bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimating rate of lung function change using clinical spirometry data
Authors: Balasubramanian Aparna , Cervantes Christopher , Gearhart Andrew S , Putcha Nirupama , Fawzy Ashraf , McCormack Meredith C , Singh Anil , Wise Robert A , Hansel Nadia N 
Published: October 2024

RationaleIn chronic obstructive pulmonary disease (COPD), accurately estimating lung function from electronic health record (EHR) data would be beneficial but requires addressing complexities in clinically obtained testing. This study compared analytic methods for estimating rate of forced expiratory volume in one second (FEV1) change from EHR data.MethodsWe estimated rate of FEV1change in patients with COPD from a single centre who had ≥3 outpatient tests spanning at least 1 year. Estimates were calculated as both an absolute mL/year and a relative %/year using non-regressive (Total Change, Average Change) and regressive (Quantile, RANSAC, Huber) methods. We compared distributions of the estimates across methods focusing on extreme values. Univariate zero-inflated negative binomial regressions tested associations between estimates and all-cause or COPD hospitalisations. Results were validated in an external cohort.ResultsAmong 1417 participants, median rate of change was approximately −30 mL/year or −2%/year. Non-regressive methods frequently generated erroneous estimates due to outlier first measurements or short intervals between tests. Average change yielded the most extreme estimates (minimum=−3761 mL/year), while regressive methods, and Huber specifically, minimised extreme estimates. Huber, Total Change and Quantile FEV1slope estimates were associated with all-cause hospitalisations (Huber incidence rate ratio 0.98, 95% CI 0.97 to 0.99, p<0.001). Huber estimates were also associated with smoking status, comorbidities and prior hospitalisations. Similar results were identified in an external validation cohort.ConclusionsUsing EHR data to estimate FEV1rate of change is clinically applicable but sensitive to challenges intrinsic to clinically obtained data. While no analytic method will fully overcome these complexities, we identified Huber regression as useful in defining an individual’s lung function change using EHR data.
Feet-heating and calf-heating have opposing effects on glucose tolerance and heart rate variability: a randomized, controlled, crossover trial
Authors: Sanchez Gabriele , Prince Dena , Glasser Shelby , Buono Michael , Kressler Jochen , Moore Jeff M. 
Published: October 2024

Heat exposure’s effect on glucose tolerance depends on the amount of body exposed, likely relating to autonomic nervous system balance. We assessed how partial-body heat exposure at two different levels of the lower extremities affects glucose tolerance and autonomic nervous system balance, measured via heart rate variability. We hypothesized feet-heating would improve glucose tolerance without affecting heart rate variability, while calf-heating would worsen glucose tolerance and decrease heart rate variability compared to a thermoneutral control condition. In a randomized, controlled, crossover trial, healthy participants’ ( N = 31, 23(3) years, 45% male) glucose tolerance was measured in (A) thermoneutral; (B) feet-heating; and (C) calf-heating conditions. Every 30 min for 2 h, blood glucose, heart rate, heart rate variability, tympanic temperature, thermal comfort scores, and blood pressure were measured. There were significant interactions between condition and time for blood glucose ( F (4.6,72.6) = 2.6, p = 0.036), heart rate ( F (3.4, 54.5) = 3.5, p = 0.017), heart rate variability ( F (4.3,63.2) = 7.5, p < .0001), tympanic temperature ( F (8, 268) = 2.4, p = 0.014), and thermal comfort scores ( F (8, 248) = 22.1, p < 0.0001). Calf-heating increased 90 min glucose (+12 (95% confidence interval, CI: 3–21) mg/dL, p = 0.013) and decreased heart rate variability throughout (mean decrease: 13%–22%, p < 0.007), while feet-heating lowered 90 min glucose (−7 (95% CI: −16 to +1) mg/dL, p = 0.090) without affecting heart rate variability ( p = 0.14–0.99). Blood pressure and body temperature were similar between conditions, but heart rate and thermal comfort scores increased with heating. Calf-heating worsens, while feet-heating may improve, glucose tolerance. Changes in heart rate variability coincided with changes in glucose tolerance despite unchanged body temperature. Whether heart rate variability can be used to monitor autonomic nervous system balance during heating to optimize its acute effect on glycemic indices should be further explored.
The Bioprotective Effects of Marigold Tea Polyphenols on Obesity and Oxidative Stress Biomarkers in High‐Fat‐Sugar Diet‐Fed Rats
Authors: Alsuwayt Bader , Iftikhar Neelam , Hussain Abdullah Ijaz , Ahmad Ashfaq , Zafar Irsa , Khanam Arifa , Tan Wen-Nee , Nahar Lutfun , Almuqati Afaf F. , Haji Esraa Mohammad , Almutairy Ali F. , Sarker Satyajit D. 
Published: October 2024

Background: The research is aimed at exploring the potential of marigold petal tea (MPT), rich in polyphenol contents, against oxidative stress and obesity in a rat model following a high‐fat‐sugar diet (HFSD).Methods: The MPT was prepared through the customary method of decoction and was subjected to analysis for its polyphenol composition using reversed‐phase high‐performance liquid chromatography (RP‐HPLC). Two specific doses of MPT, namely, 250 and 500 mg/kg body weight (BW), were chosen for the study—referred to as MPT‐250 and MPT‐500, respectively.Result: The main phenolic acids and flavonoids identified in MPT, with concentrations exceeding 10 mg/100 mL of tea, included catechin, rutin, salicylic acid, gallic acid, sinapic acid, chlorogenic acid, cinnamic acid, and ellagic acid. The total phenolic (TP) and total flavonoid (TF) contents in MPT were measured to be 5.53 and 7.73 mg/g, respectively. Additionally, MPT demonstrated a 57.2% scavenging capacity with 2,2‐diphenyl‐1‐picrylhydrazyl radical. Notably, the administration of a higher dose (MPT‐500) showed a significant reduction in body mass index (BMI) and a 51.24% reduction in the rate of increase in BW compared to the HFSD group. The findings indicated that all the treatment groups, that is, orlistat treatment (OT), MPT‐250, and MPT‐500 groups, experienced reduced levels of serum total cholesterol (TC), triglyceride (TG), and markers of lipoproteins in contrast to the HFSD group. Moreover, MPT helped restore the levels of malondialdehyde (MDA), superoxide dismutase (SOD), and reduced glutathione (GSH), thereby demonstrating its potential in combating oxidative stress. The MPT‐500 group also displayed decreased liver and kidney weights and an improved atherogenic index when compared to the HFSD group.Conclusion: The results clearly indicate that a high dosage of MPT showed antiobesity activity which was comparable to the same effects produced by the conventional drug orlistat.
NOise Reduction with DIstribution Corrected (NORDIC) principal
component analysis improves brain activity detection across rodent and human
functional MRI contexts
Authors: Chan Russell W. , Hamilton-Fletcher Giles , Edelman Bradley J. , Faiq Muneeb A. , Sajitha Thajunnisa A. , Moeller Steen , Chan Kevin C. 
Published: October 2024

Abstract
NOise Reduction with DIstribution Corrected (NORDIC) principal component analysis (PCA) has been shown to selectively suppress thermal noise and improve the temporal signal-to-noise ratio (tSNR) in human functional magnetic resonance imaging (fMRI). However, the feasibility to improve data quality for rodent fMRI using NORDIC PCA remains uncertain. NORDIC PCA may also be particularly beneficial for improving topological brain mapping, as conventional mapping requires precise spatiotemporal signals from large datasets (ideally ~1 hour acquisition) for individual representations. In this study, we evaluated the effects of NORDIC PCA compared with “Standard” processing in various rodent fMRI contexts that range from task-evoked optogenetic fMRI to resting-state fMRI. We also evaluated the effects of NORDIC PCA on human resting-state and retinotopic mapping fMRI via population receptive field (pRF) modeling. In rodent optogenetic fMRI, apart from doubling the tSNR, NORDIC PCA resulted in a larger number of activated voxels and a significant decrease in the variance of evoked brain responses without altering brain morphology. In rodent resting-state fMRI, we found that NORDIC PCA induced a nearly threefold increase in tSNR and preserved task-free relative cerebrovascular reactivity (rCVR) across cortical depth. NORDIC PCA further improved the detection of TGN020-induced aquaporin-4 inhibition on rCVR compared with Standard processing without NORDIC PCA. NORDIC PCA also increased the tSNR for both human resting-state and pRF fMRI, and for the latter also increased activation cluster sizes while retaining retinotopic organization. This suggests that NORDIC PCA preserves the spatiotemporal precision of fMRI signals needed for pRF analysis, and effectively captures small activity changes with high sensitivity. Taken together, these results broadly demonstrate the value of NORDIC PCA for the enhanced detection of neural dynamics across various rodent and human fMRI contexts. This can in turn play an important role in improving fMRI image quality and sensitivity for translational and preclinical neuroimaging research.
Early Image Processing and Computer Animation in Colorado: Pat Lehman’s Video Vitae in Context
Authors: Pytlinski Deanne 
Published: October 2024

Abstract
In 1976, Pat Lehman screened her experimental video Video Vitae at the New York Women’s Video Festival. Lehman worked in Colorado, where she also started the first video program in the state’s college system. This article examines Video Vitae as an important example of image-processed video and early computer animation in the context of second-wave feminism. The author charts Lehman’s influences and access to the Scanimate computer used to produce Video Vitae, arguing that Lehman’s narrative about a woman’s autonomy is intertwined with her pleasure in the processing of electronic signals.
Our Bodies Demand Their Turn!: Live Synthesizer in Shigeko Kubota’s Riverrun—Video Water Poem
Authors: Robinson Lia 
Published: October 2024

Abstract
Shigeko Kubota presented her seminal multimedia video work Riverrun—Video Water Poem for the feminist performances of Red, White, Yellow, and Black at The Kitchen in New York in December 1972. This article outlines Kubota’s exploration of the mediated production of identity as a networked, social process through live video synthesis. Drawing from discourses surrounding James Joyce’s Finnegans Wake in experimental music and video, Kubota’s distinctive use of live video synthesis and incorporation of sensorial elements in her installation attuned her audience to the multisensory nature of communication as well as the co-constitution of meaning mediated through feedback between artist, audience, and technology. In considering Riverrun as an open work, it is clearer how Kubota resisted singular interpretations, especially readings where the work is reducible to the artist’s identity.
When Image Processing Becomes Image Creation: Gregory Zinman in Conversation with LoVid
Authors: Zinman Gregory , Hinkis Tali , Lapidus Kyle 
Published: October 2024

Abstract
The multidisciplinary artist duo LoVid have been making art that combines analog and digital media, as well as handmade and code-based methods, for nearly a quarter century. Topics discussed in this interview include image processing, generative art, Web3, and sociality in contemporary media art.
Auschwitz and Hiroshima: Günther Anders
Authors: Traverso Enzo 
Published: October 2024

Abstract
Widely translated into several Western languages (with the exception of English), Günther Anders (1902–92) has, in the last two decades, attained the status of a classic figure within twentieth-century critical thought, close to Herbert Marcuse and the Frankfurt School without ever becoming one of its members. This article analyses his intellectual trajectory and his body of work, which includes many articles, essays, short stories, and even a novel. It focuses on his Jewish roots, which made him a paradigmatic representative of the ‘non-Jewish Jew’: a Jew confronted with antisemitism, an internationalist standing before the Jewish tradition. The crucial premises of his original theory, the author emphasises, were Auschwitz and Hiroshima, the extermination of European Jewry, and the atomic bomb. Set out in his most ambitious work, The Outdatedness of Human Beings (Volume 1, 1956; Volume 2, 1980), Anders’ thought appears as a kind of dialectical sublation, from a Marxist perspective, of Heidegger’s philosophy of technique (where technique has replaced human beings as the subject of history), articulated with a radical criticism of Heidegger’s political ontology.
The Psychological Type and Temperament Profile of Ordinands at Cranmer Hall, Durham, 2008–2016
Authors: Cook Christopher C. H. , Francis Leslie J. , McKenna Ursula 
Published: October 2024

Abstract
This study explores the psychological type and temperament profile of 117 male and 80 female ordinands training at Cranmer Hall, Durham, over a nine-year period alongside earlier studies of Church of England stipendiary clergy. The data confirm the prominence of the Apollonian (NF) Temperament accounting for 41% of male and 54% of female ordinands. Among male ordinands there were preferences for extraversion (58%), intuition (70%), feeling (61%), and judging (60%). Among female ordinands there were preferences for extraversion (56%), intuition (64%), feeling (74%), and judging (74%). The implications of these finding are discussed for the future shape of ministry.
Unpacking the Multiplicity of Chineseness: a Case Study of the Guanyin Shrine in Mueang Mae Hong Son, Thailand
Authors: Sriratanaban Suphacha 
Published: October 2024

Abstract
This paper aims to examine the origins and development of the Guanyin Shrine in Mueang Mae Hong Son, Thailand, and to investigate how its construction of Chineseness is informed by various factors at intra-ethnic, local, and national levels. Through ethnographic fieldwork, it was found that the Chineseness embodied in the Shrine is a paradigm encompassing the identities of overseas Chinese from different backgrounds. The Shrine is characterized by its use of universally recognized symbols in Chinese culture, including the selection of Guanyin as the main deity and the creation of unique trademarks using common motifs such as yin-yang and bagua. The Shrine represents a hybridization not only of Chineseness and national identity but also of Chineseness and local identity, as seen through the application of national symbols such as the Thai monarchy and Theravada Buddhism, the ritual of inviting Tai Yai guardian deities, and the procession of ethnic groups during the Annual Celebration.
Parliaments in Europe – International Conference on the Occasion of Day of Parliamentarianism
Authors: Tóth László , Verebélyi Viktória 
Published: October 2024

Abstract
The Centre for Parliamentary Research at the Ferenc Deák Faculty of State and Law of Széchenyi István University organized between 9–10. May 2024 for the ninth time this year an overview of Hungarian and international parliamentary research within the framework of the Day of Parliamentarianism conference series. On the first day of the two-day international conference “Parliaments in Europe”, researchers shared their research results in Hungarian, while on the second day, attendants could listen to lectures in English.
‘That Kind of Role Models it!’ Dynamics of Intergenerational Reinforcement and Disruption of Stigma Towards People Who Use Drugs
Authors: Flam-Ross Juliet Miko , Zampini Giulia Federica 
Published: October 2024

Background Stigma towards people who use drugs (PWUD) is a dangerous phenomenon with far-reaching effects. Research shows that parents play a powerful role in the shaping of their children's views of people with mental illness, but no similar research exists to investigate the shaping of views towards PWUD. This qualitative study explores dynamics of intergenerational reinforcement and disruption of stigma towards PWUD. Methods Semi-structured qualitative interviews were conducted with eight people split equally into two categories: 1) Participant-children: people between 18 and 30 and 2) Participant-parents: people of any age with experience as a parent of a child. Participants had some experience of using drugs or alcohol, but this was not a criterion for selection. Interviews elucidated the influence of parents’ views, opinions, narratives, discussions, and disclosures on views towards PWUD. Interviews included questions about stigma and its intergenerational development. Grounded theory was used to analyze the data. Results Three major themes in theory development were elicited for their role in the reinforcement and disruption of stigma towards PWUD: 1) conflation of drug use with other stigmatized characteristics; 2) the telling of stories around problematic drug use; and 3) the use of secrecy or disclosure of personal drug use. Conclusion The results of the study provide an understanding of the dynamics of stigma reinforcement and disruption. Each of the actions described in the themes can work towards either reinforcing or disrupting stigma.
The Academic Impact of Enrollment in International Baccalaureate Diploma Programs: A Case Study of Chicago Public Schools
Authors: SAAVEDRA ANNA ROSEFSKY 
Published: October 2024

Background: In schools accredited as “IB World Schools ” by the International Baccalaureate Organization (IBO), teachers use IB curriculum and pedagogy to teach a range of courses that are intended to prepare IB-enrolled students for college. Over the past 18 years, the number of U.S. schools that implement IB programs has increased nearly tenfold, from 133 in 1994 to 1,390 in 2013. Despite the IB program’s rapid expansion, little is known about whether IB enrollment causally improves students’ academic outcomes, including their high school academic achievement, probability of high school graduation and/or subsequent probability of college enrollment. Purpose: This study examines whether enrollment in the IB Diploma Program increases students’ academic achievement as measured by their composite ACT college admissions examination scores, probability of high school graduation, and probability of college enrollment, and whether the estimates differ by gender. Setting, Population, & Data: This study uses data on the demographic characteristics, IB enrollment status, ACT scores, high school graduation status and college enrollment status of 20,422 students attending 13 Chicago Public Schools (CPS) high schools from 2002-2008. Data sources include the CPS and the National Student Clearinghouse. Research Design: The analytic strategy is to first assume students are selected into the IB Diploma Program based on their observed characteristics, and then to use a propensity score approach to estimate the impact of IB enrollment on three measures of students’ academic success. The second step, following Rosenbaum (2002), is to test the sensitivity of the estimates to different levels of selection bias. Results: This study shows that IB enrollment increases students’ academic achievement, probability of high school graduation and probability of college enrollment. Though selection bias may contribute to overstating the propensity score estimates, the conclusion from the sensitivity analyses is that it is unlikely that this internal-validity challenge negates the principal finding. All estimates are greater for boys than for girls. Calculations demonstrate that the IB Diploma Program is a cost-effective way to increase high school graduation rates. Conclusions: The results are valuable for three reasons. First, they provide valuable information with which to make decisions about future investments in IB. Second, they contribute to knowledge of the means through which to improve high school education for disadvantaged urban youth. Finally, the results suggest that IB enrollment is especially beneficial for boys, for whom the probability of graduating from high school and enrolling in college—in CPS and at the national level—is substantially less than for girls.
Financial decision dynamics: Environmental, social, and governance factors and managerial choices in emerging markets
Authors: Wasan Pratibha , Mulchandani Kalyani 
Published: October 2024

This study examines the linkage between the ESG performance of firms and managerial decision-making. It uses 8 years of ESG performance data of 110 Indian firms collected from the Thomson Reuters database. The study finds that high ESG performance mitigates a firm’s cost of debt more than equity cost. Furthermore, increases in ESG performance are associated with higher capital expenditures, lower investment cash flow sensitivity, higher cash holdings, and lesser payout of increased cash flows to shareholders. The findings are in sync with the Slack resources view, suggesting that the requirement of financial Slack for ESG-related innovations and risk-bearing is large and impacts the major managerial decisions of firms. While the effects of environmental and social performance on these decisions are similar to that of the composite ESG performance, governance performance shows an independent impact on the payout decisions of firms. The Granger Causality test reveals a bi-directional association between debt issues and ESG performance. The main results obtained from the multiple panel regressions are robust to additional tests involving lead-lag analysis. The overall findings of this study highlight the importance of ESG performance screening in the managerial decision-making process of investors who would not like to risk growth potential for a short-term increase in dividends.
Association between motor neuron disease and HIV infection: A systematic review of case reports
Authors: Fernandes João Paulo Moreira , Garcia Leonardo Peixoto , Gouhie Felipe Araújo , Pereira Raquel Campos , Santos Diogo Fernandes dos 
Published: October 2024

Background Motor neuron disease (MND) is a well-known group of neurodegenerative diseases, with amyotrophic lateral sclerosis (ALS) being the most common form. Since 1985, a possible association between MND/ALS and HIV infection has been described. Methods We performed a systematic review of case reports and case series involving people living with HIV with MND/ALS through PubMed, Bireme, Embase, and Lilacs databases. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for Case Reports. Results We analyzed 36 articles presenting 88 cases. The mean age was 41.6 years. Antiretroviral therapy (ART) was used by 89.8% and riluzole by 16.9%. First signs and symptoms were similarly present on cervical/upper (25%) and lumbosacral/lower limbs (23.9%), mostly with fasciculations (69.8%) and hyperreflexia (58.8%). MND had a progressive course in 32.9% patients and a clinical improve in 54.6% following ART. The mean survival of the 32 patients who died was 12.3 months and the mean survival of the living patients was 62 months. Respiratory failure was the main cause of death (35.7%). Conclusions MND/ALS may present differently in the people living with HIV as a rapidly progressive disease in younger people but with the potential to improve weakness and survival through antiretroviral therapy.