bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis and Characterization of Biologically Active Organosilicon and Organotin Complexes of Phenylglycyl Hydrazones.
Authors: AMINABHAVI T. M. , BIRADAR N. S. , PATIL S. B. , HOFFMAN D. E. , BIRADAR V. N. 
Published: May 2016

AbstractThe complexes (I) are prepared by mixing equimolar quantities of ligand with either Me2SiCl2 or Ph2SnCl2 in dry benzene (no yields given) and characterized by elemental analysis, conductivity measurements, IR and 1H NMR spectral data.
ChemInform Abstract: 2,3‐Dimethyl‐1‐ethyl‐1,2,3‐aluminadicarbadodecaborane: A Versatile Carbollyl Transfer Reagent.
Authors: JUTZI P. , GALOW P. 
Published: May 2016

AbstractThe o‐dicarborane (I) is converted to the title compound (IV) by reaction with triethyl aluminum (II) and subsequent heating.
ChemInform Abstract: Synthesis, Structure, and Spectroscopic Properties of Early Transition Metal η2‐Iminoacyl Complexes Containing Aryl Oxide Ligation.
Authors: CHAMBERLAIN L. R. , DURFEE L. D. , FANWICK P. E. , KOBRIGER L. , LATESKY S. L. , MCMULLEN A. K. , ROTHWELL I. P. , FOLTING K. , HUFFMAN J. C. , STREIB W. E. , WANG R. 
Published: May 2016

Abstractη2‐Iminoacyl complexes of Ti, Zr, Hf, and Ta have been synthesized by the migratory insertion of organic isocyanides into the metal‐alkyl bonds of a series of mixed alkyl‐aryloxy compounds.
ChemInform Abstract: EPR Study of the Cr(V) and Radical Species Produced in the Reduction of Cr(VI) by Ascorbate.
Authors: GOODGAME D. M. L. , JOY A. M. 
Published: May 2016

AbstractThe interaction between K2Cr2O7 and the ascorbate ion in aqueous solution at pH 7‐8.5 in unbuffered and buffered solution produces relatively long‐lived Cr(V) species.
ChemInform Abstract: Polynuclear Metal Complexes with Bridging Carbene or Carbyne Ligands. Part 49. Synthesis of Mixed‐Metal Complexes with Bonds Between Cr, Mo or W and Co, Rh, Ir or Re; Crystal Structure of (CrReRh2(μ3‐CC6H4Me‐4)(μ‐CO)(CO)9(η‐C9H7)2).
Authors: ABAD J. A. , DELGADO E. , GARCIA M. E. , GROSSE‐OPHOFF M. J. , HART I. J. , JEFFERY J. C. , SIMMONS M. S. , STONE F. G. A. 
Published: May 2016

AbstractReactions of the heterobinuclear carbyne complexes (I) with fragments of low‐valent Rh or Co complexes to produce multinuclear clusters are investigated.
ChemInform Abstract: Polynuclear Metal Complexes with Bridging Carbene or Carbyne Ligands. Part 50. Synthesis and Crystal Structures of the Complexes (RuW3(μ‐CO)(μ3‐η‐CO)(μ‐CPh)2(μ3‐CPh)(CO)2(η‐C5H5)3) and (RuW3(μ‐CO)(μ3‐η‐CO)(μ‐C(Ph)C(O))(μ‐CPh)(μ3‐CPh)(CO)(PMePh2)# (η‐C5H5)3).
Authors: FARRUGIA L. J. , JEFFERY J. C. , MARSDEN C. , SHERWOOD P. , STONE F. G. A. 
Published: May 2016

AbstractThe 3:1 molar reaction of the alkylidyne‐W complexes (I) with the Ru(0) complexes (II) leads to a chromatographically separable mixture of the cluster compounds (III) and (IV).
ChemInform Abstract: Oxidation of Hydrazine and Methyl‐Substituted Hydrazines by the Cyano Complexes of Iron(III), Molybdenum(V), and Tungsten(V). A Kinetic Study.
Authors: DENNIS C. R. , VAN WYK A. J. , BASSON S. S. , LEIPOLDT J. G. 
Published: May 2016

AbstractElectron‐transfer between N2H4, MeNH‐NH2, MeNH‐NHMe and (Fe(CN)6)3‐ and (M(CN)8)3‐ (M: Mo, W) in aqueous solution proceeds via an outer‐sphere mechanism.
ChemInform Abstract: Syntheses of Photoactive Complexes. Electronic Spectra, Electrochemistry, and SCF‐Xα‐DV Calculations for Bis(phosphine)palladium Oxalate and Dithiooxalate Complexes. Crystal and Molecular Structures of (Dithiooxalato‐S,S′)bis(trimethylphosphine)palladium(II) and (1,1‐Dithiooxalato‐S,S′)bis(μ3‐sulfido)‐2,2,3,3‐tetrakis(trimethylphosphine)# ‐triangulo‐tripalladium(II).
Authors: COWAN R. L. , POURREAU D. B. , RHEINGOLD A. L. , GEIB S. J. , TROGLER W. C. 
Published: May 2016

AbstractThe dithiooxalate complexes (II) are prepared as shown.
ChemInform Abstract: Synthesis of Metal Complexes of Antimalarial Drugs and in vitro Evaluation of Their Activity Against Plasmodium falciparum.
Authors: WASI N. , SINGH H. B. , GAJANANA A. , RAICHOWDHARY A. N. 
Published: May 2016

AbstractThe two well known antimalarials amodiaquine and primaquine react with corresponding metal salts in stoichiometric ratio to afford the 1:1 amodiaquine metal complexes (I) and the 2:1 or 3:1 primaquine complexes (II).
ChemInform Abstract: Formation of a Hexoseptanose by Unusual Rearrangements of a Furanoid Glycal.
Authors: CSUK R. , GLAENZER B. I. + , FUERSTNER A. + , WEIDMANN H. , FORMACEK V. 
Published: May 2016

AbstractTreatment of the tosylate (I) with potassium tert‐butoxide generates the glycal (II) which rearranges on prolonged reaction to give the anti‐Bredt product (III).
ChemInform Abstract: Optical and Spectromagnetical Properties of Phosphate Glasses Containing Ruthenium and Titanium Ions.
Authors: PIZZINI S. , NARDUCCI D. , DAVERIO D. , MARI C. M. , MORAZZONI F. , GERVASINI A. 
Published: May 2016

AbstractIn order to study the influence of transition metal oxides on the electronic properties of TiO2‐ and RuO2‐based phosphate glasses, the optical and structural properties of Ru(III) and Ti(III) in these glasses are investigated by ESR and UV and visible absorption techniques.
High quality, good health: The case for olive oil
Authors: Bernardini Elena , Visioli Francesco 
Published: May 2016

The healthful properties of olives and their main derivatives are being actively investigated. In this review, we briefly appraise and descriptively review the most recent evidence on the purported correlations between olive oil consumption and health, and we provide some bibliometric analyses that show how fast the field of “olive components and health” is indeed moving. Based on accumulated findings, we expect olive oil (and related products) research to further grow in the next few years, when more olive‐derived nutraceuticals and functional foods will enter the market and when targeted basic mechanism research will further clarify the manifold mechanisms of action of olive (poly)phenols.Practical applications:Our findings underscore the need to produce and consume high quality olive oil, whose “minor components” are endowed with heathful properties.The use of high‐quality extra‐virgin olive oil activates a virtuous cycle by which consumers become more aware of their health and of the influence of proper diet on it. This translates into a better overall diet and, in turn, better prognosis.
Influence of deodorization temperature on formation of tocopherol esters and fatty acids polymers in vegetable oil
Authors: Kreps František , Kyselka Jan , Burčová Zuzana , Schmidt Štefan , Rajchl Aleš , Filip Vladimír , Ház Aleš , Jablonský Michal , Sládková Alexandra , Šurina Igor 
Published: May 2016

The paper describes laboratory deodorization of rapeseed oil (Ro), model sunflower (SoM), and model rapeseed (RoM) oils, its effect on the tocopherol content and the kinetics of tocopherol degradation. We now present a novel approach to analysis of alpha‐tocopherol degradation product as well as kinetic study esters of alpha‐tocopherol with fatty acids and alpha‐tocopheryl quinones. Alpha‐tocopherol esters were found to be the principal products of tocopherols degradation in high temperature experiment. A laboratory deodorization, lasting 2 h caused formation of 70–128 mg/kg of alpha‐tocopherol esters in model oils and 25 mg/kg of alpha‐tocopherol esters in rapeseed oil without modification. The commercially available sunflower and rapeseed oils contained 3–12 mg/kg of alpha‐tocopherol esters. The alpha‐tocopherol esters are formed at higher rate than alpha‐tocopheryl quinone, which was unstable at high deodorization temperature. Tocopherols took no part in non‐radical thermal reactions, taking place in second high‐temperature experiments with oxygen‐free atmosphere. We proved by DART TOF‐MS the formation of polymeric fatty acids via Diels–Alder reaction taking place in heated oils.Practical applications: Although an extensive research have been conducted in the area of high‐temperature degradation of tocopherols, this is the first report on formation of fatty acids esters of tocopherols during oil deodorization. The proof of their presence in deodorized oils, deodorization condensates, deep‐fried foods, and oils constitutes a breakthrough. We ingested them as yet unknowingly. Their degradation is not nearly as fast as that of tocopherol itself or its oxidation products. In the course of their hydrolysis in stomach tocopheryls of fatty acids could thus become the source of unoxidized tocopoherols.We found out that during laboratory deodorization of vegetable oils were formed esters of tocopherols with fatty acids. During heating of oils are free fatty acids the acid catalyst of esterification.
CLOCK promotes 3T3‐L1 cell proliferation via Wnt signaling
Authors: Zhu Zhu , Hua Bingxuan , Xu Lirong , Yuan Gongsheng , Li Ermin , Li Xiaobo , Sun Ning , Yan Zuoqin , Lu Chao , Qian Ruizhe 
Published: May 2016

AbstractCircadian genes control most of the physiological functions including cell cycle. Cell proliferation is a critical factor in the differentiation of progenitor cells. However, the role of Clock gene in the regulation of cell cycle via wingless‐type (Wnt) pathway and the relationship between Clock and adipogenesis are unclear. We found that the circadian locomotor output cycles kaput (Clock) regulated the proliferation and the adipogenesis of 3T3‐L1 preadipocytes. We found that Clock attenuation inhibited the viability of 3T3‐L1 preadipocytes in the cell counting kit 8. The expression of c‐Myc and Cyclin D1 decreased dramatically in 3T3‐L1 when Clock was silenced with short interfering RNA and was also decreased in fat tissue and adipose tissue‐derived stem cells of ClockΔ19 mice. Clock directly controls the expression of the components of Wnt signal transduction pathway, which was verified by serum shock, chromatin immunoprecipitation, Western blot, and quantitative real‐time polymerase chain reaction (qRT‐PCR). Furthermore, IWR‐1, a Wnt signal pathway inhibitor, inhibited the cell cycle promotion by CLOCK, which was detected by cell viability assay, flow cytometry, and qRT‐PCR. Therefore, CLOCK transcription control of Wnt signaling promotes cell cycle progression in 3T3‐L1 preadipocytes. Clock inhibited the adipogenesis on day 2 in 3T3‐L1 cells via Oil Red O staining and qRT‐PCR detection and probably related to cellular differentiation. These data provide evidence that the circadian gene Clock regulates the proliferation of preadipocytes and affects adipogenesis. © 2016 IUBMB Life, 68(7):557–568, 2016
Selective binding of estrogen receptor α to ubiquitin chains
Authors: Pesiri Valeria , Di Muzio Elena , Polticelli Fabio , Acconcia Filippo 
Published: May 2016

AbstractUbiquitin (Ub)‐binding domains (UBDs) noncovalently contact the Ub modification on binding partners. Ub possesses seven lysine (K) residues (i.e., K6, K11, K27, K29, K33, K48, and K63) that can be used to form different chains based on different Ub linkage types (e.g., monoubiquitination/polyubiquitination). Thus, different Ub‐based signals exist and are decoded by UBDs. Recently, we have reported the existence of two Ub binding surfaces located within the estrogen receptor α (ERα) protein. We have shown that the leucine (L) 429 and alanine (A) 430 ERα residues direct noncovalent receptor binding to K63‐based Ub chains in vitro. However, mutation of L429 and A430 residues did not completely abolish the ability of ERα to associate with Ub in cell lines. Thus, we evaluated the possibility that one or both ERα Ub binding surfaces could non‐covalently interact with other Ub chains. Here, we report that ERα selectively binds to specific Ub chains based on different Ub linkages and that ERα monoubiquitination requires non‐covalent ERα:Ub binding. Considering the importance of the UBD:Ub interaction in the initiation and progression of many diseases (e.g., cancer), our data provide novel insights into ERα functions that could be relevant to ERα‐related diseases. © 2016 IUBMB Life, 68(7):569–577, 2016
ESI‐MS/MS of expanded porphyrins: a look into their structure and aromaticity
Authors: Ramos Catarina IV , Figueira Flávio , Polêto Marcelo D , Amado Francisco ML , Verli Hugo , Tomé João PC , Neves M Graça PMS 
Published: May 2016

Electrospray mass spectrometry/mass spectrometry was used to investigate the gas‐phase properties of protonated expanded porphyrins, in order to correlate those with their structure and conformation. We have selected five expanded meso‐pentafluorophenyl porphyrins, respectively, a pair of oxidized/reduced fused pentaphyrins (22 and 24 π electrons), a pair of oxidized/reduced regular hexaphyrins (26 and 28 π electrons) and a regular doubly N‐fused hexaphyrin (28 π electrons).The gas‐phase behavior of the protonated species of oxidized and reduced expanded porphyrins is different. The oxidized species (aromatic Hückel systems) fragment more extensively, mainly by the loss of two HF molecules. The reduced species (Möbius aromatic or Möbius‐like aromatic systems) fragment less than their oxidized counterparts because of their increased flexibility. The protonated regular doubly fused hexaphyrin (non‐aromatic Hückel system) shows the least fragmentation even at higher collision energies.In general, cyclization through losses of HF molecules decreases from the aromatic Hückel systems to Möbius aromatic or Möbius‐like aromatic systems to non‐aromatic Hückel systems and is related to an increase in conformational distortion. Copyright © 2016 John Wiley & Sons, Ltd.
Human resource management systems and work attitudes: The mediating role of future time perspective
Authors: Korff Jörg , Biemann Torsten , Voelpel Sven C. 
Published: May 2016

SummaryThis paper examines the role of employees' future time perspective (FTP) in the association between human resource management (HRM) systems and work‐related attitudes. Drawing on social exchange theory, signaling theory, and affective events theory, we hypothesize HRM systems' indirect effects on individual‐level job satisfaction and affective organizational commitment as mediated by FTP. The results of this multilevel study, comprising 913 employees of 76 business units, provide evidence that HRM systems have (i) direct effects on employees' FTP and (ii) indirect effects on job satisfaction and organizational commitment via FTP. In addition, three HRM bundles' (i.e., knowledge, skills, and abilities enhancing; motivation enhancing; and opportunity enhancing) corresponding indirect effects are explored. We discuss the results, theoretical contributions, and practical implications of the study, as well as future research directions. Copyright © 2016 John Wiley & Sons, Ltd.
The dynamic state of the ionome in roots, nodules, and shoots of soybean under different nitrogen status and at different growth stages
Authors: Chu Qingnan , Watanabe Toshihiro , Shinano Takuro , Nakamura Takuji , Oka Norikuni , Osaki Mitsuru , Sha Zhimin 
Published: May 2016

AbstractThe relative distribution of 22 mineral elements in the roots, nodules and shoots of the soybean (Glycine maxL. Merr. cv. Tsurumusume) at R1 (beginning of the flowering stage) and R7 (beginning of the mature stage) was investigated in response to ammonium and manure N treatment. Plants receiving only atmospheric nitrogen served as the negative control. The addition of ammonium sulfate to the soil caused soil acidification, induced Al and Mn toxicities, and significantly reduced the biomass production in roots and nodules. Ca, Mg, Fe, Mn, Cu, and Zn concentrations were significantly higher in shoots, and those of Mo and Co higher in nodules. The addition of manure to the soil significantly enhanced the levels of Sr, Ba, Cr, and Cd in shoots, whereas the concentration of Cs was decreased at R7. Moreover, when the soybean developed from R1 to R7, the levels of essential elements in nodules decreased, whereas those of nonessential elements increased, irrespective of the nitrogen source. Furthermore, the variation in the concentrations of many elements was not consistent for nodules and roots when soybean developed from R1 to R7. The variation of Mn, Zn, B, and Al concentrations was independent of N treatments. However, Ca, Fe, Cu, Mo, and Se levels were affected strongly by N treatments. This study is the first to document the dynamic variation of the soybean ionome in nodules, roots, and shoots from vegetative to reproductive stage of soybean.
‘To Adopt or not to Adopt?’ Legume Adoption in Maize‐Based Systems of Northern Thailand: Constraints and Potentials
Authors: Yap Von Yi , de Neergaard Andreas , Bruun Thilde Bech 
Published: May 2016

AbstractA considerable growth in the maize (Zea mays L.) sector in Southeast Asia has resulted in a rapid expansion and intensification of maize monoculture on sloping uplands. This practice entailed the heavy use of fertilisers, leading to environmental degradation and farmers' indebtedness. Intercropping of legumes with maize could complement or replace fertiliser inputs; however legume adoption by smallholder maize farmers remains low. This study investigates the constraints and potentials to integrate legumes in maize‐based cropping systems in such environments. A comparative study between maize monocropping and maize/legume relay cropping was carried out in two villages of Thailand, using surveys, participatory rural appraisal (PRA) tools and interviews. The results demonstrated that both cropping systems were equally profitable, although the maize yield in maize/legume relay cropping was lower than that in monocropping. Low selling price was the most cited reason by the non‐adopters for not introducing legumes. Selling price of legume grains, ease of harvesting, marketability and ease of growing were the four main criteria that determined the adopters' choice of legume species. Among the cultivated legumes, ricebean (Vigna umbellata L.) best fulfilled the criteria for the choice of legume species. Establishing maize/legume relay cropping as an alternative to maize monocropping under rainfed conditions can decrease risks, due to reduced expenses for farm inputs and similar economic returns. This study generated useful information for agricultural policy makers and development practitioners in identifying the barriers and facilitating factors that influence farmers' decision to adopt legumes and the conditions that shape the farmers' decision‐making environment. Copyright © 2016 John Wiley & Sons, Ltd.
The Determination of Calcium in Natural Waters1
Authors: CARPENTER JAMES H. 
Published: May 2016

A procedure for the determination of calcium in natural waters is presented which is faster, more precise, and more accurate than those previously described. Photometric weight titration with ethylenediamine‐tetraacetate ion in the presence of ammonium purpurate is employed following isolation of the calcium by ion‐exchange chromatography. Calcium is separated from magnesium and strontium by the use of acetylacetone as a complexing elutant.Samples of sea water from the Bahamas region were examined by this procedure, and good agreement was found with reported values determined by the classical triple oxalate procedure. The calcium content is one per cent higher than that which would be expected from the accepted calcium‐chlorinity ratio. In addition, samples from the Chesapeake Bay indicate that the sea water source for this region has a greater calcium content than would be expected from the accepted calcium‐chlorinity ratio for sea water.
High Botulinum Toxin‐Neutralizing Antibody Prevalence Under Long‐Term Cervical Dystonia Treatment
Authors: Hefter Harald , Rosenthal Dietmar , Moll Marek 
Published: May 2016

AbstractBackgroundThe aim of this study was to determine the prevalence of neutralizing antibodies in a large cohort of long‐term treated patients with cervical dystonia (CD) still responding to repetitive injections with botulinum toxin (BoNT).MethodsConsecutively recruited CD patients (n = 221) under long‐term BoNT treatment (≥2–21 years) underwent a clinical examination at the same time blood samples were taken for neutralizing antibody determination. Collected data included demographics, mean dose of the last 10 botulinum injections, treatment duration, Tsui score for CD severity, and patients' subjective impression of treatment effect. Blood samples were screened for antibody presence by ELISA; positive samples were further analyzed by mouse hemidiaphragm test. The two laboratories performing antibody testing were blinded to the coded samples.ResultsAntibody status could be determined for 212 patients; 39 (18.4%) were ELISA positive and 31 (14.6%) additionally positive in the mouse hemidiaphragm test. Patients with positive neutralizing antibody titers had significantly higher Tsui scores and were treated for a significantly longer time with significantly higher doses. There were no differences between male and female patients and between onabotulinumtoxinA‐ and abobotulinumtoxinA‐treated patients. When BoNT preparations had been switched during the last 10 injections, a significantly higher proportion of neutralizing antibody‐positive patients was detected.ConclusionsNeutralizing antibody prevalence in long‐term treated, still responding CD patients is substantially higher than suggested by follow‐up studies with a shorter time frame. It should therefore be emphasized that antigenicity of BoTN preparations is still a relevant problem and should be taken into account in long‐term treatment decisions.
Identification of impaired fasting glucose, healthcare utilization and progression to diabetes in the UK using the Clinical Practice Research Datalink (CPRD)
Authors: Hong Jin‐Liern , McNeill Ann Marie , He Jinghua , Chen Yong , Brodovicz Kimberly G. 
Published: May 2016

AbstractPurposeFew studies have examined patients with prediabetes in usual, “real‐world” clinical practice settings. Among patients with impaired fasting glucose (IFG), we aimed to describe the rates of progression to diabetes and to examine the long‐term reduction in diabetes risk associated with regression to normoglycemia at 1 year.MethodsThe UK‐based study included 120 055 non‐diabetic patients in Clinical Practice Research Datalink from 2001 to 2012 aged 25+ years and with ≥1 fasting plasma glucose (FPG) test between ≥6.1 and <7.0 mmol/l indicating IFG who were followed for progression to diabetes. In a subgroup of 45 167 patients with IFG with subsequent FPG results 1 year later, we assessed the 1‐year glycemic status change and estimated the relative hazard of diabetes comparing patients with regression to normoglycemia (IFG–normoglycemia) to those who remained in IFG (IFG–IFG) using a multivariable Cox model.ResultsAmong patients with IFG with over 414 649 person‐years of follow‐up, 52% received a subsequent FPG test, and 10% developed diabetes within 1 year after recognition of IFG. The incidence rate of diabetes was 5.86 (95% CI: 5.78 to 5.93) per 100 person‐years. In the subgroup analysis, 31% of these patients remained in IFG, while 53% and 16% converted to normoglycemia or diabetes, respectively. The adjusted hazard ratio of developing diabetes was 0.33 (95% CI: 0.31 to 0.35) comparing IFG–normoglycemia to IFG–IFG.ConclusionsIFG is a high‐risk state for diabetes. Regression to normoglycemia from IFG strongly reduces the long‐term risk of developing diabetes. Our study also shows the feasibility of identifying patients with IFG in the Clinical Practice Research Datalink. Copyright © 2016 John Wiley & Sons, Ltd.