bluuebunny/crossref_metadata_2025_split huggingface dataset:
SETS WITH EVEN PARTITION FUNCTIONS AND CYCLOTOMIC NUMBERS
Authors: BACCAR N. 
Published: March 2016

Let $P\in \mathbb{F}_{2}[z]$ be such that $P(0)=1$ and degree $(P)\geq 1$. Nicolas et al. [‘On the parity of additive representation functions’, J. Number Theory73 (1998), 292–317] proved that there exists a unique subset ${\mathcal{A}}={\mathcal{A}}(P)$ of $\mathbb{N}$ such that $\sum _{n\geq 0}p({\mathcal{A}},n)z^{n}\equiv P(z)~\text{mod}\,2$, where $p({\mathcal{A}},n)$ is the number of partitions of $n$ with parts in ${\mathcal{A}}$. Let $m$ be an odd positive integer and let ${\it\chi}({\mathcal{A}},.)$ be the characteristic function of the set ${\mathcal{A}}$. Finding the elements of the set ${\mathcal{A}}$ of the form $2^{k}m$, $k\geq 0$, is closely related to the $2$-adic integer $S({\mathcal{A}},m)={\it\chi}({\mathcal{A}},m)+2{\it\chi}({\mathcal{A}},2m)+4{\it\chi}({\mathcal{A}},4m)+\cdots =\sum _{k=0}^{\infty }2^{k}{\it\chi}({\mathcal{A}},2^{k}m)$, which has been shown to be an algebraic number. Let $G_{m}$ be the minimal polynomial of $S({\mathcal{A}},m)$. In precedent works there were treated the case $P$ irreducible of odd prime order $p$. In this setting, taking $p=1+ef$, where $f$ is the order of $2$ modulo $p$, explicit determinations of the coefficients of $G_{m}$ have been made for $e=2$ and 3. In this paper, we treat the case $e=4$ and use the cyclotomic numbers to make explicit $G_{m}$.
Choralities
Authors: CONNOR STEVEN 
Published: March 2016

AbstractThe voice has often been identified with the assertion of idiosyncrasy or exception (The Chanting Crowd: ‘We are all individuals!’ An Individual: ‘I'm not.’ Monty Python,The Life of Brian). This article explores why humans (though not uniquely them) feel urged to merge and magnify the individual voice through assimilating it to the voices of others. What are the powers, menaces, and satisfactions of these singular–plural megavoices, in choirs, collective chants, and other forms of what may be calledchorality, that have become more familiar than ever in the mass spectacles (‘audicles’?) of sport, entertainment, and politics? I suggest that the chorus represents the challenge of the inchoate, in that it is the making manifest of what menaces music, the matter that must be made into form, a reservoir of unschooled energy that must be converted to information. I suggest that there may be an implicit relation between the individual voice and the collective voice it may seem to convoke, such that every individual vocality has a connection to a phantasmal chorality. Finally, I consider the political force of chorality, and the fantasy focused on and through the collective voice, and what this means in a world that seems to have moved from the dominion of the mass to that of the multitude.
‘My Tongue Gets t-t-t-’: Words, Sense, and Vocal Presence in Van Morrison'sIt's Too Late to Stop Now
Authors: ELLIOTT RICHARD 
Published: March 2016

AbstractVan Morrison's live version of his song ‘Cyprus Avenue’ on the 1974 albumIt's Too Late to Stop Nowprovides an example of the authority of the singer's voice and of how it leads and demands submission from musicians, songs, and audience. Morrison's voice constantly suggests that it is reflecting important experience and can be understood both as an attempt to capture something and as a post-hoc witnessing or testimony. Through the example of Morrison's work, and ofIt's Too Late to Stop Nowin particular, this article explores the location of the voice in terms of the body and of particular places and histories. It then proceeds to a reflection on the relationship between the performing voice as producer of sound, noise, and music and the poetic voice that provides the words and visions upon which the performing voice goes to work. It concludes by focusing on a moment within ‘Cyprus Avenue’ where Morrison performs the act of being tongue-tied, discussing this as an example of ‘aesthetic stutter’. Throughout, attention is also paid to how other voices (particularly those of rock critics) connect to Morrison's voice by attempting to describe it, re-perform it, or explain it.
Validity Evidence based on Internal Structure of Scores of the Emotional Quotient-Inventory: Youth Version Short (EQ-i: YV-S) in a Spanish Sample
Authors: Esnaola Igor , Freeman John , Sarasa Marta , Fernández-Zabala Arantza , Axpe Inge 
Published: March 2016

AbstractThe purpose of this study was to analyze the reliability and validity evidence of scores on the Spanish version of EQ-i: YV-S in Spanish adolescents. The total sample was comprised of 508 participants from Grades 7 to 12, 241 males (47.4%) and 267 females (52.6%), each of whom completed the questionnaires on two separate occasions. Three [intrapersonal (α = .83, CR = .86, and McDonald Omega = .86), stress management (α = .83, CR = .86, and McDonald Omega = .85) and adaptability (α = .82, CR = .85, and McDonald Omega = .85)] of the four scales had acceptable internal consistency. Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were used with FACTOR and EQS version 6.1 software to examine validity evidence based on internal structure drawn from the scores on the EQ-i: YV-S, supporting the multidimensionality of the questionnaire. Three models were tested; the best fit to the data was the hierarchical model (S-Bχ2/ df = 2.11, CFI = .93 and RMSEA = .047), which hypothesized that the four specific factors (interpersonal, intrapersonal, stress management, and adaptability) were explained with a second-order factor, Emotional-Social-Intelligence (ESI). Finally, significant positive correlations were found between general self-concept and EQ-i: YV-S [interpersonal (r = .153, p < .001), intrapersonal (r = .235, p < .001), stress management (r = .145, p < .001), adaptability (r = .311, p < .001) and ESI (r = .360, p < .001)]; ESI showed significant direct power prediction of the general self-concept (.52) as demonstrated through structural equation modeling.
Erleben und Unterstützungsbedarf von Eltern hospitalisierter Kinder mit Mehrfachbehinderung
Authors: Seliner Brigitte , Latal Bea , Spirig Rebecca 
Published: March 2016

Zusammenfassung. Hintergrund: Die Hospitalisation eines Kindes mit Mehrfachbehinderung belastet Eltern, da sie auch im Spital viele Betreuungsaufgaben übernehmen müssen. Leider fehlt systematisches Wissen über das elterliche Erleben in dieser Situation und deren Unterstützungsbedarf. Fragestellung: Wie erfahren Eltern die Hospitalisation, und welchen Unterstützungsbedarf geben sie für diesen Zeitraum an? Methode: An dieser qualitativen Untersuchung partizipierten 26 Elternteile (24 Mütter, zwei Väter) von 24 mehrfachbehinderten Kindern. Zwischen dem 1. Januar 2011 und dem 1. September 2013 wurden mit ihnen in einer universitären Kinderklinik halbstrukturierte Interviews geführt. Die strukturierende qualitative Inhaltsanalyse leitete die Analyse. Ergebnisse: Für die Eltern stand die «Sorge um das Wohl des Kindes» im Zentrum. Die Einschätzung des kindlichen Wohls prägte das Ausmaß der «Arbeit der Eltern» und definierte den elterlichen «Unterstützungsbedarf» nach «Information und Schulung erhalten», «Bekannt sein und Kontinuität erfahren», «Ernst genommen werden und Mitsein erfahren», «Begleitet werden von erfahrenen Pflegenden» und «Entlastet und organisatorisch unterstützt werden». Schlussfolgerung: Die Eltern leisten viel Arbeit, um das Wohl des hospitalisierten, mehrfachbehinderten Kindes sicherzustellen. Pflegefachpersonen können zur Entlastung dieser Eltern beitragen, indem sie deren Vertrauen in das Wohl des Kindes im Spital stärken. Dies gelingt, wenn Kontinuität und Kompetenz vonseiten der Pflegefachpersonen sichergestellt sind, wie es beispielsweise Pflegende mit einem Advanced-Practice-Hintergrund ermöglichen.
Multifrequency excitation of a clamped–clamped microbeam: Analytical and experimental investigation
Authors: Jaber Nizar , Ramini Abdallah , Younis Mohammad I. 
Published: March 2016

AbstractUsing partial electrodes and a multifrequency electrical source, we present a large-bandwidth, large-amplitude clamped–clamped microbeam resonator excited near the higher order modes of vibration. We analytically and experimentally investigate the nonlinear dynamics of the microbeam under a two-source harmonic excitation. The first-frequency source is swept around the first three modes of vibration, whereas the second source frequency remains fixed. New additive and subtractive resonances are demonstrated. We illustrated that by properly tuning the frequency and amplitude of the excitation force, the frequency bandwidth of the resonator is controlled. The microbeam is fabricated using polyimide as a structural layer coated with nickel from the top and chromium and gold layers from the bottom. Using the Galerkin method, a reduced order model is derived to simulate the static and dynamic response of the device. A good agreement between the theoretical and experimental data are reported.
Magneto-optical imaging of thin magnetic films using spins in diamond
Authors: Simpson David A. , Tetienne Jean-Philippe , McCoey Julia M. , Ganesan Kumaravelu , Hall Liam T. , Petrou Steven , Scholten Robert E. , Hollenberg Lloyd C. L. 
Published: March 2016

AbstractImaging the fields of magnetic materials provides crucial insight into the physical and chemical processes surrounding magnetism and has been a key ingredient in the spectacular development of magnetic data storage. Existing approaches using the magneto-optic Kerr effect, x-ray and electron microscopy have limitations that constrain further development and there is increasing demand for imaging and characterisation of magnetic phenomena in real time with high spatial resolution. Here we show how the magneto-optical response of an array of negatively-charged nitrogen-vacancy spins in diamond can be used to image and map the sub-micron stray magnetic field patterns from thin ferromagnetic films. Using optically detected magnetic resonance, we demonstrate wide-field magnetic imaging over 100 × 100 μm2 with sub-micron spatial resolution at video frame rates, under ambient conditions. We demonstrate an all-optical spin relaxation contrast imaging approach which can image magnetic structures in the absence of an applied microwave field. Straightforward extensions promise imaging with sub-μT sensitivity and sub-optical spatial and millisecond temporal resolution. This work establishes practical diamond-based wide-field microscopy for rapid high-sensitivity characterisation and imaging of magnetic samples, with the capability for investigating magnetic phenomena such as domain wall and skyrmion dynamics and the spin Hall effect in metals.
Identification of novel RNA secondary structures within the hepatitis C virus genome reveals a cooperative involvement in genome packaging
Authors: Stewart H. , Bingham R.J. , White S. J. , Dykeman E. C. , Zothner C. , Tuplin A. K. , Stockley P. G. , Twarock R. , Harris M. 
Published: March 2016

AbstractThe specific packaging of the hepatitis C virus (HCV) genome is hypothesised to be driven by Core-RNA interactions. To identify the regions of the viral genome involved in this process, we used SELEX (systematic evolution of ligands by exponential enrichment) to identify RNA aptamers which bind specifically to Core in vitro. Comparison of these aptamers to multiple HCV genomes revealed the presence of a conserved terminal loop motif within short RNA stem-loop structures. We postulated that interactions of these motifs, as well as sub-motifs which were present in HCV genomes at statistically significant levels, with the Core protein may drive virion assembly. We mutated 8 of these predicted motifs within the HCV infectious molecular clone JFH-1, thereby producing a range of mutant viruses predicted to possess altered RNA secondary structures. RNA replication and viral titre were unaltered in viruses possessing only one mutated structure. However, infectivity titres were decreased in viruses possessing a higher number of mutated regions. This work thus identified multiple novel RNA motifs which appear to contribute to genome packaging. We suggest that these structures act as cooperative packaging signals to drive specific RNA encapsidation during HCV assembly.
Intraguild predation between Amblyseius swirskii and two native Chinese predatory mite species and their development on intraguild prey
Authors: Guo Yingwei , Lv Jiale , Jiang Xiaohuan , Wang Boming , Gao Yulin , Wang Endong , Xu Xuenong 
Published: March 2016

AbstractAmblyseius swirskii, native to the east and southeast Mediterranean region, is a successful biological control agent of whiteflies. In this study, we investigated intraguild predations (IGP) between each stage of A. swirskii and each stage of two Phytoseiid species that occur in China, Amblyseius orientalis and Neoseiulus californicus. When there was no whitefly egg provided as the extraguild prey, IGP between A. swirskii and A. orientalis, and between A. swirskii and N. californicus, was observed in 10 and 20 out of 35 combinations, respectively. When IGP was observed, A. swirskii was the intraguild predator in 70% and 65% cases of A. orientalis and N. californicus predation, respectively. These results suggest that A. swirskii is a more aggressive intraguild predator compared to either A. orientalis or N. californicus. When whitefly eggs were provided as the extraguild prey, IGP between A. swirskii and N. californicus decreased greatly, but no significant decrease of IGP was observed between A. swirskii and A. orientalis. Amblyseius swirskii was able to complete development on both heterospecific predatory mites, and both heterospecific predatory mites completed their development on A. swirskii. Possible impacts that A. swirskii may have on local predatory mite populations in China are discussed.
Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer
Authors: Guo Xiaojia , Hollander Lindsay , MacPherson Douglas , Wang Ling , Velazquez Heino , Chang John , Safirstein Robert , Cha Charles , Gorelick Fred , Desir Gary V. 
Published: March 2016

AbstractAn essential feature of cancer is dysregulation of cell senescence and death. Renalase, a recently discovered secreted flavoprotein, provides cytoprotection against ischemic and toxic cellular injury by signaling through the PI3K-AKT and MAPK pathways. Here we show that renalase expression is increased in pancreatic cancer tissue and that it functions as a growth factor. In a cohort of patients with pancreatic ductal adenocarcinoma, overall survival was inversely correlated with renalase expression in the tumor mass, suggesting a pathogenic role for renalase. Inhibition of renalase signaling using siRNA or inhibitory anti-renalase antibodies decreased the viability of cultured pancreatic ductal adenocarcinoma cells. In two xenograft mouse models, either the renalase monoclonal antibody m28-RNLS or shRNA knockdown of renalase inhibited pancreatic ductal adenocarcinoma growth. Inhibition of renalase caused tumor cell apoptosis and cell cycle arrest. These results reveal a previously unrecognized role for the renalase in cancer: its expression may serve as a prognostic maker and its inhibition may provide an attractive therapeutic target in pancreatic cancer.
hnRNPK inhibits GSK3β Ser9 phosphorylation, thereby stabilizing c-FLIP and contributes to TRAIL resistance in H1299 lung adenocarcinoma cells
Authors: Gao Xuejuan , Feng Junxia , He Yujiao , Xu Fengmei , Fan Xiaoqin , Huang Wensi , Xiong Haiting , Liu Qiuyu , Liu Wanting , Liu Xiaohui , Sun Xuesong , He Qing-Yu , Zhang Qihao , Liu Langxia 
Published: March 2016

Abstractc-FLIP (cellular FLICE-inhibitory protein) is the pivotal regulator of TRAIL resistance in cancer cells, It is a short-lived protein degraded through the ubiquitin/proteasome pathway. The discovery of factors and mechanisms regulating its protein stability is important for the comprehension of TRAIL resistance by tumor cells. In this study, we show that, when H1299 lung adenocarcinoma cells are treated with TRAIL, hnRNPK is translocated from nucleus to cytoplasm where it interacts and co-localizes with GSK3β. We find that hnRNPK is able to inhibit the Ser9 phosphorylation of GSK3β by PKC. This has the effect of activating GSK3β and thereby stabilizing c-FLIP protein which contributes to the resistance to TRAIL in H1299 cells. Our immunohistochemical analysis using tissue microarray provides the clinical evidence of this finding by establishing a negative correlation between the level of hnRNPK expression and the Ser9 phosphorylation of GSK3β in both lung adenocarcinoma tissues and normal tissues. Moreover, in all cancer tissues examined, hnRNPK was found in the cytoplasm whereas it is exclusively nuclear in the normal tissues. Our study sheds new insights on the molecular mechanisms governing the resistance to TRAIL in tumor cells, and provides new clues for the combinatorial chemotherapeutic interventions with TRAIL.
Effects of Systemically Administered Hydrocortisone on the Human Immunome
Authors: Olnes Matthew J. , Kotliarov Yuri , Biancotto Angélique , Cheung Foo , Chen Jinguo , Shi Rongye , Zhou Huizhi , Wang Ena , Tsang John S. , Nussenblatt Robert ,   The CHI Consortium, Dickler Howard B. , Hourigan Christopher S. , Marincola Francesco M. , McCoy J. Phillip , Perl Shira , Schum Paula , Schwartzberg Pamela L. , Trinchieri Giorgio , Valdez Janet , Young Neal S. 
Published: March 2016

AbstractCorticosteroids have been used for decades to modulate inflammation therapeutically, yet there is a paucity of data on their effects in humans. We examined the changes in cellular and molecular immune system parameters, or “immunome”, in healthy humans after systemic corticosteroid administration. We used multiplexed techniques to query the immunome in 20 volunteers at baseline, and after intravenous hydrocortisone (HC) administered at moderate (250 mg) and low (50 mg) doses, to provide insight into how corticosteroids exert their effects. We performed comprehensive phenotyping of 120 lymphocyte subsets by high dimensional flow cytometry, and observed a decline in circulating specific B and T cell subsets, which reached their nadir 4–8 hours after administration of HC. However, B and T cells rebounded above baseline 24 hours after HC infusion, while NK cell numbers remained stable. Whole transcriptome profiling revealed down regulation of NF-κB signaling, apoptosis, and cell death signaling transcripts that preceded lymphocyte population changes, with activation of NK cell and glucocorticoid receptor signaling transcripts. Our study is the first to systematically characterize the effects of corticosteroids on the human immunome, and we demonstrate that HC exerts differential effects on B and T lymphocytes and natural killer cells in humans.
Bio-inspired, Moisture-Powered Hybrid Carbon Nanotube Yarn Muscles
Authors: Kim Shi Hyeong , Kwon Cheong Hoon , Park Karam , Mun Tae Jin , Lepró Xavier , Baughman Ray H. , Spinks Geoffrey M. , Kim Seon Jeong 
Published: March 2016

AbstractHygromorph artificial muscles are attractive as self-powered actuators driven by moisture from the ambient environment. Previously reported hygromorph muscles have been largely limited to bending or torsional motions or as tensile actuators with low work and energy densities. Herein, we developed a hybrid yarn artificial muscle with a unique coiled and wrinkled structure, which can be actuated by either changing relative humidity or contact with water. The muscle provides a large tensile stroke (up to 78%) and a high maximum gravimetric work capacity during contraction (2.17 kJ kg−1), which is over 50 times that of the same weight human muscle and 5.5 times higher than for the same weight spider silk, which is the previous record holder for a moisture driven muscle. We demonstrate an automatic ventilation system that is operated by the tensile actuation of the hybrid muscles caused by dew condensing on the hybrid yarn. This self-powered humidity-controlled ventilation system could be adapted to automatically control the desired relative humidity of an enclosed space.
Influence of an embedded quantum dot on the Josephson effect in the topological superconducting junction with Majorana doublets
Authors: Gong Wei-Jiang , Gao Zhen , Shan Wan-Fei , Yi Guang-Yu 
Published: March 2016

AbstractOne Majorana doublet can be realized at each end of the time-reversal-invariant Majorana nanowires. We investigate the Josephson effect in the Majorana-doublet-presented junction modified by different inter-doublet coupling manners. It is found that when the Majorana doublets couple indirectly via a non-magnetic quantum dot, only the normal Josephson effect occurs and the fermion parity in the system just affects the current direction and amplitude. However, one magnetic field applied on the dot can induce the fractional Josephson effect in the odd-parity case. Next if the direct and indirect couplings between the Majorana doublets coexist, no fractional Josephson effect takes place, regardless of the presence of magnetic field. Instead, there almost appears the π-period-like current in some special cases. All the results are clarified by analyzing the influence of the fermion occupation in the quantum dot on the parity conservation in the whole system. We ascertain that this work will be helpful for describing the dot-assisted Josephson effect between the Majorana doublets.
Using AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size
Authors: Hagg Adam , Colgan Timothy D. , Thomson Rachel E. , Qian Hongwei , Lynch Gordon S. , Gregorevic Paul 
Published: March 2016

AbstractAnabolic β2-adrenoceptor (β2-AR) agonists have been proposed as therapeutics for treating muscle wasting but concerns regarding possible off-target effects have hampered their use. We investigated whether β2-AR-mediated signalling could be modulated in skeletal muscleviagene delivery to the target tissue, thereby avoiding the risks of β2-AR agonists. In mice, intramuscular administration of a recombinant adeno-associated virus-based vector (rAAV vector) expressing the β2-AR increased muscle mass by >20% within 4 weeks. This hypertrophic response was comparable to that of 4 weeks’ treatment with the β2-AR agonist formoterol and was not ablated by mTOR inhibition. Increasing expression of inhibitory (Gαi2) and stimulatory (GαsL) G-protein subunits produced minor atrophic and hypertrophic changes in muscle mass, respectively. Furthermore, Gαi2 over-expression prevented AAV:β2-AR mediated hypertrophy. Introduction of the non-muscle Gαs isoform, GαsXL elicited hypertrophy comparable to that achieved by AAV:β2-AR. Moreover, GαsXL gene delivery was found to be capable of inducing hypertrophy in the muscles of mice lacking functional β1- and β2-ARs. These findings demonstrate that gene therapy-based interventions targeting the β2-AR pathway can promote skeletal muscle hypertrophy independent of ligand administration and highlight novel methods for potentially modulating muscle mass in settings of disease.