bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study on the Efficacy of Kirschner Wire Tension Band Combined with Anchor Cross-Suture Internal Fixation versus Partial Patellectomy in the Treatment of Comminuted Inferior Pole Patellar Fractures
Authors: Duan Siyu , Xu Rongda , Liu Hanfei , Sun Ming , Liang HaiRui , Cai Zhencun 
Published: October 2024

Abstract

Objective
The treatment of comminuted inferior pole patellar fractures has long posed a challenge for orthopedic surgeons. This study aims to compare the biomechanical stability and clinical efficacy of Kirschner wire tension band combined with anchor cross-suture fixation versus traditional partial patellectomy in the treatment of comminuted inferior pole patellar fractures.
Methods
A retrospective analysis was conducted on 14 patients who underwent Kirschner wire tension band combined with anchor cross-suture fixation (Group A) in our department of orthopedics from September 2020 to April 2022. Additionally, we matched 14 patients with similar baseline characteristics who received inferior pole patellectomy combined with patellar ligament repair (Group B). The two groups were compared in terms of operative time, intraoperative blood loss, postoperative complications, and at the final follow-up, knee range of motion (ROM), visual analogue scale (VAS) score, Bostman knee function score, peak knee torque, and Insall-Salvati (IS) ratio.
Results
All patients were followed up for more than 12 months. At the final follow-up, Group A showed significantly better outcomes than Group B in terms of knee range of motion (ROM), Bostman knee function score, knee VAS score, and average peak knee torque, with statistically significant differences (P < 0.05), indicating faster postoperative recovery and better clinical results in Group A. The IS ratio of the injured knee in Group B was 0.71 ± 0.66, less than 0.8, suggesting a decrease in patellar height. There were no significant differences between the two groups in terms of operative time, intraoperative blood loss, or incision length (P > 0.05). In Group A, one patient experienced complications from hardware irritation, while in Group B, one patient had postoperative knee pain, and two patients experienced knee extension weakness after cast removal and rehabilitation.
Conclusion
Kirschner wire tension band combined with anchor cross-suture fixation for the treatment of inferior pole patellar fractures yields satisfactory results. This technique provides reliable fixation, restores the original extensor mechanism, promotes early postoperative rehabilitation, and reduces the incidence of complications, making it suitable for clinical application and widespread use.
Metagenomics: A New Frontier in Pathology Testing for Gastrointestinal Pathogens
Authors: Angel Nicola Z. , Sullivan Mitchell J. , Alsheikh-Hussain Areej , Fang Liang , MacDonald Samantha , Pribyl Alena , Wills Blake , Tyson Gene , Hugenholtz Philip , Parks Donovan H. , Griffin Paul , Wood David L.A. 
Published: October 2024

Abstract

Background
Accurate and comprehensive identification of enteropathogens, causing infectious gastroenteritis, is essential for optimal patient treatment and effective isolation processes in health care systems. Traditional diagnostic techniques are well established and optimised in low-cost formats. However, thorough testing for a wider range of causal agents is time consuming and remains limited to a subset of pathogenic organisms. Metagenomic next-generation sequencing (mNGS) allows the identification of all pathogens in a sample in a single test, without a reliance on culture or introduction of target selection bias. This study aims to determine the ability to routinely apply mNGS testing, in comparison to traditional culture or polymerase chain reaction (PCR) based tests, for the identification of causal pathogens for gastrointestinal infections.
Results
The performance of mNGS, PCR and microscopy, culture and sensitivity (MCS) assays was established using 2,619 prospectively collected faecal samples from patients with symptomology indicative of infectious gastroenteritis. Commonly experienced pathogens including Aeromonasspp, Campylobacter spp, Salmonella spp and Giardia spp, in single and co-infected patients, were used to establish test outcomes. When testing for these organisms, using the combined result from both PCR and MCS testing as the comparator, the mNGS assay had clinically acceptable sensitivity (89.2-100%). Further, the mNGS assay detected 14 additional enteropathogens, that were either not detected or not tested, by initial PCR/MCS testing.
Conclusions
The advantage of mNGS compared to other syndromic testing systems is the broad range of detectable targets and the ability to interrogate samples without clinician informed or assay specific bias. With the development of newer sequencing assays, it is now feasible to test for a wide range of target organisms in a sample using a single mNGS test. Overall, the mNGS based approach enabled pathogen detection that was comparable to conventional diagnostics and was shown to have the potential to be extended for the detection of many pathogens and genes of clinical interest. In conclusion, the mNGS assay offers an easy, sample to answer workflow with rapid detection of enteropathogens and has the potential to improve diagnosis, therapy and infection control precautions.
Upper Urinary Tract Carcinoma with Primary Small Cell Neuroendocrine Cancer – Case Report and Review of Literature
Authors: Kumar Siddhant , Bhaskara Sunil Pillai , AVB Krishnakanth , Shah Abhijit , Doddamani Siddalingeshwara Chandragouda 
Published: October 2024

Abstract

Background :
Upper Urinary Tract Small Cell Neuroendocrine Ca are extremely rare carcinomas with less than forty reported cases in literature.
Case Presentation:
92 years old male with left flank pain and diagnosed to have an enhancing renal pelvic mass; which on histopathological examination was noted to have a predominant small cell carcinoma component.
Conclusion :
This case report attempts to shed a light on the patients with small cell neuroendocrine carcinoma of upper tract with it’s silent and aggressive nature.
Robotics in the Travel, Tourism, and Hospitality Sector: A Bibliometric Analysis of Publications from 2014 to 2023
Authors: Pop Corina Monica 
Published: October 2024

Abstract

This study aims to conduct a bibliometric analysis of research publications (Virkus et al. 2023) on the application of robotics in the hospitality and tourism industry (Sharma 2024). Robotics is transforming various industries, including tourism, where technologies such as service robots, social robots, intelligent robots, and mobile robots are increasingly adopted (Ladeira 2023). Publications from 2014 to 2023 were collected from the Scopus database and analyzed (Carè and Cumming 2024) based on several criteria, including document type, language, publication year, country of origin, authorship, affiliations, sources, citations, keywords, and research areas. VOSviewer was used to visualize research trends related to the application of robots in hospitality and tourism. An analysis of 110 documents revealed a consistent increase in publications over the past decade, with China leading in publication output, followed by the United Kingdom and the United States. The International Journal of Hospitality Management emerged as the most prolific journal in this field, and the University of Surrey, Guildford, was identified as the leading institution in terms of publication volume. Keyword analysis underscored the primary research areas associated with service robots in tourism. This bibliometric study highlights the expanding literature on robotics applications within the tourism sector and serves as a valuable resource for researchers and industry stakeholders seeking to understand the current state and trends in the field (Valeri and Albattat 2024).
TiO 2 Nanoparticles with Mixed Anatase-Rutile Phase Structure Doped with Different Concentrations of Iron for Photocatalytic Activity in Degrading Methylene Blue
Authors: Gareso P. L. , Heryanto H. , Suryani Sri , Tahir D. , Taba Paulina , Aryanto Didik , Alomari Ali 
Published: October 2024

Abstract

Methylene blue as dye waste test was used to facilitate the photodegradation of iron-doped anatase-rutile mixed phase TiO2 nanoparticles (NPs) under visible light, which were synthesized using the co-precipitation method. These nanoparticles were characterized using X-Ray diffraction (XRD), UV-Vis, FTIR, field emission scanning electron microscopy (FESEM), high-resolution transmission electron microscopy (HRTEM), and energy-dispersive X-Ray spectroscopy (EDX). The XRD analysis revealed that the diffraction patterns exhibited two-phase structures, namely anatase and rutile phase structures, where the intensity of the rutile phase structures was greater than that of the anatase phase structures. The Ultraviolet-Visible Spectroscopy (UV-Vis) measurements indicated that there is a reduction of the bandgap energy of the Fe-TiO2 NPs. FESEM micrographs revealed that agglomerations formed clusters, and SEM results showed that the nanoparticles aggregate to create structures on the surface that resemble edelweiss flowers. Based on Kramers-Kronig analysis, the reduction in optical phonon (Δ(𝐿𝑂−𝑇𝑂)) cm-1 difference with a decrease in the rutile fraction as a function of Fe increased. The reduction in the rutile phase fraction correlated with a decrease in photocatalytic activity, indicating that the rutile phase has a crucial role in the photodegradation process (1wt% achieve 𝑘ads rate: 0.00273 min-1). These results suggest that iron-doped anatase-rutile mixed-phase TiO2 nanoparticles are suitable as photocatalysts.
A study on optimizing the location selection problem for urban UAV distribution while accounting for obstacles
Authors: Menghan Sun , Yuance Yu , Luyao He , Yong Yang , Zailin Yang 
Published: October 2024

Abstract

This study addresses the location problem of UAV distribution centers for urban logistics services by establishing a mathematical model aimed at minimizing the total cost of UAV operations. The model incorporates various constraints, including the number of supply points, maximum distribution capacity, task-specific limitations, starting point restrictions, maximum flight distance for UAVs, altitude constraints, and obstacle avoidance requirements. This paper presents a UAV delivery flight path obstacle avoidance algorithm designed to effectively navigate obstacles in urban environments. Additionally, a genetic annealing fusion algorithm is developed to address the distribution center location model. Comparative analysis reveals that incorporating obstacle avoidance significantly enhances performance compared to scenarios without it, and the genetic annealing algorithm outperforms the traditional genetic algorithm. Finally, a sensitivity analysis is conducted on the number of distribution centers and obstacles.
Oxygen modulates cobalamin requirement but not riboflavin in Propionibacterium freudenreichii growth
Authors: Zhang Ruoxi , Sha Yuandong , Chamlagain Bhawani , Edelmann Minnamari , Savijoki Kirsi , Piironen Vieno , Deptula Paulina , Varmanen Pekka 
Published: October 2024

Abstract

Background
Vitamin B12 (cobalamin, hereafter B12) is essential for human health, particularly for neural function and DNA synthesis. It is synthesized exclusively by bacteria and archaea, with animal-derived foods serving as the primary sources for humans. Propionibacterium freudenreichii is notable for its long history of safe use in food production, its efficient B12 synthesis, and its minimal production of inactive, pseudovitamin B12. This efficiency is attributed to its oxygen-dependent biosynthesis of 5,6-dimethylbenzimidazole (DMBI), the lower ligand of vitamin B12, via the BluB enzyme. Additionally, the synthesis of another B-group vitamin, riboflavin (hereafter B2), may influence DMBI production by providing precursor molecules.
Results
Despite recent research on the metabolic pathways and gene expression of P. freudenreichii, the roles of B12 and B2 in growth under different conditions are not fully understood. In this study, we created mutants of P. freudenreichii DSM 4902 that are defective in B12 or B2 production by inactivating key biosynthesis genes, specifically bluB and ribA. Findings revealed that the growth defects of the mutants could be complemented by external provision of vitamins, demonstrating the presence of active uptake systems for both riboflavin and cobalamin. B2 was essential for growth under all atmospheric conditions tested, particularly during aerobic growth, while B12 availability affected colony-forming ability under anaerobic conditions, but not under aerobic (pO2 ~ 20%) conditions. Analysis of spent culture media indicated that P. freudenreichii produces short-chain fatty acids (SCFAs) at a reduced rate in the absence of B12. Growth experiments of mutant strains in gradually increasing concentrations of vitamins demonstrated that 0.1 µg/mL of B12 and 0.05 µg/mL of B2 are likely the minimal concentrations required to support maximal growth. Our results suggest that de novo B2 synthesis does not affect B12 synthesis when B2 is externally supplied and that oxygen availability diminishes B12 requirements during growth.
Conclusions
This study enhances our understanding of the metabolic mechanisms of P. freudenreichii, particularly the interplay between B2 and B12 under varying oxygen conditions. These insights have practical implications for optimizing B12 production in the food and supplement industries, potentially leading to more efficient and sustainable methods.
RETRACTED: Ruminococcus bromii-generated acetate alleviated Clonorchis sinensis-induced liver fibrosis in mice
Authors: Li Chun , Cheng Changsheng , Jiang Liping , Zhong Xin , Huang Guoyang , Mo Gang , Cao Deping , Peng Xiaohong 
Published: October 2024

Abstract

The authors have requested that this preprint be removed from Research Square.
Effects of differences in perioperative mouthwash on oral bacteria and postoperative complications: Sub-analysis of a mouthwash intervention study
Authors: Kamijo Junpei , Otagiri Hiroki , Yanai Kota , Tobata Haruko , Sakai Hironori , Kurita Hiroshi 
Published: October 2024

Abstract

Background
Perioperative oral management (POM) reduces the risk of postoperative complications. We previously conducted a randomized controlled feasibility study of POM using povidone iodine (PVP-I) or 0.05% cetylpyridinium chloride (CPC) and found that perioperative self-care with CPC mouthwash may support antibiotic-induced changes in the oral flora. In this sub-analysis, we investigated how use of PVP-I and CPC products in the perioperative period affects postoperative systemic inflammation.
Methods
The subjects were 78 patients scheduled to undergo surgery under general anesthesia who received POM with random assignment of mouthwash containing PVP-I (n = 38) or CPC (n = 40). White blood cell (WBC) count, serum CRP level, and fever were used as postoperative inflammatory markers for comparison between the groups. Bacteria were collected from the dorsal surface of the tongue, and the total bacterial count, operational taxonomic unit (OTU) count, and Shannon Index were analyzed.
Results
Perioperative inflammatory indices such as WBC, CRP, and body temperature were compared between groups, and only mean CRP was significantly lower in the CPC group than PVP-I group (7.0 (range: 0-19.2) mg/dL vs. 5.3 (range: 0.1–21.0) mg/dL). A significant difference was found in the CRP level between the two groups. The incidence of high CRP (≥ 5 mg/dL) was significantly lower in the CPC group (16/40, 40%) compared to the PVP-I group (24/38, 63.2%). In multivariate analysis, the intervention product was a significant independent factor related to high CRP. The lower CRP in the CPC group was associated with a lower OTU count and lower Shannon Index.
Conclusion
The results suggest that use of CPC in POM is associated with a lower CRP level. Use of mouthwash containing CPC may decrease bacterial diversity on the dorsal surface of the tongue, and this may reduce postoperative complications such as pneumonia.
Trial registration:
University Hospitals Medical Information Network Clinical Trials Registry (UMIN-CTR), UMIN000030919. Registered January 21, 2018.
Relationship between multiple inflammatory index level trajectories and 28-day mortality in patients on ECMO
Authors: Zhou You , Cheng Zhi , Sun Liqun , Han Jiayan , li Suhui , Wang Xin , Xu Leiming 
Published: October 2024

Abstract

Background: Extracorporeal membrane oxygenation (ECMO) is a simplified cardiopulmonary bypass device that provides temporary respiratory and circulatory support and adequate recovery time for the heart and lung, but the mortality rate of acute and critically ill patients undergoing ECMO is still high. Progression of systemic inflammatory response is associated with mortality in ECMO patients. The objective of this study was to investigate the dynamic changes of various inflammatory markers and their relationship with 28-day mortality in patients with ECMO.
Methods: A retrospective cohort analysis was conducted on 200 patients receiving ECMO treatment evaluating inflammatory markers including neutrophil-to-lymphocyte ratio (NLR), systemic inflammatory response index (SIRI), procalcitonin (PCT), interleukin-6 (IL-6), and C-reactive protein (CRP) at various time points. A dynamic trajectory model was constructed, and survival differences between groups were assessed using Kaplan–Meier plots and log-rank tests. Multiple Cox proportional hazard models were built to analyze the relationship between dynamic trajectories and clinical outcomes. Causal mediation analysis was applied to determine whether changes in inflammatory trajectories mediated survival outcomes in patients on ECMO through other variables.
Results: Age, Acute Physiology and Chronic Health Evaluation (APACHE) II score, and elevated aspartate aminotransferase (AST) levels significantly impacted the 28-day survival rate (p<0.05), with higher mortality observed in patients exhibiting poor inflammatory trajectories. Kaplan–Meier survival analysis revealed that patients in the ascending (AS) group had a significantly higher risk of death than those in the stable (ST) and descending (DS) groups (log-rank p<0.001). Furthermore, multivariate Cox regression analysis identified IL-6 as the most strongly correlated inflammatory marker with mortality risk [Hazard ratio (HR) = 1.97, 95% confidence interval (CI) 1.35-2.87, p<0.001].
Conclusions: This study highlights the importance of dynamic monitoring of inflammatory biomarkers in patients on ECMO, suggesting that individualized treatment adjustments based on these markers could enhance survival rates. Future research should prioritize larger, multicenter cohort studies and clinical trials to validate these findings, aiming to optimize treatment strategies for patients on ECMO.
SemiTabDETR: End-to-End Semi-Supervised Table Detection with Transformer-based Enhanced Query Approach
Authors: Shhezadi Tahira , Stricker Didier , Afzal Muhammad Zeshan 
Published: October 2024

Abstract

Table detection recognizes and accurately determines the position of tables within document images. This task involves both classification and precise localization of these table elements. Conventional table detection methods usually depend on extensive labeled data, creating a challenge in generating high-quality labels for training. To address this, many semi-supervised approaches are proposed. These methods utilize either CNN-based networks, which rely on anchor generation and NMS (Non-Maximum Suppression), or employ transformer-based models with performance linked to the quality of object queries. In this paper, we propose a transformer-based semi-supervised approach that improves the quality of object queries. We take high-level query features from unlabeled images and find similarities with decoder original queries by an enhanced query selection network. It provides high-quality, refined queries, allowing the model to make precise predictions or classifications with minimal labeled data. Results on benchmarks such as Publaynet, DocBank, PubTables, and ICDAR 19 have demonstrated that this innovative approach significantly outperforms traditional supervised and semi-supervised methods. On just 1% label data, our approach obtains 98.1% mAP, 96.4% mAP, and 82.8% mAP on PubTables, PubLayNet, and DocBank datasets, respectively. The state-of-the-art results show the effectiveness of our approach.
A checklist of invasive alien plants of Kalahandi district: one of the famous historical and ancient places of Odisha, India
Authors: Behera Ghanashyam , Nayak Nihar Ranjan , Bhatta Bandana , Padhan Jhili , Joshi Naseeb , Majhi Ranju , Charchi Sibani , Majhi Sushanta , Sahu Alok Ranjan 
Published: October 2024

Abstract

The present study was based on both bibliographic sources and the survey to the documentation of invasive plants in Kalahandi district, Odisha, India. A total of 108 species belonging to 91 genera and 37 families are reported. The highest number of species i.e. 15 no. were contributed from both the family Asteraceae and Fabaceae; followed by nine species from Poaceae; six species (Amaranthaceae); five species each from the family Convolvulaceae and Malvaceae; four species each from four families (Apocyanaceae, Euphorbiaceae, Polygonaceae and Solanaceae); three species each from two family (Acanthaceae and Lamiaceae); two species each from six family (Boraginaceae, Cyperaceae, Passifloraceae, Pontederiaceae, Salviniaceae and Verbenaceae); rest 18 families contributed one species each. The diversity of exotic plants was highest in the wasteland (52 spp.), followed by 35 species contributed from the cultivated field, roadside (30 spp.), 15 spp. each from both forest and homestead, river bed (12 spp.), and aquatic (5 spp.). Among these the maximum species contribution is from Tropical America (36 spp.), followed by North America (20 spp.), Africa (19 spp.), Asia (16 spp.), South America (14 spp.), Australia (5 spp.), Europe (4 spp.), Central America (3 spp.), both the sub-trophical America and Mediterranean contributed one species each. The uses of exotic plants for various purposes indicated by the native peoples are discussed here. The present study gives complete and efficient documentation of invasive plants in Kalahandi district of Odisha that will provide a tool for maintenance of the local biodiversity.