bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reporting community involvement in autism research: Findings from the journal Autism
Authors: Tan Diana Weiting , Crane Laura , Haar Tori , Heyworth Melanie , Poulsen Rebecca , Pellicano Elizabeth 
Published: September 2024

Participatory methods are having sweeping effects on research across the globe. To facilitate transparency around these methods, Autism introduced mandatory reporting of community involvement in January 2021. Here, we sought to determine the impact of this policy. To do so, we – a team of Autistic and non-autistic researchers – searched for articles published in Autism in 2019, 2 years before policy implementation, and in 2022, 1 year after. We read 283 eligible articles and double coded each article for general information and details of community involvement. We found a fivefold increase (10.3% pre-implementation vs 54.5% post-implementation) in the reporting of community involvement. Most articles reported involving community members distally, in consulting roles, with researchers retaining full decision-making power. Furthermore, most community involvement was reported in more applied than basic research. A significant minority of papers (17%), however, could not be coded, owing to insufficient or vague information. While this increase in the reporting of community involvement is encouraging, more efforts need to be directed towards (1) improving the transparency in the reporting of community involvement and (2) increasing the frequency with which community members, especially Autistic people, share decision-making power equally with researchers – or even assume control of the research process. Lay abstract There has been a growing push for the Autistic and autism communities to be more actively involved in autism research. From January 2021, the journal Autism made it a rule for authors to report whether they involved community members in their work; and if they did, how they had done so. In this study, we wanted to see how this new rule has changed things. Our team of Autistic and non-autistic researchers read all 283 articles published in Autism in 2019, about 2 years before the rule was in place, and in 2022, about 1 year after. We recorded what each article was about and how the community was involved. We found there was an increase in how often articles talked about community involvement – from about 10% before the rule to over 50% after. Most of these studies, however, only involved community members giving advice, with the researchers making most decisions about the research. This was especially true for applied research (like wellbeing) rather than basic science (like causes of autism). Also, some of these articles were unclear or did not give enough information for us to understand how the community was involved. This tells us that while it is promising that more community involvement is reported, researchers need to describe this involvement more clearly. It is also important for community members to have a bigger say in research by sharing power with the researchers or even leading the research themselves.
Relations among degree of bilingualism and bilateral information processing in children and adults
Authors: Sierra Francisco J. , Weimer Amy A. , Lin Yu-Cheng , Jou Jerwen , Castillo Nayda , Garcia Cedar , Suarez Michelle , Garcia Flor I. , Aleman Gabriela , Ortiz Edson , Romero Francheli 
Published: September 2024

Aims and objectives: The primary goal of this study was to examine whether degree of bilingualism related to dichotic listening accuracy, a measure of bilateral processing, after controlling for age and income. Methodology: Participants included 59 children ages 6–11 years ( M = 7.86, SD = 1.81) and 61 adults (18–83 years) ( M = 34.02, SD = 15.70). Participants completed demographic surveys, vocabulary assessments in English and Spanish, and a dichotic listening test. Data and analysis: Multiple linear regressions examined whether the degree of bilingualism predicted bilateral processing. Findings: Degree of bilingualism predicted bilateral processing in the whole sample of children and adults. Originality: This study is one of the first to examine bilingualism and bilateral processing while including both children and adults. It also importantly controlled for a possible cognate facilitatory effect and participant income differences and measured bilingualism on a continuum. Significance: Results highlight the importance of including bilingual groups of different ages when researching bilingualism and laterality.
The thermal responses of composite box girder bridges with corrugated steel webs under solar radiation
Authors: Cai Chenzhi , Xu Ming , He Xuhui , Zou Yunfeng , Huang Shiji 
Published: September 2024

Owing to the direct exposure to complex atmospheric environments, the temperature field of composite box girder bridge with corrugated steel webs (CBGB-CSW) is likely non-uniformly distributed. Whereas, the current researches regarding the thermal responses of CBGB-CSW are insufficient, and the thermal responses of CBGB-CSW under solar radiation are still unknown. Therefore, this paper conducted a long-term temperature experiment on a scaled model to explore the temperature distribution characteristics in CBGB-CSW. Meanwhile, a three-dimensional thermal–mechanical coupling Finite Element (FE) model is established to simulate the temperature field in the experiment girder. The accuracy and effectiveness of the developed FE model has been verified by the measured temperature data. Therewith, the thermal responses (i.e., stress and displacement) of a full-scale continuous CBGB-CSW with a span of 150 m are numerically investigated. The results indicate that the maximum stresses always occur at the midspan section (with a depth of 5 m) of the continuous CBGB-CSW, and considerable concentrations of stress are observed in the steel-concrete junction. The maximum longitudinal tensile and compressive normal stresses within 0.4 m of the upper junction can reach 5.55 MPa and −8.46 MPa respectively, and those of the lower junction can reach 6.96 MPa and −7.05 MPa respectively. Besides, owing to the impacts of vertical and horizontal temperature gradients, significant displacements of the whole bridge can also be observed. The maximum vertical displacement (5.33 mm) of the CBGB-CSW is estimated at the top plate in the midspan, while the maximum horizontal displacement (0.74 mm) is estimated at the trough of the southern corrugated steel web in the midspan. Notably, the outcomes of this paper can provide some useful references for engineers and scholars to understand the thermal responses of the CBGB-CSW.
Comparison of Different Head Tilt Angles in Tomotherapy and Volumetric Modulated Arc Therapy for Hippocampal-Avoidance Whole-Brain Radiotherapy
Authors: Li Yang , Yuan Cuiyun , Chen Dongjie , Xu Sisi , Jiang Wei , Huang Jiaxin , Ye Shanshan , Zhang Yin , Liang Jun , Liu Chenbin 
Published: September 2024

Purpose Hippocampal-avoidance whole-brain radiotherapy (HA-WBRT) planning can present challenges. This study examines the influence of head tilt angles on the dosimetric characteristics of target and organs at risk (OARs), aiming to identify the optimal tilt angle that yields optimal dosimetric outcomes using tomotherapy (TOMO). Methods Eight patients diagnosed with brain metastases underwent CT scans at five tilt angles: [0°, 10°), [10°, 20°), [20°, 30°), [30°, 40°), and [40°, 45°]. Treatment plans were generated using TOMO and volumetric modulated arc therapy (VMAT). Dosimetric parameters including conformity index (CI), homogeneity index (HI), D2cc, D98%, and Dmean of PTV, as well as Dmax, and Dmean of OARs were analyzed. Furthermore, a comparison was made between the dosimetric parameters of TOMO and VMAT plans. Finally, delivery efficiency of TOMO plans were assessed. Results For the PTV, [40°, 45°] tilt angle demonstrated significantly better conformity, homogeneity, lower D2cc, and lower Dmean for the PTV. Regarding the OARs, the [40°, 45°] head tilt angle demonstrated significantly lower Dmax and Dmean in hippocampus, eyes, optic chiasm, and optic nerves. The [40°, 45°] tilt angle also showed significantly lower Dmax for brainstem and cochleas, as well as a lower Dmean for lens. In the [40°,45°] tilt angle for HA-WBRT, TOMO showed superior performance over VMAT for the PTV. TOMO achieved lower Dmax for brainstem, cochleas, optic nerves, and optic chiasm, as well as a lower Dmean for hippocampus. Furthermore, a significant correlation was found between delivery time and the PTV projection length in the sagittal plane. Conclusion The TOMO plan utilizing a tilt angle range of [40°, 45°] demonstrated superior PTV conformity and uniformity, along with enhanced OARs sparing. Furthermore, it exhibited a dosimetric advantage over VMAT for PTV and most OARs at the same angle range.
Barriers to stroke treatment: The price of long-distance from thrombectomy centers
Authors: Søvik Olav , Øygarden Halvor , Tveiten Arnstein , Kurz Martin Wilhelm , Kurz Kathinka Dæhli , Stokkeland Pål Johan , Hetland Hanne Brit , Ersdal Hege Langli , Hyldmo Per Kristian 
Published: September 2024

Background Endovascular thrombectomy, the preferred treatment for acute large-vessel occlusion stroke, is highly time-dependent. Many patients live far from thrombectomy centers due to large geographical variations in stroke services. This study aimed to explore the consequences of long transport distance on the proportion of thrombectomy-eligible patients who underwent thrombectomy, the clinical outcomes with or without thrombectomy, the timelines for patients transported, and the diagnostic accuracy of large-vessel occlusion in primary stroke centers. Methods We conducted a retrospective observational study in a county with only primary stroke centers, ∼ 300 km from the nearest thrombectomy center. All stroke patients admitted over a year were retrieved from the Norwegian Stroke Registry. A neuroradiologist identified all computed tomography images with large-vessel occlusions. A panel determined whether these patients had a corresponding clinical indication for thrombectomy. Results A total of 50% of the eligible patients did not receive thrombectomy. These patients had a significantly higher risk of severe disability or death compared to the patients who underwent thrombectomy. The median time from computed tomography imaging at the primary stroke center to arrival at the thrombectomy center was over 3 hours. Additionally, 30% of the large-vessel occlusions were initially undiagnosed, and half of these patients had a corresponding clinical indication for thrombectomy. Conclusions In a county with a long transport distance to a thrombectomy center, a high proportion of eligible patients did not undergo thrombectomy, negatively impacting clinical outcomes. The transport time was considerable. A high rate of large-vessel occlusions was initially not diagnosed.
Understanding the association between menstrual health and hygiene attitudes and personal agency among very young adolescents in Sao Paulo, Brazil: A cross-sectional study
Authors: Borges Ana Luiza Vilela , Chofakian Christiane Borges do Nascimento , Cabral Cristiane da Silva , Ramaiya Astha 
Published: September 2024

Background: Although menstruation is a monthly biological phenomenon, it is shrouded in stigma and shame which directly impacts health, education, gender equality, decent work, and economic growth. However, there is scarce evidence on how personal agency, an individual’s ability to access resources, may act as a protective factor to adequate menstrual health and hygiene practices. Therefore, we assess the association between attitudes toward menstruation and personal agency among very young adolescent girls. Methods: We use cross-sectional data from the Global Early Adolescent Study in São Paulo, Brazil, among 10- to 14-year-old girls who have experienced menarche ( n = 325) and completed a home-based self-administered questionnaire in 2021. “Attitudes toward menstruation” was created based on five indicators on a Likert scale, with a higher score indicating more positive attitudes. The main covariate was personal agency, comprised of three scales and modeled as three continuous variables: voice, decision-making power, and freedom of movement. Data were analyzed using multivariable linear regression. Results: Attitudes toward menstruation mean score was 12.5 (range 5–19). Older adolescents (12–14 years-old) had higher mean scores (more positive) than younger adolescents (10–11 years-old) on attitudes toward menstruation, whereas no other sociodemographic or menstrual health indicator (knowledge or access to products) were associated with attitudes toward menstruation. In the multiple regression model, older age and higher freedom of movement remained positively associated with attitudes toward menstruation (βadjust = 0.5; 95%CI 0.1 to 0.8). Conclusion: Positive attitudes toward menstruation are associated with higher freedom of movement among very young Brazilian adolescent girls. The promotion of personal agency should be recognized as key strategies to accelerate young girls’ positive approaches to their own menstruation and, consequently, well-being.
Are characteristics associated with strong Black womanhood linked to depression in older Black women?
Authors: Erving Christy L , Frazier Cleothia , Davidson-Turner KJ 
Published: September 2024

Background: Older Black women experience structural and intersectional disadvantages at the intersection of age, race, and gender. Their disadvantaged social statuses can translate into serious psychological health consequences. One concept that may aid in understanding psychosocial determinants of older Black women’s depression risk is the “Strong Black Woman,” which suggests that Black women have supernatural strength amidst experiencing adversity and are expected to “be strong” for others by providing self-sacrificial aid without complaint. Objectives: Drawing inspiration from the “Strong Black Woman” concept, the current study examined whether three psychosocial factors (i.e., mastery, anger suppression, and relational demands (from spouse, children, relatives, and friends)) were associated with depressive symptoms, clinically significant depressive symptoms, and lifetime professionally diagnosed depression among older Black women (i.e., ages 50 years and older). Design: This was a cross-sectional study. Data were drawn from the 2010 to 2012 waves of the Health and Retirement Study ( N = 1,217). Methods: For past-week depressive symptoms, ordinary least squares regression analyses were conducted, and beta coefficients were reported. For clinically significant depressive symptoms (i.e., reporting three or more depressive symptoms in the past week) and lifetime professionally diagnosed depression, binary logistic regression analyses were performed, and odds ratios were reported. Results: Higher levels of mastery were associated with lower risk for depressive symptoms and depression. Anger suppression was associated with higher risk for depressive symptoms and depression. Demands from children and one’s spouse were associated with higher depressive symptoms while demands from family were associated with risk for lifetime depression diagnosis. Not having a spouse was associated with heightened risk of depressive symptoms and depression. Interestingly, demands from friends were not associated with depressive symptoms nor diagnosed depression. Conclusion: Study findings revealed important nuances in the determinants of depression among older Black women which, in turn, has implications for research and mental health care provision in this population.
The prevalence of asthma and its predictor among patients presenting in Ethiopian public hospitals: systematic review and meta-analysis, 2024
Authors: Adal Ousman , Mamo Sosina Tamire , Belay Alamirew Eneyew , Tsehay Yeshimebet Tamir , Netsere Henok Biresaw , Mulatu Sileshi , Mekonnen Gebrehiwot Berie , Messelu Mengistu Abebe , Abebe Gebremeskel Kibret , Wondie Wubet Tazeb , Tafere Chernet , Belayneh Asnake Gashaw 
Published: September 2024

Background: Asthma is a leading cause of emergency hospital visits and a significant factor in lost productive hours. The lack of a synthesized body of knowledge on bronchial asthma has notable public health implications. Objective: This systematic review and meta-analysis aim to investigate the prevalence of asthma and its predictors among patients presenting in Ethiopian public hospitals. Design: Duplicate studies were removed using EndNote version X9. The Newcastle–Ottawa Scale guided the quality assessment, and data extraction followed the Joanna Briggs Institute format. Data source and methods: The authors used advanced search methods, including databases such as PubMed, Scopus, Embase, Africa Index Medicus, Science Direct, HINARI, Google Scholar, and manual searches. Data presentation adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Publication bias was assessed using Egger’s regression test and a funnel plot. Sensitivity analysis was also conducted. Results: The search yielded 352 original articles, with 22 meeting the criteria for inclusion. Using the random-effects DerSimonian-Laird model, the prevalence of bronchial asthma was found to be 9.02% (95% CI: 7.50, 10.53). Several factors were associated with the prevalence of bronchial asthma, including the spring season (AOR 3.7; 95% CI: 2.11, 6.49), childhood age (AOR 4.2; 95% CI: 1.84, 9.55), and urban residence (AOR 1.7; 95% CI: 1.29, 2.31). Other significant factors include family history of asthma (AOR 2.89; 95% CI: 2.22, 3.75), insecticide exposure (AOR 3.3; 95% CI: 2.23, 4.91), and the presence of household insects like cockroaches (AOR 3.33; 95% CI: 2.15, 5.15). Smoking (AOR 3.64; 95% CI: 2.66, 4.98), obstructive sleep apnea (AOR 4.29; 95% CI: 2.37, 7.76), and recurrent upper respiratory tract infections (AOR 4.31; 95% CI: 2.24, 8.32) were also significant. Conclusion: The pooled prevalence of bronchial asthma is notably high in Ethiopia. Key predictors include childhood age, spring season, urban living, family history of asthma, exposure to insecticides, presence of cockroaches, smoking, obstructive sleep apnea, and recurrent upper respiratory infections. Targeted interventions are crucial and should focus on lifestyle improvements, allergen identification, cockroach control, smoking cessation, reducing insecticide exposure, and promoting a safe environment. Trial registration: This review’s protocol was pre-registered with the International Prospective Register of Systematic Reviews (PROSPERO registration number CRD42023491222).
Weekend endoscopic retrograde cholangiopancreatography has similar outcomes as weekday procedures—a propensity score match analysis of the Hungarian ERCP Registry
Authors: Tajti Máté , Pécsi Dániel , Mátrai Péter , Gódi Szilárd , Hegyi Péter , Szentesi Andrea , Altorjay István , Bakucz Tamás , Orbán-Szilágyi Ákos , Szepes Zoltán , Patai Árpád , Gyökeres Tibor , Fejes Roland , Dubravcsik Zsolt , Vincze Áron , Czakó László 
Published: September 2024

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is essential for the minimally invasive management of biliary and pancreatic disorders. Under certain indications, performing ERCP without delay during the weekend can be important for improving outcomes. Objectives: To compare the outcomes of ERCP performed on weekends and holidays with those of regular weekday ERCPs. Design: Propensity score match analysis of the data from the Hungarian ERCP Registry. Methods: A total of 116 ERCPs were performed during weekends or holidays, and 3144 during weekday working hours. The analyses were performed on 1:2 propensity-matched groups (116 weekend and 232 weekday cases). Results: Weekend ERCPs were mostly performed for acute cholangitis and acute biliary pancreatitis (70% of cases), whereas in the weekday group, only 32% of cases were performed for these indications. No significant difference was found between weekday and weekend ERCPs in terms of the rates of successful (91.38% vs 93.1%, p = 0.565) and difficult (33.62% vs 36.64%, p = 0.511) biliary cannulations. We found no significant differences in the number of adverse events (bleeding, post-ERCP pancreatitis, and 30-day mortality) in ERCPs performed during weekends or weekdays. Moreover, no significant differences in the aforementioned outcomes were detected between the propensity-matched groups. Conclusion: In this propensity-matched study, no significant differences were found in the outcomes of weekend and weekday ERCPs.
Mechanism of Anchang Decoction in Treatment of Anti-Inflammatory Effect Based on Network Pharmacology, Molecular Docking and Experimental Verification
Authors: Tian Wei , Zhou Weiqian , Huang Shi , Qin Qiuyun , Fang Weilong , Zhou Lijie , Yang Xihong 
Published: September 2024

Context A prescription medication called Anchang Decoction (ACD) has anti-inflammatory properties. Objective To evaluate the mechanism of ACD against inflammation. Materials and methods The “pharmacodynamic constituents - potential targets” and “protein interaction networks” were mapped using Cytoscape software and the STRING database, respectively. The degree of binding between important pharmacodynamic components of ACD and possible targets was then examined using molecular docking analysis using Autodock Vina and PyMOL software, and GO and KEGG pathway enrichment analysis using the David database and the Weishengxin online tool. These findings were eventually confirmed in vitro. Results After the intersection of the two, 539 inflammatory targets and 217 related targets, 34 main active components, and 42 potential anti-inflammatory targets were obtained. These include AKT1, MAPK14, SRC, EGFR, GSK3B, MMP9, MMP2, PTGS2, SYK, ESR1, and MMP2 and GO enrichment results. These three key targets are chosen as downstream validation targets for experimental verification. Furthermore, the colonic tissue and mucosa of ACD group were undamaged in comparison to the model group, and there was no sign of inflammatory cell infiltration. According to CCK-8 data, treatment with 20% ACD drug-containing serum resulted in a significant increase in RAW264.7 cell viability (P < 0.05) when compared to the normal serum group; Serum of ACD-containing medication may considerably lower the NO content of macrophage inflammation and prevent the production of inflammatory markers like TNF-α and IL-6 (P < 0.05); The expression levels of AKT1, MAPK14, and SRC proteins were considerably reduced by ACD in RAW264.7 macrophage inflammation, according to Western Blot data (P < 0.05). Discussion and conclusions ACD exerts anti-inflammatory effects through multi-component interaction with the target, and the mechanism may involve the inhibition of the release of inflammatory cytokines by AKT, MAPK and non-receptor tyrosine kinase signaling pathways. Here, the molecular mechanism of ACD against inflammation was partially clarified and experimentally validated, offering theoretical evidence for more effective clinical application.