bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexually satiated male uses gustatory-to-neuropeptide integrative circuits to reduce time investment for mating
Authors: Jae Kim Woo , Gee Lee Seung , Auge Anne-Christine , Yeh Jan Lily , Nung Jan Yuh 
Published: November 2016

ABSTRACTMales rely on a ‘time investment strategy’ to maximize reproductive success. Here we report a novel behavioral plasticity whereby male fruit flies exhibit a shortened mating duration when sexually satiated, which we named ‘Shorter-Mating-Duration (SMD)’. SMD requires the sexually dimorphic Gr5a-positive neurons for detecting female body pheromones. The memory circuitry within the ellipsoid body (EB) and mushroom body (MB) brain regions is crucial for SMD, which depends on the circadian clock genesClockandcycle, but nottimelessorperiod. SMD also relies on signaling via the neuropeptide sNPF, but not PDF or NPF. Sexual experience modifies the neuronal activity of a subset of sNPF-positive neurons involved in neuropeptide signaling, which modulates SMD. Thus, our study delineates the molecular and cellular basis for SMD – a plastic social behavior that serves as a model system to study how the brain switches the internal states between sexual drive and satiety.
Detecting hierarchical 3-D genome domain reconfiguration with network modularity
Authors: Norton Heidi K. , Huang Harvey , Emerson Daniel J. , Kim Jesi , Gu Shi , Bassett Danielle S. , Phillips-Cremins Jennifer E. 
Published: November 2016

AbstractMammalian genomes are folded in a hierarchy of topologically associating domains (TADs), subTADs and looping interactions. The nested nature of chromatin domains has rendered it challenging to identify a sensitive and specific metric for detecting subTADs and quantifying their dynamic reconfiguration across cellular states. Here, we apply graph theoretic principles to quantify hierarchical folding patterns in high-resolution chromatin topology maps. We discover that TADs can be accurately detected using a Louvain-like locally greedy algorithm to maximize network modularity. By varying a resolution parameter in the modularity quality function, we accurately partition the mouse genome across length scales into a hierarchical nested structure of network communities exhibiting a wide range of sizes. To distinguish high probability subTADs from the full detected set, we developed and applied a new ‘hierarchical spatial variance minimization’ method. Moreover, we identified a large number of dynamically altered communities between pluripotent embryonic stem cells and multipotent neural progenitor cells. Cell type specific boundaries correlate with trends in dynamic occupancy of the architectural protein CTCF, thereby validating their biological relevance. Together, these data demonstrate the utility of metrics from network science in quantifying a nested hierarchy of dynamic 3D chromatin communities across length scales. Our findings are significant toward unraveling the link between higher-order genome folding and gene expression during healthy development and the deregulation of molecular pathways linked to disease.
Predator phylogenetic diversity decreases predation rate via antagonistic interactions
Authors: MacDonald A. Andrew M. , Romero Gustavo Q. , Srivastava Diane S. 
Published: November 2016

AbstractBackground:Predator assemblages can differ substantially in their top-down effects on community composition and ecosystem function, but few studies have sought to explain this variation in terms of the phylogenetic distance between predators. The effect of a local predator assemblage will depend on three things – which predators tend to co-occur, how similar their prey preferences are, and how they interact with each other and the whole community. Phylogenetic distance between predators may correlate with each of these processes, either because related predators are more likely to share the same traits, and therefore have similar habitat and prey preferences, or because predators are more likely to compete, and therefore diverge in habitat and prey preferences. Therefore, the phylogenetic structure of predator assemblages could provide a unifying framework for predicting how predators will impact their prey - and therefore any ecosystem functions mediated by their prey.Methods:We examined the effects of predators on macroinvertebrate food webs found in bromeliads, combining field observations, laboratory feeding trials and a manipulative experiment. We determined whether the phylogenetic distance between predators could explain: the co-observed occurrence of predator species among bromeliads, overlap in prey preferences under no-choice conditions, and effects of predator composition on prey survival, prey composition and ecosystem processes.Results:We found that phylogenetic distance does not predict either the co-occurrence of predator species nor the overlap in their prey preferences. However, our manipulative experiment showed that prey mortality decreased as the phylogenetic distance between predator species increased, reflecting antagonistic interactions among more distant predators. These effects of phylogenetic distance on prey mortality did not translate into effects on ecosystem function, as measured by rates of detrital decomposition and nitrogen cycling.Discussion:We conclude that the effects of predator phylogenetic diversity on the bromeliad food web are primarily determined by antagonistic predator-predator interac-tions, rather than habitat distribution or diet overlap. This study illustrates the potential of a phylogenetic community approach to understanding food webs dynamics.
Profiling immunoglobulin repertoires across multiple human tissues by RNA Sequencing
Authors: Mangul Serghei , Mandric Igor , Yang Harry Taegyun , Strauli Nicolas , Montoya Dennis , Rotman Jeremy , Der Wey Will Van , Ronas Jiem R. , Statz Benjamin , Yao Douglas , Zelikovsky Alex , Spreafico Roberto , Shifman Sagiv , Zaitlen Noah , Rossetti Maura , Mark Ansel K. , Eskin Eleazar 
Published: November 2016

AbstractAssay-based approaches provide a detailed view of the adaptive immune system by profiling immunoglobulin (Ig) receptor repertoires. However, these methods carry a high cost and lack the scale of standard RNA sequencing (RNA-Seq). Here we report the development of ImReP, a novel computational method for rapid and accurate profiling of the immunoglobulin repertoire from regular RNA-Seq data. ImReP can also accurately assemble the complementary determining regions 3 (CDR3s), the most variable regions of Ig receptors. We applied our novel method to 8,555 samples across 53 tissues from 544 individuals in the Genotype-Tissue Expression (GTEx v6) project. ImReP is able to efficiently extract Ig-derived reads from RNA-Seq data. Using ImReP, we have created a systematic atlas of 3.6 million Ig sequences across a broad range of tissue types, most of which have not been studied for Ig receptor repertoires. We also compared the GTEx tissues to track the flow of Ig clonotypes across immune-related tissues, including secondary lymphoid organs and organs encompassing mucosal, exocrine, and endocrine sites, and we examined the compositional similarities of clonal populations between these tissues. The Atlas of Immunoglobulin Repertoires (The AIR), is freely available athttps://github.com/smangul1/TheAIR/wiki, is one of the largest collection of CDR3 sequences and tissue types. We anticipate this recourse will enhance future immunology studies and advance the development of therapies for human diseases. ImReP is freely available athttps://github.com/mandricigor/imrep/wiki
Traces of equality policy and diversity management in Finnish work organizations
Authors: Ylöstalo Hanna 
Published: November 2016

Purpose
The purpose of this paper is to discuss how equality and diversity are experienced in everyday work within Finnish work organizations and how equality policy and diversity management participate in maintaining the inequality regimes of the organizations.

Design/methodology/approach
The empirical findings are based on 31 interviews, which were collected in two private sector work organizations. Inequality regimes, the interlocked practices, and processes that result in continuing inequalities in all work organizations, are used as an analytic tool.

Findings
There is an individualizing tendency of equality in Finnish work organizations, which is also the premise of diversity management. Accordingly, the organizations cannot address structural and historical discrimination based on gender, race, and class. Also, when diversity is intrinsic to the corporate image, the members of the organization downplay and legitimize inequalities in their organization.

Originality/value
The paper analyzes inequality regimes in a context that should be ideal for equality and diversity: Finland, where gender equality policies are relatively progressive, and organizations that strive for equality and diversity. This gives new insight on why inequalities are difficult to change.
Connectivity, cost-efficiency, community and collaboration
Authors: Kyrö Riikka , Peltokorpi Antti , Artto Karlos 
Published: November 2016

Purpose
This paper aims to increase understanding on how co-locating in a multi-firm campus setting could be of value to healthcare organizations.

Design/methodology/approach
The paper presents a qualitative case study of two health campuses in Finland. The data comprises interviews with different organizations operating on the campuses, complemented by onsite observations, and analysis of archival data.

Findings
Based on the empirical analysis, the value of co-locating as perceived by the organizations operating on campus is grouped into four categories: connectivity, cost-efficiency, community and collaboration (or the “four Cs”).

Research limitations/implications
The study does not aim at statistical genaralizability but rather seeks to draw analytical generalizations based on identified empirical regularities. The developed value framework, the four Cs, contributes to current scholarly knowledge on location strategies.

Practical implications
Furthermore, the managerial implications of the four Cs entail a new twofold role for property management: the traditional facilitator role, which is suitable for delivering the two tangible values of connectivity and cost-efficiency, and the modern era integrator, a community builder that is able to deliver community and collaboration.

Originality/value
Previous literature on healthcare facilities has focused on the technical performance of the buildings, while previous literature on the collaborative value of co-location has studied mainly single-firm corporate campuses. This study uniquely explores the potential value of health campuses, where different private, public and third sector organizations co-locate.
Performance measurement tool (PMT) to control maintenance-associated infections
Authors: Njuangang Stanley , Lasanthi Liyanage Champika , Akintoye Akintola 
Published: November 2016

Purpose
Healthcare maintenance (HM) services have an important role in the control of hospital-acquired infections (HAIs). Notwithstanding, many HM managers still do not measure the performance of HM services in infection control (IC). This research, therefore, aims to establish the level of importance of critical success factors (CSFs) and performance measures in HM IC. A performance measurement tool (PMT) was also developed to improve the performance of the HM unit in IC.

Design/methodology/approach
The CSFs and performance measures identified in the literature were categorised into the four perspectives of balanced scorecard and analysed through Delphi. The Delphi participants were presented with 67 performance measures and asked to rate their level of importance in HM in IC. In total, they identified 53 important performance measures to control maintenance-associated HAIs. The results obtained from the Delphi study were used to categorise the performance measures into four means zones. The mean zones were assigned weights (1-4), and the level of importance of the CSFs was established through weighted average. Liaison and communication, IC practices and maintenance resource availability emerged as the most important CSFs in HM in IC. Conversely, customer satisfaction emerged as the least important. Information gathered about the CSFs and performance measures was used to develop a PMT in HM in IC.

Findings
The following CSFs, liaison and communication, IC practices and maintenance resource availability, emerged as the most important in HM in IC. Conversely, customer satisfaction emerged as the least important. Information gathered about the CSFs and performance measures was used to develop a PMT in HM in IC.

Originality/value
Through the application of the PMT, performance in IC can be estimated at different levels in the HM unit. The PMT allows managers to focus on the most crucial CSFs and performance measures that drive performance in HM in IC. The PMT could also be used for benchmarking purposes.
Thermal analysis of natural convection and radiation in a fully wet porous fin
Authors: Darvishi M.T. , Gorla Rama Subba Reddy , Khani F. , Gireesha B.J. 
Published: November 2016

Purpose
The purpose of this paper is to take the thermal analysis of natural convection and radiation heat transfer in fully wet porous fins. The wet porous fins taken for the analysis are straight fins in nature and wet. Their profile being straight helps heat transfer process of fins faster. The analysis is performed using the Darcy’s model to generate the heat equation to analyze the variation of convection and radiation parameters. The porous nature of the fins allows the flow to penetrate through the porous material of the fins leading to solid-fluid interface. The obtained non-dimensional ordinary differential equation involving three highly nonlinear terms are solved numerically by using spectral collocation method after which they are reduced into algebraic equations using Chebyshev polynomials. The study is analyzed using the mathematical analysis on heat equation and generating graphs for finding the parameters important to the heat transfer in the straight fins.

Design/methodology/approach
This study is performed using Darcy’s model to formulate heat transfer equation. To study the thermal performance, the authors considered a finite length fin with insulated tip. The effects of the wet fin parameter m2, porosity parameter Sh, radiation parameter G and temperature ratio CT on the dimensionless temperature distribution and heat transfer rate are discussed.

Findings
The results show that the base heat flow increases when the permeability of the medium is high and/or when the buoyancy effect induced in the fluid is strong.

Research limitations/implications
The analysis is made for the Darcy’s model. Non-Darcy effects will be investigated in a future work.

Practical implications
The approach is useful in enhancing heat transfer rates.

Originality/value
The results of the study will be interest to the researchers of the field of heat exchanger designers.
Unsteady viscous MHD flow over a permeable curved stretching/shrinking sheet
Authors: Pop Ioan , Mohamed Isa Siti Suzilliana Putri , Arifin Norihan M. , Nazar Roslinda , Bachok Norfifah , Ali Fadzilah M. 
Published: November 2016

PurposeThe purpose of this paper is to theoretically study the problem of the unsteady boundary layer flow past a permeable curved stretching/shrinking surface in the presence of a uniform magnetic field. The governing nonlinear partial differential equations are converted into ordinary differential equations by similarity transformation, which are then solved numerically.Design/methodology/approachThe transformed system of ordinary differential equations was solved using a fourth-order Runge-Kutta integration scheme. Results for the reduced skin friction coefficient and velocity profiles are presented through graphs and tables for several sets of values of the governing parameters. The effects of these parameters on the flow characteristics are thoroughly examined.FindingsResults show that for the both cases of stretching and shrinking surfaces, multiple solutions exist for a certain range of the curvature, mass suction, unsteadiness, stretching/shrinking parameters and magnetic field parameter.Originality/valueThe paper describes how multiple (dual) solutions for the flow reversals are obtained. It is shown that the solutions exist up to a critical value of the shrinking parameter, beyond which the boundary layer separates from the surface and the solution based upon the boundary layer approximations is not possible.
Women’s entrepreneurship in Iran
Authors: Modarresi Meisam , Arasti Zahra , Talebi Kambiz , Farasatkhah Maghsoud 
Published: November 2016

Purpose
The purpose of this paper is to identify the growth motivations of women owning and managing home-based businesses (HBBs) in Iran.

Design/methodology/approach
The qualitative approach was used by 20 in-depth interviews with Iranian female HBBs owners/mangers.

Findings
The business growth motivations of women owning and managing HBBs were categorized in intrinsic and extrinsic motivations. Results show that women owning and managing HBBs are motivated to growth their businesses by intrinsic motivations including need for achievement, need for independence, proving competency and socio-cultural concerns. Also, they are motivated by some extrinsic motivations including financial issues, fame, positive feedback from others and the problems of working at home.

Research limitations/implications
Given the importance of entrepreneurial growth, the findings provide additional insight into growth motivations of women entrepreneurs.

Practical implications
The results of this study can help policymakers to develop purposeful growth policies for women’s HBBs that are commensurate with the motivations.

Social implications
Also, women owning and managing HBBs themselves could better concentrate on enhancing business growth by deepening their understanding of their business growth motivations.

Originality/value
The paper contributes to the scarce knowledge about women-owned HBBs in Iran, a rapidly growing, developing country, which can provide better insights from a less explored context. Moreover, as there is only a limited understanding of HBB growth, especially in relation to women business owners, the study results can prove helpful for researchers in the domain of female entrepreneurs. Also, this paper contributes to theory on the motivation for entrepreneurship and to research on growth motivation.
The use of mobile phones to support women’s entrepreneurship in the Arab countries
Authors: Ameen Nisreen A. , Willis Rob 
Published: November 2016

Purpose
This paper aims to investigate how mobile phones can be used to support women’s entrepreneurship in Arab countries. The objective is to explore new ways to close the gender gaps in terms of entrepreneurship in these countries.

Design/methodology/approach
The methodology used in this research is an in-depth analysis of the existing literature and recent reports on women’s entrepreneurship and on the adoption and use of mobile phones in Arab countries.

Findings
The findings of this research indicate that female Arab entrepreneurs are interested in using mobile phones. However, they have not yet realised the full potential of mobile technology in empowering them beyond its basic use. Several challenges facing women entrepreneurship in the Arab countries were identified. Mobile phones can be used to overcome these challenges.

Research limitations/implications
This research is based on the collection and analysis of secondary data rather than primary data to support the findings.

Practical implications
There is a need for collaboration between telecommunication companies operating in the Arab region and government initiatives to build a solid environment in which female Arab entrepreneurs can operate.

Originality/value
This research provides new insights and recommendations for reducing the gender gaps in terms of entrepreneurship by using new and improved techniques to address women’s needs for economic independence. This will also increase the profit gained by the telecommunication companies operating in Arab countries and bring additional income to this region.
Convection heat transfer and temperature analysis of oil jet lubricated spur gears
Authors: Wang Yanzhong , Niu Wentao , Chen Yanyan , Song Guanhua , Tang Wen 
Published: November 2016

Purpose
This paper aims to provide an analytic technique for determining the convection heat transfer and temperature of oil jet lubricated spur gears.

Design/methodology/approach
A multiphase flow model is developed to calculate the convection heat transfer coefficients on different gear faces during different contact conditions. The frictional heat is calculated and a method to distribute between the two gears is developed. A finite element model is established to calculate the temperatures in both meshing and cooling processes.

Findings
The convection heat transfer coefficients on different surfaces are obtained successfully. Area-related formulae are developed to calculate the heat distribution coefficients. The gear temperature reaches a maximum at the beginning of meshing, then reduces and gets minimum at pitch point, after that it increases again. The gear temperature descends rapidly to steady temperature during the short time of jet cooling process. The tendency of computational results coincides well with the experimental results.

Originality/value
The research presented here could be used in the design phase of the jet lubricated spur gears. The precise temperature is obtained to assess the thermal capacity of gears, from which the gear parameters and oil supply conditions could be adjusted and designed.
Team psychological safety and team learning: a cultural perspective
Authors: Cauwelier Peter , Ribière Vincent M. , Bennet Alex 
Published: November 2016

Purpose
The purpose of this paper was to evaluate if the concept of team psychological safety, a key driver of team learning and originally studied in the West, can be applied in teams from different national cultures. The model originally validated for teams in the West is applied to teams in Thailand to evaluate its validity, and the views team members have on the antecedents of team psychological safety are analyzed.

Design/methodology/approach
The core of the sequential explanatory mixed method research was an experiment with nine teams from a single engineering organization (three teams from each the USA, France and Thailand). Team learning behaviors were analyzed from the conversations between team members. Team psychological safety was analyzed through a quantitative instrument and one-on-one structured interviews with each team member.

Findings
The results showed that the original model is confirmed for the teams from the USA and France but not confirmed for teams from Thailand. The thematic analysis of the one-on-one interviews highlights important differences between teams from the USA and France on the one hand and teams from Thailand on the other hand when it comes to the role of the team manager and the views that team members have on the diversity between them.

Originality/value
This research confirms that the concept of team psychological safety, and its impact on the way teams learn, needs to be adjusted if it is to be applied to teams in countries with national cultures different from those prevalent in the West. The implications are that researchers who develop theories in the social sciences field should evaluate how cultural differences impact their models, and that managers who implement learning and solutions should take national cultural differences into consideration.