bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular breeding and genomics.
Authors: Font i Forcada C. , Sánchez-Pérez R. , Eduardo I. , Wu ShuBiao Wu ShuBiao , Fernández i Martí Á. 
Published: July 2017

Abstract

This chapter describes several types of DNA markers, each of which has different advantages/disadvantages which make them more or less desirable to use in certain applications (highly discriminative and environmentally stable, inexpensive, repeatable across different tissues and co-dominant): restriction fragment length polymorphism, random amplified polymorphic DNA, amplified fragment length polymorphism, simple sequence repeat microsatellites, and single nucleotide polymorphism. Their application in almond breeding and the impact of advances in modern molecular biological techniques, such as high-throughput sequencing and microarray systems, are discussed.
Almond water requirements.
Authors: Doll D. 
Published: July 2017

Abstract

This chapter discusses the irrigation requirements of an almond orchard, and describes the impacts of drought stress on almond vegetative growth, in-season kernel and fruit bud development, as well as yield. The management of orchard irrigation in water-limited environments is also discussed. Additional factors and considerations of water management are presented, discussing the effects of crop load, negative effects of canopy reduction, increasing soil salinity from reduced water quantity or quality, cultivar influences on water requirements, micro-irrigation systems and timing of water applications, reduction of water losses through evaporation, removal of the cover crop, minimal impacts of anti-transpirants, reduction in nitrogen applications, and insect management.
Almond pests.
Authors: Zalom F. G. , Núñez E. , Baldwin R. A. 
Published: July 2017

Abstract

This chapter aims to provide an overview of current knowledge on major pests affecting almond which is intended to be applicable worldwide. The chapter includes two main groups of pests: arthropods and vertebrates. The information presented is based on published sources as well as the authors' experience. It is divided into two sections relating to differences between the two groups of pests. The first section addresses arthropod species, including insects and mites, while the second section addresses vertebrate pests. The damages they caused to the crop are described, as well as their management strategies.
Chemical composition of almond nuts.
Authors: Kodad O. 
Published: July 2017

Abstract

This chapter summarizes the current knowledge of the almond kernel chemical composition (lipids, fatty acids, vitamins, phytosterols, minerals, protein and amino acids, phenols, carbohydrates and fibres) and the factors affecting its variability, which include cultivar/genotype, environmental conditions of the growing region and irrigation strategies. The biochemical constituents of almond hulls and shells are also described.
World almond market.
Authors: Ryan N. T. 
Published: July 2017

Abstract

In order to make good almond marketing decisions, it is important to have a comprehensive understanding of the world almond market and how it works. This chapter looks at the history and growth of the almond market, its structure and behaviour, then some of the specific decisions a grower or processor makes within this context, and finally ways to minimize risk in an almond market known for volatile prices. Growing almonds comes with financial risk because of the variability of market prices from one crop year to the next, as well as within an individual crop year. This market price risk is counterbalanced by the many factors that have favoured the growth of the world market and the ability of California (USA) growers to not only remain competitive but to dominate the world market. Factors responsible for this world market growth and California's advantages are enumerated.
Resisting for other reasons
Authors: Silvermint Daniel 
Published: July 2017

AbstractDoes a victim have to intend to resist oppression in order to discharge her obligation to do so, or is it sufficient to resist oppression intentionally in the course of pursuing other plans and projects of importance to her? I argue that resisting intentionally can be sufficient: given the ways that oppression interferes with the lives of victims, trying to counteract that interference by living the life you want is genuine resistance. Requiring that victims have justice-oriented or agency-preserving reasons before their actions count as resistance will distort or miss a wide range of everyday responses to oppressive burdens.
C. G. Jung on plagiarism in Pierre Benoît’s L’Atlantide
Authors: Fike Matthew A. 
Published: July 2017

ABSTRACTJung explained the possible plagiaristic relationship between Henry Rider Haggard’sSheand Pierre Benoît’sL’Atlantideas either cryptomnesia or archetypal inspiration, but he was misinformed about the case and unfamiliar with Benoît’s life. This essay critiques Jung’s statements about Benoît and then considers the case for plagiarism that was published inThe French Quarterlyin 1919–1920. Neither the typical reply – thatL’Atlantidereflects the author’s African experience and historical knowledge – nor the reading of the novel that arose from Jung’s 1925 seminar adequately refutes the plagiarism charge. A depth-psychological reading ofL’Atlantideshows the danger of seeking the anima archetype itself rather than experiencing the anima in a relationship with an available woman. But even if literary analogies, including the Circe myth, suggest that Haggard and Benoît may have tapped into the same archetypal vein, the novels’ similarities and verbal echoes cannot be dismissed outright.
Key comparison BIPM.RI(I)-K3 of the air-kerma standards of the NIST, USA and the BIPM in medium-energy x-rays
Authors: Burns D T , Kessler C , O'Brien M , Minniti R 
Published: July 2017

A key comparison has been made between the air-kerma standards of the NIST, USA and the BIPM in the medium-energy x-ray range. The results show the standards to be in agreement at the level of the standard uncertainty of the comparison of 3.8 parts in 103, except at 250 kV where the difference is 1.5 times the standard uncertainty. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
International comparison CCQM-K111.1—propane in nitrogen
Authors: van der Veen Adriaan M H , van der Hout J Wouter , Ziel Paul R , Jozela Mudalo , Tshilongo James , Ntsasa Napo G , Botha Angelique 
Published: July 2017

This key comparison aims to assess the core capabilities of the participants in gas analysis. Such competences include, among others, the capability of preparing Primary Standard gas Mixtures (PSMs), performing the necessary purity analysis on the materials used in the gas mixture preparation, the verification of the composition of newly prepared PSMs against existing ones, and the capability of calibrating the composition of a gas mixture. According to the Strategy for Key Comparisons of the Gas Analysis Working Group, this subsequent key comparison is classified as a track B key comparison, which means that the results of this key comparison can be used to underpin calibration and measurement capabilities for propane under the default scheme.
The artefact was a binary mixture of propane in nitrogen at a nominal amount-of-substance fraction level of 1000 μmol/mol. The values and uncertainties from the gravimetric gas mixture preparation were used as key comparison reference values (KCRVs). Each transfer standard had its own KCRV. The result of the participating laboratory is consistent with the key comparison reference value within the respective expanded uncertainties and deviates less than 0.1 %.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
FAF-Drugs4: free ADME-tox filtering computations for chemical biology and early stages drug discovery
Authors: Lagorce David , Bouslama Lina , Becot Jerome , Miteva Maria A , Villoutreix Bruno O 
Published: July 2017

Abstract

Motivation
Identification of small molecules that could be interesting starting points for drug discovery or to investigate a biological system as in chemical biology endeavours is both time consuming and costly. In silico approaches that assist the design of quality compound collections or help to prioritize molecules before synthesis or purchase are therefore valuable. Here quality refers to the selection of molecules that pass one or several selected filters that can be tuned by the users according to the project and the stage of the project. These filters can involve prediction of physicochemical properties, search for toxicophores or other unwanted chemical groups.

Results
FAF-Drugs4 is a novel version of our online server dedicated to the preparation and annotation of compound collections. The tool is now faster and several parameters have been optimized. In addition, a new service referred to as FAF-QED, an implementation of the quantitative estimate of drug-likeness method, is now available.

Availability and implementation
The server is available at http://fafdrugs4.mti.univ-paris-diderot.fr.

Supplementary information
Supplementary data are available at Bioinformatics online.
First detection of HC515N in the interstellar medium
Authors: Taniguchi Kotomi , Saito Masao 
Published: July 2017

Abstract
We report the first detection of HC515N with the J = 9–8 rotational line from the cyanopolyyne peak in Taurus Molecular Cloud-1 (TMC-1 CP) using the 45 m radio telescope of the Nobeyama Radio Observatory. The column density of HC515N is derived to be (1.9 ± 0.5) × 1011 cm−2 (1σ). We apply the double-isotope method to derive the 14N/15N ratios of HC5N and HC3N in TMC-1 CP. The 14N/15N ratios are calculated to be 344 ± 53 and 257 ± 54 for HC5N and HC3N, respectively. The 14N/15N ratio of HC5N is lower than the elemental ratio in the local interstellar medium (∼440) and slightly higher than that of HC3N in TMC-1 CP. Since HC3N is formed via the neutral–neutral reaction between C2H2 and CN, the slightly higher 14N/15N ratio of HC5N may support our previous suggestions that the main formation mechanism of HC5N is the ion–molecule reactions between hydrocarbon ions (C5H$_{n}^{+}$) and nitrogen atoms.
Electronic Cigarette Use Among Counseled Tobacco Users Hospitalized in 2015
Authors: De Genna Natacha M. , Ylioja Thomas , Schulze Anna E. , Manta Christine , Douaihy Antoine B. , Davis Esa M. 
Published: July 2017

Objectives:
Few studies have examined the prevalence of electronic cigarette use among the inpatient population regardless of the patients’ cessation goals. The objectives of this study were to examine the prevalence of electronic cigarette use among counseled tobacco users admitted to 2 academic hospitals.

Methods:
Cross-sectional data of hospitalized adult tobacco users who were admitted between January 1, 2015 and December 31, 2015 and who received bedside tobacco cessation counseling from a tobacco treatment service counselor were examined. Demographic and smoking history items were compared as a function of electronic cigarette use using chi-square and independent t tests. Logistic regression was used to test independent associations with electronic cigarette use.

Results:
Of 2194 hospitalized tobacco users counseled, 22% had used an electronic cigarette. Most of these patients used electronic cigarettes to quit or reduce use of combustible cigarettes. Adjusted odds of electronic cigarette use were higher for females (adjusted odds ratio [AOR] 0.60 for male patients, 95% confidence interval [CI] 0.47–0.76), younger patients (AOR 0.98 for older patients, 95% CI 0.97–0.99), and individuals who initiated tobacco use earlier in life (AOR 0.97 for later smoking initiation, 95% CI 0.95–0.99).

Conclusions:
Screening hospitalized cigarette smokers for electronic cigarette use offers an opportunity to counsel all patients on evidence-based quit aids. Young, female patients are most likely to use electronic cigarettes and may benefit most from directed discussions about electronic cigarette use and Federal Drug Administration-approved cessation methods during smoking cessation counseling.
Auditory and Audiovisual Close Shadowing in Post-Lingually Deaf Cochlear-Implanted Patients and Normal-Hearing Elderly Adults
Authors: Scarbel Lucie , Beautemps Denis , Schwartz Jean-Luc , Sato Marc 
Published: July 2017

Objectives:
The goal of this study was to determine the effect of auditory deprivation and age-related speech decline on perceptuo–motor abilities during speech processing in post-lingually deaf cochlear-implanted participants and in normal-hearing elderly (NHE) participants.

Design:
A close-shadowing experiment was carried out on 10 cochlear-implanted patients and on 10 NHE participants, with two groups of normal-hearing young participants as controls. To this end, participants had to categorize auditory and audiovisual syllables as quickly as possible, either manually or orally. Reaction times and percentages of correct responses were compared depending on response modes, stimulus modalities, and syllables.

Results:
Responses of cochlear-implanted subjects were globally slower and less accurate than those of both young and elderly normal-hearing people. Adding the visual modality was found to enhance performance for cochlear-implanted patients, whereas no significant effect was obtained for the NHE group. Critically, oral responses were faster than manual ones for all groups. In addition, for NHE participants, manual responses were more accurate than oral responses, as was the case for normal-hearing young participants when presented with noisy speech stimuli.

Conclusions:
Faster reaction times were observed for oral than for manual responses in all groups, suggesting that perceptuo–motor relationships were somewhat successfully functional after cochlear implantation and remain efficient in the NHE group. These results are in agreement with recent perceptuo–motor theories of speech perception. They are also supported by the theoretical assumption that implicit motor knowledge and motor representations partly constrain auditory speech processing. In this framework, oral responses would have been generated at an earlier stage of a sensorimotor loop, whereas manual responses would appear late, leading to slower but more accurate responses. The difference between oral and manual responses suggests that the perceptuo–motor loop is still effective for NHE subjects and also for cochlear-implanted participants, despite degraded global performance.
Poor Agreement Between Imaging and Histologic and Colonoscopy Findings in Pediatric Patients
Authors: Chapa‐Rodriguez Adrian , Bhatia Tavleen , Buckley Andrew , Baker Susan S. , Baker Robert D. , Alkhouri Razan H. 
Published: July 2017

ABSTRACTBackground:Computed tomography scans (CTs), more recently magnetic resonance imaging, are often used to assess the gastrointestinal tract in patients complaining of abdominal pain. We aim to determine the strength of agreement among abdominal imaging, endoscopic, and histologic findings.Methods:Retrospective chart review of pediatric patients who underwent colonoscopy between January 1, 2012, and December 31, 2014, at Women and Children's Hospital of Buffalo. Patients who had abdominal and pelvic CTs or magnetic resonance imaging within 30 days before or after a colonoscopy were included.Results:One hundred two patients were included: mean age 12.7 ± 3.8 years, 66% girls. A total of 109 imaging studies were performed. Overall 61% of imaging studies were abnormal. The most frequent intestinal radiological findings were colonic wall thickening (CWT) (55%) and colonic wall enhancement (CWH) (24%). Free fluid (20%) and fat stranding (18%) were the most common extra‐intestinal findings. Imaging studies agreed with histology in 81% and with colonoscopy in 75% with a moderate strength of agreement (k: 0.59 and 0.466, respectively). CWT agreed with histology in 74% with a moderate strength of agreement (k: 0.47). History of weight loss (OR 5.35, P = 0.041), chronic diarrhea (OR 4.22, P = 0.014), a positive lactoferrin (OR 7.00, P = 0.011), and presence of CWT on imaging study (OR 5.20, P = 0.001) were predictive of having abnormal histology.Conclusions:The strength of agreement among imaging, endoscopic, and histologic findings was suboptimal. Colonoscopy and imaging are both likely to be necessary in patients with suspected inflammatory bowel disease. Although colonoscopy may be superior in diagnosis of colitis, imaging may provide more information regarding small bowel disease.
Cystic Fibrosis–related Liver Disease
Authors: Debray Dominique , Narkewicz Michael R. , Bodewes Frank A.J.A. , Colombo Carla , Housset Chantal , de Jonge Hugo R. , Jonker Johan W. , Kelly Deirdre A. , Ling Simon C. , Poynard Thierry , Sogni Philippe , Trauner Michael , Witters Peter , Baumann Ulrich , Wilschanski Michael , Verkade Henkjan J. 
Published: July 2017

ABSTRACTObjectives:Hepatobiliary complications are a leading cause of morbidity and mortality in cystic fibrosis (CF) patients. Knowledge of the underlying pathological aspects and optimal clinical management is, however, sorely lacking.Methods:We provide a summary of the lectures given by international speakers at the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) monothematic conference on cystic fibrosis–related liver disease (CFLD) held in Paris in January 2016, to discuss the status of our current knowledge of liver disease in CF patients, to define the critical areas that need to be addressed, and to resolve actions to elucidate relevant mechanisms of disease to optimise future therapeutic options.Conclusions:The need for a universal consensus on the definition of CFLD to clarify disease stage and to identify relevant biomarkers to assess disease severity was highlighted. A deeper understanding of the pathophysiology and prognostic factors for the long‐term evolution of CFLD is fundamental to move forward and has a strong bearing on identifying potential treatments. Novel experimental models and new treatment options under investigation are discussed and offer hope for the near future of CFLD.
Real‐life Anti‐tumor Necrosis Factor Experience in More Than 500 Patients
Authors: Merrick Victoria M. , Mortier Kajal , Williams Linda J. , Muhammed Rafeeq , Auth Marcus K.H. , Elawad Mamoun , Fell John M.E. , Beattie R. Mark , Loganathan Sabarinathan , Torrente Franco , Morris Mary‐Anne , Charlton Charles , Croft Nick M. , Rodrigues Astor , Furman Mark , Vadamalayan Babu , Jenkins Huw , Zamvar Veena , Mitton Sally G. , Chong Sonny , Cosgrove Mike , Akobeng Anthony , Wilson David C. , Russell Richard K. 
Published: July 2017

ABSTRACTObjective:The aim of this study was to measure the effectiveness, safety, and use of anti‐tumor necrosis Factor (TNF) therapy in pediatric inflammatory bowel disease in the United Kingdom (UK).Methods:Prospective UK audit of patients newly starting anti‐TNF therapy. Disease severity was assessed using Physician Global Assessment +/or the Paediatric Crohn Disease Activity Index.Results:A total of 37 centers participated (23/25 specialist pediatric inflammatory bowel disease sites). A total of 524 patients were included: 429 with Crohn disease (CD), 76 with ulcerative colitis (UC), and 19 with IBD unclassified (IBDU). Eighty‐seven percent (488/562) of anti‐TNF was infliximab; commonest indication was active luminal CD 77% (330/429) or chronic refractory UC/IBDU 56% (53/95); 79% (445/562) had concomitant co‐immunosuppression. In CD (267/429 male), median time from diagnosis to treatment was 1.42 years (interquartile range 0.63–2.97). Disease (at initiation) was moderate or severe in 91% (156/171) by Physician Global Assessment compared to 41% (88/217) by Paediatric Crohn Disease Activity Index (Kappa (κ) 0.28 = only “fair agreement”; P < 0.001.Where documented, 77% (53/69) of patients with CD responded to induction; and 65% (46/71) entered remission. A total of 2287 infusions and 301.96 years of patient’ follow‐up (n = 385) are represented; adverse events affected 3% (49/1587) infliximab and 2% (2/98) adalimumab infusions (no deaths or malignancies). Peri‐anal abscess drainage was less common after anti‐TNF initiation (CD), that is 26% (27/102) before, 7% (3/42) after (P = 0.01); however, pre and post anti‐TNF data collection was not over equal time periods.Conclusions:Anti‐TNFs are effective treatments, usually given with thiopurine co‐immunosuppression. This study highlights deficiencies in formal documentation of effect and disparity between disease severity scoring tools, which need to be addressed to improve ongoing patient care.
Intervention for Feeding Difficulties in Children With a Complex Medical History
Authors: Marshall Jeanne , Hill Rebecca J. , Wallace Meagan , Dodrill Pamela 
Published: July 2017

ABSTRACTObjective:This study aimed to compare outcomes of different multidisciplinary feeding therapy approaches in children with feeding difficulties.Methods:Children aged 2 to 6 years with feeding difficulties and a medically complex history (MC) were recruited. Children with feeding difficulties and a nonmedically complex history (NMC) were included as a comparison group. Participants attended a clinical assessment, and eligible participants were randomized to receive targeted feeding intervention incorporating either operant conditioning or systematic desensitization. Parents could elect to receive intervention in an intensive (10 sessions in a week) or weekly (10 sessions during 10 weeks) format. Both groups received immersive parent training. A review was completed 3 months post‐intervention.Results:In total, 98 participants were eligible to participate (MC, n = 43; NMC, n = 55). Data from 20 children from the MC group (47%) and 41 children from the NMC group (75%) were included in the final analysis. Clinically significant improvements were observed following both arms of therapy, consistent with previous research. Parents of children in the MC arm were significantly more likely to elect for intensive intervention than weekly (MC = 12/20, 60%; 12/41, 29%; P = 0.02).Conclusions:Both therapy protocols were considered clinically effective. The difference in attrition rates between the etiological groups suggests primary differences in how service delivery should be managed. Progress for the medically complex child may be slower while medical issues are stabilized, or while the focus for parents shifts to other developmental areas. In planning services for a medically complex group, therefore, it is essential that consideration be given to medical and family needs.