bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genome Sequence of the Alcelaphine Gammaherpesvirus 1 Attenuated Laboratory Strain WC11
Authors: Ensser Armin 
Published: November 2017

ABSTRACT
The complete genome sequence of the alcelaphine gammaherpesvirus 1 (AIHV-1) attenuated laboratory strain WC11 was determined from purified virion DNA. The viral light DNA (L-DNA) genome of 127,215 bp is mostly conserved compared to the pathogenic strain C500; however, 3.3 kb is deleted in two regions, affecting 4 of 10 AIHV-1-specific open reading frames.
Draft Genome Sequences of Ciprofloxacin-Resistant Salmonella enterica Strains with Multiple-Antibiotic Resistance, Isolated from Imported Foods
Authors: Khan Ashraf A. , Khajanchi Bijay K. , Khan Sana A. , Elkins Christopher A. , Foley Steven L. 
Published: November 2017

ABSTRACT

We report here the draft genome sequences of 15 ciprofloxacin-resistant
Salmonella enterica
strains with resistance to multiple other antibiotics, including aminoglycosides, β-lactams, sulfonamides, tetracycline, and trimethoprim, isolated from different imported foods. Three strains (NCTR75, NCTR281, and NCTR350) showed a high level of ciprofloxacin resistance compared to that of the other isolates. The whole-genome sequencing data provide a better understanding of the antibiotic resistance mechanisms and virulence properties of these isolates.
Complete Genome Sequences of Three Border Disease Virus Strains of the Same Subgenotype, BDSwiss, Isolated from Sheep, Cattle, and Pigs in Switzerland
Authors: Stalder Hanspeter , Marti Sabrina , Flückiger Franziska , Renevey Nathalie , Hofmann Martin A. , Schweizer Matthias 
Published: November 2017

ABSTRACT
We report here the complete genome sequences of three border disease virus (BDV) strains of the same subgenotype isolated in Switzerland from a sheep, a cow, and a pig, respectively. This is the first report of full-length sequences of a tentatively new subgenotype isolated from three different species of cloven-hoofed farm animals.
Genome Sequence of Foot-and-Mouth Disease Virus of Serotype O Lineage Ind-2001d Isolated from Cattle in Mongolia in 2015
Authors: Nishi Tatsuya , Ulziibat Gerelmaa , Khanui Buyantogtokh , Myagmarsuren Odonchimeg , Morioka Kazuki , Yamakawa Makoto , Fukai Katsuhiko 
Published: November 2017

ABSTRACT
We report the whole-genome sequence of the foot-and-mouth disease virus (FMDV) O/MOG/BU/2-7/2015 isolated in Mongolia in 2015. This virus is closely related to isolates identified in Southeast Asia in 2015 and is classified under the O/ME-SA/Ind-2001d lineage. This is the first detection of an FMDV of this lineage in Mongolia.
Complete Genome Sequence of a Novel Strain of Infectious Bronchitis Virus, Isolated from Chickens in China in 2016
Authors: Li Ting-Ting , Li Jin-Yan , Huang Tao , Ge Xing-Yi 
Published: November 2017

ABSTRACT
An avian infectious bronchitis virus (IBV) was detected from trachea swabs of chickens in Hubei province, China, in 2016. The complete genome of the IBV strain, CK/CH/HB/2016, was characterized and analyzed to better understand IBV epidemiology in China.
Analysis of unsuccessful intubations in neonates using videolaryngoscopy recordings
Authors: O’Shea Joyce E , Loganathan Prakash , Thio Marta , Kamlin C Omar Farouk , Davis Peter G 
Published: November 2017

ObjectivesNeonatal intubation is a difficult skill to learn and teach. If an attempt is unsuccessful, the intubator and instructor often cannot explain why. This study aims to review videolaryngoscopy recordings of unsuccessful intubations and explain the reasons why attempts were not successful.Study designThis is a descriptive study examining videolaryngoscopy recordings obtained from a randomised controlled trial that evaluated if neonatal intubation success rates of inexperienced trainees were superior if they used a videolaryngoscope compared with a laryngoscope. All recorded unsuccessful intubations were included and reviewed independently by two reviewers blinded to study group. Their assessment was correlated with the intubator’s perception as reported in a postintubation questionnaire. The Cormack-Lehane classification system was used for objective assessment of laryngeal view.ResultsRecordings and questionnaires from 45 unsuccessful intubations were included (15 intervention and 30 control). The most common reasons for an unsuccessful attempt were oesophageal intubation and failure to recognise the anatomy. In 36 (80%) of intubations, an intubatable view was achieved but was then either lost, not recognised or there was an apparent inability to correctly direct the endotracheal tube. Suctioning was commonly performed but rarely improved the view.ConclusionsLack of intubation success was most commonly due to failure to recognise midline anatomical structures. Trainees need to be taught to recognise the uvula and epiglottis and use these landmarks to guide intubation. Excessive secretions are rarely a factor in elective and premedicated intubations, and routine suctioning should be discouraged. Better blade design may make it easier to direct the tube through the vocal cords.
Protocol for hospital based-surveillance of cerebral palsy (CP) in Hanoi using the Paediatric Active Enhanced Disease Surveillance mechanism (PAEDS-Vietnam): a study towards developing hospital-based disease surveillance in Vietnam
Authors: Khandaker Gulam , Van Bang Nguyen , Dũng Trịnh Quang , Giang Nguyen Thi Huong , Chau Cao Minh , Van Anh Nguyen Thi , Van Thuong Nguyen , Badawi Nadia , Elliott Elizabeth J 
Published: November 2017

IntroductionThe epidemiology, pathogenesis, management and outcomes of cerebral palsy (CP) in low-income and middle-income countries including Vietnam are unknown because of the lack of mechanisms for standardised collection of data. In this paper, we outline the protocol for developing a hospital-based surveillance system modelled on the Paediatric Active Enhanced Disease Surveillance (PAEDS) system in Australia. Using PAEDS-Vietnam we will define the aetiology, motor function and its severity, associated impairments, and nutritional and rehabilitation status of children with CP in Hanoi, Vietnam. These essential baseline data will inform future health service planning, health professional education and training, and family support.Methods and analysisThis is a hospital-based prospective surveillance of children with CP presenting to the rehabilitation, neurology and general paediatric services at the National Children’s Hospital and St Paul Hospital in Hanoi. We will use active, prospective daily case-finding for all children with CP aged <18 years who are hospitalised or present to outpatient departments. Following parental consent, data will be collected using a modified version of the Australian Cerebral Palsy Register questionnaire. The data collection form has been developed in consultation with local and international experts and translated into Vietnamese. Information collected will include demographics, maternal health and birth history, type and severity of CP, known risk factors for CP, and nutrition, immunisation, education and rehabilitation status.Ethics and disseminationThis study was approved by the Hanoi Medical University Institutional Review Board (decision no 1722) and The University of Sydney Human Research Ethics Committee (approval no 2016/456). Establishment of PAEDS-Vietnam will enable hospital-based surveillance of CP for the first time in Vietnam. It will identify preventable causes of CP, patient needs and service gaps, and facilitate early diagnosis and intervention. Study findings will be disseminated through local and international conferences and peer-reviewed publications.
Association between body mass index and outcomes after percutaneous coronary intervention in multiethnic South East Asian population: a retrospective analysis of the Malaysian National Cardiovascular Disease Database—Percutaneous Coronary Intervention (NCVD-PCI) registry
Authors: Azhari Zaid , Ismail Muhammad Dzafir , Zuhdi Ahmad Syadi Mahmood , Md Sari Norashikin , Zainal Abidin Imran , Wan Ahmad Wan Azman 
Published: November 2017

ObjectiveTo examine the relationship between body mass index (BMI) and outcomes after percutaneous coronary intervention (PCI) in a multiethnic South East Asian population.SettingFifteen participating cardiology centres contributed to the Malaysian National Cardiovascular Disease Database—Percutaneous Coronary Intervention (NCVD-PCI) registry.Participants28 742 patients from the NCVD-PCI registry who had their first PCI between January 2007 and December 2014 were included. Those without their BMI recorded or BMI <11 kg/m2or >70 kg/m2were excluded.Main outcome measuresIn-hospital death, major adverse cardiovascular events (MACEs), vascular complications between different BMI groups were examined. Multivariable-adjusted HRs for 1-year mortality after PCI among the BMI groups were also calculated.ResultsThe patients were divided into four groups; underweight (BMI <18.5 kg/m2), normal BMI (BMI 18.5 to <23 kg/m2), overweight (BMI 23 to <27.5 kg/m2) and obese (BMI ≥27.5 kg/m2). Comparison of their baseline characteristics showed that the obese group was younger, had lower prevalence of smoking but higher prevalence of diabetes, hypertension and dyslipidemia. There was no difference found in terms of in-hospital death, MACE and vascular complications after PCI. Multivariable Cox proportional hazard regression analysis showed that compared with normal BMI group the underweight group had a non-significant difference (HR 1.02, p=0.952), while the overweight group had significantly lower risk of 1-year mortality (HR 0.71, p=0.005). The obese group also showed lower HR but this was non-significant (HR 0.78, p=0.056).ConclusionsUsing Asian-specific BMI cut-off points, the overweight group in our study population was independently associated with lower risk of 1-year mortality after PCI compared with the normal BMI group.
RASA1 and NF1 are Preferentially Co-Mutated and Define A Distinct Genetic Subset of Smoking-Associated Non–Small Cell Lung Carcinomas Sensitive to MEK Inhibition
Authors: Hayashi Takuo , Desmeules Patrice , Smith Roger S. , Drilon Alexander , Somwar Romel , Ladanyi Marc 
Published: November 2017

Abstract
Purpose: Ras-GTPase–activating proteins (RasGAP), notably NF1 and RASA1, mediate negative control of the RAS/MAPK pathway. We evaluated clinical and molecular characteristics of non–small cell lung carcinoma (NSCLC) with RASA1 mutations in comparison with NF1-mutated cases.
Experimental Design: Large genomic datasets of NSCLC [MSK-IMPACT dataset at MSKCC (n = 2,004), TCGA combined lung cancer dataset (n = 1,144)] were analyzed to define concurrent mutations and clinical features of RASA1-mutated NSCLCs. Functional studies were performed using immortalized human bronchial epithelial cells (HBEC) and NSCLC lines with truncating mutations in RASA1, NF1, or both.
Results: Overall, approximately 2% of NSCLCs had RASA1-truncating mutations, and this alteration was statistically, but not completely, mutually exclusive with known activating EGFR (P = 0.02) and KRAS (P = 0.02) mutations. Unexpectedly, RASA1-truncating mutations had a strong tendency to co-occur with NF1-truncating mutations (P &lt; 0.001). Furthermore, all patients (16/16) with concurrent RASA1/NF1-truncating mutations lacked other known lung cancer drivers. Knockdown of RASA1 in HBECs activated signaling downstream of RAS and promoted cell growth. Conversely, restoration of RASA1 expression in RASA1-mutated cells reduced MAPK and PI3K signaling. Although growth of cell lines with inactivation of only one of these two RasGAPs showed moderate and variable sensitivity to inhibitors of MEK or PI3K, cells with concurrent RASA1/NF1 mutations were profoundly more sensitive (IC50: 0.040 μmol/L trametinib). Finally, simultaneous genetic silencing of RASA1 and NF1 sensitized both HBECs and NSCLC cells to MEK inhibition.
Conclusions: Cancer genomic and functional data nominate concurrent RASA1/NF1 loss-of-function mutations as a strong mitogenic driver in NSCLC, which may sensitize to trametinib. Clin Cancer Res; 24(6); 1436–47. ©2017 AACR.
See related commentary by Kitajima and Barbie, p. 1243
Political Economy through the Looking Glass
Authors: Best Beverley 
Published: November 2017

Abstract
Two sets of co-authors, LiPuma and Lee, and Bryan and Rafferty, each argue that contemporary ‘speculative’ or ‘circulatory’ capitalism represents a deep rupture in the modality of capitalist accumulation from earlier forms of industrial capitalism such that the Marxian critique of value-form is now redundant. I argue that despite the altered surface-appearances of financialisation, the essential character of social domination carried out in the process of capitalist production-circulation in financialisation constitutes, rather, a continuation of the particular movement of capital from earlier historical conjunctures. As such, traditional formulations of Marxian categories such as class, exploitation and the value-form remain relevant and, indeed, necessary for the analysis of the mode of social domination in the era of financialisation.
Grammaticalization in Emirati Arabic
Authors: Jarad Najib Ismail 
Published: November 2017

Abstract
This paper is concerned with the process of language change whereby lexical items and constructions, in specific contexts, come to serve new grammatical functions. Emirati Arabic provides us with a wide range of grammaticalization phenomena. The aim of this paper is twofold: to shed light on the basic concepts relating to grammaticalization phenomena and to examine the grammaticalization of a number of constructions in Emirati Arabic, investigating their formation and the changes in their functions. The development of these grammatical constructions follows a grammaticalization pathway identified for a wide range of linguistic items cross-linguistically.
The Feminine Ending -at as a Diptote in the Qurʾānic Consonantal Text and Its Implications for Proto-Arabic and Proto-Semitic
Authors: van Putten Marijn 
Published: November 2017

Abstract
This paper examines the feminine ending -at in the Qurʾānic Consonantal Text. It argues that from the Qurʾānic Consonantal Text, and various data of comparative linguistic evidence, it is likely that the language of the Qurʾānic Consonantal Text goes back to a variety of Arabic where the feminine ending was treated as a diptote. It is moreover argued, that this feminine ending was likely also diptotic in Proto-Arabic.
Two icc Arbitrations Disturbed by Two Court Orders: The Impact of Ignoring the Power of the icc Court to Extend the Time Limit for the Award
Authors: Abu-Hagras Mostafa 
Published: November 2017

Abstract
The 1994 Egyptian Arbitration Act has conferred the jurisdiction to terminate arbitral proceedings, if the time limit for the award expires, on Egypt’s courts. The Egyptian courts have wrongfully terminated two International Chamber of Commerce arbitration proceedings. Egypt’s Court of Cassation has ultimately reversed the decisions of the Egyptian lower courts, so the two icc arbitration awards have survived. This article examines the manner in which the Egyptian courts were asked to grant, recognise or refuse to recognise the termination orders, and clarifies how arbitrators, the icc Court and parties reacted to them.
R. G. Collingwood and the Presence of the Past
Authors: Ahlskog Jonas 
Published: November 2017

Abstract
This essay examines recent theories about the presence of the past from the perspective of Collingwood’s philosophy of history. In the work of Eelco Runia and Frank Ankersmit among others, elaborate theories are offered for explaining how the past conditions and moves the present. Collingwood addresses the same kind of issues in his philosophy of history, but his ideas are very seldom discussed in presence theory. The aim of this essay is to place Collingwood’s philosophy of history in dialogue with presence theory. I show that, even though Collingwood and presence theory have similar aims, Collingwood offers a fundamentally different account of how the past lives on in the here and now. Not only is Collingwood’s account different – his conception of history undermines central presuppositions of presence theory. In conclusion, I argue that Collingwood’s account shows how questions about the presence of the past are intimately connected with self-knowledge.
“Was he right?” R. G. Collingwood’s Rapprochement between Philosophy and History
Authors: Fear Christopher 
Published: November 2017

Abstract
R. G. Collingwood’s declaration that belief in “eternal questions” in philosophy is “merely a vulgar error, consequent on a kind of historical myopia which, deceived by superficial resemblances, failed to detect profound differences” has been vigorously discussed over the last sixty years, thanks partly to its resurrection by Quentin Skinner. But another of Collingwood’s provocative claims has been relatively neglected. If the claims and arguments of classic authors in the history of philosophy provide answers to questions that are not ours, but that are in fact limited to the context of their own time; and if the purpose of history is to illuminate those answers in light of their historical contexts, should historians ask – as Collingwood claimed they “must” – not only “what was So-and-so’s theory on such and such a matter?”, but also “was he right?”? Should the historian of ideas in a world of changing questions nevertheless describe a theory as “false” or “true”, as Collingwood does, or is truth assessment no proper part of the history of philosophy? This essay draws on the full range of Collingwood’s writings, and presents his strongest case for the claim that historians “must” ask “the truth question” about old philosophy.
Staging Ireland’s Dispossessed
Authors: McMullan Anna 
Published: November 2017

This article explores the tension between the growing cultural capital of the Beckett ‘brand’ and the issues of dispossession which are at the heart of Beckett’s work through an investigation of selected productions from the Beckett in the City project, a series of site-specific performances of Beckett’s work directed by Sarah Jane Scaife. The discussion of Dublin performances of Act Without Words II (2013) and Beckett in the City: the Women Speak (2015) in marginalized urban spaces draws on writing by Judith Butler and Athena Athanasiou on dispossession.
Two Types of Physical Inconsistency to Avoid with Univariate Quantile Mapping: A Case Study over North America Concerning Relative Humidity and Its Parent Variables
Authors: Grenier Patrick 
Published: November 2017

AbstractUnivariate quantile mapping (QM), a technique often used to statistically postprocess climate simulations, may generate physical inconsistency. This issue is investigated here by classifying physical inconsistency into two types. Type I refers to the attribution of an impossible value to a single variable, and type II refers to the breaking of a fixed intervariable relationship. Here QM is applied to relative humidity (RH) and its parent variables, namely, temperature, pressure, and specific humidity. Twelve sites representing various climate types across North America are investigated. Time series from an ensemble of ten 3-hourly simulations are postprocessed, with the CFSR reanalysis used as the reference product. For type I, results indicate that direct postprocessing of RH generates supersaturation values (>100%) at relatively small frequencies of occurrence. Generated supersaturation amplitudes exceed observed values in fog and clouds. Supersaturation values are generally more frequent and higher when RH is deduced from postprocessed parent variables. For type II, results show that univariate QM practically always breaks the intervariable thermodynamic relationship. Heuristic proxies are designed for comparing the initial bias with physical inconsistency of type II, and results suggest that QM generates a problem that is arguably lesser than the one it is intended to solve. When physical inconsistency is avoided by capping one humidity variable at its saturation level and deducing the other, statistical equivalence with the reference product remains much improved relative to the initial situation. A recommendation for climate services is to postprocess RH and deduce specific humidity rather than the opposite.
Situation Awareness Performance in Healthy Young Adults Is Associated With a Serotonin Transporter Gene Polymorphism
Authors: González-Giraldo Yeimy , González-Reyes Rodrigo E. , Mueller Shane T. , Piper Brian J. , Adan Ana , Forero Diego A. 
Published: November 2017

Background Situation awareness (SA) is defined in three levels: SA1 is the perception of the elements in a specific context, SA2 is the comprehension of their meaning, and SA3 is the projection of their status. Purpose To analyze the possible association of a genetic polymorphism in the serotonin transporter ( SLC6A4) gene and performance on the Situational Awareness test (SAtest). Methods SAtest was applied to a sample of 230 healthy Colombian subjects, using the Psychology Experiment Building Language platform and a functional polymorphism in the SLC6A4 gene was genotyped by polymerase chain reaction. Results In the SA1 level, s/s genotype carriers had worse accuracy, in comparison with s/l and l/l genotypes. At SA2 level, l/l genotype carriers had better accuracy than s/s and s/l individuals and that in the SA3 level, l/l carriers also had better accuracy. These associations were significant after correction for multiple testing. Conclusions It is possible that l/l carriers have a better ability to perceive and focus their attention on the elements of their environment and to have the capacity to understand and predict what will happen with those elements. This is the first genetic study of SA performance in healthy participants. Additional investigations of other genes could contribute to the understanding of the molecular correlates of SA in healthy subjects and in neuropsychiatric patients.