bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic variants and social benefit receipt in premenopausal women with breast cancer treated with docetaxel: a Danish population-based cohort study
Authors: Schmidt Julie A. , Hjorth Cathrine F. , Farkas Dóra K. , Damkier Per , Feddersen Søren , Hamilton-Dutoit Stephen , Ejlertsen Bent , Lash Timothy L. , Ahern Thomas P. , Cronin-Fenton Deirdre 
Published: September 2024

Abstract

Purpose
Breast cancer patients’ need for social benefits may increase following taxane-based chemotherapy, due to long-lasting side effects. Specific single nucleotide polymorphisms (SNPs) may mediate such side effects. We investigated the association between SNPs related to taxane metabolism, transport, toxicity, or DNA and neural repair, and receipt of social benefits.

Methods
From the Danish Breast Cancer Group, we identified premenopausal women diagnosed with stage I–III breast cancer during 2007–2011 and treated with docetaxel-based chemotherapy. We genotyped 21 SNPs from archived breast tumors using TaqMan assays. We ascertained social benefit payments from 1 year before to 5 years after diagnosis, using nationwide, administrative registry data. For each week, we categorized women as receiving health-related benefits (including sick leave and disability pension), labor market-related benefits (including unemployment benefits), or as being self-supporting. We computed rate ratios (RRs) of social benefit receipt for variant carriers (heterozygotes plus homozygotes) vs. non-carriers, using negative binominal regression with robust variance estimation.

Results
Among 2430 women, 12% received health-related benefits before diagnosis, 80% at diagnosis, and ~ 24% 2 to 5 years after diagnosis. Labor market-related benefits were uncommon (3–6%). All RRs were near-null and/or imprecise.

Conclusion
We found no clinically meaningful impact of the selected SNPs on social benefit receipt among premenopausal breast cancer survivors treated with docetaxel.
The Ethics of Human Embryo Editing via CRISPR-Cas9 Technology: A Systematic Review of Ethical Arguments, Reasons, and Concerns
Authors: Wiley Lindsay , Cheek Mattison , LaFar Emily , Ma Xiaolu , Sekowski Justin , Tanguturi Nikki , Iltis Ana 
Published: September 2024

AbstractThe possibility of editing the genomes of human embryos has generated significant discussion and interest as a matter of science and ethics. While it holds significant promise to prevent or treat disease, research on and potential clinical applications of human embryo editing also raise ethical, regulatory, and safety concerns. This systematic review included 223 publications to identify the ethical arguments, reasons, and concerns that have been offered for and against the editing of human embryos using CRISPR-Cas9 technology. We identified six major themes: risk/harm; potential benefit; oversight; informed consent; justice, equity, and other social considerations; and eugenics. We explore these themes and provide an overview and analysis of the critical points in the current literature.
Lau v. Nichols revisited: unveiling dual language program disparities in California for Asian students and marginalized communities
Authors: Ee Jongyeon , Sung Kenzo K. 
Published: September 2024

AbstractCalifornia has witnessed substantial growth in multilingual programs over the past half-century since the foundational Lau v. Nichols decision, with one in seven public schools statewide offering such programs for students. Likewise, the rapid rise in California’s Asian population, as well as the increase in both overall racial diversity and socioeconomic disparities across the state, have influenced dual language bilingual education discussions. Commemorating the fiftieth anniversary of the Lau decision, this study examines the impact of school and community characteristics on the availability of dual language programs in California public schools, with particular focus on the state’s Asian student population. Employing logistic regression analysis to delve into the American Community Survey and California Department of Education datasets, the study specifically examines how student demographics and school characteristics (e.g., grade level, charter, and magnet status), as well as community features (e.g., the share of foreign-born populations and median household income), are associated with the offering of dual language programs in California schools. Despite the considerable growth of the state’s Asian American population, the study could not find a meaningful connection between Asian representation and the provision of dual language programs. In addition, the results reveal severe equity concerns regarding low-income students’ access to dual language programs. Charter schools also tend to underutilize dual language programs compared to their non-charter counterparts. Based on the study’s findings, we raise concerns regarding why the presence of Asian students cannot be better leveraged as a driving force for implementing dual language programs in California’s public schools and highlight the persistent disparities faced by economically disadvantaged students.
Roads as Othering Spaces: Driverless Vehicles, the Roadscape, and the Human
Authors: Robb Lachlan , Marusek Sarah 
Published: September 2024

AbstractThe road represents a unique transitional space that removes a certain amount of humanity from drivers. Through changes in the built environments, or roadscapes, speed and spatial entitlement transforms the interactions between cars, cyclists, and pedestrians. No longer ‘people’, vehicular implementation of car worship culture de-personalizes humanity in these ‘othering’ spaces in lieu of automated technology that anonymizes movement. This creates an ‘othering’ process of road users that can invite aggression, impatience, and selfishness in ways that people would not ordinarily act towards one another. Recognising the nature of this process is important as societies move towards rethinking the built environment of roads, highways, car parks, and even the nature of cars themselves. This paper critically looks to how the road is a space where drivers interact with cars, cyclists, and pedestrians in ways that conceptually tether Hart’s notion of justice to Augé’s modernity of non-places through the mediation of legal culture through automobile technology and multiautoculturalism through the regulatory development of roadspace for cultural negotiation. Understanding the relationship between roads and humanity will be important to understanding how these futures may unfold, especially with the development and social implementation of autonomous vehicles.
Study on Initial Corrosion Behavior of Arc-thermally Spray Zn, Zn–Al, and Al–Mg Coatings Exposed in Atmospheric Environment for One-Year
Authors: Nakano Atsushi , Toyota Yuki , Morita Chihiro , Yasui Kentaro , Oshikawa Wataru , Yonezawa Noboru 
Published: September 2024

AbstractThis paper presents the results of a study comparing the initial corrosion characteristics of thermal spray coatings on Zn, Zn-Al, and Al–Mg thermal spray coatings after one year atmospheric exposure tests at two atmospheric environment sites. The thermal spray coatings were obtained by electroric arc spraying of various metals onto a carbon steel substrate. Atmospheric exposure tests were also conducted for outdoor accelerated exposure tests in which test specimens were applied with artificial seawater. The corrosion properties of these spray coatings were evaluated by surface analysis, film thickness measurements, cross-sectional analysis and anodic/cathodic polarization measurement. After one year of atmospheric exposure testing, white, granular corrosion products were observed on the surface of the Zn and Zn-Al thermal spray coatings, while no significant changes were observed in the Al–Mg thermal spray coating. Similar results were obtained for the surfaces of test specimens in atmospheric exposure tests with artificial seawater. The thickness of the thermal spray coating increased for the Zn thermal spray coating, while no significant change was observed for the other thermal spray coatings. Thus, differences in corrosion behavior were observed due to the composition of the thermal spray coatings. The initial corrosion behavior of the thermal spray coatings was also investigated based on the results of coating morphology and cross-sectional elemental distribution of the coatings.
Robustness-Based Approach for Slack Time Optimization in Tram Timetables
Authors: Zhou Weixia , Teng Jing , Chen Enhui 
Published: September 2024

AbstractConsidering the unique interplay of trams with road traffic, this study explored the issue of instability in tram operations—a prominent medium-capacity rail transit. Our goal was to design a timetable slack time optimization method for scheduling slack time to improve the stability of tram operations. To facilitate this, we derived the travel/dwelling time distribution from historical data, which assisted in estimating interference times and evaluating the requisite slack time. We then developed an integer programming model to calculate both the punctuality rate and expected delay under varying travel times, enabling the creation of alternative slack time schemes. Using a unique tram operation simulation logic, we assessed the operational efficiency and reliability of these alternate schemes based on specific operational indicators. The results suggest that our novel approach to timetable optimization significantly enhances the tram’s adaptability to disruptions, directly improving the passenger experience and tram competitiveness. This work offers a robust framework for timetable optimization for semi-independent right-of-way public transportation.
Online path tracking with an integrated H∞ robust adaptive controller for a double-Ackermann steering robot for orchard waypoint navigation
Authors: Shamshiri Redmond R. , Azimi Alireza , Behjati Maryam , Ghasemzadeh Aliakbar , Dworak Volker , Weltzien Cornelia , Karydis Konstantinos , Cheein Fernando A. Auat 
Published: September 2024

AbstractNavigation of agricultural mobile platforms in small-scale orchards poses challenges due to narrow row-end turning spaces and the need for precise path tracking in the presence of disturbances. The objective of this study is to improve path following and rapid turning maneuvers for a double-Ackermann steering robot by employing a simulation approach for PID-based waypoint following enhanced by learning-based H∞robust adaptive control. With the zero-speed turning radius of the robot measured at 2.85 m, the primary question to address is determining the minimum achievable turning radius using the two controllers. For this purpose, a versatile framework for fine-tuning and analyzing of the controllers is presented in MATLAB Simulink blocks interfaced with the virtual replica of the robot in CoppeliaSim. A comparative study between the controllers is carried out involving three experiments: offline path following with a fixed number of predefined waypoints, online path following with continuously updated waypoints forming paths, and path tracking with disturbance rejection using the H∞controller to reduce the radius of row-end turnings. Results indicate that while the PID controller achieves a minimum row-end turning radius of 3.0 m, the learning-based H∞controller surpasses it with a minimum radius of 2.9 m. It is observed that a minimum of 4 waypoints is required for the PID controller to perform effective row-end turning in the offline experiment, with a higher number of waypoints enabling the robot to navigate through complex geometries and tight turns more effectively. Moreover, by incorporating an actor-critic structure, it has been demonstrated that the learning-based H∞controller maintains stability even when facing wheel slippage disturbances, and outperforms the PID controller in online path tracking, particularly when maneuvering along a half-circle path. The framework proposed in this study contributes to improving autonomous navigation, particularly in determining the optimal number of waypoints and path configurations required for navigating agricultural robots with varying dimensions and steering mechanisms.
Digital Staff Support Interventions for the Psychological Wellbeing of Healthcare Professionals: A Systematic Review
Authors: Paleri Vigneshwar , Valmaggia Lucia , Kaleva Ina , Martland Rebecca , Riches Simon 
Published: September 2024

AbstractHealthcare professionals experience stressful events which impact on overall wellbeing. The rise of digital interventions marks an opportunity to support healthcare professionals in their psychological wellbeing. This systematic review aims to assess the feasibility, acceptability and effectiveness of digital interventions for healthcare professionals in mental and physical healthcare to improve psychological wellbeing (PROSPERO CRD42023394966). Four electronic databases (Embase, MEDLINE, PsycINFO and Web of Science) were searched, from inception, until 10 June 2024. The review was carried out according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The Effective Public Health Practice Project (EPHPP) tool was used to assess the methodological quality of studies. Thirty-five studies were included (N = 5364, published 2004–2024), including 13 randomised controlled trials. The majority of the studies were carried out in Europe and North America (mostly UK and USA). Digital interventions varied across format (e.g. web based, virtual reality based) and content type (e.g. biofeedback training). The most frequently used format for digital interventions were smartphone apps with the most common digital intervention type being general stress management programmes. Thirty-three studies indicated significant changes in at least one wellbeing measure, such as depression, anxiety, stress, resilience or compassion. On the EPHPP, 4 studies were rated strong, 14 were rated as moderate and 17 were rated as weak. Evidence suggests that digital interventions are a feasible, acceptable and effective approach to support wellbeing in healthcare professionals, although there are significant methodological limitations. Further research would benefit from stronger methodological designs, maximising participant engagement, and greater, more diverse sample sizes.
What roles can democracy labs play in co-creating democratic innovations for sustainability?
Authors: Campos Inês , Fuchs Doris , Repo Petteri , Jager Wander , Klöckner Christian , Wang Shaoni , Lamas David , Cots Francesc , Barchiesi Eugenio , Löfström Erica , Peniche Daniel , Sion Yulia , Buth Vanessa , Limão João , Oliveira Sandra , Diaz Claudia Reyes , Živčič Lidija 
Published: September 2024

AbstractThis perspective essay proposes Democracy Labs as new processes for developing democratic innovations that help tackle complex socio-ecological challenges within an increasingly unequal and polarised society, against the backdrop of democratic backsliding. Next to the current socio-ecological crisis, rapid technological innovations present both opportunities and challenges for democracy and call for democratic innovations. These innovations (e.g., mini-publics, collaborative governance and e-participation) offer alternative mechanisms for democratic participation and new forms of active citizenship, as well as new feedback mechanisms between citizens and traditional institutions of representative democracy. This essay thus introduces Democracy Labs, as citizen-centred processes for co-creating democratic innovations to inspire future transdisciplinary research and practice for a more inclusive and sustainable democracy. The approach is illustrated with examples from a Democracy Lab in Lisbon, reflecting on requirements for recruiting participants, the relevance of combining sensitising, reflection and ideation stages, and the importance of careful communication and facilitation processes guiding participants through co-creation activities.
L’appropriation de la transmission des traumatismes par le droit: le préjudice transgénérationnel dans la jurisprudence de la Cour pénale internationale
Authors: Cohen Miriam , Teles Renan 
Published: September 2024

Résumé
La Cour pénale internationale s’est penchée récemment sur la question nouvelle de la réparation des préjudices transgénérationnels. Dans son analyse, la cour s’appuie sur un type de préjudice qui dépasse la victime immédiate et qui en vise une qui n’a vécu l’événement traumatique original, que par l’entremise d’un transfert générationnel. En ce qui concerne la réparation, il faut établir si ce préjudice est spécifique et autonome justifiant une reconnaissance et, par conséquent, une mesure de réparation. La question de réparer un préjudice transgénérationnel est d’actualité et encore peu étudiée en droit pénal international. Le présent article vise à apporter une contribution dans ce domaine en examinant la façon dont le préjudice transgénérationnel est juridiquement élaboré dans certains exemples s’inscrivant dans un contexte de violations massives et graves des droits humains. Enfin, l’article analyse la jurisprudence de la Cour pénale internationale, mettant en lumière les difficultés et les dilemmes générés par la reconnaissance des préjudices transgénérationnels dans la sphère juridique pénale.
Review of National Health Service England’s Emergency Preparedness, Resilience and Response Annual Assurance for 2021–2022
Authors: Wetherell William 
Published: September 2024

Abstract

Objective
National Health Service (NHS) England conducts annual assurance of NHS bodies in England’s readiness to respond to emergencies using its Core Standards for emergency preparedness, resilience, and response (EPRR). This review assessed whether the first complete EPRR assurance after England’s coronavirus disease (COVID-19) pandemic national response was performed successfully.

Methods
The primary outcome of interest was the quantity of information regarding applicable Core Standards held by NHS England at the end of that assurance. Secondary outcomes were variations between the number of applicable Core Standards and information held by NHS bodies about the number of applicable Core Standards.

Results
NHS England recorded the correct number of applicable Core Standards for 88 of the 124 NHS trusts in England which provided general hospital accommodation and services in relation to accidents or emergencies. It recorded an incorrect number of standards for 13 trusts and did not record the number of standards for 23 trusts.

Conclusion
NHS England’s EPRR assurance resulted in correct data not being recorded for over a quarter of the above NHS trusts. This review may also be of interest to other state-level bodies that rely on the high-level assurance of their ability to provide health care during emergencies.
Shrimps from a marine biodiversity hotspot: new records and molecular analysis of alpheids from the Fernando de Noronha Archipelago (Decapoda: Caridea)
Authors: Moraes Isabela R. R. , Pasinatto Karmine , Bochini Gabriel Lucas , Horch Amanda P. , Almeida Alexandre Oliveira , Terossi Mariana 
Published: September 2024

Abstract
The oceanic archipelago of Fernando de Noronha represents one of the most important regions for Brazilian marine biodiversity, and is considered a ‘no-take’ marine area under law. More than 130 crustacean species have already been registered in the archipelago, with a significant number of caridean shrimps. Almost half of these shrimps belong to the family Alpheidae, making them an important marker of the species composition of the region. This study provides five new records of alpheids for the archipelago. Samples were taken in 2019 and 2022 from six locations around Fernando de Noronha, using active search during low tide and SCUBA diving in subtidal zones. The new records are Alpheus agilis, A. angulosus, A. rudolphi, Automate dolichognatha sensu lato, and Salmoneus ortmanni, and their DNA sequences have been made available alongside geographical distribution, photographs, ecological notes, and species remarks. All DNA sequences (mitochondrial 16S and cytochrome oxidase I genes) generated were compared with sequences available in Genbank and, in some cases, our sequences are the first for the species. Through this update, a total of 46 species of caridean shrimps have been recorded from Fernando de Noronha. Here we highlight the importance of checklists as a tool to keep an updated record of species' distributions. Continuous study of the native fauna of one of the most important biodiversity hotspots on the Brazilian coast is essential to establish effective management and conservation plans for the region.
Do crisis narratives encourage redistribution? Australian housing policy debates during COVID-19
Authors: Petter Pandanus H. , Howard Cosmo 
Published: September 2024

Abstract
Crises create opportunities for policy change, yet the extent to which they encourage redistribution is under-researched. We adopt a narrative approach to study how crisis frames are mobilised to support or oppose redistribution, and whether that redistribution is progressive or regressive. A typology of crisis narratives with different redistributive implications is presented: retrenchment narratives promote deregulation and cuts to welfare; Robin Hood narratives advocate progressive redistribution with expanded rights; and restoration narratives favour bringing back the status quo ex ante. We apply the Narrative Policy Framework to examine how Australian parliamentarians used the language of ‘housing crisis’ during and after COVID-19. Despite existing research suggesting crisis narratives mostly support retrenchment, Australia’s pandemic housing debates were dominated by Robin Hood and restoration narratives. We show that party ideology matters for the redistributive content of crisis narratives, but the effect of ideology is mediated by incumbency status. We conclude that shifts in the parliamentary balance of power lead to changes in political parties’ rhetorical support for redistribution.
The Basque version of the CDI-words and gestures, extended up to age 2
Authors: Garcia Iñaki , Ezeizabarrena Maria-José , Murciano Aroa 
Published: September 2024

AbstractThe Basque version of the MacArthur-Bates Communicative Development Inventory (BCDI-1) can be used to evaluate 8–15-month-old children’s receptive and expressive verbal skills, as well as nonverbal gesture production. This paper reports on data of 1002 children of an extended age range obtained with the BCDI-1 as a proxy measure of Basque children’s communicative competence up to 24 months. Statistical analyses revealed a large effect of age on four BCDI-1 scales: phrases understood, production of gestures, receptive vocabulary, and expressive vocabulary, while sex, amount of exposure, educational level, and birth order showed small or no effect. The strong effect of age as well as the high between-scale correlations confirmed the advantage of using the BCDI-1 instrument for the extended age range.