bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hospital performance dashboards: a literature review
Authors: Buttigieg Sandra C. , Pace Adriana , Rathert Cheryl 
Published: May 2017

Purpose
The purpose of this paper is to give a comprehensive and updated analysis of the available literature on hospital dashboards.

Design/methodology/approach
A search of the current literature was performed by searching electronic databases, including Google Scholar, EBSCO and Medline, as well as books.

Findings
In all, 48 manuscripts consisting of peer reviewed articles, conference proceedings, case reports and text books were included in this review.

Practical implications
Despite the numerous advantages of performance dashboards, several authors have mentioned a number of challenges. It was evident from the literature that any setting requires significant effort, especially to ensure the quality of data being collected. In fact, significant investment, both in terms of financial and human resources, is required to achieve an effective dashboard. Furthermore, most of the studies available in the literature were individual case reports or anecdotal accounts rather than empirical studies. Thus, further research is required to ascertain the effectiveness of performance dashboards. In view of these findings, each organisation should make its own decisions whether or not to adopt performance dashboards.

Originality/value
Most of the literature is fragmented as it reports the use of different types of dashboards, namely strategic, tactical and operational, as separate tools. This literature review contributes to knowledge as it brings together the different types of dashboards and the cascading effect of one dashboard onto another in order to achieve and retain organisational alignment with the overall strategic goals.
An analysis of the changing role of systems librarians
Authors: Ratledge David , Sproles Claudene 
Published: May 2017

Purpose
The purpose of this paper is to analyze technology-related librarian advertisements to examine the changing role of the systems librarian in today’s modern, technology-filled libraries.

Design/methodology/approach
The authors examined 70 advertisements for technology-focused librarians posted on ALA’s JobList in 2014. The ads were examined for area of focus and required knowledge and experiences.

Findings
The ads revealed three main areas of focus: traditional systems, digital initiatives, and web services. In addition to traditional computer and library systems skills, employers were seeking candidates with project management, digital collection, customer service, technology implementation, and problem solving skills and experience.

Practical implications
This study highlights how the adoption and expansion of library technology has altered the roles and responsibilities of systems librarians. Instead of solely focusing on maintaining library databases and ILSs, technology librarians have branched out and become more integrated within the library.

Originality/value
This study has implications for those entering the library field and LIS programs, as well as gaining insight into the expanding role of technology librarians today’s library.
Personal digital archiving: influencing factors and challenges to practices
Authors: Sinn Donghee , Kim Sujin , Syn Sue Yeon 
Published: May 2017

PurposeThe purpose of this paper is to investigate the associations of personal archiving behaviors to factors and challenges that have been assumed to affect personal digital archiving strategies.Design/methodology/approachThis study created an online survey to understand general patterns of personal digital archiving practices and related phenomena. The survey was employed to investigate to what extent people show a certain behavior or feel certain factors and challenge when archiving personal digital content.FindingsSome of the findings of this study regarding specific personal digital archiving practices were in accordance with existing studies. However, the associations between digital archiving challenges and archiving practices were not observed statistically significantly as assumed in previous studies. General technology efficacy and the awareness of the importance of personal records appeared to influence personal archiving practices.Research limitations/implicationsThis study used Amazon’s Mechanical Turk. As this is not a commonly used internet service, the workers here could have higher than average levels of internet efficacy. This possibility may have affected the demographics, and the survey responses may be biased in this respect.Practical implicationsAs the study results suggest that technology efficacy and personal heritage awareness are the influencing factors of personal digital archiving, these are the areas where information professionals can involve in assisting users for future cultural heritage.Originality/valueThis is the first study that develops measures for personal digital archiving related practices and perceptions that the previous qualitative studies have identified. With these measures, it examines the general status of individuals’ archiving strategies and the overall associations of digital archiving challenges as well as looking into other technological and personal factors.
Research data management in Turkey: perceptions and practices
Authors: Aydinoglu Arsev Umur , Dogan Guleda , Taskin Zehra 
Published: May 2017

Purpose
The massive increase in research data being produced nowadays has highlighted the importance of research data management (RDM) to science. Research data not only have to be cost effective but also reliable, discoverable, accessible, and reusable. In this regard, the purpose of this paper is to investigate the perceptions and practices of Turkish researchers on the subject of RDM.

Design/methodology/approach
An online survey was distributed to the academicians in 25 universities in Turkey, and 532 responses were gathered.

Findings
Results indicate that although Turkish researchers are aware of the benefits of data management, are willing to share their research data with certain groups, and have decent preservation habits, they express that they lack the technical skills and knowledge needed for RDM. In addition, no institutionalized support (staff, training, software, and hardware) is provided to researchers.

Research limitations/implications
A well-structured data strategy or policy that includes resource allocation (awareness, training, software/hardware) and is supported by Turkish research agencies is required for better data management practices among researchers in Turkey.

Originality/value
This is the first study that investigates the data practices of Turkish academics who produce around 30,000 scientific articles annually that are indexed by Web of Science. It contributes to the growing literature on RDM.
A Pseudo‐One Compartment Model of Phosphorus Kinetics During Hemodialysis: Further Supporting Evidence
Authors: Leypoldt John K. , Agar Baris U. , Cheung Alfred K. , Bernardo Angelito A. 
Published: May 2017

AbstractA pseudo‐one compartment model has been proposed to describe phosphorus kinetics during hemodialysis and the immediate post‐dialysis period. This model assumes that phosphorus mobilization from tissues is proportional to the difference between the pre‐dialysis serum concentration (a constant) and the instantaneous serum concentration. The current study is exploratory and evaluated the ability of a pseudo‐one compartment model to describe the kinetics of phosphorus during two short hemodialysis treatments separated by a 60‐min inter‐treatment period without dialysis; the latter is the post‐dialysis rebound period for the first short hemodialysis treatment. Serum was collected frequently during both hemodialysis treatments and the inter‐treatment period to assess phosphorus kinetics in 21 chronic hemodialysis patients. Phosphorus mobilization clearance and pre‐dialysis central distribution volume were previously estimated for each patient during the first hemodialysis treatment and the inter‐treatment period. Assuming those kinetic parameters remained constant for each patient, serum phosphorus concentrations during the second treatment were used to estimate the driving force concentration (Cdf) for phosphorus mobilization from tissues during the second treatment. Treatment time (117 ± 14 [mean ± standard deviation] vs. 117 ± 14 min), dialyzer phosphorus clearance (151 ± 25 vs. 140 ± 32 mL/min), and net fluid removal (1.44 ± 0.74 vs. 1.47 ± 0.76 L) were similar during both short hemodialysis treatments. Measured phosphorus concentration at the start of the second hemodialysis treatment (3.3 ± 0.9 mg/dL) was lower (P < 0.001) than at the start of the first treatment or Cpre (5.4 ± 1.9 mg/dL). Calculated Cdf was 4.9 ± 2.0 mg/dL, not significantly different from Cpre (P = 0.12). Cdf and Cpre were correlated (R = 0.72, P < 0.001). The results from this study demonstrate that the driving force concentration for phosphorus mobilization during hemodialysis is constant and not different from that pre‐dialysis, providing further evidence supporting a fundamental assumption of the pseudo‐one compartment model.
The Role of Friendship Reciprocity in University Freshmen's Alcohol Consumption
Authors: Giese Helge , Stok F. Marijn , Renner Britta 
Published: May 2017

BackgroundThe similarity of friends in the frequency and quantity of alcohol consumption is explored.MethodDuring their first semester, 57 psychology freshmen indicated weekly drinking frequency and quantity and nominated the three peers of this group they liked most. These nominations were then used to derive the weekly alcohol consumption of friends that either did or did not reciprocate a nomination.ResultsMultilevel modeling of weekly variations showed that individuals' drinking frequency was similar to peers who reciprocated a friendship (b = 0.15, p = .001), but not to non‐reciprocating peers (b = −0.01, p = .720). In contrast, weekly variation in quantity of individual students' drinking was similar to both reciprocating (b = 0.11, p = .018) and non‐reciprocating peers’ drinking (b = 0.10, p = .014). Yet across all weeks, quantity tended only to be similar to non‐reciprocating peers (b = 0.49, p = .020).ConclusionsFreshmen might spend drinking time with peers who reciprocate a friendship, but are similar regarding the quantity of drinks consumed to all people they find interesting. Thus, alcohol consumption is used strategically for social purposes. This social purpose should also be acknowledged in alcohol‐reduction interventions.
A rapid analytical method of major milk proteins by reversed‐phase high‐performance liquid chromatography
Authors: Ma Lu , Yang Yongxin , Chen Jingting , Wang Jiaqi , Bu Dengpan 
Published: May 2017

AbstractA reversed‐phase high‐performance liquid chromatography (RP‐HPLC) method with rapid and automated analysis, good separation, high resolution, high accuracy and reproducible results was successfully developed and used to separate and quantify the major cow milk proteins within 30 min analytical time. Standard solutions of single purified cow milk proteins were used to develop calibration equations. The RP‐HPLC method was validated with respect to intra‐day repeatability, inter‐day precision, linearity, accuracy and limit of detection (LOD). The recoveries of the RP‐HPLC analyses of major milk proteins from cows ranged 71.0–114%, the inter‐day precision was expressed as the relative standard deviation, and the ranged from 1.51 to 4.60% and the LOD ranged from 0.08 g/L to 0.28 g/L. Major proteins in cow were quantified according to the chromatographic profiles. Results showed that a rapid RP‐HPLC method for quantifying the major cow milk proteins was developed, which could be used to determine milk protein contents in the dairy industry.
Does body image influence the relationship between body weight and breastfeeding maintenance in new mothers?
Authors: Swanson Vivien , Keely Alice , Denison Fiona C. 
Published: May 2017

ObjectivesObese women have lower breastfeeding initiation and maintenance rates than healthy weight women. Research generally focuses on biomedical explanations for this. Psychosocial factors including body image and well‐being after childbirth are less well understood as predictors of breastfeeding. In obese and healthy weight women, we investigated changes in body image between 72 hrs post‐delivery and 6–8 weeks post‐natal, studying how women's body image related to breastfeeding initiation and maintenance. We also investigated how psychological distress was related to body image.DesignLongitudinal semi‐structured questionnaire survey.MethodsBody image and psychological distress were assessed within 72 hrs of birth and by postal questionnaire at 6–8 weeks, for 70 obese and 70 healthy weight women initiating exclusive (breastmilk only) breastfeeding or mixed feeding (with formula milk) in hospital. Breastfeeding was re‐assessed at 6–8 weeks.ResultsObese women were less likely to exclusively breastfeed in hospital and maintain breastfeeding to 6–8 weeks. Better body image was related to maintaining breastfeeding and to lower post‐natal psychological distress for all women, but education level was the most significant predictor of maintenance in multivariate regression including body image and weight status. Body image mediated, but did not moderate the relationship between weight and breastfeeding maintenance. Body image was lower overall in obese women, but all women had low body image satisfaction around childbirth, reducing further at 6–8 weeks.ConclusionsHealth professionals should consider women's body image when discussing breastfeeding. A focus on breast function over form may support breastfeeding for all women.
Statement of contribution

What is already known on this subject?

Obesity can negatively affect breastfeeding initiation and maintenance, but there is little information about how psychosocial factors affect this relationship. Body image may be an important factor, but has not been studied in relation to breastfeeding maintenance.

What does this study add

This article examines the influence of body image on obese and healthy‐weight women's breastfeeding maintenance at 6–8 weeks.

Different aspects of body image mediated but did not moderate the relationship between weight status and breastfeeding maintenance, but in multivariate regression, maternal education level was the most significant predictor.

Obese women had poorer body image and were less likely to maintain breastfeeding; however, for all women, body image became more negative in this postpartum period.

Interventions should normalize positive aspects of women's postnatal bodies, including function rather than form. Addressing body concerns could encourage new mothers to maintain breastfeeding, irrespective of weight status.
Institutional apologies and socio‐emotional climate in the South American context
Authors: Bobowik Magdalena , Páez Darío , Arnoso Maitane , Cárdenas Manuel , Rimé Bernard , Zubieta Elena , Muratori Marcela 
Published: May 2017

This study examined perceptions of institutional apologies related to past political violence and socio‐emotional climate among victims and non‐victims in Argentina (n = 518), Chile (n = 1,278), and Paraguay (n = 1,172) based on quasi‐representative samples. The perceptions of apology as sincere and efficient in improving intergroup relations were associated with a positive socio‐emotional climate across the three nations. Victims evaluated apologies more positively and perceived a more positive socio‐emotional climate compared to non‐victims in Paraguay and Argentina, whereas the opposite was true in Chile where the government opposed the victims’ leftist political orientation. The evaluations of apologies also mediated the effects of exposure to violence on the perception of socio‐emotional climate, but these effects were moderated by the context. Together, these findings suggest that apologies reinforce positive sociopolitical climate, and that, personal experience of victimization is an important factor determining these effects.
Is higher inequality less legitimate? Depends on How You Frame it!
Authors: Bruckmüller Susanne , Reese Gerhard , Martiny Sarah E. 
Published: May 2017

Economic inequality is increasing both globally and in various countries around the world, and such inequality has been linked to worsening health, well‐being, and social cohesion. A key predictor for whether people take action against inequality is the extent to which they perceive it as illegitimate. We investigate how two variables jointly predict the legitimization of inequality, namely the perceived magnitude of differences in economic outcomes and the way these differences are described. Two experiments (total N = 190) tested whether framing the same difference in outcomes as an advantaged group having more or as a disadvantaged group having less moderates whether higher inequality is perceived as less legitimate. Participants perceived bigger differences as less legitimate when these differences were framed as the disadvantaged group having less. When they were framed as the advantaged group having more, the perceived magnitude of differences and legitimacy beliefs were unrelated. Together, this research highlights the importance of language for how people perceive and respond to inequality.
Translation of WNT developmental programs into stem cell replacement strategies for the treatment of Parkinson's disease
Authors: Toledo Enrique M , Gyllborg Daniel , Arenas Ernest 
Published: May 2017

Wnt signalling is a highly conserved pathway across species that is critical for normal development and is deregulated in multiple disorders including cancer and neurodegenerative diseases. Wnt signalling is critically required for midbrain dopaminergic (mDA) neuron development and maintenance. Understanding the molecular processes controlled by Wnt signalling may thus hold the key to understand the physiopathology and to develop novel therapies aimed at preventing the loss of mDA neurons in Parkinson's disease (PD). Pharmacological tools to activate Wnt signalling have been used to translate in vivo developmental processes into protocols for the generation of bona fide mDA neurons from human pluripotent stem cells. Moreover, these protocols are currently being fine‐tuned to generate mDA neurons for clinical trials in PD. At the same time, a vast amount of molecular details of Wnt signalling continues to emerge and remains to be implemented into new protocols. We hereby review novel pharmacological tools to activate Wnt signalling and how single‐cell RNA‐sequencing is contributing to unravel the complexity of this pathway in the developing human ventral midbrain, generating novel hypotheses and identifying new players and opportunities to further improve cell replacement therapy for PD.Linked ArticlesThis article is part of a themed section on WNT Signalling: Mechanisms and Therapeutic Opportunities. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v174.24/issuetoc
Combination therapy with telmisartan and parecoxib induces regression of endometriotic lesions
Authors: Nenicu Anca , Gu Yuan , Körbel Christina , Menger Michael D , Laschke Matthias W 
Published: May 2017

Background and PurposeTelmisartan suppresses the development of endometriotic lesions. However, the drug also up‐regulates the expression of COX‐2, which has been suggested to promote the progression of endometriosis. Accordingly, in the present study we analysed whether a combination therapy with telmisartan and a COX‐2 inhibitor may be more effective in the treatment of endometriotic lesions than the application of telmisartan alone.Experimental ApproachEndometriotic lesions were induced in the peritoneal cavity of C57BL/6 mice, which were treated daily with an i.p. injection of telmisartan (10 mg·kg−1), parecoxib (5 mg·kg−1), a combination of telmisartan and parecoxib or vehicle. Therapeutic effects on lesion survival, growth, vascularization, innervation and protein expression were studied over 4 weeks by high‐resolution ultrasound imaging as well as immunohistochemical and Western blot analyses.Key ResultsTelmisartan‐treated lesions exhibited a significantly reduced lesion volume when compared with vehicle‐treated controls and parecoxib‐treated lesions. This inhibitory effect of telmisartan was even more pronounced when it was used in combination with parecoxib. The combination therapy resulted in a reduced microvessel density as well as lower numbers of proliferating Ki67‐positive cells and higher numbers of apoptotic cleaved caspase‐3‐positive stromal cells within the lesions. This was associated with a lower expression of COX‐2, MMP‐9 and p‐Akt/Akt when compared with controls. The application of the two drugs further inhibited the ingrowth of nerve fibres into the lesions.Conclusions and ImplicationsCombination therapy with telmisartan and a COX‐2 inhibitor represents a novel, effective pharmacological strategy for the treatment of endometriosis.
Vitamin D receptor agonists regulate ocular developmental angiogenesis and modulate expression of dre‐miR‐21 and VEGF
Authors: Merrigan Stephanie L , Kennedy Breandán N 
Published: May 2017

Background and PurposePathological growth of ocular vasculature networks can underpin visual impairment in neovascular age‐related macular degeneration, proliferative diabetic retinopathy and retinopathy of prematurity. Our aim was to uncover novel pharmacological regulators of ocular angiogenesis by phenotype‐based screening in zebrafish.Experimental ApproachA bioactive chemical library of 465 drugs was screened to identify small molecule inhibitors of ocular hyaloid vasculature (HV) angiogenesis in zebrafish larvae. Selectivity was assessed by evaluation of non‐ocular intersegmental vasculature development. Safety pharmacology examined visual behaviour and retinal histology in larvae. Molecular mechanisms of action were scrutinized using expression profiling of target mRNAs and miRNAs in larval eyes.Key ResultsLibrary screening identified 10 compounds which significantly inhibited HV developmental angiogenesis. The validated hit calcitriol selectively demonstrated dose‐dependent attenuation of HV development. In agreement, vitamin D receptor (VDR) agonists paricalcitol, doxercalciferol, maxacalcitol, calcipotriol, seocalcitol, calcifediol and tacalcitol significantly and selectively attenuated HV development. VDR agonists induced minor ocular morphology abnormalities and affected normal visual function. Calcitriol induced a three to sevenfold increase in ocular dre‐miR‐21 expression. Consistently, all‐trans‐retinoic acid attenuated HV development and increased ocular dre‐miR‐21 expression. Interestingly, zebrafish ocular vegfaa and vegfab expression was significantly increased while, vegfc, flt1 and kdrl expression was unchanged by calcitriol.Conclusion and ImplicationsThese studies identified VDR agonists as significant and selective anti‐angiogenics in the developing vertebrate eye and miR21 as a key downstream regulated miRNA. These targets should be further evaluated as molecular hallmarks of, and therapeutic targets for pathological ocular neovascularization.