bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contact precautions for MRSA and VRE: where are we now? A survey of the Society for Healthcare Epidemiology of America Research Network
Authors: Martin Elise , Morgan Daniel J. , Pryor Rachel , Bearman Gonzalo 
Published: September 2024

Abstract

Objective:
Contact precautions for methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE) have limited data on efficacy and have been associated with patient harm. Still, a 2015 Society for Healthcare Epidemiology of America (SHEA) Research Network (SRN) survey showed only 7% of hospitals discontinued routine MRSA/VRE contact precautions. The study objectives were to identify the current proportion of hospitals that have discontinued routine MRSA/VRE contact precautions and motivations for change.

Design:
An online survey was conducted of the SRN on current use and views of contact precautions for MRSA/VRE in each facility. An initial survey followed by 2 reminders was sent between 5/18/2021 and 6/9/2021.

Participants:
SRN facilities.

Results:
The response rate was 43% (37/87) of facilities surveyed and 35% of respondents were not routinely using contact precautions for MRSA and VRE. The most frequently reported reason for discontinuing contact precautions was research on the safety of discontinuing contact precautions without an increase in healthcare-associated infections (reported for 92% of facilities for MRSA and 100% for VRE). Of those using contact precautions, the most frequently reported reason to continue was a lack of safety data for discontinuation (MRSA 58% and VRE 46%). Most of those continuing contact precautions were interested in using contact precautions differently in their facility (MRSA 63% and VRE 58%).

Conclusions:
Over one in three healthcare facilities surveyed do not use contact precautions for MRSA or VRE. Most facilities choosing to continue contact precautions are interested in a different implementation strategy.
Community partner coauthorship for increased implementation science impact: Strengthening capacity and engagement
Authors: Lee Rebekka M. , Torres Cristina Huebner , Daly James G. , Thomas Annette , Hannon Peggy A. , Likumahuwa-Ackman Sonja , Emmons Karen M. 
Published: September 2024

Abstract
Engaging diverse partners in each phase of the research process is the gold standard of community-engaged research and adds value to the impact of implementation science. However, partner engagement in dissemination, particularly meaningful involvement in developing peer-reviewed manuscripts, is lacking. The Implementation Science Centers in Cancer Control are using the Translational Science Benefits Model to demonstrate the impact of our work beyond traditional metrics, including building capacity and promoting community engagement. This paper presents a case example of one center that has developed a policy for including community partners as coauthors. Standard practices are used to foster clear communications and bidirectional collaboration. Of published papers focused on center infrastructure and implementation research pilots, 92% have community partner coauthors. This includes 21 individuals in roles ranging from physician assistant to medical director to quality manager. Through this intentional experience of co-creation, community partners have strengthened implementation science expertise. Community coauthors have also ensured that data interpretation and dissemination reflect real-world practice environments and offer sustainable strategies for rapid translation to practice improvements. Funders, academic journals, and researchers all have important roles to play in supporting community coauthors as critical thought partners who can help to narrow the gap between research and practice.
A Nature-based Social Prescribing Impact Pathways Framework (NabSPIP): applying the One Health perspective
Authors: Kenyon Anna V. 
Published: September 2024

Abstract
The need for a planetary approach to healthcare is widely recognised at national and international levels. Social prescribing is becoming an increasingly popular strategy for meeting contemporary social, physical and mental health needs as well as tackling health inequalities. As this is a relatively new and emerging healthcare intervention, a comprehensive and accurate understanding of its impact is essential to support continued improvements in care, develop strategies for scale-up and delivery and justify further funding and investment. Nature-based Social Prescribing (NBSP) has unique potential to affect animal and environmental outcomes as well as human health. The One Health perspective can be used to operationalise and evaluate NBSP. This article presents the Nature-based Social Prescribing Impact Pathways (NaBSPIP) framework, which can be used to guide NBSP design and evaluation to leverage maximum benefit for humans, animals and the environment that we share.
The Temperate North Pacific Bryozoan Smittoidea prolifica (Cheilostomatida: Smittinidae) in the Northwest Atlantic
Authors: Trott Thomas J. 
Published: September 2024

Abstract
The Pacific bryozoan, Smittoidea prolifica Osburn, 1952, is reported for the first time from the Northwest Atlantic coast. Colonies were discovered during routine benthic sampling of Casco Bay, Maine, encrusting mussel shells and barnacles. Aiming to compare specimens from native and introduced locations, uncertainties about the Pacific range of S. prolifica were resolved by re-examining specimens from Japan, southern Korea, the United States west coast, and Mexico. The occurrence of this species in Japan was confirmed but southern Korea specimens were found to be Smittoidea spinigera (Liu, 1990). Comparisons of biometrics among specimens from widely dispersed locations where S. prolifica is native and introduced showed significant trends in variation with most characters largest for California and smallest for Germany. Zooid width was largest for Maine specimens. Comparisons between oceans showed that Pacific and Atlantic specimens differed significantly in all measures except zooid length and orifice width. Low substrate specificity and broad range of temperatures and salinities in occupied habitats suggests the potential for successful introduction is high. Smittoidea prolifica was most likely introduced through commercial shipping from the North Sea where it is an established non-native species. This was the third non-indigenous species found in Casco Bay discovered within the same timeframe and which shared the same likely region of origin. This spike matched a rise in commercial shipping from the Northeast Atlantic to Portland, Maine, suggesting this seaport is shifting towards becoming a bioinvasion hotspot.
The diversity, distribution, and taxonomic history of the Brazilian Tanaidacea (Crustacea)
Authors: Segadilha Juliana L. , Araújo-Silva Catarina L. 
Published: September 2024

Abstract
Tanaidaceans have a worldwide distribution, with 36 families, 316 genera, and 1575 extant species described. This study aimed to compile the resulting taxonomic information for Brazilian waters obtained to produce the available online catalogue Taxonomic Catalogue of the Brazilian Fauna. Results show 63 species described for Brazilian waters: 30 Apseudomorpha and 33 Tanaidomorpha, distributed in 46 genera and 18 families. For apseudomorphan, Kalliapseudidae is the most diverse family (12.7%), followed by Apseudidae and Parapseudidae (9.5% each). For tanaidomorphan, Typhlotanaidae is the most diverse (15.9%) followed by Leptocheliidae (9.5%) and Tanaididae (7.9%). In Brazilian waters, more than 60% of Tanaidacea species are distributed in shallow waters (42 species; 63.6%), including continental areas, and about 1/3 are recorded from deep-sea (24 species; 36.4%). Southeast Region of Brazil holds most records with 46 occurrences, followed by the Northeast Region with 19 occurrences. Our results highlight the increasing number of publications and new Brazilian tanaids species in the last 15 years, and this is directly correlated to where specialists in alpha-taxonomy, systematics/phylogeny, and ecology are based in. Our current dataset also indicates an important aspect regarding the lack of taxonomic experts of Tanaidacea worldwide, but especially in Brazil. This study gives an overview of all the information that may help elucidate future research on the taxonomic diversity of tanaidaceans in Brazil, thus it is expected that this may encourage further studies and specialists for the group.
Configuration design of movable heavy-duty reconfigurable posture adjustment platform with dual motion modes
Authors: Wang Rui , Xiong Xiaoyan , Zhang Jinzhu , Yuan Ruilin 
Published: September 2024

AbstractThe existing single-mode posture adjustment equipment for solar wing docking is only suitable for a limited number of satellite dimensions; it could not meet the diverse development trends of satellite models. The working range requirements are different when different-sized satellites dock with the solar wing, and the docking process is divided into two stages in this paper. While the DOFs required for the two stages are different, a movable heavy-load reconfigurable redundant posture adjustment platform (RrPAP) with dual motion modes is proposed in this paper. The RrPAP consists of a wheeled mobile platform and a reconfigurable parallel posture adjustment mechanism (PAM). The micro-motion PAM limb types are synthesized, and the comprehensive load-bearing index is proposed to select the mechanism types for heavy-load conditions. A decentralized four-limb six-degree-of-freedom (6-DOF) parallel micro-motion PAM is designed. In the macro-motion stage, for the PAM to still have a defined motion after being released from ground constraints, a serial coupling sub-chain is designed between adjacent limbs to restrict relative movement between them. A type synthesis method for symmetrically coupled mechanisms based on mechanism decoupling and motion distribution is proposed. Four types of symmetrically coupled mechanisms with multi-loop consisting of serial coupling sub-chains are synthesized by using this method. The feasibility of the proposed method is demonstrated through an example using the constraint synthesis method based on screw theory. This work provides a foundation for subsequent refinement and expansion of type synthesis theories and the selection of new types of mechanisms.
The times, they are a-changing: Australian secondary classroom music teachers reflect on their early career 40 years on
Authors: Carter Jennifer 
Published: September 2024

Abstract
The period 1974–1999 were transition years for government school systems in Australia and New South Wales (NSW), where government agencies issued numerous policies and documents to influence and manage education and resultant classroom pedagogy. During those years, many music syllabi were produced for enactment in NSW, placing multiple demands on teacher accountability. This paper forms part of a larger study involving three generations of music teachers representing different career stages and experiences and presents the voices of the group of experienced music teachers (EMTs), exploring the impact of syllabus change, teacher identity, pedagogical skills, and eventual flourishing as confident teachers.
Impact trajectories of childhood maltreatment duration on affective and social development
Authors: Ardizzi Martina , Ravera Roberto , Umiltà Maria Alessandra , Ferroni Francesca , Ampollini Silvia , Kolacz Jacek , Porges Stephen , Gallese Vittorio 
Published: September 2024

Abstract
Childhood maltreatment (CM) deeply impacts victims’ social competences. The aim of the present study was to investigate the effect that CM duration exerts on victims’ affective and social development testing three different impact trajectories (i.e., linear, logarithmic and quadratic) and its physiological (facial mimicry and autonomic regulation of the heart) and behavioral (percentage of anger recognition false alarm) markers. In a cross-sectional design, 73 Sierra Leonean youths (all males, 5–17 years old) were enrolled in the study. Of those, 36 were homeless all abandoned at the age of 4 and exposed to CM, whereas 37 were controls. Only physiological markers of affective development were influenced by CM duration. A quadratic relation between the autonomic regulation recorded at rest and CM duration was found, indicating initial physiological compensation followed by progressive autonomic withdrawal. Furthermore, CM duration was associated to a specific linear decrease of facial mimicry and vagal regulation in response to angry and sad facial expressions whereas no influences were detected for happy and fearful faces. The results of the present study provide insightful clues on victims’ natural patterns of resilience, deterioration, and chronicity, allowing a deeper comprehension of the developmental pathways through which early life adversities place youths on a track of lifelong health disparities.
From prenatal maternal anxiety and respiratory sinus arrhythmia to toddler internalizing problems: The role of infant negative affectivity
Authors: Zhou Anna M. , Gao Mengyu (Miranda) , Ostlund Brendan , Maylott Sarah E. , Molina Nicolette C. , Bruce Madeleine , Raby K. Lee , Conradt Elisabeth , Crowell Sheila E. 
Published: September 2024

Abstract
Prenatal maternal anxiety is considered a risk factor for the development of child internalizing problems. However, little is known about potential mechanisms that account for these associations. The current study examined whether prenatal maternal anxiety was indirectly associated with toddler internalizing problems via prenatal maternal physiology and infant negative affectivity. We examined these associations in a longitudinal study of 162 expectant mothers from their third trimester until 18 months postpartum. Path analyses showed that higher prenatal anxiety was associated with higher infant negative affectivity at 7 months, which in turn was associated with higher toddler internalizing problems at 18 months. Prenatal anxiety was not indirectly associated with child outcomes via baseline or task-evoked respiratory sinus arrhythmia (RSA) in response to an infant cry while pregnant. However, pregnant women with greater decreases in task-evoked RSA had toddlers with greater internalizing problems, which was mediated by infant negative affectivity at 7 months. Findings suggest that prenatal anxiety and RSA reactivity to an infant cry may be independent risk factors for the development of infant negative affectivity, which in turn increases risk for toddler internalizing problems. These findings contribute to a growing literature on mechanisms that underlie intergenerational transmission of internalizing problems.
Pharmacoeconomic implications of preference toward reference- versus generic-brand antidepressants in primary care
Authors: Gultekin Onur , Aydin Volkan , Bayram Dilara , Atac Omer , Akici Ahmet 
Published: September 2024

Abstract

Background:
The prevalence of depression is gradually increasing worldwide with an increasing utilization of antidepressants. Nevertheless, despite their lower costs, generic-brand antidepressants were reported to be less prescribed. We aimed to examine the costs of reference- versus generic-brand antidepressant prescriptions in primary care practice.

Methods:
This cross-sectional study included electronic prescriptions for adult patients that contained antidepressants (World Health Organization’s Anatomical Therapeutic Chemical (ATC) code: N06A), which were generated by a systematically selected sample of primary care doctors (n = 1431) in Istanbul in 2016. We examined the drug groups preferred, the reference- versus generic-brand status, and pharmacotherapy costs.

Findings:
The majority of the prescriptions were prescribed for women (71.8%), and the average age of the patients was 53.6 ± 16.2 years. In prescriptions with a depression-related indication (n = 40 497), the mean number and cost of drugs were 1.5 ± 1.0 and 22.7 ± 26.4 United States Dollar ($) per prescription, respectively. In these prescriptions, the mean number and cost of antidepressants per encounter were 1.1 ± 0.2 and $17.0 ± 13.2, respectively. Reference-brand antidepressants were preferred in 58.2% of depression-related prescriptions, where the mean cost per prescription was $18.3 ± 12.4. The mean cost per prescription of the generics, which constituted 41.8% of the antidepressants in prescriptions, was $15.1 ± 11.4. We found that if the generic version with the lowest cost was prescribed instead of the reference-brand, the mean cost per prescription would be $12.9 ± 11.2.

Conclusions:
Our study highlighted the substantial pharmacoeconomic impact of generic-brand antidepressant prescribing, whose preference over reference-brands could reduce the cost of antidepressant medication treatment by 17.5% in primary care, which could be approximately doubled if the cheapest generic antidepressant had been prescribed.
Overall review of distributed photovoltaic development in China: process, dynamic, and theories
Authors: Hongliang Zhang Alex , Sirin Selahattin Murat 
Published: September 2024

Abstract

Non-technical summary
DPV systems, typically small to medium-sized solar power installations on buildings, which primarily and directly supply electricity to industrial, commercial, or residential consumers in proximity. DPV is an advocated renewable substation for climate change and energy saving for merits of low installation costs, high energy efficiency, and the ability to provide decentralized power supply. Our research has theoretical significance in explaining and understanding the development and policy evolution of DPV in China and provide valuable suggestions for future industry policies during grid parity.

Technical summary
Since 2021, China has been phasing out its decade-long feed-in tariff policies, reducing the photovoltaic industry's dependency on subsidies. Despite the challenges posed by declining electricity prices and slowdown in economic growth, the authorities continue to prioritize the development of DPV due to its low investment costs, high energy efficiency, and decentralized power supply, and these technologies have already achieved demand-side parity. Driven by this phenomenon, this study examines the trajectory of DPV diffusion and the evolution of related policies over the last decade. It unravels the dynamic mechanism of DPV investment through theoretical analysis and develops a macro model to identify optimal installation strategies and renewable energy proportions. Our findings highlight the increasing role of green energy and suggest that green finance is crucial for stimulating DPV investment in the era of grid parity. The study concludes with practical recommendations for overcoming DPV challenges in China.

Social media summary
DPV has become a prominent renewable energy solution in other countries but not in China. We probe the system dynamics modeling to give explanation and solution during grid parity.
Mcl-1 expression is a predictive marker of response to gemcitabine plus nab-paclitaxel for metastatic pancreatic cancer
Authors: Urabe Makiko , Ikezawa Kenji , Seiki Yusuke , Watsuji Ko , Kawamoto Yasuharu , Hirao Takeru , Kai Yugo , Takada Ryoji , Yamai Takuo , Mukai Kaori , Nakabori Tasuku , Uehara Hiroyuki , Nagata Shigenori , Ohkawa Kazuyoshi 
Published: September 2024

AbstractAntiapoptotic protein, including Mcl-1, expression is frequently observed in pancreatic cancer. Gemcitabine plus nabpaclitaxel (GnP) is the standard chemotherapy for metastatic pancreatic cancer (MPC); however, predictive markers for its efficacy remain unestablished. This study evaluated the association between GnP’s therapeutic effects and Mcl-1 expression in tissue samples obtained using endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for pancreatic tumor or percutaneous ultrasound-guided biopsy for metastatic liver tumor. We retrospectively reviewed 38 patients with histologically diagnosed MPC who received GnP as the first-line chemotherapy at our institute between December 2014 and July 2018. Post-immunohistochemistry analysis for Mcl-1 expression detection, patients were divided to into two groups based on the cell proportion showing Mcl-1 immunoreactivity: positive (> 20%; 23 [60.5%] patients) and negative (≤ 20%; 15 [39.5%] patients) groups. Clinical characteristics did not differ between the two groups. The Mcl-1 positive group showed a significantly higher disease control rate (95.7% vs. 73.3%; P = 0.046), longer progressionfree survival (PFS) (7.2 months vs. 4.9 months; P = 0.018) and longer overall survival (OS) (14.9 months vs. 9.2 months; P = 0.008) than the Mcl-1 negative group. Multivariate analysis showed that Mcl-1 expression was an independent predictive marker for PFS and OS. Mcl-1 expression could be a predictive marker for favorable response to GnP.
In vitro comparison of human and murine trabecular meshwork cells: implications for glaucoma research
Authors: Langer Fridolin , Binter Maximilian , Hu Xiaonan , Hufendiek Karsten , Meister Roland , Tode Jan , Framme Carsten , Fuchs Heiko 
Published: September 2024

AbstractThe trabecular meshwork (TM) is crucial for regulating intraocular pressure (IOP), and its dysfunction significantly contributes to glaucoma, a leading cause of vision loss and blindness worldwide. Although rodents are commonly used as animal models in glaucoma research, the applicability of these findings to humans is limited due to the insufficient understanding of murine TM. This study aimed to compare primary human TM (hTM) and murine TM (mTM) cells in vitro to enhance the robustness and translatability of murine glaucoma models. In this in vitro study, we compared primary hTM and mTM cells under simulated physiological and pathological conditions by exposing both cell types to the glucocorticoid dexamethasone (DEX) and Transforming Growth Factor β (TGFB2), both of which are critical in the pathogenesis of several ophthalmological diseases, including glaucoma. Phagocytic properties were assessed using microbeads. Cells were analyzed through immunocytochemistry (ICC) and Western blot (WB) to evaluate the expression of extracellular matrix (ECM) components, such as Fibronectin 1 (FN1) and Collagen IV (COL IV). Filamentous-Actin (F-Act) staining was used to analyze cross-linked actin network (CLAN) formation. Additionally, we evaluated cytoskeletal components, including Vimentin (VIM), Myocilin (MYOC), and Actin-alpha-2 (ACTA2). Our results demonstrated significant similarities between human and murine TM cells in basic morphology, phagocytic properties, and ECM and cytoskeletal component expression under both homeostatic and pathological conditions in vitro. Both human and murine TM cells exhibited epithelial-to-mesenchymal transition (EMT) after exposure to DEX or TGFB2, with comparable CLAN formation observed in both species. However, there were significant differences in FN1 and MYOC induction between human and murine TM cells. Additionally, MYOC expression in hTM cells depended on fibronectin coating. Our study suggests that murine glaucoma models are potentially translatable to human TM. The observed similarities in ECM and cytoskeletal component expression and the comparable EMT response and CLAN formation support the utility of murine models in glaucoma research. The differences in FN1 and MYOC expression between hTM and mTM warrant further investigation due to their potential impact on TM properties. Overall, this study provides valuable insights into the species-specific characteristics of TM and highlights opportunities to refine murine models for better relevance to human glaucoma.