bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecological Management of Stored Grain Pests: Global Insights and Future Directions
Authors: El Baghazaoui Rachid , Houssine Bouiamrine El , Nassiri Laila , Boutagayout Abdellatif , Belmalha Saadia 
Published: October 2024

AbstractPost-harvest losses due to pests in cereals and pulse warehouses represent a major challenge to global food security. These losses have widespread negative impacts on the food supply chain, leading to the widespread use of synthetic insecticides to control the spread of pests in stored commodities. Although these chemicals are initially effective against warehouse pests, their prolonged use leads to increased resistance, resulting in increased health and environmental risks. In addition, the residues left by these synthetic insecticides can alter the quality of stored food, thereby posing a threat to human and animal health. In response to this problem, several studies have focused on ecological management aimed at combating warehouse pests without compromising the quality of stored grain. These studies include an assessment of traditional, ecological, and modern approaches as well as a summary of technological advances in cereal storage. This analysis describes new emerging ecological methods such as varietal resistance, use of semiochemicals, and physical and biological control methods. The challenges and research prospects associated with ecological practices were also discussed. It is emphasized that ecological control is not only safer and more sustainable in the long term but also contributes to the preservation of the environment and human health by reducing exposure to harmful substances.
Fabrication of hierarchically porous trabecular bone replicas via 3D printing with high internal phase emulsions (HIPEs)
Authors: Sengokmen-Ozsoz Nihan , Aleemardani Mina , Palanca Marco , Hann Alice , Reilly Gwendolen C , Dall’Ara Enrico , Claeyssens Frederik 
Published: October 2024

Abstract
Combining emulsion templating with additive manufacturing enables the production of inherently porous scaffolds with multiscale porosity. This approach incorporates interconnected porous materials, providing a structure that supports cell ingrowth. However, 3D printing hierarchical porous structures that combine semi-micropores and micropores remains a challenging task. Previous studies have demonstrated that using a carefully adjusted combination of light absorbers and photoinitiators in the resin can produce open surface porosity, sponge-like internal structures, and a printing resolution of about 150 µm. In this study, we explored how varying concentrations of tartrazine (0, 0.02, 0.04, and 0.08 wt%) as a light absorber affect the porous structure of acrylate-based polymerized medium internal phase emulsions fabricated via vat photopolymerization. Given the importance of a porous and interconnected structure for tissue engineering and regenerative medicine, we tested cell behavior on these 3D-printed disk samples using MG-63 cells, examining metabolic activity, adhesion, and morphology. The 0.08 wt% tartrazine-containing 3D-printed sample (008 T) demonstrated the best cell proliferation and adhesion. To show that this high internal phase emulsion (HIPE) resin can be used to create complex structures for biomedical applications, we 3D-printed trabecular bone structures based on microCT imaging. These structures were further evaluated for cell behavior and migration, followed by microCT analysis after 60 days of cell culture. This research demonstrates that HIPEs can be used as a resin to print trabecular bone mimics using additive manufacturing, which could be further developed for lab-on-a-chip models of healthy and diseased bone.
Standalone single- and bi-layered human skin 3D models supported by recombinant silk feature native spatial organization
Authors: Gkouma Savvini , Bhalla Nayanika , Frapard Solène , Jönsson Alexander , Gürbüz Hakan , Dogan Asli Aybike , Giacomello Stefania , Duvfa Martin , Ståhl Patrik L , Widhe Mona , Hedhammar My 
Published: October 2024

Abstract
Physiologically relevant human skin models that include key skin cell types can be used for in vitro drug testing, skin pathology studies, or clinical applications such as skin grafts. However, there is still no golden standard for such a model. We investigated the potential of a recombinant functionalized spider silk protein, FN-silk, for the construction of a dermal, an epidermal, and a bilayered skin equivalent (BSE). Specifically, two formats of FN-silk (i.e. 3D network and nanomembrane) were evaluated. The 3D network was used as an elastic ECM-like support for the dermis, and the thin, permeable nanomembrane was used as a basement membrane to support the epidermal epithelium. Immunofluorescence microscopy and spatially resolved transcriptomics analysis demonstrated the secretion of key ECM components and the formation of microvascular-like structures. Furthermore, the epidermal layer exhibited clear stratification and the formation of a cornified layer, resulting in a tight physiologic epithelial barrier. Our findings indicate that the presented FN-silk-based skin models can be proposed as physiologically relevant standalone epidermal or dermal models, as well as a combined BSE.
The impact of green credit on the green transformation of the manufacturing industry
Authors: Gao Dawei , Ma Meichen 
Published: October 2024

Abstract
Manufacturing’s green transformation is essential for advancing high-quality development. Green credit, which functions as a market-driven tool, offers support for achieving this transformation. Using manufacturing data from 30 provinces in China from 2005 to 2020, this research establishes a theoretical framework to analyze how green credit and marketization levels influence manufacturing’s green transformation. This research also provides an empirical analysis of how green credit influences this transition. The results are as follows: first, the growth of green credit plays a significant role in driving the green transformation of the manufacturing sector, with this finding remaining valid after a series of robustness and endogeneity tests. Second, the mechanism analysis shows that green credit supports the environmentally friendly transformation of the manufacturing industry through an improvement in R&D intensity. Third, moderation testing reveals that the process of marketization significantly strengthens the positive effect of green credit on the promotion of manufacturing’s green transformation Among them are the following, the relationship between the government and the market and the development of the product market inhibit the role of green credit in support of the green transformation of the manufacturing sector. The development of factor markets, the development of non-state-owned economies, and the development of market intermediary organizations and the legal system environment exert a facilitating function, which significantly enhances the positive effect of green credit in the promotion of the green transformation. The conclusions provide fresh insights and empirical evidence for advancing manufacturing’s green transformation and hold practical significance for refining green credit policies and advancing market-oriented reforms.
Optimization of microstructure and mechanical properties of 7075 aluminum alloy by equal channel angular pressing technology
Authors: Xu Gang , Li Shilin 
Published: October 2024

Abstract
The equal channel angular pressing technology, as an effective technique for modifying the surface of a material, has had a significant impact on the microstructure and mechanical properties of the 7075 aluminum alloy. The study achieved the refinement of 7075 aluminum alloy grains and the homogenization of the second phase particle distribution through equal channel angular pressing technology, thereby significantly improving the strength and plasticity of the material. Through orthogonal experimental design, the effects of extrusion angle, extrusion speed, and remelting temperature on material properties were studied. The results showed that appropriate ECAP parameters could effectively regulate the microstructure of 7075 aluminum alloy, thereby optimizing its mechanical properties. Especially in the analysis of equivalent strain rate, when the extrusion angle was 50°, the position of the maximum equivalent strain rate at the forefront point remained unchanged, but the equivalent strain rate decreased to 0.107−1. In the aging hardness analysis, when the number of equal channel angular pressing passes was 3, the aging hardness of G group 7075 aluminum alloy increased to 195HV in the first 5 min. The equal channel angular pressing technology can optimize the internal structure of 7075 aluminum alloy and improve the material’s plasticity and mechanical properties. The research provides important technical support for the application of 7075 aluminum alloy in high-end equipment manufacturing.
A rolling bearing fault signal denoising algorithm that combines a new adaptive information entropy with a new wavelet threshold function
Authors: Li Min , Li Xuemei , Liu Bin , Lv Shangsong , Liu Chengjie 
Published: October 2024

Abstract
Mechanical fault diagnosis is of great significance to industrial automation, and extracting vibration fault signals is one of the important tasks in mechanical health monitoring and fault diagnosis. However, due to the complex working environment of rolling bearings, a large amount of noise makes it difficult to extract vibration fault signals. Denoising the vibration signal of bearings can remove interference noise, simplify the early identification of signal features, and thus improve diagnostic accuracy and mechanical maintenance efficiency. This paper proposes a rolling bearing fault signal denoising algorithm, which constructs a new feature extraction and denoising function. This method first decomposes the noisy signal into Intrinsic Mode Functions (IMFs) by Intrinsic Computing Expressive Empirical Mode Decomposition with Adaptive Noise (ICEEMDAN). Secondly, a new adaptive information entropy threshold function is constructed to extract the noisy IMFs from it. Then, the noisy IMF signal is denoised by a new wavelet threshold function. Finally, the noise-free IMFs are reconstructed to reconstruct the denoised signal. To verify the actual performance of the algorithm, comparative experiments were conducted on a self-collected dataset and a public dataset, the results show that this method improves the continuity of signal reconstruction and can remove various types of vibration fault noise signals more effectively and accurately, thereby improving the fault detection accuracy by 2%–9%.
A generalized framework for identification and geometrical feature extraction of circular and polygonal shaped prisms
Authors: Vala Rushiraj , Chauhan Mihir , Sanghvi Harshal A , Hashemi Javad , Pandya Abhijit 
Published: October 2024

Abstract
This paper introduces a versatile framework crucial for robotic applications such as object manipulation, mobile robot navigation, and pole climbing. It addresses the identification of geometric shapes and dimensions of diverse objects found in varied environments. The proposed method utilizes LiDAR scanning to capture objects from different angles, generating point clouds merged through transformations and superimpositions. After filtering and slicing, intersections are isolated and projected onto a chosen datum plane. The framework employs Non-Linear Least Square fitting via Gauss Newton iterative approach, utilizing pseudo-inverse Jacobian of a hypotrochoid to approximate polygons. The algorithm consecutively fits polygon prisms, determining the best fit with the least norm of error. Results indicate an average least square error of less than 9% for radius fitting and a high f-score for shape identification.
Automated design of digital filters using convolutional neural networks for extracting ringdown gravitational waves
Authors: Sakai Kazuki , Odonchimed Sodtavilan , Takano Mitsuki , Takahashi Hirotaka 
Published: October 2024

Abstract
The observation of gravitational waves is expected to allow new tests of general relativity to be performed. As the gravitational wave signal is hidden by detector noise in observed data, a method to reduce noise is required to analyze the ringdown phase of gravitational wave signals. Recently, some noise reduction methods based on a neural network have been proposed; however, the results of these methods must be considered with caution because the output can contain spurious components. To overcome this limitation, in this study, we developed a neural network–based method to design optimal digital filters for extracting ringdown gravitational wave signals. In this method, no spurious components appear in the output because the digital filters reduce the noise. We conducted simulations with waveforms of gravitational waves from binary black hole coalescence and confirmed that the proposed method designs appropriate filters that reduce detector noise.
Green Foreign Energy Policy
Authors: Prontera Andrea 
Published: October 2024

AbstractThis chapter presents the analytical framework adopted in this book to analyse, compare, and explain the green foreign energy policies of the major international actors. It highlights the building blocks of green foreign energy policy and its differences from fossil fuel foreign energy policy before illustrating the main drivers of green foreign energy policy, the issue areas in which it can be analytically organized and empirically mapped, and the tools of statecraft that governments can deploy to achieve their objectives in this field. A four-dimensional matrix comprising an issue areas dimension, a tools dimension, a mode of engagement dimension, and a geographical dimension is developed for the study of green foreign energy policies. The chapter also discusses the internal–external nexus and the role of state–market relations in this field. Finally, it illustrates the green power strategies that major international actors can pursue in the context of the global energy transition.
The European Union
Authors: Prontera Andrea 
Published: October 2024

AbstractThis chapter analyses the green foreign energy policy and green power strategy of the EU. First, it explains how climate and technological sovereignty priorities have emerged in Europe, prompting a greening of the EU regulatory state and a shift towards a catalytic state. These processes intensified under the Juncker Commission and subsequent von der Leyen Commission; the latter, with the European Green Deal, has placed the energy transition at the centre of EU internal and external action. Moreover, the chapter illustrates the further innovations introduced after the Covid-19 crisis and the Russian invasion of Ukraine amid a deterioration of the international landscape and growing competition with China. These developments have produced an overall greening of the EU external action, although its green power strategy must still face important constraints that limit its ability to act as a leader in the emerging low-carbon world.
The United States
Authors: Prontera Andrea 
Published: October 2024

AbstractThis chapter analyses the US green foreign energy policy and green power strategy. First, it illustrates the evolution of the US renewable energy and green industrial policies, highlighting the challenges that they encounter amid the growing politicization of climate issues. The chapter then illustrates the development of the US green internal and external approaches under Obama and Trump. Trump sought to dismantle many of the innovations introduced by Obama; however, the US renewable energy complex resisted those changes. Moreover, because of the growing rivalry with China, important innovations continued to materialize, even during the Trump administration. Finally, the chapter illustrates the recent major shift under Biden—the US has increased its domestic and international efforts to regain a leadership position in the global energy transition. This is being accomplished through an economic green power strategy that is coordinated with the US global military posture and involves US allies and partners.
Pharmacotherapy of acute ST-elevation myocardial infarction and the pharmacist’s role, part 1: Patient presentation through revascularization
Authors: Hyland Sara J , Eaton Rachael E , Max Marion E , Egbert Susan B , Wong Stephanie A , Blais Danielle M 
Published: October 2024

Abstract

Purpose
Key pharmacotherapeutic modalities and considerations for the patient with ST-elevation myocardial infarction (STEMI) across the critical initial phases of care are reviewed.

Summary
Despite established value in the emergency department (ED), cardiac care, and intensive care settings, there is currently little published literature describing or supporting clinical pharmacist roles in the acute management of STEMI. The high-risk period from hospital presentation through revascularization and stabilization involves complex pharmacotherapeutic decision points, many operational medication needs, and multiple layers of quality oversight. While rife with opportunities for pharmacists to optimize care, this timeframe appears inconsistently targeted by clinical pharmacy services, which may halt after ED evaluation and then resume upon postcatheterization cardiac unit admission. Herein we review the key pharmacotherapeutic modalities and considerations for the patient with STEMI across the critical initial phases of care. These include supportive therapies prior to revascularization, the host of antithrombotics involved in revascularization by percutaneous coronary intervention and/or fibrinolysis, and other periprocedural medications. Important practice guidelines and clinical resources are summarized from the clinical pharmacist perspective, and roles and responsibilities of the responding pharmacist are suggested. A companion article will extend the review to periprocedural adverse event management, key early decision-making regarding long-term risk reduction, and pharmacist involvement in institutional quality improvement efforts. We aim to support inpatient pharmacy departments in advancing clinical services for this critical patient population, and we call for further research delineating pharmacist impact on patient and institutional STEMI outcomes.

Conclusion
Patients presenting with STEMI rapidly traverse multiple phases of care and receive a host of antithrombotic and supportive medications during acute management, presenting many important pharmacotherapeutic decision points and roles for pharmacists.
Large-volume intravenous fluid use before and after implementation of a fluid conservation strategy
Authors: Carr John , Orvin Dustin 
Published: October 2024

Abstract

Purpose
We describe the implementation of a fluid conservation strategy in a 2-hospital community health system and its effects on utilization of 1,000-mL bags of 0.9% sodium chloride and lactated Ringer’s solution.

Summary
Disruptions to medical supply chains are unpredictable and can cause significant impacts on patient care. A fluid conservation strategy including guidance statements and mandatory order modifications in a 2-hospital community health system was associated with decreases in the use of 1,000-mL bags of 0.9% sodium chloride and lactated Ringer’s solutions of 52% and 39%, respectively, compared with the utilization rates over the prior year.

Conclusion
Institutions facing shortages should consider multidisciplinary strategies with trackable metrics when faced with supply chain disruptions.
Polylactic acid-based dressing with oxygen generation and enzyme-like activity for accelerating both light-driven biofilm elimination and wound healing
Authors: Wen Tianci , Xiong Shilang , Zhao Huihui , Wang Junzhe , Wang Chunming , Long Zhisheng , Xiong Long , Qian Guowen 
Published: October 2024

Abstract

Background
Photodynamic therapy (PDT) is a widely used therapeutic approach for eradicating bacterial biofilms in infected wound, but its effectiveness is limited by the hypoxic environment within the biofilm. This study aimed to investigate whether the efficiency of photodynamic removing biofilm is improving by providing oxygen (O2), as well as the expression of cytokines involved in infected wound healing.

Methods
Manganese dioxide (MnO2) nanoparticles with catalase-like activity were grown in situ on graphitic phase carbon nitride (g-C3N4, CN) nanosheets to construct an all-in-one CN-MnO2 nanozyme, which was then incorporated into poly-L-lactic acid (PLLA) to prepare CN-MnO2/PLLA wound dressing by electrospinning. Subsequently, the in vitro antibacterial biofilm ratio and antibacterial ratio of CN-MnO2/PLLA wound dressing were examined by spread plate and crystal violet staining under irradiation with 808 nm near-infrared light and 660 nm visible light. Meanwhile, the rat skin injury model was established, and hematoxylin and eosin (H&E), Masson’s, tumor necrosis factor-α (TNF-α), Arginase 1 (Arg-1), vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (BFGF) were evaluated in vivo to assess the effect of CN-MnO2/PLLA wound dressing on wound healing.

Results
Biofilm density caused by Staphylococcus aureus and Pseudomonas aeruginosa had elimination rates of 83 and 62%, respectively, when treated with CN-MnO2/PLLA dressing. Additionally, the dressing exhibited high antibacterial efficacy against both bacteria, achieving 99 and 98.7% elimination of Staphylococcus aureus and Pseudomonas aeruginosa, respectively. Furthermore, in vivo experiments showed that the CN-MnO2/PLLA wound dressing achieved complete healing of infected wounds on Day 14, with a wound healing rate of &gt;99% by increasing collagen deposition, expression of anti-inflammatory cytokine Arg-1, vascularization cytokine VEGF, and epithelial cell BFGF, and inhibiting the expression of inflammatory cytokine TNF-α.

Conclusions
The CN-MnO2/PLLA wound dressing exhibited excellent antibacterial properties in vitro and in vivo. In addition, CN-MnO2/PLLA wound dressing accelerated rapid wound healing through an anti-inflammatory, pro-vascular regeneration and skin tissue remodeling mechanism.
Cutaneous melanoma in situ: a review
Authors: Karponis Dimitrios , Joshy Jilse , Stratigos Ioannis A , Craig Paul J , Mistry Khaylen , van Bodegraven Birgitta , Venables Zoe C , Levell Nick J 
Published: October 2024

Abstract
Cutaneous melanoma in situ (MIS), also known as ‘stage 0 melanoma’, is a collection of malignant melanocytes in the epidermis and epithelial adnexa, without evidence of microinvasion to the papillary dermis. Distinct histological subtypes include lentigo maligna (LM), superficial spreading (SS) MIS and acral lentiginous (AL) MIS. LM is the most common subtype, usually diagnosed later in life (median age at diagnosis of 66–72 years) and associated with cumulative ultraviolet radiation exposure. SS MIS is associated with intense episodes of sun exposure and is more common on the trunk and extremities. AL MIS is seen in nonhair-bearing skin. AL MIS, although rare (0.6% of MIS in England), is found in a higher proportion in more pigmented skin types compared with other MIS subtypes. Most international studies between 1990 and 2019 report rising incidence for MIS. US data show a decline in the incidence of LM between 2015 and 2019. For 2013–2019 in England, the recorded incidence of LM is plateauing, whereas that of other MIS is rising. Definitive diagnosis of MIS is by histological examination of biopsied skin with immunohistochemistry but can be supported with dermoscopy and reflectance confocal microscopy. Surgical treatment (excision or Mohs micrographic surgery) is the gold standard. Depending on MIS subtype, other options such as cryotherapy, topical imiquimod, radiotherapy or watchful waiting may be appropriate. The latest 5-year net-survival rates in England between 2013 and 2015 are 98.6% for AL MIS and exceed 100% for all other MIS. This review summarizes the aetiology, pathogenesis, epidemiology, diagnosis and management of MIS.