bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graduelle Ditransitivität im Deutschen
Authors: Rauth Philipp 
Published: August 2016

Abstract
This paper is concerned with syntactic and semantic properties of ditransitive constructions in standard and dialectal German. A higher or lower extent of ‘ditransitivity’ can be observed by means of these properties. Canonical ditransitives, for instance, vary by allowing (geben ‘to give’) or prohibiting (gönnen ‘to grant’) a contextual ellipsis of the dative object. In addition, whether the proto-patient is either a concrete or an abstract noun can change the ditransitivity of the same construction. Non-canonical ditransitives (which contain e. g. complex predicates, certain APs or PPs that expand the valency of transitive verbs, a so-called ‘free dative’, or a ditransitive adjective) often remain unattended by studies on ditransitives. But none of these patterns differ from canonical geben with respect to their syntactic and semantic properties. Finally, only light verb constructions whose objects are categorically restricted represent the divide between (non-)canonical and idiomatic ditransitives.
Representation of Perceptual Color Space in Macaque Posterior Inferior Temporal Cortex (the V4 Complex)
Authors: Bohon Kaitlin S. , Hermann Katherine L. , Hansen Thorsten , Conway Bevil R. 
Published: August 2016

AbstractThe lateral geniculate nucleus is thought to represent color using two populations of cone-opponent neurons [L vs M; S vs (L + M)], which establish the cardinal directions in color space (reddish vs cyan; lavender vs lime). How is this representation transformed to bring about color perception? Prior work implicates populations of glob cells in posterior inferior temporal cortex (PIT; the V4 complex), but the correspondence between the neural representation of color in PIT/V4 complex and the organization of perceptual color space is unclear. We compared color-tuning data for populations of glob cells and interglob cells to predictions obtained using models that varied in the color-tuning narrowness of the cells, and the color preference distribution across the populations. Glob cells were best accounted for by simulated neurons that have nonlinear (narrow) tuning and, as a population, represent a color space designed to be perceptually uniform (CIELUV). Multidimensional scaling and representational similarity analyses showed that the color space representations in both glob and interglob populations were correlated with the organization of CIELUV space, but glob cells showed a stronger correlation. Hue could be classified invariant to luminance with high accuracy given glob responses and above-chance accuracy given interglob responses. Luminance could be read out invariant to changes in hue in both populations, but interglob cells tended to prefer stimuli having luminance contrast, regardless of hue, whereas glob cells typically retained hue tuning as luminance contrast was modulated. The combined luminance/hue sensitivity of glob cells is predicted for neurons that can distinguish two colors of the same hue at different luminance levels (orange/brown).
Commonalities in Development of Pure Breeds and Population Isolates Revealed in the Genome of the Sardinian Fonni's Dog
Authors: Dreger Dayna L , Davis Brian W , Cocco Raffaella , Sechi Sara , Di Cerbo Alessandro , Parker Heidi G , Polli Michele , Marelli Stefano P , Crepaldi Paola , Ostrander Elaine A 
Published: August 2016

AbstractThe island inhabitants of Sardinia have long been a focus for studies of complex human traits due to their unique ancestral background and population isolation reflecting geographic and cultural restriction. Population isolates share decreased genomic diversity, increased linkage disequilibrium, and increased inbreeding coefficients. In many regions, dogs and humans have been exposed to the same natural and artificial forces of environment, growth, and migration. Distinct dog breeds have arisen through human-driven selection of characteristics to meet an ideal standard of appearance and function. The Fonni’s Dog, an endemic dog population on Sardinia, has not been subjected to an intensive system of artificial selection, but rather has developed alongside the human population of Sardinia, influenced by geographic isolation and unregulated selection based on its environmental adaptation and aptitude for owner-desired behaviors. Through analysis of 28 dog breeds, represented with whole-genome sequences from 13 dogs and ∼170,000 genome-wide single nucleotide variants from 155 dogs, we have produced a genomic illustration of the Fonni’s Dog. Genomic patterns confirm within-breed similarity, while population and demographic analyses provide spatial identity of Fonni’s Dog to other Mediterranean breeds. Investigation of admixture and fixation indices reveals insights into the involvement of Fonni’s Dogs in breed development throughout the Mediterranean. We describe how characteristics of population isolates are reflected in dog breeds that have undergone artificial selection, and are mirrored in the Fonni’s Dog through traditional isolating factors that affect human populations. Lastly, we show that the genetic history of Fonni’s Dog parallels demographic events in local human populations.
Estilos parentais e desenvolvimento das funções executivas: estudo com crianças de 3 a 6 anos
Authors: Luxo Martins Gabriela Lamarca , Riccardi León Camila Barbosa , Seabra Alessandra Gotuzo 
Published: August 2016

Este estudo analisou a relação entre estilo parental dos responsáveis e funções executivas em pré-escolares, pois pesquisas prévias sugerem que características do ambiente familiar podem influenciar o desenvolvimento dessas funções. Participaram 30 crianças, de 3 a 6 anos, e seus responsáveis. Estes responderam o Inventário de Estilos Parentais e as crianças, Teste de Stroop Semântico, Teste de Atenção por Cancelamento e Teste de Trilhas para pré-escolares. Correlações de magnitude baixa a moderada evidenciaram, de modo geral, que quanto mais apropriado o estilo parental dos pais, melhor o controle de interferência dos filhos. Também observou-se que, quanto maior a inconsistência na punição, maior o tempo de reação da criança na parte incongruente do Teste de Stroop e mais ela é afetada pela incongruência, porém, conforme a parte B do Teste de Trilhas, maior a sua flexibilidade. Portanto observaram-se relações entre estilo parental e funções executivas na amostra avaliada.
Oral Health Literacy and Measures of Periodontal Disease
Authors: Holtzman Jennifer S. , Atchison Kathryn A. , Macek Mark D. , Markovic Daniela 
Published: August 2016

Background: Existing evidence demonstrating a relationship between health literacy (HL) and periodontal health is insufficient to identify how providers can help patients manage periodontal disease. This study assesses associations between HL measures (word recognition, numeracy, and conceptual knowledge) and signs of periodontal disease.Methods: This study included 325 new patients at a dental school clinic and employed an oral HL (OHL) survey, full‐mouth radiographs, and clinical examination. Evaluations included the relationship between each HL measure versus number of teeth, bleeding score, plaque score, and periodontal severity with linear and ordinal logistic regression models before and after adjusting for covariates.Results: Among HL measures, the Newest Vital Sign demonstrated a significant relationship with number of teeth and the Short Test of Functional Health Literacy in Adults showed a significant association with plaque score. The short Rapid Estimate of Adult Literacy in Medicine and Dentistry (REALMD‐20) showed participants who performed in the highest quartile had nearly two additional teeth, over 5.5% fewer bleeding sites, and nearly 9% fewer teeth with plaque after adjustment for demographic variables, smoking, and diabetes mellitus (DM). Participants who scored in the highest quartile of the Comprehensive Measure of Oral Health Knowledge (CMOHK) had nearly 9% less plaque.Conclusions: Two OHL instruments (REAMLD‐20 and CMOHK) provided statistical associations with clinical measures of periodontal health at a level that could be considered of moderate clinical relevancy. Findings suggest dentists may wish to assess familiarity of their patients with dental terminology and knowledge of periodontal disease to provide education on oral hygiene, smoking, and DM.
Oral Health and Mortality in Patients With Chronic Kidney Disease
Authors: Ruokonen Hellevi , Nylund Karita , Furuholm Jussi , Meurman Jukka H. , Sorsa Timo , Kotaniemi Karoliina , Ortiz Fernanda , Heikkinen Anna Maria 
Published: August 2016

Background: Factors related to mortality of patients with chronic kidney disease (CKD) were investigated to find out whether oral disease inflammatory burden or different etiology (diabetes nephropathy vs. other etiologies) of CKD could be associated with mortality.Methods: This prospective cohort study comprised 144 adults at the predialysis stage. Clinical oral and radiologic examination was made from 2000 to 2005. Patients were followed up until August 2015 (complete follow‐up time: 157 months). Cause of death could be verified from 62 of 65 patients. Clinical health data were combined with mortality records obtained from the Finland national statistics database. Number of teeth, total dental index (TDI), and periodontal inflammatory burden index were calculated to describe degree of oral inflammation.Results: Primary causes of death were cardiovascular diseases, infection, and cancer. There was a statistically significant difference in survival between diabetic nephropathy (23.8%) and other patients with CKD (59.9%; log‐rank test P <0.001). A Cox regression model showed fewer teeth, higher age, and diabetes mellitus were statistically significant independent risk factors for death. Deceased patients had fewer teeth (P <0.001) and higher TDI (P <0.05).Conclusions: Risk of death was higher among patients with diabetic nephropathy. The deceased had fewer teeth and more oral infections. However, indices used failed to show independent association with survival.
Periodontal Conditions of Sites Treated With Gingival Augmentation Surgery Compared With Untreated Contralateral Homologous Sites: An 18‐ to 35‐Year Long‐Term Study
Authors: Agudio Giancarlo , Cortellini Pierpaolo , Buti Jacopo , Pini Prato Giovanpaolo 
Published: August 2016

Background: The aim of this split‐mouth study is to compare long‐term (18 to 35 years) periodontal conditions of sites treated with gingival augmentation procedures (GAPs) and untreated homologous contralateral sites.Methods: Forty‐seven patients with 64 sites (test group), with lack of attached gingiva associated with recessions, were treated with marginal or submarginal free gingival grafts. Sixty‐four contralateral homologous sites (control group), with or without gingival recession (GR) and with attached gingiva, were left untreated. Patients were recalled every 4 to 6 months during follow‐up period. GR depth, keratinized tissue (KT) width, and probing depth were measured at baseline (T0), 1 year after surgery (T1), during follow‐up (10 to 27 years, T2), and at the end of the follow‐up period (18 to 35 years, T3). Multilevel and regression analyses were conducted.Results: At the end of T3, 83% of the 64 treated sites showed recession reduction (RecRed), whereas 48% of the 64 untreated sites experienced increase in recession. Treated sites ended with gingival margin (GM) 1.7 mm (P = 0.01) more coronal and KT 3.3 mm (P <0.001) wider than untreated sites. In grafted sites, KT at T3 remained stable compared with T1 value (4.1 mm, P <0.001).Conclusions: Sites treated with GAPs resulted in coronal displacement of GM with RecRed up to complete root coverage, whereas contralateral untreated sites showed a tendency to increase in existing recession or develop new recession during the 18‐ to 35‐year follow‐up.
Quality of Life and Poor Oral Health: A Comparison of Postmenopausal Women
Authors: Williams Kristin A. , Shamia Hebba , DeBaz Christine , Palomo Leena 
Published: August 2016

Interrelationships between traditional dental variables are becoming more evident in far reaching aspects of life such as psychosocial interaction, self-esteem, overall health and even occupational performance. This study compares quality of life (QoL) in postmenopausal women (PMW) with poor oral health (POH) with QoL in PMW with good oral health.
200 randomly recruited PMW received a dental evaluation and completed Utian Quality of Life Survey. The participants were divided into POH and healthy groups based on dental exam. Mean scores were calculated for each QoL item, domain and the overall summary score. For each of the four parameters for periodontitis diagnosis, periodontitis patients’ QoL outcomes were compared to those of healthy patients using T-test with threshold of significance at p
Sustentabilidade na Organização Contemporânea Brasileira: uma análise literária sob o planejamento estratégico
Authors: Bartolomeo Ricardo Di , Da Silva Emerson Pereira , Fonseca Cesar Da Costa 
Published: August 2016

O presente artigo propõe uma abordagem nas organizações sob os aspectos relacionados à visão, atitude e ações corretamente sustentáveis como fatores de diferenciação e competitividade de mercado, além de se fazer cumprir as responsabilidades legais. Para atingir a proposta de estudo, revisou-se a literatura sobre sustentabilidade e sua influência no aumento de clientes e parceiros comerciais. Os resultados demosntraram que a elaboração adequada de um planejamento estratégico é fundamental para que as organizações possam ser reconhecidas como sustentáveis.
Topicality of the Second Vatican Council Constitution Dei Verbum in Contemporary Biblical Studies
Authors: Zbroja Bogdan 
Published: August 2016

Artykuł traktuje o zakorzenieniu konstytucji o Bożym Objawieniu Soboru Watykańskiego II we współczesnym naukowym i eklezjologicznym podejściu do Pisma Świętego. Biblia bowiem wyrasta z wiary Kościoła i tę wiarę, wraz z Tradycją, buduje. Całość opracowana jest w trzech punktach. Najpierw uwaga skupia się na Bogu, który objawia człowiekowi samego siebie i swą wolę zbawienia ludzkości. Następnie jest mowa o sposobach komunikowania się Boga z człowiekiem przy pomocy autorów ludzkich oraz długi proces tworzenia dzieł natchnionych kanonu ksiąg świętych. Jest wreszcie podkreślona konieczność odpowiedzi człowieka na Boże Słowo, dzięki czemu istota ludzka wchodzi w dialog zbawczy ze swoim Ojcem, przez Jego Syna w Duchu Świętym. Wspólnota wiary Kościoła stanowi naturalne środowisko badań, lektury i życia Słowem Bożym, do czego zachęca w swoim zakończeniu Konstytucja Dei Verbum (nr 25).
A functional account of grammatical number in English reflexive pronouns
Authors: Stern Nancy 
Published: August 2016

Number morphology appears twice in English reflexive pronouns, first on the pronominal-possessive portion of the form, and second on the inflectional ending. Usually, the two number markings co-vary, but ‘crossed’ number forms like ourself and themself – and even myselves and herselves – are also attested. This paper argues that the two opportunities to signal number can be creatively exploited for communicative purposes, and are not controlled syntactically. The data and analysis presented provide support for a view of grammatical categories (even those commonly regarded as syntactically determined) as independent bearers of meaning.
IL-12 Signals through the TCR To Support CD8 Innate Immune Responses
Authors: Goplen Nicholas P. , Saxena Vikas , Knudson Karin M. , Schrum Adam G. , Gil Diana , Daniels Mark A. , Zamoyska Rose , Teixeiro Emma 
Published: August 2016

Abstract
CD8 T cells must integrate antigenic and inflammatory signals to differentiate into efficient effector and memory T cells able to protect us from infections. The mechanisms by which TCR signaling and proinflammatory cytokine receptor signaling cooperate in these processes are poorly defined. In this study, we show that IL-12 and other proinflammatory cytokines transduce signals through the TCR signalosome in a manner that requires Fyn activity and self-peptide–MHC (self-pMHC) interactions. This mechanism is crucial for CD8 innate T cell functions. Loss of Fyn activity or blockade of self-pMHC interactions severely impaired CD8 T cell IFN-γ and NKG2D expression, proliferation, and cytotoxicity upon cytokine-mediated bystander activation. Most importantly, in the absence of self-pMHC interactions, CD8 memory T cells fail to undergo bystander activation upon an unrelated infection. Thus, CD8 T cell bystander activation, although independent of cognate Ag, still requires self-pMHC and TCR signaling.
Complement Destabilizes Cardiomyocyte Function In Vivo after Polymicrobial Sepsis and In Vitro
Authors: Kalbitz Miriam , Fattahi Fatemeh , Herron Todd J. , Grailer Jamison J. , Jajou Lawrence , Lu Hope , Huber-Lang Markus , Zetoune Firas S. , Sarma J. Vidya , Day Sharlene M. , Russell Mark W. , Jalife José , Ward Peter A. 
Published: August 2016

Abstract
There is accumulating evidence during sepsis that cardiomyocyte (CM) homeostasis is compromised, resulting in cardiac dysfunction. An important role for complement in these outcomes is now demonstrated. Addition of C5a to electrically paced CMs caused prolonged elevations of intracellular Ca2+ concentrations during diastole, together with the appearance of spontaneous Ca2+ transients. In polymicrobial sepsis in mice, we found that three key homeostasis-regulating proteins in CMs were reduced: Na+/K+-ATPase, which is vital for effective action potentials in CMs, and two intracellular Ca2+ concentration regulatory proteins, that is, sarcoplasmic/endoplasmic reticulum calcium ATPase 2 and the Na+/Ca2+ exchanger. Sepsis caused reduced mRNA levels and reductions in protein concentrations in CMs for all three proteins. The absence of either C5a receptor mitigated sepsis-induced reductions in the three regulatory proteins. Absence of either C5a receptor (C5aR1 or C5aR2) diminished development of defective systolic and diastolic echocardiographic/Doppler parameters developing in the heart (cardiac output, left ventricular stroke volume, isovolumic relaxation, E′ septal annulus, E/E′ septal annulus, left ventricular diastolic volume). We also found in CMs from septic mice the presence of defective current densities for Ik1, l-type calcium channel, and Na+/Ca2+ exchanger. These defects were accentuated in the copresence of C5a. These data suggest complement-related mechanisms responsible for development of cardiac dysfunction during sepsis.
Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism
Authors: Iwata Terri N. , Ramírez Julita A. , Tsang Mark , Park Heon , Margineantu Daciana H. , Hockenbery David M. , Iritani Brian M. 
Published: August 2016

Abstract
Mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that coordinates nutrient and growth factor availability with cellular growth, division, and differentiation. Studies examining the roles of mTOR signaling in immune function revealed critical roles for mTOR in regulating T cell differentiation and function. However, few studies have investigated the roles of mTOR in early B cell development. In this study, we found that mTOR is highly activated during the pro- and pre-B stages of mouse B cell development. Conditional disruption of the mTOR coactivating protein Raptor in developing mouse B cells resulted in a developmental block at the pre-B cell stage, with a corresponding lack of peripheral B cells and loss of Ag-specific Ab production. Pre-B cell survival and proliferation were significantly reduced in Raptor-deficient mice. Forced expression of a transgenic BCR or a BclxL transgene on Raptor-deficient B cells failed to rescue B cell development, suggesting that pre-BCR signaling and B cell survival are impaired in a BclxL-independent manner. Raptor-deficient pre-B cells exhibited significant decreases in oxidative phosphorylation and glycolysis, indicating that loss of mTOR signaling in B cells significantly impairs cellular metabolic capacity. Treatment of mice with rapamycin, an allosteric inhibitor of mTOR, recapitulated the early B cell developmental block. Collectively, our data reveal a previously uncharacterized role for mTOR signaling in early B cell development, survival, and metabolism.
Detection Thresholds of Archaeological Features in Airborne Lidar Data from Central Yucatán
Authors: Magnoni Aline , Stanton Travis W. , Barth Nicolas , Fernandez-Diaz Juan Carlos , León José Francisco Osorio , Ruíz Francisco Pérez , Wheeler Jessica A. 
Published: August 2016

AbstractIn this article we evaluate ∼48km2of airborne lidar data collected at a target density of 15 laser shots/m in central Yucatán, Mexico. This area covers parts of the sites of Chichén Itzá and Yaxuná, a kilometer-wide transect between these two sites, and a transect along the first few kilometers of Sacbé 1 from Yaxuná to Cobá. The results of our ground validation and mapping demonstrate that not all sizable archaeological features can be detected in the lidar images due to: (1) the slightly rolling topography interspersed with 1-6 m-high bedrock hummocks, which morphologically mimic house mounds, further complicated by the presence of low foundations; (2) the complex forest structure in central Yucatán, which has particularly dense near-ground understory resulting in a high number of mixed-signal ground and low vegetation returns which reduces the fidelity and accuracy of the bare-earth digital elevation models; and (3) the predominance of low archaeological features difficult to discern from the textural noise of the near-ground vegetation. In this article we explore different visualization techniques to increase the identification of cultural features, but we conclude that, in this portion of the Maya region, lidar should be used as a complement to traditional on-the-ground survey techniques.
Mapping Ritual Landscapes Using Lidar
Authors: Moyes Holley , Montgomery Shane 
Published: August 2016

AbstractData collected from aerial lidar scanning provides new opportunities for archaeological survey. It is now possible, in a short period of time, to collect vast amounts of geographic data that would have taken years of pedestrian survey to acquire. This enhances and extends landscape studies by reducing time-frames and cost, encouraging analyses based on real-world data collection on a regional scale. This paper describes an approach for modeling the ritual landscape surrounding the ancient Maya center of Las Cuevas, Belize by analyzing the spatial aspects of ritual cave use. Using lidar-derived data, we describe a method for locating potential cave sites using Local Relief Models, which requires only a working knowledge of relief visualization techniques and no specialized skills in computer programming. Our method located the five known cave sites within our 222 km2lidar study area—including one with a fissure entrance. We plan to ground-truth potentialities to develop models of the ritual landscape that can be visualized and analyzed. By researching cave use on a regional scale and defining the relationships between caves and surface features, we advance cave studies by deepening our understanding of the ritual landscape and its articulation with ancient Maya socio/political dynamics.