bluuebunny/crossref_metadata_2025_split huggingface dataset:
The dynamics of searching for meaning and presence of meaning in daily life
Authors: Newman David B. , Nezlek John B. , Thrash Todd M. 
Published: April 2017

AbstractObjectiveResearch on searching for meaning in life has focused on trait‐level relationships rather than within‐person relationships. Our goal was to examine within‐person relationships between daily states of searching for meaning in life, daily states of presence of meaning in life, and daily states of well‐being.MethodTo advance our understanding of searching for meaning in life, we conducted a daily diary study with two samples in which 254 undergraduate students (Mage = 18.54, SD = 1.55; 66.9% female) completed daily reports of presence and search for meaning in life and well‐being for 2 weeks (n = 3,288).ResultsBetween persons, search was negatively related to presence and well‐being. In contrast, within persons, daily search was positively related to presence and well‐being. Relationships between daily search and daily well‐being were mediated by daily presence of meaning in life. Lagged analyses indicated that greater search on one day led to greater presence the next day.ConclusionsThe implications of these within‐person findings suggest that researchers should reconsider the potential consequences that occur from searching for meaning in life, including the possibility that greater searching is associated with increased well‐being.
A diagnostic algorithm for assessment of liver fibrosis by liver stiffness measurement in patients with chronic hepatitis B
Authors: Cai Y.‐J. , Dong J.‐J. , Wang X.‐D. , Huang S.‐S. , Chen R.‐C. , Chen Y. , Wang Y.‐Q. , Song M. , Chen Y.‐P. , Li Z. , Zhou M.‐T. , Shi K.‐Q. 
Published: April 2017

SummarySteatosis could affect liver stiffness measurement in patients with nonalcoholic fatty liver disease and chronic hepatitis C. In this study, we aimed to investigate the impact of steatosis on liver stiffness in hepatitis B virus (HBV)‐infected patients and develop a diagnostic algorithm for prediction of liver fibrosis by liver stiffness based on the controlled attenuation parameter. A total of 488 HBV‐infected patients who underwent clinical examination, Fibroscan and liver biopsy were prospectively enrolled. The best liver stiffness measurement (kPa) cut‐offs for significant fibrosis (S≥3) and advanced fibrosis (S≥4) were 8.1 and 10.9, respectively. The best controlled attenuation parameter cut‐off for severe steatosis (≥30%) was 287 dB/m. Among patients with low‐grade fibrosis (S0‐S2/S0‐S3), mean liver stiffness values were significantly higher in subjects with severe steatosis or controlled attenuation parameter ≥287 dB/m compared with those without. Moreover, in subjects with low‐grade fibrosis, a higher rate of false‐positive rate was observed in patients with severe steatosis than those in patients without (F0‐F2: 28.2% vs 9.7%; F0‐F3: 17.0% vs 5.3%), and in patients with CAP≥287 dB/m compared with their counterpart (F0‐F2: 23.7% vs 9.2%; F0‐F3: 14.1% vs 4.8%). Low‐grade fibrosis was accurately identified by γ‐glutamyl transpeptidase‐to‐platelet ratio (GPR) with a cut‐off value of 0.17. In patients with GPR<0.17, similar results were observed. The presence of steatosis may lead to overestimation of fibrosis assessed by liver stiffness measurement in patient with chronic hepatitis B. A diagnostic algorithm for assessing fibrosis using liver stiffness was developed by combining both controlled attenuation parameter and GPR values.
Temporospatial dynamics and public health significance of bacterial flora identified on a major leatherback turtle (Dermochelys coriacea) nesting beach in the Southern Caribbean
Authors: Phillips Ayanna Carla N. , Coutou Johanna , Rajh Stacy , Stewart Neville , Watson Antonio , Jehu Adam , Asmath Hamish , Dziva Francis , Unakal Chandrashekhar , Holder Ridley , Carthy Raymond Raoul 
Published: April 2017

AbstractGrande Riviere beach, on the island of Trinidad, supports the largest nesting population of leatherback turtles in the Caribbean region. Throughout the nesting season, nests are naturally disturbed by newly nesting females, resulting in egg breakage and loss of some nest viability. This environment is ideal for the growth and proliferation of microorganisms. The range of bacterial flora present in beach sand and egg shells was examined, with emphasis on bacteria that may pose a threat to public and animal health. The extent to which the bacterial load and genera on the beach changed throughout the season was also assessed. Twenty‐five genera were identified, with Pseudomonas spp. found to be the most predominant environmental bacteria. Four genera identified possess zoonotic potential, while five additional genera are known to be of public and animal health significance. Distinct shifts in the density and distribution of bacteria were observed along the beach from early to peak nesting season. Shifts were seen across heavily traversed zones, thus highlighting the potential exposure threats posed to beach visitors and animals alike. Further studies aimed at speciating this population of bacteria, as well as isolating potential fungal pathogens may mitigate this threat. Identification of bacterial agents that are specifically pathogenic to leatherback turtles, turtle eggs, hatchlings and those who may interact with these animals will serve to enhance and guide efforts to better conserve this species and protect the health of all who visit this ecologically significant site.
Culture, demography and biogeography of sponge science: From past conferences to strategic research?
Authors: Schönberg Christine Hanna Lydia 
Published: April 2017

AbstractPerceived changes in the culture of sponge science and sponge conferences served as motivation for an evaluation of the sponge science community and research, over time and at present. Observed changes included a decrease in proceedings publications on sponge fossils and freshwater sponges, sponges from temperate environments, review papers and data syntheses, frequency of aquarium studies, and number of species investigated per publication. Publications on recent sponges, hexactinellids, calcareans, marine, Indo‐Pacific and warm‐water sponges increased, as well as the number of authors per publication and the proportion of field studies. Studies at the level of specimens and ultrastructure were gradually replaced by molecular approaches, but studies at the community level remained stable. The five sub‐disciplines morphology/taxonomy, phylogeny/evolution, physiology, ecology and faunistics also retained about equal proportions over time. Conference publications related to taxonomy, phylogeny and biodiversity prevailed, whereas those on management and conservation were rare, possibly because studies on sponge recovery, survival and mortality were also scarce. The community of sponge scientists has grown and become more diverse over time, presently representing 72 nations. The gender distribution evened out since the first sponge conference and presently favours women at early and men at late career stages. Although stated research interests are generally dominated by physiology and ecology, taxonomy and evolution are favoured after retirement. Sponge science has become more dynamic, but maybe also more competitive and less inclusive. We now face the dual challenge of safeguarding against the loss of some sub‐disciplines, and fostering the collaborative, helpful culture characteristic of sponge science.
Population ecology of the snail Melampus bidentatus in changing salt marsh landscapes
Authors: Zajac Roman , Kelly Erin , Perry Danielle , Espinosa Ivana 
Published: April 2017

AbstractWe studied the population ecology of the snail Melampus bidentatus in relation to patch composition and landscape structure across several salt marsh systems in Connecticut, USA. These marshes have changed significantly over the past 40–50 years including loss of total area, increased areas of short Spartina alterniflora, and decreased areas and fragmentation of Spartina patens. These changes are consistent with tidal inundation patterns that indicate frequent flooding of high marsh areas. Melampus bidentatus densities were highly variable, both among different salt marsh systems and locations within specific marshes, but were generally similar among short Sp. alterniflora and Sp. patens patches within locations. Densities were lowest where the marsh was regularly inundated at high tide and only remnant Sp. patens patches remained. Almost no snails were found in bare patches. Areas that had large Sp. patens patches adjacent to short Sp. alterniflora supported the highest M. bidentatus densities. Population size‐structure varied significantly among patch types, with higher proportions of large individuals in short Sp. alterniflora and hummocked Sp. patens patches than in large and remnant Sp. patens patches. This was likely due to size‐selective predation and/or higher snail growth rates due to better food resource conditions in short Sp. alterniflora patches. Egg mass densities and the number of eggs per egg mass were highest in short Sp. alterniflora. Our results indicate that M. bidentatus is resilient to the level and patterns of salt marsh change evident at our study sites. Indeed, snail densities were significantly higher than reported in other field studies, suggesting that increased patch areas of short Sp. alterniflora and associated environmental conditions at our study sites may provide more favorable habitats than previously when marshes were dominated by extensive Sp. patens meadows. However, there may be threshold conditions that could overwhelm the ability of M. bidentatus to maintain itself within salt marsh systems where changes in hydrology, sedimentation and other factors lead to increased numbers of bare patches and ponds and loss of short Sp. alterniflora and Sp. patens. Studies of the responses of resident and transient fauna to salt marsh change are critically needed in order to better understand the implications for salt marsh ecosystem dynamics and services.
A note on the long rate in factor models of the term structure
Authors: de Kort Jan 
Published: April 2017

AbstractIn this paper, we consider factor models of the term structure based on a Brownian filtration. We show that the existence of a nondeterministic long rate in a factor model of the term structure implies, as a consequence of the Dybvig–Ingersoll–Ross theorem, that the model has an equivalent representation in which one of the state variables is nondecreasing. For two‐dimensional factor models, we prove moreover that if the long rate is nondeterministic, the yield curve flattens out, and the factor process is asymptotically nondeterministic, then the term structure is unbounded. Finally, we provide an explicit example of a three‐dimensional affine factor model with a nondeterministic yet finite long rate in which the volatility of the factor process does not vanish over time.
Insular bats and research effort: a review of global patterns and priorities
Authors: Conenna Irene , Rocha Ricardo , Russo Danilo , Cabeza Mar 
Published: April 2017

Abstract

Evidence‐based knowledge is critical for the delineation and success of conservation interventions. However, despite limited research resources, research efforts frequently fail to target conservation priorities. Island endemic bats (IEBs) are a poorly studied group inhabiting some of the world's most vulnerable habitats, and for which no review of research allocation has ever been conducted.

We conducted a bibliometric review to evaluate the global research patterns for IEBs with respect to individual species, geographical distribution and the International Union for Conservation of Nature (IUCN) Red List categories. Additionally, we studied the relationship between the number of publications and changes in Red List category, and identified species‐based and area‐based priorities for future research.

IEBs are significantly more threatened than bat species that are not island endemics. However, research focusing on IEBs is scarce, centred on species of lesser conservation concern, and spatially asymmetric, overlooking areas of high IEB biodiversity. Conservation‐oriented research seems to target species facing high extinction risk, but is extremely thinly and unevenly distributed. Although we found a positive association between research effort and improvement in Red List category, an increase in extinction risk did not trigger more scientific attention. A prioritisation analysis highlighted, as the top five islands for species richness in the least‐studied and highest conservation concern IEBs: Sulawesi, Timor, New Guinea, Java, and Borneo. The ten species of highest research priority include threatened and Data Deficient species from Southeast Asian and Pacific islands.

Conservation‐oriented research seems to be too scarce to satisfy conservation needs. The observed mismatch between research allocation and conservation priorities may reflect the fact that highly endangered species are unattractive targets for fund‐raising, due to species crypticity, high research budget requirements, and high risk of project failure. However, our findings support the importance of research for the conservation of IEBs, and we therefore advocate that more attention is directed towards the least‐known species.
Quantitative depth‐resolved microcirculation imaging with optical coherence tomography angiography (Part ΙΙ): Microvascular network imaging
Authors: Gao Wanrong 
Published: April 2017

AbstractIn this work, we review the main phenomena that have been explored inOCTangiography to image the vessels of the microcirculation within living tissues with the emphasis on how the different processing algorithms were derived to circumvent specific limitations. Parameters are then discussed that can quantitatively describe the depth‐resolved microvascular network for possible clinical diagnosis applications. Finally, future directions in continuingOCTdevelopment are discussed.
A Mixed User‐Equilibrium and System‐Optimal Traffic Flow for Connected Vehicles Stated as a Complementarity Problem
Authors: Bagloee Saeed Asadi , Sarvi Majid , Patriksson Michael , Rajabifard Abbas 
Published: April 2017

AbstractConnected vehicles (CVs), be they autonomous vehicles or a fleet of cargo carriers or Uber, are a matter of when they become a reality and not if. It is not unreasonable to think that CV technology may have a far‐reaching impact, even to the genesis of a completely new traffic pattern. To this end, the literature has yet to address the routing behavior of the CVs, namely traffic assignment problem (TAP) (perhaps it is assumed, they ought to follow the traditional shortest possible paths, known as user equilibrium [UE]). It is possible that real‐time data could be derived from the vehicles’ communications that in turn could be used to achieve a better traffic circulation. In this article, we propose a mathematical formulation to ensure the CVs are seeking the system optimal (SO) principles, while the remainder continue to pursue the old‐fashioned UE pattern. The model is formulated as a nonlinear complementarity problem (NCP). This article contributes to the literature in three distinct ways: (i) mathematical formulation for the CVs’ routing, stated as a mixed UE‐SO traffic pattern, is proposed; (ii) a variety of realistic features are explicitly considered in the solution to the TAP including road capacity, elastic demand, multiclass and asymmetric travel time; and (iii) formal proof of the existence and uniqueness of the solutions are also presented. The proposed methodology is applied to the networks of Sioux‐Falls and Melbourne.
TgPL2, a patatin‐like phospholipase domain‐containing protein, is involved in the maintenance of apicoplast lipids homeostasis in Toxoplasma
Authors: Lévêque Maude F. , Berry Laurence , Yamaryo‐Botté Yoshiki , Nguyen Hoa Mai , Galera Marine , Botté Cyrille Y. , Besteiro Sébastien 
Published: April 2017

SummaryPatatin‐like phospholipases are involved in numerous cellular functions, including lipid metabolism and membranes remodeling. The patatin‐like catalytic domain, whose phospholipase activity relies on a serine‐aspartate dyad and an anion binding box, is widely spread among prokaryotes and eukaryotes. We describe TgPL2, a novel patatin‐like phospholipase domain‐containing protein from the parasitic protist Toxoplasma gondii. TgPL2 is a large protein, in which the key motifs for enzymatic activity are conserved in the patatin‐like domain. Using immunofluorescence assays and immunoelectron microscopy analysis, we have shown that TgPL2 localizes to the apicoplast, a non‐photosynthetic plastid found in most apicomplexan parasites. This plastid hosts several important biosynthetic pathways, which makes it an attractive organelle for identifying new potential drug targets. We thus addressed TgPL2 function by generating a conditional knockdown mutant and demonstrated it has an essential contribution for maintaining the integrity of the plastid. In absence of TgPL2, the organelle is rapidly lost and remaining apicoplasts appear enlarged, with an abnormal accumulation of membranous structures, suggesting a defect in lipids homeostasis. More precisely, analyses of lipid content upon TgPL2 depletion suggest this protein is important for maintaining levels of apicoplast‐generated fatty acids, and also regulating phosphatidylcholine and lysophosphatidylcholine levels in the parasite.
Alteration in important quality traits and antioxidant activities in Brassica oleracea with Ogura cybrid cytoplasm
Authors: Dey Shyam S. , Bhatia Reeta , Parkash Chander , Sharma Saharsh , Dabral Manish , Mishra Vibha , Bhardwaj Ila , Sharma Komal , Sharma Vinod Kumar , Kumar Raj 
Published: April 2017

AbstractIn vegetable brassicas, cytoplasmic male sterility (CMS) system is the most preferred mechanism for hybrid seed production and Ogura cybrid cytoplasm is the only source used widely. Effects of the alien cybrid cytoplasm on important quality traits need to be understood for their effective use in breeding programme. In analysing 38 Ogura cybrid cytoplasm‐based cauliflower CMS lines, it was revealed that introgression of Ogura cytoplasm resulted in significant alteration in important quality traits. Cupric reducing antioxidant activity and ferric reducing ability of plasma values were increased up to 5–10 times in different genotypes. Among 38 analysed CMS lines, concentration of plant pigments such as anthocyanin, total chlorophylls and ascorbic acid was reduced in 21, 17 and 32 genotypes, respectively. However, the concentration of total carotenoids and β‐carotene was elevated in most of the CMS lines and total carotenoid was increased up to 20 times in the CMS line, Ogu13‐85‐2A. The results indicate the role of nuclear–cytoplasmic interaction and mitochondrial genome in determining concentration of different quality traits.
Critical discourse analysis of social justice in nursing's foundational documents
Authors: Valderama‐Wallace Claire P. 
Published: April 2017

AbstractObjectiveSocial inequities threaten the health of the global population. A superficial acknowledgement of social justice by nursing's foundational documents may limit the degree to which nurses view injustice as relevant to nursing practice and education. The purpose was to examine conceptualizations of social justice and connections to broader contexts in the most recent editions.DesignCritical discourse analysis examines and uncovers dynamics related to power, language, and inequality within the American Nurses Association's Code of Ethics, Scope and Standards of Practice, and Social Policy Statement.ResultsThis analysis found ongoing inconsistencies in conceptualizations of social justice. Although the Code of Ethics integrates concepts related to social justice far more than the other two, tension between professionalism and social change emerges. The discourse of professionalism renders interrelated cultural, social, economic, historical, and political contexts nearly invisible.ConclusionGreater consistency would provide a clearer path for nurses to mobilize and engage in the courageous work necessary to address social injustice. These findings also call for an examination of how nurses can critique and use the power and privilege of professionalism to amplify the connection between social institutions and health equity in nursing education, practice, and policy development.
Origins and evolution of innate lymphoid cells: Wardens of barrier immunity
Authors: Neill D. R. , Flynn R. J. 
Published: April 2017

SummaryThe identification, in the late 2000s, of innate lymphoid cells (ILCs) as a new class of non‐B, non‐T lymphocytes has led to global efforts to understand their functions, plasticity and evolutionary origins and to define their place within the leucocyte family. Although this work has uncovered striking similarities in the developmental cues, lineage‐specific transcription factors and functional capacities of innate and adaptive lymphocytes, it has become clear that ILCs play a unique and defining role as stewards of barrier defence and that this sets them apart from their adaptive cousins. This review will explore how the dynamic environment of barrier surfaces has shaped ILC evolution and functionality. We highlight the critical importance of the microbiome and the unique role of ILCs as environmental sensors. We reflect on how these factors may have influenced the development of ILC2s and barrier immunity in the context of exposure to helminth parasites that have been driving forces of our evolution throughout human history. Finally, we argue that the plasticity of ILC function reflects their role as first responders to environmental change.
Interaction of an antecedent fluvial system with early normal fault growth: Implications for syn‐rift stratigraphy, western Corinth rift (Greece)
Authors: Hemelsdaël Romain , Ford Mary , Malartre Fabrice , Gawthorpe Rob 
Published: April 2017

AbstractContinental ‘overfilled’ conditions during rift initiation are conventionally explained as due to low creation of accommodation compared with sediment supply. Alternatively, sediment supply can be relatively high from the onset of rifting due to an antecedent drainage system. The alluvial Lower Group of the western Plio–Pleistocene Corinth rift is used to investigate the interaction of fluvial sedimentation with early rifting. This rift was obliquely superimposed on the Hellenide mountain belt from which it inherited a significant palaeorelief. Detailed sedimentary logging and mapping of the well‐exposed syn‐rift succession document the facies distributions, palaeocurrents and stratigraphic architecture. Magnetostratigraphy and biostratigraphy are used to date and correlate the alluvial succession across and between fault blocks. From 3·2 to 1·8 Ma, a transverse low sinuosity braided river system flowed north/north‐east to east across east–west‐striking active fault blocks (4 to 7 km in width). Deposits evolved downstream from coarse alluvial conglomerates to fine‐grained lacustrine deposits over 15 to 30 km. The length scale of facies belts is much greater than, and thus not directly controlled by, the width of the fault blocks. At its termination, the distributive river system built small, stacked deltas into a shallow lake margin. The presence of a major antecedent drainage system is supported by: (i) a single major sediment entry point; (ii) persistence of a main channel belt axis; (iii) downstream fining at the scale of the rift basin. The zones of maximum subsidence on individual faults are aligned with the persistent fluvial axis, suggesting that sediment supply influenced normal fault growth. Instead of low accommodation rate during the early rift phase, this study proposes that facies progradation can be controlled by continuous and high sediment supply from antecedent rivers.