bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of environmental conditions on the seasonal and inter‐annual variability of small pelagic fish abundance off North‐West Africa: The case of both Senegalese sardinella
Authors: Thiaw Modou , Auger Pierre‐Amaël , Ngom Fambaye , Brochier Timothée , Faye Saliou , Diankha Ousmane , Brehmer Patrice 
Published: May 2017

AbstractThe objective of this study was to assess the effect of environmental variations on the abundance of Sardinella aurita and Sardinella maderensis in Senegalese waters in the upwelling system. Monthly data indicating the abundance of sardinella were first estimated from commercial statistics, using Generalized Linear Model from 1966 to 2011. Abundance indices (AIs) were then compared with environmental indices, at the local scale, a Coastal Upwelling Index (CUI) and a coastal Sea Surface Temperature (SST) index, and on a large scale, the North Atlantic Oscillation (NAO), the Atlantic Multidecadal Oscillation (AMO) and the Multivariate El Niño Southern Oscillation Index (MEI), using correlations and times series analyses. The results showed that the abundance of sardinella is determined by a strong seasonal pattern and inter‐annual fluctuations. The abundance of S. aurita peaked in spring and in autumn, whereas that of S. maderensis peaked in the warm season (July–September). The trend of the sardinella abundance was significantly correlated with the CUI, especially in autumn and spring. Interannual fluctuations of S. maderensis and S. aurita abundance are, respectively, driven by the precocity and the duration of the upwelling season that is attributed to distinct migration patterns. Both sardinella species also respond with a delay of around 4 years to the winter NAO index and the autumn CUI, and the AMO index, respectively, both related to migration patterns. The wide variations in sardinella biomass are caused by variations in environmental conditions, which should be considered in the implementation of an ecosystem‐based approach in sardinella stocks management.
Comparison of F13A1 gene mutations in 73 patients treated with recombinant FXIII‐A2
Authors: Ivaškevičius V. , Biswas A. , Garly M.‐L. , Oldenburg J. 
Published: May 2017

IntroductionCongenital factor XIII (FXIII) deficiency is a rare, autosomal recessive bleeding disorder usually caused by mutations in the F13A1 gene that produce a severe quantitative (type I) deficiency of the FXIII‐A subunit.AimTo determine the genotypes of patients with severe FXIII‐A deficiency treated with recombinant FXIII‐A subunit (rFXIII‐A2) participating in three international efficacy and safety trials.MethodsWe determined the genotypes of 73 patients in total; 32 had already undergone genotype analysis and were known to carry F13A1 mutations that have been previously reported in the literature. Mutation screening was performed in 41 patients with unknown genetic status using direct sequencing.ResultsIn total, 51 distinct mutations in 73 patients were identified. Two patients showed a phenotype of severe FXIII‐A deficiency, despite having heterozygous missense mutations. Two siblings carried a missense mutation in the F13A1 gene (p.Ser296Arg) in combination with a novel, probably polymorphic variant of the F13B gene (p.Ser654Phe). Molecular modelling of five F13A1 novel missense mutations (p.Leu171Phe, p.Glu204Lys, p.Leu276Phe, p.Asp405His and p.Gly411Cys) predicted a damaging effect of these mutations on protein structure. Although five patients treated with rFXIII‐A2 had transient, low‐titre, non‐neutralizing anti‐rFXIII antibodies, no patients developed FXIII‐neutralizing antibodies (inhibitors).ConclusionThe identified mutations are causally implicated in severe FXIII deficiency; however, they do not appear to increase the risk of neutralizing antibody development against rFXIII‐A2.
An Evaluation of Oral Presentation Competency in Interior Design Education
Authors: Hynes Wendy , Kwon Hyun Joo 
Published: May 2017

AbstractAs digital modelling programmes become increasingly prevalent in interior design education, there is concern that graduates are entering the workforce relying too much on strong graphic presentation skills while lacking the basic ability to speak about design. This study explores the gap between practitioners’ perceptions of importance regarding oral presentation competency and students’ perceptions of their oral presentation performances. Additionally, the study explores correlations between in‐class activities and students’ perceptions of their oral presentation competency. Mixed‐methods of investigation include a Delphi study with a panel of interior design practitioners and a survey questionnaire of both practitioners (n = 102) and currently active interior design students (n = 91) in the USA. An Importance‐Performance framework is employed for comparison. Results identify performance criteria for evaluating oral presentation competency and indicate variances between students’ perceptions of their performance and industry perceptions of importance. Furthermore, students’ in‐class activities including studio critiques and written peer assessments show significant correlation with student oral presentation performance indicating activities already frequently incorporated into a design curriculum may have a greater impact on improving performance than specific oral presentation instruction alone.
Telemedicine in dermatology: findings and experiences worldwide – a systematic literature review
Authors: Trettel A. , Eissing L. , Augustin M. 
Published: May 2017

AbstractTelemedicine has become an important element of health care in many countries and profited from the technological progress of the last two decades. Due to the visual character of the dermatological specialty, teledermatology in particular participated in that development and is becoming a major tool in dermatological consultation. The objective of this article was to identify the use of teledermatology across the world based on published original articles. A systematic literature search of the MEDLINE and Embase databases for eligible publications (predefined inclusion and exclusion criteria) and a cross‐validation search were conducted. Search results were reviewed systematically. The search resulted in 204 publications meeting the inclusion criteria for analysis. The highest number of published studies on teledermatology was performed in the United States, followed by the United Kingdom, Spain, the Netherlands, Italy and Austria. The majority of dermatological indications for telemedical consultations were not specified or included various kinds of skin diseases, followed by skin cancer and wounds. Research questions predominantly focused on concordance, effectiveness and cost‐effectiveness to determine the value. Teledermatology proved to be a reliable consultation tool in the majority of studies. If specified, telemedicine was used in daily dermatological routine for patient management purposes, to consult patients in peripheral locations, or for medical support in nursing homes or home care settings. The application of teledermatology worldwide is highest in North American and European countries, while countries with poor geographical distribution of physicians seem to be under‐represented in teledermatological use, as concluded from publication output. Regarding indications, comparison with classic consultation and area of application, most studies were of general nature. For precise determination of the value, systematic studies would be needed. However, teledermatology is already accepted as a valid tool.
Volver a Nuestras Raíces: The Reemergence and Adaptation of Traditional Forms of Andean Reciprocity
Authors: Lyle Henry F. 
Published: May 2017

ResumenEste manuscrito es inspirado por la investigación etnográfica del mantenimiento de las instituciones de propiedad común y redes de apoyo social en una pequeña comunidad quechua en el altiplano en el sur de Perú. Campesinos deben instituir los programas de cría y plantar y cultivar cosechas y otros trabajos de mantenimiento. Además de la acción colectiva, la mayoría de las casas tienen su propio jardín y rebaño que requieren el apoyo de otros hogares. El uso de la teoría del capital simbólico y modelos de castigo indirecto, explico cómo formas modificadas de ayni y minga trabajan en conjunto para resolver el problema de parasitismo en una pequeña comunidad de pastores de los Andes. En la exploración de esta intersección convincente de grupo y la cooperación diádica, describiré la acción colectiva y redes de apoyo social en la comunidad, y consideraré sus paralelismos con la reciprocidad andina tradicional. [Andes, ecologia, Peru]
Computed tomography or necropsy diagnosis of multiple bullae and the treatment of pneumothorax in rhesus macaques (Macaca mulatta)
Authors: Kim Jong‐Min , Han Sungyoung , Shin Jun‐Seop , Min Byoung‐Hoon , Jeong Won Young , Lee Ga Eul , Kim Min Sun , Kim Ju Eun , Chung Hyunwoo , Park Chung‐Gyu 
Published: May 2017

AbstractPulmonary bullae and pneumothorax have various etiologies in veterinary medicine. We diagnosed multiple pulmonary bullae combined with or without pneumothorax by computed tomography (CT) or necropsy in seven rhesus macaques (Macaca mulatta) imported from China. Two of seven rhesus macaques accompanied by pneumothorax were cured by fixation of ruptured lung through left or right 3rd intercostal thoracotomy. Pneumonyssus simicola, one of the etiologies of pulmonary bullae, was not detected from tracheobronchiolar lavage. To the best of our knowledge, this is the first case report on the CT‐aided diagnosis of pulmonary bullae and the successful treatment of combined pneumothorax by thoracotomy in non‐human primates (NHPs).
Identification of potential crucial genes associated with early‐onset pre‐eclampsia via a microarray analysis
Authors: Ma Yifei , Lin Hongmei , Zhang Hong , Song Xiu'e , Yang Huili 
Published: May 2017

AbstractAimThis study aimed to identify potential key genes related to early‐onset pre‐eclampsia (EOPET), and to obtain a better understanding of the molecular mechanisms of this disease.MethodsThe microarray dataset GSE44711 was obtained from the Gene Expression Omnibus, including eight chorionic villi samples from EOPET placentas and eight normal controls. The differentially expressed genes (DEG) were identified using the LIMMA package, and their potential functions were predicted by Gene Ontology (GO) enrichment analysis. Furthermore, protein–protein interactions (PPI) were obtained from the STRING database, and the PPI network was visualized by Cytoscape software. Then, significant modules were screened out from the PPI network, and GO enrichment analysis for DEG in modules was performed. Also, the potential transcription factors (TF) regulating DEG in modules were predicted, and TF–DEG network was visualized by Cytoscape.ResultsA total of 270 upregulated and 200 downregulated DEG were identified. A set of DEG was related to functions such as female pregnancy and hormone metabolic process (e.g. NGF). In PPI network modules, some DEG (e.g. SERPINE1 and FN1) were significantly associated with anatomical structure morphogenesis, and some other DEG (e.g. GZMA) were relevant to the immune system process. Furthermore, SERPINE1, NGF, and FN1 interacted with each other and were regulated by RELA.ConclusionThe DEG related to hormone metabolic process (e.g. NGF), anatomical structure morphogenesis (e.g. SERPINE1 and FN1), and immune system process (e.g. GZMA) are predicted to play significant roles in the progress of EOPET, which will be confirmed by experiments in future.
The Interface of Explicit and Implicit Knowledge in a Second Language: Insights From Individual Differences in Cognitive Aptitudes
Authors: Suzuki Yuichi , DeKeyser Robert 
Published: May 2017

AbstractRecent research has called for the use of fine‐grained measures that distinguish implicit knowledge from automatized explicit knowledge. In the current study, such measures were used to determine how the two systems interact in a naturalistic second language (L2) acquisition context. One hundred advanced L2 speakers of Japanese living in Japan were assessed using tests of automatized explicit knowledge and implicit knowledge, along with tests of phonological short‐term memory and aptitude tests for explicit and implicit learning. Structural equation modeling demonstrated that aptitude for explicit learning significantly predicted acquisition of automatized explicit knowledge, and automatized explicit knowledge significantly predicted acquisition of implicit knowledge. The effects of implicit learning aptitude and phonological short‐term memory on acquisition of automatized explicit knowledge and implicit knowledge were limited. These findings provide the first empirical evidence that automatized explicit knowledge, which develops through explicit learning mechanisms, may impact the acquisition of implicit knowledge.Open PracticesThis article has been awarded an Open Materials badge. All original materials are publicly accessible in the IRIS digital repository at http://www.iris-database.org. Learn more about the Open Practices badges from the Center for Open Science: https://osf.io/tvyxz/wiki.
A cryptic pigment biosynthetic pathway uncovered by heterologous expression is essential for conidial development in Pestalotiopsis fici
Authors: Zhang Peng , Wang Xiuna , Fan Aili , Zheng Yanjing , Liu Xingzhong , Wang Shihua , Zou Huixi , Oakley Berl R. , Keller Nancy P. , Yin Wen‐Bing 
Published: May 2017

SummarySpore pigmentation is very common in the fungal kingdom. The best studied pigment in fungi is melanin which coats the surface of single cell spores. What and how pigments function in a fungal species with multiple cell conidia is poorly understood. Here, we identified and deleted a polyketide synthase (PKS) gene PfmaE and showed that it is essential for multicellular conidial pigmentation and development in a plant endophytic fungus, Pestalotiopsis fici. To further characterize the melanin pathway, we utilized an advanced Aspergillus nidulans heterologous system for the expression of the PKS PfmaE and the Pfma gene cluster. By structural elucidation of the pathway metabolite scytalone in A. nidulans, we provided chemical evidence that the Pfma cluster synthesizes DHN melanin. Combining genetic deletion and combinatorial gene expression of Pfma cluster genes, we determined that the putative reductase PfmaG and the PKS are sufficient for the synthesis of scytalone. Feeding scytalone back to the P. fici ΔPfmaE mutant restored pigmentation and multicellular adherence of the conidia. These results cement a growing understanding that pigments are essential not simply for protection of spores from biotic and abiotic stresses but also for spore structural development.
T‐cells and macrophages peak weeks after experimental stroke: Spatial and temporal characteristics
Authors: Vindegaard Nina , Muñoz‐Briones Clara , El Ali Henrik H. , Kristensen Lotte Kellemann , Rasmussen Rune Skovgaard , Johansen Flemming Fryd , Hasseldam Henrik 
Published: May 2017

The activities of the central and peripheral immune systems impact neurological outcome after ischemic stroke. However, studies investigating the temporal profile of leukocyte infiltration, especially T‐cell recruitment, are sparse. Our aim was to investigate leukocyte infiltration at different time points after experimental stroke in mice. Permanent middle cerebral artery occlusion was performed on 11 weeks old C57BL/6J mice, allowed to survive for 1, 3, 8, 14 or 28 days. In addition to infarct size measurements, detailed immunohistochemical analyses of T‐cell and macrophage influx were performed. A recently introduced F‐19 MR probe (V‐sense), designed to track macrophages, was furthermore tested. Fourteen and 28 days after permanent middle cerebral artery occlusion a significant increase in CD3+ T‐cells was found within the ipsilateral hemisphere compared to controls, especially within the infarct core and the corpus callosum. The number of CD68+ cells within the infarct core was significantly increased at days 8, 14 and 28. This temporal pattern was also seen in MRI. After experimental stroke within the infarcted cortex we found a delayed (day 14) infiltration of T‐cells and macrophages. Furthermore, our data show that T‐cells are present in higher numbers in the corpus callosum compared to the rest of the brain (except from the infarct core where they were highest).
Co‐introduction vs ecological fitting as pathways to the establishment of effective mutualisms during biological invasions
Authors: Le Roux Johannes J. , Hui Cang , Keet Jan‐Hendrik , Ellis Allan G. 
Published: May 2017

SummaryInteractions between non‐native plants and their mutualists are often disrupted upon introduction to new environments. Using legume–rhizobium mutualistic interactions as an example, we discuss two pathways that can influence symbiotic associations in such situations: co‐introduction of coevolved rhizobia; and utilization of, and adaptation to, resident rhizobia, hereafter referred to as ‘ecological fitting’. Co‐introduction and ecological fitting have distinct implications for successful legume invasions and their impacts. Under ecological fitting, initial impacts may be less severe and will accrue over longer periods as novel symbiotic associations and/or adaptations may require fine‐tuning over time. Co‐introduction will have more profound impacts that will accrue more rapidly as a result of positive feedbacks between densities of non‐native rhizobia and their coevolved host plants, in turn enhancing competition between native and non‐native rhizobia. Co‐introduction can further impact invasion outcomes by the exchange of genetic material between native and non‐native rhizobia, potentially resulting in decreased fitness of native legumes. A better understanding of the roles of these two pathways in the invasion dynamics of non‐native legumes is much needed, and we highlight some of the exciting research avenues it presents.

Contents

Summary
1354

I.
Introduction
1354

II.
Specificity and effectiveness of legume–rhizobium interactions and their impacts on non‐native legume establishment
1355

III.
Co‐introduction and ecological fitting: two pathways to establish legume–rhizobium interactions during biological invasions
1357

IV.
Consequences of co‐introduction of rhizobia and non‐native legumes for invasion impacts
1357

V.
Concluding remarks and future directions
1359

Acknowledgements
1359

References
1359
SET DOMAIN GROUP701 encodes a H3K4‐methytransferase and regulates multiple key processes of rice plant development
Authors: Liu Kunpeng , Yu Yu , Dong Aiwu , Shen Wen‐Hui 
Published: May 2017

Summary

Chromatin‐based epigenetic information plays an important role in developmental gene regulation, in response to environment, and in natural variation of gene expression levels. Histone H3 lysine 4 di/trimethylation (H3K4me2/3) is abundant in euchromatin and is generally associated with transcriptional activation. Strikingly, however, enzymes catalyzing H3K4me2/3 remain poorly characterized in crops so far.

Here, we investigated the function of the rice SET DOMAIN GROUP 701 (SDG701) gene by molecular and biochemical characterization of the gene product, and by studying effects of its loss or gain of function on plant growth and development.

We demonstrated that SDG701 encodes a methytransferase specifically catalyzing H3K4 methylation. Overexpression and knockdown experiments showed that SDG701 is crucial for proper sporophytic plant development as well as for gametophytic transmission that directly impacts rice grain production. In‐depth analysis of plant flowering time revealed that SDG701 promotes rice flowering under either long‐day or short‐day photoperiods. Consistently, the SDG701 protein was found to bind chromatin to promote H3K4me3 and to enhance expression of the rice Hd3a and RFT1 florigens.

Collectively, our results establish SDG701 as a major rice H3K4‐specific methyltransferase and provide important insights into function of H3K4me3 deposition in transcription activation of florigens in promoting plant flowering.
Herbivory‐induced jasmonates constrain plant sugar accumulation and growth by antagonizing gibberellin signaling and not by promoting secondary metabolite production
Authors: Machado Ricardo A. R. , Baldwin Ian T. , Erb Matthias 
Published: May 2017

Summary

Plants respond to herbivory by reconfiguring hormonal networks, increasing secondary metabolite production and decreasing growth. Furthermore, some plants display a decrease in leaf energy reserves in the form of soluble sugars and starch, leading to the hypothesis that herbivory‐induced secondary metabolite production and growth reduction may be linked through a carbohydrate‐based resource trade‐off.

In order to test the above hypothesis, we measured leaf carbohydrates and plant growth in seven genetically engineered Nicotiana attenuata genotypes that are deficient in one or several major herbivore‐induced, jasmonate‐dependent defensive secondary metabolites and proteins. Furthermore, we manipulated gibberellin and jasmonate signaling, and quantified the impact of these phytohormones on secondary metabolite production, sugar accumulation and growth.

Simulated herbivore attack by Manduca sexta specifically reduced leaf sugar concentrations and growth in a jasmonate‐dependent manner. These effects were similar or even stronger in defenseless genotypes with intact jasmonate signaling. Gibberellin complementation rescued carbohydrate accumulation and growth in induced plants without impairing the induction of defensive secondary metabolites.

These results are consistent with a hormonal antagonism model rather than a resource–cost model to explain the negative relationship between herbivory‐induced defenses, leaf energy reserves and growth.
Legal Power: The Basic Definition
Authors: Lindahl Lars , Reidhav David 
Published: May 2017

AbstractThe concept of legal power (often called legal competence) is important in the law since, with regard to actions having legal effect, the “exercise of legal power” delimits those actions for which manifestation of intention to achieve a legal effect is essential for the effect to ensue. The paper proposes a definition that captures this feature of legal power and marks it off from “direct effect,” as well as from permissibility and practical ability to achieve the legal effect. This analysis of power is limited to the “immediate” legal power of a physical person characterized by the power‐holder achieving a legal result by the power‐holder's own behaviour (not by representatives acting on behalf of the power‐holder). It is argued that in the literature on power the concept of legal power is frequently construed in such a way that it becomes either too broad or too narrow.