bluuebunny/crossref_metadata_2025_split huggingface dataset:
Travel burden and bypassing closest site for surgical cancer treatment for urban and rural oncology patients
Authors: Onega Tracy , Ramkumar Niveditta , Brooks Gabriel A. , Loehrer Andrew P. , Kapadia Nirav S. , O'Malley A. James , Fraze Taressa K. , Smith Rebecca E. , Wang Qianfei , Wong Sandra L. , Tosteson Anna N. A. 
Published: October 2024

AbstractPurposeWe examined the relationship between travel burden for surgical cancer care and rurality, geographic bypass of the nearest surgical facility, cancer type, and mortality outcomes.MethodsUsing Medicare claims and enrollment data (2016–2018) from beneficiaries with cancer of the colon, rectum, lung, or pancreas, we measured travel times to: the nearest surgical facility and facility used. For those who bypassed the nearest, we examined travel time and rurality in relation to surgical rates. Using multivariable regression modeling, we estimated associations of bypass with 90‐day postoperative‐ and one‐year mortality; rurality was examined as an effect modifier.FindingsAmong 211,025 beneficiaries with cancer, 25.5% resided in non‐metropolitan areas. About 66% of metropolitan/micropolitan, and 78% of small town/rural patients bypassed their closest facility. Increasing rurality was significantly associated with increased likelihood of bypass (Referent = metropolitan, OR; 95%CI: micropolitan 1.10; 1.04–1.16, small town/rural 2.08; 1.96–2.20. Bypassing the nearest facility was associated with decreased likelihood of both 90‐day postoperative mortality (OR = 0.79; 95%CI 0.74–0.85) and 1‐year mortality (OR = 0.81; 95%CI 0.77–0.86). The greatest decrement in 1‐year mortality was for pancreatic cancer across all rural‐urban categories (OR; 95%CI: metropolitan 0.63; 0.53–0.76; micropolitan 0.53; 0.29–0.97); small town/rural 0.46; 0.25–0.86).ConclusionsMost Medicare beneficiaries with lung, colon, rectal, or pancreatic cancer bypassed the closest facility providing surgical cancer care, especially rural patients. Bypassing was associated with a lower likelihood of 90‐day postoperative, and 1‐year mortality. Understanding determinants of bypassing, particularly among rural patients, may reveal potential mechanisms to improve cancer outcomes and reduce rural cancer disparities.
Role ofPNPLA3in Hepatic Stellate Cells and Hepatic Cellular Crosstalk
Authors: Castanho Martins Maria , Dixon Emmanuel Dauda , Lupo Giulia , Claudel Thierry , Trauner Michael , Rombouts Krista 
Published: October 2024

ABSTRACTAimsSince its discovery, the patatin‐like phospholipase domain containing 3 (PNPLA3) (rs738409 C>G p.I148M) variant has been studied extensively to unravel its molecular function. Although several studies proved a causal relationship between the PNPLA3 I148M variant and MASLD development and particularly fibrosis, the pathological mechanisms promoting this phenotype have not yet been fully clarified.MethodsWe summarise the latest data regarding the PNPLA3 I148M variant in hepatic stellate cells (HSCs) activation and macrophage biology or the path to inflammation‐induced fibrosis.ResultsElegant but contradictory studies have ascribed PNPLA3 a hydrolase or an acyltransferase function. The PNPLA3 I148M results in hepatic lipid accumulation, which predisposes the hepatocyte to lipotoxicity and lipo‐apoptosis, producing DAMPs, cytokines and chemokines leading to recruitment and activation of macrophages and HSCs, propagating fibrosis. Recent studies showed that the PNPLA3 I148M variant alters HSCs biology via attenuation of PPARγ, AP‐1, LXRα and TGFβ activity and signalling.ConclusionsThe advent of refined techniques in isolating HSCs has made PNPLA3's direct role in HSCs for liver fibrosis development more apparent. However, many other mechanisms still need detailed investigations.
Posterior Circulation Ischemic Stroke From Atlantoaxial Instability and Lateral Dislocation due to Os Odontoideum: Case Report and Review of Literature
Authors: Wang Xianghe , Li Yao , Shao Minghao , Liang Jingjuan , Tang Weijun , Lin Jixian , Ma Xiaosheng , Wang Hongli , Han Xiang 
Published: October 2024

ABSTRACTBackgroundStrokes in young individuals often stem from unusual causes. Posterior circulation ischemic stroke caused by vertebral artery insufficiency due to atlantoaxial instability or dislocation is rare. We present a case of posterior circulation ischemic stroke due to an unstable os odontoideum and review the current literature. The clinical features and imaging manifestations are described to promote awareness of etiology, early diagnosis, and assessment.Case PresentationA 24‐year‐old male presented with recurrent right‐sided limb numbness and weakness and cerebellar ataxia due to posterior circulation ischemic stroke. The work‐up revealed thrombosis reformation in the tortuous left vertebral artery. It is noteworthy that the patient developed compression and chronic damage of the vertebral artery secondary to atlantoaxial instability and lateral dislocation due to an os odontoideum. He underwent antiplatelet and anticoagulant therapy, cervical traction, and posterior atlantoaxial screw fixation and fusion with iliac crest autograft. The postoperative course was uneventful. At 6‐month follow‐up, the patient had a solid fusion mass and rigid stability of the atlantoaxial joint without neurologic deficits or ischemic sequelae.ConclusionsFor unexplained posterior circulation ischemic stroke, it is important to consider unstable os odontoideum as a potential etiology, especially in pediatric and young adult male patients. Atlantoaxial instability and dislocation with os odontoideum, especially when occurring laterally, may cause insufficiency of the vertebral artery and subsequent posterior circulation ischemic strokes. The significance of lateral atlantoaxial dislocation in the genesis of vertebral artery injury and the necessity for specific positional imaging are emphasized.
Experts – Part I: What They Are and How to Identify Them
Authors: Croce Michel , Baghramian Maria 
Published: October 2024

AbstractThis paper investigates the topic of expertise in cognitive domains from a socio‐epistemological perspective. In particular, two central questions in the epistemology of expertise are discussed: what an expert is according to extant theories on the market; and how ordinary people can identify an expert in domains in which they have no competence of their own.
THE NOTION OF SEQUENTIALITY IN LANGUAGE: AN INVESTIGATION IN COGNITIVE SEMANTICS
Authors: Hamawand Zeki 
Published: October 2024

AbstractThis research aims to clarify the concept of sequentiality in language: the case in which a number of things occur one after the other, as seen in phrases like a queue of customers, a strand of programs and a fleet of cars. Utilizing Langacker's theory of Cognitive Semantics, the study seeks to substantiate two claims. The first is that the meaning of a linguistic expression is understood in terms of the domain in which it is embedded. The second is that the meaning of a linguistic expression is the outcome of the specific construal imposed on its content. The paper proposes that the choice of a sequential phrase is influenced by how the speaker perceives and describe a situation. The study intends to demonstrate that each sequential phrase carries a unique meaning that sets it apart from others. When two or more sequential phrases modify a noun, they indicate semantic contrast, with each phrase offering a different perspective. The findings show that sequential phrases have distinct functions and are distinguishable in their usage through examples provided.
SlMYB72 interacts with SlTAGL1 to regulate the cuticle formation in tomato fruit
Authors: Wu Mengbo , Zhou Yuanyi , Ma Haifeng , Xu Xin , Liu Mingchun , Deng Wei 
Published: October 2024

SUMMARYThe cuticle is the first physical barrier covering the surface of tomatoes and plays an important role in multiple stress responses. But the molecular regulatory networks of cuticle formation are not fully understood. In this study, we found that SlMYB72 can interact with SlTAGL1 to regulate the formation of fruit cuticle in tomato. Downregulating the expression of SlMYB72 inhibits the formation of fruit cuticle, resulting in a reduced fruit cuticle thickness, accelerated postharvest water loss, and increased susceptibility to Botrytis cinerea. RNA sequencing analysis showed that downregulation of the SlMYB72 gene decreased the expression levels of genes related to fatty acid and cuticle metabolism. SlMYB72 regulates the cuticle formation by directly binding to the promoter of long‐chain acyl‐coA synthetases (SlLACS1) and medium‐chain alkane hydroxylase (SlMAH1). Moreover, SlMYB72 interacts with SlTAGL1, which can enhance the transcriptional activation of SlMYB72 on the SlMAH1 promoter. Overall, our study expands our understanding of the regulation of cuticle formation by SlMYB72 and provides new insights into fruit shelf life extension via manipulation of cuticle content.
Third eyelid cartilage eversion in an adult mare
Authors: D'Agostino Albert L. , Giuliano Elizabeth A. , Kuroki Keiichi , Martin Lynn M. 
Published: October 2024

AbstractPurposeTo describe the first report of third eyelid cartilage eversion in an adult American Quarter Horse mare.Case PresentationA 22‐year‐old American Quarter Horse mare presented to the University of Missouri Veterinary Health Center Equine Hospital for a 2‐week history of a third eyelid cartilage abnormality of the left eye with no known recent trauma. Complete ophthalmic examination revealed third eyelid cartilage eversion of the left nictitans. The abnormal scrolled cartilage was surgically excised using a handheld cautery unit and submitted for histopathologic evaluation.ResultsHistopathologic findings displayed normal third eyelid cartilage, without evidence of neoplasia or inflammation. Mucosal hyperplasia and increased vascularity of the submucosa were observed. The horse healed well after electrocautery excision and normal third eyelid conformation was restored.ConclusionTo the authors' knowledge, this is the first report of an acquired, presumed spontaneous, third eyelid cartilage eversion in a horse.
Pilot feasibility randomised controlled trial of cognitive–behavioural therapy for functional cognitive disorder after concussion
Authors: Rioux Mathilde , Mamman Rinni , Byworth Miles T , Panenka William J , Howard Andrew K , Perez David L , Schmidt Julia , Courchesne Caitlin , LeMoult Joelle , Heran Manraj KS , Silverberg Noah D 
Published: October 2024

BackgroundFunctional cognitive disorder (FCD) may be common after a concussion, and no evidence-based treatment options are available. The current study evaluated the feasibility of a novel cognitive–behavioural therapy (CBT) protocol tailored to FCD after concussion.MethodsParticipants were randomised to CBT (n=11) or the current standard of care, cognitive rehabilitation (n=13). Both interventions consisted of eleven 50 min manualised videoconference sessions. CBT involved cognitive reappraisal and exposure-based strategies. Cognitive rehabilitation involved traditional memory compensation strategy training. Prespecified feasibility criteria were set for recruitment, perceived credibility, patient adherence, therapist protocol compliance and retention. The primary efficacy outcome was the Multifactorial Memory Questionnaire-Satisfaction (MMQ-S). The first five CBT completers completed a semistructured interview about their experience with the intervention.ResultsMost feasibility benchmarks were met, as 86% of invited patients consented, 96% of participants rated their intervention as credible, participants attended 96% of sessions, therapists covered all essential content in 94% of sessions and 100% of participants completed the post-treatment evaluation. Both groups improved on the MMQ-S. Post-treatment MMQ-S scores were similar between groups (Cohen’s d=−0.05 (95% CI [−0.86, 0.75])). Two themes resulted from the qualitative data analysis, which highlighted aspects of the CBT interventions that participants valued.ImplicationsThis pilot trial supports the feasibility of CBT tailored to FCD after concussion and suggests that patients with FCD may benefit from either CBT or standard cognitive rehabilitation. A larger trial is needed to evaluate the efficacy of these interventions for FCD after concussion and potentially FCD in other clinical contexts.Trial registration numberNCT05581810.
Impact of Artificial Intelligence–Based Technology on Nurse Management: A Systematic Review
Authors: Gonzalez-Garcia Alberto , Pérez-González Silvia , Benavides Carmen , Pinto-Carral Arrate , Quiroga-Sánchez Enedina , Marqués-Sánchez Pilar 
Published: October 2024

Aim: To describe the use of artificial intelligence (AI) by nurse managers to enhance management, leadership, and healthcare outcomes.Background: AI represents a significant transformation in healthcare management by enhancing decision‐making, communication, and resource optimization. However, the integration and strategic application of AI in nursing management are underexplored, particularly regarding its impact on leadership roles and healthcare delivery.Methods: Methodological guidelines described by PRISMA were followed, and quality was assessed using the Joanna Briggs Institute (JBI) methodology. The databases searched included the Web of Science, Scopus, CINAHLi, and PubMed. The review included quantitative, qualitative, and mixed‐method studies published between January 2015 and April 2024.Results: Fourteen studies were selected for the review. The key findings indicate that AI technologies facilitate better resource management, risk assessment, and decision‐making. AI also supports nurse managers in leading changes, enhancing communication, and optimizing administrative tasks.Conclusion: AI has been progressively integrated into nursing management, demonstrating significant benefits in operational efficiency, decision support, and leadership enhancement. However, challenges, such as resistance to technological change and ethical complexities, need to be addressed.Implications for Nursing Management: Specific training programs for nurse managers are essential to optimize the integration of AI. Such programs should focus on the management of AI applications and data analyses. In addition, creating interdisciplinary groups involving nurse managers, AI developers, and nursing staff is crucial for tailoring AI solutions to meet the unique needs of healthcare settings.
Factors Associated With Uptake of Breast Cancer Screening Among Catholic Nuns in Lake Zone, Tanzania
Authors: Marandu Gotfrida , Laisser Rose , Malale Kija , Rambau Peter 
Published: October 2024

Background: Breast cancer is the most common cancer among women worldwide. Breast cancer screening programs are widely promoted because of their effectiveness in the early detection of cancer. However, a significant proportion of eligible Catholic nuns in the Lake Zone of Tanzania remain underscreened. This study is aimed at investigating the factors associated with breast cancer screening uptake among Catholic nuns in Lake Zone, Tanzania.Methods: This was a cross‐sectional study design among 385 catholic nuns. Simple random sampling was deployed to enrolled catholic nuns, the ODK collect v2023.2.4 was electronically used to collect data. Binary logistic regression was used to assess the factors associated with the uptake of breast cancer screening. Statistical analysis was performed using STATA 18.0, with a significance level set at a p value less than 0.05.Result: The prevalence uptake of breast cancer screening (i.e., breast self‐examination, clinical examination, or mammography examination) was 64% (n = 247, 95% CI, 59.3%–68.9%). A total of 57.4% had inadequate knowledge on the uptake of breast cancer screening (n = 221, 95% CI, 52.4%–62.4%). Also, the study found that 61.3% (95% CI, 56.4%–66.2%) of Catholic Nuns have negative attitudes towards the uptake of self‐breast examination among Catholic nuns. The findings revealed that 55.6% (n = 133, 95% CI, 50.6%–60.6%) and 52.7% (n = 52.7%, 95% CI, 47.7%–57.7%) of Catholic nuns negatively accept breast cancer screening and self‐breast examination, respectively. Nuns aged above 60 years were less likely to not perform BCS with a COR of 0.62 (95% CI, 0.39–0.97). Also, Catholic nuns who are in the nonhealth field are more likely to not perform BCS with a COR of 1.71 (95%, 1.07–2.74). Likewise, Catholic nuns who had negative acceptability of the Self‐breast examination were more likely to not perform BCS with an AOR of 1.65 (95% CI, 1.07–2.55).Conclusion: A study found a low uptake of breast cancer screening among Catholic nuns. This highlights the need for breast health intervention programs within religious congregations to address misconceptions and promote early detection.
Covering Gaza
Authors: Harb Zahera 
Published: October 2024

Abstract
When journalists witness the same horrors inflicted on their people by a powerful military, anxieties around the concepts of objectivity, impartiality, balance and neutrality in journalism become paramount. Amid military campaigns described as war crimes, journalistic values, including truthfulness, accuracy and accountability, gain even greater significance. Journalists are vital in bearing witness to these atrocities, uncovering the truth and holding perpetrators accountable, even in the most perilous conditions. In the context of the war on Gaza, as well as the conflicts in southern Lebanon and Ukraine, traditional objectivity, I suggest here, is unattainable. The only semblance of truth emerges within a positioned or contextual framework. This perspective is evident in the coverage by Gazan journalists during the Israeli military atrocities, reflecting the broader challenges of war journalism. This article argues that journalists faced with the stark realities of war, they inevitably adopt a positioned objectivity, recognizing the impossibility of detachment or neutrality when confronted with the horrors of conflict. Many Western journalists and audiences have long viewed objectivity and impartiality as absolute ideals unaffected by context. However, this mindset should be challenged, as context should indeed shape our understanding of these concepts.
Avicenna on the Faculties of the Soul: A Critical Analysis with an Examination of Faḫr al-Dīn al-Rāzī’s Criticisms
Authors: Amirkhani Sajad , Varzdar Keramat 
Published: October 2024

Abstract
This article examines Avicenna’s responses to three questions regarding the soul: (1) Why does the soul require faculties? (2) Why are the soul’s faculties multiple? (3) What is the criterion for their multiplicity? Avicenna uses the rule of one and the soul’s simplicity to explain these questions, introducing multiple faculties to resolve the paradox of the soul performing various actions. He argues that the diversity of faculties is due to the generic difference between actions. Faḫr al-Dīn al-Rāzī raises four objections to Avicenna’s explanation. This paper also scrutinizes al-Rāzī’s objections to understand Avicenna’s theory better.
Sustainable integration of insects into European food chains
Authors: Veldkamp T. , Meijer N. , Alleweldt F. , Deruytter D. , Van Der Borght M. , Vandeweyer D. , Gasco L. , Roos N. , Smetana S. , Fernandes A. , van der Fels-Klerx H.J. 
Published: October 2024

Abstract
The European Commission’s Circular Economy Action Plan (CEAP) is a cornerstone of the European Green Deal, aiming for transition towards a more sustainable and circular economy by addressing waste reduction and promoting recycling of low-opportunity cost biomass. The EU Horizon 2020 project SUStainable INsect CHAIN (SUSINCHAIN) aligns with these goals, focusing on the efficient utilisation of insects in the food chain to strengthen sustainable supply chains, enhance consumer acceptance, and create market opportunities. The project, targeted at Technology Readiness Level 6, addresses barriers through comprehensive research, technology demonstrations, and stakeholder collaboration. Results contribute to scaling up the insect sector by overcoming supply and demand challenges, fostering trust, and developing best practices. The opinions generated encompass market opportunities, insect rearing, processing, safety, and sustainability, providing guidelines for stakeholders, public authorities, policymakers, and academia to collectively drive the growth and acceptance of the European insect sector.
The Martijn Trilogy Manuscripts: An Open Dataset for Analyzing Scribal Variation
Authors: Moors Sofie , Kestemont Mike , Sleiderink Remco 
Published: October 2024

Abstract
The authors present a dataset containing transcriptions of manuscripts of the Middle Dutch strophic poem Martijn Trilogy by the Flemish poet Jacob van Maerlant. Of his very large oeuvre, Maerlant’s Strophic Poems had the longest tradition: originally written in the thirteenth century, copyists and printers continued to disseminate them until about 1500. These ten shorter poems on social, religious, and ethical issues stand out for their unusual and complex stanza form. The Martijn Trilogy was his most successful strophic poem: 17 text witnesses are extant, and the trilogy was imitated and even translated into French and Latin. This dataset contains hyperdiplomatic transcriptions of all witnesses, amounting to a total of 15,814 verses or 79,337 tokens. This open-access dataset abides by the fair principles, is licensed under a cc-by-sa license, and is made available in multiple, complementary file formats. Since these transcriptions are strictly diplomatic, this corpus offers valuable possibilities for research on scribal attributions (scribal profiling), abbreviations, stemmatology, textual stability and more.
Can Data Empower Indigenous People? Unveiling an Innovative Dataset for Quantitative Analysis, Replication Modeling, and Economic Development
Authors: Onsay Emmanuel , Rabajante Jomar 
Published: October 2024

Abstract
Indigenous peoples are among the most vulnerable, ignored, and marginalized groups in society. Poverty is the oldest social problem and difficult to counter. The Indigenous people with which the authors live and work, the Agta Tabangnon, suffer from poverty and multidimensional socioeconomic deprivations. Indigenous peoples’ studies are qualitative, while poverty studies are typically generic, exposed to large sampling errors, and intended for nationwide decisions. Therefore, measuring poverty for specific tribes through complete enumeration with multifaceted disaggregation is critical for economic development. There is no comprehensive census specifically designed for Indigenous peoples to encompass the multidimensional aspects of their way of life. Nonetheless, the authors are resourceful in generating useful datasets from their partners. The locale is situated in the poorest district of the poorest province in the poorest region of Luzon, Philippines. The datasets contain multidimensional poverty indicators that are readily usable, along with complementary analytics to visualize the data. They may serve to measure poverty in Indigenous communities across different regions and countries. By utilizing this data, further empirical analysis, regressions, machine learning, and econometric modeling can be conducted. It can be freely utilized to target policies that address the multifaceted poverty and promote economic development within tribal communities.