bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expression of progerin does not result in an increased mutation rate
Authors: Deniaud Emmanuelle , Boyle Shelagh , Bickmore Wendy 
Published: April 2016

AbstractIn the premature ageing disease Hutchinson-Gilford progeria syndrome (HGPS) the underlying genetic defect in thelamin Agene leads to accumulation at the nuclear lamina of progerin – a mutant form of lamin A that cannot be correctly processed. This has been reported to result in defects in the DNA damage response and in DNA repair, leading to the hypothesis that, as in normal ageing and in other progeroid syndromes caused by mutation of genes of the DNA repair and DNA damage response pathways, increased DNA damage may be responsible for the premature ageing phenotypes in HGPS patients. However, this hypothesis is based upon the study of markers of the DNA damage response, rather than measurement of DNA damage per se or the consequences of unrepaired DNA damage -mutation. Here, using a mutation reporter cell line, we directly compared the inherent and induced mutation rates in cells expressing wild-type lamin A or progerin. We find no evidence for an elevated mutation rate in progerin-expressing cells. We conclude that the cellular defect in HGPS cells does not lie in the repair of DNA damage per se.
University social responsibility and brand image of private universities in Bangkok
Authors: Plungpongpan Jirawan , Tiangsoongnern Leela , Speece Mark 
Published: April 2016

Purpose
This research examines the effects of University Social Responsibility (USR) on the brand image of private universities in Thailand. Brand image is important for entry into the consideration set as prospective students evaluate options for university study.USR activities may be implicit or explicit, i.e., actively communicated to external stakeholders. We show that explicit USR can help put a university into the brand consideration set.

Design/methodology/approach
This pilot research uses qualitative interviews to explore perceptions of six private university executives, six M6 (high school) students, and the parents of the M6 students.

Findings
In Thailand, some USR elements are mandated components of quality assurance, but many universities go beyond basic requirements. The university executives talked about USR beyond simply meeting government QA requirements. USR can contribute to competitiveness and it helps produce better, more socially responsible graduates. Communication about USR is done through both online and traditional media, but public knowledge lags somewhat compared to what universities actually do.

M6 students are more aware of university USR activities than their parents because of online media and university roadshows at their schools. USR is not the major factor in choosing a university, and many activities are not well known. However, students and parents think that USR is helpful, and some activities directly impact inclusion in the brand consideration set.

Practical implications
Universities can apply these USR activities to strengthen their brand images and become part of the consideration set. However, they need more careful marketing communications to fully inform stakeholders about the whole range of USR.

Originality/value
The researchers have examined how private Thai universities use USR activities as a part of government mandated QA components. These USR activities can contribute to their brand image and help move the university into the brand consideration set.
Development of the scale for “convergence thinking” in engineering
Authors: Park Sungmi 
Published: April 2016

Purpose
This study defines the concept of ‘convergence thinking’ as a trading zone for knowledge fusion in the engineering field, and develops its measuring scale.

Design/methodology/approach
- Based on results from literature review, this study clarifies a theoretical ground for ‘convergence thinking’. Initial items to measure this concept were verified by content analysis and then finalized. After a pilot test done with 448 college students, gathered data were analysed by item selection and exploratory factor analysis to verify their validity. Next, the main test implemented with 568 college students was analysed with confirmatory factor analysis, for validating the final items to measure ‘convergence thinking’.

Findings
As a result, the scale for ‘convergence thinking’ consists of 52 items to measure the following five factors: synthetic thinking, objective utilization of information, logical thinking, intuitive thinking and subjective thinking. Construct validity and criterion-related validity were performed at last to check this scale’s theoretical construct.

Research limitations/implications
Previous studies have performed limited research methods such as literature reviews and case studies in order to introduce a theoretical paradigm for convergence, convergence education and knowledge fusion. However, this study provides scientific results based on quantitative methodology on convergence motive and convergence thinking.

Practical implications
This study collects data from sophomore through senior students in college for its research purpose. It is because we believe that college education has achieved a certain level of convergence capabilities by teaching a series of convergence related subjects. However, this study did not show difference by grades, so it should be careful to standardize research results without differentiating the grade. Thus, future study should reveal the difference of convergence thinking by grades.

Originality/value
In conclusion, the ‘convergence thinking’ scale developed in this study can be standardized and stable enough to apply to other cases.
Marketing strategies of United Kingdom universities during clearing and adjustment
Authors: Mogaji Emmanuel 
Published: April 2016

Purpose
Clearing system in UK enable students without a University place after exam results have been announced to find suitable vacancies, as it is important for universities to fill their vacancies as any shortfall loses them a lot of money, this research examines marketing strategies adopted by UK Universities on their websites during clearing.

Design/methodology/approach
134 universities websites was content analysed few weeks before clearing and the day before clearing starts. The categories for the analysis included membership of the three main university groups as well as clearing advertisement strategies and advertising theme presented.

Findings
110 universities indicated interest in admitting students through clearing on their websites including 18 of the 24 Russell University Group although more emphasis was laid on adjustment to attract students with better grades. The majority of websites were redesigned to reflect clearing with slides highlighting student satisfaction, guaranteed accommodation and graduate employability.

Research limitations/implications
This exploratory study examines advertising strategies adopted during clearing, it would be interesting to also seek a broader view on advertisement strategies adopted by the Universities throughout the year and extended to a comparative study of higher education marketing across different countries.

Originality/value
As websites have become an integral part of the marketing tools of universities, they should present information relevant to different stakeholders creatively, along with images reflecting their diverse student body and extra-curricular environment. This study will be relevant to university staff dealing with marketing, recruitment and information technology, advertising practitioners and academic researchers.
Factors affecting e-business adoption in SMEs: an empirical research
Authors: Chatzoglou Prodromos , Chatzoudes Dimitrios 
Published: April 2016

Purpose
– Nowadays, small and medium enterprises (SMEs) are incrementally using e-business tools in order to compete in an extremely hostile market and gain global access. The importance of e-business adoption for the economic success and survival of SMEs creates a very interesting field of research. The purpose of this paper is to develop and empirically test a conceptual framework that investigates the factors affecting the e-business adoption decision in SMEs.

Design/methodology/approach
– The examination of the proposed conceptual framework was made with the use of a newly developed structured questionnaire that was distributed to a group of Greek SMEs. The questionnaire was distributed to 600 companies, while 161 usable questionnaires were finally returned. exploratory factor analysis, confirmatory factor analysis, linear regression methods and the structural equation modelling (SEM) technique were used to test the research hypotheses.

Findings
– The proposed model explains 71 per cent of the variance of e-business adoption, with firm size, firm scope, IT infrastructure and internet skills being the most important e-business adoption drivers (with firm size being the most significant). On the other hand, CEOs knowledge, adoption cost, and competitive pressure do not seem to play an important role in the e-business adoption decision.

Research limitations/implications
– A limitation stemming from the implemented methodology is the use of self report scales to measure the constructs of the proposed model. Moreover, the present paper lacks a longitudinal approach, since it is cross-sectional and provides a static picture of e-business adoption.

Practical implications
– The paper makes an effort in order to point out areas that companies should emphasise in order to successfully adopt e-business and, therefore, harvest its potential benefits. Certain practical implications are offered in the final part of the paper.

Originality/value
– First, the present study places SMEs in the centre of its attention, while the contemporary research mostly examines the implementation of e-business practices in large organisations. Second, the present study proposes a three-dimensional conceptual framework, including technological, organisational and environmental context. Such a multidimensional approach has randomly been explored in the existing literature. Third, the results of the study may be generalised in other developed countries with similar economic realities and yield interesting outcomes for practitioners in these countries.
Attitude segmentation of Indian online buyers
Authors: Mathew Priya Mary 
Published: April 2016

Purpose
– The purpose of this research paper is to apply the ABC model and examine the attitudinal segmentation of online consumer in India in terms of internet usage, perceived risks, website attributes, intent to do online purchase in future and preference of website attributes.

Design/methodology/approach
– A structured questionnaire was administered to 600 online consumers using field and online survey mediums. The logit analysis was applied to arrive at segmentation of online users.

Findings
– Findings show how attitudes are different of online users when they were segmented based on internet usage. This segmentation showed attitudes that were paradoxical in nature. To explain this paradoxical behaviour of online buyers, this study applied the logit analysis. The online users were further examined applying the ABC model of attitude. Three distinct segments of online users emerged. They are: CAB, CBA and BCA.

Practical implications
– The findings of this paper will be useful for online retailers who want to start e-commerce business in India. The findings are also useful for designing appropriate promotion and marketing strategies to entice online users to become online buyers.

Originality/value
– The key contributions of this paper are the new insights from using the ABC model. Based on usage of internet in number of hours, online buyers could be segmented into four groups. On further analysis using ABC model, this studied showed that a better segmentation of online buyers is possible and that is called attitudinal segmentation. The BCA attitudinal segment is a finding of this study and is unique to this research. This has not been done using Indian online buyers and this adds to the originality of the study.
Strategies in managing risks in the adoption of business analytics practices
Authors: Gangotra Amrita , Shankar Ravi 
Published: April 2016

Purpose– There are various risks that can derail the adoption of business analytics (BA) practice in a telecom service provider (TSP) thereby jeopardising the possibility to increase profitability and improved customer experience. The purpose of this paper is to analyse different associated risks using situation-actor-process, learnings-actions-performance (SAP-LAP) model and build mitigation strategies for the adoption. Also the risks are ranked using the interactive ranking process (IRP) methodology and the dominating matrix provides insight to the actions and actors that need attention to improve the processes and performance.Design/methodology/approach– A case study of a TSP (X1) was analysed through close interactions with experts within the company and externals involved in setting up the BA practice in X1. Using the SAP-LAP framework risks were identified and then the IRP was used to rank the actors w.r.t performance and actions w.r.t processes.Findings– X1 has taken initiatives for setting up the BA practice in order to improve the profitability and customer experience through data insights. The suggested conceptual SAP-LAP model helps to address risk mitigation strategies for its adoption and the IRP frameworks helps in understanding the prioritisation matrix (using the ranking) to be considered to mitigate the risks.Research limitations/implications– The IRP framework is limited to certain relationships between actors, w.r.t processes and actions w.r.t performance for the prioritisation matrix of identified risks. This has scope to be further expanded to other relationships and therefore refining the findings. Also this approach could be used to study other industries too.Practical implications– SAP-LAP model identifies the risks in adopting the BA practice in a TSP. The synthesis of SAP leads to LAP, which bridges the gap by suggesting improvement actions based on the learning from the present situation, actors and processes. IRP provides the prioritisation matrix for mitigating the risks by identifying the dominating factors.Originality/value– BA practice plays a dominant role in a TSP. An approach to study the risks of its adoption using the SAP-LAP and IRP framework bridges the gap between the academic and corporate world. This paper is very relevant to managers involved in setting up a BA practice. For the academic, use of research model validates the identification of risks that are recognised in the corporate world and prioritising the risks that need to be addressed.
Perceived benefits and costs of intellectual capital in small family firms
Authors: Grimaldi Michele , Cricelli Livio , Greco Marco 
Published: April 2016

Purpose– Despite the flourishing literature on intellectual capital (IC), few studies explored its features in the perspective of family firms, and even fewer focussed on small family firms (SFFs). The purpose of this paper is to analyze how managers and senior employees in SFFs perceive the benefits and costs of intellectual capital assets (ICAs) and provides many insights for future researches.Design/methodology/approach– Taking the lead from the constructivist epistemology, this instrumental study describes the implementation of a framework for the assessment of ICAs into four SFFs in order to develop general theoretical principles.Findings– Among the findings, it stands out that most SFFs in the sample especially rely on their internal processes and on their human resources’ knowledge and competences. Furthermore, the authors found much internal disagreement with respect to the expected costs of investing on ICAs, especially within firms operating in more turbulent markets.Research limitations/implications– Being referred to a multiple case study, the results may not be generalized to other organizations. Nevertheless, they are useful to build theory, either by verification of falsification, and to encourage their future testing in empirical papers.Practical implications– The implementation of the framework allows identifying internal disagreement with respect to the ICAs’ costs and benefits and exploring their causes. Furthermore, it suggests which should be the ICAs deserving primary attention in order to have the best impact on value creation.Originality/value– The paper investigates IC in SFFs, thus contributing to fill a remarkable gap in IC literature.
Intellectual capital and performance measurement in healthcare organizations
Authors: Pirozzi Maria Grazia , Ferulano Giuseppe Paolo 
Published: April 2016

Purpose– The purpose of this paper is to define a new conceptual framework or model, to measure and manage organizational performance, both financial/non-financial and intellectual capital (IC), in a healthcare organization.Design/methodology/approach– The integrated new model is produced by integrating the common assessment framework (CAF) model with two other frameworks representing the IC and leadership. These already existing models are originated, respectively by the Health Agency of Emilia-Romagna Region (Italy) and the National Healthcare System (NHS – UK). The integration phase is operated by comparing the CAF and IC models so as to assess the determinant factors that are present in both frameworks and eliminating such redundancies. Concerning the leadership determinant factor, the relevant conceptual framework of CAF model is substituted by the new leadership model proposed by the NHS.Findings– A new integrated model is made available for a subsequent step of empirical implementation and validation through its application in a healthcare organization. The main advantage of this model is the ability to measure and manage IC and financial/non-financial performance. Moreover, the use of a single measurement system facilitates the interpretation and coherency assessment of measured data so originated.Originality/value– The added value this work provides will enrich the academic literature regarding performance measurement systems in healthcare organizations, also providing an original integrated model that is able to exhibit the advantages highlighted above.
Intellectual capital and financial performance in the Serbian ICT industry
Authors: Dženopoljac Vladimir , Janoševic Stevo , Bontis Nick 
Published: April 2016

Purpose– The purpose of this paper is to examine whether intellectual capital (IC) creates value in the Serbian information communication technology (ICT) sector. More specifically, it examines the degree to which IC and its key components affect the financial performance of selected ICT companies compared to effects on physical and financial capital.Design/methodology/approach– The analysis included 13,989 Serbian ICT companies during 2009-2013. Value-added intellectual coefficient (VAIC) was used to measure the level of IC contribution to value creation. Measures of financial performance used in the study were return on equity, return on assets, return on invested capital, profitability, and asset turnover.Findings– Results indicate that, when using firm size and leverage as control variables, only capital-employed efficiency has significant effect on financial performance. Finally, the research confirms that there were no significant differences in financial performance among different ICT subsectors.Research limitations/implications– Main research limitation is related to the disadvantages of VAIC as the measure of IC’s contribution to value creation.Practical implications– Owners and managers of Serbian ICT companies must recognize the importance of managing both the physical capital and the intangible resources embedded in their employees and processes.Originality/value– This is the first paper to examine comprehensively the impact of IC on financial performance in the ICT sector in a transitional economy. This study differs from prior studies in that the authors analyzed every company that operated in Serbian ICT sector.
Attachment and mentoring
Authors: Banerjee-Batist Rimjhim , Reio Thomas G. 
Published: April 2016

Purpose– The purpose of this paper is to examine the relationships between attachment styles, mentoring (psychosocial support and career support), organizational commitment, and turnover intent of protégés in formal faculty mentoring.Design/methodology/approach– An internet survey was conducted with a population of 125 protégés in a formal faculty mentoring program at a US university.Findings– Results from linear regression analyses revealed that protégés’ secure attachment was positively and significantly related with their organizational commitment and was negatively and significantly related to intent to turnover. Additional linear regression analyses revealed that psychosocial support and career support were positively and significantly related with protégé organizational commitment and were negatively and significantly related to intent to turnover. Hierarchical regression showed that secure attachment alone was a unique predictor of protégés’ organizational commitment and intent to turnover. Further, attachment and career support interacted to predict both organizational commitment and intent to turnover.Research limitations/implications– Although psychosocial support and career support in mentoring influence organizational commitment and turnover intent, protégés who are securely attached experience more support. Furthermore, career support the positive association between secure attachment and organizational commitment and the negative association between secure attachment and turnover intent.Originality/value– Little research has specifically addressed attachment and its links to mentoring and organizational outcomes such as organizational commitment and turnover intent in the context of faculty mentoring. Therefore, the study contributes to the understanding of how attachment and mentoring influence organizational commitment and turnover intent in academe.
The Relationship of Practice, Attitude, and Perception of Competence in Middle School Physical Education
Authors: Scrabis-Fletcher Kristin , Rasmussen Jennifer , Silverman Stephen 
Published: April 2016

PurposeGrounded in social cognitive theory this study examined attitude and perception of competence and their relationship with skill practice in middle school physical education.Method:Participants (N = 81) were randomly selected from nine teachers’ classes. Two lessons were videotaped and students completed a middle school perception of competence survey (Scrabis-Fletcher & Silverman, 2010), and a physical education attitude survey (Subramaniam & Silverman, 2000). Student practice trials and task time were coded during skill instruction. A series of different analyses were conducted including descriptive, correlational, and multiple regressions to allow for in-depth understanding of the relationship of student practice and the psychosocial variables of perception of competence and attitude, along with the type and amount of practice occurring in class.Results:Analyses revealed interesting findings about how class time was spent along with a significant correlation for the total number of tasks and appropriate trials per minute and a low correlation between the psychosocial factors and practice variables.Discussion:Including more tasks may increase the number of appropriate practice trials. The sociocognitive bidirectional relationship however, is not predictive in nature and needs to be examined more discreetly from the student, contextual, and teacher perspectives.