bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the marketing potential of location-based mobile games
Authors: Wu Linwan , Stilwell Matthew A. 
Published: December 2017

Purpose
Location-based mobile games, like Pokémon GO, have been tremendously prevalent in recent years. Marketing professionals have considered this type of game as a promising marketing platform. The purpose of this study is to explore the marketing potential of location-based mobile games by examining players’ responses to sponsors featured in Pokémon GO.

Design/methodology/approach
A survey was conducted among gamers of Pokémon GO to examine the psychological process of the gameplay, and how it influences some marketing outcomes. A conceptual model was built based on the survey results.

Findings
Results indicated that gamers of Pokémon GO experienced spatial presence, which positively influenced their attitudes toward and intentions to visit the sponsors. Moreover, spatial presence was positively influenced by players’ game engagement, perceived mobility and contextual perceived value. Some motives of playing Pokémon GO were also identified, including the entertainment motive and social motive.

Originality/value
This study is the first one to analyze the marketing potential of Pokémon GO, which is a successful location-based mobile game. The results are meaningful to marketing professionals who are interested in this innovative media platform. This study is also the first one to apply the theory of spatial presence to the investigations of this type of game. It showcases the power of this theory in guiding the research of interactive marketing with mobile gaming.
Leveraging medium-sized sport events to attract club participants
Authors: Hoskyn Katharine , Dickson Geoff , Sotiriadou Popi 
Published: December 2017

Purpose
Sport participation is the lifeblood of community sport clubs. The purpose of this paper is to investigate how sport clubs can leverage participation from local, medium-sized, elite sport events.

Design/methodology/approach
This study used an action research approach where researchers, along with representative stakeholders from two elite tennis tournaments and 23 local tennis organizations, collaborated to develop and implement a series of interventions as part of a wider leveraging plan. The interventions were developed and evaluated in one cycle of action research that incorporated predominantly qualitative research methods.

Findings
The interventions stimulated the interest of event spectators by offering a free tennis lesson at a participating club. However, the conversion from interest to club participation was limited.

Practical implications
Key recommendations for clubs to leverage participation from a medium-sized event include: a leveraging plan should consider the resources and capacity of local community sport clubs; clubs should act collectively and collaboratively; and clubs should have a strong physical presence at the event(s).

Originality/value
Regional sports organizations can utilize existing collaborative networks to enable community clubs to design and implement event-leveraging initiatives. This study also highlights the limited capacity of community sport clubs to leverage participation outcomes from medium-sized annual events. The use of collaborative networks may ameliorate the organizational capacity deficiencies of clubs.
Comparison of three kinds of sensors used to identify the incipient cavitation
Authors: Kang Yang Zi , Feng Chi , Liu Liang Zhi , Gao Shan , Cang Yan 
Published: December 2017

Purpose
Hydroelectric power is widely used because it is environmental friendly, renewable and green. The cavitation is an inevitable phenomenon during the operation of hydro turbine, which is related to the efficiency and service life of the unit. This paper aims to discriminate the phenomenon of the incipient cavitation, prevent the early destruction and avoid the irreversible damage to hydro turbine.

Design/methodology/approach
The paper tries to find out the characteristics of cavitation entirely through a variety of features. The method comprises collection of the signals using a hydrophone, acceleration sensor and acoustic emission sensor; analyzing cavitation signal by using the way of wavelet time-frequency, peak factor and power spectral density; and comparing the different wavelet basis for analyzing signals and find the most suitable one.

Findings
The analyzed results show that the wavelet basis of morlet is more suitable for the cavitation signals. The hydrophone can distinguish the different operating conditions and discriminate the difference between the phenomenon of incipient cavitation and the other state of cavitation. The results show that when the hydrophone and acceleration sensors are used, the accuracy rate goes up to 75 per cent, which meets the requirements for the detection for incipient cavitation.

Originality/value
This paper focuses on finding the best sensor to discriminate the operating state of incipient cavitation to prevent early destruction.
Long-period fiber grating cascaded to thin-core fiber for simultaneous measurement of liquid refractive-index and temperature
Authors: Jiang Meng , Wang Ze-Ming , Zhao Zhong-Ze , Li Kun , Yang Fu 
Published: December 2017

Purpose
The purpose of this paper is to demonstrate a simple fiber sensor for simultaneous measurement of liquid refractive-index (RI) and temperature.

Design/methodology/approach
The sensor structure is formed by a long period fiber grating cascaded with a section of thin-core fiber. The long period fiber grating is fabricated on single mode fiber, followed by a section of 20-mm length thin-core fiber which is a modal interferometer.

Findings
Cladding mode interference between long period fiber grating and thin-core fiber modal interferometer is weak in the experimental investigation. Both of these two cladding mode type fiber devices are sensitive to surrounding RI and temperature. So the RI and temperature can be measured simultaneously by monitoring the spectral characteristics of the compound sensor. The sensitivity is calibrated and sensor matrix is provided in the experiment.

Originality/value
This proposed fiber sensor is simple, tough, cost-effective and suitable for discriminate the liquid RI and temperature with high sensitivity.
House of Bounce
Authors: Cox Tod , Subramanian Ram 
Published: December 2017

Synopsis
Tom Feldman took a buyout from a large technology company and used part of the money to enroll in the MBA program of a reputed university in the metropolitan Houston, Texas area. While in the MBA program, Tom began evaluating potential businesses with the objective of identifying one that would suit his needs. As part of an MBA course in marketing, Tom put together a student team to conduct marketing research on an opportunity to open a party center in Houston. After his team completed the study, Tom had both financial and marketing data to make a decision about the launch.

Research methodology
Teaching case based on the primary research.

Relevant courses and levels
This case is suited for a marketing course at both the undergraduate and graduate levels.
Social behaviour and gut microbiota in red‐bellied lemurs (Eulemur rubriventer): In search of the role of immunity in the evolution of sociality
Authors: Raulo Aura , Ruokolainen Lasse , Lane Avery , Amato Katherine , Knight Rob , Leigh Steven , Stumpf Rebecca , White Bryan , Nelson Karen E. , Baden Andrea L. , Tecot Stacey R. 
Published: December 2017

Abstract

Vertebrate gut microbiota form a key component of immunity and a dynamic link between an individual and the ecosystem. Microbiota might play a role in social systems as well, because microbes are transmitted during social contact and can affect host behaviour.

Combining methods from behavioural and molecular research, we describe the relationship between social dynamics and gut microbiota of a group‐living cooperative species of primate, the red‐bellied lemur (Eulemur rubriventer). Specifically, we ask whether patterns of social contact (group membership, group size, position in social network, individual sociality) are associated with patterns of gut microbial composition (diversity and similarity) between individuals and across time.

Red‐bellied lemurs were found to have gut microbiota with slight temporal fluctuations and strong social group‐specific composition. Contrary to expectations, individual sociality was negatively associated with gut microbial diversity. However, position within the social network predicted gut microbial composition.

These results emphasize the role of the social environment in determining the microbiota of adult animals. Since social transmission of gut microbiota has the potential to enhance immunity, microbiota might have played an escalating role in the evolution of sociality.
Experimentally simulating warmer and wetter climate additively improves rangeland quality on the Tibetan Plateau
Authors: Xu Wei , Zhu Mengyao , Zhang Zhenhua , Ma Zhiyuan , Liu Huiying , Chen Litong , Cao Guangmin , Zhao Xinquan , Schmid Bernhard , He Jin‐Sheng 
Published: December 2017

Abstract

The vast expanses of rangeland on the Tibetan Plateau, which support the livelihood of c. 9.8 million local inhabitants, have experienced rapid climate warming over the past 50 years. At the same time, precipitation has increased in large parts of the Plateau but decreased in other parts, particularly in the northwest. These trends are predicted to continue into the future. However, their potential effects on rangeland quality remain unclear.

We conducted a two‐factor field experiment in which we manipulated temperature (control or warming by 1.5–1.8°C) and precipitation (control or 50% reduction or increase in rainfall) in an alpine grassland on the northeastern Tibetan Plateau, starting in 2011. From 2014 to 2016, we measured forage production and community composition, and in 2015 forage quality (crude protein, cell‐soluble contents, hemicellulose, cellulose, lignin and digestibility) was represented by seven abundant species.

Overall, warming did not change total forage production at plant community level, but increased legume production and decreased non‐legume forb production. Increased and reduced precipitation enhanced and decreased forage production by 18.2% and 12.9% respectively. Increased precipitation in particular increased grass and sedge production, but not legume production.

Forage quality showed species‐specific responses to the simulated climate changes. At community level, warming and reduced precipitation improved forage quality, which were mainly caused by a shift in community composition towards more legumes, rather than the direct effects of simulated climate changes. Meanwhile, increased precipitation did not reduce forage quality, despite the precipitation‐induced increase in forage production.

Integrating forage production and quality into nutrient production as a measure of rangeland quality, we found that warming and increased precipitation additively improved rangeland quality, while reduced precipitation decreased it.

Synthesis and applications. Rangeland quality, an important ecosystem provisioning service, will benefit from a warmer climate on the Tibetan Plateau in the regions with a predicted increase in precipitation, but not in those regions where precipitation might be reduced in the future. We suggest management strategies, including reseeding native legumes, establishing sustainable pastures and assisting the exchange of harvested forage, to cope with the challenges posed by these different climate change scenarios.
Local biodiversity erosion in south Brazilian grasslands under moderate levels of landscape habitat loss
Authors: Staude Ingmar R. , Vélez‐Martin Eduardo , Andrade Bianca O. , Podgaiski Luciana Regina , Boldrini Ilsi I. , Mendonça Milton , Pillar Valério D. , Overbeck Gerhard E. 
Published: December 2017

Abstract

Habitat loss is one of the greatest threats to biodiversity, exerting negative effects on the ecological viability of natural vegetation remnants. The south Brazilian grasslands belong to one of the largest temperate grassland regions in the world, but have lost 50% of their natural extent in the past 35 years. To date, there is no empirical evidence for the effects of habitat loss on these grasslands' biological diversity, undermining their conservation.

Using data from a large‐scale biodiversity survey, we asked if local plant communities respond to levels of habitat loss representative of the entire region (≤50%). Vegetation in grassland remnants was sampled in 24 landscapes at three localities each, using nine plots per locality. To investigate whether species losses were a consequence of stochastic or nonrandom local extinctions and whether plant communities became more homogenized, we evaluated species richness, beta‐diversity components (spatial turnover and nestedness), and phylogenetic diversity, in respect to landscape change. In part of the landscapes, arthropods were sampled to investigate if loss of plant diversity had a cascading effect on other trophic levels. We evaluated generic richness of ants, an omnivore group with high levels of plant associations, in respect to a plant community's phylogenetic diversity.

Local plant communities in landscapes with less grassland cover had fewer species, less spatial turnover, increased nestedness and lower phylogenetic diversity. Our results suggest that the observed species loss can be linked to taxonomic homogenization and is nonrandom, decreasing evolutionary diversity within the community. Furthermore, ant richness declined by 50% in plant communities with the lowest phylogenetic diversity, suggesting that effects of habitat loss propagate to higher trophic levels.

Policy implications. We conclude that the biological diversity of south Brazilian grasslands, at the producer and consumer level, is at risk under the current rate of land‐use conversion, even at habitat losses below 50%. To avoid substantial biodiversity loss, conservation and more restrictive policies for conversion of native grasslands to different land uses in South Brazil are urgently needed.
Clinical relevance of deferasirox trough levels in β‐thalassemia patients
Authors: Allegra Sarah , Massano Davide , De Francia Silvia , Longo Filomena , Piccione Francesca , Pirro Elisa , Cusato Jessica , D'Avolio Antonio , Piga Antonio 
Published: December 2017

SummaryWe evaluated the role of deferasirox therapeutic drug monitoring in order to avoid toxicity or treatment failure. Plasma concentrations, measured between two consecutive liver iron determinations, were determined at the end of dosing interval. Fifty‐four β‐thalassemic adult patients were enrolled: 50% were males; median age was 32.3 years (IQR 19.1‐41.7 years) and median body mass index was 22.25 kg/m2 (IQR 20.24‐23.75 kg/m2). The mean deferasirox dose was 28.6 ± 6.3 mg/kg/d and mean plasma concentration was 17.3 ± 16.8 μg/mL. Drug levels showed lower results in males. Deferasirox concentration was significantly correlated with serum creatinine levels (P = .01) and serum ferritin (P < .0001). The assessment of deferasirox therapeutic drug monitoring could help clinicians to predict patient responses and to optimize the therapy.
Anti‐inflammatory and anticancer activities of water‐soluble peptide extracts of buffalo and cow milk Cheddar cheeses
Authors: Rafiq Saima , Huma Nuzhat , Rakariyatham Kanyasiri , Hussain Imtiaz , Gulzar Nabila , Hayat Imran 
Published: December 2017

This article aimed to assess the anti‐inflammatory and anticancer potential of water‐soluble peptide (WSP) extracts from buffalo and cow milk Cheddar cheeses. Anti‐inflammatory activity was evaluated on the basis of nitric oxide (NO) production in lipopolysaccharide‐stimulated macrophage (RAW‐264.7) cells. A cell viability assay, cell cycle arrest and apoptosis were performed to explore anticancer activity in a colon cancer model (HT‐29). The WSP extracts of both Cheddar cheeses effectively inhibited NO production in activated macrophages. Maximum growth inhibition was observed in the HT‐29 cells at concentrations of 400 and 500 μg/mL. A significant increase in cell population at G0/G1 phase of the cell cycle was observed. Moreover, the WSP extracts also induced extensive apoptosis in colon cancer cells.
Evidence‐Based Medicine and State Health Care Coverage: The Washington Health Technology Assessment Program
Authors: Rothman David J. , Blackwood Kristy L. , Adair Whitney , Rothman Sheila M. 
Published: December 2017

ObjectiveTo evaluate the Washington State Health Technology Assessment Program (WHTAP).Study SettingWashington State Health Technology Assessment Program proceedings in Seattle, Washington.Data Collection and Study DesignWe assessed the program through observation of its proceedings over a 5‐year period, 2009–2014. We conducted detailed analyses of the documents it produced and reviewed relevant literature.Principal FindingsWashington State Health Technology Assessment Program is unique compared to other state and federal programs. It has successfully applied evidence‐based medicine to health care decision making, limited by the strength of available data. It claims cost savings, but they are not substantiated.ConclusionsWashington State Health Technology Assessment Program is a useful model for other states considering implementation of technology assessment programs. We provide key lessons for improving WHTAP's process.
Classification Improvements in Automated Gunshot Residue (GSR) Scans
Authors: Mandel Micha , Israelsohn Azulay Osnat , Zidon Yigal , Tsach Tsadok , Cohen Yaron 
Published: December 2017

AbstractClassification of particles as gunshot residues (GSRs) is conducted using a semiautomatic approach in which the system first classifies particles based on an automatic elemental analysis, and then, examiners manually analyze particles having compositions which are characteristic of or consistent with GSRs. Analyzing all the particles in the second stage is time consuming with many particles classified by the initial automated system as being potentially GSRs excluded as such by the forensic examiner. In this paper, a new algorithm is developed to improve the initial classification step. The algorithm is based on a binary tree that was trained on almost 16,000 particles from 43 stubs used to sample hands of suspects. The classification algorithm was tested on 5,900 particles from 23 independent stubs and performed very well in terms of false positive and false negative rates. A routine use of the new algorithm can reduce significantly the analysis time of GSRs.
Targeted in situ metatranscriptomics for selected taxa from mesophilic and thermophilic biogas plants
Authors: Stolze Yvonne , Bremges Andreas , Maus Irena , Pühler Alfred , Sczyrba Alexander , Schlüter Andreas 
Published: December 2017

SummaryBiogas production is performed anaerobically by complex microbial communities with key species driving the process. Hence, analyses of their in situ activities are crucial to understand the process. In a previous study, metagenome sequencing and subsequent genome binning for different production‐scale biogas plants (BGPs) resulted in four genome bins of special interest, assigned to the phyla Thermotogae, Fusobacteria, Spirochaetes and Cloacimonetes, respectively, that were genetically analysed. In this study, metatranscriptome sequencing of the same BGP samples was conducted, enabling in situ transcriptional activity determination of these genome bins. For this, mapping of metatranscriptome reads on genome bin sequences was performed providing transcripts per million (TPM) values for each gene. This approach revealed an active sugar‐based metabolism of the Thermotogae and Spirochaetes bins and an active amino acid‐based metabolism of the Fusobacteria and Cloacimonetes bins. The data also hint at syntrophic associations of the four corresponding species with methanogenic Archaea.
Politeness, Hypocrisy and Protestant Dissent in England after the Toleration Act, c.1689‐c.1750
Authors: Brown Carys 
Published: December 2017

AbstractThe concept of politeness has been central to studies of eighteenth‐century England; less attention has been given to its impact on religious coexistence. This article argues that, while politeness has typically been associated with rejection of the religious divisions of the previous century, it could also be used to perpetuate them. Focusing on the position of Protestant Dissenters in relation to wider society after the Toleration Act of 1689, it argues that cultures of politeness complicated, rather than eased, their social integration. Furthermore, it highlights the centrality of religious questions to social and cultural change in eighteenth‐century England.
Measuring the gut microbiome in birds: Comparison of faecal and cloacal sampling
Authors: Videvall Elin , Strandh Maria , Engelbrecht Anel , Cloete Schalk , Cornwallis Charlie K. 
Published: December 2017

AbstractThe gut microbiomes of birds and other animals are increasingly being studied in ecological and evolutionary contexts. Numerous studies on birds and reptiles have made inferences about gut microbiota using cloacal sampling; however, it is not known whether the bacterial community of the cloaca provides an accurate representation of the gut microbiome. We examined the accuracy with which cloacal swabs and faecal samples measure the microbiota in three different parts of the gastrointestinal tract (ileum, caecum, and colon) using a case study on juvenile ostriches, Struthio camelus, and high‐throughput 16S rRNA sequencing. We found that faeces were significantly better than cloacal swabs in representing the bacterial community of the colon. Cloacal samples had a higher abundance of Gammaproteobacteria and fewer Clostridia relative to the gut and faecal samples. However, both faecal and cloacal samples were poor representatives of the microbial communities in the caecum and ileum. Furthermore, the accuracy of each sampling method in measuring the abundance of different bacterial taxa was highly variable: Bacteroidetes was the most highly correlated phylum between all three gut sections and both methods, whereas Actinobacteria, for example, was only strongly correlated between faecal and colon samples. Based on our results, we recommend sampling faeces, whenever possible, as this sample type provides the most accurate assessment of the colon microbiome. The fact that neither sampling technique accurately portrayed the bacterial community of the ileum nor the caecum illustrates the difficulty in noninvasively monitoring gut bacteria located further up in the gastrointestinal tract. These results have important implications for the interpretation of avian gut microbiome studies.
Role of intravenous immunoglobulin in the treatment of Kawasaki disease
Authors: Lo Mindy S. , Newburger Jane W. 
Published: December 2017

AbstractIntravenous immunoglobulin (IVIg) is a purified plasma product that is used for many immune‐deficient conditions and autoimmune conditions. Use of IVIg for treatment for Kawasaki disease (KD) is critical for control of inflammation. The American Heart Association (AHA) recommends a single infusion of 2 g/kg preferably given during the first 10 days of illness. In this review, we have discussed the possible mechanisms of action of IVIg in KD and its clinical usage in this condition.