bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing Pain Anxiety in Adolescents
Authors: Sánchez-Rodríguez Elisabet , Tomé-Pires Catarina , Castarlenas Elena , de la Vega Rocío , Galán Santiago , Jensen Mark P. , Miró Jordi 
Published: February 2016

Objectives:
Emotional responses to pain are known to play an important role in the development and maintenance of pain. To better understand the role that pain anxiety plays in chronic pain, as well as to evaluate treatments that might treat it effectively, reliable and valid measures of pain anxiety are needed. Thus, the aim of this study was to provide additional evidence regarding the psychometric properties of the Child Pain Anxiety Symptoms Scale (CPASS) in a sample of adolescents.

Methods:
A total of 357 adolescents ages 12 to 19 years completed measures of pain anxiety (CPASS), pain-related catastrophizing (PCS-C), anxiety sensitivity (CASI), and sleep quality (NRS-Sleep). We used confirmatory factor analyses to evaluate the factor structure of CPASS items. We also tested the reliability and the validity of CPASS scores.

Results:
Confirmatory factor analyses suggested a 4-factor structure with a single higher-order factor (CFI=0.91, TLI=0.95, RMSEA=0.078). The total score of CPASS showed good internal consistency (α=0.87) and adequate validity as evidenced by (1) moderate to high correlations between CPASS-PCS-C (r=0.74, P<0.001) and CPASS-CASI (r=0.48, P<0.001) and (2) the magnitude of the correlations between CPASS-PCS-C and CPASS-CASI being significantly greater than that between CPASS and NRS-Sleep (z=14.70 and 8.96, respectively; P<0.001).

Discussion:
The findings support the reliability and the validity of CPASS as a measure of pain-related anxiety in adolescents.
Three-dimensional Cervical Movement Characteristics in Healthy Subjects and Subgroups of Chronic Neck Pain Patients Based on Their Pain Location
Authors: Waeyaert Patirck , Jansen Daniel , Bastiaansen Marco , Scafoglieri Aldo , Buyl Ronald , Schmitt Maarten , Cattrysse Erik 
Published: February 2016

Study Design.
A cross-sectional observational study of three-dimensional (3D) cervical kinematics in 41 chronic neck pain (CNPs) patients and 156 asymptomatic controls.

Objective.
The objective was to investigate 3D cervical kinematics by analyzing and comparing quantitative and qualitative parameters in healthy subjects and CNPs. Furthermore, subgroups were formed to explore the influence of pain-location on cervical kinematics. The possible correlation of kinematic parameters with the degree of functional disability was examined as well.

Summary of Background Data.
In patients with chronic neck pain, a clear pathological cause is frequently not identifiable. Therefore, the need to assess neck pain with a broader view than structure or anatomical-based divergences is desirable.

Methods.
Movements of the cervical spine were registered using an electromagnetic tracking system. Quantitative and qualitative kinematics were analyzed for active axial rotation, lateral bending, and flexion-extension motion components.

Results.
During lateral bending, the range of the main motion demonstrated significant higher values (P = 0.001) in the controls (mean: 68.67° ± 15.17°) than patients (mean: 59.28° ± 15.41°). Significant differences were demonstrated between subgroups for several kinematic parameters (P < 0.05). Although differences were predominantly recorded between the “symmetrical” and “asymmetrical” pain group, some parameters also distinguished subgroups from controls. On average, the symmetrical group showed significant less harmonic movement patterns, expressed by qualitative parameters, in comparison with the “asymmetrical” group and controls. Furthermore, the “asymmetrical” group showed significant lower scores on quantitative parameters than the “symmetrical” group and controls. The degree of functional disability correlated moderately with changes in qualitative parameters.

Conclusion.
In this study, chronic neck pain patients with a symmetrical pain pattern showed significant poorer quality of movement, while those with asymmetrical pain showed a significant reduction in quantitative measures. Subgrouping of neck patients based on pain location may be of help for further research and clinics.

Level of evidence: 4
European experience with methotrexate treatment in Crohn’s disease: a multicenter retrospective analysis
Authors: Kopylov Uri , Katsanos Konstantinos H. , van der Woude Christien Janneke , Karmiris Konstantinos , Hernandez Vicent , Odes Selwyn , Papamichael Konstantinos , Koutroubakis Ioannis E. , Bojic Daniela , Kaimakliotis Ioannis , Fiorino Gionata , Papageorgiou Neofytos , Pineda Juan R. , Strongili Konstantina , Sanroman Luciano , Mantzaris Gerassimos J. , Jojic Njegica , Paspatis Gregorios , Christodoulou Dimitrios K. , Ben-Horin Shomron , Tsianos Epameinondas V. 
Published: February 2016

Introduction
Methotrexate (MTX) has been utilized for the treatment of Crohn’s disease (CD) for decades. Nevertheless, current data provide equivocal evidence on the efficacy of MTX in CD.
The aims of this study were to describe the efficacy of MTX for maintenance of remission in CD and to identify the factors associated with the probability of steroid-free clinical remission in a multicenter European referral center cohort.

Patients and methods
This was a retrospective cohort analysis. Consecutive patients treated with MTX for CD were included from 11 referral centers. Patients receiving concomitant treatment with tumor necrosis factor inhibitors or thiopurines were excluded. The main outcome was steroid-free clinical remission; the secondary outcomes included the rate of complications leading to MTX discontinuation and duration of relapse-free survival in patients achieving the main outcome.

Results
Between July 1992 and January 2012, 118 patients were identified for inclusion. MTX administration route was oral for induction in 31.4% and for maintenance in 49.1% of the patients. Steroid-free remission was achieved in 44/118 (37.2%) patients and was maintained relapse free by 28/44 (63.6%) for a median of 12 (3.5–18.5) months. At least one adverse effect was reported by 28.9% of the patients. No clinical or demographic factors were associated with either likelihood of achieving a clinical response or duration of relapse-free survival.

Conclusion
MTX treatment induced steroid-free clinical remission in over a third of CD patients and maintained it for a year in almost two-thirds of the responders. MTX should be considered a viable therapeutic option in CD patients refractory to other therapies.
Improved detection of delirium, implementation and validation of the CAM-ICU in elderly Emergency Department patients
Authors: Van de Meeberg Evelien K. , Festen Suzanne , Kwant Marieke , Georg Rita R. , Izaks Gerbrand J. , ter Maaten Jan C. 
Published: February 2016

Objective
To evaluate the effect of routine use of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) on the diagnosis rate of delirium in elderly Emergency Department (ED) patients and the validity of the CAM-ICU in the ED setting.

Methods
This was a prospective observational study in a tertiary care academic ED. We compared the diagnosis rate of delirium before implementation of the CAM-ICU, without routine use of a screening tool, with the diagnosis rate after implementation of the CAM-ICU. All consecutive patients aged 70 years or older were enrolled. The diagnosis rate before implementation was based on chart review and after implementation on a positive CAM-ICU score. In a subsample, the presence of delirium was evaluated independently according to the Diagnostic and Statistical Manual of Mental Disorders, 4th ed., text revision (DSM-IV-TR) criteria to assess the validity of the CAM-ICU.

Results
The total study population included 968 patients: 490 before and 478 after implementation of the CAM-ICU. The two groups were not significantly different in patient characteristics. Before implementation of the CAM-ICU, delirium was diagnosed in 14 patients (3%) and after implementation in 48 patients (10%) (P<0.001). The sensitivity of the CAM-ICU for delirium in the ED setting was 100%, specificity was 98%, positive predictive value was 92%, and negative predictive value was 100%.

Conclusion
The diagnosis rate of delirium after implementation of the CAM-ICU was three-fold higher than before. The CAM-ICU is a reliable screening tool in the ED, with high sensitivity, specificity, and positive and negative predictive value.
An Abundance of Selves
Authors: Hammond Chad , Teucher Ulrich 
Published: February 2016

Background:
Identity negotiations of people living with cancer have been shown to be significant psychosocial challenges throughout cancer trajectories but have not been adequately explored among young adults with cancer. Narrative approaches might help to reveal moments of (dis)empowerment that affect their identity negotiations.

Objective:
The aim of this study is to explore how young adults speak to their identities in relation to their narratives of having cancer and receiving care.

Methods:
A total of 21 young adults (18–45 years old) provided cancer narratives through semistructured life history interviews. Thematic narrative analysis was used to determine how participants represented themselves in their stories.

Results:
Participants used a wide diversity of identities well beyond those most familiar in dominant discourses (eg, patients, survivors, and fighters), and their identities frequently changed at significant “turning points” in their narratives, especially in relation to good and bad experiences of care.

Conclusions:
Cancer-related identities often undergo personal and social negotiation over time, and not just among young adults still feeling the effects of treatment. Psychosocial oncology could take further steps toward incorporating this fluidity and multiplicity within the discipline’s discourses of identity.

Implications for Practice:
The identities gathered here may contribute to a more comprehensive toolkit of narrative resources for empowering young adults (and others) with cancer, serving as a starting point for negotiating identities with their care providers. Our findings raise questions about which identities should be fostered and how healthcare professionals might be (unknowingly) involved in patients’ identity negotiations.
The Association Between Childhood Seizures and Later Childhood Emotional and Behavioral Problems: Findings From a Nationally Representative Birth Cohort
Authors: Kariuki Symon M. , Newton Charles R.J.C. , Prince Martin J. , Das-Munshi Jayati 
Published: February 2016

ABSTRACT

Objectives
Emotional/behavioral disorders are often comorbid with childhood epilepsy, but both may be predicted by social disadvantage and fetal risk indicators (FRIs). We used data from a British birth cohort, to assess the association of epilepsy, single unprovoked seizures, and febrile seizures with the later development of emotional/behavioral problems.

Methods
A total of 17,416 children in the 1958 British birth cohort were followed up until age 16 years. Logistic and modified Poisson regression models were used to determine a) the association of social disadvantage at birth and FRI with epilepsy, single unprovoked seizures, and febrile seizures at 7 years, and emotional/behavioral disorders in later childhood, and (ii) the association of childhood seizures by age 7 years with emotional/behavioral disorders in later childhood, after accounting for social disadvantage and FRI.

Results
Higher scores on FRI and social disadvantage were associated with emotional/behavioral problems at 7, 11, and 16 years, but not with seizure disorders at age 7 years. Epilepsy was associated with emotional/behavioral problems at 7 years (odds ratio [OR] = 2.50, 95% confidence interval [CI] = 1.29–4.84), 11 years (OR = 2.00, 95% CI = 1.04–3.81), and 16 years (OR = 5.47, 95% CI = 1.65–18.08), whereas single unprovoked seizures were associated with emotional/behavioral problems at 16 years (OR = 1.44, 95% CI = 1.02–2.01), after adjustment for FRI and social disadvantage. Febrile convulsions were not associated with increased risk for emotional/behavioral problems.

Conclusions
Emotional/behavioral problems in children are related to an earlier diagnosis of epilepsy and single unprovoked seizures after accounting for social disadvantage and FRI, whereas febrile convulsions are not associated with emotional/behavioral problems.
Osteosarcoma with apparent Ewing sarcoma gene rearrangement
Authors: Mathias Melissa , Chou Alexander J , Meyers Paul , Shukla Neerav , Hameed Meera , Agaram Narasimhan , Wang Lulu , Berger Michael F. , Walsh Michael , Kentsis Alex 
Published: February 2016

ABSTRACTPoorly differentiated round cell sarcomas present diagnostic challenges due to their variable morphology and lack of specific immunophenotypic markers. We present a case of a 15-year-old female with a tibial tumor that exhibited features of Ewing-like sarcoma, including apparent rearrangement of theEWSR1gene. Hybridization capture-based next-generation DNA sequencing showed evidence of complex genomic rearrangements, absence of known pathogenic Ewing-like chromosome translocations, and deletionsRB1, PTCH1, andATRX, supporting the diagnosis of osteosarcoma. This illustrates the potential of clinical genomic profiling to improve diagnosis and enable specifically targeted therapies for cancers with complex pathologies.
“I don’t know what fun is”: examining the intersection of social capital, social networks, and social recovery
Authors: Boeri Miriam , Gardner Megan , Gerken Erin , Ross Melissa , Wheeler Jack 
Published: February 2016

Purpose– The purpose of this paper is to understand how people with problematic drug use access positive social capital. Social capital is defined as relations that provide valuable resources to individuals through participation in social networks. People with low-socioeconomic status remain at a disadvantage for acquiring positive social capital, a component of recovery capital. The concept of social recovery emphasizes the relational processes of recovery.Design/methodology/approach– In-depth life history data were collected from 29 individuals who used heroin, cocaine, crack, or methamphetamine for at least five years, have less than a high-school education, and unstable employment and housing. Qualitative data were coded for social networks accessed throughout the life course, distinguished by bonding, bridging, and linking social capital.Findings– Social networks included drug treatment programs; non-drug-using family and friends; religious/spiritual groups; workplace networks; and social clubs/activities. Bonding and/or bridging social capital were acquired through treatment, family and friends, religious/spiritual groups, workplaces, and social clubs. Linking social capital was not acquired through any social network available, and many barriers to accessing mainstream social networks were found.Research limitations/implications– This is a small study conducted in the USA.Practical implications– Social recovery is proposed as an analytical tool as well as for developing prevention, intervention, and treatment strategies.Social implications– A greater focus on social recovery is needed to achieve sustained recovery for individuals lacking access to, and engagement in mainstream social networks.Originality/value– This paper further develops a new conceptual framework to use in recovery research and practice.
Gender, recovery and contemporary UK drug policy
Authors: Wincup Emma 
Published: February 2016

Purpose
– The purpose of this paper is to provide a gendered reading of the 2010 UK drug strategy and draw out the implications of the new recovery paradigm for female drug users.

Design/methodology/approach
– The paper explores the concept of recovery at a theoretical level, uncovering the taken-for-granted assumptions in the three overarching principles: freedom from dependence; well-being; and citizenship. It also analyses the available quantitative and qualitative evidence on women’s access to recovery capital to explore the role gender might play in the journey to recovery.

Findings
– Strategic thinking around recovery in the UK is largely silent on gender. However, close scrutiny of the available, albeit limited, evidence base on female drug users and feminist scholarship on the principles of well-being and citizenship suggests the need to understand recovery against a backdrop of the social and normative context of women’s lives.

Originality/value
– Recent analyses of contemporary UK drug policy have focused on the conflation of recovery with abstinence and the displacement of the harm reduction agenda. They have failed to draw out the implications for particular groups of drug users such as women. The pursuit of recovery-based drug policy is not peculiar to the UK so the paper offers a case study of its gendered application in a particular national context.
Third-party purchase: an empirical study of Chinese third-party logistics users
Authors: Shi Yangyan , Zhang Abraham , Arthanari Tiru , Liu Yanping 
Published: February 2016

Purpose– Third-party purchase (3PP) is a new value-added service offered by third-party logistics (3PL) providers. The purpose of this paper is to examine the perception of 3PP service from the perspective of 3PL users.Design/methodology/approach– The authors conducted a survey of Chinese 3PL users and received 242 usable responses. The authors then employed structural equation modeling to test the conceptual model.Findings– The authors found that the likelihood of 3PL users using a 3PP service is significantly associated with uncertainty, but not with asset specificity or frequency or transaction size. 3PP usage is significantly associated with value-to-client.Originality/value– This research is the first survey study of 3PP as a value-added service offered by 3PL providers, from the perspective of 3PL users. The findings suggest that 3PL users are very positive about the value of 3PP service. The 3PP market is still in its infancy but it has great potential, especially for commodity items that have less demand uncertainty.
Framework to improve performance through implementing Lean Six Sigma strategies to oil exporting countries during recession or depression
Authors: Chaurasia Basant , Garg Dixit , Agarwal Ashish 
Published: February 2016

Purpose– Today’s global business environment essential requirement to an industries reduction of wastes, reduction of variations, reduction of lead time and innovative feature quality product with minimum cost. That strives to improve customer satisfaction, break through strategies to solve problems with fastest process speed. Lean Six Sigma (LSS) strategy and framework can help during recession or upcoming recession to improve business excellencies and companies strategies against recession. The paper aims to discuss these issues.Design/methodology/approach– The paper followed views of authors, industrial experts from oil industries regarding LSS strategy, framework, comparative key factors of Lean and Six Sigma to overcome continuously decline oil prices globally. LSS strategy will proactively work as preventive tool for insipid economical growth of oil-exporting countries.Findings– To follow the LSS guidelines, oil-exporting countries can improve their business performance during ongoing oil price fall that may be influenced on gross domestic product of countries.Originality/value– The case study may provide some help to survive ongoing crisis of continuously fallen oil price that is highly problematic for oil-exporting countries.
After 20 years, what has remained of TQM?
Authors: Bernardino Lis Lisboa , Teixeira Francisco , Jesus Abel Ribeiro de , Barbosa Ava , Lordelo Maurício , Lepikson Herman Augusto 
Published: February 2016

Purpose
– Many Brazilian organizations have adopted total quality management (TQM). However, this model has lost prominence in academic and business environments. The purpose of this paper is to determine which aspects of TQM have endured over 20 years.

Design/methodology/approach
– With descriptive and exploratory objectives, this study used case studies of four companies that have adopted TQM, using temporal and comparative approaches in Brazil. The analysis explores the transcendence of disseminated aspects of TQM.

Findings
– The results revealed 19 percent disuse of TQM practices, 28 percent disuse of TQM tools and 57 percent disuse of TQM methodologies. However, the principles of TQM showed an average use of 96 percent, i.e. the predominant management philosophy remains part of the organizational environment of the companies. Although many practices, tools and methodologies are not described or named in the same way, their essence remains preserved and other practices, tools and methodologies have been incorporated into the automated systems of the companies.

Research limitations/implications
– Simple statistical tools are used as we use an exploratory and qualitative approach (with just four samples), making generalizations impossible. For future research the authors suggest a more quantitative approach using more complex statistical tools.

Originality/value
– The originality is demonstrated by the investigation of the cases of disuse, which contradicts most studies that analyze success stories. This paper aims to contribute to the understanding of how certain aspects of the models or “fads” survive or disappear over time.
ICT and sustainability in smart cities management
Authors: Bifulco Francesco , Tregua Marco , Amitrano Cristina Caterina , D'Auria Anna 
Published: February 2016

Purpose
– Contemporary debate is increasingly focused on ICT and sustainability, especially in relation to the modern configuration of urban and metropolitan areas in the so-called smartization process. The purpose of this paper is to observe the connections between smart city features as conceptualized in the framework proposed by Giffinger et al. (2007) and new technologies as tools, and sustainability as the goal.

Design/methodology/approach
– The connections are identified through a content analysis performed using NVivo on official reports issued by organizations, known as industry players within smart city projects, listed in the Navigant Research Report 2013.

Findings
– The results frame ICT and sustainability as “across-the-board elements” because they connect with all of the services provided to communities in a smart city and play a key role in smart city planning. Specifically, sustainability and ICT can be seen as tools to enable the smartization process.

Research limitations/implications
– An all-in-one perspective emerges by embedding sustainability and ICT in smart interventions; further research could be conduct through direct interviews to city managers and industry players in order to understand their attitude towards the development of smart city projects.

Practical implications
– Potential approaches emerging from this research are useful to city managers or large corporations partnering with local agencies in order to increase the opportunities for the long-term success of smart projects.

Originality/value
– The results of this paper delineate a new research path looking at the development of new models that integrate drivers, ICT, and sustainability in an all-in-one perspective and new indicators for the evaluation of the interventions.