bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phyto-mediated metallic nano-architectures via Melissa officinalis L.: synthesis, characterization and biological properties
Authors: Fierascu Irina , Georgiev Milen I. , Ortan Alina , Fierascu Radu Claudiu , Avramescu Sorin Marius , Ionescu Daniela , Sutan Anca , Brinzan Alexandru , Ditu Lia Mara 
Published: September 2017

AbstractThe development of methods for obtaining new materials with antimicrobial properties, based on green chemistry principles has been a target of research over the past few years. The present paper describes the phyto-mediated synthesis of metallic nano-architectures (gold and silver) via an ethanolic extract of Melissa officinalis L. (obtained by accelerated solvent extraction). Different analytic methods were applied for the evaluation of the extract composition, as well as for the characterization of the phyto-synthesized materials. The cytogenotoxicity of the synthesized materials was evaluated by Allium cepa assay, while the antimicrobial activity was examined by applying both qualitative and quantitative methods. The results demonstrate the synthesis of silver nanoparticles (average diameter 13 nm) and gold nanoparticles (diameter of ca. 10 nm); the bi-metallic nanoparticles proved to have a core-shell flower-like structure, composed of smaller particles (ca. 8 nm). The Ag nanoparticles were found not active on nuclear DNA damage. The Au nanoparticles appeared nucleoprotective, but were aggressive in generating clastogenic aberrations in A. cepa root meristematic cells. Results of the antimicrobial assays show that silver nanoparticles were active against most of the tested strains, as the lowest MIC value being obtained against B. cereus (approx. 0.0015 mM).
Efficient Adsorption of Sulfamethazine onto Modified Activated Carbon: A Plausible Adsorption Mechanism
Authors: Liu Ying , Liu Xiaohui , Dong Wenping , Zhang Lingli , Kong Qiang , Wang Weiliang 
Published: September 2017

AbstractActivated carbon (AC) was modified by FeCl3. Batch experiments were carried out to evaluate the characteristics of equilibrium, kinetics and thermodynamics of Sulfamethazine adsorption onto original and modified AC. The results showed that Fe3+treatment changed the surface area, pore volume and surface zeta potential and increased the number of surface oxygenic functional groups. The adsorption of Sulfamethazine on modified activated carbon (MAC) was significantly improved. Isotherm test results revealed that the adsorption isotherms of Sulfamethazine on MAC fit the Freundlich, Langmuir and Temkin equations well. The maximum adsorption quantity of Sulfamethazine on MAC was 17.2414 mg/g at 25 °C. The adsorption kinetics of Sulfamethazine on AC and MAC can be characterized by the pseudo-second-order model. The adsorption process was affected by membrane diffusion, surface adsorption and internal diffusion. The adsorption quantities of Sulfamethazine first increased and then decreased for pH between 3 and 10. The removal efficiencies decreased with increasing temperature, which is favorable for adsorption at low temperature. It was also found that the mechanisms of adsorption included micropore capture and electrostatic, hydrogen bonding, π-π electron donor-acceptor (EDA) and coordination interactions as well as other interactions.
Structural colour of unary and binary colloidal crystals probed by scanning transmission X-ray microscopy and optical microscopy
Authors: Nho Hyun Woo , Yoon Tae Hyun 
Published: September 2017

AbstractColloidal crystals composed of micro- or nano- colloids have been investigated in various fields such as photonics due to their unique optical properties. Binary colloidal crystals have an outstanding potential for fine-tuning material properties by changing the components, concentration, or size of colloids. Because of their tunable optical, electrical, magnetic, and mechanical properties, those materials attracted great attention. However, it has been hard to elucidate internal structures without fluorescent labelling or cross-sectioning. Here, we demonstrate the structural analysis of not only unary but also binary colloidal crystals using scanning transmission x-ray microscopy and compare the results with colloidal structures and optical properties observed by optical microscopy. Based on the comparison of images obtained by these two methods, the domains of colloidal crystals consisting of different structures and colours were directly identified without any additional sample preparation. Therefore, it was possible to investigate the structural colours of local domains of unary and binary colloidal crystals such as the face centred cubic (FCC) structure with different orientations, that is FCC (111) and FCC (001), and hexagonal close-packed structure, HCP (0001).
Hα imaging observations of early-type galaxies from the ATLAS3D survey
Authors: Gavazzi G. , Consolandi G. , Pedraglio S. , Fossati M. , Fumagalli M. , Boselli A. 
Published: September 2017

Context. The traditional knowledge of the mechanisms that brought to the formation and evolution of early type galaxies (ETG) in a hierarchical Universe was challenged by the unexpected finding by ATLAS3D that 86% ETGs show signs of a fast rotating disk at their interior, implying an origin common to most spiral galaxies, followed by a quenching phase, while only a minority of the most massive systems are slow rotators and were likely to be the products of merger events.
Aims. Our aim is to improve our knowledge on the content and distribution of ionised hydrogen and their usage to form stars in a representative sample of ETGs for which the kinematics and detailed morphological classification were known from ATLAS3D.
Methods. Using narrow-band filters centered on the redshifted Hα line along with a broad-band (r-Gunn) filter to recover the stellar continuum, we observed or collected existing imaging observations for 147 ETG (including members of the Virgo cluster), representative of the whole ATLAS3D survey.
Results. 55 ETGs (37%) were detected in the Hα line above our detection threshold (HαEW ≤ −1 Å) and 21 harbour a strong source (HαEW ≤ −5 Å) .
Conclusions. The strong Hα emitters appear associated with mostly low-mass (M* ~ 1010 M⊙) S0 galaxies which contain conspicuous stellar and gaseous disks, harbouring significant star formation at their interior, including their nuclei. The weak Hα emitters are almost one order of magnitude more massive, contain gas-poor disks and harbour an AGN at their centers. Their emissivity is dominated by [NII] and does not imply star formation. The 92 undetected ETGs constitute the majority in our sample and are gas-free systems which lack a disk and exhibit passive spectra even in their nuclei. These pieces of evidence reinforce the conclusion of Cappellari (2016, ARA&A, 54, 597) that the evolution of ETGs followed the secular channel for the less massive systems and the dry merging channel for the most massive galaxies at the center of clusters of galaxies.
Toward an Information Infrastructure for Global Health Improvement
Authors: Friedman C. P. , Rubin J. C. , Sullivan K. J. 
Published: September 2017

Summary
Profound global challenges to individual and population health, alongside the opportunities to benefit from digital technology, have spawned the concept of the Learning Health System. Learning Health Systems (LHSs)--which can function at organizational, network, regional, and national levels of scale--have the capability of continuous data-driven self-study that promotes change and improvement. The LHS concept, which originated in the U.S. in 2007, is rapidly gaining attention around the world. LHSs require, but also transcend, the secondary use of health data. This paper describes the key features of LHSs, argues that effective and sustainable LHSs must be supported by infrastructures that allow them to function with economies of scale and scope, and describes the services that such infrastructures must provide. While it is relatively straightforward to describe LHSs, achieving them at the high level of capability necessary to promote significant health benefits will
require advancements in science and engineering, engaging the field of informatics among a wider range of disciplines. It also follows from this vision that LHSs cannot be built from an imposed blueprint; LHSs will more likely evolve from efforts at smaller scales that compose into larger systems.
Measuring Quality of Healthcare Outcomes in Type 2 Diabetes from Routine Data: a Seven-nation Survey Conducted by the IMIA Primary Health Care Working Group
Authors: Hinton W. , Liyanage H. , McGovern A. , Liaw S.-T. , Kuziemsky C. , Munro N. , de Lusignan S. 
Published: September 2017

Summary
Background: The Institute of Medicine framework defines six dimensions of quality for healthcare systems: (1) safety, (2) effectiveness, (3) patient centeredness, (4) timeliness of care, (5) efficiency, and (6) equity. Large health datasets provide an opportunity to assess quality in these areas.
Objective: To perform an international comparison of the measurability of the delivery of these aims, in people with type 2 diabetes mellitus (T2DM) from large datasets.
Method: We conducted a survey to assess healthcare outcomes data quality of existing databases and disseminated this through professional networks. We examined the data sources used to collect the data, frequency of data uploads, and data types used for identifying people with T2DM. We compared data completeness across the six areas of healthcare quality, using selected measures pertinent to T2DM management.
Results: We received 14 responses from seven countries (Australia, Canada, Italy, the Netherlands, Norway, Portugal, Turkey and the UK). Most databases reported frequent data uploads and would be capable of near real time analysis of healthcare quality.
The majority of recorded data related to safety (particularly medication adverse events) and treatment efficacy (glycaemic control and microvascular disease). Data potentially measuring equity was less well recorded. Recording levels were lowest for patient-centred care, timeliness of care, and system efficiency, with the majority of databases containing no data in these areas. Databases using primary care sources had higher data quality across all areas measured.
Conclusion: Data quality could be improved particularly in the areas of patient-centred care, timeliness, and efficiency. Primary care derived datasets may be most suited to healthcare quality assessment.
Artroplastia de suspensión dinámica de Scheker en el tratamiento de la artrosis trapeciometacarpiana
Authors: Novoa-Parra C. , Pérez-Correa J. , Pérez-Ortiz S. , Montaner-Alonso D. , Rodrigo-Pérez J. , Morales-Suarez-Varela M. 
Published: September 2017

Objetivo Evaluar los resultados clínicos y radiográficos de una serie de pacientes sometidos a una artroplastia de Scheker.
Material y Método Estudio descriptivo de 16 pacientes con artrosis TMC. Se valoró el estado clínico y funcional según el cuestionario DASH, la movilidad del pulgar según la escala de Kapandji y el dolor según la escala visual analógica (EVA). A nivel radiográfico, se cuantificó el colapso del espacio remanente tras la exéresis del trapecio.
Resultados La edad promedio de los pacientes fue 64,9 años, 81% fueron mujeres. El tiempo de seguimiento medio fue de 19 meses. La puntuación DASH preoperatoria fue de 67,68 puntos y postoperatoria 34,88 (p < 0.001). La puntuación EVA preoperatoria fue 8,44 y posoperatoria 1,69, (p < 0.001). La movilidad media del pulgar según Kapandji fue 7, (p < 0.001). Las fuerzas de puño, pinza de precisión y pinza lateral, pasaron de valores medios de 11,94, 3,41 y 3,46 en el preoperatorio, a valores medios de 1,25, 2,44 y 2,34 en el postoperatorio. En todos los casos se observó un cierto grado de colapso (31,38% de promedio) del espacio ocupado por el trapecio. El 87,5% de los pacientes se encontraban satisfechos con la cirugía y volverían a someterse a la misma.
Conclusión La artroplastia descrita por Scheker, es una alternativa quirúrgica que elimina el dolor y preserva la movilidad del pulgar. No evita el colapso del espacio dejado tras la exéresis del trapecio. No hubo diferencia en el resultado clínico entre los pacientes en los que se presentó un colapso leve o moderado.
Bleeding Complications and Mortality in Neonates Receiving Therapeutic Hypothermia and Extracorporeal Membrane Oxygenation
Authors: Lucke Ashley , Hagan Joseph , Kaiser Jeffrey , Cuevas Guaman Milenka 
Published: September 2017

Objective The objective of this study was to compare complications and mortality in neonates with hypoxic ischemic encephalopathy (HIE) on extracorporeal membrane oxygenation (ECMO) who did and did not receive therapeutic hypothermia (TH).
Study Design The Extracorporeal Life Support Organization registry was queried from 2005 to 2013 to identified infants with HIE. Infants ≤30 days of age with HIE on respiratory ECMO were included. Fisher's exact test and the Wilcoxon's rank-sum test were used to compare neonates with and without TH. Logistic regression was used to examine the association of TH with complications and mortality.
Results There were no difference between neonates with HIE who did (n = 78) and did not (n = 109) receive TH in demographics, severity of illness, complications, and mortality (p = 0.21).
Conclusion No differences in complications or mortality in neonates with HIE and respiratory ECMO were observed between those who did and did not receive TH. We suggest that for neonates requiring respiratory ECMO who also have HIE, TH is not contraindicated.
Lungenmetastasenchirurgie beim pulmonal metastasierten kolorektalen Karzinom
Authors: Macherey Sascha , Bruns Christiane , Alakus Hakan , Doerr Fabian , Heldwein Matthias , Quaas Alexander , Wahlers Thorsten , Hekmat Khosro 
Published: September 2017

Zusammenfassung
Hintergrund Patienten mit kolorektalem Karzinom sind häufig von Leber- und Lungenmetastasen betroffen. Neben Systemtherapien eignet sich für Patienten nach vollständiger Primärtumor- und potenzieller Lebermetastasenresektion die Lungenmetastasenchirurgie als therapeutisches Konzept.
Material und Methoden Es erfolgte eine systematische Literaturrecherche unter Berücksichtigung aller Studien, die ab dem 01. 01. 2010 publiziert worden sind. In die deskriptive Analyse wurden Studien eingeschlossen, die über mindestens 100 Patienten mit Lungenmetastasektomie berichteten und deren Operationszeitraum frühestens am 01. 01. 2000 begann. Aus den Studien wurden operative Daten, Überlebensdaten und Prognosefaktoren extrahiert.
Ergebnisse Elf Studienkohorten mit insgesamt 2891 Patienten konnten in die Analyse eingeschlossen werden. In den meisten Fällen wurde eine vollständige Resektion aller Metastasen erreicht und dabei subsegmentale den anatomischen Resektionsverfahren vorgezogen. Bei 2,3 – 18,2% der Patienten zeigten sich intrathorakale Lymphknotenmetastasen. Die postoperative Mortalität bewegte sich zwischen 0 und 0,5%. Der mediane Nachbeobachtungszeitraum erstreckte sich in den Fallserien von 27,5 bis zu 65,1 Monaten. Die Lungenmetastasenchirurgie war in den Studienkohorten mit 5-Jahres-Überlebensraten von 53 – 75,5% verbunden. Das 5-Jahres-Progressionsfreie-Überleben variierte zwischen 33 und 50,9%. Intrathorakale Rezidive traten in 25,2 – 42,9% der Patienten auf. Die Remetastasektomie resultierte in 5-Jahres-Überlebensraten von 49 – 75,5%. Die Analyse von Prognosemodellen offenbarte, dass die Metastasenanzahl, -größe und -verteilung eine untergeordnete prognostische Relevanz zu besitzen scheinen. Ein erhöhter CEA-Serumspiegel vor Metastasektomie und intrathorakale Lymphknotenmetastasen bedeuteten in mehreren Studien einen prognostischen Nachteil, nichtsdestotrotz können auch diese Patienten von der Lungenmetastasenchirurgie profitieren.
Schlussfolgerungen Für Patienten mit kolorektalem Karzinom und isolierter Lungen- oder kombinierter Leber- und Lungenmetastasierung sollte bei gewährleisteter Resektabilität die Metastasektomie die Therapie der Wahl sein. Die Lungenmetastasenchirurgie sollte durch eine Lymphknotenresektion ergänzt werden, um potenzielle Lymphknotenmetastasen zu entfernen. Patienten mit isolierten intrathorakalen Rezidiven sollte eine Remetastasektomie angeboten werden.
Fears and Concerns of Patients with Uterine Fibroids – a Survey of 807 Women
Authors: Knudsen Nina , Wernecke Klaus-D. , Siedentopf Friederike , David Matthias 
Published: September 2017

Abstract
Study questions What specific fears and concerns do patients with uterine fibroids have? How are these influenced by sociodemographic factors, duration of condition and level of knowledge among these women?
Methods Between January 2016 and January 2017 807 patients were consecutively surveyed at a university hospital speciality fibroid clinic using a two page locally developed and validated questionnaire focusing on fibroid-associated fears and concerns.
Results The questionnaire was completed by 730 women (90.5%) the majority of whom reported fears/concerns mainly with regards to treatment (need to treat/side-effects/hysterectomy) and the fibroids themselves (increasing size and number). Various parameters influenced the type and severity of fears: Young patients (< 40 years) had concerns particularly with regard to pregnancy/birthing while older patients (> 40 years) were more concerned about general health and significant blood loss. Time interval since diagnosis also affected fears with different concerns between patients with shorter duration of diagnosis (< 12 months) vs. longer duration (> 12 months). Overall only slight differences could be attributed to immigrant background. Higher level of education correlated with less anxiety. Proper information about fibroids relieved fears of malignant change in particular. Doctors and the internet were the most important sources of patient information.
Conclusions Due to the benign nature of uterine fibroids and their good treatability, fibroid-associated fears are generally unfounded. Precise knowledge of patient fears and concerns should be integrated into clinical care with targeted psychological support to help patients better understand their condition.
Prevalence and Trends in the Utilization of Gynecological Services by Adolescent Girls in Germany. Results of the German Health Survey for Children and Adolescents (KiGGS)
Authors: Krause Laura , Seeling Stefanie , Prütz Franziska , Rommel Alexander 
Published: September 2017

AbstractThere is only limited data available on the utilization of gynecological services in Germany. Based on data from the German Health Survey for Children and Adolescents (KiGGS) of the Robert Koch Institute, a survey carried out across all of Germany, this study aimed to examine the utilization of gynecological services by girls in Germany. Data from the KiGGS Wave 1 survey (2009 – 2012) was used to analyze the factors which affect utilization. The KiGGS baseline study (2003 – 2006) was used to analyze trends. The database consisted of a subsample from the KiGGS Wave 1 survey (n = 2575), the initial follow-up survey conducted by telephone after the baseline study. Data are shown as prevalence and mean with 95% confidence intervals. Correlations with selected influencing factors were calculated using multivariate logistic regression models. Differences between study populations were considered significant if p < 0.05. At the time of the KiGGS Wave 1 survey, 53.9% of girls aged 14 to 17 years had visited a gynecologist at least once. This percentage increased significantly with each additional year of life. For 61.9% of 17-year-old girls who had previously visited a gynecologist at least once, the first visit to a gynecologist occurred at the age of 15 or 16 years. Growing up with siblings was associated with a lower prevalence of utilization, while middle socioeconomic status, risky alcohol consumption and daily consumption of tobacco, and the utilization of general medical services were associated with a higher 12-month prevalence for the utilization of gynecological services. The utilization of gynecological services has increased significantly compared to the KiGGS baseline survey. Among girls there is a high need for information on issues of sexual health. Gynecologists are important but they are not the only port of call. Information needs should be covered as part of a coordinated approach which includes the involvement of all relevant stakeholders. Initiatives such as the WHO Action Plan for Sexual and Reproductive Health and its recommendations should be incorporated.
Occurrence of an Intersexual Pacific Spadenose Shark Scoliodon macrorhynchos from the Southern Taiwan Strait
Authors: Zhao Yu , Chen Mingru , Jiang Chengpu , Yang Shengyun , Xiao Jiamei 
Published: September 2017

Abstract
An intersexual specimen of Pacific Spadenose Shark Scoliodon macrorhynchos was found in the southern Taiwan Strait. It exhibited fully calcified claspers as well as bilateral ovotestes and reproductive tracts of both sexes. Histological analysis of its left ovotestis showed that it contained viable germ cells of both sexes, which allowed potential functionality as either sex physiologically. This specimen represents the first reported case of intersexuality in the genus Scoliodon and is also a rare record of intersexuality in elasmobranchs.
A stroboscopic light source for experiments in mechanics
Authors: Mayer V V , Varaksina E I 
Published: September 2017

Abstract
We propose to attach a small stroboscopic light source to a moving object and connect the source to a pulse generator with the help of insulated thin flexible multi-cored wires. Students can assemble such a device independently in a school laboratory. The device can be used to obtain trajectories with time marks in students’ research projects in mechanics. In the paper we give an example of the application of stroboscopic photography in a demonstration experiment devoted to inertia.