bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel 3D Printed Biomaterials Based on Fish Scale Collagen and Plant Extracts and Its Hemostatic Efficacy
Authors: Tran Hoang Dung , Thai Hoang , Thuy Nguyen Duong Thi , Thi Vu Mai , Tuan Nguyen Anh , Xuan Nguyen Thai , Cam Ngo Quyen Thi , Thuy Nguyen Chinh 
Published: September 2024

AbstractThis study focused on 3D printing‐preparation of novel biomaterials based on fish scale collagen and the following plant extracts: Eclipta alba L. Hassk leaf (EA), Piper betle L. leaf (PB), Perilla frutescens L. Britt leaf (PF), and Styphnolobium japonicum L. Schott flower bud (SJ). The characterizations of the obtained biomaterials were analyzed using infrared spectroscopy and stereo microscopy. Additionally, assessments of the biomaterials were conducted on the water contact angle, simulated body fluid contact angle, scratch resistance, color changes, and swelling degree in simulated body fluid. Furthermore, in‐vitro blood clotting time and the anti‐inflammatory ability of these biomaterials were also performed. The results indicated that the plant extracts contributed to modifying collagen, significantly improving the scratch resistance and water contact angle of the collagen/plant extract biomaterials. The plant extracts were dispersed consistently with the collagen matrix, impacting the vibrations of specific functional groups of collagen. Collagen/plant extract dressings exhibited great biocompatibility and anti‐inflammatory. The in‐vitro tests demonstrated that the ethanol EA extract notably enhanced the hemostatic effectiveness of collagen, suggesting the potential of collagen/plant extract biomaterials in hemostatic applications.
Zincophile Zn2+ Conductor Regulation by Ultrathin Nano MoO3 Coating for Dendrite‐Free Zn Anode
Authors: Lin Haisheng , Cai Shujuan , Li Lanyan , Ma Zhongyun , Wang Xianyou , Liang Shuquan , Fang Guozhao , Xiao Manjun , Luo Zhigao 
Published: September 2024

AbstractAqueous battery with nonflammable and instinctive safe properties has received great attention. However, issues related to Zn anode such as side reactions and rampant dendrite growth hinder the long‐term circulation of AZMBs. Herein, an ultrathin(35 nm) MoO3 coating is deposited on the Zn anode by means of vacuum vapor deposition for the first time. Due to the peculiar layer structure of MoO3, insertion of Zn2+ in ZnxMoO3 acts as Zn2+ ion conductor, which regulates Zn2+ deposition in an ordered manner. Additionally, the MoO3 coating can also inhibit the hydrogen evolution and corrosion reactions at the interface. Therefore, both Zn//MoO3@Cu asymmetric battery and Zn symmetric battery cells manage to deliver satisfactory electrochemical performances. The symmetric cell assembled with MoO3@Zn shows a significant long cycle life of more than 1600 h at a current density of 2 mA cm−2. Meanwhile, the MoO3@Zn//Cu asymmetric cell exhibits an ultrahigh Zn deposition/stripping efficiency of 99.82% after a stable cycling of 650 h at 2 mA cm−2. This study proposes a concept of “zincophile Zn2+ conductor regulation” to dictate Zn electrodeposition and broadens novel design of vacuum evaporation for nano MoO3 modified Zn anodes.
Biogeographic, climatic, morphological, cytological and molecular data reveal a new diploid species from China in the genus Xanthocyparis (Cupressaceae)
Authors: Jiang Yu‐Liang , Li Jia‐Liang , Milne Richard Ian , Nguyen Khang Sinh , Han Zhi‐Tong , Huang Yu‐Song , Xu Wei‐Bin , Liu Yan , Mao Kang‐Shan 
Published: September 2024

AbstractThe genus Xanthocyparis was described in 2002 for a new conifer species X. vietnamensis from northern Vietnam, which became well‐known for its rarity. Recently, natural diploid populations were found in a small area of northern Guangxi, China, whereas material from Vietnam plus newly discovered populations from southern Guangxi were determined to be tetraploids. We integrated evidence from multiple data sources to perform a taxonomic evaluation of the two ploidy levels present in Xanthocyparis. Morphometric analyses detected statistically significant differences in cone and leaf characters, whereas microsatellite and transcriptome analyses revealed clear genetic divergence between diploid and tetraploid material. Furthermore, analysis of bioclimatic variables confirmed divergence in ecological niches. Gene trees from homologous sequences indicate that tetraploid material might have arisen via allopolyploidy from the extant diploid material and a third, possibly extinct lineage. Therefore, we recognize and describe a new diploid species from northern Guangxi China: Xanthocyparis guangxiensis.
Non‐invasive blood pressure measurement in conscious rabbits: A comparison of Doppler ultrasonic and oscillometric devices
Authors: González‐González Enrique , González‐Alonso‐Alegre Elisa , Montesinos‐Barceló Andrés , Caro‐Vadillo Alicia 
Published: September 2024

AbstractBackgroundThis study aimed to compare Doppler (the most commonly used technique for non‐invasive indirect blood pressure [NIBP] measurement in rabbits) and oscillometric devices for NIBP measurements in conscious rabbits.MethodsBlood pressure (BP) measurements were obtained for 49 conscious rabbits using the Doppler and oscillometric devices. Each measurement was repeated in triplicate. Three rabbits were excluded from the study because it was not possible to obtain BP measurements using the oscillometric device. The American College of Veterinary Internal Medicine (ACVIM) guidelines were followed to compare the results obtained with the two devices.ResultsA total of 164 systolic BP measurements were obtained with the Doppler device and 182 were obtained with the oscillometric technique. The mean of the three values obtained for each animal with each device was used for statistical analysis. The analysis demonstrated a poor level of agreement between the measurements obtained with the two devices.LimitationsOscillometric devices rely on built‐in software algorithms to perform calculations and produce their measurements. However, the oscillometric devices currently available only have the software for dogs and cats installed. Therefore, these conclusions should be revised when a device with software specifically for rabbits is commercialised.ConclusionsThis study indicates that oscillometric devices should not be used as a substitute for the Doppler technique when measuring BP in rabbits.
The Text and the Work
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractThe author brings out the most important aspects of this vast topic from the perspective of a musician. The text is the primary given for musical interpretation which indicates a hidden meaning. The text is aggressive because it declares what is written in it, and powerless, because everyone can do with it as they please (T. Sodeika). The work is only a promise, since what unfolds within it “does not yet exist” (A. Maceina). The work issues a challenge which expects to be met (H. Gadamer). The said [le dit] does not count as much as saying [le dire] (E. Levinas): for the explanation of musical language, expression is required. The text is not an entity of signs closed in itself, but a space in which lines of semantic impulses are drawn (I. Melnikova). The deep semantics of the text are not what the author was intending to say but what the text itself speaks of (A. J. Greimas): a work says more than is embraced by the creator’s consciousness (A. Maceina). Hermeneutics envisages the restoration of the meaning of the text or the creation of that meaning by a new interpretation which is already that of the interpreter (J. Baranova). Texts exist by way of escaping from the captivity of their signs. Only the interpreted—intoned—musical text becomes a creative work.
Significance and Meaning (the Given and the Goal)
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractIn terms of significance, the text is a sequence of signs, but in terms of meaning, the text appears as a semantic unit (as a creative work). Significance is a reference to what is human; meaning is a reference to what is beyond human (A. Šliogeris). Anything acquires meaning if it refers to something beyond itself (M. K. Cohen). Consciousness is nothing apart from its ideal object, that is, the essence, the eidos (D. Stewart, A. Mickunas). Knowing what you would like to understand is a contribution to the creation of order in one’s actions (R. Brague). In music, intonation can be considered synonymous with meaning since it is only through intonation that the meaning—the idea—is manifested. The self-contained autonomy of the musical code (G. Steiner). Meaning never emerges as a final given thing (J. Kubilius): interpretation, as access to meaning, is a never-ending action. The prefix ex- indicates direction from something: the ex- direction—in the case of expression—is an action moving from the understood meaning to its external manifestation in sound. The grasp of meaning requires a competent relationship with the text of the musical work, founded on knowledge of general and musical culture.
Chamelon : A Delta-Debugger for OCaml
Authors: Valnet Milla , Courant Nathanaëlle , Bury Guillaume , Chambart Pierre , Laviron Vincent 
Published: September 2024

AbstractTools that manipulate OCaml code can sometimes fail even on correct programs. Identifying and understanding the cause of the error usually involves manually reducing the size of the program, so as to obtain a shorter program causing the same error—a long, sometimes complex and rarely interesting task. Our work consists in automating this task using a minimiser, or delta-debugger. To do so, we propose a list of unitary heuristics, i.e. small-scale reductions, applied through a dichotomy-based state-of-the-art algorithm. These proposals are implemented in the free Chamelon tool. Although designed to assist the development of an OCaml compiler, Chamelon can be adapted to all kinds of projects that manipulate OCaml code. It can analyse multifile projects and efficiently minimise real-world programs, reducing their size by one to several orders of magnitude. It is currently used to assist the industrial development of the flambda2 optimising compiler.
Situationsanalyse – Methoden zur Klärung des ethischen Mandates von Pflegekammern
Authors: Kuhn Andrea 
Published: September 2024

ZusammenfassungZur Konzeption einer Programmtheorie ist die Konturierung des komplexen Themenfeldes Ethik in der Pflege in Deutschland im Lichte von Pflegekammern erforderlich. Die Methodologie folgt einem qualitativen Approach, der die strukturierte Eingrenzung und Kartierung der Komplexität ermöglicht. Eine Situationsanalyse bündelt das vorhandene Wissen in zentrale Argumentationsstränge. Zu beachten sind komplexe Faktoren, die die Implementierung von Ethik in Strukturen und Prozesse von Pflegekammern beeinflussen, seien es Normen, Wissensstände, politische Interessen und vieles mehr. Methodisch dient eine fokussierende Scoping Studie als Instrument der Situationsanalyse. Die Ergebnisse laufen im Logic Model Building zusammen. Sie kondensieren die nötigen Bausteine zur Konzeption der Programmtheorie für eine nachhaltige Umsetzung des ethischen Mandats von Pflegekammern in und für die professionelle Pflege.
Advertisements for prescription-free drugs and dietary supplements in the Deutsche Apotheker Zeitung (German Pharmacist Journal)
Authors: Kuschel Kristian , Seifert Roland 
Published: September 2024

AbstractThe Deutsche Apotheker Zeitung (DAZ, German Pharmacist Journal) is an independent pharmaceutical newspaper focusing on science and practice, mainly for the profession of pharmacist. In this study, drug advertising in the DAZ was analysed. To our knowledge, there is little scientific data available on drug advertising in professional journals. We assumed that professional journals provide particularly good background information on the advertised drugs because they are targeted to specialists. All non-prescription medicines and preparations that fall under the Medicines Advertising Law (Heilmittelwerbegesetz, HWG) were studied. The Medicines Advertising Law regulates the legal procedure for advertising medicinal products in Germany. The 167 product advertisements from the 52 issues of 2021 were analysed and checked for compliance with the Medicines Advertising Law. We identified significant deficiencies in compliance with the legislation. These included the lack of mandatory information required by the Medicines Advertising Law, for example the indication of adverse drug reactions and the listing of contraindications. There are very few peer-reviewed references on the efficacy of the advertised preparations. A scientific validation was carried out using the PubMed database, with the result that scientific information was available only for 1/3 of the advertisements. In addition, the appearance and target groups as well as social structures, images and feelings conveyed by the advertising were analysed. This study provides insights into the mechanisms of drug advertising in professional journals, which have not yet been researched to any great extent. Even in professional journals, pharmacological evidence plays a much smaller role than marketing, psychology and traditional social values. It seems that drug manufacturers deliberately ignore the German Medicines Advertising Law to advertise their products in the best possible way. Stricter legal controls should be put in place to prevent this practice and protect consumers from misinformation. This will increase drug safety.
Identification of transformation products from fluorinated lithium-ion battery additives TPFPB and TPFPP: forever chemicals of tomorrow?
Authors: Scholl Juliane , Lisec Jan , Haase Hajo , Koch Matthias 
Published: September 2024

AbstractFluorinated organic compounds (FOCs) represent a class of synthetic chemicals distinguished by their resilient carbon–fluorine bonds, which demonstrate an ability to withstand environmental degradation over an extended period. The integration of FOCs into cutting-edge applications, including lithium-ion batteries (LiBs), presents considerable potential for environmental harm that has not yet been sufficiently addressed. This study focuses on the environmental fate of two fluorinated aromatics, tris(pentafluorophenyl)borane (TPFPB) and tris(pentafluorophenyl)phosphine (TPFPP), given their important role in improving the performance of LiBs. To achieve this, laboratory simulation methods including total oxidizable precursor assay, electrochemistry (EC), Fenton reaction, UV-C irradiation, and hydrolysis were employed. Liquid chromatography and gas chromatography coupled with high-resolution mass spectrometry were used for identification of transformation products (TPs) and prediction of their molecular formulae. Despite the structural similarity between TPFPB and TPFPP, distinct differences in electrochemical behavior and degradation pathways were observed. TPFPB readily underwent hydroxylation and hydrolysis, resulting in a wide range of 49 TPs. A total of 28 TPs were newly identified, including oligomers and highly toxic dioxins. In contrast, TPFPP degraded exclusively under harsh conditions, requiring the development of innovative conditioning protocols for EC. In total, the simulation experiments yielded nine structurally different compounds, including seven previously undescribed, partially defluorinated TPs. This study highlights the potential risks associated with the use of FOCs in LiBs and provides insight into the complex environmental behavior of FOCs.
Graphical Abstract
A system-theoretic assurance framework for safety-driven systems engineering
Authors: Ahlbrecht Alexander , Sprockhoff Jasper , Durak Umut 
Published: September 2024

Abstract
The complexity of safety-critical systems is continuously increasing. To create safe systems despite the complexity, the system development requires a strong integration of system design and safety activities. A promising choice for integrating system design and safety activities are model-based approaches. They can help to handle complexity through abstraction, automation, and reuse and are applied to design, analyze, and assure systems. In practice, however, there is often a disconnect between the model-based design and safety activities. At the same time, there is often a delay until recent approaches are available in model-based frameworks. As a result, the advantages of the models are often not fully utilized. Therefore, this article proposes a framework that integrates recent approaches for system design (model-based systems engineering), safety analysis (system-theoretic process analysis), and safety assurance (goal structuring notation). The framework is implemented in the systems modeling language (SysML), and the focus is placed on the connection between the safety analysis and safety assurance activities. It is shown how the model-based integration enables tool assistance for the systematic creation, analysis, and maintenance of safety artifacts. The framework is demonstrated with the system design, safety analysis, and safety assurance of a collision avoidance system for aircraft. The model-based nature of the design and safety activities is utilized to support the systematic generation, analysis, and maintenance of safety artifacts.
Synthetic libraries of urban landslide simulations to identify slope failure hotspots and drivers across spatial scales and landscapes
Authors: Bozzolan Elisa , Holcombe Elizabeth , Pianosi Francesca , Wagener Thorsten 
Published: September 2024

Abstract
Rainfall-triggered landslides are most deadly in developing countries, and future urban sprawl and climate change could intensify existing risks. In these regions, enhancing efforts in urban landslide risk mitigation and climate change adaptation is crucial. Current landslide probability assessment methodologies struggle to support effective mitigation because they fail to represent local anthropogenic factors (e.g. informal housing) across space and time scales. To meet this challenge, we demonstrated in previous work that hillslope-scale mechanistic models representing such localised changes can be used to create synthetic libraries of urban landslides that account for both data and future scenario uncertainty. Here, we show how these libraries can become an explorative tool for researchers and stakeholders, allowing them to investigate slope stability variations across spatial scales and landscapes. Results highlight, for example, how the main slope instability drivers change according to the location (e.g., upper vs lower catchment), the landcover (e.g. forest vs urban) and the spatial scale analysed (e.g. at hillslope scale slope stability was mostly controlled by water table height, whereas at regional scale by slope geometry). Ultimately, we demonstrate that stochastic analyses can lead to a greater understanding of the system interactions and they can support the identification of mitigation strategies that perform well across spatial scales and uncertain scenarios. These strategies should be prioritised even if future conditions are unknown. This reasoning is shown on a data-scarce region with expanding informal housing. However, the same methodology can be applied to any urban context and with any mechanistic-based model.
Discordant myocardial perfusion defects and coronary artery disease – a multimodality imaging journey in the natural history of cardiac sarcoidosis
Authors: Galafton Andrei , Buechel Ronny R. , Mikulicic Fran , Kaufmann Philipp A. , Giannopoulos Andreas A. 
Published: September 2024

Abstract
Cardiac sarcoidosis is a rare form of systemic sarcoidosis characterized by formation of non-caseating granulomas in the myocardium, leading to heterogeneous manifestations, including conduction disturbances, arrhythmias, and heart failure. Besides myocardial fibrosis and structural myocardial alterations, cardiac sarcoidosis can impact the epicardial and microvascular circulation, causing ischemia and regional microvascular dysfunction. We present a case of cardiac sarcoidosis with atypical initial presentation but with evidence of disease in myocardial perfusion imaging, which was overlooked since it did not correspond to bystander coronary artery disease. Multimodality imaging facilitated diagnosis and offered insights into the regional microcirculation impairment caused by sarcoidosis-induced inflammation.
Supporting the Conversational Behavior of Adolescents with Autism Spectrum Disorders with Self-Monitoring and a Video-Based Supplement
Authors: Ayvazo Shiri , Shmuel Yafit , Bin-Nun Inbar 
Published: September 2024

AbstractIndividuals with autism spectrum disorders (ASD) might demonstrate impairments in initiating and sustaining a conversation and experience conversational challenges such as question-asking and turn-taking. Conversational skills are pivotal for the social functioning of adolescents with ASD. The current investigation aimed to extend the available information on interventions addressing the conversational needs of adolescents with ASD. The research questions were: (a) What is the effect of self-monitoring, supplemented by a video-based model on the conversational skills of adolescent students with ASD? and (b) What is the acceptability of the intervention among the participating adolescents with ASD?. Appropriate conversational behavior of three students with ASD (aged 16–18 years) was assessed using a withdrawal design, during 10-min conversation sessions. Appropriate conversational behavior was defined as a sequence of a turn-taking response (i.e., waiting quietly until the speaker finished talking), followed by a verbal utterance which included (a) making a statement or responding on topic, and/or (b) asking a contextually appropriate “wh”- question. The independent variable consisted of a primary self-monitoring procedure and a daily video-based supplement. Treatment fidelity and treatment acceptability were also assessed. The conversational behavior of all participants consistently improved under the self-monitoring intervention with the video-based supplement. Self-monitoring with a video-based supplement can effectively support the conversational behavior in adolescents with ASD. This information can guide the evaluation and planning of appropriate interventions designed to improve limited conversational behaviors of adolescents with ASD.
Mathematics teacher educators’ navigational expertise when designing multimodal representations of practice: a semiotic analysis
Authors: Schwarts Gil , Herbst Patricio , Chazan Daniel , Buchbinder Orly , Clark Lawrence M. , Wieman Rob , Zahner William 
Published: September 2024

AbstractCritical elements of the expertise of mathematics teacher educators (MTE) can be identified in the artifacts they design for working with prospective teachers (PT), specifically for engaging PT in the double role of practitioners and students of practice. While MTE are increasingly utilizing designed multimodal representations of practice (such as storyboards), theoretical frameworks and methods for analyzing these pedagogical artifacts and the meanings they support are still in early development. We utilize a semiotic framework, expanding systemic functional linguistics to encompass non-linguistic elements, to identify aspects of what we call navigational expertise—which supports PTs in engaging both as practitioners and students of the practice. We view this expertise as tacit knowledge-in-use, enacted through artifact production. The paper demonstrates MTE’s navigational expertise by showing how MTE design storyboards of practice to engage PT as fellow teachers experiencing the lesson taught by a peer and as university students who consider the artifact (including the represented lesson) as an object of study. The framework allows us to identify how MTE’s navigational expertise lies in seamlessly interweaving these two purposes and navigating between them, knowing when, how, and for what purposes to invoke each. Through analysis of storyboards from four MTE in diverse US settings, we uncover some of the nuanced tacit components of navigational expertise, highlighting linguistic and non-linguistic design choices and their potential meanings for transactions with PT.