bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphologic and hemodynamic analysis of intracranial mirror aneurysms
Authors: Spitz L. , Schmidt J. , Korte J. , Berg P. , Behme D. , Neyazi B. , Preim B. , Saalfeld S. 
Published: September 2024

Abstract
Intracranial mirror aneurysms are pathologic dilatations of cerebral arteries that occur at identical locations in both hemispheres. They do not always have identical sizes, shapes, or rupture states, despite identical patient-specific risk factors. As a subgroup of multiple aneurysms and thus small amounts of data, clinical research about their causes and development has not been conclusive. Using eight patients with 16 mirror aneurysms with different rupture states, we investigated differences between the hemispheres. We virtually performed stitching: detaching the aneurysm domes to place them on the opposite parent vessel to assess the influence of aneurysm morphology and upstream parent vessel shape on hemodynamics. In the unaltered datasets, we found that blood flow within aneurysms in the left hemisphere has higher wall shear stress and velocity. After stitching, we found that both upstream parent vessel as well as aneurysm morphology influence hemodynamics. Morphologic parameters like size, undulation index, and aneurysm angle had a higher influence. In a short rupture risk analysis we found a correlation between rupture and aspect ratio and non-sphericity index. Overall, we found possible indicators for mirror aneurysm analysis that illustrated the importance of morphological analysis, though more datasets are necessary for conclusive statements about special treatment for mirror aneurysms.
Hyper-redundant endoscopic manipulator position compensation under external load
Authors: Giacoppo Giuliano A. , Schulze Eric , Pott Peter P. 
Published: September 2024

Abstract
This paper focuses on determining the cable tension required for a cable-driven endoscopic manipulator to reach a given position under an external load at the end effector. The aim is to restore the initial position of the end effector without an external force. A simulation was performed using MATLAB, where mathematical models and algorithms were used to calculate the required tension. The mathematical model, based on Optimized Motion Estimation Analysis, considers the joint stiffness and the influence of gravity, in addition to the cable tensions and external load. The algorithm minimizes the sum of moments to achieve a stable position. An optical tracking system was used to validate the simulation results against experimental data. The manipulator successfully compensated for an external load of 1.96N and returned to its initial position with adjusted cable tensions. The results showed that the manipulator was deformed by an external load, highlighting the need to adjust the cable tension for position compensation. The discrepancies between the experimental and simulation results were due to factors such as marker size, as well as joint imperfections due to manufacturing and friction effects. Nevertheless, the proposed method proved to be effective in compensating for external loads and restoring the manipulator to the desired position.
Interactive Surgical Liver Phantom for Cholecystectomy Training
Authors: Schüßler Alexander , Younis Rayan , Paik Jamie , Wagner Martin , Mathis-Ullrich Franziska , Kunz Christian 
Published: September 2024

Abstract
Training and prototype development in robotassisted surgery requires appropriate and safe environments for the execution of surgical procedures. Current dry lab laparoscopy phantoms often lack the ability to mimic complex, interactive surgical tasks. This work presents an interactive surgical phantom for the cholecystectomy. The phantom enables the removal of the gallbladder during cholecystectomy by allowing manipulations and cutting interactions with the synthetic tissue. The force-displacement behavior of the gallbladder is modelled based on retraction demonstrations. The force model is compared to the force model of ex-vivo porcine gallbladders and evaluated on its ability to estimate retraction forces.
Symmetric single-input eccentric tube robot (ETR) for manual use
Authors: Mayer Juliane , Dumancic Marcel , Pott Peter P. 
Published: September 2024

Abstract
Concentric tube robots (CTR) have gained popularity in robotic research due to their potential for smaller instrument sizes, enhanced dexterity and reduced trauma. However, CTR control can be complex, with tip direction and curvature being kinematically coupled. To address this, a symmetric eccentric tube robot (ETR) is presented, where three identical pre-curved wires are arranged in parallel and constrained by an outer sheath. Instrument curvature is controlled by a single input angle. This study aims to demonstrate the suitability as manually actuated instrument. A model for curvature as a function of input angle is presented, and a prototype ETR with an outer diameter of 1 mm is assembled and evaluated. The results show that the ETR follows the expected shape, the curvature decreasing with the separation angle in an almost linear way that may be perceived as intuitive and predictable by the human user. However, some unsteady behavior (snapping) is observed, which may be addressed by preventing torsion of the wires through mechanical means. The simplified model neglecting the sheath stiffness provides precise enough predictions for the working space of a manual ETR. The findings suggest that manual ETRs have potential applications in superficial interventions, such as injections, arthroscopy, or ophthalmic surgery, where their curved section can be beneficial in comparison to current straight needles. Further research could explore interlocking mechanical designs to prevent torsion or modular setups for enhanced functionality.
Metaphorical constructs and semiotic expressions in the BBC Yoruba Internet memes of English Premier League match results
Authors: Osisanwo Ayo , Alugbin Matthew 
Published: September 2024

Abstract
This paper explores the deployment of metaphors in the BBC Yoruba-medium football results of the English Premier League, examining how cultural metaphorical choices shape meaning in online sport discourse. Through a discourse analysis of Yoruba-medium football results, the study reveals how metaphors drawn from Yoruba cultural milieu and everyday life are used to create vivid descriptions of game events, players, and teams. The study relies on Lakoff’s conceptual metaphor theory, complemented by Kress and van Leeuwen’s social semiotic approach to multimodality. Findings reveal that metaphors describe game events, teams, and players, thus, framing the contest in unique and evocative manners, drawing on cultural and shared knowledge to shape the understanding of the game in an adversarial sense. This study, therefore, argues that metaphors are deployed to convey deeper cultural meanings and values, and add creativity to match results. The findings point to the role of language and culture in shaping the experiences of football fandom in sports and media.
Crystal structure and tautomeric state of Pigment Red 48:2 from X-ray powder diffraction and solid-state NMR
Authors: Bravetti Federica , Hühn Robert , Bordignon Simone , Reibeling Sylvia , Schmidt Martin U. 
Published: September 2024

Abstract
Pigment Red 48:2 is an industrially important hydrazone pigment, used for the colouration of plastics and printing inks. The crystal structure of the commercial phase was solved and refined from X-ray powder diffraction data. The phase (P.R.48:2, α-phase) was found to be a monohydrate with a chemical composition of Ca[C18H11ClN2O6S]·H2O. Its tautomeric state was investigated by multinuclear solid-state NMR. The 15N CPMAS unambiguously revealed the compound to adopt the hydrazone tautomeric form in the solid state. In an unrestrained Rietveld refinement, the crystal structure did not significantly change. The crystal structure was confirmed by dispersion-corrected DFT optimisation, which also included the calculation of solid-state NMR chemical shifts. Heating the monohydrate to about 200 °C results in an anhydrate (P.R.48:2, β-phase), which has not been described before. Its crystal structure was determined by X-ray powder diffraction, and confirmed by DFT-D, too. Solid-state NMR spectra confirmed that the crystal structure of P.R.48:2 remains mostly unchanged upon dehydration and that also the hydrazone tautomeric form is maintained. Both crystal structures are similar and present a double-layer structure. The non-polar layer contains the phenyl and naphthalene moieties, whereas the polar/ionic layer comprehends the calcium ions, carboxylate, sulfonate, carbonyl groups and water molecules. The calcium ions have a coordination number of 8 and 7 in the monohydrate and anhydrate phases, respectively. For the corresponding Mn salt (Pigment Red 48:4), at least two phases were found, but the quality of the powder patterns did not allow determining their crystal structures.
Cognitive and Social–Emotional Development in Girls With Fragile X Syndrome
Authors: Bartholomay Kristi L. , Lightbody Amy A. , Ma Qianheng , Jo Booil , Jordan Tracy L. , Reiss Allan L. 
Published: September 2024

OBJECTIVES
To evaluate the developmental trajectory of key cognitive, social, and emotional features in girls with fragile X syndrome (FXS).

METHODS
This longitudinal, parallel cohort study collected data between January 2018 and December 2022. Participants were evaluated 3 times with ∼12–18 months between visits. Participants included 65 girls with FXS, 6 to 16 years, and 52 age- and developmentally-matched girls without FXS. Participants’ scores from direct assessment and caregiver report evaluated 3 cognitive domains (verbal abilities, nonverbal abilities, executive function) and 4 social–emotional domains (depression, general anxiety, social behavior, and social anxiety).

RESULTS
Participants included 117 girls (mean [M] [SD] age at study entry: FXS M = 10.59 [3.00]; comparison M = 10.45 [2.40])). Omnibus tests showed 4 domains with significant group differences: Verbal (P &lt; .0001, eg, Differential Abilities Scale-II(DAS-II), Picture Vocabulary (−6.25 [1.87])), nonverbal (P &lt; .0001, eg, Kaufman Test of Educational Achievement, Third Edition, Brief Form, Math (−8.56 [2.90])), executive function (P &lt; .0001, eg, NIH Toolbox List Sorting (−6.26 [1.48])), and social anxiety (P &lt; .03, eg, Anxiety, Depression, and Mood Scale (ADAMS) Social Avoidance (1.50 [0.65])). Three domains had significant group by age interaction: Verbal (P &lt; .04, eg, DAS-II, Word Definitions (−1.33 [0.55])), social behavior (P &lt; .01, eg, Social Responsiveness Scale-2 Social Communication (1.57 [0.51])), and social anxiety (P &lt; .01, eg, ADAMS Social Avoidance (0.46 [0.19])).

CONCLUSIONS
These findings support the development of early, disorder specific interventions for girls with FXS targeting verbal and nonverbal skills, executive function, social behavior, and social anxiety.
Abnormal uterine bleeding and hysterectomy: Insights from histopathological analysis of hysterectomy specimens from a tertiary care hospital
Authors: Gul Gazala , Manzoor Rukaya , Lone Iyman Rasool 
Published: September 2024

The surgical procedure of hysterectomy, which involves the removal of the uterus, is widely performed in the field of gynecology globally. However, the frequency of hysterectomies varies across countries and regions. The study aimed to determine the most frequent cause of abnormal uterine bleeding and the age group that undergoes hysterectomies most frequently by examining the histopathological results of hysterectomy specimens. A cross-sectional study was conducted at a tertiary care hospital in India, including 218 hysterectomy specimens received over a three-year period. The specimens were processed and examined histopathologically, and data on age, indication for hysterectomy, type of hysterectomy, and presence of co-existing gynecological pathology were collected and analyzed using SPSS software. The study found that the highest frequency of hysterectomy was observed in the age group of 40-49 years, accounting for 39.9% of all cases. The most common type of hysterectomy performed was Subtotal Hysterectomy / Supracervical Hysterectomy, which accounted for 34.4% of all cases. The most frequent cause of abnormal uterine bleeding was leiomyoma, accounting for 40.4% of all cases, followed by adenomyosis, which accounted for 22.5% of all cases. The study identifies abnormal uterine bleeding (AUB), predominantly due to leiomyoma, as the leading cause of hysterectomy among women aged 40-49 years. The findings emphasize the critical role of histopathological examination in all hysterectomy specimens to detect malignancies, regardless of preoperative assessments.
A study of histomorphological features of fallopian tube and immunohistochemical stains for p53 & ki67 of the fimbrial end of fallopian tube
Authors: Nabina Leishangthem , Mutum Reeta , Laishram Rajesh Singh , Persy Haobijam , Rainy Rajkumari , Hussain Shaik Mahammad Abzal 
Published: September 2024

: Fallopian tube is the origin of ovarian cancer especially high grade serous carcinoma. Precursor lesion of ovarian cancers in the fallopian tube now recognized includes p53 signature, secretory cell outgrowth (SCOUT), tubal intraepithelial lesion in transition (TILT) and serous tubal intraepithelial lesion (STIC) through histomorphological features and by using immunohistochemical staining for p53 and ki67. This study emphasizes in detection of precursor lesion in fallopian tube in all resected fallopian tube submitted in the department during the study period. Ability to detect precursor lesion would have profound impact on preventive strategies of ovarian cancer and modalities of management of the disease in the initial stages that ultimately help in reducing the disease burden and increasing overall survival rate. : To determine the histomorphologiscl features of fallopian tube and to assess the evidence of precursor lesions in fallopian tube epithelium using immunohistochemistry stain p53 and ki67.: The study was carried out in the department of pathology in collaboration with the department of obstretics and gynecology, regional institute of medical sciences. Study was conducted for two years from September 2018 to August 2020. All the fallopian tubes specimen received during the study period were included in the study except those specimen with damaged, autolyesd, of post radiation therapy and post chemotherapy patients. A total of 120 specimen were collected. A total of 120 samples were included in the study. Mean age of the participants was 47 years with a minimum age of 24 years and maximum age of 72 years. 56. 7 % of the participants were in post menopausal age group. Out of the 120 cases only 12 cases (10 %) showed p53 signature and one case (0.8%) showed presence of STIC.: Only one case of STIC was detected in the fallopian tube where the ovary had High grade serous carcinoma. Few cases showed for p53 signature evident by using IHC p53 and ki67 which is more frequent in corresponding ovarian pathology than uterine pathology.
Association of platelet parameters with chronic complications in type 2 diabetes mellitus
Authors: Persy Haobijam , Konjengbam Ratan , Ranabir Salam , Sorokhaibam Babina 
Published: September 2024

To determine the association of platelet parameters with chronic complications in patients with type 2 diabetes mellitus.Platelets play an important role in the integrity of normal homeostasis. Altered platelet morphology and platelet hyperactivity is associated with an increased prothrombotic state. In diabetes mellitus, there is increased platelet activity which eventually play a role in the development of vascular complications which are responsible for its morbidity and mortality. A hospital based prospective cohort study was performed to study the level of platelet parameters in patients with type 2 diabetes mellitus. Platelet parameters such as platelet count, MPV (Mean Platelet Volume), PDW (Platelet Distribution Width), PCT (plateletcrit) and P-LCR (Platelet-Large Cell Ratio) were assessed using Mind ray BC-5150 Auto Haematology Analyser. The data were entered into SPSS (IBM) version 21 and descriptive statistical methods like mean, standard deviation, percentages, etc. were applied. T-test was applied to find out the association of platelet parameters in patients with type 2 diabetes mellitus at baseline and after 6 months of follow-up. The age of the study population ranged from (30-60) years. From the total of 110 participants that were followed - up, 98(89.1%) presented with micro vascular complications. On the other hand, 32(29.1%) had at least one macro vascular complication. Platelet parameters – MPV, PDW, PCT and P-LCR were found to be significantly higher in type 2 DM with micro vascular as well as macro vascular complications as compared to those without complications. Higher values of MPV, PDW, PCT and P-LCR indicates that platelet parameters can be used as better prognostic markers for early detection of diabetic complications and therefore can be used as a simple and cost-effective tool to monitor and predict the risk of micro vascular and macro vascular complications in diabetes.
Plasma cell granuloma middle ear: A rare lesion at a rare site
Authors: Somani Kavita , Singh Pretty , Poduval Sujatha 
Published: September 2024

Plasma cell granuloma (PCG) is a rare non-neoplastic lesion, characterised by proliferation of immunoreactive polyclonal plasma cells present in a fibrous background. We present a case of 30 year male who presented with left sided otalgia, tinnitus and otorrhea along with mild conductive hearing loss. On CT scan a diagnosis of CSOM with granulation tissue was made however on histological examination, on microscopy with immunohistochemistry (IHC), it was reported as plasma cell granuloma of the middle ear. Middle ear plasma cell granuloma is a rare entity only few cases are reported in literature so far. Here, we will discuss clinical presentation, histological diagnosis with IHC and management of this rare entity at an unusual location along with review of literature.
The Analyze of Translation Techniques in Despicable Me 3 Movie
Authors: Warda Ummu , Ashari Erwin , Sinaga Juwita Boneka , Adam  
Published: September 2024

Translation is frequently employed to facilitate concept expression in the target language, accelerate language acquisition, and give us more confidence when comprehending words and expressions from other languages. Translation is not merely about converting words from one language to another; it is a comprehensive process that facilitates the expression of concepts in the target language, accelerates language learning, and boosts confidence in understanding foreign words and expressions.For this study, the researcher used a descriptive qualitative research approach. In this research the researcher will translate a movie with the title is ‘Despicable me 3’ to analyze the 18 translation techniques used in the movie. the researcher analyze there are only 14 translation techniques that used in ‘Despicable me 3’ movie.
Introdução didática ao estudo da agressão pela Análise do Comportamento
Authors: Terhoch Gabriel Bueno , Soares Pedro Felipe dos Reis 
Published: September 2024

Este artigo é uma introdução didática ao estudo da agressão (comportamento agressivo) em uma perspectiva analítico-comportamental. Agressão pode ser definida como um comportamento que expõe outro(s) organismo(s) a estimulação aversiva ou que cria condições para que isso ocorra. Na condição de comportamento, a agressão está relacionada a eventos ambientais antecedentes e consequentes, e este trabalho tem como objetivo expor algumas das relações de controle já identificadas pela literatura analítico-comportamental. Primeiramente, são apontadas algumas das relações de controle do comportamento agressivo, junto a resultados experimentais que ilustram com cada relação identificada. Em seguida, o modelo experimental de agressão induzida por estimulação aversiva é brevemente apresentado e discutido. Por fim, são debatidas as implicações desse conhecimento para a prática aplicada do analista do comportamento. Destaca-se que uma perspectiva comportamental da agressão rompe com a lógica internalista que atribui apenas ao indivíduo a causa desse comportamento, permitindo maior grau de previsão e controle do comportamento agressivo a partir da ênfase à interação com variáveis ambientais. Palavras-chave: agressão, comportamento agressivo, artigo didático.
Transitioning from Full-time Employment to Entrepreneurship: How Networking Affect Entrepreneurial Survival and Success
Authors: Kumar Satish 
Published: September 2024

<p>This career shift from a salaried job to entrepreneurship is a significant change, having a number of associated challenges and opportunities. This paper examines the role of networking in enabling an entrepreneur to negotiate the challenges and succeed in his transition process. The influence of these networking activities on an individual's ability to navigate the intricate aspects involved in entrepreneurship, in enhancing the chances of survival and success in competitive business environments, is shown through analysis of already existing research and empirical evidence.</p><p>In this paper, the theoretical bases of networking in entrepreneurship are analyzed as a way to explain its importance for access to crucial resources, information, and opportunities while carrying out entrepreneurial activities. Coupling the findings of previous studies, this paper will show how and why networking can help realize the transition from full-time employment to entrepreneurship and provide expansion and durability for nascent ventures. This work will further relate research on the different types of networks, such as social networks, professional societies, mentorship programs, entrepreneurial communities, and their inferences on entrepreneurial outcomes. The research was able to delve deeper into the details of networking strategies and the implications it had on entrepreneurial survival and success in pointing out suggestions to those intending to start a business while maintaining a full-time job. </p>This paper makes a strong contribution to the entrepreneurship literature in respect of demonstrating the contribution of networking within the transition process and making the processes more likely to result in successful new businesses. Results show clearly the need for strategic networking activities by those moving from ordinary employment into entrepreneurship; this is not a passive activity, so there is an obvious requirement for the networking of active processes with different networks in order to connect with resources and opportunities that would support sustainable enterprise growth.