bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social entrepreneurial ecosystems in Euroregions
Authors: Wevers Herman Theodoor , Voinea Cosmina Lelia , Curseu Petru Lucian 
Published: September 2024

Purpose
The purpose of this paper is to extend the knowledge of social entrepreneurial ecosystems and test their effect on social entrepreneurial activity in a cross-border context.

Design/methodology/approach
The current research used the fuzzy set Qualitative Comparative Analysis method on a sample of 4,357 cross-border cooperation (CBC) projects implemented between 2014 and 2020, spread over 40 Euroregions.

Findings
Single ecosystem elements can be sufficient conditions but with a limited effect on cross-border social entrepreneurship. Configurations of ecosystem elements can be necessary conditions with synergetic effects. A geographical pattern was identified in the spread of configurations across Europe.

Research limitations/implications
Geographical, quantitative and project data constraints exist. The authors call for research into synergies between ecosystem elements in cross-border contexts and ecosystem patterns across Europe.

Practical implications
Policymakers, their cross-border counterparts and Euroregions could coordinate their efforts to improve ecosystems’ impact and involve social entrepreneurs to scale impact in neighboring countries.

Social implications
Involving social entrepreneurs in CBC projects will show how social impact in one country can be valuable for solving issues in the neighboring country. This will increase the valuation of innovative solutions, create opportunities for scaling social impact and contribute to the European (EU) Cohesion Policy.

Originality/value
The study uses a novel approach by investigating the effect of social entrepreneurial ecosystems in Euroregions on social entrepreneurial activity in a cross-border context. The study shows that the impact of social entrepreneurial ecosystems does not stop at the country’s borders.
Differentiating three distinct kinds of flaws in oil and gas pipelines derived from the spacing effect of capacitive imaging sensors
Authors: Li Zhen , Han Jianqing , Cao Renting , Wang Yanzhe , Zhang Cong , Chang Lin , Zhang Yongbo , Zhang Hongyuan 
Published: September 2024

Purpose
This paper aims to apply the spacing effect of capacitive imaging (CI) sensors to inspect and differentiate external flaws of the protective module, internal flaws of the protective module and external flaws of the metallic module in oil and gas pipelines simultaneously. Through experimental verification, a method for differentiating three distinct kinds of flaws derived from the spacing effect of CI sensors has been demonstrated.

Design/methodology/approach
A 3Dimensions (3D) model for simulating the inspection of these flaws was established by using COMSOL. A novel CI sensor with adjustable working electrode spacing was designed, and a modular CI system was developed to substantiate the theoretical findings with experimental evidence. A method for differentiating three distinct kinds of flaws derived from the spacing effect of CI sensors was established.

Findings
The results indicate that the method can successfully discriminate external flaws of the protective module, internal flaws of the protective module and external flaws of the metallic module using CI sensors.

Originality/value
The method for differentiating three distinct kinds of flaws derived from the spacing effect of CI sensors is vital for keeping the transportation safety of oil and gas pipelines.
Analysis of neuraminidase activity of human parainfluenza viruses using enzyme‐linked lectin assay and BTP3‐Neu5Ac assay
Authors: Yang Jie , Kisu Tomoko , Watanabe Oshi , Kitai Yuki , Ohmiya Suguru , Fan Yuxuan , Nishimura Hidekazu 
Published: September 2024

AbstractHuman parainfluenza viruses (hPIVs) are causative agents of upper and lower respiratory tract infections and they have four serotypes. The virion surface displays hemagglutinin‐neuraminidase (HN), having hemagglutinating (HA) and neuraminidase (NA) activities in a single molecule. The HA activity binds the virion to sialic acid on the viral receptor on host cells and the NA releases the progeny viruses from the cell surface. There are several methods for assaying viral NA activity, such as the thiobarbituric acid assay, 4‐methylumbelliferyl‐N‐acetyl‐α‐d‐neuraminic acid assay, NA‐Star assay, and enzyme‐linked lectin assay (ELLA). However, these are mainly used for influenza viruses and not for hPIVs. A fluorescent‐based cytochemical NA assay using BTP3‐Neu5Ac as the substrate was recently developed and used for orthomyxo‐ and paramyxoviruses, including types 1 and 3 hPIVs. In this study, we used the ELLA, and BTP‐Neu5Ac assay for 14 field isolate strains of hPIVs including all four serotypes. The reaction in ELLA at pH 6.5 using peanut agglutinin (PNA) as a lectin was very low for all tested viruses except a type 3 virus strain with the maximum reaction at pH 6.5 and the acidic conditions did not enhance the reaction. ELLA with another lectin, Erythrina cristagalli agglutinin exhibited significant and stronger reactions than with PNA in some strains of types 1 and 3 viruses. The BTP3‐Neu5Ac assay showed a fluorescent signal on cells infected with all the viruses except the hPIV1/Sendai/713/2018 strain in LLC‐MK2 and/or MNT‐1. The signal was detected in cell‐free virus, as well, in all the viruses except the hPIV4a/Sendai/3935/2003 strain. The strength of the signal varied among viral strains but it was stronger in the reaction at pH 4.0 than pH 7.0 and strongest in type 2 hPIVs.
Prestack reservoir prediction method in ray parameter domain based on wide azimuth ocean bottom node seismic data
Authors: Jiangbo Huang , Jun Ming , Jianli Wang , Tongxing Xia , Chuanqi Liu 
Published: September 2024

AbstractWide azimuth seismic data play an important role in deep reservoir prediction. According to the Paleogene clastic rock reservoir prediction, the high‐density and wide azimuth 3D seismic data acquisition of ocean bottom nodes was first carried out in a Chinese offshore oilfield in 2019. After high precision amplitude‐preserving processing, we obtained the high‐quality wide azimuth gathers. However, the research on anisotropy and reservoir prediction using wide azimuth seismic data mainly focuses on carbonate and bedrock intervals, which is not suitable for clastic rock reservoir prediction. Therefore, this paper innovatively proposes a clastic rock reservoir prediction method, which studies prestack reservoir prediction in the ray parameter domain based on wide azimuth ocean bottom node seismic data. Based on the azimuth gathers, we can obtain elastic parameters through prestack amplitude versus offset inversion, which is used to characterize the reservoir, so it is significant to obtain high precision elastic parameters in order to get highly reliable reservoir prediction results. In this paper, we develop an amplitude versus offset inversion method based on the Bayesian theory in ray parameter domain, the output of which is density, P‐wave impedance and Vp/Vs. These elastic parameters have high precision, and density data are valuable input for reservoir characterization because they are sensitive to the lithology of clastic rock reservoir at different orientations. In ray parameter domain inversion, the ray path of seismic wave propagation is considered polyline, which is more consistent with the actual situation; thus, extracted amplitudes of P gathers used in inversion are more accurate. In addition, the reflection coefficient formula in ray parameter domain has higher precision when the incident angle is large. The inversion based on the Bayesian theory can improve the stability of the inversion. Test on the actual data shows that the result of ray parameter domain inversion with a Bayesian scheme is more accurate, stable and reliable. Based on the above high precision density inversion results, an innovative wide azimuth data reservoir prediction technology based on elliptical short‐axis fitting was proposed. The actual prediction of the deep reservoir in the Bohai oilfield shows that sand thickness fitting prediction results in the short axis can best match the actual drilling sandstone thickness. The coincidence rate is 86% and the short‐axis fitting results are more in agreement with geological laws. Theoretical research and practical applications have shown that this method is feasible and effective, with high prediction accuracy, computational efficiency and strong application value.
Court Disclosures of Firms in Chapter 11 Bankruptcy
Authors: Bastiaansen Ilona , Lerman Alina , Murphy Frank , Vyas Dushyant 
Published: September 2024

ABSTRACTStakeholders in the Chapter 11 reorganization process face significant information uncertainty about the post‐emergence prospects of the firm. The U.S. Bankruptcy Code requires a debtor to provide a disclosure statement containing “adequate information” about its financial status and a proposed reorganization plan but stops short of rigidly defining the adequacy standard. We document the heterogeneity in disclosure statement information across 16 distinct attributes and examine the variation in disclosures along several dimensions that reflect agency costs and coordination problems. We observe that Chapter 11 disclosure correlates more with claimant‐ and case‐specific characteristics than pre‐bankruptcy debtor characteristics. Our results illustrate the importance of institutional features in specific disclosure settings such as bankruptcy court filings. The research questions and methods of this study were registered via the Journal of Accounting Research’s registration‐based editorial process.
Molecular characterization and immune association of Fas‐associated death domain protein (FADD) in Tenebrio molitor
Authors: Yun Keunho , Jang Ho Am , Patnaik Bharat Bhusan , Hwang Su Hyeon , Lee Yong Seok , Han Yeon Soo , Jo Yong Hun 
Published: September 2024

AbstractFas‐associated death domain protein (FADD) is an apoptotic adapter molecule that recruits caspases and facilitates the formation of death‐inducing signaling complexes in mammals. In lower animals, FADD forms a complex with immune deficiency and death‐related ced‐3/Nedd2‐like caspase to elicit antimicrobial responses. In this study, we characterized the FADD sequence of Tenebrio molitor (TmFADD) using molecular informatics to understand its role in immune surveillance of the host against microorganisms. The 618 bp open reading frame of TmFADD encodes a polypeptide of 204 amino acids. The protein includes two promiscuous domains, the death‐effector domain and the death domain, found at the N‐ and C‐termini, respectively. TmFADD is clustered with the coleopteran FADD sequences in the phylogenetic tree. Homology‐based structural analysis showed an α‐helical model with a QMEAN score of 0.58. The expression of TmFADD mRNA was conspicuous in the larval and early pupal stages. TmFADD mRNA was distributed in the immune tissues of the larva and was found predominately in the gut of the adult. Infection of the host with Candida albicans, Escherichia coli or Staphylococcus aureus increased the expression of TmFADD mRNA, suggesting that these microorganisms trigger the innate immunity of the host. The silencing of TmFADD transcripts resulted in an increased susceptibility of T. molitor larvae to infection with E. coli, but not to infection with C. albicans or S. aureus. Hence, these results indicate that FADD plays a role in the defense of T. molitor and could open avenues for understanding insect immunity.
Chemical composition and mosquitocidal potential of Gloriosa superba (flame lily) seed extract against the dengue mosquito Aedes aegypti and aquatic mosquito predators
Authors: Ramasamy Venkatachalam , Prakash Palanisamy , Vasantha‐Srinivasan Prabhakaran , Han Yeon Soo , Karthi Sengodan , Senthil‐Nathan Sengottayan , Gayathiri Ekambaram , Park Ki Beom , Umavathi Subramaniam 
Published: September 2024

AbstractThis study investigates the mosquitocidal potential of crude petroleum ether extract fractions derived from Gloriosa superba against the dengue mosquito vector Aedes aegypti. Chemical profiling through gas chromatography identified four major metabolites, with nonadecane showing the highest peak area percentage (70.34%). A lethal dosage of fraction IV of G. superba (Gs‐F4), at a maximum concentration of 5.0 ppm, exhibited high mortality rates in second (78%), third (71%) and fourth (51%) instars of Ae. aegypti. A sublethal dosage of Gs‐F4 (3.0 ppm) significantly altered the larval midgut enzymes of cytochrome P450, esterases and glutathione S‐transferases. The repellent activity of Gs‐F4 was dosage dependent, with repellency percentages decreasing from 96% to 50% as the exposure time increased from 15 to 210 mins. The impact of Gs‐F4 on aquatic mosquito predators was marginally toxic (<50%) compared with the commercial compound temephos (1.0 ppm), which exhibited a higher toxicity (>50%). In silico toxicity screening using the BeeToxAI server indicated that three of the four compounds in Gs‐F4 were safe or non‐toxic to honeybees, except for α‐gurjunene (6.29 μg/bee). Although G. superba demonstrates effective larvicidal and repellent activity against Ae. aegypti, the non‐target toxicity against mosquito predators necessitates further toxicological screening on beneficial species under field conditions.
Overloaded and overwhelmed: Weakened partner aspirations of women public accountants during the COVID‐19 pandemic
Authors: Barnes Beau Grant , Cussatt Marc , Dalton Derek W. , Harp Nancy L. 
Published: September 2024

AbstractDespite years of initiatives to improve gender equity in public accounting firms, women continue to be underrepresented at the partner level. Supporting women's aspirations to become partner is important to ensure there are more women in the pipeline of potential partners. However, we argue that challenges during the COVID‐19 pandemic are likely to have negative downstream effects on accounting firms' efforts to improve female partner representation. Therefore, using a survey of 192 certified public accountants (CPAs), we develop and test a theoretical model that examines changes in women's partner aspirations during the COVID‐19 pandemic. Using the conservation of resources (COR) theory, we predict that women experienced disproportionately higher role overload during the pandemic compared to men. We also rely upon COR theory to predict that higher levels of role overload will be associated with weakened partner‐track motivations (i.e., less value placed on the advantages of the partner level and lower willingness to make the sacrifices necessary to pursue the partner level) and weakened partner aspirations. Consequently, we expect that women public accountants experienced weakened partner aspirations through higher role overload during the pandemic. Results support our predictions as we find that women experienced higher levels of role overload, which are associated with weakened partner‐track motivations, which in turn are associated with weakened partner aspirations. In sum, our results suggest that the COVID‐19 pandemic exacerbated pre‐pandemic gender equity challenges within public accounting firms. Fortunately, we also find that higher levels of supervisor support and coworker support help limit role overload and mitigate declines in partner aspirations. We discuss several insights that firms can use to mitigate post‐pandemic declines in women's partner aspirations.
Proteomic analysis across aged tissues reveals distinct signatures and the crucial involvement of midgut barrier function in the regulation of aging
Authors: Zhang Congying , Wang Jinlong , Yao Tianzhao , Hu Jiaxin , Sun Feifei , Feng Chunlu , Sun Zhendong , Shao Yuzhuo , Wang Zhu , Wu Jiarui , Huang Yunpeng 
Published: September 2024

AbstractThe process of aging is a natural phenomenon characterized by gradual deterioration in biological functions and systemic homeostasis, which can be modulated by both genetic and environmental factors. Numerous investigations conducted on model organisms, including nematodes, flies, and mice, have elucidated several pivotal aging pathways, such as insulin signaling and AMPK signaling. However, it remains uncertain whether the regulation of the aging process is uniform or diverse across different tissues and whether manipulating the same aging factor can result in consistent outcomes in various tissues. In this study, we utilize the Drosophila organism to investigate tissue‐specific proteome signatures during the aging process. Although distinct proteins undergo changes in aged tissues, certain common altered functional networks are constituently identified across different tissues, including the decline of the mitochondrial ribosomal network, autophagic network, and anti‐ROS defense networks. Furthermore, downregulation of insulin receptor (InR) in the midguts, muscle, and central nervous system (CNS) of flies leads to a significant extension in fly lifespans. Notably, despite manipulating the same aging gene InR, diverse alterations in proteins are observed across different tissues. Importantly, knockdown of InR in the midguts leads to a distinct proteome compared with other tissues, resulting in enhanced actin nucleation and glutathione metabolism, while attenuating age‐related elevation of serine proteases. Consequently, knockdown of InR results in rejuvenation of the integrity of the midgut barrier and augmentation of anti‐ROS defense capabilities. Our findings suggest that the barrier function of the midgut plays a pivotal role in defending against aging, underscoring the paramount importance of maintaining optimal gut physiology to effectively delay the aging process. Moreover, when considering age‐related changes across various tissues, it is more reasonable to identify functional networks rather than focusing solely on individual proteins.
Pain and unhealthy alcohol use among people living with HIV: A prospective cohort study
Authors: Palfai Tibor P. , Winter Michael R. , Magane Kara M. , Heeren Timothy C. , Bernier Lauren B. , Murray Grace E. , Saitz Richard , Kim Theresa W. , Stein Michael D. 
Published: September 2024

AbstractBackgroundUnhealthy alcohol use is prevalent among people living with HIV/AIDS (PLWH) and contributes to impaired functioning, diminished quality of life, and poorer HIV outcomes. Common cooccurring conditions such as chronic pain may be associated with negative outcomes both directly and through its influence on unhealthy drinking itself. However, there is relatively little known about how pain influences unhealthy drinking among PLWH over time. The current study examined whether pain was associated with indices of unhealthy alcohol use, namely heavy drinking and alcohol use disorder (AUD) assessed 12 months later.MethodsThe study sample (n = 207) was from the Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort, a prospective cohort of PLWH with a history of illicit substance or unhealthy alcohol use. We conducted logistic regression analyses to examine the associations between pain and both heavy drinking and AUD status (DSM‐5 criteria) (yes/no) over time. In secondary analyses, we examined whether pain was associated with greater AUD severity and whether pain interference was associated with heavy drinking and AUD outcomes.ResultsWe found that pain at baseline was associated with greater odds of AUD [aOR = 2.29 (95% CI: 1.13, 4.64), p = 0.02] but not heavy drinking [aOR = 0.91 (95% CI: 0.44, 1.88), p = 0.79] at 12 months. Pain was also associated with more severe AUD. Analyses of pain interference showed similar results.ConclusionsPain is prospectively associated with higher odds of AUD among PLWH with a substance/unhealthy alcohol use history. Providers should routinely address pain among PLWH to improve AUD outcomes.
High post‐sex survival of the world's largest semelparous mammal
Authors: Cowan Mitchell A. , Dunlop Judy A. , Hernandez‐Santin Lorna , Heidrich Astrid , Knuckey Chris G. , Nimmo Dale G. 
Published: September 2024

AbstractMales of the endangered northern quoll (Dasyurus hallucatus) are facultatively semelparous, often dying following their first breeding season. This is often driven by high breeding costs: males travel and mate extensively in breeding season, resulting in reduced body condition. Annual post‐breeding survival rates for male northern quolls have been recorded between 0% and 12.5% across their range in northern Australia. We highlight an observed 50% survival rate of male northern quolls (3 of 6) living into their second year in a Pilbara mining landscape. High male survival here may be attributed to above average rainfall in the landscape and reduced breeding opportunities, due to low female abundance—likely driven by large amounts of unfavourable mining land. This likely led to lower hormonal stress associated with breeding for males, as well as increased resource availability. Given northern quoll population persistence is highly dependent on breeding success, high survival of male northern quolls may inadvertently stabilize populations if they can breed again in a second year, though this is yet to be observed in the Pilbara region. Nevertheless, semelparity of male northern quolls likely varies with environmental and demographic factors, demonstrating that northern quoll populations may be resilient to disturbance in an unpredictable semi‐arid environment.
Importance of Heritage Structures as Bat Roosts in the Sahara Desert
Authors: Węgiel Andrzej , Fushiya Tomomi , Obłuski Artur , Tryjanowski Piotr 
Published: September 2024

ABSTRACTIn addition to the availability of water and invertebrate prey, roost sites are considered the main factors enabling bats to survive in desert areas. Because suitable roost sites are often limiting resources, human constructions are also important for these animals. Conversely, in the context of built heritage conservation, bats are often discussed as a cause of damages. However, if historic structures deteriorate, they may lose their suitability as roosting sites for bats. This study examines how the condition of domed tombs in Sudan affects their use by bats. Inspections of 19 tombs revealed that bats occupied only undamaged structures, with 1652 individuals of four species found. Slightly and partially damaged tombs were not used by bats. These findings highlight the importance of preserving man‐made structures as critical roosting sites in arid environments to support local bat populations.