bluuebunny/crossref_metadata_2025_split huggingface dataset:
How should information technology be covered in the accounting program?
Authors: Boulianne Emilio 
Published: November 2016

AbstractProfessional accounting associations, business schools, and accounting professors are increasingly faced with an important question: Which information technology (IT) competencies should be developed in accounting programs to train skilled professional accountants? Key references in accounting education show that advanced‐level training in IT is very important for accountants’ careers. Through content analysis, I investigate how Canadian CPAs are trained in IT. Results indicate that, postmerger, IT has lost ground in the CPA program. This could be mainly due to: (a) a larger coverage in finance, strategy, and governance topics; (b) challenges to promote and teach IT in terms of course development; and (c) a lack of recognition of and incentives for academic work on IT. Compared to some key players in accounting education, it appears that Canada has taken a different route with regard to the required IT competencies. Copyright © 2016 ASAC. Published by John Wiley & Sons, Ltd.
Immune by Heart: Unexpected Observations Inspiring Perspective Therapeutic/Preventive Strategies against Cancer
Authors: Minutolo Filippo 
Published: November 2016

AbstractWe often overlook ordinary events that take place right in front of our eyes. However, such events might be inspiring sources of revolutionary scientific discovery. Simple observations, such as those regarding the substantial immunity of the heart to cancer or the noninvasive behavior of plant tumors, are just the tips of icebergs hiding profound mechanistic causes that deserve deeper investigation. Several current or unprecedented approaches aimed at improving both the prevention and treatment of tumors are discussed on these bases herein. This viewpoint is not intended to give definitive answers, but rather to provide cues for discussion and motivation to pursue unexplored and accessible strategies to fight cancer.
Preoperative assessment of lymph node metastasis in endometrial cancer: A Korean Gynecologic Oncology Group study
Authors: Kang Sokbom , Nam Joo‐Hyun , Bae Duk‐Soo , Kim Jae‐Weon , Kim Moon‐Hong , Chen Xiaojun , No Jae‐Hong , Lee Jong‐Min , Kim Jae‐Hoon , Watari Hidemich , Kim Seok Mo , Kim Sung Hoon , Seong Seok Ju , Kim Ki Tae , Kim Seung Cheol , Kim Jong‐Hyeok , Lim Myung‐Cheol , Lee Jung‐Yun , Ryu Sang‐Young , Yang Bingyi , Kim Byoung‐Gie 
Published: November 2016

BACKGROUNDPreviously proposed criteria for preoperatively identifying endometrial cancer patients at low risk for lymph node metastasis remain to be verified. For this purpose, a prospective, multicenter observational study was performed.METHODSEligible patients with histologically confirmed endometrial cancer underwent magnetic resonance imaging (MRI) and serum cancer antigen 125 (CA 125) testing before surgery. The following criteria were used to identify low‐risk patients: 1) endometrioid‐type cancer, 2) no evidence of deep myometrial invasion on MRI, 3) no enlarged lymph nodes on MRI, 4) no suspicious metastasis out of the uterine corpus, and 5) serum CA 125 levels less than 35 U/mL. Systematic pelvic and/or para‐aortic lymphadenectomy was performed for all patients. The primary endpoint was estimation of the negative predictive value (NPV).RESULTSFrom January 2012 to December 2014, 529 patients from 20 hospitals in 3 Asian countries were consecutively enrolled. According to our criteria, 272 patients (51.4%) were categorized into the low‐risk group. Fifty‐three of the 529 patients (10.0%) had lymph node metastases; these patients included 8 (2.9%) falsely categorized as low‐risk. The sensitivity and specificity of the criteria were 84.9% and 55.5%, respectively. The NPV of 97.1% was higher than the predefined target endpoint of 96%.CONCLUSIONSThe low‐risk criteria based on preoperative tests were confirmed to be reliable and accurate for identifying patients at low risk for lymph node metastasis. These criteria may facilitate patient counseling and surgical decision making. Cancer 2017;123:263–272. © 2016 American Cancer Society.
Second opinions from urologists for prostate cancer: Who gets them, why, and their link to treatment
Authors: Radhakrishnan Archana , Grande David , Mitra Nandita , Bekelman Justin , Stillson Christian , Pollack Craig Evan 
Published: November 2016

BACKGROUNDCancer patients are encouraged to obtain second opinions before starting treatment. Little is known about men with localized prostate cancer who seek second opinions, the reasons why, and the association with treatment and quality of care.METHODSWe surveyed men who were diagnosed with localized prostate cancer in the greater Philadelphia area from 2012 to 2014. Men were asked if they obtained a second opinion from a urologist, and the reasons why. We used multivariable logistic regression models to evaluate the relationship between second opinions and definitive prostate cancer treatment and perceived quality of care.RESULTSA total of 2386 men responded to the survey (adjusted response rate, 51.1%). After applying exclusion criteria, the final analytic cohort included 2365 respondents. Of these, 40% obtained second opinions, most commonly because they wanted more information about their cancer (50.8%) and wanted to be seen by the best doctor (46.3%). Overall, obtaining second opinions was not associated with definitive treatment or perceived quality of cancer care. Men who sought second opinions because they were dissatisfied with their initial urologist were less likely to receive definitive treatment (odds ratio, 0.49; 95% confidence interval, 0.32‐0.73), and men who wanted more information about treatment were less likely to report excellent quality of cancer care (odds ratio, 0.70; 95% confidence interval, 0.49‐0.99) compared with men who did not receive a second opinion.CONCLUSIONSAlthough a large proportion of men with localized prostate cancer obtained a second opinion, the reasons for doing so were not associated with treatment choice or perceived quality of cancer care. Future study is needed to determine when second opinions contribute to increasing the value of cancer care. Cancer 2017;123:1027–34. © 2016 American Cancer Society.
Mesothelium expression of vascular cell adhesion molecule‐1 (VCAM‐1) is associated with an unfavorable prognosis in epithelial ovarian cancer (EOC)
Authors: Scalici Jennifer M. , Arapovic Sanja , Saks Erin J. , Atkins Kristen A. , Petroni Gina , Duska Linda R. , Slack‐Davis Jill K. 
Published: November 2016

BACKGROUNDMesothelium vascular cell adhesion molecule‐1 (VCAM‐1) expression in the metastatic epithelial ovarian cancer (EOC) microenvironment is induced by tumor and mediates tumor cell invasion. VCAM‐1 imaging suggests expression during treatment is an indicator of platinum resistance. Here, we assess the potential prognostic significance of mesothelium VCAM‐1 expression and prospectively evaluate whether soluble VCAM‐1 (sVCAM‐1) is a surrogate for mesothelium expression.METHODSA retrospective review of EOC patients was performed to evaluate outcomes with mesothelium VCAM‐1 expression determined by immunohistochemistry of peritoneum or omentum specimens. A prospective cohort of EOC patients was identified and followed through primary treatment. Serum for sVCAM‐1 evaluation, which was performed via enzyme‐linked immunosorbent assay, was collected before surgery or neoadjuvant chemotherapy and at each treatment cycle. Peritoneal specimens were obtained during debulking to assess mesothelial VCAM‐1 expression.RESULTSA retrospective review identified 54 advanced‐stage EOC patients. Patients expressing mesothelium VCAM‐1 had shortened overall survival (44 vs 79 months, P = 0.035) and progression‐free survival (18 vs 67 months, P = 0.010); the median time to platinum resistance was 36 months for VCAM‐1–expressing patients and not yet determined for the VCAM‐1–negative group. In our prospective observational cohort, 18 EOC patients completed primary treatment; 3 were negative for mesothelium VCAM‐1 expression, and sVCAM‐1 did not vary between groups.CONCLUSIONSMesothelium VCAM‐1 expression is negatively associated with progression‐free and overall survival in EOC. This is especially compelling in light of previous data suggesting that persistent VCAM‐1 expression during treatment is an indicator of platinum resistance. Our pilot study had insufficient cases to determine whether sVCAM‐1 would substitute for mesothelium expression. Cancer 2017;123:977–84. © 2016 American Cancer Society.
Adjuvant chemotherapy versus chemoradiotherapy in the management of patients with surgically resected duodenal adenocarcinoma: A propensity score‐matched analysis of a nationwide clinical oncology database
Authors: Ecker Brett L. , McMillan Matthew T. , Datta Jashodeep , Lee Major K. , Karakousis Giorgos C. , Vollmer Charles M. , Drebin Jeffrey A. , Fraker Douglas L. , Roses Robert E. 
Published: November 2016

BACKGROUNDTo the authors' knowledge, optimal adjuvant approaches for resected duodenal adenocarcinoma are not well established. Given the significant risk of locoregional disease recurrence, there may be a subset of patients who demonstrate an improvement in overall survival (OS) from the addition of radiotherapy (chemoradiotherapy [CRT]) to an adjuvant chemotherapy regimen.METHODSPatients with resected, nonmetastatic duodenal adenocarcinoma who received chemotherapy (694 patients) or CRT (550 patients) were identified in the National Cancer Data Base (1998‐2012). Cox regression identified covariates associated with OS. The chemotherapy and CRT cohorts were matched (1:1) by propensity scores based on the likelihood of receiving CRT or the survival hazard from Cox modeling. OS was compared using Kaplan‐Meier estimates.RESULTSCRT was more frequently used for patients who underwent positive‐margin surgical resection (15.9% vs 9.1%; P<.001). At a median follow‐up of 79.2 months (interquartile range, 52.9‐114.9 months), the median OS of the propensity score‐matched cohort was 46.7 months (interquartile range, 18.9 months to not reached). No survival advantage was observed for patients who were treated with adjuvant CRT compared with those treated with adjuvant chemotherapy (median OS: 48.9 months vs 43.5 months [HR, 1.04; 95% confidence interval, 0.88‐1.22 (P = .669)]). CRT was not found to be associated with a significant improvement in the median OS after positive‐margin surgical resection (133 patients; 27.6 months vs 18.5 months [P = .210]) or in the presence of T4 classification (461 patients; 30.6 months vs 30.4 months [P = .844]) inadequate lymph node staging (584 patients; 40.5 months vs 43.2 months [P = .707]), lymph node positivity (647 patients; 38.3 months vs 34.1 months [P = .622]), or poorly differentiated histology (429 patients; 46.6 months vs 35.7 months [P = .434]).CONCLUSIONSThe addition of radiation to adjuvant therapy does not appear to significantly improve survival, even in high‐risk cases. Cancer 2017;123:967–76. © 2016 American Cancer Society.
Trivium hardware implementations for power reduction
Authors: Mora‐Gutiérrez J. M. , Jiménez‐Fernández C.J. , Valencia‐Barrero M. 
Published: November 2016

SummaryThis paper describes the use of parallelization techniques to reduce dynamic power consumption in hardware implementations of the Trivium stream cipher. Trivium is a synchronous stream cipher based on a combination of three non‐linear feedback shift registers. In 2008, it was chosen as a finalist for the hardware profile of the eSTREAM project. So that their power consumption values can be compared and verified, the proposed low‐power Trivium designs were implemented and characterized in 350‐nm standard‐cell technology with both transistors and gate‐level models, in order to permit both electrical and logical simulations. The results show that the two designs decreased average power consumption by between 15% and 25% with virtually no performance loss and only a slight overhead (about 5%) in area. Copyright © 2016 John Wiley & Sons, Ltd.
Parental strategies used in the family meal session of family‐based treatment for adolescent anorexia nervosa: Links with treatment outcomes
Authors: White Hannah J. , Haycraft Emma , Madden Sloane , Rhodes Paul , Miskovic‐Wheatley Jane , Wallis Andrew , Kohn Michael , Meyer Caroline 
Published: November 2016

ABSTRACTObjectiveExamine relationships between parental mealtime strategies used in the family meal session of family‐based treatment (FBT) and adolescent outcomes at EOT (session 20).MethodEighteen families with an adolescent receiving FBT‐AN participated. Parental strategies during videoed family meals were assessed using a family mealtime coding system. Change scores were calculated for both adolescent %EBW and EDE scores.ResultsIncreased use of parental direct and non‐direct eating prompts during the family meal was associated with greater adolescent weight gain at EOT. Use of parental mealtime strategies was not associated with any significant change in adolescent eating psychopathology at EOT.DiscussionParental verbal eating prompts during the family meal may be effective in promoting short‐term weight gain. During the family meal session, parents should be encouraged to maintain a direct focus on their adolescent child's eating behaviour which may assist their child with food consumption and potential weight gain. Further research examining food‐based interactions among parents and their adolescent child with AN is needed. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2017; 50:433–436)
Biotic interactions mediate the influence of bird colonies on vegetation and soil chemistry at aggregation sites
Authors: Natusch Daniel James Deans , Lyons Jessica Ann , Brown Gregory P. , Shine Richard 
Published: November 2016

AbstractColonial‐nesting organisms can strongly alter the chemical and biotic conditions around their aggregation sites, with cascading impacts on other components of the ecosystem. In tropical Australia, Metallic Starlings (Aplonis metallica) nest in large colonies far above the forest canopy, in emergent trees. The ground beneath those trees is open, in stark contrast to the dense foliage all around. We surveyed the areas beneath 27 colony trees (and nearby randomly chosen trees lacking bird colonies) to quantify the birds' impacts on soil and vegetation characteristics, and to test alternative hypotheses about the proximate mechanisms responsible for the lack of live vegetation beneath colony trees. Nutrient levels were greatly elevated beneath colony trees (especially, those with larger colonies), potentially reaching levels toxic to older trees. However, seedlings thrived in the soil from beneath colony trees. The primary mechanism generating open areas beneath colony trees is disturbance by scavengers (feral pigs and native Turkeys) that are attracted in vast numbers to these nutrient hotspots. Seedlings flourished within exclosures inaccessible to vertebrate herbivores, but were rapidly consumed if unprotected. Our results contrast with previous studies of colonies of seabirds on remote islands, where a lack of large terrestrial herbivores results in bird colonies encouraging rather than eliminating vegetation in areas close to the nesting site. In our continental study system, scavengers may rapidly dilute the spatial heterogeneity generated by the massive nutrient subsidy from bird colonies.
Experimental and analytical study on the performance of particle tuned mass dampers under seismic excitation
Authors: Lu Zheng , Chen Xiaoyi , Zhang Dingchang , Dai Kaoshan 
Published: November 2016

SummaryA particle tuned mass damper (PTMD), which is a creative integration of a traditional tuned mass damper and an efficient particle damper in the vibration control area, is proposed. This paper presents a comprehensive study that involves experimental, analytical, and computational approaches. The vibration control effects of a PTMD that is attached to a five‐story steel frame under seismic input are investigated by a series of shaking table tests. The influence of some parameters (auxiliary mass ratio, gap clearance, mass ratio of particles to the total auxiliary mass, frequency characteristics, and amplitude level of the input) is explored, and the performance of the PTMD with/without buffered material is compared. The experimental results show that the PTMD can achieve significant damping effects under seismic excitations, and the bandwidth of the suppression frequency is expanded, showing the device's robustness and control efficiency. In addition, an approximately analytical solution that is based on the concept of an equivalent single‐particle damper is presented, and the method to determine the corresponding system parameters is introduced. A comparative study between experimental and numerical results is conducted to verify the feasibility and accuracy of this analytical model. Copyright © 2016 John Wiley & Sons, Ltd.
Numerical simulation and seismic performance evaluation of buried pipelines rehabilitated with cured‐in‐place‐pipe liner under seismic wave propagation
Authors: Zhong Zilan , Filiatrault Andre , Aref Amjad 
Published: November 2016

SummaryThe cured‐in‐place‐pipe (CIPP) liner technology involves installation of flexible polymeric composite liners coated with thermosetting resin to the inner surfaces of existing buried pipelines. This innovative technology provides an efficient, economic, and environmentally friendly alternative for rehabilitation of structurally compromised underground pipelines without expensive and disruptive excavation. However, the lack of analytical/numerical procedures to quantify the seismic performance of CIPP liner reinforced pipelines remains a barrier to the seismic design and rehabilitation of underground pipelines. This paper first develops an experimentally validated hysteretic model of ductile iron push‐on joints, reinforced with one particular type of CIPP liner under repeated axial loading. A numerical procedure is then proposed to systematically assess the seismic performance and fragility of straight buried pipelines incorporating push‐on joints and subjected to transient ground deformations. The numerical results indicate that CIPP liner‐reinforced pipelines exhibit favorable robust seismic performance with limited joint damage under high‐intensity transient ground deformations. Copyright © 2016 John Wiley & Sons, Ltd.
Impacts of relative permeability hysteresis on the reservoir performance in CO2 storage in the Ordos Basin
Authors: Li Cai , Zhang Keni , Guo Chaobin , Xie Jian , Zhao Jing , Li Xia , Maggi Federico 
Published: November 2016

AbstractThe CO2 storage reservoir for the Shenhua Carbon Capture and Storage (SHCCS) Demonstration Project in the Ordos Basin in China is known for its low‐permeability and low‐porosity characteristics. However, injectivity was shown by the in situ monitoring data to be substantially increasing over the years. Previous numerical analyses suggest that such reservoir behavior might be mainly attributed to the permeability heterogeneity of the injection layers. As an intermittent injection procedure was actually practiced in this project, the hysteretic behaviors in relative permeability and capillary pressure in the reservoir could be significant. In this study, the hysteretic processes are investigated for a better understanding of the reservoir performance. History‐match is achieved with one order of magnitude lower in the overall permeability of the principal injection layer than the previous simulation. Current calibrated permeability is much closer to seismic measurement and well‐log results. Therefore, we believe that the hysteresis effects accompanying the alternation between injection and injection pause might be another important factor accounting for the observed reservoir performance. It is indicated in this study that, by considering the hysteresis effects in the injection‐pause sequence, an optimally‐designed intermittent injection procedure could greatly improve the injection performance in a saline aquifer with low permeability and low porosity that may seem unfavorable to CO2 storage. © 2016 Society of Chemical Industry and John Wiley & Sons, Ltd.
Cell Microencapsulation by Droplet Microfluidic Templating
Authors: Rossow Torsten , Lienemann Philipp S. , Mooney David J. 
Published: November 2016

Microgels are hydrogel particles with micro‐scale dimensions in the range of 10–1000 µm. They have gained particular importance for cell microencapsulation, because they allow for highly specific creation of a myriad of discrete and miniaturized mimics of the three‐dimensional natural extracellular matrix of tissues. This trend article highlights and critically reviews current droplet‐based microfluidic approaches for the formation of such cell‐laden microgels. It addresses the technical issues of particle formation, the most common polymers used for microgel preparation, and the different types of polymer crosslinking. Furthermore, remaining technical challenges in the field are discussed and perspectives for further development and potential future applications are provided.
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Needleless Electrohydrodynamic Cojetting of Bicompartmental Particles and Fibers from an Extended Fluid Interface
Authors: Jordahl Jacob H. , Ramcharan Stacy , Gregory Jason V. , Lahann Joerg 
Published: November 2016

Electrohydrodynamic cojetting can result in fibers (electrospinning) and particles (electrospraying) with complex, bicompartmental architectures. An important consideration for application of bicompartmental particles and fibers is the limited throughput derived from the use of parallel capillaries, which require laminar flow to form a multifluidic interface. Here, a novel synthesis approach that takes advantage of an extended bicompartmental fluid interface formed at the sharp edge of a 2D plate is reported. Upon application of an electrical potential to the plate, several electrified fluid jets form spontaneously. Depending on the processing conditions, either bicompartmental particles or fibers with well‐defined architectures are prepared. Importantly, this needleless process yields production rates that are more than 30 times higher than those of conventional needle‐based techniques. Fiber properties, such as morphology or size, are independent of the flow rate, indicating that this process is physically self‐regulating by adjusting the number of jets ejecting from the extended fluid interface. The needleless preparation of bicompartmental particles and fibers is an important technological breakthrough that can enable further advances ranging from drug delivery and tissue engineering to industrial applications.
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Blending issues and stakeholders: in pursuit of the elusive synergy
Authors: Mahon John F. , Heugens Pursey P.M.A.R. , McGowan Richard A. 
Published: November 2016

AbstractTwo separate frameworks have existed for the analysis of social predicaments in which businesses play a role: issues management and stakeholder management. In this paper, we argue that the chasm dividing these two literatures is artificial, and potentially obstructive to the advancement of our knowledge of the position of business in contemporary societies. The position we take in the present paper is that all social predicaments have an issues side as well as a stakeholder side and that a dual focus on both issues and stakeholders is therefore essential to understanding the evolution of these predicaments and crucial to managerial dealings with these issues. We present an integrative co‐evolutionary framework, explaining the dynamics between issues and stakeholders in all consecutive stages of a predicament's evolution. The framework proposes a new way of thinking about issues and stakeholders, as such facilitates a deeper understanding of how the social environment of business is constituted, and offers new insights for the practical management of issues and stakeholders.