bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional awareness and expression therapy, cognitive behavioral therapy, and education for fibromyalgia: a cluster-randomized controlled trial
Authors: Lumley Mark A. , Schubiner Howard , Lockhart Nancy A. , Kidwell Kelley M. , Harte Steven E. , Clauw Daniel J. , Williams David A. 
Published: August 2017

Abstract
Patients with fibromyalgia (FM) experience increased lifetime levels of psychosocial adversity, trauma, and emotional conflict. To address these risk factors, we developed emotion awareness and expression therapy (EAET) and tested its benefits against an active control condition, FM education, and the field's gold standard intervention for FM, cognitive behavioral therapy (CBT) for symptom management. Adults with FM (N = 230) formed 40 treatment groups, which were randomized to EAET, CBT, or education and given 8, 90-minute sessions. Patient-reported outcomes were assessed at baseline, posttreatment, and 6-month follow-up (primary end point). Retention of patients to follow-up was excellent (90.4%). Intent-to-treat analyses indicated that although EAET did not differ from FM education on pain severity (primary outcome), EAET had significantly better outcomes than FM education on overall symptoms, widespread pain, physical functioning, cognitive dysfunction, anxiety, depression, positive affect, and life satisfaction (between-condition d's ranging from 0.29-0.45 SD) and the percentage of patients reporting being “very much/much” improved (34.8% vs 15.4%). Emotional awareness and expression therapy did not differ from CBT on the primary or most secondary outcomes, but compared to CBT, EAET led to significantly lower FM symptoms (d = 0.35) and widespread pain (d = 0.37) and a higher percentage of patients achieving 50% pain reduction (22.5% vs 8.3%). In summary, an intervention targeting emotional awareness and expression related to psychosocial adversity and conflict was well received, more effective than a basic educational intervention, and had some advantages over CBT on pain. We conclude that EAET should be considered as an additional treatment option for FM.
Comparison of Epidermal Growth Factor Receptor Gene Mutations Identified Using Pleural Effusion and Primary Tumor Tissue Samples in Non–Small Cell Lung Cancer
Authors: Liu Nan , Sun Rui-Ze , Du Jiang , Dong Qian-Ze , Fan Chui-Feng , Li Qing-Chang , Wang En-Hua , Liu Yang 
Published: August 2017

Background:
Although the use of pleural effusion samples for epidermal growth factor receptor (EGFR) testing in lung cancer is increasing, the accuracy rate and effectiveness of identifying EGFR mutations using these samples, rather than primary tumor tissue samples, is not established.

Materials and Methods:
One hundred ninety-two advanced, non–small cell lung cancer patients were enrolled into this study. All patients had primary tumor tissue and corresponding pleural effusion samples, and we employed the Amplification Refractory Mutation System to detect EGFR gene mutations in these samples.

Result:
The number of EGFR mutations detected in primary tumor tissue and pleural effusion samples was 119 (61.98%) and 113 (58.85%), respectively. The EGFR-mutation rate was significantly higher in female than in male patients, and in adenocarcinoma than in nonadenocarcinoma patients (P=0.000). Single mutations in exons 19 and 21 were the predominant observed mutation type, and the overall concordance rate of EGFR-mutation status between the 192 matched pleural effusion and primary tumor tissue samples was 86.98%.

Conclusions:
We observed a high concordance rate between EGFR mutations identified using primary tumor tissue and corresponding pleural effusion samples by Amplification Refractory Mutation System. Thus, it is likely that pleural effusion sampling from advanced non–small cell lung cancer patients, especially those with adenocarcinoma, may be effective in EGFR-mutation screening.
Aortic Dissection and Severe Renal Failure 6 Years After Kidney Transplantation
Authors: Dujardin Amaury , Le Fur Awena , Cantarovich Diego 
Published: August 2017

Abstract
We report the case of a patient with long-term history of hypertension, presenting with transient neurological disorders and severe graft failure several years after kidney transplantation. Cause of end-stage renal disease was hypertensive nephrosclerosis. Chronic hemodialysis lasted for 1 year. After transplantation and throughout follow-up, serum creatinine ranged from 200 to 230 μmol/L and maintenance immunosuppression included sirolimus and low-dose steroids. Six years after transplantation, the patient presented with right hip pain radiating to the lower back, transient aphasia, confusion, and hemiparesis. Surprisingly, progressive anuria was established requiring dialysis. After numerous nonconclusive investigations including renal histology, a contrast computed tomography scan discovered a Stanford B aortic dissection from the left common carotid artery and left subclavian artery to bilateral internal and external iliac arteries, including the right femoral artery. No surgical treatment was opted and hemodialysis, tight control of blood pressure and oral anticoagulation were established. Immunosuppression was lightened to low-dose steroids alone. After 8 months, chronic dialysis was stopped, and today, 22 months after the diagnosis of aortic dissection, the patient is doing well with a still functioning graft (creatinine, 377 μmol/L; modification of diet in renal disease-glomerular filtration rate, 15 mL/min), and without any other immunosuppression than low-dose steroids.
Electroconvulsive Therapy for Depression Comorbid With Myasthenia Gravis
Authors: Warren Mark B. , Elder Scott , Litchfield Norman P. 
Published: August 2017

Objectives
Myasthenia gravis (MG) is a rare but well-described autoimmune disease, which is sometimes comorbid with psychiatric illness. There have been several case reports describing the use of electroconvulsive therapy (ECT) for the treatment of core psychopathology in the context of MG. We sought to review the available published data on ECT in MG and add another case example to the literature.

Methods
We performed a PubMed search for relevant articles or case reports in English describing ECT in MG and summarized findings.

Results
We identified 7 published cases meeting our inclusion criteria in varying detail with different psychiatric presentations and different anesthetic and ECT technique approaches. In addition, we add our own case.

Conclusions
Based on the literature and our own clinical experience, ECT seems to be a safe option for the treatment of core psychopathology with comorbid MG as long as appropriate precautions are in place, particularly when choosing an anesthetic approach.
TaxMapper: An Analysis Tool, Reference Database and Workow for Metatranscriptome Analysis of Eukaryotic Microorganisms
Authors: Beisser Daniela , Graupner Nadine , Grossmann Lars , Timm Henning , Boenigk Jens , Rahmann Sven 
Published: August 2017

AbstractBackgroundHigh-throughput sequencing (HTS) technologies are increasingly applied to analyse complex microbial ecosystems by mRNA sequencing of whole communities, also known as metatranscriptome sequencing. This approach is at the moment largely limited to prokaryotic communities and communities of few eukaryotic species with sequenced genomes. For eukaryotes the analysis is hindered mainly by a low and fragmented coverage of the reference databases to infer the community composition, but also by lack of automated workflows for the task.ResultsFrom the databases of the National Center for Biotechnology Information and Marine Microbial Eukaryote Transcriptome Sequencing Project, 142 references were selected in such a way that the taxa represent the main lineages within each of the seven supergroups of eukaryotes and possess predominantly complete transcriptomes or genomes. From these references, we created an annotated microeukaryotic reference database. We developed a tool called TaxMapper for a reliably mapping of sequencing reads against this database and filtering of unreliable assignments. For filtering, a classifier was trained and tested on sequences in the database, sequences of related taxa to those in the database and randomly generated sequences. Additionally, TaxMapper is part of a metatranscriptomic Snakemake workflow developed to perform quality assessment, functional and taxonomic annotation and (multivariate) statistical analysis including environmental data. The workflow is provided and described in detail to empower researchers to easily apply it for metatranscriptome analysis of any environmental sample.ConclusionsTaxMapper shows superior performance compared to standard approaches, resulting in a higher number of true positive taxonomic assignments. Both the TaxMapper tool and the workflow are available as open-source code at Bitbucket under the MIT license:https://bitbucket.org/dbeisser/taxmapperand as a Bioconda package:https://bioconda.github.io/recipes/taxmapper/README.html.
Bank adoption of mobile banking: stakeholder perspective
Authors: Mullan Jennifer , Bradley Laura , Loane Sharon 
Published: August 2017

PurposeBank adoption of mobile banking globally remains sporadic. Factors influencing this remain under researched. The purpose of this paper is to explore drivers and barriers of bank adoption of mobile banking from a stakeholder perspective.Design/methodology/approachUsing diffusion of innovation (DOI), a mixed method study was conducted. Data were collected using blogging to inform a two-round modified Delphi study. The opinion of 72 members from six stakeholder industries was sought.FindingsThe results indicate that DOI theory is still applicable within mobile environments in helping to understand the diffusion of mobile banking. Key drivers of bank adoption were global mobile phone penetration, competitive advantage, customer convenience, strategic importance, customer demand, low perceived risk/security concerns and stakeholder partnerships. Findings suggest low levels of customer demand and lack of return on investment (ROI) are key barriers for banks. The findings have strategic implications for industry players highlighting the importance of mobile banking to maintain market share and customer relations. These influences will inform successful mobile banking strategies by raising awareness of major barriers.Originality/valueThis study concentrates on a bank/stakeholder perspective. It confirms that DOI theory is still applicable within mobile environments. It extends understanding of bank adoption providing useful information for all stakeholders. It has implications for banks regarding multi-channel banking and the motivators and challenges influencing its adoption.
Singing from North to South: Latitudinal variation in timing of dawn singing under natural and artificial light conditions
Authors: Da Silva Arnaud , Kempenaers Bart 
Published: August 2017

Abstract

Animals breeding at northern latitudes experience drastic changes in daily light conditions during the breeding season with decreasing periods of darkness, whereas those living at lower latitudes are exposed to naturally dark nights throughout the year. Nowadays, many animals are also exposed to artificial night lighting (often referred to as light pollution).

Animals strongly rely on variation in light levels to time their daily and seasonal behaviour. Previous work on passerine birds showed that artificial night lighting leads to earlier onset of dawn song. However, these studies were carried out at intermediate latitudes with more limited seasonal changes in daylength, and we still lack an understanding of the impact of artificial night lighting in relation to variation in natural light conditions.

We investigated the influence of natural and artificial light conditions on the timing of dawn singing in five common songbird species in each of three regions in Europe that differed in natural variation in daylength (northern Finland, 65°N; southern Germany, 48°N; southern Spain, 37°N). In each region, we selected five peri‐urban forest sites with and five without street lighting, and we recorded dawn singing at the beginning of the local breeding season.

Our results show that the earliest natural singers, that is, European robins (Erithacus rubecula) and common blackbirds (Turdus merula), started dawn singing earlier along with the natural increase in night brightness in Finland, with no additional effects of artificial night lighting. In contrast, the later singers, such as, great tits (Parus major), blue tits (Cyanistes caeruleus) and chaffinches (Fringilla coelebs), showed similar onsets of dawn song relative to sunrise across the season and similar effects of artificial night lighting at all latitudes.

Artificial night lighting affected great tits, blue tits and chaffinches even in northern Finland where nights became very bright. Proximate factors such as differential light sensitivities may explain why early singers showed more plastic behavioural responses to naturally and artificially bright nights. The maintenance of rhythmicity in the late singers during bright northern nights and under artificial night lighting may also be an adaptive response to predation risk or costs of sleep loss.
Temperature drives abundance fluctuations, but spatial dynamics is constrained by landscape configuration: Implications for climate‐driven range shift in a butterfly
Authors: Fourcade Yoan , Ranius Thomas , Öckinger Erik 
Published: August 2017

Abstract

Prediction of species distributions in an altered climate requires knowledge on how global‐ and local‐scale factors interact to limit their current distributions. Such knowledge can be gained through studies of spatial population dynamics at climatic range margins.

Here, using a butterfly (Pyrgus armoricanus) as model species, we first predicted based on species distribution modelling that its climatically suitable habitats currently extend north of its realized range. Projecting the model into scenarios of future climate, we showed that the distribution of climatically suitable habitats may shift northward by an additional 400 km in the future.

Second, we used a 13‐year monitoring dataset including the majority of all habitat patches at the species northern range margin to assess the synergetic impact of temperature fluctuations and spatial distribution of habitat, microclimatic conditions and habitat quality, on abundance and colonization–extinction dynamics.

The fluctuation in abundance between years was almost entirely determined by the variation in temperature during the species larval development. In contrast, colonization and extinction dynamics were better explained by patch area, between‐patch connectivity and host plant density. This suggests that the response of the species to future climate change may be limited by future land use and how its host plants respond to climate change. It is, thus, probable that dispersal limitation will prevent P. armoricanus from reaching its potential future distribution.

We argue that models of range dynamics should consider the factors influencing metapopulation dynamics, especially at the range edges, and not only broad‐scale climate. It includes factors acting at the scale of habitat patches such as habitat quality and microclimate and landscape‐scale factors such as the spatial configuration of potentially suitable patches. Knowledge of population dynamics under various environmental conditions, and the incorporation of realistic scenarios of future land use, appears essential to provide predictions useful for actions mitigating the negative effects of climate change.
Weed suppression greatly increased by plant diversity in intensively managed grasslands: A continental‐scale experiment
Authors: Connolly John , Sebastià Maria‐Teresa , Kirwan Laura , Finn John Anthony , Llurba Rosa , Suter Matthias , Collins Rosemary P. , Porqueddu Claudio , Helgadóttir Áslaug , Baadshaug Ole H. , Bélanger Gilles , Black Alistair , Brophy Caroline , Čop Jure , Dalmannsdóttir Sigridur , Delgado Ignacio , Elgersma Anjo , Fothergill Michael , Frankow‐Lindberg Bodil E. , Ghesquiere An , Golinski Piotr , Grieu Philippe , Gustavsson Anne‐Maj , Höglind Mats , Huguenin‐Elie Olivier , Jørgensen Marit , Kadziuliene Zydre , Lunnan Tor , Nykanen‐Kurki Paivi , Ribas Angela , Taube Friedhelm , Thumm Ulrich , De Vliegher Alex , Lüscher Andreas 
Published: August 2017

AbstractGrassland diversity can support sustainable intensification of grassland production through increased yields, reduced inputs and limited weed invasion. We report the effects of diversity on weed suppression from 3 years of a 31‐site continental‐scale field experiment.At each site, 15 grassland communities comprising four monocultures and 11 four‐species mixtures based on a wide range of species' proportions were sown at two densities and managed by cutting. Forage species were selected according to two crossed functional traits, “method of nitrogen acquisition” and “pattern of temporal development”.Across sites, years and sown densities, annual weed biomass in mixtures and monocultures was 0.5 and 2.0 t DM ha−1(7% and 33% of total biomass respectively). Over 95% of mixtures had weed biomass lower than the average of monocultures, and in two‐thirds of cases, lower than in the most suppressive monoculture (transgressive suppression). Suppression was significantly transgressive for 58% of site‐years. Transgressive suppression by mixtures was maintained across years, independent of site productivity.Based on models, average weed biomass in mixture over the whole experiment was 52% less (95% confidence interval: 30%–75%) than in the most suppressive monoculture. Transgressive suppression of weed biomass was significant at each year across all mixtures and for each mixture.Weed biomass was consistently low across all mixtures and years and was in some cases significantly but not largely different from that in the equiproportional mixture. The average variability (standard deviation) of annual weed biomass within a site was much lower for mixtures (0.42) than for monocultures (1.77).Synthesis and applications. Weed invasion can be diminished through a combination of forage species selected for complementarity and persistence traits in systems designed to reduce reliance on fertiliser nitrogen. In this study, effects of diversity on weed suppression were consistently strong across mixtures varying widely in species' proportions and over time. The level of weed biomass did not vary greatly across mixtures varying widely in proportions of sown species. These diversity benefits in intensively managed grasslands are relevant for the sustainable intensification of agriculture and, importantly, are achievable through practical farm‐scale actions.
Wisdom of Crowds: Cross‐Sectional Variation in the Informativeness of Third‐Party‐Generated Product Information on Twitter
Authors: TANG VICKI WEI 
Published: August 2017

ABSTRACTThis paper examines whether third‐party‐generated product information on Twitter, once aggregated at the firm level, is predictive of firm‐level sales, and if so, what factors determine the cross‐sectional variation in the predictive power. First, the predictive power of Twitter comments increases with the extent to which they fairly represent the broad customer response to products and brands. The predictive power is greater for firms whose major customers are consumers rather than businesses. Second, the word‐of‐mouth effect of Twitter comments is greater when advertising is limited. Third, a detailed analysis of the identity of the tweet handles provides the additional insights that the predictive power of the volume of Twitter comments is dominated by “the wisdom of crowds,” whereas the predictive power of the valence of Twitter comments is largely attributable to expert comments. Furthermore, Twitter comments not only reflect upcoming sales, but also capture an unexpected component of sales growth.
Resin foraging dynamics in Varroa destructor‐infested hives: a case of medication of kin?
Authors: Pusceddu Michelina , Piluzza Giannella , Theodorou Panagiotis , Buffa Franco , Ruiu Luca , Bullitta Simonetta , Floris Ignazio , Satta Alberto 
Published: August 2017

AbstractSocial insects have evolved colony behavioral, physiological, and organizational adaptations (social immunity) to reduce the risks of parasitization and/or disease transmission. The collection of resin from various plants and its use in the hive as propolis is a clear example of behavioral defense. For Apis mellifera, an increased propolis content in the hive may correspond to variations in the microbial load of the colony and to a downregulation of an individual bee's immune response. However, many aspects of such antimicrobial mechanism still need to be clarified. Assuming that bacterial and fungal infection mechanisms differ from the action of a parasite, we studied the resin collection dynamics in Varroa destructor‐infested honeybee colonies. Comparative experiments involving hives with different mite infestation levels were conducted in order to assess the amount of resin collected and propolis quality within the hive, over a 2‐year period (2014 and 2015). Our study demonstrates that when A. mellifera colonies are under stress because of Varroa infestation, an increase in the number of resin foragers is recorded, even if a general intensification of the foraging activity is not observed. A reduction in the total polyphenolic content in propolis produced in infested versus uninfested hives was also noticed. Considering that different propolis types show varying levels of inhibition against a variety of honey bee pathogens in vitro, it would be very important to study the effects against Varroa of two diverse types of propolis: from Varroa‐free and from Varroa‐infested hives.
Effect of Ingredients on the Quality of Gluten‐Free Sorghum Pasta
Authors: Palavecino Pablo Martín , Bustos Mariela Cecilia , Heinzmann Alabí María Belén , Nicolazzi Melani Solange , Penci María Cecilia , Ribotta Pablo Daniel 
Published: August 2017

AbstractSorghum is an underutilized cereal in human food production, despite its flour being a potential gluten‐free (GF) source in the development of several foods. Thus, the aim of the present investigation was to evaluate the effects and interactions of different ingredients on cooking quality and texture of GF pasta. Egg albumen (A), egg powder (E), xanthan gum (X), and pregelatinized corn starch (P) were used as ingredients, and Box‐Behnken experimental design was applied to study the effects of these ingredients on pasta cooking behavior, color, and texture attributes. Responses were fitted to a second order polynomial equation, and multivariable optimization was performed using maximization of general desirability. Next, optimal formulations were validated, compared with two commercial gluten‐free pastas by sensory evaluation, and finally, an industrial assay was carried out. Regression coefficients indicated that A and P improved cooking properties while A and E contributed the most to improving the pasta textural properties. As, X and P effects varied depending on the kind of sorghum flour used, the optimal formulations levels were different, but in both cases these models were satisfactory and capable of predicting responses. The industrial assay was carried out with white sorghum flour because it showed a higher acceptability in the sensory evaluation than brown sorghum flour pasta. This industrially made pasta resulted in slightly better cooking properties than the laboratory produced one, with the formulation adapting well to the conventional wheat pasta industrial process. Gluten‐free sorghum pasta was produced, showing good cooking and textural properties and being a suitable option for gluten‐sensitive individuals.