bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumer devotion to a different height
Authors: Hassan Mahmud , Casaló Ariño Luis V. 
Published: July 2016

Purpose
– Effective handling of negative word of mouth in the social media has dramatic impact on customer retention, deflects potential damage and improves profitability. Although marketers enact various defensive strategies to combat such negative publicity, consumers are increasingly acting on behalf of marketers and new value creating behaviors are noticed within virtual brand communities. The purpose of this paper is to explore the kind of consumers’ defensive behaviors present within Facebook brand communities (FBCs).

Design/methodology/approach
– A netnographic approach guided the data collection. Data were gathered by downloading messages; only the threads related to member’s defensive behaviors were downloaded and archived. This resulted to 34 pages of data with 418 individual comments and 6,257 words in total.

Findings
– Data reveals that defensive behavior is practiced within Facebook, noticing that more diverse types of defensive behaviors are practiced in high involved products. Also, defensive behaviors are more prevalent within utilitarian rather than hedonic brands.

Research limitations/implications
– This study suggests that marketers should be open to engage and empower consumers to fulfill the role of defending the brand within brand communities first.

Originality/value
– This work adds to previous literature on handling complaints in social media by analyzing how devoted consumers may defend the brand against negative remarks done by other consumers in FBCs. This study not only confirms that defensive behaviors are apparent within the eight FBCs considered, but also investigates possible differences between high and low involved brands and also utilitarian and hedonic brands.
Is a most helpful eWOM review really helpful? The impact of conflicting aggregate valence and consumer’s goals on product attitude
Authors: López-López Inés , Parra José Francisco 
Published: July 2016

Purpose– The purpose of this paper is to analyze the effect of signaling a review as the most helpful review according to other users’ votes on product attitude. Thus, the first study focuses on the influence of signaling a review as the most helpful on consumer attitude and analyzes whether the interaction between that signaled review and incongruent aggregate information in valence clarify the main effect. Additionally, the authors further investigate whether the level of fit between the consumer’s goals and the content of the signaled review moderates the initial effect.Design/methodology/approach– The authors conducted two experiments: a 3 (presence of most helpful review) × 2 (overall valence) between-subjects design and a 2 (presence of a most helpful review) × 3 (level of fit between the consumers’ goals and the most helpful review content) × 2 (overall valence) design.Findings– The results confirm that the presence of a “most helpful” review whose valence is incongruent with the overall valence of the reviews significantly impacts attitude towards the product. Specifically, the authors found that the impact of a review which has been voted as the most helpful on consumers’ attitudes depends on: the congruity between the valence of the most helpful review and the overall average valence of all the reviews received by the product; and the congruity between the consumer’s goals and the most helpful review content.Originality/value– This paper contributes to the electronic WOM literature by examining how signaling a review as the most helpful affects attitude, being that effect moderated by the congruency between that signaled review and the aggregated overall valence of the reviews and the level of fit with the consumer’s goals.
European REITs NAV discount: do investors believe in property appraisal?
Authors: Morri Giacomo , Baccarin Alessandro 
Published: July 2016

Purpose– The purpose of this paper is to analyse the NAV discount of European REITs listed in France, the Netherlands and the UK between 2003 and 2014, considering elements of both “rational” and “noise trader” approaches.Design/methodology/approach– The analysis examines the hypothesis that discounts (premiums) are the result of leverage, size, liquidity, risk, performance, investment activity and sentiment. The regressions are initially run against the traditional NAV discount, subsequently using the unlevered NAV discount measure introduced by Morriet al.(2005) in order to clean out the bias generated by the level of leverage. The NAV discount is then adjusted for investor sentiment (appraisal reduction) with the aim of better identifying firm-specific factors, considering distortions induced by sentiment.Findings– Higher liquidity commands lower discounts for French REITs, while Dutch and British REITs, which trade in markets characterized by a higher number of average daily transactions, do not seem to feature discounts resulting from liquidity. For all three samples, operational risk and performance are significant in explaining the NAV discount, the former having a positive relationship with the discount, and the latter a negative one. When measured using the average sector discount, sentiment has a profound effect on the discount, accounting alone for 10-15 per cent of the explanatory power of the model.Practical implications– REITs listed in different markets behave differently. When the discount is adjusted in order to remove the bias resulting from the level of debt, the relationship between leverage and the unlevered discount becomes less pronounced in all cases.Originality/value– The paper considers a new approach to NAV discount puzzle that takes into account market sentiment and appraisals.
Consistent alleviation of abiotic stress with silicon addition: a meta‐analysis
Authors: Cooke Julia , Leishman Michelle R. 
Published: July 2016

Summary

Hundreds of single species studies have demonstrated the facility of silicon (Si) to alleviate diverse abiotic stresses in plants. Understanding of the mechanisms of Si‐mediated stress alleviation is progressing, and several reviews have brought information together. A quantitative assessment of the alleviative capacity of Si, however, which could elucidate plant Si function more broadly, was lacking.

We combined the results of 145 experiments, predominantly on agricultural species, in a meta‐analysis to statistically assess the responses of stressed plants to Si supply across multiple plant families and abiotic stresses. We interrogated our database to determine whether stressed plants increased in dry mass and net assimilation rate, oxidative stress markers were reduced, antioxidant responses were increased and whether element uptake showed consistent changes when supplied with Si.

We demonstrated that across plant families and stress types, Si increases dry weight, assimilation rate and chlorophyll biosynthesis and alleviates oxidative damage in stressed plants. In general, results indicated that plant family (as a proxy for accumulator type) and stress type had significant explanatory power for variation in responses. The consistent reduction in oxidative damage was not mirrored by consistent increases in antioxidant production, indicative of the several different stress alleviation mechanisms in which Si is involved. Silicon addition increased K in shoots, decreased As and Cd in roots and Na and Cd in shoots. Silicon addition did not affect Al, Ca or Mn concentration in shoots and roots of stressed plants. Plants had significantly lower concentrations of Si accumulated in shoots but not in roots when stressed.

Meta‐analyses showed consistent alleviation by Si of oxidative damage caused by a range of abiotic stresses across diverse species. Our findings indicate that Si is likely to be a useful fertilizer for many crops facing a spectrum of abiotic stresses. Similarities in responses across families provide strong support for a role of Si in the alleviation of abiotic stress in natural systems, where it has barely been explored. We suggest this role may become more important under a changing climate and more experiments using non‐agricultural species are now needed.
Modeling the Growth of Epiphytic Bacteria on Kale Treated by Thermosonication Combined with Slightly Acidic Electrolyzed Water and Stored under Dynamic Temperature Conditions
Authors: Mansur Ahmad Rois , Oh Deog‐Hwan 
Published: July 2016

AbstractThe growth of epiphytic bacteria (aerobic mesophilic bacteria or Pseudomonas spp.) on kale was modeled isothermally and validated under dynamic storage temperatures. Each bacterial count on kale stored at isothermal conditions (4 to 25 °C) was recorded. The results show that maximum growth rate (μmax) of both epiphytic bacteria increased and lag time (λ) decreased with increasing temperature (P < 0.05). The maximum population density (Nmax) of Pseudomonas spp. was significantly greater than that of aerobic mesophilic bacteria, particularly in treated samples and/or at 4 and 10 °C (P < 0.05). The relationship between μmax of both epiphytic bacteria and temperature was linear (R2 > 0.97), whereas lower R2 > 0.86 and R2 > 0.87 was observed for the λ and Nmax, respectively. The overall predictions of both epiphytic bacterial growths under nonisothermal conditions with temperature abuse of 15 °C agreed with the observed data, whereas those with temperature abuse of 25 °C were greatly overestimated. The appropriate parameter q0 (physiological state of cells), therefore, was adjusted by a trial and error to fit the model. This study demonstrates that the developed model was able to predict accurately epiphytic bacterial growth on kale stored under nonisothermal conditions particularly those with low temperature abuse of 15 °C.
The Physician‐as‐Stakeholder: An Exploratory Qualitative Analysis of Physicians’ Motivations for Using Shared Decision Making in the Emergency Department
Authors: Schoenfeld Elizabeth M. , Goff Sarah L. , Elia Tala R. , Khordipour Errel R. , Poronsky Kye E. , Nault Kelly A. , Lindenauer Peter K. , Mazor Kathleen M. 
Published: July 2016

AbstractBackgroundShared decision making (SDM) is increasingly recognized as an important facet of patient‐centered care. Despite growing interest in SDM in the emergency department (ED), little is known about emergency physicians’ (EPs’) motivations for using SDM. Understanding current patterns of SDM use and EP's rationale for using SDM is essential for the development of interventions to increase use.ObjectivesRecognizing the EP as an important stakeholder in SDM research, we sought to identify and explore factors that may motivate EPs’ engagement in SDM.MethodsIn this qualitative study, informed by the Theory of Planned Behavior and Social Cognitive Theory, we conducted semistructured interviews with a purposeful sample of EPs. Interviews were recorded and transcribed verbatim. Using a directed qualitative content analysis approach, three members of the research team performed open coding of the transcripts in an iterative process, building a provisional code book as coding progressed. Respondent validation was employed to ensure methodologic rigor.ResultsFifteen EPs, ages 31–65, from both academic and community practice settings, were interviewed. Several had not heard of the specific phrase “shared decision making,” but all understood the concept and felt that they used SDM techniques to some degree. Most noted they had often had an agenda when they used SDM, which often motivated them to have the conversation. Agendas described included counteracting an algorithmic or defensive approach to diagnosis and treatment, avoiding harmful tests, or sharing uncertainty. All participants believed that patients benefited from SDM in terms of satisfaction, engagement, or education. Nearly all participants identified research outcomes that they felt would encourage their use of SDM (e.g., improvements in patient engagement, mitigation of risk) and many prioritized patient‐centered outcomes over systems outcomes such as improved resource utilization. Little consensus was seen, however, regarding the importance of individual outcomes: of eight potential research outcomes participants endorsed, no single outcome was endorsed by even half of the physicians interviewed.ConclusionEmergency physicians identified many factors that motivated them to use SDM. This study informs current research on SDM in the ED, particularly regarding the motivations of the physician‐as‐stakeholder.
Review of the clinical significance of respiratory virus infections in newborn infants
Authors: Luoto Raakel , Jartti Tuomas , Ruuskanen Olli , Waris Matti , Lehtonen Liisa , Heikkinen Terho 
Published: July 2016

AbstractRespiratory viruses have been recognised as causative agents for a wide spectrum of clinical manifestations and severe respiratory compromise in neonates during birth hospitalisation. Early‐life respiratory virus infections have also been shown to be associated with adverse long‐term consequences.ConclusionPreventing virus infections by intensifying hygiene measures and cohorting infected infants should be a major goal for neonatal intensive care units, as well as more common use of virus diagnostics. Active virus surveillance and long‐term follow‐up are needed to ascertain the causality and exact underlying mechanisms for adverse long‐term consequences.
Abnormal spermatogenesis and male infertility in testicular zinc finger protein Zfp318‐knockout mice
Authors: Ishizuka Masamichi , Ohtsuka Eri , Inoue Atsuto , Odaka Mirei , Ohshima Hirotaka , Tamura Norihisa , Yoshida Kaoru , Sako Norihisa , Baba Tadashi , Kashiwabara Shin‐ichi , Okabe Masaru , Noguchi Junko , Hagiwara Hiromi 
Published: July 2016

Zfp318, a mouse gene with a Cys2/His2 zinc finger motif, is mainly expressed in germ cells in the testis. It encodes two alternative transcripts, which regulate androgen receptor‐mediated transcriptional activation or repression by overexpression of them. However, the role of Zfp318 is still obscure in vivo, especially in spermatogenesis. To elucidate the role of Zfp318 during gamete production, we established a knockout mouse line. Zfp318‐null male mice exhibited infertility, whereas Zfp318‐null female mice displayed normal fertility. ZFP318 was expressed during multiple stages of spermatogenesis, from spermatocytes to round spermatids. The nuclei of secondary spermatocytes showed high levels of expression. Histological analysis and quantitative analysis of DNA content showed decreased numbers of both spermatids in the seminiferous tubules and mature spermatozoa in the epididymides of Zfp318‐null mice. These results suggest that Zfp318 is expressed as a functional protein in testicular germ cells and plays an important role in meiosis during spermatogenesis.
Transnasal Endoscopic Biopsy Approach to Atlas Tumor with X‐ray Assisted and Related Radiographic Measure
Authors: Li Zhen‐feng , Shao Xian‐hao , Zhang Li‐qiang , Yang Zhi‐ping , Li Xin , Yang Qiang , Li Jian‐min 
Published: July 2016

ObjectiveTo develop an endoscopic transnasal approach to atlas tumors and study its practicability.MethodsThis article comprises two components: an illustrative case report and observational data on 50 volunteers. As to the case report, a 34 year old man presented with occipital pain for more than 3 months and underwent systematic investigation in Qilu Hospital of Shandong University. CT and MRI scans showed bony destruction in the craniovertebral junction (CVJ) suggestive of tumor. Via an endoscopic transnasal approach to the suspected atlas tumor through the inferior nasal meatus, a Gallini biopsy needle was used to obtain tissue for examination. The procedure was performed endoscopically with double orientation X‐ray guidance and coaxial technology after establishing the shortest distance for the biopsy track and range of target tissue and was assisted by manual palpation. As to the observational data, 50 volunteers underwent atlas‐related morphometric image measurement using gemstone CT equipment. Biopsy track angles, range for biopsy of the atlas and biopsy track distances were measured by a blinded operator on CT images.ResultsCase report: pathological examination of the biopsy resulted in diagnosis of a chordoma. There were no complications such as bleeding, infection or spinal cord injury. One month later, the patient underwent tumor resection and reconstruction in other hospital and the diagnosis of chordoma was confirmed by pathological examination of the resected specimen. Observational data: measurements obtained from CT scans of the 50 volunteers were as follows. Biopsy track angles: mean leaning inside angle 3.53° ± 0.39° and mean posterior slope angle 13.05° ± 1.39°. Range for atlas biopsy: transverse diameter 11.84 ± 1.24 mm and longitudinal diameter 9.67 ± 0.90 mm. Biopsy track distances: from atlas to nostril, and to anterior and posterior edges of the inferior turbinate mucosa were 94.52 ± 5.03 mm, 78.21 ± 4.63 mm, and 33.51 ± 3.13 mm, respectively.ConclusionsAn endoscopic transnasal approach enables biopsy and diagnosis of tumors in the anterior arch of the atlas. Relevant measurements were obtained by assessing CT scans of 50 volunteers to assist operators to determine the effective and safe range for transnasal atlas biopsy.
Inhibition of Growth and Metastasis of Tumor in Nude Mice after Intraperitoneal Injection of Bevacizumab
Authors: Zhao Ze‐xue , Li Xiang , Liu Wei‐dong , Liu Xiao‐zhou , Wu Su‐jia , Hu Xiao‐hui 
Published: July 2016

ObjectiveTo explore the inhibitory effect of bevacizumab, a vascular endothelial growth factor antibody, on angiogenesis in human osteosarcoma of nude mice.MethodsTwenty‐one nude mice were inoculated with red fluorescent protein (RFP)‐labeled human osteosarcoma cell line 143B‐RFP, that is, clones that expressed RFP in the cytoplasm, and randomly assigned to one of three groups: G1 (Control group, injected with saline solution); G2 (intraperitoneal bevacizumab 2 mg/kg twice per week) and G3 (intraperitoneal bevacizumab 5 mg/kg, twice per week). The tumor‐bearing mice were examined in a fluorescence light box that was illuminated periodically. The primary tumors were measured by fluorescence imaging weekly and their volumes calculated.ResultsThe mean tumor volumes were significantly smaller in the G3 (186.4 ± 100.8 mm3) than the control group (587.0 ± 406.8 mm3) (P < 0.05) on Day 31, and again significantly smaller in the G3 (677.3 ± 461.9 mm3) than the control group (3162.6 ± 1529.2 mm3) on Day 38 (P < 0.01). The average tumor volume in the G2 group was 493.5 ± 425.4 mm3 on Day 31 and 1870.1 ± 1524.8 mm3 on Day 38. The effect on tumor volume was greater in the G3 than the G2 group. Three mice in the G2 group, four in the G3 group and four in the control group developed lung metastases that were confirmed by pathological examination; these differences were not statistically significant (P < 0.05).ConclusionsBevacizumab exhibits strong antiangiogenesis activity in experimental osteosarcoma in a nude mouse model but does not influence the incidence of lung metastasis. Our findings may have considerable potential for the treatment of osteosarcoma.
Malignant Pelvic Tumors Involving the Sacrum: Surgical Approaches and Procedures Based on a New Classification
Authors: Zhang Yi‐dan , Guo Wei , Yang Rong‐li , Tang Xiao‐dong , Yan Tai‐qiang , Ji Tao 
Published: July 2016

ObjectiveTo introduce a new classification of Enneking type IV pelvic tumors involving the sacrum and a corresponding system of standardized surgical approaches and procedures for resection of such tumors, and to investigate the feasibility and therapeutic effect of the new system.MethodsData on 59 patients treated between February 2003 and February 2013 by standardized surgical approaches and procedures were retrospectively reviewed. The study subjects comprised 28 male and 31 female patients with a mean age at diagnosis of 36 years (range, 2–72 years). There are four subtypes in the new classification: (i) subtype IVa, neoplasms invading the ipsilateral sacral wing; (ii) subtype IVb, neoplasms invading the ipsilateral sacral foramina; (iii) subtype IVc, neoplasms invading the contralateral sacral foramina; and (iv) subtype IVd, neoplasms invading the whole of the sacrum. Standardized surgical approaches and procedures were devised for en‐bloc resection for each subtype with adequate margins.ResultsAdequate margins were achieved in 43/59 patients (72.9%). The mean operation time was 5.0 h and the mean intraoperative blood loss 2157 mL. At the final follow‐up, 27/53 patients (50.9%) who had been followed up were alive and in complete remission. The mean Musculoskeletal Tumor Society 93 score was 17.4 (58%) of a possible 30 points. The mean functional score for patients who had undergone a pelvic zone II resection was 15.2, compared with 19.0 for those with an intact pelvic zone II.ConclusionsThe proposed standardized protocols should help orthopaedic surgeons to achieve adequate margins, manage risk, achieve better oncologic and functional outcomes, and minimize perioperative complications when treating massive pelvic tumors involving the sacrum.
Functional Results and Emotional Acceptance after Scapulectomy for Malignant Shoulder Tumors
Authors: Xu Song‐feng , Yu Xiu‐chun , Xu Ming , Hu Yong‐cheng , Liu Xiao‐ping 
Published: July 2016

ObjectivesTo demonstrate the functional results and emotional acceptance after scapulectomy for various malignant shoulder tumors.MethodsEight patients with malignant shoulder tumors who had undergone scapulectomy between April 2004 and March 2014 were retrospectively reviewed. They comprised seven men and one woman their mean age was 54 years (range, 24–69 years). All patients were diagnosed by pathological examination of biopsy specimens. The tumors were metastatic in four cases, having originated from a primary carcinoma of the liver in one patient, the lung in one patient and the kidney in two patients. The other four patients had primary malignant tumors in their scapulae, specifically, two scapular malignant fibrous histiocytomas, one scapular Ewing sarcoma and one soft tissue synovial sarcoma. The four patients with metastases were staged as III, and other four were staged as IIB. Six patients underwent total and two subtotal scapulectomy. The remaining soft tissues were sutured together directly in seven of the patients. The remaining patient, who had soft tissue synovial sarcoma, required transfer of a pedicle latissimus dorsi muscle flap. The functional results and emotional acceptance were evaluated by clinician using the Musculoskeletal Tumor Society (MSTS) scoring system.ResultsThe average duration of follow‐up was 22.8 months. Four patients were continuously disease‐free, three patients developed metastases and died of disease within 12 months of surgery and one patient with a scapular metastasis from the kidney survived with pulmonary nodules. No major complications, including infection or dislocation, occurred during or after surgery. The mean MSTS score was 16.3 (54%), which is similar to that previously reported in other studies of scapulectomy. There were no local tumor recurrences and only one patient developed pulmonary metastases. These outcomes are similar to those reported for scapular prostheses and there were fewer complications than in patients treated with allografts. The mean emotional acceptance score was 3.6 (72.5%).ConclusionsPerforming scapulectomies on patients with malignant shoulder tumors without prostheses or allograft reconstruction achieves good functional results and emotional acceptance with a low rate of complications.