bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Long-Term Determinants and Attitudes Toward Smartphone-Based Commercial Health Care Applications Among Patients With Cancer
Authors: Tak Yae Won , Park Ye-Eun , Baek Seunghee , Lee Jong Won , Chung Seockhoon , Lee Yura 
Published: October 2024

PURPOSE
Our study explores how attitudes of patients with cancer toward smartphone-based commercial health care apps affect their use and identifies the influencing factors.

MATERIALS AND METHODS
Of the 960 patients with cancer who participated in a randomized controlled trial for a smartphone-based commercial health care app, only 264 participants, who completed a survey on app usage experiences conducted between May and August 2022, were included in this study. Participants were categorized into three groups: Positive Persistence (PP), Negative Nonpersistence (NN), and Neutral (NE) on the basis of their attitude and willingness to use smartphone-based commercial health care apps. The Health-Related Quality of Life (QOL) Instrument (8 Items), European QOL (5 Dimensions; 5 Levels), The Human Interaction and Motivation questionnaire, and open-ended questionnaires were used to examine factors potentially influencing extended utilization of digital interventions.

RESULTS

Despite demographic similarities among the three groups, only the PP and NE groups showed similar app usage compared with the NN group. The combined group (positive persistence and neutral) exhibited significant improvement in depression (
P
= .02), anxiety (
P
= .03), and visual analog scale scores (
P
= .02) compared with the NN group. In addition, patient interaction (
P
< .01) and the presence of a chatbot/information feature on the app (
P
< .01) demonstrated a significant difference across the three groups, with the most favorable response observed among the PP group. Patients were primarily motivated to use the app owing to its health management functions, while the personal challenges they encountered during app usage acted as deterrents.

CONCLUSION
These findings suggest that maintaining a non-negative attitude toward smartphone-based commercial health care apps could lead to an improvement in psychological distress. In addition, the social aspect of apps could contribute to extending patient's utilization of digital interventions.
Pulmonary-Renal Syndrome in the Elderly: Immunosuppressive Treatment – Case Report
Authors: Żerek Marta , Sitarek Gracjan , Płonka Wojciech , Chruścicki Damian , Bednarczyk Paulina , Pelc Marcin 
Published: October 2024

Pulmonary-renal syndrome is called alveolar hemorrhage accompanied by glomerulonephritis. The above condition can occur as a manifestation of ANCA-associated granulomatosis with vasculitis. The course of the disease varies from mild, limited inflammation to rapid progression with multi-organ changes that can be life-threatening. The mainstay of therapy is immunosuppression - both in the acute phase of the disease and after clinical improvement. Unfortunately, common causes of death in addition to complications of the disease include side effects of immunosuppressive treatment.
A 72-year-old man is transferred to the Nephrology Unit for acute kidney injury of unclear etiology. On the basis of clinical examination, laboratory and imaging studies, a diagnosis of systemic small vessel inflammation with c-ANCA occupying the kidneys, lungs and intestines was made. Due to acute respiratory failure, the patient was transferred to the ICU, where renal replacement therapy, plasmapheresis, steroid pulses and cyclophosphamide were administered. After clinical improvement, it was decided to continue cyclophosphamide therapy and monitor blood IgG levels. Unfortunately, 4 months later, the patient died of multiple organ failure caused by septic shock of bacterial etiology.
In the described case, age and comorbidities were the biggest risk factors for infectious complications of immunosuppression. The population is aging, so it is necessary to analyze the current standards of immunosuppressive treatment to improve the prognosis of the elderly.
Runners injuries - main types of injuries of the musculoskeletal system of the lower limb and their treatment and prevention
Authors: Głąbień Marta , Miłkowski Paweł , Rajewska Aleksandra , Długosz Joanna , Rajewski Jędrzej , Łoś Agnieszka Jolanta , Drużyńska Justyna , Ragan Dagmara , Bara Maciej , Staszczak Paweł 
Published: October 2024

Introduction and purposeRunning is currently one of the most popular physical activities practiced by people around the world, and the number of runners has been growing significantly for many years. The incidence of running-related lower limb injuries in runners ranges between 19.4% and 79.3% [1].The paper presents research results on the main types of injuries of the musculoskeletal system of the lower limb in runners, their risk factors, methods of treatment and prevention. The results indicate a significant relationship between regular training and the occurrence of injuries, and also emphasize the importance of prevention through rest, appropriate running technique and the selection of footwear. The work provides practical tips for runners and coaches that can help reduce the risk of injuries and improve the quality of training.
Materials and methods
The review was conducted by searching PubMed and other scientific databases focusing on currently available publications. The literature available in the PubMed database was reviewed using the following keywords: “running”, “running injuries”, “tendinopathy”, "running related injuries”, “running biomechanics”, “musculoskeletal injuries”. The analysis of 38 articles published between 2014-2024 was used to write the paper.
Conclusions
Running has many health benefits, but unfortunately it can also have a negative effect. The development of medical literature regarding appropriate prevention, knowledge of risk factors and treatment methods improves the prognosis of injuries in runners. Evolving diagnostic imaging, body monitoring, prevention, and adequate rest between activities are essential to long-term success in preventing running-related injuries.
Median and quantile conditional copulas
Authors: Gijbels Irène , Matterne Margot 
Published: October 2024

Abstract
This article studies the conditional dependency between random variables, conditionally upon a covariate (vector). The conditional copula fully characterizes this conditional dependency. A way to summarize this dependence structure taking into account the impact of the covariate is via the average conditional copula, which under fairly general conditions coincides with the partial copula. A mean is just one way to summarize this conditional dependence behaviour. In this article, we introduce the notions of median conditional copula and more generally quantile conditional copula. We investigate the existence of these concepts and establish explicit expressions for calculating them. Examples are given to illustrate the concepts, and the practical use of them is demonstrated in real data examples.
Smart mathematically filtered UV spectroscopic methods for quality assurance of rosuvastatin and valsartan from formulation
Authors: Attimarad Mahesh , Ahmed Amel Y. , Nair Anroop B. , Venugopala Katharigatta Narayanaswamy , Jacob Shery 
Published: October 2024

Abstract
Valsartan and rosuvastatin together in a binary form have been utilized to reduce hypertension and hyperlipidemia to control cardiovascular complications. This study depicts the simple three mathematically manipulated UV spectroscopic techniques for the estimation of rosuvastatin and valsartan in the formulation. The first method is simple UV absorption at 310 nm by RST and the first derivatization method for VTN. Determining the magnitude difference of a ratio spectrum at two identified wavelengths is the second approach, and determination of the magnitude of the first derivatives of the ratio spectra of RST and VTN constitute the third technique. The selection of wavelengths, divisor concentrations, and peak amplitudes were optimized and validated. The straight line was constructed in the range of 1–30 and 2–25 µg/ml for RST and VST by the normal and first derivatization method. By using the magnitude difference and magnitude of first derivative ratio spectra approaches, the concentrations of 1–12 and 2–25 µg/ml for RST and VTN, respectively, displayed a straight line. The limit of quantification was less than 1 µg/ml for RST and less than 2 µg/ml for VTN. It was eventually found that the accuracy, expressed as a percentage recovery, ranged between 98.94 and 99.55% for RST and 100.36 and 101.08% for VTN. The % RSD did not exceed 1.82 and 1.91 for RST and VTN, respectively. The three techniques were used to accurately measure RST and VTN in their binary formulations and physically mixed solutions, and the results were statistically compared to the previously published HPLC technique. The outstanding recovery achieved by using the authentic standard addition approach validated the methods’ supplemental accurateness. The Analytical Greenness and Red Green Blue procedures verified the eco-friendliness of the suggested UV spectroscopic approaches, which were also found to be superior to the documented HPLC methods.
Long COVID elevated MMP-9 and release from microglia by SARS-CoV-2 Spike protein
Authors: Kempuraj Duraisamy , Tsilioni Irene , Aenlle Kristina K. , Klimas Nancy G. , Theoharides Theoharis C. 
Published: October 2024

Abstract

Objective
Long COVID is a major health concern because many patients develop chronic neuropsychiatric symptoms, but the precise pathogenesis is unknown. Matrix metalloproteinase-9 (MMP-9) can disrupt neuronal connectivity and be elevated in patients with long COVID.

Methods
In this study, MMP-9 was measured in the serum of long COVID patients and healthy controls, as well as in the supernatant fluid of cultured human microglia cell line stimulated by recombinant severe acute respiratory syndrome coronavirus 2 Spike protein, as well as lipopolysaccharide (LPS) and neurotensin (NT) used as positive controls. MMP-9 was measured by commercial enzyme-linked immunosorbent assay.

Results
MMP-9 was significantly elevated in the serum of long COVID patients compared to healthy controls. Moreover, there was significant release of MMP-9 from a cultured human microglia cell line stimulated by LPS, NT, or Spike protein. We further show that pretreatment with the flavonoids luteolin and tetramethoxyluteolin (methlut) significantly inhibited the release of MMP-9 stimulated by the Spike protein.

Conclusion
MMP-9 from Spike protein-stimulated microglia could contribute to the development of long COVID and may serve as a target for treatment including the use of luteolin.
Evaluation of recognition memory through oculomotorius behavior in Alzheimer disease.
Authors: Beltrán Rojas Judy Costanza , Lara-Díaz María Fernanda , Arias Castro Diana María 
Published: October 2024

INTRODUCTION: The study of ocular movements in patients with Alzheimer disease is an useful tool to evaluate recognition memory.
METHODS: assessment of this specific type of explicit memory in 15 individuals diagnosed with Alzheimer disease and 15 controls. The parameters of ocular fixation were examined using the Eye-Tracking Tobii Tx300 through Pair-wised ranking with the paradigm novel object recognition.
RESULTS: People with Alzheimer disease present difficulties in the recognition of previously presented stimulus when the latency of presentation of the familiarization and the test period is longer than two minutes.
DISCUSSION: The analysis of oculomotorius behavior can simplify the evaluation of recognition memory without appealing to verbal report and the visual paired comparison task. This contributes to the comprehension of the relationship among spatial attention, working memory and episodic memory.
Presence of meaning in life and subjective well-being as mediators of association between sense of community and academic engagement
Authors: Chukwuorji JohnBosco  C. , Agbo Aaron , Ajaero Chukwuedozie K. , Ifeagwazi Chuka  Mike 
Published: October 2024

We examined the associations between sense of community (SoC) and multidimensional academic engagement, including whether meaning in life and subjective well-being mediate the relationships. Participants were Nigerian students who completed the Classroom Sense of Community Inventory–School Form (CSCI-SF), Meaning in Life Questionnaire’s (MLQ) Presence subscale, Brief Adolescent Subjective Well-being in School Scale (BASWSS), and Utrecht Work Engagement Scale – Student Version (UWES-S-9). Data was analysed using Model 6 of Hayes’ regression-based PROCESS module. Results showed that both presence of meaning and subjective well-being mediated the effects of aspects of SoC on vigour, dedication and overall academic engagement. The effects of SoC on absorption was only mediated by subjective wellbeing. Mediation pathways were not significant for the effects of learning SoC on absorption. In all cases, the strongest mediation existed in the paths linking social SoC to academic engagement through subjective wellbeing. Promotion of classroom SoC may facilitate presence of meaning in life and subjective wellbeing thereby enhancing academic engagement
Szkoła dbająca o dobrostan dzieci – ofiar i świadków przemocy domowej
Authors: Czyżewska Monika 
Published: October 2024

Dobrostan i dobro dziecka to terminy pojawiające się w kontekście roli szkoły w zapobieganiu rodzicielskiemu krzywdzeniu dzieci, które dotyczy co najmniej 1/3 populacji dzieci w Polsce. W tekście omówiono przemiany kultury prawnej w obszarze udzielania pomocy dzieciom-ofiarom przemocy oraz angażowanie się szkoły w zespoły interdyscyplinarne. W części empirycznej przedstawiono wyniki dwukrotnych badań jakościowych, w których posłużono się metodą studium przypadku, przeprowadzonych w 6 szkołach podstawowych (Warszawa - Praga Południe), gdzie w latach 90. XX wieku powstały oddolnie prekursorskie zespoły interdyscyplinarne działające na rzecz dzieci-ofiar przemocy. Wyniki badań ukazują mocne i słabe strony wprowadzonego na poziomie krajowym obowiązku zakładania takich zespołów i ich skuteczność w procesie zapobiegania krzywdzeniu dzieci z perspektywy dyrektorów i specjalistów szkolnych.
Wspieranie potencjału psychospołecznego młodzieży na przykładzie projektu me_HeLi-D
Authors: Borzucka-Sitkiewicz Katarzyna , Kowalczewska-Grabowska Katarzyna 
Published: October 2024

W artykule zaprezentowano projekt “Mental Health Literacy and Diversity. Enhancing Mental Health and Resilience through digital Resources for Youth” (me_HeLi-D), który jest realizowany w ramach programu Erasmus+ w partnerstwie międzynarodowym. Projekt jest zorientowany na bezpośrednią poprawę zdrowia psychicznego i budowanie niezbędnych umiejętności w tym zakresie, a także na promowanie świadomości różnorodności wśród uczniów. Jego nadrzędnym celem jest opracowanie opartego na badaniach, ogólnie dostępnego narzędzia cyfrowego, przeznaczonego dla konkretnej grupy docelowej jaką są uczniowie (w wieku od 12 do 15 lat). Narzędzie ma służyć uczniom do wspierania ich zasobów osobistych oraz wzmacniania i szerzenia wiedzy na temat zdrowia psychicznego.
Motywacyjne i emocjonalne determinanty efektywnej nauki czytania we wczesnym dzieciństwie
Authors: Grelowska Wanda , Buchla Małgorzata 
Published: October 2024

Indywidualizacja w procesie dydaktyczno-wychowawczym skłania do podejmowania działań spersonalizowanych. Jednym z węzłowych poczynań edukacyjnych jest nauka czytania. To ponadprogramowe przedsięwzięcie podjęli nauczycieli przedszkoli województwa dolnośląskiego.
Eksperymentalne badania prowadzone w kilkunastu placówkach miały na celu nie tylko ocenę efektywności alternatywnych metod nauki czytania, ale głównie wydobycie czynników motywujących dziecko do nauki oraz określenie znaczenia stanów emocjonalnych, które towarzyszą temu procesowi. Podjęty problem badawczy wyrażono pytaniem o jakość psychologicznych uwarunkowań w nauce czytania. Wyodrębniono motywację jako siłę napędową do nauki oraz emocje, które stanowią odzwierciedlenie stosunku do rzeczywistości. W założeniach hipotetycznych wskazano na istotny wpływ wymienionych czynników na poziom efektywności w nauce czytania. Do realizacji celu badawczego przydatna okazała się metoda obserwacji. Instrumentarium badawcze uzupełniono ankietą skierowaną do rodziców.
Analiza wyników badań pokazuje, że motywacja rodziców i dzieci zwiększa się proporcjonalnie do poziomu efektywności w nauce i sięga 80%. Towarzyszą temu pozytywne emocje, które wyrażają zarówno dzieci, jak też ich rodzice. Czytanie w przedszkolu motywuje do podjęcia kontynuacji w domu, na co wskazuje 78% respondentów. Rodzice domagają się nawet udostępnienia materiałów edukacyjnych, by móc uczyć swoje dziecko w domu. Wskazują też na możliwość zacieśniania więzi emocjonalnej z dzieckiem w czasie wspólnego obcowania z tekstem. Z kolei brak postępów we wczesnym czytaniu przekłada się na zniechęcenie i występowanie emocji o znaku ujemnym.
Warto zatem podejmować działania motywujące do wysiłku. Postuluje się, by uatrakcyjnić przebieg zadań, którym towarzyszy wysiłek i żmudne, wielokrotne powtórzenia. Uruchomienie wewnętrznych mechanizmów motywacyjnych może następować poprzez stworzenie m.in. przyjaznej atmosfery. Sugeruje się też dobór humorystycznych tekstów do czytania, by wywołać klimat radości. Kulminacją podejmowanych przedsięwzięć powinien być motyw działaniowy, który wyraża się w czytaniu z inicjatywy dziecka.
Reasumując, można stwierdzić, że motywowanie dziecka do nauki w atmosferze przyjaźni i radości sprzyja efektywności we wczesnej nauce czytania.
Desde la periferia
Authors: Mariano Juárez Lorenzo , Conde Caballero David 
Published: October 2024

Archives on Food, Culture and Nutrition (AFOCUN) was sponsored by the International Commission on Anthropology of Food and Nutrition (ICAF) with the firm commitment of a small Spanish university – the University of Extremadura – to what can be seen as an affirmation of its counter-current spirit. It is born in some way in the subalternity, located on the periphery of the great centers of knowledge dissemination, alien to the flows of exchange of broad academic capital. And it also did so with the aim of clarifying the category of Open Access (OA), offering researchers a space to disseminate their findings free of charge and without restriction of any kind. This assumption of subalternity as a political ethos also refers to the delimitation of the objects of study that can be addressed in this publication. In the first place, because of a firm commitment to interdisciplinarity, given that the journal is open to publications that address the food issue from different perspectives. But also, because of the firm commitment to offer a space for contexts of subalternity that have not been addressed with due attention.
This issue largely addresses all these foundational ethos of the publication with which it intends to carve out a path. It combines research by authors of recognized prestige in the academic and cultural fields with incipient authors; It caters to different languages, such as English and Spanish, while opening its doors to European, but also Asian and American researchers. But, above all, this second issue of AFOCUN provides a space for multidisciplinary expression and reflection on food and nutrition, addressing classic topics such as indigenous ways of eating with other more innovative ones such as reflection on the "cultural sustainability" of food systems.
Contribution of Spectral and Temporal Cues in Timbre Recognition among Normal-Hearing and Hearing- Impaired People
Authors: Mohammadi Mohammad , Maarefvand Mohammad , Pourbakht Akram 
Published: October 2024

Background and Aim: Timbre perception is a multidimensional feature of music perception and hearing loss may deteriorate timbre and instrument recognition. Deficits in timbre recognition may originate from poor temporal or spectral coding of musical notes subsequent to hearing loss However, it is not well understood which of these features are more dominant in instrument recognition with normal hearing and hearing loss. This study aimed to evaluate the relative importance of temporal and spectral cues instrument recognition in people with and without nearing loss.
Methods: Two groups of adults with normal-hearing and hearing loss were tested with the timbre subtest of the Clinical Assessment of Music Perception (CAMP). Originally, a series of notes is played with eight musical instruments and participants were asked to identify the played instrument among them. In two other conditions, either the rise time or spectral cues of the same notes were masked using a special masking technique. Among eight instruments.
Results: Instrument recognition scores were not significantly different between the original and spectral-manipulated conditions but were lower at the temporal-manipulated condition. The difference between the two groups was significant (p<0.05), where the normal-hearing group recognized the musical instruments significantly better than participants with hearing loss group (p<0.05).
Conclusion: Temporal cues may have greater importance on timbre recognition regardless of hearing status. This suggests that the interventions and assistive devices which are designed to improve timbre recognition for people with hearing loss should prioritize improvement in temporal coding.
Keywords: Timbre recognition; hearing loss; music; musical instrument; temporal; spectral
Navigating New Terrain: Exploring Orientation Programs For New Academic Staff and Their Experience
Authors: Hussin Anealka Aziz , Paridaluddin Noorfarida Filzah Mohd Sobri , Hashim Haida Umiera , Ismail Nur Asyrani Che , Sukri Hanna Insyirah Mohd 
Published: October 2024

Commencing a new job can instigate anxiety, especially for those without prior work experience. The excitement of a fresh employment endeavour may coincide with feelings of discomfort, stemming from unfamiliar expectations. A comprehensive overview and understanding on orientation programs for new staff can play a crucial role in facilitating their adaptation, fostering departmental understanding, fostering colleague connections, and grasping job essentials. This research seeks to assess orientation activities carried out for new academic staff joining the faculty by the management while investigating the orientation program experience of recently onboarded staff members with less than six years of experience in one of the language academies in a public university in the Klang Valley. An interview and survey were conducted and revealed notable areas of concern including employee benefits, performance expectations, departmental and faculty structures, policies and procedures and training development. The findings delineated key areas of concern as a foundational framework to be concentrated by the management during future faculty staff recruitment. This study also highlights the need to develop a tailored orientation kit for new onboarding staff to the faculty.