bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of exogenous phytase supplementation on production performance of commercial broiler
Authors: Parvin E , Khatun MA , Yeasmin T , Sharmin MM 
Published: January 2017

An experiment was conducted to investigate the effect of supplementing of exogenous phytase enzyme on productivity of commercial broilers. Four strains of commercial broiler such as Fast feather, Arbor acres, Cobb-500 and Hubbard classic each having 78 numbers were reared for a period of 5 weeks. A total number of 312 day old broiler chicks were distributed into two dietary treatments i.e. basal diet (Control-T0) and basal diet supplemented with phytase enzyme 1g/kg feed (supplemented-T1). The results indicated that broilers fed on diets supplemented with phytase have gained more body weight when compared with control group (P<0.05). The first and second highest body weights were recorded for the strains Cobb-500 and First feather broilers, respectively, which feed on diet containing phytase. Feed consumption varied significantly between the broilers on different dietary regimes. Significant differences (P<0.01) were found in feed conversion ratios among the birds fed on diet with phytase enzyme. The lowest feed conversion ratio was in Cobb-500 fed on phytase diet where as the highest was in Fast Feather provided with only basal diet during the 5th week of age. Average feed conversion ratios were 1.73 and 1.86 for the supplemented and control group respectively. Use of phytase as feed additive in the diet resulted in high profitability/ broiler. Net profit per live broiler was the also higher in treatment group compared with control groups of birds. The highest net profit per live broiler was observed in Arbor Across strains fed on phytase diet. The result of the present study suggests that the addition of dietary phytase enzyme in the diet of broiler may increase the production performance and reduce the cost of production.Bang. J. Anim. Sci. 2016. 45 (3): 31-39
THE GRAVITATIONAL INTERACTION BETWEEN PLANETS ON INCLINED ORBITS AND PROTOPLANETARY DISKS AS THE ORIGIN OF PRIMORDIAL SPIN–ORBIT MISALIGNMENTS
Authors: Matsakos Titos , Königl Arieh 
Published: January 2017

ABSTRACT
Many of the observed spin–orbit alignment properties of exoplanets can be explained in the context of the primordial disk misalignment model, in which an initially aligned protoplanetary disk is torqued by a distant stellar companion on a misaligned orbit, resulting in a precessional motion that can lead to large-amplitude oscillations of the spin–orbit angle. We consider a variant of this model in which the companion is a giant planet with an orbital radius of a few astronomical units. Guided by the results of published numerical simulations, we model the dynamical evolution of this system by dividing the disk into inner and outer parts—separated at the location of the planet—that behave as distinct, rigid disks. We show that the planet misaligns the inner disk even as the orientation of the outer disk remains unchanged. In addition to the oscillations induced by the precessional motion, whose amplitude is larger the smaller the initial inner-disk-to-planet mass ratio, the spin–orbit angle also exhibits a secular growth in this case—driven by ongoing mass depletion from the disk—that becomes significant when the inner disk’s angular momentum drops below that of the planet. Altogether, these two effects can produce significant misalignment angles for the inner disk, including retrograde configurations. We discuss these results within the framework of the Stranded Hot Jupiter scenario and consider their implications, including the interpretation of the alignment properties of debris disks.
An Integrated Workflow To Assess Technical and Biological Variability of Cell Population Frequencies in Human Peripheral Blood by Flow Cytometry
Authors: Burel Julie G. , Qian Yu , Lindestam Arlehamn Cecilia , Weiskopf Daniela , Zapardiel-Gonzalo Jose , Taplitz Randy , Gilman Robert H. , Saito Mayuko , de Silva Aruna D. , Vijayanand Pandurangan , Scheuermann Richard H. , Sette Alessandro , Peters Bjoern 
Published: January 2017

Abstract
In the context of large-scale human system immunology studies, controlling for technical and biological variability is crucial to ensure that experimental data support research conclusions. In this study, we report on a universal workflow to evaluate both technical and biological variation in multiparameter flow cytometry, applied to the development of a 10-color panel to identify all major cell populations and T cell subsets in cryopreserved PBMC. Replicate runs from a control donation and comparison of different gating strategies assessed the technical variability associated with each cell population and permitted the calculation of a quality control score. Applying our panel to a large collection of PBMC samples, we found that most cell populations showed low intraindividual variability over time. In contrast, certain subpopulations such as CD56 T cells and Temra CD4 T cells were associated with high interindividual variability. Age but not gender had a significant effect on the frequency of several populations, with a drastic decrease in naive T cells observed in older donors. Ethnicity also influenced a significant proportion of immune cell population frequencies, emphasizing the need to account for these covariates in immune profiling studies. We also exemplify the usefulness of our workflow by identifying a novel cell-subset signature of latent tuberculosis infection. Thus, our study provides a universal workflow to establish and evaluate any flow cytometry panel in systems immunology studies.
Customized Liquid Ocular Prosthesis for Anophthalmic Patients suffering from Dry Eye: A Clinical Research
Authors: Aggarwal Richa , Gupta Rubina , Bharat Arjun , Nijhawan Sushil 
Published: January 2017

ABSTRACT

Problem
Prosthetic eyes often cause dryness, irritation, and inflammation of the anophthalmic sockets.

Purpose
To reduce the discomfort caused due to dryness of ocular prosthesis by a custom-made hollow ocular acrylic prosthesis, which is filled with lubricant drops slowly and systemically released into the ophthalmic cavity upon blinking.

Materials and methods
Thirty-eight patients wearing unilateral artificial eye for a period of more than 6 months were evaluated. An innovative customized hollow prosthesis is described, which was incorporated with a hollow reservoir containing a combination of a tear substitute along with cyclosporine A (0.05%) acting as the lubricant. The patients were then evaluated with the help of a questionnaire, regarding the comfort, dryness, soreness, and the ease of use of prosthesis. A self-formulated grading system was used to record the scores.

Results
Postinsertion of this hollow prosthesis, there was a marked reduction in the dryness, irritation, discomfort, and signs of inflammation.

Conclusion
It was concluded that the continuous flow of the lubricant onto the dry prosthetic eye helps in reducing dryness, irritation, soreness, and inflammation.

Clinical implications
A hollow ocular prosthesis that can continuously discharge lubricant onto the dry prosthesis can help in increasing patient's acceptance and comfort.

How to cite this article
Gupta R, Aggarwal R, Bharat A, Nijhawan S. Customized Liquid Ocular Prosthesis for Anophthalmic Patients suffering from Dry Eye: A Clinical Research. Int J Prosthodont Restor Dent 2016;6(3):57-62.
Time-dependent Variation in Compressive Strengths of Three Posterior Esthetic Restorative Materials: An in vitro Study
Authors: Mishra Sunil , Sharma Anjna , Mishra Pankaj 
Published: January 2017

ABSTRACT

Aim
To compare the compressive strengths of composite resins and resin-modified glass ionomer cements (RMGICs) at different times.

Materials and methods
A total of 36 samples were prepared, 12 samples of each group, composite resins Filtek Z 250, Filtek Z 350, and resin-modified glass ionomer cement. Compressive strengths of specimens were measured after 1, 24 hours, and 7 days. Test was carried out on a “Universal Testing Machine” with cross-head speed of 5 mm/min.

Results
There was a significant difference between all the three restorative materials. Analysis of variance showed that mean compressive strengths of Z 250 after 1, 24 hours were higher than Z 350 and RMGIC (p < 0.05). The mean compressive strengths were reduced after 7 days in all the three groups, but after 7 days, the values of Z 250 when compared with the Z 350 and RMGIC were higher.

Conclusion
The study demonstrated that compressive strengths of hybrid composite resins (Z 250) were significantly higher than that of nanocomposites (Z 350) and RMGIC.

How to cite this article
Sharma A, Mishra P, Mishra SK. Time-dependent Variation in Compressive Strengths of Three Posterior Esthetic Restorative Materials: An in vitro Study. Int J Prosthodont Restor Dent 2016;6(3):63-65.
Cone Beam Computed Tomography-guided Management of Cervical Perforative Internal Resorption in Permanent Mandibular First Molar
Authors: Naik Rasika A , Ramugade Manoj M , Attar Nilofar B , Sapkale Kishor D 
Published: January 2017

ABSTRACT
Internal resorption in the permanent dentition is a rare pathologic condition. Clinical differentiation of perforative cervical internal resorption from cervical external resorption is considered to be a challenging task. Advanced imaging techniques, such as cone beam computed tomography (CBCT) have proven vital diagnostic tools in the detection and management of these lesions. Management of a perforated internal resorption needs comprehensive endorestorative and periodontal approach. This article describes 1 year follow-up of the successfully managed perforative cervical internal resorption in permanent mandibular first molar. The affected tooth was endodontically treated, and the resorptive defect was restored with resin-modified glass ionomer cement (RMGIC) through periodontal flap surgery.

How to cite this article
Naik RA, Ramugade MM, Attar NB, Sapkale KD. Cone Beam Computed Tomography-guided Management of Cervical Perforative Internal Resorption in Permanent Mandibular First Molar. Int J Prosthodont Restor Dent 2016;6(3):73-77.
Histological Evaluation of a Novel Pulpotomy Technique with Low-level Laser Therapy and Its Comparison with Formocresol: A Randomized Animal Trial
Authors: Prabhakar AR , Shagale Amitha M 
Published: January 2017

ABSTRACT
Aim
Low-level laser therapy (LLLT) has been increasingly used over the past few decades in both medicine and dentistry. It has been suggested that LLLT may be helpful in pulpal wound healing following pulp exposure. The purpose of this study was to evaluate the histological changes in dental pulp tissue after a pulpotomy procedure using a low-level diode laser in comparison with the gold standard formocresol.

Materials and methods
In this experimental split-mouth study, 20 teeth were randomly selected from five dogs. The animals were anesthetized and pulpotomized using a low-level diode laser (660 nm, 36 mW) and formocresol respectively. One week later, the pulpotomized teeth were extracted and subjected to histological evaluation. Histological changes seen in the pulp tissues of all the interventional groups were subjected to statistical analysis using Mann–Whitney U test for pairwise comparison; p < 0.05 was considered as statistically significant and p > 0.05 nonsignificant.

Results
On histologic evaluation, least amount of inflammation and maximal healing was evident in the LLLT group. On the contrary, the formocresol group showed severe inflammation.

Conclusion
Low-level laser therapy promises to be a safe, minimally invasive, yet maximally effective modality for pulpotomy.

How to cite this article
Prabhakar AR, Shagale AM, Yavagal C. Histological Evaluation of a Novel Pulpotomy Technique with Low-level Laser Therapy and Its Comparison with Formocresol: A Randomized Animal Trial. Int J Laser Dent 2016;6(1):1-5.
Etiopathology of Hoarseness of Voice: A Clinical Study
Authors: Rao Syamji V , Sharma Varanasi S , Rao MV Subba , Keerthi GS , Deta Sheeba I , Seepana Pravin T 
Published: January 2017

ABSTRACTAimHoarseness of voice is generally due to change in quality of voice. The etiology of hoarseness of voice varies from benign conditions to malignant disease, hence should not be ignored. All cases of hoarseness of voice persisting for more than 3 weeks should be investigated for the underlying disease. It may indicate either malignancy of larynx or silent bronchogenic carcinoma. A retrospective study of cases of hoarseness of voice was done in MediCiti Institute of Medical Sciences for a period of 5 years. The etiopathological factors, age and duration of presentation, and type of condition were analyzed to arrive at different etiopathological conditions responsible at different age groups.How to cite this articleRao SV, Sharma VS, Rao MVS, Keerthi GS, Deta SI, Seepana PT, Kumar V. Etiopathology of Hoarseness of Voice: A Clinical Study. Int J Phonosurg Laryngol 2016;6(2):64-67.
Our Approach for Optimizing Vocal Outcomes in Transoral Laser Microsurgical Resection of Early Glottic Carcinoma
Authors: Deshmukh Shraddha 
Published: January 2017

ABSTRACT

Objectives
To assess oncologic and functional outcomes of early glottic cancer cases treated with transoral laser microsurgical resection (TLMR) and to outline the principles for optimizing vocal outcomes in these cases.

Materials and methods
Sixty six patients with early glottic cancer (7 CIS, 43 T1a, 15 T1b, 1 T2) underwent TLMR. Postoperatively, voice quality was assessed by Oates Russell Voice Profile.

Results
Local control was achieved in 95.08% of the cases and larynx was preserved in 98.3%. Residual disease developed in 3 patients. There were eight local recurrences. Single patient of T1b lesion was lost to follow-up and came back with stridor and underwent total laryngectomy.

Conclusion
Early glottic cancers can be effectively treated by TLMR with good oncologic outcome. Depth of infiltration of lesion is the most critical factor affecting the postoperative vocal outcome. In our study near-normal conversational voice to moderate change in voice was found after type I, II, and III cordectomies. Surprisingly, type VI cordectomy also gave a serviceable vocal outcome with moderate change in voice. In our opinion, type IV cordectomy does not give a serviceable vocal outcome even if performed unilaterally. Thus radiotherapy should be strongly considered in such cases for better vocal outcome.

How to cite this article
Nerurkar NK, Deshmukh S. Our Approach for Optimizing Vocal Outcomes in Transoral Laser Microsurgical Resection of Early Glottic Carcinoma. Int J Phonosurg Laryngol 2016;6(2):68-72.
Montgomery T-tube for Management of Tracheal Stenosis: A Retrospective Analysis in a Government Hospital of South India
Authors: Babu Myle Mahesh 
Published: January 2017

ABSTRACTThis study investigated the outcome of patients who developed tracheal stenosis after tracheostomy or intubation using Montgomery T-tube. We reviewed 21 patients who had experienced tracheal stenosis at a single institution, over 7 years from January 2008 to January 2015. Majority were in the age group of 20 to 30 years and a male preponderance was noted. The duration between extubation and appearance of respiratory symptoms ranged from 32 to 96 days. Location of stenosis was more common in subglottic region (61.9%), followed by tracheal (33.33%) and laryngotracheal stenosis (4.7%). At the end of 6 months, 18 of 21 patients were decannulated successfully and 3 were decannulated at the end of 9 months. Our study showed that use of Montgomery T-tube for laryngotracheal stenosis gave complete improvement in all the patients. Tracheal resection and anastomosis is the definitive surgical treatment of choice in tracheal stenosis but when surgical management is not feasible T-tube is a good alternative and T-tube as front line of management has produced complete improvement in airway patency and restoration of voice in our study.How to cite this articleBabu MM, Kumar RA, Thirugnanamani R. Montgomery T-tube for Management of Tracheal Stenosis: A Retrospective Analysis in a Government Hospital of South India. Int J Phonosurg Laryngol 2016;6(2):73-77.
Clinical Outcomes at 1 Year following Corneal Ectasia Treatment with Accelerated Transepithelial Cross-linking
Authors: Pérez-Cambrodí Rafael J , Ruiz-Fortes Pedro , Artola Alberto 
Published: January 2017

ABSTRACT

Objective
To assess the clinical outcomes in ectatic corneas following accelerated transepithelial cross-linking (CXL) over 1 year of follow-up.

Materials and methods
Twenty-one eyes diagnosed with progressive corneal ectasia (19 keratoconus, 2 post-laser in situ keratomileusis ectasias) in 14 patients aged between 26 and 69 years were enrolled. All cases were treated with accelerated transepithelial CXL using the Avedro KXL® system (Waltham, MA, United States). Changes at visual, refractive, corneal topographic, and corneal aberrometric level were evaluated over a 12-month follow-up period. The demarcation was also determined using optical coherence tomography (OCT).

Results
The mean depth of the demarcation line measured by OCT was 202.72 µm, varying between 153 and 230 µm. One month postsurgery, a change was noted at the limit of statistical significance in sphere (p = 0.05) and in spherical equivalent (p = 0.05). Likewise, a statistically significant difference was observed in corrected distance visual acuity (CDVA) (p = 0.01). There were no significant changes in either visual acuity or refraction between 1 and 6 months (p ≥ 0.35). Although changes in trend were observed in corneal topographic and aberrometric parameters after surgery, none reached statistical significance (p ≥ 0.08). A significant change was observed only in astigmatism of the posterior surface between 1 and 12 months (p = 0.02).

Conclusion
Accelerated transepithelial CXL may be a useful technique for the management of progressive corneal ectasia, as it is able to maintain the topographic and aberrometric profile of the cornea with no significant changes. Longer-term studies are required to confirm this finding

How to cite this article
Piñero DP, Artola A, Ruiz-Fortes P, Soto-Negro R, Pérez-Cambrodi RJ. Clinical Outcomes at 1 Year following Corneal Ectasia Treatment with Accelerated Transepithelial Cross-linking. Int J Kerat Ect Cor Dis 2016;5(3):93-98.
Femto Circular Keratotomy to Halt the Progression of Keratoconus I and II
Authors: Krumeich Jörg H , Hirnschall Nino , Breyer Detlev , Laufer Florian 
Published: January 2017

ABSTRACTAimTo simplify and enhance safety in the generation of a stabilizing intracorneal scar by circular keratotomy (CKT). A femtosecond laser was used to perform individually sized intraparenchymal cuts.Materials and methodsAs equipped, the Ziemer Z6 femto-second laser cuts a 400-µm-deep incision with a diameter of 7.0 mm around the optical axis. The epithelium, Bowmann's membrane, the internal borders of Descemet's membrane, and the endothelium are not affected.The 3-, 6-, and 12-month postoperative values were compared with the 1-month postoperative keratometric readings and astigmatism. The preoperative best corrected visual acuity (BCVA) with glasses was compared with the values found at the same time points as noted above.ResultsStatistical evaluation indicated that keratometry within ±1.5D remained in 96.6, 93.1, and 96.6% of cases at the 3-, 6-, and 12-month time points respectively.Astigmatism was stable at the same time points in 100, 95.8, and 92.3%.The BCVA improved in 12 cases throughout the first post-operative year (48%, n = 25); however, 11 cases did not change (44%) and 2 cases lost at least one line (8.0%).ConclusionFemto CKT halts the progression of keratoconus for at least 1 year in 96.6% of cases. This treatment provides keratometric and refractive stability for over 1 year. This result, in conjunction with the significant improvement in BCVA, demonstrates the potential of this method for patients with stage I and II keratoconus.How to cite this articleKrumeich JH, Hirnschall N, Breyer D, Laufer F. Femto Circular Keratotomy to Halt the Progression of Keratoconus I and II. Int J Kerat Ect Cor Dis 2016;5(3):109-113.
Keratoconic Bi-aspheric Contact Lenses
Authors: Gordon-Shaag Ariela , Fine Philip , Gantz Liat , Gideon-Abousaid Arige , Serero Gad 
Published: January 2017

ABSTRACT

Aim
This observational clinical case series examined patients with keratoconus (KC) fit with keratoconic bi-aspheric (KBA) lenses to assess visual acuity (VA), wavefront aberrations, physiological fitting, subjective comfort, and manufacturer's fitting guidelines.

Materials and methods
Seven adult patients (11 eyes, four females, mean age: 34.15 ± 14.12) with nipple cones from the Hadassah Academic College contact lens clinic (Jerusalem, Israel) were fit with KBA lenses by modifying the initial base curve (BC) to obtain an acceptable physiological fit. The uncorrected and corrected distance (D) and near (N) Snellen VA and the ocular wavefront measurements, and responses to a self-administered five-point scale questionnaire were compared after 2 weeks of wear using paired two-tailed t-test or Mann-Whitney U test, as appropriate.

Results
Visual acuity and total root mean square (RMS) improved significantly with the lenses (DVAuncorrected = 0.04 ± 0.02, DVAcorrected = 0.66 ± 0. 22, NVAuncorrected = 0.34 ± 0.30, NVAcorrected = 0.95 ± 0.12). Subjects reported an average of 7.0 ± 2.7 hours of wear daily, with good scores in visual stability, satisfaction with VA and quality of vision, improvement of mood and quality of life, and low scores in foreign body sensation, pain, red eye, and itching during wear, and difficulty with lens removal. An average of two BC modifications from the diagnostic lens were necessary (0.16 mm steeper in nine eyes, 0.27 mm flatter in two eyes).

Conclusion
Keratoconic bi-aspheric lenses can provide 7 hours of comfortable wear, significantly improved VA and total RMS aberrations, alongside subjective satisfaction. Base curve modifications can be reduced by fitting a diagnostic lens 0.75 mm steeper than the flattest keratometry reading.

How to cite this article
Gantz L, Gordon-Shaag A, Gideon-Abousaid A, Serero G, Fine P. Keratoconic Bi-aspheric Contact Lenses. Int J Kerat Ect Cor Dis 2016;5(3):132-138.
Reviewer Acknowledgements
Authors: Young Daisy 
Published: January 2017

Business and Economic Research (BER) would like to thank the following reviewers for reviewing manuscripts from January 1, 2014, to May 31, 2014. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether IJSSS publishes their work, appreciate the helpful feedback provided by the reviewers. Macrothink Publishing appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. AlunicaMorariuAnnamaria FioreAntonio Ruiz-PorrasBratu (Simionescu) MihaelaB M SantoshArmin J. KAMMELSahar BahmaniEwa KleczykEyup DOGANFahmi Shaaban FararahHengky, S. HJudy LiPiotr SiemiątkowskiSaid jaouadiSakarnehSarker
Reviewer Acknowledgements
Authors: Young Daisy 
Published: January 2017

Business and Economic Research (BER) would like to thank the following reviewers for reviewing manuscripts from June 1, 2014, to December 1, 2014. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether IJSSS publishes their work, appreciate the helpful feedback provided by the reviewers. Macrothink Publishing appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period. Antonio Ruiz-PorrasBratu (Simionescu) MihaelaCosimo MagazzinoDavide ScaltritoEddie John FisherEwa KleczykHengky Sumisto HalimMohammad Nurul HudaOlubukunola Ranti UwuigbePiotr SiemiątkowskiRenata KorsakieneSahar BahmaniSaid JaouadiSantosh Banadahally ManjegowdaSocrates O. BallaisUwalomwa Uwuigbe