bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of star-forming dwarf galaxies at 0.1 ≲z ≲ 0.9 in VUDS: probing the low-mass end of the mass-metallicity relation
Authors: Calabrò A. , Amorín R. , Fontana A. , Pérez-Montero E. , Lemaux B. C. , Ribeiro B. , Bardelli S. , Castellano M. , Contini T. , De Barros S. , Garilli B. , Grazian A. , Guaita L. , Hathi N. P. , Koekemoer A. M. , Le Fèvre O. , Maccagni D. , Pentericci L. , Schaerer D. , Talia M. , Tasca L. A. M. , Zucca E. 
Published: February 2017

Context. The study of statistically significant samples of star-forming dwarf galaxies (SFDGs) at different cosmic epochs is essential for the detailed understanding of galaxy assembly and chemical evolution. However, the main properties of this large population of galaxies at intermediate redshift are still poorly known.
Aims. We present the discovery and spectrophotometric characterization of a large sample of 164 faint (iAB~ 23–25 mag) SFDGs at redshift 0.13 ≤ z ≤ 0.88 selected by the presence of bright optical emission lines in the VIMOS Ultra Deep Survey (VUDS). We investigate their integrated physical properties and ionization conditions, which are used to discuss the low-mass end of the mass-metallicity relation (MZR) and other key scaling relations.
Methods. We use optical VUDS spectra in the COSMOS, VVDS-02h, and ECDF-S fields, as well as deep multi-wavelength photometry that includes HST-ACS F814W imaging, to derive stellar masses, extinction-corrected star-formation rates (SFR), and gas-phase metallicities of SFDGs. For the latter, we use the direct method and a Te-consistent approach based on the comparison of a set of observed emission lines ratios with the predictions of detailed photoionization models.
Results. The VUDS SFDGs are compact (median re~ 1.2 kpc), low-mass (M∗~ 107–109M⊙) galaxies with a wide range of star-formation rates (SFR(Hα) ~ 10-3–101M⊙/yr) and morphologies. Overall, they show a broad range of subsolar metallicities (12 +log (O/H) =7.26–8.7; 0.04 ≲Z/Z⊙≲ 1). Nearly half of the sample are extreme emission-line galaxies (EELGs) characterized by high equivalent widths and emission line ratios indicative of higher excitation and ionization conditions. The MZR of SFDGs shows a flatter slope compared to previous studies of galaxies in the same mass range and redshift. We find the scatter of the MZR is partly explained in the low mass range by varying specific SFRs and gas fractions amongst the galaxies in our sample. In agreement with recent studies, we find the subclass of EELGs to be systematically offset to lower metallicity compared to SFDGs at a given stellar mass and SFR, suggesting a younger starburst phase. Compared with simple chemical evolution models we find that most SFDGs do not follow the predictions of a “closed-box” model, but those from a gas-regulating model in which gas flows are considered. While strong stellar feedback may produce large-scale outflows favoring the cessation of vigorous star formation and promoting the removal of metals, younger and more metal-poor dwarfs may have recently accreted large amounts of fresh, very metal-poor gas, that is used to fuel current star formation.
Spectral and rotational properties of near-Earth asteroid (162173) Ryugu, target of the Hayabusa2 sample return mission
Authors: Perna D. , Barucci M. A. , Ishiguro M. , Alvarez-Candal A. , Kuroda D. , Yoshikawa M. , Kim M.-J. , Fornasier S. , Hasegawa S. , Roh D.-G. , Müller T. G. , Kim Y. 
Published: February 2017

Context.The JAXA Hayabusa2 mission will perform the first ever sample return from a primitive asteroid. The target near-Earth asteroid (162173) Ryugu will be reached in mid-2018 and its samples will be returned to the Earth by the end of 2020.Aims.We want to improve the current knowledge of the compositional and rotational properties of Ryugu, which are still presenting some uncertainties that might affect the mission operations and scientific return.Methods.We acquired high-quality photometric time-series data with the FORS2 instrument at the Very Large Telescope of the European Southern Observatory (ESO-VLT, Chile). We also acquired four FORS2 visible spectra and three X-shooter spectra in the 0.35−2.15μm range, at different rotational phases.Results.We obtained the currently highest-quality visual light-curve of Ryugu. A best solution of ~7.63 h is found for the rotational period, while a short-period solution (i.e.,P≈ 3.8 h) is ruled out by the clearly non-symmetric light-curve. The obtained spectra are generally similar and featureless, but present a drop-off of the reflectance at <0.45μm, suggesting the presence of aqueously altered minerals on Ryugu. The best meteorite analogs for Ryugu are represented by thermally altered CM carbonaceous chondrites.Conclusions.Our new photometric data help to refine the target reference model used by the Hayabusa2 team for the mission preparation and implementation, improving our knowledge of Ryugu’s spin properties. Our new spectra constrain the compositional and geological context of the Ryugu’s surface in order to prepare the planning of mission observations and support the working group for the selection of possible landing and sampling sites.
Weight in the First Year of Life: Associations with Maternal Prepregnancy Body Mass Index and Gestational Weight Gain—Findings from a Longitudinal Pregnancy Cohort
Authors: McPhie Skye , Skouteris Helen , Mattick Richard , Wilson Judy , Honan Ingrid , Allsop Steve , Burns Lucy , Elliott Elizabeth , Teague Samantha , Olsson Craig , Hutchinson Delyse 
Published: February 2017

Objective To investigate the obesogenic influence of maternal prepregnancy body mass index (BMI) and gestational weight gain (GWG) on infant weight at birth and 12 months postpartum in an Australian general population sample.
Methods Data on 1,305 pregnant women were collected on prepregnancy BMI and GWG through maternal interview, on infant weight at birth through hospital records, and on infant weight 12 months postbirth through direct measurement. Relationships between prepregnancy, gestational weight exposures, and infant weight outcomes were assessed with and without adjustment for potential confounding.
Results We observed a 14 to 24 g increase in infant birth weight for every 1 kg increase in maternal weight (infant birth weight: β(BMI) = 0.014, p < 0.000; β(GWG) = 0.012, p < 0.000; and 12 months: β(BMI) = 0.018, p < 0.000; β(GWG) = 0.024, p < 0.000). Effects remained after adjustment for potential confounders (infant birth weight: β(BMI) = 0.014, p < 0.000; β(GWG) = 0.012, p < 0.001; and 12 months: β(BMI)= 0.017, p ≤ 0.033; β(GWG) = 0.023, p = 0.001). However, the effects observed were small, and there was no evidence that GWG mediated relationships between preconception BMI and infant weight.
Conclusion In a general population sample, there is a significant but not substantial observed relationship between maternal prepregnancy BMI and GWG and infant weight outcomes, suggesting a minor role for these factors at a population level.
Dringlichkeit von hausärztlichen Notfallbesuchen in Altenheimen
Authors: Bleckwenn Markus , Ahrens Sabrina , Schnakenberg Rieke , Weckbecker Klaus 
Published: February 2017

ZusammenfassungBisher gibt es keine einheitlichen Kriterien oder Standards für die Dringlichkeitseinstufung von Hausbesuchen. Aufgrund des demographischen Wandels werden insbesondere dringende Hausbesuche in Altenheimen zunehmen. In der URGENT-Studie stuften Ärzte und Pflegekräfte die Dringlichkeit von Notfallhausbesuchen in Seniorenpflegeheimen vor und nach dem Hausbesuch ein. Damit sollte erfasst werden, wie viele Notfallhausbesuche im Nachhinein als weniger dringend eingestuft werden und wie häufig Ärzte und Pflegende in ihrer Einschätzung übereinstimmen.Im Rahmen einer prospektiven Beobachtungsstudie wurden Hausbesuche ausgewertet, die von den Hausärzten bei Anforderung als dringend eingestuft wurden. Nach der Durchführung der Heimbesuche stuften sowohl der Hausarzt als auch die verantwortliche Pflegefachkraft die Dringlichkeit des Heimbesuches von 0 (überhaupt nicht dringend) bis10 (sehr dringend) ein. Zusätzlich wurden die Uhrzeiten der Heimbesuchsanfragen bzw. Durchführung, sowie die Gründe für die Hausbesuche dokumentiert.Es wurden 75 dringende Heimbesuche ausgewertet. Die Patienten waren im Durchschnitt 82 Jahre alt (65% weiblich). Die Hausbesuche wurden im Durchschnitt 2,5 Stunden nach ihrer Anforderung durchgeführt. Im Nachhinein stuften die Hausärzte die Notfallhausbesuche im Durchschnitt weniger dringend (5,7±2,7) als die Pflegekräfte (7,2±2,2) ein. 20% der Notfallhausbesuche (15 Fälle) stuften sowohl Ärzte als auch Pflegekräfte übereinstimmend als weniger dringend (0–5) ein.Unsere Daten zeigen, dass bei der bisher nicht standardisierten Einschätzung der Dringlichkeit ein erheblicher Anteil der Hausbesuche falsch kategorisiert wird. In weiteren Studien ist zu prüfen, ob ein einheitlicher Score zur Dringlichkeitseinschätzung den Anteil dieser Fehleinsätze verringern und so die Effizienz der Notfallversorgung von Altenpflegeheimen verbessern könnte.
Antibiotikaresistenz: In welchen Handlungsfeldern muss mehr getan werden?
Authors: Sauskojus Hendrik , Wagner-Ahlfs Christian , Razum Oliver 
Published: February 2017

ZusammenfassungAntibiotika werden seit Jahrzehnten erfolgreich zur Behandlung von Infektionskrankheiten eingesetzt. Die Entwicklung von Resistenzen ist hierbei ein natürlicher Vorgang. Mit dem weltweit kontinuierlich ansteigenden Antibiotika-Verbrauch wird dieser Vorgang jedoch stark beschleunigt. Schon jetzt sind Infektionskrankheiten wie die Tuberkulose oder Gonorrhoe oft nur noch schwer behandelbar. Auch nosokomiale Infektionen mit multiresistenten Keimen stellen inzwischen ein großes Problem für die Gesundheitsversorgung dar. Es wurden bereits mehrere Aktionspläne und Gegenmaßnahmen entwickelt, welche indes nur unzureichend umgesetzt werden und nicht alle auftretenden Probleme adressieren. Dies ist in verschiedenen Handlungsfeldern jedoch dringend erforderlich, sollen Antibiotika auch in Zukunft für eine erfolgreiche Infektionsbehandlung zur Verfügung stehen.
K isotopes as a tracer of seafloor hydrothermal alteration
Authors: Parendo Christopher A. , Jacobsen Stein B. , Wang Kun 
Published: February 2017

Significance
Elemental exchange between seawater and oceanic crust is important both in modulating the ionic composition of seawater over geologic time and in controlling the elemental and isotopic makeup of various solid-earth reservoirs. This study documents large and systematic variations in the K-isotope composition of oceanic crust that has been affected by seafloor hydrothermal alteration. These variations put constraints on the isotopic character of a fundamental flux of the marine K cycle: the hydrothermal flux. We also propose that these variations ought to be exploited in the future as an effective way of tracking oceanic crust as it is subducted into the mantle and sampled by various forms of volcanism.
Pure circular polarization electroluminescence at room temperature with spin-polarized light-emitting diodes
Authors: Nishizawa Nozomi , Nishibayashi Kazuhiro , Munekata Hiro 
Published: February 2017

Significance
Most of the experiments on the spin manipulation in semiconductors, the principal materials in modern electronic and photonic devices, were carried out at cryogenic temperatures and high magnetic fields because thermal energy tends to randomize spin information in the semiconductor that is nonmagnetic. Here, we report very surprising experimental results of pure circular polarization electroluminescence at room temperature with no external magnetic fields. The results are obtained by electrically injecting moderately high density of spins into semiconductor double heterostructures, the structures that were invented in connection with semiconductor lasers one-half century ago. The results suggest the appearance of some spin-dependent nonlinear processes that lead to recovering and even enhancing the injected, initial spin information in semiconductors.
SGK3 sustains ERα signaling and drives acquired aromatase inhibitor resistance through maintaining endoplasmic reticulum homeostasis
Authors: Wang Yuanzhong , Zhou Dujin , Phung Sheryl , Warden Charles , Rashid Rumana , Chan Nymph , Chen Shiuan 
Published: February 2017

SignificanceAcquired aromatase inhibitor (AI) resistance is a major clinical issue in the treatment of estrogen receptor alpha (ERα)-positive breast cancer. Most AI-resistant breast tumors still express ERα and rely on its signaling for growth. The current study shows that serum- and glucocorticoid-inducible kinase 3 (SGK3), a kinase transcriptionally regulated by ERα in breast cancer, sustains ERα signaling and drives the acquired AI resistance by protecting against endoplasmic reticulum (EnR) stress-induced ERα downregulation and cell death through preserving sarcoplasmic/EnR calcium ATPase 2b (SERCA2b) function. Our study reveals regulation of ERα expression mediated by the EnR stress response and highlights SGK3 inhibition as a potential effective treatment of acquired AI-resistant breast cancer.
Reelin transiently promotes N-cadherin–dependent neuronal adhesion during mouse cortical development
Authors: Matsunaga Yuki , Noda Mariko , Murakawa Hideki , Hayashi Kanehiro , Nagasaka Arata , Inoue Seika , Miyata Takaki , Miura Takashi , Kubo Ken-ichiro , Nakajima Kazunori 
Published: February 2017

Significance
It has long been thought that Reelin is a stop signal for migrating neocortical neurons, because the neurons stop just beneath Reelin-rich regions. Our recent studies revealed that ectopically expressed Reelin can also cause neuronal aggregation with clear demarcation in vivo, suggesting that Reelin is not simply a stop signal. However, it remains unclear whether Reelin directly promotes adhesion among neurons or only causes them to be repelled by the surrounding cellular environment, facilitating their aggregation. We show here that Reelin directly promotes N-cadherin–dependent neuronal adhesion, causing neuronal aggregation. This Reelin-dependent neuronal adhesion occurs only transiently, and is not sustained. This dynamic change of N-cadherin–mediated cellular adhesiveness is important for establishment of the appropriate layering of neocortical neurons.
Distributed representation of context by intrinsic subnetworks in prefrontal cortex
Authors: Waskom Michael L. , Wagner Anthony D. 
Published: February 2017

Significance
Information is represented in the brain by distributed patterns of cortical activity. In sensory cortex, these patterns are expressed across circuits with an intrinsic functional architecture that is organized along relevant stimulus dimensions. However, it is unknown whether similar organizational principles underlie distributed representations of more abstract information, such as rules or goals. We analyzed correlations in spontaneous activity to identify fine-scaled subnetworks in human prefrontal cortex. These subnetworks were differentially engaged when subjects followed rules in a complex decision-making task. Our results show how the abstract representations that support goal-directed cognition are constrained by an intrinsic functional architecture and prompt new models of information representation in association cortex.
Role of vascular normalization in benefit from metronomic chemotherapy
Authors: Mpekris Fotios , Baish James W. , Stylianopoulos Triantafyllos , Jain Rakesh K. 
Published: February 2017

Significance
Metronomic dosing has been proposed as an alternative to maximum tolerated doses of chemotherapy. Even though this strategy has shown promise in improving therapeutic outcomes in some cases, the underlying mechanisms of action are not fully understood. In this study, using mathematical modeling, we show that metronomic chemotherapy could be beneficial by normalizing tumor blood vessel function and improving tumor perfusion. Improved perfusion enhances the delivery of drugs to solid tumors and alleviates hypoxia. These effects also result in an improved immune response, contributing to increased killing of cancer cells, including more resistant cancer stem-like cells.
Tryptophan introduction can change β-glucan binding ability of the carbohydrate-binding module of endo-1,3-β-glucanase
Authors: Miki Ayako , Inaba Satomi , Maruno Takahiro , Kobayashi Yuji , Oda Masayuki 
Published: February 2017

Abstract
Endo-1,3-β-glucanase from Cellulosimicrobium cellulans DK-1 has a carbohydrate-binding module (CBM-DK) at the C-terminal side of a catalytic domain. Out of the imperfect tandem α-, β-, and γ-repeats in CBM-DK, the α-repeat primarily contributes to β-glucan binding. This unique feature is derived from Trp273 in α-repeat, whose corresponding residues in β- and γ-repeats are Asp314 and Gly358, respectively. In this study, we generated Trp-switched mutants, W273A/D314W, D270A/W273A/D314W, W273A/G358W, and D270A/W273A/G358W, and analyzed their binding abilities toward laminarioligosaccharides and laminarin. While the binding affinities of D270A/W273A and W273A mutants were either lost or much lower than that of the wild-type, those of Trp-switched mutants recovered, indicating that a Trp introduction in β- or γ-repeat can substitute the α-repeat by primarily contributing to β-glucan binding. Thus, we have successfully engineered a CBM-DK that binds to laminarin by a mechanism different from that of the wild-type, but with similar affinity.
Democracy and Government: A Critical Edition of Jeannette Rankin’s 1917 Address at Carnegie Hall
Authors: Lewis Tiffany 
Published: February 2017

Abstract
In 1917, Jeannette Rankin became the United States’ first female member of Congress. This is a critical edition of the speech Rankin gave before 3,000 people in New York City on her way to be sworn in to office. Her speech promoted her home state of Montana, woman suffrage, and direct democracy.
The Enthymizing of Lysias
Authors: Fredal James 
Published: February 2017

ABSTRACTLysias is best known for his portrayal of character (ethopoiia), his believable narratives, his plain or “Attic” style, and for the role he plays as inferior foil to Socrates in Plato’s Phaedrus. But he was also an important figure in developing, refining, and employing types of argument, including the rhetorical technique that would later be called the enthymeme. In On the Death of Eratosthenes, Lysias not only uses enthymemes, he highlights their use, selects a term (enthymizing), and demonstrates how “enthymizing” could be central to rhetorical artistry, to narrative development, to legal reasoning, and to political activism. Examining Lysias 1 not only deepens our understanding of Lysias’ rhetorical abilities, but it suggests that the orators had an important role to play in the development of rhetorical theory.
“Government Is an Instrument in Their Hands”: Jeanette Rankin on Progressive Technologies of Democracy
Authors: Koenig Richards Cindy , McKean Paul 
Published: February 2017

ABSTRACT
Jeannette Rankin’s 1917 address at Carnegie Hall is replete with metaphors of political machinery, systems, and technologies. We argue that the metaphor of political machinery is central to Rankin’s definition and enactment of democratic power because it creates a cohesive vision of systemic change that combines equal suffrage with other progressive reforms. While scholars have noted Rankin’s appeals to domestic ideology, the political-machinery metaphor cluster provides a broader justification for equal suffrage as a necessary part of a democratic system. Further, Rankin’s deconstruction of the complexities of political machinery works to enact Rankin’s political leadership as the first woman to serve in the United States Congress.
Mapping the Soundscape Off the Southeastern USA by Using Passive Acoustic Glider Technology
Authors: Wall Carrie C. , Mann David A. , Lembke Chad , Taylor Chris , He Ruoying , Kellison Todd 
Published: February 2017

Abstract
The purpose of this study was to explore the soundscape of shelf-edge Atlantic waters of the southeastern USA (SEUS) during winter by using passive acoustic and autonomous glider technologies, with a focus on the distribution of groupers. An autonomous glider was deployed off the SEUS coast near Cape Canaveral, Florida, on March 3, 2014, and transited to Cape Fear, North Carolina, where it was retrieved on April 1, 2014. Using satellite and hydrodynamic model data for guidance, the glider piloted in and out of the Gulf Stream, taking advantage of the high currents to reach the targeted sampling area. Ambient noise was recorded by an integrated passive acoustic recorder during the 29-d mission, in which the glider traveled 895 km and reached waters 267 m deep. A variety of sounds was identified in the acoustic recordings, including sounds generated by Red Grouper Epinephelus morio and toadfishes Opsanus sp.; two sounds previously documented in the Gulf of Mexico that were suspected to be produced by fish; whistles and echolocation from marine mammals; and extensive vessel noise. Numerous sounds from previously undocumented sources were also recorded. The Red Grouper was the only serranid that was consistently identified from the sound data, with detections occurring within and outside of South Atlantic Fishery Management Council marine protected areas. This research demonstrates the potential utility of a glider-based passive acoustic approach as a component of a program to map fish, marine mammal, and vessel distributions over large scales.
VEXOR: an integrative environment for prioritization of functional variants in fine-mapping analysis
Authors: Lemaçon Audrey , Joly Beauparlant Charles , Soucy Penny , Allen Jamie , Easton Douglas , Kraft Peter , Simard Jacques , Droit Arnaud 
Published: February 2017

Abstract

Motivation
The identification of the functional variants responsible for observed genome-wide association studies (GWAS) signals is one of the most challenging tasks of the post-GWAS research era. Several tools have been developed to annotate genetic variants by their genomic location and potential functional implications. Each of these tools has its own requirements and internal logic, which forces the user to become acquainted with each interface.

Results
From an awareness of the amount of work needed to analyze a single locus, we have built a flexible, versatile and easy-to-use web interface designed to help in prioritizing variants and predicting their potential functional implications. This interface acts as a single-point of entry linking association results with reference tools and relevant experiments.

Availability and Implementation
VEXOR is an integrative web application implemented through the Shiny framework and available at: http://romix.genome.ulaval.ca/vexor.

Supplementary information
Supplementary data are available at Bioinformatics online.