bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between parent emotional arousal and regulation and adolescents' affective brain response
Authors: Turpyn Caitlin C. , Poon Jennifer A. , Ross Corynne E. , Thompson James C. , Chaplin Tara M. 
Published: September 2017

AbstractParents' emotional functioning represents a central mechanism in the caregiving environment's influence on adolescent affective brain function. However, a paucity of research has examined links between parental emotional arousal and regulation and adolescents' affective brain function. Thus, the present study examined associations between parents' self‐rated negative emotion, parent emotion regulation difficulties, and adolescent brain responsivity to negative and positive emotional stimuli. Participants included 64 12–14 year‐old adolescents (31 females) and their female primary caregivers. Adolescents viewed negative, positive, and neutral emotional stimuli during an fMRI scanning session. Region of interest analyses showed that higher parent negative emotion was related to adolescents' greater ACC and vmPFC response to both negatively‐ and positively‐valenced emotional stimuli; whereas, parent negative emotion was related to adolescents' greater amygdala response to negative emotional stimuli only. Furthermore, parent emotion regulation moderated the association between parent negative emotion and adolescents' brain response to negative emotional stimuli, such that parents with high negative emotion and high emotion regulation difficulties had adolescents with the greatest affective brain response. Findings highlight the importance of considering both parent emotional arousal and regulation in understanding the family affective environment and its relation to adolescent emotion‐related brain development.
Influence of preoperative septic peritonitis and anastomotic technique on the dehiscence of enterectomy sites in dogs: A retrospective review of 210 anastomoses
Authors: Davis Daniel J. , Demianiuk Ryan M. , Musser Jon , Podsiedlik Maria , Hauptman Joe 
Published: September 2017

AbstractObjectiveTo determine the influence of preoperative septic peritonitis (PSP) and stapled versus hand‐sewn anastomoses on the dehiscence of intestinal resection and anastomosis (IRA). We hypothesized that the incidence of IRA dehiscence would be greater (1) when performed with PSP and (2) for hand‐sewn anastomoses.Study designRetrospective.Animal populationsClient‐owned dogs at Michigan State University Veterinary Teaching Hospital.MethodsRecords of dogs surviving 72 hours after IRAs between 2003 and 2013 were reviewed for age, gender, neuter status, weight, presence of PSP, preoperative albumin, IRA indication and location, anastomotic technique, suture type, postoperative dehiscence and timing, duration of hospitalization, last follow‐up, and other complications. Univariate logistic regression and chi‐square analysis were used to screen prognostic factors; factors withP < .3 were included in a multivariate analysis.ResultsTwo hundred and ten IRAs in 198 dogs fulfilled the inclusion criteria. Dehiscence was diagnosed in 11.4% cases, 6.6% without PSP, and 21.1% with PSP (P = .01). Indication for IRA did not influence the risk of dehiscence. No association was detected between anastomotic technique and IRA dehiscence in dogs without PSP (stapled 4.2%, hand‐sewn 8.1%); however, stapled anastomoses were less likely to dehisce in dogs with PSP (stapled 9.7%, hand‐sewn 28.9%). Risk factors for dehiscence included PSP (P = .005) and hand‐sewn technique (P = .02).ConclusionOur results confirmed that PSP is a risk factor for dehiscence of IRA and suggest that patients with PSP may be a unique surgical population, in which stapling may be preferred over hand‐sewn anastomoses after enterectomies.
A 9-Week Jaques-Dalcroze Eurhythmics Intervention Improves Single and Dual-Task Gait Speed in Community-Dwelling Older People
Authors: Ferguson-Stegall Lisa , Vang Mandy , Wolfe Anthony S. , Thomsen Kathy M. 
Published: September 2017

Background:Falls are a major public health concern among older adults, and most occur while walking, especially under dualtask conditions. Jaques-Dalcroze eurhythmics (JDE) is a music-based movement training program that emphasizes multitask coordinated movement. A previous 6-mo JDE study in older people demonstrated improved gait and balance; however, the effects of short-term JDE interventions on fall risk-related outcomes are largely unknown. We conducted a preliminary investigation on whether a 9-week JDE intervention improved gait and stability in a community-dwelling older cohort, hypothesizing that improvements would occur in all outcome measures.Methods:Nine participants (78.9 ± 12.3 y) completed the supervised JDE intervention (once/week for 60 min). Gait speed was determined by the 6-m timed walk test (6MTW); dual-task gait speed was determined by another 6MTW while counting backward from 50 aloud; and coordinated stability was assessed using a Swaymeter-like device.Results:Gait speed (0.92 ± 0.11 vs 1.04 ± 0.12 m/sec, P = .04) and dual-task gait speed (0.77 ± 0.09 vs 0.92 ± 0.11 m/sec, P = .0005) significantly improved.Conclusions:This novel intervention is an effective short-term physical activity option for those that plan physical activity or fall-risk reduction programs for the older people.
Draft Genome Sequence of
Cercospora
cf.
sigesbeckiae
, a Causal Agent of Cercospora Leaf Blight on Soybean
Authors: Albu Sebastian , Sharma Sandeep , Bluhm Burton H. , Price Paul P. , Schneider Raymond W. , Doyle Vinson P. 
Published: September 2017

ABSTRACT

Cercospora
cf.
sigesbeckiae
is an ascomycete fungal pathogen that infects various plants, including important agricultural commodities, such as soybean. Here, we report the first draft genome sequence and assembly of this pathogen.
Draft Genome Sequence of the Type Strain Sphingopyxis witflariensis DSM 14551
Authors: Kaminski Michal A. , Furmanczyk Ewa M. , Dziembowski Andrzej , Sobczak Adam , Lipinski Leszek 
Published: September 2017

ABSTRACT

Here, we present the draft genome sequence of
Sphingopyxis witflariensis
strain DSM 14551. The assembly consists of 38 contigs and contains 4,306,761 bp, with a GC content of 63.3%.
Genome Sequence of Bradyrhizobium mercantei Strain SEMIA 6399
T
, Isolated from Nodules of
Deguelia costata
in Brazil
Authors: Ribeiro Renan Augusto , Helene Luisa Caroline Ferraz , Delamuta Jakeline Renata Marçon , Hungria Mariangela 
Published: September 2017

ABSTRACT

SEMIA 6399
T
is the type strain of
Bradyrhizobium mercantei
, a nitrogen-fixing symbiont of
Deguelia costata
. Its draft genome contains 8,842,857 bp with 8,246 predicted coding sequences (CDS), several related to amino acids and derivatives and to stress tolerance, with an emphasis on oxidative stress, in addition to symbiotic genes.
Genome Sequence of Ralstonia pseudosolanacearum Strains with Compatible and Incompatible Interactions with the Major Tomato Resistance Source Hawaii 7996
Authors: Albuquerque Greecy M. R. , Souza Elineide B. , Silva Adriano M. F. , Lopes Carlos A. , Boiteux Leonardo S. , Fonseca Maria Esther de N. 
Published: September 2017

ABSTRACT

We report here the complete genome sequences of two
Ralstonia pseudosolanacearum
strains, isolated from the warm northeast region of Brazil. They display divergent (compatible versus incompatible) interactions with the resistant tomato line Hawaii 7996. Polymorphisms were detected in a subset of effector genes that might be associated with these contrasting phenotypes.
Genome Sequence of Oceanimonas doudoroffii ATCC 27123
T
Authors: Brennan Marc A. , Trachtenberg Ariel M. , McClelland William D. , MacLea Kyle S. 
Published: September 2017

ABSTRACT

Oceanimonas doudoroffii
ATCC 27123
T
is an obligately aerobic Gram-negative rod of the class
Gammaproteobacteria
. It was first isolated from surface seawater off the coast of Oahu, HI, USA, in 1972. The predicted genome size is 3,832,938 bp (G+C content, 60.03%), which contains 3,524 predicted coding sequences.
Genome Sequence of a Novel Picorna-Like RNA Virus from Feces of the Antarctic Fur Seal (
Arctocephalus gazella
)
Authors: Krumbholz Andi , Groth Marco , Esefeld Jan , Peter Hans-Ulrich , Zell Roland 
Published: September 2017

ABSTRACT

A novel RNA virus was detected in a fecal sample collected from the Antarctic fur seal (
Arctocephalus gazella
) in King George Island, Antarctica. The almost-complete genome sequence reveals two open reading frames and a dicistrovirus-like gene order.
Draft Genome Sequence of the Marine Bacterium Oceanimonas baumannii ATCC 700832
T
Authors: McClelland William D. , Trachtenberg Ariel M. , Brennan Marc A. , MacLea Kyle S. 
Published: September 2017

ABSTRACT

The aerobic phenol-degrading Gram-negative rod
Oceanimonas baumannii
ATCC 700832
T
was first isolated from estuary mud from the River Wear, United Kingdom, in 1983. Information on the draft genome sequence for
O. baumannii
ATCC 700832
T
is included in this announcement. The predicted genome size is 3,809,332 bp, with 55.88% G+C content.
Engagement and outcomes in a digital Diabetes Prevention Program: 3-year update
Authors: Sepah S Cameron , Jiang Luohua , Ellis Robert J , McDermott Kelly , Peters Anne L 
Published: September 2017

ObjectiveTranslations of the Diabetes Prevention Program (DPP) have proliferated in recent years, with increasing expansion to digital formats. Although these DPP translations have consistently shown favorable clinical outcomes, long-term data for digital formats are limited. This study’s objective was to examine clinical outcomes up to 3 years post-baseline and the relationship between program engagement and clinical outcomes in a digital DPP.Research design and methodsIn a single-arm, non-randomized trial, 220 patients previously diagnosed with prediabetes were enrolled in the Omada Health Program, a commercially available, 16-week DPP-based weight loss intervention followed by an ongoing weight maintenance intervention. Changes in body weight and A1c were assessed annually. Relationships between program engagement during the first year and clinical outcomes across 3 years were examined.ResultsParticipants were socioeconomically diverse (62% women, 50.2% non-Hispanic white, 51.7% college educated or higher). From baseline to 3 years, those participants who completed four or more lessons and nine or more lessons achieved significant sustained weight loss (–3.0% and –2.9%, respectively) and an absolute reduction in A1c (–0.31 and –0.33, respectively) with an average remission from the prediabetes range to the normal glycemic range. Factor analysis of engagement metrics during the first year revealed two underlying dimensions, one comprising lesson completion and health behavior tracking consistency, and the other comprising website logins and group participation. When these two factors were used to predict weight loss, only the logins and group participation factor was a significant predictor of weight loss at 16 weeks and 1 year.ConclusionsThis study demonstrates significant long-term reductions in body weight and A1c in a digital DPP and identifies patterns of program engagement that predict weight loss.
Hospital volume and mortality for 25 types of inpatient treatment in German hospitals: observational study using complete national data from 2009 to 2014
Authors: Nimptsch Ulrike , Mansky Thomas 
Published: September 2017

ObjectivesTo explore the existence and strength of a relationship between hospital volume and mortality, to estimate minimum volume thresholds and to assess the potential benefit of centralisation of services.DesignObservational population-based study using complete German hospital discharge data (Diagnosis-Related Group Statistics (DRG Statistics)).SettingAll acute care hospitals in Germany.ParticipantsAll adult patients hospitalised for 1 out of 25 common or medically important types of inpatient treatment from 2009 to 2014.Main outcome measureRisk-adjusted inhospital mortality.ResultsLower inhospital mortality in association with higher hospital volume was observed in 20 out of the 25 studied types of treatment when volume was categorised in quintiles and persisted in 17 types of treatment when volume was analysed as a continuous variable. Such a relationship was found in some of the studied emergency conditions and low-risk procedures. It was more consistently present regarding complex surgical procedures. For example, about 22 000 patients receiving open repair of abdominal aortic aneurysm were analysed. In very high-volume hospitals, risk-adjusted mortality was 4.7% (95% CI 4.1 to 5.4) compared with 7.8% (7.1 to 8.7) in very low volume hospitals. Theminimum volume above which risk of death would fall below the average mortality was estimated as 18 cases per year. If all hospitals providing this service would perform at least 18 cases per year, one death among 104 (76 to 166) patients could potentially be prevented.ConclusionsBased on complete national hospital discharge data, the results confirmed volume–outcome relationships for many complex surgical procedures, as well as for some emergency conditions and low-risk procedures. Following these findings, the study identified areas where centralisation would provide a benefit for patients undergoing the specific type of treatment in German hospitals and quantified the possible impact of centralisation efforts.
Prevalence and clinical characteristics of apparent therapy-resistant hypertension in patients with cardiovascular disease: a cross-sectional cohort study in secondary care
Authors: de Beus Esther , van der Sande Nicolette G C , Bots Michiel L , Spiering Wilko , Voskuil Michiel , Visseren Frank L J , Blankestijn Peter J 
Published: September 2017

ObjectivesOur aim was to investigate the prevalence of apparent therapy-resistant hypertension (aTRH) in patients with clinical manifest cardiovascular disease (CVD), and to study clinical characteristics related to aTRH in this population.SettingThe SMART (Second Manifestations of ARTerial disease) study is a large, single-centre cohort study in secondary care.ParticipantsOffice blood pressure (BP) at inclusion was used to evaluate BP control in 6191 hypertensive patients with clinical manifest (cardio)vascular disease. Therapy-resistant hypertension was defined as BP ≥140/90 mm Hg despite use of antihypertensive drugs from ≥3 drug classes including a diuretic or use of ≥4 antihypertensive drugs irrespective of BP. Logistic regression analysis was used to explore the relationship between clinical characteristics measured at baseline and presence of aTRH.ResultsThe prevalence of aTRH was 9.1% (95% CI 8.4 to 9.8). Prevalence increased with age and when albuminuria was present and was higher in patients with lower estimated glomerular filtration rate (eGFR). Presence of aTRH was related to diabetes, female sex, duration and multiple locations of vascular disease, body mass index and waist circumference. Carotid intima-media thickness was higher (0.99±0.28 vs 0.93±0.28 mm) and ankle-brachial index lower (1.07±0.20 vs 1.10±0.19) in patients with aTRH compared with patients without aTRH.ConclusionaTRH is prevalent in patients with clinical manifest CVD and is related to clinical factors known to be related with increased vascular risk, and with lower eGFR.
Artificial stone-associated silicosis: a rapidly emerging occupational lung disease
Authors: Hoy Ryan F , Baird Timothy , Hammerschlag Gary , Hart David , Johnson Anthony R , King Paul , Putt Michael , Yates Deborah H 
Published: September 2017

IntroductionArtificial stone is an increasingly popular material used to fabricate kitchen and bathroom benchtops. Cutting and grinding artificial stone is associated with generation of very high levels of respirable crystalline silica, and the frequency of cases of severe silicosis associated with this exposure is rapidly increasing.AimTo report the characteristics of a clinical series of Australian workers with artificial stone-associated silicosis.MethodsRespiratory physicians voluntarily reported cases of artificial stone-associated silicosis identified in their clinical practices. Physicians provided information including occupational histories, respiratory function tests, chest radiology and histopathology reports, when available.ResultsSeven male patients were identified with a median age of 44 years (range 26–61). All were employed in small kitchen and bathroom benchtop fabrication businesses with an average of eight employees (range 2–20). All workplaces primarily used artificial stone, and dust control measures were poor. All patients were involved in dry cutting artificial stone. The median duration of exposure prior to symptoms was 7 years (range 4–10). Six patients demonstrated radiological features of progressive massive fibrosis. These individuals followed up over a median follow-up period of 16 months (IQR 21 months) demonstrated rapid decline in prebronchodilator forced expiratory volume in 1 s of 386 mL/year (SD 204 mL) and forced vital capacity of 448 mL/year (SD 312 mL).ConclusionsThis series of silicosis in Australian workers further demonstrates the risk-associated high-silica content artificial stone. Effective dust control and health surveillance measures need to be stringently implemented and enforced in this industry.
Cretaceous sedimentation along the Romanian margin of the Black Sea: inferences from onshore to offshore correlations
Authors: Krezsek C. , Bercea R.-I. , Tari G. , Ionescu G. 
Published: September 2017

Abstract
It is generally believed that the western part of the Black Sea opened during the Early Cretaceous. However, recent data and interpretation from the Turkish margin suggest rifting continued into the Coniacian or Santonian. In this review, the evidence related to the Black Sea rifting on the conjugate Romanian margin is reassessed. Our integrated interpretation of this region, supported by outcrop observations, core and detrital zircon data, suggests that rifting started during the Aptian and continued intermittently until the mid-Turonian in two distinct stages. These stages are bounded by significant unconformities and reflect the progressive widening of the rift system. The first synrift stage started in the Aptian with the deposition of fluvial and lacustrine clastic successions, and locally marine carbonates in semi-isolated depocentres. These sinks began to coalesce during the latest Aptian–Albian with shallow-marine transgression from the east, and deposition of coastal swamp, deltaic and littoral facies. The second phase of rifting during the Cenomanian was marked by transgressive shallow-marine deposits overstepping the earlier Albian depocentres. Continental break-up followed in the mid-Turonian associated with regional uplift and erosion of the basin margin and the local deposition of fluvial conglomerates.
The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis
Authors: Brown Isola A. M. , Gulbransen Brian D. 
Published: September 2017

Enteric glia play an important neuroprotective role in the enteric nervous system (ENS) by producing neuroprotective compounds such as the antioxidant reduced glutathione (GSH). The specific cellular pathways that regulate glial production of GSH and how these pathways are altered during, or contribute to, neuroinflammation in situ and in vivo are not fully understood. We investigated this issue using immunohistochemistry to localize GSH synthesis enzymes within the myenteric plexus and tested how the inhibition of GSH synthesis with the selective inhibitor l-buthionine sulfoximine impacts neuronal survival and inflammation. Both enteric glia and neurons express the cellular machinery necessary for GSH synthesis. Furthermore, glial GSH synthesis is necessary for neuronal survival in isolated preparations of myenteric plexus. In vivo depletion of GSH does not induce colitis but alters myenteric plexus neuronal phenotype and survival. Importantly, global depletion of glutathione is protective against some macroscopic and microscopic measures of colonic inflammation. Together, our data highlight the heterogeneous roles of GSH in the myenteric plexus of the ENS and during gastrointestinal inflammation.NEW & NOTEWORTHY Our results show that both enteric glia and neurons express the cellular machinery necessary for glutathione (GSH) synthesis and that glial GSH synthesis is necessary for neuronal survival in isolated enteric nervous system (ENS) preparations. In vivo depletion of GSH with the selective inhibitor l-buthionine sulfoximine is not sufficient to induce inflammation but does alter neuronal neurochemical composition and survival. Together, our data highlight novel heterogeneous roles for GSH in the ENS and during gastrointestinal inflammation.
Shock and lethality with anthrax edema toxin in rats are associated with reduced arterial responsiveness to phenylephrine and are reversed with adefovir
Authors: Suffredini Dante A. , Li Yan , Xu Wanying , Moayeri Mahtab , Leppla Stephen , Fitz Yvonne , Cui Xizhong , Eichacker Peter Q. 
Published: September 2017

Although edema toxin (ETx) and lethal toxin (LTx) contribute to Bacillus anthracis shock and lethality, the mechanisms underlying their cardiovascular effects are unclear. We have previously shown that ETx but not LTx inhibited phenylephrine-stimulated contraction of aortic rings prepared from healthy rats and that adefovir, a selective inhibitor of ETx cAMP production, blocked this effect. Here, we examined arterial function in rats that received 24-h ETx or LTx infusions. Compared with control rats, ETx reduced mean arterial pressure (MAP) and survival over 48 h ( P ≤ 0.0003) and increased plasma cAMP at 4, 24, and 48 h ( P < 0.0001) and nitric oxide (NO) at 24 and 48 h ( P ≤ 0.01). Compared with control animals, at 24- and 48-h phenylephrine stimulation of aortic rings from ETx animals produced decreased maximal contractile force (MCF; P = 0.05 and 0.006) and in vivo phenylephrine infusion in ETx animals produced decreased proportional increases in MAP ( P < 0.0001 and P = 0.05). In ETx-treated animals, compared with placebo-treated animals, adefovir treatment prevented all lethality ( P = 0.01), increased MAP ( P ≤ 0.0001), decreased plasma and aortic tissue cAMP at 24 and 48 h, respectively ( P ≤ 0.03), and plasma NO at both times ( P ≤ 0.004), and increased phenylephrine-stimulated increases in MCF in aortic rings and MAP in vivo at 48 h ( P = 0.02). LTx decreased MAP and survival also, but it did not alter the response to phenylephrine of MCF in aortic rings prepared from LTx animals or of MAP in vivo. In conclusion, in rats, hypotension and lethality are associated with reduced arterial contractile function with ETx but not LTx and adefovir improves ETx-induced hypotension and lethality. NEW & NOTEWORTHY The most important aspects of the present study are the findings that 1) in vivo challenge with anthrax edema but not lethal toxin depresses arterial contractile function measured both ex vivo and in vivo and 2) adefovir inhibits the effects of edema toxin on arterial hypotension and improves survival with lethal dose of edema toxin challenge.