bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vascular Tortuosity May Be Associated With Cervical Artery Dissection
Authors: Kim Bum Joon , Yang Ewha , Kim Na-Young , Kim Mi-Jung , Kang Dong-Wha , Kwon Sun U. , Kim Jong S. 
Published: August 2016

Background and Purpose—
Dissection is an increasingly recognized cause of ischemic stroke, which occurs spontaneously or after trauma, in relatively young patients. We hypothesized that there might be a predisposing factor weakening the vascular wall and that arterial tortuosity might be higher in patients with dissection.

Methods—
We consecutively enrolled cervical artery dissection (CerAD) patients who had undergone magnetic resonance angiography. Age- and sex-matched healthy subjects who underwent magnetic resonance angiography in a routine health examination were used as controls. The tortuosity was measured semiautomatically from the carotid artery and vertebral artery (VA) arteries. Tortuosity index was defined as: [(arc/chord)−1×100] in each arteries. Independent risk factors associated with CerAD were investigated using multivariable analysis. Subgroup analysis according to the dissected artery was performed.

Results—

There were no differences in vascular risk factors between the 75 CerAD patients and the 75 controls. The tortuosity indexes of the contralesional VA (16.3±6.8 versus 12.1±4.5, respectively;
P
<0.001) and carotid artery (8.8±4.0 versus 7.3±2.9, respectively;
P
=0.01) were higher in patients with CerAD compared with those of control subjects. VA tortuosity (odds ratio, 1.175;
P
=0.001) was independently associated with the presence of CerAD. In subgroup analysis, VA tortuosity was significantly higher in 57 patients with VA dissection than in controls (
P
<0.001), and carotid artery tortuosity was marginally higher in 18 patients with carotid artery dissection (
P
=0.05).

Conclusions—
CerAD is associated with tortuous cervical arteries, which may implicate weakened cervical vascular structure in these patients.
Higher Risk of Ischemic Events in Secondary Prevention for Patients With Persistent Than Those With Paroxysmal Atrial Fibrillation
Authors: Koga Masatoshi , Yoshimura Sohei , Hasegawa Yasuhiro , Shibuya Satoshi , Ito Yasuhiro , Matsuoka Hideki , Takamatsu Kazuhiro , Nishiyama Kazutoshi , Todo Kenichi , Kimura Kazumi , Furui Eisuke , Terasaki Tadashi , Shiokawa Yoshiaki , Kamiyama Kenji , Takizawa Shunya , Okuda Satoshi , Okada Yasushi , Kameda Tomoaki , Nagakane Yoshinari , Yagita Yoshiki , Kario Kazuomi , Shiozawa Masayuki , Sato Shoichiro , Yamagami Hiroshi , Arihiro Shoji , Toyoda Kazunori ,   for the SAMURAI Study Investigators
Published: August 2016

Background and Purpose—
The discrimination between paroxysmal and sustained (persistent or permanent) atrial fibrillation (AF) has not been considered in the approach to secondary stroke prevention. We aimed to assess the differences in clinical outcomes between mostly anticoagulated patients with sustained and paroxysmal AF who had previous ischemic stroke or transient ischemic attack.

Methods—
Using data from 1192 nonvalvular AF patients with acute ischemic stroke or transient ischemic attack who were registered in the SAMURAI-NVAF study (Stroke Management With Urgent Risk-Factor Assessment and Improvement-Nonvalvular AF; a prospective, multicenter, observational study), we divided patients into those with paroxysmal AF and those with sustained AF. We compared clinical outcomes between the 2 groups.

Results—

The median follow-up period was 1.8 (interquartile range, 0.93–2.0) years. Of the 1192 patients, 758 (336 women; 77.9±9.9 years old) and 434 (191 women; 77.3±10.0 years old) were assigned to the sustained AF group and paroxysmal AF groups, respectively. After adjusting for sex, age, previous anticoagulation, and initial National Institutes of Health Stroke Scale score, sustained AF was negatively associated with 3-month independence (multivariable-adjusted odds ratio, 0.61; 95% confidence interval, 0.43–0.87;
P
=0.006). The annual rate of stroke or systemic embolism was 8.3 and 4.6 per 100 person-years, respectively (multivariable-adjusted hazard ratio, 1.95; 95% confidence interval, 1.26–3.14) and that of major bleeding events was 3.4 and 3.1, respectively (hazard ratio, 1.13; 95% confidence interval, 0.63–2.08).

Conclusions—
Among patients with previous ischemic stroke or transient ischemic attack, those with sustained AF had a higher risk of stroke or systemic embolism compared with those with paroxysmal AF.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT01581502.
La bibliothèque de Mustafa Sıdkı : contribution à l’étude d’une collection de manuscrits au xviiie siècle
Authors: Bonmariage Cécile 
Published: August 2016

The reconstitution of the collection of manuscripts gathered by the 18th century mathematician Mustafa Sıdkı (Muṣṭafā Ṣidqī, d. 1183/1769) has raised interest beyond the milieu of historians of sciences. Building on the findings made by earlier scholars, and adding a number of volumes not yet identified, the article provides an inventory of some ninety manuscripts that were once in the possession of Sıdkı. This inventory shows that Sıdkı’s interests go far beyond sciences and mathematics, and that manuscripts that belonged to his collection found their way to more libraries than previously known.
Cet article entend contribuer à la reconstitution de la bibliothèque de Mustafa Sıdkı (Muṣṭafā Ṣidqī), un mathématicien ottoman du xviiie siècle, mort à Üsküdar en 1183/1769. Il fait le point sur ce qui est connu aujourd’hui, répertorie les manuscrits signalés dans différentes publications, et ajoute à la liste ainsi constituée une quarantaine de manuscrits, qui montrent que les livres ayant appartenu à Sıdkı ont abouti dans d’autres bibliothèques encore que celles repérées jusqu’ici. L’inventaire ainsi constitué, qui regroupe près d’une centaine de volumes, témoigne du large champ des intérêts du collectionneur.
This article is in French.
Marsdenia calichicola (Apocynaceae), a narrow endemic, endangered new species from the Mexican Yucatan Peninsula
Authors: CARNEVALI GERMÁN , TREJO-TORRES JORGE CARLOS , JUÁREZ-JAIMES VERÓNICA , DUNO RODRIGO , TAPIA-MUÑOZ JOSÉ LUIS , RAMÍREZ-MORILLO IVÓN M. , CETZAL-IX WILLIAM 
Published: August 2016

Marsdenia (Apocynaceae: Asclepiadoideae, Marsdeniae) is represented by five species in the Mexican Yucatan Peninsula (vs. seven in the whole of the province), one of which is herein proposed as new to science. The new species, Mardenia calichicola Carnevali & Juárez-Jaimes, is only known from a narrow strip of sub-xerophytic forests over calcareous, rocky soils along the northwestern edge in the Yucatán state of Mexico. Marsdenia calichicola is morphologically similar and likely related to M. gallardoae and M. trivirgulata. Among other characters, it differs from Marsdenia gallardoae by the presence of a corona composed of cushion-like calli (corolla lacking calli in M. gallardoae) whereas M. trivirgulata has a glabrous or glabrescent corolla (vs. pubescent in M. calichicola); additional characters are herein discussed. We provide pertinent iconography to aid in the identification of the new species plus a key to diagnose the three species in the M. trivirgulata complex. The conservation status of the new taxon is assessed against the IUCN criteria as CR. A distribution map and a key to the species of Marsdenia from the Yucatan Peninsula Biotic Province are presented.
Relationships among moral distress, sense of coherence, and job satisfaction
Authors: Ando Michiyo , Kawano Masashi 
Published: August 2016

Background: Since moral distress affects psychological aspects of psychiatric nurses, it is an important theme. Previous studies showed relationships between moral distress and job satisfaction; however, there are few studies which investigate relationships between moral distress and other effective variables and then we highlighted relationships among these variables. Objective: This study aimed to (1) examine relationships among moral distress, sense of coherence, mental health, and job satisfaction and (2) clarify the most predictive variable to job satisfaction. Research design: This study is a cross-sectional study. Participants were 130 psychiatric nurses in a hospital in Japan. They completed the Moral Distress Scale for Psychiatric nurses (Unethical conduct, Low staffing, and Acquiescence to patients’ rights violations), the sense of coherence scale (Comprehensibility, Manageability, and Meaning), the General Health Questionnaire, and the Job Satisfaction scale. Ethical consideration: This study was approved by the ethical board of St Mary’s College. Nurses participated voluntarily and were anonymous. Results: Results showed that subscales of the Moral Distress Scale for Psychiatric nurses negatively correlated to the sense of coherence and the Job Satisfaction. A multiple regression analysis showed that “Acquiescence to patients’ rights violations” of the Moral Distress Scale for Psychiatric nurses and “Meaning” of the sense of coherence influenced the Job Satisfaction much more than other variables. These two variables were correlated to job satisfaction scale, and other variables without them did not significantly correlate to job satisfaction scale. Discussion: These results suggest that moral distress negatively related to sense of coherence and job satisfaction, a subscale of the Moral Distress Scale for Psychiatric nurses and that of the sense of coherence affected the job satisfaction the most. Conclusion: Decreasing of acquiescence to patients’ rights violations and finding meaning in nursing may improve job satisfaction.
Clinical Adaptation of the “Tibiofibular Line” for Intraoperative Evaluation of Open Syndesmosis Reduction Accuracy
Authors: Reb Christopher W. , Hyer Christopher F. , Collins Christy L. , Fidler Corey M. , Watson B. Collier , Berlet Gregory C. 
Published: August 2016

Background: The “tibiofibular line” is a new axial computed tomography parameter for assessing syndesmosis reduction, which references the flat anterolateral surface of the fibula and anterolateral tibial tubercle. These same bony landmarks are easily visualized via a lateral approach to the fibula. This cadaveric study assessed the practical aspects of measuring the tibiofibular line intraoperatively. Methods: Three observers simulated the tibiofibular line using operative rulers in 3 measurement series utilizing 10 cadaveric specimens: intact syndesmosis, syndesmosis reduction, and fixation after application of lateral plate and screws to the fibula, and post syndesmosis reduction and fixation without plate and screws. Results: The majority (78%) of clinical tibiofibular line measurements were within the “normal” range (0-2 mm). However, there was a general trend toward malreduction (>2 mm) across measurement series. Intraobserver variability ranged from poor to excellent (intraclass correlation range, 0.12-0.85, Fleiss kappa range, 0.19-0.40) and interobserver reliability was only generally in the fair range (intraclass correlation range, 0.49-0.61; Fleiss kappa range, 0.19-0.40). Conclusion: Taken as a whole, these findings found that the technique was feasible but clearly indicated that further refinement of this protocol, including the use of computed tomography, would be needed to determine if better control of confounding variables would reveal better observer reliability. Clinical Relevance: The CT-based TFL technique for syndesmosis reduction assessment could not reliably be translated into an intraoperative open technique because of the confounding effects of subjectivity and operator error.
The Role of Fluid Dynamics in Distributing Ankle Stresses in Anatomic and Injured States
Authors: Hamid Kamran S. , Scott Aaron T. , Nwachukwu Benedict U. , Danelson Kerry A. 
Published: August 2016

Background: In 1976, Ramsey and Hamilton published a landmark cadaveric study demonstrating a dramatic 42% decrease in tibiotalar contact area with only 1 mm of lateral talar shift. An increase in maximum principal stress of at least 72% is predicted based on these findings though the delayed development of arthritis in minimally misaligned ankles does not appear to be commensurate with the results found in dry cadaveric models. We hypothesized that synovial fluid could be a previously unrecognized factor that contributes significantly to stress distribution in the tibiotalar joint in anatomic and injured states. Methods: As it is not possible to directly measure contact stresses with and without fluid in a cadaveric model, finite element analysis (FEA) was employed for this study. FEA is a modeling technique used to calculate stresses in complex geometric structures by dividing them into small, simple components called elements. Four test configurations were investigated using a finite element model (FEM): baseline ankle alignment, 1 mm laterally translated talus and fibula, and the previous 2 bone orientations with fluid added. The FEM selected for this study was the Global Human Body Models Consortium–owned GHBMC model, M50 version 4.2, a model of an average-sized male (distributed by Elemance, LLC, Winston-Salem, NC). The ankle was loaded at the proximal tibia with a distributed load equal to the GHBMC body weight, and the maximum principal stress was computed. Results: All numerical simulations were stable and completed with no errors. In the baseline anatomic configuration, the addition of fluid between the tibia, fibula, and talus reduced the maximum principal stress computed in the distal tibia at maximum load from 31.3 N/mm2 to 11.5 N/mm2. Following 1 mm lateral translation of the talus and fibula, there was a modest 30% increase in the maximum stress in fluid cases. Qualitatively, translation created less high stress locations on the tibial plafond when fluid was incorporated into the model. Conclusions: The findings in this study demonstrate a meaningful role for synovial fluid in distributing stresses within the ankle that has not been considered in historical dry cadaveric studies. The increase in maximum stress predicted by simulation of an ankle with fluid was less than half that projected by cadaveric data, indicating a protective effect of fluid in the injured state. The trends demonstrated by these simulations suggest that bony alignment and fluid in the ankle joint change loading patterns on the tibia and should be accounted for in future experiments. Clinical Relevance: Synovial fluid may play a protective role in ankle injuries, thus delaying the onset of arthritis. Reactive joint effusions may also function to additionally redistribute stresses with higher volumes of viscous fluid.
Chunk use and development in advanced Chinese L2 learners of English
Authors: Hou Junping , Loerts Hanneke , Verspoor Marjolijn H. 
Published: August 2016

The use of ‘chunks’ is not only a common and characteristic feature of first language use, but may also be a distinguishing factor between less and more proficient second language users. The present study aimed at investigating potential correlations between chunk use and holistically rated proficiency scores and development over time in advanced Chinese learners of English as a second language (L2) over the course of 18 months of English classes. Neither holistically rated proficiency scores nor common complexity measures had shown any progress in these learners, but a few lexically based measures did. Therefore, the development of chunks in these learners was examined as chunks are mostly lexical in nature and might show more subtle progress over time. The use of chunks was examined in the first and last two texts of the learners and, in line with previous research, it was found that more proficient writers use relatively more chunks, specifically collocations. Chunk coverage, the total number of chunk words divided by the total number of words, also correlated with some holistic proficiency scores, and increased significantly over time. Average chunk length did not show any correlation with proficiency scores nor did it increase over time. Increased proficiency in written texts is thus specifically related to the use of more chunks. This study shows that development in advanced Chinese L2 learners of English appears to be subtle, which might be due to the fact that at this advanced level mainly lexical changes take place. Future research into development over time in advanced learners may thus have to zoom in on lexical measures especially. Implications of this study point to the importance of promoting the use of target language chunks to advanced learners of English.
Analysis of endovascular treatment of ruptured aneurysms of the middle cerebral artery compared to other anatomical locations
Authors: Murias Quintana Eduardo , Vega Valdés Pedro , Morales Deza Edison , Gil Garcia Alberto , Cuellar Hugo , Costilla García Serafín , Cadenas Rodríguez María , Delgado Montserrat Gonzalez , Peña Suárez Jorge , Santamarta Liébana Elena , López-García Antonio 
Published: August 2016

Objective The objective of this article is to compare the results of endovascular treatment of ruptured middle cerebral artery (MCA) aneurysms with ruptured aneurysms of other anatomic locations. Methods Fifty consecutive ruptured aneurysms of the MCA and 209 aneurysms at other anatomical locations were selected retrospectively. We compared epidemiological, clinical and radiological variables, prognosis and complications. Results The MCA aneurysms had a greater size and a poor dome/neck ratio. There were no significant differences in endovascular technique complications, occlusion rate or rebleeding between the two groups ( p > 0.1). There were no significant differences in the mortality and number of dependent patients after one month. Conclusion The endovascular treatment of ruptured MCA aneurysms without hematoma is as safe and effective as other aneurysm localizations. Complication rates, occlusion rates and rebleeding of ruptured MCA aneurysms are comparable to other locations.
Reliability of dual- vs single-volume reconstruction of three-dimensional digital subtraction angiography for follow-up evaluation of endovascularly treated intracranial aneurysms
Authors: Adeeb Nimer , Griessenauer Christoph J , Patel Apar S , Moore Justin , Dolati-Ardejani Parviz , Gupta Raghav , Motiei-Langroudi Rouzbeh , Ogilvy Christopher S , Thomas Ajith J 
Published: August 2016

Introduction Single-volume reconstruction of three-dimensional (3D) digital subtraction angiography (DSA) can be effectively used for aneurysm assessment and planning of endovascular embolization. Unfortunately, post-embolization follow-up angiographic images can be obscured by artifact. The dual-volume reconstruction technique was developed in order to reduce artifact and enhance the visualization of the aneurysm, the parent vessel and side branches, and endovascular devices. The purpose of this study was to compare the reliability of dual- vs single-volume reconstruction of 3D DSA in evaluation of follow-up images after endovascular embolization of intracranial aneurysms. Method Four cerebrovascular neurosurgeons independently and blindly reviewed 20 randomly selected dual-and single-volume reconstructions of 3D DSAs demonstrating cerebral aneurysms treated with primary coil embolization, stent-assisted coil embolization, or Pipeline embolization. Five images were repeated for each modality (single and dual volume) in order to assess intra-rater reliability. The intraclass correlation coefficient was calculated as a measure of the overall inter-rater agreement. Cohen’s kappa value was used to assess repeat measurement consistency for each rater. Results Overall inter-rater agreement using dual- and single-volume reconstruction was 0.81 and 0.75, respectively. Dual-volume reconstruction resulted in superior agreement in assessing location, occlusion status, position of aneurysm recanalization or residual, status of nearby branches, presence of coil migration and presence of intravascular devices (stent or Pipeline). Conclusion Three-dimensional reconstruction is an important complementary imaging technique in evaluating the angioarchitecture of aneurysms and recanalization after endovascular embolization. Dual-volume reconstruction imaging was associated with superior inter- and intra-rater reliability.
Geometrical variations in white and gray matter affect the biomechanics of spinal cord injuries more than the arachnoid space
Authors: Fradet Léo , Arnoux Pierre-Jean , Callot Virginie , Petit Yvan 
Published: August 2016

Traumatic spinal cord contusions lead to loss of quality of life, but their pathomechanisms are not fully understood. Previous studies have underlined the contribution of the cerebrospinal fluid in spinal cord protection. However, it remains unclear how important the contribution of the cerebrospinal fluid is relative to other factors such as the white/gray matter ratio. A finite element model of the spinal cord and surrounding morphologic features was used to investigate the spinal cord contusion mechanisms, considering subarachnoid space and white/gray matter ratio. Two vertebral segments (T6 and L1) were impacted transversely at 4.5 m s−1, which demonstrated three major results: While the presence of cerebrospinal fluid plays a significant contributory role in spinal cord protection (compression percentage decreased by up to 19%), the arachnoid space variation along the spine appears to have a limited (3% compression decrease) impact. Differences in the white and gray matter geometries from lumbar to thoracic spine levels decrease spinal cord compression by up to 14% at the thoracic level. Stress distribution in the sagittal spinal cord section was consistent with central cord syndrome, and local stress concentration on the anterior part of the spinal cord being highly reduced by the presence of cerebrospinal fluid. The use of a refined spinal cord finite element method showed that all the geometrical parameters are involved in the spinal cord contusion mechanisms. Hence, spinal cord injury criteria must be considered at each vertebral level.
Visual aid tool to improve decision making in acute stroke care
Authors: Saposnik Gustavo , Goyal Mayank , Majoie Charles , Dippel Diederik , Roos Yvo , Demchuk Andrew , Menon Bijoy , Mitchell Peter , Campbell Bruce , Dávalos Antoni , Jovin Tudor , Hill Michael D ,   for the HERMES collaborators and the Stroke Outcomes Research working group (SORCan)
Published: August 2016

Background Acute stroke care represents a challenge for decision makers. Recent randomized trials showed the benefits of endovascular therapy. Our goal was to provide a visual aid tool to guide clinicians in the decision process of endovascular intervention in patients with acute ischemic stroke. Methods We created visual plots (Cates’ plots; www.nntonline.net ) representing benefits of standard of care vs. endovascular thrombectomy from the pooled analysis of five RCTs using stent retrievers. These plots represent the following clinically relevant outcomes (1) functionally independent state (modified Rankin scale (mRS) 0 to 2 at 90 days) (2) excellent recovery (mRS 0–1) at 90 days, (3) NIHSS 0–2 (4) early neurological recovery, and (5) revascularization at 24 h. Subgroups visually represented include time to treatment and baseline stroke severity strata. Results Overall, 1287 patients (634 assigned to endovascular thrombectomy, 653 assigned to control were included to create the visual plots. Cates’ visual plots revealed that for every 100 patients with acute ischemic stroke and large vessel occlusion, 27 would achieve independence at 90 days (mRS 0–2) in the control group compared to 49 (95% CI 43–56) in the intervention group. Similarly, 21 patients would achieve early neurological recovery at 24 h compared to 54 (95% CI 45–63) out of 100 for the intervention group. Conclusion Cates’ plots may assist clinicians and patients to visualize and compare potential outcomes after an acute ischemic stroke. Our results suggest that for every 100 treated individuals with an acute ischemic stroke and a large vessel occlusion, endovascular thrombectomy would provide 22 additional patients reaching independency at three months and 33 more patients achieving ENR compared to controls.