bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tetanus: Pathophysiology and Management
Authors: Ernst Michael E , Klepser Michael E , Fouts Michelle , Marangos Markos N 
Published: January 2017

OBJECTIVE: To review the epidemiology, pathophysiology, clinical manifestations, diagnosis, and management of tetanus and its complications. DATA SOURCES: MEDLINE and Iowa Drug Information Services databases were searched for literature pertaining to tetanus. Additional literature was obtained from the references of selected articles identified in the search. Information from all articles was considered for inclusion in the manuscript. STUDY SELECTION AND DATA EXTRACTION: Articles selected were those considered by the authors to assist in providing the reader an understanding of the epidemiology, pathophysiology, clinical manifestations, diagnosis, and management of tetanus. DATA SYNTHESIS: While the number of tetanus cases has decreased markedly since data reporting for the disease began in 1947, mortality among those who acquire the disease remains high. Elderly patients are particularly susceptible to tetanus and its complications. Prevention of tetanus focuses on primary immunization and scheduled boosters. Management of tetanus involves initial stabilization of the patient and protection of the airway, prevention of tetanospasmin absorption by administration of human tetanus immune globulin 3000–6000 IU, and eradication of Clostridium tetani with antimicrobial therapy (metronidazole 500 mg q8h). Supportive measures include the administration of neuromuscular blocking agents such as pancuronium in patients requiring artificial ventilation, as well as benzodiazepines (midazolam 5–15 mg/h) for sedation and muscle relaxation. Autonomic dysfunction should be managed with β-adrenergic blockers such as propranolol or labetalol. CONCLUSIONS: Despite the relative inffequency of tetanus cases, mortality among untreated patients remains significantly high. Clinicians should become knowledgeable in the pathophysiology, clinical manifestations, and management of this potentially fatal disease.
Congruity of the Subtalar Joint in Tongue Fracture of the Calcaneus: An Anatomical Study
Authors: Ebraheim Nabil A. , Sabry Fady F. , Haman Steve , Elgafy Hossein 
Published: January 2017

Study Design: An anatomic study. Objectives: To evaluate the effect of displacement of the fractured posterior facet in tongue fracture of the calcaneus on the congruity of the subtalar joint. Methods: Eleven feet were used in this study. Seven females and four males with age range from 59 to 78. The specimens were dissected from both the lateral and the medial aspects of the calcaneus to expose these surfaces. A primary fracture line was created first, then a secondary line was engineered to simulate tongue fracture. Displacement of the superio-lateral fragment was done with 5-mm increment. Radiography was performed and the graphs were scanned and studied on specific computer software to explore the effects of displacement on joint congruity. Results: The anterior end of the fragment of the tongue fracture, when displaced, not only is depressed but also rotated in the sagittal plane in a downward or planterward direction. The articular surface of the posterior facet of the calcaneus and the inferior facet of the talus are maintained in congruence with each other despite the varying degree of displacement and rotation. Conclusion: Congruity of the subtalar joint in tongue fractures is maintained despite different degrees of displacement. This study explains why the non-surgical treatment outcome is comparable to that of the operative treatment in tongue fractures of calcaneus. It also explains why tongue fractures have a good outcome with closed reduction.
Tarsal Coalition in Adults
Authors: Varner Kevin E. , Michelson James D. 
Published: January 2017

32 feet in 27 adults, seen at The Johns Hopkins Hospital Foot and Ankle Clinic from 1993-1998, with the diagnosis of tarsal coalition were retrospectively reviewed. There were 18 subtalar coalitions, 14 calcaneonavicular coalitions and 1 naviculocuneiform coalition. The average age was 40 years. Clinically, 22 feet had a neutral heel, 7 had a valgus heel with flattening of the longitudinal arch, 1 had a varus heel and 2 heels had an unknown position. Subtalar motion was decreased in 23 feet. Peroneal spasm was only seen in 2 patients. 11 feet were asymptomatic. Nonoperative treatment consisting of activity modification, nonsteroidal anti-inflammatory medications and casting was successful in the majority of patients. Subtalar fusion was performed in 4 feet and coalition resection in 1. The treatment of a symptomatic tarsal coalition in the adult is as in children but the clinical presentation may differ.
Primary Subtalar Arthrodesis of Calcaneal Fractures
Authors: Huefner T. , Thermann H. , Geerling J. , Pape H.C. , Pohlemann T. 
Published: January 2017

We evaluated retrospectively the long-term results of isolated calcaneal fractures treated with open reduction and internal fixation and a primary subtalar arthrodesis. From 1990 to 1997 258 patients were treated with a calcaneal fracture, for the current study six patients were included. Six different surgeons operated on the patients. The indication for the fusion was based on the comminution of the posterior facet according to the preoperative CT as well as the intraoperative evaluation of destruction of the cartilage. The restoration of length, axes and angles of the calcaneus was almost anatomical in all cases. Follow-up was done at a mean of 4.9 (2.5–7.5 years). Using the AOFAS score, the results were good or excellent in five patients. In one patient with a painful arthritis in the talonavicular joint and hyperesthesia of the sural nerve, the results were fair. All returned to their profession within 9 months and had no or only minor daily restrictions. The results are comparable with single surgeon series. We found open reconstruction of the calcaneus with primary fusion of the subtalar joint may be indicated in selected patients and, in these 6 patients led to good results.
The Adductor Hallucis Revisited
Authors: Owens Stephen , Thordarson David B. 
Published: January 2017

To evaluate anatomic variability in the insertion of the adductor hallucis into the lateral sesamoid and proximal phalanx of the great toe and to evaluate the extent of release of the adductor hallucis tendon performed through an incision in the dorsal first-web space, we recorded the angle of hallux valgus in 42 fresh-frozen specimens from human cadavers. An incision was made for a realignment of the soft tissues, dissecting down to the level of the intermetatarsal ligament. A loop of suture was placed around the identifiable adductor hallucis tendon through this incision along the lateral aspect of the lateral sesamoid. Then a plantar dissection removed all soft tissue to the level of the intermetatarsal ligament, adductor hallucis (transverse and oblique heads), lateral sesamoid, and lateral flexor hallucis brevis. The insertion of these muscles into the proximal phalanx was evaluated. Specifically, we looked for separate slips of the adductor tendon inserting into the base of the proximal phalanx or separate insertions of the adductor tendon and the tendon of the flexor hallucis brevis muscle. In 33 of the 42 specimens, the entire adductor hallucis tendon had been isolated by the loop of suture through the incision in the dorsal first web. In eight of the remaining nine specimens, a small slip of the tendon (comprising less than 25% of its substance) had not been included. No specimen was found to have a separate slip of the adductor tendon inserting into the base of the proximal phalanx. Instead, all specimens were found to have only a conjoined insertion of fibers of the adductor hallucis and of the flexor hallucis brevis from the lateral sesamoid into the base of the proximal phalanx. We did not identify a separate tendon-insertion into the proximal phalanx in any specimen. Therefore, great caution should be exercised in releasing an isolated insertion of the adductor tendon from the base of the proximal phalanx of the great toe since it may actually represent the conjoined insertion of the lateral flexor hallucis brevis tendon and the adductor tendon. We found that by simply releasing the adductor tendon from its insertion along the lateral aspect of the sesamoid, accomplished through an incision in the dorsal first web, that an adequate release was achieved in most specimens.
Surgical Treatment for Hallux Valgus with Painful Plantar Callosities
Authors: Okuda Ryuzo , Kinoshita Mitsuo , Morikawa Junichi , Jotoku Tsuyosi , Abe Muneaki 
Published: January 2017

We retrospectively reviewed the results of a distal soft-tissue procedure and proximal crescentic osteotomy of the first metatarsal combined with a proximal shortening osteotomy of the second and/or third metatarsal. This was in patients who had hallux valgus with painful plantar callosities. The review covered seven years of procedures (1989–1996) in 12 patients (14 feet) averaging 53 years of age. Average follow-up was 52 months. All patients had pain at the first metatarsophalangeal joint and had metatarsalgia preoperatively. At follow-up, 11 feet had no pain at the first metatarsophalangeal joint, and three had some improvement of pain. Ten feet had no metatarsalgia, two had improvement of metatarsalgia, and two feet had transfer lesions postoperatively and required reoperation. The angle of hallux valgus averaged 40 degrees preoperatively and 13 degrees postoperatively. The intermetatarsal angle averaged 18 degrees preoperatively and 6 degrees postoperatively. Mean decreases in length of the second and third metatarsal after surgery were 5.4 mm and 4.8 mm, respectively. Our results suggested that this combined procedure for hallux valgus with painful plantar callosities may be successful, in carefully selected patients.
The Effect of Posterior Tibial Tendon Dysfunction on Hindfoot Kinematics
Authors: Niki Hisateru , Ching Randal P. , Kiser Patti , Sangeorzan Bruce J. 
Published: January 2017

This biomechanical study investigated the functional role of the posterior tibial tendon (PTT) in acquired flatfoot mechanics. Acquired flatfoot deformity has been attributed to PTT dysfunction; however, the progression from acute dysfunction to end-stage deformity has not been fully demonstrated. Eight human cadaver lower leg and foot specimens were used in two phases of experimental testing. In Phase 1, intact (normal) specimens were loaded to simulate (a) heel strike, (b) stance, and (c) heel rise both with and without PTT function. Then, each specimen was subjected to a procedure designed to create a simulated flatfoot deformity. The resulting flattened feet were used in Phase 2 to examine the effect of restoring PTT function to a flatfoot model. During both phases of testing, the 3-D kinematic orientation of the hindfoot complex was recorded. Small but statistically significant changes in the angular orientation of the hindfoot complex were observed, during both Phase 1 and 2 testing, when comparing the effects of a functional and dysfunctional PTT. The greatest angular changes were recorded during heel rise. For the normal foot, the small changes observed in the orientation of the hindfoot complex following release of the PTT load suggest that the intact osteo-ligamentous structure of the hindfoot is initially able to maintain normal alignment following acute PTT dysfunction. Once the soft tissues have been weakened, as in our flatfoot model, the PTT had little effect in overcoming the soft tissue laxity to correct the position of the foot.
Bioabsorbable Versus Stainless Steel Screw Fixation of the Syndesmosis in Pronation-Lateral Rotation Ankle Fractures: A Prospective Randomized Trial
Authors: Thordarson David B. , Samuelson Michael , Shepherd Lane E. , Merkle Paul F. , Lee Jackson 
Published: January 2017

Thirty-two patients who had pronation-lateral rotation (PLR) fractures occurring four centimeters or more proximal to the ankle joint or lower if the talus was displaced greater than one centimeter laterally were enrolled in this study. Seventeen patients were randomized to fibular plate fixation with a 4.5 ml polylactic acid (PLA) bioabsorbable syndesmotic screw, and fifteen patients randomized to fibular plate fixation with a 4.5 mm stainless steel syndesmotic screw. All thirty-two patients had uncomplicated healing of their fibular fracture without loss of reduction. There was neither evidence of osteolysis nor sterile effusion in the patients who were treated with the PLA screw. There were no wound complications in either group. No difference in range of motion or subjective complaints was noted in either group. Use of the PLA syndesmotic screw at short-term follow-up was well tolerated and avoided the need for subsequent screw removal.
Anatomic Study of the Medial Neurovascular Structures in Relation to Calcaneal Osteotomy
Authors: Greene David L. , Thompson Michael C. , Gesink Dirk S. , Graves Stanley C. 
Published: January 2017

Medial displacement osteotomy of the calcaneous is commonly performed for stage II posterior tibial tendon insufficiency in an effort to improve the valgus deformity of the hindfoot. We performed an anatomic study examining the medial neurovascular anatomy and its relation to the osteotomy in an attempt to determine which structures may be at risk during the procedure. Calcaneal osteotomies were performed through a lateral approach on 22 fresh-frozen cadaver below-knee specimens. Dissection was then performed medially to identify the Medial Plantar Nerve (MPN), the Lateral Plantar Nerve (LPN), the Posterior Tibial Artery (PTA), and their respective branches. Measurements determined either 1) where the structure crossed the osteotomy or 2) if the structure did not cross, the closest perpendicular distance from the osteotomy and at which point along its length this occurred. Perpendicular distances were recorded in millimeters and position along the osteotomy as a percentage of the total length from the posterosuperior aspect. An average of four neurovascular structures crossed each osteotomy site (range 2 to 6), most of which were branches of the LPN or the PTA. The MPN did not cross in any of the specimens studied, the LPN crossed in one specimen, and the PTA crossed in two specimens. The MPN distributed no crossing branches. The calcaneal sensory branch of the LPN was identified and crossed in 86% of the cadavers at 19% (+/− 15%) along the osteotomy length. A more distal second branch of the LPN (Baxter's nerve) was identified and crossed in 95% of the specimens at 61% (+/ 20%) along the osteotomy length. A third crossing branch existed in one specimen. Each PTA distributed from zero to three branches which variably crossed the osteotomy at a point from 2% to 100% along its length. The PTA bifurcated in 77% of the specimens at 49% (+/− 9%) along the osteotomy length. A consistent finding in every specimen was the presence of two veins accompanying the PTA with one on either side. A number of medial neurovascular structures may be at risk when perfoming a calcaneal osteotomy through a lateral approach. A minimum of two structures crossed the osteotomy site at variable positions in this study, although most of these structures represented branches off of the LPN or the PTA, with the LPN and the PTA themselves crossing only infrequently. The authors recommend that the completion of the osteotomy through the medial calcaneal cortex be performed in a carefully controlled manner to reduce the risk of post-operative complications including pain, numbness, and hematoma formation.
Foot and Ankle Injuries in Motor Vehicle Accidents
Authors: Wilson Lynnford S. , Mizel Mark S. , Michelson James D. 
Published: January 2017

Background: We studied foot and ankle (F/A) injuries that occurred in motor vehicle accidents treated in a Level 1 trauma center. Methods: The records of F/A injuries of 2248 consecutive orthopedic patients were reviewed to find foot and ankle injuries. Results: Pilon fractures were common. Motor Vehicle Accident (MVA) occupants with F/A injuries had a higher injury Severity Score than those without (17.9 vs. 11.6, p <. 001). MVA F/A injury risk was higher without restraint [relative risk ratio (rrr) 1.68, p <. 0032] than with restraint except for air bagged drivers who were similar to unrestrained drivers (rrr 1.18, p > .05, NS). Conclusion: Patients with F/A injuries may have serious associated injuries. Air bags may not protect feet.
An Evaluation of the Use of Retrospectively Acquired Preoperative AOFAS Clinical Rating Scores to Assess Surgical Outcome after Elective Foot and Ankle Surgery
Authors: Toolan Brian C. , Quinones Vonda J. Wright , Cunningham Benjamin J. , Brage Michael E. 
Published: January 2017

The use of retrospectively acquired preoperative AOFAS rating scores in clinical research to assess the outcomes of elective foot and ankle surgery has not been validated. The data obtained utilizing this methodology may misrepresent the results and lead to spurious conclusions. This investigation compared preoperative AOFAS Ankle-Hindfoot scores obtained before and after surgery from patients who had undergone elective surgery to determine if retrospectively acquired scores match those collected prospectively. Only two out of 47 patients (4%) recalled identical AOFAS scores. The mean difference between the preoperative scores (preoperative score obtained after surgery minus preoperative score obtained before surgery) was −5.3 points. Fifteen patients (32%) had preoperative scores that differed by 20 points or more. Kappa statistics found little agreement among the five elements that comprised the two preoperative scores when responses obtained before and after surgery were compared to one another. The results suggest that preoperative clinical rating scores obtained after elective surgery are a poor predictor of the patient's preoperative condition and that studies which employ retrospectively acquired preoperative AOFAS clinical rating scores may overestimate the benefit of surgery.
Shockwave Therapy for Chronic Proximal Plantar Fasciitis: A Meta-Analysis
Authors: Ogden John A. , Alvarez Richard G. , Marlow Marie 
Published: January 2017

Purpose: Utilizing meta-analysis, the authors have reviewed the available literature to assess the biologic and therapeutic effects of shockwaves on patients with chronic plantar fasciitis and the credibility of these published studies. Methods: Meta-analysis is a systematic method for statistical analysis that combines data from various independent studies, allowing the assessment of potential benefits of various treatments when conclusions based on individual studies may be difficult to evaluate. We hypothesized that extracorporeal shockwave therapy provided a reasonable nonoperative therapeutic alternative to surgical intervention in the treatment of chronic proximal plantar fasciitis. Results: Eight of 20 published studies fulfilled our type A to C criteria for acceptable studies of sufficient duration (one year or more after treatment). These eight studies involved 840 patients, with success rates of as much as 88%. The other 12 studies had methodological variables or lack of appropriate follow-up data that would limit their validity, although the success rates were comparable to the A to C studies. Conclusions: This meta-analysis shows that the directed application of shockwaves to the enthesis of the plantar fascia at the inferior calcaneus is a safe and effective nonsurgical method for treating chronic, recalcitrant heel pain syndrome that has been refractory to other commonly used nonoperative therapies. The results suggest that this therapeutic procedure should be considered before any surgical intervention, and may be preferable prior to cortisone injection, which has a recognized risk of rupture of the plantar fascia and a frequent recurrence of symptoms.
Surgeon Training and Complications in Total Ankle Arthroplasty
Authors: Saltzman Charles L. , Amendola Annunziato , Anderson Robert , Coetzee J. Chris , Gall Randall J. , Haddad Steven L. , Herbst Steven , Lian George , Sanders Roy W. , Scioli Mark , Younger Alistair S. 
Published: January 2017

Background: This study assessed the problems with initial use of ankle arthroplasty by surgeons who were trained by observing the surgeon/inventor (group I), who have completed a structured, hands-on surgical training course (group II), or who were trained during a 1-year foot and ankle fellowship (group III). Materials and Methods: The perioperative records of the first 10 cases of nine surgeons were reviewed. We evaluated the 6-month-postoperative standing mortise and lateral radiographs for evidence of syndesmosis union and accuracy of tibial component implantation. Three surgeons were each in group I, group II, and group III. Average patient age at time of surgery was similar. Ankle arthritis was classified as rheumatoid arthritis (RA) or osteoarthritis (OA) as follows: group I (7 RA, 23 OA), group II (7 RA, 23 OA), and group III (3 RA, 27 OA). Results: In group I, there were nine intraoperative complications, four postoperative wound dehiscences, and three postoperative deep infections. Radiographic evaluation of the 26 cases with adequate postoperative roentgenograms revealed that 10/26 (38%) had a delayed union of the syndesmosis. In group II, there were six intraoperative complications and two postoperative wound problems: an early anterior wound problem and a delayed lateral wound breakdown. Radiographic evaluation of the 26 cases with adequate postoperative roentgenograms revealed that 13/26 (50%) had a delayed union of the syndesmosis. In group III, there were four intraoperative complications and four postoperative wound problems – all healed with local supportive care with one requiring lateral hardware removal. Radiographic evaluation of the 26 cases with adequate postoperative roentgenograms revealed that 5/30 (17%) had a delayed union of the syndesmosis. The initial series from these three groups are statistically indistinguishable with respect to rates of complications, revisions, or malalignment. Conclusion: No identified training method had a statistically demonstrable positive impact on preparing surgeons for performing total ankle replacement. Some of these findings are likely generic for total ankle replacements and not restricted to any class or design of implant. Surgeon initial use of total ankle replacement needs to be done with caution and serious consideration.