bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Efficacy and Safety of Potassium-Competitive Acid Blocker-Based Dual, Triple, and Quadruple Regimens for First-Line Helicobacter pylori Infection Treatment: A Systematic Review and Network Meta-Analysis
Authors: Rokkas Theodore , Ekmektzoglou Konstantinos , Niv Yaron , Graham David Y. 
Published: September 2024

INTRODUCTION:
In the last few years, numerous new potassium-competitive acid blocker (P-CAB)-based randomized controlled trials (RCTs) concerning the first-line regimens for Helicobacter pylori infection treatment from various countries have been published. However, no network meta-analysis (NWM) exists, which examines the comparative efficacy and safety of P-CAB-based dual, triple, and quadruple treatments, and, therefore, in this NWM, we examined this matter comparing efficacy and safety of these P-CAB-based regimens.

METHODS:
Databases were searched for identification, screening, eligibility, and inclusion of relevant RCTs. Extracted data were entered into a Bayesian NWM, and the ranking order for each regimen was evaluated by means of the surface under the cumulative ranking area values.

RESULTS:
Twenty-five eligible RCTs were included with 7,605 patients randomized to 6 first-line regimens, i.e. P-CAB dual therapy, P-CAB triple therapy, P-CAB quadruple therapy, PPI dual therapy, PPI triple therapy, and PPI quadruple therapy. The surface under the cumulative ranking area values (%) for these 6 regimens were 92.7, 62.5, 33.9, 75.1, 19.4, and 16.3, respectively. The comparative effectiveness ranking showed that P-CAB dual therapy regimen ranked first for efficacy and last for adverse effects and had the best profile for integrated efficacy-safety.

DISCUSSION:
In this NWM concerning the comparative efficacy and safety of P-CAB-based dual, triple, and quadruple regimens for the first-line H. pylori infection treatment, the overall results showed that P-CAB-based dual treatment ranked first for efficacy with the best-integrated efficacy-safety profile. This is of importance, since the dual regimens overcome the crucial issue of clarithromycin resistance. Consequently, these findings are expected to be useful in helping clinical decision making and future guidelines.
Composite Mesh in Incisional Hernia Repair: Unprecedented Gastric Penetration and Gastrocutaneous Fistula Formation
Authors: Abuassi Mohammad , Joulani Walid , Sammodi Emad , Eftaiha Mohamed , Obed Aiman 
Published: September 2024

ABSTRACT
Hernia repair frequently employs surgical mesh. However, potential complications exist, including mesh migration into adjacent organs, leading to serious outcomes such as enteric fistulas. We report an unprecedented case of composite mesh leading to gastric penetration and subsequent gastrocutaneous fistula formation, identified during endoscopic investigation as a foreign body. A 70-year-old man who underwent right hemicolectomy and incisional hernia repair using composite mesh presented in with symptoms of intestinal obstruction and a small bowel content leak. Following these complications, a small bowel resection was performed, and an ileostomy was created. During an endoscopic investigation, the composite mesh used in the hernia repair during the ileostomy creation was found as a foreign body penetrating the gastric antral area, causing a gastrocutaneous fistula. An exploratory laparotomy was successfully carried out. This case highlights the need to consider mesh-related complications and advocates for research into prevention and management of such adverse outcomes.
Nontyphoidal Salmonella Hepatitis: A Rare Complication of a Common Enteric Infection
Authors: Bierowski Matthew J. , Edirisuriya Chelsea D. , Goldberg Ilana P. , Noverati Nicholas , Johnson Peter , Choudhary Cuckoo , Shivashankar Raina 
Published: September 2024

ABSTRACT
Hepatitis from nontyphoidal Salmonella gastroenteritis is rare, especially in immunocompetent patients. We present the case of a 30-year-old woman who was found to have Salmonella serotype C2 gastroenteritis and elevated liver function tests concerning for concurrent hepatitis. An extensive workup was negative for other etiologies, making Salmonella the likely culprit. The patient was managed with supportive measures as her liver function tests and symptoms were improving before obtaining microbiological data. Since the role of antibiotic therapy in such cases is not well studied, disease severity in accordance with current guidelines should be used to tailor treatment on a case-by-case basis.
MEMPERSIAPKAN KELUARGA SAKINAH
Authors: Supriatna Supriatna 
Published: September 2024

Perkawinan merupakan suatu anugerah Allah agar makhluk hidup bisa mempertahankan keberlangsungan hidupnya. Perkawinan yang ditetapkan Allah adalah lembaga luhur untuk mengatur hubungan antara laki-laki dan perempuan sesuai dengan martabat manusia. Bentuk perkawinan yang disyari'atkan oleh agama Islam telah memberikan jalan yang aman pada naluri seks, memelihara keturunan dengan baik dan menjaga kaum perempuan agar tidak laksana rumput yang bisa dimakan oleh binatang ternak dengan seenaknya. Menurut syari'at Islam, tujuan seseorang melakukan perkawinan di antaranya adalah untuk mewujudkan kehidupan yang sakînah dengan dilandasi mawaddah wa rahmah, yaitu kehidupan yang tentram yang dilandasi cinta (mawaddah) dan kasih sayang (rahmah) di antara suami isteri dan seluruh anggota keluarga.
KEWARISAN ANAK HASIL INCEST
Authors: Fuad Ahmad 
Published: September 2024

Berdasarkan realitas yang ada, perbuatan incest, dengan kata lain hubungan seksual sedarah, sudah semakin merebak. Upaya untuk meminimalisir adanya perilaku incest tersebut, yakni adanya kontrol masyarakat dan penegakan hukum yang tegas sesuai dengan ketentuan syariat terhadap para pelaku incest. Harapannya agar pelaku incest menjadi jera dan dapat menjadi pelajaran bagi masyarakat sekitarnya, supaya lebih berhati-hati dan tidak terjerumus dalam perbuatan tersebut. Bagi setiap insan kamil, khususnya pemuka agama, tokoh masyarakat diharapkan peran yang sangat penting untuk memberikan pengertian dan penjelasan mengenai larangan melakukan hubungan zina, lebih lagi melakukan hubungan seksual yang dilakukan antara anggota keluarga (incest). Bagi masyarakat luas, hendaklah jangan mencaci-maki atau menggunjing bila di antara masyarakat ada anak yang dilahirkan dari perbuatan zina/incest dengan sebutan-sebutan yang merendahkan harga diri anak tersebut, sebab anak tersebut tidaklah salah dilahirkan di dunia ini yang salah adalah perbuatan kedua orang tuanya yang menyebabkan kelahiran anak ini. Anak ini adalah anak yang normal serta memiliki hak hidup yang sama dengan anak lainnya.
HIBAH ORANG TUA KEPADA ANAK SEBAGAI PENGGANTI WARIS (Telaah Hermeneutika Terhadap Pasal 211 Kompilasi Hukum Islam)
Authors: Al Amin M. Nur Kholis 
Published: September 2024

The inheritance of wealth is to be experienced by every Muslim family. Essentially, in Islamic inheritance implemented as heir had died. However, in the lives of the people of Indonesia held a lot going on heritage heir, who in this case the parents to their children will still living with an alternative bussiness “grants”. It has been granted legalization to determined the article 211 KHI, which seemed to give the inheritance of the practice of Islamic ortodoxy hit. Therefore, it is interesting to analyze further what lies behind the preparation and legal substance to the article. This paper seeks to understand the substance and stored legal values in article 211 KHI by using the approach og “legal hermeneutics”. [Proses kewarisan harta kekayaan merupakan hal yang akan dialami setiap keluarga muslim. Pada dasarnya kewarisan dalam Islam dilaksanakan ketika pewaris telah meninggal dunia. Namun, dalam kehidupan masyarakat Indonesia banyak terjadi kewarisan yang dilaksanakan pewaris, yang dalam hal ini orang tua kepada anaknya ketika orang tua masih hidup dengan menggunakan usaha alternatif berupa hibah. Hal ini telah diberikan legalisasi dengan terumuskannya Pasal 211 KHI, yang seakanakan memberikan legalisasi terhadap praktik kewarisan dengan menabrak ortodoksi kewarisan Islam. Oleh karena itu, hal tersebut menarik untuk ditelaah lebih lanjut apa yang melatarbelakangi penyusunan dan substansi hukum pada pasal tersebut. Tulisan ini berusaha untuk memahami substansi dan menakar nilai-nilai hukum yang tersimpan pada Pasal 211 KHI dengan menggunakan pendekatan “hermeneutika hukum”.]
NUSYUZ: ANTARA KEKERASAN FISIK DAN SEKSUAL
Authors: Faizah Nur 
Published: September 2024

Nushuz is a classical conception of law that has been codified as standard the rule of law in the Compilation of Islamic Law (KHI). Some Muslims consider the explanation of the scholars about nushuz is taken for granted, mainly because it was labeled “religion” that is considered sacred and there is no room for change especially criticized. KHI is certainly not free from power, value s, and interests, in particular, of its the patriarchal apparatus of constituent, so women tend to be faced with a wall of injustice, subordination, masculine superiority and imbalance. This is reflected in provisions of nushuz in KHI that apply to the wife only and does not apply to husbands. Terms of nushuz in KHI also justify domestic violence, especially in the case of forced sexual intercourse by a husband against his wife. This article explains that in fact issue of nushuz is for husband and wife. However, the plains of empirical, KHI in explaining provisions of of nushuz apply to the wife only. This is where KHI has been marginalized and dehumanization of women.[Nusyu>z merupakan konsepsi hukum klasik yang telah terkodifikasikan sebagai aturan hukum baku dalam Kompilasi Hukum Islam (KHI). Sebagian umat Islam memandang penjelasan para ulama tentang nusyu>z merupakan hal yang terberi (taken for granted), terutama karena sudah diberi label “ajaran agama” sehingga dipandang sakral dan tidak ada ruang untuk mengkritisinya apalagi mengubahnya. KHI tentu tidak bebas dari kuasa, nilai, dan kepentingan, terutama, dari apparatus pembentuknya yang patriarkis, sehingga perempuan cenderung dihadapkan dengan tembok ketidakadilan, subordinasi, superioritas maskulin, dan ketidakseimbangan (dis-equilibrum). Hal itu tercermin dariketentuan nusyu>z dalam KHI yang hanya diberlakukan terhadap isteri saja dan tidak berlaku bagi suami. Ketentuan nusyu>z dalam KHI juga membenarkan tindakan KDRT, terutama dalam hal pemaksaan hubungan seksual oleh suami terhadap isterinya. Artikel ini memberikan penjelasan bahwa sebenarnya persoalan nusyu>z adalah bagi isteri dan suami. Namun pada dataran empirik, KHI dalam menjelaskan ketentuan nusyu>z hanya berlaku untuk isteri saja. Di sinilah KHI telah memarginalkan dan mendehumanisasi perempuan.]
PANDANGAN TOKOH-TOKOH NAHDLATUL ULAMA (NU) DAERAH ISTIMEWA YOGYAKARTA TERHADAP PUTUSAN MAHKAMAH KONSTITUSI (MK) NO. 46/PUU-VIII/2010 TENTANG STATUS ANAK DI LUAR NIKAH
Authors: Abdillah Kudrat 
Published: September 2024

Status of children in the family will determine the rights and obligations of the parents. Status of children in Islamic law called lineage, and legal validity depends on the relationship between father and mother. Constitutional Court on February 17, 2012, issued Decision No.. 46/PUU-VIII/2010 about the status of a child out of wedlock that states a child out of wedlock have a civil relationship with the biological father to prove it using science and technology. The decision generated much debate, so that authors see interesting things if this phenomenon is discussed with a view of figures of Islamic society organizations, the Nahdlatul Ulama in Yogyakarta Special Region.[Status anak dalam keluarga sangat menentukan hak dan kewajiban dari orang tuanya. Dalam hukum Islam status anak disebut nasab, dan sah tidaknya bergantung pada sah tidaknya hubungan antara bapak dan ibunya. Mahkamah Konstitusi pada tanggal 17 Februari 2012, mengeluarkan Putusan No. 46/PUU-VIII/2010 tentang status anak di luar nikah yang menyatakan anak di luar nikah mempunyai hubungan perdata dengan bapak biologisnya dengan membuktikannya menggunakan ilmu pengetahuan dan teknologi. Putusan tersebut menimbulkan banyak perdebatan, sehingga penyusun melihat ada hal yang menarik jika fenomena ini dibahas dengan pandangan tokoh-tokoh organisasi masyarakat Islam, yaitu Nahdlatul Ulama di Daerah Istimewa Yogyakarta.]
HAK-HAK PEREMPUAN PASCA PERCERAIAN: Nafkah Iddah Talak dalam Hukum Keluarga Muslim Indonesia, Malaysia, dan Yordania
Authors: Hammad Muchammad 
Published: September 2024

Regulations regarding divorce idda living in Muslim Family Law (Indonesia, Malaysia and Jordan) in general there is no difference with that found in conventional jurisprudence. Income levels that can be changed according to price inflation not contained in conventional jurisprudence, were living in Muslim Family Laws can be changed. Regulations regarding the divorce waiting period contained living in Muslim Family Law Malaysia and Jordan still better guarantee the rights of women post-divorce compared with existing regulations in Indonesia. [Peraturan mengenai nafkah iddah talak pada Hukum Keluarga Muslim (Indonesia, Malaysia dan Yordania) secara umum tidak ada perbedaan dengan yang terdapat pada fikih konvensional. Kadar nafkah yang dapat berubah sesuai inflasi harga tidak terdapat dalam fiqih konvensional, sedang dalam Hukum Keluarga Muslim nafkah tersebut dapat berubah. Peraturan mengenai nafkah iddah talak yang terdapat dalam UU Keluarga Muslim Malaysia dan Yordania masih lebih menjamin hakhak perempuan pasca perceraian dibandingkan dengan peraturan yang ada di Indonesia.]
IMPLIKASI PUTUSAN MAHKAMAH KONSTITUSI NOMOR 46/ PUU-VII/2010 TERHADAP HUKUM PERKAWINAN INDONESIA
Authors: Basuki Udiyo 
Published: September 2024

The Constitutional Court has passed a decision in the case of petition reviewing Act No.1 of 1974 on Marriage to The 1945 Constitution. Decision is in principle to measure the constitutionality of the provisions of the Mariege Act governing registration of marriages according to the laws and regulations governing children born outside of the marriage. Through juridical analysis, this paper examines the implications of Constitutional Court Decision No. 46/PUU-VII/2010 against marriage law in Indonesia.[Mahkamah Konstitusi telah menjatuhkan putusan dalam perkara permohonan Pengujian Undang-Undang Nomor 1 Tahun 1974 tentang Perkawinan terhadap Undang-Undang Dasar Negara Republik Indonesia Tahun 1945. Pada prinsipnya putusan mengukur konstitusionalitas ketentuan UU Perkawinan yang mengatur pencatatan perkawinan menurut peraturan perundang-undangan dan ketentuan yang mengatur anak yang lahir di luar perkawinan. Melalui analisis yuridis, tulisan ini mengkaji implikasi Putusan Mahkamah Konstitusi Nomor 46/PUU-VII/2010 terhadap hukum perkawinan di Indonesia.]
BISAKAH LEMBAGA HUKUM ADAT MEMINIMALISIR PERNIKAHAN SIRRI?
Authors: Mujib M. Misbahul 
Published: September 2024

Sirri marriage actually has negative implications on the society. Logically a causation of Sirri marriage is caused by customary law. Unwritten character of customary law which causes all decisions or products, including marriage is not well written. This paper aims to know how the customary law minimize sirri marriage, can the customary law do it. It is realistic of course if then customary law institutions minimize Sirri marriage because one of reasons for the growth of Sirri marriage is customary law. Making customary law institutions as part of the national legal institutions can be used as an alternative to minimize Sirri marriage. The relationship between customary law with national law should be developed in the direction of strengthening the institutions of customary law as part of the national legal institutions. The defining of sirri marriage should be extended to have proof of marriage. Powers noted wedding events should also be extended to customary law institutions not only KUA or civil records only, or at least braided communication between KUA, the civil institutions and customary lawinstitution.[Pernikahan sirri secara nyata mempunyai implikasi negatif di dalam masyarakat. Secara logis perkembangan nikah sirri salah satunya disebabkan oleh hukum adat. Karakter hukum adat yang tidak tertulis menyebabkan semua putusan ataupun produk hukum adat termasuk pernikahan juga tidak tertulis. Tulisan ini bertujuan bagaimana menjadikan hukum adat dapat meminimalisirpernikahan sirri. Adalah realistis tentunya kalau kemudian upaya meminimalisir pernikahan sirri bisa melalui lembaga hukum adat, karena salah satu sebab tumbuhnya pernikahan sirri adalah hukum adat. Menjadikan lembaga hukum adat sebagai bagian dari lembaga hukum nasional bisa dijadikan alternatif untuk meminimalisir pernikahan sirri. Hubungan antara hukum adat dengan hukum nasional harus dikembangkan ke arah penguatan lembaga hukum adat sebagai bagian dari lembaga hukum nasional. Pemaknaaan nikah sirri harus diperluas menjadi nikah yang mempunyai bukti. Wewenang mencatat peristiwa pernikahan harus juga diperluas kepada lembaga hukum adat bukan hanya KUAatau catatan sipil semata, atau setidaknya dijalin komunikasi antara KUA, catatan sipil dengan lembaga hukum adat].
Mild dehydration does not alter acute changes in sweat electrolyte concentrations during exercise
Authors: Baker Lindsay B. , Ozga Michal , Merritt James R. , Alfred Shelby , De Chavez Peter John D. , Hinkley J. Matthew 
Published: September 2024

AbstractThe purpose of this study was to determine the effect of hydration status on the change in sweat sodium (Na+), chloride (Cl−), and potassium (K+) concentrations during exercise‐heat stress. Fifteen subjects (Six female, nine male; 29 ± 9 y; 71 ± 14 kg) completed 90 min of cycling (81% HRmax) in the heat (~33°C, 42% rh) with fluid replacement to maintain euhydration (EUH) or without fluid to dehydrate to 2.4 ± 0.4% body mass loss (DEH). Sweat was collected from the forehead (FH), right scapula (SCAP), and left (LVFA) and right (RVFA) ventral forearms using the absorbent pad technique at the beginning (0–30 min) and end of exercise (60–90 min). Sweat was analyzed for Na+, Cl−, and K+ concentrations using ion chromatography. Data are reported as mean ± SD or median ± IQR. There were no differences (Paired t‐tests or Wilcoxon signed‐rank tests) between EUH and DEH in the change in sweat Na+ (FH: 24.3 ± 21.5 vs. 30.8 ± 22.4 mmol/L; SCAP: 9.7 ± 6.2 vs. 9.6 ± 8.2 mmol/L; LVFA: 7.5 ± 6.0 vs. 5.6 ± 5.9 mmol/L; RVFA: 8.2 ± 8.6 vs. 7.8 ± 5.2 mmol/L), sweat Cl−, or sweat K+ at any site (p = 0.07–0.99). The change in sweat electrolyte concentrations during 90 min of exercise in the heat was not significantly influenced by mild dehydration in recreational to moderately‐trained male and female athletes.
Aristotle’s Perceptual Objectivism
Authors: Arsenault Michael 
Published: September 2024

Abstract
Objectivism about perceptible qualities like colors and sounds is the view that perceptible qualities are ontologically and conceptually independent from perception. We ordinarily think of Aristotle as an objectivist about perceptible qualities – even the arch-objectivist. Yet this consensus has long been threatened by various thorny passages, including especially De anima III.2, 425b26–426a28, which appear to suggest that Aristotle is no objectivist, but a subjectivist. I show that recent attempts to make sense of these passages by appeal to Aristotle’s three-stage distinction between first potentiality, second potentiality/first actuality, and second actuality commit Aristotle to a subjectivism that he cannot consistently endorse. I argue for an alternative that vindicates Aristotle’s objectivism.
A Comparative Study of the L2 Pragmatic Competence of University Students in Hong Kong and the Chinese Mainland: The Contributions of Sociocultural Context and Linguistic Proficiency
Authors: Aubrey Scott , Ellis Rod 
Published: September 2024

Abstract
This study investigates the differences in pragmatic competence between Hong Kong and Chinese mainland university students. Participants included 19 native speakers of English, 115 Chinese mainland students, divided into those who had spent time abroad in an English-speaking country (CM A) and those who had not (CM NA), and 97 Hong Kong students, divided into those from an English-medium secondary school (Hong Kong EMI) and those from a Chinese-medium school (Hong Kong CMI). Linguistic proficiency was measured by a C-test, and pragmatic competence by a Metapragmatic Knowledge Test, an Irony Test and a Monologic Role Play. Group scores were compared using ANCOVAs to control for differences in proficiency. The results point to a continuum of pragmatic competence—EMI > CMI > CM A > CM NA—reflecting the groups’ access to English in real-life contexts. The differences between the Hong Kong groups and the Chinese mainland groups were clearest in those tests measuring processing capacity (i. e., Irony Response Time and the Monologic Role Play). CM A, but not CM NA, performed as well as the Hong Kong groups on measures of metapragmatic awareness. The results are discussed in terms of Bialystok’s (1993) distinction between analyzed representation and control of processing.
Analyzing the impact of transfer learning on explanation accuracy in deep learning-based ECG recognition systems
Authors: Khorsheed May Sadiq , Karim AbdulAmir Abdullah 
Published: September 2024

Abstract
Electrocardiogram (ECG) recognition systems now play a leading role in the early detection of cardiovascular diseases. However, the explanation of judgments made by deep learning models in these systems is prominent for clinical acceptance. This article reveals the effect of transfer learning in ECG recognition systems on decision precision. This article investigated the role of transfer learning in ECG image classification using a customized convolutional neural network (CNN) with and without a VGG16 architecture. The customized CNN model with the VGG16 achieved a good test accuracy of 98.40%. Gradient-weighted class activation mapping (Grad-CAM), for this model, gave the wrong information because it focused on parts of the ECG that were not important for making decisions instead of features necessary for clinical diagnosis, like the P wave, QRS complex, and T wave. A proposed model that only used customized CNN layers and did not use transfer learning performed 99.08% on tests gave correct Grad-CAM explanations and correctly identified the influencing areas of decision-making in the ECG image. Because of these results, it seems that transfer learning might provide good performance metrics, but it might also make things harder to understand, which could make it harder for deep learning models that use ECG recognition to be reliable for diagnosis. This article concludes with a call for careful consideration when using transfer learning in the medical field, as model explanations resulting from such learning may not be appropriate when it comes to domain-specific interpretations.