bluuebunny/crossref_metadata_2025_split huggingface dataset:
KOMUNIKASI PEMASARAN DI HOTEL TAMAN SARI SUKABUMI (Studi Deskriptif Mengenai Komunikasi Pemasaran Terpadu Di Hotel Taman Sari Sukabumi)
Authors: Mira Renata  , Reihan Salsabila  
Published: September 2024

Salah satu kota di provinsi Jawa Barat yang menjadi daya tarik wisatawan untuk dikunjungi adalah Kota Sukabumi. Kota Sukabumi dikenal dengan kota yang bercuaca dingin dan memiliki sejumlah wisata yang dapat didatangi seperti wisata sejarah dan wisata kuliner. Dilihat dari insfrastuktur yang ada, kota ini cukup mengalami perkembangan yang signifikan di bidang pariwisata. Hal ini dapat dilihat dari banyaknya hotel-hotel, destinasi pariwisata dan juga restaurant-restaurant baik yang sudah lama berdiri maupun yang baru saja berdiri.
Dalam bisnis perhotelan, persaingan merupakan hal yang tidak dapat dihindari. Untuk mengantisipasi persaingan yang semakin ketat, industri perhotelan harus dapat lebih fokus terhadap kualitas dengan beberapa cara seperti dalam penggunaan teknologi yang efisien, produktif, dan mampu menjamin keunggulan mutu produknya. Selain itu pihak marketing hotel juga dapat melakukan strategi-startegi yang ada dalam komunikasi pemasaran. Hal-hal yang perlu diperhatikan dalam komunikasi pemasaran antara lain adalah segmentasi pasar, penentuan posisi pasar, strategi memasuki pasar, strategi penentuan waktu, dan strategi marketing mix. Terdapat beberapa elemen dalam strategi marketing mix yaitu produk (product), tempat (place), harga (price), dan promosi (promotion). Dimana kegiatan promosi tersebut dapat dilakukan melalui komunikasi pemasaran terpadu (Integrated Marketing Communication).
Measuring the Spot Variability of T Tauri Stars Using Near-infrared Atomic Fe and Molecular OH Lines
Authors: Tang Shih-Yun , Johns-Krull Christopher M. , Prato L. , Stahl Asa G. 
Published: September 2024

Abstract
As part of the Young Exoplanets Spectroscopic Survey, this study explores the spot variability of 13 T Tauri Stars (TTSs) in the near-infrared H band, using spectra from the Immersion GRating INfrared Spectrometer. By analyzing effective temperature (T
eff) sensitive lines of atomic Fe i at ∼1.56259 μm and ∼1.56362 μm, and molecular OH at ∼1.56310 and ∼1.56317 μm, we develop an empirical equivalent width ratio (EWR) relationship for T
eff in the range of 3400–5000 K. This relationship allows for precise relative T
eff estimates to within tens of Kelvin and demonstrates compatibility with solar metallicity target models. However, discrepancies between observational data and model predictions limit the extension of the T
eff–EWR relationship to a broader parameter space. Our study reveals that both classical and weak-line TTSs can exhibit T
eff variations exceeding 150 K over a span of 2 yr. The detection of a quarter-phase delay between the EWR and radial velocity phase curves in TTSs indicates spot-driven signals. A phase delay of 0.06 ± 0.13 for CI Tau, however, suggests additional dynamics, potentially caused by planetary interaction, inferred from a posited 1:1 commensurability between the rotation period and orbital period. Moreover, a positive correlation between T
eff variation amplitude and stellar inclination angle supports the existence of high-latitude spots on TTSs, further enriching our understanding of stellar surface activity in young stars.
PyDwCA: A Tool for Integrating Biodiversity Data
Authors: Sáez-Hidalgo Juan , Segovia Ricardo , Squeo Francisco , Guerrero Pablo 
Published: September 2024

The Darwin Core Archive (DwC-A) format, based on the Darwin Core standard (Wieczorek et al. 2012), facilitates the exchange, management, and integration of biodiversity data from multiple sources. This ability to collate biodiversity data allows datasets to be aggregated at community-supported infrastructures, merged in different combinations, meta-analyzed and submitted to public repositories (Baker et al. 2014). Thus, the DwC-As serve as unifying archives in concatenated collective efforts, such as biodiversity inventories at different spatial and taxonomic scales.
Here we describe PyDwCA*1, 2, a Python library implemented to handle the "star scheme" of DwC-A. This new library reads compressed zip files containing the expected meta.xml and uses it to assign the core component and its extensions. It also provides Python classes to define the core, the extensions, and the metadata file for creating an archive and writing it into a compressed zip file. PyDwCA also implements functionality to select, filter and merge DwC-A files.
We present this new tool in the context of the construction of the Chilean National Biodiversity Inventory (Fig. 1), but PyDwCA serves as a versatile technical solution applicable to different contexts in the field of biodiversity informatics (e.g., integration of datasets from biological collection and sampling events). To exemplify how PyDwCA works, we present the step-by-step integration of the Chilean Catalogue of Vascular Plants (Rodriguez et al. 2018) on a matrix provided by the Catalogue of Life (Banki 2024), filtered with the species with occurrences recorded for Chile in the Global Biodiversity Information Facility (GBIF) (GBIF.Org 2023).
Smart healthcare: developing a pattern to predict the stress and anxiety among university students using machine learning technology
Authors: Lotfi Farhad , Rodić Branka , Labus Aleksandra , Bogdanović Zorica 
Published: September 2024

Background: Anxiety among students has become a fairly major problem. In the current era, Machine Learning (ML) can be used as a quick technology to predict students&#39; anxiety with the high-level accuracy.&nbsp;
Objectives: This research aims to predict university students&#39; anxiety by using supervised learning algorithms with providing pertinent feedback.&nbsp;
Methods: A total of 231 students from the University of Belgrade filled out the standard questionnaire called the State-Trait Anxiety Inventory (STAI). In addition, deeper information related to students&rsquo; anxiety like physical activity, Grade Point Average (GPA), and smoking cigarettes were collected. The Linear Regression algorithm was chosen to examine STAI using Python. &nbsp;
Results: Linear regression as an appropriate algorithm was exploited for this purpose. The accuracy metric obtained by using the Mean Absolute Error (MAE), was 7.86 for state anxiety and 5.68 for trait anxiety. In addition, the Mean Squared Error (MSE) has also been calculated with state anxiety at 7.80, and trait anxiety at 9.66. Moreover, to find the factor with the highest impact after training, a regression analysis method (LASSO) was used. K-Nearest Neighbour (KNN) algorithm also checked the accuracy of training by overfitting and underfitting.&nbsp;
Conclusion: The purpose of this study was the analysis of anxiety factors with the highest impact as well as the analysis of the STAI by linear regression to improve a smart healthcare model by discovering an acceptable output with the highest accuracy. &nbsp;
Morphologic Response in Femoral Cartilage During and After 40-Minute Treadmill Running
Authors: Lee Jinwoo , Lim Junhyeong , Park Sanghyup , Kim Sojin , Park Jihong 
Published: September 2024

Context
It is unclear whether the response in femoral cartilage to running at different intensities is different.

Objective
To examine the acute patterns of deformation and recovery in femoral cartilage thickness during and after running at different speeds.

Design
Crossover study.

Setting
Laboratory.

Patients or Other Participants
A total of 17 healthy men (age = 23.9 ± 2.3 years, height = 173.1 ± 5.5 cm, mass = 73.9 ± 8.0 kg).

Intervention(s)
Participants performed a 40-minute treadmill run at speeds of 7.5 and 8.5 km/h.

Main Outcome Measure(s)
Ultrasonographic images of femoral cartilage thickness (intercondylar, lateral condyle, and medial condyle) were obtained every 5 minutes during the experiment (40 minutes of running followed by a 60-minute recovery period) at each session. Data were analyzed using analysis of variance and Bonferroni- and Dunnett-adjusted post hoc t tests. To identify patterns of cartilage response, we extracted principal components (PCs) from the cartilage-thickness data using PC analysis, and PC scores were analyzed using t tests.

Results
Regardless of time, femoral cartilage thicknesses were greater for the 8.5-km/h run than the 7.5-km/h run (intercondylar: F1,656 = 24.73, P &lt; .001, effect size, 0.15; lateral condyle: F1,649 = 16.60, P &lt; .001, effect size, 0.16; medial condyle: F1,649 = 16.55, P &lt; .001, effect size, 0.12). We observed a time effect in intercondylar thickness (F20,656 = 2.15, P = .003), but the Dunnett-adjusted post hoc t test revealed that none of the time point values differed from the baseline value (P &gt; .38 for all comparisons). Although the PC1 and PC2 captured the magnitudes of cartilage thickness and time shift (eg, earlier versus later response), respectively, t tests showed that the PC scores were not different between 7.5 and 8.5 km/h (intercondylar: P ≥ .32; lateral condyle: P ≥ .78; medial condyle: P ≥ .16).

Conclusions
Although the 40-minute treadmill run with different speeds produced different levels of fatigue, morphologic differences (&lt;3%) in the femoral cartilage at both speeds seemed to be negligible.
Self-care practices among professional nurses employed in primary health care clinics
Authors: Nkabinde-Thamae George J. , Downing Charlene 
Published: September 2024

Background: Professional nurses typically promote and advocate self-care practices to their patients to achieve better health outcomes, but rarely engage in these practices themselves.Methods: A qualitative, descriptive phenomenological approach was used in this study. Ten professional nurses employed in different primary health care facilities were purposively sampled. Semi-structured interviews were conducted to collect data, which were analysed using Colaizzi’s data analysis strategy, and data saturation was reached.Results: Two themes were identified. Theme 1: the participants expressed that internal and external factors compromised self-care practices, such as subconscious self-neglect, insufficient resources, and a depressed economy, which encouraged them to work extended hours. Theme 2: participants’ holistic well-being was compromised, as they neglected their mental well-being.Conclusion: Self-care practices among professional nurses seem unachievable. The extent of this population’s self-care neglect was evident during the coronavirus disease 2019 (COVID-19) pandemic when professional nurses globally gave of themselves relentlessly.Contribution: This is the first study conducted on the topic in the City of Ekurhuleni, and the findings will provide relevant stakeholders with a directive on what strategies, policies, and guidelines to develop and implement to make self-care practices attainable for professional nurses.
Use of Electroconvulsive Therapy in a Patient with a Permanent Cardiac Pacemaker
Authors: Grover Sandeep , Jagota Gopika , Swer Sankie B. 
Published: September 2024

AbstractThere is limited information on the use of electroconvulsive therapy (ECT) in patients having a cardiac pacemaker. The aim of the study was to present a case of an older woman with an implanted permanent cardiac pacemaker who presented with recurrent catatonia in the background of recurrent depressive disorder, a current episode of severe depression with psychotic symptoms, and managed with ECT. A 65-year-old female patient presented with catatonia in the background of severe depression with psychotic symptoms and marked cachexia to the emergency services for management of catatonia. Initially, she was managed with lorazepam, with which she showed improvement in catatonia. However, after 2 weeks, there was a worsening of catatonia and resultantly she was considered for ECT. In addition, she was treated with venlafaxine 150 mg/day and olanzapine 5 mg/day. She maintained well for a year, she again developed depressive, psychotic symptoms, suicidal ideations, and catatonic symptoms in the form of mutism, rigidity, negativism, and staring. Her medications were increased to tablet escitalopram 20 mg/day and tablet olanzapine 10 mg/day, but her symptoms kept worsening. The lorazepam challenge test done during this time was negative, and she was readmitted to the inpatient unit. Her medications were changed to tablet dosulepin, and she again received 15 effective ECTs. The patient was discharged on tablet dosulepin 112.5 mg/day and olanzapine 10 mg/day and maintained well for the next 6 months, i.e., until the last follow-up. ECT can be given safely in patients with depression having cardiac pacemakers with close monitoring of the cardiac parameters during ECT.
Unraveling the Spectrum of Deliberate Self-harm and Survivors of Suicide
Authors: Ramanathan Barath , Vijayan Souganya , Sivakumar Perarul , Selvaraj Arun 
Published: September 2024

Abstract

Introduction:
Among people who attempt suicide, some may have intent to die and some may not. At present, there are not many studies that have compared clinical profiles based on the intent of the attempt of suicide, i.e., low-intent group (deliberate self-harm [DSH]) and high-intent group (suicide survivors). Our study aims to compare the psycho-socio-demographic profile between DSH and suicide survivors.

Materials and Methods:
It was a cross-sectional study. A total of 100 patients were recruited for the study. The data were collected on sociodemographic variables, psychiatric disorders, suicide intent, anxiety, and depression. Grouping was done using Beck’s suicide intent as the determining dimension. The DSH and suicide survivors were defined by the psycho-socio-demographic characteristics of the patients.

Results:
Two groups with different traits emerged in aspects of age, gender, education, occupation, employment, residence, method of attempts, family history of suicide, physical illness, psychiatric diagnosis, well-being, hopelessness, depression, and anxiety scores, which showed statistically significant difference (P < 0.05) in the study.

Conclusions:
DSH and suicide survivors exhibit notable distinctions in their psycho-socio-demographic and clinical profiles.
The Impact of Intraoperative Hyperlactatemia on Weaning from Cardiopulmonary Bypass in Patients Undergoing on-Pump Coronary Artery Bypass Grafting Surgery: An Observational Study
Authors: Tawadros Pierre Zarif , Mustafa Mahmoud Mohamed , Ibrahim Amr Abdelmonem , El-Masry Hadi , Al-Tantawy Mostafa A. 
Published: September 2024

Abstract

Background:
Hyperlactatemia after cardiac surgery is common. However, the association and the implications of hyperlactatemia on the prognosis after cardiopulmonary bypass (CPB) remains controversial. This study investigated the associations between early-onset hyperlactatemia and the need for doses of inotropes and vasopressors during weaning from CPB, hemodynamic stability after weaning from CPB, and the duration of postoperative mechanical ventilation.

Patients and Methods:
This prospective cohort study included 300 patients who underwent elective on-pump coronary artery bypass grafting (CABG) surgery and had normal systolic function >55%. Serum lactate levels were measured 1 h before induction, upon initiation of CPB, after removal of aortic cannula and on admission to the intensive care unit (ICU). Patients were divided into two groups: patients with lactate levels <4 mmol/L (Group N) and those with lactate levels ≥4 mmol/L (Group H).

Results:
Patients with hyperlactatemia constituted 20.7% of the study population. The number of patients who required adrenaline and noradrenaline administration upon weaning from CPB, as well as the doses of these drugs, were significantly higher in Group H (P < 0.001). Arterial blood pressure levels after weaning from CPB and upon admission to the ICU were significantly lower in Group H patients (P < 0.001). The duration of post-operative mechanical ventilation was longer in Group H patients (P < 0.001).

Conclusion:
Early-onset hyperlactatemia was associated with worse outcomes after CABG surgery. There was difficult weaning from CPB with increased inotrope and vasopressor drug support, early post-operative hemodynamic instability, and a prolonged duration of post-operative mechanical ventilation.
Establishment and validation of glioma patient-derived organoid models
Authors: Wang Anqi , Xie Xiangtong , Hao Lu , Li Xuetao , Huang Yulun , Wang Zhimin 
Published: September 2024

Abstract

Background and Aim:
Glioma is one of the most prevalent and refractory brain cancers with a high recurrence rate. Current limitations of experimental in vitro models include their inability to remodel the heterogeneity of the parental tumors and their incapacity to effectively reflect antitumor effects and mechanisms observable in vivo. Organoid models, as a new technology developed in recent years, can preserve the histological characteristics, cellular diversity, and gene expression of parental tumors to the fullest extent, thereby delivering more reliable data. This study intends to construct a simple organoid model developed from glioma patient material.

Materials and Methods:
Glioma samples were taken intraoperatively and cultured in the organoid medium using a continuous horizontal shaker. Sample collection and scientific research were authorized and approved by the Ethics Committee of Kowloon Hospital, China (Approval No. KY-2021-007). Immunofluorescence was applied to identify CD31 and Sox2 protein expression in the organoid model. The differences between primary glioblastomas and transplanted organoid tumors were analyzed by hematoxylin and eosin (H and E) staining. Immunohistochemistry (IHC) and Western blot assay were used to analyze the Sox2, Ki67, and CD31 protein expression levels.

Results:
The success rate of establishing organoid models was 90.9% in the primary glioblastomas, 75.0% in the WHO Grade III gliomas, and 42.9% in the Grade I–II gliomas. Immunofluorescence demonstrated that in vitro cultured organoids expressed CD31 and Sox2. Similarly, IHC and Western blot assay showed that orthotopically transplanted organoid tumors could exhibit high expressions of Sox2, Ki67, and CD31. There were no significant differences regarding the pathological features of primary glioblastomas and glioma organoid model as judged by H and E staining.

Conclusions:
This study presents a simple in vitro organoid model established from glioma patient samples. The success rate of constructing an organoid model is correlated with the degree of glioma malignancy. The established organoid model displays original model properties and simplifies the development of new experimental platforms that can support preclinical glioma treatment studies.
Role of Steroids in Paint Thinner Induced Chemical Pneumonitis
Authors: Indhu S , Kalaimani S , Harish Sabarigrivasan , Ramalingam Gogulakrishnan 
Published: September 2024

Abstract
Paint thinners are organic hydrocarbons that contain a mixture of chemicals such as acetone, toluene, and xylene. Thinner poisoning is most common in children due to accidental ingestion. Acute poisoning can lead to various systemic manifestations such as chemical pneumonitis, arrhythmia, dermatitis, and metabolic acidosis. Chronic toxicity leads to encephalopathy and weakness. Usually, management of chemical pneumonitis following hydrocarbon aspiration is symptomatic and the role of steroids is controversial. We report the case of a 47-year-old female who presented with ingestion of paint thinner with suicidal intention and developed chemical pneumonitis. She was initially managed symptomatically but due to persistent symptoms, was started on intravenous steroids and antibiotic. The patient showed symptomatic and radiological resolution.
Correlation between Respiratory Symptoms Questionnaire and Pulmonary Function Test in Chronic Obstructive Lung Disease Patients: A Tertiary Care Hospital Study
Authors: Chandrasekaran Srinidhi , Sreenivasan Vadivelu , Verma Ghanshyam 
Published: September 2024

Abstract

Objective:
This study aimed to investigate the correlation between respiratory symptoms assessed by the Respiratory Symptoms Questionnaire (RSQ) and pulmonary function test (PFT) results in patients diagnosed with chronic obstructive pulmonary disease (COPD) at a tertiary care hospital.

Methods:
This analytical, cross-sectional study was conducted at Sree Balaji Medical College and Hospital, Chennai, involving 130 COPD patients presenting with symptoms of breathlessness, chronic cough, and wheeze. Data collection instruments used were: (1) RSQ: The RSQ was utilized to assess respiratory symptoms, including breathlessness, cough, and wheeze, (2) PFT: PFT assessments, including spirometry, were performed to measure lung function impairment objectively. Participants completed the RSQ under supervision, followed by PFT assessments conducted by trained respiratory technologists using standardized procedures.

Results:
Descriptive statistics were computed for demographic variables and questionnaire scores. Pearson correlation analysis was employed to assess the association between respiratory symptoms measured by RSQ and PFT parameters. The Chi-square analysis determined the overall association between symptom scores and PFT results across the COPD severity groups. Significant correlations were observed between severe COPD and St. George’s Respiratory Questionnaire, moderate COPD and Clinical COPD Questionnaire, and moderate-to-severe COPD and COPD Assessment Test (P < 0.05). Nonsignificant correlations were found between mild COPD and symptom scores (P > 0.05). The Chi-square analysis confirmed a strong association between respiratory symptoms and PFT results (P = 0.04).

Conclusion:
This study highlights the importance of comprehensive symptom assessment alongside the objective measures of lung function in COPD management. Integrating tools such as RSQ with PFTs enables clinicians to obtain a holistic understanding of patients’ disease status and tailor treatment strategies accordingly.
Impact of Mild Gestational Diabetes Mellitus on Maternal and Fetal Liver Histopathological Alterations
Authors: Khales Sahar Ardalan , Mafinezhad Asghar , Golalipour Masoud , Roshandel Gholamreza , Ghafari Soraya , Golalipour Mohammad Jafar 
Published: September 2024

Background:
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications that can affect the organ systems of the body in both the mother and fetus. This study aimed to determine the impact of mild GDM on maternal and fetal liver histopathological alterations.

Materials and Methods:
In this experimental study, 20 pregnant Wistar rats were randomly allocated in control and diabetic groups. Mild hyperglycemia was induced by intraperitoneal injection of streptozotocin (40 mg/kg body weight) on the 5th day of gestation. The control group received an equal volume of citrate buffer. The diabetic state was confirmed by a blood glucose level of 120–300 mg/dL. Maternal and fetal liver samples were obtained on day 19 of gestation and stained with hematoxylin and eosin for histopathological investigation.

Results:
Liver sections of diabetic dams exhibited edematous hepatocytes and scattered pyknotic and necrotic cells with dilated sinusoids and congested central veins. The portal tracts showed the proliferation of bile ducts with mild chronic inflammatory cells infiltrating together with fibrosis beyond the limited plate which extends to the central vein (porto-central fibrosis). Liver sections of their fetuses revealed edematous hepatocytes with increased necrotic cells, with pyknotic nuclei, dilatation of the hepatic sinusoids, and their central veins. There was also a relative increase in megakaryocytes, which promoted fibrosis and distorted vascular beds of the hepatic tissue. The portal tracts also showed bile duct proliferation.

Conclusion:
This study highlighted the adverse effects of uncontrolled mild GDM on liver structure in rat dams and their fetuses.