bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magneto-active substrates for local mechanical stimulation of living cells
Authors: Bidan Cécile M. , Fratzl Mario , Coullomb Alexis , Moreau Philippe , Lombard Alain H. , Wang Irène , Balland Martial , Boudou Thomas , Dempsey Nora M. , Devillers Thibaut , Dupont Aurélie 
Published: January 2018

AbstractCells are able to sense and react to their physical environment by translating a mechanical cue into an intracellular biochemical signal that triggers biological and mechanical responses. This process, called mechanotransduction, controls essential cellular functions such as proliferation and migration. The cellular response to an external mechanical stimulation has been investigated with various static and dynamic systems, so far limited to global deformations or to local stimulation through discrete substrates. To apply local and dynamic mechanical constraints at the single cell scale through a continuous surface, we have developed and modelled magneto-active substrates made of magnetic micro-pillars embedded in an elastomer. Constrained and unconstrained substrates are analysed to map surface stress resulting from the magnetic actuation of the micro-pillars and the adherent cells. These substrates have a rigidity in the range of cell matrices, and the magnetic micro-pillars generate local forces in the range of cellular forces, both in traction and compression. As an application, we followed the protrusive activity of cells subjected to dynamic stimulations. Our magneto-active substrates thus represent a new tool to study mechanotransduction in single cells, and complement existing techniques by exerting a local and dynamic stimulation, traction and compression, through a continuous soft substrate.
On terahertz pulsed broadband Gauss-Bessel beam free-space propagation
Authors: Kulya Maksim S. , Semenova Varvara A. , Bespalov Victor G. , Petrov Nikolay V. 
Published: January 2018

AbstractTerahertz pulse time-domain holography is the ultimate technique allowing the evaluating a propagation of pulse broadband terahertz wavefronts and analyze their spatial, temporal and spectral evolution. We have numerically analyzed pulsed broadband terahertz Gauss-Bessel beam’s both spatio-temporal and spatio-spectral evolution in the non-paraxial approach. We have characterized two-dimensional spatio-temporal beam behavior and demonstrated all stages of pulse reshaping during the propagation, including X-shape pulse forming. The reshaping is also illustrated by the energy transfer dynamics, where the pulse energy flows from leading edge to trailing edge. This behavior illustrates strong spatio-temporal coupling effect when spatio-temporal distribution of Bessel beam’s wavefront depends on propagation distance. The spatio-temporal and spatio-spectral profiles for different spectral components clearly illustrate the model where the Bessel beam’s wavefront at the exit from the axicon can be divided into radial segments for which the wave vectors intersect. Phase velocity via propagation distance is estimated and compared with existing experimantal results. Results of the phase velocity calculation depend strongly on distance increment value, thus demonstrating superluminal or subluminal behavior.
Nonsymmorphic symmetry protected node-line semimetal in the trigonal YH3
Authors: Shao Dexi , Chen Tong , Gu Qinyan , Guo Zhaopeng , Lu Pengchao , Sun Jian , Sheng Li , Xing Dingyu 
Published: January 2018

AbstractUsing ab initio calculations based on density-functional theory and effective model analysis, we propose that the trigonal YH3 (Space Group: P$$\bar{{\bf{3}}}$$

3
¯

c1) at ambient pressure is a node-line semimetal when spin-orbit coupling (SOC) is ignored. This trigonal YH3 has very clean electronic structure near Fermi level and its nodal lines locate very closely to the Fermi energy, which makes it a perfect system for model analysis. Symmetry analysis shows that the nodal ring in this compound is protected by the glide-plane symmetry, where the band inversion of |Y+, d
xz
〉 and |H1−, s〉 orbits at Γ point is responsible for the formation of the nodal lines. When SOC is included, the line nodes are prohibited by the glide-plane symmetry, and a small gap (≈5 meV) appears, which leads YH3 to be a strong topological insulator with Z2 indices (1,000). Thus the glide-plane symmetry plays an opposite role in the formation of the nodal lines in cases without and with SOC. As the SOC-induced gap is so small that can be neglected, this P$$\bar{{\bf{3}}}$$

3
¯

c1 YH3 may be a good candidate for experimental explorations on the fundamental physics of topological node-line semimetals. We find the surface states of this P$$\bar{{\bf{3}}}$$

3
¯

c1 phase are somehow unique and may be helpful to identify the real ground state of YH3 in the experiment.
Electrochemical Evaluation and Phase-related Impedance Studies on Silicon–Few Layer Graphene (FLG) Composite Electrode Systems
Authors: Huang Qianye , Loveridge Melanie J. , Genieser Ronny , Lain Michael J. , Bhagat Rohit 
Published: January 2018

AbstractSilicon-Few Layer Graphene (Si-FLG) composite electrodes are investigated using a scalable electrode manufacturing method. A comprehensive study on the electrochemical performance and the impedance response is measured using electrochemical impedance spectroscopy. The study demonstrates that the incorporation of few-layer graphene (FLG) results in significant improvement in terms of cyclability, electrode resistance and diffusion properties. Additionally, the diffusion impedance responses that occur during the phase changes in silicon is elucidated through Staircase Potentio Electrochemical Impedance Spectroscopy (SPEIS): a more comprehensive and straightforward approach than previous state-of-charge based diffusion studies.
Chitin digestibility is dependent on feeding behaviors, which determine acidic chitinase mRNA levels in mammalian and poultry stomachs
Authors: Tabata Eri , Kashimura Akinori , Kikuchi Azusa , Masuda Hiromasa , Miyahara Ryo , Hiruma Yusuke , Wakita Satoshi , Ohno Misa , Sakaguchi Masayoshi , Sugahara Yasusato , Matoska Vaclav , Bauer Peter O. , Oyama Fumitaka 
Published: January 2018

AbstractChitin, a polymer of N-acetyl-D-glucosamine (GlcNAc), functions as a major structural component in chitin-containing organism including crustaceans, insects and fungi. Recently, we reported that acidic chitinase (Chia) is highly expressed in mouse, chicken and pig stomach tissues and that it can digest chitin in the respective gastrointestinal tracts (GIT). In this study, we focus on major livestock and domestic animals and show that the levels of Chia mRNA in their stomach tissues are governed by the feeding behavior. Chia mRNA levels were significantly lower in the bovine (herbivores) and dog (carnivores) stomach than those in mouse, pig and chicken (omnivores). Consistent with the mRNA levels, Chia protein was very low in bovine stomach. In addition, the chitinolytic activity of E. coli-expressed bovine and dog Chia enzymes were moderately but significantly lower compared with those of the omnivorous Chia enzymes. Recombinant bovine and dog Chia enzymes can degrade chitin substrates under the artificial GIT conditions. Furthermore, genomes of some herbivorous animals such as rabbit and guinea pig do not contain functional Chia genes. These results indicate that feeding behavior affects Chia expression levels as well as chitinolytic activity of the enzyme, and determines chitin digestibility in the particular animals.
The Sloan Digital Sky Survey Quasar Catalog: Fourteenth data release
Authors: Pâris Isabelle , Petitjean Patrick , Aubourg Éric , Myers Adam D. , Streblyanska Alina , Lyke Brad W. , Anderson Scott F. , Armengaud Éric , Bautista Julian , Blanton Michael R. , Blomqvist Michael , Brinkmann Jonathan , Brownstein Joel R. , Brandt William Nielsen , Burtin Étienne , Dawson Kyle , de la Torre Sylvain , Georgakakis Antonis , Gil-Marín Héctor , Green Paul J. , Hall Patrick B. , Kneib Jean-Paul , LaMassa Stephanie M. , Le Goff Jean-Marc , MacLeod Chelsea , Mariappan Vivek , McGreer Ian D. , Merloni Andrea , Noterdaeme Pasquier , Palanque-Delabrouille Nathalie , Percival Will J. , Ross Ashley J. , Rossi Graziano , Schneider Donald P. , Seo Hee-Jong , Tojeiro Rita , Weaver Benjamin A. , Weijmans Anne-Marie , Yèche Christophe , Zarrouk Pauline , Zhao Gong-Bo 
Published: January 2018

We present the data release 14 Quasar catalog (DR14Q) from the extended Baryon Oscillation Spectroscopic Survey (eBOSS) of the Sloan Digital Sky Survey IV (SDSS-IV). This catalog includes all SDSS-IV/eBOSS objects that were spectroscopically targeted as quasar candidates and that are confirmed as quasars via a new automated procedure combined with a partial visual inspection of spectra, have luminosities Mi [z = 2] < −20.5 (in a Λ CDM cosmology with H0 = 70 km s−1 Mpc−1, Ω M =0.3, and Ω Λ = 0.7), and either display at least one emission line with a full width at half maximum larger than 500 km s−1 or, if not, have interesting/complex absorption features. The catalog also includes previously spectroscopically-confirmed quasars from SDSS-I, II, and III. The catalog contains 526 356 quasars (144 046 are new discoveries since the beginning of SDSS-IV) detected over 9376 deg2 (2044 deg2 having new spectroscopic data available) with robust identification and redshift measured by a combination of principal component eigenspectra. The catalog is estimated to have about 0.5% contamination. Redshifts are provided for the Mg II emission line. The catalog identifies 21 877 broad absorption line quasars and lists their characteristics. For each object, the catalog presents five-band (u, g, r, i, z) CCD-based photometry with typical accuracy of 0.03 mag. The catalog also contains X-ray, ultraviolet, near-infrared, and radio emission properties of the quasars, when available, from other large-area surveys. The calibrated digital spectra, covering the wavelength region 3610–10 140 Å at a spectral resolution in the range 1300 < R < 2500, can be retrieved from the SDSS Science Archiver Server.
Reha in der Alterstraumatologie
Authors: Greitemann Bernhard 
Published: January 2018

ZusammenfassungDas steigende Lebensalter der Bevölkerung und der damit verbundene hohe Anteil älterer Menschen führen zwangsläufig auch zu einer erhöhten Anzahl von Traumata im höheren Alter. Bedingt ist dies durch ein Zusammenwirken von nachlassender Kraft und Koordination, begleitet von Störungen des Gleichgewichtssinns, der Sehfähigkeit und einer in aller Regel vorhandenen Multimorbidität, die zum sog. Frailty-Syndrom führt, d. h. allen Zeichen der Gebrechlichkeit. Auch die bei älteren Patienten oft anzutreffende Multimedikation mit fatalen Nebenwirkungen auf Koordination und Gleichgewicht sowie Kreislauf verstärken dies mit daraus resultierender deutlich erhöhter Sturzgefahr. Klassische im Alter vorkommende Frakturen sind insbesondere hüftgelenksnahe Frakturen (im Speziellen Azetabulum- und Femurfrakturen, Frakturen am Humerus bzw. Handgelenk, aber auch scheinbar banale Umknicktraumata mit schweren Luxationsfrakturen im Bereich des Sprunggelenks). Nicht unerwähnt bleiben soll der hohe Anteil von Betroffenen von Insuffizienzfrakturen bei vorbestehender Osteoporose, dann meist im Bereich der Wirbelsäule bzw. des Beckens. All diese Patienten bedürfen einer speziellen multi- und interdisziplinären rehabilitativen Fürsorge. Es ist eine intensive Kooperation zwischen Operateur und orthopädisch-traumatologisch sowie geriatrisch erfahrenem Rehabilitationsspezialisten erforderlich, um diese Patienten suffizient betreuen zu können.
Kraftfahreignung nach Schlaganfall
Authors: Marx Peter 
Published: January 2018

ZusammenfassungKraftfahreignung nach einem zerebrovaskulären Ereignis kann erst nach erfolgreicher Therapie und abhängig von den besonderen Umständen des
Einzelfalles attestiert werden. Die dem behandelnden Arzt obliegende Sicherheitsaufklärung erfordert ebenso, wie die Begutachtung,
Kenntnisse der rechtlichen Gegebenheiten, die in Fahrerlaubnisverordnung bzw. den Begutachtungsleitlinien zur Kraftfahrereignung
niedergelegt sind. Dem Arzt obliegt die Aufgabe, eventuelle Beeinträchtigungen der körperlichen und geistigen Leistungsfähigkeit für das
Führen eines Kraftfahrzeuges zu erkennen und zu bewerten, das Gefährdungspotential durch plötzliches Versagen der körperlich-geistigen
(psychischen) Leistungsfähigkeit zu prognostizieren und dabei auch eventuelle sicherheitswidrige Einstellungen, mangelnde Einsichtsfähigkeit
oder Persönlichkeitsmängel zu berücksichtigen, die ein regelkonformes und sicherheitsgerechtes Verhalten nicht gewährleisten.
Körperlich-geistige Leistungsfähigkeitseinschränkungen nach Schlaganfällen können oft durch Auflagen und Beschränkungen kompensiert werden.
Besonders schwierig sind Aussagen über die Wahrscheinlichkeit eines plötzlichen Kontrollverlust und die dadurch bedingte Verkehrsgefährdung
durch Schlaganfallrezidive. In Anlehnung an die Risk-of-Harm-Formula der Canadian Cardiovascular Society werden Einschätzungsmodelle
diskutiert, die zur Orientierung dienen können.
Characterization of medium-chain-length polyhydroxyalkanoate biosynthesis by Pseudomonas mosselii TO7 using crude glycerol
Authors: Liu Ming-Hsu , Chen Yi-Jr , Lee Chia-Yin 
Published: January 2018

Abstract
Polyhydroxyalkanoates (PHAs) are biopolyesters produced by microorganisms that are environmentally friendly. PHAs can be used to replace traditional plastic to reduce environmental pollution in various fields. PHA production costs are high because PHA must be produced from a carbon substrate. The purpose of this study was to find the strain that can used the BDF by-product as the sole carbon source to produce high amounts of medium-chain-length PHA. Three isolates were evaluated for potential PHA production by using biodiesel-derived crude glycerol as the sole carbon source. Among them, Pseudomonas mosselii TO7 yielded high PHA content. The PHA produced from P. mosselii TO7 were medium-chain-length-PHAs. The PHA content of 48% cell dry weight in 48 h with a maximum PHA productivity of 13.16 mg PHAs L−1 h−1. The narrow polydispersity index value of 1.3 reflected the homogeneity of the polymer chain, which was conducive to industrial applications.
The second Herschel–ATLAS Data Release – III. Optical and near-infrared counterparts in the North Galactic Plane field
Authors: Furlanetto C , Dye S , Bourne N , Maddox S , Dunne L , Eales S , Valiante E , Smith M W , Smith D J B , Ivison R J , Ibar E 
Published: January 2018

Abstract
This paper forms part of the second major public data release of the Herschel Astrophysical Terahertz Large Area Survey (H-ATLAS). In this work, we describe the identification of optical and near-infrared counterparts to the submillimetre detected sources in the 177 deg2 North Galactic Plane (NGP) field. We used the likelihood ratio method to identify counterparts in the Sloan Digital Sky Survey and in the United Kingdom InfraRed Telescope Imaging Deep Sky Survey within a search radius of 10 arcsec of the H-ATLAS sources with a 4σ detection at 250 μm. We obtained reliable (R ≥ 0.8) optical counterparts with r &lt; 22.4 for 42 429 H-ATLAS sources (37.8 per cent), with an estimated completeness of 71.7 per cent and a false identification rate of 4.7 per cent. We also identified counterparts in the near-infrared using deeper K-band data which covers a smaller ∼25 deg2. We found reliable near-infrared counterparts to 61.8 per cent of the 250-μm-selected sources within that area. We assessed the performance of the likelihood ratio method to identify optical and near-infrared counterparts taking into account the depth and area of both input catalogues. Using catalogues with the same surface density of objects in the overlapping ∼25 deg2 area, we obtained that the reliable fraction in the near-infrared (54.8 per cent) is significantly higher than in the optical (36.4 per cent). Finally, using deep radio data which covers a small region of the NGP field, we found that 80–90 per cent of our reliable identifications are correct.
All in The Name of Vanity
Authors: Li Yan , Spooner Linda M. , Abraham George M. 
Published: January 2018

Abstract
We report a case of refractory skin abscesses caused by Mycobacterium abscessus resulting from cosmetic surgery. A 25-year-old woman developed recurrent cutaneous infection caused by M. abscessus after multiple cosmetic surgeries in the Dominican Republic. Despite of the removal of infected implants, she failed a 20-month treatment with azithromycin, cefoxitin, and amikacin. The patient presented to our institution 28 months after the initial surgeries and approximately 5 months after initiation of her latest antimicrobial regimen of azithromycin, imipenem, and amikacin. Here, she was restarted on cefoxitin 2 g daily, amikacin 750 mg daily, and azithromycin 1000 mg daily. She completed an additional 4 months (a total of 9 months) of therapy with complete clinical resolution. In conclusion, clinical suspicion of M. abscessus infection is essential for the diagnosis. Patient compliance is integral to a successful outcome because the treatment involves prolonged duration, continuous intravenous antibiotics, and multiple potential adverse effects.
Respiratory Viruses in a Primary Health Care Facility in Amsterdam, the Netherlands
Authors: Bruning Andrea H.L. , de Kruijf Wilhelmina B. , van Weert Henk C.P.M. , Vrakking Anja , de Jong Menno D. , Wolthers Katja C. , Pajkrt Dasja 
Published: January 2018

Background
Laboratory testing for respiratory tract infections (RTIs) is not routinely performed in primary care. Their etiology is usually unknown, and although RTIs are mainly of viral origin, the contribution of different respiratory viruses is uncertain. Our study aims to increase our insight into the epidemiology of respiratory viruses in primary care and to evaluate the accuracy of the general practitioner's (GP's) clinical diagnosis of influenza virus infection.

Methods
We prospectively recruited patients who presented with RTI symptoms at a primary care facility in Amsterdam, the Netherlands, during the 2015–2016 winter season. Demographic and clinical characteristics of patients were summarized using a questionnaire. Nasopharyngeal swabs were collected and tested with a multiplex polymerase chain reaction assay detecting 14 respiratory viruses.

Results
One or more respiratory viruses were present in 42.5% of the patients (n = 353). The most frequently detected viruses were rhinovirus (11.6%), human coronavirus (8.8%), and influenza A virus (7.6%). Sensitivity of GP's clinical diagnosis for influenza virus infection was 52.6% and specificity was 78.3%.

Conclusions
Despite the use of a sensitive polymerase chain reaction, a respiratory virus could be detected in less than half of the patients visiting the GP with RTI symptoms. It is difficult to clinically distinguish influenza from other causes of RTIs. Correct etiological diagnosis of RTIs is needed because it contributes to differential diagnosis, might give direction to development of specific antiviral therapies and vaccines, reduce unnecessary prescription of antibiotics, and clarifies the clinical spectrum of the different respiratory viruses.
Epidemiologic Evaluation of Rothia Bacteremias
Authors: Shaeer Kristy M. , Addisu Anteneh , Nanjappa Sowmya , Greene John N. 
Published: January 2018

Background
Clinicians may have previously considered Rothia spp as a contaminant, nonpathogenic flora, or rare etiology of infection. These organisms have been acknowledged as opportunistic pathogens particularly in immunocompromised patients, yet a dearth of information exists regarding this species. Our study investigated the characteristics and clinical outcomes associated with Rothia bacteremias in cancer patients.

Methods
We performed a single-center retrospective cohort study of patients with cancer with a positive blood culture for Rothia spp, from December 1, 2012 to May 17, 2017 at the H. Lee Moffitt Cancer Center and Research Institute in Tampa, Fla.

Results
Thirty-six patients who predominantly had hematologic malignancies and profound and prolonged neutropenia were identified. All patients rapidly cleared the bacteremia as was demonstrated by subsequent negative blood cultures, which were rechecked 24 to 48 hours after initiation of intravenous antimicrobial therapy. Characteristics previously identified as predisposing factors in Rothia-associated infections were present in our patients such as fluoroquinolone prophylaxis (78%), receipt of chemotherapy (100%), mechanical ventilation (8%), and central venous catheters (100%). Complications arose where patients developed sepsis or systemic inflammatory response syndrome (n = 21), pneumonia (n = 3), cellulitis (n = 2), and meningitis (n = 1). Over 75% of with sensitivities were susceptible to penicillin. The average duration of therapy was 11 ± 6 days.

Conclusions

Rothia bacteremia is a rare infection and associated with rapid clearance upon initiation of appropriate antimicrobial therapy. In vitro susceptibility is now available and should be performed on all isolates to identify cases where antibiotic deescalation and resistance may occur.
An Optimal Partial Ossicular Prosthesis Should Connect Both to the Tympanic Membrane and Malleus: A Temporal Bone Study Using Laser Doppler Vibrometry
Authors: Niklasson Anders , Gladiné Kilian , Rönnblom Anton , von Unge Magnus , Dirckx Joris , Tano Krister 
Published: January 2018

Objective:
To compare stapes vibrations in different partial ossicular replacement prosthesis (PORP) applications.

Methods:
Stapedial vibrations were measured on fresh frozen human temporal bones with laser Doppler vibrometry. Eight different types of common ossiculoplasty methods were compared regarding recovery of stapes vibrations in relation with the normal ossicular chain. The PORPs were divided into three groups: 1) PORPs with the lateral contact only with the tympanic membrane, 2) PORPs with lateral contact only to the malleus handle, and 3) PORPs with lateral contact with both the malleus handle and the tympanic membrane.

Results:
The PORPs with lateral contact only to the malleus handle performed better than the PORPs with lateral contact to the tympanic membrane only at 2 kHZ, but the best recovery was found in the group with contact both to the malleus handle and the tympanic membrane.

Conclusion:
The best sound transmission might be achieved by placing a PORP in contact with both the tympanic membrane and the handle of the malleus.
The American Otological Society at its Sesquicentennial: Insights Into the Society's Formative Years
Authors: Jackler Robert K. , Alyono Jennifer C. , Mudry Albert C. 
Published: January 2018

Objective:
To elucidate the sequence of events which led to the formation of the American Otological Society (AOS) in 1868 and to examine the lives and contributions of the nine founding members of the Society.

Methods:
Study of primary historical documents, biographical material, and previous histories of the AOS.

Results:
Earlier treatments of the history of the AOS minimally covered the events and personalities from the Society's formative period. The founders of the AOS were much influenced by recent advances in European Otology and the success of the nascent American Ophthalmological Society which had been founded in 1864. The AOS has long credited Elkanah Williams as its first president of the AOS, although he never actually served in this role and was not a contributor to otological literature. Documents suggest that 30 years old New York physician Daniel Bennett St John Roosa, recently returned from a grand tour of the leading European otological centers, was the principal advocate for the creation of the AOS.

Conclusions:
The 1860s were a pivotal period in the maturation of American Otology. Previously, most “aurists” were widely considered to be charlatans who practiced unscientifically and often unscrupulously. The AOS founder generation were a group of Ophthalmologists who strove to elevate otology from being a lesser appendage of the mother field to becoming a respected and scientifically based medical specialty in its own right.