bluuebunny/crossref_metadata_2025_split huggingface dataset:
Where do parties interact? Issue engagement in press releases and tweets
Authors: IVANUSCH CHRISTOPH 
Published: October 2024

AbstractTo what extent political parties engage in debates about the same issues and how they respond to each other is highly relevant to democratic processes. Existing research on issue engagement has uncovered several interesting patterns and factors, but has neglected one important feature of contemporary democracies: nowadays, political actors have a wide range of communication channels at their disposal with the use of ‘newer’ forms of political communication (e.g., social media) potentially transforming discursive power relations between political actors. However, it remains largely unclear whether the extent and nature of issue engagement varies between more ‘traditional’ and ‘newer’ forms of political communication. To fill this gap, I apply unsupervised topic modelling to press releases and tweets from political parties in Austria, Germany and Switzerland (January 2019–September 2021). The statistical analysis shows substantial differences in issue engagement between political parties in press releases and on Twitter, now X. First, I find a higher likelihood of issue engagement between parties in tweets. Second, Twitter appears to moderate the influence of party‐level factors on issue engagement compared to press releases. The results show that for issue engagement in tweets, the importance of party size is smaller and the role of government parties is larger than in press releases, while the role of ideological distance does not seem to change. These findings add important insights to our understanding of the potential transformative effect of new communication technologies on party competition and political discourse.
Medicaid managed care restrictions on medications for the treatment of opioid use disorder
Authors: Stewart Maureen T. , Andrews Christina M. , Feltus Sage R. , Hodgkin Dominic , Horgan Constance M. , Thomas Cindy Parks , Nong Thuong 
Published: October 2024

AbstractObjectiveTo examine whether Medicaid managed care plan (MCP) utilization management policies for buprenorphine–naloxone and injectable naltrexone are related to key state Medicaid program policy decisions.Data Sources and Study SettingWe abstracted data on state Medicaid regulatory and policy information from publicly available sources and publicly available insurance benefit documentation from all 241 Medicaid MCPs operating in 2021.Study DesignIn this cross‐sectional study, we used bivariate and multivariate analyses to examine whether Medicaid MCP prior authorization and quantity limits on receipt of buprenorphine and injectable naltrexone were associated with key state Medicaid choices to leverage federal funds to expand coverage and eligibility (Medicaid expansion, 1115 waivers) and to regulate Medicaid MCPs (uniform preferred drug lists, medical loss ratio remittance). Models were adjusted for MCP characteristics, including profit status, behavioral health contracting arrangement, National Committee for Quality Assurance accreditation, size, market share, and state opioid overdose death rates. Average marginal effects (AME) were reported.Principal FindingsUtilization management was common among MCPs, and restrictions were more commonly applied to buprenorphine than injectable naltrexone, despite its higher cost. States that required MCPs to comply with utilization management policies stipulated in a uniform preferred drug list were more likely to require prior authorization for buprenorphine (AME: 0.29, 95% CI: 0.15–0.42) and injectable naltrexone (AME: 0.25, 95% CI: 0.12–0.38). MCPs in states that required plans to pay back earnings above a certain threshold were less likely to require prior authorization for buprenorphine (AME: −0.30, 95% CI: −0.43 to −0.18).ConclusionsRestrictions on medications for opioid use disorder are widespread among MCPs and vary by medication. State Medicaid regulatory and policy characteristics were strongly linked to MCPs' utilization management approaches. State Medicaid policy and contracting approaches may be levers to eliminate utilization management restrictions on medications for opioid use disorder.
The drivers of sustainable homeownership
Authors: Liu Liyi 
Published: October 2024

AbstractThis article introduces a novel measure of homeownership sustainability—homeownership longevity—and examines patterns of sustainable homeownership across multiple mortgage characteristics from 2012 onward, using a unique and nationally representative data set of first‐time homeowners, the National Mortgage Database borrower sample. Importantly, the unit of observation is the individual borrower and the data track how long each borrower remains a homeowner throughout the sample period. The results show that first‐time homebuyers have remained homeowners at high rates since 2012 with over 60% maintaining homeownership throughout the entire sample period. Although there are statistically significant differences in expected homeownership longevity by loan origination characteristics, the absolute magnitudes of these differences are small. Notably, the disparity among racial and ethnic groups in terms of homeownership longevity is small. The high rates and relative uniformity of homeownership longevity for this population suggest that self‐selection into homeownership and existing underwriting standards have allocated mortgage credit to households highly likely to maintain homeownership.
Physical, textural, and sensory characteristics of gluten‐free cupcakes developed with native and modified by hydrothermal treatment green plantain flours
Authors: Mendes Bruna de Andrade Braga , Almeida Matheus Ferreira , Silva Gabriela Leite , Amparo dos Anjos Dioneire , Fontan Gabrielle Cardoso Reis , Rebouças São José Alcebíades , Veloso Cristiane Martins 
Published: October 2024

AbstractGluten‐free diets are characterized by lower nutritional quality. The use of green plantain flour in gluten‐free formulations appears as an alternative to overcome this deficiency, considering that green plantains have a relevant content of bioactive compounds, dietary fiber, including resistant starch. The objective of this work was to evaluate the effect of the addition of native and modified by hydrothermal treatment green plantain whole flours in the form of gluten‐free cupcakes. The density, yield, and microstructure of the dough, specific volume (SV), height, crumb analysis, color, texture, and sensory acceptability of the cupcakes were evaluated. Partial replacement (40%) of rice flour by native and modified flours produced darker, redder cupcakes, less yellowish and with less color intensity. Sensory analysis revealed higher acceptance for cupcakes with native and modified flours, compared to the control, for appearance, flavor, texture, aroma, and overall acceptance. The native flour was the most viable option, as the cupcake produced with it showed the best values for hardness and chewiness, without changing elasticity and SV, in addition to superior sensory acceptance than the control and similar to cupcakes with other modified flours.Practical ApplicationPursuing to meet the market demand for gluten‐free products, with the cake being one of the most requested products in this market, and taking in account that green banana, from different cultivars, has gained interest for the production of flours. The production of flour and bakery products is of great interest to the food industry, not only because of its flavor and properties but also due to the economic and sustainable viability of producing whole green plantain flour with the potential for application, promoting diversification and innovation in the gluten‐free functional products market.
KIFC3 promotes the progression of non–small cell lung cancer cells through the PI3K/Akt pathway
Authors: Mu Yu , Liu Haoxiang , Luo Anni , Zhang Qingxiang 
Published: October 2024

AbstractBackgroundKinesin family member C3 (KIFC3), as reported, plays important roles in several tumor types. Nevertheless, it is unknown whether KIFC3 has effects on non–small cell lung cancer (NSCLC) development.Materials and methodsKIFC3 expression was detected by RT‐PCR, and its correlation with prognosis was analyzed by GEPIA website. Small interfering RNA against KIFC3 were adopted for modulating KIFC3 expression in NSCLC cells. KIFC3 effects on NSCLC cell proliferation were determined using the MTT and clone formation assay. Matrigel invasion and wound healing assays were adopted for measuring the invasion and migration capability of NSCLC cells. Western blot was applied for measuring the levels of proteins associated with the phosphatidylinositol‐3‐kinase/protein kinase B (PI3K/Akt) pathway in NSCLC cells.ResultsKIFC3 was markedly increased in NSCLC samples and cells. KIFC3 knockdown suppressed the proliferation, invasion, and migration in NSCLC. Mechanically, KIFC3 silencing suppressed NSCLC progression through inhibiting the PI3K/Akt pathway.ConclusionsKIFC3 lack suppressed the proliferation, invasion, and migration which works, at least partially, by the PI3K/Akt pathway. These findings suggest that targeting KIFC3 via the PI3K/Akt pathway may offer a novel therapeutic strategy for NSCLC.
The effect of addback statutes on CEO compensation
Authors: Hrazdil Karel , Lobo Gerald , Zhang Ray , Zhang Weiji 
Published: October 2024

AbstractExploiting the adoption of addback statutes, which occurred at different times, as exogenous shocks to corporate taxable income, we examine the effect of tax policy changes on the compensation of chief executive officers (CEOs). We provide evidence that CEOs of firms headquartered in states affected by addback statutes experienced a decrease in total compensation; the decrease is stronger for firms with higher intangibles and asset replacement costs relative to book values, and weaker for firms whose CEOs are more powerful. Our results have important implications for policy‐makers who strive to combat pay inequality and managerial myopia through tax laws.
Development and validation of nomogram for predicting the cancer‐specific survival among patients aged 80 and above with early‐stage non‐small cell lung cancer
Authors: Guo Qiang , He Yuan , Chen Shai , Hu Sheng , Wang Silin , Su Lang , Zhang Wenxiong , Xu Jianjun , Wei Yiping , Luo Guiping 
Published: October 2024

AbstractBackgroundThe use of nomograms in predicting the prognosis of early‐stage non‐small cell lung cancer (NSCLC), particularly in elderly patients, is not widespread. A validated prognostic model specifically for NSCLC patients over 80 years old holds promising potential for clinical application in forecasting patient outcomes.MethodsThe prognostic value of various factors for NSCLC patients aged 80 and above was evaluated using data from the Surveillance, Epidemiology, and End Results (SEER) database (2010–2017). Kaplan–Meier (KM) curves, Cox proportional hazards regression models, and nomogram were utilized to evaluate the impact of each factor on cancer‐specific survival (CSS).ResultsA cohort comprising 7045 individuals was selected for inclusion in the analysis. Through rigorous statistical analysis, 10 independent prognostic factors were identified and incorporated into the nomogram. The nomogram's receiver operating characteristic (ROC) curve area under the curve (AUC) was higher than that of the AJCC 7th edition TNM staging system's predicted CSS (0.744 versus 0.602), establishing the superior prognostic value of the nomogram.ConclusionsWe have successfully created a highly accurate and discriminative nomogram that enables oncologists to predict the survival outcome of each individual patient with I/II NSCLC who is 80 years or older.
Migrant placemaking as a response to governing through mobility‐making: An ethnic enclave and a digital community in South Korea
Authors: Shin HaeRan , Gutierrez Cassandra 
Published: October 2024

AbstractThis paper examines migrant placemaking in South Korea as a proactive response to governing power that works through making (im)mobilities. Unlike previous discussions that have viewed migrants' empowerment in political activities and identity‐related in a particular type of enclaves, this study sees migrant placemaking as a proactive response to governing through mobilities and comprehensively embraces various types of placemaking in South Korea. Based on mix‐up of various qualitative research methods, this study documents the migrant placemaking practices over time of two representative and quite different migrant groups: Chosǒnjok's enclave in Kuro‐Taerim area of Seoul and Latin Americans' digital communities. The former represents a big migrant group's physical and discursive migrant placemaking. Chosǒnjok migrants struggled with their stigmatised images and mistrust towards both China and Korea. The latter represents a small migrant group's digital placemaking. Latin American migrants were left without much knowledge about and recognition from the Korean society. We demonstrate how in seeking a community for themselves they adapt their environment, thereby empowering themselves. In demonstrating the interrelation of migrant placemaking and governing power, this study contributes to the understanding of the circuits of power, mobility and place in the case of migrants in South Korea.
A ‘Back Door’ Exploration of Social Problems in Comic Strip Dialogues With Marginalized Children
Authors: Røkkum Nina Helen Aas , Serbati Sara 
Published: October 2024

ABSTRACTBased on 35 comic strip dialogues with marginalized children in Italy, Norway and Slovenia, as well as three individual interviews with Italian practitioners, this article introduces a methodological approach that offers a ‘back door’ for exploring social problems embedded in the everyday lives of children. The analysis demonstrates the importance of adopting an everyday life perspective as an analytical strategy in conversations with children in marginalized life situations. This means shifting the focus away from solely examining risk factors and instead promoting a contextual understanding of risk, with an emphasis on amplifying the diverse voices of children.
Chromosome 8p Syndromes Clinical Presentation and Management Guidelines
Authors: Santucci Kourtney , Malik Kristina E. , Angione Katie , Bennink Dana , Gerk Andrea , Mancini Drew , Stringfellow Megan , Dinkel Tristen , Demarest Scott , Miele Andrea S. , Saenz Margarita 
Published: October 2024

ABSTRACTRearrangements of the p‐arm of Chromosome 8 can result in a spectrum of neurodevelopmental challenges, along with increased risk of epilepsy, structural brain and cardiac malformations, persisting developmental delays, and other health challenges. The majority of patients reported on in this sample are characterized by an inverted‐duplication deletion rearrangement, but deletions, duplications, and mosaic ring changes in 8p result in similar phenotype. In this report, we add to the phenotypic and functional description of these patients according to their specific chromosomal rearrangement, share neuro‐psychometric values, and propose surveillance care guidelines for caregivers and medical providers of patients with Chromosome 8p Syndromes. Observations from clinical experience with 24 patients seen at our 8p‐dedicated Multi‐Disciplinary Neurogenetics program are shared.
A Strong Candidate Gene for Nonsyndromic Intellectual Disability Phenotype: SGSM3
Authors: Turkyilmaz Ayberk , Saglam Kubra Adanur , Yilmaz Mustafa , Cebi Alper Han 
Published: October 2024

ABSTRACTSGSM proteins are small modulator proteins interacting with proteins in the RAS signaling pathway. Studies with mouse and human tissues indicated that SGSM genes were highly expressed in the brain and could be expressed at different levels at different stages of development in fetal and adult brain tissue. It was first reported by Birnbaum et al. that the SGSM3 gene might be associated with a Mendelian inherited disease in families of Ashkenazi Jews with clinical manifestations of intellectual disability (ID). In this study, a novel homozygous stop‐gain (NM_015705.6: c.1576C>T: p.(Arg526Ter)) variation was detected in the SGSM3 gene in two siblings with short stature and ID findings. The report of two cases with bi‐allelic LOF variants in the SGSM3 gene from different populations with similar clinical manifestations strengthens the potential of this gene as a candidate gene for the nonsyndromic ID phenotype. Functional studies are required to investigate the signaling pathways affected by SGSM3 gene variations to produce the ID phenotype and their effect on the functioning of neurons.
Roost characteristics and fidelity of silver‐haired bat maternity colonies in a floodplain cottonwood forest
Authors: Schwab Nathan A. , Chesonis Tessa N. , Doherty Kyle , Ramsey Philip 
Published: October 2024

AbstractThe maternal roosting behavior of migratory, tree‐dwelling bat species remains poorly understood. From 2016 to 2020 we radio‐tagged 53 adult female silver‐haired bats (Lasionycteris noctivagans) and tracked them to their day roosts to evaluate roosting habits in a cottonwood (Populus) forest in the floodplain of the Bitterroot River in western Montana. We investigated roost tree characteristics of maternity colonies such as canopy closure, tree size, and decay stage, as well as the daily roost fidelity of tagged bats. Additionally, we marked 55 bats with passive integrated transponder (PIT) tags to assess interannual fidelity to summer habitat. We tracked bats to 94 unique roost trees. Based on previous studies, we expected silver‐haired bat maternity colonies to roost in tall, large diameter trees. We modeled roosting probability as a function of tree height, day of year, and the interaction of these terms. We found bats preferred taller trees earlier in the year, but overall roosting probability decreased throughout the season and tree height had lesser influence on roosting probability later in the year. Bats used tall trees with high canopy closure in early stages of decay during periods of pregnancy and lactation, while the effect of these tree attributes lessened later in the season, perhaps after lactation when energetic constraints were reduced for adult females to prepare for migration by entering torpor during the day. Bats used an average of 5.2 roost trees during the young rearing period and remained in the same roost for an average of 1.5 consecutive days. While daily roost fidelity was low, we documented interannual fidelity to summer habitat from nine individuals. We found silver‐haired bat roosting preferences vary with time, are tree‐specific, and policies targeting conservation of the species should manage flood regimes to promote cottonwood establishment, height growth, and a mosaic of riparian habitats.
Wenn der Patient die Wahl hat – Therapiezufriedenheit und Patientenpräferenzen bei der Behandlung aktinischer Keratosen
Authors: Lang Berenice M. , Zielbauer Sebastian , Stege Henner , Grabbe Stephan , Staubach Petra 
Published: October 2024

ZusammenfassungHintergrundAktinische Keratosen (AK) zeigen eine steigende Inzidenz und haben als häufigste (prä)kanzeröse Läsionen der hellhäutigen Bevölkerung einen enormen Behandlungsbedarf. Um die Adhärenz zu erhöhen, ist die Erhebung von therapiebezogenen Bewertungen der verschiedenen Behandlungsarten durch die Patienten von großer Bedeutung.Patienten und MethodikEingeschlossen wurden 100 Patienten mit AK, die mit mindestens zwei verschiedenen Therapieoptionen behandelt wurden. Sie bewerteten ihre Therapien anhand eines Fragebogens (Treatment Satisfaction Questionnaire for Medication [TSQM], maximal 100 Punkte pro Kategorie) und einer Likert‐Skala (LS; 1 = sehr zufrieden, 6 = nicht zufrieden). Ergänzend wurden die Patienten nach ihren Bedürfnissen bezüglich Therapieziel, Kosten, Art, Dauer und Ort der Therapie befragt.Ergebnisse81% der Studienteilnehmer waren männlich. Das Durchschnittsalter war 74 Jahre. 95% wiesen eine Feldkanzerisierung auf. Es wurden acht häufig eingesetzte Therapieverfahren durch die Patienten bewertet (Chirurgie, Kryotherapie, diverse Topika, photodynamische Therapie). Die Zufriedenheitswerte des TSQM lagen zwischen 78,47 ± 16,07 (chirurgische Verfahren) und 53,03 ± 22,13 (Diclofenac in Hyaluronsäure). Statistisch signifikante Unterschiede zwischen den Verfahren ergaben sich nur im Bereich Wirksamkeit. Nebenwirkungen wurden als gering eingestuft. Niedrige Rezidivrate und sichere Entfernung waren die wichtigsten Therapieziele (LS: 1,18 ± 0,44 und 1,27 ± 53).SchlussfolgerungenDas Verständnis der Patientenpräferenzen ist essenziell für die Adhärenz und damit von hoher Bedeutung für den Therapieerfolg von AK. Personalisierte Ansätze sollten bei der Therapiewahl berücksichtigt werden.
Bringing the assessment and treatment of diabetes distress into the real world of clinical care: Time for a shift in perspective
Authors: Fisher Lawrence , Guzman Susan , Polonsky William , Hessler Danielle 
Published: October 2024

AbstractAimsDiabetes distress (DD) refers to the emotional and behavioural challenges associated with managing this demanding chronic disease over time. DD is alarmingly common and it has a significant impact on self‐management behaviours and clinical outcomes. Thus, there is growing recognition that DD is a pressing problem that deserves careful attention in clinical care. Translating the application of validated DD assessment and intervention protocols from the research to the clinical setting, however, presents challenges that require a reconsideration of some common assumptions about what DD is, how prevalent it is, how it presents itself clinically, how it might best be assessed and by whom.MethodsWe employed data from six large‐scale studies using five common DD measures. Using these data, we review and challenge several common assumptions about DD.ResultsThese data suggest that, because of its relative ubiquity, DD should not be viewed as a ‘co‐morbidity’ or ‘complication’ of diabetes and it should not be seen as a mental health/illness ‘condition’. Furthermore, we argue that DD assessment should: (1) be accepted as a standard part of comprehensive diabetes care, (2) occur regularly using broad rather than brief screening measures and (3) be addressed directly by diabetes clinicians, rather than exclusively by behavioural specialists.ConclusionsThe results form the basis of a series of suggestions to enhance the translation, adoption and implementation of DD knowledge derived from the research setting directly into the real world of clinical care.