bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Metal Free Synthesis of Diaryl Selenides Using SeO2 as a Selenium Source.
Authors: Kumar R. Uday , Reddy K. Harsha Vardhan , Satish G. , Swapna K. , Nageswar Y. V. D. 
Published: December 2016

AbstractA simple and environmentally benign protocol is developed for the synthesis of diarylselenium compounds from arylboronic acids and SeO2.
ChemInform Abstract: Isolation of Lingzhifuran A and Lingzhilactones D—F from Ganoderma lucidum as Specific Smad3 Phosphorylation Inhibitors and Total Synthesis of Lingzhifuran A.
Authors: Ding Wei‐Yi , Ai Jun , Wang Xin‐Long , Qiu Fayang G. , Lv Qing , Fang Ping , Hou Fan‐Fan , Yan Yong‐Ming , Cheng Yong‐Xian 
Published: December 2016

AbstractThe four new phenolic meroterpenoids, lingzhifuran A (I) and lingzhilactones D—F (II—IV), show inhibitory activities against transforming growth factor‐β1‐induced Smad3 phosphorylation.
ChemInform Abstract: Two New Ring A‐Cleaved Lanostane‐Type Triterpenoids and Four Known Steroids Isolated from Endophytic Fungus Glomerella sp. F00244.
Authors: Guo Kai , Fang Huiqin , Gui Fu , Wang Yuezhou , Xu Qinyan , Deng Xianming 
Published: December 2016

Abstractisolation, structure elucidation, antimicrobial and cytotoxic activities of two new triterpenoids, called glometenoid A (I) and glometenoid B (II), together with four known ergostane‐type steroids
ChemInform Abstract: Three New Abietane‐Type Diterpenes from the Bark of Cryptomeria japonica.
Authors: Chang Chi‐I , Chen Chien‐Chih , Wang Sheng‐Yang , Chao Che‐Yi , Chao Louis Kuoping , Chen Jih‐Jung , Ko Horng‐Huey , Chen Cheng‐Chi , Kuo Yueh‐Hsiung 
Published: December 2016

Abstractisolation and structure elucidation
ChemInform Abstract: Four New Steroidal Glycosides, Protolinckiosides A—D, from the Starfish Protoreaster lincki
Authors: Malyarenko Timofey V. , Kicha Alla A. , Kalinovsky Anatoly I. , Ivanchina Natalia V. , Popov Roman S. , Pislyagin Evgeny A. , Menchinskaya Ekaterina S. , Padmakumar Krishna Pillai , Stonik Valentin A. 
Published: December 2016

Abstract[isolation, structure elucidation and bioactivity of the title steroidal glycosides, cf.
ChemInform Abstract: Aloeverasides A and B: Two Bioactive C‐Glucosyl Chromones from Aloe vera Resin.
Authors: Rehman Najeeb Ur , Hussain Hidayat , Khiat Mohammed , Al‐Riyami Samia Ahmed , Csuk Rene , Khan Husain Yar , Abbas Ghulam , Al‐Thani Ghanim Salim , Green Ivan R. , Al‐Harrasi Ahmed 
Published: December 2016

AbstractThe title compounds (I) display good urease enzyme inhibition activities, significant growth inhibition of the breast cancer cell line MDA‐MB‐231 as well as good antioxidant activities.
ChemInform Abstract: Fissitungfines A and B, Two Novel Aporphine Related Alkaloids from Fissistigma tungfangense
Authors: Zhou Qi , Fu Yan‐Hui , Zhang Yu‐Qin , Wu Shou‐Yuan , Song Xiao‐Ping , Cao Cheng‐Ke , Xu Wei , Chen Guang‐Ying 
Published: December 2016

Abstractisolation, structure elucidation, plausible biogenetic pathway and biological activities
ChemInform Abstract: Spirobisnaphthalenes and Lactones from the Seeds of Strychnos angustiflora with Potential Antiinflammatory Activity.
Authors: Jiang Hua , Ma Shuang‐Gang , Li Yong , Liu Yun‐Bao , Li Li , Qu Jing , Yu Shi‐Shan 
Published: December 2016

AbstractThe isolation of palmarumycin SA1 (I), palmarumycin SA2 (IIa), palmarumycin SA3 (IIb), preussomerin SA1 (III), (+)‐7‐hydroxylasiodiplodin (IVa) and (+)‐7‐hydroxylasiodiplodin (IVb) is described and biological evaluation shows promising anti‐inflammatory activity of compound (I).
ChemInform Abstract: Discovery and Total Synthesis of Streptoaminals: Antimicrobial [5,5]‐Spirohemiaminals from the Combined‐Culture of Streptomyces nigrescens and Tsukamurella pulmonis.
Authors: Sugiyama Ryosuke , Nishimura Shinichi , Ozaki Taro , Asamizu Shumpei , Onaka Hiroyasu , Kakeya Hideaki 
Published: December 2016

AbstractStreptoaminal‐9n (I) and its enantiomer (II) show antibacterial activity.
ChemInform Abstract: Clindanones A and B and Cladosporols F and G, Polyketides from the Deep‐Sea Derived Fungus Cladosporium cladosporioides HDN14‐342.
Authors: Zhang Zhenzhen , He Xueqian , Liu Congcong , Che Qian , Zhu Tianjiao , Gu Qianqun , Li Dehai 
Published: December 2016

AbstractCladosporol G (I), together with another three new tetralone derivatives and three known biogenetically related polyketides, is isolated from title deep‐sea derived fungus and is shown to have the best cytotoxic activity against HeLa cells with an IC50 value of 3.9 μM.
ChemInform Abstract: Lecanicillones A—C, Three Dimeric Isomers of Spiciferone A with a Cyclobutane Ring from an Entomopathogenic Fungus Lecanicillium sp. PR‐M‐3.
Authors: Bai Jiao , et al.  
Published: December 2016

AbstractLecanicillones A—C (I—III) are isolated from an entomopathogenic fungus Lecanicillium sp.
ChemInform Abstract: Enhanced Optical and Electrical Properties of Polymer‐Assisted All‐Inorganic Perovskites for Light‐Emitting Diodes.
Authors: Ma Biwu , et al.  
Published: December 2016

AbstractCsPbBr3 perovskite thin films are prepared by spin coating of a DMSO solution of poly(ethylene oxide) (PEO) and CsPbBr3 (molar ratios of 0.065—0.259:1) followed by annealing (70 °C, 5 min).
ChemInform Abstract: Aniline‐Terephthalaldehyde Resin p‐toluenesulfonate (ATRT) as a Highly Efficient and Reusable Catalyst for Alcoholysis, Hydrolysis, and Acetolysis of Epoxides
Authors: Tanemura Kiyoshi , Suzuki Tsuneo 
Published: December 2016

AbstractReview: 38 refs.
ChemInform Abstract: Bicyclic Aziridinium Ions in Azaheterocyclic Chemistry ‐ Preparation and Synthetic Application of 1‐Azoniabicyclo[n.1.0]alkanes
Authors: Dolfen Jeroen , Yadav Nagendra Nath , De Kimpe Norbert , D'hooghe Matthias , Ha Hyun‐Joon 
Published: December 2016

AbstractReview: [56 refs.
ChemInform Abstract: Synthesis of Ciprofloxacin‐Based Compounds: A Review
Authors: Akhtar Rabia , Yousaf Muhammad , Naqvi Syed Ali Raza , Irfan Muhammad , Zahoor Ameer Fawad , Hussain Abdullah Ijaz , Chatha Shahzad Ali Shahid 
Published: December 2016

AbstractReview: 71 refs.
Numerical investigation of two phase flow in micromodel porous media: Effects of wettability, heterogeneity, and viscosity
Authors: Maaref Sepideh , Rokhforouz Mohammad‐Reza , Ayatollahi Shahab 
Published: December 2016

AbstractThe aim of the present work is to assess the effects of wettability, heterogeneity, and viscosity differences on water‐oil displacement process in micromodel porous media through numerical modelling. The two‐phase flow was simulated by Cahn‐Hilliard phase field method (PFM) using a finite element package. The micromodel was initially saturated with oil (wetting phase) and oil was produced through invasion of the displacing phase into the matrix. The computed oil and water saturations were in good agreement with those obtained by the visual flooding experiment. Using the validated model, sensitivity analysis was performed to investigate the effects of different wettability states, heterogeneity, and viscosity on the displacement process. The obtained results showed that the final oil saturation of the homogeneous pattern is 0.37 which is 13 % less than that of the heterogeneous one. For the highly oil‐wet medium (), the capillary forces prevented water to invade more pore bodies and resulted in 0.62 ultimate oil saturation; however, the final oil saturation in the neutral wet () was ∼0.5. Increasing the viscosity of displacing agent formed lower channelling and fingering which led to higher oil recovery due to the favourable mobility ratio. The present study demonstrates that PFM can be a reliable approach to capture micro‐ and macro‐scale mechanisms in the simulation of immiscible two‐phase flow in micromodel porous media with a reasonable computational time.
Verification of sound insulation in residential building – the new DIN 4109 / Nachweis des Schallschutzes im Wohnungsbau – die neue DIN 4109
Authors: Meier Andreas 
Published: December 2016

AbstractThe central sound insulation standard for building in Germany, DIN 4109, was issued in a revised version in July 2016. The calculation procedures described in the standard can now be used to verify constructional sound insulation for masonry buildings with insulated external walls. For other building materials and construction methods, the minimum requirements can be verified, or if required the enhanced requirements. Measurements in completed buildings confirm the results and show that provided the construction materials are suitable and the specialist design is correct, good sound protection is regularly achieved.
The ecohydrological vulnerability of a large inland delta to changing regional streamflows and upstream irrigation expansion
Authors: Hassanzadeh Elmira , Elshorbagy Amin , Nazemi Ali , Jardine Timothy D. , Wheater Howard , Lindenschmidt Karl‐Erich 
Published: December 2016

AbstractFuture climate change and anthropogenic interventions can alter historical streamflow conditions and consequently degrade the health and biodiversity of freshwater ecosystems. Future ecohydrological threats, however, are difficult to quantify using the cascade of climate and hydrological models due to various uncertainties involved. This study instead uses a fully bottom‐up approach to evaluate the ecohydrological vulnerability of the Saskatchewan River Delta (SRD), the largest inland delta in North America, to changing streamflow regime and irrigation expansion. An ensemble of perturbed streamflow sequences, along with scenarios of current and expanded irrigation, was generated and fed into a regional water resource system model. Results show that the streamflow regime in the delta is more sensitive to upstream changes in annual flow volume than peak flow timing and/or irrigation expansion. The sensitivity to changes in flow volume, however, may be intensified when combined with changes in peak timing. Shifts in the upstream peak flow timing can alter the magnitude and timing of peak flow to the delta, with prime importance to aquatic biota that are adapted to historical rhythmicity in peak flows and timing. Irrigation expansion decreases the magnitude and frequency of the peak flows, alters the frequency of average and low flows, and slightly shifts the timing of the mean annual peak flow in the SRD. This can lead to isolation of lakes and wetlands from the main stream. Our results highlight the ecohydrological vulnerability of the SRD under potential changing conditions and can assist in proposing adaptation policies to protect this ecosystem.
Late quaternary speleogenesis and landscape evolution in the northern Apennine evaporite areas
Authors: Columbu Andrea , Chiarini Veronica , De Waele Jo , Drysdale Russell , Woodhead Jon , Hellstrom John , Forti Paolo 
Published: December 2016

AbstractGypsum beds host the majority of the caves in the north‐eastern flank of the Apennines, in the Emilia Romagna region (Italy). More than six hundred of these caves have been surveyed, including the longest known epigenic gypsum cave systems in the world (Spipola‐Acquafredda, ~11 km). Although this area has been intensively studied from a geological point of view, the age of the caves has never been investigated in detail. The rapid dissolution of gypsum and uplift history of the area have led to the long‐held view that speleogenesis commenced only during the last 130 000 years.Epigenic caves only form when the surface drainage system efficiently conveys water into the underground. In the study area, this was achieved after the dismantling of most of the impervious sediments covering the gypsum and the development of protovalleys and sinkholes. The time necessary for these processes can by constrained by understanding when caves were first formed.The minimum age of karst voids can be indirectly estimated by dating the infilling sediments. U–Th dating of carbonate speleothems growing in gypsum caves has been applied to 20 samples from 14 different caves from the Spipola‐Acquafredda, Monte Tondo‐Re Tiberio, Stella‐Rio Basino, Monte Mauro, and Castelnuovo systems. The results show that: (i) caves have been forming since at least ~600 kyr ago; (ii) the peak of speleogenesis was reached during relatively cold climate stages, when rivers formed terraces at the surface and aggradation caused paragenesis in the stable cave levels; (iii) ~200 000 years were necessary for the dismantling of most of the sediments covering the karstifiable gypsum and the development of a surface mature drainage network.Besides providing a significant contribution to the understanding of evaporite karst evolution in the Apennines, this study refines our knowledge on the timescale of geomorphological processes in a region affected by rapid uplifting. Copyright © 2016 John Wiley & Sons, Ltd.
PhI Catalyzed Acetoxyselenylation and Formyloxyselenylation of Alkenes
Authors: Zhang Yikun , Wu Sixue , Yan Jie 
Published: December 2016

With PhI as catalyst and mCPBA as oxidant, a novel and efficient catalytic procedure has been developed for the acetoxyselenylation and formyloxyselenylation of alkenes. In this protocol, PhI is first oxidized into hypervalent iodine intermediate, which promotes the cleavage of Se–Se bond in diselenides. The in situ generated electrophilic selenium species then reacts with alkenes, affording 2‐acetoxy‐1‐selenides and 2‐formyloxy‐1‐selenides in high regioselectivity and good yields.
Calmodulin Regulated Spectrin Associated Protein 1 mRNA is Directly Regulated by miR‐126 in Primary Human Osteoblasts
Authors: Strassburg Sandra , Nabar Nikita , Lampert Florian , Goerke Sebastian M. , Pfeifer Dietmar , Finkenzeller Günter , Stark Gerhard B. , Simunovic Filip 
Published: December 2016

ABSTRACTVascularization is essential for bone development, fracture healing, and bone tissue engineering. We have previously described that coculture of primary human osteoblasts (hOBs) and human umbilical vein endothelial cells (HUVECs) improves differentiation of both cell types. Investigating the role of microRNAs (miRNAs) in this system, we found that miR‐126 is highly upregulated in hOBs following coculturing with HUVECs. In this study we performed miR‐126 gain‐of‐function and loss‐of‐function experiments in hOBs followed by microarray analysis in order to identify targets of miR‐126. The transcript cluster IDs were sieved by applying cut‐off criteria and by selecting transcripts which were upregulated following miR‐126 downregulation and vice versa. The calmodulin regulated spectrin associated protein 1 (CAMSAP1) mRNA was confirmed to be differentially regulated by miR‐126. Using the luciferase reporter assay it was demonstrated that CAMSAP1 is directly targeted by miR‐126. In this study, we show that miR‐126 and CAMSAP1 directly interact in hOBs. This finding has potential implications for tissue engineering applications. J. Cell. Biochem. 118: 1756–1763, 2017. © 2016 Wiley Periodicals, Inc.
Decomposing and Clique‐Coloring (Diamond, Odd‐Hole)‐Free Graphs
Authors: Chudnovsky Maria , Lo Irene 
Published: December 2016

AbstractA diamond is a graph on vertices with exactly one pair of nonadjacent vertices, and an odd hole is an induced cycle of odd length greater than 3. If G and H are graphs, G is H‐free if no induced subgraph of G is isomorphic to H. A clique‐coloring of G is an assignment of colors to the vertices of G such that no inclusion‐wise maximal clique of size at least 2 is monochromatic. We show that every (diamond, odd‐hole)‐free graph is 3‐clique‐colorable, answering a question of Bacsó et al. (SIAM J Discrete Math 17(3) (2004), 361–376).
Novel porcine model of implant‐associated osteomyelitis: A comprehensive analysis of local, regional, and systemic response
Authors: Jensen Louise Kruse , Koch Janne , Dich‐Jorgensen Kirstine , Aalbæk Bent , Petersen Andreas , Fuursted Kurt , Bjarnsholt Thomas , Kragh Kasper Nørskov , Tøtterup Mikkel , Bue Mats , Hanberg Pelle , Søballe Kjeld , Heegaard Peter M.H. , Jensen Henrik Elvang 
Published: December 2016

ABSTRACTPigs are favorable experimental animals for infectious diseases in humans. However, implant‐associated osteomyelitis (IAO) models in pigs have only been evaluated using high‐inoculum infection (>108 CFU) models in 1975 and 1993. Therefore, the aim of this paper was to present a new low inoculum porcine model of human IAO based on 42 experimental pigs. The model was created by drilling an implant cavity in the tibial bone followed by insertion of a small steel implant and simultaneous inoculation of Staphylococcus aureus bacteria (n = 32) or saline (n = 10). The infected pigs were either inoculated with 104 CFU (n = 26) or 102 and 103 CFU (n = 6). All animals were euthanized 5 days after insertion of implants. Pigs receiving the high‐inoculum infections showed a significantly higher volume of bone lesion, number of neutrophils around the implant, concentrations of acute phase proteins in serum, and enlargement of regional lymph nodes. A positive correlation was present between a high number of surrounding neutrophils and high values of all other parameters. Furthermore, a threshold of 40 neutrophils per 10 high power fields for the histopathological diagnosis of high grade IAO was defined. In conclusion: This paper describes a novel low‐inoculum S. aureus porcine model of IAO which was demonstrated to be reliable, reproducible and discriminative to human IAO, and represents a requested and valuable tool in orthopedic research. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2211–2221, 2017.
Fatty acids from grain fed and grass fed beef in South Africa
Authors: Hall N. , Schönfeldt H. C. , Pretorius B. 
Published: December 2016

Regular consumption of red meat is often considered detrimental to human health due, among other factors, to a perceived unhealthy fatty acid profile. With production systems intensifying globally, grain‐fed beef from feedlots are dominating market shelves within westernized countries. Although grass fed beef is considered to be a healthier alternative due to a lower total fat content and more desirable fatty acid composition, no studies have been performed to quantify such differences in South Africa.The current study evaluated the fatty acid profile of the different beef offerings available on the market, and expressed the data per edible portion to effectively guide future dietary recommendations. Notable differences were found in the quantity and quality of different fatty acids between the different production systems. Due to the unique classification system dictating the characteristics of fresh meat the result indicated distinctive differences between South African red meat and international produce.
Tropical cyclone tracking and verification techniques for Met Office numerical weather prediction models
Authors: Heming J. T. 
Published: December 2016

ABSTRACTThe Met Office has been objectively verifying tropical cyclone (TC) forecast tracks from its global numerical weather prediction model for many years and also produces TC forecast guidance in real time from both the deterministic and ensemble configurations of the model. An essential component of these processes is a system to automatically identify TCs in the model analysis and track them in the model forecast. This paper describes the history of TC tracking in Met Office models and gives details of the current technique used both within the TC forecast verification system and in the production of real‐time forecast guidance products.
Qualitatively understanding patients' and health professionals' experiences of the BRECONDA breast reconstruction decision aid
Authors: Sherman Kerry A. , Shaw Laura‐Kate , Jørgensen Lone , Harcourt Diana , Cameron Linda , Boyages John , Elder Elisabeth , Kirk Judy , Tucker Katherine 
Published: December 2016

AbstractObjectiveWomen diagnosed with breast cancer or ductal carcinoma in situ and those with a genetic susceptibility to developing this disease face the challenging decision of whether or not to undergo breast reconstruction following mastectomy. As part of a large randomized controlled trial, this qualitative study examined women's experiences of using the Breast RECONstruction Decision Aid (BRECONDA) and health professionals' feedback regarding the impact of this resource on patients' knowledge and decision making about breast reconstruction.MethodSemistructured interviews were conducted with women who accessed the BRECONDA intervention (N = 36) and with their healthcare providers (N = 6). All interviews were transcribed verbatim and subjected to thematic analysis by 3 independent coders.ResultsParticipants reported an overall positive impression, with all interviewees endorsing this decision aid as a useful resource for women considering reconstructive surgery. Thematic analysis of patient interviews revealed 4 themes: overall impressions and aesthetics; personal relevance and utility; introducing BRECONDA; and advantages and suggested improvements. Analysis of health professionals' interviews also revealed 4 themes: need for BRECONDA, impact of BRECONDA, potential difficulties that may arise in using the decision aid, and recommending BRECONDA to patients. Patients indicated that they derived benefit from this resource at all stages of their decision‐making process, with the greatest perceived benefit being for those early in their breast reconstruction journey.ConclusionThese findings support the use of BRECONDA as an adjunct to clinical consultation and other information sources.
Comparing identified and statistically significant lipids and polar metabolites in 15‐year old serum and dried blood spot samples for longitudinal studies
Authors: Kyle Jennifer E. , Casey Cameron P. , Stratton Kelly G. , Zink Erika M. , Kim Young‐Mo , Zheng Xueyun , Monroe Matthew E. , Weitz Karl K. , Bloodsworth Kent J. , Orton Daniel J. , Ibrahim Yehia M. , Moore Ronald J. , Lee Christine G. , Pedersen Catherine , Orwoll Eric , Smith Richard D. , Burnum‐Johnson Kristin E. , Baker Erin S. 
Published: December 2016

RationaleThe use of dried blood spots (DBS) has many advantages over traditional plasma and serum samples such as the smaller blood volume required, storage at room temperature, and ability to sample in remote locations. However, understanding the robustness of different analytes in DBS samples is essential, especially in older samples collected for longitudinal studies.MethodsHere we analyzed the stability of polar metabolites and lipids in DBS samples collected in 2000‐2001 and stored at room temperature. The identified and statistically significant molecules were then compared to matched serum samples stored at –80°C to determine if the DBS samples could be effectively used in a longitudinal study following metabolic disease.ResultsA total of 400 polar metabolites and lipids were identified in the serum and DBS samples using gas chromatograph/mass spectrometry (GC/MS), liquid chromatography (LC)/MS, and LC/ion mobility spectrometry‐MS (LC/IMS‐MS). The identified polar metabolites overlapped well between the sample types, though only one statistically significant metabolite was conserved in a case‐control study of older diabetic males with low amounts of high‐density lipoproteins and high body mass indices, triacylglycerides and glucose levels when compared to non‐diabetic patients with normal levels, indicating that degradation in the DBS samples affects polar metabolite quantitation. Differences in the lipid identifications indicated that some oxidation occurs in the DBS samples. However, 36 statistically significant lipids correlated in both sample types.ConclusionsThe difference in the number of statistically significant polar metabolites and lipids indicated that the lipids did not degrade to as great of a degree as the polar metabolites in the DBS samples and lipid quantitation was still possible. Copyright © 2016 John Wiley & Sons, Ltd.