bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information theoretical measures from cumulative and survival densities in quantum systems
Authors: Laguna Humberto G. , Sagar Robin P. 
Published: April 2017

AbstractEntropic uncertainty and statistical correlation measures, based on survival and cumulative densities, are explored in some representative quantum systems. We illustrate how the cumulative residual entropy in the quantum well system recovers the correct classical behavior for larger quantum numbers while the Shannon entropy does not. Two interacting and noninteracting oscillators are used to examine two‐particle entropies and their related correlation measures. The joint cumulative residual entropy does distinguish between symmetric and antisymmetric wave functions in interacting systems as the interaction is turned on. The joint Shannon entropy does not distinguish between the symmetries even in the presence of interaction. Conversely, the joint Shannon entropy and joint cumulative residual entropy are both unable to distinguish between the symmetries for certain states of the noninteracting oscillators. As measures of statistical correlation, the mutual information and the cross cumulative residual entropy yield similar behaviors as a function of the strength of the interparticle interaction.
Resonance Raman and UV‐Visible Microscopy Reveals that Conditioning Red Blood Cells with Repeated Doses of Sodium Dithionite Increases Haemoglobin Oxygen Uptake
Authors: Perez–Guaita David , de Veij Marleen , Marzec Katarzyna M. , Almohammedi Abdullah R. D. , McNaughton Don , Hudson Andrew J. , Wood Bayden R. 
Published: April 2017

AbstractHere we report that successive additions of fresh dithionite to a suspension of red blood cells (RBCs) increase the capacity of the cells to uptake oxygen. This effect was not observed when the RBCs were similarly preconditioned using gaseous N2 to induce short episodes of hypoxia. The effect of successive sodium dithionite and N2 gas additions on a population of functional erythrocytes was monitored using Raman confocal microscopy, with 514 nm excitation, and UV–visible microscopy. The results indicate that successive additions of sodium dithionite in a suspension of red blood cells leads to an increase in both the rate and the capacity of the RBCs to uptake oxygen. The sodium dithionite did not cause haemoglobin from lysed RBCs to uptake more oxygen after successive additions and hence this effect was only observed in functional intact RBCs. Experiments performed with polarised Raman spectroscopy suggest that sodium dithionite increases the disorder of Hb in the RBC facilitating oxygen diffusion.
Genomics‐Driven Discovery of the Gliovirin Biosynthesis Gene Cluster in the Plant Beneficial Fungus Trichoderma Virens
Authors: Sherkhane Pramod D. , Bansal Ravindra , Banerjee Kaushik , Chatterjee Suchandra , Oulkar Dasharath , Jain Prachi , Rosenfelder Lea , Elgavish Sharona , Horwitz Benjamin A. , Mukherjee Prasun K. 
Published: April 2017

AbstractGliovirin is a strong anti‐oomycete and a candidate anticancer compound. It is produced by “P” strains of the plant disease biocontrol fungus Trichoderma virens and is involved in biological control of certain plant pathogens. Even though the compound is known for more than three decades, neither the genes involved nor the biosynthetic pathway are known. We have sequenced the whole genome of a gliovirin producing strain of T. virens and discovered a novel gene cluster comprising of 22 genes. Disruption of the non‐ribosomal peptide synthetase eliminated biosynthesis of gliovirin. The gene cluster is very similar to a hitherto un‐described gene cluster of Aspergillus udagawae, a human pathogen. Our findings open‐up the possibility of strain improvement of T. virens for improved biocontrol of plant diseases through enhanced production of gliovirin. Research also can now be initiated on the role of this gene cluster in pathogenicity of the human pathogen A. udagawae.
Bismuth Nitrate Catalyzed One‐Pot Multicomponent Synthesis of a Novel Series of Diversely Substituted 1,8‐Dioxodecahydroacridines at Room Temperature#
Authors: Brahmachari Goutam , Begam Sanchari , Nurjamal Khondekar 
Published: April 2017

AbstractA simple, straightforward, and convenient one‐pot synthesis of a new series of diversely substituted 1,8‐dioxodecahydroacridines (5a–q and 5′a–g), particularly bearing varying amino acids as part of the building block, has been developed based on a low‐cost and environmentally benign Bi(NO3)3.5H2O catalyst via pseudo‐four component reactions of 1,3‐cyclohexanediones (1/4), various primary amines (2) and aldehydes (3) in ethanol at ambient temperature (25‐30 oC). High atom‐economy, good to excellent yields, eco‐friendliness, and mild reaction conditions are some of the important features of this protocol.
A Simple Chemical Route toward High Surface Area CeO2 Nanoparticles Displaying Remarkable Radical Scavenging Activity
Authors: Saikia Himadri , Hazarika Kumar Kashyap , Chutia Bhugendra , Choudhury Biswajit , Bharali Pankaj 
Published: April 2017

AbstractThis work reports a simple chemical route to synthesize high surface area ceria (CeO2) nanoparticles which exhibit remarkable radical scavenging activity. Synthesized CeO2 nanoparticles are characterized by thermogravimetric analysis (TGA), X‐ray diffraction (XRD), Fourier‐transform infrared spectroscopy (FTIR) and Raman spectroscopy, scanning electron microscopy (SEM), energy‐dispersive X‐ray analysis (EDX), transmission electron microscopy (TEM), and Brunauer‐Emmett‐Teller surface area (BET surface area) analyses. The characterization results reveal the formation of cubic phase of CeO2 with particles sizes of 10 nm and a remarkably high specific surface area of 236.8 m2/g. The nanoparticles are explored for 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) and hydroxyl radical scavenging activity that is to assess the antioxidant property of nanoceria by in‐vitro spectrophotometric approach.
Fabrication of a Graphene@TiO2@Porphyrin Hybrid Material and Its Photocatalytic Properties under Simulated Sunlight Irradiation
Authors: La Duong Duc , Bhosale Sidhanath V. , Jones Lathe A. , Revaprasadu Neerish , Bhosale Sheshanath V. 
Published: April 2017

AbstractThe fabrication of a nanostructured graphene@TiO2@porphyrin composite was achieved via surfactant‐assisted self‐assembly. The obtained nanostructures were fully characterized by UV‐vis, fluorescence emission spectroscopy, SEM, XRD and FTIR techniques. The graphene@TiO2@porphyrin composite reveals good incorporation of TiO2 particles with a diameter of 15–30 nm, and aggregated porphyrin nanorods with 50–60 nm width and several hundreds of nanometers in length on the graphene surface. The applications of three components (graphene@TiO2@porphyrin) based nanostructure in photocatalytic pollutant degradation Rhodamine B is reported, where TiO2 and porphyrin aggregates are shown to be activated for UV and visible light respectively, resulting in a high performing composite. The possible photocatalytic mechanism of RhB degradation by graphene@TiO2@porphyrins composite is discussed.
An estradiol‐inducible promoter enables fast, graduated control of gene expression in fission yeast
Authors: Ohira Makoto J. , Hendrickson David G. , Scott McIsaac R. , Rhind Nicholas 
Published: April 2017

AbstractThe fission yeast Schizosaccharomyces pombe lacks a diverse toolkit of inducible promoters for experimental manipulation. Available inducible promoters suffer from slow induction kinetics, limited control of expression levels and/or a requirement for defined growth medium. In particular, no S. pombe inducible promoter systems exhibit a linear dose–response, which would allow expression to be tuned to specific levels. We have adapted a fast, orthogonal promoter system with a large dynamic range and a linear dose response, based on β‐estradiol‐regulated function of the human oestrogen receptor, for use in S. pombe. We show that this promoter system, termed Z3EV, turns on quickly, can reach a maximal induction of 20‐fold, and exhibits a linear dose response over its entire induction range, with few off‐target effects. We demonstrate the utility of this system by regulating the mitotic inhibitor Wee1 to create a strain in which cell size is regulated by β‐estradiol concentration. This promoter system will be of great utility for experimentally regulating gene expression in fission yeast. Copyright © 2017 John Wiley & Sons, Ltd.
Existential Perspectives on Supervision
Authors: Deurzen Emmy van , Young Sarah 
Published: April 2017

Supervision is an essential part of counselling and psychotherapy practice. It is increasingly recognised as a tool for ensuring high professional standards. In an era of regulation and tightening control, there is a growing professional need to take stock and reflect on what it means to work with human problems. It is vital that therapists address the moral and philosophical dimensions of their profession and ask themselves what it is to be human.
This rich and far-reaching book explores supervision from this timely philosophical perspective. Designed both for trainees and more seasoned professionals, whatever their theoretical orientation, it makes a clear case for seeing existential perspectives on supervision as complementary to, rather than as a substitute for, other forms of supervision.
Local distribution of native and invasive earthworms and effects on a native salamander
Authors: Ransom Tami S. 
Published: April 2017

AbstractNorth America is home to both native and invasive earthworms acting as ecosystem engineers as they build burrows that can serve as habitat for other species or otherwise alter soil structure, affecting nutrient cycling and other ecosystem processes. Here I determine where and what earthworm species commonly occur in my study area, and compare effects of native and invasive earthworms on the common woodland salamander, Plethodon cinereus, in field surveys and laboratory experiments. The native earthworm Eisenoides carolinensis was the most common earthworm, followed by two invasive species Dendrobaena octaedra and Octolasion tyrtaeum. The presence of O. tyrtaeum was associated with a narrower O‐horizon (i.e., organic layer in the soil). Using structural equation modeling to explore direct and indirect pathways of these three most common earthworm species on salamanders, I found O. tyrtaeum occurrence was negatively correlated with nighttime salamander counts, a proxy for total salamander numbers, mediated by negative effects on O‐horizon depth and microinvertebrate numbers. In the laboratory, O. tyrtaeum and D. octaedra consumed more leaf litter per gram of earthworm per day than the native E. carolinensis. However, salamanders consumed earthworms and used burrows of all native and invasive species of earthworms similarly. The potential for negative indirect effects of the invasive earthworm O. tyrtaeum on P. cinereus was demonstrated both in the field and laboratory, highlighting that seemingly small differences between native and invasive ecosystem engineers have the potential to significantly alter the effects of these closely related native and invasive organisms.
Molecular therapy of primary hyperoxaluria
Authors: Martin‐Higueras Cristina , Torres Armando , Salido Eduardo 
Published: April 2017

AbstractDuring the last few decades, the molecular understanding of the mechanisms involved in primary hyperoxalurias (PHs) has set the stage for novel therapeutic approaches. The availability of PH mouse models has facilitated preclinical studies testing innovative treatments. PHs are autosomal recessive diseases where the enzymatic deficit plays a central pathogenic role. Thus, molecular therapies aimed at restoring such deficit or limiting the consequences of the metabolic derangement could be envisioned, keeping in mind the specific challenges posed by the cell‐autonomous nature of the deficiency. Various molecular approaches like enzyme replacement, substrate reduction, pharmacologic chaperones, and gene and cell therapies have been explored in cells and mouse models of disease. Some of these proof‐of‐concept studies have paved the way to current clinical trials on PH type 1, raising hopes that much needed treatments will become available for this severe inborn error of metabolism.
The Choice Theory of Contracts
Authors: Dagan Hanoch , Heller Michael 
Published: April 2017

This concise landmark in law and jurisprudence offers the first coherent, liberal account of contract law. The Choice Theory of Contracts answers the field&apos;s most pressing questions: what is the &apos;freedom&apos; in &apos;freedom of contract&apos;? What core values animate contract law and how do those values interrelate? How must the state act when it shapes contract law? Hanoch Dagan and Michael Heller - two of the world&apos;s leading private law theorists - show exactly why and how freedom matters to contract law. They start with the most appealing tenets of modern liberalism and end with their implications for contract law. This readable, engaging book gives contract scholars, teachers, and students a powerful normative vocabulary for understanding canonical cases, refining key doctrines, and solving long-standing puzzles in the law.
Thermonuclear Burst Observations for Model Comparisons: A Reference Sample
Authors: Galloway Duncan K. , Goodwin Adelle J. , Keek Laurens 
Published: April 2017

AbstractWe present observations of thermonuclear (type-I) X-ray bursts, selected for comparison with numerical models. We provide examples of four distinct cases of ignition: He-ignition in mixed H/He fuel (case 1); He-ignition in pure He fuel, following exhaustion of accreted H by steady burning (case 2); ignition in (almost) pure He accumulated from an evolved donor in an ultracompact system; and a superburst, thought to arise from ignition of carbon fuel produced as a by-product of H/He bursts. For regular bursts, we measured the recurrence time and calculated averaged burst profiles from RXTE observations. We also estimated the recurrence time for pairs of bursts, including those observed during a transient outburst, modelled using a numerical ignition code. For each example we list the burst properties including recurrence time, fluence, peak flux, the persistent flux level (and inferred accretion rate), and the ratio of persistent flux to fluence. In the accompanying material, we provide a bolometric lightcurve for each burst, determined from time-resolved spectral analysis. Along with the inferred or adopted parameters for each burst system, including distance, surface gravity, and redshift, these data are suggested as suitable test cases for ignition models.
A place to stand: Proverbs 8 and the construction of ecclesial space
Authors: Collett Donald 
Published: April 2017

AbstractRecent debate over the question whether’amônin Proverbs 8:30 should be rendered in a passive or active sense is helpful for illuminating the nature of the interaction between theology and exegesis in biblical interpretation. This essay offers an assessment of this debate with a view towards clarifying its christological significance, arguing that the semantics and syntax of Proverbs 8:30, as well as the theological frame of reference established by verses 22–31, exert an ‘ontological pressure’ upon our understanding of divine identity in Proverbs 8. These considerations offer an alternative avenue of approach to the poem that honours the Old Testament's commitment to monotheism, while also allowing the Old Testament's own presentation to shape our understanding of the character of theLord’s oneness.
Augustine's immanent critique of Stoicism
Authors: Boersma Gerald P. 
Published: April 2017

AbstractThe broad contours of Augustine's critique of Stoic virtue theory in De civitate dei 19.4 finds a fascinating analogue in Theodor Adorno's theory of immanent critique: Augustine ‘enters’ into Stoic virtue theory and criticises it from its own postulates, illustrating the striking implausibility of Stoic orthodoxy when lived out in concreto and the absurd, but logical, conclusions to which one is necessarily carried by Stoic ethics. Through this deconstruction, Augustine clears a space to propose his own virtue ethic. Augustine maintains that a Stoic virtue ethic fails to deliver on its promised eudaimonistic ends because it lacks a robust eschatological vision. For Augustine, the Christian faith offers a more viable virtue ethic.
The importance of the doctrine of justification in the theology of Thomas F. Torrance and of Karl Barth
Authors: Molnar Paul D. 
Published: April 2017

AbstractThis discussion of the interaction between Thomas F. Torrance and Karl Barth first highlights how and why the doctrine of justification binds them together theologically, since each theologian applies this doctrine relentlessly to all aspects of theology. The article then explores how their views of religion illustrate their thinking. Finally, it considers two areas of disagreement between Barth and Torrance regarding the issue of subordination within the doctrine of the Trinity and the possibility of natural theology.
Colonial Mobility and Ambiguity: The Life of Filmmaker Hinatsu/Huyung
Authors: Barker Thomas 
Published: April 2017

AbstractColonial subjects caught up supporting colonialism have often been seen as either engaging in an encounter of ambivalence or seen as traitors in post-independence nationalist historiography. Rather than following this established binary of possible subject positions, this article considers the unique biography of a filmmaker known in Indonesia as Dr Huyung. Prior work on Dr Huyung has either considered the pre and post 1945 stages of his life in isolation thus making incomplete assessments of his life and contributions. By bringing these two periods into conversation, a complete biography enables a more complex idea of colonial subjectivity to emerge. Huyung's life provides an alternative history of colonialism and an entry point in which to interrogate the limits and opportunities available in Asia of the 1930s to 1950s.This article traces the life of Dr Huyung from his birth in Korea as Hoe Yong, his life under Japanese occupation when he became Hinatsu Eitaro and moved to Japan to study film, to Indonesia as a Japanese propaganda officer, and finally to a new identity as Dr Huyung in independent Indonesia. As a trans-national subject operating across multiple subject positions – including colonial subject, colonial agent, and supporter of independence – this article challenges how subjectivity is thought about under colonialism and the historiography of national cinema in Indonesia, and contributes to understand his role in helping define and shape arts and culture in post-colonial Indonesia.
Metformin suppresses triple-negative breast cancer stem cells by targeting KLF5 for degradation
Authors: Shi Peiguo , Liu Wenjing , Tala  , Wang Haixia , Li Fubing , Zhang Hailin , Wu Yingying , Kong Yanjie , Zhou Zhongmei , Wang Chunyan , Chen Wenlin , Liu Rong , Chen Ceshi 
Published: April 2017

AbstractOut of the breast cancer subtypes, triple-negative breast cancer (TNBC) has the poorest prognosis without effective targeted therapies. Metformin, a first-line drug for type 2 diabetes mellitus, was demonstrated to target breast cancer stem cells selectively. However, the efficiency and the mechanism of action of metformin in TNBC are unclear. In this study, we demonstrated that metformin decreased the percentage of TNBC stem cells partially through the downregulation of the expression of the stem cell transcription factor Krüppel-like factor 5 (KLF5) and its downstream target genes, such as Nanog and FGF-BP1, in TNBC cell lines. Metformin induced glycogen synthase kinase-3β (GSK3β)-mediated KLF5 protein phosphorylation and degradation through the inhibition of protein kinase A (PKA) activity in TNBC cells. Consistently, PKA activators increased the expression levels of KLF5. We observed a positive correlation between p-CREB, p-GSK3β, KLF5 and FGF-BP1 protein levels in human TNBC samples. These findings suggest that metformin suppresses TNBC stem cells partially through the PKA-GSK3β-KLF5 signaling pathway.
Enhanced superconductivity accompanying a Lifshitz transition in electron-doped FeSe monolayer
Authors: Shi X. , Han Z-Q , Peng X-L , Richard P. , Qian T. , Wu X-X , Qiu M-W , Wang S. C. , Hu J. P. , Sun Y-J , Ding H. 
Published: April 2017

AbstractThe origin of enhanced superconductivity over 50 K in the recently discovered FeSe monolayer films grown on SrTiO3 (STO), as compared to 8 K in bulk FeSe, is intensely debated. As with the ferrochalcogenides AxFe2−ySe2 and potassium-doped FeSe, which also have a relatively high-superconducting critical temperature (Tc), the Fermi surface (FS) of the FeSe/STO monolayer films is free of hole-like FS, suggesting that a Lifshitz transition by which these hole FSs vanish may help increasing Tc. However, the fundamental reasons explaining this increase of Tc remain unclear. Here we report a 15 K jump of Tc accompanying a second Lifshitz transition characterized by the emergence of an electron pocket at the Brillouin zone centre, which is triggered by high-electron doping following in situ deposition of potassium on FeSe/STO monolayer films. Our results suggest that the pairing interactions are orbital dependent in generating enhanced superconductivity in FeSe.
Localization of Laplacian eigenvectors on random networks
Authors: Hata Shigefumi , Nakao Hiroya 
Published: April 2017

AbstractIn large random networks, each eigenvector of the Laplacian matrix tends to localize on a subset of network nodes having similar numbers of edges, namely, the components of each Laplacian eigenvector take relatively large values only on a particular subset of nodes whose degrees are close. Although this localization property has significant consequences for dynamical processes on random networks, a clear theoretical explanation has not yet been established. Here we analyze the origin of localization of Laplacian eigenvectors on random networks by using a perturbation theory. We clarify how heterogeneity in the node degrees leads to the eigenvector localization and that there exists a clear degree-eigenvalue correspondence, that is, the characteristic degrees of the localized nodes essentially determine the eigenvalues. We show that this theory can account for the localization properties of Laplacian eigenvectors on several classes of random networks, and argue that this localization should occur generally in networks with degree heterogeneity.
Effects of elevated CO2 on the fitness and potential population damage of Helicoverpa armigera based on two-sex life table
Authors: Liu Jinping , Huang Wenkun , Chi Hsin , Wang Chonghui , Hua Hongxia , Wu Gang 
Published: April 2017

AbstractWe evaluated the direct effects of three different atmospheric CO2 concentrations (380 ppm, 550 ppm and 750 ppm) on the population parameters of the cotton bollworm, Helicoverpa armigera fed an artificial diet. The life history and fitness of H. armigera were analyzed using an age-stage, two-sex life table. Our results showed significantly longer larval durations and lower female pupal weight under elevated CO2 than under ambient CO2. Additionally, the fecundity of H. armigera was lower under elevated CO2 than under ambient CO2. H. armigera reared under elevated CO2 conditions showed lower intrinsic and finite rates of increase but higher net consumption and finite consumption rates than H. armigera reared under ambient CO2 conditions. According to population projections, a much smaller total population size and reduced consumption capacities would be expected in an elevated CO2 atmosphere due to higher mortality and lower growth rate compared with ambient CO2 levels. These results indicate that the fitness of and potential damage caused by H. armigera would be affected by increased CO2 relative to ambient CO2 concentrations. Additional studies on the long-term direct and indirect effects of elevated CO2 levels on H. armigera are still needed.