bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Penggunaan Pati Biji Cempedak (Arthocarpus champeden Lour) sebagai Bahan Pengikat terhadap Sifat Fisik Tablet Parasetamol secara Granulasi Basah
Authors: Sapri Sapri , Setiawan Dedi , Khairunnisa Rizki 
Published: June 2017

The research about influent the use of cempedak seed starch (Arthocarpus champeden Lour) as a binder to the physical properties of paracetamol tablet in wet granulation has been conducted. Cempedak seed starch can improve the quality of materials, increase the viscosity, gelation ability, rehydration ability and increase the solubility. Paracetamol tablet be made in three formulas, with various concentration binders formula FA 6%, FB 8% and FC 10%. The resulting granules and tablets were evaluated. Granule evaluation includes fluiditas test and moisture content. Tablet evaluation includes uniformity of weight test, uniformity of size, hardness test and disintegration test. Granule evaluation results show that all formulas has qualified, except granule formula FA wich contain moisture 1.78%. Tablet evaluation results show that all formulas has qualified FI Ed. IV. Whereas for hardness test, tablet formula FA not eligible because it has hardness 3.8 Kg/cm2. The results of this research indicate that cempedak seed starch can be used as a binder in the manufacture of wet granulation paracetamol tablets. The higher the concentration used cempedak seed starch, than produced a good tablet. Cempedak seed starch can be used as a binder in concentration 8% and 10%.
Key Words : Cempedak seed starch (Arthocarpus champeden Lour.), paracetamol tablet, wet granulation

ABSTRAK
Telah dilakukan penelitian tentang pengaruh penggunaan pati biji cempedak (Arthocarpus champeden Lour.) sebagai bahan pengikat terhadap sifat fisik tablet parasetamol secara granulasi basah. Pati biji cempedak dapat meningkatkan kualitas bahan, berupa naiknya viskositas, kemampuan gelasi, daya rehidrasi dan kemudahan melarut. Tablet parasetamol dibuat tiga formula dengan variasi konsentrasi bahan pengikat formula FA 6%, FB 8% dan FC 10%. Granul dan tablet yang dihasilkan dievaluasi, evaluasi granul meliputi waktu alir granul dan kandungan lembab, evaluasi tablet yang meliputi uji keseragaman bobot, keseragaman ukuran, kekerasan dan waktu hancur. Hasil evaluasi granul menunjukkan bahwa granul yang dihasilkan dari ketiga formula telah memenuhi persyaratan, kecuali granul formula FA yang memiliki kandungan lembab 1,78%. Hasil evaluasi tablet menunjukkan bahwa tablet dari ketiga formula tersebut telah memenuhi persyaratan tablet pada FI Ed. IV. Sedangkan untuk uji kekerasan, tablet formula FA tidak memenuhi persyaratan karena memiliki kekerasan 3,8 Kg/cm2. Hasil penelitian ini menunjukkan bahwa pati biji cempedak dapat digunakan sebagai bahan pengikat dalam pembuatan tablet parasetamol secara granulasi basah. Semakin tinggi konsentrasi pati biji cempedak yang digunakan, maka sifat fisik tablet yang dihasilkan semakin baik. Pati biji cempedak dapat digunakan sebagai bahan pengikat tablet dan memberikan sifat fisik tablet yang baik pada konsentrasi 8% dan 10%.
Kata Kunci: Pati biji cempedak (Arthocarpus champeden Lour.), tablet parasetamol, granulasi basah
Potensi Herba Tumbuhan Balsem (Polygala paniculata Linn) sebagai Sumber Bahan Farmasi Potensial
Authors: Rijai Laode 
Published: June 2017

Tumbuhan balsem (P. paniculata) merupakan tumbuhan semusim yaitu dari biji lalu tumbuh dan akan mati setelah mencapai dewasa selama 4-5 bulan. Tumbuhan ini berbau balsem sehingga dinamakan tumbuhan balsem oleh masyarakat di Kalimantan Timur. Manfaat tradisional tumbuhan ini tidak banyak dikenal kecuali akarnya dipercaya dapat meningkatkan stamina. Belum banyak hasil penelitian ilmiah tumbuhan ini sehingga diperlukan informasi ilmiah untuk pemanfaatannya. Potensi biologi tumbuhan Balsemadalah mudah tumbuh dengan skilus hidup pendek yaitu 4-5 bulan. Beberapa hasil penelitian terhadap tumbuhan balsem terbukti memiliki potensi dalam bidang kefarmasian seperti sitotoksik atau antikanker, antibakteri, dan antimikotik. Potensi herba balsem juga digambarkan melalui kandungan metabolit sekundernya yaitu mengandung alkaloid, flavanoid, tanin, saponin, dan steroid. Keragaman metabolit sekunder tersebut menggambarkan kemungkinan masih memiliki potensi kefarmasian lainnya.
Kata Kunci: Herba Balsem (Polygala paniculata), sumber bahan farmasi potensial.

ABSTRACT
Plant balm (P. paniculata) is an annual plant that grows from the seed and will die after reaching mature for 4-5 months. This plant is so named smelling balm balm plant communities in East Kalimantan. Traditional benefits of this plant is not widely known but its roots are believed to increase stamina. Not many plants is the result of scientific research that is necessary for the utilization of scientific information. Potential biological plant is easy to grow with skilus Balsemadalah short life is 4-5 months. Several studies have proved the balsam plant potential in the field of pharmacy such as cytotoxic or anticancer, antibacterial, and antimycotic. Potential herbal balm is also illustrated through the content of secondary metabolites that contain alkaloids, flavonoids, tannins, saponins, and steroids. Illustrate the diversity of secondary metabolites may still have potential for other pharmacy.
Key Words: Antioxidant, Ageratum conyzoides L., Captosapelta Tomentosa V., Lepisanthes amoena, Acanthus ilicifolius L., DPPH
Uji Toksisitas Akut dan Subakut Pada Pemberian Ekstrak Etanol Bawang Tiwai (Eleutherine Americana Merr.)
Authors: Sastyarina Yurika 
Published: June 2017

The ethanolic extract from the bulb of Eleutherine americana was investigated for acute and subacute toxicity in Balb/C male mice. The parameter used on this research is mortality n hepar histophatological. During acute toxicity study, bulb plant (0.52, 0,26 and 5.2 mg/kg b.wt) p.o. for 72 hour and subacute toxicity study bulb plant (0.52, 0,26 and 5.2 mg/kg b.wt) p.o. once daily for 30 days. The result of the research shows that ethanol extract with 0.52, 0,26 and 5.2 mg/kg b.wt dosage can be said relatively safe because there is no death signal about 50% in 24 hour and the result of subacute toxicity in observation histophatological in hepar shows there is fibrosis n necrosis with 0.52, 2.6 mg/kg b.wt and 5.2 mg/kg b.wt dosage.
Keywords : bulb, Eleutherine americana , acute and subacute toxicity

ABSTRAK
Telah dilakukan penelitian toksisitas subakut pada ekstrak etanol umbi bawang tiwai (Eleutherine americana (Aubl.). Merr) dari mencit jantan. Parameter yang digunakan dalam penelitian ini adalah kematian dan hispatologi hati. Pada uji toksisitas akut diberikan ekstrak etanol bawang tiwai sekali dengan dosis 0,52 mg/kgBB, 2,6 mg/kgBB, dan 5,2 mg/kgBB dan dilakukan pengamatan selama 72 jam sedangkan pada toksisitas subakut dengan pemberian berulang setiap hari sekali selama 30 hari. Hasil penelitian menunjukkan bahwa bahwa ekstrak bawang tiwai dengan dosis 0,52 mg, 2,6 mg, dan 5,2 mg/KgBB dapat dikatakan relatif aman karena selama 24-72 jam tidak menunjukkan kematian hewan uji (mencit) sebanyak 50% dan hasil pengamatan hispatologi hepar menunjukkan bahwa dosis 0,52 mg/20 g bb mencit, 2,6 mg/20 g bb mencit, dan 5,2 mg/20 g bb mencit dapat menyebabkan perubahan histologi hati mencit berupa fibrosis, nekrosis.
Kata Kunci : Umbi, Eleutherine Americana, uji akut dan subakut
Stabilitas Fisik dan Kimia Minyak Biji Ketapang (Terminalia catappa L.) Selama Penyimpanan
Authors: Saputri Delima , Fitriani Victoria Yulita , Masruhim Muhammad Amir 
Published: June 2017

Ketapang (Terminalia catappa L.) is each one potentialy to producting of nabati oil. The research is purposes to determine effect of storage period on room and extreme temperature of ketapang seeds oilâ€™s physical and chemical stability. Ketapang seeds oil was getted from ketapang seeds extraction by n-hexana with soxhletasi method. Ketapang seeds oil stability evaluation on room temperature 27 â€“ 30 Â°C as long as 50 days and extreme temperature 65 Â°C as long as 10 days. Physical stability that color, aroma, and flavor use organolepticly, pH use pH-meter, density use piknometer, and viscosity use Oswald viscometer. Chemical stability that acid value, peroxide value, and soap value by titration method, and amount of tocopherol compound by spectrometry method. The result data was analyzed with linier regretion. The analyzed result of aroma, flavor, pH, density, soap value, and tocopherol compound showed descend linier, viscosity, acid value, and peroxide value showed ascend linier, and color of ketapang seeds oil is stabil as long as storage on room and extreme temperature. Storage period on extreme temperature more significant than room temperature to effect evaluation result of ketapang seeds oilâ€™s physical and chemical parameters.
Key Words: Terminalia catappa L., Storage Period, Physical and Chemical Stability.

Abstrak
Ketapang (Terminalia catappa L.) merupakan salah satu tumbuhan yang berpotensi sebagai penghasil minyak nabati. Penelitian ini bertujuan untuk mengetahui pengaruh lama penyimpanan pada suhu ruang dan ekstrim terhadap stabilitas fisik dan kimia minyak biji ketapang. Minyak biji ketapang diperoleh dari ekstraksi biji ketapang dengan pelarut n-heksana menggunakan metode soxhletasi. Penentuan stabilitas fisik minyak meliputi warna, bau, dan rasa, pH, bobot jenis, dan viskositas. Penentuan stabilitas kimia meliputi penentuan angka asam, angka peroksida, dan angka penyabunan, serta kandungan tokoferol. Hasil pengujian dianalisis menggunakan regresi linier. Berdasarkan hasil analisis, disimpulkan bahwa pada parameter bau, rasa, pH, bobot jenis, angka penyabunan, dan kandungan tokoferol menunjukkan hubungan linier dengan kecenderungan turun, pengujian terhadap parameter viskositas, angka asam, dan angka peroksida menunjukkan hubungan linier dengan kecenderungan naik, sedangkan parameter warna minyak biji ketapang cenderung stabil selama penyimpanan pada suhu ruang maupun suhu ekstrim. Lama penyimpanan pada suhu ekstrim lebih signifikan mempengaruhi hasil pengujian pada parameter fisik dan kimia minyak biji ketapang dibandingkan pada suhu ruang.
Kata Kunci : Terminalia catappa L., Lama Penyimpanan, Stabilitas Fisik dan Kimia.
Penentuan Dosis Efektif Ekstrak Daun Pacar (Lawsonia inermis L.) sebagai Antiinflamasi
Authors: Megawati Selvi , Herman Herman , Masruhim Muhammad Amir 
Published: June 2017

Has been conducted a research of dose determination of effectiveness extract of Lawsonia inermis L. as anti-inflammatory on Rattus norvegicus. The purpose of this research is to gain an in depth understanding of effective dose of Lawsonia inermis L. as anti-inflammatory toward the reduction time of swelling on Rattus norvegicusâ€™ feet .The method which being used was carrageenan induced on Rattus norvegicusâ€™ feet. Rattus norvegicus were devided to 6 (six) group which a group as negative control was given sodium CMC orally, a group as positive control was given Sodium Diclofenac orally, and 4 (four) as test was given extract with 4 doses variation (50mg/kg, 100mg/kg, 150 mg/kg, and 200 mg/kg) orally to each of mice that has pre-conditioned to swell on its foot. The result shows that T-Count is bigger than T-Table with significant standart 0,05 and smaller than T-Table with significant standart 0,01. It proves that there is significant difference between sodium diclofenac and extract of Lawsonia inermis L in 100mg/kgBW. That concludes that extract of Lawsonia inermis L. has anti-inflammatory effect with effective dose as anti-inflammatory in 100mg/kg.
Keywords : Lawsonia inermis L., Anti-inflammatory., Rattus norvegicus.

Abstrak
Telah dilakukan penelitian penentuan dosis efektif ekstrak daun pacar (Lawsonia inermis L.) sebagai antiinflamasi pada tikus putih (Rattus norvegicus). Penelitian ini bertujuan untuk mengetahui dosis ekstrak daun pacar yang efektif sebagai antiinflamasi terhadap waktu penurunan bengkak pada kaki tikus putih. Metode yang digunakan yaitu induksi karagenan pada kaki tikus putih. Tikus putih dikelompokkan menjadi 6 kelompok yaitu kelompok kontrol negatif diberikan natrium CMC, kelompok kontrol positif diberikan natrium diklofenak dan 4 kelompok uji diberikan ekstrak dengan 4 variasi dosis yaitu 50 mg/kg, 100 mg/kg, 150 mg/kg dan 200 mg/kg yang masing-masing diberikan secara oral dan tiap kaki tikus dikondisikan bengkak terlebih dahulu. Hasil penelitian ini membuktikan ekstrak daun pacar memiliki kemampuan sebagai antiinflamasi dengan dosis efektif 100 mg/kgBB.
Kata Kunci: Lawsonia inermis L., Antiinflamasi, Rattus norvegicus.
Análisis de la implementación y resultados del presupuesto participativo en contextos locales:dos casos en Argentina
Authors: Pagani Maria Laura 
Published: June 2017

Se analiza la problemática de la participación ciudadana en contextos locales, a partir del estudio de dos casos de presupuestos participativos en los municipios de Morón y La Plata (2006-2014), Argentina. La estrategia metodológica siguió un diseño cualitativo, que se realizó a partir de entrevistas, observaciones y análisis documental. Se presentan algunas reflexiones en torno a las modalidades de implementación, el rol de los actores intervinientes y las modalidades de participación, analizando los resultados alcanzados desde la propia gestión municipal y en lo social. Asimismo, se aborda el tipo de proyectos que posibilita esta herramienta de participación y sus alcances en la escala local, identificando las características comunes y las diferencias según los casos. A lo largo del trabajo se intentará demostrar cómo las distintas metodologías de implementación y el papel de los actores intervinientes en los presupuestos participativos bajo análisis influyen en los procesos de participación y en los resultados de la política.
ASAS FREIES ERMESSEN DAN ASPEK PERPAJAKAN LEASING MENURUT KEPUTUSAN MENTERI KEUANGAN NO. 1169/KMK.01/1991 TENTANG KEGIATAN SEWA GUNA USAHA (LEASING)
Authors: Syofyan Syofrin 
Published: June 2017

<p><em>This article discusses the government’s role in granting tax incentives in support of the leasing business which in itself already functions as a financing instrument. The author purports to show how the government’s (the state administration’s) freedom in making policy rules based on the principle of freies ermessen is realized in the economic (tax) sector. The policy rules being discussed is the Ministry of Finance’ Decree no. 1169/KMK.01/1991 re. Leasing. </em></p>
DESAIN TATA LETAK SIRKUIT TERPADU DALAM PERSPEKTIF PERBANDINGAN HUKUM INTEREN
Authors: Sudjana Sudjana 
Published: June 2017

<p><em>The author discusses the legal protection of integrated circuit layout design as provided by Law 32/2000 and compares it with how the government regulates and protect other sorts of intellectual property rights (copyright, trademarks, patents, etc.). The purpose of this comparison is to reveal shortcomings as well as the strength of each different regulations. This study reveals that Law 32/2000 as compared to other IPR protections has yet to provide legal protection of inventor’s moral rights, priority rights as well as temporary decision. At the same time, all regulations cannot be fully implemented due to the lack of or insufficient implementing regulations. </em></p>
Comment le corps vient à l’enfant ? Quelques enjeux autour des représentations corporelles au cours du développement
Authors: Boutinaud Jérôme 
Published: June 2017

La rencontre clinique avec le jeune enfant, que son développement soit harmonieux ou marqué par des souffrances diverses, met en tout cas en avant la nécessité impérieuse que ce dernier rencontre à devoir habiter son corps, se l’approprier subjectivement et s’en construire des représentations. Cette idée communément admise par les milieux scientifiques s’intéressant à ce sujet n’est toutefois pas sans poser un nombre important de questions tant sur le plan terminologique que théorique : la référence parfois confuse à des registres théoriques hétérogènes, le télescopage de vocables paraissant similaires mais loin d’être équivalents (tels ceux d’image du corps et de schéma corporel pour ne citer qu’eux), parce qu’ils se font l’écho de la complexité de la problématique abordée, tendent à dérouter chercheurs et cliniciens et appellent à des éclaircissements. L’auteur propose ici une rétrospective non exhaustive autour de plusieurs de ces modèles théoriques (notamment psychanalytiques), afin de tenter de mieux les resituer et les mettre en perspective. Pour ce faire, ces différents éléments seront regroupés sous la forme de plusieurs domaines (schéma corporel, image du corps, moi corporel, enveloppes psychiques...) en gardant comme fil rouge l’idée d’une lecture plurielle de ce qu’on pourrait appeler l’émergence des représentations corporelles. Quelques propositions seront avancées en conclusion afin de prolonger la réflexion autour de ce sujet et ouvrir sur d’autres pistes d’analyse.
Flipped Learning With Simulation in Undergraduate Nursing Education
Authors: Kim HeaRan , Jang YounKyoung 
Published: June 2017

Background:
Flipped learning has proliferated in various educational environments. This study aimed to verify the effects of flipped learning on the academic achievement, teamwork skills, and satisfaction levels of undergraduate nursing students.

Method:
For the flipped learning group, simulation-based education via the flipped learning method was provided, whereas traditional, simulation-based education was provided for the control group. After completion of the program, academic achievement, teamwork skills, and satisfaction levels were assessed and analyzed.

Results:
The flipped learning group received higher scores on academic achievement, teamwork skills, and satisfaction levels than the control group, including the areas of content knowledge and clinical nursing practice competency. In addition, this difference gradually increased between the two groups throughout the trial.

Conclusion:

The results of this study demonstrated the positive, statistically significant effects of the flipped learning method on simulation-based nursing education. [
J Nurs Educ.
2017;56(6):329–336.]
A New Extended Depth of Focus Intraocular Lens Based on Spherical Aberration
Authors: Bellucci Roberto , Curatolo Maria C. 
Published: June 2017

PURPOSE:
To describe a new extended depth of focus intraocular lens (IOL) design offering multifocality by the variation of spherical aberration in the central optical zone.

METHODS:
The new IOL (Mini WELL; SIFI, Catania, Italy) is an aspheric IOL with positive spherical aberration in the central 2-mm zone and negative spherical aberration in the pericentral 1-mm annulus, the amount of which was determined by specific optic calculation. The new IOL design was tested at the optical bench to investigate depth of focus and sensitivity to tilt, decentration, and angle Kappa. Visual acuity simulations were obtained from distance (4 m) to near (0.5 m).

RESULTS:
Modulation transfer function (MTF) for a 3-mm pupil was 0.35 to 0.40 for distance vision and 0.25 to 0.30 for intermediate and near vision. MTF for a 4.5-mm pupil was 0.40 to 0.55 and 0.10 to 0.20, respectively. These values were not influenced by tilt up to ±2.5°, by decentration up to ±0.5 mm, or by angle Kappa up to 9°. Visual acuity simulations indicated good visual acuity up to 2.00 D of pseudoaccommodation.

CONCLUSIONS:
The new IOL with double spherical aberration in the central 3-mm zone offered good MTF over a wide dioptric interval, suggesting good visual acuity between 4 m and 50 cm. This extended depth of focus IOL with no diffractive rings is expected to produce lower unwanted optical phenomena than current multifocal IOLs.

[
J Refract Surg.
2017;33(6):389–394.]
Los studia humanitatis según Alonso de Cartagena
Authors: Gallardo Luis Fernández 
Published: June 2017

Alonso de Cartagena fue el primer autor español que utilizó la expresión studia humanitatis. Lo hizo en tres ocasiones: en carta dirigida al humanista Pier Candido Decembrio (1438), en el Duodenarium (1442), dedicado a Fernán Pérez de Guzmán, y en el Defensorium unitatis christianae (1449), refiriéndose al rey Juan II. Don Alonso no ofrece una definición explícita. No alude a contenidos específicos, aunque se puede identificar una imprecisa relación con la ética, con la traducción de autores griegos y, de modo más vago, con las artes liberales. Apunta más bien a actitudes intelectuales, a la valoración del debate y del coloquio, al ejercicio de la palabra en situación dialógica. Tampoco identifica studia humanitatis con el uso del latín, pues incluye la actividad literaria de su amigo Pérez de Guzmán. El uso que hizo Cartagena de esta expresión constituye un documento de gran interés sobre la difusión del humanismo en Castilla.
Exploring Athletic Training Educators' Development as Teachers
Authors: Payne Ellen K. , Walker Stacy E. , Mazerolle Stephanie M. 
Published: June 2017

Context:
Little research is available on how athletic training educators develop their instructional styles over the course of their careers and what influences their teaching practices. Understanding the development of athletic training educators' teaching practices may help promote effective teaching in athletic training programs and help guide professional development.

Objective:
To gain a better understanding of how athletic trainers develop as educators and how their experiences as an educator influence their teaching.

Design:
Qualitative study.

Setting:
Higher education institutions.

Patients or Other Participants:
We interviewed 11 doctorally trained athletic trainers teaching in undergraduate professional athletic training programs.

Main Outcome Measure(s):
Data were collected through in-depth interviews, and additional artifacts (curricula vitae, syllabi, videotaped teaching lessons) were used to triangulate data collected during the interviews. We used a phenomenological approach to analyze the data and maintained trustworthiness through member checking, data-source triangulation, multiple-analyst triangulation, and peer review.

Results:
Two main themes emerged from the data: (1) role induction through role continuance and (2) teaching for student learning. Participants discussed how their teaching evolved over the course of their careers, how they valued their clinical practice, how they promoted student learning, and how they aimed to challenge students to transfer knowledge learned into clinical practice.

Conclusions:
From the data, we are able to understand that athletic training educators develop their teaching practices through engaging in their role as a teacher. This was an informal, continual process of learning how to be an educator.
Pedunculated Osteochondroma arising from the Medial Aspect of Proximal Femur: A Rare Presentation
Authors: Hamid Fahad B , Somashekarappa T , Jauhari RP , Singh Somdutt , Agarwal Deepanshu 
Published: June 2017

ABSTRACT
Osteochondroma is a benign bony tumor arising as a bony outgrowth covered by a cartilage cap and occurs most commonly in the metaphysis of long bones (proximal tibia, distal femur, proximal humerus) and pelvis. Osteochondroma grows eccentrically instead of centrifugally. This article reports a case of a 24-yearold female, who presented with a painless bony hard irregular swelling over medial aspect of right groin. There was no distal neurovascular deficit. Site, nature, and extent of the lesion were assessed by radiographs and magnetic resonance imaging. Tumor was completely excised and on histopathology, osteochondroma confirmed. No weight bearing was allowed for 1 week. Patient returned to her normal routine activities in 1 month. On regular follow-up, no evidence of recurrence of the lesion was seen.

How to cite this article
Hamid FB, Singh G, Somashekarappa T, Jauhari RP, Singh S, Agarwal D. Pedunculated Osteochondroma arising from the Medial Aspect of Proximal Femur: A Rare Presentation. Int J Adv Integ Med Sci 2017;2(1):44-46.