bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ionic liquid solvents: the importance of microscopic interactions in predicting organic reaction outcomes
Authors: Keaveney Sinead T. , Haines Ronald S. , Harper Jason B. 
Published: January 2017

Abstract
Ionic liquids are attractive alternatives to molecular solvents as they have many favourable physical properties and can produce different organic reaction outcomes compared to molecular solvents. Thus far, interactions between the ionic liquid components and specific sites (such as charged centres, lone pairs and π systems) on the reagents and transition state have been identified as affecting reaction outcome; a comprehensive understanding of these interactions is necessary to allow prediction of ionic liquid solvent effects. This manuscript summarises our recent progress in the development of a framework for predicting the effect of an ionic liquid solvent on the outcome of organic processes. There will be a particular focus on the importance of the different interactions between the ionic liquid components and the species along the reaction coordinate that are responsible for the changes in reaction outcome observed in the cases described.
Displacement assay methodology for pseudorotaxane formation in the millisecond time-scale
Authors: García-Martínez Fernando , Quiroga Miguel , Rodríguez-Dafonte Pedro , Parajó Mercedes , Garcia-Rio Luis 
Published: January 2017

Abstract
Rotaxanes, formed by an axis through the cavity of a macrocycle, are promising systems for the construction of molecular machines. A very limited number of experimental techniques are available for mechanistic studies since only mechanical bonds are formed, being NMR one of the most widely used. The major inconvenience derived from NMR use is the time-scale for threading/dethreading processes lasting a few minutes in the case of faster processes. In the present manuscript, we report the application of a new kinetic methodology based on a displacement assay for cyclodextrin-based pseudorotaxane formation. By coupling a very fast (microseconds time-scale) binding/dissociation of nitrophenol to α-CD with a dicationic axle threading/dethreading process, we have been able to study kinetic processes taking place in the millisecond time-scale.
Analytical solution for the correlator with Gribov propagators
Authors: Šauli Vladimir 
Published: January 2017

Abstract
Propagators approximated by meromorphic functions with complex conjugated poles are widely used to model the infrared behavior of QCD Green’s functions. In this paper, analytical solutions for two point correlators made out of functions with complex conjugated poles or branch points have been obtained in the Minkowski space for the first time. As a special case the Gribov propagator has been considered as well. The result is different from the naive analytical continuation of the correlator primarily defined in the Euclidean space. It is free of ultraviolet divergences and instead of Lehmann it rather satisfies Gribov integral representation.
Electrochemical behavior of uranyl in anhydrous polar organic media
Authors: Burn Adam G. , Nash Kenneth L. 
Published: January 2017

Abstract
Weak complexes between pentavalent and hexavalent actinyl cations have been reported to exist in acidic, non-complexing high ionic strength aqueous media. Such “cation-cation complexes” were first identified in the context of actinide-actinide redox reactions in acidic aqueous media relevant to solvent extraction-based separation systems, hence their characterization is of potential interest for advanced nuclear fuel reprocessing. This chemistry could be relevant to efforts to develop advanced actinide separations based on the upper oxidation states of americium, which are of current interest. In the present study, the chemical behavior of pentavalent uranyl was examined in non-aqueous, aprotic polar organic solvents (propylene carbonate and acetonitrile) to determine whether UO2
+ cations generated at the reducing working electrode surface would interact with the UO2
2+ cations in the bulk phase to form cation-cation complexes in such media. In magnesium perchlorate media, the electrolyte adsorbed onto the working electrode surface and interfered with the uranyl reduction/diffusion process through an ECE (electron transfer/chemical reaction/electron transfer) mechanism. In parallel studies of uranyl redox behavior in tetrabutylammonium hexafluorophosphate solutions, an EC (electron transfer/chemical reaction) mechanism was observed in the cyclic voltammograms. Ultimately, no conclusive electrochemical evidence demonstrated uranyl cation-cation interactions in the non-aqueous, aprotic polar organic solvent solutions, though the results reported do not completely rule out the presence of UO2
+·UO2
2+ complexes.
Advanced Exergy Analysis of a Turbofan Engine (TFE): Splitting Exergy Destruction into Unavoidable/Avoidable and Endogenous/Exogenous
Authors: Balli Ozgur 
Published: January 2017

AbstractA conventional and advanced exergy analysis of a turbofan engine is presented in this paper. In this framework, the main exergy parameters of the engine components are introduced while the exergy destruction rates within the engine components are split into endogenous/exogenous and avoidable/unavoidable parts. Also, the mutual interdependencies among the components of the engine and realistic improvement potentials depending on operating conditions are acquired through the analysis. As a result of the study, the exergy efficiency values of the engine are determined to be 25.7 % for actual condition, 27.55 % for unavoidable condition and 30.54 % for theoretical contion, repectively. The system has low improvement potential because the unavoidable exergy destruction rate is 90 %. The relationships between the components are relatively weak since the endogenous exergy destruction is 73 %. Finally, it may be concluded that the low pressure compressor, the high pressure compressor, the fan, the low pressure compressor, the high pressure compressor and the combustion chamber of the engine should be focused on according to the results obtained.
Focus of Attention for Diagnostic Testing of the Force-Velocity Curve
Authors: Brady Claire , Comyns Thomas , Harrison Andrew , Warrington Giles 
Published: January 2017

ABSTRACT
DIAGNOSTIC TESTING OF VARIOUS POINTS ON THE FORCE-VELOCITY CURVE, SUCH AS MAXIMUM STRENGTH AND RUNNING SPEED TESTS, IS USED TO IDENTIFY ATHLETES' STRENGTHS AND WEAKNESSES. DURING THE IMPLEMENTATION OF THESE TESTS, COACHES TYPICALLY USE VERBAL INSTRUCTIONS IN AN ATTEMPT TO ENSURE THE ATHLETE ACHIEVES THE HIGHEST RESULT POSSIBLE. RESEARCHERS HAVE SHOWN THAT OPTIMAL MOTOR SKILL PERFORMANCE IS OFTEN ACHIEVED WHEN VERBAL INSTRUCTIONS DIRECT ATTENTION EXTERNALLY. THIS ARTICLE REVIEWS THE CURRENT RESEARCH ON THE APPROPRIATE ATTENTIONAL FOCUS FOR TESTS, WHICH ASSESS ASPECTS OF THE FORCE-VELOCITY CURVE. BASED ON AN ANALYSIS OF THE EXISTING SCIENTIFIC LITERATURE, PRACTICAL APPLICATIONS ARE PROVIDED FOR COACHES.
Reducción de la Anemia en Gestantes a través de una Intervención con Base Comunitaria
Authors: Elías Peñafiel Lourdes , Vía Gladys , Rodríguez Marizol , Tinoco Iris 
Published: January 2017

OBJETIVO: Evaluar el impacto de una intervención preventivo-emocional, basada en la comunidad, para mejorar el conocimiento y el consumo de hierro de las mujeres gestantes con anemia. METODOS: El estudio se realizó en las zonas urbano marginales del Cono Sur de Lima - Peru; se encuestó 76 mujeres anémicas en el 2° trimestre de embarazo, predominantemente jóvenes (50%, 17% adolescentes). La intervención se caracterizó por la participación de las mujeres organizadas en la promoción de la salud de la mujer, a través de la suplementación y monitorización del consumo de hierro, por el conocimiento del perfil sociocultural de las gestantes anémicas y la realización de una intervención en Información, Educación y Comunicación (IEC). RESULTADOS : Existe un alto porcentaje de mujeres con antecedentes de aborto (23%). Algo más de la mitad (51%) de las madres se informaron a través de las promotoras de salud sobre la utilidad del consumo de hierro. Se recuperaron de la anemia 55% de las gestantes, obteniéndose respuesta terapéutica en 45% y fracaso en 17%. CONCLUSION : Se pudo mejorar despues de la intervención en IEC la práctica consciente del consumo de hierro en 97%. El seguimiento periódico y la orientación individual transmitida de manera permanente y adecuada fueron trascendentales.
Cátedra de Cirugía Infantil
Authors: Graña Francisco 
Published: January 2017

Lección inaugural del curso de 1922, Cátedra de Cirugía Infantil, por el Dr. Francisco Graña, Catedrático de Cirugía Infantil y Ortopedia en la Facultad de Medicina de Lima, de la Academia Nacional de Medicina, de la Sociedad Peruana de Cirugía.
Intrapartum Fever and Unexplained Seizures in Term Infants
Authors: Lieberman Ellice , Eichenwald Eric , Mathur Geeta , Richardson Douglas , Heffner Linda , Cohen Amy 
Published: January 2017

Objective.
Early-onset neonatal seizures are a strong predictor of later morbidity and mortality in term infants. Although an association of noninfectious intrapartum fever with neonatal seizures in term infants has been reported, it was based on only a small number of neonates with seizures. We therefore conducted a case control study to investigate this association further.

Methods.
All term infants with neonatal seizures born at Brigham and Women's Hospital between 1989 and 1996 were identified. For this study, cases consisted of all term neonates with a confirmed diagnosis of seizure born after a trial of labor for whom no proximal cause of seizure could be identified. Infants with sepsis or meningitis were excluded. Four controls matched by parity and date of birth were identified for each case. The rate of intrapartum maternal temperature &gt;100.4°F was compared for case infants and controls. Potential confounding was controlled in logistic regression analysis.

Results.
Cases comprised 38 term infants with unexplained seizures after a trial of labor. We identified 152 controls. Infants with seizures were more likely to be born to mothers who were febrile during labor (31.6% vs 9.2%). In almost all cases, the fever developed during labor (94.7% cases, 97.4% controls). At admission, mothers of infants with seizures were not significantly more likely to have factors associated with concern about infection such as a white blood cell count &gt;15 000/mm3 (28.9% vs 19.1%) and premature rupture of the membranes (15.8% vs 17.8%). In a logistic regression analysis controlling for confounding factors, intrapartum fever was associated with a 3.4-fold increase in the risk of unexplained neonatal seizures (odds ratio = 3.4, 95% confidence interval = 1.03–10.9).

Conclusion.
Our data indicate that intrapartum fever, even when unlikely to be caused by infection, is associated with a fourfold increase in the risk of unexplained, early-onset seizures in term infants.
Philadelphia-negatív krónikus Myeloproliferativ Neoplasia Magyarországi Regiszter. Essentialis thrombocythaemiás betegeink adatainak elemzése
Authors: Dombi Péter , Illés Árpád , Demeter Judit , Homor Lajos , Simon Zsófia , Udvardy Miklós , Karádi Éva , Kellner Ádám , Egyed Miklós 
Published: January 2017

Abstract: Introduction: In order to establish and use a national registry, several Hungarian hematology centers collected data of myeloproliferative neoplasia patients. Aim: The recent publication is an analysis of the data of registered essential thrombocythaemic patients. Method: an online electronic registry has been established, using 2008 World Health Organization’s diagnostic criteria and thrombotic risk was evaluated according to Landolfi stratification. Results: Data of 350 essential thrombocythaemic patients from 15 Hungarian hematology centers entered up to the date of June 30, 2015 were used for analysis. Patients were followed up to (median) 6 years. The epidemiologic data (age, gender) and thrombotic events prior and after the diagnosis, were similar to the literature. The thrombotic events of anagrelide treated patient (n = 139) and the hydroxyurea + aspirin treated patients (n = 141) have been compared. The major arterial and venous events were similar between the groups, but there were fivefold less minor arterial and venous events in the anagrelide group (p<0.001). Thrombotic incidence after diagnosis were influenced only by medication and thrombotic events before the diagnosis. Conclusions: Anagrelide significantly decreased the number of patients experiencing minor arterial and minor venous thrombosis, vs hydroxyurea + aspirin. Despite of the treatment the risk of thrombotic events after diagnosis remained high, and was significantly increased in patients with thrombosis before diagnosis. Orv. Hetil., 2017, 158(3), 111–116.
A rákmorbiditás és -mortalitás jelenlegi helyzete a Nemzeti Rákregiszter tükrében
Authors: Kásler Miklós , Ottó Szabolcs , Kenessey István 
Published: January 2017

Abstract: In a previous issue of this journal the authors presented and summarized the basic objectives and tasks of the Hungarian National Cancer Registry positioned in an international environment. The recent publication is a continuation of the previous one. Based on the presentation and analysis of current statistical data, the public health background with the possible risk factors is examined. Considering changes in recent years, the mortality data are relatively stable, although slightly wavering. The trends are promising in some cancers (for example lip and oral cavity, breast, prostate cancers) however. Contrary to the barely changing nature of the total cancer deaths the number of annually reported new cases has increased significantly, which indicates a more effective role in both diagnostics and therapy. In light of the above, it is confirmed that the restructure of the national oncology care system and the European conformation is inevitable. Orv. Hetil., 2017, 158(3), 84–89.
Cardiomyopathiás és ioncsatorna-betegek regisztere: a Szegedi CardioGen Regiszter
Authors: Blazsó Péter , Kákonyi Kornél , Forster Tamás , Sepp Róbert 
Published: January 2017

Abstract: The Szeged cardiomyopathy and ion channel diseases registry aims to establish a representative disease-specific registry based on the recruitment of patients with different cardiomyopathies and ion channel diseases followed at the Cardiology Center, University of Szeged. The registry collects patient data on the main forms of primary cardiomyopathies (hypertrophic, dilated, restrictive, arrhythmogenic right ventricular, left ventricular non-compact, tako-tsubo cardiomyopathy) and ion channel diseases (long QT syndrome, short QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia). Patients with hypertrophic cardiomyopathy (388 patients) make up the largest group of patients in the registry. Patients with dilated cardiomyopathy (310 patients) and patients with the long QT syndrome (111 patients) form two other sizable groups. Analyzed data of the group of patients with hypertrophic cardiomyopathy indicate similar figures with regard to disease related mortality and morbidity and clinical parameters. Orv. Hetil., 2017, 158(3), 101–105.
A coronariarendszer komputertomográfiás vizsgálata – Országos Plakk Regiszter és Adatbázis (OPeRA)
Authors: Bagyura Zsolt , Kolossváry Márton , Merkely Béla , Maurovich-Horvat Pál 
Published: January 2017

Abstract: Introduction and aim: Coronary computer tomography angiography is a unique non-invasive imaging technique with the capability to provide information regarding plaque quantity, burden and structure. A reliable registry is required to use the data of these examinations in research projects. The difficulty is that registries need double data entry simultaneously to the hospital information system. Method: Our registry solves this problem through a structured reporting tool, which generates clinical report and stores all data simultaneously. The automatically generated report is based on international guidelines. Results: Between August 1. 2014 and September 1. 2015 we registered the data of 2866 patients. Coronary plaque was observed in 77.03% of the patients, 33.18% of the plaques were calcified. Severe stenosis was present in 13.71% of the patients. Conclusions: The structured reporting decreases reporting time, eliminates double data entry related errors. Our goal is to initiate a nationwide, unified registry, the National Plaque Registry and Database. Orv. Hetil., 2017, 158(3), 106–110.
A szívinfarktus miatt kezelt betegek ellátása Magyarországon. A Nemzeti Szívinfarktus Regiszter 2015. évi adatainak elemzése
Authors: Jánosi András , Ofner Péter , Al-Maktari Fahmi , Hajkó Erik , Hati Krisztina , Járai Zoltán , Józan-Jilling Mihály , Kiss Róbert Gábor , Lóczi Gerda , Lupkovics Géza , Ruzsa Zoltán , Schmidt Erika , Veress Gábor , Zsifkov Tibor , Merkely Béla 
Published: January 2017

Abstract: The authors summarize the most relevant data of myocardial infarction patients according to the National Myocardial Infarction Registry data base. In 2015 12,681 patients had 12,941 acute myocardial infarctions. Less than half of patients (44.4%) were treated with ST elevation myocardial infarction. National Ambulance Service was the first medical contact of more than half (51.4%) of patients with ST elevation infarction. Prehospital thrombolysis was occasionally done (0.23%), but 91.6% of the patients were treated in hospital with invasive facilities. The median of the ischaemic time (time between onset of symptoms and arrival at the invasive laboratory) was 223 minutes. Most of the patients (94%) with positive coronary arteriography were treated with percutaneous coronary intervention. The 30 day mortality of the whole group was 12.8% vs. 8.6% of patients treated with an invasive procedure. Conclusion: comparing the national and international registry data we conclude that we should analyse and decrease the prehospital delay time to improve the patient care in Hungary. Orv. Hetil., 2017, 158(3), 90–93.
Our experience in gastrointestinal perforations: a retrospective study
Authors: Kemparaj Thammegowda , Narasimhaiah Narasimhamurthy Kadirehalli , Mayigaiah Ravikiran Keragodu 
Published: January 2017

Background: Peritonitis secondary to gastrointestinal perforation is still one of the commonest surgical emergencies in India and is associated with high morbidity and mortality. The present study examines the incidence of various types of gastrointestinal perforations, their complications and the management of patients with postoperative leaks in our surgical unit and compares our findings with those of previous studies performed between 1984 and 2014.Methods: Retrospective study analyzing the case files of all the operated cases of gastrointestinal perforations in a single unit over the last 10 years from September 2005 to August 2015 by open procedure. A total number of 381 cases were studied. All cases with perforative peritonitis, whether spontaneous, infective, traumatic or of neoplastic pathology, were included in the study.Results: Gastrointestinal perforations were common between the ages of 30-50 years; 82% were males. From July to October (rainy seasons) every year a higher number of perforations were noticed; 40% of patients had duodenal, 34% had ileal, 11% appendicular, 6% gastric, 6% jejunal and 3% had colonic perforations. Abdominal pain (100%) and vomiting (81%) were the most common symptoms while tachycardia (50%) and tachypnea (42%) were common signs; 15-20% presented late with features of shock.Conclusions: Gastrointestinal perforations are one of the most common surgical emergencies. Duodenal perforations are most common. Ileal perforations secondary to enteric fever (typhoid) have highest morbidity and mortality. Most of the anastomotic leaks can be treated conservatively. Mortality depends on the general condition of the patient and associated pre-operative comorbidities.
A prospective study on suture ligation of internal hemorrhoids without Doppler guidance for the treatment of symptomatic hemorrhoid disease
Authors: Saxena Pradeep , Bhakuni Yogendra S. 
Published: January 2017

Background: Hemorrhoids or piles are one of the most common afflictions of human being, affecting both sexes & can occur at any age. The aim of the study was to study the effectiveness of suture ligation of hemorrhoids and mucopexy as an outpatient treatment for symptomatic hemorrhoids.Methods: This prospective observational study was carried out in the department of surgery, Gandhi Medical College, Bhopal, Madhya Pradesh, India on 64 adult patients of hemorrhoids treated by suture ligation of hemorrhoid pedicle without Doppler guidance and mucopexy from July 2012 to December 2014. The patients were managed as outpatient or day care cases. The observations and follow up data were recorded and descriptive analysis was done to study the clinical presentation of hemorrhoid disease and effectiveness of hemorrhoid ligation and mucopexy in an ambulatory, outpatient or day care setting.Results: Total 64 patients of hemorrhoids who underwent suture ligation of hemorrhoids and mucopexy were studied. Most of the patients were between 31- 60 years of age (74.28%) with males predominance (64.06%). All the patients in this study had bleeding per rectum as the main symptom. All patients had hemorrhoids in primary 3, 7 or 11 ‘o clock positions and 21 patients (32.8%) had secondary hemorrhoids as well. Majority the patients had 1-3 degree hemorrhoids. However hemorrhoid ligation was also done in 7 patients with fourth degree hemorrhoid who were severely anemic and unfit for surgery due to co morbidities. Over all 82.81% patients were free from symptoms at 1 year follow up after the procedure and only 7.81% of the patients had recurrence of bleeding or prolapse.Conclusions: Hemorrhoid suture ligation with mucopexy is a simple, safe & cost-effective ambulatory treatment for the patients of symptomatic hemorrhoids. Overall the results of hemorrhoid ligation and mucopexy were satisfactory with good control of patients complains.
Prevalence of iodine deficiency among multinodular goiter patients: a South Indian study
Authors: Kerakada Nishad , Manikantan Ganesh , Chisthi Meer M. 
Published: January 2017

Background: Mass iodization of table salt was introduced by the Government of India to treat as well as prevent iodine deficiency problems including goitres. However, even after so many years of introduction of iodized salt, the number of patients reporting with multi nodular goiter to the hospitals in Kerala seems to be high. The coastal districts of Trivandrum and Kollam report especially high prevalence of goitres and subsequently thyroidectomies. The aim of this study was to find the prevalence of iodine deficiency among patients with multi nodular goiter in South Kerala.Methods: This was a cross sectional study of 300 patients admitted with multinodular goitre in the general surgical wards of Government Medical College Trivandrum, Kerala, India. From June 2013 to June 2014, these patients were evaluated clinically and with the investigatory facilities available at this institution. Their urine spot iodine excretion levels were measured at the laboratory of state iodine deficiency control cell, Trivandrum, Kerala, India.Results: Out of the 300 cases, 6 patients were found to have mild iodine deficiency. Mean iodine level was normal at 170 microgram per decilitre. The prevalence of iodine deficiency in multinodular goiter cases studied was found to be 2%.Conclusions: The high prevalence of multinodular goiter cases in Kerala cannot be sited per se as due to iodine deficiency as only 2% of the total number of cases studied had low urine iodine levels. This raises a question whether the salt iodization programme needs to be re-analyzed and possibly re-structured for the state of Kerala.