bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants Of Msmes Welfare Through Sharia Financial Literacy In Ultra-Micro Financing
Authors: Hasan Asyari , Nasution Siti Sarah , Nasution Hairatunnisah , Arafah Santi 
Published: October 2024

This research aims to determine how much influence sharia financial inclusion, financial experience and financial management have on the welfare of MSMEs through sharia financial literacy at PT. Pegadaian Syariah Langsa. This research uses a quantitative approach using 88 MSME actors who are registered in Ultra Micro financing. Based on cross section data using analysis techniques in the form of SEM-PLS. The results of the research analysis conducted with 5% alpha show that sharia financial literacy moderates by strengthening the relationship between sharia financial inclusion and sharia financial experience on the welfare of MSMEs, while sharia financial literacy neither strengthens nor weakens the relationship between financial management and the welfare of MSMEs. The welfare of MSMEs is based on a good and increasing condition of productive businesses owned by individuals and / or individual business entities that have micro business criteria must be based on an understanding of sharia financial literacy, because sharia financial literacy is a fundamental factor for economic growth and financial stability in sharia
Automedicación y complicaciones en la salud en la zona rural del oriente de El Salvador
Authors: Bermúdez de Díaz Fátima Elizabeth , Campos Hernández Maximiliano Enrique 
Published: October 2024

Resumen: La automedicación representa un desafío significativo para las sociedades globales dado el creciente número de individuos que optan por esta práctica sin la prescripción ni supervisión de profesionales de la salud. Este comportamiento conlleva riesgos potenciales para la salud, ya que implica la ingestión de medicamentos sin la debida evaluación clínica y orientación médica. Objetivo: Describir la automedicación y su relación con las complicaciones de la salud de los habitantes del área rural de la zona oriental de El Salvador, generando la pregunta de investigación: ¿cuál es la relación de la automedicación con las complicaciones de la salud de los habitantes de la zona oriental de El Salvador? Materiales y métodos: Para el desarrollo de la investigación se utilizó el enfoque cuantitativo con la finalidad de usar procesos estadísticos para el análisis y procesamiento de la información, con una metodología deductiva que permitió servir de guía para la recolección de la información. Resultado: A través del análisis y procesamiento de la información recopilada se pudo identificar que un alto porcentaje de la población encuestada posee un grado “Básico” de estudios académico. En cuanto a las razones para automedicarse predomina la “Falta de tiempo” de los participantes para acudir a un centro asistencial y ser atendidos por el personal de Salud. Conclusiones: La automedicación es la actividad en la que las personas ingieren medicamentos sin haber recibido una receta dispensada por un médico. Esta práctica conlleva riesgos directos para la salud de la población.

Fecha de recepción: 21/11/2023
Aceptación de originales: 25/06/2024
RESÍDUOS SÓLIDOS E O DISTANCIAMENTO SOCIAL OCASIONADO PELA PANDEMIA DA COVID-19: UM BREVE PANORAMA SOCIOAMBIENTAL E UM ESTUDO DE CASO DO MUNICÍPIO DO RIO DE JANEIRO
Authors: Silva Melanie Lopes da , Cocchiarelli Sara dos Santos Barreto , Castro Rebeca de Oliveira , Araújo Fábio Vieira de 
Published: October 2024

As medidas restritivas de circulação de pessoas ocasionadas pela pandemia da COVID-19 fez com que parte da população permanecesse em casa, diminuindo o fluxo de pessoas nas ruas. Para compreender a influência das mudanças de comportamento da população na geração de resí­duos sólidos, a presente pesquisa objetivou reunir informações sobre produção e descarte de resí­duos sólidos durante o distanciamento social a fim de verificar se houveram mudanças nos hábitos de consumo de produtos e descarte de resí­duos. A pesquisa foi elaborada a partir de revisão bibliográfica e uma sondagem de público sobre o comportamento da população em relação aos resí­duos sólidos em plataforma digital. Os dados coletados mostram que o serviço de delivery aumentou após o iní­cio do distanciamento social, bem como a demanda por embalagens descartáveis, especialmente as de plástico. Por outro lado, aumentou a competitividade entre os trabalhadores do ramo de delivery e houve piora nas condições de trabalho. O volume de resí­duos sólidos em áreas urbanas e nas praias diminuiu, enquanto o volume de resí­duos enviados para a coleta seletiva aumentou. Neste perí­odo, novos tipos de resí­duos passaram a ser vistos em ruas e praias, máscaras e luvas descartáveis. Conclui-se que este é um momento importante para a sociedade e os entes públicos tratarem do consumo e descarte de resí­duos sólidos a fim de não agravar ainda mais os problemas relacionados aos resí­duos; os hábitos individuais são importantes e todos devem buscar melhorar o comportamento em relação ao meio ambiente, no entanto, uma mudança significativa e duradoura deve contar com o poder público, indústria e o comércio, que regem os comportamentos da população. A polí­tica deve ser um instrumento de transformação e melhoria social, devendo os cidadãos atuarem sujeitos ativos, capazes de questionar e propor mudanças.
EXTRAÇÃO MINERAL DE CAULIM: LEGISLAÇÃO, PROCESSO PRODUTIVO E IMPACTOS AMBIENTAIS
Authors: Silva Edmar do Nascimento , Soares Ilton Araújo 
Published: October 2024

Este artigo teve como objetivo analisar os aspectos legais e identificar os principais impactos ambientais adversos da atividade mineradora de caulim. A pesquisa foi realizada no municí­pio de Junco do Seridó, localizado no estado da Paraí­ba. Inicialmente, por meio de uma revisão bibliográfica, buscou-se conhecer conceitos importantes relacionados a impactos ambientais. Em seguida foi realizada uma consulta í s Leis e Decretos em vigor no Brasil que regem a atividade econômica mineral e comparada com a realidade existente na área de estudo, através de buscas processuais das empresas atuantes no municí­pio, realizadas no site da Agência Nacional de Mineração. A pesquisa evidenciou a discrepância entre a rigorosidade da legislação vigente e a realidade existente na exploração mineral de caulim no municí­pio de Junco do Seridó, visto que a maioria das empresas não tem licença ambiental. Foram identificados os seguintes impactos ambientais adversos: degradação da paisagem, poluição do ar, erosão e contaminação do solo e redução da biodiversidade local. Em relação ao processo de produção, observaram-se algumas práticas benéficas que estão sendo adotadas pelas empresas, como a substituição dos fornos de lenha pelos secadores a céu aberto e o reaproveitamento de toda água utilizada no beneficiamento do caulim. O único rejeito produzido e que é um passivo ambiental preocupante é o rejeito mineral que fica a disposição em montes próximos í s unidades de beneficiamento e seus territórios de exploração. Por fim, para mitigação dos impactos identificados torna-se necessário o licenciamento ambiental das empresas de mineração e a elaboração e execução de planos de monitoramento e recuperação de áreas degradadas.
Coronary artery disease and the risk of life-threatening cardiac events after age 40 in long QT syndrome
Authors: Barsheshet Alon , Goldenberg Ilan , Bjelic Milica , Buturlin Kirill , Erez Aharon , Goldenberg Gustavo , Chen Anita Y. , Polonsky Bronislava , McNitt Scott , Aktas Mehmet , Zareba Wojciech , Golovchiner Gregory 
Published: October 2024

Background and aimsLong QT syndrome (LQTS) and coronary artery disease (CAD) are both associated with increased risk of ventricular tachyarrhythmia. However, there are limited data on the incremental risk conferred by CAD in adult patients with congenital LQTS. We aimed to investigate the risk associated with CAD and life threatening events (LTEs) in patients with LQTS after age 40 years.MethodsThe risk of LTEs (comprising aborted cardiac arrest, sudden cardiac death, or appropriate defibrillator shock) from age 40 through 75 years was examined in 1,020 subjects from the Rochester LQTS registry, categorized to CAD (n = 137) or no-CAD (n = 883) subgroups.ResultsSurvival analysis showed that patients with CAD had a significantly higher cumulative event rate of LTEs from 40 to 75 years (35%) compared with those without CAD (7%; p &lt; 0.001 for the overall difference during follow-up). Consistently, multivariate analysis showed that the presence of CAD was associated with a 2.5-fold (HR = 2.47; p = 0.02) increased risk of LTEs after age 40 years. Subgroup analyses showed that CAD vs. no CAD was associated with a pronounced &gt;4-fold (p = 0.008) increased risk of LTEs among LQTS patients with a lower-range QTc (&lt;500 ms). The increased risk of LTEs associated with CAD was not significantly different among the 3 main LQTS genotypes. Patient treatment was suboptimal, with only 63% on β-blockers and 44% on non-selective β-blockers.ConclusionsOur findings suggest that CAD is associated with a higher risk of LTEs in LQTS patients, with the risk being more pronounced in those with QTc &lt;500 ms.
Refeeding partially reverses impaired fracture callus in undernourished rats
Authors: Botega Iara I. , Guedes Patrícia M. S. G. , Ximenez João Paulo B. , Zamarioli Ariane , Volpon José B. 
Published: October 2024

BackgroundAdequate nutritional intake plays a crucial role in maximizing skeletal acquisition. The specific effects of a general food restriction and refeeding on fracture healing are yet to be fully understood. The aim of this study was to assess the impact of general food restriction and refeeding on fracture repair.MethodsFifty-four male Wistar Hannover rats were randomly assigned into three groups: (1) Sham: Sham rats with femoral fracture; (2) FRes: Food-restricted rats with fracture, (3) Fres+Ref: Fres rats with refeeding. Following weaning, the FRes and Fres+Ref groups received 50% of the food amount provided to the Shams. In the sixth week of the experiment, all animals underwent a mid-right femur bone fracture, which was subsequently surgically stabilized. Following the fracture, the Fres+Ref group was refed, while the other groups maintained their pre-fracture diet. Bone calluses were analyzed on the fifth-day post-fracture by gene expression and on the sixth-week post-fracture using dual-energy X-ray absorptiometry, morphometry, histomorphometry, immunohistochemistry, computed microtomography, and torsion mechanical testing. Statistical significance was determined at a probability level of less than 0.05, and comparisons were made using the ANOVA test.ResultsFood restriction resulted in significant phenotypic changes in bone calluses when compared to sham rats characterized by deterioration in microstructure (i.e., BV, BV/TV, Tb.N, and Conn.D) reduced collagen deposition, bone mineral density, and mechanical strength (i.e., torque at failure, energy, and stiffness). Moreover, a higher rate of immature bone indicated a decrease in bone callus quality. Refeeding stimulated bone callus collagen formation, reduced local resorption, and effectively restored the microstructural (i.e., SMI, BCa.BV/TV, Tb.Sp, Tb.N, and Conn.D) and mechanical changes (i.e., torque at failure, energy, and angular displacement at failure) caused by food restriction. Despite these positive effects, the density of the bone callus, collagen deposition, and OPG expression remained lower when compared to the shams. Gene expression analysis didn’t evidence any significant differences among the groups.ConclusionsFood restriction had detrimental effects on osseous healing, which was partially improved by refeeding. Based on these findings, new research can be developed to create targeted nutritional strategies to treat and improve fracture healing.
The association between triglyceride-glucose index and gallstones: NHANES 2017-2020
Authors: Gong Li , Fan Shujin , Peng Zhenfei , Chen Zeyao , Liu Yuzhou , Huang Yinluan , Wang Chaofan , Piao Chunli 
Published: October 2024

ObjectsIt remains unclear whether the triglyceride-glucose (TyG) index has correlations with gallstones. This study aimed to investigate the association between TyG index and gallstones.MethodsData was obtained from the 2017-2020 National Health and Nutrition Examination Survey (NHANES). Participants who provided complete data about TyG index and gallstones were included in the analysis. Multivariable regression analysis and subgroup analysis were preformed to estimate the relationship between TyG index and gallstones. Restricted cubic splines (RSC) was employed to calculate the cut off value.ResultsThe TyG index was independently associated with gallstones and demonstrates a clear positive correlation (OR = 1.10; 95% CI: 1.01–1.21; p = 0.033). The threshold value is 8.98, showing a positive correlation between TyG index and gallstones when the TyG index is less than 8.98 (Log likelihood ratio P &lt; 0.001). Subgroup analysis indicates that the correlation between TyG and gallstones is mainly observed in individuals with obesity, females, younger individuals, and those with normal blood sugar levels, with these subgroups all acting as mediators between TyG and gallstones.ConclusionsHigher TyG index was linked to a higher chance of developing gallstones. Managing insulin resistance (IR) could help reduce the risk of gallstones since the TyG index is an indicator of IR.
Multiparametric quantitative MRI of healthy adult pancreas: correlations with gender and age
Authors: Wang Lixia , Liang Lu , Zhang Jiyang , Wu Chaowei , Zhou Yang , Yu Yang , Zhang Chen , Jeon Christie Y. , Jiang Tao , Gaddam Srinivas , Xie Yibin , Pandol Stephen J. , Yang Qi , Li Debiao 
Published: October 2024

BackgroundThe pancreas plays an important role in the nutrition and metabolism of the whole body. Many disease processes including obesity, diabetes mellitus (DM), acute or chronic pancreatitis, and pancreatic carcinoma result in abnormality of pancreas morphology and function. Magnetic resonance imaging (MRI) provides quantitative parameters including T1, T2, and apparent diffusion coefficient (ADC) values for evaluating normal and abnormal pancreas. Based on the normal range of these quantitative parameters, pancreatic abnormality could be detected early. However, the range and the relationship of T1, T2, and ADC values with gender and age groups using the same dataset have not been explored.PurposeTo establish the ranges of MRI tissue and functional parameters, including T1, T2, and ADC values, in healthy adult pancreas and their correlations with gender, subregion, and age.Materials and methodsThe T1, T2, and ADC values of healthy pancreas in 86 adults were measured using a 3.0-T MRI scanner. The average T1, T2, and ADC values were obtained in the whole pancreas and subregions (head, neck, body, and tail). Their correlations with gender and age were investigated.ResultsThe T1, T2, and ADC values of the whole pancreas from all subjects were 870.07 ± 61.86 ms, 44.07 ± 6.14 ms, and 1.072 ± 0.212 × 10−3 mm2/s, respectively. T2 values were significantly different between genders (P &lt; 0.05). No significant differences were found between subregions. The T1, T2, and ADC values differed significantly among the age groups (P &lt; 0.05). The T1 value revealed a moderately positive correlation, while the T2 and ADC values displayed negative correlations with age (r = 0.31, −0.45, and −0.39, respectively). The combination of T1, T2, and ADC values achieved the highest AUC value and showed a significant difference compared to T1, T2, and ADC values alone in predicting age older than 45 years.ConclusionThis study established the normal ranges of T1, T2, and ADC. We found that T2 is different between men and women, and T1, T2, and ADC are age-dependent. These results could be useful for quantitative MRI of pancreatic disease.
Efficacy and safety of very early rehabilitation for acute ischemic stroke: a systematic review and meta-analysis
Authors: Lou Ying , Liu Zhongshuo , Ji Yingxiao , Cheng Jinming , Zhao Congying , Li Litao 
Published: October 2024

BackgroundEarly rehabilitation after acute ischemic stroke (AIS) contributes to functional recovery. However, the optimal time for starting rehabilitation remains a topic of ongoing investigation. This article aims to shed light on the safety and efficacy of very early rehabilitation (VER) initiated within 48 h of stroke onset.MethodsA systematic search in PubMed, Embase, Cochrane Library, and Web of Science databases was conducted from inception to January 20, 2024. Relevant literature on VER in patients with AIS was reviewed and the data related to favorable and adverse clinical outcomes were collected for meta-analysis. Subgroup analysis was conducted at different time points, namely at discharge and at three and 12 months. Statistical analyses were performed with the help of the Meta Package in STATA Version 15.0.ResultsA total of 14 randomized controlled trial (RCT) studies and 3,039 participants were included in the analysis. VER demonstrated a significant association with mortality [risk ratio (RR) = 1.27, 95% confidence interval (CI) (1.00, 1.61)], ability of daily living [weighted mean difference (WMD) = 6.90, 95% CI (0.22, 13.57)], and limb motor function [WMD = 5.02, 95% CI (1.63, 8.40)]. However, no significant difference was observed between the VER group and the control group in adverse events [RR = 0.89, 95% CI (0.79, 1.01)], severity of stroke [WMD = 0.52, 95% CI (−0.04, 1.08)], degree of disability [RR = 1.06, 95% CI (0.93, 1.20)], or recovery of walking [RR = 0.98, 95% CI (0.94, 1.03)] after stroke. Subgroup analysis revealed that VER reduced the risk of adverse events in the late stage (at three and 12 months) [RR = 0.86, 95% CI (0.74, 0.99)] and degree of disability at 12 months [RR = 1.28, 95% CI (1.03, 1.60)], and improved daily living ability at 3 months [WMD = 4.26, 95% CI (0.17, 8.35)], while increasing severity of stroke during hospitalization [WMD = 0.81, 95% CI (0.01, 1.61)].ConclusionVER improves activities of daily living (ADLs) and lowers the incidence of long-term complications in stroke survivors. However, premature or overly intense rehabilitation may increase mortality in patients with AIS during the acute phase. PROSPERO registration number: CRD42024508180.Systematic review registrationThis systematic review was registered with PROSPERO (https://www.crd.york.ac.uk/PROSPERO/). PROSPERO registration number: CRD42024508180.
The benefits of photobiomodulation in animal models of multiple sclerosis: a systematic review and meta-analysis
Authors: Ahmed Zubair 
Published: October 2024

BackgroundPhotobiomodulation (PBM), using red- or near-infrared light, has been used to treat tendinopathies, nerve injuries, osteoarthritis and wounds and evaluated in experimental allergic encephalomyelitis (EAE). To date, only a few studies have been performed in EAE but surprisingly, a few clinical studies in humans have already been performed, despite the paucity of preclinical evidence.ObjectiveTherefore, this study systematically reviewed the usefulness of PBM in ameliorating the clinical signs of EAE, a commonly used animal model of multiple sclerosis, and determine if there is enough evidence to warrant human studies.MethodsPubMed, EMBASE and Web of Science were searched in July 2024 for studies relating to PBM and EAE without any language restrictions. Since only three studies have been published, all studies were included in the systematic review and data related to clinical signs of EAE was pooled together to conduct a meta-analysis. Non-homogenous data was also reported and thematically synthesized.ResultsA meta-analysis of the pooled data from the three included studies demonstrated a significant reduction of the clinical severity of EAE, with a mean reduction of 1.44, 95% CI (−2.45, −0.42), p = 0.006. PBM also significantly reduced other parameters such as infiltration of mononuclear cells, CNS demyelination, apoptosis markers and pro-inflammatory cytokines. However, there was an overall high risk of bias in all of the studies.ConclusionThe meta-analysis supports the use of PBM to ameliorate the symptoms of EAE, but the paucity of studies and the high risk of bias in the included studies warrants further preclinical investigation before conducting human studies.
Effect of fatigue on intermuscular EMG-EMG coupling during bench press exercise at 60% 1RM workload in males
Authors: Wang Lejun , Tao Haifeng , Chen Qing , Qiao Minjie , Song Xiaoqian , Niu Wenxin 
Published: October 2024

ObjectiveTo explore the neuromuscular control mechanism and quantifying the fatigue response during bench press exercise is important references to prescribe an appropriate exercise program. However, current literature struggles to provide a concrete conclusion on the changes of intermuscular EMG-EMG coupling between synergistic and antagonist muscles during the exercise. Thus, the current study was designed to reveal fatigue-related changes of intermuscular EMG-EMG coupling during bench press exercise.MethodsThirty-one healthy male participants performed a bench press exercise on the Smith machine at 60% One Repetition Maximum (1RM) workload to exhaustion, while surface electromyographic signals (sEMG) were collected from triceps brachii (TB), biceps brachii (BB), anterior deltoid (AD), posterior deltoid (PD), and pectoralis major (PM). Surface EMG signals were divided into the first half and second half of the bench press exercise. Phase synchronization index (PSI) was calculated between sEMG of synergistic muscle pairs AD-TB, AD-PM and antagonist muscle pairs BB-TB, AD-PD.ResultsEMG power of TB, AD, PD, PM muscles in alpha (8–12 Hz) frequency band and EMG power of each muscle in beta (15–35 Hz), and gamma (35–60 Hz) frequency bands were all increased during the second half of contraction compared with the first half of contraction. PSI of gamma frequency band was significantly decreased in BB-TB muscle pair while EMG-EMG coupling of AD-TB in gamma frequency band was significantly increased during the second half of contraction compared to the first half of contraction.ConclusionsThe results indicated a decrease of interconnection between synchronized cortical neurons and the motoneuron pool of BB and TB, and an increase of interconnection between AD-TB muscles during fatiguing bench press exercise at 60% 1RM workload. The changes of intermuscular coupling may be related to the supraspinal modulations to compensate for the decrease of muscle force as well as a result of unbalanced changes of agonist and antagonist muscle contractility.