bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives of Screening-Eligible Women and Male Partners on Benefits of and Barriers to Treatment for Precancerous Lesions and Cervical Cancer in Kenya
Authors: Ragan Kathleen R. , Buchanan Lunsford Natasha , Lee Smith Judith , Saraiya Mona , Aketch Millicent 
Published: August 2017

Abstract

Background
Cervical cancer is the leading cause of female cancer mortality in Kenya. Kenya's National Cervical Cancer Prevention Program Strategic Plan outlines efforts to reduce the burden; however, treatment services remain limited. This study identified male and female perspectives regarding benefits, facilitators, and barriers to treatment for precancerous lesions and cervical cancer.

Materials and Methods
Ten focus groups were conducted in Nairobi and Nyanza in 2014 with females aged 25–49 years (n = 60) and male partners (n = 40). Participants were divided into groups dependent on screening status, sex, language, and geographic location. Qualitative analytic software was used to analyze transcribed and translated data.

Results
Treatment was endorsed as beneficial for the prevention of death and the improvement of wellness, quality of life, symptoms, and family life. Barriers reported by males and females included the following: (a) concerns about side effects; (b) treatment-related fear and stigma; (c) marital discord; (d) financial and access issues; (e) religious and cultural beliefs; and (f) limited knowledge. Male endorsement of wanting to improve knowledge and communication with their partners, in spite of stigmatizing beliefs and misperceptions regarding females with abnormal screening results or those who have been diagnosed with cancer, was novel.

Conclusion
Incorporating qualitative data on benefits of and barriers to treatment for precancerous lesions and cervical cancer into Kenya's national priorities and activities is important. These findings can be used to inform the development and successful implementation of targeted, region-specific community outreach and health messaging campaigns focused on alleviating the country's cervical cancer burden.

Implications for Practice
This article provides important insight into female and male partner perspectives regarding benefits, facilitators, and barriers to treatment for precancerous lesions and cervical cancer. These novel research findings can inform the development of targeted community health interventions, educational messages, and resources and aid stakeholders in strengthening strategic plans regarding treatment coverage and cervical cancer prevention. Because several treatment barriers identified in this study are similar to barriers associated with cervical cancer screening in low- and middle-resourced countries, effective messaging interventions could address barriers to receipt of both screening and treatment.
Insecticide Residues on Poultry Manures: Field Efficacy Test on Selected Insecticides in Managing Musca Domestica Population
Authors: Song-Quan Ong  , Abdul Hafiz Ab Majid  , Hamdan Ahmad  
Published: August 2017

In this study, bifenthrin (Maxxthor SC, Ensystex Australasia Pty Ltd), imidacloprid (Prothor SC, Ensystex Australasia Pty Ltd) and fipronil (Regent®50SC, Bayer) were applied on the natural infest manures according to the manufacturer rate during a broiler breeding cycle. Solvent directimmersion extraction (SDIE) was used in detecting the target compound and later, quantification of the insecticide residues in field condition was investigated. The samples were prior cleaned up by solid-phase extraction (SPE) and analyzed by Ultra-Performance Liquid Chromatography (UPLC) - photodiode array (PDA) system. In the field trial, three insecticides were showed accumulation during the broiler breeding period and it is suggested that they acted as adulticides when applied on the poultry manures, this is supported by the significant correlation between the increment of insecticide residues to the reduction percentage of adult flies (<0.05). Fipronil showed significantly greater reduction on the adult fly compared to the other insecticides, in which the reduction rate compared to control population at the end of the broiler breeding period; fipronil, imidaclopril and bifenthrin reduced 51.51%, 28.30% and 30.84% of adult flies, respectively.

Dalam kajian ini, bifenthrin (Maxxthor SC, Ensystex Australasia Pty Ltd), imidacloprid (Prothor SC, Ensystex Australasia Pty Ltd) dan fipronil (Regent®50SC, Bayer) telah digunakan pada najis ayam yang dikerumuni oleh lalat Musca domestica secara semulajadi dalam satu penternakan ayam daging kitaran. Pengekstrakan rendaman pelarut (SDIE) telah digunakan dalam mengesan kompaun racun dan kemudian, kuantifikasi dan kualifikasi racun serangga pada keadaan bidang telah disiasat. Sampel telah dibersihkan dengan pengekstrakan fasa pepejal (SPE) dan dianalisis oleh Ultra-Performance Liquid Chromatography (UPLC) - sistem fotodiod pelbagai (PDA). Dalam kajian lapangan ayam, tiga racun serangga telah menunjukkan pengumpulan dalam tempoh penternakan ayam dan ia dicadangkan bahawa tiga racun serranga bertindak sebagai racun lalat dewasa walaupun digunakan pada najis ayam, ini telah disokongi dengan korelasi yang signifikan antara kenaikan sisa-sisa racun serangga kepada peratusan pengurangan daripada lalat dewasa (<0.05). Fipronil menunjukkan pengurangan lalat yang lebih tinggi berbanding dengan racun serangga yang lain, di mana kadar pengurangan berbanding untuk mengawal lalat pada akhir tempoh pembiakan ayam daging; fipronil, imidaclopril dan bifenthrin mengurangkan 51,51%, 28,30% dan 30,84% lalat dewasa, masing-masing.
Ephemeroptera, Plecoptera and Trichoptera (Insecta) Abundance, Diversity and Role in Leaf Litter Breakdown in Tropical Headwater River
Authors: Suhaila Ab Hamid  , Che Salmah Md Rawi  
Published: August 2017

Leaf litter decomposition in a tropical stream was examined in two types of leaf packs; single species leaf packs of Pometia pinnata and two species leaf packs of equal combination of Pometia pinnata and Dolichandrone spathacea leaves. Both leaf packs were immersed in a river and weekly examined for remains of decomposed leaves and presence of EPT. In the control leaf packs, leaves in the two species leaf packs treatments decomposed within 35 days, faster than in single species leaf packs which decomposed after 42 days. In the presence of EPT, the leaf breakdown took 28 days in two species and 35 days for single species leaf packs. Higher abundance of EPT was observed in single species leaf packs but its diversity was higher in two species leaf packs. Litter breakdown in the stream was faster in the presence of EPT and softer leaves of D.spathacea with higher nitrogen content underwent faster decomposition and sustained higher numbers of EPT.

Penguraian sampah daun di dalam aliran tropika diperiksa dalam dua jenis pek daun; Pek daun spesis tunggal Pometia pinnata dan dua pek daun spesis yang sama dengan kombinasi Pometia pinnata dan daun Dolichandrone spathacea. Kedua-dua pek daun telah direndam di dalam sungai dan diperiksa setiap minggu untuk sisa-sisa daun terurai dan kehadiran EPT. Dalam pek daun kawalan, daun dalam dua pek spesies rawatan daun terurai dalam masa 35 hari, lebih cepat daripada satu pek daun spesies tunggal yang terurai selepas 42 hari. Pecahan daun mengambil masa 28 hari dalam dua spesies dan 35 hari untuk pek daun spesies tunggal dengan kehadiran EPT. Kelimpahan EPT yang lebih tinggi diperhatikan dalam pek daun spesis tunggal tetapi kepelbagaiannya lebih tinggi dalam dua pek daun spesis. Kerosakan sampah di aliran lebih cepat dengan kehadiran EPT dan daun lembut D.spathacea dengan kandungan nitrogen yang lebih tinggi mengalami penguraian lebih cepat dan mempertahankan jumlah EPT yang lebih tinggi.
Avaliação da rotulagem da qualidade microbiológica e físico-química de polpas de frutas comercializadas em Picos-PI
Authors: Feitosa Raíssa Carvalho , Sousa Ana Cibele Pereira , Teixeira Sabrina Almondes , Medeiros Stella Regina Arcanjo 
Published: August 2017

Este trabalho objetivou avaliar as características de rotulagem e dos parâmetros físico-químico, microbiológicos e da temperatura de acondicionamento de três marcas comerciais de polpas de acerola (A1, A2, A3) e tamarindo (T1, T2, T3) comercializadas nos supermercados na cidade de Picos-PI. Nenhuma amostra estava adequada quanto à temperatura. Apenas duas amostras estavam totalmente adequadas em relação à rotulagem. Os resultados físico-químicos demonstraram que as polpas se encontram de acordo com o padrão da legislação vigente. As análises microbiológicas foram negativas para coliformes à 45°C e também para salmonela, os resultados obtidos demonstram que as polpas podem ser consumidas de maneira segura, pois se encaixam dentro dos padrões higiênico-sanitários determinados.
Rodrigo Caro, Días geniales o lúdicros. Edición, estudio preliminar y notas por Jean-Pierre Etienvre. Espasa-Calpe, Madrid, 1978; 2 ts.: cxvi + 210, 291 pp.
Authors: Campbell Ysla 
Published: August 2017

Se reseñó el libro: Días geniales o lúdicros.
TUNTUTAN PROVISI DALAM GUGATAN PELANGGARAN MEREK PADA PENGADILAN NIAGA
Authors: Martana Devi Marlita 
Published: August 2017

Act Number 15 Year 2001 regarding Trademark has set the provisional charges. Provisional charges may be filed by the plaintiff while the investigation process of trademark infringement lawsuit in court of commerce is still ongoing. In a civil proceeding, the provisional charge must not be the primary charge, however the provisional charge that is set out in the Trademark Act has already concerned the primary charge. Actions that can be requested in the provisional charge according to Article 78 paragraph (1) in the Trademark Act include cessation of production, cessation of circulation of goods and / or services using Plaintiff's trademark illegally. Using literature study that utilizes primary legal materials and secondary legal materials as the research object, the results of the discussion are expected to be based on sufficient arguments to provide benefits for those who are interested to learn the trademark law enforcement.
APLIKASI KONSORSIUM MIKROBA UNTUK MEREMEDIASI TANAH TERKONTAMINASI TIMBAL DARI LIMBAH PROSES DEINKING INDUSTRI KERTAS
Authors: Septiningrum Krisna , Hardiani Henggar 
Published: August 2017

Lead contaminated soil bioremediation using microbial consortium has been conducted on laboratorioum scale. Four types of lead accumulating bacteria, PG 65-06 (A): PG 97-02 (B): MR 1.12-05 (C) and A1 (D) with a ratio of 1:1:1:1 is used as microbial consortium. The study was conducted in 60 days with microbial inoculum variation of 5%, 10%, 15% (v/w) and the addition of 5% microbial inoculum with rice straw as bulking agents. Observations were conducted every 10 days which concentration of Pb, microbial activity, physico-chemical properties of soil before and after bioremediation as parameters. The addition of microbial consortium was proficient to remediate lead contaminated soil with a higher rate than the addition of 5% microbial inoculum with rice straw, which characterized by decreasing concentrations of soluble-exchangeable lead into residuals lead. The optimal condition occured in 40 days of incubation for addition of microbial inoculum 10% (v/w), and 50 days incubations for addition of 5% microbial inoculum with rice straw. The additions of rice straw enhanced indigenous microbial activity indicated by increasing quantity of soil microbes and CO2 production compared to addition of microbial inoculum. Characteristics of contaminated soil that has been remediated by microbes’ consortium improved because the content of the soil macronutrients and micronutrients in remediated soil was better than previous.Key words : bioremediation, lead, microbes consortium, deinkingABSTRAKBioremediasi tanah yang terkontaminasi timbal (Pb) menggunakan konsorsium mikroba telah dilakukan pada skala laboratorium. Empat jenis bakteri pengakumulasi Pb, PG 65-06 (A): PG 97-02 (B): MR 1.12-05 (C) dan A1 (D) dengan perbandingan 1:1:1:1 digunakan sebagai konsorsium mikroba. Penelitian dilakukan selama 60 hari dengan variasi penambahan inokulum mikroba 5%, 10%, 15% (v/w) dan penambahan inokulum 5%+ jerami padi sebagai bulking agents. Pengamatan dilakukan setiap 10 hari sekali dengan parameter konsentrasi logam Pb, aktivitas mikroba tanah, serta analisis sifat fisika-kimia tanah pada awal dan akhir proses bioremediasi. Penambahan konsorsium mikroba dapat mempercepat proses remediasi logam Pb pada tanah terkontaminasi dibandingkan dengan konsorsium mikroba 5%+jerami, yang ditandai dengan menurunnya konsentrasi logam Pb dari fase tertukarkan menjadi fase residual. Perubahan fase tersebut optimal pada waktu inkubasi 40 hari pada penambahan inokulum 10% (v/w) dan pada waktu inkubasi 50 hari pada penambahan mikroba 5%+jerami. Penambahan jerami meningkatkan aktivitas mikroba indigenous yang ditunjukkan dengan meningkatnya jumlah mikroba tanah dan produksi CO2 yang dihasilkan dibandingkan penambahan inokulum mikroba. Karakteristik tanah terkontaminasi yang telah diremediasi oleh konsorsium mikroba menjadi lebih baik karena kandungan unsur hara tanah baik makro maupun mikro meningkat dibandingkan sebelum diremediasi.Kata kunci : bioremediasi, Pb, konsorsium mikroba, deinking
Andi Selle dalam Pergolakan Bersenjata di Sulawesi Selatan (1950-1964)
Authors: Abidin Sainal 
Published: August 2017

This paper describes the background, role and impact of the involvement of Andi Selle in the throes of armed in South Sulawesi. This research is both a descriptive analysis using historical methods, through stages: heuristic, interpretation, criticism, and historiography. The involvement of Andi Selle in the throes of armed internal conflict caused by the TNI in the body. Armed upheaval since before independence until the period of independence Andi Selle was involved in a series of conflicts with some of the parties. The upheaval affect ethnic hatred caused his soldiers are considered acts of violence hurt the people's Rail, as well as the monopoly of trade in the region.
Timing of cranioplasty: a 10.75-year single-center analysis of 754 patients
Authors: Morton Ryan P. , Abecassis Isaac Josh , Hanson Josiah F. , Barber Jason K. , Chen Mimi , Kelly Cory M. , Nerva John D. , Emerson Samuel N. , Ene Chibawanye I. , Levitt Michael R. , Chowdhary Michelle M. , Ko Andrew L. , Chesnut Randall M. 
Published: August 2017

OBJECTIVEDespite their technical simplicity, cranioplasty procedures carry high reported morbidity rates. The authors here present the largest study to date on complications after cranioplasty, focusing specifically on the relationship between complications and timing of the operation.METHODSThe authors retrospectively reviewed all cranioplasty cases performed at Harborview Medical Center over the past 10.75 years. In addition to relevant clinical and demographic characteristics, patient morbidity and mortality data were abstracted from the electronic medical record. Cox proportional-hazards models were used to analyze variables potentially associated with the risk of infection, hydrocephalus, seizure, hematoma, and bone flap resorption.RESULTSOver the course of 10.75 years, 754 cranioplasties were performed at a single institution. Sixty percent of the patients who underwent these cranioplasties were male, and the median follow-up overall was 233 days. The 30-day mortality rate was 0.26% (2 cases, both due to postoperative epidural hematoma). Overall, 24.6% percent of the patients experienced at least 1 complication including infection necessitating explantation of the flap (6.6%), postoperative hydrocephalus requiring a shunt (9.0%), resorption of the flap requiring synthetic cranioplasty (6.3%), seizure (4.1%), postoperative hematoma requiring evacuation (2.3%), and other (1.6%).The rate of infection was significantly higher if the cranioplasty had been performed < 14 days after the initial craniectomy (p = 0.007, Holm-Bonferroni–adjusted p = 0.028). Hydrocephalus was significantly correlated with time to cranioplasty (OR 0.92 per 10-day increase, p < 0.001) and was most common in patients whose cranioplasty had been performed < 90 days after initial craniectomy. New-onset seizure, however, only occurred in patients who had undergone their cranioplasty > 90 days after initial craniectomy. Bone flap resorption was the least likely complication for patients whose cranioplasty had been performed between 15 and 30 days after initial craniectomy. Resorption was also correlated with patient age, with a hazard ratio of 0.67 per increase of 10 years of age (p = 0.001).CONCLUSIONSCranioplasty performed between 15 and 30 days after initial craniectomy may minimize infection, seizure, and bone flap resorption, whereas waiting > 90 days may minimize hydrocephalus but may increase the risk of seizure.
Melanoma brain metastasis: the impact of stereotactic radiosurgery, BRAF mutational status, and targeted and/or immune-based therapies on treatment outcome
Authors: Kotecha Rupesh , Miller Jacob A. , Venur Vyshak A. , Mohammadi Alireza M. , Chao Samuel T. , Suh John H. , Barnett Gene H. , Murphy Erin S. , Funchain Pauline , Yu Jennifer S. , Vogelbaum Michael A. , Angelov Lilyana , Ahluwalia Manmeet S. 
Published: August 2017

OBJECTIVEThe goal of this study was to investigate the impact of stereotactic radiosurgery (SRS), BRAF status, and targeted and immune-based therapies on the recurrence patterns and factors associated with overall survival (OS) among patients with melanoma brain metastasis (MBM).METHODSA total of 366 patients were treated for 1336 MBMs; a lesion-based analysis was performed on 793 SRS lesions. The BRAF status was available for 78 patients: 35 had BRAFmut and 43 had BRAF wild-type (BRAF-WT) lesions. The Kaplan-Meier method evaluated unadjusted OS; cumulative incidence analysis determined the incidences of local failure (LF), distant failure, and radiation necrosis (RN), with death as a competing risk.RESULTSThe 12-month OS was 24% (95% CI 20%–29%). On multivariate analysis, younger age, lack of extracranial metastases, better Karnofsky Performance Status score, and fewer MBMs, as well as treatment with BRAF inhibitors (BRAFi), anti–PD-1/CTLA-4 therapy, or cytokine therapy were significantly associated with OS. For patients who underwent SRS, the 12-month LF rate was lower among those with BRAFmut lesions (6%, 95% CI 2%–11%) compared with those with BRAF-WT lesions (22%, 95% CI 13%–32%; p < 0.01). The 12-month LF rates among lesions treated with BRAFi and PD-1/CTLA-4 agents were 1% (95% CI 1%–4%) and 7% (95% CI 1%–13%), respectively. On multivariate analysis, BRAF inhibition within 30 days of SRS was protective against LF (HR 0.08, 95% CI 0.01–0.55; p = 0.01). The 12-month rates of RN were low among lesions treated with BRAFi (0%, 95% CI 0%–0%), PD-1/CTLA-4 inhibitors (2%, 95% CI 1%–5%), and cytokine therapies (6%, 95% CI 1%–13%).CONCLUSIONSPrognostic schema should incorporate BRAFi or immunotherapy status and use of targeted therapies. Treatment with a BRAF inhibitor within 4 weeks of SRS improves local control without an increased risk of RN.
Vitamin D status and 3-month Glasgow Outcome Scale scores in patients in neurocritical care: prospective analysis of 497 patients
Authors: Guan Jian , Karsy Michael , Brock Andrea A. , Eli Ilyas M. , Manton Gabrielle M. , Ledyard Holly K. , Hawryluk Gregory W. J. , Park Min S. 
Published: August 2017

OBJECTIVEVitamin D deficiency has been associated with a variety of negative outcomes in critically ill patients, but little focused study on the effects of hypovitaminosis D has been performed in the neurocritical care population. In this study, the authors examined the effect of vitamin D deficiency on 3-month outcomes after discharge from a neurocritical care unit (NCCU).METHODSThe authors prospectively analyzed 25-hydroxy vitamin D levels in patients admitted to the NCCU of a quaternary care center over a 6-month period. Glasgow Outcome Scale (GOS) scores were used to evaluate their 3-month outcome, and univariate and multivariate logistic regression was used to evaluate the effects of vitamin D deficiency.RESULTSFour hundred ninety-seven patients met the inclusion criteria. In the binomial logistic regression model, patients without vitamin D deficiency (> 20 ng/dl) were significantly more likely to have a 3-month GOS score of 4 or 5 than those who were vitamin D deficient (OR 1.768 [95% CI 1.095–2.852]). Patients with a higher Simplified Acute Physiology Score (SAPS II) (OR 0.925 [95% CI 0.910–0.940]) and those admitted for stroke (OR 0.409 [95% CI 0.209–0.803]) or those with an “other” diagnosis (OR 0.409 [95% CI 0.217–0.772]) were significantly more likely to have a 3-month GOS score of 3 or less.CONCLUSIONSVitamin D deficiency is associated with worse 3-month postdischarge GOS scores in patients admitted to an NCCU. Additional study is needed to determine the role of vitamin D supplementation in the NCCU population.
Limitations of multidetector computed tomography angiography for the diagnosis of blunt cerebrovascular injury
Authors: Grandhi Ramesh , Weiner Gregory M. , Agarwal Nitin , Panczykowski David M. , Ares William J. , Rodriguez Jesse S. , Gelfond Jonathan A. , Myers John G. , Alarcon Louis H. , Okonkwo David O. , Jankowitz Brian T. 
Published: August 2017

OBJECTIVEBlunt cerebrovascular injuries (BCVIs) following trauma carry risk for morbidity and mortality. Since patients with BCVI are often asymptomatic at presentation and neurological sequelae often occur within 72 hours, timely diagnosis is essential. Multidetector CT angiography (CTA) has been shown to be a noninvasive, cost-effective, reliable means of screening; however, the false-positive rate of CTA in diagnosing patients with BCVI represents a key drawback. Therefore, the authors assessed the role of DSA in the screening of BCVI when utilizing CTA as the initial screening modality.METHODSThe authors performed a retrospective analysis of patients who experienced BCVI between 2013 and 2015 at 2 Level I trauma centers. All patients underwent CTA screening for BCVI according to the updated Denver Screening Criteria. Patients who were diagnosed with BCVI on CTA underwent confirmatory digital subtraction angiography (DSA). Patient demographics, screening indication, BCVI grade on CTA and DSA, and laboratory values were collected. Comparison of false-positive rates stratified by BCVI grade on CTA was performed using the chi-square test.RESULTSA total of 140 patients (64% males, mean age 50 years) with 156 cerebrovascular blunt injuries to the carotid and/or vertebral arteries were identified. After comparison with DSA findings, CTA findings were incorrect in 61.5% of vessels studied, and the overall CTA false-positive rates were 47.4% of vessels studied and 47.9% of patients screened. The positive predictive value (PPV) for CTA was higher among worse BCVI subtypes on initial imaging (PPV 76% and 97%, for BCVI Grades II and IV, respectively) compared with Grade I injuries (PPV 30%, p < 0.001).CONCLUSIONSIn the current series, multidetector CTA as a screening test for blunt cerebrovascular injury had a high-false positive rate, especially in patients with Grade I BCVI. Given a false-positive rate of 47.9% with an estimated average of 132 patients per year screening positive for BCVI with CTA, approximately 63 patients per year would potentially be treated unnecessarily with antithrombotic therapy at a busy United States Level I trauma center. The authors’ data support the use of DSA after positive findings on CTA in patients with suspected BCVI. DSA as an adjunctive test in patients with positive CTA findings allows for increased diagnostic accuracy in correctly diagnosing BCVI while minimizing risk from unnecessary antithrombotic therapy in polytrauma patients.