bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Turning On’ to Glutathione: A Rhodamine‐Based Fluorescent Chemodosimeter with Nanomolar Sensitivity
Authors: Badekar Pooja S. , Deo Harshada S. , Varma Mokshada E. , Kulkarni Prasad P. , Maibam Ashakiran , Krishnamurty Sailaja , Kumbhar Anupa A. 
Published: September 2024

AbstractA new colorimetric and fluorescence turn‐on chemodosimeter for selective detection of GSH over Cys and Hcy with 34‐fold enhancement in emission intensity is reported. Probe 1 exhibited ultra‐sensitivity toward GSH with 0.125 nM detection limit and successfully displayed GSH detection in MCF‐7 live cells. The mechanism of sensing is established by density functional theoretical calculations.
Antiviral Activity of Pd(II) Complexes with Aminoadamantanes Against Arboviruses
Authors: Silva Laura Barros , Cruz Állefe Barbosa , Pereira Douglas Henrique , Cassani Natasha Marques , Aquino Ruiz Uriel Enrique , Santos Igor Andrade , Martins Daniel Oliveira Silva , Nakahata Douglas Hideki , de Alencar Simoni Déborah , Kanavos Ioannis , Ronga Luisa , Lobinski Ryszard , dos Santos Pereira Anna Karla , Gomes Jardim Ana Carolina , de Paiva Raphael Enoque Ferraz , Corbi Pedro Paulo 
Published: September 2024

AbstractIn this paper, we report the synthesis, structural characterization, and antiviral properties of palladium(II) complexes with amantadine (atd) and memantine (mtn). Elemental and mass spectrometric analyses indicated a 1:2 metal/ligand ratio. The single crystal data for Pd‐mtn revealed that the complex adopts a square geometry with the two memantine ligands bonded to Pd(II) by the nitrogen atoms of the NH2 group, in a trans configuration. Computational studies supported a similar structure for Pd‐atd. The complexes were stable in DMSO solution for 24 h. The antiviral properties of Pd‐atd and Pd‐mtn were evaluated against Zika (ZIKV) and Chikungunya (CHIKV) viruses in vitro at their highest noncytotoxic concentrations. The Pd‐atd (at 2 µM) and Pd‐mtn (at 10 µM) complexes were able to impair 76% and 96% of CHIKV replication, respectively, which points the coordination of amantadine and memantine to Pd(II) as a successful strategy to increase their anti‐CHIKV properties. Conversely, the Pd(II) complexes did not significantly inhibit the replication of ZIKV, which confirms the selectivity towards CHIKV. Interaction of the compounds with N‐acetyl‐l‐cysteine, a model disulfide‐containing peptide, and plasmid DNA pointed to Cys‐containing peptides as more likely targets than nucleotides for the complexes.
Nanoprobe Based on Novel NIR‐II Quinolinium Cyanine for Multimodal Imaging
Authors: Xu Meilin , Lin Yanhong , Li Yuhang , Dong Yao , Guo Chang , Zhou Xiaole , Wang Leyu 
Published: September 2024

AbstractNIR‐II imaging has the advantages of high sensitivity, spatiotemporal resolution, and high penetration depth, thereby serving as a potential alternative to conventional imaging methods. Herein, a novel NIR‐II dye IR‐1010 (λex/λem = 1010/1058 nm) is reported with high quantum yield (3.08%) and good stability, by incorporating p‐methoxyphenyl groups into a quinolinium cyanine dye. Then a multifunctional nanoprobe, termed IUFP NPs, is developed by the incorporation of upconversion (UC) nanoparticles (NPs), perfluoro‐15‐crown‐5‐ether (PFCE), and IR‐1010, to display the novel performance of multimodal imaging. Under the single‐wavelength excitation (980 nm), IUFP NPs simultaneously emit the NIR‐II fluorescence of IR‐1010 and visible UC luminescence of UCNPs, and thus realize the UC imaging for cells, and NIR‐II fluorescence/photoacoustic/19F magnetic resonance imaging for blood vessels, lymph nodes and tumor in mice. This work affords a novel approach to NIR‐II dyes and a general strategy for the design of multimodal imaging probes.
Independent Control Over the H/OH Adsorption: Breaking the Trade‐Off Between H/OH‐Adsorption and H2O‐Dissociation of Platinum‐Group Metal Electrocatalyst for Hydrogen Evolution Reaction
Authors: Zhang Jiachen , Liu Guocong , Li Huiting , Chang Ruixuan , Jia Shuyu , Zhang Yechuan , Huang Kai , Tang Yawen , Sun Hanjun 
Published: September 2024

AbstractPlatinum‐group metals catalysts (such as Rh, Pd, Ir, Pt) have been the most efficient hydrogen evolution reaction (HER) electrocatalysts due to their moderate H adsorption strength, while the high H2O‐dissociation barrier in alkaline media restrains the catalytic performance of PGM catalysts. However, the optimization of the H2O‐dissociation barrier and *H/*OH binding energy toward their individual optima is limited due to the constraints of their scaling relationship on a single active site. Here, a coordinatively unsaturated “M─Ox─W” (M = Rh, Pd, Ir, Pt) active area is constructed, where H and OH species are anchored on Pt‐group metal sites and inactive W sites for individual regulation. By combining experiments and density functional theory calculations, the introduction of extra OH‐adsorption sites (coordinatively unsaturated WO3‐x) avoids the competitive adsorption of H and OH on the single site, while the enhanced OH‐adsorption capacity on the coordinatively unsaturated WO3‐x effectively facilitates the adsorption/dissociation of interfacial H2O. As a result, the representative Rh‐WO3‐x catalyst exhibits outstanding catalytic activity and durability for HER. The findings of this work not only provide valuable insights for the design of efficient PGM catalysts for HER but also shed light on the development of electrocatalysts for other catalytic reactions.
Mathematical modeling and analysis for radiative MHD peristaltic flow of Bingham nanofluid
Authors: Nisar Zahid , Ahmed Bilal , Aziz Arsalan , Muhammad Khursheed , Khalifa Hamiden Abd El‐Wahed , Ahmad Irshad 
Published: September 2024

AbstractThe current study elaborates the mathematical modeling for peristaltic transport of Bingham nanoliquid in symmetric channel with thermal radiation. Here we used non‐Newtonian fluid model (Bingham model) define as Channel boundaries are complaint nature. The equations for the flow and heat/mass transport, incorporating the aspects of thermophoresis and Brownian motion, were derived using Buongiorno's nanofluids framework. Thermal transport involves the existence of Ohmic heating and viscous dissipation consequences. The model's governing equations are derived, made simpler by using long wavelengths and small Reynolds number assumptions. Numerical techniques are utilized for finding the solution of nonlinear systems of equations. Velocity, concentration, temperature, and rate of heat transfer are analyzed graphically. The findings of these investigations could improve fluid dynamics and gastrointestinal movements in a variety of engineering systems. This examination also sheds light on the physiological fluids’ easy movement through the capillaries and arteries, which supports the movement of nutrients, blood circulation, oxygen delivery, waste elimination, temperature regulation, and other essential components within the human organism.
Slip flow of SWCNT–H2O, TiO2–H2O, MWCNT–H2O, and GO–H2O nanofluids between two spinning circular disks
Authors: Singla Tanvi , Sharma Sapna , Kumar Bhuvaneshvar 
Published: September 2024

AbstractThe heat transfer and flow properties of nanofluids are studied using two co‐axial, stretched, and rotating disks containing the porous media and slip boundary conditions. The water‐based nanofluid is formed by using SWCNT (single‐walled carbon nanotubes), (titanium dioxide), MWCNT (multiwalled carbon nanotubes), GO (graphene oxide) as nanoparticles. The nonlinear PDEs are converted into ODEs using the Von Karman similarity transformation. The finite difference method is used to solve the transformed equations. The velocity profiles in the axial, radial, and tangential directions and the temperature profiles are analyzed through graphs, accompanied by interpretations based on physical principles. The energy equation is modeled using the Cattaneo–Christov heat flux model. When the velocity slip parameter rises, axial velocity decreases near the lower disk but increases near the end of the upper disk, while there is a reduction in radial velocity near the end of both disks. The skin friction coefficient and Nusselt number are computed in the present study for governing parameters.
Unsteady chemically reactive heat and mass transfer during Darcy Forchheimer radiative nanofluid flow with slip conditions: Application to nano‐lubrications and cutting process
Authors: Ullah Zia , Alam Md. Mahbub , El‐Zahar Essam R. , Seddek Laila F. , Altohamy Ahmed A. , Kolsi Lioua 
Published: September 2024

AbstractThe novelty of this study is to develop the oscillation, amplitude and periodical behavior of thermal and concentration boundary layers of transient Darcian nanofluid flow over stationary circular cylinder. For the improvement of cutting forces, lubrication and cooling in machining operations, workpiece cutting temperature and tool durability, the nanofluids have significant role with the effects of thermophoretic nanoparticles and rate of reactions. The aim of current work is to deduce the oscillations, amplitude, and frequency analysis of mass and heat transmission of Darcian nanoparticles motion around porous stretchable cylinder with thermal radiation and heat generation effects. For physical and thermo parameters, the governing mathematical equations are transformed into convenient equations. The smooth and similar programing algorithm is developed in FORTRAN language (Lahey‐95) by using primitive and oscillatory stokes transformations. The primitive steady and oscillating model is solved numerically by using Gaussian elimination and implicit finite difference techniques. The steady outcomes of velocity, temperature, and concentration distributions are plotted for various physical parameters within defined boundary values. The range of parameters such as , , , , , and is used. The steady results are again used to display the oscillatory skin friction, oscillating heating rate, and oscillating mass transport around and positions of stretching porous cylinder. The increasing amplitude of velocity and temperature slip distribution grows well as diffusion‐convection parameter and thermal radiation increases at both angles. The slip temperature and slip concentration grows significantly as convective parameter increases. The impact of thermophoresis and rate of reactions enhances the oscillations and amplitudes of mass and heat transmission around stretchable cylinder as porous effect decreases. It is very important in nanofluid lubrications, drilling, rotating, milling, and cutting tools machines.
Froggatt-Nielsen ALP
Authors: Greljo Admir , Smolkovič Aleks , Valenti Alessandro 
Published: September 2024

Abstract
The Froggatt-Nielsen (FN) mechanism, a prominent framework for explaining the observed flavor hierarchies, generically predicts the existence of an axion-like particle (ALP). This work examines a class of FN models based on ℤN discrete symmetries. We chart the allowed parameter space from a set of theoretical considerations and construct explicit renormalizable completions with minimal field content necessary to generate consistent textures. We then conduct comprehensive phenomenological analyses of two particularly elegant ℤ4 and ℤ8 models, highlighting the interplay between the effects of the ALP and the associated UV fields. We find that the FN scale can be as low as a few TeV.
Commutative families in DIM algebra, integrable many-body systems and q, t matrix models
Authors: Mironov A. , Morozov A. , Popolitov A. 
Published: September 2024

Abstract
We extend our consideration of commutative subalgebras (rays) in different representations of the W1+∞ algebra to the elliptic Hall algebra (or, equivalently, to the Ding-Iohara-Miki (DIM) algebra $$ {U}_{q,t}\left({\hat{\hat{\mathfrak{gl}}}}_1\right) $$

U

q
,
t

gl
̂

̂

1

). Its advantage is that it possesses the Miki automorphism, which makes all commutative rays equivalent. Integrable systems associated with these rays become finite-difference and, apart from the trigonometric Ruijsenaars system not too much familiar. We concentrate on the simplest many-body and Fock representations, and derive explicit formulas for all generators of the elliptic Hall algebra en,m. In the one-body representation, they differ just by normalization from $$ {z}^n{q}^{m\hat{D}} $$

z
n

q

m

D
̂

of the W1+∞ Lie algebra, and, in the N -body case, they are non-trivially generalized to monomials of the Cherednik operators with action restricted to symmetric polynomials. In the Fock representation, the resulting operators are expressed through auxiliary polynomials of n variables, which define weights in the residues formulas. We also discuss q, t-deformation of matrix models associated with constructed commutative subalgebras.
Thoracolumbar injuries: non operative treatment: indications, management
Authors: Nau Christoph , Pape Hans Christoph , Jug Marko , Wendt Klaus , Komadina Radko , Bloemers Frank 
Published: September 2024

Abstract
Introduction
Thoracolumbar spine injuries can result from various traumatic events such as falls, motor vehicle accidents, and sports injuries. While surgical intervention is often indicated for complex fractures and in case of neurological deficits, non-operative treatment remains a viable option for certain types of injuries.

Aims
This manuscript aims to provide a comprehensive overview of the specific indications and treatment options of non-operative thoracolumbar spine injuries. It seeks to provide evidence-based recommendations for selecting patients suitable for conservative management based on fracture type and stability, absence of neurological deficits, spine deformity, integrity of the posterior ligament complex and patient specific factors.
The use of multi-task learning in cybersecurity applications: a systematic literature review
Authors: Ibrahim Shimaa , Catal Cagatay , Kacem Thabet 
Published: September 2024

AbstractCybersecurity is crucial in today’s interconnected world, as digital technologies are increasingly used in various sectors. The risk of cyberattacks targeting financial, military, and political systems has increased due to the wide use of technology. Cybersecurity has become vital in information technology, with data protection being a major priority. Despite government and corporate efforts, cybersecurity remains a significant concern. The application of multi-task learning (MTL) in cybersecurity is a promising solution, allowing security systems to simultaneously address various tasks and adapt in real-time to emerging threats. While researchers have applied MTL techniques for different purposes, a systematic overview of the state-of-the-art on the role of MTL in cybersecurity is lacking. Therefore, we carried out a systematic literature review (SLR) on the use of MTL in cybersecurity applications and explored its potential applications and effectiveness in developing security measures. Five critical applications, such as network intrusion detection and malware detection, were identified, and several tasks used in these applications were observed. Most of the studies used supervised learning algorithms, and there were very limited studies that focused on other types of machine learning. This paper outlines various models utilized in the context of multi-task learning within cybersecurity and presents several challenges in this field.
Anticoagulation strategies in patients with coexisting traumatic intracranial hematomas and cerebral venous sinus thrombosis: an observational cohort study
Authors: Antonsson Julia , Tatter Charles , Ågren Anna , Alpkvist Peter , Thelin Eric Peter , Fletcher-Sandersjöö Alexander 
Published: September 2024

Abstract

Purpose
Post-traumatic cerebral venous sinus thrombosis (ptCVT) is a rare but serious complication of traumatic brain injury (TBI). Managing ptCVT is challenging due to the concurrent risk of traumatic intracranial hematoma (ICH) expansion. Limited data exists on the safety and efficacy of anticoagulation therapy (ACT) in these cases.

Methods
This single-center observational cohort study included adult TBI patients with concurrent ICH and ptCVT. Low-molecular-weight heparin (LMWH) or heparin infusion was used to treat all ptCVTs based on institutional protocols. The outcomes of interest were hemorrhagic and thrombotic complications.

Results
Out of 1,039 TBI-patients admitted between 2006 and 2020, 32 met the inclusion criteria. The median time from injury to ptCVT diagnosis was 24 h. ACT was initiated at a median of 9 h after ptCVT diagnosis. Patients were administered either heparin infusion (n = 8) or LMWH at dosages ranging from 28 to 72% of the therapeutic level (n = 24). There were no hemorrhagic complications, even in patients receiving LMWH at ≥ 50% of the therapeutic dose. Thrombotic complications occurred in 3 patients (9.4%) – two cases of thrombus progression and one venous infarct. The patients who developed thrombotic complications differed from those who did not by having a 17-h delay in ACT initiation after diagnosis or by receiving an initial LMWH dose at 28% of the therapeutic level.

Conclusion
LMWH at approximately 50% of the therapeutic level was effective for managing ptCVT associated with TBI in our retrospective dataset, with no risk of hematoma expansion. Prospective trials are warranted to confirm these results.
Is “real” effort more real?
Authors: Dutcher E. Glenn , Salmon Timothy C. , Saral Krista J. 
Published: September 2024

AbstractA growing number of studies use “real” effort designs for laboratory experiments where subjects complete an actual task to exert effort rather than using a stylized effort design where subjects simply choose an effort level from a predefined set. The commonly argued reason for real effort is that it makes the results more generalizable and field relevant. We investigate the nature of modeling effort provision by first trying to provide a clear theoretical understanding of the nature of effort costs. We then empirically examine claims about the differences between real effort and stylized effort. A key to our examination is ensuring that we compare the two modes of effort provision keeping effort costs constant, which is a point overlooked in many past examinations. In our data, when controlling for effort costs, we find no differences in behavior between real and stylized effort. Given the importance of effort costs and the lack of a generally accepted way to include them in real effort designs, we provide a simple add-on that any researcher can use with their real effort experiments to incorporate a theoretically appropriate and controlled cost of effort even in a real effort setting. We also discuss ways to better approach modeling effort costs in experiments, whether one is conducting real or stylized designs, to improve inference on research questions.
Population pharmacokinetics and exposure–response relationships of maribavir in transplant recipients with cytomegalovirus infection
Authors: Song Ivy H. , Chen Grace , Hayes Siobhan , Farrell Colm , Jomphe Claudia , Gosselin Nathalie H. , Sun Kefeng 
Published: September 2024

AbstractMaribavir is approved for management of post-transplant cytomegalovirus (CMV) infections refractory and/or resistant to CMV therapies at a dose of 400 mg twice daily (BID). Population pharmacokinetic (PopPK) and exposure–response analyses were conducted to support the appropriateness of 400 mg BID dosing. A PopPK model was developed using non-linear mixed-effects modeling with pooled maribavir plasma concentration–time data from phase 1 and 2 studies (from 100 mg up to 1200 mg as single or repeated doses) and the phase 3 SOLSTICE study (400 mg BID). Exposure–response analyses were performed for efficacy, safety, and viral resistance based on data collected in the SOLSTICE study. Maribavir PK after oral administration was adequately described by a two-compartment model with first-order elimination, first-order absorption, and an absorption lag-time. There was no evidence that maribavir PK was affected by age, sex, race, diarrhea, vomiting, disease characteristics, or concomitant use of histamine H2 blockers, or proton pump inhibitors. In the SOLSTICE study, higher maribavir exposure was not associated with increased probability of achieving CMV DNA viremia clearance, nor with reduced probability of treatment-emergent maribavir-resistant CMV mutations. A statistically significant association with maribavir exposure was identified for taste disturbance, fatigue, and treatment-emergent serious adverse events, while transplant type, enrollment region, CMV DNA level at baseline, and/or CMV resistance at baseline were identified as additional risk factors for these safety outcomes. In conclusion, the findings of these PopPK and exposure–response analyses provide further support for the recommended maribavir dose of 400 mg BID.
Untangling horsehair fungi in Australia: Marasmius crinis-equi (Marasmiaceae) and related taxa
Authors: Guard F. E. , Dearnaley J. , May T. W. , Lebel T. 
Published: September 2024

Abstract
Fungi with prominent hairlike rhizomorphs, aerial habit, sparse small sporophores, and usually saprotrophic biology are commonly known as ‘horsehair or spider fungi’. The earliest descriptions of them, from the mid-late 1800s, were published from Australian material under the names Marasmius crinis-equi and M. equicrinis. For the original ‘horsehair fungus’, we review this early historical material, briefly explore the changes in the species concept over time, and investigate the nomenclatural tangle of potentially competing names. Our analysis of morphological and molecular data for over 60 collections across eastern Australia shows that material labelled as M. crinis-equi forms part of a complex of at least three closely related species and that this name has been misapplied both within Australia and internationally. An epitype is nominated for an updated concept of M. crinis-equi, and the closely related taxa, M. tropicus sp. nov. and M. kabakada sp. nov., are described. Two more distantly related Australian taxa to which the name M. crinis-equi has been misapplied, M. perumbilicatus sp. nov. and M. argillaceus sp. nov., are also described to further stabilise the concept of the authentic horsehair fungus M. crinis-equi.