bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fecal gelatinase does not predict mortality in patients with alcohol-associated hepatitis
Authors: Yang Yongqiang , Hartmann Phillipp , Schnabl Bernd 
Published: October 2024

Abstract
Alcohol-associated liver disease is highly prevalent worldwide, with alcohol-associated hepatitis as a severe form characterized by substantial morbidity, mortality, and economic burden. Gut bacterial dysbiosis has been linked to progression of alcohol-associated hepatitis. Fecal cytolysin secreted by the pathobiont Enterococcus faecalis (E. faecalis) is associated with increased mortality in patients with alcohol-associated hepatitis. Although gelatinase is considered a virulence factor in E. faecalis, its prevalence and impact on alcohol-associated hepatitis patient outcomes remains unclear. In this study, 20 out of 65 (30.8%) patients with alcohol-associated hepatitis tested positive for gelatinase in their stool. There were no significant differences in 30-day and 90-day mortality between gelatinase-positive and gelatinase-negative patients (p=0.97 and p=0.48, respectively). Fecal gelatinase had a low discriminative ability for 30-day mortality (area under the curve [AUC] 0.50 vs fibrosis-4 Index (FIB-4) 0.75) and 90-day mortality compared with other established liver disease markers (AUC 0.57 vs FIB-4 0.79 or ‘age, serum bilirubin, INR, and serum creatinine’ (ABIC) score 0.78). Furthermore, fecal gelatinase was not an important feature for 30-day or 90-day mortality per random forest analysis. Finally, gelatinase-positive patients with alcohol-associated hepatitis did not exhibit more severe liver disease compared with gelatinase-negative patients. In conclusion, fecal gelatinase does not predict mortality or disease severity in patients with alcohol-associated hepatitis from our cohort.
FUNÇÕES DE PEDOTRANSFERÊNCIA PARA PREDIÇÃO DE ATRIBUTOS FÍSICO-HÍDRICOS DE SOLOS DO PIAUÍ, BRASIL
Authors: Ramos Herbert Moraes Moreira , Souza Valladares Gustavo , Edinaldo Pinto Mousinho Francisco , Soares Andrade Junior Aderson , Silva de Sousa Ricardo 
Published: October 2024

FUNÇÕES DE PEDOTRANSFERÊNCIA PARA PREDIÇÃO DE ATRIBUTOS FÍSICO-HÍDRICOS DE SOLOS DO PIAUÍ, BRASIL*

HERBERT MORAES MOREIRA RAMOS1; GUSTAVO SOUZA VALLADARES2; FRANCISCO EDINALDO PINTO MOUSINHO3; ADERSON SOARES ANDRADE JUNIOR4 E RICARDO SILVA DE SOUSA5

1Doutorando pelo Programa de Pós-graduação em Agronomia (PPGA) da Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portela, Bairro Ininga CEP: 64049-550 – Teresina, Piauí, Brasil, e-mail: moreiraramoss@hotmail.com
2Departamento de Geografia, Universidade Federal do Piauí (UFPI), Campus Universitário Ministro Petrônio Portela, Bairro Ininga CEP: 64049-550 – Teresina, Piauí, Brasil, e-mail: valladares@ufpi.edu.br
3Colégio Técnico de Teresina, Universidade Federal do Piauí, Campus Universitário Ministro Petrônio Portela, Bairro Ininga CEP: 64049-550 – Teresina, Piauí, Brasil, e-mail: fepmousi@ufpi.edu.br
4Embrapa Meio-Norte, Av. Duque de Caxias, n.º 5.650, Bairro Buenos Aires, CEP: 64008-780 – Teresina, Piauí, Brasil, e-mail: aderson.andrade@embrapa.br
5Departamento de Engenharia Agrícola e Solos, Universidade Federal do Piauí (UFPI), Campus Universitário Ministro Petrônio Portela, Bairro Ininga CEP: 64049-550 – Teresina, Piauí, Brasil, e-mail: ricardoss@ufpi.edu.br
* Trabalho proveniente de parte da tese de doutorado do primeiro autor, apresentada ao Programa de Pós-graduação em Agronomia (PPGA), da Universidade Federal do Piauí, UFPI, Teresina, Piauí, Brasil

1 RESUMO

RAMOS, H. M. M.; VALLADARES, G. S.; MOUSINHO, F. E. P.; ANDRADE JUNIOR, A. S. E SOUSA, R. S. DE
PEDOTRANSFERFUNCTIONS FOR PREDICTING PHYSICO-HYDRIC ATTRIBUTES OF SOILS IN PIAUÍ, BRAZIL
2 ABSTRACT

Keywords: pedometry, multiple linear regression, soil water.
A New Method for Feeding Laboratory-Reared Aedes aegypti (Diptera: Culicidae) Adult Females1
Authors: Morales-Hernández Filemón , Rodríguez-Maciel J. Concepción , Pardo-Melgarejo Saul , Ramírez-Becerril Valeria , Meraz-Maldonado Nora , Aguilar-Garzón Bismarck 
Published: October 2024

Abstract
The mosquito Aedes aegypti (L.) (Diptera: Culicidae) transmits arboviruses including the causative agent for yellow fever and threatens human health in tropical and subtropical areas. To reduce the incidence of infection, a variety of tactics is being developed to keep the population density of this vector mosquito as low as possible. Laboratory research directed to this end requires maintaining laboratory colonies of the insect, which, in this case, requires providing immobilized live animals to A. aegypti adult females for a source of blood for production of viable eggs. Using live animals for this procedure is costly, time consuming, and requires rearing mammalian species in the laboratoy. This study evaluated the impact of supplying the adult females with blood from a domestic pig (Sus scrofa domestica L.) mixed with an anticoagulant (7 ml of heparin per liter of blood) on the oviposition rate of A. aegypti. Feeding A. aegypti females with pig blood obtained from a slaughter facility and mixed with heparin produced more eggs (6,994 ± 168) than those allowed to feed on a living hamster as a source of blood (5,483 ± 171). Thus, this methodology is more efficient and economical than the current use of live animals to feed females of A. aegypti.
Complex signals parameters optimization on the base of linear approximations using the gradient method and Newton’s method
Authors: Комар Олексій Миколайович , Лисечко Володимир Петрович , Таршин Володимир Анатолійович , Місюра Олег Миколайович , Безверхий Сергій Анатолійович 
Published: October 2024

The article examines the effectiveness of the gradient descent and Newton methods for optimizing the parameters of ensembles of complex signals. Algorithms have been developed and implemented that increase the accuracy of setting parameters and ensure reasonable optimization of spectral, temporal and statistical characteristics of signals. The effectiveness of the application of the methods was confirmed experimentally on the example of reducing the error and increasing the level of immunity. The obtained results substantiate the improvement of the parameters of complex signals, which proves the efficiency of use for wireless telecommunication systems in order to ensure stable and reliable operation in conditions of dynamic changes in the environment and a high level of interference.The article compares the mathematical methods of optimization, namely the gradient method and Newton's method, proposes mathematical models and constructs algorithms that empirically prove the effectiveness of the application of the studied mathematical methods in the specified scientific area - for optimizing the parameters of ensembles of complex signals. Scientific works [1-6, 9, 12] present algorithms based on the gradient method and Newton's method, but they do not consider in detail the comparative analysis of the effectiveness of these methods for optimizing the parameters of ensembles of complex signals for implementation in various scientific and practical tasks. The effectiveness of the algorithms proposed in the article was confirmed experimentally, which made it possible to reduce the error and improve the characteristics of ensembles of complex signals.As a result of the experiments using the methods of gradient descent and Newton, a significant reduction of the error and an improvement of the stability of the signals were achieved. Newton's method reduced the error from 0.1 to 0.0027, justifying the high accuracy of setting the signal parameters. The gradient descent method provided a stable reduction of the gradient norm from 12.75 to less than 1.23, effectively reducing the interference level, i.e. increasing the interference immunity.
Hematobiochemical Changes, Immunological Response and Immune Gene Expression in Nile Tilapia (Oreochrom niloticus) Experimentally Infected with Shewanella putrefaciens
Authors: Philominal P. , Uma A. , Ahilan B. , Jayakumar N. 
Published: October 2024

Background: In this work, hematobiochemical changes, immunological responses, and histopathological changes in Nile tilapia (Oreochromis niloticus) experimentally infected with Shewanella putrefaciens were studied. Methods: O. niloticus was experimentally infected with S. putrefaciens (4SK/SRLFDA/19) at a concentration of 1.508×106CFU/ml per fish. Gross symptoms, namely hemorrhage on the body surface, skin discoloration, slow or nervous behavior, shallow necrotizing ulcers on the skin, fin erosions and abdominal distension were observed 5 to 6 days after infection. Fish were anesthetized and blood samples were collected at 0, 2, 4, 7, 10, 14, 20 and 27 days after the experimental infection to assess the hematobiochemical and immunological responses. For haematobiochemical responses, tests that included hemoglobin (Hb), leukocyte count (Lc), erythrocyte, hematocrite (Ht), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), cholesterol (CHO), glucose (GLU) and triglyceride were assessed. Result: Values of hematocrit, hemoglobin, albumin, globulin, erythrocyte, MCHC, cholesterol and triglyceride were significantly (p less than 0.05) decreased. Lc, MCV, MCH, and glucose values were significantly (p less than 0.05) increased. Respiratory burst activity (RBA) and serum total protein values were significantly (p less than 0.05) decreased. Relative expression of immune gene toll like receptor 4 (TLR4), stress genes heat shock proteins 70, 90 (HSP70, HSP90), oxidative stress gene glutathione S-transferases (GST) and inflammatory gene interleukin 6 (IL6) was significantly higher in experimentally infected fishes compared to control.
Dynamique d'occupation et d'utilisation des terres dans la Forêt Classée de Tiogo au Burkina Faso : caractérisation, moteurs et impacts sur la diversité et le stock de carbone ligneux
Authors: KONATE Ibrahim , ILBOUDO Daniel , DAYAMBA Sidzabda Djibril , TRAORÉ Salifou , SAWADOGO Louis , HIEN Mipro 
Published: October 2024

L’état de dégradation des forêts est une préoccupation mondiale particulièrement pour l’Afrique. De ce fait, plusieurs forêts classées sont de plus en plus menacées d’extinction dont les causes sont anthropiques et climatiques. L’étude a évalué la dynamique du couvert végétal et ses implications sur le stock de carbone aérien et la diversité ligneuse de la Forêt Classée de Tiogo au Burkina Faso. Une analyse d’images Landsat des années 1990, 1999, 2009 et 2019, et des données socioéconomiques et d’inventaire forestier ont été combinées dans différentes unités d’occupation des terres : savane arborée, savane arbustive, forêt galerie et cultures pluviales et territoires agroforestiers. Entre 1990 et 2019, 47 % de la superficie des savanes arborées a été perdue au profit des savanes arbustives et des cultures pluviales et territoires agroforestiers. Les feux de brousse, la coupe du bois et l’activité agricole constituent les principaux facteurs de dégradation. Les valeurs de la diversité ligneuse de la savane arborée (2,14 ± 0,31) et de la savane arbustive (1,92 ± 0,43) étaient plus élevées que celles des cultures pluviales et territoires agroforestiers (1,31 ± 0,62) et de la forêt galerie (0,63 ± 0,41). La forêt galerie avait le plus important potentiel de stock de carbone aérien (35,5 tC/ha), suivi de la savane arborée (7,1 tC/ha), puis de de la savane arbustive (2,5 tC/ha) et des cultures pluviales et territoires agroforestiers (1,7 tC/ha). Les changements d’unités d’occupation des terres dans la Forêt Classée de Tiogo ont induit entre 1990 et 2019, une réduction de 41 % du potentiel du stock de carbone aérien. Il en ressort le besoin de promouvoir des alternatives pour les moyens de subsistance et l’énergie pour les ménages, et le renforcement des initiatives de sensibilisation.
Diffusion properties of Gabonese tropical hardwoods and European softwoods measured with low-tech equipment and by an inverse method
Authors: ASSEKO ELLA Martian , BONTEMPS Arthur , GODI Gaël , MOUTOU-PITTI Rostand , GOLI Giacomo , IKOGOU Samuel , FOURNELY Eric , GRIL Joseph 
Published: October 2024

This paper presents an experimental approach to studies of the sorption and diffusion properties of wood. Five timber species - three African tropical hardwoods, Padauk, Okoume and Iroko, and two temperate softwoods, Silver fir and Douglas fir - were studied in adsorption mode. Specimens with 10- and 20-mm longitudinal (L) and transverse (RT) thickness were waterproofed on their sides to force diffusion in those directions. After kiln drying the specimens were hung with nylon wires under cover in a home-made box in which salt solutions provided constant relative humidity (RH), and conditioned at 43, 55, 75, 84 and 97% RH in successive steps. Temperature was maintained between 20 and 24°C. During the equilibration steps the samples were periodically weighed without altering the environmental conditions imposed, by hanging the nylon wire to a spring gauge through a small hole in the box cover. The sorption isotherm properties and diffusion parameters were obtained using an inverse method based on optimization of a 1D finite difference model. The parameters obtained show a decreasing correlation between diffusion coefficient and density, as observed by several authors in the literature. They also illustrate the impact of extractives on the sorption isotherm parameters. These results show that tropical species with high density or many extractives behave very differently to European softwoods, which impedes the application of Eurocode 5 equilibrium standards for these species.
PERAN EKSTRAKURIKULER PASKIBRA SMK GANESHA TAMA BOYOLALI DALAM PEMBENTUKAN GENERASI MUDA YANG TANGGUH DAN BERKARAKTER
Authors: Karsono Karsono , Noviansyah Wahyu 
Published: October 2024

<p><strong>A</strong><strong>b</strong><strong>strak</strong></p><p>Generasi muda merupakan tumpuan harapan bangsa. Masa depan bangsa bergantung pada generasi muda yang tangguh dan berkarakter. Di era globalisasi ini, generasi muda dihadapkan pada berbagai rintangan dan tantangan yang kompleks, seperti kemerosotan moral, maraknya narkoba, dan pengaruh budaya asing yang tidak sesuai dengan nilai-nilai Pancasila. Oleh karena itu, diperlukan upaya nyata untuk membentuk generasi muda yang tangguh dan berkarakter, salah satunya melalui kegiatan ekstrakurikuler. Salah satu kegiatan ekstrakurikuler yang memiliki potensi besar untuk membentuk generasi muda yang tangguh dan berkarakter adalah Paskibra (Pasukan Pengibar Bendera). Kegiatan ekstrakurikuler paskibra (Pasukan Pengibar Bendera) merupakan salah satu organisasi kesiswaan diluar pelajaran formal di SMK Ganesha Tama Boyolali yang merupakan wadah untuk membangun kedisiplinan, kemandirian, kepemimpinan, pembentukan sikap sebagai contoh generasi muda yang tangguh dan berkarakter. Penelitian ini bertujuan untuk menganalisis peran ekstrakurikuler Paskibra SMK Ganesha Tama Boyolali dalam pembentukan generasi muda yang tangguh dan berkarakter. Metode yang digunakan berupa deskriptif kualitatif dengan pendekatan studi kasus. Hasil penelitian menunjukkan bahwa ekstrakurikuler Paskibra terbukti efektif dalam menumbuhkan disiplin, keterampilan, karakter, moral, kepercayaan diri, rasa persahabatan, semangat persatuan, dan kekompakan pada diri para siswa. Keberhasilan Paskibra tidak lepas dari peran penting pembina dan kepala sekolah. Namun masih terdapat beberapa kendala yang perlu diatasi, seperti kurangnya minat siswa, fasilitas yang belum memadai, dan belum adanya kerjasama dengan orang tua. Saran yang diberikan adalah meningkatkan kualitas pelatihan, menyediakan fasilitas yang memadai, meningkatkan kerjasama dengan orang tua, melaksanakan kegiatan yang lebih variatif, dan mengembangkan jaringan dan kerjasama dengan instansi lain.</p><p> </p><p><strong>Kata Kunci:<em> Berkarakter, Ekstrakurikuler, Generasi Muda, Paskibra, Tangguh.</em></strong></p>
Data Quality in State Registry Reports of Medical Cannabis Patients in the United States
Authors: Boehnke Kevin F. , Sinclair Rachel , Gordon Felicia , Roehler Douglas R. , Smith Tristin , Hoots Brooke 
Published: October 2024

Objectives. To investigate characteristics of data reported in US medical cannabis registries across states. Methods. Data included 2021 medical cannabis registry reports from 34 states, Puerto Rico, and the District of Columbia (hereafter, states) with active medical cannabis programs. The data from the reports were manually coded into domains and subcategories, including information related to patients (e.g., number, demographics), authorizing clinicians, sales (e.g., content, revenue), license tracking, and health and safety outcomes. Results. Among 36 states, 97% reported total patient number and 75% reported number of authorizing clinicians. Least reported subcategories included patient race/ethnicity (8%), adverse events (11%), therapeutic benefits (6%), and product recalls (6%). States that recently legalized medical cannabis (2013–2018) reported a higher number of subcategories overall, with a median of 11 versus 8 for early adopting states (1996–2012). More medical-use states reported data on authorizing clinicians compared with nonmedical adult-use states but were otherwise similar. Conclusions. Medical cannabis state registries generally reported data on consumers, clinicians, and sales rather than health and safety outcomes. More comprehensive and uniform medical cannabis public health surveillance is needed. ( Am J Public Health. 2024;114(S8):S685–S693. https://doi.org/10.2105/AJPH.2024.307728 )
Association of Local Cannabis Policy and Retail Availability With Cannabis Use and Problematic Cannabis Use Among Adolescents in Northern California
Authors: Young-Wolff Kelly C. , Asera Alex , Padon Alisa A. , Slama Natalie E. , Alexeeff Stacey E. , Pacula Rosalie L. , Campbell Cynthia I. , Sterling Stacy A. , Satre Derek D. , Lu Yun , Dyer Wendy T. , Does Monique B. , Silver Lynn D. 
Published: October 2024

Objectives. To examine whether local cannabis policies and retail availability are associated with cannabis use and problematic cannabis use (PCU) among adolescents in Northern California. Methods. The sample comprised adolescents aged 13 to 17 years screened for past-year cannabis use during well-child visits in 2021. Exposures included local bans on cannabis storefront retailers, policy protectiveness, and retail proximity and density. Outcomes included self-reported past-year cannabis use and PCU diagnoses. Modified Poisson regression models adjusted for sociodemographics. Results. The sample (n = 103 134) was 51.1% male with a median age of 15 years (interquartile range [IQR] = 14–16 years); 5.5% self-reported cannabis use, and 0.3% had diagnosed PCU. Adolescents had a lower prevalence of cannabis use in jurisdictions that banned storefront retailers (adjusted prevalence rate [APR] = 0.857; 95% confidence interval [CI] = 0.814, 0.903 vs allowed), banned delivery (APR = 0.751; 95% CI = 0.710, 0.795 vs allowed), or had more policy protections (APR range = 0.705–0.800). Lower PCU prevalence was also found among those in jurisdictions that banned (vs allowed) storefront retailers (APR = 0.786; 95% CI = 0.629, 0.983) or delivery (APR = 0.783; 95% CI = 0.616, 0.996). Longer drive time and lower density of storefront retailers were associated with a lower cannabis use prevalence. Conclusions. More protective cannabis policies and less retail availability were associated with a lower prevalence of adolescent cannabis use and PCU. ( Am J Public Health. 2024;114(S8):S654–S663. https://doi.org/10.2105/AJPH.2024.307787 )
Corticosteroid Effects on Upper Esophageal Sphincter Function in Anterior Cervical Discectomy and Fusion
Authors: Lai Chih-Jun , Chen Jo-Yu , Jhuang Jing-Rong , Hsiao Ming-Yen , Wang Tyng-Guey , Yeh Yu-Chang , Lai Dar-Ming , Tsuang Fon-Yih 
Published: October 2024

Background:
The aim of our study was to explore the effect of local corticosteroids on dysphagia in patients undergoing anterior cervical discectomy and fusion (ACDF). To address a gap in the limited research on this topic, we utilized high-resolution impedance manometry (HRIM) and the Eating Assessment Tool-10 (EAT-10) questionnaire to assess the effects on key swallowing muscles, including the upper esophageal sphincter (UES).

Methods:
We randomly assigned patients undergoing ACDF to either the corticosteroid group or the saline solution group. Patients received 10 mg of local triamcinolone or saline solution prevertebrally at the cervical spine level before wound closure. Swallowing function preoperatively and at 1 month postoperatively were compared between the groups with use of HRIM parameters (e.g., UES relaxation, UES opening extent, intrabolus pressure, and pharyngeal contraction) and EAT-10 scores. Patients were also followed for postoperative complications and mortality within 12 months after surgery.

Results:
Thirty patients completed the study. The median age was 55 years in the corticosteroid group and 57 years in the saline group, and each group had 8 female patients. All participants were Taiwanese. We found no significant difference in median preoperative UES relaxation pressure between the corticosteroid and saline solution groups (33.8 and 31.3 mm Hg, respectively; p = 0.54). Postoperatively, the corticosteroid group had significantly lower median UES relaxation pressure than the saline solution group (24.5 versus 33.6 mm Hg; p = 0.01). Before and after surgery, all other HRIM parameters and EAT-10 scores were similar between the groups, with the corticosteroid group demonstrating median pre- and postoperative EAT-10 scores of 0 and 4, respectively, and the saline solution group demonstrating scores of 2 and 3, respectively. There were no adverse events.

Conclusions:
The findings suggest that local corticosteroids may reduce UES relaxation pressure at 1 month after ACDF, potentially enhancing UES opening. Further research is required to verify our findings.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Suitability assessment of planned landfill site selection using GIS and the Analytic Hierarchy Process (AHP) approach in Boditi city, southern Ethiopia
Authors: Balta Mathewos Muke , Gamo Kataro Galasso 
Published: October 2024

Abstract

Deciding the location of facility sites in an area with partial planning and a highly growing city is challenging for decision-making. It is even more difficult when assessing suitable site choice for solid waste. This study used geospatial data to assess suitable landfill site locations hoping to create a neat city using geospatial data for Boditi city, southern Ethiopia. Geographic information systems (GIS) and a multicriteria approach were used with other criteria to help select suitable locations. Biased comparisons and weighted scoring methods were used to evaluate the ten criteria used by the city to decide which site was suitable. The locations are sorted into four groups, stretching from highly suitable to unsuitable, using suitability mapping. Overall, of the 3,040 ha, 138.7 ha (4.56%) was considered highly suitable, while 2414 ha (79.41%) was considered moderately suitable for landfill sites. In addition, 476.21 ha (15.66%) was identified as less suitable, leaving the remaining 11.09 ha (0.37%) considered unsuitable. The study selected the best landfill site in terms of accessibility, topography, and compensation cost, in addition to ten criteria that will help minimize the risk of adverse impacts on life, land, water, and air environments associated with waste disposal.