bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE DEVELOPMENT OF MARINE SPATIAL PLANNING AND ITS APPLICATION FOR FLOATING FISH NET CULTURE
Authors: Sutrisno Dewayany 
Published: March 2017

Marine spatial planning has become the crucial issues for an archipelagic state such as Indonesia. The global market demand on marine economic species has been initiated the exploitation of the marine species which will become the hindrance in maintaining the sustainable marine biodiversity. Besides that, the degradation of marine species will also become the problem for traditional fishermen. Therefore, a model has to be employed to spatially manage the coastal waters as the alternative for fishermen activities during closed seasons, such as floating fish net culture. The aim of this study was to develop marine spatial planning model based on ecological approach in order to identify the potentiality of marine waters for marine culture such as floating fish net culture. The method for the model consisted of social assessment using the Delphi for developing the rule of marine planning for floating fish net culture and the spatial analysis technique for determining the model of marine spatial planning for floating fish net culture. The area of Kupang Bay waters, East Nusa Tenggara was used as the study area. The result indicated that the model can be used to sustainable marine spatial planning, especially for floating fish net culture. The model considered the aspects of potential area for marine culture, the management of zonation and transportation lanes, the conservation and protected area and the strategic area. Application in Kupang bay illustrated the aspect of technology input such as raceways since the majority of the area of Kupang Bay waters is classified as medium potential. Further research still needs to optimum the application of model to others marine area.
Evaluasi Implementasi Masterplan Kawasan Agropolitan Ciwidey Menggunakan Logic Models
Authors: Agustina Isnaeni , Artiningsih A. 
Published: March 2017

The rural development should be encouraged to reduce inequalities in urban and rural areas, including through the program of agropolitan area development. The government of Bandung District has compiled the Masterplan of Agropolitan Ciwidey in 2007, implemented in 2008-2012, and evaluated in 2013-2016. This study aims to find out the performance of the Ciwidey’s agropolitan development programs and activities. The study was conducted using logic models analysis that describes the input, output, outcome, and impact on a diagram and then described using causality description. The findings address that the development program of Ciwidey agropolitan has the positive impacts for physical and social characteristics, while it has adverse effects for economic characteristics. This study recommends that the robust support from the institutional of agribusiness activity is needed to develop an agropolitan area.
Novel immunoassays for detection of CUZD1 autoantibodies in serum of patients with inflammatory bowel diseases
Authors: Farkona Sofia , Soosaipillai Antoninus , Filippou Panagiota , Liaskos Christos , Bogdanos Dimitrios P. , Diamandis Eleftherios P. , Blasutig Ivan M. 
Published: March 2017

AbstractBackground:Pancreatic autoantibodies (PABs) are detected in patients with inflammatory bowel disease (IBD). Their prevalence is higher in Crohn’s disease (CrD) than in ulcerative colitis (UC). Glycoprotein 2 (GP2) and, more recently, CUB and zona pellucida-like domain-containing protein 1 (CUZD1) have been identified as target autoantigens of PAB. The clinical utility of CUZD1 autoantibodies has only recently been assessed by indirect immunofluorescence (IIF) assays. In this study, we developed and validated novel immunoassays for the detection of CUZD1 autoantibodies.Methods:Recombinant CUZD1 protein was utilized as a solid-phase antigen for the development of two immunoassays for the detection of IgG and IgA CUZD1 autoantibodies. Serum samples from 100 patients with CrD, 100 patients with UC, 129 patients assessed for various autoimmune diseases (vADs) and 50 control individuals were analyzed.Results:Two immunofluorometric assays for the detection of IgG and IgA CUZD1-specific antibodies were developed. CUZD1 autoantibodies were detected in 12.5% (25/200) IBD patients, including 16% of patients with CrD and in 9% of patients with UC (CrD vs. UC, p<0.05), compared with 3.1% (4/129) patients suspected of having vADs (CrD vs. ADs, p<0.05; UC vs. ADs, p=0.08). CUZD1 autoantibody positivity was not found to be related to disease location, age of disease onset or disease phenotype.Conclusions:This is the first study to describe novel IgA and IgG CUZD1 autoantibody enzyme-linked immunosorbent assay. These immunoassays agree well with standard IIF techniques and can be utilized in multicenter studies to investigate the diagnostic and clinical utility of CUZD1 autoantibodies.
The Effect of a Dissipative Ladle Shroud on Mixing in Tundish: Mathematical and Experimental Modelling
Authors: Zhang Jiangshan , Yang Shufeng , Li Jingshe , Tang Haiyan , Jiang Zhengyi 
Published: March 2017

AbstractThe effect of a dissipative ladle shroud (DLS) on mixing in tundish was investigated, compared with that of a conventional ladle shroud (CLS) using mathematical and physical modelling. The tracer profiles of mathematical results, achieved using large eddy simulation, were validated by physical observations employing high-speed cinephotography. The design of a DLS dramatically changed the flow patterns and contributed the intermixing of fluid elements inside the ladle shroud. The vortex flow encouraged the turbulent mixing and was verified by tracking of physical tracer dispersion inside the DLS. Residence Time Distribution (RTD) curves were obtained in two different sized tundishes to examine the mixing behaviours. The findings indicated that the DLS benefited the tundish mixing in terms of increasing active volume. The effect seemed to be more remarkable in the smaller tundish. The DLS gave rise to a more plug-like flow pattern inside the tundish, showing potential to shorten the transition length during grade change.
A Quantitative Concordance Measure for Comparing and Combining Treatment Selection Markers
Authors: Zhang Zhiwei , Ma Shujie , Nie Lei , Soon Guoxing 
Published: March 2017

AbstractMotivated by an HIV example, we consider how to compare and combine treatment selection markers, which are essential to the notion of precision medicine. The current literature on precision medicine is focused on evaluating and optimizing treatment regimes, which can be obtained by dichotomizing treatment selection markers. In practice, treatment decisions are based not only on efficacy but also on safety, cost and individual preference, making it difficult to choose a single cutoff value for all patients in all settings. It is therefore desirable to have a statistical framework for comparing and combining treatment selection markers without dichotomization. We provide such a framework based on a quantitative concordance measure, which quantifies the extent to which higher marker values are predictive of larger treatment effects. For a given marker, the proposed concordance measure can be estimated from clinical trial data using a U-statistic, which can incorporate auxiliary covariate information through an augmentation term. For combining multiple markers, we propose to maximize the estimated concordance measure among a specified family of combination markers. A cross-validation procedure can be used to remove any re-substitution bias in assessing the quality of an optimized combination marker. The proposed methodology is applied to the HIV example and evaluated in simulation studies.
Evaluation of Reactive Power Support and Loss Allocation in a Pool Based Competitive Electricity Market
Authors: Moger Tukaram , Dhadbanjan Thukaram 
Published: March 2017

Abstract
This paper presents a new approach using modified Y-bus matrix to compute the reactive power support and loss allocation in a pool based competitive electricity market. The inherent characteristic of the reactive power in system operation is properly addressed in the paper. A detailed case study on a 11-bus equivalent system is carried out to illustrate the effectiveness of the proposed approach. It is also tested on a large 259-bus equivalent system of Indian western region power grid. A comparison is also made with other existing approaches in the literature to highlight the features of the proposed approach. Simulation results show that the reactive power support and loss allocation from the proposed approach is carried out in a systematic manner which takes into consideration the power demand and the relative location of the nodes in the network.
Student-Directed Video Validation of Psychomotor Skills Performance: A Strategy to Facilitate Deliberate Practice, Peer Review, and Team Skill Sets
Authors: DeBourgh Gregory A. , Prion Susan K. 
Published: March 2017

AbstractBackgroundEssential nursing skills for safe practice are not limited to technical skills, but include abilities for determining salience among clinical data within dynamic practice environments, demonstrating clinical judgment and reasoning, problem-solving abilities, and teamwork competence. Effective instructional methods are needed to prepare new nurses for entry-to-practice in contemporary healthcare settings.MethodThis mixed-methods descriptive study explored self-reported perceptions of a process to self-record videos for psychomotor skill performance evaluation in a convenience sample of 102 pre-licensure students.ResultsStudents reported gains in confidence and skill acquisition using team skills to record individual videos of skill performance, and described the importance of teamwork, peer support, and deliberate practice.ConclusionAlthough time consuming, the production of student-directed video validations of psychomotor skill performance is an authentic task with meaningful accountabilities that is well-received by students as an effective, satisfying learner experience to increase confidence and competence in performing psychomotor skills.
A non-invasive method to rule out transient tachypnea of the newborn (TTN): fetal pulmonary artery acceleration to ejection time ratio
Authors: Büke Barış , Akkaya Hatice 
Published: March 2017

AbstractObjective:To investigate whether fetal pulmonary artery acceleration to ejection time (PATET) ratio can predict or rule out subsequent diagnosis of transient tachypnea of the newborn (TTN).Methods:This prospective cohort study included 105 pregnant women in labor, who met the inclusion criteria. Eighteen of these women were removed from the study cohort, because of an inability to acquire sufficient Doppler waveforms and a longer duration of deliveries. According to subsequent diagnosis of TTN in the neonate, the two groups were constituted, TTN+ and TTN−.Results:There were no statistically significant differences between the groups regarding maternal obstetric and demographic features. The neonatal intensive care unit (NICU) submission rate was significantly higher in the TTN+ group (100%, 17%, P<0.0001, respectively). Regarding the fetal pulmonary artery Doppler findings, PATET ratio in the TTN+ group was significantly lower than the TTN− group (0.307 vs. 0.389, P<0.0001, respectively). The PATET ratio and diagnosis of TTN were inversely correlated (r=−0.41, P<0.001), even if adjusted for birth weight, gestational age and fetal gender (r=0.42, P=0.0021). The cut-off value of 0.319 provided 82.7% specificity, 83.3% sensitivity, 96% negative predictive value and 41.6% positive predictive value. Additionally intraobserver ICC for PATET was found to be 0.86.Conclusion:The fetal PATET ratio seems to serve as a promising tool to rule out subsequent diagnosis of TTN.
Access to Scholarly Research Information in Sub-Saharan Africa: A Review
Authors: Malapela Thembani 
Published: March 2017

AbstractSince the year 2000, the world has witnessed an increased call for improved access to scholarly information. The cost of scholarly content is a major barrier in accessing needed research information. In order to fully contribute to the global knowledge economy, African scholars need to access both global information resources and locally published works. Few studies have focused on the African knowledge production vis-à-vis access to scholarly research information in Africa. This paper examines access to scholarly research information in sub-Saharan Africa. The review focuses on available published works on access to scientific literature in Africa and seeks to understand Africa’s scholarly publishing scene. In the process, challenges and opportunities regarding access to scholarly research information are explored. Three approaches in addressing these issues emerge in literature – namely (i) open access, (ii) donor-funded schemes and (iii) negotiated access schemes for scholarly content. This review shows that these approaches have leveraged information access to the African researchers who now have almost the same levels of access to scientific literature as their peers in the developed world. African governments, institutions, researchers and librarians still need to exploit the potential of open access. There remain, however, infrastructural issues that need to be addressed to ensure that the African scholar enjoys access to current scientific information.
Molecular dynamics simulations of hexopyranose ring distortion in different force fields
Authors: Plazinski Wojciech , Plazinska Anita 
Published: March 2017

Abstract
The four classical, biomolecular force fields designed to study hexopyranose-based carbohydrates (GROMOS 56a6CARBO/56a6CARBO_R, GROMOS 53a6GLYC, CHARMM and GLYCAM06) have been tested in the context of ring-inversion properties. These properties were evaluated for both unfunctionalized monomers of all hexopyranoses of the d series and for residues in a chain composed of uniform units connected by α(1→4) and β(1→4) glycosidic linkages. The results indicate that the tested force fields differ in their predictions of the ring-inversion properties of both monomers and residues in a chain. The comparison with the available experimental data and with the semi-empirical Angyal scheme reveals that, at the level of monomers, GROMOS 56a6CARBO, GROMOS 53a6GLYC and CHARMM correctly reproduce the ring-inversion free energies. However, due to the lack of analogous reference data we cannot state which force field is more or less accurate in the context of ring distortion of residues in a chain. Therefore, the use of ab initio potentials is recommended in the prospective, quantitative studies on the related subject.
Characterization of Thermochemically Surface-Hardened Titanium by Light Optical Microscopy
Authors: Gammeltoft-Hansen Niklas , Munch Steffen S. , Jellesen Morten S. , Somers Marcel A. J. , Christiansen Thomas L. 
Published: March 2017

Abstract
Thermochemically treated titanium grades 2 and 5 were investigated by light optical microscopy and hardness indentation. Gaseous oxidation in oxygen and N2O containing atmospheres resulted in a diffusion zone of oxygen in solid solution in titanium with a hardness up to 1000 HV. A surface scale consisting of oxide can be present depending on the treatment conditions. A new type of carbo-oxidation treatment was applied, where carbon and oxygen are simultaneously incorporated into the surface. This resulted in new microstructural features such as a deep zone of mixed interstitial solid solution, i.e., a diffusion zone, and surface regions consisting of a mixed interstitial compound (TiCXO1 − X structure). Carbo-oxidation yields hardness values in excess of 2500 HV in the mixed interstitial compound and values up to 1500 HV in the diffusion zone. Simultaneously, with the surface hardening treatment, core hardening of the material can be obtained.
Using kisspeptin to assess GnRH function in an unusual case of primary amenorrhoea
Authors: Vimalesvaran S , Narayanaswamy S , Yang L , Prague J K , Buckley A , Miras A D , Franks S , Meeran K , Dhillo W S 
Published: March 2017

Summary
Primary amenorrhoea is defined as the failure to commence menstruation by the age of 15 years, in the presence of normal secondary sexual development. The potential causes of primary amenorrhoea extend from structural to chromosomal abnormalities. Polycystic ovarian syndrome (PCOS) is a common cause of secondary amenorrhoea but an uncommon cause of primary amenorrhoea. An early and prompt diagnosis of PCOS is important, as up to 30% of these women are predisposed to glucose intolerance and obesity, with the subgroup of women presenting with primary amenorrhoea and PCOS displaying a higher incidence of metabolic dysfunction. We describe a case of an 18-year-old female presenting with primary amenorrhoea of unknown aetiology. Although initial investigations did not demonstrate clinical or biochemical hyperandrogenism or any radiological evidence of polycystic ovaries, a raised luteinising hormone (LH) suggested a diagnosis of PCOS. If PCOS was the correct diagnosis, then one would expect intact hypothalamic GnRH and pituitary gonadotropin release. We used the novel hormone kisspeptin to confirm intact hypothalamic GnRH release and a GnRH stimulation test to confirm intact pituitary gonadotroph function. This case highlights that kisspeptin is a potential unique tool to test GnRH function in patients presenting with reproductive disorders.

Learning points:

Polycystic ovarian syndrome (PCOS) can present with primary amenorrhoea, and therefore, should be considered in the differential diagnosis.

PCOS is a heterogeneous condition that may present in lean women with few or absent signs of hyperandrogenism.

GnRH stimulation tests are useful in evaluating pituitary function; however, to date, we do not have a viable test of GnRH function. Kisspeptin has the potential to form a novel diagnostic tool for assessing hypothalamic GnRH function by monitoring gonadotropin response as a surrogate marker of GnRH release.

Confirmation of intact GnRH function helps consolidate a diagnosis in primary amenorrhoea and gives an indication of future fertility.
Breastfeeding, Cognitive and Noncognitive Development in Early Childhood: A Population Study
Authors: Girard Lisa-Christine , Doyle Orla , Tremblay Richard E. 
Published: March 2017

BACKGROUND AND OBJECTIVES:
There is mixed evidence from correlational studies that breastfeeding impacts children’s development. Propensity score matching with large samples can be an effective tool to remove potential bias from observed confounders in correlational studies. The aim of this study was to investigate the impact of breastfeeding on children’s cognitive and noncognitive development at 3 and 5 years of age.

METHODS:
Participants included ∼8000 families from the Growing Up in Ireland longitudinal infant cohort, who were identified from the Child Benefit Register and randomly selected to participate. Parent and teacher reports and standardized assessments were used to collect information on children’s problem behaviors, expressive vocabulary, and cognitive abilities at age 3 and 5 years. Breastfeeding information was collected via maternal report. Propensity score matching was used to compare the average treatment effects on those who were breastfed.

RESULTS:
Before matching, breastfeeding was associated with better development on almost every outcome. After matching and adjustment for multiple testing, only 1 of the 13 outcomes remained statistically significant: children’s hyperactivity (difference score, –0.84; 95% confidence interval, –1.33 to –0.35) at age 3 years for children who were breastfed for at least 6 months. No statistically significant differences were observed postmatching on any outcome at age 5 years.

CONCLUSIONS:
Although 1 positive benefit of breastfeeding was found by using propensity score matching, the effect size was modest in practical terms. No support was found for statistically significant gains at age 5 years, suggesting that the earlier observed benefit from breastfeeding may not be maintained once children enter school.
Las políticas de evaluación universitaria en Argentina: balance y desafíos
Authors: Nosiglia María Catalina , Mulle Verónica 
Published: March 2017

La evaluación educativa fue una de las políticas más sobresaliente de la década de los ´90 en Argentina. Esta temática estuvo presente en la agenda de las políticas neoliberales de todos los niveles educativos, asociada a una cuestión más amplia: la preocupación por la calidad de la educación. Las orientaciones políticas en esta materia suponían la necesidad de competencia interinstitucional, la mayor responsabilidad de las instituciones y los docentes por los resultados y la rendición de cuentas como mecanismos para garantizarla.En el nivel universitario en Argentina, la introducción de los mecanismos de evaluación institucional y la acreditación de carreras de grado y posgrado fueron establecidos en 1995 a partir de la Ley de Educación Superior N° 24.521 (LES).El objetivo de este trabajo es presentar algunas reflexiones sobre las tensiones de las políticas de evaluación universitaria, distinguiendo analíticamente cuatro cuestiones que atraviesan este campo y que plantean relaciones complejas: evaluación y autonomía, evaluación y planeamiento, evaluación y calidad, evaluación y pertinencia social. Asimismo, se incluyen algunas características de la conformación del campo de la evaluación y acreditación universitaria en Argentina, haciendo especial referencia al caso de la Universidad de Buenos Aires. Finalmente, se plantean consideraciones para futuras investigaciones y revisiones de esta política, tras dos décadas de implementación
Intención de uso de la tecnología biométrica en el sector financiero: efecto de la utilidad sobre los riesgos percibidos por el consumidor
Authors: Soto Beltrán Laura Lorena 
Published: March 2017

<p>Mediante un análisis de revisión sistemática de literatura, se evidenció que existen múltiples riesgos percibidos por el consumidor asociados al uso de las tecnologías biométricas, los cuales son la mayor barrera de entrada de esta tecnología, principalmente en los entornos financieros. Dado que no se han realizado estudios que evalúen si la utilidad de la misma y sus beneficios son mayores a los riesgos percibidos por el consumidor, el presente estudio busca medir la intención de uso de las tecnologías biométricas en entornos financieros y evaluar si la utilidad de la tecnología es mayor a los riesgos percibidos, para así y según los resultados obtenidos, realizar las recomendaciones a las entidades que aplicarán estas tecnologías a fin de facilitar su adopción por parte sus clientes o proponer modificaciones a las mismas para adaptarlas a las necesidades del consumidor y de las entidades. </p>
Barreras de gestión de marketing para la prestación del servicio niños diabéticos Tipo I desde la perspectiva de docentes en instituciones educativas en Bogotá
Authors: Espinosa Tobon Veronica 
Published: March 2017

<p>La siguiente investigación tiene como propósito identificar las barreras de gestión del marketing para la prestación del servicio de niños diabéticos tipo 1, desde la perspectiva de docentes en colegios de la ciudad de Bogotá, analizando la importancia de los elementos del marketing mix dentro de la gestión de marketing, tales como, alianzas estratégicas, personas, procesos, así como la comunicación de información efectiva para este grupo objetivo, que permita identificar las falencias o fortalezas de las mismas, para en un futuro mejorar el servicio y consecuentemente mejorar la calidad de vida de este segmento de la población. Se pretende a través de una investigación cualitativa, trasversal y multicéntrico con técnica de muestreo de bola de nieve, indagar los conocimientos que sobre la enfermedad y su manejo poseen estos actores importantes dentro de la vida de los niños diabéticos tipo 1, estableciendo la relación directa con los elementos del marketing mix mencionados, para de esta forma generar conocimiento que permita el planteamiento de futuros proyectos en pro de mejorar la calidad de vida de este grupo de la población. </p>