bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social media usage and sustainable performance in manufacturing supply chains: exploring dynamic capabilities
Authors: Basit Abdul , Javed Asma , Ejaz Sarmad , Nasir Aemin , Ridwan Abdur-Rahman , Ahmed Sana 
Published: September 2024

AbstractDue to the global impact of COVID-19, businesses and supply chains worldwide have been disrupted, leading to challenges for manufacturing firms and customers. Social media usage (SMU) is a vital and valuable tool that builds customer-centric supply chains by effectively communicating large volumes of valuable data. This study examines the influence of social media usage on the development of dynamic capabilities, including supply chain sensing capabilities (SCSC), knowledge sharing capability (KSC), and social capital (SC), which are crucial for constructing agile and resilient supply chains that can effectively respond to dynamic and turbulent environments, ultimately enhancing sustainable business performance. To assess the proposed investigation model, data was gathered through a structured questionnaire administered to supply chain members currently engaged with manufacturing firms. The evaluation of the proposed hypotheses is carried out through the application of structural equation modeling (SEM). The results of this study offer empirical evidence supporting the proposition that SMU within manufacturing firms promotes the development of sensing capabilities, knowledge-sharing capability, and social capital. Furthermore, this study tests the moderation role of environmental dynamism in the relationship between social media use and sustainable business performance. This underscores the pivotal role played by SMU in facilitating the adaptation and responsiveness of the supply chain to dynamic and uncertain environments, thereby contributing to the long-term sustainability and competitiveness of organizations.
Updated data and characterization factors of the criticality assessment for the integrated method to assess resource efficiency (ESSENZ and ESSENZ+)
Authors: Bach Vanessa , Marinova Sylvia , Finkbeiner Matthias 
Published: September 2024

Abstract
Objectives
This data note contains updated characterization factors including the corresponding datasets for the integrated method to assess resource efficiency (abbreviated as ESSENZ) as well as its successor (ESSENZ+) utilized in assessing the criticality of 48 abiotic resources. The updated characterization factors enable life cycle-based case studies of product systems to determine criticality aspects as well as aspects related to compliance with social and environmental impacts. Underlying data is provided as it is needed for efficiently interpreting the results.

Data description
Data was collected from publicly available source, including i.e. the United States Geological Survey for abiotic resource production and reserves, the Fraser Institute for the Policy Perception Index, the World Economic Forum for the Enabling Trade Index, the World Bank for the Worldwide Governance Indicators and the German Mineral Resources Agency for price fluctuations. The compiled data has been reorganized and recalculated in accordance with the principles outlined in the published ESSENZ and ESSENZ + method, serving as a foundation for the calculation of the characterization factors for assessing criticality and compliance with social and environmental impacts.
Enhanced geological and radioactive mapping of Gabal Abu Ashayir-Gabal El Bakriyah area, central Eastern Desert, Egypt, using remotely sensing data
Authors: Salem Ibrahim Abdel Nagy , Kamh Samir Zaky , Saleh Gehad Mohamed , Abdel Ghani Ismail Mohamed , Badr Yasser Salah , Elsaid Mahmoud , Sayed Sabreen Amr 
Published: September 2024

AbstractThe primary goal of this work is to integrate airborne gamma-ray spectrometry with multispectral data from ASTER and Landsat-8 for mapping of the geology, radiometric data, and types of alterations of Gabal Abu Ashayir-Gabal El Bakriyah area, central Eastern Desert, Egypt. Utilizing various image processing techniques like color band composites (CBC), principal component analysis (PCA), band ratios (BR), and minimum noise fraction (MNF), it is possible to map the hydrothermal alterations zones and identify the lithological units under investigation. By identifying the various lithological units and alteration types, these results are validated and verified in the field. These methods’ outputs are combined to create an accurate geological map of the research region and tracing the propylitic, phyllic and iron oxy-hydroxides alterations. These rock units are ophiolitic mélange (oldest), arc metavolcanics, arc granitoids, younger gabbro, late-collision granites (monzogranites, syenogranites and alkali feldspar granites) and Nubian Sandstone (Taref formation and Quseir Formation) youngest, Furthermore, the radioactive anomalies are primarily associated with ferrugination zones (iron oxy-hydroxides alteration) at Gabal El Bakriyah monzogranite and alkali feldspar granite. The radioactive minerals are uranothorite, thorite and fergusonite. The opaque minerals that encountered at the rock units of Gabal Abu Ashayir-Gabal El Bakriyah are chromite, ilmenite, magnetite, chalcopyrite and chalcocite, whereas the non-opaque minerals comprises titanite, rutile, fluorite, garnet, zircon, apatite and barite.
How does Neoseiulus californicus McGregor respond to sublethal doses of entomopathogenic fungus Beauveria bassiana (Hyp.: Cordycipitaceae)?
Authors: Kheradmand Katayoon , Heidari Mahmoud , Sedaratian-Jahromi Amin , Talaei-Hassanloui Reza , Havasi Mohammadreza 
Published: September 2024

AbstractTwo-spotted spider mite, Tetranychus urticae Koch (Acari: Prostigmata), is one of the most economically important mite species, mainly controlled by chemical acaricides. Natural enemies have been assessed as reliable alternatives for management of this phytophagous mite. In the current project, demographic characteristics of Neoseiulus californicus McGregor (Acari: Phytoseiidae) to sublethal concentrations (LC10 = 6.76 × 102, LC20 = 8.74 × 103 and LC30 = 55.38 × 103 conidia ml−1) of entomopathogenic fungus, Beauveria bassiana (Bals.) Vuill. TV strain were investigated under laboratory conditions at 25 ± 2°C, 70 ± 5% RH and a photoperiod of 16:8 (L:D) h. Our results indicated that when adult predators were exposed to LC20 and LC30 of B. bassiana, the oviposition period was significantly reduced compared with other treatments. Neoseiulus californicus fecundity was significantly greater in the control (37 eggs) than in LC30 (24 eggs). Life table analysis revealed that the net reproductive rate (R0) declined as the sublethal concentrations of B. bassiana increased. The most striking result to emerge from the data is that not only intrinsic (r); but also, finite rate of increase (λ) was not significantly affected by different concentrations of B. bassiana. Our findings revealed some potential interactions of B. bassiana and N. californicus during their combinations for managing T. urticae that may be helpful for optimising control of this important pest.
Evaluation of diets from various maize hybrids reveals potential tolerance traits against Spodoptera littoralis (Boisd) as measured by developmental and digestive performance
Authors: Alekaram Shirin , Hemmati Seyed Ali , Ziaee Masumeh , Stelinski Lukasz L. 
Published: September 2024

AbstractSpodoptera littoralis (Boisd) (Lepidoptera: Noctuidae) is a highly polyphagous insect that significantly reduces agricultural production of several food staples. We evaluated performance of S. littoralis on several meridic diets based on various maize hybrids, including Oteel, Simon, Valbum, SC703, and SC704. Growth, feeding behaviours, and activity of digestive enzymes of S. littoralis were examined under laboratory conditions. In addition, selected biochemical characteristics of maize hybrid seeds were evaluated, including starch, protein, anthocyanin, as well as phenolic and flavonoid contents, to examine relationships between plant properties and digestive performance of S. littoralis. Performance of S. littoralis on maize hybrids, as measured by nutritional indices, was related to both proteolytic and amylolytic activities quantified using gut extracts. Larval S. littoralis reared on SC703 exhibited the highest efficiency of conversion of digested food, while the lowest was recorded in those fed on the Oteel hybrid. S. littoralis reared on SC703 and Oteel also exhibited the highest and lowest relative growth rates, respectively. The highest levels of proteolytic activity in S. littoralis were measured from larvae reared on the SC703 hybrid, while the lowest levels occurred on the Oteel and Valbum hybrids. Amylolytic activity was lowest in larvae reared on SC703 and Valbum hybrids and highest in larvae reared on the Oteel hybrid. Our results suggest that the SC703 hybrid was the most suitable host for S. littoralis, while the Oteel hybrid demonstrated the greatest level of tolerance against S. littoralis of those evaluated. We discuss the potential utility of maize hybrids exhibiting tolerance traits against this cosmopolitan pest with reference to cultivation of tolerant varieties and identification of specific tolerance traits.
“A season in hell”: The Rwandan genocide and the ICRC's Fundamental Principles
Authors: Cotter Cédric , Palmieri Daniel 
Published: September 2024

AbstractHow can humanitarians carry out their work during a genocide? Between April and June of 1994, the International Committee of the Red Cross (ICRC) faced that very question. After bloodshed broke out in Rwanda, the ICRC was the only remaining humanitarian organization in the country and continued its aid work while surrounded by brutal violence. Based on previously published materials,1 this article examines the strategies that enabled the ICRC to pursue its humanitarian mission in the face of the most basic inhumanity. In particular, the International Red Cross and Red Crescent Movement's Fundamental Principles of neutrality and impartiality were critical to establishing contact with all involved parties: dialogue, including with those perpetrating genocide, was key to ensuring the safety of ICRC staff, and to facilitating the organization's work on behalf of those affected by the violence. Additionally, the ICRC spoke out frequently as the violence was unfolding in Rwanda, and this article addresses the question of public communications, in both principle and practice, during a genocide.
Beyond the Wedge: Impact of Tidal Streams on Salinization of Groundwater in a Coastal Aquifer Stressed by Pumping and Sea‐Level Rise
Authors: Hingst M. C. , Housego R. M. , He C. , Minsley B. J. , Ball L. B. , Michael H. A. 
Published: September 2024

AbstractSaltwater intrusion (SWI) is a well‐studied phenomenon that threatens the freshwater supplies of coastal communities around the world. The development and advancement of numerical models has led to improved assessment of the risk of salinization. However, these studies often fail to include the impact of surface waters as potential sources of aquifer salinity and how they may impact SWI. Based on field‐collected data, we developed a regional, variable‐density groundwater model using SEAWAT for east Dover, Delaware. In this location, major users of groundwater from the surficial aquifer are the City of Dover and irrigation for agriculture. Our model includes salinized marshland and tidal streams, along with irrigation and municipal pumping wells. Model scenarios were run for 100 years and included changes in pumping rates and sea‐level rise (SLR). We examined how these drivers of SWI affect the extent and location of salinization in the surficial aquifer by evaluating differences in chloride concentration near surface waters and the subsurface freshwater‐saltwater interface. We found the presence of the marsh inverts the typical freshwater‐saltwater wedge interface and that the edge of the interface did not migrate farther inland. Additionally, we found that tidal streams are the dominant pathways of SWI at our site with salinization from streams being exacerbated by SLR. Our results also show that spatial distribution of pumping affects both the magnitude and extent of salinization, with an increase in concentrated pumping leading to more intensive salinization than a more widely distributed increase of the same total pumping volume.
Quantifying Post‐Colonial Peat Carbon Loss From a Drained Forested Peatland, Great Dismal Swamp National Wildlife Refuge, USA
Authors: Jones Miriam C. , Willard Debra A. , Wurster Frederic C. , Huber Molly 
Published: September 2024

AbstractPeatland carbon storage is increasingly threatened by the combination of land‐use change and climate variability, though carbon losses from land‐use changes that span centuries are difficult to quantify, particularly in systems where little undisturbed area remains. Here we use a combination of vegetation change, fire history, and calculations of excess ash mass to quantify carbon loss in the Great Dismal Swamp National Wildlife Refuge (GDS NWR), USA, a highly impacted oligotrophic temperate peat swamp. Our results indicate that ditch construction that began in the Colonial Era in the late 1700s and continued into the mid‐20th century across the swamp resulted in shifts from cypress‐tupelo swamps to a combination of maple‐gum and pine pocosin forests, consistent with drying surface conditions. Two large smoldering fires (2008, 2011) that were exacerbated by surface drainage, shifted vegetation from swamp to marsh, consumed peat over 25 km2, and caused losses of 1.05–1.34 Tg C due to peat burning. Across the Refuge as a whole, up to 48.2 Tg C has been lost to peat oxidation since ditch construction. Both stocks and rates of carbon loss remain higher than post‐disturbance accumulation across most of GDS NWR, suggesting that existing efforts to block drainages to elevate water tables may not be enough to offset carbon losses. Rewetting heavily impacted surface peats may reduce peat oxidation and carbon loss, and shift vegetation toward hydrologic conditions preferred by pre‐disturbance cypress‐tupelo swamps.
A piezoresistive-based 3-axial MEMS tactile sensor and integrated surgical forceps for gastrointestinal endoscopic minimally invasive surgery
Authors: Hou Cheng , Gao Huxin , Yang Xiaoxiao , Xue Guangming , Zuo Xiuli , Li Yanqing , Li Dongsheng , Lu Bo , Ren Hongliang , Liu Huicong , Sun Lining 
Published: September 2024

AbstractIn robotic-assisted surgery (RAS), traditional surgical instruments without sensing capability cannot perceive accurate operational forces during the task, and such drawbacks can be largely intensified when sophisticated tasks involving flexible and slender arms with small end-effectors, such as in gastrointestinal endoscopic surgery (GES). In this study, we propose a microelectromechanical system (MEMS) piezoresistive 3-axial tactile sensor for GES forceps, which can intuitively provide surgeons with online force feedback during robotic surgery. The MEMS fabrication process facilitates sensor chips with miniaturized dimensions. The fully encapsulated tactile sensors can be effortlessly integrated into miniature GES forceps, which feature a slender diameter of just 3.5 mm and undergo meticulous calibration procedures via the least squares method. Through experiments, the sensor’s ability to accurately measure directional forces up to 1.2 N in the Z axis was validated, demonstrating an average relative error of only 1.18% compared with the full-scale output. The results indicate that this tactile sensor can provide effective 3-axial force sensing during surgical operations, such as grasping and pulling, and in ex vivo testing with a porcine stomach. The compact size, high precision, and integrability of the sensor establish solid foundations for clinical application in the operating theater.
Creating a bacterium that forms eukaryotic nucleosome core particles
Authors: Jing Xinyun , Zhang Niubing , Zhou Xiaojuan , Chen Ping , Gong Jie , Zhang Kaixiang , Wu Xueting , Cai Wenjuan , Ye Bang-Ce , Hao Pei , Zhao Guo-ping , Yang Sheng , Li Xuan 
Published: September 2024

AbstractThe nucleosome is one of the hallmarks of eukaryotes, a dynamic platform that supports many critical functions in eukaryotic cells. Here, we engineer the in vivo assembly of the nucleosome core in the model bacterium Escherichia coli. We show that bacterial chromosome DNA and eukaryotic histones can assemble in vivo to form nucleosome complexes with many features resembling those found in eukaryotes. The formation of nucleosomes in E. coli was visualized with atomic force microscopy and using tripartite split green fluorescent protein. Under a condition that moderate histones expression was induced at 1 µM IPTG, the nucleosome-forming bacterium is viable and has sustained growth for at least 110 divisions in longer-term growth experiments. It exhibits stable nucleosome formation, a consistent transcriptome across passages, and reduced growth fitness under stress conditions. In particular, the nucleosome arrays in E. coli genic regions have profiles resembling those in eukaryotic cells. The observed compatibility between the eukaryotic nucleosome and the bacterial chromosome machinery may reflect a prerequisite for bacteria-archaea union, providing insight into eukaryogenesis and the origin of the nucleosome.
Molecular architecture of chitin and chitosan-dominated cell walls in zygomycetous fungal pathogens by solid-state NMR
Authors: Cheng Qinghui , Dickwella Widanage Malitha C. , Yarava Jayasubba Reddy , Ankur Ankur , Latgé Jean-Paul , Wang Ping , Wang Tuo 
Published: September 2024

AbstractZygomycetous fungal infections pose an emerging medical threat among individuals with compromised immunity and metabolic abnormalities. Our pathophysiological understanding of these infections, particularly the role of fungal cell walls in growth and immune response, remains limited. Here we conducted multidimensional solid-state NMR analysis to examine cell walls in five Mucorales species, including key mucormycosis causative agents like Rhizopus and Mucor species. We show that the rigid core of the cell wall primarily comprises highly polymorphic chitin and chitosan, with minimal quantities of β-glucans linked to a specific chitin subtype. Chitosan emerges as a pivotal molecule preserving hydration and dynamics. Some proteins are entrapped within this semi-crystalline chitin/chitosan layer, stabilized by the sidechains of hydrophobic amino acid residues, and situated distantly from β-glucans. The mobile domain contains galactan- and mannan-based polysaccharides, along with polymeric α-fucoses. Treatment with the chitin synthase inhibitor nikkomycin removes the β-glucan-chitin/chitosan complex, leaving the other chitin and chitosan allomorphs untouched while simultaneously thickening and rigidifying the cell wall. These findings shed light on the organization of Mucorales cell walls and emphasize the necessity for a deeper understanding of the diverse families of chitin synthases and deacetylases as potential targets for novel antifungal therapies.
The impact of lenvatinib on sarcopenia in patients with advanced unresectable hepatocellular carcinoma
Authors: Praktiknjo Michael , Pena Solano Ana S. , Sadeghlar Farsaneh , Welchowski Thomas , Schmid Matthias , Möhring Christian , Zhou Taotao , Mahn Robert , Monin Malte B. , Meyer Carsten , Feldmann Georg , Brossart Peter , van Beekum Cornelius , Semaan Alexander , Matthaei Hanno , Manekeller Steffen , Sprinkart Alois M. , Nowak Sebastian , Luetkens Julian , Kalff Jörg C. , Strassburg Christian P. , González-Carmona Maria A. 
Published: September 2024

AbstractLenvatinib is a multiple receptor tyrosine kinase inhibitor (TKI) approved for first-line treatment of patients with unresectable hepatocellular carcinoma (HCC). TKI are suspected of exacerbating muscle loss in patients with cancer. In this study, we analyze the role of muscle loss in patients with advanced HCC treated with lenvatinib. This is a retrospective analysis of a real-life cohort of 25 patients with advanced HCC who were treated with lenvatinib from 2018 to March 2021 in Germany. Patients were stratified for loss of skeletal muscle area during the first three months of lenvatinib therapy. Overall survival (OS), progression-free survival (PFS) and toxicity were analyzed for all patients, especially regarding loss of muscle before and during the first three months of therapy with lenvatinib. Three months after beginning of therapy with lenvatinib, a significant reduction of muscle mass was observed in 60% of patients (p = 0.035). Despite increase of loss of skeletal muscle, patients benefitted from lenvatinib in our cohort of patients in terms of OS and PFS and did not experience increased toxicity. Furthermore, muscle loss was not a negative predictor of survival in the univariate analysis (p = 0.675). Patients with advanced hepatocellular carcinoma experience muscle loss with lenvatinib therapy. However, despite progressive muscle loss, patients benefit from a therapy with lenvatinib in terms of OS and PFS without increased toxicity. However, assessment and prophylaxis of skeletal muscle status should be recommended during a therapy with lenvatinib.
The impact of the tumor microenvironment on the survival of penile cancer patients
Authors: Lohse Stefan , Mink Jan Niklas , Eckhart Lea , Hans Muriel Charlotte , Jusufi Leuart , Zwick Anabel , Mohr Tobias , Bley Isabelle Ariane , Khalmurzaev Oybek , Matveev Vsevolod Borisovich , Loertzer Philine , Pryalukhin Alexey , Hartmann Arndt , Geppert Carol-Immanuel , Loertzer Hagen , Wunderlich Heiko , Lenhof Hans-Peter , Naumann Carsten Maik , Kalthoff Holger , Junker Kerstin 
Published: September 2024

AbstractPeCa is a rare entity with rising incidence rates due to increased infections with human papillomaviruses (HPV). The distinct subtypes of PeCa with an individual pathogenesis demand biomarkers for a precise patient risk assessment regarding disease progression and therapeutic susceptibility. We recently identified promising candidates associated with an HPV-instructed tumor microenvironment (TME) using HPV-positive PeCa cell lines and tissue microarrays (TMA). The capacity of HPV + p63 + PeCa cells to release neutrophil-attracting CXCL-8 provided a molecular link explaining the infiltration of CD15 + myeloid cells in PeCa specimens. The candidate biomarkers HPV, p63, CD15, DKK1, and CD147 linked a tumor-promoting TME with a higher TNM classification reflecting more aggressive and metastasizing cancers. Based on immune-reactive scores (IRS) from TMA staining for these biomarkers, we calculated correlations and conducted association analyses to assess the degree of relationship between all biomarkers. We then conducted Kaplan–Meier survival estimates and Cox regression analyses to delineate the impact on PeCa patient survival. There is a notable predictive potential regarding the survival of patients with biomarker profiles beyond the potency of the individual biomarker. From all candidate biomarkers and biomarker profiles, the combination of CD147 and infiltrating CD15 + cells linked to an active HPV-driven transformation displayed cancer-immune dynamics with dismal prognosis for patients. After deciphering relevant interdependencies, the HPV + CD147 + CD15 + status was the most potent profile predicting metastasis-free survival of PeCa patients. The results of this report underscore the need for analysis of the TME and the development of multi-parameter composite scores that reflect fundamental cancer-immune relationships to tailor therapeutic interventions based on actual cancer immune dynamics.