bluuebunny/crossref_metadata_2025_split huggingface dataset:
Myositis following spine radiosurgery for metastatic disease: a case series
Authors: Lockney Dennis T. , Jia Angela Y. , Lis Eric , Lockney Natalie A. , Liu Chengbao , Hopkins Benjamin , Higginson Daniel S. , Yamada Yoshiya , Laufer Ilya , Bilsky Mark , Schmitt Adam M. 
Published: January 2018

OBJECTIVESpinal stereotactic body radiation therapy (SBRT) has emerged as an attractive method to deliver high doses of radiation to oligometastatic spinal tumors with radioresistant histology. Because SBRT is a palliative therapy, attention to potential radiation toxicities is paramount when counseling patients. The objective of this study was to report radiation-induced myositis after SBRT, a previously undescribed complication.METHODSA total of 667 patients received 891 spine SBRT treatments (either 24 Gy in 1 fraction or 27 Gy in 3 fractions) from 2011 to 2016 and underwent retrospective review. Eleven patients were identified as having radiographic evidence of myositis following SBRT. Clinical and pathologic results were collected, including receipt of anti–vascular endothelial growth factor (VEGF) therapy, radiation dose, equivalent dose in 2-Gy fractions (EQD2), biologically effective dose (BED), and volume of muscle treated. Treatment toxicities were classified according to the Common Terminology Criteria for Adverse Events (CTCAE; version 4.03). Univariate statistical analyses were performed to evaluate the relationships between radiation fractionation schedule and myositis and between anti-VEGF therapy and myositis.RESULTSThe cumulative incidence of myositis was 1.9% at 1 year. The median of the mean dose administered to muscle with myositis was 17.5 Gy. The median EQD2 was 55.1 Gy, and the median BED was 82.7 Gy. The median time to the development of clinical symptoms was 1.4 months, while the median time to imaging evidence was 4.7 months. Two patients (18.2%) had CTCAE grade 3 complications. Single-fraction spine SBRT (HR 4.5, 95% CI 1.2–16.9; p = 0.027) was associated with increased risk of developing myositis whereas receipt of anti-VEGF therapy was not (HR 2.2, 95% CI 0.6–7.1; p = 0.2).CONCLUSIONSRadiation myositis following spinal radiosurgery is a rare but important complication. Single-fraction treatment schedules may be associated with increased risk of myositis but should be validated in a larger series.
Safety and efficacy of balloon kyphoplasty at 4 or more levels in a single anesthetic session
Authors: Wang Alan C. , Fahim Daniel K. 
Published: January 2018

OBJECTIVEIn this case series, the authors evaluated the safety of balloon kyphoplasty at 4 or more vertebral levels in a single anesthetic session. The current standard is that no more than 3 levels should be cemented at one time because of a perceived risk of increased complications.METHODSA retrospective chart review was performed for 19 consecutive patients who underwent ≥ 4-level balloon kyphoplasty between July 1, 2011, and December 31, 2015. Outcomes documented included kyphoplasty-associated complications and incidences of subsequent vertebral fracture.RESULTSNineteen patients aged 22 to 95 years (mean 66.1 years, median 66 years; 53% male, 47% female) had 4 or more vertebrae cemented during the same procedure (mean 4.6 levels [62 thoracic, 29 lumbar]). No postoperative anesthetic complication, infection, extensive blood loss, symptomatic cement leakage, pneumothorax, or new-onset anemia was observed. Five patients experienced new compression fracture within a mean of 278 days postoperatively. One patient with metastatic cancer suffered bilateral pulmonary embolism 19 days after surgery, but no evidence of cement in the pulmonary vasculature was found.CONCLUSIONSIn this case series, kyphoplasty performed on 4 or more vertebral levels was not found to increase risk to patient safety, and it might decrease unnecessary risks associated with multiple operations. Also, morbidity associated with leaving some fractures untreated because of an unfounded fear of increased risk of complications might be decreased by treating 4 or more levels in the same anesthetic session.
Anatomy of the Chase
Authors: Grahne Gösta , Onet Adrian 
Published: January 2018

A lot of research activity has recently taken place around the chase procedure, due to its usefulness in data integration, data exchange, query optimization, peer data exchange and data correspondence, to mention a few. As the chase has been investigated and further developed by a number of research groups and authors, many variants of the chase have emerged and associated results obtained. Due to the heterogeneous nature of the area it is frequently difficult to verify the scope of each result. In this paper we take closer look at recent developments, and provide additional results. Our analysis allows us create a taxonomy of the chase variations and the properties they satisfy. Two of the most central problems regarding the chase is termination, and discovery of restricted classes of sets of dependencies that guarantee termination of the chase. The search for the restricted classes has been motivated by a fairly recent result that shows that it is undecidable (RE-complete, to be more precise) to determine whether the chase with a given dependency set will terminate on a given instance. There is a small dissonance here, since the quest has been for classes of sets of dependencies guaranteeing termination of the chase on all instances, even though the latter problem was not known to be undecidable. We resolve the dissonance in this paper by showing that determining whether the chase with a given set of dependencies terminates on all instances is unsolvable, and on level ∏20 in the Arithmetical Hierarchy. For this we use a reduction from word rewriting systems, thereby also showing the close connection between the chase and word rewriting. The same reduction also gives us the aforementioned instance-dependent RE-completeness result as a byproduct. For one of the restricted classes guaranteeing termination on all instances, the stratified sets dependencies, we provide new complexity results for the problem of testing whether a given set of dependencies belongs to it. These results rectify some previous claims that have occurred in the literature.
The influence of upper limb immobilization on lower limb muscular activity during the sit-to-stand task
Authors: Leal Viviana , Ventura Liliana , Alexandre Lopes A. , Mesquita Inês , Torres Rui , Castro Marcelo 
Published: January 2018

PURPOSE: The aim of this study was to compare the magnitude and pattern of lower limb muscular activity during the sit-to-stand (STS) task with and without upper limb immobilization. METHODS: The activity of six muscles from each lower limb (Rectus Femoris, Vastus Medialis, Biceps Femoris, Tibialis Anterior, Gastrocnemius Medialis and Soleus) were recorded while 19 young healthy participants performed the STS task with and without an arm sling on their dominant side. Myoelectric signals were collected using BioPlux Research device, and two Bertec force platforms were used to determine different phases of the STS task. The peak of muscular activity and muscle onset times were calculated, two general linear models with an alpha of 0.05 were used between the conditions with and without upper limb immobilization. RESULTS: We found no statistically significant differences in the onset of lower limb muscular activity, and we observed decreased peak of muscular activity in the Rectus Femoris at the immobilized side and an increased peak in the Vastus Medialis at the side opposite to the upper limb immobilized compared to the control condition. CONCLUSIONS: We did observe differences in the magnitude of ipsilateral Rectus Femoris and contralateral Vastus Medialis as a consequence of upper limb immobilization.
Mobility outcomes for those with primary lower limb amputation attending a regional outpatient prosthetic rehabilitation service
Authors: Collins Aoife , Timmons Suzanne 
Published: January 2018

BACKGROUND: There is an age-related increase in lower limb amputation (LLA) secondary to dysvascular disease, however, the effectiveness of Multi-Disciplinary Team (MDT) is unknown. PURPOSE: The aims of the study were to investigate if a) individuals with primary lower limb amputation (IPLLAs) attending a regional outpatient prosthetic rehabilitation service achieve successful mobility outcomes, b) to examine the multi-disciplinary team’s ability to accurately predict mobility outcome in this cohort and c) to evaluate how pre-amputation mobility levels affect mobility outcomes of IPPLAs attending an outpatient rehabilitation service. METHODS: This retrospective observational cohort study included 93 primary, unilateral and bilateral IPPLAs at or proximal to the transtibial level. Pre-rehabilitation (baseline) data was collected between one and six weeks after amputation when clients attended for their pre-rehabilitation MDT Assessment. This data (including Specialist Interest in Amputee Medicine (SIGAM) Score and Pre-Amputation Mobility Status) was gathered to establish their rehabilitation needs. Pre-amputation mobility was characterised as 1) Ambulatory (independent ambulation out of house); 2) Ambulatory/homebound (ambulatory in the home only), 3) Nonambulatory/transfer, 4) Nonambulatory/bedridden. Peri- and post-rehabilitation data (Timed Walking Test (TWT), Locomotor Capabilities Index 5 (LCI-5) and SIGAM Score) was collected at six weeks, six months and twelve months after delivery of prosthesis to the client. RESULTS: Fifty-six percent of participants who completed the 12 month post rehabilitation assessment ( n = 68) achieved mobility success. (success was defined as returning to or exceeding baseline mobility scores on the SIGAM for those scoring C-F, and for those who scored A or B at baseline, moving up one category (i.e. going from A to B, or B to C). The pre-rehabilitation SIGAM score was used as a predictor of the IPLLAs expected mobility outcome. There was a highly significant correlation between pre-rehabilitation and 12 month post-rehabilitation SIGAM scores, ( r = 0.89, n = 68, p < 0.001) demonstrating that the MDT’s predictions significantly correlated to the post-rehabilitation SIGAM scores. There was a highly significant association between pre-amputation mobility levels and mobility success post-rehabilitation at 12 month follow-up ( χ2 (3) = 26.43, p < 0.001), such that those who were ambulatory independently pre-amputation were significantly more likely to achieve mobility success post-rehabilitation. CONCLUSION: IPLLAs attending an outpatient rehabilitation service can achieve successful mobility outcomes. The MDT was found to be accurate in its predictions of mobility outcome in this cohort. Greater pre-amputation mobility was significantly associated with successful mobility outcomes.
Promoting physical activity for health. A survey of knowledge, confidence and role-perception in final-year UK physiotherapy students
Authors: Clifford Ross 
Published: January 2018

BACKGROUND: Physical inactivity is the fourth leading cause of global mortality and is a significant independent risk factor for a range of chronic conditions. Advice from a healthcare professional can increase activity levels in adults. Current literature does not identify whether UK physiotherapy undergraduate students are prepared to promote physical activity (PA) for health. PURPOSE: The aim of this study was to determine the knowledge, confidence and role perception of final-year UK Physiotherapy undergraduate students to promote physical activity for health. METHODS: An online cross-sectional survey was used. 19 UK undergraduate Physiotherapy courses participated. Descriptive statistics explored knowledge, confidence and role-perception. Inferential statistics tested the relationships between variables. RESULTS: Response rate was 16.6% ( n = 158). The majority of respondents (82% n = 129) had received training in promoting PA for health. 66% ( n = 73) of this group correctly specified a duration, frequency and intensity for current UK PA recommendations for 19–64 year olds. Role perception was extremely high (99%) in the surveyed population. Students reported being confident in giving general PA advice (92%, n = 144). Confidence scores were significantly correlated with training in the promotion of PA for health ( β= 0.38 p < 0.001). CONCLUSION: Final-year UK Physiotherapy students perceive a professional role in promoting physical activity for health; and demonstrate good but variable knowledge of this subject. Confidence domain scores were best predicted by training in the promotion of PA for health.
Evaluation of biofeedback based bridging exercises on older adults with low back pain: A randomized controlled trial
Authors: Feldwieser Florian , Kiselev Joern , Hardy Sandro , Garcia-Agundez Augusto , Eicher Cornelia , Steinhagen-Thiessen Elisabeth , Göbel Stefan 
Published: January 2018

BACKGROUND: Low back pain (LBP) is a common cause for disabilities and reduced autonomy in older adults. Exercise therapy has shown to be effective in the reduction of the symptoms of LBP with bridging exercises as a commonly used intervention. Exercise therapy can be supported with biofeedback-based methods in order to further improve motor control. The availability of relatively inexpensive devices like the Nintendo Wii opens up new methods for the treatment for biofeedback-based exercises for patients with LBP. METHODS: We conducted a 3-armed randomized controlled trial (biofeedback, standard care and control) with 62 older adults aged 66 to 89 years and an intervention period of twelve weeks with 2 sessions/week. Primary outcome was the perceived disability using the Oswestry Disability Index (ODI). Additionally, we evaluated usability and user acceptance of the feedback system. RESULTS: The biofeedback group demonstrated significantly lower levels of perceived disability compared to the control group. Additionally, the Biering-Sørensen test was significantly better in the standard care group compared to both other groups. Usability and user-acceptance for the biofeedback system was low, mostly because of connectivity and comfort problems during exercising. CONCLUSIONS: The biofeedback system was able to significantly improve perceived disability and back extensor muscle endurance in older people with subacute low back pain. As the user-acceptance issues were mostly based on technical reasons, higher levels of comfort and dependability of the system could provide an effective method to perform bridging exercises to alleviate the consequences of episodes of low back pain.
Economic Impact of Practicing IPM Technology on Bitter Gourd (<i>Momordica charantia</i> L.) Production in Comilla District of Bangladesh
Authors: Islam S , Islam D M S , Khanum R 
Published: January 2018

The present study was conducted to assess the economic impact of practicing Integrated Pest Management technology on bitter gourd production in Chandina upazila under Comilla district of Bangladesh. Sample survey was carried out over 70 bitter gourd producing farms. Out of 70 farmers, 35 for IPM and 35 for Non-IPM farmers were selected. The study revealed that majority of the farmers had moderately favorable attitude towards IPM technology for producing bitter gourd as shown by farmers’ attitude index. IPM farmers earned more profit than Non-IPM farmers on bitter gourd production. The average total cost of bitter gourd production per hectare was estimated at about Tk 3,68,335 and 4,44,508 for IPM and Non-IPM farmers, respectively. The average gross returns per hectare were found at about Tk 8,60,016; 8,55,642; and 8,15,947 for marginal, small and medium IPM farmers, respectively. The same were Tk 8,22,654; 7,53,373 and 7,48,255 for marginal, small, and medium Non-IPM farmers, respectively. The estimated BCR was higher for IPM farmers (2.29) than Non-IPM farmers (1.69). Partial budget analysis showed that IPM technology was more profitable and net benefit was Tk 1,61,557. Although bitter gourd production was profitable, farmers faced several problems such as lack of training and technical knowledge, inadequate extension services, lack of marketing facilities etc. in using IPM technology.The Agriculturists 2017; 15(2) 11-23
Le massif du Seuil (Chartreuse, France) : organisation des réseaux souterrains
Authors: Loiseleur Bernard 
Published: January 2018

"W e massif du Seuil (~ 13 km2) M se trouve sur le synclinal
oriental de Chartreuse. Au nord et au sud de ce synclinal, on trouve plusieurs des plus importants réseaux souterrains français. Les deux principales cavités du Seuil, non reliées entre elles, sont la grotte du Mort Rû 7 km) et le réseau du Guiers Vif (~ 15 km de développement), connecté avec le Trou des Flammes. Dans ces dernières années, la connaissance de ces systèmes a beaucoup progressé et plusieurs jonctions avec le plateau ont été réalisées (Masques -Mort Rû, Tasurinchi -Guiers Vif, Trou des Flammes -Guiers Vif). Mais la rivière de Malissard, la branche principale du réseau du Guiers Vif est située sous les Lances de Malissard, sur la bordure ouest du massif. Une telle situation s'explique par la disposition excentrée de l'axe synclinal. L'espoir est de découvrir un réseau comparable à ceux de la Dent de Crolles et de l'Alpe. Le collecteur principal semble devoir se situer dans l'axe du massif, sur la faille du GR9. Dans les années à venir, la comparaison de l'évolution des divers systèmes de Chartreuse montre que cet espoir est raisonnable.
Le Chili, pays de karsts extrêmes
Authors: Salomon Jean-Noël 
Published: January 2018

Bien que très étendu, le Chili n'apparaît pratiquement pas dans les chroniques spéléologiques et karstologiques.
Cela tient à la nature géologique essentiellement métamorphique et volcanique du pays. Pourtant on y rencontre des phénomènes karstiques dans des affleurements de gypse et de halite et dans des calcaires. Ceci est d'autant plus intéressant sur le plan scientifique que le Chili s'étire en latitude depuis le climat aride du désert d'Atacama au nord (1 mm/an à Iquique) aux îles hyper-humides de Patagonie (> 4 000 mm/an).
Searching for Be Stars in the Open Clusters with PTF/iPTF. I. Cluster Sample and Be Star Candidates
Authors: Yu 俞伯 Po-Chieh 傑 , Yu 游昌 Chang-Hsien 憲 , Lee 李建 Chien-De 德 , Lin 林建 Chien-Cheng 爭 , Hsia 夏志 Chih-Hao 浩 , Chang 章展 Chang-Kao 誥 , Chen 陳以 I-Chenn 忱 , Ngeow 饒兆 Chow-Choong 聰 , Ip 葉永 Wing-Huen 烜 , Chen 陳文 Wen-Ping 屏 , Laher 良主嶺 Russ 亞 , Surace Jason , Kulkarni Shrinivas R. 
Published: January 2018

Abstract
We conducted a search for Be star candidates in open clusters using Hα imaging photometry of the Palomar Transient Factory Survey to investigate some connections among Be star phenomena, cluster environments, and ages. Stellar members of clusters were identified by spatial distributions, near-infrared magnitudes and colors, and by proper motions. Among 104 open clusters, we identified 96 Be star candidates in 32 clusters; 11 of our candidates have been reported in previous studies. We found that the clusters with age 7.5 < log(t(year))

8.5 tend to have more Be star candidates; there is about a 40% occurrence rate within this age bin. The clusters in this age bin also tend to have a higher Be fraction N(Be)/N(Be+B-type). These results suggest that the environments of young and intermediate clusters are favorable to the formation of Be phenomena. Spatial distribution of Be star candidates with different ages implies that they do not form preferentially in the central regions. Furthermore, we showed that the mid-infrared (MIR) colors of the Be star candidates are similar to known Be stars, which could be caused by free–free emission or bound-free emission. Some Be star candidates might have no circumstellar dust according to their MIR colors. Finally, among 96 Be candidates, we discovered that one Be star candidate FSR 0904-1 exhibits long-term variability on the timescale of ∼2000 days with an amplitude of 0.2–0.3 mag, indicating a long timescale of disk evolution.
On the Factors Determining the Eruptive Character of Solar Flares
Authors: Baumgartner Christian , Thalmann Julia K. , Veronig Astrid M. 
Published: January 2018

Abstract
We investigated how the magnetic field in solar active regions (ARs) controls flare activity, i.e., whether a confined or eruptive flare occurs. We analyzed 44 flares of GOES class M5.0 and larger that occurred during 2011–2015. We used 3D potential magnetic field models to study their location (using the flare distance from the flux-weighted AR center d
FC) and the strength of the magnetic field in the corona above (via decay index n and flux ratio). We also present a first systematic study of the orientation of the coronal magnetic field, using the orientation φ of the flare-relevant polarity inversion line as a measure. We analyzed all quantities with respect to the size of the underlying dipole field, characterized by the distance between the opposite-polarity centers, d
PC. Flares originating from underneath the AR dipole (d
FC/d
PC < 0.5) tend to be eruptive if launched from compact ARs (d
PC ≤ 60 Mm) and confined if launched from extended ARs. Flares ejected from the periphery of ARs (d
FC/d
PC > 0.5) are predominantly eruptive. In confined events, the flare-relevant field adjusts its orientation quickly to that of the underlying dipole with height (Δφ ≳ 40° until the apex of the dipole field), in contrast to eruptive events where it changes more slowly with height. The critical height for torus instability, h
crit = h(n = 1.5), discriminates best between confined (h
crit ≳ 40 Mm) and eruptive flares (h
crit ≲ 40 Mm). It discriminates better than Δφ, implying that the decay of the confining field plays a stronger role than its orientation at different heights.
Oscillation Mode Variability in Evolved Compact Pulsators from Kepler Photometry. I. The Hot B Subdwarf Star KIC 3527751
Authors: Zong Weikai , Charpinet Stéphane , Fu Jian-Ning , Vauclair Gérard , Niu Jia-Shu , Su Jie 
Published: January 2018

Abstract
We present the first results of an ensemble and systematic survey of oscillation mode variability in pulsating hot B subdwarf (sdB) and white dwarf stars observed with the original Kepler mission. The satellite provides uninterrupted high-quality photometric data with a time baseline that can reach up to 4 yr collected on pulsating stars. This is a unique opportunity to characterize long-term behaviors of oscillation modes. A mode modulation in amplitude and frequency can be independently inferred by its fine structure in the Fourier spectrum, from the sLSP, or with prewhitening methods applied to various parts of the light curve. We apply all these techniques to the sdB star KIC 3527751, a long-period-dominated hybrid pulsator. We find that all the detected modes with sufficiently large amplitudes to be thoroughly studied show amplitude and/or frequency variations. Components of three identified quintuplets around 92, 114, and 253 μHz show signatures that can be linked to nonlinear interactions according to the resonant mode coupling theory. This interpretation is further supported by the fact that many oscillation modes are found to have amplitudes and frequencies showing correlated or anticorrelated variations, a behavior that can be linked to the amplitude equation formalism, where nonlinear frequency corrections are determined by their amplitude variations. Our results suggest that oscillation modes varying with diverse patterns are a very common phenomenon in pulsating sdB stars. Close structures around main frequencies therefore need to be carefully interpreted in light of this finding to secure a robust identification of real eigenfrequencies, which is crucial for seismic modeling. The various modulation patterns uncovered should encourage further developments in the field of nonlinear stellar oscillation theory. It also raises a warning to any long-term project aiming at measuring the rate of period change of pulsations caused by stellar evolution, or at discovering stellar (planetary) companions around pulsating stars using timing methods, as both require very stable pulsation modes.