bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety of Quadrivalent Meningococcal Conjugate Vaccine in 11- to 21-Year-Olds
Authors: Tseng Hung-Fu , Sy Lina S. , Ackerson Bradley K. , Hechter Rulin C. , Tartof Sara Y. , Haag Mendel , Slezak Jeffrey M. , Luo Yi , Fischetti Christine A. , Takhar Harp S. , Miao Yan , Cunnington Marianne , Solano Zendi , Jacobsen Steven J. 
Published: December 2016

BACKGROUND:
Meningococcal conjugate vaccination is recommended in the United States. This study evaluates the safety of quadrivalent meningococcal conjugate vaccine in a cohort aged 11 to 21 years.

METHODS:
This cohort study with self-controlled case-series analysis was conducted at Kaiser Permanente Southern California. Individuals receiving MenACWY-CRM, a quadrivalent meningococcal conjugate vaccine, during September 30, 2011 to June 30, 2013, were included. Twenty-six prespecified events of interest (EOIs), including neurologic, rheumatologic, hematologic, endocrine, renal, pediatric, and pediatric infectious disease EOIs, were identified through electronic health records 1 year after vaccination. Of these, 16 were reviewed by case review committees. Specific risk and comparison windows after vaccination were predefined for each EOI. The relative incidence (RI) and 95% confidence intervals (CIs) were estimated through conditional Poisson regression models, adjusted for seasonality.

RESULTS:
This study included 48 899 vaccinated individuals. No cases were observed in the risk window for 14 of 26 EOIs. The RI for Bell’s palsy, a case review committee-reviewed EOI, was statistically significant (adjusted RI: 2.9, 95% CI: 1.1–7.5). Stratified analyses demonstrated an increased risk for Bell’s palsy in subjects receiving concomitant vaccines (RI = 5.0, 95% CI = 1.4–17.8), and no increased risk for those without concomitant vaccine (RI = 1.1, 95% CI = 0.2–5.5).

CONCLUSIONS:
We observed a temporal association between occurrence of Bell’s palsy and receipt of MenACWY-CRM concomitantly with other vaccines. The association needs further investigation as it could be due to chance, concomitant vaccination, or underlying medical history predisposing to Bell’s palsy.
Surface roughness influences Candida albicans biofilm formation on denture materials
Authors: Da Silva Wander José , Gonçalves Letícia Machado , Viu Flávia Carvalho , Leal Cristiane Maria Brasil , Barbosa Célia Marisa Rizatti , Del Bel Cury Altair Antoninha 
Published: December 2016

Objective: This study aimed to evaluate the influences of surface roughness (SR) of denture base and liner materials on Candida albicans biofilm formation.Methods: Discs were fabricated using poly (methyl methacrylate) acrylic resin and poly(ethyl methacrylate) denture liner, according to manufacturers’ instructions. Both acrylic resin and relined discs were finished or finished + polished and the SR was measured. Discs were saliva-coated, and C. albicans biofilms were developed on such surfaces for 48 hours. Biofilms were evaluated for cell counts, metabolic activity, and structural characteristics. Data were analyzed by one-way ANOVA and Tukey tests using a significance level of 5%.Results: Finished acrylic resin and denture liner discs had higher SR compared to finished + polished discs (P<0.001). Finished + polished acrylic resin discs contained fewer cells compared to only finished discs (P<0.001). No metabolic activity differences were seen between biofilms formed on both groups (P>0.05). Bulky, thick and less rough biofilms were formed on only finished denture materials (P<0.05). Confocal images reveal increased presence of black spaces for biofilms developed on finished + polished discs. Conclusion: Reduced SR resulted in decreased C. albicans biofilm accumulation on both denture materials.
Comparative analysis of microbial reduction using photodynamic therapy in bovine teeth infected with Enterococcus faecalis – an in vitro study
Authors: Zechin Janaina Guzzo , Steier Liviu , Rossi-Fedele Giampiero , Gründling Grasiela Longhi , Sá Daniela , Guwzinski Amanda , Trindade Alessandra Cesar , Souza Matheus Albino , Oliveira Silvia Dias de , Figueiredo Jose Antonio Poli de 
Published: December 2016

Objective: To evaluate the use of optic fiber and different pre-irradiation times (PIT) in phototherapy with LED for the root canal disinfection of bovine teeth infected in vitro with Enterococcus faecalis.Methodology: The teeth were incubated for 60 days and divided into six groups according to disinfection protocol: Group 1 – distilled water; Group 2 – 1 minute PIT and no optic fiber; Group 3 – 1 minute PIT and optic fiber; Group 4 – 5 minute PIT and no optic fiber; Group 5 – 5 minute PIT and optic fiber; Group 6 – 2% sodium hypochlorite. Microbiological test (CFUs counting) and scanning electron microscopy (SEM) were performed to evaluate the effectiveness of proposed treatments.Results: SEM analysis of canal wall, in the three thirds, revealed group 6 had the best results, whereas microbiological results revealed that group 6 had the best results. No differences in disinfection of root canals were found when optic fiber was used for photodynamic therapy. Conclusion: Photodynamic therapy should not be used alone in the disinfection of root canals, but it may be valuable as a complement for disinfection performed using different cleaning methods.
Orthodontic shear bond strength to porcelain surface in wet conditions
Authors: Guimarães Magáli Beck , Cocco Bárbara , Bueno Rodrigo Salbego , Blaya Micéli Beck Guimarães , Jacques Letícia Borges , Hirakata Luciana Mayumi 
Published: December 2016

Objective: To evaluate the shear bond strength of orthodontic accessories bonded to a porcelain surface after storage in water.Methods: One-hundredand-twenty feldspathic porcelain discs were divided into 4 groups, according to the surface treatment: Group 1 – 37% phosphoric acid etching; Group 2 – 10% fluorhydric acid; Group 3 – 37% phosphoric acid and silane application; Group 4 – 10% fluorhydric acid and silane application. After the accessories were bonded, the sample was divided into two subgroups, according to the time interval of storage in distilled water: Control – 24 hours; and Test – 150 days. Shear bond strength was determined using a universal test machine, and failure type was verified by scanning electron microscopy.Results: In the test groups there was reduction in shear bond strength, particularly when silane was used. Test Groups 2 and 4 presented shear bond strength values within those proposed as adequate for orthodontic bonding. Groups 1 and 3 presented adhesive failures between porcelain and resin, whereas in Groups 2 and 4 cohesive failures in porcelain were recorded.Conclusion: Storage in water for 150 days decreased the bond strength at silanized interfaces. Fluorhydric acid etching generates adequate bond strength in wet conditions, however, increases the fracture rate in porcelain.
Jelszómenedzser szoftver alkalmazása az egészségügyben
Authors: Ködmön József 
Published: December 2016

Abstract: When using multiple IT systems, handling of passwords in a secure manner means a potential source of problem. The most frequent issues are choosing the appropriate length and complexity, and then remembering the strong passwords. Password manager software provides a good solution for this problem, while greatly increasing the security of sensitive medical data. This article introduces a password manager software and provides basic information of the application. It also discusses how to select a really secure password manager software and suggests a practical application to efficient, safe and comfortable use for health care. Orv. Hetil., 2016, 157(52), 2066–2073.
Marketing research in positioning and launching of yoghurt with a balanced chemical composition
Authors: Mardar M. , Tkachenko N. , Lilishentseva A. , Burlaka H. 
Published: December 2016

Annotation. This article presents the analysis of marketing environment of the enterprises that produce yogurt products in Ukraine. In order to carry out a deeper analysis of the marketing environment of the new yoghurt drinks with a balanced composition of the major nutrients in food and increased probiotic properties, PEST and SWOT-analyses were conducted, they identified environmental factors that have favorable and adverse effects as well as internal strengths and weaknesses of the new product. Based on the results of marketing research of consumer preferences, the core audience of new yoghurt drink with a balanced chemical composition and the elevated concentration of Bifidobacteria were defined. The received results led to justification of the expediency of elaboration of new yoghurt drinks with probiotic properties and balanced composition of basic food nutrients as well as to formulation of a strategy of new product promotion on the consumer market of Ukraine.
Використання пшона у виробництві хліба оздоровчого призначення
Authors: Дубініна А.А. , Ленерт С.О. , Попова Т.М. 
Published: December 2016

У статті обґрунтовано доцільність використання крупи пшоно у виробництві хлібобулочних виробів. Наведено результати розробки рецептурного складу нового виду хліба із пшеничного борошна з додаванням пшона, попередньо відвареного до напівготовності. Із метою створення виробу оздоровчого призначення запропоновано використання сухих заквасок замість термофільних дріжджів. Для поліпшення структурно-механічних властивостей тіста та покращення якості пшоняного хліба запропоновано введення в рецептуру ферментних препаратів з геміцелюлазною активністю, зокрема препарату Пентопан 500 BG виробництва фірми «Novozymes A/S». Визначено органолептичні та фізико-хімічні показники якості контрольного зразка хліба (без додавання пшона) та дослідних зразків з різною кількістю внесеного пшона. Встановлено доцільність заміни борошна пшеничного на пшоно у кількості 20 – 30 %. Показано, що хліб з таким вмістом пшона характеризується підвищеною харчовою цінністю і одночасно має достатньо високі показники якості, які повністю відповідають встановленим вимогам.
Моніторинг безпечності та якості природної мінеральної води свердловини № 14/7832 м. Одеса
Authors: Нікіпелова О.М. 
Published: December 2016

Проблема формування хімічного складу та біоценозів підземних вод досі є однією з найбільш складних проблем теоретичної гідрогеології. Найбільший інтерес представляють такі процеси, як зміни фізико-хімічного складу та мікробіологічного стану підземних вод. Моніторинг підземних вод та санітарно-мікробіологічні дослідження розглянуто на прикладі природної мінеральної води свердловини № 14/7832 м. Одеса з часом. Дослідження проводилися ДУ «УкрНДІ МРтаК МОЗ України» з 1999 по 2010 рр. На основі отриманих даних побудовано графіки, на які накладено апроксимаційні лінії. Їх використано для визначення можливої зміни макрокомпонентів та мінералізації. Взагалі, загальна тенденція залишається незмінною. Санітарно-мікробіологічний стан мінеральної води свердловини був задовільним.
Acessibilidade Arquitetônica e Desenho Universal no Mundo e Brasil
Authors: Feitosa Lucas de Souza Ramalhaes , Righi Roberto 
Published: December 2016

Este artigo objetiva mostrar o surgimento e desenvolvimento dos conceitos modernos de acessibilidade, desenho universal, acessibilidade no Brasil e mundo, e envolvendo a preocupação com espaços acessíveis e universais para atender as pessoas, possuindo ou não algum tipo de deficiência e as questões para inclusão social. Houve um agravamento na demanda por acessibilidade resultante de um aumento absoluto e relativo do número de pessoas com deficiência no Brasil e mundo, que é abordado neste trabalho. PALAVRAS-CHAVE: Acessibilidade, Pessoa com Deficiência; Desenho Universal; Inclusão Social, Ergonomia. Architectural Accessibility and Universal Design in the World and Brazil ABSTRACTThis article aims to show the emergence and development of accessibility concepts, universal design, accessibility in Brazil, and involving the concern spaces accessible and universal to meet people, having or not some kind of disability and issues for social inclusion. There was an increase in demand for accessibility resulting from an absolute and relative increase in the number of people with disabilities in Brazil and the world, which is covered in this work KEYWORDS: Accessibility; Person with Disabilities; Universal Design; Social Inclusion; Ergonomics. Accesibilidad Arquitectónica y el Diseño Universal em el Mundo y BrasilRESUMEN Este artículo tiene como objetivo mostrar la aparición y el desarrollo de los conceptos de accesibilidad modernas, el diseño universal, accesibilidad en Brasil y en el mundo, y la participación de los espacios preocupación accesible y universal para conocer gente, tener o no algún tipo de discapacidad y las cuestiones de inclusión social. Hubo un aumento de la demanda de accesibilidad como resultado de un aumento absoluto y relativo en el número de personas con discapacidades en Brasil y en el mundo, que se cubre en este trabajo. PALAVRAS-CHAVE: Accesibilidad, Persona con Discapacidad, Diseño Universal, La Inclusión Social, Ergonomía.
Complication profile of scrub typhus and its association with total leucocyte count
Authors: Gupta Palak , Gurjar Umesh , Sharma B. S. , Gupta M. L. 
Published: December 2016

Background: Recent reports from several parts of India indicate that there is a resurgence of scrub typhus. There have been a few studies analysing the association of various complications of scrub typhus with leukocyte count. The objective of this study was to study the association of various complications of scrub typhus with leukocyte count in children.Methods: A prospective study done at SPMCHI, SMS Medical College, Jaipur from August 2014 to November 2014. 75 Scrub typhus positive children were included in the study group. A detailed history of signs, symptoms, complications, demographic background was taken and relevant laboratory investigations done. The association between the complications of scrub and the total leukocyte count was studied, statistical analysis was done using Chi Square test.Results: Meningoencephalitis was most commonly seen complication in 14.7% followed by ARDS (9.3%), hepatitis (8%), AKI (6.7%), shock (6.7%) and myocarditis (1.3%). Meningoencephalitis and acute renal failure were more frequent among Scrub Typhus cases with leucopenia (p = 0.006, P = 0.011 respectively). It was observed that hepatitis was more frequent with leukocytosis, but was not statistically significant.Conclusions: Our study revealed that leukopenia has a significant association with meningoencephalitis and acute kidney injury.
Parent stress in neonatal intensive care unit: an unattended aspect in medical care
Authors: Agrawal Ruma , Gaur Ajay 
Published: December 2016

Background: The birth of an infant that needs care in a neonatal intensive care unit (NICU) can be stressful for the parents. The parent-infant bonding process that occurs during the newborn period establishes the foundation for a lifelong relationship. This typical process does not occur when the infant spends the first several weeks or months in the NICU. Quantifying stress levels of parents and identifying the greatest environmental stressor by understanding the aspects of infants, parents and the environment that can cause stress may be useful in assisting the health personnel in understanding their importance and in improving the quality of care. The objective of the study was to quantify stress levels of parents of babies admitted in NICU and compare the sources of stress for mothers and fathers.Methods: This was a cross-sectional, observational, hospital based study where stress levels were assessed using Parental Stressor Scale: neonatal intensive care unit (PSS: NICU) questionnaire among parents of 400 newborn admitted in NICU. Stress was quantified using 5 point Likert scale from 1 (not at all stressful) to 5 (extremely stressful). The overall stress levels were calculated for each subscale and total scale and compared.Results: NICU environment is moderately stressful for both mother and father. The highest score was in the field of Relationship with the baby and parental role for mothers as well as for fathers. Mothers had significantly higher stress scores for each subscale and the total scale compared to fathers.Conclusions: NICU parents are under significant stress and this is need of time to give family centered care.
Augmented BMI and waist to height ratio as screening tools for overweight and obesity among school going children aged 5 to 15 years
Authors: C. B. Ushakiran , Jagadeeshwara Sowmya , Lingaraju Bharathi 
Published: December 2016

Background: Worldwide raising trend in obesity among children is causing serious public health concerns and in developing countries it is threatening the viability of basic health care delivery. The objective of this study was to screen for overweight and obesity among school going children using the established methods as well as the newer screening tools and to compare the efficacy of the various screening toolsMethods: Prospective cross sectional study was conducted various government and non-government schools within city limits. And participants involves 1000 children in the age group of 5 to 15 years who met the predefined criteria were selected by purposive sampling.Results: Using BMI as a screening tool, 6.3% were identified as overweight and 5.8% as obese. Using Waist circumference alone, 5.2% were identified as overweight and 4.5% as obese. 13.8% and 5% were identified as overweight and obese respectively by waist circumference to height ratio. Using augmented BMI, 14.7% were identified as overweight and 4.3% as obese.Conclusions: Using WHTR and Augmented BMI, larger percentage of children were identified as overweight while the percentage of children identified as obese remained similar to using BMI or Waist circumference alone.
A cross-sectional study on depression among school going adolescent girls in Barabanki district, Uttar Pradesh, India
Authors: Shukla Nirpal Kaur , Shukla Mukesh , Ahmad Siraj , Shukla Ram , Khan Zainab 
Published: December 2016

Background: Depression is one of the common and ignorant psychiatric problems in adolescents now days. It has profound adverse effect on their physical as well as mental health. The objective of this study was to study the prevalence of depression among school going adolescent girls.Methods: A cross sectional study was conducted among 336 school going adolescent girls in Barabanki district from June 2016 to September 2016. Multistage sampling was used to enroll the study subjects. Bio-social parameters such as age, socioeconomic status etc. were assessed by direct interview of adolescent girl as well as its confirmation with school records. Six items KADS (Kutcher Adolescent Depression Scale) was used for assessment of depression among adolescent girl.Results: Out of 336 adolescent girls screened 18.7% were found positive for depression. Lower socio-economic status was found as one of the independent predictor of depression. Girls belonging to lower socioeconomic groups (odds ratio ([OR] 2.08; 95% confidence interval [CI] 1.18-3.21; p = 0.03) were more susceptible for depression. However on multiple logistic regression no statistical association was observed between depression with respect to age group, class, religion, caste and mothers education, and type of family (p>0.05).Conclusions: The study highlights need for timely diagnosis and treatment of problem through school based periodic screening programmes. There is also need of increasing awareness among teachers and parents about depression.
Effectiveness of lifestyle modification package among overweight and obese adolescent girls between 15-19 years with polycystic ovarian syndrome
Authors: Nair Anju Krishnan , Nambisan Bindu , Radha Sreekumary , Leelamma Jayasree 
Published: December 2016

Background: Polycystic ovarian syndrome (PCOS) is the most common female endocrine disorder which is often diagnosed during late adolescence, with anovulation and hyperandrogenism. Adolescent girls with PCOS, are at an increased risk for the development of type 2 diabetes mellitus and metabolic syndrome. Early diagnosis and early intervention may prevent long term sequelae and improve quality of life. The objectives were to study the effectiveness of lifestyle modification package among overweight and obese adolescent girls between 15-19 years with polycystic ovary syndrome (PCOS).Methods: In this study 144 adolescent girls (postmenarchal by 2 years) diagnosed as PCOS as per Rotterdam criteria after ruling out other causes of menstrual abnormality listed in the exclusion criteria, were selected. Informed consent taken from the participant or their parent if less than 18 years. Their anthropometric measurements and their menstrual cycles recorded at the beginning of the study and a lifestyle modification package including dietary modification and exercise, given to each of them. Participants were followed up telephonically every month to know their compliance towards the intervention program along with reinforcement of the package. After 6 months of intervention they were reviewed to assess the effectiveness of the intervention package.Results: Significant weight loss was seen in 66.4% of the participants and15.2% had weight stabilization (weight gain <1.5kg). There was significant change in BMI with mean change in BMI 1.9. 58.4% of the girls improved their menstrual cycle after 6 months. There was significant reduction in body fat% and W/H ratio.Conclusions: Lifestyle modification is a simple, cost effective treatment in the management of overweight and obese adolescent PCOS in improving their BMI and regularization of menstrual cycles.
A community based study on prevalence of obesity among urban population of Shivamogga, Karnataka, India
Authors: Nagendra Kanchana , C. Nandini , Belur Mangala 
Published: December 2016

Background: Obesity is a most prevalent malnutrition all over the world. It is estimated by the WHO that globally, over 1 billion (16%) adults are overweight and 300 million of these (5%) are obese. The highest rise in the number of obese is noted in the countries with fast growing economies especially of South East Asia. In India the prevalence of obesity is 12.6% in women and 9.3% in men. In other words, more than a 100 million individuals are obese in India. Objectives: To assess the prevalence of obesity in urban population of Shivamogga.Methods:A cross sectional study was conducted in Urban Shivamogga Study was conducted during February 1st to July 30th 2016 for 6 months. Data was collected from house hold members aged 15-64 years. The calculated sample size was 2000. Subjects were interviewed using a prestructured and pretested questionnaire adopted from WHO STEPS I and II, approaches for non-communicable diseases risk factors surveillance, after modifying to suit the local requirements (questions about Obesity and overweight were considered for study).Results: The prevalence of high BMI among study subjects was nearly fifty percent (45.6%). The prevalence of obesity in the study subjects was 31.6%, the prevalence was more in females (34.9%) compared to males (28.4%). The prevalence of central/ abdominal type of obesity was 41.2%.Conclusions:This community based study demonstrated high prevalence of obesity and overweight among the productive population of urban Shivamogga.