bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stakeholder perceptions of physical literacy: results from a national consultation in England
Authors: Duncan Michael J. , Essiet Inimfon , Hurter Liezel , Roberts William M. , Lewis Kiara , Goss Hannah , Morris Jade L. , Bingham Daniel D. , O’Brien Wesley , Barnett Lisa M. , Shearer Cara , Daly-Smith Andrew , Foweather Lawrence 
Published: October 2024

BackgroundThere is a lack of evidence of stakeholder perspective and understanding of physical literacy among relevant stakeholders from England. As part of research commissioned by Sport England to develop a physical literacy consensus statement for England, this study presents findings from the first national consultation with stakeholders in England.MethodsOne hundred and ninety-three individual stakeholders (50.3%) from education, community sport, national governing bodies of sport, physical activity and sport coaching sectors completed an online survey consisting of fixed item and open ended questions designed to examine their knowledge, understanding, perceptions and practices relating to physical literacy.ResultsResponses from stakeholders suggested there was confusion in use of the term physical literacy in practice and confusion regarding the definition of physical literacy. Most respondents suggested they were involved in physical literacy related activity and understood the term. However, when probed the physical literacy related activity they referred to was likely not actually physical literacy related. Understanding of the term physical literacy was inconsistent in general. Stakeholders considered the affective, social, physical and cognitive areas (domains) of learning to be most important for developing a positive relationship with movement, sport and physical activity for life.ConclusionsWhile stakeholders are aware of the term “physical literacy” and hold value of it within their practice, there remain key misconceptions relating to what physical literacy is, and debate as to whether any existing definitions truly capture the construct of physical literacy.
Impact of Harvest Method on Development of European Sea Bass Skin Microbiome during Chilled Storage
Authors: Angelakopoulos Rafael , Tsipourlianos Andreas , Fytsili Alexia E. , Giannoulis Themistoklis , Moutou Katerina A. 
Published: October 2024

European sea bass (Dicentrarchus labrax) is one of the most significant species farmed in the Mediterranean, yet a very perishable product. Its quality deteriorates rapidly as a result of three mechanisms: microbial activity, chemical oxidation, and enzymatic degradation. Microbial spoilage is the mechanism that contributes most to the quality deterioration of fresh and non-processed fish. To this end, our study aims to identify for the first time the combined effect of aquatic environment and harvest method on the composition and trajectory at storage at 0 °C of the European sea bass skin microbiome. Sampling was performed in two commercial fish farms in Western (WG) and Central Greece (CG) where fish were harvested using different methods: direct immersion in ice water or a mixture of slurry ice; application of electro-stunning prior to immersion in ice water. Samples were collected on harvest day and one week post-harvest. To profile the bacterial communities in the fish skin, 16S ribosomal RNA gene sequencing was used. The results and the following analyses indicated that the aquatic environment shaped the original composition of the skin microbiome, with 815 ASVs identified in the WG farm as opposed to 362 ASVs in the CG farm. Moreover, Pseudomonas and Pseudoalteromonas dominated the skin microbiome in the WG farm, unlike the CG farm where Shewanella and Psychrobacter were the dominant genera. All these genera contain species such as Shewanella putrefaciens, Pseudomonas aeruginosa, Pseudoalteromonas spp., and Psychrobacter sp., all of which have been implicated in the deterioration and spoilage of the final product. The different harvest methods drove variations in the microbiome already shaped by the aquatic environment, with electro-stunning favoring more diversity in the skin microbiome. The aquatic environment in combination with the harvest method appeared to determine the skin microbiome trajectory at storage at 0 °C. Although Shewanella had dominated the skin microbiome in all samples one week post-harvest, the diversity and the relative abundance of genera were strongly influenced by the aquatic environment and the harvest method. This study sheds light on the hierarchy of the factors shaping the fish skin microbiome and their importance for controlling post-harvest quality of fresh fish.
Transcriptome Remodeling in Arabidopsis: A Response to Heterologous Poplar MSL-lncRNAs Overexpression
Authors: Mao Jinyan , Tang Qianhua , Wu Huaitong , Chen Yingnan 
Published: October 2024

Stamens are vital reproductive organs in angiosperms, essential for plant growth, reproduction, and development. The genetic regulation and molecular mechanisms underlying stamen development are, however, complex and varied among different plant species. MSL-lncRNAs, a gene specific to the Y chromosome of Populus deltoides, is predominantly expressed in male flower buds. Heterologous expression of MSL-lncRNAs in Arabidopsis thaliana resulted in an increase in both stamen and anther count, without affecting pistil development or seed set. To reveal the molecular regulatory network influenced by MSL-lncRNAs on stamen development, we conducted transcriptome sequencing of flowers from both wild-type and MSL-lncRNAs-overexpressing Arabidopsis. A total of 678 differentially expressed genes were identified between wild-type and transgenic Arabidopsis. Among these, 20 were classified as transcription factors, suggesting a role for these regulatory proteins in stamen development. GO enrichment analysis revealed that the differentially expressed genes were significantly associated with processes such as pollen formation, polysaccharide catabolic processes, and secondary metabolism. KEGG pathway analysis indicated that MSL-lncRNAs might promote stamen development by upregulating genes involved in the phenylpropanoid biosynthesis pathway. The top three upregulated genes, all featuring the DUF295 domain, were found to harbor an F-box motif at their N-termini, which is implicated in stamen development. Additionally, in transgenic Arabidopsis flowers, genes implicated in tapetum formation and anther development were also observed to be upregulated, implying a potential role for MSL-lncRNAs in modulating pollen development through the positive regulation of these genes. The findings from this study establish a theoretical framework for elucidating the genetic control exerted by MSL-lncRNAs over stamen and pollen development.
Field Trial with Vaccine Candidates Against Bovine Tuberculosis Among Likely Infected Cattle in a Natural Transmission Setting
Authors: Ferrara Muñiz Ximena , García Elizabeth , Blanco Federico Carlos , Garbaccio Sergio , Garro Carlos , Zumárraga Martín , Dellagostin Odir , Trangoni Marcos , Marfil María Jimena , Bianco Maria Verónica , Abdala Alejandro , Revelli Javier , Bergamasco Maria , Soutullo Adriana , Marini Rocío , Rocha Rosana Valeria , Sánchez Amorina , Bigi Fabiana , Canal Ana María , Eirin María Emilia , Cataldi Angel Adrián 
Published: October 2024

Background/Objectives: Vaccines may improve the control and eradication of bovine tuberculosis. However, the evaluation of experimental candidates requires the assessment of the protection, excretion, transmission and biosafety. A natural transmission trial among likely infected animals was conducted. Methods: Seventy-four male heifers were randomly distributed (five groups) and vaccinated subcutaneously with attenuated strains (M. bovis Δmce2 or M. bovis Δmce2-phoP), a recombinant M. bovis BCG Pasteur (BCGr) or M. bovis BCG Pasteur. Then, they cohoused with a naturally infected bTB cohort under field conditions exposed to the infection. Results: A 23% of transmission of wild-type strains was confirmed (non-vaccinated group). Strikingly, first vaccination did not induce immune response (caudal fold test and IFN-gamma release assay). However, after 74 days of exposure to bTB, animals were re-vaccinated. Although their sensitization increased throughout the trial, the vaccines did not confer significant protection, when compared to the non-vaccinated group, as demonstrated by pathology progression of lesions and confirmatory tools. Besides, the likelihood of acquiring the infection was similar in all groups compared to the non-vaccinated group (p > 0.076). Respiratory and digestive excretion of viable vaccine candidates was undetectable. To note, the group vaccinated with M. bovis Δmce2-phoP exhibited the highest proportion of animals without macroscopic lesions, compared to the one vaccinated with BCG, although this was not statistically supported. Conclusions: This highlights that further evaluation of these vaccines would not guarantee better protection. The limitations detected during the trial are discussed regarding the transmission rate of M. bovis wild-type, the imperfect test for studying sensitization, the need for a DIVA diagnosis and management conditions of the trials performed under routine husbandry conditions. Re-vaccination of likely infected bovines did not highlight a conclusive result, even suggesting a detrimental effect on those vaccinated with M. bovis BCG.
The prescribing of opioids for chronic noncancer pain in the menopausal and postmenopausal population: a drug utilisation study in the United Kingdom
Authors: Tillyer Emma , Jani Yogini , Wei Li , Brauer Ruth 
Published: October 2024

BackgroundOpioid use for chronic noncancer pain (CNCP) is consistently higher in menopausal/postmenopausal women than in younger women or men, elevating their risk of opioid-related adverse health outcomes. Since pain severity increases with hormonal changes accompanying menopause, these women should be a focus of opioid stewardship efforts.AimTo examine opioid prescribing trends for CNCP in menopausal/postmenopausal women diagnosed with a musculoskeletal condition.Design & settingPopulation-based drug utilisation study using IQVIA Medical Research Data UK.MethodAnnual opioid prescribing incidence, prevalence, and average duration of use were calculated for a cohort of women aged 50-79 with musculoskeletal conditions newly diagnosed between 2010-2021. Specific results were stratified by age, pain indication, and Townsend score.ResultsFrom 2010 to 2021, incident prescribing rates of opioids increased in women aged 50-54 (161.4 [95% CI 149.7-174.0] per 1000 PYAR in 2010 to 239.6 [95% CI 211.7-271.2] per 1000 PYAR in 2021); these women discontinued opioid use faster (~1 year) than older age groups (~2 years). Overall, opioid prescribing prevalence decreased from 23% in 2010 to 14% in 2021, and average opioid use duration decreased from 3 years to 1 year (2010 - post-2017) in women aged 50-79.ConclusionThe overall observed decrease in prevalence and average duration of opioid use is encouraging. Incident prescriptions are rising in women aged 50-54 and those with fibromyalgia while remaining steady in women aged 55-79. Understanding the impact of menopause/post-menopause on opioid use trends is important for effective opioid stewardship.
Utilizing a Digital Escape Room to Improve Students’ Grasp and Understanding of Qualitative Research Methods
Authors: Dr Slyman Souad 
Published: October 2024

Utilizing the potential in game mechanisms for learning purposes is not new. This version of gaming for learning is about developing a Digital Escape Room (DER) revolving around a specific subject: qualitative research methods. Qualitative research methods have proved to be a difficult topic for many UG and PG students. It is thus important to develop tasks that will enable these students to obtain a deep learning experience. The significance of this project lies in that both qualitative and quantitative research methods seem to be difficult to learn for students. It seems to be a curriculum that the students need to invest more time learning than they expect and are willing to spend. Hence, seeking to utilize the potential that lies in immersive gaming. One of the aims of this project is to investigate if and how the DER approach will suit the step-by-step approach that is often used in qualitative research methods courses. Will this approach of solving puzzle-by-puzzle, and then combining answers in order to unlock the next level enable an emergence of more understandings of what the qualitative research is about? In this theoretical paper (work-in-progress), we will look at the DER literature and describe how the different components of the DER will contribute to pedagogical support regarding learning outcomes. In this next phase of this project, we are planning to develop our DER based on the current literature and previous evaluations of DERs, we will also conduct more semi-structure interviews, and further investigation is underway.
Low-temperature thermopower and phonon-drag effect in the quasi-one-dimensional cobaltate Ba3Co2O6(CO3)0.7
Authors: Komatsu Asuka , Sato Yoshiki J. , Yoshida Shogo , Okazaki Ryuji , Kurihara Ryosuke , Yaguchi Hiroshi 
Published: October 2024

Abstract
The quasi-one-dimensional cobaltate Ba3Co2O6(CO3)0.7 exhibits a high thermoelectric performance characterized by the large thermopower and high electrical conductivity above room temperature, while the low-temperature transport properties have been less investigated so far. Here, we systematically measure the thermopower of single-crystalline Ba3Co2O6(CO3)0.7 samples at low temperatures. The temperature dependence of the thermopower near room temperature is similar to that of other thermoelectric cobaltates, such as layered cobaltates, but exhibits a sample-dependent prominent peak structure near T = 40 K. We evaluate the sample dependence of the carrier density and the mobility and find that the saturation effect of phonon drag is essential for the observed peak structure in the thermopower. The enhanced thermopower utilizing a phonon-drag effect in the present material may be crucial for low-temperature thermoelectrics.
Evaluación del conocimiento para la mitigación del riesgo sísmico en la Unidad Educativa Básica Pedro Gual, Portoviejo- Manabí
Authors: Alvarado Medina Tnlg. Humberto Segundo , Galardy Domínguez Dra. Yelennis 
Published: October 2024

Ecuador, al ubicarse geográficamente sobre la confluencia de dos fallas tectónicas, como la placa de Nazca y la placa de Suramérica, tiene una actividad sísmica permanente que ha aumentado durante la última década. Las instituciones educativas, al albergar a un gran número de personas, se vuelven particularmente vulnerables durante eventos sísmicos, por lo que es necesario que se desarrollen estrategias efectivas para minimizar efectos negativos. En tal sentido, el objetivo de la investigación es evaluar el nivel de conocimiento y preparación del personal docente y administrativo, sobre las medidas de seguridad para la mitigación del riesgo sísmico en la Unidad Educativa Básica Pedro Gual, Portoviejo- Ecuador. Se realizó una investigación observacional, descriptiva, de corte transversal y retrospectiva; utilizando como métodos empíricos, un formulario de evaluación de vulnerabilidad sísmica estructural y dos encuestas, Pre-test y Pos-test, respectivamente, a una población de 20 personas, docentes y personal administrativo de la institución. Se obtuvo que la institución cuenta con un nivel de vulnerabilidad sísmica “Medio”, la mayoría de los participantes conocen su rol y responsabilidad ante un evento sísmico, los resultados de la evaluación del conocimiento del riesgo sísmico mejoraron significativamente posterior a la capacitación y el simulacro. Se concluye que es necesario implementar programas de capacitación y concienciación para mejorar el nivel de preparación y respuesta del personal docente, como responsables de ejecutar las medidas de seguridad del plan de emergencia.
Avances de la Vacuna para el Sars-Cov-2 en la actualidad
Authors: Sornoza Pincay Iris Kassandra , Castro Jalca Alexander Darío , Chinga Mera Julexi Jaqueline , Franco Mora Carlos Alberto 
Published: October 2024

La crisis sanitaria que generó el SARS-CoV-2 y el impacto que tuvo la economía a nivel mundial producen una presión alrededor de todo el mundo. A pesar de los grandes avances científicos que trajo el covid-19 con las vacunas, no existe aún un cura como tal para esta enfermedad. Por otro lado, con la aparición del covid-19, los científicos se vieron en la necesidad de crear pruebas para la detección del SARS-Cov-2, con el fin de identificar los casos positivos y poder tomar acción ante estos. El objetivo principal del artículo científico se enfocó en determinar cuáles han sido los avances de la vacuna y pruebas para el Sars-Cov-2, en la actualidad. Metodología: Para este estudio centró en el diseño documental narrativa, de tipo descriptivo. Resultados: Actualmente el uso de las vacunas forma parte de los métodos preventivos ante el Covid-19, la eficacia y eficiencia de las vacunas actualmente sobrepasan el 85% luego del estudio en fase III, por lo que son recomendadas para la población en general. Conclusiones: Hasta la actualidad existen varios métodos de detección de Covid-19, así como también vacunas utilizadas por los gobiernos de los diferentes países a nivel mundial, para brindar inmunización ante el covid-19 a personas que necesiten inmunización ante el riesgo de contraer Covid-19.
Abordaje creativo de los valores culturales desde el área de estudios sociales y su incidencia en la identidad cultural de los estudiantes de básica superior del circuito 13 D10 en el Cantón Pedernales
Authors: Loor Parrales Diana , Zambrano Montes, PhD Lubis Carmita 
Published: October 2024

La presente investigación tuvo como objetivo determinar el abordaje creativo de los valores culturales desde el área de estudios sociales y su incidencia en la identidad cultural de estudiantes. La investigación tuvo un enfoque cualicuantitativo, de tipo exploratoria y de campo, se aplicó la técnica de encuesta a estudiantes y docentes. El estudio se realizó en 12 centros educativos circuito 13D10 del cantón Pedernales Ecuador. La muestra fue no probabilística a criterio del investigador, por lo que se seleccionaron 30 estudiantes de octavo nivel de cada plantel educativo y 10 docentes que imparten clases en el área de Estudios Sociales. Los resultados evidencian insuficiencias en el conocimiento y abordaje creativo de valores culturales y prácticas pedagógicas que no responden a las necesidades formativas de los estudiantes. Se concluye que los docentes aplican procedimientos didácticos tradicionales con un proceso formativo poco participativo, sin propuestas innovadoras y creativas que motiven a los estudiantes a ser protagonistas en el proceso de enseñanza y aprendizaje. La realidad detectada no se compadece con las necesidades estudiantiles que pueden incidir en un bajo desempeño académico y en su actuación como un ciudadano que se prepara para un futuro donde ejerza su rol con conciencia social.
Retos en la gestión de proyectos tecnológicos
Authors: Morales Carrillo MgSc. Jessica , Bravo Cobeña Wismar , Cedeño Intriago Bryan , Manzana Lucas Johana 
Published: October 2024

La presente investigación tiene por objetivo, identificar los principales inconvenientes o errores en la ejecución de proyectos tecnológicos identificando los motivos principales por lo cual fueron proyectos fallidos. Para el desarrollo de la investigación se empleó la revisión sistemática de literatura, donde se inició determinando las palabras clave para la búsqueda, identificando los factores de exclusión e inclusión, se prosiguió con la estructuración y clasificación de la información mediante una matriz, que incluye como campos los proyectos fallidos y los 18 errores principales, mismos que fueron considerados del libro “18 Grandes Errores en la Administración de Proyectos y como evitarlos”, donde se realizó una clasificación de acuerdo con el análisis desarrollado por los autores de cada proyecto, identificando el o los errores más evidentes; para concluir el desarrollo, se realizó un análisis, de los errores más frecuentes y sus alternativas de solución. Como resultado de la investigación se pudo identificar que, de los proyectos tecnológicos actuales, tanto de pequeñas como grandes organizaciones, los principales errores que se evidencian según la investigación realizada fueron “no prestamos atención a los riesgos del proyecto, ni a las cuestiones de administración”, “utilizamos la tecnología equivocada”, “intentamos hacer demasiado” y “no realizamos suficientes pruebas”; lo que proporciona una comprensión más profunda de la naturaleza y la relevancia de los errores en la gestión de proyectos, identificando la importancia de la planificación, comunicación y responsabilidad en la prevención y mitigación de estos errores.
Innovación Metodológica para Emprendimientos en Guerrero
Authors: Santos Prudente Jhoana Karen , Rodríguez Rosales Antonio Alfonso , Zavala Bush Claudia Bertha 
Published: October 2024

Este trabajo se realizó para apoyar a personas emprendedoras que han desarrollado proyectos de innovación tecnológica en el Centro de Investigación Científica y Tecnológica de Guerrero A.C. (CICTEG), ya que surge la necesidad de que estas mentes creativas quieren ir más allá de compromisos académicos. La metodología trabajada se aplicó en la primera unidad de emprendimiento representada por la empresa De Guerrero Para el Mundo S.A.S. de C.V. (DGPM), que trabajó con pre-incubación e incubación de ideas de negocios derivadas de proyectos estudiantiles en el Estado de Guerrero. La idea es aportar en la difusión de la metodología para el desarrollo de nuevas colaboraciones y aperturar líneas de investigación aplicada en desarrollo regional con temas de contaminación y medio ambiente, química de alimentos, educación, desarrollos tecnológicos, energías alternas, e instrumentación, por mencionar algunos. También con el presente trabajo se busca empezar a hablar sobre el desarrollo de los emprendimientos con base tecnológica en Guerrero, la educación del emprendimiento, procesos mejorados que puedan brindar fomentar la apertura a través de las alianzas entre los diferentes sectores. Ya que el emprendimiento es una actividad que puede impulsar el desarrollo de la ciencia, tecnología, así como la economía en el sur del país.