bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction Interval Estimation of Demand Curve in Electric Power Distribution System
Authors: YAMAZAKI TOMOHIDE , WAKAO SHINJI , ITO HIROKAZU , SANO TSUNEYO 
Published: September 2017

SUMMARYIn a distribution line, power system control and power equipment investment are planned based on a measured power system current. However, recently the mass introduction of photovoltaic (PV) make it difficult for us to precisely measure the demand curve that is a current consumed by electrical equipment because the reversal power flow from PV systems is superposed. Therefore, the prediction of demand curves of distribution line is indispensable for power system management. In addition, it is also necessary to estimate the reliability of the predicted values as well as predicted current itself. In this paper, we propose the estimation method of the prediction interval that is the index of reliability based on the past demand curve database. The feature of the proposed method based on Just‐In‐Time (JIT) modeling make it possible for us to accurately estimate the prediction interval by the normalized database of demand curve. In this paper, some numerical examples are presented, which demonstrate the effectiveness of the proposed method.
Determination of Quercetin and Luteolin in Paprika Samples by Voltammetry and Partial Least Squares Calibration
Authors: Chamizo‐González Francisco , Monago‐Maraña Olga , Galeano‐Díaz Teresa 
Published: September 2017

AbstractQuercetin and luteolin are flavonoids with beneficious properties, which are present in paprika. In this work, both have been determined in paprika by using electrochemistry combined with chemometrics. The electrochemical oxidation mechanisms of both analytes have been studied through sampled direct current (DC) voltammetry, differential pulse voltammetry (DPV) and Square Wave Voltammetry (SWV), making use of a glassy carbon electrode. The final technique selected for the quantification was DPV due to its high repeatability with respect SWV. The chemical variables and the instrumental parameters were optimized and the final conditions employed were ethanol: water (20 : 80), 0.75 mol dm−3 of HCl, and a pulse amplitude of 50 mV. Due to the facts that oxidation potential of both analytes were quite similar, their DPV peaks were overlapped, and also because the analytes interaction during the electrochemical process causes a non‐additivity of the signals, they could not be quantified separately by direct measurement of peak intensity. For this reason, a chemometric algorithm was applied (partial least squares (PLS) regression in its modality PLS‐2). In the case of validation samples, appropriate sets of calibration and validation were built and good results were obtained. This methodology was applied to real paprika samples and the results were similar to those obtained with a HPLC method previously reported.
Organic polymer‐based monolithic stationary phases with incorporated nanostructured materials for HPLC and CEC
Authors: Ganewatta Nisansala , El Rassi Ziad 
Published: September 2017

AbstractThis review article is concerned with the recent advances made in the field of organic polymer‐based monoliths with incorporated nanostructured materials (NSMs) for use in liquid chromatography and capillary electrochromatography. It covers the pertinent literature published over the last 7–8 years with a total of 56 references. The present article has two distinct parts: one major part encompassing “traditional” organic polymer‐based monoliths modified with NSMs and a minor part on cryogels modified with NSMs.
Pedagogical Principles of Evaluation: Interpreting Freire
Authors: Patton Michael Quinn 
Published: September 2017

AbstractPedagogy of evaluation entails examining how and what evaluation teaches. Embedded in different evaluation approaches are varying assumptions, values, premises, priorities, sense‐making processes, and principles. Elucidating and illuminating principles is fundamental to identifying and understanding a pedagogy of evaluation. Ten pedagogical principles from Paulo Freire's writings are identified and explained. Each principle is then examined for its relevance to a critical pedagogy of evaluation for evaluation theory and practice today and looking forward. Freire understood and taught us that all interactions between and among people are pedagogical, something is always being taught, conveyed, and proselytized. Extending this insight to evaluation, Freire's work reminds us that all evaluation approaches constitute a pedagogy of some kind. What any particular evaluation teaches and how it is taught varies, but evaluation is inherently and predominantly a pedagogical interaction. This leads to the concluding question: What is your pedagogy of evaluation?
The association between insulin resistance, metabolic variables, and depressive symptoms in Mexican‐American elderly: A population‐based study
Authors: Diniz Breno S. , Fisher‐Hoch Susan , McCormick Joseph 
Published: September 2017

ObjectiveDepressive symptoms are common among older adults with obesity and diabetes. Nonetheless, the mechanisms for this association are not clear but may involve changes in the insulin cascade signaling. We aimed to investigate the association, and potential mediators, between obesity, insulin resistance, and depressive symptoms among older adults from a homogenous cohort of Mexican‐Americans.MethodsWe included a total of 500 Mexican‐American older adults assessed in the Cameron County Health Study. We evaluated depressive symptoms using the Center for Epidemiologic Survey Depression Scale (CES‐D). Central obesity was defined by waist circumference. Insulin resistance was evaluated by the HOMA‐IR index. We estimated the association between obesity, insulin resistance, and depressive symptoms by carrying out univariate and multivariate regression analyses.ResultsIn unadjusted regression analysis, HOMA‐IR (unstandardized β = 0.31 ± 0.12, P = 0.007), waist circumference (unstandardized β = 0.066 ± 0.0.028, P = 0.017), and Hb1Ac levels (unstandardized β = 0.52 ± 0.24, P = 0.03) were significantly associated with CES‐D scores. The association of HOMA‐IR and CES‐D remained statistically significant after controlling for socio‐demographic and clinical variables in multivariate analysis (unstandardized β = 0.28 ± 0.11, P = 0.01).ConclusionOur results suggest that depressive symptoms are associated with insulin resistance in older Mexican‐American adults. In addition, poorer glucose control and obesity are important mediators of this relationship. Additional studies are needed to evaluate whether interventions that increase insulin sensitivity can also reduce depressive symptoms in this population.
Evidence‐based source modeling of nociceptive cortical responses: A direct comparison of scalp and intracranial activity in humans
Authors: Bradley Claire , Bastuji Hélène , Garcia‐Larrea Luis 
Published: September 2017

AbstractBackgroundSource modeling of EEG traditionally relies on interplay between physiological hypotheses and mathematical estimates. We propose to optimize the process by using evidence gathered from brain imaging and intracortical recordings.MethodsWe recorded laser‐evoked potentials in 18 healthy participants, using high‐density EEG. Brain sources were modeled during the first second poststimulus, constraining their initial position to regions where nociceptive‐related activity has been ascertained by intracranial EEG. These comprised the two posterior operculo‐insular regions, primary sensorimotor, posterior parietal, anterior cingulate/supplementary motor (ACC/SMA), bilateral frontal/anterior insular, and posterior cingulate (PCC) cortices.ResultsThe model yielded an average goodness of fit of 91% for individual and 95.8% for grand‐average data. When compared with intracranial recordings from 27 human subjects, no significant difference in peak latencies was observed between modeled and intracranial data for 5 of the 6 assessable regions. Morphological match was excellent for operculo‐insular, frontal, ACC/SMA and PCC regions (cross‐correlation > 0.7) and fair for sensori‐motor and posterior parietal cortex (c‐c ∼ 0.5).ConclusionsMultiple overlapping activities evoked by nociceptive input can be disentangled from high‐density scalp EEG guided by intracranial data. Modeled sources accurately described the timing and morphology of most activities recorded with intracranial electrodes, including those coinciding with the emergence of stimulus awareness. Hum Brain Mapp 38:6083–6095, 2017. © 2017 Wiley Periodicals, Inc.
A CRISPR reimagining: New twists and turns of CRISPR beyond the genome‐engineering revolution
Authors: Plummer Robert J. , Guo Yi , Peng Ying 
Published: September 2017

AbstractDespite its explosive applications in genome engineering, CRISPR (Clustered Regularly Interspersed Short Palindromic Repeats) has been developed into a versatile tool beyond its well‐known nuclease function. In this prospect article, we summarize a few exciting “off‐label” applications of CRISPR including manipulating DNA sequences, visualizing chromosomal loci in living cells, and modulating transcription and chromatin structures. These novel applications will likely elevate CRISPR tools into yet another level of sophistication and diversity, leading to many more exciting cell biological discoveries.
Radiomics signature: A potential biomarker for the prediction of MGMT promoter methylation in glioblastoma
Authors: Xi Yi‐bin , Guo Fan , Xu Zi‐liang , Li Chen , Wei Wei , Tian Ping , Liu Ting‐ting , Liu Lin , Chen Gang , Ye Jing , Cheng Guang , Cui Long‐biao , Zhang Hong‐juan , Qin Wei , Yin Hong 
Published: September 2017

BackgroundIn glioblastoma (GBM), promoter methylation of the DNA repair gene O‐methylguanine‐DNA methyltransferase (MGMT) is associated with beneficial chemotherapy.Purpose/HypothesisTo analyze radiomics features for utilizing the full potential of medical imaging as biomarkers of MGMT promoter methylation.Study TypeRetrospective.Population/SubjectsIn all, 98 GBM patients with known MGMT (48 methylated and 50 unmethylated tumors).Field Strength/Sequence3.0T magnetic resonance (MR) images, containing T1‐weighted image (T1WI), T2‐weighted image (T2WI), and enhanced T1WI.AssessmentA region of interest (ROI) of the tumor was delineated. A total of 1665 radiomics features were extracted and quantized, and were reduced using least absolute shrinkage and selection operator (LASSO) regularization.Statistical TestingAfter the support vector machine construction, accuracy, sensitivity, and specificity were computed for different sequences. An independent validation cohort containing 20 GBM patients was utilized to further evaluate the radiomics model performance.ResultsRadiomics features of T1WI reached an accuracy of 67.54%. Enhanced T1WI features reached an accuracy of 82.01%, while T2WI reached an accuracy of 69.25%. The best classification system for predicting MGMT promoter methylation status originated from the combination of 36 T1WI, T2WI, and enhanced T1WI images features, with an accuracy of 86.59%. Further validation on the independent cohort of 20 patients produced similar results, with an accuracy of 80%.Data ConclusionOur results provide further evidence that radiomics MR features could predict MGMT methylation status in preoperative GBM. Multiple imaging modalities together can yield putative noninvasive biomarkers for the identification of MGMT.Level of Evidence: 4Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:1380–1387.
Ionic liquids: solvents and sorbents in sample preparation
Authors: Clark Kevin D. , Emaus Miranda N. , Varona Marcelino , Bowers Ashley N. , Anderson Jared L. 
Published: September 2017

AbstractThe applications of ionic liquids (ILs) and IL‐derived sorbents are rapidly expanding. By careful selection of the cation and anion components, the physicochemical properties of ILs can be altered to meet the requirements of specific applications. Reports of IL solvents possessing high selectivity for specific analytes are numerous and continue to motivate the development of new IL‐based sample preparation methods that are faster, more selective, and environmentally benign compared to conventional organic solvents. The advantages of ILs have also been exploited in solid/polymer formats in which ordinarily nonspecific sorbents are functionalized with IL moieties in order to impart selectivity for an analyte or analyte class. Furthermore, new ILs that incorporate a paramagnetic component into the IL structure, known as magnetic ionic liquids (MILs), have emerged as useful solvents for bioanalytical applications. In this rapidly changing field, this Review focuses on the applications of ILs and IL‐based sorbents in sample preparation with a special emphasis on liquid phase extraction techniques using ILs and MILs, IL‐based solid‐phase extraction, ILs in mass spectrometry, and biological applications.
The metabolic cross‐talk between epithelial cancer cells and stromal fibroblasts in ovarian cancer progression: Autophagy plays a role
Authors: Thuwajit Chanitra , Ferraresi Alessandra , Titone Rossella , Thuwajit Peti , Isidoro Ciro 
Published: September 2017

AbstractCancer and stromal cells, which include (cancer‐associated) fibroblasts, adipocytes, and immune cells, constitute a mixed cellular ecosystem that dynamically influences the behavior of each component, creating conditions that ultimately favor the emergence of malignant clones. Ovarian cancer cells release cytokines that recruit and activate stromal fibroblasts and immune cells, so perpetuating a state of inflammation in the stroma that hampers the immune response and facilitates cancer survival and propagation. Further, the stroma vasculature impacts the metabolism of the cells by providing or limiting the availability of oxygen and nutrients. Autophagy, a lysosomal catabolic process with homeostatic and prosurvival functions, influences the behavior of cancer cells, affecting a variety of processes such as the survival in metabolic harsh conditions, the invasive growth, the development of immune and chemo resistance, the maintenance of stem‐like properties, and dormancy. Further, autophagy is involved in the secretion and the signaling of promigratory cytokines. Cancer‐associated fibroblasts can influence the actual level of autophagy in ovarian cancer cells through the secretion of pro‐inflammatory cytokines and the release of autophagy‐derived metabolites and substrates. Interrupting the metabolic cross‐talk between cancer cells and cancer‐associated fibroblasts could be an effective therapeutic strategy to arrest the progression and prevent the relapse of ovarian cancer.
Suprafascial dissection of the pedicled groin flap: A safe and practical approach to flap harvest
Authors: Abdelrahman Mohamed , Zelken Jonathan , Huang Ren‐Wen , Hsu Chung‐Chen , Lin Chih‐Hung , Lin Yu‐Te , Lin Cheng‐Hung 
Published: September 2017

AbstractBackgroundThe groin flap has been relied upon for more than 4 decades and is well suited for reconstruction of the mutilated hand. Classic groin flap harvest is subfascial and includes the superficial circumflex iliac artery (SCIA). SCIA perforator flaps have shown that one perforator is sufficient to supply a large flap without breaching fascia. Accordingly, we routinely preserve the fascia and rely wholly on the superficial branch of the SCIA, sparing the deep branch. We aim to investigate the safety of suprafascial flap elevation and encourage a paradigm shift in reconstruction with groin flap transfer.MethodsBetween 2008 and 2013, 77 hand injuries were treated with pedicled groin flap transfers. According to surgeons' preference, 49 flaps were elevated with conventional technique (“subfascial”) and 28 were harvested with suprafascial approach (“fascia sparing”). Demographic data including flap size, operative time, and outcome were reviewed in both approaches and compared.ResultsSuprafascial flaps were taken as large as 32 × 12 cm2 and subfascial flaps large as 30 × 10 cm2 (p = 0.08). Operative time was 268.2 ± 104.7 minutes in the suprafascial group and 227.4 ± 89.0 in the subfascial group (p = 0.14). One suprafascial flap (3.6%) had partial necrosis compared to four subfascial flaps (8.2%) (p = 0.65). All patients were followed for a minimum of six months. All the wounds finally healed without further flap reconstruction, and all the patients were back to the normal life with activities.ConclusionSuprafascial dissection is safe and does not adversely influence outcomes. Thinner flaps are expected to facilitate flap insetting and reduce revisionary debulking surgery.Level of EvidenceIII (Therapeutic)
Region‐specific impairment of the cervical spinal cord (SC) in amyotrophic lateral sclerosis: A preliminary study using SC templates and quantitative MRI (diffusion tensor imaging/inhomogeneous magnetization transfer)
Authors: Rasoanandrianina Henitsoa , Grapperon Aude‐Marie , Taso Manuel , Girard Olivier M. , Duhamel Guillaume , Guye Maxime , Ranjeva Jean‐Philippe , Attarian Shahram , Verschueren Annie , Callot Virginie 
Published: September 2017

In this preliminary study, our objective was to investigate the potential of high‐resolution anatomical imaging, diffusion tensor imaging (DTI) and conventional/inhomogeneous magnetization transfer imaging [magnetization transfer (MT)/inhomogeneous magnetization transfer (ihMT)] at 3 T, analyzed with template‐extracted regions of interest, to measure the atrophy and structural changes of white (WM) and gray (GM) matter spinal cord (SC) occurring in patients with amyotrophic lateral sclerosis (ALS). Ten patients with ALS and 20 age‐matched healthy controls were recruited. SC GM and WM areas were automatically segmented using dedicated templates. Atrophy indices were evaluated from T2*‐weighted images at each vertebral level from cervical C1 to C6. DTI and ihMT metrics were quantified within the corticospinal tract (CST), posterior sensory tract (PST) and anterior GM (aGM) horns at the C2 and C5 levels. Clinical disabilities of patients with ALS were evaluated using the Revised ALS Functional Rating Scale, upper motor neuron (UMN) and Medical Research Council scorings, and correlated with MR metrics. Compared with healthy controls, GM and WM atrophy was observed in patients with ALS, especially at lower cervical levels, where a strong correlation was also observed between GM atrophy and the UMN score (R = −0.75, p = 0.05 at C6). Interestingly, a significant decrease in ihMT ratio was found in all regions of interest (p < 0.0008), fractional anisotropy (FA) and MT ratios decreased significantly in CST, especially at C5 (p < 0.005), and λ// (axial diffusivity) decreased significantly in CST (p = 0.0004) and PST (p = 0.003) at C2. Strong correlations between MRI metrics and clinical scores were also found (0.47 < |R| < 0.87, p < 0.05). Altogether, these preliminary results suggest that high‐resolution anatomical imaging and ihMT imaging, in addition to DTI, are valuable for the characterization of SC tissue impairment in ALS. In this study, in addition to an important SC WM demyelination, we also observed, for the first time in ALS, impairments of cervical aGM.
Local and global properties of the harmonic polynomial cell method: In‐depth analysis in two dimensions
Authors: Ma S. , Hanssen F.‐C. W. , Siddiqui M. A. , Greco M. , Faltinsen O. M. 
Published: September 2017

AbstractA detailed and systematic analysis is performed on the local and global properties of the recently developed harmonic polynomial cell (HPC) method, a very accurate and efficient field solver for problems governed by the Laplace equation. At the local cell level, a simple rule is identified for the proper choice of harmonic polynomials in the local representation of the velocity potential in cells with symmetry properties. The local solution error, its convergence rate, its dependence on the cell topology, its distribution inside the cell, and its features across cells with different dimensions are carefully examined with relevant findings for HPC numerical implementations. At the global level, the error convergence rate is analytically estimated in terms of error contributions from the boundary conditions and from inside the liquid domain. In most cases, the error associated with boundary conditions dominates the global error. In order to minimize it, Quadtree grid strategies or high‐order local expressions of the velocity potential are proposed for cells near critical boundary portions. To model accurately the boundary conditions on rigid or deformable surfaces with generic geometries, 3 different grid strategies are proposed by adopting concepts of immersed boundary method and overlapping grids. They are comparatively studied for a circular rigid cylinder in infinite fluid and for the propagation of a free‐surface wave. Then, an immersed boundary strategy, using numerical choices suggested in this paper, is successfully compared against a fully nonlinear boundary element method for the case of a surface‐piercing circular cylinder heaving in otherwise calm water.
Modeling of uncertainty for flood wave propagation induced by variations in initial and boundary conditions using expectation operator on explicit numerical solutions
Authors: Wu Shiang‐Jen , Hsu Chih‐Tsung 
Published: September 2017

AbstractThis study proposes a framework for uncertainty analysis by incorporating explicit numerical solutions of governing equations for flood wave propagation with the expectation operator. It aims at effectively evaluating the effect of variations in initial and boundary conditions on the estimation of flood waves. Spatiotemporal semivariogram models are employed to quantify the correlation of the variables in time and space. The 1D nonlinear kinematic wave equation for the overland flow (named EVO_NS_KWE) is applied in the model development. Model validation is made by comparison with the Monte Carlo simulation model in the calculation of statistical properties of model outputs (ie, flow depths), that is, the mean, standard deviation, and coefficient of variation. The results from the model validation show that the EVO_NS_KWE model can produce excellent approximations of the mean and less satisfactory approximations of the standard deviation and coefficient of variation compared with those obtained by using the Monte Carlo simulation model. It concludes that the uncertainties of flow depths in the domain are significantly affected by variations in the boundary condition. Future application of the EVO_NS_KWE model enables the evaluation of uncertainty in model outputs induced by the initial and boundary condition subject to uncertainty and will also provide corresponding probabilistic information for risk quantification method.
Latino immigrant parents’ financial stress, depression, and academic involvement predicting child academic success
Authors: Gilbert Lauren R. , Spears Brown Christia , Mistry Rashmita S. 
Published: September 2017

AbstractThe current study examines Mexican‐heritage immigrant parents’ financial stress, English language fluency, and depressive symptoms as risk factors for parental academic involvement and child academic outcomes. Participants were 68 Latino immigrant (from Mexico) third and fourth graders and their parents. Results from a structural equation model analysis indicated that Latino parents who reported greater financial stress also reported higher levels of depressive symptoms; this, in turn, was related to lower parent‐reported levels of engagement in the monitoring and transmission of implicit and explicit valuing of academics. Parental monitoring of academics was positively associated with children's success in mathematics and transmission of implicit and explicit valuing of academics was positively associated with children's success in language arts. The current study extends support for the Family Economic Stress Model by demonstrating connections between parental stress, emotional well‐being, and child academic outcomes, through parental involvement in children's academics in a Latino‐heritage sample.