bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inclusion in the clinic: A mixed methods study of left‐handed student's perceptions of using cordless keyboards
Authors: Adams Danita , Fulkerson Dikuua Kelly Jo , Hall Amy 
Published: September 2024

AbstractPurpose/objectivesLittle is written on obstacles for left‐handed students in the dental clinic. This mixed methods study evaluates the experiences of using cordless keyboards for left‐handed dental students.MethodsResearchers purchased four Logitech K400 Plus wireless keyboards. Using Qualtrics, a survey software, a pre‐survey was sent out at the beginning of the spring semester prior to introducing the cordless keyboards. A post‐survey circulated at the end of the semester. Quantitative analysis statistical analysis was conducted using IBM SPSS Statistics. Researchers conducted a thematic analysis of the qualitative survey responses.ResultsTwenty‐three left‐handed D3 and D4 dental students were asked to participate in a survey about cordless keyboards. The pre‐survey had a 100% response rate, and the post‐survey had a 71% response rate. The surveys indicated that left‐handed students often face a range of barriers in clinical settings, including ergonomic challenges to enter data, difficulty managing time due to double entry of data on right‐handed equipment, and feelings of psychological unsafety due to fear for asking for support. The most significant finding was as follows: not only did the cordless keyboard assist clinical performance, but the cordless keyboard project also helped students feel heard and validated as left‐handed learners.ConclusionsResearchers recommend that educators prioritize the inclusion of left‐handed learners through various practices like making adjustments to physical spaces and creating inclusive environments where all learners feel supported.
A pilot study: Examining cytoskeleton gene expression profiles in Pakistani children with autism spectrum disorder
Authors: Malik Sana , Ali Syed Aoun , Mehdi Ahmed Murtaza , Raza Amir , Bashir Shahid , Baig Deeba Noreen 
Published: September 2024

AbstractBackgroundFinding effective pharmacological interventions to address the complex array of neurodevelopmental disorders is currently an urgent imperative within the scientific community as these conditions present significant challenges for patients and their families, often impacting cognitive, emotional, and social development. In this study, we aimed to explore non‐invasive method to diagnose autism spectrum disorders (ASD) within Pakistan children population and to identify clinical drugs for its treatment.AimsThe current report outlines a comprehensive bidirectional investigation showcasing the successful utilization of saliva samples to quantify the expression patterns of profilins (PFN1, 2, and 3); and ERM (ezrin, radixin, and moesin) proteins; and additionally moesin pseudogene 1 and moesin pseudogene 1 antisense (MSNP1AS). Subsequently, these expression profiles were employed to forecast interactions between drugs and genes in children diagnosed with ASD.MethodsThis study sought to delve into the intricate gene expression profiles using qualitative polymerase chain reaction of profilin isoforms (PFN1, 2, and 3) and ERM genes extracted from saliva samples obtained from children diagnosed with ASD. Through this analysis, we aimed to elucidate potential molecular mechanisms underlying ASD pathogenesis, shedding light on novel biomarkers and therapeutic targets for this complex neurological condition. (n = 22). Subsequently, we implemented a diagnostic model utilizing sparse partial least squares discriminant analysis (sPLS‐DA) to predict drugs against our genes of interest. Furthermore, connectivity maps were developed to illustrate the predicted associations of 24 drugs with the genes expression.ResultsOur study results showed varied expression profile of cytoskeleton linked genes. Similarly, sPLS‐DA model precisely predicted drug to genes response. Sixteen of the examined drugs had significant positive correlations with the expression of the targeted genes whereas eight of the predicted drugs had shown negative correlations.ConclusionHere we report the role of cytoskeleton linked genes (PFN and ERM) in co‐relation to ASD. Furthermore, variable yet significant quantitative expression of these genes successfully predicted drug–gene interactions as shown with the help of connectivity maps that can be used to support the clinical use of these drugs to treat individuals with ASD in future studies.
Breaking small automorphisms by list colourings
Authors: Kwaśny Jakub , Stawiski Marcin 
Published: September 2024

AbstractFor a graph , we define a small automorphism as one that maps some vertex into its neighbour. We investigate the edge colourings of that break every small automorphism of . We show that such a colouring can be chosen from any set of lists of length 3. In addition, we show that any set of lists of length 2 on both edges and vertices of yields a total colouring which breaks all the small automorphisms of . These results are sharp, and they match the known bounds for the nonlist variant.
Discovery of Structural Diversity Guided N‐S Heterocyclic Derivatives Based on Natural Benzothiazole Alkaloids as Potential Cytotoxic Agents
Authors: Guo Lirong , Wan Yafei , Liu Manli , Zheng Fuqiang , Shi Yingwu , Wang Kaimei , Cao Xiufang , Bao Longzhu , Ke Shaoyong 
Published: September 2024

ABSTRACTBenzothiazole alkaloids are a class of rare heterocyclic alkaloids with unique structures and exhibit a wide range of biological activities. So, the aim of this work is to investigate structural diversity‐guided N‐S heterocyclic derivatives based on natural benzothiazole alkaloids as potential cytotoxic agents. Three series of novel benzothiazole derivatives, including 22 compounds, were designed and synthesized using pharmacophore hybridization, and their in vitro cytotoxic activities against Huh‐7 and A875 were fully evaluated. The results indicated that some of these benzothiazole derivatives had significantly good cytotoxic activities against two tested cell lines compared with the positive control 5‐fluorouracil, and other compounds 3f–3i displayed good selectivity between A875 and Huh‐7 cell lines, which might be used as promising lead molecule for discovery of novel benzothiazole‐type cytotoxic agents.
Study and optimising performance of enhancement‐mode monolithically integrated white‐light HEMT‐LED by inserting of InGaN quantum wells
Authors: Bhattacharjee Hindol , Dey Anup , Meher Preetisudha 
Published: September 2024

AbstractIn this paper five enhancement‐mode monolithically integrated white‐light High electron mobility transistors‐light emitting diodes (HEMT‐LED) structures are proposed and simulated to obtain maximum light intensity, drain current Id and maximum trans‐conductance gm. In first four HEMT‐LED structures white light is generated by combining inbuilt yellow and blue lights and in fifth proposed structure the white light is generated with the combination of inbuilt red, green and blue lights. The InGaN quantum wells (QWs) are inserted in to e‐mode ITO/p‐GaN gate HEMT structures and the desired wavelength of light spectrums are generated by changing the in content (mole fraction), to obtain inbuilt white light. Among five proposed structures one shows Maximum Id‐max of 925 mA and maximum gm of 250 mS, which is significantly higher than any HEMT‐LED structures reported before. All the proposed structures are simulated in Silvaco TCAD software.
Why Is Generation Z Motivated at Work? A Qualitative Exploration
Authors: Dwivedula Ravikiran 
Published: September 2024

ABSTRACTThis article aims to identify and explain the factors leading to work motivation among the Generation Z workforce, using the self‐determination theory (SDT) of motivation as a lens. The study involved 317 respondents and utilized open‐ended questions to gather textual responses through a survey. The responses were analyzed using NVIVO 14. Seven broad themes explained this cohort's work motivation: nature of work, job, support, future opportunities, references, experience, and career. The two most autonomous forms of motivation—intrinsic motivation and identified regulation—significantly explain worker motivation. Theoretically, the study's findings advance the SDT of motivation by applying its principles to an emerging workforce. Additionally, these findings enhance our comprehension of Generation Z workers’ motivation across various industries. From a managerial perspective, the results may inform the development of targeted human resource practices aimed at motivating Generation Z employees within organizations.
Fe toxicity tolerance is advantageous in rice growth recovery after Fe stress alleviation
Authors: Fujimoto Riku , Aratani Haruka , Rumanti Indrastuti A. , Nugraha Yudhistira , Kamiya Takehiro , Yamasaki Yuji , Kato Yoichiro 
Published: September 2024

AbstractBackgroundFe toxicity often inhibits rice growth on acid sulfate soils in tropical coastal lowlands. Previous studies in plant physiology and breeding have focused on high‐Fe stress, but not on growth recovery after stress alleviation.AimsThe objective of this study was to elucidate the morphophysiological characteristics in rice growth recovery from high‐Fe stress.MethodsWe evaluated the seedling growths of Taichung65 (T65) (Fe toxicity‐tolerant) and Ciherang (susceptible) in hydroponic culture, during the period of high‐Fe stress (250 mg Fe2+ L−1 for 12 or 18 days) and after stress alleviation.ResultsThe plant growth rate during recovery was negatively correlated with the leaf bronzing score (damage symptoms due to Fe toxicity) at the end of high‐Fe stress, which in turn was negatively correlated with the shoot Fe concentration. After 18‐day stress, T65 showed greater growth recovery than Ciherang, attributable to its higher net assimilation rate, higher transpiration rate (water uptake/green leaf area), and greater increase in total root length during recovery. In particular, T65 showed vigorous lateral root development in nodal roots that emerged during the stress period and vigorous growth of nodal roots that emerged during recovery.ConclusionsOur results suggest that tolerance to high‐Fe stress confers an advantage in growth recovery. It is likely that tolerance to Fe toxicity contributes not only to the maintenance of green leaf area at the end of stress but also to quick root growth recovery, leading to vigorous water uptake and high photoassimilation capacity after stress alleviation.
Unraveling social undermining at the workplace: A systematic review of past achievements and future promises
Authors: Haider Bilal , Khizar Hafiz Muhammad Usman , Kallmuenzer Andreas , Hilal Omnia Abdelazeem 
Published: September 2024

AbstractIn the contemporary landscape of organizational dynamics, it is imperative to understand the nuance of social undermining behaviors in the workplace for effective strategy and decision‐making. In this regard, this study reviews, identifies, and critically evaluates the social undermining literature and offers new avenues for future research. The systematic literature review methodology has been used to select and critically review 65 studies on this topic. The analysis and findings of this review are presented in three sections, as follows, (i) research profiling—to highlight the current status of research on social undermining in management literature, (ii) literature synthesis—to highlight key theories and conceptions of social undermining as well as discuss the antecedents and outcomes of social undermining, and (iii) critical analysis—to highlight knowledge gaps in existing research and set future agenda. This review is the first comprehensive review on social undermining at the workplace and serves as a knowledge base by presenting a comprehensive literature review as well as extending further development of knowledge on this topic. A key contribution of our review is the proposal of a comprehensive framework of literature synthesis to provide a bird's eye view on this scholarly domain. Our study contributes to organizational behavior and strategic management discourse by offering crucial insights on human dynamics that shape organizational strategy, and change.
Factors Associated With Prolonged Operative Times in Laparoscopic Right Hemicolectomy and Its Association With Short‐Term Outcomes
Authors: Emile Sameh Hany , Horesh Nir , Garoufalia Zoe , Gefen Rachel , Dourado Justin , Dasilva Giovanna , Wexner Steven D. 
Published: September 2024

ABSTRACTBackgroundThis study aimed to investigate factors associated with prolonged operative time in laparoscopic right hemicolectomy for colon cancer.MethodsThis was a retrospective review of patients with colon cancer who underwent laparoscopic right hemicolectomy between 2011 and 2021. Linear and binary logistic regression analyses were performed to determine factors associated with prolonged operative time. The association between longer operative times and complications and hospital stay was assessed.ResultsOne hundred and ninety‐seven patients (52.3% female; mean age: 68.8 ± 14.1 years) were included. Factors independently associated with operative time were male sex (β = 17.3, 95% CI: 2, 32.5; p = 0.026) and extended hemicolectomy (β = 67.7, 95% CI: 27.6, 107.9; p = 0.001). American Society of Anesthesiologists (ASA) IV classification had a borderline significant association with operative time (β = 100.4, 95% CI: −2.05, 202.9; p = 0.055). Male sex (r = 0.158; p = 0.026), body mass index (r = 0.205; p = 0.004), ASA classification (r = 0.232; p = 0.001), extended hemicolectomy (r = 0.256; p < 0.001), and intracorporeal vessel control (r = 0.161; p = 0.025) had significant positive correlation with operative times. Patients with operative times ≥ 160 min had significantly longer hospital stays (5 vs. 4 days; p = 0.043) and similar complication rates to patients with shorter operative times.ConclusionsMale sex, advanced ASA classification, and extended hemicolectomy were independently and significantly associated with longer operative times in laparoscopic right hemicolectomy. Longer operative times were associated with longer hospital stays and similar complication rates.
Review of 2022 PSOGI/RENAPE Consensus on HIPEC
Authors: Kusamura Shigeki , Bhatt Aditi , van Der Speeten Kurt , Kepenekian Vahan , Hübner Martin , Eveno Clarisse , de Hingh Ignace , Delhorme Jean‐Baptiste , Taibi Abdelkader , Villeneuve Laurent , Dico Rea Lo , Moran Brendan , Govaerts Kim , Zivanovic Oliver , Brennan Donal , Nadeau Cedric , Van Driel Willemien , Bakrin Naoual , Piso Pompiliu , Verwaal Victor J. , González‐Moreno Santiago , Alyami Mohammad , Sgarbura Olivia , Rau Beate , Deraco Marcello , Glehen Olivier 
Published: September 2024

ABSTRACTThe 2022 PSOGI (Peritoneal Surface Oncology Group International) and RENAPE (French Network for Rare Peritoneal Malignancies) consensus on hyperthermic intraperitoneal chemotherapy (HIPEC) was a comprehensive effort aimed at standardizing treatment protocols for various peritoneal malignancies. This initiative is critical due to the wide range of technical variations in HIPEC procedures and the resulting need for standardization to ensure consistent and effective patient care and meaningful audit of multicenter data.
Development and Validation of a Predictive Risk Score for Blood Transfusion in Patients Undergoing Curative‐Intent Surgery for Intrahepatic Cholangiocarcinoma
Authors: Catalano Giovanni , Alaimo Laura , Endo Yutaka , Chatzipanagiotou Odysseas P. , Ruzzenente Andrea , Aldrighetti Luca , Weiss Matthew , Bauer Todd W. , Alexandrescu Sorin , Poultsides George A. , Maithel Shishir K. , Marques Hugo P. , Martel Guillaume , Pulitano Carlo , Shen Feng , Cauchy François , Koerkamp Bas G. , Endo Itaru , Kitago Minoru , Pawlik Timothy M. 
Published: September 2024

ABSTRACTBackground and ObjectivesAmong patients undergoing liver resection for intrahepatic cholangiocarcinoma (ICC), perioperative bleeding requiring blood transfusion is a common complication, yet preoperative identification of patients at risk for transfusion remains challenging. The objective of this study was to develop a preoperative risk score for blood transfusion requirement during surgery for ICC.MethodsPatients undergoing curative‐intent liver surgery for ICC (1990–2020) were identified from a multi‐institutional database. A predictive model was developed and validated. An easy‐to‐use risk calculator was made available online.ResultsAmong 1420 patients, 300 (21.1%) received an intraoperative transfusion. Independent predictors of transfusion included severe preoperative anemia (OR = 1.65, 95% CI 1.10–2.47), T2 category or higher (OR = 2.00, 95% CI 1.36–3.02), positive lymph nodes (OR = 1.75, 95% CI 1.32–2.32) and major resection (OR = 2.56, 95%CI 1.85–3.58). Receipt of blood transfusion significantly correlated with worse outcomes. The model showed good discriminative ability in both training (AUC = 0.68, 95% CI 0.66–0.72) and bootstrapping validation (C‐index = 0.67, 95% CI 0.65–0.70) cohorts. An online risk calculator of blood transfusion requirement was developed (https://catalano-giovanni.shinyapps.io/TransfusionRisk).ConclusionsIntraoperative blood transfusion was significantly associated with poor postoperative outcomes among patients undergoing surgery for ICC. The identification of patients at high risk of transfusion could improve perioperative patient care and blood resources allocation.
Deep learning‐based structure segmentation and intramuscular fat annotation on lumbar magnetic resonance imaging
Authors: Xu Yefu , Zheng Shijie , Tian Qingyi , Kou Zhuoyan , Li Wenqing , Xie Xinhui , Wu Xiaotao 
Published: September 2024

AbstractBackgroundLumbar disc herniation (LDH) is a prevalent cause of low back pain. LDH patients commonly experience paraspinal muscle atrophy and fatty infiltration (FI), which further exacerbates the symptoms of low back pain. Magnetic resonance imaging (MRI) is crucial for assessing paraspinal muscle condition. Our study aims to develop a dual‐model for automated muscle segmentation and FI annotation on MRI, assisting clinicians evaluate LDH conditions comprehensively.MethodsThe study retrospectively collected data diagnosed with LDH from December 2020 to May 2022. The dataset was split into a 7:3 ratio for training and testing, with an external test set prepared to validate model generalizability. The model's performance was evaluated using average precision (AP), recall and F1 score. The consistency was assessed using the Dice similarity coefficient (DSC) and Cohen's Kappa. The mean absolute percentage error (MAPE) was calculated to assess the error of the model measurements of relative cross‐sectional area (rCSA) and FI. Calculate the MAPE of FI measured by threshold algorithms to compare with the model.ResultsA total of 417 patients being evaluated, comprising 216 males and 201 females, with a mean age of 49 ± 15 years. In the internal test set, the muscle segmentation model achieved an overall DSC of 0.92 ± 0.10, recall of 92.60%, and AP of 0.98. The fat annotation model attained a recall of 91.30%, F1 Score of 0.82, and Cohen's Kappa of 0.76. However, there was a decrease on the external test set. For rCSA measurements, except for longissimus (10.89%), the MAPE of other muscles was less than 10%. When comparing the errors of FI for each paraspinal muscle, the MAPE of the model was lower than that of the threshold algorithm.ConclusionThe models demonstrate outstanding performance, with lower error in FI measurement compared to thresholding algorithms.
The predictive association between social support, communal mastery, and response to culturally adapted cognitive processing therapy among Native American women
Authors: van Stolk‐Cooke Katherine , Brier Zoe M. F. , Pearson Cynthia , Price Matthew , Kaysen Debra 
Published: September 2024

AbstractThough social support (SS) and communal mastery (CM) are resilience factors among American Indian and Alaska Natives (AIAN), they have not been examined as trauma treatment predictors in this at‐risk group. This study evaluated whether SS and CM were associated with improved treatment response in a sample of 73 AIAN women with posttraumatic stress disorder (PTSD) symptoms. Participants received culturally adapted CPT and were assessed for PTSD, CM, and SS. Data were analyzed using linear mixed‐effects models. SS predicted improved PTSD, β = −.16, SE = .05, p = .003, and mental health, β = .16, SE = .05, p = .005, but not physical health. CM predicted improved PTSD, β = −.93, SE = .34, p = .008; mental health, β = .90, SE = .36, p = .013; and physical health, β = .95, SE = .31, p = .003. In a combined model, SS predicted improvements in PTSD, β = −.15, SE = .04, p < .001, and mental health, β = .12, SE = .06, p = .037, whereas CM did not. CM predicted improved physical health, β = 1.04, SE = .33, p = .003, whereas SS did not. Results highlight the benefits of SS and CM in trauma treatment outcomes for AIAN women, consistent with prior work, and further underscore the differential role of SS versus CM on mental versus physical health. Future work should explore how orientation to close and communal‐level relationships may inform the protective benefits of social resources among AIAN.
Status of peer review guidelines in international surgical journals: A cross‐sectional survey
Authors: Dong Min , Wang Wenjing , Liu Xuemei , Lei Fang , Luo Yunmei 
Published: September 2024

AbstractAimTo gain insight into the current status of peer review guidelines in international surgical journals and to offer guidance for the development of peer review guidelines for surgical journals.MethodsWe selected the top 100 journals in the category of ‘Surgery’ according to the Journal Citation Report 2021. We conducted a search of the websites of these journals, and Web of Science, PubMed, other databases, in order to gather the peer review guidelines published by these top 100 journals up until June 30, 2022. Additionally, we analysed the contents of these peer review guidelines.ResultsOnly 52% (52/100) of journals provided guidelines for reviewers. Sixteen peer review guidelines which were published by these 52 surgical journals were included in this study. The contents of these peer review guidelines were classified into 33 items. The most common item was research methodology, which was mentioned by 13 journals (25%, 13/52). Other important items include statistical methodology, mentioned by 11 journals (21.2%), the rationality of figures, tables, and data, mentioned by 11 journals (21.2%), innovation of research, mentioned by nine journals (17.3%), and language expression, readability of papers, ethical review, references, and so forth, mentioned by eight journals (15.4%). Two journals described items for quality assessment of peer review. Forty‐three journals offered a checklist to guide reviewers on how to write a review report. Some surgical journals developed peer review guidelines for reviewers with different academic levels, such as professional reviewers and patient/public reviewers. Additionally, some surgical journals provided specific items for different types of papers, such as original articles, reviews, surgical videos, surgical database research, surgery‐related outcome measurements, and case reports in their peer review guidelines.ConclusionsKey contents of peer review guidelines for the reviewers of surgical journals not only include items relating to reviewing research methodology, statistical methods, figures, tables and data, research innovation, ethical review, but also cover items concerning reviewing surgical videos, surgical database research, surgery‐related outcome measurements, instructions on how to write a review report, and guidelines on how to assess quality of peer review.