bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the dark side of high-performance work systems: growing employee employability at the cost of retention?
Authors: Haar Jarrod 
Published: September 2024

PurposeWhile high-performance work systems (HPWS) are widely viewed as beneficial, some suggest they may have a dark side and be simultaneously detrimental. This is tested toward turnover intentions (reduced by HPWS) in the context of perceived employability because HPWS are expected to enhance employability, which positively influences turnover intentions.Design/methodology/approachSurvey data using two New Zealand employee studies were conducted (n = 525, n = 306). Data were analyzed for mediation (Study 1) and moderated mediation (Study 2) using the PROCESS macro.FindingsBoth studies show HPWS are negatively related to turnover intentions and positively to perceived employability, which also positively influences turnover intentions. This provides support for dark side effects. Study two extends the model by including career planning and tests a moderated mediation model, showing the indirect effects of HPWS being positive toward turnover intentions in the context of perceived employability at all levels of career planning. This indirect effect weakens as career planning strengthens.Originality/valueHighlights that HPWS appear to have a dark side by positively shaping employability and ultimately turnover intentions when career planning is included as a boundary condition.
Harvesting success: Metaverse adoption in agriculture sector as a sustainable business strategy
Authors: Sarkar Bishal Dey , Shardeo Vipulesh , Mir Umar Bashir , Negi Himanshi 
Published: September 2024

PurposeThe disconnect between producers and consumers is a fundamental issue causing irregularities, inefficiencies and leakages in the agricultural sector, leading to detrimental impacts on all stakeholders, particularly farmers. Despite the potential benefits of Metaverse technology, including enhanced virtual representations of physical reality and more efficient and sustainable crop and livestock management, research on its impact in agriculture remains scarce. This study aims to address this gap by identifying the critical success factors (CSFs) for adopting Metaverse technology in agriculture, thereby paving the way for further exploration and implementation of innovative technologies in the agricultural sector.Design/methodology/approachThe research employed integrated methodology to identify and prioritise critical success criteria for Metaverse adoption in the agricultural sector. By adopting a mixed-method technique, the study identified a total of 15 CSFs through a literature survey and expert consultation, focusing on agricultural and technological professionals and categorising them into three categories, namely “Technological”, “User Experience” and “Intrinsic” using Kappa statistics. Further, the study uses grey systems theory and the Ordinal Priority Approach to prioritise the CSFs based on their weights.FindingsThe study identifies 15 CSFs essential for adopting Metaverse technology in the agricultural sector. These factors are categorised into Technological, User Experience-related and Intrinsic. The findings reveal that the most important CSFs for Metaverse adoption include market accessibility, monetisation support and integration with existing systems and processes.Practical implicationsIdentifying CSFs is essential for successful implementation as a business strategy, and it requires a collaborative effort from all stakeholders in the agriculture sector. The study identifies and prioritises CSFs for Metaverse adoption in the agricultural sector. Therefore, this study would be helpful to practitioners in Metaverse adoption decision-making through a prioritised list of CSFs in the agricultural sector.Originality/valueThe study contributes to the theory by integrating two established theories to identify critical factors for sustainable agriculture through Metaverse adoption. It enriches existing literature with empirical evidence specific to agriculture, particularly in emerging economies and reveals three key factor categories: technological, user experience-related and intrinsic. These categories provide a foundational lens for exploring the impact, relevance and integration of emerging technologies in the agricultural sector. The findings of this research can help policymakers, farmers and technology providers encourage adopting Metaverse technology in agriculture, ultimately contributing to the development of environment-friendly agriculture practices.
Earnings, Productivity and Housing Expenditure: Who Retains the Wage‐Related Agglomeration Effect?
Authors: Nygaard Christian A. 
Published: September 2024

ABSTRACTProductivity gains enable real wage growth and improved standards of living. But whose income actually benefits from productivity gains when highly productivity urban locations in Australia, and other advanced economies, also are associated with worsening housing affordability and inequality? This paper answers this question by empirically testing whether agglomeration effects vary across the wage distribution in Australia? And, how much of any agglomeration effect is retained by individuals across the wage distribution? Unconditional quantile regressions are employed to analyse changes in agglomeration effects across the before‐ and after‐housing cost wage distribution. Information on individual earnings, housing costs and place of employment is sourced from the Household, Income and Labour Dynamics in Australia (HILDA). The paper utilises four pre‐COVID waves of HILDA (2017–2020) as details on place of employment was first introduced in 2017. Agglomeration indices are constructed from Australian Bureau of Statistics census data using 17 industry (ANZSIC) classifications (2016, 2021). The results show that the before‐housing cost wages of higher‐wage earners typically benefit twice as much as those of lower‐wage earners. However, after adjusting for housing expenditure (mortgage payments and rents) the after‐housing costs wage benefit for the lowest two wage earning deciles disappear and is transferred to owners of real estate. Higher wage earners retain approximately 50%–60% of the agglomeration benefit. It is thus higher wage earner, and owners of land and property, who typically benefit from agglomeration related productivity—often at the expense of lower‐wage earners.
Russia's Trade With G7 Countries and Asymmetric J‐Curve Effect
Authors: Bahmani‐Oskooee Mohsen , Aftab Muhammad , Karamelikli Huseyin 
Published: September 2024

ABSTRACTThis study investigates the relationship between exchange rates and trade balance, specifically focusing on Russia's trade dynamics with the Group of Seven (G7) countries. Employing a multifaceted approach, we scrutinize the asymmetric responses evident in the trade balance concerning fluctuations in exchange rates. Our investigation, rooted in linear analysis, initially reveals that rubble depreciation predominantly impacts the Russian trade balance adversely in the short term, albeit demonstrating a positive influence on trade balance in select instances over the long run—an observation aligned with the established J‐curve phenomenon. However, as we transition to nonlinear analysis, our findings yield stronger substantiation for the J‐curve hypothesis. Notably, our research underscores the asymmetric nature of exchange rate changes' effects on trade balance. Moreover, through nonlinear modeling techniques, we observe a pronounced enhancement in the convergence toward establishing a long‐term relationship between these variables. This emphasizes the significance of nonlinear approaches in comprehending the complexities inherent in exchange rate‐trade balance dynamics of Russian trade with G7.
A review of conditions influencing fate of Shiga toxin‐producing Escherichia coli O157:H7 in leafy greens
Authors: Owade Joshua Ombaka , Bergholz Teresa M. , Mitchell Jade 
Published: September 2024

AbstractThe accuracy of predictive microbial models used in quantitative microbial risk assessment (QMRA) relies on the relevancy of conditions influencing growth or inactivation. The continued use of log‐linear models in studies remains widespread, despite evidence that they fail to accurately account for biphasic kinetics or include parameters to account for the effect of environmental conditions within the model equation. Although many experimental studies detail conditions of interest, studies that do not do so lead to uncertainty in QMRA modeling because the applicability of the predictive microbial models to the conditions in the risk scenarios is questionable or must be extrapolated. The current study systematically reviewed 65 articles that provided quantitative data and documented the conditions influencing the inactivation or growth of Shiga toxin‐producing Escherichia coli (STEC) O157:H7 in leafy greens. The conditions were identified and categorized as environmental, biological, chemical, and/or processing. Our study found that temperature (n = 37 studies) and sanitizing and washing procedures (n = 12 studies) were the most studied conditions in the farm‐to‐table continuum of leafy greens. In addition, relative humidity was also established to affect growth and inactivation in more than one stage in the continuum. This study proposes the evaluation of the interactive effects of multiple conditions in processing and storage stages from controlled experiments as they relate to the fate of STEC O157:H7 in leafy greens for future quantitative analysis.
The potential of orally exposed risk factors and constituents aggravating food allergy: Possible mechanism and target cells
Authors: Xu Xiaoqian , Yuan Jin , Zhu Mengting , Gao Jinyan , Meng Xuanyi , Wu Yong , Li Xin , Tong Ping , Chen Hongbing 
Published: September 2024

AbstractFood allergy is a significant concern for the health of humans worldwide. In addition to dietary exposure of food allergens, genetic and environmental factors also play an important role in the development of food allergy. However, only the tip of the iceberg of risk factors in food allergy has been identified. The importance of food allergy caused by orally exposed risk factors and constituents, including veterinary drugs, pesticides, processed foods/derivatives, nanoparticles, microplastics, pathogens, toxins, food additives, dietary intake of salt/sugar/total fat, vitamin D, and therapeutic drugs, are highlighted and discussed in this review. Moreover, the epithelial barrier hypothesis, which is closely associated with the occurrence of food allergy, is also introduced. Additionally, several orally exposed risk factors and constituents that have been reported to disrupt the epithelial barrier are elucidated. Finally, the possible mechanisms and key immune cells of orally exposed risk factors and constituents in aggravating food allergy are overviewed. Further work should be conducted to define the specific mechanism by which these risk factors and constituents are driving food allergy, which will be of central importance to the targeted therapy of food allergy.
Serum calciprotein particle‐to‐phosphate ratio as a predictor of cardiovascular events in incident hemodialysis patients
Authors: Akiyama Tomoki , Iwazu Yoshitaka , Usui Joichi , Ebihara Itaru , Ishizu Takashi , Kobayashi Masaki , Maeda Yoshitaka , Kobayashi Hiroaki , Yamagata Kunihiro , Kuro‐o Makoto ,   The Study Group of the Ibaraki Dialysis Initiation Cohort Study
Published: September 2024

AbstractIntroductionRecent studies have identified increased blood calciprotein particle (CPP) levels as risk factors for vascular calcification and cardiovascular events in patients undergoing maintenance hemodialysis. Although positively correlated with serum phosphate levels, serum CPP levels vary considerably among patients with similar serum phosphate levels. We investigated the capacity of the ratio of serum CPP levels to serum phosphate levels (CPP/Pi ratio) to predict cardiovascular events in incident hemodialysis patients compared to the serum calcification propensity test (T50).Methods and ResultsThe association between the CPP/Pi ratio and major adverse cardiac and cerebrovascular events (MACCE) was investigated in 174 incident hemodialysis patients. Multivariate analysis revealed that the CPP/Pi ratio was independently associated with MACCE [hazard ratio 1.60, 95% confidence interval (1.15–2.23), p = 0.006] but serum T50 levels were not.ConclusionsThe CPP/Pi ratio is a useful, novel biomarker for predicting the risk of cardiovascular events in patients undergoing incident hemodialysis.
Public perceptions of dietetics services in Australia and New Zealand
Authors: Forsyth Adrienne , Beck Eleanor , Kruger Rozanne , Pelly Fiona , Wall Clare , Boak Rachel , Allman‐Farinelli Margaret 
Published: September 2024

AbstractAimThe aim of this study was to examine expectations, perceptions and attitudes about dietetics services among the Australian and New Zealand public, to provide insights for building a future dietetics workforce that will meet consumer needs.MethodsA cross‐sectional, anonymous, online survey was employed to gain perspectives of a representative sample of Australian and New Zealand adults. Questions were purposely designed to collect views regarding sources of dietary information, expectations of dietetics service providers and factors influencing choice of dietetics service provider. Data were analysed descriptively and using Pearson's chi‐square test to assess relationships between categorical variables. Free‐text responses were analysed using content analysis.ResultsOf 2601 respondents, approximately one third (32%) had seen a dietitian. Doctors were the most trusted sources of dietary information (87%), particularly with participants over 60 years (χ(1) = 44.168, V = 0.130, p < 0.001). Cost was the most frequently reported factor influencing choice of dietetics services (56%), with 88% of respondents interested in accessing a dietitian, preferably in‐person (64%), if they could do so for no cost. Participants anticipated that dietitians would offer services like meal plans (59%) and nutritional analysis (48%) as well as weight and other body measurements (56%). Some expectations such as blood tests (54%) were outside the usual scope of dietetic practice.ConclusionThe results of this study have implications for practising dietitians, dietetics educators, and funders of dietetics services. Cost as a barrier suggests that advocacy to government for funding type, duration and number of visits to dietitians is still required.
Relationship between sleep bruxism and obstructive sleep apnoea: A population‐based survey
Authors: Pollis M , Lobbezoo F , Colonna A , Manfredini D 
Published: September 2024

AbstractObjectiveSleep bruxism (SB) and obstructive sleep apnoea (OSA) seem to be mutually associated. This study investigates the relationship between current SB and OSA‐related symptoms and the difference in OSA‐related symptoms between groups based on a history of SB.MethodsAn online survey was drafted to report the presence of SB and OSA in sample of 243 individuals (M = 129;F = 114;mean(SD)age = 42.4 ± 14.4 years). The Subject‐Based Assessment strategy recommended in the ‘Standardized Tool for the Assessment of Bruxism’ (STAB) was adopted to assess SB. To evaluate OSA‐related symptoms, Epworth Sleepiness Scale (ESS) and STOP‐BANG questionnaires were adopted. Correlations between current SB and OSA‐related symptoms were evaluated by Spearman test. ESS and STOP‐BANG scores were compared by Mann–Whitney U test in individuals with and a without positive SB history.ResultsCurrent SB and SB history were reported by 45.7% and 39.1% of the sample, respectively. 73.7%, 21% and 5.3% of the responders showed a low, intermediate and high risk of OSA, respectively. Neither significant correlations between current SB and OSA nor significant differences between SB groups emerged.ConclusionsThis study did neither find any significant correlation between self‐report of current SB and OSA nor significant differences in ESS and STOP‐BANG scores between groups based on SB history.
Influence of age and co‐medication on dolutegravir glucuronidation in paediatric patients
Authors: Jacobs Tom G. , Waalewijn Hylke , Houlden Lily , Bollen Pauline D. J. , Nanduudu Annet , Nambi Esether , Cassim Haseena , Lugemwa Abbas , Makumbi Shafic , Monkiewicz Lara N. , Shakeshaft Clare , Bamford Alasdair , Archary Moherndran , Musuro Godfrey , Chidziva Ennie , Mujuru Hilda A. , Bwakura‐Dangarembizi Mutsa , Chabala Chishala , Turkova Anna , Gibb Di M. , Cotton Mark F. , Aarnoutse Rob , Burger David M. , Colbers Angela 
Published: September 2024

AbstractDolutegravir (DTG) is primarily metabolized by uridine diphosphate glucuronosyltransferases, forming the pharmacologically inactive DTG glucuronide (DTG‐gluc). We described the dolutegravir metabolic ratio (DTG‐MR; DTG‐gluc AUC0–24h divided by DTG AUC0–24h) in 85 children with HIV aged 3 months to 18 years receiving DTG in the CHAPAS‐4 (ISRCTN22964075) and ODYSSEY (NCT02259127) trials. Additionally, we assessed the influence of age, body weight, nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) backbone, rifampicin use and kidney function on DTG‐MR. The overall geometric mean (CV%) DTG‐MR was 0.054 (52%). Rifampicin use was the only significant factor associated with DTG‐MR (P < .001) in multiple linear regression. DTG‐MR geometric mean ratio was 1.81 (95% CI: 1.57–2.08) for children while on vs. off rifampicin. This study showed that overall DTG‐MR in children was similar to adults, unaffected by age or NRTI backbone, and increased with rifampicin co‐administration. These findings support future paediatric pharmacokinetic modelling and extrapolation from adult data.
Evaluation of coverage, generalisability and validity of the U‐CAN lymphoma biobank in Sweden: A comparison with nationwide registers
Authors: Forsgren Elin , Ekberg Sara , Smedby Karin E. , Nylund Patrick , Sjöblom Tobias , Flogegård Max , Sjöström Sara , Hultdin Magnus , Hallén Karin , Hellström Mats , Molin Daniel , Enblad Gunilla , Glimelius Ingrid 
Published: September 2024

SummaryValidation of biobanks and large cancer cohorts is essential in ensuring high‐quality research results. We examined the coverage, generalisability and validity of the lymphoma collection of the Uppsala‐Umeå Comprehensive Cancer Consortium (U‐CAN) biobank in Sweden, one of the largest cancer biobanks in Europe. Up until 2022, 889 lymphoma patients in U‐CAN Uppsala had available samples, and 329 in U‐CAN Umeå. Patients diagnosed in the U‐CAN Uppsala area 2011–2021 (n = 843) were linked to the nationwide Swedish Lymphoma Register, and a subset diagnosed before 2019 (n = 727) to population‐based registers. The coverage was 39% of all lymphoma patients between 2011 and 2019 diagnosed in the U‐CAN Uppsala area, with a pandemic decline to 10% during 2020–2021. The patients included had superior overall survival (hazard ratio = 0.70 [95% confidence interval, CI: 0.60–0.82]) than all lymphoma patients in Sweden. They had better performance status, were younger (odds ratio [OR] = 0.21 [95% CI: 0.13–0.34]) and had less comorbidities (OR = 0.66 [95% CI: 0.56–0.78]). However, cause‐specific survival and stage distribution were similar. The questionnaire data captured less comorbidities compared to the national registers. Evaluations of biobanks are important, as even population‐based biobanks such as U‐CAN select younger patients with higher socioeconomical status and better performance status. However, the similar cause‐specific survival as in the registries suggests U‐CANs usefulness for prognostic biomarker studies.
Friendlessness and loneliness: Cultural frames for making sense of disconnection
Authors: Eramian Laura , Mallory Peter , Herbert Morgan 
Published: September 2024

AbstractThis article is based on 21 interviews in an Atlantic Canadian city with people who identified as having few or no friends. With all the talk of a modern loneliness epidemic, we might easily assume friendless people are lonely, yet here we take an interpretive approach to analyze how they alternately claim to experience and not experience loneliness. We argue that claims to loneliness or its absence are never merely personal stories or problems of individual health or wellbeing, but are shaped by larger cultural resources and meanings. We found that friendless people both lament and celebrate their disconnection, a duality that we theorize through competing views of the modern self as both autonomous/self‐reliant and fundamentally in need of connection and community. We show how our interviewees struggle to find meaning in their disconnection and self‐respect in a society where being friendless is open to stigma or pity.
Pharmacokinetics of olverembatinib (HQP1351) in the presence of a strong CYP3A4 inhibitor (itraconazole) or inducer (rifampin) in healthy volunteers
Authors: Wang Hengbang , Yang Yun , Chen Zi , Fu Lei , Yu Min , Jiang Lixin , Wang Cunlin , Men Lichuang , Minto Ilisse , Yang Dajun , Zhai Yifan 
Published: September 2024

AbstractOlverembatinib (HQP1351) is a BCR‐ABL1 tyrosine kinase inhibitor with promising clinical activity. It is approved in China for the treatment of patients with chronic myeloid leukemia harboring drug‐resistant mutations, such as T315I. In vitro studies suggested that metabolism of olverembatinib is primarily mediated by cytochrome P450 (CYP3A4). The effects of CYP3A4 inhibition and induction on the pharmacokinetics of olverembatinib were evaluated in an open‐label, 2‐part, fixed‐sequence study in healthy volunteers. In Part 1 of this study, 16 participants received a single oral dose of olverembatinib (20 mg) and the oral CYP3A4 inhibitor itraconazole (200 mg). In Part 2, 16 participants received a single oral dose of olverembatinib (40 mg) and the oral CYP3A4 inducer rifampin (600 mg). To measure pharmacokinetic parameters, serial blood samples were collected after administration of olverembatinib alone and combined with itraconazole or rifampin. Coadministration of olverembatinib with itraconazole increased the peak plasma concentration of olverembatinib, its area under the time‐concentration curve (AUC)0‐last, and AUC0‐inf by 75.63%, 147.06%, and 158.66%, respectively. Coadministration with rifampin decreased these same variables by 61.27%, 74.21%, and 75.19%, respectively. These results confirm that olverembatinib is primarily metabolized by CYP3A4 in humans, suggesting that caution should be exercised with concurrent use of olverembatinib and strong CYP3A4 inhibitors or inducers.