bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Linear Optimization on Promotion Planning
Authors: Cohen Maxime C. , Leung Ngai-Hang Zachary , Panchamgam Kiran , Perakis Georgia , Smith Anthony 
Published: January 2017

Sales promotions are important in the fast-moving consumer goods (FMCG) industry due to the significant spending on promotions and the fact that a large proportion of FMCG products are sold on promotion. This paper considers the problem of planning sales promotions for an FMCG product in a grocery retail setting. The category manager has to solve the promotion optimization problem (POP) for each product, i.e., how to select a posted price for each period in a finite horizon so as to maximize the retailer’s profit. Through our collaboration with Oracle Retail, we developed an optimization formulation for the POP that can be used by category managers in a grocery environment. Our formulation incorporates business rules that are relevant, in practice. We propose general classes of demand functions (including multiplicative and additive), which incorporate the post-promotion dip effect, and can be estimated from sales data. In general, the POP formulation has a nonlinear objective and is NP-hard. We then propose a linear integer programming (IP) approximation of the POP. We show that the IP has an integral feasible region, and hence can be solved efficiently as a linear program (LP). We develop performance guarantees for the profit of the LP solution relative to the optimal profit. Using sales data from a grocery retailer, we first show that our demand models can be estimated with high accuracy, and then demonstrate that using the LP promotion schedule could potentially increase the profit by 3%, with a potential profit increase of 5% if some business constraints were to be relaxed. The online appendix is available at https://doi.org/10.1287/opre.2016.1573
Feasibility, acceptability, and tolerability of RGN107 in the palliative wound care management of chronic wound symptoms
Authors: Madisetti M. , Kelechi T.J. , Mueller M. , Amella E.J. , Prentice M.A. 
Published: January 2017

Objective: To assess the feasibility, acceptability and tolerability of RGN107 use, a natural powder blend of Arnica Montana, Calendula Officinalis, Mentha Arvensis and Santalum Album, among hospice patients and their wound caregivers in the palliative wound care management of chronic wound symptoms at end-of-life. Method: Data were collected between May 2013 and November 2015. A pilot trial conducted among 50 hospice patients with symptomatic (pain, odour, or exudate) chronic wounds. Caregivers received initial RGN107 protocol training, actively applied the powder to patient wounds for 4-weeks, and completed an 8-week retrospective survey. Feasibility was assessed by measuring process outcomes, including the number and proportion of participants referred, screened eligible, enrolled, withdrawn and successfully completed. Acceptability measures included: a protocol training evaluation, caregiver pre and post self-efficacy ratings, retrospective usability, symptom control management and comparative technique caregiver ratings, and recorded open-ended comments. Tolerability was assessed through a 12-week cumulative review of the study adverse event profile. Results: Feasibility, tolerability and acceptability of use of the RGN107 powder for chronic wounds were established. Recruitment goals were achieved and 92 % of the patients successfully completed the study. 95 % of wound caregivers would recommend the powder for use in this population. Conclusion: This study supports the feasibility, acceptability and tolerability of a wound care powder that espouses a multi-symptom palliative comfort care approach for hospice patients with chronic wounds at end-of-life. Further research is needed to establish the efficacy of the powder.
New Spectrophotometric Method for the Assay of Sulfadiazine Drug Based on Diazotization Coupling Reaction
Authors: Al-Rufaie Mohauman Mohammad 
Published: January 2017

Abstract
A sensitive, simple and rapid spectrophotometric procedure for the assay of trace quantities of sulfadiazine (SDZ) drug as bulk and in diluted solution is characterized. The procedure depends on the diazotization reaction which is produced by coupling SDZ with (4-amino-2-hydroxy acetophenon) (AHA) to produce an intense colored complex spectrophotometrically determined at 410 nm. Beer’s law was applied in the range of concentration 0.5 - 15 ppm; the molar absorptivity and Sandell’s sensitivity were 2.8484 × 104 L mol-1 cm-1 and 0.008 μg cm-2 respectively. The method limit of detection (LOD) was 0.443 μg mL-1 and LOQ (the method limit of quantitation) was 0.249 μg mL-1. The procedure is not based on solvent extraction and the additives and excipients do not significantly influence the developed procedure.
Multivariable predictive control considering time delay for load-frequency control in multi-area power systems
Authors: Daniar Sabah , Shiroei Mojtaba , Aazami Rahmat 
Published: January 2017

Abstract
In this paper, a multivariable model based predictive control (MPC) is proposed for the solution of load frequency control (LFC) in a multi-area interconnected power system. The proposed controller is designed to consider time delay, generation rate constraint and multivariable nature of the LFC system, simultaneously. A new formulation of the MPC is presented to compensate time delay. The generation rate constraint is considered by employing a constrained MPC and economic allocation of the generation is further guaranteed by an innovative modification in the predictive control objective function. The effectiveness of proposed scheme is verified through time-based simulations on the standard 39-bus test system and the responses are then compared with the proportional-integral controller. The evaluation of the results reveals that the proposed control scheme offers satisfactory performance with fast responses.
Analysis and comparison of the stability of discrete-time and continuous-time linear systems
Authors: Kaczorek Tadeusz 
Published: January 2017

Abstract
The asymptotic stability of discrete-time and continuous-time linear systems described by the equations xi+1 = Ākxi and x(t) = Akx(t) for k being integers and rational numbers is addressed. Necessary and sufficient conditions for the asymptotic stability of the systems are established. It is shown that: 1) the asymptotic stability of discrete-time systems depends only on the modules of the eigenvalues of matrix Āk and of the continuous-time systems depends only on phases of the eigenvalues of the matrix Ak, 2) the discrete-time systems are asymptotically stable for all admissible values of the discretization step if and only if the continuous-time systems are asymptotically stable, 3) the upper bound of the discretization step depends on the eigenvalues of the matrix A.
Reclassification of 21 Presumptive Canine Peripheral Nerve Sheath Tumors (PNST) Using a Literature-Based Immunohistochemical Panel
Authors: Sirri Rubina , Sabattini Silvia , Bettini Giuliano , Mandrioli Luciana 
Published: January 2017

AbstractThe aim of this study was to re-evaluate archived samples of canine soft tissue sarcomas (STSs) morphologically consistent with peripheral nerve sheath tumors (PNSTs). In each case, an immunohistochemical panel was applied, including α-SMA, calponin, desmin, S-100, GFAP, NSE and Olig2, in order to assess whether the phenotype was consistent with the tumor histological appearance. Additionally, the expression of EGFR, a marker with potential therapeutic implications in malignant PNSTs, was evaluated. Twenty-one tumors were included. Fourteen cases (66.7%) were positive for one or more muscular markers and were reclassified as perivascular tumors (PWTs). A positive labeling for S-100 was observed in one tumor (4.8%), thus classifi ed as PNST. The other 6 tumors were generically classified as poorly differentiated STSs. No unique histopathological feature was observed within the three groups. NSE and Olig2 labeling was aspecific and not useful for diagnostic purposes. GFAP was negative in all cases. Six cases (28.6%) were positive for EGFR, including the PNST. Even after the application of a wide immunohistochemical panel, distinguishing between PNSTs and PWTs remains a challenge. Finally, a subgroup of cases cannot be classified based on light microscopy alone.
The Technology and Structural Properties of Special Glass Modified (Ba0.6Pb0.4)TiO3 Ceramics
Authors: Wodecka-Dus B. , Adamczyk M. , Goryczka T. , Dzik J. , Radoszewska D. , Kozielski L. , Bochenek D. 
Published: January 2017

Abstract
The present paper widely describes the details of technology of (Ba0.6Pb0.4)TiO3 ceramics modified with PbO-B2O3-Al2O3-WO3 special glass, as well as the influence of admixture on the microstructure and crystal structure of basic material. The microstructure investigations reveal the significant increase of grain size and a decrease of pores participation in volume of modified samples, whereas the X-Ray Diffraction (XRD) measurements show a decrease of the volume of unit cell. The obtained results are discussed due to processes occurring during the sintering process at high temperature.
Corrosion Resistance of Titanium Based Composites Reinforced with in situ TiB Precipitation Phase
Authors: Miklaszewski A. 
Published: January 2017

Abstract
The paper presents the results of corrosion resistance tests carried out on titanium based composites reinforced with different TiB precipitation phase amount, dependent from boron addition in starting powder blends. Precursor powder preparation and processing parameters of conventional powder metallurgical approach influence density and obtained porosity of bulk compacts. The potentiodynamic tests performed in 0.1 M NaCl solution by the technique of linear voltammetry shows visible difference between compared composite structures. Studies have confirmed that the reinforcement phase amount and its morphology influence obtained microstructure and have important effect on the composite corrosion resistance.
The Analysis of Nitrogen Oxides Formation During Oxygen - Enriched Combustion of Natural Gas
Authors: Poskart A. , Radomiak H. , Niegodajew P. , Zajemska M. , Musiał D. 
Published: January 2017

Abstract
This paper presents the study of oxygen–enriched combustion of natural gas and its impact on nitrogen oxides emission. The research were performed on two experimental stands, i.e. combustion chambers with an industrial swirl burner of maximum power equal to 90 kW and 10 kW. The investigation includes the influenced of oxygen enhanced within the range between 21% and 30%. Furthermore, the role of temperature during the oxygen enrichment was analysed. The results of the research showed that with the rise in oxygen concentration in the air the concentration of nitrogen oxides also increases what is directly related to the rise in flame temperature as well as the addition of oxygen.
Numerical Simulation of Duplex Steel Multipass Welding
Authors: Giętka T. , Ciechacki K. , Kik T. 
Published: January 2017

Abstract
Analyses based on FEM calculations have significantly changed the possibilities of determining welding strains and stresses at early stages of product design and welding technology development. Such an approach to design enables obtaining significant savings in production preparation and post-weld deformation corrections and is also important for utility properties of welded joints obtained. As a result, it is possible to make changes to a simulated process before introducing them into real production as well as to test various variants of a given solution. Numerical simulations require the combination of problems of thermal, mechanical and metallurgical analysis. The study presented involved the SYSWELD software-based analysis of GMA welded multipass butt joints made of duplex steel sheets. The analysis of the distribution of stresses and displacements were carried out for typical welding procedure as during real welding tests.
Longevity Risk-Sharing Annuities: Partial Indexation in Mortality Experience
Authors: Zhang Saisai , Li Johnny Siu-Hang 
Published: January 2017

Abstract
In a conventional fixed annuity, idiosyncratic risk is diversified away while systematic longevity risk is borne entirely by the provider. The mortality-indexed annuity on the other hand, transfers systematic longevity risk completely back to the annuitants by fully adjusting benefits to mortality experience. In this paper, we propose the partial mortality-indexed annuity (PMIA), which aims to seek a balance between the two ends of the risk-sharing spectrum. Through a simulation study, we show that the PMIA achieves risk sharing and benefits both the provider and the annuitant.
Carotid Artery Disease - Left vs Right
Authors: Ionescu Ana-Maria , Carciumaru N. , Chirila S. 
Published: January 2017

Abstract
Stroke is a common cause of adult disability and the third cause of death in Western European countries. Carotid disease is a well-known risk factor for ischemic stroke, and this relationship is established. However, only a minority of the population with atherosclerosis will have a stroke.
The aim of these paper is to establish the relation between carotid atherosclerosis and first ischemic stroke. We performed an observational study, including 159 patients with carotid atherosclerosis. Our patients were examined with carotid ultrasound examination and cranio-cerebral computed tomography. We excluded patient with other cause of cerebral ischemia such atrial fibrillation, myocardial infarction, arterial dissection, vasculopathy, neoplasia. We also excluded any kind of transient cerebral ischemia, because of heterogeneity and poor medical documentation.
Despite our efforts to treat this condition, carotid disease remains a powerful risk factor for ischemic stroke.
Delayed vertebral diagnosed L4 pincer vertebral fracture, L2-L3 ruptured vertebral lumbar disc hernia, L5 vertebral wedge fracture - Case report
Authors: Balasa D , Schiopu M , Tunas A , Baz R , Hancu Anca 
Published: January 2017

Abstract
An association between delayed ruptured lumbar disc hernia, L5 vertebral wedge fracture and posttraumaticL4 pincer vertebral fracture (A2.3-AO clasification) at different levels is a very rare entity. We present the case of a 55 years old male who falled down from a bicycle. 2 months later because of intense and permanent vertebral lumbar and radicular L2 and L3 pain (Visual Scal Autologus of Pain7-8/10) the patient came to the hospital. He was diagnosed with pincer vertebral L4 fracture (A2.3-AO clasification) and L2-L3 right ruptured lumbar disc hernia in lateral reces. The patient was operated (L2-L3 right fenestration, and resection of lumbar disc hernia, bilateral stabilisation, L3-L4-L5 with titan screws and postero-lateral bone graft L4 bilateral harvested from iliac crest).
Self - inflicted lesions in children - indicator of intra familial abuse
Authors: Rebeleanu C , Mocanu Lacramioara , Popa M. 
Published: January 2017

Abstract
Self - inflicted lesions refers to a behavioural disorder with a complex ethiology. The occurrence of these cases in minors seems to be on the increase in last years, as well as minors abuse. On the assumption that there is a possible relation between minors abuse and this behavioural disorder, it has been evaluated comparatively the frequency with which it occurs among the minors examined in the forensic practice following reported abuse and the frequency with which it appears among the general population, sampled from the pupils in the final year of a high school in Bistrita.
Gradual and Cumulative Improvements to the Classical Differential Evolution Scheme through Experiments
Authors: Anescu George 
Published: January 2017

Abstract
The paper presents the experimental results of some tests conducted with the purpose to gradually and cumulatively improve the classical DE scheme in both efficiency and success rate. The modifications consisted in the randomization of the scaling factor (a simple jitter scheme), a more efficient Random Greedy Selection scheme, an adaptive scheme for the crossover probability and a resetting mechanism for the agents. After each modification step, experiments have been conducted on a set of 11 scalable, multimodal, continuous optimization functions in order to analyze the improvements and decide the new improvement direction. Finally, only the initial classical scheme and the constructed Fast Self-Adaptive DE (FSA-DE) variant were compared with the purpose of testing their performance degradation with the increase of the search space dimension. The experimental results demonstrated the superiority of the proposed FSA-DE variant.
Interleukin-33 plasma levels in patients with relapsing-remitting multiple sclerosis
Authors: Alsahebfosoul Fereshteh , Rahimmanesh Ilnaz , Shajarian Mansour , Etemadifar Masoud , Sedaghat Nahid , Hejazi Zahra , Naderi Shamsi 
Published: January 2017

Abstract
Cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS). Interleukin (IL)-33, one of the recently discovered members of the IL-1 superfamily, is a dual functional cytokine involved in various autoimmune disorders. In a case-control study, venous blood was collected from healthy subjects categorized as control group (n=44) and MS patients (n=44). All recruited patients were clinically diagnosed with relapsing-remitting MS (RRMS), including patients without treatment (new identified cases, n=16) and those treated with interferon beta (IFN-β) (n=28). The plasma levels of IL-33 in subjects were measured with ELISA. Significantly elevated IL-33 plasma levels were observed in RRMS patients (p=0.005). Furthermore, IFN-β-treated MS patients had lower levels of IL-33 compared to the untreated patients (p<0.001). Increased IL-33 plasma levels in the patient group might be associated with development of MS. These results could contribute to our better understanding about the role of IL-33 in the immunopathogenesis of MS.
Morphology of Sinophysis microcephala and Sinophysis canaliculata (Dinophyceae) from the South Atlantic Ocean
Authors: Diniz Bruna S. , Menezes Mariângela , Nascimento Silvia Mattos 
Published: January 2017

Abstract
The aim of this study was to describe the morphology of species of the benthic dinoflagellate genus Sinophysis from the tropical South Atlantic. Species were collected from four sampling sites and were identified based on light and epifluorescence microscopy. Sinophysis microcephala was found at three sites. Cells were elongated and oval in lateral view. Sinophysis canaliculata was recorded at two sites. Cells were round in lateral view and a short cut was present at the H2 plate. To the best of our knowledge, this is the first record of the genus Sinophysis from the South Atlantic Ocean.
Estuarine Distribution of Saprolegniaceae in the Tampa Bay Area: I
Authors: Wagner-Merner Diane Te 
Published: January 2017

AbstractA preliminary study determined the presence of some Saprolegniaceae in a small estuary in the Tampa Bay Area. Traditional methods of collecting aquatic fungi were employed. The results support the previously noted occurrence of these fungi and extend the geographical range of the species of tlus taxon. These and previously reported results of estuarine studies of Saprolegniaceae suggest that some species in this family are limited in their occurrence in southeastern United States estuaries.
Influence Coefficients of Constructive Parameters of Meander Slow-Wave System with Additional Shields
Authors: Metlevskis Edvardas , Martavičius Romanas , Katkevičius Andrius , Plonis Darius 
Published: January 2017

Abstract
Constructions of meander slow-wave systems with additional shields grounded at different positions are presented. The construction of meander slow-wave systems with additional shields grounded at both edges is investigated in detail. The influence of the main constructive parameters on the electrical characteristics of meander slow-wave systems with additional shields grounded at both edges is evaluated. The main constructive parameters of the investigated system are: the length of the conductor, the width of meander conductor, the width of additional shield, and the width of the gap between adjacent meander conductors.
Sonnet® software package, which is based on the method of moments, has been used during the investigation. The results of the influence of constructive parameters to the phase delay time, input impedance, and the width of pass-band of the system are discussed.
Measuring the Level of Competition on the Serbian Mobile Telecommunications Market
Authors: Kostić Zorana , Stojanović Boban , Radukić Snežana 
Published: January 2017

Abstract
The starting hypothesis is that the market structure to a large extent determines the conduct and the level of the achieved performance of economic entities. The aim of this paper is to determine the theoretical and empirical correlation between market structure, conduct, and performance of economic entities. The paper provides an analytical overview of the mobile telecommunications market in the Republic of Serbia. By using different indicators (the Concentration ratio, the HHI, the Lorenz curve, and the Gini coefficient), the supply concentration in this market is measured and the nature of competition is analysed. By using statistical methods (correlation and simple linear regression analysis), the correlation between the variables, which confirmed the existence of a strong positive correlation between the degree of supply concentration on the market and the level of achieved performance is examined.
The Impact Of Location On The Role Of Small Towns In Regional Development: Mazovia, Poland
Authors: Czapiewski Konrad , Bański Jerzy , Górczyńska Magdalena 
Published: January 2017

AbstractThe paper explores the role of small towns in the Mazovia region in Poland which is both characterized by rural areas and the suburban zone of Warsaw. The analysis of changes in the local labour markets reveals that microregions formed by small peripheral towns were more resistant to changes than those located in the suburban area of Warsaw. The latter were absorbed by the capital city whose zone of influence expanded in the detriment of adjacent small towns and their microregions. Using the concept of exogenous functions performed by small towns, we also shed light on their role with regard to the surrounding areas (with dominant agricultural function) in the past decade. The values of the service concentration index (SCI) and the level of population concentration showed that the majority of services to local and neighbouring inhabitants were delivered in small county towns located in the periphery. On the other hand, small county towns located in the vicinity of Warsaw mainly provided services to their inhabitants.
The Long-Term Impact of Price Controls in Medicare Part D
Authors: Moreno Gigi , van Eijndhoven Emma , Benner Jennifer , Sullivan Jeffrey 
Published: January 2017

Abstract
Price controls for prescription drugs are once again at the forefront of policy discussions in the United States. Much of the focus has been on the potential short-term savings – in terms of lower spending – although evidence suggests price controls can dampen innovation and adversely affect long-term population health. This paper applies the Health Economics Medical Innovation Simulation, a microsimulation of older Americans, to estimate the long-term impacts of government price setting in Medicare Part D, using pricing in the Federal Veterans Health Administration program as a proxy. We find that VA-style pricing policies would save between $0.1 trillion and $0.3 trillion (US$2015) in lifetime drug spending for people born in 1949–2005. However, such savings come with social costs. After accounting for innovation spillovers, we find that price setting in Part D reduces the number of new drug introductions by as much as 25% relative to the status quo. As a result, life expectancy for the cohort born in 1991–1995 is reduced by almost 2 years relative to the status quo. Overall, we find that price controls would reduce lifetime welfare by $5.7 to $13.3 trillion (US$2015) for the US population born in 1949–2005.