bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Polyaromatic Molecular Clip That Enables the Binding of Planar, Tubular, and Dendritic Compounds
Authors: Jono Keisuke , Suzuki Akira , Akita Munetaka , Albrecht Ken , Yamamoto Kimihisa , Yoshizawa Michito 
Published: February 2017

AbstractBy the covalent linkage of two bent bisanthracene amphiphiles with a biphenyl spacer bearing hydrophilic pendants, we synthesized a new molecular clip with a C‐shaped conformation. The molecular clip provides an acyclic, open cavity surrounded by four anthracene panels in water. In contrast to previous clip‐ and tweezers‐like compounds as well as cage‐shaped compounds, the C‐shaped polyaromatic cavity displays unusual wide‐ranging capturing abilities toward not only planar perylene‐based pigments and cylindrical single‐walled carbon nanotubes but also highly branched macromolecules (carbazole dendrimers).
Biomimetic Total Synthesis of (±)‐Verrubenzospirolactone
Authors: Lam Hiu C. , Pepper Henry P. , Sumby Christopher J. , George Jonathan H. 
Published: February 2017

AbstractA five‐step total synthesis of (±)‐verrubenzospirolactone has been achieved using a biomimetic, intramolecular Diels–Alder reaction of a 2H‐chromene to form two rings and four stereocenters in the final step. This Diels–Alder reaction occurs spontaneously at 30 °C “on‐water”, and thus suggests that it is likely to be non‐enzymatic in nature. The structure of (±)‐verrubenzospirolactone was also used to inspire a quadruple cascade reaction to generate seven stereocenters, four rings, three C−C bonds, and two C−O bonds in one step.
Internally 2,5‐Thienylene‐Bridged [46]Decaphyrin: (Annuleno)annulene Network Consisting of Möbius Aromatic Thia[28]hexaphyrins and Strong Hückel Aromaticity of its Protonated Form
Authors: Soya Takanori , Mori Hirotaka , Hong Yongseok , Koo Yun Hee , Kim Dongho , Osuka Atsuhiro 
Published: February 2017

AbstractInternally 1,3‐phenylene‐ and 2,5‐thienylene‐bridged [46]decaphyrins 2 and 3 have been synthesized. While 2 shows modest aromatic character derived from the global 46π‐conjugated circuit, 3 displays larger aromatic character owing to the contribution of an (annuleno)annulene‐type network consisting of two twisted Möbius aromatic thia[28]hexaphyrin segments in addition to the global 46π‐network. Upon protonation, these [46]decaphyrins underwent large structural changes to acquire strong aromaticity. Protonated 3 has been revealed to take on a planar structure composed of fused two triangular thia[28]hexaphyrin segments.
Acetyl‐α‐d‐mannopyranose‐based cationic polymer via RAFT polymerization for lectin and nucleic acid bindings
Authors: Ting S. R. Simon , Min Eun Hee , Lau Benjamin K. F. , Hutvagner Gyorgy 
Published: February 2017

ABSTRACTFunctional cationic polymers carrying mannose moieties were synthesized in a facile manner by employing RAFT polymerization. Initially, a protected carbohydrate based monomer, [2‐(2,3,4,6‐tetra‐O‐acetyl‐α‐d‐mannopyranosyloxy)ethyl methacrylate (AcManEMA)], was prepared by the O‐glycosylation of 2‐hydroxyethyl methacrylate (HEMA). Subsequently, a macroRAFT agent of poly[2‐(dimethyl)amino ethyl methacrylate] (PDMAEMA) was generated, and a further chain extension polymerization with AcManEMA was carried out in dioxane to form a acetylated mannose cationic diblock copolymer, PDMAEMA‐b‐PAcManEMA. It was attained in high yields and displayed low dispersity (Ð). Acetylated mannose moieties on the polymer were deprotected with sodium methoxide and the amines from the DMAEMA block were protonated to yield a cationic diblock glycopolymer, PDMAEMA‐b‐PManEMA. The cationic property of polymers were characterized by mixing with a negatively charged siRNA duplex and a pDNA, and aggregates of 102 and 233 nm were obtained, respectively. Agarose gel shift assay revealed that the polymers were able to retain the nucleic acids as large polymer complexes. Lectin binding assay proved that the mannose residue on the polymers were only able to bind specifically with ConA. PNA lectin was employed as a control and did not show specific binding. The cationic glycopolymer could be advantageous in targeted nucleic acids delivery in specific cells. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44947.
Polyimide‐polyurethane/urea block copolymers for highly sensitive humidity sensor with low hysteresis
Authors: Bae Yu‐Mi , Lee Young‐Hee , Kim Han‐Seong , Lee Dong‐Jin , Kim Sung Yeol , Kim Han‐Do 
Published: February 2017

ABSTRACTPolyimide (PI)‐polyurethane‐urea (PU) block copolymers (PI‐PU75/25, PI‐PU50/50, and PI‐PU25/75) were prepared by reaction between anhydride‐terminated poly(amic acid) prepolymers with various number‐average degree of polymerization
= 73/49/25) and isocyanate‐terminated urethane‐urea prepolymers with various
(11/21/31) to obtain high performance capacitive humidity sensors. Pure PI and PU were also prepared to compare with PI‐PU copolymers. This study examined the effect of PU content on the water absorption %/water vapor transmission rate, thermal and mechanical properties and sensing properties of PI‐PU block copolymers. The thermal stability and mechanical properties of the copolymer decreased markedly with increasing PU content. The sensitivity of sensor increased sharply with increasing PU content from 0 to 25 wt %, and then increased a little. The hysteresis of sensor decreased sharply with increasing PU content up to 50 wt %, and then decreased a little. These results demonstrate the apparent upside of using two copolymers (PI‐PU75/25 and PI‐PU50/50) compared to using pure PI, in terms of sensor performance. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44973.
Poly(vinylidene fluoride) fibrous membranes doped with polyamide 6 for highly efficient separation of a stable oil/water emulsion
Authors: Lv Ruihua , Yin Ming , Zheng Wenzheng , Na Bing , Wang Bin , Liu Hesheng 
Published: February 2017

ABSTRACTIdeal membranes toward separation of stable oil/water emulsions should have surface hydrophilicity and submicron pores in the separating layer. However, electrospun membranes made from poly(vinylidene fluoride) (PVDF) cannot meet these requirements, failing to remove oil droplets from a stable oil/water emulsion. By doping with a certain polyamide 6 solution, surface hydrophilicity, and interconnected pores with submicron size are successfully achieved. As a result, separation of a stable emulsion with an efficiency above 99% is exhibited by the modified PVDF membranes. Moreover, underwater oleophobicity of the modified PVDF membranes imparts them with good antifouling performance. The modified PVDF membranes could have great potentials in practical stable oil/water emulsion separation. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44980.
Polyaniline‐Stabilized Intertwined Network‐like Ferrocene/Graphene Nanoarchitecture for Supercapacitor Application
Authors: Adhikari Amrita De , Oraon Ramesh , Tiwari Santosh Kumar , Jena Naresh K. , Lee Joong Hee , Kim Nam Hoon , Nayak Ganesh Chandra 
Published: February 2017

AbstractThe present work highlights the effective H–π interaction between metallocenes (ferrocene; Fc) and graphene and their stabilization in the presence of polyaniline (PANI) through π–π interactions. The PANI‐stabilized Fc@graphene nanocomposite (FcGA) resembled an intertwined network‐like morphology with high surface area and porosity, which could make it a potential candidate for energy‐storage applications. The relative interactions between the components were assessed through theoretical (DFT) calculations. The specific capacitance calculated from galvanostatic charging/discharging indicated that the PANI‐stabilized ternary nanocomposite exhibited a maximum specific capacitance of 960 F g− at an energy density of 85 Wh Kg−1 and a current density of 1 A g−. Furthermore, electrochemical impedance spectroscopy (EIS) analysis confirmed the low internal resistance of the as‐prepared nanocomposites, which showed improved charge‐transfer properties of graphene after incorporation of Fc and stabilization with PANI. Additionally, all electrodes were found to be stable up to 5000 cycles with a specific capacitance retention of 86 %, thus demonstrating the good reversibility and durability of the electrode material.
Synthesis of N,N‐Dialkylamino‐nor‐Dihydroxanthene‐Hemicyanine Fused Near‐Infrared Fluorophores and Their First Water‐Soluble and/or Bioconjugatable Analogues
Authors: Ong Michelle Jui Hsien , Debieu Sylvain , Moreau Mathieu , Romieu Anthony , Richard Jean‐Alexandre 
Published: February 2017

AbstractThe effective synthesis of extended conjugated N,N‐dialkylamino‐nor‐dihydroxanthene‐based fluorophores is described from diversely functionalized salicylic aldehydes. The access to these original fluorescent derivatives proceeded in two steps through a one‐pot construction of the unusual nor‐dihydroxanthene (nor‐DHX) scaffold followed by a diversification step providing a wide variety of nor‐DHX‐hemicyanine fused dyes emitting in the range of 730–790 nm. The versatility of our approach has enabled a further extension to the late‐stage introduction of negatively/positively charged polar groups onto their terminal nitrogen heterocyclic subunit, thereby giving access to the first water‐soluble and/or bioconjugatable members of this emerging class of NIR fluorophores. Our water‐solubilizing method is easily implementable, and the nor‐DHX‐hemicyanine skeleton maintains satisfying fluorescence quantum yields (5–20 %) under physiological conditions. Finally, the bioconjugation ability of fluorescent derivatives bearing a free carboxylic acid was demonstrated through the covalent labeling of a model protein, namely, bovine serum albumin.
Sustainability in The Banking Industry: A Strategic Multi‐Criterion Analysis
Authors: Raut Rakesh , Cheikhrouhou Naoufel , Kharat Manoj 
Published: February 2017

AbstractThe current paper aims to develop an effective and integrated MCDM model for the evaluation of the sustainability practices in the banking services, employing a multi‐stage, fuzzy MCDM model that integrates the Balanced Scorecard, fuzzy AHP and fuzzy TOPSIS. The approach aims to evaluate sustainability from the following four perspectives: financial stability, customer relationship management, internal business process and environment‐friendly management system. A real implementation dealing with the six largest commercial banks in India is discussed. The results highlights the critical aspects of the evaluation criteria and the issues in improving sustainable banking performances. Regarding the sustainability issues, it is shown that the environment‐friendly management system takes a back seat compared with the other criteria. Furthermore, the results show that there is a misunderstanding of the role that corporate social responsibility plays with respect to environmental issues. The developed evaluation model offers a valuable management tool for banks' administrators by assisting them in strategic choices in order to achieve their objective of sustainability and sustainable banking. Moreover, it offers a measuring tool with unique features that complements the emerging trend of integrated reporting considering uncertainty. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
MiR‐144 affects fatty acid composition by regulating ELOVL6 expression in duck hepatocytes
Authors: He Jun , Tian Yong , Zhao Yan , Liu Yali , Tao Zhengrong , Li Guoqin , Niu Dong , Lu Lizhi , Lu Yingru 
Published: February 2017

AbstractLipid metabolism in duck is very important for both raisers and people's health. In our previous studies, we have detected that miR‐144 is related to duck lipid metabolism and validated one of its target genes, elongation of very long chain fatty acids protein 6 (ELOVL6). In the present study, we isolated, cultured, and identified duck hepatocytes, and transfected with miR‐144 mimics/inhibitor to mediate the miR‐144 level. The qRT‐PCR results showed that the ELOVL6 expression in duck hepatocytes was down/upregulated, respectively. The fat contents and each fatty‐acid percent content of the hepatocytes and medium were also determined. When ELOVL6 expression suppressed (miR‐144 mimics transfected), the palmitic acid (C16:0) content was significantly increased (P < 0.05); the oleic acid (C18:1, n‐9), eicosenoic acid (C20:1, n‐9), and eicosatrienoic acid (C20:3) contents were significantly reduced (P < 0.05). The myristic acid (C14:0) and palmitic acid (C16:0) contents were significantly reduced (P < 0.05), and the oleic acid (C18:1, n‐9) content was significantly increased (P < 0.05) when ELOVL6 expression upregulated (miR‐144 inhibitor transfected). It indicated that miR‐144 could regulate some saturated fatty acids elongated to longer unsaturated fatty acids through controlling ELOVL6 expression. Whereas, miR‐144/ELOVL6 appeared not associated with fat deposition in duck hepatocytes (P > 0.05). Our findings suggest that miR‐144 might regulate the percentages of fatty acids in duck hepatocytes through affecting ELOVL6 expression.
Self‐assembly‐ and Preshaping‐assisted Synthesis of Molybdenum Carbide Supported on Ultrathin Nitrogen‐doped Graphitic Carbon Lamellas for the Hydrogen Evolution Reaction
Authors: Peng Lishan , Nie Yao , Zhang Ling , Xiang Rui , Wang Jun , Chen Hongmei , Chen Ke , Wei Zidong 
Published: February 2017

AbstractHerein, we report a self‐assembly and preshaping strategy for the controllable synthesis of highly dispersed Mo2C nanoparticles supported on porous graphitic carbon lamellas. This simple but effective method prevents the serious overlapping of carbon and excessive growth of Mo2C and endows Mo2C/C with a 2 D lamellar structure even after high‐temperature carburization. The constructed Mo2C/C‐lamellas exhibits higher activity in the hydrogen evolution reaction than traditional bulk Mo2C/C and shows long‐term stability. This self‐assembly and preshaping assisted carburization method represents a rational strategy for the preparation of robust carbon composite materials with hierarchically ordered structures, especially high melting points, and a high tendency to undergo aggregation.
Bis‐picolinamide Ruthenium(III) Dihalide Complexes: Dichloride‐to‐Diiodide Exchange Generates Single trans Isomers with High Potency and Cancer Cell Selectivity
Authors: Basri Aida M. , Lord Rianne M. , Allison Simon J. , Rodríguez‐Bárzano Andrea , Lucas Stephanie J. , Janeway Felix D. , Shepherd Helena J. , Pask Christopher M. , Phillips Roger M. , McGowan Patrick C. 
Published: February 2017

AbstractA library of new bis‐picolinamide ruthenium(III) dihalide complexes of the type [RuX2L2] (X=Cl or I, L=picolinamide) have been synthesised and characterised. The complexes exhibit different picolinamide ligand binding modes, whereby one ligand is bound (N,N) and the other bound (N,O). Structural studies revealed a mixture of cis and trans isomers for the [RuCl2L2] complexes but upon a halide exchange reaction to yield [RuI2L2], only single trans isomers were detected. High cytotoxic activity against human cancer cell lines was observed, with the potencies of some complexes similar to or better than cisplatin. The conversion to [RuI2L2] substantially increased the activity towards cancer cell lines by more than twelvefold. The [RuI2L2] complexes displayed potent activity against the A2780cis (cisplatin‐resistant human ovarian cancer) cell line, with a more than fourfold higher potency than cisplatin. Equitoxic activity was observed against normoxic and hypoxic cancer cells, which indicates the potential to eradicate both the hypoxic and aerobic fractions of solid tumours with similar efficiency. The activity of selected complexes against non‐cancer ARPE‐19 cells was also tested. The [RuI2L2] complexes were found to be more potent than the [RuCl2L2] analogues and also more selective towards cancer cells with a selectivity factor in excess of sevenfold.
Frozen Chirality of Tertiary Aromatic Amides: Access to Enantioenriched Tertiary α‐Amino Acid or Amino Alcohol without Chiral Reagent
Authors: Mai Thi Thoa , Viswambharan Baby , Gori Didier , Guillot Régis , Naubron Jean‐Valère , Kouklovsky Cyrille , Alezra Valérie 
Published: February 2017

AbstractOne of the fundamental and intriguing aspects of life is the homochirality of the essential molecules. In this field, the absolute asymmetric synthesis of α‐amino acids is a major challenge. Herein, we report access, by chemical means, to tertiary α‐amino acid derivatives in up to 96 % ee without using any chiral reagent. In our strategy, the dynamic axial chirality of tertiary aromatic amides is frozen in a crystal and is responsible for the stereoselectivity of the subsequent steps. Furthermore, we could control the configuration of the final product by manually sorting and selecting the initial crystals. Based on vibrational circular dichroism studies, we could rationalize the observed stereoselectivity.
Simulation of bubbling fluidized beds with cohesive particles by incorporating a novel structure‐Based drag model into the two‐fluid model
Authors: Luo Chuanbao , Zheng Wei , Xu Liping , Pan Mingxi , Zhou Tao 
Published: February 2017

AbstractA novel structure‐based drag model was proposed to study the hydrodynamics of bubbling fluidized beds (BFBs) operated with ultrafine cohesive particles by considering local heterogeneous flow structures. Firstly, a local structure parameters model capturing the internal flow structures of the studied system was built by balance equations and empirical formulas and the solutions (i.e. local structure parameters) of this model solved by global search algorithm were evaluated in terms of hydrodynamics, energy consumption, and voidage. Then the local structure parameters were employed to derive the structure‐based drag model. Lastly, three drag models (i.e. the structure‐based drag model, Gidaspow model, and Syamlal‐O'Brien model) were investigated and incorporated separately into the two‐fluid model, where the simulation results were also separately compared with available experimental data. The comparison shows that Gidaspow and Syamlal‐O'Brien drag models failed to predict the solid volume fraction profiles. However, the error analysis results of the structure‐based drag model indicate the average absolute relative error of solid volume fraction in the radial direction is 7.04 % and 5.64 % at the height of 0.1 m and 0.2 m respectively, which exhibits promising predictions. Thus, it is feasible to simulate the BFBs with cohesive particles through the combination of the structure‐based drag model with the two‐fluid model.
Prediction of spout diameter in gas‐solid spouted beds using factorial design of experiments approach with the aid of advanced optical fibre probe
Authors: Al‐Dahhan Muthanna , Aradhya Shreekanta , Taofeeq Haidar 
Published: February 2017

ABSTRACTIn this study, the effects of five operating and design variables (solid density, static bed height, particle diameter, superficial gas velocity, and inlet diameter) on the average spout diameter of a 0.152 m inside diameter gas‐solid spouted bed have been assessed experimentally using advanced gas‐solid optical fibre probe technique. Statistical analysis of the experimental data including the factorial design of the experiments using MINITAB17 statistical software has been performed to determine the extent of the effects of these variables on the spout diameter as a case study. It was found that all five operating and design variables, except the solid density together with the 2‐ways interactions between particles size and inlet diameter, in addition to gas velocity and inlet diameter, have a significant effect on the average spout diameter. Regression analysis was performed to correlate these variables with the average spout diameter for the gas‐solid spouted beds. The obtained preliminary regression correlation was able to closely predict the average spout diameter of this work with the mean relative deviation value of 0.7 %.
One‐Pot Synthesis of Chloromethylated Mesoporous Silica Nanoparticles as Multifunctional Fillers in Hybrid Anion Exchange Membranes
Authors: He Xueyi , Gang Mingyue , He Guangwei , Yin Yongheng , Cao Li , Wu Hong , Jiang Zhongyi 
Published: February 2017

AbstractChloromethylated mesoporous silica nanoparticles (CM MSN) were synthesized through co‐condensation of tetraethoxysilane and (chloro) phenyltrimethoxysilane precursors using hexadecyl trimethyl ammonium bromide as template. With the addition of the particles into chloromethylated poly (ether ether ketone) (PEEK), the hybrid membranes were prepared by a solution‐casting method after complete quaternization of the casting solution. The successful synthesis of the particles was verified by transmission electron microscopy, X‐ray diffraction and Fourier transform infrared spectroscopy while the effect of CM MSN incorporation on membrane performance including thermal stability, mechanical strength and hydroxide conductivity was investigated by thermal gravimetric analysis, electronic stretching machine, alternating‐current impedance and so on. Owing to the large pore volume and high surface area of the particles, the hybrid membranes exhibited enhanced hydroxide conductivity (88.7% increase at 60 °C, 100% RH with 5.0 wt% filling content) due to an increase in ion concentration and optimization of the channel morphology. Besides, higher mechanical strength, thermal and dimensional stability of hybrid membranes were obtained compared with those of the imidazolium PEEK membrane.
Iron‐Catalyzed Oxidative Cyclization of 1,6‐Enones with Aldehydes: Synthesis of Functionalized 3,4‐Dihydro‐2H‐pyrans
Authors: Lv Leiyang , Li Zhiping 
Published: February 2017

AbstractAn iron‐catalyzed cyclization of 1,6‐enones with aldehydes was developed. With this method, a variety of poly‐functionalized 3,4‐dihydro‐2H‐pyrans were prepared efficiently and selectively. The 6‐endo‐trig radical cyclization onto the keto oxygen is the key step of this transformation.
Patient‐specific computational modeling of cortical spreading depression via diffusion tensor imaging
Authors: Kroos Julia M. , Marinelli Isabella , Diez Ibai , Cortes Jesus M. , Stramaglia Sebastiano , Gerardo‐Giorda Luca 
Published: February 2017

AbstractCortical spreading depression, a depolarization wave originating in the visual cortex and traveling towards the frontal lobe, is commonly accepted as a correlate of migraine visual aura. As of today, little is known about the mechanisms that can trigger or stop such phenomenon. However, the complex and highly individual characteristics of the brain cortex suggest that the geometry might have a significant impact in supporting or contrasting the propagation of cortical spreading depression. Accurate patient‐specific computational models are fundamental to cope with the high variability in cortical geometries among individuals, but also with the conduction anisotropy induced in a given cortex by the complex neuronal organisation in the grey matter. In this paper, we integrate a distributed model for extracellular potassium concentration with patient‐specific diffusivity tensors derived locally from diffusion tensor imaging data.