bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regional Integration through Law and International Courts – the Interplay betweenDe JureandDe FactoSupranationality in Central America and the Caribbean
Authors: CASERTA SALVATORE 
Published: June 2017

AbstractThe article proposes an innovative theoretical framework outlining preconditions for Regional International Courts (RICs) to act as engines of supranationality in different institutional and socio-political contexts. In so doing, the article nuances the theoretical approaches to supranationality and supranational adjudication. The article focuses on the Central American Court of Justice (CACJ) and the Caribbean Court of Justice (CCJ). Both courts have been branded institutional copies of the Court of Justice of the European Union (CJEU); they have even borrowed key jurisprudential principles from the Luxembourg Court with the goal of expanding the reach of Central American and Caribbean Community Laws. Yet, both the CACJ and the CCJ have thus far failed to foster supranationality in their respective systems. This is because the conditions allowing RICs to become engines of integration lie, for the most part, beyond the direct control of the judges, most notably, with other institutional, political, and societal actors, such as national judges, regional organs, legal and political elites, as well as academics. The article thus suggests that RICs can become engines of supranationality only to the extent to which they are supported by a set of institutional, political, and societal pre-conditions allowing for the concrete enforcement of the rulings of the RIC at the regional and national levels.
Thirty years of human infections caused by Yersinia enterocolitica in northern Spain: 1985–2014
Authors: MARIMON J. M. , FIGUEROA R. , IDIGORAS P. , GOMARIZ M. , ALKORTA M. , CILLA G. , PÉREZ-TRALLERO E. 
Published: June 2017

SUMMARYYersinia enterocolitica infection is a zoonosis with worldwide distribution, gastroenteritis being by far the most common clinical manifestation of human infection. In Gipuzkoa, northern Spain, human Y. enterocolitica infections increased from the mid-1980s to the beginning of the 21st century (from 7·9 to 23·2 annual episodes per 100 000 population) to decrease to 7·2 annual episodes per 100 000 population in the last years of the study. The hospital admission rate due to yersiniosis during the last 15 years of the study was 7·3%. More than 99% of isolates were serotype O:3. Infection affected mainly children under 5 years of age (average rate: 140 episodes per 100 000 population). The incidence in adults was low but hospitalisation increased with age, exceeding 50% in people over 64 years old.
Pertussis diagnosis in Belgium: results of the National Reference Centre for Bordetella anno 2015
Authors: MARTINI H. , RODEGHIERO C. , VAN DEN POEL C. , VINCENT M. , PIERARD D. , HUYGEN K. 
Published: June 2017

SUMMARYIn 2015, the Belgian National Reference Centre for Bordetella analyzed 4110 respiratory samples by qPCR and 4877 serum samples by serology. Whereas about 50% of respiratory samples were from infants and children below the age of five, serum samples were distributed among all age categories. A total of 394 (9·6%) cases was diagnosed as positive for Bordetella pertussis by qPCR and 844 (17·3%) cases were diagnosed as acute infection by serology (anti-pertussis toxin (PT) IgG > 125 IU/ml). Another 1042 (21·4%) sera had anti-PT IgG between 55 and 125 IU/ml reflecting a vaccination or pertussis infection during the last 1–2 years. Seventy per cent of the pertussis cases diagnosed by qPRC were in infants and children younger than 14 years old, whereas the highest number of sera with anti-PT levels >125 IU/ml was in the age group of 10–14 years old. Based on the limited data of the last vaccination (reported for only 15% of the samples), recent booster vaccination in the teenager group may have contributed only minimally to these elevated anti-PT levels. The highest number of sera with anti-PT titers between 55 and 125 IU/ml was found in the age category 50–59 years old. It is clear that pertussis continues to be a problem in Belgium and that other vaccination strategies (maternal vaccination, cocoon vaccination) and ultimately better vaccines will be needed to control this highly infectious respiratory disease.
The commercial NLP landscape in 2017
Authors: DALE ROBERT 
Published: June 2017

AbstractThe commercialisation of natural language processing began over 35 years ago, but it’s only in the last year or two that it’s become substantially more visible, largely because of the intense popular interest in artificial intelligence. So what’s the state of commercial NLP today? We survey the main industry categories of relevance, and offer comment on where the action is today.
Statistically Derived Subtypes and Associations with Cerebrospinal Fluid and Genetic Biomarkers in Mild Cognitive Impairment: A Latent Profile Analysis
Authors: Eppig Joel S. , Edmonds Emily C. , Campbell Laura , Sanderson-Cimino Mark , Delano-Wood Lisa , Bondi Mark W. ,   for the Alzheimer’s Disease Neuroimaging Initiative
Published: June 2017

AbstractObjectives: Research demonstrates heterogeneous neuropsychological profiles among individuals with mild cognitive impairment (MCI). However, few studies have included visuoconstructional ability or used latent mixture modeling to statistically identify MCI subtypes. Therefore, we examined whether unique neuropsychological MCI profiles could be ascertained using latent profile analysis (LPA), and subsequently investigated cerebrospinal fluid (CSF) biomarkers, genotype, and longitudinal clinical outcomes between the empirically derived classes. Methods: A total of 806 participants diagnosed by means of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) MCI criteria received a comprehensive neuropsychological battery assessing visuoconstructional ability, language, attention/executive function, and episodic memory. Test scores were adjusted for demographic characteristics using standardized regression coefficients based on “robust” normal control performance (n=260). Calculated Z-scores were subsequently used in the LPA, and CSF-derived biomarkers, genotype, and longitudinal clinical outcome were evaluated between the LPA-derived MCI classes. Results: Statistical fit indices suggested a 3-class model was the optimal LPA solution. The three-class LPA consisted of a mixed impairment MCI class (n=106), an amnestic MCI class (n=455), and an LPA-derived normal class (n=245). Additionally, the amnestic and mixed classes were more likely to be apolipoprotein e4+ and have worse Alzheimer’s disease CSF biomarkers than LPA-derived normal subjects. Conclusions: Our study supports significant heterogeneity in MCI neuropsychological profiles using LPA and extends prior work (Edmonds et al., 2015) by demonstrating a lower rate of progression in the approximately one-third of ADNI MCI individuals who may represent “false-positive” diagnoses. Our results underscore the importance of using sensitive, actuarial methods for diagnosing MCI, as current diagnostic methods may be over-inclusive. (JINS, 2017, 23, 564–576)
25-Hydroxyvitamin D supplementation and health-service utilization for upper respiratory tract infection in young children
Authors: Omand Jessica A , To Teresa , O’Connor Deborah L , Parkin Patricia C , Birken Catherine S , Thorpe Kevin E , Maguire Jonathon L 
Published: June 2017

AbstractObjectiveUpper respiratory tract infections (URTI) are the most common and costly condition of childhood. Low vitamin D levels have been hypothesized as a risk factor for URTI. The primary objective was to determine if serum vitamin D levels were associated with health-service utilization (HSU) for URTI including hospital admission, emergency department visits and outpatient sick visits. The secondary objectives were to determine whether oral vitamin D supplementation in pregnancy or childhood was associated with HSU for URTI.DesignCohort study. HSU was determined by linking each child’s provincial health insurance number to health administrative databases. Multivariable quasi Poisson regression was used to evaluate the association between 25-hydroxyvitamin D, vitamin D supplementation and HSU for URTI.SettingToronto, Canada.SubjectsChildren participating in the TARGet Kids! network between 2008 and 2013.ResultsHealthy children aged 0–5 years (n 4962) were included; 52 % were male and mean 25-hydroxyvitamin D was 84 nmol/l (range 11–355 nmol/l). There were 105 (2 %), 721 (15 %) and 3218 (65 %) children with at least one hospital admission, emergency department visit or outpatient sick visit for URTI, respectively. There were no statistically significant associations between 25-hydroxyvitamin D or vitamin D supplementation and HSU for URTI.ConclusionsA clinically meaningful association between vitamin D (continuously and dichotomized at <50 and <75 nmol/l) and HSU for URTI was not identified. While vitamin D may have other benefits for health, reducing HSU for URTI does not appear to be one of them.
Drivers of dietary behaviours in women living in urban Africa: a systematic mapping review
Authors: Gissing Stefanie C , Pradeilles Rebecca , Osei-Kwasi Hibbah A , Cohen Emmanuel , Holdsworth Michelle 
Published: June 2017

AbstractObjectiveTo (i) systematically review the literature to determine the factors influencing diet and dietary behaviour in women living in urban Africa; (ii) present these in a visual map; and (iii) utilize this to identify potentially important areas for future research.DesignSystematic mapping review. The review protocol was registered at PROSPERO (http://www.crd.york.ac.uk/PROSPERO/; registration number CRD42015017749). Six databases were systematically searched, followed by reference and citation searching. Eligibility criteria included women aged 18–70 years living in urban Africa, any design/methodology, exploring any driver, using any measure of dietary behaviour. Quality appraisal occurred parallel with data extraction. Twelve predominantly cross-sectional quantitative studies were included; reported in seventeen publications. Determinants were synthesized narratively and compiled into a map adapted from an existing ecological model based on research in high-income countries.SettingUrban Africa.SubjectsAfrican women aged 18–70 years.ResultsDeterminants significantly associated with unhealthy dietary behaviour ranged from the individual to macro level, comprising negative body image perception, perceptions of insufficient food quantity and poorer quality, poorer food knowledge, skipping meals, snacking less, higher alcohol consumption, unhealthy overall lifestyle, older age, higher socio-economic status, having an education, lower household food expenditure, frequent eating outside the home and media influence. Marital status and strong cultural and religious beliefs were also identified as possible determinants.ConclusionsFew studies have investigated drivers of dietary behaviours in urban African settings. Predominantly individual-level factors were reported. Gaps in the literature identified a need for research into the neglected areas: social, physical and macro-level drivers of food choice.
Eating frequency and weight and body composition: a systematic review of observational studies
Authors: Canuto Raquel , da Silva Garcez Anderson , Kac Gilberto , de Lira Pedro Israel Cabral , Olinto Maria Teresa Anselmo 
Published: June 2017

AbstractObjectiveThe present review aimed to examine the association of eating frequency with body weight or body composition in adults of both sexes.DesignPubMed, EMBASE and Scopus databases were searched. PRISMA and MOOSE protocols were followed. Observational studies published up to August 2016 were included. The methodological quality of the studies was assessed with the Downs and Black checklist.SettingA systematic review of the literature.SubjectsAdults (n 136 052); the majority of studies were developed in the USA and Europe.ResultsThirty-one articles were included in the review: two prospective and twenty-nine cross-sectional studies. Thirteen per cent of the studies received quality scores above 80 %. The assessment of eating frequency and body composition or body weight varied widely across the studies. Potential confounders were included in 73 % of the studies. Fourteen studies reported an inverse association between eating frequency and body weight or body composition, and seven studies found a positive association. The majority of studies applied multiple analyses adjusted for potential confounders, such as sex, age, education, income, smoking, physical activity and alcohol intake. Six studies took into account under-reporting of eating frequency and/or energy intake in the analysis, and one investigated the mediation effect of energy intake.ConclusionsThere is not sufficient evidence confirming the association between eating frequency and body weight or body composition when misreporting bias is taken into account. However, in men, a potential protective effect of high eating frequency was observed on BMI and visceral obesity.
Increased cardiovascular mortality in people with schizophrenia: a 24-year national register study
Authors: Westman J. , Eriksson S. V. , Gissler M. , Hällgren J. , Prieto M. L. , Bobo W. V. , Frye M. A. , Erlinge D. , Alfredsson L. , Ösby U. 
Published: June 2017

AimsPeople who have schizophrenia die earlier from somatic diseases than do people in the general population, but information about cardiovascular deaths in people who have schizophrenia is limited. We analysed mortality in all age groups of people with schizophrenia by specific cardiovascular diseases (CVDs), focusing on five CVD diagnoses: coronary heart disease, acute myocardial infarction, cerebrovascular disease, heart failure and cardiac arrhythmias. We also compared hospital admissions for CVDs in people who had schizophrenia with hospital admissions for CVDs in the general population.MethodsThis national register study of 10 631 817 people in Sweden included 46 911 people who were admitted to the hospital for schizophrenia between 1 January 1987 and 31 December 2010. Information from national registers was used to identify people who had schizophrenia and obtain data about mortality, causes of death, medical diagnoses and hospitalisations.ResultsCVDs were the leading cause of death in people who had schizophrenia (5245 deaths), and CVDs caused more excess deaths than suicide. The mean age of CVD death was 10 years lower for people who had schizophrenia (70.5 years) than the general population (80.7 years). The mortality rate ratio (MRR) for CVDs in all people who had schizophrenia was 2.80 (95% confidence interval (CI) 2.73–2.88). In people aged 15–59 years who had schizophrenia, the MRR for CVDs was 6.16 (95% CI 5.79–6.54). In all people who had schizophrenia, the MRR for coronary heart disease was 2.83 (95% CI 2.73–2.94); acute myocardial infarction, 2.62 (95% CI 2.49–2.75); cerebrovascular disease, 2.4 (95% CI 2.25–2.55); heart failure, 3.25 (95% CI 2.94–3.6); and cardiac arrhythmias, 2.06 (95% CI 1.75–2.43). Hospital admissions for coronary heart disease were less frequent in people who had schizophrenia than in the general population (admission rate ratio, 0.88 (95% CI 0.83–0.94). In all age groups, survival after hospital admission for CVD was lower in people who had schizophrenia than in the general population.ConclusionsPeople who had schizophrenia died 10 years earlier from CVDs than did people in the general population. For all five CVD diagnoses, mortality risk was higher for those with schizophrenia than those in the general population. Survival after hospitalisation for CVDs in people who had schizophrenia was comparable with that of people in the general population who were several decades older.
The Spanish-Version of the Subjective Vitality Scale: Psychometric Properties and Evidence of Validity
Authors: Castillo Isabel , Tomás Inés , Balaguer Isabel 
Published: June 2017

AbstractThe Subjective Vitality Scale (SVS) assess the subjective experience of being full of energy and alive, a clinically relevant outcome measure of positive psychological well-being. The purpose of this paper was to translate the 7-item SVS into Spanish and examine its psychometric properties. In Study 1 (n= 790 adolescents) and Study 2 (n= 130 athletes) reliability and exploratory factor analysis (EFA) were carried out. In Study 1 and Study 3 (n= 197 dancers) evidence of validity of inferences based on SVS scores estimating relationships with other variables (life satisfaction, global self-esteem and emotional and physical exhaustion) was obtained. In Study 2 invariance across time was tested. Finally in Study 3, the factorial structure was cross-validated using confirmatory factor analysis (CFA). Results of EFA showed a one-factor solution. CFA also supported a unidimensional factor structure for the Spanish 6-item SVS (RMSEA = .050 (90% CI = .00, .080); NNFI = .993; CFI = .996). Reliability analysis indicated a strong internal consistency in all study samples (α ranged from .82 to .89). Further, results from multi-sample analysis supported the replicability of SVS factor structure across time. Finally, the SVS scores showed the expected correlations patterns (all them significant,p< .01) with the measured outcomes. In conclusion, the Spanish version of the SVS demonstrated adequate psychometric properties, indicating that the scale can be confidently used to measure the experience of possessing energy and aliveness; furthermore, differences across time can be meaningfully carried out.
Possible Associations between Subitizing, Estimation and Visuospatial Working Memory (VSWM) in Children
Authors: Formoso Jesica , Barreyro Juan Pablo , Jacubovich Silvia , Injoque-Ricle Irene 
Published: June 2017

AbstractResearchers have focused on identifying the mechanisms involved in subitizing and its differences with estimation. Some suggest that subitizing relies on a visual indexing system in charge of the simultaneous individuation of objects that is also used by visuospatial working memory (VSWM). In adults, studies found associations between subitizing and VSWM, in the absence of correlation between VSWM and estimation. The present study analyzed the performance of 120 4 and 6-year-old children in three tasks: dot enumeration to measure subitizing capacity, quantity discrimination for estimation, and Corsi Block-tapping task for VSWM. In the enumeration task RTs (F(9, 1062)=720.59, MSE=734394, p<.001, η2=.86) and errors (F(9, 1062)=42.15, MSE=.194, p<.001, η2=.26.) increased with the array, but this growth was statistically significant only from 4 dots onward. Each subject’s subitizing range was estimated by fitting RTs with a sigmoid function of number of dots and obtaining the bend point of the curve. Data fit (age 4: R2 = .88; SD = .08; age 6: R2 = .91, SD = .08) showed a mean subitizing range of 2.79 (SD = .66) for 4 year-olds and of 3.11 (SD = .64) for 6 year-olds. Subitizing ranges and average RTs showed low association with storage (r = .274; p < .05; r = –.398; p < .001) and average RTs with concurrent processing (r = –.412; p < .001) in VSWM. Subitizing range and speed showed no association with estimation speed and a poor association with accuracy (r = .234, p < .01; r = –.398, p < .001), which suggests independent systems for small and large quantities. Subitizing and estimation measures correlated with VSWM (p < .01), which suggests that both processes may require VSWM resources.
Free-standing supramolecular hydrogel objects by reaction-diffusion
Authors: Lovrak Matija , Hendriksen Wouter E. J. , Maity Chandan , Mytnyk Serhii , van Steijn Volkert , Eelkema Rienk , van Esch Jan H. 
Published: June 2017

AbstractSelf-assembly provides access to a variety of molecular materials, yet spatial control over structure formation remains difficult to achieve. Here we show how reaction–diffusion (RD) can be coupled to a molecular self-assembly process to generate macroscopic free-standing objects with control over shape, size, and functionality. In RD, two or more reactants diffuse from different positions to give rise to spatially defined structures on reaction. We demonstrate that RD can be used to locally control formation and self-assembly of hydrazone molecular gelators from their non-assembling precursors, leading to soft, free-standing hydrogel objects with sizes ranging from several hundred micrometres up to centimeters. Different chemical functionalities and gradients can easily be integrated in the hydrogel objects by using different reactants. Our methodology, together with the vast range of organic reactions and self-assembling building blocks, provides a general approach towards the programmed fabrication of soft microscale objects with controlled functionality and shape.
Ultrathin metal-organic framework array for efficient electrocatalytic water splitting
Authors: Duan Jingjing , Chen Sheng , Zhao Chuan 
Published: June 2017

AbstractTwo-dimensional metal-organic frameworks represent a family of materials with attractive chemical and structural properties, which are usually prepared in the form of bulk powders. Here we show a generic approach to fabricate ultrathin nanosheet array of metal-organic frameworks on different substrates through a dissolution–crystallization mechanism. These materials exhibit intriguing properties for electrocatalysis including highly exposed active molecular metal sites owning to ultra-small thickness of nanosheets, improved electrical conductivity and a combination of hierarchical porosity. We fabricate a nickel-iron-based metal-organic framework array, which demonstrates superior electrocatalytic performance towards oxygen evolution reaction with a small overpotential of 240 mV at 10 mA cm−2, and robust operation for 20,000 s with no detectable activity decay. Remarkably, the turnover frequency of the electrode is 3.8 s−1 at an overpotential of 400 mV. We further demonstrate the promise of these electrodes for other important catalytic reactions including hydrogen evolution reaction and overall water splitting.
Quasilinear quantum magnetoresistance in pressure-induced nonsymmorphic superconductor chromium arsenide
Authors: Niu Q. , Yu W. C. , Yip K. Y. , Lim Z. L. , Kotegawa H. , Matsuoka E. , Sugawara H. , Tou H. , Yanase Y. , Goh Swee K. 
Published: June 2017

AbstractIn conventional metals, modification of electron trajectories under magnetic field gives rise to a magnetoresistance that varies quadratically at low field, followed by a saturation at high field for closed orbits on the Fermi surface. Deviations from the conventional behaviour, for example, the observation of a linear magnetoresistance, or a non-saturating magnetoresistance, have been attributed to exotic electron scattering mechanisms. Recently, linear magnetoresistance has been observed in many Dirac materials, in which the electron–electron correlation is relatively weak. The strongly correlated helimagnet CrAs undergoes a quantum phase transition to a nonmagnetic superconductor under pressure. Here we observe, near the magnetic instability, a large and non-saturating quasilinear magnetoresistance from the upper critical field to 14 T at low temperatures. We show that the quasilinear magnetoresistance may arise from an intricate interplay between a nontrivial band crossing protected by nonsymmorphic crystal symmetry and strong magnetic fluctuations.