bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishment of Personalized Pain Goals in Oncology Patients to Improve Care and Decrease Costs
Authors: Zylla Dylan , Larson Amber , Chuy Gladys , Illig Lisa , Peck Adina , Van Peursem Sarah , Fulbright James W. , Pawloski Pamala A. , Richter Sara , Mettner Jeanne 
Published: February 2017

Purpose: Cancer-related pain is common, negatively affects quality of life and survival, and often requires treatment with opioid analgesics. Patient-reported data that describe the incidence and severity of pain, medication use, and patient satisfaction with care are lacking. Methods: We analyzed 18 months of outpatient oncology clinic encounters from the electronic medical record to obtain data on pain levels and opioid and nonopioid treatments. In June 2014, we instituted a pain intervention by creating a pain management information handout for patients, educating clinicians on opioid cost-effectiveness, and implementing a nursing protocol to document personalized pain goals (PPGs). Results: Moderate to severe pain was reported in nearly 15% of patient encounters. We observed an increase in the percentage of encounters with a documented PPG of 16% to 71% ( P < .001). On average, PPG was achieved in 84% of patients. Rates of high-cost long-acting opioid prescriptions (oxycodone controlled release and fentanyl patches), as a total of all long-acting opioids, declined from 45% preintervention to 33% postintervention ( P = .005). Conclusion: Our intervention improved rates of PPG documentation and decreased the number of prescriptions for high-cost long-acting opioids. Oncology clinics can implement simple quality improvement methods, such as asking patients about their PPG and educating clinicians about opioid costs, to improve outcomes and lower treatment costs.
Adaptive holographic interferometer based on optically addressed spatial light modulator for high-sensitivity optical fiber sensing
Authors: Peigné Arnaud , Bortolozzo Umberto , Residori Stefania , Molin Stéphanie , Nouchi Pascale , Dolfi Daniel , Huignard Jean-Pierre 
Published: February 2017

Abstract
Adaptive holographic interferometry is a promising method for high-sensitivity phase-modulation measurements in the presence of slow perturbations from the environment. This technique is based on the use of a nonlinear recombining medium. We report the realization of an adaptive holographic interferometer relying on an optically addressed liquid crystal spatial light modulator operating at 1.55 μm. The beam-coupling process that occurs in a GaAs-liquid crystal device, allows obtaining a phase-modulation sensitivity of 200 μrad/sqrt (Hz) at 1 kHz. The interferometer behaves as an optical high-pass filter, with a cutoff frequency of approximately 10 Hz, thus, filtering slow-phase disturbances, such as due to temperature variations or low-frequency fluctuations, and keeping the detection linear without the need of heterodyne or active stabilization. Moreover, owing to the basic principle of holography, this technique can be used with complex wave fronts such as the speckled field reflected by a highly scattering surface or the optical field at the output of a multimode optical fiber. We demonstrate both theoretically and experimentally that using a multimode optical fiber as a sensing element, rather than a single-mode fiber, allows improving the interferometer phase sensitivity. Finally, we present a phase-optical time domain reflectometry (OTDR) optical fiber sensor using the adaptive holographic interferometer.
Sleep-related breathing biomarkers as a predictor of vital functions
Authors: Proniewska Klaudia , Pregowska Agnieszka , Malinowski Krzysztof Piotr 
Published: February 2017

Abstract
Because an average human spends one third of his life asleep, it is apparent that the quality of sleep has an important impact on the overall quality of life. To properly understand the influence of sleep, it is important to know how to detect its disorders such as snoring, wheezing, or sleep apnea. The aim of this study is to investigate the predictive capability of a dual-modality analysis scheme for methods of sleep-related breathing disorders (SRBDs) using biosignals captured during sleep. Two logistic regressions constructed using backward stepwise regression to minimize the Akaike information criterion were extensively considered. To evaluate classification correctness, receiver operating characteristic (ROC) curves were used. The proposed classification methodology was validated with constructed Random Forests methodology. Breathing sounds and electrocardiograms of 15 study subjects with different degrees of SRBD were captured and analyzed. Our results show that the proposed classification model based on selected parameters for both logistic regressions determine the different types of acoustic events during sleep. The ROC curve indicates that selected parameters can distinguish normal versus abnormal events during sleep with high sensitivity and specificity. The percentage of prediction for defined SRBDs is very high. The initial assumption was that the quality of result is growing with the number of parameters included in the model. The best recognition reached is more than 89% of good predictions. Thus, sleep monitoring of breath leads to the diagnosis of vital function disorders. The proposed methodology helps find a way of snoring rehabilitation, makes decisions concerning future treatment, and has an influence on the sleep quality.
Body composition and somatotype of judo athletes and untrained male students as a reference group for comparison in sport
Authors: Buśko Krzysztof , Pastuszak Anna , Kalka Ewa 
Published: February 2017

Summary
Study aim: The aim of this study was to determine the body composition and somatotype of untrained male students studying at Warsaw University of Technology in 2011, in order to create a current reference group for comparison, and to investigate the difference in body build of male judoists compared with the non-athlete group.
Materials and methods: Fifteen male judo athletes (age 18.6 ± 1.9 years, body height 177.4 ± 8.5 cm, body mass 80.3 ± 15.8 kg, training experience 10.0 ± 2.8) and 154 male untrained students of the Warsaw University of Technology (age 20.1 ± 0.9 years, body height 180.9 ± 7.2 cm, body mass 75.6 ± 10.9 kg) participated in the study. Somatotype was determined using the Heath- Carter method.
Results: The mean somatotype of the untrained students was 3.94.62.9, whilst that of the judo athletes was 3.25.91.8; the groups differed significantly in their mesomorphy and ectomorphy components. Significant differences between the groups were found in breadth of wrist, bicristal diameter and arm circumference (p < 0.05). The groups were also significantly different in body composition as estimated by BIA and anthropometric methods (p < 0.05).
Conclusion: The morphological characteristics of the judo athletes differed from those of the untrained men. The somatic profile of body build for athletes in this sport seems to be optimal for achieving high results, the somatotype not having changed since the 1990s.
Late physiotherapy rehabilitation changes gait patterns in post-stroke patients
Authors: Almeida Aline do Socorro Soares Cardoso , Viana da Cruz Alex Tadeu , Candeira Skarleth Raissa Andrade , Cardoso do Nascimento Nathalya Ingrid , Santana de Castro Ketlin Jaquelline , Costa de Lima Ramon , Generoso Campos Pinho Barroso Tatiana , Souza Givago da Silva , Callegari Bianca 
Published: February 2017

Summary
Study aim: To determine whether a physiotherapy protocol improves the electromyographic activation (EA) during the hemiparetic gait in patients with delayed access to rehabilitation.
Material and methods: 40 post-stroke patients underwent clinical evaluation and gait assessment at the time of admission and at the end of treatment.
Results: The anterior leg muscles tibialis anterior and rectus femoris had earlier onset (p = 0.0001).
Conclusion: Electromyographic findings showed altered patterns during the hemiparetic gait cycle, even in patients with delayed access to treatment.
Alzheimer’s disease as an inflammatory disease
Authors: Bolós Marta , Perea Juan Ramón , Avila Jesús 
Published: February 2017

Abstract
Alzheimer’s disease (AD) is a neurodegenerative condition characterized by the formation of amyloid-β plaques, aggregated and hyperphosphorylated tau protein, activated microglia and neuronal cell death, ultimately leading to progressive dementia. In this short review, we focus on neuroinflammation in AD. Specifically, we describe the participation of microglia, as well as other factors that may contribute to inflammation, in neurodegeneration.
A Study on Bandwidth and Performance Limitations of Array Vibration Harvester Configurations
Authors: Aboulfotoh Noha , Twiefel Jens 
Published: February 2017

Abstract
Many researchers introduced an array of generators for broadband energy harvesting. The array has been studied in comparison to a single element from this array, but never compared to a single reference harvester with same volume as the whole array. This paper presents a theoretical study of evaluating the performance of the array harvester in comparison to the reference harvester. Power from the reference harvester as well as from the array is analytically calculated. The array is compared to the reference harvester when loaded by their optimal resistances which provide maximum power capability. The comparison is divided into two sections: firstly when the elements of the array are tuned to resonate at matching frequencies and secondly when they are tuned to non-matching resonance frequencies. The comparisons lead to two significant limits of the working bandwidth of the array: the lower and the upper limit. Between the two limits, the power produced from the array is less than the reference harvester, but with a small additional bandwidth. Below the lower limit, the array has no advantage over the reference harvester. Above the upper limit, output power of the array is inconsistent. Hence, design guidelines for the array are provided.
Three-dimensional ultrasound for prenatal assessment of conjoined twins: additional advantages?
Authors: Wataganara Tuangsit , Ruangvutilert Pornpimol , Sunsaneevithayakul Prasert , Russameecharoen Kusol , Nawapun Katika , Phithakwatchara Nisarat 
Published: February 2017

AbstractConjoined twins are a rare, but serious, complication of monozygotic twins. Early prenatal diagnosis of conjoined twins is increasingly made with transvaginal ultrasound and color Doppler studies. Most prenatally diagnosed conjoined twins are terminated due to the high perinatal mortality, but advancement in pediatric surgery has allowed for successful postnatal separation in a small number of cases, and some parents may consider this option over termination of pregnancy. It is important to get a detailed prenatal ultrasound for the site and extent of fusion for an accurate categorization. Three-dimensional ultrasound (3DUS) provides images that can facilitate counselling for the parents. Additional information that impacts on diagnosis, prognostication, and perinatal management of conjoined twins could be obtained from selective use of 3DUS, particularly those with atypical fetal union. Most of the proposed additional benefits of 3DUS are based on case reports. Magnetic resonance imaging (MRI) has been increasingly used for the purpose of identifying intricate organ sharing. Because of the rarity of this condition, and the heterogeneity of fetal fusion, added benefits of either 3DUS or MRI for prenatal diagnosis and perinatal management of conjoined twins have not been demonstrated by well-conducted clinical trials. This article aims to review clinical application of various 3DUS display modes in prenatal assessment of conjoined twins, focusing on their potential additional benefits, risks and misuses. 3DUS may help detecting additional findings that are not possible with 2DUS, but, it has not been scientifically shown to improve the survival rate of the twins or reduce maternal morbidity.
Phonotactic c(l)ues to Bantu noun class disambiguation
Authors: Braver Aaron , Bennett Wm. G. 
Published: February 2017

AbstractWhile a number of phonologists assume that phonotactics can provide clues to abstract morphological information, this possibility has largely gone unconsidered in work on Bantu noun classes. We present experimental evidence from isiXhosa (a Bantu language of the Nguni family, from South Africa), showing that speakers make use of root phonotactics when assigning noun classes to nonce words. Nouns in Xhosa bear class-indicating prefixes, but some of these prefixes are homophonous – and therefore ambiguous. Our findings show that when speakers are presented with words that have prefixes ambiguous between two classes, phonotactic factors can condition them to treat the nouns as one class or the other. This suggests that noun class (and other abstract morphological information) is not only stored in the lexicon, but is also redundantly indicated by phonotactic clues.
Haematological Indices in Trypanosoma Brucei Brucei (Federe Isolate) Infected Nigerian Donkeys (Equus Asinus) Treated with Homidium and Isometamidium Chloride
Authors: Oparah Queen Nneka , Sackey Anthony Bedu kojo , Lawal Idris Alao , Abdullahi Usman Shehu 
Published: February 2017

AbstractThe efficacy of intramuscular administration of Homidium chloride (Novidium®) and Isometamidium chloride (Sécuridium®) in Nigerian donkeys (Equus asinus) experimentally infected with T. b. brucei (Federe isolate) was investigated. Changes in haematological and serum biochemical indices were evaluated using clinical haematology and biochemistry methods. Red blood cell (RBC) count for the negative control group was significantly higher than for the positive control, Novidium® and Sécuridium®-treatment groups. Haemoglobin (Hb) concentration significantly reduced in the infected untreated group compared with other groups. Packed cell volume (PCV) was significantly different between negative and positive controls, and also between the infected untreated and treatment groups. There was significant reduction in platelet counts post-infection and post-treatment. Mean corpuscular volume (MCV) increased significantly in the treatment groups while mean corpuscular haemoglobin concentration (MCHC) significantly reduced only in the Sécuridium®-treatment group. Lymphocyte count for infected untreated was non-significantly higher than for the uninfected controls, but treatment with both trypanocides recorded further increases, which were higher compared with that of the uninfected group. Post infection and treatment, aspartate aminotransferase (AST) levels increased significantly. There were non-significant differences in electrolyte ion concentrations across the groups except for chloride ion which recorded a significant reduction in the Novidium®-treatment group. This experiment revealed that Nigerian donkeys infected with T. brucei brucei (Federe isolate) developed symptoms of trypanosomosis; anaemia, lymphocytosis and thrombocytopenia. Treatment with the trypanocides ameliorated effects of the infection, and results suggest that immunosuppression may not be a substantial clinical manifestation of T. brucei brucei (Federe isolate) trypanosomosis in Nigerian donkeys.
Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response
Authors: Savarin Monika , Kamensek Urska , Cemazar Maja , Heller Richard , Sersa Gregor 
Published: February 2017

Abstract

Background
Tumor irradiation combined with adjuvant treatments, either vascular targeted or immunomodulatory, is under intense investigation. Gene electrotransfer of therapeutic genes is one of these approaches. The aim of this study was to determine, whether gene electrotransfer of plasmid encoding shRNA for silencing endoglin, with vascular targeted effectiveness, can radiosensitize melanoma B16F10 tumors.

Materials and methods
The murine melanoma B16F10 tumors, growing on the back of C57Bl/6 mice, were treated by triple gene electrotransfer and irradiation. The antitumor effect was evaluated by determination of tumor growth delay and proportion of tumor free mice. Furthermore, histological analysis of tumors (necrosis, apoptosis, proliferation, vascularization, presence of hypoxia and infiltration of immune cells,) was used to evaluate the therapeutic mechanisms.

Results
Gene electrotransfer of plasmid silencing endoglin predominantly indicated vascular targeted effects of the therapy, since significant tumor growth delay and 44% of tumor free mice were obtained. In addition, irradiation had minor effects on radioresistant melanoma, with 11% of mice tumor free. The combined treatment resulted in excellent effectiveness with 88% of mice tumor free, with more than half resistant to secondary tumor challenge, which was observed also with the plasmid devoid of the therapeutic gene. Histological analysis of tumors in the combined treatment group, demonstrated similar mode of action of the gene electrotransfer of plasmid encoding shRNA for silencing endoglin and devoid of it, both through the induction of an immune response.

Conclusions
The results of this study indicate that irradiation can in radioresistant melanoma tumors, by release of tumor associated antigens, serve as activator of the immune response, besides directly affecting tumor cells and vasculature. The primed antitumor immune response can be further boosted by gene electrotransfer of plasmid, regardless of presence of the therapeutic gene, which was confirmed by the high radiosensitization, resulting in prolonged tumor growth delay and 89% of tumor free mice that were up to 63% resistant to secondary challenge of tumor. In addition, gene electrotransfer of therapeutic plasmid for silencing endoglin has also a direct effect on tumor vasculature and tumors cells; however in combination with radiotherapy this effect was masked by pronounced immune response.
Research Concerning The Distribution of Temperature in Asphalt Mixtures with The Help of Thermo-Physical Characteristics for Laboratory Tests
Authors: Marc Paul , Costescu Ciprian 
Published: February 2017

Abstract
The characterization of the material through laboratory tests performed on asphalt mixtures offers significant performance predictions for asphalt pavements only when the material temperature is correctly taken into consideration. This paper presents an analytical pattern which, based on the thermo-physical characteristics, can predict correctly the distribution of temperatures in the mass of asphalt mixtures.
The paper also presents the organizational structure of laboratory testing, designed to validate the model for temperature determination. The temperature measurements are realized on a range of cylindrical samples at different moments in time, after submitting the sample from a low balance condition to a high balance condition by placing it in the environment precinct, according to the future test.
In conclusion, the paper aims at realizing and developing a model as a practical instrument able to offer a reliable assessment concerning the time required in order to reach the testing temperature specified for the samples of asphalt mixtures for different laboratory trials.
“Warm Mix Asphalt’’ for Airport Use
Authors: Petcu Claudia , Răcănel Carmen 
Published: February 2017

Abstract
“Warm Mix Asphalt” (WMA) is a technology developed to obtain an asphalt mixture at lower temperatures. The method has significant benefits for the economic and environmental area.
As known, “warm mix asphalt” uses additives in bitumen having the purpose to reduce the viscosity in order to decrease the mixing and compaction temperatures.
Hot mix asphalt used in the airport area, especially the area of taxiway and the apron must satisfy beside usual requirements for roads, some requirements related to fuel resistance and de-icing agents according to European norms.
Does warm mix asphalt for airport use meet the requirements according to European norms? This is the question from this paper which aims to determine the characteristics of asphalt mixtures for airports BBA16 when using or not using an additive, considering a series of laboratory tests: cyclic triaxial compression test, fatigue test, stiffness modulus test and resistances to fuels test.
Producing Cheap Food and Labour: Migrations and Agriculture in the Capitalistic World-Ecology
Authors: Gerbeau Yoan Molinero , Avallone Gennaro 
Published: February 2017

Abstract
Through the perspective of world-ecology, one of the most recent approaches in international relations, we aim to analyse global capitalism as an ecological project based on the appropriation of human and extra-human nature oriented to support capital accumulation process. Agriculture and its labour force occupy a central role in maintaining the world-system in which global chains, international migrations and centre-periphery relationships interact. This paper shows how global processes occur at this intersection. The aim of this paper is to contribute to the analysis of the current world-system through this innovative approach, developed mainly by Jason W. Moore, and then show how the world-system’s structure and its crisis have articulated a highlyinternationalized production model whose most significant effect has been the generation of large migrations of cheap labour across the planet. It is also proposed to descend to the local context to highlight examples because the organization of work at this territorial scale is representative of global agricultural production.
Repetition as Trapped Emotion in Tennessee Williams’s the Glass Menagerie
Authors: Kusovac Olivera , Pralas Jelena 
Published: February 2017

AbstractRepetition as a linguistic and stylistic device extensively used in Tennessee Williams’s plays has been noticed by many. At the same time, more psychologically-inclined scholars have frequently drawn parallels between Williams’s plays and his own experiences and emotional conflicts. In an attempt to combine the two perspectives, this article will explore the function of repetitions as indicators of trapped emotions in Williams’s celebrated and award-winning play The Glass Menagerie. Starting from the stylistic theoretical background, but at the same time taking into account the psychological insights into the link between Williams’s life and work through some basic concepts of Freud and Lacan, an attempt will be made to demonstrate that in this play linguistic repetition appears as an obsessive expression of the characters’ emotions as well as those of the dramatist himself, making him repeat and relive both his experiences and his emotions. The authors will first introduce the concept and functions of repetition as a linguistic and stylistic device and then explore its representative instances in individual characters and their meanings, ending with the parallels which can be drawn between the characters’ and the dramatist’s own experiences and emotions expressed or intensified through repetitions.