Abstract 1787: Adolescent boys and the human papillomavirus (HPV) - Geographical patterns of vaccination uptake
Authors: Geneus Christian J. , Mohammed Kahee A. , Tobo Betelihem B. , Adjei Boakye Eric , Osazuwa-Peters Nosayaba 
Published: July 2016

Abstract
INTRODUCTION
Human Papillomavirus (HPV) remains the most common sexually transmitted infection (STI) and is associated with multiple cancers. Previous research has examined HPV vaccine initiation and completion among girls. Among adolescent boys who are also at risk for contracting HPV, however, vaccine initiation and completion have not been widely explored.
OBJECTIVE
To examine predictors of HPV vaccine initiation and completion among boys in the United States.
METHODS
Analysis was conducted on 10,866 adolescent boys aged 13-17 using the 2014 National Immunization Survey-Teen. Our outcomes of interest, HPV vaccine initiation and completion, were measured using provider-verified vaccine history. Weighted multivariable logistic regression models assessed predictors of HPV vaccine initiation and completion.
RESULTS
Data stratified by geographic region showed that the prevalence of HPV vaccine initiation and completion ratio was lowest in the South: South (initiation: 38.82%, completion: 18.20%), Midwest (initiation: 38.15%, completion: 19.69%), West (initiation, 48.88%, completion: 26.12%), Northeast (initiation: 48.30%, completion: 26.96%).
Multivariable analysis of geographic patterns indicated that adolescent boys residing in the West had higher odds of vaccine initiation compared to those in the South (OR = 1.41; 95% CI: 1.08 - 1.83).On the other hand, the odds of vaccine completion were higher in adolescents residing both in the Northeast (OR = 1.46; 95% CI: 1.14 - 1.87) and West (OR = 1.42; 95% CI: 1.03 - 1.95) compared to adolescent boys residing in the South.
Adolescent boys who were recommended the HPV vaccine by a physician had 8.49 (95% CI; 7.03 - 10.26) and 5.97 (95% CI: 4.49 - 7.94) higher odds of initiation and completion, respectively. Compared to White adolescent boys, the odds of vaccine initiation (OR = 1.90; 95% CI: 1.47 - 2.48) and completion (OR = 1.49; 95% CI: 1.09 - 2.04) were higher amongHispanics boys. Moreover, boys aged 17 had higher odds of vaccine initiation compared to those who were 13 (OR = 1.41; 95% CI: 1.05 - 1.90). Finally, while mothers’ education partially influenced the odds of vaccine initiation in adolescent boys (&lt;12 years; OR = 2.053; 95% CI: 1.43 - 2.95), such was not significant in vaccine completion. Instead, higher odds of vaccine initiation among adolescent boys were associated with mothers who had two children aged&lt;18 years compared to one child (OR = 1.29; 95% CI: 1.07 - 1.56).
CONCLUSION
Our findings highlight the suboptimal HPV vaccine across the United States, as well as the sociodemographic disparities and geographic variation of HPV vaccine initiation and completion. Particularly among adolescent boys residing in the South, tailored interventions are needed to improve HPV vaccine uptake.
Citation Format: Christian J. Geneus, Kahee A. Mohammed, Betelihem B. Tobo, Eric Adjei Boakye, Nosayaba Osazuwa-Peters. Adolescent boys and the human papillomavirus (HPV) - Geographical patterns of vaccination uptake. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 1787.