bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress-Dilatancy for Soils. Part I: The Frictional State Theory
Authors: Szypcio Zenon 
Published: February 2017

Abstract
An unconventional subdivision of volumetric strains, the newly formulated frictional and critical frictional states and some of energetic and stress condition assumptions result in new stress-plastic dilatancy relationships. These new stress-plastic dilatancy relationships are functions of the deformation mode and drainage conditions. The critical frictional state presented in this paper is a special case of the classical critical state.
Synthesis and characterization of the alkali borate-nitrates Na3–x
K
x
[B6O10]NO3 (x=0.5, 0.6, 0.7)
Authors: Ortner Teresa S. , Schildhammer Daniel , Tribus Martina , Joachim Bastian , Huppertz Hubert 
Published: February 2017

Abstract
Three novel mixed alkali borate-nitrates Na3−x
K
x
[B6O10]NO3 (x=0.5, 0.6, 0.7) were synthesized hydrothermally; their crystal structures were determined through Rietveld analyses, and supported through EDX as well as vibrational spectroscopy. The phases represent solid solutions of the alkali borate-nitrate Na3(NO3)[B6O10], which was reported in 2002 as a “New type of boron-oxygen framework in the Na3(NO3)[B6O10] crystal structure” (O. V. Yakubovich, I. V. Perevoznikova, O. V. Dimitrova, V. S. Urusov, Dokl. Phys.
2002, 47, 791). Only two of the three crystallographically independent Na+ positions in the new structures are partially substituted by K+; a pure potassium borate-nitrate was not formed until now. The cell parameters of the novel phases vary from a=1261.72(5)–1267.12(5), b=1004.19(5)–1007.96(4), c=770.55(3)–774.38(3) pm, and V=0.97630(6)–0.98905(6) nm3 in the orthorhombic space group Pnma (no. 62), in alignment with increasing K+ content.
Dysregulated Glycine Signaling Contributes to Increased Impulsivity during Protracted Alcohol Abstinence
Authors: Irimia Cristina , Buczynski Matthew W. , Natividad Luis A. , Laredo Sarah A. , Avalos Nathaniel , Parsons Loren H. 
Published: February 2017

Persons with alcoholism who are abstinent exhibit persistent impairments in the capacity for response inhibition, and this form of impulsivity is significantly associated with heightened relapse risk. Brain-imaging studies implicate aberrant prefrontal cortical function in this behavioral pathology, although the underlying mechanisms are not understood. Here we present evidence that deficient activation of glycine and serine release in the ventral medial prefrontal cortex (vmPFC) contributes to increased motor impulsivity during protracted abstinence from long-term alcohol exposure. Levels of 12 neurotransmitters were monitored in the rat vmPFC during the performance of a challenging variant of the five-choice serial reaction time task (5-CSRTT) in which alcohol-exposed rats exhibit excessive premature responding. Following long-term ethanol exposure, rats showed blunted task-related recruitment of vmPFC glycine and serine release, and the loss of an inverse relationship between levels of these neurotransmitters and premature responding normally evident in alcohol-naive subjects. Intra-vmPFC administration of the glycine transport inhibitor ALX5407 prevented excessive premature responding by alcohol-exposed rats, and this was reliant on NMDA glycine site availability. Alcohol-exposed rats and controls did not differ in their premature responding and glycine and serine levels in vmPFC during the performance of the standard 5-CSRTT. Collectively, these findings provide novel insight into cortical neurochemical mechanisms contributing to increased impulsivity following long-term alcohol exposure and highlight the NMDA receptor coagonist site as a potential therapeutic target for increased impulsivity that may contribute to relapse risk.SIGNIFICANCE STATEMENTPersons with alcoholism demonstrate increased motor impulsivity during abstinence; however, the neuronal mechanisms underlying these behavioral effects remain unknown. Here, we took advantage of an animal model that shows deficiencies in inhibitory control following prolonged alcohol exposure to investigate the neurotransmitters that are potentially responsible for dysregulated motor impulsivity following long-term alcohol exposure. We found that increased motor impulsivity is associated with reduced recruitment of glycine and serine neurotransmitters in the ventromedial prefrontal cortex (vmPFC) cortex in rats following long-term alcohol exposure. Administration of glycine transport inhibitor ALX5407 in the vmPFC alleviated deficits in impulse control.
Takotsubo cardiomyopathy in amiodarone-induced hyperthyroidism
Authors: Capel Ismael , Tasa-Vinyals Elisabet , Cano-Palomares Albert , Bergés-Raso Irene , Albert Lara , Rigla Mercedes , Caixàs Assumpta 
Published: February 2017

Summary
Takotsubo cardiomyopathy (TC) is an atypical, severe but reversible form of acute heart insufficiency. It typically presents with left ventricular failure, transient apical and mid-segments hypokinesis, absence of significant coronary stenosis and new electrographic abnormalities and/or elevation in serum cardiac enzymes. Although TC (‘broken heart syndrome’) has classically been associated with emotional trauma, evidence suggests that other precipitants might exist, including iatrogenic and thyroid-mediated forms. Thyroid disease is a relatively common comorbidity in TC patients. We report a case of TC in a postmenopausal female with no history of emotional trauma or other potential precipitant factors who was diagnosed with amiodarone-induced hyperthyroidism during her hospital stay. Though some case reports of thyroid-related TC exist, we are not aware of any other reported case of TC precipitated by amiodarone-induced hyperthyroidism.

Learning points:

TC is a relatively new, rare, transient, severe, but reversible cardiovascular condition that is characterized by an acute left ventricular cardiac failure, which can clinically, analytically and electrocardiographically mimic an acute myocardial infarction.

Many precipitant factors have been described in TC, being the most classical and emotional trauma. However, thyroid dysfunction is also a significant condition frequently found in patients with TC.

A hypercatecholaminergic state leading to cardiomyocyte damage has been established as the main fact of TC physiopathology. Hyperthyroidism induces an upregulation of β-adrenergic receptors.

Both hyperthyroidism and hypothyroidism have been related with TC development. Most reported cases of TC involving thyroid dysfunction correspond to hyperthyroidism due to Graves–Basedow disease, but there are also descriptions with severe hypothyroidism, radioiodine treatment or thyroid surgery.

Amiodarone is a class III antiarrhythmic agent widely used, and it is a well-known cause of thyroid dysfunction, which can present either with hypothyroidism or hyperthyroidism, as approximately 40 percent of the amiodarone molecule is composed of iodine.

In this case, a type II amiodarone-induced hyperthyroidism was the precipitant factor of a TC in a patient with a pre-existing atrial fibrillation. Given the high prevalence of atrial fibrillation and the wide use of amiodarone, the risk of this iatrogenic effect should be taken into account.
Octreotide therapy and restricted fetal growth: pregnancy in familial hyperinsulinemic hypoglycemia
Authors: Geilswijk Marianne , Andersen Lise Lotte , Frost Morten , Brusgaard Klaus , Beck-Nielsen Henning , Frederiksen Anja Lisbeth , Jensen Dorte Møller 
Published: February 2017

Summary
Hypoglycemia during pregnancy can have serious health implications for both mother and fetus. Although not generally recommended in pregnancy, synthetic somatostatin analogues are used for the management of blood glucose levels in expectant hyperinsulinemic mothers. Recent reports suggest that octreotide treatment in pregnancy, as well as hypoglycemia in itself, may pose a risk of fetal growth restriction. During pregnancy, management of blood glucose levels in familial hyperinsulinemic hypoglycemia thus forms a medical dilemma. We report on pregnancy outcomes in a woman with symptomatic familial hyperinsulinemic hypoglycemia, type 3. During the patient’s first pregnancy with a viable fetus octreotide treatment was instituted in gestational age 23 weeks to prevent severe hypoglycemic incidences. Fetal growth velocity declined, and at 37 weeks of gestation, intrauterine growth retardation was evident. During the second pregnancy with a viable fetus, blood glucose levels were managed through dietary intervention alone. Thus, the patient was advised to take small but frequent meals high in fiber and low in carbohydrates. Throughout pregnancy, no incidences of severe hypoglycemia occurred and fetal growth velocity was normal. We conclude that octreotide treatment during pregnancy may pose a risk of fetal growth restriction and warrants careful consideration. In some cases of familial hyperinsulinemic hypoglycemia, blood glucose levels can be successfully managed through diet only, also during pregnancy.

Learning points:

Gain-of-function mutations in GCK cause familial hyperinsulinemic hypoglycemia.

Hypoglycemia during pregnancy may have serious health implications for mother and fetus.

Pregnancy with hyperinsulinism represents a medical dilemma as hypoglycemia as well as octreotide treatment may pose a risk of fetal growth restriction.

In some cases of familial hyperinsulinemic hypoglycemia, blood glucose levels can be successfully managed through diet only.
Project IMPACT Pilot Report: Feasibility of Implementing a Hospital-to-Home Transition Bundle
Authors: Mallory Leah A. , Osorio Snezana Nena , Prato B. Stephen , DiPace Jennifer , Schmutter Lisa , Soung Paula , Rogers Amanda , Woodall William J. , Burley Kayla , Gage Sandra , Cooperberg David ,   IMPACT Pilot Study Group
Published: February 2017

BACKGROUND AND OBJECTIVES:To improve hospital to home transitions, a 4-element pediatric patient-centered transition bundle was developed, including: a transition readiness checklist; predischarge teach-back education; timely and complete written handoff to the primary care provider; and a postdischarge phone call. The objective of this study was to demonstrate the feasibility of bundle implementation and report initial outcomes at 4 pilot sites. Outcome measures included postdischarge caregiver ability to teach-back key home management information and 30-day reuse rates.METHODS:A multisite, observational time series using multiple planned sequential interventions to implement bundle components with non–technology-supported and technology-supported patients. Data were collected via electronic health record reviews and during postdischarge phone calls. Statistical process control charts were used to assess outcomes.RESULTS:Four pilot sites implemented the bundle between January 2014 and May 2015 for 2601 patients, of whom 1394 had postdischarge telephone encounters. Improvement was noted in the implementation of all bundle elements with the transitions readiness checklist posing the greatest feasibility challenge. Phone contact connection rates were 69%. Caregiver ability to teach-back essential home management information postdischarge improved from 18% to 82%. No improvement was noted in reuse rates, which differed dramatically between technology-supported and non–technology-supported patients.CONCLUSIONS:A pediatric care transition bundle was successfully tested and implemented, as demonstrated by improvement in all process measures, as well as caregiver home management skills. Important considerations for successful implementation and evaluation of the discharge bundle include the role of local context, electronic health record integration, and subgroup analysis for technology-supported patients.
Respiratory Morbidity in Infants Born With a Congenital Lung Malformation
Authors: Delestrain Celine , Khen-Dunlop Naziha , Hadchouel Alice , Cros Pierrick , Ducoin Héloïse , Fayon Michael , Gibertini Isabelle , Labbé André , Labouret Géraldine , Lebras Marie-Noëlle , Lezmi Guillaume , Madhi Fouad , Thouvenin Guillaume , Thumerelle Caroline , Delacourt Christophe 
Published: February 2017

BACKGROUND AND OBJECTIVES:
The actual frequency of respiratory symptoms related to congenital pulmonary malformations (CPMs) remains undetermined. The goal of this study was to prospectively evaluate the respiratory symptoms occurring in infants with prenatally diagnosed CPMs, identify factors associated with the occurrence of these symptoms, and evaluate their resolution after surgery.

METHODS:
Infectious and noninfectious respiratory symptoms were prospectively collected in a French multicenter cohort of children with CPMs.

RESULTS:
Eighty-five children were followed up to the mean age of 2.1 ± 0.4 years. Six children (7%) underwent surgery during the first 28 days of life. Of the 79 remaining children, 33 (42%) had respiratory symptoms during infancy before any surgery. Wheezing was the dominant symptom (24 of 79 [30%]), and only 1 infant had documented infection of the cystic lobe. Symptoms were more frequent in children with noncystic CPMs, prenatally (P = .01) or postnatally (P &lt; .03), and with postnatally hyperlucent CPMs (P &lt; .01). Sixty-six children underwent surgery during the follow-up period, and 40% of them displayed symptoms after the intervention. Six children had documented pneumonia during the postoperative period. At the end of the follow-up, pectus excavatum was observed in 10 children, significantly associated with thoracotomy (P &lt; .02) or with surgery before the age of 6 months (P &lt; .002).

CONCLUSIONS:
CPMs are frequently associated with wheezing episodes. Surgery had no significant impact on these symptoms but was associated with a paradoxical increase in pulmonary infections, as well as an increased risk of pectus excavatum after thoracotomy.
A DFT study on Dichloro{(E)-4-dimethylamino-N′-[(pyridin-2 yl)methylidene-κN]benzohydrazide-κO}M2+ (M=Zn, Cu, Ni and Co) complexes: Effect of the metal over association energy and complex geometry
Authors: Gordillo Varela Mónica Andrea , Gutiérrez Gómez Gustavo Adolfo , Chaur Valencia Manuel Noé 
Published: February 2017

La geometría molecular de la (E)-4-dimetilamino-N′-[(piridin-2-il)metilideno- N]benzohidrazida (C15H16N4O) acomplejada con iones M2+ (M=Zn, Cu, Ni, Fe, Mn, Ca y Co) se calculó usando la teoría funcional de densidad (B3LYP) empleando un conjunto de bases 6-31G(d, p). Las frecuencias vibracionales fueron calculadas con el propósito de comprobar la ausencia de frecuencias vibracionales imaginarias, hecho que confirma el mínimo global en la optimización de la geometría. Los parámetros de la geometría molecular (longitudes de enlace y ángulos) para los complejos de Cu2+ y Zn2+ fueron comparados con datos cristalográficos previamente reportados, mostrando una buena correlación. Las energías de asociación para todos los complejos fueron determinadas a un nivel de teoría B3LYP/6-31G++(d, p) mostrando que el complejo menos favorable es Cu-L, correspondiente al catión más pequeño del estudio. Por otro lado Ca-L, uno de los menos estables, corresponde al catión más grande analizado. Se llevó a cabo un análisis de orbitales moleculares en el cual los complejos exhibieron diferentes valores de diferencia de energía HOMO-LUMO en función del metal empleado.
Síntesis y caracterización estructural de hidrotalcitas de Cu-Zn-Al
Authors: Meza Fuentes Edgardo , Rodríguez Ruiz Johana , Pájaro Payares Adolfo 
Published: February 2017

Las hidrotalcitas pueden ser usadas en áreas como catálisis, medicina, química ambiental, entre otras. Dependiendo de los metales presentes, los sólidos derivados de la calcinación de hidrotalcitas también son usados debido a su carácter básico, efecto de memoria y alta área superficial especifica. En este estudio se evaluaron características de hidrotalcitas a base de Cu-Zn-Al. Los análisis se realizaron usando AAS, DRX, FTIR, TGA y DSC. Se observó que, en los sólidos con mayor cantidad de cobre, la banda del estiramiento O••H (M••OH, H••OH) se desplaza a valores más bajos de número de onda, debido a que la densidad electrónica de los grupos OH se orienta hacia el centro metálico de cobre. En todos los sólidos se observó la formación de la fase hidrotalcita, y de la fase Cu(OH)2 en los sólidos con mayor contenido de cobre, lo que puede ser atribuido al efecto Jahn-Teller. Los resultados mostraron que los sólidos con mayor contenido de cobre colapsan en temperaturas menores. En todas las muestras se observaron eventos como: descomposición de la estructura HTLc, formación de óxidos metálicos y descomposición de carbonatos que quedaron ocluidos en los poros de los sólidos debido al colapso de la estructura laminar.
Gambling disorder-related illegal acts: Regression model of associated factors
Authors: Gorsane Mohamed Ali , Reynaud Michel , Vénisse Jean-Luc , Legauffre Cindy , Valleur Marc , Magalon David , Fatséas Mélina , Chéreau-Boudet Isabelle , Guilleux Alice , JEU Group  , Challet-Bouju Gaëlle , Grall-Bronnec Marie 
Published: February 2017

Background and aims
Gambling disorder-related illegal acts (GDRIA) are often crucial events for gamblers and/or their entourage. This study was designed to determine the predictive factors of GDRIA.

Methods
Participants were 372 gamblers reporting at least three DSM-IV-TR (American Psychiatric Association, 2000) criteria. They were assessed on the basis of sociodemographic characteristics, gambling-related characteristics, their personality profile, and psychiatric comorbidities. A multiple logistic regression was performed to identify the relevant predictors of GDRIA and their relative contribution to the prediction of the presence of GDRIA.

Results
Multivariate analysis revealed a higher South Oaks Gambling Scale score, comorbid addictive disorders, and a lower level of income as GDRIA predictors.

Discussion and conclusion
An original finding of this study was that the comorbid addictive disorder effect might be mediated by a disinhibiting effect of stimulant substances on GDRIA. Further studies are necessary to replicate these results, especially in a longitudinal design, and to explore specific therapeutic interventions.
Trichophytie als Bestandsproblem in der Wahrnehmung praktizierender Tierärzte
Authors: Andres Tatjana , Exner Ulrike , Strie Regina , Kleen Joachim 
Published: February 2017

Zusammenfassung
Gegenstand und Ziel: Trichophytie wird in der Literatur als häufig vorkommende Erkrankung des Rindes beschrieben, tatsächlich erhobene Daten gibt es jedoch kaum. In Fallberichten wird die Erkrankung dagegen häufiger dargestellt. Wahrnehmung ist allerdings Voraussetzung für eine strategische Bekämpfung, die neben der Vakzination betriebliche Maßnahmen wie Reinigung und Desinfektion verlangt. Material und Methoden: Im Rahmen einer Fortbildungsveranstaltung wurden mit einem Fragebogen von 378 praktizierenden Tierärzten Einschätzungen zur Problematik der Trichophytie erhoben. Ergebnisse: Die überwiegende Mehrheit der Befragten war der Auffassung, dass Trichophytie als Bestandsproblem und Zoonose nicht ausreichend wahrgenommen wird, und gab an, die Erkrankung regelmäßig in Betrieben vorzufinden. Ebenso erklärte eine Mehrheit der Befragten, Trichophytie regelmäßig zu behandeln. Demgegenüber wurde die Wahrnehmung der Erkrankung in betroffenen Betrieben als unzureichend angesehen. Die Möglichkeit der Vakzination wurde durchgängig positiv bewertet. Schlussfolgerungen: Praktizierende Tierärzte nehmen Trichophytie als relevantes Problem der Tiergesundheit wahr. Hier besteht nach dem Urteil der Tierärzte ein Unterschied zu den betroffenen Betrieben selbst. Die Studie erlaubt die Schlussfolgerung, dass durch Aufklärungsmaßnahmen und gezielte Angebote Trichophytie in größerem Rahmen bekämpft werden könnte.
Nieprawidłowości w gospodarce finansowej jednostek samorządu terytorialnego ujawniane przez regionalne izby obrachunkowe – analiza za lata 2006–2014
Authors: Sołtyk Piotr 
Published: February 2017

The issue presented in the article refers to the disclosure of legal violations revealed by regional chambers of audit (RCA) as a result of financial audits of local government units. The article also assesses the financial implications of the various types of irregularities. Given the scale of the irregularities disclosed, the article addresses the concept of management control as a new category of financial goal. According to the assumptions of the legislature, this goal is to support the realisation of the aims and tasks of local government. Bearing in mind the desire to reduce risk factors generating the formation of irregularities, the article presents the essence of control mechanisms in the operation of financial management.The article presents the violations most frequently disclosed by the RCA as regards the operation of the financial management of local governments. It offers a review of the literature and examines RCA activity reports prepared by the National RCA Board. A secondary analysis of the legislation was also carried out. The study covers the years 2006–2014, a period that saw financial law change profoundly.
Wpływ promieniowania gamma na kondycję roślin zimozielonych na przykładzie żywotnika zachodniego (Thuja occidentalis)
Authors: Sarnek Maciej , Szopa Przemysław , Czerniak Jacek , Gajewski Andrzej 
Published: February 2017

The article examines the suitability of the American Arborvitae (Thuja occidentalis) as a biomarker in cases of chlorophyll contamination caused by gamma radiation. Prior to the analysis, the samples were irradiated by isotop 22Na. Following exposure, the samples were analysed with spectrofluorescence, during which fluorescence emission comes from the excitation of chlorophyll. Our results showed that gamma irradiation leads to a reduction in the chlorophyll content. Therefore Thuja occidentalis can be treated as a biomarker for gamma radiation.
Twilight
Authors: P Preethu 
Published: February 2017

'Twilight' is a poem about the identity crisis faced by an average Indian woman. Religious tradition speaks of her as Shakti ( goddess) who is the primordial cosmic energy representing the divine feminine. At the same time, she has to suffer a lot of atrocities in the patriarchal society, ranging from female infanticide to death. Juniper symbolises the journey in which selfhood is not compromised. In dreams of a glorious past, she chants the Sakti mantra (hymn) and invokes the goddess in the highest tip of the tree of selfhood while the cruel reality binds her to the roots.
LA REVOLUCIÓN CUBANA EN UN NUEVO CONTEXTO HISTÓRICO
Authors: Ríos Olga Fernández 
Published: February 2017

Se analizan importantes factores y contradicciones que influyen en el avance de la Revolución Cubana a partir de los acuerdos adoptados por el VI Congreso del Partido Comunista (PCC), celebrado en 2011. El Congreso ratificó la estrategia de desarrollo socialista y la implementación de un nuevo modelo de desarrollo económico y social que rompe con estructuras y prácticas estadocentristas que predominaron en el llamado “socialismo real”, y a la vez que ratificó la propiedad estatal sobre los más importantes medios de producción, amplío las formas no estatales de propiedad y gestión económica. Todo ello introduce cambios en la estructura socioclasista y en el modo de construir el socialismo, lo que genera nuevos desafíos para garantizar la continuidad de la transición socialista. Se trata de un nuevo contexto histórico en el que institucionalidad y participación popular deben fortalecerse para garantizar la permanente renovación de la hegemonía socialista.Palabras clave: Transición socialista, Sexto Congreso del PCC, modelos de desarrollo, neodesarrollismo, desafíos sociopolíticos