bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling the chemistry of star-forming filaments – I. H2 and CO chemistry
Authors: Seifried D. , Walch S. 
Published: March 2016

Abstract
We present simulations of star-forming filaments incorporating on of the largest chemical network used to date on-the-fly in a 3D-magnetohydrodynamic (MHD) simulation. The network contains 37 chemical species and about 300 selected reaction rates. For this, we use the newly developed package krome (Grassi et al.). We combine the krome package with an algorithm which allows us to calculate the column density and attenuation of the interstellar radiation field necessary to properly model heating and ionization rates. Our results demonstrate the feasibility of using such a complex chemical network in 3D-MHD simulations on modern supercomputers. We perform simulations with different strengths of the interstellar radiation field and the cosmic ray ionization rate. We find that, towards the centre of the filaments, there is gradual conversion of hydrogen from H to H2 as well as of C+ over C to CO. Moreover, we find a decrease of the dust temperature towards the centre of the filaments in agreement with recent HERSCHEL observations.
Suzaku Wide-band All-sky Monitor measurements of duration distributions of gamma-ray bursts
Authors: Ohmori Norisuke , Yamaoka Kazutaka , Ohno Masanori , Sugita Satoshi , Kinoshita Ryuuji , Nishioka Yusuke , Hurley Kevin , Hanabata Yoshitaka , Tashiro Makoto S. , Enomoto Junichi , Fujinuma Takeshi , Fukazawa Yasushi , Iwakiri Wataru , Kawano Takafumi , Kokubun Motohide , Makishima Kazuo , Matsuoka Shunsuke , Nagayoshi Tsutomu , Nakagawa Yujin E. , Nakaya Souhei , Nakazawa Kazuhiro , Takahashi Tadayuki , Takeda Sawako , Terada Yukikatsu , Urata Yuji , Yabe Seiya , Yasuda Tetsuya , Yamauchi Makoto 
Published: March 2016

Abstract
We report on the T90 and T50 duration distributions and their relations with spectral hardness using 1464 gamma-ray bursts (GRBs), which were observed by the Suzaku Wide-band All-sky Monitor (WAM) from 2005 August 4 to 2010 December 29. The duration distribution is clearly bimodal in three energy ranges (50–120, 120–250, and 250–550 keV), but is unclear in the 550–5000 keV range, probably because of the limited sample size. The WAM durations decrease with energy according to a power-law index of −0.058(−0.034, +0.033). The hardness–duration relation reveals the presence of short–hard and long–soft GRBs. The short:long event ratio tends to be higher with increasing energy. We compared the WAM distribution with ones measured by eight other GRB instruments. The WAM T90 distribution is very similar to those of INTEGRAL/SPI-ACS and Granat/PHEBUS, and least likely to match the Swift/BAT distribution. The WAM short:long event ratio (0.25:0.75) is much different from Swift/BAT (0.08:0.92), but is almost the same as CGRO/BATSE (0.25:0.75). To explain this difference for BAT, we examined three effects: BAT trigger types, energy dependence of the duration, and detection sensitivity differences between BAT and WAM. As a result, we found that the ratio difference could be explained mainly by energy dependence including soft extended emissions for short GRBs and much better sensitivity for BAT which can detect weak/long GRBs. The reason for the same short:long event ratio for BATSE and WAM was confirmed by calculation using the trigger efficiency curve.
Application of the Ghosh & Lamb relation to the spin-up/down behavior in the X-ray binary pulsar 4U 1626−67
Authors: Takagi Toshihiro , Mihara Tatehiro , Sugizaki Mutsumi , Makishima Kazuo , Morii Mikio 
Published: March 2016

Abstract
We analyzed continuous Monitor of All-sky X-ray Image/Gas Slit Camera (MAXI/GSC) data of the X-ray binary pulsar 4U 1626−67 from 2009 October to 2013 September, and determined the pulse period and the pulse-period derivative for every 60-d interval by the epoch folding method. The obtained periods are consistent with those provided by the Fermi/Gamma-ray Burst Monitor pulsar project. In all the 60-d intervals, the pulsar was observed to spin up, with the spin-up rate positively correlated with the 2–20 keV flux. We applied the accretion torque model proposed by Ghosh and Lamb (1979, ApJ, 234, 296) to the MAXI/GSC data, as well as the past data including both spin-up and spin-down phases. The “Ghosh & Lamb” relation was confirmed to successfully explain the observed relation between the spin-up/down rate and the flux. By comparing the model-predicted luminosity with the observed flux, the source distance was constrained as 5–13 kpc, which is consistent with that found by Chakrabarty (1998, ApJ, 492, 342). Conversely, if the source distance is assumed, the data can constrain the mass and radius of the neutron star, because the Ghosh & Lamb model depends on these parameters. We attempted this idea, and found that an assumed distance of, e.g., 10 kpc gives a mass in the range of 1.81–1.90 solar mass, and a radius of 11.4–11.5 km, although these results are still subject to considerable systematic uncertainties, other than distance.
Clinical Practice Recommendations for the Management and Prevention of Cisplatin-Induced Hearing Loss Using Pharmacogenetic Markers
Authors: Lee Jong W. , Pussegoda Kusala , Rassekh Shahrad R. , Monzon Jose G. , Liu Geoffrey , Hwang Soomi , Bhavsar Amit P. , Pritchard Sheila , Ross Colin J. , Amstutz Ursula , Carleton Bruce C. ,   the CPNDS Clinical Recommendations Group
Published: March 2016

Abstract:
Currently no pharmacogenomics-based criteria exist to guide clinicians in identifying individuals who are at risk of hearing loss from cisplatin-based chemotherapy. This review summarizes findings from pharmacogenomic studies that report genetic polymorphisms associated with cisplatin-induced hearing loss and aims to (1) provide up-to-date information on new developments in the field, (2) provide recommendations for the use of pharmacogenetic testing in the prevention, assessment, and management of cisplatin-induced hearing loss in children and adults, and (3) identify knowledge gaps to direct and prioritize future research. These practice recommendations for pharmacogenetic testing in the context of cisplatin-induced hearing loss reflect a review and evaluation of recent literature, and are designed to assist clinicians in providing optimal clinical care for patients receiving cisplatin-based chemotherapy.
Influence of Partial External Biliary Diversion on the Lipid Profile in Children With Progressive Familial Intrahepatic Cholestasis
Authors: Jankowska Irena , Czubkowski Piotr , Wierzbicka Aldona , Pawłowska Joanna , Kaliciński Piotr , Socha Piotr 
Published: March 2016

ABSTRACTObjectives:The concentration of bile acids is highly increased in progressive familial intrahepatic cholestasis (PFIC). Bile acids are the end products of cholesterol metabolism, and aid in the absorption of fat‐soluble vitamins and dietary fat. The aim of our study was to investigate lipid metabolism in patients with PFIC with focus on the effect of partial external biliary diversion (PEBD).Methods:In 26 patients with PFIC, who underwent PEBD surgery at the median age of 2.2 years (range: 0.4–16.6), we analyzed the concentrations of lipids and apolipoproteins both before and 6 months after PEBD. Patients were split into 2 groups according to the outcome of surgery (either “good” or “poor”), and were analyzed separately. A “good” result following surgery was defined as complete relief from pruritus, and normalization of total bilirubin (<1.0 mg/dL) and bile acid concentration in serum (<12 μmol/L).Results:We found abnormal lipid concentrations at baseline in all 26 patients: cholesterol was increased (>190 mg/dL) in 13 patients, phospholipids were increased (>250 mg/dL) in 5 patients, and triglyceride concentration was increased (>150 mg/dL) in 13 patients. After PEBD, the concentrations of plasma cholesterol, triglycerides, and phospholipids decreased significantly, whereas, ApoA‐I and high‐density lipoprotein cholesterol concentrations increased and the concentrations of apolipoprotein B, low‐density lipoprotein cholesterol, and very low‐density lipoprotein cholesterol significantly decreased. PEBD had neither an effect on ApoE concentration nor on lecithin‐cholesterol acyl transferase activity. In the group with a “poor” outcome report following PEBD, total serum cholesterol concentration decreased significantly, and no effect on the concentrations of triglycerides and phospholipids were observed.Conclusions:Patients with PFIC present with a high risk of lipid disturbances. PEBD has a beneficial effect on lipid profile in the majority of cases.
Complementary and Alternative Medicine Use in Children With Inflammatory Bowel Diseases
Authors: Serpico Mark R. , Boyle Brendan M. , Kemper Kathi J. , Kim Sandra C. 
Published: March 2016

ABSTRACTObjectives:The prevalence of inflammatory bowel diseases (IBD) and use of complementary and alternative medicine (CAM) are both common and increasing. The definition of CAM therapy among both practitioners and patients is variable. The aim of our study was to update our understanding of how pediatric IBD patients use, perceive, and define CAM therapies.Methods:We surveyed families of patients with IBD followed in the Gastroenterology Division at Nationwide Children's Hospital in summer 2014 during a routine clinic visit. The survey included questions about the following demographic and disease information; use and side effects associated with prior conventional therapies (CT); and attitudes toward, and use of CAM.Results:The questionnaire was completed by 104 of 118 patients approached (14 ± 3 years; 43% women). Patients had previously used an average of 3 CT. CAM therapy was used by 84% of patients surveyed, although only 24% of patients/families considered themselves to be using CAM. Common CAM therapies included vitamins/supplements, stress management techniques, and/or dietary changes. Factors associated with using specific CAM therapies included self‐reported prior CT‐related side effects (P < 0.01) and moderate/severe disease activity (P < 0.01). Most families (77%) desired to learn more about CAM.Conclusions:Patients seen in a tertiary care center for pediatric IBD frequently integrated CAM therapies into their treatment regimen. Patients with prior side effects from CT or more severe disease were more likely to use CAM. Given the high prevalence of CAM use, pediatric gastrointestinal physicians should be knowledgeable and open to discussions about CAM therapies with their patients.
Sonographic Diagnosis of Periorbital Dermoid Cyst
Authors: Whittle Carolina , Retamal Andres , Kramer Daniela , Silva Claudio 
Published: March 2016

Abstract
Periorbital dermoid cysts occur mainly in children. Sonography is useful for the noninvasive, nonionizing evaluation of soft tissue lesions in infants and children without requiring sedation or anesthesia. We report the sonographic appearance of 25 periorbital dermoid cysts and identified that all are avascular oval lesions located below the aponeurotic plane. Nonaggressive bone remodeling was present in 52% of the cases. These finding in pediatric periorbital lesions are highly suspicious of a periorbital dermoid cyst.
The Clinical Application of Preexpanded and Prefabricated Super-Thin Skin Perforator Flap for Reconstruction of Post-Burn Neck Contracture
Authors: Wang Chunmei , Zhang Junyi , Yang Sifen , Hyakusoku Hiko , Song Ping , Pu Lee L.Q. 
Published: March 2016

Objective
Based on our previous animal study, we applied the “bridging effect” to the neighboring axial flap through preexpansion and prefabrication of a skin perforator flap as a new method to reconstruct a large skin defect after release of severe neck burn scar contracture.

Methods
Twelve patients suffering from severe post-burn cervical contractures underwent reconstruction of large skin defects after surgical release of severe scar contractures with preexpanded and prefabricated super-thin skin perforator flaps supplied primarily by a number of perforators via the “bridging effect” from the branches of the adjacent arteries as 2-stage procedures. During the first-stage operation, 2 tissue expanders were placed accordingly, and this was followed by a subsequent second-stage procedure where an expanded super-thin skin perforator flap was transposed to reconstruct a large neck skin defect. Follow-up was between 6 months and 3 years in this series.

Results
All super-thin skin perforator flaps survived in this series with primary healing except one with a distal flap necrosis that was treated with a subsequent skin graft. All patients have had a good contour with improved range of motion in the neck.

Conclusions
The preexpansion and prefabrication of a super-thin skin perforator flap can possibly improve the anastomoses between neighboring subdermal vascular plexuses and extend the supplying area of these vessels to the flap. This method may provide a favorable super-thin skin flap that can be used for reconstruction of large neck defects after release of post-burn cervical scar contracture as demonstrated in this case series.
Evaluation Indicators of Aesthetic Effects on Hair Transplantation
Authors: Miao Yong , Liu Bing-cheng , Fan Zhe-xiang , Hu Zhi-qi 
Published: March 2016

Abstract
Hair transplantation involves the transplantation of hair, beard, eyebrows, eyelashes, and pubic hair. Based on our experience, the aesthetic result of hair transplantation mainly relies on 4 indicators, including selection of the donor site, direction and angle of grafted hairs, density, and survival rate of implanted hair follicles. We believe that good results can be achieved as long as attention is paid to the above 4 points.
Engineered kinesin motor proteins amenable to small molecule inhibition
Authors: Engelke Martin F. , Winding Michael , Yue Yang , Shastry Shankar , Teloni Federico , Reddy Sanjay , Blasius T. Lynne , Soppina Pushpanjali , Hancock William O. , Gelfand Vladimir I. , Verhey Kristen J. 
Published: March 2016

ABSTRACTThe human genome encodes 45 kinesins that drive cell division, cell motility, intracellular trafficking, and ciliary function. Determining the cellular function of each kinesin would be greatly facilitated by specific small molecule inhibitors, but screens have yielded inhibitors that are specific to only a small number of kinesins, likely due to the high conservation of the kinesin motor domain across the superfamily. Here we present a chemical-genetic approach to engineer kinesin motors that retain microtubule-dependent motility in the absence of inhibitor yet can be efficiently inhibited by small, cell-permeable molecules. Using kinesin-1 as a prototype, we tested two independent strategies to design inhibitable motors. First, we inserted the six amino acid tetracysteine tag into surface loops of the motor domain such that binding of biarsenic dyes allosterically inhibits processive motility. Second, we fused DmrB dimerization domains to the motor heads such that addition of B/B homodimerizer cross-links the two motor domains and inhibits motor stepping. We show, using cellular assays that the engineered kinesin-1 motors are able to transport artificial and natural kinesin-1 cargoes, but are efficiently inhibited by the addition of the relevant small molecule. Single-molecule imagingin vitrorevealed that inhibitor addition reduces the number of processively moving motors on the microtubule, with minor effects on motor run length and velocity. It is likely that these inhibition strategies can be successfully applied to other members of the kinesin superfamily due to the high conservation of the kinesin motor domain. The described engineered motors will be of great utility to dynamically and specifically study kinesin function in cells and animals.
So, who really is a “noted author” within the accounting literature? A reflection on Benson et al. (2015)
Authors: Deegan Craig 
Published: March 2016

Purpose
– The purpose of this paper is to explore the propensity of some researchers within the accounting research community (and elsewhere) to ignore potentially rich insights available from other paradigms, and the implications this has for the advancement of knowledge both from an educational and a social perspective.

Design/methodology/approach
– The analysis is based on a review of a paper published in the Australian Journal of Management by Benson et al. (2015) together with a synthesis of other work which cautions against dismissing conflicting “world views”.

Findings
– The analysis suggests that the propensity of some accounting researchers to dismiss, or ignore, research undertaken by researchers outside of their paradigm is still apparently “alive and well” within today’s accounting research community. The implications associated with ignoring or dismissing rich interdisciplinary insights are highlighted.

Research limitations/implications
– The implications of the research are that many rich insights are apparently being ignored by a segment of the accounting research community and this has implications for the advancement of knowledge, education and society. The limitations of this commentary are that the views are based on personal opinion which by its very nature is biased and based on the political views of the author.

Practical implications
– The practical implications are that in highlighting a propensity to ignore potentially valuable research from alternative paradigms the commentary encourages researchers to consider other world views, as well as the political foundations inherent in their own work. This can have positive implications for the advancement of knowledge, and of society.

Social implications
– By highlighting the propensity of some researchers to potentially dismiss entire areas of research as not being “notable” it is hoped that there will be a revision of this tendency and this will have possible implications for the advancement of knowledge.

Originality/value
– The commentary highlights how certain elements of the accounting research community continue to appear to have a propensity to forget/ignore that potentially useful insights are available from people who undertake research beyond the confines of their research paradigm.
Community disclosures in a developing country: insights from a neo-pluralist perspective
Authors: Soobaroyen Teerooven , Mahadeo Jyoti Devi 
Published: March 2016

Purpose
– The purpose of this paper is to analyse changes in community disclosures by listed companies in Mauritius.

Design/methodology/approach
– The authors carried out a quantitative and qualitative assessment of annual report disclosures over the period 2004-2010. In particular, the authors consider the influence of a corporate governance code and a government intervention to first persuade and subsequently mandate corporate social responsibility investment (known as a “CSR Levy”).

Findings
– From a predominantly limited and neutral form of communication, narratives of community involvement morph into assertive and rhetorical statements, emphasising commitment, permanency and an intimate connection to the community and a re-organisation of activities and priorities which seek to portray structure and order in the way companies deliver community interventions. Informed by Gray et al.’s (1995) neo-pluralist framework and documentary evidence pertaining to the country’s social, political and economic context, the authors relate the change in disclosures to the use of corporate impression management techniques with a view to maintain legitimacy and to counter the predominant public narrative on the insufficient extent of community involvement by local companies.

Research limitations/implications
– The authors find that community disclosures are not only legitimating mechanisms driven by international pressures but are also the result of local tensions and expectations.

Originality/value
– This study provides evidence on forms of “social” – as opposed to environmental – disclosures. Furthermore, it examines a unique setting where a government enacted a legally binding regime for greater corporate social involvement.
Motivations of manufacturing reshoring: an interpretative framework
Authors: Fratocchi Luciano , Ancarani Alessandro , Barbieri Paolo , Di Mauro Carmela , Nassimbeni Guido , Sartor Marco , Vignoli Matteo , Zanoni Andrea 
Published: March 2016

Purpose
– The purpose of this paper is to present a framework for the analysis of reshoring. The framework is then applied to analyze motivations for reshoring, as they emerge from extant literature and from new evidence collected.

Design/methodology/approach
– The authors start by formulating a literature-grounded definition of reshoring and reviewing some key theoretical approaches for international manufacturing location. In light of these theories, the authors then propose an interpretative framework for the analysis of reshoring motivations. Finally, the authors provide new evidence on this phenomenon, by presenting the findings of an extensive data collection of reshoring cases built on secondary data.

Findings
– The authors show that a vast array of single drivers of reshoring can be extracted from extant literature; however, the interpretative framework eventually highlights four main typologies of reshoring motivations, thus allowing for a more sound comprehension of why the phenomenon happens. The empirical investigation proves also useful in comparing the relative importance of these motivations, as it reveals that value-driven and country-specific motivations prevail over efficiency-driven and firm-specific ones, respectively.

Research limitations/implications
– The study is based on the analyses of secondary data extracted from newspapers and magazine sources. Some motivations (and especially those that configure a “correction of a previous erroneous decision”) could have been underestimated. In addition, certain industries (e.g. clothing and footwear), certain countries (USA and China), and certain firms (large companies and MNCs) could have more visibility to the media. Another possible limitation is due to the fact that the classification work inherently implied some discretion and individual judgment. The authors however spent considerable efforts in cross-validating the assessments through extensive discussion within the research team.

Originality/value
– This is the first paper that summarizes the motivations of the rising reshoring phenomenon and interprets them based on an original theory-derived classification framework.