bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Protective Mat Thickness on the Upper Limb Strike Force Simulation in Combat Sports and Self Defense
Authors: Beranek Vaclav , Stastny Petr , Bacik Bogdan , Bonkowski Tomasz , Novacek Vit 
Published: October 2024

The strike force in combat sports strongly depends on the protective material's mechanical properties and energy absorption capacity. Therefore, this study aimed to estimate the effect of the protective layer thickness and repeated loading on the net force in a falling weight impact test. A falling 8-kg weight dropped from 15 cm, 25 cm, and 50 cm was used to simulate impact peak forces in an upper limb strike. Transfer linear regression functions were identified for three layers of different thickness (1.8 cm, 3.6 cm, and 5.4 cm) between the measured force and undamped force that would be measured if no protective layer was used. A decrease in damping performance under repetitive loading was assessed for the same amount of energy (30 J) absorbed by the specimens. There were 36 specimens examined in 126 tests. When the measuring apparatus was covered with one, two or three layers of Trocellen foam, the undamped force was approximately 2.8, 6.1, and 11.1 times higher, respectively (p < 0.05, R2 ≥ 0.95), than the force measured in the kinetic design. This allows researchers to select the number of layers according to the individual needs in terms of safety and injury prevention. A single layer of Trocellen foam used in this study may be insufficient to ensure the safety of athletes in upper limb strike experiments due to possible compaction of the foam structure for deformations exceeding 80% compression and forces exceeding 5 kN, although no injury was previously observed.
KẾT QUẢ ĐIỀU TRỊ UNG THƯ VÒM HỌNG TÁI PHÁT DI CĂN BẰNG GEMCITABINE-CISPLATIN TẠI BỆNH VIỆN UNG BƯỚU NGHỆ AN
Authors: Nguyễn Thị Hiếu , Nguyễn Thị Thái Hòa , Nguyễn Thị Thái Hòa , Vũ Hồng Thăng 
Published: October 2024

Mục tiêu: Đánh giá kết quả điều trị bệnh nhân ung thư vòm mũi họng di căn bằng phác đồ Gemcitabine – Cisplatin tại Bệnh viện Ung bướu Nghệ An. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả trên 39 người bệnh ung thư vòm họng di căn, điều trị bước một phác đồ Gemcitabine - Cisplatin tại bệnh viện Ung bướu Nghệ An từ tháng 01/2019 đến tháng 04/2024. Kết quả: Vị trí di căn thường gặp là phổi (43,6%), tiếp theo là gan (38,5%); xương (33,3%). Tỉ lệ đáp ứng chung (ORR) là 71,7%. Trung vị thời gian sống thêm không tiến triển là 9,0 tháng. Các độc tính hay gặp là hạ bạch cầu 74,3%, thiếu máu 64%, buồn nôn 56,4%, nôn 43,6% trong đó phần lớn các độc tính gặp ở độ 1,2. Kết luận: Gemcitabine – Cisplatin cho thấy có hiệu quả và dung nạp được ở bệnh nhân ung thư vòm mũi họng di căn.
NGHIÊN CỨU TỔNG QUAN KẾT QUẢ LUYỆN GIỌNG ĐIỀU TRỊ LIỆT DÂY THANH MỘT BÊN
Authors: Triệu Thị Ngọc Anh , Nguyễn Quang Trung 
Published: October 2024

Mục tiêu: Mô tả kết quả luyện giọng điều trị liệt dây thanh một bên giai đoạn 2008-2023. Thiết kế nghiên cứu: Tổng quan luận điểm: Nghiên cứu tìm kiếm trên sở dữ liệu PubMed, Google scholar để xác định các bài báo liên quan đến kết quả luyện giọng điều trị liệt dây thanh một bên từ năm 2008 đến 2023. Kết quả: Tổng cộng 768 nghiên cứu đã được tìm kiếm. Sau cùng 12 nghiên cứu đáp ứng các tiêu chí được lựa chọn để báo cáo tổng quan. Trong đó có 1 nghiên cứu là thử nghiệm lâm sàng ngẫu nhiên có đối chứng, 3 nghiên cứu tiến cứu, 8 nghiên cứu hồi cứu mô tả từng ca bệnh với tổng số 828 bệnh nhân. Thang điểm đánh giá trong các nghiên cứu là qua công cụ do bệnh nhân tự điền như bảng chỉ số khuyết tật giọng nói Voice handicap index (VHI), đánh giá bằng phân tích chất thanh, nội soi thanh quản, thang đo GIRBAS, thời gian phát âm tối đa (MPT). Kết quả thang điểm VHI cho thấy tất cả các chỉ số liên quan đến thực thể, chức năng, cảm xúc đều được cải thiện rõ rệt với p <0,001. Phân tích chất thanh thấy các chỉ số Jitter, Shimmer, NHR đều cải thiện so với trước điều trị với p < 0,05. Nội soi thanh quản, sau luyện giọng thấy tỷ lệ đóng thanh môn hoàn toàn tăng đáng kể với p <0,001. Thời gian phát âm tối đa của bệnh nhân đều được cải thiện với p<0.05. Kết luận: Luyện giọng điều trị liệt dây thanh một bên là phương pháp điều trị hiệu quả, được đánh giá qua các thang điểm như phân tích chất thanh, VHI, nội soi thanh quản, thang đo GIRBAS, thời gian phát âm tối đa. Cho thấy các chỉ số liên quan đến chất lượng giọng nói đều cải thiện rõ ràng và đáng kể, tình trạng thanh môn đóng hoàn toàn sau điều trị, cải thiện tình trạng khó phát âm, cải thiện chất lượng cuộc sống của bệnh nhân.
Land cover succession for recently drained lakes in permafrost on the Yamal Peninsula, Western Siberia
Authors: von Baeckmann Clemens , Bartsch Annett , Bergstedt Helena , Efimova Aleksandra , Widhalm Barbara , Ehrich Dorothee , Kumpula Timo , Sokolov Alexander , Abdulmanova Svetlana 
Published: October 2024

Abstract. Drained lake basins (DLBs) are dominant features in lowland permafrost landscapes of the Arctic. Here, we present a novel approach describing and quantifying the succession progression of recently drained basins using a land cover unit retrieval scheme developed specifically for the Arctic tundra biome. The complementarity between land cover units and Normalized Difference Vegetation Index (NDVI) analyses is shown. Land cover units were linked to DLB ages (years passed since a drainage event occurred). The data were divided into bioclimate subzones, and the land cover units were grouped according to their characteristics, first related to vegetation and second to wetness gradients (dry, moist and wet). Regression analyses of NDVI values and fraction of each land cover unit group provided the justification for the utility of the units in our research. The regression results showed the highest correlation with NDVI values for the wetness group “Moist” and the vegetation group “Shrub Tundra” (R2=0.458 and R2=0.444). There was no correlation (R2=0.066) between NDVI and the fraction of the “Wet” group. The inconsistency in the association between those variables underlines the need to complement NDVI analyses with a scheme representing wetness, such as the use of land cover units to describe changes in wetland areas. Finally, our results showed different trajectories in the succession of land cover units in recently drained lake basins with respect to different bioclimate subzones. Remaining water in the basin after a lake drainage event was highest for the most southern subzone (median 6.28 %). The open water fraction dropped below 1 % for all subzones after 5 to 10 years since drainage. The results of this study contribute to an improved understanding of DLB land cover change in permafrost environments and to a better knowledge base of these unique and critically important landforms.
The Sixth Amendment Right to Fair Sentencing: An Analysis of Acquitted, Dismissed, and Uncharged Conduct Under the Federal Sentencing Guidelines
Authors: Scapicchio Daniel 
Published: October 2024

This Note examines three scenarios in which the relevant conduct provision of the Federal Sentencing Guidelines implicates the Sixth Amendment right to a jury trial. The U.S. Sentencing Commission recently proposed an amendment to the Federal Sentencing Guidelines, which would forbid judges from considering so-called "acquitted conduct" at sentencing. The current interpretation of the relevant conduct provision allows a sentencing judge to consider a criminal defendant's conduct, regardless of whether the defendant was found guilty of that conduct at trial. Relying on acquitted conduct, a judge may decide that a defendant who was found guilty of one charge and acquitted of another must serve a sentence as if they had been convicted of both. While the acquitted conduct amendment would address the most glaring Sixth Amendment issue presented by the relevant conduct provision, this note argues that there are at least two other sentencing practices that present the same problem. First, when a charge against a defendant gets dismissed, the judge may still consider the conduct underlying that charge at sentencing (dismissed conduct). Second, a sentencing judge may consider a defendant's conduct even if the defendant was never formally charged for an offense relating to that conduct (uncharged conduct). Because the sentencing judge reviews relevant conduct under a preponderance of the evidence standard, as opposed to the stricter, beyond a reasonable doubt standard that a jury would be held to, the relevant conduct provision presents major Sixth Amendment issues which warrant further consideration. If the Sentencing Commission does away with acquitted conduct sentencing, this Note argues that dismissed and uncharged conduct should follow.
GAMBARAN PENGETAHUAN TENTANG MODIFIKASI GAYA HIDUP TERHADAP PENCEGAHAN STROKE BERULANG DI RSUP H. ADAM MALIK MEDAN TAHUN 2023
Authors: Jagentar P. Pane  , Agustaria Ginting  , Geba Kresensia Anne Getrini 
Published: October 2024

Pendahuluan. Stroke merupakan salah satu penyakit serebrovaskular yang terjadi karena adanya penyumbatan atau pecahnya pembuluh darah pada otak. Pengetahuan mengenai penyakit stroke sangat rendah, pemahaman dan kesadaran untuk faktor resiko timbulnya stroke, kurang pengetahuan mengenai gejala-gejala stroke, kurang optimalnya pelayanan untuk pasien stroke dan kurangnya ketaatan terhadap terapi untuk pencegahan stroke berulang adalah masalah yang muncul di Indonesia. Empat hal ini berkontribusi dalam meningkatnya kejadian stroke baru, makin tingginya angka kematian karna stroke, dan semakin tinggi kejadian stroke berulang.
Tujuan. penelitian ini bertujuan untuk mengetahui pengetahuan pasien stroke tentang modifikasi gaya hidup terhadap pencegahan stroke berulang
Metode. Penelitian ini bersifat deskriptif dengan metode cross sectional menggunakan kuesioner dengan jumlah sampel 39 orang
Hasil. didapatkan hasil bahwa dari 39 responden pengetahuan kurang sebanyak 26 orang (66,7%), pengetahuan cukup sebanyak 7 orang (17,9%) dan baik sebanyak 6 orang (15,4%).
Kesimpulan. Hasil penelitian ini menunjukan bahwa pengetahuan pasien tentang modifikasi gaya hidup terhadap pencegahan stroke berulang masih kurang.
HUBUNGAN DUKUNGAN KELUARGA DENGAN KEPATUHAN DIET LANSIA PADA PENDERITA HIPERTENSI DI PUSKESMAS PAJANG SURAKARTA
Authors: Fadira Nindya Akhirana  , Marni  , Marsudarinah  
Published: October 2024

Pendahuluan : Hipertensi merupakan masalah kesehatan di seluruh dunia, termasuk di Indonesia. Keluarga menjadi support system dalam kehidupan sehari-hari pasien hipertensi. Dukungan keluarga sangat penting dalam meningkatkan kepatuhan diet lansia pada penderita hipertensi.
Tujuan : Penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga dengan kepatuahan diet lansia pada penderita hipertensi di Puskesmas Pajang Surakarta.
Metode Penelitian : Jenis penelitian ini adalah kuantitatif dengan desain deskriftif corellational dan pendekatan cross sectional, penelitian ini dilaksanakan pada tanggal 8 â€“ 22 Maret 2024. Pengumpulan data menggunakan kuesioner, dengan jumlah responden 60 orang, menggunakan teknik random sampling, data yang di peroleh di olah menggunakan uji statistik rank spearman.
Hasil : Berdasarkan hasil analisis di peroleh data dari 60 lansia yang memiliki dukungan keluarga baik dengan kepatuhan dalam kategori patuh sebanyak 53 responden (88,3%), dukungan keluarga baik dengan kepatuhan dalam kategori tidak patuh sebanyak 7 responden (11,7%). Hasil uji rank spearman di dapatkan p-value = 0,000 (< 0,05).
Kesimpulan : Ada hubungan dukungan keluarga dengan kepatuhan diet lansia pada penderita hipertensi di Puskesmas Pajang Surakarta
MHD Al2O3/Cu-water Casson hybrid nanofluid flow across a porous exponentially stretching sheet
Authors: Paul Ashish , Sarma Neelav , Patgiri Bhagyashri 
Published: October 2024

This study examines the heat and mass transmission of MHD Al2O3-Cu / H2O Casson hybrid- across an exponentially stretching porous sheet under the effect of non-uniform heat source/sink and chemical reaction. The nonlinear coupled ODEs are solved using the 3-stage Lobatto IIIa formula and the built-in MATLAB scheme Bvp4c after being converted from the governing nonlinear PDEs by appropriate similarity transformations. The numerical findings are compared with previously available works of literature in order to validate our investigations, and it transpires that there is a good agreement. Graphs are used to illustrate how dimensionless parameters such as the Casson parameter, magnetic parameter, radiation parameter, porosity parameter, Lewis number, the non-uniform heat source/sink parameter, and chemical parameter may affect a system. The impact of the Casson parameter on skin friction coefficient, Nusselt number, and Sherwood number are depicted in the table. The Casson hybrid nanofluid has been found out to have a greater thermal conductivity than the comparable Casson nanofluid. It was also found that the absolute value of the coefficient of skin friction & Nusselt number for Casson hybrid-nanofluid is increased by about 28% and 15% respectively when compared with Casson nanofluid.
Combined fluid and ferrofluid buoyancy force, heat absorption and non linear ferro-viscosity effects on ferro- hydrodynamics fluid flow in orthogonal porous surface
Authors: Maleque Kh. Abdul 
Published: October 2024

Mixed convection incompressible ferro-hydrodynamic (FHD) boundary layer fluid flow on vertical porous curvilinear orthogonal surfaces is examined in our present study in presence of combined fluid and ferro-fluid buoyancy force, nonlinear ferro-viscosity parameter, and heat absorption/generation effects.
Design/Methodology/Approach: Types of Prandtl momentum and thermal boundary layer partial differential equations in a curvilinear system are converted into non-dimensional ordinary nonlinear differential equations (ODE) by introducing dimensionless velocities, temperature functions and similarity variable. Missing initial conditions are found by shooting method and solving the system of nonlinear ODEs by Runge-Kutta integration scheme of order six. With the help of MATLAB, the numerical solutions are graphically displayed in the forms of primary velocity profile, secondary velocity profile, and temperature profile. Three types of magnetic nano-ferrofluid are considered such as water-based ferrofluid (Taiho W-40), Hydrocarbon based ferrofluid (EMG-901) and kerosene-based ferrofluid (C1-20B) whose Prandtl numbers are 44.3, 79.3 and 128 respectively shown in Table 1. For kerosene based ferro-fluid, Table 3 presents the coefficient of skin friction and heat flux.
Finding: The effects of combined fluid and ferrofluid buoyancy forces, nonlinear ferro-viscosity parameter, suction/injection, and heat absorption/generation parameters on the velocity and temperature profiles are investigated. Our physical interest is to calculate the local shearing stresses and the local heat flux at the surface. Finally, we have made comparisons of the results which are highlighted the validity of our numerical calculations adopted for the presence study.
Control of shock-induced separation using air-jet vortex generators
Authors: Schreyer Anne-Marie 
Published: October 2024

Shock-induced separation leads to highly unsteady flow fields and has strong detrimental effects on the aerodynamic behavior and performance of numerous aerospace-engineering applications. To reduce these effects, separation control is required. A very promising approach is the use of rows of air-jet vortex generators (AJVGs), where small spanwise-inclined jets of air injected into the flow increase the momentum transfer within the boundary layer and thus make it less prone to separation. A large number of parameters influence the control effectiveness of AJVGs, amongst them geometrical parameters, such as the orifice shape, orifice size, and injection-pipe length; flow parameters, including the (steady or forced) injection pressure; and the array arrangement. The talk will provide an overview on the relevant control parameters and their respective influences, also comparing AJVGs with classical mechanical vortex generators. Recent experimental and numerical studies at RWTH Aachen University provide a rich experimental-numerical data set, which we have jointly analyzed and interpreted using statistical methods and modal analysis with dynamic-mode decomposition, amongst other techniques. On the basis of these results, the physical mechanisms and underlying flow dynamics governing the control effect of AJVGs, as well as the observed flow phenomena and control effects, will be presented and discussed.
Keep the physics in the model if you can: Data assimilation in Fluid Mechanics
Authors: Juniper Matthew 
Published: October 2024

"This talk will show one way to combine physics-based modelling with data-driven machine learning. The method assimilates data into physics-based models using Bayesian inference accelerated with adjoint methods. It quantifies the uncertainties in the model parameters and the uncertainties in the model predictions. If the physics of the problem is known, this method is usually better than assimilating data into a Neural Network. This is because the physics-based model requires less training data, is interpretable, and extrapolates to situations that share the same physics. This framework also rigorously compares candidate physics-based models against each other, allowing the best model to be selected. This work is inspired by David MacKay's book on information theory, inference, and learning algorithms (https://www.inference.org.uk/itprnn/book.pdf). I will present applications in Magnetic Resonance Imaging of flows (flow-MRI) and thermoacoustic oscillations in rockets and aicraft engines. An overview of the talk can be found at https://mpj1001.user.srcf.net/MJ_inference.html."
Integrating psychological interventions into holistic management of chronic respiratory diseases
Authors: Sundar Devi 
Published: October 2024

Chronic Respiratory Diseases (CRD), such as asthma, interstitial lung disease, and chronic obstructive pulmonary disease (COPD), have a significant negative influence on a patient's physical and mental health. Stress, anxiety, and depression are common psychological injuries that worsen lung function, and increase mortality, exacerbations, and healthcare utilization in patients with chronic respiratory disease (CRD). Pulmonary rehabilitation is a gold standard non-pharmacological management for CRD—where care delivery strategies are based on a bio-psycho-social model of integrated therapies. However, there are still issues since there are global differences in the way programs are designed and implemented, and there are no standardized psychological assessments or therapies available for patients with CRD. This review critically examines the challenges in standardizing pulmonary rehabilitation programs and the lack of health psychological assessment or interventions for patients with CRD. Additionally, it suggests necessary updates to respiratory physiotherapy curricula with the neuroscience of breathing in clarifying the relationship between psychological factors and inflammation in CRD. The review calls for an urgent need for increased global research funding to enhance psychological therapies as integrated respiratory care management and improve outcomes for patients with CRD.
Formação humana integral no contexto da EJA/EPT: reflexões a partir da perspectiva freiriana
Authors: Lima Antônio Carlos Santos de , Silva Ana Quitéria Menezes de Oliveira , Correia Aurineide Profírio Barros , Correia Alexandre Henrique Barros , Santos José Antônio de Oliveira dos , Beirouti Mayara Romeiro Lins , Silva Renata Alves da , Barbosa Tiago Jorge de Araújo 
Published: October 2024

Este artigo tem como objetivo refletir sobre a formação humana integral no contexto da Educação de Jovens e Adultos (EJA) integrada à Educação Profissional e Tecnológica (EPT), a partir de uma perspectiva freiriana. Com base em uma pesquisa de natureza qualitativa do tipo bibliográfica buscamos refletir como o ideal de educação freiriano relaciona-se com a natureza da EPT no contexto da EJA. Ancorado nos estudos de Paulo Freire, que defende uma educação dialógica e emancipatória, e em estudos de autores que discutem a EPT, que enfatizam a necessidade de a formação superar a abordagem tecnicista da educação, promovendo a construção de sujeitos críticos e autônomos, conclui-se que a formação humana integral, compreendida como um processo que abrange as dimensões cognitivas, éticas e sociais dos educandos, é apresentada como essencial para garantir que a EJA/EPT vá além da formação técnica, proporcionando uma educação que possibilite uma participação ativa e consciente na transformação social.
Prospecção de actinobactérias oriundas da areia de praia em São Luís – MA
Authors: Araújo Emanuelle Ketthlen Nunes , Ribeiro Elian Chaves , Jesus Ronald da Silva de , Silva Verônica Duarte da , Teixeira Raul da Cruz , Pinheiro Rosa Amélia Mendonça Sátiro , Pereira João Guilherme Santos , Miranda Rita de Cássia Mendonça de 
Published: October 2024

As Actinobactérias produzem metabólitos secundários com diversas bioatividades, como a antimicrobiana, que podem ser úteis contra cepas bacterianas resistentes. Visando a busca por compostos bioativos com propriedades de ação antibacteriana, objetiva-se com este estudo isolar e identificar micromorfológicamente actinobactérias presentes no sedimento de praia, com o intuito de avaliar atividade antagônica capaz de inibir o crescimento de patógenos multirresistentes. Para isso, duas cepas de actinobactérias (Streptomyces spp., e Streptosporagium spp.) denominadas PC2 e PC3, foram isoladas através da técnica de diluições seriadas e identificadas a nível de gênero pela técnica de microcultivo. Induziu-se atividade antagônica por meio do ensaio em meio sólido com intuito de produzir metabólitos secundários na tentativa de inibir e formar halos testando-se atividade antimicrobiana contra Candida albicans ATCC 14033, Klebsiella pneumoneae, Pseudomonas aeruginosa ATCC 7853 e Staphylococcus aureus ATCC 25923. Observou-se atividade antimicrobiana da cepa PC2 contra Klebsiella pneumoneae com formação de halo e inibição de 30 mm, e PC3 contra Pseudomonas aeruginosa ATCC 7853 com formação de halo e inibição de 15mm. Para as cepas Candida albicans e Staphylococcus aureus não apresentaram atividade antimicrobiana. A atividade antagônica dos respectivos isolados apresentou atividade antimicrobiana contra Klebisiella pneumoneae e Pseudomonas aeruginosa ATCC 7853; possibilitando mais estudos para ampliar seu espectro de ação e para formular antimicrobianos contra essas espécies.
Pharmacophore-based SAR Analysis and Synthetic Route Review of Imidazole Core Analogues
Authors: Priya Ravisekhar Mohana , Zaidh Salem Mohammed , Navabshan Irfan , Venkataraman Sowmiyalakshmi , Ahmed Haja Nazeer , Ismail Yousuf 
Published: October 2024

The five-membered nitrogen-containing heterocyclic moiety imidazole forms part of molecules that have been used to treat various diseases including life-threatening cancer. Moreover, the imidazole moiety is naturally present in various plants, marine, and microorganism-based metabolites and possesses various medicinal benefits. In this review, the pharmacophore-based substitution effect on the imidazole skeleton is primely compiled. A plethora of synthetic approaches have been adopted to develop imidazole hybrids, a number of which have been used as a basic skeleton for synthesizing other fused hybrids. Second, various recent synthetic methods, both in vitro and in vivo activities, are reviewed. Pharmacophoric examination showed that imidazole acts as a ring aromatic, or hydrophobic center depending on the type of substitution. While substitution with benzene ring, it acts only as a hydrogen bond donor and substitution with a hydrophobic ring and an aliphatic long chain on the imidazole ring leads to anticonvulsant and anti-inflammatory activity. The substitution of various electron-sharing features increases the antiulcerogenic property as well as anticancer activity. The results of this review work suggest that fabrication with specific pharmacophoric features aids in the synthesis of selective antagonist for various diseases.