bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimizing Local Control in High-Grade Uterine Sarcoma: Adjuvant Vaginal Vault Brachytherapy as Part of a Multimodal Treatment
Authors: Annede Pierre , Gouy Sébastien , Mazeron Renaud , Bentivegna Enrica , Maroun Pierre , Petit Claire , Dumas Isabelle , Leary Alexandra , Genestie Catherine , Lhommé Catherine , Deutsch Eric , Morice Philippe , Pautier Patricia , Haie-Meder Christine , Chargari Cyrus 
Published: February 2017

Abstract

Purpose
The phase III European Organization for Research and Treatment of Cancer 55874 study has shown that external beam radiotherapy (EBRT) given as adjuvant treatment decreased locoregional recurrences from 40% to 20% in patients (pts) with localized uterine sarcomas (US). No data exist, however, on the place of brachytherapy (BT).

Material and Methods
We conducted a single-center retrospective analysis of pts receiving adjuvant BT of the vaginal vault based on the vaginal mold technique as part of their multimodal adjuvant treatment for a high-grade US from 1985 to 2015. Treatment characteristics, patterns of relapse, and toxicity were examined.

Results
Median follow-up time was 5.5 years. A total of 98 pts with high-grade US were identified: 81 leiomyosarcomas and 17 undifferentiated sarcomas. Postoperative chemotherapy was delivered in 53 pts. Median dose of EBRT was 45 Gy in 25 fractions. High-dose rate, low-dose rate, and pulsed-dose rate techniques were used in 66, 31, and 1 pts, respectively. At last follow-up, six pts (6.1%) experienced a locoregional relapse as first event. The International Federation of Gynecology and Obstetrics stage and the tumor size were associated with a higher probability of local relapse. When focusing on pts with stage I-III disease, 5-year overall survival was 77% (95% confidence interval: 67%–87%) and 5-year survival without locoregional failure was 91% (83%–98%). Toxicities were mild to moderate, with only four acute grade 3 toxicities and two grade 3 late effects.

Conclusion
Vaginal vault BT as part of a multimodal adjuvant treatment was associated with a high locoregional control rate and with acceptable side effects in localized high-grade US.
Mini incision appendectomy: an analysis of 70 cases
Authors: B. S. Sundaravadanan , P. B. Sudarshan , S. Prabu Shankar 
Published: February 2017

Background: Appendicitis is a common surgical emergency world over, requiring surgical intervention immediately or as elective procedure to avoid complications. Various methods of appendisectomy are in practice, which includes conventional and laparoscopic appendectomy. One other method of appendectomy called mini appendisectomy is performed in selected patients. This study analyses the advantage, feasibility and utility of using mini incision Appendectomy for patients with appendicitis at Saveetha Medical College and Hospital, a teaching tertiary care hospital, Chennai, India.Methods: A total number of 70 cases diagnosed with appendicitis underwent this technique of mini incision appendisectomy mostly under spinal anesthesia. The study period was from 2013 to 2016, for 4 years duration. Patients detailed history, physical examination, operative details, post-operative complications, length of hospital stay, pain scores, analgesic requirements and patient satisfaction scores were collected.Results: Mini-incision appendectomy was performed in 70 patients with 2 cases (2.8%) which required an extension of the incision to 3.5 cm. Wound infection occurred in 2 patients which was treated conservatively. The average operating time was 25 minutes (20-45 minutes). No post-operative mortality. Patients had minimal post-operative pain.Conclusions: Hence mini incision appendectomy is a safe and advantageous technique in performing appendectomy in all hospitals.
Co-authorship networks and institutional collaboration in works about Learning, Teaching and Education Leadership
Authors: Haba Julia , Haba Clara , Osca-Lluch Julia 
Published: February 2017

Bibliometric indicators, based on the statistical analysis of quantitative data from scientific literature, constitute currently in an essential tool for the study of research activity. In the last years, the use of bibliometric indicators as a complement to other scientific indicators to analyse the research situation of a country, its evolution in its time and their position in the international context, has been extended. Collaboration is a characteristic feature of modern science and it is very difficult to measure this aspect. Nevertheless, it is widely accepted to count the combined signatures done by two or more authors, with the analysis of the institutional affiliation mentions and geographical provenance of these authors, constitute a very reasonable and coherent way to estimate this collaboration. To know roughly the peculiarities of patterns of institutional collaboration of researchers working on issues of Learning, Teaching and Education Leadership, we have analysed the institutions where these researchers have worked. Two types of collaboration have been distinguished: national collaboration (between institutions from the same country) and international (between institutions from different countries), using as source of information the communications submitted at the World Conference on Learning, Teaching and Education Leadership (WCLTA) included in the database Web of Science (WoS). The programs used to build collaborative networks were Pajek and Ucinet.A remarkable characteristic is that even if 73% of the works done by co-authorship (done by 2 or more authors), only in 6.19% there was an institutional collaboration. Works done by institutional collaboration move from a range of 52 papers done by institutions in two different countries up to 4 works done by institutions from four countries. The countries with a higher rate of national collaboration are Turkey, Spain, Romania, Czech Republic and Peopleâ€™s R. China. Only 0.80% of the works were made in international institutional collaboration by researchers working in 14 different countries. Of all these country, Turkey, Spain, Italy and Portugal standout being the countries that have participated in a larger number of works carried out with researchers and institutions from other countries.
Key works: institutional collaboration, Learning, Teaching and Education Leadership, Collaboration networks, scientific production
The gonad growth of Anguilla bicolor bicolor induced by hormone combination of HCG, MT, E2, and antidopamine
Authors: Zahri Abdul , Sudrajat Agus Oman , Junior Muhammad Zairin 
Published: February 2017

ABSTRACT The aim of the study was to stimulate eel gonad growth by intramuscularly injection with a hormonal combination of human chorionic gonadotropin (hCG), methyltestosterone (T), estradiol (E2) and antidopamine (A) meanwhile 0.9% NaCl solution was used as control. Estradiol concentration in the blood serum were measured by enzyme-linked immunosorbent assay (ELISA). Stimulation with hCG 20 IU/kg in combination with MT 3 mg/kg and 10 μg/kg antidopamine (hTA treatment) very effective for increased the growth of gonads with indicators gonadosomatic index (GSI) of 4.80%, hepatosomatic index 1.01% and concentration of E2 2.49±0.67 ng/mL were significantly different (P<0.05) than others treatment after ten weeks of application. Key words: hormone, gonad growth, maturation, Indonesian short finned eel ABSTRAK Penelitian ini bertujuan untuk mengetahui pertumbuhan gonad yang distimulasi oleh kombinasi human chorionic gonadotropin (hCG), metiltestosteron (MT), estradiol (E2) dan antidopamin (A). Ikan sidat disuntik dengan hormon dan 0,9% NaCl sebagai kontrol secara intramuskular. Pengukuran konsentrasi hormon E2 dalam serum darah dengan enzyme-linked immunosorbent assay (ELISA). Stimulasi dengan hCG 20 IU/kg dikombinasi dengan MT 3 mg/kg dan antidopamin 10 μg/kg (perlakuan hTA) sangat efektif untuk feminisasi dan meningkatkan pertumbuhan gonad dengan indikator indeks gonadosomatik (GSI) 4,80%, indeks hepatosomatik 1,01% dan konsentrasi E2 2,49±0,67 ng/mL, secara signifikan berbeda pada taraf P<0,05 dibandingkan perlakuan lain setelah sepuluh minggu aplikasi. Kata kunci: hormon, pertumbuhan gonad, maturasi, sidat
Penentuan pH optimum untuk pertumbuhan kepiting bakau Scylla serrata dalam wadah terkontrol
Authors: Hastuti Yuni Puji , Nadeak Horas , Affandi Ridwan , Faturrohman Kurnia 
Published: February 2017

ABSTRACT One of the abiotic factors that affects the growth and the survival of crabs is pH. The optimum pH media will give maximum impact on mangrove crabs because it is related with the osmoregulation process. This study aimed to examine the effect of pH on the survival rate (SR) and specific growth rate (SGR) of mangrove crab Scylla serrata through the reaction of physiological condition. This study consisted of the treatments with the pH medium 5 (A), pH medium 6 (B), pH medium 7 (C), and pH medium 8 (D). The crab’s maintenance in different pH gave a significant effect (P<0.05) on the survival rate of the crabs. The pH treatments also gave a significant effect (P<0.05) on the SGR of the crabs. The low level of crab stress at pH 7 was described by the total value of high hemocyte and the high osmotic load so that the pH 7 was the optimum condition for the crabs. Keywords: pH, survival, specific growth rate, mangrove crabs ABSTRAK Salah satu faktor abiotik yang mempengaruhi pertumbuhan dan kelangsungan hidup kepiting adalah pH. Media pH optimum akan memberikan dampak maksimum pada kepiting bakau karena terkait dengan proses osmoregulasi. Penelitian ini bertujuan untuk menguji pengaruh pH pada tingkat kelangsungan hidup (SR) dan laju pertumbuhan spesifik (SGR) kepiting mangrove Scylla serrata melalui reaksi kondisi fisiologis. Penelitian ini terdiri atas perlakuan dengan media pH 5 (A), sedang pH 6 (B), sedang pH 7 (C), dan menengah pH 8 (D). Pemeliharaan kepiting di pH yang berbeda memberikan pengaruh yang signifikan (P<0,05) pada tingkat kelangsungan hidup kepiting. Perlakuan pH juga memberikan efek yang signifikan (P<0,05) pada SGR dari kepiting. Rendahnya tingkat stres kepiting pada pH 7 digambarkan oleh nilai total hemosit tinggi dan beban osmotik tinggi sehingga pH 7 adalah kondisi optimum untuk kepiting. Kata kunci: pH, kelangsungan hidup, laju pertumbuhan spesifik, kepiting mangrove
Penentuan bobot kayu apu Pistia stratiotes L. sebagai fitoremediator dalam pendederan ikan gurami Lac. ukuran 3 cm
Authors: Nirmala Kukuh , Wardani Sulistia , Hastuti Yuni Puji , Nurusallam Wildan 
Published: February 2017

ABSTRACT The use of high stocking density in nursery causes a decrease of water quality. Technology that can be used to solvethe low water quality in nursery of giant goramy was phytoremediation using Pistia stratiotes L. Purpose of this research was to determine the best weight ratio between P. stratiotes L. and 33 L water in nursery giant goramy size 3 cm. Giant goramy size 3 cm was maintained in an aquarium and was treated with different weight of P. stratiotes L. consisted of 45 g, 90 g, 135 g, and controls P. stratiotes L. 0 g. Cleaning and water change was done once a week. This research showed that the treatment of P. startiotes L. 45g/33 L water gave the best result in survival rate, absolute length of the growth, specific growth rate, feed efficiency and economically profitable. Keywords: phytoremediation, water lettuce, Osphronemus goramy L., nursery ABSTRAK Penggunaan padat tebar tinggi pada pendederan ikan gurami mengakibatkan kualitas air menjadi buruk. Salah satu teknologi yang bisa digunakan untuk mengatasi kualitas air yang buruk pada pendederan ikan gurami adalah fitoremediasi menggunakan tanaman kayu apu. Tujuan penelitian ini adalah menentukan bobot kayu apu dengan volume air 33 L pada pendederan ikan gurami ukuran 3 cm. Ikan gurami ukuran 3 cm dipelihara di dalam akuarium dan diberi perlakuan bobot tanaman kayu apu berbeda yaitu 45 g, 90 g, dan 135 g, serta kontrol (kayu apu 0 g). Penyiponan dan pergantian air dilakukan setiap satu minggu sekali. Hasil penelitian menunjukkan bahwa perlakuan kayu apu 45 g/33 L air menunjukkan hasil tingkat kelangsungan hidup, pertumbuhan panjang mutlak, laju pertumbuhan bobot harian, efisiensi pakan yang paling baik, serta lebih menguntungkan dibandingkan dengan perlakuan kontrol (kayu apu 0 g). Kata kunci: fitoremediasi, kayu apu, Oshpronemus goramy L., pendederan
Aspek biologi reproduksi ikan pari blentik Neotrygon kuhlii di perairan Selat Sunda
Authors: Abubakar Salma , Boer Mennofatria , Sulistiono , 
Published: February 2017

ABSTRACT Bluespotted stingray fish Neotrygon kuhlii is the important fish economically captured from Sunda Strait. Intensive fishing could decrease bluespotted stingray stock. This study was aimed to know the length-weight, and reproduction characteristic. The reproduction characteristic covered the size of first gonad maturity, the level and also index of gonad maturity of bluespotted stingray fish in Labuan Fishing Dock, Banten. The result showed the equilibrium of length-weight of female fish was about W=0.0007L2,1496. Meanwhile, the male fish was about W=0.0000L2.251. Male fish was better than female fish according their relatively condition factor. Decreasing of the factor condition was caused by feeding habit to grow the reproduction cells. The size of first gonad maturity for the female and male respectively were about 550–799 dan 550–760 mm. The highest level maturity even female or male was on IV achieved in June and Juli 2013. Increasing the index (IKG) was followed by the level of gonad maturity. Kata kunci: bluespotted stingray, reproductive characteristic, condition factor, Sunda Strait ABSTRAK Ikan pari blentik Neotrygon kuhlii merupakan salah satu sumberdaya ikan ekonomis penting dan sebagai hasil penangkapan di Selat Sunda. Penangkapan yang intensif dapat mengakibatkan penurunan stok ikan pari blentik. Penelitian ini bertujuan untuk mengetahui panjang bobot, dan karakteristik reproduksi. Karaktersitik reproduksi itu sendiri meliputi ukaran pertama kali matang gonad, tingkat kematangan gonad dan indeks kematangan gonad ikan pari blentik di perairan Selat Sunda yang didaratkan di Pelabuhan Perikanan Pantai (PPP) Labuan, Banten. Berdasarkan hubungan panjang bobot ikan pari betina diperoleh persamaan hubungan panjang dan bobot untuk ikan pari blentik betina W=0,0007L2,1496. Sementara itu pada ikan jantan, persamaan hubungan panjang bobot W=0,0000L2,251. Ikan pari blentik jantan mempunyai faktor kondisi yang relatif lebih besar daripada ikan pari betina. Penurunan nilai faktor kondisi disebabkan bagian terbesar dari makanan yang dikonsumsi digunakan untuk perkembangan sel-sel reproduksinya. Kisaran ukuran pertama kali matang gonad ikan pari blentik betina 550–799, sedangkan untuk ikan pari jantan adalah dengan kisaran panjang total tubuh 550–760 mm. Tingkat kematangan gonad tertinggi ikan betina dan jantan (TKG IV) ditemukan pada bulan Juni dan Juli 2013. Indeks kematangan gonad (IKG) ikan pari semakin meningkat seiring dengan meningkatnya TKG. Keywords: ikan pari blentik, karakteristik reproduksi, faktor kondisi, Selat Sunda
La volatilidad del tipo de cambio paralelo en Venezuela 2005-2015
Authors: Castillo Paredes Laura Daniela , Ramoni Perazzi Josefa 
Published: February 2017

El tipo de cambio paralelo constituye una de las principales variables económicas para la toma de decisiones en Venezuela. Para analizar el comportamiento de esta variable tomando en cuenta sus características inherentes, exceso de curtosis, persistencia y asimetría, se hace una síntesis teórica de los principales modelos estocásticos de volatilidad y, se estima un conjunto de modelos. El modelo que mejor ajusta el comportamiento de la variable es un EGARCH (1,1), que captura el efecto asimétrico de las perturbaciones estocásticas sobre la serie. Ante choques negativos (depreciación del tipo de cambio paralelo), la volatilidad asociada se incrementa, pero para choques positivos (apreciación del tipo de cambio paralelo), se mantiene constante.
1910 Colombian constitutional reform and the electoral system (1910-1914)
Authors: Acuña Rodríguez Olga Yanet 
Published: February 2017

In 1910 in Colombia a constitutional reform took place. It was promulgated through Legislative Act 03 and its aim was to strengthen the development of democracy, as a strategy for mediating the bipartisan conflict that Colombian society had been living through since the XIX century. Therefore, governments needed to be legitimated periodically and systematically through the ballot box. Although the elections were not enough to define a democratic political system, they were associated with the expression of representative democracy. The objective of this work is to analyze in what way the constitutional reform was intended to introduce an electoral system that would allow the elites to solve the problems of governability and representation, without significantly expanding the number of voters. The study of the elections is mainly carried as from political history, which allows for the analysis of how the constitutional reform was a strategy of the elites to reorganize the political and economic context after the thousand-day war (1898-1902), and thus avoid the development of a new conflict. Through the constitutional reform, representative democracy, centered on elections as a mechanism for legitimating power, was called for, and a new form of electoral organization was established which had its center in the capital of the country and from there links were made to the processes carried out in the departments and municipalities.
La emergencia de la oposición política en México, 1949-1952. Dos propuestas de reforma electoral
Authors: Ayala López José Fernando 
Published: February 2017

El presente artículo analiza, a partir de las herramientas metodológicas de la historia política y la historia institucional, la primera propuesta para la implementación de un sistema electoral de representación proporcional en México y sus principales repercusiones en la formulación de leyes electorales posteriores. Dicha iniciativa fue presentada por el Partido Popular ( PP ) de Vicente Lombardo Toledano, en 1951, durante la XLI Legislatura (1949-1952). Este hecho se correlaciona con la emergencia de la oposición política en la Cámara de Diputados, ya que a la par de la propuesta del PP , el Partido Acción Nacional ( PAN ), el mismo año, propuso una iniciativa de reforma electoral. Ambas propuestas propiciaron un debate legislativo que identificaba la importancia de las elecciones como instrumentos de control político por parte del Estado y proponía su reformulación. En este sentido, la principal aportación de este trabajo es hacer visibles los discursos pro reformas electorales en correlación con la emergencia de la oposición política en un período en que se suele pensar que el autoritarismo los vedaba.
Reflexiones sobre el concepto cultura política y la investigación histórica de la democracia en América Latina
Authors: Rodríguez Franco Adriana 
Published: February 2017

Este artículo tiene como objetivo reflexionar sobre cómo el concepto cultura política se ha constituido en una herramienta analítica fundamental para la historia política y, específicamente, para la historiografía que se ha dedicado en las últimas dos décadas al estudio de la instauración y desarrollo de la democracia en América Latina. Para tal fin, el texto se enfocará en el tránsito de dicha categoría desde la ciencia política hacia la historia y la forma en que esta se ha adaptado a las necesidades de interpretación histórica de las realidades políticas occidentales y latinoamericanas. Se pondrá de relieve que dicho tránsito no ha estado exento de cuestionamientos y debates, pero definitivamente ha sido un factor clave en la renovación de los estudios historiográficos sobre lo político y, particularmente, para el posicionamiento de la democracia como objeto de estudio de la historiografía latinoamericana.
Analisis Break Even Point (BEP) Usahatani Pembibitan Sapi Potong di Kabupaten Sleman
Authors: Emawati Shanti 
Published: February 2017

<p><em>The research was conducted to calculate the break even point (BEP) of cattle breeding farm. Research was done from January to May 2007, located in Sleman District. Survey methods was done to collect primary data at the farm level and secondary data from related institution. Purposive sampling was applied to sellect farmers’ respondent. The BEP with calf sales calculation of keeping Simmental, Ongole and Limousine grade cattle were 8, 9 and 7 cows per farmer respectively, which mean that farmers will annually benefited from keeping cattle when the number of cows was larger than those of BEP.</em></p><p><em> </em></p><p><em>Key words : cattle breeding farm, BEP analysis</em></p>
Integritas Advokat dan Kebebasannya Dalam Berprofesi : Ditinjau dari Penegakan Kode Etik Advokat
Authors: Nugroho Fiska Maulidian 
Published: February 2017

Profesi advokat tentu bukan semata-mata untuk mencari kekayaan secara materiil atas jasa hukumnya. Hal itu disebabkan karena setiap advokat yang menjalankan profesinya, diwajibkan untuk berpedoman kepada kode etik advokat. Perilaku seorang advokat yang menaati kode etik mencerminkan sikap patuh kepada Tuhan Yang Maha Esa, Undang-Undang Advokat, dan Kliennya. Oleh karena itu, integritas seorang advokat harus diperjuangkan, agar layak disebut sebagai officium nobile. Integritas seorang advokat dipandang harus sejajar dengan kebebasan yang didapatkan, kemandiriannya, dan rasa tanggungjawab. Tujuan penelitian ini tidak lain adalah dapat memberikan masukan terhadap integritas advokat, yang bebas seta mandiri yang tidak telepas dari tanggungjawabnya berdasarkan kode etik. Metode penelitian hukum ini menggunakan pendekatan undang-undang dan pendekatan konseptual. Selain itu kesimpulan yang didapatkan adalah, advokat patut menjaga integritasnya sebagai seorang advokat, dan berperilaku atas kode etik advokat. Namun, penegakan kode etik tersebut selama ini banyak mengalami kendala dalam penegakannya, terutama tidak adanya Wadah Tunggal Organisasi Advokat yang diatur secara tegas dan jelas. Kata Kunci : Integritas, Advokat, Kebebasan, Kode Etik
Coagulation and electrocoagulation for co-treatment of stabilized landfill leachate and municipal wastewater
Authors: Verma Mohini , Kumar R. Naresh 
Published: February 2017

Abstract
Landfill leachate and municipal wastewater at various ratios (1:20, 1:10, 1:7 and 1:5) were subjected to coagulation and electrocoagulation (EC). Alum was used in conventional coagulation at pH 6 and aluminum plate as electrode was used in EC at a current density of 386 A/m2 with 5 cm inter electrode spacing. Treatment efficiency was assessed from removal of chemical oxygen demand (COD), total suspended solids (TSS), turbidity, ammonia, nitrate and phosphate. At 1:5 ratio of landfill leachate to municipal wastewater, highest COD removal was with 3.8 g/L alum whereas highest turbidity removal was with 3.3 g/L alum during coagulation. EC exhibited almost similar removal efficiency for all the parameters at different ratios tested except for COD which was considerably higher at 1:20 ratio. Aluminum consumption from electrode was 0.7 g/L following EC as compared to 3.8 g/L alum used in coagulation. The amount of sludge produced was found to be higher with EC as compared to coagulation which could be due to the fact that the electrochemical method was performed for a longer duration than conventional coagulation. For minimal sludge generation, EC reaction time should be ∼30 min. Further studies with EC process on costing and sludge generation will help to advance the technology for wastewater treatment.