bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trauma Early Mortality Prediction Tool (TEMPT) for assessing 28-day mortality
Authors: Kunitake Ryan C , Kornblith Lucy Z , Cohen Mitchell Jay , Callcut Rachael A 
Published: January 2018

BackgroundPrior mortality prediction models have incorporated severity of anatomic injury quantified by Abbreviated Injury Severity Score (AIS). Using a prospective cohort, a new score independent of AIS was developed using clinical and laboratory markers present on emergency department presentation to predict 28-day mortality.MethodsAll patients (n=1427) enrolled in an ongoing prospective cohort study were included. Demographic, laboratory, and clinical data were recorded on admission. True random number generator technique divided the cohort into derivation (n=707) and validation groups (n=720). Using Youden indices, threshold values were selected for each potential predictor in the derivation cohort. Logistic regression was used to identify independent predictors. Significant variables were equally weighted to create a new mortality prediction score, the Trauma Early Mortality Prediction Tool (TEMPT) score. Area under the curve (AUC) was tested in the validation group. Pairwise comparison of Trauma Injury Severity Score (TRISS), Revised Trauma Score, Glasgow Coma Scale, and Injury Severity Score were tested against the TEMPT score.ResultsThere was no difference between baseline characteristics between derivation and validation groups. In multiple logistic regression, a model with presence of traumatic brain injury, increased age, elevated systolic blood pressure, decreased base excess, prolonged partial thromboplastin time, increased international normalized ratio (INR), and decreased temperature accurately predicted mortality at 28 days (AUC 0.93, 95% CI 0.90 to 0.96, P<0.001). In the validation cohort, this score, termed TEMPT, predicted 28-day mortality with an AUC 0.94 (95% CI 0.92 to 0.97). The TEMPT score preformed similarly to the revised TRISS score for severely injured patients and was highly predictive in those having mild to moderate injury.DiscussionTEMPT is a simple AIS-independent mortality prediction tool applicable very early following injury. TEMPT provides an AIS-independent score that could be used for early identification of those at risk of doing poorly following even minor injury.Level of evidenceLevel II.
Discovering Communities and Anomalies in Attributed Graphs
Authors: Perozzi Bryan , Akoglu Leman 
Published: January 2018

Given a network with node attributes, how can we identify communities and spot anomalies? How can we characterize, describe, or summarize the network in a succinct way? Community extraction requires a measure of quality for connected subgraphs (e.g., social circles). Existing subgraph measures, however, either consider only the connectedness of nodes inside the community and ignore the cross-edges at the boundary (e.g., density) or only quantify the structure of the community and ignore the node attributes (e.g., conductance). In this work, we focus on node-attributed networks and introduce: (1) a
new measure of subgraph quality
for attributed communities called normality, (2) a
community extraction
algorithm that uses normality to extract communities and a few characterizing attributes per community, and (3) a
summarization and interactive visualization
approach for attributed graph exploration. More specifically, (1) we first introduce a new measure to quantify the normality of an attributed subgraph. Our normality measure carefully utilizes structure and attributes together to quantify both the internal consistency and external separability. We then formulate an objective function to automatically infer a few attributes (called the “focus”) and respective attribute weights, so as to maximize the normality score of a given subgraph. Most notably, unlike many other approaches, our measure allows for many cross-edges as long as they can be “exonerated;” i.e., either (i) are expected under a null graph model, and/or (ii) their boundary nodes do not exhibit the focus attributes. Next, (2) we propose AMEN (for Attributed Mining of Entity Networks), an algorithm that simultaneously discovers the communities and their respective focus in a given graph, with a goal to maximize the total normality. Communities for which a focus that yields high normality cannot be found are considered low quality or anomalous. Last, (3) we formulate a summarization task with a multi-criteria objective, which selects a subset of the communities that (i) cover the entire graph well, are (ii) high quality and (iii) diverse in their focus attributes. We further design an interactive visualization interface that presents the communities to a user in an interpretable, user-friendly fashion. The user can explore all the communities, analyze various algorithm-generated summaries, as well as devise their own summaries interactively to characterize the network in a succinct way. As the experiments on real-world attributed graphs show, our proposed approaches effectively find anomalous communities and outperform several existing measures and methods, such as conductance, density, OddBall, and SODA. We also conduct extensive user studies to measure the capability and efficiency that our approach provides to the users toward network summarization, exploration, and sensemaking.
High-definition transcranial direct-current stimulation of the right M1 further facilitates left M1 excitability during crossed facilitation
Authors: Cabibel Vincent , Muthalib Makii , Teo Wei-Peng , Perrey Stephane 
Published: January 2018

The crossed-facilitation (CF) effect refers to when motor-evoked potentials (MEPs) evoked in the relaxed muscles of one arm are facilitated by contraction of the opposite arm. The aim of this study was to determine whether high-definition transcranial direct-current stimulation (HD-tDCS) applied to the right primary motor cortex (M1) controlling the left contracting arm [50% maximum voluntary isometric contraction (MVIC)] would further facilitate CF toward the relaxed right arm. Seventeen healthy right-handed subjects participated in an anodal and cathodal or sham HD-tDCS session of the right M1 (2 mA for 20 min) separated by at least 48 h. Single-pulse transcranial magnetic stimulation (TMS) was used to elicit MEPs and cortical silent periods (CSPs) from the left M1 at baseline and 10 min into and after right M1 HD-tDCS. At baseline, compared with resting, CF (i.e., right arm resting, left arm 50% MVIC) increased left M1 MEP amplitudes (+97%) and decreased CSPs (−11%). The main novel finding was that right M1 HD-tDCS further increased left M1 excitability (+28.3%) and inhibition (+21%) from baseline levels during CF of the left M1, with no difference between anodal and cathodal HD-tDCS sessions. No modulation of CSP or MEP was observed during sham HD-tDCS sessions. Our findings suggest that CF of the left M1 combined with right M1 anodal or cathodal HD-tDCS further facilitated interhemispheric interactions during CF from the right M1 (contracting left arm) toward the left M1 (relaxed right arm), with effects on both excitatory and inhibitory processing. NEW & NOTEWORTHY This study shows modulation of the nonstimulated left M1 by right M1 HD-tDCS combined with crossed facilitation, which was probably achieved through modulation of interhemispheric interactions.
Culture-specific and individual affective factors in professional communication
Authors: Anderson Robin , Lehman Iga Maria 
Published: January 2018

Abstract
In this paper we set out to consider the place of the English language in globalised communities. The hegemony, which English enjoys, has ramifications for how it is taught, how and why it is learned and how it is used. We argue that there is a need to consider more socio-cultural and individual factors in the learning and use of English as a lingua franca as these factors constitute crucial aids to successful cross-cultural interactions in professional environments. The latest research on lingua franca English (LFE) (Firth & Wagner, 1997; Kramsch, 2002; Larsen-Freeman, 2002; Block, 2003; House, 2003; Canagarajah, 2006a; Lantolf & Thorne, 2006; Atkinson, Churchill, Nishino & Okada, 2007) confirms our position since it reveals what has always been the experience of multilingual speakers, i.e., “Language learning and use succeed through performance strategies, situational resources, and social negotiations in fluid communicative contexts. Proficiency is therefore practice-based, adaptive, and emergent” (Canagarajah, 2007: 923).
Distinctions in procedural meaning
Authors: Bardzokas Valandis 
Published: January 2018

Abstract
The current paper aims to investigate the distinctions in meaning between two prototypical markers of contrast in Modern Greek, i.e. alla and ma, from a relevance-theoretic viewpoint. At first sight, the two markers seem freely interchangeable across contexts, creating the impression that they basically share the same meaning. However, a more careful exploration of the contextual occurrences of these markers unravels their finely grained distinctions in meaning. This type of exploration requires a detailed categorization of the types of context that license or preclude the application of the markers at hand. In this sense, specific contexts highlight aspects of interpretation that motivate the use of one of the markers but not the other. Specifically, as it turns out, while the use of alla is chiefly associated with contexts of procedural elimination, in standard relevance-theoretic terms, the use of ma is justified in relation to expressing the speaker’s attitude of surprise to a contextual assumption constructed by the hearer, in addition to effecting procedural elimination. In this sense, ma proves to encode a dual constraint on the implicitly communicated content of an utterance, explained univocally in procedural terms.
Online News Media, Religious Identity and Their Influence on Gendered Politics: Observations from Malawi’s 2014 Elections
Authors: Gunde Anthony M. 
Published: January 2018

The rise of the internet has offered the opportunity for the news media to communicate with audiences in many significant ways that may have profound consequences in the shaping of public opinion and transforming lives in the global sphere. Through a Critical Discourse Analysis (CDA), this article examines ways in which online news media could be used to reinforce gender stereotypes by promoting patriarchal religious beliefs and how this may have huge implications on women’s empowerment with regard to political leadership roles in developing democracies.
The analysis is drawn from the 2014 Malawi elections, in which a major opposition party used a campaign slogan peppered with sexist religious and cultural connotations to ridicule and vote out of office southern Africa’s first ever female President – Joyce Banda and her People Party (PP). In May 2014, Malawi held national elections and the main contestants were former President Banda representing the PP, Peter Mutharika of the Democratic Progressive Party (DPP), Lazarus Chakwera of the Malawi Congress Party (MCP) and Atupele Muluzi of the United Democratic Front (UDF). Mutharika and the DPP won the elections to wrestle away the presidency from Banda and her People’s Party. This article discusses the campaign slogan – Sesa Joyce Sesa – created by the DPP to attack former President Banda in which Malawi’s significant online news media sites played a critical role in the diffusion of the gendered campaign mantra to resonate with the religious identity of majority the electorate. The article reflects on the potential of new media to consolidate deep-rooted religious and cultural beliefs that marginalise women for leadership positions and the effect this may have on bridging gender inequalities, particularly in political representation in developing democracies.
Lexical Elements of Slavic Origin in Judezmo on South Slavic Territory, 16–19th Centuries: Uriel Weinreich and the History of Contact Linguistics
Authors: Bunis David M. 
Published: January 2018

AbstractFrom the 19th–20th-century beginnings of modern linguistics, scholars reported on various results of interactions between diverse language speakers; but it was only with Uriel Weinreich’sLanguages in Contact(1953) that a solid theoretical basis for the systematic study of contact linguistics was elaborated. The present article studies lexical influences from South Slavic on Judezmo (Ladino/Judeo-Spanish) resulting from contact during the 16th–19th centuries between speakers of these two languages in the regions that, between 1918 and 1992, were known jointly as Yugoslavia. During the Ottoman and then Austro-Hungarian periods, borrowings in local Judezmo from South Slavic were relatively few compared with Turkisms. But from the nineteenth century, when the South Slavs gained political independence, Serbo-Croatian exerted an ever-increasing influence on Judezmo in this region. The case of Judezmo there differs considerably from Yiddish in Slavic Eastern Europe throughout the same period, as described by Uriel Weinreich and others.
The Shallow Overturning Circulation in the Indian Ocean
Authors: Nagura Motoki , McPhaden Michael J. 
Published: January 2018

AbstractThe number of in situ observations in the Indian Ocean has dramatically increased over the past 15 years thanks to the implementation of the Argo profiling float program. This study estimates the mean circulation in the Indian Ocean using hydrographic observations obtained from both Argo and conductivity–temperature–depth (CTD) observations. Absolute velocity at the Argo float parking depth is used so there is no need to assume a level of no motion. Results reveal previously unknown features in addition to well-known currents and water masses. Some newly identified features include the lack of an interior pathway to the equator from the southern Indian Ocean in the pycnocline, indicating that water parcels must transit through the western boundary to reach the equator. High potential vorticity (PV) intrudes from the western coast of Australia in the depth range of the Subantarctic Mode Water, which leads to a structure similar to a PV barrier. The subtropical anticyclonic gyre retreats poleward with depth, as happens in the subtropical Atlantic and Pacific. An eastward flow was found in the eastern basin along 15°S at the depth of the Antarctic Intermediate Water—a feature expected from property distributions but never before detected in velocity estimates. Meridional mass transport indicates about 10 Sv (1 Sv ≡ 106 m3 s−1) southward flow at 6°S and 18 Sv northward flow at 20°S, which results in meridional convergence of currents and thermocline depression at about 16°–20°S. These estimated absolute velocities agree well with those of an ocean reanalysis, which lends credibility to the strictly databased analysis.
A Barotropic Model of Eddy Saturation
Authors: Constantinou Navid C. 
Published: January 2018

AbstractEddy saturation refers to a regime in which the total volume transport of an oceanic current is insensitive to the wind stress strength. Baroclinicity is currently believed to be the key to the development of an eddy-saturated state. In this paper, it is shown that eddy saturation can also occur in a purely barotropic flow over topography, without baroclinicity. Thus, eddy saturation is a fundamental property of barotropic dynamics above topography. It is demonstrated that the main factor controlling the appearance or not of eddy-saturated states in the barotropic setting is the structure of geostrophic contours, that is, the contours of f/H (the ratio of the Coriolis parameter to the ocean’s depth). Eddy-saturated states occur when the geostrophic contours are open, that is, when the geostrophic contours span the whole zonal extent of the domain. This minimal requirement for eddy-saturated states is demonstrated using numerical integrations of a single-layer quasigeostrophic flow over two different topographies characterized by either open or closed geostrophic contours with parameter values loosely inspired by the Southern Ocean. In this setting, transient eddies are produced through a barotropic–topographic instability that occurs because of the interaction of the large-scale zonal flow with the topography. By studying this barotropic–topographic instability insight is gained on how eddy-saturated states are established.
Celecoxib
Authors: Cada Dennis J. , Baker Danial E. 
Published: January 2018

Each month, subscribers to The Formulary® Monograph Service receive five to six researched monographs on drugs that are newly released or are in late Phase III trials. The monographs are targeted to your Pharmacy and Therapeutics Committee. Subscribers also receive monthly one-page summary monographs on the agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation (DUE) is also provided each month. The monographs are published in printed form and on diskettes that allow customization. Subscribers to the The Formulary Monograph Service also receive access to a pharmacy bulletin board called The Formulary Information Exchange (The F.I.X). All topics pertinent to clinical pharmacy are discussed on The F.I.X. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. If you would like information about The Formulary Monograph Service or The F.I.X., call The Formulary at 800-322-4349. The May 1999 Formulary monographs are on pantoprazole, denileukin diftitox, nesiritide, sirolimus, and sodium ferric gluconate complex in sucrose. The DUE is on sodium ferric gluconate complex in sucrose.
Lyme Disease Vaccine
Authors: Cada Dennis J. , Levien Terri , Baker Danial E. 
Published: January 2018

Each month, subscribers to The Formulary® Monograph Service receive five to six researched monographs on drugs that are newly released or are in late Phase III trials. The monographs are targeted to your Pharmacy and Therapeutics Committee. Subscribers also receive monthly one-page summary monographs on the agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation (DUE) is also provided each month. The monographs are published in printed form and on diskettes that allow customization. Subscribers to the The Formulary Monograph Service also receive access to a pharmacy bulletin board called The Formulary Information Exchange (The F.I.X). All topics pertinent to clinical pharmacy are discussed on The F.I.X. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. If you would like information about The Formulary Monograph Service or The F.I.X., call The Formulary at 800-322-4349. The June 1999 Formulary monographs are on levalbuterol inhalation solution, itraconazole injection, amprenavir, pioglitazone, and cytarabine liposome injection. The DUE is on itraconazole injection.
Measuring Pediatric Iron Products Safely; Tricky Fingers the Check Please!; Considering Error Potential When Adding Drugs to Your Formulary
Authors: Cohen Michael R. 
Published: January 2018

These medication errors have occurred in health care facilities at least once. They will happen again—perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them in your inservice training programs. Your assistance is required to continue this feature. The reports described here were received through the USP Medication Errors Reporting Program, which is presented in cooperation with the Institute of Safe Medication Practices. If you have encountered medication errors and would like to report them, you may call USP toll-free, 24 hours a day, at 1-800-233-7767 (1-800-23-ERROR). Any reports published by ISMP will be anonymous. Comments are also invited; the writer's names will be published if desired. ISMP may be contacted at the address shown below.
Felt-Tipped Pens; 1999 Recipients of the Pinnacle Award; Outmoded Apothecary System Still Causing Medication Errors; Medication Error Prevention “Toolbox”
Authors: Cohen Michael R. 
Published: January 2018

These medication errors have occurred in health care facilities at least once. They will happen again—perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them in your inservice training programs. Your assistance is required to continue this feature. The reports described here were received through the USP Medication Errors Reporting Program, which is presented in cooperation with the Institute of Safe Medication Practices. If you have encountered medication errors and would like to report them, you may call USP toll-free, 24 hours a day, at 1-800-233-7767 (1-800-23-ERROR). Any reports published by ISMP will be anonymous. Comments are also invited; the writer's names will be published if desired. ISMP may be contacted at the address shown below.
Hespan and Heparin Mix-Ups near Fatal Pediatric Accident Related to Common Cost-Cutting Measure Negative List of Medical Abbreviations: The Best Policy
Authors: Cohen Michael R. 
Published: January 2018

These medication errors have occurred in health care facilities at least once. They will happen again—perhaps where you work. Through education and alertness of personnel and procedural safeguards, they can be avoided. You should consider publishing accounts of errors in your newsletters and/or presenting them in your inservice training programs. Your assistance is required to continue this feature. The reports described here were received through the USP Medication Errors Reporting Program, which is presented in cooperation with the Institute of Safe Medication Practices. If you have encountered medication errors and would like to report them, you may call USP toll-free, 24 hours a day, at 1-800-233-7767 (1-800-23-ERROR). Any reports published by ISMP will be anonymous. Comments are also invited; the writer's names will be published if desired. ISMP may be contacted at the address shown below.
Rosiglitazone
Authors: Cada Dennis J. , Baker Danial E. , Levien Terri 
Published: January 2018

Each month, subscribers to The Formulary® Monograph Service receive five to six researched monographs on drugs that are newly released or are in late Phase III trials. The monographs are targeted to your Pharmacy and Therapeutics Committee. Subscribers also receive monthly one-page summary monographs on the agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation (DUE) is also provided each month. The monographs are published in printed form and on diskettes that allow customization. Subscribers to the The Formulary Monograph Service also receive access to a pharmacy bulletin board called The Formulary Information Exchange (The F.I.X). All topics pertinent to clinical pharmacy are discussed on The F.I.X. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. If you would like information about The Formulary Monograph Service or The F.I.X., call The Formulary at 800-322-4349. The November 1999 Formulary monographs are on rapacuronium, rabeprazole, zaleplon, alosetron, and ganirelix acetate. The DUE is on zaleplon.