bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of factors associated with smoking cessation at diagnosis or during follow‐up of Crohn's disease
Authors: Song Eun Mi , Kim Gwang‐Un , Seo Myeongsook , Hwang Sung Wook , Park Sang Hyoung , Kwon Eunja , Lee Ho‐Su , Yang Dong‐Hoon , Kim Kyung‐Jo , Ye Byong Duk , Byeon Jeong‐Sik , Myung Seung‐Jae , Yang Suk‐Kyun 
Published: May 2017

AbstractBackground and AimSmoking cessation is known to improve the course of Crohn's disease (CD). However, the factors associated with smoking cessation after CD diagnosis have not been well established.MethodsClinical characteristics and change in smoking status were evaluated in 445 current smokers at the time of CD diagnosis. Patients were classified into three subgroups based on their final smoking status and time of smoking cessation: non‐quitters, quitters at diagnosis, and quitters during follow‐up.ResultsThe overall smoking cessation rate was 55.7% (248 of 445 patients). The diagnosis of CD was the main reason for quitting (41.5%, 103 of 248 patients). Smoking cessation at the time of CD diagnosis was associated with intestinal resection within 3 months from CD diagnosis (odds ratio [OR] 2.355, 95% confidence interval [CI] 1.348–4.116, P = 0.003), light smoking (OR 2.041, 95% CI 1.157–3.602, P = 0.014), and initiation of smoking before 18 years of age (OR 0.570, 95% CI 0.327–0.994, P = 0.047). Light smoking (OR 1.762, 95% CI 1.019–3.144, P = 0.043) and initiation of smoking before 18 years (OR 0.588, 95% CI 0.381–0.908, P = 0.017) were also associated with overall smoking cessation.ConclusionQuitters after CD diagnosis, including quitters at diagnosis and quitters during follow‐up, had features distinct from those of non‐quitters. Given the motivation at CD diagnosis, a detailed history of smoking habits should be taken and all current smokers should be encouraged to quit smoking at the time of CD diagnosis.
Oral Health and Dental Care in Older Asian Americans in Central Texas
Authors: Jang Yuri , Yoon Hyunwoo , Park Nan Sook , Chiriboga David A. 
Published: May 2017

ObjectivesTo examine factors associated with dental health insurance, self‐rated oral health, and use of preventive dental care services in older Asian Americans.DesignCross‐sectional survey.SettingThe Asian American Quality of Life Survey was conducted with 2,614 Asian Americans living in central Texas using questionnaires available in English and six Asian languages.ParticipantsAsian American Quality of Life Survey participants aged 60 and older (N = 533; mean age = 69.4 ± 6.9).MeasurementsParticipants were asked whether they had insurance that covered the cost of any dental visit, how they would rate their overall oral health status, and whether they had visited a dental clinic for a routine examination in the past 12 months. Information was also collected on sociodemographic and immigration‐related variables.ResultsMore than 61% of the sample had no dental health insurance, 45% reported that their oral health was fair or poor, and 44% had not used preventive dental care services. A series of logistic regression analyses identified factors posing a significant risk to oral health and dental care. For example, those with limited English proficiency were 3.5 times as likely to lack dental health insurance and 3.2 times as likely to rate their oral health as fair or poor. The odds of not using preventive dental care services were 6.4 times as great in those without dental health insurance.ConclusionThe overall findings call attention to efforts to promote oral health and dental care in older Asian Americans.
Research Priorities to Advance the Health and Health Care of Older Adults with Multiple Chronic Conditions
Authors: Tisminetzky Mayra , Bayliss Elizabeth A. , Magaziner Jay S. , Allore Heather G. , Anzuoni Kathryn , Boyd Cynthia M. , Gill Thomas M. , Go Alan S. , Greenspan Susan L. , Hanson Leah R. , Hornbrook Mark C. , Kitzman Dalane W. , Larson Eric B. , Naylor Mary D. , Shirley Benjamin E. , Tai‐Seale Ming , Teri Linda , Tinetti Mary E. , Whitson Heather E. , Gurwitz Jerry H. 
Published: May 2017

ObjectivesTo prioritize research topics relevant to the care of the growing population of older adults with multiple chronic conditions (MCCs).DesignSurvey of experts in MCC practice, research, and policy. Topics were derived from white papers, funding announcements, or funded research projects relating to older adults with MCCs.SettingSurvey conducted through the Health Care Systems Research Network (HCSRN) and Claude D. Pepper Older Americans Independence Centers (OAICs) Advancing Geriatrics Infrastructure and Network Growth Initiative, a joint endeavor of the HCSRN and OAICs.ParticipantsIndividuals affiliated with the HCSRN or OAICs and national MCC experts, including individuals affiliated with funding agencies having MCC‐related grant portfolios.MeasurementsA “top box” methodology was used, counting the number of respondents selecting the top response on a 5‐point Likert scale and dividing by the total number of responses to calculate a top box percentage for each of 37 topics.ResultsThe highest‐ranked research topics relevant to the health and healthcare of older adults with MCCs were health‐related quality of life in older adults with MCCs; development of assessment tools (to assess, e.g., symptom burden, quality of life, function); interactions between medications, disease processes, and health outcomes; disability; implementation of novel (and scalable) models of care; association between clusters of chronic conditions and clinical, financial, and social outcomes; role of caregivers; symptom burden; shared decision‐making to enhance care planning; and tools to improve clinical decision‐making.ConclusionStudy findings serve to inform the development of a comprehensive research agenda to address the challenges relating to the care of this “high‐need, high‐cost” population and the healthcare delivery systems responsible for serving it.
Digital dissection of the model organism Xenopus laevis using contrast‐enhanced computed tomography
Authors: Porro Laura B. , Richards Christopher T. 
Published: May 2017

AbstractThe African clawed frog, Xenopus laevis, is one of the most widely used model organisms in biological research. However, the most recent anatomical description of X. laevis was produced nearly a century ago. Compared with other anurans, pipid frogs – including X. laevis – exhibit numerous unusual morphological features; thus, anatomical descriptions of more ‘typical’ frogs do not detail many aspects of X. laevis skeletal and soft‐tissue morphology. The relatively new method of using iodine‐based agents to stain soft tissues prior to high‐resolution X‐ray imaging has several advantages over gross dissection, such as enabling dissection of very small and fragile specimens, and preserving the three‐dimensional topology of anatomical structures. Here, we use contrast‐enhanced computed tomography to produce a high‐resolution three‐dimensional digital dissection of a post‐metamorphic X. laevis to successfully visualize: skeletal and muscular anatomy; the nervous, respiratory, digestive, excretory and reproductive systems; and the major sense organs. Our digital dissection updates and supplements previous anatomical descriptions of this key model organism, and we present the three‐dimensional data as interactive portable document format (PDF) files that are easily accessible and freely available for research and educational purposes. The data presented here hold enormous potential for applications beyond descriptive purposes, particularly for biological researchers using this taxon as a model organism, comparative anatomy and biomechanical modelling.
Anatomical relationship of maxillary posterior teeth with the sinus floor and buccal cortex
Authors: Jang J. K. , Kwak S. W. , Ha J. H. , Kim H. C. 
Published: May 2017

SummaryThis study aimed to evaluate the possibility of root fenestration or oroantral communication by evaluating the distance from root apex to the sinus floor and buccal cortex in maxillary posterior teeth using cone‐beam computed tomography (CBCT) images. The study included 2182 roots of the maxillary posterior teeth from 219 patients after reviewing CBCT images of 462 patients according to the location of roots by two endodontists. The distances from each root apex to the maxillary sinus floor and buccal and palatal cortices were evaluated according to sex and age, and the mean values were compared by one‐way analysis of variance and Mann–Whitney U‐test. The distance between root apex and maxillary sinus floor was the greatest in maxillary first premolars and shortest in the mesio‐buccal roots of maxillary second molars. The distances from root apex to the buccal and palatal cortical bones were significantly greater in male patients than those in female patients (P < 0·05). The palatal roots of maxillary first molars exhibited the highest incidence as well as the greatest mean length (1·96 mm) of protrusion into the maxillary sinus. The distance from root apex to the sinus floor was found to increase with age, except in case of maxillary second premolars. Understanding the relationship of maxillary posterior teeth with the sinus floor and buccal cortex could provide clinicians valuable information to help reduce iatrogenic damage.
First‐night effect on cardiac autonomic function in different female reproductive states
Authors: Virtanen Irina , Kalleinen Nea , Urrila Anna S. , Polo‐Kantola Päivi 
Published: May 2017

SummaryDecreases in heart rate variability, a marker of autonomic nervous system function, are associated with increased cardiovascular mortality. Heart rate variability increases in non‐rapid eye movement sleep, peaking in slow‐wave sleep. Therefore, decreasing the amount of deep sleep, for example, by introducing patients to a sleep laboratory environment, could decrease heart rate variability, increasing cardiovascular risk. We studied four groups of women with no previous sleep laboratory experience: young [n = 11, 23.1 (0.5) years]; perimenopausal [n = 15, 48.0 (0.4) years]; postmenopausal without hormone therapy [n = 22, 63.4 (0.8) years]; and postmenopausal on hormone therapy [n = 16, 63.1 (0.9) years], using a cross‐sectional design. Polysomnography including electrocardiogram was performed over two consecutive nights. Heart rate variability was assessed overnight, and the first‐night effect on heart rate variability was analysed. Furthermore, correlations between heart rate variability and sleep variables were analysed. Using combined groups, only minor changes were observed in non‐linear heart rate variability, indicating increased parasympathetic tone from the first to the second night. No group differences in first‐night effect were seen. Heart rate variability and sleep variables were not significantly correlated. Heart rate variability decreased with increasing age, and it was lowest in the postmenopausal women on hormone therapy. We conclude that a first night in a sleep laboratory elicits only minimal changes in overnight vagally mediated non‐linear heart rate variability in women irrespective of reproductive state. This finding warrants further analyses in different sleep stages, but suggests that changes in sleep architecture per se do not predict the autonomic strain of a poor night.
Role of de‐N‐acetylase PgaB from Aggregatibacter actinomycetemcomitans in exopolysaccharide export in biofilm mode of growth
Authors: Shanmugam M. , Oyeniyi A.O. , Parthiban C. , Gujjarlapudi S.K. , Pier G.B. , Ramasubbu N. 
Published: May 2017

SummaryAggregatibacter actinomycetemcomitans, a Gram‐negative bacterium, is the causative agent of localized aggressive periodontitis. Attachment to a biotic surface is a critical first step in the A. actinomycetemcomitans infection process for which exopolysaccharides have been shown to be essential. In addition, the pga operon, containing genes encoding for biosynthetic proteins for poly‐N‐acetyl glucosamine (PNAG), plays a key role in A. actinomycetemcomitans virulence, as a mutant strain lacking the pga operon induces significantly less bone resorption. Among the genes in the pga operon, pgaB codes for a de‐N‐acetylase that is responsible for the deacetylation of the PNAG exopolysaccharide. Here we report the role of PgaB in regulation of virulence genes using a markerless, scarless deletion mutant targeting the coding region of the N‐terminal catalytic domain of PgaB. The results demonstrate that the N‐terminal, catalytic domain of PgaB is crucial for exopolysaccharide export.
Virtue Ethics is Empirically Adequate: A Defense of the Caps Response to Situationism
Authors: West Ryan 
Published: May 2017

AbstractAccording to situationists, the available empirical psychological data show that prevalent conceptions of virtue are ‘empirically inadequate.’ The charge is ambiguous. I begin by differentiating four families of empirical inadequacy charges, explaining the conceptual connections among the families, and showing how different situationists press different versions of the charges from each family. Then I explain how the empirical psychological model known as the ‘cognitive affective personality system,’ or ‘CAPS model,’ enables distinct responses to these varied charges. The CAPS response has come under fire, though, and I close by responding to the five main challenges raised against it.
Epiphytic Curtobacterium flaccumfaciens strains isolated from symptomless solanaceous vegetables are pathogenic on leguminous but not on solanaceous plants
Authors: Osdaghi E. , Taghavi S. M. , Hamzehzarghani H. , Fazliarab A. , Harveson R. M. , Tegli S. , Lamichhane J. R. 
Published: May 2017

In Iran, during 2013–16, 16 Gram‐positive corynebacteria‐like strains were recovered from the epiphytic parts of solanaceous vegetables including eggplant, pepper and tomato. The strains were recovered accidentally as a result of monitoring for other bacterial pathogens in solanaceous fields. The strains were phenotypically different from Clavibacter michiganensis strains. Although none of the strains were pathogenic on their host of isolation or on any other solanaceous plants, 12 out of 16 strains were pathogenic on common bean, cowpea, mung bean and soybean. Colonization by strains was observed on maize, zucchini, faba bean, honeydew melon, rapeseed, sugar beet and sunflower plants under greenhouse conditions. In PCR tests, the primer pair CffFOR2/CffREV4, specific for Curtobacterium flaccumfaciens pv. flaccumfaciens, enabled the amplification of the appropriately sized fragment in 12 out of 16 strains, and all 12 strains were pathogenic on dry beans. Phylogenetic analysis, using the gyrB and recA genes, showed all 16 bacterial strains clustered within several pathovars of C. flaccumfaciens. A nonpathogenic yellow‐pigmented strain (Xeu15) was clustered with the type strains of C. flaccumfaciens pv. betae and C. flaccumfaciens pv. oortii. Bacteriocin profiling assays revealed no significant differences among the pathogenic and nonpathogenic strains. Host range and population dynamics of four representative strains on 17 plant species showed population build‐up of the strains only on common bean, cowpea, wheat and red nightshade plants. The results provide important insights into the possible role of nonhost plants as reservoirs of plant pathogenic bacteria, which has important implications in plant disease epidemiology and management.
The impact of serum incubation time on IgM/IgG binding to porcine aortic endothelial cells
Authors: Zhang Zhongqiang , Gao Bingsi , Zhao Chengjiang , Long Cassandra , Qi Haizhi , Ezzelarab Mohamed , Cooper David KC , Hara Hidetaka 
Published: May 2017

AbstractThe results of the assay for measuring anti‐non‐Gal antibodies (which affect pig xenograft survival) in recipients are important. Serum incubation time and concentration may be important factors in the extent of antibody binding to the graft. The aim of this in vitro study was to determine the optimal incubation time and serum concentration for measuring anti‐non‐Gal antibody binding to porcine aortic endothelial cells (pAECs). Pooled human, naive, and sensitized baboon sera were incubated with wild‐type, α1,3‐galactosyltransferase gene‐knockout (GTKO), and GTKO/human CD55 pAECs. IgM/IgG binding to pAECs after varying serum incubation times (0.5, 1, 2, and 3 hour) and concentrations (5, 10, 20, and 40 μL) was determined by flow cytometry. An increase in incubation time from 30 minutes to 2 hour was associated with increases in anti‐non‐Gal IgM/IgG binding to GTKO and GTKO/hCD55 pAECs of pooled human, naive and sensitized baboon sera (P<.05). Pooled human serum showed a significant increase in anti‐non‐Gal IgM (1.5 times) and a minimal increase in anti‐non‐Gal IgG antibody binding. IgM/IgG binding of sensitized baboon serum to GTKO pAECs after 2‐hour incubation was 1.5 times and 2 times greater than after 30‐minutes incubation, respectively, whereas naïve baboon sera showed minimal (non‐significant) increase in anti‐non‐Gal IgM/IgG antibody binding. With 2‐hour incubation, increasing the serum concentration from 5 μL to 20 μL significantly increased antibody binding to non‐Gal antigens in pooled human and sensitized baboon serum. With naïve baboon serum, only IgG was significantly increased. Increasing the serum incubation time contributed to improve the sensitivity of detecting anti‐non‐Gal antibodies, without affecting cell viability in vitro.
Grotenhout Virus, a Novel Nairovirus Found in Ixodes ricinus in Belgium
Authors: Vanmechelen Bert , Laenen Lies , Vergote Valentijn , Maes Piet 
Published: May 2017

ABSTRACT

We report here the draft genome of a novel nairovirus, Grotenhout virus, isolated from deer ticks (
Ixodes ricinus
) in Belgium. The genome consists of two segments, L and S, and is most similar to the tick-borne South Bay virus, with amino acid identities ranging from 60 to 64%.
The Complete Genome Sequence of a Human Parechovirus from a Child with Diarrhea in China Revealed Intertypic Recombination
Authors: Zhao Xiaoying , Zhou Chenglin , Zhang Xiaodan , Li Wang , Wan Xinyu , Wang Yan , Zeng Yuming , Zhang Wen 
Published: May 2017

ABSTRACT
A human parechovirus (HPeV), CH-ZXY1, was detected in feces from a child with diarrhea. Phylogenetic trees over three different genomic regions revealed discordant topological structures. Recombination analysis indicates that CH-ZXY1 is a recombinant resulting from recombination between HPeV5 and HPeV1, which was confirmed by PCR covering the recombination breakpoint.
Complete Genome Sequence of
Streptomyces
sp. Sge12, Which Produces Antibacterial and Fungicidal Activities
Authors: Xu Jianguo , Xu Min , Liu Kai , Peng Qinyin , Tao Meifeng 
Published: May 2017

ABSTRACT

Streptomyces
sp. Sge12 was isolated from forest soil and exhibited remarkable antimicrobial activities against selected fungi and Gram-positive bacteria. Here, we report the complete genome sequence of this strain, which contains 37 putative secondary metabolite gene clusters.
Complete Genome Sequence of the Autotrophic Acetogen Clostridium formicaceticum DSM 92
T
Using Nanopore and Illumina Sequencing Data
Authors: Karl Michael M. , Poehlein Anja , Bengelsdorf Frank R. , Daniel Rolf , Dürre Peter 
Published: May 2017

ABSTRACT

Here, we report the closed genome sequence of
Clostridium formicaceticum
, an Rnf- and cytochrome-containing autotrophic acetogen that is able to convert carbon monoxide to acetate using the Wood-Ljungdahl pathway. The genome consists of a circular chromosome (4.59 Mb).
Theoretical investigation of some physicochemical properties in the liquid Sn–Ag–Cu alloys
Authors: M’chaar Rachida , Sabbar Abdelaziz , El Moudane Mouloud , Ghanimi Ahmed 
Published: May 2017

Some physicochemical properties such as surface tension, molar volume, density and viscosity of liquid Sn–Ag–Cu alloys have been calculated using Kohler, Muggianu, Toop and Hillert geometrical models along three cross-sections namely [Formula: see text]/[Formula: see text], 1/1 and 2/1. Indeed, Guggenheim, Kozlov–Romanov–Petrov and Kaptay equations have also been extended to estimate the surface tension and viscosity based on the thermodynamic data of the investigated system over wide temperature ranges of 823–1123[Formula: see text]K and 773–1173[Formula: see text]K, respectively. The results show that the three investigated properties, surface tension, density and viscosity, decrease with increasing tin for all studied models. On the other hand, a different behavior of these properties as a function of the temperature was noted. This evolution depends on the composition of the studied alloys. On the contrary, the molar volume increases with increase of temperature and tin compositions. It should be noted that the surface tension, density and molar volume show a linear dependence on temperature for all the investigated compositions. For viscosity, a curvilinear dependence has been observed. The calculated surface tensions and densities were compared with those reported experimentally for Sn–Ag–Cu alloys along the cross-section [Formula: see text]/[Formula: see text][Formula: see text]1/1.
Contemporary stress and neotectonics in the Otway Basin, southeastern Australia
Authors: Tassone David R. , Holford Simon P. , King Rosalind , Tingay Mark R. P. , Hillis Richard R. 
Published: May 2017

Abstract

Geomechanical and geological datasets from fold–thrust belts and passive margins that have been subject to neotectonic activity often provide contradictory evidence for the state of contemporary stress. Southeastern Australia has relatively high levels of neotectonic activity for a so-called stable continental region. In the eastern Otway Basin, this neotectonic activity consists of compressional deformation and uplift, indicating a reverse fault stress regime. However, this is inconsistent with the stress magnitudes estimated from petroleum exploration data, which indicate normal or strike-slip fault stress regimes. A new wellbore failure analysis of 12 wells indicates that the maximum horizontal stress azimuth in this basin is
c.
135° N, consistent with neotectonic structural trends. Our results indicate that the lithology and variations in structural style with depth exert important controls on horizontal stress magnitudes. The observed partitioning of stress regimes and deformation styles with depth within the basin may reflect the contrasting mechanical properties of the basin-fill. There is an overall increase in the minimum horizontal stress gradient of
c.
1–2 MPa km
−1
from west to east, corresponding to a change in structural style across the basin. In the central Otway Basin, rift-related faults strike near-parallel to the maximum horizontal stress azimuth and there are comparatively low levels of neotectonic activity, whereas in the eastern Otway Basin, where rift-related faults strike near-orthogonal to the maximum horizontal stress azimuth, the level of neotectonic faulting and uplift is much higher. Our results show that the integration of structural geology with geomechanical datasets can lead to improved interpretations of contemporary stresses, consistent with neotectonic observations.