bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thalamic and Entorhinal Network Activity Differently Modulates the Functional Development of Prefrontal–Hippocampal Interactions
Authors: Hartung Henrike , Brockmann Marco D. , Pöschel Beatrice , De Feo Vito , Hanganu-Opatz Ileana L. 
Published: March 2016

Precise information flow during mnemonic and executive tasks requires the coactivation of adult prefrontal and hippocampal networks in oscillatory rhythms. This interplay emerges early in life, most likely as an anticipatory template of later cognitive performance. At neonatal age, hippocampal theta bursts drive the generation of prefrontal theta-gamma oscillations. In the absence of direct reciprocal interactions, the question arises of which feedback mechanisms control the early entrainment of prefrontal–hippocampal networks. Here, we demonstrate that prefrontal–hippocampal activity couples with discontinuous theta oscillations and neuronal firing in both lateral entorhinal cortex and ventral midline thalamic nuclei of neonatal rats. However, these two brain areas have different contributions to the neonatal long-range communication. The entorhinal cortex mainly modulates the hippocampal activity via direct axonal projections. In contrast, thalamic theta bursts are controlled by the prefrontal cortex via mutual projections and contribute to hippocampal activity. Thus, the neonatal prefrontal cortex modulates the level of hippocampal activation by directed interactions with the ventral midline thalamus. Similar to the adult task-related communication, theta-band activity ensures the feedback control of long-range coupling in the developing brain.SIGNIFICANCE STATEMENTMemories are encoded by finely tuned interactions within large-scale neuronal networks. This cognitive performance is not inherited, but progressively matures in relationship with the establishment of long-range coupling in the immature brain. The hippocampus initiates and unidirectionally drives the oscillatory entrainment of neonatal prefrontal cortex, yet feedback interactions that precisely control this early communication are still unresolved. Here, we identified distinct roles of entorhinal cortex and ventral midline thalamus for the functional development of prefrontal–hippocampal interactions. While entorhinal oscillations modulate the hippocampal activity by timing the neuronal firing via monosynaptic afferents, thalamic nuclei act as a relay station routing prefrontal activation back to hippocampus. Understanding the mechanisms of network maturation represents the prerequisite for assessing circuit dysfunction in neurodevelopmental disorders.
Molecular cues to the anti-implantation effect of nano-puerarin in rats
Authors: Saraswat Ghungroo , Guha Rajdeep , Mondal Kalyani , Saha Piyali , Banerjee Sayani , Chakraborty Prarthana , Konar Aditya , Kabir Syed N 
Published: March 2016

AbstractPuerarin, a selective oestrogen receptor modulator, intercepts implantation in rats, albeit at unacceptably higher doses. We developed poly lactic-co-glycolic acid-encapsulated nano-puerarin (PN) and mapped the molecular pathway underlying its anti-implantation effects. Smooth-surfaced and spherical PN having a mean diameter of ∼147nm was obtained with good yield, efficient encapsulation, and optimum drug loading. In culture, PN slowly and steadily released puerarin, which was readily taken up by the decidual cells. PN exerted a dose-dependent anti-implantation effect. As marked by attenuated expression of stromal cell desmin, alkaline phosphatase, IGFBP1, and decidual prolactin-related protein, the anti-implantation effect of PN seemed secondary to compromised decidualization. Usingin vivo(pregnant and pseudopregnant rats) andin vitro(endometrial stromal cell culture) treatment models, we document that PN enforced inhibition of uterine expression ofHbegfandHoxa10and their downstream signalling molecules, Cyclin D3 (CCND3)/CDK4. PN also efficiently ablated theIhh-Nr2f2-Bmp2signalling pathway and invited the loss of uterine potential for decidualization. There was a dose-dependent up-regulation of RHOA and its effector protein kinase, ROCK1, leading to the promotion of MLC phosphorylation and actin–myosin interaction. PN also down-regulated the stromal cell activation of ERK½ and expression of MMP9. These effects acting together stabilized the stroma and inhibited the stromal cell migration. Central to this array of events was the adversely altered endometrial expression of oestrogen receptor subtypes and repression of progesterone receptor that indulged endless proliferation of luminal epithelia and distorted the precisely choreographed stroma–epithelia crosstalk. Thus, PN dismantles the endometrial bed preparation and prevents implantation.
MUS VIENIJA ALUS IR TELEVIZIJA: ŽINIASKLAIDOS AUDITORIJOS (NE)FRAGMENTACIJA 2012 METŲ SEIMO RINKIMŲ KAMPANIJOS METU
Authors: Nevinskaitė Laima 
Published: March 2016

The aim of the article is to analyse the extent of media audience fragmentation in Lithuania during the 2012 Parliament election campaign and to define which media channels are best able to unify the audience. Increasing fragmentation of media audience raises concerns about its possible effects on democracy. The concerns are that different fragments of the audience will not hear each other and will not talk to each other, which poses a threat to the unity of political community and hampers a constructive discussion on the common matters and consensus based common decisions. However, audience fragmentation is still under-researched empirically.The article uses data from a representative survey conducted after the 2012 Parliamentary elections and asks questions on the pre-election period. Methodologically, the analysis is based on the analysis of audience duplication of different media outlets, as well as network analysis to visualise the duplication of audiences. The article analyses data on the use of different news-oriented media outlets with the largest audience share from all media branches (television, radio, daily newspapers, and internet portals) and calculations of their audience duplication.Although there is no firm point of comparison to assess the extent of fragmentation (e.g. historical data), the data show a considerable overlap of media audiences. Most probably, the fragmentation would be larger in the periphery of the media system, but the analysis of the main media shows a considerable overlap. Therefore, the main conclusion is made that the Lithuanian media audience is not (yet) fragmented.The media that unites the biggest share of the audience is television. Although it is positive that it is still able to connect different fragments, in terms of content it is negative that during the pre-election period it had comparatively little amount of information on election campaign, parties and candidates. However, a very popular media outlet competing with television was the biggest internet news portal, which had a huge amount of information on elections.The article also includes analysis of agenda fragmentation in the audience which revealed the tendency of internet users to have a more fragmented agenda than the part of the audience that doesn’t use the internet. However, in comparison to similar Norwegian data on agenda fragmentation, the agenda of the Lithuanian audience could not be regarded as fragmented.In the future, the analysis of audience fragmentation will be dependent on the collection of comparable data, since it would provide data for comparison and assessing the trends of fragmentation in time. These data would also help to solve some methodological issues that are also discussed in the article, like choice of criteria for assessment and having a point of comparison.
LOJALUMO STRUKTŪROS ĮTAKA LIETUVOS VIEŠOJO SEKTORIAUS POLITIZACIJAI
Authors: Kazakevičius Giedrius 
Published: March 2016

SummaryThis article deals with politicisation of the public sector in Lithuania in the context of ensuring loyalty of high public officials to the politics of the Government of the day. The theoretical framework of Public Service Bargains (PSBs) was used in order to analyse historical changes and contemporary perception of loyalty among politicians and high public officials.The analysis of available historical researches does not allow identifying precisely a clear picture of the loyalty bargain in the public sector of the interwar Lithuania. But the lack of clear legal framework, some elements of the tsarist Russia public administration tradition and no evidence on the intended attempt to create loyalty to the state and the law don’t allow regarding historical Lithuanian interwar tradition as a hierarchical loyalty bargain. Post-war Soviet type administration tradition in Lithuania was analysed taking into account the researches of central Soviet administration tradition as well as studies of the Soviet Lithuania administration. A close look at the dual type Soviet administration provides evidence on the domination of egalitarian with some individualistic elements loyalty bargain type among the ruling elite. This type of loyalty bargain was secured by a personal loyalty network based on formal and informal ties. An analysis of changes in the legislative framework after re-establishing independence was used to identify the attempts to redefine loyalty bargain in transition period. The integration to the EU was a factor that was used by the administrative elite of Lithuania to secure a hierarchical loyalty bargain in a formal and legalistic way without reaching a common understanding with politicians. This hierarchical loyalty bargain is not based on historical administrative or cultural tradition. An analysis of biographies of the heads of the policy making institutions, statements of politicians as well as courts’ decisions regarding the removal from office provides a mixed picture regarding the praxis of loyalty bargain in the Lithuanian public sector. There is some evidence that politicians prefer egalitarian loyalty bargain and do not recognise formal hierarchical loyalty setting. The hierarchical loyalty bargain is tolerated by politicians only with judges and in some cases with the heads of the regulatory agencies. On the other hand, most of the heads of the policy making institutions are making attempts to consolidate the hierarchical loyalty bargain through legal means. This situation could be regarded as cheating on loyalty bargain from both sides that provoke politicians to search for new ways in achieving the loyalty of high public officials to the politics of the incumbent government and exercise politicisation practices for that purpose
Mood, motives, and money: An examination of factors that differentiate online and non-online young adult gamblers
Authors: Goldstein Abby L. , Vilhena-Churchill Natalie , Stewart Sherry H. , Hoaken Peter N. S. , Flett Gordon L. 
Published: March 2016

Background and aims
To date, there is a lack of research on psychological factors associated with young adult online gambling. The current study examined differences between young adult online and non-online gamblers, using information gathered at baseline and over 30 days during which participants reported on their moods, gambling behaviors, and reasons for initiating and discontinuing gambling.

Methods
Participants were 108 young adult regular gamblers (i.e., gambling four or more times in the past month) who participated in a 30-day daily diary study.

Results
Male gender, baseline coping motives for gambling and negative affect averaged across the 30 days emerged as significant correlates of online gambling, over and above other background variables. Online gamblers also scored higher on a baseline measure of pathological gambling. Over the 30 days of self-monitoring, online gamblers spent more time gambling, and won more money gambling, whereas non-online gamblers consumed more alcohol while gambling. Online gambling was more often initiated to make money, because of boredom and to demonstrate skills, whereas non-online gambling was more often initiated for social reasons and for excitement. Online gambling was more often discontinued because of boredom, fatigue or distress, whereas non-online gambling was discontinued because friends stopped gambling or mood was improved.

Discussion and conclusions
This study provides preliminary evidence that coping strategies may be particularly important to reduce risks for online gamblers, whereas strategies for non-online gamblers should focus on the social aspects of gambling.
Book Reviews
Authors: Virág Márta , Tamás Kollár 
Published: March 2016

Michael S. Gazzaniga, Richard B. Ivry and George R. Mangun Cognitive neuroscience: The biology of the mind (International student edition) (4th ed.)
Trevor W. Robbins, Barry J. Everitt and David J. Nutt The neurobiology of addiction Oxford, UK: Oxford University Press, 2010, 318 pp. ISBN: 978-0-1995-6215-2
Y Juca Pirama, estruturação
Authors: Pandolfo Maria do Carmo , Ranauro Hilma , Casa Nova Vera Lúcia De Carvalho , Garcia Armando Edson 
Published: March 2016

Resumo: Análise das estruturas míticas de I Juca Pirama de G. Dias, salientando a arnbiguidade do heroi mítico e o paradoxo romântico nele contido.Résumé: Analyse des structures mythiques du texte I Juca-Pirama de Gonçalves Dias, en soulignant l'ambiguité du héros mythique et le paradoxe romantique y inscrit.
A perfeição mortal
Authors: Paulino Maria das Graças Rodrigues 
Published: March 2016

Resumo: A partir de um conto de Julio Cortázar, questiona-se a busca da perfeição estética na medida em que esta se torna instrumento de uma absolutização fantasmática da identidade.Résumé: A partir d'un conte de Julio Cortázar nous mettons en question ici la quête de la perfection esthétique dans la mesure ou celle-ci devient instrument d'un absolu fantasmatique de l'identité.
COMPETÊNCIAS GERENCIAIS EVIDENCIADAS E DESEJADAS DOS INTEGRANTES DO FÓRUM DE GESTÃO DE PESSOAS DA REDE FEDERAL DE EDUCAÇÃO PROFISSIONAL, CIENTÍFICA E TECNOLÓGICA
Authors: P.T. de Mello Simone , De Melo Pedro Antônio , Teixeira de Mello Filho Raul 
Published: March 2016

<p>A Política para o Desenvolvimento de Pessoal da administração pública federal via Decreto Federal (DF) n. 5.707/06 tem como uma de suas diretrizes a promoção da capacitação gerencial do servidor e sua qualificação para o exercício de atividades de direção e assessoramento, tendo como um dos instrumentos dessa política a gestão por competências. Com este estudo se objetivou identificar os desafios cotidianos, os entendimentos sobre gestão por competências, assim como mapear as competências gerenciais dos integrantes do Fórum de Gestão de Pessoas (Forgep) da Rede Federal de Educação Profissional, Científica e Tecnológica (Rfept), no caso, gestores de pessoas que participam de encontros regulares do citado Fórum. A metodologia é de essência qualitativa. Utilizou-se o software <em>limesurvey </em>para a coleta de dados e, para a análise destes, valeu-se da análise de conteúdo (BARDIN, 2009; VERGARA, 2006). Os resultados revelam os desafios mais frequentes dos gestores: excesso de trabalho e carência de servidores. Seus entendimentos sobre gestão por competências são vagos se comparados à literatura pertinente. Suas competências mais evidenciadas são: comunicação, liderança e gestão de conflitos, e as desejadas por eles são: organização do tempo, comunicação, motivação e liderança. Espera-se que a pesquisa contribua para ações de governo mais efetivas. É essencial conceber o gerenciamento de pessoas como área estratégica das instituições, o que implica capacitação e qualificação de gestores de pessoas, sujeitos significativos no desenvolvimento da gestão por competências na prática.<em></em></p><p>Palavras-chave: Competências gerenciais. Mapeamento de competências. Gestão de pessoas. Administração pública</p>
‘Independence is we nature…’: Growing up in a postcolonial Caribbean country
Authors: DePass Cecille 
Published: March 2016

By incorporating oral and narrative history from personal and family stories, this article draws on
Caribbean idioms and cultural characteristics as a form of ‘decolonizing one’s mind’ (Pieterse
and Parekh, 1995; Lamming, 1960; Ngugi wa Thiong’o, 1986). Divided into three related parts,
Part One portrays the Eurofeminist adage that the personal is political. Family history and
memory become the focus for retelling stories of the severe restrictions for education and
mobility in a former Crown colony. Part Two highlights a few personal non-formal learning
activities which acted as sites for learning compliance and resistance in playful and nonthreatening
ways. Part Three moves to the world of the large working class population, a
historical site of resistance to oppression. By concentrating on women’s lives, it reveals some of
the social tensions between women and men and, as important, illustrates the efforts of women
through a collective to achieve self-sufficiency for themselves and their families.
PEMBANGUNAN GIANT SEA WALL: BERMANFAATKAH BAGI MASYARAKAT PERIKANAN ?
Authors: Zulham Armen 
Published: March 2016

<p><strong>RINGKASAN</strong><br /><br />Pembangunan Giant Sea Wall (GSW) di Teluk Jakarta merupakan program lintas kementerian, yang dirancang untuk mendukung perekonomian dan mengendalikan banjir di Jakarta. Permasalahan GSW tersebut, tidak hanya terkait dengan aspek teknis kontruksi dan lingkungan, tetapi terkait juga dengan aspek sosial ekonomi tentang investasi dan pertumbuhan usaha perikanan. Saat ini, pada kawasan itu terdapat berbagai investasi dan lapangan usaha perikanan. Data statistik, menunjukkan peran lapangan usaha perikanan dalam perekonomian Jakarta Utara menurun dari 0,10% pada tahun 2006 menjadi 0,08% pada tahun 2012. Penurunan peran ini, bukan berarti lapangan usaha perikanan ini tidak penting. Selama ini, lapangan usaha perikanan di kawasan itu merupakan sabuk pengaman yang mampu menyediakan lapangan kerja untuk 30 ribu orang dari berbagai kelompok masyarakat di Teluk Jakarta. Invasi investasi sekitar Rp. 600 triliun untuk pembangunan GSW sampai tahun 2030, merupakan instrumen fiskal penting yang dapat mempercepat tumbuhnya perekonomian di kawasan tersebut. Instrumen ini menurut beberapa pihak, dapat menjadi stimulus pembangunan, namun pihak lain menganggap, dapat menjadi “jebakan fiskal untuk sektor perikanan”. Tulisan ini melihat, pembangunan GSW tersebut membuka peluang usaha baru bagi masyarakat perikanan. Namun, untuk memanfaatkan peluang itu diperlukan berbagai kebijakan yang inovatif.</p><p><br />Kata kunci : giant sea wall, demografi, nelayan, pembudidaya, pengolah <br /><br /></p>
BISAKAH TRANSPLANTASI KARANG PERBAIKI EKOSISTEM TERUMBU KARANG ?
Authors: Subhan Beginer , Madduppa Hawis , Arafat Dondy , Soedharma Dedi 
Published: March 2016

<p>RINGKASAN</p><p>Transplantasi karang merupakan teknik perbanyakan koloni karang dengan memanfaatkan reproduksi aseksual karang secara fagmentasi. Berbagai kalangan dapat terlibat dalam mengusahakan dan melakukan rehabilitasi karang dengan metode ini. Namun saat ini metode yang digunakan masih ada yang mengadopsi metode untuk perdagangan karang hias bukan untuk rehabilitasi. Metode dengan beton dan pengontrolan terhadap alga salah satu kunci keberhasilan dalam transplantasi karang. Pencarian bibit-bibit karang yang unggul yang kuat terhadap alga dan penyakit menjadi solusi penting dalam peningkatan keberhasilan transplantasi karang.</p><p>Kata kunci: transplantasi karang, metode beton, penyakit karang, alga <br /><br /></p>
How Can Integrated Operation Contribute to Improve the Efficiency on the Norwegian Continental Shelf?
Authors: Kaland T. , Nordtvedt J. E. , Seim O. 
Published: March 2016

Abstract
This paper will address how Integrated Operations (IO) can assist the oil and gas sector in Norway with implementing more cost effective operations. The paper will initially analyze the implementation of Integrated Operation activities within oil and gas operators and service companies on the Norwegian Continental Shelf (NCS) over the past 15 years. The industry at the NCS has in this period seen a huge growth, and significant value from implementation of IO initiatives has been harvested. Also, a series of "external events" has occurred partly supporting and partly challenging implementation of Integrated Operations. For example, the two largest operators merged in that period, the oil prize raised significantly initially, but dropped back last year. In addition, the efficiency of use of personnel has dropped, the drilling efficiency has gone down significantly, and the overall cost of operating has increased significantly. As a consequence, when the oil priced then dropped in 2014, the industry was quite vulnerable. With this back-drop, this paper discusses how IO can contribute to improve the efficiency on the NCS. We are particularly focused on improvements to the way we work, the relationship between the operator and contractor and on how we are utilizing personnel resources effectively. Key questions are how we can improve on the way of working and decision-making by having much more readily available all relevant information and improving situational awareness and cross-discipline collaboration when making decisions, and how cross-training and new contract structures can reduce the number of people offshore.
Impact of Co-Infections in Lyme Disease
Authors: Stinco Giuseppe , Bergamo Serena 
Published: March 2016

Lyme disease is one of the most frequent tick-borne diseases worldwide, it can be multi-systemic and insidious, in particular when it shows a chronic course.In recent years co-infections represent an emerging issue in Lyme disease spectrum because in addition toBorrelia burgdorferi slmany other potential pathogens may be transmitted by hard ticks Ixodes species. The main co-infections found in Lyme disease described in this review are represented byAnaplasma phagocytophilum, Babesia species, Bartonella species, Rickettsiae species and tick-borne encephalitis virus. For each single co-infecting micro-organism, clinical features, diagnostic issues and therapeutical approaches are discussed.Co-infections represent an emerging problem because they might exacerbate Lyme disease clinical features, they can also mimic Lyme borreliosis sharing common manifestations, and eventually they can change the course of the disease itself.The presence of one or more co-infecting agent during the course of Lyme disease may represent an issue especially in endemic areas for tick-borne diseases and in people occupationally exposed.The aim of this review is to summarize the more important co-infections in patients with Lyme disease and to discuss their importance in the disease process.