bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using mitoribosomal profiling to investigate human mitochondrial translation
Authors: Gao Fei , Wesolowska Maria , Agami Reuven , Rooijers Koos , Loayza-Puch Fabricio , Lawless Conor , N. Lightowlers Robert , Chrzanowska-Lightowlers Zofia M. A. 
Published: January 2018

Background: Gene expression in human mitochondria has various idiosyncratic features. One of these was recently revealed as the unprecedented recruitment of a mitochondrially-encoded tRNA as a structural component of the large mitoribosomal subunit. In porcine particles this is mt-tRNAPhe whilst in humans it is mt-tRNAVal. We have previously shown that when a mutation in mt-tRNAVal causes very low steady state levels, there is preferential recruitment of mt-tRNAPhe. We have investigated whether this altered mitoribosome affects intra-organellar protein synthesis. Methods: By using mitoribosomal profiling we have revealed aspects of mitoribosome behaviour with its template mt-mRNA under both normal conditions as well as those where the mitoribosome has incorporated mt-tRNAPhe. Results: Analysis of the mitoribosome residency on transcripts under control conditions reveals that although mitochondria employ only 22 mt-tRNAs for protein synthesis, the use of non-canonical wobble base pairs at codon position 3 does not cause any measurable difference in mitoribosome occupancy irrespective of the codon. Comparison of the profile of aberrant mt-tRNAPhe containing mitoribosomes with those of controls that integrate mt-tRNAVal revealed that the impaired translation seen in the latter was not due to stalling on triplets encoding either of these amino acids. The alterations in mitoribosome interactions with start codons was not directly attributable to the either the use of non-cognate initiation codons or the presence or absence of 5’ leader sequences, except in the two bicistronic RNA units, RNA7 and RNA14 where the initiation sites are internal. Conclusions: These data report the power of mitoribosomal profiling in helping to understand the subtleties of mammalian mitochondrial protein synthesis. Analysis of profiles from the mutant mt-tRNAVal cell line suggest that despite mt-tRNAPhe being preferred in the porcine mitoribosome, its integration into the human counterpart results in a suboptimal structure that modifies its interaction with mt-mRNAs.
Financing Multiple Heterogeneous Suppliers in Assembly Systems: Buyer Finance vs. Bank Finance
Authors: Deng Shiming , Gu Chaocheng , Cai Gangshu (George) , Li Yanhai 
Published: January 2018

Buyer finance has been practiced by manufacturers/assemblers for years; however, few papers have investigated the efficacy of buyer finance in an assembly system with multiple suppliers. This paper fills the literature gap by comparing buyer finance with bank finance in a supply chain with one assembler and multiple heterogeneous capital-constrained component suppliers. We characterize the equilibrium solutions for different financing schemes (i.e., buyer finance, bank finance, and no finance). We show that in buyer finance the assembler should charge the suppliers the lowest possible interest rate, which may be even below its own unit capital opportunity cost, leading to interest losses in financing suppliers. However, the assembler can benefit more from enhanced inventory backup and lower component purchasing prices resulting from the low buyer-finance interest rate. We further compare the two financing schemes from the perspectives of the assembler, the borrowing and nonborrowing suppliers, and the whole supply chain. Our analysis reveals that the assembler may offer buyer finance even if its own unit capital opportunity cost is higher than the bank risk-free interest rate. We also demonstrate how the suppliers’ initial capitals, production costs, and their heterogeneities affect the assembler’s selection of the optimal financing scheme and identify the conditions under which buyer finance is better than bank finance for different parties in this assembly supply chain. The online appendix is available at https://doi.org/10.1287/msom.2017.0677 .
Risk assessment of M3Ms and decisions on ordering a CBCT and prescribing a coronectomy
Authors: Renton Tara 
Published: January 2018

Coronectomy is a procedure that is evidence based in order to prevent inferior alveolar nerve injury (IANI) related to surgery for high risk mandibular third molars (M3Ms). The justification for undertaking coronectomy rather than third molar removal is based upon risk assessment of the M3M, for which one has no clear parameters. There is international acceptance of this technique, however, there are many outstanding issues relating to the criteria for prescription, investigation and decision-making for this procedure including: risk factors for IAN injury/indications for cone beam CT scan (CBCT); indications for coronectomy as seen on plain films and then on to CBCT; complications/contra-indications of coronectomy; legal issues; and recommendations. Thus this personal opinion paper was aimed at highlighting the complexities around investigating, prescribing, patient consent and undertaking coronectomies, in order to assist the clinician in making surgical decisions faced with an ever changing evidence base and lack of specific criteria. CPD/Clinical Relevance: Third molar surgery is one of the most common surgical procedures undertaken on the NHS. Up to 48% of patients are reported to be at higher risk of inferior alveolar nerve injury after assessment with dental pantomograms, but the numbers do vary depending upon the patient cohort. This paper aims to unravel some of the conflicting evidence and attempts to provide some useful practical tips on the optimal management of these patients.
A case of poorly-differentiated squamous cell carcinoma following dental extractions
Authors: Kalra Aneesh , Huppa Christoph 
Published: January 2018

Gingival squamous cell carcinomas (SCC) are relatively rare and make up approximately 10% of oral squamous cell carcinomas. 1 The initial signs and symptoms of a gingival SCC can resemble common dental and periodontal infections and hence it is usually diagnosed late with a relatively poor prognosis. This report presents a case of a healthy 39-year-old patient who attended for routine wisdom teeth extractions, and returned to the emergency department complaining of progressive trismus and paraesthesia of the lower lip. A provisional diagnosis of osteomyelitis was made. However, further clinical, radiographic and histopathological investigations resulted in the diagnosis of poorly-differentiated SCC. CPD/Clinical Relevance: A series of misdiagnoses were made by specialists and by general dental and medical practitioners; this case highlights the importance of recognizing the signs and symptoms of oral carcinoma and appropriate subsequent management.
Above-Ground Biomass of Black Locust (Robinia pseudoacacia L.) Trees and Stands
Authors: Rédei Károly , Gál János , Keserű Zsolt , Antal Borbála 
Published: January 2018

Abstract
The increasing demand for forest products, diminishing forest land areas, and general concern about the long-term effects of deforestation have increased the need for multipurpose tree species with rapid growth rates. Consequently, information on renewable energy resources is becoming increasingly crucial, and forest biomass determination is becoming a significant part of forestry. Black locust (Robinia pseudoacacia L.) is a fast growing, nitrogen fixing, stress tolerant species with durable and high quality wood that can be used for many purposes including wall panelling; vine props; furniture; pulp and paper; animal feed stock; bee forage; and biomass energy. This article presents the above-ground biomass of black locust, both for individual trees and for stands. Information concerning wet and absolute dry wood for stem, merchantable (d1.3 > 5 cm) and small (d 1.3 < 5 cm) wood, and for other tree parts (foliage, bark) for individual trees and for black locust stands are detailed in dendromass tables by six yield classes.
Microwave synthesis of sulfanilic acid
Authors: Havlíček Jiří , Myška Karel , Tejchman Waldemar , Karásková Natálie , Doležal Rafael , Maltsevskaya Nadezhda V. , Kolář Karel 
Published: January 2018

AbstractSulfanilic acid represents an important substance, which is frequently utilized in the industry of azo dyes as well as in drug development of antimicrobials (e.g. of sulfonamides). Students can also meet with such type of compounds in chemistry labs, for example, when they estimate pH by methyl orange indicator or prepare Orange II for textile colouring. Both of these dyes are products of azo coupling of sulfanilic acid as diazonium salt withN,N-dimethylaniline or 2-naphthol, respectively. In the article, we focus on the synthesis of sulfanilic acid as a well-known experiment in the organic chemistry education. The synthesis was modified as the solvent free and microwave assisted experiment under semimicroscale conditions. That experiment is very convenient for the organic chemistry courses in the university or the high school teaching.
Helminth therapy: Advances in the use of parasitic worms against Inflammatory Bowel Diseases and its challenges
Authors: Maruszewska-Cheruiyot M. , Donskow-Łysoniewska K. , Doligalska M. 
Published: January 2018

Summary
Development of modern medicine and better living conditions in the 20th century helped in reducing a number of cases of infectious diseases. During the same time, expansion of autoimmunological disorders was noticed. Among other are Inflammatory Bowel Diseases (IBD) including ulcerative colitis and Crohn’s disease which are chronic and relapsing inflammation of the gastrointestinal tract. Absence of effective treatment in standard therapies effects the search for alternative opportunities. As per hygienic hypothesis increasing number of cases of autoimmune diseases is as a result of reduced exposure to pathogens, especially parasites. Thus, one of the promising remedial acts against IBD and other allergic and autoimmune disorders is “helminth therapy”. Cure with helminths seems to be the most effective therapy of IBD currently proposed. Helminth therapy focuses on advantageous results that have been obtained from the clinical trials, but its mechanisms are still unclear. Explanation of this phenomenon would help to develop new drugs against IBD based on helminth immunomodulatory molecules.
First report of the lesion nematodes: Pratylenchus brachyurus and Pratylenchus delattrei on tomato (Solanum lycopersicum L.) plants in Cape Verde
Authors: Flis Ł. , Dobosz R. , Rybarczyk-Mydłowska K. , Wasilewska-Nascimento B. , Kubicz M. , Winiszewska G. 
Published: January 2018

Summary
Roots of Solanum lycopersicum L. were collected in growing season of year 2015, on the island of Santiago in Cape Verde. Morphological, morphometric and molecular (18S rDNA and 28S rDNA) studies revealed the presence of Pratylenchus brachyurus and P. delattrei in root systems and root zones of tomato plants. To our knowledge, this is the first record of the occurrence of these nematode species in Cape Verde.
Optimum sample size to estimate mean parasite abundance in fish parasite surveys
Authors: Shvydka S. , Sarabeev V. , Estruch V. D. , Cadarso-Suárez C. 
Published: January 2018

SummaryTo reach ethically and scientifically valid mean abundance values in parasitological and epidemiological studies this paper considers analytic and simulation approaches for sample size determination. The sample size estimation was carried out by applying mathematical formula with predetermined precision level and parameter of the negative binomial distribution estimated from the empirical data. A simulation approach to optimum sample size determination aimed at the estimation of true value of the mean abundance and its confidence interval (CI) was based on the Bag of Little Bootstraps (BLB). The abundance of two species of monogenean parasitesLigophorus cephaliandL. mediterraneusfromMugil cephalusacross the Azov-Black Seas localities were subjected to the analysis. The dispersion pattern of both helminth species could be characterized as a highly aggregated distribution with the variance being substantially larger than the mean abundance. The holistic approach applied here offers a wide range of appropriate methods in searching for the optimum sample size and the understanding about the expected precision level of the mean. Given the superior performance of the BLB relative to formulae with its few assumptions, the bootstrap procedure is the preferred method. Two important assessments were performed in the present study: i) based onCIs width a reasonable precision level for the mean abundance in parasitological surveys ofLigophorusspp. could be chosen between 0.8 and 0.5 with 1.6 and 1x mean of theCIs width, and ii) the sample size equal 80 or more host individuals allows accurate and precise estimation of mean abundance. Meanwhile for the host sample size in range between 25 and 40 individuals, the median estimates showed minimal bias but the sampling distribution skewed to the low values; a sample size of 10 host individuals yielded to unreliable estimates.
Helminth fauna of Spiny Tailed Lizard,Darevskia rudis(Bedriaga, 1886) (Sauria: Lacertidae) from Turkey
Authors: Birlik S. , Yildirimhan H. Sami , Ilgaz Ç. , Kumlutaş Y. 
Published: January 2018

SummaryThe present study investigated the composition of helminth parasites ofDarevskia rudis,Spiny Tailed Lizard from Turkey. One hundred and two samples (49♀♀, 53♂♂) from the Tokat, Trabzon, Rize, Gümüşhane and Artvin Provinces were collected and examined for helminth parasites. New host and locality records were recorded. As a result of the present study, seven species of Nematoda,Skrjabinodon medinae,Spauligodonsp.,Spauligodon carbonelli,Spauligodon aloisei,Skrjabinelazia hoffmanni,Strongyloides darevsky,Oswaldocruzia filiformis; one species of Cestoda,Mesocestoidesspp. (tetrathyridium) and one species of AcanthocephalaSphaerirostris scanensiswere reported from the lizard samples.Sp. carbonelliandSphaerirostris scanensisare here recorded for the first time in Turkey.D. rudisis the new host recorded forSk. medinae,Spauligodonsp.,Sp. carbonelli,Sp. aloiseifrom Nematoda,Mesocestoidesspp. from Cestoda andSphaerirostris scanensisfrom Acanthocephala. This host has been studied for the first time for the helminth parasites from the Tokat and Gümüşhane Provinces. There is, to our knowledge, only one report of helminthes forD. rudisin Turkey.
Sensing Athletes: Sensory Dimensions of Recreational Endurance Sports
Authors: Groth Stefan , Krahn Yonca 
Published: January 2018

Abstract
Sport has become increasingly popular with recreational athletes over the last couple of decades. This has only gained minimal attention so far from scholars interested in the relations between recreational sports and everyday culture. With this paper, we seek to contribute to this field by scrutinising the sensory dimensions of recreational sport. Rather than probing into or highlighting isolated senses, we look at sensory dimensions understood as a combination of different, non-separable sensory experiences featured in recreational endurance sports. We are interested in how the senses play a role for recreational endurance athletes in running, triathlon and cycling both in training and competition. We start by examining how cultural and social dimensions are inextricably linked to doing sports. Secondly, we show how different configurations of the senses and their communicative mediation are contingent on sport disciplines, specific settings, technology, development and change as sensory careers over time. Thirdly, we discuss the kinaesthetic dimensions of doing sports in relation to the senses and the role of atmospheres. We conclude by arguing that highlighting specific senses by athletes is a cultural practice that calls for a holistic analysis of senses in sport, and outline some methodological implications for research on the senses.
PENGARUH MODEL PEMBELAJARAN PERSONAL (PERSONAL MODELS) TERHADAP KEPERCAYAAN DIRI DAN HASIL BELAJAR BERMAIN FUTSAL SISWA
Authors: Sumpena Asep 
Published: January 2018

Tujuan penelitian ini adalah untuk mengetahui apakah terdapat pengaruh yang signifikan model pembelajaran personal terhadap kepercayaan diri siswa dan hasil belajar bermain futsal siswa pada ekstrakurikuler futsal putra SMA Nasional Bandung. Metode yang digunakan dalam penelitian ini adalah eksperimen dengan menggunakan desain One Group Pretest-Posttest Design. Populasi dalam penelitian ini adalah siswa putra SMA Nasional Bandung yang mengikuti ekstrakurikuler futsal sebanyak 20 orang, sedangkan sampel dalam penelitian ini sebanyak 20 orang dengan menggunakan teknik pengambilan sampel yaitu sampel jenuh, yang berarti seluruh populasi dijadikan sampel. Instrumen kepercayaan diri menggunakan angket, sedangkan hasil belajar bermain menggunakan GPAI (Game Performance Assesment Instrument). Berdasarkan pengolahan dan analisis data yang diperoleh dapat diketahui nilai signifikansinya adalah 2,024 dengan hasil pengujian angket kepercayaan diri 2,512 dan hasil pengujian hasil belajar bermain 3,715. Karena nilai signifikansi lebih besar dari 2,024 maka Ho ditolak. Jadi dapat disimpulkan bahwa model pembelajaran personal (personal models) berpengaruh secara signifikan terhadap kepercayaan diri dan hasil belajar bermain futsal siswa.
Germination responses of seeds of Desmodium triflorum
Authors: Paudel Niroj , Rai Prakash Deep 
Published: January 2018

<p class="abstract"><strong>Background:</strong> Germination of <em>Desmodium triflorum</em> is used for the scarification using the acid is valuable for the different light condition.</p><p class="abstract"><strong>Methods:</strong> The sample was collected as four month of interval of time and the seed is treated with acids with different time. </p><p class="abstract"><strong>Results:</strong> seeds scarified with sulfuric acids for 10 min before sowing had better germination than those scarified for 5 and 15 min. Among them light qualities, red and white light had slightly promoted effect whereas blue light and dark condition had slightly negative effect on seed germination.</p><p><strong>Conclusions:</strong> In comparison to blue light and dark condition, red light and white light were promoted to percentage germination indicating the role of phytochrome in seed germination of <em>Desmodium triflorum</em>. </p>
The woman with habit of eating uncooked rice
Authors: Kalita Bitupan , Dihingia Sabita 
Published: January 2018

<p class="abstract"><span lang="EN-IN">Eating of non-nutritive substance (pica) is unusual in adult. Usually eating of non-nutritive substance in adult is associated with pregnancy, psychosis or mental retardation. In this case report we are presenting an adult female who presented with eating of uncooked rice regularly for last two years. Our patient is a housewife, non pregnant and mother of an eight year old girl. After receiving treatment with Fluvoxamine patient showed marked improvement, suggesting similarity between pica and obsessive compulsive disorder</span><span lang="EN-IN">. </span></p><p class="abstract"> </p>
Aspectos éticos en la investigación cualitativa con niños
Authors: Moscoso Loaiza Luisa Fernanda , Díaz Heredia Luz Patricia 
Published: January 2018

Introducción: La incorporación de los niños como participantes de estudios investigativos es una práctica más frecuente debido a la necesidad de conocer y entender su visión acerca de las experiencias de vida, planteando nuevos retos y responsabilidades que se centran principalmente en las consideraciones éticas y metodológicas de la investigación. Objetivo: Describir los aspectos éticos que deben ser tenidos en cuenta en la investigación cualitativa con niños. Metodología: Artículo de revisión con búsqueda sistemática en bases de datos, incluyendo artículos científicos, libros y literatura gris. Se seleccionó la información relevante en torno a ocho temas conforme al proceso investigativo. Resultados principales: La cuestión ética constituye un aspecto central en el momento de iniciar y desarrollar cualquier estudio investigativo, por lo que está presente desde su planteamiento hasta su finalización. Se abordan las consideraciones éticas que se encuentran implicadas desde la vinculación de los niños como participantes, hasta la obtención de la información y la socialización de los resultados. Conclusiones: El cumplimiento de los criterios de rigor metodológico como la dependencia, la credibilidad, la transferibilidad y la confirmación, aseguran la calidad de la investigación cualitativa con niños, permitiendo además, la adecuada aplicación de los principios éticos de beneficencia y no maleficencia, justicia, autonomía y confidencialidad.
Alguns limites e possibilidades da prática pedagógica no contexto escolar
Authors: Santos Adriana Regina de Jesus , Costa Rogerio da , Oliveira Claudia Chueire de , Luciano Helio Jose , Martins Nathalia 
Published: January 2018

O presente texto tem como finalidade identificar e analisar a concepção docente em relação aos principais aspectos que interferem de maneira positiva e negativa na prática pedagógica, levando em consideração o cotidiano escolar. Desta maneira, para este estudo utilizou-se pressupostos da abordagem qualitativa, amparando-se no método dialético. Assim, a pesquisa bibliográfica, documental e de campo compõem o conjunto de procedimentos investigativos. Outro ponto relevante é a compreensão referente aos limites da práxis pedagógica, considerando a relação entre o pensar e o construir de novas possibilidades referentes ao trabalho docente peculiar ao contexto em que está inserido. Assim, por meio deste estudo constatou-se que, torna-se imprescindível trabalhar com o pensar e o repensar das concepções sobre a prática docente relacionando-se a construção social da mesma, na qual é permeada de ideologias, valores e relações de poder que compõem o imaginário de uma dada sociedade.
Evaluation of using dietary supplements among polish adult people below and over 60 years of age
Authors: Suliga Katarzyna , Grzelak Teresa , Grupińska Joanna , Pelczyńska Marta , Sperling Marcelina , Czyżewska Krystyna 
Published: January 2018

Introduction. The population of elderly people is exposed to the development of disorders related to physiological ageing, as well as relatively common diseases occurring in the old age period. The gastrointestinal diseases, which reduce the absorption of many nutrients, are more frequent in the elderly compared to younger population.Material and Methods. In the study was attempted the assess of conditions of dietary supplementation by 60 years old people or older (60+). The comparisons of results were obtained with relation to young adults and middle aged persons (18–58 years). The survey was conducted with 368 adult, including 123 respondents over 60 years old and 245 younger people.Results. The study has been shown that dietary supplements were used by 64.2% of elderly people and 59.6% of younger respondents. The most common source of knowledge about dietary supplements in the elderly was a physician (40.7%) in contrast to younger population, where dominated the Internet (60.0%). The main reason of supplementation in the 60+ group was an enhancement the immune system, while in younger population it was important to improve the appearance of skin, hair and nails. The most common components of supplements, which were used in the elderly population, were vitamin C (32.5%) and magnesium (28.5%) compared to younger group where the most popular were vitamin D (22.5%) and magnesium (19.2%).Conclusions. The overuse of supplements, especially among the elderly, can lead to disability, therefore it is important to expand the education about side effects the improperly using of dietary supplements.