bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring arteriolar atherosclerosis: laminar blood flow across stenosis with fluid-structure interaction and gravitational effects
Authors: Narayan S Shankar , Animasaun Isaac Lare , Muhammad Taseer 
Published: September 2024

Abstract
In response to the unanswered relevant questions surrounding atherosclerosis, it becomes imperative to investigate arterioles using sophisticated mathematical modelling techniques to shed light on critical stress and strain patterns influenced by gravity. The primary objective of this study is to scrutinize flow characteristics and probe stress and strain distributions experienced by the intima layer of arterioles, encompassing coronary, renal, cerebral, mesenteric, and pulmonary arteries, under gravitational forces. This investigation employs a fluid-structure interaction methodology utilizing arbitrary Eulerian–Lagrangian formulation. The study delves into blood flow characteristics within coronary, renal, cerebral, mesenteric, and pulmonary arterioles using the fluid-structure interaction technique, employing an arbitrary Eulerian–Lagrangian formulation. It thoroughly examines various biomechanical parameters such as the Cauchy–Green stress tensor, Principal strain, Piola–Kirchoff stress tensor, deformation tensor, and volume strain along the intima layer under the gravitational influence, elucidating vulnerable regions prone to endothelial dysfunction. Higher values of δV are found at the left shoulder and in the intima’s post stenosis area due to the pressure gradient along the flow channel, whereas other intima regions show a null volume strain. A thorough understanding of stress distribution is essential to create focused therapies to lessen vascular health problems. The stress in the post-stenosis region seems to affect the endothelial layer to a significant extent.
Understanding French Conversational Implicatures by Foreign Language Study Program Students
Authors: Urip Sri Rejeki , Pudjitriherwanti Anastasia , Umam Khotibul 
Published: September 2024

Learners of French as a foreign language are expected to be able to use French as French native speakers (bien français). In communication, not all meaning comes from the words spoken. Speeches that contain things like this are called conversational implicatures. Understanding foreign language conversational implicatures is difficult. Learners are required for this ability to be able to communicate like native speakers. The present study intends to know to what extent learners understand conversational implicatures. This study follows Bouton and Pratama's research examining the understanding of conversational implicatures in English as a second language. Respondents of this research were 55 students studying French as a foreign language. In collecting the data, three types of tests were used, namely: (1) a Test of Conversational Implicatures, (2) a Test of Vocabulary Mastery, (3) and Test of Structure Mastery. There are 30 questions about 10 types of conversational implicatures, 30 vocabulary questions, and 30 structure questions. The results of the study revealed that there were 8 questions answered incorrectly by more than 50% of respondents. It also shows that the most difficult types of Conversational Implicature are (a) Indirect Criticism, followed by (b) Quantitative, (c) Qualitative, (d) Manner, and (e) MRR. By using Multiple Linear Regression Analysis, statistically it is revealed that vocabulary and structure mastery contributes to Conversational Implicatures understanding.
Le Registre Publicitaire et Les Fonctions du Langage dans Les Publicités de Mc Donald’s: La Perspective Sociolinguistique
Authors: Alhurriyah Nida , Urip Sri Rejeki , Arsiyana Marliza , Pudjitriherwanti Anastasia 
Published: September 2024

Cette recherche vise à identifier et décrire les formes de registres publicitaires et la fonction du langage dans le registre publicitaire de publicités Mc Donald’s en français. Les données de cette recherche sont des mots et des syntagmes dans les publicités Mc Donald’s qui sont téléchargées de décembre 2020 à octobre 2021. Cette recherche utilise la méthode descriptive qualitative. Les résultats de cette recherche ont rélévé 52 registres publicitaires français dans les publicités Mc Donald’s qui se composent de 27 mots et 25 phrases. Les registres publicitaires français ont été analysés des catégories gramaticales et le sens denotatifs. Le catégoties gramaticales existe six catégories grammaticales. Les catégories grammaticales sont : le nom, le verbe, l’adjectif, l’adverbe, la préposition et l'introducteur, dont certains sont formés de l’abréviation et l’emprunt à l’anglais. En plus, le registre publicitaire ont révélé cinq fonctions du langage, à savoir : la fonction régulatrice, fonction représentative, fonction personnelle, fonction imaginative, fonction interactionnelle. La catégorie grammaticale la plus dominante est le nom, car de nombreux mots et expressions dans le domaine de la publicité consistent en des noms de produits ou de services offerts par Mc Donald’s. En plus, la fonction la plus dominante du langage est la fonction du langage régulatrice, car la fonction du langage régulatrice est d'exprimer une invitation, une séduction, un appel ou une commande en accord avec le domaine de la publicité.
PERMAFROST-LANDSCAPE CONDITIONS OF THE BOLSHEZEMEL'SKAYA TUNDRA AND THEIR MAPPING BASED ON REMOTE SENSING DATA
Authors: ОСАДЧАЯ Г.Г. , ПИЖАНКОВА Е.И. 
Published: September 2024

На основе мерзлотно-ландшафтных крупномасштабных исследований значительной части Большеземельской тундры и дешифрирования среднемасштабных космических снимков (Landsat-7) составлена ее обзорная геокриологическая карта масштаба 1:1 000 000, охватывающая площадь 136 700 км2. За основу принят метод ландшафтной индикации, реализованный применительно к геокриологическим подзонам. Пространственная изменчивость геокриологических характеристик получила отражение на уровнях природных подзон и групп доминирующих урочищ.
An overview geocryological map (1:1 M scale) for an area of 136 700 km2 covering a significant part of the Bolshezemelskaya tundra was compiled on the basis of large-scale field permafrost-landscape surveys and interpretation of medium-resolution Landsat-7 satellite images. The method of landscape indication implemented in relation to geocryological subzones was used. Spatial variability of geocryological characteristics was analyzed at the levels of natural subzones and groups of dominant landscape units.
Hospital Variations and Temporal Trends in Procalcitonin Use for Patients With Bronchiolitis
Authors: Bakkum Kathryn , Pelletier Jonathan , Rajbhandari Prabi 
Published: September 2024

BACKGROUND AND OBJECTIVE
The financial burden of bronchiolitis-related hospitalizations in the United States surpasses $700 million annually. Procalcitonin (PCT) has garnered recent interest in pediatrics and has demonstrated the potential to decrease antibiotic usage in other illnesses. This study assessed PCT utilization trends in bronchiolitis, hypothesizing an annual increase in PCT testing.

METHODS
We conducted a multicenter, retrospective cross-sectional study utilizing the Pediatric Health Information Systems database. Infants aged 2 to 23 months presenting with bronchiolitis from January 1, 2016, to December 31, 2022, were included. Encounters with and without PCT testing were compared using χ2 testing and Wilcoxon rank-sum testing as appropriate. Temporal trends in PCT testing and correlations with hospital-level proportions of PCT use, antibiotic administration, and admission proportion were assessed using Spearman’s ρ.

RESULTS
There were 366 643 bronchiolitis encounters among 307 949 distinct patients across 38 hospitals during the study period. Of those, 1.5% (5517 of 366 643) had PCT testing performed. PCT usage increased more than 14-fold between 2016 and 2022 (0.2% in 2016 vs 2.8% in 2022, ρ &gt; 0.99, P &lt; .001). PCT use ranged from 0.01% to 8.29% across hospitals. The hospital-level proportion of PCT testing was not associated with admissions (ρ = 0.13, P = .42) or antibiotic use (ρ = 0.31, P = .06).

CONCLUSIONS
PCT testing in patients with bronchiolitis increased 14-fold between 2016 and 2022 and was not associated with decreased antimicrobial prescriptions. Further studies are needed to determine the diagnostic yield of PCT in bronchiolitis.
Evaluation of the use of a photovoltaic installation in the autumn and winter in the aspect of climate change
Authors: Stanek Paulina , Leśny Jacek , Leszek Kuchar , Ewa Broszkiewicz-Suwaj Ewa 
Published: September 2024

Cel pracyW obliczu nieuchronnej zmiany klimatu, oraz wysokiego zapotrzebowania na energię w okresie grzewczym (październik – marzec), podjęto próbę oszacowania zmiany dostępnego promieniowania całkowitego w perspektywie 60 lat (2000 – 2060)Materiał i metodyDo szacowania promieniowania wykorzystano 5 wzorów bazujących na standardowych danych meteorologicznych (temperatura, opad), dla których parametry wyznaczono na podstawie rzeczywistych obserwacji pochodzących z Wrocławia, który jest dobrym reprezentantem południowej, nizinnej części Polski. Wartości opadu i temperatury dla roku 2060 i scenariusza RCP 6.0 oraz tła (roku 2000) uzyskano przy pomocy generatora danych meteorologicznych WGENK.Wyniki i wnioskiUzyskane rezultaty wskazują, że przy spodziewanym wzroście temperatury i opadów, promieniowanie całkowite może zmniejszyć się o 5% w okresie październik – marzec w roku 2060 w porównaniu do roku referencyjnego 2000.
Differences of interference myogram patterns from forearm muscles at different variants of the hand grip
Authors: Eliseichev E. A. , Tyaptin A. A. , Zhilin R. M. , Vorobyev P. S. , Blinov I. S. 
Published: September 2024

Background. Most modern bioprostheses use two sensors located on the flexor and extensor muscles of the hand and fingers to register muscle activity, which severely limits the functionality of the device and complicates switching between grips. One of the solutions to this problem is to use an array of more sensors to recognize different grips using a neural network.Aim. To evaluate the possibility in principle of using an array of 8 sensors for recognizing different grips.Materials and methods. Research was conducted on 23 healthy volunteers, whose surface myograms were recorded at 13 different grips. An array of surface-type electroneuromyographic sensors (n = 8) with bipolar electrodes and electroneuromyographic signal amplification factor of 2000 times, myograph and software are of own development were used as a technical base for the research.Results. For most subjects, the differences in the investigated parameters when comparing grips with each other reached thousands of percent, especially when comparing the product of frequency and mean amplitude. In some pairs the differences were less significant and amounted to less than 400 %. The proportion of pairs with reliable differences varies from subject to subject when comparing the product of frequency and mean amplitude and ranges from 71 to 98 %. The average value for the whole group is 87 %. When comparing frequency only, the variation ranges from 67 to 93 %, with an average of 78 %.Conclusion. For most subjects, the majority of grips are confidently differentiated from each other. Due to pronounced individual peculiarities, the decision to use this or that parameter to control the bioprosthesis for a definite person is individual and should be made after a thorough neurophysiological research. Some people will require training in order to develop a new motor stereotype.
Pengembangan Bahan Ajar E-Magazine dengan Pendekatan SAVI pada Materi Dinamika Litosfer dan Dampaknya Terhadap Kehidupan
Authors: Nurhasanah Nurhasanah , Handoyo Budi , Irawan Listyo Yudha 
Published: September 2024

The development of 21st century education affects the use of learning media. In learning activities, digital teaching materials are needed that support the student's learning process. The development of e-magazine teaching materials for lithosphere dynamics materials is carried out because digital teaching materials are minimally used in learning. The purpose of this research is to produce e-magazine teaching materials with the SAVI approach. This study used the ADDIE (Analyze, Design, Development, Implementation, and Evaluation) model procedure. The types of data used are quantitative and qualitative. In the process of collecting data using questionnaires, interviews, as well as documentation of activities with percentage descriptive data analysis techniques. Teaching material products are tested for feasibility at SMA Negeri 2 Malang class XI IPS 3. Based on the results of product feasibility tests by media expert validators, material experts, linguists and test results in schools, e-magazine teaching materials are very feasible and valid for geography learning.
Kepesertaan Wajib Badan Penyelenggara Jaminan Sosial dalam Perspektif Hukum Persaingan Usaha
Authors: Pratiwi Galuh 
Published: September 2024

This study highlighted the issue of arrangement for mandatory BPJS (Indonesian national health insurance) membership from the perspective of competition law. The research method used in this study was the normative juridical method, and the statute approach was employed. The results of the study indicated that the establishment of BPJS was mandated by the Law on National Social Security System (UU SJSN) and Law on National Health Insurance (UU BPJS); therefore, BPJS arrangement for mandatory membership is a permissible form of monopoly. The government monopoly through BPJS in administering health insurance is an obligation, instead, because the contribution of social security is in fact the same as taxes.Keywords: BPJS mandatory membership; competition law Penelitian ini mengangkat permasalahan mengenai pengaturan kepesertaan wajib BPJS dalam perspektif hukum persaingan usaha. Metode penelitian yang digunakan dalam penelitian ini adalah yuridis normati. Pendekatan yang dipergunakan dalam penelitian adalah pendekatan perundang-undangan (statute approach). Hasil penelitian menunjukkan bahwa pembentukan BPJS merupakan amanat UU SJSN dan UU BPJS, sehingga pengaturan BPJS mengenai kepesertaan wajib BPJS merupakan bentuk monopoli yang diperbolehkan. Monopoli pemerintah lewat BPJS dalam penyelenggaraan jaminan kesehatan justru bentuk keharusan karena kontribusi jaminan sosial sesungguhnya sama dengan pajak.Kata-kata Kunci: Kepesertaan wajib BPJS; hukum persaingan usaha
Synthesis, diagnosis as well as Biological activity studies of some metal ion complexes of Schiff Bases Derived from 4-aminoantipyrine
Authors: F. Mohammed Amera , A.Saeed Israa , Sh.AL-Nama Khansaa 
Published: September 2024

قواعد شيف متعددة السن ذوات الصيغة L1= اورثو هايدروكسي انيلين -٤ - امینو انتبيرين N',N) بنزیلیدین) تم تحضيرها من تكثيف البنزايل و٤-امينو انتيبرين مع ۲-امينو فينول -۲،۱ امينو ٤ كلورو فينول بنسبة مولية (١:١:١) لكل مكون . واستخدمت هذه الليكاندات لتحضير المعقدات ذوات الصيغة [ML1 Cl]Cl و [ML2]Cl2 حيث ان Zn(II) M= Mn(II), Co(II), Ni(II),. تم استخدام التقنيات التالية لتشخيص الليكاندات والمعقدات: مطيافية الاشعة فوق البنفسجية والاشعة تحت الحمراء - المرئية وطيف الرنين النووي المغناطيسي للبروتون 1HNMR والتحليل الدقيق لايونات العناصر والكاربون والهيدروجين والنتروجين بالاضافة الى التوصيلية الكهربائية المولارية وقياسات الحساسية المغناطيسية. دلت القياسات التي تم الحصول عليها من التوصيلية الكهربائية المولارية والتي تم اجراؤها بمحلول DMSO ان جميع معقدات (L1) كانت الكتروليتية بنسبة (١:١) بينما معقدات (L2) كانت الكتروليتية بنسبة (1:2). كما اظهرت نتائج القياسات المستخدمة في هذه الدراسة ان مواقع التناسق لليكاند (L1) مع الأيون المركزي كانت من خلال ذرة الاوكسجين الفينولية وذرتين نيتروجين لمجموعتي الازوميثين اما بالنسبة لـ (L2)فبالاضافة للذرات المانحة المذكورة سابقا يتم التناسق مع ذرة الاوكسجين لمجموعة الكاربونيل الطرفية. جميع المعقدات اظهرت التناسق الرباعي بشكل هندسي رباعي السطوح ايضا تمت دراسة الفعالية البايولوجية للمركبات المحضرة ضد البكتريا موجبة الكرام (+)Staphylococcus aurous وسالبة الكرام (-) Klebsiella pneumonia.
Minority of a deed provided for by the criminal law: praxis legis, guae debet esse
Authors: Sverchkov V. V. 
Published: September 2024

Objective: to develop scientifically substantiated provisions on the insignificance of a deed provided for by the criminal law and to propose measures to improve legislation and law enforcement in this area. Methods: dialectical approach to cognition of social phenomena, allowing to analyze them in development and functioning, which contributed to the use of the following research methods: a) general scientific (logical, systemic, analysis and synthesis, induction and deduction), b) special (documentary, practical, comparative-legal, formal-legal). Results: the work substantiates the conclusion that the recognition by an inquirer, investigator, prosecutor, judge of the insignificance of a deed provided for by the criminal law should be based on the following information: about the occurrence of all elements and signs of corpus delicti in the deed; about the infliction of small (minor) harm to law-protected interests in conjunction with the intent of the perpetrator aimed at causing such, including the lack of desire to cause harm, which excludes the existence of a reasonable amount of criminal-law harm. It is proposed to supplement Part 1 of Article 24 of the Russian Criminal Procedure Code with a new ground for refusal to initiate criminal proceedings (termination of criminal proceedings), namely, the insignificance of the deed, and to consider it as a circumstance excluding criminal prosecution of a suspect (accused). Scientific novelty: the following means to distinguish a minor act from a crime were substantiated: a) the introduction of the “reasonable amount of criminal-legal harm” category in the investigative and judicial practice, b) the need for law enforcement to establish objective and subjective conditions of minor significance of the deed, c) the proposal on modernizing the criminal-procedural legislation. Practical significance: the main provisions and conclusions stated in the article can be used in scientific, pedagogical, law-making, investigative and judicial activity when considering the issues of application and improvement of the norm on the insignificance of a deed provided for by the criminal law, on the delimitation of such deed from a crime.
Challenges and Solutions in Implementing Electronic Prescribing: A Qualitative Study
Authors: Borhani Neda , Hooshmand Elahe , Zarqi Marzie , Meraji Marziyhe 
Published: September 2024

Abstract

Background
The use of electronic prescribing is recognized as a strategic tool for improving healthcare. Given the nationwide implementation of electronic prescribing systems initiated in 2020, this study aims to explore the challenges and solutions for implementing electronic prescribing in Iran's health system as a developing country.
Methods
This qualitative study was conducted through interviews with physicians, pharmacy staff, and electronic prescribing representatives in 2023. Initially, three in-depth interviews were conducted to develop the interview questions, resulting in three separate interview guides for each participant group (supplementary file no.1 ). Participants were purposively selected, including 12 physicians, 15 electronic prescribing representatives, and 9 pharmacy staff members. Interviews continued until data saturation was reached. The interviews were recorded, transcribed, and analyzed using content analysis with MAXQDA version 10 software. To identify challenges, sessions were held, and a final list of challenges was categorized. In the final stage, expert panels were formed to propose solutions.
Result
The challenges identified in this study were categorized into two main domains: "Organizational Challenges" and "Systemic Challenges." Organizational challenges included issues related to insurance (16 cases), patient referrals (4 cases), stakeholder education and communication (6 cases), and supervision (8 cases). Systemic challenges included infrastructure problems (18 cases), user interface (UI) issues (14 cases), and database issues (10 cases). The primary challenges in implementing electronic prescribing were system downtime and sluggishness, internet connectivity issues, and the existence of multiple insurance systems. Expert panel discussions resulted in proposed solutions, including the uniform design of software by the Ministry of Health, the establishment of an integrated electronic referral system, conducting practical training sessions for physicians, and implementing electronic signatures.
Conclusion
Electronic prescribing in Iran is still in its early stages and will inevitably face challenges and problems. Continuous monitoring of electronic prescribing systems is essential to address implementation issues promptly. Overall, improvements in infrastructure, integration of insurance systems, implementation of electronic signatures, adherence to electronic prescribing standards, and provision of practical training are recommended.
Development and in vitro/in vivo evaluation of taste-masked orodispersible films of dapoxetine hydrochloride using ion exchange resins
Authors: Zhou Ying , Yan Peng , Zhao Xiangcheng , Zhang Hailong , Yang Yan , Ding Jinsong 
Published: September 2024

Abstract

Dapoxetine hydrochloride tablets are the most commonly used drug for the treatment of premature ejaculation (PE). However, there exists a limitation about medication with water, thereby decreasing patient compliance. This study aimed to develop taste-masked orodispersible films (ODFs) of dapoxetine hydrochloride using ion exchange resins. It was found that the based-Kyron T-134 resin complex achieved a high drug loading rate of 75.9 ± 1.4%, establishing the mass ratio of dapoxetine hydrochloride to Kyron T-134 at 2:1, and adjusting the solution pH to 5.4 ± 0.05. The effect of pH on the drug loading of the resin was initially characterized by SEM, while the binding mechanism between dapoxetine hydrochloride and the resin was investigated by XRD, DSC, and FTIR. The ODF exhibited favorable mechanical properties and palatability. Meanwhile, the drug release could reach 100.8% of the drug over 15 minutes in a simulated gastric environment medium. Furthermore, pharmacokinetic studies conducted in healthy volunteers demonstrated that the ODF was bioequivalent to commercially available tablets Priligy®. Therefore, this ODF, characterized by its pleasant taste and water-free administration, offers a novel and convenient oral formulation for patients with PE, thereby enhancing patient compliance.
It was like I was in my own world: -- a qualitative inquiry of patients using virtual reality to mitigate cancer pain
Authors: Groninger Hunter , Ali Nadia , Gomes Kylie , Violanti Diana 
Published: September 2024

Abstract

Background: Virtual reality (VR) is a rapidly evolving technology that has been shown to improve pain severity in different disease states, including cancer. To date, VR pain studies have used off-the-shelf products for pain distraction. What are user preferences for VR content to mitigate cancer pain?
Objective: Through qualitative inquiry, to explore and understand user preferences for VR distraction therapies to mitigate cancer-related pain.
Methods: We conducted semi-structured interviews of 12 patients participating in a VR cancer pain therapy clinical trial. Using a grounded theory approach, emerging themes and subthemes were analyzed to elucidate patient experiences and preferences for VR content.
Results: Participants described distinct themes related to VR use, specifically experiences of immersion, distraction, relaxation, and safety. Higher experience of immersion and distraction were associated with improvement in cancer pain severity. Some participants had to adapt to VR technology to use it successfully. Regarding future VR content development, participants voiced preferences for content related to home, childhood, natural environments, and family and friends.
Conclusion: Patients associate higher levels of virtual immersion and familiar, natural virtual experiences with successful VR distraction therapy for cancer pain analgesia.