bluuebunny/crossref_metadata_2025_split huggingface dataset:
SMS education for the promotion of diabetes self-management in low & middle income countries: a pilot randomized controlled trial in Egypt
Authors: Abaza Haitham , Marschollek Michael 
Published: December 2017

Abstract
Background
Due to the ubiquity of mobile phones in low and middle income countries, we aimed to examine the feasibility of SMS education among diabetic patients in Egypt, and assess the impact of educational text messages, compared to traditional paper-based methods, on glycemic control and self-management behaviors.

Methods
We conducted a 12-week randomized controlled trial at Misr University for Science & Technology hospital in Cairo-Egypt. Known as MUST diabetes awareness program, patients were included if they had diabetes, owned a mobile phone, and could read SMS messages or lived with someone that could read for them. Intervention patients received daily messages and weekly reminders addressing various diabetes care categories. We expected greater improvement in their glycemic control compared to controls who only received paper-based educational material. The primary outcome was the change in HbA1c, measured by the difference between endpoint and baseline values and by the number of patients who experienced at least 1% reduction from baseline to endpoint. Key secondary outcomes included blood glucose levels, body weight, treatment and medication adherence, self-efficacy, and diabetes knowledge. Data were analyzed using ANCOVA, chi-square, and t-tests.

Results
Thirty four intervention and 39 control patients completed the study. Over 12 weeks, 3880 messages were sent. Each intervention patient received 84 educational and 12 reminder messages plus one welcome message. Our primary outcome did not differ significantly (Δ 0.290; 95% CI -0.402 to 0.983; p = 0.406) between groups after 3 months, demonstrating a mean drop of −0.69% and −1.05% in the control and intervention group respectively. However, 16 intervention patients achieved the targeted 1% drop versus only 6 controls, suggesting clear association between study group and 1% HbA1c reductions (chi-square = 8.655; df = 1; p = 0.003). Secondary outcomes seemed in favor of intervention patients at endpoint, with considerable improvements in treatment and medication adherence, self-efficacy, and knowledge scores. Participants also indicated full satisfaction with the program.

Conclusions
SMS education is a feasible and acceptable method for improving glycemic control and self-management behaviors among Egyptian diabetics. However, whether it is more effective than traditional paper-based methods needs further investigation.

Trial registration
ClinicalTrials.govNCT02868320. Registered 9 August 2016. Retrospectively registered.
A clinical series using intensive neurorehabilitation to promote functional motor and cognitive skills in three girls with CASK mutation
Authors: DeLuca Stephanie C. , Wallace Dory A. , Trucks Mary Rebekah , Mukherjee Konark 
Published: December 2017

Abstract
Objectives
Children with microcephaly face lifelong psychomotor, cognitive, and communications skills disabilities. Etiology of microcephaly is heterogeneous but presentation often includes seizures, hypotonia, ataxia, stereotypic movements, attention deficits, excitability, cognitive delays, and poor communication skills. Molecular diagnostics have outpaced available interventions and most children receive generic physical, speech, and occupational therapies with little attention to the efficacy of such treatments. Mutations in the X-linked intellectual disability gene (XLID) CASK is one etiology associated with microcephaly which produces mental retardation and microcephaly with pontine and cerebellar hypoplasia (MICPCH; OMIM# 300749). We pilot-tested an intensive therapy in three girls with heterozygous mutation in the gene CASK and MICPCH. Child A = 54 months; Child B = 89 months; and Child C = 24 months received a targeted treatment to improve gross/fine motor skills, visual-motor coordination, social interaction, and communication. Treatment was 4 h each weekday for 10 treatment days. Operant training promoted/refined goal-directed activities. The Peabody Developmental Motor Scales 2 was administered pre- and post-treatment.

Results
Child A gained 14 developmental months; Child B gained 20 developmental months; and Child C gained 39 developmental months. This case series suggests that children with MICPCH are responsive to intensive therapy aimed at increasing functional skills/independence.
Trial Registration ClinicalTrials.gov Registration Number: NCT03325946; Release Date: October 30, 2017
Complete genome of a novel virulent phage ST0 lysing Escherichia coli H8
Authors: Liu Honghui , Liu Xinchun , Li Jinqing 
Published: December 2017

AbstractPhage ST0 lysing Escherichia coli H8 was isolated from wastewater and sequenced using an Illumina HiSeq system. Genomic analyses revealed that it was virulent phages and contained a circular double-stranded DNA genome, consisting of 170,496 nucleotides with an average G + C content of 37.67%. This study may provide possible alternative materials for phage therapy.
Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma
Authors: Courtney Kevin D. , Infante Jeffrey R. , Lam Elaine T. , Figlin Robert A. , Rini Brian I. , Brugarolas James , Zojwalla Naseem J. , Lowe Ann M. , Wang Keshi , Wallace Eli M. , Josey John A. , Choueiri Toni K. 
Published: December 2017

Purpose The von Hippel-Lindau tumor suppressor is inactivated in the majority of clear cell renal cell carcinomas (ccRCCs), leading to inappropriate stabilization of hypoxia-inducible factor-2α (HIF-2α). PT2385 is a first-in-class HIF-2α antagonist. Objectives of this first-in-human study were to characterize the safety, pharmacokinetics, pharmacodynamics, and efficacy, and to identify the recommended phase II dose (RP2D) of PT2385. Patients and Methods Eligible patients had locally advanced or metastatic ccRCC that had progressed during one or more prior regimens that included a vascular endothelial growth factor inhibitor. PT2385 was administered orally at twice-per-day doses of 100 to 1,800 mg, according to a 3 + 3 dose-escalation design, followed by an expansion phase at the RP2D. Results The dose-escalation and expansion phases enrolled 26 and 25 patients, respectively. Patients were heavily pretreated, with a median of four (range, one to seven) prior therapies. No dose-limiting toxicity was observed at any dose. On the basis of safety, pharmacokinetic, and pharmacodynamic profiling, the RP2D was defined as 800 mg twice per day. PT2385 was well tolerated, with anemia (grade 1 to 2, 35%; grade 3, 10%), peripheral edema (grade 1 to 2, 37%; grade 3, 2%), and fatigue (grade 1 to 2, 37%; no grade 3 or 4) being the most common treatment-emergent adverse events. No patients discontinued treatment because of adverse events. Complete response, partial response, and stable disease as best response were achieved by 2%, 12%, and 52% of patients, respectively. At data cutoff, eight patients remained in the study, with 13 patients in the study for ≥ 1 year. Conclusion PT2385 has a favorable safety profile and is active in patients with heavily pretreated ccRCC, validating direct HIF-2α antagonism for the treatment of patients with ccRCC.
Reviews
Authors: Kaul Vartikka , Mukherjee Madhuja , Tanvir Kuhu 
Published: December 2017

Abstract
The Indian Graphic Novel: Nation, History and Critique, Pramod K. Nayar (2016) New York: Routledge, 212 pp., ISBN: 9781138962446, h/bk, 895 Indian Rupees
Bollywood’s India: Hindi Cinema as a Guide to Contemporary India, Rachel Dwyer (2014) London: Reaktion Books, 295 pp., ISBN: 9781780232638, p/bk, $29.00
Telemodernities: Television and Transforming Lives in Asia, Tania Lewis, Fran Martin and Wanning Sun (2016) Durham: Duke University Press, 323 pp., ISBN: 9780822362043, p/bk, $24.65; ISBN: 9780822361886, h/bk, $87.67; ISBN: 9780822373902, e-book, $23.42
La radio universitaria en su dimensión formativa: Estudio de caso de Radio Unizar
Authors: Martín-Gracia Esther , Marta-Lazo Carmen , González-Aldea Patricia 
Published: December 2017

La tipología de radios universitarias es muy heterogénea. Las creadas en las facultades de Ciencias de la Información, fundamentalmente conducidas por estudiantes de Periodismo, tienen como principal objetivo la dimensión formativa. Suponen un primer contacto profesional con el medio. El objetivo de este estudio es, a través de un análisis de caso de la dimensión formativa de Radio Unizar, hacer un diagnóstico de la situación actual y proponer posibles mejoras. La metodología se basa en dos encuestas a los alumnos participantes, así como entrevistas en profundidad a ocho personas representativas del fenómeno objeto de estudio, docentes y discentes. Los hallazgos de este estudio avalan la utilidad de las emisoras universitarias en su dimensión formativa. No obstante, frente al modelo de tutelaje entre estudiantes guiados por profesores, abogan por un modelo mixto que incluya a profesionales de la radio dedicados en exclusiva a la emisora universitaria.
Continuous Suture Technique for Aortic Valve Replacement Shortens Cross-Clamp and Bypass Times
Authors: Kitamura Tadashi , Edwards James , Miyaji Kagami 
Published: December 2017

The interrupted noneverting mattress suture technique is typically used in conventional surgical aortic valve replacement. The continuous suture technique, although faster, has been associated with a higher incidence of paravalvular leak. Using a slightly modified technique to minimize this risk, we investigated whether continuous suturing would shorten aortic cross-clamp time in aortic valve replacement in comparison with interrupted suturing.
We reviewed the cases and compared the perioperative data of 60 consecutive patients in Japan and Australia (35 men and 25 women; median age, 70 yr) who had undergone aortic valve replacement with or without septal myectomy. The continuous suture technique had been used in 41 patients (Group CS) and the standard interrupted suture technique in 19 (Group IS). The groups were similar in age, sex, pathologic valvular conditions, and operative urgency.
In Group CS, aortic cross-clamp time (47 vs 63 min; P=0.0001) and cardiopulmonary bypass time (76 vs 89 min; P=0.04) were significantly shorter. Neither group had early paravalvular leak. Using our continuous suture technique safely shortened aortic cross-clamp time during surgical aortic valve replacement.
OB Stars and Cepheids From the Gaia TGAS Catalogue: Test of their Distances and Proper Motions
Authors: Bobylev Vadim V. , Bajkova Anisa T. 
Published: December 2017

Abstract
We consider young distant stars from the Gaia TGAS catalog. These are 250 classical Cepheids and 244 OB stars located at distances up to 4 kpc from the Sun. These stars are used to determine the Galactic rotation parameters using both trigonometric parallaxes and proper motions of the TGAS stars. In this case the considered stars have relative parallax errors less than 200%. Following the well-known statistical approach, we assume that the kinematic parameters found from the line-of-sight velocities Vr are less dependent on errors of distances than the found from the velocity components Vl. From values of the first derivative of the Galactic rotation angular velocity ′0, found from the analysis of velocities Vr and Vl separately, the scale factor of distances is determined.We found that from the sample of Cepheids the scale of distances of the TGAS should be reduced by 3%, and from the sample of OB stars, on the contrary, the scale should be increased by 9%.
Worlds of Transitive Identities
Authors: Sbiri Kamal 
Published: December 2017

Abstract
In studying certain autobiographical narratives of forced migration and exile, the experience of being caught between two worlds is always emphasized. The forced migrant narrative provides different pictures of the journey from homeland to borderland, and highlights on the ruptures that identity undergoes, especially when the migrant seeks to link the pain of identity construction at a liminal phase. The experience of being lost is understood as a double movement, where in either case, identity loses its originality. Both the forced immigrant and her/his native speaker counterpart seem to exercise similar roles of translation, that is to understand and be understood. In my study of two contemporary autobiographical narratives of forced migrants, I would like to investigate how translation can help in conflating ruptures and identity construction in a transnational context. By leaning on Stephen Clingman’s theory on transnational fiction and Said’s contrapuntal analysis, I seek to emphasize the transitive elements that reside in the immigrant’s psyche. Based on this assumption, I seek to argue that both navigation within the self and recognition of displacement as an experience of mobility encourage the forced immigrant to realize her singularity as transnational.
On TSVD regularization for a Broyden-type algorithm
Authors: Smirnova Alexandra 
Published: December 2017

Abstract
An applied inverse problem in the form of a nonlinear operator equation on a pair of two Hilbert spaces is considered. In the lack of stability, a version of Broyden’s method regularized by truncated singular value decomposition (TSVD)
is proposed in order to suppress the potential noise propagation and to reduce the cost associated with storage and inversion of the Fréchet
derivative operator. An attractive feature of this study is that it does not rely on any restrictions on the nonlinearity of the operator and/or on the spectrum of the Fréchet
derivative. For the numerical analysis of the proposed algorithm, a parameter identification problem in epidemiology is investigated.
ELECTRODEPOSITION OF HYDROXYAPATITE/FUNCTIONALIZED CARBON NANOTUBES (HAp/fCNTs) COATINGS ON THE SURFACE OF 316L STAINLESS STEEL
Authors: Thom Nguyen Thi , Nam Pham Thi , Phuong Nguyen Thu , Hong Cao Thi , Trang Nguyen Van , Xuyen Nguyen Thi , Mai Thanh Dinh Thi 
Published: December 2017

The coatings of hydroxyapatite/functionalized carbon nanotubes (HAp/fCNTs) were successfully synthesized on the surface of 316L stainless steel (316L SS) by electrodeposition. To improve the dispersion of CNTs into the electrolyte, CNTs were functionalized in the mixture of 67 % HNO3 and 98 % H2SO4 before electrodeposition coatings to form fCNTs. Different amounts of fCNTs were incorporated into the apatite coatings by adding fCNTs into the electrolyte solution. In this study, Fourier Transform Infrared Spectroscopy (FT-IR), X-Ray Diffraction (XRD), Scanning Electron Microscopy (SEM), Thermal Gravimetric Analysis (TGA) and mechanical techniques were used to analyze characteristic of fCNTs and the HAp/fCNTs coatings. The FTIR spectra of CNTs before and after acid treated process show that CNTs are functionalized by chemically method with carboxylic acid groups (–COOH) on their surface. The SEM images confirm that the functionalized process by the acid mixture does not change the morphology of CNTs. The nanocomposite coatings contain single phase of HAp and CNTs with the coating thickness of 6.9 µm and the amount of fCNTs in the coatings is 7.25 %. With 0.5 g/L of fCNTs in the electrolyte solution, the solubility of the coating decreases in comparision with pure HAp coatings.
OPTIMIZATION OF THE ENZYME ASSISTED EXTRACTION OF ESSENTIAL OIL FROM THE LEAVES AND BRANCHES OF CINNAMOMUM CASSIA USING BOX-WILSON METHOD
Authors: Bich Hoang Thi , Huong Le Mai , Chien Nguyen Quyet , Thuy Dinh Thi Thu , Thanh Le Tat , Sy Do Trung , Hang Le Thi Thuy , Hai Pham Hong 
Published: December 2017

The process of enzyme assisted extraction of essential oil from the leaves and branches of the Vietnamese aromatic plant Cinnamomum cassia was studied and optimized using a Box-Wilson central composite design consisting of 05 independent variables (pH, temperature T, time τ, concentration of the enzyme Laccase, and concentration of the enzyme Cellic Htec2) and two dependent variables (reducing sugar and yield of essential oil). Second-order polynomial equations were obtained for the responses, which fitted well with the experimental data. Optimal conditions for oil yield were found at pH = 5.2; T = 440C; τ = 5h30'; Laccase = 0.42 ml/g, and Cellic Htec2 = 1.15%. The experimental value (0.982% oil yield) was close to the predicted value (0.978%). The application of enzyme assisted extraction in combination with optimization using response surface methodology substantially improved the oil yield as compared with traditional method.
(Con)Textos na linha de produção
Authors: Silva Elaine Teixeira da 
Published: December 2017

<p><strong>Resenha do livro: </strong></p><p><strong></strong>RIBEIRO, Ana Elisa. <strong>Em busca do texto perfeito:</strong> questões contemporâneas de edição, preparação e revisão textual. 1. ed. Divinópolis, MG: Artigo A, 2016.</p>
Atividades farmacológicas dos flavonoides: um estudo de revisão
Authors: Dos Santos Daniel Sousa , Farias Rodrigues Mayara Mikelle 
Published: December 2017

<p class="Body">O uso de produtos naturais como matéria-prima para a síntese de fármacos, tem sido amplamente relatado ao longo do tempo. Os flavonoides, sem dúvida, são um importante grupo dentre os produtos naturais, que vem ganhando interesse especial devido apresentarem inúmeros atividades farmacológicas. O objetivo deste estudo consistiu em abordar, por meio de pesquisa bibliográfica, algumas das principais atividades farmacológicas dos flavonoides como: atividade antiviral, antitumoral, anti-inflamatória, antioxidante, e atividade hormonal e analisar os mecanismos de ação dessas substâncias. </p>
Empirical study of effectiveness of construction waste minimization in Bauchi state
Authors: Babangida Baba , Binti Suratkon Azeanita , Bukata Yakubu Sagir Yusuf Abdullahi, 
Published: December 2017

This paper critically investigates and analysed the to determine the level of waste minimization practices in Bauchi State, Nigeria. In practice, there has been a tremendous increase in building construction which led to the generation of waste at different stages of construction. The structure of Nigerian construction industry is complex having different types of clients and contractors. This consist of public and private clients, main contractors and sub-contractors, indigenous and foreign companies, low technology firms and sophisticated specialists, builders and civil engineers and a whole range of construction professionals connected within the industry. The growing popularity of Public Private Partnership (PPPs) also means more international construction firms are likely to come into the Nigerian construction industry. The materials and methods was that questionnaire design was undertaken to determine the opinion of contractors on waste minimization practices in the study area. The sample group identified comprises project managers, project engineers, quantity surveyors, site supervisors and the method of distribution and collection of the questionnaire survey is through google by Survey Monkey. The questionnaire was constructed using Likert scale. The respondents were asked to rank on a scale of 1-5 waste minimization strategies on construction sites. The population of this research were construction firms in Bauchi participating on different types of construction projects. In this research, use of census is administered. A total number of 77 construction firms with valid registration in Nigeria. The result of the survey on the level of waste minimization practices in Bauchi construction industry. Reuse on site with the highest mean of 3.86 is in the high category and ranked first. The reuse on site is the most frequent practice on construction site. The second ranked mean is 3.57 also in the High category which represent the proportion of respondents that minimize waste at the source of origin. The finding of the research study shows that the study emphasized the Reuse is the most acceptable way of waste minimization in construction site in the study area. From the findings of this research study, its recommended that the contraction firms should have waste management plan regardless of its size as this will reduce both physical and non-physical waste and increase the profit
Effect of post-harvest application of wax-emulsion and gibberellic acid on the physical characters of kinnow mandarin fruits during storage
Authors: Rajeshree patel Anjali varshney, 
Published: December 2017

An experiment was conducted at Department of Horticulture, R.B.S.College Agra, U.P, during 1998, on effect of post-harvest application of wax-emulsion and Gibberellic acid on Kinnow mandarin during storage conducted to test the suitability of concentrations of wax and GA each at 3,6,9,12 percent and 100,200,300 ppm, respectively. The application of 9 to 12 percent wax-emulsion with 200 ppm GA could stored Kinnow mandarin fruits for a longer period at room temperature with minimum deterioration in quality was found the best treatment for the post-harvest application during storage of Kinnow mandarin under reference.
Editorial
Authors: Lombardi José Claudinei , Silva Régis Henrique dos Reis 
Published: December 2017

Na publicação do número 73 da Revista HISTEDBR Online damos sequência ao nosso compromisso de socialização do conhecimento e do pensamento crítico publicando uma variedade de temáticas da educação brasileira em uma perspectiva histórica. São publicados 14 artigos e 2 resenhas, dos quais destacamos o artigo de Marisa Bittar e Amarílio Ferreira Junior que discute o texto da última Reforma educacional realizada pela ex-União das Repúblicas Socialistas Soviéticas (ex-URSS), no ano em que lembramos dos 100 anos da Revolução Russa.
Pulsation and Collimation During Fluoroscopy to Decrease Radiation
Authors: Yamashita Kazuta , Higashino Kosaku , Hayashi Hiroaki , Hayashi Fumio , Fukui Yoshihiro , Sairyo Koichi 
Published: December 2017

Background:
Awareness of the harmful effects of long-term low-dose radiation is rising. Many studies have assessed both patient and physician exposure to radiation in association with the use of fluoroscopy in the operating room. However, to our knowledge, previous studies have not assessed, in a detailed fashion, the reduction in radiation exposure that pulsation and collimation provide.

Methods:
Seven fresh cadavers were irradiated for 5 minutes with C-arm fluoroscopy with use of standard x-ray and pulsed and collimated x-ray beams. The x-ray sources were placed under the table, over the table, and lateral to the table. Radiation exposure doses were measured at different points, such as the center of the radiation field on the cadaver as well as at the locations of the surgeon’s hand and thyroid gland. In addition, Monte Carlo simulation (a physics equation to predict exposure) was performed to estimate the dose reduction and to confirm the experimental results.

Results:
The radiation exposure doses associated with the use of pulsed fluoroscopy (8 times per second) were reduced by approximately 30% for the patient and by approximately 70% for the surgeon’s hand and thyroid gland as compared with those associated with the use of continuous fluoroscopy. The radiation exposure doses associated with the use of collimated beams were reduced to approximately 65% for the surgeon’s hand and thyroid gland as compared with those associated with the use of non-collimated fluoroscopy. These results were consistent with the simulation, and the phenomena could be appropriately explained by physics.

Conclusions:
The present study revealed the effectiveness of pulsed and collimated x-ray beams in reducing radiation exposure doses resulting from C-arm fluoroscopy. Surgeons should consider using the techniques of pulsed fluoroscopy and collimation to protect patients and themselves from radiation.

Clinical Relevance:
This study presents data regarding the reduction of radiation exposure provided by pulsed fluoroscopy and collimation.