bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organisation and management of multi-professional care for cancer patients at end-of-life: state-of-the-art from a survey to community and hospital-based professionals
Authors: Zuccarino Sara , Gioia Angela , Quattrone Filippo , Nuti Sabina , Emdin Michele , Ferrè Francesca 
Published: October 2024

AbstractProviding timely and satisficing End-of-Life care (EOLC) is a priority for healthcare systems since aging population and chronic diseases are boosting the global demand for care at end-of-life (EOL). In OECD countries the access to EOLC is insufficient. In Italy, the average rate of cancer patients assisted by the palliative care (PC) network at EOL was 28% in 2021, with high variability in the country. Among the Italian regions offering the best coverages, Tuscany has a rate of about 40%, but intraregional variation is marked as well. The study aims to explore the delivery of EOLC to adult cancer patients in public facilities in the Tuscany region through survey data collection among professionals. Two online surveys were delivered to Directors of community-based PC Functional-Units (FUs) and Directors of hospital-based medical-oncology units. All FU Directors responded to the survey (n = 14), and a response rate of 96% was achieved from hospital-unit Directors (n = 27). The results highlight the availability of numerous dedicated services, but reveal heterogeneity among and within organisations, including variations in the professionals involved, pathways, and tools adopted. Care continuity is supported by institutionalized collaboration between hospital and community settings, but hindered by fragmented care processes and heterogeneous transition pathways. Late referral to PC is perceived as a major constraint to EOLC. Developing structured pathways for patient transition to end-stage PC is crucial, and practices/processes should be uniformly implemented to ensure equity. Multi-professional care should be facilitated through tailored supporting tools. Both hospital-unit and FU Directors suggest developing shared pathways between organisations/professionals (82% and 80% respectively) and digital information sharing (61% and 80% respectively). Hospital and community-based professionals have similar perceptions about the concerns and challenges to EOLC provision in the region, but community-based professionals are more sensitive to the importance of improving communication on PC to the public and early discussing EOLC with caregivers. This finding suggests the need of enhancing hospital personnel’s awareness about these issues. Professional training and the capacity to assess patients’ needs and preferences should be improved. The identified needs can inform future research and interventions to improve the quality and outcomes of EOLC for cancer patients.
Challenges in performing a structured follow-up in Swedish nursing home residents after stroke: a pilot feasibility study
Authors: Lindgren Ingrid , Rejnö Åsa , Netterheim Anna , Midlöv Patrik , Ervander Cecilia , Pessah-Rasmussen Hélène 
Published: October 2024

AbstractMultidisciplinary team-based follow-ups are recommended for all stroke patients in Sweden including those discharged to nursing homes. We aimed to explore the feasibility of a structured follow-up with the Post Stroke Checklist (PSC) in nursing home residents, and to map stroke related problems and planned interventions. Due to a complex recruitment process and low recruitment rate, the study protocol was adapted to an explorative design. Nine health professionals and five nursing home residents participated. The health professionals were generally satisfied with the PSC. Many stroke related problems were identified, and several inexpensive ongoing or planned interventions were considered. However, several obstacles for performing a routine structured stroke follow-up were identified, such as lack of coordination between different stakeholders, fear of increased paperwork and lack of referral options for some of the suggested interventions, indicating that there is a need to build up a suitable organization able to take action for the identified problems. Various hinders performing the study itself were also identified. Difficulties in recruiting physically and mentally frail participants in studies might lead to an inadequate basis for decision-making, hindering people with extensive disabilities to receive scientifically based interventions.
Deathscape, materiality and memorialisation: Arandora Star remembrance in Scotland
Authors: Colpi Terri 
Published: October 2024

AbstractThis article progresses Second World War historiography of ‘enemy alien’ internment, especially of the SS Arandora Star, sunk in 1940 with a high loss of Italian civilian lives. Employing a new paradigm, that of the deathscape, defined as a topography of death and the practices that surround it, this investigation recontextualises Arandora Star remembrance in Scotland. Ambiguous loss, complicated grieving, disenfranchisements in mourning and absences in multiple layers of the deathscape form overarching themes that are explored in parallel to emotional-affective memory. The previously neglected study of individual memorialisation, both private and ‘official’, provides an important primary source in the fragmented materiality of the deathscape, allowing fresh insight on both cultural manifestations and political context. As the material and cultural apex of the deathscape, the Italian Cloister Garden and Arandora Star Memorial in Glasgow, created by Archbishop Mario Conti in 2011, are evaluated through the lenses of leadership, identity and heritage activism.
Raising the Arandora Star: history and afterlife of the Second World War sinking
Authors: Colpi Terri 
Published: October 2024

AbstractSince the sinking of SS Arandora Star 84 years ago, the memory of this tragic wartime incident has been strongly held and developed within the British Italian community, moving through several phases, from oblivion to recognition and commemoration to a more recent growing awareness in a wider mnemonic community of interest. The aim of this special issue is threefold: to raise further the profile of the Arandora Star; to consolidate and secure the uncertain historical foundations of the event; and to advance the historiography by introducing new facts and perspectives and uncovering previously hidden or unknown aspects both of the past and the continuing afterlife. The six articles presented move logically through the history and stages of memory evolution and its manifestation – internment and deportation, the sinking itself, material, cultural and political aspects of the deathscape, oral histories, the multimedia ‘archive’, with finally, an embarkation listing to plug a serious knowledge gap.
The theological foundations of Muslim modernism and traditionalism in South Asia
Authors: Tareen SherAli 
Published: October 2024

AbstractThis article examines the theological and hermeneutical foundations and fault lines of Muslim modernism and traditionalism in South Asia. It does so through a close reading of a massively consequential but thus far unstudied debate on the normative sources and interpretive parameters of religion in colonial modernity between the scholars Sayyid Ahmad Khan (d. 1898) and Muhammad Qasim Nanautvi (d. 1877), founders of arguably the most prominent bastions of modernism and traditionalism in Muslim South Asia: the Aligarh Muslim University and the Deoband Madrasa, both established in the late nineteenth century.
Muslim feminism as Islamic modernism: Women’s activism in India between the Quran and the Constitution
Authors: Jones Justin 
Published: October 2024

AbstractThe last 15–20 years have seen the emergence of a new trajectory of ‘Muslim feminism’ in India which has grounded Muslim women’s rights discourse both in the direct interpretation of Islamic scriptures and also in principles derived from the Indian Constitution. Examining two prominent Muslim women’s organizations—the All India Muslim Women’s Personal Law Board and the Bharatiya Muslim Mahila Andolan—this article examines how this form of Muslim feminism has become a central repository of Islamic modernist thought in India in light of its perceived failure in some other sections of Muslim public life. Based on writings and educational materials produced by these organizations, this article discusses their methods of harnessing the teachings of the Quran, their application of ‘Islamic feminist’ methodology to interpret Islamic family laws, their identification of equivalence between Islamic and constitutional values, and their attempts to engage the state in their efforts to promote the modernization of Muslim Personal Law.
Partial recovery and weak consistency in the non-uniform hypergraph stochastic block model
Authors: Dumitriu Ioana , Wang Hai-Xiao , Zhu Yizhe 
Published: October 2024

AbstractWe consider the community detection problem in sparse random hypergraphs under the non-uniform hypergraph stochastic block model (HSBM), a general model of random networks with community structure and higher-order interactions. When the random hypergraph has bounded expected degrees, we provide a spectral algorithm that outputs a partition with at least a $\gamma$ fraction of the vertices classified correctly, where $\gamma \in (0.5,1)$ depends on the signal-to-noise ratio (SNR) of the model. When the SNR grows slowly as the number of vertices goes to infinity, our algorithm achieves weak consistency, which improves the previous results in Ghoshdastidar and Dukkipati ((2017) Ann. Stat.45(1) 289–315.) for non-uniform HSBMs.Our spectral algorithm consists of three major steps: (1) Hyperedge selection: select hyperedges of certain sizes to provide the maximal signal-to-noise ratio for the induced sub-hypergraph; (2) Spectral partition: construct a regularised adjacency matrix and obtain an approximate partition based on singular vectors; (3) Correction and merging: incorporate the hyperedge information from adjacency tensors to upgrade the error rate guarantee. The theoretical analysis of our algorithm relies on the concentration and regularisation of the adjacency matrix for sparse non-uniform random hypergraphs, which can be of independent interest.
Aberrant right subclavian artery intervention can provide relief of dysphagia
Authors: Medina Cathlyn K. , Kucera John A. , Aykut Berk , Prabhu Neel K. , Kang Lillian , Lim Hoe K. , Beckerman Ziv , Overbey Douglas M. , Turek Joseph W. 
Published: October 2024

AbstractBackground:An aberrant right subclavian artery represents the most common aortic arch vascular anomaly. Conventional wisdom states that these anomalies do not result in dysphagia, but rather serve as “red herrings”. Clearly, in the vast majority of cases, this holds true. Nonetheless, one should never say never.Methods:Herein, we present a cohort of four children with debilitating dysphagia resulting from an aberrant right subclavian artery. Subclavian reimplantation via a right posterolateral thoracotomy was performed successfully in all cases.Results:Dysphagia resolved postoperatively, and all patients were able to advance to a normal diet. They were able to gain appropriate weight postoperatively and continue to do well at most recent clinical follow-up.Conclusions:This case series suggests that aberrant right subclavian artery anatomy should be considered a potential aetiology of dysphagia, albeit rarely. Surgical intervention for select patients can provide dramatic resolution of symptoms.
Ultra-high brightness Micro-LEDs with wafer-scale uniform GaN-on-silicon epilayers
Authors: Wu Haifeng , Lin Xiao , Shuai Qin , Zhu Youliang , Fu Yi , Liao Xiaoqin , Wang Yazhou , Wang Yizhe , Cheng Chaowei , Liu Yong , Sun Lei , Luo Xinyi , Zhu Xiaoli , Wang Liancheng , Li Ziwei , Wang Xiao , Li Dong , Pan Anlian 
Published: October 2024

AbstractOwing to high pixel density and brightness, gallium nitride (GaN) based micro-light-emitting diodes (Micro-LEDs) are considered revolutionary display technology and have important application prospects in the fields of micro-display and virtual display. However, Micro-LEDs with pixel sizes smaller than 10 μm still encounter technical challenges such as sidewall damage and limited light extraction efficiency, resulting in reduced luminous efficiency and severe brightness non-uniformity. Here, we reported high-brightness green Micro-displays with a 5 μm pixel utilizing high-quality GaN-on-Si epilayers. Four-inch wafer-scale uniform green GaN epilayer is first grown on silicon substrate, which possesses a low dislocation density of 5.25 × 108 cm−2, small wafer bowing of 16.7 μm, and high wavelength uniformity (standard deviation STDEV < 1 nm), scalable to 6-inch sizes. Based on the high-quality GaN epilayers, green Micro-LEDs with 5 μm pixel sizes are designed with vertical non-alignment bonding technology. An atomic sidewall passivation method combined with wet treatment successfully addressed the Micro-LED sidewall damages and steadily produced nano-scale surface textures on the pixel top, which unlocked the internal quantum efficiency of the high-quality green GaN-on-Si epi-wafer. Ultra-high brightness exceeding 107 cd/m2 (nits) is thus achieved in the green Micro-LEDs, marking the highest reported results. Furthermore, integration of Micro-LEDs with Si-based CMOS circuits enables the realization of green Micro-LED displays with resolution up to 1080 × 780, realizing high-definition playback of movies and images. This work lays the foundation for the mass production of high-brightness Micro-LED displays on large-size GaN-on-Si epi-wafers.
The clinical evolution of patients with idiopathic spinal cord herniation: a case series
Authors: Flageol Stéphanie , Carrondo-Cottin Sylvine , Turmel André , Côté Isabelle , Paquet Jérôme 
Published: October 2024

Abstract
Study design
Retrospective case series of 48 patients.

Objectives
This study’s primary objective was to provide a clinical description of a group of individuals with a working diagnosis of idiopathic spinal cord herniation (ISCH). The secondary objectives were to appreciate the natural history of these patients and describe their clinical evolution with conservative or surgical management.

Setting
The study was carried out at l’Hôpital de l’Enfant-Jésus, CHU de Québec (Québec, Canada), a tertiary care university hospital.

Methods
This case series study is based on routinely collected data. Forty-eight (48) cases were identified as having an ISCH on MR imaging, between 2009 and 2019. Their medical files have been searched retrospectively. Patient characteristics were described according to their asymptomatic or symptomatic status.

Results
The mean age of patients at the time of diagnosis was 52.5 years. Most of the patients identified were asymptomatic (69%) and followed clinically. The main neurologic presentation for the symptomatic group was Brown-Séquard-like syndrome. 20% of the symptomatic patients were rapidly treated surgically after consultation with the neurosurgeon. The mean follow-up duration was 56 months for asymptomatic patients and 51 months for symptomatic patients. Most of our patients (41 out of 45) were considered stable or unchanged at follow-up. There was no neurological progression in all asymptomatic patients.

Conclusions
Our study shows that ISCH and its variants are not always symptomatic and may be a fortuitous finding. As the natural history may be non-progressive, it is probably appropriate to treat some cases expectantly.
CircMETTL3-156aa reshapes the glycolytic metabolism of macrophages to promote M1 polarization and induce cytokine storms in sHLH
Authors: Xie Longlong , Deng Xiangying , Li Xiao , Li Xun , Wang Xiangyu , Yan Haipeng , Zhao Lin , Yang Dan , Luo Ting , Yang Yufan , Xiao Zhenghui , Lu Xiulan 
Published: October 2024

AbstractPersistent macrophage activation and cytokine storms are critical causes for the rapid disease progression and high mortality rate of Secondary Hemophagocytic lymphohistiocytosis (sHLH). Identification of key regulatory factors that govern the activation of macrophages is vital. Plasma exosomal circular RNAs (circRNAs) are considered important biomarkers and potential therapeutic targets for various diseases, however, their function in sHLH is still unclear. In this study, we demonstrated for the first time that circMETTL3, derived from METTL3, is upregulated in sHLH patient plasma exosomes, which may plays an important role in the diagnosis of sHLH. Significantly, we also revealed that a novel peptide encoded by circMETTL3, METTL3-156aa, is an inducer of M1 macrophage polarization, which is responsible for the development of cytokine storms during sHLH. We then identified that METTL3-156aa binding with lactate dehydrogenase A (LDHA) and promotes M1 macrophage polarization by enhancing macrophage glycolysis. Additionally, the glycolysis metabolite lactate upregulates the cleavage factor SRSF10 expression by lactylation. This results in increased splicing of the pre-METTL3 mRNA, leading to an enchance in the production of cirMETTL3. Therefore, our results suggest that the circMETTL3/METTL3-156aa/LDHA/Lactate/SRSF10 axis forms a positive feedback loop and may be a novel therapeutic target for the treatment of sHLH.
Adaptive optics scanning laser ophthalmoscopy in a heterogenous cohort with Stargardt disease
Authors: Shah Mital , Downes Susan M. , Smithson Hannah E. , Young Laura K. 
Published: October 2024

AbstractImage based cell-specific biomarkers will play an important role in monitoring treatment outcomes of novel therapies in patients with Stargardt (STGD1) disease and may provide information on the exact mechanism of retinal degeneration. This study reports retinal image features from conventional clinical imaging and from corresponding high-resolution imaging with a confocal adaptive optics scanning laser ophthalmoscope (AOSLO) in a heterogenous cohort of patients with Stargardt (STGD1) disease. This is a prospective observational study in which 16 participants with clinically and molecularly confirmed STGD1, and 7 healthy controls underwent clinical assessment and confocal AOSLO imaging. Clinical assessment included short-wavelength and near-infrared fundus autofluorescence, spectral-domain optical coherence tomography, and macular microperimetry. AOSLO images were acquired over a range of retinal eccentricities (0°–20°) and mapped to areas of interest from the clinical images. A regular photoreceptor mosaic was identified in areas of normal or near normal retinal structure on clinical images. Where clinical imaging indicated areas of retinal degeneration, the photoreceptor mosaic was disorganised and lacked unambiguous cones. Discrete hyper-reflective foci were identified in 9 participants with STGD1 within areas of retinal degeneration. A continuous RPE cell mosaic at the fovea was identified in one participant with an optical gap phenotype. The clinical heterogeneity observed in STGD1 is reflected in the findings on confocal AOSLO imaging.
Analyse phénoméno-structurale de l’acte et du rapport au corps dans le suivi psychologique d’une adolescente
Authors: Emsallem Nicolas 
Published: October 2024

Nos rencontres cliniques, dans un service de pédopsychiatrie, avec des adolescents en grandes difficultés psychologiques, nous ont amené à considérer la place essentielle des manifestations expressives de l’acte et du rapport au corps dans le processus de l’adolescence. Nous avons fréquemment observé comment les manifestations corporelles et agies, qui se déploient avec force et intensité à cet âge, se mettent au service d’une réalité complexe et souvent indicible, tant à un niveau personnel qu’au sein d’implications relationnelles, voire transgénérationnelles. L’analyse des valeurs structurales, expressives et communicatives de ces manifestations, témoigne bien souvent d’une « lutte psychique » (Winnicott, 1982, Wawrzyniak & Schmit, 2008) pour maintenir une continuité et une cohérence au sein de l’organisation de la personnalité et du système relationnel, et par là, une continuité du sentiment d’existence. Nous proposons une illustration à travers l’analyse détaillée d’entretiens cliniques et des épreuves de Rorschach et du Village d’une adolescente. Une place primordiale est accordée aux modalités perceptives et représentatives des figures humaines, de l’espace et du temps vécus, aux modes d’intégration des facteurs dynamiques ainsi qu’aux registres d’expression et de réalisation de l’intentionnalité. Nous précisons comment les sentiments d’existence, de la réalité et d’appartenance tiennent une place centrale dans le processus de quête identitaire. Les caractéristiques dégagées sont replacées dans une compréhension unitaire de l’organisation de la personnalité et du contexte relationnel de l’adolescente ; s’y tracent des pistes essentielles pour son accompagne ment psychologique.
Cultural transfer in the French Enlightenment
Authors: van Tilburg Marja 
Published: October 2024

Abstract
Over the last decade, scholars of the Enlightenment have shown how cultural critics all over Europe –
fashioning themselves as philosophes – took inspiration from non-Western cultures. Articulating their
criticism of contemporary European society, they drew comparisons with seemingly better functioning societies in other parts
of the world. How they selected and processed relevant information, however, has not been given due attention. How this
information was subsequently used in Enlightenment thinking has hardly been analysed – as if philosophes only
adopted ideas instead of examining and revising them in the process. To point out this last aspect of Enlightenment culture,
this article discusses two important late eighteenth century texts. The first is the report of the French explorer
Bougainville about his sojourn on Tahiti (1771). This author renders extraordinary sexual mores intelligible by referring to
the Enlightenment concept of “natural man.” The second is the commentary of the French philosophe Diderot,
who used the above report to develop an alternative to French sexual mores (several versions, 1771–1784). Together, these two
texts offer examples of Enlightenment cultural transfer: the explorer describing Tahitian culture in a way which inspires the
cultural critic to formulate new sexual mores and to discuss the feasibility of their implementation in contemporary
Europe.
Cultural transfer as a performative act in Mary Wollstonecraft’s Letters written during a short residence in
Sweden, Norway and Denmark (1796)
Authors: Broomans Petra 
Published: October 2024

Abstract
Mary Wollstonecraft (1759–1797) is well known for her feminist pamphlet A Vindication of the Rights
of Women (1792). Wollstonecraft was also an experienced traveller. She travelled to Portugal, and she lived and
worked in Ireland, London and Paris. Her travel account about her stay in Scandinavia, Letters written during a short
residence in Sweden, Norway and Denmark, was published in 1796.
Her life and works have fascinated many artists, writers and scholars over time, starting with her husband,
the philosopher William Godwin (1756–1836), who published the Memoirs of the Author of ‘The Rights of Woman’
in 1798. More recently, Nigel Leask (2019), Anca-Raluca Radu (2020), Elizabeth Zold (2023), Michael Meyer (2023) and Luisa Simonutti (2024), amongst
others, discussed the Letters in different contexts. I will begin this chapter by giving a brief overview of
the outlines in this remarkable renaissance of ‘Mary Wollstonecraft studies’.
I will continue by positioning Wollstonecraft’s Letters within the genre of travel
writing. In my analysis I will focus on two concepts that determine Wollstonecraft as a traveller-cultural transmitter:
performativity and persona. This chapter demonstrates that the combination of persona (the self) and performativity (as
writer, observer and scholar) with the approach of cultural transfer expands our understanding of the
Letters.