bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying and controlling hazards to operating theatre personnel
Authors: Kerrigan Lynne 
Published: January 2016

Safety in the operating theatre for both staff and patients requires careful planning, use of appropriate personal protective equipment and demands daily attention by all members of the surgical team and support staff. This article aims to serve as a reminder of the potential hazards in the operating theatre and as a means of raising awareness of the potential risks. Working in an operating theatre is never going to be without risk, however if each member of theatre personnel develops the habit of focusing on both patient safety and occupational safety at the same time, risks and hazards may be minimised.
Comparative efficacy and safety of generic (Bergolak) vs. brand cabergoline in the treatment of patients with prolactin-secreting tumors
Authors: Melnichenko Galina Afanas'evna , Dzeranova Larisa Konstantinovna , Pigarova Ekaterina Aleksandrovna , Vorotnikova Svetlana Yur'evna 
Published: January 2016

Objective: To evaluate the effectiveness and safety of cabergoline drug Bergolak («Veropharm», Russia) in the treatment of patients with prolactin-secreting tumors.Materials and methods: The study included 14 patients (14 women, mean age 46±12) diagnosed with prolactinoma. The patients were switched to Bergolak after 1 month of treatment by original cabergoline. Dose of cabergoline varied from 0,125 mg to 3,25 mg per week. Prolactin level, symptoms of hyperprolactinemic hypogonadism, side-effects were evaluated at the baseline, after 1 month of original cabergoline treatment and 1 and 2 months of Bergolak therapy.Results: Statistical differences in the level of prolactin (p 0.05), and the incidence of side-effects (p 0.43) during Bergolak therapy in comparison with the original drug was not registered.Conclusions: Bergolak showed to be effective drug for treatment of patients with prolactin-secreting tumors. The incidence of side-effects during Bergolak therapy is equal to the original cabergoline treatment.
Hormonal status and the orexin system in obese patients with obstructive sleep apnea syndrome
Authors: Strueva Natalya Viktorovna , Melnichenko Galina Afanas'evna , Poluektov Mikhail Gur'evich , Savel'eva Larisa Viktorovna , Katsya Gulinara Viktorovna , Goncharov Nikolay Petrovich 
Published: January 2016

The aim of research was to estimate the influence of hormone metabolism and sleep apnea on patients with obesity. 76 patients (37 males and 39 females) with obesity were included in this study. After night polysomnography all patients were divided in two groups comparableby age, sex ratio and BMI. The first group consisted of 41 patients with obstructive sleep apnea syndrome (OSAS), the second (controls) – 35 patients without breath disorders during sleep. OSAS is accompanied by the increase in urinary cortisol during the night, high levels ofbasal insulin, disturbances of hepatic production of IGF-1, dysfunction of the pituitary-gonadal axis. Our results show that sleep-related breathing disorders render markedly and negatively affect on hormonal parameters of patients with obesity. As a reliable difference of basalsecretion of orexin A in obese patients with and without OSAS was not revealed (42,0 [14; 99,5] vs. 18,0 [14,5; 124,5] pg/ml; р=0,9), we were not able to show the existence that the existence of OSAS is followed by any special changes of activity of the orexin system.
Obesity and nonalcoholic fatty liver disease: metabolic risks and their correction
Authors: Komshilova Kseniya Andreevna , Troshina Ekaterina Anatol'evna 
Published: January 2016

Nonalcoholic fatty liver disease (NAFLD) – a common chronic disease of the liver, the main feature of which is the accumulation of fat in hepatocytes, is not related to alcohol abuse. NAFLD is associated with obesity, especially abdominal, metabolic syndrome and various metabolic markers of risk for cardiovascular disease and type 2 diabetes, which affects the incidence, prognosis and life expectancy of patients with obesity. This lecture describes the main causes of the disease, its pathogenesis, clinical presentation, diagnosis and treatment.
Down to the Nitty-Gritty: A case study of Collection Policies and Procedures in the Ethnology Department at the Sam Noble Oklahoma Museum of Natural History
Authors: Allen Stephanie L. 
Published: January 2016

Abstract
Although most museum professionals understand the differences between a Collection Management Policy (CMP) and collection procedures, many find it difficult to create, update, and implement these different documents. The creation of a procedural manual for the Ethnology Department at the Sam Noble Oklahoma Museum of Natural History (SNOMNH) at the University of Oklahoma and an update of SNOMNH’s CMP led to an examination of the differences between policies and procedures, the varying processes of creating and/or updating these different documents, the difficulties of policy/procedure implementation, and the ultimate necessity of both types of documents.
Communicating pesticide contamination messages
Authors: Henderson Jane , Rumsey Kloe 
Published: January 2016

Abstract
Over the last two decades, an increased understanding of the extent of pesticide contamination of organic collections in museums, particularly natural science and ethnographic collections, has developed. This paper explores the intellectual and emotional responses to messages about pesticide risks in museums and reports on the impact of wording on risk warnings. Six risk phrases using different terminology but intended to represent the same danger of pesticide contamination were evaluated by 103 museum staff. We found that how a message was delivered, the degree of science education of users, and phrases associated with hazards affected how a message was perceived. The delivery of risk warnings and the effective communication of collections-based hazards in museums are essential to responsible collections use, particularly those of scientific (Natural History) and cultural (Ethnographic) importance, where collections are most likely to be contaminated with hazardous substances. The results presented are a first step to understanding how the communication of pesticide risks in museums is understood by users of the collections. By understanding how a message is perceived, we provide advice to museum staff about language use for risk communication projects and management of behaviors.
Robust switched controller design for linear continuous-time systems
Authors: Ilka Adrian , Veselý Vojtech 
Published: January 2016

Abstract
In this paper we study a novel approach to the design of a robust switched controller for continuous-time systems described by a novel robust plant model using quadratic stability and multi parameter dependent quadratic stability approaches. In the proposed design procedure with an output feedback a novel quadratic cost function is proposed which allows to obtain different performance dependence on the working points. Finally a numerical examples are investigated.
Disturbance attenuation problem using a differential game approach for feedback linear quadratic descriptor systems
Authors: Musthofa Muhammad Wakhid 
Published: January 2016

Abstract
This paper studies the H∞ disturbance attenuation problem for index one descriptor systems using the theory of differential games. To solve this disturbance attenuation problem the problem is converted into a reduced ordinary zero-sum game. Within a linear quadratic setting the problem is solved for feedback information structure.
Reference trajectory tracking for a multi-DOF robot arm
Authors: Krasňanský Róbert , Valach Peter , Soós Dávid , Zarbakhsh Javad 
Published: January 2016

Abstract
This paper presents the problem of tracking the generated reference trajectory by the simulation model of a multi-DOF robot arm. The kinematic transformation between task space and joint configuration coordinates is nonlinear and configuration dependent. To obtain the solution of the forward kinematics problem, the homogeneous transformation matrix is used. A solution to the inverse kinematics is a vector of joint configuration coordinates calculated using of pseudoinverse Jacobian technique. These coordinates correspond to a set of task space coordinates. The algorithm is presented which uses iterative solution and is simplified by considering stepper motors in robot arm joints. The reference trajectory in Cartesian coordinate system is generated on-line by the signal generator previously developed in MS Excel. Dynamic Data Exchange communication protocol allows sharing data with Matlab-Simulink. These data represent the reference tracking trajectory of the end effector. Matlab-Simulink software is used to calculate the representative joint rotations. The proposed algorithm is demonstrated experimentally on the model of 7-DOF robot arm system.
Analysis Of The Method Of Predictive Control Applicable To Active Magnetic Suspension Systems Of Aircraft Engines
Authors: Kurnyta-Mazurek Paulina , Henzel Maciej , Kurnyta Artur 
Published: January 2016

AbstractConventional controllers are usually synthesized on the basis of already known parameters associated with the model developed for the object to be controlled. However, sometimes it proves extremely difficult or even infeasible to find out these parameters, in particular when they subject to changes during the exploitation lifetime. If so, much more sophisticated control methods have to be applied, e.g. the method of predictive control. Thus, the paper deals with application of the predictive control approach to follow-up tracking of an active magnetic suspension where the mathematical and simulation models for such a control system are disclosed with preliminary results from simulation investigations of the control system in question.
Rehabilitation of a Female Patient after Corrective Surgery for Tetralogy of Fallot
Authors: Cvetković Jovana , Đorđević Dragan Đ , Šljivić Milan , Ilić Marina Deljanin 
Published: January 2016

Summary
Herein we present a 25-year-old female patient with tetralogy of Fallot (TOF). This congenital heart defect is not very common, but it is the most common one among cyanotic heart defects. Treatment of the patients with TF is surgical, with palliative or curative (corrective) intent. Our patient underwent palliative surgery, definitive correction, and another surgery for pulmonary valve insufficiency. During cardiovascular rehabilitation, the patient was rhythmically stable, with excellent tolerance of physical exertion. Bearing in mind that this was a young female person who previously had had two spontaneous abortions, pregnancy was not absolutely contraindicated, although spontaneous abortion and pregnancy complications were more common in these patients.
Clinical significance of anti-C1q antibodies in SLE
Authors: Stiborová Ivana , Král Vlastimil , Rovenský Jozef , Blažíčková Stanislava 
Published: January 2016

Abstract
Lupus nephritis (LN) is a severe and frequent complication of systemic lupus erythematosus (SLE). Untreated cases very often lead to patients’ death; therefore, it is important to use markers sensitive and specific enough for the diagnosis and subsequent monitoring of nephritis. Autoantibodies against double-stranded DNA (anti-dsDNA) are believed to play a major role in SLE in general and so their significance in prediction and monitoring of glomerular inflammation is low. For prediction of renal flares and effective, well-timed therapy, it is required to have an appropriate marker available. In our study, we have tested sera of 85 SLE patients with or without LN. The criterion for LN determination was the degree of proteinuria (persistent proteinuria > 0.5 g/day, according to ACR criteria for LN). Disease activity was described by SLE disease index (SLEDAI) score, renal functions were stated according to British Isles Lupus Assessment Group score. There were anti-C1q, total anti-dsDNA and high-avidity anti-dsDNA detected in the patients’ sera. We did not find any significant difference in average SLEDAI value between patients with renal and non-renal organ complications. Positivity of anti-C1q was more frequent in patients with nephritis than in those without any history of renal disease (58.3 vs. 39.1%). Higher prevalence of these antibodies was evident in patients with clinically active LN than in those without renal improvement (73.1 vs. 39.1%). When comparing anti-C1q with antibodies against structures of DNA, significant differences were found in case of high avidity anti-dsDNA. Our results have confirmed the studies showing that anti-C1q antibodies could serve as a reliable serological marker of LN activity along with other laboratory tests. Detection of anti-C1q together with high avidity anti-dsDNA antibodies seems to be a good algorithm for the prediction of possible renal flares in SLE patients.
Biological Action of Plant Extracts on a Fungal Plant Biostimulant Strain of Trichoderma Viride
Authors: Şesan Tatiana Eugenia , Enache Elena , Iacomi Beatrice Michaela , Oprea Maria , Oancea Florin , Iacomi Cristian 
Published: January 2016

Abstract
The antifungal activity of nine plant extracts manufactured by Hofigal Import Export S.A. Romania against the biocontrol fungal agent Trichoderma viride Pers. (isolate Tv 82) was assessed in vitro for the first time in Romania. In general, the development (mycelial growth and sporulation) was not inhibited by the six plant extracts (Satureja hortensis, Achillea millefolium, Allium sativum, Mentha sp., Hyssopus officinalis, Artemisia dracunculus 'Sativa'), with three exceptions (Rosmarinus officinalis, Valeriana officinalis, Tagetes patula), applied in a concentration of 20%. Among these, the extract of Tagetes patula has inhibited the Tv 82 development, applied as lower concentrations (10% and 5%), efficacy being 54.3% and 50%, respectively. In addition, the tested plant extracts of Satureja hortensis, Achillea millefolium, Mentha sp. proved stimulative effect on Tv 82 development. This approach add to the early studies on the selectivity of Trichoderma spp. to chemicals used in plant protection, new data referring to the use of antagonistic fungi, like Trichoderma spp., as a protective mean against phytopathogens. Also, these data sustain the possibility of applying plant extracts as an alternative in plant protection or to apply together chemical (pesticides) and biological means (plant extracts) especially to protect ecological crops, as vegetables, medicinal plants a.o.
Herd-level seroprevalence of Neospora caninum infection in dairy cattle in central and northeastern Poland
Authors: Kowalczyk Sławomir J. , Czopowicz Michał , Weber Corinna N. , Müller Elisabeth , Witkowski Lucjan , Kaba Jarosław 
Published: January 2016

AbstractA serosurvey was carried out to estimate the herd-level seroprevalence of Neospora caninum infection in cattle in central and northeastern Poland. Ninety seven dairy cattle herds from 2 provinces of Poland (Podlaskie, 47 herds and Łodzkie, 50 herds) were randomly enrolled in the study using two-stage cluster method. A simple random selection was applied within each herd to select a sample of adult cows (≥18 month-old). A total number of 734 cows were enrolled in the study. The animals were screened with a commercial competitive ELISA (Bio-X Diagnostics, Belgium). To calculate true herd-level seroprevalence test sensitivity and specificity were adjusted from an individual- to a herd-level using FreeCalc method. The true overall herd-level seroprevalence of N. caninum infection was 56.7% (95% CI: 47.5%, 65.9%). The true herd-level seroprevalence in Podlaskie was 63.3% (95% CI: 43.0%, 83.6%) and 50.5% (95% CI: 32.8%, 68.2%) in Łodzkie province and these figures did not differ significantly between the two provinces (chi2 test p = 0.238). One hundred forty three of 734 cows (19.5%) were seropositive which gave the true overall individual-level seroprevalence of 20.1% (95% CI: 17.4%, 23.2%). Percentage of seropositive cows in each herd varied from 6% to 80%. This study is the first epidemiological investigation of herd-level seroprevalence of N. caninum infection in Polish dairy cattle population. In conclusion, the result of the study confirmed previous data that N. caninum infection is widespread in the Polish cattle population and thus should be considered as a potential cause of spontaneous abortions.
Expression analysis of viscerotropic leishmaniasis gene in Leishmania species by real-time RT-PCR
Authors: Nafchi Hossein Reisi , Kazemi-Rad Elham , Mohebali Mehdi , Raoofian Reza , Ahmadpour Niloofar Bavarsad , Oshaghi Mohammad Ali , Hajjaran Homa 
Published: January 2016

AbstractViscerotropic leishmaniasis (VTL) is a parasitic disease with non-specific manifestations caused by Leishmania tropica. Specific antigens produced by Viscerotropic leishmaniasis gene have been used for diagnosis of VTL. The aim of this study was to compare the expression level of VTL gene among the viscerotropic L. tropica isolates (n: 3) and visceral L. infantum isolates (n: 4). Also, the expression level was compared in L. tropica (n: 21) and L. major (n: 8) isolates, the main causes of cutaneous leishmaniasis in Iran by real time-RT-PCR. Results showed viscerotropic leishmaniasis gene was expressed in all 3 species; L. tropica, L. major and L. infantum. The most expression rate was in L. tropica and L. major as the cutaneous species and the lowest in visceral isolates including L. infantum and viscerotropic L. tropica strains respectively.Conclusion: Results revealed that VTL gene can play an important role in visceralization process of L. tropica although there are other mechanisms to keep parasite visceralized. According to these primary results, increased the expression level of VTL gene probably could contribute to inhibit the invasive behavior of Leishmania parasites. However, more experimental researches are needed to confirm this idea.
Fourier transform infrared spectroscopy as a tool for identification of crude microbial extracts with anti-malarial potential
Authors: Sankarganesh P. , Joseph Baby 
Published: January 2016

AbstractFourier transform infrared (FT-IR) spectroscopy is an indispensable tool for identifying biologically active functional groups in uncharacterized crude samples. Here, using FT-IR spectrum analysis, we identified crude extracts of Streptomyces that have anti-malarial activities and conducted a statistical analysis of their spectra. Among the three crude microbial extracts tested herein, an aromatic amine C-N stretching functional group was observed in the spectra of Streptomyces sp. BJSG1 and BJSG4 crude extracts. These extracts showed promising activity against Plasmodium falciparum in vitro cultures with IC
A 43 kDa recombinant plasmepsin elicits immune response in mice against Plasmodium berghei malaria
Authors: Pirta Chhaya , Sharma Nitya Nand , Banyal H.S. 
Published: January 2016

AbstractIntraerythrocytic parasites degrade haemoglobin to make available nutrients for their growth and maturation. Plasmepsins, the aspartic proteases of Plasmodium play a significant role in haemoglobin degradation and are proposed as attractive drug targets. In the present study the gene which encodes plasmepsin in rodent malaria parasite, Plasmodium berghei, was cloned and expressed. The gene was sequenced and expressed in Escherichia coli BL21DE3 and a recombinant plasmepsin of molecular weight 43 kDa was obtained. The sequence obtained was analysed and compared with plasmepsins of other Plasmodium spp. Mice immunized with the recombinant plasmepsin induced a strong humoral immune response. ELISA and IFA performed on the serum of immunized mice showed high antibody titres. Along with this, in vivo study exhibited partial protection against P. berghei infection suggesting role of plasmepsin in malaria control.
In search of a potential diagnostic tool for molecular characterization of lymphatic filariasis
Authors: Saeed Mohd , Adnan Mohd , Khan Saif , Al-Shammari Eyad , Mustafa Huma 
Published: January 2016

AbstractLymphatic filariasis (LF) is a chronic disease and is caused by the parasites Wuchereria bancrofti (W. bancrofti), Brugia malayi (B. malayi) and Brugia timori (B. timori). In the present study, Setaria cervi (S. cervi), a bovine filarial parasite has been used. Previously, it has been reported that the S. cervi shares some common proteins and antigenic determinants with that of human filarial parasite. The larval stages of filarial species usually cannot be identified by classical morphology. Hence, molecular characterization allows the identification of the parasites throughout all their developmental stages. The genomic DNA of S. cervi adult were isolated and estimated spectrophotometrically for the quantitative presence of DNA content. Screening of DNA sequences from filarial DNA GenBank and Expressed Sequence Tags (EST’s) were performed for homologous sequences and then multiple sequence alignment was executed. The conserved sequences from multiple sequence alignment were used for In Silico primer designing. The successfully designed primers were used further in PCR amplifications. Therefore, in search of a promising diagnostic tool few genes were identified to be conserved in the human and bovine filariasis and these novel primers deigned may help to develop a promising diagnostic tool for identification of lymphatic filariasis.
First report of Cystoisospora belli parasitemia in a patient with acquired immunodeficiency syndrome
Authors: Velásquez Jorge Néstor , Risio Cecilia Alicia di , Etchart Cristina Beatriz , Chertcoff Agustín Víctor , Nigro Mónica Gabriela , Pantano María Laura , Ledesma Bibiana Alba , Vittar Natalia , Carnevale Silvana 
Published: January 2016

AbstractCystoisospora belli in patients with the acquired immunodeficiency syndrome (AIDS) has been described as cause of chronic diarrhea and disseminated cystoisosporosis. Diagnosis of intestinal cystoisosporosis can be achieved at the tissue level in the villus epithelium of the small bowel. Disseminated cystoisosporosis is diagnosed by microscopy identification of unizoite tissue cysts in the lamina propria of the intestine. We report a case of disseminated cystoisosporosis in a human immunodeficiency virus (HIV)-infected patient with detection of parasitemia. We studied a 39-year old patient with AIDS and chronic diarrhea by analysis of stool and duodenal biopsy samples. Blood samples were also collected and examined by light microscopy and molecular techniques for C. belli DNA detection. The unizoite tissue cyst stages were present in the lamina propria, with unsporulated oocysts in feces. Zoites were present in blood smears and DNA of C. belli was detected in blood samples. Our study identified a new stage in the life cycle of C. belli. Detection of parasitemia is a novel and noninvasive tool for diagnosis of disseminated cystoisosporosis.
The transstadial persistence of tick-borne encephalitis virus in Dermacentor reticulatus ticks in natural conditions
Authors: Karbowiak Grzegorz , Biernat Beata , Werszko Joanna , Rychlik Leszek 
Published: January 2016

AbstractThere are a number of reports regarding natural infection of Dermacentor reticulatus ticks with TBE virus; however, the transmission mode of TBE virus in this tick population has not been investigated. This study was conducted in Białowieża Primeval Forest, east Poland. Forty fully engorged nymphs of D. reticulatus were sampled from root voles (Microtus oeconomus). Ticks were kept until molting. All ticks were screened for the presence of TBE virus by nested RT-PCR. Three adult ticks were positive for infection with TBE virus. The present study for the first time demonstrates the possibility of transstadial mode of TBEV transmission in D. reticulatus ticks.