bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability analysis of overload static pressure turntable based on fuzzy fault tree
Authors: Li Zekun , Chen Jie , Zhang Xiaogang , Ran Yan 
Published: October 2024

Abstract
To address issues such as frequent failures and high maintenance complexity in large overload static pressure turntables, this paper establishes a subsystem fault tree model for large overload static pressure turntables. It combines fuzzy mathematics theory to conduct a fault tree analysis, utilizing triangular fuzzy numbers to describe the failure probability of the turntable subsystem. This approach identifies the weak links that impact the reliability of the turntable system and devises reliability optimization solutions.
The response of the ocean carbon cycle to artificial upwelling, ocean iron fertilization and the combination of both
Authors: Jürchott M , Koeve W , Oschlies A 
Published: October 2024

Abstract
Artificial upwelling (AU) and ocean iron fertilization (OIF) both have been proposed as marine carbon dioxide removal methods to enhance ocean carbon uptake by stimulating the biological carbon pump. We simulate global and regional AU and OIF individually and the combination of both methods between the years 2025 and 2100 in ocean-atmosphere model experiments under the moderate RCP 4.5 CO2-emission pathway and show that the combination of globally applied AU + OIF yields the greatest ocean carbon uptake potential of +103 Pg C until year 2100. Regional OIF simulated by itself poleward of 45° North and South is responsible for +86.9 Pg C additional ocean carbon uptake. AU-only experiments do not significantly enhance ocean carbon uptake due to the lack of iron in the upwelled waters. We find no consistent relationship between enhanced cumulative export production and changes in the ocean carbon inventory attributable to the biological carbon pump, which makes export production a poor indicator for additional ocean carbon uptake. We identified a strong decrease in the global ocean nitrate inventory (−567 Tmol N) until year 2100 as a consequence of globally applied AU + OIF due to an interrupted balance between N2-fixation and denitrification.
Rediscovering Nostalgia
Authors: Macpherson Ben 
Published: October 2024

Abstract
This chapter considers the cultural politics of vocal imitation in bio-musical performances, exploring nostalgic vocality as the ‘counterpart’ to singing utopia. Using two complementary tendencies of ‘nostalgia’, selected examples from Jersey Boys (2005), Beautiful: The Carole King Musical (2014), and Tina: The Tina Turner Musical (2018) are analysed for what they reveal about nostalgia and its relationship to utopian ideals. These examples are listened to through three metaphorical audio filters: vocal drag (lipsynching), ventriloquism, and simulacrum. Drawing them together, the chapter introduces a third tendency of nostalgia, and a new term—‘simuloquism’—demonstrating its application as a means of understanding the relationship between ‘original’ voices of well-known singers, live voices in musical theatre performances, and complex experiences of the past, present, and future.
Punishment and the Value of Deserved Suffering
Authors: McKenna Michael 
Published: October 2024

Abstract
In this chapter, the conversational theory is extended to punishment, which is understood as distinct from blame. Among the differences between them, the intention of punishment is to harm, whereas this need not be so with blame. Regardless, punishment can also be treated as having a conversational character. Key to accounting for punishment on the conversational theory is that punishment engages an agent of a crime by seeking her experiencing a form of guilt that is a meaningful response from those who hold her to account. Punishments themselves are structured by supplying external conditions that can be taken as proper means of experiencing deserved guilt. The external conditions are suited for the desired internal response. Understood in this way, the forms and degree of punishment that a culpable person might deserve are far more limited than what is typically associated with retributivist theories.
Sitetack: a deep learning model that improves PTM prediction by using known PTMs
Authors: Gutierrez Clair S , Kassim Alia A , Gutierrez Benjamin D , Raines Ronald T 
Published: October 2024

Abstract

Motivation
Post-translational modifications (PTMs) increase the diversity of the proteome and are vital to organismal life and therapeutic strategies. Deep learning has been used to predict PTM locations. Still, limitations in datasets and their analyses compromise success.

Results
We evaluated the use of known PTM sites in prediction via sequence-based deep learning algorithms. For each PTM, known locations of that PTM were encoded as a separate amino acid before sequences were encoded via word embedding and passed into a convolutional neural network that predicts the probability of that PTM at a given site. Without labeling known PTMs, our models are on par with others. With labeling, however, we improved significantly upon extant models. Moreover, knowing PTM locations can increase the predictability of a different PTM. Our findings highlight the importance of PTMs for the installation of additional PTMs. We anticipate that including known PTM locations will enhance the performance of other proteomic machine learning algorithms.

Availability and implementation
Sitetack is available as a web tool at https://sitetack.net; the source code, representative datasets, instructions for local use, and select models are available at https://github.com/clair-gutierrez/sitetack.
HoloPatch: improving intracardiac patch fit through holographically modelled templates
Authors: Lippert Matthias , d’ Albenzio Gabriella , Suther Kathrine Rydén , Dumont Karl-Andreas , Palomar Rafael , Odland Hans Henrik , Elle Ole Jakob , Bendz Bjørn , Brun Henrik 
Published: October 2024

Abstract

Aims
Structural heart defects, including congenital ventricular septal defect closure or intracardiac rerouting, frequently require surgical reconstruction using hand-cut patch materials. Digitally modelled patch templates may improve patch fit and reduce outflow tract obstruction, residual defect risk, and conduction system damage. In this study, we benchmarked mixed-reality and a desktop application against a digitalized model of a real implanted patch.

Methods and results
Ten patients scheduled for the repair of various defects consented to prospective inclusion in the study. After surgery, a digital model of the implanted patch was created from the residual material. Five clinical experts created 10 digital patches, 1 per patient, both in mixed-reality and desktop application, for comparison with the reference measurements, including the digitalized model of the real patch used during the surgery. Subjective residual shunt risk prediction was performed using both modalities. Digital patches created in mixed-reality closely matched the surgical material, whereas those created using desktop applications were significantly smaller. Different evaluators showed varying preferences for the application of the residual shunt risk and area.

Conclusion
Digitally created patches can assist surgeons in preoperatively sizing of patch implants, potentially reducing post-operative complications.
Risk of venous thromboembolism in patients with congenital heart disease: a nationwide, register-based, case–control study
Authors: Cuszynska-Kruk Dagmara , Fedchenko Maria , Giang Kok Wai , Dellborg Mikael , Eriksson Peter , Hansson Per-Olof , Mandalenakis Zacharias 
Published: October 2024

Abstract

Aims
Patients with congenital heart disease (CHD) have an increased risk of developing acquired cardiovascular diseases. However, the risk of venous thromboembolism (VTE) in patients with CHD is unknown. We aimed to investigate the incidence and risk of VTE in patients with CHD compared with matched controls without CHD.

Methods and results
Data from Swedish health registers were used to identify all patients with CHD between 1970 and 2017 in Sweden. Each patient with CHD was matched with 10 controls from the Swedish Total Population Register. The primary outcome of the study was an event of VTE. Follow-up was from birth until VTE, death, or the end of the study (2017). Cox proportional hazard models were used to investigate the risk of VTE in patients with CHD and controls. A total of 67 814 patients with CHD and 583 709 matched controls were identified and included in the study. During a mean follow-up of 15.9 (SD ± 12.5) years, 554 (0.8%) patients with CHD and 1571 (0.3%) controls developed VTE. The risk of VTE was 3.3 [95% confidence interval [CI] 2.6–3.4) times higher in patients with CHD than in controls. Patients with conotruncal defects had the highest risk of VTE (hazard ratio 7.06, 95% CI 5.52–9.03).

Conclusion
In our nationwide study, we found that the risk of VTE in patients with CHD was more than three times higher than in matched controls. The highest risk of VTE was in patients with the most complex lesions. Further research is crucial to clarify the underlying risk factors and prevent VTE in patients with CHD.
Standardised and hierarchically classified heart failure and complementary disease monitoring outcome measures: european Unified Registries for heart Care evaluation and randomised trials (EuroHeart)
Authors: Bhatty Asad , Wilkinson Chris , Batra Gorav , Aktaa Suleman , Smith Adam B , Wahab Ali , Chappell Sam , Alfredsson Joakim , Erlinge David , Ferreira Jorge , Guðmundsdóttir Ingibjörg J , Hrafnkelsdóttir Þórdís Jóna , Ingimarsdóttir Inga Jóna , Irs Alar , Jánosi András , Járai Zoltán , Oliveira-Santos Manuel , Popescu Bogdan A , Vasko Peter , Vinereanu Dragos , Yap Jonathan , Bugiardini Raffaele , Cenko Edina , Nadarajah Ramesh , Sydes Matthew R , James Stefan , Maggioni Aldo P , Wallentin Lars , Casadei Barbara , Gale Chris P 
Published: October 2024

Abstract

Aims
The lack of standardised definitions for heart failure outcome measures limits the ability to reliably assess effectiveness of heart failure therapies. The European Unified Registries for Heart Care Evaluation and Randomised Trials (EuroHeart) aimed to produce a catalogue of internationally endorsed data definitions for heart failure outcome measures.

Methods
Following the EuroHeart methods for the development of cardiovascular data standards, a working group was formed of representatives from the European Society of Cardiology Heart Failure Association and other leading heart failure experts. A systematic review of observational and randomised clinical trials identified current outcome measures, which was supplemented by clinical practice guidelines and existing registries for contemporary definitions. A modified Delphi process was employed to gain consensus for variable inclusion and whether collection should be mandatory (Level 1) or optional (Level 2) within EuroHeart. In addition, a set of complementary outcome measures were identified by the Working Group as of scientific and clinical importance for longitudinal monitoring for people with heart failure.

Results
Five Level 1 and two Level 2 outcome measures were selected and defined, alongside five complementary monitoring outcomes for patients with heart failure.

Conclusion
We present a structured, hierarchical catalogue of internationally endorsed heart failure outcome measures. This will facilitate quality improvement, high quality observational research, registry-based trials, and post market surveillance of medical devices.
Taxonomic and functional partitioning of Chloroflexota populations under ferruginous conditions at and below the sediment-water interface
Authors: Vuillemin Aurèle , Ruiz-Blas Fatima , Yang Sizhong , Bartholomäus Alexander , Henny Cynthia , Kallmeyer Jens 
Published: October 2024

Abstract
The adaptation of the phylum Chloroflexota to various geochemical conditions is thought to have originated in primitive microbial ecosystems, involving hydrogenotrophic energy conservation under ferruginous anoxia. Oligotrophic deep waters displaying anoxic ferruginous conditions, such as those of Lake Towuti, and their sediments may thus constitute a preferential ecological niche for investigating metabolic versatility in modern Chloroflexota. Combining pore water geochemistry, cell counts, sulfate reduction rates, and 16S rRNA genes with in-depth analysis of metagenome-assembled genomes, we show that Chloroflexota benefit from cross-feeding on metabolites derived from canonical respiration chains and fermentation. Detailing their genetic contents, we provide molecular evidence that Anaerolineae have metabolic potential to use unconventional electron acceptors, different cytochromes, and multiple redox metalloproteins to cope with oxygen fluctuations, and thereby effectively colonizing the ferruginous sediment-water interface. In sediments, Dehalococcoidia evolved to be acetogens, scavenging fatty acids, haloacids, and aromatic acids, apparently bypassing specific steps in carbon assimilation pathways to perform energy-conserving secondary fermentations combined with CO2 fixation via the Wood–Ljungdahl pathway. Our study highlights the partitioning of Chloroflexota populations according to alternative electron acceptors and donors available at the sediment-water interface and below. Chloroflexota would have developed analogous primeval features due to oxygen fluctuations in ancient ferruginous ecosystems.
Socioeconomic Inequalities in Dementia Risk Among a Population-Based Cohort: Quantifying the Role of a Broad Combination of Lifestyle Factors
Authors: Zhao Ze , Yin Xiaoxv , Xu Minzhi 
Published: October 2024

Abstract

Objectives
The complex associations of socioeconomic status (SES) and lifestyle with dementia are unclear. Our objective was to examine whether a broad combination of lifestyle factors mediates the associations of SES with incident dementia and the extent of interaction or joint relations of lifestyles and SES with dementia.

Methods
A total of 274,871 participants from the UK Biobank were included. SES was assessed using the Townsend Deprivation Index. A lifestyle index was created based on smoking status, alcohol consumption, physical activity, social connections, sleep duration, diet, and sedentary behavior. Cox proportional hazards models were fitted. Mediation and interaction analyses were conducted to explore the relationship between lifestyles and SES in dementia.

Results
The hazard ratios (HRs) and 95% confidence intervals (CIs) for when participants with low SES were compared with participants with high SES were 1.32 (1.22–1.42) for all-cause dementia, 1.25 (1.11–1.40) for Alzheimer’s disease (AD), and 1.61 (1.37–1.90) for vascular dementia (VD). Lifestyles explained ≤7.8% of socioeconomic disparities in dementia. Unhealthy lifestyle categories were associated with a higher risk of dementia and its subtypes across all SES levels. The HRs (95% CIs) for all-cause dementia, AD, and VD comparing participants with low SES and the least healthy lifestyle versus those with high SES and the healthiest lifestyle were 1.82 (1.56–2.11), 1.51 (1.20–1.90), and 2.56 (1.81–3.61), respectively.

Discussion
Adhering to a healthy lifestyle may prevent dementia across all socioeconomic groups, but socioeconomic inequalities in dementia cannot be fully addressed by promoting healthy lifestyles alone. The social determinants of dementia need to be better addressed.
Filling the Accountability Gap: Misleading Conduct Law in Business and Human Rights
Authors: Hansen Lee , Pillay Renginee G 
Published: October 2024

Abstract
This article examines the use of misleading conduct law to challenge false or deceptive business claims about their human rights practices and impacts. It does so in the context of recent developments in the field of business and human rights including the introduction of non-financial reporting, disclosure and human rights due diligence that have seen an increase in business communications about their human rights impacts. The article uses the Protect, Respect and Remedy framework of the United Nations Guiding Principles on Business and Human Rights to analyse the EU Directive on Unfair Commercial Practices (2005/29) and the Australian Consumer Law. Each prohibit misleading conduct by business. The article argues that, to differing extents, these legislations partially address the accountability gap that has emerged in the context of corporate human rights claims and practices.
Supply chain network equilibrium with outsourcing for fresh agricultural products under stochastic demands
Authors: Chen Pin-bo , Lin Gui-hua , Xu Weina , Zhu Xide 
Published: October 2024

Abstract
Accepted by: M. Zied Babai
This paper examines a supply chain network focusing on the distribution of fresh agricultural products, incorporating outsourcing and stochastic demands considerations. Initially, we establish a generalized Nash equilibrium model with stochastic demands among fresh produce firms. Subsequently, we transform this model into a mixed complementarity system using the Karush–Kuhn–Tucker conditions. Utilizing the Fischer–Burmeister function, we further convert the mixed complementarity system into a set of nonlinear equations, amenable to solution via GAMS software. We conduct numerical experiments and perform sensitivity analysis on key parameters. Our findings suggest that higher subsidy rates incentivize firms towards production outsourcing, particularly benefiting low-income farmers, thereby potentially increasing profits. Moreover, market fluctuations play a pivotal role in ensuring the stability and profitability of firms, with moderate fluctuations presenting opportunities for fresh enterprises to adapt, innovate and capitalize on evolving market conditions. These results offer valuable insights for effective management of fresh produce supply chains.
Asymptotically exact formulas for channel flows over liquid-infused surfaces
Authors: Rodriguez-Broadbent Henry , Miyoshi Hiroyuki , Crowdy Darren G 
Published: October 2024

Abstract
Analytical formulas are derived describing channel flows over liquid-infused surfaces. The formulas are explicit, asymptotically exact and readily evaluated; no numerical scheme beyond simple quadrature is needed to calculate the flows. The formulas are obtained using a three-stage asymptotic analysis under the assumptions that an array of aligned finite-length grooves on the lower wall of a channel are (i) slender, (ii) well separated from the upper channel wall and (iii) well separated from each other. Despite these apparently limiting assumptions it is found, by comparison with full numerical simulations, that the formulas give excellent approximations to the flow across a much broader range of operating conditions. Useful formulas for the hydrodynamic slip lengths of the liquid-infused surfaces are reported and tested against both numerical simulations and other approximate formulas appearing in the literature. The formulas are also expected to be useful in assessing the possibility of so-called shear-induced failure of liquid-infused surfaces.
A novel variable neighborhood descent algorithm for service restoration in radial electrical distribution networks
Authors: Puerta Gabriel F , Macedo Leonardo H , Soares João , Romero Rubén 
Published: October 2024

Abstract
This paper presents a variable neighborhood descent algorithm for the service restoration problem (SRP) in electrical distribution systems. The restoration problem appears when a permanent fault occurs in the system. The fault must be localized and isolated from the rest of the system. As a consequence of the isolation, the downstream area is de-energized and requires restoration. The variable neighborhood descent algorithm features its ability to solve the SRP for radial distribution systems and introduces a strategy that helps to deal with the system’s radiality. Tests are performed using a 53-node test system. The results show that the proposed algorithm can efficiently solve the SRP in a distribution system, and as a deterministic algorithm, the results can be used to help nondeterministic algorithms.
Retrospective Observational Analysis of Computed Tomography Scans of Trauma Patients in Overseas Operations (SCANOPEX Study)
Authors: Ikni Laura , Valbousquet Laura , Dufour-Gaume Frederique , Potet Julien 
Published: October 2024

ABSTRACT

Introduction
High-intensity conflicts are on Europe’s doorstep. The French expertise in the medical management of frontline casualties in overseas operations is well established. However, in the management of severe trauma, we lack data on the injuries identified by body scanners in the field. Understanding the associations between injury mechanisms and radiological lesions would enable us to anticipate medical and surgical management. To study this possible link, we collected and interpreted scanogaphic data and analyzed them according to lesion mechanisms, following the algorithm MARCH used to implement the concept of Damage Control Resuscitation, which includes life-saving measures to ensure that the wounded reach medical-surgical facilities alive.

Materials and methods
This retrospective monocentric study collected data from body scanners performed in overseas operations between June 2011 and September 2023. Inclusion criteria were to be French military personnel and to have undergone a whole-body scanner in a theater of overseas operations. Exclusion criteria were to have died before the scan, to be foreign, non-military and a minor. Of 164 available files, 96 were eligible, 1 patient declared aged 70 years was excluded, and 95 files were retained.

Results
In our population, 18% of injured patients had a spinal fracture. Compared with road traffic accident casualties, improvised explosive device casualties were the most severely injured patients arriving alive at computed tomography, with a relative risk of Injury Severity Score &gt; 8 of 2.29 [1.09-4.80] (P = .019). Improvised explosive device casualties had a relative risk of airway injuries of 2.57 [1.03-6.39] (P = .030), injuries leading to functional impairment of 3.21 [1.17-8.82] (P =.013), injuries leading to infection of 2.14 [1.21-3.76] (P = .0045), and injuries leading to shock of 3.21 [0.96-10.70] (P = .039). Deep metal splinters were only found in the improvised explosive device group.

Conclusion
Preparing the medical corps to deal with war casualties is fundamental. Our study shows that it is essential to consider the mechanism of injury to understand the casualty better and predict potential injuries. In addition, the study of postmortem scans could greatly help analyze potentially avoidable deaths.