bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surrogate‐based optimization of cordon toll levels in congested traffic networks
Authors: Ekström Joakim , Kristoffersson Ida , Quttineh Nils‐Hassan 
Published: May 2016

SummaryThe benefit, in terms of social surplus, from introducing congestion charging schemes in urban networks is depending on the design of the charging scheme. The literature on optimal design of congestion pricing schemes is to a large extent based on static traffic assignment, which is known for its deficiency in correctly predict travel times in networks with severe congestion. Dynamic traffic assignment can better predict travel times in a road network, but are more computational expensive. Thus, previously developed methods for the static case cannot be applied straightforward. Surrogate‐based optimization is commonly used for optimization problems with expensive‐to‐evaluate objective functions. In this paper, we evaluate the performance of a surrogate‐based optimization method, when the number of pricing schemes, which we can afford to evaluate (because of the computational time), are limited to between 20 and 40. A static traffic assignment model of Stockholm is used for evaluating a large number of different configurations of the surrogate‐based optimization method. Final evaluation is performed with the dynamic traffic assignment tool VisumDUE, coupled with the demand model Regent, for a Stockholm network including 1240 demand zones and 17 000 links. Our results show that the surrogate‐based optimization method can indeed be used for designing a congestion charging scheme, which return a high social surplus. Copyright © 2016 John Wiley & Sons, Ltd.
Identification of a distinct subpopulation of fibroblasts from murine dermis: CD73−CD105+ as potential marker of dermal fibroblasts subset with multipotency
Authors: Lee Seung Bum , Shim Sehwan , Kim Min‐Jung , Shin Hye‐Yun , Jang Won‐Suk , Lee Sun‐Joo , Jin Young‐Woo , Lee Seung‐Sook , Park Sunhoo 
Published: May 2016

AbstractSkin dermis includes various types of multipotent stromal cells (MSCs) and a subpopulation of dermal fibroblasts that exhibit the ability to differentiate. However, characterization of this dermal fibroblast subtype remains less understood. In this study, we isolated dermal cells from the skin of newborn C57/B6 mice and investigated their characteristics. Isolated murine dermal cells exhibited a fibroblast phenotype as judged by accepted criteria including a lack of MSC‐related antigens and the differentiation potential of MSCs, and the positive expression of fibroblast markers. A comparative analysis demonstrated that CD73−CD105+ but not CD73− CD105− dermal fibroblasts exhibited some of the functional properties of MSCs. Furthermore, the multipotent phenotype of CD73−CD105+ cells was diminished by treatment of CD105 siRNA and shRNA, indicating that CD105 expression was critical for the retention of differentiation potential of those cells. Overall, these results suggest that CD73−CD105+ cells are a distinct subset of dermal fibroblasts with multipotency and that their surface antigens could help to classify this subpopulation. These cells may contribute to the regeneration of damaged tissue.
Electrochemical Behavior of Gold–Silver Alloy Nanoparticles
Authors: Plowman Blake J. , Sidhureddy Boopathi , Sokolov Stanislav V. , Young Neil P. , Chen Aicheng , Compton Richard G. 
Published: May 2016

AbstractWe report the voltammetry of alloy nanoparticles by using cyclic voltammetry to study gold–silver alloy nanoparticles. Through careful comparison with the response of pure gold nanoparticles, pure silver nanoparticles, and their mixture, the contrasting electrochemical behavior of the alloy nanoparticles is established, providing insights into the electrochemical stability of gold–silver alloy nanoparticles in chloride‐containing media.
Synchrotron X‐ray Tomographic Study of a Silicon Electrode Before and After Discharge and the Effect of Cavities on Particle Fracturing
Authors: Zielke Lukas , Sun Fu , Markötter Henning , Hilger André , Moroni Riko , Zengerle Roland , Thiele Simon , Banhart John , Manke Ingo 
Published: May 2016

AbstractSilicon (Si) is proposed to be one of the most promising anode materials for next‐generation lithium‐ion batteries, but unsatisfactory discharge capacity and inevitable performance deterioration prevent their commercialisation. In situ synchrotron X‐ray tomography is applied to a Si‐composite electrode‐based battery in its pristine and first discharged state and the degradation of the electron‐ and/or ion‐conducting network, as well as degradation of Si particles, is quantitatively investigated. Thus, this study is complementary to previous X‐ray tomographic studies focusing on Si particles only. On the electrode level, the Si particles located in the central part of the electrode primarily experience crack formation; on the particle level, lithiation behaviour is heterogeneous and cavities are formed during electrode preparation and battery operation. The correlation between the electrochemical activities of Si particles and their individual contact with the conducting network is investigated and quantified: Si particles will experience lithiation only under the condition that at least 40 % of their surface is electrically and ionically connected.
A Naphthalimide‐Based Cd2+ Fluorescent Probe with Carbamoylmethyl Groups Working as Chelators and PET‐Promoters under Neutral Conditions
Authors: Tsukamoto Koji , Shimabukuro Shota , Mabuchi Miyuki , Maeda Hatsuo 
Published: May 2016

AbstractWe have developed a novel naphthalimide‐based Cd2+ fluorescent probe (1), featuring almost no background response, high sensitivity and selectivity toward Cd2+ through its high association constant [K=(2.10±0.423)×106], and a practical working pH range. Membrane‐permeability was conferred on 1 by replacing the imide and amide substituents with n‐butyl groups, and hence the derivative (4) has found practical utility on fluorescent imaging of Cd2+ in HeLa cells. Comparison of fluorescent properties between various compounds derived from 1 has demonstrated that the carbamoylmethyl groups in 1 function not only as Cd2+ chelators but also as promoters for photoinduced electron transfer (PET) by lowering the basicity of the two tertiary amino groups. As a result, 1 and 4 exhibited highly practical performance as Cd2+ probes under neutral conditions.
Double Pancake Versus Long Chalcogen–Chalcogen Bonds in Six‐Membered C,N,S‐Heterocycles
Authors: Haberhauer Gebhard , Gleiter Rolf 
Published: May 2016

AbstractThe double “pancake” bonding in the dimers of the six‐membered heterocycles 1,3‐dithia‐2,4,6‐triazine (4) and 1,3‐dithia‐2,4‐diazine (16) were investigated by means of high‐level quantum chemical calculations (B3LYP and CCSD(T)). It was found that the S–S dimers, 20 a and 27, are not the most stable isomers, but the dimers showing short S−N (21 a) and S−C (25, 28) bonds. An investigation of the 5‐phenyl‐1,3‐dithia‐2,4,6‐triazine (4 b) yields that the syn dimer with two S−S bonds (2.57 Å) is the most stable one. In this dimer, the phenyl groups are placed on top of each other. The additional dispersion energy of the phenyl rings causes a stabilization of the syn‐S–S (C2v‐like) isomer. As a result, two weak albeit relevant single S−S bonds (2.57 Å) are predicted. These findings contradict the recently published concept of double “pancake” bonding in the dimer 4 b2.
Batch‐ and Continuous‐Flow Aerobic Oxidation of 14‐Hydroxy Opioids to 1,3‐Oxazolidines—A Concise Synthesis of Noroxymorphone
Authors: Gutmann Bernhard , Weigl Ulrich , Cox D. Phillip , Kappe C. Oliver 
Published: May 2016

Abstract14‐Hydroxymorphinone is converted to noroxymorphone, the immediate precursor of important opioid antagonists, such as naltrexone and naloxone, in a three‐step reaction sequence. The initial oxidation of the N‐methyl group in 14‐hydroxymorphinone with in situ generated colloidal palladium(0) as the catalyst and molecular oxygen as the terminal oxidant constitutes the key transformation in this new route. This oxidation results in the formation of an unexpected oxazolidine ring structure. Subsequent hydrolysis of the oxazolidine under reduced pressure followed by hydrogenation in a packed‐bed flow reactor using palladium(0) as the catalyst provides noroxymorphone in high purity and good overall yield. To overcome challenges associated with gas–liquid reactions with molecular oxygen, the key oxidation reaction was translated to a continuous‐flow process.
Copper(I)‐Catalyzed Asymmetric Dearomatization of Indole Acetamides with 3‐Indolylphenyliodonium Salts
Authors: Liu Chuan , Yi Ji‐Cheng , Liang Xiao‐Wei , Xu Ren‐Qi , Dai Li‐Xin , You Shu‐Li 
Published: May 2016

AbstractThe rapid and direct asymmetric synthesis of 3‐(3a‐indolyl)hexahydropyrroloindoline motifs is an extremely important part of the total synthesis of several alkaloid structures. Herein, an intermolecular, asymmetric cascade dearomatization reaction of indole acetamides with 3‐indolylphenyliodonium salts has been developed. This protocol provides a straightforward access to 3‐(3a‐indolyl)hexahydropyrroloindolines bearing an all‐carbon quaternary stereocenter at the C3 position of the indoline ring with high enantioselectivities. The utility of the protocol has been demonstrated by the formal asymmetric synthesis of folicanthine.
ChemInform Abstract: Crystal Structures of Sr(BrO3)2‐ H2O, Ba(BrO3)2‐ H2O, Ba(IO3)2‐H2O, Pb(ClO3)2
Authors: LUTZ H. D. , ALICI E. , BUCHMEIER W. 
Published: May 2016

AbstractH2O, and Pb(BrO3)2 ‐ H2O. ‐ The isostructural title compounds Crystallize in the monoclinic system (C2/c, Z=4) (single Crystal XRD).
ChemInform Abstract: Electrocatalysis in Metal Hydride Electiode. Part 1. Hydrogen Electrode Reaction on Group‐IB and VIII Metals Deposited on Palladium Substrates.
Authors: MACHIDA K. , ENYO M. 
Published: May 2016

AbstractThe hydrogen electrode reactions on thin‐layer Cu, Ag, Au, Ni, Pt and Pd electrodes in 0.5 M H2SO4 and 1.0 M NaOH proceed via a Volmer‐Tafel reaction route and the ratio of the rates of the Volmer and Tafel elementary steps is evaluated.
ChemInform Abstract: Yields of O2(b1Σg+) from Reactions of HO2.
Authors: KEYSER L. F. , CHOO K. Y. , LEU M. T. 
Published: May 2016

AbstractProduction of O2(b1∑g+) has been monitored from several reactions of the HO2 radical (known to play a significant role in atmospheric chemistry) at 300 K using the discharge‐flow‐resonance fluorescence (chemiluminescence) technique.
ChemInform Abstract: The Moving Boat Technique and Practical Studies on the Decomposition of Carbonates.
Authors: RAY H. S. , CHOWDHURY D. D. , CHAKRABORTY S. 
Published: May 2016

AbstractThe novel technique (MBT), which is described in detail, allows to study the decomposition of relatively large samples under rising temp. conditions and a ‐t (a: degree of decomposition) plots for several samples can be generated simultaneously from a single run.
ChemInform Abstract: Oxorhodates of Alkali Metals: β‐LiRhO2.
Authors: HOBBIE K. , HOPPE R. 
Published: May 2016

AbstractBlack cubic single crystals of the novel oxorhodate(III) have been prepared Starting from Li2O, Na2O, and Rh2O3 (Li :Na:Rh = 2.9l :l.45 : l , closed Pd tube, 950°C, 18 d).
ChemInform Abstract: Investigations of Vinylic Azides. Part 5. Cathodic Reduction of Aliphatic Azides and of Azides, Activated by Olefinic and Carbonyl Groups.
Authors: KNITTEL D. 
Published: May 2016

AbstractRetention of one nitrogen of the azide group in most of the products obtained by the reduction of (I), (IV), (VI), or (X) leads to novel amine or stabilized enamine derivatives.
ChemInform Abstract: Selective Cyclization and Pinacolization Directed by Tetraalkylammonium Ions.
Authors: KARIV‐MILLER E. , MAHACHI T. J. 
Published: May 2016

AbstractCyclohexanon (II) und 6‐Hepten‐2‐on (V) werden unter verschiedenen Bedingungen elektrochemisch reduziert, wobei unter Normalbedingungen die Alkohole (I) bzw. (IV), in Gegenwart von oberflächenaktiven Verbindungen wie Dimethylpyrrolidinium‐tetrafluoroborat das Pinakol (III) bzw. das Cyclisierungsprodukt (VI) jeweils in hohen Ausbeuten erhalten werden.
ChemInform Abstract: The Preparation of β‐Fluoro Thioethers.
Authors: PURRINGTON S. T. , CORREA I. D. 
Published: May 2016

AbstractDie Cyclohexene (I) addieren Phenylsulfenylchlorid (II) in Gegenwart von AgF zu den Fluor‐thioethern (III), während aus (Ia) mit KF die Chlorverbindung (IV) erhalten wird.
ChemInform Abstract: Syntheses of 2,6,7‐Triazabicyclo[2.2.2]oct‐2‐ene‐5,8‐diones and 4(3H)‐Pyrimidinones via 1,4‐Dipolar Cycloaddition Reactions of Pyrimidinium‐4‐olates to Nitriles.
Authors: GOTTHARDT H. , BLUM J. 
Published: May 2016

AbstractThe pyrimidinium‐olate (II) which has no substituent in the 2‐position undergoes 1,4‐dipolar cycloaddition reactions with the cyano compounds (Ia) or (Ib) to give the products (III).
ChemInform Abstract: Thermal Cycloaddition of Maleic Anhydride to Cycloheptatriene, 7H‐Benzocycloheptene, and 7H‐Benzocycloheptene‐7,7‐dicarbonitrile.
Authors: LEITICH J. , SPRINTSCHNIK G. 
Published: May 2016

AbstractComparative kinetic ana1ysis‐of the title reactions of (I), (V), or (XI) with the anhydride (II) with exclusion of humidity and acid reveal nearly identical orders of magnitude for the rate constants for the addition to (I) and (XI).
ChemInform Abstract: Stereoselective Formation of cis‐2,3‐Dimethylcyclopropanone Hemiacetals from 2‐Halo‐3‐pentanones. [4 + 3]Cycloadditions with Conjugated Diene Systems.
Authors: FOEHLISCH B. + , GEHRLACH E. , STEZOWSKI J. J. , KOLLAT P. , MARTIN E. , GOTTSTEIN W. 
Published: May 2016

AbstractThe halopentanones (Ia) or (Ib) react in the alcohols (II) with the corresponding alkoxides in a highly stereoselective manner to give the hemiacetals (IIIa)‐(IIIc) [X‐ray 28 analysis of the derivative (IIId) from (IIIa): P21/c; Z = 8].
ChemInform Abstract: α‐Ketodicarboxylic Acid Chloride Imide Chlorides in the Synthesis of Heterocycles. Part 2. New Condensed and Spiro Rings.
Authors: CAPUANO L. , WAMPRECHT C. 
Published: May 2016

AbstractThe pyrrolidinedione (I) and the naphthalenediones (XI) afford a series of condensed heterocycles by cyclocondensation, by [4 + 2] cycloaddition or by l′,3‐dipolar cycloaddition.
ChemInform Abstract: Enantioselective N‐Sulfinyl Dienophile Diels‐Alder Cycloadditions.
Authors: REMISZEWSKI S. W. , YANG J. , WEINREB S. M. 
Published: May 2016

AbstractAus den optisch aktiven Alkoholen (Ia) und (IVa) werden über die Carbaminate (Ib) bzw. (IVb) die N‐Sul?nyl‐amide (Ic) bzw. (IVc) hergestellt und dann mit 1,3‐Cyclohexadien (II) umgesetzt, wobei in Gegenwart von Titantetrachlorid fast sterisch einheitliche Diels‐Alder‐ Addukte (III) bzw. (V) erhalten werden.
ChemInform Abstract: Syntheses and Properties of 1,3‐Dialkoxy‐2‐azapropenylium Salts.
Authors: WUERTHWEIN E.‐U. + , KUPFER R. 
Published: May 2016

AbstractThe reaction of the N‐acylimidates (II) with the oxoniuin salts (I) leads to alkylation at the oxygen of the acyl group of (II) [‐+ (III)].
ChemInform Abstract: Trifluoromethyl Group Induced Highly Stereoselective Synthesis of α‐Hydroxy Carbonyl Compounds.
Authors: MORIZAWA Y. , YASUDA A. , UCHIDA K. 
Published: May 2016

Abstract3‐Trif1uormethyl‐buttersäureester (I) wird nach Metallierung mit Molybdänperoxid spezifisch zum Hydroxyester (II) oxidiert; es entstehen nur geringe Anteile an (III), das jedoch aus dem Gemisch aus (II) und (III) nach Oxidation zum Keton (X) und dessen Boranat‐Reduktion zugänglich ist.
ChemInform Abstract: Studies of Hypolipidemic Agents. Part 1. Syntheses and Hypolipidemic Activities of 1‐Substituted 2‐Alkanone Derivatives.
Authors: OGAWA K. , TERADA T. , MURANAKA Y. , HAMAKAWA T. , HASHIMOTO S. , FUJII S. 
Published: May 2016

AbstractDie α‐Chlorketone (III) werden auf 2 verschiedenen Wegen, ausgehend von Epichlorhydrin (I) oder von den Säurechloriden (IV), über die Diazoketone (V) hergestellt.
ChemInform Abstract: PdCl2(MeCN)2‐Catalyzed Carbonylation of Diethylamine with Carbon Dioxide: Selective Synthesis of Tetraethylurea and Diethylformamide.
Authors: MORIMOTO Y. , FUJIWARA Y. , TANIGUCHI H. , HORI Y. , NAGANO Y. 
Published: May 2016

AbstractDiethylamin (I) liefert mit Kohlendioxid in Gegenwart von Pd‐Katalysatoren Tetraethylharnstoff (II) und Diethylformamid (III), wobei in Acetonitril, Tetrachlorkohlenstoff und einem Zusatz von Triphenylphosphin überwiegend der Harnstoff (II), mit Methylcellosolve und Natriumformiat überwiegend das Amid (III) erhalten werden kann.
ChemInform Abstract: Reaction of Fluoroalkenes with the SF4 ‐ HF ‐ S2Cl2 System.
Authors: MURATOV N. N. , MOKHAMED N. M. , KUNSHENKO B. V. , ALEKSEEVA L. A. , YAGUPOL'SKII L. M. 
Published: May 2016

AbstractThe reactions of the trifluoropropene (I), the dichlorodifluoroethene (III) and the chlorotrifluoroethene (VII) with the title system in the absence or in the presence of Sare studied.
ChemInform Abstract: Synthesis and Properties of Fluoronitroalcohols. Part 5. 1,5‐Difluoro‐ 1,1,5,5‐tetranitropentanol.
Authors: FADEEV M. A. , ORESHKO G. V. , EREMENKO L. T. 
Published: May 2016

AbstractDie Tetranitroalkanole (II) werden durch Reduktion aus den entsprechenden Ketonen (I) erhalten.
ChemInform Abstract: Use of Anion Exchange Resin in the Synthesis of Aryloxyacetic Acid Esters.
Authors: BANDGAR B. P. , JAGDALE M. H. , MANE R. B. , SALUNKHE M. M. 
Published: May 2016

AbstractThe nucleophilic polymer‐supported reagent (I) is obtained by reaction of Amberlite IRA‐400 (chloride form) with the sodium salt of aryloxyacetic acid.
ChemInform Abstract: One‐Flask Synthesis of Sulfides from Alcohols and Alkyl Halides Using Benzoxazoline‐2‐thione.
Authors: TAKEUCHI Y. , SAKAGAWA K. , KUBO M. , YAMATO M. 
Published: May 2016

AbstractEin Eintopfverfahren zur Herstellung von Sulfiden (II) aus Alkylhalogeniden und Alkoholen mit Benzoxazolin‐2‐thion als Hilfsreagens.
ChemInform Abstract: A Formal Total Synthesis of Aklavinone via a Blocked Anthraquinone Tautomer.
Authors: KRAUS G. A. , WALLING J. A. 
Published: May 2016

AbstractAus den beiden Naphthochinonen (I) werden die Phenylthio‐cyanide (II) hergestellt und mit dem Butadien (III) in Addukte übergeführt, die nach Jones zu (IV) oxidiert und dann in Zwischenstufen (V) übergeführt werden können.
ChemInform Abstract: A New Approach to the Efficient Indole Synthesis by Allene Intramolecular Cycloaddition.
Authors: HAYAKAWA K. , YASUKOUCHI T. , KANEMATSU K. 
Published: May 2016

AbstractAus den Acroleinen (I) und den Amino‐propinen (II) entstehen die Diene (IV), die mit Formaldehyd/Diisopropylamin und CuBr zu den Allenen (V) führen.
ChemInform Abstract: Synthesis of 3‐Substituted lndoles via N‐Acylindolium Ions.
Authors: COMINS D. L. , STROUD E. D. 
Published: May 2016

AbstractAus dem Indol‐3‐aldehyd (I) erhält man mit Grignard‐Verbindungen (II) die Addukte (III), die mit Triethylsilan zu den 3‐Alkyl‐indolen (IV) reduziert werden.
ChemInform Abstract: Reactions of Carbohydrates with Tetracyanoethylene in Anhydrous Hydrogen Fluoride.
Authors: KOHLA M. , KLEMER A. , MATTES R. , LEIMKUEHLER M. + 
Published: May 2016

AbstractThe carbohydrates (I), (V), (VIII) and (XI) are treated following method A) which furnishes the heterocyclic products shown in the scheme.
ChemInform Abstract: Synthesis of Fatty 2‐Oxazolidones from Epoxy Fatty Acids.
Authors: FAROOQI J. A. 
Published: May 2016

AbstractDie Fettsäureesterepoxide (I) reagieren mit Phenylisocyanat (II) in Gegenwart von Lithiumchlorid in guten Ausbeuten zu den 2‐Oxazolidonen (III).
ChemInform Abstract: Synthesis and Antiinflammatory, Antipyretic, and Analgesic Activities of 5‐(1,2‐Benzisothiazolyl)tetrazoles.
Authors: VICINI P. , AMORETTI L. , BAROCELLI E. , CHIAVARINI M. , IMPICCIATORE M. 
Published: May 2016

AbstractDurch Reaktion der Nitrile (I) bzw. (III) mit Natriumazid erhält man die Tetrazole (II) bzw. (IV).
ChemInform Abstract: The Photoelimination of N‐Nitroso‐N‐acetyl‐α‐amino Acids; a New Synthesis of 1,2,4‐Oxadiazoles.
Authors: CHOW Y. L. , POLO J. S. 
Published: May 2016

AbstractThe acylated N‐nitroso amino acids (II), nitrosopeptide model compounds, are prepared from the precursors (I).
ChemInform Abstract: Synthesis of New 4‐Substituted Xanthotoxins.
Authors: EL‐HAMOULY W. S. , ABOULEZZ A. F. 
Published: May 2016

AbstractIn the endeavour to obtain biologically active derivatives of the known drug xanthotoxin, a series of 4‐substituted compounds is synthesized by reactions of (I) and (V) with various reagents to give (II) and (VI).
ChemInform Abstract: Synthesis and Reactions of Some 4‐Oxo‐4H‐1‐benzopyran‐2‐carboxaldehydes.
Authors: SAMI S. M. , IBRAHIM S. S. , ABDEL‐HALIM A. M. , ALY Y. L. 
Published: May 2016

AbstractThe title compounds (III) are synthesized from the Z‐methylbenzopyrans (I).
ChemInform Abstract: Thermal Fragmentations of Nitrated 8‐Quinolinols.
Authors: SUTTER P. , WEIS C. D. 
Published: May 2016

Abstract8‐Hydroxychinolin sowie die 5‐Nitrosoverbindung (III) werden glatt zu dem 8‐Hydroxy‐5,7‐dinitro‐chinolin (II) nitriert, das auch ausgehend von den Sulfonsäuren (IV) und (VI) erhalten werden kann.
ChemInform Abstract: Studies on Naphthyridines. An Unexpected Product in Hantzsch Pyridine Synthesis.
Authors: BALOGH M. , HERMECZ I. , NARAY‐SZABO G. , SIMON K. , MESZAROS Z. 
Published: May 2016

AbstractThe condensation of ethyl acetoacetate (I) with urotropine (II), under the conditions of the Hantzsch pyridine synthesis, affords the expected pyridine derivative (III) along with the unexpected naphthyridine compound (IV) as a by‐product.
ChemInform Abstract: 1,3‐Dipolar Cycloaddition of Pyridazinium Ylides with Perhalocycloalkenes and Thermal Decomposition of the Adducts.
Authors: OHSAWA A. , WADA I. , IGETA H. 
Published: May 2016

AbstractDie Pyridazinium‐Ylide (I) reagieren in einer 1,3‐dipolaren Cycloaddition mit den Perhalogencyclopropenen (II) bereits bei Raumtemperatur zu den Addukten (III).
ChemInform Abstract: Defined Dimensional Alterations in Enzyme Substrates. General Synthetic Methodology for the Bent Dihydro‐lin‐benzopurines.
Authors: STEVENSON T. M. , KAZMIERCZAK F. , LEONARD N. J. 
Published: May 2016

AbstractDas aus Acetylendicarbonsäure (I) und Butadien (II) erhaltene Anhydrid (III) wird mit Trimethylsilylazid (IV) in das Dihydroisatosäureanhydrid (V) übergeführt, aus dem mit Amidiniumformiat das Dihydro‐chinazolinon (VI) entsteht.
ChemInform Abstract: Selectively 13C‐Enriched 2,4‐Diamino‐5‐(3,4,5‐trimethoxybenzyl)pyrimidine (Trimethoprim) and 2,4‐Diaminopyrimidine.
Authors: SMAL M. , CHEUNG H. T. A. , DAVIES P. E. 
Published: May 2016

AbstractThe selectively labeled derivatives (VII), (XIII) and (XVII) of the antibacterial agent trimethoprim are synthesized for NMR studies of its therapeutic effects.
ChemInform Abstract: Synthesis and Stereochemistry of Carbinolamine Containing Pyrrolo[1,4]benzodiazepines by Reductive Cyclization of N‐(2‐Nitrobenzoyl)pyrrolidine‐2‐carboxaldehydes.
Authors: THURSTON D. E. , LANGLEY D. R. 
Published: May 2016

AbstractDas N‐Nitrobenzoyl‐pyrrolidinylmethanol (I) wird mit PCC zum entsprechenden Aldehyd (II) oxidiert und dieser dann bei der katalytischen Hydrierung zu (III) bzw. (IV) reduktiv cyclisiert.
ChemInform Abstract: Intramolecular Nucleophilic Substitution of Fluorine. A Route to the Synthesis of Polyfluorodibenzo[b,f][1,4]oxazepines.
Authors: PETRENKO N. I. , GERASIMOVA T. N. 
Published: May 2016

AbstractN‐Pentafluorbenzyliden‐ (I) bzw. ‐benzyl‐ Z‐hydroxy‐anilin (IV) cyclisieren unter intramolekularer nucleophiler Substitution eines Fluors zu den Oxazepinen (II) bzw. (III).
ChemInform Abstract: Reaction of Potassium Dialkylthiophosphates with Ethynylbromides in the Presence of Copper(II) Chloride.
Authors: VIKHREVA L. A. , DARISHEVA A. M. , GODOVIKOV N. N. , KABACHNIK M. I. 
Published: May 2016

AbstractKaliumdiethylthiophosphat (I) reagiert mit Kupfer(II)‐chlorid zum isolierbaren Kupfer(I)‐diethylthiophosphat (III) neben dem Disulfid (II).
ChemInform Abstract: Anionic Activation of Diethylphosphite with Potassium Fluoride on Alumina. Synthesis of Functional Phosphonates.
Authors: VILLEMIN D. , RACHA R. 
Published: May 2016

AbstractDiethylphosphit (I) kann ohne Lösungsmittel unter Verwendung von Kaliumfluorid an Aluminiumoxid zu zahlreichen Michael‐ Addukten wie (III), (V), (VII) oder (IX) addiert werden.