bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pseudo-automatic Determination of Coronal Mass Ejections’ Kinematics in 3D
Authors: Braga Carlos Roberto , Dal Lago Alisson , Echer Ezequiel , Stenborg Guillermo , Souza de Mendonça Rafael Rodrigues 
Published: June 2017

Abstract
Coronal mass ejection (CME) events are among the main drivers of geomagnetic disturbances, and hence play a central role in the Sun–Earth system. Their monitoring and, in particular, the determination of their speed and direction of propagation are key issues for the forecasting of space weather near to Earth. We have implemented a method to track CME events in three dimensions by combining triangulation and tie-pointing analysis with a supervised computer vision algorithm. This novel approach does not rely on any geometric constraint, and eliminates the need for visual identification of the CME boundaries. We applied our method to 17 CME events observed simultaneously by the twin Solar Terrestrial Relations Observatory (STEREO) COR2 coronagraph imagers from 2008 December to 2011 November in order to obtain their 3D kinematical characterization (i.e., the velocity vector) along with their morphological properties. About ten of these events have already been analyzed using other methodologies. In these cases, we carried out a thorough comparison with our results and found that, in spite of the different nature and spatial coverage range of the other methods with respect to CORSET3D, the majority of the results agree. We found, however, that three events exhibited discrepancies in the magnitude of the velocity vector, four in the longitudinal direction of propagation, and in only one case was there a discrepancy in latitude. The discrepancies appeared in those cases where quasi-simultaneous, quasi-co-located events were observed in the coronagraphs’ fields of view.
Joining X-Ray to Lensing: An Accurate Combined Analysis of MACS J0416.1–2403
Authors: Bonamigo M. , Grillo C. , Ettori S. , Caminha G. B. , Rosati P. , Mercurio A. , Annunziatella M. , Balestra I. , Lombardi M. 
Published: June 2017

Abstract
We present a novel approach for a combined analysis of X-ray and gravitational lensing data and apply this technique to the merging galaxy cluster MACS J0416.1–2403. The method exploits the information on the intracluster gas distribution that comes from a fit of the X-ray surface brightness and then includes the hot gas as a fixed mass component in the strong-lensing analysis. With our new technique, we can separate the collisional from the collision-less diffuse mass components, thus obtaining a more accurate reconstruction of the dark matter distribution in the core of a cluster. We introduce an analytical description of the X-ray emission coming from a set of dual pseudo-isothermal elliptical mass distributions, which can be directly used in most lensing softwares. By combining Chandra observations with Hubble Frontier Fields imaging and Multi Unit Spectroscopic Explorer spectroscopy in MACS J0416.1–2403, we measure a projected gas-to-total mass fraction of approximately 10% at 350 kpc from the cluster center. Compared to the results of a more traditional cluster mass model (diffuse halos plus member galaxies), we find a significant difference in the cumulative projected mass profile of the dark matter component and that the dark matter over total mass fraction is almost constant, out to more than 350 kpc. In the coming era of large surveys, these results show the need of multiprobe analyses for detailed dark matter studies in galaxy clusters.
Baroclinic Instability in the Solar Tachocline for Continuous Vertical Profiles of Rotation, Effective Gravity, and Toroidal Field
Authors: Gilman Peter A. 
Published: June 2017

Abstract
We present results from an MHD model for baroclinic instability in the solar tachocline that includes rotation, effective gravity, and toroidal field that vary continuously with height. We solve the perturbation equations using a shooting method. Without toroidal fields but with an effective gravity declining linearly from a maximum at the bottom to much smaller values at the top, we find instability at all latitudes except at the poles, at the equator, and where the vertical rotation gradient vanishes (32.°3) for longitude wavenumbers m from 1 to >10. High latitudes are much more unstable than low latitudes, but both have e-folding times that are much shorter than a sunspot cycle. The higher the m and the steeper the decline in effective gravity, the closer the unstable mode peak to the top boundary, where the energy available to drive instability is greatest. The effect of the toroidal field is always stabilizing, shrinking the latitude ranges of instability as the toroidal field is increased. The larger the toroidal field, the smaller the longitudinal wavenumber of the most unstable disturbance. All latitudes become stable for a toroidal field exceeding about 4 kG. The results imply that baroclinic instability should occur in the tachocline at latitudes where the toroidal field is weak or is changing sign, but not where the field is strong.
Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells
Authors: Borger Jessica G. , Morrison Vicky L. , Filby Andrew , Garcia Celine , Uotila Liisa M. , Simbari Fabio , Fagerholm Susanna C. , Zamoyska Rose 
Published: June 2017

Abstract
TCR stimulation by peptide–MHC complexes on APCs requires precise reorganization of molecules into the area of cellular contact to form an immunological synapse from where T cell signaling is initiated. Caveolin (Cav)1, a widely expressed transmembrane protein, is involved in the regulation of membrane composition, cellular polarity and trafficking, and the organization of signal transduction pathways. The presence of Cav1 protein in T cells was identified only recently, and its function in this context is not well understood. We show that Cav1-knockout CD8 T cells have a reduction in membrane cholesterol and sphingomyelin, and upon TCR triggering they exhibit altered morphology and polarity, with reduced effector function compared with Cav1 wild-type CD8 T cells. In particular, redistribution of the β2 integrin LFA-1 to the immunological synapse is compromised in Cav1-knockout T cells, as is the ability of LFA-1 to form high-avidity interactions with ICAM-1. Our results identify a role for Cav1 in membrane organization and β2 integrin function in primary CD8 T cells.
Ekedahl-Oort Strata for Good Reductions of Shimura Varieties of Hodge Type
Authors: Zhang Chao 
Published: June 2017

AbstractFor a Shimura variety of Hodge type with hyperspecial level structure at a primep, Vasiu and Kisin constructed a smooth integral model (namely the integral canonical model) uniquely determined by a certain extension property. We define and study the Ekedahl-Oort stratifications on the special fibers of those integral canonical models whenp> 2. This generalizes Ekedahl-Oort stratifications defined and studied by Oort on moduli spaces of principally polarized abelian varieties and those defined and studied by Moonen, Wedhorn, and Viehmann on good reductions of Shimura varieties of PEL type. We show that the Ekedahl-Oort strata are parameterized by certain elementswin the Weyl group of the reductive group in the Shimura datum. We prove that the stratum corresponding towis smooth of dimensionl(w) (i.e., the length ofw) if it is non-empty. We also determine the closure of each stratum.
Quantifying uncertainties of permafrost carbon–climate feedbacks
Authors: Burke Eleanor J. , Ekici Altug , Huang Ye , Chadburn Sarah E. , Huntingford Chris , Ciais Philippe , Friedlingstein Pierre , Peng Shushi , Krinner Gerhard 
Published: June 2017

Abstract. The land surface models JULES (Joint UK Land Environment Simulator, two versions) and ORCHIDEE-MICT (Organizing Carbon and Hydrology in Dynamic Ecosystems), each with a revised representation of permafrost carbon, were coupled to the Integrated Model Of Global Effects of climatic aNomalies (IMOGEN) intermediate-complexity climate and ocean carbon uptake model. IMOGEN calculates atmospheric carbon dioxide (CO2) and local monthly surface climate for a given emission scenario with the land–atmosphere CO2 flux exchange from either JULES or ORCHIDEE-MICT. These simulations include feedbacks associated with permafrost carbon changes in a warming world. Both IMOGEN–JULES and IMOGEN–ORCHIDEE-MICT were forced by historical and three alternative future-CO2-emission scenarios. Those simulations were performed for different climate sensitivities and regional climate change patterns based on 22 different Earth system models (ESMs) used for CMIP3 (phase 3 of the Coupled Model Intercomparison Project), allowing us to explore climate uncertainties in the context of permafrost carbon–climate feedbacks. Three future emission scenarios consistent with three representative concentration pathways were used: RCP2.6, RCP4.5 and RCP8.5. Paired simulations with and without frozen carbon processes were required to quantify the impact of the permafrost carbon feedback on climate change. The additional warming from the permafrost carbon feedback is between 0.2 and 12 % of the change in the global mean temperature (ΔT) by the year 2100 and 0.5 and 17 % of ΔT by 2300, with these ranges reflecting differences in land surface models, climate models and emissions pathway. As a percentage of ΔT, the permafrost carbon feedback has a greater impact on the low-emissions scenario (RCP2.6) than on the higher-emissions scenarios, suggesting that permafrost carbon should be taken into account when evaluating scenarios of heavy mitigation and stabilization. Structural differences between the land surface models (particularly the representation of the soil carbon decomposition) are found to be a larger source of uncertainties than differences in the climate response. Inertia in the permafrost carbon system means that the permafrost carbon response depends on the temporal trajectory of warming as well as the absolute amount of warming. We propose a new policy-relevant metric – the frozen carbon residence time (FCRt) in years – that can be derived from these complex land surface models and used to quantify the permafrost carbon response given any pathway of global temperature change.
Testing seismic amplitude source location for fast debris-flow detection at Illgraben, Switzerland
Authors: Walter Fabian , Burtin Arnaud , McArdell Brian W. , Hovius Niels , Weder Bianca , Turowski Jens M. 
Published: June 2017

Abstract. Heavy precipitation can mobilize tens to hundreds of thousands of cubic meters of sediment in steep Alpine torrents in a short time. The resulting debris flows (mixtures of water, sediment and boulders) move downstream with velocities of several meters per second and have a high destruction potential. Warning protocols for affected communities rely on raising awareness about the debris-flow threat, precipitation monitoring and rapid detection methods. The latter, in particular, is a challenge because debris-flow-prone torrents have their catchments in steep and inaccessible terrain, where instrumentation is difficult to install and maintain. Here we test amplitude source location (ASL) as a processing scheme for seismic network data for early warning purposes. We use debris-flow and noise seismograms from the Illgraben catchment, Switzerland, a torrent system which produces several debris-flow events per year. Automatic in situ detection is currently based on geophones mounted on concrete check dams and radar stage sensors suspended above the channel. The ASL approach has the advantage that it uses seismometers, which can be installed at more accessible locations where a stable connection to mobile phone networks is available for data communication. Our ASL processing uses time-averaged ground vibration amplitudes to estimate the location of the debris-flow front. Applied to continuous data streams, inversion of the seismic amplitude decay throughout the network is robust and efficient, requires no manual identification of seismic phase arrivals and eliminates the need for a local seismic velocity model. We apply the ASL technique to a small debris-flow event on 19 July 2011, which was captured with a temporary seismic monitoring network. The processing rapidly detects the debris-flow event half an hour before arrival at the outlet of the torrent and several minutes before detection by the in situ alarm system. An analysis of continuous seismic records furthermore indicates that detectability of Illgraben debris flows of this size is unaffected by changing environmental and anthropogenic seismic noise and that false detections can be greatly reduced with simple processing steps.
Dynamics and style transition of a moderate, Vulcanian-driven eruption at Tungurahua (Ecuador) in February 2014: pyroclastic deposits and hazard considerations
Authors: Romero Jorge Eduardo , Douillet Guilhem Amin , Vallejo Vargas Silvia , Bustillos Jorge , Troncoso Liliana , Díaz Alvarado Juan , Ramón Patricio 
Published: June 2017

Abstract. The ongoing eruptive cycle of Tungurahua volcano (Ecuador) since 1999 has been characterised by over 15 paroxysmal phases interrupted by periods of relative calm. Those phases included one Subplinian as well as several Strombolian and Vulcanian eruptions and they generated tephra fallouts, pyroclastic density currents (PDCs) and lava flows. The 1 February 2014 eruption occurred after 75 days of quiescence and only 2 days of pre-eruptive seismic crisis. Two short-lived Vulcanian explosions marked the onset of the paroxysmal phase, characterised by a 13.4 km eruptive column and the trigger of PDCs. After 40 min of paroxysm, the activity evolved into sporadic Strombolian explosions with discrete ash emissions and continued for several weeks. Both tephra fall and PDCs were studied for their dispersal, sedimentology, volume and eruption source parameters. At large scale, the tephra cloud dispersed toward the SSW. Based on the field data, two dispersal scenarios were developed forming either elliptical isopachs or proximally PDC-influenced isopachs. The minimum bulk tephra volumes are estimated to 4.55 × 106 m3, for an eruption size estimated at volcanic explosivity index (VEI) 2–3. PDCs, although of small volume, descended by nine ravines of the NNW flanks down to the base of the edifice. The 1 February 2014 eruptions show a similar size to the late 1999 and August 2001 events, but with a higher intensity (I 9–10) and shorter duration. The Vulcanian eruptive mechanism is interpreted to be related to a steady magma ascent and the rise in over-pressure in a blocked conduit (plug) and/or a depressurised solidification front. The transition to Strombolian style is well documented from the tephra fall componentry. In any of the interpretative scenarios, the short-lived precursors for such a major event as well as the unusual tephra dispersion pattern urge for renewed hazard considerations at Tungurahua.
Short-Term Outcomes of Open Hip Preservation Surgery for Symptomatic Extraarticular Femoroacetabular Impingement
Authors: Ricciardi Benjamin F. , Fields Kara G. , Wentzel Catherine , Kelly Bryan T. , Sink Ernest L. 
Published: June 2017

Introduction The purposes of this study were to describe: (i) short-term disease-specific patient-reported outcome scores (PROMs); and (ii) factors associated with reoperation or treatment failure in patients undergoing open hip preservation surgery for symptomatic extraarticular FAI. Methods Patients undergoing open hip preservation surgery for symptomatic extraarticular FAI were identified from a prospective, single-centre hip preservation registry (n = 51 patients; median clinical follow-up 24 [range 11-49] months). Hip-specific PROMs were assessed preoperatively, 6 months, and each year subsequently. Patients undergoing reoperation or treatment failure (<10 point improvement in iHOT-33 postoperatively) over the study period were identified. Preoperative associated factors were explored on a univariate basis. Results International Hip Outcome Tool-33 (iHOT-33) improved from 33 (standard deviation [SD] 18) to 62 (26) at most recent follow-up and 76% of patients improved by minimum clinically important difference (MCID). Harris Hip Score improved from 53 (15) to 75 (17) at most recent follow-up and 79% of patients improved by MCID. Hip Outcome Score (HOS) Sport improved from 45 (26) to 66 (28) at most recent follow-up and 60% of patients improved by MCID. Continued improvements in mean follow-up scores were seen from 1 year to 2 years. Overall, 7 patients underwent reoperation and 9 patients failed to improve by MCID. Preoperative HOS Sport was higher in patients experiencing reoperation or treatment failure (58 [SD 19] vs. 40 [SD 27] respectively; p = 0.03). No other associated demographic, physical examination, or radiographic factors were found. Conclusions Open treatment of extraarticular FAI results in short-term improvements in hip-specific PROMs in most patients. Higher HOS Sport scores were associated with reoperation or treatment failure. Longer-term follow-up is necessary to define maximum improvements in this challenging patient population.
Rewired/Remixed: Event for Dismembered Body
Authors: Stelarc  
Published: June 2017

ABSTRACT
Ideas are easy; the difficulty is in actualizing them. Our imagination not only is aided but actually is initiated by our instruments and computational systems. Unexpected information and images irradiate and mutate our desires and necessitate additional external organs. The posthuman and the transhuman are not merely about sci-fi speculation and theorizing possibilities but rather are about physically interrogating the biological status quo and engineering interfaces that short-circuit the body’s present expectations and experiences. Affirming the sensory, cortical, and anatomical architecture of the body in an age of AI-imbued computational systems and precise and powerful instruments and machines is sheer folly. The body at present is a monstrous chimera of biology, technology, and code. But it’s not enough to optimize or enhance bodies that are profoundly obsolete in form and function. It’s not enough to prosthetically patch up bodies. It’s time to redesign. Time for alternate embodiment and distributed agency. Time to surpass circulating, fractal, and phantom flesh. Time for engineering contestable futures. This article is a visual essay with descriptions of a performance expressing these themes and comments on the artist’s experience.
Pragmatic Functions of Ettehkey as a Discourse Marker in Korean Spoken Data
Authors: Chung Hyunsun 
Published: June 2017

ABSTRACT
This study investigates the pragmatic functions of ettehkey, a discourse marker derived from a question word in colloquial Korean. Ettehkey, as an interrogative word that corresponds to how in English, is commonly considered a contracted form of ettehakey, which derives from an interrogative adjective, ettehata. Ettehkey is also used as an indefinite word that refers to a nonspecific referent. Several studies have highlighted discourse-pragmatic aspects of Korean wh-question words as discourse. However, the research on pragmatic features of ettehkey as a discourse marker is scarce. Therefore, the present study examines how ettehkey pragmatically functions in natural conversation, considering this development as a grammaticalization process. The study argues that pragmatic functions of the discourse marker ettehkey can be broadly categorized as a hearer-centered mitigator and a speaker-centered intensifier. As a hearer-centered mitigator, it can be realized as a hedging device in bringing up a new topic, allowing the hearer some freedom in response or mitigating a question's imposition. As a speaker-centered intensifier, ettehkey tends to emphasize the speaker's unexpected or perplexed stance at an interlocutor's (non)verbal action or a topic of conversation. For this study, 50 naturally occurring telephone conversations from the Korean Telephone Conversations Speech Corpus were analyzed.
Cutaneous and Superficial Soft Tissue CD34+ Spindle Cell Proliferation
Authors: Yang Hongyu , Yu Limin 
Published: June 2017

Context.—Cutaneous and superficial soft tissue spindle cell proliferations with CD34 expression represent a unique heterogeneous group of lesions. They can pose diagnostic challenges for unaware pathologists in their daily practice.Objective.—To review selected entities of CD34+ spindle cell proliferations in the skin and superficial soft tissue. The effective diagnostic approaches using clinical, histopathologic, and immunophenotypical findings are discussed within a broad spectrum of differential diagnosis.Data Sources.—All information used in the article is obtained from published literature by PubMed search and Internet-based search engines. The authors' collective experience and real-life examples are also used.Conclusions.—Spindle cell proliferations with CD34 positivity can be worked up to a definitive diagnosis by using clinical, histopathologic, and immunophenotypical findings. Familiarity with these entities helps pathologists make the accurate diagnosis.
Viral kinetics in untreated versus treated acute HIV infection in prospective cohort studies in Thailand
Authors: Ananworanich Jintanat , Eller Leigh Anne , Pinyakorn Suteeraporn , Kroon Eugene , Sriplenchan Somchai , Fletcher James LK , Suttichom Duanghathai , Bryant Christopher , Trichavaroj Rapee , Dawson Peter , Michael Nelson , Phanuphak Nittaya , Robb Merlin L ,   RV217 RV254/SEARCH010 study groups
Published: June 2017

AbstractIntroduction: The extent of viral replication during acute HIV infection (AHI) influences HIV disease progression. However, information comparing viral load (VL) kinetics with and without antiretroviral therapy (ART) in AHI is limited. The knowledge gained could inform preventive strategies aimed at reducing VL during AHI and therapeutic strategies to alter the viral kinetics that may enhance the likelihood of achieving HIV remission.Methods: The analysis utilized VL data captured during the first year of HIV infection from two studies in Thailand: the RV217 study (untreated AHI, 30 participants and 412 visits) and the RV254 study (treated AHI, 235 participants and 2803 visits). Fiebig stages were I/II (HIV RNA+, HIV IgM−) and Fiebig III/IV (HIV IgM+, Western blot‐/indeterminate). Data were modelled utilizing spline effects within a linear mixed model, with a random intercept and slope to allow for between‐subject variability and adjustment for the differences in variability between studies. The number of knots in the quadratic spline basis functions was determined by comparing models with differing numbers of knots via the Akaike Information Criterion. Models were fit using PROC GLIMMIX in SAS v9.3.Results: At enrolment, there were 24 Fiebig I/II and 6 Fiebig III/IV individuals in the untreated group and 137 Fiebig I/II and 98 Fiebig III/IV individuals in the treated group. Overall, the median age was 27.5 years old, most were male (89%), and CRF01_AE was the most common HIV clade (76%). By day 12 (4 days after ART in RV254), the untreated group had a 2.7‐fold higher predicted mean VL level compared to those treated (predicted log VL 6.19 for RV217 and 5.76 for RV254, p = 0.05). These differences increased to 135‐fold by day 30 (predicted log VL 4.89 for RV217 and 2.76 for RV254) and 1148‐fold by day 120 (predicted log VL 4.68 for RV217 and 1.63 for RV254) (p < 0.0001 for both) until both curves were similarly flat at about day 150 (p = 0.17 between days 150 and 160). The VL trajectories were significantly different between Fiebig I/II and Fiebig III/IV participants when comparing the two groups and within the treated group (p < 0.001 for both).Conclusions: Initiating ART in AHI dramatically changed the trajectory of VL very early in the course of infection that could have implications for reducing transmission potential and enhancing responses to future HIV remission strategies. There is an urgency of initiating ART when acute infection is identified. New and inexpensive strategies to engage and test individuals at high risk for HIV as well as immediate treatment access will be needed to improve the treatment of acute infection globally.Clinical Trial Number: NCT00796146 and NCT00796263