bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing a safety climate tool adapted to address respiratory illnesses in Canadian hospitals
Authors: Jiang Lili , Muller Matthew , McGeer Allison , Simor Andrew , Holness D. Linn , Coleman Kristy K.L. , Katz Kevin , Loeb Mark , McNeil Shelly , Nichol Kathryn , Powis Jeff , Coleman Brenda L. 
Published: October 2024

Abstract

Background:
Studies have shown an association between workplace safety climate scores and patient outcomes. This study aimed to investigate (1) performance of the hospital safety climate scale that was adapted to assess acute respiratory illness safety climate, (2) factors associated with safety climate scores, and (3) whether the safety scores were associated with following recommended droplet and contact precautions.

Methods:
A survey of Canadian healthcare personnel participating in a cohort study of influenza during the 2010/2011–2013/2014 winter seasons. Factor analysis and structural equation modeling were used for analyses.

Results:
Of the 1359 participants eligible for inclusion, 88% were female and 52% were nurses. The adapted items loaded to the same factors as the original scale. Personnel working on higher risk wards, nurses, and younger staff rated their hospital’s safety climate lower than other staff. Following guidelines for droplet and contact precautions was positively associated with ratings of management support and absence of job hindrances.

Conclusion:
The adapted tool can be used to assess hospital safety climates regarding respiratory pathogens. Management support and the absence of job hindrances are associated with hospital staff’s propensity and ability to follow precautions against the transmission of respiratory illnesses.
Description of a new Ornithodoros (Pavlovskyella) (Ixodida: Argasidae) tick species from Pakistan
Authors: Ali Abid , Khan Mehran , Numan Muhammad , Alouffi Abdulaziz , Almutairi Mashal M. , Pienaar Ronel , de Castro Minique H. , Chitimia-Dobler Lidia , Muñoz-Leal Sebastián , Mans Ben J. 
Published: October 2024

AbstractThe genus Ornithodoros is notably diverse within the family Argasidae, comprising approximately 134 species distributed among 4 subgenera, 1 of which is the subgenus Pavlovskyella. In an earlier study, we identified distinct soft ticks as Ornithodoros (Pavlovskyella) sp., which were collected from animal shelters in Khyber Pakhtunkhwa, Pakistan. Providing additional collections from that same locality and a comprehensive analysis involving detailed morphological and mitogenome-based comparisons with closely related species, this study formally designates a novel species for these specimens. Adults and late-instar nymphs of the new species display a dorsoventral groove, small cheeks not covering the capitulum, 5 small even humps on tarsus I and a transverse postanal groove intersecting the median postanal groove perpendicularly. It also lacks a tuft of setae on the ventral surface of the hood which separates the novel species from Ornithodoros papillipes. Ventral chaetotaxy of tarsus IV indicates 4–7 setal pairs in nymphs and 5–7 pairs in adults that separate the new species from Ornithodoros tholozani sensu stricto and Ornithodoros crossi, 2 morphologically closely related species that occur in geographical proximity. Phylogenetic analyses of the full-length mitochondrial genome and the 18S and 28S ribosomal RNA genes, combined with pairwise nucleotide comparisons of cox1, cox2, atp8, atp6, cox3, nad3, nad5, nad4, nad4L, nad6, cytb, nad1, nad2, 12S rDNA, 16S rDNA, 18S rDNA and 28S rDNA further support that the new species belongs to the Pavlovskyella subgenus, clustering with O. tholozani, Ornithodoros verrucosus and Ornithodoros tartakovskyi.
Stød and stress location in Danish: A nonce word study
Authors: Høeg Annika 
Published: October 2024

Abstract
In Danish, the distribution of stød exhibits a pattern related to the position of the stressed syllable. Some phonological theories of stød, e.g. Basbøll (2005), consider stød on the antepenultimate or ultimate syllable, and non-stød on the penultimate syllable, to be the default. This article reports on a production study with nonce words, investigating the distributional pattern of stød in relation to the position of the stressed syllable in monomorphemic nonce words. Ten speakers were asked to pronounce 336 nonce words with stress on either the ultimate, penultimate, or antepenultimate syllable. The results showed that stød on ultimate stressed syllables and non-stød on penultimate stressed syllables replicates in nonce words, but stød on antepenultimate stressed syllables does not. This suggests that stød in antepenultimate stressed words is not the default, but lexical.
Mpox in UK households: estimating secondary attack rates and factors associated with transmission, May–November 2022
Authors: Packer Simon , Patrzylas Piotr , Merrick Rachel , Sawyer Clare , McAuley Andrew , Crowe William , Armstrong Gillian , Green Leonardo , Findlater Lucy , Turner Charlie , Edeghere Obaghe , Anderson Charlotte 
Published: October 2024

Abstract
We aimed to estimate the secondary attack rate of mpox among UK household contacts and determine factors associated with transmission to inform public health management of contacts, during the global outbreak in 2022. Information was collected via NHS and public health services and included age, gender, place of residence, setting, and type of contact. Aggregate information was summarized for the UK. Record level data was combined for England, Wales and Northern Ireland, and multivariable logistic regression was used to determine factors associated with transmission. The secondary attack rate among UK household mpox contacts was 4% (60/1 526). Sexual contact with the index case was associated with a 11-fold increase in adjusted odds of becoming a case in England, Wales, and Northern Ireland (95% CI 5.5–22, p < 0.001). Household contacts outside of London had increased odds compared to London residents (adjusted OR 2.9, 95%CI 1.6–5.4, p < 0.001), while female contacts had reduced odds of becoming a case (aOR: 0.41, 95% CI: 0.15–0.95). We found a low overall secondary attack rate among household mpox contacts with strong evidence of increased transmission risk associated with sexual contact. This evidence will inform the risk assessment of contacts and support prioritization of those with close intimate contact for follow up.
Risk factors for COVID-19 transmission in England: a multilevel modelling study using routine contact tracing data
Authors: Moore Hannah L. , Turner Charlie , Rawlinson Chris , Chen Cong , Verlander Neville Q. , Anderson Charlotte , Hughes Gareth J. 
Published: October 2024

Abstract
Contact tracing for COVID-19 in England operated from May 2020 to February 2022. The clinical, demographic and exposure information collected on cases and their contacts offered a unique opportunity to study secondary transmission. We aimed to quantify the relative impact of host factors and exposure settings on secondary COVID-19 transmission risk using 550,000 sampled transmission links between cases and their contacts. Links, or ‘contact episodes’, were established where a contact subsequently became a case, using an algorithm accounting for incubation period, setting, and contact date. A mixed-effects logistic regression model was used to estimate adjusted odds of transmission. Of sampled episodes, 8.7% resulted in secondary cases. Living with a case (71% episodes) was the most significant risk factor (aOR = 2.6, CI = 1.9–3.6). Other risk factors included unvaccinated status (aOR = 1.2, CI = 1.2–1.3), symptoms, and older age (66–79 years; aOR = 1.4, CI = 1.4–1.5). Whilst global COVID-19 strategies emphasized protection outside the home, including education, travel, and gathering restrictions, this study evidences the relative importance of household transmission. There is a need to reconsider the contribution of household transmission to future control strategies and the requirement for effective infection control within households.
Resting energy expenditure during spinal cord injury rehabilitation and utility of fat-free mass-based energy prediction equations: a pilot study
Authors: Nevin Amy N. , Atresh Sridhar S. , Vivanti Angela , Ward Leigh C. , Hickman Ingrid J. 
Published: October 2024

Abstract
Study design
Longitudinal observational study. Measurements were undertaken between weeks 4–6 post-spinal cord injury (SCI), repeated at week 8 and every 4 weeks thereafter until week 20 or rehabilitation discharge, whichever occurred first.

Objectives
Observe variation in measured resting energy expenditure (REE) and body composition in males undergoing SCI rehabilitation, compare REE with SCI-specific prediction equations incorporating fat-free mass (FFM), and explore the prevalence of clinical factors that may influence individual REE.

Setting
Spinal Injuries Unit, Brisbane, Queensland, Australia.

Methods
Indirect calorimetry was used to measure REE and bioimpedance spectroscopy to assess body composition. Four SCI-specific FFM-based REE and basal metabolic rate (BMR) prediction equations were compared to measured REE. A clinically significant change in REE was defined as +/− 10% difference from the week 4–6 measurement. Clinical factors that may affect REE variations were collected including infection, pressure injuries, autonomic dysreflexia, spasticity, and medications.

Results
Fifteen people participated (mean age 35 ± 13 years, 67% paraplegic). There was no statistically significant change in mean REE, weight, or body composition, and the Chun and Nightingale BMR prediction equations performed best (rc > 0.8 at all time points). One-third of participants had >10% change in REE on 11 occasions, with clinical factors not consistently associated with the observed changes.

Conclusion
During SCI rehabilitation, mean REE, weight, and body composition remain unchanged, and FFM-based BMR prediction equations may be an acceptable alternative to indirect calorimetry. Future research designs should avoid single indirect calorimetry measures as snapshot data may not represent typical REE in this population.
Household electricity consumption prediction using database combinations, ensemble and hybrid modeling techniques
Authors: Ramnath Gaikwad Sachin , Harikrishnan R. , Muyeen S. M. , Kotecha Ketan 
Published: October 2024

AbstractHousehold electricity consumption (HEC) is changing over time, depends on multiple factors, and leads to effects on the prediction accuracy of the model. The objective of this work is to propose a novel methodology for improving HEC prediction accuracy. This study uses two original datasets, namely questionnaire survey (QS) and monthly consumption (MC), which contain data from 225 consumers from Maharashtra, India. The original datasets are combined to create three additional datasets, namely QS + MC, QS equation (QsEq) + next month’s consumptions, and QsEq + MC. Furthermore, the HEC prediction accuracy is boosted by applying different approaches, like correlation methods, feature engineering techniques, data quality assessment, heterogeneous ensemble prediction (HEP), and the hybrid model. Five HEP models are created using dataset combinations and machine learning algorithms. Based on the MC dataset, the random forest provides the best prediction of RMSE (36.18 kWh), MAE (25.73 kWh), and R2 (0.76). Similarly, QsEq + MC dataset adaptive boosting provides a better prediction of RMSE (36.77 kWh), MAE (26.18 kWh), and R2 (0.76). This prediction accuracy is further increased using the proposed hybrid model to RMSE (22.02 kWh), MAE (13.04 kWh), and R2 (0.92). This research work benefits researchers, policymakers, and utility companies in obtaining accurate prediction models and understanding HEC.
A cofactor-induced repressive type of transcription factor condensation can be induced by synthetic peptides to suppress tumorigenesis
Authors: Tang Yang , Chen Fan , Fang Gemin , Zhang Hui , Zhang Yanni , Zhu Hanying , Zhang Xinru , Han Yi , Cao Zhifa , Guo Fenghua , Wang Wenjia , Ye Dan , Ju Junyi , Tan Lijie , Li Chuanchuan , Zhao Yun , Zhou Zhaocai , An Liwei , Jiao Shi 
Published: October 2024

AbstractTranscriptional factors (TFs) act as key determinants of cell death and survival by differentially modulating gene expression. Here, we identified many TFs, including TEAD4, that form condensates in stressed cells. In contrast to YAP-induced transcription-activating condensates of TEAD4, we found that co-factors such as VGLL4 and RFXANK alternatively induced repressive TEAD4 condensates to trigger cell death upon glucose starvation. Focusing on VGLL4, we demonstrated that heterotypic interactions between TEAD4 and VGLL4 favor the oligomerization and assembly of large TEAD4 condensates with a nonclassical inhibitory function, i.e., causing DNA/chromatin to be aggregated and entangled, which eventually impede gene expression. Based on these findings, we engineered a peptide derived from the TEAD4-binding motif of VGLL4 to selectively induce TEAD4 repressive condensation. This “glue” peptide displayed a strong antitumor effect in genetic and xenograft mouse models of gastric cancer via inhibition of TEAD4-related gene transcription. This new type of repressive TF phase separation exemplifies how cofactors can orchestrate opposite functions of a given TF, and offers potential new antitumor strategies via artificial induction of repressive condensation.
Patient-centered pregnancy planning in multiple sclerosis: evidence for a new era
Authors: Melo Elisa Matias Vieira de , Rodrigues Bruno Cassis Antunes , Cabral Felipe Teijeiro , Villarim Luíza Alves Monteiro Torreão , Mendes Maria Fernanda 
Published: October 2024

AbstractA few decades ago, women diagnosed with multiple sclerosis were discouraged from becoming pregnant. However, with new knowledge about the disease and treatments, this recommendation has changed, and it is pregnancy after the diagnosis of the disease is no longer contraindicated, with family planning being essential in this process. This review aims to provide a comprehensive overview of the family planning process for people with multiple sclerosis.
14 Bioorthogonal Strategies for the Uncaging and Assembly of Drugs
Authors: Adam C. , Lorente-Macías Á. , Croke S. , Unciti-Broceta A. 
Published: October 2024

AbstractThe bioorthogonal synthesis of drugs offers a unique opportunity for targeting — either molecularly, spatiotemporally or both — the delivery of active compounds directly to the disease site. Problems such as unfavorable pharmacokinetic (PK) profiles and dose-limiting side effects can be mitigated with the careful deployment of the tools of biorthogonal chemistry. In order to access medicinal applications, researchers have developed groundbreaking new chemistries for the caging and uncaging, assembly, and molecular targeting of a wide range of clinically approved drugs. This review presents notable examples of bioorthogonal drug synthesis that have emerged from the two main branches of the bioorthogonal field: organic click chemistries and transition-metal-catalyzed reactions.
Analysis and simulation of opto-electronics characterization of two-dimensional Janus monolayers for energy applications
Authors: Bin Li , Shahzad Muhammad , Sadi Muhammad Abdullah , Bitew Girmaw Teshager , Farhan Muhammad , Ali Saqib 
Published: October 2024

First-principles simulations are conducted to investigate the absorption and optoelectronic efficacy of molybdenum–sulfur–selenium, referred to here as MoSSe, and molybdenum–sulfur–oxygen, referred to here as MoSO, Janus monolayers. The materials MoSSe and MoSO demonstrate characteristics of semiconductors, as they possess bandgaps of 2.00 eV (direct) and 1.61 eV (indirect), respectively. This property renders them highly suitable for efficient light absorption. The efficiency of absorption of the device was calculated for the MoSSe and MoSO families, leading to the observation that these material families demonstrate a broad absorption range spanning from the infrared to the ultraviolet regions of the electromagnetic spectrum. This finding represents a novel discovery. Furthermore, the design as a topmost cell is particularly attractive due to its exceptional device absorption efficiency and broader bandgap. This particular family ensures that its band edges remain in alignment with the water-redox potentials. Molybdenum sulfide and molybdenum selenide exhibit promising potential as photocatalysts and in optoelectronic device applications. This is attributed to their appealing photocatalytic properties and notable efficiency in absorbing light for the purpose of water splitting.
Novel structures and collapse of solitons in nonminimally gravitating dark matter halos
Authors: Chen Jiajun , Zhang Hong-Yi 
Published: October 2024

Abstract
Ultralight dark matter simulations predict condensates with short-range correlation, known as solitons or boson stars, at the centers of dark matter halos. This paper investigates the formation and collapse of dark matter solitons influenced by nonminimal gravitational effects, characterized by gradient-dependent self-interactions of dark matter and an additional source in Poisson's equation for gravity. Our simulations suggest that the initial evolution of dark matter resembles that without nonminimal gravitational effects. However, regions with negative potential curvature may develop, and solitons will collapse when their densities reach certain critical values for both positive and negative coupling constants. With strong nonminimal gravitational effects, we verify that linear density perturbations could grow on both large and small scales, potentially enhancing structure formation.
Explaining PTA data with inflationary GWs in a PBH-dominated universe
Authors: Datta Satyabrata 
Published: October 2024

AbstractWe show that an ultralight primordial black hole (PBH) dominated phase makes blue-tilted inflationary gravitational waves (BGW) compatible with the recent detection of an nHz stochastic GW background by pulsar-timing arrays (PTAs), for high reheating temperatures. This PBH-dominated phase suppresses the BGW spectrum via entropy dilution, making it consistent with strong constraints from LIGO O3 and BBN. A future observation of such GW spectral features at mid or high frequencies can strongly constrain the possible mass range of PBHs. Since PBHs can exhibit various other unique signatures, they can be distinguished from spectra generated by other types of matter domination or exotic physics. Therefore, while important for studying GWs in the nHz range, the recent PTA result also sets the stage for testing and constraining various well-studied mechanisms following a PBH domination, using low-frequency measurements and correlated observations of unique high-frequency GW spectral features.
Distribution of quantum gravity induced entanglement in many-body systems
Authors: Ghosal Pratik , Ghosal Arkaprabha , Bandyopadhyay Somshubhro 
Published: October 2024

Abstract
Recently, it was shown that if two distant test masses, each in a spatially superposed quantum state, become entangled due to their mutual gravitational interaction, then this entanglement could serve as evidence of the quantum nature of gravity. We extend this treatment to a many-body system in a general setup and study the entanglement properties of the time-evolved state. We exactly compute the time-dependent I-concurrence for every bipartition and obtain the necessary and sufficient condition for the creation of genuine many-body entanglement. We further show that this entanglement is of generalised GHZ type when certain conditions are met. We also evaluate the amount of multipartite entanglement in the system using a set of generalised Meyer-Wallach measures.
Improving microstructure and mechanical properties of WAAMed Al with UV introduced via a torch clamp
Authors: Jiao Hao , Chen Maoai , Zhang Jianhua , Jia Chuanbao 
Published: October 2024

Abstract
Ultrasonic assisting is considered to be a promising technology for industrial applications due to its ability to improve the quality of the WAAMed component. A specially designed ultrasonically vibrating torch clamp (UV torch clamp) was used to introduce the UV in the WAAM process of Al alloy for the first time. UV effect on the forming accuracy, microstructure and mechanical properties of WAAMed Al thin-walled component were investigated. The results show that the UV applied via the UV torch clamp changed the metal transfer mode, and increased the transfer frequency by at least 7.42% compared with that without UV at various Wire Feed Speed (WFSs). The applied UV caused slight increases in the surface roughness of the deposited thin-wall components at low WFSs and obvious decreases at high WFSs, the most significant reduction occurred with WFS = 8 m min−1, the surface roughness decreased from 1.04 to 0.44. The grain size and the pore size and density in the deposit were significantly reduced by the UV, and the higher the WFS, the greater the grain refinement effectiveness and the pore suppression effectiveness. The UTS and fracture elongation of the specimen with UV application increased by at least 4.6% (from 277 Mpa to 290 Mpa for longitudinal specimen with WFS = 5 m min−1, ) and 3.3% (from 21.42% to 22.12% for vertical specimen with WFS = 8 m min−1) respectively at various WFSs compared to the specimen without UV application.
Determinants of crop insurance participation of farming households in Mekong River Delta, Vietnam in climate change context
Authors: Lan Do Huong , Truong Dinh Duc , Lan Bui Thi Hoang , Hang Nguyen Dieu , Huy Huan Le 
Published: October 2024

Abstract
Agricultural insurance has been implemented in many countries around the world to reduce risks for farming households. In Vietnam, agriculture is the most important industry but is heavily affected by natural disasters and climate change. This study aimed at assessing farmers’ awareness of climate change and analyzing factors affecting agricultural insurance participation of farmers in the Mekong Delta, Vietnam. The research applied utility theory to build empirical model. We collected primary data from a survey of 400 farming households in Tra Vinh province. Households were selected stratifiedly in 4 coastal districts and then drawn randomly from household lists of communes. The research results showed that the majority of people were aware of climate change trends locally and its impacts on agricultural production. Logit regression model indicated that there were 8 main factors affecting household’s participation in crop insurance including age, gender, farming experience, education level, access to insurance information, civic organization membership, fund borrowing and household size, of which access to insurance information had strongest impact. The study proposed some specific management implications including (i) raising farmer awareness about agricultural insurance through official information channels such as television, radio, as well as informal information through social networks; (ii) strengthen the role of local civic organizations, especially extension services in disseminating information and supporting insurance purchasing activities for farmer households and; (iii) support farmers in part with insurance fees or allow access to small credit from State programs to enhance the participation of agricultural insurance.