bluuebunny/crossref_metadata_2025_split huggingface dataset:
320-Row Multidetector CT Angiography in the Detection of Critical Cerebrovascular Anomalies
Authors: Hébert Julien , Roncarolo Federico , Tampieri Donatella , Cortes Maria delPilar 
Published: March 2016

AbstractBackground: The acquisition of a new 320-row multidetector computed tomography angiography (CTA) scanner at the Montreal Neurological Institute and Hospital has provided higher quality imaging with less radiation exposure and shorter time of acquisition. However, its reliability has not been fully proven in critical vascular lesions when it comes to replacing a more invasive examination such as cerebral angiography. We wished to validate the accuracy of this equipment to investigate four common indications for patients to undergo conventional digital subtraction angiography: subarachnoid hemorrhage, vasospasm, unusual intracerebral hemorrhage, and unruptured aneurysm. Methods: Radiological reports and relevant imaging from 82 consecutive subjects who underwent a 320-row multidetector CTA followed by cerebral angiography from February 2010 to February 2014 were retrospectively analysed. A total of 102 cerebrovascular anomalies were found. Reports from both imaging modalities were compared to determine the diagnostic accuracy of CTA. Results: The overall sensitivity and specificity of 320-row multidetector CTA for detecting cerebrovascular abnormalities were, respectively, 97.60% and 63.20%. Similar results were obtained for all four categories of clinical indications. Conclusion: Results obtained from CTA were consistent with those obtained on digital subtraction angiography regardless of the vascular pathology. To our knowledge, this study is the first validating the accuracy of 320-row CTA in diagnosing critical cerebrovascular lesions.
The Arab-Israeli Conflict Simulation Game
Authors: Taylor Edgar 
Published: March 2016

The popular undergraduate political science course on “The Arab-Israeli Conflict” at the University of Michigan has had as its focus since 1975 an enormously successful large-scale simulation game, or simprovisation in Frederick Goodman’s phrase. While the four-credit upper division level course of some 100 students is of the quite standard lecture-discussion section format, the simulation game has been closely integrated into it. The game is the goal towards which the students move and is the educational structure around which the course has been organized.The concept of simulation gaming was introduced almost as an aside when Clement Henry and I were designing the course, to be taught by Professor Henry, in 1974. The games organized that year were small, short and disjointed, but they were sufficient to demonstrate the educational utility of the idea, if nothing else. The following year, with the central collaboration of Leonard Suranski, the game was moved to the fore and from that point on it has been the focus of the course.
Manuscript Libraries in Istanbul
Authors: Kut Günay 
Published: March 2016

Manuscript libraries, the items collected in them, their location, and something of their history can be classified as follows (previous work on this subject was described in Lütfü Eroğiu’s “Istanbul Kütüphaneleri”):
1.Ministry of Culture and Tourism’s libraries under the auspices of the General Directorate of Libraries.2.Ministry of Culture and Tourism’s libraries under the auspices of the General Directorate of Monuments and Museums.3.University libraries.4.Public libraries.5.Libraries under the auspices of the General Directorate of Foundations.6.Private libraries, such as those associated with banks or newspapers.
Current Bibliographical Work: The Middle East
Authors: Albin Michael W. 
Published: March 2016

My Purpose in this brief presentation is to offer a summary of developments in the field of Middle Eastern and Islamic bibliographic studies. Examples (and they are only examples of what is a widespread recognition of the importance of bibliography in the scholarly enterprise) are drawn from various fields of activity, from the immense Library of Congress to the efforts of a lone bibliographer at her PC in Denver. I have also tried to give an international flavor with an example of the important work being done in Istanbul. I have appended the names and addresses of the bibliographic projects to which I refer in this presentation.The jewel in the crown, so to speak, of the bibliographic effort of the Library of Congress is the Near East National Union List, a catalogue of Arabic, Persian, and Turkish language books and serials in libraries in the United States and Canada.
The Present Situation of Islamic and Middle Eastern Studies in Korea (South)
Authors: Rew Joung Yole 
Published: March 2016

Although the first contact between Korea and the Middle East dates back to the ninth or twelfth century, academic interests in Islamic and Middle Eastern Studies began in 1965 with the establishment of the Department of Arabic Language and Literature at the Hankuk University of Foreign Studies in Seoul.The birth of the Third Republic of Korea in 1961 signaled a new diplomatic move into the non-aligned world, particularly the Arab Middle East as it gained in importance in the international political and economic community. At the same time, the Korean economy began to expand and her trade found markets in the Middle East. These developments are some of the important factors which gave birth to the Department of Arabic Language and Literature.
Some Recent Thinking on Slavery in Islamic Africa and the Middle East
Authors: Philips John Edward 
Published: March 2016

Slavery and its effects will probably long remain among the most contentious of topics. Outlawed universally only recently, the institution is one of humanity’s oldest and most widespread forms of domination. It still exists, despite laws to the contrary, in some societies around the world. Social disabilities suffered by former slaves and their descendants are important legacies. And the lessons which the history of slavery can teach us have still not been fully elucidated or absorbed. It thus remains a topic of importance to teachers and researchers in every branch of humanities and social science.The literature on slavery has been dominated by the study of plantation slavery in the Western world, especially the Caribbean, Brazil and the United States. Studies of slavery in other areas and times have often been colored by biases and preconceptions based on American chattel slavery. Even when the intent of a scholar has been to contrast slavery in other societies with that in the Americas, the questions posed and the methods used have too often been shaped by the questions and methods of scholars working in the Americas. This has vitiated attempts at comparison.
Middle East Studies On-Line
Authors: Anderson Jon W. 
Published: March 2016

Materials of Middle East studies and not just for Middle East studies are increasingly appearing on-line. The ‘Net (Internet) that brought file archives, newsgroups and mailing lists devoted to regional issues and material has become a publishing medium in the Web (World Wide Web) with more and more of the output of Middle East studies themselves. The Bulletin now has a site, or “homepage,” on the World Wide Web at http://www.cua.edu/www/mesabul with select articles from recent issues and connections to material on the MESA Bulletin Gopher.The World Wide Web has been the breakthrough technology for making the Internet user-friendly and mainstream. WWW hides the “computery” aspects of the Internet behind snappy graphics and an easy-to-use interface that together have fostered much recent press and commercial enthusiasm over “the Net,” such as:
It’s similar to what the library was 100 years ago, or the telegraph. It will be bigger and better than television. We’re not talking about a 500-channel medium. We’re talking about 250,000 channels that speak across all borders It represents who we are, how we act, transact business and engage in relationships. The Internet is about information empowerment. I think it will change world culture. (Michael Wolff in Investor’s Business Daily 21 Sep 95, p. A8)This summer, the number of commercial Internet sites passed those of educational institutions. The Internet, in a sense, has graduated.
For a “Foreign” Audience: The Challenges of Teaching Arabic Literature in the American Academy
Authors: Al-Nowaihi Magda M. 
Published: March 2016

Recently Mary Louise Pratt suggested that we expunge the term ‘foreign’ as it applies to non-European languages and literature, and that we replace it with the term ‘modern,’ thereby “put[ting] an end to another lexical legacy of the Cold War.” I want to argue that, at least for the time being, replacing the term ‘foreign’ would be a dangerous masking, a denial of the realities of the encounters that, from my vantage point as an Arab and a professor of Arabic literature in the American academy, are still characterized by power inequalities, ignorance, and outright racism and hostility, encounters with ‘foreignness’ that must, at the very least, be apprehended as such.Arabic literature is primarily taught in this country in departments of Middle or Near Eastern Studies. Almost everyone in the humanities today is aware of how institutional structures of limited funding and resources, the distinctions between tenured, non-tenured, and adjunct faculty, the politics of publication and advancement, and so on affect the production of the knowledge that our students and readers are exposed to. In the case of Area Studies departments the problems are more acute. It is not simply that the resources are less, the support from the administration weaker, and the prestige at the bottom of the academic food chain, all of which are true. It is also that, when it comes to Area Studies, it becomes almost impossible for the American academy to be an arena of opposition and contestation. Edward Said traced the history of Area Studies departments in Orientalism over twenty years ago, and exposed the ways in which the knowledge they produce has served the interests of some at the expense of others, and has functioned to consolidate a world order, ‘new’ or ‘old’ does not seem to make much difference, of a privileged few, and a disenfranchised majority.
Shedding Some Light on Contemporary Musicians in Palestine
Authors: El-Ghadban Yara 
Published: March 2016

I talked to my wife in Ram Allah a few hours ago, and I was wondering why I should continue playing music,…but then I realized that this instrument can be a weapon too.With those Words, Samir Joubran plucked the first note on his ‘ud. His comments are echoed by many of his Palestinian peers, who seize every opportunity to bring awareness to Palestinian suffering through their music. His first solo improvisation or taqsim immediately set the mood for a truly captivating evening of music and song, ranging from classical instrumental to nationalist to Arab folk and Palestinian repertoire. His performance was one of a series of events that took place in mid-October 2000, in Montreal, Canada, as part of “Rhythms from Palestine,” a cultural event organized by MAP, or Medical Aid for Palestine, a non-profit organization based in Montreal.
How Social Innovation ‘Came to Be’: Tracing the Evolution of a Contested Concept
Authors: AYOB NOORSEHA , TEASDALE SIMON , FAGAN KYLIE 
Published: March 2016

AbstractSocial innovation is a contested concept with multiple meanings that have implications beyond academia. It is not a new term – its sociological heritage can be dated to the late nineteenth century. However, until the twenty-first century the concept was sparsely utilised, and, despite its current popularity among policy makers in Europe and the United States, remains largely ignored by social policy researchers. Through bibliometric analysis we identify the most influential articles on social innovation and explore how these have conceptualised the term. We show that over time social innovation has taken on a set of meanings far removed from its sociological roots. In particular we identify a weak tradition that sees social innovation as any increase in aggregate individual utility arising from an innovation, and a strong tradition that focuses on the process of collaboration between different groups and the restructuring of power relations. We conclude by outlining implications for social policy research.
Global Animal Law: What It Is and Why We Need It
Authors: Peters Anne 
Published: March 2016

AbstractThe symposium collection in this issue ofTEL, consisting of four articles including this framing article, seeks to conceptualize and flesh out a new branch of law and legal research: global animal law. The starting hypothesis is that contemporary animal law must be global or transnational (that is, both transboundary and multilevel) in order to be effective. In times of globalization, all aspects of (commodified) human−animal interactions (from food production and distribution, working animals and uses in research, to breeding and keeping of pets) possess a transboundary dimension. Animal welfare has become a global concern, which requires global regulation. This foreword introduces the three symposium articles, sketches out the research programme of global animal law and links its emergence to the ongoing ‘animal turn’ in the social sciences, including political philosophy.
Screen-printed flexible MRI receive coils
Authors: Corea Joseph R. , Flynn Anita M. , Lechêne Balthazar , Scott Greig , Reed Galen D. , Shin Peter J. , Lustig Michael , Arias Ana C. 
Published: March 2016

AbstractMagnetic resonance imaging is an inherently signal-to-noise-starved technique that limits the spatial resolution, diagnostic image quality and results in typically long acquisition times that are prone to motion artefacts. This limitation is exacerbated when receive coils have poor fit due to lack of flexibility or need for padding for patient comfort. Here, we report a new approach that uses printing for fabricating receive coils. Our approach enables highly flexible, extremely lightweight conforming devices. We show that these devices exhibit similar to higher signal-to-noise ratio than conventional ones, in clinical scenarios when coils could be displaced more than 18 mm away from the body. In addition, we provide detailed material properties and components performance analysis. Prototype arrays are incorporated within infant blankets for in vivo studies. This work presents the first fully functional, printed coils for 1.5- and 3-T clinical scanners.
Intracellular nanoparticles mass quantification by near-edge absorption soft X-ray nanotomography
Authors: Conesa Jose Javier , Otón Joaquín , Chiappi Michele , Carazo Jose María , Pereiro Eva , Chichón Francisco Javier , Carrascosa José L. 
Published: March 2016

AbstractWe used soft X-ray three-dimensional imaging to quantify the mass of superparamagnetic iron oxide nanoparticles (SPION) within whole cells, by exploiting the iron oxide differential absorption contrast. Near-edge absorption soft X-ray nanotomography (NEASXT) combines whole-cell 3D structure determination at 50 nm resolution, with 3D elemental mapping and high throughput. We detected three-dimensional distribution of SPIONs within cells with 0.3 g/cm3 sensitivity, sufficient for detecting the density corresponding to a single nanoparticle.
DBS-platform for biomonitoring and toxicokinetics of toxicants: proof of concept using LC-MS/MS analysis of fipronil and its metabolites in blood
Authors: Raju Kanumuri Siva Rama , Taneja Isha , Rashid Mamunur , Sonkar Ashish Kumar , Wahajuddin Muhammad , Singh Sheelendra Pratap 
Published: March 2016

AbstractA simple, sensitive and high throughput LC-MS/MS method was developed and validated for quantification of fipronil, fipronil sulfone and fipronil desulfinyl in rat and human dried blood spots (DBS). DBS samples were prepared by spiking 10 μl blood on DMPK-C cards followed by drying at room temperature. The whole blood spots were then punched from the card and extracted using acetonitrile. The total chromatographic run time of the method was only 2 min. The lower limit of quantification of the method was 0.1 ng/ml for all the analytes. The method was successfully applied to determine fipronil desulfinyl in DBS samples obtained from its toxicokinetic study in rats following intravenous dose (1 mg/kg). In conclusion, the proposed DBS methodology has significant potential in toxicokinetics and biomonitoring studies of environmental toxicants. This microvolume DBS technique will be an ideal tool for biomonitoring studies, particularly in paediatric population. Small volume requirements, minimally invasive blood sampling method, easier storage and shipping procedure make DBS a suitable technique for such studies. Further, DBS technique contributes towards the principles of 3Rs resulting in significant reduction in the number of rodents used and refinement in sample collection for toxicokinetic studies.
Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms
Authors: Asai Takashi , Hatlen Megan A. , Lossos Chen , Ndiaye-Lobry Delphine , Deblasio Anthony , Murata Kazunori , Fleisher Martin , Cortizas Elena M. , Verdun Ramiro E. , Petrini John , Nimer Stephen D. 
Published: March 2016

AbstractMultiple myeloma is a plasma cell neoplasm with an extremely variable clinical course. Animal models are needed to better understand its pathophysiology and for preclinical testing of potential therapeutic agents. Hematopoietic cells expressing the hypermorphic Rad50s allele show hematopoietic failure, which can be mitigated by the lack of a transcription factor, Mef/Elf4. However, we find that 70% of Mef−/−Rad50s/s mice die from multiple myeloma or other plasma cell neoplasms. These mice initially show an abnormal plasma cell proliferation and monoclonal protein production, and then develop anemia and a decreased bone mineral density. Tumor cells can be serially transplanted and according to array CGH and whole exome sequencing, the pathogenesis of plasma cell neoplasms in these mice is not linked to activation of a specific oncogene, or inactivation of a specific tumor suppressor. This model recapitulates the systemic manifestations of human plasma cell neoplasms, and implicates cooperativity between the Rad50s and Mef/Elf4 pathways in initiating myelomagenic mutations that promote plasma cell transformation.
Comparing the defence-related gene expression changes upon root-knot nematode attack in susceptible versus resistant cultivars of rice
Authors: Kumari Chanchal , Dutta Tushar K. , Banakar Prakash , Rao Uma 
Published: March 2016

AbstractRice is one of the major staple food crops in the world and an excellent model system for studying monocotyledonous plants. Diseases caused by nematodes in rice are well documented and among them, root-knot nematode (RKN), Meloidogyne graminicola, causes extensive yield decline. It is therefore necessary to identify novel sources of natural resistance to RKN in rice and to investigate the rice-RKN interaction in detail to understand the basal plant defence mechanisms and nematode manipulation of the host physiology. To this end, six different cultivars of rice were initially screened for RKN infection and development; Pusa 1121 and Vandana were found to be most susceptible and resistant to RKN infection, respectively. In order to investigate the role of major hormone-regulated plant defence pathways in compatible/incompatible rice-RKN interaction, some well-identified marker genes involved in salicylate/jasmonate/ethylene pathway were evaluated for their differential expression through qRT-PCR. In general, our study shows a remarkable discrepancy in the expression pattern of those genes between compatible and incompatible rice-RKN interaction. As most information on the molecular interplay between plants and nematodes were generated on dicotyledonous plants, the current study will strengthen our basic understanding of plant-nematode interaction in the monocot crops, which will aid in defining future strategies for best plant health measures.
Illumina microRNA profiles reveal the involvement of miR397a in Citrus adaptation to long-term boron toxicity via modulating secondary cell-wall biosynthesis
Authors: Huang Jing-Hao , Qi Yi-Ping , Wen Shou-Xing , Guo Peng , Chen Xiao-Min , Chen Li-Song 
Published: March 2016

AbstractThe mechanisms underlying tolerance to B-toxicity in plants are still controversial. Our previous studies indicated that B-toxicity is mainly limited to leaves in Citrus and that alternations of cell-wall structure in vascular bundles are involved in tolerance to B-toxicity. Here, miRNAs and their expression patterns were first identified in B-treated Citrus sinensis (tolerant) and C. grandis (intolerant) leaves via high-throughput sequencing. Candidate miRNAs were then verified with molecular and anatomical approaches. The results showed that 51 miRNAs in C. grandis and 20 miRNAs in C. sinensis were differentially expressed after B-toxic treatment. MiR395a and miR397a were the most significantly up-regulated miRNAs in B-toxic C. grandis leaves, but both were down-regulated in B-toxic C. sinensis leaves. Four auxin response factor genes and two laccase (LAC) genes were confirmed through 5′-RACE to be real targets of miR160a and miR397a, respectively. Up-regulation of LAC4 resulted in secondary deposition of cell-wall polysaccharides in vessel elements of C. sinensis, whereas down-regulation of both LAC17 and LAC4, led to poorly developed vessel elements in C. grandis. Our findings demonstrated that miR397a plays a pivotal role in woody Citrus tolerance to B-toxicity by targeting LAC17 and LAC4, both of which are responsible for secondary cell-wall synthesis.
Tunable high-order sideband spectra generation using a photonic molecule optomechanical system
Authors: Cao Cong , Mi Si-Chen , Gao Yong-Pan , He Ling-Yan , Yang Daquan , Wang Tie-Jun , Zhang Ru , Wang Chuan 
Published: March 2016

AbstractA tunable high-order sideband spectra generation scheme is presented by using a photonic molecule optomechanical system coupled to a waveguide beyond the perturbation regime. The system is coherently driven by a two-tone laser consisting of a continuous-wave control field and a pulsed driving field which propagates through the waveguide. The frequency spectral feature of the output field is analyzed via numerical simulations, and we confirm that under the condition of intense and nanosecond pulse driving, the output spectrum exhibits the properties of high-order sideband frequency spectra. In the experimentally available parameter range, the output spectrum can be efficiently tuned by the system parameters, including the power of the driving pulse and the coupling rate between the cavities. In addition, analysis of the carrier-envelop phase-dependent effect of high-order sideband generation indicates that the system may present dependence upon the phase of the pulse. This may provide a further insight of the properties of cavity optomechanics in the nonlinear and non-perturbative regime, and may have potential applications in optical frequency comb and communication based on the optomechanical platform.