bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tendencia de la cobertura vegetacional afectada por incendios en el Parque Nacional Torres del Paine
Authors: Rivera C. , Mattar C. , Durán-Alarcón C. 
Published: December 2017

<p>Torres del Paine National Park (PNTP) is characterized as a representative geographical area of the world’s ecosystems, containing high scenic beauty and wide variety of ecosystems. The aim of this work is to analyze the spatial and temporal trends of vegetation at PNTP using remote images from the Landsat platforms, the MOD13A3 product from the Moderate Resolution Imaging Spectroradiometer (MODIS), coverage maps surface Global Land cover Maps of ESA/CCI 2005 and 2010 and a land cover map of continental Chile of 2014. In addition, the products of Soil Moisture and Ocean Salinity (SMOS) and meteorological data from the Torres del Paine meteorological station were used to analyze the environmental conditions that presented the park while the fire occurred the years 2011-2012. To determine the magni­tude of the changes of vegetation affected by fire at PNTP a nonparametric trend analysis was use with the Normalized Difference Vegetation Index (NDVI) of MODIS from 2002 to 2016 and the Normalized Burn Ratio (NBR) for the fire occurred the year 2005 and the years 2011-2012. The results show that between both fires it is been affected more than 30.000 hectares of the national park, being the “Scrub” and “Forest” coverage the most affected due to the high level of severity and the low regeneration of the burn area (less than 56%). The soil moisture does not exceed 20% m<sup>3</sup>m<sup>-3</sup> before the fire and the rainfall does not exceed 101 mm during the days of fire, which is related to an increase in the probability of propa­gation of the fire. In this work is possible to realize that remote sensing can be used in the fire management to regard the national parks with the objective of preserve and conserve the flora, fauna and scenic beauty of Chile.</p><p> </p>
Crecimiento de mezquite en vivero bajo diferentes condiciones de sustrato, riego y retenedores de humedad
Authors: Cervantes-Rodríguez Natalia , Prieto-Ruíz José A. , Rosales-Mata Sergio , Félix-Herrán Jaime A. 
Published: December 2017

Introducción: En el norte de México, el mezquite es utilizado ampliamente en las reforestaciones. La producción de planta de calidad es necesaria para su establecimiento en campo. Objetivo: Evaluar el efecto de distintas dosis de retenedores de humedad, mezclas de sustrato y frecuencias de riego sobre el crecimiento de Prosopis laevigata. Materiales y métodos: Se evaluó el efecto de cinco dosis de retenedores de humedad (0.0,1.5, 3.0, 4.5 y 6.0 g·L-1), dos frecuencias de riego (cada 48 y 96 h) y dos mezclas de sustratos (mezcla base [peat moss 55 % + vermiculita 24 % + agrolita 21 %]) y corteza composteada [50 %] + peat moss [50 %]). Las plantas de mezquite se evaluaron a los tres meses de edad en un diseño experimental en bloques al azar con arreglo factorial. Resultados y discusión: Los factores, tanto individuales como en interacción, ocasionaron diferencias significativas (P < 0.05) en la altura, diámetro y biomasa de la planta. Los mejores resultados se obtuvieron utilizando mezcla base, riego cada 48 h y retenedores de humedad en dosis de 1.5, 4.5 o 6.0 g·L-1. El sustrato fue el factor más influyente. Conclusión: El crecimiento de P. laevigata se favorece al combinar el tipo de sustrato, la frecuencia de riego y la dosis de retenedor de humedad adecuadamente.
Relación de la estructura celular de la madera de teca (Tectona grandis L. f.) con diferentes edades y sitios de crecimiento
Authors: Rodríguez-Anda Raúl , Fuentes-Talavera Francisco J. , Silva-Guzmán José A. , Palacios-Juárez Hilda , Turrado-Saucedo José 
Published: December 2017

Introducción: Las características celulares de la madera determinan las condiciones de procesamiento y uso de las especies forestales. Objetivo: Estudiar la variación de las características anatómicas en la parte interna y externa del duramen de Tectona grandis L. f. de diferentes edades y procedencias. Materiales y métodos: Se seleccionaron árboles de Campeche (9 y 15 años), Tabasco (15 años) y Chiapas (21 años). Se hicieron cortes (10 y 20 μm de espesor) de las caras anatómicas (transversal, radial y tangencial) de la madera y se observaron en microscopio de campo claro. Las imágenes se capturaron con el software Matrox PC-VCR versión 02.10.10. Los elementos celulares se midieron con el software ArcView GIS 3.2. Resultados y discusión: La madera de teca tuvo de 6 a 8 vasos·mm-.. La madera de Campeche (9 y 15 años) presentó el mayor diámetro de vasos en la parte interna y externa del duramen; en su parte interna, tuvo el mayor ancho de radios. En ambas partes del duramen, la madera de 9 años de Campeche tuvo mayor altura de radios; la madera de Chiapas de 21 años presentó mayor longitud y diámetro de fibras; y la madera de 15 años de Tabasco produjo el mayor espesor de pared de fibras. Conclusiones: La edad y procedencia inciden sobre la estructura celular de la madera de teca.
Reviewer Acknowledgements for International Business Research, Vol. 11, No. 1
Authors: Duran Kevin 
Published: December 2017

International Business Research wishes to acknowledge the following individuals for their assistance with peer review of manuscripts for this issue. Their help and contributions in maintaining the quality of the journal are greatly appreciated.International Business Research is recruiting reviewers for the journal. If you are interested in becoming a reviewer, we welcome you to join us. Please find the application form and details at http://recruitment.ccsenet.org and e-mail the completed application form to ibr@ccsenet.org.Reviewers for Volume 11, Number 1 Alireza Athari, Eastern Mediterranean University, IranAnca Gabriela Turtureanu, “DANUBIUS” University Galati, RomaniaAshford C Chea, Benedict College, USAAurelija Burinskiene, Vilnius Gediminas Technical University, LithuaniaBenjamin James Inyang, University of Calabar, NigeriaCelina Maria Olszak, University of Economics in Katowice, PolandEva Mira Bolfíková, Univerzity of P. J. Šafárik in Košice, Slovak RepublicFevzi Esen, Istanbul Medeniyet University, TurkeyFilomena Izzo, University of Campania Luigi Vanvitelli, ItalyFlorin Ionita, The Bucharest Academy of Economic Studies, RomaniaFrancesco Ciampi, Florence University, ItalyGiuseppe Granata, University of Cassino and Southen Lazio, ItalyGuillaume Marceau, University of Aix-Marseille, FranceGuo Zi-Yi, Wells Fargo Bank, N.A., USAHanna Trojanowska, Warsaw University of Technology, PolandHeather Cooper Bisalski, Dalton State College, USAHuijian Dong, Pacific University, USAJanusz Wielki, University of Business in Wroclaw, PolandJolita Vveinhardt, Vytautas Magnus University, LithuaniaJorge Mongay-Hurtado, ESIC Business and Marketing School, SpainKaren Gulliver, Argosy University, Twin Cities, USAMaria J. Sanchez-Bueno, Universidad Carlos III se Madrid, SpainMaria-Madela Abrudan, University of ORADEA, RomaniaMithat Turhan, Mersin University, TurkeyMohamed Abdel Rahman Salih, Taibah University, Saudi ArabiaMuath Eleswed, American University of Kuwait, USAPascal Stiefenhofer, University of Brighton, UKRafael Hernandez Barros, Universidad Complutense de Madrid, SpainRaphaël Dornier, Université Savoie Mont Blanc, FranceRoberto Campos da Rocha Miranda, University Center Iesb, BrazilSerhii Kozlovskiy, Donetsk National University, UkraineShun Mun Helen Wong, The Hong Kong Polytechnic University, Hong KongSumathisri Bhoopalan, Sastra University, IndiaValeria Stefanelli, Università del Salento, ItalyWing-Keung Wong, Asia University, Taiwan, China
Disentangling Diagenesis From the Rock Record: An Example From the Permo‐Triassic Wordie Creek Formation, East Greenland
Authors: Roberts J. , Turchyn A. V. , Wignall P. B. , Newton R. J. , Vane C. H. 
Published: December 2017

AbstractThe measurement of isotope ratios in sedimentary rocks deposited over geological time can provide key insights to past environmental change over important intervals in the past. However, it is important to be aware that secondary alteration can overprint the original isotopic records. We demonstrate this principle using high‐resolution carbon, sulfur, and oxygen isotope measurements in organic carbon, pyrite, and carbonate minerals (δ13Corg, δ34Spyr, δ34SCAS, δ13Ccarb, and δ18Ocarb) and kerogen analyses (HI and OI) from the Wordie Creek Formation, East Greenland. These sediments were initially deposited across the Permo‐Triassic transition, but as we will show, the carbonate record has been altered by interaction with meteoric water significantly after initial deposition. Comparison of the better preserved organic carbon and pyrite records with a proximal Permo‐Triassic sequence reveals significant pyrite‐sulfur isotope variability across the Permo‐Triassic transition. This regional heterogeneity argues against basin‐wide euxinia and instead suggests localized changes in sulfur fractionation in response to variations in organic carbon flux. This hypothesis can be used to explain seemingly inconsistent regional trends in other sulfur isotopes across the Permo‐Triassic transition.
Current and Future Decadal Trends in the Oceanic Carbon Uptake Are Dominated by Internal Variability
Authors: Li Hongmei , Ilyina Tatiana 
Published: December 2017

AbstractWe investigate the internal decadal variability of the ocean carbon uptake using 100 ensemble simulations based on the Max Planck Institute Earth system model (MPI‐ESM). We find that on decadal time scales, internal variability (ensemble spread) is as large as the forced temporal variability (ensemble mean), and the largest internal variability is found in major carbon sink regions, that is, the 50–65°S band of the Southern Ocean, the North Pacific, and the North Atlantic. The MPI‐ESM ensemble produces both positive and negative 10 year trends in the ocean carbon uptake in agreement with observational estimates. Negative decadal trends are projected to occur in the future under RCP4.5 scenario. Due to the large internal variability, the Southern Ocean and the North Pacific require the most ensemble members (more than 53 and 46, respectively) to reproduce the forced decadal trends. This number increases up to 79 in future decades as CO2 emission trajectory changes.
Prediction of the Midlatitude Response to Strong Madden‐Julian Oscillation Events on S2S Time Scales
Authors: Tseng K.‐C. , Barnes E. A. , Maloney E. D. 
Published: December 2017

AbstractThe Madden‐Julian Oscillation (MJO) forces strong variations in extratropical atmospheric circulations that have important implications for subseasonal‐to‐seasonal (S2S) prediction. In particular, certain MJO phases are characterized by a consistent modulation of geopotential height in the North Pacific and adjacent regions across different MJO events. Until recently, only limited research has examined the relationship between these robust MJO tropical‐extratropical teleconnections and model prediction skill. In this study, reanalysis data and numerical forecast model ensemble hindcasts are used to demonstrate that robust teleconnections in specific MJO phases and time lags are also characterized by excellent agreement in the prediction of geopotential height anomalies across model ensemble members at forecast leads of up to 3 weeks. These periods of enhanced prediction capabilities extend the possibility for skillful extratropical weather prediction beyond traditional 10–13 day limits.
The Impact of Parametric Uncertainties on Biogeochemistry in the E3SM Land Model
Authors: Ricciuto Daniel , Sargsyan Khachik , Thornton Peter 
Published: December 2017

AbstractWe conduct a global sensitivity analysis (GSA) of the Energy Exascale Earth System Model (E3SM), land model (ELM) to calculate the sensitivity of five key carbon cycle outputs to 68 model parameters. This GSA is conducted by first constructing a Polynomial Chaos (PC) surrogate via new Weighted Iterative Bayesian Compressive Sensing (WIBCS) algorithm for adaptive basis growth leading to a sparse, high‐dimensional PC surrogate with 3,000 model evaluations. The PC surrogate allows efficient extraction of GSA information leading to further dimensionality reduction. The GSA is performed at 96 FLUXNET sites covering multiple plant functional types (PFTs) and climate conditions. About 20 of the model parameters are identified as sensitive with the rest being relatively insensitive across all outputs and PFTs. These sensitivities are dependent on PFT, and are relatively consistent among sites within the same PFT. The five model outputs have a majority of their highly sensitive parameters in common. A common subset of sensitive parameters is also shared among PFTs, but some parameters are specific to certain types (e.g., deciduous phenology). The relative importance of these parameters shifts significantly among PFTs and with climatic variables such as mean annual temperature.
Full Coupling Between the Atmosphere, Surface, and Subsurface for Integrated Hydrologic Simulation
Authors: Davison Jason Hamilton , Hwang Hyoun‐Tae , Sudicky Edward A. , Mallia Derek V. , Lin John C. 
Published: December 2017

AbstractAn ever increasing community of earth system modelers is incorporating new physical processes into numerical models. This trend is facilitated by advancements in computational resources, improvements in simulation skill, and the desire to build numerical simulators that represent the water cycle with greater fidelity. In this quest to develop a state‐of‐the‐art water cycle model, we coupled HydroGeoSphere (HGS), a 3‐D control‐volume finite element surface and variably saturated subsurface flow model that includes evapotranspiration processes, to the Weather Research and Forecasting (WRF) Model, a 3‐D finite difference nonhydrostatic mesoscale atmospheric model. The two‐way coupled model, referred to as HGS‐WRF, exchanges the actual evapotranspiration fluxes and soil saturations calculated by HGS to WRF; conversely, the potential evapotranspiration and precipitation fluxes from WRF are passed to HGS. The flexible HGS‐WRF coupling method allows for unique meshes used by each model, while maintaining mass and energy conservation between the domains. Furthermore, the HGS‐WRF coupling implements a subtime stepping algorithm to minimize computational expense. As a demonstration of HGS‐WRF's capabilities, we applied it to the California Basin and found a strong connection between the depth to the groundwater table and the latent heat fluxes across the land surface.
Biomimetic Copper Sulfide for Chemo‐Radiotherapy: Enhanced Uptake and Reduced Efflux of Nanoparticles for Tumor Cells under Ionizing Radiation
Authors: Yi Xuan , Chen Lei , Chen Jie , Maiti Debabrata , Chai Zhifang , Liu Zhuang , Yang Kai 
Published: December 2017

AbstractCombined chemo‐radiotherapy is one of most widely applied treatments for clinical cancer therapy. Herein, it is found in this carefully designed study that ionizing radiation (e.g., X‐ray) can significantly increase the cell uptake of many different types of nanoparticles, and meanwhile obviously reduce their efflux. Such a phenomenon, which is not observed for small molecule drug such as doxorubicin (DOX), may be attributed to the X‐ray‐induced cell cycle change and upregulation of Caveolin‐1, a key protein in the caveolin‐dependent endocytosis pathway. Biomimetic copper sulfide nanoparticles, which are synthesized using melanin as the template and functionalized with polyethylene glycol (PEG), are then chosen as a platform for the combined chemo‐radiotherapy. Such CuS@Melanin‐PEG nanoparticles, while being able to load chemotherapeutics (e.g., DOX), can also act as a radiosensitizer to promote X‐ray induced cell apoptosis. In addition, although the overall tumor accumulation of CuS@Melanin‐PEG/DOX post intravenous injection is not significantly changed for tumors exposed to X‐ray, X‐ray radiation can result in obviously increased tumor cell uptake of drug‐loaded nanoparticles, subsequently leading to excellent synergistic antitumor therapeutic effect. A nanoplatform is developed with great performance in chemo‐radiotherapy, as well as uncovers a general synergistic mechanism particularly suitable for nanoparticle‐based chemo‐radiotherapy.
Mg–Al and Zn–Al Layered Double Hydroxides Promote Dynamic Expression of Marker Genes in Osteogenic Differentiation by Modulating Mitogen‐Activated Protein Kinases
Authors: Kang Ha Ram , da Costa Fernandes Célio Junior , da Silva Rodrigo Augusto , Constantino Vera Regina Leopoldo , Koh Ivan Hong Jun , Zambuzzi Willian F. 
Published: December 2017

AbstractThe effect of LDH samples comprised of chloride anions intercalated between positive layers of magnesium/aluminum (Mg‐Al LDH) or zinc/aluminum (Zn‐Al LDH) chemical composition on pre‐osteoblast performance is investigated. Non‐cytotoxic concentrations of both LDHs modulated pre‐osteoblast adhesion by triggering cytoskeleton rearrangement dependent on recruiting of Cofilin, which is modulated by the inhibition of the Protein Phosphatase 2A (PP2A), culminating in osteoblast differentiation with a significant increase of osteogenic marker genes. The alkaline phosphatase (ALP) and bone sialoprotein (BSP) are significantly up‐modulated by both LDHs; however, Mg‐Al LDH nanomaterial promoted even more significance than both experimental controls, while the phosphorylations of mitogen‐activated protein kinase (MAPKs)‐ extracellular signal–regulated kinases (ERK) and c‐Jun N‐terminal kinase (JNK) significantly increased. MAPK signaling is necessary to activate Runt‐related transcription factor 2 (RUNX2) gene. Concomitantly, it is also investigated whether challenged osteoblasts are able to modulate osteoclastogenesis by investigating both osteoprotegerin (OPG) and Receptor activator of nuclear factor kappa‐ligand (RANKL) in this model; a dynamic reprogramming of both these genes is found, suggesting LDHs in modulating osteoclastogenesis. These results suggest that LDHs interfere in bone remodeling, and they can be considered as nanomaterials in graft‐based bone healing or drug‐delivery materials for bone disorders.
Convenient Monitoring System of Intracellular microRNA Expression during Adipogenesis via Mechanical Stimulus‐Induced Exocytosis of Lipovesicular miRNA Beacon
Authors: Han Seungmin , Kang Byunghoon , Jang Eunji , Ki Jisun , Kim Eunjung , Jeong Mun‐Young , Huh Yong‐Min , Son Hye‐Young , Haam Seungjoo 
Published: December 2017

AbstractNoninvasive investigation of microRNAs (miRNAs) expression, which is deeply related to biological phenomena such as stem cell differentiation, in culture soup is particularly useful for monitoring of stem cell differentiation without phototoxicity of living cells, especially when cell morphologies remain unchanged during differentiation. However, real‐time detection of miRNA in culture soup is not recommended because of insufficient miRNA amounts in culture soup. In this study, a convenient method is introduced for real‐time assessing intracellular miRNA in culture soup by using lipovesicular miRNA beacon (Lipo‐mB) and mechanical stimulus‐mediated exocytosis. Pipetting‐harvest of culture soup induces exocytosis‐secretion of fluorescence signal of Lipo‐mB from cytoplasm into culture soup. To demonstrate this method, Lipo‐mB is applied for monitoring of adipogenesis by analyzing the expression levels of various intracellular miRNAs, which are related to adipogenesis regulators. The fluorescence intensity profile of the culture soup is correlated with the quantitative reverse‐transcription‐polymerase chain reaction data and absorbance of Oil Red O staining. These results demonstrate that Lipo‐mB can successfully monitor stem cell differentiation by sensing changes in miRNA expression from culture soup of living cells. Lipo‐mB can be further developed as an accurate sensing system for analyzing subtle differences in genotype, even when changes in phenotype cannot be observed.
Emerging Biotechnology Applications of Aqueous Two‐Phase Systems
Authors: Teixeira Alyne G. , Agarwal Rishima , Ko Kristin Robin , Grant‐Burt Jessica , Leung Brendan M. , Frampton John P. 
Published: December 2017

AbstractLiquid–liquid phase separation between aqueous solutions containing two incompatible polymers, a polymer and a salt, or a polymer and a surfactant, has been exploited for a wide variety of biotechnology applications throughout the years. While many applications for aqueous two‐phase systems fall within the realm of separation science, the ability to partition many different materials within these systems, coupled with recent advances in materials science and liquid handling, has allowed bioengineers to imagine new applications. This progress report provides an overview of the history and key properties of aqueous two‐phase systems to lend context to how these materials have progressed to modern applications such as cellular micropatterning and bioprinting, high‐throughput 3D tissue assembly, microscale biomolecular assay development, facilitation of cell separation and microcapsule production using microfluidic devices, and synthetic biology. Future directions and present limitations and design considerations of this adaptable and promising toolkit for biomolecule and cellular manipulation are further evaluated.
Recent Progress in Developing Injectable Matrices for Enhancing Cell Delivery and Tissue Regeneration
Authors: Tong Xinming , Yang Fan 
Published: December 2017

AbstractBiomaterials are key factors in regenerative medicine. Matrices used for cell delivery are especially important, as they provide support to transplanted cells that is essential for promoting cell survival, retention, and desirable phenotypes. Injectable matrices have become promising and attractive due to their minimum invasiveness and ease of use. Conventional injectable matrices mostly use hydrogel precursor solutions that form solid, cell‐laden hydrogel scaffolds in situ. However, these materials are associated with challenges in biocompatibility, shear‐induced cell death, lack of control over cellular phenotype, lack of macroporosity and remodeling, and relatively weak mechanical strength. This Progress Report provides a brief overview of recent progress in developing injectable matrices to overcome the limitations of conventional in situ hydrogels. Biocompatible chemistry and shear‐thinning hydrogels have been introduced to promote cell survival and retention. Emerging investigations of the effects of matrix properties on cellular function in 3D provide important guidelines for promoting desirable cellular phenotypes. Moreover, several novel approaches are combining injectability with macroporosity to achieve macroporous, injectable matrices for cell delivery.
Tension‐Activated Delivery of Small Molecules and Proteins from Superhydrophobic Composites
Authors: Wang Julia , Colson Yolonda L. , Grinstaff Mark W. 
Published: December 2017

AbstractThe fabrication and performance of mechanically responsive multilayer superhydrophobic composites are reported. The application of tensile strain triggers the release of small molecules and proteins from these composites, with different tensile strain magnitudes and coating thickness influencing agent release. These mechanoresponsive composites consist of an absorbent drug core surrounded by an electrosprayed superhydrophobic protective coating that limits drug release in the absence of tensile strain. Coating thickness and applied tensile strain control release of chemotherapeutic cisplatin and enzyme β‐galactosidase, as measured by atomic absorption and UV–vis spectrophotometry, respectively, with preserved in vitro activity. Such mechanically responsive drug delivery devices, when coupled to existing dynamic mechanical forces in the body or integrated with mechanical medical devices, such as stents, will provide local controlled dosing.