bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phenotype and Treatment of Breast Cancer in HIV-Positive and -Negative Women in Cape Town, South Africa
Authors: Langenhoven Lizanne , Barnardt Pieter , Neugut Alfred I. , Jacobson Judith S. 
Published: March 2016

Purpose An estimated 5.9 million people in South Africa are infected with HIV. Because antiretroviral therapy has made infection with HIV a treatable, chronic condition, HIV-infected individuals are now surviving to middle and older age. We investigated the implications of HIV status for breast cancer in South Africa. Methods We compared clinical and demographic characteristics of women newly diagnosed with a first primary breast cancer at Tygerberg Hospital, Cape Town, South Africa, from January 2010 to December 2011 by HIV status. We then compared HIV-positive patients with HIV-negative controls, matched 2:1 on age and ethnicity, with respect to chemotherapy regimens, toxicities, completion of systemic chemotherapy, and changes in CD4 cell count. Results Of 586 women with breast cancer, 31 (5.3%) were HIV positive, 420 (71.7%) were HIV negative, and 135 (23%) were untested for HIV. Women with HIV were younger than other women (P < .001). The groups did not differ in regard to stage at presentation, histologic subtype, tumor grade, nodal involvement, or hormone receptor positivity. More than 84% of patients who initiated systemic chemotherapy, regardless of HIV status, completed it without serious toxicity. Among HIV-positive patients receiving chemotherapy, the mean baseline CD4 cell count was 477 cells/µL (standard deviation, 160 cells/µL), and the mean nadir was 333 cells/µL (standard deviation, 166 cells/µL). Conclusion HIV-infected women were younger at breast cancer diagnosis than HIV-negative women but otherwise similar in phenotype and completion of chemotherapy. Longer term follow-up is needed to evaluate the effects of HIV, antiretroviral therapy, and chemotherapy on the survival and quality of life of patients with breast cancer.
Knockdown of TC-1 enhances radiosensitivity of non-small cell lung cancer via the Wnt/β-catenin pathway
Authors: Wu Dapeng , Li Lei , Yan Wei 
Published: March 2016

ABSTRACT
Thyroid cancer 1 (TC-1, C8ofr4) is widely expressed in vertebrates and associated with many kinds of tumors. Previous studies indicated that TC-1 functions as a positive regulator in the Wnt/β-catenin signaling pathway in non-small cell lung cancer (NSCLC). However, its exact role and regulation mechanism in radiosensitivity of NSCLC are still unclear. The expression level of TC-1 was measured by qRT-PCR and western blot in NSCLC cell lines. Proliferation and apoptosis of NSCLC cells in response to TC-1 knockdown or/and radiation were determined by MTT assay and flow cytometry, respectively. The activation of the Wnt/β-catenin signaling pathway was further examined by western blot in vitro and in vivo. Compared to TC-1 siRNA or radiotherapy alone, TC-1 silencing combined with radiation inhibited cell proliferation and induced apoptosis in NSCLC cell lines by inactivating of the Wnt/β-catenin signaling pathway. Furthermore, inhibition of the Wnt/β-catenin signaling pathway by XAV939, a Wnt/β-catenin signaling inhibitor, contributed to proliferation inhibition and apoptosis induction in NSCLC A549 cells. Combinative treatment of A549 xenografts with TC-1 siRNA and radiation caused significant tumor regression and inactivation of the Wnt/β-catenin signaling pathway relative to TC-1 siRNA or radiotherapy alone. The results from in vitro and in vivo studies indicated that TC-1 silencing sensitized NSCLC cell lines to radiotherapy through the Wnt/β-catenin signaling pathway.
Power through standards: The Federal Conference for Outcome Measurement and Benefit Assessment of Chronic Wounds
Authors: Mayer A. , Heyer K. , Storck M. , Debus E. S. , Augustin M. 
Published: March 2016

Summary
Background When concerning documentation and follow up measurement for chronic wounds, uniform standards are a vital precondition for further development of care in Germany. The Federal Consensus Conference “Outcome Measurement and Benefit Assessment for Chronic Wounds” has taken action and has approved systematic recommendations including small data records since 2013.
Aim In the following review rationales, objectives, methods and action outcomes of the Federal Consensus Conference are summarized.
Results Experts from more than 25 different scientific expert associations, professional associations, organizations specialized in care, representatives of statutory health insurance companies as well as the Federal Ministry of Health participated in the consensus formation. From 2013–2015 a total of eight consensus meetings as well as six online consensus enquiries were agreed upon. These entailed a) the relevant subject areas for consensus formation, b) the necessary standards for wound documentation, c) recommendations concerning the enquiries on quality of life for people with chronic wounds, d) recommendations for minimal clinically relevant differences, e) standards on utilization of secondary data and f) recommendations for health-economic analytics of ulcus cruris. The first four publications concerning this topic were finalized.
Conclusions The combination of personal attendance meetings and online enquiries with a broad panel of experts has proved to be an efficient tool for consensus formation regarding the documentation criteria and outcome criteria for chronic wounds using the example of ulcus cruris. The present results are subject of an active implementation in 2016/2017 and at the same time provide a chance for an improved process- and result quality concerning nationwide care.
Yoga as palliation in women with advanced cancer: a pilot study
Authors: Carr Tracey , Quinlan Elizabeth , Robertson Susan , Duggleby Wendy , Thomas Roanne , Holtslander Lorraine 
Published: March 2016

Objective: The purpose of this pilot study was to investigate the palliative potential of home-based yoga sessions provided to women with advanced cancer. Method: Personalised 45-minute yoga sessions were offered to three women with advanced cancer by an experienced yoga teacher. Each woman took part in a one-to-one interview after the completion of the yoga programme and was asked to describe her experiences of the programme's impact. Results: The personalised nature of the yoga sessions resulted in similar positive physical and psychosocial effects comparable to those demonstrated in other studies with cancer patients. Participants described physical, mental, and emotional benefits as well as the alleviation of illness impacts. The enhancement of mind-body and body-spirit connections were also noted. Conclusion: Personalised home-based yoga programmes for people with advanced cancer may produce similar benefits, including palliation, as those institutionally-based programmes for people with non-advanced cancer.
Reconstruction of neglected developmental dysplasia by total hip arthroplasty with subtrochanteric shortening osteotomy
Authors: Atilla Bülent 
Published: March 2016

Patients with neglected developmental dysplasia (DDH) face with early osteoarthritis of the hip, limb length inequality and marked disability while total hip reconstruction is the only available choice. DDH has severe morphologic consequences, with distorted bony anatomy and soft tissue contractures around the hip. It is critical to evaluate patients thoroughly before surgery. Anatomic reconstruction at the level of true acetabulum with uncemented implant is the mainstay of treatment. This requires a subtrochanteric shortening osteotomy, which can be realised using different osteotomy and fixation options. Although a demanding technique with a high rate of related complications, once anatomic reconstruction of the hip is achieved, patients have a remarkably good functional capacity and implant survival during long follow-up periods. Cite this article: Atilla B. Reconstruction of neglected developmental dysplasia by total hip arthroplasty with subtrochanteric shortening osteotomy. EFORT Open Rev 2016;1:65–71. DOI: 10.1302/2058-5241.1.000026.
Avaliação da rotulagem nutricional e das características físico-químicas e microbiológicas de diferentes marcas de leite pasteurizado e leite UHT
Authors: Weschenfelder Simone , Paim Marcelo Pinto , Gerhardt Carin , Wiest José Maria 
Published: March 2016

O objetivo do estudo foi verificar se diferentes marcas de leite pasteurizado e leite UHT integral atendem aos parâmetros de rotulagem e ao regulamento técnico de identidade e qualidade estabelecido pela legislação brasileira. Foram avaliadas dez marcas de leite integral, sendo duas de leite pasteurizado e oito de leite UHT. Quanto à rotulagem, todas as marcas apresentaram conformidade em relação aos parâmetros exigidos pela legislação. Uma marca de leite pasteurizado e três de leite UHT não estavam em conformidade em pelo menos dois, dos cinco lotes avaliados para parâmetros como percentual de gordura, extrato seco desengordurado, peroxidase e contagem de micro-organismos mesófilos aeróbios estritos e facultativos viáveis. Os resultados encontradosapontam que, em quatro das dez marcas avaliadas, existe a necessidade de maior monitoramento das etapas de beneficiamento do leite, uma vez que os alimentos industrializados oferecidos à população devem atender aos parâmetros estabelecidos pela legislação, sendo sinônimos de qualidade e segurança para quem os consome.
Penggunaan Accelerometer MMA7361 sebagai Alternatif Pengukuran Lendutan pada Jembatan Secara Nirkabel Berbasis ATmega32
Authors: Syaryadhi Mohd , Hasibuan Purwandy , Suhardi Suhardi 
Published: March 2016

A bridge is planned and built with a certain capability against vehicles through it. The vehicles movement causes vibration and vertical deflection on certain parts of the bridge. If the vibration occurs continuously in a great value, then the bridge will be damaged sooner than had been planned. This research reports a design of a vertical deflection measuring system prototype on bridge, employing an accelerometer MMA7361 sensor which is controlledby ATmega32. The system was tested by manually loading the trial bridge with 1 m of length. The loading deflects down the bridge to maximum 15 cm from the reference point. Sensor readout data was sent wirelessly using ZigBee real time to computer in a graphical display for easy analysis. The research give an alternative method in vertical deflection measuring on the bridge that can be utilized by stakeholder in policy decision.
A construção da tenda ficcional em Léguas da promissão de Adonias Filho
Authors: Figueiredo Maria do Carmo Lanna 
Published: March 2016

Resumo: Este trabalho é a re-estruturação de uma parte da dissertação de Mestrado, "Léguas da Promissão: o encantatório a serviço da narrativa'", apresentada ao Curso de Pós-Graduação da Faculdade de Letras da Universidade Federal de Minas Gerais em 1980, onde se procurou mostrar que é a partir do tema da violência e para escapar a ela que a ficção se organiza. O ensaio focaliza a narrativa como um jogo em que a utilização de elementos encantatórios é especialmente significativa, destacando-se como criadores destes recursos o mito, o rito, o folclore, a música, o ponto de vista das narrativas entre outros.Résumé: Dans l'analyse de Léguas da Promissão, ensemble de nouvelle d'Adonias Filho, nous essayons de détacher la symbolique de l'espace romanesque à travers l'étude du rite, du mythe, du folklore, du théatre et de la musique. La violence, toujours présente dans l'espace romanesque de les nouvelles, est considerée comme point de départ pour etablir la structure du texte. Nous cherchons à montrer que c'est à partir de la violence et pour lui échapper que la fiction s'organise, une fiction qui a la nature d'un jeu, où l'utilisation des éléments de sorcellerie esttellement significative que nous pourrions dire que dans le recueil Léguas da Promissão, "l'incantatoire est au service du récit."
Procedimentos narrativos em "os sinais da agonia": vozes e modos da enunciação
Authors: Marques Reinaldo Martiniano 
Published: March 2016

Resumo: O presente trabalho constitui parte de um capítulo da dissertação apresentada para a obtenção do grau de Mestre em Literatura Brasileira na Faculdade de Letras da UFMG, em outubro de 1984, sob o título "Os sinos da agonia: técnica narrativa e consciência trágica na ficção de Autran Dourado". Aqui pretende-se evidenciar alguns procedimentos da técnica narrativa autraniana em Os sinos da agonia, particularmente o tratamento concedido às vozes da narrativa e aos modos do narrar, recorrendo-se a uma analogia esclarecedora com a narrativa cinematográfica.Résumé: Ce travail constitue une partie d'un chapitre de ma dissertation, présentée en vue de ma maitrise en Litterature Brésilienne, faite à la Faculté des Lettres de l'Université Fédérale de Minas Gerais. em octobre 1984, sous le titre: "Os sinos da agonia: technique narrative et conscience tragique dans l'oeuvre de fiction d'Autran Dourado". Nous avons comme but de méttre en évidence quelques procédés de technique narrative chez Autran Dourado dans Os sinos da agonia, tout particulièrement le traitement donné aux du pécit et aux façons de raconter, en nous aidant pour cela d'une analogie très éclairante faite avec le récit cinématographique.
AFRICA. Un continente con oportunidad y futuro
Authors: Nonell Torres Pedro , Acuña Barrantes Henry 
Published: March 2016

<p>Este documento tiene como propósito general, presentar las conductas, de personajes destacados y sus creencias religiosas del continente africano, se exteriorizan algunos hechos relativos al comercio intra-africano y se destacan las características específicas de la estructura empresarial entre los países de África que deberán tenerse en cuenta para promover ese comercio y la incursión de países de la BRICS; fue perfilado bajo el paradigma cualitativo y el enfoque hermenéutico. Se utilizó el método documental y descriptivo; el primero, por la consulta realizada a diferentes documentos científicos en internet; y el segundo porque de la información encontrada en la web se extrajo, describió e interpretó lo más trascendente de determinadas personalidades y sus dogmas (Cristiana, católica, ortodoxa, protestante, Islámica, Musulmana sunita, etc.) a su vez, se evidencian las oportunidades y desafíos de este territorio </p>
Left Behind By the Alter: Why Queers and Sociologists Need Materialist Feminism
Authors: Edwards Monica 
Published: March 2016

<p class="FrontMatterbody">The United States marriage rights movement just culminated in July 2015 with the Supreme Court declaring same-sex marriage constitutional. The mainstream — the mainstream media and the mainstream LGBT rights movement — all applaud this trajectory, with no attention to those who get left behind in marriage politics. In this paper, I will argue that same-sex marriage is in need of a materialist feminist analysis. I will critique my discipline — Sociology — for failing to adequately theorize same-sex marriage as a key component of the 21<sup>st</sup> Century landscape of the capitalist mode of production. I will also critique the mainstream LGBT rights movement and the media attention given same-sex marriage for their lack of attention to the classed relations embedded in marriage rights. A materialist feminist analysis will allow us to see that there’s still a need for a larger, more emancipatory sexual politics. </p>
Social Science and Social Struggle: Understanding the Necessary Confluence of Scholarship and Political Commitment
Authors: Clow Michael 
Published: March 2016

<p>Social scientists and historians are wary to acknowledge that political commitments play a part in their explanations of society. But we all know they do. Are we poor scientists? Not according to the Edinburgh School, which argues all successful scientific theories are but practical knowledge, shaped by the encounter of human purpose and empirical world. Practical knowledge always involves the uncertain, trial and error application of the intellectual resources drawn from exemplary solutions to new situations. Praxis <em>is</em> the only valid path to knowledge. But no matter how successful, practical knowledge is a theoretically and empirically limited ‘working knowledge' which cannot produce sure understanding of the generative processes producing what we see. What distinguishes studies of society from those of Nature is that the political purposes of conflicting scholarly traditions are so deeply and manifestly divergent. </p> <p> </p> <p>Implications? Above all we should be skeptical about any strong claims to theoretical certainty, on our part or by others. Dogmatism and sectarianism are epistemologically untenable in the Edinburgh view. Scientific debate would be advanced if we were as open about our political orientations as we are enjoined to be about research design and methodology. And demanded the same of others. This may be possible across ‘camps' in the same tradition and even ideological barriers, where goodwill prevails. In the public sphere the Edinburgh perspective suggests the shifting of the grounds of debate and the framing/reframing of issues requires a tacit recognition that social knowledge is shaped by its political purposes and cannot simply be ‘the facts m'am, just the facts.'</p>
Vigas de pino silvestre sometidas a flexión: influencia de defectos y singularidades = Wild pine beams subjected to bending: influence of defects and singularities
Authors: Rosa Pilar de la , Cobo Alfonso , González Maria De las Nieves 
Published: March 2016

ResumenEn este trabajo se realiza un estudio experimental del comportamiento de dieciocho vigas de madera aserrada para uso estructural, de dimensiones 155x75x1090mm. La madera empleada ha sido de pino silvestre de Valsaín. Los ensayos se han realizado en el Laboratorio de Materiales de Construcción de la Escuela Técnica Superior de Edificación de Madrid. El objetivo del trabajo es el análisis del comportamiento a flexión de las piezas ensayadas teniendo en cuenta de los defectos y singularidades que presentan, realizando un estudio de la influencia de éstos. Se han ensayado dieciocho piezas en total, de las cuales nueve se colocaron en posición plana y las otras nueve de canto. Antes de proceder a los ensayos, la muestra ha sido clasificada según la norma UNE 56544 de clasificación visual de la madera aserrada para uso estructural, determinándose la calidad estructural de cada pieza y la clase resistente teniendo en cuenta que la especie de la madera es pino silvestre. Se identifican las singularidades y defectos que presenta cada una de las piezas y se mide la humedad, el peso y dimensiones de éstas. En las conclusiones se presentan los resultados del análisis realizado, comparando los datos de los ensayos con las características de las piezas, determinando la influencia de la presencia de defectos y las características de las piezas con sus propiedades mecánicas. AbstractThis paper presents an experimental study of the behavior of 18 timber beams for structural use of 155x75x1090mm dimensions. The origin of the wood is Valsaín sawmill. The tests were performed at the Laboratory of Construction Materials at the University School of Technical Architecture. The objective of this work is the analysis of flexural behavior of test pieces according to the defects and singularities, carrying out an analysis of their influence. 18 pieces have been tested, of which 9 were placed in a flat position, and the other 9 were placed in edge position. Before testing, the samples were classified according to UNE 56544 visual grading of sawn timber for structural use, determining the structural quality of each piece and the strength class. Singularities and defects found in each one of the pieces, moisture, weight and dimensions are measured and identified. The results of the analysis are presented in the conclusions, comparing the test data with the characteristics of the beams, determining the influence of the presence of defects and the characteristics of the timber beams with resistance in tests.Index Terms—
Estudio de la Gestión de la Seguridad y Salud en el sector construcción valenciano = Study of Safety and Health Management in the construction sector of Valencia
Authors: Fuentes-Barguesa José Luis , González-Cruz María Carmen , González-Gaya Cristina , García-Arambarrid Naiara , Díaz de Mera-Sánchez María Prado Prador 
Published: March 2016

ResumenLa construcción es un sector que presenta un alto nivel de siniestrabilidad debido a sus características propias (alto componente de mano de obra y que se desarrolla al aire libre) y por sus características organizativas, como los ritmos de trabajo, las metodologías de ejecución y la elevada subcontratación. La gestión de la Seguridad y Salud es un factor determinante a la hora de obtener mejoras en la ejecución de los trabajos y menores tasas de accidentes. En este trabajo se realiza un estudio del nivel actual de gestión de la seguridad y salud en el sector construcción en Valencia (España) a partir de una encuesta realizada a técnicos con experiencia en el sector. Los principales resultados obtenidos son que el tamaño de la empresa es un factor clave para la seguridad y salud, tanto en los aspectos de formación como en la gestión de la documentación de Seguridad y Salud. Los resultados muestran también cómo a pesar del tiempo transcurrido desde las últimas aportaciones normativas, tales como el Libro de Subcontratación o el Registro de Empresas Acreditadas, las empresas tienen un alto desconocimiento de la misma. AbstractConstruction is a sector with a high accident rate due to its own characteristics (high component of labor and develops outdoor) and its organizational characteristics as working patterns, methods of implementation and higher outsourcing. Management of Health and Safety is a determining factor in obtaining best execution of work and lower rates of accidents. This paper presents a study of the current level of Health and Safety Management in the construction sector in Valencia (Spain) from a survey of a group of technicians with experience in the sector. The main results are the size of the company is an important key to health and safety, both in terms of training as in the management of documentation. It also reflects how, despite the time elapsed since the latest regulations, such as the Book of Outsourcing or Accredited Companies Registry, companies have a high rate of ignorance.