bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analytical simulation of Darcy–Forchheimer nanofluid flow over a curved expanding permeable surface
Authors: Rehman Ali , Al-Buriahi M S , Ali H Elhosiny , Jan Rashid , Khan Israr Ali 
Published: October 2024

Abstract
This research paper presents an analytical simulation of Darcy–Forchheimer flow over a porous curve stretching surface. In fluid dynamics, the Darcy–Forchheimer model combines Forchheimer adjustment and high-velocity effects with Darcy’s formula for porous media flow: two nanofluid particles, molybdenum disulphide, and graphene oxide, form nanofluid with the base fluid blood. The governing partial differential equations for momentum and energy are converted into a nonlinear ordinary differential equations system by applying the appropriate similarity transformations. The homotopy analysis method is used to solve the transform equations analytically. The impact of essential factors includes the Forchheimer parameter, porosity parameter, slip parameter, Eckert number, nanoparticle volume friction, magnetic field parameter, and curvature parameter. The results have applications in the design of sophisticated cooling systems, where effective thermal control is essential.
A study on sleep posture analysis using fibre bragg grating arrays based mattress
Authors: Mishra Manish , Sahu Prasant Kumar , Datta Mrinal 
Published: October 2024

Abstract
Prolonged sleeping postures or unusual postures can lead to the development of various ailments such as subacromial impingement syndrome, sleep paralysis in the elderly, nocturnal gastroesophageal reflux, sore development, etc Fibre Bragg Gratings (a variety of optical sensors) have gained huge popularity due to their small size, higher sensitivity and responsivity, and encapsulation flexibilities. However, in the present study, FBG Arrays (two FBGs with 10 mm space between them) are employed as they are advantageous in terms of data collection, mitigating sensor location effects, and multiplexing features. In this work, Liquid silicone encapsulated FBG arrays are placed in the head (E), shoulder (C, D), and lower half body (A, B) region for analyzing the strain patterns generated by different sleeping postures namely, Supine (P1), Left Fetus (P2), Right Fetus (P3), and Over stomach (P4). These strain patterns were analyzed in two ways, combined (averaging the data from each FBG of the array) and Individual (data from each FBG was analyzed separately). Both analyses suggested that the FBGs in the arrays responded swiftly to the strain changes that occurred due to changes in sleeping postures. 3D histograms were utilized to track the strain changes and analyze different sleeping postures. A discussion regarding closely related postures and long hour monitoring has also been included. Arrays in the lower half (A, B) and shoulder (C, D) regions proved to be pivotal in discriminating body postures. The average standard deviation of strain for the different arrays was in the range of 0.1 to 0.19 suggesting the reliable and appreciable strain-handling capabilities of the Liquid silicone encapsulated arrays.
Digital-analog counterdiabatic quantum optimization with trapped ions
Authors: Kumar Shubham , Hegade Narendra N , Henrique de Oliveira Murilo , Solano Enrique , Gomez Cadavid Alejandro , Albarrán-Arriagada F 
Published: October 2024

Abstract
We introduce a hardware-specific, problem-dependent digital-analog quantum algorithm of a counterdiabatic quantum dynamics tailored for optimization problems. Specifically, we focus on trapped-ion architectures, taking advantage from global Mølmer–Sørensen gates as the analog interactions complemented by digital gates, both of which are available in the state-of-the-art technologies. We show an optimal configuration of analog blocks and digital steps leading to a substantial reduction in circuit depth compared to the purely digital approach. This implies that, using the proposed encoding, we can address larger optimization problem instances, requiring more qubits, while preserving the coherence time of current devices. Furthermore, we study the minimum gate fidelity required by the analog blocks to outperform the purely digital simulation, finding that it is below the best fidelity reported in the literature. To validate the performance of the digital-analog encoding, we tackle the maximum independent set problem, showing that it requires fewer resources compared to the digital case. This hybrid co-design approach paves the way towards quantum advantage for efficient solutions of quantum optimization problems.
Local goal-based governance: a novel approach to environmental sustainability in China?
Authors: Xu Jing , Lu Chuntian , Xiang Ning , Liu Meng , Ma Yichen 
Published: October 2024

Abstract
The recent emergence of goal-based governance at global scale may be considered as a new approach to enhance environmental sustainability at local level. This article examines how local goal-based governance actually unfolds with a focus on its fundamental features and effectiveness. We first build a conceptual framework for local goal-based governance which consists of three key elements: nature of problem, setting the goals, and achieving the goals. It provides a set of theoretical propositions: (1) the problems with two defining features are more amendable to goal-setting strategies, (2) setting a specified, practical, and learning-focused goal structure as the key premise, (3) goal attainment is built around a campaign-mode experimentation to try and find out locally appropriate approaches, a double-layered engagement between civil society and statutory institutions, and a system to track the goals through quantitative and qualitative measures. Based on semi-structured interviews and documents analysis, we adopt a case study of Chinese local waste management to test the theory and explain the unique process of local goal-based governance. This article also discusses how local goal-based governance differs from the traditional rule-based governance and further explores how these two governance strategies interact with each other to realize local changes. We highlight two complementary effects: enabling and compensating. Local goal-based governance has unique strengths to compensate for the weakness of rule-based system in promoting civic engagement; and meanwhile rule-based governance creates favorable social conditions within which local goal-based governance is initiated and developed. The inherent challenges and limitations of local goal-based governance are also discussed.
Introduction
Authors: Prontera Andrea 
Published: October 2024

AbstractThis chapter introduces the main themes and goals of this book. It reviews the literature on the global energy transition from fossil fuels to renewables and clarifies this book’s practical and theoretical relevance for the greening of international relations scholarship and the study of foreign energy policy in the emerging low-carbon world. The chapter also presents key data and trends on the development and diffusion of renewable energy, low-carbon technologies, and related supply chains. This data offers a snapshot of the matter at the global level and in key regions and countries, particularly China, the European Union, and the United States, which have emerged as the main players in this field. The chapter explains why these three players can be viewed as green superpowers, although they have adopted varying positions regarding the global energy transition and climate change. Finally, the chapter presents the structure of this book.
Arterial spin labelling could detect the occlusion of inferior petrosal sinus for cavernous sinus dural arteriovenous fistula
Authors: Yoshimura Shota , Morofuji Yoichi , Takahira Ryotaro , Izumo Tsuyoshi , Matsuo Takayuki 
Published: October 2024

Abstract
Several reports indicate that arterial spin labelling (ASL) MRI is useful for the diagnosis, identification of cortical venous reflux, and assessment of therapeutic effect in dural arteriovenous fistula (dAVF). However, there is no reports indicating the utility of ASL in the identification of venous sinus obstruction. We herein report the case of a 72-year-old woman who presented with diplopia and right trigeminal neuralgia due to bilateral cavernous sinus dAVF. Digital subtraction angiography (DSA) showed temporal occlusion of the inferior petrosal sinus (IPS) and ASL indicated hyperintense signal in the IPS. The ASL signal could indicate venous stasis soon after the occlusion based on the serial changes of IPS patency and occlusion observed in the DSA.
Plasma phosphorylated-tau217 is increased in Niemann–Pick disease type C
Authors: Gonzalez-Ortiz Fernando , Karikari Thomas K , Taylor-Te Vruchte Danielle , Shepherd Dawn , Kirsebom Bjørn-Eivind , Fladby Tormod , Platt Frances , Blennow Kaj 
Published: October 2024

Abstract
Niemann–Pick disease type C and Alzheimer’s disease are distinct neurodegenerative disorders that share the presence of neurofibrillary tangle pathology. In this multicentre study, we measured plasma phosphorylated-tau217 in controls (n = 60), Niemann–Pick disease type C (n = 71) and Alzheimer’s disease (n = 30 positive for amyloid and negative for tau in CSF [A+T−] and n = 30 positive for both [A+T+]). Annual Severity Increment Score and Lysotracker measurements were evaluated in the Niemann–Pick disease type C group to estimate the rate of progression and lysosomal enlargement, respectively. In the cross-sectional analysis, plasma phosphorylated-tau217 was increased in Niemann–Pick disease type C compared with controls (2.52 ± 1.93 versus 1.02 ± 0.34 pg/mL, respectively, P &lt; 0.001) and inversely correlated with age at disease onset (R = −0.54, P &lt; 0.001). In the longitudinal analysis, plasma phosphorylated-tau217 was associated with disease progression determined by Annual Severity Increment Score (R = 0.48, P &lt; 0.001) and lysosomal enlargement (R = 0.26, P = 0.004). We found no differences between A+T− Alzheimer’s disease and Niemann–Pick disease type C (2.67 ± 1.18 versus 2.52 ± 1. 93 pg/mL, P = 0.31); however, A+T+ Alzheimer’s disease had significantly higher levels than Niemann–Pick disease type C (3.26 ± 1.36 versus 2.52 ± 1.93 pg/mL, P = 0.001). Our findings suggest that plasma p-tau217 can increase in brain disorders with isolated tau pathology. Plasma p-tau217 associations with disease progression and severity make it a potential marker in Niemann–Pick disease type C.
Findings of the British Association of Dermatologists career survey of dermatologists in training and new consultant dermatologists 2023
Authors: Passby Lauren , Bardhan Ajoy , Griffiths Tamara , Chowdhury Mahbub M 
Published: October 2024

Abstract
Previous surveys of UK dermatology trainees have identified key patterns regarding future career intentions that can help to inform workforce planning as the number of vacancies for dermatology consultants continues to increase. Over a 6-week period between September and October 2023, we invited all doctors currently training in dermatology, as well as all dermatology doctors who completed their training between 2018 and 2023, to complete separate surveys. These surveys explored career locations, working patterns, pull factors toward particular posts and push factors away from dermatology consultant posts in the National Health Service (NHS). The findings of these surveys confirm persisting trends toward less-than-full-time working, trainees’ ongoing limited geographical mobility and a declining appetite for academic work, all identified in previous surveys. This survey offers the first insights into the working lives and factors influencing the career choices of consultants who completed their dermatology training between 2018 and 2023.
Case report: role of multimodality imaging in diagnostics and follow-up of a giant intramyocardial dissecting haematoma
Authors: Dall’Ara Gianni , De Vita Maria , Dallaserra Chiara , Compagnone Miriam , Galvani Marcello 
Published: October 2024

Abstract

Background
Intramyocardial dissecting haematoma (IDH) is a rare life-threatening event usually complicating an acute myocardial infarction. Poor data exist about diagnosis, management, and outcome.

Case summary
We reported a case of giant IDH managed conservatively, thanks to stable clinical status and haemodynamics, which evolved towards resorption. Echocardiography and second-level imaging tools, like computed tomography scan and cardiac magnetic resonance, helped in differential diagnosis and studying the haematoma evolution over time, especially providing data about dimension, connection with the left ventricular cavity, consolidation, and resorption. The course is influenced by many factors including localization, edge integrity, and antithrombotic therapy on board. In this case, IDH resorption was observed despite the huge size and anticoagulant therapy on board, used for secondary cardioembolic protection, under close imaging follow-up.

Discussion
Intramyocardial dissecting haematoma management depends on clinical stability, and imaging provides key data about diagnosis and evolution.
The English Lordship of Ireland and the Irish Sea World: Re-assessing the Origins of the Kildare Ascendancy, c.1390–c.1513
Authors: Egan Simon 
Published: October 2024

Abstract
By 1500, the FitzGeralds of Kildare had established themselves as one of the most powerful entities in Ireland. A considerable body of work has been completed on the rise of this dynasty and their relations with the Tudor monarchy. Scholarship has focused primarily on the career of the eighth earl of Kildare, Gerald FitzGerald (d. 1513): his ability to forge alliances with both the colonial and native Irish nobility has been viewed as a core element in the establishment of his dynasty’s ascendancy. This article seeks to offer a new perspective on the establishment of Kildare power and locates the rise of the Kildare earls within a wider chronological and geographic framework of interpretation. In particular, it argues that the Kildares’ rise to prominence owed much to the earlier efforts of the Butler earls of Ormond. During the early 1400s, the Butlers forged a series of dynastic alliances with the nobility of Ireland’s western seaboard and helped to extend English influence into western Scotland. Following the Butlers’ ejection from Ireland in the 1460s, the FitzGeralds of Kildare appropriated many of these dynastic alliances. This article investigates the Butlers’ relations with the nobility of this ‘wider Irish Sea world’ and explores how events on Ireland’s western seaboard and the Highlands and Islands of Scotland shaped both the emergence and establishment of the Kildare ascendancy, as well as the development of England’s Irish colony during key phases of the Hundred Years War and the Wars of the Roses.
Early outcomes of robotic versus video-thoracoscopic anatomical segmentectomy: a propensity score-matched real-world study
Authors: Gómez-Hernández María Teresa , Forcada Clara , Gómez Francisco , Iscan Mehlika , Fuentes Marta G , Rivas Cristina E , Aranda Jose Luis , Colmenares Oscar , Varela Gonzalo , Jiménez Marcelo F 
Published: October 2024

Abstract

OBJECTIVES
Minimally invasive anatomic segmentectomy for the resection of pulmonary nodules has significantly increased in the last few years. Nevertheless, there is limited evidence on the safety and feasibility of robotic segmentectomy compared to video-assisted thoracic surgery. This study aimed to compare the real-world early outcomes of robotic and video-thoracoscopic surgery in anatomic segmentectomy.

METHODS
Single-centre cohort study including all consecutive patients undergoing segmentectomy by either robotic or video-thoracoscopic from June 2018 to November 2023. Propensity score case matching analysis generated 2 matched groups undergoing robotic or video-thoracoscopic segmentectomy. Short-term outcomes were analysed and compared between groups.

RESULTS
204 patients (75 robotic and 129 video-thoracoscopic patients) were included. After matching, 146 patients (73 cases in each group) were compared. One 30-day death was observed in the robotic group (P = 1). Two conversions to thoracotomy occurred in the robotic, and none in the video-thoracoscopic group (P = 0.5). Surgical time was longer in the robotic group (P = 0.091). There were no significant differences between robotic and video-thoracoscopic groups in postoperative complications (13.7% vs 15.1%, P = 1), cardiopulmonary complications (6.8% vs 6.8%, P = 1), major complications (4.1% vs 4.1%, P = 1), prolonged air leak (4.1% vs 5.5%, P = 1), arrhythmia (1.4% vs 0%, P = 1) and reoperation (2.7% vs 2.7%, P = 1). Median length of stay was 3 days (interquartile range 2–3 days) in the robotic group vs 3 days (interquartile range 2.5–4 days) in the video-thoracoscopic group (P = 0.212).

CONCLUSIONS
Robotic segmentectomy is a safe and feasible alternative to video-thoracoscopy, as no significant differences in early postoperative outcomes were found between the 2 techniques.
How far do oral lectures at European Orthodontic Society congresses reach? A comparison of abstract publication rates, article citations, and social media mentions
Authors: Livas Christos , Pandis Nikolaos , Delli Konstantina 
Published: October 2024

Abstract

Objectives
This study investigated the scientific impact of oral abstracts presented in five consecutive European Orthodontic Society (EOS) congresses in terms of full-text publication rates as well as citations and social media metrics (altmetrics) of the resulting articles.

Methods
PubMed (http://www.ncbi.nlm.nih.gov/pubmed) and Google Scholar (http://scholar.google.nl/) were screened to identify published articles originally presented as lectures at EOS 2015–2019. EOS date, abstract title, subject, number of authors, authors’ names, first author’s country of origin, and type of affiliation were extracted from congress abstract books. Altmetric Attention Scores (AASs), number of X (formerly Twitter) posts, Mendeley reads, and citations of the articles were retrieved from Altmetric Explorer and Web of Science (WoS) databases, respectively. Abstract details, full publication rates and Altmetric mentions and WoS citations of the related articles were analysed using univariable and multivariable logistic regression.

Results
In total, 51.79 to 73.91% of the lectures presented at EOS 2015–2019 were converted into peer-reviewed articles. There was a median interval of 10.95 months (interquartile range 20.5 months) between conference and publication dates. EOS congress year (overall Wald test P-value = .04) and number of authors (overall Wald test P-value &lt; .01) were significant predictors for full-text publication of oral lectures. There was no significant effect of EOS presentation on AASs, citations, X posts, and Mendeley readers (P &gt; .05).

Limitations
Journal impact factors and quartile rankings were not considered to determine the impact of the journals that published articles originally presented as EOS oral abstracts.

Conclusions
Overall, 61.30% of EOS 2015–2019 lectures were published as full-length articles. Multi-authored abstracts presented higher odds of publication, whereas oral abstracts presented at EOS 2015 and 2018 had the lowest probabilities to reach full publication. EOS abstract-based articles were assigned similar numbers of citations and AASs to articles not presented at EOS congresses.
Safety of beta-blocker discontinuation after acute coronary syndromes with preserved or mildly reduced left ventricular ejection fraction: a target trial emulation from a real-world cohort
Authors: Johner Nicolas , Branca Mattia , Carballo David , Baggio Stéphanie , Nanchen David , Tessitore Elena , Räber Lorenz , Lüscher Thomas Felix , Matter Christian M , Windecker Stephan , Rodondi Nicolas , Mach François , Gencer Baris 
Published: October 2024

Abstract

Aims
The benefit of long-term beta-blocker therapy after acute coronary syndromes (ACS) without heart failure in the reperfusion era is uncertain. Two recent randomized trials found conflicting results. The present study assessed the safety of beta-blocker discontinuation within 12 months following ACS with left ventricular ejection fraction (LVEF) ≥40%.

Methods and results
In a multicentre prospective real-world cohort (n = 3762) of patients hospitalized for ACS, patients with LVEF ≥40% and beta-blockers at discharge were included. Patients who continued beta-blockers at 1 year were compared with those who discontinued beta-blockers within 12 months post-ACS using target trial emulation and inverse probability weighting over an additional 4-year follow-up. The primary endpoint was major adverse cardiovascular events (MACE), a composite of 4-year cardiovascular death, myocardial infarction, stroke, transient ischaemic attack, unplanned coronary revascularization, or unstable angina hospitalization. Of 2077 patients, 1758 (85%) continued beta-blockers and 319 (15%) had discontinued beta-blockers at 1 year. The risk of the primary endpoint was similar in both groups [14.1 vs. 14.3% with beta-blocker discontinuation vs. continuation; adjusted hazard ratio (aHR) = 0.98; 95% confidence interval, 0.72–1.34, P = 0.91]. Subgroup analysis suggested a higher risk of primary endpoint with beta-blocker discontinuation after STEMI [aHR = 1.46 (0.99–2.16)] compared with NSTEMI [aHR = 0.70 (0.40–1.22), Pinteraction = 0.033], whereas there was no interaction with LVEF (Pinteraction = 0.68).

Conclusion
Beta-blocker discontinuation within 12 months following ACS with LVEF ≥40% was not associated with an increased risk of MACE compared with long-term beta-blocker therapy. Subgroup analysis suggested potential risk in STEMI patients. Discontinuing beta-blockers 12 months after ACS appears safe in patients with LVEF ≥40%, particularly after NSTEMI.
StereoSiTE: a framework to spatially and quantitatively profile the cellular neighborhood organized iTME
Authors: Liu Xing , Qu Chi , Liu Chuandong , Zhu Na , Huang Huaqiang , Teng Fei , Huang Caili , Luo Bingying , Liu Xuanzhu , Xie Min , Xi Feng , Li Mei , Wu Liang , Li Yuxiang , Chen Ao , Xu Xun , Liao Sha , Zhang Jiajun 
Published: October 2024

AbstractBackgroundSpatial transcriptome (ST) technologies are emerging as powerful tools for studying tumor biology. However, existing tools for analyzing ST data are limited, as they mainly rely on algorithms developed for single-cell RNA sequencing data and do not fully utilize the spatial information. While some algorithms have been developed for ST data, they are often designed for specific tasks, lacking a comprehensive analytical framework for leveraging spatial information.ResultsIn this study, we present StereoSiTE, an analytical framework that combines open-source bioinformatics tools with custom algorithms to accurately infer the functional spatial cell interaction intensity (SCII) within the cellular neighborhood (CN) of interest. We applied StereoSiTE to decode ST datasets from xenograft models and found that the CN efficiently distinguished different cellular contexts, while the SCII analysis provided more precise insights into intercellular interactions by incorporating spatial information. By applying StereoSiTE to multiple samples, we successfully identified a CN region dominated by neutrophils, suggesting their potential role in remodeling the immune tumor microenvironment (iTME) after treatment. Moreover, the SCII analysis within the CN region revealed neutrophil-mediated communication, supported by pathway enrichment, transcription factor regulon activities, and protein–protein interactions.ConclusionsStereoSiTE represents a promising framework for unraveling the mechanisms underlying treatment response within the iTME by leveraging CN-based tissue domain identification and SCII-inferred spatial intercellular interactions. The software is designed to be scalable, modular, and user-friendly, making it accessible to a wide range of researchers.