bluuebunny/crossref_metadata_2025_split huggingface dataset:
Covariant quantisation of tensor multiplet models
Authors: Kuzenko Sergei M. , Raptakis Emmanouil S. N. 
Published: September 2024

Abstract
The Batalin-Vilkovisky formalism is applied to quantise the $$ \mathcal{N} $$
N
= 1 supersymmetric generalisation of the Freedman-Townsend (FT) model, which was proposed by Lindström and Roček in 1983 in Minkowski superspace and is lifted to a supergravity background in this paper. This super FT theory describes a non-Abelian tensor multiplet and is known to be classically equivalent to a supersymmetric nonlinear sigma model. Using path integral considerations, we demonstrate that this equivalence holds at the quantum level in the sense that the quantum supercurrents in the two theories coincide. A modified Faddeev-Popov procedure is employed to quantise models for the $$ \mathcal{N} $$
N
= 2 tensor multiplet in harmonic superspace. The obtained results agree with those derived by applying the Batalin-Vilkovisky scheme within the harmonic superspace setting.
Hagedorn temperature in holography: world-sheet and effective approaches
Authors: Bigazzi Francesco , Canneti Tommaso , Castellani Federico , Cotrone Aldo L. , Mück Wolfgang 
Published: September 2024

Abstract
We provide general results on the Hagedorn temperature of planar, strongly coupled confining gauge theories holographically dual to type II superstring models on curved backgrounds with Ramond-Ramond and Kalb-Ramond fluxes and non-trivial dilaton. For exact backgrounds the Hagedorn temperature is determined up to next-to-next-to-next-to-leading order (NNNLO) in an expansion in α′; in all the other cases the results can be safely trusted up to NNLO. To reach these goals we exploit two complementary approaches. On the one hand, we perform an extrapolation to the Hagedorn regime of world-sheet results obtained from the semiclassical quantization of string configurations winding around the compact Euclidean time direction. En passant, we provide a detailed derivation of the fermionic part of the world-sheet spectrum, which is hard to find in the literature. On the other hand, we perturbatively solve the equations of motion for the thermal scalar field corresponding to the lightest mode of the winding string, which in flat space becomes tachyonic above the Hagedorn temperature. The interplay between different approaches is surely convenient, but we provide insights about a possible derivation of the whole NNLO correction to the Hagedorn temperature from a pure world-sheet perspective; furthermore, we determine the effective mass of the thermal scalar from the world-sheet in full generality.
Arbeitsplatzbezogenes Belastungserleben und psychische Gesundheit der Beschäftigten im Gesundheitswesen während der COVID-19-Pandemie: Risiko- und Schutzfaktoren aus der VOICE-Studie
Authors: Erim Yesim , Geiser Franziska , Beschoner Petra , Jerg-Bretzke Lucia , Weidner Kerstin , Albus Christian , Baranowski Andreas M. , Mogwitz Sabine , Morawa Eva 
Published: September 2024

Zusammenfassung
Hintergrund
Beschäftigte im Gesundheitswesen haben ein erhöhtes Risiko für Depressionen und Angstsymptome und insbesondere während der COVID-19-Pandemie war medizinisches Personal vielseitig gefordert. Ziel der VOICE-Studie war es, Risiko- und Schutzfaktoren für arbeitsplatzbezogenes Belastungserleben und psychische Gesundheit zu untersuchen.

Methode
Im Verbund von 5 psychosomatischen Universitätskliniken (Erlangen, Ulm, Bonn, Köln und Dresden) wurde ab Frühjahr 2020 eine multizentrische, webbasierte und prospektive Befragung (VOICE-Studie) initiiert. An der Studie nahmen zu 5 Messzeitpunkten mehr als 25.000 Personen teil.

Ergebnisse
Von 3678 während der ersten Pandemiewelle untersuchten Mitarbeitenden im Krankenhaussetting waren 17,4 % bzw. 17,8 % der Ärztinnen und Ärzte, 21,6 % bzw. 19,0 % der Pflegekräfte und 23,0 % bzw. 20,1 % der medizinisch-technischen Assistenteninnen und Assistenten (MTA) von Depressions- und Angstsymptomen in klinisch relevantem Ausmaß betroffen. Die wichtigsten Risikofaktoren für eine depressive bzw. Angstsymptomatik waren unzureichende Erholung in der Freizeit, erhöhter Alkoholkonsum, geringeres Vertrauen in die Kolleginnen und Kollegen in schwierigen Arbeitssituationen sowie erhöhte Angst, sich mit COVID-19 zu infizieren. Prädiktoren für eine erhöhte posttraumatische Symptomatik waren erhöhte generalisierte Angst und Depressivität sowie erhöhte Angst vor Ansteckung der Angehörigen. Als protektive Faktoren fungierten Kohärenzgefühl, soziale Unterstützung, Optimismus und Belohnungsniveau.

Diskussion
Die psychischen Auswirkungen arbeitsplatzbezogener Belastung in der Pandemie stellten sich als bedeutsam dar. Daher sind regelmäßige Screening- und Präventionsprogramme zur psychischen Gesundheit für Beschäftigte im Gesundheitswesen angezeigt.
Mortality rates in people presenting with a new diabetes-related foot ulcer: a cohort study with implications for management
Authors: Holman Naomi , Yelland Arthur C. , Young Bob , Valabhji Jonathan , Jeffcoate William , Game Fran 
Published: September 2024

Abstract
Aims/hypothesis
People with diabetes-related foot ulcers (DFUs) have high mortality rates. This analysis assesses the impact of selected risk factors on short-term mortality using a population registered in the National Diabetes Foot Care Audit (NDFA).

Methods
Mortality rates at 12, 26 and 52 weeks was assessed in people with a new DFU registered by a specialist diabetes footcare service in the NDFA in England and Wales between April 2017 and March 2022. Poisson regression models were created to explore risk factors for mortality.

Results
In 71,000 people registered with a new DFU, mortality rates at 12, 26 and 52 weeks was 4.2%, 8.2% and 14.4%, respectively. At 26 weeks, higher mortality rates was associated with older age (rate ratio 2.15; 95% CI 2.03, 2.28, for age ≥80 years vs age 65–79 years), certain ulcer characteristics (area ≥1 cm2 [1.50; 95% CI 1.42, 1.59], deep ulcers [1.26; 95% CI 1.18, 1.35] or hindfoot location [1.53; 95% CI 1.44, 1.62]) and recorded evidence of ischaemia in the lower limb (1.78; 95% CI 1.69, 1.88) and various comorbidities (heart failure [2.13; 95% CI 2.00, 2.26], myocardial infarction [1.45; 95% CI 1.29, 1.63], stroke [1.37; 95% CI 1.22, 1.53], renal replacement therapy [2.34; 95% CI 2.09, 2.61] and chronic kidney disease stage 3 or greater [1.20; 95% CI 1.12, 1.29]). The 26-week mortality rate exceeded 25% for 7.3% of all individuals, rising to 11.5% of those aged 65 years and older, and 22.1% of those aged 80 years and over.

Conclusions/interpretation
Short-term mortality rates in people with a DFU is high. Teams managing people with DFUs should consider modifying the burdensome interventions and care required to heal such ulcers so maximising the quality of residual life, rather than focusing exclusively on healing.

Graphical Abstract
Reconstruction of severe acetabular defects (Paprosky type III A) in total hip arthroplasty using modular tantalum augments in combination with a cemented cup
Authors: Spranz David , Müller Lisa-Marie , Trefzer Raphael , Hetto Pit , Nees Timo , Renkawitz Tobias , Walker Tilman , Reiner Tobias 
Published: September 2024

Abstract
Purpose
Acetabular defect reconstruction can be a complex and challenging surgical procedure, with stable long-term fixation of the implants remaining the ultimate goal. The purpose of this study was (1) to evaluate the radiological and clinical outcome of complex acetabular reconstruction surgery with the use of modular tantalum TM augments in combination with cemented revision cups; (2) to investigate blood tantalum concentrations in these patients; and (3) to report complications and mechanisms of failure related to this procedure at mid-term follow-up (mean 4.5 years).

Methods
We retrospectively reviewed 29 patients (29 hips) with severe acetabular bone loss (Paprosky type III A) reconstructed using a modular tantalum TM augment in combination with a cemented cup. We evaluated the implant survival and the radiological and clinical outcomes after a mean follow-up of 4.5 years (SD 2.2; range 8.4 – 2.1 years) using patient reported outcome scores (PROMs). Blood samples were analysed regarding tantalum concentration and compared with a control group.

Results
The cumulative survival rate at 4.5 years with the endpoint “revision of the acetabular component for any reason” was 96.2% (95% Confidence Interval 75.7–99.5). The PROMs improved significantly up to the latest follow-up, and radiographic data showed only one patient with signs of initial implant migration with a broken screw and a change of the position of the augment and the cup. Mean blood tantalum concentrations were significantly higher in the study group (0.16 µg/L) compared to the control group (0.002 µg/L) (P < 0.001).

Conclusions
This study has demonstrated good mid-term (mean 4.5 years) clinical and radiological outcomes of modular tantalum TM augments in combination with a cemented cup for the reconstruction of major acetabular defects. Mean blood tantalum concentrations were increased in patients with stable tantalum implants compared to healthy controls.
A statistical evaluation of the sexual dimorphism of the acetabulum in an Iberian population
Authors: Warrier Varsha , San-Millán Marta 
Published: September 2024

Abstract
Sex estimation is essential for human identification within bioarchaeological and medico-legal contexts. Amongst the sexually dimorphic skeletal elements commonly utilised for this purpose, the pelvis is usually preferred because of its direct relationship with reproduction. Furthermore, the posterior part of the innominate bone has proven to have better preservation within degraded contexts. With the aim of investigating the potential of the vertical acetabular diameter as a sex marker, 668 documented individuals from three different Iberian skeletal collections were randomly divided into training and test samples and eventually analysed using different statistical approaches. Two traditional (Discriminant Function Analysis and Logistic Regression Analysis) and four Machine learning methodologies (Support Vector Classification, Decision Tree Classification, k Nearest Neighbour Classification, and Neural Networks) were performed and compared. Amongst these statistical modalities, Machine Learning methodologies yielded better accuracy outcomes, with DTC garnering highest accuracy percentages of 83.59% and 89.85% with the sex-pooled and female samples, respectively. With males, ANN yielded highest accuracy percentage of 87.70%, when compared to other statistical approaches. Higher accuracy obtained with ML, along with its minimal statistical assumptions, warrant these approaches to be increasingly utilised for further investigations involving sex estimation and human identification. In this line, the creation of a statistical platform with easier user interface can render such robust statistical modalities accessible to researchers and practitioners, effectively maximising its practical use. Future investigations should attempt to achieve this goal, alongside examining the influence of factors such as age, on the obtained accuracy outcomes.
The plant early recombinosome: a high security complex to break DNA during meiosis
Authors: Rafiei Nahid , Ronceret Arnaud 
Published: September 2024

Abstract
Key message
The formacion of numerous unpredictable DNA Double Strand Breaks (DSBs) on chromosomes iniciates meiotic recombination. In this perspective, we propose a ‘multi-key lock’ model to secure the risky but necesary breaks as well as a ‘one per pair of cromatids’ model for the topoisomerase-like early recombinosome.

Abstract
During meiosis, homologous chromosomes recombine at few sites of crossing-overs (COs) to ensure correct segregation. The initiation of meiotic recombination involves the formation of DNA double strand breaks (DSBs) during prophase I. Too many DSBs are dangerous for genome integrity: if these DSBs are not properly repaired, it could potentially lead to chromosomal fragmentation. Too few DSBs are also problematic: if the obligate CO cannot form between bivalents, catastrophic unequal segregation of univalents lead to the formation of sterile aneuploid spores. Research on the regulation of the formation of these necessary but risky DSBs has recently advanced in yeast, mammals and plants. DNA DSBs are created by the enzymatic activity of the early recombinosome, a topoisomerase-like complex containing SPO11. This opinion paper reviews recent insights on the regulation of the SPO11 cofactors necessary for the introduction of temporally and spatially controlled DSBs. We propose that a ‘multi-key-lock’ model for each subunit of the early recombinosome complex is required to secure the formation of DSBs. We also discuss the hypothetical implications that the established topoisomerase-like nature of the SPO11 core-complex can have in creating DSB in only one of the two replicated chromatids of early prophase I meiotic chromosomes. This hypothetical ‘one per pair of chromatids’ DSB formation model could optimize the faithful repair of the self-inflicted DSBs. Each DSB could use three potential intact homologous DNA sequences as repair template: one from the sister chromatid and the two others from the homologous chromosomes.
Polymorphisms in the genes encoding RLR and TLR3 and CMV DNAemia in subjects coinfected with human immunodeficiency virus and cytomegalovirus
Authors: Jabłońska Agnieszka , Jabłonowska Elżbieta , Studzińska Mirosława , Kamerys Juliusz , Paradowska Edyta 
Published: September 2024

AbstractCytomegalovirus (CMV) is a pathogen that is common worldwide and is often present in individuals infected with human immunodeficiency virus (HIV). Pattern recognition receptors (PRRs) are host sensors that activate the immune response against infectious agents. However, it is unclear whether PRR single-nucleotide polymorphisms (SNPs) are associated with the occurrence of CMV DNAemia in subjects coinfected with HIV and CMV. HIV/CMV-coinfected patients with and without CMV DNAemia were recruited for this study. The DDX58 rs10813831 and IFIH1 (rs3747517 and rs1990760) polymorphisms were genotyped using the TaqMan Allelic Discrimination Assay, whereas the DDX58 rs12006123 and TLR3 (rs3775291 and rs3775296) SNPs were analyzed using a polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) assay. A mutation present in at least one allele of the DDX58 rs12006123 SNP occurred at least two times more frequently in HIV/CMV-coinfected patients with CMV DNAemia than in coinfected subjects without CMV DNAemia (OR, 2.50; 95% CI, 1.33–4.68; p = 0.004, in the dominant model). A higher level of CMV DNAemia was observed in subjects who had the heterozygous (GA) or homozygous recessive (AA) genotype for the DDX58 rs12006123 SNP compared with those who had the wild-type (GG) genotype (p = 0.0003). Moreover, in subjects with a mutation detected in at least one allele of the DDX58 rs12006123 SNP, a lower serum IFN-β concentration was found compared with those who had a wild-type (GG) genotype for this polymorphism (p = 0.024). The DDX58 rs12006123 SNP is associated with CMV DNAemia in HIV/CMV-coinfected patients.
Pseudo-outbreak of Bacillaceae species associated with poor compliance with blood culture collection recommendations
Authors: Borcan Alina Maria , Vasile Carmen-Cristina , Popa Alina-Ioana , Badea Cristina Andreea , Popescu Gabriel Adrian , Tălăpan Daniela 
Published: September 2024

Abstract
Purpose
This study describes a pseudo-outbreak of Bacillaceae spp. bloodstream infections that spanned five months starting in May 2023 and the infection prevention measures implemented to control it.

Methods
This retrospective study was conducted at a tertiary infectious disease hospital in Bucharest, Romania. An observational audit of the blood culture collection practice in our hospital was performed, and the materials used during blood culture collection were sampled. Bacterial colonies were identified using MALDI Biotyper. The Bacillaceae blood culture positivity rates in the previous four years were compared using the Kruskal‒Wallis rank test.

Results
Bacillaceae spp.-positive blood cultures were recovered from 60 patients over a five-month period. In the case of 58 patients, Bacillaceae spp.-positive blood cultures were considered contaminated. Two patients were treated for Bacillus spp. bacteraemia. The audit revealed significant variation during the preparation of the venipuncture site step and the use of nonsterile medical cotton wool. Medical cotton wool contaminated with species of Bacillaceae was found in 10 out of 12 wards. The control measures included repeated training on the blood culture collection procedure and the removal of Bacillaceae spp.-contaminated cotton wool.

Conclusions
The pseudo-outbreak was caused by the unjustified use of medical cotton wool for disinfection of the skin and blood culture bottle septums. The investigation of this pseudo-outbreak highlighted a gap in blood culture collection practices at our facility and thus allowed for its improvement.
Ireland’s Mental Health Bill 2024: progress, problems and Procrustean perils
Authors: Kelly Brendan D. 
Published: September 2024

Abstract
Background
Ireland’s Mental Health Bill 2024 proposes the most significant revision of mental health legislation since the Mental Health Act 2001.

Aims
To explore the 2024 Bill and provide suggestions for the subsequent Act.

Methods
Review of the 2024 Bill and related literature.

Results
The 2024 Bill proposes useful new definitions (e.g., ‘mental disorder’, ‘treatment’) and provisions governing specific practices (e.g., ‘physical restraint’). Revision is needed to better provide care and protect rights: (a) proposed treatment criteria for involuntary admission should be retained, but ‘risk’ criteria deleted; (b) treatment provisions should ensure mental health legislation provides for timely, accountable treatment for all patients; (c) detailed provisions about the content of treatment plans do not belong in primary legislation, which is ill-suited to micro-managing individual care and (d) the Mental Health Commission should be incorporated into the Health Information and Quality Authority.

Conclusions
The 2024 Bill proposes useful changes but requires revision, especially for involuntary patients who lack decision-making capacity and decline care, for whom the Assisted Decision-Making (Capacity) Act 2015 does not (and was not designed to) provide solutions. Relying on a convoluted combination of the 2015 Act, Circuit Court and High Court would be legally impossible, clinically impracticable and de facto denial of the rights of people with serious mental illness and their families. The final Act can accord with principles of the 2015 Act without relying on its provisions and should benefit patients and support staff in delivering mental health care that is essential and often life-saving.
Effect of stabilized organic amendments on biodegradability of poly-3-hydroxybutyrate, soil biological properties, and plant biomass
Authors: Brtnicky M. , Holatko J. , Hammerschmiedt T. , Mustafa A. , Kamenikova E. , Kintl A. , Radziemska M. , Baltazar T. , Malicek O. , Kucerik J. 
Published: September 2024

AbstractPoly-3-hydroxybutyrate (P3HB) is a biodegradable polymer with a potential extensive use in agriculture. However, while P3HB biodegradation boosts microbial enzyme activity, it significantly reduces plant biomass due to nutrient competition. In this study, we test the hypothesis that these detrimental effects can be mitigated though the co-application of nutrient-rich organic amendments, such as compost and digestate. A pot experiment with lettuce (Lactuca sativa), grown in soil amended with P3HB lone or combined with either compost or digestate. Six variants were tested: Control, Compost, Compost + P3HB, Digestate, Digestate + P3HB, and P3HB alone. We evaluated degradation of the P3HB polymer, biological soil properties, and both the dry and fresh biomass of the lettuce. We observed that adding P3HB alone enhanced dehydrogenase and urease activities, as well as all types of respiration, except for L-arginine-induced respiration. However, it strongly and negatively affected the biomass of lettuce (both aboveground and root). The strong adverse effects of P3HB on plant growth were also observed when compost was co-applied, although this combination enhanced all enzyme activities except for suppressed β-glucosidase. Conversely, co-applying digestate with P3HB alleviated the negative effect of P3HB on both the dry and fresh biomass together lettuce. Additionally, this combination increased the activity of several enzymes (dehydrogenase, arylsulfatase, N-acetyl-β-D-glucosaminidase, urease), and enhanced all types of respiration, except for L-arginine-induced respiration. The use of biodegradable plastics in agriculture is on rise, but it may be compromised, because their biodegradation my negatively impact plant growth. The results showed that co-application of digestate is an effective solution to alleviate these effects, while co-application of compost failed. Generally, organic amendments seem to be an option to alleviate the negative effects of bioplastics biodegradation, and offers options how to handle the treatment of waste bioplastics or their residues, but further investigation is needed to understand the underlaying mechanisms involved.
Graphical Abstract
Multiple Tin Compounds Modified Carbon Fibers to Construct Heterogeneous Interfaces for Corrosion Prevention and Electromagnetic Wave Absorption
Authors: Guo Zhiqiang , Lan Di , Jia Zirui , Gao Zhenguo , Shi Xuetao , He Mukun , Guo Hua , Wu Guanglei , Yin Pengfei 
Published: September 2024

AbstractCurrently, the demand for electromagnetic wave (EMW) absorbing materials with specific functions and capable of withstanding harsh environments is becoming increasingly urgent. Multi-component interface engineering is considered an effective means to achieve high-efficiency EMW absorption. However, interface modulation engineering has not been fully discussed and has great potential in the field of EMW absorption. In this study, multi-component tin compound fiber composites based on carbon fiber (CF) substrate were prepared by electrospinning, hydrothermal synthesis, and high-temperature thermal reduction. By utilizing the different properties of different substances, rich heterogeneous interfaces are constructed. This effectively promotes charge transfer and enhances interfacial polarization and conduction loss. The prepared SnS/SnS2/SnO2/CF composites with abundant heterogeneous interfaces have and exhibit excellent EMW absorption properties at a loading of 50 wt% in epoxy resin. The minimum reflection loss (RL) is − 46.74 dB and the maximum effective absorption bandwidth is 5.28 GHz. Moreover, SnS/SnS2/SnO2/CF epoxy composite coatings exhibited long-term corrosion resistance on Q235 steel surfaces. Therefore, this study provides an effective strategy for the design of high-efficiency EMW absorbing materials in complex and harsh environments.