bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-Term Outcomes Following Hip Fractures in Patients at Least 100 Years Old
Authors: Manoli Arthur , Driesman Adam , Marwin Rebecca A. , Konda Sanjit , Leucht Philipp , Egol Kenneth A. 
Published: July 2017

Background:
The number of hip fractures is rising as life expectancy increases. As such, the number of centenarians sustaining these fractures is also increasing. The purpose of this study was to determine whether patients who are ≥100 years old and sustain a hip fracture fare worse in the hospital than those who are younger.

Methods:
Using a large database, the New York Statewide Planning and Research Cooperative System (SPARCS), we identified patients who were ≥65 years old and had been treated for a hip fracture over a 12-year period. Data on demographics, comorbidities, and treatment were collected. Three cohorts were established: patients who were 65 to 80 years old, 81 to 99 years old, and ≥100 years old (centenarians). Outcome measures included hospital length of stay, estimated total costs, and in-hospital mortality rates.

Results:
A total of 168,087 patients with a hip fracture were identified, and 1,150 (0.7%) of them had sustained the fracture when they were ≥100 years old. Centenarians incurred costs and had lengths of stay that were similar to those of younger patients. Despite the similarities, centenarians were found to have a significantly higher in-hospital mortality rate than the younger populations (7.4% compared with 4.4% for those 81 to 99 years old and 2.6% for those 65 to 80 years old; p < 0.01). Male sex and an increasing number of medical comorbidities were found to predict in-hospital mortality for centenarians sustaining extracapsular hip fractures. No significant predictors of in-hospital mortality were identified for centenarians who sustained femoral neck fractures. An increased time to surgery did not influence the odds of in-hospital mortality.

Conclusions:
Centenarians had increased in-hospital mortality, but the remaining short-term outcomes were comparable with those for the younger cohorts with similar fracture patterns. For this extremely elderly population, time to surgery does not appear to affect short-term mortality rates, suggesting a potential benefit to preoperative optimization.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Protected Time for Research During Orthopaedic Residency Correlates with an Increased Number of Resident Publications
Authors: Williams Benjamin R. , Agel Julie A. , Van Heest Ann E. 
Published: July 2017

Background:
The Accreditation Council for Graduate Medical Education (ACGME) requires orthopaedic residency programs to promote scholarship and research, which manifest differently among programs. We assess the impact of protected research time during orthopaedic residency on the number of resident publications.

Methods:
Rotation schedules and resident names were collected from 125 ACGME-accredited U.S. orthopaedic residency programs. Protected research time was classified as 1 of 3 types: (1) block time, (2) longitudinal time, or (3) no dedicated time. In April 2016, we searched residents in postgraduate year (PGY)-3 to PGY-5 on pubmed.gov to generate all orthopaedic publications with a PubMed identifier published during residency. Each publication’s 2015 Thomson Reuters Journal Citation Reports 5-Year Journal Impact Factor and resident first authorship were noted. The number of PubMed identifiers for each program was summed and was divided by the number of residents in PGY-3 to PGY-5, giving a mean number of publications per resident. The relationship between output and program research time was compared using t tests and analysis of variance (ANOVA).

Results:
A total of 1,690 residents were included, with an overall mean number (and standard deviation) of 1.2 ± 2.4 publications per resident. Eighty-seven programs reported block time, 14 programs reported longitudinal time, and 24 programs reported no time. There was a significant difference (p = 0.02) in the mean number of publications per resident when compared between programs with protected time (1.1 ± 1.2 publications) and programs with no protected time (0.6 ± 0.5 publication). One-way ANOVA demonstrated a significant mean difference across the 3 groups (p < 0.001), with longitudinal time correlating with significantly greater output at 1.9 ± 1.8 publications than block time at 1.0 ± 1.0 publication or no time at 0.6 ± 0.5 publication, a difference that persisted when adjusted to include only impact factors of >0 and exclude case reports (p = 0.0015).

Conclusions:
Both the presence of and the type of dedicated research time correlate with residents’ research productivity; further consideration of protected research time during residency is warranted.

Clinical Relevance:
This article provides objective data with regard to research strategies in training orthopaedic surgeons.
The Fourth Year of Medical School: Time for Reassessment
Authors: Alman Benjamin A. , Purtill James J. , Pellegrini Vincent D. , Scoles Peter 
Published: July 2017

Abstract:
Most U.S. medical schools follow the 4-year model, consisting of 2 preclinical years, core clinical experience, and a fourth year intended to permit students to increase clinical competency, to explore specialty areas, and to transition to residency. Although the design and delivery of Years 1 through 3 have evolved to meet new challenges and expectations, the structure of Year 4 remains largely unchanged. For most students considering a career in orthopaedics, Year 4 is a series of elective rotations in which educational objectives become secondary to interviewing for residency programs. Most accreditation bodies recognize the importance of attainment of competency over the duration of medical school as the goal of educating physicians, and thus, there is a growing interest in reexamining the traditional medical school curriculum with the goal of integrating the final phases of undergraduate education and the first phases of postgraduate education.
A literature search was undertaken to identify publications on the duration of medical education. Pilot approaches to competency-based integration of undergraduate medical school and postgraduate training in orthopaedic surgery were reviewed.
There have been few data suggesting that 4 years of medical education is superior to shorter-duration programs. Three approaches to competency-based integration of undergraduate medical school and postgraduate training are presented. Their goal is to use student and faculty time more effectively. Each approach offers the opportunity to lower the cost and to decrease the time required for Board Certification in Orthopaedic Surgery. Two approaches shorten the entire duration of medical school and graduate training by using various proportions of the fourth year to begin residency, and one approach expands the duration of orthopaedic training by starting in the fourth year of medical school and including training equivalent to a fellowship program into the residency experience.
The effectiveness of such programs will form the basis for revisions to the current orthopaedic training paradigm, resulting in a more effective, efficient, and integrated orthopaedic training curriculum.
An in Vivo Simulation of Isometry of the Anterolateral Aspect of the Healthy Knee
Authors: Kernkamp Willem A. , Van de Velde Samuel K. , Tsai Tsung-Yuan , van Arkel Ewoud R.A. , Asnis Peter D. , Nelissen Rob G.H.H. , LaPrade Robert F. , Zarins Bertram , Li Guoan 
Published: July 2017

Background:
To assess the isometry of theoretical lateral extra-articular reconstruction (LER), we evaluated theoretical grafts attached to various points on the lateral femoral condylar area and to either Gerdy’s tubercle or the anatomic attachment site of the anterolateral ligament to the tibia.

Methods:
In 18 subjects, healthy knees with no history of either injury or surgery involving the lower extremity were studied. The subjects performed a sit-to-stand motion (from approximately 90° of flexion to full extension), and each knee was studied using magnetic resonance and dual fluoroscopic imaging techniques. The 3-dimensional wrapping paths of each theoretical LER graft were measured. Grafts showing the least change in length during the sit-to-stand motion were considered to be the most isometric.

Results:
The most isometric attachment site on the lateral femoral epicondyle to either of the studied tibial attachment sites was posterior-distal to the femoral attachment site of the fibular collateral ligament. The LER graft had a mean change in length of approximately 3%. Moving the femoral attachment site anteriorly resulted in increased length of the graft with increasing flexion; more posterior attachment sites resulted in decreased length with increasing flexion. Moving the attachment site in the proximal-distal direction had a less profound effect. Moving the tibial attachment site from Gerdy’s tubercle to the tibial attachment site of the anterolateral ligament affected the overall isometric distribution on the lateral femoral epicondyle.

Conclusions:
The most isometric attachment site on the femur for an LER would be posterior-distal to the femoral attachment site of the fibular collateral ligament. Different length changes for LER grafts were identified with respect to different femoral attachment sites. Desirable graft fixation locations for treating anterolateral rotatory instability were found posterior-proximal to the femoral fibular collateral ligament attachment.

Clinical Relevance:
The present data could be used both in biomechanical studies and in clinical studies as guidelines for planning LER surgical procedures.
Outcomes and Complications of Reconstruction with Use of Free Vascularized Fibular Graft for Spinal and Pelvic Defects Following Resection of a Malignant Tumor
Authors: Houdek Matthew T. , Rose Peter S. , Bakri Karim , Wagner Eric R. , Yaszemski Michael J. , Sim Franklin H. , Moran Steven L. 
Published: July 2017

Background:
Following resection of malignant tumors of the spine and pelvis, reconstructive surgeons often face large structural defects. Unlike reconstruction in the extremities, wherein a free vascularized fibular graft (FVFG) is a highly utilized option for segmental osseous reconstruction, there are limited data on the use of an FVFG in the spine and pelvis. The aim of this study was to review our institution’s experience with reconstruction with use of an FVFG following oncological resection in the spine and pelvis.

Methods:
We reviewed 24 cases involving the use of an FVFG in reconstruction of segmental osseous defects of the spine and pelvis following oncological resection from 2000 to 2015. The cohort consisted of 12 male and 12 female patients with a mean age of 37 years and a mean follow-up of 5 years. Fifty-four percent of the reconstructions were spinopelvic or sacropelvic.

Results:
The overall 2, 5, and 10-year rate of survival was 76%, 55%, and 37%, respectively. With regard to disease-free survival, the overall 2, 5, and 10-year rate was 81%, 72%, and 48%. The overall rate of union was 86%, with a mean time to union of 7 months. Complications were common, with 83% of the patients sustaining at least 1 postoperative complication. Following the procedure, the mean Musculoskeletal Tumor Society rating was 53%.

Conclusions:
An FVFG provides a durable means of reconstruction of osseous defects in the spine and pelvis. Although patient function was acceptable following these large reconstructions, the rate of postoperative complications was high.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Arterial line fracture: an unusual complication of invasive blood pressure monitoring
Authors: Allen Lara , Netke Meenu 
Published: July 2017

SummaryArterial lines are routinely used for haemodynamic monitoring in critically ill patients and they are associated with a low incidence of major complications. We present a case of radial arterial cannula fracture which necessitated surgical removal. Ultrasound played a crucial role in both identifying the cannula fragment and aiding surgical retrieval. Arterial line fracture is a rare complication of arterial cannulation but patient safety could be improved through a revision of how cannulas are secured to prevent kinking, fatigue and subsequent fracture. We suggest arterial lines should have marked or coloured tips to aid practitioners in ensuring the entire cannula length is removed with the distal tip intact.
Comportamientos de riesgo y nivel de conocimiento de infecciones de transmisión sexual en estudiantes universitarios
Authors: Villafañe-Ferrer Lucy Margarita , González-Navarro Rocío Margarita 
Published: July 2017

Las infecciones de transmisión sexual constituyen un problema epidemiológico y clínico de primer orden en todo el mundo por las secuelas que pueden ocasionar y por sus consecuencias económicas. Los adolescentes y jóvenes, tienen mayor riesgo de presentarlas debido a factores como el inicio temprano de relaciones sexuales, la promiscuidad, entre otros. El objetivo de esta investigación fue determinar los comportamientos de riesgo y nivel de conocimiento de infecciones de transmisión sexual en estudiantes de Bacteriología. Estudio correlacional de corte transversal. Se aplicó un cuestionario para determinar comportamientos de riesgo y nivel de conocimiento a 128 estudiantes de Bacteriología. El 78,1 % de estudiantes encuestados si ha tenido relaciones sexuales. El 55 % ingiere bebidas alcohólicas antes de una relación sexual. A través del análisis estadístico se estableció asociación entre la presencia de ITS con el consumo de drogas (p=0,042). Los estudiantes presentaron un nivel de conocimiento regular. No se encontró asociación estadísticamente significativa entre los comportamientos de riesgo y el nivel de conocimiento (p> 0,05). Los resultados encontrados en esta investigación evidencian la necesidad de realizar actividades tendientes a la prevención y motivar cambios de comportamiento que permitan disminuir el riesgo de contagio de estas enfermedades.
Determinantes para la Práctica de Actividad Física en Estudiantes Universitarios
Authors: Caro-Freile Ana Isabel , Rebolledo-Cobos Roberto Carlos 
Published: July 2017

La actividad física hace referencia al movimiento corporal que genera gasto energético, su práctica frecuente mejora las funciones físicas y mentales; el transporte activo, las actividades cotidianas y la recreación corresponden a la forma más común de actividad física. En Colombia la mayor parte de la población es inactiva, los niños son más activos, pero esta condición disminuye con la edad, el porcentaje de universitarios que realizan actividad física es bajo, está práctica está condicionada por la motivación interna, la condición física, la disponibilidad de tiempo y el soporte social. El gusto por el deporte, el espíritu competitivo, el mejoramiento de la imagen corporal, el manejo del estrés y los beneficios para la salud son factores motivadores para la práctica de la actividad física en estudiantes universitarios; por otra parte la pereza, el miedo a lesionarse, la escases de escenarios deportivos y la inseguridad del entorno son las barreras más frecuentes para la realización de actividad física en esta población
Duazary: sus procesos y avances editoriales
Authors: Ceballos-Ospino Guillermo Augusto , Pérez-Anaya Oskarly 
Published: July 2017

La revista Duazary surgió en el 2004 y en ella se publica información científica sobre temas de Salud, desde perspectivas amplias y generales de la salud pública, hasta temas especializados y concretos de áreas clínicas. A partir del año 2007 ininterrumpidamente hasta la actualidad, ha sido clasificada en categoría C por Publindex – Colciencias; así mismo se encuentra indexada en más de treinta bases, directorios, repositorios e índices de las que se destacan CAB Abstracts, Emerging Sources Citation Index e Index Copernicus, de esta última, vale la pena destacar que entre más de 25 revistas colombianas que se postularon el año pasado, fue una de las seis aceptadas; de la misma forma en el reciente Ranking publicado por Sapiens Research ésta subió dos categorías ubicándose en la D6. Adicionalmente, la revista llega a una gran parte de nuestro país, a varios países de Latinoamérica y a España en Europa, debido a que muchos de los autores de los artículos publicados son oriundos de estos países
Synthesis and Biological Evaluations of Organoruthenium Scaffolds: A Comprehensive Update
Authors: Mondal Ashaparna , Paira Priyankar 
Published: July 2017

Background:
Currently ruthenium complexes are immerging as effective anticancer agents due to
their less toxicity, better antiproliferative and antimetastatic activity, better stability in cellular environment and
most importantly variable oxidation and co-ordination states of ruthenium allows binding this molecule with a
variety of ligands. So in past few years researchers have shifted their interest towards organoruthenium complexes
having good fluorescent profile that may be applicable for cancer theranostics. Nowadays, photodynamic
therapy has become more acceptable because of its easy and effective approach towards killing cancer
cells.

Objective:
Objective of this review article is to shed light on synthesis, characterization, stability and fluorescence
studies of various ruthenium [Ru(II) and Ru(III)] complexes and different bioactivity studies conducted
with the synthesized compounds to test their candidacy as potent chemotherapeutic agents.

Methods:
Various heterocyclic ligands containing N,O and S as heteroatom mainly were prepared and
subjected to complexation with ruthenium-p-cymene moiety. In most cases [Ru(η6-p-cymene)(µ-Cl)Cl]2 was
used as ruthenium precursor and the reactions were conducted in various alcohol medium such as methanol,
ethanol or propanol. The synthesized complexes were characterized by 1H NMR and 13C NMR spectroscopy,
GC-MS, ESI-MS, elemental analysis and single crystal X-ray crystallography methods. Fluorescence study and
stability study were conducted accordingly using water, PBS buffer or DMSO. Stable compounds were
considered for cell viability studies. To study the efficacy of the compounds in ROS generation as
photosensitizers, in few cases, singlet oxygen quantum yields in presence of light were calculated. Suitable
compounds were selected for in vitro & in vivo antiproliferative, anti-invasive activity studies.

Result:

Many newly synthesized compounds were found to have less IC50 compared to a standard drug cysplatin.
Those compounds were also stable preferably in physiological conditions. Good fluorescence profile
and ROS generation ability were observed for few compounds.

Conclusion:
Numerous ruthenium complexes were developed which can be used as cancer theranostic agents.
Few molecules were synthesized as photosensitizers which were supposed to generate reactive singlet oxygen
species in targeted cellular environment in presence of a particular type of light and thereby ceasing cancer cell
growth.
Pengembangan Media Pembelajaran Berbasis Moodle pada Matakuliah Fisika Dasar
Authors: Herayanti Lovy , Habibi Habibi , Fuaddunazmi M 
Published: July 2017

Abstract. The purpose of this research is to develop "learning media based on moodle" for Basic Physics lecture. The study was conducted with 4D development medel for 2 years. In the first year, research focused on developing the moodle platform through define, design, and develop phases. The second year, performed refinement with product re-validation and disseminate. The development of moodle platform design is done offline and online using moodle software version 2.0. Offline development is done to organize story boards, page navigation, profile settings, administration settings, and management course settings. Online development is done so that Basic Physics learning can be accessed anywhere, so that students can learn more easily and flexibly. The results of the development and field tests show that the developed product is declared eligible to be used to support the learning process. Students responded positively to the moodle-based media developed.
PENGARUH PERBEDAAN INTENSITAS CAHAYA DAN PENYIRAMAN PADA PERTUMBUHAN JAGUNG (ZEA MAYS L.) ‘SWEET BOY-02’
Authors: Akmalia Hafidha Asni 
Published: July 2017

AbstrakIntensitas cahaya dan ketersediaan air merupakan faktor-faktor yang menjadi penunjang maupun penghambat pertumbuhan tergantung kisaran yang mampu diterima tanaman. Tujuan penelitian ini adalah untuk mengetahui pengaruh intensitas cahaya dan penyiraman terhadap pertumbuhan tanaman jagung. Rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap dengan 3 faktor intensitas cahaya (L1 : 63694 ; L2 : 11408 dan L3 : 3897 Lux) dan 3 faktor penyiraman (pemberian air sebanyak W1 : 2 L; W2 : 1,6 L; W3 : 1,2 L). Tiap kombinasi perlakuan dibuat tiga ulangan. Penanaman jagung dilakukan di lahan Sawitsari, Yogyakarta. Jagung dipanen saat berumur 75 hari dengan karakter pertumbuhan yang diamati meliputi tinggi tanaman, jumlah daun, rasio daun, berat kering tanaman, dan rasio akar-tajuk. Data dianalisis menggunakan Analisis Sidik Ragam Varian (Anava) dilanjutkan dengan uji Duncan’s Multiple Range Test (DMRT) pada tingkat signifikansi 5%. Hasil penelitian menunjukkan bahwa L1W1 (63694 Lux ; 2 L) menyebabkan semua karakter pertumbuhan meningkat.Kata kunci : jagung, pertumbuhan, intensitas cahaya, penyiraman AbstractThe light intensity and water availability are the factors both supporting and supressing plant growth and it depends on which level that plant can accept. The aim of this research was to evaluate the effect of light intensity and watering in maize growth. This research used Randomized Completed Design with 3 regimes of light intensity (L1 : 63694, L2 : 11408 dan L3 : 3897 Lux) and 3 regimes of watering (W1 : 2 L, W2 : 1,6 L and W3 : 1,2 L). Each combination was done with 3 replications and it was done in Sawitsari, Yogyakarta. Maize was harvested in 75 days after the treatment and the measured parameters were plant height, leaf total number, leaf ratio, root-shoot ratio, and plant biomass. Data were analyzed by Anava and DMRT test with significance level of 5%. The results showed that L1W1 treatment increased all parameters of growth. Keywords: maize, growth, light intensity, watering
“Os imaginativos meios que a natureza tem para extrair a vida de alguém” – representação do corpo envelhecido em <i>A máquina de fazer espanhóis</i>
Authors: Franz Marcelo 
Published: July 2017

<p>A velhice e a condição do velho na sociedade contemporânea são temas importantes no romance <em>A máquina de fazer espanhóis</em> (2012), do escritor português Valter Hugo Mãe. Ambientada num asilo, por meio das experiências do protagonista, o Sr. Silva, o romance faz uma complexa leitura da interação do velho com sua memória pessoal e sua participação na história social de seu tempo. Propomo-nos a observar, na análise do texto de Mãe,<em> </em>nuances e detalhes da representação do corpo envelhecido, vendo nisso ilustrações do significado do envelhecer em nossos dias. Amparamo-nos teoricamente no conceito de “biopoder”, desenvolvido por Michel Foucault. </p><p>---</p><p> </p><p><strong>DOI:</strong> <a href="http://dx.doi.org/10.22409/abriluff.2017n18a395" target="_blank">http://dx.doi.org/10.22409/abriluff.2017n18a395</a></p>