bluuebunny/crossref_metadata_2025_split huggingface dataset:
Une orthodontie contemporaine fondée sur l'harmonie esthétique et sur la biomécanique. Un entretien avec Ravindra Nanda
Authors: Nanda Ravindra , Amat Philippe 
Published: January 2018

Le Pr Ravindra Nanda a obtenu une licence et une maîtrise en dentisterie et en orthodontie duKing George's Medical College, Lucknow University. En 1967, il a intégré l'Université Catholique de Nimègue, aux Pays-Bas, où il a obtenu un doctorat en philosophie en 1969. Il a rejoint la nouvelle école dentaire de Loyola à Chicago en 1970, après avoir occupé le poste de Professeur assistant en orthodontie dans le service dirigé par Frans van der Linden. En 1972, il fut promu au Département d'Orthodontie de l'Université du Connecticut à Farmington, CT, et y reçu son certificat en orthodontie sous la direction de Charles Burstone. Professeur adjoint, puis professeur titulaire à partir de 1979, il a assumé le poste de Chef du Département d'Orthodontie à partir de 1992 et a été promu pour diriger le Département des Sciences Craniofaciales en 2004, dont les divisions de chirurgie orale et maxillo-faciale, de dentisterie pédiatrique, de l'enseignement supérieur en dentisterie générale et en orthodontie.Il est membre et ancien président de la composante Atlantique Nord de laEdward H. Angle Society of Orthodontists. Il occupe actuellement la fonction de rédacteur en chef deProgress in Orthodontics, de rédacteur associé duJournal of Clinical Orthodonticset est membre du comité éditorial de neuf revues d'orthodontie nationales et internationales. Il est membre de l'Association dentaire américaine, de l'Association dentaire de l'État du Connecticut, de laHartford Dental Society, de l'Association américaine des orthodontistes, de la Société européenne d'orthodontie, de l'Association internationale de recherche dentaire et duCollege of Diplomates of American Board of Orthodontists.Il a rédigé et publié sept manuels et plus de 200 articles dans des revues à comité de lecture. Il a donné des conférences magistrales dans plus de 40 pays et a reçu de nombreux prix et honneurs pour ses contributions en dentisterie et en orthodontie, aux États-Unis et de la part d'organisations internationales d'orthodontie. Il est membre d'honneur desJordan Orthodontic Society,Czech Orthodontic Society,Taiwanese Orthodontic Society,Central American Orthodontics Societyet membre d'honneur à vie de l'Indian Orthodontic Society.Ravindra Nanda a été honoré duLife Time Achievement Award(University of Connecticut Foundation), et il estSenior Research Fellow(Japan Promotion for Science, Sendai, Japan − Tohoku University). Il a prononcé de nombreuses conférences d'honneur : laJohn Taylor Lecture, lors de la réunion annuelle del'Australian Society of Orthodontics Foundation, laSheldon Friel Memorial Lecturelors de la réunion annuelle del'European Orthodontic Society, laGordon Kirkness Memorial Lecturelors de la réunion annuelle de l'Australian Society of Orthodontics, laJohn Mershon Memorial Lecture, Boston, Massachusetts lors de la réunion annuelle de l'American Association of Orthodonticset laWendell L. Wylie Memorial Lecture, à l'Université de San Francisco, Californie.
Key comparison BIPM.RI(I)-K5 of the air-kerma standards of the SMU, Slovakia and the BIPM in 137Cs gamma radiation
Authors: Kessler C , Burns D , Durný N 
Published: January 2018

The first direct comparison of the standards for air kerma of the Slovak Institute of Metrology (SMU), Slovakia and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 137Cs radiation beam of the BIPM in June 2017. The comparison result, evaluated as a ratio of the SMU and the BIPM standards for air kerma, is 1.0051 with a combined standard uncertainty of 2.7 × 10−3. The results for an indirect comparison made at the same time are consistent with the direct results at the level of 2 parts in 104. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
International comparison CCQM-K119 liquefied petroleum gas
Authors: Brewer P J , Downey M L , Atkins E , Brown R J C , Brown A S , Zalewska E T , van der Veen A M H , Smeulders D E , McCallum J B , Satumba R T , Kim Y D , Kang N , Bae H K , Woo J C , Konopelko L A , Popova T A , Meshkov A V , Efremova O V , Kustikov Y 
Published: January 2018

Liquefied hydrocarbon mixtures with traceable composition are required in order to underpin measurements of the composition and other physical properties of LPG (liquefied petroleum gas), thus meeting the needs of an increasingly large industrial market.
This comparison aims to assess the analytical capabilities of laboratories for measuring the composition of a Liquid Petroleum Gas (LPG) mixture when sampled in the liquid phase from a Constant Pressure Cylinder. Mixtures contained ethane, propane, propene, i-butane, n-butane, but-1-ene and i-pentane with nominal amount fractions of 2, 71, 9, 4, 10, 3 and 1 cmol mol−1 respectively.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Retailer Proximity and Nutrition Program Redemptions: Evidence From the Summer Electronic Benefit Transfer For Children Program
Authors: Furey Jane , Klerman Jacob Alex , Grindal Todd 
Published: January 2018

AbstractAlthough nearly all Supplemental Nutrition Assistance Program benefits are redeemed, a moderate share of Special Supplemental Nutrition Program for Women, Infant, and Children (WIC) benefits go unredeemed. Some hypothesize that the redemption rate differences are due to the lower density of WIC‐authorized retailers. For the 2012 Summer Electronic Benefit Transfer for Children sites, this paper finds no consistent evidence of a relationship between redemption rates and retailer proximity. In fact, households often travel past the closest participating retailer to redeem their benefits. These findings are consistent with recent “food deserts” literature, which suggests that correlations between retailer environment and nutritional outcomes are not causal. Rather, it appears that differences in redemption rates may be related to the restrictions on what foods can be redeemed in what form with WIC.
Presence of Myocardial Damage Predicts Future Development of Hypertension in a Normotensive Japanese General Population: The Yamagata (Takahata) Study
Authors: Honda Yuki , Watanabe Tetsu , Tamura Harutoshi , Nishiyama Satoshi , Takahashi Hiroki , Arimoto Takanori , Shishido Tetsuro , Miyamoto Takuya , Shibata Yoko , Konta Tsuneo , Kayama Takamasa , Kubota Isao 
Published: January 2018

Abstract

BACKGROUND
A modest rise in blood pressure (BP) reportedly increases cardiovascular mortality despite not reaching obvious hypertension, suggesting that target organ damages are latently induced by slight BP rising. The goal of this study was to determine whether presence of subclinical myocardial damage can predict the future development of hypertension in the normotensive general population.

METHODS AND RESULTS
The cohort study was conducted with subjects who participated in a community-based annual health check. Normotensive subjects without prior cardiovascular diseases at baseline were eligible for analyses (n = 524, mean age 58 ± 9 years; 53% women). We measured heart-type fatty acid binding protein (H-FABP) at baseline as a biomarker of ongoing myocardial damage. Longitudinal changes in BP were examined during median follow-up period of 6.2 years, and we investigated the association between the baseline H-FABP level and longitudinal BP changes.

RESULTS
During the follow-up, 177 subjects (34%) developed hypertension. In multivariate Cox proportional hazard analysis adjusted for potential confounders including age and baseline BP, presence of myocardial damage was significantly associated with the development of hypertension (hazard ratio 1.80, 95% confidence interval, 1.26–2.54; P = 0.0014). Furthermore, relative risk of myocardial damage for incident hypertension was higher in younger subjects and lower BP category.

CONCLUSIONS
Presence of subclinical myocardial damage was independently associated with the future development of hypertension in the normotensive general population.
Characteristics and evolution of the ecosystem of software tools supporting research in molecular biology
Authors: Pazos Florencio , Chagoyen Monica 
Published: January 2018

Abstract
Daily work in molecular biology presently depends on a large number of computational tools. An in-depth, large-scale study of that ‘ecosystem’ of Web tools, its characteristics, interconnectivity, patterns of usage/citation, temporal evolution and rate of decay is crucial for understanding the forces that shape it and for informing initiatives aimed at its funding, long-term maintenance and improvement. In particular, the long-term maintenance of these tools is compromised because of their specific development model. Hundreds of published studies become irreproducible de facto, as the software tools used to conduct them become unavailable. In this study, we present a large-scale survey of >5400 publications describing Web servers within the two main bibliographic resources for disseminating new software developments in molecular biology. For all these servers, we studied their citation patterns, the subjects they address, their citation networks and the temporal evolution of these factors. We also analysed how these factors affect the availability of these servers (whether they are alive). Our results show that this ecosystem of tools is highly interconnected and adapts to the ‘trendy’ subjects in every moment. The servers present characteristic temporal patterns of citation/usage, and there is a worrying rate of server ‘death’, which is influenced by factors such as the server popularity and the institutions that hosts it. These results can inform initiatives aimed at the long-term maintenance of these resources.
pyHVis3D: visualising molecular simulation deduced H-bond networks in 3D: application to T-cell receptor interactions
Authors: Knapp Bernhard , Alcala Marta , Zhang Hao , West Clare E , van der Merwe P Anton , Deane Charlotte M 
Published: January 2018

Abstract

Motivation
Hydrogen bonds (H-bonds) play an essential role for many molecular interactions but are also often transient, making visualising them in a flexible system challenging.

Results
We provide pyHVis3D which allows for an easy to interpret 3D visualisation of H-bonds resulting from molecular simulations. We demonstrate the power of pyHVis3D by using it to explain the changes in experimentally measured binding affinities for three T-cell receptor/peptide/MHC complexes and mutants of each of these complexes.

Availability and implementation
pyHVis3D can be downloaded for free from http://opig.stats.ox.ac.uk/resources.

Supplementary information
Supplementary data are available at Bioinformatics online.
MAGNAMWAR: an R package for genome-wide association studies of bacterial orthologs
Authors: Sexton Corinne E , Smith Hayden Z , Newell Peter D , Douglas Angela E , Chaston John M 
Published: January 2018

Abstract

Summary
Here we report on an R package for genome-wide association studies of orthologous genes in bacteria. Before using the software, orthologs from bacterial genomes or metagenomes are defined using local or online implementations of OrthoMCL. These presence–absence patterns are statistically associated with variation in user-collected phenotypes using the Mono-Associated GNotobiotic Animals Metagenome-Wide Association R package (MAGNAMWAR). Genotype-phenotype associations can be performed with several different statistical tests based on the type and distribution of the data.

Availability and implementation
MAGNAMWAR is available on CRAN.
A network approach to exploring the functional basis of gene–gene epistatic interactions in disease susceptibility
Authors: Yip Danny Kit-Sang , Chan Landon L , Pang Iris K , Jiang Wei , Tang Nelson L S , Yu Weichuan , Yip Kevin Y 
Published: January 2018

Abstract

Motivation
Individual genetic variants explain only a small fraction of heritability in some diseases. Some variants have weak marginal effects on disease risk, but their joint effects are significantly stronger when occurring together. Most studies on such epistatic interactions have focused on methods for identifying the interactions and interpreting individual cases, but few have explored their general functional basis. This was due to the lack of a comprehensive list of epistatic interactions and uncertainties in associating variants to genes.

Results
We conducted a large-scale survey of published research articles to compile the first comprehensive list of epistatic interactions in human diseases with detailed annotations. We used various methods to associate these variants to genes to ensure robustness. We found that these genes are significantly more connected in protein interaction networks, are more co-expressed and participate more often in the same pathways. We demonstrate using the list to discover novel disease pathways.

Contact
kevinyip@cse.cuhk.edu.hk

Supplementary information
Supplementary data are available at Bioinformatics online.
PyChimera: use UCSF Chimera modules in any Python 2.7 project
Authors: Rodríguez-Guerra Pedregal Jaime , Maréchal Jean-Didier 
Published: January 2018

AbstractMotivationUCSF Chimera is a powerful visualization tool remarkably present in the computational chemistry and structural biology communities. Built on a C++ core wrapped under a Python 2.7 environment, one could expect to easily import UCSF Chimera’s arsenal of resources in custom scripts or software projects. Nonetheless, this is not readily possible if the script is not executed within UCSF Chimera due to the isolation of the platform. UCSF ChimeraX, successor to the original Chimera, partially solves the problem but yet major upgrades need to be undergone so that this updated version can offer all UCSF Chimera features.ResultsPyChimera has been developed to overcome these limitations and provide access to the UCSF Chimera codebase from any Python 2.7 interpreter, including interactive programming with tools like IPython and Jupyter Notebooks, making it easier to use with additional third-party software.Availability and implementationPyChimera is LGPL-licensed and available at https://github.com/insilichem/pychimera.Supplementary informationSupplementary data are available at Bioinformatics online.
Older Patients Have Better Pain Outcomes Following Microvascular Decompression for Trigeminal Neuralgia
Authors: Bick Sarah K , Huie David , Sneh Gabriel , Eskandar Emad N 
Published: January 2018

Abstract

BACKGROUND
Trigeminal neuralgia (TN) increases in prevalence with age. Although microvascular decompression (MVD) is the most effective long-term operative treatment for TN, its use in older patient populations has been debated due to its invasive nature. Recent studies have demonstrated safety of MVD in older patients; however, efficacy data are more limited.

OBJECTIVE
To determine the relationship between age and pain outcomes following MVD for TN.

METHODS
Subjects underwent MVD for TN at our institution between 1/1/2004 and 12/31/2013, had typical TN, and demonstrated neurovascular compression on preoperative imaging. We performed a retrospective case series study by reviewing the electronic medical records and performing phone interviews to determine long-term outcomes. We divided patients into 2 groups for analysis, under 60 and 60 yr of age and older.

RESULTS
One hundred twenty-four subjects were included in the study, 82 under 60, and 42 60 yr of age and older. The average length of follow-up was 42.4 mo. Patients in the older age group had average pain score of 1.57 at most recent follow-up, while for the younger age group it was 2.18 (P = .0084). Multiple regression analysis found that older age, male gender, and preoperative medication responsiveness were significantly correlated with lower long-term pain scores, while V2 dermatome involvement was correlated with higher long-term pain scores.

CONCLUSION
Patients 60 yr of age and older have significantly better long-term pain outcomes following MVD than younger patients.
Acute Appendicitis as the Initial Clinical Presentation of Primary HIV-1 Infection
Authors: Schleimann Mariane H , Leth Steffen , Krarup Astrid R , Mortensen Jesper , Barstad Bente , Zaccarin Matthias , Denton Paul W , Mohey Rajesh 
Published: January 2018

AbstractWe report a case of an adolescent who presented at our emergency department with acute abdominal pain. While the initial diagnosis was acute appendicitis, a secondary and coincidental diagnosis of primary HIV-1 infection was made. Concurrent and subsequent clinical and molecular biology findings form the basis of our argument that primary HIV-1 infection was the cause of acute appendicitis in this individual.
Magnetic field analysis of the bow and terminal shock of the SS 433 jet
Authors: Sakemi Haruka , Machida Mami , Akahori Takuya , Nakanishi Hiroyuki , Akamatsu Hiroki , Kurahara Kohei , Farnes Jamie 
Published: January 2018

Abstract
We report a polarization analysis of the eastern region of W 50, observed with the Australia Telescope Compact Array (ATCA) at 1.4–3.0 GHz. In order to study the physical structures in the region where the SS 433 jet and W 50 interact, we obtain an intrinsic magnetic field vector map of that region. We find that the orientation of the intrinsic magnetic field vectors are aligned along the total intensity structures, and that there are characteristic, separate structures related to the jet, the bow shock, and the terminal shock. The Faraday rotation measures (RMs), and the results of Faraday tomography suggest that a high-intensity, filamentary structure in the north–south direction of the eastern-edge region can be separated into at least two parts to the north and south. The results of Faraday tomography also show that there are multiple components along the line of sight and/or within the beam area. In addition, we analyze the X-ray ring-like structure observed with XMM-Newton. While the possibility still remains that this X-ray ring is “real”, it seems that the structure is not ring-like at radio wavelengths. Finally, we suggest that the structure is a part of the helical structure that coils the eastern ear of W 50.
Self-help cognitive behavior therapy for working women with problematic hot flushes and night sweats (MENOS@Work): a multicenter randomized controlled trial
Authors: Hardy Claire , Griffiths Amanda , Norton Sam , Hunter Myra S. 
Published: January 2018

Abstract

Objective:
The aim of the study was to examine the efficacy of an unguided, self-help cognitive behavior therapy (SH-CBT) booklet on hot flush and night sweat (HFNS) problem rating, delivered in a work setting.

Methods:
Women aged 45 to 60 years, having 10 or more problematic HFNS a week, were recruited to a multicenter randomized controlled trial, via the occupational health/human resources departments of eight organizations. Participants were 1:1 randomized to SH-CBT or no treatment waitlist control (NTWC). The primary outcome was HFNS problem rating; secondary outcomes included HFNS frequency, work and social adjustment, sleep, mood, beliefs and behaviors, and work-related variables (absence, performance, turnover intention, and work impairment due to presenteeism). Intention-to-treat analysis was used, and between-group differences estimated using linear mixed models.

Results:
A total of 124 women were randomly allocated to SH-CBT (n = 60) and NTWC (n = 64). 104 (84%) were assessed for primary outcome at 6 weeks and 102 (82%) at 20 weeks. SH-CBT significantly reduced HFNS problem rating at 6 weeks (SH-CBT vs NTWC adjusted mean difference, −1.49; 95% CI, −2.11 to −0.86; P < 0.001) and at 20 weeks (−1.09; 95% CI, −1.87 to −0.31; P < 0.01). SH-CBT also significantly reduced HFNS frequency, improved work and social adjustment; sleep, menopause beliefs, HFNS beliefs/behaviors at 6 and 20 weeks; improved wellbeing and somatic symptoms and reduced work impairment due to menopause-related presenteeism at 20 weeks, compared with the NTWC. There was no difference between groups in other work-related outcomes.

Conclusions:
A brief, unguided SH-CBT booklet is a potentially effective management option for working women experiencing problematic HFNS.
An In-Vitro Insertion-Force Study of Magnetically Guided Lateral-Wall Cochlear-Implant Electrode Arrays
Authors: Leon Lisandro , Warren Frank M. , Abbott Jake J. 
Published: January 2018

Hypothesis:
Insertion forces can be reduced by magnetically guiding the tip of lateral-wall cochlear-implant electrode arrays during insertion via both cochleostomy and the round window.

Background:
Steerable electrode arrays have the potential to minimize intracochlear trauma by reducing the severity of contact between the electrode-array tip and the cochlear wall. However, steerable electrode arrays typically have increased stiffness associated with the steering mechanism. In addition, steerable electrode arrays are typically designed to curve in the direction of the basal turn, which is not ideal for round-window insertions, as the cochlear hook's curvature is in the opposite direction. Lateral-wall electrode arrays can be modified to include magnets at their tips, augmenting their superior flexibility with a steering mechanism. By applying magnetic torque to the tip, an electrode array can be navigated through the cochlear hook and the basal turn.

Methods:
Automated insertions of candidate electrode arrays are conducted into a scala-tympani phantom with either a cochleostomy or round-window opening. The phantom is mounted on a multi-degree-of-freedom force sensor. An external magnet applies the necessary magnetic bending torque to the magnetic tip of a modified clinical electrode array, coordinated with the insertion, with the goal of directing the tip down the lumen. Steering of the electrode array is verified through a camera.

Results:
Statistical t-test results indicate that magnetic guidance does reduce insertion forces by as much as 50% with certain electrode-array models. Direct tip contact with the medial wall through the cochlear hook and the lateral wall of the basal turn is completely eliminated. The magnetic field required to accomplish these insertions varied from 77 to 225 mT based on the volume of the magnet at the tip of the electrode array. Alteration of the tip to accommodate a tiny magnet is minimal and does not change the insertion characteristic of the electrode array unless the tip shape is altered.

Conclusion:
Magnetic guidance can eliminate direct tip contact with the medial walls through the cochlear hook and the lateral walls of the basal turn. Insertion-force reduction will vary based on the electrode-array model, but is statistically significant for all models tested. Successful steering of lateral-wall electrode arrays is accomplished while maintaining its superior flexibility.