bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of pedotransfer functions for the determination of saturated hydraulic conductivity coefficient
Authors: Ryczek Marek , Kruk Edyta , Malec Magdalena , Klatka Sławomir 
Published: March 2017

Abstract
On one hand, direct methods of measurement of saturated hydraulic conductivity coefficient are time consuming, and on the other hand, laboratory methods are cost consuming. That is why the popularity of empirical methods has increased. Their main advantages are speed of calculations and low costs. Comparison of various empirical methods (pedotransfer functions) for the determination of saturated hydraulic conductivity coefficient was the purpose of this work. The methods used were Shepard’s, Hazen’s, USBR (United States Bureau of Reclamation), Saxton et al.’s, Kozeny–Carman’s, Krüger’s, Terzaghi’s, Chapuis’s, Sheelheim’s, Chapuis’, and NAVFAC (Naval Facilities Engineering Command) methods. Calculations were carried out for the soil samples of differential texture. The obtained results shows the methods used for the determination of permeability coefficient differ considerably. Mean values obtained by analysed methods fluctuated between 0.0006 and 12.0 m·day−1. The results of calculations by the chosen methods were compared with the results of the laboratory method. The best compatibility with laboratory method was obtained by using the Terzaghi method.
Application of Local Hyperbaric Oxygen Therapy With Use of Device Laserobaria – S in the Treatment of Chronic Wounds
Authors: Sieroń Aleksander , Pasek Jarosław , Pietrzak Mikołaj , Cieślar Grzegorz 
Published: March 2017

Abstract
For many years now we have been observing a growing number of patients with amputations performed on lower extremities due to chronic wounds occurring as a result of atherosclerotic lesions in peripheral arteries, thromboembolism as well as due to chronic ischaemia in lower extremities. Modern physical medicine is systematically enhancing treatment possibilities for patients with chronic wounds by an introduction of innovative therapeutic devices into clinical practice, which often allow to prevent amputations, accelerate the healing process, and, most of all, alleviate or completely eliminate pain. The article presents the therapeutic mechanism and methodology of one of such methods - local hyperbaric oxygen therapy with the use of a device called LASEROBARIA - S, alongside a description of its therapeutic effects in the case of two patients.
A Case of Cutaneous Leishmaniasis Treated with Hyperbaric Oxygen Therapy
Authors: Olszański Romuald , Siermontowski Piotr , Juszczak Dariusz , Dąbrowiecki Zbigniew , Pedrycz Agnieszka 
Published: March 2017

Abstract
Cutaneous leishmaniasis in Poland is an imported disease mainly occurring in tourists who travelled to tropical countries. Cutaneous symptoms occur as late as between ten and twenty days following the return from the tropics. Lesions connected with cutaneous leishmaniasis were most commonly diagnosed by Polish doctors as furuncle, ecthyma or ulceration and ineffectively treated for several weeks with antibiotics.
The paper presents the case of leishmaniasis in a 30-year-old male with an ulceration of the left shank, ineffectively treated with antibiotics over a period of four months. The ulceration was healed completely only after leishmaniasis was diagnosed and following the application of a treatment based on antimony derivatives, followed by hyperbaric oxygenation performed in a hyperbaric chamber.
Physical Activity in the Water Accompanied by Music
Authors: Kwaśna Anna , Szczepan Stefan , Spirydowicz Aleksandra , Zatoń Krystyna 
Published: March 2017

Abstract
Introduction: Music motivates, relaxes and stimulates action and is one factor which enhances the pleasure that people feel from a given movement. Thus, from a psychophysical point of view, listening to music is an important aspect in sport and recreation. With this in mind, the aim of the study was to determine any changes in the participants’ psychophysical sphere which resulted from listening to music while swimming. The psychophysical sphere was expressed in relation to the Borg RPE scale (Rating of Perceived Exertion) as well as the Rejeski and Gauvin Exercise-Induced Feeling Inventory (EFI) scale of emotional states.
Material and methods: The participants in the study were not professional swimmers (n = 10). The experiment consisted of two trials in which participants performed the Swimming Cooper test. During the first trial there was no music transmitted while in the second trial specifically selected music was played as the participants swam.
Results: An ANOVA variance analysis (α = 0.05) showed statistically significant differences in the RPE scale (p = 0.04) and across all sensations on the EFI scale (p = 0.001, p = 0.001, p = 0.001, p = 0.001).
Conclusions: Listening to music while swimming has a significant impact on the human psychophysical sphere and is expressed by a perceived exertion scale and the scale of emotional states.
Respondents paid less attention to the discomfort of physical exertion associated with exercise while listening to music. The rating of their emotional states, including positive engagement, revitalization and tranquility considerably increased though the physical exhaustion measures were significantly lower.
Gesundheitskompetenz messen – Kritischer Blick auf standardisierte Verfahren
Authors: Bitzer Eva Maria 
Published: March 2017

Zusammenfassung
Die mehr als 120 standardisierten Verfahren zur Erhebung der Gesundheitskompetenz unterscheiden sich u.a. danach, ob sie als Testinstrumente oder zur Selbsteinschätzung konzipiert sind. Selbsteinschätzungsfragebögen erfreuen sich hoher Akzeptanz, sind in der Regel mehrdimensional, jedoch mitunter konzeptionell unscharf. Dagegen liefern Testinstrumente objektivierbare Informationen, konzentrieren sich jedoch oft eng auf das Textverständnis und Wissen und sind weit weniger bei den Befragten akzeptiert.
Gesundheitskompetente Krankenbehandlungseinrichtungen
Authors: Pelikan Jürgen M. 
Published: March 2017

Zusammenfassung
Gesundheitskompetenz (GK) wird zunehmend als umfassendes und relationales Konzept verstanden, d.h. sowohl persönliche wie organisationale GK kann gemessen und verbessert werden. Aufbauend auf 10 Merkmalen der Gesundheitskompetenten Krankenbehandlungsorganisation des Institute of Medicine (IOM) hat ein Wiener Team ein umfassendes Modell mit Standards und Indikatoren zur Selbstbewertung der organisationalen Gesundheitskompetenz von Krankenbehandlungseinrichtungen entwickelt und in einer Machbarkeitsstudie validiert.
Abwehrreaktionen und negative Effekte von Gesundheitsinformationen
Authors: Hastall Matthias R. 
Published: March 2017

ZusammenfassungGesundheitsbezogene Informationen können eine Reihe negativer Effekte und Abwehrreaktionen auslösen, die bislang kaum thematisiert oder bei der Informationsgestaltung berücksichtigt werden. Der Beitrag gibt Hinweise auf einige zentrale Barrieren für die erfolgreiche Erhöhung der Gesundheitskompetenz und plädiert für eine intensivierte Diskussion über kommunikationsleitende Menschenbilder sowie unbewusste Prozesse der Informationszuwendung und -verarbeitung.
Gesundheitskompetenz im Alter fördern – Partizipative Interventionsentwicklung im Projekt „GeWinn“
Authors: Killenberg Alvia , Ladebeck Nadine , Baumgarten Kerstin , Hassel Holger 
Published: March 2017

Zusammenfassung
Die Häufigkeit chronischer Erkrankungen nimmt mit dem Alter zu. Zugleich haben besonders ältere Menschen eine unzureichende Gesundheitskompetenz. Das Projekt „GeWinn“ zielt auf die Förderung der Gesundheitskompetenz von Menschen ab 60 Jahren in den Bereichen der Gesundheitsförderung und im Umgang mit chronischen Erkrankungen. In diesem Beitrag soll die partizipative Entwicklung der „GeWinn“-Intervention anhand der Durchführung und Auswertung von sieben Fokusgruppendiskussionen aufgezeigt werden.
Faktenboxen – Wie passen Evidenz und Laienverständlichkeit zusammen?
Authors: Kolpatzik Kai 
Published: March 2017

Zusammenfassung
Qualitätsgesicherte Gesundheitsinformationen sind für Laien oft schwer zu finden und zu verstehen. Faktenboxen bereiten Gesundheitsinformationen aus wissenschaftlichen Studien in einem prägnanten Frage-Antwort-Prinzip auf und stellen zentrale Informationen in einer tabellarischen oder grafisch unterstützten Form zusammen. Es wird keine Empfehlung gegeben. Die Wissensvermittlung soll Menschen befähigen, eine informierte Entscheidung treffen zu können.
Gesundheitskompetenz in Deutschland – Nationaler Aktionsplan
Authors: Schaeffer Doris , Berens Eva-Maria , Weishaar Heide , Vogt Dominique 
Published: March 2017

Zusammenfassung
Die erste repräsentative Studie zur Gesundheitskompetenz in Deutschland (HLS-GER) zeigt, dass über die Hälfte der Bevölkerung über eine eingeschränkte Gesundheitskompetenz verfügt. Deshalb wird ein Nationaler Aktionsplan erarbeitet, dessen Ziel es ist, ein systematisches Programm zur Förderung der Gesundheitskompetenz zu entwickeln, die gesellschaftliche und politische Diskussion des Themas zu intensivieren, Handlungsbereitschaft auf unterschiedlichen Ebenen zu erzeugen und Veränderungen anzuregen.
Patentrezept Medienkompetenz. Ein Weg zur Steigerung der Gesundheitskompetenz?
Authors: Braun Bernard 
Published: March 2017

Zusammenfassung
Die Bevölkerungsgruppe mit mangelhafter Gesundheitskompetenz ist wegen der rund 15% Analphabeten wahrscheinlich noch erheblich größer als berichtet. Wegen der Mängel der medialen Gesundheitsinformationen und bei der Hilfe von Ärzten ihren Patienten evidente Informationen zu beschaffen, ist das Ziel von besserer Gesundheitskompetenz allein durch mehr Medienkompetenz oder Arztgespräche nicht zu erreichen. Dies ist nur durch gleichzeitige Eingriffe auf der Angebotsseite zu schaffen.
Properties and applications of electrically conductive
thermoplastics for additive manufacturing of sensors
Authors: Hampel Benedikt , Monshausen Samuel , Schilling Meinhard 
Published: March 2017

Abstract
In consequence of the growing
diversity of materials in the fused deposition modeling 3D printing
technique, electrically conductive materials are
commercially available. In this work two filaments based
on thermoplastics filled with carbon or metal nanoparticles are analyzed in
terms of their electrical conductance. The printing
parameters to process the materials with the 3D printer are optimized with
the design of experiments (DoE) method. A model to
calculate the resistance of such 3D printed structures is presented and
a demonstrator as a proof of concept was 3D printed based on these
results. In addition, 3D printing of
capacitors is investigated.
Fragile X syndrome: Lessons learned from the most translated neurodevelopmental disorder in clinical trials
Authors: Duy Phan Q. , Budimirovic Dejan B. 
Published: March 2017

AbstractFragile X syndrome (FXS) is the leading genetic cause of autism spectrum disorder (ASD) and inherited intellectual disability (ID) worldwide. Preclinical successes in understanding the biology of FXS have led to numerous translational attempts in human clinical trials of therapeutics that target the excitatory/inhibitory neural signaling imbalances thought to underlie FXS. Despite the preclinical success story, the negative results of the human clinical trials have been deemed to be at least in part disappointing by the field. In this commentary, we contend that such negative studies results in clinical trials may actually propel the FXS field forward by serving as important lessons for designing and implementing improved future clinical trials such that can objectively assess the full range of responses to new therapeutics.
Friedrich Theodor Vischer’s Shakespeare Criticism
Authors: Hahn Hans-Joachim 
Published: March 2017

Abstract
Vischer’s Shakespeare studies not only provide valuable insights into the bard’s plays, they also advance the type of positivist approach later practised by Bradley and others. This study focuses on Hamlet, the play most prominent in nineteenth-century German Shakespeare criticism. Two aspects are of particular interest: (1) Vischer’s nationalist approach, placing Shakespeare solely into a Northern European, Germanic environment. (2) Vischer’s primary concern with character studies. By removing Hamlet from the idealised pedestal on which the Romantics had placed him, Hamlet is no longer seen as the philosopher prince, tormented by moral scruples, but as caught in a net of adverse circumstances which he has to overcome in order to fulfil his father’s command. Vischer thereby liberates Shakespeare criticism from the constraints of domestic tragedy and its bourgeois morality.
Paranoid Masculinity in a Woman’s Mansion: Henry James’ “The Aspern Papers”
Authors: Bauer Gero 
Published: March 2017

AbstractOver the last decades, literary scholarship has increasingly recognised the importance of Henry James’ fiction for an understanding of late-nineteenth- and early-twentieth-century dynamics of genders and sexualities. In his writing, James repeatedly demonstrates how modern patriarchal masculinities fail to establish themselves as stable identities. On a textual level, he employs a ‘queer rhetoric’ that allows for readings beyond the normative axes masculine-feminine/homosexual-heterosexual. In this paper, I discuss how James, in his tale “The Aspern Papers” (1888), turns traditionally gendered power relations upside-down: while the patriarchal home is the domestic centre of the narrative, it is two women who are in control of its secrets. The male protagonist, a nameless editor, has to rely on the women’s willingness to let him in on their secret, allow him access to the letters of the dead poet Jeffrey Aspern, which he assumes to be in their possession, and, hence, let him face his own unspeakable secret in a ‘closet’ that is not his own.
Scalp hair cortisol for diagnosis of Cushing’s syndrome
Authors: Wester Vincent L , Reincke Martin , Koper Jan W , van den Akker Erica L T , Manenschijn Laura , Berr Christina M , Fazel Julia , de Rijke Yolanda B , Feelders Richard A , van Rossum Elisabeth F C 
Published: March 2017

Objective
Current first-line screening tests for Cushing’s syndrome (CS) only measure time-point or short-term cortisol. Hair cortisol content (HCC) offers a non-invasive way to measure long-term cortisol exposure over several months of time. We aimed to evaluate HCC as a screening tool for CS.

Design
Case-control study in two academic referral centers for CS.

Methods
Between 2009 and 2016, we collected scalp hair from patients suspected of CS and healthy controls. HCC was measured using ELISA. HCC was available in 43 confirmed CS patients, 35 patients in whom the diagnosis CS was rejected during diagnostic work-up and follow-up (patient controls), and 174 healthy controls. Additionally, we created HCC timelines in two patients with ectopic CS.

Results
CS patients had higher HCC than patient controls and healthy controls (geometric mean 106.9 vs 12.7 and 8.4 pg/mg respectively, P < 0.001). At a cut-off of 31.1 pg/mg, HCC could differentiate between CS patients and healthy controls with a sensitivity of 93% and a specificity of 90%. With patient controls as a reference, specificity remained the same (91%). Within CS patients, HCC correlated significantly with urinary free cortisol (r = 0.691, P < 0.001). In two ectopic CS patients, HCC timelines indicated that cortisol was increased 3 and 6 months before CS became clinically apparent.

Conclusions
Analysis of cortisol in a single scalp hair sample offers diagnostic accuracy for CS similar to currently used first-line tests, and can be used to investigate cortisol exposure in CS patients months to years back in time, enabling the estimation of disease onset.
Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study
Authors: Shanbhogue Vikram V , Støving René Klinkby , Frederiksen Katrine Hartmund , Hanson Stine , Brixen Kim , Gram Jeppe , Jørgensen Niklas Rye , Hansen Stinus 
Published: March 2017

Objective, design and methods
Roux-en-Y gastric bypass (RYGB) has proved successful in attaining sustained weight loss but may lead to metabolic bone disease. To assess impact on bone mass and structure, we measured a real bone mineral density at the hip and spine by dual-energy X-ray absorptiometry, and volumetric BMD (vBMD) and bone microarchitecture at the distal radius and tibia by high-resolution peripheral quantitative CT in 25 morbidly obese subjects (15 females, 10 males) at 0, 12 and 24 months after RYGB. Bone turnover markers (BTMs), calciotropic and gut hormones and adipokines were measured at the same time points.

Results
After a 24.1% mean weight loss from baseline to month 12 (P < 0.001), body weight plateaued from month 12 to 24 (−0.9%, P = 0.50). However, cortical and trabecular vBMD and microarchitecture deteriorated through the 24 months, such that there was a 5 and 7% reduction in estimated bone strength at the radius and tibia respectively (both P < 0.001). The declines observed in the first 12 months were matched or exceeded by declines in the 12- to 24-month period. While a significant increase in BTMs and decrease in leptin and insulin were seen at 24 months, these changes were maximal at month 12 and stabilized from month 12 to 24.

Conclusions
Despite weight stabilization and maintenance of metabolic parameters, bone loss and deterioration in bone strength continued and were substantial in the second year. The clinical importance of these changes in terms of increased risk of developing osteoporosis and fragility fractures remain an important concern.
Congenital toxoplasmosis: perception of knowledge and primary prevention measures among healthcare professionals and pregnant women treated in public healthcare facilities
Authors: De Moura Fernanda Loureiro , Millar Patricia Riddell , Fonseca Ana Beatriz Monteiro , Amendoeira Maria Regina Reis 
Published: March 2017

Aims: To evaluate knowledge about toxoplasmosis among pregnant women and healthcare professionals and to evaluate the knowledge acquired by pregnant women after health education actions. Methods: Five hundred pregnant women and 141 healthcare professionals from health units in Niterói, state of Rio de Janeiro, answered a questionnaire, received information about toxoplasmosis and had access to an interactive educational model and to folders between 2013 and 2016. After 3 months, 145 pregnant women answered the questionnaire once again. Results: Of 500 pregnant women, 226 (45.2%) reported having heard about toxoplasmosis. Among these, 23.5% had obtained information from friends and 19.0% from their doctors. About their exposure to risk factors, 6.8% had had contact with cat feces; 14.0% had had contact with soil without gloves; 23.4% had ingested undercooked meat; and 24.0% had drunk unfiltered water from the public supply system. The questionnaires of 145 pregnant women before and after the educational activities were compared and showed that contact with soil without gloves dropped significantly from 11.0% to 4.8% (p = 0.022) while consumption of unfiltered water fell from 26.9% to 20.0% (p < 0.001). Washing foods (62.1%), washing hands (62.1%) and consumption of well-cooked meat (61.4%) were the most widely cited preventive measures. Many mistakes were reported among healthcare professionals, and one nursing technician and 13 community healthcare agents (9.9%) had not heard about toxoplasmosis. Conclusions: Lack of knowledge about toxoplasmosis by most of the interviewed pregnant women, in addition to the misconceptions observed among healthcare professionals, leads to the conclusion that little importance has been given so far to primary prevention of toxoplasmosis during the prenatal period. Also, health professionals’ inadequate knowledge could be detrimental to secondary prevention, which consists of early detection and treatment of toxoplasmosis during pregnancy. In this study, educational intervention contributed to improving knowledge about the transmission and prevention of toxoplasmosis by pregnant women and, to a lesser extent, to reducing exposure to some risk factors.
Evaluation of postoperative pain relief with intra-peritoneal bupivacaine instillation in laparoscopic cholecystectomy- a randomized control study
Authors: Agrawal Saurabh , Pai Srinivas 
Published: March 2017

Background: Laparoscopic cholecystectomy is the surgical procedure of choice for symptomatic cholelithiasis due to the improved postoperative course, but patients undergoing laparoscopic cholecystectomy during the first 24 hours postoperatively complaints of pain. This study was designed to study the efficacy of intraperitoneal bupivacaine in reducing the initial postoperative pain and also to evaluate the postoperative shoulder tip pain, nausea and vomiting.Methods: Patients undergoing laparoscopic cholecystectomy were randomized into two groups the, study group received intraperitoneal bupivacaine 100mg at the end of the procedure and the control group received intraperitoneal saline. Post operatively patients were assessed for pulse rate, blood pressure, VAS, VRS, shoulder pain and nausea and vomiting at 0, 2, 6 and 24 hours.Results: Among the 50 patients studied, our study proved that there is no statistical significant reduction in pain with intraperitoneal bupivacaine. The VAS at 0, 2, 6 and 24 hours calculated with non-significant p-value of 0.85,0.29, 0.72 and 0.64 respectively and the VRS had p-value of 0.16, 0.08, 0.59 and 0.46 respectively and the doses of rescue analgesia consumed had p value of 0 .67, 0.61 and 0.70 which were not significant statistically.Conclusions: Instillation of 100mg bupivacaine did not significantly reduce the need for tramadol compared with saline.
Enhanced Oral Bioavailability of Domperidone with Piperine in Male Wistar Rats: Involvement of CYP3A1 and P-gp Inhibition
Authors: Athukuri Bhargavi Latha , Neerati Prasad 
Published: March 2017

Purpose: Domperidone is a commonly used antiemetic drug. The oral bioavailability of domperidone is very low due to its rapid first pass metabolism in the intestine and liver. Piperine, the main alkaloid present in black pepper has been reported to show inhibitory effects on Cytochrome P-450 (CYP-450) enzymes and P-glycoprotein (P-gp). In the present study we investigated the effect of piperine pretreatment on the intestinal transport and oral bioavailability of domperidone in male Wistar rats. Methods: The intestinal transport of domperidone was evaluated by an in-vitro non-everted sac method and in-situ single pass intestinal perfusion (SPIP) study. The oral pharmacokinetics of domperidone was evaluated by conducting oral bioavailability study in rats. Results: A statistically significant improvement in apparent permeability (Papp) was observed in rats pretreated with piperine compared to the respective control group. The effective permeability (Peff) of domperidone was increased in the ileum of the piperine treated group. Following pretreatment with piperine, the peak plasma concentration (Cmax) and area under the concentration- time curve (AUC) were significantly increased. A significant decrease in time to reach maximum plasma concentration (Tmax), clearance and elimination rate constant (Kel) was observed in rats pretreated with piperine. Conclusions: Piperine enhanced the oral bioavailability of domperidone by inhibiting CYP3A1 and P-gp in rats. This observation suggests the possibility that the combination of piperine with other CYP3A4 and P-gp dual substrates may also improve bioavailability. Further clinical studies are recommended to verify this drug interaction in human volunteers and patients. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.