bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radioligand therapy in the therapeutic strategy for patients with gastro-entero-pancreatic neuroendocrine tumors: a consensus statement from the Italian Association for Neuroendocrine Tumors (Itanet), Italian Association of Nuclear Medicine (AIMN), Italian Society of Endocrinology (SIE), Italian Association of Medical Oncology (AIOM).
Authors: Panzuto Francesco , Albertelli Manuela , De Rimini Maria Luisa , Rizzo Francesca Maria , Grana Chiara Maria , Cives Mauro , Faggiano Antongiulio , Versari Annibale , Tafuto Salvatore , Fazio Nicola , Colao Annamaria , Scalorbi Federica , Ferone Diego , Cinieri Saverio , Maccauro Marco 
Published: October 2024

Abstract

Purpose
This paper outlines the consensus of the Italian Association for Neuroendocrine Tumors(Itanet), the Italian Association of Nuclear Medicine (AIMN), the Italian Society of Endocrinology (SIE), and the Italian Association of Medical Oncology (AIOM) on treating neuroendocrine neoplasms (NENs)with radioligand therapy (RLT).

Methods
A list of 10 questions regarding using RLT ingastroenteropancreatic neuroendocrine tumors (GEP-NETs) was addressed after a careful review of theavailable literature. compiling information from the MEDLINE database, augmented with expert opinionsand recommendations, aligns with the latest scientific research and the author’s extensive knowledge.The recommendations are evaluated using the GRADE system, showcasing the level of evidence andthe strength of the recommendations.

Results and Conclusions
Specifically, this paper focuses on thesubcategories of well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) thatexpress somatostatin receptors and are considered suitable for RLT, according to internationalguidelines.
Nutritional aspects in neuroendocrine neoplasms. bridging the gap between dietary interventions and cancer care strategies: a scoping review
Authors: Massironi Sara , Panzuto Francesco , Zilli Alessandra , Rinzivillo Maria , Ciliberto Ambra , Romano Elena , Danese Silvio , Laviano Alessandro 
Published: October 2024

Abstract

Purpose
Neuroendocrine neoplasms (NENs) represent heterogeneous tumors arising from neuroendocrine cells in different organs. Despite growing interest in the nutritional aspects of NEN management, research in this area is limited. Aim of this review is to summarize the current state of knowledge, highlight research gaps, and underscore the significance of nutrition in the comprehensive care of NEN patients.

Methods
We conducted an extensive bibliographic search focusing on studies (including retrospective and prospective studies, systematic reviews, case series, and guidelines) exploring the relationship between nutritional assessments, dietary interventions, micronutrient deficiencies, and their impact on NEN outcomes.

Results
Significant gaps exist in current research, particularly in understanding the specific nutritional needs of NEN patients and how tailored nutritional interventions can improve clinical outcomes. Evidence suggests that a high-fat Western diet may promote the growth of NEN, while a Mediterranean diet may help lower insulin levels and strengthen the immune system, potentially preventing tumor development. The ketogenic diet and intermittent fasting may also have positive impacts. Addressing common micronutrient deficiencies, such as vitamin D and niacin, is crucial to mitigate disease progression. There’s a crucial need for future studies to include a comprehensive nutritional assessment incorporating patient-reported outcomes, to fully capture the impact of nutritional strategies.

Conclusion
Nutritional management, an important but under-researched facet of NEN treatment, significantly improves patients’ quality of life and survival. Integrating nutrition into personalized cancer care is essential, highlighting the role of nutritional strategies in optimizing patient outcomes.
Electrochemical characterization of TiO2 nanotubes formed on Ti6Al4V manufactured by PBF-EB or forging
Authors: Vásquez F. A. , Aguirre Ocampo Robinson , Bedoya Nicolás , Zuleta Gil Alejandro A. , Botero Carlos , Gómez Maryory , Castaño Juan G. , Tamayo José A. 
Published: October 2024

AbstractThis study introduces the anisotropy effect of Ti6Al4V substrate obtained by electron beam melting (PBF-EB) on the anodizing process, revealing its capacity to induce anisotropic TiO2 nanotubes. Highly organized TiO2 nanotubes are formed on Ti6Al4V substrates produced through PBF-EB or forging, with the PBF-EB cross-orientation displaying superior nanotube growth due to enhanced catalytic activity. Morphological and electrochemical characterizations underscore the significant influence of substrate orientation and anodizing voltage on nanotube growth and corrosion resistance. PBF-EB-cross orientation at 30 V exhibits a thicker and more homogeneous nanotube layer, resulting in improved film resistance and substantially lower corrosion rates compared to forged substrates. The electrochemically calculated nanotube film thickness aligns with microscopic analyses, emphasizing the importance of a homogenous and resistive nanotube coating for effective corrosion control.
Regimes of Self-Presentation and Digital Street Credibility: How Urban Youth Negotiate Online and Offline Visibility
Authors: Balleys Claire , Tadorian Marc , Colombo Annamaria 
Published: October 2024

AbstractDrawing on a study of how young people in Switzerland appropriate urban public space, this article explores what we term “regimes of self-presentation” among youth in both online and offline spaces. We address issues of privacy and power that help shape such regimes by applying an expanded notion of street credibility that encompasses digital practices. Our concept of “digital street credibility” recognizes how, in today’s world, any social or cultural practices engaged in by youth have two potential types of audiences. One is physically present, consisting of other users of urban public space. The second audience is media-based, consisting of people with access to live or prerecorded digital content captured on smartphones and shared on social networks. This situation has forced young people to develop new and specific social conventions governing self-presentation. The article highlights the complex and perilous nature of visibility management. Where privacy and power relations are concerned, a very thin line separates behavior that enhances an individual’s social status from actions considered “embarrassing” or “cringe.” Our results show how, in the streets as well as online, acceptable forms of visibility are determined on the basis of digital street credibility. These findings suggest a need to reconsider young people’s understanding of privacy, as it relates to their leisure activities in urban and digital spaces.
Analysis of policy changes for Yangtze River Basin governance from 1980 to 2022—based on semantic analysis method and punctuated equilibrium theory
Authors: Li Hao , Li Meng , Qin Yi , Ji Meiduo 
Published: October 2024

AbstractThe governance policies have a prominent impact on the development and regional planning of the Yangtze River Basin, a key region for China to achieve modernization. Taking the public policy documents issued by China’s central government for the Yangtze River Basin from 1980 to 2022 as the research object, this paper introduces the NLP (Natural Language Processing) technology and semantic analysis methods to carry out quantitative research on policies. This study first examines the textual connotations of the policies and the characteristics of the policy changes based on the LDA (Latent Dirichlet Allocation) model to determine how policy changes occur for the governance of the Yangtze River Basin. Using the punctuated equilibrium theory, it then conducts two case studies in which the implications of specific major events are analyzed in depth. Research has shown that the changes in governance policies for the Yangtze River Basin are characterized by gradual changes and intermittent mutation, roughly divided into three stages: the stage of reform and development, the stage of transition, and the stage of prioritizing ecological conservation and green development. Moreover, such changes jointly result from three factors: the major events, the focus of public opinions, and the care of the central government.
Passive Source Reverse Time Migration Based on the Spectral Element Method
Authors: He Bin , Chen Yu , Lei Ting , Lumley David , Liu Qinya , Takeuchi Nozomu , Kawakatsu Hitoshi , Zhu Hejun 
Published: October 2024

AbstractIncreasing deployment of dense arrays has facilitated detailed structure imaging for tectonic investigation, hazard assessment and resource exploration. Strong velocity heterogeneity and topographic changes have to be considered during passive source imaging. However, it is quite challenging for ray‐based methods, such as Kirchhoff migration or the widely used teleseismic receiver function, to handle these problems. In this study, we propose a 3‐D passive source reverse time migration strategy based on the spectral element method. It is realized by decomposing the time reversal full elastic wavefield into amplitude‐preserved vector P and S wavefields by solving the corresponding weak‐form solutions, followed by a dot‐product imaging condition to get images for the subsurface structures. It enables us to use regional 3‐D migration velocity models and take topographic variations into account, helping us to locate reflectors at more accurate positions than traditional 1‐D model‐based methods, like teleseismic receiver functions. Two synthetic tests are used to demonstrate the advantages of the proposed method to handle topographic variations and complex velocity heterogeneities. Furthermore, applications to the Laramie array data using both teleseismic P and S waves enable us to identify several south‐dipping structures beneath the Laramie basin in southeast Wyoming, which are interpreted as the Cheyenne Belt suture zone and agree with, and improve upon previous geological interpretations.
Propagation of Free Infragravity Waves Generated at Distant Beaches
Authors: Matsuba Yoshinao , Roelvink Dano , van Dongeren Ap 
Published: October 2024

AbstractInfragravity (IG) waves are important drivers of extreme run‐up, morphological changes, and seiches. While locally forced IG waves have been extensively investigated, recent studies have revealed the significance of free IG waves generated on distant beaches. This study focuses on free IG waves generated at a coast facing southeast in Japan during the passage of a typhoon. The relationship between incident short waves and free IG waves as well as their contributions to nearshore IG waves, in particular to seiches in a small port, are analyzed using unique measurement data and numerical experiments. During the typhoon passage, more than 75% of the observed IG wave energy originates from free IG waves at an observatory located at a depth of 23 m, and their peak direction is alongshore. Six‐year measurement data demonstrate that peak directions of free IG waves strongly depend on the incident wave angles of short waves and that swells from the south generate alongshore propagating free IG waves. A numerical model can reproduce the alongshore propagating free IG waves accurately when using a large computational domain. Moreover, numerical experiments performed using the model demonstrate that the alongshore propagating free IG waves are IG waves reflected from distant beaches. The free IG waves from distant beaches are small outside the port, but seiches in the port are amplified by more than 10%. The relationship between seiches and incoming free IG waves is further discussed based on the numerical experiments.
Paired X‐Ray Micro CT Scanning and Individual Foraminifera Isotopic Analysis Reveal (De)coupled Changes in Carbonate Preservation and Temperature
Authors: Jana Debadrita , Torres Mark , Evans Kory , Jayan Ammoose K. , Thirumalai Kaustubh 
Published: October 2024

AbstractThe composition and preservation state of biogenic carbonate archives, such as foraminiferal tests, record ocean chemistry during the lifetime of the organism and post‐depositional changes in ambient conditions via carbonate compensation. Depending upon the specific paleoclimate proxy, post‐depositional processes, including dissolution, may alter original paleoenvironmental signals captured by the foraminifer's test composition. Accordingly, quantifying dissolution independent of geochemical measurements can improve proxy interpretation. Developing independent tools may also be useful for investigating whether changes in paleoclimatic conditions are associated with changes in seawater carbonate chemistry. Such approaches can be improved further if they are applied to individual foraminiferal tests, as specimen‐to‐specimen differences can record higher‐frequency environmental changes compared to conventional bulk‐scale analyses. Here, we combine individual foraminiferal carbon and oxygen isotopic analyses (IFA) with X‐ray MicroCT Scanning to generate paired analyses of test density (a proxy for the extent of post‐depositional dissolution) and isotopic composition. As a proof‐of‐concept application of this approach, we analyze Globigerina bulloides tests from both coretop and latest Miocene/earliest Pliocene‐aged sediment from Ocean Drilling Project (ODP) Site 1088 (Agulhas Ridge). Our measurements and mixing model calculations show that within‐population differences in carbon and oxygen isotopic ratios are largely independent of dissolution extent. By comparing population averages from coretop and downcore sediments, we find that lower oxygen isotopic ratios (likely driven by higher calcification temperatures) are associated with greater extents of dissolution at ODP Site 1088. We interpret this finding to reflect coupled changes in carbonate chemistry and climatic conditions over million‐year timescales.
Investigating Subsurface Properties of the Shallow Lunar Crust Using Seismic Interferometry on Synthetic and Recorded Data
Authors: Keil S. , Igel H. , Schimmel M. , Lindner F. , Bernauer F. 
Published: October 2024

AbstractIn the past few years, the remarkable progress of commercially operated spacecrafts, the success with reusable rocket engines, as well as the international competition to explore space, has led to a substantial acceleration of activities in the design and preparation of ambitious future lunar missions. In the search for ice and/or cavities imaging the shallow subsurface structure is of vital importance. Hereby, previous studies have shown that seismic interferometry is a promising method to investigate the subsurface properties from passive lunar data. In this study, we want to evaluate the potential of this method further by examining the required duration of seismic measurements and the influence of scattering on the Green's function retrieval. Therefore, we applied seismic interferometry to both measured Apollo 17 data and synthetic data. Our findings indicate that, under optimal conditions, a few hours of data are sufficient when using the method of time‐scaled phase‐weighted stack (ts‐PWS). However, this strongly depends on the inter‐station distance, the orientation toward the principal noise sources, and the timing of the measurement during the lunar cycle. Additionally, we were able to reproduce the measured data using numerical simulations in 2D. The synthetic results show that scattering effects clearly influence the Green's function extraction, especially for larger station distances.
An Ocean Memory Perspective: Disentangling Atmospheric Control of Decadal Variability in the North Atlantic Ocean
Authors: Khatri Hemant , Williams Richard G. , Woollings Tim , Smith Doug M. 
Published: October 2024

AbstractAn ocean memory framework is proposed to reveal the atmosphere's influence on ocean temperatures. Anomalous atmospheric forcing alters the ocean state through two mechanisms: short‐term, local effects involving airsea heat fluxes and Ekman circulation, and long‐term, far‐field effects involving changes from overturning and gyre circulations. The framework employs the Green function's method to incorporate both effects, enabling the quantification of ocean memory and the contribution of atmospheric forcing to ocean thermal variability. The framework is employed to examine the North Atlantic Oscillation's (NAO) influence on the North Atlantic Ocean variability, including the Atlantic Multidecadal Variability, with its memory estimated to be years. The NAO and variability in the North Atlantic jet speed explain up to 30% of ocean decadal variability, primarily driven by temporal changes in ocean heat transport. Therefore, decadal fluctuations in ocean temperatures cannot be accurately modeled solely as a passive response to stochastic atmospheric forcing.
Giant Kelvin‐Helmholtz (KH) Waves at the Boundary Layer of the Coronal Mass Ejections (CMEs) Responsible for the Largest Geomagnetic Storm in 20 Years
Authors: Nykyri Katariina 
Published: October 2024

AbstractStarting in the evening of 10 May 2024 the Earth's magnetosphere was hit by the coronal mass ejections (CMEs) creating the largest geomagnetic storm in 20 years. The CME encounter was characterized by variations of plasma number density and magnetic field. Here, I present the ARTEMIS observations at the lunar orbit during this event. The IMF ranged from −60 to +40 nT both with hour to minutes periodicity with plasma jets propagating in ‐direction within multi‐scale wave structures. Similar signature has been recently reported at the magnetopause by MMS spacecraft (Li et al., 2023, https://doi.org/10.1029/2023GL105539; Nykyri, 2024, https://doi.org/10.1029/2024GL108605) during a strongly southward IMF. Here, I show that the CME boundaries were KH unstable leading to multi‐scale density and magnetic field fluctuations including reconnection jets. The wavelengths varied from 60 to 270 , suggesting that the magnetosphere was periodically exposed to successive intervals of strongly northward and southward IMF leading to enhanced mass and magnetic flux loading.
Scaling Individual Tree Transpiration With Thermal Cameras Reveals Interspecies Differences to Drought Vulnerability
Authors: Javadian Mostafa , Aubrecht Donald M. , Fisher Joshua B. , Scott Russell L. , Burns Sean P. , Diehl Jen L. , Munger J. William , Richardson Andrew D. 
Published: October 2024

AbstractUnderstanding tree transpiration variability is vital for assessing ecosystem water‐use efficiency and forest health amid climate change, yet most landscape‐level measurements do not differentiate individual trees. Using canopy temperature data from thermal cameras, we estimated the transpiration rates of individual trees at Harvard Forest and Niwot Ridge. PT‐JPL model was used to derive latent heat flux from thermal images at the canopy‐level, showing strong agreement with tower measurements (R2 = 0.70–0.96 at Niwot, 0.59–0.78 at Harvard at half‐hourly to monthly scales) and daily RMSE of 33.5 W/m2 (Niwot) and 52.8 W/m2 (Harvard). Tree‐level analysis revealed species‐specific responses to drought, with lodgepole pine exhibiting greater tolerance than Engelmann spruce at Niwot and red oak showing heightened resistance than red maple at Harvard. These findings show how ecophysiological differences between species result in varying responses to drought and demonstrate that these responses can be characterized by deriving transpiration from crown temperature measurements.
The Evolution of Rock Size‐Frequency Distribution on the Moon: Effects of Rock Strength and Fragmentation Products on Centimeter‐Scale Abundances
Authors: Rüsch O. , Aussel B. 
Published: October 2024

AbstractRock abundances on the Moon represent both an opportunity to understand the history of the surface and of the regolith and a hazard to lander missions. While rock erasure by meteoroid bombardment is known to modify rock size˗frequency distributions, the interplay between rock erasure and rock exposure by impact cratering, and the resulting net rock abundance, is not known. Leveraging a coupling between modeling and optical imagery from the lunar orbit, we calculate new rock lifetimes that consider the specific shattering energy and the fragments produced by boulder shattering. We find differences between the estimated and expected specific shattering energy (Qs*), likely suggesting incomplete understanding of the scaling of the shattering energy with velocity and size. We find that the decrease in rock abundances with time on crater ejecta occurs faster than previous estimates based on thermal infrared data.
Evolution of Power‐Law Particle‐Size Distributions in Dense Grain‐Flow Experiments
Authors: Li Yan , Hu Wei , Xu Qiang , Huang Runqiu , Chang ChingShung , McSaveney Mauri 
Published: October 2024

AbstractUnderstanding particle fragmentation and its resulting particle‐size distribution is essential for comprehending shear zone formation, structure, and frictional behavior in faults and landslides, particularly at high normal stresses. 3‐D fractal dimension (D3) is used as a measure of particle‐size distribution, and for the potential self‐similarity physics. Previous research suggests D3 – 2.58 based on the “constrained comminution” model, or D3 = 3.00 considering large shear displacement. However, field data from rock avalanches reveal scattered D3 that deviate from these predictions, possibly due to the neglection of the underlying fragmented physics, such as the particle‐size‐dependent fragmentation probability. Herein, we conducted rotary shear experiments to investigate the evolution of D3 under varying normal stresses, velocities, and mineral compositions. Experimental results demonstrate that D3 monotonically increases with shear displacement and converges to an ultimate value, significantly influenced by mineral composition but less affected by shear velocity and confining stress within the experimental conditions. A modified large‐strain model that considered size‐dependent grain‐breakage probability was proposed, which may explain the observed divergence of D3 from previous predictions. This model highlights the complex mechanisms involved in particle breakage within dense grain‐flows, resulting in the high but scattered D3 observed in natural shear zones. Furthermore, we recognize that additional mechanisms, such as abrasion and grinding, can contribute to the particle size reduction and influence the ultimate fractal dimension. This study provides valuable insights into the dynamics of particle fragmentation in shear zones and has implications for understanding various geological processes.