bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Incidence and Evolution of Parkinsonian Rigidity in Rett Syndrome: A Pilot Study
Authors: Humphreys Peter , Barrowman Nick 
Published: April 2016

AbstractBackground: Patients with Rett syndrome (RTT) may demonstrate parkinsonian features. Here, we report a preliminary cross-sectional and prospective evaluation of the evolution, regional distribution, and eventual incidence of rigid tone in a cohort of MECP2 mutation-positive patients. Methods: In 51 participants, muscle tone rigidity in extremity regions and neck plus hypomimia were quantified using an RTT rigidity distribution (RTTRD) score with a range of 0 to 15. RTTRD scores were correlated with age, ability to walk and speak, mutation type, and, in a small subgroup (n=9), cerebrospinal fluid (CSF) homovanillic acid (HVA) and 5-hydroxyindole-acetic acid levels. Results: Participant ages ranged from 2 years and 5 months, to 54 years. Rigidity was found in 43/51 (84.3%); it appeared as early as age 3, increased in extent with age, and was present in all participants aged ≥13. Ankle region rigidity appeared first, followed by proximal legs, arms, neck, and face. Ambulatory participants (n=21) had lower RTTRD scores than nonambulatory (n=30; p=0.003). We found a trend to lower scores in participants with retained speech (n=13) versus those with none (n=38; p=0.074), and no difference in scores for those with truncating (n=25) versus missense mutations (n=22; p=0.387). RTTRD scores correlated negatively with CSF HVA levels (R=−0.83; p=0.005), but not with 5-hydroxyindole-acetic acid levels (R=−0.45; p=0.22). Conclusions: Although assessment of muscle tone is somewhat subjective and the RTTRD has not been validated, this study nevertheless suggests that parkinsonian rigidity in RTT is common and frequently increases in extent with age; its severity correlates directly with impaired ambulation and inversely with CSF HVA levels.
Effects of geometric confinement in quasi-2-D turbulent Rayleigh–Bénard convection
Authors: Huang Shi-Di , Xia Ke-Qing 
Published: April 2016

We report an experimental study of confinement effects in quasi-2-D turbulent Rayleigh–Bénard convection. The experiments were conducted in five rectangular cells with their height $H$ and length $L$ being the same and fixed, while the width $W$ was different for each cell to produce lateral aspect ratios (${\it\Gamma}=W/H$) of 0.6, 0.3, 0.2, 0.15 and 0.1. Direct flow field measurements reveal that the large-scale flow slows down as ${\it\Gamma}$ decreases and there are more plumes travelling through the bulk region. Moreover, the reversal frequency of the large-scale flow is found to increase drastically in smaller ${\it\Gamma}$ cells, by more than 1000-fold for the highest value of Rayleigh number reached in the experiment. The reversal frequency can be well described by a stochastic model developed by Ni et al. (J. Fluid Mech., vol. 778, 2015, R5) and the probability density functions (PDF) of the time interval between successive reversals are found to follow Poisson statistics as in the 3-D system. It is further observed that the bulk temperature fluctuation increases significantly and its PDF changes from exponential to Gaussian as ${\it\Gamma}$ decreases. The influences of geometric confinement on the global heat transport are also investigated. The measured Nu–Ra relationship suggests that, as the lateral aspect ratio decreases, the relative weight of the boundary layer contribution in the global heat transport increases compared to that from the bulk. These results demonstrate that in the quasi-2-D geometry, geometric confinement has strong effects on both the global and local properties in turbulent convective flows, which are very different from the previous findings in 3-D and true 2-D systems.
Simultaneous temperature and velocity Lagrangian measurements in turbulent thermal convection
Authors: Liot O. , Seychelles F. , Zonta F. , Chibbaro S. , Coudarchet T. , Gasteuil Y. , Pinton J.-F. , Salort J. , Chillà F. 
Published: April 2016

We report joint Lagrangian velocity and temperature measurements in turbulent thermal convection. Measurements are performed using an improved version (extended autonomy) of the neutrally buoyant instrumented particle (Shewet al.,Rev. Sci. Instrum., vol. 78, 2007, 065105) that was used by Gasteuilet al.(Phys. Rev. Lett., vol. 99, 2007, 234302) to performed experiments in a parallelepipedic Rayleigh–Bénard cell. The temperature signal is obtained from a radiofrequency transmitter. Simultaneously, we determine a particle’s position and velocity with one camera, which grants access to the Lagrangian heat flux. Due to the extended autonomy of the present particle, we obtain well-converged temperature and velocity statistics, as well as pseudo-Eulerian maps of velocity and heat flux. Present experimental results have also been compared with the results obtained by a corresponding campaign of direct numerical simulations and Lagrangian tracking of massless tracers. The comparison between experimental and numerical results shows the accuracy and reliability of our experimental measurements and points also out the finite-size effects of the particle. Finally, the analysis of Lagrangian velocity and temperature frequency spectra is shown and discussed. In particular, we observe that temperature spectra exhibit an anomalous$f^{-2.5}$frequency scaling, likely representing the ubiquitous passive and active scalar behaviour of temperature.
Resolved Observations of Transition Disks
Authors: Casassus Simon 
Published: April 2016

AbstractResolved observations are bringing new constraints on the origin of radial gaps in protoplanetary disks. The kinematics, sampled in detail in one case-study, are indicative of non-Keplerian flows, corresponding to warped structures and accretion which may both play a role in the development of cavities. Disk asymmetries seen in the radio continuum are being interpreted in the context of dust segregation via aerodynamic trapping. We summarise recent observational progress, and describe prospects for improvements in the near term.
Bayesian Modeling of an Early Bronze Age Cemetery at Armadale, Isle of Skye, Scotland
Authors: Krus Anthony M , Peteranna Mary 
Published: April 2016

AbstractExcavations from 2009–2010 in Armadale, Isle of Skye, Scotland, encountered a burial site with seven cists, pits containing cremation burials, a kerbed cairn, and a small stone and post circle. Twenty-one radiocarbon measurements were taken from single entities of wood charcoal, carbonized residue on pottery, and cremated human bone. A site chronology has been constructed using a Bayesian approach that considers the stratigraphic contexts and feature formation processes. The site was host to thousands of years of discontinuous human activity beginning with little understood Mesolithic and Neolithic components. Modeling estimates that mortuary activity at the site began in the Early Bronze Age in2220–1985 cal BC(95% probability) and to have ended in1880–1660 cal BC(95% probability). The span of activity during this burial component is estimated to be140–520 yr(95% probability) in the primary Bayesian model and50–470 yr(95% probability) in an alternative model. These modeling results demonstrate that human burial at Armadale was an infrequent event and further suggest that the memory of the location and social role of Armadale as a burial ground persisted throughout much of the Early Bronze Age.
Americans' Belief in Linked Fate: Does the Measure Capture the Concept?
Authors: Gay Claudine , Hochschild Jennifer , White Ariel 
Published: April 2016

AbstractFor decades, scholars have attributed Black Americans' unified political and policy views, despite growing internal class and status differences, to a strong perception of linked fate. In recent years, the concept has been measured in other racial and ethnic groups and with regard to gender, but not applied to social statuses such as class or religion. Without broad comparisons across groups and different statuses, however, one cannot determine the appropriate empirical test or most distinctive correlates of this canonical construct. Using a new national survey, we examine Americans' views of linked fate by race or ethnicity, and also by gender, class, or religion. We find expressions of linked fate to be similar across racial or ethnic groups, robust to experimental manipulation, and as strong for class as for racial or ethnic identity. Intra-individual correlations on linked fate items are very high, while a sense of linked fate is rarely associated with political views or political participation. Expressions of linked fate are not always closely related to feelings of closeness to one's group or perceptions of discrimination against that group. We speculate on the broader meaning of responses to this standard item, and conclude that the enormously fruitful theory of racial linked fate is due for further conceptual development and empirical experimentation.
‘MBOKA MUNDELE’: AFRICANITY, RELIGIOUS PLURALISM AND THE MILITARIZATION OF PROPHETS IN BRAZZAVILLE AND KINSHASA
Authors: Demart Sarah , Tonda Joseph 
Published: April 2016

ABSTRACTIn recent decades, Kinshasa and Brazzaville have given rise to movements of prophecy, messianic fervour and revival (Pentecostalist in nature) in the field of religion. The patterns of liberation and deliverance that can be discerned here reflect forms of identity politics in which Africanity, in the ethnic and national sense, is not only a major issue, but a component that is increasingly associated with armed conflict. These processes express a radical paradigm shift that we place within the context of the relationship between Africanity and religious pluralism that has become evident in these two religious areas in recent years. The term ‘Mboka Mundele’ (the village or country of the Whites) points to an experience of ‘colonial modernity’, and allows us to describe in objective terms the current urban context in which these ‘businessmen of God’ emerge. Fernando Kutino, Ntoumi, Yaucat Guendi and Ne Muanda Nsemi are four major politico-religious figures who embody an ideology of Africanity related to complex types of ‘magic’ and processes of pluralization.
Estimating population food and nutrient exposure: a comparison of store survey data with household panel food purchases
Authors: Eyles Helen , Neal Bruce , Jiang Yannan , Ni Mhurchu Cliona 
Published: April 2016

AbstractPopulation exposure to food and nutrients can be estimated from household food purchases, but store surveys of foods and their composition are more available, less costly and might provide similar information. Our aim was to compare estimates of nutrient exposure from a store survey of packaged food with those from household panel food purchases. A cross-sectional store survey of all packaged foods for sale in two major supermarkets was undertaken in Auckland, New Zealand, between February and May 2012. Longitudinal household food purchase data (November 2011 to October 2012) were obtained from the nationally representative, population-weighted New Zealand Nielsen HomeScan® panel. Data on 8440 packaged food and non-alcoholic beverage products were collected in the store survey. Food purchase data were available for 1229 households and 16 812 products. Store survey data alone produced higher estimates of exposure to Na and sugar compared with estimates from household panel food purchases. The estimated mean difference in exposure to Na was 94 (95 % CI 72, 115) mg/100 g (20 % relative difference; P<0·01), to sugar 1·6 (95 % CI 0·8, 2·5) g/100 g (11 %; P<0·01), to SFA −0·3 (95 % CI −0·8, 0·3) g/100 g (6 %; P=0·3) and to energy −18 (−71, 35) kJ/100 g (2 %; P=0·51). Compared with household panel food purchases, store survey data provided a reasonable estimate of average population exposure to key nutrients from packaged foods. However, caution should be exercised in using such data to estimate population exposure to Na and sugar and in generalising these findings to other countries, as well as over time.
A nutrition intervention is effective in improving dietary components linked to cardiometabolic risk in youth with first-episode psychosis
Authors: Teasdale Scott B. , Ward Philip B. , Rosenbaum Simon , Watkins Andrew , Curtis Jackie , Kalucy Megan , Samaras Katherine 
Published: April 2016

AbstractSevere mental illness is characterised by a 20-year mortality gap due to cardiometabolic disease. Poor diet in those with severe mental illness is an important and modifiable risk factor. The present study aimed to (i) examine baseline nutritional intake in youth with first-episode psychosis (FEP), (ii) evaluate the feasibility and acceptability of nutritional intervention early in FEP and (iii) to evaluate the effectiveness of early dietary intervention on key nutritional end points. Participants were recruited over a 12-month period from a community-based programme specifically targeting young people aged 15–25 years with newly diagnosed FEP. Individual dietetic consultations and practical group sessions were offered as part of a broader lifestyle programme. Dietary assessments were conducted before and at the end of the 12-week intervention. Participants exceeded recommended energy and Na intakes at baseline. Retention within the nutrition intervention was 67 %, consistent with other interventions offered to FEP clients. There was a 47 % reduction in discretionary food intake (−94 g/d,P<0·001) and reductions in daily energy (−24 %,P<0·001) and Na (−26 %,P<0·001) intakes. Diet quality significantly improved, and the mean change was 3·6 (95 % CI 0·2, 6·9,P<0·05), although this finding was not significant after Bonferroni’s correction. Increased vegetable intake was the main factor contributing to improved diet quality. Nutrition intervention delivered shortly after initiation of antipsychotic medication is feasible, acceptable and effective in youth with FEP. Strategies to prevent weight gain and metabolic decline will contribute to prevent premature cardiometabolic disease in this vulnerable population.
The Effectiveness of Initiatives to Promote Good Governance, Accountability and Transparency in the Extractives Sector in Zimbabwe
Authors: Murombo Tumai 
Published: April 2016

AbstractThe regulation of the extractives sector in Zimbabwe has recently come under scrutiny due to the uncertain social, economic and political environment. Zimbabwe's mining sector was under colonial legislation for a long time and that legislation has recently been reviewed. Existing extractives sector laws do not adequately promote transparency and accountability, an issue recognized by stakeholders throughout the mining sector. The advent of the new constitution and law reform processes indicates Zimbabwe's intention to incorporate good governance, transparency and accountability provisions in the mining sector. State driven reforms have been inspired by global and local civil society initiatives. Analysis shows that, for various reasons, the government does not readily embrace such initiatives, which are important drivers of official policy and legal reforms. Zimbabwean environmental civil society groups have been exceptional in this regard.
The health of nine Royal Naval Arctic crews, 1848 to 1854: implications for the lost Franklin Expedition
Authors: Millar Keith , Bowman Adrian W. , Battersby William , Welbury Richard R. 
Published: April 2016

ABSTRACTMedical factors including tuberculosis, scurvy, lead poisoning and botulism have been proposed to explain the high death rate prior to desertion of the ships on Sir John Franklin's expedition of 1845–1848 but their role remains unclear because the surgeons’Sick bookswhich recorded illness on board have eluded discovery. In their absence, this study examines theSick booksof Royal Naval search squadrons sent in search of Franklin, and which encountered similar conditions to his ships, to consider whether their morbidity and mortality might reflect that of the missing expedition. TheSick booksof HMSAssistance, Enterprise, Intrepid, Investigator, PioneerandResoluteyielded 1,480 cases that were coded for statistical analysis. On the basis of the squadrons’ patterns of illness it was concluded that Franklin's crews would have suffered common respiratory and gastro-intestinal disorders, injuries and exposure and that deaths might have occurred from respiratory, cardiovascular and tubercular conditions. Scurvy occurred commonly and it was shown that the method of preparing ‘antiscorbutic’ lemon juice for the search squadrons and Franklin's ships would have reduced its capacity to prevent the disease but there were no grounds to conclude that scurvy was significant at the time of deserting the ships. There was no clear evidence of lead poisoning despite the relatively high level of lead exposure that was inevitable on ships at that time. There was no significant difference between the deaths of non-officer ranks on Franklin's ships and several of the search ships. The greater number of deaths of Franklin's officers was proposed to be more probably a result of non-medical factors such as accidents and injuries sustained while hunting and during exploration.
Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder
Authors: Jørgensen K. N. , Nerland S. , Norbom L. B. , Doan N. T. , Nesvåg R. , Mørch-Johnsen L. , Haukvik U. K. , Melle I. , Andreassen O. A. , Westlye L. T. , Agartz I. 
Published: April 2016

BackgroundSchizophrenia and bipolar disorder share genetic risk factors and one possible illness mechanism is abnormal myelination. T1-weighted magnetic resonance imaging (MRI) tissue intensities are sensitive to myelin content. Therefore, the contrast between grey- and white-matter intensities may reflect myelination along the cortical surface.MethodMRI images were obtained from patients with schizophrenia (n = 214), bipolar disorder (n = 185), and healthy controls (n = 278) and processed in FreeSurfer. The grey/white-matter contrast was computed at each vertex as the difference between average grey-matter intensity (sampled 0–60% into the cortical ribbon) and average white-matter intensity (sampled 0–1.5 mm into subcortical white matter), normalized by their average. Group differences were tested using linear models covarying for age and sex.ResultsPatients with schizophrenia had increased contrast compared to controls bilaterally in the post- and precentral gyri, the transverse temporal gyri and posterior insulae, and in parieto-occipital regions. In bipolar disorder, increased contrast was primarily localized in the left precentral gyrus. There were no significant differences between schizophrenia and bipolar disorder. Findings of increased contrast remained after adjusting for cortical area, thickness, and gyrification. We found no association with antipsychotic medication dose.ConclusionsIncreased contrast was found in highly myelinated low-level sensory and motor regions in schizophrenia, and to a lesser extent in bipolar disorder. We propose that these findings indicate reduced intracortical myelin. In accordance with the corollary discharge hypothesis, this could cause disinhibition of sensory input, resulting in distorted perceptual processing leading to the characteristic positive symptoms of schizophrenia.
Associations between the Brief Memory and Executive Test (BMET), Activities of Daily Living, and Quality of Life in Patients with Cerebral Small Vessel Disease
Authors: Hollocks Matthew J. , Brookes Rebecca , Morris Robin G. , Markus Hugh S. 
Published: April 2016

AbstractObjectives: In addition to neuropsychological difficulties, patients with cerebral small vessel disease (SVD) can have reduced activities of daily living and a poorer quality of life compared to healthy adults. The Brief Memory and Executive Test (BMET), is a cognitive screening tool designed to be sensitive to the neuropsychological profile of patients with SVD. While the BMET is sensitive to the cognitive consequences of SVD, it is unclear how well scores on this measure relate to functional outcomes. The aims of this study are to investigate the relationship between scores on the BMET and functional outcomes (activities of daily living and quality of life) in SVD, and to compare this with other commonly used cognitive screening tools. Methods: This study included 184 participants with SVD (mean age=63.2; SD=9.9) and 299 healthy controls (mean age=62.4; SD=13.8) who were tested using the BMET, Montreal Cognitive Assessment (MoCA), Mini-Mental State Examination (MMSE), Stroke Specific - Quality of Life Scale (SS-QoL), Geriatric Depression Scale (GDS), and measures of both instrumental activities of daily living (IADL) and basic activities of daily living (BADL). Results: After controlling for covariates the scores on the BMET, but not the MoCA or MMSE, were significantly related to poorer IADL and quality of life in the SVD group. In addition to the BMET scores, symptoms of depression were found to be significant associated with functional outcome. Conclusion: These results support the clinical utility of using of the BMET, in combination with a standardized depression questionnaire, during the early assessment of patients with SVD. (JINS, 2016, 22, 1–9)
Validity of WebCAAFE questionnaire for assessment of schoolchildren’s dietary compliance with Brazilian Food Guidelines
Authors: Kupek Emil , de Assis Maria Alice Altenburg , Bellisle France , Lobo Adriana Soares 
Published: April 2016

AbstractObjectiveTo estimate reporting bias of WebCAAFE, a web-based questionnaire for the assessment of food intake (recall of frequency of intake of thirty-two food items the day before) and physical activity in schoolchildren.DesignCross-sectional study. Self-reported food intake on WebCAAFE was compared with direct observation of school meals in five public schools. Additional data included school grade, sex, BMI, socio-economic status and access to Internet at home. Poisson regression was used to calculate the reporting bias (WebCAAFE v. direct observation) and the sample size necessary to detect a statistically significant difference between WebCAAFE reports and at least 75 % compliance with the recommendations for a healthy diet.SettingIntentional sample of five elementary public schools in Florianopolis, Brazil.SubjectsSchoolchildren (n 629) from 2nd to 5th grades.ResultsModerate bias magnitude was found for most food groups of interest. Frequency of consumption was not related to the bias. Sample sizes necessary to detect the compliance with dietary recommendations varied between four and seventy-four individuals for the different groups investigated.ConclusionsAfter adjusting for moderate bias, WebCAAFE may be used as a food questionnaire for evaluation of schoolchildren’s food compliance on a group level, even with a relatively small sample size.
Superconductivity below 20 K in heavily electron-doped surface layer of FeSe bulk crystal
Authors: Seo J. J. , Kim B. Y. , Kim B. S. , Jeong J. K. , Ok J. M. , Kim Jun Sung , Denlinger J. D. , Mo S. -K. , Kim C. , Kim Y. K. 
Published: April 2016

AbstractA superconducting transition temperature (Tc) as high as 100 K was recently discovered in one monolayer FeSe grown on SrTiO3. The discovery ignited efforts to identify the mechanism for the markedly enhanced Tc from its bulk value of 8 K. There are two main views about the origin of the Tc enhancement: interfacial effects and/or excess electrons with strong electron correlation. Here, we report the observation of superconductivity below 20 K in surface electron-doped bulk FeSe. The doped surface layer possesses all the key spectroscopic aspects of the monolayer FeSe on SrTiO3. Without interfacial effects, the surface layer state has a moderate Tc of 20 K with a smaller gap opening of 4.2 meV. Our results show that excess electrons with strong correlation cannot induce the maximum Tc, which in turn reveals the need for interfacial effects to achieve the highest Tc in one monolayer FeSe on SrTiO3.