bluuebunny/crossref_metadata_2025_split huggingface dataset:
Description of the Late Holocene South‐east Saline Everglades, Florida palustrine depositional environment with comparisons to other Holocene environments
Authors: Meeder John F. 
Published: October 2024

AbstractA transgressive palustrine depositional model is described for the South‐east Saline Everglades, Florida. The origin, development and termination of freshwater carbonate mud (marl) deposition along the very low gradient Late Pleistocene carbonate ramp are responses to changing rates of rising sea level during the Late Holocene. The onset of the Late Holocene is defined by a decrease in the rate of sea‐level rise from between 2 and 3 to <1 mm year−1. Freshwater marl deposition began with this decrease ca 3165 ± 187 year BP, in a shallow (<0.3 m deep), ephemeral wetland that developed landward of a fringing mangrove forest and is maintained by seasonal Everglades water delivery. Sedimentation kept pace with sea‐level rise forming a 1.2 m thick wedge shaped, landward thinning deposit. The rate of global sea‐level rise began to accelerate ca 1900, the Anthropocene Marine Transgression, and presently the regional rate is 9.4 mm year−1. Saltwater encroachment rates >80 m year−1 are driven by sea‐level rise. Saltwater encroachment resulted in retreat and transformation of coastal communities and their biogenic facies, resulting in a decrease in freshwater wetlands and marl production. Inundation ponding, mangrove overstep and the beginning of submergence are the responses to the accelerating rate of sea‐level rise, however, small scale topographic and tidal ingress differences create considerable variability between Biscayne Bay and Florida Bay coastal basins. The freshwater marl producing habitat will probably be lost within 55 years, and submergence within the next century at the present rate of sea‐level rise. The unique South‐east Saline Everglades depositional environment is compared to other Holocene palustrine depositional environments.
Human–Wildlife Conflict in Bardia—Banke Complex: Patterns of Human Fatalities and Injuries Caused by Large Mammals
Authors: Paudel Umesh , KC Rabin Bahadur , Kadariya Rabin , Karki Ajay , Shrestha Bishnu Prasad , Shah Shyam Kumar , Subedi Naresh , Thapa Shyam Kumar 
Published: October 2024

ABSTRACTHuman fatalities and injury from wildlife attacks often result in a negative attitude toward conservation. This research was undertaken to investigate the patterns and conflict‐causing factors of human killing and injury by large mammals, especially by Asian elephant (Elephas maximus), common leopard (Panthera pardus), and Bengal tiger (Panthera tigris tigris) in the Bardia—Banke Complex of western Nepal. We collected human death and injury records caused by wildlife in the Bardia—Banke Complex between 2019 and 2023, based on relief applications submitted by the victim's family. Additionally, camera trap monitoring was conducted following incidents of human–tiger and human–leopard conflicts. A total of 76 incidents involving human casualties and injuries were considered for analysis. Incidents of livestock depredation, crop raiding, and property damage were excluded from the analysis. Most of the attacks on humans were caused by tigers (75%), followed by elephants (16%) and leopards (9%). Almost all incidents occurred in daytime (97%). The highest number of conflicts were recorded in 2021, with 20 incidents. Most of the cases (84%) occurred within 1 km of forest edge. Khata corridor and the western side of the Bardia National Park, i.e., Karnali River corridor, were identified as high‐conflict areas. The primary causes of the conflict manifested in cattle grazing (28%), grass cutting (28%), firewood collection (11%), fishing (8%), vegetable collection (5%), sand collection (4%), during rescuing friends (3%), grazing captive elephants (3%), highway rides (3%), sleeping in Chaupadi Goth (3%), walking nearby forest areas (3%), playing nearby forest areas (1%), while feeding pig (1%), and working in agricultural lands (1%). To promote human–wildlife coexistence, community‐based patrols (33%), habitat restoration (26%), electric fencing (26%), and insurance (7%) were identified as the preferred strategies. Therefore, we recommend that stakeholders and concerned bodies increase awareness among local community about the use of forest resources, wildlife behavior, and human–wildlife conflict mitigation strategies.
Cardiovascular outcomes with exenatide in type 2 diabetes according to ejection fraction: The EXSCEL trial
Authors: Neves João Sérgio , Leite Ana Rita , Mentz Robert J. , Holman Rury R. , Zannad Faiez , Butler Javed , Packer Milton , Ferreira João Pedro 
Published: October 2024

AimsGlucagon‐like peptide‐1 receptor agonists reduce major adverse cardiovascular events (MACE) and cardiovascular mortality in people with type 2 diabetes (T2D). However, previous studies suggest the effects on heart failure outcomes vary according to left ventricular ejection fraction (LVEF). We aimed to evaluate the effects of exenatide on cardiovascular events according to LVEF in people with T2D.Methods and resultsPost‐hoc analysis of the Exenatide Study of Cardiovascular Event Lowering (EXSCEL) trial evaluating the effects of once‐weekly exenatide (EQW) versus placebo on cardiovascular outcomes according to baseline LVEF (<40% or ≥40%). Outcomes were also evaluated according to New York Heart Association (NYHA) class and obesity. The main outcome was hospitalization for heart failure (HHF). A treatment‐by‐LVEF interaction was used. In EXSCEL (n = 14 752), 4749 participants had LVEF available at baseline; 455 (10%) with LVEF <40%, 4294 (90%) with LVEF ≥40%. LVEF modified the EQW effect on hHF: hazard ratio (HR) = 1.52 (95% confidence interval [CI] = 0.95–2.43) in participants with LVEF < 40% and HR = 0.74 (95% CI = 0.55–1.01) in those with LVEF ≥ 40% (p‐interaction = 0.012). No significant treatment‐by‐LVEF interactions (p‐interaction >0.10) were observed for MACE, cardiovascular death or all‐cause mortality. The risk of HHF was also modified by baseline NYHA class (HR 0.91, 95% CI 0.65–1.27 for NYHA class I/II; HR 1.84, 95% CI 0.95–3.59 for NYHA class III/IV; p‐interaction = 0.062), mostly driven by the LVEF <40% subgroup. Obesity did not modify the effects of EQW on HHF.ConclusionsThe EQW effect on HHF was influenced by LVEF, with a potentially decreased risk in participants with LVEF ≥40% and increased risk in those with LVEF <40%. The risk of HHF was particularly high in participants with LVEF <40% and NYHA class III/IV. LVEF did not modify the effect of EQW on atherosclerotic outcomes.
Acceptorless Dehydrogenation of Glycerol Catalysed by Ir(III) Complexes with Carbohydrate‐Functionalised Ligands: A Sweet Pathway to Produce Hydrogen and Lactic Acid
Authors: Boccalon Elisa , Menendez Rodriguez Gabriel , Trotta Caterina , Ruffo Francesco , Zuccaccia Cristiano , Macchioni Alceo 
Published: October 2024

AbstractGlycerol, a by‐product of biodiesel production, has gained prominence as a precious platform chemical. To enhance the economic viability of the biodiesel production process and address the surplus of glycerol production, it is essential to transform it into value‐added products. In this context, homogeneous catalysis offers a promising avenue for glycerol valorisation. In this study, we introduce a family of iridium complexes bearing picolineamidate ligands with glucose‐functionalised substituents as novel homogeneous catalysts for glycerol to hydrogen and lactic acid conversion. These complexes exhibit high activity (conversion up to 53.3 %) and 99 % selectivity after 24 hours of reaction (TOFMAX=159 h−1, TON24h=2498). Notably, the reaction occurs under ambient air and at milder temperature conditions (120 °C) compared to other catalysts. These efforts in glycerol valorisation contribute to reducing biodiesel production costs, increasing the competitiveness of biofuels against petroleum‐based liquid fuels, giving rise to H2, through a global process with negative carbon dioxide emission, and lactic acid utilizable, among other, as a monomer for the synthesis of biodegradable plastics.
Using contribution analysis to assess evaluation capacity outcomes in community organizations
Authors: Bourgeois Isabelle , Buetti David 
Published: October 2024

AbstractCommunity organizations face challenges in addressing the needs of their members and beneficiaries, particularly during times of crisis. More than ever, evidence‐informed programming and decision‐making are essential to help organizations “do more with less”; however, community organizations seldom have the individual and organizational evaluation capacity required to conduct and use evaluations to inform decision‐making. This article provides an overview of the evaluation of the LaboEval evaluation capacity building (ECB) intervention, a 5‐year program implemented in 16 organizations. LaboEval brings together direct and indirect individual and organizational ECB activities to enhance evaluation capacity. Contribution analysis (CA) was used as the evaluation approach in this study, assessing the intervention's activities, outputs, outcomes, and assumptions. Data sources include interviews, document reviews, surveys, administrative data, and a literature review. This evaluation contributes to the field by applying CA to a multiyear, multi‐organizational ECB intervention. The findings inform evaluation capacity builders and evaluators interested in CA, showcasing a unique approach to evaluating complex interventions across multiple organizations.
Influence of Brown Rice, Pea, and Soy Proteins on the Physicochemical Properties and Sensory Acceptance of Dairy‐Free Frozen Dessert
Authors: Hasan Towhid , Thoo Yin Yin , Siow Lee Fong 
Published: October 2024

ABSTRACTFat and protein derived from milk are prime ingredients in a frozen dessert such as ice cream conferring multiple desirable functionalities. However, this frozen dairy dessert is not suitable for individuals having lactose intolerance, cow milk allergy, or vegans. Hence, the study aimed to formulate dairy‐free frozen desserts using plant oils and plant proteins and compare their physicochemical characteristics and sensory acceptance against an ice cream containing milk fat and milk protein. Results indicated that the types of protein significantly influenced the physicochemical properties and sensory acceptance of the frozen dessert samples. Frozen desserts containing brown rice, pea, and soy protein showed greater resistance to melting (0.29, 0.12, and 0.19%/min vs. 1.95%/min), but they scored lower in sensory quality than ice cream made with milk protein; although they remained at an acceptable level. When compared among the plant proteins, the physicochemical characteristics of frozen desserts containing brown rice, pea, and soy protein varied because of the differences in the respective protein composition. Frozen dessert with brown rice protein showed higher overrun (47.50% vs. 40.78% and 37.8%), lower hardness (20.02 N vs. 22.24 and 26.37 N), and higher melting rate (0.29%/min vs. 0.19 and 0.12%/min) than frozen desserts containing soy and pea protein. Additionally, the brown rice protein frozen dessert received lower sensory acceptance than soy and pea protein frozen desserts. In summary, brown rice, pea, and soy proteins showed potential to be used as viable alternatives to milk protein for dairy‐free frozen dessert applications.
Analysis of European Association of Urology Guidelines 2023 and its adherence to GRADE methodology
Authors: Dahm Philipp , Holten Mathew , Ratanawong John P. , Lauwagie Andrew , Gonzalez‐Padilla Daniel A. 
Published: October 2024

AbstractIntroductionThe European Association of Urology (EAU) has reported the use of a modified Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach for developing guideline recommendations since 2018; however, the full adoption of GRADE remains a work in progress.MethodsTwo members of the research team identified and independently abstracted all individual recommendations and summary of evidence statements available from all EAU guidelines published in 2023. We evaluated the current adherence to established criteria for appropriate GRADE use, the proportion of strong and weak recommendations, the underlying strength of evidence, and criteria for appropriate use of GRADE.ResultsWe included a total of 20 guideline documents with a total number of 1985 recommendations. The median number of strong recommendations was 46 (interquartile range: 32–87), representing 62.6% of all recommendations. The surgical thromboprophylaxis guideline had the lowest percentage of strong recommendations (18.2%; 30/165), and the neuro‐urology guideline had the highest percentage (95.5%; 42/44). EAU guidelines provided 2580 summaries of evidence statements, of which 1608 reported a level of evidence. The reported levels of evidence were I, II, III and IV/V at 31.8%, 28.5%, 32.4% and 7.3%, respectively. Of the six criteria for the appropriate use of GRADE, criterion 6, which reports the framing of recommendations as strong or weak, was met consistently; all other criteria were met only by a single guideline on thromboprophylaxis.ConclusionsThe EAU guidelines adoption of GRADE has been largely limited to the framing of recommendations as strong or weak. In all but one guideline, published guidelines did not meet any of the other criteria for appropriate GRADE use. Increased efforts to fully adopt GRADE, similar to its implementation in the thromboprophylaxis guideline in future editions, may enhance trust and uptake of EAU guidelines, thereby assisting policymakers and improving patient care.
Allogeneic transplantation for adult T‐cell leukemia/lymphoma in adolescent and young adults and young patients: A nationwide retrospective study by the ATL working group of the Japan society for transplantation and cellular therapy
Authors: Itonaga Hidehiro , Fukushima Takuya , Kato Koji , Nakano Nobuaki , Kato Takeharu , Tanaka Takashi , Eto Tetsuya , Mori Yasuo , Kawakita Toshiro , Uchida Naoyuki , Fujioka Machiko , Nakamae Hirohisa , Ogata Masao , Morishima Satoko , Fukuda Takahiro , Kanda Yoshinobu , Atsuta Yoshiko , Fuji Shigeo , Yoshimitsu Makoto 
Published: October 2024

AbstractAllogeneic hematopoietic stem cell transplantation (allo‐HSCT) provides durable remission for patients with adult T‐cell leukemia/lymphoma (ATL); however, few studies have focused on post‐transplant outcomes in ATL patients ≤49 years. To clarify prognostic factors in ATL among patients <40 years (adolescents and young adult [AYA]; n = 73) and 40–49 years (Young; n = 330), we conducted a nationwide retrospective study. Estimated 3‐year overall survival (OS) rates were 61.8% and 43.1% in AYA and Young patients, respectively (p = 0.005). In the multivariate analysis, Young patients showed worse OS (Hazard ratio (HR) [95% confidential interval] 1.62 [1.10–2.39], p = 0.015), chronic graft‐versus‐host disease (GVHD)‐free and relapse‐free survival (CRFS) (HR 1.54 [1.10–2.14], p = 0.011), and GVHD‐free and relapse‐free survival (GRFS) (HR 1.40 [1.04–1.88], p = 0.026) than AYA patients. No significant differences were observed in OS, CRFS, or GRFS between the myeloablative conditioning (MAC) and reduced‐intensity conditioning (RIC) regimens; however, non‐relapse mortality was significantly lower in patients with the RIC regimen than those with the MAC regimen (HR 0.46 [0.24–0.86], p = 0.015). In summary, OS was worse in Young patients than in AYA patients in the allo‐HSCT setting for ATL. Furthermore, the RIC regimen has potential as an alternative treatment option for ATL patients ≤49 years.
The influence of hope and optimism on trajectories of COVID‐19 stress, health anxiety, and wellbeing during the COVID‐19 pandemic
Authors: Long Laura J. , Viana Andres G. , Zvolensky Michael J. , Lu Qian , Gallagher Matthew W. 
Published: October 2024

AbstractIntroductionThe COVID‐19 pandemic posed a threat to public health and psychological functioning, with early studies documenting higher rates of psychopathology within the United States and globally. Hope and optimism promote adjustment and are associated with positive physical and mental health outcomes. Thus, individual differences in hope and optimism may also foster resilience during a global health crisis.AimsThe current study examined how hope and optimism influenced longitudinal health‐focused distress and wellbeing during the pandemic.MethodsData were collected from 788 American adults across three periods during Spring‐Summer 2020 using MTurk. Latent growth curve modeling examined whether hope and optimism predicted COVID stress, health anxiety, and wellbeing trajectories.ResultsCOVID stress and health anxiety decreased after the onset of the pandemic, whereas wellbeing was stable. Individually, hope and optimism predicted lower initial COVID stress and health anxiety, along with greater initial wellbeing. When examining the combined influence of hope and optimism, optimism was more strongly related to health‐focused distress, though both were strong predictors of wellbeing.ConclusionsThese findings indicate that Americans were resilient and positive expectancies, particularly optimism, predicted better initial adjustment to the early phases of the pandemic. Thus, positive expectancies appear to be protective during a global health crisis.
A comprehensive investigation of oxygen/graphite carbon nitride smart Nano coatings for sustainable maintenance and sacrificial anode protection of mild steel
Authors: Morsy Ashraf , Toderas Monica , El‐marghany Adel , Rana Dipak , Abdelaty Mahmoud , Shokry Fathy , Mohamed M.E. , Abd‐El‐Khalek D.E. , Elkaliuoby Mai.I. , Blall Elsayed G 
Published: October 2024

AbstractBACKGROUNDThis study enhancing the corrosion resistance of mild steel (MS) by incorporating photo‐catalyst‐doped graphitic carbon nitride (g‐C₃N₄) nano‐sheets containing silver (Ag) and oxygen (O₂) into a solar light‐active photoelectrochemical anticorrosion paint with polyester (PE). The objective is to provide sacrificial anode protection through visible light activation.RESULTSThe developed paint forms a uniform film on the MS surface, effectively providing anodic protection under visible light. Characterization techniques, including energy‐dispersive X‐ray spectroscopy (EDX), transmission electron microscopy (TEM), Fourier‐transform infrared spectroscopy (FTIR), and UV–Vis spectroscopy, confirm the molecular structure of the nano‐sheets. Corrosion resistance, assessed through weight loss measurements and open circuit potential (OCP) tests, shows significant improvement with the addition of Ag/g‐C₃N₄ and Ag‐O₂/g‐C₃N₄ nano‐sheets at an optimized concentration of 15 mg. The protection efficiency is ranked as follows: O₂‐g/C₃N₄ > O‐g/C₃N₄ > Ag‐O₂/g‐C₃N₄ > Ag‐g/C₃N₄ > g‐C₃N₄. After 28 days of immersion in seawater, MS coated with O₂/g‐C₃N₄ exhibited the least weight loss, with an inhibition efficiency of up to 99%. Electrochemical impedance spectroscopy (EIS) further demonstrated enhanced coating resistance for the O₂/g‐C₃N₄ coating (Rct = 3.76 kΩ.cm2, Rcoat = 1.69 kΩ.cm2) compared to pure PE (Rct = 0.005 kΩ.cm2, Rcoat = 0.096 kΩ.cm2).CONCLUSIONThe synthesized O₂/g‐C₃N₄ and Ag‐O₂/g‐C₃N₄ nano‐sheets exhibit high surface areas and enhanced water dispersibility, which contribute to significant corrosion protection of MS. The electrochemical performance, including weight loss and OCP measurements, highlights the potential of these nano‐sheet photo‐catalysts in advancing corrosion resistance technologies, with broad implications for materials science and engineering applications. © 2024 Society of Chemical Industry (SCI).
Psychosocial impact on individuals who received negative test results from predictive testing for Huntington's disease: An exploratory qualitative study
Authors: Osawa Harumo , Matsukawa Manami , Yoshida Akiko , Torishima Masako , Murakami Hiromi , Haruyama Sayoko , Wada Takahito , Kosugi Shinji 
Published: October 2024

AbstractHuntington's disease (HD) is a neurodegenerative disease with autosomal dominant inheritance, and no radical cure for HD has been established. Qualitative studies are necessary to investigate the psychological state of individuals who underwent predictive testing for HD, because the psychosocial impact on noncarriers remains unclarified in Japan. Herein, we elucidated the psychosocial impact on the noncarriers for HD and the role of genetic counseling for predictive testing and follow‐up after testing by examining their experiences with predictive testing. We conducted semi‐structured interviews with eight individuals participating in this study. Interview data were transcribed verbatim and evaluated according to thematic analysis. As a result, 4 themes were generated from 21 categories of 46 codes: (1) Diversity of perceptions concerning the test results, (2) Views on life as a noncarrier, (3) Changes in feelings toward and relationships with family members, and (4) Sharing information within the family. After receiving the negative results, the noncarriers felt not only relief but also surprise, doubt, relief from tension, and regret. It was shown that noncarriers felt survivor's guilt toward many unspecified individuals, which was not only a sense of guilt but also a sense of mission or responsibility. Additionally, they conducted altruistic behavior as members of their family and society, that may be related to the Japanese collectivism. Some participants were concerned about sharing information with their siblings. Noncarriers for HD can experience complex psychological states, and Japanese people who prefer high‐context communication may find it difficult to express their feelings and thoughts. It is important to understand their true feelings before and after the predictive genetic testing, reconsider the impact of being a noncarrier and whether it is a burden for them from both subjective and objective perspectives, and conduct long‐term follow‐up as needed.
Interhospital transfer among US veterans admitted to community and veterans affairs hospitals for acute myocardial infarction and ischemic stroke before and during the COVID‐19 pandemic
Authors: Vaughan‐Sarrazin Mary S. , Miell Kelly Richardson , Beck Brice F. , Mecham Bradley , Bailey George , Wardyn Shylo , Mohr Nicholas , Ohl Michael 
Published: October 2024

AbstractBackgroundVeterans Health Administration (VHA) enrollees may use community hospitals for inpatient care and sometimes require transfer to larger community or VHA hospitals. Little is known about interhospital transfer patterns among veterans using community and VHA hospitals or how coronavirus disease 2019 (COVID‐19) case surges affected transfer.MethodsRetrospective cohort study among veterans age 65+ admitted to community and VHA hospitals for acute myocardial infarction (AMI) or acute ischemic stroke (AIS) during 2018–2021. We examined associations between COVID‐19 case density in regional hospital referral networks and the likelihood of transfer.ResultsA total of 8373 (23.6%) veterans with AMI and 4630 (13.1%) with AIS were transferred in the prepandemic period. Transfer was especially common for rural veterans (36% with AMI, 20% with AIS). Most transfers (88%) were between community hospitals and 6% from community to VHA. Among AMI patients, transfer was less likely among patients age >90 (relative to age 65–69), those with non‐White race/ethnicity, and females. Transfer was more common among patients initially seen in rural hospitals (AMI, odds ratio [OR] = 2.73, 95% confidence interval [CI], 2.90–3.74; AIS, OR = 2.43; 95% CI, 2.24–2.65). During 2020–2021, transfer among AMI patients was less likely during COVID‐19 case density surges affecting the admitting hospital's referral network (OR = 0.86; 95% CI, 0.78–0.96 for highest compared with lowest quartile of COVID‐19 cases).ConclusionInterhospital transfer was common for veterans with AMI and AIS, especially among rural veterans. Few transfers were to VHA hospitals. COVID‐19 case surges were associated with decreased transfer for veterans with AMI, potentially limiting access to needed care.