bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Cr‐doping effect on white light emitting properties of Ce:YAG phosphor ceramics
Authors: Tang Yanru , Zhou Shengming , Yi Xuezhuan , Zhang Shuai , Hao Deming , Shao Xiuchen 
Published: March 2017

AbstractThe Cr/Ce‐doped YAG transparent ceramic was fabricated by the solid‐state reaction in vacuum. The Cr/Ce‐doped YAG ceramic phosphor effectively complement the red spectral component and improve the color rendering performance when excited by blue light that is due to the effective energy transfer between Cr3+ ion and Ce3+ ion. However, the energy transfer from Ce3+ to Cr3+ ion leads to energy loss and therefore the luminous efficacy of the WLED which is composed of blue LED chip and the Cr/Ce‐doped YAG ceramic phosphor decreases. The composite phase structure of ceramic phosphor is designed for improving the extraction efficacy and increasing the luminous efficacy by breaking the total internal reflection (TIR) at the interface between air and ceramic.
Microwave‐assisted YBa2Cu3O7 precursors: A fast and reliable method towards chemical precursors for superconducting films
Authors: Rijckaert Hannes , De Roo Jonathan , Roeleveld Kevin , Pollefeyt Glenn , Bennewitz Jan , Bäcker Michael , Lynen Frederic , De Keukeleere Katrien , Van Driessche Isabel 
Published: March 2017

AbstractHighly stable, pure, and anhydrous organometallic YBa2Cu3O7‐δ (YBCO) precursor solutions were prepared by dissolving commercial YBCO powder in acetone by trifluoroacetic anhydride (TFAA) or a mixture of TFAA with propionic acid for low fluorine precursors. It is shown that compared to conventional oil bath heating reported in literature, the reaction to produce YBCO precursor occurs 72 times faster by microwave heating. More importantly, the formation of byproducts is suppressed, as shown by nuclear magnetic resonance (NMR) and mass spectrometry (MS). This approach allows a highly reproducible preparation of superconducting coatings which is of interest for low‐cost manufacturing processes capable of large‐scale production of the coated conductors via chemical solution deposition (CSD). This technology requires reliable and stable precursor solutions for continuous deposition. In this work, we obtained YBCO thin films on single‐crystal substrates ((100)‐LaAlO3) with a high critical current density (Jc) of 3‐4 MA/cm² in self‐field at 77 K using TFA‐based YBCO precursors and Jc of 5‐6 MA/cm² using low fluorine YBCO precursors.
Anionic effect of chloride, fluoride, and sulfide ions on the viscosity of slag melt
Authors: Lee Sunghee , Min Dong Joon 
Published: March 2017

AbstractThe effect of the addition of CaX (X=Cl2, F2 and S) on the viscous behavior and structure of CaO–SiO2–Al2O3–MgO–CaX slag was investigated by measuring its viscosity. The viscosity of the slag without CaX gradually decreased with an increase in the C/S ratio because of the depolymerization of the silicate groups in the slag. While the viscosity of the CaX‐bearing slag decreased with an increase in the CaX content, depolymerization was not observed in this case. Three distinct compositional regions for the activation energy of the viscous flow were observed because of the effect of the equilibrium of the polymeric silicate groups. The relaxation effect of the CaX groups on the activation energy was also observed. Raman spectroscopic analysis indicated that the relaxation in the viscosity and activation energy by CaX addition stemmed from the breaking of the NBO‐M2+‐NBO linkage to form NBO‐M2+‐F−, NBO‐M2+‐Cl−, or M2+‐S2−. All these results are discussed in detail with the help of a viscous flow model based on the ionic interactions.
Ecological diversification of the Australian Coptotermes termites and the evolution of mound building
Authors: Lee Timothy R. C. , Evans Theodore A. , Cameron Stephen L. , Hochuli Dieter F. , Ho Simon Y. W. , Lo Nathan 
Published: March 2017

AbstractAimThe Australian Coptotermes (Family: Rhinotermitidae) are a small monophyletic group of termites, some of which build mounds. In this study, we construct predicted distributions based on environmental data (niche models) for all Australian species of Coptotermes to test whether specific environmental factors have contributed to the evolution of mound‐building behaviour and whether the degree of niche similarity and degree of phylogenetic similarity are correlated.LocationThe Australian mainland, including the known native ranges of all Australian species of Coptotermes.MethodsWe estimated the phylogenetic relationships between the species of Australian Coptotermes. We then generated and compared environmental niche models in a phylogenetic framework for all study species to test niche conservation. Our analyses were based on location data from our own sampling and from the Atlas of Living Australia, genetic data from a previous study of Australian Coptotermes, and environmental data from WorldClim and ASRIS.ResultsWe found that no environmental variable differed consistently between mound‐building and non‐mound‐building taxa and that the differences in niches between pairs of Australian species of Coptotermes are uncorrelated with time since divergence. The environmental tolerances of the Australian Coptotermes termites are more restricted by rainfall than they are by soil or temperature.Main conclusionsOur results show that mound‐building behaviour has not necessarily evolved in response to similar abiotic conditions. Our results are consistent with ecological speciation leading to niche divergence since Coptotermes first arrived in Australia ~12.5 million years ago.
Cathelicidin‐encoding Lactococcus lactis promotes mucosal repair in murine experimental colitis
Authors: Wong Clover C M , Zhang Lin , Wu William K K , Shen Jing , Chan Ruby L Y , Lu Lan , Hu Wei , Li Ming X , Li Long F , Ren Shun X , Li Yi F , Li Jiang , Cho Chi H 
Published: March 2017

AbstractBackground and AimThe preventive effect of intrarectal administration of mouse cathelicidin (mCRAMP) and oral administration of mCRAMP‐encoding Lactococcus lactis (N4I) has been shown in murine experimental colitis. It is pivotal to understand the ability of N4I whether it can promote mucosal repair in existing colitis.MethodsMice with dextran sulfate sodium‐induced ulcerative colitis (UC) were treated orally with L. lactis or its transformed strain with or without nisin induction. The body weight, clinical symptoms, and histological changes of colonic tissues were determined. Sulfasalazine was used as a reference drug. Young adult mouse colon cells were used to further elucidate the direct action and possible mechanisms of mCRAMP to promote colonic wound repair.ResultsResults showed that N4I could improve the clinical symptoms, maintain crypt integrity and preserve mucus‐secreting layer in colitis animals. The preparation also could prevent cell death and promote cell proliferation. In contrast, effective dose of sulfasalazine only alleviated clinical symptoms but not the mucosal damage and repair in the colon. In vitro study further showed that mCRAMP could directly promote wound repair by accelerating cell migration but not cell proliferation through the GPCR/MAPK pathway.ConclusionsmCRAMP‐encoding L. lactis could be a potential therapeutic preparation better than the traditional anti‐inflammatory agent in the treatment of UC.
Actor and Partner Effects of Attachment on Relationship Satisfaction and Sexual Satisfaction Across the Genders: An APIM Approach
Authors: Conradi Henk Jan , Noordhof Arjen , Dingemanse Pieter , Barelds Dick P. H. , Kamphuis Jan H. 
Published: March 2017

Previous studies found gender differences in relationship satisfaction and sexuality. We tested gender differences in associations between attachment, a lasting relationship determinant, and two outcomes, relationship and sexual satisfaction. This study improves on earlier research by examining these associations in one Actor‐Partner‐Interdependence‐Model, making direct statistical testing between outcomes possible. Furthermore, a community and a distressed sample (N = 113 heterosexual couples each) were included to attempt replication across samples and to examine clinical implications. In both genders, actor attachment avoidance negatively affected relationship satisfaction and (with one exception) sexual satisfaction. Also in both genders, partner attachment avoidance negatively affected sexual satisfaction. However, whereas partner attachment avoidance influenced female relationship satisfaction, it did not affect male relationship satisfaction. The findings replicated across samples. Clinical implications are discussed.
MRF‐ANN: a machine learning approach for automated ER scoring of breast cancer immunohistochemical images
Authors: MUNGLE T. , TEWARY S. , DAS D.K. , ARUN I. , BASAK B. , AGARWAL S. , AHMED R. , CHATTERJEE S. , CHAKRABORTY C. 
Published: March 2017

SummaryMolecular pathology, especially immunohistochemistry, plays an important role in evaluating hormone receptor status along with diagnosis of breast cancer. Time‐consumption and inter‐/intraobserver variability are major hindrances for evaluating the receptor score. In view of this, the paper proposes an automated Allred Scoring methodology for estrogen receptor (ER). White balancing is used to normalize the colour image taking into consideration colour variation during staining in different labs. Markov random field model with expectation‐maximization optimization is employed to segment the ER cells. The proposed segmentation methodology is found to have F‐measure 0.95. Artificial neural network is subsequently used to obtain intensity‐based score for ER cells, from pixel colour intensity features. Simultaneously, proportion score – percentage of ER positive cells is computed via cell counting. The final ER score is computed by adding intensity and proportion scores – a standard Allred scoring system followed by pathologists. The classification accuracy for classification of cells by classifier in terms of F‐measure is 0.9626. The problem of subjective interobserver ability is addressed by quantifying ER score from two expert pathologist and proposed methodology. The intraclass correlation achieved is greater than 0.90. The study has potential advantage of assisting pathologist in decision making over manual procedure and could evolve as a part of automated decision support system with other receptor scoring/analysis procedure.
Label‐free identification of the microstructure of rat spinal cords based on nonlinear optical microscopy
Authors: LIAO C.X. , WANG Z.Y. , ZHOU Y. , ZHOU L.Q. , ZHU X.Q. , LIU W.G. , CHEN J.X. 
Published: March 2017

SummaryThe spinal cord is a vital link between the brain and the body and mainly comprises neurons, glial cells and nerve fibres. In this work, nonlinear optical (NLO) microscopy based on intrinsic tissue properties was employed to label‐freely analyze the cells and matrix in spinal cords at a molecular level. The high‐resolution and high‐contrast NLO images of unstained spinal cords demonstrate that NLO microscopy has the ability to show the microstructure of white and grey matter including ventral horn, intermediate area, dorsal horns, ventral column, lateral column and dorsal column. Neurons with various sizes were identified in grey matter by dark spots of nonfluorescent nuclei encircled by cytoplasm‐emitting two‐photon excited fluorescence signals. Nerve fibres and neuroglias were observed in white matter. Besides, the spinal arteries were clearly presented by NLO microscopy. Using spectral and morphological information, this technique was proved to be an effective tool for label‐freely imaging spinal cord tissues, based on endogenous signals in biological tissue. With future development, we foresee promising applications of the NLO technique for in vivo, real‐time assessment of spinal cord diseases or injures.
Age discrimination within a P‐E fit paradigm: Maintaining fit with an active work style
Authors: Bayl‐Smith Piers , Griffin Barbara 
Published: March 2017

In the context of work environment and within‐person change, age discrimination represents a substantial and important challenge for mid‐ to late‐career workers. This present research expands the current literature by examining age discrimination within a P‐E fit paradigm. Utilizing the theory of work adjustment, we examined the effect of perceived age discrimination upon demands–abilities (D‐A) fit and needs–supplies (N‐S) fit in two, two‐wave studies. Consistent with hypotheses, Study 1 (N = 1345) demonstrated that as individuals perceived increasing experiences of age discrimination, both D‐A and N‐S fit decreased over time. Study 2 (N = 665) included active work styles, defined as an individual's general level and pattern of workplace effort and activity, as a possible moderating variable of the relationship between age discrimination and D‐A fit. As expected, the engagement of a highly active work style ameliorated the deleterious effects of age discrimination. Implications for future empirical research and possible workplace applications deriving from these studies are discussed.Practitioner points

Age discrimination has a negative impact upon employees being able to maintain their fit with the work environment.

An employee may minimize the impact of age discrimination by maintaining a highly active work style.

Organizations need to facilitate a positive age diversity climate by actively challenging negative stereotypes through education and training programmes, and the enforcement of fair and just diversity policies.
Accuracy of Self‐Esteem Judgments at Zero Acquaintance
Authors: Hirschmüller Sarah , Schmukle Stefan C. , Krause Sascha , Back Mitja D. , Egloff Boris 
Published: March 2017

AbstractObjectivePerceptions of strangers’ self‐esteem can have wide‐ranging interpersonal consequences. Aiming to reconcile inconsistent results from previous research that had predominantly suggested that self‐esteem is a trait that can hardly be accurately judged at zero acquaintance, we examined unaquainted others’ accuracy in inferring individuals’ actual self‐esteem.MethodNinety‐nine target participants (77 female;Mage = 23.5 years) were videotaped in a self‐introductory situation, and self‐esteem self‐reports and reports by well‐known informants were obtained as separate accuracy criteria. Forty unacquainted observers judged targets' self‐esteem on the basis of these short video sequences (M = 23s,SD = 7.7).ResultsResults showed that both self‐reported (r = .31,p = .002) and informant‐reported self‐esteem (r = .21,p = .040) of targets could be inferred by strangers. The degree of accuracy in self‐esteem judgments could be explained with lens model analyses: Self‐ and informant‐reported self‐esteem predicted nonverbal and vocal friendliness, both of which predicted self‐esteem judgments by observers. In addition, observers’ accuracy in inferring informant‐reported self‐esteem was mediated by the utilization of targets’ physical attractiveness. Besides using valid behavioral information to infer strangers’ self‐esteem, observers inappropriately relied on invalid behavioral information reflecting nonverbal, vocal, and verbal self‐assuredness.ConclusionsOur findings show that strangers can quite accurately detect individuals’ self‐reported and informant‐reported self‐esteem when targets are observed in a public self‐presentational situation.
Comparative pharmacokinetic evaluation of lopinavir and lopinavir-loaded solid lipid nanoparticles in hepatic impaired rat model
Authors: Ravi Punna Rao , Vats Rahul 
Published: March 2017

Abstract

Objective
Drug-induced hepatotoxicity is a major cause of concern in patients receiving HIV/TB co-treatment. Lopinavir (LPV), an anti-HIV drug, shows poor plasma exposure due to hepatic first-pass metabolism. In this study, we investigated the effect of hepatotoxicity on pharmacokinetics of free LPV and LPV-loaded solid lipid nanoparticles (LPV SLNs) in male Wistar rats.

Methods
Hepatic impairment model in rats was developed by injecting CCl4 (i.p., 2 ml/kg). Comparative pharmacokinetic (n = 5) and tissue distribution studies (n = 3) were conducted following oral administration (20 mg/kg) of free LPV and LPV SLNs in normal and hepatic impaired rats. Isolated perfused liver (IPL) model (n = 3) and cycloheximide intervened lymphatic uptake studies (n = 3) were conducted to appreciate disposition pattern of LPV.

Key findings
In contrary to free LPV, pharmacokinetic results demonstrated no significant (P &gt; 0.05) difference in drug plasma profile of LPV SLNs in normal and impaired rats. IPL model demonstrated trivial role of liver in disposition of LPV SLNs. Tissue distribution studies of SLNs showed higher (P &lt; 0.05) LPV accumulation in lymphoidal organs. Pretreatment of cycloheximide significantly (P &lt; 0.05) reduced AUC and Cmax of LPV SLNs.

Conclusion
From the results, we conclude that unlike conventional formulations of LPV, disposition characteristics of LPV SLNs were similar both in normal and hepatic impaired rats.
Epistemic/Non‐epistemic Dependence
Authors: Zangwill Nick 
Published: March 2017

AbstractI foreground the principle of epistemic dependence. I isolate that relation and distinguish it from other relations and note what it does and does not entail. In particular, I distinguish between dependence and necessitation. This has many interesting consequences. On the negative side, many standard arguments in epistemology are subverted. More positively, once we are liberated from the necessary and sufficient conditions project, many fruitful paths for future epistemological investigation open up. I argue that that not being defeated does not make for knowledge. And I argue for the multiple realization of epistemic properties in non‐epistemic properties.
A new location to split Cre recombinase for protein fragment complementation
Authors: Rajaee Maryam , Ow David W. 
Published: March 2017

SummaryWe have previously described a recombinase‐mediated gene stacking system in which the Cre recombinase is used to remove lox‐site flanked DNA no longer needed after each round of Bxb1 integrase‐mediated site‐specific integration. The Cre recombinase can be conveniently introduced by hybridization with a cre‐expressing plant. However, maintaining an efficient cre‐expressing line over many generations can be a problem, as high production of this DNA‐binding protein might interfere with normal chromosome activities. To counter this selection against high Cre activity, we considered a split‐cre approach, in which Cre activity is reconstituted after separate parts of Cre are brought into the same genome by hybridization. To insure that the recombinase‐mediated gene stacking system retains its freedom to operate, we tested for new locations to split Cre into complementing fragments. In this study, we describe testing four new locations for splitting the Cre recombinase for protein fragment complementation and show that the two fragments of Cre split between Lys244 and Asn245 can reconstitute activity that is comparable to that of wild‐type Cre.
A collection of enhancer trap insertional mutants for functional genomics in tomato
Authors: Pérez‐Martín Fernando , Yuste‐Lisbona Fernando J. , Pineda Benito , Angarita‐Díaz María Pilar , García‐Sogo Begoña , Antón Teresa , Sánchez Sibilla , Giménez Estela , Atarés Alejandro , Fernández‐Lozano Antonia , Ortíz‐Atienza Ana , García‐Alcázar Manuel , Castañeda Laura , Fonseca Rocío , Capel Carmen , Goergen Geraldine , Sánchez Jorge , Quispe Jorge L. , Capel Juan , Angosto Trinidad , Moreno Vicente , Lozano Rafael 
Published: March 2017

SummaryWith the completion of genome sequencing projects, the next challenge is to close the gap between gene annotation and gene functional assignment. Genomic tools to identify gene functions are based on the analysis of phenotypic variations between a wild type and its mutant; hence, mutant collections are a valuable resource. In this sense, T‐DNA collections allow for an easy and straightforward identification of the tagged gene, serving as the basis of both forward and reverse genetic strategies. This study reports on the phenotypic and molecular characterization of an enhancer trap T‐DNA collection in tomato (Solanum lycopersicum L.), which has been produced by Agrobacterium‐mediated transformation using a binary vector bearing a minimal promoter fused to the uidA reporter gene. Two genes have been isolated from different T‐DNA mutants, one of these genes codes for a UTP‐glucose‐1‐phosphate uridylyltransferase involved in programmed cell death and leaf development, which means a novel gene function reported in tomato. Together, our results support that enhancer trapping is a powerful tool to identify novel genes and regulatory elements in tomato and that this T‐DNA mutant collection represents a highly valuable resource for functional analyses in this fleshy‐fruited model species.
Congenital Degos Disease: Case Report and Dermoscopic Findings
Authors: Calderón‐Castrat Ximena , Castro Rosa , Peceros‐Escalante Johanna , Villate Caballero Marjorie , Chian Cesar , Ballona Rosalía 
Published: March 2017

AbstractPediatric Degos disease is rare, with only 36 cases reported in the medical literature. Classically the diagnosis has been established according to pathognomonic histopathologic findings, but when these features are not present, there may be a delay in diagnosis. We report the second congenital case of Degos disease, highlighting the clinical and dermoscopic findings.
The Influence of Plan Demographics on Contribution Behavior of 401(k) Participants
Authors: Park Youngkyun 
Published: March 2017

AbstractThis article examines the influence of plan demographics, which is defined as the salary and tenure composition of a plan, on contribution behavior of 401(k) participants. Results using a large sample of 401(k) plans show that plan demographics influence participant contribution rates directly or through interaction with individual demographic characteristics. A participant's contribution rate can be varied by 1.6–3.0 percentage points for each age between 25 and 64, depending on what plan demographics she is exposed to. In addition, for the decision to contribute the maximum allowed amount, plan demographics significantly interact with individual demographic characteristics.
Yes We Can (Price Derivatives on Survivor Indices)
Authors: Boyer M. Martin , Stentoft Lars 
Published: March 2017

AbstractWe propose a simulation approach to value derivatives when the underlying dynamics are estimated using the survivor indices directly. Our results show that survivor forward and swap premiums increase with maturity and with the market price of risk. Our results also confirm that taking the optionality into consideration is important from a pricing perspective, for both U.S. women and men. We compare our results to what is obtained using an alternative modeling approach in which a Lee–Carter model is used to indirectly model the survivor index. Compared to this method, our estimated premiums and prices are higher for all longevity products. Moreover, comparing American‐style with European‐style options we find that, although the early exercise option has value when using survivor indices directly, the relative value of the early exercise option is significantly less than when the Lee–Carter model is used to indirectly model the survivor index. It follows that the assumed mortality dynamics have important implications for the term structure of forward and swap premiums and for the effect that changes in the market price of risk has on them.