bluuebunny/crossref_metadata_2025_split huggingface dataset:
Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells
Authors: Minami Katsuhiko , Ide Satoru , Nakazato Kako , Kaizu Kazunari , Higashi Koichi , Tamura Sachiko , Toyoda Atsushi , Takahashi Koichi , Kurokawa Ken , Maeshima Kazuhiro 
Published: October 2024

AbstractA string of nucleosomes, where genomic DNA is wrapped around histones, is organized in the cell as chromatin. Chromatin in the cell varies greatly, from euchromatin to heterochromatin, in its genome functions. It is important to understand how heterochromatin is physically different from euchromatin. However, their specific labeling methods in living cells are limited. To address this, we have developed replication-dependent histone labeling (Repli-Histo labeling) to label nucleosomes in euchromatin and heterochromatin based on DNA replication timing. We investigated local nucleosome motion in the four chromatin classes from euchromatin to heterochromatin of living human and mouse cells. We found that more euchromatic regions (earlier replicated regions) show greater nucleosome motion. Notably, the motion profile in each chromatin class persists throughout interphase. Genome chromatin is essentially replicated from regions with greater nucleosome motions, even though the replication timing program is perturbed. Our findings, combined with computational modeling, suggest that earlier replicated regions have more accessibility and local chromatin motion can be a major determinant of genome-wide replication timing.
Efficient cell-wide mapping of mitochondria in electron microscopic volumes using webKnossos
Authors: Jiang Yi , Wang Haoyu , Boergens Kevin , Rzepka Norman , Wang Fangfang , Hua Yunfeng 
Published: October 2024

SUMMARYRecent technical advances in volume electron microscopy (vEM) and artificial intelligence-assisted image processing have facilitated high throughput quantifications of cellular structures, such as mitochondria that are ubiquitous and morphologically diversified. A still often overlooked computational challenge is to assign cell identity to numerous mitochondrial instances, for which both mitochondrial and cell membrane contouring used to be required. Here, we present a vEM reconstruction procedure (called mito-SegEM) that utilizes virtual path-based annotation to assign automatically segmented mitochondrial instances at the cellular scale, therefore bypassing the requirement of membrane contouring. The embedded toolset in webKnossos (an open-source online annotation platform) is optimized for fast annotation, visualization, and proofreading of cellular organelle networks. We demonstrate broad applications of mito-SegEM on volumetric datasets from various tissues, including the brain, intestine, and testis, to achieve an accurate and efficient reconstruction of mitochondria in a use-dependent fashion.
Cooperative motility emerges in crowds of T cells but not neutrophils
Authors: Wortel Inge MN , Postat Jérémy , Mihaylova Mihaela , Merino Mauricio , Bhagrath Aanya , Harris Maryl , Wouters Lin , Wiebke Lucas , Parisi Daniel R , Mandl Judith N , Textor Johannes 
Published: October 2024

AbstractT cells are among the most motile immune cells in the body, and their migration into and within tissues is key to their function. Remarkably, T cells can maintain their motility even in highly crowded environments like the densely packed T cell areas of lymphoid organs, but how they do so remains incompletely understood. Here, we use microfluidic devices andin silicomodels to study T cells from a crowd dynamics perspective, focusing on a hallmark scenario that has proven instrumental in characterizing other crowded systems such as pedestrians and ants: single-lane traffic. Unexpectedly, T cells in narrow, straight microchannels synchronize their speeds and form stable, motile trains. We show that this behavior can be explained by a preference of T cells to maintain contact with each other after collisions, and an ability of faster T cells to “push” slower ones. We demonstrate that this behavior does not extend to all immune cells; neutrophils in the same settings slow down with increasing cell density. Cooperative motion may benefit T cell motility in difficult and crowded tissue environments, ultimately preventing jams that impair motion in other crowded systems.
A multi-attribute group decision-making framework for site selection of waste-to-energy project considering public participation
Authors: Ma Shengbin , Li Zhongfu , Zhang Jingqi 
Published: October 2024

PurposeThe waste-to-energy (WtE) project plays a significant role in the sustainable development of urban environments. However, the inherent “Not in my backyard” (NIMBY) effect presents substantial challenges to site selection decisions. While effective public participation is recognized as a potential solution, research on incorporating it into site selection decision-making frameworks remains limited. This paper aims to establish a multi-attribute group decision-making framework for WtE project site selection that considers public participation to enhance public satisfaction and ensure project success.Design/methodology/approachFirstly, based on consideration of public demand, a WtE project site selection decision indicator system was constructed from five dimensions: natural, economic, social, environmental and other supporting conditions. Next, the Combination Ordered Weighted Averaging (C-OWA) operator and game theory were applied to integrate the indicator weight preferences of experts and the public. Additionally, an interactive, dynamic decision-making mechanism was established to address the heterogeneity among decision-making groups and determine decision-maker weights. Finally, in an intuitive fuzzy environment, an “acronym in Portuguese of interactive and multi-criteria decision-making” (TODIM) method was used to aggregate decision information and evaluate the pros and cons of different options.FindingsThis study develops a four-stage multi-attribute group decision-making framework that incorporates public participation and has been successfully applied in a case study. The results demonstrate that the framework effectively handles complex decision-making scenarios involving public participation and ranks potential WtE project sites. It can promote the integration of expert and public decision-making preferences in the site selection of WtE projects to improve the effectiveness of decision-making. In addition, sensitivity and comparative analyses confirm the framework’s feasibility and scientificity.Originality/valueThis paper provides a new research perspective for the WtE project site selection decision-making, which is beneficial for public participation to play a positive role in decision-making. It also offers a valuable reference for managers seeking to effectively implement public participation mechanisms.
Present bias and its influence on financial behaviours amongst Indians
Authors: Maji Sumit Kumar , Prasad Sourav 
Published: October 2024

PurposePresent bias (PB) is a cognitive bias that stimulates the individual decision-maker to favour the present reward even over the higher reward in the future to avoid the uncertainty attached to the reward in an uncertain future. The article attempts to examine the prevalence of PB amongst Indians and the effect of such bias on savings and borrowings.Design/methodology/approachSecondary data on 47,132 respondents from the Financial Inclusion Insights, 2017 database was used in the study. The theory of self-control, which is captured by the widely accepted hyperbolic discounting model, was used to explore the presence of PB. Suitable statistical techniques and the binary probit regression model were employed to attain the objectives of the study.FindingsThe prevalence of PB was found amongst 8.2% of the sample respondents. The outcome of the study endorses the view of previous researchers that present-biased people tend to save less and borrow more.Originality/valueAlthough the exploration of the role of various cognitive biases on financial behaviour is gaining momentum in recent times, there is a dearth of studies exploring the prevalence of PB and its implication towards financial behaviour, especially in the context of the emerging economy of India. The study makes an original contribution in this regard by using a very rich dataset of 47,132 individuals in the Indian context for the first time.
Management accounting change in merger and acquisitions: a multiple-case study
Authors: Mariani Andrea , Cifalinò Antonella , Lisi Irene Eleonora , Rizzo Marco Giovanni 
Published: October 2024

Purpose
Despite the literature highlighting the relevance of mergers and acquisitions (M&As) as strategic options for organizations’ evolution, such events maintain a high failure rate. All stages of M&As generate considerable stress on management accounting systems (MASs) and related actors. This study aims to investigate management accounting change (MAC) throughout M&As to expand knowledge on the technical side of these changes. A deeper understanding of these changes and their relationship to the implementing agents could illuminate the causes of M&A success and failure.

Design/methodology/approach
The study uses an in-depth, qualitative case study analysis of two companies that completed an M&A. The MAC process was investigated based on Sulaiman and Mitchell’s (2005) typology. The authors collected information from internal documents, interviews, external reports and public information.

Findings
The findings indicate that MAC in M&As represents a comprehensive change that goes beyond the modifications outlined in Sulaiman and Mitchell’s (2005) original framework; the post-deal integration period can be broken down into early and full sub-phases; and the success of the MAC process rests on the different roles played by various change agents.

Originality/value
To the best of the authors’ knowledge, this study is among the first to apply and deepen a MAC framework focused on technical changes to MASs in the context of M&As. To date, the literature on M&A has mainly focused on behavioral or organizational changes while neglecting the technical dimension. In addition, by considering all the stakeholders of MASs, this study’s analyses expose the role of change agents who are not generally considered in the accounting literature.
How psychological perceptions and family dynamics shape necessity- and opportunity-based female entrepreneurship: the role of gender equality
Authors: Deng Wei , Liang Qiaozhuan , Wang Wei , Zhang Yue 
Published: October 2024

Purpose
This paper aims to explore how psychological perceptions and family situations drive women into necessity- or opportunity-based female entrepreneurship (NBFE or OBFE) and the moderating role of gender equality.

Design/methodology/approach
This study adopts multilevel logistic regression analysis to examine relationships based on a sample of 6,843 women across eight developing countries drawn from the Global Entrepreneurship Monitor (GEM).

Findings
The findings suggest that capability and opportunity perceptions positively affect NBFE and OBFE. Family responsibility burden positively affects NBFE and has a U-shaped relationship with OBFE. Household income negatively affects NBFE but positively affects OBFE. Gender equality weakens the U-shaped relationship between family responsibility burden and OBFE but strengthens the positive relationship between capability perception and NBFE and between opportunity perception and NBFE.

Research limitations/implications
The study highlights the need for targeted policies and support that consider the distinct antecedents and mechanisms of NBFE and OBFE, as well as the importance of promoting gender equality and entrepreneurial education to empower women in their entrepreneurial endeavors. A limitation of this study is the reliance on older data from the GEM, which may not fully capture the current dynamics of developing societies. While the study provides valuable insights, future research should incorporate more recent data to enhance the applicability of the results.

Originality/value
This study deepens the understanding of antecedents of NBFE and OBFE, breaking through the existing literature that neglects the heterogeneity of female entrepreneurship (FE).
Structure and functions of talking book mobile applications: a comparative study of Google Play Books, Audible, LibriVox, Storytel and Loyal Books
Authors: Bhardwaj Raj Kumar , K.R. Abhilash 
Published: October 2024

PurposeTalking book mobile applications have introduced the concept of reading through listening. Though conventional reading methods are preferable, talking book mobile applications have the advantage that they treat every user equally. The purpose of this paper is to compare the five popular talking book mobile applications namely Google Play Books, Audible, LibriVox, Storytel and Loyal Books.Design/methodology/approachThis research compares and evaluates features and functionalities of five different talking book mobile applications using a checklist method. A structured checklist is prepared to compare the five popular talking book mobile applications comprising 261 dichotomous questions divided into 13 categories.FindingsAfter evaluating the features, an attempt was made to rate the selected applications. According to the evaluation, Audible application performed better than others. This study about the features and functions of talking book mobile applications considered a total number of 261 features from the selected five mobile applications. Audible is ranked first with 182 (69.7%) features and is rated “Above average”; Storytel (68.2%) is second with 178 features, also rated “Above average”; Google Play Books ranked third with 161 (61.7%) features, rated “Average”; LibriVox ranked fourth with 151 (57.9%) features and is rated “Below average”. Fifth is Loyal Books with 130 (49.8%) features, rated “Below average”.Research limitations/implicationsThe study covers only five talking book mobile applications. The checklist used in the study is generic covering limited features. Further, the perceptions of users were also not included while comparing the talking book mobile applications. The study does not comprehend whether the talking book mobile applications fulfil the information needs of the users.Practical implicationsUsers can use the findings of the study in choosing the suitable talking book mobile application suitable to their requirements. Instructors of information literacy programmes can use the checklist to train the users in using talking book mobile applications that can accelerate the usage of these mobile applications.Originality/valueThe study identifies the features that should be available in a model talking book mobile application. Features of the talking book mobile applications were evaluated after preparing the detailed checklist. Features were divided into 13 different categories. The checklist used in the study is original and the first of its kind. The findings of the study can be used by developers of talking book mobile applications to improve their functionalities.
Shifting trait coordination along a soil‐moisture‐nutrient gradient in tropical forests
Authors: Boisseaux Marion , Nemetschek Daniela , Baraloto Christopher , Burban Benoit , Casado‐Garcia Angela , Cazal Jocelyn , Clément Jeanne , Derroire Géraldine , Fortunel Claire , Goret Jean‐Yves , Heras Jonathan , Jaouen Gaelle , Maréchaux Isabelle , Scoffoni Christine , Vieilledent Ghislain , Vleminckx Jason , Coste Sabrina , Schimann Heidy , Stahl Clément 
Published: October 2024

Abstract

Soil nutrients and water availability are strong drivers of tropical tree species distribution across scales. However, the physiological mechanisms underlying environmental filtering along these gradients remain incompletely understood. Previous studies mostly focused on univariate variation in structural traits, but a more integrative approach combining multiple physiological traits is needed to fully portray species functional strategies.

We measured nine leaf functional traits related to trees' resource capture and hydraulic strategies for 552 individuals belonging to 21 tropical tree species across an environmental gradient in Amazonian forests. Our sampling included generalist and specialist species from terra firme (TF) and seasonally flooded (SF) forests. We tested the influence of the topographic wetness index, a proxy for soil moisture and nutrient gradients, on each trait separately and on the trait integration through multivariate indices computed from the eigenvalues of a principal component analysis on the traits of the species. Finally, we evaluated intraspecific trait variability (ITV) for generalists and specialists by calculating the coefficient of variation for each trait.

Results showed that (1) the environment had a greater influence on trait syndromes than single trait variation. Moreover, (2) SF specialist species expressed a stronger leaf trait coordination than TF specialist species. Furthermore, (3) the ability of generalist species to occupy a broader range of environments was not reflected by a larger ITV than specialist species but by the capacity to change trait coordination across environments.

Our work highlights the need to investigate functional strategies as multidimensional syndromes in physiological trait space to fully understand and predict species distribution along environmental gradients.

Read the free Plain Language Summary for this article on the Journal blog.
Challenges in the Consumer‐Side of the Energy Transition
Authors: La Nauze Andrea , Menezes Flavio 
Published: October 2024

AbstractThe decarbonisation of the Australian economy relies on the transition of the electricity grid from fossil fuel to renewable sources. In this paper, we briefly summarise the logic behind the design of the National Electricity Market, the market servicing 88% of the Australian population. We then explore the challenges facing the National Electricity Market during its transition and emphasise key proposals aimed at reforming the consumer, or demand‐side, of the market. We highlight four challenges ‐ whether consumers will be active, whether retail markets can deliver contracts that facilitate efficient transition, whether the wholesale market will operate effectively and whether regulatory barriers can be quickly addressed.
Food insecurity and health conditions in the Australian adult population: A nationally representative analysis
Authors: Fry Jane M. , Temple Jeromey B. , Williams Ruth 
Published: October 2024

AbstractAimThis study aimed to identify key health condition correlates of food insecurity in Australia using nationally representative data.MethodsThis cross‐sectional study used data from a large, nationally representative Australian survey that included questions on the dynamics of families and households, income, wealth, welfare, labour market activity (including unemployment and joblessness), life satisfaction and wellbeing. Binary logistic regression models of eight items of food insecurity measured the association between 17 health conditions and food insecurity while controlling for various demographic and socioeconomic variables. A zero‐inflated negative binomial model identified correlates of the number of food insecurity problems.ResultsPrevalence of food insecurity ranged from 3% to 9% depending on the measure analysed. Individuals experiencing blackouts, fits or loss of consciousness were 2–6 times more likely to report food insecurity than other individuals. When including control variables and incorporating other health conditions, several conditions significantly increased probability of any food insecurity: sight problems; blackouts, fits or loss of consciousness; difficulty gripping things; nervous conditions; mental illness; and chronic or recurring pain.ConclusionsDetailed information on how health conditions are associated with different types of food insecurity was generated using population‐representative data, 17 sets of health conditions, and eight measures of food insecurity. Understanding connections between food insecurity and health conditions allows public health professionals to create effective, targeted and holistic interventions.
Systematic review of extrahepatic hepatic artery pseudoaneurysm following adult liver transplantation: Risk factors and treatment modalities
Authors: Pereira Ryan , Pearch Benjamin J , Pavilion Gilbert , Rajkomar Kheman 
Published: October 2024

SummaryHepatic artery pseudoaneurysm (HAP) is a rare vascular complication following liver transplantation (LTx) with treatment choice frequently driven by institutional experience. Approximately, 10% of hepatic grafts are lost from this complication, requiring re‐transplantation and placing further demand on the already present organ shortage. Secondly, patients with HAP can present with catastrophic bleeding, with reported mortality of up to 78%. We aim to identify risk factors associated with HAP and assess the survival benefit of different treatment modalities used (endovascular and open surgical techniques). Early detection may facilitate semi‐elective management of this condition. A systematic search was performed in PubMed, Medline and Embase up to 1 October 2023. Case series with ≥5 patients focusing on adult patients who developed extrahepatic pseudoaneurysm following LTx were included. A total of 11 studies were pooled, comprising of 118 patients with survival data available in 61 patients. The most common presentation was haemorrhagic shock or luminal haemorrhage (75.5%). Bile leak was documented in 66.7% (28/42), 15.2% (18/118) associated foregut pathologies and 28.6% (14/49) of microbiology cultures grew a fungal organism. Flow preserving strategies (stenting, revascularization) trended towards better survival at 120 months compared to non‐flow preserving strategies (embolization, HAL); however, this was not statistically significant following log rank (Mantel–Cox) analysis (P 0.169). Any patient following LTx presenting with haemorrhagic shock or luminal bleeding needs HAP excluded urgently. HAP management is complex, requiring careful consideration of patient specific presentation, anatomic factors and associated pathologies.
Stereotactic body radiotherapy alone versus stereotactic body radiotherapy after incomplete transarterial therapy for hepatocellular carcinoma
Authors: Song Youngju , Jung Jinhong , Park Jin‐hong , Kim So Yeon , Choi Jonggi , Lee Danbi , Shim Ju Hyun , Kim Kang Mo , Lim Young‐Suk , Lee Han Chu , Yoon Sang Min 
Published: October 2024

AbstractIntroductionWe investigated the clinical outcomes of stereotactic body radiation therapy (SBRT) alone versus SBRT after incomplete transarterial chemoembolization (TACE) for a single recurrent hepatocellular carcinoma (HCC) smaller than 5 cm.MethodsWe retrospectively reviewed the medical records of patients who underwent SBRT for a single recurrent HCC ≤5 cm, without vascular invasion or extrahepatic metastasis. Patients were divided into the SBRT‐alone group and the TACE‐SBRT group. The primary outcome was the local control (LC) rate, and secondary outcomes were survivals and treatment‐related toxicities. We additionally conducted a propensity score matching (PSM) analysis.ResultsA total of 477 patients were available for analysis. Among them, 54 patients received SBRT without prior treatment to the target lesion (SBRT‐alone group), whereas 423 patients received SBRT for viable HCC after TACE (TACE‐SBRT group). The 3‐year LC rates did not differ between the two groups (SBRT‐alone group, 88.6% vs. TACE‐SBRT group, 89.6%, P = 0.918). The 3‐year rates of overall survival, out‐of‐field intrahepatic recurrence‐free survival and recurrence‐free survival were also not significantly different (P = 0.479, 0.290 and 0.273, respectively). Even after PSM, LC and survival rates at 3 years were not significantly different.ConclusionSBRT alone demonstrated comparable local control and survival outcomes to SBRT following incomplete TACE. SBRT alone may be considered an alternative treatment option for a single recurrent HCC smaller than 5 cm when curative treatments or TACE are not feasible.