bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow cytometric detection of endothelial progenitor cells (EPC) in acute coronary syndrome
Authors: Falay Mesude , Aktaş Server 
Published: January 2017

Abstract

Aim
The aim of the present study is to establish a moAb combination and a study procedure for the accurate determination of circulating EPC using multicolor flow cytometry, as well as to find out whether there is a relation between disease severity and EPC count by comparing the circulating EPC count between the subgroups of patients presented with acute coronary syndrome.

Materials and methods
Absolute circulating EPC count was identified in 40 healthy subjects and acute coronary syndrome patients using multicolor flow cytometry with a single-tube panel consisting of CD45, CD31, CD34, CD309 and syto 16 monoclonal antibodies.

Results
Circulating EPC count was 11.33 (7.89–15.25) cells/μL in healthy control group and 4.80 (0.70–10.85) cells/μL in acute coronary syndrome patients.

Conclusion
In the present study, which investigated whether there is a difference between EPC counts of STEMI and USAP patients that have presented with ACS, EPC count was lower in both disease groups as compared to healthy controls. First the method must be standardized and then harmonization studies are required in order to use this method as a prognostic factor in cardiovascular diseases.
Competition between intermolecular hydrogen bonding and stacking in the crystals of 4-Hydroxy-N-(pyridin-2-yl)-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides
Authors: Shishkina Svitlana V. , Ukrainets Igor V. , Petrushova Lidiya A. 
Published: January 2017

Abstract
The traditional crystal packing study based on the analysis of geometrical characteristics of intermolecular interactions is found to be not informative enough. The application of quantum-chemical calculations for the evaluation of pairwise interaction energies between molecules allows to get much more information about supramolecular architecture. The staking interactions between π-systems of neighboring molecules form the building unit of the crystal packing in the absence of any strong interactions as well as in the presence of the N–H…O classical hydrogen bond. Unexpectedly the hydrogen bonds play the secondary role in the crystal packing formation as compared to stacking. Analysis of the total interaction energy of the basic molecule with all the molecules of its first coordination sphere and the pairwise interaction energies allows to evaluate the extent of crystal isotropy from point of view of interaction energies.
Bioenergetics of lactate vs. acetate outside TCA enhanced the hydrogen evolution levels in two newly isolated strains of the photosynthetic bacterium Rhodopseudomonas
Authors: Danial Amal W. , Abdel Wahab Ahmed M. , Arafat Houssam H. , Abdel-Basset Refat 
Published: January 2017

Abstract
Two local hydrogen-evolving strains of purple nonsulfur bacteria have been isolated, characterized, and identified as Rhodopseudomonas sp. TUT (strains Rh1 and Rh2). Lactate followed by succinate and malate supported the highest amounts of H2 production, growth (O.D.660nm, proteins and bacteriochlorphyll contents), nitrogenase activity, and uptake hydrogenase; the least of which was acetate. Alginate-immobilized cells evolved higher hydrogen amounts than free cell counterparts. Rh1 was more productive than Rh2 at all circumstances. Lactate-dependent hydrogen evolution was more than twice that of acetate, due to ATP productivity (2/–1, respectively), which is limiting to the nitrogenase activity. The preference of lactate over other acids indicates the feasibility of using these two strains in hydrogen production from dairy wastewater.
Importance of Horizontally Loaded Movements to Sports Performance
Authors: Zweifel Michael 
Published: January 2017

ABSTRACT
THE USE OF VERTICALLY LOADED EXERCISES, SUCH AS THE BACK SQUAT, DEADLIFT, AND OLYMPIC-STYLE LIFTS, ARE COMMONLY PRESCRIBED BY STRENGTH AND CONDITIONING PROFESSIONALS TO ENHANCE THE PHYSICAL QUALITIES OF ATHLETES. THESE METHODS HAVE BEEN SUPPORTED AS EFFECTIVE MEANS, MAINLY FOR NOVICE SUBJECTS, BUT THEIR EFFECTIVENESS AND TRANSFER HAS BEEN QUESTIONED IN MORE ADVANCED ATHLETES AND IN TRANSFER TO SPECIFIC PHYSICAL QUALITIES. THE EFFECTIVENESS OF VERTICALLY LOADED EXERCISE TO ENHANCE SPRINTING SPEED AND CHANGE OF DIRECTION (COD) SPEED IS EQUIVOCAL IN ADVANCED ATHLETES, AND THE USE OF HORIZONTALLY LOADED MOVEMENT MAY HAVE BETTER TRANSFER FOR SPRINTING SPEED AND COD SPEED.
Increasing Strength and Power With Gada, Indian Clubs, Bulgarian Bags, and Other Tools of Concentric Strength
Authors: Schoenfeld Melody L. 
Published: January 2017

ABSTRACT
ALTHOUGH IMPLEMENTS SUCH AS MACES AND CLUBS HAVE BEEN USED EXTENSIVELY THROUGHOUT THE HISTORY OF PHYSICAL CULTURE, THERE IS CURRENTLY NO RESEARCH ON THE BENEFITS OF THESE TOOLS. THIS ARTICLE CONNECTS CURRENT RESEARCH IN EXERCISES THAT HAVE BEEN USED SUCCESSFULLY TO REHABILITATE AND STRENGTHEN THE SHOULDER AND THE USE OF THE GADA, LIGHT CLUB, HEAVY CLUB, AND BULGARIAN BAG. BASIC MOVEMENTS USING THE GADA, LIGHT CLUB, HEAVY CLUB, AND BULGARIAN BAG WILL ALSO BE DEMONSTRATED.
The Glasgow ‘Deep End’ Links Worker Study Protocol: A Quasi-Experimental Evaluation of a Social Prescribing Intervention for Patients with Complex Needs in Areas of High Socioeconomic Deprivation
Authors: Mercer Stewart W. , Fitzpatrick Bridie , Grant Lesley , Chng Nai Rui , O'Donnell Catherine A. , Mackenzie Mhairi , McConnachie Alex , Bakhshi Andisheh , Wyke Sally 
Published: January 2017

Background ‘Social prescribing’ can be used to link patients with complex needs to local (non-medical) community resources. The ‘Deep End’ Links Worker Programme is being tested in general practices serving deprived populations in Glasgow, Scotland. Objectives To assess the implementation and impact of the intervention at patient and practice levels. Methods Study design: Quasi-experimental outcome evaluation with embedded theory-driven process evaluation in 15 practices randomized to receive the intervention or not. Complex intervention: Comprising a practice development fund, a practice-based community links practitioner (CLP), and management support. It aims to link patients to local community organizations and enhance practices’ social prescribing capacity. Study population: For intervention practices, staff and adult patients involved in referral to a CLP, and a sample of community organization staff. For comparison practices, all staff and a random sample of adult patients. Sample size: 286 intervention and 484 comparator patients. Outcomes: Primary patient outcome is health-related quality of life (EQ-5D-5L). Secondary patient outcomes include capacity, depression/anxiety, self-esteem, and healthcare utilization. Practice outcome measures include team climate, job satisfaction, morale, and burnout. Outcomes measured at baseline and 9 months. Processes: Barriers and facilitators to implementation of the programme and possible mechanisms through which outcomes are achieved. Analysis plan: For outcome, intention-to-treat analysis with differences between groups tested using mixed-effects regression models. For process, case-study approach with thematic analysis. Discussion This evaluation will provide new evidence about the implementation and impact of social prescribing by general practices serving patients with complex needs living in areas of high deprivation.
El tratamiento quirúrgico de ciertas formas de alteración del ciclo menstrual
Authors: Almenara Valdéz Guillermo 
Published: January 2017

Las primeras comunicaciones que consignan casos de hiperplasias endometriales, con formación ocasional de pólipos uterinos y acompañados de metrorragias, fueron las publicadas por Robert en 1846, Robinson en 1848 y Nelaton en 1853. Recamier preconizó, por entonces, el raspado uterino, como tratamiento de la afección.
Standarización de la Unidad Sapo en el Dosaje de Gonadotrofinas Coriónicas
Authors: Roe Gómez Carlos 
Published: January 2017

El dosaje de Gonadotrofinas Coriónicas, siguiendo la técnica de Galli Mainini, es una sencilla y rápida prueba de laboratorio, cuya importancia clínica está demás recalcar. Para poder realizar el dosoie de Gonadotrofinas Coriónicas, siguiendo la técnica citada, es necesario conocer la dosis mínima capaz de producir respuesta biológica positiva, en el sapo macho. 1 Los valores dados a esta cifra, varían según los diferentes autores, y esta variación se debe: a)	Al bajo número de animales empleados. b)	A las diversas técnicas empleadas. c)	A los diferentes patrones usados. d)	A la falta de un valor umbral. Hemos tratado de eliminar estas posibilidades de error, para determinar en el Sapo Macho (Bufo Spinolosus Limensis) de Lima y alrededores, la dosis mínima capaz de producir respuesta biológica positiva, empleando 420 animales, usando como patrones todos los productos comerciales de Gonadotrofinas Coriónicas que hay en plaza y siguiendo exactamente la técnica de Galli Mainini. Analizando los resultados obtenidos con criterio estadístico, aplicando los conceptos desarrollados por J. H. Gaddum y sugerimos definir la dosis mínima como aquella capaz de producir respuesta biológica positiva en el 50% de la población experimental. Sugerimos tomar este dato como valor umbral, definiendo la Unidad Sapo como: "la dosis mínima capaz de producir respuesta biológica positiva en el 50% de la población experimental". Hemos encontrado que la Unidad Sapo (U.S.), en el Bufo Spinolosus Limensis de Lima y alrededores, equivale a: 31 Unidades Internacionales (U. I.) para las hormonas Gonadotróficas Coriónicas de origen humano y 73 Unidades Internacionales (U. I.) para las hormonas Gonadotróficas Coríónicas de origen equino. Desarrollamos un método gráfico-matemático sencillo y práctico que permite hallar rápidamente el valor de la Unidad Sapo (U.S.) y que a la vez hace posible determinar el origen y equivalencia de cualquier hormona Gonadotrófica Coriónica. Sugerimos que se emplee este método para futuras determinaciones del valor de la Unidad Sapo (U.S.), empleando una preparación standard de Gonadotrofinas Coriónicas tal como la recomendada por el Comité de la Liga de las Naciones.
El efecto Hipoprotrombinemico de dos anticuagulantes de la serie Cumarinica en nuestro medio
Authors: Forno Carlos , Vidurrizaga Carlos M. , Figallo Manuel 
Published: January 2017

Desde la introducción de los anticoagulantes cumarínicos en la práctica clínica en 1941 (1,2), complemento final a los trabajos experimentales de Karl Paul Link y su grupo (3,4), su uso se ha difundido extraordinariamente. En efecto; la protección que ofrecen estas drogas como antagonistas de los procesos tromboembólicos les confiere valo singular en todos los casos, cuyo denominador común está dado por aquellos. Sin embargo, el control riguroso requerido para lograr una correcta dosificación que asegure simultáneamente un efecto antitrombótico óptimo y seguridad contra la hemorragia, ha sido quizás uno de los factores para que, entre nosotros, su empleo sea muy restringido.
Las Trombocitopenias en Relación con la Inmuno – Hematología
Authors: Figallo Moreno Manuel Andrés 
Published: January 2017

Desde 1871 Bronn y Krause (4) observaron una relación entre el síndrome purpúrico y la presencia de trombocitopenia en la sangre periférica. En la Púrpura Trombocitopénica Idiopática indudablemente que uno de los hechos más característicos es el síndrome purpúrico y la trombocitopenia en sangre periférica. Cualquier teoría que trate de explicar la patogenia de esta enfermedad tiene que dar explicación lógica a tres aspectos fundamentales vistos en este proceso. 1)	Trombocitopenia en sangre periférica. 2)	Número aumentado o normal de megacariocitos en la médula ósea con sus cambios morfológicos característicos. 3) Efecto benefactor de la esplenectomía en la mayoría de los casos.
Vector – Electrocardiografía en casos probados de cardiografías congénitas
Authors: Eyzaguirre R. Guillermo A. 
Published: January 2017

1. a) Hemos presentado Vector y Electrocardiográficamente 35 casos de Cardiopatía s Congénitas todos los cuales han tenido comprobación quirúrgica. Ellos son: Comunicación Interauricular, 20 casos; Persistencia del Canal Atrioventricular, 6 casos; Estenosis Pulmonar, 5 casos y Tetralogía de Fallot, 4 casos. b)	Se comentan las modificaciones que sufren el E.c.cr. y s VCG en relación con la evaluación y evolución post-operatoria. 2. a) El E.c.g. en Comunicación Interauricular tipo Ostium Secundum no mostró hallazgos significativos fuera de la Hipertrofia ventricular derecha y el patrón de rsR' en precordial V1. b)	Se mostró la correlación del "crochetage" del QRS con su similar en el vectorcardiograma en los casos de defecto septal tipo Ostium Secundum. c)	Se describen los hallazgos electrocardiográficos de desviación de A QRS a la izquierda, bloqueo de primer grado y el patrón RSR' en la derivación precordial V1 en los casos de persistencia de Canal Atrio-ventricular común. d)	Se describe el s VCG, en los casos de Canal Atrio-Ventricular Común y se hace notar el valor del electro y vectorcardiograma como métodos no sólo para el diagnóstico de las Comunicaciones Interauriculares sino para: la diferenciación entre los tipos Ostium Secundum y Primum. 3. a) Se discute la desviación del eje eléctrico a la derecha, la orientación vectorial de s E QRS en la Hipertrofia ventricular derecha severa y la discordancia del s E T en la Estenosis Pulmonar. 4. a) Se describe el A QRS y A T típicos de Tetralogía de Fallot y en sus orientaciones tridimensionales. El complejo Rs en V1 con significado de "ventrículo derecho sistémico". b)	Se comenta la correlación hemodinámica-electrocardiográfica. c) Se describe el Vectorcardiograma en la Tetralogía de Fallot clásica como un predominio de fuerzas eléctricas dirigidas anterior e inferiormente y hacia la derecha. 5.	Se propone un esquema tridimensional sobre el que se puede montar los electros y vectorcardiogramas en tal forma que el estudiante pueda leer e interpretar las fuerzas electromotrices.
Financiamiento de los Servicios de Salud Conceptos Generales
Authors: Mendoza Pedro 
Published: January 2017

En este artículo buscaremos presentar conceptos generales relativos a las diversasa modalidades de financiamiento de los servicios de salud, en momentos en los que en el país, y a nivel mundial, se re-evalúan tales conceptos en busca de formas más equitativas y eficientes de asegurar que los servicios de salud lleguen a la población.
Clínica Médica del hospital "Dos de Mayo"
Authors: Gonzáles Olaechea Maximiliano 
Published: January 2017

Lección inaugural del curso de 1922. Clínica Médica del hospital "Dos de Mayo". por el Dr. Maximiliano Gonzáles Olaechea, Catedrático de Clínica Médica en la Facultad de Medicina, de la Academia Nacional de Medicina de Lima.
La Neuro-axitis en su forma coreo-etetósica
Authors: Gonzáles Olaechea Maximiliano 
Published: January 2017

Lección en la Clínica Médica del Hospital "Dos de Mayo", La Neuro-axitis en su forma coreo-etetósica por el Profesor Dr. Maximiliano Gonzáles Olaechea, Catedrático de Clínica Médica, de la Academia Nacional de Medicina de Lima.
The role of affect-driven impulsivity in gambling cognitions: A convenience-sample study with a Spanish version of the Gambling-Related Cognitions Scale
Authors: Del Prete Francesco , Steward Trevor , Navas Juan F. , Fernández-Aranda Fernando , Jiménez-Murcia Susana , Oei Tian P. S. , Perales José C. 
Published: January 2017

Background and aims
Abnormal cognitions are among the most salient domain-specific features of gambling disorder. The aims of this study were: (a) to examine and validate a Spanish version of the Gambling-Related Cognitions Scale (GRCS; Raylu & Oei, 2004) and (b) to examine associations between cognitive distortion levels, impulsivity, and gambling behavior.

Methods
This study first recruited a convenience sample of 500 adults who had gambled during the previous year. Participants were assessed using the Spanish version of GRCS (GRCS-S) questionnaire, the UPPS-P impulsivity questionnaire, measures of gambling behavior, and potentially relevant confounders. Robust confirmatory factor analysis methods on half the sample were used to select the best models from a hypothesis-driven set. The best solutions were validated on the other half, and the resulting factors were later correlated with impulsivity dimensions (in the whole n = 500 factor analysis sample) and clinically relevant gambling indices (in a separate convenience sample of 137 disordered and non-disordered gamblers; validity sample).

Results
This study supports the original five-factor model, suggests an alternative four-factor solution, and confirms the psychometric soundness of the GRCS-S. Importantly, cognitive distortions consistently correlated with affect- or motivation-driven aspects of impulsivity (urgency and sensation seeking), but not with cognitive impulsivity (lack of premeditation and lack of perseverance).

Discussion and conclusions
Our findings suggest that the GRCS-S is a valid and reliable instrument to identify gambling cognitions in Spanish samples. Our results expand upon previous research signaling specific associations between gambling-related distortions and affect-driven impulsivity in line with models of motivated reasoning.
Early and late outcomes of trans-abdominal pre-peritoneal and Lichtenstein repair for inguinal hernia, a comparative study
Authors: Latif Bahram Mahmoud Abdel 
Published: January 2017

Background: Surgical repair of inguinal hernia remains a common operation in general surgery. No consensus has been achieved on the best surgical technique of inguinal herniorrhaphy. Open repair has lower recurrence and complication rates. Laparoscopic approach has less postoperative pain, reduced recovery time, earlier return to activity and fewer wound complications but expose the patient to potential complications, mainly possibility of visceral injury. The aim was to compare early and late outcomes after TAPP and lichtenstein repair.Methods: Three hundreds patients with inguinal hernia were enrolled in this study, divided into two equal groups: Group I managed by trans-abdominal pre-peritoneal laparoscopic repair (TAPP) and Group II managed by open lichtenstein repair (LR).Results: The operative time was significantly lower in TAPP than LR (50±18.98 min and 75±24.54 min respectively). TAPP has a significant advantage to diagnose and repair contra-lateral inguinal hernia (11.5%) and to repair concomitant umbilical hernia (7.3%). No significant difference between both groups regarding intra-operative visceral injury, ileus, hospital stay or wound complications. TAPP significantly decreased post-operative pain and groin hypothesia, shorten the duration needed to return to activities (7±3 days and 16±5 days respectively). There was no significant difference between both groups regarding the recurrence (4.2% and 2% respectively).Conclusions: TAPP technique is an excellent approach for treatment of inguinal hernia in comparison to LR either unilateral or bilateral, primary or recurrent inguinal hernia with low morbidity and recurrence comparable to that of LR with advantages of less post-operative pain and early return to activities.
Relationship between initial fibrinogen level with coagulopathy and mortality in multiple trauma patients
Authors: Rudiman Reno , Sulistyanti Lyana , Usman Nurhayat 
Published: January 2017

Background: In trauma induced coagulopathy (TIC), low fibrinogen value is often found and plasma fibrinogen reached low value earlier than other parameters of coagulation factors. Initial fibrinogen value is strongly correlated to the injury severity score (ISS) and be an independent predictor of mortality. This study was expected to see the relationship between initial fibrinogen level with coagulopathy and mortality, so it can predict early coagulopathy and can prevent bleeding complications that lead to mortality. Methods: The study was conducted prospectively. The entire examination obtained from patients with multiple trauma. Fibrinogen levels and coagulopathy were taken from the blood laboratory tests in conjunction with other routine examination when patients were admitted to the ER of Hasan Sadikin General Hospital. Outcome parameters were the incidence of coagulopathy and mortality. Statistical analyses were performed to look at the significance of relationships.Results: Of the 25 patients with multiple trauma obtained a majority of 80% were male patients and with the highest incidence mechanism was head trauma as many as 16 people (64%). There were 8 patients (32%) experienced coagulopathy and mortality occurred in 7 patients (28%). Chi square analysis found a significant association between fibrinogen and coagulopathy (p = 0.043), while the association between initial fibrinogen with mortality was not significant (p = 0.341).Conclusions: Initial fibrinogen level is significantly associated with coagulopathy but it cannot predict mortality in patients with multiple trauma. Further study is needed in order to assess the benefit of these results on the management of multiple trauma patients.
Evaluation of medial meniscal injury and anterior cruciate ligament tear by MRI with arthroscopic correlation
Authors: Murmu Chiranjib , Tiwari Pushpakant , Agrawal Vijender Kumar 
Published: January 2017

Background: Apart from clinical examination multiple modalities (conventional radiography, MRI and arthroscopy) are currently used to evaluate knee injuries. This study is intended to compare the sensitivity and specificity of MRI in correlation of arthroscopy in diagnosing of knee injuries.Methods: This is a prospective study involving 51 patients with history of knee injuries who were admitted in the Department of Orthopaedics, Command Hospital, Kolkata, India from April 2013 to June 2014. MRI of the knee joint was done for all these patients either before or after admission. The patients were then subjected to diagnostic and therapeutic arthroscopy. Statistical analysis was used to calculate the sensitivity, specificity, positive predictive value and the negative predictive value, in order to assess the reliability of the MRI results.Results: The sensitivity and specificity of MRI with respect to arthroscopy in anterior cruciate ligament tear is 87.5% and 66.6%. Positive predictive value is 87.5%. Negative predictive value is 66.6%. Accuracy is 81.82%. The sensitivity and specificity of MRI with respect to arthroscopy in medial meniscal tears is 85.7% and 70.8% respectively. Positive predictive value is 63%, negative predictive value is 89.4%, accuracy is 76.3%.Conclusions: The present study supports that MRI is helpful in diagnosing medial meniscal and anterior cruciate ligament injuries. The negative predictive value of a MRI was found to be high for all structures of the knee joint and hence a MRI can be used to exclude pathology, thus sparing patients from expensive and unnecessary surgery.