bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exenatide improves β-cell function up to 3 years of treatment in patients with type 2 diabetes: a randomised controlled trial
Authors: van Raalte Daniël H , Bunck Mathijs C , Smits Mark M , Hoekstra T , Cornér Anja , Diamant Michaela , Eliasson Bjorn ,   Marja-RiittaTaskinen, Heine Robert J , Smith Ulf ,   HanneleYki-Järvinen, Mari Andrea 
Published: July 2016

Objective
Glucagon-like peptide (GLP)-1 receptor agonist treatment improves β-cell function. In this study, we investigated whether the improvements are sustained during a 3-year treatment period.

Research design and methods
Sixty-nine metformin-treated type 2 diabetes patients were randomised to the GLP1 receptor agonist, exenatide (EXE) twice daily (BID) or to insulin glargine (GLAR). β-cell function parameters were derived using the Mari model from standardised breakfast and lunch meals that were administered before treatment, and after 1 and 3 years of treatment. EXE was administered before breakfast.

Results
Fifty-nine (EXE: n = 30; GLAR: n = 29) and thirty-six (EXE: n = 16; GLAR: n = 20) patients completed the meal at 1- and 3-year treatment respectively. After 3 years, groups had comparable glycaemic control (HbA1c: EXE 6.6 ± 0.2% and GLAR 6.9 ± 0.2%; P = 0.216). Compared with GLAR, at 1 and 3 years, EXE induced a stronger reduction in post-breakfast glucose concentrations (P < 0.001), with lower C-peptide levels (P < 0.001). Compared with GLAR, EXE increased insulin secretion at 8 mmol/L glucose throughout the study period (P < 0.01). Both treatments improved β-cell glucose sensitivity after 1-year treatment. However, only EXE treatment sustained this improvement for 3 years. No consistent changes in other β-cell parameters including rate sensitivity and potentiation were observed.

Conclusions
Compared with GLAR, EXE improved the parameters of β-cell function, especially insulin secretion at 8 mmol/L glucose and β-cell glucose sensitivity, which was sustained during the 3-year treatment period.
Kloning Manusia Perspektif Hukum Islam Di Indonesia
Authors: Jamaa La 
Published: July 2016

Abstract:Reproductive cloning technology is able to facilitate artificial fertilization by using the husband's body and wife's ovum, as well the embryo transferred to the womb of the wife. So that, human cloning can give benefit to husband and wife to get child. However, human cloning technology has negative implications in case of marriage, jurisprudence, guardianship, inheritance, and investigation of criminal offense, because a person may have children cloned without marital status that can underestimate the institution of marriage. The “Nasab” of cloned child is also unclear, so it affects the guardianship, inheritance, father's responsibility to the child. Therefore, Islamic law in Indonesia prohibits human cloning.Keywords: Human Cloning, Islamic Law, Marriage. Abstrak.Teknologi kloning reproduksi mampu memfasilitasi pembuahan buatan dengan menggunakan sel tubuh suami dan ovum istri, serta embrionya ditransfer ke rahim istri. Sehingga kloning manusia dapat memberikan kemaslahatan terhadap pasangan suami istri yang tidak subur untuk memperoleh keturunan. Namun demikian, teknologi kloning manusia berimplikasi negatif, baik terhadap institusi perkawinan, nasab, perwalian, kewarisan, serta penyelidikan dan penyidikan pelaku tindak pidana. Sebab seseorang bisa punya anak secara kloning tanpa ikatan perkawinan sehingga bisa menyepelekan institusi perkawinan. Nasab anak hasil kloning juga tidak jelas sehingga berpengaruh pada perwalian, kewarisan, tanggungjawab ayah kepada anak dan sebaliknya. Karena itu hukum Islam di Indonesia melarang kloning manusia.Kata Kunci: Kloning Manusia, Hukum Islam, Perkawinan.
Automatisierte Fruchtbarkeits- und Gesundheits - überwachung bei der Milchkuh
Authors: Martin Rainer , Zerbe Holm , Zimmermann Lisa 
Published: July 2016

ZusammenfassungDurch Zunahme der Betriebsgrößen bei gleichbleibender Arbeitskraft, leistungsbedingte Krankheitsanfälligkeit der Tiere und Zwang zur Wirtschaftlichkeit der Betriebe kommt automatisierten Überwachungssystemen im Milchviehbereich immer größere Bedeutung zu. Der Markt bietet bereits eine Reihe von Systemen zur Überwachung der Milchkuh für verschiedene Managementbereiche. Nicht immer liegt eine wissenschaftliche Validierung ihrer Eignung vor, die aufgrund der nicht unerheblichen Investitionskosten sowie zur Beurteilung der Praktikabilität eines Systems jedoch wünschenswert wäre. In Anbetracht der Entwicklung der letzten Jahre ist auch in den kommenden Jahren mit einem großen Fortschritt auf dem Gebiet der automatisierten Tierüberwachung zu rechnen. Für Tierärzte ergibt sich daher die Notwendigkeit, künftig Prinzipien entsprechender Systeme zu kennen, deren Nützlichkeit einschätzen und mit resultierenden Daten arbeiten zu können, um eine adäquate Beratung der betreuten Betriebe zu gewährleisten. Ziel dieses Übersichtsartikels ist, Möglichkeiten und Grenzen derzeit verfügbarer Überwachungsinstrumente der Brunst, der Geburt und des Gesundheitsstatus (insbesondere der Stoffwechsellage) bei der Milchkuh, aber auch einzelner speziell ausgewählter Überwachungsbereiche darzustellen.
ESCRITURA, VERDADE, VIRTUDE
Authors: Pissarra Maria Constança Peres 
Published: July 2016

O texto, “Os devaneios de um caminhante solitário” é uma obra póstuma e inacabada, cujo inicio ocorreu em 1776 e a redação continuou até 1778 quando foi interrompida pela morte de seu autor, Jean-Jacques Rousseau. Nos parágrafos iniciais, ele a define como a obra de um homem que não esperava mais nada do mundo, que vivia apenas de suas lembranças e que escrevia tão somente para si mesmo: “Eis-me, portanto, sozinho na terra, tendo apenas a mim mesmo como irmão, próximo, amigo, companhia”. […] Tudo está acabado para mim sobre a terra. […] Sózinho pelo resto de minha vida, visto que somente em mim encontro a consolaçao, a esperança e a paz, não devo nem quero mais ocupar-me senão comigo mesmo é nesse estado que retomo a continuação do exame severo e sincero que outrora chamei minhas Confissões” (ROUSSEAU, 1995, p. 23 e 26).Palavras-chave: Devaneios de um caminhante solitário. Confissões. Lembranças. Devaneios. SCRIPTURE, TRUTH, VIRTUE Abstract: The text, Reveries of a Solitary Walker, is a posthumous and unfinished work, which began in 1776and the writing continued until 1778 when it was interrupted by the death of its author, Jean-Jacques Rousseau. Inthe opening paragraphs, he defines this work like a man who did not expect anything else in the world, who livedonly by his remembrance and who wrote only for himself, “Here I am, therefore, alone on earth, having just myselfas a brother, as neighbor, as friend, as companion “. [...] It’s all over for me on earth. [...] Alone for the rest of my life,since is only in myself that I find solace, hope and peace, It’s my duty and my wish to be concerned entirely with myself,in that state that I return and continued the severe and sincere examination that once I called my Confessions”(ROUSSEAU, 1995, p. 23 e 26).Keywords: Reveries of a Solitary Walker. Confessions. Remembrance. Reveries. ESCRITURA, VERDAD, VIRTUDResumen: El texto "Los devaneos de un caminante solitario" es una obra póstuma e inacabada que se inició en 1776 y cuya redacción continuó hasta 1778 cuando fue interrumpida por la muerte de su autor, Jean-Jacques Rousseau. En los parágrafos iniciales, él a define como la obra de un hombre que no esperaba más nada del mundo, que vivía apenas de sus recuerdos y que escribía unicamente para sí mismo. “Estoy, por lo tanto, solo en la tierra, tengo solamente a mí mismo como hermano, vecino, amigo, compañía" [...] Todo está acabado para mí sobre la tierra […] Solo por el resto de mi vida, visto que solamente en mí encuentro consuelo, esperanza y paz, no debo ni quiero más ocuparme a no ser conmigo mismo y es en este estado que retomo a continuación del examen severo y sincero que antes llamé mis Confesiones" (ROUSSEAU, 1995, p. 23 e 26).Palabras clave: Devaneos de un caminante solitário. Confesiones. Recuerdos. Rousseau.
A CORPOREIDADE NO ENSINO DE TEATRO: para onde apontam os PPCs das licenciaturas em teatro das universidades federais brasileiras?
Authors: Gonçalves Amanda Diniz , Sampaio Juliano Casimiro De Camargo 
Published: July 2016

Nesta pesquisa analisamos a natureza das referências bibliográficas básicas e complementares das licenciaturas em teatro das universidades federais brasileiras, bem como a presença de indicações sobre o trabalho do ator e sobre o ensino de teatro nos ementários das disciplinas que tomam o corpo como foco. Realizamos análise quantitativa e qualitativa de documentos (Projetos Pedagógicos de Curso). Resultou que tanto as bibliografias quanto as ementas das disciplinas analisadas estão consideravelmente mais voltadas para as práticas do ator do que para o ensino de teatro, bem como evidenciamos a ausência textual das palavras experiência, metodologia e didática no todo das ementas analisadas.Palavras-chave: Licenciatura. Teatro. Ensino. Ementário. CORPORALITY IN THE DRAMA TEACHING: the Educational Program of Course of the drama degree of the brazilian federal universities point to where?Abstract: In this paper we analyze the nature of the references of the degree in drama of the brazilian federal universities. We analyze too the presence of the indications about both the actor’s work and the teaching of drama in the programs of the courses that take the body as focus. The methodology used was documental research with both quantitative and qualitative analyzes of the Educational Program of Course (EPC). Resulted that the references and the programs of studies of the analyzed courses are considerable more focused in the actor’s work than in teaching drama. We noted too the absence of the following words: experience, methodology and didactic, in the analyzed programs of studies.Keywords: Degree. Drama. Teaching. Program of course. LA CORPOREIDAD EN LA ENSEÑANZA DE TEATRO: Para dónde apuntan los Proyectos Pedagógicos de las Licenciaturas en Teatro de las Universidades FederalesResumen: En esta investigación analizamos la naturaleza de las referencias bibliográficas básicas y complementarias de las licenciaturas en teatro de las universidades federales brasileñas, así como, la presencia de indicaciones sobre el trabajo del actor y sobre la enseñanza de teatro en los programas educacionales de las asignaturas que toman el cuerpo como foco. Realizamos análisis cuantitativo y cualitativo de los documentos (Proyectos Pedagógicos de Curso). Resultó que tanto las bibliografías cuanto los programas educacionales de las disciplinas analizadas están considerablemente más direccionados para las prácticas del actor que para la enseñanza de teatro, así como, evidenciamos la ausencia textual de las palabras experiencia, metodología y didáctica en el total de los programas de los cursos analizados. Palabras Clave: Licenciatura. Teatro. Enseñanza. Programa de Curso.
Transcondylar Fracture-Dislocation of the Elbow
Authors: Sameer M. Mohamed , Bassetty Keerthy Chandra , Singaravadivelu Vaidyanathan 
Published: July 2016

Case:
Transcondylar fracture of the distal part of the humerus with associated dislocation (Posadas fracture) is rare. Stabilization of this fracture is often difficult because the distal fragments are small and are predominantly composed of impacted articular cartilage.

Conclusion:
We report the case of a patient in whom this rare fracture, which was associated with a brachial artery injury, was successfully treated with internal fixation.
More Exact Measures Raise Tough Questions: Regulators and Drillers Adjust to Precise Fluid Flow Measures
Authors: Rassenfoss Stephen 
Published: July 2016

Riser Gas
More precise measurement can create a dilemma.
One example is the precise fluid flow measurements used to control managed pressure drilling (MPD) systems.
By measuring differences as small as 1 bbl in the drilling fluid flowing out of a well compared to what flowed in, these closed well designs are able to quickly adjust the downhole pressure to manage an influx, or drilling fluid loss.
MPD has allowed development of difficult formations, particularly in Southeast Asia, where conventional drilling methods would have taken far longer for many wells, if they could have been drilled at all, in unpredictable carbonate formations prone to massive fluid losses. One MPD advocate, Peter Aird, a drilling consultant who is founder of Kingdom Drilling Services, said MPD should stand for “makes problems disappear.”
The dilemma is a result of regulations prohibiting offshore drillers in the US from “knowingly” taking a kick. The rule was written back when the smallest kick that a driller could knowingly have taken was roughly 10 times larger than what an MPD system can accurately measure.
Drillers have been trained to react to kicks, which can be a warning sign of a potentially bigger surge of oil or natural gas to come, by resorting to traditional well control methods, beginning with using the blowout preventer (BOP) to shut in the well below the riser. That approach is costly, time consuming, and can damage the well, forcing the operator to abandon a section of the hole.
The dilemma is not just a product of regulation. For managed pressure systems to work efficiently, thorough training is required so drillers understand a method that requires them to think differently. Often MPD systems are brought in relatively late in project planning, leaving little time to get workers comfortable with the process, said Robert Ziegler, president of RZI Deepwater, a drilling consulting firm.
Resolving Mixed-Salinity Challenges With a Pulsed-Neutron Methodology
Authors: Carpenter Chris 
Published: July 2016

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 170608, “Resolving Mixed-Salinity Challenges With a Methodology Developed From Pulsed-Neutron-Capture Gamma Ray Spectral Measurements,” by S. Mark Ma, SPE, Saudi Aramco; Harold Pfutzner, SPE, Schlumberger; A.A. Al-Hajari, SPE, and Nedhal M. Musharfi, SPE, Saudi Aramco; and Pablo Saldungaray, SPE, and Hisham Azam, SPE, Schlumberger, prepared for the 2014 SPE Annual Technical Conference and Exhibition, Amsterdam, 27–29 October. The paper has not been peer reviewed.
The mixed-salinity environment poses a significant challenge in petrophysics. The industry still lacks a workable solution for accurate formation measurements in the presence of variable or unknown water salinity, especially in reservoir surveillance. A pulsed-neutron (PN) spectroscopy tool was characterized by use of laboratory limestone formations and with data generated through Monte Carlo simulation. Results from a number of measurements obtained were compared with values determined from formation-tester samples, demonstrating that a solution for accurate formation-water-salinity (FSAL) determination has been established.
A Domain Splitting-Based Analytical Approach for Assessing Hydro-Thermo-Geomechanical Responses of Heavy-Oil Reservoirs
Authors: Hosseini Behrooz Koohmareh , Chalaturnyk Rick 
Published: July 2016

SummaryFor stress-sensitive heavy-oil reservoirs, geomechanical responses of the reservoir are taken into account because they play an important role in the accurate simulation of all thermal recovery techniques, such as steam-assisted gravity drainage (SAGD) or steamflood. However, full-field numerical simulations of multiphysics processes by any coupling strategies are technically impossible with current computer central processing units (CPUs). Under these conditions, analytical methods can be used as approximate techniques instead of numerical simulators because they are much faster and yet are useful tools for preliminary forecasting and sensitivity studies. In analytical models, inclusion of all flow-variable impacts into geomechanics frameworks make the equations complex and almost impossible to solve. This paper provides a flow-based domain decomposition work flow for performing different analytical coupling schemes in different reservoir compartments.Because the intensity and complexity of reservoir geomechanics vary over reservoir domain, one can divide the reservoir to some subdomains and assess different geomechanical responses separately in each subdomain. The presented analytical proxy suggests decomposition of the entire domain into two parts of “heated zone” and “wetted zone,” for rapid assessment of geomechanics. The heat-flow equation was combined with mass and momentum convective-transport equations to obtain an exact approach that correlates the saturation front of injected hot water to temperature front. The frontal velocities are dynamic interfaces for compartmentalization of the domain. In the heated zone, the total induced stresses were considered because both temperature and pressure increase, and in the wetted (saturated) zone beyond the temperature front, at each instance, the total stress induced is only a function of pressure increase, and, accordingly, stress and strain induced are caused by isotropic unloading. This technique provides a rapid estimate of geomechanical responses (stress and strain profile) in each part of the reservoir (near field and far field).A numerical model was built and implemented in CMG-STARS for a steamflood case to show the robustness and applicability range of the model. The results were analyzed for a synthetic-case single-domain model, and the model sensitivity on some reservoir parameters was checked, while geomechanical responses were not neglected anywhere (near field and far field) in the reservoir. The results of the numerical model were in close agreement with the result of the proposed analytical proxy.
Response of Land Configuration and Mulches on Maize–Frenchbean–Toria Cropping System
Authors: Choudhary V. K. 
Published: July 2016

Alteration in soil‐topography and placement of mulches could play an important role in in situ conservation of resources. The objective of this study was to assess the productivity, water use, and weed smothering in the rainfed maize (Zea mays L.)–frenchbean (Phaseolus vulgaris L.)–toria (Brassica campestris L.) cropping system. Results revealed that the yield improvement under broad bed and furrow (BBF) was noticed up to 33.7% in maize grain, 35.3% in frenchbean green pod, and 28.2% in toria seeds followed by ridges and furrow (R&F) over flat bed (FB). Placement of mulch improved the crop yield by 14.2, 14.4 and 12.4%, respectively than without mulch plots. The FB plots recorded with profuse growth of weeds and obtained highest weed dry biomass. Weed smothering efficiency (WSE) improved by 43.6 to 65.1% in BBF and 54.4 to 72.8% with mulch over FB and without mulch, respectively. Maize and frenchbean under FB plots utilized 43.1 and 14.2% more rain water than the R&F, whereas, R&F plots in toria utilized 12% more than FB plots. The BBF improved the water‐use efficiency (WUE) by 77.9, 40.6, and 37.2% respectively in maize, frenchbean, and toria over FB plots. Placement of mulch utilized the rain water to the tune of 10.4 to 36.1% higher, but WUE was considerably improved by 7.8 and 21.2%, respectively with frenchbean and toria under without mulch plots. Permanent beds along with crop residues as mulch can be utilized as promising resource conserving sustainable production technology in Southeast Asia.Core Ideas

Land configuration and mulches improved the crop productivity.
Highest weed smothering obtained under broad bed and furrow with mulch.
Water‐use efficiency improved under broad bed and furrow along with mulch.
TWO-DIMENSIONAL FLAME INSTABILITY AND CONTROL OF BURNING IN THE HAlF-OPEN FIRECHAMBER
Authors: Volkov V. E. 
Published: July 2016

The flame stability with regard to two-dimensional exponential perturbations both for the combustion in the half-open fire-chamber and the flame propagating in half-open channels is investigated. It is proved that only instability ispossible for the combustion process. At the same time the one-dimensional flame instability is guaranteed near the front wall of the fire-chamber where the fuel supply is realized. Possibilities for the control of combustion in the halfopenfire-chamber and diminishing of intensity of pulsations are discussed.
АВТОМАТИЗАЦІЯ АНАЛІЗУ КАР’ЄРНОГО РОЗВИТКУ ТА ПІДТРИМКА ПРИЙНЯТТЯ РІШЕНЬ ЩОДО АТЕСТАЦІЇ РОЗРОБНИКІВ ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ
Authors: Водолазкіна К. О. 
Published: July 2016

Розглянуто проблему збору та аналізу даних для HR менеджерів в ІТ-компанії. Запропоновано розробити автоматизовану система аналізу даних персоналу і відстеження професійної майстерності співробітниківкомпанії. Система виконує збереження та аналіз особистих даних, підтримку прийняття рішень в управлінні персоналом. Для вирішення проблеми запропоновано використовувати метод домінування за Парето.Розроблений підхід дозволяє HR-менеджерам аналізувати професійні зростання всіх співробітників та прийняти краще управлінське рішення.
КОМПЬЮТЕРНО-ИНТЕГРИРОВАННАЯ СИСТЕМА УПРАВЛЕНИЯ ПЕРЕСТАНОВКАМИ ТВС В АКЗ ВВЭР-1000 С УЧЕТОМ ПОВРЕЖДЕННОСТИ ОБОЛОЧЕК ТВЭЛОВ
Authors: Стефаник В. М. 
Published: July 2016

Методика расчета повреждения оболочек твэлов ВВЕР- 1000 основана на энергетическом варианте теории ползучести, который является экспериментально подтвержденным. Результаты расчета, которые позволяютнаходить алгоритмы перестановок ТВЗ с минимизацией вероятности разгерметизации оболочек, могут быть использованы при проектировании компьютерно-интегрированной системы управления (КИСУ) реакторомВВЕР- 1000. Предложенная структура КИСУ, которая может быть использована при разрабатывании инновационной технологии повышения безопасности и надежности эксплуатации ядерного топлива ВВЕР-1000 за счет уменьшения вероятности разгерметизации оболочек твэлов за механизмом деформационногоповреждения.
Ter equilíbrio, para dar equilíbrio
Authors: Niemeyer da Rocha Fátima 
Published: July 2016

Trata-se da resenha do livro "Ter equilíbrio, para dar equilíbrio. Profissão psicólogo? Um estudo sobre as representações sociais dos alunos de um curso de psicologia" de Ively Guimarães Abdalla. O texto resenhado relata os resultados de uma pesquisa sobre como o aluno do curso de psicologia constrói, no cotidiano de sua atividade discente, a sua identidade como profissional. Trata-se de uma investigação a respeito das representações sociais que os alunos de psicologia elaboram sobre a carreira/profissão e o ser psicólogo, com o objetivo de acompanhar e entender o processo de construção da sua identidade profissional, no decorrer de sua formação, e como a representação social se integra na sua prática.
Regeneration of coppice
Authors: Lust N. , Mohammady M. 
Published: July 2016

The most important problems regarding the regeneration of coppice are treated here. 1. The different means of regeneration a) by stump sprouts b) by suckers c) by seedlings 2. The factors which determine the formation of sprouts are: the species, the season of cutting, age and dimension of stumps and the site. 3. Conifer sprouts A study of the way and the conditions under which the different kinds of conifers are able to sprout. 4. Stump decay A study of the causes of stump decay and the way to prevent it. Finally several subjects for research are suggested in connection with the regeneration of coppice.