bluuebunny/crossref_metadata_2025_split huggingface dataset:
hdnom: Building Nomograms for Penalized Cox Models with High-Dimensional Survival Data
Authors: Xiao Nan , Xu Qing-Song , Li Miao-Zhu 
Published: August 2016

AbstractSummaryWe developed hdnom, an R package for survival modeling with high-dimensional data. The package is the first free and open-source software package that streamlines the workflow of penalized Cox model building, validation, calibration, comparison, and nomogram visualization, with nine types of penalized Cox regression methods fully supported. A web application and an online prediction tool maker are offered to enhance interac-tivity and flexibility in high-dimensional survival analysis.AvailabilityThe hdnom R package is available from CRAN:https://cran.r-project.org/package=hdnomunder GPL. The hdnom web application can be accessed athttp://hdnom.io. The web application maker is available fromhttp://hdnom.org/appmaker. The hdnom project website:http://hdnom.org.Contactqsxu@csu.edu.cnormiaozhu.li@duke.edu
Using null models to infer microbial co-occurrence networks
Authors: Connor Nora , Barberán Albert , Clauset Aaron 
Published: August 2016

AbstractAlthough microbial communities are ubiquitous in nature, relatively little is known about the structural and functional roles of their constituent organisms’ underlying interactions. A common approach to study such questions begins with extracting a network of statistically significant pairwise co-occurrences from a matrix of observed operational taxonomic unit (OTU) abundances across sites. The structure of this network is assumed to encode information about ecological interactions and processes, resistance to perturbation, and the identity of keystone species. However, common methods for identifying these pairwise interactions can contaminate the network with spurious patterns that obscure true ecological signals. Here, we describe this problem in detail and develop a solution that incorporates null models to distinguish ecological signals from statistical noise. We apply these methods to the initial OTU abundance matrix and to the extracted network. We demonstrate this approach by applying it to a large soil microbiome data set and show that many previously reported patterns for these data are statistical artifacts. In contrast, we find the frequency of three-way interactions among microbial OTUs to be highly statistically significant. These results demonstrate the importance of using appropriate null models when studying observational microbiome data, and suggest that extracting and characterizing three-way interactions among OTUs is a promising direction for unraveling the structure and function of microbial ecosystems.Author SummaryMicrobes are ubiquitous in the environment. We know that microbial communities – the groups of microbes that live together, interact, and depend on one another – vary across environments. Multiple processes, ranging from competition between microbes to environmental stress, are believed to alter microbial community composition. Here, we describe a set of statistical techniques that can more accurately identify the underlying taxa relationships that structure the observed abundances of microbes across habitats. Using a large data set of soil samples collected across North and South America, we both illustrate the statistical artifacts that incorrect methods can introduce and describe proper techniques based on appropriate null models for studying how the abundances of taxa vary across soil samples. These tools improve our ability to distinguish ecologically meaningful interactions from simple statistical noise in such observational data. Our application of these tools suggests some previous claims about the network structure of microbial communities may be statistical artifacts. Furthermore, we find that three-way interactions among microbial taxa are significantly more common than we would expect at random, and thus may provide a novel means for identifying ecologically meaningful interactions.
Simulations of biomass dynamics in community food webs
Authors: Delmas Eva , Brose Ulrich , Gravel Dominique , Stouffer Daniel B. , Poisot Timothée 
Published: August 2016

Food webs are the backbone upon which biomass flows through ecosystems. Dynamical models of biomass can reveal how the structure of food webs is involved in many key ecosystem properties, such as persistence, stability, etc.In this contribution, we present BioEnergeticFoodWebs, an implementation of Yodzis & Innes (1992) bio-energetic model, in the high-performance computing language Julia.We illustrate how this package can be used to conduct numerical experiments in a reproducible and standard way.A reference implementation of this widely used model will ease reproducibility and comparison of results across studies.
Insects and associated arthropods analyzed during medicolegal death investigations in Harris County, Texas, USA: January 2013-April 2016
Authors: Sanford Michelle R. 
Published: August 2016

ABSTRACTThe application of insect and arthropod information to medicolegal death investigations is one of the more exacting applications of entomology. Historically limited to homicide investigations, the integration of full time forensic entomology services to the medical examiner’s office in Harris County has opened up the opportunity to apply entomology to a wide variety of manner of death classifications and types of scenes to make observations on a number of different geographical and species-level trends in Harris County, Texas, USA. In this study, a retrospective analysis was made of 203 forensic entomology cases analyzed during the course of medicolegal death investigations performed by the Harris County Institute of Forensic Sciences in Houston, TX, USA from January 2013 through April 2016. These cases included all manner of death classifications, stages of decomposition and a variety of different scene types that were classified into decedents transported from the hospital (typically associated with myiasis or sting allergy; 3.0%), outdoor scenes (32.0%) or indoor scenes (65.0%). Ambient scene air temperature at the time scene investigation was the only significantly different factor observed between indoor and outdoor scenes with average indoor scene temperature being slightly cooler (25.2°C) than that observed outdoors (28.0°C). Relative humidity was not found to be significantly different between scene types. Most of the indoor scenes were classified as natural (43.3%) whereas most of the outdoor scenes were classified as homicides (12.3%). All other manner of death classifications came from both indoor and outdoor scenes. Several species were found to be significantly associated with indoor scenes as indicated by a binomial test, includingBlaesoxipha plinthopyga(Sarcophagidae), all Sarcophagidae includingB.plinthopyga,Megaselia scalaris(Phoridae),Synthesiomyia nudiseta(Muscidae) andLucilia cuprina(Calliphoridae). The only species that was a significant indicator of an outdoor scene wasLucilia eximia(Calliphoridae). All other insect species that were collected in five or more cases were collected from both indoor and outdoor scenes. A species list with month of collection and basic scene characteristics with the length of the estimated time of colonization is also presented. The data presented here provide valuable casework related species data for Harris County, TX and nearby areas on the Gulf Coast that can be used to compare to other climate regions with other species assemblages and to assist in identifying new species introductions to the area. This study also highlights the importance of potential sources of uncertainty in preparation and interpretation of forensic entomology reports from different scene types.
Prototyping ofBacillus megateriumgenetic elements through automated cell-free characterization and Bayesian modelling
Authors: Moore Simon J. , MacDonald James T. , Weinecke Sarah , Kylilis Nicolas , Polizzi Karen M. , Biedendieck Rebekka , Freemont Paul S. 
Published: August 2016

AbstractAutomation and factorial experimental design together with cell-freein vitrotranscription-translation systems offers a new route to the precise characterization of regulatory components. This now presents a new opportunity to illuminate the genetic circuitry from arcane microbial chassis, which are difficult to assessin vivo. One such host,Bacillus megaterium, is a giant microbe with industrial potential as a producer of recombinant proteins at gram per litre scale. Herein, we establish aB. megateriumcell-free platform and characterize a refactored xylose-repressor circuit using acoustic liquid handling robotics to simultaneously monitor 324 reactionsin vitro. To accurately describe the system, we have applied a Bayesian statistical approach to infer model parameters by simultaneously using information from multiple experimental conditions. These developments now open up a new approach for the rapid and accurate characterization of genetic circuitry using cell-free reactions from unusual microbial cell chasses for bespoke applications.
Growth Factors do not regulate Golgi Complex-to-ER relocation of GalNAc-Ts in HeLa cells
Authors: Herbomel Gaetan G. , Rojas Raul E. , Tran Duy T. , Ajinkya Monica , Beck Lauren , Tabak Lawrence A. 
Published: August 2016

AbstractMucin-type O-glycosylation is initiated by the UDP-GalNAc polypeptide:N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Their activity results in the GalNAc α1-O-Thr/Ser structure, termed the Tn antigen, which is further decorated with additional sugars. In neoplastic cells, the Tn antigen is often overexpressed. Because O-glycosylation is controlled by the activity of GalNAc-Ts, their regulation is of great interest. Previous reports suggest that growth factors, EGF or PDGF, induce Golgi complex-to-endoplasmic reticulum (ER) relocation of both GalNAc-Ts and Tn antigen in HeLa cells, offering a mechanism for Tn antigen overexpression termed “GALA”. However, we were unable to reproduce these findings. Upon treatment of HeLa cells with either EGF or PDGF we observed no change in the co-localization of endogenous GalNAc-T1, GalNAc-T2 or Tn antigen with the Golgi complex marker TGN46. There was also no enhancement of localization with the ER marker calnexin. We conclude that growth factors do not cause redistribution of GalNAc-Ts from the Golgi complex to the ER in HeLa cells.
The negative synergistic effect of internationalization and corporate social responsibility on US restaurant firms’ value performance
Authors: Jung SoYeon , Lee Seoki , Dalbor Michael 
Published: August 2016

PurposeThe purpose of the current study is to investigate the possible existence of a synergistic effect of internationalization and corporate social responsibility (CSR) on a firm’s value performance.Design/methodology/approachTo empirically test the argument, this study analyzed data from 40 US-based publicly traded restaurant companies (251 observations) from 2000 to 2011 by performing a two-way fixed-effects model.FindingsThis study’s findings support the hypothesis that when implemented simultaneously, internationalization and CSR have a negative synergistic impact on a restaurant firm’s value performance.Practical implicationsRestaurant managers might need to inquire thoroughly into the timing and content of CSR investment strategies while entering into new international markets. Restaurant executives may additionally need to focus more on effective risk management than other issues (e.g. growth or reputation) when developing both internationalization and CSR strategies simultaneously.Originality/valueBy suggesting and demonstrating a negative synergistic effect of internationalization and CSR on a firm’s value, this study presents new and unique insights into previous research regarding the combined effect of the two strategies.
Social media communication strategies
Authors: Floreddu Paola Barbara , Cabiddu Francesca 
Published: August 2016

PurposeWhile a great amount of literature has focused on the relationship between communication strategies and corporate reputation, there is no systematic research on the different kinds of social media communication strategies. Based on the corporate reputation and social media literature, this paper aims to contribute to this gap in the research in two main ways. First identifying which social media communication strategy is more effective with contrasting levels of reputations; second, analyzing the differences between high- and low-reputation companies with respect to their ability to use corporate communication.Design/methodology/approachThis paper uses a longitudinal explorative multiple-case study and theoretical sampling. The research setting is the Italian insurance context. The focus of this analysis on one medium, Facebook, because it is the most exploited in the context of the Italian insurance sector.FindingsSix complementary social media communication strategies were identified: egocentric, conversational, selective, openness, secretive and supportive. The results also reveal distinct ways in which high-, medium- and low-reputation companies’ utilize the six complementary strategies of communications.Research limitations/implicationsThe study is based on a single industry and on one single geographical market, and care should thus be taken in generalizing the findings to other contexts. Therefore emerges the opportunity to broaden this research to other similar service sector, such as banking, to assess and generalize the results obtained. In addition, a possible direction of research, especially from a methodological standpoint, should investigate companies from different countries. Such a comparative study would examine in depth whether and to what extent the institutional framework may impact on communication strategies implemented by companies. This study only analyzed one social media (Facebook); hence, we cannot draw firm conclusions about what may constitute a successful social media communication strategy.Practical implicationsFrom this study, managers can learn how to combine the six communication strategies to have an effective impact on the corporate reputation. They can also learn how the number of interactions and the time taken to respond to questions from customers improve the corporate reputation and provide communication that is more effective.Originality/valueThis research extends the previous literature on corporate reputation and corporate communication, showing the relationship between them in a social media context and providing different strategies of managing this combination.
Attraction during the service encounter: examining the other side of the coin
Authors: Kuppelwieser Volker G. , Touzani Mourad 
Published: August 2016

PurposeThe existing literature dealing with attractiveness during a service encounter focuses on employee attractiveness and its consequences. This paper aims to consider the other side of the coin by focusing on customers’ attractiveness.Design/methodology/approachOn the basis of two studies, this paper presents and tests a model explaining the specific role that employee social attraction plays in customer service perception and satisfaction judgment.FindingsIt suggests that the appraisal of customers’ physical attractiveness and homophily may lead to situations in which employees are socially attracted to customers, thus influencing customer service perception.Originality/valueConsequently, this research provides insights into the role of attraction determinants in a service context. In addition, it demonstrates how employees’ social attraction is triggered in a service context. The findings contribute to satisfaction research by extending prior research perceptions on dyadic service encounters and examining both employee attitude and customer perceptions in service interactions.
Testing additive versus interactive effects of person-organization fit and organizational trust on engagement and performance
Authors: Alfes Kerstin , Shantz Amanda , Alahakone Ratnesvary 
Published: August 2016

PurposeTo date, most research has assumed an additive relationship between work-related predictors and engagement. The purpose of this paper is to contribute to the refinement of engagement theory by exploring the extent to which two predictors – person-organization fit and organizational trust – interact to influence employees’ engagement, which in turn, positively influences their task performance.Design/methodology/approachA test of moderated mediation was conducted using survey data collected from 335 employees and matched performance records from the Human Resource department in a support services organization in the UK.FindingsEngagement was best predicted by the interactive model, rather than the additive model, as employees who felt a close fit with their organization and who trusted their organization were most engaged with their work. Further, engagement mediated the relationship between the interaction and task performance.Originality/valueThis paper contributes to a refinement of engagement theory by presenting and testing a model that explains the synergistic effect of work-related factors on engagement.
The occurrence of demotions regarding job level, salary and job authority
Authors: Verheyen Tanja , Deschacht Nick , Guerry Marie-Anne 
Published: August 2016

PurposeThe purpose of this paper is to determine the occurrence of job level, salary and job authority demotions in the workplace through the analysis of Belgian Statistics on Income and Living Conditions (SILC)-data of 2007-2011.Design/methodology/approachThree hypotheses are tested:H1: there is a gender inequality in job authority demotions.H2: the level of education and the probability of being subject to a job level, salary or job authority demotion are negatively correlated.H3: age is negatively correlated with job level, salary or job authority demotion probabilities. The cross-sectional data of the SILC cover a specific time period with data on inter alia living conditions. The longitudinal data give information on inter alia income and non-monetary variables over a period of four years. The authors estimate multivariate regression models for binary demotion variables. These analyses allow the authors to estimate the odds of being demoted. The authors discuss the demotion rates, the bivariate correlations and the regression analysis.FindingsThe data analysis result in the fact that base salary demotions are not commonly applied as literature and the Belgian law on salary protection endorses. Fringe benefits demotions, as for instance the abolition of a company car or a bonus are, however, more frequent. There is a gender gap with regard to job authority demotion. Highly educated respondents are less confronted with job authority demotions. Age is negatively correlated with base salary/fringe benefits or job authority demotion probabilities, but not with job-level demotions.H1is thus confirmed.H2andH3only partly confirmed.Research limitations/implicationsSeveral analyses were restricted because the EU-SILC did not question all dimensions of demotion in detail.Originality/valueThis study contributes to the scarce literature on demotion and to empirical studies on demotions regarding job level, salary and job authority.
An exploratory study of jobseekers’ decision-making styles, recruitment information sources and organisational attractiveness
Authors: Liu Yu-Lun , Keeling Kathleen A. , Papamichail K. Nadia 
Published: August 2016

PurposeThe purpose of this paper is to investigate the consequences of jobseeker decision-making style on information search behaviour, information evaluation and perceptions of organisational attractiveness (OA). In this study, the authors assess whether, when presented with a realistic job information searching scenario of receiving basic job information from a typical formal short job advertisement, maximisers and satisficers differ on need for further information and evaluation of further information from informal information sources in relation to valence and tie strength.Design/methodology/approachA scenario-based experiment was conducted on 280 participants from the USA, with work experience in retail, using Amazon Mechanical Turk.FindingsThe results show that, compared to satisficers, significantly more maximisers chose to search for further information about the company/vacancy after receiving a typical short advertisement message. Furthermore, the results highlight the moderating effects of decision-making style (maximiser vs satisficer), tie strength (strong-tie vs weak-tie provider) and message valence (positive vs negative) on jobseekers’ perceived OA.Practical implicationsCompanies seeking to increase their candidate pool should consider accommodating the different decision-making styles of jobseekers by carefully designing the content of recruitment information and utilising recruitment information sources. Although conducted in just one sector, the ubiquity of the maximiser/satisficer decision-making style implies further research to assess the implications for other sectors.Originality/valueResearch on decision-making style in recruitment is relatively limited. This study demonstrates the differences between maximisers and satisficers in terms of job-related information needs, and the evaluation of the source/content, when searching for a retail trade job.
The MTMM matrix approach: implications for HRM research
Authors: Hamdani Maria Riaz , Valcea Sorin , Buckley Michael Ronald 
Published: August 2016

Purpose
The purpose of this paper is to focus on the suitability of the multitrait-multimethod (MTMM) matrix approach for examining construct validity in human resource management (HRM) research. The authors also provide a number of suggestions on how to use MTMM more effectively in HRM research.

Design/methodology/approach
The authors start by presenting a basic introduction to MTMM approach. Next the authors briefly review the limitations of MTMM approach and suggested improvements. The authors elaborate on these limitations by providing HRM examples. To further illustrate these issues, the authors review employment interview research.

Findings
The construct validity analysis in HRM research suffers from three problematic assumptions of the classical MTMM approach: uncorrelated trait-method units, uncorrelated methods, and uncorrelated traits. The review of interview research shows that classical MTMM approach is by far the most popular approach given its relative simplicity and modest sample size requirements. This popularity stresses the significance of the review in highlighting these issues.

Originality/value
Several improvements to quantify the interpretations of MTMM analysis are available to researchers. This review closely examines how these limitations and proposed improvements influence HRM research, thereby making the methodological advances concerning the MTMM approach more accessible to HRM researchers and practitioners.