bluuebunny/crossref_metadata_2025_split huggingface dataset:
RELAÇÃO ENTRE INTENSIDADE DO QUADRO CLÍNICO DA COVID-19 EM PACIENTES COM DIABETES MELLITUS
Authors: Perez Pedro Augusto Chalup Simão , Sampaio Maria Nayara Ferreira , Sobrinho Ianca Alvez , Oliveira Gabriela Romano de 
Published: October 2024

O Diabetes Mellitus está entre as condições clínicas de risco para desenvolvimento de doenças com devido as consequências relacionadas a ação da insulina. A afecção por COVID-19 caracteriza-se pelo alto grau de infecciosidade, cujos sintomas incluem febre, fadiga, tosse, dispneia e sufocamento. Já o diabetes mellitus é uma condição crônica grave que ocorre quando o corpo não consegue produzir insulina suficiente ou não pode efetivamente usar a insulina que produz. Estando classificado em diabetes mellitus tipo 1, que ocorre a deficiência na produção de insulina, e, diabetes mellitus tipo 2 que ocorre a ação da insulina. A fisiopatologia do diabetes tipo 2 envolve uma combinação variável de resistência de insulina (principalmente no fígado e nos músculos) e uma diminuição da secreção de insulina pelas células beta pancreáticas. O objetivo deste artigo é apontar a relação de risco de quadro clínico desfavorável pela COVID-19 em pacientes diabéticos. O trabalho foi desenvolvido por meio de pesquisa bibliográfica qualitativa descritiva. A amostra foi composta por livros e artigos científicos que tratavam do tema. A busca dos materiais foi realizada em bibliotecas físicas e bibliotecas virtuais, principalmente em banco de dados da internet como Pubmed, SciELO e Google Acadêmico. Os resultados apontaram uma associação em que pessoa diabética tem maior risco desenvolver consequências desfavoráveis quando acometidas por COVID infeções devido às múltiplas complicações e imunidade comprometida. A infecção por SARS-COV-2 em pacientes diabéticos sem controle da hiperglicemia possuem maior associação de risco de evoluir para o quadro grave do COVID-19. Concluindo mostrou-se uma associação diabetes mellitus como um fator de risco para o prognóstico desfavorável da COVID-19.
PERFIL DE INAPTIDÃO SOROLÓGICA DE UM SERVIÇO DE HEMOTERAPIA DA CIDADE DE CASCAVEL- PR NO ANO DE 2023
Authors: Tonelli Velieltom , Debiazi Luana Portes , Ferreira Anderson Felipe , Horvath Barbara Sackser , Mecabô Grazielle 
Published: October 2024

Introdução: o ato transfusional é fundamental para o tratamento de uma série de patologias, tais como perdas volêmicas traumáticas e cirúrgicas, doenças crônicas e quadros oncológicos. Contudo, o risco de transmissão de patógenos por via hematológica é um importante fator a ser considerado na sistematização dos procedimentos hemoterápicos e na organização de medidas de biossegurança, a fim de reduzir ao máximo as chances de transmissão de doenças infecciosas. Objetivos: a presente pesquisa tem por objetivo caracterizar o perfil de inaptidão sorológica dos doadores de sangue do Hemocentro Regional de Cascavel no ano de 2023. Metodologia: trata-se de um estudo de natureza transversal e original, sob a modalidade pesquisa de campo e abordagem quantitativa, em que foram avaliados dados coletados dos bancos do Hemocentro Regional de Cascavel referentes ao sexo, idade e causa de inaptidão. Resultados e Discussão: obteve-se uma população de 15.531 doadores, com 312 indivíduos inaptos e 343 sorologias reagentes ou indeterminadas, com predomínio de mulheres entre 20 e 29 anos. Quanto à prevalência das sorologias triadas, a hepatite B foi a mais frequente, com 166 resultados reagentes, seguida pela sífilis, com 135 positividades. Considerações finais: diante do exposto, foi possível compreender o perfil epidemiológico de inaptidão sorológica no local e período avaliados, estas informações são importantes na consolidação de políticas de prevenção e promoção de saúde que visam a redução da transmissibilidade de patógenos e melhorias na biossegurança transfusional.
Mapping the evolution of liver aging research: A bibliometric analysis
Authors: Han Qun-Hua , Huang Shun-Mei , Wu Sha-Sha , Luo Sui-Sui , Lou Zhi-Yuan , Li Hui , Yang Yun-Mei , Zhang Qin , Shao Ji-Min , Zhu Li-Jun 
Published: October 2024

BACKGROUND
With the increasing of the global aging population, healthy aging and prevention of age-related diseases have become increasingly important. The liver, a vital organ involved in metabolism, detoxification, digestion, and immunity, holds a pivotal role in the aging process of organisms. Although extensive research on liver aging has been carried out, no bibliometric analysis has been conducted to evaluate the scientific progress in this area.
AIM
To analyze basic knowledge, development trends, and current research frontiers in the field via bibliometric methods.
METHODS
We conducted bibliometric analyses via a range of analytical tools including Python, the bibliometrix package in R, CiteSpace, and VOSviewer. We retrieved publication data on liver aging research from the Web of Science Core Collection Database. A scientific knowledge map was constructed to display the contributions from different authors, journals, countries, institutions, as well as patterns of co-occurrence keywords and co-cited references. Additionally, gene regulation pathways associated with liver aging were analyzed via the STRING database.
RESULTS
We identified 4288 articles on liver aging, authored by 24034 contributors from 4092 institutions across 85 countries. Notably, the years 1991 and 2020 presented significant bursts in publication output. The United States led in terms of publications (n = 1008, 25.1%), citations (n = 55205), and international collaborations (multiple country publications = 214). Keywords such as “lipid metabolism”, “fatty liver disease”, “inflammation”, “liver fibrosis” and “target” were prominent, highlighting the current research hotspots. Notably, the top 64 genes, each of which appeared in at least 8 articles, were involved in pathways essential for cell survival and aging, including the phosphatidylinositol 3-kinase/protein kinase B, Forkhead box O and p53 signaling pathways.
CONCLUSION
This study highlights key areas of liver aging and offers a comprehensive overview of research trends, as well as insights into potential value for collaborative pursuits and clinical implementations.
Bridging sentiment and finance: An exploration of BOD statements and bank ratios in Jordan
Authors: Kanakriyah Raed , Al-Faouri Abeer , Abuaddous Murad Y. , Alhindawi Riyad 
Published: October 2024

Purpose: This study explores the intricate interplay between sentiment extracted from Board of Directors (BOD) statements and the traditional financial metrics of banks. It investigates the relationship between a bank’s financial performance, measured by various financial ratios, and the sentiment expressed in BOD statements.Design/methodology/approach: Drawing from a dataset encompassing BOD statements from 15 Jordanian banks spanning 2017 to 2021, sentiment analysis techniques are employed to derive sentiment scores. These scores are then juxtaposed with principal components distilled from financial metrics to examine their predictive relationship.Findings: Preliminary findings reveal significant non-linear patterns between Hu and Liu’s (2004) sentimental analysis (Lui_sen), the Data Science Lab’s (n.d.) multilingual sentiment tool (multi_sen), and the principal components. A subsequent random-effects panel regression further elucidates these relationships, highlighting the significant influence of specific principal components on sentiment scores. This study provides a compelling case for integrating sentiment analysis with traditional financial indicators, offering a more comprehensive toolkit for evaluating bank performance.Research limitations/implications: Future research should explore broader datasets across multiple sectors, to validate the generalisability of the findings beyond the banking sector in Jordan.Practical implications: This research holds implications for investors, analysts, and stakeholders by combining sentiment analysis with traditional financial metrics. It offers deeper insights into the health of banks and the intentions of management. This integrated approach allows stakeholders to make informed decisions and mitigate risks based on a more comprehensive view of banks' financial situations. Additionally, the possibility of real-time sentiment analysis enables the dynamic monitoring of banking institutions' financial health as updated data becomes available.Social implications: The study’s results are valuable to users of financial information, aiding the Association of Banks and the Central Bank of Jordan in formulating policies for the banking sector. Auditors, consultants, and regulatory bodies in Jordan can also benefit from these insights.Originality/value: This is the first study exploring the relationship between sentiment extracted from BOD statements and traditional financial metrics in Jordan. It provides novel evidence of this relationship, contributing to the literature on the integration of textual data analysis and financial performance.
A la poursuite des maraîchers boliviens de Buenos Aires… Tours et détours méthodologiques pour aborder des acteurs qui se dérobent
Authors: Le Gall Julie 
Published: October 2024

Choisir d’étudier une population de migrants pose un certain nombre de défis méthodologiques que doivent relever les chercheurs en sciences sociales, quelle que soit leur discipline (géographie, anthropologie, sociologie...), notamment pour aborder les migrants sous l’angle biographique. Ainsi, avant même de commencer à mener des récits de vie, des entretiens directifs ou semi directifs, des enquêtes de type ethnologique, etc., il faut pouvoir entrer en confiance avec une population souvent méfiante. Or, paradoxalement, si les ouvrages méthodologiques décrivant ce type d’entretiens sont nombreux, aucun n’aborde leurs préliminaires, comme si les techniques d’approche dépendaient de l’ingéniosité de chaque chercheur, ou étaient propres à chaque terrain, aux migrants étudiés. Ne peut-on construire une méthode pour aborder les migrants à partir des récurrences tirées des expériences de chacun ?
Multiplexed Antibody Sequencing and Profiling of the Human Hemagglutinin-specific Memory B Cell Response following Influenza Vaccination
Authors: Raju Nagarajan , Kramer Kevin J , Cavallaro Mattia , Diotti Roberta A , Shiakolas Andrea R , Campos Mota Yailin , Richardson Robert A , Scheibe Ileia J , Ross Ted M , Georgiev Ivelin S , Sautto Giuseppe A 
Published: October 2024

Abstract
Influenza virus is a highly contagious respiratory pathogen causing between 9.4 and 41 million infections per year in the United States in the last decade. Annual vaccination is recommended by the World Health Organization, with the goal to reduce influenza severity and transmission. Ag-specific single B cell sequencing methodologies have opened up new avenues into the dissection of the Ab response to influenza virus. The improvement of these methodologies is pivotal to reduce the associated costs and optimize the operational workflow and throughput, especially in the context of multiple samples. In this study, PBMCs and serum samples were collected longitudinally from eight influenza vaccinees either vaccinated yearly for four consecutive influenza seasons or once for one season. Following the serological and B cell profiling of their polyclonal Ab response to a panel of historical, recent, and next-generation influenza vaccine hemagglutinin (HA) and virus strains, a single multiplexed Ag-specific single B cell sequencing run allowed to capture HA-specific memory B cells that were analyzed for preferential Ig H chain/L chain pairing, isotype/subclass usage, and the presence of public BCR clonotypes across participants. Binding and functional profiles of representative private and public clonotypes confirmed their HA specificity, and their overall binding and functional activity were consistent with those observed at the polyclonal level. Collectively, this high-resolution and multiplexed Ab repertoire analysis demonstrated the validity of this optimized methodology in capturing Ag-specific BCR clonotypes, even in the context of a rare B cell population, such as in the case of the peripheral Ag-specific memory B cells.
Current Status and Challenges of Interventional Therapy for Diagnosis and Treatment of Arrhythmia in China
Authors: Jiang Jiang , Zhang Shu 
Published: October 2024

Abstract
There are a large number of arrhythmia patients in China, and the field of interventional therapy for the diagnosis and treatment of arrhythmia has developed rapidly and made remarkable achievements. It is currently in a steady growth trend. In 2021, a total of 99,306 cases of pacemaker, 6547 cases of implantable cardioverter defibrillator, 5333 cases of cardiac resynchronization therapy, and 210,609 cases of catheter ablation were registered in the direct reporting system of arrhythmia interventional therapy information network, all of which increased significantly relative to those in 2020. However, there remains a considerable gap when in comparison with advanced countries. Therefore, there is an urgent need to widely implement and standardize advanced arrhythmia diagnosis and treatment techniques. In the future, it is vital to improve the training and development of arrhythmia physicians and teams, advance graded diagnosis and treatment, and foster international cooperation. In addition, there is a growing demand for increased clinical research to guide practical applications and the promotion of new technologies and devices for arrhythmia diagnosis and treatment.
Capítulo II: EL PROCEDIMIENTO DEL RECURSO ESPECIAL EN MATERIA DE CONTRATACIÓN, LAS MEDIDAS PROVISIONALES
Authors: Vicente Montalvo Pablo 
Published: October 2024

SUMARIO: 2.1. EL PROCEDIMIENTO EN EL RECURSO ESPECIAL EN MATERIA DE CONTRATACIÓN (REMC) 2.1.1. Anuncio del recurso y escrito de interposición 2.1.2. Vista de expediente y ampliación del recurso. La confidencialidad. 2.1.3. Subsanación requerida a la persona recurrente 2.1.4. Petición del expediente al órgano de contratación 2.1.5. Alegaciones de las personas interesadas 2.1.6. Práctica de la prueba 2.2. LA ADOPCIÓN DE MEDIDAS PROVISIONALES (MP) EN EL RECURSO ESPECIAL EN MATERIA DE CONTRATACIÓN 2.2.1. Solicitud de adopción de medidas provisionales: momento en el que se solicitan. La adopción de oficio por el Tribunal. 2.2.2. La suspensión automática del procedimiento de licitación. Solicitud de levantamiento por el órgano de contratación. Revisión de oficio por el Tribunal. La suspensión automática en la 2.2.3. Modificación o revocación de las medidas provisionales.contratación por lotes. 2.2.4. Garantías en la adopción de medidas provisionales. Pronunciamientos del TARCJA.
Da língua misógina do estupro ao corpo-resistência na literatura brasileira
Authors: Gomes Carlos Magno 
Published: October 2024

Neste estudo, defendemos o imaginário do assédio/estupro como próprio de uma língua misógina, composta por códigos que relativizam a violência sexual contra a mulher. Na literatura brasileira, observamos uma resistência a esse monolinguismo machista em obras que propõem o “corpo regenerado” em oposição ao “corpo estuprado”. Como corpus, analisaremos as estratégias estéticas de resistência do conto “Mulher cobra” (2018), de Sheila Smanioto, e dos romances Eu me possuo (2016), de Stela Florence, e Vista chinesa (2021), de Tatiana Salem Levy. Metodologicamente, exploramos o conceito de “corpo-território”, conforme Verónica Gago (2020), e a proposta de “carta-testemunho”, de Eurídice Figueiredo (2021), para obras que explicitam as diferentes etapas do estupro por meio do corpo abandonado, enlutado e/ou regenerado. Como resultado, identificamos uma literatura contra o silenciamento do estupro através de uma proposta estético-ideológica: o corpo-resistência.
Stability of Composition Caputa– Katugampola Fractional Differential Nonlinear Control System with Delay Riemann −Katugampola
Authors: Sami Ahmed , Sameer Qasim Hasan  
Published: October 2024

work used the Composition Caputo-Katugampola Fractional Derivatives technique to tackle nonlinear problems and delay fractional differential equations. The fractional derivative is defined using the Caputo and Riemann-Katugampola Fractional Derivatives Method. Proposed method In comparison to other digital technologies, this one is simple, effective, and uncomplicated. Ensure authenticity and correctness proposed method Some exemplary problems have been solved
Study of the structural and optical properties of pure copper oxide and doped with zinc at fixed weight percentages
Authors: Taher Wessam Mahmood , Ziad Mohamed Abood  , Abdulhussan Abas Khadayier  
Published: October 2024

Through this research, the effect of doping with zinc ions on the structural and optical properties of copper oxide particles doped with zinc at certain weight percentages was study using Radiofrequency plasma deposition technology. X-ray diffraction (XRD) analyses and field emission scanning electron microscopy were used to ascertain the materials' characteristics. Ultraviolet and visible spectroscopy of pure and doped thin films was also perform to calculate the band gap and electrical conductivity It was discovered using the XRD readings that the pure copper particles saturated with zinc had a crystalline size. It changes as Zn concentration rises and is influenced by the CuO lattice's strain and dislocation density. The thin film samples have structures resembling irregular and cubic grains, as demonstrated by the FE-SEM pictures. After doping with Zn, their homogeneity increases and adopts a regular granular nature. The band gap was also calculated for pure CuO particles as well as those doped with certain percentages of Zn. It was note that the addition of Zn worked to reduce Band gap for CuO
Effect of Probiotic Supplementation in Diet on Egg Production, Egg Quality, Intestinal Morphology and Bacterial Population in Caecum of Laying Hens
Authors: Puncharoen Sujeera , Poeikampha Theerawit , Poungpong Kanokporn 
Published: October 2024

The objective of this study was to study the effect of probiotic supplementation in diet on egg production, egg quality, intestinal morphology, and bacterial population in caecum of laying hens. A total of 768 Lohmann Brown-Classic laying hens, aged 42 - 54 weeks, were used. The laying hens were divided into 3 groups, each with 8 subgroups of 32 birds each. The experiment was planned to use a completely randomized design method. The 3 experimental groups were classified based on their dietary treatment as follows: 1) Basal diet (without probiotic supplementation), 2) Basal diet with probiotic 0.01 and 0.02 % in 3, respectively. Data was collected for 12 weeks. Adding probiotic in the diet was no significant difference on egg production, egg quality, and bacterial population in caecum. However, probiotic supplementation in the diet increased villi height of the duodenum significantly improved (p < 0.02), villi height per depth crypt of the duodenum significantly improved (p < 0.05), villi height per depth crypt of the jejunum significantly improved (p < 0.01), and villi height per depth crypt of the ileum significantly improved (p < 0.02). Therefore, studies have shown that dietary probiotic supplementation can improved small intestinal morphology are the most important indexes for measuring the digestive and absorption function of the small intestine are more efficient.
HIGHLIGHTS

Probiotic (Bacillus subtilis) is a gram-positive, non-pathogenic bacterium that can inhibit digestive enzymes such as protease, amylase, and lipase. These enzymes help increase the efficiency of digestion and absorption of nutrients.
As a result of the working mechanism of Bacillus subtilis, it helps strengthen the intestinal wall, eliminates pathogenic microorganisms, reduces damaged intestinal mucosal cells, and improves intestinal absorption, resulting in increased production.
Effect of probiotic (Bacillus subtilis) supplementation in laying hen diets on total bacterial load in appendix. No difference was found in the load of total bacteria and Escherichia coli (P > 0.05).
Its beneficial properties stimulate the growth of beneficial bacteria in the intestines, such as Bifidobacteria sp. and Lactobacillus sp., causing the production of lactic acid, which makes the colon more acidic, resulting in inhibition of the growth of pathogenic microorganisms.

GRAPHICAL ABSTRACT
Customer-Centric quality management: A framework for organizational excellence in SMEs
Authors: Nnenna Ijeoma Okeke  , Olufunke Anne Alabi  , Abbey Ngochindo Igwe  , Onyeka Chrisanctus Ofodile  , Chikezie Paul-Mikki Ewim  
Published: October 2024

In an era where customer expectations are continually evolving, Small and Medium Enterprises (SMEs) must adopt innovative quality management practices to achieve organizational excellence. This review presents a customer-centric quality management framework designed specifically for SMEs, emphasizing the pivotal role of customer satisfaction in enhancing operational efficiency, product quality, and overall business performance. The framework is built on the premise that customer feedback and engagement are integral to quality management processes. By prioritizing customer needs and expectations, SMEs can develop quality assurance strategies that not only meet but exceed customer requirements. This approach involves systematic collection and analysis of customer feedback, enabling organizations to identify areas for improvement and innovate their offerings accordingly. Central to the framework are key components such as continuous improvement, employee involvement, and process optimization. Continuous improvement methodologies, like Lean and Six Sigma, are tailored to suit the unique challenges faced by SMEs, fostering a culture of quality that empowers employees at all levels. Engaging employees in quality initiatives cultivates a sense of ownership and accountability, essential for driving organizational change and enhancing service delivery. Furthermore, the framework emphasizes the importance of aligning quality management practices with customer-centric strategies. This alignment ensures that quality initiatives are not only reactive but also proactive, anticipating customer needs and adapting processes to deliver superior value. Incorporating customer relationship management (CRM) tools enhances communication, allowing SMEs to gather insights that inform quality improvements and strengthen customer loyalty. Implementing a customer-centric quality management framework can significantly impact an SME's competitiveness by enhancing product reliability, reducing defects, and improving customer satisfaction. Ultimately, this approach fosters organizational excellence, leading to increased market share and long-term sustainability. In conclusion, this framework equips SMEs with the necessary tools to integrate customer-centricity into their quality management processes, driving continuous improvement and excellence.
Keywords: Customer-Centric Quality Management, Smes, Organizational Excellence, Customer Satisfaction, Continuous Improvement, Lean, Six Sigma, Employee Involvement, Process Optimization, CRM Tools, Competitiveness.