bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sleep deprivation selectively up-regulates an amygdala-hypothalamic circuit involved in food reward
Authors: Rihm Julia S. , Menz Mareike M. , Schultz Heidrun , Bruder Luca , Schilbach Leonhard , Schmid Sebastian M. , Peters Jan 
Published: January 2018

AbstractSleep loss is associated with increased obesity risk, as demonstrated by correlations between sleep duration and change in body mass index or body fat percentage. Whereas previous studies linked this weight gain to disturbed endocrine parameters after sleep deprivation (SD) or restriction, neuroimaging studies revealed up-regulated neural processing of food rewards after sleep loss in reward-processing areas such as the anterior cingulate cortex, ventral striatum and insula. To tackle this ongoing debate between homeostatic versus hedonic factors underlying sleep loss-associated weight gain, we rigorously tested the association between SD and food cue processing using high-resolution fMRI and assessment of hormones. After taking blood samples from thirty-two lean, healthy men, they underwent fMRI while performing a neuroeconomic, value-based decision making task with snack food and trinket rewards following a full night of habitual sleep (HS) and a night of SD in a repeated-measures cross-over design. We found that des-acyl ghrelin concentrations were increased after SD compared with HS. Despite similar hunger ratings due to fasting in both conditions, participants were willing to spend more money on food items only after SD. Furthermore, fMRI data paralleled this behavioral finding, revealing a food reward-specific up-regulation of hypothalamic valuation signals and amygdala-hypothalamic coupling after a single night of SD. Behavioral and fMRI results were not significantly correlated with changes in acyl, des-acyl or total ghrelin concentrations. Our results indicate that increased food valuation after sleep loss is due to hedonic rather than hormonal mechanisms.
Determination of the Thermodynamics of B-lactoglobulin Aggregation Using Ultra Violet Light Scattering Spectroscopy
Authors: Austerberry James I , Belton Daniel J 
Published: January 2018

AbstractThe problem of protein aggregation is widely studied across a number of disciplines, where understanding the behaviour of the protein monomer, and its behaviour with co-solutes is imperative in order to devise solutions to the problem. Here we present a method for measuring the kinetics of protein aggregation based on ultra violet light scattering spectroscopy (UVLSS) across a range of NaCl conditions. Through measurement of wavelength dependant scattering and using the model protein β-lactoglobulin, it is possible to isolate the thermodynamic contributions to thermal unfolding. We show that increasing NaCl concentration decreases the free energy of unfolding which is dominated by the decrease of the enthalpy contribution. This contribution is significantly larger than the decrease in change in entropy observed at higher salt concentrations between the folded and unfolded states.
Brazilian nursing professionals: leadership to generate positive attitudes and behaviours
Authors: Araujo Claudia Affonso Silva , Figueiredo Kleber Fossati 
Published: January 2018

PurposeThis paper aims to identify the kind of work environment that should be offered by hospital leaders to their nursing staff in Brazil to generate job satisfaction, organizational commitment and organizational citizenship behaviour within their field of expertise.Design/methodology/approachA survey was applied to 171 nurses and 274 nursing technicians who work at five private hospitals in Brazil. Both factor analysis and regression analysis were used to analyse the study model.FindingsThe results indicate that to stimulate positive behaviours and attitudes among nursing staff, managers should mainly be concerned about establishing a clear and effective communication with their professionals to ensure role clarity, promote a good working environment and encourage relationships based on trust.Research limitations/implicationsThe limitations of the study are absence of the researcher while the questionnaires were filled out and the fact that the sample comprised respondents who made themselves available to participate in the research.Practical implicationsThis study contributes to elucidate the factors that can promote a good internal climate for nursing staff, assisting hospital leaders to face the huge managerial challenges of managing, retaining and advancing these professionals.Originality/valueThe findings contribute to the body of knowledge in leadership among nursing professionals in developing countries. Hospital leaders in Brazil should encourage trusting relationships with nursing professionals through clear, effective and respectful communications, besides investing in team development and promoting a good working environment.
Synthesis, application and antibacterial activity of new reactive dyes based on thiazole moiety
Authors: Mohamed Fatma A. , Abd El-Megied Saadia A. , Bashandy Mahmoud S. , Ibrahim Hassan M. 
Published: January 2018

Purpose
This study aims to synthesise and characterise new reactive dyes based on thiazole derivatives which act as chromophoric moieties. These dyes were applied to cotton fabric, resulting in the dyed fabrics exhibiting good colour strength, light fastness and other fastness properties. The antibacterial activity of the dyed cotton fabric was evaluated against gram-negative and gram-positive bacteria.

Design/methodology/approach
The dyes were synthesised in two steps. First, the coupling compound was formed by adding H-acid solution to cyanuric chloride in an ice bath at pH 5 then adding 4-aminobenzenesulphonic acid portion-wise at room temperature and at pH 6-7. Second, different diazonium salts 4-phenylthiazol-2-amine (2a) and 4-(4-methoxyphenyl) thiazol-2-amine (2b) were coupled with the coupling compound at pH 5. The resultant monochlorotriazine (MCT)-reactive dyes (6a, 6b) were formed. The synthesised dyes were applied onto cotton fabric under typical exhaust dyeing conditions and their dyeing properties were investigated.

Findings
High antimicrobial activity, dye exhaustion and fixation yield on cotton fabric were recorded for each dye. All dyes showed high stability against washing, rubbing, perspiration and light fastness.

Research limitations/implications
Dyeing of cotton fabric with these dyes which have higher fastness, higher exhaustion and higher antibacterial activity is considered one of the most important reactive dyes species.

Practical implications
The preparation procedure showed the synthesis of the novel MCT-reactive dyes derived from thiazole derivatives followed by the application of these dyes on cotton fabrics.

Social implications
Use of reactive dyes will bring a number of benefits to society including higher fastness and higher antibacterial activity so, and these dyes can be used for dyeing cotton.

Originality/value
In this work, the new reactive dyes derived from thiazole derivatives were synthesised and their structures were confirmed by the analytical and spectral data. Such compounds are considered to be excellent reactive dyes with different colour shades and higher antibacterial activity.
Relation of work-life balance, work-family conflict, and family-work conflict with the employee performance-moderating role of job satisfaction
Authors: Soomro Aqeel Ahmed , Breitenecker Robert J. , Shah Syed Afzal Moshadi 
Published: January 2018

PurposePeople in both the developing and developed worlds now face issues like work-to-family and family-to-work conflicts. Accordingly, the purpose of this paper is to explore the relationships between work-life balance, work-family conflict, and family-work conflict and perceived employee performance with job satisfaction serving as a moderating variable.Design/methodology/approachThe object of this study is a full-time teaching faculty. Responses from 280 young university teaching faculty serving in public-sector universities in Islamabad, Pakistan, were investigated by applying linear regression analysis to test six hypotheses.FindingsThe results show that work-life balance and work-family conflict have a positive effect on employee performance. Job satisfaction has moderating effects on the relationships between work-life balance, work-family conflict, and family-work conflict with perceived employee performance.Originality/valueThe study presents some unique results, which are different from previous studies such as work-family conflict has a positive significant effect on employee performance, family-work conflict has no significant effect on employee performance, and job satisfaction can be a negative moderator between these relations.
Understanding health consumer value: service marketing perspective
Authors: Islam Shahidul 
Published: January 2018

Purpose
The purpose of this paper is to clarify and explain patient-centered health choices, facilitating health-care providers’ service orientation.

Design/methodology/approach
Extensive literature review has been done to extract seven constructs (five dimensions of SERVQUAL, perceived service cost (PSC), and reference) and their underlying 28 items to be quantified. A survey of 201 health consumers was conducted to rate those variables and their constructs. Descriptive statistics and structural equation modeling are utilized to delineate and explicate factors.

Findings
The confirmatory factor analysis demonstrated that responsiveness has the highest predictive power in explaining hospital choice intention. However, PSC, the only construct, is not statistically significant. The models are considered to have satisfactory reliability, validity, and acceptable fit.

Research limitations/implications
Since the study was administered in Comilla city, the generalizations should be exploited carefully. Future studies can be carried out on the behavioral patterns of patients and attitudes of health-care providers with respect to the discussed factors and variables.

Practical implications
The result highlights patients’ service expectations that can be carefully and creatively applied in the service marketing program, improving doctors’ and nurses’ service orientation, developing physical evidence, and managing references to communicate service value to patients.

Originality/value
What health consumers emphasize and how they incorporate service quality dimensions into hospital choice intention has stayed almost unexplored in the existing literature in Bangladesh. This study provides valuable insights into the meaning of patients’ choices, which will help practitioners and researchers to formulate marketing strategies that improve health-care outcomes and are acceptable to patients.
Effect of board characteristics on firm value: evidence from India
Authors: Mishra Rakesh Kumar , Kapil Sheeba 
Published: January 2018

PurposeThe purpose of this paper is to explore the relationship of board characteristics and firm performance for Indian companies.Design/methodology/approachCorporate governance structures of 391 Indian companies out of CNX 500 companies listed on National Stock Exchange have been studied for their impact on performance of companies. Structural equation modeling methodology has been employed on data for five financial years from 2010 to 2014 for selected companies. Market-based measure (Tobin’sQ) and accounting-based measure (return on asset) have been employed for measuring firm performance.FindingsEmpirical findings indicate that there is significant positive association between board size and firm performance. Board independence is found significantly related to firm performance. Number of board meetings is found to be sending positive signal to the market creating firm value. Separation of CEO and chairman of the board is found to be value creating and overburdened directors affect firm performance adversely. Findings also suggest that the governance-performance relationship is also dependent upon the type of performance measures used in the study.Research limitations/implicationsLimitations of this study are in terms of data methodology and possible omission of some variables. It is understood that the qualitative dynamics happening inside board meetings impact corporate performance. The strategic decisions-making process adopted by the boards to fight competition or to increase market share is not available in public domain easily. The decision-making processes and monitoring for implementation of these decisions could impact corporate governance-performance relationship. These parameters and their impact on corporate performance are not covered under the scope of the present study. However, the same could have thrown more light on governance-performance relationship.Originality/valueThe paper adds to the emerging body of literature on corporate governance-performance relationship in the Indian context using a reasonably wider and newer data set.
Mediating role of innovativeness between risk taking and performance in Indian universities
Authors: Gupta Manish , Acharya Anitha 
Published: January 2018

PurposeWith increased globalization, Indian universities are struggling to attract and retain talented academics and are exploring the ways to enhance their service performance and brand image (BI). However, there is a paucity of studies that view universities through the corporate lens. Therefore, the purpose of this paper is to examine the mediating role of innovativeness in the relationships of creativity, risk taking (RT), and performance in service delivery (PSD). Another objective is to find out how this nexus affects universities’ BI.Design/methodology/approachResponses were collected from 280 academics working for different Indian universities. Structural analysis was performed to examine the relationships under investigation.FindingsThe results indicate that innovativeness fully mediates the positive RT – PSD relationship and that PSD positively influences BI.Research limitations/implicationsThe findings of this study mainly augment the theory of BI by empirically linking BI and its antecedents in the context of Indian universities.Practical implicationsFor enhancing a university’s BI, management is encouraged to promote RT work culture along with innovative and creative teaching methods.Originality/valueThis study is one of the few studies in India that see academia through the corporate lens. Also, it provides evidence for the importance innovativeness in enhancing BI of a university.
Decoding willingness of Indian consumers to pay a premium on green products
Authors: Kirmani Mohd Danish , Khan Mohammed Naved 
Published: January 2018

PurposeThe purpose of this paper is to identify the relevant antecedents of willingness of Indian consumers to pay a premium for green products and empirically validate the relationship between these antecedents and willingness to pay (WTP).Design/methodology/approachData were generated from 515 students enroled in various educational institutions approved by the All India Council for Technical Education and located in New Delhi and National Capital Region region of India. A combination of researcher-controlled and systematic sampling techniques was employed for the purpose of identifying the sample. Structural equation modelling was used to analyse the data using AMOS 20.0.FindingsThe study revealed that attitude towards green products (ATGP) has a significant and positive influence on WTP. Additionally, collectivism and environmental concern emerged as predictors of ATGP.Practical implicationsMarketing practitioners are expected to get deeper insights into reasons that contribute to the formation of positive attitude among Indian consumers towards green products. This understanding may greatly assist proactive marketers in developing appropriate strategies to increase the propensity of WTP a premium for such products.Originality/valueThe study is pioneering in the sense that the construct WTP for green products had relatively been less explored in the Indian context. The construct WTP is important for Indian consuming class which is dominated by middle and lower middle income groups for whom spending extra from their regular expenditure is a critical and sensitive issue.
Evaluation of viral contamination in a baculovirus expression system
Authors: Ono Chikako , Hirano Junki , Okamoto Toru , Matsuura Yoshiharu 
Published: January 2018

ABSTRACTInsect expression systems based on baculovirus are widely used for generating recombinant proteins. Here, the infectivity of baculoviruses under the physiological stresses of ‘freeze–thaw’ and sonication and the baculoviral contamination of recombinant proteins after protein purification were evaluated. Our findings suggest that Nonidet P‐40 (NP‐40) treatment of baculoviruses completely abolishes their infectivity and that recombinant proteins purified with affinity beads do not include infectious baculoviruses. We therefore suggest that baculovirus is completely inactivated by NP‐40 treatment and that recombinant proteins are unlikely to be contaminated with infectious baculoviruses after their affinity purification.
Utility of three novel insulin resistance‐related lipid indices for predicting type 2 diabetes mellitus among people with normal fasting glucose in rural China
Authors: Wang Bingyuan , Zhang Ming , Liu Yu , Sun Xizhuo , Zhang Lu , Wang Chongjian , Li Linlin , Ren Yongcheng , Han Chengyi , Zhao Yang , Zhou Junmei , Pang Chao , Yin Lei , Feng Tianping , Zhao Jingzhi , Hu Dongsheng 
Published: January 2018

AbstractBackgroundInexpensive and easily measured indices are needed for the early prediction of type 2 diabetes mellitus (T2DM) in rural areas of China. The aim of this study was to compare triglyceride glucose (TyG), visceral adiposity (VAI), and lipid accumulation product (LAP) with traditional individual measures and their ratios for predicting T2DM.MethodsData for 11 113 people with baseline normal fasting glucose in a rural Chinese cohort were followed for a median of 6.0 years. Cox proportional hazards regression was used to calculate covariate‐adjusted hazard ratios (aHRs) and 95% confidence intervals (95% CIs) and receiver operating characteristic analysis was used to compare the ability of traditional measures and TyG, VAI, and LAP at baseline to predict T2DM at follow‐up.ResultsAmong individual measures, fasting plasma glucose (FPG) and waist circumference (WC) were strongly associated with T2DM. Of all lipid ratios, an elevated triglycerides (TG) to high‐density lipoprotein cholesterol (HDL‐C) ratio was associated the most with T2DM. Compared with the first quartiles of TyG, VAI, and LAP, their fourth quartiles were associated with T2DM for men (aHR 3.54 [95% CI 2.08–6.03], 2.89 [1.72–4.87], and 5.02 [2.85–8.85], respectively) and women (6.15 [3.48–10.85], 4.40 [2.61–7.42], and 6.49 [3.48–12.12], respectively). For predicting T2DM risk, TyG, VAI, and LAP were mostly superior to the TG:  HDL‐C ratio, but did not differ from FPG and WC.ConclusionsPrediction of T2DM was not improved by TyG, VAI, and LAP versus FPG or WC alone. Therefore, TyG, VAI, and LAP may not be inexpensive tools for predicting T2DM in rural Chinese people.
Sovereign Debt Restructuring in Europe
Authors: Buchheit Lee C. , Mitu Gulati G. 
Published: January 2018

AbstractThe Eurozone sovereign debt crisis began in the spring of 2010. Seven years on seems like an appropriate point at which to critique how the crisis has been handled and to assess whether policy changes will be required should it flare up again. In particular, there are a number of lessons to be learned from the Greek debt restructuring of 2012.
Land management change greatly impacts biofuels’ greenhouse gas emissions
Authors: Qin Zhangcai , Canter Christina E. , Dunn Jennifer B. , Mueller Steffen , Kwon Hoyoung , Han Jeongwoo , Wander Michelle M. , Wang Michael 
Published: January 2018

AbstractHarvesting corn stover for biofuel production may decrease soil organic carbon (SOC) and increase greenhouse gas (GHG) emissions. Adding additional organic matter into soil or reducing tillage intensity, however, could potentially offset this SOC loss. Here, using SOC and life cycle analysis (LCA) models, we evaluated the impacts of land management change (LMC), that is, stover removal, organic matter addition, and tillage on spatially explicit SOC level and biofuels’ overall life cycle GHG emissions in US corn–soybean production systems. Results indicate that under conventional tillage (CT), 30% stover removal (dry weight) may reduce baseline SOC by 0.04 t C ha−1 yr−1 over a 30‐year simulation period. Growing a cover crop during the fallow season or applying manure, on the other hand, could add to SOC and further reduce biofuels’ life cycle GHG emissions. With 30% stover removal in a CT system, cover crop and manure application can increase SOC at the national level by about 0.06 and 0.02 t C ha−1 yr−1, respectively, compared to baseline cases without such measures. With contributions from this SOC increase, the life cycle GHG emissions for stover ethanol are more than 80% lower than those of gasoline, exceeding the US Renewable Fuel Standard mandate of 60% emissions reduction in cellulosic biofuels. Reducing tillage intensity while removing stover could also limit SOC loss or lead to SOC gain, which would lower stover ethanol life cycle GHG emissions to near or under the mandated 60% reduction. Without these organic matter inputs or reduced tillage intensity, however, the emissions will not meet this mandate. More efforts are still required to further identify key practical LMCs, improve SOC modeling, and accounting for LMCs in biofuel LCAs that incorporate stover removal.
Common Primary and Secondary Causes of Headache in the Elderly
Authors: Sharma Tara L. 
Published: January 2018

Objective/BackgroundHeadache in the elderly, defined as individuals aged 65 and older, although less prevalent than younger individuals, can present as a diagnostic challenge, given the increase in potentially fatal diseases within this population.MethodsThese individuals require a complete history, neurological examination, and assessment of potential secondary causes of headaches.ResultsSecondary causes include temporal or giant cell arteritis, subdural hematomas, central nervous system (CNS) tumors, strokes, and CNS infections. Once secondary conditions are ruled out, then primary causes of headache are considered such as tension‐type headache, migraine, cluster headache, or hypnic headache.ConclusionThis article reviews the distinguishing characteristics of the most common types of headache in patients over the age of 65 years old, along with potential diagnostic tests and treatment.
Environmental resistance of Cr2AlC MAX phase under thermal gradient loading using a burner rig
Authors: Gonzalez‐Julian Jesus , Go Teresa , Mack Daniel E. , Vaßen Robert 
Published: January 2018

AbstractDense Cr2AlC materials were tested under a gradient loading for the first time using a burner rig. The severe thermal cycling conditions consist of 500 short cycles at 1200°C, with an accumulative time at the maximal temperature of more than 29 hours. The samples showed no visible damage under these conditions due to the formation of an outer protective α‐Al2O3 layer, which shows a strong adhesion with the Cr2AlC substrate. No cracks, delamination or damage were observed at the interface between the different layers. This excellent response under cyclic loading shows the excellent potential of Cr2AlC compounds for high‐temperature applications.