bluuebunny/crossref_metadata_2025_split huggingface dataset:
Антимікробна активність нового хіміотерапевтичного препарату на основі флюмеквіну щодо Aeromonas Hydrophila
Authors: Solopova H. , Vishchur O. , Stetsko T.I. , Ugrin G.P. , Hom’jak O.I. 
Published: November 2017

In the article presented results of study of the antimicrobial activity of the chemotherapeutic drug on the basis of the active substance – flumequine.The sensitivity of the microflora of the biomaterial to antibiotics was determined and the minimum inhibitory concentrations of flumequin, the active substance of the drug «Flyumek», were determined.For the study were selected 5 fish – carps affected by aeromonosis. The diagnosis for aeromonosis was based on epizootological data, clinical signs of the disease, pathological and anatomical changes and the results of bacteriological research. The fish were slaughtered and crops were made from the affected parts of the skin, liver and kidneys. Sowing was carried out on meat-peptone broth (MPB) and meat-peptone agar (MPA). The seeds were incubated in a thermostat at a temperature of 26 °C for 48 hours. The sensitivity of the microflora of the biomaterial to antibiotics was determined by agar diffusion using standard antibiotic disks and the Müller-Hinton medium. In order to isolate and identify the Aeromonas hydrophila bacterium, the primary culture of the pathological material was performed on the MPA, which was incubated in the thermostat at 26 °C for 24 hours. The next step was to isolate pure cultures of microorganisms and make smears that were stained with Gram in the Björk modification. The method of serial dilutions in a liquid nutrient medium was determined by the minimum inhibitory concentrations (MICs) of flumequine in the preparation of «Flyumek» for Aeromonas hydrophila isolates.The results of the test for the sensitivity of the microflora of the biomaterial from the patient to the aeromonosis of the fish showed high sensitivity of the microorganisms to flumequin, tetracycline, fluorophenicol and trimethoprim, moderate neomycin sensitivity and resistance to amoxicilline, tylosine, lincomycine and colistine. The diameter of the growth retardation zone around the disks with flumequin was – 23,2 mm in the crop sown from the skin, from the kidneys – 30,0 mm, from the liver – 30,4 mm.According to the obtained values of the minimum inhibitory concentrations of flumequine, all investigated isolates of Aeromonas hydrophila were sensitive to the drug «Flyumek» and amounted to 1.0–2.0 μg ml.The results of the conducted studies indicate that fluoroquinolone antibiotic flumequin has a high antimicrobial activity against the bacterium Aeromonas hydrophila, an aeromonosis agent of carp fish.
Біохімічні показники крові свиноматок за профілактики порушень обміну мінеральних речовин
Authors: Grushanska N.G. , Kostenko V.М. 
Published: November 2017

Of all domestic animals, pigs suffer the most from deficiency of minerals. This is due to the specificity of pig production, feeding technology, retention and anatomical – physiological characteristics of pigs. In order to obtain the best qualities of pig production, it is necessary to make correction the ration for swines of various technological groups using mineral feed additives that take into consideration not only the physiological needs for minerals of the corresponding age groups and classes of swines but also the biogeochemical zone or the province where the farm is located. Also, conditions that accompany the emergence of a mineral deficit are taken into account. The development of new, eco-friendly, non-toxic means of preventing disorders of metabolism of minerals in pigs is a promising direction of veterinary medicine.The research was carried out ont the farm of the Kyiv region (northeastern biogeochemical zone). Biochemical parameters of blood were studied using biochemical analyzer «Labline-010» with standard sets of reagents. The content of chemical elements in water was investigated by the method of atomic emission spectrometry on the Optima 210 DV device.The paper presents the authors’ own research on determining the biochemical status of an organism of lactating sows in the northeastern biogeochemical zone of Ukraine at the prevention of microelementosis using new experimental eco-friendly means.The content of total protein, albumin, glucose, total calcium, inorganic phosphorus, cholesterol, bilirubin, activity of ALT, AST, AF in the blood serum of sows of the northern-eastern biogeochemical zone of Ukraine before and after the application of experimental drugs was investigated. The positive influence of prophylactic agents on the parameters of metabolism of proteins and calcium was defined.In the blood serum of the sows of the first experimental group, 28 days later, the total protein content on 5.3% lower and the total calcium concentration on 16.5% higher than the control group of animals were found.In the blood serum of sows in the second experimental group, 28 days later, the total protein content on 8.3% lower and the total calcium concentration on 19.9% higher than the control group of animals were found.
Ріст і розвиток організму кролів за випоювання сполук силіцію
Authors: Ivanitskaya A.I. , Lesyk Ya.V. , Kropyvka S.Y. , Hoivanovych N.K. 
Published: November 2017

The purpose of the study was to investigate the effect of putting up for 58 days life of various amounts of nanosilicon citrate infusion obtained by the method using nanotechnology and metasilicate sodium, on the growth and development of the body of the rabbits of the Hyla 110 of the diurnal age. The rabbits of the control group fed without restriction a balanced granulated feed with free access to water. Animals of the experimental groups I, II and III fed feed of the control group's diet and, during the day, dispensed the citrus application, accounting for 25; 50 and 75 μg Si/kg body weight. The females of the IV and V experimental groups feed the diet of the control group and set the sodium metasilicate (Na2SiO3H2O) with water in an amount of 2.5 and 5.0 mg Si/kg body weight, respectively. The trial lasted 68 days, including a preparatory period of 10 days, an experimental one of 58 days. On the 110-th day of life, animals of all groups were killed to determine the mass indices of carcasses, internal organs and skin. Exposure of nanosilicon citrate to animals in the I, II, and III experimental groups during 58 days was characterized by an increase in body weight of 4.0; 9.5 and 8.9%, while the use of sodium metasilicate in IV and V groups increased by 3.1 and 4.2% compared with the control group. The carcass weight correlation was correlated with body weight and in animals of groups ІІ and ІІІ, respectively, was higher by 10.6 and 9.0%, while in other experimental groups it was greater in the range from 2.4 to 2.9% compared with control. Research on the development of the body of rabbits indicated a tendency to a higher level of body mass index and internal organs in animal experimental groups than in the control, although the more pronounced differences were in rabbits I–III groups, which were deposited on nanosilicon citrus application. Ribbons infusion of citrate in comparison with metasilicate of sodium and control group, to a greater extent influenced the mass of the skin and the mass of the liver, which was reflected in an increase (P < 0.05) of their mass on 110 days of life. The use of an organic compound of silicon in the amount of 50 and 75 μg Si/kg of body weight, during 58 days, contributed to the activation of metabolic processes in the skin. Perhaps higher (P < 0.05) indices of the thickness of the dermis and subcutaneous fat and the total thickness of the skin of rabbits compared with the control group were established. The conducted studies showed more pronounced positive effects on the growth and development of the body of rabbits of the organic compound of silicon in the amount of 50 and 75 μg Si/kg body weight in comparison with its inorganic compound and control group.
Поширення та причини захворювань кінцівок у великої рогатої худоби
Authors: Mysak A.R. , Krupnyk Y.G. , Tsisinska G.V. , Dudchak I.P. , Lenjo Y.M. 
Published: November 2017

Frequent cases of limb disease in cattle constitute a significant economic and veterinary problem. In most pathological processes are localized in the distal part of the limb. So in cases of dairy complexes cases of lesions of tissues of fingers in cows is 20–25%; in particular, the ulcer of Rostergolts is diagnosed at 15–65%.It is known that in the pathogenesis of purulent-inflammatory processes in the distal part of the limbs in cows play the association of fungi and bacteria possessing keratolytic properties.In the structure of limb diseases, diseases of the infectious and non-infectious origin of joints occupy a significant place. Depending on the conditions of retention, the incidence of arthritis can range from 3 to 12%. The causes of diseases are, for the most part, a high level of injury, sensitization of the body, caused by antigenic loading and reduced immunological reactivity of the organism.Cases of the disease in arthritis of infectious etiology are especially frequent in calves. And, quite often, in the presence of prenatal infection in newborn calves, cases of polyarthritis is occurring.Arthritis processes of non-contagious etiology are often recorded especially in conditions of malnutrition due to the lack of mineral substances and vitamins (in the first place vitamin D) and lack of active exercise. In this case, the pathological process, as a rule, acquires signs of osteochondrosis and is recorded mainly in the multistory of their layer joints with a tight articulation of their separate layers (wrist, wrists). Such a defeat is often interpreted as an arthrosis which is false.Chronic insecticidal processes in the joints, the basis of which pathogenesis is dystrophic-degenerative changes in cattle for osteodystrophy are found in all animals. It was set up that the manifestation of the disease can be both in clinical and subclinical forms. Clinically, the disease manifests itself as a violation of the static and dynamic functions of the limbs, an increase in the value of individual joints, a decrease in productivity, and so on. The basis of the subclinical form of the disease is the damage to subchondral bone tissue and cartilage. In some farms, animals are tied up, especially at the end of the winter-stool period, Osteochondrosis (osteochondropathy), including a subclinical form, can cover up to 100% of the livestock population. After all, in the development of pathology, in addition to the generally recognized etiological factors of osteodystrophy (lack of Ca, P, vitamin D), the importance of a set of a number of factors. In particular, the following factors influence on the occurrence of diseases of the limbs in cattle, such as: feeding conditions, content, environment, seasonality, age and physiological state of the animal, concomitant diseases and genetic predisposition. Violations and changes in the latter may cause disease of the limbs of a mass character, which leads to significant economic losses.
Характеристика сучасних методів визначення сирого протеїну у кормах та рослинній сировині
Authors: Kuchnir G.V. , Levytzkiy Т.R. , Ryvak G.P. , Kurylas L.V. , Vilha O.M. , Fedor G.Y. 
Published: November 2017

Todays in laboratory and manufacturing practice of veterinary medicine of Ukraine, for the detertimations of raw protein in feed and in plant raw are used as classic and as modern methods depending from the aim and the task of research. Thats why the article describes the modern methods of the determination of content of nitrogen and the calculation of raw protein in feeds for animals and in plant materials, in particular, photometric, classical – Kjeldahl method, modern – Dumas and spectrometric methods (the method of infrared spectrometry in the near range (NIR-spectrometry). Despite of the facts, that the Kjeldahl method remains generally accepted in the determination of the protein and is most often used in research, but the modern methods – the Dumas method and NIR-spectrometry are widely adopted in laboratory practice. The main advantage of these methods is the speed of the analysis (the one definition takes only a few minutes), practically there is no sample preparation, and the most important is that the toxic chemicals and catalysts are not used.Thus, despite the fact that the Kjeldahl method remains generally accepted in the determination of the protein, and it is most frequently used in research, but modern methods, the Dumas method and NIR-spectrometry, are widely implemented in laboratory practice. The main advantage of these methods is the speed of conducting the analysis (one definition only takes a few minutes), there is practically no sample preparation, and most importantly, toxic chemicals and catalysts are not used.
Вплив уведеного сухостійним коровам трутенату на вміст цинку, купруму і мангану в крові, материнській частині плаценти і перебіг отелення
Authors: Kruty S.I. 
Published: November 2017

In the experiment carried out on three groups of dry cows 6 goals in each, the influence of introducing of Trutenat to them on the content of Zincum, Cuprum and Mangan in carunculs of the placenta maternal part and the course of calving researched. The drug is not introduced to cows of control groups, the first group with course of physiological calving and the third at detention of the placenta, and the second group was injected three times at intervals of 7 days, were injected subcutaneously Trutenat in a dose of 7 ml/100 kg of body weight. At all cows throughout 30–45 minutes after birth of the calf we exterpited 2 caruncles, in which we determined the mineral content. The level fluctuation of the test substances in carunculs depending on the current third stage of calving set. The concentration of Zincum in carunculs of cows during the detention of the placenta is higher than in cows of the second (experimental) and the first (control) groups, and Cuprum is lower compared to the first and the second control group, Mangan – below relative to both control groups.The physiological calving courses with different concentration of Zn (61.45 ± 1.34 μmol/l), Cu (0.73 ± 0.1 μmol/l) and Mn (213.3 ± 2.7 μmol/l) in carunculs of the placenta maternal part. The second stage of calving of all cows was within the physiological framework without rendering assistance, ranged from 57 to 85 minutes and amounted 67.5 minutes to an average.Depending on the duration of the third stage of calving we determined the relationship of the studied mineral substances between their levels in blood and maternal parts of the placenta. On the pathology of the third stage of calving in cows blood in the first stage the level of Zinc amounted to 134.15 µg%, Cuprum –90.8 µg %, Mangan –to 3.7 µg%. Separation of the placenta lasted longer for 20–22 hours.
Ефективність аерозольного внутрішньоматкового препарату «Метразол-біо» при ендометриті у корів
Authors: Sachuk R.N. , Kulinich O.V. , Katsaraba O.A. 
Published: November 2017

In the study of obstetric-gynecological pathology in cows of experimental farms, it was determined that endometritis is 28,2% in the overall structure of the diseases. The peak disease incidence of cows is recorded at the end of the winter (standstill) period (32,2%), the lowest percentage of registered pathologies - the end of the summer-pasturing period (2,7%), which is due to inobservance with sanitary-hygienic maintenance requirements (feeding, exercise, insolation). A new scheme of treatment of endometritis with the use of the drug «Metrazol-bio» is proposed, which includes chlorhexidine bichluconate, dexpanthenol and Taurian worm's essential oil, a combination of which has a synergistic effect. It was established that intrauterine application of the aerosol preparation «Metrazol-bio» in combination with subcutaneous injections of the proparanil-containing uterotonical drug «Uterodevu» reduces the treatment period by 4 days, shows reduction of the service period by 18,57±6 days and reduces the index of insemination of cows at 0,4 times as compared with control animals receiving conventional therapy: «Chlorhexidine bigliuconate 0,05%» and the hormonal drug «Oxytocin». The increase in hemoglobin content was noted at 17,9%, the number of red blood cells – 38,1%, and the reduction of leukocytes – 29,8% in blood, compared with the traditional method of treatment. Further research will be aimed at the clinical trial of the drug «Metrazol-bio» in the treatment of cervicitis and vaginitis of cows.
Біоморфологія м’язів, діючих на плечовий суглоб чорнодзьобої гагари
Authors: Melnyk O.O. , Melnyk M.V. 
Published: November 2017

The article presents the results of studies of the biomorphological features of muscles acting on shoulder joint of some representatives of order Gaviiformes. Shoulder joint is a multifaceted joint, movements of which are provided not only by the muscles of the shoulder joint itself, but also some muscles of the shoulder girdle and elbow joint. It should be noted that the main muscles of the flight of birds are muscles of the shoulder girdle, in particular: thoracic and m. supracoracoideus. Also important are some of the muscles of the elbow, in particularm.coraco-radialis and m. scapula-triceps This is confirmed both by the points of fixation, and the degree of their development.The degree of development and differentiation of muscles acting on the shoulder joint is different, which is due to the peculiarities of the wing operation during the flight, and in waterfowl – peculiarities of underwater swimmingusing wings. The aim of this biomorphological study was understanding of development degree, and the main, mechanisms of differentiation and transformation of muscles acting on the shoulder joint of birds adapted to the aquatic habitat.Material for research was obtained from the funds of the Department of anatomy of Animals named after acad. V.G. Kasyanenko of the National University of Life and Environmental Sciences of Ukraine, where the muscle structures of the shoulder joint were studied on black-tailed gagar Gavia immer in number of 3 individuals. Birds of Gaviiformes order are characterized by a rapid, but little maneuverable flight. They are extremely well adapted to the aquatic environment and spend most of their lives in the water, leaving on land only during breeding. These birds perfectly swim and dive, and during diving use not only the pelvic fins but also the wings. This, in turn, imposes certain imprints on the degree of development and differentiation of the studied muscle groups. It was found that among the studied groups of muscles (shoulder girdle, shoulder and elbow joints) the most developed group of muscles is shoulder girdle – 86%. The muscle groups of the elbow – 8.5% and the shoulder – 5.4% of the joints are significantly less. In addition, for the first time, we have found that the largest in its development among all the muscles examined - the thoracic muscle (the group of muscles of the shoulder girdle) has significant differences in comparison with other species of birds. These differences consist in the fact that this muscle is clearly differentiated into two separate layers, in fact two separate muscles – superficial and deep, most of which are developed superficial. Such a differentiation is due to biomorphological adaptations to the habitat.
Якісний склад молока голштинських корів залежно від паратипових і генотипових факторів
Authors: Milostiviy R.V. , Karlova L.V. , Sanzhara R.A. 
Published: November 2017

Studied level of milk production and milk quality of Holstein breed depending on origin and linear conditioning animals. Found that the largest average daily milk production of cow enough adult Danish, German and Hungarian origin surpassed the requirements of the standard breed at 7.9; 8.8 and 6.9 kg or 32.5; 29.7 and 35.1%. Their daughter exceeded breed standard at 9.2; 8.8 and 11.1 kg or 36.1; 36.0 and 40.5%, respectively.On the content of fat in milk breed standard (3.6%) match only imported cows and their daughter of Danish and German breeding. However, the import of cows from the Danish, German and Hungarian origin protein content in milk was below the standard of the breed to 0.2; 0.4 and 0.2%; animals first generation on this indicator inferior requirement standard 0.1, respectively; 0.5 and 0.8%. The fat content in the milk turned out to be higher in imported cows and their daughters Starbuck line 352790.79 (3.6 and 3.7%). On the content of protein in milk cows imported lines have supremacy Bella 1667366.74 (3.1%). Moderately high content of this component in milk observed in cows patriotic line generation Eleveyshn 1491007.65 (3.2%). The most nutritious milk from cows imported turned out to line Cheef 1427381.62 (61.2 kcal/100 g). They also differed with significant content of nonfat milk solids (8.42%). Starbuck’s daughter 352790.79 surpassed their mothers on the content of the skimmed milk residue (8.45%) is water.High in lactose different imported cows lines Cheef 1427381.62 and Bella 1667366.74 (4.63%). in turn, the only daughter of the Starbuck 352790.79 line proved to be the best on the content of milk sugar.The data obtained is cut off the opportunity to conduct breeding work to improve desired traits.
Оцінка безпечності кормової добавки Ліатоксил для курчат-бройлерів
Authors: Levytskyy T.R. 
Published: November 2017

The research was conducted on the basis of the vivarium of the State Scientific-Research Control Institute of Veterinary Preparations and Feed Additives. To carry out researches, a feed additive of Lyophthixil produced by Sanofort-P was used. Feed supplement Lytaxyl is a powder of gray color with a specific odor. The composition of the feed supplement includes zeolite, bentonite, silicon oxide, fumaric acid, citric acid, and succinic acid. Research liatoksil feed additive on the safety for the target species – to broiler chickens. Research conducted by 30 heads of broiler chickens of 8-day age of which was formed three groups of 10 goals each. The total duration of the experiment – 35 days. Scheme trials included three groups: a control group that received no feed additives; the first experimental group that received the recommended dose; second experimental group that received feed supplement at a dose which is 10 times the recommended dose. For targets were: the general state bird, bird preservation, hematological parameters. At the end of the experiment studied the internal organs. As a result of studies found that the introduction of a feed additive Liatoksil feed for broiler chickens at a dose of 20 g/kg of feed has no negative influence on the general condition, survival, growth and development, hematological indices and state of the internal organs of broiler chickens. Feed additive liatoksil has a sufficient margin of safety and is safe for broiler chickens five times the recommended dose.
Необхідність удосконалення системи моніторингу токсикантів в Україні
Authors: Nazar B.I. 
Published: November 2017

The article presents the main methodological approaches and criteria for the necessity of development and introduction of the State Toxicological Monitoring of Forms in Ukraine, including GMOs, taking into account the requirements for sampling, criteria for determining its periodicity, risk analysis, requirements for testing laboratories.The main components and goals of the complex system of state monitoring of sources of GMOs in feed, feed additives, premixtures for farm animals and poultry are presented. The main methodical approaches and criteria for the development and implementation of the State monitoring of feed in the GMO content in Ukraine are given, taking into account the requirements for the selection of samples, the determination of the frequency of their selection, and the analysis of risks at all stages of the chain «production – consumption».Implementation of toxicological monitoring, including monitoring of sources of GMOs in feeds, will ensure awareness, and in the future ensure the protection of human, animal and natural environment, will create conditions for the safe practical use of GMOs for economic purposes, prevent uncontrolled use of GMO sources feed.