bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospective, randomized, evaluator‐blinded study of the long pulse 532‐nm KTP laser alone or in combination with the long pulse 1064‐nm Nd: YAG laser on facial rejuvenation in Asian skin
Authors: Negishi Kei , Tanaka Shiho , Tobita Saori 
Published: September 2016

Background and ObjectiveHyperpigmentation is a common concern in Asian patients. Few published studies address overall skin rejuvenation in this group using long‐pulse (LP) laser to target pigmentation and stimulate dermal remodeling. The LP KTP 532‐nm laser (LP 532‐nm) is used primarily to remove epidermal lesions, while the LP Nd: YAG 1064‐nm laser (LP 1064‐nm) is used to stimulate dermal remodeling in Asian patients with varying efficacy. The LP 532‐nm used alone and in combination with LP 1064‐nm to reduce pigmentation and rejuvenate skin was previously evaluated in lighter skin, but not in Asian skin. We evaluated the safety and effectiveness of using LP 532‐nm for overall photorejuvenation, with and without LP 1064‐nm.Study Design/Materials and MethodsFour treatments were administered at 3‐week intervals to 22 Japanese females with photodamaged facial skin and bilateral solar lentigines. A direct split‐face treatment with LP 532‐nm was used on the full‐face, and an additional, randomized LP 1064 treatment was administered to one‐half of the face. Patients were not fully aware which side of the face was treated with which treatment. Results were evaluated at each treatment, and at 1‐ and 3‐month follow‐up visits.ResultsScoring of a modified pigment severity index (mPSI) and measurement of the melanin index (MI) showed that facial skin treated with LP 532‐nm alone and in combination with LP 1064‐nm resulted in improvement at the 1‐ and 3‐month follow‐up (P < 0.001), but there was no difference between the two sides of the face. Notably, the three dimensional analysis of skin surface showed improvements for the dual‐wavelength treatments with significant differences between the two sides (P = 0.003). Most patients reported moderate improvement and were extremely satisfied or satisfied with the outcome. Adverse events were minor and rare.ConclusionsPigment‐related skin rejuvenation using LP 532‐nm appears to be safe and effective for Asian skin. The addition of LP 1064‐nm showed no clinical difference but the subtle difference was detected by the 3D analyzing device. Lasers Surg. Med. 48:844–851, 2016. © 2016 Wiley Periodicals, Inc.
Sensate hypothenar perforator free flap for resurfacing large volar surface defect of the digit
Authors: Seo Bommie Florence , Kwon Byung Yeun , Han Hyun Ho 
Published: September 2016

AbstractIn this report we present a case of large sized volar surface defect of a digit reconstructed by hypothenar perforator free flap coverage. A 57‐year‐old male patient presented with a 5 × 2 cm sized avulsive injury on his left little finger involving near total loss of the volar surface. The perforator arteries of the hypothenar area were identified around 5–15% on the x‐axis and 25–50% on the y‐axis (y‐axis: a line from the pisiform base to the metacarpophalangeal joint, x‐axis: a line perpendicular to the y‐axis.) The hypothenar free flap was designed centered on the anticipated location of the perforator artery. Upon dissection, the perforator artery was found as predicted and a superficial palmar vein was saved for venous drainage. In addition, a neighboring cutaneous branch of the ulnar nerve was also saved. The flap survived with satisfactory flap contour, durability, skin color and texture. Five months of follow‐up showed acceptable range of motion for joints of the affected digit and nearly full range of motion for the hand. The sensate hypothenar perforator free flap could be considered as a useful surgical option for large sized volar side defects of finger.
Peroneal perforator‐based peroneus longus tendon and sural neurofasciocutaneous composite flap transfer for a large soft‐tissue defect of the forearm: A case report
Authors: Hayashida Kenji , Saijo Hiroto , Fujioka Masaki 
Published: September 2016

AbstractWe describe the use of a composite flap composed of a sural neurofasciocutaneous flap and a vascularized peroneus longus tendon for the reconstruction of severe composite forearm tissue defects in a patient. A 43‐year‐old man had his left arm caught in a conveyor belt resulting in a large soft‐tissue defect of 18 × 11 cm over the dorsum forearm. The extensor carpi radialis, superficial radial nerve, and radial artery were severely damaged. A free neurofasciocutaneous composite flap measuring 16 × 11 cm was outlined on the patient's left lower leg to allow simultaneous skin, tendon, nerve, and artery reconstruction. The flap, which included the peroneus longus tendon, was elevated on the subfascial plane. After the flap was transferred to the recipient site, the peroneal artery was anastomosed to the radial artery in a flow‐through manner. The vascularized tendon graft with 15 cm in length was used to reconstruct the extensor carpi radialis longus tendon defect using an interlacing suture technique. As the skin paddle of the sural neurofasciocutaneous flap and the vascularized peroneus longus tendon graft were linked by the perforator and minimal fascial tissue, the skin paddle was able to rotate and slide with comparative ease. The flap survived completely without any complications. The length of follow‐up was 12 months and was uneventful. Range of motion of his left wrist joint was slightly limited to 75 degrees. This novel composite flap may be useful for reconstructing long tendon defects associated with extensive forearm soft tissue defects.
Companion planting with white yarrow or with feverfew for squash bug, Anasa tristis (Hemiptera: Coreidae), management on summer squash
Authors: Kahn Brian A , Rebek Eric J , Brandenberger Lynn P , Reed Keith , Payton Mark E 
Published: September 2016

AbstractBACKGROUNDThe squash bug, Anasa tristis (De Geer), is a major insect pest of cucurbits. Control of squash bugs with insecticidal chemicals is difficult to achieve. We investigated the potential of companion planting with white yarrow (Achillea millefolium L.) or feverfew [Tanacetum parthenium (L.) Sch. Bip.] for squash bug management in field plantings of summer squash (Cucurbita pepo L.).RESULTSCompanion planting with white yarrow had few effects. Companion planting with feverfew tended to reduce squash bug populations, but results often were not statistically significant (P ≥ 0.05). Early‐season ventilated row covers (without herbs) neither reduced squash bug populations nor increased squash yields. Herbs reduced marketable squash yields compared with the control only once out of seven experiments.CONCLUSIONThe tested companion planting strategies inconsistently affected squash bug populations on summer squash. Therefore, these strategies are not recommended to commercial producers. © 2016 Society of Chemical Industry
Discovery of the aryl heterocyclic amine insecticides: synthesis, insecticidal activity, field results, mode of action and bioavailability of a leading field candidate
Authors: Dent William H , Pobanz Mark A , Geng Chaoxian , Sparks Thomas C , Watson Gerald B , Letherer Theodore J , Beavers Kenneth W , Young Cathy D , Adelfinskaya Yelena A , Ross Ronald R , Whiteker Greg , Renga James 
Published: September 2016

AbstractBACKGROUNDγ‐Amino butyric acid (GABA) antagonists are proven targets for control of lepidopteran and other pests. New heterocyclic compounds with high insecticidal activity were discovered using a competitive‐intelligence‐inspired scaffold‐hopping approach to generate analogs of fipronil, a known GABA antagonist. These novel aryl heterocyclic amines (AHAs) displayed broad‐spectrum activity on a number of chewing insect pests.RESULTSThrough >370 modifications of the core AHA structure, a 7‐pyrazolopyridine lead molecule was found to exhibit much improved activity on a number of insect pests. In field trial studies, its performance was 2–4 times lower than commercial standards and also appeared to be species dependent, with good activity seen for larvae of Spodoptera exigua, but inactivity on larvae of Trichoplusia ni.CONCLUSIONAn extensive investigational biology effort demonstrated that these AHA analogs appear to have multiple modes of action, including GABA receptor antagonism and mitopotential or uncoupler activity. The limited capability in larvae of T. ni to convert the lead molecule to its associated open form correlates with the low toxicity of the lead molecule in this species. This work has provided information that could aid investigations of novel GABA antagonists. © 2016 Society of Chemical Industry
Active saponins from root of Pueraria peduncularis (Grah. ex Benth.) Benth. and their molluscicidal effects on Pomacea canaliculata
Authors: Yang ChunPing , Zhang Min , Lei Bo , Gong GuoShu , Yue GuiZhou , Chang XiaoLi , Sun XiaoFang , Tian Yue , Chen HuaBao 
Published: September 2016

AbstractBACKGROUNDPueraria peduncularis (Grah. ex Benth.) Benth., which belongs to the Leguminosae family, exhibits resistance to many crop pests in agricultural production. Pomacea canaliculata is an important invasive snail in rice fields and causes severe yield losses. To evaluate the toxicity of P. peduncularis to P. canaliculata, in this study the molluscicidal activity of root extracts of P. peduncularis was tested against P. canaliculata; the active compounds were isolated, and the structures of these compounds were analysed using nuclear magnetic resonance (NMR) analysis and mass spectral analysis.RESULTSOur results showed that the molluscicidal activity of the root crude extract differed between P. canaliculata with different shell diameters after treatment for 72 h. The median lethal concentration (LC50) was 5.511 mg L−1 against snails of 1.5 ± 0.2 cm diameter and 12.383 mg L−1 against snails of 2.5 ± 0.2 cm diameter. Furthermore, two active ingredients isolated from root methanol extracts were identified as pedunsaponin A and pedunsaponin C. Both pedunsaponin A and pedunsaponin C showed strong molluscicidal activities, with LC50 values of 3.893 and 4.252 mg L−1, respectively, against snails with shell diameters of 1.5 ± 0.2 cm after treatment for 72 h.CONCLUSIONPueraria peduncularis extracts exhibit high molluscicidal activity and have great potential value for exploring a molluscicide to control Pomacea canaliculata. © 2016 Society of Chemical Industry
Iron pnictide thin films: Synthesis and physics
Authors: Haindl Silvia , Kidszun Martin , Kampert Erik 
Published: September 2016

AbstractSuperconducting thin films play a prominent role in applications of superconductivity and provide an essential source for studying physical phenomena. Here, we summarize the activities for iron pnictide thin films with a focus on the German Special Priority Programme from 2009 until today. The quick availability of such films after the discovery of superconductivity in the iron‐based superconductors enabled a number of experiments. After a general introduction and a brief historical overview we focus on film synthesis of iron pnictides by a two‐step method and by pulsed laser deposition, the assessment of their application potential, the upper critical fields in iron oxypnictides of F‐doped LaOFeAs and F‐doped SmLaOFeAs and on superconductivity in Fe/BaFeAs heterostructures.
A Quality Assessment Framework for Large Datasets of Container-Trips Information
Authors: Makridis Michail , Fidalgo-Merino Raúl , Cotelo-Lema José-Antonio , Tsois Aris , Checchi Enrico 
Published: September 2016

AbstractCustoms worldwide are facing the challenge of supervising huge volumes of containerized trade arriving to their country with resources allowing them to inspect only a minimal fraction of it. Risk assessment procedures can support them on the selection of the containers to inspect. The Container-Trip information (CTI) is an important element for that evaluation, but is usually not available with the needed quality. Therefore, the quality of the computed CTI records from any data sources that may use (e.g. Container Status Messages), needs to be assessed. This paper presents a quality assessment framework that combines quantitative and qualitative domain specific metrics to evaluate the quality of large datasets of CTI records and to provide a more complete feedback on which aspects need to be revised to improve the quality of the output data. The experimental results show the robustness of the framework in highlighting the weak points on the datasets and in identifying efficiently cases of potentially wrong CTI records.
A&nbsp;journal club for peer mentorship: helping to navigate the transition to independent practice
Authors: MacMillan Thomas E. , Rawal Shail , Cram Peter , Liu Jessica 
Published: September 2016

The transition from residency to independent practice presents unique challenges for physicians. New attending physicians often have unmet learning needs in non-clinical domains. An attending physician is an independent medical practitioner, sometimes referred to as a staff physician or consultant. Peer mentorship has been explored as an alternative to traditional mentorship to meet the learning needs of new attendings. In this article, the authors describe how a journal club for general internal medicine fellowship graduates helped ease the transition by facilitating peer mentorship. Journal club members were asked to bring two things to each meeting: a practice-changing journal article, and a ‘transition to practice’ discussion topic such as a diagnostic dilemma, billing question, or a teaching challenge. Discussions fell into three broad categories that the authors have termed: trading war stories, measuring up, and navigating uncharted waters. It is likely that physicians have a strong need for peer mentorship in the first few years after the transition from residency, and a journal club or similar discussion group may be one way to fulfil this.
Peer attachment and class emotional intelligence as predictors of adolescents' psychological well‐being: A multilevel approach
Authors: Balluerka Nekane , Gorostiaga Arantxa , Alonso‐Arbiol Itziar , Aritzeta Aitor 
Published: September 2016

ABSTRACTThe aim of the study was to analyze whether gender, age, peer attachment, and class‐level emotional intelligence could predict adolescents' psychological well‐being by applying a multilevel approach. The sample comprised 2182 secondary school students from the Basque Country (northern Spain) (from 118 classrooms, 51.6% girls), aged between 12 and 18 years. A two‐level model (with students nested into classes) was used to analyze the influence of three level‐one covariates (gender, age, and peer attachment) and one level‐two covariate (class‐level emotional intelligence) on the positive affect component of psychological well‐being. The results showed an overall decrease in well‐being as adolescents grow older, and an increase linked to a higher peer attachment. Furthermore, class‐level emotional intelligence showed a positive relationship with students' well‐being. This group‐level covariate also strengthened the effect of peer attachment on the well‐being. The advantages of using a multilevel approach for predicting mental health and psychological adjustment are discussed.
Brief report: Agreement between parent and adolescent autonomy expectations and its relationship to adolescent adjustment☆
Authors: Pérez J. Carola , Cumsille Patricio , Martínez M. Loreto 
Published: September 2016

ABSTRACTWhile disagreement in autonomy expectations between parents and their adolescent children is normative, it may also compromise adolescent adjustment. This study examines the association between parents' and adolescents' agreement on autonomy expectations by cognitive social domains and adolescent adjustment. A sample of 211 Chilean dyads of adolescents (57% female, Mage = 15.29 years) and one of their parents (82% mothers, Mage = 44.36 years) reported their expectations for the age at which adolescents should decide on their own regarding different issues in their life. Indexes of parent–adolescent agreement on autonomy expectations were estimated for issues of personal and prudential domains. Greater agreement in the prudential than in the personal domain was observed. For boys and girls, higher agreement in adolescent–parent autonomy expectations in the personal domain was associated with lower substance use. A negative association between level of agreement in adolescent–parent autonomy expectations in the prudential domain and externalizing behaviors and substance use was found.
Prognostic Importance of C-KIT Mutations in Core Binding Factor Acute Myeloid Leukemia
Authors: Ayatollahi Hossein , Shajiei Arezoo , Sadeghian Mohammad Hadi , Sheikhi Maryam , Yazdandoust Ehsan , Ghazanfarpour Masumeh , Shams Seyyede Fatemeh , Shakeri Sepideh 
Published: September 2016

Objective/background:
Acute myeloid leukemia (AML) is defined as leukemic blast reproduction in bone marrow. Chromosomal abnormalities form different subgroups with joint clinical specifications and results. t(8;21)(q22;q22) and inv(16)(p13;q22) form core binding factor- AML (CBF-AML). c-kit mutation activation occurs in 12.8–46.1% of adults with CBF leukemia. These mutations occur in 20–25% of t(8;21) and 30% of inv(16) cases.

Methods:
In this systematic review, we searched different databases, including PubMed, Scopus, and Embase. Selected articles were measured based on the inclusion criteria of this study and initially compared in terms of titles or abstracts. Finally, articles relevant to the subject of this review were retrieved in full text. Twenty-two articles matched the inclusion criteria and were selected for this review.

Results:
In this study, c-kit mutations were associated with poor prognosis in AML patients with t(8;21) and inv(16). In addition, these mutations had better prognostic effects on AML patients with inv(16) compared with those with t(8;21).

Conclusion:
According to the results of this study, c-kit mutations have intense, harmful effects on the relapse and white blood cell increase in CBF-AML adults. However, these mutations have no significant prognostic effects on patients.
The influence of cavity's diamond pattern on the performance of gas dynamic lasers
Authors: Tahsini A.M. 
Published: September 2016

ABSTRACTThe gas dynamic laser is numerically studied using quasi-1D and 2D simulations to investigate the effect of diamond pattern of the supersonic flow field (inhomogeneities in density field) on the laser's performance. The system of governing equations is solved with a finite volume approach using a structured grid in which the AUSM+ scheme is used to calculate the convective fluxes. Vibrational temperature of different modes, population inversion and the small signal gain are studied, and the effect of the divergent nozzle's geometry at the maximum gain is analysed.
Hemorrhagic shock primes for lung vascular endothelial cell pyroptosis: role in pulmonary inflammation following LPS
Authors: Yang Jie , Zhao Yanfeng , Zhang Peng , Li Yuehua , Yang Yong , Yang Yang , Zhu Junjie , Song Xiao , Jiang Gening , Fan Jie 
Published: September 2016

AbstractHemorrhagic shock (HS) often renders patients more susceptible to lung injury by priming for an exaggerated response to a second infectious stimulus. Acute lung injury (ALI) is a major component of multiple organ dysfunction syndrome following HS and regularly serves as a major cause of patient mortality. The lung vascular endothelium is an active organ that has a central role in the development of ALI through synthesizing and releasing of a number of inflammatory mediators. Cell pyroptosis is a caspase-1-dependent regulated cell death, which features rapid plasma membrane rupture and release of proinflammatory intracellular contents. In this study, we demonstrated an important role of HS in priming for LPS-induced lung endothelial cell (EC) pyroptosis. We showed that LPS through TLR4 activates Nlrp3 (NACHT, LRR, and PYD domains containing protein 3) inflammasome in mouse lung vascular EC, and subsequently induces caspase-1 activation. However, HS induced release of high-mobility group box 1 (HMGB1), which acting through the receptor for advanced glycation end products initiates EC endocytosis of HMGB1, and subsequently triggers a cascade of molecular events, including cathepsin B release from ruptured lysosomes followed by pyroptosome formation and caspase-1 activation. These HS-induced events enhance LPS-induced EC pyroptosis. We further showed that lung vascular EC pyroptosis significantly exaggerates lung inflammation and injury. The present study explores a novel mechanism underlying HS-primed ALI and thus presents a potential therapeutic target for post-HS ALI.
Time distortions in Alzheimer’s disease: a systematic review and theoretical integration
Authors: El Haj Mohamad , Kapogiannis Dimitrios 
Published: September 2016

AbstractTime perception is an essential function of the human brain, which is compromised in Alzheimer’s disease (AD). Here, we review empirical findings on time distortions in AD and provide a theoretical framework that integrates time and memory distortions in AD and explains their bidirectional modulation. The review was based on a literature survey performed on the PubMed and PsycInfo databases. According to our theoretical framework, time distortions may induce decline in the ability to mentally project oneself in time (i.e., mental time travel), and consequently may contribute to an episodic memory compromise in AD. Conversely, episodic memory compromise in AD may result in a loss of the ability to retrieve information about time and/or the ability to project oneself in subjective time. The relationship between time distortions and memory decline in AD can be jointly attributed to hippocampus involvement, as this brain area supports both time perception and memory and is preferentially targeted by the neuropathological processes of AD. Clinical implications of time distortions are discussed and directions for future research are suggested.
Visualising phase change in a brushite-based calcium phosphate ceramic
Authors: Bannerman A. , Williams R. L. , Cox S. C. , Grover L. M. 
Published: September 2016

AbstractThe resorption of brushite-based bone cements has been shown to be highly unpredictable, with strong dependence on a number of conditions. One of the major factors is phase transformation, with change to more stable phases such as hydroxyapatite affecting the rate of resorption. Despite its importance, the analysis of phase transformation has been largely undertaken using methods that only detect crystalline composition and give no information on the spatial distribution of the phases. In this study confocal Raman microscopy was used to map cross-sections of brushite cylinders aged in Phosphate Buffered Saline, Foetal Bovine Serum, Dulbecco’s – Minimum Essential Medium (with and without serum). Image maps showed the importance of ageing medium on the phase composition throughout the ceramic structure. When aged without serum, there was dissolution of the brushite phase concomitant to the deposition of octacalcium phosphate (OCP) around the periphery of the sample. The deposition of OCP was detectable within five days and reduced the rate of brushite dissolution from the material. The use of serum, even at a concentration of 10vol% prevented phase transformation. This paper demonstrates the value of confocal Raman microscopy in monitoring phase change in biocements; it also demonstrates the problems with assessing material degradation in non-serum containing media.