bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of medication adherence in chronic disease at a federally qualified health center
Authors: Oung Alvin B. , Kosirog Emily , Chavez Benjamin , Brunner Jason , Saseen Joseph J. 
Published: June 2017

Background: While medication adherence in chronic disease has been evaluated in the general population, limited data are available among Medicaid recipients, especially within federally qualified health centers (FQHCs). This study determined baseline medication adherence for Medicaid recipients receiving care in an FQHC for first-line medications used in hypertension, hyperlipidemia, and diabetes. Secondary outcomes included baseline adherence for individual patient factors. Methods: Patients from the Salud Family Health Centers, an FQHC with a large percentage of both Spanish-speaking patients and providers, were included in this study. Using retrospective prescription claims reports from 1 January 2015 to 1 October 2015, medication possession ratios (MPRs) and proportion of days covered (PDC) were calculated for each medication group. Patients with adherence ⩾0.80 were considered adherent. Results: From 1034 individual patients, 1788 medications were evaluated. Using MPRs, adherence rates were highest among medications for hypertension (67.2% adherent), followed by hyperlipidemia (67.0%), and lastly diabetes (58.0%); p < 0.001. Likewise, using PDC, adherence rates were highest for medications for hypertension (56.6%), followed by hyperlipidemia (52.2%), and lastly diabetes (45.0%); p = 0.010. Lower rates of adherence were seen among men, patients age 18–29 years old, African Americans, and patients with English documented as their preferred language. Conclusions: Although overall medication adherence rates within our FQHC patients were comparable with those in previous literature, differences seen among medication groups and patient individual factors suggest that there is still much to be learned in improving adherence. Future efforts will require a multifaceted approach, tailored to patient-specific needs.
Bach2 repression mediates Th17 cell induced inflammation and associates with clinical features of advanced disease in chronic pancreatitis
Authors: Sasikala M , Ravikanth VV , Murali Manohar K , Deshpande Neha , Singh Sandhya , Pavan Kumar P , Talukdar R , Ghosh Sudip , Aslam Mohsin , Rao GV , Pradeep R , Reddy D Nageshwar 
Published: June 2017

ObjectivesAltered immune homeostasis and involvement of T cells has been reported in chronic pancreatitis (CP). We evaluated the role of Bach2 (BTB and CNC homology basic leucine zipper transcription factor 2), a key regulator of immune homeostasis in the chronicity of CP.MethodsExpression of Bach2 and T‐cell transcription factors, enumeration of BACH2+/CD4+ T‐lymphocytes were performed by qRT‐PCR and flow cytometry respectively. Bach2 silenced human CD4+ T‐lymphocytes were exposed to CP tissue extract to assess T‐cell lineage commitment. Aryl hydrocarbon receptor (Ahr ) and Deubiquitinase enzyme A (DUBA/OTUD5gene ) were evaluated as markers of persistent Th17 cell differentiation. Bach2 gene (exons) was sequenced to identify risk variants and functionally validated.ResultsDecrease in Bach2 (p  < 0. 0001) and increase (p  < 0. 001) in TBX21, RORC, Ahr, PRDM1, IL23R mRNA were noted in pancreatic tissues, while BACH2+/CD4+ T‐lymphocytes were decreased (p  < 0.01) in circulation and tissues. Exposure of Bach2 silenced CD4+ T‐lymphocytes to CP tissue extract showed increased Ahr, decreased OTUD5, and enhanced Th17 cell differentiation. Sequencing of Bach2 gene revealed association of novel variant (rs9111 in 5′‐UTR) with advanced disease and luciferase assay confirmed its role in Bach2 repression.ConclusionBach2 repression mediates Th17 cell induced inflammation and rs9111‐TT in individuals with primary genetic susceptibility to CP is associated with clinical features of advanced disease.
Transarterial chemoembolization versus sorafenib in patients with hepatocellular carcinoma and extrahepatic disease
Authors: Kirstein Martha M , Voigtländer Torsten , Schweitzer Nora , Hinrichs Jan B , Marquardt Jens , Wörns Marcus‐Alexander , Kloeckner Roman , Fründt Thorben W , Ittrich Harald , Wacker Frank , Rodt Thomas , Manns Michael P , Wege Henning , Weinmann Arndt , Vogel Arndt 
Published: June 2017

BackgroundSorafenib is the recommended treatment for advanced hepatocellular carcinoma (HCC), but transarterial chemoembolization (TACE) is performed in individual cases with limited extrahepatic spread. The aim of this study was to compare the outcome of patients with HCC and extrahepatic disease (EHD) treated with sorafenib and TACE.MethodsA total of 172 patients with HCC and EHD treated with sorafenib (n  = 98) or TACE (n  = 74) at three German referral centers (Hannover, Mainz and Hamburg) were included in this study. In order to reduce selection bias, patients were matched for significant demographic differences using a propensity score analysis.ResultsPatients with liver cirrhosis, higher extrahepatic tumor burden and/or infiltration of adjacent organs/structures were significantly more often treated with sorafenib. Median overall survival (OS) was similar for sorafenib‐ and TACE‐treated patients (7 versus 8 months, p  = 0.312). In a propensity score analysis matched for demographic differences, median OS remained similar with 4 versus 8 months for sorafenib versus TACE (p  = 0.613).ConclusionTreatment with TACE is not inferior to treatment with sorafenib in patients with limited EHD of HCC. TACE represents an effective therapeutic option in selected patients with EHD.
Arthroscopic fixation of acute acromioclavicular joint disruption with TightRope™: Outcome and complications after minimum 2 (2–5) years follow-up
Authors: Zhang Li-Feng , Yin Bo , Hou Su , Han Bing , Huang De-fa 
Published: June 2017

Purpose: To evaluate the midterm results of arthroscopic reconstruction of acute acromioclavicular (AC) joint disruption using TightRope™ system. Methods and Material: We retrospectively assess the results of 24 patients of acute AC joint dislocation who were operated using TightRope system. Constant and University of California, Los Angeles (UCLA) scores and coracoclavicular distance were calculated pre- and postoperatively. Data was entered into MS excel and analyzed using the SPSS version 17. Results: The mean follow-up was 39.45 months. Constant and UCLA scores were significantly increased postoperatively. Six patients had partial loss of reduction within 3–6 months and two patients had a failure of construct. Constant score was significantly lower in these patients. Conclusion: TightRope reconstruction of the AC joint is a reproducible and safe alternative to many other techniques of AC joint reconstruction. Early subluxation remains a concern and may reflect the need for technique modification.
The body, the garment and the Kantian sublime in fashion
Authors: Barnard Malcolm 
Published: June 2017

Abstract
This article concerns the ways in which Kant’s account of the sublime may be used to explain fashion. It uses examples from designer Rei Kawakubo and theorist Elizabeth Wilson to introduce the argument that our everyday experiences of the body, the garment and fashion are actually experiences of the sublime. In order to make this argument, the article places these experiences in a western philosophical tradition by considering Hegel’s early-nineteenth-century account of the relation between the garment and the body. The article then argues that Roland Barthes’s account of Erté’s alphabet-drawings is a critique of Hegel and Wilson, and that it presupposes Kant’s idea of the sublime. The article provides an account of Kant’s sublime in the Critique of Judgement, written in 1790, relating it back to his account of the schematism in the Critique of Pure Reason (written in 1781). The conclusion is that the experience of the sublime, of the inadequacy that is necessarily involved in the application of concepts to intuitions or in the subsumption of intuitions under concepts, is found in all experience and thus that fashion is always constituted by the experience of the sublime.
The impact of participation in creative drama on empathy levels in emerging adulthood: A pilot study
Authors: Scroggs Barrett , Bailey Sally , Fees Bronwyn 
Published: June 2017

Abstract
The current study explored the impact of participation in a creative drama course on emerging adults’ levels of empathy. Students enrolled in a creative drama class participated in this pilot study utilizing a prepost-test design. Mean comparisons revealed a significant difference in perspective taking post course. Results suggest that this group experienced a cognitive shift over time in their ability to think about the perspective of another.
Attachment, distancing, and the working alliance in drama therapy
Authors: Henson Alisha M. , Fitzpatrick Marilyn 
Published: June 2017

Abstract
This study investigates the interaction of attachment styles and drama therapy (DT) techniques at various levels of therapeutic distance during brief therapy. Five mothers with children diagnosed with psychiatric disorders participated in a DT support group. Mother attachment styles and their responses to DT techniques were assessed using the Relationships Scales Questionnaire (RSQ). Participants had insecure attachment styles and appeared to prefer an overdistanced approach. Therefore, attuning to client attachment styles may help drama therapists titrate distance and support the therapeutic process.
Towards a drama therapy pedagogy: An a/r/tographic study using dramatic improvisation
Authors: Bird Drew , Tozer Katy 
Published: June 2017

Abstract
This article explores the role of the art form in both research and teaching practice for the delivery of an MA drama therapy program in the United Kingdom. A/r/tography as the chosen research methodology makes central the artistic process to inform teaching and research through ongoing reflexivity using dramatic improvisation. Seven phases (renderings) illustrate the development towards formulating a drama therapy pedagogy. The authors explore disseminating the research through performance as another form of praxis.
Surface condition, microstructure and microhardness of boronized layers produced on Vanadis-6 steel after modification by diode laser
Authors: Bartkowska Aneta , Jurči Peter , Bartkowski Dariusz , Przestacki Damian , Hudáková Mária 
Published: June 2017

Abstract
The paper presents the study results of surface condition, microstructure and microhardness of Vanadis-6 tool steel after diffusion boriding and laser modification by diode laser. As a result of diffusion boriding the layers consisted of two phases: FeB and Fe2B. A bright area under the continuous boronized layers was visible. This zone was probably rich in boron. As a result of laser surface modification of boronized layers, the microstructure composed of three zones: remelted zone, heat affected zone and the substrate was obtained. The microstructure of remelted zone consisted of boron-martensite eutectic. The depth of laser track (total thickness of remelted zone and heat affected zone) was dependent on laser parameters (laser beam power density and scanning laser beam velocity). The microhardness of laser remelting boronized layer in comparison with diffusion boronized layer was slightly lower. The presence of heat affected zone was advantageous, because it allowed to obtain a mild microhardness gradient between the layer and the substrate.
Study of the refractive index of gasoline+alcohol pseudo-binary mixtures
Authors: Nita Irina , Geacai Elis , Iulian Olga , Osman Sibel 
Published: June 2017

Abstract
The properties of gasoline change as a result of blending with a bioalcohol, affecting the behavior of the pseudo-binary system. The aim of this paper is to present experimental data of the refractive index for pseudobinary mixtures of a reformate gasoline with ethanol, isopropanol and n-butanol over the entire composition range and for temperature ranging from 293.15 K to 313.15 K. The accuracy of different equations to predict the refractive index of the mixtures was tested. The best prediction accuracy (the lower AAD) corresponded to Eykman and Lorentz-Lorenz mixing rules. A logarithmic equation proposed to correlate the refractive index with composition and temperature of gasoline+alcohol mixtures showed a good accuracy (the absolute average deviation AAD < 0.052%). The deviations in refractive index for investigated systems are negative over the entire composition range and at all investigated temperatures.
DFT study of anthocyanidin and anthocyanin pigments for Dye-Sensitized Solar Cells: Electron injecting from the excited states and adsorption onto TiO2 (anatase) surface
Authors: Marcano Emildo 
Published: June 2017

AbstractWe explored, the absorption spectra, excited states and electronic injection parameters of anthocyanidin and anthocyanin pigments using the level of theory (TD)CAM-B3LYP/6-31+G(d,p). For the most isolated dyes, the distribution pattern of HOMO and LUMO spreads over the whole molecules, which lead an efficient electronic delocalization. The calculated light harvesting efficiencies (LHEs) are all near unity. Methoxy group in peonidin molecule lead the largest oscillator strength and LHE. The presence of water lead a higher spontaneous electronic inject process, with ΔG
The Claim of Right to Property: Social Violence and Political Right
Authors: Douglass Patrice D. 
Published: June 2017

Abstract
This article offers a close reading of The Order of Things by Michael Foucault and The Human Condition by Hannah Arendt, to argue that the positioning of the Human within scientific and political thought necessitates an underscoring of violence as it relates to blackness. This position interrogates how Arendt positions slavery in the Greek polis and the Roman res republica to establish her foci on modern political life. I offer an analysis of Prigg v. The Commonwealth of Pennsylvania, as complicating Arendt’s political dichotomy, by shifting focus to the legal history of US American slavery. Prigg rewrites and establishes the demarcations of US Federal and State law. However, the majority opinion and dissents make fleeting reference to the fugitive slave in question, Margaret Morgan, and the possibility that she may have been sexually violated while being forcibly returned to slavery. I conclude that the contours of this case, specifically the erasure of sexual violence, demonstrate how racial slavery provides contexts to modern political life not explored by Arendt’s primary concern with slavery in antiquity.
The Visual Life of Black Queer Diaspora
Authors: Smalls James 
Published: June 2017

Abstract
In this essay, I consider the ways in which the visual representations of four contemporary black queer diaspora artists – Nicholas Hlobo (South Africa), Zanele Muholi (South Africa), James Chuchu (Kenya), and Adejoke Tugbiyele (American-born Nigerian) – constitute, reflect, and challenge the porous intersectionality associated with the concepts ‘black,’ ‘queer,’ and ‘diaspora.’ The essay foregrounds the inter- and trans-cultural processes of visuality in highlighting the shifting terrains of black (African) and queer diasporic concerns that reside and circulate in physical and ideological spaces beyond the Anglo- and US-centric ones. As well, what follows offers the potential for opening up new horizons and nuanced significations within and beyond these categories. The investigation begins broadly by first exploring the slipperiness of the notions ‘black,’ ‘queer,’ and ‘diaspora,’ and then examines selected forms of visual representation that both sustain and disrupt the intersecting dimensions of these ideas. The essay takes interest in envisioning a diasporic future that liberates black queer lives and imagination.
Phase Characteristics of the Countermovement Jump Force-Time Curve: A Comparison of Athletes by Jumping Ability
Authors: Sole Christopher J. , Mizuguchi Satoshi , Sato Kimitake , Moir Gavin L. , Stone Michael H. 
Published: June 2017

Abstract
Sole, CJ, Mizuguchi, S, Sato, K, Moir, GL, and Stone, MH. Phase characteristics of the countermovement jump force-time curve: a comparison of athletes by jumping ability. J Strength Cond Res 32(4): 1155–1165, 2018—The purpose of this study was to compare the phase characteristics of the countermovement jump (CMJ) force-time (F-t) curve between athletes based on jumping ability. An initial sample of one-hundred fifty Division-I collegiate athletes were ranked based on CMJ height. Three performance groups were then formed by taking the top, middle, and lower 30 athletes (15 men and 15 women) from the sample. Phases of the CMJ F-t curve were determined and then characterized by their duration, magnitude, area (impulse), and shape (shape factor). A series of 3-way mixed analysis of variance were used to determine statistical differences in phase characteristics between performance groups as well as between male and female athletes. Statistically significant phase-by-performance group interactions were observed for relative phase magnitude (p < 0.001), relative phase impulse (p < 0.001), and shape factor (p = 0.002). Phase-by-sex interactions were statistically significant for both relative phase magnitude (p < 0.001) and relative phase impulse (p < 0.001). Post hoc comparisons indicated that higher jumpers exhibited larger relative magnitude and impulse in the phases contained within the positive area of the F-t curve. Similarly, relative phase magnitude and impulse were the only phase characteristics to be statically different between men and women. Finally, the relative shape of the phase representing the initial rise in force was found to relate to jump height. These results provide some information regarding the diagnostic value of qualitative analysis of the CMJ F-t curve.
In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism
Authors: Salvatori Roberto , Radian Serban , Diekmann Yoan , Iacovazzo Donato , David Alessia , Gabrovska Plamena , Grassi Giorgia , Bussell Anna-Marie , Stals Karen , Weber Astrid , Quinton Richard , Crowne Elizabeth C , Corazzini Valentina , Metherell Lou , Kearney Tara , Du Plessis Daniel , Sinha Ajay Kumar , Baborie Atik , Lecoq Anne-Lise , Chanson Philippe , Ansorge Olaf , Ellard Sian , Trainer Peter J , Balding David , Thomas Mark G , Korbonits Márta 
Published: June 2017

ObjectiveMutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are associated with pituitary adenoma, acromegaly and gigantism. Identical alleles in unrelated pedigrees could be inherited from a common ancestor or result from recurrent mutation events.Design and methodsObservational, inferential and experimental study, including:AIPmutation testing; reconstruction of 14AIP-region (8.3 Mbp) haplotypes; coalescent-based approximate Bayesian estimation of the time to most recent common ancestor (tMRCA) of the derived allele; forward population simulations to estimate current number of allele carriers; proposal of mutation mechanism; protein structure predictions; co-immunoprecipitation and cycloheximide chase experiments.ResultsNine European-origin, unrelated c.805_825dup-positive pedigrees (four familial, five sporadic from the UK, USA and France) included 16 affected (nine gigantism/four acromegaly/two non-functioning pituitary adenoma patients and one prospectively diagnosed acromegaly patient) and nine unaffected carriers. All pedigrees shared a 2.79 Mbp haploblock aroundAIPwith additional haploblocks privately shared between subsets of the pedigrees, indicating the existence of an evolutionarily recent common ancestor, the ‘English founder’, with an estimated median tMRCA of 47 generations (corresponding to 1175 years) with a confidence interval (9–113 generations, equivalent to 225–2825 years). The mutation occurred in a small tandem repeat region predisposed to slipped strand mispairing. The resulting seven amino-acid duplication disrupts interaction with HSP90 and leads to a marked reduction in protein stability.ConclusionsThe c.805_825dup allele, originating from a common ancestor, associates with a severe clinical phenotype and a high frequency of gigantism. The mutation is likely to be the result of slipped strand mispairing and affects protein–protein interactions and AIP protein stability.
Efeito da língua, estilo de elocução e sexo do falante sobre medidas globais da frequência fundamental
Authors: Arantes Pablo , Linhares Maria Érica Do Nascimento 
Published: June 2017

Analisamos o efeito do sexo, do estilo de elocução e da língua (alemão, estoniano, francês, inglês, italiano, português e sueco) sobre estimadores de tendência central e dispersão da frequência fundamental da fala. Os estilos são entrevista, leitura de frases e de palavras. As línguas diferem entre si em termos do valor típico de F0 usado por seus falantes. O estilo leitura de frases apresenta valores maiores do que a entrevista, mas o efeito não é uniforme entre as línguas. Diferenças significativas entre o estilo leitura de palavras e entrevista são mais raros. Todos os estimadores de tendência central estudados sofreram efeitos dos três fatores testados. Os homens apresentaram variabilidade de F0 ligeiramente maior do que as mulheres de forma significativa em três de cinco estimadores. O estilo entrevista tem maior variabilidade em dois. As línguas não diferem em termos de variabilidade de F0.********************************************************************Effect of language, speaking style and speaker sex on global measures of fundamental frequencyWe analyze the effect of speaker sex, speaking style and language (English, Estonian, French, German, Italian, Portuguese, Swedish) on global statistical measures of the voice fundamental frequency. The styles studied are interview, sentence reading and word list reading. Typical F0 values used by speakers among languages differ both in male and female speakers. Sentence reading has slightly higher values than interview, but the effect is not uniform among languages. In few cases word reading and interview values differ significantly. All central tendency estimators are affected by the variables tested. Three out of five estimators of dispersion show slightly higher values for male than for female speakers. Among styles, the interview has higher standard deviation and coefficient of variation. Languages do not differ among themselves in terms of F0 variability.Keywords: Fundamental frequency; Acoustic phonetics; Speaking styles; Sociophonetics
ЕКОНОМІКА ВРАЖЕНЬ – СУЧАСНИЙ ЕТАП РОЗВИТКУ СУСПІЛЬНОГО ВИРОБНИЦТВА
Authors: Дишкантюк О. В. 
Published: June 2017

В статті розглянуто передумови розвитку економіки вражень як сучасного етапу суспільного виробництва; визначено сутність кінцевих та проміжних послуг сфери гостинності та кінцевого її продукту; досліджено логістичні ланцюги сфери гостинності, що формують продукт гостинності та наведено приклади їх існування.