bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous Hallux Valgus Surgery Without Distal Metatarsal Articular Angle Correction
Authors: Crespo Romero Eusebio , Arcas Ordoño Alvaro , Peñuela Candel Raquel , Gómez Gómez Silvia , Arias Arias Angel , Gálvez González Jaime , Crespo Romero Ricardo 
Published: January 2017

Background. Many factors are considered predictors of recurrence after hallux valgus (HV) surgery, including preoperative distal metatarsal articular angle (DMAA). The restoration of the bone and joint alignment would be more important than realigning the cartilaginous surface of the metatarsal head. Therefore, is DMAA correction essential for a good clinical and radiological results after HV surgery? This study aims to illustrate the results of percutaneous forefoot surgery (PFS) for correction of HV deformity without DMAA correction. Material and Methods. A prospective single-center study of 74 patients (89 feet), with mild-to-moderate hallux valgus deformity, who underwent PFS. The mean latest follow-up was 57.3 months. Results. Preoperative median visual analog scale was 7 points and AOFAS scores were 52 points. At the mean latest follow up both scores improved to 0 points and 90 points, respectively. Median HV angle and intermetatarsal angle changed from 30° and 12° preoperatively, to 21° and 11° at mean latest follow-up. Overall, 80% of the patients were satisfied or very satisfied. Recurrence of medial first metatarsal head pain occurred in 12 cases (13.5%). Conclusions. PFS, without DMAA correction, is a valid procedure for surgical correction in patients with HV, despite the slightly worse radiographic results in our study. Levels of Evidence: Level II: Prospective study
Usefulness of Urinoculture to Patients With Dementia and Femoral Neck Fracture at Admission to Hospital
Authors: Garcia-Nuño Laura , Villamil Carlos , González-Cuevas Araceli , Martí David , Capilla Silvia , Vives Maria José , Oncins Xavier , Torner Pere , Castellanos Juan , Font-Vizcarra Lluís 
Published: January 2017

Introduction: While preoperative urinary tract infection (UTI) has the potential to cause bacteremia and postsurgical acute prosthetic joint infections (APJIs), the influence of asymptomatic bacteriuria (AB) in these infections remains unclear. So the majority of guidelines not recommend the treatment of AB prior to the surgery. However, as patients with dementia usually cannot explain the symptoms of dysuria, the differential diagnosis between AB and UTI may be very difficult in this group of patients. The principal aim of the study was to compare the rate of positive urine culture at admission in patients with femoral neck fracture with and without dementia and secondarily try to assess the connection of positive urinoculture and postoperative acute gram-negative PJI. Methods: All patients with a femoral neck fracture underwent a urine culture on hospital admission and were prospectively recorded. Variables such as sex, age, institutionalization, dementia and other comorbidities, PJI rate, and in-hospital death were collected. The results of cultures were retrospectively revised. Patients who received postoperative antibiotics or had been diagnosed with UTI during hospital stay were excluded. Statistical comparisons between patients with and without dementia were performed using SPSS software version 17. Results: A total of 148 patients were included (52 with dementia). The rate of positive urine culture was 32% (n = 16) in patients with dementia and 11.5% in patients without dementia ( P = .003). Of these 16 patients with dementia and positive urine culture, 2 (12.5%) developed an acute gram-negative PJI, whereas there were no cases in the group without dementia ( P = .011). Discussion: The only difference between UTI and AB is the expression of symptoms by the patient. However, as patients with dementia have difficulties to explain UTI symptoms, some UTI may be underdiagnosed. Conclusion: Patients with dementia have a statistically higher rate of presurgical positive urine culture compared with patients without dementia.
Randomized Controlled Trial of Postoperative Sensitivity with Warm and Room Temperature Composite
Authors: Campbell I. , Kang J. , Hyde T.P. 
Published: January 2017

Physical properties of composite improve when it is preheated prior to polymerization. However, postoperative sensitivity may be considered a potential complication. A review of the literature revealed no reported randomized controlled trials (RCTs) of postoperative sensitivity when using preheated composite resin. The objective of the study was to determine if preheating composite leads to changes in postoperative sensitivity in a parallel RCT. In total, 120 eligible, consenting adults were recruited in private dental practice and randomized into 2 groups of 60 patients. One group had room temperature composite restorations placed and the second had composite preheated to 39°C. The primary outcome was sensitivity after 24 h by the visual analog scale (VAS), recorded blind by patients. Secondary outcomes were VAS scores recorded over a month. Blind statistical analysis used the Mann-Whitney U test to compare the 24-h VAS score between groups and repeated-measures analysis of variance to assess the change over time. Potential confounders were tested using regression models. A total of 115 patients completed the trial: 57 in the heated composite group and 58 in the room temperature group. Analysis of 24-h VAS scores found no statistically significant difference between the 2 groups ( P = 0.162). Examining the potential confounders confirmed the nonsignificant difference between heated and room temperature groups on the 24-h VAS score, after controlling teeth type and preoperative pulp test (effect size = 0.173, P = 0.317). Analysis of the secondary outcomes found significant changes (within-subject effect) in VAS scores over the review period ( F statistic = 4.7, P = 0.002) but not a significant (between-subject effect) difference between heated and room temperature groups over time (effect size = 0.102, P = 0.197). There was a significant correlation between preoperative VAS score and postoperative VAS score ( P < 0.001). For the restorations in this study, there was no detectable difference in postoperative VAS score between preheated and room temperature composite. Postoperative sensitivity decreased throughout the first month. Postoperative sensitivity was correlated to preoperative sensitivity (ISRCTN 76727312). Knowledge Transfer Statement: The results of this study can be used by clinicians when considering the advantages and disadvantages of preheated composite. The study found no evidence of any change in postoperative sensitivity when using preheated composite. Since preheated composite has superior physical properties, its use for routine care can be considered good practice.
Toothpaste with Nanosized Trimetaphosphate Reduces Enamel Demineralization
Authors: Souza M.D.B. , Pessan J.P. , Lodi C.S. , Souza J.A.S. , Camargo E.R. , Souza Neto F.N. , Delbem A.C.B. 
Published: January 2017

This double-blind crossover study assessed the effects of a low-fluoride (low-F) dentifrice containing nanosized sodium trimetaphosphate (TMP) on enamel demineralization in situ. Nineteen subjects wore palatal appliances containing 4 blocks of bovine enamel and were randomly assigned to brush their teeth with placebo (without F/TMP), 250-ppm F (250F), 250F plus 0.05% nanosized TMP (250F-TMPnano), and 1,100-ppm F (1,100F) dentifrices during 7 d, under cariogenic challenge. Enamel surface hardness and cross-sectional hardness (ΔKHN [Knoop hardness number]), as well as F, calcium (Ca), and phosphorus (P) concentrations, were determined. Also, biofilm that formed on the blocks was analyzed for F, Ca, P, and insoluble extracellular polysaccharide concentrations. Data were submitted to analysis-of-variance models and Student-Newman-Keuls test ( P < 0.05). The 250F-TMPnano dentifrice promoted the lowest ΔKHN among all groups ( P < 0.001), while the percentage of surface hardness loss was similar to 1,100F. Also, similar F, Ca, and P concentrations in enamel were observed for 1,100F and 250F-TMPnano. In the biofilm, the highest F content was observed for 1,100F; Ca content was similar between 1,100F and 250F-TMPnano; and P content was similar among all groups. Similar extracellular polysaccharide values were observed for 250F-TMPnano and 1,100F ( P < 0.001), ionic activity of CaHPO40, CaF+, and HF0 ( P < 0.05) and degree of saturation of hydroxyapatite and CaF2 ( P < 0.05). It was concluded that the protective effect of 250F-TMPnano dentifrice was similar to a conventional dentifrice for most of the variables studied, having a more pronounced effect on the subsurface lesion when compared with the conventional toothpaste (1,100F). Knowledge Transfer Statement: Although toothpastes containing ≥1,000-ppm fluoride are more effective than low-fluoride formulations against dental caries, their early use can lead to side effects. This has prompted intensive research on alternatives to increase the anticaries effect of low-fluoride toothpastes. The present in situ study demonstrated that the addition of sodium trimetaphosphate nanoparticles to toothpastes containing 250-ppm fluoride significantly enhances the protective effect of this formulation against enamel demineralization to levels comparable to a 1,100-ppm fluoride toothpaste in terms of most of the variables studied. Most important, this formulation promoted the lowest loss of subsurface hardness among all groups, suggesting that caries lesions would take longer to develop under clinical conditions when compared with a conventional (1,100-fluoride) toothpaste.
MiR-142 modulates human pancreatic cancer proliferation and invasion by targeting hypoxia-inducible factor 1 (HIF-1α) in the tumor microenvironments
Authors: Lu Yebin , Ji Niandong , Wei Wei , Sun Weijia , Gong Xuejun , Wang Xitao 
Published: January 2017

ABSTRACT
MicroRNAs regulate most protein-coding genes, including genes important in cancer and other diseases. In this study, we demonstrated that the expression of miR-142 could be significantly suppressed in pancreatic cancer specimens and cell lines compared to their adjacent tissues and normal pancreatic cells. Growth and invasion of PANC-1 and SW1990 cells were attenuated by overexpression of miR-142 in vitro. With the help of bioinformatics analysis, hypoxia-inducible factor 1 (HIF-1α) was identified to be a direct target of miR-142, and a luciferase reporter experiment confirmed this discovery. Overexpression of miR-142 decreases protein expression of HIF-1α. In the hypoxic microenvironment, HIF-1α was up-regulated while miR-142 was down-regulated. The invaded cells significantly increased in the hypoxic microenvironment compared to the normoxic microenvironment. The hypoxia treatment induced cells’ proliferation, and invasion could be inhibited by miR-142 overexpression or HIF-1α inhibition. Moreover, expression of epithelial-mesenchymal transition (EMT) markers, Vimentin, VEGF-C and E-cad, was altered under hypoxia conditions and regulated by miR-142/HIF-1α. Above all, these findings provided insights on the functional mechanism of miR-142, suggesting that the miR-142/HIF-1α axis may interfere with the proliferative and invasive properties of pancreatic cancer cells, and indicated that miR-142 could be a potential therapeutic target for pancreatic cancer.
Coloration mechanisms and phylogeny of Morpho butterflies
Authors: Giraldo M. A. , Yoshioka S. , Liu C. , Stavenga D. G. 
Published: January 2017

ABSTRACT
Morpho butterflies are universally admired for their iridescent blue coloration, which is due to nanostructured wing scales. We performed a comparative study on the coloration of 16 Morpho species, investigating the morphological, spectral and spatial scattering properties of the differently organized wing scales. In numerous previous studies, the bright blue Morpho coloration has been fully attributed to the multi-layered ridges of the cover scales' upper laminae, but we found that the lower laminae of the cover and ground scales play an important additional role, by acting as optical thin film reflectors. We conclude that Morpho coloration is a subtle combination of overlapping pigmented and/or unpigmented scales, multilayer systems, optical thin films and sometimes undulated scale surfaces. Based on the scales' architecture and their organization, five main groups can be distinguished within the genus Morpho, largely agreeing with the accepted phylogeny.
Multilevel Survivability Assessment of Complex Technical Systems with Account for Large-Scale and Structural Hierarchy of Damages and Destruction Accumulation Processes
Authors: Махутов  , Makhutov Nikolay , Резников  , Reznikov D. 
Published: January 2017

Ensuring survivability, defined as the ability of the technical system in a damaged state, to carry out (in full or in part) their
duties and avoid catastrophic damage, is an important element of the complex security problems technosphere objects.
In this paper are considered the basic approaches to quantitative assessment of complex technical systems’ survivability
taking into account that damage accumulation and fracture processes are developed along a broad range of the system’s
scales: starting from the nano-scale level and up to the global structural level of the system. Three basic scales were
single out from the entire spectrum of the system’s scales. These scales allow describe the system failure process. A set of
indexes describing systems’ survivability at the specified above scale levels has been presented. The next basic approaches
to quantitative assessment of complex systems’ survivability have been developed: approaches based on deterministic
and probabilistic assessments of system’s residual strength after macro-defects initiation, as well as integral approaches
based on risk assessment and on estimation of reducing of system’s key strength characteristics when its damage level has
increased.
Ensuring of Professional and Ecological Electromagnetic Safety: Problems, State and Solutions
Authors: Перова  , Perova S. , Походзей  , Pokhodzey L. , Пальцев  , Paltsev Yuriy , Рубцова  , Rubtsova Nina , Токарский  , Tokarskiy A. 
Published: January 2017

Assurance of workers and population’s electromagnetic safety represents a big relevance in connection with the increasing
electromagnetic pollution both of in-plant and natural environment and increase with respect thereto in risk of health loss.
Implementation of the principles for protection against electromagnetic fields (EMF) can be not always realized in practice
by time, distance, and application of collective and individual means of protection. The question of human being’s protection
against EMF has a high relevance especially in connection with potential carcinogenicity of some ranges and modes for EMF
generation. Relevance of enhancement of hygienic standards and control methods for EMF, especially taking into account
determination of values not only for falling energy, but for the absorbed one, has been demonstrated. The developed
modern principle for solution of the problem related to adequate assessment of EMF exposition using a combination of
numerical and experimental dosimetry methods, and investigational studies on animals has been separately considered.
Penyakit Kawasaki
Authors: Kardana Made , Winaya Ida Bagus Agung 
Published: January 2017

Penyakit Kawasaki adalah penyakit akibat vaskulitis akut menyeluruh. Sampai saat ini penyebabnya secara pasti belum diketahui, diduga karena infeksi, toksin atau kelainan imunoregulator. Penyakit ini tersebar luas di seluruh dunia, 80% menyerang anak di bawah usia 5 tahun. Diagnosis ditegakkan apabila terdapat panas lebih dari 5 hari, ditambah 4 dari 5 gejala berikut yaitu injeksi konjungtiva bilateral, mukosa mulut dan faring kemerahan atau pecah-pecah, edema dan atau eritema pada ekstremitas, ruam kulit, limfadenopati servikal yang tidak dapat dijelaskan oleh penyakit lain yang penyebabnya diketahui. Dua puluh sampai 25% dapat berkembang menjadi aneurisma arteri koronaria. Pengobatan aspirin dosis tinggi dan gamma globulin bertujuan untuk mengurangi proses inflamasi pada miokardium dan dinding arteri koronaria dan aspirin dosis rendah untuk menghambat agregasi trombosit. Pembedahan dilakukan apabila gejalanya berkembang menjadi angina dan terdapat bukti obstruksi satu atau lebih arteri koronaria mayor. Prognosis tergantung dari ada tidaknya kelainan arteri koronaria dan kematian sebagian besar akibat infark miokardium.
A Nonlocal Operator Breaking the Keller–Osserman Condition
Authors: Ferreira Raúl , Pérez-Llanos Mayte 
Published: January 2017

Abstract
This work is concerned about the existence of solutions to the nonlocal semilinear problem

{

-

∫

ℝ
N

J
⁢

(

x
-
y

)

⁢

(

u
⁢

(
y
)

-

u
⁢

(
x
)

)

⁢

𝑑
y

+

h
⁢

(

u
⁢

(
x
)

)

=

f
⁢

(
x
)

,

x
∈
Ω

,

u
=
g

,

x
∈

ℝ
N

∖
Ω

,

\left\{\begin{aligned} &\displaystyle{-}\int_{{\mathbb{R}}^{N}}J(x-y)(u(y)-u(x% ))\,dy+h(u(x))=f(x),&&\displaystyle x\in\Omega,\\ &\displaystyle u=g,&&\displaystyle x\in{\mathbb{R}}^{N}\setminus\Omega,\end{% aligned}\right.

verifying that

lim

x
→

∂
⁡
Ω

,

x
∈
Ω

⁡

u
⁢

(
x
)

=

+
∞

{\lim_{x\to\partial\Omega,\,x\in\Omega}u(x)=+\infty}

, known in the literature as large solutions. We find out that the relation between the diffusion and the absorption term is not enough to ensure such existence, not even assuming that the boundary datum g blows up close to

∂
⁡
Ω

{\partial\Omega}

. On the contrary, the role to obtain large solutions is played only by the interior source f, which gives rise to large solutions even without the presence of the absorption. We determine necessary and sufficient conditions on f providing large solutions and compute the blow-up rates of such solutions in terms of h and f. Finally, we also study the uniqueness of large solutions.
Automatische Workflow-Generierung für Engineering-Prozesse
Authors: Seidel Heiko , Mühlhause Mathias , Jäger Tobias , Fay Alexander , Diedrich Christian 
Published: January 2017

Zusammenfassung
Für das Engineering komplexer Automatisierungssysteme können IT-basierte Workflows die Anwender
unterstützen, um die eigenen Aufgaben zu bewältigen und Transparenz im Engineering-Prozess zu schaffen, da in
den kollaborativen Prozessen unterschiedliche Stakeholder miteinander interagieren. Zur IT-Unterstützung von
Engineering-Prozessen können Workflow-Management-Systeme (WfMS) verwendet werden, die gerade durch eine Integration in
CAE-Werkzeuge und damit direktem Zugriff auf deren Funktionen und Daten einen wesentlichen Mehrwert bieten. Gleichzeitig
ist bei der Nutzung von WfMS im Engineering noch keine Lösung bekannt, um flexible Prozesse workflow-gestützt zu
bearbeiten. Da die erfolgreiche Projektabwicklung auch von kundenspezifischen Wünschen abhängt, die auch Anpassungen an
die Abwicklungsprozesse bedingen können, ist die Anforderung, flexible und ad-hoc Workflows bearbeiten zu können,
essentiell im Engineering. Zur Lösung dieses Problems wird im vorliegenden Beitrag ein Konzept beschrieben sowie eine
Realisierung vorgestellt, um im WfMS während der Projektabarbeitung einen Workflow dynamisch an aktuelle Gegebenheiten
anzupassen. Das wesentliche Instrument ist dabei die abzuarbeitenden Engineering-Aktivitäten entsprechend der geänderten
Projektanforderungen automatisch zu generieren und in den laufenden Workflow zu integrieren. Ergebnis ist, dass
Projektierer die aktuell zu bearbeitenden Aktivitäten und simultan die dafür relevante Information bzw. die
benötigte Funktion im CAE-Werkzeug angeboten bekommen.
Einheitliches und durchgängiges Engineering von Steuerungslösungen für hybride Energiesysteme und -netze mittels Energie-Agenten
Authors: Wassermann Erik , Linnenberg Tobias , Törsleff Sebastian , Fay Alexander , Derksen Christian , Loose Nils , Unland Rainer , Ludwig Marcel , Stötzel Marcus , Zdrallek Markus , Heldmaier Wolfram 
Published: January 2017

Zusammenfassung
Im Rahmen des vom BMWi geförderten Projekts Agent.HyGrid werden vereinheitlichte Energie-Agenten als
Steuerungslösung für hybride Energiesysteme und -netze entwickelt und auf ihre Anwendbarkeit hin
untersucht. Hierbei werden sowohl vereinheitlichte Daten- und Verhaltensmodelle entwickelt als auch ein Referenz- und
Entwicklungsprozess entworfen. Mit diesem durchgehenden Entwicklungsprozess soll die Anwendung der
Energie-Agenten, angefangen von der Planungs- und Simulationsphase bis hin zum realen Einsatz im physischen
Vor-Ort-System, ermöglicht werden. Als Energie-Agent wird dabei grundsätzlich ein autonomes, dezentral
operierendes Software-System verstanden, das unabhängig von der Sparte bzw. vom Energieträger auf
mehreren Ebenen eines Energie-Verteilnetzes eingesetzt werden kann. Durch die Kombination unterschiedlicher
Energieträger sollen insbesondere volatile Energieerzeugungsanlagen, wie Windkraft- und Solaranlagen, besser ins
Energienetz integriert werden. Die Herausforderungen des Projekts liegen vor allem in der vereinheitlichten Modellierung
unterschiedlicher Energieträger und -umwandlungsanlagen sowie in der Überbrückung der Lücke zwischen
Simulation und der realen Anwendung vor Ort. Dieser Artikel stellt die bisherigen Erkenntnisse in Hinblick auf die
Anwendung des Entwicklungsprozesses und des einheitlichen Datenmodells dar.
Design and Fabrication of a Novel Compact Bandpass Filter to Improve Spurious-Free Band
Authors: Rezaee Payman , Höft Michael 
Published: January 2017

AbstractIn this paper, a new microstrip slow wave open loop resonator is proposed. This resonator overcomes the substantial limitation of the conventional slow wave open loop resonators, which limits the spurious-free band of those resonators. The new proposed resonator improves the spurious-free band up to 8 times of the fundamental frequency, which is 3.16 times of the conventional slow wave open loop resonators. For the proposed resonator the coupling factor and the external quality factor curves, which are the design curves of a narrowband filter, are extracted using a full wave simulator, i. e. HFSS. These curves are utilized for the design of two three-pole Chebyshev bandpass filters. One of these filters is fabricated. Simulation and measurement results are reported which are in good agreement. Designed filters provide 75 % and 83 % of footprint reduction in comparison with the conventional open loop resonator filters. Different parameters which can improve the spurious-free band are explained in the paper.
Energy Dissipation Rate in an Agitated Crucible Containing Molten Metal
Authors: Li Tao , Shimasaki Shin-ichi , Narita Shunsuke , Taniguchi Shoji 
Published: January 2017

AbstractThe energy dissipation rate (EDR) is an important parameter for characterizing the behavior of inclusion coagulation in agitated molten metal. To clarify the inclusion coagulation mechanism, we review previous water model studies by particularly focusing on the relation between the impeller torque and the EDR of the fluid, which indicates the ratio of energy dissipated in the viscous medium to the energy inputted by the rotating impeller. In the present study, simulations coupled with experiments were performed to determine the relation between the torque and the effective EDR for water and liquid Al in crucibles with and without baffles.
The third-time chronic myeloid leukemia in lymphoblastic crisis with ABL1 kinase mutation induced by decitabine, dexamethason combined with nilotinib and dasatinib
Authors: Wang Suli , Qiao Chun , Zhu Yu , Shen Wenyi , He Guangsheng , Li Jianyong 
Published: January 2017

Abstract
Blast crisis (BC) is the major remaining challenge in the management of chronic myeloid leukemia (CML). The prognosis of the BC patient who carries ABL kinase mutation is very poor. One patient, with lymphoid CML-BC third time, was detected with T315A/F359I/M244V compound mutation by direct sequencing after treatment with tyrosine kinase inhibitions three years. The patient was treated with decitabine, dexamethasone, in combination with nilotinib and dasatinib. Then this patient received a complete hematologic response and cytogenetic response after two cycles of treatment.