bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perilymphatic fistula: a historical overview of publication trends
Authors: Perdomo Dianela , Schoo Wesley W. , Stemme Rachel , Schoo Desi P. , Carey John P. , Ward Bryan K. 
Published: October 2024

BackgroundPerilymph fistula (PLF) can cause symptoms of dizziness, vertigo, and fluctuating hearing. We hypothesized that publications on PLF have decreased in recent years relative to other inner ear disorders with overlapping symptoms.MethodsWe performed a Scopus search using the terms “perilymphatic fistula” OR “perilymph fistula,” limited to original studies or reviews involving human subjects published in English before 2022. We noted the senior author's institution, country affiliation, and publishing journal. The Kendall rank correlation coefficient test was used to analyze the trend of each variable over the past 30 years. Using the same search strategy, we compared these data to those from vestibular neuritis (VN), Meniere's disease (MD), superior semicircular canal dehiscence (SSCD), and benign paroxysmal positional vertigo (BPPV).ResultsSix hundred and ninety-eight PLF publications were returned. The top publishing country was the United States (n = 334), the top publishing journal was the American Journal of Otology/Otology and Neurotology (n = 68), and the top publishing institution was the University of Pittsburgh (n = 15). In the past 30 years (n = 501), there was no trend in the frequency of annual PLF publications (τ = −0.150, p = 0.265). Still there were positive trends in publications on vestibular neuritis (τ = 0.724, p &lt; 0.001), Meniere's disease (τ = 0.587, p &lt; 0.001), superior canal dehiscence syndrome (τ = 0.840, p &lt; 0.001), and benign paroxysmal positional vertigo (τ = 0.882, p &lt; 0.001) 5,398 PLF cases were identified, of which 4,356 specified the etiology; the majority identified an inciting insult (74.8%, n = 3,257).ConclusionsThe absence of diagnostic criteria for PLF may hinder its appeal to researchers as similar syndromes have had diagnostic consensus documents set forth. Given the greater number of cases with inciting insults, efforts to define a diagnostic criterion should focus on this subtype.
The role of mitochondrial DNA copy number in autoimmune disease: a bidirectional two sample mendelian randomization study
Authors: Liu Zhekang , Fu Qingan , Shao Yijia , Duan Xinwang 
Published: October 2024

BackgroundMitochondrial DNA (mtDNA) plays an important role in autoimmune diseases (AD), yet the relationship between mitochondria and autoimmune disease is controversial. This study employed bidirectional Mendelian randomization (MR) to explore the causal relationship between mtDNA copy number and 13 ADs (including ankylosing spondylitis [AS], Crohn’s disease [CD], juvenile rheumatoid arthritis [JRA], polymyalgia rheumatica [PMR], psoriasis [PSO], rheumatoid arthritis [RA], Sjogren’s syndrome [SS], systemic lupus erythematosus [SLE], thyrotoxicosis, type 1 diabetes mellitus [T1DM], ulcerative colitis [UC], and vitiligo)MethodsA two-sample MR analysis was performed to assess the causal relationship between mtDNA copy number and AD. Genome-wide association study (GWAS) for mtDNA copy number were obtained from the UK Biobank (UKBB), while those associated with AD were sourced from the FinnGen Biobank. Inverse variance weighting (IVW) was the primary analysis method, complemented by three sensitivity analyses (MR-Egger, weighted median, weighted mode) to validate the results.ResultsIVW MR analysis identified significant associations between mtDNA copy number and CD (OR=2.51, 95% CI 1.56-4.22, P&lt;0.001), JRA (OR=1.87, 95% CI 1.17-7.65, P=0.022), RA (OR=1.71, 95%CI 1.18-2.47, P=0.004), thyrotoxicosis (OR=0.51, 95% CI0.27-0.96, P=0.038), and T1DM (OR=0.51, 95% CI 0.27-0.96, P=0.038). Sensitivity analyses indicated no horizontal pleiotropy.ConclusionsOur study revealed a potential causal relationship between mtDNA copy number and ADs, indicating that these markers may be relevant in exploring new therapeutic approaches.
Ischemic stroke and sarcopenia have an asymmetric bidirectional relationship based on a two-sample Mendelian randomization study
Authors: Meng Fan-Qiao , Zhang Yu , Bai Xiao-Xin , Kong Fan-Li , Li Feng-E 
Published: October 2024

BackgroundWe investigated the potential relationship between age-related conditions, particularly sarcopenia and ischemic stroke (IS), through a two-sample Mendelian randomization (MR) study.MethodsWe conducted a two-sample bidirectional MR study to investigate the relationship between sarcopenia and stroke. Genetic instruments for sarcopenia were derived from the UK Biobank, while data on IS and its subtypes were obtained from the MEGASTROKE consortium. Inverse variance weighting (IVW) served as the primary analytical method. Additionally, heterogeneity and pleiotropy were assessed to ensure the robustness of the findings.ResultsThe analysis indicates a negative correlation between appendicular lean mass (ALM) and small vessel stroke (SVS; OR = 0.790, 95% CI: 0.703–0.888, p &lt; 0.001), a positive correlation with cardioembolic stroke (CES; OR = 1.165, 95% CI: 1.058–1.284, p = 0.002), and no causal relationship with any ischemic stroke (AIS) or large artery stroke (LAS). Additionally, SVS is negatively associated with right-hand grip strength (OR = 0.639, 95% CI: 0.437–0.934, p = 0.021), while AIS, LAS, and CES do not exhibit a causal relationship with grip strength. Furthermore, no causal relationship was identified between left-hand grip strength, usual walking pace, and IS or its subtypes. MR analysis reveals only a negative association between CES and usual walking pace (OR = 0.989, 95% CI: 0.980–0.998, p = 0.013), with no associations found between other IS subtypes and sarcopenia-related traits.ConclusionThis study demonstrates that a reduction in ALM and right-hand grip strength is associated with SVS, whereas decreased ALM may serve as a protective factor against CES. Conversely, our analysis suggests that CES can impact walking speed. Overall, these findings provide valuable insights into the prevention and treatment of these conditions.
Nutrient profiling assessment of packaged snack foods with nutrition-related claims available on the Indian market
Authors: Bhatnagar Amisha , Choudhary Monika , Kumar Vikas , Singh Vicky , Kaur Prabhdeep 
Published: October 2024

BackgroundFood packaging includes labels with specific nutrient contents to provide consumers with nutritional information. Legislative actions and consumers’ growing interest in nutrition information have increased the disclosure of nutrition information. The study was planned to examine packaged snack foods carrying nutritional claims for nutrition labeling.MethodsThe selected packaged chips were divided into categories based on the primary ingredients mentioned on the nutrition label, such as cereal/pseudocereal-based, millet-based, vegetable-based, and pulses/legume-based chips. Four threshold levels, such as total sugar, sodium, total fat, and saturated fat, were used for categorization.ResultsOut of a total of 23 packaged chips, the corresponding 2, 7, 8, and 13 products had a higher content of sugar, saturated fat, sodium, and total fat than the threshold levels. A significant (p ≤ 0.01) difference was observed in the values of nutrients analyzed through laboratory methods in comparison with the values given on the nutrition label in the majority of the products.ConclusionThe majority of the products belonged to national brands and differed from the nutrition-related information given on the product label in terms of the nutrient content claim.
The link between childhood traumatic events and the continuum of premenstrual disorders
Authors: Standeven Lindsay R. , Bajaj Mira , McEvoy Kathleen , Shirinian Dalar , Voegtline Kristin , Osborne Lauren M. , Payne Jennifer L. , Hantsoo Liisa 
Published: October 2024

BackgroundPremenstrual Syndrome (PMS) and Premenstrual Dysphoric Disorder (PMDD), collectively known as Premenstrual Disorders (PMDs), cause significant distress and functional impairment, and premenstrual exacerbation (PME) affects a large proportion of women with psychiatric diagnoses. Childhood trauma is one factor that may contribute to PMD/PME risk. This study examines the relationship between childhood trauma and PMDs, PME, and non-PMD psychiatric illness.MethodsThis study is a secondary analysis of data from a prospective cohort. Participants completed self-assessments on childhood trauma using the Childhood Traumatic Event Scale (CTE-S) and on premenstrual symptoms using the Premenstrual Symptoms Screening Tool (PSST). Psychiatric diagnoses were assessed through structured clinical interviews. Participants were divided into four groups based on their PSST scores and psychiatric illness status: (1) Premenstrual Disorders (PMDs; moderate to severe PMS and PMDD), (2) PME, (3) psychiatric controls (PC; individuals with psychiatric illness but no significant premenstrual symptoms), and (4) healthy controls (HC; individuals with no psychiatric illness and no significant premenstrual symptoms). Statistical analyses, including ANOVA, Tukey’s HSD test, Fisher’s exact test, and logistic regression, were conducted to examine differences among the groups.ResultsData from 391 participants were analyzed. Participants with PME and PC reported a higher quantity and severity of childhood traumatic events compared to HCs (p &lt;.05). There was a weak but significant correlation between childhood trauma and premenstrual symptom burden across all groups (R = .18, p &lt;.001). Within-group analysis revealed moderate correlations between childhood trauma and premenstrual symptoms driven by the PMD group (R = .42, p = .01).ConclusionsThe findings underscore the impact of childhood traumatic events on mental health and premenstrual symptoms and highlight the need for additional research to explore the underlying mechanisms linking childhood trauma to the continuum of premenstrual disorders, to improve the efficacy of trauma-focused interventions for affected individuals.
Construction Education through Virtual Reality: A Game-based Approach for Interior Architecture Students
Authors: Çalışkan Arda 
Published: October 2024

This study investigates a novel method of instructing interior architecture students on building specifics pertaining to walls by utilizing the combination of virtual reality (VR) and game-based learning. The creation and application of a virtual reality game called "VR ConstructED," which aims to improve knowledge of wall construction methods, materials, and design consequences, is the study's focus. This project intends to improve students' understanding of wall-related construction elements and their applicability in real-world circumstances by utilizing the immersive and interactive properties of virtual reality technology in conjunction with gamification methods. Through a case study involving academic staff and students at Bahçeşehir University, the efficacy of this pedagogical strategy will be assessed. Using a mixed-methods approach, the study collects quantitative data from surveys and qualitative data from semi-structured interviews. These questionnaires will evaluate the academic performance, contentment, and VR game participation of the students. The main goal is to clarify the advantages and difficulties of using virtual VR to teach construction features, such walls, so that curriculum designers and teachers may make informed decisions. Additionally, by illustrating how gamification and the integration of VR technology may greatly improve student engagement and academic achievement, this study hopes to contribute to the larger area of design education. The results of this study are anticipated to add to the body of knowledge in architectural education and stimulate more research into specific VR applications for design pedagogy.
The Impact of Digital Technologies On Manufacturing SMEs
Authors: Sabog Aloysius 
Published: October 2024

Businesses' ecosystems are ever-changing. In this highly competitive era, manufacturing Small-Medium Enterprises (SMEs) are gradually transforming their business operations with state-of-the-art digital technology. This study has established how digital technologies, such as big data analytics, the Internet of Things, and chatbots technologies, affect the business performance of manufacturing SMEs. However, the business performance of manufacturing SMEs is greatly impacted by digital technologies. The purpose of this research is to investigate how digital technologies affect manufacturing SMEs in emerging nations. The goal of digital technology influence is to boost manufacturing SME productivity. In order to find pertinent materials on the topic, this study's technique, which focuses on document analysis, is qualitative. Nineteen empirical papers were used in arriving at the objective of the study through the database of Web of Science, Google Scholar, and Scopus through keyword search. It was discovered that digital technologies significantly enhance the business performance of manufacturing SMEs. The current study has provided new directions, insights and structure for future studies since there is little research on digital technology on manufacturing SMEs. Additionally, the research will assist leaders in their efforts to defend the expenditure of funds on the construction of technology infrastructure for their organizations.
Интракапсулярная и экстракапсулярная коблационная тонзиллэктомия
Authors: Станишевский Р.О. , Теплов А.В. , Кулинич А.И. , Станишевский Н.Р. 
Published: October 2024

Цель. Оценить кровопотерю, болевой синдром и безопасность применения холодной плазмы при удалении небных миндалин интракапсулярно и экстракапсулярно. Материалы и методы. Объектом исследования стали 58 пациентов с диагнозом «хронический тонзиллит, декомпенсированная форма». Пациенты были разделены на 2 группы по 29 человек в каждой. В 1-й группе выполнялась интракапсулярная коблационная тонзиллэктомия, во 2-й – экстракапсулярная коблационная тонзиллэктомия. Интраоперационно оценивались объем кровопотери и время, затраченное на операцию. В течение 10 дней регистрировались случаи ранних и отсроченных кровотечений и уровень боли. Результаты. При проведении коблационной тонзиллэктомии как интракапсулярно, так и экстракапсулярно объем интраоперационных кровотечений составил v 1,6 мл в первой группе и v 2,1 мл во второй группе; время, затраченное на операцию, при интракапсулярной тонзиллэктомии составило t 24,7 мин., при экстракапсулярной t – 4,3 мин. Заключение. Боль в послеоперационном периоде была меньше у пациентов, которым небные миндалины были удалены интракапсулярно. Время, затраченное на оперативное лечение, больше при интракапсулярном методе ввиду более деликатного удаления ткани.
Purpose. To assess blood loss, pain and the safety of using cold plasma when removing palatine tonsils intracapsularly and extracapsularly. Materials and methods. The subjects of the study were 58 patients diagnosed with chronic tonsillitis, decompensated form. The patients were divided into 2 groups of 29 people each. In the 1st group, intracapsular coblation tonsillectomy was performed, in the 2nd group, extracapsular coblation tonsillectomy. The amount of blood loss and the time spent on surgery were assessed intraoperatively. Incidents of early and delayed bleeding and pain levels were recorded over a 10-day period. Results. When performing coblation tonsillectomy both intracapsularly and extracapsularly, the volume of intraoperative bleeding was v=1.6 ml in the first group and v=2.1 ml in the second group, the time spent on surgery for intracapsular tonsillectomy was t 24.7 minutes, for extracapsular tonsillectomy t – 4.3 min. Conclusion. Pain in the postoperative period was less in patients whose tonsils were removed intracapsularly. The time spent on surgical treatment is longer with the intracapsular method, due to more delicate tissue removal.
الاهتمام الاجتماعي لدى طلبة قسم الارشاد النفسي دراسة مقارنة
Authors: أ.د. نشعة كريم عذاب  
Published: October 2024

يعد طلبة قسم الارشاد النفسي والتوجيه التربوي من اكثر الفئات المهمة ،لها دور فعال في بناء و تطوير المجتمع، في حالة توظيف مهاراتهم و اهتماماتهم الاجتماعية، بشكل ذو فائدة للمجتمع ،فضلا عن توفير وغرس الاولويات الازمه لهم لتقليل اسباب او تغيير تجاهاتهم الى اهتمامات اجتماعية مضرة او عديمة الفائدة لا تعمل على تحسين المجتمع، وتعزيز اهتماماتهم الاجتماعية بشكل مستمرومتابعتها لتطويرها، ولاجل بناء مجتمع راقي وواعي .
يستهدف البحث الحالي التعرف إلى
١: الاهتمام الاجتماعي لدى طلبة قسم الارشاد النفسي والتوجيه التربوي بشكل عام.
٢: دلالة الفروق في الاهتمام الاجتماعي بين الذكور والاناث.
وتحقيقا لأهداف البحث الحالي اختيرت عينة عشوائية من مجتمع البحث طلبة قسم الارشاد النفسي والتوجيه التربوي، بلغت (100) طالب وطالبة موزعة الى (50) طالب و(50) طالبة و قامت الباحثة ببناء مقياس الاهتمام الاجتماعي لدى طلبة قسم الارشاد النفسي تكون المقياس من (26) فقره استنادا على نظرية ادلر، واستخرجت الباحثة الخصائص السايكومترية المتمثلة بالصدق الظاهري ومؤشرات صدق البناء تمييز الفقرات ومعامل ارتباط كل الفقرة بالدرجة الكلية للمقياس والثبات بطريقة اعادة الاختبار، اظهرت انها تقيس المتغير وبعد تطبيق المقياس على عينة البحث تم تفريغ البيانات واستعملت الوسائل الاحصائية الاختبار التائي لعينة واحدة والاختبار التائي لعينتين مستقلتين اظهرت النتائج ان عينة البحث طلبة قسم الارشاد لديهم اهتمام اجتماعي ، وكذلك دلالة الفروق بين الذكور والاناث كانت لصالح الذكور. وفي ضوء النتائج وضعت الباحثة مجموعة من الاستنتاجات و التوصيات و المقترحات لأجراء بحوث مستقبلية
أثر استخدام ميرل تينسون في التحصيل لدى طلاب الخامس الابتدائي في مادة الرياضيات
Authors: ا.م.د. صادق مطشر عليخ  
Published: October 2024

هدف البحث الحالي الى التعرف على اثر استخدام ميرل تينسون في التحصيل لدى طلاب الصف الخامس الابتدائي في ماده الرياضيات البحث واختيرت عينه عشوائيا حيث بلغ عدد العينة 93 تلميذا وتلميذه من تلاميذ الصف الخامس الابتدائي من مدرسه الزهراء ومدرسه الطليعية وتم اعداد اواني الاختبار هي اختبار تحصيلي وعند حساب معامل الثبات وجدت ان قيمته ( ) وبعد استكمال البيانات وحسب النتائج اظهرت انه يوجد فرق ذو دلاله إحصائية بين متوسطي المجموعة التجريبية والمجموعة الضابطة في الاختبار التحصيلي ولصالح المجموعة التجريبية وعلى ضوء ذلك اجرى البحث بعدد من التوصيات والمقترحات
..اسـباب انخفـاض مستوى تحصيل مادة الرياضيات لدى طلبة المرحلة الابتدائية من وجهة نظر المعلمين والمعلمات
Authors: م. تغريد خضير حسن  
Published: October 2024

يهدف البحث والحالي الى التعرف على اسباب وانخفاض التحصيل في الرياضيات ولدى تلاميذ المرحلة والابتدائية من وجهة نظر والمعلمين والمعلمات. وتم إعداد استبانة لقياس وانخفاض مستوى وتحصيل الطلاب في والرياضيات. وتم تطبيق اجراءات والدراسة على وعينة مكونة من 200 فرد. المعلمون والمعلمات يمثلون 80% من المجتمع الأصلي لهذه الدراسة، ويتم تحديدهم من قبل معلمي الرياضيات في المرحلة الابتدائية التابعين للمديرية العامة لتربية الكرخ/ الثالثة. وبعد تحليل والبيانات لمعالجتها إحصائيا أطهرت الدراسة والنتائج والتالية:

قلة اهتمام الوالدين يؤدي إلى... تدني تحصيل الطلاب في المرحلة الابتدائية
يؤدي نقص المعدات والوسائل الحديثة إلى انخفاض تحصيل الطلاب.
تؤثر المشكلات السلوكية على الأداء التحصيلي للطلاب في الرياضيات.
أثر استراتيجية فجوة المعلومات تنمية مهارات والتفاعل الصفي لدى طلبة قسم التربية الفنية
Authors: ا.م. مروج منذر محمد  
Published: October 2024

من اهداف البحث الحالي التعرف على اثر استراتيجية فجوة المعلومات لتنمية مهارات التفاعل الصفي لطلبة قسم التربية الفنية في مادة طرائق التدريس العامة لدى طلبة قسم التربية الفنية وتضمن الفصل الأول مشكلة البحث واهمية البحث وتحديد المصطلحات وتضمن الفصل الثاني الاطار النظري وتضمن استراتيجية فجوة المعلومات وانماط التفاعل الصفي واهميته في التدريس و الدراسات السابقة وفي الفصل الثالث تضمن إجراءات البحث حيث اعتمدت الباحثة التصميم التجريبي المناسب للبحث وتحديد مجتمع البحث واختيار العينة، وضبط المتغيرات وبناء الأداة وصولا الى تطبيق التجربة والوسائل الإحصائية وفي الفصل الرابع توصلت الباحثة الى تفوق طلبة المجموعة التجريبية على المجموعة الضابطة التي درست باستراتيجية فجوة المعلومات والتفاعل الصفي ثم جاءت الاستنتاجات والتوصيات والمقترحات والمصادر.
Correlation of Stature and Hand Dimension Among Medical Students of South Tamil Nadu, India
Authors: R Jeba , N P Monteiro Francis N P Monteiro , A J Austoria , Xavier Arun Pinchu , M Asmi , Infant Raj Dominic Infant Raj 
Published: October 2024

Background & Objectives
Estimation of stature from the incomplete skeletal remains have importance in personal identification in the events of murders, accidents or natural disasters and considered as one of the biggest challenges of forensic science. Objectives: To study the relationship of stature in relation with hand dimensions and to derive a mathematical model to predict the stature from hand dimensions.
Methods
This cross-sectional study was done among 50 medical students studying at a medical college in South Tamilnadu. Age, gender, hand dimensions and height of all the subjects were noted. Pearson correlation was done to find the correlation between hand dimensions and height. Linear regression was used to derive the equations to predict the stature of an individual using various dimensions of hands.
Results
The mean age of the study population was 20.06 ± 1.28 years. Regression equations were derived to predict the stature of an individual with length and breadth of right and left hand. There was statistically significant positive correlation between stature and dimensions of both right and left hand. Linear regression equations were derived to predict the stature of an individual with any of the hand dimensions.
Interpretation & Conclusion
Hand dimensions have statistically significant positive correlation with the stature. The length or breadth of the right or left hand can be used to predict the stature of an individual.
Keywords: Breadth of hand, Height, Identification, Length of hand, Linear regression, Prediction, Stature.
A SPectroscopic Survey of Biased Halos In the Reionization Era (ASPIRE): Broad-line AGN at z = 4−5 Revealed by JWST/NIRCam WFSS
Authors: Lin Xiaojing , Wang Feige , Fan Xiaohui , Cai Zheng , Champagne Jaclyn B. , Sun Fengwu , Volonteri Marta , Yang Jinyi , Hennawi Joseph F. , Bañados Eduardo , Barth Aaron , Eilers Anna-Christina , Farina Emanuele Paolo , Liu Weizhe , Jin Xiangyu , Jun Hyunsung D. , Lupi Alessandro , Kakiichi Koki , Mazzucchelli Chiara , Onoue Masafusa , Pan Zhiwei , Pizzati Elia , Rojas-Ruiz Sofía , Schindler Jan-Torge , Trakhtenbrot Benny , Shen Yue , Trebitsch Maxime , Zhuang Ming-Yang , Endsley Ryan , Meyer Romain A. , Li Zihao , Li Mingyu , Pudoka Maria , Tee Wei Leong , Wu Yunjing , Zhang Haowen 
Published: October 2024

Abstract
Low-luminosity active galactic nuclei (AGNs) with low-mass black holes (BHs) in the early universe are fundamental to understanding the BH growth and their coevolution with the host galaxies. Utilizing JWST NIRCam Wide Field Slitless Spectroscopy, we perform a systematic search for broad-line Hα emitters (BHAEs) at z ≈ 4–5 in 25 fields of the A SPectroscopic survey of biased halos In the Reionization Era (ASPIRE) project, covering a total area of 275 arcmin2. We identify 16 BHAEs with FWHM of the broad components spanning from ∼1000 to 3000 km s−1. Assuming that the broad line widths arise as a result of Doppler broadening around BHs, the implied BH masses range from 107 to 108
M
⊙, with broad Hα-converted bolometric luminosities of 1044.5–1045.5 erg s−1 and Eddington ratios of 0.07–0.47. The spatially extended structure of the F200W stacked image may trace the stellar light from the host galaxies. The Hα luminosity function indicates an increasing AGN fraction toward the higher Hα luminosities. We find possible evidence for clustering of BHAEs: two sources are at the same redshift with a projected separation of 519 kpc; one BHAE appears as a composite system residing in an overdense region with three close companion Hα emitters. Three BHAEs exhibit blueshifted absorption troughs indicative of the presence of high column density gas. We find that the broad-line-selected and photometrically selected BHAE samples exhibit different distributions in the optical continuum slopes, which can be attributed to their different selection methods. The ASPIRE broad-line Hα sample provides a good database for future studies of faint AGN populations at high redshift.