bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimising peripheral venous catheter usage in the general inpatient ward: a prospective observational study
Authors: Tan Ying Hua Grace , Tai Wai Ling Stephanie , Sim Crystal , Ng Hui Leng Isabel 
Published: June 2016

Aims and objectivesTo evaluate current practices in managing peripheral venous catheters through catheter lifespan, reasons for removal and identifying potential predictors of catheter complications.BackgroundPeripheral venous catheter insertion is a common minimally invasive procedure performed during patient admission. Current routine replacement of catheters may not be required in the light of recent evidence.DesignA prospective observational study was carried out in April 2013.MethodsOne hundred patients were selected by systematic sampling. Ward nurses with support from three research nurses collected data for two weeks, ceasing earlier if patient no longer required venous catheters, was discharged, passed on or was transferred to a nongeneral ward setting. Analysis for potential predictors was carried out using random‐effects model.ResultsA total of 218 catheters were sampled, with a median catheter lifespan of 2·0 days. Half the catheters were removed because of complications with only 13 catheter removals due to phlebitis (grade 1+) in the first three days. Percentage of catheters removed due to complications also decreased as indwelling time increased. Twenty‐three catheters (8·3%) could also have been saved as they were rendered ‘not required/discharge’ on day 1. Only insertion on the outer forearm was found to be associated with the likelihood of developing venous catheter complications.ConclusionsPhlebitis rates in our setting are comparable to other published studies with all phlebitis cases occurring before the third day. The median catheter lifespan of two days is shorter than routine three‐day replacement, which warrants an urgent review of current insertion and maintenance practices in our local setting.Relevance to clinical practiceChanging practice from routine replacement to clinically indicated has benefits to nurses and patients in terms of manpower time and costs. However, an effort to maximise peripheral catheter lifespan is necessary through daily vigilant catheter care and regular audits of practices.
Dental hygiene registration: development, and reliability and validity testing of an assessment scale designed for nurses in institutions
Authors: Fjeld Katrine Gahre , Eide Hilde , Mowe Morten , Hove Lene Hystad , Willumsen Tiril 
Published: June 2016

Aims and objectivesTo develop and test the dental hygiene registration, a dental hygiene assessment scale for nurses working in institutions.BackgroundRemoval of dental plaque is a key factor in preventing oral health‐related diseases. A simple, but reliable dental hygiene assessment scale that enables nurses to monitor residents’ dental hygiene on a daily basis, will improve monitoring oral hygiene status and quality of dental health care.DesignDescriptive study on the development and evaluation of a dental hygiene registration instrument.MethodsThe dental hygiene registration was developed and tested over several stages during the period of 2011–2014. Dental hygiene registration consists of a five‐point plaque score scale. The score indicates whether measures are needed. A reference group comprising both medical and dental personnel designed dental hygiene registration. Dental plaque was used as a measure of dental hygiene. A pictorial series of teeth with varying amounts of plaque was used to achieve intra‐examiner agreement. Dental hygiene registration assessments were scored 50 times to assess interexaminer reliability between one dental hygienist and one clinical nurse. Dental hygiene registration was validated against the plaque index score of the Simplified Oral Hygiene Index. The Regional Ethics Committee approved the study (2011/915).ResultsEstimates for intra‐examiner agreement on plaque score were good for the dental hygienist (κ = 0·7) and very good for the clinical nurse (κ = 0·8). Estimates for interexaminer reliability for dental hygiene registration between the dental hygienist and the clinical nurse were moderate (κ = 0·4). dental hygiene registration corresponded significantly with Simplified Oral Hygiene Index (Spearman's correlation coefficient = 0·8, p < 0·001) indicating good validity.ConclusionThe developed dental hygiene registration appears to be reliable and valid.Relevance to clinical practiceDental hygiene registration may contribute to the provision of daily oral care. Dental hygiene registration enables nurses to evaluate their own effort when assisting in dental hygiene and to register whether further effort is needed.
Sexual health in primary health care – a qualitative study of nurses’ experiences
Authors: Klaeson Kicki , Hovlin Lina , Guvå Hanna , Kjellsdotter Anna 
Published: June 2016

Aim and objectivesTo illuminate nurses’ experiences and opportunities to discuss sexual health with patients in primary health care.BackgroundSexual health is a concept associated with many taboos, and research shows that nurses feel uncomfortable talking to patients about sexual health and therefore avoid it. This avoidance forms a barrier between patient and nurse which prevents nurses from giving satisfactory health care to patients.DesignA qualitative descriptive design.MethodSemi‐structured interviews were conducted with nine nurses in primary health care in Sweden. Data were analysed using qualitative content analysis.ResultsDuring the analysis phase, five subcategories and two main categories were identified. The two main categories were as follows: ‘factors that influence nurses’ opportunities of talking to patients about sexual health’ and ‘nurses’ experiences of talking to patients about sexual health’. Social norms in society were an obstacle for health professionals’ opportunities to feel comfortable and act professionally. The nurses’ personal attitude and knowledge were of great significance in determining whether they brought up the topic of sexual health or not. The nurses found it easier to bring up the topic of sexual health with middle‐aged men with, for example, diabetes. One reason for this is that they found it easier to talk to male patients. A further reason is the fact that they had received training in discussing matters of sexual health in relation to diabetes and other conditions affecting sexual health.ConclusionNurses in primary care express the necessity of additional education and knowledge on the subject of sexual health. The healthcare organisation must be reformed to put focus on sexual health.Relevance for clinical practiceGuidelines for addressing the topic of sexual health must be implemented to establish conditions that will increase nurse's knowledge and provide them with the necessary tools for discussing sexual health with patients.
Severe pneumonia caused by adenovirus 7 in pregnant woman: Case report and review of the literature
Authors: Liao Ji‐ping , Wang Guang‐fa , Jin Zhe , Qian Yuan , Deng Jie , Que Cheng‐li 
Published: June 2016

AbstractWe report a rare case of adenoviral pneumonia in a previously healthy pregnant woman at 26+4 weeks' gestation. She presented with persistent high fever, cough for 5 days, and developed progressive dyspnea with hypoxemic respiratory failure and bilateral pulmonary infiltrates with pleural effusions. Aggressive supportive care and timely obstetrical management saved the mother and prevented preterm delivery and fetal anomaly.
Technology‐Based Communication and the Development of Interpersonal Competencies Within Adolescent Romantic Relationships: A Preliminary Investigation
Authors: Nesi Jacqueline , Widman Laura , Choukas‐Bradley Sophia , Prinstein Mitchell J. 
Published: June 2016

This study investigated longitudinal associations between adolescents’ technology‐based communication and the development of interpersonal competencies within romantic relationships. A school‐based sample of 487 adolescents (58% girls; Mage = 14.1) participated at two time points, one year apart. Participants reported (1) proportions of daily communication with romantic partners via traditional modes (in person, on the phone) versus technological modes (text messaging, social networking sites) and (2) competence in the romantic relationship skill domains of negative assertion and conflict management. Results of cross‐lagged panel models indicated that adolescents who engaged in greater proportions of technology‐based communication with romantic partners reported lower levels of interpersonal competencies one year later, but not vice versa; associations were particularly strong for boys.
Automatic Inventory of Road Cross‐Sections from Mobile Laser Scanning System
Authors: Holgado‐Barco Alberto , Riveiro Belén , González‐Aguilera Diego , Arias Pedro 
Published: June 2016

AbstractThis article aims to automatically obtain the geometrical inventory of road cross‐sections (i.e., number of lanes, width of the roadway, width of the shoulders, width of the lanes, superelevation) using a mobile laser scanning (MLS) system. Because of the large amount of data captured by the MLS, we have developed a methodology that is based on a process of segmentation, classification, and extraction, which allows us to determine the geometrical cross‐section parameters. The process was validated with real data from motorways, and satisfactory results were obtained in the analyzed scenarios.
Dietary patterns and prevalence of irritable bowel syndrome in Iranian adults
Authors: Khayyatzadeh S. S. , Esmaillzadeh A. , Saneei P. , Keshteli A. H. , Adibi P. 
Published: June 2016

AbstractBackgroundAlthough several dietary factors have been reported to alleviate or aggravate the symptoms of irritable bowel syndrome (IBS), no information is available linking habitual dietary patterns to irritable bowel syndrome.ObjectiveThis study was undertaken to assess the association between dietary patterns and the risk of IBS among Iranian adults.MethodsIn this cross‐sectional study, data on 3846 Iranian adults working in 50 different health centers were examined. Dietary intake of study participants was assessed using a 106‐item self‐administered Dish‐based Semi‐quantitative Food Frequency Questionnaire (DS‐FFQ) which was designed and validated specifically for Iranian adults. To identify major dietary patterns based on the 39 food groups, we used principal component analysis. A modified Persian version of the Rome III questionnaire was used for assessment of IBS.ResultsWe identified four major dietary patterns: (i) ‘fast food’, (ii) ‘traditional’, (iii) ‘lacto‐vegetarian’, and (iv) ‘western’ dietary pattern. After adjustment for potential confounders, we found that those in the highest quartile of ‘fast food’ dietary pattern were tended to have higher risk of IBS than those in the lowest quartile (OR = 1.32; 95% CI: 0.99, 1.75, ptrend = 0.05). An inverse association was also found between ‘lacto‐vegetarian’ dietary pattern and risk of IBS; such that even after adjustment for potential confounders, those in top quartile of this dietary pattern were 24% less likely to have IBS (0.76; 0.59, 0.98; ptrend = 0.02). No overall significant associations were observed between ‘traditional’ and ‘western’ dietary patterns and risk of IBS, either before or after adjustment for covariates.ConclusionWe found that ‘lacto‐vegetarian’ dietary pattern was associated with reduced risk, while ‘fast food’ dietary pattern was associated with a greater risk of IBS in Iranian adults.
A genome‐wide association study in Caucasian women suggests the involvement of HLA genes in the severity of facial solar lentigines
Authors: Laville Vincent , Clerc Sigrid Le , Ezzedine Khaled , Jdid Randa , Taing Lieng , Labib Taoufik , Coulonges Cedric , Ulveling Damien , Carpentier Wassila , Galan Pilar , Hercberg Serge , Morizot Frederique , Latreille Julie , Malvy Denis , Tschachler Erwin , Zagury Jean‐François 
Published: June 2016

SummarySolar lentigines are a common feature of sun‐induced skin ageing. Little is known, however, about the genetic factors contributing to their development. In this genome‐wide association study, we aimed to identify genetic loci associated with solar lentigines on the face in 502 middle‐aged French women. Nine SNPs, gathered in two independent blocks on chromosome 6, exhibited a false discovery rate below 25% when looking for associations with the facial lentigine score. The first block, in the 6p22 region, corresponded to intergenic SNPs and also exhibited a significant association with forehead lentigines (P = 1.37 × 10−8). The second block, within the 6p21 HLA region, was associated with decreased HLA‐C expression according to several eQTL databases. Interestingly, these SNPs were also in high linkage disequilibrium with the HLA‐C*0701 allele (r2 = 0.95). We replicated an association recently found by GWAS in the IRF4 gene. Finally, a complementary study on 44 selected candidate SNPs revealed novel associations in the MITF gene. Overall, our results point to several mechanisms involved in the severity of facial lentigines, including HLA/immunity and the melanogenesis pathway.
Double inlet left ventricle–ventriculoarterial discordance without surgical treatment
Authors: Güvenç Osman , Saygi Murat , Şengül Fatma S , Ayyıldız Pelin , Güzeltaş Alper 
Published: June 2016

AbstractUniventricular heart is a rare congenital defect that consists, in nearly 80% of cases, of double inlet left ventricle, to which both atrioventricular valves connect. A 31‐year‐old male patient was diagnosed with single ventricle at the age of 9. He had not received any surgical intervention and was not on any medication. Functional capacity was assessed as New York Heart Association class III. Both atrioventricular valves were found to open into the morphological left ventricle, which was located on the right; the hypoplasic right ventricle was on the left side of the left ventricle, the posteriorly located aorta emerged from the right ventricle, and the anteriorly located pulmonary artery emerged from the left ventricle. There was significant subvalvular and valvular stenosis in the pulmonary valve site. The disease is complex and it is very rare that untreated patients reach adulthood.
Does Dent disease remain an underrecognized cause for young boys with focal glomerulosclerosis?
Authors: Kubo Kaori , Aizawa Tomomi , Watanabe Shojiro , Tsugawa Koji , Tsuruga Kazushi , Ito Etsuro , Joh Kensuke , Tanaka Hiroshi 
Published: June 2016

AbstractFocal glomerulosclerosis (FGS) is a histologic entity that causes significant proteinuria in children. Although its etiology varies, recent reports indicated that some young male patients with FGS had underlying Dent disease. We describe the case of a 14‐year‐old Japanese boy who presented with persistent non‐nephrotic range proteinuria, hematuria, and renal insufficiency. The patient was initially diagnosed as having FGS associated with scattered tubulointerstitial fibrosis. Although he had neither nephrocalcinosis nor family history of renal disease including urolithiasis, increased excretion of urinary β2 microglobulin was noted. Genetic analysis for Dent disease indicated a mutation (c.726 + 1G > A) in Chloride Channel, Voltage‐Sensitive 5 (CLCN5). Given a recent hypothesis that Dent disease may be underrecognized in children with FGS, a careful diagnostic evaluation for possible underlying Dent disease should be considered in young boys who present with persistent albuminuria associated with high‐grade low‐molecular‐weight proteinuria.
Cobalamin C defect‐hemolytic uremic syndrome caused by new mutation in MMACHC
Authors: Adrovic Amra , Canpolat Nur , Caliskan Salim , Sever Lale , Kıykım Ertugrul , Agbas Ayse , Baumgartner Matthias R 
Published: June 2016

AbstractAtypical hemolytic uremic syndrome (aHUS) is mostly linked to defects in the regulation of alternative complement pathway, but a rare form is caused by an inherited defect of cobalamin 1 metabolism. Cobalamin C (cblC) deficiency is an autosomal recessive disorder of vitamin B12 metabolism that results from mutations in methylmalonic aciduria and homocysteinuria (MMACHC). The most severe form of cblC deficiency and the associated high mortality rate are mostly observed in neonates or in infants <6 months of age. Early diagnosis of cblC deficiency leads to early treatment and an improved prognosis. We describe the case of a 6‐year‐old girl with cblC disorder, who presented with severe multiorgan involvement at the age of 5 months and who was successfully treated with vitamin B12, betaine, coenzyme Q10 and l‐carnitene, and who had a new homozygous mutation of MMACHC.
Wernicke's encephalopathy in a child with Down syndrome, undergoing treatment for acute lymphoblastic leukemia
Authors: Yıldırım Ayşen Türedi , Bilgili Gökmen , Akman Bilge , Ovalı Gülgün Yılmaz , Özgüven Ali Aykan , Gülen Hüseyin 
Published: June 2016

AbstractWernicke's encephalopathy (WE), the early diagnosis of which is crucial to prevent permanent sequelae, is an acute neurologic disorder that develops due to thiamine deficiency, and which is associated with considerable morbidity and mortality. A 10‐year‐old boy diagnosed with Down syndrome and acute lymphoblastic leukemia had severe vomiting and impaired consciousness following methotrexate treatment at a dose of 1 g/m2. Biochemistry was consistent with the syndrome of inappropriate anti‐diuretic hormone secretion. Level of consciousness did not improve following meticulous correction of hyponatremia, therefore cranial magnetic resonance imaging was done, which indicated specific findings consistent with WE. It should be kept in mind that Down syndrome patients are more likely to incur toxic side‐effects of chemotherapeutic agents, and thus neurological complications such as WE may occur.
Multidisciplinary treatment for prepubertal juvenile myasthenia gravis with crisis
Authors: Hirata Yusuke , Inoue Masayoshi , Nabatame Shin , Okumura Meinoshin , Ozono Keiichi 
Published: June 2016

AbstractThe management of juvenile myasthenia gravis (MG) remains controversial. We report herein the case of a 12‐year‐old girl with prepubertal juvenile MG with respiratory crisis who underwent thymectomy following methylprednisolone pulse therapy. The patient initially developed progressively worsening fatigability, eyelid ptosis, and diplopia, followed by worsening generalized weakness, dysphagia, and dyspnea. Even after i.v. immunoglobulin, the patient presented with rapid onset of severe dyspnea requiring respiratory support with mechanical ventilation and was graded as Myasthenia Gravis Foundation of America class V. After a course of i.v. methylprednisolone pulse therapy, successful control of respiratory crisis was achieved, and trans‐sternal thymectomy was performed. Partial remission was achieved postoperatively with oral pyridostigmine without immunosuppressive agents such as steroids or calcineurin inhibitors for 18 months after thymectomy. Early thymectomy following induction methylprednisolone pulse therapy might be a treatment option for prepubertal juvenile MG with severe respiratory crisis.
Detection of parasites in children with chronic diarrhea
Authors: Maçin Salih , Kaya Filiz , Çağdaş Deniz , Hizarcioglu‐Gulsen Hayriye , Saltik‐Temizel Inci Nur , Tezcan İlhan , Demir Hülya , Ergüven Sibel , Akyön Yakut 
Published: June 2016

AbstractThe aim of this study was to investigate the frequency of intestinal parasites in patients with chronic diarrhea and clarify the importance of these parasitic pathogens in such cases. A total of 60 pediatric patients with chronic diarrhea between June 2012 and October 2014 were enrolled in the study. Out of 60 stool samples, five were positive for Giardia lamblia, two, Dientamoeba fragilis, and one, Blastocystis hominis. One stool sample was positive for Entamoeba hartmanni and B. hominis, another one was positive for G. lamblia and B. hominis, another, G. lamblia and E. hartmanni and one sample was positive for Enterobius vermicularis, D. fragilis and B. hominis together. Parasitic infection, which decreases quality of life and increases susceptibility to other infections, should not be neglected, particularly in patients with chronic diarrhea. Accurate diagnosis decreases morbidity and mortality in patients with parasite infection.
Displacement of the anterior leaflet of the tricuspid valve: Rare variant of Ebstein's anomaly
Authors: Tsujii Nobuyuki , Kurosaki Kenichi , Yasuda Kenji , Mizuno Masanori , Sakaguchi Heima , Hoashi Takaya , Ichikawa Hajime , Shiraishi Isao 
Published: June 2016

AbstractIn Ebstein's anomaly, the points of attachment, or hinges, of the septal and mural leaflets in the right ventricle are displaced away from the atrioventricular junction. In contrast, the junctional hinge of the anterior leaflet usually retains a normal position. Here, we report a case of giant right atrial aneurysm due to isolated displacement of the anterior leaflet of the tricuspid valve in an infant, a rare variant of Ebstein's anomaly. Enlargement of the right atrium, which was initially diagnosed during the fetal period, progressively and markedly dilated after birth and was successfully treated with surgical resection. Isolated displacement of the anterior leaflet should be recognized as a variant of Ebstein's anomaly.
Ewing sarcoma/primitive neuroectodermal tumor of the kidney treated with chemotherapy including ifosfamide
Authors: Yoshihara Hiroki , Kamiya Takahiro , Hosoya Yosuke , Hasegawa Daisuke , Ogawa Chitose , Asanuma Hiroshi , Mizuno Ryuichi , Hosoya Ryota , Manabe Atsushi 
Published: June 2016

AbstractEwing sarcoma/primitive neuroectodermal tumor (ES/PNET) of the kidney is extremely rare, and is usually diagnosed after nephrectomy without neoadjuvant chemotherapy. Although ifosfamide and etoposide improve survival to a great extent in ES/PNET, the use of nephrotoxic agent, particularly ifosfamide, is a concern after nephrectomy. We describe the case of a 14‐year‐old female patient with abdominal mass who was diagnosed with ES/PNET of the right kidney after nephrectomy. Adjuvant chemotherapy including ifosfamide and etoposide were given. The estimated glomerular filtration rate decreased to 75% after the end of therapy. There was no evidence of recurrence 70 months after initial diagnosis.
Repeated fecal microbiota transplantation in a child with ulcerative colitis
Authors: Shimizu Hirotaka , Arai Katsuhiro , Abe Jun , Nakabayashi Kazuhiko , Yoshioka Takako , Hosoi Kenji , Kuroda Makoto 
Published: June 2016

AbstractWe report the case of an 11‐year‐old girl with ulcerative colitis refractory to conventional therapy, who was subsequently treated successfully with repeated fecal microbiota transplantation (FMT). The patient was steroid dependent despite several infliximab treatments, and colectomy was proposed to improve quality of life. After repeated FMT, she was able to maintain remission with on minimal dose of steroid. Although her fecal microbiota was dysbiotic before FMT, it was restored to a similar pattern as the donor after repeated FMT.