bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing textural changes of breaded deep‐fat fried chicken nuggets during post‐frying holdings under infrared heat‐lamp using acoustic‐mechanical techniques
Authors: Liberty Jacob Tizhe , Bhuiyan Md. Hafizur Rahman , Ngadi Michael 
Published: September 2024

SummaryTexture is a multi‐parameter attribute and one of the prime quality attributes of fried products. This study examined the influence of post‐frying holdings under a heat lamp on the texture of breaded fried chicken nuggets. Chicken nuggets were deep‐fat fried (2, 4, 6, and 8 min) in canola oil at 180 °C. The fried samples were kept under an infrared heat lamp for up to 1 h, and the textural characteristics were compared with samples not exposed to post‐frying holdings. Textural characteristics were analysed through mechanical‐acoustic approach. The mechanical‐acoustic parameters related to crispiness analysed included maximum force (Fmax, N), number of force peaks (NFP), the area under force‐deformation curves (AF, N.sec), sound pressure level (SPL, dB), number of sound peaks (AUX) and the area under the amplitude‐time plots (AS, dB.sec). The mechanical parameters (Fmax: 19.11–48.96 N; NFP: 5–40; AF: 43–135 N.sec) of chicken nuggets increased with frying time, and these attributes were decreased during post‐frying holding. Similarly, acoustic parameters (SPL: 64.75–90.67 dB; AUX: 180–795; AS: 63–98 dB.sec) of chicken nuggets increased with frying time, and these attributes were decreased during post‐frying holding. Considering the studied parameters, 6 min of frying was found as optimal frying time. However, the post‐frying infrared heat lamp treatment affected the mechanical textural parametres more than the acoustic parameters. Findings from this study will be useful to food industries in optimising textural retention during post‐frying heat lamp holdings of fried products.
Characterising cricket flour from Gryllus assimilis: an alternative source of nutrients for sustainability
Authors: Toribio Ezequiel , Correa María Jimena , Medici Sandra Karina , Ferrero Cristina , Arp Carlos Gabriel 
Published: September 2024

SummaryA trend to study entomological options as food is turning the practice of entomophagy into a novel research field in search for sustainable and accessible sources of nutrients. In this work, cricket (Gryllus assimilis) was processed into flour (CF), and then extracted using different solvents to obtain oils and defatted flours. The repeatability of CF obtention, its nutritional profile, and some of its physicochemical properties were studied. Results showed repeatability with a 28% mass yield for CF production. The CF presented adequate amino acid, mineral, and fatty acid profiles, a high content of dietary fibre, and low available carbohydrates, thus being considered a suitable alternative for inclusion in healthy human diets. Using data obtained from the total nitrogen content, the amino acid profile, and the total dietary fibre determinations, the CF protein digestibility was estimated at 67.4%. Based on experimental data, a mean nitrogen‐to‐protein conversion factor of 5.76 was calculated for a G. assimilis meal. The study showed that nutritional cricket flour and derivatives can be obtained using non‐sophisticated methods.
Consumer perception of plant‐based milk alternatives: systematic review
Authors: Mekanna Alexandria Nivelle , Issa Aline , Bogueva Diana , Bou‐Mitri Christelle 
Published: September 2024

SummaryPlant‐Based Milk (PBM) alternatives have been a hype recently, drawing the high focus of investors, developers, and researchers. However, despite this surge in interest, the market size and potential of these products remain unclear. While several studies explored consumer perspectives on these alternatives, the variability in findings remains poorly understood. This systematic review aims to investigate consumer perceptions of PBM and to identify the factors associated with higher acceptance. Adhering to the PRISMA‐P methodology, searches on two major databases – Scopus and Web of Science – were conducted. Research papers published between 2019 and 2024 were screened to capture the most recent insights, resulting in thirty‐one articles. Among these studies, 71% were surveys, 50% were conducted in Europe and 46% in America. Additionally, 78% of the studies had a sample size of 500 participants or fewer, 71% assessed the perception of PBM alternative in general, while equally, 12.9% focused on soy‐based milk and 12.9% on coconut‐based milk. Overall, the studies evaluated preference for PBM over dairy milk, motives for consumption and other relevant factors. The research describes the socio‐demographic criteria associated with the high adoption rates of these products, the reasons for choosing dairy substitutes (such as curiosity, health benefits, or social influence), and the perceived advantages and barriers to their use. The expected outcomes of this study can provide valuable insights for designing effective marketing strategies for PBM and fostering the development of sustainable and healthy food systems.
Effect of ethanol concentration on conjugates of gallic acid and whey protein isolate: structural and functional properties
Authors: Zhang Ruihua , Ai Mingyan , Chen Shenghuizi , Li Shuting , Zhang Chunlan , Zhou Zhiqiang , Lu Jiankang 
Published: September 2024

SummaryThis study investigated the impact of varying ethanol concentrations on the functionality and structure of conjugates of gallic acid (GA) and whey protein isolate (WPI). The solubility, total phenolic content, and sulfhydryl group content of the conjugates significantly decreased with increasing ethanol concentration. The structure of the conjugates was altered as indicated by changes in their infrared and fluorescence spectra. By measuring the emulsification and foaming properties, we found that ethanol improved the functional properties of the conjugates. The study examined the influence of ethanol on the conjugates of polyphenolic compounds with whey protein, broadening the scope of research on protein modification. Furthermore, it provided a scientific basis for the future development of novel functional foods.
Integrated service delivery for individuals with fetal alcohol spectrum disorder
Authors: Flannigan Katherine , Edwards Devon C. , Murphy Lisa , Pei Jacqueline 
Published: September 2024

AbstractBackgroundIndividuals with fetal alcohol spectrum disorder (FASD) experience complex needs that often necessitate support from multiple systems. There is growing evidence that people with FASD may benefit from integrated service delivery (ISD), but little is known about ISD elements and processes for this population.MethodUsing a multi‐method approach involving a literature review, analysis of programme data, and staff interviews, we examined how ISD is enacted at a rural Canadian FASD centre, and identified facilitators, barriers, and potential impacts of ISD at the centre.ResultsWe describe key elements of integrated FASD programming and identify important contextual factors and themes related to ISD barriers, facilitators, and impacts: (1) connection, (2) freedom and autonomy, (3) client‐centred care, (4) learning and growth, (5) and reframing expectations.ConclusionsThis study may help to inform a roadmap for enhancing FASD service delivery and guiding FASD research and policy in Canada and beyond.
Histone deacetylase 6 controls cardiac fibrosis and remodelling through the modulation of TGF‐β1/Smad2/3 signalling in post‐infarction mice
Authors: Fang Junqiao , Shu Shangzhi , Dong Hui , Yue Xueling , Piao Jinshun , Li Shuyan , Hong Lan , Cheng Xian Wu 
Published: September 2024

AbstractHistone deacetylase 6 (HDAC6) belongs to the class IIb group of the histone deacetylase family, which participates in remodelling of various tissues. Herein, we sought to examine the potential regulation of HDAC6 in cardiac remodelling post‐infarction. Experimental myocardial infarction (MI) was created in HDAC6‐deficient (HDAC6−/−) mice and wild‐type (HADC6+/+) by left coronary artery ligation. At days 0 and 14 post‐MI, we evaluated cardiac function, morphology and molecular endpoints of repair and remodelling. At day 14 after surgery, the ischemic myocardium had increased levels of HADC6 gene and protein of post‐MI mice compared to the non‐ischemic myocardium of control mice. As compared with HDAC6−/−‐MI mice, HADC6 deletion markedly improved infarct size and cardiac fibrosis as well as impaired left ventricular ejection fraction and left ventricular fraction shortening. At the molecular levels, HDAC6−/− resulted in a significant reduction in the levels of the transforming growth factor‐beta 1 (TGF‐β1), phosphor‐Smad‐2/3, collagen I and collagen III proteins and/or in the ischemic cardiac tissues. All of these beneficial effects were reproduced by a pharmacological inhibition of HADC6 in vivo. In vitro, hypoxic stress increased the expressions of HADC6 and collagen I and III gene; these alterations were significantly prevented by the HADC6 silencing and TubA loading. These findings indicated that HADC6 deficiency resists ischemic injury by a reduction of TGF‐β1/Smad2/3 signalling activation, leading to decreased extracellular matrix production, which reduces cardiac fibrosis and dysfunction, providing a potential molecular target in the treatment of patients with MI.
A theoretical integration of work–family studies with the transactional model of stress
Authors: Ryu Geunpil 
Published: September 2024

AbstractThe work–family conflict theory posits that due to limited time and energy, individuals inevitably experience work–family role conflict, resulting in increased role strain. Conversely, the work–family enrichment theory suggests that multiple role involvement in work and family can lead to positive effects on well‐being through a virtuous cycle, known as a positive spillover effect. The theoretical review integrates work–family research with stress theory, focusing on coping behaviors and proposing a new theoretical framework. The conceptual model highlights individuals' diverse coping efforts to alleviate role strain and suggests that these strategies can result in various outcomes, including both work–family conflict and enrichment.
Visualization of myelin‐forming oligodendrocytes in the adult mouse brain
Authors: Yokoyama Kiichi , Hiraoka Yuichi , Abe Yoshifumi , Tanaka Kenji F. 
Published: September 2024

AbstractOligodendrocyte (OL) differentiation from oligodendrocyte precursor cells (OPCs) is considered to result in two populations: premyelinating and myelinating OLs. Recent single‐cell RNA sequence data subdivided these populations into newly formed (NFOLs), myelin‐forming (MFOLs), and mature (MOLs) oligodendrocytes. However, which newly proposed population corresponds to premyelinating or myelinating OLs is unknown. We focused on the NFOL‐specific long non‐coding oligodendrocyte 1 gene (LncOL1) and sought to label NFOLs under the control of the LncOL1 promoter using a tetracycline‐controllable gene induction system. We demonstrated that LncOL1 was expressed by premyelinating OLs and that the MFOL‐specific gene, Ctps, was not, indicating that NFOLs correspond to premyelinating OLs and that MFOLs and MOLs correspond to myelinating OLs. We then generated a LncOL1‐tTA mouse in which a tetracycline transactivator (tTA) cassette was inserted downstream from the LncOL1 transcription initiation site. By crossing the LncOL1‐tTA mice with tetO reporter mice, we generated LncOL1‐tTA::tetO‐yellow fluorescent protein (YFP) double‐transgenic (LncOL1‐YFP) mice. Although LncOL1 is non‐coding, YFP was detected in LncOL1‐YFP mice, indicating successful tTA translation. Unexpectedly, we found that the morphology of LncOL1‐tTA‐driven YFP+ cells was distinct from that of LncOL1+ premyelinating OLs and that the labeled cells instead appeared as myelinating OLs. We demonstrated from their RNA expression that YFP‐labeled OLs were MFOLs, but not MOLs. Using the unique property of delayed YFP induction, we sought to determine whether MFOLs are constantly supplied from OPCs and differentiate into MOLs, or whether MFOLs pause their differentiation and sustain this stage in the adult brain. To achieve this objective, we irradiated adult LncOL1‐YFP brains with X‐rays to deplete dividing OPCs and their progeny. The irradiation extinguished YFP‐labeled OLs, indicating that adult OPCs differentiated into MOLs during a single period. We established a new transgenic mouse line that genetically labels MFOLs, providing a reliable tool for investigating the dynamics of adult oligodendrogenesis.
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Job loss during COVID‐19 on early retirement withdrawals: A moderated‐mediation analysis
Authors: Zheng Haotian , Roll Stephen , Despard Mathieu 
Published: September 2024

AbstractThis study explores the impact of COVID‐19‐related job loss on early retirement withdrawals, highlighting the roles of financial hardships, subjective well‐being, financial knowledge, and emergency savings. Drawing from 2929 respondents, the research identified that job loss increases early withdrawals, both directly and through financial hardships and well‐being perceptions. Notably, individuals with greater financial knowledge and at least 3 months of emergency savings experience less negative impact from job loss. Our findings emphasize the vital role of employers in offering workplace financial education and promoting emergency savings. This aligns with the SECURE 2.0 Act's strategies and underlines the significance of financial readiness in buffering against the economic fallout of unexpected events like the COVID‐19 pandemic.
Evaluation of intraoperative lidocaine on the prevention of postoperative shoulder pain in gynecologic laparoscopy: A prospective randomized, double‐blind, placebo‐controlled study
Authors: Zhao Liyan , Li Bin , Li Ningkang , Bao Jiamin , Zhu Xiaoning , Hai Kerong 
Published: September 2024

AbstractAimTo assess the effectiveness of intraoperative lidocaine in reducing the incidence of post‐laparoscopic shoulder pain (PLSP) after gynecologic laparoscopy.MethodsPatients undergoing total laparoscopic hysterectomy were randomly divided into two groups: the lidocaine group, receiving an initial intravenous dose of lidocaine (1.5 mg/kg) before anesthesia induction, followed by a continuous infusion at 2 mg/kg/h, and the placebo group, receiving saline. The primary endpoint was the determination of PLSP incidence over a 72‐h period post‐surgery. Secondary endpoints included a comprehensive evaluation of pain intensity, as measured by the Numeric Rating Scale (NRS), for shoulder, abdominal, and incisional pain within a 72‐hour period postoperatively. Additionally, the endpoints involved the assessment of Lofencodeine or Parexib Sodium usage frequency, incidence of nausea and vomiting, duration of anesthesia and surgical procedure, as well as the duration of hospital stay.ResultsOur study did not demonstrate any significant benefit in the incidence of PLSP during the postoperative period. PLSP occurred in 14 out of 41 patients (34.1%) in the lidocaine group, compared with 15 out of 41 patients (36.6%) in the placebo group (p = 0.817). Intravenous lidocaine reduced abdominal pain scores and decreased the need for postoperative analgesics within 72 h after surgery. No significant differences were found in incisional and shoulder pain intensity, nausea and vomiting rates, or hospitalization duration between groups.ConclusionsThe infusion of lidocaine did not yield a reduction in the incidence or severity of PLSP in patients undergoing laparoscopic total hysterectomy.
Counteracting “the tragedy of the commons” in an imperfect world
Authors: Wiszniewska‐Matyszkiel Agnieszka , Singh Rajani 
Published: September 2024

AbstractOur research question is whether it is possible and how to counteract “the tragedy of the commons” if facing various limitations of real‐world economies. To answer it, we derive regulatory tax–subsidy systems and self‐enforcing environmental agreements in a problem of extraction of common renewable resources. The first considered limitation is that the feasible class of tax–subsidy systems may have a compl icated form, for example, there are transition periods for smooth reduction of fishing. The alternative limitation is that there is no institution that can impose taxes or subsidize, so sustainability can be achieved only by self‐enforcing international agreements. The next limitation is in those agreements: we assume that it takes time to detect a defection. We study these enforcement tools in a continuous‐time version of a Fish War type game with countries, with fish indispensable for their economies. We calculate the social optimum, a Nash equilibrium, and partial cooperation equilibria. The Nash equilibrium leads to the depletion of fish, while the social optimum typically results in sustainability. For partial cooperation, only two‐country coalitions are stable. We calculate tax–subsidy systems that enforce maximization of joint payoff, also if there are additional constraints, and we propose an algorithm that looks for such a system in an arbitrary class of regulatory tax–subsidy systems. For the international agreement with imperfect monitoring, we are interested in the maximal detection delay for which the agreement remains self‐enforcing. Counterintuitively, the more the players, the more stable the agreement.
Long COVID symptoms and sleep problems: a population‐based study
Authors: Letícia Anna , Neves Rosália Garcia , Vieira Yohana Pereira , Gonzales Tatiane Nogueira , Marochi Melissa , Reis Rodrigo Zopellaro , Machado Karla Pereira , Duro Suele Manjourany Silva , de Oliveira Saes Mirelle 
Published: September 2024

SummaryTo investigate the association between symptoms of long‐term effects of coronavirus disease 2019 (long COVID) and sleep problems in a sample population from southern Brazil. This cross‐sectional study used data from the SULcovid‐19 survey, developed in the municipality of Rio Grande, RS, Brazil. The outcome, long COVID, was investigated through the presence of 18 symptoms, and the exposure variable was sleep problems. Poisson regression with robust adjustment for variance was used to estimate crude and adjusted prevalence ratios for the outcome–exposure relationship. Odds ratio was calculated through multinomial regression of the relationship between the number of symptoms of long COVID and sleep problems. Analyses were adjusted for sex, age, marital status, income, body mass index, smoking status, comorbidities, and hospital admission. A total of 2919 adults and older adults were interviewed. The prevalence of long COVID was 48.3% (95% confidence interval [CI] 46.5–50.1%) and sleep problems were reported by 41.2% of the sample (95% CI 39.4–43.0%). Individuals with sleep problems were more likely to exhibit altered sensitivity (prevalence ratio [PR] 3.27; 95% CI 1.96–5.45), nasal congestion (PR 2.75; 95% CI 1.53–4.94), musculoskeletal symptoms (PR 1.75; 95% CI 1.48–2.06), respiratory issues (PR 1.58; 95% CI 1.24–2.01), and one or more symptom of long COVID (PR 1.27; 95% CI 1.15–1.39). Approximately one‐half of the population analysed had long COVID, and four of 10 reported experiencing sleep problems. In addition, the sample tended to have experienced a greater number of symptoms compared with those who reported to sleep well.
Tag Recycling in the Pup‐Proteasome System is Essential for Mycobacterium smegmatis Survival Under Starvation Conditions
Authors: Zerbib Erez , Levin Roni , Gur Eyal 
Published: September 2024

ABSTRACTMany bacteria possess proteasomes and a tagging system that is functionally analogous to the ubiquitin system. In this system, Pup, the tagging protein, marks protein targets for proteasomal degradation. Despite the analogy to the ubiquitin system, where the ubiquitin tag is recycled, it remained unclear whether Pup is similarly recycled, given how the bacterial proteasome does not include a depupylase. We previously showed in vitro that as Pup lacks effective proteasome degradation sites, it is released from the proteasome following target degradation, remaining conjugated to a degradation fragment that can be later depupylated. Here, we tested this model in Mycobacterium smegmatis, using a Pup mutant that is effectively degraded by the proteasome. Our findings indicate that Pup recycling not only occurs in vivo but is also essential to maintain normal pupylome levels and to support bacterial survival under starvation conditions. Accordingly, Pup recycling is an essential process in the mycobacterial Pup‐proteasome system.
Polyamine oxidation enzymes regulate sexual mating/filamentation and pathogenicity in Sporisorium scitamineum
Authors: Yin Kai , Hu Zhijian , Yuan Meiting , Chen Weidong , Bi Xinping , Cui Guobing , Liang Zhibin , Deng Yi Zhen 
Published: September 2024

AbstractSugarcane smut fungus Sporisorium scitamineum produces polyamines putrescine (PUT), spermidine (SPD), and spermine (SPM) to regulate sexual mating/filamentous growth critical for pathogenicity. Besides de novo biosynthesis, intracellular levels of polyamines could also be modulated by oxidation. In this study, we identified two annotated polyamine oxidation enzymes (SsPAO and SsCuAO1) in S. scitamineum. Compared to the wild type (MAT‐1), the ss1paoΔ and ss1cuao1Δ mutants were defective in sporidia growth, sexual mating/filamentation, and pathogenicity. The addition of a low concentration of cAMP (0.1 mM) could partially or fully restore filamentation of ss1paoΔ × ss2paoΔ or ss1cuao1Δ × ss2cuao1Δ. cAMP biosynthesis and hydrolysis genes were differentially expressed in the ss1paoΔ × ss2paoΔ or ss1cuao1Δ × ss2cuao1Δ cultures, further supporting that SsPAO‐ or SsCuAO1‐based polyamine homeostasis regulates S. scitamineum filamentation by affecting the cAMP/PKA signalling pathway. During early infection, PUT promotes, while SPD inhibits, the accumulation of reactive oxygen species (ROS) in sugarcane, therefore modulating redox homeostasis at the smut fungus–sugarcane interface. Autophagy induction was found to be enhanced in the ss1paoΔ mutant and reduced in the ss1cuao1Δ mutant. Exogenous addition of cAMP, PUT, SPD, or SPM at low concentration promoted autophagy activity under a non‐inductive condition (rich medium), suggesting a cross‐talk between polyamines and cAMP signalling in regulating autophagy in S. scitamineum. Overall, our work proves that SsPAO‐ and SsCuAO1‐mediated intracellular polyamines affect intracellular redox balance and thus play a role in growth, sexual mating/filamentation, and pathogenicity of S. scitamineum.