bluuebunny/crossref_metadata_2025_split huggingface dataset:
Silver-Russell Syndrome: A Review
Authors: Spiteri Bernice Sophie , Stafrace Yanika , Calleja-Agius Jean 
Published: August 2017

AbstractSilver-Russell syndrome (SRS) is a rare congenital imprinting disorder. The genetic findings in SRS patients are heterogeneous and often sporadic. However, chromosomes 7, 11, and 17 are consistently involved in all individuals who meet the strict diagnostic criteria of SRS. There are many clinical features characteristic of SRS; the most common are low birth weight, short stature, triangular face, clinodactyly, relative macrocephaly, ear anomalies, and skeletal asymmetry.
Geologia como uma ciência histórica da natureza
Authors: Potapova Marina 
Published: August 2017

A geologia como ciência teórica está sem dúvida passando por uma de suas crises de crescimento. Isto é visto, em particular, nas contribuições contraditórias sobre seu objeto, conteúdo e método. Ouvem-se proposições de que a noção de geologia como uma ciência que trata da história da Terra há muito tornou-se antiquada, que a Geofísica, a Geoquímica e outras são as únicas ciências teóricas da Terra.
Wiegand, Patrick. Learning and Teaching with maps Londonn: Routledge, 2006
Authors: Oliveira Adriano Rodrigo 
Published: August 2017

O livro Learning and teaching with maps, de autoria do professor Patrick Wiegand, pesquisador da didática da geografia e cartografia na Faculdade de Educação da Universidade de Leeds, na Inglaterra, faz uma extensa revisão bibliográfica de estudos e publicações em língua inglesa relacionados ao ensino e à aprendizagem de mapas no contexto escolar; temática de relevância para professores e pesquisadores do ensino de geografia, geociências e pedagogia.
Relato Final do VI Encontro do Fórum Nacional de Cursos de Geologia, 2006
Authors: Assis José Fernando Pina , Fantinel Lucia , Carneiro Celso Dal Ré 
Published: August 2017

O VI Encontro do Fórum Nacional de Cursos de Geologia foi promovido entre os dias 30 de maio e 2 de junho de 2006, pelas seguintes universidades: Federal do Rio de Janeiro (UFRJ), Univ. Federal Rural do Rio de Janeiro (UFRRJ) e do Estado do Rio de Janeiro (UERJ) e pela Sociedade Brasileira de Geologia (SBGeo), nos institutos aos quais estão vinculados os cursos de Geologia das três instituições.
A astronomia, a moderna Geologia, e a profissão de geólogo no Brasil
Authors: Editorial Conselho 
Published: August 2017

A oportunidade aberta pela promulgação do Ano Internacional de Astronomia em 2009 expande para a geologia, e em particular para os especialistas dedicados à geologia planetária, campos notáveis de evolução e desenvolvimento conceitual. As sondas interplanetárias, os poderosos telescópios colocados em órbita da Terra e os incontáveis satélites de observação trazem conhecimentos surpreendentes a cada semana. Fica cada vez mais evidente o fato de serem absolutamente singulares as condições para desenvolvimento de vida, no minúsculo planeta que nos acolhe.
FORMAÇÃO DOS DIRIGENTES MUNICIPAIS DE EDUCAÇÃO DA UNIVERSIDADE FEDERAL DO TOCANTINS (PRADIME-UFT): gestão da educação municipal em foco
Authors: Cunha Célio da , Macedo Margareth Leber 
Published: August 2017

Na busca de levar conhecimento e contribuir com as gestões educacionais municipais, a Universidade Federal do Tocantins, através da Diretoria de Tecnologias Educacionais – DTE/UFT ofereceu e certificou as primeiras turmas de Especialização em Gestão da Educação Municipal do Programa de Apoio aos Dirigentes Municipais de Educação - PRADIME. O programa utilizou a educação a distância para aproximar o público alvo e fez uso das tecnologias educacionais como agente de democratização do conhecimento. Esse artigo relata a execução da especialização que ocorreu nos estados do Tocantins e Maranhão, com a abordagem das questões da gestão municipal, política pública e educação a distância.
Risk Factors for Prolonged Opioid Use Following Spine Surgery, and the Association with Surgical Intensity, Among Opioid-Naive Patients
Authors: Schoenfeld Andrew J. , Nwosu Kenneth , Jiang Wei , Yau Allan L. , Chaudhary Muhammad Ali , Scully Rebecca E. , Koehlmoos Tracey , Kang James D. , Haider Adil H. 
Published: August 2017

Background:
There is a growing concern that the use of prescription opioids following surgical interventions, including spine surgery, may predispose patients to chronic opioid use and abuse. We sought to estimate the proportion of patients using opioids up to 1 year after discharge following common spinal surgical procedures and to identify factors associated with sustained opioid use.

Methods:
This study utilized 2006 to 2014 data from TRICARE insurance claims obtained from the Military Health System Data Repository. Adults who underwent 1 of 4 common spinal surgical procedures (discectomy, decompression, lumbar posterolateral arthrodesis, or lumbar interbody arthrodesis) were identified. Patients with a history of opioid use in the 6 months preceding surgery were excluded. Posterolateral arthrodesis and interbody arthrodesis were considered procedures of high intensity, and discectomy and decompression, low intensity. Covariates included demographic factors, preoperative diagnoses, comorbidities, postoperative complications, and mental health disorders. Risk-adjusted Cox proportional hazard models were used to evaluate the time to opioid discontinuation.

Results:
This study included 9,991 patients. Eighty-four percent filled at least 1 opioid prescription on discharge. At 30 days following discharge, 8% continued opioid use; at 3 months, 1% continued use; and at 6 months, 0.1%. In the adjusted analysis, the low-intensity surgical procedures were associated with a higher likelihood of discontinuing opioid use (discectomy: hazard ratio [HR] = 1.43, 95% confidence interval [CI] = 1.36 to 1.50; and decompression: HR = 1.34, 95% CI = 1.25 to 1.43). Depression (HR = 0.84, 95% CI = 0.77 to 0.90) was significantly associated with a decreased likelihood of discontinuing opioid use (p < 0.001).

Conclusions:
By 6 months following discharge, nearly all patients had discontinued opioid use after spine surgery. As only 0.1% of the patients continued opioid use at 6 months following surgery, these results indicate that spine surgery among opioid-naive patients is not a major driver of long-term prescription opioid use. Socioeconomic status and pre-existing mental health disorders may be factors associated with sustained opioid use following spine surgery.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
The CD45lowCD271high Cell Prevalence in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative Therapy
Authors: El-Jawhari Jehan J. , Cuthbert Richard , McGonagle Dennis , Jones Elena , Giannoudis Peter V. 
Published: August 2017

Background:
Bone marrow aspirates and concentrates are increasingly being used for musculoskeletal regenerative therapies, providing bone and cartilage progenitors. However, the quality of these bone marrow samples remains imprecise within clinical settings. As there is a need for the development of these therapies, a method of counting CD45lowCD271high cells was optimized and tested as an indicator of bone marrow sample quality.

Methods:
Bone marrow aspirates were collected from 54 donors (28 male and 26 female; median age of 48 years). The reagent concentrations were optimized for fast staining, and an acoustic-focusing flow cytometer (Attune) was used to enable automated CD45lowCD271high cell counting in bone marrow aspirates, bone marrow concentrates, and samples loaded onto a collagen scaffold. The CD45lowCD271high cell counts were compared with those obtained using another flow-cytometry-based method (LSR II) and with connective tissue progenitor (CTP) counts quantified using a colony forming unit-fibroblast (CFU-F) assay.

Results:
The optimized method enabled the counting of CD45lowCD271high cells within only 15 minutes. The quantified cell counts (median, 1,520; range, 96 to 20,992 cells/mL of bone marrow) were positively correlated with the CTP counts (p < 0.0001; r = 0.7237). In agreement with CFU-F and LSR II-based assays, the CD45lowCD271high cell counts quantified using the Attune-based method decreased with age in the samples from female but not male donors (p = 0.0015 and p = 0.3877, respectively). A significant increase in CD45lowCD271high cell counts was detected following bone marrow concentration (mean, 5-fold; 95% confidence interval [CI], 3.6 to 7.2-fold). Additionally, the number of CD45lowCD271high cells attached to the collagen scaffold was positively correlated with the number of progenitor cells that survived on the scaffold after 2-week culture (p = 0.0348).

Conclusions:
An assay for counting CD45lowCD271high cells may provide a useful measurement of bone marrow quality. While the specificity of this measurement of CD45lowCD271high cells remained low in our experimental conditions, CD45lowCD271high cell counts were positively and modestly correlated with the prevalence of CTPs.

Clinical Relevance:
A fast and automated assessment of bone marrow aspirate/concentrate quality using CD45lowCD271high cell counting may be a useful tool for improving the quality of regenerative therapy.
Tracking Cumulative Radiation Exposure in Orthopaedic Surgeons and Residents
Authors: Gausden Elizabeth B. , Christ Alexander B. , Zeldin Roseann , Lane Joseph M. , McCarthy Moira M. 
Published: August 2017

Background:
The purpose of this study was to determine the amount of cumulative radiation exposure received by orthopaedic surgeons and residents in various subspecialties. We obtained dosimeter measures over 12 months on 24 residents and 16 attending surgeons.

Methods:
Monthly radiation exposure was measured over a 12-month period for 24 orthopaedic residents and 16 orthopaedic attending surgeons. The participants wore a Landauer Luxel dosimeter on the breast pocket of their lead apron. The dosimeters were exchanged every rotation (5 to 7 weeks) for the resident participants and every month for the attending surgeon participants. Radiation exposure was compared by orthopaedic subspecialty, level of training, and type of fluoroscopy used (regular C-arm compared with mini C-arm).

Results:
Orthopaedic residents participating in this study received monthly mean radiation exposures of 0.2 to 79 mrem/month, lower than the dose limits of 5,000 mrem/year recommended by the United States Nuclear Regulatory Commission (U.S. NRC). Senior residents rotating on trauma were exposed to the highest monthly radiation (79 mrem/month [range, 15 to 243 mrem/month]) compared with all other specialty rotations (p < 0.001). Similarly, attending orthopaedic surgeons who specialize in trauma or deformity surgery received the highest radiation exposure of their peers, and the mean exposure was 53 mrem/month (range, 0 to 355 mrem/month).

Conclusions:
Residents and attending surgeons performing trauma or deformity surgical procedures are exposed to significantly higher doses of radiation compared with all other subspecialties within orthopaedic surgery, but the doses are still within the recommended limits.

Clinical Relevance:
The use of ionizing radiation in the operating room has become an indispensable part of orthopaedic surgery. Although all surgeons in our study received lower than the yearly recommended dose limit, it is important to be aware of how much radiation we are exposed to as surgeons and to take measures to further limit that exposure.
MYXEDEMA MADNESS: AN INTRIGUING CASE OF DEPRESSION IN HYPOTHYROIDISM
Authors: Patil Navin , Rao Karthik , Naaz Humeera , Ommurugan Balaji , Baiju Gayathri , Naik Ananda , Sira Hargun Singh 
Published: August 2017

Hypothyroidism is a clinical syndrome due to deficiency of thyroid hormone. Thyroid hormone is responsible for maintaining the brain hemostasis and helps in central nervous system global development. There have been studies on the association of psychiatric illness with thyroid deficiency and strikingly found to be presenting feature of hypothyroidism in many patients. Literature evidence also says that underlying hypothyroidism may lead to failure of psychiatric treatment. Hence, we report a case of hypertensive patient on medications started with antidepressants and antipsychotics after being diagnosed of depression but was found to be resistant to psychiatric medications and later successfully treated with levothyroxine for underlying hypothyroidism with myxedema.
G-QUADRUPLEX LIGANDS AS STABILIZER TARGETING TELOMERASE ENZYME AS ANTI CANCER AGENTS
Authors: Cn Hemalatha , M Vijey Aanandhi , M Vijey Aanandhi 
Published: August 2017

The human telomere stabilization with G-Quadruplex DNA tends to induce apoptosis. The molecular target of telomere cascade with a rigid molecular may show efficacious to treat cancer. The study of intercalation to human telomeric DNA with proposed ligand can be evaluated by the help of biophysical studies and biological studies. G-Quadruplex is one of the key epigenetic episodes of eukaryotes and prokaryotes, generally found in the telomeric end region, immunoglobulin switch recombination and the lagging strand of the DNA. These chemotherapeutic advances are not enough to maintain a life expectancy of cancer affected patients. A number of G-Quadruplex ligands such as acridine, perylene, and anthraquinones have been synthesized reported and evaluated them for the inhibitor activity. Therefore, translational research can pave the novel prospect to treat cancer in a fundamental way. In that connection, basic research showed G-Quadruplex phenomenon of DNA, which is having a great impact in this chemotherapy.
A Gestão e a Avaliação de Tecnologias em Saúde no Paraná: desafios e propostas para a SESA e para o setor de saúde paranaense*
Authors: Remondi Felipe , Lazarotto Helder , Almeida Marcio José de , Caputo Neto Michele 
Published: August 2017

Texto preliminar, preparado para subsidiar discussões a respeito da necessidade de iniciar/fortalecer a ATS no estado. Curitiba, junho/2017.
Sistemas aerogravimétricos gradiométricos 3D-FTG e Falcon na exploração de minério de ferro
Authors: Galbiatti Henry , Braga Marco Antonio , Carlos Dionísio Uendro , Sousa Rodrigo Rocha de 
Published: August 2017

O presente trabalho de pesquisa apresenta uma descricão das características dos sistemas 3D-FTG (Full Tensor Gravity Gradiometer ) e AGG Falcon (AirborneGravity Gradiometer ), assim como as fases do planejamento e controle de qualidade dos dados levantados com esses dois sistemas. O 3D-FTG é atualmente a única tecnologia aérea existente capaz de medir as cinco componentes independentes do tensor do gradiente de gravidade. O sistema Falcon mede uma das componentes do tensor e também a curvatura (composição de duas componentes será mostrada a frente), os dois sistemas podem ser utilizados tanto para levantamentos detalhados como regionais. As aquisições de dados com os sistemas 3D-FTG e Falcon, que serão apresentadas, foram realizadas sobre um dos depósitos de minério de ferro de Carajás, Serra Leste, no estado do Pará, Brasil. Mineralizações de óxido de ferro são largamente controladas por estruturas crustais e locais, como zonas de cisalhamento,zonas de falha e contatos litológicos. Um controle cartográfico preciso destas estruturas, para a utilização de aerolevantamentos gravimétricos gradiométricosé muito importante para se encontrar concentrações consideráveis e econômicas destes tipos de depósitos.
Geoelectrical prospection of disseminated sulfide mineral occurrences in Camaquã Sedimentary Basin, Rio Grande do Sul State, Brazil
Authors: Moreira César Augusto , Lopes Syngra Machado , Schweig Camila , Seixas Adriano Da Rosa 
Published: August 2017

The mineral exploration is a complex activity that should involve a combination of direct and indirect techniques of geological investigation. The growing demand for base metals in the national and international market provides the revaluation of mineral occurrences that can become deposits and mines. This paper presents the results of the electrical resistivity and induced polarization geophysical methods in azimuthal arrangement, applied in a mineral occurrence of disseminated copper sulfides, previously studied through trenches and core drilling, located in the Camaquã Sedimentary Basin, Rio Grande do Sul State, Brazil. The inversion models indicate the coincidence of high chargeability and low resistivity values. The integration of geophysical data permitted the elaboration of 3D attributes visualization models for the mineralization enclosed in volcanic tuffs. The integrated geophysical and geological analysis indicates the potential of a new mineralized area.
STEREOTOMOGRAPHY FOR VELOCITY MODEL ESTIMATION IN SEISMIC IMAGING: APPLICATION TO REAL DATA FROM JEQUITINHONHA SEDIMENTARY BASIN
Authors: Terra Felipe A. , Costa Jessé C. , Bassrei Amin 
Published: August 2017

O imageamento sísmico em profundidade é um desafio em áreas geologicamente complexas, onde a velocidade sísmica apresenta variação lateral. Porém, para se obter sucesso no imageamento sísmico em profundidade é necessário que se tenha uma estimativa confiável do modelo de velocidade. A estereotomografia é uma ferramenta efetiva para se alcançar esse propósito. Também denominada de tomografia de inclinação, ela utiliza as vagarosidades e os tempos de trânsito selecionados de famílias de fonte comum e de receptor comum. Nós avaliamos uma alternativa da estereotomografia para a construção do modelo de velocidades. O algoritmo foi validado no conjunto de dados sintéticos Marmousoft e também em dados reais provenientes da Bacia do Jequitinhonha, Brasil, numa região de talude continental. Este conjunto de dados com complexidade estrutural demandou um controle de alta qualidade na seleção de eventos, numa escolha criteriosa dos parâmetros de regularização, e a atenuação de múltiplas de superfície livre. Os resultados tanto para os dados sintéticos como para os reais mostraram a viabilidade computacional e precisão do método. ABSTRACT. Seismic imaging in depth is a challenge in geologically complex areas, where the seismic velocity varies laterally. The estimation of a reliable velocity model is necessary in order to succeed in seismic depth imaging. Stereotomography is an effective tool to achieve this purpose. Also called slope tomography, it uses the slowness and picked traveltimes from reflection events picked in common source and common receiver gathers. We evaluate an alternative implementation of stereotomography for velocity model building. The algorithm was validated in the Marmousoft synthetic data set and also used for velocity model estimation in acontinental slope region, using real data from Jequitinhonha Basin, Brazil. This data set of structural complexity demanded a high quality control of event selection forpicking, judicious choice of regularization parameters and free surface multiple attenuation. The results for both the synthetic and real data have shown the computational feasibility and accuracy of this method.Keywords: stereotomography, regularization, Jequitinhonha Basin
SEISMIC TRAVELTIME TOMOGRAPHY APPLIED TO DATA FROM MIRANGA FIELD, RECÔNCAVO BASIN, BRAZIL
Authors: Rodrigues Vitor Hugo Serravalle Reis , Bassrei Amin 
Published: August 2017

ABSTRACT. The growing global demand for hydrocarbons has tested the limits of oil exploration and exploitation technologies. Among the seismic methods, tomography is an alternative means for high-resolution characterization of reservoirs, and it enables a more efficient...Keywords: reservoir characterization, traveltime tomography, seismic inversion, regularization, Recôncavo Basin. RESUMO. A crescente demanda mundial por hidrocarbonetos tem testado os limites das tecnologias de exploração e explotação de petróleo. Dentro dos métodos sísmicos, a tomografia surge como alternativa de caracterização de alta resolução dos reservatórios,...Palavras-chave: caracterização de reservatórios, tomografia de tempos de trânsito, inversão s´ísmica, regularização, Bacia do Recôncavo.
FULL WAVEFORM INVERSION USING AN EFFICIENT PRECONDITIONING METHOD FOR THE GRADIENT VECTOR APPLIED FOR DIFFERENT SOURCE SIGNATURES
Authors: Santos Peterson Nogueira , Pestana Reynam C. 
Published: August 2017

ABSTRACT. Full-waveform inversion (FWI) is a powerful method and it has been used successfully to invert subsurface parameters. It consists basically on the minimization of the difference between the predicted and observed data. However, its application using finite-difference schemes is limited to low frequency content and the increase of the range of higher frequency...Keywords: full waveform inversion, preconditioning method, rapid expansion method. RESUMO. Inversão de forma de onda completa (FWI) é um método poderoso e tem sido utilizado com sucesso para inverter parâmetros de subsuperfície. Consiste basicamente na minimização da diferença entre os dados previstos e observados.No entanto, sua aplicação usando esquemas de diferenças finitas é limitada ao conteúdo de baixa frequência e o aumento da banda...Palavras-chave: inversão completa da forma de onda, método de pré-condicionamento, método de expansão rápida.
MAGNETIC ANALYSIS OF ABAETÉ DIAMONDIFEROUS DISTRICT (MG) AND ITS POSSIBLE PRIMARY SOURCES
Authors: Silva Gisella Magalhães , Endo Issamu , Barbosa Maria Sílvia Carvalho 
Published: August 2017

ABSTRACT. This work studies the origin of the diamonds from the important mining region, Abaet´e Diamondiferous District (MG). The discovery of pipes with micro diamonds and/or crater facies kimberlites in the entire Alto Parana´ıba Igneous Province...Keywords: mineral prospecting, Euler Deconvolution, Alto Paranaíba Igneous Province. RESUMO. Este trabalho estuda a origem dos diamantes de uma importante região mineradora, o Distrito Diamantífero Abaeté (MG). A descoberta de kimberlitos com microdiamantes e/ou fácies de cratera em toda Província Ígnea do Alto...Palavras-chave: prospecção mineral, Deconvolução de Euler, Província Ígnea do Alto Paranaíba.
OBSERVATIONS OF SMALL-SCALE GRAVITY WAVES IN THE EQUATORIAL UPPER MESOSPHERE
Authors: Campos José André Vieira , Paulino Igo , Wrasse Cristiano Max , Medeiros Amauri Fragoso de , Paulino Ana Roberta , Buriti Ricardo Arlen 
Published: August 2017

ABSTRACT. Using airglow images collected at São João do Cariri (7.4◦S; 36.5◦W) from 2009 to 2010, the spectral characteristics and seasonality in the propagation direction of small-scale gravity waves were studied...Keywords: airglow, neutral wind, gravity waves, blocking diagram. RESUMO. Utilizando imagens de aeroluminecência coletadas por um imageador instalado em São João do Cariri (7,4◦S; 36,5◦W) no período de 2009 a 2010, foram estudadas as características espectrais bem como a sazonalidade na direção...Palavras-chave: aeroluminescência, vento neutro, ondas de gravidade, diagrama de bloqueio.
ACOUSTIC TRAVELTIME TOMOGRAPHY FOR CO2 INJECTION MONITORING IN RESERVOIRS
Authors: Pereira Luara Rodrigues , Bassrei Amin 
Published: August 2017

ABSTRACT. When considering with greenhouse effect and global warming, carbon dioxide is the main agent. As the major contributors to the increase in global temperature, large companies and corporations have been encouraged to look for ways to reduce the emission of...Keywords: traveltime tomography, reservoir monitoring, geological storage, CO2 injection. RESUMO. Quando tratamos do efeito estufa e aquecimento global temos como seu principal agente o dióxido de carbono. Por serem grandes contribuintes do aumento da temperatura do planeta, grandes empresas...Palavras-chave: tomografia de tempos de trânsito, monitoramento de reservatórios, armazenamento geológico, injeção de CO2.