bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of the quality of audit firms peer-review on tax evasion
Authors: Taha Hazem 
Published: December 2017

This study examines the quality of audit firms peer-review impact on the audit activity on firms to disclose fair financial reports which will influences tax revenue of the countries and to reduce the Tax evasion. Audit Firms peer-review play a significant role in the countries tax evasion. The Audit Firms peer-review ensure that different investors and business in nations are confident and knowledgeable when making business decisions. The AICPA Peer Review is committed to improving the quality of auditing and accounting services.Â The program is a universal assessment whose value in serving the interest public and companies lies in its remedial and educational nature.Â Audit Firms peer-review has an impact on the collection of revenue considering the tests, there is an importance in the association between tax collected after auditing and before auditing. This demonstrates that there is increase in revenue collection after quality audit.Â
The Use of Flashcards in Improving Vocabulary Mastery of Students with Disability
Authors: Habibi Nugroho 
Published: December 2017

This research comes from the weakness of vocabulary mastery of students with disability. This researcher used Classroom Action Research (CAR) in integrated classroom to improve vocabulary of the students with disability at the second grade of SMP Diponegoro, Junrejo, Batu in the academic year 2017/2018 by using flashcards. In this research, the researcher becomes a teacher while the English teacher becomes a volunteer or therapist to help, control and manage the class. The result of the study showed that before the implementation of flashcards, all students with disability’ score were under 75, with the lowest score was 50 and the highest score was 70. From six students with disability, no one passed Standard Minimum Criteria (KKM). Therefore, in the cycle 1, all students with disability passed Standard Minimum Criteria (KKM). The lowest score was 80 and the highest score was 100.[Penelitian ini berasal dari kelemahan kosakata siswa berkebutuhan khusus. Peneliti ini menggunakan Penelitian Tindakan Kelas (PTK) dikelas integrasi untuk meningkatkan kosakata siswa berkebutuhan khusus dikelas dua SMP Diponegoro, Junrejo, Batu tahun ajaran 2017/2018 dengan menggunanakan flashcards. Dalam penelitian ini, peneliti berperan menjadi guru sementara itu guru bahasa Inggris menjadi relawan atau terapi untuk membantu, mengontrol dan mengatur kelas. Hasil dari penelitian ini menunjukkan bahwa sebelum implementasi flashcrads, nilai seluruh siswa berkebutuhan kusus dibawah 75, dengan nilai terrendah adalah 50 dan nilai tertinggi adalah 70. Dari enam siswa berkebutuhan khussu, tidak siswa ada yang melewati Kriteria ketuntatas minimal (KKM). Oleh karena itu, pada siklus 1, semua siswa berkebutuhan khusus melewati kriteria ketuntasan minimal (KKM). Dengan nilai terrendah 80 dan nilai tertinggi adalah 100.]
Curcumin induce DNA damage and apoptosis through generation of reactive oxygen species and reducing mitochondrial membrane potential in melanoma cancer cells
Authors: Kocyigit Abdurrahim , Guler Eray Metin 
Published: December 2017

Melanoma is the most malignant skin cancer. Curcumin has shown to have therapeutic effects when used in the treatment of malignant diseases. However, the precise molecular mechanisms of its action are not fully elucidated. In this research, we hypothesized that reactive oxygen species (ROS) play a key role in curcumin induced DNA damage, apoptosis and cell dead. To test our hypothesis, cytotoxic, genotoxic, apoptotic, ROS generating and mitochondrial membrane potential (MMP) of curcumin on mouse melanoma cancer cells (B16-F10) and fibroblastic normal cells (L-929) were investigated. Our results demonstrated that curcumin decreased cell viability and MMP and, increased DNA damage, apoptosis and ROS levels in both melanoma cancer and normal cells in a dose dependent manner and, these activities were significantly higher in melanoma cells than in normal cells with higher concentrations. There were positive strong relationships between DNA damage, apoptosis, cytotoxicity and ROS generation and MMP levels in curcumin treated melanoma and normal cells. In summary, this in vitro study provide clear evidence that curcumin induced DNA damage, apoptosis and cytotoxicity via its pro-oxidant activity in a dose dependent manner in both cancer and normal cells and these activities were higher in cancer cells than those of normal cells.
Promoter motifs required for c-mpl gene expression induced by thrombopoietin in CMK cells
Authors: Sunohara Masataka , Sato Iwao , Morikawa Shigeru 
Published: December 2017

Thrombopoietin (TPO) and its receptor, c-Mpl, are the central regulators of megakaryocyte development and platelet production and are also crucial to regulate megakaryocytopoiesis. TPO remarkably elevated c-mpl promoter activity, while the protein kinase C (PKC) inhibitors, GF109203, H7 and Calphostin C, clearly reduced the steady level of its promoter activity. In the present study, motifs crucial for c-mpl promoter activity induced by TPO treatment has been analyzed using a human megakaryoblastic cell line, CMK. Destruction of the –107Sp1 and the –57Sp1 sites in the c-mpl promoter enhancer region resulted in decrease of the promoter activity by 53.1% and 64.4%, respectively, and destruction of –69Ets and –28Ets elements dramatically decreased the promoter activity by 96.4% and 87.8%, respectively, while mutation of –77GATA moderately reduced the activity by 31.4%. The result was in agreement with our previous report that showed the crucial motifs in the c-mpl promoter for the promoter activity induced by PMA-treatment. This indicates that TPO-induced activation of the c-mpl promoter activity is fully modulated by transcription through a PKC-dependent pathway and the two Sp1 and two Ets motifs are crucial for the activation of the c-mpl promoter activity rather than a GATA motif in the c-mpl promoter of CMK cells.
Investigation of role of vascular endothelial growth factor, Annexin A5 and Apelin by immunohistochemistry method in placenta of preeclampsia patients
Authors: Colcimen Nese , Bulut Gülay , Ergul Erkec Ozlem , Ragbetli Murat Cetin 
Published: December 2017

Preeclampsia is a disease characterized by hypertension and proteinuria occurred after 20 weeks of gestation. Preeclampsia is a major cause of maternal and fetal morbidity and mortality. The pathophysiological mechanism of preeclampsia is not known exactly yet. Preeclampsia endothelial cell dysfunction, associated with inadequate trophoblastic invasion is characterized by abnormal placentation. Vascular endothelial growth factor (VEGF) according to is an angiogenic cytokine, Annexin A5 is among endogenous peptides are both expressed from placental trophoblasts and Apelin is a multifunctional peptide and expressed by placental trophoblasts and endothelial cells. It was aimed to investigate roles of these parameters occurring in preeclampsia and to compare immunoreactivity of them in normal and preeclamptic placenta. In this study, placentas were collected from 20 normotensive pregnant women as controls, 16 mild-preeclamptic pregnant women, and 16 severe preeclamptic women. VEGF, Annexin A5 and Apelin were examined in samples of placenta tissues by streptavidin-biotin-peroxidase complex immunohistochemical methods. Immunoreactivity scores (IRS) were obtained for each parameter. VEGF and Apelin IRS were increased significantly in preeclamptic groups compared with control group (p <0.026, p<0.002 respectively). But Annexin A5 IRS was decreased significantly in preeclamptic groups compared with control group (p<0.04). In correlation with the intensity of disease, increase in VEGF and Apelin, and decrease in Annexin A5 supports roles of hemo-dynamic alterations in fetoplacental circulation and structural alterations in uteroplacental bed occurring in preeclampsia.
The in Vitro and in Vivo Anti-Cancer Potential of Mycobacterium Cell Wall Fraction (MCWF) Against Canine Transitional Cell Carcinoma of the Urinary Bladder
Authors: Filion C Mario , Rodrigues Lucas , Johannes Chad , Masic Aleksandar 
Published: December 2017

Abstract
Transitional cell carcinoma (TCC), is the most common form of urinary bladder cancer in dogs and represents 2% of all reported canine cancers. Canine TCC is usually a high-grade invasive cancer and problems associated with TCC include urinary tract obstruction and distant metastases in more than 50% of affected dogs. TCC is most commonly located in the trigone region of the bladder precluding complete surgical resection. Current treatment options for TCC in dogs include medical therapy, surgery or radiation. Mycobacterium Cell Wall Fraction (MCWF) is a biological immunomodulator derived from non-pathogenic Mycobacterium phlei. MCWF possesses a potential in multiple veterinary areas such as anticancer therapy, palliative care and treatment of infectious diseases in both small and large animals. MCWF is considered a bifunctional anti-cancer agent that induces apoptosis of cancer cells and stimulates cytokine and chemokines synthesis by cells of the immune system. Here we report the results from in vitro and in vivo studies that could suggest use of MCWF as an additional treatment option for TCC in dogs. Particularly, we demonstrated that MCWF induces a concentration dependent inhibition of proliferation of K9TCC cells which was associated with the induction of apoptosis as measured by the proteolytic activation of caspase-3 and the degradation of PARP. Furthermore, we demonstrated the safety and potential for in vivo MCWF treatment efficacy in dogs bearing stage T2 TCC by reducing clinical signs, and improving the quality of life in dogs with TCC.
The impact of water on the ambivalent behavior and paradoxical phenomenon of the amyloid-β fibril protein
Authors: Vajda Tamás , Perczel András 
Published: December 2017

AbstractThe crucial role of water in amyloid-β(Aβ) fibril proteins is evaluated in several ways including the water’s thermodynamic and kinetic solvation effects. As regards the water’s character, its hindered-rotation barriers are also considered. The following protein molecules considered here are: the Aβ40 (PDB ID: 2LMN), Aβ42 (PDB ID: 5KK3 and 2NAO) and the double-layered Aβ17−42 fibril. We discuss: (i) extracellular Aβ40 and Aβ42 fibril monomers exhibit an ambivalent propensity to transform into a helical form toward the N-term region and a β-strand-like form near the C-terminal; (ii) interfacial water molecules play a crucial role in protein-protein interactions, as molecular dynamics simulations have shown a significant impact on the protein-protein binding; (iii) it is shown that the spontaneous dimerization process of the Aβ42 fibril protein in water occurs via a two-step nucleation-accommodation mechanism; (iv) MD simulations of the double-layered Aβ17−42 fibril model show that the C↔C interface appears more energetically favorable than the N↔N interface due to large hydrophobic contacts; (v) the water’s role in the HET-s prion and in the Aβ fibrillar aggregates; (vi) it was found that the monomer-oligomer equilibrium spontaneously dissociates into stable monomeric species when they are incubated up to 3 μm for a longer time (>1 week) in a physiological buffer.
LTSD and GDMD features for Telephone Speech Endpoint Detection
Authors: Ouzounov Atanas 
Published: December 2017

AbstractThis paper proposes a new contour-based speech endpoint detector which combines the log-Group Delay Mean-Delta (log-GDMD) feature, an adaptive twothreshold scheme and an eight-state automaton. The adaptive thresholds scheme uses two pairs of thresholds - for the starting and for the ending points, respectively. Each pair of thresholds is calculated by using the contour characteristics in the corresponded region of the utterance. The experimental results have shown that the proposed detector demonstrates better performance compared to the Long-Term Spectral Divergence (LTSD) one in terms of endpoint accuracy. Additional fixed-text speaker verification tests with short phrases of telephone speech based on the Dynamic Time Warping (DTW) and left-to-right Hidden Markov Model (HMM) frameworks confirm the improvements of the verification rate due to the better endpoint accuracy.
A Survey on Key(s) and Keyless Image Encryption Techniques
Authors: Ranjan Kumar H. S. , Fathimath Safeeriya S. P. , Aithal Ganesh , Shetty Surendra 
Published: December 2017

AbstractAs in recent years digital data transmission and image application have been increasing, maintaining secure transmission of image is of high importance. Image Encryption is implemented to achieve security on image applications. This paper exhibits a survey on various existing image encryption techniques. The paper mainly focuses on two types: Image encryption with Key(s) and Image Encryption without Key(s). In addition it also describes several properties of a good image encryption technique. The paper presents a survey of most popular algorithms and research papers that are related with different image encryption techniques.
Operational Modal Analysis of the Cablestayed Footbridge
Authors: Kortiš Ján , Daniel Ľuboš , Farbák Matúš , Maliar Lukáš , Škarupa Milan 
Published: December 2017

Abstract
Modern architecture leads to design subtle bridge structures that are more sensitive to increased dynamic loading than the massive ones. This phenomenon can be especially observed on lightweight steel structures such as suspended footbridges. As a result, it is necessary to know precisely its dynamic characteristics, such as natural frequencies, natural shapes and damping of construction. This information can be used for further analysis such as damage detection, system identification, health monitoring, etc. or also for the design of new types of construction. For this purpose, classical modal analysis using trigger load or harmonic vibration exciter in combination with acceleration sensors is used in practice. However, there are many situations where it is not possible to stop the traffic or operation of the bridge. The article presents an experimental measurement of the dynamic parameters of the structure at the operating load using the operational modal analysis.
Experimental Investigation of the Vehicle–Ground Interaction – Experiment Preparation and Preliminary Results
Authors: Valašková Veronika , Vlček Jozef 
Published: December 2017

Abstract
Interaction of the moving vehicle and the ground represents the actual engineering, environmental and economic problem. Due to the complexity of the problem, a combination of the experimental measurement and the computational simulation to understand the interaction mechanism is the most beneficial approach. Results of the in-situ observation serve as an input for the numerical analysis and also as a background for the calibration of the model. Presented paper brings the summary of the experiment preparation and preliminary results which are necessary for further analyses and numerical models. Computational simulations will be helpful for understanding the vehicle-ground interaction when inputs will be verified by the experimental way at known boundary conditions.
Routine Testing of Bitumen Binders
Authors: Holý Michal , Remišová Eva 
Published: December 2017

AbstractThe quality of bituminous binders used in the construction and maintenance of road surfaces is currently assessed by empirical testing based on obtaining one value for specific boundary conditions, which were designed about 100 years ago. Basic empirical tests include the softening point and penetration, but the practice shows that these tests appear to be inadequate. The evaluation of changes of bitumen properties during the production and paving process of bituminous mixture is also important. The paper points out how the “traditional” tests as softening point and penetration and viscosity are sufficient to evaluate properties of bitumen binders.
Modelling of Railway Track Temperature Regime with Real Heat-Technical Values for Different Climatic Characteristics
Authors: Hodás Stanislav , Pultznerová Alžbeta 
Published: December 2017

AbstractHigh quality of railway track construction is a major priority. One of the quality elements is the resistance to load of railway formation with individual structural layers caused by negative temperatures during the critical freezing period of winter. Numerical modelling allows obtaining more control outputs at different climatic loads. The presented paper shows the load of railway track model with different variants of climate and shows the importance in the designing of the non-transport load under negative temperatures, i.e. observation of transition of the zero isotherm through the layers of railway subgrade. If the subgrade layers of the railway formation are built with high quality and durability then the axis of the track will keep its geometric spatial position during the long-time operation.
Airport Planning and Design – Legal and Professional Competence Requirements
Authors: Kazda Antonin 
Published: December 2017

Abstract
Airport design and planning considerably differs from the design of other transport infrastructure. The reasons are the wide scope of regulation in civil aviation and the lack of links between the Civil Aviation Act and the Building Act. The effect is that the sequence of procedures, negotiation, and/or document approval is not clearly defined. The situation is further complicated by the fact that an airport is a unique construction both for the investor and for the local building authority. The paper is an outcome of our research, building on long-term experience in airport planning and design, and the elucidation of planning and approval processes with experts from the Transport Authority and the Ministry of Transport and Construction of the Slovak Republic.
Editorial 2016: Changes for the Future
Authors: Matulić Daniel , Tomljanović Tea , Piria Marina 
Published: December 2017

Abstract
By changing its editorial system, the Croatian Journal of Fisheries continues to move towards a more rigorous review which is slowly but surely strengthening its quality and impact. New editors-in-chief have been elected and a co-operation with De Gruyter Open publishers has been established. The official abbreviation of the Journal – CROAT J FISH – was released and it indicated an important change in the manuscript submission process. Also, this Editorial provides information on the articles published in 2015, as well as a list of reviewers who participated in the review process.
Zooplankton structure in two interconnected ponds: similarities and differences
Authors: Špoljar Maria , Tomljanović Tea , Dražina Tvrtko , Lajtner Jasna , Štulec Helena , Matulić Daniel , Fressl Jelena 
Published: December 2017

Abstract
The research of zooplankton diversity, abundance and trophic structure was conducted during the summer period in pelagial zone on the longitudinal profile of the Sutla River Backwater. Investigated site consists of two interconnected basins: transparent Upper Basin with submerged macrophytes and turbid Lower Basin without macrophytes in the littoral zone. In the Upper Basin, abundance and diversity of zooplankton in the pelagial was higher in comparison to the Lower Basin, with prevailing species of genus Keratella as microfilter-feeder, and genera of Polyartha and Trihocerca as macrofilter-feeder rotifers. On the contrary, in the Lower Basin, crustaceans dominated in abundance. Microfilter-feeder cladoceran (Bosmina longirostris) and larval and adult stages of macrofilter-feeder copepod (Macrocyclops albidus) prevailed in the Lower Basin. Fish predation pressure was more pronounced in the pelagial of the Upper Basin, indicated by low cladoceran abundance in the surface layer. Although the studied basins were interconnected, results indicate significant (Mann-Whitney U test, p < 0.05) differences in the zooplankton structure as a potential result of the macrophyte impact on environmental conditions and fish predation pressure.
Effects of storage conditions on quality characteristics of commercial aquafeeds and growth of African catfish Clarias gariepinus
Authors: Solomon Shola Gabriel , Tiamiyu Lateef Oloyede , Okomoda Victor Tosin , Adaga Kamwan 
Published: December 2017

Abstract
This study was conducted to determine the effect of storage conditions on the quality of feed and the aftermath effect of feeding fish with such feeds. Three commercial diets used for this study included Coppens®, Multifeed® and Vital feed®. Feed was stored either by opening the bag to the atmosphere (WO), the bag opened with neck tied using a rubber ring to prevent exposure to the atmosphere (OT) or sealed (SC) until the start of the feeding trials. The feed was stored under these conditions for six months. Nutrient analyses revealed significant changes in feeds held under the WO condition when compared with other storage conditions. Nutritive changes also varied with commercial feed type. Mould infestation of the feed was noticeable more in the WO condition of storage compared to the SC condition. After feeding C. gariepinus for fifty-six days, lesions were observed on fish fed mouldy feed held under the WO condition, which led to mass mortalities. Growth performance was higher in all fish fed SC stored feed, and for those fed Coppens® and Multifeed® under OT storage conditions. It is advised that storage of fish feeds up to six months should be undertaken with considerable care and attention.
Cannibalism and Performance Evaluation of Hybrids betweenClarias batrachusandClarias gariepinus
Authors: Olufeagba Samuel Olabode , Okomoda Victor Tosin 
Published: December 2017

AbstractCannibalism is an important characteristic of African catfish that significantly reduces the number of stocked fish at harvest. This study evaluates the effect of reciprocal hybridization ofClarias batrachusandClarias gariepinuson cannibalism and growth performance of their progenies in an indoor rearing system. The result obtained reveals excellent performance of hybrids ofC. gariepinus♂ andC. batrachus♀ over the purebreds in terms of growth. However, the reciprocal hybrids betweenC. gariepinus♀ andC. batrachus♂ all died few hours after hatching. Cannibalism was significantly reduced in the crosses betweenC. gariepinus♂ andC. batrachus♀ with 100% survival after five months of culture. Hence, this could be exploited in commercial production of catfish to reduce cannibalism and increase harvest size of fish farmers.
Morphometric Characteristics of CatfishSilurus triostegus(Heckel, 1843) from the Tigris and Shatt Al-Arab Rivers, Iraq
Authors: Jawad Laith A. , Al-Janabi Muhammad I. G. 
Published: December 2017

AbstractThirteen morphometric characters of catfishSilurus triosteguswere studied from three localities on the Tigris and Shatt al-Arab rivers, Iraq. Monthly samples revealed no significant differences between genders. Positive allometric growths for all morphometric characters studied were observed. This study gives information to fishery biologists about morphometric characters ofS. triostegusfrom the Tigris and Shatt al-Arab rivers to assist in planning of conservation strategies for this fish species.