bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrasonic monitoring to assess the impacts of forest conversion on Solomon Island bats
Authors: Davies Tammy E. , Ruzicka Filip , Lavery Tyrone , Walters Charlotte L. , Pettorelli Nathalie 
Published: June 2016

AbstractPaleotropical islands are experiencing extensive land‐use change, yet little is known about how such changes are impacting wildlife in these biodiversity hotspots. To address this knowledge gap, we characterized bat responses to forest conversion in a biodiverse, human‐threatened coastal rainforest habitat on Makira, Solomon Islands. We analysed ~200 h of acoustic recordings from echolocating bats in the four dominant types of land use on Makira: intact forest, secondary forest, food gardens and cacao plantations. Bat calls were identified to the species level using a supervised classification model (where labelled data are used to train the system). We examined relative activity levels and morphological traits across habitats. Relative activity levels were highest in intermediately disturbed habitats and lowest in the most heavily disturbed habitat, although these differences were not significant. There were significant differences in the mean forearm length of bat assemblages across habitats, with the highest mean forearm length found in the most open habitat (Cacao). Overall, our study constitutes the first detailed exploration of anthropogenic effects on mammalian diversity in the Solomon Islands and includes the first acoustic and morphological information for many bat species in Melanesia. We use our experience to discuss the challenges of acoustic monitoring in such a remote and poorly studied region.
Hyaluronan Upregulates Mitochondrial Biogenesis and Reduces Adenoside Triphosphate Production for Efficient Mitochondrial Function in Slow-Proliferating Human Mesenchymal Stem Cells
Authors: Solis Mairim Alexandra , Wei Yau-Huei , Chang Chiung-Hsin , Yu Chen-Hsiang , Kuo Pao-Lin , Huang Lynn L.H. 
Published: June 2016

Abstract
Hyaluronan-coated surfaces preserve the proliferation and differentiation potential of mesenchymal stem cells by prolonging their G1-phase transit, which maintains cells in a slow-proliferative mode. Mitochondria are known to play a crucial role in stem cell self-renewal and differentiation. In this study, for the first time, the metabolic mechanism underlying the hyaluronan-regulated slow-proliferative maintenance of stem cells was investigated by evaluating mitochondrial functions. Human placenta-derived mesenchymal stem cells (PDMSCs) cultured on hyaluronan-coated surfaces at 0.5, 3.0, 5.0, and 30 µg/cm2 were found to have an average 58% higher mitochondrial mass and an increase in mitochondrial DNA copy number compared to noncoated tissue culture surfaces (control), as well as a threefold increase in the gene expression of the mitochondrial biogenesis-related gene PGC-1α. Increase in mitochondrial biogenesis led to a hyaluronan dose-dependent increase in mitochondrial membrane potential, ATP content, and oxygen consumption rate, with reactive oxygen species levels shown to be at least three times lower compared to the control. Although hyaluronan seemed to favor mitochondrial function, cell entry into a hyaluronan-regulated slow-proliferative mode led to a fivefold reduction in ATP production and coupling efficiency levels. Together, these results suggest that hyaluronan-coated surfaces influence the metabolic proliferative state of stem cells by upregulating mitochondrial biogenesis and function with controlled ATP production. This more efficiently meets the energy requirements of slow-proliferating PDMSCs. A clear understanding of the metabolic mechanism induced by hyaluronan in stem cells will allow future applications that may overcome the current limitations faced in stem cell culture.
Practical formulas towards distortional buckling failure analysis for steel–concrete composite beams
Authors: Zhou Wang‐Bao , Li Shu‐Jin , Yan Wang‐Ji 
Published: June 2016

SummaryAs the most predominant type of failure for steel–concrete composite beams (SCCBs) in negative moment area, distortional buckling is significantly impacted by the interaction effect between the applied loading and the torsional–lateral restraint stiffness of the bottom flange, which is termed as loading–restraint interaction here for short. Recently, a modified elastic foundation beam method capable of considering the interaction effect properly was proposed to calculate critical buckling moment for SCCBs under negative uniform moment. As a sequel to such development, a functional relationship between two dimensionless auxiliary parameters (i.e. equivalent slenderness ratio and equivalent moment coefficient) is discovered in this study. On the basis of the close association between the pair of dimensionless parameters, empirical formulas are derived in a remarkably simply explicit form to evaluate the critical buckling moment for SCCBs under negative uniform moment or moment gradient. These formulas are simple, user‐friendly and of practical use. Compared with conventional approaches without considering the loading–restraint interaction effect, the practical approach developed in this paper can achieve higher accuracy and is more easy‐implemented. The study lays a foundation for determining the ultimate bearing capacity of SCCBs considering moment gradient effect rapidly. Copyright © 2016 John Wiley & Sons, Ltd.
The Value of Abdominal Drainage After Laparoscopic Cholecystectomy for Mild or Moderate Acute Calculous Cholecystitis: A Post Hoc Analysis of a Randomized Clinical Trial
Authors: Prevot Flavien , Fuks David , Cosse Cyril , Pautrat Karine , Msika Simon , Mathonnet Muriel , Khalil Haitham , Mauvais François ,   the FRENCH Cholecystitis Working Group, Arnaud J. P. , Arvieux C. , Bonnetain F. , Chiche L. , Collet D. , Haccart V. , Lacaine F. , Millat B. , Paquet J. C. , Sielezneff I. , Slim K. , Vons C. , Regimbeau Jean‐Marc 
Published: June 2016

AbstractBackgroundAlthough the preoperative management of mild and moderate (Grade I–II) acute calculous cholecystitis (ACC) has been standardized, there is no consensus on the value of abdominal drainage after early cholecystectomy.MethodsIn a post hoc analysis of a randomized controlled trial (NCT01015417) focused on the value of postoperative antibiotic therapy in patients with ACC, we determined the value of abdominal drainage in patients having undergone laparoscopic cholecystectomy for Grades I–II ACC. All postoperative complications were analyzed after using a propensity score. A post hoc test was used to assess the statistical robustness of our results.ResultsOf the 414 enrolled patients, 178 did not have abdominal drainage (forming the no‐drainage group) and 236 had drainage (the drainage group). After matching on PS, the deep incisional site infection was 1.1 versus 0.8 %, p = 0.78. This result is similar for the superficial incisional site infections; the distant infections; the overall morbidity, and the readmission rate. Only the hospital length of stay was significantly longer in the drainage group (3.3 vs. 5.1 days, p = 0.003). Neither abdominal drainage nor the absence of postoperative antibiotic therapy was found to be a risk factor for deep incisional site infections.ConclusionsThe use of abdominal drainage depends on the surgeon’s personal preferences but is often used in high‐risk populations. However, abdominal drainage does not appear to be of any benefit (in terms of postoperative outcomes) and may even compromise recovery in patients having undergone early laparoscopic cholecystectomy for mild or moderate ACC.
Impaired Gastrointestinal Function Affects Symptoms and Alimentary Status in Patients After Gastrectomy
Authors: Konishi Hideo , Nakada Koji , Kawamura Masahiko , Iwasaki Taizo , Murakami Keishiro , Mitsumori Norio , Yanaga Katsuhiko 
Published: June 2016

AbstractBackgroundPostgastrectomy syndrome (PGS) remains a common complication after gastrectomy that affects patients’ quality of life. Although impaired gastrointestinal (GI) function by gastrectomy procedures is thought to be the cause, the precise pathophysiology of PGS is yet to be clarified.AimThe aim of this study was to investigate relationships between GI function and various symptoms or alimentary status in patients after gastrectomy.MethodsFifty‐one patients who underwent total or distal gastrectomy at least 1 year previously were studied. All patients replied to a questionnaire that asked presence of symptoms (esophageal reflux, nausea, abdominal pain, early satiation, diarrhea, early dumping general, early dumping abdominal, and late dumping symptoms) and alimentary status (change in body weight, food intake per meal, frequency of meals per day). They also underwent assessment of GI function consisting of gastric emptying study by 13C‐acetate breath test to examine reservoir capacity and gastric emptying, and water load drink test to evaluate tolerance to volume loading (TVL). The relationships between GI function and each symptom or alimentary status were examined.ResultsThe patients with nausea and early dumping general symptoms had significantly smaller reservoir capacity*, the patients with diarrhea and early dumping general symptoms had significantly faster gastric emptying*, and the patients with early satiation and early dumping abdominal symptoms had significantly impaired TVL*. Significant correlations were identified between TVL and body weight changes* or food intake per meal* (* p < 0.05).ConclusionImpaired postoperative GI function was closely related to symptoms or worse alimentary status.
Ospemifene May Not Treat Vulvar Atrophy: A Report of Two Cases
Authors: Goldstein Andrew T. , King Michelle A. 
Published: June 2016

Abstract

Introduction
Ospemifene (Osphena, Shionogi Inc, Florham, NJ, USA) is an estrogen agonist and antagonist approved by the U.S. Federal Drug Administration for the treatment of “moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause.” Although published, peer-reviewed, placebo-controlled studies have shown objective improvement in dyspareunia and in vaginal atrophy, there are no published data that have assessed changes in vulvar atrophy after the use of ospemifene.

Aim
To present two cases of women with severe vulvar atrophy that showed no improvement with the use of ospemifene.

Methods
A review of two recent cases of a clinic specializing in the treatment of vulvovaginal disorders was performed. Case 1 was a 53-year-old menopausal woman who presented with non-provoked vulvar and vaginal discomfort and introital dyspareunia. She had used ospemifene 60 mg/d for 1.5 years without improvement in her symptoms before presentation. Case 2 was a 57-year-old menopausal woman who also presented with non-provoked vulvar rawness, burning, irritation, vaginal dryness, and introital dyspareunia. She had started ospemifene 60 mg/d 1 year before presentation and reported mild improvement in her vaginal dryness but no improvement in her vulvar irritation or introital dyspareunia.

Main Outcome Measures
Change in vulvar atrophy and introital dyspareunia.

Conclusion
These cases highlight the need to perform additional clinical trials that specifically assess the efficacy of ospemifene for changes in vulvar atrophy.
Wrapping up a century of splashes
Authors: van der Meer Devaraj 
Published: June 2016

Few fluid phenomena are as beautiful, fragile and ephemeral as the crown splash that is created by the impact of an object on a liquid. The crown-shaped phenomenon and the physics behind it have mesmerised and intrigued scientists for over a century, and still the scientific world has not yet uncovered all of the secrets of the splash. This is exemplified in a particularly striking manner in Marston et al. (J. Fluid Mech., vol. 794, 2016, pp. 506–529) where a 6 m tall vacuum chamber is employed to study the splash formed upon impact of a sphere onto a deep liquid pool, at both atmospheric and reduced ambient pressures. They shed light into the classical problem of the surface seal and study the buckling of the splash. With an almost magical touch they devise a method to create a splash without the liquid and the sphere ever coming into contact. The images that accompany the paper – taken with state-of-the-art high-speed cameras – are as stunning as the physics that is uncovered in them.
Dynamics of hemiwicking
Authors: Kim Jungchul , Moon Myoung-Woon , Kim Ho-Young 
Published: June 2016

Hemiwicking refers to the spreading of a liquid on a rough hydrophilic surface driven by capillarity. Here, we construct scaling laws to predict the velocity of hemiwicking on a rough substrate and experimentally corroborate them with various arrangements and dimensions of micropillar arrays. At the macroscopic scale, where the wetting front appears parallel to the free surface of the reservoir, the wicking distance is shown to grow diffusively, i.e. like $t^{1/2}$ with $t$ being time. We show that our model is consistent with pillar arrays of a wide range of pitch-to-height ratios, either square or skewed. At the microscopic scale, where the meniscus extension from individual pillars at the wetting front is considered, the extension distance begins to grow like $t$ but the spreading slows down to behave like $t^{1/3}$ when the meniscus is far from the pillar. Our microscopic flow modelling allows us to find pillar spacing conditions under which the assumption of densely spaced pillars is valid.
Tidal bending and strand cracks at the Kamb Ice Stream grounding line, West Antarctica
Authors: HULBE CHRISTINA L. , KLINGER MARIN , MASTERSON MEGAN , CATANIA GINNY , CRUIKSHANK KENNETH , BUGNI ANDREA 
Published: June 2016

ABSTRACTAn extensive set of shore-parallel fractures are observed at the grounding line of Kamb Ice Stream (KIS) in West Antarctica. Seismicity measured in the grounding zone is, as elsewhere around Antarctica, tidally forced and moreover strand cracks propagate nearly exclusively on the falling tide. Measured surface deflection and a model of fracture propagation are used to conclude that bending on the falling tide favors propagation while bending on the rising tide suppresses propagation. Without the perturbation due to tidal bending, strand cracks would be rare and appear farther downstream than observed. We speculate that the very large number of cracks observed at KIS is due to the stagnant-to-floating transition at that grounding line, which allows cyclic bending of the same ice and relatively large stretching rates.
THE HANF NUMBER FOR AMALGAMATION OF COLORING CLASSES
Authors: KOLESNIKOV ALEXEI , LAMBIE-HANSON CHRIS 
Published: June 2016

AbstractWe study amalgamation properties in a family of abstract elementary classes that we call coloring classes. The family includes the examples previously studied in [3]. We establish that the amalgamation property is equivalent to the disjoint amalgamation property in all coloring classes; find the Hanf number for the amalgamation property for coloring classes; and improve the results of [3] by showing, in ZFC, that the (disjoint) amalgamation property for classes Kα studied in that paper must hold up to ℶα (only a consistency result was previously known).
SEPARABLY CLOSED VALUED FIELDS: QUANTIFIER ELIMINATION
Authors: HONG JIZHAN 
Published: June 2016

AbstractIt is proved in this article that the theory of separably closed nontrivially valued fields of characteristic p > 0 and imperfection degree e > 0 (e ≤ ∞) has quantifier elimination in the language ${{\cal L}_{p,{\rm{div}}}} = \{ + , - , \times ,0,1\} \cup {\{ {\lambda _{n,j}}(x;{y_1}, \ldots ,{y_n})\} _{0 \le n < \omega ,0 \le j < {p^n}}} \cup \{ |\}$; in particular, when e is finite, the corresponding theory has quantifier elimination in the language ${\cal L} = \{ + , - , \times ,0,1\} \cup \{ {b_1}, \ldots ,{b_e}\} \cup {\{ {\lambda _{e,j}}(x;{b_1}, \ldots ,{b_e})\} _{0 \le j < {p^e}}} \cup \{ |\}$.
Increased 14C AMS Efficiency from Reduced Competitive Ionization
Authors: Vogel John S , Giacomo Jason A 
Published: June 2016

AbstractObservation of 80 µA/mm2 C– current from a 0.5-mm-diameter sample compared to 20 µA/mm2 from a 1-mm-diameter sample contradicts the long-held surface ionization hypothesis of cesium sputter ion source operation. Resonant ionization occurs in neutral Cs plasma above a sample in a sputtered pit or well. A collision-radiation model of that plasma followed electronic excitation and radiation relaxation up to the Cs(7d) state. The Cs(5d) metastable state dominates plasma in a 1-mm-diameter well, but high electron densities in narrow wells drive a majority to Cs(7d) and higher. Competitive ionization by Al2 dimers from the sample holder reduces Cs(7s,p) states resonant in ionization energy with C–. Al anions from states above Cs(7p) in narrow wells also diminish radiation cascades to the Cs(7s,p), reducing C–. We tested sample wells of non-ionizing Zn to maintain high ionization efficiency for small samples in narrow wells.
Presidential address: Experimenting with the scientific past
Authors: RADICK GREGORY 
Published: June 2016

AbstractWhen it comes to knowledge about the scientific pasts that might have been – the so-called ‘counterfactual’ history of science – historians can either debate its possibility or get on with the job. Taking the latter course means re-engaging with some of the most general questions about science. It can also lead to fresh insights into why particular episodes unfolded as they did and not otherwise. Drawing on recent research into the controversy over Mendelism in the early twentieth century, this address reports and reflects on a novel teaching experiment conducted in order to find out what biology and its students might be like now had the controversy gone differently. The results suggest a number of new options: for the collection of evidence about the counterfactual scientific past, for the development of collaborations between historians of science and science educators, for the cultivation of more productive relationships between scientists and their forebears, and for heightened self-awareness about the curiously counterfactual business of being historical.
Status, genetic diversity and gaps in sorghum germplasm from South Asia conserved at ICRISAT genebank
Authors: Upadhyaya H. D. , Reddy K. N. , Vetriventhan M. , Krishna Gumma Murali , Irshad Ahmed M. , Thimma Reddy M. , Singh Shailesh Kumar 
Published: June 2016

AbstractThe genebank at ICRISAT, India that serves as a world repository for sorghum germplasm conserves 39,234 accessions from 93 countries, including 6249 from seven South Asian countries: Afghanistan (6), Bangladesh (9), India (6101), the Maldives (10), Nepal (8), Pakistan (90) and Sri Lanka (25). A total of 5340 georeferenced accessions were used to identify gaps, and 5322 accessions that were characterized at ICRISAT were used to assess the diversity in the collection. Accessions of basic races varied widely than those of intermediate races for flowering in the postrainy season, plant height in both rainy and postrainy seasons, panicle exsertion, panicle length and width, seed size and 100 seed weight. Landraces from India were late flowering, tall and produced stout panicles and larger seeds. Landraces from Pakistan flowered early in both seasons and produced stout panicles and those from Sri Lanka were late flowering and tall in both seasons, produced more basal tillers and stout panicles. A total of 110 districts in 20 provinces of India, 13 districts in three provinces of Pakistan, three districts in Bangladesh and five districts in four provinces of Sri Lanka were identified as geographical gaps. Sorghum bicolor subsp. verticilliflorum, S. halepense and S. propinquum were identified as taxonomic gaps in the collection. Therefore, it is suggested to explore the districts identified as gaps to enrich the variability in the world collection of sorghum at ICRISAT.
From Anglo-Saxon Nativism to Executive Order: Civil Religion and Anti-Immigration Rhetoric
Authors: O'Leary Ryan T. 
Published: June 2016

AbstractThis article examines one aspect of current disagreements over immigration reform — Anglo-Saxon nativist rhetoric — through the lens of civil religion. It argues that the idea of America as a “New Jerusalem” can sometimes take on a nativist and even ethno-centric cast. The analysis uses two case studies to articulate the ways in which this nativism can play out in terms of civil religion: Patrick J. Buchanan's folding of immigration concerns into his culture wars rhetoric and some of the far-right rhetoric coming out of the 2016 presidential race in America. This sort of rhetoric can also be found surrounding President Obama's executive action on immigration. The analysis shows that these fears combine a view of American “chosenness” with a sense of existential threat generated by rapid demographic changes. However, while this rhetoric is grounded in civil religion, it is also a symptom of the corruption of the prophetic core of American civil religion.
UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly
Authors: Hunziker Mirjam , Barandun Jonas , Petfalski Elisabeth , Tan Dongyan , Delan-Forino Clémentine , Molloy Kelly R. , Kim Kelly H. , Dunn-Davies Hywel , Shi Yi , Chaker-Margot Malik , Chait Brian T. , Walz Thomas , Tollervey David , Klinge Sebastian 
Published: June 2016

AbstractEarly eukaryotic ribosome biogenesis involves large multi-protein complexes, which co-transcriptionally associate with pre-ribosomal RNA to form the small subunit processome. The precise mechanisms by which two of the largest multi-protein complexes—UtpA and UtpB—interact with nascent pre-ribosomal RNA are poorly understood. Here, we combined biochemical and structural biology approaches with ensembles of RNA–protein cross-linking data to elucidate the essential functions of both complexes. We show that UtpA contains a large composite RNA-binding site and captures the 5′ end of pre-ribosomal RNA. UtpB forms an extended structure that binds early pre-ribosomal intermediates in close proximity to architectural sites such as an RNA duplex formed by the 5′ ETS and U3 snoRNA as well as the 3′ boundary of the 18S rRNA. Both complexes therefore act as vital RNA chaperones to initiate eukaryotic ribosome assembly.
MLP and CARP are linked to chronic PKCα signalling in dilated cardiomyopathy
Authors: Lange Stephan , Gehmlich Katja , Lun Alexander S. , Blondelle Jordan , Hooper Charlotte , Dalton Nancy D. , Alvarez Erika A. , Zhang Xiaoyu , Bang Marie-Louise , Abassi Yama A. , dos Remedios Cristobal G. , Peterson Kirk L. , Chen Ju , Ehler Elisabeth 
Published: June 2016

AbstractMLP (muscle LIM protein)-deficient mice count among the first mouse models for dilated cardiomyopathy (DCM), yet the exact role of MLP in cardiac signalling processes is still enigmatic. Elevated PKCα signalling activity is known to be an important contributor to heart failure. Here we show that MLP directly inhibits the activity of PKCα. In end-stage DCM, PKCα is concentrated at the intercalated disc of cardiomyocytes, where it is sequestered by the adaptor protein CARP in a multiprotein complex together with PLCβ1. In mice deficient for both MLP and CARP the chronic PKCα signalling chain at the intercalated disc is broken and they remain healthy. Our results suggest that the main role of MLP in heart lies in the direct inhibition of PKCα and that chronic uninhibited PKCα activity at the intercalated disc in the absence of functional MLP leads to heart failure.