bluuebunny/crossref_metadata_2025_split huggingface dataset:
Informing synthetic passive microwave predictions through Bayesian deep learning with uncertainty decomposition
Authors: Ortiz Pedro , Casas Eleanor , Orescanin Marko , Powell Scott W. , Petkovic Veljko 
Published: September 2024

Abstract
Space-borne passive microwave (PMW) data provide rich information on atmospheric state, including cloud structure and underlying surface properties. However, PMW data are sparse and limited due to low Earth orbit collection, resulting in coarse Earth system sampling. This study demonstrates that Bayesian deep learning (BDL) is a promising technique for predicting synthetic microwave (MW) data and its uncertainties from more ubiquitously available geostationary infrared observations. Our BDL models decompose predicted uncertainty into aleatoric (irreducible) and epistemic (reducible) components, providing insights into uncertainty origin and guiding model improvement. Low and high aleatoric uncertainty values are characteristic of clear sky and cloudy regions, respectively, suggesting that expanding the input feature vector to allow richer information content could improve model performance. The initially high average epistemic uncertainty metrics quantified by most models indicate that the training process would benefit from a greater data volume, leading to improved performance at most studied MW frequencies. Using quantified epistemic uncertainty to select the most useful additional training data (a training dataset size increase of 3.6%), the study reduced the mean absolute error and root mean squared error by 1.74% and 1.38%, respectively. The broader impact of this study is the demonstration of how predicted epistemic uncertainty can be used to select targeted training data. This allows for the curation of smaller, more optimized training datasets and also allows for future active learning studies.
Understanding the fluvial capture of the Guadix-Baza Basin in SE Spain through its oldest exorheic deposits
Authors: García-Tortosa Francisco J. , Alfaro Pedro , Martin-Rojas Iván , Medina-Cascales Iván , Giralt Santiago 
Published: September 2024

AbstractThe fluvial capture of endorheic basins represents a milestone in basin chronology, implying a profound disequilibrium that triggers critical geomorphological, sedimentological, paleogeographic, and even paleoecological transformations. The primary goal of many geomorphological studies is to determine the timing of endorheic-to-exorheic transitions with the objective of unveiling the dynamics that follow the capture event. The age of the Guadix-Baza Basin capture in the Central Betic Cordillera (S Spain) remains a subject of controversy, with proposed estimates ranging from 17 to 600 ka. In this study, we present new 234U/230Th and optically stimulated luminescence ages from exorheic deposits exposed within the basin's main fluvial valley, the Guadiana Menor River. We acquired the oldest numerical age recorded to date for a postcapture deposit within the basin. This age corresponds to a travertine platform formed 240.8 ± 25 ka on a surface level that was already incised into the glacis surface at approximately 250 m. Using these data, we estimate that basin capture took place earlier than ca. 240 ka, plus the time required for the river to incise 250 m to the position of the travertine. Furthermore, the proximity of the Matuyama-Brunhes reversal (781 ka) to the top of the endorheic succession and the ages of the paleontological sites (> ca. 750 ka) throughout the basin suggest that the capture could have occurred earlier than the oldest previously proposed age of 600 ka.
Survival study of enteral and parenteral nutrition pathways in critically ill patients receiving vasopressors: an analysis of the Medical Information Mart for Intensive Care-IV database
Authors: Sun Aqiao , Li Minling , Song Ye , Song Yinxue , Nan Jiayan 
Published: September 2024

AbstractThis study compared survival outcomes between intensive care unit (ICU) patients receiving enteral nutrition (EN) and parenteral nutrition (PN) with vasopressor support, explored risk factors affecting clinical outcomes and established an evaluation model. Data from 1046 ICU patients receiving vasopressor therapy within 24 h from 2008 to 2019 were collected. Patients receiving nutritional therapy within 3 d of ICU admission were divided into EN or PN (including PN+EN) groups. Cox analysis and regression were used to determine relevant factors and establish a nomogram for predicting survival. The 28-d survival rate was significantly better in the EN group compared with the PN/PN+EN group. Risk factors included age, peripheral capillary oxygen saturation, red cell distribution width, international normalised ratio, potassium level, mean corpuscular Hg, myocardial infarction, liver disease, cancer status and nutritional status. The nomogram showed good predictive performance. In ICU patients receiving vasopressor drugs, patients receiving EN had a better survival rate than PN. Our nomogram had favourable predictive value for 28-d survival in patients. However, it needs further validation in prospective trials.
The Pangolin Universal Notching System: a scale-marking methodology for pangolins
Authors: Martin Jeannie Miller , Buckley Jacqueline Y. , Connelly Ellen , Hywood Lisa , Lacey L. Mae , Ruden Rachel M. , Ruhagazi Deo , Wearn Anna 
Published: September 2024

Abstract
Despite thousands of individuals entering the illegal wildlife trade each year, assessments of pangolin populations are largely non-existent, even in areas with high exploitation and limited personnel and field equipment. Although pangolins have unique keratin-based scales, there is no universal scale-marking method for individuals despite some pangolin conservation programmes utilizing marking for reference and cataloguing. Each programme currently establishes and manages its own system, resulting in inconsistencies and limiting data sharing. To facilitate pangolin monitoring and research, we developed a standardized method for assigning individual identification numbers, which we call the Pangolin Universal Notching System. This system is neither resource nor training intensive, which could facilitate its adoption and implementation globally. Its application could help to address knowledge gaps in pangolin ageing, reproduction, survivorship, migration and local trafficking patterns, and could be used in combination with other tagging techniques for research on pangolin biology.
Listening to Mapuche sound in Illapu
Authors: Jordán González Laura 
Published: September 2024

AbstractThis article studies how Illapu, a prominent Chilean New Song band, deals with Mapuche culture and sound. Through the analysis of four songs, I argue that by first incorporating Mapuche instruments and rhythms (1970s), and then adding engaged lyrics dealing with Mapuche history (1980s), and finally engaging with Mapuche listeners and artists (1990s–2000s), Illapu participates in the transformation of the way in which indigeneity is conceived. I assert that the transformation of their creative processes takes place in parallel with the emergence of a public political Mapuche subject distinctly identified as such. By positioning themselves as ‘brown’ exemplary agents, the members of Illapu get to voice current Mapuche political demands without resorting to supplantation.
Eastern Spirituality
Authors: Zacharias H. C. E. 
Published: September 2024

Paganism, that is ethnic religions, can only be understood historically.
They are the precipitate of a tribe's, a people's, group-experiences during
its process of formation. They are passed on from generation to generation
by way of tradition and are expressed either as customs, as mythology or as
cult—the distinction between these three kinds of thoughts, words and deeds
always remaining pretty vague. Moreover, all these group-expressions are in
a constant flux; new experiences are added, modifying and perhaps logically
contradicting, the previous forms of expression, possibly superseding them
altogether.
Nothing, therefore, could be more misleading than wanting to explain a
pagan ideology, an ethnic religion, in the same manner as that of a religion
based on a depositum fidei, from which everything
can be logically deduced. An ethnic religion never starts as a system,
though in the end, at a certain point of intellectual development,
systematisers arise that try to arrest the growth of amorphous
agglomerations of group-experiences in the rigid moulds of a static
ideology.
Life Through the Cross
Authors: Foster Paul 
Published: September 2024

In a famous picture of the Crucifixion the Cross is depicted soaring
against a dark background of cloud, over the quiet waters of Genesareth—it
recalls that moment when the Lord awakened from slumber in the heart of the
storm and spoke the words … ‘peace, be still’ … and immediately there was a
great calm.
It may have happened to many of you, as it happened to the disciples on
Peter's ship, to undergo a moment of great physical distress, to be lost in
the cloud or the desert, to have the sea raging about you, to see no way out
from a lingering disease. Such moments of physical imprisonment are
paralleled by spiritual distress, the soul in a state of utter loneliness
and desolation … ‘My God, why hast thou forsaken me?’ There is no harbour
visible, no landmark, no sense of direction; only barren snow or solitary
sand, indifferent glances, the howling of air or sea.
The relationship between perfectionism and self-esteem in adults: a systematic review and meta-analysis
Authors: Khossousi Viyona , Greene Danyelle , Shafran Roz , Callaghan Thomas , Dickinson Sheree , Egan Sarah J. 
Published: September 2024

AbstractBackground:Perfectionism dimensions, including perfectionistic strivings and perfectionistic concerns, have a significant positive association with psychopathology. Clinical perfectionism is defined as when an individual’s self-esteem is excessively reliant on meeting high standards despite negative consequences. Numerous studies have found that higher perfectionistic concerns correlate with lower self-esteem; however, evidence for the association with perfectionistic strivings has been mixed.Aims:The focus of this systematic review and meta-analysis was to inform theoretical understanding of the relationships between perfectionism dimensions and self-esteem in adults.Method:A systematic literature search was conducted in Medline, PsycINFO, PsychARTICLES, ProQuest Central, and Scopus on 31 May 2023.Results:There were 83 articles included, with 32,304 participants (Mage=∼24.66 years). There was a significant negative moderate pooled association between self-esteem and perfectionistic concerns, r=–.42, 95% CI [–0.47 to –0.38]. A significant negligible positive pooled association was found between self-esteem and perfectionistic strivings, r=.06, 95% CI [0.01 to 0.11]. Results indicate higher perfectionistic concerns is associated with lower self-esteem, providing indirect support for the cognitive-behavioural model of clinical perfectionism.Conclusions:Future research should compare cognitive behaviour therapy for perfectionism to treatments for low self-esteem on outcomes of perfectionistic concerns and psychopathology.
Kendhang Gaya Selo: Aesthetic Choice and Musical Exchange among Drummers in Central Java
Authors: STANDIFORD HANNAH M. , SUGIYANTO DANIS , SUYOTO  
Published: September 2024

AbstractThe plucked selo, a three-stringed variation of the cello, in langgam Jawa kroncong music was originally inspired by Javanese gamelan kendhang drumming. By the 1960s, however, Ki Nartosabdho had developed a style of kendhang playing that imitates the selo, often called kendhang gaya selo (selo-style drumming), bringing this musical exchange full circle. Not every piece, however, is considered suitable for this rhythmic treatment. In this article, we examine musical exchanges in a song form known as langgam Jawa between the selo and the Javanese kendhang, and investigate when drummers decide to use kendhang gaya selo in gamelan settings.
Residual and Unmodeled Ocean Tide Signal From 20+ Years of GRACE and GRACE‐FO Global Gravity Field Models
Authors: Koch Igor , Duwe Mathias , Flury Jakob 
Published: September 2024

AbstractWe analyze remaining ocean tide signal in K/Ka‐band range‐rate (RR) postfit residuals, obtained after estimation of monthly gravity field solutions from 21.5 years of Gravity Recovery and Climate Experiment (GRACE) and GRACE Follow‐On sensor data. Low‐pass filtered and numerically differentiated residuals are assigned to grids and a spectral analysis is performed using Lomb‐Scargle periodograms. We identified enhanced amplitudes at over 30 ocean tide periods. Spectral replicas revealed several tides from sub‐semidiurnal bands. Increased ocean tide amplitudes are located in expected regions, that is, in high‐latitude, coastal and shallow water regions, although some tides also show distinct patterns over the open ocean. While most identified tides are considered during processing, and therefore the amplitudes represent residual signal w.r.t. the ocean tide model, several unmodeled tides were found, including astronomical degree‐3 tides , , , , and radiational and/or compound tides , , , and . The astronomical degree‐3 tides were observed on a global level for the first time a few years ago in altimeter data. We are unaware of any global data‐constrained solutions for the other tides. The amplitude patterns of these tides exhibit similarities to purely hydrodynamic solutions, and altimeter observations (astronomical degree‐3 only). The sensitivity of the satellites to these rather small tidal effects demands their inclusion into the gravity field recovery processing to reduce orbit modeling errors and a possible aliasing. The conducted study shows enormous potential of RR postfit residuals analysis for validating ocean tide models and improving gravity field recovery processing strategies.
The Interaction Between Climate Forcing and Feedbacks
Authors: Gettelman A. , Eidhammer T. , Duffy M. L. , McCoy D. T. , Song C. , Watson‐Parris D. 
Published: September 2024

AbstractA Perturbed Parameter Ensemble (PPE) with the Community Atmosphere Model version 6 (CAM6) is used to better understand the sensitivity of aerosol forcing and cloud feedbacks to changes in model processes. Aerosol forcing through aerosol‐cloud interactions is mostly negative (a cooling) due to shortwave radiation, while feedbacks are positive or negative in different regions due to contrasting longwave and shortwave effects. Both forcing and feedbacks are related to the mean climate state. Higher magnitude cloud radiative effects generally mean larger magnitude net negative forcing and larger magnitude net positive feedback. Aerosol forcing is broadly related to the susceptibility of clouds to drop number. Feedbacks also related to susceptibility, but to a lesser extent and in different regions to aerosol forcing. Aerosol forcing and cloud feedbacks are anti‐correlated in the CAM6 PPE such that stronger negative forcing is associated with stronger positive feedbacks. Even the processes governing forcing and feedback sensitivity in the PPE are similar. These include the warm rain formation process, ice loss processes and deep convective intensity.
Post-thaw CD34+ cell recovery likely degraded under extreme graft platelet concentrations
Authors: Duarte Gustavo C. , Ladvanszky Leandro , Atkinson Gavin , Burns Michelle , Madola Dona , Sadani Deepak , Yan-Fischer Marcus , Patel Hemant , Tremblay Jacynthe , Butler Andrew , Rathod Niranjan , Wei Wen-Hua 
Published: September 2024

AbstractImpaired post-thaw CD34 cell (postCD34) viability in autologous haematopoietic stem cell transplant (ASCT) could indicate delayed engraftment where multiple factors might complicate the relationship. Despite of a couple of unconfirmed reports of a negative correlation of platelet concentration with postCD34 viability, how platelets might be involved in the relationship is largely unknown. Therefore, this question was addressed in this retrospective study of 82 ASCT patients with a total of 150 collections of peripheral blood stem cells in New Zealand. A significant negative correction between platelet concentration and postCD34 recovery (r = −0.18, p = 0.028) was observed overall, but upon further analysis only confirmed in the subset with graft platelets 1500–2000 ×109/L. Importantly, the postCD34 recovery was clearly reduced in the subgroups with either the lowest or the highest platelet concentration. The lowest subgroup was enriched with collections from patients with Hodgkin or non-Hodgkin lymphoma, whereas the highest subgroup from patients with multiple myeloma, both with clearly male preponderance. We hypothesized that graft platelet concentrations probably indicated CD34 cell state (e.g. cell cycle and cell adhesion highly related to platelet functions) that sustained when platelet concentrations were within a niche range but went out of kilter otherwise.
SPHK1 promotes bladder cancer metastasis via PD-L2/c-Src/FAK signaling cascade
Authors: Kao Wei-Hsiang , Liao Li-Zhu , Chen Yu-An , Lo U-Ging , Pong Rey-Chen , Hernandez Elizabeth , Chen Mei-Chih , Teng Chieh-Lin Jerry , Wang Hsin-Yi , Tsai Stella Chin-Shaw , Kapur Payal , Lai Chih-Ho , Hsieh Jer-Tsong , Lin Ho 
Published: September 2024

AbstractSPHK1 (sphingosine kinase type 1) is characterized as a rate-limiting enzyme in sphingolipid metabolism to phosphorylate sphingosine into sphingosine-1-phosphate (S1P) that can bind to S1P receptors (S1PRs) to initiate several signal transductions leading to cell proliferation and survival of normal cell. Many studies have indicated that SPHK1 is involved in several types of cancer development, however, a little is known in bladder cancer. The TCGA database analysis was utilized for analyzing the clinical relevance of SPHK1 in bladder cancer. Through CRISPR/Cas9 knockout (KO) and constitutive activation (CA) strategies on SPHK1 in the bladder cancer cells, we demonstrated the potential downstream target could be programmed cell death 1 ligand 2 (PD-L2). On the other hand, we demonstrated that FDA-approved SPHK1 inhibitor Gilenya® (FTY720) can successfully suppress bladder cancer metastasis by in vitro and in vivo approaches. This finding indicated that SPHK1 as a potent therapeutic target for metastatic bladder cancer by dissecting the mechanism of action, SPHK1/S1P-elicited Akt/β-catenin activation promoted the induction of PD-L2 that is a downstream effector in facilitating bladder cancer invasion and migration. Notably, PD-L2 interacted with c-Src that further activates FAK. Here, we unveil the clinical relevance of SPHK1 in bladder cancer progression and the driver role in bladder cancer metastasis. Moreover, we demonstrated the inhibitory effect of FDA-approved SPHK1 inhibitor FTY720 on bladder cancer metastasis from both in vitro and in vivo models.
The global geography of artificial intelligence in life science research
Authors: Schmallenbach Leo , Bärnighausen Till W. , Lerchenmueller Marc J. 
Published: September 2024

AbstractArtificial intelligence (AI) promises to transform medicine, but the geographic concentration of AI expertize may hinder its equitable application. We analyze 397,967 AI life science research publications from 2000 to 2022 and 14.5 million associated citations, creating a global atlas that distinguishes productivity (i.e., publications), quality-adjusted productivity (i.e., publications stratified by field-normalized rankings of publishing outlets), and relevance (i.e., citations). While Asia leads in total publications, Northern America and Europe contribute most of the AI research appearing in high-ranking outlets, generating up to 50% more citations than other regions. At the global level, international collaborations produce more impactful research, but have stagnated relative to national research efforts. Our findings suggest that greater integration of global expertize could help AI deliver on its promise and contribute to better global health.
Avoided metallicity in a hole-doped Mott insulator on a triangular lattice
Authors: Yim Chi Ming , Siemann Gesa-R. , Stavrić Srdjan , Khim Seunghyun , Benedičič Izidor , Murgatroyd Philip A. E. , Antonelli Tommaso , Watson Matthew D. , Mackenzie Andrew P. , Picozzi Silvia , King Phil D. C. , Wahl Peter 
Published: September 2024

AbstractDoping of a Mott insulator gives rise to a wide variety of exotic emergent states, from high-temperature superconductivity to charge, spin, and orbital orders. The physics underpinning their evolution is, however, poorly understood. A major challenge is the chemical complexity associated with traditional routes to doping. Here, we study the Mott insulating CrO2 layer of the delafossite PdCrO2, where an intrinsic polar catastrophe provides a clean route to doping of the surface. From scanning tunnelling microscopy and angle-resolved photoemission, we find that the surface stays insulating accompanied by a short-range ordered state. From density functional theory, we demonstrate how the formation of charge disproportionation results in an insulating ground state of the surface that is disparate from the hidden Mott insulator in the bulk. We demonstrate that voltage pulses induce local modifications to this state which relax over tens of minutes, pointing to a glassy nature of the charge order.
Femtosecond pulse amplification on a chip
Authors: Gaafar Mahmoud A. , Ludwig Markus , Wang Kai , Wildi Thibault , Voumard Thibault , Sinobad Milan , Lorenzen Jan , Francis Henry , Carreira Jose , Zhang Shuangyou , Bi Toby , Del’Haye Pascal , Geiselmann Michael , Singh Neetesh , Kärtner Franz X. , Garcia-Blanco Sonia M. , Herr Tobias 
Published: September 2024

AbstractFemtosecond laser pulses enable the synthesis of light across the electromagnetic spectrum and provide access to ultrafast phenomena in physics, biology, and chemistry. Chip-integration of femtosecond technology could revolutionize applications such as point-of-care diagnostics, bio-medical imaging, portable chemical sensing, or autonomous navigation. However, current chip-integrated pulse sources lack the required peak power, and on-chip amplification of femtosecond pulses has been an unresolved challenge. Here, addressing this challenge, we report >50-fold amplification of 1 GHz-repetition-rate chirped femtosecond pulses in a CMOS-compatible photonic chip to 800 W peak power with 116 fs pulse duration. This power level is 2–3 orders of magnitude higher compared to those in previously demonstrated on-chip pulse sources and can provide the power needed to address key applications. To achieve this, detrimental nonlinear effects are mitigated through all-normal dispersion, large mode-area and rare-earth-doped gain waveguides. These results offer a pathway to chip-integrated femtosecond technology with peak power levels characteristic of table-top sources.
Convergent evolution in Afrotheria and non-afrotherians demonstrates high evolvability of the mammalian inner ear
Authors: Grunstra Nicole D. S. , Hollinetz Fabian , Bravo Morante Guillermo , Zachos Frank E. , Pfaff Cathrin , Winkler Viola , Mitteroecker Philipp , Le Maître Anne 
Published: September 2024

AbstractEvolutionary convergence in distantly related species is among the most convincing evidence of adaptive evolution. The mammalian ear, responsible for balance and hearing, is not only characterised by its spectacular evolutionary incorporation of several bones of the jaw, it also varies considerably in shape across modern mammals. Using a multivariate approach, we show that in Afrotheria, a monophyletic clade with morphologically and ecologically highly disparate species, inner ear shape has evolved similar adaptations as in non-afrotherian mammals. We identify four eco-morphological trait combinations that underlie this convergence. The high evolvability of the mammalian ear is surprising: Nowhere else in the skeleton are different functional units so close together; it includes the smallest bones of the skeleton, encapsulated within the densest bone. We suggest that this evolvability is a direct consequence of the increased genetic and developmental complexity of the mammalian ear compared to other vertebrates.