bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liver-derived human mesenchymal stem cells: a novel therapeutic source for liver diseases
Authors: Wang Yini , Yu Xiaopeng , Chen Ermei , Li Lanuan 
Published: May 2016

AbstractMesenchymal stem cells (MSCs) represent an attractive cell type for research and therapy due to their ability to proliferate, differentiate, modulate immune reactions, and secrete trophic factors. MSCs exist in a multitude of tissues, including bone marrow, umbilical cord, and adipose tissues. Moreover, MSCs have recently been isolated from the liver. Compared with other MSC types, liver-derived human MSCs (LHMSCs) possess general morphologies, immune functions, and differentiation capacities. Interestingly, LHMCSs produce higher levels of pro-angiogenic, anti-inflammatory, and anti-apoptotic cytokines than those of bone marrow-derived MSCs. Thus, these cells may be a promising therapeutic source for liver diseases. This paper summarizes the biological characteristics of LHMSCs and their potential benefits and risks for the treatment of liver diseases.
Application of fractal algorithms of coastline echo’s generation on marine radar simulator
Authors: Ji Shuguang , Zhang Zhang , Yang Hongbiao , Liu Dan , Sawhney Rapinder 
Published: May 2016

AbstractBackgroundMarine radar simulator is a useful approach endorsed by International Maritime Organization (IMO) to train the seafarers on how to operate marine radar equipment and use marine radar equipment for positioning and collision avoidance in laboratory. To fulfill all of the marine radar simulator training requirements, a high performance simulator is necessary. However, imperfections with currently available marine radar simulators require simulator developers to make improvements.Case descriptionIn this study, improved fractal algorithms (random Koch curve, fractional Brownian motion, and Weierstrass-Mandelbrot function) are applied to generate natural-looking radar echoes on a marine radar simulator.Discussion and evaluationFrom the results of the simulations, we can observe that the structures of the coastline echoes generated by improved fractal algorithms, especially by fractional Brownian motion algorithm, outperform the echoes generated by conventional method in representing a natural coastline feature.ConclusionsBased on evaluations from a panel of experienced mariners, we conclude that the coastline echoes simulated by fractal algorithms better represent a natural coastline feature than those generated by conventional methods.
Simplified Graded Baseline Symptom Assessment in Patients With Lung Cancer Undergoing First-Line Chemotherapy: Correlations and Prognostic Role in a Resource-Constrained Setting
Authors: Singh Potsangbam Sarat , Aggarwal Ashutosh Nath , Behera Digambar , Kapoor Rakesh , Singh Navneet 
Published: May 2016

Purpose There are limited data from developing countries on graded baseline symptom (BS) assessment in lung cancer. This prospective study aimed to assess the prognostic role of BS and correlation of BS with comorbidity, demographic, and investigation profiles in a cohort of 238 patients with lung cancer undergoing first-line chemotherapy over a 15-month period. Methods The Medical Research Council (MRC) scale was used to assess dyspnea, whereas the visual analog scale (VAS; score of 1 to 10) was used to assess anorexia, fatigue, chest pain, and cough. Weight loss (WL) was noted as percentage of pre-illness baseline. All patients received histology-guided platinum doublet chemotherapy. Outcomes assessed were overall survival (OS) and radiologic responses by RECIST. Results Significant correlations (Spearman ρ) were noted for fatigue and anorexia with all other BSs. Dyspnea differed significantly among groups on the basis of either the simplified comorbidity score or Charlson comorbidity index. Median OS was 287 days (95% CI, 232 to 342 days). OS was significantly higher for anorexia VAS score less than 4 (388 v 229 days for VAS score ≥ 4), fatigue VAS score less than 3 (388 v 213 days for VAS score ≥ 3), WL less than 5% (410 v 259 days for WL ≥ 5%), and MRC dyspnea grade less than 3 (377 v 187 days for MRC grade ≥ 3). On univariable Cox proportional hazards analysis, worse OS was noted for all BSs, stage, and performance status, but on multivariable analysis, only fatigue (hazard ratio [HR], 1.21), Eastern Cooperative Oncology Group performance status ≥ 2 (HR, 1.57), and stage IV disease (HR, 1.61) were significant. Nonresponders (stable disease and progressive disease [PD]) had a higher percentage of WL and higher mean VAS scores for cough, chest pain, anorexia, and fatigue. On multivariable logistic regression analysis, PD was associated with fatigue and percentage of WL. Conclusion BSs are prognostic for patients with lung cancer on first-line chemotherapy. Fatigue is prognostic for worse OS and PD. Comorbidity and investigation profiles do not correlate with either OS or response rates.
Health professionals' perceptions of inappropriate use of A&E services
Authors: Chapman Beatrice , Turnbull Triece 
Published: May 2016

Objective: The aim of this study was to investigate health professionals' perceptions of the inappropriate use of accident and emergency (A&E) services. Method: Qualitative methods were used to interview nine hospital staff as part of this exploratory study. Results: Seven main themes emerged from the data: convenience; lack of patient knowledge and help-seeking behaviour; lack of awareness of services; lack of knowledge of local services among health and social-care professionals; long-term conditions; parents with small children; and the local Nepalese community. Conclusion: Further research is needed to understand what drives service-users' behaviour to use A&E services inappropriately for non-urgent treatment.
Elevated levels of matrix metalloproteinases and chronic wound healing: an updated review of clinical evidence
Authors: Lazaro J.L. , Izzo V. , Meaume S. , Davies A.H. , Lobmann R. , Uccioli L. 
Published: May 2016

Objective:In the past 20 years, research and clinical trials on the healing process of chronic wounds have highlighted the key role of the family of enzymes called matrix metalloproteinases (MMPs). If a strong correlation between the course of healing of chronic wounds and the levels of a biological marker can be demonstrated, then it may be possible to: i) identify the best marker threshold to predict the clinical evolution of the pathology; and ii) if causality has been found between the marker and pathology, to improve the healing outcome, to change the marker level.Method:The databases Medline and Embase were searched to identify clinical trials pertaining to the assessment of MMPs in chronic wounds with the following keywords ‘metalloproteinase’ or ‘metalloprotease’ and ‘wound healing’. Clinical trials were considered for inclusion if they enrolled patients with cutaneous chronic wounds and were published in English. More than 50 clinical trials, consensus documents and guidelines were assessed for this review.Results:MMPs play key roles in the wound healing process, and excessive expression and activation of some of these enzymes is seen in chronic cutaneous wounds where healing is delayed. Levels of MMPs are affected by a number of factors, including patient and wound characteristics.Conclusion:Levels of MMPs can be used to indicate the prognosis of chronic wounds and protease modulating treatments used to improve healing rates.Declaration of interest:The authors report no conflicts of interest in this work.
Solution of The Schrödinger Equation for Trigonometric Scarf Plus Poschl-Teller Non-Central Potential Using Supersymmetry Quantum Mechanics
Authors: C Cari , S Suparmi , Saregar Antomi 
Published: May 2016

<span>In this paper, we show that the exact energy eigenvalues and eigen functions of the Schrödinger <span>equation for charged particles moving in certain class of noncentral potentials can be easily <span>calculated analytically in a simple and elegant manner by using Supersymmetric method <span>(SUSYQM). We discuss the trigonometric Scarf plus Poschl-Teller systems. Then, by operating <span>the lowering operator we get the ground state wave function, and the excited state wave functions <span>are obtained by operating raising operator repeatedly. The energy eigenvalue is expressed in the <span>closed form obtained using the shape invariant properties. The results are in exact agreement with <span>other methods.</span></span></span></span></span></span></span><br /></span>
Curved Dyonic Domain Walls in Four Dimensions
Authors: Gunara Bobby Eka 
Published: May 2016

<span>In this short paper we show the existence of solitonic solutions of four dimensional ungauged N=1 <span>supergravity coupled to arbitrary vector and chiral multiplets whose Ricci scalar curvature is constant. <span>The Ricci scalar of spacetimes indeed depends on the <span><em>σ</em><span>-model, namely the complex scalars and their first <span>derivative. Then, we give two explicit models, namely static domain walls and static spherical symmetric <span>black holes which are related to our previous works.</span></span></span></span><br /></span></span></span>
Identification of Sandstone Reservoir Saturated by Oil Using Low Frequency Analysis with base on CWT and AVO Analysis
Authors: S Sudarmaji , Nurcahya Budi Eka 
Published: May 2016

<span>Identification of sandstone resevoir saturated by oil has been conducted by mean low <span>frequency and amplitude versus offset (AVO) analysis. Low Frequency analysis was has been <span>conducted among 3D and 2D seismic data of PSTM gather using continuose wavelet transform <span>(CWT) around 15hz. Low frequency analysis was done by calculating attribute gradient time <span>frequency of instantaneous amplitude using continuous wavelet transform (CWT) around <span>15hz for detecting the existing diffusive wave from reflection seismic. Diffusive wave is a <span>wave that appears due to fluid movement in porous rock, especially fluid of hydrocarbon with <span>certain viscosity and permeability. While amplitude versus offset (AVO) analysis was done <span>for detecting the impedance character of sandstone reservoir that related to porous rock. <span>Amplitude versus offset (AVO) analysis was done by calculating gradient*intercept and <span>observing the curve of wave reflectivity as a function of offset. The positive value of <span>gradient*intercept and curve of reflectivity as a function of offset could be identified as AVO<br /><span>class III and correlated to sandstone reservoir with low impedance and good porosity.</span></span></span></span></span></span></span></span></span></span></span></span><br /></span>
Equivariant basic cohomology of Riemannian foliations
Authors: Goertsches Oliver , Töben Dirk 
Published: May 2016

Abstract
The basic cohomology of a complete Riemannian foliation with all leaves closed is the cohomology of the leaf space. In this paper we introduce various methods to compute the basic cohomology in the presence of both closed and non-closed leaves in the simply-connected case (or more generally for Killing foliations): We show that the total basic Betti number of the union C of the closed leaves is smaller than or equal to the total basic Betti number of the foliated manifold, and we give sufficient conditions for equality. If there is a basic Morse–Bott function with critical set equal to C, we can compute the basic cohomology explicitly. Another case in which the basic cohomology can be determined is if the space of leaf closures is a simple, convex polytope.
Our results are based on Molino’s observation that the existence of non-closed leaves yields a distinguished transverse action on the foliated manifold with fixed point set C. We introduce equivariant basic cohomology of transverse actions in analogy to equivariant cohomology of Lie group actions enabling us to transfer many results from the theory of Lie group actions to Riemannian foliations. The prominent role of the fixed point set in the theory of torus actions explains the relevance of the set C in the basic setting.
Haketia in Morocco. Or, the story of the decline of an idiom
Authors: Bürki Yvette 
Published: May 2016

AbstractThis contribution takes a diachronic look at the political, social, cultural and economic reasons behind the decline of Haketia, which has become one of the most symbolic icons in the collective memory of the Hispano-Moroccan Sephardic Jews in their new settlements. The article has three parts: it opens with a general section that introduces the concept of
Fa d’Ambô: from past to present
Authors: Hagemeijer Tjerk , Zamora Armando 
Published: May 2016

AbstractThis article addresses the historical and sociolinguistic evolution of Fa d’Ambô, a Portuguese-related creole language spoken originally on the small island of Annobón in Equatorial Guinea. It will be shown that Fa d’Ambô and the three creole languages spoken on the islands of São Tomé and Príncipe (Santome, Angolar and Principense) descend from a single contact language that arose on the island of São Tomé and branched in the sixteenth century. After its permanent settlement in the second half of the sixteenth century, Annobón became strongly isolated until the twentieth century. Due to intense migration from Annobón to Equatorial Guinea’s multilingual capital Malabo over the last decades, Fa d’Ambô’s speech community has not only become divided but also more exposed to other languages, in particular to English-based creole Pichi, the capital’s lingua franca. Given the small size of the Fa d’Ambô speech community (approx. 5,000 speakers), it will be argued that these factors, in addition to the lack of government support for the country’s minority languages, pose an increasing threat to the survival of the language.
“The only language we speak really well”: the English creoles of Equatorial Guinea and West Africa at the intersection of language ideologies and language policies
Authors: Yakpo Kofi 
Published: May 2016

AbstractThis article explores the nexus between language policies and language ideologies in Equatorial Guinea and West Africa. By analyzing spoken and written discourses in Spanish and Pichi, I identify a set of ideas and beliefs about Pichi and the semiotic processes by which they have emerged. The comparison of Pichi with Krio, Nigerian Pidgin, Cameroon Pidgin and Ghanaian Pidgin English shows that Pichi is the most disadvantaged of the West African English-lexicon creoles with respect to a number of sociolinguistic characteristics. I argue that linguistic ideologies about Pichi have contributed significantly to disregarding language policy options for elevating the status and extending the uses of Pichi in Equatorial Guinea. Pichi is nevertheless expected to expand its social functions by gradually conquering additional domains of use as has been the case with the other English creoles of West Africa.
Cervical pessary for the prevention of preterm birth: is it of any use?
Authors: Falcão Vera , Melo Catarina , Matias Alexandra , Montenegro Nuno 
Published: May 2016

Abstract
Preterm birth (PTB) represents a heavy burden in modern obstetrics as it is a major cause of perinatal morbidity and mortality. After the introduction of transvaginal sonography (TVS) screening, secondary prevention of PTB has been re-evaluated on the basis of pre-existing cervical length (CL) and meanwhile the cervical pessary has become an object of increasing interest. This device consists of a silicone cone acting mechanically, that can be easily placed or removed, but whose efficacy is still controversial. Therefore, this study aims to review the most recent evidence regarding its efficacy for prevention of PTB, together with the correct position, the evidence regarding the mechanism of action, the exclusion criteria for pessary placement and the reasons for precocious removal. Overall, it is well tolerated and there are no reports on severe associated side effects. Finally, we discuss published data regarding cervical pessary efficacy. Although results are still conflicting, it seems however to be an effective method for preventing PTB, both in singleton and multiple pregnancies, but further evidence is needed.
Improvement in detecting bacterial infection in lower respiratory tract infections using the Intensive Care Infection Score (ICIS)
Authors: Kaeslin Martha , Brunner Saskia , Raths Janine , Huber Andreas 
Published: May 2016

Abstract

Background: Immediate treatment of lower respiratory tract infections (LRTI) caused by bacteria is important to reduce pneumonia and other complications such as systemic inflammatory response syndrome and sepsis. Nowadays procalcitonin (PCT) is the gold standard to differentiate between bacterial and non-bacterial infections in LRTI. The aim of this study was to evaluate if the new Intensive Care Infection Score (ICIS) which is a combination of various cellular measurements made on hematology analyzers could be a potential method to differentiate between bacterial and non-bacterial infections in LRTI.

Methods: The ICIS is composed of five blood-cell derived parameters characterizing the early innate immune response; (1) mean fluorescence intensity of mature (segmented) neutrophils; (2) the difference in hemoglobin concentration between newly formed red blood cells and the mature ones; (3) absolute number of segmented neutrophils; (4) absolute count of antibody secreting lymphocytes and (5) absolute count of number of granulocytes.

Results: The discriminative power of ICIS to differentiate between patients with LRTI of bacterial and non-bacterial origin is as good or even better as the commonly used infection biomarkers PCT, CRP and IL-6.

Conclusions: Beside PCT, CRP and IL-6, ICIS could be used as infection marker in LRTI.
Crystal structure of poly-[(μ-1,4-bis(2-ethylbenzimidazol-1-ylmethyl)benzene-κ2
N:N′)-bis(μ4-2,2′-(1,3-phenylene)diacetate-κ4
O:O′:O′′:O′′′)dizinc(II)], C44H38N4O8Zn2
Authors: Xu Chunying , Liu Lu , Xinhua Lou , Wang Shimin 
Published: May 2016

Abstract
C44H38N4O8Zn2, triclinic, P1̅ (No. 2), a = 9.5486(19) Å, b = 10.578(2) Å, c = 11.088(2) Å, α = 75.40(3)°, β = 102.22(3)°, γ = 114.43(3)°, V = 960.0(3) Å3, Z = 1, R
gt
(F) = 0.0305, wR
ref
(F
2
) = 0.0645, T = 293(2)K.
Crystal structure of poly-[μ-1,4-bis(2-ethylbenzimidazol-1-ylmethyl)benzene-κ2
N:N′)-bis(μ3-5-hydroxyisophthalate(2–)-κ3
O,O′:O′′)dicadmium(II)] monohydrate, C64H54N8O11Cd2
Authors: Xu Chunying , Liu Lu , Lou Xinhua 
Published: May 2016

Abstract
C64H54Cd2N8O11, monoclinic, P21/c (No. 14), a = 10.314(2) Å, b = 18.290(4) Å, c = 16.516(6) Å, β = 113.91(2)°, V = 2848.3(13) Å3, Z = 2, R
gt
(F) = 0.0440, wR
ref
(F
2
) = 0.0890, T = 293(2)K.
Photo-crosslinking hyaluronan-heparin hybrid hydrogels for BMP-2 sustained delivery
Authors: He Tianqi , Wu Dan , Wang Xianglin , Rong Jianhua , Zhao Jianhao 
Published: May 2016

Abstract
A series of hyaluronan-heparin (HA-HP) hybrid hydrogels with an HP mass content from 1% to 10% were constructed by photo-crosslinking for the sustained delivery of growth factors (GFs) in soft tissue engineering. Glycidyl methacrylated HA (HAGMA) and glycidyl methacrylated HP (HPGMA) at a substitution degree of 33% and 17%, respectively, by 1H nucleic magnetic resonance (1H NMR) were synthesized and then used for gelation under ultraviolet radiation, followed by various characterizations, including elemental analysis, scanning electron microscopy (SEM), water swelling test, rheological analysis, and bone morphogenetic protein-2 (BMP-2) loading and delivery. The actual contents of HPGMA in HA-HP hydrogels were almost the same as their feeding ratios, indicative of a complete reaction by photo-crosslinking. The incorporation of HP into HA network gently influenced the morphology, water swelling property and rheological properties of hydrogels, but at 10% HP, it doubly increased the BMP-2 loading capacity to 65 ng/mg, alleviated the BMP-2 burst release to 40% within the initial 4 days and prolonged the BMP-2 sustained delivery to over 28 days. These results revealed that the long-term sustained delivery of BMP-2 from HA hydrogel could be achieved by conjugating HP into the crosslinked network with a controllable content.
Food meaning: From tasty to flavorful
Authors: Marrone Gianfranco 
Published: May 2016

AbstractConsidering as a starting point Greimas’s last work (De l’imperfection), taken into very little consideration by later semiotic research, I would like to see whether it would be possible to make, in the field of taste, the distinction that Greimas did in the visual field: between a “figurative” taste (that I should call tasty) and a “plastic” taste (that I should call flavorful). Much has been discussed about the synesthetic nature of gustatory sensoriality. But very little has been said about links and differences between an intellectualistic taste perception (i. e., recognition of figures of food through semantic grids) and a taste perception of a pure aesthetic nature, supported by the former and producing further significations that cannot be reproduced through language words. How does an aesthetic grasp of taste work, if it works at all? In order to answer this question I will briefly analyze different kinds of texts.
Under-reporting of sexually transmitted infection with chlamydia trachomatis - a revision of surveillance system is required
Authors: Kustec Tanja , Keše Darja , Klavs Irena 
Published: May 2016

Abstract

Introduction
To consider whether a revision of the national chlamydia surveillance system is needed, the objectives were to estimate the proportion of laboratory confirmed cases at the Institute of Microbiology and Immunology (IMI) not reported to the National Institute of Public Health (NIPH), and to assess the completeness of reporting for individual data items.

Methods
The dataset with information about the cases diagnosed at the IMI during 2007-2010, and the national chlamydia surveillance data at the NIPH, were linked using SOUNDEX code and the date of birth as unique identifier. The proportion of unreported cases was calculated. The proportions of records with missing data for individual variables were estimated for all reported cases during the same period. Chlamydia testing and reported rates for the period 2002-2010 were presented.

Results
Of 576 laboratory confirmed chlamydia cases at the IMI during 2007-2010, 201 were reported to the NIPH, corresponding to 65.1% of the overall underreporting (50.4% among dermatovenerologists, 90.1% among gynaecologist and 100% among other specialists). Item response was above 99% for demographic variables and from 69% to 81% for sexual behaviour variables. Higher testing rates corresponded to higher diagnosed rates.

Conclusions
Surveillance data underestimated diagnosed chlamydia infection rates. Mandatory reporting of cases by laboratories with less variables, including unique identifier, gender, date of diagnosis, and reporting physician specialty, together with numbers of tests performed (for estimating testing and positivity rates) would simplify the surveillance system and eliminate underreporting of laboratory confirmed cases, while still providing necessary information for public health policies.