bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bifunctional Catalysts Based on Tungsten Hydrides Supported on Silicated Alumina for the Direct Production of 2,3‐Dimethylbutenes and Neohexene from Isobutene
Authors: Larabi Cherif , Garron Anthony , Rouge Pascal , Szeto Kai C. , Norsic Sébastien , De Mallmann Aimery , Merle Nicolas , Taoufik Mostafa 
Published: February 2017

AbstractWell‐defined bifunctional supported catalysts that comprise tungsten hydride moieties and Brønsted acid sites were prepared successfully. The catalysts showed outstanding activities and selectivities toward the formation of high‐value‐added products, 2,3‐dimethylbutenes and 3,3‐dimethylbutene, through a combination of the metathesis and dimerization of isobutene. The relationship between the physicochemical properties of the catalysts and their activities and selectivities indicated that isobutene conversion increased from 4 to 95 % as a function of the silica content of the silicated alumina (obtained from Sasol). Nevertheless, the selectivity toward branched hexenes showed a volcano‐shaped curve that presented a maximum for the catalyst with 5 wt % silica. Therefore, the control of the support acidity by the silica loading on alumina resulted in an increase of the selectivity toward neohexene.
Synergistic Effect of Flakes Containing Interconnected Nanoparticles and Conducting Graphene Additive to Qualify ZnMn2O4 as Potential Lithium‐Battery Anode
Authors: Sekhar Bongu Chandra , Packiyalakshmi Parameswaran , Kalaiselvi Nallathamby 
Published: February 2017

AbstractZnMn2O4 flakes, composed of interconnected nanoparticles were synthesized by using a hydrothermal technique and treated subsequently with nitrogen‐doped graphene (NG) to obtain a composite containing graphene sheets decorated with ZnMn2O4 nanoparticles. When explored as a lithium‐battery anode, ZnMn2O4/NG exhibits a superior electrochemical performance compared to a pristine ZnMn2O4 anode. Interestingly, the ZnMn2O4/NG composite anode displays a steady‐state reversible capacity of 1400 mAh g−1 at 100 mA g−1, which is higher than the theoretical capacity and the highest ever capacity achieved so far, with respect to the ZnMn2O4 electrode material. Furthermore, the nanocomposite anode shows a stable capacity of 790 mAh g−1 up to 1000 cycles and the corresponding coulombic efficiency is 99 % at 500 mA g−1, exhibiting excellent rate capability. The superior electrochemical performance of the ZnMn2O4/NG anode may be ascribed to the multiple synergistic advantages offered by NG, such as enhanced electrode conductivity, maintenance of structural integrity upon cycling, and the effective accommodation of volume changes during charging and discharging. Our results indicate that the synthesized ZnMn2O4/NG nanocomposite anode could be considered as a promising candidate for next‐generation high‐rate lithium‐ion‐battery applications.
Double‐Shelled TiO2 Hollow Spheres Assembled with TiO2 Nanosheets
Authors: Zhang Chao , Zhou Yuming , Zhang Yiwei , Zhao Shuo , Fang Jiasheng , Sheng Xiaoli , Zhang Tao , Zhang Hongxing 
Published: February 2017

AbstractHigh‐quality double‐shelled TiO2 hollow spheres (DHS‐Ti) assembled with TiO2 nanosheets have been synthesized for the first time through a simple hydrothermal treatment of sSiO2@TiO2 (TiO2‐coated solid SiO2 spheres). The double‐shelled structure shows a high BET surface area up to 417.6 m2 g−1. Anatase DHS‐Ti of high crystallinity can be obtained without structural collapse by calcination treatment. The effects of cetyl trimethylammonium bromide (CTAB) concentration, pH, and hydrothermal reaction temperature have also been investigated with a series of contrast experiments. A formation mechanism involving the in situ growth of amorphous TiO2 nanosheets followed by the redeposition of dissolved silica species is proposed. Lastly, the DHS‐Ti forming strategy can be extended as a general strategy to fabricate various morphological hollow nanostructures and double‐shelled Pt nanocatalysts by rationally selecting functional sSiO2 nanoparticles as core materials. This work could open up a new strategy for controllable synthesis of complex hollow structures and other functional materials.
HSO2+ Formation from Ion‐Molecule Reactions of SO2⋅+ with Water and Methane: Two Fast Reactions with Reverse Temperature‐Dependent Kinetic Trend
Authors: Cartoni Antonella , Catone Daniele , Bolognesi Paola , Satta Mauro , Markus Pal , Avaldi Lorenzo 
Published: February 2017

AbstractIn this work an experimental and theoretical study on the formation of HSO2+ ion from the SO2⋅++CH4 and SO2⋅++H2O ion–molecule reactions at different temperatures is reported. Tunable synchrotron radiation was used to produce the SO2⋅+ ion in excited ro‐vibrational levels of the ionic ground state X2A1 and mass spectrometry was employed to identify the product ions. Calculations in the frame of the density functional theory and variational transition state theory were combined to explore the dynamics of the reactions. The experimental results show that HSO2+ is the only product in both reactions. Its yield decreases monotonically with photon energy in the SO2⋅++H2O reaction, while it decreases at first and then increases in the SO2⋅++CH4 reaction. Theory confirms this trend by calculating the rate constants at different temperatures and explains the results by means of the polar, spin and charge effects as well as structural reorganization occurring in the reaction coordinate. The dynamic behavior observed in these two reactions is of general and fundamental interest. It can also provide some insights on the role of these reactions in astrochemistry as well as in their use as models for bond‐activation reactions.
A central mesencephalic reticular formation projection to medial rectus motoneurons supplying singly and multiply innervated extraocular muscle fibers
Authors: Bohlen Martin O. , Warren Susan , May Paul J. 
Published: February 2017

AbstractWe recently demonstrated a bilateral projection to the supraoculomotor area from the central mesencephalic reticular formation (cMRF), a region implicated in horizontal gaze changes. C‐group motoneurons, which supply multiply innervated fibers in the medial rectus muscle, are located within the primate supraoculomotor area, but their inputs and function are poorly understood. Here, we tested whether C‐group motoneurons in Macaca fascicularis monkeys receive a direct cMRF input by injecting this portion of the reticular formation with anterograde tracers in combination with injection of retrograde tracer into the medial rectus muscle. The results indicate that the cMRF provides a dense, bilateral projection to the region of the medial rectus C‐group motoneurons. Numerous close associations between labeled terminals and each multiply innervated fiber motoneuron were present. Within the oculomotor nucleus, a much sparser ipsilateral projection onto some of the A‐ and B‐ group medial rectus motoneurons that supply singly innervated fibers was observed. Ultrastructural analysis demonstrated a direct synaptic linkage between anterogradely labeled reticular terminals and retrogradely labeled medial rectus motoneurons in all three groups. These findings reinforce the notion that the cMRF is a critical hub for oculomotility by proving that it contains premotor neurons supplying horizontal extraocular muscle motoneurons. The differences between the cMRF input patterns for C‐group versus A‐ and B‐group motoneurons suggest the C‐group motoneurons serve a different oculomotor role than the others. The similar patterns of cMRF input to C‐group motoneurons and preganglionic Edinger‐Westphal motoneurons suggest that medial rectus C‐group motoneurons may play a role in accommodation‐related vergence.
On the benefits of the remote GPU virtualization mechanism: The rCUDA case
Authors: Silla Federico , Iserte Sergio , Reaño Carlos , Prades Javier 
Published: February 2017

SummaryGraphics processing units (GPUs) are being adopted in many computing facilities given their extraordinary computing power, which makes it possible to accelerate many general purpose applications from different domains. However, GPUs also present several side effects, such as increased acquisition costs as well as larger space requirements. They also require more powerful energy supplies. Furthermore, GPUs still consume some amount of energy while idle, and their utilization is usually low for most workloads. In a similar way to virtual machines, the use of virtual GPUs may address the aforementioned concerns. In this regard, the remote GPU virtualization mechanism allows an application being executed in a node of the cluster to transparently use the GPUs installed at other nodes. Moreover, this technique allows to share the GPUs present in the computing facility among the applications being executed in the cluster. In this way, several applications being executed in different (or the same) cluster nodes can share 1 or more GPUs located in other nodes of the cluster. Sharing GPUs should increase overall GPU utilization, thus reducing the negative impact of the side effects mentioned before. Reducing the total amount of GPUs installed in the cluster may also be possible. In this paper, we explore some of the benefits that remote GPU virtualization brings to clusters. For instance, this mechanism allows an application to use all the GPUs present in the computing facility. Another benefit of this technique is that cluster throughput, measured as jobs completed per time unit, is noticeably increased when this technique is used. In this regard, cluster throughput can be doubled for some workloads. Furthermore, in addition to increase overall GPU utilization, total energy consumption can be reduced up to 40%. This may be key in the context of exascale computing facilities, which present an important energy constraint. Other benefits are related to the cloud computing domain, where a GPU can be easily shared among several virtual machines. Finally, GPU migration (and therefore server consolidation) is one more benefit of this novel technique.
Energy‐efficient fuzzy control model for GPU‐accelerated packet classification
Authors: Li Guo , Zhang Dafang , Li Yanbiao , Zheng Jintao , Li Keqin 
Published: February 2017

SummaryAs a core component of many network infrastructures, packet classification requires matching packet headers against a series of predefined rules. Its performance determines, to some extent, how fast packets can be processed. There already exists many proposals, which optimize the throughput of packet classification, but few of them take power consumption into account. To meet the requirements of green network computing, this paper focuses on energy‐efficient solutions that provide reasonable throughput as well. Similar to recent advancements, the graphics processing unit (GPU) is adopted to accelerate rule matching. Then, inspired by the frequency‐variable energy‐consuming model for air conditioners, a fuzzy control–based energy efficiency optimizing model is proposed for GPU‐accelerated packet classification. As demonstrated in the evaluation experiments, when the GPU is in the idle status, the proposed model can save 10 W. In running status, the fuzzy control–based energy efficiency optimizing model can avoid GPU shutdown issue caused by GPU self‐protection mechanism when the GPU temperature rises to 95°C. Furthermore, by improving the resource configuration of GPU kernels according to the model, the overall energy efficiency is enhanced by up to 15.5%, while simultaneously keeping throughput at the same level.
Photocatalysis of a [2+2] Cycloaddition in Aqueous Solution Using DNA Three‐Way Junctions as Chiral PhotoDNAzymes
Authors: Gaß Nadine , Gebhard Julian , Wagenknecht Hans‐Achim 
Published: February 2017

AbstractThe front cover artwork is provided by the Wagenknecht group at KIT. The image shows a three‐dimensional model of the DNA three‐way junction with an internal benzophenone nucleotide in the photoreactive center that induces asymmetry during substrate conversion. Read the full text of the article at 10.1002/cptc.201600034.
Antinociceptive and Antihyperalgesic Activity of a Traditional Maya Herbal Preparation Composed of Pouteria Campechiana, Chrysophyllum Cainito, Citrus Limonum, and Annona Muricata
Authors: Déciga‐Campos Myrna , Ortiz‐Andrade Rolffy , Sanchez‐Recillas Amanda , Flores‐Guido José Salvador , Ramírez Camacho Mario A. 
Published: February 2017

ABSTRACT

Preclinical Research

The purpose of this work was to assess the antinociceptive and antihyperalgesic properties of an herbal preparation, composed of four vegetal species: Pouteria campechiana (P. campechiana), Chrysophyllum cainito (C. cainito), Citrus limonum (C. limonum), and Annona muricata (A. muricata), that is commonly used in combination (PCCA) in traditional Mayan medicine for the treatment of diabetes and pain. An ethanolic extract of PCCA was prepared at a ratio of 1:1:1:1 for each plant. The systemic antinociceptive effect of PCCA extract (50–600 mg/kg, p.o.) was dose‐dependent in the rat formalin (1%) producing 66% antinociceptive response at 400 mg/kg, p.o. A concentration‐dependent antinociceptive effect of the PCCA extract (20–160 mg/paw) was also demonstrated in the rat capsaicin (0.2%) test. The PCCA extract (100–400 mg/kg, p.o.) had antihyperalgesic effects in alloxan diabetic rats. These findings demonstrate the antinociceptive and antihyperalgesic effects of PCCA and supports the use of the plant extracts in Mayan folk medicine. Drug Dev Res 78 : 91‐97, 2017. © 2017 Wiley Periodicals, Inc.
A Novel Photo‐Induced Electrochemical Biosensing Method Based on Fluorescent Labeled Molecular Beacon
Authors: Zhang Panpan , Arken Gulijamal , Li Guixin , Guan Ming , Tian Shuge 
Published: February 2017

AbstractA novel photo‐induced electrochemical biosensing method has been developed based on fluorescence quenching effect and electrochemical method. In this sensing strategy, the molecular beacon probes labeled with methylene blue were immobilized on the gold nanoparticles modified gold electrode surface firstly; then dopamine was assembled on the electrode surface through electrostatic interaction with gold nanoparticles. Under the continuous illumination, the fluorescence of the methylene blue was quenched by the gold nanoparticles before hybridization; after hybridization with the complementary DNA, methylene blue was far away from the gold nanoparticles and the fluorescence recovered, and then singlet oxygen was generated in the photosensitive reaction of methylene blue in the presence of dissolved oxygen. Singlet oxygen reacted with dopamine, which resulted in the reduction of concentration of the dopamine on the electrode surface. The current of the dopamine on the electrode was used for the sensing of the conformational change of molecular beacon and hence for the detection of target DNA.
Uncertainties in modelling heat transfer in fire resistance tests: A case study of stone wool sandwich panels
Authors: Livkiss K. , Andres B. , Johansson N. , van Hees P. 
Published: February 2017

SummaryModelling fire performance of building fire barriers would allow optimising the design solutions before performing costly fire resistance tests and promote performance‐based fire safety engineering. Numerical heat conduction analysis is widely used for predicting the insulation capability of fire barriers. Heat conduction analysis uses material properties and boundary condition parameters as the input. The uncertainties in these input parameters result in a wide range of possible model outcomes. In this study, the output sensitivity of a heat conduction model to the uncertainties in the input parameters was investigated. The methodology was applied to stone wool core sandwich panels subjected to the ISO 834 standard fire resistance temperature/time curve. Realistic input parameter value distributions were applied based on material property measurements at site and data available in literature. A Monte Carlo approach and a functional analysis were used to analyse the results. Overall, the model is more sensitive to the boundary conditions than to the material thermal properties. Nevertheless, thermal conductivity can be identified as the most important individual input parameter.
TMEM16A/ANO1 suppression improves response to antibody‐mediated targeted therapy of EGFR and HER2/ERBB2
Authors: Kulkarni Sucheta , Bill Anke , Godse Neal R. , Khan Nayel I. , Kass Jason I. , Steehler Kevin , Kemp Carolyn , Davis Kara , Bertrand Carol A. , Vyas Avani R. , Holt Douglas E. , Grandis Jennifer R. , Gaither L Alex , Duvvuri Umamaheswar 
Published: February 2017

AbstractTMEM16A, a Ca2+‐activated Cl− channel, contributes to tumor growth in breast cancer and head and neck squamous cell carcinoma (HNSCC). Here, we investigated whether TMEM16A influences the response to EGFR/HER family‐targeting biological therapies. Inhibition of TMEM16A Cl− channel activity in breast cancer cells with HER2 amplification induced a loss of viability. Cells resistant to trastuzumab, a monoclonal antibody targeting HER2, showed an increase in TMEM16A expression and heightened sensitivity to Cl− channel inhibition. Treatment of HNSCC cells with cetuximab, a monoclonal antibody targeting EGFR, and simultaneous TMEM16A suppression led to a pronounced loss of viability. Biochemical analyses of cells subjected to TMEM16A inhibitors or expressing chloride‐deficient forms of TMEM16A provide further evidence that TMEM16A channel function may play a role in regulating EGFR/HER2 signaling. These data demonstrate that TMEM16A regulates EGFR and HER2 in growth and survival pathways. Furthermore, in the absence of TMEM16A cotargeting, tumor cells may acquire resistance to EGFR/HER inhibitors. Finally, targeting TMEM16A improves response to biological therapies targeting EGFR/HER family members.
Trace and rare earth element geochemistry of crude oils and their coexisting water from the Jiyuan Area of the Ordos Basin, N China
Authors: Zhao Yan , Liu Chi‐Yang , Niu Hai‐Qing , Zhao Xiao‐Chen , Zhang Dong‐Dong , Yang Di , Deng Hui 
Published: February 2017

The concentration of trace and rare earth elements in 22 crude oil and five oilfield water samples, collected from Triassic Yanchang Formation and Jurassic Yanan Formation reservoirs in the Jiyuan Area of Ordos Basin, N China, was determined using inductively coupled plasma mass spectrometry (ICP‐MS) for the first time. The oil samples were analysed to classify the oils into family and to determine the origin and depositional environment of organic matter that yield the oils using trace elements. The REE chondrite‐normalized distribution patterns of the crude oils show light rare earth element (LREE) enrichment and right‐oblique curves. These patterns could be divided into two distinct types that were consistent with that of the upper continental crust (UCC) and lower continental crust (LCC) characterizing by negative Eu anomalies and positive Eu anomalies, respectively. The REE concentrations in coexisting water samples are less than those in crude oils by a factor of ten. Cluster analysis also classified the oil samples from the Ordos Basin into two main groups. Integrated analysis of Co/Ni, V/Ni and V/ (V + Ni) values suggests that the organic matter have more terrigenous source input and the palaeoenvironment was anoxic and slightly oxic conditions. This study differs from previous studies by using trace element analyses of crude oils to constrain oil‐source rock correlation. The results show that most of the crude oils in north Jiyuan area were derived from Chang 7 mudstones while those from Hongde area may be contributed by Chang 7 oil shales. Copyright © 2017 John Wiley & Sons, Ltd.
Meta‐analysis comparing the safety of laparoscopic and open surgical approaches for suspected adnexal mass during the second trimester
Authors: Liu Yi‐Xuan , Zhang Yang , Huang Jin‐Feng , Wang Li 
Published: February 2017

AbstractBackgroundThe safety of laparoscopic surgery during the second trimester of pregnancy remains a controversial subject.ObjectivesTo compare the safety of laparoscopic surgery and laparotomy for suspected adnexal mass during the second trimester.Search strategyArticles published in any language prior to April 31, 2016, were retrieved from PubMed, Scopus, EMBSCO, and the Cochrane Library using keywords including pregnant, adnexal mass, laparoscopy, laparotomy, pregnancy outcomes, and surgical outcomes.Selection criteriaRandomized and non‐randomized controlled trials reporting at least one obstetric or surgical outcome were included if they compared laparoscopic surgery and laparotomy for adnexal masses during the second trimester.Data collection and analysisData were independently extracted by two reviewers. Homogeneous data were pooled using a fixed effects model and heterogeneous data were qualitatively analyzed.Main resultsFour comparative effectiveness studies including a total of 240 patients were identified. Laparoscopic surgery was associated with a reduced risk of post‐operative adverse events (relative risk 0.20, 95% confidence interval 0.06–0.72); no difference was recorded in the risk of post‐operative spontaneous abortion (P=0.26) or threatened spontaneous abortion (P=0.13).ConclusionsLaparoscopic surgery could be preferable to laparotomy for suspected adnexal mass during the second trimester of pregnancy.
Factors associated with maternal mortality among patients meeting criteria of severe maternal morbidity and near miss
Authors: Lima Hesly M.P. , Carvalho Francisco Herlânio C. , Feitosa Francisco Edson L. , Nunes George C. 
Published: February 2017

AbstractObjectiveTo evaluate factors associated with maternal death among women experiencing life‐threatening conditions during pregnancy, childbirth, or within 42 days of termination of pregnancy.MethodsA secondary analysis of data prospectively collected in a Brazilian multicenter cross‐sectional study between July 2009 and June 2010 was conducted. Women were identified who delivered at a hospital in Ceará and who had potentially life‐threatening conditions. Stepwise logistic regression was used to identify factors associated with maternal death.ResultsOverall, 941 women were identified and 11 died. Among criteria for severe maternal morbidity, eclampsia (adjusted odds ratio [aOR] 203.70, 95% CI 5.03 to 8254.20; P=0.005) and intensive care unit (ICU) admission (aOR 69.30, 95% CI 6.63–724.26; P<0.001) were risk factors for progression to death, whereas use of magnesium sulfate (aOR 0.002, 95% CI <0.01–0.11; P=0.002) was a protective factor. Meeting near‐miss criteria other than survival (aOR 5.96, 95% CI 1.69–20.98; P=0.005) was associated with maternal death. Of criteria for near miss, management criteria were most strongly associated with maternal death: all 11 women who died met some management criteria.ConclusionAmong WHO's criteria for severe maternal morbidity and near miss, eclampsia, low oxygen saturation, ICU admission, intubation, mechanical ventilation, and cardiopulmonary resuscitation were most associated with maternal death. Use of magnesium sulfate was a protective factor.