bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interhemispheric characterization of small vessel disease imaging markers after subcortical infarct
Authors: Valdés Hernández Maria del C. , Qiu Xinyi , Wang Xin , Wiseman Stewart , Sakka Eleni , Maconick Lucy C. , Doubal Fergus , Sudlow Cathie L. M. , Wardlaw Joanna M. 
Published: November 2016

AbstractBackgroundIn structural Magnetic Resonance Imaging (MRI) of patients with a recent small subcortical infarct (RSSI) and small vessel disease (SVD) imaging markers coexist. However, their spatial distribution and prevalence with respect to the hemisphere of the RSSI remain unknown.Materials and MethodsFrom brain MRI in 187 patients with an acute lacunar ischemic stroke clinical syndrome and a relevant diffusion weighted imaging (DWI)‐positive lesion, we semiautomatically extracted the RSSI, microbleeds, lacunes, old cortical infarcts, and white matter hyperintensities (WMH) using optimized thresholding in the relevant sequences, and rated the load of perivascular spaces. We registered all images to an age‐relevant brain template and calculated the probability distribution of all SVD markers mentioned for patients who had the RSSI in each hemisphere separately. We used the Wilcoxon and chi‐squared tests to compare the volumes and frequencies of occurrence, respectively, of the SVD markers between hemispheres throughout the sample.ResultsFifty‐two percent patients (n = 97) had the RSSI in the left hemisphere, 42% (n = 78) in the right, 2.7% (n = 5) in both, and 3.7% (n = 7) in the cerebellum or brainstem. There was no significant difference in RSSI frequency between left and right hemispheres (p = .10) in the sample. The median volume of the RSSI (expressed as a percentage of the total intracranial volume) was 0.05% (IQR = 0.06). There was no difference in median percent volume of the right RSSIs versus left (p = .16). Neither was there a significant interhemispheric difference in the volume of any of the SVD markers regardless of the location of the RSSI and they were equally distributed in both hemispheres.ConclusionAssessment of SVD imaging markers in the contralateral hemisphere could be used as a proxy for the SVD load in the whole brain to avoid contamination by the RSSI of the measurements, especially of WMH.
A Highly Porous Carbon Support Rich in Graphitic‐N Stabilizes Copper Nanocatalysts for Efficient Ethanol Dehydrogenation
Authors: Zhang Peng , Wang Qing‐Nan , Yang Xia , Wang Dongqi , Li Wen‐Cui , Zheng Yanping , Chen Mingshu , Lu An‐Hui 
Published: November 2016

AbstractThe dehydrogenation of bioethanol to acetaldehyde and hydrogen is a sustainable process, owing to the atom‐economical transformation and easy separation of the products. However, oxide‐supported Cu catalysts show a low selectivity to acetaldehyde because of considerable side reactions caused by their oxygen‐rich surfaces. A conventional carbon‐supported Cu catalyst shows high selectivity, but is quickly deactivated owing to the migration and agglomeration of copper particles. Here, we have produced a highly porous nitrogen‐rich carbon support that contains 6.2 wt % N and can nicely disperse and stabilize Cu nanoparticles (∼6.3 nm). If used for ethanol dehydrogenation, approximately 98 % selectivity to acetaldehyde has been achieved, with excellent anti‐agglomeration ability for as long as 500 min. X‐ray photoelectron spectroscopy (XPS) data prove that electrons transfer to the Cu particles from the N sites. Theoretical calculations further show that nitrogen sites enhance the adsorption of Cu20 clusters and can stabilize them against coalescence and that graphitic‐N sites (approximately 40 % of total N content) are the most significant.
Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site
Authors: Murarka Sandip , Martín‐Gago Pablo , Schultz‐Fademrecht Carsten , Al Saabi Alaa , Baumann Matthias , Fansa Eyad K. , Ismail Shehab , Nussbaumer Peter , Wittinghofer Alfred , Waldmann Herbert 
Published: November 2016

AbstractThe K‐Ras GTPase is a major target in anticancer drug discovery. However, direct interference with signaling by K‐Ras has not led to clinically useful drugs yet. Correct localization and signaling by farnesylated K‐Ras is regulated by the prenyl binding protein PDEδ. Interfering with binding of PDEδ to K‐Ras by means of small molecules provides a novel opportunity to suppress oncogenic signaling. Here we describe the identification and structure‐guided development of novel K‐Ras–PDEδ inhibitor chemotypes based on pyrrolopyridazinones and pyrazolopyridazinones that bind to the farnesyl binding pocket of PDEδ with low nanomolar affinity. We delineate the structure–property relationship and in vivo pharmacokinetic (PK) and toxicokinetic (Tox) studies for pyrazolopyridazinone‐based K‐Ras–PDEδ inhibitors. These findings may inspire novel drug discovery efforts aimed at the development of drugs targeting oncogenic Ras.
Heavier Group 13 Metal(I) Heterocycles Stabilized by Sterically Demanding Diiminophosphinates: A Structurally Characterized Monomer–Dimer Pair For Gallium
Authors: Hawley Andrew L. , Ohlin C. André , Fohlmeister Lea , Stasch Andreas 
Published: November 2016

AbstractWe have synthesized and characterized the monomeric diiminophosphinate‐stabilized Group 13 metal(I) complexes [DipLE:], DipL=Ph2P(NDip)2, Dip=2,6‐iPr2C6H3; E=Ga (1), In (2) and Tl (3). In addition, we structurally characterized the dimeric complex [(DipLGa)2], 12. Similar synthetic attempts using MesL=Ph2P(NMes)2, Mes=2,4,6‐Me3C6H2 afforded product mixtures from which the mixed oxidation state species [(MesL)3Ga4I3] 4 was isolated. [DipLGa:] 1 is converted with dry air to the gallium(III) oxide species [(DipLGaO)2] 5. Density Functional Theory studies on [DipLE:] and [(DipLE)2], E=Al−Tl, shed light on the bonding in these compounds and show that the newly formed E−E bonding interactions can be described as weak single σ‐bond with no significant π‐bonding contribution for E=Al, Ga. A large contribution to the dimer binding enthalpies results from London dispersion forces.
Bifunctional Carbon‐Dot‐WS2 Nanorods for Photothermal Therapy and Cell Imaging
Authors: Nandi Sukhendu , Bhunia Susanta Kumar , Zeiri Leila , Pour Maayan , Nachman Iftach , Raichman Daniel , Lellouche Jean‐Paul Moshe , Jelinek Raz 
Published: November 2016

AbstractMultifunctional nanoparticles have attracted significant interest as biomedical vehicles, combining diagnostic, imaging, and therapeutic properties. We describe herein the construction of new nanoparticle conjugates comprising WS2 nanorods (NRs) coupled to fluorescent carbon dots (C‐dots). We show that the WS2‐C‐dot hybrids integrate the unique physical properties of the two species, specifically the photothermal activity of the WS2 NRs upon irradiation with near‐infrared (NIR) light and the excitation‐dependent luminescence emission of the C‐dots. The WS2‐C‐dot NRs have been shown to be non‐cytotoxic and have been successfully employed for multicolour cell imaging and targeted cell killing under NIR irradiation, pointing to their potential utilization as effective therapeutic vehicles.
ChemInform Abstract: Crystal Structure of BaMnB2O5 Containing Structurally Isolated Manganese Oxide Sheets.
Authors: Maschmeyer Elizabeth M. , Sanjeewa Liurukara D. , Ranmohotti Kulugammana G. S. 
Published: November 2016

AbstractThe title compound is prepared by melting a 2:1:1 molar mixture of MnO, BaO, and B2O3 in a CsCl/RbCl flux (evacuated silica tubes, 1.
ChemInform Abstract: Hydrothermal Synthesis, Structural and Luminescent Properties of a Cr3+ Doped MgGa2O4 Near‐Infrared Long Lasting Nanophospor.
Authors: Mondal Amba , Das Sourav , Manam J. 
Published: November 2016

AbstractPolycrystalline samples of MgGa2‐xO4:xCr3+ (x = 0—0.01) are prepared by hydrothermal reaction of stoichiometric amounts of the metal nitrates (pH 9—9.5 adjusted with NH4OH, autoclave, 220 °C, 10 h) followed by annealing (700 °C, 2 h).
ChemInform Abstract: Concerted Rattling in CsAg5Te3 Leading to Ultralow Thermal Conductivity and High Thermoelectric Performance.
Authors: Wu Li‐Ming , et al.  
Published: November 2016

AbstractPure samples of the title p‐type material are obtained from stoichiometric mixtures of Ag, Te, and Cs2Te3 (silica tubes, 1073 K, 2 h).
ChemInform Abstract: Exploration of K2Ti8O17 as an Anode Material for Potassium‐Ion Batteries.
Authors: Han Jin , Xu Maowen , Niu Yubin , Li Guan‐Nan , Wang Minqiang , Zhang Yan , Jia Min , Li Chang ming 
Published: November 2016

AbstractPolycrystalline K2Ti8O17 is prepared by hydrothermal reaction of (BuO)4Ti and KOH in a 1:1 mixture of ethylene glycol and H2O (autoclave, 200 °C, 20 h) followed by calcination in air (700 °C, 12 h).
ChemInform Abstract: NO Reduction Utilizing Complex Oxide Catalysts.
Authors: Stamm Masias Kimber L. , Peck Torin C. , Fanson Paul T. 
Published: November 2016

AbstractIn view of reducing NOx levels in automotive exhaust gases under excess O2, a series of Rh, Ir, or Pd‐doped (10 mol%) BaCeO3 perovskites are prepared by calcination of Ba(NO3)2, Ce(NO3)3, and IrCl3, RhBr3, or Pd(NO3)2 (air, 1000 °C, 46 h).
ChemInform Abstract: Two 1‐D Krebs‐Type Heteropolyoxotungstates Based on [X2W21O72Na(OH)2]13‐ (X: SbIII, BiIII) Units.
Authors: Li Hailou , Chang Shenzhen , Ma Xing , Liu Jinglin , Luo Jie , Zhao Junwei 
Published: November 2016

Abstract[Me2NH2]2Na11 [X2W21NaO72(OH)2] ·34H2O (X: SbIII (I), BiIII (II)) are prepared by a one‐pot self‐assembly of aqueous solutions of Na2WO4, NaOAc, and Me2NH2Cl to which a HCl solution of SbCl3 (or Bi(NO3)3 and Zr(NO3)4 for (II)) is added dropwise.
ChemInform Abstract: Me2(CH2Cl)SiCN: Bifunctional Cyanating Reagent for the Synthesis of Tertiary Alcohols with a Chloromethyl Ketone Moiety via Ketone Cyanosilylation.
Authors: Zeng Xing‐Ping , Zhou Jian 
Published: November 2016

AbstractA novel bifunctional silyl reagent is introduced for highly enantioselective cyanosilylation of ketones.
ChemInform Abstract: First Iodine/IL‐Catalyzed Carbohydrate Activation as Aldehyde Equivalent for [C+2C+N] Construction of β‐Lactam Ring.
Authors: Rai Vijai K. , Sharma Bhaskar , Sharoff Vidya R. , Rai Ankita 
Published: November 2016

AbstractA facile protocol is developed for the synthesis of imino‐ and thiosugar annulated β‐lactams from masked amino‐ or mercapto acids, aromatic amines, and D‐xylose.
ChemInform Abstract: Cu(I)‐Catalyzed Enantioselective Friedel—Crafts Alkylation of Indoles with 2‐Aryl‐N‐sulfonylaziridines as Alkylating Agents.
Authors: Ge Chen , Liu Ren‐Rong , Gao Jian‐Rong , Jia Yi‐Xia 
Published: November 2016

AbstractThe scalable procedure provides tryptamine derivatives in high yields and with high enantioselectivities.
ChemInform Abstract: Catalyst‐Free Halogenation of α‐Diazocarbonyl Compounds with N‐Halosuccinimides: Synthesis of 3‐Halooxindoles or Vinyl Halides.
Authors: Ma Chaoqun , Xing Dong , Hu Wenhao 
Published: November 2016

AbstractThe scalable reaction has a broad substrate scope.
ChemInform Abstract: Simple Modular Synthetic Approaches to Asymmetric NN′N′′, NN′C, or NN′P‐Type Amido Pincer Ligands: Synthesis, Characterization, and Preliminary Ligation Studies.
Authors: Herasymchuk Khrystyna , Huynh Jennifer , Lough Alan J. , Roces Fernandez Laura , Gossage Robert A. 
Published: November 2016

AbstractA palladium complex of a newly prepared NN′N′′‐pincer ligand proves as an active catalyst for the allylation of benzaldehydes by allyltributylstannane.
ChemInform Abstract: Facile Synthesis of Fluorovinyl‐Containing Lactams via Ring‐Closing Metathesis of N‐Substituted 2‐Fluoroallylamides.
Authors: Li Yang , Li Kai , Wu Yue , Ma Qiaoning , Lei Xinsheng 
Published: November 2016

AbstractAminolysis of 2‐fluoroacrylate followed by selective reduction of the amide group provides N‐substituted (2‐fluoroallyl)amines.
ChemInform Abstract: Rhodium‐Catalyzed Hydrocarboxylation of Olefins with Carbon Dioxide.
Authors: Kawashima Shingo , Aikawa Kohsuke , Mikami Koichi 
Published: November 2016

AbstractThe catalytic hydrocarboxylation of styrene derivatives and α,β‐unsaturated carbonyl compounds with CO2 in the presence of an air‐stable rhodium catalyst is explored.
ChemInform Abstract: Stereoselective Construction of anti‐ and syn‐1,2‐Diol Structures via Decarbonylative Radical Coupling of α‐Alkoxyacyl Tellurides.
Authors: Matsumura Shoko , Matsui Yuki , Nagatomo Masanori , Inoue Masayuki 
Published: November 2016

AbstractStereoselective coupling reactions of tartrate‐derived α‐alkoxyacyl tellurides with electron‐deficient C=N and C=C double bonds afford the corresponding protected 1,2‐diols containing electron‐withdrawing groups under mild conditions.
ChemInform Abstract: Mild and Low‐Pressure fac‐Ir(ppy)3‐Mediated Radical Aminocarbonylation of Unactivated Alkyl Iodides Through Visible‐Light Photoredox Catalysis.
Authors: Chow Shiao Y. , Stevens Marc Y. , Aakerbladh Linda , Bergman Sara , Odell Luke R. 
Published: November 2016

AbstractThe formation of the title compounds is carried out in a two‐chambered system: first, an alkyl radical is generated which subsequently is subjected to aminocarbonylation, where CO is released from molybdenum hexacarbonyl.
ChemInform Abstract: Multicomponent Reaction of Pyridine, Acetoacetamide/Benzoylacetamides and Sulfuryl Chlorides: Regioselective Construction of 4‐Olefinated Dihydropyridines.
Authors: Zhao Xuna , Liu Tong‐Xin , Ma Nana , Zhang Zhiguo , Zhang Guisheng 
Published: November 2016

AbstractA one‐pot, three‐component coupling reaction of pyridine, β‐keto amides, and sulfonyl chlorides yields 4‐alkenyl‐1,4‐dihydropyridines under mild conditions via sequential activation of pyridine by the sulfonyl chloride and nucleophilic addition of in situ generated acylacetonitrile.
ChemInform Abstract: Synthesis of β‐Acetoxy Alcohols by PhI(OAc)2‐Mediated Metal‐Free Diastereoselective β‐Acetoxylation of Alcohols.
Authors: Zhao Chun‐Yang , Li Liang‐Gui , Liu Qing‐Rong , Pan Cheng‐Xue , Su Gui‐Fa , Mo Dong‐Liang 
Published: November 2016

AbstractThe route from tertiary alcohols to β‐acetoxy alcohols might involve dehydration and sequential regioselective and diastereoselective dioxygenation.
ChemInform Abstract: Catalytic Oxidative Carbene Coupling of α‐Diazo Carbonyls for the Synthesis of β‐Amino Ketones via C(sp3)—H Functionalization.
Authors: Zhang Tian‐Shu , Hao Wen‐Juan , Wang Nan‐Nan , Li Guigen , Jiang Dong‐Fang , Tu Shu‐Jiang , Jiang Bo 
Published: November 2016

AbstractThe reaction of α‐diazo carbonyl compounds with N,N‐dimethylaniline derivatives and either N‐methylaniline or diverse carboxylic acids provides a broad range of α,β‐diamino ketones and α‐(acyloxy)‐β‐amino ketones.
ChemInform Abstract: Aerobic Copper‐Catalyzed Decarboxylative Thiolation.
Authors: Li Minghao , Hoover Jessica M. 
Published: November 2016

AbstractThe Cu‐catalyzed decarboxylative thiolation of aromatic and heteroaromatic carboxylic acids (I) with aryl thiols (II) is elaborated using O2 as the sole oxidant.
ChemInform Abstract: Camphor‐Based Schiff Base of 3‐Endo‐Aminoborneol (SBAB): Novel Ligand for Vanadium‐Catalyzed Asymmetric Sulfoxidation and Subsequent Kinetic Resolution.
Authors: Chuo Ting Hung , Boobala Ramalingam , Chen Chinpiao 
Published: November 2016

AbstractAmong 20 ligands prepared, endo SBAB‐14 is found to be the most efficient one.
ChemInform Abstract: Air‐Stable Triazine‐Based Ni(II) PNP Pincer Complexes as Catalysts for the Suzuki—Miyaura Cross‐Coupling.
Authors: Mastalir Matthias , Stoeger Berthold , Pittenauer Ernst , Allmaier Guenter , Kirchner Karl 
Published: November 2016

AbstractOne of the title complexes is successfully applied in the title coupling reaction of aryl boronic acids, pinacol esters and potassium phenyltrifluoroborate with aryl iodides, bromides, chlorides, tosylates, triflates, carbamates and pivaloates.
ChemInform Abstract: Spirocyclic Amino Alcohol Building Blocks Prepared via a Prins‐Type Cyclization in Aqueous Sulfuric Acid.
Authors: Lukin Alexey , Bagnyukova Darya , Kalinchenkova Natalya , Zhurilo Nikolay , Krasavin Mikhail 
Published: November 2016

AbstractThe Prins cyclization of azacycloalkanones with homoallylic alcohols is achieved in aqueous sulfuric acid providing a wide range of spirocyclic amino alcohols.
ChemInform Abstract: α,β‐Double Electrophilic Addition of Allene‐1,3‐Dicarboxylic Esters for the Construction of Polysubstituted Furans by KI/tert‐Butyl Hydroperoxide (TBHP)‐Promoted Oxidative Annulation.
Authors: Li Hong‐Liang , Wang Yu , Sun Pei‐Pei , Luo Xiaoyan , Shen Zhenlu , Deng Wei‐Ping 
Published: November 2016

AbstractThe transition metal free process renders possible the approach to various highly functionalized furan derivatives, suitable substructures in a broad field of organic chemistry.
ChemInform Abstract: Synthesis of Quaternary 3,3‐Disubstituted 2‐Oxindoles from 2‐Substituted Indole Using Selectfluor.
Authors: Jiang Xiaojian , Yang Junjie , Zhang Feng , Yu Pei , Yi Peng , Sun Yewei , Wang Yuqiang 
Published: November 2016

AbstractA number of versatile functional groups may be incorporated in the quaternary stereocenter including hydroxymethyl, aldehyde, keto and ester functionalities.
ChemInform Abstract: Synthesis of 2‐BMIDA 6,5‐Bicyclic Heterocycles by Cu(I)/Pd(0)/Cu(II) Cascade Catalysis of 2‐Iodoaniline/Phenols.
Authors: Seath Ciaran P. , Wilson Kirsty L. , Campbell Angus , Mowat Jenna M. , Watson Allan J. B. 
Published: November 2016

AbstractThe reaction of iodides (I) with alkyne (II) gives rise to indoles (III), which are readily converted into derivatives (IV), (VI), and (VIII).
ChemInform Abstract: Synthesis of Diverse Isatins via Ring Contraction of 3‐Diazoquinoline‐2,4‐diones.
Authors: Shrestha Rajeev , Lee Gun Joon , Lee Yong Rok 
Published: November 2016

AbstractThe reaction proceeds via domino Wolff rearrangement, decarboxylation, bromination, substitution, and dehydration.
ChemInform Abstract: Facile Synthesis of 3‐Aryl‐3‐hydroxy‐2‐oxindoles from 2‐Arylindoles.
Authors: Moon Hye Ran , Lee Sangku , Roh Hwa Jung , Kim Jae Nyoung 
Published: November 2016

AbstractAn efficient synthetic route to 3‐aryl‐3‐hydroxy‐2‐oxindoles is developed from 2‐arylindoles via a semipinacol type rearrangement.
ChemInform Abstract: Catalytic Enantioselective Oxa‐Hetero‐Diels—Alder Reactions of Enones with Aryltrifluoromethyl Ketones.
Authors: Zhang Dongxin , Tanaka Fujie 
Published: November 2016

AbstractThe organocatalytic oxa‐hetero‐Diels—Alder reaction of enones (I) with aryltrifluoromethyl ketones (II) leads to a mixture of racemic tetrahydropyranone (III) and enantioenriched diastereomer (IV).
ChemInform Abstract: Stereoselective Synthesis of Donor—Acceptor Cyclopropapyranone by Intramolecular Cyclopropanation of Vinylogous Carbonates: Application to the Total Synthesis of (.+‐.)‐Diospongin B.
Authors: Gharpure Santosh J. , Mane Sumit P. , Nanda Laxmi Narayan , Shukla Manoj Kumar 
Published: November 2016

AbstractThe stereo‐ and regioselective cyclopropanation of vinylogous carbonates utilizes CuI/Cu powder as a catalyst to get access to donor—acceptor substituted cyclopropapyranones.
ChemInform Abstract: Sunlight‐Promoted Cyclization versus Decarboxylation in the Reaction of Alkynoates with N‐Iodosuccinimide: Easy Access to 3‐Iodocoumarins.
Authors: Ni Shengyang , Cao Jia , Mei Haibo , Han Jianlin , Li Shuhua , Pan Yi 
Published: November 2016

AbstractThe title coumarins are obtained under sunlight via a cascade of radical iodination, spirocyclization, and ring expansion through ester migration affording the kinetically favoured product.
ChemInform Abstract: Synthesis of Diverse Catechin Congeners via Diastereoselective Intramolecular Epoxy‐Arene Cyclization.
Authors: Devi Runjun , Gogoi Dimpee , Bora Prerona , Das Sajal Kumar 
Published: November 2016

AbstractA highly stereo‐ and regioselective, metal‐free intramolecular epoxide‐arene cyclization of 2‐(phenoxymethyl)‐3‐aryloxiranes yields trans‐4‐arylchroman‐3‐ols in moderate to high yields.
ChemInform Abstract: Synthesis of Furo[3,2‐c]coumarins under Microwave Irradiation Using Nano‐CoFe2O4@SiO2—PrNH2 as an Efficient and Magnetically Reusable Catalyst.
Authors: Safaei‐Ghomi Javad , Shahbazi‐Alavi Hossein , Babaei Pouria , Basharnavaz Hadi , Pyne Stephen G. , Willis Anthony C. 
Published: November 2016

AbstractThe catalyst can be recycled and reused for six times with only a minimal loss of activity.
ChemInform Abstract: Synthesis of Pyrrolo[1,2‐a]quinolines and Ullazines by Visible Light Mediated One‐ and Twofold Annulation of N‐Arylpyrroles with Arylalkynes.
Authors: Das Amrita , Ghosh Indrajit , Koenig Burkhard 
Published: November 2016

AbstractThe annulation of N‐(2‐bromophenyl)pyrroles (I) with arylalkynes (II) gives rise to desired pyrrolo[1,2‐a]quinolines (III).
ChemInform Abstract: Facile Synthesis of Fully Decorated Imidazo[4,5‐b] and Imidazo[4,5‐c] Pyridines in Aqueous DMF via C—H Activation under Microwave Irradiation.
Authors: Avinesh Mr. P. , Jaison Mr. Thadathil J. , Sajith Ayyiliath M. , Nagaswarupa H. P. , Muralidharan A. 
Published: November 2016

AbstractThe regioisomeric access to the potential pharmacophores becomes possible in the presence of aromatic boronic acids or potassium trifluoroborates.
ChemInform Abstract: Diastereoselective Synthesis of Highly Functionalized Polycyclic Benzosultams via Tandem Cyclisations of Cyclic N‐Sulfonylimines with in situ Generated Huisgen 1,4‐Dipoles
Authors: Zhao Hong‐Wu , Chen Xiao‐Qin , Pang Hai‐Liang , Tian Ting , Li Bo , Song Xiu‐Qing , Meng Wei , Yang Zhao , Zhao Yu‐Di , Liu Yue‐Yang 
Published: November 2016

Abstract30 examples
ChemInform Abstract: Intramolecular Imidoylative Heck Reaction: Synthesis of Cyclic Ketoimines from Functionalized Isocyanide.
Authors: Wang Jian , Tang Shi , Zhu Qiang 
Published: November 2016

AbstractThe title reaction offers an efficient access to five‐ to seven‐membered cyclic ketoimines, including a symmetrical bis‐azepine.
ChemInform Abstract: Chiral Broensted Acid Catalyzed Enantioselective Phosphonylation of Allylamine via Oxidative Dehydrogenation Coupling.
Authors: Cheng Ming‐Xing , Ma Ran‐Song , Yang Qiang , Yang Shang‐Dong 
Published: November 2016

AbstractThe procedure is successfully applied to the highly enantioselective transformation of aryl substituted allylamines.
ChemInform Abstract: Ru(II)‐Catalyzed Direct C(sp2)—H Activation/Selenylation of Arenes with Selenyl Chlorides.
Authors: Shu Shiqi , Fan Zhoulong , Yao Qizheng , Zhang Ao 
Published: November 2016

AbstractA number of N‐heterocycles have been tested as directing group in the novel Ru‐catalyzed regioselective ortho‐selenylation of benzene featuring 2‐pyridinyl and 1‐pyrazolyl groups as most promising candidates that have been further examined in a broad variety of arenes.
ChemInform Abstract: Orthogonally Protected Schoellkopf′s Bis‐Lactim Ethers for the Asymmetric Synthesis of α‐Amino Acid Derivatives and Dipeptide Esters.
Authors: Hutchby Marc , Sedgwick Adam C. , Bull Steven D. 
Published: November 2016

AbstractA diastereoselective trans‐alkylation of aza‐enolates of orthogonally protected chiral bis‐lactim ethers with electrophiles, such as alkyl halides, and subsequent deprotection via hydrolysis/hydrogenation leads to dipeptide ester derivatives.
ChemInform Abstract: Phlefargesiine A, a C16N2 Lycopodium Alkaloid with an Unprecedented [6/7/6/6]‐Tetracyclic Skeleton from Phlegmariurus fargesii.
Authors: Meng Wei‐Jia , Xiong Juan , Wang Wen‐Xuan , Zhang Hai‐Yan , Zeng Huaqiang , Hu Jin‐Feng 
Published: November 2016

AbstractThe novel C16N2 Lycopodium alkaloid, phlefargesiine A (I), isolated from the whole plant of the club moss Phlegmariurus fargesii shows week inhibitory effect against acetylcholinesterase.
ChemInform Abstract: Total Synthesis of δ‐Sanshool and Analogues Thereof.
Authors: Mugnaini Claudia , Corelli Federico 
Published: November 2016

AbstractBased on a protected 1,4‐butanediol‐derived core fragment, two synthetic approaches for the total synthesis of δ‐sanshool (I) and for the preparation of small libraries of analogs are presented.