bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disruption of exo-asteroids around white dwarfs and the release of dust particles in debris rings in co-orbital motion
Authors: Antoniadou Kyriaki I. , Veras Dimitri 
Published: September 2024

Context. Close to the Roche radius of a white dwarf (WD), an asteroid on a circular orbit sheds material that then adopts a very similar orbit. Observations of the resulting debris show a periodic behaviour and changes in flux on short timescales, implying ongoing dynamical activity. Additional encounters from other minor planets may then yield co-orbital rings of debris at different inclinations. The structure, dynamics, and lifetime of these debris discs remains highly uncertain, but is important for understanding WD planetary systems.
Aims. We aim to identify and quantify the locations of co-orbitals in WD–asteroid–dust particle three-body systems by exploring the influence of 1:1 resonant periodic orbits. We begin this exploration with co-planar and inclined orbits in the circular restricted three- body problem (CRTBP) and model the dynamical evolution of these exosystems over observable timescales. The mass ratio parameter for this class of systems (≈2 × 10−11) is one of the lowest ever explored in this dynamical configuration.
Methods. We computed the periodic orbits, deduced their linear stability, and suitably seeded the dynamical stability (DS) maps. We carried out a limited suite of N-body simulations to provide direct comparisons with the DS maps.
Results. We derive novel results for this extreme mass ratio in the CRTBP, including new unstable 3D families. We illustrate through the maps and N-body simulations where dust can exist in a stable configuration over observable timescales across a wide expanse of parameter space in the absence of strong external forces.
Conclusions. Over a timescale of 10 years, the maximum orbital period deviations of stable debris due to the co-orbital perturbations of the asteroid is about a few seconds. Unstable debris in a close encounter with the asteroid typically deviates from the co-orbital configuration by more than about 20 km and is on a near-circular orbit with an eccentricity lower than ≈0.01.
Behaarungszustand und Hautkolorit nach Brustrekonstruktion mittels
Deep Inferior Epigastric Perforator-Lappenplastik und anschließender
Rekonstruktion des Mamillen-Areolen-Komplexes
Authors: Bräuer Yi , Langer Jan , Lohmeyer Jörn Andreas , Deindl Philipp , Keck Maike 
Published: September 2024

Zusammenfassung
Einleitung Obwohl die DIEP (Deep inferior epigastric
perforator)-Lappenplastik der Goldstandard der Brustrekonstruktion ist, sind
Langzeitergebnisse bezüglich der postoperativen Behaarung und des Hautcolorits
des Lappens in der Literatur nur wenig beschrieben.
Methoden Patientinnen, die sich zwischen 2010 und 2019 einer
Brustrekonstruktion mittels DIEP-Lappenplastik und einer anschließenden
MAK-Rekonstruktion unterzogen haben, wurden zur Befragung und klinischen
Untersuchung in unsere Klinik eingeladen. Insgesamt wurden 781 Patientinnen
eingeladen. Die Befragung umfasste den BREAST-Q und einen studienspezifischen
Fragebogen. Die klinische Untersuchung umfasste spezifische Messungen der
postoperativen Behaarung und des Hautcolorits.
Ergebnisse Insgesamt wurden 179 Patientinnen untersucht, bei denen 203
Brüste rekonstruiert wurden. Nur Brüste mit einem oberflächlich sichtbaren
Lappen wurden in die weitere Auswertung aufgenommen. Insgesamt konnten 109
DIEP-Lappenplastiken und 77 MAK-Rekonstruktionen ausgewertet werden. In der von
den Patientinnen durchgeführten Umfrage berichteten 27,5% (30 von 109) über eine
zusätzliche Behaarung des Lappens und 62,4% (68 von 109) über einen Unterschied
in der Hautfarbe des Lappens im Vergleich zur umgebenden Haut. Bei der
klinischen Untersuchung wurde ein signifikanter Unterschied zwischen dem
Hautcolorit des Lappens im Vergleich zur umgebenden Haut und des Hautcolorits
der rekonstruierten MAK im Vergleich zur vorhandenen ursprünglichen MAK
festgestellt. In beiden Fällen erschienen die Rekonstruktionen deutlich “heller”
(P<0,05). Mit Hilfe des BREAST-Qs wurde kein signifikanter Unterschied der
Gesamtzufriedenheit zwischen Patientinnen mit und ohne Behaarung festgestellt.
Auch der Farbunterschied hatte keinen signifikanten Einfluss auf die
Zufriedenheit der Patientinnen.
Schlussfolgerung Eine zusätzliche Behaarung der Brust und ein
unterschiedlicher Hautcolorit sind relevant und sollten präoperativ kommuniziert
werden.
Forensic Age Determination Using MRI Scans of the Ankle: Applying Two Classifications to Assess Ossification
Authors: Wernsing Maximilian Frederic , Malokaj Valesa , Kunz Sebastian Nico , Beer Meinrad , Vogele Daniel 
Published: September 2024

AbstractIn forensic age determination, e.g. for legal proceedings, exceeded age limits may be relevant. To investigate age-related differences in skeletal development, the recommendations of the Study Group on Forensic Age Diagnostics (AGFAD) rely on imaging techniques using ionizing radiation (including orthopantomograms and radiographs of the hand). Vieth et al. and Ottow et al. have proposed MRI classifications for epi-/diaphyseal fusion of the knee joint to determine different age limits. The aim of the present study was to verify whether these two classifications could also be applied to MRI of the ankle.MRI images of the ankle from 333 patients (160 female, 173 male) ranging in age from 10 to 28 years were retrospectively analyzed. T1-weighted turbo spin-echo (TSE) sequences and T2-weighted fat-suppressed sequences were analyzed for the two classifications. The different ossification stages of the two classifications were determined and the corresponding chronological ages were assigned. In addition, gender-specific differences were analyzed. Intra- and inter-observer variability was determined using Cohen’s kappa.With the classification of Ottow et al., the completion of the 14th year of life could be determined in both sexes. With the classification of Vieth et al, the completion of the 14th year of life could be determined in both sexes and the 18th year of life in male patients. Intra-observer and inter-observer variability was very good and good, respectively (κ > 0.87 and κ > 0.72).In the present study, it was also possible to use both classifications for MRI of the ankle joint. The method offers the potential of an alternative or at least supplementary radiation-free assessment criterion in forensic age estimation.
Endovascular therapy in intermittent claudication: Impact of IVUS guidance on treatment decisions
Authors: Hartung Viktor , Augustin Anne Marie , Gruschwitz Philipp , Grunz Jan-Peter , Knarr Jonas , Kickuth Ralph 
Published: September 2024

AbstractConservative therapy is favored over revascularization for patients with peripheral arterial disease (PAD) and intermittent claudication (IC) owing to the better long-term results. The adjunctive use of intravascular ultrasound (IVUS) significantly improves endovascular therapy. However, data on IVUS and IC is scarce. Therefore, the aim of this investigation was to determine the safety and efficacy of IVUS in patients with IC and to evaluate discrepancies compared to angiography and potential consequences for treatment.This was a single-center prospective cohort study. Twenty patients with IC and femoropopliteal disease eligible for endovascular therapy were enrolled. Procedural data and discrepancies between IVUS and angiography were recorded.In total, 30 lesions were treated. IVUS-based measurements yielded substantially higher reference vessel diameters (RVD) and lesion lengths compared to DSA alone (RVD: 5.37 ± 0.71 mm vs. 4.74 ± 0.63 mm, p<.001, lesion length: 62.4 ± 41.4 mm vs. 42.18 ± 30.2 mm, p<.001). In 24 of 30 lesions (80%), a significant discrepancy in RVD (defined as difference >0.5 mm) and lesion length (defined as >20 mm) was determined between IVUS and standard DSA. Subsequently, IVUS assessment led to upsizing in 14 of 30 lesions (47%) and downsizing in 3 of 30 lesions (10%). On average, IVUS led to the selection of considerably larger balloons (5.25 ± 0.62 vs. 4.74 ± 0.63, p<.004) and device length (78.97 ± 44.19 mm vs. 42.18 ± 30.2, p<.001). Serious adverse events did not occur. Technical success was achieved in all cases.IVUS is safe and provides advantages regarding the evaluation of IC by depicting RVD and lesion length more reliably than standard DSA. More precise assessment of lesions resulted in the use of significantly larger devices.Hartung V, Augustin AM, Gruschwitz P et al. Endovascular therapy in intermittent claudication: Impact of IVUS guidance on treatment decisions. Fortschr Röntgenstr 2024; DOI 10.1055/a-2379-8857
A Practical Guide to SuFEx Chemistry: An Overview of S(VI)-SuFEx Linkers and Their Reactivity
Authors: Serbetci Defne , Marraffa Laura , Luisi Renzo , Natho Philipp , Andresini Michael 
Published: September 2024

AbstractSulfur(VI)–fluoride exchange (SuFEx) is a second generation, metal-free click chemistry concept introduced by Sharpless in 2014. Since the introduction of the concept, a large variety of synthetic methodologies to S(VI)-SuFEx hubs, and their derivatization with oxygen-, nitrogen-, and carbon-based nucleophiles have been developed. Herein, we provide a concise and practical overview for their preparation, SuFExability, inclusive of which substituents are tolerated. The stereoselective synthesis of aza-derivatives is also discussed.1	Introduction2	Synthesis of SuFEx Hubs2.1	Sulfonyl Fluorides2.2	Fluorosulfates2.3	Sulfamoyl Fluorides2.4	Sulfonimidoyl Fluorides2.5	Sulfuramidimidoyl Fluorides and Sulfurofluoridoimidates2.6	Sulfondiimidoyl Fluorides3	Reactivity of SuFEx Hubs3.1	Reactivity of Sulfonyl Fluorides3.2	Reactivity of Fluorosulfates3.3	Reactivity of Sulfamoyl Fluorides3.4	Reactivity of Sulfonimidoyl Fluorides3.5	Reactivity of Sulfurofluoridoimidates3.6	Reactivity of Sulfondiimidoyl Fluorides4	Stereochemical Considerations in SuFEx Chemistry5	Conclusion and Outlook
Platinum-Catalyzed Deoxygenation of N-Acyloxyamines
Authors: Ali Kashif , Cho Eun Jin 
Published: September 2024

AbstractWe report a Pt-catalyzed double deoxygenative transformation of N-acyloxyamines, employing PtCl2 catalyst without external ligand under mild conditions. This method facilitates efficient C–N bond formation and can be used to synthesize a broad spectrum of alkylated secondary and tertiary amines with excellent yields. The adaptability and effectiveness of this approach highlight the potential of platinum catalysis to extend beyond traditional synthetic boundaries.
The Influence of Preimplant Balancing on Manipulation under Anesthesia Rates following Imageless Robotic-Assisted Total Knee Arthroplasty
Authors: Butler Justin T. , Stegelmann Samuel D. , Davis Trent , Singleton Amy , Ostlie Hunter , Miller Richard , Davis Kirk 
Published: September 2024

AbstractAcquired idiopathic stiffness (AIS) following total knee arthroplasty (TKA) often requires manipulation under anesthesia (MUA). Robotic-assisted TKA (RA-TKA) systems provide gap balance templates for objective correlation with the rate of AIS. The purpose of this study was to assess intraoperative balancing parameters that were associated with MUA utilizing an “anatomical” implant design.We performed a retrospective chart review of 265 imageless RA-TKA procedures performed by R.M. and K.D. between 2018 and 2020. The primary outcome for AIS or clinically significant “arthrofibrosis” was MUA. Patient intraoperative gap planning data were examined for association.The rate of MUA was 8.7% (23/265), which was performed at a mean follow-up time of 75.9 ± 32.2 days. The lateral to medial gap difference in extension was significantly less in patients requiring MUA (odds ratio [OR] = 0.86, 95% confidence interval [CI], 0.75–0.99) (p = 0.034). Significantly less preoperative varus mechanical axis was associated with knees requiring MUA (1.83° vs. 4.04°, OR = 1.09, 95% CI, 1.00–1.19). Decreased templated mechanical axis correction was associated with MUA (2.09° vs. 4.75°, p < 0.0001).A tighter lateral-to-medial gap in extension, less preoperative varus, and smaller templated mechanical axis corrections were associated with increased rates of MUA.
Recent Advances in Diazophosphonate Chemistry: Reactions and Transformations
Authors: Peng Yungui , Ullah Saif , Hussain Zulfiqar 
Published: September 2024

AbstractDiazophosphonates function as indispensable synthetic intermediates within the domain of organic chemistry, serving as precursors for a diverse range of molecules, with potential applications as bioactive compounds. α-Diazomethylphosphonates showcase expansive reactivity and elevated levels of enantioselectivity in asymmetric transformations, especially in conjunction with suitable catalyst systems. This review compiles the latest advancements in diazophosphonate chemistry from 2016 to 2024, highlighting their reactivity and transformative potential in organic synthesis. Diazophosphonates, regarded as revolutionary compounds, exhibit unique attributes as carbene precursors, driving diverse chemical reactions such as [3+2] cycloaddition, asymmetric [3+2] cycloaddition, asymmetric [3+3] cycloaddition, and asymmetric substitution reactions. Their adaptability in functional group conversions underscores their pivotal role in various synthetic methodologies. The review highlights the growing interest in diazophosphonate reactions among synthetic chemists, fostering novel synthetic strategies and expanding their application horizons. The multifaceted utility of diazophosphonates as reagents, synthetic intermediates, precursors, and catalysts underscores their significance in modern organic chemistry and pharmaceutical applications, prompting further exploration into this dynamic field.1	Introduction2	[3+2] Cycloaddition Reactions3	Asymmetric [3+2] Cycloaddition Reactions4	Asymmetric [3+3] Cycloaddition Reactions5	Asymmetric Substitution Reactions6	Diazophosphonates as Carbene Precursors7	Diazophosphonates in the Chemistry of Fluorinated Compounds8	Other Reactions9	Future Directions10	Conclusion
Evaluation of Mobile Apps Used among Medical Students for Learning and Education: A Mixed-Method Concurrent Triangulation Approach
Authors: Almulhem Jwaher A. , Aldekhyyel Raniah N. , Binkheder Samar 
Published: September 2024

Abstract
Background The use of medical mobile applications (apps) to enhance learning is widespread in medical education. Despite the large number of medical apps used among medical students for learning, many apps have not been evaluated using validated instruments. Finding relevant and valuable apps for student learning might be difficult.
Objective The objective is to evaluate four medical apps (AMBOSS, ISABEL, Medscape, and OSMOSIS) in improving just-in-time learning among medical students using the Mobile App Rubric for Learning (MARuL).
Methods We employed a mixed-method concurrent triangulation approach. The study included the entire population of third-year medical students at King Saud University. These students were selected due to their use of medical apps for learning for at least 1 year. The MARuL, which consists of four measures: Teaching and Learning, User-centered, Professional, and Usability, was electronically distributed to medical students for assessment. Descriptive statistics were calculated for all measures, and thematic content analysis was applied to analyze responses to open-ended questions.
Results The MARuL evaluation revealed that the OSMOSIS app received the highest Usefulness for Learning Score, with Usability Measures being the most positively evaluated measure. Following was the AMBOSS app, which scored highest in the Professional Measures, along with the Medscape and the ISABEL apps. We identified several key features and challenges from analyzing students' responses to open-ended questions regarding the use of the four medical apps. These included six themes: (1) study support and learning tools, (2) comprehensive information, (3) interface experience, (4) cost and accessibility issues, (5) learning methods and content limitations, and (6) user experience and technical issues.
Conclusion Equipping medical students with the ability to evaluate and choose medical apps that facilitate just-in-time learning is a crucial element that should be integrated into the medical curriculum.
Phenotypic Heterogeneity in ORAI-1-Associated Congenital Myopathy
Authors: Baskar Dipti , Vengalil Seena , Polavarapu Kiran , Preethish-Kumar Veeramani , Arunachal Gautham , Sukrutha Ramya , Bardhan Mainak , Huddar Akshata , Unnikrishnan Gopikrishnan , Kulkarni Girish Baburao , Chickabasaviah Yasha T. , Kumar Rashmi Santhosh , Nalini Atchayaram , Nashi Saraswati 
Published: September 2024

Abstract
Introduction ORAI-1 is a plasma membrane calcium release-activated calcium channel that plays a crucial role in the excitation–contraction of skeletal muscles. Loss-of-function mutations of ORAI-1 cause severe combined immunodeficiency, nonprogressive muscle hypotonia, and anhidrotic ectodermal dysplasia. Autosomal dominant gain-of-function mutation causes Stormorken's syndrome, which includes tubular aggregate myopathy along with bleeding diathesis.
Methods This is a description of a genetically confirmed case of ORAI-1-associated myopathy with clinical, histopathological, and imaging characteristics and a detailed literature review.
Results We report an 18-year-old woman who presented with 2-and-a-half year history of slowly progressive proximal lower limb weakness and ophthalmoparesis. Her serum creatine kinase levels were normal. Magnetic resonance imaging of the muscle showed predominant fatty infiltration of the glutei and quadriceps femoris. Histopathological analysis of muscle biopsy was suggestive of congenital fiber-type disproportion (CFTD). Clinical exome sequencing showed novel homozygous nonsense pathogenic variant NC_000012.12 (NM_032790.3): c.205G > T (p.Glu69Ter) in ORAI-1 gene.
Conclusion This report expands the phenotypic spectrum of ORAI-1-related myopathy to include congenital myopathy—CFTD with ophthalmoparesis, a novel manifestation.
Healthy sexuality—not sexual health: for the sexual subject
Authors: Čierna Andrea , Bianchi Gabriel 
Published: September 2024

Abstract
The aim of this paper is to defend the emerging conceptualization of healthy sexuality (Bianchi in Figurations of Human Subjectivity: A Contribution to Second-Order Psychology. Springer, Berlin, 2020) against the traditional authoritative concept of sexual health as defined by the WHO. Becoming a sexual subject means following a sexual trajectory with episodes of one’s own bodily experiences, genital satisfaction, intimate attachment, acceptance of sexual identity, sexual pleasure, mutual sexual satisfaction and planned parenthood. In each of these episodes, the individual may experience feelings of pressure, fear, shame, pain and/or joy and pleasure. The extent to which the subject has a healthy sexuality depends on whether these feelings/emotions facilitate or inhibit healthy sexuality. The concept of healthy sexuality runs counter not only to quantitative statistical demographic measures of sexual health, but also to the existing arsenal of sexology questionnaires. Qualitative empirical research is being conducted into the facilitators and inhibitors of a healthy sexuality (in the first author’s PhD research).
Mouth-controlled mouse for quadriplegic disabled people: System design and validation
Authors: Lin Sheng-Yuan , Tai Cheng-Chi , Lu Tsui-Ping , Wen Miin-Jye 
Published: September 2024

Disabled people with a high cervical cord injury or quadriplegia face difficulties when controlling a computer. This study presents a digital mouth-controlled mouse-control aid called the bite-press mouth-controlled mouse (BPMCM) to replace the traditional computer mouse. The BPMCM is equipped with a joystick and micro switch, and the disabled person uses neck and head movements to push the joystick and control the cursor position while the three mouse functions (i.e., left-click, right-click, and drag) are activated by bite-pressing for different time intervals. The proposed design eliminates the sip-and-puff technique and the need to recite orders for reduced adaptation time and increased convenience. Furthermore, this design supports plug-and-play and hot plugging in modern mainstream operating systems that can often be directly operated via mouse functions. Experimental results demonstrated that disabled people using a BPMCM were as capable as healthy participants in operating a computer, with both experiments completed within 5 min, and voluntary disabled people immediately adapted to the BPMCM. The proposed design is expected to allow disabled people to operate computers at the same level as healthy participants. The BPMCM also required only half the physical exertion of other mouth-controlled mouse-control aids that require orders to be recited.
Simple experiment design for impulsive force measure at hammer and nail collisions
Authors: Untoro Nur , Ramdhan Muhammad 
Published: September 2024

Abstract
For approximately 2400 years BC, carpenters have been using hammers to nail wood. The reason for this method is unclear and evaluations of its effectiveness should not be made without proper research. Therefore, this study aims to develop a force-measuring instrument to analyze the impulsive forces produced during hammer strokes on nails. The measurement process is based on the laws of conservation of momentum and mechanical energy and the work-energy principle. The apparatus was constructed using a PVC pipe fitted with a rope pulley and load. The measurements were taken by dropping the mass onto nails embedded in the wooden specimens of keruing, teak, mahogany, and pine. The findings demonstrate that the impulsive force involved in driving nails into wood remains constant. This force is not influenced by the speed of the hammer swing, but rather by the wood’s level of hardness and penetration depth. Using harder wood results in a greater impulsive force, therefore, driving nails becomes more efficient in securing them into the wood.
Neural networks assisted Metropolis-Hastings for Bayesian estimation of critical exponent on elliptic black hole solution in 4D using quantum perturbation theory
Authors: Hatefi Armin , Hatefi Ehsan , Lopez-Sastre Roberto J. 
Published: September 2024

Abstract
It is well-known that the critical gravitational collapse produces continuous self-similar solutions characterized by the Choptuik critical exponent, γ. We examine the solutions in the domains of the linear perturbation equations, considering the numerical measurement errors. Specifically, we study quantum perturbation theory for the four-dimensional Einstein-axion-dilaton system of the elliptic class of SL(2,ℝ) transformations. We develop a novel artificial neural network-assisted Metropolis-Hastings algorithm based on quantum perturbation theory to find the distribution of the critical exponent in a Bayesian framework.
Unlike existing methods, this new probabilistic approach identifies the available deterministic solution and explores the range of physically distinguishable critical exponents that may arise due to numerical measurement errors.