bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solvation Effect‐Determined Mechanisms of Cation Exchange Reactions for Efficient Multicomponent Nanocatalysts
Authors: Liu Shangheng , Wang Xiaocan , Huang Wei‐Hsiang , Zhang Qiugen , Han Jiajia , Zhang Yingtian , Pao Chih‐Wen , Hu Zhiwei , Xu Yong , Huang Xiaoqing 
Published: October 2024

AbstractCation exchange (CE) reaction is a classical synthesis method for creating complex structures. A lock of study on intrinsic mechanism limits its understanding and practical application. Using X‐ray absorption spectroscopy, we observed that the evolution from Ru−Cl to Ru−O/OH occurs during the CE between K2RuCl6 and CoSn(OH)6 in aqueous solution, while CE between K2PtCl6 and CoSn(OH)6 is inhibited due to the failure of structural evolution from Pt−Cl to Pt−O/OH. Theoretical simulations imply that the interaction between Ru−O and CoSn(OH)6 with Co vacancy (CoVCoSn(OH)6) endows the electron transfer, as a result of strengthened adsorption on CoVCoSn(OH)6. Moreover, this mechanism is validated for CE between K2RuCl6 and ASn(OH)6 (A=Mg, Ca, Mn, Co, Cu, Zn), and CE between K2PdCl6/Na3RhCl6/K2IrCl6 and CoSn(OH)6. Impressively, the Pt‐free CoRuSn(OH)x produced via CE displays a mass activity and a power density of 15.0 A mgRu−1 and 11.6 W mgRu−1, respectively, for anion exchange membrane fuel cell (AEMFC) exceeding the values of commercial PtRu/C (11.8 A mgRu+Pt−1 and 9.0 W mgRu+Pt−1). This work, for the first time, reveals the intrinsic mechanism of CE as structural evolution of target ion breaking through the traditional classic etch‐adsorption mechanism and will promote fundamental research and practical application in various fields.
Integrated Omnidirectional Design of Non‐Volatile Solid Additive Enables Binary Organic Solar Cells with Efficiency Exceeding 19.5 %
Authors: Wang Ya‐Ting , Sun Wen‐Jing , Zhang Yamin , Zhang Bo‐Yang , Ding Yun‐Tao , Zhang Ze‐Qi , Meng Lingxian , Huang Kexin , Ma Wei , Zhang Hao‐Li 
Published: October 2024

AbstractSolid additives have drawn great attention due to their numerous appealing benefits in enhancing the power conversion efficiencies (PCEs) of organic solar cells (OSCs). To date, various strategies have been reported for the selection or design of non‐volatile solid additives. However, the lack of a general design/evaluation principles for developing non‐volatile solid additives often results in individual solid additives offering only one or two efficiency‐boosting attributes. In this work, we propose an integrated omnidirectional strategy for designing non‐volatile solid additives. By validating the method on the 4,5,9,10‐pyrene diimide (PyDI) system, a novel non‐volatile solid additive named PyMC5 was designed. PyMC5 is capable of enhancing device performance by establishing synergistic dual charge transfer channels, forming appropriate interactions with active layer materials, reducing non‐radiative voltage loss and optimizing film morphology. Notably, the binary device (PM6 : L8‐BO) treated by PyMC5 achieved a PCE over 19.5 %, ranking among the highest reported to date. In addition, the integration of PyMC5 mitigated the degradation process of the devices under photo‐ and thermal‐stress conditions. This work demonstrates an efficient integrated omnidirectional approach for designing non‐volatile solid additives, offering a promising avenue for further advancements in OSC development.
Solvent Polarity‐Induced Regulation of Cation Solvation Sheaths for High‐Voltage Zinc‐Based Batteries with a 1.94 V Discharge Platform
Authors: Jin Xuting , Lai Guobin , Xiu Xinyi , Song Li , Li Xiangyang , Dai Chunlong , Li Meng , Quan Zhonggui , Tang Bin , Shao Gonglei , Zhang Zhipan , Liu Feng , Qu Liangti , Zhou Zhen 
Published: October 2024

AbstractTo address the challenge of low discharge platforms (<1.5 V) in aqueous zinc‐based batteries, highly concentrated salts have been explored due to their wide electrochemical window (~3 V). However, these electrolytes mainly prevent hydrogen evolution and dendrite growth at the anode without significantly enhancing voltage performance. Herein we introduce an approach by adjusting solvent polarity to regulate cation solvation sheaths in hybrid electrolytes, reducing Zn/Zn2+ oxidation potential and water activity. Through strong cation‐water coordination and hydrogen bonding between dimethylsulfoxide and water, the designed electrolyte, at a low concentration, achieves a broader electrochemical window (4 V) than conventional concentrated electrolytes. Using this electrolyte, a Zn/Zn battery showed an impressive cycle life of 4340 cycles, while a Zn/lithium manganate battery delivered a high discharge platform of over 1.9 V with exceptional cycling stability. A Zn‐based micro‐battery with a polyvinyl alcohol‐based hybrid electrolyte also achieved a record‐high discharge platform of 1.94 V. This work presents a promising strategy for developing low‐concentration electrolytes for high‐performance sustainable energy storage.
Adjustment of temperature sensitivity using hydrophilic materials to develop superabsorbent polymers based on poly(N‐isopropyl acrylamide) as a temperature‐sensitive material
Authors: Chen Diming , Ou Baoli , Ma Lifang 
Published: October 2024

AbstractPoly(N‐isopropyl acrylamide) (PNIPAm) is a temperature‐sensitive material with a fast temperature response and a low critical solubilization temperature (LCST) of approximately 32°C, but it swells only 20–40 times after absorbing water. To enhance its water‐absorption properties, we introduced hydrophilic monomers into the NIPAm monomer to prepare a ternary copolymerized superabsorbent polymer. In addition, we characterized this copolymer using various techniques and analyzed its temperature‐sensitive and water‐absorbing properties. The results showed that the optimal synthesis conditions consisted of m(NIPAm):m(AMPS) = 4, 1.5% initiator, 0.3% cross‐linking agent, and 1.0% quaternized ammonium chitosan, which ensured the significant temperature sensitivity of the water‐absorbent resin. Under these conditions, the swelling ratio of the water‐absorbing resin reached 235.3 times, the LCST value was 44.6°C, the water retention rate was 84.9% at 25°C after 12 h, and the shrinkage ratio reached 81.7% at 60°C after 3 h, and 97.6% after 12 h. The resulting material could be rapidly dehydrated at high temperatures and presented clear temperature‐sensitive characteristics while maintaining excellent water‐absorbing properties.
Interceptive abilities in autism spectrum disorder: Comparing naturalistic and virtual visuomotor tasks
Authors: Park Se‐Woong , Cardinaux Annie , Crozier Dena , Russo Marta , Bond Sabrina , Kjelgaard Margaret , Sinha Pawan , Sternad Dagmar 
Published: October 2024

AbstractA growing body of research reveals that autistic individuals exhibit motor coordination challenges. Multiple theoretical frameworks propose that the seemingly disparate features of autism may arise from a common underlying process: a diminished ability to make predictions. Sensorimotor skills, such as catching a ball, critically rely on predicting the ball's trajectory as well as anticipatory coordination of the entire body. Here, we assessed four different naturalistic and virtual interception tasks with 31 neurotypical and 23 autistic children (ages 7–12). In a naturalistic setting, participants caught the ball either with their hands or a hand‐held funnel with an enlarged catch area that also prevented the ball from bouncing off. A virtual setup reduced whole‐body demands, as children only moved a paddle to catch or bounce a ball on a screen. Control tasks, involving rapid reaching to grasp a static object and quiet standing, which largely eliminated the requirements for prediction, were also tested. Results from all task variations demonstrated that autistic children completed fewer successful interceptions, suggesting that predictive requirements, inherent to all interception tasks, played a critical role. Effect sizes in the virtual tasks were smaller. Correlations of the task metrics with behavioral assessments rendered the strongest correlations with Praxis scores. The control tasks showed no differences between autistic and neurotypical children. These findings lend support to the emerging hypothesis that predictive challenges are present in autism. Further research with larger sample sizes will help identify to what extent these visuomotor differences may inform core domains of autism.
Prenatal exposure to hypoxic risk conditions in autistic and neurotypical youth: Associated ventricular differences, sleep disturbance, and sensory processing
Authors: Preciado Cristian , Baida Maria , Li Yi , Li Yan , Demopoulos Carly 
Published: October 2024

AbstractThere is a growing body of research that suggests conditions during the period of pregnancy and birth can affect how autism spectrum disorder (ASD) presents itself. This study aimed to investigate the incidence of oxygen deprivation during this period known as prenatal and perinatal hypoxic risk (HR) conditions in ASD compared with neurotypical control (NTC) youth. We also examined ventricular morphology variations associated with HR exposure, and to evaluate associations with clinical symptoms. Results from a cohort of 104 youth revealed a higher incidence of exposure to prenatal hypoxic conditions in the ASD group. Additionally, ASD individuals with prenatal hypoxic exposure (ASD + HR) demonstrated larger third ventricle volumes compared with both ASD and NTC individuals without such exposure (ASD‐HR and NTC‐HR, respectively). Furthermore, associations were identified between prenatal hypoxic exposure, third ventricle volume, sensory dysfunction, and severity of sleep disturbances. These findings suggest exposure to prenatal hypoxic risk conditions may exacerbate or modify the neurodevelopmental trajectory and symptom severity in ASD, emphasizing the need for better prenatal care and specific interventions to reduce these risks.
Electrolyte‐free cathode design for solid‐state batteries demonstrated with bifunctional Li2VCl4
Authors: Kasahara Takuma , Song Peng , Honma Itaru , Ohno Saneyuki 
Published: October 2024

AbstractAll‐solid‐state batteries have attracted much attention because of the expected high energy density and inherent safety stemming from their nonflammable property. While improving the energy density of the cathode poses a significant challenge, here we introduce a novel battery design strategy to enhance energy density by employing bifunctional cathode material, allowing the weight ratio of the active material to be increased without using an electrolyte for the cathode. By employing lithium‐containing vanadium halide Li2VCl4, serving as both active material and electrolyte, the all‐solid‐state battery cell with no electrolyte for the cathode with a capacity approaching the theoretical limit is demonstrated. In addition, we present a guideline for improving capacity retention from the perspective of interfacial stability. Notably, thermodynamic analysis revealed interfacial instability between Li2VCl4 and sulfide material. A double‐layer separator, incorporating halide materials for the cathode side, was implemented to enhance the interfacial stability and mitigate the capacity degradation. Furthermore, it was found that the rate capability depends on the lithium content in synthesized Li2‐xVCl4 and does not change with the state of charge significantly. This study will contribute to designing the bifunctional cathode material for an all‐solid‐state battery and describe its unique properties.
Transcriptional Downregulation of Methanol Metabolism Key Genes During Yeast Death in Engineered Pichia pastoris
Authors: Wang Chenbo , Jiang Wei , Yu Chang , Xia Jianye 
Published: October 2024

ABSTRACTPichia pastoris possesses the unique ability to utilize methanol as its sole carbon source, which makes it a proper host for producing various high‐value‐added products via metabolic engineering. Nevertheless, cell death has been observed during the fermentation of modified P. pastoris, with limited literature elucidating the underlying causes and mechanisms. Understanding the death mechanisms during methanol‐based fermentation is crucial for optimizing fermentation strategies, enhancing the accumulation of target products, and reducing production costs. Here, we first sought to eliminate the potential causes of cell death during fermentation, such as inadequate inorganic salts and toxic by‐product accumulation. The elimination of these potential causes was achieved efficiently utilizing the high‐throughput fermentation equipment. Subsequently, we established a correlation between yeast cell death and the duration of the methanol metabolism period by monitoring the growth of the yeast at different fermentation stages. A critical revelation from this work came from analyzing the yeast's transcriptomic data at various stages of methanol metabolism. It was observed that a significant characteristic of yeast cell death during fermentation was the marked down‐regulation of transcript levels of key enzymes involved in the methanol assimilation pathway and genes related to their biosynthesis process. The findings of this work are crucial for better understanding the causes and mechanisms of cell death for engineered P. pastoris during methanol‐utilized fermentation.
Do gender diversity and foreign investor affect sustainability disclosure
Authors: Widjaja Jahja Hamdani , Joni Joni , Riyanto Naomi Fani 
Published: October 2024

AbstractWe examine the effect of female board members and foreign institutional investors on corporate social responsibility (sustainability) disclosure in Indonesian listed firms from 2015 to 2017. Our final sample comprised 1192 firm‐year observations. We apply ordinary least squares pool regression to estimate the associations and address the endogeneity problem using the two‐stage least squares model, generalized method of moments, and lagged variables. While previous studies have focused on the impact of female board members and foreign institutional investors on financial outcomes, we extend the literature by investigating the association between both female board members and foreign investors and sustainable disclosure in Indonesia, where the participation of women is nominal, especially at the top management level, and the level of foreign ownership is high. Our findings propose a proportion of women as board members for listed firms and promote attractive policies to increase the number of foreign investors investing in Indonesia. It also contributes to conflicting results regarding the relationship between corporate governance and corporate social responsibility (CSR) commitment. Our results were robust after testing for endogeneity and adding more control variables. Overall, the findings have practical implications for policymakers and investors regarding corporate disclosure and governance in Indonesia.
Sustainable development and firm value: How ESG performance shapes corporate success—a systematic literature review
Authors: Li Xuan , Saat Maisarah Mohamed , Khatib Saleh F. A. , Liu Yang 
Published: October 2024

AbstractThis study is designed to conduct a systematic literature review aimed at assessing the influence of environmental, social, and governance (ESG) performance on firm value. Although previous studies have explored their relationship, a comprehensive systematic review on this topic is still lacking. We conducted a detailed literature search in the Scopus and Web of Science databases and identified 73 papers published between 2016 and 2023 as the sample, covering annual trends, country and industry distribution, theoretical frameworks, proxy variables, research methods, research results, and provided direction for future research. We found a significant increase in the number of studies over the past 3 years. Cross‐country studies dominated the field, with most research adopting multi‐industry analysis, while studies focusing on a single industry were relatively rare. The stakeholder theory and agency theory were the most widely applied theories. Most studies showed that ESG performance had a positive effect on firm value, reflecting the growing importance that markets and investors placed on ESG performance and its contribution to long‐term firm growth. However, some studies reported negative or insignificant effects, noting that the effects of ESG performance varied by industry, region, and market environment. This study suggests that future research should explore the independent and interactive effects of each ESG dimension on firm value, focusing on dynamic relationships across industries and regions, using new methods and models, and incorporating moderating variables. This study provides practical guidance for firm managers and policymakers to optimize ESG practices, enhancing firm value and promoting sustainability.
Thiazepine‐Based Hybrids as Promising Anti‐Colon Cancer Agents: Design, Synthesis, Computational and In Vitro Screening
Authors: Vaghasiya Mahesh D. , Sain Arindam , Mendapara Jigarkumar V. , Khamrai Dipshikha , Naskar Debdut , Kumari Premlata 
Published: October 2024

AbstractNovel thiazepine‐based hybrids (9 a–d) were designed and synthesized to create lead molecules with exceptional anti‐colon cancer efficacy. Analytical methods, including IR, NMR, and HR‐MS, characterized the synthesized compounds. The in vitro colorectal study was carried out to compare the biological activity of newly developed compounds with the computational data. The tested compounds induced cytotoxicity in HT‐29 cells for both 24 h and 48 h in a dose‐dependent manner. However, compound 9 a induced cytotoxicity at much higher concentrations compared to the rest of the compounds. 9 b and 9 c caused 50 % cell death (compared to the untreated cells) at a dose of ~50 μM and 40 μM in case of 24‐hour exposure, respectively. On the contrary, for 48 h exposure, both 9 b and 9 c induced 50 % cell death concerning untreated cells at a dose of around ~20 μM, whereas 9 d exhibited 50 % cell death at 5 μM in the case of 48 h exposure. In silico ADMET was also carried out to understand the pharmacokinetics and safety profiles of the drug candidates. We found some of the critical targets of these compounds, which eventually will be integral to exploring the mechanistic actions of these compounds in colon cancer.
Optimizing Activity and Stability in AgCl‐CuO Electrocatalysts: Insights from Different Morphologies for Enhanced ORR Performance
Authors: Yatheendran Anagha , Nachimuthu Koushik Kumar , George Ashna , Sandhyarani N. 
Published: October 2024

AbstractHighly enduring and methanol‐tolerant electrocatalysts are pertinent to revolutionizing direct methanol fuel cell (DMFC) technologies. Transition‐metal‐based electrocatalysts are anticipated to rank among the remarkable electrocatalysts for boosting the sluggish oxygen reduction reaction (ORR) kinetics. In this study, we report a facile approach to optimize the activity and stability of the AgCl‐CuO systems. The tailored nanoparticle–nanorod (NP–NR) and nanoleaf (NL) like morphologies deliver remarkable bifunctional catalytic performance for oxygen reduction and hydrogen evolution reactions, sustained activity, and comparatively better stability for ORR. A meager shift of only 0.014 and 0.024 V in the half‐wave potential is observed in the NP‐NR and NL structures, respectively, for the ORR even after 2500 cycles. Furthermore, both the AgCl‐CuO composite exhibit an excellent tolerance to methanol.
Structural Regulation of a Multi‐Component Co2P2O7‐MoN/NC Electrocatalyst for Efficient Oxygen Evolution Reaction
Authors: Jin Man , Zou Yan , Shi Bo‐Cong , Tang Yu‐Jia , Liu Ting‐Ting , Liu Li‐Ming , Geng Dongsheng 
Published: October 2024

AbstractRealizing efficient and durable non‐precious metal‐based electrocatalysts for oxygen evolution reaction (OER) still remains a great challenge. Here, a multi‐component composite of Co2P2O7‐MoN/NC containing pyrophosphate, nitride, and nitrogen‐doped carbon is successfully prepared via a facile two‐step synthesis method. Combining the structural regulation between the active metal‐ and non‐metal‐based species, Co2P2O7‐MoN/NC demonstrates superior activity and durability for OER, requiring an overpotential of 278 mV at a current density of 10 mA cm−2, a Tafel slope of 83.3 mV dec−1, and long‐term stability over 100 h in an alkaline solution. Post‐characterizations reveal that synergistic effect among stable Co2P2O7, partially dissolved MoN, N‐doped carbon, and new‐formed CoOOH nanosheets enable structural reconstruction, fast charge transfer, and formation of oxygen‐containing intermediates, promoting the OER performance significantly. This work provides a promising pathway to tune multi‐components to fabricate efficient transition‐metal‐based electrocatalysts in energy conversion applications.
Tumor Cell‐Specific Metabolic Labelling of Surface Sialoglycans and Post‐Click with Multivalent Rhamnose Enable Precise Immune Killing by Endogenous Antibody
Authors: Hong Haofei , Li Yanchun , Li Dan , Lin Han , Zhao Jie , Wang Zheng , Wu Zhimeng 
Published: October 2024

Comprehensive SummaryWe report the design and development of a β‐glucuronidase (β‐Glu)‐responsive ManNAz derivative, Glu‐AAM, for tumor‐selective metabolic glycoengineering. Glu‐AAM enables specific labeling of tumor cell surface sialoglycans in the presence of overexpressed β‐Glu in cancer cells, including breast, leukemia, and colorectal cancer cells. We demonstrate the high selectivity and efficiency of Glu‐AAM‐mediated metabolic glycoengineering across multiple cancer cell lines. Furthermore, we synthesized multivalent antibody‐recruiting molecules (DBCO‐Rha) that can be covalently attached to the azido‐modified tumor cell surface, leading to potent antibody‐dependent cellular phagocytosis and complement‐dependent cytotoxicity. The octameric DBCO‐Rha8 construct exhibited the most effective immune response. This integrated strategy of β‐Glu‐responsive metabolic glycoengineering and antibody‐recruiting immunotherapy provides a promising platform for targeted cancer therapies and expands the toolbox of metabolic glycoengineering for cancer immunotherapy.
Metastatic Upper Thoracic Intramedullary Spinal Cord Tumor of Ovarian Adenocarcinoma: A Rare Case Report and Literature Review
Authors: Heidari Vahid , Mollahoseini Reza , Golchin Navid , Karimi Hadi , Hoseini Mohammad , Kazemi Benyamin , Zolfeghari Elmira , Ashayeri Ahmadabad Hemin 
Published: October 2024

ABSTRACTBackgroundIntramedullary spinal cord metastasis (ISCM) is uncommon and usually occurs in advanced malignancies. Effective management methods are not clearly defined, and the outcomes of current treatments vary. Currently, there is no universal strategy for managing patients with intramedullary spinal metastases.CaseTo the best of our knowledge, we present a case of ovarian adenocarcinoma that was managed surgically in a 70‐year‐old woman with metastasis to the upper thoracic spinal cord, and we assess pertinent literature and deliberate management approaches.ConclusionsProgression in early diagnosis and advanced therapeutic methods for ISCMs have contributed to the increased incidence and prevalence of this condition. There is no established consensus regarding the definitive patient management methods. Consequently, we offer multidisciplinary management with individualization based on the patient's functional status, requirement for a definitive diagnosis for potential additional adjuvant therapies, and assessment of the extent of systemic disease, which can influence the desired quality of life and survival duration.