bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing risk‐based inspection approach: Is it beneficial for pressure equipment in Malaysia industries?
Authors: Mohamed Ramuna , Che Hassan Che Rosmani , Hamid Mahar Diana 
Published: October 2017

The transition from time‐based inspection to risk–based inspection (RBI) in Malaysian industry began in June 2014 with the gazette of Factories and Machinery (Special Scheme of Inspection) (Risk‐Based Inspection) Regulations 2014 (SSI 2014). Under the new regulations, owners shall express their commitment and provide proof of their ability to ensure safety, integrity, and operability of relevant equipment. The regulation does not prescriptively mention methods to implement the RBI approach, but does spell out minimum requirements. Upon successful demonstration of compliance to the authority, the Certificate of Fitness of pressurized equipment may be extended to maximum 72 months.This paper aims to establish the benefits which may accrue from the adoption of RBI approach and ascertain the potential difficulties associated with the implementation of this approach. The paper first presents a review of the literature, establishing the major reasons for, and the benefits of, RBI implementation. This is followed by the results of a Malaysian survey on the implementation of RBM approach. An audit was conducted in the Malaysian petrochemical and chemical industries in April 2016. The audit results highlight the reasons for and benefits of implementing RBI. The paper concludes with a discussion and recommendations for the implementation of the RBI approach. © 2017 American Institute of Chemical Engineers Process Saf Prog 37: 194–204, 2018
An inquiry into the structure of situational interests
Authors: Azevedo Flávio S. 
Published: October 2017

AbstractI advance theoretically and empirically grounded arguments for broadening how we frame and understand situational interests. A situational interest refers to the short‐term spike in a person's attention and participation in an activity and it is triggered in the interactions between the person and environment features (e.g., novelty and surprise). As represented in the literature, extant conceptions of the phenomenon frame it fundamentally as a discontinuity in a person's experiences. Put differently, a situational interest denotes a moment in which a new object or activity is first brought into a person's stream of experiences and its triggering marks the boundary between two qualitatively distinct moments—a before‐and‐after—in one's ongoing activity participation. In contrast, I conjecture that situational interests are best understood as phenomena that combine both discontinuous and continuous dimensions of experience. To argue this point, I use three in‐depth videotaped case studies of the triggering and (when available) retriggering of situational interests in STEM‐based practices and show that the continuity + discontinuity lens provides a fine‐grained and more accountable description of the phenomenon, its triggering process, and its eventual uptake and development (or not).
Report of the International Stem Cell Banking Initiative Workshop Activity: Current Hurdles and Progress in Seed-Stock Banking of Human Pluripotent Stem Cells
Authors: Kim Jung-Hyun , Kurtz Andreas , Yuan Bao-Zhu , Zeng Fanyi , Lomax Geoff , Loring Jeanne F. , Crook Jeremy , Ju Ji Hyeon , Clarke Laura , Inamdar Maneesha S. , Pera Martin , Firpo Meri T. , Sheldon Michael , Rahman Nafees , O’Shea Orla , Pranke Patricia , Zhou Qi , Isasi Rosario , Rungsiwiwut Ruttachuk , Kawamata Shin , Oh Steve , Ludwig Tenneille , Masui Tohru , Novak Thomas J. , Takahashi Tsuneo , Fujibuchi Wataru , Koo Soo Kyung , Stacey Glyn N. 
Published: October 2017

Abstract
This article summarizes the recent activity of the International Stem Cell Banking Initiative (ISCBI) held at the California Institute for Regenerative Medicine (CIRM) in California (June 26, 2016) and the Korean National Institutes for Health in Korea (October 19–20, 2016). Through the workshops, ISCBI is endeavoring to support a new paradigm for human medicine using pluripotent stem cells (hPSC) for cell therapies. Priority considerations for ISCBI include ensuring the safety and efficacy of a final cell therapy product and quality assured source materials, such as stem cells and primary donor cells. To these ends, ISCBI aims to promote global harmonization on quality and safety control of stem cells for research and the development of starting materials for cell therapies, with regular workshops involving hPSC banking centers, biologists, and regulatory bodies. Here, we provide a brief overview of two such recent activities, with summaries of key issues raised.
Water Tolerant and Reusable Sulfonated Hyperbranched Poly(aryleneoxindole) Acid Catalyst for Solvent‐Free Esterification
Authors: Verheyen Thomas , Smet Mario , De Borggraeve Wim M. 
Published: October 2017

AbstractThe synthesis of esters directly from alcohols and carboxylic acids plays an important role in organic synthesis because of its utility in diverse fields both in academia and in industry. Innovations to further improve the efficiency and sustainability of the esterification process are highly desirable. To accomplish a green esterification protocol, we used a recoverable sulfonated hyperbranched poly(aryleneoxindole) acid catalyst in the condensation of various alcohols with acids. The protocol allows high conversion with equimolar amounts of reagents, recovery and reuse up to at least five times with solvent free conditions thus simplifying purification steps and reducing redundancy. Furthermore the reaction medium was deliberately spiked with water to evaluate its influence on the activity of the acid catalyst and excellent tolerance was observed.
One‐Pot Two Step Nazarov‐Schmidt Rearrangement for the Synthesis of Fused δ‐Lactam Systems
Authors: Thigulla Yadagiri , Ranga Santosh , Ghosal Subhas , Subbalakshmi Jayanty , Bhattacharya Anupam 
Published: October 2017

AbstractIn this article we have described a method to synthesize fused δ‐lactam compounds from chalcones, via a one pot two step route, involving consecutive application of Nazarov and Schmidt rearrangement reactions. Initial studies were done on 3‐phenyl‐1‐(thiophen‐3‐yl)prop‐2‐en‐1‐one, using polyphosphoric acid (PPA) and sodium azide at 120°C, whence the unexpected N‐alkyl amide product was obtained, instead of usual N‐aryl analogue. With diverse 3‐aryl substituted‐1‐(thiophen‐3‐yl)prop‐2‐en‐1‐one and 3‐aryl substituted‐1‐(thiophen‐2‐yl)prop‐2‐en‐1‐one as substrates, corresponding N‐alkyl amide compounds were obtained in modest to good yields. Interestingly, with 3‐aryl substituted phenylprop‐2‐en‐1‐one as substrates under the optimized conditions, N‐aryl amide compounds were formed as the final products instead of corresponding N‐alkyl analogues.
Proton Sponge Analogue of the Tröger's Base: A Compound with Remarkable Enantiomeric Stability
Authors: Ozeryanskii Valery A. , Vlasenko Marina P. , Pozharskii Alexander F. , Sergeyev Sergey , Maes Bert U. W. , Franck Philippe , Herrebout Wouter A. 
Published: October 2017

AbstractProton sponge analogue of the Tröger's base (4) has been obtained upon treatment of 1‐amino‐4,5‐bis(dimethylamino)naphthalene with paraformaldehyde. It was found that in contrast to classical Tröger's base 1, protonation of 4 occurs, at least thermodynamically, exclusively on peri‐NMe2 groups producing a dication with two chelated [NHN]+ hydrogen bonds. This prevents the protonation of the bridge nitrogen atoms, which is responsible for rather easy racemization of 1. Indeed, two enantiomers of 4 were resolved by chiral chromatography and their much higher stability in acidic media as compared to 1 has been confirmed. Some other properties of base 4 including structure, basicity, dynamic NMR behavior, host‐guest interactions and reactions with electrophiles are also discussed.
The Pericytic Phenotype of Adipose Tissue-Derived Stromal Cells Is Promoted by NOTCH2
Authors: Terlizzi Vincenzo , Kolibabka Matthias , Burgess Janette Kay , Hammes Hans Peter , Harmsen Martin Conrad 
Published: October 2017

Abstract
Long-term diabetes leads to macrovascular and microvascular complication. In diabetic retinopathy (DR), persistent hyperglycemia causes permanent loss of retinal pericytes and aberrant proliferation of microvascular endothelial cells (ECs). Adipose tissue-derived stromal cells (ASCs) may serve to functionally replace retinal pericytes and normalize retinal microvasculature during disease progression. We hypothesized that Notch signaling in ASC underlies regulation and stabilization of dysfunctional retinal microvascular networks such as in DR. ASC prominently and constitutively expressed NOTCH2. Genetic knockdown of NOTCH2 in ASC (SH-NOTCH2) disturbed the formation of vascular networks of human umbilical cord vein endothelial cells both on monolayers of ASC and in organotypical three-dimensional cocultures with ASC. On ASC SH-NOTCH2, cell surface platelet-derived growth factor receptor beta was downregulated which disrupted their migration toward the chemoattractant platelet-derived growth factor beta subunits (PDGF-BB) as well as to conditioned media from EC and bovine retinal EC. This chemoattractant is secreted by pro-angiogenic EC in newly formed microvascular networks to attract pericytes. Intravitreal injected ASC SH-NOTCH2 in oxygen-induced retinopathy mouse eyes did not engraft in the preexisting retinal microvasculature. However, the in vivo pro-angiogenic capacity of ASC SH-NOTCH2 did not differ from controls. In this respect, multifocal electroretinography displayed similar b-wave amplitudes in the avascular zones when either wild type ASC or SH-NOTCH2 ASC were injected. In conclusion, our results indicate that NOTCH2 is essential to support in vitro vasculogenesis via juxtacrine interactions. In contrast, ongoing in vivo angiogenesis is influenced by paracrine signaling of ASC, irrespective of Notch signaling.
Survivin Is Required for Mouse and Human Bone Marrow Mesenchymal Stromal Cell Function
Authors: Singh Pratibha , Fukuda Seiji , Liu Liqiong , Chitteti Brahmananda Reddy , Pelus Louis M. 
Published: October 2017

Abstract
Although mesenchymal stromal cells (MSCs) have significant potential in cell-based therapies, little is known about the factors that regulate their functions. While exploring regulatory molecules potentially involved in MSC activities, we found that the endogenous multifunctional factor Survivin is essential for MSC survival, expansion, lineage commitment, and migration. Pharmacological or genetic blockade of Survivin expression in mouse and human bone marrow MSC enhances caspase 3 and 7 expression and reduces proliferation resulting in fewer MSC and clonogenic colony-forming unit-fibroblasts (CFU-F), whereas ectopic Survivin overexpression in MSC results in their expansion. Survivin is also required for the MSC proliferative responses to basic fibroblast growth factor and platelet derived growth factor. In a wound healing model, Survivin inhibition results in suppression of MSC migration to the wound site. In addition, loss of Survivin in MSCs compromises their hematopoiesis-supporting capacity. These results demonstrate that Survivin is a key regulator of mouse and human MSC function, and suggest that targeted modulation of Survivin in MSCs may have clinical utility to enhance MSC recovery and activity following insult or stress.
Nitrogen and white clover impacts on the management of perennial ryegrass–clover swards for grazing cattle
Authors: McDONAGH J. , GILLILAND T. J. , McEVOY M. , DELABY L. , O'DONOVAN M. 
Published: October 2017

SUMMARYPerennial ryegrass and white clover (WC) have been shown to form compatible mixtures for pasture production under temperate climates. The inclusion of WC has the potential to enhance the performance of grass swards, but the extent of the improvement under contrasting grazing management strategies is unclear. Grazing rotation and fertilizer nitrogen (N) use have been identified as two major factors that can influence the performance of grass–clover swards. The objective of the current study was to examine the effect of differing grazing rotation lengths and the level of N application on the dry matter (DM) yield performance of grass–clover and grass-only swards as well as on WC productivity and persistency under animal grazing. Swards were managed by N application and grazing rotation length: High-N swards were managed on a 21-day grazing rotation (Man 1) and low-N swards were managed on a 30-day grazing rotation (Man 2). The four treatments were: 250 kg N/ha without WC (HN−C), 250 kg N/ha with WC (HN+C), 100 kg N/ha N without WC (LN−C) and 100 kg N/ha with WC (LN+C). There was a significant management × WC interaction over the 3 years for annual DM yield. The LN−C swards produced lower DM yield (−1917 kg DM/ha) than the swards of the other three treatments (11 167 kg DM/ha). Management had a significant effect on annual DM yield with Man 1 swards yielding 801 kg DM/ha more than Man 2 swards (10 288 kg DM/ha). The inclusion of WC yielded significantly more annual DM yield (+1009 kg DM/ha) than grass-only swards. Notably, LN+C produced the same annual total DM yield as swards under High N and a 21-day grazing rotation. Total WC DM yield and proportion across the year was altered significantly by management. Higher N fertilized swards at shorter grazing intervals had a lower WC DM yield (−1544 kg DM/ha) and proportion (−0·13). Dry matter yield of WC with low N application can be similar to that at high N levels if rotation length is used as a mechanism to determine grazing timing. Variations in WC productivity into the final year of the experiment indicate that persistence of significant contributions to DM yield by WC under low N at longer grazing intervals remains unclear after 3 years.
Forced magnetic reconnection
Authors: Vekstein G. 
Published: October 2017

This is a tutorial-style selective review explaining basic concepts of forced magnetic reconnection. It is based on a celebrated model of forced reconnection suggested by J. B. Taylor. The standard magnetohydrodynamic (MHD) theory of this process has been pioneered by Hahm & Kulsrud (Phys. Fluids, vol. 28, 1985, p. 2412). Here we also discuss several more recent developments related to this problem. These include energetics of forced reconnection, its Hall-mediated regime, and nonlinear effects with the associated onset of the secondary tearing (plasmoid) instability.
How postcolonial is post-Western IR? Mimicry and mētis in the international politics of Russia and Central Asia
Authors: Owen Catherine , Heathershaw John , Savin Igor 
Published: October 2017

AbstractScholars of International Relations have called for the creation of a post-Western IR that reflects the global and local contexts of the declining power and legitimacy of the West. Recognising this discourse as indicative of the postcolonial condition, we deploy Homi Bhabha’s concept of mimicry and James C. Scott’s notion of mētis to assess whether international political dynamics of a hybrid kind are emerging. Based on interviews with Central Asian political, economic, and cultural elites, we explore the emergence of a new global politics of a post-Western type. We find that Russia substantively mimics the West as a post-Western power and that there are some suggestive examples of the role of mētis in its foreign policy. Among Central Asian states, the picture is more equivocal. Formal mimicry and mētis of a basic kind are observable, but these nascent forms suggest that the dialectical struggle between colonial clientelism and anti-colonial nationalism remains in its early stages. In this context, a post-Western international politics is emerging with a postcolonial aspect but without the emergence of the substantive mimicry and hybrid spaces characteristic of established postcolonial relations.
Do Not Cross the Line: The State Influence on Religious Education
Authors: Giorgi Alberta , Annicchino Pasquale 
Published: October 2017

AbstractThe issues related to the role of religion in the public education system have been a public topic for a long time, and related debates have been cyclically revived by specific events. In this contribution, we explore the reasons why Italian grassroots actors do not tend to size up the European Court of Human Rights (ECtHR) jurisprudence and the plurality of juridical regimes dealing with religion and education as windows of opportunity. First, we analyze the intertwinement of different juridical regimes dealing with religion and education, and the national case law on the topic. Then, drawing on original semi-structured interviews, we analyze the indirect effects of the ECtHR case law on the mobilizations and advocacy strategies at the grassroots level around religion and education. Finally, we discuss the research outcomes, outlining how the non-interference of the Court in state-religions regimes may result in the limited impact and effectiveness of the Court's protection of religious freedoms.
What If Applicants Knew How Personality Tests are	Scored?
Authors: König Cornelius J. , Jansen Anne , Mathieu Peter Lüscher 
Published: October 2017

Abstract. Having access to information on personality tests might make faking of personality tests easier because applicants are not hindered by incorrect assumptions about the scoring. Thus, this experiment tests whether very briefly telling applicants how personality tests are scored affects faking. Management assistants (N = 187), asked to imagine themselves as job applicants, were either informed about the scoring key or given no information before filling out a Big Five personality test. Results revealed that this minimal manipulation increased faking. This finding supports the notion that applicants often incorrectly assume that scoring procedures are overly complex and gives practitioners additional reason to worry about more future faking.
Psychological Contract Fulfillment and Employee Responses to Pay	System Change
Authors: Syrek Christine J. , Antoni Conny H. 
Published: October 2017

Abstract. The implementation of a new pay system is a balancing act that produces uncertainty and draws employees’ attention to the fulfillment of exchange agreements. Transformational leadership may be essential during these change processes. Based on psychological contract theory, we expected that transformational leadership impacts job satisfaction and affective organizational commitment through the fulfillment of relational psychological contracts, while the fulfillment of transactional psychological contracts may be crucial for employees’ pay and bonus satisfaction. We assessed 143 employees nested within 34 teams before and after (24 months) a pay for performance (pfp) system was introduced. Our results supported the mediation hypotheses considering job and pay satisfaction, but not considering commitment. Unexpectedly, the effect on bonus satisfaction was mediated via relational psychological contracts.
Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development
Authors: Vallecillo-García Pedro , Orgeur Mickael , vom Hofe-Schneider Sophie , Stumm Jürgen , Kappert Verena , Ibrahim Daniel M. , Börno Stefan T. , Hayashi Shinichiro , Relaix Frédéric , Hildebrandt Katrin , Sengle Gerhard , Koch Manuel , Timmermann Bernd , Marazzi Giovanna , Sassoon David A. , Duprez Delphine , Stricker Sigmar 
Published: October 2017

AbstractFibro-adipogenic progenitors (FAPs) are an interstitial cell population in adult skeletal muscle that support muscle regeneration. During development, interstitial muscle connective tissue (MCT) cells support proper muscle patterning, however the underlying molecular mechanisms are not well understood and it remains unclear whether adult FAPs and embryonic MCT cells share a common lineage. We show here that mouse embryonic limb MCT cells expressing the transcription factor Osr1, differentiate into fibrogenic and adipogenic cells in vivo and in vitro defining an embryonic FAP-like population. Genetic lineage tracing shows that developmental Osr1+ cells give rise to a subset of adult FAPs. Loss of Osr1 function leads to a reduction of myogenic progenitor proliferation and survival resulting in limb muscle patterning defects. Transcriptome and functional analyses reveal that Osr1+ cells provide a critical pro-myogenic niche via the production of MCT specific extracellular matrix components and secreted signaling factors.
A highly flexible and sensitive piezoresistive sensor based on MXene with greatly changed interlayer distances
Authors: Ma Yanan , Liu Nishuang , Li Luying , Hu Xiaokang , Zou Zhengguang , Wang Jianbo , Luo Shijun , Gao Yihua 
Published: October 2017

AbstractSince the successful synthesis of the first MXenes, application developments of this new family of two-dimensional materials on energy storage, electromagnetic interference shielding, transparent conductive electrodes and field-effect transistors, and other applications have been widely reported. However, no one has found or used the basic characteristics of greatly changed interlayer distances of MXene under an external pressure for a real application. Here we report a highly flexible and sensitive piezoresistive sensor based on this essential characteristics. An in situ transmission electron microscopy study directly illustrates the characteristics of greatly changed interlayer distances under an external pressure, supplying the basic working mechanism for the piezoresistive sensor. The resultant device also shows high sensitivity (Gauge Factor ~ 180.1), fast response (<30 ms) and extraordinarily reversible compressibility. The MXene-based piezoresistive sensor can detect human being’s subtle bending-release activities and other weak pressure.
Earliest accumulation of β-amyloid occurs within the default-mode network and concurrently affects brain connectivity
Authors: Palmqvist Sebastian , Schöll Michael , Strandberg Olof , Mattsson Niklas , Stomrud Erik , Zetterberg Henrik , Blennow Kaj , Landau Susan , Jagust William , Hansson Oskar 
Published: October 2017

AbstractIt is not known exactly where amyloid-β (Aβ) fibrils begin to accumulate in individuals with Alzheimer’s disease (AD). Recently, we showed that abnormal levels of Aβ42 in cerebrospinal fluid (CSF) can be detected before abnormal amyloid can be detected using PET in individuals with preclinical AD. Using these approaches, here we identify the earliest preclinical AD stage in subjects from the ADNI and BioFINDER cohorts. We show that Aβ accumulation preferentially starts in the precuneus, medial orbitofrontal, and posterior cingulate cortices, i.e., several of the core regions of the default mode network (DMN). This early pattern of Aβ accumulation is already evident in individuals with normal Aβ42 in the CSF and normal amyloid PET who subsequently convert to having abnormal CSF Aβ42. The earliest Aβ accumulation is further associated with hypoconnectivity within the DMN and between the DMN and the frontoparietal network, but not with brain atrophy or glucose hypometabolism. Our results suggest that Aβ fibrils start to accumulate predominantly within certain parts of the DMN in preclinical AD and already then affect brain connectivity.