bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pass It On! by M. Sadler
Authors: Tan Maria 
Published: May 2016

Sadler, Marilyn. Pass It On! Maplewood, NJ: Blue Apple Books, 2012. Print.Marilyn Sadler enjoys writing funny children’s stories and has authored over 30 books. Through her role as executive producer and writer for the Disney Channel, Sadler has seen some of her works turned into children’s movies and TV series. In Pass It On! Sadler puts a new spin on the traditional game of Telephone, with comical results.‘Cow is stuck in the fence! Pass it on!’ Cow’s friend, Bee starts the ball rolling, sending out a plea to the other animals, recruiting their help to rescue Cow. The original message quickly gets distorted and becomes increasingly absurd, leaving the reader wondering: will anyone come to Cow’s aid?With its simple plot and humorous characters, this story is fun, engaging, and perfect for shared reading with young children. Michael Slack, recognized for his humorous character art, shines in this illustrated work. He is skillful in his use of colour and texture, creating expressive depictions of the animals in the story while conveying a sense of urgency and excitement. The typeset used for the comic-book-like speech bubbles differentiates the characters’ speech from narrative aspects of the story and cues the reader to the tone and dynamic of the animals’ pronouncements.I recently read this to a group of four and five-year-olds, after playing the Telephone game with them. Throughout the story, the children responded with exclamations of, “That’s not right!” and a chorus of, “Pass it on!” as each animal communicated his or her misinterpretation of the message.Highly recommended: 4 out of 4 stars Reviewer: Maria TanMaria is a Public Services Librarian at the University of Alberta’s H. T. Coutts Education Library. She enjoys travelling and visiting unique and far-flung libraries. An avid foodie, Maria’s motto is, “There’s really no good reason to stop the flow of snacks”.
Physiological and histological approaches to study berry shrivel in grapes
Authors: Zufferey Vivian , Spring Jean-Laurent , Voinesco Francine , Viret Olivier , Gindro Katia 
Published: May 2016

<p class="StyleTitre2TimesNewRomanToutenmajuscule" style="text-align: justify;"><strong>Aims</strong>: The current work aims to study berry shrivel in grapes (a grape-ripening disorder) in relation to vine water status and climatic conditions using physiological and histological approaches.</p><p style="text-align: justify;"><strong>Methods and results</strong>: Measurements of rachis hydraulic conductance on grapevine clusters (<em>Vitis vinifera</em> L.) and observations of the vascular tissues (xylem and phloem) using transmission electron microscopy were conducted on rachises from healthy clusters and clusters having berry shrivel (BS) symptoms during the season. BS intensity was largely dependent on the vine water status: BS was greater in vines without water stress than in vines with moderate to high water stress around veraison time. Preliminary results showed that rachis hydraulic conductance declined sharply after veraison but remained slightly higher in healthy clusters in comparison with clusters presenting BS symptoms. An important degradation of the primary phloem was observed in the rachises of BS clusters, with the appearance of hard, non-functional liber (secondary phloem) and a disorganization of the cell content in the phloem tissue. An alteration of the primary xylem was also observed in the middle of the rachis and in the secondary rachis ramifications.</p><p style="text-align: justify;"><strong>Conclusion</strong>: These results suggest that the decrease in sugar and water accumulation in BS berries would primarily be associated with a decline in rachis phloem functionality.</p><p style="text-align: justify;"><strong>Significance and impact of the study</strong>: The management of the vine water status plays a key role in berry shrivel development.</p>
Visual Soil Structure Effects of Tillage and Corn Stover Harvest in Iowa
Authors: Tormena Cassio A. , Karlen Douglas L. , Logsdon Sally , Cherubin Maurício R. 
Published: May 2016

Core Ideas
VESS detected soil structural quality changes under corn stover harvest and tillage systems.
A high level of corn stover harvest had an adverse effect on the soil structural quality.
Under high stover harvest, structural quality in chisel plow was worse than in no‐tillage.
VESS should be further evaluated as an integrative soil quality/health indicator.
High levels of corn (Zea mays L.) stover harvest for ethanol production have raised concerns regarding negative consequences on soil structure and physical quality. Visual soil structure assessment methods have the potential to help address these concerns through simple, straightforward on‐farm evaluations. Our objective was to determine if the visual evaluation of soil structure (VESS) approach could detect soil structural quality differences associated with different levels of corn stover harvest and tillage practices. We evaluated no harvest and moderate and high stover harvest levels within no‐tillage (NT) and chisel plow (CP) plots following 7 yr of continuous corn. Undisturbed 10‐ by 20‐ by 25‐cm soil samples were taken using a spade in April 2015. The thickness and structural quality (Sq) scores for the 0‐ to 5‐ (top) and 5‐ to 20‐cm (bottom) soil layers were determined, and an overall Sq was computed. The Sq values showed a significant interaction between corn stover harvest and tillage practice. Soil structural quality showed no significant differences between NT and CP systems for either the no‐ or moderate‐harvest treatments, but with a high stover harvest rate, CP structural quality was worse than NT. With NT, both moderate and high rates of stover harvest significantly increased Sq compared to no harvest; in CP, there was no significant difference between the no‐ and moderate‐harvest treatments. Only a high level of stover harvest had an adverse effect on the Sq rating. The VESS approach was sensitive for detecting the effects of corn stover harvest and tillage systems on soil structural quality and should be further evaluated as an integrative, on‐farm soil quality/health indicator.
Synthetic bone graft versus autograft or allograft for spinal fusion: a systematic review
Authors: Buser Zorica , Brodke Darrel S. , Youssef Jim A. , Meisel Hans-Joerg , Myhre Sue Lynn , Hashimoto Robin , Park Jong-Beom , Tim Yoon S. , Wang Jeffrey C. 
Published: May 2016

The purpose of this review was to compare the efficacy and safety of synthetic bone graft substitutes versus autograft or allograft for the treatment of lumbar and cervical spinal degenerative diseases. Multiple major medical reference databases were searched for studies that evaluated spinal fusion using synthetic bone graft substitutes (either alone or with an autograft or allograft) compared with autograft and allograft. Randomized controlled trials (RCT) and cohort studies with more than 10 patients were included. Radiographic fusion, patient-reported outcomes, and functional outcomes were the primary outcomes of interest.
The search yielded 214 citations with 27 studies that met the inclusion criteria. For the patients with lumbar spinal degenerative disease, data from 19 comparative studies were included: 3 RCTs, 12 prospective, and 4 retrospective studies. Hydroxyapatite (HA), HA+collagen, β-tricalcium phosphate (β-TCP), calcium sulfate, or polymethylmethacrylate (PMMA) were used. Overall, there were no differences between the treatment groups in terms of fusion, functional outcomes, or complications, except in 1 study that found higher rates of HA graft absorption.
For the patients with cervical degenerative conditions, data from 8 comparative studies were included: 4 RCTs and 4 cohort studies (1 prospective and 3 retrospective studies). Synthetic grafts included HA, β-TCP/HA, PMMA, and biocompatible osteoconductive polymer (BOP). The PMMA and BOP grafts led to lower fusion rates, and PMMA, HA, and BOP had greater risks of graft fragmentation, settling, and instrumentation problems compared with iliac crest bone graft.
The overall quality of evidence evaluating the potential use and superiority of the synthetic biological materials for lumbar and cervical fusion in this systematic review was low or insufficient, largely due to the high potential for bias and small sample sizes. Thus, definitive conclusions or recommendations regarding the use of these synthetic materials should be made cautiously and within the context of the limitations of the evidence.
Reappearance of arteriovenous malformations after complete resection of ruptured arteriovenous malformations: true recurrence or false-negative early postoperative imaging result?
Authors: Aboukaïs Rabih , Vinchon Matthieu , Quidet Mathilde , Bourgeois Philippe , Leclerc Xavier , Lejeune Jean-Paul 
Published: May 2016

OBJECTIVE
Ruptured arteriovenous malformations (AVMs) are often obliterated after emergency microsurgical treatment. However, some studies have reported AVM recurrence after the obliteration of ruptured AVMs. The authors report their experience with AVM recurrence after successful microsurgical treatment of ruptured AVMs.

METHODS
The authors reviewed the medical data of 139 consecutive patients who underwent microsurgery at the authors' institution for ruptured AVM between 2002 and 2012. Each patient underwent a conventional cerebral angiography examination immediately after the surgery. Subsequent follow-ups were performed with MR angiography after 6 months, and, if there was no indication of AVM recurrence, patients were followed up with conventional cerebral angiography between 1 and 2 years after the treatment; pediatric patients were followed up until age 18 years. Recurrence was defined as new radiological evidence of an AVM at the site of a ruptured AVM or a new hemorrhage in patients with angiographically documented AVM obliteration on postoperative angiograms.

RESULTS
The mean age of the patients at the time of ruptured AVM diagnosis was 30.8 years (SD ± 5, range 4–69 years), and 44 of the patients were younger than 18 years (the mean age at diagnosis in this pediatric subgroup was 11.4 years [range 4–17.9 years]). Complete AVM obliteration after the initial microsurgery was observed in 123 patients (89.5%). Reappearance of an AVM was noted in 7 patients between 12 and 42 months after the treatment, and all of these patients were younger than 18 years. The recurrent AVM was located in an eloquent zone in 4 patients, and deep venous drainage was noted in 3 patients. Radiosurgery was performed in 6 of these patients, and 1 patient underwent another microsurgical procedure. The authors noted only one rebleeding due to an AVM recurrence during the latency period after radiosurgery.

CONCLUSIONS
The recurrence of an AVM is fairly rare and affects mostly pediatric patients. Therefore, especially in children, long-term angiographic follow-up is required to detect AVM recurrence or an AVM remnant. The authors stress the need for discussion involving a multidisciplinary neurosurgical team to decide on treatment in cases of any AVM recurrence or remnant.
Outcomes of chronic subdural hematoma with preexisting comorbidities causing disturbed consciousness
Authors: Abe Yasuaki , Maruyama Keisuke , Yokoya Shigeomi , Noguchi Akio , Sato Eishi , Nagane Motoo , Shiokawa Yoshiaki 
Published: May 2016

OBJECTIVE
Chronic subdural hematoma (CSDH) is widely treated by drainage through a bur hole opening. However, whether and how preexisting comorbidities causing disturbance of consciousness affect patient outcomes remains unclear.

METHODS
The authors analyzed 188 consecutive patients with CSDH who were surgically treated at the Neurosurgery Institute of the Kyorin University School of Medicine between 2010 and 2012 and followed them for more than 90 days. The mean patient age was 77.0 years (range 33–101 years) and 56 were women. Patient outcomes including modified Rankin Scale (mRS) score, postoperative morbidity and mortality, and recurrence 90 days after initial surgery were analyzed according to preexisting comorbidities causing disturbance of consciousness. The comorbidities observed in 46 patients (24%) included dementia (30 patients), history of ischemic stroke (10 patients), psychiatric disorders (3 patients), and others (3 patients).

RESULTS
Background characteristics of patients with comorbidities showed older patient age (p < 0.001), lower preoperative Glasgow Coma Scale score (p < 0.001), and higher preoperative mRS score (p < 0.001). The mean mRS score 90 days after the neurosurgical procedure was 1.2 in all 188 patients, which was significantly higher in those with comorbidities (p < 0.001). By 1-way ANOVA with repeated measures, interaction existed between the presence of comorbidities and mRS score, and improvement of mRS score was observed in smaller proportions of patients with comorbidities (p = 0.002). By multivariate logistic regression analysis, the presence of comorbidities, patient age, reoperation for recurrence, and preoperative mRS score were significantly related to poor outcomes, defined as mRS score of 3 or more at 90 days after surgery. Postoperative morbidity (p < 0.01) and mortality (p < 0.01) were significantly higher in those with comorbidities, whereas the rate of recurrence of CSDH was not significantly different.

CONCLUSIONS
The preexistence of comorbidities causing disturbance of consciousness affected severity and outcomes 90 days after surgical treatment of CSDH, and comorbidities were also correlated with aging.
Surgical outcomes after laminoplasty for cervical spondylotic myelopathy in patients with renal dysfunction and/or aortic arch calcification
Authors: Sakaura Hironobu , Miwa Toshitada , Kuroda Yusuke , Ohwada Tetsuo 
Published: May 2016

OBJECTIVE
The authors recently reported that the presence of chronic kidney disease (CKD) and/or extended abdominal aortic calcification was associated with significantly worse clinical outcomes after posterior lumbar interbody fusion. CKD is one of the highest risk factors for systemic atherosclerosis. Therefore, impaired blood flow due to atherosclerosis could exacerbate degeneration of the cervical spine and neural tissue. However, there has been no report of a study evaluating the deleterious effects of CKD and atherosclerosis on the outcomes after decompression surgery for cervical compression myelopathy. The purpose of this study was thus to examine whether CKD and systemic atherosclerosis affect surgical outcomes after laminoplasty for cervical spondylotic myelopathy (CSM).

METHODS
The authors analyzed data from 127 consecutive cases involving patients who underwent laminoplasty for CSM and met their inclusion criteria. Stage 3–4 CKD was present as a preoperative comorbidity in 44 cases. Clinical status was assessed using the Japanese Orthopaedic Association (JOA) cervical myelopathy evaluation questionnaire before surgery and 2 years postoperatively. As a marker of systemic atherosclerosis, the presence of aortic arch calcification (AoAC) was assessed on preoperative chest radiographs.

RESULTS
AoAC was found on preoperative chest radiographs in 40 of 127 patients. Neither CKD nor AoAC had a statistically significant deleterious effect on preoperative JOA score. However, CKD and AoAC were significantly associated with reductions in both the JOA score recovery rate (mean 36.1% in patients with CKD vs 44.7% in those without CKD; 26.0% in patients with AoAC vs 48.9% in those without AoAC) and the change in JOA score at 2 years after surgery (mean 2.3 points in patients with CKD vs 3.1 points in those without CKD; 2.1 points for patients with AoAC vs 3.2 points for those without AoAC). A multivariate regression analysis showed that AoAC was a significant independent predictor of poor outcome with respect to both for the difference between follow-up and preoperative JOA scores and the JOA score recovery rate.

CONCLUSIONS
CKD and AoAC were associated with increased rates of poor neurological outcomes after laminoplasty for CSM, and AoAC was a significant independent predictive factor for poor outcome.
Variation in Recent Onset Parkinson’s Disease: Implications for Prodromal Detection
Authors: Swallow Diane M.A. , Lawton Michael A. , Grosset Katherine A. , Malek Naveed , Smith Callum R. , Bajaj Nin P. , Barker Roger A. , Ben-Shlomo Yoav , Burn David J. , Foltynie Thomas , Hardy John , Morris Huw R. , Williams Nigel , Wood Nicholas W. , Grosset Donald G. ,   on behalf of PRoBaND Clinical Consortium
Published: May 2016

Background: The detection of prodromal Parkinson’s disease (PD) is desirable to test drugs with neuroprotective potential, but will be affected by known disease variations. Objective: To assess the prevalence of four key non-motor prodromal PD markers, and evaluate the sensitivity of case detection when non-motor screening tools for prodromal PD are implemented in an early clinical PD cohort. Methods: Hyposmia (University of Pennsylvania smell identification test ≤15th centile or Sniffin’ Sticks at or ≤10th centile corrected for age and sex), rapid-eye movement sleep behaviour disorder (RBD questionnaire >4), constipation (<1 daily spontaneous bowel motion) and depression (Leeds >6) were recorded in recent onset PD cases, and proposed non-motor screening criteria applied. Results: In 1,719 PD cases, mean age 68.6 years (SD 8.1), 65.5% male, mean disease duration 1.3 years (SD 0.9), 72.2% were hyposmic, 43.3% had RBD, 22.1% depression, and 21.5% constipation. 11.6% of cases had no key non-motor features, 38.8% one, 32.1% two, 15.5% three, and 2.0% all four. Increasing numbers of non-motor features were associated with younger age ( p = 0.019), higher motor scores ( p < 0.001), more postural instability gait difficulty (PIGD) ( p < 0.001), greater cognitive impairment ( p < 0.001) and higher total non-motor burden ( p < 0.001). Cases with hyposmia alone were younger ( p < 0.001), had less severe cognitive ( p = 0.006) and other non-motor features ( p < 0.001). All screening criteria selected younger patients ( p = 0.001, p < 0.001), three of four greater overall non-motor burden ( p = 0.005, p < 0.001), and inclusion of RBD more cognitive impairment ( p = 0.003, p = 0.001) and PIGD ( p = 0.004, p = 0.001). Conclusions: Varying sensitivity levels, and age and phenotype selectivity, are found when different non-motor screening methods to detect prodromal PD are applied to an early clinical PD cohort.
Slowness in Movement Initiation is Associated with Proactive Inhibitory Network Dysfunction in Parkinson’s Disease
Authors: Criaud Marion , Poisson Alice , Thobois Stéphane , Metereau Elise , Redouté Jérôme , Ibarrola Danièle , Baraduc Pierre , Broussolle Emmanuel , Strafella Antonio P. , Ballanger Bénédicte , Boulinguez Philippe 
Published: May 2016

Background: Impairment in initiating movements in PD might be related to executive dysfunction associated with abnormal proactive inhibitory control, a pivotal mechanism consisting in gating movement initiation in uncertain contexts. Objective: Testing this hypothesis on the basis of direct neural-based evidence. Methods: Twelve PD patients on antiparkinsonian medication and fifteen matched healthy controls performed a simple reaction time task during event-related functional MRI scanning. Results: For all subjects, the level of activation of SMA was found to predict RT on a trial-by-trial basis. The increase in movement initiation latency observed in PD patients with regard to controls was associated with pre-stimulus BOLD increases within several nodes of the proactive inhibitory network (caudate nucleus, precuneus, thalamus). Conclusions: These results provide physiological data consistent with impaired control of proactive inhibition over motor initiation in PD. Patients would be locked into a mode of control maintaining anticipated inhibition over willed movements even when the situation does not require action restraint. The functional and neurochemical bases of brain activity associated with executive settings need to be addressed thoroughly in future studies to better understand disabling symptoms that have few therapeutic options like akinesia.
Cortical Implications of Advancing Age and Disease Duration in Parkinson’s Disease Patients with Postural Instability and Gait Dysfunction
Authors: Herb Joshua N. , Rane Swati , Isaacs David A. , Van Wouwe Nelleke , Roman Olivia C. , Landman Bennett A. , Dawant Benoit M. , Hedera Peter , Zald David H. , Neimat Joseph S. , Wylie Scott A. , Donahue Manus J. , Claassen Daniel O. 
Published: May 2016

Background: Parkinson’s Disease patients with predominant gait dysfunction appear to have reduced cortical thickness compared to other motor phenotypes. The extent to which advancing age or disease duration impact the pattern of these distinctions is unclear. Objective: We examine if PD patients with predominant signs of postural instability and gait dysfunction are distinguished by distinct patterns of cerebral atrophy, and how these differences are influenced by age and disease duration. Methods: The Unified Parkinson’s Disease Rating Score (UPDRS) was administered to 196 PD patients (age = 61.4±8.9yrs) in the Off and On dopamine state. All completed a structural T1-weighted brain MRI. We defined 3 motor phenotypes: tremor dominant, akinetic-rigid, and postural instability with gait disorder. General linear modeling quantified cortical thickness in relation to disease duration, and motor improvement after dopaminergic therapy. Cortical thickness and subcortical volumes were compared between the three motor subtypes, after controlling for disease duration and age. Results: We identified 177/196 patients who met criteria for a motor subtype. When corrected for disease duration, postural-instability patients had marked cortical thinning of the bilateral frontal-temporal and posterior cortical regions (cuneus/precuneus). After regressing for age, reduced frontal thickness was evident in patients with gait dysfunction. Widespread cortical thinning was associated with increasing disease duration and reduced motor improvement to dopaminergic therapy. Conclusions: Results emphasize that the profile of motor signs, especially prominent gait manifestations, relate to cortical thinning in distinct regions. Unique patterns of atrophy appear to be driven by advancing pathology related to age and disease duration.
Neuropsychological Profiles in Mild Cognitive Impairment due to Alzheimer’s and Parkinson’s Diseases
Authors: Hessen Erik , Stav Ane Løvli , Auning Eirik , Selnes Per , Blomsø Linn , Holmeide Cathrine Emilie , Johansen Krisztina Kunszt , Eliassen Carl Fredrik , Reinvang Ivar , Fladby Tormod , Aarsland Dag 
Published: May 2016

Background: Neuropsychological comparisons between patients with mild cognitive impairment due to Parkinson’s disease (MCI-PD) and Alzheimer’s disease (MCI-AD) is mostly based on indirect comparison of patients with these disorders and normal controls (NC). Objective: The focus of this study was to make a direct comparison between patients with these diseases. Methods: The study compared 13 patients with MCI-PD and 19 patients with MCI-AD with similar age, education and gender. The participants were recruited and assessed at the same university clinic with equal methods. Results: The main finding was that on group level, MCI-AD scored significantly poorer on learning and memory tests than MCI-PD, whereas MCI-PD were impaired on 1 of 3 measures of executive functioning. Conclusion: MCI-AD performed poorer learning and memory tests, whereas MCI-PD only scored below the employed cut-off on one single executive test. In general, MCI-PD was noticeably less cognitively impaired than MCI-AD.