bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive prehabilitation for older adults undergoing elective surgery: a systematic review and narrative synthesis
Authors: He Yu , Wang Ziliang , Zhao Yinuo , Han Xiaochai , Guo Kangxiang , Sun Nianyi , Liu Xueyong 
Published: October 2024

BackgroundPerioperative cognitive maintenance and protection in older adults is an important patient safety imperative. In addition to foundational care, one area of growing interest is integrating cognitive prehabilitation into the surgical trajectory. This review aimed to evaluate the effectiveness and safety of cognitive prehabilitation on cognitive functional capacity and postoperative cognitive outcomes among older adults undergoing elective surgery.MethodsThe MEDLINE, Embase, CENTRAL, CINAHL, PsycINFO, PEDro, CBM, CNKI, WANFANG, and VIP databases were systematically searched up to September 5, 2024, to identify randomized controlled trials published for English or Chinese. Two authors independently completed the study selection process, data extraction process and methodological quality assessment. The Patient, Intervention, Comparison, Outcome, Study design framework was used to construct the search strategy. The predefined primary outcomes of interest included the incidence of postoperative delirium (POD) and the incidence of delayed neurocognitive recovery (dNCR). The quality of the studies was evaluated by the PEDro scale. Owing to the small number of trials and clinical and methodological diversity, a narrative synthesis was undertaken in accordance with the Synthesis Without Meta-analysis guidelines. This study was conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation system.ResultsSix studies were analysed. These trials involved 645 total participants, with 316 in the intervention group (mean age, 66.0–73.8 years; 38.4–77.8% male) and 329 in the comparator group (mean age, 67.5–72.6 years; 31.8–88.9% male). The effects of preoperative cognitive training on reducing the incidence of dNCR, the incidence of POD, the length of hospital stay and the incidence of postsurgical complications as well as improving postoperative global cognitive function and activities of daily living are quite uncertain. The results of this study should be interpreted with caution owing to the limited number of trials and low to very low certainty of evidence.ConclusionCurrent evidence on the effectiveness and safety of cognitive prehabilitation on cognitive and noncognitive outcomes in older patients undergoing elective surgery is limited and unclear.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=277191, Identifier CRD42021277191.
The association between body roundness index and osteoporosis in American adults: analysis from NHANES dataset
Authors: Zhang Xunmeng , Liang Jiarong , Luo Hong , Zhang Huanhuan , Xiang Jing , Guo Lianjin , Zhu Xuemin 
Published: October 2024

BackgroundAn innovative way to quantify obesity that appropriately captures levels of visceral and body fat is the Body Roundness Index (BRI). The purpose of this study is to look at the relationship between BRI and osteoporosis (OP) in adult Americans.MethodsThis study utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 2007 and 2018. NHANES is a research program designed to assess the health and nutritional status of adults and children in the United States. It conducts surveys focusing on various populations and health-related topics. Logistic regression analysis was employed to investigate the relationship between BRI and OP, adjusting for various covariates. BRI was categorized into four levels to further explore the association trends between different BRI levels and OP, enhancing the robustness of the results. Using restricted cubic spline (RCS) analysis, the dose–response relationship between BRI and OP was illustrated. Subgroup analyses were also carried out to evaluate the consistency and robustness of the findings.ResultsThis study included 8,899 participants aged 50 years and older, among whom 763 had OP. BRI and the prevalence of OP were inversely correlated in the fully adjusted model (OR = 0.79, 95% CI: 0.69–0.86). The prevalence of OP considerably reduced with higher BRI levels when BRI was converted from a continuous to a categorical variable in comparison to the lowest BRI quartile. RCS analysis revealed an L-shaped negative correlation between BRI and OP prevalence, with a threshold effect analysis identifying a breakpoint at BRI = 5.29. Each unit increase in BRI to the left of this breakpoint was linked to a 36% decrease in the probability of OP (OR = 0.64, 95% CI: 0.57–0.72). Based on stratified factor subgroup analyses, it was shown that the negative correlation between BRI and OP persisted.ConclusionIn a large, representative sample of American adults, this study identified a significant negative correlation between BRI and the prevalence of OP. Specifically, as BRI increases, the prevalence of osteoporosis decreases. Maintaining an appropriate and healthy BRI level may play a critical role in the prevention of osteoporosis. Therefore, regular monitoring of BRI and the adoption of appropriate health measures are essential for reducing the risk of osteoporosis.
The prevalence and determinants of social anxiety disorder among people living with HIV/AIDS in Southwestern Ethiopia: a cross-sectional study
Authors: Alemayehu Yadeta , Adem Hussen Mustefa , Abdu Zakir , Dule Aman , Hajure Mohammedamin , Mulatu Gebremeskel , Gezimu Wubishet , Alemu Solomon Seyife , Wedajo Lema Fikadu 
Published: October 2024

BackgroundSocial anxiety disorder imposes impacts of functional disability, poor educational achievement, loss of work productivity, social impairment, greater financial dependency, and impairment in quality of life. Therefore, the aim of this study was to assess the prevalence and identify determinants of social anxiety disorder among people living with HIV/AIDS.MethodsA cross-sectional study was conducted from 1 to 30 May 2022 among 354 people living with HIV using a simple random sampling technique. The Social Phobia Inventory (SPIN) Scale was used to assess the presence of social anxiety disorder. Data were gathered using chart review tools and a structured questionnaire, which was administered by a pretested face-to-face interviewer. SPSS version 25 was used to analyse the data once they were imported into EpiData Manager version 4.6. Binary and multivariable logistic regressions were performed. After calculating odds ratios with a 95% confidence interval (CI), statistical significance was established at p &lt; 0.05.ResultsA total of 336 respondents participated in the study, resulting in a response rate of 94.91%. The magnitude of social anxiety disorder was 32.44% (95% CI: 27.4, 37.2). Being female [adjusted odds ratio (AOR) = 3.55, 95% CI: 1.61, 7.84], having a stage III/IV HIV/AIDS status (AOR = 3.17, 95% CI: 1.10, 9.13), being alcohol dependent (AOR = 2.81, 95% CI: 1.45, 5.44), and having perceived stigma (AOR = 5.62, 95% CI: 2.95, 10.72) were predictors of social anxiety disorder.ConclusionIn this study, approximately one-third of people living with HIV/AIDS had social anxiety disorder. Being female, having a stage III/IV HIV/AIDS status, being alcohol dependent, and having perceived stigma were predictors of social anxiety disorder. Therefore, training for health care providers on the screening, counselling, and management of social anxiety disorder is important.
Association of clozapine with structural and resting-state functional abnormalities of the hippocampus in chronic schizophrenia
Authors: Joo Sung Woo , Kim Sang Kyoung , Lee Won Hee , Kim Se Hyun , Lee Jungsun 
Published: October 2024

IntroductionAbnormalities in the hippocampus have been extensively reported in schizophrenia research. However, inconsistent findings exist, and how structural and functional abnormalities of the hippocampus are associated with clinical symptoms in schizophrenia, especially concerning clozapine treatment, remains uncertain.MethodsWe recruited 52 patients with schizophrenia, each with an illness duration of at least 5 years, and categorized them based on clozapine treatment. T1-weighted images and resting-state functional magnetic resonance imaging scans were obtained and analyzed to perform group comparisons of the structural and functional changes in the hippocampus. Volumes of the hippocampal subregions, as well as resting-state functional connectivity maps from these areas were compared between the groups. Associations with clinical symptoms, including the severity of psychiatric symptoms and cognitive functions, were investigated.ResultsThe clozapine group (n=23) exhibited smaller volumes in several hippocampal subregions, including the CA1, CA4, granule cell and molecular layers of the dentate gyrus, compared to the non-clozapine group (n=29). Seven clusters with significant group differences in functional connectivity with these hippocampal subregions were identified, with six of these clusters showing increased functional connectivity in the clozapine group. The reduced volumes of the hippocampal subregions were moderately associated with the severity of negative symptoms, general intelligence, and executive function.DiscussionPatients with schizophrenia undergoing clozapine treatment exhibited smaller volumes in the hippocampal subregions, which were moderately associated with negative symptoms and cognitive functions, compared to those without clozapine treatment.
Comparing the prevalence and influencing factors of postpartum depression in primiparous and multiparous women in China
Authors: Zhang Jing , Wang Peipei , Fan Weisen , Lin Cuixia 
Published: October 2024

BackgroundFew studies have compared the influencing factors of postpartum depression between primiparous and multiparous women. Therefore, this study is aimed to investigate the prevalence and influencing factors of postpartum depression in primiparous and multiparous women, and provide reference suggestions for clinical nursing.MethodsA total of 429 postpartum women who gave birth at a Maternal and Child Health Hospital in Shandong Province, China, from April to June 2024, were recruited by convenience sampling. A Sociodemographic Questionnaire, Edinburgh Postpartum Depression Scale, Pittsburgh Sleep Quality Index, and Perceived Social Support Scale were used for investigation. SPSS 26.0 was used to analyze the data, and multivariate regression was employed to analyze the influencing factors of postpartum depression between primiparous and multiparous women.ResultsThe total prevalence of postpartum depression among 429 postpartum women (191 primiparas and 238 multiparas) was 22.14%. The prevalence of postpartum depression among primiparous and multiparous women were 21.99% and 22.27%, respectively, with no statistically significant difference [OR=1.016, 95% CI (0.642, 1.608)]. Sleep quality is a common protective factor for postpartum depression in both primiparous and multiparous women, while perceived social support is another protective factor for multiparous women. The risk factors are different in both two group, there is no risk factor found in primiparous women, the newborns health and women’s expectation on newborns gender are risk factors for postpartum depression in multiparous women.ConclusionsBoth primiparous and multiparous women have a high risk of postpartum depression. In order to promote the mental health of postpartum women, precise nursing measures should be adopted for different parity of postpartum women in clinical practice.
Understanding the well-being of residents in Chinese Continuing Care Retirement Communities—a case of Shanghai
Authors: Wang Xuechun , Xia Bo , Skitmore Martin , Volz Kristy , Shu Bodi 
Published: October 2024

IntroductionChina is one of the world’s fastest-aging countries. Continuing Care Retirement Communities (CCRCs) have emerged as a viable option for accommodating and serving older adults. However, Chinese CCRCs are still in the early stages, and comprehensive research on resident well-being is still deficient. The study aims to assess how well residents in CCRCs are faring in terms of their psychological and physical health, considering China’s aging population and changing societal structures.MethodsAfter a thorough literature review to pinpoint relevant well-being measures in psychological and physical health, the study implemented a survey to capture residents’ experiences and perceptions, and subsequently analyzed how well-being correlates with demographic characteristics.Results and discussionThe results show that while Chinese CCRCs can enhance residents’ well-being through personalized care and social activities, challenges such as psychological distress and declining physical health remain. Demographic factors, including living situation and length of stay, also affect residents’ well-being. The study emphasizes the importance of ongoing research and evaluation to guide evidence-based practices and improve CCRCs continuously. Overall, it offers a comprehensive analysis of the wellbeing of Chinese CCRCs residents, shedding light on both psychological and physical health aspects and providing valuable insights for enhancing CCRCs design, implementation, and evaluation in China and elsewhere.
Apodanthera glaziovii (Cucurbitaceae) Shows Strong Anti-Inflammatory Activity in Murine Models of Acute Inflammation
Authors: Andrade Maria Lorena de Oliveira , Marinho Pedro Artur Ferreira , Oliveira Alisson Macário de , Souza Thalisson Amorim de , Cibulski Samuel Paulo , Alves Harley da Silva 
Published: October 2024

Background/objectives: Apodanthera glaziovii is an endemic species from the semi-arid Brazilian, which has limited toxicological and pharmacological studies. This species belongs to a well-studied family known for its bioactive compounds used in treating inflammatory. This study aimed to identify secondary metabolites in the stems from A. glaziovii, evaluate toxicity, and investigate the anti-inflammatory potential of the stem hydroalcoholic extract (SHE-Ag). Methods: qualitative and quantitative assays were employed to identify secondary metabolites, along with chromatographic analyses and 1H and 13C NMR. Toxicity was assessed through in vitro hemolytic toxicity, in vivo genotoxicity, and oral acute toxicity tests before the pharmacological assays were conducted. Results: phytochemical screening, HPLC and NMR analyses suggested the presence of saponins of the norcucurbitacin class. The SHE-Ag exhibited no hemolytic activity and no mutagenic potential. However, in vivo toxicity at a dose of 2000 mg/kg revealed hematological and biochemical alterations, while the 500 mg/kg dose was safe. In the anti-inflammatory assays, SHE-Ag at 100 mg/kg reduced paw edema by 55.8%, and leukocyte and neutrophil migration by 62% and 68% in the peritonitis model, respectively; inflammatory cell migration by 70% in the air pouch model, outperforming indomethacin, which showed a 54% reduction. Conclusions: these findings indicate that SHE-Ag is rich in saponins, confirmed through HPLC and 1H and 13C NMR analyses. The SHE-Ag also demonstrated low toxicity. The inflammation models used showed a reduction in inflammation, pro-inflammatory cells, and edema, highlighting the significant anti-inflammatory activity of hydroethanolic extract A. glaziovii stems.
تحليل لتوقعات مقدمي خدمات البريد بالكويت تجاه ممارسة إدارة الجودة الشاملة: دراسة ميدانية
Authors: الحسين رائد عباس , الصايغ وديع عبدالله 
Published: October 2024

تُعد هذه دراسة أولية تهدف إلى التحقيق في اتجاه شركات خدمات التوصيل في الكويت تجاه تطبيق مفهوم إدارة الجودة الشاملة (TQM) وتأثيره على أداء الأعمال ورضا العملاء. تم تصميم استبيان وتنفيذه باستخدام نموذج إدارة الجودة الشاملة في إعداد البريد (MPTQM). وقد تم تخصيص الاستبيان ليتناسب مع معايير شركات خدمات التوصيل، وتم توزيعه على 23 شركة توصيل في الكويت، والتي تمثل حجم العينة قيد الدراسة. حُللت النتائج باستخدام اختباري مان-ويتني وكروسكال-واليس غير المعلميين. وتبين أن اتجاه شركات خدمات التوصيل في الكويت نحو ممارسات إدارة الجودة الشاملة لا يؤثر على أداء الأعمال أو رضا العملاء. أدت هذه النتيجة غير المتوقعة إلى مزيد من التحقيق مع الشركات التي شاركت في الدراسة. قد تسلط النتائج الضوء على مجال بحث جديد يمكن أن يساعد في تقديم رؤى إضافية بشأن تنفيذ إدارة الجودة الشاملة في أنواع مختلفة من الصناعات في الكويت.
SOSIALISASI PEMBERDAYAAN ECOPRINT SEBAGAI SARANA PENINGKATAN PEREKONOMIAN MASYARAKAT
Authors: Abdullah Siti Sarah , Fitriani Ida , Musrifah Ai , Nazilah Siti , Setiawati Fietri , Rispianti Rispianti 
Published: October 2024

Ecoprint yaitu proses mentransfer warna dan bentuk bahan alami ke dalam bahan serat alami secara langsung tanpa menggunakan bahan sintesis atau kimia. Oleh karena itu batik ecoprint ini lebih ramah lingkungan dan tidak menimbulkan pencemaran lingkungan. Produk yang dihasilkan ecoprint berupa tas, baju, dan sejenisnya yang memiliki nilai jual. Saparantu Ecocraft sebagai UMKM, pelopor dalam pembuatan usaha ecoprint di Cianjur telah melakukan pelatihan pembuatan ecoprint di beberapa Desa di Cianjur. Namun penerimaan masyarakat untuk memproduksi kerajinan tersebut hanya 10%. Alasan kurang minatnya dikarenakan pembuatan produksi ecoprint sulit. Padahal keuntungan yang akan mereka dapatkan jika konsisten menggeluti bidang ini dapat berkali lipat, karena minim modal yaitu dengan cara memanfaatkan bahan di sekitar lingkungan. Solusi permasalahan tersebut yaitu dengan menginternalisasi masyarakat mengenai manfaat yang didapatkan untuk tekun di bidang ecoprint sehingga mereka mendapatkan manfaatnya. Kesulitan pembuatan disolusikan dengan dibuatnya tutorial pembuatan ecoprint. Objek dalam pengabdian masyarakat ini yaitu kader PKK sebagai penggerak di Desa Sirnagalih. Telah dilakukan pelatihan dan sosialisasi tutorial pembuatan ecoprint. Dengan adanya tutorial, dapat membantu pengrajin dalam mempraktekkan. Agar masyarakat luas dapat mempraktekkan cara pemuatan ecoprint maka pihak Saparantu Ecocraft mengunggah hasil video tutorial melalui media sosial youtube.
Armenian Colony on the Don According to the Materials of «Topographical and Statistical Description of the Trading Town of Nakhchivan in 1807» by Baron Balthasar von Campenhausen
Authors: Батиев Л.В. 
Published: October 2024

В статье, на основании ранее не введенного в научный оборот архивного источника – первого полного описания Нахичеванской армянской колонии, составленного таганрогским градоначальником бароном Б.Б. Кампенгаузеном, – всесторонне рассматриваются организация и жизнедеятельность города Нахичевана (на Дону) и окружающих его сел, основанных в соответствии с грамотой Екатерины II армянами, переселенными из Крыма в 1778-1779 гг. Автор статьи, вслед за составителем «Описания», анализирует состав населения колонии, его социальную (сословную) и профессиональную структуру, обеспеченность землей горожан и поселян и значение земельных владений для бюджета города. Сведения о количестве и состоянии жилых домов, лавок, магазинов, кофеен, трактиров, постоялых дворов, а также церквей и других городских общественных сооружений, характеристика городского хозяйства, водоснабжения города и его благоустройства дают достаточно полную картину жизни города. «Описание» Б.Б. Кампенгаузена доказывает, что в Нахичеване были развиты не только торговля (местная и транзитная), но и ремесло и промышленное производство (рыбные, кожевенные, кирпичные, черепичные и др. заводы). Помимо этого, рассмотрены также финансовое состояние города и организация его управления.
The article, based on the archival source – the first full description of the Nakhchivan Armenian colony, compiled by the Governor of Taganrog, Baron Balthasar von Campenhausen – comprehensively examines the organization and activities of the town of Nakhchivan (on the Don) and its surrounding villages, founded in accordance with the charter of Catherine II by Armenians resettled from the Crimea in 1778-1779. The author of the article, following the compiler of the «Description», analyzes the composition of the colony's population, its social and professional structure, the land supply of townspeople and settlers and the importance of land holdings for the city's budget. Information about the number and condition of the dwelling houses, stores, coffee houses, taverns, inns, as well as churches and other urban public buildings is given. Provided are the characteristics of the urban economy, water supply and its improvement. Therefor given a fairly complete picture of the life of the city. Baron's Balthasar von Campenhausen «Description» proves that not only trade (local and transit), but also crafts and industrial production (fish, tannery, brick, tile and other factories) were developed in Nakhchivan. In addition, the financial state of the city and the organization of its management are also considered.
Prevención del desarrollo de Sibilancias y de Asma Bronquial en niños de alto riesgo con Ketotifeno
Authors: Freyre Roman Eleodoro , Rebaza Gonzales Rodolfo 
Published: October 2024

Con el propósito de evaluar la eficacia profiláctica del Ketotifeno en la prevención del desarrollo ulterior de episodios de sibilancias en niños no asmáticos, pero de alto riesgo según una escala elaborada con anterioridad, se estudiaron dos grupos de 21 años cada uno, similares entre sí respecto a la edad, distribución por sexo y puntaje de riesgo al inicio del estudio. A los niños de uno de los grupos se les administró Ketotifeno y a los del otro no, siguiéndoseles durante 12 meses para estimar el desarrollo de sibilancias en ese período.
Se investigó, también, la frequencia de factores ambientales del hogar como la presencia de fumadores, de animales domésticos, de cuartos alfombrados y el número de hermanos menores de 10 años. Estos factores fueron similares en ambos grupos.
Al encontrarse una alta correlación entre el puntaje de riesgo y el número de episodios de sibilancias en el grupo no tratado con Ketotifeno, se confirmó el valor de la escala empleada.
El grupo tratado con Ketotifeno presentó un número significativamente menor de niños que hicieron sibilancias y de episodios de sibilancias para el grupo, siendo las diferencias más marcadas a partir del tercer mes de seguimiento.
Se concluye que el Ketotifeno es eficaz reduciendo el desarrollo de sibilancias en niños no asmáticos de alto riesgo y se recomienda su uso.
Enfermedad de Legg-Calve-Perthes: Tratamiento con Yesos
Authors: Benavente Arce Fernando 
Published: October 2024

Se revisan los conceptos actuales sobre la Enfermedad de Legg-Calvé-Perthes; que las inmovilizaciones muy prolongados de la cadera afectada producen problemas psicológicos en los pacientes y sus familiares, y que los resultados funcionales logrados con ellos, no son superiores a los logrados con otros métodos.
En el presente trabajo comparamos los resultados personales de tres métodos de contención de la cabeza femoral dentro del acetábulo, empleando yesos de abducción en pacientes con CATTERALL III-IV. Se empleó yeso Inhauser en 27 pacientes (32 caderas); Petrie en 10 pacientes (11 caderas), Broom Stick en 8 pacientes (9 caderas).
A pesar del corto período de seguimiento hemos logrado mejores resultados con yeso de Broom Stick y Petrie, mejorando previamente la movilidad con tracción cutánea y terapia física. Los resultados se evalúan basados en el sistema de Stulberg.