bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Sputtered Silicon Oxide Electrolyte for High-Performance Thin-Film Transistors
Authors: Ma Xiaochen , Zhang Jiawei , Cai Wensi , Wang Hanbin , Wilson Joshua , Wang Qingpu , Xin Qian , Song Aimin 
Published: April 2017

AbstractLow operating voltages have been long desired for thin-film transistors (TFTs). However, it is still challenging to realise 1-V operation by using conventional dielectrics due to their low gate capacitances and low breakdown voltages. Recently, electric double layers (EDLs) have been regarded as a promising candidate for low-power electronics due to their high capacitance. In this work, we present the first sputtered SiO2 solid-state electrolyte. In order to demonstrate EDL behaviour, a sputtered 200 nm-thick SiO2 electrolyte was incorporated into InGaZnO TFTs as the gate dielectric. The devices exhibited an operating voltage of 1 V, a threshold voltage of 0.06 V, a subthreshold swing of 83 mV dec−1 and an on/off ratio higher than 105. The specific capacitance was 0.45 µF cm−2 at 20 Hz, which is around 26 times higher than the value obtained from thermally oxidised SiO2 films with the same thickness. Analysis of the microstructure and mass density of the sputtered SiO2 films under different deposition conditions indicates that such high capacitance might be attributed to mobile protons donated by atmospheric water. The InGaZnO TFTs with the optimised SiO2 electrolyte also showed good air stability. This work provides a new pathway to the realisation of high-yield low-power electronics.
First Direct Evidence of Pan-African Orogeny Associated with Gondwana Assembly in the Cathaysia Block of Southern China
Authors: Li Longming , Lin Shoufa , Xing Guangfu , Jiang Yang , He Jian 
Published: April 2017

AbstractMetamorphic zircon from a hornblendite in the South China Block (SCB) yield U-Pb age of 533 ± 7 Ma and Hf model ages from 900 to 1200 Ma. Geochemical and isotopic characteristics indicate that primary magma of the hornblendites was probably derived from an enriched asthenospheric mantle source. This Late Neoproterozoic–Cambrian (Pan-African) metamorphic event provides the first direct evidence that the SCB was an integral part of the Gondwana assembly. Combined with available geological data which show that the SCB has great affinity with India or Australia, the Pan-African metamorphic event most likely belongs to the eastern Kuunga orogeny. We propose that the SCB was located at the nexus between India, Antarctica and Australia along the northern margin of East Gondwana, with the Cathaysia Block connecting western Australia whereas the Yangtze Block facing northern India at ca. 533 Ma.
An in-line Mach-Zehnder Interferometer Using Thin-core Fiber for Ammonia Gas Sensing With High Sensitivity
Authors: Huang Xinyue , Li Xueming , Yang Jianchun , Tao Chuanyi , Guo Xiaogang , Bao Hebin , Yin Yanjun , Chen Huifei , Zhu Yuhua 
Published: April 2017

AbstractAmmonia is an important indicator among environmental monitoring parameters. In this work, thin-core fiber Mach-Zehnder interferometer deposited with poly (acrylic acid) (PAA), poly (allyamine hydrochloride) (PAH) and single-walled carbon nanotubes (SWCNTs-COOH) sensing film for the detection of ammonia gas has been presented. The thin-core fiber modal interferometer was made by fusion splicing a small section of thin-core fiber (TCF) between two standard single mode fibers (SMF). A beam propagation method (BPM) is employed for the design of proposed interferometer and numerical simulation. Based on the simulation results, interferometer with a length of 2 cm of thin-core fiber is fabricated and experimentally studied. (PAH/PAA)2 + [PAH/(PAA + SWCNTs-COOH)]8 film is deposited on the outer surface of thin-core fiber via layer-by-layer (LbL) self-assembly technique. The gas sensor coated with (PAH/PAA)2 + [PAH/(PAA + SWCNTs-COOH)]8 film towards NH3 gas exposure at concentrations range from 1 to 960 ppm are analyzed and the sensing capability is demonstrated by optical spectrum analyzer (OSA). Experimental results show that the characteristic wavelength shift has an approximately linear relationship in the range 1–20 ppm, which is in accordance with the numerical simulation. Thus, this paper reveals the potential application of this sensor in monitoring low concentration NH3 gas.
Emergent Momentum-Space Skyrmion Texture on the Surface of Topological Insulators
Authors: Mohanta Narayan , Kampf Arno P. , Kopp Thilo 
Published: April 2017

AbstractThe quantum anomalous Hall effect has been theoretically predicted and experimentally verified in magnetic topological insulators. In addition, the surface states of these materials exhibit a hedgehoglike “spin” texture in momentum space. Here, we apply the previously formulated low-energy model for Bi2Se3, a parent compound for magnetic topological insulators, to a slab geometry in which an exchange field acts only within one of the surface layers. In this sample set up, the hedgehog transforms into a skyrmion texture beyond a critical exchange field. This critical field marks a transition between two topologically distinct phases. The topological phase transition takes place without energy gap closing at the Fermi level and leaves the transverse Hall conductance unchanged and quantized to e2/2h. The momentum-space skyrmion texture persists in a finite field range. It may find its realization in hybrid heterostructures with an interface between a three-dimensional topological insulator and a ferromagnetic insulator.
Search for ferromagnetic order in overdoped copper-oxide superconductors
Authors: Wu J. , Lauter V. , Ambaye H. , He X. , Božović I. 
Published: April 2017

AbstractIn copper-oxides that show high-temperature superconductivity (HTS), the critical temperature (Tc) has a dome-shaped doping dependence. The cause of demise of bothTcand superfluid densitynson the overdoped side is a major puzzle. A recent study of transport and diamagnetism in a large number of overdoped La2−xSrxCuO4(LSCO) films shows that this cannot be accounted for by disorder within the conventional Bardeen-Cooper-Schrieffer theory. This brings to focus an alternative explanation — competition of HTS with ferromagnetic order, fluctuating in superconducting samples and static beyond the superconductor-to-metal transition. Here, we examine this proposal by growing single-crystal LSCO thin films with doping on both sides of the transition by molecular beam epitaxy, and using polarized neutron reflectometry to measure their magnetic moments. In a heavily overdoped, metallic but non-superconducting LSCO (x = 0.35) film, the spin asymmetry of reflectivity shows a very small static magnetic moment (~2 emu/cm3). Less-doped, superconducting LSCO films show no magnetic moment in neutron reflectivity, both above and belowTc. Therefore, the collapse of HTS with overdoping is not caused by competing ferromagnetic order.
Social brains and divides: the interplay between social dominance orientation and the neural sensitivity to hierarchical ranks
Authors: Ligneul Romain , Girard Romuald , Dreher Jean-Claude 
Published: April 2017

AbstractUbiquitous in the animal kingdom, dominance hierarchies emerge through social competition and underlie the control of resources. Confronting the disruptive influence of socioeconomic inequalities, human populations tend to split into groups who legitimize existing dominance hierarchies and groups who condemn them. Here, we hypothesized that variations in the neural sensitivity to dominance ranks partly underpins this ideological split, as measured by the social dominance orientation scale (SDO). Following a competitive task used to induce dominance representations about three opponents (superior, equal and inferior), subjects were passively presented the faces of these opponents while undergoing fMRI. Analyses demonstrated that two key brain regions, the superior temporal sulcus (STS) and anterior dorsolateral prefrontal cortex (aDLPFC) were sensitive to social ranks. Confirming our hypothesis, the sensitivity of the right aDLPFC to social ranks correlated positively with the SDO scale, which is known to predict behaviors and political attitudes associated with the legitimization of dominance hierarchies. This study opens new perspectives for the neurosciences of political orientation and social dominance.
Non-collinear magnetic structure of manganese quadruple perovskite CdMn7O12
Authors: Guo H. , Fernández-Díaz M. T. , Zhou L. , Yin Y. , Long Y. , Komarek A. C. 
Published: April 2017

AbstractWe report on the magnetic structure of CdMn7O12 determined by powder neutron diffraction. We were able to measure the magnetic structure of this Cd containing and highly neutron absorbing material by optimizing the sample geometry and by blending the CdMn7O12 with Aluminum powder. Below its Néel temperature TN1 all magnetic reflections can be indexed by a single commensurate propagation vector k = (0, 0, 1). This is different to the case of CaMn7O12 where the propagation vector is incommensurate and where an in-plane helical magnetic structure has been found. We observe a commensurate non-collinear magnetic structure in CdMn7O12 with in-plane aligned magnetic moments resembling the ones in CaMn7O12. However, the commensurate propagation vector prevents the appearance of a helical magnetic structure in CdMn7O12. Finally, we also observe a third structural phase transition below ~60 K that can be attributed to phase separation.
Functionalized core-shell hydrogel microsprings by anisotropic gelation with bevel-tip capillary
Authors: Yoshida Koki , Onoe Hiroaki 
Published: April 2017

AbstractThis study describes a novel microfluidic-based method for the synthesis of hydrogel microsprings that are capable of encapsulating various functional materials. A continuous flow of alginate pre-gel solution can spontaneously form a hydrogel microspring by anisotropic gelation around the bevel-tip of the capillary. This technique allows fabrication of hydrogel microsprings using only simple capillaries and syringe pumps, while their complex compartmentalization characterized by a laminar flow inside the capillary can contribute to the optimization of the microspring internal structure and functionality. Encapsulation of several functional materials including magnetic-responsive nanoparticles or cell dispersed collagen for tissue scaffold was demonstrated to functionalize the microsprings. Our core-shell hydrogel microsprings have immense potential for application in a number of fields, including biological/chemical microsensors, biocompatible soft robots/microactuators, drug release, self-assembly of 3D structures and tissue engineering.
Polysulfides (H2Sn) produced from the interaction of hydrogen sulfide (H2S) and nitric oxide (NO) activate TRPA1 channels
Authors: Miyamoto Ryo , Koike Shin , Takano Yoko , Shibuya Norihiro , Kimura Yuka , Hanaoka Kenjiro , Urano Yasuteru , Ogasawara Yuki , Kimura Hideo 
Published: April 2017

AbstractHydrogen sulfide (H2S) exerts synergistic effects with another gaseous signaling molecule nitric oxide (NO) on ion channels and vasculature. However, the mechanism of the synergy is not well understood. Here, we show that the interaction between H2S and NO generates polysulfides (H2Sn), which activate transient receptor potential ankyrin 1 (TRPA1) channels. High performance liquid chromatography with tandem mass spectrometry analysis, along with the imaging of intracellular Ca2+ and H2Sn, showed that H2Sn and their effects were abolished by cyanolysis and by reducing substances such as dithiothreitol (DTT), cysteine, and glutathione (GSH). However, the effects of nitroxyl or nitrosopersulfide, other potential products of H2S and NO interaction, are not affected by cyanolysis or reducing substances. This study demonstrates that H2Sn are products of synergy between H2S and NO and provides a new insight into the signaling mechanisms.
Manipulation of local optical properties and structures in molybdenum-disulfide monolayers using electric field-assisted near-field techniques
Authors: Nozaki Junji , Fukumura Musashi , Aoki Takaaki , Maniwa Yutaka , Yomogida Yohei , Yanagi Kazuhiro 
Published: April 2017

AbstractRemarkable optical properties, such as quantum light emission and large optical nonlinearity, have been observed in peculiar local sites of transition metal dichalcogenide monolayers, and the ability to tune such properties is of great importance for their optoelectronic applications. For that purpose, it is crucial to elucidate and tune their local optical properties simultaneously. Here, we develop an electric field-assisted near-field technique. Using this technique we can clarify and tune the local optical properties simultaneously with a spatial resolution of approximately 100 nm due to the electric field from the cantilever. The photoluminescence at local sites in molybdenum-disulfide (MoS2) monolayers is reversibly modulated, and the inhomogeneity of the charge neutral points and quantum yields is suggested. We successfully etch MoS2 crystals and fabricate nanoribbons using near-field techniques in combination with an electric field. This study creates a way to tune the local optical properties and to freely design the structural shapes of atomic monolayers using near-field optics.
Study of the tensile properties of individual multicellular fibres generated by Bacillus subtilis
Authors: Ye Xuan , Zhao Liang , Liang Jiecun , Li Xide , Chen Guo-Qiang 
Published: April 2017

AbstractMulticellular fibres formed by Bacillus subtilis (B. subtilis) are attracting interest because of their potential application as degradable biomaterials. However, mechanical properties of individual fibres remain unknown because of their small dimensions. Herein, a new approach is developed to investigate the tensile properties of individual fibres with an average diameter of 0.7 μm and a length range of 25.7–254.3 μm. Variations in the tensile strengths of fibres are found to be the result of variable interactions among pairs of microbial cells known as septa. Using Weibull weakest-link model to study this mechanical variability, we predict the length effect of the sample. Moreover, the mechanical properties of fibres are found to depend highly on relative humidity (RH), with a brittle–ductile transition occurring around RH = 45%. The elastic modulus is 5.8 GPa in the brittle state, while decreases to 62.2 MPa in the ductile state. The properties of fibres are investigated by using a spring model (RH < 45%) for its elastic behaviour, and the Kelvin–Voigt model (RH > 45%) for the time-dependent response. Loading-unloading experiments and numerical calculations demonstrate that necking instability comes from structural changes (septa) and viscoelasticity dominates the deformation of fibres at high RH.
Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy
Authors: Lu Zhaojing , Hu Xuebin , Liu Fei , Soares Dinesh C. , Liu Xiliang , Yu Shanshan , Gao Meng , Han Shanshan , Qin Yayun , Li Chang , Jiang Tao , Luo Daji , Guo An-Yuan , Tang Zhaohui , Liu Mugen 
Published: April 2017

AbstractMutations in EYS are associated with autosomal recessive retinitis pigmentosa (arRP) and autosomal recessive cone-rod dystrophy (arCRD) however, the function of EYS and the molecular mechanisms of how these mutations cause retinal degeneration are still unclear. Because EYS is absent in mouse and rat, and the structure of the retina differs substantially between humans and Drosophila, we utilised zebrafish as a model organism to study the function of EYS in the retina. We constructed an EYS-knockout zebrafish-line by TALEN technology which showed visual impairment at an early age, while the histological and immunofluorescence assays indicated the presence of progressive retinal degeneration with a cone predominately affected pattern. These phenotypes recapitulate the clinical manifestations of arCRD patients. Furthermore, the EYS−/− zebrafish also showed mislocalisation of certain outer segment proteins (rhodopsin, opn1lw, opn1sw1, GNB3 and PRPH2), and disruption of actin filaments in photoreceptors. Protein mislocalisation may, therefore, disrupt the function of cones and rods in these zebrafish and cause photoreceptor death. Collectively, these results point to a novel role for EYS in maintaining the morphological structure of F-actin and in protein transport, loss of this function might be the trigger for the resultant cellular events that ultimately lead to photoreceptor death.
Möglichkeiten der optischen Kohärenztomografie-Angiografie bei Diagnostik und postoperativer Verlaufskontrolle von Hämangioblastomen bei Von-Hippel-Lindau-Syndrom
Authors: Lang S. , Evers C. , Cakir B. , Ludwig F. , Lange C. , Agostini H. 
Published: April 2017

Zusammenfassung
Hintergrund Die optische Kohärenztomografie-Angiografie (OCTA) bietet die Möglichkeit, die Gefäße am Augenhintergrund nicht invasiv darzustellen. Bei vaskulären Tumoren, wie Hämangioblastomen bei Von-Hippel-Lindau-Syndrom, können damit neue Informationen zur Tumorstruktur und -perfusion sowie zum Therapieerfolg nach Laserbehandlung gewonnen werden.
Patienten Es wurden 10 Augen von 10 Patienten mit retinalen Hämangioblastomen bei Von-Hippel-Lindau-Syndrom eingeschlossen. Das Alter der Patienten lag zwischen 19 und 65 Jahren (Median 44 Jahre).
Ergebnisse Es wurden insgesamt 10 perfundierte und ein fibrosiertes retinales Hämangioblastom mittels OCTA untersucht. Bei prominenten Tumoren konnte lediglich der oberflächliche Blutfluss dargestellt werden. Vier Hämangioblastome wurden aufgrund der Nähe zur Papille nicht behandelt. Sechs peripher gelegene Tumoren wurden mittels Laser koaguliert. Bei 4 dieser Augen zeigte die OCTA direkt postoperativ ein verringertes Flusssignal in den Tumorgefäßen. Nach der Laserkoagulation wurde die Darstellung der Perfusion teilweise blockiert.
Schlussfolgerung Die OCTA ermöglicht neue Ansätze in der prä- und postoperativen Beurteilung von Hämangioblastomen. Sie hat das Potenzial, wichtige Hinweise zur Morphologie, Perfusion und zum Therapieverlauf zu geben. Prospektive Studien mit längerer Verlaufsbeobachtung sind notwendig, um die therapeutische Relevanz der erfassten Befunde zu validieren.
Prenatal loss of father during World War One is predictive of a reduced lifespan in adulthood
Authors: Todd Nicolas , Valleron Alain-Jacques , Bougnères Pierre 
Published: April 2017

Significance
The First World War was a historical experiment for early-life stress. Fathers of hundreds of thousands of children of all ages were killed during the conflict. The Developmental Origins of Health and Disease hypothesis predicts long-term effects of early-life stress. We collected historical data on French orphans born 1914–1916 and their fathers’ military records and compared the orphans’ mortality in adulthood (age 31–99 y) with that of matched nonorphans. We found a strong decrease in lifespan, reflecting increased mortality before age 65 y, in persons whose fathers died before, not after, their birth. These results support the notion that maternal psychological stress in pregnancy decreases adult longevity in offspring.
mzML2ISA & nmrML2ISA: generating enriched ISA-Tab metadata files from metabolomics XML data
Authors: Larralde Martin , Lawson Thomas N , Weber Ralf J M , Moreno Pablo , Haug Kenneth , Rocca-Serra Philippe , Viant Mark R , Steinbeck Christoph , Salek Reza M 
Published: April 2017

Abstract

Summary
Submission to the MetaboLights repository for metabolomics data currently places the burden of reporting instrument and acquisition parameters in ISA-Tab format on users, who have to do it manually, a process that is time consuming and prone to user input error. Since the large majority of these parameters are embedded in instrument raw data files, an opportunity exists to capture this metadata more accurately. Here we report a set of Python packages that can automatically generate ISA-Tab metadata file stubs from raw XML metabolomics data files. The parsing packages are separated into mzML2ISA (encompassing mzML and imzML formats) and nmrML2ISA (nmrML format only). Overall, the use of mzML2ISA & nmrML2ISA reduces the time needed to capture metadata substantially (capturing 90% of metadata on assay and sample levels), is much less prone to user input errors, improves compliance with minimum information reporting guidelines and facilitates more finely grained data exploration and querying of datasets.

Availability and Implementation
mzML2ISA & nmrML2ISA are available under version 3 of the GNU General Public Licence at https://github.com/ISA-tools. Documentation is available from http://2isa.readthedocs.io/en/latest/.

Supplementary information
Supplementary data are available at Bioinformatics online.
Use of AAScatterPlot tool for monitoring the evolution of the hemagglutinin cleavage site in H9 avian influenza viruses
Authors: Lee Donald W , Whittaker Gary R 
Published: April 2017

Abstract

Motivation
Viruses rapidly evolve due to their error-prone genome replication, and identifying which mutations are selected for during evolution is critical for virus surveillance efforts. Here we introduce a scatter plot tool (AAScatterPlot) that easily shows the selection and avoidance of certain protein mutations based on biochemical properties. We demonstrate its utility for monitoring the evolution of H9 avian influenza viruses from China between 2005 and 2015, particularly at the hemagglutinin (HA) proteolytic cleavage site (PCS) that can affect virus activation and pathogenicity.

Results
Given genome sequences, the AAScatterPlot tool compacts into a single plot, information about the hydropathy index, Van der Waals volume, chemical property and occurrence frequency of amino acid residues. The tool also shows the range of residues that could arise from a single point mutation in the genome, which can then be compared against the observed residues to identify mutation constraints. Through this approach, we found that the 2nd position towards the N-terminus side of the HA PCS (P2 position) avoided hydrophobic residues, whereas the P3 position avoided hydrophilic residues.

Availability and Implementation
AAScatterPlot is available at https://github.com/WhittakerLab/AAScatterPlot.

Supplementary information
Supplementary data are available at Bioinformatics online.
Systemic evaluation of cellular reprogramming processes exploiting a novel R-tool: eegc
Authors: Zhou Xiaoyuan , Meng Guofeng , Nardini Christine , Mei Hongkang 
Published: April 2017

Abstract

Motivation
Cells derived by cellular engineering, i.e. differentiation of induced pluripotent stem cells and direct lineage reprogramming, carry a tremendous potential for medical applications and in particular for regenerative therapies. These approaches consist in the definition of lineage-specific experimental protocols that, by manipulation of a limited number of biological cues—niche mimicking factors, (in)activation of transcription factors, to name a few—enforce the final expression of cell-specific (marker) molecules. To date, given the intricate complexity of biological pathways, these approaches still present imperfect reprogramming fidelity, with uncertain consequences on the functional properties of the resulting cells.

Results
We propose a novel tool eegc to evaluate cellular engineering processes, in a systemic rather than marker-based fashion, by integrating transcriptome profiling and functional analysis. Our method clusters genes into categories representing different states of (trans)differentiation and further performs functional and gene regulatory network analyses for each of the categories of the engineered cells, thus offering practical indications on the potential lack of the reprogramming protocol.

Availability and Implementation
eegc R package is released under the GNU General Public License within the Bioconductor project, freely available at https://bioconductor.org/packages/eegc/.

Supplementary information
Supplementary data are available at Bioinformatics online.