bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parent-based early childhood interventions do make a difference! A rebuttal to See and Gorard (2015a)
Authors: Goldstein Keith , Vatalaro Angela , Yair Gad 
Published: November 2017

Purpose
The purpose of this paper is to refute See and Gorard’s paper published in this journal in 2015 which argues that parent-based interventions for school readiness are ineffective.

Design/methodology/approach
Methods and results from 107 studies that were cited in See and Gorard (2015a) and associated reports were reviewed. Evaluations were made based on comparing the original studies with the summaries of those studies in the publication.

Findings
In this rebuttal, the authors show how See and Gorard erred to correctly report methods, sample sizes, outcomes measured, and the actual results of prior research.

Practical implications
The authors suggest that See and Gorard do not provide solid evidence within their article to back up their claims about parent intervention programs. This rigorous review of See and Gorard’s primary sources reveals that the empirical evidence stands contrary to the claims being made. See and Gorard inaccurately reviewed publications which contradict their conclusions, and they relied on a vast amount of unpublished papers by students to support their claims.

Originality/value
The authors demonstrate how See and Gorard misapplied their own standards of evaluation; the authors claim that their source materials contradict the “finding” they purport to present; and the authors argue that they chose lesser known studies when more reputable ones were available.
The impact of mentoring and pedagogy on mitigation of library stress of undergraduate students
Authors: Alazemi Huwayah M. , Alharbi Awadh 
Published: November 2017

PurposeThis paper aims to justify the relevance of student-centred teaching – learning in influencing their motivation to shed library fear, source resources, attain higher-order learning, garner intellectual prowess and invent new theories.Design/methodology/approachTo assess the validity of association between guidance, pedagogy, library access and intellectual prowess, a close-ended questionnaire is used. This questionnaire was administered on 350 undergraduate students in Kuwait. The step helped to gather their responses and initiate correlation analysis. Also, correlation analysis was used to review the association between the items selected in the questionnaire, interpret outcomes and draw valid inferences.FindingsThe outcome highlights that such students show keen interest to learn when faculty members give credence to educational psychology, teaching-learning quality, knowledge transfer and their transformation into knowledge seekers. The realization of such scholastic capabilities makes it possible for them to shed library fear and search disappointments, circumvent procedural complexities and pay least importance to size of library structure. Such mental state heightens their desire to use library services optimally, learn and contribute to new knowledge.Originality/valueFew attempts have been made to study the impact of mentoring and pedagogy on mitigation of library stress undergraduate students.
How does social sustainability feature in studies of supply chain management? A review and research agenda
Authors: Nakamba Christine Chanda , Chan Paul W. , Sharmina Maria 
Published: November 2017

Purpose
The purpose of this paper is to examine how social sustainability is considered in the study of supply chain management, thereby identifying key areas for future researchers to develop.

Design/methodology/approach
A systematic literature review of 109 studies is conducted. The papers have been analysed with a particular focus on their definition of social sustainability, research methods used, the central themes covered and the evolution of the debate including theories and the main findings.

Findings
Findings show that, first, researchers have thus far focused on principles for managing social change, developing measures for performance, identifying drivers and barriers, with few studies considering the social practices, particularly at the micro level and in the context of small and medium-sized enterprises. Second, findings also reveal that there is less consideration of the suppliers’, as opposed to the buyers’, perspective.

Research limitations/implications
This review focuses only on social sustainability within supply chain management, without considering the economic and environmental dimensions.

Practical implications
This review provides the key themes and areas for managers/practitioners to consider when implementing social sustainability in supply chains. It also provides insights into under-researched areas together with the need for future researchers to move beyond frameworks and develop more tools and instruments for measuring social performance in practice.

Originality/value
This paper is one of the few studies that consider the social dimension of sustainability exclusively within the context of supply chains, providing insights and implications for further research.
New modified selective platinum electrode based on poly (ethylene glycol) for Iron (III) detection in real water
Authors: Mecheri Nacira , Benounis Messaoud , Barhoumi Houcine 
Published: November 2017

PurposeThis work aims to determine iron (III) in real water by using a new amperometric sensor on the basis of polyethylene glycol (PEG) to test and characterize a new modified selective platinum electrode.Design/methodology/approachIn this review, the authors focus on testing and characterizing several polymeric membranes by using cyclic voltammetry and square-wave voltammetry (SWV) methods to differentiate the nature of plasticizers (2-Nitrophenyl octyl ether [NPOE], Di-n-octyl phthalate, Bis (2-ethylhexyl) sebacate, PEG. The authors have evaluated the possibility of using crown ether and three zeolite ionophore (faujasite [FAU], Chabazite and ZSM-5) matrixes as novel materials for the selective determination of iron (III) using SWV for the best membranes.FindingsThe results demonstrated that the modified platinum electrode presents linear dependence of amperometric signal with a wide linear range of 10−9to 10−4mol.L−1for iron determination, revealing a detection limit of 10−10mol.L−1and amperometric sensibility of 58.58 µA/mol.L−1. The slope of the membrane plasticized with PEG calibration curve is six times higher than that of the other membranes. It was noticed that when the crown ether and the three zeolite ionophores were used, as a new detective material for iron with the membrane plasticized with PEG, the expected results were highly proven. The modified platinum electrode showed high selectivity to iron (III) when the heavy metal ions such as Ni (II), Al (III), Zn (III), Cd (II), Gd (II) and Cu (II) were present.Originality/valueThe utility of the method and the efficiency of the best membrane sensor have been accurately tested by the determination of iron in real water samples of Hassi Messaoud, south of Algeria.
Critical disease windows shaped by stress exposure alter allocation trade‐offs between development and immunity
Authors: Kirschman Lucas J. , Crespi Erica J. , Warne Robin W. 
Published: November 2017

AbstractUbiquitous environmental stressors are often thought to alter animal susceptibility to pathogens and contribute to disease emergence. However, duration of exposure to a stressor is likely critical, because while chronic stress is often immunosuppressive, acute stress can temporarily enhance immune function. Furthermore, host susceptibility to stress and disease often varies with ontogeny; increasing during critical developmental windows. How the duration and timing of exposure to stressors interact to shape critical windows and influence disease processes is not well tested.We used ranavirus and larval amphibians as a model system to investigate how physiological stress and pathogenic infection shape development and disease dynamics in vertebrates. Based on a resource allocation model, we designed experiments to test how exposure to stressors may induce resource trade‐offs that shape critical windows and disease processes because the neuroendocrine stress axis coordinates developmental remodelling, immune function and energy allocation in larval amphibians.We used wood frog larvae (Lithobates sylvaticus) to investigate how chronic and acute exposure to corticosterone, the dominant amphibian glucocorticoid hormone, mediates development and immune function via splenocyte immunohistochemistry analysis in association with ranavirus infection.Corticosterone treatments affected immune function, as both chronic and acute exposure suppressed splenocyte proliferation, although viral replication rate increased only in the chronic corticosterone treatment.Time to metamorphosis and survival depended on both corticosterone treatment and infection status. In the control and chronic corticosterone treatments, ranavirus infection decreased survival and delayed metamorphosis, although chronic corticosterone exposure accelerated rate of metamorphosis in uninfected larvae. Acute corticosterone exposure accelerated metamorphosis increased survival in infected larvae.Interactions between stress exposure (via glucocorticoid actions) and infection impose resource trade‐offs that shape optimal allocation between development and somatic function. As a result, critical disease windows are likely shaped by stress exposure because any conditions that induce changes in differentiation rates will alter the duration and susceptibility of organisms to stressors or disease.
The neuronal and endocrine roles of RCAN1 in health and disease
Authors: Peiris Heshan , Keating Damien J. 
Published: November 2017

SummaryThe regulator of calcineurin 1 (RCAN1) was first discovered as a gene located on human chromosome 21, expressed in neurons and overexpressed in the brains of Down syndrome individuals. Increased expression of RCAN1 has been linked with not only Down syndrome‐associated pathology but also an associated neurological disorder, Alzheimer's Disease, in which neuronal RCAN1 expression is also increased. RCAN1 has additionally been demonstrated to affect other cell types including endocrine cells, with links to the pathogenesis of β‐cell dysfunction in type 2 diabetes. The primary functions of RCAN1 relate to the inhibition of the phosphatase calcineurin, and to the regulation of mitochondrial function. Various forms of cellular stress such as reactive oxygen species and hyperglycaemia cause transient increases in RCAN1 expression. The short term (hours to days) induction of RCAN1 expression is generally thought to have a protective effect by regulating the expression of pro‐survival genes in multiple cell types, many of which are mediated via the calcineurin/NFAT transcriptional pathway. However, strong evidence also supports the notion that chronic (weeks‐years) overexpression of RCAN1 has a detrimental effect on cells and that this may drive pathophysiological changes in neurons and endocrine cells linked to Down syndrome, Alzheimer's Disease and type 2 diabetes. Here we review the evidence related to these roles of RCAN1 in neurons and endocrine cells and their relationship to these human health disorders.
Furan Levels and Sensory Profiles of Commercial Coffee Products Under Various Handling Conditions
Authors: Han Jeesoo , Kim Mina K. , Lee Kwang‐Geun 
Published: November 2017

AbstractIn this study, the levels of furan in coffee with consideration towards common coffee consumption was investigated. The concentration of furan in brewed coffee was the highest among the coffee types studied, with an average of 110.73 ng/mL, followed by canned coffee (28.08 ng/mL) and instant coffee (8.55 ng/mL). In instant and brewed coffee, the furan levels decreased by up to an average of 20% and 22%, after 5 min of pouring in a cup without a lid. The degree of reduction was greater when coffee was served without a lid, regardless of coffee type (P < 0.05). In canned coffee, the level of furan decreased by an average of 14% after storage at 60 °C without a lid, and the degree of furan reduction in coffee was greater in coffee served warm (60 °C) than in coffee served cold (4 °C). A time‐dependent intensities of sensory attributes in commercial coffees with various handling condition were different (P < 0.05), suggesting that coffee kept in a cup with lid closed, holds the aroma of coffee longer than coffee in a cup without a lid.Practical ApplicationConsumption of coffee has increased rapidly in Korea over the past few years. Consequently, the probability of exposure to chemical hazards presence in coffee products increases. Furan is a heterocyclic compound, formed mainly from Maillard reaction, therefore present in coffee products. This work demonstrated the strategy to reduce the levels of furan in coffee products at individual consumer level, by investigating the levels of furan served in common handling scenarios of coffee in Korea: canned coffee, instant coffee, and brewed coffee. Findings of this study can practically guide industry, government, and consumer agencies to reduce the risk exposure to furan during coffee consumptions.
Effect of House Cricket (Acheta domesticus) Flour Addition on Physicochemical and Textural Properties of Meat Emulsion Under Various Formulations
Authors: Kim Hyun‐Wook , Setyabrata Derico , Lee YongJae , Jones Owen G. , Kim Yuan H. Brad 
Published: November 2017

AbstractThe objective of this study was to determine the effect of house cricket (Acheta domesticus) flour addition on physicochemical and textural properties of meat emulsion under various formulations. As an initial marker of functionality, protein solubility, water absorption, emulsifying capacity, and gel formation ability of house cricket flour were determined at pH (2 to 10) and NaCl concentrations (0 to 2.10 M). Control emulsion was formulated with 60% lean pork, 20% back fat, and 20% ice. Six treatment emulsions were prepared with replacement of lean pork and/or back fat portions with spray‐dried house cricket flour at 5% and 10% levels, based on a total sample weight. The protein solubility of house cricket flour (67 g protein/100 g) was significantly altered depending upon pH (P < 0.0001) and NaCl concentration (P = 0.0421). Similar water absorption capacity, emulsifying capacity, and gel formation ability of house cricket flour were found between 0 and 2.10 M NaCl concentration (P > 0.05). The replacement of lean meat/fat portion with house cricket flour within 10% level could fortify protein and some micronutrients (phosphorus, potassium, and magnesium) in meat emulsion, without negative impacts on cooking yield and textural properties. Our results suggest that house cricket flour can be used as an effective nonmeat functional ingredient to manufacture emulsified meat products.Practical ApplicationTo better utilize house cricket flour as a food ingredient in wide application, understanding its technological properties in various pH, and ionic strength conditions is a pivotal step. Protein solubility of house cricket flour would be considerably affected by the varying pH and NaCl concentrations of applied conventional foods. In the case of meat emulsion, within 10% lean meat and/or fat portions could be successfully substituted with house cricket flour without detectable adverse impacts on technological properties associated with cooking yield and instrumental analysis of texture. Thus, our findings suggest that house cricket flour possess the necessary physical properties to be used as an alternative nonmeat ingredient for incorporation within emulsified meat products, which could be further explored in subsequent sensory‐based studies.
A standardized workflow for surveying recombinases expands bacterial genome‐editing capabilities
Authors: Ricaurte Deirdre E. , Martínez‐García Esteban , Nyerges Ákos , Pál Csaba , de Lorenzo Víctor , Aparicio Tomás 
Published: November 2017

SummaryBacterial recombineering typically relies on genomic incorporation of synthetic oligonucleotides as mediated by Escherichia coli λ phage recombinase β – an occurrence largely limited to enterobacterial strains. While a handful of similar recombinases have been documented, recombineering efficiencies usually fall short of expectations for practical use. In this work, we aimed to find an efficient Recβ homologue demonstrating activity in model soil bacterium Pseudomonas putida EM42. To this end, a genus‐wide protein survey was conducted to identify putative recombinase candidates for study. Selected novel proteins were assayed in a standardized test to reveal their ability to introduce the K43T substitution into the rpsL gene of P. putida. An ERF superfamily protein, here termed Rec2, exhibited activity eightfold greater than that of the previous leading recombinase. To bolster these results, we demonstrated Rec2 ability to enter a range of mutations into the pyrF gene of P. putida at similar frequencies. Our results not only confirm the utility of Rec2 as a Recβ functional analogue within the P. putida model system, but also set a complete workflow for deploying recombineering in other bacterial strains/species. Implications range from genome editing of P. putida for metabolic engineering to extended applications within other Pseudomonads – and beyond.
Growing the biphasic framework: Techniques and recommendations for fitting emerging growth models
Authors: Wilson Kyle L. , Honsey Andrew E. , Moe Brian , Venturelli Paul 
Published: November 2017

Abstract

Several new growth models have been proposed to account for the life‐history trade‐offs that occur when indeterminately growing species allocate energy between somatic growth and reproduction. These models can improve the understanding of lifetime growth and life history, but can be more difficult to fit than conventional growth models. Increased data demands, multiple growth phases and increased parameterization all serve as barriers to the adoption and proper use of these new models.

We review and comment on confounding issues during model fitting for several of these models, and provide advice on surmounting such issues. We then simulation‐test an example model, the Lester biphasic growth model, using several common fitting approaches. We highlight the biases and precision of each approach and provide guiding documents using r and jags code.

The Bayesian Markov chain Monte Carlo and likelihood profiling approaches generally provided the best fits. Simpler approaches can be unbiased and precise if sampled data are of relatively high quality (e.g. moderate sample sizes for juvenile and adult phases) and model assumptions are met. Bayesian hierarchical approaches can accommodate more complicated data scenarios (e.g. unbalanced design across multiple populations); we provide an example of such an approach by recovering growth trajectories and inferring growth‐associated trait variation and environmental effects across multiple populations.

Conventional growth models provide limited inference on life history. Many biphasic growth models can provide direct inference on multiple life‐history traits, but can be difficult to fit. The recommended approaches herein provide a path forward for fitting biphasic growth models in a variety of scenarios, allowing for wider application and tests of life history and ecological theory.
Prospective study on long‐term outcome after abdominal surgery
Authors: Brynjarsdottir E. D. , Sigurdsson M. I. , Sigmundsdottir E. , Möller P. H. , Sigurdsson G. H. 
Published: November 2017

BackgroundComplications following major abdominal surgery are common and an important cause of morbidity and mortality. The aim of this study was to describe 1‐year mortality and identify factors that influence adverse outcomes after abdominal surgery.MethodsThis prospective observational cohort study was performed in Landspitali University Hospital and included all adult patients undergoing abdominal surgery requiring > 24‐h hospital admission over 13 months. The follow‐up period was 60 days for complications and 24 months for mortality.ResultsData were available for 1113 (99.5%) of the 1119 patients who fulfilled inclusion criteria. A total of 23% of patients had at least one underlying co‐morbidity. Non‐elective surgeries were 48% and 13% of the patients were admitted to ICU post‐operatively. A total of 20% of patients developed complications. Mortality at 30 days, 1 and 2 years was 1.8%, 5.6%, and 8.3% respectively. One‐year mortality for those admitted to ICU was 18%. The long‐term survival of the individuals surviving 30 days was significantly worse than for an age‐ and gender‐matched population control group. Independent predictors for 1‐year mortality were age, pre‐operative acute kidney injury and intermediate‐ or major surgery.ConclusionPost‐operative complication rates and mortality following abdominal surgery in Iceland were comparable or in the lower range of previously published outcomes, validating the utility of offering a full host of abdominal surgical services in geographically isolated region with a relatively small referral base.
Amyloid Beta monomers regulate cyclic adenosine monophosphate response element binding protein functions by activating type‐1 insulin‐like growth factor receptors in neuronal cells
Authors: Zimbone Stefania , Monaco Irene , Gianì Fiorenza , Pandini Giuseppe , Copani Agata G. , Giuffrida Maria Laura , Rizzarelli Enrico 
Published: November 2017

SummaryAlzheimer's disease (AD) is a progressive neurodegenerative disorder associated with synaptic dysfunction, pathological accumulation of β‐amyloid (Aβ), and neuronal loss. The self‐association of Aβ monomers into soluble oligomers seems to be crucial for the development of neurotoxicity (J. Neurochem., 00, 2007 and 1172). Aβ oligomers have been suggested to compromise neuronal functions in AD by reducing the expression levels of the CREB target gene and brain‐derived neurotrophic factor (BDNF) (J. Neurosci., 27, 2007 and 2628; Neurobiol. Aging, 36, 2015 and 20406 Mol. Neurodegener., 6, 2011 and 60). We previously reported a broad neuroprotective activity of physiological Aβ monomers, involving the activation of type‐1 insulin‐like growth factor receptors (IGF‐IRs) (J. Neurosci., 29, 2009 and 10582, Front Cell Neurosci., 9, 2015 and 297). We now provide evidence that Aβ monomers, by activating the IGF‐IR‐stimulated PI3‐K/AKT pathway, induce the activation of CREB in neurons and sustain BDNF transcription and release.