bluuebunny/crossref_metadata_2025_split huggingface dataset:
Student bibliographies: charting research skills over time
Authors: Lantz Catherine , Insua Glenda Maria , Armstrong Annie R. , Pho Annie 
Published: August 2016

Purpose
The purpose of this study is to compare two bibliography assignments completed after one-shot library instruction to determine which research skills first-year students retain over the course of a semester.

Design/methodology/approach
A rubric was developed for citation analysis of student-annotated bibliographies and final bibliographies. Each assignment was scored on a three-point scale, and four criteria were assessed: the quality of sources used, variety of sources used, quality of annotations (for first assignment only) and citation accuracy.

Findings
Students scored highest on the quality of sources used in both assignments, although there was a statistically significant decline in overall scores from the first assignment to the second. Students had the most difficulty with writing annotations, followed closely by citation accuracy. Students primarily cited journal articles in their annotated bibliographies and reference sources in their final bibliographies. Website use increased notably from one assignment to the other.

Originality/value
This research is unique in its analysis of two separate bibliography assignments completed by first-year students over the course of a semester. It is of interest to librarians teaching one-shot library instruction or any librarian interested in assessing the research skills of first-year students.
High turnover rates of aerobic anoxygenic phototrophs in European freshwater lakes
Authors: Cepáková Zuzana , Hrouzek Pavel , Žišková Eva , Nuyanzina‐Boldareva Ekaterina , Šorf Michal , Kozlíková‐Zapomělová Eliška , Salka Ivette , Grossart Hans‐Peter , Koblížek Michal 
Published: August 2016

SummaryAerobic Anoxygenic Phototrophic (AAP) bacteria are bacteriochlorophyll (BChl) a ‐containing organisms which use light energy to supplement their predominantly heterotrophic metabolism. Here, we investigated mortality and growth rates of AAP bacteria in three different freshwater lakes in Central Europe: the mountain lake Plešné, the oligo‐mesotrophic Lake Stechlin and the forest pond Huntov. The mortality of AAP bacteria was estimated from diel changes of BChl a fluorescence. Net and gross growth rates were calculated from the increases in AAP cell numbers. The gross growth rates of AAP bacteria ranged from 0.38 to 5.6 d−1, with the highest values observed during summer months. Simultaneously, the rapidly growing AAP cells have to cope with an intense grazing pressure by both zooplankton and protists. The presented results document that during the day, gross growth usually surpased mortality. Our results indicate that AAP bacteria utilize light energy under natural conditions to maintain rapid growth rates, which are balanced by a generally intense grazing pressure.
Desulfovibrio vulgaris CbiKP cobaltochelatase: evolution of a haem binding protein orchestrated by the incorporation of two histidine residues
Authors: Lobo Susana A.L. , Videira Marco A.M. , Pacheco Isabel , Wass Mark N. , Warren Martin J. , Teixeira Miguel , Matias Pedro M. , Romão Célia V. , Saraiva Lígia M. 
Published: August 2016

SummaryThe sulfate‐reducing bacteria of the Desulfovibrio genus make three distinct modified tetrapyrroles, haem, sirohaem and adenosylcobamide, where sirohydrochlorin acts as the last common biosynthetic intermediate along the branched tetrapyrrole pathway. Intriguingly, D. vulgaris encodes two sirohydrochlorin chelatases, CbiKP and CbiKC, that insert cobalt/iron into the tetrapyrrole macrocycle but are thought to be distinctly located in the periplasm and cytoplasm respectively. Fusing GFP onto the C‐terminus of CbiKP confirmed that the protein is transported to the periplasm. The structure‐function relationship of CbiKP was studied by constructing eleven site‐directed mutants and determining their chelatase activities, oligomeric status and haem binding abilities. Residues His154 and His216 were identified as essential for metal‐chelation of sirohydrochlorin. The tetrameric form of the protein is stabilized by Arg54 and Glu76, which form hydrogen bonds between two subunits. His96 is responsible for the binding of two haem groups within the main central cavity of the tetramer. Unexpectedly, CbiKP is shown to bind two additional haem groups through interaction with His103. Thus, although still retaining cobaltochelatase activity, the presence of His96 and His103 in CbiKP, which are absent from all other known bacterial cobaltochelatases, has evolved CbiKP a new function as a haem binding protein permitting it to act as a potential haem chaperone or transporter.
How to manipulate landscapes to improve the potential for range expansion
Authors: Hodgson Jenny A. , Wallis David W. , Krishna Ritesh , Cornell Stephen J. 
Published: August 2016

Summary

Climate change is a global threat to species, and their capacity to adapt could be limited by habitat fragmentation. Many initiatives to restore habitats, increase connectivity and/or ensure ‘functioning ecological networks’ are explicitly or implicitly trying to address this threat. However, existing methods of analysing networks mainly treat the landscape as static, and it is difficult to use these to plan restoration.

We use a recent method to approximate the speed of a species’ range expansion through a landscape by an analogy to an electrical circuit, which takes into account both the rates of colonisation between patches and the rates at which occupied habitat produces new emigrants. Based on this, we propose and test two methods that can help to optimise the spatial arrangement of habitat for range expansion.

First, high current flowing through a habitat patch indicates that it should be a priority for conservation, and this can be the basis of an algorithm for iteratively dropping the least valuable patches. Secondly, high power in a link between two patches indicates that it is a bottleneck in the circuit, and this can be the basis of an algorithm for iteratively adding new patches in the most efficient places. We show that these methods perform well for a variety of realistic landscape patterns, assuming known and fixed dispersal ability and source/target locations.

The calculations involved for each parameter set are fast enough to be used as building blocks in a larger optimisation for practical planning of landscapes for multiple species. Thus, we lay the foundation for a new genre of systematic conservation planning, which efficiently proposes restoration as well as minimising loss.
Hoverflies (Diptera: Syrphidae) benefit from a cultivation of the bioenergy crop Silphium perfoliatumL. (Asteraceae) depending on larval feeding type, landscape composition and crop management
Authors: Mueller Anna Lena , Dauber Jens 
Published: August 2016

Abstract

An increasing production of annual bioenergy crops such as maize has led to regional land‐use changes, causing further shortages of already scarce floral resources for pollinators. Diversification of energy crop production with flowering crops is discussed as a mitigation strategy. The perennial Silphium perfoliatum, characterized by a flowering period between July and September, represents a promising candidate crop.
The present study aimed to investigate the management and landscape conditions under which a cultivation of S. perfoliatum could be an effective measure for pollinator conservation. In this context, hoverflies served as suitable indicators as a result of the different feeding behaviours of adults (floral resources) and larvae (mostly zoophagous or microphagous).
We compared abundance and species richness of adult hoverflies in 15 flowering S. perfoliatum fields in Germany with that in neighbouring habitats (maize fields, ditches/brooks and forest edges) and tested whether the landscape composition influenced local abundance and species richness in S. perfoliatum fields depending on larval feeding type.
Only microphagous hoverflies were more abundant in S. perfoliatum fields than in neighbouring habitats, primarily in mid‐September. This might be explained by the different activity periods and adaptations to flower traits of the two hoverfly groups. Although the abundance of zoophagous hoverflies was positively influenced by a higher crop diversity, the abundance and species richness of microphagous hoverflies responded positively to higher proportions of semi‐natural habitats in the surroundings.
Silphium perfoliatum can support certain hoverfly groups when it is harvested late to ensure a flower supply through to September and when semi‐natural habitats are maintained in agricultural landscapes.
Investigation of lactic acid bacterial strains for meat fermentation and the product's antioxidant and angiotensin‐I‐converting‐enzyme inhibitory activities
Authors: Takeda Shiro , Matsufuji Hisashi , Nakade Koji , Takenoyama Shin‐ichi , Ahhmed Abdulatef , Sakata Ryoichi , Kawahara Satoshi , Muguruma Michio 
Published: August 2016

AbstractIn the lactic acid bacteria (LAB) strains screened from our LAB collection, Lactobacillus (L.) sakei strain no. 23 and L. curvatus strain no. 28 degraded meat protein and tolerated salt and nitrite in vitro. Fermented sausages inoculated strains no. 23 and no. 28 showed not only favorable increases in viable LAB counts and reduced pH, but also the degradation of meat protein. The sausages fermented with these strains showed significantly higher antioxidant activity than those without LAB or fermented by each LAB type strain. Angiotensin‐I‐converting‐enzyme (ACE) inhibitory activity was also significantly higher in the sausages fermented with strain no. 23 than in those fermented with the type strain. Higher ACE inhibitory activity was also observed in the sausages fermented with strain no. 28, but did not differ significantly from those with the type strain. An analysis of the proteolysis and degradation products formed by each LAB in sausages suggested that those bioactivities yielded fermentation products such as peptides. Therefore, LAB starters that can adequately ferment meat, such as strains no. 23 and no. 28, should contribute to the production of bioactive compounds in meat products.
In‐vitroantileishmanial potential of peptide drug hirudin
Authors: Khan Hanif , Nadhman Akhtar , Azam Syed Sikander , Anees Mariam , Khan Imran , Ullah Ikram , Sohail Muhammad Farhan , Shahnaz Gul , Yasinzai Masoom 
Published: August 2016

Hirudin is clinically an important drug used for the treatment of cardiac diseases, but has never been elucidated for antileishmanial potential. This study was designed to determine the therapeutic utility of hirudin against leishmaniasis. Binding affinities of 28 potent proteinase inhibitors were screened computationally against leishmanolysin (GP63), out of which hirudin exhibited higher binding affinity withGP63 and good expectedIC50values. Experimentally, hirudin showed most promising activity against promastigote and axenic amastigote forms of leishmanial parasites withIC50values of 0.60 ± 0.36 μg/mL and 0.43 ± 0.23 μg/mL, respectively, in a dose‐ and time‐dependent assay. The cytotoxicity assay revealed no adverse effects on human macrophages withLD50value of 860.11 ± 53.44 μg/mL. Hirudin caused leishmanial cell death mainly by apoptosis and membrane permeability. In spite of the basic knowledge obtained, hirudin mechanism is considerably less prone to the induction of resistance than classical drugs. Collectively, this study fosters further studies for the hirudin as new antileishmania lead with a new mode of action.
Biological effects of compressive forces exerted on particulate bone grafts during socket preservation: animal study
Authors: Delgado‐Ruiz Rafael , Romanos Georgios E. , Alexandre Gerhke Sergio , Gomez‐Moreno Gerardo , Maté‐Sánchez de Val José Eduardo , Calvo‐Guirado José Luis 
Published: August 2016

AbstractObjectivesTo compare different compressive forces exerted on a particulate graft material during socket preservation and their effects on bone regeneration.Material and methodsSix male dogs were used. The second, third, and fourth premolars, and the first molar were extracted bilaterally at the lower jaws. A particulate synthetic biphasic grafting material (60% HA and 40% β‐tricalcium phosphate) was used. Three different standardized compressive forces were applied randomly during the socket preservation. The sample was divided into four experimental groups Test A (10 g), Test B (50 g), Test C (200 g), and Control (empty sockets). Collagen membranes were placed, and primary closure was obtained. Two months after the surgery the animals were sacrificed, and histomorphometric analysis of non‐decalcified samples was performed at the coronal, middle, and apical thirds.ResultsGrafted sockets resulted in higher bony contour (3 ± 0.43 mm2; P < 0.05). The particles penetrated up to the apical third in the group C but not in the other test groups and controls (P < 0.05). The percentage of new bone were higher at the coronal and apical thirds for Controls and group C compared to A and B groups (P < 0.05). The residual graft was higher for group C (53 ± 1.4%), followed by group B (45 ± 3.1%) and group A (35 ± 1.9%; P < 0.05). The percentages of connective tissue were higher at the middle third without differences between groups (P > 0.05).ConclusionsWithin the limitations of this experimental animal study, it might be concluded that grafted sockets compressed with 200 g force will have higher bony contours; higher compressive forces facilitate the penetration of the particulate graft material into the apical area of the socket and results in more bone formation at the coronal, middle, and apical thirds
A stochastic surplus production model in continuous time
Authors: Pedersen Martin W , Berg Casper W 
Published: August 2016

AbstractSurplus production modelling has a long history as a method for managing data‐limited fish stocks. Recent advancements have cast surplus production models as state‐space models that separate random variability of stock dynamics from error in observed indices of biomass. We present a stochastic surplus production model in continuous time (SPiCT), which in addition to stock dynamics also models the dynamics of the fisheries. This enables error in the catch process to be reflected in the uncertainty of estimated model parameters and management quantities. Benefits of the continuous‐time state‐space model formulation include the ability to provide estimates of exploitable biomass and fishing mortality at any point in time from data sampled at arbitrary and possibly irregular intervals. We show in a simulation that the ability to analyse subannual data can increase the effective sample size and improve estimation of reference points relative to discrete‐time analysis of aggregated annual data. Finally, subannual data from five North Sea stocks are analysed with particular focus on using residual analysis to diagnose model insufficiencies and identify necessary model extensions such as robust estimation and incorporation of seasonality. We argue that including all known sources of uncertainty, propagation of that uncertainty to reference points and checking of model assumptions using residuals are critical prerequisites to rigorous fish stock management based on surplus production models.
Thermodynamic entropy generation in the course of the fatigue crack initiation
Authors: Ontiveros V , Amiri M , Kahirdeh A , Modarres M 
Published: August 2016

AbstractEvolution of the thermodynamic entropy generation during fatigue crack initiation life of notched specimens is studied. A set of experimental results of AA7075‐T651 is examined to determine applicability of the thermodynamic entropy generation as an index of fatigue crack initiation. Entropy accumulation is calculated from hysteresis energy and temperature rise. An increasing trend of entropy accumulation with the number of cycle to failure is observed on macroscale measurements. Results also determine that the entropy generations from the samples under the same operating conditions are similar as the crack grows. Scanning electron microscope analysis is performed on the fractured surfaces to observe the fatigue striations, and persistent slip bands are observed employing an optical microscope. A discussion is presented regarding the length scales on which crack initiation occurs and entropy calculation is made.
Nexus of Emotional and Development Geographies
Authors: Clouser Rebecca 
Published: August 2016

AbstractRecently, the nexus of international development and emotion has received increasing attention from diverse sectors. While scholars from postcolonial, post‐structural, and feminist perspectives have long called for increased attention to emotions and the more‐than‐rational, more recent pieces such as the World Bank's World Development Report 2015 on Mind, Society, and Behavior have also taken up the refrain that “emotions matter” in development. Whether viewed as motivating factors, explanatory devices, or phenomena to be harnessed and manipulated, emotions are emerging as a key piece in development theory and practice. This paper critically analyzes the ways in which the nexus of emotion and development has been conceptualized from various perspectives. In particular, it raises questions related to geographies of power and control and highlights the implications of this emotional turn for both the theory and practice of development.
CRMP1 and CRMP2 have synergistic but distinct roles in dendritic development
Authors: Makihara Hiroko , Nakai Shiori , Ohkubo Wataru , Yamashita Naoya , Nakamura Fumio , Kiyonari Hiroshi , Shioi Go , Jitsuki‐Takahashi Aoi , Nakamura Haruko , Tanaka Fumiaki , Akase Tomoko , Kolattukudy Pappachan , Goshima Yoshio 
Published: August 2016

Collapsin response mediator protein 2, CRMP2, has been identified as an intracellular signaling mediator for Semaphorin 3A (Sema3A). CRMP2 plays a key role in axon guidance, dendritic morphogenesis, and cell polarization. It has been also implicated in a variety of neurological and psychiatric disorders. However, the in vivo functions of CRMP2 remain unknown. We generated CRMP2 gene‐deficient (crmp2−/−) mice. The crmp2−/− mice showed irregular development of dendritic spines in cortical neurons. The density of dendritic spines was reduced in the cortical layer V pyramidal neurons of crmp2−/− mice as well as in those of sema3A−/− and crmp1−/− mice. However, no abnormality was found in dendritic patterning in crmp2−/− compared to wild‐type (WT) neurons. The level of CRMP1 was increased in crmp2−/−, but the level of CRMP2 was not altered in crmp1−/− compared to WT cortical brain lysates. Dendritic spine density and branching were reduced in double‐heterozygous sema3A+/−;crmp2+/− and sema3A+/−;crmp1+/− mice. The phenotypic defects had no genetic interaction between crmp1 and crmp2. These findings suggest that both CRMP1 and CRMP2 mediate Sema3A signaling to regulate dendritic spine maturation and patterning, but through overlapping and distinct signaling pathways.
Efficacy and safety of point‐of‐care ultrasound‐guided intra‐articular corticosteroid joint injections in patients with haemophilic arthropathy
Authors: Martin E. J. , Cooke E. J. , Ceponis A. , Barnes R. F. W. , Moran C. M. , Holle S. , Hughes T. H. , Moore R. E. , von Drygalski A. 
Published: August 2016

Introduction and ObjectivesIntra‐articular corticosteroid injections are standard of care for managing joint pain secondary to osteoarthritis or rheumatoid arthritis but are rarely used in haemophilic arthropathy. We have introduced and evaluated the efficacy and safety of ultrasound‐guided corticosteroid injections for pain relief in patients with haemophilic arthropathy.Patients and methodsUltrasound‐guided intra‐articular injections performed on haemophilia patients at UCSD between March 2012 and January 2016 were analysed. Needle placement and injection (40 mg triamcinolone; 3–5 mL lidocaine) were performed with musculoskeletal ultrasound and Power Doppler. Analysis included patient demographics, joint‐specific parameters such as tissue hypervascularity and effusions, pain relief, and procedure‐associated complications.ResultsForty‐five injections (14 ankles, 13 elbows, 18 knees) were administered in 25 patients. Advanced arthropathy with hypervascularity and/or effusions was present in 91% and 61% of joints, respectively. Ninety‐one per cent of injections resulted in pain relief which was significant in 84% (>30% reduction). Median pain score was reduced from 7 of 10 to 1 of 10 (P < 0.001), usually within 24 h. Median duration of pain relief was 8 weeks (range 1–16 weeks). Haemophilia B patients experienced longer periods of relief, and high Pettersson scores were associated with shorter duration of relief. There were no procedure‐associated complications. Repeat ultrasound of eight joints within 4 weeks of injection demonstrated nearly complete resolution of hypervascularity.ConclusionsPoint‐of‐care ultrasound enabled intra‐articular corticosteroid injections that provided highly effective, safe, and relatively long‐lasting pain relief in haemophilic arthropathy. This approach should be used to improve pain management in haemophilic arthropathy.
Hepatocellular carcinoma developed in a living donor after left lobe donation: a case for caution
Authors: Ikegami Toru , Yoshizumi Tomoharu , Kawasaki Junji , Shimagaki Tomonari , Uchiyama Hideaki , Soejima Yuji , Maehara Yoshihiko 
Published: August 2016

Although it has been recognized that those who are positive for anti‐hepatitis B core antibody (anti‐HBcAb) and negative for hepatitis B surface antigen (HBsAg) with normal liver function could be donors for living donor liver transplantation under appropriate prophylaxis, the negative impact of positive HBcAb on such donors themselves has not been reported. We present a case of a living donor with positive HBcAb, who donated his left lobe for his sister with unresectable giant hepatic hemangioma, and the donor himself developed a de novo hepatocellular carcinoma (HCC) 10 years after donation. He had been lost from the follow‐up program since 1 year after donation. Imaging studies showed a heterogeneously enhanced mass compatible with HCC, which was 9 cm in size with portal invasion into the anterior portal vein of the remnant liver. Re‐laparotomy for hepatectomy with the removal of the tumor thrombus in the anterior portal vein of the remnant liver was carried out, and he is free from recurrence 6 months after surgery on prophylactic sorafenib. At our institute, 58 (9.6%) donors among the 603 living donors were anti‐HBcAb positive and anti‐HBsAg negative, and we started regular HCC surveillance using sonogram every 6 months for these patients.
New Initiation of Long‐Acting Opioids in Long‐Stay Nursing Home Residents
Authors: Pimentel Camilla B. , Gurwitz Jerry H. , Tjia Jennifer , Hume Anne L. , Lapane Kate L. 
Published: August 2016

ObjectivesTo estimate the prevalence of new initiation of long‐acting opioids since introduction of national efforts to increase prescriber and public awareness on safe use of transdermal fentanyl patches.DesignCross‐sectional.SettingU.S. nursing homes (NHs).ParticipantsMedicare‐enrolled long‐stay NH residents (N = 22,253).MeasurementsMinimum Data Set 3.0 was linked with Medicare enrollment, hospital claims, and prescription drug transaction data (January–December 2011) and used to determine the prevalence of new initiation of a long‐acting opioid prescribed to residents in NHs.ResultsOf NH residents prescribed a long‐acting opioid within 30 days of NH admission (n = 12,278), 9.4% (95% confidence interval = 8.9–9.9%) lacked a prescription drug claim for a short‐acting opioid in the previous 60 days. The most common initial prescriptions of long‐acting opioids were fentanyl patch (51.9% of opioid‐naïve NH residents), morphine sulfate (28.1%), and oxycodone (17.2%).ConclusionNew initiation of long‐acting opioids—especially fentanyl patches, which have been the subject of safety communications—persists in NHs.