bluuebunny/crossref_metadata_2025_split huggingface dataset:
Controls of reburn severity vary with fire interval in the Klamath Mountains, California,USA
Authors: Grabinski Zawisza S. , Sherriff Rosemary L. , Kane Jeffrey M. 
Published: December 2017

AbstractOver the past few decades, the frequency and number of large fires has increased in the western United States following a paucity of fire activity in many forests during most of the 20th century. Areas of repeated burning are of particular interest for understanding where there may be qualitative shifts in fire severity and the ecological consequences related to ecosystem resilience and climate change. In the context of recent increases in fire activity, we evaluated the relative importance of potential factors contributing to reburn severity (fire severity in areas that have burned twice) from 1985 to 2012 in the Klamath Mountains ecoregion of California. A unique component of our study was the evaluation of different scales of analysis within the ecoregion. The variables prior burn severity (continuous relative difference‐normalized burn ratio values from 1 to 1300), time since fire, biophysical setting, and average monthly weather were evaluated using generalized additive models to identify the relative importance of factors related to reburn severity patterns for 28 individual repeat fires (>375 ha), shorter (<15 yr) and longer (≥19 yr) fire interval categories, and across all repeat fires combined (79,112 ha). We found that evaluation of all repeat fires combined had masked important trends occurring across individual reburn areas of study particularly when dominated by one or more large fires. Averaging the variance of reburn severity explained across individual reburn areas (equal representation) yielded more explanatory power of predictor variables compared to the composite of all reburn areas combined. Over the period of analysis, topographic controls were relatively consistent regardless of fire interval, but vegetation characteristics had a stronger relationship than weather on reburn severity at longer fire intervals compared to shorter intervals. Likewise, we found greater similarity between prior and reburn severity at longer fire intervals than at shorter fire intervals. Our results underscore the presence of a self‐reinforcing pattern of fire severity related to the biophysical setting in the Klamath Mountains ecoregion, but also highlight the importance of spatial and temporal scale of evaluation and the interactions of vegetation characteristics, time since fire, and fire weather on reburn fire severity.
Forecasting consequences of changing sea ice availability for Pacific walruses
Authors: Udevitz Mark S. , Jay Chadwick V. , Taylor Rebecca L. , Fischbach Anthony S. , Beatty William S. , Noren Shawn R. 
Published: December 2017

AbstractThe accelerating rate of anthropogenic alteration and disturbance of environments has increased the need for forecasting effects of environmental change on fish and wildlife populations. Models linking projections of environmental change with behavioral responses and bioenergetic effects can provide a basis for these forecasts. There is particular interest in forecasting effects of projected reductions in sea ice availability on Pacific walruses (Odobenus rosmarus divergens). Declining extent of summer sea ice in the Chukchi Sea has caused Pacific walruses to increase use of coastal haulouts and decrease use of more productive offshore feeding areas. Such climate‐induced changes in distribution and behavior could ultimately affect the status of the population. We developed behavioral models to relate changes in sea ice availability to adult female walrus movements and activity levels, and adapted previously developed bioenergetics models to relate those activity levels to energy requirements and the ability to meet those requirements. We then linked these models to general circulation model projections of future ice availability to forecast autumn body condition for female walruses during mid‐ and late‐century time periods. Our results suggest that as sea ice becomes less available in the Chukchi Sea, female walruses will spend more time in the southwestern region of that sea, less time resting, and less time foraging. Median forecasted autumn body masses were 7–12% lower in future scenarios than during recent times, but posterior distributions broadly overlapped and median forecasted seasonal mass losses (15–34%) were comparable to seasonal mass losses routinely experienced by other pinnipeds. These seasonal reductions in body condition would be unlikely to result in demographic effects, but if walruses were unable to rebuild endogenous reserves while wintering in the Bering Sea, cumulative effects could have implications for reproduction and survival, ultimately affecting the status of the Pacific walrus population. Our approach provides a general framework for forecasting consequences of the broad range of environmental changes and anthropogenic disturbances that may affect bioenergetics through behavioral responses or changes in prey availability.
Leaf litter additions enhance stream metabolism, denitrification, and restoration prospects for agricultural catchments
Authors: O'Brien Jonathan M. , Warburton Helen J. , Graham S. Elizabeth , Franklin Hannah M. , Febria Catherine M. , Hogsden Kristy L. , Harding Jon S. , McIntosh Angus R. 
Published: December 2017

AbstractGlobally intensive agriculture has both increased nitrogen pollution in adjacent waterways and decreased availability of terrestrially derived carbon frequently used by stream heterotrophs in nitrogen cycling. We tested the potential for carbon additions via leaf litter from riparian restoration plantings to act as a tool for enhancing denitrification in agricultural streams with relatively high concentrations of nitrate (1.3–8.1 mg/L) in Canterbury, New Zealand. Experimental additions of leaf packs (N = 200, mass = 350 g each) were carried out in 200‐m reaches of three randomly selected treatment streams and compared to three control streams receiving no additional leaf carbon. Litter additions increased ecosystem respiration in treatment streams compared to control streams but did not affect gross primary production, indicating the carbon addition boosted heterotrophic activity, a useful gauge of the activities of microbes involved in denitrification. Bench‐top assays with denitrifying enzymes using acetylene inhibition techniques also suggested that the coarse particulate organic matter added from leaf packs would have provided substrates suitable for high rates of denitrification. Quantifying denitrification directly in experimental reaches by open‐channel methods based on membrane inlet mass spectrophotometry indicated that denitrification was around three times higher in treatment streams where litter was added compared to control streams. We further assessed the potential for riparian plantings to reduce large‐scale downstream nitrogen losses through increasing in‐stream denitrification by modeling the effects of increasing riparian vegetation cover on nitrogen fluxes. Here, we combined estimates of in‐stream ecosystem processes derived from our experiment with a network model of catchment‐scale nitrogen retention and removal based on empirical measurements of nitrogen flux in this typical agricultural catchment. Our model indicated leaf inputs associated with increased riparian cover had the potential to double the catchment level rate of denitrification, offering a promising way to mitigate nitrate pollution in agricultural streams. Altogether, our study indicates that overcoming carbon limitation and boosting heterotrophic processes will be important for reducing nitrogen pollution in agricultural streams and that combining empirical approaches for predictions suggests there are large potential benefits from riparian re‐vegetation efforts at catchment scales.
Cenerimod, a novel selective S1P1 receptor modulator with unique signaling properties
Authors: Piali Luca , Birker‐Robaczewska Magdalena , Lescop Cyrille , Froidevaux Sylvie , Schmitz Nicole , Morrison Keith , Kohl Christopher , Rey Markus , Studer Rolf , Vezzali Enrico , Hess Patrick , Clozel Martine , Steiner Beat , Bolli Martin H. , Nayler Oliver 
Published: December 2017

AbstractSphingosine‐1‐phosphate receptor 1 (S1P1) modulators sequester circulating lymphocytes within lymph nodes, thereby preventing potentially pathogenic autoimmune cells from exiting into the blood stream and reaching inflamed tissues. S1P1 receptor modulation may thus offer potential to treat various autoimmune diseases. The first nonselective S1P1‐5 receptor modulator FTY720/fingolimod/Gilenya® has successfully demonstrated clinical efficacy in relapsing forms of multiple sclerosis. However, cardiovascular, hepatic, and respiratory side‐effects were reported and there is a need for novel S1P1 receptor modulators with better safety profiles. Here, we describe the discovery of cenerimod, a novel, potent and selective S1P1 receptor modulator with unique S1P1 receptor signaling properties and absence of broncho‐ and vasoconstrictor effects ex vivo and in vivo. Cenerimod dose‐dependently lowered circulating lymphocyte counts in rats and mice after oral administration and effectively attenuated disease parameters in a mouse experimental autoimmune encephalitis (EAE) model. Cenerimod has potential as novel therapy with improved safety profile for autoimmune diseases with high unmet medical need.
High‐Risk Palliative Care Patients’ Knowledge and Attitudes about Hereditary Cancer Testing and DNA Banking
Authors: Quillin John M. , Emidio Oluwabunmi , Ma Brittany , Bailey Lauryn , Smith Thomas J. , Kang In Guk , Yu Brandon J. , Owodunni Oluwafemi Patrick , Abusamaan Mohammed , Razzak Rab , Bodurtha Joann N. 
Published: December 2017

AbstractEven at the end of life, testing cancer patients for inherited susceptibility may provide life‐saving information to their relatives. Prior research suggests palliative care inpatients have suboptimal understanding of genetic importance, and testing may be underutilized in this clinical setting. These conclusions are based on limited research. This study aimed to estimate genetic testing prevalence among high‐risk palliative care patients in a National Cancer Institute‐designated comprehensive cancer center. We also aimed to understand these patients’ understanding of, and attitudes toward, hereditary cancer testing and DNA banking. Palliative care in‐patients with cancer completed structured interviews, and their medical records were reviewed. Among patients at high risk for hereditary cancer, we assessed history of genetic testing/DNA banking; and related knowledge and attitudes. Among 24 high‐risk patients, 14 (58.3%) said they/their relatives had genetic testing or they had been referred for a genetics consultation. Of the remaining 10 patients, seven (70%) said they would “probably” or “definitely” get tested. Patients who had not had testing were least concerned about the impact of future testing on their family relationships; two (20%) said they were “extremely concerned” about privacy related to genetic testing. Of patients without prior testing, five (50%) said they had heard or read “a fair amount” about genetic testing. No high‐risk patients had banked DNA. Overall, 23 (95.8%) said they had heard or read “almost nothing” or “relatively little” about DNA banking. Written materials and clinician discussion were most preferred ways to learn about genetic testing and DNA banking. Overall, this study demonstrates underutilization of genetics services at the end of life continues to be problematic, despite high patient interest.
Employee Anonymous Online Dissent: Dynamics and Ethical Challenges for Employees, Targeted Organisations, Online Outlets, and Audiences
Authors: Ravazzani Silvia , Mazzei Alessandra 
Published: December 2017

ABSTRACT:This article aims to enhance understanding of employee anonymous online dissent (EAOD), a controversial phenomenon in contemporary digital environments. We conceptualise and scrutinise EAOD as a communicative and interactional process among four key actors: dissenting employees, online outlet administrators, audiences, and targeted organisations. This multi-actor, dialectical process encompasses actor-related tensions that may generate unethical consequences if single voices are not brought out and confronted. Appropriating a Habermasian ethical and discursive lens, we examine and disentangle three particular challenges emerging from the EAOD process: lack of accountability and potential opportunism; equal participation and resolution of actor-related tensions; and organisational participation and internalisation of dissent. We show that EAOD can initiate plural dialogue that helps co-construct and balance different voices within an informal and noninstitutionalised context for interaction and public deliberation. We conclude our inquiry by offering reflections on practical implications and a research agenda for further investigation.
Evaluating mental health service use during and after emergency department visits in a multisite cohort of Canadian children and youth
Authors: Cappelli Mario , Cloutier Paula , Newton Amanda S. , Fitzpatrick Eleanor , Ali Samina , Dong Kathryn A. , Gray Clare , Kennedy Allison , Lyons John S. , Polihronis Christine , Rosychuk Rhonda J. 
Published: December 2017

AbstractObjectivesThe goal of this study was to examine the mental health needs of children and youth who present to the emergency department (ED) for mental health care and to describe the type of, and satisfaction with, follow-up mental health services accessed.MethodsA 6-month to 1.5-year prospective cohort study was conducted in three Canadian pediatric EDs and one general ED, with a 1-month follow-up post-ED discharge. Measures included 1) clinician rating of mental health needs, 2) patient and caregiver self-reports of follow-up services, and 3) interviews regarding follow-up satisfaction. Data analysis included descriptive statistics and the Fisher’s exact test to compare sites.ResultsThe cohort consisted of 373 children and youth (61.1% female; mean age 15.1 years, 1.5 standard deviation). The main reason for ED presentations was a mental health crisis. The three most frequent areas of need requiring action were mood (43.8%), suicide risk (37.4%), and parent-child relational problems (34.6%). During the ED visit, 21.6% of patients received medical clearance, 40.9% received a psychiatric consult, and 19.4% were admitted to inpatient psychiatric care. At the 1-month post-ED visit, 84.3% of patients/caregivers received mental health follow-up. Ratings of service recommendations were generally positive, as 60.9% of patients obtained the recommended follow-up care and 13.9% were wait-listed.ConclusionsChildren and youth and their families presenting to the ED with mental health needs had substantial clinical morbidity, were connected with services, were satisfied with their ED visit, and accessed follow-up care within 1-month with some variability.
Purely infinite labeled graph -algebras
Authors: JEONG JA A , KANG EUN JI , PARK GI HYUN 
Published: December 2017

In this paper, we consider pure infiniteness of generalized Cuntz–Krieger algebras associated to labeled spaces $(E,{\mathcal{L}},{\mathcal{E}})$. It is shown that a $C^{\ast }$-algebra $C^{\ast }(E,{\mathcal{L}},{\mathcal{E}})$ is purely infinite in the sense that every non-zero hereditary subalgebra contains an infinite projection (we call this property (IH)) if $(E,{\mathcal{L}},{\mathcal{E}})$ is disagreeable and every vertex connects to a loop. We also prove that under the condition analogous to (K) for usual graphs, $C^{\ast }(E,{\mathcal{L}},{\mathcal{E}})=C^{\ast }(p_{A},s_{a})$ is purely infinite in the sense of Kirchberg and Rørdam if and only if every generating projection $p_{A}$, $A\in {\mathcal{E}}$, is properly infinite, and also if and only if every quotient of $C^{\ast }(E,{\mathcal{L}},{\mathcal{E}})$ has property (IH).
Factors promoting and inhibiting sustained impact of a mental health task-shifting program for HIV providers in Ethiopia
Authors: Jerene D. , Biru M. , Teklu A. , Rehman T. , Ruff A. , Wissow L. 
Published: December 2017

Background.Task-shifting mental health into general medical care requires more than brief provider training. Generalists need long-term support to master new skills and changes to work context are required to sustain change in the face of competing priorities. We examined program and context factors promoting sustainability of a mental health task-shifting training for hospital-based HIV providers in Ethiopia.Methods.Convergent mixed-methods quasi-experimental study. Sustained impact was measured by trained/not-trained provider differences in case detection and management 16 months following the end of formal support. Factors related to sustainability were examined through interviews with trained providers.Results.Extent of sustained impact: Trained providers demonstrated modest but better agreement with standardized screeners (greater sensitivity with similar specificity). They were more likely to request that patients with mental health problems return to see them v. making a referral. Factors promoting sustainability (reported in semi-structured interviews): provider belief that the treatments they had learned were effective. New interactions with on-site mental health staff were a source of ongoing learning and encouragement. Factors diminishing sustainability: providers feelings of isolation when mental health partners left for work elsewhere, failure to incorporate mental health indicators into administrative data, to re-stock staff education materials, and to build formal mechanisms for generalist-mental health staff interaction.Conclusions.An intervention seen as feasible and effective, and promotion of relationships across professional lines, helped generalists sustain new skills. Failure to address key system context issues made use of the skills unsustainable as external supports ended.
Attending to adult ADHD: a review of the neurobiology behind adult ADHD
Authors: Alexander L. , Farrelly N. 
Published: December 2017

BackgroundAttention deficit hyperactivity disorder (ADHD) is a common disorder in childhood, which progresses to adulthood in about a fifth of cases. For various reasons, adult ADHD is a disorder not comprehensively assessed by psychiatrists, not least because the biological underpinnings are only recently being unmasked.AimsThis selective review targets psychiatrists without a background in neuroscience and aims to describe the neurobiological basis of ADHD.MethodsIn total, 40 articles from a PubMed search were selected for inclusion based on sample population and methodology (neuroimaging studies). Studies focussing on adult participants were selected preferentially for inclusion. Seminal articles relevant to childhood populations were included for the purpose of understanding general concepts around ADHD.ResultsThe neuropathology of ADHD is not rooted in a single anatomical area, but in multiple parallel and intersecting pathways, which have demonstrated impaired functional connectivity in ADHD brains. Dysfunction in executive function, reward processing, attention networks and default networks play major roles in the neuropathology of this condition. Biological findings vary between individuals, with some showing greater dysfunction at cortical levels and others at subcortical levels, which is in keeping with its clinical heterogeneity.ConclusionImproved symptomatology in adulthood is linked to a number of factors. Maturation of the prefrontal cortex in early adulthood contributes to symptom attenuation in many cases, meaning that individuals with cortical dysfunction are more likely to grow out of symptoms, whereas individuals with subcortical dysfunction may be less likely to do so. There is emerging evidence for a similar but distinct disorder arisingde novoin adulthood.
Motion Model and Speed Control of the Cross-Stream Active Mooring System for Tracking Short-Term Meandering to Maximize Ocean Current Power Generation
Authors: Tsao C. C. , Feng A. H. 
Published: December 2017

ABSTRACTThis paper analyzes the speed of lateral movement of the Cross-stream Active Mooring (CSAM) system in an ocean current and its control methods in order to study the system's capability of tracking short term meandering of ocean currents for maximizing power generation capacity. The CSAM concept for marine current power features a hydro sail system that can deploy generator turbines transversely across streams in a marine current. The hydro sail system can further adjust the horizontal position of the turbines, by changing the angle of attack of the hydro sail, to actively track fast streams in the marine current to increase power generation capacity. A two-step motion model with analytical formulas was developed and analysis based on mechanics indicated that the simplified model is adequate to estimate the system speed. Using an example system, it was estimated that the proposed active mooring system is capable of matching typical lateral speed of short term meandering and tracking fast streams in an ocean current without any external propulsion other than controlling the angle of attack of the hydro sails. Methods of controlling the system speed of moving from one location to another were also developed.
Analytical Study of Delamination in Multilayered Two-Dimensional Functionally Graded Non-Linear Elastic Beams
Authors: Rizov V. I. 
Published: December 2017

AbstractThe present paper is focused on the delamination fracture in a multilayered two-dimensional functionally graded beam configuration which exhibits non-linear behavior of the material. The beam is loaded by two longitudinal forces applied at the beam free ends. The beam contains a delamination crack which is located symmetrically with respect to the beam mid-span. The delamination is studied analytically in terms of the strain energy release rate. TheJ-integral approach is applied for verification of the analysis of the strain energy release rate. The solution derived is valid for a beam made of an arbitrary number of layers. It is assumed that each layer has individual thickness and material properties. Also, the material is two-dimensional functionally graded in the cross-section of each layer. The solution obtained can be applied for a delamination crack located arbitrary along the height of the beam cross-section. It is shown that the solution is very convenient for investigating the influences of material gradients and crack location on the delamination fracture behavior. The results obtained can be used for optimization of multilayered two-dimensional functionally graded structural members and components with respect to their delamination fracture performance.
Three Dimensional MHD Ferrous Nanofluid Flow Over a Sheet of Variable Thickness in Slip Flow Regime
Authors: Kumar R. , Raju C. S. K. , Sekhar K. R. , Reddy G. V. 
Published: December 2017

ABSTRACTIn the present paper, we analyzed the effects of magnetic field on the three dimensional flow of a nanofluid having the suspension of ferrous nano-particles within the framework of a non-uniformly thicked sheet in a slip flow regime. The sheet of variable thickness is assumed to be stretched in horizontal and transverse directions. The effects of thermophoretic forces and Brownian motion have also been incorporated into the governing equations. The RK-Fehlberg-integration scheme with shooting technique is employed to resolve the altered governing non-linear differential equations. Velocity, temperature and concentration profiles are presented and discussed for two cases namely uniform thickness stretching sheet UTSS (n = 1) and variable thickness stretching sheet VTSS (n ≠ 1), and skin friction coefficient, reduced Nusselt number and Sherwood number are computed and analyzed through tables. The results reveal that heat and mass transfer processes over slendering sheet matches with those over a flat sheet in the presence of slip flow regime.