bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability of upper limb tension test 1 in normal subjects and patients with carpal tunnel syndrome
Authors: Talebi Ghadam Ali , Oskouei Ali E. , Shakori Seyed Kazem 
Published: September 2016

Background and objective: Tension tests or neurodynamic techniques assess the mobility of the peripheral nerves and provide a guide for planning and managing physiotherapy treatments of entrapment syndromes such as carpal tunnel syndrome (CTS). One of the upper limb tension tests (ULTT) is ULTT1 that evaluates the efficacy of physiotherapy treatment. It has been shown to be a valid test but its reliability has not been investigated for CTS. Therefore, it is not known if the ULTT1 helps in diagnosing CTS and assessing CTS treatments. The purpose of this study was to determine the reliability of the ULTT1 in CTS. Material and methods: In order to determine the reliability of the ULTT1, we tested 23 healthy subjects and 12 subjects with CTS on two separate test days. Outcome measure for this study was elbow extension. Results: Inter subject elbow extensions were not significantly different between the two test days. Also, the coefficient of correlation ± SEM in healthy and CTS subjects were 0.89 ± 1.23 degrees and 0.84 ± 3.67 degrees, respectively. Conclusion: From the above results, we conclude that the ULTT1 is highly reliable and can be used in diagnosis as well as the management of CTS.
OUTFLOW DETECTION IN A 70 μm DARK HIGH-MASS CORE
Authors: Feng Siyi 冯思轶 , Beuther Henrik , Zhang Qizhou , Liu Hauyu Baobab 包包 , Zhang Zhiyu 张智昱 , Wang Ke 王科 , Qiu Keping 
Published: September 2016

ABSTRACT
We present observations toward a high-mass (

), low-luminosity (

)

dark molecular core G28.34 S-A at 3.4 mm, using the IRAM 30 m telescope and the NOEMA interferometer. We report the detection of

line emission, which is spatially resolved in this source at a linear resolution of ∼0.1 pc, while the 3.4 mm continuum image does not resolve any internal sub-structures. The SiO emission exhibits two W–E oriented lobes centering on the continuum peak. Corresponding to the redshifted and blueshifted gas with velocities up to

relative to the quiescent cloud, these lobes clearly indicate the presence of a strong bipolar outflow from this

dark core, a source previously considered as one of the best candidates of “starless” core. Our SiO detection is consistent with ALMA archival data of

, whose high-velocity blueshifted gas reveals a more compact lobe spatially closer to the dust center. This outflow indicates that the central source may be in an early evolutionary stage of forming a high-mass protostar. We also find that the low-velocity components (in the range of

) have an extended, NW–SE oriented distribution. Discussing the possible accretion scenarios of the outflow-powering young stellar object, we argue that molecular line emission and the molecular outflows may provide a better indication of the accretion history of the forming young stellar object, than snapshot observations of the present bolometric luminosity. This is particularly significant for cases of episodic accretion, which may occur during the collapse of the parent molecular core.
THE PHYSICAL MECHANISM BEHIND M DWARF METALLICITY INDICATORS AND THE ROLE OF C AND O ABUNDANCES
Authors: Veyette Mark J. , Muirhead Philip S. , Mann Andrew W. , Allard France 
Published: September 2016

ABSTRACT
We present near-infrared (NIR) synthetic spectra based on PHOENIX stellar atmosphere models of typical early and mid-M dwarfs with varied C and O abundances. We apply multiple recently published methods for determining M dwarf metallicity to our models to determine the effects of C and O abundances on metallicity indicators. We find that the pseudo-continuum level is very sensitive to C/O and that all metallicity indicators show a dependence on C and O abundances, especially in lower T
eff models. In some cases, the inferred metallicity ranges over a full order of magnitude (>1 dex) when [C/Fe] and [O/Fe] are varied independently by ±0.2. We also find that [(O−C)/Fe], the difference in O and C abundances, is a better tracer of the pseudo-continuum level than C/O. Models of mid-M dwarfs with [C/Fe], [O/Fe], and [M/H] that are realistic in the context of galactic chemical evolution suggest that variation in [(O−C)/Fe] is the primary physical mechanism behind the M dwarf metallicity tracers investigated here. Empirically calibrated metallicity indicators are still valid for most nearby M dwarfs due to the tight correlation between [(O−C)/Fe] and [Fe/H] evident in spectroscopic surveys of solar neighborhood FGK stars. Variations in C and O abundances also affect the spectral energy distribution of M dwarfs. Allowing [O/Fe] to be a free parameter provides better agreement between the synthetic spectra and observed spectra of metal-rich M dwarfs. We suggest that flux-calibrated, low-resolution, NIR spectra can provide a path toward measuring C and O abundances in M dwarfs and breaking the degeneracy between C/O and [Fe/H] present in M dwarf metallicity indicators.
ASASSN-16ae: A POWERFUL WHITE-LIGHT FLARE ON AN EARLY-L DWARF
Authors: Schmidt Sarah J. , Shappee Benjamin J. , Gagné Jonathan , Stanek K. Z. , Prieto José L. , Holoien Thomas W.-S. , Kochanek C. S. , Chomiuk Laura , Dong Subo , Seibert Mark , Strader Jay 
Published: September 2016

ABSTRACT
We report the discovery and classification of SDSS J053341.43+001434.1 (SDSS0533), an early-L dwarf first discovered during a powerful ΔV < −11 magnitude flare observed as part of the ASAS-SN survey. Optical and infrared spectroscopy indicate a spectral type of L0 with strong Hα emission and a blue NIR spectral slope. Combining the photometric distance, proper motion, and radial velocity of SDSS0533 yields three-dimensional velocities of (U, V, W) = (14 ± 13, −35 ± 14, −94 ± 22) km s−1, indicating that it is most likely part of the thick disk population and probably old. The three detections of SDSS0533 obtained during the flare are consistent with a total V-band flare energy of at least 4.9 × 1033 erg (corresponding to a total thermal energy of at least E
tot > 3.7 × 1034 erg), placing it among the strongest detected M dwarf flares. The presence of this powerful flare on an old L0 dwarf may indicate that stellar-type magnetic activity persists down to the end of the main sequence and on older ML transition dwarfs.
MicroRNA-133b Regulation of Th-POK Expression and Dendritic Cell Signals Affect NKT17 Cell Differentiation in the Thymus
Authors: Di Pietro Caterina , De Giorgi Lorena , Cosorich Ilaria , Sorini Chiara , Fedeli Maya , Falcone Marika 
Published: September 2016

Abstract
NKT17 cells represent a functional subset of Vα14 invariant NKT (iNKT) cells with important effector functions in infections and autoimmune diseases. The mechanisms that drive NKT17 cell differentiation in the thymus are still largely unknown. The percentage of NKT17 cells has a high variability between murine strains due to differential thymic differentiation. For example, the NOD strain carries a high percentage and absolute numbers of NKT17 cells compared with other strains. In this study, we used the NOD mouse model to analyze what regulates NKT17 cell frequency in the thymus and peripheral lymphoid organs. In accordance with previous studies showing that the zinc finger transcription factor Th-POK is a key negative regulator of thymic NKT17 cell differentiation in the thymus, our data indicate that excessive NKT17 cell frequency in NOD mice correlates with defective Th-POK expression by thymic Vα14iNKT cells. Moreover, we found that Th-POK expression is under epigenetic regulation mediated by microRNA-133b whose expression is reduced in Vα14iNKT cells of NOD mice. We also demonstrated in a conditional knockout model of dendritic cell (DC) depletion (CD11cCreXDTA.B6 and CD11cCreRosa26DTA.NOD mice) that DCs play a crucial role in regulating Vα14iNKT cell maturation and their acquisition of an NKT17 cytokine secretion phenotype in the thymus. Overall, our data show that mechanisms regulating NKT17 cell differentiation are unique and completely different from those of Vα14iNKT cells. Specifically, we found that epigenetic regulation through microRNA-133b–regulated Th-POK expression and signals provided by DCs are fundamental for thymic NKT17 cell differentiation.
Peroxiredoxin 1 Contributes to Host Defenses against Mycobacterium tuberculosis
Authors: Matsumura Kazunori , Iwai Hiroki , Kato-Miyazawa Masako , Kirikae Fumiko , Zhao Jizi , Yanagawa Toru , Ishii Tetsuro , Miyoshi-Akiyama Tohru , Funatogawa Keiji , Kirikae Teruo 
Published: September 2016

Abstract
Peroxiredoxin (PRDX)1 is an antioxidant that detoxifies hydrogen peroxide and peroxinitrite. Compared with wild-type (WT) mice, Prdx1-deficient (Prdx1−/−) mice showed increased susceptibility to Mycobacterium tuberculosis and lower levels of IFN-γ and IFN-γ–producing CD4+ T cells in the lungs after M. tuberculosis infection. IL-12 production, c-Rel induction, and p38 MAPK activation levels were lower in Prdx1−/− than in WT bone marrow–derived macrophages (BMDMs). IFN-γ–activated Prdx1−/− BMDMs did not kill M. tubercuosis effectively. NO production levels were lower, and arginase activity and arginase 1 (Arg1) expression levels were higher, in IFN-γ–activated Prdx1−/− than in WT BMDMs after M. tuberculosis infection. An arginase inhibitor, Nω-hydroxy-nor-arginine, restored antimicrobial activity and NO production in IFN-γ–activated Prdx1−/− BMDMs after M. tuberculosis infection. These results suggest that PRDX1 contributes to host defenses against M. tuberculosis. PRDX1 positively regulates IL-12 production by inducing c-Rel and activating p38 MAPK, and it positively regulates NO production by suppressing Arg1 expression in macrophages infected with M. tuberculosis.
Anaesthetic management of a case of giant cerebral aneurysm with persistent hypoglossal artery
Authors: Bharamagoudar Prakash , Monteiro Joseph , Chelani Ratan , Goraksha Shwetal 
Published: September 2016

AbstractThe persistent hypoglossal artery is a rare carotid basilar anastomosis associated with hypoplastic or absent vertebral arteries. We report a case of clipping of a 2.5 cm size giant aneurysm just distal to the persistent hypoglossal branch, using intra-arterial balloon occlusion and adenosine induced near flow arrest method. It was an anaesthetic challenge to maintain haemodynamic and homeostatic equilibrium throughout the procedure.
On Mœglin's Parametrization of Arthur Packets for p-adic Quasisplit Sp(N) and SO(N)
Authors: Xu Bin 
Published: September 2016

AbstractWe give a survey on Moeglin's construction of representations in the Arthur packets for p-adic quasisplit symplectic and orthogonal groups.The emphasis is on comparing Moeglin's parametrization of elements in the Arthur packets with that of Arthur.
Características y propiedades de pellets de biomasa torrefaccionada de Gmelina arborea y Dipterix panamensis a diferentes tiempos
Authors: Gaitán-Álvarez Johanna , Moya Roger 
Published: September 2016

La torrefacción y peletización se han estudiado en la generación de calor a partir de residuos lignocelulósicos, para incrementar las propiedades energéticas del material. El objetivo del presente trabajo fue torrefaccionar aserrín de Gmelina arborea y Dipteryx panamensis a 200 °C en tres tiempos: 0, 15 y 20 minutos. Con las biomasas obtenidas se fabricaron pellets de 6 mm de diámetro y se evaluaron sus propiedades físicas, el poder calórico, la densidad y la propiedad mecánica de resistencia a la compresión. Ambas especies presentaron características físicas similares con respecto al diámetro (0.50 mm), longitud (21.50 mm) y porcentaje de absorción de agua (6.00 %). El poder calórico aumentó de 9,749 kJ·kg-1 en la biomasa sin torrefaccionar a 18,126 kJ·kg-1 en la biomasa torrefaccionada. Los pellets de D. panamesis presentaron mayor densidad y resistencia a la compresión que los de G. arborea. Con base en los resultados, la resistencia a la compresión del pellet disminuye cuando el tiempo de torrefacción aumenta. Existe correlación positiva entre la densidad de los pellets y la resistencia a la compresión. La especie D. panamensis presenta mejor comportamiento a la torrefacción y peletización que la madera de G. arborea.
Spring blooms in the Baltic Sea have weakened but lengthened from 2000 to 2014
Authors: Groetsch Philipp M. M. , Simis Stefan G. H. , Eleveld Marieke A. , Peters Steef W. M. 
Published: September 2016

Abstract. Phytoplankton spring bloom phenology was derived from a 15-year time series (2000–2014) of ship-of-opportunity chlorophyll a fluorescence observations collected in the Baltic Sea through the Alg@line network. Decadal trends were analysed against inter-annual variability in bloom timing and intensity, and environmental drivers (nutrient concentration, temperature, radiation level, wind speed).Spring blooms developed from the south to the north, with the first blooms peaking mid-March in the Bay of Mecklenburg and the latest bloom peaks occurring mid-April in the Gulf of Finland. Bloom duration was similar between sea areas (43 ± 2 day), except for shorter bloom duration in the Bay of Mecklenburg (36 ± 11 day). Variability in bloom timing increased towards the south. Bloom peak chlorophyll a concentrations were highest (and most variable) in the Gulf of Finland (20.2 ± 5.7 mg m−3) and the Bay of Mecklenburg (12.3 ± 5.2 mg m−3).Bloom peak chlorophyll a concentration showed a negative trend of −0.31 ± 0.10 mg m−3 yr−1. Trend-agnostic distribution-based (Weibull-type) bloom metrics showed a positive trend in bloom duration of 1.04 ± 0.20 day yr−1, which was not found with any of the threshold-based metrics. The Weibull bloom metric results were considered representative in the presence of bloom intensity trends.Bloom intensity was mainly determined by winter nutrient concentration, while bloom timing and duration co-varied with meteorological conditions. Longer blooms corresponded to higher water temperature, more intense solar radiation, and lower wind speed. It is concluded that nutrient reduction efforts led to decreasing bloom intensity, while changes in Baltic Sea environmental conditions associated with global change corresponded to a lengthening spring bloom period.
Reviewer Acknowledgements for Journal of Biology and Life Science, Vol. 7, No. 2
Authors: Lee Kelvin 
Published: September 2016

<div class="WordSection1"><p>Journal of Biology and Life Science<em> (JBLS)</em><em> </em>would like to thank the following reviewers for reviewing manuscripts from February 1, 2016 to August 1, 2016. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Many authors, regardless of whether <em>JBLS</em><em> </em>publishes their work, appreciate the helpful feedback provided by the reviewers. Macrothink Institute appreciates the following reviewers’ rigorous and conscientious efforts for this journal. Each of the reviewers listed below returned at least one review during this period.</p><p> <span style="font-size: 10px;">Abhay Anand Shukla</span></p></div><div class="WordSection2"><p>Geonyzl Lepiten Alviola</p><p>Ghulam Nabi</p><p>Hossam El-Din Mohamed Omar</p><p>Khyati hitesh shah</p><p>Naimesh Solanki</p><p>Palmiro Poltronieri</p><p>Qi Sun</p><p>Rajeshwari Valiathan</p><p>Shuchi Gupta</p><p>Waldiney Mello</p></div>
Storm op komst voor bestuurders en commissarissen in de semipublieke sector
Authors: de Ruijter B.A. 
Published: September 2016

Storm op komst voor bestuurders en commissarissen in de semipublieke sector. De Wet bestuur en toezicht rechtspersonen komt eraan!
Begin juni is het wetsvoorstel bestuur en toezicht rechtspersonen ingediend bij de Tweede Kamer. Dit wetsvoorstel beoogt de regeling voor bestuur en toezicht bij de verschillende soorten rechtspersonen aan te vullen en te verduidelijken. Dit zorgt vooral voor een aanscherping van het wettelijk kader bij de niet-commerciële vereniging en de stichting. Dus semipublieke sector: opgelet!
Aberrant Transforming Growth Factor-β Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia
Authors: Wang Long , Xie Liang , Tintani Francis , Xie Hui , Li Changjun , Cui Zhuang , Wan Mei , Zu Xiongbing , Qi Lin , Cao Xu 
Published: September 2016

Abstract
Benign prostatic hyperplasia (BPH) is the overgrowth of prostate tissues with high prevalence in older men. BPH pathogenesis is not completely understood, but it is believed to be a result of de novo overgrowth of prostatic stroma. In this study, we show that aberrant activation of transforming growth factor-β (TGF-β) mobilizes mesenchymal/stromal stem cells (MSCs) in circulating blood, which are recruited for the prostatic stromal hyperplasia. Elevated levels of active TGF-β were observed in both a phenylephrine-induced prostatic hyperplasia mouse model and human BPH tissues. Nestin lineage tracing revealed that 39.6% ± 6.3% of fibroblasts and 73.3% ± 4.2% smooth muscle cells were derived from nestin+ cells in Nestin-Cre, Rosa26-YFPflox/+mice. Nestin+ MSCs were increased in the prostatic hyperplasia mice. Our parabiosis experiment demonstrate that nestin+ MSCs were mobilized and recruited to the prostatic stroma of wild-type mice and gave rise to the fibroblasts. Moreover, injection of a TGF-β neutralizing antibody (1D11) inhibits mobilization of MSCs, their recruitment to the prostatic stroma and hyperplasia. Importantly, knockout of TβRII in nestin+ cell lineage ameliorated stromal hyperplasia. Thus, elevated levels of TGF-β-induced mobilization and recruitment of MSCs to the reactive stroma resulting in overgrowth of prostate tissues in BPH and, thus, inhibition of TGF-β activity could be a potential therapy for BPH.
Neural Progenitor-Like Cells Induced from Human Gingiva-Derived Mesenchymal Stem Cells Regulate Myelination of Schwann Cells in Rat Sciatic Nerve Regeneration
Authors: Zhang Qunzhou , Nguyen Phuong , Xu Qilin , Park Wonse , Lee Sumin , Furuhashi Akihiro , Le Anh D. 
Published: September 2016

Abstract
Regeneration of peripheral nerve injury remains a major clinical challenge. Recently, mesenchymal stem cells (MSCs) have been considered as potential candidates for peripheral nerve regeneration; however, the underlying mechanisms remain elusive. Here, we show that human gingiva-derived MSCs (GMSCs) could be directly induced into multipotent NPCs (iNPCs) under minimally manipulated conditions without the introduction of exogenous genes. Using a crush-injury model of rat sciatic nerve, we demonstrate that GMSCs transplanted to the injury site could differentiate into neuronal cells, whereas iNPCs could differentiate into both neuronal and Schwann cells. After crush injury, iNPCs, compared with GMSCs, displayed superior therapeutic effects on axonal regeneration at both the injury site and the distal segment of the injured sciatic nerve. Mechanistically, transplantation of GMSCs, especially iNPCs, significantly attenuated injury-triggered increase in the expression of c-Jun, a transcription factor that functions as a major negative regulator of myelination and plays a central role in dedifferentiation/reprogramming of Schwann cells into a progenitor-like state. Meanwhile, our results also demonstrate that transplantation of GMSCs and iNPCs consistently increased the expression of Krox-20/EGR2, a transcription factor that governs the expression of myelin proteins and facilitates myelination. Altogether, our findings suggest that transplantation of GMSCs and iNPCs promotes peripheral nerve repair/regeneration, possibly by promoting remyelination of Schwann cells mediated via the regulation of the antagonistic myelination regulators, c-Jun and Krox-20/EGR2.
Predoping effects of boron and phosphorous on arsenic diffusion along grain boundaries in polycrystalline silicon investigated by atom probe tomography
Authors: Takamizawa Hisashi , Shimizu Yasuo , Inoue Koji , Nozawa Yasuko , Toyama Takeshi , Yano Fumiko , Inoue Masao , Nishida Akio , Nagai Yasuyoshi 
Published: September 2016

Abstract
The effect of P or B predoping on As diffusion in polycrystalline Si was investigated by atom probe tomography. In all samples, a high concentration of As was found at grain boundaries, indicating that such boundaries are the main diffusion path. However, As grain-boundary diffusion was suppressed in the B-doped sample and enhanced in the P-doped sample. In a sample codoped with both P and B, As diffusion was somewhat enhanced, indicating competition between the effects of the two dopants. The results suggest that As grain-boundary diffusion can be controlled by varying the local concentration of P or B.
Is there any effect of pneumoperitoneum pressure on coagulation and fibrinolysis during laparoscopic cholecystectomy?
Authors: Donmez Turgut , Uzman Sinan , Yildirim Dogan , Hut Adnan , Avaroglu Huseyin Imam , Erdem Duygu Ayfer , Cekic Erdinc , Erozgen Fazilet 
Published: September 2016

BackgroundLaparoscopic cholecystectomies (LC) are generally performed in a 12 mmHg-pressured pneumoperitoneum in a slight sitting position. Considerable thromboembolism risk arises in this operation due to pneumoperitoneum, operation position and risk factors of patients. We aim to investigate the effect of pneumoperitoneum pressure on coagulation and fibrinolysis under general anesthesia.Material and MethodsFifty American Society of Anesthesiologist (ASA) I–III patients who underwent elective LC without thromboprophlaxis were enrolled in this prospective study. The patients were randomly divided into two groups according to the pneumoperitoneum pressure during LC: the 10 mmHg group (n= 25) and the 14 mmHg group. Prothrombin time (PT), thrombin time (TT), International Normalized Ratio (INR), activated partial thromboplastin time (aPTT) and blood levels of d-dimer and fibrinogen were measured preoperatively (pre), one hour (post1) and 24 h (post24) after the surgery. Moreover, alanine amino transferase, aspartate amino transferase and lactate dehydrogenase were measured before and after the surgery. These parameters were compared between and within the groups.ResultsPT, TT, aPTT, INR, and D-dimer and fibrinogen levels significantly increased after the surgery in both of the groups. D-dimer level was significantly higher in 14-mmHg group at post24.ConclusionBoth the 10-mmHg and 14-mmHg pressure of pneumoperitoneum may lead to affect coagulation tests and fibrinogen and D-dimer levels without any occurrence of deep vein thrombosis, but 14-mmHg pressure of pneumoperitoneum has a greater effect on D-dimer. However, lower pneumoperitoneum pressure may be useful for the prevention of deep vein thrombosis.