bluuebunny/crossref_metadata_2025_split huggingface dataset:
تأثير التسويق الإلكتروني في تعزيز الصحة واللياقة دراسة استطلاعي لآراء عينة عشوائية من مستخدمي تطبيقات الصحة واللياقة الإلكترونية والمحتوى الرقمي
Authors: حسين رحيمي كلور  , مها عارف بريسم  , مها عارف بريسم  , صادق محمد ورد  
Published: October 2024

تناولت هذه الدراسة تحليل التأثير الذى يقوم به التسويق الالكترونى فى تعزيز الصحه واللياقه البدنيه، عن طريق استخدام المحتوى الرقمى والتطبيقات من اجل العمل على تحفيز السلوك الصحى. اعتمدت الدراسة على منهج تحليلي ووصفي، حيث استخدمت استبانة إلكترونية لجمع البيانات من مشاركين من مختلف محافظات العراق. كانت أهداف الدراسة تحليل تأثير استخدام تطبيقات اللياقة والتفاعل مع المحتوى الرقمي، وكذلك فحص تأثير حملات التسويق الإلكتروني على تبني عادات حياة صحية. اعتمد الدراسة المنهج التحليلي الوصفي، حيث تم جمع البيانات من خلال استبانة إلكترونية، متبعةً في تحليلها البرنامج الإحصائي SPSS Ver.23. اتسمت الاستبانة ب 15 سؤالاً متعدد الاختيارات، ثم تم فحص علاقات التأثير والارتباط بالاستعانة باختبار ANOVA واختبار Correlation Test:وفي النهاية تم التحقق من الفرضيات والإجابة عن الأسئلة الدراسة بنجاح، حيث أظهرت النتائج تأثيرًا معنوياً بين التسويق الإلكتروني باستخدام التطبيقات ومحتواه الرقمي وبين تعزيز السلوك الصحي ومعدل النشاط البدني. ختمت الدراسة بتأكيد أهمية تبني استراتيجيات التسويق الرقمي في تعزيز الصحة واللياقة البدنية بفاعلية.
English Vocabulary Learning System Web Based Using Rapid Application Method
Authors: Aprinia Handayani  , Samsoni  
Published: October 2024

English lexicon dominance is one of the imperative viewpoints in dialect learning at the Kindergarten (TK) level. Be that as it may, ordinary strategies utilized in lexicon learning are frequently less curiously and less successful in spurring understudies to memorize. The foundation of this think about is the require for a more interactive learning framework that's in understanding with innovative advancements to back the educating and learning handle at TK Al Amanah. The issue confronted is how to plan a lexicon learning framework that can increment students' intrigued and understanding successfully. As a arrangement, this consider proposes the improvement of a web-based English lexicon learning framework utilizing the Fast Application Advancement (RAD) strategy. The RAD strategy was chosen since it is able to create quick models and include clients in each organize of improvement, so that the coming about system can be more in agreement with the requirements of clients, in this case understudies and instructors at TK Al Amanah. The framework developed includes highlights such as intelligently works out, advanced flashcards, and tests planned to create it simpler for understudies to memorize and get it lexicon. The investigate strategy includes needs examination, framework plan, model advancement, testing, and assessment. The trial comes about appear that this framework isn't only able to extend understudy inspiration and interest, but too gives comfort for instructors in conveying learning materials. Hence, this web-based learning framework offers an innovative solution that can bolster the method of educating English lexicon at the kindergarten level
POTENCIAL FISIOLÓGICO DE SEMENTES DE SOJA EM FUNÇÃO DO TAMANHO
Authors: Martins de Santana Douglas , De Lima Saraiva Éria Rafhaela , Borges de Sousa Diego , Oliveira Diniz Fábio 
Published: October 2024

O tamanho da semente e sua relação com o potencial fisiológico vêm sendo estudados por diversos autores. O percentual de germinação entre diferentes lotes pode estar ligado às condições ambientais adversas durante a etapa de produção, mal formação, incidência de pragas e doenças e deterioração advinda do atraso na colheita ou armazenamento. Porém, não há consenso quanto aos resultados demonstrados. Neste sentido, este estudo foi conduzido com o objetivo de avaliar o potencial fisiológico de sementes de soja em função do tamanho. Para tanto, foram utilizadas sementes de três cultivares de soja: NEO 760, NEO 810 i2x e FTR 3191 IPRO. Cada cultivar foi representada por três lotes e classificadas em dois tamanhos de peneiras (5,5 e 6,5 mm de diâmetro). O delineamento experimental utilizado foi inteiramente casualizado, sendo os tratamentos em esquema fatorial 3 x 2 (lote e nº da peneira, respectivamente), com quatro repetições de 50 sementes para cada teste. Os testes para determinação do potencial fisiológico foram realizados imediatamente após a colheita e após 90 dias de armazenamento. Foram avaliadas as seguintes variáveis: germinação em papel, viabilidade e vigor em tetrazólio, germinação em areia e envelhecimento acelerado. Os dados foram submetidos à análise de variância pelo teste F e as médias comparadas pelo teste de Tukey (p < 0,05). Não foi evidenciada a relação direta entre o tamanho das sementes de soja e o potencial fisiológico para nenhuma das cultivares analisadas neste ensaio
Pembuatan Tepung Biji Mangga (Mangifera indica L.) dengan Metode Blanching dan Penambahan Asam Askorbat
Authors: Tungga Hayu Nirmala Cipta , Safira Cecilia Z  , Widji Triana Nurul , Suprihatin  
Published: October 2024

Biji mangga memiliki kandungan protein (7,5 – 13%), karbohidrat (69,2 - 80%), kalsium (0,21%), abu (2,2 –2,6%), fosfor (0,22%) dan serat (2,0 – 4,6%). Oleh karena itu, biji mangga dapat diolah menjadi bahan pangan yang potensial. Tujuan penelitian yaitu membuat tepung biji mangga, mengetahui pengaruh waktu blanching serta konsentrasi asam askorbat terhadap kandungan karbohidrat, lemak, protein, kadar air dan sensori tepung biji mangga. Pembuatan tepung biji mangga melalui tahapan diantaranya pengupasan kulit, pencucian biji, pemotongan tebal 0,5 cm, penimbangan, blanching 85℃ selama (0; 2,5; 5; 7,5; 10) menit, perendaman 30 menit dengan Na-metabisulfit 0,2%, perendaman dengan 20 menit dengan asam askorbat (0; 0,5; 1; 1,5; 2)%, pengeringan (80℃, 4 jam), penghalusan, pengayakan 80 mesh. Hasil penelitian menunjukkan semakin lama waktu blanching, kadar karbohidrat, protein dan air tepung biji mangga semakin meningkat, sedangkan kadar lemak semakin menurun. Konsentrasi asam askorbat semakin tinggi juga meningkatkan kadar karbohidrat, dan protein tepung, namun menurunkan kadar air dan lemaknya. Perlakuan blanching dan perendaman asam askorbat pada biji mangga berpengaruh nyata terhadap warna tepung (p<0,05), namun berpengaruh tidak nyata pada aroma dan tekstur tepung (p>0,05).

Mango seeds contais protein (7.5 - 13%), carbohydrate (69.2 - 80%), calcium (0.21%), ash (2.2 -2.6%), phosphorus (0.22%) and fiber (2.0 - 4.6%). Mango seeds can be processed into potential food. The objectives of the study were to make mango seed flour, determine the effect of blanching time and ascorbic acid concentration on the content of carbohydrates, fat, protein, water content, and sensory of mango seed flour. Steps to make mango seed flour including peeling and washing the seeds, cutting 0.5 cm thick, weighing, blanching at 85℃ for (0; 2.5; 5; 7.5; 10) minutes, 30 minutes soaking with Na-metabisulfite 0.2%, immersion with 20 min with ascorbic acid (0; 0.5; 1; 1.5; 2)%, drying (80℃, 4 hours), pulverization, 80 mesh sieving. Research result showed that the longer the blanching time, carbohydrate, protein and water content of mango seed flour increases, while the fat content decreases. The higher ascorbic acid concentration also increased the carbohydrate and protein content of flour, but decreased the water and fat content. Blanching treatment and ascorbic acid soaking treatment on mango seeds had a significant effect (p<0,05) on the color of the flour, but did not significantly affect the aroma and texture of flour(p>0,05).
Impact of Cyclophosphamide on Testis and Sexual Glands of Adult Albino Rats and Probable Recovery After Drug Withdrawal: A Histological and Immunohistochemical study
Authors: Sheet Eman Ghanim 
Published: October 2024

السايكلوفوسفامايد هو علاج كيميائي معروف ودواء مضاد للمناعة ويستخدم على نطاق واسع في علاج الأمراض الخبيثة والمتعلقة بالمناعة. تم إجراء العمل الحالي لتقييم التركيب النسيجي للغدد التناسلية الذكرية أثناء العلاج وبعد التوقف عن تناول هذا الدواء.
المواد والطرق: تم تصنيف ثلاثون من ذكور الجرذان إلى ثلاث مجموعات. عولجت المجموعة الأولى بمحلول ملحي عادي، بينما عولجت المجموعة الثانية والمجموعة الثالثة بالسايكلوفوسفاميد 150 مجم / كجم داخل التجويف الصفاقي كل يومين لمدة أسبوع. المجموعة الثالثة اعتبرت مجموعة التعافي وتم تقسيمها إلى مجموعتين فرعيتين مع فترة تعافي لمدة شهرا وشهرين. في نهاية العمل تم سحب الدم لأجراء فحص هرمون التستوستيرون ثم تم قتل الحيوانات وإزالة كل من الخصية، البروستات والحويصلة المنوية وتحضير العينات للصبغات النسيجية والنسيجية المناعية.
النتائج: أظهرت المجموعة المعالجة (المجموعة الثانية) بالسايكلوفوسفاميد انخفاضًا في مستوى هرمون التستوستيرون في الدم، وكشفت مقاطع الخصية والغدد الجنسية عن تغيرات ضامرة وتنكسيه في الظهارة البطانية مع انخفاض وظيفتها وتغيرات في تعبيرها المناعي مما يشير إلى نمط تكاثر غير طبيعي للخلايا. ومع ذلك، فإن التغيرات النسيجية المرضية للمجموعة المعالجة لم تظهر أي تحسن بعد شهر أو حتى شهرين من سحب الدواء
الاستنتاج: أشارت الدراسة الحالية إلى خطر العقم وسمية الغدد التناسلية أثناء العلاج بالسيكلوفوسفاميد والذي قد يكون دائما حتى بعد انتهاء العلاج.
Rate of Adriamycin Resistance Associated (ARA) long Noncoding RNA Expression in Sample of Hepatitis B Virus Iraqi Patients
Authors: Osama Mohammed Hasan  
Published: October 2024

تم ربط العديد من العمليات البيولوجية، بما في ذلك تنظيم الوراثة اللاجينية، والتحكم في دورة الخلية، إلى جانب النسخ والانتقال وتنظيم التعبير الجيني، بـ lncRNAs الطويلة غير المشفرة، ومن المفهوم أن تعطيل الأنظمة التنظيمية للتعبير عن lncRNAs يعد مراحل مبكرة مهمة في نشأة الاورام. توجد حالة من عدم المعرفة فيما يتعلق بوظيفة lncRNAs في مرض فيروس التهاب الكبد B. تم إجراء تضخيم ARA Lnc-RNA وGAPDH الجين المرجعي بواسطة Two Steps reverase-Transcriptase PCR، ولم يلاحظ أي فرق كبير P = 0.566 في مستويات مصل ARA lncRNA بين مريض فيروس التهاب الكبد B المزمن والسيطرة عليه، في مجموعة المرضى الذين يعانون من فيروس التهاب الكبد B المزمن. ، مع ملاحة رفع التعبير عن ARA lncRNAs إلى مرتين.
Comparative Performance Analysis of Catalysts for Syngas Production from Biogas: A Simulation Study Using DWSIM
Authors: Adha Afdal , Rahmadi Arie 
Published: October 2024

This study explored how CH4/CO2 feed ratio, temperature, and pressure affect the conversion of carbon dioxide and methane and the H2/CO ratio of syngas using simulations for six catalysts: Rh/La2O3, Rh/La2O3-SiO2, Ru/La2O3, Ni-Co/Al-Mg-O, LaNiO3, and Ce-La-Ni-O2. Simulations with DWSIM© were conducted at CH4/CO2 feed ratios of 1–2, pressures of 1–5 bar, and temperatures of 550–750 °C. The effects showed that increasing the temperature by as much as 750 °C boosted the H2/CO ratio and improved CO2 and CH4 conversions because of the endothermic nature of the reactions. Higher pressure reduced conversion rates and H2/CO ratios across all catalysts, with a notable similarity between 2 and 5 bar, indicating thermodynamic limits. A higher feed ratio of CH4/CO2 decreased CH4 conversion while increasing the H2/CO ratio at the expense of reduced H2 yield. As the pressure decreases, the Ru/La2O3 and Rh/La2O3-SiO2 catalysts exhibited higher activity because of the kinetic factor. The current research focuses on the possibility of using dry reforming of biogas to synthesize syngas with suitable H2/CO ratios for different uses. The observations suggest that future studies should include techno-economic analysis to determine the least expensive catalysts that will ensure the dry reforming process yields the right composition of syngas.
Elderly Care Provision under National Policy on Older Persons 2013: A Cross-Sectional Study in Dhaka City, Bangladesh
Authors: Khatun Khadiza , Halim Sadeka 
Published: October 2024

Bangladesh is undergoing a notable demographic transition, characterized by a substantial rise in the proportion of elderly individuals within its population. This demographic transition presents a range of economic, social and cultural issues that necessitate prompt attention and intervention. The aim of this study was to examine the current state of elderly care services and facilities available for older adults in urban landscape by taking into account the ‘National Policy on Older Persons 2013.’ This study was conducted in Dhaka city by employing a cross-sectional study design. The study population covers elderly people aged 60+ years, living in Dhaka City for more than five years continuously and are able to speak well with someone. The study was based on a sample of 240 and the respondents were chosen using convenient sampling technique. The data were collected through face-to-face interview using structured questionnaire and they were analyzed utilizing descriptive statistics. This study found that the existing elderly care services and available opportunities are below the satisfactory level for most of the older adults of the city, even though the ‘National Policy on Older Persons 2013’ was adopted a decade ago. The elderly people in Dhaka city encountered a number of difficulties considering their physical health, psychological and social well-being. In the case of availability of the affordable and quality healthcare services for older adults in their community, 30.4% of the respondents said that the availability, accessibility and affordability of quality healthcare services are very poor, followed by 24.6% below average and 26.3% at the average level. Nearly 75% of the study people said that they had ever experienced unfair treatment for being aged. Indeed, they receive care and support in an inconsistent, disorganized and incoherent manner. The study clearly revealed that there is a need to prioritize person-centered care as well as integrated care system for the effective management of the ageing population in Bangladesh.
Jagannath University Journal of Science, Volume 11, Number 1, June 2024, pp. 118−134
Immunological, Serological and Hematological Changes in COVID 19 Patients of Dhaka City
Authors: Akter Amena , Biswas Bishyajit Kumar , Bepary Sukumar 
Published: October 2024

The analytical test reports of COVID-19 patients admitted in two major hospitals in Dhaka City were analyzed to observe the immunological, serological and hematological abnormalities that can be significant for managing the patients in emergencies. The observed levels of ferritin, procalcitonin, D–Dimer, C-reactive protein (CRP), creatinine and alkaline phosphatase (Alkp) were taken into consideration for this study. Though these parameters were elevated as mentioned for patients from many other countries, in significant cases, the values were normal or even lower than the normal levels. The ferritin level was normal (For men, 24 to 336 micrograms per liter. For women, 11 to 307 micrograms per liter) in only 30% of the patients, whereas, 50% of the patients had higher values and 20% patients had the lower values. Similarly, the procalcitonin (normal value 0.1 to 0.5 ng/mL) level was found to be normal in only 27% of the patients while remaining 73% patients had the high level of this parameter. The D‑Dimer level (less than 0.50) was also found to be normal in only 27% of the patients, whereas 72% of the patients had the higher levels. The C‑reactive protein was within the normal level in only 22% of the patients, whereas, 76% of the patients had the high level of this marker. The creatinine was found to be increased in 60% of the patients. There were 88% patents having increased levels of Alkp with only 12% patients having normal levels. Thus, the elevations of the immunological, serological and hematological parameters were somehow different from those observed from patients in other countries. This information might be useful in managing the hospitalized COVID-19 patients in our country.
Jagannath University Journal of Science, Volume 11, Number 1, June 2024, pp. 203−207
Quantification of muscle fiber malformations using edge detection to investigate chronic muscle pressure ulcers
Authors: Ong Charlene Z. L. , Nasir N. Jannah M. , Welsch Roy E. , Tucker-Kellogg Lisa , Rajapakse Jagath C. 
Published: October 2024

BackgroundMicroscopy of regenerated tissue shows different morphologies between the healing of acute wounds and chronic wounds. This difference can be seen manually by biologists, but computational methods are needed to automate the characterization of morphology and regenerative quality in regenerated muscle tissue.ResultsFrom the detected edge segments, we computed several imaging biomarkers of interest, such as median tortuosity, number of edge segments normalized by area, median edge segment distance and interquartile range of orientation angles of edge segments of the microscope images of successful and unsuccessful muscle regeneration. We observed that muscle fibers in saline-treated pressure ulcers had a larger interquartile range of orientation angles of the edge segments (p = 0.05) and shorter edge segment distances (p = 0.003) compared to those of acute cardiotoxin injuries.ConclusionOur edge detection method was able to identify statistically significant differences in some of the imaging biomarkers between saline-treated pressure ulcers and cardiotoxin injuries, suggesting that chronic pressure ulcers have increased muscle fiber malformations compared to cardiotoxin injuries.
Quantifying the impact of a constructed wetland on downstream nitrate concentrations and loads in the U.S. Midwest
Authors: Anderson Elliot , Schilling Keith E. , Just Craig L. , Seo Bong Chul 
Published: October 2024

Constructed wetlands are standard conservation practices used to reduce nitrate loads in agricultural watersheds. Many studies have examined the efficiency of denitrification in wetlands under various scenarios, but quantifying the watershed-scale impact of wetlands on downstream nitrate levels is rarely done using field observations. In this study, we estimated nitrate removal in a constructed wetland in the headwaters of Mud Creek, a HUC12 watershed in eastern Iowa, from May–September 2022 and May–September 2023 (a ten-month period). We also measured nitrate loads at four successive downstream sites, three along Mud Creek and one below its confluence with the larger Cedar River. The wetland removed 6,200 kg of nitrate (74% of total inputs). At the three downstream locations in Mud Creek, the percentage of each site’s total nitrate load removed by the wetland decreased to 19, 8.6, and 4.1%—this latter value represents the wetland’s influence on nitrate removal in the entire Mud Creek basin. The wetland’s impact of nitrate loads in the Cedar River was negligible (reduction of 0.02%). The percentage of a site’s drainage area treated by the wetland approximately followed a 1:1 relationship to that site’s percent reduction in nitrate. Profiles of nitrate concentrations in Mud Creek notably varied pre- and post-wetland. Concentrations before the installation steadily decreased along the waterway, while post-wetland concentrations rapidly decreased directly downstream of the wetland and steadily increased at each succeeding site. Our results demonstrate that while the wetland successfully lowered local nitrate levels, its effect on the basin’s overall nitrate loads was minimal. Achieving nutrient reduction goals at the watershed scale solely using constructed wetlands appears infeasible given that the required number of practices greatly exceeds current efforts.
Clinical ocular prediction model of postoperative ametropic amblyopia in patients with congenital ectopia lentis
Authors: Wang Xinyue , Song Linghao , Liu Yan , Huo Qiuyi , Sun Yang , Chen Zexu , Jia Wannan , Shen Xin , Wang Yalei , Chen Xinyao , Chen Tianhui , Jiang Yongxiang , Wang Rui 
Published: October 2024

IntroductionDespite prompt and appropriate surgical management, a considerable proportion of patients with congenital ectopia lentis (CEL) suffer from postoperative ametropic amblyopia. To predict and identify at-risk patients early, and ensure timely amblyopia treatment, we conducted a thorough investigation into the onset and progression patterns of postoperative amblyopia in patients with CEL. Moreover, an ocular prediction model was constructed for amblyopia.MethodsIn this prospective cohort study, amblyopia analysis was conducted to reveal the prevalence of postoperative amblyopia at different time points of follow-up. Comparative analysis and logistic regression analysis were performed for the development of an amblyopia prediction model. Receiver Operating Characteristic (ROC) analysis, calibration plots, and decision curve analysis (DCA) were used to evaluate the performance of the model. A nomogram was created to determine the probability of postoperative amblyopia. Amblyopia was diagnosed according to the most recent edition of the Amblyopia Preferred Practice Pattern.ResultsA total of 889 eyes from 677 patients operated for CEL were enrolled in this study. In the pediatric cohort, the prevalence of amblyopia showed a decreasing trend with follow-up time from 1 month to 3.5 years. A prediction model based on preoperative best-corrected visual acuity (BCVA) and cardiac phenotype was established to predict postoperative amblyopia. For effective individual prediction, a nomogram was created. With great calibration, discrimination, and clinical usefulness, the prediction model demonstrated good performance.ConclusionThe findings underscore that the prevalence of ametropic amblyopia in pediatric CEL patients who underwent lens surgery exhibited a marked decline over time. The prediction model established with preoperative BCVA and cardiac phenotype can provide accurate and individualized predictions of postoperative amblyopia, and it has the potential to assist ophthalmologists in rapidly identifying high-risk patients.
TLR4-mediated chronic neuroinflammation has no effect on tangle pathology in a tauopathy mouse model
Authors: Basheer Neha , Muhammadi Muhammad Khalid , Freites Carlos Leandro , Avila Martin , Momand Miraj Ud Din , Hryntsova Natalia , Smolek Tomas , Katina Stanislav , Zilka Norbert 
Published: October 2024

IntroductionAlzheimer’s disease (AD) is marked by the accumulation of fibrillary aggregates composed of pathological tau protein. Although neuroinflammation is frequently observed in conjunction with tau pathology, current preclinical evidence does not sufficiently establish a direct causal role in tau tangle formation. This study aimed to evaluate whether chronic Toll-like receptor 4 (TLR4) stimulation, induced by a high dose of lipopolysaccharide (LPS, 5 mg/kg), exacerbates neurofibrillary tangle (NFT) pathology in a transgenic mouse model of tauopathy that expresses human truncated 151-391/3R tau, an early feature of sporadic AD.MethodsWe utilized a transgenic mouse model of tauopathy subjected to chronic TLR4 stimulation via weekly intraperitoneal injections of LPS over nine consecutive weeks. Neurofibrillary tangle formation, microglial activation, and tau hyperphosphorylation in the brainstem and hippocampus were assessed through immunohistochemistry, immunofluorescence, and detailed morphometric analysis of microglia.ResultsChronic LPS treatment led to a significant increase in the number of Iba-1+ microglia in the LPS-treated group compared to the sham group (p &lt; 0.0001). Notably, there was a 1.5- to 1.7-fold increase in microglia per tangle-bearing neuron in the LPS-treated group. These microglia exhibited a reactive yet exhausted phenotype, characterized by a significant reduction in cell area (p &lt; 0.0001) without significant changes in other morphometric parameters, such as perimeter, circumference, solidity, aspect ratio, or arborization degree. Despite extensive microglial activation, there was no observed reduction in tau hyperphosphorylation or a decrease in tangle formation in the brainstem, where pathology predominantly develops in this model.DiscussionThese findings suggest that chronic TLR4 stimulation in tau-transgenic mice results in significant microglial activation but does not influence tau tangle formation. This underscores the complexity of the relationship between neuroinflammation and tau pathology, indicating that additional mechanisms may be required for neuroinflammation to directly contribute to tau tangle formation.