bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trust in parliament
Authors: Holmberg Soren , Lindberg Staffan , Svensson Richard 
Published: February 2017

Parliaments are—or should at least be—the central rule‐making institutions in democratic countries. If people do not have faith in the institution making the rules, it is less likely that people live by them. Consequently, it is beneficiary if trust in parliament is high. But it is also a normative good in itself. If the people do not trust the key institution whereby they can exercise “rule by the people over itself,” democracy itself is endangered. Secondly, trust levels should be reasonably even spread among relevant social and political groups in a society because parliament should ideally be a nonpartisan level playing field. However, because the majority in parliament typically chooses and sustains the acting government, one could say that legislatures in parliamentary democracies should not be level playing fields. According to this argument, there should be differences in trust in parliament between groups of individuals with varying political affiliations. Supporters of the majority in parliament should be expected to have higher trust in the legislature compared to citizens who voted for the opposition.We test our three hypotheses on data from some 80 countries participating in World Value Survey, either in Waves 5 or 6. We find that people in both new and established democracies harbor lower levels of trust than an intuitive interpretation of normative theory would lead us to expect. We also find that the attitudes of tens of thousands of citizens garnered from across 42 new and old democracies suggest that levels of average trust in groups of these societies are not as equally distributed, as a simple reading of democratic theory would have us to believe. In particular, individuals with a stronger interest in politics, and who are winners by the account of the last election, have statistically substantively relevant higher average levels of trust in parliament as an institution than do other citizens. The latter seems to us especially potentially problematic in particular for some of the new democracies where majority‐dominant parties manage to cling on to power over several election cycles. If what we find here were generally applicable also over several election cycles, we would expect the gap between winners and losers to widen and sediment and potentially sow the seeds of anti‐system movements opposed to democracy. Parliament is obviously a partisan creature in the eyes of most citizens in democracies. The level playing field idea does not fly.
Nanostructured polymer blends based on polystyrene‐b‐polybutadiene‐b‐poly(methyl methacrylate) triblock copolymers modified with polystyrene and/or poly(methyl methacrylate) homopolymers
Authors: Martin Loli , Irusta Lourdes , Gonzalez Alba , Tercjak Agnieszka , Kortaberria Galder 
Published: February 2017

AbstractMorphologies of polymer blends based on polystyrene‐b‐polybutadiene‐b‐poly(methyl methacrylate) (SBM) triblock copolymer were predicted, adopting the phase diagram proposed by Stadler and co‐workers for neat SBM block copolymer, and were experimentally proved using atomic force microscopy. All investigated polymer blends based on SBM triblock copolymer modified with polystyrene (PS) and/or poly(methyl methacrylate) (PMMA) homopolymers showed the expected nanostructures. For polymer blends of symmetric SBM‐1 triblock copolymer with PS homopolymer, the cylinders in cylinders core−shell morphology and the perforated lamellae morphology were obtained. Moreover, modifying the same SBM‐1 triblock copolymer with both PS and PMMA homopolymers the cylinders at cylinders morphology was reached. The predictions for morphologies of blends based on asymmetric SBM‐2 triblock copolymer were also confirmed experimentally, visualizing a spheres over spheres structure. This work presents an easy way of using PS and/or PMMA homopolymers for preparing nanostructured polymer blends based on SBM triblock copolymers with desired morphologies, similar to those of neat SBM block copolymers. © 2017 Society of Chemical Industry
Corrigendum to ‘Solar cell efficiency tables (version 49)’[Prog. Photovolt: Res. Appl. 2017; 25:3–13]
Authors: Green Martin A. 
Published: February 2017

AbstractVersion 49 of these efficiency tables reported confirmed new solar cell results from July – December 2016. Three errors are corrected and three new results received after the publication cut‐off date are briefly reviewed. Copyright © 2017 John Wiley & Sons, Ltd.
Identification of candidate biomarkers for the prediction of gestational diabetes mellitus in the early stages of pregnancy using iTRAQ quantitative proteomics
Authors: Zhao Danqing , Shen Liming , Wei Yan , Xie Jiaming , Chen Shuqiang , Liang Yi , Chen Youjiao , Wu Haorong 
Published: February 2017

PurposeGestational diabetes mellitus (GDM) is one of the most common medical problems of pregnancy. This study is designed to identify serum biomarkers, which can predict the subsequent development of GDM at early stages.Experimental designMaternal blood was obtained prospectively from pregnant women at 12–16 wk of pregnancy. Among these, 30 women were subsequently diagnosed with GDM at 24 to 28 wk and were selected as case studies along with 30 normoglycemic women as controls. Serum samples were analyzed by using iTRAQ analysis.ResultsThirty three differentially expressed proteins were identified between case and control groups. They were involved in various signaling processes previously implied in GDM. Of which four proteins, i.e. apolipoprotein E, coagulation factor IX, fibrinogen alpha chain, and insulin‐like growth factor‐binding protein 5 were successfully verified by ELISA. Combinations of these four proteins, the area under the receiver operating characteristic curve, sensitivity, and specificity were 0.985, 80% and 95%, respectively.ConclusionThe results highlight the roles of complement system, inflammatory and immune response, and blood coagulation in the pathogenesis of GDM. The panel of four candidate proteins could distinguish women subsequently developed with GDM from controls with high sensitivity and specificity.
Theoretical study of interaction of heteroaromatic compounds with a cluster model of kaolinite tetrahedral surface
Authors: Wang Liang , Wang Xing , Qian Ping , Guo Hong 
Published: February 2017

AbstractHeteroaromatic hydrocarbons (including thiophene [TH], benzothiophene [BT], and dibenzothiophene [DBT]) do not have apparent functional groups capable of interacting with the silica‐oxide tetrahedral surface of kaolinite. Thus, question remains concerning what would be the driving forces for the adsorption. Here, the Si13O37H22 cluster model for the surface is constructed, and the interactions of the surface with three heteroaromatic compounds are studied at the MP2/6‐31G(d,p)//B3LYP/6‐31G(d) level. The computed properties characterizing the complexes include optimized structural parameters, electron density characteristics (the ρ and ∇2ρ values for CH…O bonds), adsorption energies, vibration frequencies and electrostatic potential maps. The results suggest that the CH…O hydrogen bonding interactions between the heteroaromatic compounds and tetrahedral surface are likely among the important interactions for the adsorption. The order of the stability of the cluster model of kaolinite complexed with the heteroaromatic compounds is found to be 3SiODBT > 3SiOBT > 3SiOTH based on the calculations.
Changes in stable isotope ratios in PDO cheese related to the area of production and green forage availability. The case study of Pecorino Siciliano
Authors: Valenti Bernardo , Biondi Luisa , Campidonico Luca , Bontempo Luana , Luciano Giuseppe , Di Paola Fortunato , Copani Venera , Ziller Luca , Camin Federica 
Published: February 2017

RationaleNo study has investigated the variations in stable isotope ratios (SIRs) of bioelements within a Protected Designations of Origin (PDO) cheese and few studies have focused on the dietary background of animals. For traceability purposes, it is important to know how and whether these issues affect SIRs in a PDO cheese.MethodsThirty‐six Pecorino Siciliano cheese samples were collected in three east‐Sicilian areas in seasons in which green herbage was present or absent in the diet of the animals. The determination of C, N and S SIRs was performed using an isotope ratio mass spectrometer coupled with an elemental analyser. The H and O SIRs were measured using an isotope ratio mass spectrometer equipped with a thermal conversion elemental analyser pyrolysis unit.ResultsThe C, N, H, O and S SIRs measured in defatted cheeses were subjected to a multivariate stepwise discriminant analysis to verify if cheeses could be distinguished based on their geographical origin and on the animals' feeding regimen. Sulfur and nitrogen SIRs allowed the best discrimination among the three areas (97.2% correct classification of the cheeses). The discrimination of the feeding system, to check the presence or not of fresh forage in the diet of the animals, correctly classified 86.1% of the cheeses. The C and O SIRs were the most effective parameters.ConclusionsThis study demonstrates that the variability in C, H, O, N and S SIRs can allow discrimination between cheeses produced in a narrow geographical region within a PDO area. This may lead to the search for new tools in authentication studies such as the creation of specific isoscapes. Moreover, this study confirms that SIR determination can also discriminate cheeses obtained from animals fed in stalls from those produced when animals have access to green forage, with benefit in terms of environmental impact, animal welfare and product quality. Copyright © 2017 John Wiley & Sons, Ltd.
Full‐block multipliers for repeated, slope‐restricted scalar nonlinearities
Authors: Fetzer Matthias , Scherer Carsten W. 
Published: February 2017

SummaryThis paper provides a comprehensive treatment of full‐block multipliers within the integral quadratic constraints framework for stability analysis of feedback systems containing repeated, slope‐restricted scalar nonlinearities. We develop a novel stability result that offers more flexibility in its application because it allows for the inclusion of general Popov and Yakubovich criteria in combination with the well‐established Circle and Zames‐Falb stability tests within integral quadratic constraint theory. A particular focus lies on the formulation of stability criteria in terms of full‐block multipliers, some of which are new, and thus typically involve less conservatism than current methods. Furthermore, a new asymptotically exact parametrization of full‐block Zames‐Falb multipliers is given that allows to exploit the complete potential of this stability test. Copyright © 2017 John Wiley & Sons, Ltd.
Recent lab‐on‐chip developments for novel drug discovery
Authors: Khalid Nauman , Kobayashi Isao , Nakajima Mitsutoshi 
Published: February 2017

Microelectromechanical systems (MEMS) and micro total analysis systems (μTAS) revolutionized the biochemical and electronic industries, and this miniaturization process became a key driver for many markets. Now, it is a driving force for innovations in life sciences, diagnostics, analytical sciences, and chemistry, which are called ‘lab‐on‐a‐chip, (LOC)’ devices. The use of these devices allows the development of fast, portable, and easy‐to‐use systems with a high level of functional integration for applications such as point‐of‐care diagnostics, forensics, the analysis of biomolecules, environmental or food analysis, and drug development. In this review, we report on the latest developments in fabrication methods and production methodologies to tailor LOC devices. A brief overview of scale‐up strategies is also presented together with their potential applications in drug delivery and discovery. The impact of LOC devices on drug development and discovery has been extensively reviewed in the past. The current research focuses on fast and accurate detection of genomics, cell mutations and analysis, drug delivery, and discovery. The current research also differentiates the LOC devices into new terminology of microengineering, like organ‐on‐a‐chip, stem cells‐on‐a‐chip, human‐on‐a‐chip, and body‐on‐a‐chip. Key challenges will be the transfer of fabricated LOC devices from lab‐scale to industrial large‐scale production. Moreover, extensive toxicological studies are needed to justify the use of microfabricated drug delivery vehicles in biological systems. It will also be challenging to transfer the in vitro findings to suitable and promising in vivo models. WIREs Syst Biol Med 2017, 9:e1381. doi: 10.1002/wsbm.1381This article is categorized under:

Analytical and Computational Methods > Analytical Methods
Models of Systems Properties and Processes > Organ, Tissue, and Physiological Models
Bridging the training-practice gap in interprofessional student supervision
Authors: Martin Priya , Kumar Saravana , Abernathy LuJuana 
Published: February 2017

Background Workforce recruitment and retention issues are common in highly dispersed regions such as Queensland in Australia. Provision of student placements in these non-metropolitan areas is one way of promoting staff recruitment. However, healthcare professionals in these areas face a number of challenges in accessing training opportunities including student supervision training. Funding was made available to develop and run a series of targeted, evidence-based, interprofessional student supervision workshops in non-metropolitan Queensland.
Methods Workshop participants were health professionals from both public and private health service providers in Queensland. Using a pre-post design, anonymous data were collected through surveys administered before and after workshop participation. Descriptive statistics were used to analyze participant information. Free text responses were categorized using an iterative process to identify prevalent themes.
Results A total of 147 participants attended nine face-to-face workshops and provided data. Allied health participants represented 70% of the population, with the remainder largely from nursing, medicine and dentistry. There was a positive shift in self-reported level of confidence in student supervision following training. Of the participants 143 (97%) reported that they acquired new skills and knowledge from training. A number of enablers of and barriers to translation of learning to practice following interprofessional student supervision training were identified.
Conclusions Targeted interprofessional student supervision training is valuable and can increase participants’ self-reported level of confidence in student supervision. It is recommended that health organizations promote a culture of providing positive student placement experiences in order to maximize future workforce opportunities.
Immunodiagnosis of paramphistomosis using monoclonal antibody-based sandwich ELISA for detection ofParamphistomum gracilecirculating 16 kDa antigen
Authors: ANURACPREEDA PANAT , TEPSUPORNKUL KULLANID , CHAWENGKIRTTIKUL RUNGLAWAN 
Published: February 2017

SUMMARYIn this study, we have produced a monoclonal antibody (MoAb) against 16 kDa antigen ofParamphistomum gracile(16 kDaAgPg), and developed an accurate sandwich enzyme-linked immunosorbent assay (sandwich ELISA) for the detection of circulating 16 kDaAg in the serum and fecal samples from cattle naturally infected withP. gracile. MoAb 1D10 was immobilized on a microtitre plate, and the antigen in the samples was captured and detected with biotinylated rabbit anti-16 kDaAgPg antibody. The lower detection limit of sandwich ELISA was 3·5 pg mL−1, and no cross-reaction with other parasite antigens was evaluated. The reliability of the assay was examined using the serum and fecal samples from cattle naturally infected withP. gracile, Fasciola gigantica, Moniezia benedeni, Trichurissp.,Strongyloidessp., strongylids and non-infected animals. The sandwich ELISA showed the sensitivity, specificity and accuracy at 98·33, 100 and 99·55% (serum samples), and 96·67, 100 and 99·09% (fecal samples). Therefore, this detection method is a rapid and excellent potential assay for the accurate diagnosis of paramphistomosis.
A Descriptive Analysis of Tactical Casualty Care Interventions Performed by Law Enforcement Personnel in the State of Wisconsin, 2010-2015
Authors: Stiles Chad M. , Cook Christopher , Sztajnkrycer Matthew D. 
Published: February 2017

AbstractIntroductionBased upon military experience, law enforcement has developed guidelines for medical care during high-threat conditions. The purpose of the current study was to provide a descriptive analysis of reported outcomes of law enforcement medical interventions.MethodsThis was a descriptive analysis of a convenience sample of cases submitted to the Wisconsin Tactical Medicine Initiative (Wisconsin USA), after the provision of successful patient care, between January 2010 and December 2015. The study was reviewed by the Mayo Foundation Institutional Review Board (Rochester, Minnesota USA) and deemed exempt.ResultsNineteen agencies submitted information during the study period. Of the 56 episodes of care reported, four (7.1%) cases involved care provided to injured officers while 52 (92.9%) involved care to injured civilians, including suspects. In at least two cases, on-going threats existed during the provision of medical care to an injured civilian. Law enforcement rendered care prior to Emergency Medical Services (EMS) arrival in all but two cases.ConclusionsThe current case series demonstrates the life-saving potential for law enforcement personnel trained and equipped under current Tactical Combat Casualty Care (TCCC)/ Committee on Tactical Emergency Casualty Care (C-TECC) tactical casualty care guidelines. Although originally developed to save the lives of wounded combat personnel, in the civilian sector, the training appears more likely to save victims rather than law enforcement personnel.StilesCM,CookC,SztajnkrycerMD.A descriptive analysis of tactical casualty care interventions performed by law enforcement personnel in the State of Wisconsin, 2010-2015.Prehosp Disaster Med.2017;32(3):284–288.
Classifying news versus opinions in newspapers: Linguistic features for domain independence
Authors: KRÜGER K. R. , LUKOWIAK A. , SONNTAG J. , WARZECHA S. , STEDE M. 
Published: February 2017

AbstractNewspaper text can be broadly divided in the classes ‘opinion’ (editorials, commentary, letters to the editor) and ‘neutral’ (reports). We describe a classification system for performing this separation, which uses a set of linguistically motivated features. Working with various English newspaper corpora, we demonstrate that it significantly outperforms bag-of-lemma and PoS-tag models. We conclude that the linguistic features constitute the best method for achieving robustness against change of newspaper or domain.
Development of spinal deformities in the tight-skin mouse
Authors: Li Bing , Urban Jill PG , Yu Jing 
Published: February 2017

AbstractTight-skin (TSK) mice are commonly used as an animal model to study the pathogenesis of Marfan syndrome (MFS), but little is known of their skeletal phenotype and in particular of the development of the spinal deformities, common in MFS. Here we examined growth of the axial skeletons of TSK and wild-type(B6) mice during their period of rapid growth. The whole bodies of mice, 4–12 weeks of age, were scanned after sacrifice, by micro-computed tomography (microCT). We reconstructed three-dimensional models of the spine and ribs, and measured vertebral body heights and rib lengths using the Mac-based image-processing software “OsiriX”. Although the TSK mice were smaller than the B6 mice at 4 weeks, they experienced an early growth spurt and by 8 weeks the height, but not the width, of the vertebral body was significantly greater in the TSK mice than the B6 mice. Measurement of the angles of scoliotic and kyphotic curves post-mortem in the mice was problematic, hence we measured changes that develop in skeletal elements in these disorders. As a marker of kyphosis, we measured anterior wedging of the vertebral bodies; as a marker for scoliosis we measured asymmetries in rib length. We found, unlike in the B6 mice where the pattern was diffuse, wedging in TSK mice was directly related to spinal level and peaked steeply at the thoracolumbar junction. There was also significant asymmetry in length of the ribs in the TSK mice, but not in the B6 mice. The TSK mice thus appear to exhibit spinal deformities seen in MFS and could be a useful model for gaining understanding of the mechanisms of development of scoliosis and kyphosis in this disorder.
Limited options for low-global-warming-potential refrigerants
Authors: McLinden Mark O. , Brown J. Steven , Brignoli Riccardo , Kazakov Andrei F. , Domanski Piotr A. 
Published: February 2017

AbstractHydrofluorocarbons, currently used as refrigerants in air-conditioning systems, are potent greenhouse gases, and their contribution to climate change is projected to increase. Future use of the hydrofluorocarbons will be phased down and, thus replacement fluids must be found. Here we show that only a few pure fluids possess the combination of chemical, environmental, thermodynamic, and safety properties necessary for a refrigerant and that these fluids are at least slightly flammable. We search for replacements by applying screening criteria to a comprehensive chemical database. For the fluids passing the thermodynamic and environmental screens (critical temperature and global warming potential), we simulate performance in small air-conditioning systems, including optimization of the heat exchangers. We show that the efficiency-versus-capacity trade-off that exists in an ideal analysis disappears when a more realistic system is considered. The maximum efficiency occurs at a relatively high volumetric refrigeration capacity, but there are few fluids in this range.
Platelets prime hematopoietic–vascular niche to drive angiocrine-mediated liver regeneration
Authors: Shido Koji , Chavez Deebly , Cao Zhongwei , Ko Jane L , Rafii Shahin , Ding Bi-Sen 
Published: February 2017

AbstractIn mammals, the livers regenerate after chemical injury or resection of hepatic lobe by hepatectomy. How liver regeneration is initiated after mass loss remains to be defined. Here we report that following liver injury, activated platelets deploy SDF-1 and VEGF-A to stimulate CXCR7+ liver sinusoidal endothelial cell (LSEC) and VEGFR1+ myeloid cell, orchestrating hepatic regeneration. After carbon tetrachloride injection or hepatectomy, platelets and CD11b+VEGFR1+ myeloid cells were recruited to LSECs, and liver regeneration in both models was impaired in thrombopoietin-deficient (Thpo−/−) mice repressing production of circulating platelets. This impeded regeneration phenotype was recapitulated in mice with either conditional ablation of Cxcr7 in LSEC (Cxcr7iΔ/iΔ) or Vegfr1 in myeloid cell (Vegfr1lysM/lysM). Both Vegfr1lysM/lysM and Cxcr7iΔ/iΔ mice exhibited suppressed expression of hepatocyte growth factor and Wnt2, two crucial trophogenic angiocrine factors instigating hepatocyte propagation. Of note, administration of recombinant thrombopoietin restored the prohibited liver regeneration in the tested genetic models. As such, our data suggest that platelets and myeloid cells jointly activate the vascular niche to produce pro-regenerative endothelial paracrine/angiocrine factors. Modulating this ‘hematopoietic–vascular niche’ might help to develop regenerative therapy strategy for hepatic disorders.