bluuebunny/crossref_metadata_2025_split huggingface dataset:
Free Flap Elevation Times in Head and Neck Reconstruction Using the Harmonic Scalpel Shears
Authors: DeSerres Joshua J. , Barber Brittany R. , Seikaly Hadi , Harris Jeffrey R. , O’Connell Daniel A. 
Published: May 2016

Summary:
Free tissue transfer has become the mainstay of head and neck cancer (HNC) reconstructive surgery. The objective of the study is to examine the efficacy of the Harmonic Scalpel (HS) Shears on free flap elevation time and complication rates after HNC reconstruction compared with traditional electrocautery. A retrospective review of 215 HNC patients undergoing surgical ablation and free flap reconstruction from January 2010 to April 2013 at the University of Alberta Hospital was undertaken. All patients requiring free flap reconstruction with radial forearm free flap or fibula free flap were included. Overall, there was no significant difference demonstrated between the HS and electrocautery groups for free flap elevation time for RFFFs (P = 0.563) or FFFs (P = 0.087). No differences were observed in donor-site complications. The HS is a reliable, safe, and alternative method of free flap elevation in HNC reconstructive surgery.
Cognitive behavioral therapy for chronic pain is effective, but for whom?
Authors: Broderick Joan E. , Keefe Francis J. , Schneider Stefan , Junghaenel Doerte U. , Bruckenthal Patricia , Schwartz Joseph E. , Kaell Alan T. , Caldwell David S. , McKee Daphne , Gould Elaine 
Published: May 2016

Abstract
Moderator analyses are reported for posttreatment outcomes in a large, randomized, controlled effectiveness trial for chronic pain for hip and knee osteoarthritis (N = 256). Pain Coping Skills Training, a form of cognitive behavioral therapy, was compared to usual care. Treatment was delivered by nurse practitioners in patients' community doctors' offices. Consistent with meta-analyses of pain cognitive behavioral therapy efficacy, treatment effects in this trial were significant for several primary and secondary outcomes, but tended to be small. This study was designed to examine differential response to treatment for patient subgroups to guide clinical decision-making for treatment. Based on existing literature, demographic (age, sex, race/ethnicity, and education) and clinical variables (disease severity, body mass index, patient treatment expectations, depression, and patient pain coping style) were specified a priori as potential moderators. Trial outcome variables (N = 15) included pain, fatigue, self-efficacy, quality of life, catastrophizing, and use of pain medication. Results yielded 5 significant moderators for outcomes at posttreatment: pain coping style, patient expectation for treatment response, radiographically assessed disease severity, age, and education. Thus, sex, race/ethnicity, body mass index, and depression at baseline were not associated with level of treatment response. In contrast, patients with interpersonal problems associated with pain coping did not benefit much from the treatment. Although most patients projected positive expectations for the treatment prior to randomization, only those with moderate to high expectations benefited. Patients with moderate to high osteoarthritis disease severity showed stronger treatment effects. Finally, the oldest and most educated patients showed strong treatment effects, while younger and less educated did not.
An Open Source 3D-Printed Transitional Hand Prosthesis for Children
Authors: Zuniga Jorge M. , Peck Jean , Srivastava Rakesh , Katsavelis Dimitrios , Carson Adam 
Published: May 2016

ABSTRACT

Introduction
Advancements in computer-aided design programs, additive manufacturing, and open-source image editing software offer the possibility of designing, printing, and fitting transitional prosthetic hands and other prosthetic devices at very low cost. The development and use of 3D-printed transitional prosthetic devices to increase range of motion (ROM), strength, and other relevant variables would have a significant clinical impact for children with upper-limb deficiencies. Thus, the purpose of this study was to identify anthropometric, active ROM, and strength changes after 6 months of using a wrist-driven 3D-printed transitional prosthetic hand for children with upper-limb deficiencies.

Materials and Methods
Anthropometric, active ROM, and strength measurements were assessed before and after 6 months of using a 3D-printed transitional hand prosthesis. Five children (two girls and three boys, 3–10 years of age) with absent digits (one traumatic and four congenital) participated in this study and were fitted with a 3D-printed transitional hand prosthesis.

Results
There were significant hand × time interactions for the forearm circumference (p = 0.02), active ROM for flexion (p = 0.02), and extension values (p = 0.04). There were no significant hand × time interactions, however, for wrist flexion strength (p = 0.29), wrist extension strength (p = 0.84), active ROM for ulnar deviation (p = 0.5), active ROM for radial deviation (p = 0.25), and forearm skinfold values (p = 0.11).

Conclusion
Although durability, environment, and lack of printing standards for the manufacturing of 3D-printed prostheses are factors to consider when using these types of devices, the practicality and cost-effectiveness represent a promising new option for clinicians and those patients with upper-limb deficiencies living in developing countries. Thus, the Cyborg Beast transitional prosthetic hand represents a low-cost prosthetic solution for those in need of a transitional device to increase ROM and forearm circumference.
The Revolving Door Phenomenon in an Italian Acute Psychiatric Ward
Authors: Di Lorenzo Rosaria , Sagona Marco , Landi Giulia , Martire Lisa , Piemonte Chiara , Del Giovane Cinzia 
Published: May 2016

Abstract
To highlight the revolving door (RD) phenomenon in an acute psychiatric ward, we retrospectively identified the patients hospitalized three or more times in a calendar year from 1/1/2009 to 31/12/2013 as RD patients (RDP). We collected sociodemographic and clinical variables of RDP and statistically analyzed the potential RD risk factors. We divided RDP into “high” and “extremely high” utilizers and evaluated the variables related to more frequent readmissions. RDP represented 5.68% of all patients and their hospitalizations (RDH) 25% of all admissions. The statistically significant risk factors for all RDH were “disability pension,” “substance abuse/dependence,” “mild/severe aggressiveness,” and “psychiatric and social rehabilitative programs”. The comparison between “high” and “extremely high” utilizers showed that “manic episodes” and “personality disorders,” among the diagnoses, “familial relational conflicts” and “violence/suicidality”, among the hospitalization reasons, were statistically significant risk factors for more frequent readmissions. RD phenomenon was greatly affected by severe clinical conditions with social disability.
Acute Hemorrhagic Edema of Infancy
Authors: Ceci Maria , Conrieri Margherita , Raffaldi Irene , Pagliardini Veronica , Urbino Antonio Francesco 
Published: May 2016

Abstract
We report a case of acute hemorrhagic edema of infancy (AHEI) occurred in an 11-month-old male infant after upper respiratory tract infection. The onset was dramatic with petechiae, ecchymosis, and annular, nummular, or targetoid purpuric plaques on the extremities, face, and ears. Acute hemorrhagic edema of infancy is a benign form of leukocytoclastic vasculitis that typically affects children between 4 and 24 months of age. The etiology remains still unknown. The potential triggers of AHEI include preceding bacterial or viral infections, immunizations, and drugs. Although the clinical picture is fearful, in the majority of cases, it involves only cutaneous small vessels. Recognizing this as a distinct clinical entity allows to establish an appropriate prognosis for this rare benign disease in children.
This report could be a helpful reminder, especially for emergency physicians, to discriminate AHEI from other more severe diseases, such as meningococcal sepsis.
Common genetic variation drives molecular heterogeneity in human IPSCs
Authors: Kilpinen Helena , Goncalves Angela , Leha Andreas , Afzal Vackar , Ashford Sofie , Bala Sendu , Bensaddek Dalila , Casale Francesco Paolo , Culley Oliver , Danacek Petr , Faulconbridge Adam , Harrison Peter , McCarthy Davis , McCarthy Shane A , Meleckyte Ruta , Memari Yasin , Moens Nathalie , Soares Filipa , Streeter Ian , Agu Chukwuma A , Alderton Alex , Nelson Rachel , Harper Sarah , Patel Minal , Clarke Laura , Halai Reena , Kirton Christopher M , Kolb-Kokocinski Anja , Beales Philip , Birney Ewan , Danovi Davide , Lamond Angus I , Ouwehand Willem H , Vallier Ludovic , Watt Fiona M , Durbin Richard , Stegle Oliver , Gaffney Daniel J 
Published: May 2016

AbstractInduced pluripotent stem cell (iPSC) technology has enormous potential to provide improved cellular models of human disease. However, variable genetic and phenotypic characterisation of many existing iPSC lines limits their potential use for research and therapy. Here, we describe the systematic generation, genotyping and phenotyping of 522 open access human iPSCs derived from 189 healthy male and female individuals as part of the Human Induced Pluripotent Stem Cells Initiative (HipSci:http://www.hipsci.org). Our study provides a comprehensive picture of the major sources of genetic and phenotypic variation in iPSCs and establishes their suitability for use in genetic studies of complex human traits and cancer. Using a combination of genomewide analyses we find that 5-25% of the variation in different iPSC phenotypes, including differentiation capacity and cellular morphology, arises from differences betweenindividuals. We also assess the phenotypic effects of rare, genomic copy number mutations that are recurrently seen following iPSC reprogramming and present an initial map of common regulatory variants affecting the transcriptome of pluripotent cells in humans.
Specialization of a polyphenism switch gene following serial duplications inPristionchusnematodes
Authors: Ragsdale Erik J. , Ivers Nicholas A. 
Published: May 2016

AbstractPolyphenism is an extreme manifestation of developmental plasticity, requiring distinct developmental programs and the addition of a switch mechanism. Because the genetic basis of polyphenism switches has only begun to be understood, how their mechanisms arise is unclear. In the nematodePristionchus pacificus, which has a mouthpart polyphenism specialized for alternative diets, a gene (eud-1) executing the polyphenism switch was recently identified as the product of lineage-specific duplications. Here we infer the role of gene duplications in producing a switch gene. Using reverse genetics and population genetic analyses, we examine evidence for competing scenarios of degeneration and complementation, neutral evolution, and functional specialization. Of the daughter genes,eud-1alone has assumed switch-like regulation of the mouth polyphenism. Measurements of life-history traits in single, double, and triple sulfatase mutants did not, given modest sample sizes and a benign environment, identify alternative or complementary roles foreud-1paralogs. Although possible roles are still unknown, selection analyses of the sister species and 104 natural isolates ofP. pacificusdetected purifying selection on the genes, suggesting their functionality by their fixation and evolutionary maintenance. Our approach shows the tractability of reverse genetics in a non-traditional model system to study evolution by gene duplication.
Examining the relationships among the brand equity dimensions
Authors: Su Jin 
Published: May 2016

Purpose
– The purpose of this paper is to understand the nature of the inter-relationships among brand equity dimensions in the fast fashion context.

Design/methodology/approach
– Based on the empirical data collected from 419 fast fashion consumers in the USA, the study investigated the inter-relationships among the various brand equity dimensions by structural equation modeling.

Findings
– The findings reveal that brand awareness has a significant and positive direct impact on brand personality and perceived value; brand personality has a significant and positive direct effect on perceived quality and perceived value; and brand awareness, perceived quality and perceived value have a significant and positive direct effect on brand loyalty, respectively.

Originality/value
– Applying the brand equity model in the fast fashion industry and surveying actual consumers, the research provides in-depth empirical evidence of the interactions among the brand equity dimensions. Since fast fashion has become a key feature of the global fashion industry over the last decade, understanding the elements of brand equity and the inter-relationships among them provides important insights to marketing practitioners to develop strategies which encourage the growth of brand equity.
The effects of service quality on internet service provider customers’ behaviour
Authors: Quach Thu Nguyen , Jebarajakirthy Charles , Thaichon Park 
Published: May 2016

Purpose
– The purpose of this paper is threefold: first, to identify the dimensions for evaluating the service quality of internet service providers (ISPs); second, to investigate the relationship between service quality and customers’ behavioural intentions; and third, to investigate the influence of ISP customers’ usage patterns on their perceptions of ISP’s service quality dimensions.

Design/methodology/approach
– The study employs a sequential exploratory mixed method design incorporating quantitative and qualitative elements. Data in Study 1 was obtained from 2,059 internet users using an online survey. The relationships between the constructs of the proposed conceptual model were tested using structural equation modelling and the bias corrected bootstrapping technique. Also, the moderating effect of internet usage was examined. Study 2 featured 30 in-depth interviews with internet users.

Findings
– The findings reveal that dominant service quality dimensions for ISPs were network quality, customer service, information quality and privacy. The contribution of these factors to overall service quality was moderated by the internet usage. Results of Study 2 indicate that most respondents with heavy usage found network quality indifferent among ISPs and demonstrated hesitation in direct contact with customer service, making information support the most significant dimension. Additionally, service quality directly influenced customers’ complaining and switching intention. It was clarified in Study 2 that intention to continue the contract also depended on factors such as switching barriers, value and promotional offers.

Originality/value
– This study is original in that it is among the first studies to attempt to investigate the dimensions of an ISP’s service quality, and its influence on ISP customers’ behaviours. An additional contribution of the study stems from the incorporation of a sequential explanatory mixed methods approach.
Effect of family environment on adolescent compulsive buying: mediating role of self-esteem
Authors: Singh Rashmi , Nayak Jogendra Kumar 
Published: May 2016

Purpose– The purpose of this paper is to investigate the mediating role of self-esteem in the relationship between parent-adolescent relationship and adolescent compulsive buying behaviour. Using a sample of 300 adolescents (15-18 years) in India and the structural equation modelling technique, the findings reveal that self-esteem mediates the relationship between parent-adolescent relationship and adolescent compulsive buying behaviour.Design/methodology/approach– The present study is the first to experimentally manipulate important parent-adolescent relationship and measures its impact on compulsive buying among a sample of 15-18-year old adolescents. Next, the authors investigate the mediating role of self-esteem for the above relationship. Confirmatory factor analysis and structural equation modelling have been used in the study.Findings– The study also establishes that familial conflict and cohesion acts as major sources of adolescent compulsivity. The authors have also examined the mediating role of self-esteem on the above relationships and found that adolescents’ compulsivity varies with the level of self-esteem (i.e. higher level of self-esteem leads to lower levels of adolescents’ compulsivity). The practical and theoretical implications are discussed within the context of adolescents’ compulsivity.Originality/value– The study makes some inimitable and significant contributions to the literature. It portrays one of few studies to investigate compulsive buying during adolescence period – a hard to reach population. Here authors experimentally manipulate parent-adolescent relationship to investigate its impact on compulsive buying. The study’s findings in regard to mediating effect of self-esteem on the parent-adolescent relationship and adolescents’ compulsive buying behaviour suggest that compulsive buying begins during adolescence period and is a common coping strategy for both boys and girls.
Means-end chain approach for exploring the motivation of ready-to-drink tea consumers
Authors: Wang Edward Shih-Tse , Yu Jia-Rong 
Published: May 2016

Purpose
– Ready-to-drink (RTD) tea beverages are widely consumed worldwide and play a prominent role in people’s daily lives, yet few studies have investigated the motivation of RTD tea beverage consumers as well as their underlying attitudes and desires. The purpose of this paper is to explore why these attributes are motivational factors by focussing on the attributes of RTD tea beverage products that motivate consumers to purchase RTD tea.

Design/methodology/approach
– The attribute-consequence-value model of the means-end chain approach was employed to investigate consumer motivations for purchasing RTD tea beverages. Data were collected through a qualitative face-to-face survey of 153 RTD tea beverage consumers in Taiwan.

Findings
– The results indicate that consumers purchase RTD tea beverages because the taste, flavor, packaging, and ingredients (attributes) satisfy their desire to drink RTD tea and fulfill the benefits of being delicious to drink, possessing thirst-quenching properties, and possessing health-promoting properties (perceived consequences), thereby fulfilling their ideal goal of experiencing enjoyment (perceived product value).

Originality/value
– The findings may serve as a reference for producers of RTD tea beverages regarding product development and marketing.
Public expenditure, economic growth and poverty alleviation
Authors: Sasmal Ritwik , Sasmal Joydeb 
Published: May 2016

Purpose
– The purpose of this paper is to examine the impact of public expenditure on economic growth and poverty alleviation in developing countries like India. If poverty and inequality are high, the government may resort to distributive policies at the cost of long-term growth. The distributive policies and poverty alleviation measures fail to achieve success due to lack of good governance, lack of proper targeting and problems in the implementation of such schemes. On the other hand, if the nature of public expenditure is such that it enhances per capita income, it will help reduce poverty.

Design/methodology/approach
– After analytical digression and construction of hypotheses panel regression has been done using state-level data in the Indian context to empirically verify the above propositions. Both Fixed effects and Random effects models have been used for this purpose.

Findings
– The results show that in states where ratio of public expenditure on the development of infrastructure such as road, irrigation, power, transport and communication is higher, per capita income is also higher and incidence of poverty is lower indicating that economic growth is important for poverty alleviation and development of infrastructure is necessary for growth.

Originality/value
– This study demonstrates how public policy and public finance can be used as instruments for removal of poverty.
Diversification, family involvement and firm performance
Authors: Delbufalo Emanuela , Poggesi Sara , Borra Simone 
Published: May 2016

Purpose– The purpose of this paper is to investigate the effect of product and geographic diversification on the performance of Italian manufacturing firms and evaluate the moderating role of family involvement.Design/methodology/approach– The hypotheses have been tested by using a fixed-effects panel data regression model.Findings– Results show a linear relationship between product diversification and firm performance and an inverted U-shaped relationship between geographic diversification and firm performance. Moreover, when considering the status of the family firm, family ties have a negative moderating role on the performance of companies that are product and internationally diversified.Originality/value– By providing theoretical explanations and empirical evidence, the study extends the diversification-performance research by testing this relationship in an unexplored context (i.e. Italy), and by identifying a still not well explored contingency factor (i.e. family involvement). In doing so, diversification and family involvement literatures are brought together and the results show the importance of the type of owner regarding the impact of product and international diversification on firm performance.
Leadership Team Tool for better meaning making
Authors: Hedman Eerika 
Published: May 2016

Purpose– The purpose of this paper is to present a Leadership Team Tool for developing reflexivity in the context of leadership teams.Design/methodology/approach– The Leadership Team Tool is based on the theoretical premises of seeing communication as meaning making, and therefore placing discourse and conversation in the center of developing leadership teams.Findings– The paper illustrates how reflexivity can be facilitated through a structured process of using the Leadership Team Tool. An empirical investigation of using the tool in an authentic leadership team setting is warranted to further develop the Leadership Team Tool.Originality/value– The paper makes a practical contribution to several fields of studies, such as team communication and reflexivity, leadership team research and dialogic organization development. The paper addresses the need to develop solutions to enhance reflexivity, as prior research has not established the best ways to foster reflexivity.