bluuebunny/crossref_metadata_2025_split huggingface dataset:
Entropy generation outcomes in peristalsis of Carreau–Yasuda nanofluid flow with activation energy
Authors: Zahir Hina , Muhammad Khursheed , Nisar Zahid , Alnfiai Mrim M. , Elseesy Ibrahim E. 
Published: October 2024

AbstractThis paper focuses on the study of activation energy and entropy generation in the peristaltic flow of a Carreau–Yasuda nanofluid. Peristaltic transport, coupled with entropy generation and activation energy in a curved geometry, has significant applications in biomedical and industrial processes involving non‐Newtonian fluids. Blood flow in the arteries, the movement of chyme in the gastrointestinal tract, and peristaltic motion replicate the natural muscular contractions that drive fluid flow in the physiological systems. The integration of entropy generation allows for the evaluation of energy efficiency and the analysis of losses due to viscous dissipation. Activation energy plays a crucial role in processes such as drug delivery, where temperature‐sensitive reactions or biochemical changes affect fluid behavior. In industrial applications, like peristaltic pumps in chemical reactors or polymer processing, the consideration of entropy and activation energy aids in optimizing thermal management and reaction rates. The mathematical model is developed under these assumptions, and the governing equations are numerically solved using the NDSolve function in Mathematica. Graphical results show that higher activation energy and concentration reduce the reaction rate, while the Bejan number and entropy generation increase with a larger Brinkman number. Velocity and temperature increase under slip conditions, whereas concentration decreases, and a stronger radial magnetic field reduces both velocity and the size of the trapped bolus.
Analysis of the three‐dimensional elasticity theory problem for a radially inhomogeneous cylinder
Authors: Akhmedov Natiq K. 
Published: October 2024

AbstractIn this paper an axisymmetric problem of elasticity theory for a radially inhomogeneous cylinder of small thickness is studied. It is assumed that homogeneous mixed boundary conditions are specified on lateral surfaces of the cylinder, and boundary conditions that leave the cylinder in equilibrium are specified on the ends of the cylinder. It is considered that elastic moduli are arbitrary continuous functions of a variable along the radius of the cylinder. The formulated boundary value problem is reduced to a spectral problem containing a small parameter characterizing the thinness of the cylinder walls. To determine its solution, the method of asymptotic integration is used, based on three iteration processes. All solutions of the equilibrium equation are constructed, satisfying the specified homogeneous boundary conditions on lateral surfaces. It is obtained that the solution of the problem consists of a penetrating solution and a solution of the nature of the boundary layer. An analysis of stress‐strain states corresponding to different types of solutions is carried out. Based on the constructed asymptotic solutions, a connection is found between the solutions obtained by the equation of elasticity theory and by the applied theory of shells. It is shown that the penetrating solution determines the internal stress‐strain state of a radially inhomogeneous cylinder. The stress state determined by the penetrating solution is equivalent to the principal vector of stress acting in a cross section perpendicular to the axis of the cylinder.The first terms of asymptotic expansions of the penetrating solution in a small parameter coincide with solutions in the applied theory of shells. New classes of solutions are defined as the character of a boundary layer, which are localized at the ends of the cylinder and decrease exponentially with distance from the ends. These solutions are absent in the applied theories of shells. The first terms of the asymptotic expansion of the solution, having the nature of a boundary layer, are equivalent to the Saint‐Venant edge effect in the theory of heterogeneous plates. Asymptotic formulas for displacement and stresses are constructed, allowing one to calculate the three‐dimensional stress‐strain state of a radially heterogeneous cylinder of small thickness with any predetermined accuracy. Based on the obtained asymptotic expansions, one can estimate the applicability areas of applied theories and construct a refined applied theory for radially heterogeneous cylindrical shells.
Environmental Humanities in India: An Interdisciplinary Approach
Authors: Biswas Debajyoti 
Published: October 2024

AbstractThe Environmental Humanities, or EH, is a multifaceted, relatively new, and swiftly evolving field of scholarship that integrates the theories and approaches of various disciplines—from anthropology, art, communications, cultural studies, philosophy and ecology to history, literature, media, music, performance, politics, sociology, theology and theatre. Practitioners of this markedly integrative field aim to address and, even, confront today’s urgent ecological and cultural challenges, namely climate change, urban sustainability, biodiversity conservation, species decline, energy policy, the exigencies of the Anthropocene, environmental activism and Indigenous peoples’ justice. Recent developments in the Environmental Humanities foreground its topicality as scholar-activists-artists from a wide range of disciplines turn increasingly to human-nature relational issues in the Anthropocene epoch. As a discrete field, EH has emerged principally from North American, European and Australian academic institutions and, more specifically, from English, history, geography and anthropology departments. Although the Environmental Humanities has been relatively slow to gain traction in South Asia, the overall momentum towards transdisciplinary approaches to ecology and sustainability is intensifying in India. This contributed volume highlights current research in the Environmental Humanities in India through four thematic sections: (i) Indigenous Perspectives: Conservation, Spirituality and Language; (ii) Theoretical Grounding: Education, Law and Ethics; (iii) Literary Formulations: Memoir, Parable and Storyworlds; (iv) Popular Narratives: Myth, Travel and Music.
Mourning the Loss of Mother Earth: Examining Human-Water Interrelationships in Akkineni Kutumbarao’s Softly Dies a Lake
Authors: Sarkar Somasree 
Published: October 2024

AbstractIn today’s industrialized world, the degradation of the environment is a major concern, recognized to have severe impacts on the planet and its inhabitants. The current environmental changes are attributed to anthropogenic activities, making human beings the discernible factors behind the current climate crisis. Human perceptions related to exceptionalism and exemptionalism are at the core of hubris, triggering the proclivity to exploit the more-than-human world. The unrelenting exploitative measures of human beings toward nonhuman entities have injured and damaged the Earth irrevocably, jeopardizing the planet’s biodiversity and ecological balance. The Earth is often conceptualized as ‘Mother Earth’ for its sustaining abilities and nurturing qualities. The concept of ‘Mother Earth’ encompasses the interrelated lives of human and nonhuman beings and the Indigenous traditions that eulogize human-nonhuman interrelations (Shiva, 2020). The present corporate culture is disrupting the interrelationship between humans and nonhumans, widening the chasm between the two, thereby, disturbing the balance of Mother Earth. This can be viewed as a deprivation of Mother Earth’s rights since her well-being is dependent on the stable relationship between all the species she sustains and nurtures (Shiva, 2020). In connection with the preceding discussion, the present chapter seeks to critically analyze the novel, Softly Dies a Lake originally written in Telugu by Akkineni Kutumbarao (2014), and later translated by Vasanth Kannabiran into English (2020). The author through his eco-memoir records the slow dying of the largest freshwater lake in India, Kolleru, located in the state of Andhra Pradesh owing to the mercenary practices of humans. Kutumbarao characterizes the lake as the living figure of a mother who nurtures multiple species in the region. The dying of the lake signifies the loss of the mother who sustains the balance in the ecosystem. The chapter, therefore, endeavours to show how the exploitive measures deprive Mother Earth, here identified with Kolleru, of her well-being and rights. Also, it attempts to show how the dying of Lake Kolleru degrades the livelihood of those people thriving on her, triggering mourning for the ecological loss. Finally, the chapter will interrogate the possibility of recovery from eco-mourning by striking a balance between the human and nonhuman world in the region surrounding Lake Kolleru.
The Anthropocene in South Asian Popular Music: A Critical Examination of Papon’s “Waise Hi Rehna, Waise Hi Behna” Through an Ecomusicological Lens
Authors: Sharma Manvi , Chaubey Ajay K. , Singh Surendra 
Published: October 2024

AbstractThrough storylines dealing with catastrophic changes, visual media has much been celebrated and appreciated for its efforts to evoke the perils of the Anthropocene in South Asia. But as the crises escalate, other cultural artefacts, especially popular songs, are being explored and harnessed by musicians, bands, and singers across the region to promote environmental awareness. Over the past decade, as popular music culture has mushroomed in the Indian Sub-continent, its extraordinary potential to grasp the attention of consumers towards environmental concerns is being utilized by renowned Indian musicians. These artists have yoked the potential of popular music to reflect issues of environment and sustainability. Exploring the trajectory and topoi of ecomusicology and drawing theoretical insights from it, this chapter examines singer and music composer Papon’s song ‘Waise hi Rehna, Waise hi Behna’—a plea for river conservation. The work brings together music and environment to address the anthropogenic environmental crisis that has gripped the Indian sub-continent. Through a detailed examination of individual sections of the song, the chapter emphasizes that the pollution of rivers in India, that Papon alludes to, fits well into Rob Nixon’s understanding of “slow violence” and Dipesh Chakravarty’s perceptions of the “planetary crisis.” The chapter further scrutinizes the elements—ecologically-charged lyrics and cinematography—that the song employs to provoke public awareness of the human-induced ecological catastrophe. The chapter also explores the various aspects of listening to songs and music within the framework of ecology and environment, strengthening the argument that eco-songs illustrate music as a reliable medium to promote environmental sustainability.
Indigenous Native Epistemology as a Model in Environmental Humanities in India
Authors: Beggiora Stefano 
Published: October 2024

AbstractThe article proposes a reflection on the contribution of the ādivāsī issue in the broader debate on Environmental Humanities in India. The theme of indigeneity on the one hand and the ontological turn in anthropology on the other have highlighted the centrality and importance of the ecological message in the theoretical approach of these disciplines. However, the paper investigates a possible originality of Indian thought in a debate that too often, even in postcolonial studies, has been manipulated by the West. Through the case study of some indigenous cultures of central-eastern India, the paper proposes some original examples of indigenous ontologies and shamanism conveying an idea of respect and consubstantiality of man with other non-humans and with an earth that is mother for everyone. The essay concludes by mentioning the pioneering vision of two of the first Indian anthropologists who understood the importance of the man-spirits-nature connection and of a holistic vision of the cosmos among the native cultures of the Subcontinent.
The Environment in Hindu Consciousness: Revisiting the Sacred Texts
Authors: Sharma Susheel Kumar , Biswas Debajyoti 
Published: October 2024

AbstractTo understand the Hindu consciousness of the environment, one will have to understand the essence of Hinduness. While Hindu is a term derived from Sindhu, a term of reference by the invaders for the people living on the banks of the Sindhu River, the people preferred calling themselves Sanatani, which implies an eternal and all-encompassing form of life. It will not be too far-fetched to refer to the practices of the Hindus as syncretic and ever-evolving because of the plurality of practices, symbiotic relationships, and tolerance towards human and non-human forms of life. There is no binary opposition between the self and the other in Sanatani life because all forms of life emanate from the same source and go back to the same. Furthermore, human life itself is constituted of the five elements (Pancha Bhuta): Prithvi (earth), Jal (water), Agni (fire), Vayu (air), and Akasha (Space). While Nature is constituted of these five elements, the human body is also constituted of the same. The implication is that what is external is also internal and because of this there is no binary of the self and the other. Since such faith is embedded in the practice and function of the life system in India, the question of any external consciousness does not arise. In other words, human and non-human forms of life are integral to nature. Sanatani understanding of nature is a clear mark of departure from Western thought where nature is to be dominated and exploited (see Francis Bacon's Novum Organum). In this chapter we undertake to explain this relation and explore the way scriptural and traditional practices among the Hindus could offer a sustainable future for mankind in the Anthropocene epoch.
Cultural Practices and Indigenous Traditions of the Garo and Bodo: Reinterpreting ‘Man-Nature’ Convergences in Wangala and Bathou
Authors: Pathak Namrata , Brahma Rustam 
Published: October 2024

AbstractThe chapter, by deviating from the current debates on the morbid and disastrous turn in Anthropocenic discourses, aims to create an ‘alternative space’ that invests in the porousness of ‘man-nature’ borders, the constant negotiations and exchanges between them by looking at Indigenous cultural forms of the Garo and Bodo as a meeting point of both agential power and ‘naturalness’ of ecospheres. By reading the different stages of the Wangala festival of the Garo and Bathou of the Bodo, this chapter analyzes how such cultural practices are embodied performances of a community rooted in the region’s landscapes displaying a localized human-nature alignment that counters Western anthropocentricism. The discussion also considers how these cultural practices are connected to human production systems and in the process become a means to archive cultural conservation, patterns of shifting cultivation, and an Indigenous community’s movement through various sociopolitical pathways. Moreover, the chapter places Wangala at the heart of agricultural activities related to tended landscapes such as clearing, planting, ritual activities, pruning, weeding, harvesting, and resource pooling, thus highlighting a symbiotic human-nature conjunction. Bathou is located in the Bodo Indigenous landscape that relies on the organic growth of the cosmic whole, a conceptual framework that takes into its fold an ecocentric worldview countering Western cultural practices.
Multispecies Conviviality, Bioregionalism, and Vegetal Politics in Kodagu, India
Authors: De Subarna 
Published: October 2024

AbstractThe essay examines the changing human-plant geographies in Kodagu, situated in the Western Ghats in southern India. Paying attention to Kodagu helps investigate how “plantiness” impacts resource politics in Indigenous landscapes across pre-colonial, colonial, and post-colonial timeframes. This chapter will study Sarita Mandanna’s Tiger Hills (2010) and Kavery Nambisan’s The Scent of Pepper (2010) from a bioregional perspective to understand the importance of native plants, forests, vegetal, and feral spaces across Kodagu’s shifting societies and timeframes and investigate how the human-plant encounters redefine the role of plants in Kodagu’s more-than-human geographies. With a particular focus on the Kodava ritual of Kailpodh, this chapter will explore how humans often classify plants as native, invasive, weeds, sacred, and unwanted, depending on their impact on human social life and how ritualizing plants such as rajakirita helps to reinhabit Kodagu and deepens the Kodava human-plant interaction across space and time.
Dissociation Characteristics Simulation of Ammonia, a Propellant for Solar Thermal Propulsion
Authors: Huang Minchao , Wu Jianjun , Li Jian , Cheng Yuqiang 
Published: October 2024

AbstractThe ideal working temperature of a solar thermal propulsion (STP) system is generally above 2200 K, and at this temperature, ammonia (NH3) can dissociate; therefore, it is not accurate to use a single ammonia propellant for the calculation and analysis of thruster performance, and the components of the mixture after ammonia dissociation should be considered. The mixture after ammonia dissociation is composed of atoms and molecules. Since the temperature usually does not exceed 3000 K (it is difficult for high-temperature resistant materials to achieve this temperature), the existence of ionic components can be completely ignored. For vibrational excitation, only molecular nitrogen and hydrogen are considered, which have stable vibrational excitation levels. This chapter focuses on the effect of chemical reactions on the propellant temperature and thruster performance. In an actual 3D flow field, the dissociation characteristics and temperature variation of the ammonia propellant mixture are completely different from those of lumped parameters. The 3D flow field distribution and component distribution pattern are obtained through numerical simulation. This chapter mainly discusses the flow and composition change pattern of the ammonia propellant mixture inside of the heat exchanger core and the nozzle.
Methamphetamine-induced cardiotoxicity: in search of protective transcriptional mechanisms
Authors: Annawald Kristin , Streckfuss-Bömeke Katrin , Meyer Thomas 
Published: October 2024

AbstractCrystalline methamphetamine hydrochloride is an illegal drug with a high addictive potential, better known by its colloquial name “ice” or “crystal meth”. The abuse of this drug has led to significant health problems worldwide. Like other amphetamine-type stimulants, chronic consumption of methamphetamine leads to direct toxic effects on the central nervous system, causing cognitive impairment, depressive behavior, and other severe neurological or psychiatric symptoms. Besides its neurotoxicity, the drug exhibits numerous deleterious effects on the cardiovascular system, including hypertension, accelerated atherosclerosis, vasospasm-induced acute coronary syndromes, sudden cardiac death, and dilated cardiomyopathy with congestive heart failure and left ventricular dysfunction. The excessive release of catecholamines upon methamphetamine exposure causes vasoconstriction and vasospasm, which ultimately lead to hypertension, tachycardia, endothelial dysfunction, and cardiotoxicity. While numerous studies have focused on transcription factors expressed in the brain that cause the neurotoxic effects of the drug, much less is known about transcription factors involved in the development of methamphetamine-induced heart failure. In this article, we provide an overview of the Janus kinase–signal transducer and activator of transcription 3 (JAK–STAT3) pathway involved in ischemia/reperfusion injury in the myocardium, which may be activated by the vasospasm-inducing action of the drug. However, much more work is needed to decipher the precise role of STAT protein family members, including the potentially cardioprotective STAT3, in the pathogenesis of methamphetamine-induced cardiotoxicity.
Exploring cutting-edge approaches in diabetes care: from nanotechnology to personalized therapeutics
Authors: Asaad Gihan F. , Doghish Ahmed S. , Rashad Ahmed A. , El-Dakroury Walaa A. 
Published: October 2024

AbstractDiabetes mellitus (DM) is a persistent condition characterized by high levels of glucose in the blood due to irregularities in the secretion of insulin, its action, or both. The disease was believed to be incurable until insulin was extracted, refined, and produced for sale. In DM, insulin delivery devices and insulin analogs have improved glycemic management even further. Sulfonylureas, biguanides, alpha-glucosidase inhibitors, and thiazolidinediones are examples of newer-generation medications having high efficacy in decreasing hyperglycemia as a result of scientific and technological advancements. Incretin mimetics, dual glucose-dependent insulinotropic polypeptide, GLP-1 agonists, PPARs, dipeptidyl peptidase-4 inhibitors, anti-CD3 mAbs, glucokinase activators, and glimins as targets have all performed well in recent clinical studies. Considerable focus was placed on free FA receptor 1 agonist, protein tyrosine phosphatase-1B inhibitors, and Sparc-related modular calcium-binding protein 1 which are still being studied. Theranostics, stem cell therapy, gene therapy, siRNA, and nanotechnology are some of the new therapeutic techniques. Traditional Chinese medicinal plants will also be discussed. This study seeks to present a comprehensive analysis of the latest research advancements, the emerging trends in medication therapy, and the utilization of delivery systems in treating DM. The objective is to provide valuable insights into the application of different pharmaceuticals in the field of diabetes mellitus treatment. Also, the therapeutic approach for diabetic patients infected with COVID-19 will be highlighted. Recent clinical and experimental studies evidence the Egyptian experience. Finally, as per the knowledge of the state of the art, our conclusion and future perspective will be declared.
Azacitidine in combination with shortened venetoclax treatment cycles in patients with acute myeloid leukemia
Authors: Fleischmann Maximilian , Jentzsch Madlen , Brioli Annamaria , Eisele Florian , Frietsch Jochen J. , Eigendorff Farina , Tober Romy , Schrenk Karin G. , Hammersen Jakob Friedrich , Yomade Olaposi , Hilgendorf Inken , Hochhaus Andreas , Scholl Sebastian , Schnetzke Ulf 
Published: October 2024

AbstractThe combination of venetoclax with hypomethylating agents is currently the standard of care for elderly patients with acute myeloid leukemia (AML) ineligible for intensive chemotherapy. Despite its favorable efficacy, clinical use is often associated with post-remission cytopenia, frequently necessitating treatment delays and dose modifications. This study aims to evaluate the efficacy and safety of shortened venetoclax treatment durations. A multicenter analysis was conducted involving 20 adult AML patients receiving venetoclax (7 or 14 days with 9 and 11 patients, respectively) combined with 5-azacitidine (5–7 days) between 2021 and 2024. The cohort included patients from four German academic centers all treated in first line. Outcome measures included bone marrow response, transfusion dependence, overall survival (OS) and progression-free survival (PFS). Median age was 73.5 years, with 70% of patients having secondary AML. Adverse molecular risk was observed in 75% of patients. The overall response rate (ORR) was 100%, with a composite complete remission rate of 78%. No significant differences in response rates were observed between the 7-day and 14-day venetoclax regimens. Median OS for the cohort was 15 months. Infection-related complications were observed in 55% of patients, with severe sepsis in 20% of cases. In this cohort, shortened venetoclax regimens demonstrated efficacy comparable to standard treatment protocols, with a potential reduction in hematologic toxicity. These findings support the individualization of treatment regimens to optimize clinical outcomes while potentially minimizing adverse effects.