bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attitudes Toward Adoption of Evidence-Based Practice Among Physical Therapists and Social Workers: A Lesson for Interprofessional Continuing Education
Authors: Gudjonsdottir Bjorg , Arnadottir Hervor A. , Gudmundsson Halldor S. , Juliusdottir Sigrun , Arnadottir Solveig A. 
Published: January 2017

Introduction:Professionals who embrace evidence-based practice (EBP) continually search for research evidence, appraise, and apply it, while interacting with each client in his/her situation. This dynamic learning process takes a substantial commitment from professionals and requires a positive attitude toward EBP. The main objective of this research was to explore the following: 1) distinct dimensions of attitudes toward adoption of EBP among physical therapists and social workers and 2) the relationship between these dimensions of attitudes and selected background characteristics of the compared professions.Methods:Cross-sectional web-based surveys were conducted in 2012 and 2013 on a population-based sample from the Icelandic Physical Therapy Association and the Icelandic Association of Social Workers. The participants were 214 physical therapists (76.3% women) and 163 social workers (92.2% women). The Evidence-Based Practice Attitude Scale (EBPAS) and its four subscales were used to survey dimensions of attitudes toward EBP. Scores on the total EBPAS range from zero to five, with a higher score indicating a more positive attitude toward EBPs. Linear regression was used to explore the relationship between the EBPAS scales and selected background variables.Results:The overall response rate was 39%. Both professions generally held positive attitudes toward adoption of EBP, with an average EBPAS total score of 3.06 (SD = 0.46). The professionals' background characteristics were independently related to at least one dimension of attitudes toward EBP. More positive attitudes were associated with being a physical therapist, a woman, in a younger age group, having a graduate degree, working with individual clients, and having at least five same-profession coworkers.Discussion:The results may be useful to design continuing education focusing on EBP. Such inventions should be targeted to professional attitudes, background, and other contextual factors.
Curvilinear Segmental Mandibular Reconstruction Utilizing Distraction Osteogenesis and Early Open Callus Manipulation
Authors: Pereira Alberto Rocha , Neves Paulo , Rosa José , Bartlett Scott 
Published: January 2017

Summary:
The authors present a new technique for reconstruction of large curvilinear mandibular defects with distraction osteogenesis and early open callus manipulation. In phase 1, transport disks are created from mandibular bone and distracted across the entire length of the defect, without the restriction from a mandible plate fixation. This allows for full-length distraction until enough regenerate is obtained to reconstruct the defect without the need for additional bone grafts. Taking advantage of the soft moldable regenerate, the second and final operative procedure allows for the manipulation, repositioning, and fixation of the transported segments in the ideal position creating perfect tridimensional form and symmetry of the mandible arch. In addition, the consolidation phase is shortened by the early removal of distractors, substantially reducing the total length of treatment. This article describes 2 clinical cases treated according to this technique, one with a 6-cm mandibular defect where a sagittal plane manipulation was performed, and the other with a 7-cm defect and axial plane manipulation. Five years postsurgery, both patients had achieved full stable reconstruction without the need for bone grafting, and had obtained good facial symmetry, with no recorded complications. This technique serves to establish bone transport as a valuable alternative to bone free flaps in the reconstruction of large curvilinear segmental mandibular defects.
Convection - Diffusion model of talking bacteria
Authors: Majumdar Sarangam , Mondal Subhoshmita 
Published: January 2017

abstractQuorum sensing is cell to cell communication process through chemical signals formally known as autoinducers. When the concentration of quorum sensing molecules reached threshold concentration bacteria are in active state or quorum state. In this article, we propose a mathematical model of quorum sensing systems and study this biological system numerically. Moreover, we compare the different numerical scheme with the batch culture ofP.aeruginosa. We observed a negative diffusion coefficient which plays an important role in the quorum sensing mechanism.
WikiGenomes: an open Web application for community consumption and curation of gene annotation data in Wikidata
Authors: Putman Tim E. , Lelong Sebastien , Burgstaller-Muehlbacher Sebastian , Waagmeester Andra , Diesh Colin , Dunn Nathan , Munoz-Torres Monica , Stupp Gregory S. , Su Andrew I. , Good Benjamin M. 
Published: January 2017

AbstractWith the advancement of genome sequencing technologies, new genomes are being sequenced daily. While these sequences are deposited in publicly available data warehouses, their functional and genomic annotations (beyond genes which are predicted automatically) mostly reside in the text of primary publications. Professional curators are hard at work extracting those annotations from the literature for the most studied organisms and depositing them in structured databases. However, the resources don’t exist to fund the comprehensive curation of the thousands of newly sequenced organisms in this manner. Here, we describe WikiGenomes (wikigenomes.org), a web application that facilitates the consumption and curation of genomic data by the entire scientific community. WikiGenomes is based on Wikidata, an openly editable knowledge graph with the goal of aggregating published knowledge into a free and open database. WikiGenomes empowers the individual genomic researcher to contribute their expertise to the curation effort and integrates the knowledge into Wikidata, enabling it to be accessed by anyone without restriction.
Experimental Zika Virus Infection in a New World Monkey Model Reproduces Key Features of the Human Disease
Authors: Chiu Charles , Bouquet Jerome , Li Tony , Yagi Shigeo , Martin Claudia Sanchez San , Tamhankar Manasi , Hodara Vida L. , Parodi Laura M. , Somasekar Sneha , Yu Guixia , Giavedoni Luis D. , Tardif Suzette , Patterson Jean 
Published: January 2017

ABSTRACTHuman infections by Zika virus (ZIKV), a mosquito-borne flavivirus, are associated with a current widespread outbreak in the Americas, and have been associated with neurological complications and adverse fetal outcomes such as microcephaly in pregnant women. A suitable non-human primate model is urgently needed. To evaluate ZIKV infectivity, pathogenesis, and persistence, we inoculated 4 marmosets with ZIKV and followed them by clinical monitoring and serial sampling of body fluids for up to 11 weeks. We found that marmosets experimentally infected with ZIKV reproduced key features of the human disease, including (1) asymptomatic infection, (2) brief period of detectable virus in serum (<1 week), (3) detection in other body fluids (urine, saliva, semen, and stool) for at least 2 weeks following acute infection, and (4) persistence in lymph nodes, but not other tissues, at 1 month post-infection. ZIKV-positive saliva and serum samples, but not urine, were found to be infectious in cell culture. By day 6 post-inoculation, most marmosets exhibited detectable neutralizing antibody responses concurrent with activation of NK cell and B cell subsets and an increase in circulating cytokines associated with type II interferon signaling, Transcriptome profiling revealed enrichment of immune responses to active viral infection, with up-regulation of both type I and II interferon signaling pathways, anduncovered potential host biomarkers. These results suggest that a New World monkey model of acute ZIKV infection mimics the human disease, and is likely to be useful for testing of drug and vaccine candidates.
Gut microbiota and resistome dynamics in intensive care patients receiving selective digestive tract decontamination
Authors: Buelow Elena , González Teresita de Jesús Bello , Fuentes Susana , Piters Wouter A.A. de Steenhuijsen , Lahti Leo , Bayjanov Jumamurat R. , Majoor Eline A.M. , Braat Johanna C. , Mourik Maaike S. M. van , Oostdijk Evelien A.N. , Willems Rob J.L. , Bonten Marc. J.M. , Passel Mark W.J. van , Smidt Hauke , Schaik Willem van 
Published: January 2017

ABSTRACTBackgroundCritically ill patients hospitalized in an Intensive Care Unit (ICU) are at increased risk of acquiring potentially life-threatening infections with opportunistic pathogens. The gut microbiota of ICU patients forms an important reservoir for these infectious agents. To suppress gut colonization with opportunistic pathogens, a prophylactic antibiotic regimen, termed ‘Selective decontamination of the digestive tract’ (SDD), may be used. SDD has previously been shown to improve clinical outcome in ICU patients, but the impact of ICU hospitalization and SDD on the gut microbiota remains largely unknown. Here, we characterize the composition of the gut microbiota and its antimicrobial resistance genes (‘the resistome’) of ICU patients during SDD.ResultsDuring ICU-stay, 30 fecal samples of ten patients were collected. Additionally, feces were collected from five of these patients after transfer to a medium-care ward and cessation of SDD. As a control group, feces from ten healthy subjects were collected twice, with a one-year interval. Gut microbiota and resistome composition were determined using 16S rRNA phylogenetic profiling and nanolitre-scale quantitative PCRs.The microbiota of the ICU patients differed from the microbiota of healthy subjects and was characterized by low microbial diversity, decreased levels ofE. coliand of anaerobic Gram-positive, butyrate-producing bacteria of theClostridiumclusters IV and XIVa, and an increased abundance of Bacteroidetes and enterococci. Four resistance genes (aac(6′)-Ii,ermC,qacA,tetQ), providing resistance to aminoglycosides, macrolides, disinfectants and tetracyclines respectively, were significantly more abundant among ICU patients than in healthy subjects, while a chloramphenicol resistance gene (catA) and a tetracycline resistance gene (tetW) were more abundant in healthy subjects.ConclusionsThe microbiota and resistome of ICU patients and healthy subjects were noticeably different, but importantly, levels ofE. coliremained low during ICU hospitalization, presumably due to SDD therapy. Selection for four antibiotic resistance genes was observed, but none of these are of particular concern as they do not contribute to clinically relevant resistance. Our data support the ecological safety of SDD, at least in settings with low levels of circulating antibiotic resistance.
Alternative Methods for Mitochondrial Transplantation: Efficiency of Unpackaged and Lipid-Packaged Preparations
Authors: McPhie DL , Sargent LW , Babb SM , Ben-Shachar D , Cataldo AM , Cohen BM 
Published: January 2017

AbstractMitochondrial transplantation is currently being explored as a means to repair and restore proper organelle function in a variety of inherited and acquired disorders of energy metabolism. The optimal preparation and application of donor mitochondria is unknown, but most studiesin vivohave used injection techniques or, for tissue studies, unpackaged mitochondria (organelles isolated and suspended in buffer) in transplant experiments. Packaging in lipid rafts can increase recipient cell uptake of some compounds and objects. We present the first data comparing recipient cell uptake of unpackaged mitochondria to recipient cell uptake of mitochondria packaged in cell membrane lipids. Mitochondria and membranes were prepared from autologous cells and applied to cells (fibroblasts) in culture. Both unpackaged and lipid-packaged mitochondria were taken into recipient cells and the donor mitochondria showed evidence, in each case, of retained functionality and the abilityto merge with the recipient mitochondrial matrix. However, lipid packaging appeared to enhance the uptake of functional mitochondria. Current studies of mitochondrial transplantation in animal models might fruitfully explore the utility and efficacy of lipid-packaged mitochondria in transplant experiments.
High density genome scan for selection signatures in French sheep reveals allelic heterogeneity and introgression at adaptive loci
Authors: Rochus Christina Marie , Tortereau Flavie , Plisson-Petit Florence , Restoux Gwendal , Moreno Carole , Tosser-Klopp Gwenola , Servin Bertrand 
Published: January 2017

AbstractSheep was one of the first domesticated livestock species in the Anatolia region of contemporary Iran and eventually spread world-wide. Previous studies have shown that French sheep populations likely harbour a large part of European domesticated sheep diversity in a relatively small geographical region, offering a powerful model for the study of adaptation. We studied the diversity of 27 French sheep populations by genotyping 542 individuals for more than 500 000 SNPs. We found that French sheep breeds were divided into two main groups, corresponding to northern and southern origins and additionally we identified admixture events between northern and southern populations. The genetic diversity of domesticated animals results from adaptation of populations to constraints imposed by farmers and environmental conditions. We identified 126 genomic regions likely affected by selection. In many cases, we found evidence for parallel selection events in different genetic backgrounds, most likely for different mutations. Some of these regions harbour genes potentially involved in morphological traits (SOCS2,NCAPG/LCORL,MSRB3), coat colour (MC1R) and adaptation to environmental conditions (ADAMTS9). Closer inspection of two of these regions clarified their evolutionary history: at theLCORL/NCAPGlocus we found evidence for introgression of an adaptive allele from a southern population into northern populations and by resequencingMC1Rin some breeds we confirmed different mutations in this gene are responsible for the same phenotypic trait. Our study illustrates how dense genetic data in multiple populations allows the deciphering of evolutionary history of populations and of their adaptive mutations.
Decoding the categorization of visual motion with magnetoencephalography
Authors: Bekhti Yousra , Gramfort Alexandre , Zilber Nicolas , Wassenhove Virginie van 
Published: January 2017

ABSTRACTBrain decoding techniques are particularly efficient at deciphering weak and distributed neural patterns. Brain decoding has primarily been used in cognitive neurosciences to predict differences between pairs of stimuli (e.g. facesvs.houses), but how distinct brain/perceptual states can be decoded following the presentation of continuous sensory stimuli is unclear. Here, we developed a novel approach to decode brain activity recorded with magnetoencephalography while participants discriminated the coherence of two intermingled clouds of dots. Seven levels of visual motion coherence were tested and participants reported the colour of the most coherent cloud. The decoding approach was formulated as a ranked-classification problem, in which the model was evaluated by its capacity to predict the order of a pair of trials, each tested with two distinct visual motion coherence levels. Two brain states were decoded as a function of the degree of visual motion coherence. Importantly, perceptual motion coherence thresholds were found to match the decoder boundaries in a fully data-driven way. The algorithm revealed the earliest categorization in hMT+, followed by V1/V2, IPS, and vlPFC.
Supply chain practices and organizational performance
Authors: Gorane Shrikant , Kant Ravi 
Published: January 2017

Purpose
The purpose of this paper is to empirically test a framework which identifies the relationships between various supply chain practices (SCPs) and organizational performance (operational performance (OP), customer satisfaction, and financial performance) in the context of Indian manufacturing organizations.

Design/methodology/approach
From the literature, ten SCPs are selected which finally influences the organizational performance. In order to understand the interactions between SCPs and organizational performance, this paper grouped the ten SCPs into four constructs namely: information and communication technology, supply chain (SC) integration, operational responsiveness, and closed loop green practices. Three levels of firm performance are also examined, including OP, customer satisfaction, and financial performance. The paper-based and web-based survey yielded 292 responses from the Indian manufacturing organizations. The data collected were put through rigorous statistical analysis to test for the content, construct, and criterion-related validity, as well as reliability analyses. Further a structural equation model was developed to test the relationships between SCPs and organizational performance.

Findings
The finding suggests that a successful SCPs implementation not only improves the OP, but also enhances customer satisfaction and financial performance. In addition, higher financial performance is also attributable to better customer value resulting from the achievement of better customer satisfaction.

Research limitations/implications
SCPs are complex constructs. While this study shows the effect of broadly accepted SCPs on organizational performance, not all possible practices are covered in this study. Again the study can be further extended to sector specific so that the results can be further refined.

Practical implications
This is one of the few studies which attempts to investigate whether there is any relationship exits between SCPs and organizational performance. The finding will help decision makers in the organization to know the importance of SCPs and how SCPs influence the organizational performance. Second, this study has developed and validated a multi-dimensional construct of SCPs, which can assist decision makers of Indian organizations to evaluate the competence of their current status of SCPs in the organization.

Originality/value
As per the knowledge of the authors, this is the first kind of study which empirically investigated the relationships between SCPs and organizational performance in the context of Indian manufacturing organizations.
Research on the dynamic characteristics of a 3-DOF parallel tool head
Authors: Wang Dong , Wu Jun , Wang Liping , Liu Yuzhe , Yu Guang 
Published: January 2017

Purpose
The purpose of this paper is to describe and evaluate the time-varying and coupling dynamic characteristics of a 3-DOF parallel tool head.

Design/methodology/approach
From the view of control, a new dynamic index of a 3-DOF parallel tool head is proposed based on the dynamic model in the joint space. This index can reflect the time-varying and coupling dynamic characteristics which are the main characteristics of the parallel mechanisms, and its distribution in the whole workspace is also given. Through comparison of the dynamic load (driving current) of each driving shaft, a series of experiments is designed and carried out on a prototype to validate the effectiveness of the dynamic analysis. The tracking error of each driving shaft has also been taken into consideration.

Findings
The simulations of the index have the same variation law with the experimental results. The dynamic load of the driving shaft becomes larger with the increase of the dynamic index, and the dynamic performance becomes worse at the same time.

Originality/value
The main dynamic characteristics of the 3-DOF parallel tool head can be described and evaluated through this work.
The antecedents of creative article diffusion on blogs
Authors: Cheng Hsiu-Hua 
Published: January 2017

PurposeBloggers often create digital content. Diffusion of the creative articles can make many bloggers or readers visit blog platforms. Restated, diffusion of the creative articles can assist blog service providers (BSPs) to retain bloggers and attract new bloggers. Thus, the research is conducted on creative article diffusion on blogs based on innovation diffusion theory and social network theory. The paper aims to discuss this issue.Design/methodology/approachIn this study, an information system was used to collect 250 creative articles and social network data of these creative articles. Validity of the specific study hypotheses is tested by using multi-regression analysis.FindingsAnalytical results indicate both observability and network density positively affect creative article diffusion, and ties-strength negatively affects creative article diffusion.Research limitations/implicationsSince the interpersonal interactive mechanism of blogs differs from that of social network websites, bloggers establish different social networks which may influence innovation diffusion. However, different websites may have different interpersonal interactive mechanisms. Therefore, the results of this study should not be over-generalized.Practical implicationsFor diffusing information, BSPs may focus on blog articles with trackback rate below 10 percent among the friends-bloggers network and advertise these articles to make their trackback rate increase to 10-20 percent to reach the self-sustaining status. This strategy ensures the largest payoff from creative article diffusion.Originality/valueThis study contributes to the knowledge of social network and innovation diffusion on blog website and develops a model explaining how antecedents influence creative article diffusion.
Real-time profiling of reflow process in VPS chamber
Authors: Livovsky Lubomir , Pietrikova Alena 
Published: January 2017

Purpose
This paper aims to present a new method of real-time monitoring of thermal profiles applied in vapour phase soldering (VPS) reflow processes. The thermal profile setting is a significant variable that affects the quality of joints. The method allows rapid achievement of a required thermal profile based on software control that brings new efficiency to the reflow process and enhanced joint quality, especially for power electronics.

Design/methodology/approach
A real-time monitoring system based on computerized heat control was realized in a newly developed laboratory VPS chamber using a proportional integral derivation controller within the soldering process. The principle lies in the strictly accurate monitoring of the real defined reflow profile as a reference.

Findings
Very accurate maintenance of the required reflow profile temperature was achieved with high accuracy (± 2°C). The new method of monitoring and control of the reflow real-time profiling was verified at various maximal reflow temperatures (230°C, 240°C and 260°C). The method is feasible for reflowing three-dimensional (3D) power modules that use various types of solders. The real-time monitoring system based on computerised heat control helped to achieve various heights of vapour zone.

Originality/value
The paper describes construction of a newly developed laboratory-scale VPS chamber, including novel real-time profiling of the reflow process based on intelligent continuously measured temperatures at various horizontal positions. Real-time profiling in the laboratory VPS chamber allowed reflow soldering on 3D power modules (of greater dimensions) by applying various flux-less solder materials.