bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterizing the role of unpredictability within different dimensions of early life adversity
Authors: Farkas Bence Csaba , Jacquet Pierre Olivier 
Published: October 2024

Abstract
Dimensional models of early life adversity highlight the distinct roles of deprivation and threat in shaping neurocognitive development and mental health. However, relatively little is known about the role of unpredictability within each dimension. We estimated both the average levels of, and the temporal unpredictability of deprivation and threat exposure during adolescence in a high-risk, longitudinal sample of 1354 youth (Pathways to Desistance study). We then related these estimates to later life psychological distress, and Antisocial and Borderline personality traits, and tested whether any effects are mediated by future orientation. High average levels of both deprivation and threat exposure were found to be associated with worse mental health on all three outcomes, but only the effects on Antisocial and Borderline personality traits were mediated by decreased future orientation, a pattern consistent with evolutionary models of psychopathology. Unpredictability in deprivation exposure proved to be associated with increased psychological distress and a higher number of Borderline traits, but with increased future orientation. There was some evidence of unpredictability in threat exposure buffering against the detrimental developmental effects of average threat levels. Our results suggest that the effects of unpredictability are distinct within different dimensions of early life adversity.
Nutritional and Culinary Habits to Empower Families (n-CHEF): a feasibility study to increase consumption and home cooking of plant-based foods
Authors: Goni Leticia , Simonin Luca , Rovayo Anacristina , Kury-Guzman Isabella , Martín-Calvo Nerea , Ruiz-Canela Miguel 
Published: October 2024

Abstract

Objective:
To analyse the feasibility and acceptability of a culinary nutritional intervention aimed at increasing plant-based foods consumption in the context of the Mediterranean diet in parent–child dyads.

Design:
The Nutritional and Culinary Habits to Empower Families (n-CHEF) is a 9-month feasibility study that included four culinary nutritional workshops (two face to face, two online) led by a chef and a dietitian-nutritionist. These workshops combined cooking with plant-based foods, with nutritional advice and experimental activities. The main outcomes were retention, quality of the intervention (monitoring workshops, acceptability and perceived impact) and changes in dietary and cooking habits.

Setting:
Parent–child dyads, Spain.

Participants:
Parent–child (aged 10–14 years) dyads.

Results:
Fifteen parent–child dyads were recruited, of which thirteen were retained during the 6-month follow-up. All but one parent–child dyads attended the four workshops. The overall assessment of the workshops was positive, although the online workshops were rated lower than the face to face. In general, parent–child dyads reported benefits in terms of nutrition and cooking aspects. Parents significantly increased their adherence to the Mediterranean diet, but non-significant changes were observed in children. However, children increased their consumption of vegetables and legumes and reduced snacks and ready meals. Parents also changed some of their culinary habits and increased their confidence in cooking at home.

Conclusions:
The n-CHEF showed that the culinary nutritional intervention had good levels of recruitment, retention and acceptability among parent–child dyads. In addition, dietary and culinary knowledge and habits can be improved, although further studies are needed to know the long-term effects in larger populations.
Effect of planting pattern and herbicide programs on sicklepod (Senna obtusifolia L.) control in peanut
Authors: Daramola Olumide S. , MacDonald Gregory E. , Kanissery Ramdas G. , Tillman Barry L. , Singh Hardeep , Ajani Oluseyi Ayodeji , Devkota Pratap 
Published: October 2024

Abstract
Sicklepod is one of the most difficult to control weeds in peanut production in the southeastern United States due to its extended emergence pattern and limited effective herbicides for control. Growers rely on preemergence herbicides as the foundation of their weed control programs; however, postemergence herbicides are often needed for season-long weed control. The objectives of this study were to evaluate the effect of planting pattern and herbicide combinations for sicklepod control in peanut crops. Due to rapid canopy closure, twin-row planting improved late-season sicklepod control by 13% and peanut yield by 5% compared with a single-row pattern. A preemergence application of fluridone, flumioxazin, or fluridone + flumioxazin provided 76% to 89% control of sicklepod 28 d after preemergence. Regardless of the herbicide applied preemergence, paraquat + bentazon + S-metolachlor applied early postemergence was required to achieve ≥90% sicklepod control 28 d after early postemergence. All preemergence herbicide treatments followed by (fb) S-metolachlor or diclosulam + S-metolachlor applied early postemergence provided <90% control 28 d after early postemergence. A mid-postemergence application of imazapic + dimethenamid-P + 2,4-DB controlled sicklepod by 67% to 79% prior to peanut harvest, and biomass reduction was unacceptable (<80%), resulting in difficulty in peanut digging. The highest peanut yield was observed when paraquat + bentazon + S-metolachlor was applied early postemergence fb imazapic + dimethenamid-P + 2,4-DB applied mid-postemergence. Based on the results of this study, a herbicide combination of paraquat + bentazon + S-metolachlor is an important early-season tool for controlling sicklepod in peanut crops. The results also showed that a twin-row planting pattern improved late-season sicklepod control but did not reduce herbicide input to protect peanut yield.
Negative Surface Chlorophyll Concentration Anomalies in the Southeast Arabian Sea During Summer in 2015 and 2019
Authors: Huang Huaming , Huang Ke , Yang Lei , Liang Zhanlin , Song Wei , Wang Dongxiao 
Published: October 2024

AbstractSatellite observations revealed two extremely low surface chlorophyll concentration (SCC) events with a warm sea surface temperature anomaly in the southeastern Arabian Sea (SEAS, 6°–15°N, 72°–77°E) during the summer (July–August–September) in 2015 and 2019. We find that the physical processes leading to these two similar low SCC events are remarkably different. The low SCC in the SEAS during summer 2019 is mainly related to the weakened upwelling and deepening of the thermocline depth due to the combined effects of the local wind anomalies and the arrival of westward‐propagating downwelling coastal Kelvin wave driven by easterly anomalies near the eastern Sri Lanka during an extreme positive Indian Ocean Dipole (IOD) event. In summer 2015, a weaker positive IOD‐induced easterly anomalies in the southern Bay of Bengal also drives downwelling coastal Kelvin waves westward, deepening the thermocline in the SEAS. But unlike that in summer 2019, the local wind stress curl anomalies in the SEAS during summer 2015 favors upwelling, which counteracts the downward motion of the coastal Kelvin waves, leading to weaker downward transport (one‐third of that in 2019). Meanwhile, the upper ocean layer in the SEAS experiences extreme warming during summer owing to the development of 2015/2016 super El Niño. This substantial warming enhances upper oceanic stratification, which results in weaker vertical mixing and reduces the SCC to an extremely low level despite the much weaker IOD strength in 2015.
Kilometer‐Scale Assessment of the Adriatic Dense Water Multi‐Decadal Dynamics
Authors: Pranić Petra , Denamiel Cléa , Vilibić Ivica 
Published: October 2024

AbstractThe North Adriatic Dense Water (NAddW)—the densest Mediterranean water generated by extreme cooling during wintertime hurricane‐strength winds—drives the thermohaline circulation, ventilates the deep layers, and changes the biogeochemical properties of the Adriatic Sea. However, modeling the dynamical properties of such dense water at the climate scale has been a challenge for decades due to the complex coastal geomorphology of the Adriatic basin not properly reproduced by existing climate models. To overcome these deficiencies, a 31‐year‐long simulation (1987–2017) of the Adriatic Sea and Coast (AdriSC) kilometer‐scale atmosphere‐ocean model is used to analyze the main NAddW dynamical phases (i.e., generation, spreading and accumulation). The study highlights four key results. First, during winter, the NAddW densities are higher in the shallow northern Adriatic shelf than in the deeper Kvarner Bay—where 25%–35% of the overall NAddW are found to be generated—due to a median bottom temperature difference of 2°C between the two generation sites. Second, the NAddW mass transported across most of the Adriatic peaks between February and May, except along the western side of the Otranto Strait. Third, for the accumulation sites, the bottom layer of the Kvarner Bay is found to be renewed annually while the renewal occurs every 1–3 years in the Jabuka Pit and every 5–10 years in the deep Southern Adriatic Pit. Fourth, the NAddW cascading and accumulation is more pronounced during basin‐wide high‐salinity conditions driven by circulation changes in the northern Ionian Sea.
TMCO1 is upregulated in breast cancer and regulates the response to pro-apoptotic agents in breast cancer cells
Authors: Bong Alice H. L. , Robitaille Mélanie , Lin Sichun , McCart-Reed Amy , Milevskiy Michael , Angers Stéphane , Roberts-Thomson Sarah J. , Monteith Gregory R. 
Published: October 2024

AbstractThe release of Ca2+ ions from endoplasmic reticulum calcium stores is a key event in a variety of cellular processes, including gene transcription, migration and proliferation. This release of Ca2+ often occurs through inositol 1,4,5-triphosphate receptors and the activity of these channels and the levels of stored Ca2+ in the endoplasmic reticulum are important regulators of cell death in cancer cells. A recently identified Ca2+ channel of the endoplasmic reticulum is transmembrane and coiled-coil domains 1 (TMCO1). In this study, we link the overexpression of TMCO1 with prognosis in node-positive basal breast cancer patients. We also identify interacting proteins of TMCO1, which include endoplasmic reticulum-resident proteins involved in Ca2+ regulation and proteins directly involved in nucleocytoplasmic transport. Interacting proteins included nuclear transport proteins and TMCO1 was shown to have both nuclear and endoplasmic reticulum localisation in MDA-MB-231 basal breast cancer cells. These studies also define a role for TMCO1 in the regulation of breast cancer cells in their sensitivity to BCL-2/MCL-1 inhibitors, analogous to the role of inositol 1,4,5-triphosphate receptors in the regulation of cell death pathways activated by these agents.
An architectural role of specific RNA–RNA interactions in oskar granules
Authors: Bose Mainak , Rankovic Branislava , Mahamid Julia , Ephrussi Anne 
Published: October 2024

AbstractRibonucleoprotein (RNP) granules are membraneless condensates that organize the intracellular space by compartmentalization of specific RNAs and proteins. Studies have shown that RNA tunes the phase behaviour of RNA-binding proteins, but the role of intermolecular RNA–RNA interactions in RNP granules in vivo remains less explored. Here we determine the role of a sequence-specific RNA–RNA kissing-loop interaction in assembly of mesoscale oskar RNP granules in the female Drosophila germline. We show that a two-nucleotide mutation that disrupts kissing-loop-mediated oskar messenger RNA dimerization impairs condensate formation in vitro and oskar granule assembly in the developing oocyte, leading to defective posterior localization of the RNA and abrogation of oskar-associated processing bodies upon nutritional stress. This specific trans RNA–RNA interaction acts synergistically with the scaffold RNA-binding protein, Bruno, in driving condensate assembly. Our study highlights the architectural contribution of an mRNA and its specific secondary structure and tertiary interactions to the formation of an RNP granule that is essential for embryonic development.
Electronic structure, global reactivity descriptors and nonlinear optical properties of glycine interacted with ZnO, MgO and CaO for bacterial detection
Authors: Sabry Noha M. , Badry Rania , Abdel-Gawad Fagr Kh. , Elhaes Hanan , Ibrahim Medhat A. 
Published: October 2024

AbstractModern laboratory medicine relies on analytical instruments for bacterial detection, focusing on biosensors and optical sensors for early disease diagnosis and treatment. Thus, Density Functional Theory (DFT) was utilized to study the reactivity of glycine interacted with metal oxides (ZnO, MgO, and CaO) for bacterial detection. Total dipole moment (TDM), frontier molecular orbitals (FMOs), FTIR spectroscopic data, electronic transition states, chemical reactivity descriptors, nonlinear optical (NLO) characteristics, and molecular electrostatic potential (MESP) were all investigated at the B3LYP/6–31G(d, p) level using DFT and Time-Dependent DFT (TD-DFT). The Coulomb-attenuating approach (CAM-B3LYP) was utilized to obtain theoretical electronic absorption spectra with the 6-31G(d, p) basis set to be more accurate than alternative quantum chemical calculation approaches, showing good agreement with the experimental data. The TDM and FMO investigation showed that glycine/CaO model has the highest TDM (10.129Debye) and lowest band gap (1.643 eV). The DFT computed IR and the experimental FTIR are consistent. The calculated UV-vis spectra showed a red shift with an increase in polarity following an increase in the absorption wavelength due to the interaction with ZnO, MgO, and CaO. Among the five solvents of water, methanol, ethanol, DMSO and acetone, the water and DMSO enhances the UV-Vis absorption. Glycine/CaO model showed high linear polarizability (14.629 × 10−24esu) and first hyperpolarizability (23.117 × 10−30esu), indicating its potential for nonlinear optical applications. The results showed that all model molecules, particularly glycine/CaO, contribute significantly to the development of materials with potential NLO features for sensor and optoelectronic applications. Additionally, MESP confirmed the increased electronegativity of the studied structures. Additionally, glycine/ZnO nanocomposite was synthesized and characterized using IR and UV-visible spectroscopy to determine their structural and spectroscopic features. It was discovered that there was good agreement between the DFT computed findings and the related experimental data. The antibacterial activity of glycine/ZnO nanocomposites against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa were studied in terms of concentration and time. The results showed that increasing the concentration of glycine/ZnO nanocomposite significantly enhanced its antibacterial efficacy by lowering optical density. Notably, Pseudomonas aeruginosa exhibited lower susceptibility to the nanocomposite compared to S. aureus, requiring higher concentrations for effective bactericidal action. In summary, this study contributes novel insights into the dual functionality of glycine-metal oxide complexes, with significant implications as optical biosensor for microbial detection.
Progression of disease within 24 months (POD24) in multiple myeloma implicates poor prognosis and limitations of current prediction models for POD24
Authors: Cao Yongqin , Gong Yingying , Wang Qingqing , Xia Jun , Zhou Xin , Sun Chao 
Published: October 2024

AbstractMultiple myeloma (MM) is a common hematological malignancy, and its prognostic factors have been extensively studied. Progression of disease within 24 months (POD24) suggests a poor prognosis in many malignancies, but is rarely mentioned in MM. This study aimed to investigate the prognostic value of POD24 in MM and risk factors of POD24, and to evaluate the predictive value of existing MM prognostic models for POD24. The research retrospectively analyzed the clinical data of MM patients and found that the occurrence of POD24 is an independent prognostic factor affecting overall survival in MM, while non-transplantion and genetic abnormality are independent risk factors for the occurrence of POD24. The existing prognostic models are not effective in predicting POD24. Therefore, it’s still necessary to explore a prognostic model that can predict POD24 more accurately.
Stochastic hexagonal injectors in artificial spin ice
Authors: Puttock Robert , Fondet Anaïs , Andersen Ingrid M. , Rosamond Mark C. , Fernández Scarioni Alexander , Schumacher Hans W. , Snoeck Etienne , Gatel Christophe , Kazakova Olga 
Published: October 2024

AbstractArtificial spin ice (ASI) systems have emerged as powerful platforms for exploring the fundamental aspects of magnetic frustration and topological phenomena in condensed matter physics. In this study, we investigate the bountiful effects that result from introducing hexagonal magnetic defects into an ASI lattice. The stochastic stabilisation of a plethora of metastable states in the hexagonal defects are explored, as well as harnessing the defect magnetisation state for the selective injection of emergent monopoles of different polarities and proximities within the lattice. We demonstrate a mechanism for tailoring the ASI behaviour using the magnetic state of the defect, which is of interest to applications including magnetic memory devices and spin-based logic.
KMnO4/Pb staining allows uranium free imaging of tissue architectures in low vacuum scanning electron microscopy
Authors: Sawaguchi Akira , Kamimura Takeshi , Kitagawa Kyoko , Nagashima Yoko , Takahashi Nobuyasu 
Published: October 2024

AbstractScanning electron microscopy under low-vacuum conditions allows high-resolution imaging of complex cell/tissue architectures in nonconductive specimens. However, the conventional methods for metal staining of biological specimens require harmful uranium compounds, which hampers the applications of electron microscopy. Here, we introduce a uranium-free KMnO4/Pb metal staining protocol that allows multiscale imaging of extensive cell/tissue architectures to intensive subcellular ultrastructures. The obtained image contrast was equivalent to that of Ur/Pb staining and sufficient for ultrastructural observation, showing the fine processes of podocytes in the glomerulus, which were invisible by light microscopy. The stainability in the elastic tissue indicated that the distinct histochemical properties of KMnO4 oxidation led to Pb deposition and BSE signal enhancement superior to Ur staining. Elemental analysis clarified that the determinant of the backscattered electron signal intensity was the amount of Pb deposition enhanced by KMnO4 oxidation. This user-friendly method is anticipated to create a new approach for biomedical electron microscopy.
Recent progress in spin-orbit torque magnetic random-access memory
Authors: Nguyen V. D. , Rao S. , Wostyn K. , Couet S. 
Published: October 2024

AbstractSpin-orbit torque magnetic random-access memory (SOT-MRAM) offers promise for fast operation and high endurance but faces challenges such as low switching current, reliable field free switching, and back-end of line manufacturing processes. We review recent advancements in perpendicular SOT-MRAM devices, emphasizing on material developments to enhance charge-spin conversion efficiency and large-scale device integration strategies. We also discuss the remaining challenges in achieving a single device with low switching current, reliable field free switching to unlock the full potential of SOT-MRAM technology.
Temporal signal processing with nonlocal optical metasurfaces
Authors: Cotrufo Michele , Esfahani Sedigheh , Korobkin Dmitriy , Alù Andrea 
Published: October 2024

AbstractNonlocal metasurfaces have recently enabled an ultra-compact, low-power and high-speed platform to perform analog image processing. While several computational tasks have been demonstrated based on this platform, most of the previous studies have focused only on spatial operations, such as spatial differentiation and edge detection. Here, we demonstrate that metasurfaces with temporal nonlocalities – that is, with a tailored dispersive response – can be used to implement time-domain signal processing in deeply subwavelength footprints. In particular, we experimentally demonstrate a passive metasurface performing first-order differentiation of input signals with high-fidelity and high-efficiency. We also show that this approach is prone to scalability and cascaded computation. Our work paves the way to a new generation of ultra-compact, passive devices for all-optical computation, with applications in neural networks and neuromorphic computing.
Small‐signal stability criterion of the PMSG‐based wind power delivery system via VSC‐HVDC
Authors: Li Qiao , Wu Linlin , Wang Xiao , Wang Haifeng 
Published: October 2024

AbstractThis paper presents an analytical examination of the small‐single stability (SSS) criterion of the permanent magnet synchronous generator (PMSG)‐based wind power delivery system via voltage source converter‐based high voltage direct current (VSC‐HVDC). First, a small‐signal model of the PMSG‐based WPDS is developed. Then, the SSS criterion, driven by the phase‐locked loop of the PMSG in the sub‐synchronous timescale, is derived. The derived SSS criterion provides analytical insights into why and how the loading condition, the grid connection, and the control parameters affect the system’s SSS. It is unambiguously revealed that increasing loading conditions of the PMSG or/and the grid connection of the WPDS to VSC‐HVDC shall bring about a higher risk of oscillatory instability. Hence, analytical derivation of the SSS criterion helps better understand the instability mechanism in the PMSG‐based WPDS via VSC‐HVDC. In addition, while the derivation of the SSS criterion presupposes identical dynamics among PMSGs, this derived criterion can still be approximately utilized to assess the SSS of the PMSG‐based WPDS via VSC‐HVDC, irrespective of whether the dynamics of the PMSGs are similar or different. Finally, the SSS criterion is demonstrated and evaluated through three examples of the PMSG‐based WPDS via VSC‐HVDC.
Triangular Fibrocartilage Complex (TFCC) – Anatomy, Imaging, and Classifications with Special Focus on the CUP Classification
Authors: Schmitt Rainer , Kunz Andreas Steven , Reidler Paul , Huflage Henner , Hesse Nina 
Published: October 2024

AbstractThe TFCC consists of several components whose functional significance has been recognized in detail in recent years. Existing classifications are partly incomplete. In addition, the TFCC requires specific and dedicated imaging techniques.This review describes the anatomy and pathoanatomy of the TFCC. The different types of TFCC lesions on MRI as well as MR and CT arthrography are explained and compared with the current literature. In addition, the novel CUP classification is presented and illustrated with image examples.Anatomically and functionally, the articular disc and radioulnar ligaments with their ulnar insertions and the inhomogeneously structured TFCC periphery must be differentiated. For accurate imaging, thin slices with high in-plane resolution and techniques to optimize contrast are required. Plain MRI is exclusively dependent on T2 contrast, while gadolinium-enhanced MRI offers the additional benefit of focal contrast enhancement, e.g., of fibrovascular repair tissue at the lesion site. However, the reference standard continues to be MR and CT arthrography, which should be used for focused indications. The CUP classification, which allows a comprehensive description and categorization of TFCC lesions, is presented and illustrated.