bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salvage Therapy or Simplification of Salvage Regimens with Dolutegravir plus Ritonavir-Boosted Darunavir Dual Therapy in Highly cART-Experienced Subjects: An Italian Cohort
Authors: Capetti Amedeo F , Sterrantino Gaetana , Cossu Maria V , Cenderello Giovanni , Cattelan Anna M , Socio Giuseppe V De , Rusconi Stefano , Riccardi Niccolò , Baldin Gian M , Cima Serena , Niero Fosca P , Rizzardini Giuliano , Sasset Lolita 
Published: September 2016

Background Dolutegravir plus darunavir provide a high genetic barrier to HIV-1 resistance and are suitable for simple salvage regimens. Methods All HIV-1-infected subjects treated with dolutegravir plus boosted darunavir dual therapy between March 2011 and September 2015 were included in an observational cohort. Data were collected at baseline and at weeks 4, 12, 24 and 48. Results We enrolled 113 subjects. After week 24, one was lost at follow-up, one dropped out for grade 2 elevation of liver enzymes, one died from illicit drug abuse and one from cancer-related sepsis. The mean age was 51, 26.5% were female and 9.7% were non-Caucasian. Twenty had never experienced failure. A total of 99 had reverse-transcriptase (RT) mutations, 87 had protease inhibitor mutations and 12 had integrase strand transfer inhibitor (INSTI) mutations. Viraemic patients declined from baseline to week 24 from 43.4% to 6.2%, the remainder being due to high baseline viraemia or adherence issues. The proportion of subjects with viraemia 1–49 copies/ml remained at 20.4% while those in whom no virus was detected (NVD) increased from 36.3% to 73.5% by week 24. All the 47 subjects who had a 48-week follow-up had <50 copies/ml and 42 (89.4%) had NVD. 18 subjects had reduced sensitivity to darunavir (Stanford median score 15, range 15–40), but none rebounded, 6 having a 24-week and 7 a 48-week follow-up. The median variation in serum creatinine was -0.01 (range +0.2 to -0.21) mg/dl. Conclusions This dual regimen provides a simple salvage regimen and proved safe and effective in this cohort.
Active Season Microhabitat and Vegetation Selection by Giant Gartersnakes Associated with a Restored Marsh in California
Authors: Halstead Brian J. , Valcarcel Patricia , Wylie Glenn D. , Coates Peter S. , Casazza Michael L. , Rosenberg Daniel K. 
Published: September 2016

Abstract
Studies of habitat selection can reveal important patterns to guide habitat restoration and management for species of conservation concern. Giant gartersnakes Thamnophis gigas are endemic to the Central Valley of California, where &gt;90% of their historical wetland habitat has been converted to agricultural and other uses. Information about the selection of habitats by individual giant gartersnakes would guide habitat restoration by indicating which habitat features and vegetation types are likely to be selected by these rare snakes. We examined activity patterns and selection of microhabitats and vegetation types by adult female giant gartersnakes with radiotelemetry at a site composed of rice agriculture and restored wetlands using a paired case-control study design. Adult female giant gartersnakes were 14.7 (95% credible interval [CRI] = 9.4–23.7) times more likely to be active (foraging, mating, or moving) when located in aquatic habitats than when located in terrestrial habitats. Microhabitats associated with cover—particularly emergent vegetation, terrestrial vegetation, and litter—were positively selected by giant gartersnakes. Individual giant gartersnakes varied greatly in their selection of rice and rock habitats, but varied little in their selection of open water. Tules Schoenoplectus acutus were the most strongly selected vegetation type, and duckweed Lemna spp., water-primrose Ludwigia spp., forbs, and grasses also were positively selected at the levels of availability observed at our study site. Management practices that promote the interface of water with emergent aquatic and herbaceous terrestrial vegetation will likely benefit giant gartersnakes. Given their strong selection of tules, restoration of native tule marshes will likely provide the greatest benefit to these threatened aquatic snakes.
Growth, Food Consumption, and Energy Status of Juvenile Pallid Sturgeon Fed Natural or Artificial Diets
Authors: Meyer Hilary A. , Chipps Steven R. , Graeb Brian D.S. , Klumb Robert A. 
Published: September 2016

Abstract
Stocking of hatchery-raised fish is an important part of the pallid sturgeon Scaphirhynchus albus recovery program. In the wild, juvenile pallid sturgeon consume primarily aquatic insects, although little is known about specific dietary needs. In hatchery settings, pallid sturgeon are fed commercial diets that are formulated for salmonids. To compare food consumption, growth, and energy status of pallid sturgeon fed artificial or natural diets, we conducted a laboratory study using 24 juvenile pallid sturgeon (initial fork length 153–236 mm). Pallid sturgeon were fed a daily ration of either commercial pellets (1 mm, slow sinking; 45% protein, 19% fat) or chironomid larvae for 5 wk. Natural-fed pallid sturgeon exhibited a greater specific growth rate (2.12% d−1) than pellet-fed fish (0.06% d−1). Similarly, relative condition was greater for natural-fed sturgeon (Kn = 1.11) than that observed for pellet-fed fish (Kn = 0.87). In contrast, the hepatosomatic index was significantly higher in pellet-fed fish (2.5%), indicating a high lipid diet compared with natural-fed sturgeon (1.4%). Given the importance of natural diets to fish digestion and growth, it is suggested that a more holistic approach be applied in the development of a practical diet for pallid sturgeon that incorporates attributes of natural prey.
L’interro-négative à l’oral en anglais contemporain : enjeux argumentatifs et pragmatiques
Authors: Levillain Pauline 
Published: September 2016

Cet article a pour objectif d’ouvrir de nouvelles perspectives sur l’analyse de l’interro-négative en anglais oral américain en considérant non seulement ses enjeux argumentatifs mais aussi pragmatiques au sein d’un « discours-en-interaction » (Catherine Kerbrat-Orecchioni, 2005). Nous faisons apparaître que la proposition interro-négative n’est pas l’équivalente négative d’une interrogative « classique », positive : son étude permet en effet de saisir la composante argumentative inhérente à la relation interlocutive.Pour ce faire, les occurrences d’interro-négatives sont analysées à partir de conversations du Santa Barbara Corpus of Spoken American English et examinées selon deux axes, celui de l’émetteur et celui du récepteur. Ces enjeux sont d’abord exprimés en des termes argumentatifs, en exposant notamment les points de vue que ce type de proposition permet d’exprimer. Ensuite, ces formes ne devant pas être interprétées littéralement, un éclairage pragmatique met au jour les actes de langage indirects qu’une telle proposition permet d’accomplir, en faisant référence à John R. Searle (1979). Enfin, les stratégies discursives à l’œuvre dans les extraits, notamment la négociation de points de vue, sont considérées à la lumière de la théorie de la relation interlocutive de Catherine Douay (2000). L’interprétation de telles formes faisant appel à la récupération de données linguistiques et extra-linguistiques, explicites et implicites, nécessaires à la reconstruction du « vrai » message, l’interlocuteur se voit attribuer le rôle de « coauteur » (Douay, 2000) de message.
Spinal-Exercise Prescription in Sport: Classifying Physical Training and Rehabilitation by Intention and Outcome
Authors: Spencer Simon , Wolf Alex , Rushton Alison 
Published: September 2016

Context:Identification of strategies to prevent spinal injury, optimize rehabilitation, and enhance performance is a priority for practitioners. Different exercises produce different effects on neuromuscular performance. Clarity of the purpose of a prescribed exercise is central to a successful outcome. Spinal exercises need to be classified according to the objective of the exercise and planned physical outcome.Objective:To define the modifiable spinal abilities that underpin optimal function during skilled athletic performance, clarify the effect of spinal pain and pathologic conditions, and classify spinal exercises according to the objective of the exercise and intended physical outcomes to inform training and rehabilitation.Design:Qualitative study.Data Collection and Analysis:We conducted a qualitative consensus method of 4 iterative phases. An exploratory panel carried out an extended review of the English-language literature using CINAHL, EMBASE, MEDLINE, and PubMed to identify key themes and subthemes to inform the definitions of exercise categories, physical abilities, and physical outcomes. An expert project group reviewed panel findings. A draft classification was discussed with physiotherapists (n = 49) and international experts. Lead physiotherapy and strength and conditioning teams (n = 17) reviewed a revised classification. Consensus was defined as unanimous agreement.Results:After the literature review and subsequent analysis, we defined spinal abilities in 4 categories: mobility, motor control, work capacity, and strength. Exercises were subclassified by functionality as nonfunctional or functional and by spinal displacement as either static (neutral spinal posture with no segmental displacement) or dynamic (dynamic segmental movement). The proposed terminology and classification support commonality of language for practitioners.Conclusions:The spinal-exercise classification will support clinical reasoning through a framework of spinal-exercise objectives that clearly define the nature of the exercise prescription required to deliver intended physical outcomes.
Dialogic education for and from authorial agency
Authors: Matusov Eugene , Smith Mark , Soslau Elizabeth , Marjanovic-Shane Ana , Von Duyke Katherine 
Published: September 2016

In this paper, we extend Bakhtin's ethical philosophical ideas to education and introduce a dialogic authorial agency espoused approach. We then consider this approach in opposition to the mainstream technological espoused approach, while focusing our contrasting analysis on student’s authorial agency and critical dialogue. We argue that the technological approach assumes that the "skills" or "knowledge" are garnered in pursuit of preset curricular endpoints (i.e., curricular standards). Since the goals of the technological approach are divorced from the students’ personal goals, values, and interests, they are incompatible and irreconcilable with what we idealize as the true goal of education, education for agency. The authorial agency approach to education (Dialogic Education For and From Authorial Agency) emphasizes the unpredictable, improvisational, eventful, dialogic, personal, relational, transcending, and ontological nature of education. The authorial agency of the student and of the teacher are valued and recognized by all participants as the primary goal of education – supported by the school system and broader society. The approach defines education as a learner’s leisurely pursuit of critical examination of the self, the life, and the world in critical dialogue. The purpose of authorial agency pedagogy is to facilitate this process by promoting students’ agency and unique critical voices in socially desired practices – critical voices, recognized by the students themselves and others relevant to the particular practice(s). Ultimately, in the authorial education for and from authorial agency, students are led into investigating and testing their ideas and desires, assuming new responsibilities and developing new questions and concerns. Finally, we describe and analyze the first author’s partially successful and partially failing attempt to enact a dialogic authorial approach. It will allow the reader to both visualize and problematize a dialogic authorial approach. We will consider a case with a rich “e-paper trail” written by 11 undergraduate, pre-service teacher education students (mostly sophomores), and the instructor (Peter, the first author, pseudonym) in a course on cultural diversity. The case focuses on the university students (future teachers) and their professor discussing several occasions that involved interactions between Peter and one minority child in an afterschool center. Our research questions in this empirical study were aimed at determining the successes, challenges, and failures of the dialogic authorial pedagogical approach and conditions for them
Het UBO-register
Authors: van Roomen T.R. 
Published: September 2016

Het UBO-register. Achtergrond en stand van zaken
In de vierde Europese anti-witwasrichtlijn wordt aan lidstaten de verplichting opgelegd om een centraal register in te stellen met informatie over de uiteindelijk begunstigden van vennootschappen en andere juridische entiteiten – het zogenaamde UBO-register. Inmiddels heeft de minister van Financiën de contouren gepresenteerd van het Nederlandse UBO-register. Dit artikel bevat een overzicht van de achtergrond en stand van zaken.
Noot bij Rb. Amsterdam 9 maart 2016, ECLI:NL:RBAMS:2016:1199
Authors: Nan J.S. 
Published: September 2016

Noot bij Rb Amsterdam 9 maart 2016, ECLI:NL:RBAMS:2016:1199
De rechtbank acht artikel 3 sub a Regeling wapens en munitie te vaag, onder meer omdat voor de burger niet duidelijk is wanneer een (luchtdruk)wapen een sprekende gelijkenis vertoont met een echt wapen. De annotator meent dat dat oordeel rechtens onjuist is en dat de motivering van de gegeven vrijspraak de eerste drie vragen van artikel 350 Sv door elkaar haalt.
Artificial Chemistries
Authors: Banzhaf Wolfgang , Yamamoto Lidia 
Published: September 2016

An introduction to the fundamental concepts of the emerging field of Artificial Chemistries, covering both theory and practical applications.
The field of Artificial Life (ALife) is now firmly established in the scientific world, but it has yet to achieve one of its original goals: an understanding of the emergence of life on Earth. The new field of Artificial Chemistries draws from chemistry, biology, computer science, mathematics, and other disciplines to work toward that goal. For if, as it has been argued, life emerged from primitive, prebiotic forms of self-organization, then studying models of chemical reaction systems could bring ALife closer to understanding the origins of life. In Artificial Chemistries (ACs), the emphasis is on creating new interactions rather than new materials. The results can be found both in the virtual world, in certain multiagent systems, and in the physical world, in new (artificial) reaction systems. This book offers an introduction to the fundamental concepts of ACs, covering both theory and practical applications.
After a general overview of the field and its methodology, the book reviews important aspects of biology, including basic mechanisms of evolution; discusses examples of ACs drawn from the literature; considers fundamental questions of how order can emerge, emphasizing the concept of chemical organization (a closed and self-maintaining set of chemicals); and surveys a range of applications, which include computing, systems modeling in biology, and synthetic life. An appendix provides a Python toolkit for implementing ACs.
Solution-based mist CVD technique for CH3NH3Pb(Br1−
xClx)3 inorganic–organic perovskites
Authors: Nishinaka Hiroyuki , Yoshimoto Masahiro 
Published: September 2016

Abstract
We report the growth of inorganic–organic perovskites using a solution-based mist chemical vapor deposition (mist CVD) technique and the successful growth of the alloying CH3NH3Pb(Br1−

x
Cl
x
)3 using mixture solutions of Br and Cl precursors. The formation mechanism of the inorganic–organic perovskite grown by the laminar flow-type mist CVD is suggested to be a vapor phase reaction, although solution precursors are used. The near-band-edge emissions from photoluminescence can be tuned from 500 to 550 nm by considering Br/Cl ratios in the solution without crystal phase segregation by incorporating Cl into crystalline CH3NH3PbBr3 films.
Fully printed and flexible ferroelectric capacitors based on a ferroelectric polymer for pressure detection
Authors: Sekine Tomohito , Sugano Ryo , Tashiro Tomoya , Fukuda Kenjiro , Kumaki Daisuke , Dos Santos Fabrice Domingues , Miyabo Atsushi , Tokito Shizuo 
Published: September 2016

Abstract
We report on the fabrication and demonstration of fully printed ferroelectric capacitors using poly(vinylidene fluoridetrifluoroethylene) [P(VDF–TrFE)]. The printed ferroelectric capacitors were primarily fabricated by ink-jet printing on a thin plastic film substrate. The annealing process for the P(VDF–TrFE) layer was optimized from the viewpoints of surface morphology and crystallinity. A good ferroelectric polarization–electric field loop and piezoelectricity in the P(VDF–TrFE) were achieved for the printed ferroelectric capacitors. We have succeeded in the detection of a weak pressure of 150 mbar using the printed ferroelectric capacitor, which is an indication of a potential application to health-care biosensors. These results were realized by the optimization of the annealing temperature for the P(VDF–TrFE) layer.
Quantifying the probability of meteotsunami occurrence from synoptic atmospheric patterns
Authors: Šepić Jadranka , Vilibić Ivica , Monserrat Sebastian 
Published: September 2016

AbstractA synoptic atmospheric index is constructed for the region of the Balearic Islands, Spain. The index links the occurrence of meteotsunamis, i.e., atmospherically induced high‐frequency sea level oscillations (2 min < T < 120 min), to contemporaneous meteorological synoptic conditions above the region. The correlation between the synoptic index and wave heights is found to be significant and high (up to 0.75). The vertical wind profile is recognized as the most important variable governing the sea level response to atmospheric conditions. The probability of the occurrence of a meteotsunami can be then evaluated from synoptic atmospheric variables. The results show that there exists an index threshold, below which the probability for an intense meteotsunami occurrence is extremely low. However, meteotsunami‐favorable synoptic conditions (the index exceeding the threshold value) are crucial but insufficient; some mesoscale features, not reflected in the synoptic pattern, are found to play an important role in meteotsunami generation. The constructed index is potentially applicable to other world locations where a set of tsunamigenic synoptic conditions may be defined in a similar way as at the Balearic Islands. The index can be used to estimate the rate of meteotsunami occurrence under the conditions of past, present, and future climates. It can also be effectively used in meteotsunami warning systems, especially to switch between a “silent mode” (index below the threshold value) to an “event mode.”
Universal time variations of the auroral hemispheric power and their interhemispheric asymmetry from TIMED/GUVI observations
Authors: Luan Xiaoli , Wang Wenbin , Burns Alan , Dou Xiankang 
Published: September 2016

AbstractThis paper quantitatively analyzes the auroral hemispheric power (HP) and its interhemispheric asymmetry as a function of universal time (UT) for geomagnetically quiet conditions (Kp 1–3) from Thermosphere Ionosphere Mesosphere Energetics and Dynamics/Global Ultraviolet Imager (TIMED/GUVI) imaging observations. The HP variation with UT can be approximately characterized as two cases: One is for similar HP variations in the equinoxes in the Northern Hemisphere and for the June solstices of both hemispheres, and the other is for similar HP patterns in the equinoxes in the Southern Hemisphere and for the December solstices of both hemispheres. In the equinoxes, the HP variations are interhemispherically asymmetric due to different occurrence time of the HP peak. In the solstices, the HP is generally interhemispherically symmetric in its diurnal variations, but there is interhemispheric asymmetry in the magnitudes of the maximum HP. For geomagnetically quiet conditions (Kp = 2), in the equinoxes relative interhemispheric differences are typically between 0 and 20%, with respect to the averaged HP from the two hemispheres, while during the solstices, the maximum relative interhemispheric asymmetry can be as large as 30% in December, but it is only ~15% in June. These two cases are mainly associated with variations of auroral precipitation power in the night side sector (21:00–03:00 magnetic local time/MLT), which are primarily controlled by solar illumination conditions in both hemispheres and are also attributed to the difference in the geographical area of the auroral oval in the two hemispheres. Furthermore, the general interhemispheric symmetry of the HP variations in solstices suggests that auroral acceleration is not only controlled locally by solar illumination conditions, which has been well known previously, but also might be affected by processes in the precipitation source region.
Equatorial noise emissions with a quasiperiodic modulation observed by DEMETER at harmonics of the O+ ion gyrofrequency
Authors: Parrot Michel , Nĕmec František , Santolík Ondřej , Cornilleau‐Wehrlin Nicole 
Published: September 2016

AbstractThe analysis of ionospheric equatorial noise (EN) with a quasiperiodic (QP) modulation observed by the Detection of Electro‐Magnetic Emissions Transmitted from Earthquake Regions (DEMETER) spacecraft is presented. These EN emissions, also called whistler mode or fast magnetosonic waves, play an important role in acceleration of radiation belt electrons. A statistical analysis with 103 events shows that they occur just after intense magnetic storms. Usually, they are generated by unstable proton ring distribution close to the magnetic equator at harmonics of the proton gyrofrequency in the inner magnetosphere (2 < L < 8). But at lower L values down in the ionosphere three events have been analyzed and it appears that the EN waves are at harmonics of—or very close to—a O+ ion gyrofrequency which can be found close to or slightly above the satellite. The wave propagation analysis indicates that these emissions are coming from an area above the satellite. Concerning one event, the EN emissions are observed on several consecutive orbits and there is a temporal coincidence with observations performed by the Cluster satellites at higher altitudes in the magnetosphere. EN emissions at lower frequencies have been also observed by the Cluster satellites in the same longitudinal sector as DEMETER but at ~5 RE. The analysis of the Spatio Temporal Analysis of Field Fluctuations data on board C1 reveals that the magnetic field spectrogram has peaks close to harmonics of the local proton gyrofrequency as usually reported. It is shown that the DEMETER and Cluster EN waves have a similar QP modulation but with slightly different period and frequency.
“Explosively growing” vortices of unstably stratified atmosphere
Authors: Onishchenko O. G. , Horton W. , Pokhotelov O. A. , Fedun V. 
Published: September 2016

AbstractA new type of “explosively growing” vortex structure is investigated theoretically in the framework of ideal fluid hydrodynamics. It is shown that vortex structures may arise in convectively unstable atmospheric layers containing background vorticity. From an exact analytical vortex solution the vertical vorticity structure and toroidal speed are derived and analyzed. The assumption that vorticity is constant with height leads to a solution that grows explosively when the flow is inviscid. The results shown are in agreement with observations and laboratory experiments