bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teologia, Direitos Humanos e Pensamento Decolonial
Authors: Cunha Carlos Alberto Motta 
Published: September 2017

<p><span style="font-family: Times New Roman; font-size: medium;">No livro </span><em><span style="font-family: Times New Roman; font-size: medium;">Se Deus fosse um ativista dos direitos humanos</span></em><span style="font-family: Times New Roman; font-size: medium;">, Boaventura de Sousa Santos defende a ideia de que o diálogo entre os direitos humanos e as teologias progressistas é uma boa possibilidade para o desenvolvimento de práticas interculturais e emancipadoras (2014, p.113). Como a teologia pode contribuir para a reconstrução da humanidade dos direitos humanos? A contemporaneidade com toda a sua complexidade reclama a construção de uma teologia consciente da pluralidade cultural e religiosa capaz de abraçar dentro de seu horizonte as experiências sócio-religiosas do conjunto da humanidade. A tarefa de decolonizar a teologia, e/ou de recriar seu conteúdo, não implica apenas uma novidade no objeto, mas exige também uma novidade no sujeito, ou seja, faz-se necessário um novo tipo de teólogo, com um novo tipo de consciência e postura diante da atualidade. Na busca por respostas aproximativas, este artigo faz apontamentos sobre o processo necessário de decolonização da teologia cristã almejando uma intelecção da fé que seja pública e engajada nas causas do mundo e do humano.</span></p>
A pneumatologia como fundamento teológico do diálogo inter-religioso para as Assembleias de Deus no Brasil
Authors: Lima Adriano Sousa 
Published: September 2017

<p> As Assembleias de Deus representam o pentecostalismo clássico, que teve início no Brasil, no ano de 1911, tendo como base a experiência do Espírito e de seus dons. Hoje, essas igrejas somam mais de 15 milhões de membros e a doutrina sobre o Espírito Santo continua sendo uma das suas bases mais importantes. O Brasil de hoje, diferente de 1911, é um país pluralizado na sua cultura e na manifestação religiosa. Diante desse contexto, o diálogo entre as religiões é um imperativo fundamental no Brasil. O Espírito Santo, promove a unidade, o diálogo, a convivência e a amizade entre os diferentes. É o Espírito que sopra vida e comunhão em lugares diversos. Por essa razão, o Espírito pode ser base, para os assembleianos, para um diálogo entre as diferentes religiões. Assim, a pesquisa tem como objetivo fundamentar, em função das Assembleias de Deus, o diálogo inter-religioso a partir da doutrina do Espírito Santo. Para isso, buscará extrair da pneumatologia elementos que contribuam para repensar a teologia pentecostal das assembleias de Deus, a fim de introduzi-las no diálogo inter-religioso. A partir da metodologia de análise bibliográfica, ficarão claras as conclusões seguintes: o Espírito Santo está presente em todo ser humano; o cuidado com o meio ambiente, a busca pela justiça e pela paz, são aspectos pneumatológicos comuns a todos os cristãos e pertinentes a diferentes tradições religiosas. O Espírito promove amizade e comunhão entre os seres humanos; em termos concretos, o resultado é a convivência harmoniosa entre pessoas de diferentes tradições religiosas. Assim, é possível concluir a fecundidade da pneumatologia como fundamento para o diálogo inter-religioso nas Assembleias de Deus.</p>
Turbulent Entrainment Into Volcanic Plumes: New Constraints From Laboratory Experiments on Buoyant Jets Rising in a Stratified Crossflow
Authors: Aubry T. J. , Carazzo G. , Jellinek A. M. 
Published: October 2017

AbstractPredictions for the heights and downwind trajectories of volcanic plumes using integral models are critical for the assessment of risks and climate impacts of explosive eruptions but are strongly influenced by parameterizations for turbulent entrainment. We compare four popular parameterizations using small scale laboratory experiments spanning the large range of dynamical regimes in which volcanic eruptions occur. We reduce uncertainties on the wind entrainment coefficient β which quantifies the contribution of wind‐driven radial velocity shear to entrainment and is a major source of uncertainty for predicting plume height. We show that models better predict plume trajectories if (i) β is constant or increases with the plume buoyancy to momentum flux ratio and (ii) the superposition of the axial and radial velocity shear contributions to the turbulent entrainment is quadratic rather than linear. Our results have important implications for predicting the heights and likelihood of collapse of volcanic columns.
Dissolved Organic Matter Compositional Change and Biolability During Two Storm Runoff Events in a Small Agricultural Watershed
Authors: Eckard Robert S. , Pellerin Brian A. , Bergamaschi Brian A. , Bachand Philip A. M. , Bachand Sandra M. , Spencer Robert G. M. , Hernes Peter J. 
Published: September 2017

AbstractAgricultural watersheds are globally pervasive, supporting fundamentally different organic matter source, composition, and concentration profiles in comparison to natural systems. Similar to natural systems, agricultural storm runoff exports large amounts of organic carbon from agricultural land into waterways. But intense management of upper soil layers, waterway channelization, wetland and riparian habitat removal, and postharvest vegetation removal promise to uniquely drive organic matter release to waterways. During a winter first flush and a subsequent storm event, this study investigated the influence of a small agricultural watershed on dissolved organic matter (DOM) source, composition, and biolability. Storm water discharge released strongly terrestrial yet biolabile (23 to 32%) dissolved organic carbon (DOC). Following a 21 day bioassay, a parallel factor analysis identified an 80% reduction in a protein‐like (phenylpropyl) component (C2) that was previously correlated to lignin phenol concentration, and a 10% reduction in a humic‐like, terrestrially sourced component (C4). Storm‐driven releases tripled DOC concentration (from 2.8 to 8.7 mg L−1) during the first flush event in comparison to base flow and were terrestrially sourced, with an eightfold increase in vascular plant derived lignin phenols (23.0 to 185 μg L−1). As inferred from system hydrology, lignin composition, and nitrate as a groundwater tracer, an initial pulse of dilute water from the upstream watershed caused a counterclockwise DOC hysteresis loop. DOC concentrations peaked after 3.5 days, with the delay between peak discharge and peak DOC attributed to storm water hydrology and a period of initial water repellency of agricultural soils, which delayed DOM leaching.
Ruthenium‐Catalyzed para‐Selective C−H Alkylation of Aniline Derivatives
Authors: Leitch Jamie A. , McMullin Claire L. , Paterson Andrew J. , Mahon Mary F. , Bhonoah Yunas , Frost Christopher G. 
Published: October 2017

AbstractThe para‐selective C−H alkylation of aniline derivatives furnished with a pyrimidine auxiliary is herein reported. This reaction is proposed to take place via an N−H‐activated cyclometalate formed in situ. Experimental and DFT mechanistic studies elucidate a dual role of the ruthenium catalyst. Here the ruthenium catalyst can undergo cyclometalation by N−H metalation (as opposed to C−H metalation in meta‐selective processes) and form a redox active ruthenium species, to enable site‐selective radical addition at the para position.
Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo
Authors: Martínez‐Sáez Nuria , Sun Shuang , Oldrini Davide , Sormanni Pietro , Boutureira Omar , Carboni Filippo , Compañón Ismael , Deery Michael J. , Vendruscolo Michele , Corzana Francisco , Adamo Roberto , Bernardes Gonçalo J. L. 
Published: October 2017

AbstractA four‐membered oxygen ring (oxetane) can be readily grafted into native peptides and proteins through site‐selective bis‐alkylation of cysteine residues present as disulfides under mild and biocompatible conditions. The selective installation of the oxetane graft enhances stability and activity, as demonstrated for a range of biologically relevant cyclic peptides, including somatostatin, proteins, and antibodies, such as a Fab arm of the antibody Herceptin and a designed antibody DesAb‐Aβ against the human Amyloid‐β peptide. Oxetane grafting of the genetically detoxified diphtheria toxin CRM197 improves significantly the immunogenicity of this protein in mice, which illustrates the general utility of this strategy to modulate the stability and biological activity of therapeutic proteins containing disulfides in their structures.
Guest‐Switchable Multi‐Step Spin Transitions in an Amine‐Functionalized Metal–Organic Framework
Authors: Liu Wei , Peng Yuan‐Yuan , Wu Si‐Guo , Chen Yan‐Cong , Hoque Md. Najbul , Ni Zhao‐Ping , Chen Xiao‐Ming , Tong Ming‐Liang 
Published: October 2017

AbstractMaterials with hysteretic multi‐step spin‐crossover (SCO) have potential application in high‐order data storage. Here, an unprecedented hysteretic four‐step SCO behavior with the sequence of LS↔HS0.25LS0.75↔HS0.5LS0.5↔ HS0.75LS0.25↔HS is found in a three‐dimensional (3D) Hofmann‐type metal–organic framework (MOF), which is evidenced by magnetic, differential scanning calorimetry, and crystal data. Further experiments involving guest exchange leads to the first reversible modulation of four‐, two‐, and one‐stepped SCO behaviors, which provides a new strategy for developing multi‐step SCO materials.
Tetrazole‐Based Probes for Integrated Phenotypic Screening, Affinity‐Based Proteome Profiling, and Sensitive Detection of a Cancer Biomarker
Authors: Cheng Ke , Lee Jun‐Seok , Hao Piliang , Yao Shao Q. , Ding Ke , Li Zhengqiu 
Published: October 2017

AbstractTarget‐identification phenotypic screening has been a powerful approach in drug discovery; however, it is hindered by difficulties in identifying the underlying cellular targets. To address this challenge, we have combined phenotypic screening of a fully functionalized small‐molecule library with competitive affinity‐based proteome profiling to map and functionally characterize the targets of screening hits. Using this approach, we identified ANXA2, PDIA3/4, FLAD1, and NOS2 as primary cellular targets of two bioactive molecules that inhibit cancer cell proliferation. We further demonstrated that a panel of probes can label and/or image annexin A2 (a cancer biomarker) from different cancer cell lines, thus providing opportunities for potential cancer diagnosis and therapy.
Sprout‐like Growth of Mesoporous Mo2C/NC Nanonetworks as Efficient Electrocatalysts for Hydrogen Evolution
Authors: Fan Meihong , Zheng Yuenan , Li Ang , Ma Yali , Huo Qisheng , Qiao Zhen‐An , Dai Sheng 
Published: October 2017

AbstractOwing to their high surface areas, porous networks, nanosized walls, and unique electronic structure, mesoporous metal carbides with tailored nanoarchitectures are of particular interest for their prominent potential applications in various fields, including energy storage, fuel cells, and catalysis. Herein, we report a sprout‐like growth strategy for the preparation of a mesoporous β‐Mo2C nanonetwork embedded in a nitrogen‐rich carbon matrix. The nanoarchitecture can be tailored from a mesoporous Mo2C nanonetwork film into Mo2C nanoparticles embedded into the carbon layer. The as‐prepared β‐Mo2C material was demonstrated to drive a current density of 10 mA cm−2 at a low overpotential of 140 mV for the hydrogen evolution reaction (HER) in acidic conditions and to remain stable for at least 120 h. The excellent electrocatalytic performance may be from (1) mesoporous Mo2C frameworks offering numerous accessible active sites; (2) a carbon layer that protects the Mo2C from accumulation and favors electron transportation; and (3) shortened diffusion paths and ultrafine crystallinity that benefit its catalytic performance.
Statistical inference using generalized linear mixed models under informative cluster sampling
Authors: Kim Jae Kwang , Park Seunghwan , Lee Youngjo 
Published: September 2017

AbstractWhen a sample is obtained from a two‐stage cluster sampling scheme with unequal selection probabilities the sample distribution can differ from that of the population and the sampling design can be informative. In this case making valid inference under generalized linear mixed models can be quite challenging. We propose a novel approach for parameter estimation using an EM algorithm based on the approximate predictive distribution of the random effect. In the approximate predictive distribution instead of using the intractable sample likelihood function we use a normal approximation of the sampling distribution of the profile pseudo maximum likelihood estimator of the random effects in the level‐one model. Two limited simulation studies show that the proposed method using the normal approximation performs well for modest cluster sizes. The proposed method is applied to the real data arising from 2011 Private Education Expenditures Survey (PEES) in Korea. The Canadian Journal of Statistics 45: 479–497; 2017 © 2017 Statistical Society of Canada
Sugar‐Coated Nanobullet: Growth Inhibition of Cancer Cells Induced by Metformin‐Loaded Glyconanoparticles
Authors: Qian Ruo‐Can , Lv Jian , Li Hao‐Wen , Long Yi‐Tao 
Published: October 2017

AbstractMetformin, a widely used drug for treating type‐2 diabetes, has now been discovered to reduce cancer cell proliferation. However, further efforts are needed to design effective metformin delivery vehicles, instead of bare metformin. Herein we report a highly efficient transport nanostructure based on core–shell glyconanoparticles (GNPs), with gold as the core and dextran as the shell interspersed with metformin molecules. The dextran shell facilitates the entry of GNPs into living cells, which allows the subsequent release of metformin. Using MCF‐7 breast cancer cells as an example, significant cell growth inhibition was observed after treatment of metformin‐containing GNPs (MGNPs). Compared with bare metformin or bare GNPs, MGNPs show a stronger capacity for cell growth inhibition with good biocompatibility. Furthermore, inactivation of mitochondria and activation of p53 protein are observed during MGNP treatment, which provides evidence for metformin‐induced cell apoptosis pathways. This work provides a new therapeutic tool for the treatment of cancer.
A Ferrocene–Tryptophan Conjugate: The Role of the Indolic Nitrogen in Supramolecular Assembly
Authors: Falcone Natashya , Basak Shibaji , Dong Bin , Syed Jebriel , Ferranco Annaleizle , Lough Alan , She Zhe , Kraatz Heinz‐Bernhard 
Published: October 2017

AbstractBio‐organometallic ferrocene‐containing amino acids and peptides have been reported to form gels and are interesting to study due to their structural properties and applications for biological purposes. In this study, a ferrocene‐dicarboxylic acid derivative of the dipeptide tryptophan–tryptophan was investigated. The indolic nitrogen in the amino acid tryptophan is important for biological functions due to its role in hydrogen bonding. Here, intermolecular interactions with the indolic nitrogen allow this conjugate to self‐assemble into a fibrous supramolecular structure that forms a stable gel. Rheological analysis demonstrates the self‐healing nature of this gel. Interestingly, X‐ray analysis of this ferrocene–peptide conjugate reveals close contacts involving tryptophan, in particular the indole NH group in interactions with an adjacent neighboring molecule.
Electrocatalytic Metal–Organic Frameworks for Energy Applications
Authors: Downes Courtney A. , Marinescu Smaranda C. 
Published: October 2017

AbstractWith the global energy demand expected to increase drastically over the next several decades, the development of a sustainable energy system to meet this increase is paramount. Renewable energy sources can be coupled with electrochemical conversion processes to store energy in chemical bonds. To promote these difficult transformations, electrocatalysts that operate at high conversion rates and efficiency are required. Metal–organic frameworks (MOFs) have emerged as a promising class of materials; however, the insulating nature of MOFs has limited their application as electrocatalysts. The recent development of conductive MOFs has led to several electrocatalytic MOFs that display activity comparable to that of the best‐performing heterogeneous catalysts. Although many electrocatalytic MOFs exhibit low activity and stability, the few successful examples highlight the possibility of MOF electrocatalysts as replacements for noble‐metal‐based catalysts in commercial energy‐converting devices. We review herein the use of pristine MOFs as electrocatalysts to facilitate important energy‐related reactions.
Prozac in the water: Chronic fluoxetine exposure and predation risk interact to shape behaviors in an estuarine crab
Authors: Peters Joseph R. , Granek Elise F. , de Rivera Catherine E. , Rollins Matthew 
Published: September 2017

AbstractPredators exert considerable top‐down pressure on ecosystems by directly consuming prey or indirectly influencing their foraging behaviors and habitat use. Prey is, therefore, forced to balance predation risk with resource reward. A growing list of anthropogenic stressors such as rising temperatures and ocean acidification has been shown to influence prey risk behaviors and subsequently alter important ecosystem processes. Yet, limited attention has been paid to the effects of chronic pharmaceutical exposure on risk behavior or as an ecological stressor, despite widespread detection and persistence of these contaminants in aquatic environments. In the laboratory, we simulated estuarine conditions of the shore crab, Hemigrapsus oregonensis, and investigated whether chronic exposure (60 days) to field‐detected concentrations (0, 3, and 30 ng/L) of the antidepressant fluoxetine affected diurnal and nocturnal risk behaviors in the presence of a predator, Cancer productus. We found that exposure to fluoxetine influenced both diurnal and nocturnal prey risk behaviors by increasing foraging and locomotor activity in the presence of predators, particularly during the day when these crabs normally stay hidden. Crabs exposed to fluoxetine were also more aggressive, with a higher frequency of agonistic interactions and increased mortality due to conflicts with conspecifics. These results suggest that exposure to field‐detected concentrations of fluoxetine may alter the trade‐off between resource acquisition and predation risk among crabs in estuaries. This fills an important data gap, highlighting how intra‐ and interspecific behaviors are altered by exposure to field concentrations of pharmaceuticals; such data more explicitly identify potential ecological impacts of emerging contaminants on aquatic ecosystems and can aid water quality management.
Global population structure and adaptive evolution of aflatoxin‐producing fungi
Authors: Moore Geromy G. , Olarte Rodrigo A. , Horn Bruce W. , Elliott Jacalyn L. , Singh Rakhi , O'Neal Carolyn J. , Carbone Ignazio 
Published: September 2017

AbstractAflatoxins produced by several species inAspergillussectionFlaviare a significant problem in agriculture and a continuous threat to human health. To provide insights into the biology and global population structure of species in sectionFlavi, a total of 1,304 isolates were sampled across six species (A. flavus, A. parasiticus, A. nomius, A. caelatus, A. tamarii,andA. alliaceus) from single fields in major peanut‐growing regions in Georgia (USA), Australia, Argentina, India, and Benin (Africa). We inferred maximum‐likelihood phylogenies for six loci, both combined and separately, including two aflatoxin cluster regions (aflM/alfNandaflW/aflX) and four noncluster regions (amdS, trpC, mfsandMAT), to examine population structure and history. We also employed principal component and STRUCTURE analysis to identify genetic clusters and their associations with six different categories (geography, species, precipitation, temperature, aflatoxin chemotype profile, and mating type). Overall, seven distinct genetic clusters were inferred, some of which were more strongly structured by G chemotype diversity than geography. Populations ofA. flavusS in Benin were genetically distinct from all other sectionFlavispecies for the loci examined, which suggests genetic isolation. Evidence of trans‐speciation within two noncluster regions, wherebyA. flavusSBGstrains from Australia share haplotypes with eitherA. flavusorA. parasiticus, was observed. Finally, while clay soil and precipitation may influence species richness inAspergillussectionFlavi, other region‐specific environmental and genetic parameters must also be considered.
The Science Behind the Academy for Eating Disorders' Nine Truths About Eating Disorders
Authors: Schaumberg Katherine , Welch Elisabeth , Breithaupt Lauren , Hübel Christopher , Baker Jessica H. , Munn‐Chernoff Melissa A. , Yilmaz Zeynep , Ehrlich Stefan , Mustelin Linda , Ghaderi Ata , Hardaway Andrew J. , Bulik‐Sullivan Emily C. , Hedman Anna M. , Jangmo Andreas , Nilsson Ida A.K. , Wiklund Camilla , Yao Shuyang , Seidel Maria , Bulik Cynthia M. 
Published: October 2017

AbstractObjectiveIn 2015, the Academy for Eating Disorders collaborated with international patient, advocacy, and parent organizations to craft the ‘Nine Truths About Eating Disorders’. This document has been translated into over 30 languages and has been distributed globally to replace outdated and erroneous stereotypes about eating disorders with factual information. In this paper, we review the state of the science supporting the ‘Nine Truths’.MethodsThe literature supporting each of the ‘Nine Truths’ was reviewed, summarized and richly annotated.ResultsMost of the ‘Nine Truths’ arise from well‐established foundations in the scientific literature. Additional evidence is required to further substantiate some of the assertions in the document. Future investigations are needed in all areas to deepen our understanding of eating disorders, their causes and their treatments.ConclusionsThe ‘Nine Truths About Eating Disorders’ is a guiding document to accelerate global dissemination of accurate and evidence‐informed information about eating disorders. Copyright © 2017 John Wiley & Sons, Ltd and Eating Disorders Association.
Predictors of survival after total laryngectomy for recurrent/persistent laryngeal squamous cell carcinoma
Authors: Birkeland Andrew C. , Beesley Lauren , Bellile Emily , Rosko Andrew J. , Hoesli Rebecca , Chinn Steven B. , Shuman Andrew G. , Prince Mark E. , Wolf Gregory T. , Bradford Carol R. , Brenner J. Chad , Spector Matthew E. 
Published: September 2017

AbstractBackgroundTotal laryngectomy remains the treatment of choice for recurrent/persistent laryngeal squamous cell carcinoma (SCC) after radiotherapy (RT) or chemoradiotherapy (CRT). However, despite attempts at aggressive surgical salvage, survival in this cohort remains suboptimal.MethodsA prospectively maintained single‐institution database was queried for patients undergoing total laryngectomy for recurrent/persistent laryngeal SCC after initial RT/CRT between 1998 and 2015(n = 244). Demographic, clinical, and survival data were abstracted. The Kaplan‐Meier survival curves and hazard ratios (HRs) were calculated.ResultsFive‐year overall survival (OS) was 49%. Five‐year disease‐free survival (DFS) was 58%. Independent predictors of OS included severe comorbidity (Adult Comorbidity Evaluation‐27 [ACE‐27] scale; HR 3.76; 95% confidence interval [CI] 1.56‐9.06), and positive recurrent clinical nodes (HR 2.91; 95% CI 1.74‐4.88).ConclusionSevere comorbidity status is the strongest predictor of OS, suggesting that increased attention to mitigating competing risks to health is critical. These data may inform a risk prediction model to allow for focused shared decision making, preoperative health optimization, and patient selection for adjuvant therapies.