bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of heart pulsatile on the measurement of artery bioimpedance
Authors: Abdelbaset Reda , Dosoky Mohamed El , El-Wakad Mohamed T. 
Published: January 2018

Abstract
Bioimpedance is an electrical property, which is measured to indicate related parameters and diagnose several diseases of the body. The heart pulsatile is a blood flow with periodic variations as a result of heart beats. The main objective of this article is studying the effect of the heart pulsatile on the measurements of artery bioimpedance. However, neglecting the heart pulsatile leads to error in calculations of many applications based on artery bioimpedance measurement such as glucose monitoring, stenosis, and cholesterol detection. Furthermore, the studying of the heart pulsatile effect could be developed to measure the heart rate as a novel method based on bioimpedance phenomena. A simple model of electrodes and composite layers (skin, fat, muscle, and artery) is simulated using COMSOL. In this work, a model of noninvasive electrodes for measuring an artery bioimpedance is described to show the best method to take into consideration the effect of heart pulsatile.
Redemoinho infinito: Schwanke e seu livro de artista
Authors: Alcântara Dalva Maria Alves , Lamas Nadja De Carvalho 
Published: January 2018

Este artigo tem por proposta explorar o conceito de arquivo sob a perspectiva de Jacques Derrida, em seu “Mal de Arquivo – Uma impressão freudiana”, a partir da análise do Livro de Artista de Luiz Henrique Schwanke. Derrida correlaciona a noção de arquivo com a memória (pessoal e histórica), enfatizando a tensão constante entre a sua manutenção e a sua repressão (consciente ou inconsciente); e o “mal de arquivo” com a pulsão de morte, com o apagamento da memória, e suas possíveis consequências psíquicas, sociais e políticas. A partir dessa obra de Schwanke, uma série de pinturas conformadas num livro objeto de arte, um “livro de artista”, serão feitas ponderações quanto à significância do arquivamento como um recurso na poética do artista. Recebido em: 15 novembro 2017Aprovado em: 06 dezembro 2017
A VIOLÊNCIA DE GÊNERO NA PERCEPÇÃO DE AGENTES COMUNITÁRIOS DE SAÚDE
Authors: Moura Ludmila De , Castro-Silva Carlos Roberto 
Published: January 2018

A violência é um fenômeno que atinge a ambos os sexos, porém têm incidência especial sobre mulheres, negras e pobres. O Brasil encontra-se no 5º lugar em relação a 83 países. Entre 2003 e 2013 houve um aumento de 21% no número de mulheres assassinadas, representando 13 feminicídios por dia. Esta pesquisa teve por objetivo compreender as percepções e os sentidos atribuídos ao fenômeno da violência de gênero no âmbito doméstico, contra a mulher, a partir das práticas dos/as agentes comunitários de saúde (ACS) em ações em território de alta vulnerabilidade social. Os achados foram analisados baseados nos pressupostos da psicologia sócio histórica e da epistemologia qualitativa de González Rey. Através da observação participante, a pesquisadora acompanhou os/as em visitas domiciliares, que resultou na elaboração de 20 diários de campo, além de entrevistas abertas com duas ACS. Os resultados obtidos foram analisados pela categoria empírica “Violência de Gênero”, segundo duas óticas: “ser mulher” e “a violência por parceiro íntimo”. A “naturalização” da violência na comunidade também foi problematizada, juntamente com o patriarcado enquanto discurso normativo articulado com o capitalismo, na busca de explicação da opressão das mulheres pelos homens. Palavras-chave: Agente comunitário de saúde; Gênero; Violência de gênero; Trabalho em saúde; Vulnerabilidade social.
Developmental effects of environmental light on male nuptial coloration in Lake Victoria cichlid fish
Authors: Wright Daniel Shane , Rietveld Emma , Maan Martine E. 
Published: January 2018

BackgroundEfficient communication requires that signals are well transmitted and perceived in a given environment. Natural selection therefore drives the evolution of different signals in different environments. In addition, environmental heterogeneity at small spatial or temporal scales may favour phenotypic plasticity in signaling traits, as plasticity may allow rapid adjustment of signal expression to optimize transmission. In this study, we explore signal plasticity in the nuptial coloration of Lake Victoria cichlids,Pundamilia pundamiliaandPundamilia nyererei.These two species differ in male coloration, which mediates species-assortative mating. They occur in adjacent depth ranges with different light environments. Given the close proximity of their habitats, overlapping at some locations, plasticity in male coloration could contribute to male reproductive success but interfere with reproductive isolation.MethodsWe rearedP. pundamilia,P. nyererei,and their hybrids under light conditions mimicking the two depth ranges in Lake Victoria. From photographs, we quantified the nuptial coloration of males, spanning the entire visible spectrum. In experiment 1, we examined developmental colour plasticity by comparing sibling males reared in each light condition. In experiment 2, we assessed colour plasticity in adulthood, by switching adult males between conditions and tracking coloration for 100 days.ResultsWe found that nuptial colour inPundamiliadid respond plastically to our light manipulations, but only in a limited hue range. Fish that were reared in light conditions mimicking the deeper habitat were significantly greener than those in conditions mimicking shallow waters. The species-specific nuptial colours (blue and red) did not change. When moved to the opposing light condition as adults, males did not change colour.DiscussionOur results show that species-specific nuptial colours, which are subject to strong divergent selection by female choice, are not plastic. We do find plasticity in green coloration, a response that may contribute to visual conspicuousness in darker, red-shifted light environments. These results suggest that light-environment-induced plasticity in male nuptial coloration inP. pundamiliaandP. nyerereiis limited and does not interfere with reproductive isolation.
Quasi‐Monolayer Black Phosphorus with High Mobility and Air Stability
Authors: Tan Sherman Jun Rong , Abdelwahab Ibrahim , Chu Leiqiang , Poh Sock Mui , Liu Yanpeng , Lu Jiong , Chen Wei , Loh Kian Ping 
Published: January 2018

AbstractBlack phosphorus (BP) exhibits thickness‐dependent band gap and high electronic mobility. The chemical intercalation of BP with alkali metal has attracted attention recently due to the generation of universal superconductivity regardless of the type of alkali metals. However, both ultrathin BP, as well as alkali metal‐intercalated BP, are highly unstable and corrode rapidly under ambient conditions. This study demonstrates that alkali metal hydride intercalation decouples monolayer to few layers BP from the bulk BP, allowing an optical gap of ≈1.7 eV and an electronic gap of 1.98 eV to be measured by photoluminescence and electron energy loss spectroscopy at the intercalated regions. Raman and transport measurements confirm that chemically intercalated BP exhibits enhanced stability, while maintaining a high hole mobility of up to ≈800 cm2 V−1 s−1 and on/off ratio exceeding 103. The use of alkali metal hydrides as intercalants should be applicable to a wide range of layered 2D materials and pave the way for generating highly stable, quasi‐monolayer 2D materials.
Roadmap for a Smart Factory: A Modular, Intelligent Concept for the Production of Specialty Chemicals
Authors: Reitze Arnulf , Jürgensmeyer Nikolas , Lier Stefan , Kohnke Marco , Riese Julia , Grünewald Marcus 
Published: January 2018

AbstractDigitalization and increasing the flexibility of production concepts offer the possibility to react to market challenges in the field of specialty chemicals. Shorter product lifetimes, increasing product individualization, and the resulting market volatility impose new requirements on plant operators. Novel concepts such as modular production plants and developments in digitalization (Industry 4.0) are able to assist the implementation of smart factories in specialty chemicals. These essential concepts will be presented in this Minireview.
The Binding Mode of a Tau Peptide with Tubulin
Authors: Kadavath Harindranath , Cabrales Fontela Yunior , Jaremko Mariusz , Jaremko Łukasz , Overkamp Kerstin , Biernat Jacek , Mandelkow Eckhard , Zweckstetter Markus 
Published: January 2018

AbstractThe microtubule‐associated protein Tau promotes the polymerization of tubulin and modulates the function of microtubules. As a consequence of the dynamic nature of the Tau–tubulin interaction, the structural basis of this complex has remained largely elusive. By using NMR methods optimized for ligand–receptor interactions in combination with site‐directed mutagenesis we demonstrate that the flanking domain downstream of the four microtubule‐binding repeats of Tau binds competitively to a site on the α‐tubulin surface. The binding process is complex, involves partial coupling of different interacting regions, and is modulated by phosphorylation at Y394 and S396. This study strengthens the hypothesis of an intimate relationship between Tau phosphorylation and tubulin binding and highlights the power of the INPHARMA NMR method to characterize the interaction of peptides derived from intrinsically disordered proteins with their molecular partners.
Detection of monohydroxylated polycyclic aromatic hydrocarbons in urine and particulate matter using LC separations coupled with integrated SPE and fluorescence detection or coupled with high‐resolution time‐of‐flight mass spectrometry
Authors: Lintelmann Jutta , Wu Xiao , Kuhn Evelyn , Ritter Sebastian , Schmidt Claudia , Zimmermann Ralf 
Published: January 2018

AbstractA high‐performance liquid chromatographic (HPLC) method with integrated solid‐phase extraction for the determination of 1‐hydroxypyrene and 1‐, 2‐, 3‐, 4‐ and 9‐hydroxyphenanthrene in urine was developed and validated. After enzymatic treatment and centrifugation of 500 μL urine, 100 μL of the sample was directly injected into the HPLC system. Integrated solid‐phase extraction was performed on a selective, copper phthalocyanine modified packing material. Subsequent chromatographic separation was achieved on a pentafluorophenyl core–shell column using a methanol gradient. For quantification, time‐programmed fluorescence detection was used. Matrix‐dependent recoveries were between 94.8 and 102.4%, repeatability and reproducibility ranged from 2.2 to 17.9% and detection limits lay between 2.6 and 13.6 ng/L urine. A set of 16 samples from normally exposed adults was analyzed using this HPLC‐fluorescence detection method. Results were comparable with those reported in other studies. The chromatographic separation of the method was transferred to an ultra‐high‐performance liquid chromatography pentafluorophenyl core–shell column and coupled to a high‐resolution time‐of‐flight mass spectrometer (HR‐TOF‐MS). The resulting method was used to demonstrate the applicability of LC‐HR‐TOF‐MS for simultaneous target and suspect screening of monohydroxylated polycyclic aromatic hydrocarbons in extracts of urine and particulate matter.
Bioinspired Electro‐Organocatalytic Material Efficient for Hydrogen Production
Authors: Moral Octavio González‐del , Call Arnau , Franco Federico , Moya Alicia , Nieto‐Rodríguez Jose Antonio , Frias María , Fierro Jose L. G. , Costas Miquel , Lloret‐Fillol Julio , Alemán José , Mas‐Ballesté Rubén 
Published: January 2018

AbstractCommercial carbon fibers can be used as electrodes with high conductive surfaces in reduced devices. Oxidative treatment of such electrodes results in a chemically robust material with high catalytic activity for electrochemical proton reduction, enabling the measurement of quantitative faradaic yields (>95 %) and high current densities. Combination of experiments and DFT calculations reveals that the presence of carboxylic groups triggers such electrocatalytic activity in a bioinspired manner. Analogously to the known Hantzsch esters, the oxidized carbon fiber material is able to transfer hydrides, which can react with protons, generating H2, or with organic substrates resulting in their hydrogenation. A plausible mechanism is proposed based on DFT calculations on model systems.
Stereochemical and Steric Control of Photophysical and Chiroptical Properties in Bichromophoric Systems
Authors: Blázquez‐Moraleja Alberto , Cerdán Luis , García‐Moreno Inmaculada , Avellanal‐Zaballa Edurne , Bañuelos Jorge , Jimeno M. Luisa , López‐Arbeloa Iñigo , Chiara Jose Luis 
Published: January 2018

AbstractStereochemical and steric control of the relative spatial arrangement of the chromophoric units in multichromophoric systems offers an interesting strategy for raising unusual and appealing light‐induced emission states. To explore and exploit this strategy, a series of conformationally restricted boron–dipyrromethene (BODIPY) dimers were designed by using tartaric acid as a symmetrical connector between the boron atoms of the dyes. The variety of stereoisomeric forms available for this bis(hydroxy acid) allows the relative spatial orientation of the chromophoric units in the dimer to be modified, which thus opens the door to modulation of the photophysical and chiroptical properties of the new bichromophoric systems. Chromophore alkylation introduces an additional level of control through distance‐dependent steric interactions between the BODIPY units in the dimer, which also modulates their relative spatial disposition and properties.
A Unique (3+2) Annulation Reaction between Meldrum's Acid and Nitrones: Mechanistic Insight by ESI‐IMS‐MS and DFT Studies
Authors: Lespes Nicolas , Pair Etienne , Maganga Clisy , Bretier Marie , Tognetti Vincent , Joubert Laurent , Levacher Vincent , Hubert‐Roux Marie , Afonso Carlos , Loutelier‐Bourhis Corinne , Brière Jean‐François 
Published: January 2018

AbstractThe fragile intermediates of the domino process leading to an isoxazolidin‐5‐one, triggered by unique reactivity between Meldrum's acid and an N‐benzyl nitrone in the presence of a Brønsted base, were determined thanks to the softness and accuracy of electrospray ionization mass spectrometry coupled to ion mobility spectrometry (ESI‐IMS‐MS). The combined DFT study shed light on the overall organocatalytic sequence that starts with a stepwise (3+2) annulation reaction that is followed by a decarboxylative protonation sequence encompassing a stereoselective pathway issue.
Fluorescence detected linear dichroism spectroscopy: A selective and sensitive probe for fluorophores in flow‐oriented systems
Authors: Wemyss Alan M. , Chmel Nikola P. , Lobo Daniela P. , Sutherland John A. , Dafforn Timothy R. , Rodger Alison 
Published: January 2018

AbstractFluorescence detection typically enhances sensitivity and selectivity for fluorescent analytes. The potential for combining fluorescence detection with flow orientation of the sample in the normal configuration of linear dichroism experiments is explored in this work by measuring the fluorescence emitted from flow‐orientated DNA‐bound ligands and M13 bacteriophage. Data for ethidium bromide, Hoechst 33258, and 4,6‐diamidino‐2‐phenyindole are presented. The theoretical basis of the technique is also presented for instruments running in both the fixed direct‐current mode, which is the normal operation mode of circular dichroism spectropolarimeters, and also in fixed high‐tension voltage mode. The role of the stray light reaching the detector that results in a spectral shape in fixed direct current mode that resembles the shape of a linear dichroism spectrum, rather than the expected reduced linear dichroism, is also explored.
The influence of microbial communities for triadimefon enantiomerization in soils with different pH values
Authors: Mohamed Ahmed Talab Khaled , Yang Zhong‐Hua , Li Jian‐Hong , Zhao Yue , Alrasheed Mohamed Omer Sara , Xiong Ya‐Bing 
Published: January 2018

AbstractEnantiomers of chiral molecules can undergo interconversion leading to markedly different toxicities, which can introduce significant uncertainty when evaluating biological and environmental fates. However, enantiomerization (the reversible conversion of one enantiomer into the other) related to soil microorganism is rarely understood. For better understanding, S‐triadimefon and R‐triadimefon enantiopure were incubated in different soils with different pH value. Both high‐performance liquid chromatography and high‐throughput sequencing technology were used to explore target analytes quantitatively and microbial taxa related to the conversion process. Results revealed a significant enantiomerization among the soils. The alkaline soil from Beijing had a faster conversion than neutral soil from Changchun, while acidic soil from Wuhan had no conversion. At the same results, analysis of bacteria community showed higher abundance of Arthrobacter and Halomonas genus in alkaline soil than neutral soil after treatments, but the acidic soil was lower. Moreover, Arthrobacter and Halomonas were responsible for converting S‐triadimefon to R‐triadimefon and R‐triadimefon to S‐triadimefon in alkaline and neutral soil, respectively. Thus, these genera may be one of the reasons to explain the enantiomerization in different soils observed in this study. Thus, research at microbial level is necessary for efficient ecological risk assessment of chiral fungicide.
Mapping Perfluoroalkyl Effects in Togni‐Type Reagents by Thermolysis
Authors: Santschi Nico , Katayev Dmitry , Calvo Roxan , Jelier Benson J. 
Published: January 2018

AbstractWe present the thermolysis of cyclic hypervalent iodine(III) perfluoroalkyl transfer reagents carried out in standard GC‐MS instrumentation. Through heating, these structures undergo fragmentation to afford perfluoroalkyl radicals F2n+1Cn. and each reagent can be characterized by means of a threshold temperature, TIP(n). This parameter TIP(n) not only reflects the stability of the F2n+1Cn–I bond, but potentially also carries information regarding fundamental properties of the linear perfluoroalkyl chains.
Automatic fast double KNN classification algorithm based on ACC and hierarchical clustering for big data
Authors: Li Haiyun , Li Haifeng , Wei Kaibin 
Published: January 2018

SummaryIn data mining, k‐nearest neighbors (KNN) classifier is an efficient lazy learning yet simple widely renowned method, which has been widely used in many actual applications, successfully. Because of time and memory restrictions of KNN, when KNN is tested in large‐scale datasets, the classification accuracy is very low. Therefore, we propose an automatic fast double KNN classification algorithm on the basis of automatically determining the cluster centers and hierarchical clustering. We introduce automatically determining the cluster centers into the KNN in training process. Namely, big data samples are divided into several parts depending on our clustering methods. Afterwards, the clusters nearest to testing samples are excavated as the new training samples in the testing process. Each of the new samples is then conducted with hierarchical clustering. In this way, computation and time complexity are greatly reduced. Finally, experiments results conducted on big data show that new KNN classification method can significantly raise the accuracy and efficiency of automatic classification than other state‐of‐the‐art KNN classification algorithms.
Synthesis of boronate‐functionalized organic‐inorganic hybrid monolithic column for the separation of cis‐diol containing compounds at low pH
Authors: Zhao Heqing , Lyu Haixia , Qin Wenfei , Xie Zenghong 
Published: January 2018

AbstractIn this work, an organic‐inorganic hybrid boronate affinity monolithic column was prepared via “one‐pot” process using 4‐vinylphenylboronic acid as organic monomer and divinylbenzene as cross‐linker. The effects of reaction temperature, solvents and composition of organic monomers on the column properties (e.g. morphology, permeability, and mechanical stability) were investigated. A series of test compounds including small neutral molecules, aromatic amines, and cis‐diol compounds were used to evaluate the retention behaviors of the prepared hybrid monolithic column. The results demonstrated that the prepared hybrid monolith exhibited mixed‐interactions including hydrophilicity, cation exchange, and boronate affinity interaction. The run‐to‐run, day‐to‐day and batch‐to‐batch reproducibilities of the prepared hybrid monolith for thiourea's retention time were satisfactory with the relative standard deviations (RSDs) less than 0.09, 1.45 and 4.05% (n = 3), respectively, indicating the effectiveness and practicability of the proposed method.
Effects of copper on expression of methane monooxygenases, trichloroethylene degradation, and community structure in methanotrophic consortia
Authors: Xing Zhilin , Zhao Tiantao , Zhang Lijie , Gao Yanhui , Liu Shuai , Yang Xu 
Published: January 2018

AbstractCopper plays a key role in regulating the expression of enzymes that promote biodegradation of contaminants in methanotrophic consortia (MC). Here, we utilized MC isolated from landfill cover to investigate cometabolic degradation of trichloroethylene (TCE) at nine different copper (Cu2+) concentrations. The results demonstrated that an increase in Cu2+ concentration from 0 to 15 μM altered the specific first‐order rate constant k1,TCE, the expression levels of methane monooxygenase (pmoA and mmoX) genes, and the specific activity of soluble methane monooxygenase (sMMO). High efficiency TCE degradation (95%) and the expression levels of methane monooxygenase (MMO) were detected at a Cu2+ concentration of 0.03 μM. Notably, sMMO‐specific activity ranged from 74.41 nmol/(mgcell h) in 15 μM Cu2+ to 654.99 nmol/(mgcell h) in 0.03 μM Cu2+, which contrasts with cultures of pure methanotrophs in which sMMO activity is depressed at high Cu2+ concentrations, indicating a special regulatory role for Cu2+ in MC. The results of MiSeq pyrosequencing indicated that higher Cu2+ concentrations stimulated the growth of methanotrophic microorganisms in MC. These findings have important implications for the elucidation of copper‐mediated regulatory mechanisms in MC.
Anxiety symptoms predicted decline in episodic memory in cognitively healthy older adults: A 3‐year prospective study
Authors: Fung Ada Wai Tung , Lee Joyce Sau Wa , Lee Allen Ting Chun , Lam Linda Chiu Wa 
Published: January 2018

ObjectiveProspective studies on late‐life anxiety disorders suggested that history of anxiety symptoms may be predictive of cognitive decline in old age. However, the relationship between anxiety and cognitive decline is still inconclusive due to heterogeneity in sample and methodology. This study was to explore how baseline anxiety symptoms associated with the change of memory in older people without cognitive impairment over a 3‐year period.MethodsThis was a 3‐year prospective study on 91 cognitively normal older adults with anxiety symptoms. They were matched with 91 controls based on age, gender, and education. Anxiety symptoms were assessed with Revised Clinical Interview Schedule (CIS‐R). Physical health was assessed with Chronic Illness Rating Scale (CIRS). Cognitive performance was measured using Cantonese version of the mini‐mental state examination (CMMSE); 10‐minute delay recall; Category verbal fluency test (CVFT); Trail making tests (TMT); and digit and visual span tests. Outcomes were determined as the change of cognitive performance over a 3‐year period.ResultsAs expected, anxiety group had higher score in CIRS score (t = 4.45, P < .001) and CIS‐R score (t = 9.24, P < .001) than control group. Linear regression showed that baseline anxiety symptoms were associated with change in delayed recall (B = 0.77, P = 0.027, 95% CI = 0.09–1.46), after adjusting for cognitive performance, physical, and mental health statuses.ConclusionsAnxious healthy older adults showed specific decline in episodic memory over a 3‐year interval. Our result suggested that anxiety symptoms are predictive of episodic memory decline in cognitively healthy older adults and may be an early sign of neurodegenerative disorders.