bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Modified Iterative Closest Point Algorithm for 3D Point Cloud Registration
Authors: Marani Roberto , Renò Vito , Nitti Massimiliano , D'Orazio Tiziana , Stella Ettore 
Published: January 2016

AbstractIn this article, an accurate method for the registration of point clouds returned by a 3D rangefinder is presented. The method modifies the well‐known iterative closest point (ICP) algorithm by introducing the concept of deletion mask. This term is defined starting from virtual scans of the reconstructed surfaces and using inconsistencies between measurements. In this way, spatial regions of implicit ambiguities, due to edge effects or systematical errors of the rangefinder, are automatically found. Several experiments are performed to compare the proposed method with three ICP variants. Results prove the capability of deletion masks to aid the point cloud registration, lowering the errors of the other ICP variants, regardless the presence of artifacts caused by small changes of the sensor view‐point and changes of the environment.
Rituximab for recurrent IgA nephropathy in kidney transplantation: A report of three cases and proposed mechanisms
Authors: Chancharoenthana Wiwat , Townamchai Natavudh , Leelahavanichkul Asada , Wattanatorn Salin , Kanjanabuch Talerngsak , Avihingsanon Yingyos , Praditpornsilpa Kearkiat , Eiam‐Ong Somchai 
Published: January 2016

AbstractAimRecurrent IgA nephropathy (IgAN) is a common recurrent glomerular disease after kidney transplantation. Recurrent IgAN, in particular, with crescent formation or endocapillary proliferation might result in kidney allograft loss. However, the current treatment options of recurrent IgAN are conflicting.MethodsWe have reported three kidney‐transplanted recipients with biopsy‐proven recurrent IgAN treated with four consecutive months of rituximab at the dose of 375 mg/1.73m2 without corticosteroids.ResultsAt median follow‐up 20 months following rituximab administration, all three recipients demonstrated decrease in proteinuria severity, slow disease progression with a well‐tolerated condition. This therapeutic effect is most probably mediated by the B cell depletion.ConclusionOur three case reports suggest that the disease severity of recurrent IgAN with endocapillary proliferation regardless of crescent formation can be minimized by the four doses of monthly rituximab regimen.
Drought and flooding have distinct effects on herbivore‐induced responses and resistance inSolanum dulcamara
Authors: Nguyen Duy , D'Agostino Nunzio , Tytgat Tom O. G. , Sun Pulu , Lortzing Tobias , Visser Eric J. W. , Cristescu Simona M. , Steppuhn Anke , Mariani Celestina , van Dam Nicole M. , Rieu Ivo 
Published: January 2016

AbstractIn the field, biotic and abiotic stresses frequently co‐occur. As a consequence, common molecular signalling pathways governing adaptive responses to individual stresses can interact, resulting in compromised phenotypes. How plant signalling pathways interact under combined stresses is poorly understood. To assess this, we studied the consequence of drought and soil flooding on resistance ofSolanum dulcamaratoSpodoptera exiguaand their effects on hormonal and transcriptomic profiles. The results showed thatS. exigualarvae performed less well on drought‐stressed plants than on well‐watered and flooded plants. Both drought and insect feeding increased abscisic acid and jasmonic acid (JA) levels, whereas flooding did not induce JA accumulation. RNA sequencing analyses corroborated this pattern: drought and herbivory induced many biological processes that were repressed by flooding. When applied in combination, drought and herbivory had an additive effect on specific processes involved in secondary metabolism and defence responses, including protease inhibitor activity. In conclusion, drought and flooding have distinct effects on herbivore‐induced responses and resistance. Especially, the interaction between abscisic acid and JA signalling may be important to optimize plant responses to combined drought and insect herbivory, making drought‐stressed plants more resistant to insects than well‐watered and flooded plants.
Childhood Pemphigus Foliaceus with Exclusive Immunoglobulin G Autoantibodies to Desmocollins
Authors: Geller Shamir , Gat Andrea , Harel Avikam , Mashiah Jacob , Zeeli Tal , Eming Rüdiger , Ishii Norito , Hertl Michael , Hashimoto Takashi , Sprecher Eli 
Published: January 2016

AbstractPemphigus refers to a group of potentially fatal blistering skin diseases that are often due to the deleterious effects of autoantibodies directed against desmosomal antigens. Although desmogleins have been mainly implicated as autoantigens in pemphigus, a steadily growing body of evidence suggests that other desmosomal proteins may be causally involved as well. Antibodies directed against desmocollin‐3 have been shown to play a direct role in the pathogenesis of several types of pemphigus. Here we describe the case of a child with localized pemphigus foliaceus and immunoglobulin G (IgG) reactivity exclusively directed to desmocollins. The present report suggests that autoantibodies against nondesmoglein antigens may play a role in the pathogenesis of superficial pemphigus, in addition to pemphigus vulgaris, paraneoplastic pemphigus, and IgA pemphigus.
Rhabdomyomatous Mesenchymal Hamartoma: A Deep Subcutaneous Lesion in the Sternoclavicular Area
Authors: Orozco‐Covarrubias Luz , Carrasco‐Daza Daniel , Diaz‐Noriega Ana , Lara‐Mendoza Leticia , Ruiz‐Maldonado Ramon 
Published: January 2016

AbstractCutaneous rhabdomyomatous mesenchymal hamartoma (RMH) is a rare benign tumor composed of two or more types of mesenchymal‐derived cells. RMHs are generally sporadic and independent, but they can be associated with congenital abnormalities. We report a subcutaneous case of RMH in the sternoclavicular area with two recurrences after complete surgical excision. The course is variable and can range from spontaneous resolution to repeated recurrences.
Self‐Regulation and Power: How Self‐Regulatory Failures Can Enhance Social Power
Authors: McIntyre Jason C. , von Hippel William , Barlow Fiona Kate 
Published: January 2016

AbstractLow self‐control is often associated with poor life outcomes. Here, we propose that self‐control failures may also provide social benefits by signaling and maintaining power. We identify several pathways by which reduced self‐control can assist in ascending social hierarchies. First, the self‐enhancing tendencies adopted by people with low self‐control may contribute to making positive first impressions and advertising power to new acquaintances. The direct and disinhibited communication styles that stem from self‐control failures may also enhance power and lubricate difficult social interactions. Disinhibited aggression can help people maintain and acquire material resources and establish dominance over rivals. Finally, the parallels between the behavior of people with low self‐control and people with power (e.g., self‐enhancement, disinhibition, approach‐orientation, aggression) suggest that people with impaired self‐control will be perceived as more powerful than people with intact self‐control. Evidence for these propositions and directions for future research are discussed.
Exploring the Toolkit of Emotion: What Do Sadness and Anger Do for Us?
Authors: Lench Heather C. , Tibbett Thomas P. , Bench Shane W. 
Published: January 2016

AbstractWhat do negative emotions do for people? We present a framework that defines the function of emotions as the degree to which discrete emotions result in better outcomes in particular types of situations. Focusing on sadness and anger, we review evidence related to the situations that elicit these emotions; the cognitive, physiological, and behavioral changes associated with the emotions; and the extent to which these changes result in demonstrably better outcomes in the type of situation that elicits the emotion. Sadness is elicited by perceived goal loss without possibility of restoration given current abilities and is associated with deliberative reasoning, reduced physiological activity, and behavioral expression. There is preliminary evidence suggesting that sadness can permit coping with loss, and that expression of sadness can recruit others to assist in goal attainment. Anger is elicited by perceived goal loss that can be prevented if an obstacle is overcome and is associated with heuristic reasoning, increased physiological activity, and behavioral expression. There is evidence that expression of anger prompts others to remove themselves as obstacles, and preliminary evidence that anger can promote overcoming obstacles and goal attainment. Like precision tools, specific emotions are best utilized to resolve particular problems.
Toward the Desegregation of Thought and Affect in Psychological Theorizing
Authors: Falmagne Rachel Joffe 
Published: January 2016

AbstractThis article interrogates the historical segregation of thought and affect in psychological theorizing. I note how, across a range of theoretical approaches to the study of thinking, the relations between thought and affect have been either negated or ignored or underemphasized. In the context of the recent ‘turn to affect’ in the social sciences, which has been seen as offering a new paradigm for conceptualizing social and psychological phenomena, this elision is all the more striking, and a selective overview of current writings illustrative of this literature is presented. Yet, reciprocally, it is noteworthy that the ‘turn to affect’ literature has not addressed the relation between affect and thought, and hence that it contributes to the theoretical segregation that I argue is problematic. I then discuss some recent proposals within psychology that, in each of their specific ways, dissolve the theoretical dualism between thinking and affect, and offer an integrative reformulation that synthesizes the affective, intellectual, and psychosocial constituents of thought, as well as some works outside of psychology that can be viewed as illustrating the fusion of thought and affect. I argue for an approach that recognizes the biographical intertwining of the affective and intellectual life of the epistemic agent and the way in which both are shaped by processes of social constitution and by transgenerational influences.
An Animal Just Like Me: The Importance of Preserving the Identities of Companion‐Animal Owners in Disaster Contexts
Authors: Trigg Joshua , Thompson Kirrilly , Smith Bradley , Bennett Pauleen 
Published: January 2016

AbstractThe widespread tendency of modern‐day pet owners to self‐identify with their companion animals psychologically, symbolically and relationally demonstrates how the constructed identities of animal and owner are strongly linked. This becomes particularly apparent during natural disasters. In this review, the new concept of the pet‐owning self is discussed in relation to three self‐psychology perspectives: self‐extension, symbolic interactionism and selfobject relations. We purposefully depart from the realm of attachment theory to argue that these three epistemological approaches to self‐identity, although related, warrant closer examination. Although we discuss them in relation to disaster contexts, the concept of the pet‐owning self remains widely applicable. We argue for the importance of acknowledging the powerful intersubjectivity inherent to pet keeping, the inseparability of perceived pet identity from owners' experiences of the self and that preserving the cohesion of the two is an essential consideration for owners' psychological wellbeing when managing the integrated pet/owner in the face of risks posed by disaster and other hazards. Future research opportunities and implications are then discussed in the context of social identity theory.
Molecular detection of Crimean–Congo haemorrhagic fever virus in ticks collected from infested livestock populations in a New Endemic Area, South of Iran
Authors: Farhadpour F. , Telmadarraiy Z. , Chinikar S. , Akbarzadeh K. , Moemenbellah‐Fard M. D. , Faghihi F. , Fakoorziba M. R. , Jalali T. , Mostafavi E. , Shahhosseini N. , Mohammadian M. 
Published: January 2016

AbstractObjectiveCrimean–Congo haemorrhagic fever (CCHF) is a viral zoonotic disease with potentially fatal systemic effects on man. We aimed to determine the presence of CCHF virus among collected ticks from domestic livestock from October 2012 to September 2013.MethodsA total of 1245 hard and soft ticks were collected from naturally infested ruminants in Marvdasht County, Fars Province, south of Iran. Nine tick species and one unidentified species in four disparate genera were detected. A total of 200 ticks were randomly selected and analysed by reverse transcription–polymerase chain reaction (RT‐PCR) for the presence of CCHF virus genome.ResultsThe viral genome was detected in 4.5% (9 samples) of the studied tick population. The infected ticks belonged to the species of Hyalomma marginatum‚ Hyalomma anatolicum and Rhipicephalus sanguineus. The viruses detected in these three tick species were clustered in the same lineage as Matin and SR3 strains in Pakistan and some other Iranian strains. These results indicate that the ticks were wildly infected with a genetically closely related CCHF virus in the region.ConclusionRegular controls and monitoring of livestock to reduce the dispersion of ticks and providing information to those involved in high‐risk occupations are urgently required.
Sensor Signal Limitations in Wheel Rotational Kinematics Estimation Model
Authors: Paldan Jesse R. , Gray Jeremy P. , Vantsevich Vladimir V. 
Published: January 2016

Wheel encoders play an important role in providing information about rotational kinematics of vehicle wheels. The sensor signals are utilized in critical vehicle systems responsible for vehicle safety, traction and braking performance, and stability of motion. This paper starts with an analysis of different types of sensors that have been used in rotational wheel kinematics estimations and controls. The main attention is given to sensor signal limitations related to the accuracy of measurement and response time that are important for agile-to-real-time tire dynamics estimation.
A detailed analysis of the wheel rotational velocity estimation process is presented for a conventional Hall Effect digital sensor. Through an analytical modelling, it is shown that this sensor can limit its accuracy due to an increased time for signal information assembly caused by the number of impulses and transient (unsteady) rotational motion in unstable road conditions.
A new concept of a rotational kinematics sensor is proposed and modeled as a multi-domain mechatronic system that includes new mechanical elements as well as electrical and magnetic components. The sensor concept provides a smooth continuous signal through the full rotational angle of the wheel and precise information about the rotational velocity and its changes in different unstable road conditions. Computational examples of both sensors (digital and proposed) are demonstrated with the use of a quarter-car model moving over a random road profile in stochastic gripping and rolling resistance conditions. A comparison of the two sensors’ accuracy to estimate the rotational velocity of the wheel is done with regard to an “ideal” sensor with a unity transfer function.
Analysis and Passive Control of a Four-Bar Linkage for the Rehabilitation of Upper-Limb Motion
Authors: Xydas Evagoras G. , Louca Loucas S. , Mueller Andreas 
Published: January 2016

In the last two decades robotic rehabilitation research provided significant insight regarding the human-robot interaction, helped understand the process by which the impaired nervous system is retrained to better control movements, and led to the development of a number of mathematical and neurophysiological models that describe both the human motion and the robot control. The human-machine interaction in this research is typically achieved through robotic devices that are based on open kinematic chains. These devices have multiple degrees of freedom (DOF), sophisticated computer control, actuation and sensing. The flexibility of such approach enables the easy implementation of the various models and methods that have to be applied in order to maximize the potential of robotic rehabilitation.
On the other hand, mechanisms with fewer DOF’s that are based on closed kinematic chains can generate specific, yet adequate trajectories for the purposes of robotic rehabilitation. An example of such mechanisms is four-bar linkages that have only 1-DOF but yet can generate paths with complex kinematic characteristics. Design and analysis of four-bar linkages is used to achieve a variety of kinematics in terms of trajectory, velocity and acceleration profiles. The simplicity of these mechanisms is appealing and they can be used in rehabilitation due to their ability to replicate the motion of various human joints and limbs. The focus of the current work is to study the use of a four-bar linkage for generating the natural motion of upper-limb reaching tasks with the intention of using this mechanism for rehabilitation. This natural hand motion is described by a straight-line trajectory with a smooth bellshaped velocity profile, which in turn is generated by the well-established Minimum Jerk Model (MJM). The goal is to design passive control elements in a four-bar linkage that generate the required torque for producing the MJM motion. The passive elements are two linear translational springs that act on the driving link of a straight line generating mechanism. A design optimization is used to minimize the difference between the desired and actual input spring torque while remaining within the predefined design space. The final arrangement is simulated in a Multibody Dynamics software that applies feed-forward dynamics to generate the mechanism’s free response to the torque generated by the designed linear springs.
The results of this work suggest that systematic design of a four-bar linkage can lead to simple mechanisms that can replicate the natural motion of reaching tasks. Relatively inexpensive linear springs can be employed in the design of passive-active controlled therapeutic mechanisms. Further investigation that combines analysis of both active and passive control/actuation elements must be performed for finalizing the control design. Simulations and analysis that incorporate various impaired hand responses must be also performed in order to finalize the design.
The Human Disease-Associated Aβ Amyloid Core Sequence Forms Functional Amyloids in a Fungal Adhesin
Authors: Rameau Rachele D. , Jackson Desmond N. , Beaussart Audrey , Dufrêne Yves F. , Lipke Peter N. 
Published: January 2016

ABSTRACT

There is increasing evidence that many amyloids in living cells have physiological functions. On the surfaces of fungal cells, amyloid core sequences in adhesins can aggregate into 100- to 1,000-nm-wide patches to form high-avidity adhesion nanodomains on the cell surface. The nanodomains form through interactions that have amyloid-like properties: binding of amyloid dyes, perturbation by antiamyloid agents, and interaction with homologous sequences. To test whether these functional interactions are mediated by typical amyloid interactions, we substituted an amyloid core sequence, LVFFA, from human Aβ protein for the native sequence IVIVA in the 1,419-residue
Candida albicans
adhesin Als5p. The chimeric protein formed cell surface nanodomains and mediated cellular aggregation. The native sequence and chimeric adhesins responded similarly to the amyloid dye thioflavin T and to amyloid perturbants. However, unlike the native protein, the nanodomains formed by the chimeric protein were not force activated and formed less-robust aggregates under flow. These results showed the similarity of amyloid interactions in the amyloid core sequences of native Als5p and Aβ, but they also highlighted emergent properties of the native sequence. Also, a peptide composed of the Aβ amyloid sequence flanked by amino acids from the adhesin formed two-dimensional sheets with sizes similar to the cell surface patches of the adhesins. These results inform an initial model for the structure of fungal cell surface amyloid nanodomains.

IMPORTANCE
Protein amyloid aggregates are markers of neurodegenerative diseases such as Alzheimer’s and Parkinsonism. Nevertheless, there are also functional amyloids, including biofilm-associated amyloids in bacteria and fungi. In fungi, glycoprotein adhesins aggregate into cell surface patches through amyloid-like interactions, and the adhesin clustering strengthens cell-cell binding. These fungal surface amyloid nanodomains mediate biofilm persistence under flow, and they also moderate host inflammatory responses in fungal infections. To determine whether the amyloid-like properties of fungal surface nanodomains are sequence specific, we ask whether a disease-associated amyloid core sequence has properties equivalent to those of the native sequence in a fungal adhesin. A chimeric adhesin with an amyloid sequence from the Alzheimer’s disease protein Aβ instead of its native sequence effectively clustered the adhesins on the cell surface, but it showed a different response to hydrodynamic shear. These results begin an analysis of the sequence dependence for newly discovered activities for fungal surface amyloid nanodomains.