bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Application of Harvest Aid Herbicides Adversely Impacts Lentil
Authors: Zhang Ti , Johnson Eric N. , Mueller Thomas C. , Willenborg Christian J. 
Published: December 2016

Core Ideas
Improper application timing of harvest aids may reduce lentil seed yield and quality, and leave unacceptable herbicide residues in seed.
Application of harvest aids before 30% seed moisture content reduced lentil seed yield and thousand seed weight.
These application timings resulted in lentil seed samples exceeding residue levels of 2 and 0.03 mg kg−1 for glyphosate and saflufenacil, respectively.
Applying harvest aid herbicides can dry down lentil (Lens culinaris Medik.) crops evenly and quickly, and can help control late‐emerging weeds. However, improper application timing may reduce yield and quality, and leave unacceptable herbicide residues in seed, which can cause commercial issues when marketing lentil. The objective of this research was to determine the response of lentil to various application timings of glyphosate, saflufenacil, and the combination of these two herbicides. A field experiment consisting of a randomized complete block design was run at Saskatoon and Scott, SK, Canada in 2012, 2013, and 2014 to address the objective. Application of harvest aid herbicides before 30% seed moisture content reduced seed yield and thousand seed weight up to 25 and 8%, respectively. Moreover, application timings before 30% seed moisture resulted in lentil seed samples exceeding residue levels of 2.0 and 0.03 mg kg−1 for glyphosate and saflufenacil, respectively. Adding saflufenacil to glyphosate did not reduce glyphosate residue in lentil seed compared to glyphosate applied alone. However, this tank mixture significantly reduced seed residues of saflufenacil and improved crop desiccation compared with either glyphosate or saflufenacil applied alone. Our data lead us to conclude that a tank mix of saflufenacil+glyphosate should be recommended for crop desiccation and pre‐harvest weed control in lentil over using either product alone. In addition, it is critical to ensure applications of glyphosate or saflufenacil are not made prior to 30% seed moisture in lentil crops.
Combining Restricted Grazing and Nitrification Inhibitors to Reduce Nitrogen Leaching on New Zealand Dairy Farms
Authors: Romera Alvaro J. , Cichota Rogerio , Beukes Pierre C. , Gregorini Pablo , Snow Val O. , Vogeler Iris 
Published: December 2016

Intensification of pastoral dairy systems often means more nitrogen (N) leaching. A number of mitigation strategies have been proposed to reduce or reverse this trend. The main strategies focus on reducing the urinary N load onto pastures or reducing the rate of nitrification once the urine has been deposited. Restricted grazing is an example of the former and the use of nitrification inhibitors an example of the latter. A relevant concern is the cost effectiveness of these strategies, independently and jointly. To address this concern, we employed a modeling approach to estimate N leaching with and without the use of these mitigation options from a typical grazing dairy farm in New Zealand. Three restricted grazing options were modeled with and without a nitrification inhibitor (dicyandiamide, DCD) and the results were compared with a baseline farm (no restricted grazing, no inhibitor). Applying DCD twice a year, closely following the cows after an autumn and winter grazing round, has the potential to reduce annualized and farm‐scale N leaching by ∼12%, whereas restricted grazing had leaching reductions ranging from 23 to 32%, depending on the timing of restricted grazing. Combining the two strategies resulted in leaching reductions of 31 to 40%. The abatement cost per kilogram of N leaching reduction was NZ$50 with DCD, NZ$32 to 37 for restricted grazing, and NZ$40 to 46 when the two were combined. For the range analyzed, all treatments indicated similar cost per percentage unit of mitigated N leaching, demonstrating that restricted grazing and nitrification inhibitors can be effective when used concurrently.Core Ideas
Nitrogen leaching from pastoral dairy farms should be reduced.
We modeled the effectiveness of nitrification inhibitors and restricted grazing.
Nitrification inhibitors reduced N leaching by 12% and restricted grazing by 23 to 32%.
Combining the two strategies reduced N leaching by 31 to 40%.
Restricted grazing and nitrification inhibitors can be effective in combination.
Percutaneous mitral valve repair: The MitraClip device
Authors: Suradi Hussam S , Kavinsky Clifford J , Hijazi Ziyad M 
Published: December 2016

Chronic mitral regurgitation (MR) is the most common cardiac valvular disease with more than 4 million people in the United States alone suffering from moderate or severe MR. Left untreated, chronic MR results in serious consequences. Surgical correction with mitral valve repair or replacement remains the mainstay of therapy for MR. Nevertheless, a large proportion of patients may not be offered treatment due to concerns over surgical risk. This unmet therapeutic need for a less invasive approach led to a marked explosion in the development of a variety of transcatheter approaches to treat mitral regurgitation in the past decade. The majority of these devices are based on principles learned from surgical mitral valve repair techniques. Inspired by the Alfieri surgical technique, the MitraClip edge-to-edge repair system is the most advanced technique with the highest safety and efficacy to date. In this review, we discuss the current status of the MitraClip repair system in the treatment of mitral regurgitation.
Intracoronary near-infrared spectroscopy: an overview of the technology, histologic validation, and clinical applications
Authors: O'Brien Andrew , LaCombe Andrew , Stickland Aubrey , Madder Ryan D 
Published: December 2016

Intracoronary near-infrared spectroscopy (NIRS) imaging, which is now clinically available in a combined NIRS and intravascular ultrasound catheter, is a novel catheter-based imaging modality capable of identifying lipid core plaque within the coronary arteries of living patients. The present manuscript provides an overview of intracoronary NIRS imaging with a focus on several concepts essential to individuals seeking to better understand this novel imaging modality. One of the major assets of NIRS is that it has been rigorously validated against the gold standard of histopathology and has been shown to accurately identify histologically-proven fibroatheroma. Clinical studies of NIRS have demonstrated its ability to accurately identify large lipid core plaques at culprit lesions across the spectrum of acute coronary syndromes. NIRS has also been shown to detect lesions at increased risk of causing peri-procedural myocardial infarction during PCI. With regards to predicting future risk, NIRS is seemingly capable of identifying vulnerable patients at increased risk of experiencing subsequent patient-level cardiovascular events. In addition to these clinical applications of NIRS, there are several large prospective observational studies underway to determine if NIRS imaging will be able to identify vulnerable plaques at increased risk of triggering site-specific future coronary events. These studies, once completed, are anticipated to provide valuable data regarding the ability of NIRS imaging to identify plaque vulnerability.
Alginate for cardiac regeneration: From seaweed to clinical trials
Authors: Liberski Albert , Latif Najma , Raynaud Christophe , Bollensdorff Christian , Yacoub Magdi 
Published: December 2016

Heart failure is a growing endemic in the aging Western population with a prevalence of over 20 million people worldwide. Existing heart failure therapies are unable to reverse heart failure and do not address its fundamental cause, the loss of cardiomyocytes. In order to induce myocardial regeneration for the myocardium and the heart valve, facilitate self-repair, improve tissue salvage, reduce or reverse the adverse-remodeling and ultimately achieve long-term functional stabilization and improvement in the heart function, novel strategies for therapeutic regeneration are being developed which are aiming to compensate for the insufficient and low intrinsic regenerative ability of the adult heart. Similarly, valve replacement with mechanical or biological substitutes meets numerous hurdles. New approaches using multicellular approaches and new material are extensively studied. Most of those strategies depend on biomaterials that help to achieve functional integrated vasculogenesis and myogenesis in the heart/tissue. Especially for failed heart valve function a number of therapeutic approaches are common from corrective intervention to complete replacement. However the complexity of the heart valve tissue and its high physical exposure has led to a variety of approaches, however therapeutic regeneration needs to be established. Beside other approaches alginate has been identified as one building block to achieve therapeutic regeneration. Alginate is a versatile and adaptable biomaterial that has found numerous biomedical applications which include wound healing, drug delivery and tissue engineering. Due to its biologically favorable properties including the ease of gelation and its biocompatibility, alginate- based hydrogels have been considered a particularly attractive material for the application in cardiac regeneration and valve replacement techniques. Here, we review current applications of alginate in cardiac regeneration as well as perspectives for the alginate-dependent, cardiac regeneration strategies.
Determinants of Restrictive Spirometric Pattern in a Sub-Saharan Urban Setting: A Cross-sectional Population-based Study
Authors: Pefura-Yone Eric Walter , Balkissou Adamou Dodo , Kengne Andre Pascal 
Published: December 2016

Background
Restrictive spirometric pattern is a risk factor for all-cause and cause-specific mortality.

Objective
We assessed the prevalence of restrictive pattern and investigated its determinants in a major sub-Saharan Africa city.

Methods
Participants were adults (≥ 19 years) who took part in a population-based survey in Yaounde (Cameroon) between December 2013 and April 2014. Restrictive pattern was based on a FVC below the lower limit of the normal (LLN) and a ratio forced expiratory volume in one second (FEV1)/FVC ≥ LLN (LLN-based restrictive pattern) or a FVC <80% and FEV1/FVC ≥ LLN (fixed cut-off based restrictive pattern). Determinants were investigated by logistic regressions.

Results
In all, 1003 participants [514 (51.2%) women] with a mean age of 33.7 years were included. The prevalence of restrictive pattern was 18.8% (95%CI: 16.6-21.2) based on LLN and 15.0% (13.0-17.2) based on fixed cut-off. LLN-based restrictive pattern was mild in 148 (78.3%) subjects, moderate in 35 (18.5%) and severe in 6 (3.2%). Determinants of LLN-based restrictive pattern were age ≥ 60 years [adjusted odds ratio 2.90 (95%CI 1.46-5.77), p=0.002), history of pulmonary tuberculosis [3.81(1.42-10.20), p=0.008], prevalent heart diseases [3.81 (1.20-12.12), p=0.024] and underweight [5.15(1.30-20.39), p=0.020]. Determinants were largely similar with slightly different effect sizes for fixed cut-off based restrictive pattern.

Conclusion
Restrictive pattern was very frequent in this city.

Clinical implications
These results enhance the needs to increase the efforts to prevent and control tuberculosis, cardiovascular diseases and underweight in this setting.
Anti-MDA5 Antibody Dermatomyositis Overlap with Systemic Lupus Erythematosus: A Case Report and Review of the Literature
Authors: Milam Emily C. , Futran Jacobo , Franks Jr. Andrew G. 
Published: December 2016

Background:
Dermatomyositis (DM) is an autoimmune connective tissue disease that primarily targets the muscle, skin, and lungs. Many patients have autoantibodies that correspond to distinct clinical phenotypes. Melanoma differentiation-associated gene 5 (anti-MDA5) antibody, a specific antibody that targets the melanoma differentiation-associated gene 5 (MDA5), has been reported in DM cases and is significant for a distinct cutaneous presentation and rapidly progressive interstitial lung disease.

Objective:
Herein, we describe a patient with DM with a positive anti-MDA5 antibody and characteristic clinical phenotype, who subsequently developed coexisting systemic lupus erythematosus (SLE). A diagnosis of SLE was supported by his clinical phenotype, positive serologies, hypocomplementemia, and progression to glomerulonephritis and lupus cerebritis, features of which fulfilled the American College of Rheumatology criteria for SLE.

Conclusion:
DM is known to overlap with other autoimmune diseases, including SLE, and coexistence can lead to a wide variety of clinical presentations. SLE overlapping with anti-MDA5 positive DM may present with distinct clinical features.
Salvage Procedures for Management of Prosthetic Joint Infection After Hip and Knee Replacements
Authors: Mahmoud Samer S.S. , Sukeik Mohamed , Alazzawi Sulaiman , Shaath Mohammed , Sabri Omar 
Published: December 2016

Background:The increasing load placed by joint replacement surgery on health care systems makes infection, even with the lowest rates, a serious concern that needs to be thoroughly studied and addressed using all possible measures.Methods:A comprehensive review of the current literature on salvage procedures for recurrent PJIs using PubMed, EMBASE and CINAHL has been conducted.Results:Prolonged suppressive antibiotic therapy (PSAT), resection arthroplasty and arthrodesis were the most common procedures performed. Suppressive antibiotic therapy is based on the use of well tolerated long term antibiotics in controlling sensitive organisms. Resection arthroplasty which should be reserved as a last resort provided more predictable outcomes in the hip whereas arthrodesis was associated with better outcomes in the knee. Various methods for arthrodesis including internal and external fixation have been described.Conclusion:Despite good union and infection control rates, all methods were associated with complications occasionally requiring further surgical interventions.
Aggressive Early Debridement in Treatment of Acute Periprosthetic Joint Infections After Hip and Knee Replacements
Authors: Volpin Andrea , Sukeik Mohamed , Alazzawi Sulaiman , Haddad Fares Sami 
Published: December 2016

Background:Periprosthetic Joint Infection Remains a Dreaded Complication After Hip and Knee Replacement Surgery.Treatment Options for Acute Postoperative and Acute Hematogenous Infections Include Arthroscopic or Open Debridement With Retention or Exchange of the Prostheses. This Review Article Aims to Summarize the Evidence for Management of Acute Postoperative And Acute Hematogenous Infections.Methods:A Systematic Literature Search Was Performed Using a Computer-based Search Engine Covering Medline (OvidSP), PubMed Database (U.S. National Library of Medicine, National Institutes of Health), Embase, Web of Science, Cochrane and Google Scholar for Relevant Articles.Results:Common Themes Around Treatment of Acute Postoperative and Acute Hematogenous Infections Discussed in this Review Include the Timing of Intervention, Description of the Optimal Procedure and How we Perform it at our Institution, the Role of Arthroscopic Debridement, Most Commonly Isolated Micro-organisms and Prognostic Factors for Infection Control.Conclusion:Success in Treating Acute Postoperative and Acute Hematogenous Infections Depends on Early Diagnosis and Aggressive Surgical Debridement Combined With Effective Antibiotic Therapy.
Hydrocarbon Assessment and Prediction due to the Gulf War Oil Disaster, North Kuwait
Authors: Yihdego Yohannes , Al‐Weshah Radwan A. 
Published: December 2016

ABSTRACT: Oil spill in the Gulf was the biggest disaster in history. The scale of damage was enormous, ranging from destruction caused by oil fires and oil spills, to economic decline for the Kuwaiti oil industry. The transport modelling of the freshwater aquifers in north Kuwait was undertaken to assess potential remediation scenarios using the MODFLOW‐SURFACT numerical code. Three interlinked models were calibrated: flow, density (salinity), and transport. The model domain is a subregional area encompassing the Al‐Raudhatain and Umm Al‐Aish Basins. The time‐variant salinity transport model was calibrated simultaneously with the transient groundwater flow system and this includes variably saturated flow and transport. This was done prior to proceeding to simulate contaminant hydrocarbon transport, as the hydraulic gradients and flow directions (and storage volume) are significant controls on contaminant migration. The results depicted after 23 years and with respect to the total area of the freshwater body at Al‐Raudhatain (55.2 km2) and Umm Al‐Aish (37 km2); the areal extent of the total petroleum hydrocarbon plume is estimated to be 7.3 and 8.7 km2 for the 0.1 mg/L contour, respectively. This equates to total petroleum hydrocarbon impacting 13 and 24% of the Al‐Raudhatain and Umm Al‐Aish freshwater bodies, respectively. The simulation indicated that even though total petroleum hydrocarbon loading was negligible in the center of the Al‐Raudhatain depression up until the recent past, what has entered the groundwater system earlier from the contamination sources (pits, fringes, and lakes) is still moving toward the freshwater lenses or is potentially undetected due to lack of optimal existing monitoring bore screen and depth installations (plume diving). This implies that the environment is be the victim of war (the Gulf Crisis). The ecological and economic full impact probably will not be realized in the near future.
Le volet performance de la LOLF
Authors: Benzerafa Alilat Manel , Garcin Laurent , Gibert Patrick 
Published: December 2016

Le présent article est une synthèse des résultats d’un programme de recherche lancé en 2009 et porte sur les caractéristiques essentielles du genre créé par la mise en œuvre de la Loi organique relative aux lois de finances en ce qui concerne les projets annuels de performance. Ceux-ci améliorent la lisibilité de l’autorisation budgétaire mais ne révèlent qu’une faible finalisation de l’action publique par suite d’une altération très modérée de la logique politique. L’analyse des PAP donne l’impression d’une vision positiviste de la performance publique et d’intemporalité de nombreux programmes. Le genre construit par la pratique « lolfienne » représente davantage une innovation en matière de légitimation budgétaire et de communication financière qu’en matière d’innovation managériale.
La sélection de modèles lors de transitions vers des rôles émergents
Authors: Burellier Franck 
Published: December 2016

Cet article s’intéresse à la question de l’arrivée d’individus dans un nouveau rôle. En particulier, les auteurs s’intéressent aux modèles que les individus mobilisent lorsque ce rôle est émergent, peu stabilisé institutionnellement. Par une étude qualitative menée auprès de 19 commentateurs de jeux vidéo, rôle encore émergent en France, ils mettent en avant une typologie comprenant quatre modèles de rôle : les archétypes, les pairs, les analogues, et les homologues. Une discussion permet de souligner la spécificité des modèles lors de transitions vers des rôles émergents, ainsi que les modalités d’accompagnement qui faciliteraient ces transitions.
Reviews
Authors: Boddice Rob , Emden Christian J. , Vogt Peter 
Published: December 2016

Erin Sullivan, Beyond Melancholy: Sadness and Selfhood in Renaissance England
(Oxford: Oxford University Press, 2016), xiv, 227 pp.Sebastian Gießmann, Die Verbundenheit der Dinge: Eine Kulturgeschichte der
Netze und Netzwerke [The connectedness of things: A cultural history of
webs and networks] (Berlin: Kulturverlag Kadmos, 2014), 500 pp.Alexander Friedrich, Metaphorologie der Vernetzung: Zur Theorie kultureller
Leitmetaphern [A metaphorology of networks: Toward a theory of cultural
tropes] (Paderborn: Wilhelm Fink, 2015), 426 pp.Franziska Rehlinghaus, Die Semantik des Schicksals: Zur Relevanz des Unverfügbaren
zwischen Aufklärung und Erstem Weltkriek [The semantics of fate:
On the relevance of what is beyond human control between the Enlightenment
and World War I] (Göttingen: Vandenhoeck & Ruprecht, 2016),
479 pp.
Microsatellite markers for Nuphar japonica (Nymphaeaceae), an aquatic plant in the agricultural ecosystem of Japan
Authors: Kondo Toshiaki , Watanabe Sonoko , Shiga Takashi , Isagi Yuji 
Published: December 2016

Premise of the study:Nuphar species (Nymphaeaceae) are representative aquatic plants in irrigation ponds in Japanese agricultural ecosystems. We developed 15 polymorphic microsatellite markers for N. japonica and confirmed their utility for its close relatives N. oguraensis var. akiensis and N. ×saijoensis, which originated from natural hybridization between N. japonica and N. oguraensis.Methods and Results:Genetic variation was characterized in 15 polymorphic loci in three populations of N. japonica. The average number of alleles per locus was 3.47 (range = 2−9; n = 32), and the average expected heterozygosity per locus was 0.84 (range = 0.5–1.0); 11 loci were amplified in N. oguraensis var. akiensis and 15 in N. ×saijoensis.Conclusions:The polymorphic microsatellite markers developed in this study will be useful for investigating the levels of genetic diversity within remnant populations of Nuphar taxa and could provide a valuable tool for conservation genetics of these taxa.
Characterization of 16 microsatellite markers for the Oreinotinus clade of Viburnum (Adoxaceae)
Authors: Barish Syndi , Arakaki Mónica , Edwards Erika J. , Donoghue Michael J. , Clement Wendy L. 
Published: December 2016

Premise of the study:Microsatellite loci were isolated from four species of Viburnum (Adoxaceae) to study population structure and assess species boundaries among morphologically similar South American Viburnum species of the Oreinotinus clade.Methods and Results:Using a microsatellite‐enriched library and mining next‐generation sequence data, 16 microsatellites were developed. Each locus was tested on two populations of V. triphyllum and one population of V. pichinchense. For nuclear loci, one to 13 alleles were recovered, expected heterozygosity ranged from 0 to 0.8975, Simpson diversity index ranged from 0.0167 to 1.000, and Shannon diversity index ranged from 0 to 2.3670 in a given population. For the mitochondrial locus, three to six alleles were recovered and unbiased haploid diversity values ranged from 0.756 to 0.853 in a given population.Conclusions:The 16 microsatellite loci developed for the Oreinotinus clade (Viburnum, Adoxaceae) will inform investigations of population structure and species boundaries within this group.
HIGHMASS—HIGH H i MASS, H i-RICH GALAXIES AT Z ∼ 0: COMBINED H i AND H2 OBSERVATIONS
Authors: Hallenbeck Gregory , Huang Shan , Spekkens Kristine , Haynes Martha P. , Giovanelli Riccardo , Adams Elizabeth A. K. , Brinchmann Jarle , Carpenter John , Chengalur Jayaram , Hunt Leslie K. , Masters Karen L. , Saintonge Amélie 
Published: December 2016

ABSTRACT
We present resolved

and CO observations of three galaxies from the HIghMass sample, a sample of

-massive (

), gas-rich (

in the top 5% for their M
*) galaxies identified in the ALFALFA survey. Despite their high gas fractions, these are not low-surface-brightness galaxies and have typical specific star formation rates (SFR

) for their stellar masses. The three galaxies have normal SFRs for their

masses, but unusually short star formation efficiency scale lengths, indicating that the star formation bottleneck in these galaxies is in the conversion of

to

, not in converting

to stars. In addition, their dark matter spin parameters (λ) are above average, but not exceptionally high, suggesting that their star formation has been suppressed over cosmic time but is now becoming active, in agreement with prior Hα observations.