bluuebunny/crossref_metadata_2025_split huggingface dataset:
Topological Characterization of Coronoid Structures via Valency Based Topological Indices
Authors: Masood Ur Rehman  , Salman Muhammad , Iqbal Javaria 
Published: October 2024

Background:
The number of atoms producing a bond with an atom a in a molecular
structure (graph) is regarded as the valency of a. A number of molecular structures have been
topologically characterized via a large number of valency-based topological indices, which correlate
certain physio-chemical properties like boiling point, stability, strain energy, and many
more chemical compounds.

Objective:
Our intention is to perform the topological characterization of primitive coronoid
structures initially on the base of seven different valency-based topological indices. Fundamentally,
our purpose is to provide the universal formula by using the topological characterization of
any primitive coronoid structures with any valency-based topological index.

Method:
The technique of atom-bonds partitions according to the valency of atoms besides
counting principals are used to find the results.

Results:
Exact values of valency-based topological index, namely the Randic index, sum connectivity
index, harmonic index, atom bond connectivity index, geometric arithmetic index, forgotten
index, and symmetric division index are calculated coronoid structures initially constructed
with at most three benzene lyres. All these indices are valency-dependent structural invariants
that have been used to elaborate several chemical properties of compounds of the structure.

Conclusion:
Moreover, we provide the general formula to compute any valency-based topological
index for any type of coronoid structure constructed with any number of benzene lyres.
Identification of Novel Tyrosinase Inhibitors with Nanomolar Potency Using Virtual Screening Approaches
Authors: Liu Guohong , Liu Shihao , Li Xiaofang , Wang Tegexibaiyin 
Published: October 2024

Introduction:
Hyperpigmentation disorders are caused by excess production of the pigment
melanin, catalyzed by the enzyme tyrosinase. Novel tyrosinase inhibitors are needed as therapeutic
agents to treat these conditions.

Method:
To discover new inhibitors, we performed a virtual screening of the ZINC20 library containing
1.4 billion compounds. An initial filter for drug-likeness, ADMET properties, and synthetic
accessibility reduced the library to 10,217 hits. Quantitative structure-activity relationship
(QSAR) modeling of this subset predicted nanomolar inhibitory potency for several chemical scaffolds.
Comparative molecular docking studies and rigorous binding energy calculations further prioritized
four cysteine-containing dipeptide compounds based on predicted strong binding affinity
and mode to tyrosinase.

Results:
Microsecond-long molecular dynamics simulations provided additional atomistic insights
into the stability of inhibitor-enzyme binding interactions. This integrated computational workflow
effectively sampled an extremely large chemical space to discover four novel tyrosinase inhibitors
with half-maximal inhibitory concentration values below 10 nM.

Conclusion:
Overall, this demonstrates the power of virtual screening and multi-faceted computational
techniques to accelerate the discovery of potent bioactive ligands from massive compound
libraries by efficiently sampling chemical space.
Cardiology Consult for the General Pediatrician after Cardiac Manifestations from a SARS-CoV-2 Infection
Authors: Amdani Shahnawaz , Altman Carolyn A. , Chowdhury Devyani , Ronai Christina , Soma David , Archer Jeremy M. , Tierney Seda , Renno Marukus S. , Miller Jacob , Nguyen Quang-Tuyen , Glickstein Julie S. , Orr William B. 
Published: October 2024

Abstract:
The novel Coronavirus Disease 2019 (COVID-19), caused by the SARS-CoV-2 virus,
created a need for evidence-based guidelines for the evaluation, management, and follow-up after
infection. Data have become rapidly available, creating a challenge for medical providers to stay
abreast of the ever-evolving recommendations. This document, written collaboratively by pediatric
cardiovascular experts, pediatricians, and sports medicine specialists, is focused on SARS--
CoV-2-related pediatric cardiac manifestations. It aims to provide a systemic review of high-yield
literature related to all cardiovascular entities as a tool for primary pediatric clinicians to utilize as
they consider the cardiac consequences of acute SARS-CoV-2 infection, MIS-C, vaccine-related
myocarditis, return-to-play, and long COVID-19 syndrome.
A Comprehensive Analysis of the Types, Impacts, Prevention, and Mitigation of DDoS Attacks
Authors: Poonia Laxmi , Tinker Seema 
Published: October 2024

Background:
DDoS attacks, where numerous compromised systems overwhelm a target
with traffic, are significant threats to online services' stability. These attacks exploit the fundamentals
of internet communication, using botnets to flood targets and deplete their resources, severely
reducing performance. The strength of DDoS attacks lies in their distributed nature, which complicates
the differentiation between legitimate and malicious traffic. As digital reliance grows, so does
the significance of these attacks, which impact businesses, governments, and public services crucial
for operations.

Objective:
The paper aims to provide a comprehensive understanding of DDoS attacks, categorizing
them into bandwidth and resource depletion, infrastructure, and zero-day attacks. It seeks to highlight
the complexity and impact of these attacks, particularly those utilizing IoT botnets, on internet reliability
and security. The study emphasizes the limitations of current defense mechanisms, advocating
for improved strategies that consider the distributed nature of these threats. Through this analysis, the
paper aims to foster a deeper understanding of DDoS attacks, their consequences, and the need for
more effective mitigation and prevention techniques.

Methods:
The study employs an in-depth literature review to classify DDoS attacks and explore
various mitigation strategies. It provides a detailed examination of attack mechanisms, including
bandwidth depletion, resource depletion, infrastructure attacks, and zero-day vulnerabilities. The
paper discusses several defense techniques, such as filtering, intrusion detection systems, and advanced
AI and machine learning approaches. It emphasizes the role of IoT devices in amplifying
DDoS attacks and the challenges of defending against these evolving threats.

Result:
The paper identifies four main categories of DDoS attacks and describes their operational
mechanisms, impacts, and mitigation challenges. It reveals that due to inadequate security measures,
IoT devices significantly contribute to the scale and impact of DDoS attacks. Despite the various
defense mechanisms discussed, the paper points out their limitations in effectively countering the
evolving nature of DDoS attacks. It emphasizes the need for more robust, adaptive strategies incorporating
technological advancements and better security practices in IoT device manufacturing.

Conclusion:
DDoS attacks, particularly those leveraging IoT botnets, pose increasingly sophisticated
threats to digital infrastructure. The paper underscores the urgent need for more effective defense
mechanisms, highlighting the importance of technological advancements, better IoT security, and
collaborative efforts among stakeholders. It calls for future research focused on developing AIdriven
systems for real-time prediction and mitigation of attacks, as well as the formulation of international
cyber-security policies to address the growing menace of DDoS attacks in a globally connected
environment.
Influence of Rubber Distribution and Shape on Properties of Thermoplastic Vulcanizate: Finite Element Modeling
Authors: Li Longhao , Ma Lifeng , Liu Congchao , Wei Jingyi 
Published: October 2024

Introduction:
Thermoplastic vulcanizate (TPV), as a rapidly developing
green engineering material, its microstructure determines its comprehensive mechanical
properties. However, there are few reports on the influence of the distribution and
shape of rubber particles on the overall properties of TPV.

Method:
In order to overcome the shortcoming that traditional experimental methods
cannot obtain the internal stress change process of materials, we have established a
series of representative volume element (RVE) models with different particle distributions
and shapes through the micromechanical finite element method.

Results:
The uniaxial tension and tension recovery of the models have been simulated.
The results show that with the change of particle distribution and shape, the minimum
elastic modulus of TPV based on ethylene propylene diene monomer (EPDM) /
polypropylene (PP) could reach 31.4 MPa and the highest resilience could reach
87.4%.

Conclusion:
In addition, it can be seen from the stress distribution nephogram that
the change in particle distribution and shape would obviously change the position of
the stress concentration area in TPV.
Technology innovation in library: a bibliometric review
Authors: Margono Hendro , Rasyid Rizka Adristi , Setiyarini Melina Dewi 
Published: October 2024

Technological innovation is changing libraries and how libraries operate. This study presents a bibliometric analysis to identify key patterns and trends in research on technological innovation in libraries, based on the publication of papers indexed in Web of Science from 2019 to 2023. A total of 433 documents from 342 sources were analyzed using Biblioshiny and VOSViewer software. The results show an increasing interest in this research domain, despite a negative annual publication growth rate of -32.33% in recent years. The IEEE Winter Conference on Computer Vision Applications and the IEEE Symposium on Security and Privacy were the most productive sources. "Library" was the most frequent keyword found in 6% of documents, along with terms such as "model", "performance", and "system", highlighting the focus on developing and evaluating technological systems for libraries. The findings summarize the key topics, trends, and leading countries driving technology innovation research for libraries over the past five years. This bibliometric review provides insights to guide future research efforts in this area.
Racial and Ethnic Differences in Traumatic Brain Injury Outcomes From 2009 to 2023: Protocol for a Systematic Review
Authors: Pappadis Monique R , Talley Kelli G , Garcia Patricia , Aguirre Caitlin R , Onwudebe Chinedu K , Smith Michelle , Lequerica Anthony H 
Published: October 2024

Background
In 2009, Gary and colleagues reviewed prior research examining racial and ethnic differences in outcomes after traumatic brain injury (TBI). Over the past 15 years, advances in research and changes in the demographic composition of the United States warrant a comprehensive understanding of racial and ethnic disparities after TBI.

Objective
A systematic review will be conducted to examine racial and ethnic differences in TBI outcomes from 2009 to 2023.

Methods
Preliminary searches and study screening processes will identify relevant English-language articles published from January 2009 to December 2023 using the CINAHL, Gale OneFile, PsycINFO (Ovid), and PubMed electronic databases. Relevant articles will include quantitative or mixed method approaches, involve individuals with TBI or their caregivers, and compare 2 or more groups by race or ethnicity on post-TBI outcomes. Quality will be assessed using the Newcastle-Ottawa Scale. This systematic review protocol was developed following PRISMA-P (Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols) guidelines. Results will be summarized, and a subgroup analysis may be conducted based on demographics (eg, age, gender, or sex).

Results
We have already identified abstracts using the search strategy for all 4 of the included electronic databases. We recently updated the search and will begin abstract screening of the additional abstracts identified from the last search completed in January 2024. This systematic review is anticipated to be completed by fall 2024, and its findings will be disseminated to the scientific community, persons with TBI, caregivers, and the lay audience.

Conclusions
This systematic review will advance our understanding regarding outcome disparities among minoritized individuals with TBI, examine progress over the past 15 years in minimizing barriers encountered by these racial and ethnic groups, and provide professionals with a roadmap illustrating existing gaps in rehabilitation care, making way for further development and implementation of evidence-based interventions to improve health equity in TBI outcomes.

Trial Registration
PROSPERO CRD42023394529; https://tinyurl.com/53mtcz9b

International Registered Report Identifier (IRRID)
PRR1-10.2196/58763
Eksistensialisme Wanita: Studi Kasus Cerpen ‘Catatan Hati Seorang Istri’ pada Karakter Religius
Authors: Hartini  , Widayanti Mukti , Sudiyana Benedictus 
Published: October 2024

Perbedaan peran antara perempuan dengan laki-laki dapat mempengaruhi penulisan sejumlah karya sastra di Indonesia. Cerpen Catatan Hati Seorang Istri karangan Asma Nadia menggambarkan dunia perempuan yang memiliki berbagai permasalahan. Dunia perempuan yang meliputi citra diri perempuan, pikiran, tingkah laku, sikap, dan perasaan secara implisit dan eksplisit di dalam novel tersebut. Penelitian ini bertujuan untuk mendeskripsikan konstruksi pandangan feminisme eksistensial dan keterkaitan cerpen Catatan Hati Seorang Istri dengan penguatan karakter religius. Penelitian menggunakan pendekatan deskriptif kualitatif. Teknik pengumpulan data dalam penelitian ini menggunakan teknik baca dan teknik catat. Teknik analisis data menggunakan metode dialektik. Hasil penelitian menunjukkan bahwa pandangan feminisme eksistensial dapat dilihat adanya bentuk ketidakadilan gender, diantaranya kekerasan fisik; pelecehan; selingkuh dan poligami. Ketidakadilan yang dialami oleh istri menimbulkan dampak negatif dalam sebuah rumah tangga, antara lain: ketidakbahagiaan rumah tangga; perselingkuhan dan perceraian. Penguatan karakter religius dalam cerpen tersebut dapat dinilai dari unsur Aqidah; nilai Akhlak dan unsur Ibadah. Nilai aqidah terbagi menjadi dua yaitu keyakinan dan ketetapan. Dalam nilai akhlak, terkandung adanya perbedaan dua karakter yang berlawanan, yakni akhlak terpuji yang dimiliki oleh para istri yang bersikap sabar dan ikhlas. Sebaliknya, akhlak tercela dimiliki oleh para suami yang melanggar ikatan suci pernikahan. Dalam unsur ibadah yang bersifat khusus adalah melakukan taqarrub (mendekatkan diri) kepada Allah. yaitu dengan mematuhi segala perintah-Nya, meninggalkan semua larangan-Nya dan menjalankan segala sesuatu yang dihalalkan Allah. Adapun beribadah secara umum adalah segala amalan yang diizinkan Allah.
Практические аспекты решения задачи селекции корпоративных девелоперских проектов
Authors: Изюмов Максим Дмитриевич 
Published: October 2024

В современном мире корпоративные девелоперские проекты играют важную роль в развитии бизнеса. От эффективности реализации этих проектов во многом зависит успех компании. Автором рассмотрены практические аспекты решения задачи селекции корпоративных девелоперских проектов с акцентом на необходимость комплексного подхода к принятию решения о реализации проекта.
Рассмотрены различные стратегии, которые применяются в процессе управления портфелем корпоративной недвижимости. Многообразие стратегий обуславливает необходимость формирования многосоставного перечня критериев для решения задачи селекции проектов девелопмента, реализуемых в рамках управления портфелем корпоративной недвижимости. Разработан перечень критериев, включающий в себя три группы параметров проектов: финансово-экономические, экологические и управленческие. В качестве критерия общей эффективности предлагается использовать социальный возврат на инвестиции, который входит в группу финансово-экономических критериев, совместно с капиталоемкостью, масштабностью и совокупной стоимостью владения. Экологические критерии учитывают такие параметры объекта недвижимости, как наличие различных сертификатов, класс энергоэффективности, а также внедрение автоматизированных систем управления зданием. Управленческие критерии позволяют оценить соответствие проекта общей стратегии корпорации, поэтому в данную группу входят такие параметры, как: срок ввода в эксплуатацию, формат реализации проекта, а также обеспеченность сотрудников площадью.
Для принятия итогового решения автором предлагается использовать метод анализа иерархий, широко применяемый в различных отраслях при решении подобных задач. Представлены методические основы, а также практический пример применения данного метода.
Новые тренды развития кафедры ОСУН. Как прошла производственная практика студентов МГСУ на АЭС «Аккую»
Authors: Моттаева Анджела Бахуовна , Баранова Анна Сергеевна , Валуев Егор Иванович , Варганов Илья Евгеньевич , Грабовой Артём Леонидович 
Published: October 2024

В статье рассказывается о том, как на кафедре «Организация строительства и управления недвижимостью» (ОСУН) МГСУ было положено начало еще одной, новой уникальной традиции — организации зарубежной производственной практики студентов. В соответствии с достигнутыми договоренностями прошла зарубежная стажировка студентов кафедры ОСУН на АЭС «Аккую» в Турецкой Республике. Государственная корпорация по атомной энергии «Росатом» — многопрофильный холдинг, объединяющий активы в энергетике, машиностроении, строительстве. АЭС «Аккую» — первая атомная электростанция в Турецкой Республике. Проект первой турецкой АЭС включает в себя четыре энергоблока с реакторами российского дизайна ВВЭР-1200. Сооружение АЭС «Аккую» — первый проект в мировой атомной отрасли, реализуемый по модели Build-Own-Operate. Кафедра ОСУН осуществляет свою деятельность на протяжении более 90 лет, имеет свою историю и устоявшиеся традиции. Идя в ногу со временем, принимая во внимание нынешние инновационные тренды и вызовы в сфере строительства, экономики, образования, на кафедре была организована зарубежная стажировка студентов. С какими же трудностями они столкнулись и почему этот «пилотный проект» является очень ценным, знаковым опытом не только для кафедры, но и для НИУ МГСУ в целом. По итогам совместного проекта можно отметить, что поставленные цели и задачи решены. Стороны остались довольны результатами, отметили важность такого формата сотрудничества и запланировали дальнейшие взаимоотношения.
Экологический менеджмент в строительстве: тенденции, уровни управления, показатели
Authors: Симионов Радомир Юрьевич , Кирпиченков Андрей Андреевич 
Published: October 2024

Сохранение окружающей природной среды во многом зависит от повышения экологической ответственности строительных организаций. Статистические данные показывают, что последние годы характеризуются ростом объемов работ по виду экономической деятельности «Строительство», что требует организационных, правовых, экономических, технологических и технических мер, реализуемых на государственном, отраслевом уровнях и в системе управления строительными организациями, направленных на рациональное природопользование. Эти меры относятся не только к стадии строительства объектов, но и периоду эксплуатации объектов недвижимости, что обусловлено значительной ресурсоемкостью объектов недвижимости как в процессе строительства, так и эксплуатации в течение всего жизненного цикла. Исследование проблемы приводит к выводу, что формировать механизм экологического менеджмента следует с учетом специфики строительной деятельности, обеспечивая безопасность на стадии при проектировании объектов, организации строительной площадки, освоении территории застройки, внедрении процессных инноваций в строительстве. В управлении ресурсосбережением кроме инвестиционной стоимости объекта необходимо управлять затратами на эксплуатацию объекта, которые составляют 75 % затрат владения объектом. Принципы экологической эффективности должны находить отражение в показателях оценки инвестиционных проектов. Ответственное с позиций экологии инвестирование может стать одним из трендов реализации национальных проектов, поскольку цели национальных проектов соответствуют концепции устойчивого развития и сбалансированности экономических, социальных и экологических факторов. Выявлены барьеры препятствий ESG-инвестированию в отечественной экономике, в частности недооценка влияния названных факторов на долгосрочные финансовые показатели самих организаций. Для организации системы экологического менеджмента в строительных организациях необходимо формирование системы показателей (индикаторов устойчивости), наличие которой позволит моделировать экологический профиль организации. Экологический профиль позволяет установить баланс внешних запросов и реальных возможностей самой организации. Это требует не только наличия сбалансированной системы экологических показателей организации, но и эталонных значений показателей, обеспечивающих организации повышение конкурентоспособности на рынке подрядных работ.
Pedagogical Competence of Civic Education Teacher in 21st Century: A Systematic Literature Review
Authors: Kabatiah Maryatun , Batubara Abdinur , Ramadhan Taufiq , Rachman Fazli 
Published: October 2024

AbstractThe objective of this study is to ascertain the standards for pedagogical proficiency among civic education teacher in the 21st century, as well as to identify approaches for enhancing their competency. The research method chosen is the Systematic Literature Review (SLR), which uses data from international and national journal articles. The findings indicate that (1) the essential competencies that Civic Education Teachers in the 21st century must possess include life and career skills, encompassing self-regulation, social interaction, and a culture of leadership, productivity, and responsibility; (2) The acquisition of learning and innovation skills, encompassing critical thinking, problem-solving abilities, effective communication, and collaborative engagement in creative endeavors and information sharing; (3) The acquisition of skills in information media and technology, encompassing both information technology and media abilities, is of paramount importance. Teachers must have a comprehensive understanding of information literacy, media literacy, and ICT literacy. Digital pedagogy is a strategy to improve the competence of 21st-century PPKn teachers. Digital pedagogy presents not only digital learning but also digital ethics in utilizing digital resources or learning media.---------------------------------------Abstrak Penelitian menelaah standar kemahiran pedagogi di kalangan guru PPKn pada abad ke-21, serta mengidentifikasi pendekatan untuk meningkatkan kompetensi mereka. Metode penelitian yang dipilih adalah Systematic Literature Review (SLR) dengan sumber data terdiri dari gabungan artikel jurnal internasional dan nasional. Temuan menunjukkan bahwa: (1) kompetensi esensial yang harus dimiliki guru di abad 21 meliputi keterampilan hidup dan karir, meliputi pengaturan diri, interaksi sosial, dan budaya kepemimpinan, produktivitas, dan tanggung jawab, (2) perolehan keterampilan belajar dan inovasi, yang mencakup pemikiran kritis, kemampuan memecahkan masalah, komunikasi efektif, dan keterlibatan kolaboratif dalam upaya kreatif dan berbagi informasi, (3) perolehan keterampilan dalam media dan teknologi informasi, yang mencakup kemampuan teknologi informasi dan media, adalah hal yang sangat penting. Urgen bagi guru untuk memiliki pemahaman komprehensif tentang literasi informasi, literasi media, dan literasi TIK. Pedagogi digital hadir sebagai strategi upaya peningkatan kompetensi guru PPKn abad 21. Pedagogi digital tidak hanya menghadirkan pembelajaran digital, tetapi juga etika digital dalam menamfaatkan sumber daya atau sebagai media pembelajaran digital.