bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling habitat suitability for the Critically Endangered Manumea or Tooth-billed PigeonDidunculus strigirostrisusing past and present baselines
Authors: Gough William B. , Hudson Michael A. , Young H. Glyn , Wood Joe , Whitehead Hester , Turvey Samuel T. 
Published: September 2024

SummaryEvidence-based conservation can be hindered by limited field data, but historical archives have the potential to provide unique insights into conservation-relevant parameters, such as identification of suitable habitat for threatened species. The Manumea or Tooth-billed PigeonDidunculus strigirostrishas declined on Samoa and only a tiny remnant population still persists, and a key first step for conservation is to locate surviving birds. Numerous Manumea records are available from the nineteenth century onwards, and we used historical and modern records to generate a series of species distribution models to predict the distribution of suitable habitat across Samoa to guide new field searches. Manumea distribution is closely associated with forest cover or its proxies. Preferred Manumea food plants are suggested to be low-elevation trees, but elevation provides relatively low percentage contribution in most models, thus not excluding the possibility that Manumea might occur at high elevations. There is also little evidence for elevational change in records over the past century. Models based on visual versus acoustic records exhibit differences in predicted habitat suitability, suggesting that some purported acoustic records might not actually represent Manumea calls. Field searches should target areas representing high habitat suitability across all models, notably the forested central axis of Upolu.
GPS tracking reveals the timing of collisions with powerlines and fences of three threatened steppe bird species
Authors: Marques Ana Teresa , Pacheco Carlos , Mougeot François , Silva João Paulo 
Published: September 2024

Summary
Collision with powerlines is a major cause of mortality for many bird species, including bustards and sandgrouse. In this work, we used GPS tracking data to identify the hour of collision of three threatened steppe birds, i.e. Little Bustard Tetrax tetrax, Black-bellied Sandgrouse Pterocles orientalis, and Pin-tailed Sandgrouse Pterocles alchata. Out of a data set of 160 GPS-tracked individuals collected over a 13-year period, we detected eight collision events with powerlines or fences. Of these, we were able to determine the timing of 87.5% of the collision events with a resolution accurate to within two hours. Our results reveal that collisions occurred throughout the year and at different hours of the day, presenting a challenge for implementing effective mitigation strategies. The use of dynamic and reflective or luminescent devices may therefore be appropriate to prevent collision of steppe birds with powerlines during the day and night. Overall, this study adds evidence to the utility of using tracking data to better understand anthropogenic mortality in birds.
Internalizing and somatic symptoms influence the discrepancy between subjective and objective cognitive difficulties in adults with ADHD who have valid and invalid test scores
Authors: Finley John-Christopher A. , Robinson Anthony D. , VanLandingham Hannah B. , Ulrich Devin M. , Phillips Matthew S. , Soble Jason R. 
Published: September 2024

AbstractObjectives:This study investigated the relationship between various intrapersonal factors and the discrepancy between subjective and objective cognitive difficulties in adults with attention-deficit hyperactivity disorder (ADHD). The first aim was to examine these associations in patients with valid cognitive symptom reporting. The next aim was to investigate the same associations in patients with invalid scores on tests of cognitive symptom overreporting.Method:The sample comprised 154 adults who underwent a neuropsychological evaluation for ADHD. Patients were divided into groups based on whether they had valid cognitive symptom reporting and valid test performance (n = 117) or invalid cognitive symptom overreporting but valid test performance (n = 37). Scores from multiple symptom and performance validity tests were used to group patients. Using patients’ scores from a cognitive concerns self-report measure and composite index of objective performance tests, we created a subjective-objective discrepancy index to quantify the extent of cognitive concerns that exceeded difficulties on objective testing. Various measures were used to assess intrapersonal factors thought to influence the subjective-objective cognitive discrepancy, including demographics, estimated premorbid intellectual ability, internalizing symptoms, somatic symptoms, and perceived social support.Results:Patients reported greater cognitive difficulties on subjective measures than observed on objective testing. The discrepancy between subjective and objective scores was most strongly associated with internalizing and somatic symptoms. These associations were observed in both validity groups.Conclusions:Subjective cognitive concerns may be more indicative of the extent of internalizing and somatic symptoms than actual cognitive impairment in adults with ADHD, regardless if they have valid scores on cognitive symptom overreporting tests.
Nonseparability of credit card services within Divisia monetary aggregates
Authors: Barnett William A. , Park Hyun 
Published: September 2024

Abstract
We use the New Keynesian Dynamic Stochastic General Equilibrium (DSGE) framework and Vector Autoregressive (VAR) to investigate the usefulness and relevancy of monetary services, augmented to include credit card transaction services. We use the new credit-card-augmented Divisia monetary aggregates in the models to further the existing research on their usefulness and relevancy. In this research, we compare three different monetary aggregates within the New Keynesian framework: (1) the aggregation-theoretic “true” monetary aggregate, (2) the credit-card-augmented Divisia monetary aggregate, and (3) the simple sum monetary aggregate.
We acquire the following primary results. (1) The credit-card-augmented Divisia monetary aggregate tracks the theoretical (true) monetary aggregate, while simple sum does not. Although this result would be expected from the theory in classical economic models, the result is not an immediate implication of the theory in New Keynesian models and therefore needs empirical confirmation. (2) Under the recursive VAR framework, the credit-card-augmented Divisia monetary aggregate serves as a preferable monetary policy indicator compared to the traditional federal funds rate. (3) On theoretical grounds, we find that the separability condition for existence of a monetary aggregator function could fail, if credit card deferred payment services were excluded from the monetary services block, unless all markets are perfect.
Observation of significant photosynthesis in garden cress and cyanobacteria under simulated illumination from a K dwarf star
Authors: Vilović Iva , Schulze-Makuch Dirk , Heller René 
Published: September 2024

Abstract
Stars with about 45 to 80% the mass of the Sun, so-called K dwarf stars, have previously been proposed as optimal host stars in the search for habitable extrasolar worlds. These stars are abundant, have stable luminosities over billions of years longer than Sun-like stars, and offer favourable space environmental conditions. So far, the theoretical and experimental focus on exoplanet habitability has been on even less massive, though potentially less hospitable red dwarf stars. Here we present the first experimental data on the responses of photosynthetic organisms to a simulated K dwarf spectrum. We find that garden cress Lepidium sativum under K-dwarf radiation exhibits comparable growth and photosynthetic efficiency as under Solar illumination on Earth. The cyanobacterium Chroococcidiopsis sp. CCMEE 029 exhibits significantly higher photosynthetic efficiency and culture growth under K dwarf radiation compared to Solar conditions. Our findings of the affirmative responses of these two photosynthetic organisms to K dwarf radiation suggest that exoplanets in the habitable zones around such stars deserve high priority in the search for extrasolar life.
Effectiveness of partial restriction of access to means in jumping suicide: lessons from four bridges in three countries
Authors: Shin Sangsoo , Pirkis Jane , Clapperton Angela , Spittal Matthew , Too Lay San 
Published: September 2024

Abstract

Aims
Restricting access to means by installing physical barriers has been shown to be the most effective intervention in preventing jumping suicides on bridges. However, little is known about the effectiveness of partial restriction with interventions that still allow jumping from the bridge.

Methods
This study used a quasi-experimental design. Public sites that met our inclusion criteria were identified using Google search and data on jumping suicides on Bridge A (South Korea), Bridges B and C (the United States) and Bridge D (Canada) were obtained from the relevant datasets. Incidence rate ratios (IRRs) were estimated using Poisson regressions comparing suicide numbers before and after the installation of physical structures at each site.

Results
Fences with sensor wires and spinning handrails installed above existing railings on the Bridge A, and fences at each side of the entrances and the midpoint of main suspension cables on the Bridge D were associated with significant reductions in suicides (IRR 0.37, 95% Confidence Interval (CI) 0.26 − 0.54; 0.26, 95% CI 0.09 − 0.76). Installation of bird spike on the parapet on the Bridge B, and fences at the front of seating alcoves on the Bridge C were not associated with changes in suicides (1.21, 95% CI 0.88 − 1.68; 1.49, 95% CI 0.56 − 3.98).

Conclusions
Partial means restriction (such as fences with sensor wires and spinning bars at the top, and partial fencing at selected points) on bridges appears to be helpful in preventing suicide. Although these interventions are unlikely to be as effective as interventions that fully secure the bridge and completely prevent jumping, they might best be thought of as temporary solutions before more complete or permanent structures are implemented.
Effort in Hindustani Dhrupad Singing: Using Interviews to Develop Effort Inference Models of Acoustic and Movement Features
Authors: PASCHALIDOU STELLA 
Published: September 2024

AbstractThis article sets out the results of research into effort in Dhrupad, a genre of Hindustani music. I examine gestural interactions with imaginary objects that vocalists outline when engaging with melodies. The study takes an embodied cognition stance and applies thematic analysis and inductive coding to original interviews with Dhrupad musicians in India, the UK, and the Netherlands. My findings demonstrate that from the singers’ cognitive perspectives, their hand movements are deeply connected to their voices. I also offer insights on the relationships between bodily movement, sound, and imagery that are used to inform the development of effort inference models.
Neurological outcomes and associated perinatal factors in infants born between 22 and 25 weeks with active care
Authors: Ariyoshi Yu , Iriyama Takayuki , Seyama Takahiro , Sayama Seisuke , Yano Eriko , Suzuki Kensuke , Samejima Taiki , Ichinose Mari , Toshimitsu Masatake , Sone Kenbun , Ito Atsushi , Shitara Yoshihiko , Kumasawa Keiichi , Kashima Kohei , Kakiuchi Satsuki , Hirota Yasushi , Takahashi Naoto , Osuga Yutaka 
Published: September 2024

Abstract

Objectives
To elucidate the outcomes of periviable infants receiving active care (AC) and explore perinatal factors associated with neurodevelopmental outcomes.

Methods
This is a single-center retrospective study on infants born at 22–25 weeks of gestation, all of whom received AC. A developmental quotient (DQ) ≥ 85 at corrected 18 months was judged as normal.

Results
Fifty-seven infants were included in the study. The survival rates at discharge were 83%, 86%, 93%, and 93% at 22, 23, 24, and 25 gestational weeks, respectively. The overall percentage of normal DQ was 26/47 (55%). Acidemia in the arterial blood gas measured within 6 h after birth was identified as a factor significantly associated with subnormal DQ.

Conclusions
Not only high survival rates, but also favorable neurodevelopmental outcomes may be achieved by AC in periviable infants. Moreover, impaired neurodevelopmental outcomes may be associated with early postnatal acidemia following initial resuscitation.
Pyroptosis of oral keratinocyte contributes to energy metabolic reprogramming of T cells in oral lichen planus via OPA1-mediated mitochondrial fusion
Authors: Yang Zaiwu , Deng Miao , Ren Lin , Fan Zhaona , Yang Shiwen , Liu Suyang , Ren Xianyue , Gao Jinlong , Cheng Bin , Xia Juan 
Published: September 2024

AbstractOral lichen planus (OLP) is a chronic inflammatory disease that is associated with an increased risk of carcinogenesis. The typical pathological features of OLP include submucosal T-cell banding, infiltration, and liquefactive degeneration of basal epithelial cells. However, the histological appearance of basal cell death cannot be explained by apoptosis of keratinocytes alone. The aim of this study was to explore a novel mechanism of epithelial cell death, pyroptosis, and its role in the development of OLP. The immunohistochemical results initially revealed pyroptosis in the epithelial cells of OLP. There was significant upregulation of pyroptosis-related inflammatory cytokines, specifically IL-1β. The expression of IL-1β is closely related to the severity of the patient’s condition. In vitro, the culture supernatant from epithelial cells and exogenous IL-1β significantly promote the proliferation and activation of T cells. This effect can be inhibited by neutralizing antibody or receptor inhibitor of IL-1β. Stimulation with exogenous IL-1β enhances both glycolysis and oxidative phosphorylation in T cells, with a more pronounced increase in glycolysis. This is due to the regulation of NAD+ availability and mitochondrial dynamics by IL-1β. IL-1β specifically stimulates the expression of optic atrophy 1 (OPA1), particularly L-OPA1, which promotes mitochondrial fusion and increases NAD+ availability. This process upregulated glycolysis in T cells. The knockdown of OPA1 reverses these changes by reducing the proliferation and activation of T cells. In this study, IL-1β promoted OPA1 transcription by activating the NF-κB pathway. The expression of OPA1 is inhibited by the inhibitor of NF-κB pathway. These results suggest that OLP keratinocytes undergo pyroptosis, which then secrete inflammatory factors that activate the NF-κB signaling pathway of T cells. This pathway regulates OPA1-mediated mitochondrial fusion and energy metabolism reprogramming in T cells, contributing to the development of OLP. These findings provide new insights into the mechanisms and therapeutic strategies for OLP.
Analysing the pedigree to identify undesirable losses of genetic diversity and to prioritize management decisions in captive breeding: a case study
Authors: Moreno Eulalia , Cervantes Isabel , Gutiérrez Juan Pablo , Fernández Iván , Goyache Félix 
Published: September 2024

AbstractWhen prevention of species extinction is the priority, captive breeding is a key component in conservation programmes, allowing the recording of pedigree information in studbooks. The genealogical information registered in Cuvier’s gazelle studbook between 1975 and 2023 was analysed to (a) assess if the implemented mating policy was successful in preserving the genetic background of the founders (1 male:3 females) in the present population, and b) improve future management and breeding decisions. Although the maternal contribution of one founder female was lost and the mean inbreeding of the total live population was high (0.305 ± 0.095), the breeding policy applied produced better results than expected from a population starting from four founders. It was successful in keeping the individual increase in inbreeding low (0.047 ± 0.021), and, notably, the inbreeding tended to decrease during the last three decades of the breeding programme, ensuring the viability of this highly inbred population. Historical dissemination of individuals among the zoos of Europe and North America caused population structuring and genetic differentiation of the live North American population. However, it did not risk the viability of the captive population. The average relatedness coefficients allowed the identification of individuals with underrepresented genotypes, which is relevant to plan future mating guidelines to keep the founders’ representation balanced in the next generations. This study highlights the importance of keeping long-term pedigree information to monitor changes in the genetic diversity of captive populations, which is crucial to implement optimal mating decisions and assuring their long-term viability within an ex situ conservation programme.
Sensing data and methodology from the Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) clinical trial
Authors: Stanslaski Scott , Summers Rebekah L. S. , Tonder Lisa , Tan Ye , Case Michelle , Raike Robert S. , Morelli Nathan , Herrington Todd M. , Beudel Martijn , Ostrem Jill L. , Little Simon , Almeida Leonardo , Ramirez-Zamora Adolfo , Fasano Alfonso , Hassell Travis , Mitchell Kyle T. , Moro Elena , Gostkowski Michal , Sarangmat Nagaraja , Bronte-Stewart Helen ,   On behalf of the ADAPT-PD Investigators
Published: September 2024

AbstractAdaptive deep brain stimulation (aDBS) is an emerging advancement in DBS technology; however, local field potential (LFP) signal rate detection sufficient for aDBS algorithms and the methods to set-up aDBS have yet to be defined. Here we summarize sensing data and aDBS programming steps associated with the ongoing Adaptive DBS Algorithm for Personalized Therapy in Parkinson’s Disease (ADAPT-PD) pivotal trial (NCT04547712). Sixty-eight patients were enrolled with either subthalamic nucleus or globus pallidus internus DBS leads connected to a Medtronic PerceptTM PC neurostimulator. During the enrollment and screening procedures, a LFP (8–30 Hz, ≥1.2 µVp) control signal was identified by clinicians in 84.8% of patients on medication (65% bilateral signal), and in 92% of patients off medication (78% bilateral signal). The ADAPT-PD trial sensing data indicate a high LFP signal presence in both on and off medication states of these patients, with bilateral signal in the majority, regardless of PD phenotype.
Understanding flux switching in metabolic networks through an analysis of synthetic lethals
Authors: Narasimha Sowmya Manojna , Malpani Tanisha , Mohite Omkar S. , Nath J. Saketha , Raman Karthik 
Published: September 2024

AbstractBiological systems are robust and redundant. The redundancy can manifest as alternative metabolic pathways. Synthetic double lethals are pairs of reactions that, when deleted simultaneously, abrogate cell growth. However, removing one reaction allows the rerouting of metabolites through alternative pathways. Little is known about these hidden linkages between pathways. Understanding them in the context of pathogens is useful for therapeutic innovations. We propose a constraint-based optimisation approach to identify inter-dependencies between metabolic pathways. It minimises rerouting between two reaction deletions, corresponding to a synthetic lethal pair, and outputs the set of reactions vital for metabolic rewiring, known as the synthetic lethal cluster. We depict the results for different pathogens and show that the reactions span across metabolic modules, illustrating the complexity of metabolism. Finally, we demonstrate how the two classes of synthetic lethals play a role in metabolic networks and influence the different properties of a synthetic lethal cluster.
Space radiation measurements during the Artemis I lunar mission
Authors: George Stuart P. , Gaza Ramona , Matthiä Daniel , Laramore Diego , Lehti Jussi , Campbell-Ricketts Thomas , Kroupa Martin , Stoffle Nicholas , Marsalek Karel , Przybyla Bartos , Abdelmelek Mena , Aeckerlein Joachim , Bahadori Amir A. , Barzilla Janet , Dieckmann Matthias , Ecord Michael , Egeland Ricky , Eronen Timo , Fry Dan , Jones Bailey H. , Hellweg Christine E. , Houri Jordan , Hirsh Robert , Hirvonen Mika , Hovland Scott , Hussein Hesham , Johnson A. Steve , Kasemann Moritz , Lee Kerry , Leitgab Martin , McLeod Catherine , Milstein Oren , Pinsky Lawrence , Quinn Phillip , Riihonen Esa , Rohde Markus , Rozhdestvenskyy Sergiy , Saari Jouni , Schram Aaron , Straube Ulrich , Turecek Daniel , Virtanen Pasi , Waterman Gideon , Wheeler Scott , Whitman Kathryn , Wirtz Michael , Vandewalle Madelyn , Zeitlin Cary , Semones Edward , Berger Thomas 
Published: September 2024

AbstractSpace radiation is a notable hazard for long-duration human spaceflight1. Associated risks include cancer, cataracts, degenerative diseases2 and tissue reactions from large, acute exposures3. Space radiation originates from diverse sources, including galactic cosmic rays4, trapped-particle (Van Allen) belts5 and solar-particle events6. Previous radiation data are from the International Space Station and the Space Shuttle in low-Earth orbit protected by heavy shielding and Earth’s magnetic field7,8 and lightly shielded interplanetary robotic probes such as Mars Science Laboratory and Lunar Reconnaissance Orbiter9,10. Limited data from the Apollo missions11–13 and ground measurements with substantial caveats are also available14. Here we report radiation measurements from the heavily shielded Orion spacecraft on the uncrewed Artemis I lunar mission. At differing shielding locations inside the vehicle, a fourfold difference in dose rates was observed during proton-belt passes that are similar to large, reference solar-particle events. Interplanetary cosmic-ray dose equivalent rates in Orion were as much as 60% lower than previous observations9. Furthermore, a change in orientation of the spacecraft during the proton-belt transit resulted in a reduction of radiation dose rates of around 50%. These measurements validate the Orion for future crewed exploration and inform future human spaceflight mission design.
One step from oxides to sustainable bulk alloys
Authors: Wei Shaolou , Ma Yan , Raabe Dierk 
Published: September 2024

AbstractMetallurgical production traditionally involves three steps: extracting metals from ores, mixing them into alloys by liquid processing and thermomechanical processing to achieve the desired microstructures1,2. This sequential approach, practised since the Bronze Age, reaches its limit today because of the urgent demand for a sustainable economy2–5: almost 10% of all greenhouse gas emissions are because of the use of fossil reductants and high-temperature metallurgical processing. Here we present a H2-based redox synthesis and compaction approach that reforms traditional alloy-making by merging metal extraction, alloying and thermomechanical processing into one single solid-state operation. We propose a thermodynamically informed guideline and a general kinetic conception to dissolve the classical boundaries between extractive and physical metallurgy, unlocking tremendous sustainable bulk alloy design opportunities. We exemplify this approach for the case of Fe–Ni invar bulk alloys6,7, one of the most appealing ferrous materials but the dirtiest to produce: invar shows uniquely low thermal expansion6,8,9, enabling key applications spanning from precision instruments to cryogenic components10–13. Yet, it is notoriously eco-unfriendly, with Ni causing more than 10 times higher CO2 emission than Fe per kilogram production2,14, qualifying this alloy class as a perfect demonstrator case. Our sustainable method turns oxides directly into green alloys in bulk forms, with application-worthy properties, all obtained at temperatures far below the bulk melting point, while maintaining a zero CO2 footprint.