bluuebunny/crossref_metadata_2025_split huggingface dataset:
A literatura, a liberdade e a humanização do homem
Authors: Abrahão Thiago Henrique de Camargo , Infante Ulisses 
Published: July 2017

Em virtude da diminuição paulatina do senso histórico dos homens — consciências por isso passíveis, diante da realidade social, a viverem em meio a valores fragmentados que não permitem uma compreensão mais completa e profunda de sua situação no mundo —, haveria, segundo Jean-Paul Sartre, uma função para a literatura, a saber, ser um meio para estimular a percepção da liberdade e da responsabilidade do homem, evidenciando, com isso, o papel humanizador da arte literária, fundada sobre o alicerce de um pensamento filosófico (o existencialismo) que se quer um humanismo. A partir do pensamento sartriano, veremos que as ideias do crítico literário brasileiro Antonio Candido sobre o papel da literatura convergem para os mesmos propósitos, de modo que, de nossa parte, sublinharemos a importância das afirmações teóricas dos dois estudiosos para debatermos a atualidade.
Historia de una impropiedad: el "Dicionário de bolso", de Oswald de Andrade
Authors: Cabezas Laura 
Published: July 2017

El Diccionario de bolsillo, conjunto de entradas escritas por Oswald de Andrade entre los años treinta y cuarenta, despliega una relectura epifánica de la historia que subvierte las jerarquías y los ordenamientos vigentes, desde la opción por una creencia vital y militante que hace posible el acercamiento entre comunismo y cristianismo.
Colonialismo e anticolonialismo em contos angolanos de João Melo
Authors: Mitidieri André Luis , Gehlen Rejane Seitenfuss 
Published: July 2017

A presente análise busca relacionar as obras literárias Imitação de Sartre & Simone de Beauvoir e Filhos da pátria, de autoria do escritor angolano João Melo, com o colonialismo e o anticolonialismo, que são diretamente implicados ao pós-colonialismo. A literatura pós‑colonial reflete sobre a condição periférica e sua relação contextual. Como aspecto colonialista a ser considerado, na primeira das coletâneas de contos referidas, tem-se a dominação masculina e, na segunda, a organização da elite angolana pós‑independência. Como aspecto anticolonialista, tem-se, no primeiro livro, o pensamento de Simone de Beauvoir acerca da condição feminina, através da busca pela emancipação das personagens femininas e, no segundo, as questões da identidade nacional e individual.. O engajamento sartriano, redimensionado sob a perspectiva pós-colonialista, apresenta-se como estratégia antineocolonialista, fazendo frente ao neocolonialismo, representado pela antiutopia contemporânea e pelo formalismo pós-moderno, subvertido pela metalinguagem, pela paródia e pela reversão de suas expectativas de leitura, na contística de Melo.
Bone marrow cell composition and morphology in healthy juvenile female New Zealand White rabbits (Oryctolagus cuniculus)
Authors: Riedel Rebekah M. , de Matos Ricardo , Schaefer Deanna M. W. 
Published: July 2017

Abstract
OBJECTIVE To provide contemporary preliminary guidelines for the morphological evaluation of bone marrow in conjunction with CBC results for healthy juvenile (3- to 6-month-old) female New Zealand White rabbits (Oryctolagus cuniculus).
ANIMALS 22 female New Zealand White rabbits.
PROCEDURES Each rabbit was sedated, and a blood sample (3 mL) was collected from an ear artery for a CBC, after which the rabbit was euthanized. Within 5 minutes after euthanasia, bone marrow samples were obtained from the femur for cytologic and histologic evaluation. Bone marrow specimens for cytologic evaluation were stained with modified Wright stain, and those for histologic evaluation were stained with either H&E or Prussian blue stain.
RESULTS The CBC results were within published reference ranges for all rabbits except 4, each of which had mild leukopenia. Cytologic assessment of bone marrow revealed a median myeloid-to-erythroid ratio of 0.7 and 2.8 megakaryocytes/low-power field (magnification, 100X), and the median percentages of lymphocytes, plasma cells, and macrophages were 11.5%, 0.1%, and 0%, respectively. The myeloid-to-erythroid ratio was not significantly correlated with any CBC variable. On histologic evaluation of bone marrow, the cellularity ranged from 30% to 50%, there were 2.1 to 7.7 megakaryocytes/hpf (magnification, 400X), and no iron stores were visible in H&E or Prussian blue–stained specimens.
CONCLUSIONS AND CLINICAL RELEVANCE Results of the present study provided contemporary preliminary guidelines for the evaluation of bone marrow in healthy laboratory rabbits.
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5
Authors: Harkey Michael A. , Villagran Alexandra M. , Venkataraman Gopalakrishnan M. , Leisenring Wendy M. , Hullar Meredith A. J. , Torok-Storb Beverly J. 
Published: July 2017

Abstract
OBJECTIVE To determine whether specific alleles of candidate genes of the major histocompatibility complex (MHC) and innate immune system were associated with gastric dilatation-volvulus (GDV) in Great Danes.
ANIMALS 42 healthy Great Danes (control group) and 39 Great Danes with ≥ 1 GDV episode.
PROCEDURES Variable regions of the 2 most polymorphic MHC genes (DLA88 and DRB1) were amplified and sequenced from the dogs in each group. Similarly, regions of 3 genes associated with the innate immune system (TLR5, NOD2, and ATG16L1), which have been linked to inflammatory bowel disease, were amplified and sequenced. Alleles were evaluated for associations with GDV, controlling for age and dog family.
RESULTS Specific alleles of genes DLA88, DRB1, and TLR5 were significantly associated with GDV. One allele of each gene had an OR > 2 in the unadjusted univariate analyses and retained a hazard ratio > 2 after controlling for temperament, age, and familial association in the multivariate analysis.
CONCLUSIONS AND CLINICAL RELEVANCE The 3 GDV-associated alleles identified in this study may serve as diagnostic markers for identification of Great Danes at risk for GDV. Additional research is needed to determine whether other dog breeds have the same genetic associations. These findings also provided a new target for research into the etiology of, and potential treatments for, GDV in dogs.
Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats
Authors: Cannon Claire M. , Trembley Janeen H. , Kren Betsy T. , Unger Gretchen M. , O'Sullivan M. Gerard , Cornax Ingrid , Modiano Jaime F. , Ahmed Khalil 
Published: July 2017

Abstract
OBJECTIVE To investigate protein kinase CK2 (CK2) expression in squamous cell carcinoma (SCC) of cats and to examine effects of CK2 downregulation on in vitro apoptosis and viability in SCC.
SAMPLE Biopsy specimens of oral mucosa and testis and blood samples from clinically normal cats, biopsy specimens of oral SCC from cats, and feline SCC (SCCF1) and mammary gland carcinoma (K12) cell lines.
PROCEDURES Immunohistochemical labeling for CK2α was performed on biopsy specimens. Sequences of the CK2α subunit gene and CK2α’ subunit gene in feline blood and feline cancer cell lines were determined by use of PCR and reverse-transcription PCR assays followed by direct Sanger sequencing. Specific small interfering RNAs (siRNAs) were developed for feline CK2α and CK2α'. The SCCF1 cells were treated with siRNA and assessed 72 hours later for CK2α and CK2α’ expression and markers of apoptosis (via western blot analysis) and for viability (via 3-[4,5-dimethylthiazol-2-yl]-5-[3-carboxymethoxyphenyl]-2-[4-sulfophenyl]-2H-tetrazolium assays).
RESULTS CK2α was expressed in all feline oral mucosa samples and 7 of 8 oral SCC samples. Expression of CK2α and CK2α’ was successfully downregulated in SCCF1 cells by use of siRNAs, which resulted in decreased viability and induction of apoptosis.
CONCLUSIONS AND CLINICAL RELEVANCE In this study, CK2 appeared to be a promising therapeutic target for SCCs of cats. A possible treatment strategy for SCCs of cats would be RNA interference that targets CK2.
Effects of the α2-adrenoceptor agonist medetomidine on the distribution and clearance of alfaxalone during coadministration by constant rate infusion in dogs
Authors: Bennett Rachel C. , Salla Kati M. , Raekallio Marja R. , Scheinin Mika , Vainio Outi M. 
Published: July 2017

Abstract
OBJECTIVE To assess the possible impact of medetomidine on concentrations of alfaxalone in plasma, when coadministered as a constant rate infusion (CRI) to dogs, and to determine the possible impact of medetomidine on the cardiopulmonary effects of alfaxalone during CRI.
ANIMALS 8 healthy adult Beagles.
PROCEDURES 3 treatments were administered in a randomized crossover design as follows: 1 = saline (0.9% NaCl) solution injection, followed in 10 minutes by induction of anesthesia with alfaxalone (loading dose, 2.4 mg/kg; CRI, 3.6 mg/kg/h, for 60 minutes); 2 = medetomidine premedication (loading dose, 4.0 μg/kg; CRI, 4.0 μg/kg/h), followed by alfaxalone (as in treatment 1); and, 3 = medetomidine (as in treatment 2) and MK-467 (loading dose, 150 μg/kg; CRI, 120 μg/kg/h), followed by alfaxalone (as in treatment 1). The peripherally acting α2-adrenoceptor antagonist MK-467 was used to distinguish between the peripheral and central effects of medetomidine. Drugs were administered IV via cephalic catheters, and there was a minimum of 14 days between treatments. Cardiopulmonary parameters were measured for 70 minutes, and jugular venous blood samples were collected until 130 minutes after premedication. Drug concentrations in plasma were analyzed with liquid chromatography–tandem mass spectrometry.
RESULTS The characteristic cardiovascular effects of medetomidine, such as bradycardia, hypertension, and reduction in cardiac index, were obtunded by MK-467. The concentrations of alfaxalone in plasma were significantly increased in the presence of medetomidine, indicative of impaired drug distribution and clearance. This was counteracted by MK-467.
CONCLUSIONS AND CLINICAL RELEVANCE The alteration in alfaxalone clearance when coadministered with medetomidine may be attributed to the systemic vasoconstrictive and bradycardic effects of the α2-adrenoceptor agonist. This could be clinically important because the use of α2-adrenoceptor agonists may increase the risk of adverse effects if standard doses of alfaxalone are used.
Effect of lidocaine on inflammation in equine jejunum subjected to manipulation only and remote to intestinal segments subjected to ischemia
Authors: Bauck Anje G. , Grosche Astrid , Morton Alison J. , Graham A. Sarah , Vickroy Thomas W. , Freeman David E. 
Published: July 2017

Abstract
OBJECTIVE To examine effects of continuous rate infusion of lidocaine on transmural neutrophil infiltration in equine intestine subjected to manipulation only and remote to ischemic intestine.
ANIMALS 14 healthy horses.
PROCEDURES Ventral midline celiotomy was performed (time 0). Mild ischemia was induced in segments of jejunum and large colon. A 1-m segment of jejunum was manipulated by massaging the jejunal wall 10 times. Horses received lidocaine (n = 7) or saline (0.9% NaCl) solution (7) throughout anesthesia. Biopsy specimens were collected and used to assess tissue injury, neutrophil influx, cyclooxygenase expression, and hypoxia-inducible factor 1α (HIF-1α) expression at 0, 1, and 4 hours after manipulation and ischemia. Transepithelial resistance (TER) and mannitol flux were measured by use of Ussing chambers.
RESULTS Lidocaine did not consistently decrease neutrophil infiltration in ischemic, manipulated, or control tissues at 4 hours. Lidocaine significantly reduced circular muscle and overall scores for cyclooxygenase-2 expression in manipulated tissues. Manipulated tissues had significantly less HIF-1α expression at 4 hours than did control tissues. Mucosa from manipulated and control segments obtained at 4 hours had lower TER and greater mannitol flux than did control tissues at 0 hours. Lidocaine did not significantly decrease calprotectin expression. Severity of neutrophil infiltration was similar in control, ischemic, and manipulated tissues at 4 hours.
CONCLUSIONS AND CLINICAL RELEVANCE Manipulated jejunum did not have a significantly greater increase in neutrophil infiltration, compared with 4-hour control (nonmanipulated) jejunum remote to sites of manipulation, ischemia, and reperfusion. Lidocaine did not consistently reduce neutrophil infiltration in jejunum.
Effects of storage conditions on results for quantitative and qualitative evaluation of proteins in canine urine
Authors: Théron Marie-Laure , Piane Laetitia , Lucarelli Laetitia , Henrion Rémi , Layssol-Lamour Catherine , Palanché Florence , Concordet Didier , Braun Jean-Pierre D. , Trumel Catherine , Lavoué Rachel 
Published: July 2017

Abstract
OBJECTIVE To investigate effects of storage conditions on the canine urine protein-to-creatinine ratio (UPC) and on SDS–agarose gel electrophoresis (AGE) of urinary proteins.
SAMPLE Urine specimens from 20 proteinuric (UPC > 0.5) and 20 nonproteinuric (UPC ≤ 0.2) dogs.
PROCEDURES UPC and SDS-AGE were performed on urine specimens stored at room temperature (20°C) and 4°C for up to 5 days and at −20° and −80°C for up to 360 days; some specimens were subjected to 3 freeze-thaw cycles. Results were compared with those obtained for fresh urine specimens.
RESULTS UPC was not affected by storage at room temperature or by freezing. A decrease in UPC was observed for specimens from nonproteinuric dogs after 5 days at 4°C (10%) and from both groups after 90 days at −20° and −80°C (≤ 20% and ≤ 15%, respectively). The SDS-AGE profiles revealed no visual changes regardless of duration of storage for specimens stored at room temperature, 4°C, and −80°C, except for 1 profile after 360 days at −80°C. Repeated freeze-thaw cycles did not affect SDS-AGE profiles. Appearance or strengthening of high-molecular-weight bands that could alter interpretation was evident in SDS-AGE profiles after storage at −20°C for ≥ 15 days (31/40 dogs).
CONCLUSIONS AND CLINICAL RELEVANCE Storage of urine at −20° or −80°C for up to 1 year influenced the UPC without affecting clinical interpretation. Storage of urine specimens at −20°C impaired visual analysis of SDS-AGE. When SDS-AGE cannot be performed on fresh or recently refrigerated urine specimens, storage at −80°C is recommended.
Dermatophytosis in animals: an overview
Authors: Ganguly Subha , Sharma Vijay 
Published: July 2017

Dermatophytosis or ringworm is a fungal infection which causes superficial infection on the animal skin. The lesions are circular in nature resembling a rash which become itchy and develop erythema. It remains covered by a scaly scab. Generally the lesions are evident with loss of fur or hair in that portion of the skin. Clinical signs and symptoms starts within 4 – 14 days after exposure. Different regions on the skin may become infected.
Current developments of biomedical porous Ti–Mo alloys
Authors: Li Yong-Hua , Wang Fang , Li Jian-Jun 
Published: July 2017

Abstract
As a biomedical hard tissue implant candidate, porous Ti–Mo alloy has received considerable attention because of its special porous structure, appropriate Young's modulus and compressive strength as well as good corrosion resistance. As a bioactive coating, hydroxyapatite is commonly used to cover the surface of bioinert metallic prostheses due to its excellent biocompatibility, bone-like structure and composition. This article reviews the current developments and the relationships between the fabrication methods, porous structure, mechanical properties, bioactive surface modification and corrosion behavior of porous Ti–Mo alloy used for hard tissue implant application. Furthermore, the future research directions are discussed to optimize the porous structure and improve the properties of porous Ti–Mo alloys.
Time evolution of agglomerate size of semisolid magnesium alloy AZ91D during a real isothermal shearing
Authors: Li Liang , Zheng Mian 
Published: July 2017

Abstract
The present study attempts to discuss the time evolution of the slurry microstructure of semisolid magnesium alloy AZ91D so as to control the forming process more effectively. We calculated the instantaneous shear stress and the time evolution of average agglomerate size of a real isothermal shearing process containing increasing shear rate, holding the maximal shear rate and decreasing shear rate. The calculated results demonstrate that we should adopt as great a maximal shear rate as possible to achieve a finer slurry microstructure and reduce the resulting larger startup shear stress by increasing the time interval required to increase the shear rate to maximum. Moreover, we also should shorten the time interval required to decrease the shear rate to zero as far as possible, so as to weaken agglomeration during decreasing shear rate and achieve a better final slurry microstructure.
Complex Treatment for the Disposal and Utilization of Process Wastewaters of the Pharmaceutical Industry
Authors: Szabados Erika , Jobbágy Andrea , Tóth András József , Mizsey Péter , Tardy Gábor , Pulgarin Cesar , Giannakis Stefanos , Takács Erzsébet , Wojnárovits László , Makó Magdolna , Trócsányi Zénó , Tungler Antal 
Published: July 2017

A complex treatment of process wastewaters (PWW) of the pharmaceutical industry has been elaborated, the objective was their common disposal and utilization. The biodegradability of polluting components is concentration dependent, the mixing of PWWs with domestic wastewater at WWTP is possible, if no toxic and/or non-biodegradable components are present. So the organic content can serve as carbon source in the denitrification step. The characterization and the proper treatment methods of PWWs have been developed. Only 20-30 % of PWWs required pretreatment. The majority can be mixed directly with the domestic wastewater and send to the WWTP. The characterization includes COD, TOC, BOD, AOX, volatile content, toxicity, metal ion content measurements. The pretreatment methods could be: distillation, WO or catalytic WO. After the activated sludge treatment the degradation of emergent pollutants and the disinfection can be performed by UV-Fenton or high energy irradiation. The design of a complex treatment plant attached to a WWTP of 100000 m3/day capacity and its life-cycle analysis to determine the environmental benefits were carried out also.
All-sky Co-moving Recovery Of Nearby Young Members (ACRONYM). II. The β Pictoris Moving Group∗
Authors: Shkolnik Evgenya L. , Allers Katelyn N. , Kraus Adam L. , Liu Michael C. , Flagg Laura 
Published: July 2017

Abstract
We confirm 66 low-mass stellar and brown dwarf systems (K7–M9) plus 19 visual or spectroscopic companions of the β Pictoris moving group (BPMG). Of these, 41 are new discoveries, increasing the known low-mass members by 45%. We also add four objects to the 14 known with masses predicted to be less than

. Our efficient photometric + kinematic selection process identified 104 low-mass candidates, which we observed with ground-based spectroscopy. We collected infrared observations of the latest spectral types (>M5) to search for low-gravity objects. These and all <M5 candidates were observed with high-resolution optical spectrographs to measure the radial velocities and youth indicators, such as lithium absorption and Hα emission, needed to confirm BPMG membership, achieving a 63% confirmation rate. We also compiled the most complete census of BPMG membership, with which we tested the efficiency and false-membership assignments using our selection and confirmation criteria. Using the new census, we assess a group age of 22 ± 6 Myr, consistent with past estimates. With the now–densely sampled lithium depletion boundary, we resolve the broadening of the boundary by either an age spread or astrophysical influences on lithium-burning rates. We find that 69% of the now-known members with AFGKM primaries are M stars, nearing the expected value of 75%. However, the new initial mass function for the BPMG shows a deficit of 0.2–0.3

stars by a factor of ∼2. We expect that the AFGK census of the BPMG is also incomplete, probably due to biases of searches toward the nearest stars.
Deadly Dark Matter Cusps versus Faint and Extended Star Clusters: Eridanus II and Andromeda XXV
Authors: Amorisco Nicola C. 
Published: July 2017

Abstract
The recent detection of two faint and extended star clusters in the central regions of two Local Group dwarf galaxies, Eridanus II and Andromeda XXV, raises the question of whether clusters with such low densities can survive the tidal field of cold dark matter halos with central density cusps. Using both analytic arguments and a suite of collisionless N-body simulations, I show that these clusters are extremely fragile and quickly disrupted in the presence of central cusps

with

. Furthermore, the scenario in which the clusters were originally more massive and sank to the center of the halo requires extreme fine tuning and does not naturally reproduce the observed systems. In turn, these clusters are long lived in cored halos, whose central regions are safe shelters for

. The only viable scenario for hosts that have preserved their primordial cusp to the present time is that the clusters formed at rest at the bottom of the potential, which is easily tested by measurement of the clusters proper velocity within the host. This offers means to readily probe the central density profile of two dwarf galaxies as faint as

and

, in which stellar feedback is unlikely to be effective.
Giant Primeval Magnetic Dipoles
Authors: Thompson Christopher 
Published: July 2017

Abstract
Macroscopic magnetic dipoles are considered cosmic dark matter. Permanent magnetism in relativistic field structures can involve some form of superconductivity, one example being current-carrying string loops (“springs”) with vanishing net tension. We derive the cross-section for free classical dipoles to collide, finding it depends weakly on orientation when mutual precession is rapid. The collision rate of “spring” loops with tension

in galactic halos approaches the measured rate of fast radio bursts (FRBs) if the loops compose most of the dark matter. A large superconducting dipole (LSD) with mass ∼1020 g and size ∼1 mm will form a ∼100 km magnetosphere moving through interstellar plasma. Although hydromagnetic drag is generally weak, it is strong enough to capture some LSDs into long-lived rings orbiting supermassive black holes (SMBHs) that form by the direct collapse of massive gas clouds. Repeated collisions near young SMBHs could dominate the global collision rate, thereby broadening the dipole mass spectrum. Colliding LSDs produce tiny, hot electromagnetic explosions. The accompanying paper shows that these explosions couple effectively to propagating low-frequency electromagnetic modes, with output peaking at 0.01–1 THz. We describe several constraints on, and predictions of, LSDs as cosmic dark matter. The shock formed by an infalling LSD triggers self-sustained thermonuclear burning in a C/O (ONeMg) white dwarf (WD) of mass ≳1 M
⊙ (1.3 M
⊙). The spark is generally located off the center of the WD. The rate of LSD-induced explosions matches the observed rate of Type Ia supernovae.