bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decision Making in a Data-Poor Environment: Management of Brain Metastases From Testicular and Extragonadal Germ Cell Tumors
Authors: Gilligan Timothy 
Published: December 2015

The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management challenges, a review of the relevant literature, and a summary of the authors' suggested management approaches. The goal of this series is to help readers better understand how to apply the results of key studies, including those published in Journal of Clinical Oncology, to patients seen in their own clinical practice. A 32-year-old man with a history of a mixed germ cell tumor of the testis presented with acute-onset, right-sided weakness and numbness. His previous treatment included orchiectomy, which revealed a 5-cm tumor that was 95% yolk sac tumor and 5% embryonal carcinoma, and retroperitoneal lymph node dissection for clinical stage I disease in January 2010, which revealed no nodal metastases. Starting in June 2010, he was treated with four cycles of etoposide and cisplatin for pulmonary and thoracic lymph node metastases and a rising serum alpha-fetoprotein (AFP) level. He subsequently received four cycles of paclitaxel, ifosfamide, and cisplatin for relapse in the lungs and mediastinal nodes with a rising AFP level starting in January 2011. He reported having a 2-week history of intermittent headaches in December 2011, when he presented with acute-onset, right-sided weakness and numbness. Computed tomographs of the head was obtained and demonstrated a left parietal intracranial hemorrhage without midline shift or hydrocephalus. Brain magnetic resonance imaging (MRI) showed a complex, 4.5-cm mass consistent with a hemorrhagic metastasis. His serum AFP level was elevated at 47 ng/mL. The patient became progressively obtunded and underwent emergency surgical decompression and resection of the tumor. Histopathologic evaluation of the resected tissue showed metastatic germ cell tumor predominantly consisting of a yolk sac element ( Fig 1 ). His AFP level declined rapidly after resection, and computed tomography of the chest, abdomen, and pelvis showed no evidence of metastatic disease. However, 2 weeks later, his AFP level rose again, and repeat MRI of the brain showed a 3-cm mass in the left mesial parietal lobe adjacent to the resection site. He started treatment with filgrastim to facilitate collection of circulating hematopoietic stem cells. Several days later, after apheresis, he received his first of two cycles of high-dose carboplatin 700 mg/m2 on days −5, −4, and −3 and etoposide 750 mg/m2 on days −5, −4, and −3. The patient had a complete response to high-dose chemotherapy and no major acute complications. His cancer remains in complete remission 3 years later without additional treatment. His three lines of chemotherapy left him with chronic peripheral neuropathy.
The TOUCH program and natalizumab: Fundamental flaw in patient protection
Authors: Avasarala Jagannadha 
Published: December 2015

Many drugs have been approved by the Food and Drug Administration (FDA) since 1993 for treatment of relapsing forms of multiple sclerosis (MS). One such drug is natalizumab (Tysabri, Biogen Idec and Elan pharmaceuticals) which has enjoyed great success in the management of MS since its re-introduction in 2006. One of the complications of using natalizumab is the risk of development of progressive multifocal leukoencephalopathy (PML). To mitigate the risk of PML development, Biogen Idec initiated the TOUCH program – this strategy helps monitor the disease. Clinical vigilance is remains key in the early diagnosis of PML but serological testing for the John Cunningham Virus Antibody (JCV) helps with risk stratification of PML. However, some physicians do not test for the JCV Ab and since they are not required to send such data to the company or inform the patient, one red flag for suspicion of PML is lost particularly if the patient is asymptomatic. This undercuts the premise of the TOUCH program. In an ideal world, reporting JCV Ab status should be made mandatory since that ensures a basic tenet of the program is met – to identify patients at increased risk of developing PML and make appropriate recommendations based on that finding. Lack of requirement of reporting of this vital finding opens the door for uncertainty in assessment of risk PML development and everyone remains in the dark till it may be too late. This is unacceptable when the company created the TOUCH program specifically with intent to track PML risk in patients on natalizumab. It makes no scientific sense to let the drug be used without setting stringent criteria given the possibility of PML development.
First Record Of Clytra Laeviuscula Ratzeburg As Potential Insect Pest Of Energy Willow (Salix Viminalis L.) In Ukraine
Authors: Stefanovska Tatyana , Lewis Edwin , Pidlisnyuk Valentina , Smyrnykh Oleg 
Published: December 2015

Abstract
Cultivation of short rotation coppice energy willow (SRC EW), Salix viminalis L., has a great potential in Ukraine as a source of biomass for biofuel production. Commercial production of this species was recently initiated in the country. The growing of SRC EW in Western and Northern Europe for a long time showed that leaf beetles (Coleoptera: Chrysomelidae) are key pests causing significant biomass reduction. However, data about the pest complex for energy willow growing in Ukraine is not available. Our three-year experiment in Poltava region, Ukraine showed that foliar damage caused by Clytra laeviuscula Ratzeburg (Coleoptera: Chrysomelidae) occurred at energy willow plantations in the second year of production, which could have an effect on commercial production. Accordingly, information about seasonal activity, population dynamics, host range and the role of natural enemies in pest regulation are requested for developing pest control program.
Supplemento papirologico alle recenti edizioni dei Milesii. Praesocratica Herculanensia VIII
Authors: Vassallo Christian 
Published: December 2015

AbstractThis paper provides a complete collection of the papyrological sources concerning the Milesians. Apart from some texts which do not appear in the Corpus dei Papiri Filosofici Greci e Latini (CPF), this collection also takes into account some Herculanean testimonia to Thales, Anaximander, and Anaximenes which have been forgotten in both the old and most recent editions of these pre-Socratic philosophers. An appendix deals with the alleged references to the Milesians in Book 11 of Epicurus’ On Nature.
Classical and Biblical Culture in Late Antique Egypt Some Notes
Authors: Berkes Lajos 
Published: December 2015

AbstractThis article discusses P.Gen. 4.159, a hexametric enkomion from the 6th c. AD, an allusion to Job in the petition, P.Cair. Masp. 1.67002 (567, Aphrodito) and the first attestation of the word prosynaxis in papyri (SB 18.13272).
Pathological Spinal Fracture Due to Metastasis of Mucinous Breast Carcinoma
Authors: Bremmers Martins , Stukens Janis , Bergs Gvido Janis , Jakovlevs Arvids , Vanags Andrejs , Strumfa Ilze 
Published: December 2015

Summary
Spinal metastases represent a common event in oncological patient. Such tumour spread can reduce the life quality significantly due to pain, pathological fracture and spinal cord compression. Breast cancer is among the most common primary sources. However, certain histological types of breast cancer, including mucinous carcinoma, are known for less aggressive behaviour. Here we present a clinical case of 44-year-old female affected by mucinous carcinoma in left mammary gland, resulting in regional lymph node involvement and multiple remote metastases in left lung and Th7 vertebra. This case is notable as mucinous breast carcinoma rarely develops at such age and infrequently shows wide metastatic spread.
Molecular Perspective of Radionuclides Separation by Nanoporous Graphene Oxide Membrane
Authors: Arabieh Masoud , Mahmood Fatemi S. , Sepehrian Hamid 
Published: December 2015

Abstract
Graphene-derived membranes has gained much interest recently due to its promising potential in filtration and separation applications. Molecular Sieving phenomena of gas molecules in the interlayer of graphene oxide nanopore have been investigated using molecular dynamic (MD) simulation. We explore I-129 gas radionuclides sequestration from natural air in nanoporous graphene oxide membranes in which different sizes and geometries of pores were modeled on the graphene oxide sheet. In the present work, mean-squared displacement (MSD), diffusion, flow of gas and the number of crossed gas molecules through graphene oxide nanopore membrane have been calculated and the results showed, selective proper nanopores in graphene oxide membrane could dramatically improve separation. The aim of this paper is to show that for the well-defined pore size called P-12, it is possible to separate I-129 from a gas mixture containing I-129, O2 and N2. The results would be benefited by the oil industry and others.
Schelling und der Selbstrepräsentationalismus über phänomenales Bewusstsein
Authors: Lang Stefan 
Published: December 2015

Abstract
This paper explores Schelling’s theory of phenomenal consciousness in the System of Transcendental Idealism. It is shown that Schelling’s description and explanation of phenomenal consciousness is in accord with contemporary self-representationalist accounts of phenomenal consciousness. Thus, it is argued that Schelling develops a self-representationalist approach of phenomenal consciousness. Furthermore, it is demonstrated on the basis of Schelling’s account that analytic self-representationalism fails to completely explain phenomenal consciousness. Finally, however, a fundamental critique of Schelling’s theory of phenomenal consciousness is presented. Thus the central theses of the paper are, on the one hand, that Schelling is of systematic importance for contemporary debates, on the other hand, that his account is not convincing.
Ästhetische Objektivität
Authors: Feige Daniel Martin 
Published: December 2015

Abstract
The question posed in this paper is in what sense we should say that our judgments about works of art can claim to be objective. It draws upon recent discussions in analytical aesthetics on the one hand and on the work of Hegel, Gadamer and McDowell on the other. The aim of the paper is to argue for the possibility of an objectivistic understanding of judgments on works of art. It does so by trying to render the foundations of subjective accounts of such judgments problematic and by trying to show that the difference between objective and mere intersubjective claims of judgments isn’t a valid difference at all.
Der Einfluss des Darwinismus auf Dewey
Authors: Särkelä Arvi 
Published: December 2015

Abstract
This article aims at developing an account of John Dewey’s empirical naturalism by focusing on what he regards as “Darwin’s influence on philosophy.” If Dewey’s lifelong engagement with Darwinist themes and arguments is taken into consideration, it becomes clear that Darwinism not only motivates him to drop substantialist assumptions about nature and experience and to challenge the relationalist attitude at the root of most of modern science, but also to opt for a processualist disposition already at work in Darwin’s On the Origin of Species. What results is not a departure from all metaphysical speculation, but the hypothesis of a naturalist metaphysics that can do justice to what is implied in the Darwinian turn in science.
Zwischen Materialität und ‘Second Space’
Authors: Andrisević Andreja , Lukas Wolfgang , Wessel Ivo 
Published: December 2015

AbstractThe exhibition on the complete works of Paul Wühr in the Bibliotheca Reiner Speck (9.11.2014-2.2.2015, Cologne) combined material exhibition strategies with digital presentation culture. The breaking of standards and taboos, transgression of genres and interand intratextuality of the oeuvre were presented both by haptic exhibits in showcases, as well as by their virtual representation within an application on tablet computers. Different offers of sorting, filtering and hyperlinking within the mobile app enabled it to generate multiple secondary orders beyond the static physical order, and opened the exhibition structure towards interactivity.
Die Sammlung Eero Salmelainen
Authors: Bleckwenn Helga , Kauppala Pekka 
Published: December 2015

ZusammenfassungIm deutschen Sprach- und Rezeptionsraum ist der Erzahler Erik Rudbeck (1830-67) nicht mehr bekannt, wahrend in Finnland seine Marchensammlung unter dem Pseudonym Eero Salmelainen noch aufgelegt und gelesen wird. Darum sollen sein Leben und Werk hier vorgestellt werden. Daruber hinaus ist zu fragen, wie er derart in Vergessenheit geraten konnte. Eine Erklarung bieten die komplizierten Fraktionierungen von Schweden und Finnen gegenuber Rusland in der finnlandischen Nationalbewegung wie auch der rufschadigende Vorwurf des Plagiats gegen Rudbecks Lizentiatsarbeit und spater die sehr verdienstvolle, doch eher quellen- und motivgeschichtlich orientierte finnische Forschung, die Salmelainens Leistung als Sammler und Forscher nicht eigentlich gewurdigt hat. Er ware als finnischer Vertreter einer Volkspoesie in der Tradition der Bruder Grimm zu sehen.
Automobile Rechtfertigungen
Authors: Geuenich Michael 
Published: December 2015

ZusammenfassungAnhand von Beiträgen eines journalistischen Schreibaufrufs geht dieser Beitrag rhetorischen Mustern und Semantiken der Legitimation der Autonutzung in Alltagserzählungen nach. Autogeschichten sind in erster Linie Rechtfertigungsgeschichten, das Erzählen befriedet die Diskrepanz von (Umwelt-)Wissen und Handeln. Den Legitimationsfiguren wohnt dabei zumeist ein vergleichendes Moment inne, das die Rationalität der Fahrenden betonen soll. Ein weiteres bedeutsames Legitimationsmuster ist die anthropomorphisierende Rede vom Automobil, die Autobesitz und -nutzung mit Verweis auf die quasi-menschliche Beziehung rechtfertigt.
EN ENSOM NORSK GRAV I POZNAŃ. ET POSTSKRIPTUM TIL THE GREAT ESCAPE
Authors: Lange Tadeusz W. 
Published: December 2015

Abstract
The article is an account of the life and death of Halldor Espelid, a young Norwegian RAF pilot born in Bergen, trained at “Little Norway” in Canada, shot down over occupied France, put in the POW camp for airmen in Sagan (now Żagań in Poland), arrested near Flensburg while taking part in the so-called Great Escape, and murdered at the age of 24 by the Kiel Gestapo. His body was cremated, his ashes buried at Sagan and later moved to the Old Garrison Cemetery in Poznań, Poland, together with the remains of 47 other participants of the famous Great Escape murdered at Hitler’s personal order.
Selected Properties Of Geopolymers With Different Portions Of Ground Fly-Ash
Authors: Želinková Miroslava 
Published: December 2015

Abstract
Geopolymers are polymeric materials resulting from the polycondensation reaction of alumino-silicate materials in a strongly alkaline environment. In consequence, stable polymeric networks of aluminosilicates are formed. The binding potential of FA (fly ash) amorphous component can also be “activated” by mechanical activation, which unfolds new possibilities of FA utilization. Mechanical activation, such as the method, which can improve FA reactivity, is often applied for different applications for geopolymers based on ground fly ash. This paper presents possibilities of preparation of geopolymer mixtures based on modified (ground) FA (TEKO – produced by the Heating plant Kosice), which was used in varying percentages to unground (original) FA. The particle size of the original unground FA (PVT) was 84.7μm and particle size of the ground FA (T60S1) was 52.8μm. Properties to be evaluated were selected from the expected application point of view – protective coating of concrete. Next properties of geopolymer mixtures after 28 days of hardening were tested and evaluated: dry density, absorptivity, capillarity, compressive and flexural strength.
„Abgedrehte Kupferwaren‟: Kriegsmaterialexporte der schweizerischen Uhren-, Metall- und Maschinenindustrie im Ersten Weltkrieg
Authors: Rossfeld Roman 
Published: December 2015

Abstract
During the First World War, warfare became more totalitarian and was backed by an economic conflict waged with increasingly harsh methods. In the combatant nations munitions rapidly became an essential “raw material”, with the increasing demand being met either by the expanding domestic arms industry or by munitions imports from neutral countries. The Swiss watch, metal and engineering industries enjoyed a strong international reputation and had a strong focus on exports: by the end of 1914 they began manufacturing precision detonators for artillery projectiles, and rising quantities of these products were sold to both sides. This paper examines what volume Swiss munitions exports assumed during the First World War, how this was compatible with Swiss neutrality and looks at the arguments used to criticise or justify this trade over the course of the war.
Reflections on the next generation of hemostasis instrumentation. A glimpse into the future?
Authors: Lippi Giuseppe , Bovo Chiara , Favaloro Emmanuel J. 
Published: December 2015

Abstract
Hemostasis testing is conventionally referred to as performance of in vitro diagnostic tests for screening, diagnosis and therapeutic management of patients with either bleeding or thrombotic disorders. The ongoing revolution of diagnostic testing, squeezed between reduced funding and increasing volumes, carries notable implications in the way laboratory resources are organized and coagulation tests delivered. It is therefore predictable that the newer generation of hemostasis analyzers may be designed to face these emerging needs whilst maintaining a high degree in the quality of testing. In this opinion paper, we aim to discuss some concepts of redesigning coagulation analyzers in consideration of the most important aspects of the preanalytical, analytical and postanalytical phases in hemostasis testing.
Role Of Computational Simulations In The Design Of Piston Rings
Authors: Novotný Pavel , Raffai Peter , Dlugoš Jozef , Maršálek Ondřej , Knotek Jiří 
Published: December 2015

Abstract
The paper presents computational approaches using modern strategies for a dynamic piston ring solution as a fluid structural problem. Computational model outputs can be used to understand design parameter influences on defined results of a primarily integral character. Piston ring dynamics incorporates mixed lubrication conditions, the influence of surface roughness on oil film lubrication, the influence of ring movement on gas dynamics, oil film formulation on a cylinder liner and other significant influences. The solution results are presented for several parameters of SI engine piston rings.
Selection Of Analytical Computational Model Of Contact Pressure
Authors: Maršálek Ondřej , Vopařil Jan , Raffai Peter , Novotný Pavel 
Published: December 2015

Abstract
This paper presents a comparison of two contact pressure calculation methods between two real rough surfaces: a calculation based on FEM (Finite Element Method) using commercial software tool ANSYS and a calculation based on FDM (Finite Difference Method) using analytical functions implemented in programing tool MATLAB. This comparison, lately, leads to the selection of the most appropriate analytical contact model useful for time-effective and precise contact pressure determination. Surface data for numerical simulations are obtained by optical profilometry. For the case of the modelling process of 3D FEM models of rough surfaces the description of their building is included in this article. Furthermore, this paper discusses all challenges connected with the convergence of such simulations and essential post-processing of FEM simulation results, together with their comparison, along the results obtained by user-written MATLAB functions.
Coopetition Effect Determinants: Competitor’s Size, Geographical Scope, Market and Technological Positions
Authors: Cygler Joanna , Dębkowska Katarzyna 
Published: December 2015

Abstract

Background and Goal: The article is aimed at conducting an empirical analysis of the value and significance of coopetitors’ attributes thanks to which coopetition, which is a combination of cooperation and competition between competitors, generates a substantial corporate profit. Four major competitors’ attributes have been analysed: its size, geographical scope, market and technological position. The research also includes the Porter’s value chain.

Design/ Methodology/Approach: The survey has been conducted on a sample of 235 high- tech companies operating in Poland and involved in coopetition. The sample is representative. The data have been collected at interviews with company top executives or owners. The research applies the method of classification trees, which, thanks to diagrams, sequentially divides the examined data space into classes (spaces) of similar properties. The assessment of the effect of coopetition, including its variants, made by the examined company served as a dependent qualitative variable. Four coopetitor’s attributes and their variants were assumed as explanatory variables (predictors) affecting the assessment of cooperation.

Results: The results of research indicated the necessity for an accurate competitor’s profile selection. The significance of each of the four attributes may be different depending on the undertaken areas of cooperation with a competitor. The value of all the attributes of competitors is also diverse depending on the area of cooperation. A selected competitor’s profile with regard to the four analysed attributes may become a stimulant to generate benefits in one area, while in another area it may become an inhibitor.

Conclusions: So far, the selection of a coopetition partner has been treated universally, without scrutinizing on some specific needs in relation to the area of cooperation. The selection of an appropriate coopetitor’s profile will allow for the cost reduction in search of appropriate candidates for cooperation and in relations management.
Die Rolle der russischen Sprache in der Gegenwart
Authors: Scharonov Igor 
Published: December 2015

Abstract
This article is devoted to the functioning of Russian language in the modern world and raises a few issues: What are the regions of Russian diasporas nowadays? Under what conditions can Russian language survive in the foreign countries? How does Russian language change in its mother country and outside? It is also under discussion how language norms transform in modern Russian. It is stated that liberalization in lexical and register choice is opposed to the requirements of grammatical accuracy. Grammar is still considered as a marker of good education and culture of a person.
A new species of Peyrierocoris Chłond & Junkiert, 2010 (Hemiptera: Heteroptera: Reduviidae: Harpactorinae) from southern Madagascar
Authors: Chłond Dominik 
Published: December 2015

Abstract
Peyrierocoris (Sicardicoris) wojciechowskii sp. n. is described. The dorsal habitus and characters of the female genitalia are illustrated with four figures. A key to the subgenera and species of Peyrierocoris as well as a distribution map are given.
Chemical and physiological changes caused by aphids feeding on their host plants
Authors: Cichocka Elżbieta , Goszczyński Wojciech , Lubiarz Magdalena 
Published: December 2015

AbstractWe present significant information about damage caused to plants by the feeding of piercing–sucking insects, based on the example of aphids. Research concerning the impact of aphids on their host plants was already being carried out in the 1950s in the 20thcentury, but it is still being undertaken as it is very important. Aphid feeding causes deformation of plant tissues, disorders in plant metabolism and changes in the amount of various compounds in plant tissues. Plant viruses are transmitted in aphid saliva.