bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of preoperative carbohydrate loading on the metabolic response to surgery in a low resource setting
Authors: Weledji E. P. , Njong S. N. , Chichom A. , Verla V. , Assob J. C. , Ngowe M. N. 
Published: June 2017

Abstract

Background
The stress response to surgery involves catabolism and gluconeogenesis resulting in postoperative hyperglycaemia. Postoperative hyperglycaemia is a risk factor for postoperative complications and preoperative fasting further aggravates this response. A carbohydrate (CHO) drink instead of fasting is expected to decrease insulin resistance and reduce post-operative hyperglycaemia. The aim of this study was to assess the effect of the reduction of the pre-operative fasting period on post-operative hyperglycaemia and post-operative complications in open surgery.

Methods
A hospital-based prospective case control study of 70 patients scheduled for elective surgery were sampled to either a case (carbohydrate-loaded) or a control (FAST) group. Postoperative hyperglycaemia and complications were the primary and secondary outcomes respectively reported.

Results
70 patients were recruited with 35 patients per group. 40 (57%) were females. The mean blood glucose on the first postoperative day was significantly higher in those who fasted (146.20 ± 38.36 mg/dl) than in those who received the energy drink (123.06 ± 26.64 mg/dl), p = 0.004. Postoperative infections were significantly higher in the control group than in the CHO group (31.43%; and 8.57%; 95% C.I: 1.23–19.47) p = 0.033. The mean length of hospital stay was longer in the FAST (12.54days ± 15.08) than in the CHO (9.17days ± 12.65) group although the difference was not statistically significant p = 0.315. The mean age, surgery type and mean duration of surgery were significant between groups but not upon logistic regression for significant clinical and demographic variables.

Conclusion
Preoperative CHO loading is effective and safe in reducing post-operative hyperglycaemia and infection in open general surgery even in a low resource setting.

Highlights
Microvascular changes in Down syndrome with Alzheimer's‐type pathology: Insights into a potential vascular mechanism for Down syndrome and Alzheimer's disease
Authors: Drachman David A. , Smith Thomas W. , Alkamachi Bassam , Kane Kevin 
Published: June 2017

AbstractIntroductionThe mechanism triggering degeneration in Alzheimer's disease (AD) remains uncertain. Therapeutic failure following amyloid β (Aβ) removal casts doubt on amyloid neurotoxicity per se as the primary cause of AD. Impaired microvascular function has been suggested as an alternative etiology. People with Down syndrome (DS) develop Alzheimer's pathology, but whether microvascular impairment also occurs in DS (as in AD) is unknown.MethodsWe examined brain microvasculature in five DS subjects with AD‐type histopathology, seven AD cases, and seven controls without AD‐type pathology. We counted microvessels in five anatomic regions and assessed endothelial integrity by CD31 immunohistochemistry.ResultsMicrovascular numbers and endothelial integrity were significantly diminished in DS brains compared with controls and were similar to AD brains.DiscussionPeople with DS and trisomy 21 produce a large amount of Aβ. If Alzheimer's pathology occurred in DS without microvascular loss or endothelial impairment, a direct neurotoxic Aβ mechanism would be supported and microvascular impairment rejected. The observation of microvascular impairment in DS with Alzheimer's disease changes fails to reject the microvascular hypothesis and provides some support for this potential mechanism of injury.
Decolonising Gender: Stories by, About and with Aboriginal and Torres Strait Islander Women
Authors: Rennie Sandra 
Published: June 2017

‘What is my story? Like you, I have many’, wrote feminist academic Sara Ahmed (Ahmed, 2010, p. 1). She asks, what is yours, what is mine? and begins her story at a table. ‘Around the table a family gathers’, she says, ‘Always we are seated in the same place. . .as if we are trying to secure more than our place’ (Ahmed, 2010, p. 1). In this paper, I draw upon Ahmed's work on willfulness and diversity work in higher education to explore the gendered stories of pathways through university shared with me by Indigenous Australian students. In the stories told in this paper, the table becomes the university space and the family becomes the students. The stories become more than securing place; they are stories which talk of willful resilience, resistance and persistence within that place called higher education. Grounded in my doctoral work with seven female Aboriginal and Torres Strait Islander students, this paper specifically focuses on the gendered nature of such willfulness to consider the ways in which Indigenous Australian students negotiate pathways and success through university within/against Western colonial and patriarchal institutions.
Integration based on the parametrisation of conics
Authors: Hoseana Jonathan 
Published: June 2017

Integration is an important topic discussed in first year calculus. Many subsequent topics, such as solving first-order or second-order differential equations, requires the evaluation of at least one integral, and sometimes several.The most challenging material in integration is arguably the techniques of integration. Unfortunately, due to time constraints, only basic techniques are commonly taught, while in reality, many integrals having special forms are solvable only by using more sophisticated techniques.
Coffee berry borer in conilon coffee in the Brazilian Cerrado: an ancient pest in a new environment
Authors: Oliveira C.M. , Santos M.J. , Amabile R.F. , Frizzas M.R. , Bartholo G.F. 
Published: June 2017

AbstractThe aim of this study was to verify the occurrence of the coffee berry borer,Hypothenemus hampei(Ferrari), and to evaluate the population fluctuation of the pest in the Brazilian Cerrado (Federal District). The study was conducted, between November 2014 and October 2015, at Embrapa Cerrados (Planaltina/DF, Brazil) in an irrigated conilon coffee production area. In November 2014, 120 samples (ten berries/sample) were collected from berries that had fallen on the ground from the previous harvest. Between November 2014 and October 2015, insects were collected weekly, using traps (polyethylene terephthalate bottles) baited with ethyl alcohol (98 GL), ethyl alcohol (98 GL) with coffee powder, or molasses. Between January and July 2015, samples were collected fortnightly from 92 plants (12 berries per plant). All samples were evaluated for the presence of adult coffee berry borers. Samples from the previous harvest had an attack incidence of 72.4%. The baited traps captured 4062H. hampeiadults, and showed no statistical difference in capture efficiency among the baits. Pest population peaked in the dry season, with the largest percentage of captured adults occurring in July (31.0%). An average of 18.6% of the collected berries was attacked by the borer and the highest percentage incidence was recorded in July (33.2%). Our results suggest that the coffee berry borer, if not properly managed, could constitute a limiting factor for conilon coffee production in the Brazilian Cerrado.
Association between intestinal helminth infections and mid-upper-arm circumference among children in Sri Lanka: A cross-sectional study
Authors: Galgamuwa L.S. , Iddawela D. , Dharmaratne S.D. 
Published: June 2017

AbstractIntestinal helminth infections constitute a major health problem in low socio-economic communities worldwide. A cross-sectional study was conducted in children aged between 12 and 60 months. A structured questionnaire was used to collect socio-demographic data and stool samples were subjected to direct smear, stained with Lugol's iodine, and formaldehyde–ether concentration techniques to determine the prevalence of intestinal helminth infections. The circumference of each child's left mid upper arm (MUAC) was measured using standard procedures. Two hundred and six children with a mean MUAC of 14.7 cm (SD ± 1.1) were assessed from September to December 2014. The prevalence of acute energy undernutrition was 6.3% (13/206). All of them had moderate acute undernutrition and no cases of severe acute undernutrition. Paternal occupation was significantly associated with MUAC. Intestinal helminth infections were detected in 12.6% of children. Four species of parasites were identified; Ascaris lumbricoides (9.7%) followed by Enterobius vermicularis (1.5%), Trichuris trichiura (1.0%) and hookworms (1.0%). Uninfected children aged between 1 and 2 years showed significantly higher MUAC than infected children. No statistically significant association was detected between the severity of intestinal helminth infections and MUAC. Although intestinal helminth infections are a major public health problem in this community, they are not related to MUAC. Future research, providing more insight into the nutritional impact of intestinal helminth infections, is required to determine the association between parasitic infections and physical growth in this community.
Challenges and opportunities of a landscape governance approach to the REDD+ programme: a conservation outlook
Authors: Mbatu Richard 
Published: June 2017

AbstractImplementing the Reducing Emissions from Deforestation and forest Degradation (REDD+) programme has the potential to significantly reduce greenhouse gases whilst also helping to maintain biodiversity. However, a proposed landscape governance approach to the REDD+ programme, encompassing all land-use activities, could alter these desirable outcomes. Under the proposed approach, governments and private entities could encourage types of land use that have the potential to threaten biodiversity and disrupt ecosystems. Yet a landscape governance approach could also stimulate governments to develop land-use management policies to facilitate adaptation to climate change. I organized focus group discussions with members of conservation groups, REDD+ scholars, and members of the REDD+ agroforestry research community at the Association of American Geographers 2016 Annual Meeting, to identify potential conservation challenges and opportunities associated with carbon-farming in grasslands and plantations under the proposed landscape governance approach to REDD+. I evaluate and synthesize this information, making recommendations for strategies to maximize the conservation opportunities and minimize the challenges. Understanding the challenges and opportunities will enable policy makers and other stakeholders to improve the presentation of their arguments in their efforts to shape the course of the REDD+ programme in the post-Paris Agreement era.
They ‘don't cure old age’: older Ugandans’ delays to health-care access
Authors: SCHATZ ENID , SEELEY JANET , NEGIN JOEL , MUGISHA JOSEPH 
Published: June 2017

ABSTRACTUganda's population is ageing, which comes with increased and varied burdens of disease and health-care needs. At the same time, gerontological care in Uganda remains neglected. This paper examines the factors that cause older Ugandans to delay health-care access. We conduct a thematic analysis of data drawn from nine focus groups held with rural Ugandans aged 60-plus. Our analysis highlights the factors that delay older persons’ access to health care and how these align with the Three-Delay Model, which was originally developed to assess and improve obstetric care in low-resource settings. Our participants report delays in deciding to seek care related to mobility and financial limitations, disease aetiology, severity and stigma (Delay I); reaching care because of poor roads and limited transportation options (Delay II); and receiving appropriate care because of ageism among health-care workers, and poorly staffed and under-supplied facilities (Delay III). We find these delays to care are interrelated and impacted by factors at the individual, community and health-system levels. We conclude by arguing for multi-pronged interventions that will address these delays, improve access to care and ultimately enhance older Ugandans’ health and wellbeing.
Legitimacy and institutional change in international organisations: a cognitive approach
Authors: Lenz Tobias , Viola Lora Anne 
Published: June 2017

AbstractWhy are some institutional designs perceived as more legitimate than others, and why is the same institutional design sometimes perceived as legitimacy-enhancing in one setting and not in another? In a world in which most international organisations (IOs) do not fully embody societal values and norms, such as democratic participation and equal treatment, why do legitimacy deficits in some organisations lead to pressure for institutional change while in others they are tolerated? These are important questions given that many analysts have diagnosed a ‘legitimacy crisis’ of IOs, but we argue that existing approaches are ill equipped to answer them. We show that the existing legitimacy literature has an implicit model of institutional change – the congruence model – but that this model has difficulty accounting for important patterns of change and non-change because it lacks microfoundations. We argue that attributions of legitimacy rest on perceptions and this implies the need to investigate the cognitive bases of legitimacy. We introduce a cognitive model of legitimacy and deduce a set of testable propositions to explain the conditions under which legitimacy judgments change and, in turn, produce pressures for institutional change in IOs.
SENTIMENTS, CONDUCT, AND TRUST IN THE LABORATORY
Authors: Smith Vernon L. , Wilson Bart J. 
Published: June 2017

Abstract:In this essay we provide a brief account and interpretation of The Theory of Moral Sentiments showing that it departs fundamentally from contemporary patterns of thought in economics that are believed to govern individual behavior in small groups, and contains strong testable propositions governing the expression of that behavior. We also state a formal representation of the model for individual choice of action, apply the propositions to the prediction of actions in trust games, report two experiments testing these predictions, and interpret the results in terms directly related to the model. In short, we argue that the system of sociability developed by Adam Smith provides a coherent non-utilitarian model that is consistent with the pattern of results in trust games, and leads to testable new predictions, some of which we test.
WHAT ECONOMICS CAN AND CANNOT SAY ABOUT EGALITARIAN REDISTRIBUTION
Authors: White Lawrence H. 
Published: June 2017

Abstract:I critically consider four purported economic-efficiency arguments for egalitarian redistribution of income or wealth. (1) Jeremy Bentham’s “greatest aggregate happiness” criterion has been used (by Bentham, John Stuart Mill, Alfred Marshall, A. C. Pigou, Abba Lerner, and more recently Richard Layard) to argue for wealth transfers toward the poor based on the supposition that they register higher happiness from a marginal dollar. Drawing from Vilfredo Pareto and Lionel Robbins, however, I argue that modern economic theory is not about individual happiness, let alone aggregate happiness, and therefore does not support (nor refute) any happiness-based case for wealth redistribution. (2) Theories based on a “social welfare function” misapply the economic way of thinking in a different way. (3) Other writers have framed redistribution as a public good, and public goods provision by the state as a voluntary collective means of satisfying individual preferences, thereby using modern economic theory to formulate a rationale for redistributive policies based on Pareto-efficiency. I criticize this rationale for resting on suppositions about actual preferences that are self-immunized against falsification. (4) James Buchanan made a related case for taxing inheritances based on the supposition that in constitutional deliberation behind a veil of ignorance we would agree to such a policy based on our preference for a certain kind of fairness. I find this argument non-economic, equally unfalsifiable, and no more plausible than alternative suppositions about our common preferences. The economic way of thinking does speak clearly, however, about how taxes on income or wealth discourage its production, the more so the higher the marginal tax rate.
BOYCOTTS AND THE SOCIAL ENFORCEMENT OF JUSTICE
Authors: Radzik Linda 
Published: June 2017

Abstract:This essay examines the ethics of boycotting as a social response to injustice or wrongdoing. The boycotts in question are collective actions in which private citizens withdraw from or avoid consumer or cultural interaction with parties perceived to be responsible for some transgression. Whether a particular boycott is justified depends, not only on the reasonableness of the underlying moral critique, but also on what the boycotters are doing in boycotting. The essay considers four possible interpretations of the kind of act in which boycotting consists: the avoidance of complicity, protest speech, social punishment, or social coercion. Each interpretation provides a plausible account of at least some cases of boycotting, yet each raises distinct challenges to justifying boycotting activities.
FORMS OF DIFFERENTIAL SOCIAL INCLUSION
Authors: Wolff Jonathan 
Published: June 2017

Abstract:Advocates of social equality need to develop an account of the society they favor. I have argued elsewhere that social equality should be conceived negatively: in terms of opposition to asymmetric and alienating relations such as hierarchy, domination and social exclusion, rather than in terms of a positive model of equality. This essay looks in detail at social exclusion, or rather “differential social inclusion,” and especially at the mechanisms that create exclusion and bind excluded groups together, and the consequent effects these mechanisms have on the reinforcement of inequality of opportunity and failure of social solidarity. Possible policies, such as improved social mobility, assertive self-affirmation, validation of subcultures, integration, and the creation of a large public sector are considered as possible responses to differential social inclusion in order to move closer to the idea of a society of equals.
PRACTICING PPE: THE CASE OF ADAM SMITH
Authors: Hanley Ryan Patrick 
Published: June 2017

Abstract:Adam Smith has long been celebrated as a polymath, and his wide interests in and contributions to each of the discrete component fields of PPE have long been appreciated. Yet Smith deserves the attention of practitioners of PPE today not simply for his substantive insights, but for the ways in which his inquiries into these different fields were connected. Smith’s inquiry was distinguished by a synthetic approach to knowledge generation, and specifically to generating knowledge with applications exportable to other fields. Further, Smith’s investigations of various areas of study led him to recognize patterns in and across these fields, and his sensitivity to such patterns helped guide his inquiry and render it a connected enterprise. This paper examines several of Smith’s discrete inquiries in the history of astronomy, language, moral philosophy, and political economy, to show how he employed the techniques of pattern detection that he practiced in each of these inquiries to the task of generating new insights into new fields of inquiry. In so doing, Smith not only distinguished himself as an early practitioner of what we today identify with PPE, but he also provides a useful point of reference for those doing PPE today.
MOST IMPORTANT BARRIERS AND FACILITATORS REGARDING THE USE OF HEALTH TECHNOLOGY ASSESSMENT
Authors: Cheung Kei Long , Evers Silvia M.A.A. , de Vries Hein , Hiligsmann Mickaël 
Published: June 2017

Objectives: Several studies have reported multiple barriers to and facilitators for the uptake of health technology assessment (HTA) information by policy makers. This study elicited, using best-worst scaling (BWS), the most important barriers and facilitators and their relative weight in the use of HTA by policy makers.Methods: Two BWS object case surveys (one for barriers, one for facilitators) were conducted among sixteen policy makers and thirty-three HTA experts in the Netherlands. A list of twenty-two barriers and nineteen facilitators was included. In each choice task, participants were asked to choose the most important and the least important barrier/facilitator from a set of five. We used Hierarchical Bayes modeling to generate the mean relative importance score (RIS) for each factor and a subgroup analysis was conducted to assess differences between policy makers and HTA experts.Results: The five most important barriers (RIS > 6.00) were “no explicit framework for decision-making process,” “insufficient support by stakeholders,” “lack of support,” “limited generalizability,” and “absence of appropriate incentives.” The six most important facilitators were: “availability of explicit framework for decision making,” “sufficient support by stakeholders,” “appropriate incentives,” “sufficient quality,” “sufficient awareness,” and “sufficient support within the organization.” Overall, perceptions did not differ markedly between policy makers and HTA experts.Conclusions: Our study suggests that barriers and facilitators related to “policy characteristics” and “organization and resources” were particularly important. It is important to stimulate a pulse at the national level to create an explicit framework for including HTA in the decision-making context.
On the origin and timing of Zika virus introduction in Brazil
Authors: MASSAD E. , BURATTINI M. NASCIMENTO , KHAN K. , STRUCHINER C. J. , COUTINHO F. A. B. , WILDER-SMITH A. 
Published: June 2017

SummaryThe timing and origin of Zika virus (ZIKV) introduction in Brazil has been the subject of controversy. Initially, it was assumed that the virus was introduced during the FIFA World Cup in June–July 2014. Then, it was speculated that ZIKV may have been introduced by athletes from French Polynesia (FP) who competed in a canoe race in Rio de Janeiro in August 2014. We attempted to apply mathematical models to determine the most likely time window of ZIKV introduction in Brazil. Given that the timing and origin of ZIKV introduction in Brazil may be a politically sensitive issue, its determination (or the provision of a plausible hypothesis) may help to prevent undeserved blame. We used a simple mathematical model to estimate the force of infection and the corresponding individual probability of being infected with ZIKV in FP. Taking into account the air travel volume from FP to Brazil between October 2013 and March 2014, we estimated the expected number of infected travellers arriving at Brazilian airports during that period. During the period between December 2013 and February 2014, 51 individuals travelled from FP airports to 11 Brazilian cities. Basing on the calculated force of ZIKV infection (the per capita rate of new infections per time unit) and risk of infection (probability of at least one new infection), we estimated that 18 (95% CI 12–22) individuals who arrived in seven of the evaluated cities were infected. When basic ZIKV reproduction numbers greater than one were assumed in the seven evaluated cities, ZIKV could have been introduced in any one of the cities. Based on the force of infection in FP, basic reproduction ZIKV number in selected Brazilian cities, and estimated travel volume, we concluded that ZIKV was most likely introduced and established in Brazil by infected travellers arriving from FP in the period between October 2013 and March 2014, which was prior to the two aforementioned sporting events.