg Ulla , Nilsson Gunnar 
Published: August 2017

Key PointsSCF and KIT signaling are dispensable for the survival, proliferation, and maturation of human mast cell progenitors.
ICAM-1–targeted thrombomodulin mitigates tissue factor–driven inflammatory thrombosis in a human endothelialized microfluidic model
Authors: Greineder Colin F. , Johnston Ian H. , Villa Carlos H. , Gollomp Kandace , Esmon Charles T. , Cines Douglas B. , Poncz Mortimer , Muzykantov Vladimir R. 
Published: August 2017

Key PointsA microfluidic model of TF-driven thrombosis allows testing of human-specific, antibody-targeted therapeutics in whole blood under flow. hTM/R6.5 inhibits inflammatory thrombosis more effectively than untargeted agents (eg, shTM) and shows synergy with supplemental PC.
Frequency-dependent velocity analysis and offset-dependent low-frequency amplitude anomalies from hydrocarbon-bearing reservoirs in the southern North Sea, Norwegian sector
Authors: Ahmad Sayyid Suhail , Brown R. James , Escalona Alejandro , Rosland Børge O. 
Published: August 2017

Our aim was to identify some of the characteristics of low-frequency anomalies. Specifically, we have looked, in 3D broadband data from the North Sea, for any offset dependence in these anomalies and any frequency-related change in normal moveout (NMO) velocity that could influence stacking power over different frequencies. After high-resolution spectral decomposition, two types of low-frequency anomaly have been identified associated with hydrocarbon-bearing reservoirs: (1) at the reservoir top and (2) below the reservoir, with a time delay of approximately 100–200 ms. Both types of anomalies indicate offset dependence. On the near-offset stacks, they are relatively strong, but they tend to be absent on the far-offset stacks. In addition, horizon velocity analysis, which was performed along the horizons picked at the tops of reservoir and nonreservoir intervals, has revealed frequency-dependent NMO velocity. For nonreservoir events, we found no significant difference between the NMO velocities for the low-frequency and high-frequency filtered common-midpoint gathers. However, along the anomalously low-frequency events observed at the tops of, and below, oil-bearing reservoirs, lower velocity is observed for low-frequency and higher velocity for high-frequency filtered gathers. If these properties turn out to be universally typical, increased understanding and inclusion of them could lead to improved workflows and help increase the reliability of low-frequency analysis as a hydrocarbon indicator.
Stepwise Synthesis and Crystal Structure of an AuI4CoIII2 Hexanuclear Complex with d-Penicillaminate and Bis(dicyclohexylphosphino)ethane
Authors: Itai Takuma , Kojima Tatsuhiro , Konno Takumi 
Published: August 2017

Abstract
The stepwise synthesis of AuI4CoIII2 complex with d-penicillaminate and 1,2-bis(dicyclohexylphosphino)ethane, [2]2+, via metalloligand approach, together with single-crystal X-ray analysis of nitrate salt, [2](NO3)2, is reported. [2](NO3)2 adopts normal alternate arrangement of cations and anions in crystal, which is different from non-alternate arrangement in corresponding AuI4CoIII2 complex with d-penicillaminate and 1,2-bis(diphenylphosphino)ethane.
A six-year retrospective analysis of cut-out risk predictors in cephalomedullary nailing for pertrochanteric fractures
Authors: Caruso G. , Bonomo M. , Valpiani G. , Salvatori G. , Gildone A. , Lorusso V. , Massari L. 
Published: August 2017

Objectives Intramedullary fixation is considered the most stable treatment for pertrochanteric fractures of the proximal femur and cut-out is one of the most frequent mechanical complications. In order to determine the role of clinical variables and radiological parameters in predicting the risk of this complication, we analysed the data pertaining to a group of patients recruited over the course of six years. Methods A total of 571 patients were included in this study, which analysed the incidence of cut-out in relation to several clinical variables: age; gender; the AO Foundation and Orthopaedic Trauma Association classification system (AO/OTA); type of nail; cervical-diaphyseal angle; surgical wait times; anti-osteoporotic medication; complete post-operative weight bearing; and radiological parameters (namely the lag-screw position with respect to the femoral head, the Cleveland system, the tip-apex distance (TAD), and the calcar-referenced tip-apex distance (CalTAD)). Results The incidence of cut-out across the sample was 5.6%, with a higher incidence in female patients. A significantly higher risk of this complication was correlated with lag-screw tip positioning in the upper part of the femoral head in the anteroposterior radiological view, posterior in the latero-lateral radiological view, and in the Cleveland peripheral zones. The tip-apex distance and the calcar-referenced tip-apex distance were found to be highly significant predictors of the risk of cut-out at cut-offs of 30.7 mm and 37.3 mm, respectively, but the former appeared more reliable than the latter in predicting the occurrence of this complication. Conclusion The tip-apex distance remains the most accurate predictor of cut-out, which is significantly greater above a cut-off of 30.7 mm. Cite this article: G. Caruso, M. Bonomo, G. Valpiani, G. Salvatori, A. Gildone, V. Lorusso, L. Massari. A six-year retrospective analysis of cut-out risk predictors in cephalomedullary nailing for pertrochanteric fractures: Can the tip-apex distance (TAD) still be considered the best parameter?. Bone Joint Res 2017;6:481–488. DOI: 10.1302/2046-3758.68.BJR-2016-0299.R1.
Maximising available resources: Equality and human rights proofing Irish fiscal policy
Authors: Murphy Mary P. 
Published: August 2017

Abstract
The paper examines various rationales for applying equality and human rights proofing mechanisms to fiscal policy. The principle of using available resources to the maximum to progressively realise human rights, and not to erode the revenue capacity of developing nations to do likewise, is at the heart of emerging human rights norms. To date, Irish budgetary processes and major policy statements such as the Commission on Taxation or the draft outline National Plan on Business and Human Rights Strategy have not engaged with the principles of maximising available resources or extraterritoriality. Proofing fiscal policy is also relevant from the perspective of fiscal welfare where taxation instruments, traditionally used as a revenue-gathering mechanism, are increasingly used as distributional mechanisms to achieve policy outcomes in pensions, health, housing and employment, with important equality and distributive dimensions, particularly from gender, age and socioeconomic perspectives. A number of practical institutional mechanisms and evaluative questions can guide equality and human rights proofing of fiscal policy, but commitments to maximise resources to realise rights also need to be promoted through a public discourse which sees taxation as potential investment in society rather than a burden or cost on the economy.
An extension of a variant of d’Alemberts functional equation on compact groups
Authors: EL-Fassi Iz-iddine , Chahbi Abdellatif , Kabbaj Samir 
Published: August 2017

Abstract
All paper is related with the non-zero continuous solutions f : G → ℂ of the functional equation

f
(
x
σ
(
y
)
)
+
f
(
τ
(
y
)
x
)
=
2
f
(
x
)
f
(
y
)
,

x
,
y
∈
G
,

$${\rm{f}}({\rm{x}}\sigma ({\rm{y}})) + {\rm{f}}(\tau ({\rm{y}}){\rm{x}}) = 2{\rm{f}}({\rm{x}}){\rm{f}}({\rm{y}}),\;\;\;\;\;{\rm{x}},{\rm{y}} \in {\rm{G}},$$

where σ; τ are continuous automorphism or continuous anti-automorphism defined on a compact group G and possibly non-abelian, such that σ2 = τ2 = id: The solutions are given in terms of unitary characters of G:
Asymptotic normality of conditional distribution estimation in the single index model
Authors: Hamdaoui Diaa Eddine , Bouchentouf Amina Angelika , Rabhi Abbes , Guendouzi Toufik 
Published: August 2017

Abstract
This paper deals with the estimation of conditional distribution function based on the single-index model. The asymptotic normality of the conditional distribution estimator is established. Moreover, as an application, the asymptotic (1 − γ) confidence interval of the conditional distribution function is given for 0 < γ < 1.
Some conditions under which derivations are zero on Banach *-algebras
Authors: Hosseini Amin 
Published: August 2017

AbstractLet 𝒜 be a Banach *-algebra. By 𝒮𝒜we denote the set of all self-adjoint elements of 𝒜 and by 𝒪𝒜we denote the set of those elements in 𝒜 which can be represented as finite real-linear combinations of mutually orthogonal projections. The main purpose of this paper is to prove the following result:Suppose that𝒪𝒜¯=𝒮𝒜$\overline {{\cal O}_{\cal A} } = {\cal S}_{\cal A }$and {dn} is a sequence of uniformly bounded linear mappings satisfyingdn(p)=∑k=0ndn−k(p)dk(p)${\rm{d}}_{\rm{n}} ({\rm{p}}) = \sum\nolimits_{{\rm{k}} = 0}^{\rm{n}} {{\rm{d}}_{{\rm{n}} - {\rm{k}}} ({\rm{p}}){\rm{d}}_{\rm{k}} ({\rm{p}})} $, where p is an arbitrary projection in 𝒜. Then dn(𝒜) ⊆ ∪ϕ∈Φ𝒜ker ϕ for each n ≥ 1. In particular, if 𝒜 is semi-prime and further, dim(∪ϕ∈Φ𝒜ker ϕ) ≤ 1, then dn= 0 for each n ≥ 1.
Fallacious Node Algorithm for Performance Enhancement in Optical-Burst-Switching Networks
Authors: Saini Hardeep Singh , Wason Amit 
Published: August 2017

Abstract
In this paper, fallacious node algorithm is formulated for performance enhancement of an optical-burst-switching (OBS) network. With the procedural and observational analysis, we have demonstrated that the blocking probability is extremely unnoticeable, during a call establishment, while collectively discarding the faulty nodes from the selected paths. There may be distinguishing values of blocking probability because of random value of congestion on each path. The blocking probability is restrained so as not to be more than 10 % on several values on traffic and congestion. The blocking probability diminishes and becomes imperceptible with the incorporation of fallacious node algorithm and subsequently the performance of optical network is highly aggrandized. Thus the fallacious node algorithm manifests incredible prospects for optical networks as the key features such as the accessibility; sustainability and reliability of the network are highly appreciated and upgraded.
Adverse pregnancy outcomes and inherited thrombophilia
Authors: Dłuski Dominik , Mierzyński Radzisław , Poniedziałek-Czajkowska Elżbieta , Leszczyńska-Gorzelak Bożena 
Published: August 2017

Abstract

Aim:
(1) To evaluate the prevalence of inherited thrombophilia in pregnant women with adverse pregnancy outcomes: intrauterine growth retardation (IUGR), preeclampsia (PE) and placental abruption. (2) To assess the impact of inherited thrombophilia on the nature of obstetric complications. (3) To assess levels of protein S, protein C, antithrombin III and homocysteine in pregnant women with adverse pregnancy outcomes.

Subjects and methods:
The study comprised 162 pregnant women. The patients were divided into three test groups and one control group. In all 162 patients the following tests were completed: activated protein C resistance (APC-R), the level of free protein S, activity of protein C, antithrombin III and the level of homocysteine. The data were statistically analyzed via χ2 of independence or homogeneity test.

Results:
In 32 of 162 patients participating in clinical research thrombophilia was diagnosed (10 patients with APC-R, 21 patients with protein S deficiency, one patient with hyperhomocysteinemia): seven patients belonged to the control group and 25 patients had diagnosed adverse pregnancy outcomes (P=0.04). In 32 patients with diagnosed thrombophilia, level of protein S was decreased (P=0.04). Protein S deficiency was diagnosed, when level of protein S was lower than 30% in the second trimester and lower than 24% in the third trimester. The incidence of activated protein C resistance caused by the mutation of factor V Leiden was in six patients (5.9%) with adverse pregnancy outcomes, and in four patients (6.6%) from the control group. Results were not statistically significant. No protein C deficiency was diagnosed (diagnosis: level<60%), but in 50% of patients with thrombophilia level of protein C was over the norm (P=0.02). The level of antithrombin III was often decreased in patients with preeclampsia – (32.4%), then in the other patients – (17.2%) (P=0.04), but no patient was diagnosed with antithrombin III deficiency (diagnosis: level<60%).

Conclusions:
Tests for thrombophilia should be carried out in women with adverse pregnancy outcomes in their history, who are planning pregnancy, to start anticoagulant prophylaxis. Our study supports the thesis that tests for thrombophilia should be carried out in women with a history of adverse pregnancy outcomes and who are planning a pregnancy to start anticoagulant prophylaxis.
The role of territorial capital in building the competitive advantages of Podkarpackie Voivodeship
Authors: Dąbrowska Anna , Szlachta Jacek 
Published: August 2017

AbstractIn the discussion of regional development factors in recent years, more and more importance has been attributed to territory, locality, site specificity and endogenous resources, as evidenced on theoretical grounds by the concept of territorial capital (Camagni 2008) and regional, place-based policy. This article aims to identify the elements of territorial capital that play a key role in the process of changing the development path of an underdeveloped region - Podkarpackie - as well as ascertaining what consequences territorial capital has for development planning within regional policy. The research highlights the importance of the immobile and intangible development factors - a high level of social capital, extensive networks and the ability to cooperate - which have helped to eliminate the limitations resulting from the weakness of other factors (especially material factors, such as private capital and low GDP).