bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypertension-Associated Expenditures Among Privately Insured US Adults in 2021
Authors: Kumar Ashutosh , He Siran , Pollack Lisa M. , Lee Jun Soo , Imoisili Omoye , Wang Yu , Kompaniyets Lyudmyla , Luo Feijun , Jackson Sandra L. 
Published: September 2024

BACKGROUND:
There are no recent estimates for hypertension-associated medical expenditures. This study aims to estimate hypertension-associated incremental medical expenditures among privately insured US adults.

METHODS:
We conducted a retrospective cohort study using IQVIA’s Ambulatory Electronic Medical Records-US data set linked with PharMetrics Plus claims data. Among privately insured adults aged 18 to 64 years, hypertension was identified as having ≥1 diagnosis code or ≥2 blood pressure measurements of ≥140/90 mm Hg, or ≥1 antihypertensive medication in 2021. Annual total expenditures (in 2021 $US) were estimated using a generalized linear model with gamma distribution and log-link function adjusting for demographic characteristics and cooccurring conditions. Out-of-pocket expenditures were estimated using a 2-part model that included logistic and generalized linear model regression. Overlap propensity score weights from logistic regression were used to obtain a balanced sample on hypertension status.

RESULTS:
Among the 393 018 adults, 156 556 (40%) were identified with hypertension. Compared with individuals without hypertension, those with hypertension had $2926 (95% CI, $2681–$3170) higher total expenditures and $328 (95% CI, $300–$355) higher out-of-pocket expenditures. Adults with hypertension had higher total inpatient ($3272 [95% CI, $1458–$5086]) and outpatient ($2189 [95% CI, $2009–$2369]) expenditures when compared with those without hypertension. Hypertension-associated incremental total expenditures were higher for women ($3242 [95% CI, $2915–$3569]) than for men ($2521 [95% CI, $2139–$2904]).

CONCLUSIONS:
Among privately insured US adults, hypertension was associated with higher medical expenditures, including higher inpatient and out-of-pocket expenditures. These findings may help assess the economic value of interventions effective in preventing hypertension.
The Major Additions in the Samaritan Pentateuch Tradition
Authors: Dayfani Hila 
Published: September 2024

Abstract
One of the most prominent characteristics of the SP tradition is the inclusion of major additions in the text, which consist of material duplicated from other parts of the Pentateuch. While most of these additions involve mechanical and faithful copying of the Pentateuchal material, this paper discusses four major additions that reflect distinctive editorial practices. The editors responsible for these additions slightly revise the copied material, primarily through moderate-sized omissions, in a manner that responds to the tension and congestion inherent within it. Recognizing the peculiarity of this group of variants has implications for the literary development of the SP.
Karl Korsch on Marx’s New Materialism
Authors: Roso Darren 
Published: September 2024

Abstract
This article systematically reconstructs the key elements of the articulation of Marx’s new materialism by Karl Korsch, Weimar Germany’s anti-Stalinist and anti-Social Democratic Marxist heretic. After a brief biographical presentation, and a sketch of the topography of philosophical positions prior and contemporary to him, I develop a thematic presentation of Korsch’s reading of Marx’s materialist dialectics, this-sidedness, the coincidence of consciousness and reality, the problem of application, his salvaging of the category of content, the materialist conception of history and his efforts to produce a theory of the material reproduction of ideology.
Development of Career Guidance and Counseling Needs Scale: a Study from Pakistan
Authors: Keshf Zehra , Nadeem Arif , Khawar Rabia 
Published: September 2024

Abstract
Career Guidance and Counseling Needs Scale (CGCNS) was developed to assess career related needs of students. Initially 143 items were generated from verbatim of university students who participated in qualitative exploratory interviews conducted earlier. Item pool was shortened to 90 items and 67 items respectively after two successive revisions. Content validity was established by expert review from 10 experts resulting in a 57-items scale. For standardization, CGCNS was administered to 480 (451 after data cleaning) public sector university students selected through stratified random sampling. Demographic Sheet, Perceived Stress Scale, and Career Decision-Making Indicators Scale were used for establishing validity. Through EFA, four factors were generated titled Career Foresight, Career Difficulties, Career Dissonance, and Career-Related Self-Awareness. Final CGCNS had 41 items. Alpha reliability and split-half reliability was 0.88 and 0.80 (p < .001) respectively. Convergent validity was 0.76 and concurrent validity was 0.70 (p < .001). Pakistan and other similar countries could benefit from CGCNS.
Proteomic and transcriptomic analysis of cold- and heat-tolerant black soldier fly (Hermetia illucens) larvae
Authors: Feng X. , Memon F.U. , Ma C. , Zhu J. , Huang Z. , Tettamanti G. , Li K. , Peng G. , Hu W. , Tian L. 
Published: September 2024

Abstract
The larvae of black soldier fly (BSFL) can convert organic waste into insect proteins. Their bioconversion performance is considerably reduced under hot and cold conditions. To address this problem, we performed selective breeding of BSFL at 16 °C (T16) and 40 °C (T40), and evaluated differentially expressed genes and proteins in the heat- and cold-tolerant breeds. Both the T16 and T40 breeds exhibited higher body weight, survival rate, and substrate reduction efficiency compared to the control groups (C16 and C40). Transcriptome analysis showed significant gene expression changes in both the T16 and T40 groups at various time points compared to the control groups. Specifically, the T16 group had 84 upregulated and 64 downregulated genes, while the T40 group had 117 upregulated and 483 downregulated genes. Full-length transcriptome analyses revealed 27,414 new transcripts in the T16 group. Proteomic analysis revealed 57 upregulated and 114 downregulated proteins in the T16 group, and 128 upregulated and 68 downregulated in the T40 group. The upregulated genes, proteins, and novel transcripts in the bred strains mainly participated in Toll and Imd signalling, carbon metabolism, carbohydrate metabolism, fatty acid biosynthesis and metabolism, and amino acid metabolism. These findings provide insights into the molecular mechanisms that help BSFL adapt to cold and heat stress.
Novel Approaches to Interim Protection Against Systemic Threats to the Rule of Law
Authors: Fisicaro Marco 
Published: September 2024

Abstract
The article explores the evolution of a key, yet relatively obscure, instrument relating to the ‘head’ of proceedings before the European Court of Human Rights (Court), namely interim measures. By employing the decisions related to the Polish rule of law crisis as a case study, the article contends that the Court’s use of interim measures in this context exhibits significant novelties compared to its previous practice, regarding both the scope and content of interim protection. More broadly, the Polish case study, along with other recent developments in the Court’s practice under Rule 39 of the Rules of Court, highlights a growing tendency to use interim measures for addressing systemic issues in the Contracting Parties. This aspect prompts a reflection on the evolving nature and function of interim relief under the European Convention on Human Rights, and on the outstanding procedural shortcomings of the Rule 39 machinery, which is currently undergoing a process of reform.
Exploring the Myth of National Language in Inoue Hisashi’s Kiiroi Nezumi
Authors: Hausler Rebecca 
Published: September 2024

Abstract
The article discusses the interconnected history of colonialism and the imposition of monolingual and national languages on linguistic minorities in both Australia and Japan, as explored in the Japanese novel Kiiroi Nezumi by Inoue Hisashi. This 1977 novel, set primarily during World War ii, compares the experiences of Australia’s First Nations peoples and Japan’s Tōhoku peoples under the rule of a dominant monolingual and monocultural government. This article analyses Inoue’s novel with reference to how language shapes and communicates identity and culture. Furthermore, the novel explores how the myth of a national language in both Japan and Australia was deliberately manipulated to reinforce the idea of a homogeneous society. Inoue’s fiction explores, critiques and parodies nationalism, with a focus on Japan and Australia’s shared history of domestic imperialism, and the problematic nature of historic amnesia that both countries continue to practise around historical and current issues of race and minority groups.
“Trying to Wring an Ocean from the Precious Few Drops”: Language, Identity and Intergenerational Migrant Trauma in Second-Generation Fiction
Authors: Maher Brigid 
Published: September 2024

Abstract
This article analyses three recent works by second-generation Australian writers—Peter Polites’ Down the Hume (2017), Tracey Lien’s All That’s Left Unsaid (2022) and Omar Sakr’s Son of Sin (2022)—examining the ways in which these authors represent and engage with the reality of multicultural and multilingual Australia. Each of the novels speaks from the perspective of a young Australian for whom English is the native language, while the parents’ home language can be a marker of identity or provoke feelings of clumsiness, inadequacy or alienation. Polites and Sakr intersperse their writing with words and phrases in Greek, Arabic and Turkish in a realistic depiction of code-switching and complex cultural identities. Meanwhile, Lien unpacks some of the complexities of child language brokering and the struggle for language maintenance in her exploration of the intense familial and linguistic pressures that stem from intergenerational trauma in the Vietnamese community.
Steric Sea Level Rise and Relationships with Model Drift and Water Mass Representation in GFDL CM4 and ESM4
Authors: Krasting John P. , Griffies Stephen M. , Tesdal Jan-Erik , MacGilchrist Graeme , Beadling Rebecca L. , Little Christopher M. 
Published: September 2024

Abstract
Density-driven steric seawater changes are a leading-order contributor to global mean sea level rise. However, intermodel differences in the magnitude and spatial patterns of steric sea level rise exist at regional scales and often emerge during the spinup and preindustrial control integrations of climate models. Steric sea level results from an eddy-permitting climate model, GFDL CM4, are compared with a lower-resolution counterpart, GFDL-ESM4. The results from both models are examined through basin-scale heat budgets and watermass analysis, and we compare the patterns of ocean heat uptake, redistribution, and sea level differ in ocean-only [i.e., Ocean Model Intercomparison Project (OMIP)] and coupled climate configurations. After correcting for model drift, both GFDL CM4 and GFDL-ESM4 simulate nearly equivalent ocean heat content change and global sea level rise during the historical period. However, the GFDL CM4 model exhibits as much as a 40% increase in surface ocean heat uptake in the Southern Ocean and subsequent increases in horizontal export to other ocean basins after bias correction. The results suggest regional differences in the processes governing Southern Ocean heat export, such as the formation of Antarctic Intermediate Water (AAIW), Subpolar Mode Water (SPMW), and gyre transport between the two models, and that sea level changes in these models cannot be fully bias-corrected. Since the process-level differences between the two models are evident in the preindustrial control simulations of both models, these results suggest that the control simulations are important for identifying and correcting sea level–related model biases.
Biomarkers in the diagnosis, prognosis and management of rheumatoid arthritis: A comprehensive review
Authors: Sahin Didem , Di Matteo Andrea , Emery Paul 
Published: September 2024

Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune condition that primarily affects the joints and periarticular soft tissues. In the past two decades, the discovery of new biomarkers has contributed to advances in the understanding of the pathogenesis and natural history of RA. These biomarkers, including genetic, clinical, serological and imaging biomarkers, play a key role in the different stages and aspects of RA, from the so called ‘pre-clinical RA’, which is characterized by subclinical pathological events, such as autoimmunity and inflammation, to diagnosis (including differential diagnosis), treatment decision making and disease monitoring. This review will provide an overview on the current role of traditional and newer biomarkers in the main aspects of RA management, from the identification of individuals ‘at-risk’ of RA who are likely to progress to clinically evident disease, to ‘early’ diagnosis of RA, prognosis, precision medicine, and prediction of response to treatment.
Exploring the use of electroconvulsive therapy in the anticoagulated population: A systematic review
Authors: Khalid Ashna , Khalid Aafreen , Waite Sue , Plevin David 
Published: September 2024

Background: Electroconvulsive therapy is an effective treatment for several psychiatric conditions. There are theoretical risks associated with electroconvulsive therapy in patients who are anticoagulated. However, there is no review investigating these adverse effects. Aim: This systematic review explored the literature on using electroconvulsive therapy in anticoagulated patients, including adverse effects associated with continuation or cessation of anticoagulation during electroconvulsive therapy. Methods: The study was registered on PROSPERO (registration CRD42023432178). A search was conducted across CENTRAL, Embase, Medline and PsychINFO databases, with title and abstract screening, full-text review and data extraction by two independent reviewers. Patients planned for electroconvulsive therapy and on anticoagulation prior to electroconvulsive therapy were included. Papers not related to electroconvulsive therapy or anticoagulation were excluded. Data were recorded in Microsoft Excel, presented in tables. Results: The studies comprised 108 patients and over 700 sessions of electroconvulsive therapy. 64.81% patients were on warfarin, 22.22% on a direct-acting oral anticoagulant, 5.55% on heparin and the rest on enoxaparin, dalteparin, acenocoumarol or bemiparin. There were two reports of both nonfatal non-central nervous system bleeding and pulmonary embolism in patients with anticoagulation. There were no intracranial haemorrhages or deaths. Bridging or substitution with an anticoagulant with a shorter half-life had no additional benefit. Conclusion: This review showed tolerability of anticoagulants continued throughout electroconvulsive therapy, with most patients reporting no adverse effects. Given limitations including few studies and medical comorbidities influencing patient risk profile, further studies are required to guide practice recommendations and review long-term outcomes.
Childhood Trauma and Parental Burnout: The Mediating Role of Difficulties in Emotion Regulation and Reflective Functioning
Authors: Ensanimehr Narges , Dehshiri Gholam Reza , Mousavi Seyyedeh Fatemeh 
Published: September 2024

This study investigated the mediating role of difficulties in emotion regulation and reflective functioning in the association between childhood trauma and parental burnout. The participants included 402 mothers with children ranging in age from 1 to 6 years. Mothers completed the Parental Burnout Assessment (PBA) the parental reflective functioning questionnaire (PRFQ), the Difficulties in Emotion Regulation Scale (DERS), and the Childhood Trauma Questionnaire (CTQ). Data analysis was performed using SPSS 26, and Hayes Macro in SPSS was also used to analyze the effects of mediating variables. The results show that although childhood trauma and parental burnout do not have a direct and significant relationship, there is a significant indirect relationship through difficulties in emotional regulation and the two factors of parental reflective functioning, i.e., pre-mentalization, interest and curiosity about mental states. These findings contribute to the understanding of the importance of variables such as difficulties in emotion regulation and reflective functioning, which play a mediating role in the relationship between childhood trauma and parental burnout. This suggests that designing interventions and prevention to reduce parental burnout based on emotion regulation and reflective functioning may be beneficial.
Energy performance certificate calculation methodologies across Europe and accommodating new performance indicators
Authors: Sayfikar Mahsa , Jenkins David P. 
Published: September 2024

Energy Performance Certificates (EPC) are used across Europe to communicate the energy performance of buildings to a range of different end users. However, as new approaches are introduced and guided at the European level via the Energy Performance Buildings Directive (EPBD), the ability of assessment methodologies and assessors to accommodate these new forms is likely to differ due to the significantly different frameworks in each country. The Horizon-funded crossCert project investigates this by identifying how EPC methodologies differ across countries, highlighting the implications of these differences on the performance gap and what that means for future innovations. Results indicate that methodologies vary considerably regarding general approaches, from highly standardised to highly tailored and assessor qualifications. This paper will look at such differences and investigate how these differences can affect future efforts towards improving EPCs. Practical application: With the recent recast of the Energy Performance of Buildings Directive (EPBD) emphasising the need for future innovations of EPCs across Europe and encouraging next-generation EPCs, it is important to study country-specific calculation methodologies. In particular, the lack of harmonisation in different approaches can make top-down innovations difficult to implement and raise questions about how an individual country can or should respond to those guidelines. This paper explores the variations in different aspects of EPC assessment methodologies across 10 European countries and how these differences impact the EPC performance gap and future metrics.
Theory Use in Project Management Research: An Exploratory Content Analysis Approach
Authors: Karanja Erastus , Zaveri Jigish , Miles Angela K. , Day Steven 
Published: September 2024

The frequency and richness of the theories developed, tested, and used by researchers in an academic discipline exemplify several pertinent factors, namely, the growth, the maturity, the independence, the legitimacy, and the influence of the discipline. Although organizations have been working on projects for centuries, Project Management (PM) is a considerably new academic discipline with emerging research themes, models, methodologies, frameworks, and paradigms. These PM concepts are anchored on or reinforced by new or existing theories. This exploratory study aims to add to the existing PM body of knowledge by investigating the prevalence of theory use in PM research. A systematic content analysis of 9200 PM research articles published from 2000 to 2019 (20 years) in the leading PM journals identified 248 unique theories. These results reveal that the PM discipline is increasingly embracing the use of theories with game theory, fuzzy theory, agency theory, contingency theory, and stakeholder theory emerging as the most dominant theories in the reviewed research articles. Also, although PM is developing its theories, the results revealed that PM researchers continue to heavily use theories borrowed from other academic disciplines such as psychology, sociology, mathematics, and economics.
Mediating Role of Social Support and Family Functioning on Quality of Life of Family Caregivers of Individuals With Alcohol Use Disorder
Authors: Kalra Hunny , Tung Suninder 
Published: September 2024

Background:Caring for persons with alcohol use disorder (AUD) significantly affects the quality of life (QoL) of caregivers. According to Lazarus and Folkman’s Stress and Coping Model (1984), the severity of alcohol consumption (SAC) is a major stressor for AUD caregivers. These stressors impact well-being, with QoL linked to caregivers’ coping resources, especially social support (SS) and family functioning (FF). The study aimed to investigate the mediating roles of SS and FF in the relationship between the SAC and caregivers’ QoL.Material and Methods:A cross-sectional study was conducted in two psychiatric hospitals in Amritsar city, Punjab. We used a purposive sampling technique to collect data from 128 family caregivers aged 18 and above who were caring for male patients with AUD aged between 20 and 65. The assessment tools used were the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF), Alcohol Use Disorders Identification Test (AUDIT), Family Assessment Device (FAD), and PGI Social Support Questionnaire (PGI SSQ).Results:There is a significant and partial mediation of the association between SAC and QoL by both SS and FF ( P < .001, 99% CI). Moreover, SAC (r = –0.519), FF (r = –0.603), and SS (r = 0.641) showed significant correlations with caregivers’ QoL ( P < .001). The mean scores for SAC, SS, FF, and QoL were 22.66 (11.38), 50.88 (9.45), 127.18 (43.85), and 84.13 (18.70), respectively, suggesting moderate SAC in patients, moderate to high perceived SS levels, moderate perception of family dysfunction, and moderate to high QoL among the caregivers.Conclusion:SAC detrimentally impacts caregivers’ QoL both directly and indirectly through SS and FF, with the latter serving as mediators, partially mitigating SAC’s negative impact. Clinical implications underscore the importance of tailored interventions, emphasizing the strengthening of support systems and consideration of diverse FF domains for personalized approaches. The findings contribute valuable insights for developing targeted interventions customized to the specific needs of AUD caregivers to enhance their overall QoL.