bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Helicobacter pylori genotypes in patients with gastroduodenal pathology in Kazan
Authors: Akhtereeva A R , Davidyuk Yu N , Faizullina R A , Ivanovskaya K A , Safin A G , Safina D D , Abdulkhakov S R 
Published: October 2017

Aim. Investigation of the prevalence of various H. pylori genotypes among children and adult population of Kazan with chronic gastroduodenal pathology.
Methods. The study included 107 patients (49 children and 58 adults) with chronic gastritis/gastroduodenitis and gastric and duodenal ulcer who had H. pylori infection confirmed by molecular genetic method. All patients underwent biospy from antral mucosa during endoscopy for H. pylori verification by polymerase chain reaction and genotyping for сagA and babA genes and iceA and vacA allels.
Results. CagA gene was found in 19 (32.8%) out of 58 adults and 13 (26.5%) out of 49 children. VacA gene was detected in all patients (100%). VacAs2 genotype in children was nearly 1.6 times as frequent as the vacAs1 genotype (61.2 and 36.7% respectively). In adult patients vacAs2 genotype was detected 2.5 times less frequently than vacAs1 (27.6 and 70.7%, respectively). VacAm2 genotype was revealed in 71.4% (35/49) of children and 77.6% (45/58) of adults. IceA2 genotype was identified in 46.9% (23/49) of children and 44.8% (26/58) of adult patients, iceA1 gene - in 20.4% of children and 55.2% of adult patients.
Conclusion. The strains with vacAs2m2 genotype are prevailing in children (42.9%) and determine low toxigenicity of H. pylori strains; vacAs1m2 genotype is predominant among adult patients (53.4%); high prevalence of cagA-negative strains of H. pylori was found both in children and adults (73.5 and 67.2%, respectively).
The peculiarities of focal epilepsy in pregnant women
Authors: Melikova Sh Y 
Published: October 2017

Aim. To investigate the peculiarities of focal epilepsy in pregnant women.
Methods. 70 pregnant women with symptomatic focal epilepsy during the period from 2013 to 2017 were studied.
Results. The average age at the onset of epilepsy was 18.2±0.6 years. The average duration of epilepsy by the time of pregnancy was 6.6±0.7 years. 15 (21.4±4.9%) women remained seizure-free during pregnancy. Seizures during pregnancy were observed in 55 (78.6±4.9%) women: seizure frequency increased in 22 (31.4±5.5%) cases, decreased in 17 (24.3±5.1%), remained unchanged in 8 (11.4±3.8%), in 8 (11.4±3.8%) women the onset of epilepsy occurred during pregnancy. 72.7% of women who were seizure-free for 1 year prior to pregnancy remained seizure-free during pregnancy. In 21 (40.4%) of 52 women with epilepsy diagnosed prior to pregnancy and treated with antiepileptic drugs, the increase of seizure frequency was observed, which can be explained by non-compliance with the regimen and therapy and sleep deprivation in 15 (71.4%) of them. Generalized convulsive status epilepticus during pregnancy was observed in 1 (1.4±1.4%) woman after a sudden withdrawal of the antiepileptic drug.
Conclusion. The risk of seizures during pregnancy is lower in women who were seziure-free for 1 year prior to pregnancy; non-compliance with the regimen and therapy and sleep deprivation may lead to worsening of epilepsy during pregnancy.
Efficacy of Sodium deoxyribonucleate in community-acquired pneumonia in children of school age
Authors: Pikuza O I , Fayzullina R A , Suleymanova Z Ya , Zakirova A M , Serdinskaya I N 
Published: October 2017

Aim. To study efficacy of sodium deoxyribonucleate use for the treatment of community-acquired pneumonia in children of school age.
Methods. 102 children aged 7 to 17 years were observed: 25 relatively healthy children (control group), 39 children with community-acquired pneumonia, who received only conventional treatment (comparison group) and 38 patients with community-acquired pneumonia receiving complex treatment with additional sodium deoxyribonucleate (study group). All patients underwent clinical and instrumental and laboratory examination. Cytomorphologic features of neutrophils and epithelial cells, cytokine concentration (interleukin-8, -10 and -17, tumor necrosis factor α) were examined in nasal secret of patients with community-acquired pneumonia dynamically on different therapy regimens. Evaluation of dynamics of clinical signs was performed in the studied groups.
Results. In the study clinical efficacy of the medication was discovered and caused decreased disease duration, acceleration of inflammatory changes reparation in the lungs in rhinocytogram, decreased level of neutrophils and their destructive forms, decreased levels of pro-inflammatory cytokines - interleukin-8 and tumor necrosis factor α.
Conclusion. Sodium deoxyribonucleate enhances adaptive resources of mucosal immunity, leads to restoration of epithelium lining the upper respiratory airways and therefore potentiates local immunity.
Determining the efficacy of complex conservative treatment of chronic constipation in children
Authors: Polukhov R S 
Published: October 2017

Aim. Evaluation of the effectiveness of complex conservative treatment of chronic constipation in children of different age groups.
Methods. Results of conservative treatment for chronic constipation in 574 children in different age groups are presented in the article. 321 of those were assigned to traditional treatment (group 1), while 248 were assigned consecutively to metronidazole, intesti-bacteriofague, probiotics along with traditional treatment for more adequate therapy; to magnesium orotate - to correct microcirculatory disorders and tissue dysplasia; to prevent and treat endogenic intoxication and secondary hepatic disease - to glutathione (group 2). The treatment was conducted for a year by courses in months 1, 2, 3, 6, 9 and 12 (total of 6 courses). If ineffective, follow-up treatment was provided: within 2 years - quarterly (4 courses) and during the third year - once in 6 months (2 courses).
Results. Compared to traditional treatment the results of the suggested complex treatment were sifgnificantly better; the best results were achieved in age group 3-7 years; stable and positive result was achieved already by the end of the first year of suggested complex treatment, and with traditional approach the duration of treatment was up to 3 years.
Histologic investigation of cytotoxicity of nanocomposite particles used for direct restorations in dentistry in rat models
Authors: Gimaletdinova A M , Saleeva G T , Boychuk N V , Abdul’yanov V A , Saleev R A 
Published: October 2017

Aim. To study cytotoxicity of glass-ionomer cement 3MTMESPETMVitremer, nanocomposite for direct restorations 3MTMESPETMFiltekTMUltimate and nanocomposite particles 3MTMESPETMFiltekTMUltimate in the experiment with laboratory male Wistar rats.
Methods. The experimental animals in precervical region of the first left superior molar had a cavity formed with the use of dental drill, which was filled with glass-ionomer cement 3MTMESPETMVitremer, nanocomposite for direct restorations 3MTMESPETMFiltekTMUltimate or nanocomposite particles 3MTMESPETMFiltekTMUltimate. On day 14 the animals were removed from the experiment, and sample of gingiva adjucent to the formed tooth cavity and sample of gingiva from the opposite side of dental arch were taken. Paraffin sections of the samples were prepared and were straightaway placed on a glass slide. For histologic study deparaffinized sections were stained with hematoxylin and eosin and immunohistochemical test with the use of primary antibodies to macrophage marker CD68, marker of cell proliferative activity Ki-67, mesenchymal marker vimentin, endothelial cell membrane antigen CD34 and cytokeratin CKP-PAN.
Results. The results proving cytotoxic effect of nanocomposite particles 3MTMESPETMFiltekTMUltimate on the tissues surrounding teeth, were received. On the operated and contralateral sides morphologic changes of mucosa were found including the signs of inflammation, hyperkeratosis, and cell proliferative activity. Changes of gingival mucosa are mostly pronounced in animals whose tooth cavity was filled with nanocomposite particles.
Conclusion. Taking into account the negative effect of nanocomposite particles discharging at erosion on gingival mucosa, we consider it reasonable to limit the use of the studied materials on occlusal surfaces exposed to heavy mechanical load leading to intensive erosion.
Prospects for the use of direct antioxidant ionol (2,6-di-tert-butyl-4-methylphenol) for conservative treatment of cataract
Authors: Kolesnikov A V 
Published: October 2017

Aim. To estimate the effect of ionol (2,6-di-teRt-butyl-4-methylphenol) on the dynamics of lens opacities and its free-radical status in experimental cataract.
Methods. Cataract was induced by a single injection of diquat dibromide solution into the vitreous body of 80 rabbits (160 eyes) at a dose of 600 nmol, 5 rabbits were included into the control intact group. Animals with induced cataract were divided into 4 groups each including 20 animals (40 eyes) who were treated with TID instillation in conjunctival cavity of: olive oil (control), «Oftan Catachrom», solution of α-tocopherol acetate, 2.2% ionol oil solution. Treatment was started on day 7. The duration of the experiment was 56 days. Dynamics of lens opacities was assessed by the following criteria: progress, stabilization and regression. In the lens homogenate the concentration of malonic dialdehyde, level of non-protein thiol (SH) groups, activity of glutathione peroxidase and glutathione transferase were determined. The results were analyzed by ANOVA, paired comparison was performed by the Newman-Keysl criterion.
Results. Application of ionol reduced malonic dialdehyde concentration in the lens compared to the series without treatment on days 14, 28, 42 and 56 (by 74.3, 90.0, 89.3, and 80.2%, p
Blood coagulation system in chronic benzene poisoning via inhalation
Authors: Oruzhov R A , Zhafarova R A 
Published: October 2017

Aim. To experimentally study the changes occurring in blood coagulation system in exposure to low-dose benzene.
Methods. The experiment was performed on 36 rabbits by chronic exposure of the animals to benzene during 4 months on a daily basis 4 hours a day with 1 non-exposure day a week and a one-month recovery period after the end of exposure. The average poisoning concentration of benzene in the chambers was between 1240±82 mg/m3. The animals were divided into three groups: group 1 was exposed to gradually increasing concentration of benzene, group 2 - to fluctuating (intermittent) concentrations of benzene, group 3 included unexposed to benzene animals and was used as the control group. Overall blood clotting activity, blood clotting time, blood clot retraction, plasma recalcification time, plasma tolerance to heparin, prothrombin index, fibrinogen concentration, blood fibrinolytic activity were determined.
Results. In a month after exposure blood clot retraction rates in groups 1 and 2 increased by 79.8 and 23.1% respectively. Plasma tolerance to heparin most significantly changed in animals from group 2 (by 15.4%). Prothrombin time increased by 11.4% in group 1 while in group 3 this parameter decreased by 0.4%. Prothrombin index in group 1 decreased by 4.3%, and in group 2 the changes were not statistically significant. Concentration of fibrinogen in the blood in group 1 had no significant changes and decreased by 4.2% while in group 2 it decreased by 10.4%. Fibrinolytic activity in group 1 and 2 decreased by 47.5 and 5.8% respectively.
Conclusion. The studied benzene concentrations impair blood coagulation and anti-coagulation systems including two stages of hemostasis: 1st stage - from factor XII activation, 2nd stage - from prothrombin (factor II) activation.
A method of treatment of knee hemosynovitis after arthroscopic meniscal resection
Authors: Vasil’ev V N , Novikov A V 
Published: October 2017

Aim. Optimization of the treatment of patients with knee hemosynovitis after arthroscopic meniscal resection in early postoperative period.
Methods. The results of treatment of 79 patients aged 18 to 60 years, who underwent arthroscopic meniscal resection complicated by knee hemosynovitis, were analyzed. Out of them, 38 patients underwent the treatment according to authors’ method (group 1) which included joint drainage with +5 °С isotonic solution of Sodium hydrocarbonate until the solution ran clear, and intraarticular administration of a cocktail of 5% Ascorbic acid solution for injections, 5% Sodium dimercaptopropansulfonate (unithiol) and 0.5% procaine (novocaine) in a ratio 1:1:1. 41 patients (group 2) received traditional treatment - only tapping and intraarticular administration of 3 ml of 0.5% procaine (novocaine). To assess the efficacy of treatment, severity of edema and pain syndrome, results of MRI on days 3 and 7 after arthroscopy, hydrogen ion concentration, relative density, lipid hydroperoxide level, total SH-groups, cytosis and synovial cytogram of hemosynovial fluid were measured, as well as the number of punctures, hospital stay and survey results of 45 patients.
Results. Surgical intervention was found to lead to inflammation, decreased hydrogen ion concentration, increased lipid peroxidation and decreased thiol antioxidants concentration. The severity of these changes correlates with severity of clinical manifistations. In the early postoperative period inflammatory processes develop in the knee, which clinically manifest as hemosynovitis, occurrence of which after arthroscopic meniscal resection is 16%.
Conclusion. The developed method of the treatment of postoperative hemosynovitis leads to faster decrease of severity of lipid peroxidation, pain syndrome and inflammatory reaction as opposed to traditional treatment.
Crescimento e componentes de produção do algodoeiro colorido submetido ao estresse salino e adubação potássica
Authors: Capitulino Jéssica Dayanne , Silva André Alisson Rodrigues da , Lima Geovani Soares de , Farias Maria Sallydelândia Sobral de , Nascimento Héraclito Marques do , Soares Lauriane Almeida dos Anjos 
Published: October 2017

<p>Objetivou-se avaliar o crescimento e os componentes de produção do algodoeiro colorido cv. BRS Topázio, em função da irrigação com águas de diferentes níveis de salinidades e doses de potássio. O experimento foi conduzido em casa de vegetação, utilizando-se um Neossolo Regolítico Eutrófico de textura franco-arenosa não salina no município de Campina Grande, Paraíba. Adotou-se o delineamento de blocos casualizados esquema fatorial 4 x 4 em com três repetições, cujos tratamentos foram constituídos de quatro níveis de condutividade elétrica da água de irrigação (1,5; 3,0; 4,5 e 6,0 dS m<sup>-1</sup>) e quatro doses de potássio (50; 75; 100 e 125% da recomendação ), sendo a dose de 100% correspondente a 150 mg K<sub>2</sub>O por kg<sup>-1</sup> de solo. A salinidade da água de irrigação afetou negativamente o crescimento do algodoeiro cv. BRS Topázio, sendo a variável área foliar a mais sensível. A produção total de sementes e o número de sementes total foram às variáveis mais sensíveis ao estresse salino.</p><p align="center"><strong><em>Growth and production components of colored cotton subjected to saline stress and potassium fertilization</em></strong></p><p><strong>Abstract</strong><strong>: </strong>The objective of this work was to evaluate the growth and production components of the colored cotton cv. BRS Topázio, according to the irrigation with waters of different levels of salinities and doses of potassium. The experiment was conducted in a greenhouse, using a Neolithic Regolithic Eutrophic with a non-saline sandy-loam texture in the city of Campina Grande-PB. A randomized complete block design was used in a 4 x 4 factorial design with three replications. The treatments were composed of four levels of electrical conductivity of the irrigation water (1.5, 3.0, 4.5 and 6.0 dS m<sup>-1</sup>) and four doses of potassium (50, 75, 100 and 125% of the recommendation), the dose of 100% corresponding to 150 mg K<sub>2</sub>O per kg<sup>-1</sup> of soil. The salinity of the irrigation water negatively affected the growth of the cv. BRS Topazio, the most sensitive leaf area variable. The total seed production and the total number of seeds were the variables most sensitive to saline stress.</p>
Eliminación virtual de la deficiencia de yodo en América. Trascendencia en la salud pública. Contribución de la Universidad Peruana Cayetano Heredia
Authors: Pretell Zárate Eduardo A. 
Published: October 2017

En el presente artículo se hace un breve recuento de los antecedentes y del proceso para lograr la meta de la eliminación virtual de la deficiencia de yodo en las Américas, considerado un importante problema de salud pública
PENGARUH PENGGANTIAN SEBAGIAN TANAH LIAT OLEH FLY ASH BATUBARA TERHADAP NILAI THERMAL PROPERTIES SEBAGAI UPAYA MEMETAKAN MATERIAL BATU BATA YANG RAMAH LINGKUNGAN
Authors: Forest Jedy Green , Siswanto Budi , Rahmawati Anis 
Published: October 2017

<p>Tujuan penelitian ini adalah untuk mengetahui: (1) pengaruh penggantian sebagian tanah liat oleh <em>fly ash</em> batubara terhadap nilai <em>thermal properties</em> batu bata; (2) persentase optimal penggantian sebagian tanah liat oleh <em>fly ash </em>batubara untuk mendapatkan batu bata dengan daya hambat panas maksimal; (3) nilai perbandingan <em>thermal properties</em> yang dihasilkan oleh batu bata dengan campuran <em>fly ash </em>batubara pada variasi campuran 0%, 15%, 30%, 40%, dan 50%. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode eksperimen. Karakteristik batu bata yang diuji pada penelitian ini adalah berat jenis, susut bakar, porositas, kuat tekan, dan konduktivitas termal. Benda uji yang digunakan terbuat dari tanah liat dengan campuran <em>fly ash </em>batubara dengan dimensi 23 cm x 11 cm x 5 cm. Hasil penelitian adalah sebagai berikut ini. <em>Pertama, </em>ada pengaruh penggantian sebagian tanah liat oleh <em>fly ash </em>batubara terhadap nilai <em>thermal properties</em> (F<sub>hitung</sub> 57,927 &gt; F<sub>tabel</sub> 4,67). <em>Kedua, </em>Persentase 50% merupakan persentase optimal penggantian sebagian tanah liat oleh <em>fly ash </em>batubara dengan daya hambat panas sebesar 0,201 Kcal/mhºC. <em>Ketiga, </em>nilai <em>thermal properties</em> yang dihasilkan oleh batu bata dengan campuran <em>fly ash </em>batubara pada variasi campuran 0%, 15%, 30%, 40%, dan 50% masing-masing untuk konduktivitas termal sebesar 0,362 Kcal/mhºC; 0,264 Kcal/mhºC; 0,282 Kcal/mhºC; 0,215 Kcal/mhºC; dan 0,201 Kcal/mhºC dan nilai densitas sebesar 1,35 gr/cm<sup>3</sup>; 1,18 gr/cm<sup>3</sup>; 1,14 gr/cm<sup>3</sup>; 1,02 gr/cm<sup>3</sup>; dan 0,98 gr/cm<sup>3</sup>.<strong></strong></p><p><strong> </strong></p><p><strong>Kata Kunci: </strong>batu bata, <em>fly ash </em>batubara, <em>thermal properties</em>, konduktivitas termal</p>
EVALUASI KINERJA PROGRAM STUDI PENDIDIKAN TEKNIK MESIN FKIP UNS MENGGUNAKAN METODE INTEGRATED PERFORMANCE MEASUREMENT SYSTEMS (IPMS)
Authors: Khonaah Bekti , Suharno Suharno , Harjanto Budi 
Published: October 2017

<p>Penelitian ini bertujuan untuk mengevaluasi kinerja dari Program Studi Pendidikan Teknik Mesin. Metode yang digunakan pada penelitian ini adalah (1) <em>Integrated Performance Measurement Systems</em> (<em>IPMS</em>) yang tujuan utamanya adalah merancang sistem pengukuran; (2) <em>Analytical Hierarchy Process</em> (<em>AHP</em>) yang bertujuan untuk melakukan pembobotan indikator; dan (3) <em>Objective Matrix</em> (<em>OMAX</em>) yang bertujuan untuk melakukan pengukuran kinerja. Hasil dari penelitian ini adalah sebagai berikut. <em>Pertama</em>, hasil rancangan pengukuran kinerja terdiri dari 14 indikator yang termasuk dalam 6 kriteria perspektif pengukuran kinerja. <em>Kedua</em>, tingkat kinerja pada tiap <em>Key Performance Indicators</em> (<em>KPI</em>) yang paling tinggi adalah indikator tersedia instrumen baku untuk mengukur kinerja dosen dalam perkuliahan, sedangkan kinerja yang paling rendah adalah indikator 95% lembar Berita Acara Perkuliahan (BAP). Kinerja Program Studi Pendidikan Teknik Mesin secara keseluruhan memiliki indeks kinerja sebesar 5,055, sehingga kinerja pada Program Studi Pendidikan Teknik Mesin masuk dalam kategori mengalami peningkatan kinerja. <em>Ketiga</em>, kinerja yang perlu ditingkatkan pada Program Studi Pendidikan Teknik Mesin Universitas Sebelas Maret Surakarta terdapat 8 <em>Key Performance Indicators</em> (<em>KPI</em>). Kinerja yang perlu diperbaiki pada Program Studi Pendidikan Teknik Mesin Universitas Sebelas Maret Surakarta adalah 95% lembar Berita Acara Perkuliahan (BAP) terisi.</p><p> </p><p><strong>Kata Kunci</strong>: pengukuran kinerja, <em>IPMS</em>, <em>AHP</em>, Pendidikan Teknik Mesin, <em>KPI</em>.</p>
Subiektywna i obiektywna ocena ciała studentek pielęgniarstwa Pomorskiego Uniwersytetu Medycznego w Szczecinie
Authors: Kaska Dominika 
Published: October 2017

Wstęp: W relacjach międzyludzkich ważne znaczenie ma wygląd zewnętrzny. Analiza składu ciała pozwala natomiast na jego obiektywną ocenę, która przyczynia się do realnego spojrzenia na występujące problemy.Celem pracy było ustalenie zależności pomiędzy poszczególnymi parametrami składu ciała a samooceną wyglądu wśród studentek pielęgniarstwa.Materiały i metody: Badaniami objęto grupę 210 studentek pielęgniarstwa Pomorskiego Uniwersytetu Medycznego w Szczecinie. Metodą badawczą był sondaż diagnostyczny przeprowadzony za pomocą skali oceny ciała, formularz ankiety własnego autorstwa oraz indywidualne badanie składu ciała przeprowadzone naanalizatorze Jawon Medical IOI 353.Wyniki: Większość respondentek oceniła swoją atrakcyjność seksualną na niskim bądź średnim poziomie. Na podstawie analizy składu ciała wykazano, że tylko uponad połowy respondentek masa ciała była w normie. Wskaźnik masy ciała znacznie różnił się od wyników oceniających typ budowy, wskazując, że prawie 71% przebadanych studentek odznaczało się normowagą. Wykazano występowanie wzajemnej zależności między poziomem białka a oceną kontroli wagi (p = 0,000) oraz kondycji fizycznej (p = 0,038). U 70% osób z procentową zawartością tkanki tłuszczowej powyżej normy wykazano niską samoocenę kontroli wagi oraz u 53% badanych kobiet niskie poczucie kondycji fizycznej. Zaobserwowano obecność wpływu aktywności zawodowej na ocenę ciała.Wnioski: Studentki pielęgniarstwa są średnio zadowolone z obrazu własnego ciała. Obiektywna ocena składu ciała opiera się na szczegółowych, bezstronnych irzetelnych wynikach analizy impedancji bioelektrycznej. Kobiety dbające o swoje zdrowie i utrzymujące prawidłowe parametry składu ciała charakteryzują się wysoką, subiektywną oceną ciała. Ocena własnego ciała może być zależna od wieku oraz aktywności zawodowej.
Dyskurs na temat obowiązkowych szczepień ochronnych w opinii rodziców
Authors: Kotwas Artur , Czerniak Natalia , Zabielska Paulina , Karakiewicz Beata 
Published: October 2017

Wstęp: Szczepienia są niezwykle skutecznym sposobem walki z chorobami zakaźnymi, dlatego w wielu państwach są obowiązkowe zgodnie z zaleceniami instytutów epidemiologicznych. Jak każda technologia, także i ta oprócz dużego grona zwolenników znalazła grupę krytyków, którzy negują skuteczność szczepień.Głównym celem badania było poznanie opinii rodziców na temat obowiązkowych szczepień ochronnych wieku dziecięcego.Materiały i metody: Grupę badaną stanowiło 200 rodziców w wieku 26–60 lat. Uzyskane wyniki poddano analizie statystycznej w programie PASW Statistics v.18.Wyniki: Brak poparcia dla szczepień ochronnych wieku dziecięcego wyraziło 30 (15%) osób, wśród których było 18 (13%) kobiet i 12 (19,4%) mężczyzn; 22 (22%) osoby były z woj. lubuskiego, 8 (8%) z woj. zachodniopomorskiego. Zdecydowana większość respondentów (270 osób; 85%) popierała obowiązkowe szczepienia ochronne. Bardzo ważne i ważne dla rodziców (145 osób, 72,5%) były najczęściej opinie reprezentantów zawodów medycznych (lekarz, pielęgniarka). Z poglądami ruchu antyszczepionkowego zgadzało się 49 (24,5%) osób.Wnioski: Pomimo poparcia dla ruchu antyszczepionkowego większość społeczeństwa uznaje obowiązek szczepień za ważny element profilaktyki poważnych chorób. Rodzice uważają jednak, że mają ograniczony dostęp do informacji, couniemożliwia im w pełni świadome podjęcie decyzji o zaszczepieniu dzieci.