bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Need to Optimize Adolescent Immunization
Authors: Bernstein Henry H. , Bocchini Joseph A. ,   COMMITTEE ON INFECTIOUS DISEASES, Byington Carrie L. , Maldonado Yvonne A. , Barnett Elizabeth D. , Campbell James D. , Davies H. Dele , Lynfield Ruth , Munoz Flor M. , Nolt Dawn , Nyquist Ann-Christine , O’Leary Sean , Rathore Mobeen H. , Sawyer Mark H. , Steinbach William J. , Tan Tina Q. , Zaoutis Theoklis E. 
Published: February 2017

This Clinical Report was retired January 2024.
The adolescent period heralds the pediatric patient’s transition into adulthood. It is a time of dynamic development during which effective preventive care measures can promote safe behaviors and the development of lifelong health habits. One of the foundations of preventive adolescent health care is timely vaccination, and every visit can be viewed as an opportunity to update and complete an adolescent’s immunizations.
In the past decade, the adolescent immunization schedule has expanded to include 2 doses of quadrivalent meningococcal conjugate vaccine, 1 dose of tetanus, diphtheria, acellular pertussis, absorbed vaccine, 2 or 3 doses of human papillomavirus vaccine, depending on the child’s age, and an annual influenza vaccine. In addition, during adolescent visits, health care providers can determine whether catch-up vaccination is needed to meet early childhood recommendations for hepatitis B; hepatitis A; measles, mumps, rubella; poliovirus; and varicella vaccines. New serogroup B meningococcal vaccines are now available for those at increased risk for meningococcal disease; in addition, these serogroup B meningococcal vaccines received a Category B recommendation for healthy adolescents, where individual counseling and risk–benefit evaluation based on health care provider judgements and patient preferences are indicated. This clinical report focuses on the epidemiology of adolescent vaccine-preventable diseases by reviewing the rationale for the annual universally recommended adolescent immunization schedule of the American Academy of Pediatrics, the American Academy of Family Physicians, the Centers for Disease Control and Prevention, and the American Congress of Obstetricians and Gynecologists. In addition, the barriers that negatively influence adherence to this current adolescent immunization schedule will be highlighted.
Calidad nutricional de Tithonia diversifolia Hemsl. A Gray bajo tres sistemas de siembra en el trópico alto.
Authors: Gallego-Castro Luis Alberto , Mahecha-Ledesma Liliana , Angulo-Arizala Joaquín 
Published: February 2017

El objetivo de este trabajo fue comparar la composición bromatológica y el contenido de taninos del forraje de botón de oro (Tithonia diversifolia) obtenido bajo tres sistemas de siembra. El trabajo se desarrolló en la nca Santa Martha, en el municipio de Guarne (Antioquia-Colombia), ubicada a 2453 msnm, entre octubre de 2013 y julio de 2014. A los 56 días del corte de uniformización, se analizaron los contenidos de materia seca (12,74%, 12,90%, 12,45%), proteína cruda (14,1%, 12,76%, 13,31%), cenizas (16,19%, 15,50%, 16,00), calcio (2,86%, 3,05%, 2,93%), fósforo (0,27%, 0,25%, 0,27%), bra detergente neutro (53,81%, 50,21%, 52,80%), bra detergente ácido (48,18%, 48,87%, 48,47%), carbohidratos totales no estructurales (8,50%, 8,35%, 7,82%), taninos totales (0,08%, 0,11%, 0,08%) y fenoles totales (0,20%, 0,29%, 0,24%), para plantas completas cosechadas en parcelas establecidas a partir de estacas, semilla sexual manejada in vitro y semilla sexual en almácigos, respectivamente; solo se encontraron diferencias para fenoles totales (p≤0,05). El método de establecimiento no incidió sobre el contenido de nutrientes bajo las condiciones en que se realizó este estudio, y al contenido de metabolitos secundarios no ser alto, se espera que no in uyan sobre la palatabilidad, el consumo ni la digestibilidad de la materia seca.
PENGARUH PERAMBANAN ECENG GONDOK (Eichhornia crassipes) OLEH IKAN KOAN (Ctenopharyngodon idella) TERHADAP KESUBURAN (N, P) DAN KELIMPAHAN FITOPLANKTON DI DANAU LIMBOTO
Authors: Krismono Krismono , M. F. Rahardjo M. F. Rahardjo , Harris Enang , Kartamihardja Endi Setiadi 
Published: February 2017

Pengendalian gulma air eceng gondok (Eichhornia crassipes) dengan ikan koan (Ctenopharyngodon idella) akan meningkatkan kesuburan perairan sebagai akibat sekresi dari ikan koan yang dikeluarkan di air. Penelitian mengenai pengaruh perambanan eceng gondok oleh ikan koan terhadap kesuburan perairan, N, P, dan kelimpahan fitoplankton di Danau Limboto perlu dilakukan. Penelitian ini bertujuan untuk mengkaji pengaruh perambanan ikan koan terhadap kesuburan perairan (N, P) dan kelimpahan fitoplankton di Danau Limboto. Metode penelitian dilakukan dengan percobaan menggunakan perlakuan pakan eceng gondok pada ikan koan. Rancanganpercobaan dengan rancangan acak lengkap dengan tiga ulangan dan satu kontrol. Hasil penelitian menunjukan bahwa laju perambanan ikan koan dengan kepadatan 100, 200, dan 400 ekor dengan biomassa eceng gondok 10 kg mempengaruhi peningkatan produktivitas perairan atau kesuburan (N dan P) dan kelimpahan fitoplankton. Kepadatan ikan koan 200 ekor adalah kepadatan yang paling efektif untuk pengendalian eceng gondok dibanding kepadatan 100 dan 400 ekor. To control of waterhyacinth (Eichhornia crassipes) using grass carp (Ctenopharyngodon idella) was fertilized in waters because of excresi of grass carp. The research is to knowed effect of grazing of grass carp to waterhyasinth to productivity and abundance of phytoplankton in Limboto Lake. Reseach Metodology is used experiment with rendom completed desaign with three treatmen with three replycation and one kontrol. The result each showed treatmen of stocking density 100, 200, 400 fish each cage, and fitoplankton abundance, stocking density 200 fish is cage increasing productivity, fitoplnkton abundance of lake. The treatmen stocking density 200 each cage Increased productivity of lake most effective to control waterhyacinth than stocking density 100 and 400 fish/cage.
BIOLOGI REPRODUKSI TUNA MATA BESAR (Thunnus obesus) YANG TERTANGKAP DI SAMUDERA HINDIA
Authors: Faizah Ria , Prisantoso Budi Iskandar 
Published: February 2017

Tujuan penelitian ini adalah untuk mendapatkan informasi mengenai aspek reproduksi ikan tuna mata besar (Thunnus obesus) di perairan Samudera Hindia. Sebanyak 42 contoh gonad dari ikan tuna mata besar yang tertangkap perairan Samudera Hindia antara bulan Maret sampai Oktober 2008 digunakan dalam penelitian ini. Pengamatan meliputi struktur morfologi gonad ikan, perkembangan gonad, diameter telur, dan fekunditas. Hasil penelitian ini menunjukan bahwa ikantuna mata besar yang tertangkap memiliki tingkat kematangan gonad I, II, dan IV. Nilai gonado somatic index rata-rata tuna mata besar semakin meningkat seiring dengan meningkatnya tingkat kematangan gonad. Musim pemijahan untuk tuna mata besar diduga terjadi pada bulan Oktober. Tuna mata besarmemiliki fekunditas antara 8.163.715-10.365.317 butir dan memiliki pola pemijahan berganda. The objective of this research is to study the reproductive biology of big eye tuna (Thunnus obesus) from Indian Ocean. A numbers of 42 gonad samples were taken from fresh individuals captured in the Indian Ocean during period of March until October 2008. The observation comprised of morphological structure of gonad, gonad development, oocytes diameter, and batch fecundity. The results showed that the gonad maturity stages of big eye tuna were ranged from immature (the gonad maturity stage of I and II) to mature (the gonad maturity stage of IV), and the gonado somatic index value increase along with increase of gonad maturity. Spawning season for big eye tuna estimated was in October, range of fecundity were 8.163.715-10.365.317 oocytes, and the spawning type waspartial spawned.
PENGARUH SUBSTRAT DAN KEDALAMAN TERHADAP PERTUMBUHAN SPONS (Callyspongia sp.) DI PERAIRAN JEPARA
Authors: Setyadji Bram , Panggabean Sisco 
Published: February 2017

Potensi spons sebagai bioindikator (biomonitoring dan biomarker), bioremidiasi maupun untuk kebutuhan farmasi dan komersial telah banyak diidentifikasi melalui penelitian-penelitian sebelumnya. Penelitian ini bertujuan untuk memberikan informasi dasar mengenai pengaruh faktor lingkungan (substrat dan kedalaman perairan) terhadap pertumbuhan spons Callyspongia sp. Penelitian ini menggunakan metode eksperimental. Hasil penelitian menunjukan rata-rata laju pertumbuhan panjang spons Callyspongia sp. lebih tinggi pada kedalaman 2 m dibandingkan 1 m pada substrat ban dan jaring. Hubungan antara spons dengan substrat tidak menunjukan perbedaan yang berarti,sedangkan kedalaman diduga merupakan faktor yang lebih berpengaruh terhadap pertumbuhan spons jenis ini. The use of sponge as bioindicator (biomonitoring and biomarker), bioremidiation and pharmaceutical purposes have been widely reported in many studies. However little is known about knowledge of their biological and ecological aspect. The aim of this study was to presents basic information about the influence of substrate and depth on growth of Callyspongia sp. The results showed that the average of length growth of Callyspongia sp. in the water depth 2 m more higher than1 m in both net and tire subtrates here were no differences of growth between net and tire as a substrate, while depth was likely put more influence on the growth of this sponge.
STRATEGI REPRODUKSI IKAN TERBANG (EXOCOETIDAE) DAN KAITANNYA DENGAN FAKTOR OSEANOGRAFI DI PERAIRAN INDONESIA
Authors: Syahailatua Augy , Ali Syamsu Alam , Makatipu Petrus 
Published: February 2017

Ikan terbang (Excoetidae) memiliki strategi reproduksi yang diduga terkait dengan kondisi lingkungan perairan laut, seperti suhu, salinitas, angin, curah hujan, dan radiasi matahari. Penelitian dilakukan untuk 3 jenis ikan terbang (Hirundichthys oxycephalus, Cheilopogon cyanopterus, dan C. Spilopterus) selama tahun 2004 sampai dengan 2007 di perairan Indonesia. Hasil penelitian memperlihatkan bahwa ikan terbang (Excoetidae) memiliki peluang untuk memijah sepanjang tahun, dengan puncak pemijahan agak berbeda antar jenis maupun lokasi. Ada indikasi bahwa kecenderungan strategi pencapaian puncak pemijahan ikan terbang (Excoetidae) sangat dipengaruhi kondisi oseanografi, terutama suhu dan salinitas. Peristiwa upwelling yang secara periodik berlangsung selama musim timur (bulan Juni sampai dengan Agustus) di Laut Flores dan selatan Jawa diperkirakan sebagai faktor pemicu proses pemijahan ikan terbang (Excoetidae), sedangkan pola arus north equatorial di Laut Sulawesi sebagai faktor oseanografi yang mempengaruhi siklus reproduksi ikan terbang (Excoetidae). Pembuktian yang otentik lewat penelitian yang lebih komprehensif sangat diperlukan untuk mengungkapkan hal ini. Informasi ini akan sangat berguna untuk menyusun konsep kebijakan pengelolaan perikanan ikan terbang (Excoetidae) di Indonesia. Reproductive strategy of flyingfish (Exocoetidae) relate to like temperature, salinity, wind, rainfall, and solar radiation. Three species of flyingfish (Hirundichthys oxycephalus, Cheilopogon cyanopterus, and C. Spilopterus) had been observed from 2004 to 2007. The results show that those fishes spawn throughout a year, with the spawning peak differed slightly among species and locations. However, seemingly the spawning peaks associated to the oceanographic conditions, especially temperature and salinity. Reproductive strategic of flyingfish would be generated by decreased temperature. In Flores sea and south of Java, upwelling occurs during the southeast monsoon (June until August), and this event creates low temperature. Whereas in Sulawesi Sea, the decrease of sea surface temperature occurs due to the north equatorial current. A valid evidence from comprehensive study is required to proof the phenomena. This information is valuable to develop a management plan for flyingfish fishery in Indonesia.
Pharmacoepidemiology of Clinically Relevant Hypothyroidism and Hypertension from Sunitinib and Sorafenib
Authors: Walko Christine M. , Aubert Ronald E. , La-Beck Ninh M. , Clore Gosia , Herrera Vivian , Kourlas Helen , Epstein Robert S. , McLeod Howard L. 
Published: February 2017

Abstract

Background
Thyroid dysfunction and hypertension (HTN) have been sporadically reported with sunitinib (SUN) and sorafenib (SOR). Determination of the side effect incidence will enhance monitoring and management recommendations.

Methods
An observational cohort study was performed using deidentified pharmacy claims data from a 3-year period to evaluate patients prescribed SUN, SOR, or capecitabine (CAP; comparison group). The primary outcome was time to first prescription for thyroid replacement or HTN treatment. Hazard ratios (HRs) with 95% confidence intervals (CIs) were estimated by Cox proportional hazards models.

Results
A total of 20,061 patients were eligible for evaluation of thyroid replacement therapy, which was initiated in 11.6% of those receiving SUN (HR, 16.77; 95% CI, 13.54–20.76), 2.6% of those receiving SOR (HR, 3.47; 95% CI, 2.46–4.98), and 1% of those receiving CAP, with median time to initiation of 4 months (range, 1–35 months). A total of 14,468 patients were eligible for evaluation of HTN therapy, which was initiated in 21% of SUN recipients (HR, 4.91; 95% CI, 4.19–5.74), 14% of SOR recipients (HR, 3.25; 95% CI, 2.69–3.91), and 5% of CAP recipients, with median time to initiation of 1 month (range, 1–18 months) for SOR and 2 months (range, 1–25 months) for SUN.

Conclusion
SUN and SOR significantly increased the risk for clinically relevant hypothyroidism; the risk was at least 4 times greater with SUN than with SOR. Patients receiving SUN and SOR had a similar elevated risk for clinically relevant HTN. These data provide robust measures of the incidence and time to onset of these clinically actionable adverse events.
Compassionate Communities and their Role in End-of-Life Care
Authors: Russell Christopher 
Published: February 2017

AbstractDeath is a universal experience that has often been underrepresented in discussion between loved ones and the healthcare system. Given the need for support throughout all aspects of end-of-life care, an emerging paradigm shift shows Compassionate Communities as a new standard for placing responsibility back in the community and promoting respectful and compassionate care. Development of Compassionate Communities promotes quality end-of-life care designed to meet the individualized needs of the dying as well as their caregivers. RésuméLa mort est une expérience universelle qui a souvent été sous-représentée lors de discussions entre les proches d’une personne mourante et le système de soins de santé. Étant donné le besoin de soutien au niveau des diverses facettes des soins de fin de vie, un changement émergent de paradigme démontre que les Communautés bienveillantes sont dorénavant la norme pour confier à nouveau la responsabilité aux communautés, et pour promouvoir des soins respectueux et compatissants. Le développement des Communautés Bienveillantes promeut des soins de fin de vie de qualité, conçus pour répondre aux besoins particuliers des personnes mourantes ainsi que de leurs aides.
3D Printing for 21st Century Medical Learners: Opportunities for Innovative Research and Collaboration
Authors: Wang AiLi , Chung Talia , Anis Hanan , Jalali Alireza 
Published: February 2017

AbstractWith the commercialization of accessible 3D printers, using 3D printing for creation of personalized medical interventions has become a rapidly expanding area of research. In keeping with these developments, the Faculty of Medicine at the University of Ottawa has purchased 3D printers (Makerbot Replicator 2X and Ultimaker 2 Extended +) and launched a collaboration with Makerspace and the Health Sciences Library to investigate local opportunities to incorporate 3D printing into education, simulations and research. This article aims to summarize some of the recent developments in 3D printing and introduce readers to how one could use 3D printing for personalized medicine. RésuméAvec la venue de la commercialisation d’imprimantes 3D accessibles, l’emploi de l’impression 3D pour la création d’interventions médicales personnalisées est un domaine de recherche en développement rapide. Afin de rester à jour avec ces développements, la Faculté de Médecine de l’Université d’Ottawa s’est procuré des imprimantes 3D (Makerbot Replicator 2X et Ultimaker 2 Extended +) et a entamé une collaboration avec Makerspace et la Bibliothèque des Sciences de la Santé, pour examiner des opportunités locales visant à incorporer l’impression 3D à l’éducation, aux simulations et à la recherche. Cet article vise à résumer certains des développe- ments récents en impression 3D et à présenter aux lecteurs la manière dont celle-ci peut être utilisée pour la médecine personnalisée.
Hepatoprotective effect of aqueous extract of Melothria perpusilla against carbon tetrachloride induced liver injury in albino rats
Authors: Yengkhom Nokul S. , Gunindro Ngangom , Kholi Sania M. , Moirangthem Rakesh S. , Rajkumari Bharati D. 
Published: February 2017

Background: In absence of reliable hepatoprotective drug in modern medicine, the traditional herbal medicines have been emphasized. Present study was designed to assess hepatoprotective effect of aqueous extract of Melothria perpusilla (AEMP) against carbon tetrachloride (CCl4) induced liver injury.Methods: Five groups of animals with 6 rats in each were treated for 7 days. Group I received 1% gum acacia in distilled water (1 ml/200 g p.o.) daily. Group II, III, IV and V received CCl4 in liquid paraffin (1 ml/kg s.c.) on day 2, 4 and 6. Group III, IV and V were treated respectively with silymarin (100 mg/kg p.o.), AEMP- 200 and 400 mg/kg p.o. daily. On day 8, liver injury was assessed by measuring serum ALT, AST, ALP and bilirubin.Results: ALT, AST, ALP and bilirubin were significantly reduced in groups receiving both CCl4 and AEMP when compared with CCl4 treated group.Conclusions: AEMP produced hepatoprotective effect against CCl4 induced liver injury.
Remote Usability Testing in Portal Web Perpustakaan Nasional Republik Indonesia.
Authors: Zuntriana Ari 
Published: February 2017

Portal Web Perpustakaan Nasional Republik Indonesia(PNRI) or Indonesian National Library Web Portal is one of the best resources that support education in Indonesia. With the large collection of librarians, PNRI can reach millions of librarian with various education background and area. To ensure its sustainability, we need to conduct research to know how good is the usability this web portal to the remote user. One of the way is using web usability testing. By using this test, PNRI will get the information about what is needed to be fixed and for the next step it can be used as recommendation in redesigning of the portal. PNRI web portal test will be held using remote usability test method. The research is conducted by combining inquiry with formal usability test, like giving a task to the participant. The sampling method used is random sampling by using 32 participant. Data gathering technique used is using online questionnaire. The research result shows that: (1) most of the participant get difficulties in finding information about service schedule; (2) most of the participant dissatisfied in interface design and arrangement in the homepage of PNRI portal. This research is intended as the starting research. It needs the next research to deepen and complete the information and research findings, especially about portal efficiency.
Digital Preservation of Photo Journalism (Case Study of the Kompas Daily)
Authors: Rahmawati Yuli 
Published: February 2017

Newspaper provides many information from politics, economics, cultures, and sports for society. Newspaper reports important events in the world. Besides the news, there also some pictures portraying those events. So readers will easilly to see what happen visually. According to the journalistic concept, photos has comply as a reference source. Kompas daily, firstly published on 1965, and published many historical photos both paper and digital format. The digitize process is done by kompas information center, through scanning, indexing, and syncronizing. Two most important issues are standardization of metadata and integrated retrieval systems. Standarization of metadata was design based on publishing standard, IIM and was modified with IPTC news codes. Information retrieval systems was built by inserting information about publication. This system connecting photo creating data, storage systems, and retrieval systems. For kompas daily, the availability if digital object such as photo can trigger the innitiatives of re-publishing historical momments in thematical rubrics. Digitize will give benefits for information disemination.
Low-Rheology Thermal Cement Design for Long Lateral Production Casing: Case History from the Duvernay Formation
Authors: Ahmady Afshin , Fyten Glen , Stuber Jason , Suarez Nino , Driller Chris 
Published: February 2017

Abstract
This paper presents the design challenges and improvements made to cementing long lateral wells in the Duvernay formation. Low-rheology thermal cement slurries were designed and successfully pumped in more than 30 production jobs. These new designs were coupled with a lower-modeled pumping pressure at higher flow rates that were previously unattainable with conventional designs.
A long lateral production-casing design was used in the Duvernay formation to maximize hydrocarbon production and net present value (NPV). Generally, the lateral horizontal length of a well is increased to enhance wellbore contact with the reservoir. In many cases, the total depth is over 6,000 m, with a lateral section of approximately 3,000 m. Additionally, the typical wellbore diameter is reduced with the goal of decreasing the well cost and, consequently, the unit development cost (UDC).
Sufficient zonal isolation is essential for production casing. Designing low-rheology, thermal cement blends is complex and must meet all slurry-property requirements from both the regulatory board and those required to achieve a competent zonal isolation. These requirements include: Adequate silica content to prevent thermal retrogression500-psi compressive strength in 48 hoursZero free fluidFluid loss of less than 100 cc/30 minLow sedimentation
This paper discusses the primary design changes that led to the improved cement slurry designs, including: Formation fracturingLoss of circulation during cementing and displacementPoor cement quality owing to channeling caused by low flow ratesFailure to bump the top dart for cemented sleeves
A computational fluid dynamics and finite-element simulator was used to evaluate the impact of conventional and improved designs. Improvements led to two new single-slurry designs. These single-slurry designs replaced the previous two slurry jobs (lead and tail), while maintaining the same, or higher, overall well hydrostatic pressure. The newly developed, field-trialed slurries with two different densities (1,675 or 1,750-kg/m3) and low rheology were designed to control the ECD below an acceptable value (fracture gradient = 21 kPa/m) at effective pump rates during both the placement and displacement of the cement slurries. The cement design also allowed for more cost-effective completions, further increasing the well NPV.