bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tracing the energy footprints of Indonesian manufacturing industry
Authors: Vivadinar Yales , Purwanto Widodo W. , Saputra Asep H. 
Published: November 2016

AbstractThe low energy efficiency is the source of the large energy consumption issue and the rapid growth of energy demand in the manufacturing industry sector in Indonesia. The driving forces behind the low energy efficiency situation in this sector are both economic and efficiency factors. The objective of this study is to generate the map of the energy flow in the manufacturing industry sector to investigate the energy utilization in the industrial process. The data sample that represents 80% of energy consumption in the manufacturing sector is used to generate this map. The generated map shows the heating system is the largest energy consumer among all energy equipment and as the primary source of the energy losses. Additionally, we found the industry groups such as sugar, cement, pulp and paper, and textile use enormous amounts of energy as their source for the heating system; meanwhile, the industries such as basic chemical, metal, and textile are the largest electricity consumers for their motor‐driven machinery. The energy flow analysis together with the comparison of the Specific Energy Consumption shows the areas that should be the focus for further energy conservation measures. Recommended measures are also discussed.
Euromind‐: A Density Estimate of Monthly Gross Domestic Product for the Euro Area
Authors: Proietti Tommaso , Marczak Martyna , Mazzi Gianluigi 
Published: November 2016

SummaryEuroMInd‐
is a density estimate of monthly gross domestic product (GDP) constructed according to a bottom‐up approach, pooling the density estimates of 11 GDP components, by output and expenditure type. The components' density estimates are obtained from a medium‐size dynamic factor model handling mixed frequencies of observation and ragged‐edged data structures. They reflect both parameter and filtering uncertainty and are obtained by implementing a bootstrap algorithm for simulating from the distribution of the maximum likelihood estimators of the model parameters, and conditional simulation filters for simulating from the predictive distribution of GDP. Both algorithms process the data sequentially as they become available in real time. The GDP density estimates for the output and expenditure approach are combined using alternative weighting schemes and evaluated with different tests based on the probability integral transform and by applying scoring rules. Copyright © 2016 John Wiley & Sons, Ltd.
Reference values of cardiac ventricular structure and function by steady‐state free‐procession MRI at 3.0T in healthy adult chinese volunteers
Authors: Lei Xiaolin , Liu Hong , Han Yuchi , Cheng Wei , Sun Jiayu , Luo Yong , Yang Dan , Dong Yang , Chung Yiochu , Chen Yucheng 
Published: November 2016

PurposeTo establish normal reference values of left ventricular (LV) and right ventricular (RV) dimension, volume, mass, and ejection fraction in a Chinese population using cardiac magnetic resonance imaging (MRI).Materials and MethodsA total of 120 (60 males; 60 females; 23–83 years) healthy Han Chinese subjects without cardiovascular disease or risk factors were recruited. They underwent comprehensive MRI examination at 3.0T. LV/RV morphology and function were evaluated by steady‐state free‐procession (SSFP) sequence. Parameters were analyzed according to a standard postprocessing protocol.ResultsSignificant differences in LV size, mass, volume, and ejection fraction (EF) between sexes were noted (all P < 0.05). After indexing using body surface area (BSA), LV end‐diastolic volume (EDV), and LV mass index were greater in males than in females (76.5 vs. 68.7 mL/m, P < 0.001; 52.9 vs. 45.1 g/m, P < 0.001; respectively). LVEF was lower in males than in females (64.6% vs. 67.1%, P = 0.007, respectively). RV volume was higher and RVEF lower in males compared with females (75.3 vs. 62.7 mL/m, P < 0.001; 59.9% vs. 62.6%, P = 0.001, respectively). Age was associated significantly with indices of LV and RV volume in females (left ventricular end‐diastolic volume index: r = −0.41 P = 0.001; left ventricular end‐systolic volume index: r = −0.37 P = 0.004; left ventricular end‐diastolic volume index: r = −0.53 P < 0.001; right ventricular end‐systolic volume index: r = −0.43 P < 0.001), but not in males (all P > 0.05).ConclusionThese data suggest that sex and age affect ventricular parameters in healthy Han Chinese subjects without cardiovascular disease or risk factors.Level of Evidence: 2Technical Efficacy: Stage 2J. MAGN. RESON. IMAGING 2017;45:1684–1692
Diffusion‐weighted imaging helps differentiate multiple sclerosis and neuromyelitis optica‐related acute optic neuritis
Authors: Wan Hailin , He Huijin , Zhang Fang , Sha Yan , Tian Guohong 
Published: November 2016

PurposeTo evaluate the apparent diffusion coefficient (ADC) values between multiple sclerosis (MS) and neuromyelitis optica (NMO)‐related acute optic neuritis (ON) patients and predict their optic nerve atrophy of optic coherence tomography (OCT) parameters.Materials and MethodsNineteen MS and 15 NMO‐related acute ON patients who underwent a diffusion‐weighted imaging sequence in 3.0 Tesla MR scanner and a follow‐up OCT examination after 6 months were included. The ADC values, thickness of the retinal nerve fiber layer (RNFL) and the macular ganglion cell complex (GCC) between MS and NMO related ON were assessed.ResultsThe mean ADC value of the NMO‐ON, (0.691 ± 0.195[SD]) × 10−3 mm2/s, was significantly smaller (P = 0.0133) than that of MS‐ON. The mean ADC value of MS‐ON, (0.879 ± 0.144) × 10−3 mm2/s, was significantly smaller (P < 0.0001) than that of control group, (1.025 ± 0.067) × 10−3 mm2/s. Using an ADC value smaller than 0.830 × 10−3 mm2/s as the threshold value for differentiating MS‐ON from NMO‐ON patients, the highest accuracy of 76.7%, with 75.0% sensitivity and 78.3% specificity, was obtained. The ADC value measured at the acute stage of ON was correlated with the thickness of the RNFL (r = 0.441; P = 0.006) and the GCC (r = 0.526; P < 0.0001) after 6 months.ConclusionThe ADC value might be helpful for differentiating MS‐ON from NMO‐ON patients. The decreased ADC value was correlated with optic nerve atrophy on OCT.Level of Evidence: 3Technical Efficacy: Stage 2J. MAGN. RESON. IMAGING 2017;45:1780–1785
Spatio‐temporal precipitation climatology over complex terrain using a censored additive regression model
Authors: Stauffer Reto , Mayr Georg J. , Messner Jakob W. , Umlauf Nikolaus , Zeileis Achim 
Published: November 2016

ABSTRACTFlexible spatio‐temporal models are widely used to create reliable and accurate estimates for precipitation climatologies. Most models are based on square root transformed monthly or annual means, where a normal distribution seems to be appropriate. This assumption becomes invalid on a daily time scale as the observations involve large fractions of zero observations and are limited to non‐negative values.We develop a novel spatio‐temporal model to estimate the full climatological distribution of precipitation on a daily time scale over complex terrain using a left‐censored normal distribution. The results demonstrate that the new method is able to account for the non‐normal distribution and the large fraction of zero observations. The new climatology provides the full climatological distribution on a very high spatial and temporal resolution, and is competitive with, or even outperforms existing methods, even for arbitrary locations.
Quality assessment of dried okara as a source of production of gluten‐free flour
Authors: Ostermann‐Porcel María V , Rinaldoni Ana N , Rodriguez‐Furlán Laura T , Campderrós Mercedes E 
Published: November 2016

AbstractBACKGROUNDOkara is a by‐product of soymilk and of tofu elaboration that is rich in protein, fiber and vegetable oils as a source of gluten‐free flour. In order to take advantage of the nutritional characteristics of okara and to be able to determine an appropriate drying methodology, microwave, rotary dryer and freeze‐drying were assessed. Furthermore, flour with an enzymatic treatment was characterized as well as its functional, physicochemical, and textural properties.RESULTSThe results showed that the physiochemical characteristics of the flour were affected by the drying process, reaching adequate water content, and high protein and fiber content. The freeze‐drying process produced clearer flours with porous structure and high water absorption capacity, and with a higher protein denaturation. Okara dried by microwave and rotary dryer exhibited a denser structure with similar functional properties and improved textural characteristics such as firmness and consistency. The microwave‐produced flour was darker due to the non‐enzymatic browning reactions. The enzymatic treatment employed improved the consistency of the flour.CONCLUSIONIt was possible to choose the drying process to be applied according to the feasible use of the flour, intended to preserve the favorable nutritional aspects of the okara flour. Based on the results, it can be affirmed that the physicochemical properties and attributes of okara are influenced by the drying process employed. Okara dried by freeze‐drying resulted in a better product because it had a low final moisture content and the highest whiteness index. The flour presented a porous structure with high solubility, which is an indicator of potential applications in foods developments. © 2016 Society of Chemical Industry
Predictors of survival in posterior cricoid squamous cell carcinoma: A study of 248 cases
Authors: Din Hassieb A. , Zhan Kevin Y. , Boling Caitlin , Nguyen Shaun , Lentsch Eric J. 
Published: November 2016

ObjectivesWe aimed to describe the presentation, treatment patterns, and survival characteristics of posterior cricoid squamous cell carcinoma (SCC) with the National Cancer Database (NCDB).Study DesignRetrospective database review.MethodsWe reviewed the NCDB from 2004 to 2013. Primary, previously untreated cases of posterior cricoid SCC were studied. Cox regression analysis was performed to look for prognostic factors.ResultsOut of 14,416 hypopharyngeal malignancies, 269 (1.8%) posterior cricoid tumors were identified, of which 248 (92.2%) were SCC. Mean age at diagnosis was 65 years (range 20–90+). Most patients were Caucasian (74.7%) and male (77.1%). By presentation, 58% were classified as clinical stage tumor (cT) 3 or cT4 to cT4 disease and 57.4% were clinical node (cN) +. Radiation (RT) alone was the most common form of treatment (32.1%), followed by chemoradiation (CRT) (31.7%) and surgery plus RT (7.4%). Overall 5‐ and 10‐year survival was 25% and 19%, respectively. Significant prognostic factors include overall clinical stage III to IV (hazard ratio [HR] 1.8 [95% confidence interval (CI) 1.15–2.82], P = 0.011), clinical nodal disease (HR 1.54 [95% CI 1.10–2.15], P = 0.012), and Charlson/Deyo comorbidity score > 1 (HR 1.94 [95% CI 1.14–3.29], P = 0.014) on univariate analysis.ConclusionPosterior cricoid SCCs are rare hypopharyngeal malignancies with a poor prognosis. They typically present at late stage with nodal metastasis and are most commonly treated nonsurgically with primary RT or CRT. Increasing clinical stage, comorbidity, and nodal disease are associated with worse survival.Level of Evidence4. Laryngoscope, 127:1093–1096, 2017
Voice outcome and voice‐related quality of life after surgery for pediatric laryngotracheal stenosis
Authors: Pullens Bas , Hakkesteegt Marieke , Hoeve Hans , Timmerman Marieke , Joosten Koen 
Published: November 2016

ObjectivesTo evaluate the long‐term outcome of voice quality and voice‐related quality of life after open airway surgery for pediatric laryngotracheal stenosis.Study DesignProspective cohort study.MethodsChildren under the age of 18 years at time of follow‐up and with a history of open airway surgery for acquired laryngotracheal stenosis were included in this analysis. To assess voice‐related quality of life, the pediatric voice handicap (pVHI) index was completed by the patients' parents. The dysphonia severity index (DSI) was used as an objective measurement for voice quality.ResultsFifty‐five parents completed the pVHI, and 38 children completed the DSI. This showed high pVHI values and low total DSI scores, indicating significant voice disturbance. After multivariate analysis, the presence of comorbidities and glottic involvement of the stenosis are associated with poor long‐term voice‐related quality of life.ConclusionSignificant voice disturbance is common after surgery for pediatric laryngotracheal stenosis. Glottic involvement of the stenosis and comorbidities is associated with poor voice‐related quality of life. Evaluation of pre‐ and postoperative voice quality and voice‐related quality of life is advised for children treated for laryngotracheal stenosis.Level of Evidence2B. Laryngoscope, 127:1707–1711, 2017
Material limits of multicrystalline silicon from state‐of‐the‐art photoluminescence imaging techniques
Authors: Schindler Florian , Giesecke Johannes , Michl Bernhard , Schön Jonas , Krenckel Patricia , Riepe Stephan , Warta Wilhelm , Schubert Martin C. 
Published: November 2016

AbstractThis work reports on state‐of‐the‐art silicon material characterization by calibrated photoluminescence (PL) imaging. PL imaging techniques allow for a characterization of a large variety of material properties, ranging from bulk and surface recombination properties of bare silicon ingots, to crystal structure, dopant concentration, and bulk lifetime of silicon wafers up to material limiting impurities. In combination with solar cell simulations, injection‐dependent PL imaging of processed wafers provides a method for determining the material's efficiency potential. In this contribution, we present two methods for imaging the concentration of interstitial iron at passivated silicon slices and at unpassivated silicon ingots. The latter is achieved by our latest progress in PL‐based charge carrier bulk lifetime measurements with highest sensitivity, giving access to the bulk recombination properties of the ingot. Additionally, we present an improved analysis of specific loss mechanisms in silicon based on de‐smeared injection‐dependent lifetime images of processed wafers, which is demonstrated on the example of the bulk‐related efficiency limitations in n‐type high‐performance multicrystalline silicon. This latest progress rounds off the established techniques, enhancing the potential of PL‐based imaging techniques for a comprehensive assessment of silicon material quality, from limitations in bare silicon ingots to efficiency loss mechanisms in processed samples. Copyright © 2016 John Wiley & Sons, Ltd.
Efficient ring signature schemes over NTRU Lattices
Authors: Zhang YanHua , Hu Yupu , Xie Jia , Jiang Mingming 
Published: November 2016

AbstractTwo ring signature schemes over number theory research unit (NTRU) lattices are presented. The first scheme constructed in the random oracle model is an extension of Ducas, Lyubashevsky, and Prest's identity‐based encryption scheme over NTRU lattices (in Asiacrypt 2014). Moreover, motivated by Boyen's lattice mixing and vanishing trapdoors (in PKC 2010), the second scheme in the standard model is achieved. Under the chosen‐message attack, our new constructions are proved strongly existentially unforgeable, and the security can be reduced to the hardness of NTRU lattices. Compared with the existing lattice‐based ring signatures, our schemes are more efficient and with shorter signature length. Copyright © 2016 John Wiley & Sons, Ltd.
On the Logic of Expansion in Natural Language
Authors: Morrill Glyn , Valentín Oriol 
Published: November 2016

AbstractWe consider, for intuitionistic categorial grammar, an iteration modality with a rule of Mingle and an infinitary left rule, similar to infinitary action logic. Newly, we give Curry-Howard labelling for the iteration modality, in terms of lists, and we prove soundness and completeness of displacement calculus with additives and this modality, for phase semantics. This result has as a corollary semantic Cut-elimination. We review linguistic application of the iteration modality to unbounded addicity iterated coordination, and we present an application of a calibrated version of the iteration modality to an unbounded addicity respectively construction, this being to our knowledge the first account of respectively taking care of cases $$n>2$$

n
>
2

.
XMG 2: Describing Description Languages
Authors: Petitjean Simon , Duchier Denys , Parmentier Yannick 
Published: November 2016

AbstractThis paper introduces XMG 2, a modular and extensible tool for various linguistic description tasks. Based on the notion of meta-compilation (that is, compilation of compilers), XMG 2 reuses the main concepts underlying XMG, namely logic programming and constraint satisfaction, to generate on-demand XMG-like compilers by assembling elementary units called bricks. This brick-based definition of compilers permits users to design description languages in a highly flexible way. In particular, it makes it possible to support several levels of linguistic description (e.g. syntax, morphology) within a single description language. XMG 2 aims to offer means for users to easily define description languages that fit as much as possible the linguistic intuition.
Strong and Weak Quantifiers in Focused NL$$_{\text {CL}}$$
Authors: Kokke Wen 
Published: November 2016

AbstractWe propose an improvement of Barker and Shan’s [4] NL$$_{\text {CL}}$$

CL

for which derivability is decidable, which has a normal-form for proof search, can analyse scope islands, and distinguish between strong and weak quantifiers.
Engineering the leucine biosynthetic pathway for isoamyl alcohol overproduction in Saccharomyces cerevisiae
Authors: Yuan Jifeng , Mishra Pranjul , Ching Chi Bun 
Published: November 2016

Abstract
Isoamyl alcohol can be used not only as a biofuel, but also as a precursor for various chemicals. Saccharomyces cerevisiae inherently produces a small amount of isoamyl alcohol via the leucine degradation pathway, but the yield is very low. In the current study, several strategies were devised to overproduce isoamyl alcohol in budding yeast. The engineered yeast cells with the cytosolic isoamyl alcohol biosynthetic pathway produced significantly higher amounts of isobutanol over isoamyl alcohol, suggesting that the majority of the metabolic flux was diverted to the isobutanol biosynthesis due to the broad substrate specificity of Ehrlich pathway enzymes. To channel the key intermediate 2-ketosiovalerate (KIV) towards α-IPM biosynthesis, we introduced an artificial protein scaffold to pull dihydroxyacid dehydratase and α-IPM synthase into the close proximity, and the resulting strain yielded more than twofold improvement of isoamyl alcohol. The best isoamyl alcohol producer yielded 522.76 ± 38.88 mg/L isoamyl alcohol, together with 540.30 ± 48.26 mg/L isobutanol and 82.56 ± 8.22 mg/L 2-methyl-1-butanol. To our best knowledge, our work represents the first study to bypass the native compartmentalized α-IPM biosynthesis pathway for the isoamyl alcohol overproduction in budding yeast. More importantly, artificial protein scaffold based on the feature of quaternary structure of enzymes would be useful in improving the catalytic efficiency and the product specificity of other enzymatic reactions.
A survey on biomarker identification based on molecular networks
Authors: Zhu Guanghui , Zhao Xing‐Ming , Wu Jun 
Published: November 2016

BackgroundIdentifying biomarkers for accurate diagnosis and prognosis of diseases is important for the prevention of disease development. The molecular networks that describe the functional relationships among molecules provide a global view of the complex biological systems. With the molecular networks, the molecular mechanisms underlying diseases can be unveiled, which helps identify biomarkers in a systematic way.ResultsIn this survey, we report the recent progress on identifying biomarkers based on the topology of molecular networks, and we categorize those biomarkers into three groups, including node biomarkers, edge biomarkers and network biomarkers. These distinct types of biomarkers can be detected under different conditions depending on the data available.ConclusionsThe biomarkers identified based on molecular networks can provide more accurate diagnosis and prognosis. The pros and cons of different types of biomarkers as well as future directions to improve the methods for identifying biomarkers are also discussed.
Guidelines to improve animal study design and reproducibility for Alzheimer's disease and related dementias: For funders and researchers
Authors: Snyder Heather M. , Shineman Diana W. , Friedman Lauren G. , Hendrix James A. , Khachaturian Ara , Le Guillou Ian , Pickett James , Refolo Lorenzo , Sancho Rosa M. , Ridley Simon H. 
Published: November 2016

AbstractThe reproducibility of laboratory experiments is fundamental to the scientific process. There have been increasing reports regarding challenges in reproducing and translating preclinical experiments in animal models. In Alzheimer's disease and related dementias, there have been similar reports and growing interest from funding organizations, researchers, and the broader scientific community to set parameters around experimental design, statistical power, and reporting requirements. A number of efforts in recent years have attempted to develop standard guidelines; however, these have not yet been widely implemented by researchers or by funding agencies. A workgroup of the International Alzheimer's disease Research Funder Consortium, a group of over 30 research funding agencies from around the world, worked to compile the best practices identified in these prior efforts for preclinical biomedical research. This article represents a consensus of this work group's review and includes recommendations for researchers and funding agencies on designing, performing, reviewing, and funding preclinical research studies.
Trend in aggregate idiosyncratic volatility
Authors: Nam Kiseok , Khaksari Shahriar , Kang Moonsoo 
Published: November 2016

AbstractWe suggest that price interaction among stocks is an important determinant of idiosyncratic volatility. We demonstrate that as more (less) stocks are listed in the markets, price interaction among stocks increases (decreases), and hence stocks, on average, become more (less) volatile. Our results show that price interaction has a significant positive effect of idiosyncratic volatility. The results of various robustness checks indicate that the effect of price interaction is still significant to the presence of liquidity, newly listed firms, cash flow variables, business cycle variables, and market volatility. Once the price interaction effect is taken into account, no trend remains in idiosyncratic volatility. We conclude that there is no trend, but a reflection of the positive effect of price interaction on idiosyncratic volatility.