bluuebunny/crossref_metadata_2025_split huggingface dataset:
Writing ‘between-the-six’: Mentorship, distance and the co-construction of dissertation research
Authors: Kee Jessica Célèste , Lomeli Hilario , Thatte Asavari , Thompson Christine Marmé , Powell Kimberly A. , Carpenter, II B. Stephen 
Published: March 2017

Abstract
In this article, three faculty members and three doctoral students make visible the mutual construction of dissertation research. Through a collaborative and duographic approach, the co-authors write in pairs to explore the relational, affective, and personal processes surrounding mentoring doctoral research. The pairs of duographic narratives are placed side by side to enable multifaceted interaction ‘between-the-six’ authors. The authors theorize and perform the process and concept of mentoring through affective, embodied, sensory, reflective, and dialogic encounters. They also acknowledge the ways in which all mentoring encounters differ and are therefore subject to how individual awarenesses inform multiple, collective, and reciprocal understandings.
Novos movimentos sociais e extensão universitária: para uma configuração democrática de saberes
Authors: Cortizo Maria Del Carmen 
Published: March 2017

Este artigo apresenta algumas reflexões acerca das relações entre os novos movimentos sociais e a universidade através da extensão, salientando as possibilidades que este tipo de atividade traz para uma construção democrática de saberes. Desenvolvemos as nossas análises em três momentos: em primeiro lugar caracterizamos alguns aspectos da atual crise da universidade. Em segundo lugar situamos teoricamente o protagonismo dos novos movimentos sociais desde uma perspectiva não determinista partindo do pressuposto de que as relações sociais estão marcadas hoje pela pluralidade de grupos e identidades não homogeneizáveis, com linguagens, saberes, agendas, características e demandas próprias. Finalmente, tratamos possibilidades abertas pela extensãona direção da superação da crise da universidade no diálogo com questões e saberes colocados em pauta pelos novos movimentos sociais.
Formação em Comunicação Social, currículo e práticas de extensão universitária
Authors: Henriques Márcio Simeone 
Published: March 2017

O artigo discute o papel das práticas extensionistas para a formação em Comunicação Social no Brasil, diante das intensas trans formações nas formas contemporâneas de comunicação e na prática deste campo profissional, bemcomo do contexto de implantação de novas diretrizes curriculares nacionais para os cursos da área. Partindo da ideia de uma relação intrínseca entre extensão e comunicação, destaca uma posição privilegiada que a prática comunicacionalocupa na produção e efetividade das ações de extensão e, em sentido inverso, as possibilidades e limites para uma visão mais integrada e orgânica da extensão aos projetos pedagógicos.
Desafíos en el diseño e implementación del Programa Integral de la Cuenca del Arroyo San Antonio de la Universidad de la República
Authors: Piedracueva Maximiliano , Benelli Leticia , Holly Lucía , Bandera Victoria 
Published: March 2017

En el año 2015, el Centro Universitario Salto de la Universidad de la República (UdelaR) comienza el diseño del Programa Integral de la Cuenca del Arroyo San Antonio (PICASA). Dicho programa surge como política institucional de extensiónuniversitaria con el objetivo de coordinar y articular las actividades de enseñanza, extensión e investigación que se realizan en dicho espacio. El presente artículo da cuenta del proceso de diseño e implementación del PICASA en un contextouniversitario particular dadas las características del Centro Universitario y las transformaciones políticas e institucionales de la extensión universitaria en UdelaR. Reflexiona sobre este dispositivo institucional denominado Programa Integral y sobre los desafíos metodológicos, conceptuales, institucionales y degestión que se presentan en su implementación.
La dimensión educativa y solidaria del voluntariado en la Universidad Nacional del Litoral
Authors: Blesio Marcel Mónica , Mendoza Marcelo 
Published: March 2017

La intención de promover la participación de toda la comunidad universitaria, fundamentalmente de estudiantes de nuestra universidad en dispositivos institucionales existentes, plantea desafíos importantes para la gestión académica.La decisión de ampliar y enriquecer el concepto de prácticas voluntarias y solidarias, incorporando la dimensión educativa y pedagógica que ellas encierran, ha marcado diferencias con concepciones más tradicionales del voluntariado quetambién tienen vigencia.Este artículo se propone recuperar la experiencia de más de una década del Programa del Voluntariado en la Universidad Nacional del Litoral, así como hacer explícitos los fundamentos de su creación, el andamiaje normativo, las perspectivasteóricas donde se sustenta y los dispositivos de gestión desarrollados para llevar adelante esta política universitaria.
FINANCIAL CAPABILITY STUDY OF MICRO, SMALL AND MEDIUM ENTERPRISES OWNER WITH SUPERIOR PRODUCT IN MADIUN REGENCY
Authors: Suryani Tatik 
Published: March 2017

Financial Capability is become the main topic in this study. The firts aim of this study is to analyze and measure financial capability of MSME (Micro, Small and Medium Enterprises) owner with superior products. The subjects of this study are MSME owner in Madiun Regency, East Java, Indonesia. Financial Capabilty measure by Funding Decision, Proft Sharing, Investment Decision and Financial Performance. By using triangulation method, this study found that Fincancial Capability of the MSME owner still on low level. MSME's funding decision is limited and not supported by third party like Bank. MSME's profit sharing is good for MSME's development. But their perception about business development is not right. MSME's Investment decision perception about land investment is wrong.
Coding of spatial attention priorities and object features in the macaque lateral intraparietal cortex
Authors: Levichkina Ekaterina , Saalmann Yuri B. , Vidyasagar Trichur R. 
Published: March 2017

AbstractPrimate posterior parietal cortex (PPC) is known to be involved in controlling spatial attention. Neurons in one part of the PPC, the lateral intraparietal area (LIP), show enhanced responses to objects at attended locations. Although many are selective for object features, such as the orientation of a visual stimulus, it is not clear how LIP circuits integrate feature‐selective information when providing attentional feedback about behaviorally relevant locations to the visual cortex. We studied the relationship between object feature and spatial attention properties of LIP cells in two macaques by measuring the cells' orientation selectivity and the degree of attentional enhancement while performing a delayed match‐to‐sample task. Monkeys had to match both the location and orientation of two visual gratings presented separately in time. We found a wide range in orientation selectivity and degree of attentional enhancement among LIP neurons. However, cells with significant attentional enhancement had much less orientation selectivity in their response than cells which showed no significant modulation by attention. Additionally, orientation‐selective cells showed working memory activity for their preferred orientation, whereas cells showing attentional enhancement also synchronized with local neuronal activity. These results are consistent with models of selective attention incorporating two stages, where an initial feature‐selective process guides a second stage of focal spatial attention. We suggest that LIP contributes to both stages, where the first stage involves orientation‐selective LIP cells that support working memory of the relevant feature, and the second stage involves attention‐enhanced LIP cells that synchronize to provide feedback on spatial priorities.
Inhibition of MAPK‐Erk pathway in vivo attenuates aortic valve disease processes in Emilin1‐deficient mouse model
Authors: Munjal Charu , Jegga Anil G. , Opoka Amy M. , Stoilov Ivan , Norris Russell A. , Thomas Craig J. , Smith J. Michael , Mecham Robert P. , Bressan Giorgio M. , Hinton Robert B. 
Published: March 2017

AbstractAortic valve disease (AVD) is a common condition with a progressive natural history, and presently, there are no pharmacologic treatment strategies. Elastic fiber fragmentation (EFF) is a hallmark of AVD, and increasing evidence implicates developmental elastic fiber assembly defects. Emilin1 is a glycoprotein necessary for elastic fiber assembly that is present in both developing and mature human and mouse aortic valves. The Emilin1‐deficient mouse (Emilin1−/−) is a model of latent AVD, characterized by activated TGFβ/MEK/p‐Erk signaling and upregulated elastase activity. Emilin1−/− aortic valves demonstrate early EFF and aberrant angiogenesis followed by late neovascularization and fibrosis. The objective of this study was to test the effectiveness of three different targeted therapies. Aged (12–14 months) Emilin1−/− mice were treated with refametinib (RDEA‐119, MEK1/2 inhibitor), doxycycline (elastase inhibitor), or G6‐31 (anti‐VEGF‐A mouse antibody) for 4 weeks. Refametinib‐ and doxycycline‐treated Emilin1−/− mice markedly reduced MEK/p‐Erk activation in valve tissue. Furthermore, both refametinib and doxycycline attenuated elastolytic cathepsin K, L, MMP‐2, and MMP‐9 activation, and abrogated macrophage and neutrophil infiltration in Emilin1−/− aortic valves. RNAseq analysis was performed in aortic valve tissue from adult (4 months) and aged (14 months) Emilin1−/− and age‐matched wild‐type control mice, and demonstrated upregulation of genes associated with MAPK/MEK/p‐Erk signaling and elastases at the adult stage and inflammatory pathways at the aged stage controlling for age. These results suggest that Erk1/2 signaling is an important modulator of early elastase activation, and pharmacological inhibition using refametinib may be a promising treatment to halt AVD progression
Decreased transcriptional corepressor p107 is associated with exercise‐induced mitochondrial biogenesis in human skeletal muscle
Authors: Bhattacharya Debasmita , Ydfors Mia , Hughes Meghan C. , Norrbom Jessica , Perry Christopher G. R. , Scimè Anthony 
Published: March 2017

AbstractIncreased mitochondrial content is a hallmark of exercise‐induced skeletal muscle remodeling. For this process, considerable evidence underscores the involvement of transcriptional coactivators in mediating mitochondrial biogenesis. However, our knowledge regarding the role of transcriptional corepressors is lacking. In this study, we assessed the association of the transcriptional corepressor Rb family proteins, Rb and p107, with endurance exercise‐induced mitochondrial adaptation in human skeletal muscle. We showed that p107, but not Rb, protein levels decrease by 3 weeks of high‐intensity interval training. This is associated with significant inverse association between p107 and exercise‐induced improved mitochondrial oxidative phosphorylation. Indeed, p107 showed significant reciprocal correlations with the protein contents of representative markers of mitochondrial electron transport chain complexes. These findings in human skeletal muscle suggest that attenuated transcriptional repression through p107 may be a novel mechanism by which exercise stimulates mitochondrial biogenesis following exercise.
Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension‐related sympathoexcitation
Authors: Marins Fernanda R. , Iddings Jennifer A. , Fontes Marco A. P. , Filosa Jessica A. 
Published: March 2017

AbstractThe intermediate region of the posterior insular cortex (intermediate IC) mediates sympathoexcitatory responses to the heart and kidneys. Previous studies support hypertension‐evoked changes to the structure and function of neurons, blood vessels, astrocytes and microglia, disrupting the organization of the neurovascular unit (NVU). In this study, we evaluated the functional and anatomical integrity of the NVU at the intermediate IC in the spontaneously hypertensive rat (SHR) and its control the Wistar‐Kyoto (WKY). Under urethane anesthesia, NMDA microinjection (0.2 mmol/L/100 nL) was performed at the intermediate IC with simultaneous recording of renal sympathetic nerve activity (RSNA), heart rate (HR) and mean arterial pressure (MAP). Alterations in NVU structure were investigated by immunofluorescence for NMDA receptors (NR1), blood vessels (70 kDa FITC‐dextran), astrocytes (GFAP), and microglia (Iba1). Injections of NMDA into intermediate IC of SHR evoked higher amplitude responses of RSNA, MAP, and HR. On the other hand, NMDA receptor blockade decreased baseline RSNA, MAP and HR in SHR, with no changes in WKY. Immunofluorescence data from SHR intermediate IC showed increased NMDA receptor density, contributing to the SHR enhanced sympathetic responses, and increased in vascular density (increased number of branches and endpoints, reduced average branch length), suggesting angiogenesis. Additionally, IC from SHR presented increased GFAP immunoreactivity and contact between astrocyte processes and blood vessels. In SHR, IC microglia skeleton analysis supports their activation (reduced number of branches, junctions, endpoints and process length), suggesting an inflammatory process in this region. These findings indicate that neurogenic hypertension in SHR is accompanied by marked alterations to the NVU within the IC and enhanced NMDA‐mediated sympathoexcitatory responses likely contributors of the maintenance of hypertension.
Interaction between plasma fetuin‐A and free fatty acids predicts changes in insulin sensitivity in response to long‐term exercise
Authors: Lee Sindre , Norheim Frode , Gulseth Hanne L. , Langleite Torgrim M. , Kolnes Kristoffer J. , Tangen Daniel S. , Stadheim Hans K. , Gilfillan Gregor D. , Holen Torgeir , Birkeland Kåre I. , Jensen Jørgen , Drevon Christian A. 
Published: March 2017

AbstractThe hepatokine fetuin‐A can together with free fatty acids (FFAs) enhance adipose tissue (AT) inflammation and insulin resistance via toll‐like receptor 4 (TLR4). Although some of the health benefits of exercise can be explained by altered release of myokines from the skeletal muscle, it is not well documented if some of the beneficial effects of exercise can be explained by altered secretion of hepatokines. The aim of this study was to examine the effect of interaction between fetuin‐A and FFAs on insulin sensitivity after physical exercise. In this study, 26 sedentary men who underwent 12 weeks of combined endurance and strength exercise were included. Insulin sensitivity was measured using euglycemic‐hyperinsulinemic clamp, and AT insulin resistance was indicated by the product of fasting plasma concentration of FFAs and insulin. Blood samples and biopsies from skeletal muscle and subcutaneous AT were collected. Several phenotypic markers were measured, and mRNA sequencing was performed on the biopsies. AT macrophages were analyzed based on mRNA markers. The intervention improved hepatic parameters, reduced plasma fetuin‐A concentration (~11%, P < 0.01), slightly changed FFAs concentration, and improved glucose infusion rate (GIR) (~33%, P < 0.01) across all participants. The change in circulating fetuin‐A and FFAs interacted to predict some of the change in GIR (β = −42.16, P = 0.030), AT insulin resistance (β = 0.579, P = 0.003), gene expression related to TLR‐signaling in AT and AT macrophage mRNA (β = 94.10, P = 0.034) after exercise. We observed no interaction effects between FFAs concentrations and leptin and adiponectin on insulin sensitivity, or any interaction effects between Fetuin‐A and FFAs concentrations on skeletal muscle TLR‐signaling. The relationship between FFAs levels and insulin sensitivity seemed to be specific for fetuin‐A and the AT. Some of the beneficial effects of exercise on insulin sensitivity may be explained by changes in circulating fetuin‐A and FFAs, promoting less TLR4 signaling in AT perhaps by modulating AT macrophages.
The Periodic Table (continued?): Eka-francium Et Seq.
Authors: Karol Paul J. 
Published: March 2017

AbstractIronically, the IUPAC Gold Book includes no definition of the “Periodic Table”. Nevertheless, Chemistry International’s readership assuredly knows what the Periodic Table is, or at least, what it has been, since that perception might change in the future. If the conversation is to be about prospects beyond the element with atomic number
Two Faces of Self-determination in Political Divorce
Authors: Liu Han 
Published: March 2017

Abstract
For decades, international law has denied the right to secede even if it enshrines self-determination. Existing scholarship explains this contradiction by opposing the right to self-determination and the principle of territorial integrity: self-determination itself does not justify a valid claim to the disputed territory. This article, against conventional wisdom, argues that the opposition is superficial. The real problem lies within the notion of self-determination itself. Self-determination contains within it two opposite faces: one breeds separatist movements; the other supports unification and territorial sovereignty. Historically, self-determination grounded both union and separation in the rise of the nation-state; secessionist self-determination only came into play when epochal wars had weakened the sovereignty of the parent state. Conceptually, the ambiguity of self-determination makes defining the ‘self’ a daunting task for the law, especially when both the parent state and the seceding group make national claims.
Saccadic Suppression Is Embedded Within Extended Oscillatory Modulation of Sensitivity
Authors: Benedetto Alessandro , Morrone Maria Concetta 
Published: March 2017

Action and perception are intimately coupled systems. One clear case is saccadic suppression, the reduced visibility around the time of saccades, which is important in mediating visual stability; another is the oscillatory modulation of visibility synchronized with hand action. To suppress effectively the spurious retinal motion generated by the eye movements, it is crucial that saccadic suppression and saccadic onset be temporally synchronous. However, the mechanisms that determine this temporal synchrony are unknown. We investigated the effect of saccades on contrast discrimination sensitivity over a long period stretching over >1 s before and after saccade execution. Human subjects made horizontal saccades at will to two stationary saccadic targets separated by 20°. At a random interval, a brief Gabor patch was displayed between the two fixations in either the upper or lower visual field and the subject had to detect its location. Strong saccadic suppression was measured between −50 and 50 ms from saccadic onset. However, the suppression was systematically embedded in a trough of oscillations of contrast sensitivity that fluctuated rhythmically in the delta range (at ∼3 Hz), commencing ∼1 s before saccade execution and lasting for up to 1 s after the saccade. The results show that saccadic preparation and visual sensitivity oscillations are coupled and the coupling might be instrumental in temporally aligning the initiation of the saccade with the visual suppression.SIGNIFICANCE STATEMENTSaccades are known to produce a suppression of contrast sensitivity at saccadic onset and an enhancement after saccadic offset. Here, we show that these dynamics are systematically embedded in visual oscillations of contrast sensitivity that fluctuate rhythmically in the delta range (at ∼3 Hz), commencing ∼1 s before saccade execution and lasting for up to 1 s after the saccade. The results show that saccadic preparation and visual sensitivity oscillations are coupled and the coupling might be instrumental in aligning temporally the initiation of the saccade with the visual suppression.
Systematic Importance of Pollen Morphology of Some Plants of (Lamiaceae)
Authors: M.F Azzazy, 
Published: March 2017

<p>Pollen morphology of seven taxa belonging to Lamiaceae and common used as medicinal plants were examined by light (LM) and scanning electron microscopy (SEM).<em> Thymus vulgaris</em> L.<em>, Mentha longifolia</em> (<a title="Carolus Linnaeus" href="https://en.wikipedia.org/wiki/Carolus_Linnaeus">L.</a>) <a title="William Hudson (botanist)" href="https://en.wikipedia.org/wiki/William_Hudson_(botanist)">Huds.</a> Mentha<em> spicata L.</em>, <em>Ocimum basillicium L.</em>, <em>Salvia elegans </em>Vahl<em>, Salvia farinace</em><em>a</em> Benth, and<em> Salvia splendens</em> Sellow ex Roem. and Schult. Pollen morphological characteristics are provided for these taxa. Among the studied taxa, <em>Mentha longifolia</em> has the smallest pollen grains, and <em>Ocimum basillicium</em> possesses the largest ones. The main shape of pollen grains in the most taxa suboblate, oblate – spheroidal or prolate–spheroidal. However subprolate are recorded for <em>Salvia elegans</em>. The grains are hexacolpate in all taxa, but in <em>S.</em><strong><em> </em></strong><em>farinacea</em> octacolpate pollen was found. Three distinct exine sculpturing exist, reticulate–perforate the common type, also reticulate, granulate and bi-reticulate. However, the fine details are characteristic to differentiate between the pollen species. Exine is microreticulate in case of <em>S</em>. <em>elegans</em> and <em>S.</em><strong><em> </em></strong><em>farinacea</em>, but reticulate-foveolate in case of S<em>. splendens</em>. As well as, the presence of holes on colpus membrane ornamentation can be used as a taxonomic tool for sectional division between. <em>S. </em><em>elegans</em> from <em>S</em><em>. splendens</em> is clearly distinct from the other taxa examined by its characteristic pollen morphology. </p>
Morphological studies and development of Ex-situ protocol for rehabilitation of threatened Rheum species under nursery conditions
Authors: Tabin Shagoon , Kamili Azra.N. , Gupta R.C. 
Published: March 2017

<p><em>Rheum</em> is a strong vigorous plant and can live long even in tough conditions. The <em>Rheum</em> species have been domesticated as medicinal plants for human consumption. <em>Rheum</em> species are perennial stout herbs. Rhubarb is a common English name of the genus <em>Rheum</em>. Rhubarb is a plant name for the many different species of <em>Rheum</em>, distributed in the temperate and sub tropical regions of Himalaya from Kashmir to Sikkim and growing wild in the mountains of the Western and North-western provinces of China and adjoining Tibetan territory. It is cultivated much in Europe and the United States. In Kashmir Himalaya, it ranges from an altitude of 1700 - 5500m. It is famous for its medicinal uses. Roots are long and stout. Stem is erect, hollow, sulcate, glabrous or strigose. It is native to Asia-Temperate to Asia – Tropical, from China to India, Nepal and Pakistan. In India, its found in Himachal Pradesh Jammu &amp; Kashmir and Uttar Pradesh. In Jammu and Kashmir, it grows on open slopes and shrubberies in Kashmir, Leh and Zanaskar valley between 3000-5000 m, where <em>R.webbianum</em> is found. The <em>Rheum spiciforme</em> is also one of most known medicinal plant and is found on high altitudes of Gurez valley(3000m 5000m). <em>Rheum</em> also prefers a full sunny location and thrives in a moist, fertile soil. Most <em>Rheum</em> species can handle heavier clay soils better than many other herbs and makes a striking addition to the spring landscape. Rhubarb is propagated from seeds, seedlings, or pieces of rhizome. </p>