bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptation of New Colombian Food-based Complementary Feeding Recommendations Using Linear Programming
Authors: Tharrey Marion , Olaya Gilma A. , Fewtrell Mary , Ferguson Elaine 
Published: June 2017

ABSTRACTObjective:The aim of the study was to use linear programming (LP) analyses to adapt New Complementary Feeding Guidelines (NCFg) designed for infants aged 6 to 12 months living in poor socioeconomic circumstances in Bogota to ensure dietary adequacy for young children aged 12 to 23 months.Design:A secondary data analysis was performed using dietary and anthropometric data collected from 12-month-old infants (n = 72) participating in a randomized controlled trial. LP analyses were performed to identify nutrients whose requirements were difficult to achieve using local foods as consumed; and to test and compare the NCFg and alternative food-based recommendations (FBRs) on the basis of dietary adequacy, for 11 micronutrients, at the population level.Results:Thiamine recommended nutrient intakes for these young children could not be achieved given local foods as consumed. NCFg focusing only on meat, fruits, vegetables, and breast milk ensured dietary adequacy at the population level for only 4 micronutrients, increasing to 8 of 11 modelled micronutrients when the FBRs promoted legumes, dairy, vitamin A–rich vegetables, and chicken giblets. None of the FBRs tested ensured population-level dietary adequacy for thiamine, niacin, and iron unless a fortified infant food was recommended.Conclusions:The present study demonstrated the value of using LP to adapt NCFg for a different age group than the one for which they were designed. Our analyses suggest that to ensure dietary adequacy for 12- to 23-month olds these adaptations should include legumes, dairy products, vitamin A–rich vegetables, organ meat, and a fortified food.
Breathlessness in the primary care setting
Authors: Baxter Noel 
Published: June 2017

Purpose of review
Breathlessness is a high-volume problem with 10% of adults experiencing the symptom daily placing a heavy burden on the health and wider economy. As it worsens, they enter the specialist and hospital-based symptom services where costs quickly escalate and people may find themselves in a place not of their choosing. For many, their care will be delivered by a disease or organ specialist and can find themselves passing between physicians without coordination for symptom support. General practitioners (GPs) will be familiar with this scenario and can often feel out of their depth. Recent advances in our thinking about breathlessness symptom management can offer opportunities and a sense of hope when the GP is faced with this situation.

Recent findings
Original research, reviews and other findings over the last 12–18 months that pertain to the value that general practice and the wider primary care system can add, include opportunities to help people recognize they have a problem that can be treated. We present systems that support decisions made by primary healthcare professionals and an increasingly strong case that a solution is required in primary care for an ageing and frail population where breathlessness will be common.

Summary
Primary care practitioners and leaders must start to realize the importance of recognizing and acting early in the life course of the person with breathlessness because its impact is enormous. They will need to work closely with public health colleagues and learn from specialists who have been doing this work usually with people near to the end of life translating the skills and knowledge further upstream to allow people to live well and remain near home and in their communities.
The effects of ownership structure on likelihood of financial distress: an empirical evidence
Authors: Udin Shahab , Khan Muhammad Arshad , Javid Attiya Yasmin 
Published: June 2017

PurposeThe purpose of this paper is to explore the role of corporate governance proxies by ownership structure on the likelihood of firms’ financial distress for a sample of 146 Pakistani public-limited companies listed at the Karachi Stock Exchange over the period of 2003-2012.Design/methodology/approachThe dynamic generalized method of moments (GMM) estimator and panel logistic regression (PLR) are used to determine the impact of corporate governance on the financial distress. The ownership structure is used as a determinant of corporate governance, while the AltmanZ-score is utilized as an indicator of financial distress, as it measures financial distress inversely. The smaller the values of theZ-score, the higher will be the risk of financial distress.FindingsThe authors find insignificant impact of ownership structure on firms’ likelihood of financial distress based on the dynamic GMM method. However, the PLR results indicate that foreign shareholdings have a significant negative association with firms’ likelihood of financial distress, in the case of Pakistan. An evidence of a negative and insignificant relationship between institutional ownership and financial distress was observed, which indicates the passive role of institutional investors in Pakistan. The results also reveal a positive and significant relationship between insider’s ownership and likelihood of financial distress. This finding is consistent with the entrenchment hypothesis which predicts that insiders are more aligned with their self-interest than outside shareholders’ interest when their shareholding increases in the business. Furthermore, the results also reveal insignificant association between government shareholdings and the probability of financial distress. The reason could be the social welfare objective of the government entities rather than profit maximization.Practical implicationsThe findings of this study provide more insight to corporate managers and investors about the association between the quality of corporate governance and the degree of financial distress, with respect to Pakistani firms. Furthermore, this study contributes to the existing literature by adding new evidence from developing countries like Pakistan which are helpful for regulatory bodies and policymakers in the formulation of long-term corporate governance strategies to manage the financial distress. It is well established that strengthening the quality of corporate governance practices enhances the efficiency of capital markets and reduces the probability of financial distress.Originality/valueThe study extends the body of existing literature on corporate governance and the likelihood of financial distress with reference to Pakistan. The results suggest that policymakers may pay special attention to the quality of corporate governance, specifically ownership structure, while predicting corporate financial distress.
Corporate governance and greenhouse gas disclosure: a mixed-methods approach
Authors: Chithambo Lyton , Tauringana Venancio 
Published: June 2017

PurposeThe purpose of this paper is to investigate whether four corporate governance mechanisms (board size, non-executive directors, ownership concentration and directors’ share ownership) influence the extent of greenhouse gas (GHG) disclosure.Design/methodology/approachThe study uses a mixed-methods approach based on a sample of 62 FTSE 1,000 firms. Firstly, the authors surveyed the senior management of 62 UK-listed firms in the FTSE 1,000 index to determine whether the corporate governance mechanisms influence their GHG disclosure decisions. Secondly, the authors used ordinary least squares (OLS) regression to model the relationship between the corporate governance mechanisms and GHG disclosure scores of the 62 firms.FindingsThe survey and OLS regression results both suggest that corporate governance mechanisms (board size and NEDs) do not influence GHG disclosures. However, the results of the two approaches differ, in that the survey results suggest that corporate governance mechanisms (ownership concentration and directors’ share ownership) do not influence the extent of GHG disclosure, while the opposite is true with the OLS regression results.Research limitations/implicationsThe sample size of 62 firms is small which could affect the generalisability of the study. The mixed results mean that more mixed-methods approach is needed to improve the understanding of the role of corporate governance in GHG disclosures.Originality/valueThe use of mixed-methods to examine whether corporate governance mechanisms determine the extent of GHG voluntary disclosure provides additional insights not provided in prior studies.
How transformational leadership supports knowledge sharing
Authors: Le Phong Ba , Lei Hui 
Published: June 2017

PurposeThis paper aims to clarify the influences of transformational leadership (TL), aspects of justice and trust on knowledge sharing (KS) process after assessing the controlling role of individuals’ education and gender.Design/methodology/approachStructural equations modeling (SEM) has been applied to evaluate the degree of influence that each variable has on the others through using data collected from 353 respondents of 56 large manufacturing and service firms.FindingsThe results show that distributive justice, procedural justice and trust in leadership play mediating roles in the relationship between TL and KS behavior. TL and procedural justice have more significant effects on knowledge collecting, while trust in the leader and distributive justice have more significant effects on knowledge donating.Research limitations/implicationsFuture research can investigate how personal characteristics (e.g. educational level and work experience) may play moderating roles in the relationships between TL and KS processes.Practical implicationsFrom a practical perspective, the study brings a deeper understanding for directors and managers about the necessary factors to encourage and promote KS behavior in the organization.Originality/valueThe study findings provide a theoretical basis that can be used to analyze the relationships between TL, aspects of justice, trust and the KS process.
Alternative Kriging-HDMR optimization method with expected improvement sampling strategy
Authors: Li Enying , Ye Fan , Wang Hu 
Published: June 2017

Purpose
The purpose of study is to overcome the error estimation of standard deviation derived from Expected improvement (EI) criterion. Compared with other popular methods, a quantitative model assessment and analysis tool, termed high-dimensional model representation (HDMR), is suggested to be integrated with an EI-assisted sampling strategy.

Design/methodology/approach
To predict standard deviation directly, Kriging is imported. Furthermore, to compensate for the underestimation of error in the Kriging predictor, a Pareto frontier (PF)-EI (PFEI) criterion is also suggested. Compared with other surrogate-assisted optimization methods, the distinctive characteristic of HDMR is to disclose the correlations among component functions. If only low correlation terms are considered, the number of function evaluations for HDMR grows only polynomially with the number of input variables and correlative terms.

Findings
To validate the suggested method, various nonlinear and high-dimensional mathematical functions are tested. The results show the suggested method is potential for solving complicated real engineering problems.

Originality/value
In this study, the authors hope to integrate superiorities of PFEI and HDMR to improve optimization performance.
Characteristics of innovation orientations in construction companies
Authors: Yusof Nor’Aini , Lai Kong Seng , Mustafa Kamal Ernawati 
Published: June 2017

PurposeAn organisation’s performance tends to be associated with its innovativeness. However, innovation remains challenging in the construction industry, partially due to the complex nature of this industry. Nevertheless, innovation orientations (i.e. creation and adoption) shed new light on innovation in the construction industry. These orientations are similar but not entirely identical. Although most studies do not discuss these orientations in any detail, this study aims to classify the characteristics of the innovation orientations and determines the state of innovation among construction companies in Malaysia.Design/methodology/approachA survey questionnaire was mailed to 1,230 construction companies in Malaysia. Descriptive analysis was used to examine the respondents’ profiles, and factor analysis was used to classify the innovation orientation characteristics. A paired samplest-test was used to determine the state of innovation among the construction companies.FindingsInnovation creation reflects a pioneer’s efforts and involves being a market explorer that tolerates risk and is research and development (R&D)-oriented, whereas innovation adoption involves being a creative imitator, a market follower and a safe player. Construction companies in Malaysia are innovation adoption–oriented.Research limitations/implicationsThis study uses quantitative methods only; therefore, the findings are statistically oriented. The small sample size makes generalisation challenging, so this study reflects only the built environment of the developing country of Malaysia.Originality/valueThis study classifies the characteristics of innovation creation and innovation adoption with respect to the innovation orientation of construction companies in Malaysia.
Managing occupational stress of professionals in large construction projects
Authors: De Silva Nayanthara , Samanmali Rasika , De Silva Harsha Lal 
Published: June 2017

Purpose
Occupational stress among professionals in construction industry is increasing considerably due to faster economic development projects in many developing countries. Reportedly, construction professionals are the third most affected group after miners and police officers. Hence, the study aims to explore profession-specific occupational stressors, their impact on professional and the prevention strategies in place at an organizational level. The study is further focused to identify specific prevention strategies that can be implemented at the organizational level.

Design/methodology/approach
A questionnaire-based survey was performed among construction professionals such as project managers, engineers and quantity surveyors involved in large construction projects to identify occupational stress causing factors pertinent to construction professionals, their impact and occupational stress prevention strategies. Stress prevention strategies at primary, secondary and tertiary levels were analyzed to establish the stress prevention framework for large organizations.

Findings
Eleven occupational stress causing factors were identified to be significant in creating negative impact at work. Further, 13 resultant impacts of negative stress were recognized. Three primary prevention strategies, three secondary prevention strategies and a tertiary prevention approach were identified using a factor analysis to manage these occupational stresses at the organizational level.

Originality/value
Impact of occupational stress on construction professionals that may cause poor performance of the industry can be controlled by effectively managing and controlling the negative stresses.
Pyoderma gangrenosum and underlying diseases in Japanese patients: A regional long‐term study
Authors: Inoue Sae , Furuta Jun‐ichi , Fujisawa Yasuhiro , Onizawa Saori , Ito Shusaku , Sakiyama Masayuki , Kobayashi Keiko , Kanou Toshiyuki , Iijima Shigeruko , Ohi Tsunao , Okubo Chimaki , Moriyama Yoshihiro , Okiyama Naoko , Fujimoto Manabu 
Published: June 2017

AbstractPyoderma gangrenosum (PG) is a chronic inflammatory disease of unknown cause that presents as an inflammatory and ulcerative disorder of the skin. PG is often associated with an underlying systemic disease. However, the frequencies of the underlying diseases are unclear in Japanese patients. In this retrospective, observational study, all patients diagnosed with PG who visited dermatology departments of nine regional hospitals in and around Ibaraki Prefecture were collected from 1982 to 2011 or 2014. The diagnoses of PG were based on the characteristic clinical and histological appearances and ruling out of infection. Sixty‐two PG patients, including 29 males and 33 females, were identified. The ages of onset were 16–89 years, and the mean age was 50.2 years. Fifty (80%) of the 62 patients presented with an ulcerative PG, and the lower leg was the most common site (74%). Forty‐six (74%) PG patients had underlying diseases. The most frequent was ulcerative colitis (32%), followed by myelodysplastic syndrome (11%), rheumatoid arthritis (6%) and aortitis syndrome (5%). For treatment, 54 cases (87%) received systemic corticosteroids and 10 received additional treatment with cyclosporin. There was no significant correlation between underlying diseases and response to the initial treatment. Multivariate analysis revealed that the number of affected sites negatively correlated with successful initial treatment. Fifteen (24%) of the 62 cases relapsed. In conclusion, ulcerative colitis and hematological disorders were frequently associated with PG while approximately a quarter of the cases were idiopathic.
Association of recent gay‐related stressful events and emotional distress with suicidal behaviors over 12 months in Chinese men who have sex with men
Authors: Yu Liya , Li Yanxia , Liu Li , Li Shuang , Na Jun , An Xiaoxia , Zhou Yan , Gu Yuan , Bi Xuejuan , Mu Huijuan , Zhang Rui , Dong Wen , Pan Guowei 
Published: June 2017

AbstractIntroductionThe study was designed to assess the association of gay‐related stressful events (GRSEs) and emotional distress with suicidal behaviors over a 12‐month period in Chinese men who have sex with men (MSM).MethodsA total of 807 MSM were recruited using a respondent‐driven sampling method from 4 cities in northeastern China. The GRSEs were measured using the Gay‐related Stressful Life Events Scale, depression using the Self‐rating Depression Scale, and anxiety using the Self‐rating Anxiety Scale.ResultsA total of 26.0% of study participants experienced GRSEs during the 3 months, and their average Self‐rating Depression Scale and Self‐rating Anxiety Scale scores were significantly lower than the national norms. Over a 12‐month period, the prevalence of suicidal ideation, plan, and attempt was 9.7%, 4.0%, and 3.0%, respectively, each of which is at least 3 to 4 times greater than that of male adults in the general population of China. Multiple logistic regression analysis showed that GRSEs significantly increased the risk of suicidal ideation (odds ratio [OR] = 2.3, 95% confidence interval [CI], 1.4‐3.7) and plan (OR = 2.8, 95% CI, 1.3‐6.0). Depressive symptoms significantly increased the risk of suicidal ideation (OR = 3.5, 95% CI, 2.1‐5.8), plan (OR = 4.4, 95% CI, 2.0‐9.6), and attempt (OR = 5.6, 95% CI, 21.94.8). Anxiety symptoms (OR = 3.4, 95% CI, 1.4‐8.4) and cohabitation with a same sex partner (OR = 3.0, 95% CI, 1.2‐7.9) significantly increased the risk of suicide attempt.DiscussionMore efforts to reduce GRSE are worth investigating as a strategy to reduce suicidal thoughts and behaviors in Chinese MSM.
Enucleation of solid pseudopapillary tumor with a preoperative nasopancreatic drainage stent in a child
Authors: Tanaka Keiichiro , Misawa Takeyuki , Haruki Koichiro , Saito Ryota , Gocho Takeshi , Akiba Tadashi 
Published: June 2017

AbstractSolid pseudopapillary tumor (SPT) is a rare pancreatic tumor with low‐grade malignancy in children. A complete surgical resection can achieve a favorable prognosis. Although several reports have indicated that enucleation is considered a safe and effective treatment, the most significant complication is injury to the main pancreatic duct. The usefulness and safety of tumor enucleation after preoperative placement of an endoscopic nasopancreatic drainage stent (NPDS) has recently been reported. We present the case of SPT in a 10‐year‐old girl. To avoid and detect injury to the main pancreatic duct during operation, an NPDS was endoscopically placed before laparotomy. The patient underwent a complete enucleation of the tumor with the guidance of an NPDS. Our case is the first report of a successful enucleation of an SPT with a preoperative placement of an NPDS. This procedure may lead to safe enucleation of a pancreatic tumor with low malignancy, such as SPT, in children.
A phase I trial of PRN1008, a novel reversible covalent inhibitor of Bruton's tyrosine kinase, in healthy volunteers
Authors: Smith Patrick F. , Krishnarajah Janakan , Nunn Philip A. , Hill Ron J. , Karr Dane , Tam D. , Masjedizadeh Mohammad , Funk Jens O. , Gourlay Steve G. 
Published: June 2017

AimTo evaluate the safety, tolerability, and pharmacokinetics/pharmacodynamics of PRN1008, a novel Bruton's tyrosine kinase (BTK) inhibitor, in healthy volunteers, and thus determine the dose range for future clinical studies.MethodsThis was a two‐part randomized, placebo controlled study in healthy volunteers using a liquid formulation. Part I was a single ascending dose design with dose levels of 50–1200 mg (n = 6 active, two placebos per cohort); Part II was a multiple ascending dose design, with dose regimens ranging from 300 to 900 mg daily, either four times or twice daily for 10 days. Plasma pharmacokinetics, adverse events, vital signs, electrocardiograms and laboratory parameters were assessed. BTK occupancy in peripheral blood mononuclear cells was evaluated as a marker of target engagement.ResultsPRN1008 was rapidly absorbed following oral administration, and was safe and well tolerated in all dose regimens evaluated in both single and multiple doses. PRN1008 demonstrated a large volume of distribution, and a half‐life of approximately 3–4 h. BTK occupancy of >90% was observed within 4 h after dosing in both single and multiple dose regimens, and was closely linked to maximum plasma concentration. BTK occupancy decay was slow (–1.6% h–1), and occupancy was sustained despite drug concentrations being undetectable. No severe or serious adverse events occurred, and the most common adverse events were gastrointestinal in nature.ConclusionsPRN1008 was safe and well‐tolerated following oral administration, and achieved high, sustained levels of BTK occupancy in peripheral blood mononuclear cells.