bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cumulative stressor exposure predicts menstrual cycle affective changes in a transdiagnostic outpatient sample with past-month suicidal ideation
Authors: Nagpal Anisha , Barone Jordan C. , Tauseef Hafsah , Ross Jaclyn , Gray Zach J. , Schmalenberger Katja M. , Shields Grant , Slavich George M. , Eisenlohr-Moul Tory 
Published: October 2024

AbstractBackgroundAffective responses to the menstrual cycle vary widely. Some individuals experience severe symptoms like those with premenstrual dysphoric disorder, while others have minimal changes. The reasons for these differences are unclear, but prior studies suggest stressor exposure may play a role. However, research in at-risk psychiatric samples is lacking.MethodsIn a large clinical sample, we conducted a prospective study of how lifetime stressors relate to degree of affective change across the cycle. 114 outpatients with past-month suicidal ideation (SI) provided daily ratings (n = 6187) of negative affect and SI across 1–3 menstrual cycles. Participants completed the Stress and Adversity Inventory (STRAIN), which measures different stressor exposures (i.e. interpersonal loss, physical danger) throughout the life course, including before and after menarche. Multilevel polynomial growth models tested the relationship between menstrual cycle time and symptoms, moderated by stressor exposure.ResultsGreater lifetime stressor exposure predicted a more pronounced perimenstrual increase in active SI, along with marginally significant similar patterns for negative affect and passive SI. Additionally, pre-menarche stressors significantly increased the cyclicity of active SI compared to post-menarche stressors. Exposure to more interpersonal loss stressors predicted greater perimenstrual symptom change of negative affect, passive SI and active SI. Exploratory item-level analyses showed that lifetime stressors moderated a more severe perimenstrual symptom trajectory for mood swings, anger/irritability, rejection sensitivity, and interpersonal conflict.ConclusionThese findings suggest that greater lifetime stressor exposure may lead to heightened emotional reactivity to ovarian hormone fluctuations, elevating the risk of psychopathology.
Impulsivity in first-degree relatives at risk of psychosis and mania: a systematic review and meta-analysis
Authors: Kerr-Gaffney Jess , Nuerzati Yahufu , Kopra Emma I. , Young Allan H. 
Published: October 2024

AbstractImpulsivity is elevated in psychosis and during mania in bipolar disorder. Studies in unaffected relatives may help establish whether impulsivity is a heritable, state independent endophenotype. The aim of this systematic review and meta-analysis was to examine whether impulsivity is elevated in unaffected relatives of those with bipolar disorder, schizophrenia, and schizoaffective disorder, compared to controls. Databases were systematically searched up until March 2023 for articles reporting data on a behavioral or self-report measure of impulsivity in first-degree relatives and controls. Nineteen studies were included. Behavioral (10 studies, d = 0.35, p < 0.001) and self-reported impulsivity was significantly elevated in bipolar disorder relatives compared to controls (5 studies, d = 0.46, p < 0.001), with small effect sizes. Relatives of those with schizophrenia did not show significantly elevated impulsivity compared to controls on behavioral measures (6 studies, d = 0.42, p = 0.102). There were not enough studies to conduct a meta-analysis on self-report data in schizophrenia relatives or schizoaffective disorder relatives (self-report or behavioral). Study quality was good, however there was moderate to high heterogeneity in behavioral meta-analyses. Results suggest elevated impulsivity may be an endophenotype for bipolar disorder, present in an attenuated state before and after the illness and in at-risk individuals. This trait, amongst other behavioral and psychological indices, could be used to identify those who are at risk of developing bipolar disorder. Future research should refine measurement across studies and establish which components of impulsivity are affected in those at risk of psychotic and bipolar disorders.
Associations of benzodiazepine use with cognitive ability and age-related cognitive decline
Authors: Osler Merete , Rozing Maarten Pieter , Wium-Andersen Ida Kim , Jørgensen Martin Balslev , Mortensen Erik Lykke , Okholm Gunhild Tidemann 
Published: October 2024

AbstractBackgroundIt remains uncertain whether long-term use of benzodiazepines is associated with age-related cognitive decline, and if cognitive ability in early life is the driver of any association. This study examines the association of cognitive ability in young adulthood with later use of benzodiazepines and explores whether the use of benzodiazepines during adult life is associated with cognitive decline in late midlife.MethodsThe study samples include cognitive tests on the Børge Priens Prøve (BPP) from the conscription board examination (age 19 years) from 335 513 men born 1949–1961 and data from re-examinations of 5183 men 44 years later. Cognitive decline was defined as the difference between scores at the conscription board and the re-examination. Information on purchases of benzodiazepines was obtained from the Danish National Prescription Registry, 1995–2022. Associations were analysed using Cox proportional hazards and linear regression.ResultsIn total, 120 911 (36%) men purchased benzodiazepines during a follow-up of 20 years. Lower cognitive scores in young adulthood were associated with a higher risk of initiating benzodiazepines (hazard ratio [95% CI] = 0.71[0.68–0.75]). Men with the highest cumulative use of benzodiazepines had larger cognitive decline (β-coefficient [95% CI] = −1.66 [−2.09 to −1.23] BPP scores) compared with never users. Current benzodiazepine users showed a larger cognitive decline than never users (β-coefficient [95% CI] = −2.42[−3.18 to −1.66] BPP scores) and this partially explained the above association. These estimates for cognitive decline were relatively small and may lack clinical relevance.ConclusionLow cognitive ability increases the risk of benzodiazepine use in adulthood and cognitive decline is more pronounced in those with the highest benzodiazepine use compared with never-use, but the difference lacks clinical significance.
The politics of direct taxation in Chile, 1870s-1890s: ¿“será defecto de la raza”?
Authors: Nazer Ahumada Ricardo , Llorca-Jaña Manuel 
Published: October 2024

AbstractThis article deals with a fiscal reform implemented in Chile during the late 1870s, when the country was suffering a severe economic and fiscal crisis, on the eve of the War of the Pacific. In 1879, the Chilean government introduced a new set of direct levies, taxing inheritance, income and wealth, despite the historic resistance of most of the economic elites to direct taxation in a highly unequal society. The process also shows that not all the economic elite avoided direct taxation. Despite other challenges faced by any developing country in extracting taxes from its population (e.g. lack of both proper information and human capital), during c.1879-1884 collection of these new direct taxes was successful, mainly on account of the improved extractive capacity built up during the preceding decades. Yet, by the mid-1890s all direct taxes (new and old) had been either derogated or transferred to local government (in some cases after being modified). Once again, Chilean central government depended entirely on indirect taxes, with export duties on nitrate being the most important. Nitrate provides a good example of an export boom shaping taxation for the worse; rather than increasing and diversifying the sources of revenue, a dominant sector of the Chilean economic elite decided to stop paying direct taxes and to make the state entirely dependent on the cycles of the international economy. However, some members of the economic elite, although defeated in their purpose, were aware of the wide range of benefits of keeping direct taxation: social justice, financial health and less vulnerability to trade cycles. Unfortunately, the balance of power favoured elite groups with enough power to hinder direct taxation.
Teaching Pathographies of Mental Illness
Authors: Carlin Nathan , Gomez Angela , Ortiz Margarita 
Published: October 2024

Abstract
This paper describes the content and evolution of a fourth-year course for medical students on teaching pathographies of mental illness. (It is a follow-up to Nathan Carlin’s Pathographies of Mental Illness that appeared as an Element in the Bioethics and Neuroethics series published by Cambridge University Press.) The course originally centered on classic (and some contemporary) memoirs; however, responding to student evaluations, newer material now ensures more diversity, with material written by women and people of color, and describes the difference that can make.
Surgical outcome of the borderline hypoplastic left ventricle: impact of the left ventricle rehabilitation strategy
Authors: Cheng Haonan , Osawa Takuya , Palm Jonas , Schaeffer Thibault , Heinisch Paul Philipp , Piber Nicole , Röhlig Christoph , Meierhofer Christian , Georgiev Stanimir , Hager Alfred , Ewert Peter , Hörer Jürgen , Ono Masamichi 
Published: October 2024

AbstractObjective:This study aims to assess the surgical outcome of borderline hypoplastic left ventricle before and after the induction of the left ventricle rehabilitation strategy.Methods:A retrospective review investigated patients with borderline hypoplastic left ventricle who underwent surgical intervention between 2012 and 2022. The patient cohort was stratified into two groups based on the initiation of left ventricle rehabilitation: an early-era group (E group, 2012–2017) and a late-era group (L group, 2018–2022). Left ventricle rehabilitation was defined as palliation combined with other procedures aimed at promoting left ventricular growth such as restriction of atrial septal defect, relief of inflow/outflow obstructive lesions, and resection of endocardial fibroelastosis.Results:A total of 58 patients were included. Primary diagnosis included 12 hypoplastic left heart syndromes, 11 critical aortic valve stenosis, and others. A total of 9 patients underwent left ventricle rehabilitation, 8 of whom underwent restriction of atrial septal defect. As for clinical outcomes, 9 of 23 patients achieved biventricular repair in the E group, whereas in the L group, 27 of 35 patients achieved biventricular repair (39% vs. 77%, p = 0.004). Mortality did not differ statistically between the two groups (log-rank test p = 0.182). As for the changes after left ventricle rehabilitation, left ventricular growth was observed in 8 of 9 patients. The left ventricular end-diastolic volume index (from 11.4 to 30.1 ml/m2, p = 0.017) and left ventricular apex-to-right ventricular apex ratio (from 86 to 106 %, p = 0.014) significantly increased after left ventricle rehabilitation.Conclusions:The introduction of the left ventricle rehabilitation strategy resulted in an increased proportion of patients achieving biventricular repair without a concomitant increase in mortality. Left ventricle rehabilitation was associated with enhanced left ventricular growth and the formation of a well-defined left ventricle apex. Our study underscores the significance of left ventricle rehabilitation strategies facilitating successful biventricular repair. The data suggest establishing restrictive atrial communication may be a key factor in promoting left ventricular growth.
Kant on the Despotic Danger of a World State
Authors: Fang Bo 
Published: October 2024

AbstractIn this article, I argue that Kant’s real reason for rejecting a world state in practice is that a world state would be in greater danger of despotism than individual states. Kant hopes that public participation and self-enlightenment of the people in the public sphere could counter the despotic danger in individual states. However, in a world state, state affairs are too distant from the lives of individuals, making it difficult for individuals to maintain enthusiasm for public discourse and political enlightenment. Moreover, the absence of external competition and the risk of war would eliminate the incentive of the ruler to preserve freedom for the development of industry and commerce and, consequently, for the enlightenment of the people. These defects make it more difficult for a world state to resist despotic danger.
The concept of service model fidelity in Talking Therapies
Authors: Cromarty Paul 
Published: October 2024

Abstract
The concept of Service Model Fidelity is considered as a parallel process to Treatment Fidelity in evidence-based psychological therapies. NHS Talking Therapies (formerly IAPT) aimed to increase access to an expanded, upskilled workforce on a national scale. This included systematic training, supervision and front-line service delivery, emphasising treatment fidelity to evidence-based interventions. A further feature of NHS Talking Therapies was modernising and restructuring of the health system that housed these trained practitioners. The term ‘service model fidelity’ (Cromarty, 2016) was coined to emphasise service modernisation aspects as a distinct entity. A definition of the latter is included. Examples of service model fidelity and of service model drift, are outlined to distinguish these from therapist drift. This links to past literature recommending changes in traditional mental health service design and emergent evidence from NHS Talking Therapies. The latter examines publicly available data identifying characteristics of service design, which appear to be predictors of enhanced clinical outcome. Challenges in modernising health systems are discussed and conclusions are made highlighting the crucial role of service model when delivering evidence-based therapies. Suggestions for further research into service configuration to improve experiences of service users are considered. This includes ongoing exploration of service design being more than a qualitative feature, and increasingly appearing as a key factor in enhanced clinical outcome.

Key learning aims

(1)
To identify service model fidelity as separate entity to treatment fidelity.

(2)
To provide a clear definition of service model fidelity.

(3)
To delineate therapist drift from service drift.

(4)
To further examine the role of service model in delivering evidence-based interventions.
Forging support: when there is no alternative to ‘there is no alternative’
Authors: Joosten M.A. (Max) 
Published: October 2024

AbstractWhether fiscal austerity by governments is unpopular or not is much discussed in the literature. One line of research argues that consolidation has negative electoral effects, ranging from declines in politicians’ approval ratings to abstention by voters at elections. Another strand highlights that re-election chances are not harmed by the implementation of austerity and that some voters in fact support consolidation measures. Both sides are limited in at least two regards. First, they do not allow for the possibility that public opinion is shaped by the political discussion about government debts and budget deficits. Second, and relatedly, the literature is limited in its extent to which it considers heterogeneity in preference adaptation across income groups. This article contributes to these debates by bringing to bear insights from the literature on mass preference formation. In particular, I argue that a cross-party consensus on austerity leads voters to align their preferences with the consensus, increasingly demanding cuts to government spending. This adaptation is conditioned by income so that the preferences of those income groups that are the furthest away from the consensus adapt their fiscal preferences most. By including the discursive context of fiscal policy, this article helps explain how austerity can be made popular. Empirically, I test these expectations by matching citizen preferences with party positions on fiscal policy for 60 country years. The empirical results indeed demonstrate that even though low- and middle-income voters are least supportive of austerity, they adapt the most to the party consensus on austerity.
Breaking Water Laws in the Murray‐Darling Basin: Understanding Water Compliance Challenges and Stakeholder Perceptions
Authors: Seidl Constantin , Wheeler Sarah Ann 
Published: October 2024

AbstractClimate change will put pressure on irrigated agriculture, increasing water scarcity and possible non‐compliance with water regulations. This is especially true in areas such as the Murray‐Darling Basin (MDB), Australia, an area where water resources have been overallocated. Understanding the expected penalties and probability of detection and prosecution of water theft faced by irrigators is important for understanding the incentives for water compliance. We analyze state‐level compliance action data and undertake a detailed case study of estimating the real penalty value of water theft in New South Wales (NSW), the largest MDB state. This analysis is supplemented with qualitative comment on compliance issues from 63 MDB stakeholder interviews. Although findings from random audits suggest that only a small percentage of irrigators commit water theft offenses, the average probabilities of audit detection and prosecution for water theft in NSW between 2018/19 and 2020/21 were low, leading to an average real expected penalty value of stealing water well below existing market prices. Stakeholder interviews confirmed that the majority did not believe there were serious water theft or water compliance challenges—whereas recent secondary survey data suggests that the general public perceives water theft and compliance as a serious and ongoing challenge in the MDB and more needs to be done to address it. Three recommendations for data and policy reform are proposed, namely: (a) improving compliance data and reporting; (b) increasing the probability of detection and prosecution; and (c) increasing penalties, regulator visibility, and reforming legislation. Results illustrate that even countries with highly advanced water governance require data improvements, along with sufficient levels of compliance activities and penalties for effective deterrence and stakeholder confidence.
Non‐Typical Supershear Rupture: Fault Heterogeneity and Segmentation Govern Unilateral Supershear and Cascading Multi‐Fault Rupture in the 2021 Mw ${M}_{w}$7.4 Maduo Earthquake
Authors: Hayek J. N. , Marchandon M. , Li D. , Pousse‐Beltran L. , Hollingsworth J. , Li T. , Gabriel A.‐A. 
Published: October 2024

AbstractPrevious geodetic and teleseismic observations of the 2021 7.4 Maduo earthquake imply surprising but difficult‐to‐constrain complexity, including rupture across multiple fault segments and supershear rupture. Here, we present an integrated analysis of multi‐fault 3D dynamic rupture models, high‐resolution optical correlation analysis, and joint optical‐InSAR slip inversion. Our preferred model, validated by the teleseismic multi‐peak moment rate release, includes unilateral eastward double‐onset supershear speeds and cascading rupture dynamically triggering two adjacent fault branches. We propose that pronounced along‐strike variation in fracture energy, complex fault geometries, and multi‐scale variable prestress drives this event's complex rupture dynamics. We illustrate how supershear transition has signatures in modeled and observed off‐fault deformation. Our study opens new avenues to combine observations and models to better understand complex earthquake dynamics, including local and potentially repeating supershear episodes across immature faults or under heterogeneous stress and strength conditions, which are potentially not unusual.
Long Distance Transport of Subsurface Sediment‐Derived Iron From Asian to Alaskan Margins in the North Pacific Ocean
Authors: Sieber M. , Lanning N. T. , Steffen J. M. , Bian X. , Yang S.‐C. , Lee J. M. , Weiss G. , Hunt H. R. , Charette M. A. , Moore W. S. , Hautala S. L. , Hatta M. , Lam P. J. , John S. G. , Fitzsimmons J. N. , Conway T. M. 
Published: October 2024

AbstractThe international GEOTRACES program has been instrumental in demonstrating how marine sediments are a critical source of dissolved Fe to the world's oceans. Here, we present dissolved iron (dFe) from the GEOTRACES North Pacific GP15 section, which, alongside other sediment‐source tracers (including dissolved δ56Fe, Mn, 228Ra, and particulate Fe), allows for identification of the dFe provenance of three distinct dFe depth maxima at the Alaskan margin. Two of these (shelf and abyssal depths) are of local Alaskan sedimentary origin. The third, a mid‐depth dFe maximum with an absence of 228Ra, is an advected signal that, based on tracer data from Western Pacific GEOTRACES transects and circulation models, must be advected from sedimentary sources on the Asian margin, ∼5,000 km away. This study illustrates the importance of measuring diagnostic sedimentary tracers like radium when assigning local margins as sedimentary sources of marine trace metal budgets.
Detecting Instantaneous Tidal Signals in Ocean Models Utilizing Streaming Band‐Pass Filters
Authors: Xu Chengzhu , Zaron Edward D. 
Published: October 2024

AbstractThrough the implementation of a streaming filter, output of numerical ocean simulations can be band‐pass filtered at tidal frequencies while the model is running, yielding time series of sinusoidal motions consisting of tidal signals in the filter's target frequency band. The filtering algorithm is developed from a system of two ordinary differential equations that represents the motion of a damped harmonic oscillator. The filter's response to a broadband input signal is unity at its target frequency but vanishes toward the low and high frequency limits. The decay of the filter response is controlled by a dimensionless parameter, which determines the filter's bandwidth. As a result, the filter allows signals within a small frequency band around its target frequency to pass through, while blocking signals outside of its target frequency band. In this work, the filtering algorithm is implemented into the barotropic solver of the Modular Ocean Model version 6 (MOM6) for determining the instantaneous tidal velocities of the semi‐diurnal and diurnal tides. Utilizing the filters, the frequency‐dependent internal wave drag is applied to the semi‐diurnal and diurnal frequency bands separately. The simulation results suggest that the performance of the algorithm is consistent with the filter transfer function in Fourier space. Potential applications of the algorithm also include de‐tiding the model output for nested regional ocean models, especially those for the purpose of operational forecasting.