bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wideband tympanometry in otitis Media
Authors: Elbattat Shymaa M. , Elgharib Amany M. , Gabr Takwa A. 
Published: October 2024

Abstract
Background
Otitis media with effusion (OME) is one of the most frequent infectious diseases in children and is the most common cause of acquired hearing loss in childhood. Diagnosis of OME is mainly dependent on the single-frequency tympanometry. Wideband tympanometry (WBT) is an emerging technology that has been utilized to overcome the limitations of conventional tympanometric procedures. This study aimed to evaluate the diagnostic value of wideband acoustic absorbance in children suffering from otitis media.

Methods
This study included a control group of 50 children with 100 ears with bilateral normal peripheral hearing and bilateral normal middle ear function and a study group which included 100 children with 176 ears complaining of otitis media. Measures included subjects history, basic audiological evaluation and wideband tympanometry. Resonant frequency, tympanometric peak pressure and middle ear absorbance were measured from wideband tympanometry and compared in both groups.

Results
There was a statistically significant reduction of resonsnce frequency in the study group in comparison to the control group. Also, there was a statistically significant reduction of tympanometric peak pressure in the study group in comparison to the control group. As regards the absorbance, there was a statistically significant reduction of absorbance in the study group in comparison to the control group at all tested frequencies (250Hz- 8000Hz). The best area under the receiver operating characteristic curve values for diagnosing OM were obtained at all tested frequencies. Data of this work showed that higher values were mainly at 250Hz, 500Hz and 1kHz (0.84, 0.88 and 0.93 respectively).

Conclusion
Findings of this study suggested that wide band tympanometry can be used efficiently in various degrees of OM.
Pre-emptive augmentative biological control of
Spodoptera frugiperda
in Europe using
Trichogramma
spp.
Authors: Kenis Marc , Zhong Yongzhi , Fontes João , Kenis Julien , Herz Annette , Babendreier Dirk 
Published: October 2024

Abstract

Background

Fall armyworm,
Spodoptera frugiperda
, is a highly invasive pest of maize and other crops worldwide. It has recently been detected in Europe, and it is urgent to test and develop new sustainable control methods adapted to the European context and market.
Trichogramma
spp. are egg parasitoids that are sometimes used as biological control agent against
S. frugiperda
in other continents. However, a major issue using
Trichogramma
spp. against this pest is that females cannot reach all eggs in an egg mass, which is usually composed of one to three layers of eggs, often covered with scales and hair. Three European
Trichogramma
species were tested for their ability to parasitize egg masses with one to three layers and with or without hair and scale cover.

Methods

Trichogramma brassicae
,
T. dendrolimi
and
T. cacoeciae
were offered five types of
S. frugiperda
egg masses: one-layer without hair; one-layer with hair; two-layers without hair; two-layers with hair; three-layers with hair. For each treatment, an egg mass laid on paper was placed in a small vial saturated with females, to be sure that all reachable eggs would be parasitized. For each egg mass, the number of eggs in each layer was counted. Fifteen replicates were made per treatment, as well as 10 control vials without
Trichogramma
sp. Parasitism rates were calculated for each egg mass.

Results

There were significant differences in the ability of parasitoid species to oviposit through hair and scales and to reach the lower egg layers.
Trichogramma dendrolimi
was the most efficient species and
T. cacoeciae
the least. Depending on the number of egg layers and hair and scales, parasitism rates by
T. brassicae
,
T. dendrolimi
and
T. cacoeciae
varied between 99 and 41%, 100 and 43% and 100 and 28%, respectively.

Conclusions

The assays confirmed that
Trichogramma
females cannot easily oviposit through thick layers of hair and scales but overall parasitism rates were higher than found previously. Important variations between species were found, and more
Trichogramma
sp. and other local natural enemies should be tested pre-emptively before
S. frugiperda
has invaded Europe.
Trajectory mapping through channel state information by triangulation method and fine-tuning
Authors: Abuhoureyah Fahd , Wong Yan Chiew , Mohd Isira Ahmad Sadhiqin 
Published: October 2024

AbstractTrajectory mapping techniques have widespread applications in diverse fields, including robotics, localization, smart environments, gaming, and tracking systems. However, existing free devices encounter challenges in representing trajectories, thereby limiting the effectiveness of applications such as robotics, localization, and tracking systems. The imprecise mappings generated by these methods lead to suboptimal performance and unreliable results. The proposed approach leverages WiFi sensing through channel state information (CSI), triangulation techniques, and a fine-tuning mechanism to enhance trajectory precision within indoor environment trajectory mapping. The proposed solution employs a domain adapter fine-tuning technique to enable location-independent tracking via CSI, minimizing errors. The use of CSI MIMO signals for trajectory mapping offers enhanced spatial resolution, robust multipath handling, and improved accuracy in tracking movement by leveraging multiple antenna channels and exploiting the rich information embedded in signal reflections and scattering, while triangulation aids in accurately determining the location of objects or targets. Furthermore, incorporating a fine-tuning mechanism refines the generated trajectories. The findings demonstrate substantial enhancements in mapping precision, with an accuracy of 95.5% in tracking 13 paths within the new domain. These results underscore the effectiveness of the proposed approach in overcoming the limitations of existing methods and achieving highly accurate trajectory mapping.
Digital Voice Analysis as a Biomarker of Acromegaly
Authors: Vouzouneraki Konstantina , Nylén Fredrik , Holmberg Jenny , Olsson Tommy , Berinder Katarina , Höybye Charlotte , Petersson Maria , Bensing Sophie , Åkerman Anna-Karin , Borg Henrik , Ekman Bertil , Robért Jonas , Engström Britt Edén , Ragnarsson Oskar , Burman Pia , Dahlqvist Per 
Published: October 2024

Abstract

Context
There is a considerable diagnostic delay in acromegaly, contributing to increased morbidity. Voice changes due to orofacial and laryngeal changes are common in acromegaly.

Objective
Our aim was to explore the use of digital voice analysis as a biomarker for acromegaly using broad acoustic analysis and machine learning.

Methods
Voice recordings from patients with acromegaly and matched controls were collected using a mobile phone at Swedish university hospitals. Anthropometric and clinical data and the Voice Handicap Index (VHI) were assessed. Digital voice analysis of a sustained and stable vowel [a] resulted in 3274 parameters, which were used for training of machine learning models classifying the speaker as “acromegaly” or “control.” The machine learning models were trained with 76% of the data and the remaining 24% was used to assess their performance. For comparison, voice recordings of 50 pairs of participants were assessed by 12 experienced endocrinologists.

Results
We included 151 Swedish patients with acromegaly (13% biochemically active and 10% newly diagnosed) and 139 matched controls. The machine learning model identified patients with acromegaly more accurately (area under the receiver operating curve [ROC AUC] 0.84) than experienced endocrinologists (ROC AUC 0.69). Self-reported voice problems were more pronounced in patients with acromegaly than matched controls (median VHI 6 vs 2, P &lt; .01) with higher prevalence of clinically significant voice handicap (VHI ≥20: 22.5% vs 3.6%).

Conclusion
Digital voice analysis can identify patients with acromegaly from short voice recordings with high accuracy. Patients with acromegaly experience more voice disorders than matched controls.
Art and Collective Healing
Authors: Tataryan Aslan Nora 
Published: October 2024

Abstract
Sarkis Zabunyan, one of the prominent figures in Turkish contemporary art, was selected to represent the Turkish pavilion in the Venice Biennale in 2015. Since 2015 was the centennial of the Armenian Genocide, a genocide that has not been recognized by the Turkish Republic for more than a hundred years, and Sarkis being an Istanbul Armenian born and raised in Turkey, the selection caused quite a stir and sparked a public discussion on art and collective healing when it was announced. As a result, the catalog of Sarkis’s work Respiro was subjected to censorship. Through this censorship case, this article scrutinizes various reconciliation discourses developed in Turkey in the early 2000s regarding the Armenian Genocide and how contemporary art could possibly engage/disengage with those discourses.
LGBTQIA+ inclusion in the global health policy agenda: A critical discourse analysis of the Lancet Commission report archive
Authors: Rosa William E. , Weiss Goitiandia Sofia , Braybrook Debbie , Metheny Nicholas , Roberts Kailey E. , McDarby Meghan , Behrens Mia , Berkman Cathy , Stein Gary L. , Adedimeji Adebola , Wakefield Donna , Harding Richard , Spence Dingle , Bristowe Katherine 
Published: October 2024

Context
LGBTQIA+ people worldwide experience discrimination, violence, and stigma that lead to poor health outcomes. Policy plays a crucial role in ensuring health equity and safety for LGBTQIA+ communities. Given Lancet Commissions’ substantial impact on health policy across domains, we aimed to determine how LGBTQIA+ communities and their care needs are incorporated throughout Lancet Commission reports and recommendations.

Methods
Using critical discourse analysis, we analyzed 102 Commissions for inclusion of and reference to LGBTQIA+ communities using 36 key terms. Three levels of analysis were conducted: 1) micro-level (overview of terminology use); 2) meso-level (visibility and placement of LGBTQIA+ references); and 3) macro-level (outlining characterizations and framing of references with consideration of broader social discourses).

Findings
36 of 102 (35%) Commissions referenced LGBTQIA+ communities with 801 mentions in total. There were minimal (9/36) references made in the “Executive Summary,” “Recommendations,” and/or “Key Messages” sections of reports. LGBTQIA+ communities were most frequently discussed in reports related to HIV/AIDS and sexual and reproductive health. Few Commissions related to public health, or chronic conditions (9/60) referenced LGBTQIA+ communities. Some reports made non-specific or unexplained references; many discussed the LGBTQIA+ population without specific reference to sub-groups. LGBTQIA+ communities were often listed alongside other marginalized groups without rationale or a description of shared needs or experiences. We identified framings (legal, vulnerability, risk) and characterizations (as victims, as blameworthy, as a problem) of LGBTQIA+ communities that contribute to problematizing discourse.

Conclusions
LGBTQIA+ people were rarely included in the Commissions, resulting in an inadvertent marginalization of their health needs. Policy initiatives must consider LGBTQIA+ groups from a strengths-based rather than problematizing perspective, integrating evidence-based approaches alongside community-based stakeholder engagement to mitigate inequities and promote inclusive care and policymaking.
A Rare Case of Tirzepatide-Induced Hepatotoxicity
Authors: Sohal Aalam , Casanova Luis , Kowdley Kris V. 
Published: October 2024

ABSTRACT
Tirzepatide is the first dual incretin glucose-dependent insulinotropic polypeptide/glucagon-like peptide 1 receptor activator approved for the management of type II diabetes mellitus. This drug was also recently approved by the Food and Drug Administration as a management option for patients with obesity. Tirzepatide has been also reported to be beneficial in reducing liver fat content. Although its efficacy is well described in the literature, no cases of tirzepatide-induced hepatotoxicity have been reported. We report a case of a 37-year-old woman with metabolic syndrome who was noted to have elevated liver enzymes secondary to tirzepatide use.
Aprendizagem matemática: explorando o conceito de função por meio de jogo Pega Varetas
Authors: Santos Caroline dos , Lopes Anemari Roesler Luersen Vieira , Fajardo Ricardo 
Published: October 2024

O presente artigo, que analisa uma situação de ensino desenvolvida no âmbito de uma pesquisa de mestrado, tem como objetivo investigar indicativos da formação do pensamento algébrico por estudantes no estudo do conceito de função, com o uso do jogo Pega Varetas. A abordagem teórica e metodológica adotada baseia-se na perspectiva histórico-cultural. A situação de ensino proposta visava promover a apropriação do conceito de função a partir dos nexos conceituais de variável, campo de variação e dependência. Foi desenvolvida com estudantes do primeiro ano do Curso Técnico em Agropecuária Integrado ao Ensino Médio, de uma escola municipal de Ijuí-RS. As ações foram organizadas na perspectiva de um experimento didático, contemplando como instrumento para apreensão do material empírico registros produzidos em portfólios. Como resultados, evidencia-se a formação do pensamento algébrico em consonância com o desenvolvimento da linguagem algébrica e os sentidos atribuídos pelos estudantes.
Antibacterial compounds derived from marine Streptomyces aureofaciens A3 through in-silico molecular docking
Authors: Srikandace Yoice , Syani Ira Rhabbiyatun , Wahhaab Aisha , Kamarisima Kamarisima , Putri Sastia Prama , Aditiawati Pingkan 
Published: October 2024

Streptomyces aureofaciens widely produces the antibiotic tetracycline and many other compounds during fermentation. The compounds have yet to be known for their antibacterial potential. This work aims to determine new antibiotics or other possible antibacterial compounds produced by marine S.aureofaceiens A3 through an in silico molecular docking method. The ethyl acetate (EA) extracts from fermented marine S. aureofaciens A3 in ISP4 medium enriched with seawater components showed strong antibacterial activity. The antibacterial activity of EA extracts during 6-12 days of fermentation was carried out by the Kirby-Bauer method and the compounds of EA extracts were analyzed by GC/MS. Compounds identified by GC/MS were ligands for an in silico molecular docking study against four target proteins (DNA gyrase, topoisomerase IV, PBP 1a, and DHFR) of pathogenic bacteria. The drug-likeness of selected chemicals as antibacterial agents was assessed using Lipinski's Rule of Five. The results showed the prospective compounds as a narrow-spectrum antibacterial, including 3,5-di-tert-Butyl-4-hydroxyphenylpropionic acid against PBP 1a and Benzenepropanoic acid, and 3,5-bis (1,1-dimethyl ethyl)-4-hydroxy-, methyl esters against DHFR. Substances with broad-spectrum antibacterial activity, such as 3-Acetylphenanthrene and 3-(p-Ethoxyphenyl)-5-(O-tolyloxymethyl)-2-oxazolidone, against multitarget DNA gyrase B and DHFR, 7,9-Di-tert-butyl-1-oxaspiro (4,5) Deca-6,9-diene-2,8-dione against PBP1a and DHFR, and isobenzofuro [5,6-b] benzofuran-8-carboxylic acid, 1,3-dihydro-7,10-dimethoxy-9-methyl-1-oxo-, methyl ester against DNA gyrase B, PBP 1a, and DHFR. On the 12th day of fermentation, two compounds were identified: isobenzofuro[5,6-b] benzofuran-8-carboxylic acid, 1,3-dihydro-7,10-dimethoxy-9-methyl-1-oxo-, methyl ester, and 3-(p-Ethoxyphenyl)-5-(O-tolyl oxy methyl)-2-oxazolidone. This is the first report that these two compounds, known as potential drugs like antibiotics through in silico molecular docking, were first produced by Streptomyces species.
Do instructor beliefs and attitudes matter? Understanding associations between beliefs, attitudes, and practices
Authors: Malhotra Taru , Owston Ron 
Published: October 2024

A mixed-method approach is used to examine the relationship between university instructors’ practices in blended courses and their epistemological and pedagogical beliefs, and their attitudes toward technology. The study draws from a socio-constructive perspective and uses Fishbein and Ajzen’s belief and attitude theory and applies it to a blended framework. Data were collected using an online survey of 71 instructors, semi-structured individual interviews with 24 instructors and one to four classroom observations of 15 instructors. The interviews were audio-recorded, and the classroom observations were collected via hand-written notes. Data were analyzed via NVIVO 12 and SPSS. Findings explore relationships between instructors’ beliefs around knowledge, hard work and student self-regulation skills to their instructional strategies and involvement of students. The study also looks at instructor use of different technologies in blended courses and explores the connection between their attitudes towards technology and their practices. This study, thus, offers guidance to academic leaders, instructors, developers, and policymakers and has several implications for research and instructor development workshops.
Genre effects on alignment and writing quality in the continuation task by Chinese EFL learners
Authors: Zhou Xiao , Wang Qi 
Published: October 2024

Abstract
Previous studies have repeatedly confirmed the robust alignment effect of the continuation task and its great potential to expedite second language writing and learning. The bulk of research in this respect, however, has mainly centred on the narrative genre, leaving the applicability of the task to other genres largely unexplored. This study endeavours to address this issue by comparing the alignment effect and writing performances of the task between the narrative and the expository genre. To this end, a cohort of 40 students from a Chinese university were recruited. They were required to complete two narrative and two expository continuation tasks over eight weeks. Participants’ continuation writings were analyzed both quantitatively and qualitatively for the purpose of capturing alignment effects. The results reveal that the expository continuation task elicited greater overall alignment, manifested in the greater amount of phrasal alignment, albeit smaller amount of sentential alignment. Irrespective of source text genre, students tacitly converged to the source text at various rhetoric and stylistic dimensions, exhibiting alignment in nuanced and multifaceted manner. Participants’ writing performances were found to be better on the expository task, indexed by greater accuracy and syntactic complexity. The findings suggest that the continuation task can be expanded to expository writing to effectively promote the teaching/learning of non-narrative writing. The implications for both L2 writing theory and pedagogy are discussed.
Impact of osteopathic manipulative medicine training during graduate medical education and its integration into clinical practice
Authors: Kramer Joanna L. , Trombetti Kirby , De Asis Kathleen , Mai Vivian , Swing Edward 
Published: October 2024

Abstract

Context
Osteopathic manipulative medicine (OMM) is a unique skill set consisting of physical manipulations that treat the neuromusculoskeletal system. Although OMM can improve patient outcomes such as functionality and pain, as well as increase physician reimbursement, its use is declining. Barriers to its use include a lack of proficiency, support, reimbursement, and time. Knowledge gaps remain as to how OMM training during graduate medical education (GME) affects OMM use.

Objectives
This study describes relationships between OMM exposure during GME and the use of OMM in practice.

Methods
An online survey of physicians in a variety of medical fields during late 2022 assessed the impact of OMM education during postgraduate training on its use in clinical practice. Survey data were analyzed to compare training characteristics and OMM use via chi-square tests and binary logistic regression.

Results
A total of 299 surveys were completed. Respondents who received formal OMM education during residency were more likely (59.8 %) to utilize OMM in medical practice than those who practiced OMM informally (37.8 %, p<0.001) and those who had no OMM exposure during residency (10.3 %, p<0.001). Respondents who trained with more osteopathic attendings (p<0.001) and co-residents (p=0.012) were also more likely to utilize OMM. Those who completed residencies that were accredited by the Accreditation Council for Graduate Medical Education (ACGME) with an Osteopathic recognition track, by the American Osteopathic Association (AOA), and were dually-accredited (ACGME/AOA), were all more likely to utilize OMM (60 %, 56 %, and 53 %, respectively) than those who completed residencies with ACGME accreditation alone (22 %, p<0.01).

Conclusions
Although OMM can improve patient outcomes, it is underutilized by Doctors of Osteopathic Medicine (DOs) in practice. Lack of training after medical school has been identified as a contributing factor to its disuse. The results of our study illustrate that there is a positive association between OMM education during postgraduate training and OMM use in clinical practice.
All-dielectric structural coloration empowered by bound states in the continuum
Authors: Zheng Hong , Hu Haiyang , Weber Thomas , Wang Juan , Nan Lin , Zou Bingsuo , Maier Stefan A. , Tittl Andreas 
Published: October 2024

Abstract
The technological requirements of low-power and high-fidelity color displays have been instrumental in driving research into advanced coloration technologies. At the forefront of these developments is the implementation of dye-free approaches, which overcome previous constraints related to color resolution and fading. Resonant dielectric nanostructures have emerged as a promising paradigm, showing great potential for high efficiency, high color saturation, wide gamut palette, and image reproduction. However, they still face limitations related to color accuracy, purity, and simultaneous brightness tunability. Here, we demonstrate an all-dielectric metasurface empowered by photonic bound states in the continuum (BICs), which supports sharp resonances throughout the visible spectral range, ideally suited for producing a wide range of structural colors. The metasurface design consists of TiO2 ellipses with carefully controlled sizes and geometrical asymmetry, allowing versatile and on-demand variation of the brightness and hue of the output colors, respectively.