bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of SARS-CoV-2 variants related mutations in wastewater using RT-qPCR and variant-specific probes in Porto Alegre, Southern Brazil
Authors: Mangini Arthur Tonietto , Prandi Bruno Aschidamini , Violet-Lozano Lina , Cunha Pâmela Ferreira , Jarenkow Andre , Campos Aline Alves Scarpellini , Pasqualim Gabriela , Hartke Sara , Brum da Silva Ilma Simoni , Campos Fabrício Souza , Roehe Paulo Michel , Franco Ana Cláudia 
Published: October 2024

ABSTRACT

The COVID-19 pandemic has underscored the significance of monitoring genetic variations in pathogenic viruses to manage its transmission and identify emerging variants. Nonetheless, sequencing every positive patient case is impractical for large-scale testing of the population. Here, we introduce a cost-effective tool for identifying SARS-CoV-2 mutations associated with variants in wastewater. This approach relies on a wastewater surveillance system and reverse transcription-quantitative polymerase chain reaction (RT-qPCR), utilizing mutation-specific probes. Wastewater samples were analyzed for SARS-CoV-2 mutations corresponding to variants under monitoring (VUM) (P.2, alpha, beta, gamma, delta, and omicron) as part of a wastewater-based SARS-CoV-2 monitoring program. Our findings validate the efficacy of this method in detecting SARS-CoV-2 mutations linked to variants in wastewater, facilitating early detection of emerging variants and informing decision-making on control measures.
Contextual and psychological factors in using recycled stormwater for residential purposes: a case study from Taiyuan, China
Authors: Guo Shufen , Wu Zhifang , Keremane Ganesh 
Published: October 2024

ABSTRACT
This paper reviewed the managed aquifer recharge (MAR) practices around the world and explored urban residents' attitudes towards using stormwater recycled through MAR for residential uses in a Chinese socio-cultural context. The exploration was conducted from both contextual and psychological perspectives based on two established theories. The moderating effect of gender on residents' attitudes was tested. The results showed that most respondents supported using recycled stormwater for residential purposes but demonstrated hesitance in using recycled stormwater for uses that present proximity to human contact, which normally requires connecting the water to their house. Regarding the water quality attributes such as the colour, odour, and salt content of recycled stormwater, respondents were more tolerant if the water was used for uses that have limited human contact and less tolerant for uses that have close human contact. Therefore, any future decision to connect recycled stormwater into houses would require careful consideration and investigation as it depends on a range of issues including the proximity to human contact and the quality attributes of the water. Gender was a weak predictor in moderating respondents' attitudes towards using recycled stormwater, which adds to the inconsistent literature.
Fully automated simplification of urban drainage models on a city scale
Authors: Pichler Markus , König Albert Wilhelm , Reinstaller Stefan , Muschalla Dirk 
Published: October 2024

ABSTRACT

The article presents an innovative method for simplifying urban drainage models. This approach strategically reduces complexity while preserving accuracy in large-scale, high-resolution models such as those of the city of Graz. It involves the selective removal and aggregation of sewer network elements like subcatchments and conduits, ensuring vital features like storage nodes and flow controls remain intact for precise simulations. Despite significant reductions in model components, the simplified version maintains high accuracy in hydrological and hydraulic aspects, including water balance components like infiltration loss, surface runoff, and external outflow. The method proves equally effective across both land cover and sewer shed-based models, offering computational efficiencies that speed-up processing by 20–45 times for the study site. This is particularly beneficial for rapid decision-making and resource optimization in urban planning. The model also adeptly predicts flood events, especially from larger, infrequent rainfall, although an overly restrictive flow capacity can refine flood predictions at the expense of other flow characteristics. Ultimately, this streamlined approach allows for the quick creation of simplified, yet accurate, models from high-resolution city-scale hydrodynamic data or digital twins, facilitating efficient and timely analyses in urban drainage management.
Simulation of the response of a magnetic polymersome in an inhomogeneous magnetic field
Authors: Ryzhkov A. V. 
Published: October 2024

Purpose. Identification of the behavior of a magnetic polymersome placed in an inhomogeneous field of a point dipole using coarse-grained molecular dynamics simulations.Methods. The system under the study is represented as a set of interacting particles of two types: polymeric particles simulating a double layer of an amphiphilic membrane, and magnetic nanoparticles located in the membrane layer. Polymeric particles interact through elastic potentials designed to maintain an equilibrium spherical vesicular geometry. Magnetic nanoparticles interact with each other and external fields as point dipoles. The excluded volume and steric interaction of magnetic particles with polymeric walls are modeled in the form of soft repulsion. The entire system is under isothermal conditions, and the model parameters are chosen according to typical interaction energies relative to thermal fluctuations. A model polymersome with a diameter of about 100 nm in an aqueous solution at 25°C is considered. An inhomogeneous magnetic field is created by a dipole of constant direction located at a fixed distance. The dynamics of the system is monitored by numerical solution of the equations of particles motion with introduced interactions and imposed conditions.Results. In numerical experiments, the response of the polymersome to a magnetic field was obtained for three values of the parameter describing the inhomogeneity of the field. The problem with a gradual increase in the strength (and its gradient) of the magnetic field near the polymersome is considered. Changes in the magnetization of the system are shown, and the redistribution of the concentration of nanoparticles is analyzed. A simulation of the situation when the center of the polymersome at the initial moment was placed at a point with a fixed value of the magnetic field for three cases of inhomogeneity of the field was carried out. A significant restructuring of the magnetic layer of the vesicle combined with movement of the entire capsule was detected. Estimates are made about the average velocity based on the displacement of the object.Conclusion. The model allows to evaluate the features of the combined magnetic, structural and mechanical response of the polymersome to an inhomogeneous field in the context of potential applications for controlled delivery of contents into cells.
Mechanical properties of silicone polymer with magnetic filler in magnetic field
Authors: Sutarina I. Y. , Novikov K. K. , Sokolov E. A. , Matarykin K. A. , Rjapolov P. A. 
Published: October 2024

Purpose. To investigate the change in the mechanical properties of a magnetorheological silicone elastomer consisting of a polymer filled with magnetite nanoparticles under the influence of an inhomogeneous magnetic field of an electromagnet. Methods. The experiments were carried out on a magnetic response research facility developed and manufactured independently based on known methods. The value of the deflection angle of the magnetically active receiver was determined by the optical method. Two-component silicone rubbers filled with magnetite particles were studied as samples. The manufactured samples differed in geometric dimensions, magnetic phase concentrations of 1%, 5%, 10% and 20%, and polymerization mechanism. The source of the magnetic field was electromagnets of various sizes connected to power sources. The images were captured using a Micmed 5.0 digital USB microscope.Results. The analysis of the structure of the manufactured magnetorheological silicone elastomers was carried out, as well as studies of the effect of the magnetic field strength and sample parameters on the deflection angle of the magnetically active cantilever. A theoretical interpretation of the obtained results is proposed.Conclusion. The experimental dependence of the tilt angle of a magnetically active polymer cantilever on the equilibrium position relative to the magnitude of the magnetic field strength of the electromagnet is determined. The obtained research results can be used to develop actuators and magnetoactive sensors.
Production and research of tungsten carbide powder from VA grade tungsten metal waste in aviation kerosene
Authors: Ageeva E. V. , Lоktionova O. G. , Ulitin D. A. , Ageeva A. E. 
Published: October 2024

Purpose. Obtaining and studying the composition, structure and properties of tungsten carbide powder from VA grade tungsten metal waste in aviation kerosene. Methods. Tungsten carbide powder from tungsten metal waste of the VA brand was obtained in the following sequence. The reactor was filled with a working medium – aviation kerosene of the TS-1 brand, the waste was loaded into the reactor. Electrodes were mounted from the same waste tungsten of the VA brand. The mounted electrodes were connected to a pulse generator. The necessary electrical parameters of the installation were set: the capacitance of the condensers is 42.0–43.5 UF; the voltage on the electrodes is from 115–120 V; the pulse repetition rate is 50–55 Hz. The resulting tungsten powder was studied using: a scanning electron microscope QUANTA 600 FEG; a particle size analyzer Analysette 22 NanoTec; an energy-dispersed X-ray analyzer from the company EDAX; X-ray diffraction on a diffractometer Rigaku Ultima IV. Results. Based on the conducted experimental studies, a new method for producing tungsten carbide powder has been developed, characterized in that the powder is obtained by electroerosive dispersion of tungsten metal waste of the VA brand in aviation kerosene at a capacitor capacity of 42.0–43.5 UF, an electrode voltage of 115–120 V and a pulse repetition frequency of 50–55 Hz. It has been experimentally established that spherical and elliptical particles of tungsten carbide powder W2C have sizes from 2.26 microns to 90.72 microns with an average volumetric diameter of 20.2 microns and contain carbon on the surface. Conclusion. The production of tungsten carbide suitable for industrial use at low energy costs from metal waste has shown high efficiency of the technology of electroerosion dispersion.
Practical Recommendations for Navigating Digital Tools in Hospitals: Qualitative Interview Study
Authors: Wosny Marie , Strasser Livia Maria , Kraehenmann Simone , Hastings Janna 
Published: October 2024

Background
The digitalization of health care organizations is an integral part of a clinician’s daily life, making it vital for health care professionals (HCPs) to understand and effectively use digital tools in hospital settings. However, clinicians often express a lack of preparedness for their digital work environments. Particularly, new clinical end users, encompassing medical and nursing students, seasoned professionals transitioning to new health care environments, and experienced practitioners encountering new health care technologies, face critically intense learning periods, often with a lack of adequate time for learning digital tools, resulting in difficulties in integrating and adopting these digital tools into clinical practice.

Objective
This study aims to comprehensively collect advice from experienced HCPs in Switzerland to guide new clinical end users on how to initiate their engagement with health ITs within hospital settings.

Methods
We conducted qualitative interviews with 52 HCPs across Switzerland, representing 24 medical specialties from 14 hospitals. The interviews were transcribed verbatim and analyzed through inductive thematic analysis. Codes were developed iteratively, and themes and aggregated dimensions were refined through collaborative discussions.

Results
Ten themes emerged from the interview data, namely (1) digital tool understanding, (2) peer-based learning strategies, (3) experimental learning approaches, (4) knowledge exchange and support, (5) training approaches, (6) proactive innovation, (7) an adaptive technology mindset, (8) critical thinking approaches, (9) dealing with emotions, and (10) empathy and human factors. Consequently, we devised 10 recommendations with specific advice to new clinical end users on how to approach new health care technologies, encompassing the following: take time to get to know and understand the tools you are working with; proactively ask experienced colleagues; simply try it out and practice; know where to get help and information; take sufficient training; embrace curiosity and pursue innovation; maintain an open and adaptable mindset; keep thinking critically and use your knowledge base; overcome your fears, and never lose the human and patient focus.

Conclusions
Our study emphasized the importance of comprehensive training and learning approaches for health care technologies based on the advice and recommendations of experienced HCPs based in Swiss hospitals. Moreover, these recommendations have implications for medical educators and clinical instructors, providing advice on effective methods to instruct and support new end users, enabling them to use novel technologies proficiently. Therefore, we advocate for new clinical end users, health care institutions and clinical instructors, academic institutions and medical educators, and regulatory bodies to prioritize effective training and cultivating technological readiness to optimize IT use in health care.
Una revisión actualizada sobre los factores de riesgo y características genéticas asociadas a la trombosis venosa profunda
Authors: García Ortega Sebastián 
Published: October 2024

Introducción:
La TVP es una de las patologías vasculares más comunes en el mundo, cuya aparición es una combinación de diferentes factores de riesgo tanto genéticos como no genéticos, por lo que se considera una enfermedad prevenible, sin embargo, en la actualidad la identificación de estos factores puede representar un desafío para el clínico, lo que lleva a que esta sea clasificada como no provocada o idiopática. Este artículo tiene como objetivo hacer una revisión sobre los factores de riesgo, tanto genéticos como no genéticos que puedan orientar al clínico en la sospecha y prevención de la TVP.

Metodología:
Se realizó una revisión de la literatura en las bases de datos PubMed y Elsevier con el propósito de recopilar información actualizada sobre los factores de riesgo y características genéticas asociadas a la trombosis venosa profunda (TVP). Se emplearon los términos DeSC de trombosis de vena profunda, trombosis venosa y flebotrombosis juntos con sus equivalencias en MeSH, combinadas con los conectores booleanos AND y OR para refinar la búsqueda. Se revisaron un total de 80 artículos publicados entre 2018 y 2023, los cuales fueron evaluados inicialmente según unos criterios de inclusión y exclusión, seleccionando 50 para ser usados en esta revisión. Los criterios de inclusión comprendieron estudios que abordaran específicamente los factores de riesgo, tanto genéticos como no genéticos para el desarrollo de la TVP y sus generalidades. Se incluyeron estudios de investigación originales y en menor medida artículos de revisión. Los criterios de exclusión se centraron en estudios que no estuvieran disponibles en idioma español o inglés y estudios relacionados con población pediátrica. Se seleccionaron artículos de procedencia global que incluyeran población mayor de 18 años y que se adecuaran al período de publicación entre 2018 y 2023. Se optó por utilizar las bases de datos PubMed y Elsevier debido a su amplia cobertura en medicina y su gran aceptación en la comunidad científica.

Conclusión:
Se evidenció que son múltiples los factores de riesgo que predisponen para la aparición de la TVP, de los cuales, en la mayoría ellos la intervención médica puede impactar positivamente para el desarrollo de la enfermedad, incluyendo las alteraciones genéticas y sus implicaciones.
Hydrothermal liquefaction: exploring feedstock for sustainable biofuel production
Authors: Mansuri Sahir Q. , Shekhawat V.P.S. 
Published: October 2024

A number of technological strategies utilizing various types of biomass for the production of hydrocarbons have been put forth but their energy intensive methods are a concern for improved efficiency of biofuel production. Hydrothermal liquefaction (HTL) has emerged as a promising and feasible technology towards utilization of lignocellulosic biomass. The suitability of different biomass feedstock for HTL is intricately tied to their macromolecular composition and process parameters. The comprehensive analysis of feedstock for hydrothermal liquefaction (HTL) signal towards the immense potential of various biomass feedstock, such as corn stover, Miscanthus, pine biomass, Spirulina, sugarcane bagasse, rice bran etc. in contributing significantly to renewable energy production. The study emphasizes that the composition of biomass is critical in influencing bio-oil yield during the HTL process. Biomass components like cellulose, hemicellulose, and lignin, each play distinct roles in determining the efficiency of conversion. Specifically, feedstock with higher cellulose and hemicellulose content, such as Miscanthus and sugarcane bagasse, demonstrate superior bio-oil yields. The analysis of proximate factors affecting HTL efficiency reveals that moisture content, ash content and high heating value (HHV) are pivotal in optimizing the process. In addition to composition and physical characteristics, the article underscores the significance of growth conditions and nutrient utilization in cultivating biomass feedstock. Integrating HTL with biomass cultivation can create a sustainable, closed-loop system where nutrients from the HTL process are recycled back into cultivation. Biomass offers a renewable energy alternative, however it also poses challenges related to land use and potential competition with food production. Sustainable practices, such as utilizing agricultural and forestry residues and optimizing collection as well as storage processes, can alleviate some of these concerns. By optimizing feedstock selection, process parameters, and integrating sustainable practices, HTL can play a decisive role in advancing biofuel production and contributing to a more sustainable energy future. The interplay between biomass composition, processing efficiency, environmental impacts, and economic feasibility is essential for realizing the full potential of HTL technology in the bio-economy. The current analysis sheds light on the relationship of bio-oil yield with macromolecular components including cellulose, hemicellulose, and lignin as well as process parameters like ash content, moisture content, higher heating value, fixed carbon and volatiles. Focusing on process optimization, this study embodies a closer analysis of literature aimed at defining optimum strategies for enhancement of HTL.
Atraer inversionistas extranjeros o nacionales para estimular la economía y la generación de más empleo formal en Cúcuta
Authors: Agredo-Hernández Estefanía , Delgado-Niño Adriana Lucia , Barrios Monsalve Ender José 
Published: October 2024

Esta investigación tiene como objetivo analizar o atraer los nuevos inversionistas a Colombia para así generar mayor economía al país, hemos notado que sí hay mejor economía esta reemplaza el desempleo por más empleos, lo cual genera una gran ayuda para la informalidad de Cúcuta gracias a las ZESES que es un gran apoyo para la ciudad podrán generar buenos empleos y la informalidad de esta manera bajaría y no sería la ciudad con más informalidad en la tasas referentes de país aun siendo una zona frontera La propuesta más clara de esta investigación es cambiar el ámbito de la informalidad en las personas por un estilo de vida nuevo bajo la informalidad incentivando a trabajar en una empresa con sus todas cesantías y prestaciones reglamentarias que puedan vivir de una manera más cómoda sabiendo que están trabajando de una forma más adecuada.
Tax Policy Uncertainty and Investment in Tax Planning: Firm-Level Evidence
Authors: Brown Jennifer , Guo Savannah , Zheng Michael 
Published: October 2024

ABSTRACT
Using a large sample of U.S. firms between 2003 and 2019, this paper employs a novel firm-level measure of tax policy uncertainty from conference call transcripts and finds that investment in tax planning is significantly lower when perceived tax policy uncertainty is higher. Cross-sectional analyses show that this negative relationship is mitigated by expected future profitability and managerial ability. Further analyses reveal several tax and nontax shareholder consequences of tax policy uncertainty, including lower tax planning effectiveness, higher tax risk, more cash holding, and lower firm value. Overall, our study contributes to the literature by showing how cross-sectionally heterogeneous tax policy uncertainty affects corporate tax decisions.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: D81; E65; G18; H25; M41; M42.
Sociopsychological aspects of adaptation of Foreign Students in the conditions of Educational Migration
Authors: Svetonosova A. Y. , Abakumova I. V. 
Published: October 2024

Introduction. In modern society, the issues of social adaptation of students in higher education institutions are becoming more and more relevant and significant. Entering the environment of a higher education institution is a complex and multifaceted process that requires students to adapt to new conditions. That is why the study of socio-psychological aspects of adaptation of foreign students in Russian universities is an important direction for the scientific field. In the framework of our study we considered theoretical aspects of social adaptation of international students, the problems they have to face, as well as students’ attitudes towards their studies and chosen specialty.Objective. Analyze the sociopsychological aspects of adaptation of foreign students in the conditions of educational migration.Materials and Methods. In this study, a survey method was applied: questionnaires and interviews. During the application of the stated methods, it is possible to identify the personal characteristics of educational migrants, to familiarize with the specifics of perception of difficult life situations by young people prone to experience, and to obtain information about the general satisfaction and dissatisfaction of educational migrants with educational activities and self-assessments of their performance in the course of social adaptation.Results. The study involved 136 international students aged 18–25 years. During the course of the study, data on the prevalence of various barriers in the adaptation process were obtained by the survey method. They show that the greatest significance and difficulty for foreign students were first of all the problems related to language communication, the lack of knowledge of the Russian language. Accordingly, it involved the formation of problems with studies and worries related to the realization and well-being. Insufficient preparation of students for new conditions of the educational process can lead to stress, disorientation, and low motivation.Discussion. As a result of the study, it can be concluded that sociopsychological aspects play an important role in the adaptation of educational migrants to new conditions and culture, which requires special attention and support from educational and social institutions.