bluuebunny/crossref_metadata_2025_split huggingface dataset:
A small, old, and slightly rough mirror: Encountering traumatic experiences in Nanjing Museum of the Site of Lijixiang Comfort Stations
Authors: Sun Hongfang , Liu Guangjian , Yan Jianqiang 
Published: October 2024

AbstractThis paper investigates how traumatic events are curated and narrated in the Nanjing Museum of the Site of Lijixiang Comfort Stations. Drawing on narrative therapy in museology, the paper offers a perspective for understanding and interpreting the narrative practice in public space. It follows the reconstruction of narrative structures through a variety of viewpoints, including spatial narratives, exhibition narratives, public engagement in response to traumatic memories, and the logical and emotional encounters in museums. Visitors' learning of traumatic experiences in the museum shows a kind of indissoluble connection, a type of empathetic mutual understanding, a kind of community engagement that contributed to the recovery, and a kind of responsibility to prevent such traumatic events from happening again.
Computed tomography of the equine caudal spine and pelvis. Pathological findings in 56 clinical cases (2018–2023)
Authors: Ogden Nadine Kristina Elise , Winderickx Katja , Stack John David 
Published: October 2024

AbstractBackgroundComputed tomography (CT) of the axial skeleton is increasing across many equine hospitals. CT of the pelvis and caudal spine in a large group of clinical cases has not been reported previously.ObjectiveTo describe the pathological lesions identified in the caudal spine/pelvis in horses and ponies undergoing CT spine of this region.Study designA retrospective case series.MethodsHorses with CT imaging of the caudal spine/pelvis were included. Horses aged under 6 months and those with CT examinations performed post‐mortem were excluded.ResultsFifty‐six horses met the inclusion criteria. Ages ranged from 8 months to 20 years and bodyweights from 85 to 680 kg (mean 488 kg). Horses presented predominantly for lameness (30/56) and poor performance (18/56). Osseous pathology was identified in 41/56 horses; including osteoarthritis of the sacroiliac joint(s) (n: 28), pathology of the intervertebral disc joint(s) (n: 12), pelvic fractures (n: 9), osteoarthritis of the coxofemoral joint(s) (n: 8), ventral spondylosis (n: 6), acetabular rim fracture (n: 2), dislocation of coxofemoral joint(s) (n: 2), and dorsal dermal sinus of the sacrum (n: 1).Main limitationsThe relationship between CT imaging findings and clinical signs in horses remains unclear. Further work is required to describe the relationship between congenital, developmental, and acquired changes in the caudal spine and pelvis, and clinical signs.ConclusionsCT of the caudal spine and pelvis can be utilised in horses and ponies for diagnosing a range of clinical disorders that may be causing ‘lumbosacroiliac pain’, poor performance, hindlimb lameness, and stiffness. The pathologies we observed were diverse and many patients had multiple lesions.
Identification of Potential Hub Genes in Alopecia Areata
Authors: Liu Runqiu , Liu Longdan , Xu Jiandan , Wen Xiaoting , Jiang Yannan , Qi Qi , Qin Jie , Qin Pingping 
Published: October 2024

ABSTRACTAlopecia areata (AA) is an immune‐mediated chronic alopecia disease, but its specific pathogenesis is unclear. Gene expression data for AA patients (AAs) and healthy controls (HCs) were retrieved from the GEO database, and the differentially expressed genes (DEGs) between AAs and HCs were identified. Then, GO, KEGG and GSEA analysis were performed. A PPI network for the DEGs was then constructed to screen for hub genes, which were validated by three additional datasets. Subsequently, the potential miRNAs interacting with the hub genes were obtained through TarBase and miRNet. The differentially expressed lncRNAs (DElncRs) were obtained for subcellular localisation analysis, and the DElncRs located in the cytoplasm were further screened to identify miRNAs that interact with them. The shared miRNAs interacting with the hub genes and lncRNAs were used to construct a network of mRNA‐miRNA‐lncRNA interactions. Lastly, ROC analysis was performed to evaluate the potential diagnostic value of the hub genes and DElncRs identified. A total of 173 DEGs were obtained, mainly enriched in cytokines, chemokines, hair follicle development and hair cycle related signalling pathways. Through PPI screening and validation based on 3 additional datasets, 24 hub genes were finally yielded. Of them, five hub genes were upregulated and the potential miRNAs that interact with these five hub genes were identified. Additionally, 26 DElncRs were obtained, including 9 upregulated lncRNAs located in the cytoplasm that were predicted to interact with the miRNAs. Finally, an mRNA‐miRNA‐lncRNA regulatory network was constructed using five hub genes, four lncRNAs and their shared five miRNAs. The regulatory relationship between CD8A, mir‐185‐5p and FOXD2‐AS1 might be crucial in AA pathogenesis, with CD8A and FOXD2‐AS1 exhibiting diagnostic potential. CD8A and FOXD2‐AS1 may serve as potential therapeutic targets in AA.
Immigration‐related stress, depression, and positive parenting among undocumented Central American immigrant mothers
Authors: Hernández Dubon Rafael E. , Letiecq Bethany L. , Chaplin Tara , Vesely Colleen K. , Goodman Rachael D. , Marquez Marlene 
Published: October 2024

AbstractObjectiveThe purpose of the current study was to examine whether immigration‐related stress is associated with reduced positive parenting and whether this association is mediated by depressive symptoms in undocumented Central American immigrant mothers.BackgroundIn the context of “illegality,” parents can face myriad stressors related to their immigration status, which may lead to heightened emotions, including depressed mood. These experiences may affect family life, including the ways in which immigrant mothers parent their children.MethodThis study examined survey data generated in 2016–2017 by researchers using a community‐based participatory action research approach in partnership with Central American immigrant mothers residing in the Washington, DC, region. The sample for this study included 117 undocumented Central American immigrant mothers of children aged 3 to 11 years.ResultsControlling for age of child, mother's education, and relationship status, analyses revealed that immigration‐related stress was associated with heightened levels of depressive symptoms for mothers. However, mothers' symptoms of depression were not associated with positive parenting. Additionally, no association between immigration‐related stress and positive parenting was found.ConclusionsFindings suggest that mothers, although affected by immigration‐related stress in terms of their own mood symptoms, may deploy mechanisms such as parental self‐sacrifice to protect their children from anti‐immigrant harms.ImplicationsFindings hold implications for future research, including research approaches, and practice.
RGS10 Deficiency Alleviated Intestinal Mucosal Inflammation Through Suppression of Th1/Th17 Cell Immune Responses in Ulcerative Colitis
Authors: Yang Yonghong , Shao Yiming , Gao Xizhuang , Hu Zongjing , Wang Yan , Ma Cuimei , Jin Guiyuan , Zhu Fengqin , Dong Guanjun , Zhou Guangxi 
Published: October 2024

ABSTRACTRegulator of G‐protein signalling (RGS) 10 plays critical roles in several immune related diseases. However, whether RGS10 is involved in colonic inflammation of ulcerative colitis (UC) is still obscure. This study aimed to investigate the role of RGS10 in UC. In this study, RGS10 expression was examined by quantitative real‐time polymerase chain reaction (qRT‐PCR), western blotting, immunohistochemistry, and immunofluorescent analysis. Single‐cell RNA sequencing of intestinal mucosa was performed to identify key immune cells with differentially expressed RGS10. RGS10 knockout mice were generated and established dextran sulphate sodium (DSS)‐induced colitis. Expression of inflammatory cytokines on mRNA and protein levels was detected by qRT‐PCR, enzyme‐linked immunosorbent assay, and flow cytometry. We found that RGS10 expression was significantly elevated in UC patients, especially in CD4+ T cells, compared with healthy subjects. Intriguingly, RGS10 deficiency markedly alleviated DSS‐induced colitis and decreased the proportion of Th1 and Th17 cells in lamina propria mononuclear cells (LPMCs), peripheral blood (PB), spleens, and mesenteric lymph nodes (mLNs). Mechanistically, RGS10 deficiency blocked the differentiation of Th1 and Th17 cells by inhibiting the phosphorylation of signal transducer and activator of transcription (STAT) 1 and STAT3. The co‐immunoprecipitation analysis further showed that RGS10 could interact with protein tyrosine phosphatase non‐receptor type 2 (PTPN2), and further regulated Th1 and Th17 cells differentiation of CD4+ T cells. In conclusion, RGS10 deficiency alleviated intestinal mucosal inflammation through inhibition of Th1/Th17 cell‐mediated immune responses via interaction with PTPN2 in CD4+ T cells. Therefore, targeting RGS10 may represent a novel therapeutic approach for UC treatment.
Using Implementation Science to Implement Evidence‐Based Practice: A Discursive Paper
Authors: Chays‐Amania Audrey , Schwingrouber Jocelyn , Colson Sébastien 
Published: October 2024

ABSTRACTAimThe purpose of this manuscript is to offer an overview of knowledge regarding Evidence‐Based Practice and implementation science. It addresses the question: What are the EBP implementation models used in nursing settings?DesignDiscursive paper.MethodsThe databases were searched with the following keywords: ‘Nursing Faculty’, ‘Nurse educator’, ‘Academic’, ‘clinic’, ‘Evidence‐based implementation’, ‘evidence‐based practice’, ‘implementation’, ‘implementation science’, ‘undergraduate’, ‘nurse’. The search strategy aims to identify published studies. Eight databases were searched.ResultsThere are specific implementation models for implementing EBP: the IOWA Model, the Stetler Model, the Johns Hopkins Nursing Evidence‐Based Practice Model, the Stevens Star Model, the Promoting Action on Research Implementation in Health Services (PARIHS), the Advancing Research and Clinical practice through close collaboration (ARCC) model. They were analysed according to the Nilsen classification. An evidence‐based implementation project must be structured. First, it is necessary to choose an implementation model, then identify one or more implementation strategies, and finally, plan evaluation for implementation outcome. The use of implementation science ensures successful implementation or at least highlights barriers that need adjustment. Effective utilisation of implementation science facilitates the transfer of obtained results to similar contexts.ConclusionImplementation science complements the EBP process perfectly and ensures the proper implementation of evidence.Implication for the ProfessionEBP mentors now have the entire structure of implementation science to succeed in implementing evidence‐based data in both academic and clinical settings.ImpactThe discursive paper addresses the difficulties of implementing evidence in academic or clinical settings. Implementation science is the bridge between evidence and practice. Nurses now have everything they need to implement evidence‐based practice successfully.No Patient or Public ContributionThere was no patient or public involvement in the design or writing of this discursive article.
Treatment Modalities of Uncomplicated Crown Fracture in Anterior Maxillary Permanent Teeth: A Systematic Review
Authors: Paulina  , Dhawan Pankaj , Jain Neha 
Published: October 2024

ABSTRACTAimSeveral treatment modalities have been used to restore crown fractures in case of uncomplicated crown fractures. Although many treatment modalities have been reported, there is no consensus on which one has the best results in terms of success and durability. This systematic review of treatment modalities in uncomplicated crown fractures aims to provide the most common and successful treatment modality for each patient's unique needs, balancing conservation, aesthetics, and long‐term durability.Materials and MethodsThree electronic databases (PubMed, Scopus, and Google Scholar) were searched for articles regarding treatment modalities in uncomplicated crown fractures in anterior maxillary teeth.ResultsFollowing the application of the inclusion and exclusion criteria, 10 case reports, four case series, and two retrospective studies were selected for the review. These studies reported on fragment reattachment, direct composite resin, and veneers for the management of uncomplicated crown fractures. Fragment reattachment was the most preferred treatment modality, with milk, water, or sterile saline used as storage mediums. Direct composite restoration was preferred for missing or bad‐shaped fragments or longevity. Veneers were given for aesthetic consideration and fracture resistance when the crown structure was majorly affected by the fracture. Fragment reattachment was favored in 63% of the articles included in the review followed by direct composite restoration in 26% of the articles. Venners were used in about 11% of the articles. Composites depicted a higher survival rate and a better outcome than fragment reattachment. Follow‐up periods ranged from 1 week to 4 years, and all articles successfully re‐established function and aesthetics, except for one tooth that required root canal treatment.ConclusionFragment reattachment, direct composite restoration, and veneers are successful treatment modalities in uncomplicated crown fractures of anterior teeth. The choice of treatment depends on various factors like availability of fragments, age, and financial condition of the patient.Trial RegistrationPROSPERO Registration ID: CRD42020153091
Reliability and Educational Suitability of TikTok Videos as a Source of Information on Sleep and Awake Bruxism: A Cross‐Sectional Analysis
Authors: Cannatà Davide , Galdi Marzio , Russo Alessio , Scelza Carmine , Michelotti Ambrosina , Martina Stefano 
Published: October 2024

ABSTRACTBackgroundTikTok contains many videos about bruxism that may help raise the level of awareness on the topic. However, the quality of these videos' information represents the greatest concern.ObjectiveThe present cross‐sectional analysis aimed to systematically assess the reliability and educational suitability of TikTok videos as a source of information on bruxism.MethodsTikTok was searched for relevant videos uploaded until 6 March 2024, using the hashtags #bruxism, #grindingteeth and #jawclenching. Independent pre‐calibrated operators conducted video inclusion and data collection, noting videos' characteristics, source, popularity, content, reliability (assessed through the DISCERN scoring system) and educational value (assessed through the Global Quality Score [GQS]). The Kruskal–Wallis test was adopted to compare videos from different sources. Videos with low and high educational value were compared using the Mann–Whitney U‐test. Tests were considered significant when the p‐value was < 0.05.ResultsA total of 105 bruxism videos were analysed. Most videos covered bruxism management and clinical features, and more than 60% were uploaded by healthcare professionals. According to the DISCERN and GQS scoring, the videos' reliability and educational value were judged to be very poor and low, respectively, but on average they were higher for videos uploaded by healthcare professionals compared to those uploaded by laypeople. When comparing videos with high educational value to those with low educational value, differences were found in popularity, content and reliability.ConclusionThe present results suggest the need for greater control of information disseminated on social media to fulfil its potential role in educating laypeople about bruxism.
“We Want to be There to Support … Do We Have the Capacity to Do That?” Current Priorities and Challenges in School Social Work
Authors: Murphy Jennifer , Borge Katherine A. , Harrell Danielle R. , Javna Alex , Craft Kaija 
Published: October 2024

ABSTRACTBACKGROUNDWhile adolescent mental health needs have continued to rise, schools have become a central location for adolescents seeking support for mental health needs, and approximately 96% of public schools in the United States report providing some form of mental health care to students. This study aims to explore school social workers' current challenges and priorities in their roles.METHODSQualitative focus groups with current school social workers in Virginia (N = 16) were conducted for this study. Participants worked in middle and high schools for a minimum of 3 years across the state. Braun and Clarke's steps for thematic analysis were used to guide coding and themes.RESULTSThe current study found 3 primary themes: (1) role confusion due to vast scope of responsibilities within their schools; (2) a disconnect between desired roles and assigned roles and responsibilities; and (3) lack of formal model of service provision.IMPLICATIONS FOR SCHOOL HEALTH POLICY, PRACTICE, AND EQUITYFocus should be placed on the integration of current models of school social work practice to ensure the effective utilization of their services.CONCLUSIONSThe study reveals important information regarding the current and future state of school social work practice.
Risk factors for enteral nutrition feeding intolerance in stroke patients: A scoping review
Authors: Solomon Owusu Mensah , Gu Yujia , Wei Yehong 
Published: October 2024

AbstractBackgroundFeeding intolerance is a common issue in stroke patients who are receiving enteral nutrition, and it has a substantial effect on their recovery and rehabilitation. Understanding the various factors of feeding intolerance in this patient population is vital for improving care and outcomes.AimThis review aims to map the existing literature on enteral nutrition in stroke patients, identifying key themes, gaps and areas for future research.Study designThis review was conducted as a scoping review following the PRISMA Extension for Scoping Reviews (PRISMA‐ScR) checklist to ensure comprehensive coverage and methodological rigour. We conducted a scoping review by searching databases such as PubMed, CINAHL, Scopus, Web of Science, CNKI and WangFang from 1 January 2000 to 31 January 2024. We aimed to locate research about issues with enteral nutrition feeding in stroke patients. We collected data on the patient's characteristics, medical status, therapies, feeding protocols and nursing care. A total of 25 articles met the inclusion criteria and were included in the review.ResultsTwenty‐two influencing factors were identified and categorized into patient factors (5), disease factors (8), treatment factors (2), feeding management factors (5) and nursing factors (2). Notably, age, intra‐abdominal pressure, serum albumin levels, APACHE‐II scores and central venous pressure (CVP) were among the most commonly reported.ConclusionsThis scoping introduction uniquely focuses on stroke patients receiving enteral nutrition, explaining specific influencing factors for feeding intolerance.Relevance to Clinical PracticeHealth care professionals must identify and manage risk factors for enteral nutrition feeding intolerance. Ongoing professional development and specialized training on the significance of enteral feeding in stroke rehabilitation can improve patient care and outcomes.
Instantaneous growth: a compact measure of efficient carbon and nitrogen allocation in leaves and roots of C3 and C4 plants
Authors: Bellasio Chandra 
Published: October 2024

AbstractElucidating plant functions and identifying crop productivity bottlenecks requires the accurate quantification of their performance. This task has been attained through photosynthetic models. However, their traditional focus on the leaf's capacity to uptake CO2 is becoming increasingly restrictive. Advanced bioengineering of C3 plants has made it possible to increase rates of CO2 assimilation by packing photosynthetic structures more densely within leaves. The operation of mechanisms that concentrate CO2 inside leaves can boost rates of assimilation while requiring a lower investment in carboxylating enzymes. Therefore, whether in the context of spontaneous plants or modern manipulation, considering trade‐offs in resource utilization efficiency emerges as a critical necessity. I've developed a concise and versatile analytical model that simulates concurrent leaf and root growth by balancing instantaneous fluxes of carbon and nitrogen. Carbon is made available by leaf photosynthesis, encompassing all types of biochemistries, while nitrogen is either taken up by roots or remobilized after senescence. The allocation of leaf nitrogen between light or carbon reactions was determined using a fitting algorithm: growth maximisation was the only reliable fitting goal. Both the leaf nitrogen pool and the root‐to‐leaf ratio responded realistically to various environmental drivers (CO2 concentration, light intensity, soil nitrogen), replicating trends typically observed in plants. Furthermore, modifying the strength of CO2 concentrating mechanisms proved sufficient to alter the root‐to‐leaf ratio between C3 and C4 types. This direct and mechanistic one‐to‐one link convincingly demonstrates, for the first time, the functional dependence of a morphological trait on a single biochemical property.
Comprehensive transcriptome profiling and transcription factor identification in early/late leaf senescence grafts in potato
Authors: He Ming , Li Boshu , Hui Zhiming , Liu Jiangang , Bian Chunsong , Li Guangcun , Jin Liping , Xu Jianfei 
Published: October 2024

AbstractPotato (Solanum tuberosum L.) is recognized globally as the most significant non‐cereal staple crop. Leaf senescence, which significantly impacts tuber yield, serves as a critical indicator of potato maturity. Despite its importance, the molecular mechanisms regulating this process remain largely unknown. In a previous study, we grafted the early‐maturing variety ‘Zhongshu 5’ (Z5) onto the late‐maturing variety ‘Zhongshu 18’ (Z18), and demonstrated that the rootstock's leaves displayed physiological characteristics suggestive of early senescence. Here, we analyzed the transcriptome data of the Z5 and Z18 grafts to conduct weighted gene co‐expression network and gene expression clustering analysis. Differentially expressed genes in cluster 9, as well as the floralwhite module, exhibited markedly elevated expression levels during the onset of leaf senescence. These genes were found to be enriched in several senescence related processes, such as chloroplast organization, electron transport chain, and chlorophyll metabolic process. Furthermore, we constructed transcription factor correlation networks and hub gene co‐expression networks. By monitoring the expression patterns of these genes throughout the whole growth period, we identified two candidate genes, StWRKY70 and StNAP, which may play pivotal roles in leaf senescence. This study contributes valuable genetic resources for further investigations into the regulatory mechanism governing potato leaf senescence, with implications for genetic improvements, particularly in terms of maturity and yield.