bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Synthesis of a 4‐Vinyltetrahydrocarbazole by Palladium‐Catalyzed Asymmetric Allylic Alkylation of Indole‐Containing Allylic Carbonates.
Authors: Pignataro Luca , Fiorito Daniele , Vece Vito , Ferraccioli Raffaella , Gennari Cesare 
Published: February 2016

AbstractA detailed investigation is presented concerning the choice of Pd source, PhthalaPhos ligand, solvent, temperature and Pd‐ligand ratio.
ChemInform Abstract: Investigation into the Chemistry of Highly Substituted [(Aminocyclopropyl)methyl]alkoxyamines (3‐Azabicyclo[3.1.0]hexanes).
Authors: Hauck Stefan , Kuepfert Michael , Schoening Kai‐Uwe 
Published: February 2016

AbstractEnamine precursors of type (I) substituted with a morpholine unit are selectively chlorinated as is demonstrated with examples (II) and (III).
ChemInform Abstract: Multicomponent/Palladium‐Catalyzed Cascade Entry to Benzopyrrolizidine Derivatives: Synthesis and Antioxidant Evaluation.
Authors: Miranda Luis D. , Hernandez‐Vazquez Eduardo 
Published: February 2016

AbstractThe protocol combines an Ugi four‐component reaction, an elimination and a Pd‐catalyzed 5‐exo‐trig/5‐exo‐trig cascade carbocyclization to provide the title compounds.
ChemInform Abstract: Ugi/Himbert Arene/Allene Diels—Alder Cycloaddition to Synthesize Strained Polycyclic Skeleton.
Authors: Cheng Guangsheng , He Xiang , Tian Lumin , Chen Jiawen , Li Chunju , Jia Xueshun , Li Jian 
Published: February 2016

AbstractThe protocol represents the first example of combining a multicomponent Ugi‐reaction and an intramolecular phenyl/allene Diels—Alder cycloaddition, thus providing an easy access to the complex polycyclic skeleton (V) and (VIII).
ChemInform Abstract: Synthesis of Chiral Pyrazoles: A 1,3‐Dipolar Cycloaddition/[1,5] Sigmatropic Rearrangement with Stereoretentive Migration of a Stereogenic Group.
Authors: Perez‐Aguilar M. Carmen , Valdes Carlos 
Published: February 2016

AbstractIn situ generated chiral diazo compounds undergo 1,3‐dipolar cycloaddition reactions with alkynes followed by stereoretentive migration of the stereogenic group.
ChemInform Abstract: Synthesis of Pyrazolo[5,1‐a]isoquinolines and 8‐Methylenepyrazolo[5,1‐a]isoindoles via Regioselective C—C Coupling and Alkyne Hydroamination.
Authors: Fan Xuesen , Yan Meng , Wang Yuanyuan , Zhang Xinying 
Published: February 2016

AbstractSonogashira coupling of terminal alkynes with bromophenylpyrazoles, generated in situ by condensation of the corresponding butadienones with hydrazine hydrate, and subsequent 6‐endo intramolecular alkyne hydroamination leads to pyrazoloisoquinolines.
ChemInform Abstract: Diversity‐Oriented Heterocyclic Synthesis Using Divergent Reactivity of N‐Substituted Iso(thio)cyanates.
Authors: Vincent‐Rocan Jean‐Francois , Derasp Joshua S. , Beauchemin Andre M. 
Published: February 2016

AbstractThe microwave‐assisted triethylamine‐catalyzed reaction of hydrazone‐based N‐isocyanate precursors (I) and (IV) with propargylamines (II) leads to imidazolones (III) and (V), respectively.
ChemInform Abstract: Synthesis of New 2‐Aminoimidazolones with Antiproliferative Activity via Base Promoted Amino‐β‐Lactam Rearrangement.
Authors: Drazic Tonko , Vazdar Katarina , Vazdar Mario , Dakovic Marijana , Mikecin Ana‐Matea , Kralj Marijeta , Malnar Martina , Hecimovic Silva , Habus Ivan 
Published: February 2016

AbstractAn interesting conversion of amino‐β‐lactam guanidines (III) to imidazolones of type (IV) and (V) is described.
ChemInform Abstract: C—H Arylation and Alkenylation of Imidazoles by Nickel Catalysis: Solvent‐Accelerated Imidazole C—H Activation.
Authors: Muto Kei , Hatakeyama Taito , Yamaguchi Junichiro , Itami Kenichiro 
Published: February 2016

AbstractThe first Ni‐catalyzed arylation of benzimidazoles (I) with aryl carbamates (II) leads to desired 2‐arylbenzimidazoles (III).
ChemInform Abstract: Gold‐Catalyzed Tandem Reactions of Amide—Aldehyde—Alkyne Coupling and Cyclization‐Synthesis of 2,4,5‐Trisubstituted Oxazoles.
Authors: Querard Pierre , Girard Simon A. , Uhlig Nick , Li Chao‐Jun 
Published: February 2016

AbstractThe first Au(I)‐catalyzed synthesis of highly substituted oxazole derivatives via one‐pot, multicomponent reaction of amides, alkynes, and aldehydes is developed.
ChemInform Abstract: Silyl Nitronate Cycloadditions Catalyzed by Cu(II)‐Bisoxazoline.
Authors: Dong Li , Geng Caiwei , Jiao Peng 
Published: February 2016

AbstractThe 1,3‐dipolar cycloaddition of silyl nitronates (II) with α,β‐unsaturated carboxamides (III) and (V) affords chiral isoxazolines (IV) and (VI), resp., in high yields, high enantioselectivities, and complete diastereoselectivities.
ChemInform Abstract: Direct Access to 1,4‐Disubstituted 1,2,3‐Triazoles Through Organocatalytic 1,3‐Dipolar Cycloaddition Reaction of α,β‐Unsaturated Esters with Azides.
Authors: Li Wenjun , Zhou Xiao , Luan Yepeng , Wang Jian 
Published: February 2016

AbstractDBU‐catalyzed 1,3‐dipolar cycloaddition of α,β‐unsaturated ester (I) to azides (II) gives 1,4‐disubstituted 1,2,3‐triazoles (III) in good yields.
ChemInform Abstract: Allyl‐Assisted, Cu(I)‐Catalyzed Azide—Alkyne Cycloaddition/Allylation Reaction: Assembly of the [1,2,3]Triazolo‐4,5,6,7‐tetrahydropyridine Core Structure.
Authors: Deng Xiaohu , Liang Jimmy , Allison Brett B. , Dvorak Curt , McAllister Heather , Savall Brad M. , Mani Neelakandha S. 
Published: February 2016

AbstractThe one‐pot, three‐component synthesis of 1,4‐disubstituted 5‐allyl‐triazoles (IV), (VI) and (VIII) is reported.
ChemInform Abstract: SNAr versus Buchwald—Hartwig Amination/Amidation in the Imidazo[2,1‐b][1,3,4]thiadiazole Series.
Authors: Copin Chloe , Massip Stephane , Leger Jean‐Michel , Jarry Christian , Buron Frederic , Routier Sylvain 
Published: February 2016

AbstractAmination of the heterocyclic skeleton is first carried out under conditions A).
ChemInform Abstract: Carbocation Catalysis: Oxa‐Diels—Alder Reactions of Unactivated Aldehydes and Simple Dienes.
Authors: El Remaily Mahmoud Abd El Aleem Ali Ali , Naidu Veluru Ramesh , Ni Shengjun , Franzen Johan 
Published: February 2016

AbstractThe versatility of the trityl cation as an efficient Lewis acid organocatalyst is demonstrated in the title process.
ChemInform Abstract: Synthesis of Substituted Tetrahydropyrans and Tetrahydrofurans via Intramolecular Hydroalkoxylation of Alkenols.
Authors: Sultana Sabera , Devi Ngangbam Renubala , Saikia Anil K. 
Published: February 2016

AbstractThe process is highly atom‐economic and compatible with a series of functional groups.
ChemInform Abstract: Expedient Synthesis of Tricyclic Benzopyran‐2‐ones via N‐Heterocyclic Carbene Catalyzed Annulation of Enals to α‐Methylene Cycloalkanones.
Authors: Venkata Mani Padmaja D. , Sinu C. R. , Krishnan Jagadeesh , Paul Rony Rajan , Varughese Sunil , Seetha Lakshmi K. C. , Nair Vijay 
Published: February 2016

AbstractThe reaction succeeds using aryl, hetaryl, and alkyl substituted enals.
ChemInform Abstract: Intramolecular Direct Arylation of 3‐Halo‐2‐pyrones and 2‐Coumarins.
Authors: Nolan Marie‐T. , Pardo Leticia M. , Prendergast Aisling M. , McGlacken Gerard P. 
Published: February 2016

AbstractIntramolecular coupling of 3‐halo‐2‐pyrones (I) and (III) by activation of a pyrone C—Br or C—Cl bond and a phenoxy C—H bond is reported.
ChemInform Abstract: Gold Nanoparticles Supported on a Layered Double Hydroxide as Efficient Catalysts for the One‐Pot Synthesis of Flavones.
Authors: Yatabe Takafumi , Jin Xiongjie , Yamaguchi Kazuya , Mizuno Noritaka 
Published: February 2016

AbstractFlavones are prepared from methylphenylketones and aryl aldehydes or benzyl alcohols under oxidizing conditions.
ChemInform Abstract: Base‐Mediated Cyclocondensation of Salicylaldehydes and 2‐Bromoallyl Sulfones for the Synthesis of 3‐Sulfonylchromene Derivatives and Their Regioselective Friedel—Crafts Heteroarylation Reactions.
Authors: Kumar Anand , Thadkapally Srinivas , Menon Rajeev S. 
Published: February 2016

AbstractA transition metal‐free, vinylic bromide displacement reaction of bromoallyl sulfones (II) with phenolate nucleophiles is reported.
ChemInform Abstract: Cobalt(III)‐Catalyzed C—N/N—O Functionalizations: Isohypsic Access to Isoquinolines.
Authors: Wang Hui , Koeller Julian , Liu Weiping , Ackermann Lutz 
Published: February 2016

AbstractVariously functionalized arylalkyl and hetarylalkyl oximes react with diaryl‐ and dialkyl‐ alkynes to form isoquinolines in high yields.
ChemInform Abstract: Cobalt(III)‐Catalyzed Dehydrative [4 + 2] Annulation of Oxime with Alkyne by C—H and N—OH Activation.
Authors: Sen Malay , Kalsi Deepti , Sundararaju Basker 
Published: February 2016

AbstractThe scalable reaction has a broad substrate scope, thus tolerating variously functionalized arylalkyl and hetarylalkyl oximes as well as diaryl and dialkyl alkynes.
ChemInform Abstract: Copper(II)‐Mediated Aerobic Synthesis of Imidazo[1,2‐a]pyridines via Cascade Aminomethylation/Cycloisomerization of Alkynes.
Authors: Rassokhina Irina V. , Shirinian Valerii Z. , Zavarzin Igor V. , Gevorgyan Vladimir , Volkova Yulia A. 
Published: February 2016

AbstractThe utility of this method is demonstrated in the synthesis of anxiolytic drug alpidem (XI).
ChemInform Abstract: Palladium‐Catalyzed ortho‐Acylation of 6‐Anilinopurines/Purine Nucleosides via C—H Activation.
Authors: Allu Srinivasarao , Swamy K. C. Kumara 
Published: February 2016

AbstractVarious aldehydes or α‐oxocarboxylic acids are used as acylating source.
ChemInform Abstract: A Highly Efficient Copper(I)‐Catalyzed Cascade Reaction of o‐Alkenylphenyl Isothiocyanates with Isocyanides Leading to 5H‐Benzo[d]imidazo[5,1‐b][1,3]thiazines.
Authors: Hao Wenyan , Huang Jian , Jie Shanshan , Cai Mingzhong 
Published: February 2016

AbstractSubstrates bearing an acrylate or acrylonitrile side chain can be used in the highly efficient preparation of the desired heterocyclic scaffold.
ChemInform Abstract: Tandem C—O and C—N Bonds Formation Through O‐Arylation and [3,3]‐Rearrangement by Diaryliodonium Salts: Synthesis of N‐Aryl Benzo[1,2,3]triazin‐4(1H)‐one Derivatives.
Authors: Shi Wei‐Min , Ma Xiao‐Pan , Pan Cheng‐Xue , Su Gui‐Fa , Mo Dong‐Liang 
Published: February 2016

AbstractThe reaction proceeds regioselectively and with remarkable chemoselectivity when unsymmetric diaryliodonium triflates are used.
ChemInform Abstract: Palladium‐Catalyzed Iterative C—H Bond Arylations: Synthesis of Medium‐Size Heterocycles with a Bridgehead Nitrogen Atom.
Authors: Hagui Wided , Yuan Kedong , Besbes Neji , Srasra Ezzeddine , Soule Jean‐Francois , Doucet Henri 
Published: February 2016

AbstractPd‐catalyzed direct desulfinative C—H bond arylation of pyrroles (I) and (XIII) with sulfonyl chlorides gives mono‐ and diarylated products.
ChemInform Abstract: Synthesis of Three New Tricyclic Ring Systems: Pyrrolotriazepines Condensed with an Imidazole, a Triazole, or a Tetrazole Ring.
Authors: Milen Matyas , Foeldesi Tamas , Dancso Andras , Simig Gyula , Volk Balazs 
Published: February 2016

AbstractStarting from one previously developed key intermediate simple preparations of the three new title ring systems are elaborated which tolerate various alkyl and (hetaryl)aryl substituents.
ChemInform Abstract: Rhodium(II)‐Catalyzed Cycloaddition Reactions of Non‐classical 1,5‐Dipoles for the Formation of Eight‐Membered Heterocycles.
Authors: Lee Dong Jin , Ko Donguk , Yoo Eun Jeong 
Published: February 2016

AbstractA new type of [5 + 3] cycloaddition between pyridinium zwitterion 1,5‐dipole equivalents and enol diazoacetates is developed for the synthesis of eight‐membered heterocycles.
ChemInform Abstract: Gold‐Catalyzed Intramolecular Cyclization of N‐Propargylic β‐Enaminones for the Synthesis of 1,4‐Oxazepine Derivatives.
Authors: Goutham Kommuru , Ashok Kumar Desamala , Suresh Surisetti , Sridhar Balasubramanian , Narender Ravirala , Karunakar Galla V. 
Published: February 2016

AbstractIn this novel approach using AuCl3/AgSbF6 as catalytic system, the title substrates undergo regioselective 7‐exo‐dig cyclization to give the title compounds in good to high yields.
ChemInform Abstract: Facile Synthesis and Properties of 2‐λ5‐Phosphaquinolines and 2‐λ5‐Phosphaquinolin‐2‐ones.
Authors: Vonnegut Chris L. , Shonkwiler Airlia M. , Khalifa Muhammad M. , Zakharov Lev N. , Johnson Darren W. , Haley Michael M. 
Published: February 2016

AbstractThe title heterocycles can serve as carbostyril mimics with applications for pharmaceuticals, or as novel switchable fluorophores.
ChemInform Abstract: Triphenylphosphine/2,3‐Dichloro‐5,6‐dicyanobenzoquinone (PPh3/DDQ) System for Conversion of Alcohols and Thiols into Trialkyl Phosphonates.
Authors: Iranpoor Nasser , Firouzabadi Habib , Rajabi Moghadam Khashayar , Etemadi‐Davan Elham 
Published: February 2016

AbstractAliphatic (Ia) and benzylic alcohol (Ic) as well as their analogous thiols are subjected to the reaction with phosphites (IIa)/(IIc) under optimized conditions A) to produce synthetically important phosphonates.
ChemInform Abstract: Novel Cycloartane Triterpenoids from the Nepal Native Plant Caragana sukiensis.
Authors: Mandal Reeta , Siva Bandi , Phani Babu V. S. , Suresh Babu K. , Jagadeesh B. , Ranjit Rosa , Shrestha Kanti , Gewali Mohan Bikram 
Published: February 2016

AbstractThree new cycloartane triterpenoids, sukienside A—C, are isolated from the aerial parts of Caragana sukiensis.
ChemInform Abstract: Sesquiterpenes from Carpesium macrocephalum Inhibit Candida albicans Biofilm Formation and Dimorphism.
Authors: Xie Chunfeng , Sun Lingmei , Meng Linghao , Wang Meicheng , Xu Jing , Bartlam Mark , Guo Yuanqiang 
Published: February 2016

Abstract4‐(2‐Methylbutyryl)‐4H‐tomentosin (I), a new xanthanolide from the whole plant of Carpesium macrocephalum, is isolated along with nine known sesquiterpenes.
ChemInform Abstract: Cytotoxic Constituents from Vietnamese Marine Sponge Haliclona oculata (Linnaeus, 1759).
Authors: Van Kiem Phan , Thi Viet Thanh Nguyen , Thi Thuy Hang Dan , Thi Cuc Nguyen , Xuan Nhiem Nguyen , Hai Yen Pham , Le Tuan Anh Hoang , Huu Tai Bui , Thi Thao Do , Van Minh Chau 
Published: February 2016

AbstractFive steroids and two brominated lipids are isolated from the title sponge.
ChemInform Abstract: Enantioselective Synthesis of‐α‐(Uracil‐5‐yl)glycine Derivatives and Their Racemization‐Free Incorporation into a Model Peptide.
Authors: Weckenmann Nicole M. , Nachtsheim Boris J. 
Published: February 2016

AbstractTarget compounds (II) are prepared with excellent enantioselectivity in the presence of a D‐hydantoinase.
ChemInform Abstract: Synthesis of New Diketopiperazines, Thiolation to Thiodiketopiperazines, and Examination of Their ROS‐Generating Properties.
Authors: Zhong Sabilla , Wandler Angela E. E. , Schepers Ute , Nieger Martin , Braese Stefan 
Published: February 2016

AbstractA broad spectrum of symmetrical and unsymmetrical diketopiperazines is prepared from 9 optically pure amino acids.
ChemInform Abstract: Isolation and Quantification of Six Cardiac Glycosides from the Seeds of Thevetia peruviana Provide a Basis for Toxological Survey.
Authors: Kohls Sarah , Scholz‐Boettcher Barbara M. , Teske Joerg , Rullkoetter Juergen 
Published: February 2016

AbstractIn order to support toxicological assessment of poisoning from the ingestion of plant material containing thevetia cardiac glycosides, a new isolation method is reported for thevetia glycosides from the seeds of the Yellow Oleander with yellow and orange flowers, respectively, using accelerated solvent extraction.
ChemInform Abstract: Tyrokeradines G and H, New Bromotyrosine Alkaloids from an Okinawan Verongid Sponge.
Authors: Kubota Takaaki , Watase Shinya , Sakai Kanae , Fromont Jane , Gonoi Tohru , Kobayashi Jun'ichi 
Published: February 2016

AbstractTyrokeradines G (Ia) and H (Ib), two novel bromotyrosine alkaloids from an Okinawan marine sponge, show antifungal activities.
ChemInform Abstract: Haenamindole, an Unusual Diketopiperazine Derivative from a Marine‐Derived Penicillium sp. KCB12F005.
Authors: Jang Jae‐Hyuk , et al.  
Published: February 2016

AbstractHaenamindole (I) possesses benzyl‐hydroxypiperazindione and phenyl‐pyrimidoindole ring systems in the molecule and shows no cytotoxic activities against Hep‐3B, HeLa, K562, and HL60 cell lines and no antimicrobial activities against Escherichia coli, Bacillus cereus, Staphylococcus aureus, and Salmonella enteritidis.
ChemInform Abstract: Constituents of the Seeds of Cassia tora with Inhibitory Activity on Soluble Expoxide Hydrolease.
Authors: Lee Ga Young , Kim Jang Hoon , Choi Seung‐Kook , Kim Young Ho 
Published: February 2016

AbstractA new anthraquinone derivative, 7‐methoxy‐obtusifolin (I), is isolated from the seeds of Cassia tora along with fifteen known compounds.
ChemInform Abstract: Bioactive Oxygen‐Bridged Cyclooctadienes from Endophytic Fungus Phomopsis sp. BCC 45011.
Authors: Kornsakulkarn Jittra , Somyong Wiwat , Supothina Sumalee , Boonyuen Nattawut , Thongpanchang Chawanee 
Published: February 2016

AbstractIn addition to ten known oxygen‐bridged cyclooctadienes five new derivatives of the latter, phomoxydienes A—C (Ia—c) and dithiorelones (IIa,b) were isolated from title fungus.
ChemInform Abstract: Cytotoxic and Antiviral Tetramic Acid Derivatives from the Deep‐Sea‐Derived Fungus Trichobotrys effuse DFFSCS021.
Authors: Sun Yu‐Lin , Wang Jie , Wang Yi‐Fei , Zhang Xiao‐Yong , Nong Xu‐Hua , Chen Mao‐Yun , Xu Xin‐Ya , Qi Shu‐Hua 
Published: February 2016

AbstractSix new compounds, Trichobotrysins A—F (I)—(III), are isolated from the title fungus.
ChemInform Abstract: Selective Extraction and in situ Reduction of Precious Metal Salts from Model Waste to Generate Hybrid Gels with Embedded Electrocatalytic Nanoparticles.
Authors: Okesola Babatunde O. , Suravaram Sindhu K. , Parkin Alison , Smith David K. 
Published: February 2016

AbstractA hydrogel based on 1,3:2,4‐dibenzylidenesorbitol, modified with acyl hydrazides extracts selectively gold/silver ions from model waste water containing Ni2+, Cu2+, Zn2+, Fe2+, Pt2+, Pd2+, Au3+, and Ag+ ions.
ChemInform Abstract: Phase‐Programmed Nanofabrication: Effect of Organophosphite Precursor Reactivity on the Evolution of Nickel and Nickel Phosphide Nanocrystals.
Authors: Andaraarachchi Himashi P. , Thompson Michelle J. , White Miles A. , Fan Hua‐Jun , Vela Javier 
Published: February 2016

AbstractThe preparation of metallic Ni and nickel phosphide nanocrystals is used to systematically study the structure—reactivity relationship of commercially available organophosphite precursors (P(OR)3, R: alkyl or aryl).
ChemInform Abstract: Antibacterial Activity of Novel Cu2ZnSnS4 Nanoparticles Against Pathogenic Strains.
Authors: Kumar R. Saravana , Maddirevula Sateesh , Easwaran Maheswaran , Dananjaya S. H. S. , Kim Moon‐Deock 
Published: February 2016

AbstractHollow tubular Cu2ZnSnS4 (CZTS) particles are prepared by heating an ethylene glycol solution of CuCl2, ZnCl2, SnCl4, and thiourea in a molar ratio of 2:1:1:4.5 (215 °C, 6 h).
ChemInform Abstract: Tetrathiafulvalene‐Based Radical Cation Salts with Transition Metal Bis(dicarbollide) Anions
Authors: Bregadze Vladimir I. , Dyachenko Oleg A. , Kazheva Olga N. , Kravchenko Andrey V. , Sivaev Igor B. , Starodub Vladimir A. 
Published: February 2016

AbstractReview: [data on their synthesis, crystal structure, electronic and magnetic properties47 refs.
ChemInform Abstract: Advances in the Development of Pyridinone Derivatives as Non‐Nucleoside Reverse Transcriptase Inhibitors
Authors: Vite‐Caritino Hugo , Mendez‐Lucio Oscar , Reyes Hector , Cabrera Alberto , Chavez Daniel , Medina‐Franco Jose L. 
Published: February 2016

AbstractReview: 43 refs.
ChemInform Abstract: Baccharis (Asteraceae): Chemical Constituents and Biological Activities
Authors: Ramos Campos Francinete , Bressan Jaqueline , Godoy Jasinski Vanessa Cristina , Zuccolotto Tatiana , da Silva Luiz Eduardo , Bonancio Cerqueira Leticia 
Published: February 2016

AbstractReview: 162 refs.
ChemInform Abstract: Perovskite Solar Cells: Influence of Hole Transporting Materials on Power Conversion Efficiency
Authors: Ameen Sadia , Rub Malik Abdul , Kosa Samia A. , Alamry Khalid A. , Akhtar M. Shaheer , Shin Hyung‐Shik , Seo Hyung‐Kee , Asiri Abdullah M. , Nazeeruddin Mohammad Khaja 
Published: February 2016

AbstractReview: 89 refs.
ChemInform Abstract: Artificial Photosynthesis at Dynamic Self‐Assembled Interfaces in Water
Authors: Hansen Malte , Troppmann Stefan , Koenig Burkhard Koenig Burkhard 
Published: February 2016

AbstractReview: applications of micellar and vesicular microheterogeneous systems for solar energy conversion by photosensitized water oxidation and hydrogen generation; 44 refs.
ChemInform Abstract: Review of Carbazole Based Conjugated Molecules for Highly Efficient Organic Solar Cell Application.
Authors: Sathiyan Govindasamy , Sivakumar E. K. T. , Ganesamoorthy Ramasamy , Thangamuthu Rangasamy , Sakthivel Pachagoundar 
Published: February 2016

AbstractReview: 87 refs.
ChemInform Abstract: Nanowire Chemical/Biological Sensors: Status and a Roadmap for the Future
Authors: Fennell John F. Jr. , Liu Sophie F. , Azzarelli Joseph M. , Weis Jonathan G. , Rochat Sebastien , Mirica Katherine A. , Ravnsbaek Jens B. , Swager Timothy M. 
Published: February 2016

AbstractReview: 251 refs.
A sequential scaled pairwise selection approach to edge detection in nonparanormal graphical models
Authors: Jiang Yiwei , Chen Zehua 
Published: February 2016

AbstractWe deal with the problem of edge detection in high‐dimensional nonparanormal graphical models. A nonparanormal graphical model is first transformed into a Gaussian graphical model. Then a sequential scaled pairwise selection (SSPS) method which we propose is applied to the transformed model. The SSPS method is a neighbourhood detection approach which makes use of conditional regression models. First the response vector in each individual conditional regression model is scaled, then the response vectors are pooled together to form a single model. The features in this single model are selected pairwise by a sequential procedure, which reflects the intrinsic symmetry of the edges. At each step of the procedure, the current residual vector is projected into the space spanned by each pair of columns of the design matrix which correspond to the symmetric edges, and the selected set of edges is then augmented by the pair with the largest projection norm. The extended BIC (EBIC) is used as the stopping rule for the sequential procedure. The selection consistency of the SSPS method is established. Simulation studies and the analysis of a real data set are carried out to compare the SSPS method with other existing methods. The simulation studies demonstrate that the SSPS method outperforms the other methods. In addition, the SSPS method is computationally more appealing. The Canadian Journal of Statistics 44: 25–43; 2016 © 2016 Statistical Society of Canada
Double Linear Gradient Biointerfaces for Determining Two‐Parameter Dependent Stem Cell Behavior
Authors: Kühn Philipp T. , Zhou Qihui , van der Boon Torben A. B. , Schaap‐Oziemlak Aneta M. , van Kooten Theo G. , van Rijn Patrick 
Published: February 2016

AbstractTwo‐parameter contributions of stiffness and wettability display altered behavior of hBM‐MSCs as compared to solely investigating the wettability of the biointerface with a homogenous stiffness. The importance of double parameter influence is identified by using newly developed double linear wettability–stiffness gradients. The interfaces show that substrate stiffness can influence cell adhesion and spreading both positively and negatively in combination with wettability. This effect is validated by decoupling the stiffness gradient using a wettability gradient composed of a monolayer on glass ensuring a homogenous stiffness.