bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling a Predictive Energy Equation Specific for Maintenance Hemodialysis
Authors: Byham‐Gray Laura D. , Parrott J. Scott , Peters Emily N. , Fogerite Susan Gould , Hand Rosa K. , Ahrens Sean , Marcus Andrea Fleisch , Fiutem Justin J. 
Published: March 2017

AbstractBackground: Hypermetabolism is theorized in patients diagnosed with chronic kidney disease who are receiving maintenance hemodialysis (MHD). We aimed to distinguish key disease‐specific determinants of resting energy expenditure to create a predictive energy equation that more precisely establishes energy needs with the intent of preventing protein‐energy wasting. Materials and Methods: For this 3‐year multisite cross‐sectional study (N = 116), eligible participants were diagnosed with chronic kidney disease and were receiving MHD for at least 3 months. Predictors for the model included weight, sex, age, C‐reactive protein (CRP), glycosylated hemoglobin, and serum creatinine. The outcome variable was measured resting energy expenditure (mREE). Regression modeling was used to generate predictive formulas and Bland‐Altman analyses to evaluate accuracy. Results: The majority were male (60.3%), black (81.0%), and non‐Hispanic (76.7%), and 23% were ≥65 years old. After screening for multicollinearity, the best predictive model of mREE (R2 = 0.67) included weight, age, sex, and CRP. Two alternative models with acceptable predictability (R2 = 0.66) were derived with glycosylated hemoglobin or serum creatinine. Based on Bland‐Altman analyses, the maintenance hemodialysis equation that included CRP had the best precision, with the highest proportion of participants’ predicted energy expenditure classified as accurate (61.2%) and with the lowest number of individuals with underestimation or overestimation. Conclusions: This study confirms disease‐specific factors as key determinants of mREE in patients on MHD and provides a preliminary predictive energy equation. Further prospective research is necessary to test the reliability and validity of this equation across diverse populations of patients who are receiving MHD.
Patency rate and quality of life after ultrasound-accelerated catheter-directed thrombolysis for deep vein thrombosis
Authors: Gombert Alexander , Gombert Ricarda , Barbati Mohammad E. , Bruners Philipp , Keszei Andras , Wittens Cees , Jalaie Houman , Grommes Jochen 
Published: March 2017

Purpose Studies on ultrasound-accelerated, catheter-directed thrombolysis of acute deep vein thrombosis emphasize good patency rates and low complication rates. Therefore, we analyzed quality of life besides technical success and patency in our patients after ultrasound-accelerated, catheter-directed thrombolysis. Methods Between 2009 and 2014, 42 patients suffering from iliofemoral deep vein thrombosis received ultrasound-accelerated, catheter-directed thrombolysis. Follow-up included clinical exanimation and ultrasound. Thirty patients (36 interventions), mean age 41.3 years (range 19–71 years), 56.6% women (17/30), completed the surveys. Five different scores were used to assess the quality of life and symptoms of postthrombotic syndrome: SF36, Euro-QOL 5D, PDI, VEINES-QOL/Sym, and the Villalta score. Results Mean therapy duration of ultrasound-accelerated, catheter-directed thrombolysis was 76.4 h and therapeutic success could be reported in 80.5% (29/36). Successful ultrasound-accelerated, catheter-directed thrombolysis was followed by stent angioplasty in 58.3% (21/36) procedures. Overall complication rate was 19.44%, mainly formed by minor bleedings. Mean follow-up was 38.5 months. The primary patency rate was 63.8%, the assisted-primary and the secondary patency rate were 80.5%. We observed an improved quality of life in our patients’ cohort compared to patients suffering from postthrombotic syndrome. Conclusion Although ultrasound-accelerated, catheter-directed thrombolysis is feasible with good patency rates, further prospective randomized trials are necessary to evaluate the value of thrombus removal in iliofemoral deep vein thrombosis in comparison to conservative treatment.
Effects of a Flexibility/Support Intervention on Work Performance: Evidence From the Work, Family, and Health Network
Authors: Bray Jeremy W. , Hinde Jesse M. , Kaiser David J. , Mills Michael J. , Karuntzos Georgia T. , Genadek Katie R. , Kelly Erin L. , Kossek Ellen E. , Hurtado David A. 
Published: March 2017

Purpose: To estimate the effects of a workplace initiative to reduce work–family conflict on employee performance. Design: A group-randomized multisite controlled experimental study with longitudinal follow-up. Setting: An information technology firm. Participants: Employees randomized to the intervention (n = 348) and control condition (n = 345). Intervention: An intervention, “Start. Transform. Achieve. Results.” to enhance employees’ control over their work time, to increase supervisors’ support for this change, and to increase employees’ and supervisors’ focus on results. Methods: We estimated the effect of the intervention on 9 self-reported employee performance measures using a difference-in-differences approach with generalized linear mixed models. Performance measures included actual and expected hours worked, absenteeism, and presenteeism. Results: This study found little evidence that an intervention targeting work–family conflict affected employee performance. The only significant effect of the intervention was an approximately 1-hour reduction in expected work hours. After Bonferroni correction, the intervention effect is marginally insignificant at 6 months and marginally significant at 12 and 18 months. Conclusion: The intervention reduced expected working time by 1 hour per week; effects on most other employee self-reported performance measures were statistically insignificant. When coupled with the other positive wellness and firm outcomes, this intervention may be useful for improving employee perceptions of increased access to personal time or personal wellness without sacrificing performance. The null effects on performance provide countervailing evidence to recent negative press on work–family and flex work initiatives.
We’re Just Playing
Authors: Cook Mike P. , Gremo Matthew , Morgan Ryan 
Published: March 2017

Purpose. The purpose of this study was to explored the use of a tabletop role-playing game in middle school ELA classrooms to examine students’ (n=36) abilities to interact with and make meaning from a traditional classroom text (Richard Connell’s “The Most Dangerous Game”). Background.Gaming continues to soar in popularity, both inside and outside of schools. As such, it is important to continue looking for pedagogically beneficial ways to incorporate gaming into classroom spaces, specifically English Language Arts and Literacy classrooms. Aim. In this article, we describe the game used for this study was modified from the Pathfinder system and designed to pair with Connell’s short story. We also discuss our qualitative approach to data analysis, and the three themes that emerged. First, students made gaming decisions based on their knowledge of the story. Second, students experienced the narrative through the lens of their characters. And third, students engaged in meaningful collaboration throughout gameplay. Conclusion. The findings support ongoing calls to look for pedagogically beneficial ways to incorporate gaming into ELA and Literacy classroom spaces.
An excessive risk of suicide may no longer be a reality for multiple sclerosis patients
Authors: Kalson-Ray Shoshannah , Edan Gilles , Leray Emmanuelle ,   for the SURVIMUS Study Group
Published: March 2017

Background: Few recent studies have shown that there is no longer an increased risk of suicide in patients affected with multiple sclerosis (MS). Objectives: To describe suicide cases within a large French MS cohort and assess whether MS patients are at a higher risk of suicide compared with the general population. Methods: Data derives from a study on long-term mortality of 27,603 prevalent cases from 15 MS specialist centres. Of 1,569 deceased MS patients (5.7%) on 1 January 2010, 47 were suicides. Results: The mean time between MS clinical onset and death was 13.5 years (standard deviation (SD): 9.3 years; none within the first 3 years) and was significantly shorter than for MS patients who had died from other causes (mean = 21.4 (SD = 11.6), p < 0.0001). Age at death was also lower (46.3 vs 56.7). The standardized mortality rates were around 1 in several sensitivity analyses, reflecting no excess mortality in MS compared with general population. Conclusion: Our findings indicate that an excess suicide risk may no longer be true for MS patients and highlight the changing profile of cases, occurring later in the disease course. Further studies in population-based registries are needed to confirm and explain these potential changes (e.g. treatments’ impact?).
Improving Family Communication
Authors: Medrano Vilma , Bonilla Gladys , Hernández Ericka , Romanjek Mariana Harnecker , Gómez Adriana , Hernández Jasón , Reyes Marcela Ríos , Lindenberg Cathy Strachan 
Published: March 2017

Introduction: TeenSmart International harnesses the power and flexibility of technology to empower youth to take personal responsibility for their health and lifestyle choices. Access to the Internet via mobile phones is often cheaper than paying to connect to a wired broadband service, and in rural areas, mobile networks may be the only means of accessing the Internet. This study assessed the feasibility, acceptability, and impact of “cues to action” or brief motivating cell phone text messages to improve adolescent family communication and relationships. Method: A quasi-experimental design using a voluntary sample of 100 Nicaraguan youth at high risk for poor family communication participated. Pre- and posttest quantitative measures using Student t statistical analysis, a focus group, and a participant testimony provided the evaluation evidence. Results: Findings suggest that there are economic and motivational barriers to the use of text messages, but when barriers are eliminated, the behavioral results are positive. Youth who received two weekly text messages over a 6-month period demonstrated statistically significant improvements in family communication perceptions, attitudes, and behaviors, strengthening their family communications and relationships. Conclusion: Brief and personalized text messaging “cues to action” may be a cost-effective intervention to improve adolescent healthy lifestyle behaviors.
Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease
Authors: Persson Louise J.P , Aanerud Marianne , Hardie Jon A. , Miodini Nilsen Roy , Bakke Per S. , Eagan Tomas M. , Hiemstra Pieter S. 
Published: March 2017

Antimicrobial peptides (AMPs) are effectors of host defence against infection, inflammation and wound repair. We aimed to study AMP levels in stable chronic obstructive pulmonary disease (COPD) and during acute exacerbations of COPD (AECOPD), and to examine their relation to clinical parameters and inflammatory markers.The 3-year Bergen COPD Cohort Study included 433 COPD patients and 325 controls. Induced sputum was obtained and analysed for levels of the AMPs human cathelicidin (hCAP18/LL-37) and secretory leukocyte protease inhibitor (SLPI), and for the inflammatory markers interleukin (IL)-8, IL-6 and tumour necrosis factor-α (TNF-α) using immunoassays. Systemic hCAP18/LL-37 and vitamin D levels were also studied. Treating AMPs as response variables, non-parametric tests were applied for univariate comparison, and linear regression to obtain adjusted estimates. The risk of AECOPD was assessed by Cox proportional-hazard regression.Sputum AMP levels were higher in patients with stable COPD (n=215) compared to controls (n=45), and further changed during AECOPD (n=56), with increased hCAP18/LL-37 and decreased SLPI levels. Plasma hCAP18/LL-37 levels showed a similar pattern. In stable COPD, high sputum hCAP18/LL-37 levels were associated with increased risk of AECOPD, non-typeableHaemophilus influenzaecolonisation, higher age, ex-smoking and higher levels of inflammatory markers.Altered levels of selected AMPs are linked to airway inflammation, infection and AECOPD, suggesting a role for these peptides in airway defence mechanisms in COPD.
Cardiac Events After Radiation Therapy: Combined Analysis of Prospective Multicenter Trials for Locally Advanced Non–Small-Cell Lung Cancer
Authors: Dess Robert T. , Sun Yilun , Matuszak Martha M. , Sun Grace , Soni Payal D. , Bazzi Latifa , Murthy Venkatesh L. , Hearn Jason W.D. , Kong Feng-Ming , Kalemkerian Gregory P. , Hayman James A. , Ten Haken Randall K. , Lawrence Theodore S. , Schipper Matthew J. , Jolly Shruti 
Published: March 2017

Purpose Radiation therapy is a critical component in the care of patients with non–small-cell lung cancer (NSCLC), yet cardiac injury after treatment is a significant concern. Therefore, we wished to elucidate the incidence of cardiac events and their relationship to radiation dose to the heart. Patients and Materials Study eligibility criteria included patients with stage II to III NSCLC treated on one of four prospective radiation therapy trials at two centers from 2004 to 2013. All cardiac events were reviewed and graded per Common Terminology Criteria for Adverse Events (v4.03). The primary end point was the development of a grade ≥ 3 cardiac event. Results In all, 125 patients met eligibility criteria; median follow-up was 51 months for surviving patients. Median prescription dose was 70 Gy, 84% received concurrent chemotherapy, and 27% had pre-existing cardiac disease. Nineteen patients had a grade ≥ 3 cardiac event at a median of 11 months (interquartile range, 6 to 24 months), and 24-month cumulative incidence was 11% (95% CI, 5% to 16%). On multivariable analysis (MVA), pre-existing cardiac disease (hazard ratio [HR], 2.96; 95% CI, 1.07 to 8.21; P = .04) and mean heart dose (HR, 1.07/Gy; 95% CI, 1.02 to 1.13/Gy; P = .01) were significantly associated with grade ≥ 3 cardiac events. Analyzed as time-dependent variables on MVA analysis, both disease progression (HR, 2.15; 95% CI, 1.54 to 3.00) and grade ≥ 3 cardiac events (HR, 1.76; 95% CI, 1.04 to 2.99) were associated with decreased overall survival. However, disease progression (n = 71) was more common than grade ≥ 3 cardiac events (n = 19). Conclusion The 24-month cumulative incidence of grade ≥ 3 cardiac events exceeded 10% among patients with locally advanced NSCLC treated with definitive radiation. Pre-existing cardiac disease and higher mean heart dose were significantly associated with higher cardiac event rates. Caution should be used with cardiac dose to minimize risk of radiation-associated injury. However, cardiac risks should be balanced against tumor control, given the unfavorable prognosis associated with disease progression.
Interdisciplinary Decisions Application in Management, or How to Use the Experience of Workload Management of Technological System with Regard to Human Resources
Authors: Сморчкова  , Smorchkova O. 
Published: March 2017

To a modern executive officer enterprise management means challenging requirements in search of
unconventional solutions in system administration organization. A whole spectrum of solutions is found when
you use knowledge, traditions and managerial decisions existing in other spheres. This article contemplates
concepts and philosophy that consider the problem from the other point of view and find new or specialized
decisions from related areas. A comparison between workload management in technological system and
human resources is used as an example. Based on this comparison implications are made about certain
compatibility of these systems and possible adaptation of the existing management methods. At the end we
come to the conclusion of benefit from using intersectorial and cross-cultural experience.
Distinguishing Intake of New Synthetic Cannabinoids ADB-PINACA and 5F-ADB-PINACA with Human Hepatocyte Metabolites and High-Resolution Mass Spectrometry
Authors: Carlier Jeremy , Diao Xingxing , Scheidweiler Karl B , Huestis Marilyn A 
Published: March 2017

Abstract

BACKGROUND
ADB-PINACA and its 5-fluoropentyl analog 5F-ADB-PINACA are among the most potent synthetic cannabinoids tested to date, with several severe intoxication cases. ADB-PINACA and 5F-ADB-PINACA have a different legal status, depending on the country. Synthetic cannabinoid metabolites predominate in urine, making detection of specific metabolites the most reliable way for proving intake in clinical and forensic specimens. However, there are currently no data on ADB-PINACA and 5F-PINACA metabolism. The substitution of a single fluorine atom distinguishes the 2 molecules, which may share common major metabolites. For some legal applications, distinguishing between ADB-PINACA and 5F-PINACA intake is critical. For this reason, we determined the human metabolic fate of the 2 analogs.

METHODS
ADB-PINACA and 5F-PINACA were incubated for 3 h with pooled cryopreserved human hepatocytes, followed by liquid chromatography—high-resolution mass spectrometry analysis. Data were processed with Compound Discoverer.

RESULTS
We identified 19 and 12 major ADB-PINACA and 5F-ADB-PINACA metabolites, respectively. Major metabolic reactions included pentyl hydroxylation, hydroxylation followed by oxidation (ketone formation), and glucuronidation of ADB-PINACA, and oxidative defluorination followed by carboxylation of 5F-ADB-PINACA.

CONCLUSIONS
We recommend ADB-PINACA ketopentyl and hydroxypentyl, and ADB-PINACA 5-hydroxypentyl and pentanoic acid, as optimal markers for ADB-PINACA and 5F-ADB-PINACA intake, respectively. Since the 2 compounds present positional isomers as the primary metabolites, monitoring unique product ions and optimized chromatographic conditions are required for a clear distinction between ADB-PINACA and 5F-ADB-PINACA intake.
Satires of fashionable clothing and literature in nineteenth-century Russia
Authors: McQuillen Colleen 
Published: March 2017

Abstract
In early nineteenth-century Russia the categories of fashionable clothing and fashionable literature emerged side by side, which gave critics of the corresponding industries a convenient discourse for satirizing the latter in terms of the former. The writings and drawings this article examines show that the enmeshment of these two feminine economies endured for decades as a productive trope despite changes in the gendering of the garment industry around mid-century. Just as Roland Barthes asserted the legibility of fashion as a semiotic system, this study treats verbal and visual representations of clothing as legible texts that are open to interpretation. It also probes the problematic relationship among body, text and clothing in representations where the clothing is not worn on the body but rather becomes a body through the literary device of personification.
‘Retaining their bestial character’: Fashion, fear of degeneration and animal protection in late imperial Russia
Authors: Gusarova Ksenia 
Published: March 2017

Abstract
This article examines the possible roots of the change in cultural attitudes, due to which fashionable objects of animal origin started to be viewed negatively in Russian fashion periodicals and advice manuals of the early twentieth century. Among these influences, we may count the development of the animal protection movement, with the Russian Society for the Protection of Animals established in 1865. Although initially this association was not concerned with fashion, it shaped the notion of the cruel treatment of animals, drawing public attention to this issue. An analysis of non-fiction writing by Fyodor Dostoevsky and Vikentii Veresaev will show that, while the Society’s agenda was ambiguous and met with a mixed response, the new sensibilities this group promoted were increasingly internalized by the educated public.
On the other hand, fashion criticism during the era argued that fashion distorts and deforms human shape by giving it animal features – that is, it assists degeneration. A reversal of evolution, in this case triggered by brutality, was similarly evoked by the proponents of animal protection. The newly perceived inappropriateness of certain fashionable objects was thus due to the double ‘animality’ they were believed to impart to the wearer: that of following the ‘fashion instinct’ and that of being complicit in violence.
Dancing through myself: Memory, identity, spirituality
Authors: Sellers-Young Barbara 
Published: March 2017

Abstract
Influenced by the rhetorical critique of post-structuralism and the additions of such new styles of ethnographic research as sensory ethnography, there has been an increased interest in autoethnography, which has been ultimately influenced by the new research in the area of neuroscience with specific reference to embodiment. This article follows my reflections from those on ethnography to contemplation of the neuroscience of embodiment, and finally the autoethnographic project focused on embodying the spiritual.
Backstage with Loïc Prigent: Documenting process from Gaultier to Chanel
Authors: Rees-Roberts Nick 
Published: March 2017

Abstract
Seen as the leading contemporary maker of behind-the-scenes documentaries about the world of fashion, French journalist Loïc Prigent has established a career from delving into the methods and processes involved in fabricating designer fashion. His popular television series Le Jour d’avant (The Day Before) (Prigent, 2009–10) mixes traditional information and observation with a more performative and selfreflexive mode with ironic nods to factual entertainment formats and reality television. This article unpacks Prigent’s documentary method underlining his sociological precision and particular interest in the creative process through analysis of his filmed portrait of Jean-Paul Gaultier at work recreating and contextualizing his most famous designs in front of the camera. The article concludes by critiquing Prigent’s possible collusion with the luxury mega-brands arguing that his work illustrates the precarious position of the documentarian working in global fashion in the twentyfirst century, torn between a journalistic ethic of information and the lucrative lure of covert promotion.
Bedknobs and Broomsticks: The magical manipulation of dress and the heritage object in the service of wartime fantasy
Authors: Marston Kendra 
Published: March 2017

Abstract
This article explores how Disney provides a utopian response to the horror and corporeal trauma of warfare through the family musical Bedknobs and Broomsticks (Stevenson, 1971), a film in which amateur sorceress Eglantine Price (Angela Lansbury) can enchant a museum’s weapons and heritage military wear into battling the Nazis in the place of ageing members from her own community. In this film, the mobilization of and attitudes towards costume and the heritage antiquity can displace human labour in wartime, so that death, destruction and bodily injury are prevented from occurring and families are brought together as opposed to being driven apart. The article ultimately argues that while human unity and the idea of multicultural harmony are celebrated, the enchanted object provides a means of cleansing political struggle in a way that disavows the human cost of warfare rather than serving to question the nature of warfare itself.