bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selektive Degeneration dopaminerger Neurone beim Parkinson-Syndrom: die zunehmende Rolle von veränderter Kalziumhomöostase und nukleolärer Funktion
Authors: Parlato Rosanna , Liss Birgit 
Published: December 2017

Zusammenfassung
Morbus Parkinson (MP) ist die zweithäufigste neurodegenerative Erkrankung. Die klassische MP-Motorsymptomatik wird durch einen progressiven Dopaminverlust im Striatum verursacht, bzw. durch den fortschreitenden Verlust von Dopamin-ausschüttenden (DA) Neuronen im Mittelhirn (insbesondere in der Substantia nigra, SN, auch schwarze Substanz genannt). Da die Ursache für den MP immer noch unklar ist, stehen derzeit keine kurativen Therapien zur Verfügung. Es konnten aber eine Reihe von genetischen und umweltbedingten Triggerfaktoren identifiziert werden, die auf einen gemeinsamen, komplexen Pathomechanismus hinweisen, wobei metabolische Dysfunktion und geänderte Genexpression von besonderer Bedeutung sind. In diesem Artikel fassen wir diesen sich abzeichnenden Pathomechanismus zusammen, der die Grundlage für neuartige Therapiestrategien liefern könnte. Wir fokussieren uns auf geänderte Kalziumhomöostase sowie nukleoläre Funktion. Wir diskutieren, wie Tiermodelle mit beeinträchtigter Synthese von ribosomaler RNS im Nukleolus zur Identifizierung neuer zellspezifischer Vulnerabilitätsfaktoren beitragen können, wie komplexe homöostatische Adaptationsmechanismen der SN DA Neuronen eine flexible Anpassung ihrer funktionellen Aktivität an die metabolischen Bedürfnisse ermöglichen können, und wie genau diese Mechanismen SN DA Neurone besonders vulnerabel gegenüber degenerativen Triggerfaktoren und Zelltod im MP machen.
Study of impacts of different evaluation criteria on gamma pass rates in VMAT QA using MatriXX and EPID
Authors: Noufal Manthala Padannayil , Abdullah Kallikuzhiyil Kochunny , Niyas Puzhakkal , Subha Pallimanhayil Abdul Raheem 
Published: December 2017

Abstract
Aim: This study evaluates the impacts of using different evaluation criteria on gamma pass rates in two commercially available QA methods employed for the verification of VMAT plans using different hypothetical planning target volumes (PTVs) and anatomical regions.
Introduction: Volumetric modulated arc therapy (VMAT) is a widely accepted technique to deliver highly conformal treatment in a very efficient manner. As their level of complexity is high in comparison to intensity-modulated radiotherapy (IMRT), the implementation of stringent quality assurance (QA) before treatment delivery is of paramount importance.
Material and Methods: Two sets of VMAT plans were generated using Eclipse planning systems, one with five different complex hypothetical three-dimensional PTVs and one including three anatomical regions. The verification of these plans was performed using a MatriXX ionization chamber array embedded inside a MultiCube phantom and a Varian EPID dosimetric system attached to a Clinac iX. The plans were evaluated based on the 3%/3 mm, 2%/2 mm, and 1%/1 mm global gamma criteria and with three low-dose threshold values (0%, 10%, and 20%).
Results: The gamma pass rates were above 95% in all VMAT plans, when the 3%/3mm gamma criterion was used and no threshold was applied. In both systems, the pass rates decreased as the criteria become stricter. Higher pass rates were observed when no threshold was applied and they tended to decrease for 10% and 20% thresholds.
Conclusion: The results confirm the suitability of the equipments used and the validity of the plans. The study also confirmed that the threshold settings greatly affect the gamma pass rates, especially for lower gamma criteria.
Spatio-temporal trends in the predation of large gulls by peregrine falcons (Falco peregrinus) in an insular breeding population
Authors: Sutton Luke J. , Burrell Ryan A. , Loram Seb 
Published: December 2017

Abstract
Individual diet specialization occurs in many populations of generalist predators, with specific individuals developing specialist strategies in their feeding behaviour. Intraspecific resource partitioning is hypothesised to be common amongst species in higher trophic levels where competition for resources is intense, and a key driver in breeding success and community structure. Though well-studied in other predators, there is sparse data on ecological specialization in raptors, which are important drivers of community and trophic structure. In this study, the breeding season diet of an insular population of peregrine falcons (Falco peregrinus) was determined from indirect analysis of prey remains collected over three years. An unexpected result was the high proportion of large gulls (Laridae), of the genus Larus, in the diet of two breeding pairs of peregrines. Large gulls made up 18.44% by frequency of total prey recorded and 30.81% by biomass. Herring gulls (Larus argentatus) were the most common large gull prey, with immatures most frequent (67.95%) compared to adults (19.23%). Overall, most gulls predated were immatures (80.77%). Frequency of predation varied between breeding pairs and months, but was consistent over the three years. Most gulls were taken in April (37.17%), followed by May (19.23%), with a smaller peak of immature herring gulls taken in August and September. The pattern of regular predation by peregrines on large gulls is a new observation with important implications for understanding individual diet specialization in raptors, and its effect on bird populations and community structure.
Myth and Music - Enhancers of Balance. Between Tradition and Modernity
Authors: Milea Luminița 
Published: December 2017

Abstract
Along with literature, music, through the suggestiveness of the means of expression, manages to render in different compositional forms and genres the specific atmosphere and traits of the mythical universe. The Romanian musical creation has been dynamically asserted in an original manner over time, through the diversification of artistic means and a permanent adaptation of musical language to the aesthetic requirements of each compositional period. Skillfully wielding the processes of modern musical language, composers George Enescu, Aurel Stroe and Cornel Țăranu have given the contemporary public artistic masterpieces which impress by the personal manner of transposing into modernity the transcendent message of the myths of Oedipus and Orestes. The richness of the compositional means employed by the three composers creates bridges between antiquity and modernity, between the imaginary and the real universe.
Euripides – Dramatic Concept, Innovation and Style
Authors: Dulgheriu Ionuț 
Published: December 2017

Abstract
We can say that the Europidian Greek tragedy situated at the outset man to extreme limits, on the border where the divine begins. Any tragedy signifies and stimulates the energy of the hero to surpass himself through an incredible act of courage, to give a new measure of his greatness in the face of obstacles, to the unknown he meets in the world and in the society of his time. The tragedy shows us that in the very fact of human existence there is a challenge, or a paradox, it tells us that sometimes the aspirations of man come into conflict with the forces of the unexplained and destructive, which is beyond and yet very close to us. The poet and philosopher Euripides turns out to be a great humanist, he loves and sympathizes with the people, suggesting that by birth we are all equal.
Answers with strings
Authors: Ciobotaru Anca Doina 
Published: December 2017

Abstract
Carles Cannelas is a puppeteer who has a fine knowledge of the craft, an artist trained in the spirit of the creativity specific to visual arts, and of passion for shape and mechanism. His experience helps him dynamize his sculpture, control his emotions, and manage crises – onstage accidents. His gaze carefully supervises the state of the marionette, his fingers stroll through the strings with firm, yet delicate moves. He loves the character that was born out of his forty-year long experience that could be summed up by these numbers: tours on three continents, in seventeen countries, invitations to participate in two hundred and fifty-one festivals. His journey in the world of theatre has given him a mythical aura; in a way, there is an air of legend surrounding him.
“Bach never lacked violinists, so Peter never lacks puppeteers” – interview with the Bread and Puppet Theater
Authors: Petcu Ioana 
Published: December 2017

Abstract
The American Bread and Puppet Theater, funded and coordinated by Peter Schumann, answered the International Theater Festival for the Young Public’s invitation at its 10th edition. This event was a Prologue, according to the organizers, and took place on the 30th of September. I arrived at theater during their rehearsal for the show presented - “basic byebye cantastoria extravaganza”. It was a great opportunity for me to see the actors patiently adapting their voices to the new stage condition. During a break I talked with three of them – this is how I met young artists Esteli Kitchen, Joe Therrien and Josh Krugman, relaxed, full of energy, and easily immersing themselves into our dialogue, in which I carefully inserted some anarchic ideas and a dash of humor.
A Rare Complication of Patent Ductus Arteriosus Ligation: Inadvertent Ligation of the Left Pulmonary Artery
Authors: Terlemez Semiha , Işık Onur , Şahin Suzan , Akcan Abdullah Barış , Kaynak Türkmen Münevver 
Published: December 2017

Background: The inadvertent ligation of the left pulmonary artery (LPA) is a rarely seen surgical complication that has been presented in the literature in a limited number of cases after patent ductus arteriosus (PDA) ligation surgery. Case Report: A PDA closure operation was performed on our patient, a 28-week-old preterm. In the postoperative follow-up, we identified on echocardiography taken on the same postoperative day that the ductus space was still present. On CT angiography, we determined that not only was the ductus space still continuing, but, in addition, ligation of the LPA had been performed inadvertently. An LPA reconstruction operation was performed on the patient 46 days after the first operation. However, owing to severe tissue damage in LPA, LPA reperfusion did not occur in the postoperative period. Conclusion: Although inadvertent ligation of the left pulmonary artery during PDA ligation surgery is rarely seen in patients who have undergone closure surgery, this complication should be kept in mind in the postoperative follow-up period. Patient findings such as physical examination, lung angiography and postoperative echocardiography should be assessed with this in mind.
Increased Medicaid Payment and Participation by Office-Based Primary Care Pediatricians
Authors: Tang Suk-fong S. , Hudak Mark L. , Cooley Dennis M. , Shenkin Budd N. , Racine Andrew D. 
Published: December 2017

BACKGROUND AND OBJECTIVES:
Whether the Medicaid primary care payment increase of 2013 to 2014 changed physician participation remains unanswered amid conflicting evidence. In this study, we assess national and state-level changes in Medicaid participation by office-based primary care pediatricians before and after the payment increase.

METHODS:
Using bivariate statistical analysis, we compared survey data collected from 2011 to 2012 and 2015 to 2016 by the American Academy of Pediatrics from state-stratified random samples of pediatrician members.

RESULTS:
By 4 of 5 indicators, Medicaid participation increased nationally from 2011 and 2012 to 2015 and 2016 (n = 10 395). Those accepting at least some new patients insured by Medicaid increased 3.0 percentage points (ppts) to 77.4%. Those accepting all new patients insured by Medicaid increased 5.9 ppts to 43.3%, and those accepting these patients at least as often as new privately insured patients increased 5.7 ppts to 55.6%. The average percent of patients insured by Medicaid per provider panel increased 6.0 ppts to 31.3%. Nonparticipants dropped 2.1 ppts to 14.6%. Of the 27 studied states, 16 gained in participation by 1 or more indicators, 11 gained by 2 or more, and 3 gained by all 5.

CONCLUSIONS:
Office-based primary care pediatricians increased their Medicaid participation after the payment increase, in large part by expanding their Medicaid panel percentage. Continued monitoring of physician participation in Medicaid at the national and state levels is vital for guiding policy to optimize timely access to appropriate health care for &gt;37 million children insured by Medicaid.
BROTAÇÃO DE ORA-PRO-NÓBIS EM SUBSTRATO ALTERNATIVO DE CASCA DE ARROZ CARBONIZADA
Authors: Campos Jasmine Alves , Oliveira Neide Judith Faria de , Chamba Juan Sebastian Vera , Colen Fernando , Costa Cândido Alves da , Filho Adair da Silva Santos 
Published: December 2017

Ora-pro-nóbis, conhecido popularmente como “carne de pobre”, é utilizado pelo potencial alimentício e medicinal. A propagação por estacas caulinares constitui a forma de multiplicação usualmente empregada. No entanto, existem poucos estudos sobre o cultivo desse vegetal. Dessa forma, o objetivo com esse trabalho foi avaliar o perfil de brotações estacas caulinares de ora-pro-nóbis em substrato de casca de arroz carbonizada. O estudo foi desenvolvido no Instituto de Ciências Agrárias da Universidade Federal de Minas Gerais (ICA/UFMG). O experimento foi instalado em Delineamento Inteiramente Casualizado (DIC), contendo três tratamentos, estacas do tipo apical, mediana e basal, com respectivamente 30, 60 e 30 repetições. O substrato constitui-se de casca de arroz carbonizada e areia lavada (1:1). Inicialmente, determinou-se o número de gemas e o diâmetro por tipo estaca e porção, avaliado pelo programa SAEG. O número, comprimento e a taxa de sobrevivência foram analisados pelo erro padrão em programa Microsoft Excel® 2013. As estacas do tipo apical apresentaram mais gemas. As primeiras emissões de brotos foram observadas após sete dias do plantio para as estacas medianas e basais. Verificou-se menor taxa de sobrevivência e menor número de brotações em estacas apicais. Quanto ao tipo, as estacas basais destacaram no comprimento nas posições medianas e basais. Estacas basais e medianas apresentaram melhores resultados de número de brotações nas porções. Conclui-se que estacas medianas e basais de ramos de P. aculeata foram mais viáveis e apresentaram mais brotações aos 37 dias. Pesquisas como esta constitui um dado novo, sendo necessários futuros estudos sobre o perfil de enraizamento da espécie.
EDITORIAL
Authors: Leite José Yvan Pereira 
Published: December 2017

Esta é o penúltimo volume de 2017, em que estão publicados 25 artigos com temas variados, caracterizando o compromisso deste periódico com a interdisciplinaridade. No hemisfério sul entramos na quadra do verão, aquela com dias longos e claros. Neste lado do planeta, a ciência e tecnologia, como o verão, precisa de perenidade por longo período para ajudar a alterar a qualidade de vida daqueles que aqui povoam.A solidariedade daqueles que fazem ciência no norte se faz necessária para ampliar a capacidade de resolver problemas e estabelecer a convivência comum com qualidade. O período é para o trabalho árduo - fazer mais com menos e ampliar a capacidade de escolha.Neste contexto, a formação de redes colaborativas nas áreas do open acess e científica são fundamentais para ampliar a qualidade de respostas à sociedade e para a produção científica qualificada. Esta editoria trabalhará para que estas ações se reafirmem.Esta editoria agradece aos autores, pareceristas ad hoc e membros do Conselho Editorial pela confiança e colaboração com este periódico.Enfim, convido-os a acessarem o sumário para conhecer os novos artigos publicados e, quando possível, compartilhem em vossas redes sociais.Em tempo, desejo-os Boas Festas! Natal, 21 dezembro de 2017. José Yvan Pereira Leite
DIVERTICULO DE ESOFAGO MÉDIO: RELATO DE CASO
Authors: Chalela Ayub Nazir Elias , Nunes João Antonio Feriani , Da Costa Josiane Maria , Sivieri Thiago , Morita Shinhiti , De Brito Gilberto Borges 
Published: December 2017

Introdução: Divertículos esofagianos são alterações esofágicas raras e podem ser classificados em proximais, médios ou distais, de acordo com a localização. Podem ser de pulsão ou tração e verdadeiro ou falso. Na dependência do tamanho do divertículo e da concomitância de doença associada, podem causar disfagia, regurgitação, mau hálito, rouquidão ou pneumopatias, podendo ter indicação de ressecção cirúrgica. O diagnóstico é suspeitado pela história clínica e confirmado pelo exame radiológico contrastado e pela endoscopia digestiva alta. Objetivo: Relatar o caso raro de uma paciente com divertículo de esôfago médio. Materiais e Métodos: Revisão do prontuário, registro fotográfico dos métodos diagnósticos e revisão da literatura. Resultados: Paciente feminina, 61 anos, encaminhada ao ambulatório do hospital de base de São José do Rio Preto, com queixa de disfagia progressiva para alimentos sólidos aproximadamente há cinco anos, associado à odinofagia, eructação intensa e perda ponderal nesse período de 10 quilos. A endoscopia digestiva alta, mostrou divertículo no terço médio do esôfago, 25 cm da arcada dentária superior, com óstio de 3-4 cm de diâmetro e 3 cm de profundidade. A tomografia computadorizada de tórax confirmou a presença do divertículo de esôfago em terço médio do esôfago, sem outros achados que justificassem sua presença. A paciente foi submetida à videotoracoscopia com ressecção do divertículo sem intercorrências. Atualmente, a paciente apresenta-se assintomática no acompanhamento clínico. Conclusão: Embora seja considerada uma alteração esofágica rara, os divertículos esofagianos, devem sempre ser considerados como diagnóstico diferencial. Especialmente em casos de disfagia, halitose e enfermidades respiratórias por broncoaspiração. Em casos de pacientes sintomáticos e com dificuldade no tratamento clinico, a melhor opção terapêutica é a cirurgia com a excisão local do divertículo via toracotomia ou toracoscopia.
Powered endoscopic inferior turbinoplasty: clinical study
Authors: Al-Helo Sajad , Falih Hasanain , Jumma Ahmed 
Published: December 2017

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Nasal obstruction is a common complaint in ENT clinics and significantly affect the patient`s quality of life. Inferior turbinate hypertrophy is one of the common causes of nasal obstruction, surgical reduction of inferior turbinate is indicated in refractory cases not responding to conservative measures and the optimal surgical technique is controversial. The aim of the study was to evaluate the clinical outcomes of powered endoscopic inferior turbinoplasty in the management of inferior turbinate hypertrophy. </span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">An interventional study (single group clinical trial) was conducted and powered endoscopic inferior turbinoplasty was performed on 30 patients complaining of chronic nasal obstruction due to inferior turbinate hypertrophy and other causes of nasal obstruction were excluded. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Assessed preoperatively and 1<sup>st</sup> week, 1<sup>st</sup> month and 3<sup>rd</sup> month postoperatively depending on subjective visual analogue scale scores for nasal obstruction, endoscopic grading system and complications. There was significant improvement in nasal obstruction and significant reduction in inferior turbinate size and mild complications that completely absent at the third month following the surgery. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Microdebrider-assisted inferior turbinoplasty as a safe, effective and reliable alternative method for inferior turbinate reduction.</span></p>
Knowledge, attitude and practice about allergic rhinitis in a rural population, Kancheepuram district, Tamil Nadu
Authors: Rajasekaran Valli , Ghosh Puja 
Published: December 2017

<p class="abstract"><strong>Background:</strong> Allergic rhinitis presents a global health problem. The lack of awareness about allergic rhinitis leads to poor adherence to management protocol.</p><p class="abstract"><strong>Methods:</strong> Our cross sectional study in 100 patients with allergic rhinitis was aimed at assessing the knowledge, attitude and practice about the disease. This was done using a questionnaire. Descriptive analysis was made in the three domains and expressed in percentage. </p><p class="abstract"><strong>Results:</strong> The knowledge about the cause and the treatment options was low. Most of the patients were worried about the long term side effects and dependence of the drugs used for treatment of allergic rhinitis. Most patients ignore the symptoms and do not seek medical advice.</p><p dir="ltr"><strong>Conclusions:</strong> Improving the patient’s knowledge and attitude through health education can improve practices among allergic rhinitis patients. </p>
A comparative study in the use of topical mitomycin-C versus nasolacrimal stent in endoscopic dacryocystorhinostomy for chronic dacryocystitis
Authors: Gupta Vikas , Singh Inderdeep , Dwivedi Gunjan , Goyal Sunil , Kumar Manoj , Sood Amit , Upadhyay Madhukar 
Published: December 2017

<p class="abstract"><strong>Background:</strong> Inflammation of the lacrimal sac and duct is a common and unpleasant condition, leading to troublesome epiphora and recurrent dacryocystitis. Surgery is the preferred treatment modality of chronic dacryocystitis which can be performed by external approach or endoscopic nasal approach. Endoscopic dacrycocystorhinostomy (EnDCR) is now a well-established procedure to relieve nasolacrimal duct obstruction, becoming ENT surgeons’ domain. The aim of this study is to assess the efficacy and compare results of intraoperative use of nasolacrimal stent in comparison of mitomycin-C (MMC) in endoscopic dacryocystorhinostomy.</p><p class="abstract"><strong>Methods:</strong> A prospective study of 56 patients with acquired NLDO with epiphora and recurrent dacryocystitis who were evaluated and managed between Oct 2014 and Oct 2016. All patients were offered surgical line of management by endoscopic route. They were randomly assigned into two groups-mitomycin-C group (Group A) and silastic nasolacrimal stenting (Group B). 46 patients who matched inclusion criteria’s were included in the study after formal evaluation by ENT surgeon and Ophthalmologist. 26 patients underwent endoscopic dacryocystorhinostomy with Mitomycin-C application intra – op, 20 patients underwent nasolacrimal silicone stent placement. </p><p class="abstract"><strong>Results:</strong> At 6-month follow-up visit, the management was considered successful if the lacrimal sac irrigation succeeded with relief of symptoms. The success rate in Group A was 92.30%. Group B had 85% success rate. However, no significant (p value=0.37) was noticed between two groups.</p><p><strong>Conclusions:</strong> Despite, no significant difference in outcome between two modalities, there is a trend towards the better outcome with use of mitomycin-C. Mitomycin-C is a safe, effective, and economical adjuvant in endoscopic DCR assisting in improved outcomes of surgery. </p>