bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fault estimation and tolerant control for discrete‐time switched systems with sojourn probabilities
Authors: Sakthivel Rathinasamy , Joby Maya , Santra Srimanta , Ren Yong 
Published: August 2017

SummaryThis paper addresses the issue of fault estimation and accommodation for a discrete‐time switched system with actuator faults. Here, we assume that the sojourn probabilities are known a priori. By using the reduced‐order observer method, the sojourn probability approach, and the Lyapunov technique, a fault estimation algorithm is obtained for the considered system. The main objective of this work is to design a dynamic output feedback fault‐tolerant controller based on the obtained fault estimation information such that the closed‐loop discrete‐time switched system with available sojourn probabilities is robustly mean‐square stable and satisfies a prescribed mixed
and passivity disturbance attenuation level in the presence of actuator faults. More precisely, a dynamic output feedback fault‐tolerant controller is established in terms of linear matrix inequalities. Finally, numerical examples are provided to illustrate the usefulness and effectiveness of the proposed design technique.
Waterborne Nonfluorinated Superhydrophobic Coatings with Exceptional Mechanical Durability Based on Natural Nanorods
Authors: Zhang Junping , Gao Ziqian , Li Lingxiao , Li Bucheng , Sun Hanxue 
Published: August 2017

AbstractPractical applications of superhydrophobic coatings are hindered by some issues, such as harmful chemicals, low mechanical durability, complicated methods, and expensive building blocks, etc. This study reports preparation of waterborne nonfluorinated superhydrophobic coatings with exceptional mechanical durability based on natural nanorods, palygorskite (PAL). A polyurethane (PU) aqueous solution and the homogeneous methyl polysiloxane‐modified PAL (PAL@M‐POS) suspension composed of methyltrimethoxysilane and the PAL nanorods in water are layer‐by‐layer spray‐coated onto glass slides for two times with PU as the adhesive layer. The PAL@M‐POS suspensions and the superhydrophobic PU/PAL@M‐POS coatings are studied using various analytical techniques. The influences of PAL and methyltrimethoxysilane on microstructure, wettability, and mechanical durability of the coatings are also investigated. The PU/PAL@M‐POS coatings feature high water contact angle (157.9°), low sliding angle (7.2°), and exceptional mechanical durability against sandpaper abrasion for 80 m and peeling with adhesive tape for 100 cycles. The mechanism behind the high mechanical durability is proposed. Also, the totally green method is simple, low‐cost, scalable, and applicable onto various substrates, which have paved the way for practical applications of the durable superhydrophobic coatings. This work provides a new avenue for the fabrication of waterborne, nonfluorinated, and mechanically durable superhydrophobic coatings using abundant natural nanomaterials.
Methacrylate based side chain liquid crystalline polymers with pendant cholesterol group: Preparation and investigation of electrical conductivity mechanism
Authors: Doganci Erdinc , Cakirlar Cigdem , Bayir Sumeyra , Yilmaz Faruk , Yasin Muhammad 
Published: August 2017

ABSTRACTMethacrylate based side‐chain liquid crystalline polymers (SCLCP) bearing cholesterol pendant moieties with various lengths of aliphatic spacer were synthesized and their electrical conductivity mechanism was studied for their possible applications in elastic microelectronic devices. All the polymers exhibited liquid crystalline behavior of broken focal‐conic fan texture of smectic phase. The dielectric properties of polymers were investigated by impedance spectroscopic technique in the frequency range of 100 Hz to 15 MHz at room temperature. Alternating current (AC) conductivity (
) of the liquid crystalline polymeric films was observed to vary with angular frequency, ω as ωS with s < 2. Detailed conductivity analysis revealed that the conductivity of the polymeric films follows quantum mechanical tunneling and correlated barrier hoping conductivity mechanisms at low frequency regime, whereas it obeys super linear power law and direct current conductivity mechanisms at high frequency region. The investigation of the SCLC polymeric films helped to propose a model system for their possible potential applications. In the light of this study, the SCLC polymers will be employed as the gate insulator for organic field effect transistor applications, such as large area flexible arrays or as other advanced microelectronic devices that have superior performance. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45207.
Effect of resin modifiers on the structural properties of epoxy resins
Authors: Kregl Laura , Wallner Gernot M. , Lang Reinhold W. , Mayrhofer Gerhard 
Published: August 2017

ABSTRACTThermomechanical, mechanical and fracture mechanical properties of modified epoxy resins with two different modifiers are investigated. Carboxyl‐terminated butadiene‐acrylonitrile (CTBN) is used as toughening agent and hexanediole diglycidyl ether (HDDGE) as reactive diluent. Both modifiers are admixed in contents from 0 up to 100 phr (parts per hundred resin) and exhibit flexibilizing and toughening qualities. The glass transition temperature is strongly depressed by the admixed reactive diluent, whereas the tensile modulus exhibits greater dependency on the toughening agent contents. The tensile strength and strain at break values are higher for the formulations with diluent compared to resins with toughening agent. Up to a content of 45 phr both modified systems exhibit comparable fracture toughness values. Only the toughened systems comprise increasing values for modifier amounts higher than 45 phr. For the formulation with both modifiers (toughening agent and diluent) a significantly higher toughness but a reduced glass transition temperature was obtained. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45348.
Suboptimal Output Consensus for Time‐Delayed Singular Multi‐Agent Systems
Authors: Wang Jiajing , He Ming , Xi Jianxiang , Yang Xiaogang 
Published: August 2017

AbstractThe current paper investigates guaranteed‐cost output consensus analysis and design problems for high‐order linear time‐invariant singular multi‐agent systems with constant time delays, which can realize suboptimal output consensus control. Firstly, a new output consensus protocol with a suboptimal index and a single delay is proposed to realize the tradeoff design between output consensus regulation performances and control energy consumptions. Then, sufficient conditions for guaranteed‐cost output consensus and consensualization are derived in terms of linear matrix inequalities by a combined tool from the Lyapunov‐Krasovskii approach and the free‐weighting matrix technique, respectively, and the output consensus function is determined on the basis of the First Equivalent Form. Finally, a numerical example is performed to demonstrate the effectiveness and conservativeness of theoretical results.
Distributed Consensus of Third‐order Multi‐agent Systems with Communication Delay
Authors: Hou Wenying , Fu Minyue , Zhang Huanshui 
Published: August 2017

AbstractThis paper studies the consensus problem for a class of general third‐order multi‐agent systems on an undirected connected network. By employing a variables transformation, the consensus control problem can be turned into a asymptotical stability problem. Then we present a necessary and sufficient condition for guaranteeing consensus by using Routh‐Hurwitz stability criterion. And this result can be applied to a special case of third‐order integrator systems. Also we will present a tolerable communication time delay for third‐order integrator systems under the assumption that multi‐agent systems can reach consensus without communication delay.
Ratiometric fluorescence detection of superoxide anion based on AuNPs‐BSA@Tb/GMP nanoscale coordination polymers
Authors: Liu Nan , Hao Juan , Cai Keying , Zeng Mulan , Huang Zhenzhong , Chen Lili , Peng Bingxian , Li Ping , Wang Li , Song Yonghai 
Published: August 2017

AbstractA novel ratiometric fluorescence nanosensor for superoxide anion (O2•−) detection was designed with gold nanoparticles‐bovine serum albumin (AuNPs‐BSA)@terbium/guanosine monophosphate disodium (Tb/GMP) nanoscale coordination polymers (NCPs) (AuNPs‐BSA@Tb/GMP NCPs). The abundant hydroxyl and amino groups of AuNPs‐BSA acted as binding points for the self‐assembly of Tb3+ and GMP to form core‐shell AuNPs‐BSA@Tb/GMP NCP nanosensors. The obtained probe exhibited the characteristic fluorescence emission of both AuNPs‐BSA and Tb/GMP NCPs. The AuNPs‐BSA not only acted as a template to accelerate the growth of Tb/GMP NCPs, but also could be used as the reference fluorescence for the detection of O2•−. The resulting AuNPs‐BSA@Tb/GMP NCP ratiometric fluorescence nanosensor for the detection of O2•− demonstrated high sensitivity and selectivity with a wide linear response range (14 nM–10 μM) and a low detection limit (4.7 nM).
Shorter telomere length increases age‐related tumor risks in von Hippel‐Lindau disease patients
Authors: Wang Jiang‐Yi , Peng Shuang‐He , Ning Xiang‐Hui , Li Teng , Liu Sheng‐Jie , Liu Jia‐Yuan , Hong Bao‐An , Qi Nie‐Nie , Peng Xiang , Zhou Bo‐Wen , Zhang Jiu‐Feng , Cai Lin , Gong Kan 
Published: August 2017

AbstractVon Hippel‐Lindau (VHL) disease is a rare autosomal dominant cancer syndrome caused by alterations of VHL gene. Patients are predisposed to develop pheochromocytomas and solid or cystic tumors of the central nervous system, kidney, pancreas, and retina. Remarkable phenotypic heterogeneity exits in organ involvement and tumor onset age between and within VHL families. However, no reliable markers have been found to predict the age‐related tumor risks in VHL patients. A large Chinese cohort composed of 300 VHL patients and 92 healthy family controls was enrolled in our study. Blood relative telomere length was measured in 184 patients and all the controls available for genomic DNA samples. Age‐related risks for the five major VHL‐associated tumors were evaluated using Kaplan–Meier plots and Cox regression analysis. Differences in clinical phenotype were observed between Chinese cohort and the United Kingdom cohort. VHL patients showed significantly shorter telomere length than healthy family controls(P = 0.0183), and a positive correlation was found between telomere length and onset age of the five major tumors, respectively. Moreover, patients in the shorter telomere group (age‐adjusted telomere length ≤ 0.44) suffered higher age‐related risks for VHL‐associated central nervous system hemangioblastomas (HR: 1.879, P = 0.004), renal cell carcinoma (HR: 2.126, P = 0.002) and pancreatic cyst and neuroendocrine tumors (HR: 2.093, P = 0.001). These results indicate that blood shorter telomere length is a new biomarker for age‐related tumor risks in VHL patients, which will be crucial to genetic counseling and future research about the role of telomere shortening in the pathogenesis of VHL‐associated tumors.
Racial disparities in the utilization of preventive health services among older women with early‐stage endometrial cancer enrolled in Medicare
Authors: Martin Jovana Y. , Schiff Melissa A. , Weiss Noel S. , Urban Renata R. 
Published: August 2017

AbstractTo assess differences in the receipt of preventive health services by race/ethnicity among older women with endometrial cancer enrolled in Medicare, we conducted a retrospective population‐based cohort study of women diagnosed with endometrial cancer from 2001 to 2011 in the Surveillance Epidemiology and End Results (SEER)‐Medicare database. Women with stage I or II endometrial cancer of epithelial origin were included. The exposure was race/ethnicity (Non‐Hispanic [NH] White, NH Black, Hispanic, and NH Asian/Pacific Islander [PI]). The services examined were receipt of influenza vaccination and screening tests for diabetes mellitus, hyperlipidemia, and breast cancer. We used multivariate logistic regression to estimate odds ratios with 95% confidence intervals (CI) adjusted for age, region, and year of diagnosis. A total of 13,054 women were included. In the 2 years after diagnosis, receipt of any influenza vaccine ranged from 45% among NH Black women to 67% among NH White women; receipt of a mammogram ranged from 65% among NH Black women to 74% among NH White women. Relative to NH White women, NH Black women had a lower likelihood of receiving both influenza vaccination (adjusted odds ratio [aOR] 0.40, 95% CI 0.33–0.44) and screening mammography (aOR 0.64, 95% CI 0.52–0.79). Hispanic women also were less likely to receive influenza vaccination than NH White women (aOR 0.61, 95% CI 0.51–0.72). There were no significant differences across racial groups for diabetes or cholesterol screening services. Among older women with early‐stage endometrial cancer, racial disparities exist in the utilization of some preventive services.
First follow‐up radiographic response is one of the predictors of local tumor progression and radiation necrosis after stereotactic radiosurgery for brain metastases
Authors: Sharma Mayur , Jia Xuefei , Ahluwalia Manmeet , Barnett Gene H. , Vogelbaum Michael A. , Chao Samuel T. , Suh John H. , Murphy Erin S. , Yu Jennifer S. , Angelov Lilyana , Mohammadi Alireza M. 
Published: August 2017

AbstractLocal progression (LP) and radiation necrosis (RN) occur in >20% of cases following stereotactic radiosurgery (SRS) for brain metastases (BM). Expected outcomes following SRS for BM include tumor control/shrinkage, local progression and radiation necrosis. 1427 patients with 4283 BM lesions were treated using SRS at Cleveland Clinic from 2000 to 2012. Clinical, imaging and radiosurgery data were collected from the database. Local tumor progression and RN were the primary end points and correlated with patient and tumor‐related variables. 5.7% of lesions developed radiographic RN and 3.6% showed local progression at 6 months. Absence of new extracranial metastasis (P < 0.001), response to SRS at first follow‐up scan (local progression versus stable size (P < 0.001), partial resolution versus complete resolution at first follow up [P = 0.009]), prior SRS to the same lesion (P < 0.001), IDL% (≤55; P < 0.001), maximum tumor diameter (>0.9 cm; P < 0.001) and MD/PD gradient index (≤1.8, P < 0.001) were independent predictors of high risk of local tumor progression. Absence of systemic metastases (P = 0.029), good neurological function at 1st follow‐up (P ≤ 0.001), no prior SRS to other lesion (P = 0.024), low conformity index (≤1.9) (P = 0.009), large maximum target diameter (>0.9 cm) (P = 0.003) and response to SRS (tumor progression vs. stable size following SRS [P < 0.001]) were independent predictors of high risk of radiographic RN. Complete tumor response at first follow‐up, maximum tumor diameter <0.9 cm, tumor volume <2.4 cc and no prior SRS to the index lesion are good prognostic factors with reduced risk of LP following SRS. Complete tumor response to SRS, poor neurological function at first follow‐up, prior SRS to other lesions and high conformity index are favorable factors for not developing RN. Stable or partial response at first follow‐up after SRS have same impact on local progression and RN compared to those with complete resolution or progression.
Development of Harlequin Syndrome following placement of thoracic epidural anesthesia in a pediatric patient undergoing Nuss procedure
Authors: Lefevre Ashley , Schnepper Gregory 
Published: August 2017

Key Clinical MessageWe report the development of Harlequin Syndrome following thoracic epidural placement in a pediatric patient. Unilateral facial flushing with contralateral pallor and anhidrosis is the clinical presentation. This syndrome is typically benign. When related to regional anesthesia, treatment involves reducing the local anesthetic infusion or stopping it altogether.
Semisupervised local preserving embedding algorithm based on maximum margin criterion for large‐scale data streams
Authors: Tan Chao , Ji Genlin 
Published: August 2017

SummaryIn the field of machine learning, feature extraction is one of the most important preprocessing in data classification for its effectiveness, and now it has attracted much extensive attention for large‐scale data stream preprocessing step, especially in the era of big data. Motivated by the advantages of unsupervised and supervised feature extraction, which are two desirable and promising characteristics for dimension reduction, a new semisupervised local preserving embedding algorithm based on maximum margin criterion (SLPE/MMC) is proposed in this paper. First, the objective functions of maximum margin criterion (MMC) and neighborhood preserving embedding (NPE) are combined to get the first objective function of SLPE/MMC. Then, in order to overcome the out‐of‐sample problem, a linear transformation is introduced to construct the second objective function. At last, the whole optimal objective function is constructed by combing the two objective functions together. The proposed algorithm has effectively taken advantage of the sample's supervised information and keeps the geometry structure and the class discrimination information of the manifold. Experiments on face datasets Yale, CMU PIE, and AR datasets are performed to evaluate the classification accuracy of SLPE/MMC. The experimental results and time complexity comparisons have demonstrated the effectiveness of the proposed method.
Catalyst Particle Density Controls Hydrocarbon Product Selectivity in CO2 Electroreduction on CuOx
Authors: Wang Xingli , Varela Ana Sofia , Bergmann Arno , Kühl Stefanie , Strasser Peter 
Published: August 2017

AbstractA key challenge of the carbon dioxide electroreduction (CO2RR) on Cu‐based nanoparticles is its low faradic selectivity toward higher‐value products such as ethylene. Here, we demonstrate a facile method for tuning the hydrocarbon selectivities on CuOx nanoparticle ensembles by varying the nanoparticle areal density. The sensitive dependence of the experimental ethylene selectivity on catalyst particle areal density is attributed to a diffusional interparticle coupling that controls the de‐ and re‐adsorption of CO and thus the effective coverage of COad intermediates. Thus, higher areal density constitutes dynamically favored conditions for CO re‐adsorption and *CO dimerization leading to ethylene formation independent of pH and applied overpotential.
Synergistic Interaction of Matricaria Chamomilla Extract with Diclofenac and Indomethacin on Carrageenan‐Induced Paw Inflammation in Rats
Authors: Ortiz Mario I. , Cariño‐Cortés Raquel , Ponce‐Monter Héctor A. , González‐García Martha P. , Castañeda‐Hernández Gilberto , Salinas‐Caballero Mireya 
Published: August 2017

ABSTRACT

Preclinical Research

The coadministration of non‐steroidal anti‐inflammatory drugs (NSAIDs) with medicinal plant extracts may increase anti‐inflammatory activity, thus permitting the use of lower NSAID doses and limiting the side effects. The aim of this study was to explore the interactions between an ethanolic extract of M. chamomilla extract (MCE) with two NSAIDs, diclofenac and indomethacin on carrageenan‐induced paw inflammation and gastric injury in rats. Diclofenac, indomethacin and MCE, or combinations with MCE produced an anti‐inflammatory effect. Effective dose (ED) values were estimated for the individual drugs, and isobolograms were constructed. The final experimental ED values were 483.7 mg/kg for diclofenac + MCE combination, and 212.6 mg/kg for indomethacin + MCE. These values were lower (p < 0.05) than the theoretical ED values (1186.9 mg/kg for diclofenac + MCE combination, and 1183.8 mg/kg for indomethacin + MCE). These data suggest that the interactions between NSAIDs and MCE that mediate the anti‐inflammatory effects at the systemic level are synergistic and may have therapeutic advantages for the clinical treatment of inflammatory processes. Drug Dev Res 78 : 360‐367, 2017. © 2017 Wiley Periodicals, Inc.
A multi‐analyte approach to help in assessing the severity of acute poisonings – Development and validation of a fast LC–MS/MS quantification approach for 45 drugs and their relevant metabolites with one‐point calibration
Authors: Michely Julian A. , Maurer Hans H. 
Published: August 2017

AbstractDiagnosis, monitoring of the efficiency of detoxification, and estimating the prognosis of acute poisonings are important tasks in emergency toxicology. Comprehensive screening and quantification of relevant substances by gas chromatography–mass spectrometry (GC–MS) or liquid chromatography–mass spectrometry (LC–MS) help in assessing the severity of most acute poisonings. Turnaround time for such analyses must be short enough to impact on clinical decisions. Therefore, a multi‐analyte LC–MS/MS approach with a 5‐minute gradient was developed and validated for 45 drugs and their active metabolites as a complement to an existing GC–MS approach using the same liquid–liquid extraction. The determination ranges were defined by quality control samples of low and high, representing concentrations from low therapeutic to highly toxic levels. To shorten the turnaround time, one‐point calibration was used. Validation showed low matrix effects and ionization effects of co‐eluting analytes thanks to APCI source as well as sufficient recoveries, precisions, and selectivities. For accuracy, 32 of the 45 compounds fulfilled the criteria for quantification in lower therapeutic and 41 in overdosed and toxic concentrations, considering limits of ±30% deviation. The reuse of the processed calibrator for a period of 30 days was possible for 32 compounds, showing sufficient stability at 8°C. In addition, analysis of authentic blood samples showed the applicability and yielded drug levels, which were comparable to those determined by fully validated therapeutic drug monitoring methods. In conclusion, the present approach in combination with the GC–MS approach should provide sufficient support for clinical assessment of the severity of poisonings with 68 compounds in an acceptable turnaround time.