bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bloqueo auriculoventricular fetal completo: enfoque diagnóstico y terapéutico; reporte de caso en Bogotá, Colombia y revisión de la literatura
Authors: Poveda-Rojas Diana Cecilia , Vélez-Tirado Natalia , Bonilla-Cortes Leonardo , Rozo-Galindo Juan Pablo 
Published: December 2017

Objetivo: reportar un caso de bloqueo auriculoventricular completo congénito y realizar una revisión de la literatura del diagnóstico y tratamiento.Materiales y métodos: se reporta el caso de una gestante de 27 años quien consulta a un hospital general de alto nivel de complejidad, con un embarazo de 33 semanas, con feto único, con diagnóstico de bloqueo auriculoventricular completo y cardiomiopatía dilatada secundaria. Se inició manejo prenatal con betamimético con pobre respuesta, por lo cual fue necesario finalizar el embarazo. El recién nacido requiere implantación de marcapasos ventricular en el primer día de vida con excelentes resultados en el seguimiento a un año. Se realiza revisión de la literatura publicada en las bases de datos: Medline vía PubMed, Lilacs y SciELO mediante los términos: “fetal complete atrioventricular block”, “congenital complete heart block”, con límites de año de 2000 a 2016, en español e inglés.Resultados: se obtuvieron 21 publicaciones; siete reportes de caso, diez revisiones de literatura, cuatro estudios de cohorte. El diagnóstico se basa en la ecocardiografía fetal para determinar el intervalo PR, la relación auriculoventricular y la detección de anomalías intracardiacas, entre las que se encuentran: regurgitación valvular, hiperecogenicidad miocárdica/valvular-fibroelastosis endocárdica, contracciones atriales prematuras y efusión pericárdica. Respecto al tratamiento prenatal, los medicamentos más utilizados son los corticoesteroides y los betamiméticos. El tratamiento de la bradiarritimia severa refractaria neonatal puede requerir la implantación de un marcapaso como manejo definitivo.Conclusión: el bloqueo AV congénito de tercer grado requiere diagnóstico temprano y tratamiento oportuno, ya que se acompaña de alta morbimortalidad perinatal. Se requieren estudios con mayor calidad metodológica que permitan avalar otras opciones y esquemas terapéuticos prometedores.
A reinserção positiva de imigrantes refugiados sob o prisma das Nações Unidas com o aporte da Ciência Ontopsicológica: o desenvolvimento de uma oficina de integração social de imigrantes voltada ao público jovem
Authors: Rieder Daiane Dutra 
Published: December 2017

O presente trabalho tece uma pesquisa no âmbito dos Objetivos de Desenvolvimento Sustentáveis (ODS) da ONU – Organização das Nações Unidas, compreendido como tradução do real sentido de sustentabilidade. Neste escopo, aqui, serão relatadas experiências pertinentes à reinserção positiva de imigrantes e refugiados sobre o prisma das Nações Unidas e da Ciência Ontopsicológica, buscando-se ter como abrangência principal os Objetivos (ODS) 10 e 16 que dispõem, respectivamente, sobre: “Redução das desigualdades” e “Paz, justiça e instituições fortes”.Dentre os 17 objetivos e 169 metas a serem atingidas até 2030, foram escolhidos esses dois tópicos a serem relatados, devido sua contingência perante a real situação em que se encontram migrantes e refugiados internacionais como suscetíveis emblemas do corpo social. Tal temática norteia o contexto da vida que lhes é sucedida, bem como propõe soluções afins para os ditames da humanidade. Nesse âmbito, explanar-se-á o respaldo da situação “migrante” como sujeito de direitos e vítima do social, de modo a emergir a aplicação dos Objetivos de Desenvolvimento Sustentável como meio a proporcionar a sua reinserção positiva no local em que se aderem de maneira humanista.
Women, Midwives, and a Medical Model of Maternity Care in Switzerland
Authors: Brailey Sue , Luyben Ans , van Teijlingen Edwin , Frith Lucy 
Published: December 2017

This article presents a case study on the organization of maternity health care in Switzerland. Switzerland has a costly health care system with high intervention rates within an obstetric-led maternity care model. Evidence has shown that midwifery care is associated with lower cost, higher satisfaction rates among women, and less intervention. However, in this model, midwives are both marginalized and underused.The article focuses on the distribution of power and knowledge between midwives, women, and the medical profession. The varying power structures that shape the maternity care system in Switzerland are examined, using a case study approach that draws on Foucault’s concepts of the gaze, surveillance, disciplinary power, and the docile body. This article critically analyzes the model of maternity care received by women in Switzerland and how it negatively impacts on both women’s personal and midwives’ professional autonomy while simultaneously driving up costs.A better understanding of the underlying power structures operating within the maternity care system may facilitate the implementation of more midwifery-led care currently being endorsed by the Swiss Midwifery Association and some government agencies. This could result in reduced cost and lower intervention rates with reduced associated morbidity.
Keterampilan Menulis Karangan Narasi pada Anak Gifted with Disynchronous Development (Studi Tunggal pada Satu Subjek)
Authors: Wachidah Kemil 
Published: December 2017

This case study described twelve narrative essays of Miko within aspects of language, cognitive, and affective. Miko is Gifted child With Disynchronous Development. The results indicated that the narrative essays in aspects of language, cognitive, and affective, as follows: 1) organizing content according to the narrative structure that consists of five components, namely opening, inciting moment, development stage, denouement and ending; 2) choice of words (diction) that appear in the narrative essays are general and specific words, abstract, slang, foreign, and a figure of speech metaphor; 3) the sentences that appear in the narrative essays are simple sentence, compound sentence, and complex sentence; 4) tools of cohesion grammatical in the narrative essays are reference, substitution, ellipsis, and conjunction; and 5) specific style of spelling was found consistently in the narrative essays; 6) cognitive skill of Miko in the narrative essays is inference; and 7) affective skill of Miko are openness, sympathetic, gracious, and emphathetic in the narrative essays.
Omecamtiv Mecarbil: A Myosin Motor Activator Agent with Promising Clinical Performance and New in vitro Results
Authors: Nanasi Peter , Komaromi Istvan , Gaburjakova Marta , Almassy Janos 
Published: December 2017

Background:
Clinical treatment of heart failure is still suffering from limited efficacy
and unfavorable side effects. The recently developed group of agents, the myosin motor activators,
act directly on cardiac myosin resulting in an increased force generation and prolongation
of contraction. The lead molecule, omecamtiv mecarbil is now in human 3 stage. In addition to
the promising clinical data published so far, there are new in vitro results indicating that the effect
of omecamtiv mecarbil on contractility is rate-dependent. Furthermore, omecamtiv mecarbil
was shown to activate cardiac ryanodine receptors, an effect that may carry proarrhythmic risk.

Methods:
These new results, together with the controversial effects of the drug on cardiac oxygen
consumption, are critically discussed in this review in light of the current literature on omecamtiv
mecarbil.

Results:
In therapeutically relevant concentrations the beneficial inotropic effect of the agent is
not likely affected by these new results - in accordance with the good clinical data. At supratherapeutic
concentrations, however, activation of cardiac ryanodine receptors may increase
arrhythmia propensity, and the stronger effect on diastolic than systolic cell shortening, observed
at higher pacing frequencies, may decrease or offset the inotropic effect of omecamtiv
mecarbil.

Conclusion:
Further studies with definitely supratherapeutical concentrations of omecamtiv
mecarbil should be designed to map the actual risk of these potentially harmful side-effects.
Looking for New Antifungal Drugs from Flavonoids: Impact of the Genetic Diversity of Candida albicans on the in-vitro Response
Authors: Felice Maria Rosa , Giuffrè Letterio , El Aamri Lamya , Hafidi Majida , Criseo Giuseppe , Romeo Orazio , Scordino Fabio 
Published: December 2017

Background:In an era in which antimicrobial resistance is increasing at an alarming pace, it is very important to find new antimicrobial agents effective against pathogenic microrganisms resistant to traditional treatments. Among the notable breakthroughs in the past years of research in natural-drug discovery, there is the identification and testing of flavonoids, a group of plant-derived substances capable of promoting many beneficial effects on humans. These compounds show different biological activities such as inhibition of neuroinflammation and tumor growth as well as antimicrobial activity against many microbial pathogens.Methods:We undertook a review of protocols and standard strains used in studies reporting the inhibitory effects of flavonoids against Candida albicans by focusing our attention on genetic characterization of the strains examined. Moreover, using the C. albicans MLST-database, we performed a phylogenetic analysis showing the genetic variation occurring in this species.Results:Today, we have enough information to estimate genetic diversity within microbial species and recent data revealed that most of fungal pathogens show complex population structures in which not a single isolate can be designated as representative of the entire taxon. This is especially true for the highly divergent fungal pathogen C. albicans, in which the assumption that one or few “standard strains” can represent the whole species is overly unrealistic and should be laid to rest.Conclusion:The goal of this article is to shed light on the extent of genetic variation in C. albicans and how this phenomenon can largely influence the activity of flavonoids against this species.
The State of the Hemomycocirculatory Bed of Adventitia of Varicose Veins of the Small Pelvis in Women with Chronic Inflammatory Diseases of the Internal Genital Organs
Authors: Drohomyretska Natalya 
Published: December 2017

Hemomicrocirculatory system – is a complex structure that reacts in every pathological process even before the clinical period and takes the first blow. The study of microhemocirculation will provide an opportunity to solve the important for practical medicine questions of pathogenesis of many diseases, as for the prevention and treatment of regional disorders of blood circulation.The objective of the research is to study the state of the hemomicrocirculatory bed (HMCB) of adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the organs of the small pelvis (CIPOSP).Materials and methods of research. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, there were pieces of the ovarian vein. The study of the HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the condition of the HMCB of adventitia of the venous wall in norm was studied in 5 women of reproductive age, who died as a result of various traumas.Results of the research. After the performed studies, the structural-morphological changes of the HMCB of the adventitia of the small pelvis veins were revealed. The dilation of capillaries, postcapillaries, postcapillary venules was observed. The diameter of the vessels of the HMCB of the ovarian vein adventitia was: venule – 94.21 ± 1.38 μM in comparison with the norm – 48.78 ± 1.60 μM (p<0.001); post-capillary venules – 46.76 ± 1.04 μM in comparison with the norm – 28.29 ± 1.1.01 μM (p<0.001); the capillaries were 11.22 ± 0.14 μM in comparison with the norm – 8.24 ± 0.16 μM (p<0.05), arterioles – 29.02 ± 0.76 μM in comparison with the norm – 25.19 ± 1.15 μM (p<0.01). The architectonics of the arterioles is almost unchanged. Lumen of venules is filled with formed elements. The structure of capillaries is polymorphic. The capillary net was localized and concentrated or was formed as a thick planar net, the capillaries were expanded. There were arterio-venulous anastomoses. Endothelial nuclei are shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules. Conclusions:1. The first discovered by us changes in HMCB of adventitia of varicose veins of the small pelvis in women with CIPOSP can be one of the pathogenetic links of the development and progression of the varicose vein itself, which in turn aggravates the course of chronic inflammation. 2. The timely appointment of drugs that improve microcirculation will enable to prevent the development of dystrophic changes in the vein wall, improve the course of chronic inflammatory processes and reduce or completely eliminate the syndrome of “chronic pelvic pain”.
Артеріальна гіпертензія та фібриляція/тріпотіння передсердь: асоціативність зв’язку за даними епідеміологічного дослідження
Authors: Sribna O.V. , Sychov O.S. , Kvasha O.O. , Smyrnova I.P. 
Published: December 2017

Мета роботи: провести аналіз асоціативного зв’язку артеріальної гіпертензії з фібриляцією/тріпотінням передсердь на популяційному рівні. Матеріали та методи. Згідно з даними епідеміологічного обстеження 1975 осіб — мешканців м. Києва, проведеного за уніфікованою методикою, визначено силу та напрямок асоціативного зв’язку між підвищеним артеріальним тиском та порушеннями ритму серця у вигляді фібриляції/тріпотіння передсердь згідно з показниками відносного ризику, відношення шансів (ВШ) та популяційно-атрибутивного ризику. Результати. Встановлено, що наявність артеріальної гіпертензії достовірно підвищує вірогідність фібриляції/тріпотіння передсердь у жіночій популяції втричі (ВШ = 3,162, р = 0,09), серед чоловіків з артеріальною гіпертензією — майже вдвічі (ВШ = 1,889, р = 0,121). Позитивний ефект усунення такого фактора, як підвищений артеріальний тиск, щодо розвитку фібриляції/тріпотіння передсердь серед жінок становить 50,6 % згідно з розрахованим показником популяційно-атрибутивного ризику. Висновки. За даними епідеміологічного обстеження встановлено, що артеріальна гіпертензія — один із значущих факторів ризику щодо розвитку фібриляції/тріпотіння передсердь, корекція якого має вагоме значення в первинній профілактиці даних порушень серцевого ритму та запобіганні ускладнень у пацієнтів із фібриляцією/тріпотінням передсердь.
IS THE LOGIC OF LAW IN CONTRAST TO CHRISTIAN VALUES?
Authors: Trajković Marko 
Published: December 2017

Is it possible for logic of law to squeeze out Christian values, given that the nihilism towards values leads towards the rejection of the major role of the law, which is the protection and realization of values? Is the actual goal of the legal norm, as part of law and logical legal system turned into a command, to establish the behavior which carries out the Christian values it contains? Is the constitution, the law or some other act as the embodiment of the legal norm, really based on certain social and legal values? As opposed to the law, there is a man able to ponder and wonder. Does he live in accordance with the legal norms only out of fear of punishment? Would it be possible for the government to establish the legal system which would be totally based on the fear of sanctions? Can that kind of legal system ever become a stable whole, or might it be destroyed by itself? Is the reason for the failure of the system of the state and law insufficiently centralized government, for example, or the lack of Christian values in their very grounds? The answer to the question posed by St. Thomas Aquinas depends on the answers to the previously posed questions. The question posed by St. Thomas Aquinas is: is the law made only for the evil and the wicked? However, it would be naive to rely on the tendency of correlation between human behavior and his moral principles. The entire human history confirms the result. We are well equipped to find reasons for what we do, but we are not so good when we are to do something for which we see good reasons, for which the reasons are obvious. We often say to our children: “Do as I tell you”, forgetting that they watch and copy exactly what we do. One of the ways to strengthen the bonds between values-attitudes-behavior is to apply signs for encouragement which are supposed to empower the real behavior.
Karczmarczyk, P. (2012), El lenguaje privado a contrapelo, Buenos Aires- La Plata, EDULP, 370 páginas
Authors: Parra Fabiana 
Published: December 2017

Reseña: Karczmarczyk, P. (2012), El lenguaje privado a contrapelo, Buenos Aires- La Plata, EDULP, 370 páginas
Da mina de Socavão à mina a céu aberto: os novos pactos no caso do centro de mineração de Hualgayoc, Cajamarca, Peru
Authors: Penafiel Adriana Paola Paredes 
Published: December 2017

Este trabalho trata das dinâmicas da mineração a céu aberto e seus efeitos da região andina de Cajamarca, ao norte do Peru. Por meio de pesquisa de abordagem etnográfica, realizada entre 2013 e 2014, analisa-se como o desenho de uma mina a céu aberto na cidade de Hualgayoc influencia as pessoas que inicialmente desenhavam na terra, os velhos mineradores de socavão. O objetivo deste artigo é estudar como a mina moderna hierarquiza, classifica e burocratiza as relações com as pessoas do lugar. No entanto, esta impessoalidade por parte da mina não é aceita pela população local que procura estabelecer acordos, principalmente com o Gerente de Relações Comunitárias. Os sucessos dos pactos tem um efeito destruidor para os marginalizados desse processo que são os que sofrem o desemprego, os preços altos, a contaminação e falta de agua. A reflexão sobre esta forma de fazer pactos remete aos estudos da Antropologia sobre mineração e desenvolvimento.
Design of Lighting Control with RTC Timer and SMS Using Microcontroller
Authors: Agung IGAP Raka , Djuni H IGAK Diafari 
Published: December 2017

The purpose of this research is to make the switch to turn on and off lighting with time can be set based on certain conditions. Controller utilizes Arduino UNO microcontroller with input from DS1307 RTC IC, photodiode, IComSat V1.1 with the output of LCD display and lighting switch. In this study realized photodiode sensor to detect dark and light illumination, DS1307 RTC IC as a source of real-time equal to the time actually, IComSat v1.1 SIM900 GSM/GPRS Shield for Arduino to communicate with HP via SMS, switch circuit and drivers for turn on and off the load of lighting and Arduino UNO with programs that has been put into flash memory. Research results obtained are supporting components of the equipment control to turn on and off of lighting utilizing microcontroller can be realized and are functioning in accordance with the plan. Two lightings can already turn on and off based on the input time of the RTC (the default) and on off status can be checked by SMS. Both lightings can already be turn on and off by SMS messages sent from mobile HP and received by microconroller (IComSat) and feedback lighting conditions is already accepted by mobile HP corresponds to on and off lights condition.
Evaluation of Clipping and Filtering-Based PAPR Reduction in OFDM System
Authors: Wirastuti N. M. A. E. D. , Pramaita N. , Suyadnya I M. A. , Khrisne D. C. 
Published: December 2017

This paper investigates clipping and filtering techniques in reducing peak average power ratio (PAPR) of Orthogonal Frequency Division Multiplexing (OFDM) system. The concept of OFDM is to split a high speed serial data into parallel data at a lower speed, then the parallel data carried by mutually orthogonal subcarriers. The high of PAPR is one of disadvantages of OFDM system. The high PAPR can damages the form of OFDM and reduces its performance. The purpose of this study is to reduce PAPR using simulation. OFDM was simulated with and without clipping filtering then compared. The methods used to reduce PAPR was clipping and filtering technique. Clipping and filtering technique operates by clipping the output of inverse Fourier transform that exceed the threshold. Graphics PAPR vs. CCDF was used to evaluate the performance of OFDM systems. PAPR for OFDM system using Fourier transform when CCDF = 10-3 is 11,2 dB, with classical clipping PAPR was 4,1 dB and PAPR 4,6 dB when with deep clipping.
Study of The Electric Field Between Horizontal and Vertical Configuration Pole under 150 KV High Voltage Transmission Line (SUTT 150 KV)
Authors: Amrita Anak Agung Ngurah 
Published: December 2017

Distribution of electrical energy from a plant to a substation or from a substation to other substations usually uses a transmission line. In Bali, type of transmission line that is usually implemented is SUTT 150 kV. The magnitude of the applied voltage is an attempt to reduce power loss for long distance distribution. However, distributing electrical energy with increasing stress affects the increase of electric field around the transmission line. The negative impact of electricity distribution has been an environmental problem for PT. PLN (Persero), especially where there is conversion from an open area to be a residential. This problem has been the main reason for conducting this research. IRPA / INIRC recommendation states that exposure time is not limited to the electric field effect in work environment and public area including a residential area at frequency of 50/60 Hz is 5 kV/m. This recommendation is in accordance with SNI 04-6950-2003, on Threshold Limit Values ??Electric Field under SUTT and high-voltage wires. The first problem of this research is how large the intensity of the electric field between two poles of SUTT 150 kV with vertical and horizontal constructions which are built side by side? The second problem is what the characteristic of the electric field intensity between the two poles which are built side by side? From the analysis, it can be seen that the intensity of the electric field that occurs between the conductor of the vertical and horizontal pole configurations are still below the IRPA/INIRC and SNI 04-6950-2003 recommendation i.e. 1 up to 1.5 kV/m and at a distance of 18 meters to 25 meters there is an interaction of electric field intensity that occurs at these two configurations.