bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring service users’ experience of community meetings in a high secure service
Authors: Mayes Danielle , Ramsden Sarah Victoria , Braham Louise , Whitaker Zoe , Norburn Mark 
Published: September 2016

Purpose
The purpose of this paper is to explore service users’ experience of community meetings (CMs) within a high secure setting.

Design/methodology/approach
A qualitative design was employed in which focus groups were used to capture service users’ experience of CMs. In all, 12 focus groups comprising a total of 27 participants were carried out using a semi-structured interview schedule. Data were analysed using thematic and saliency analysis, identifying themes which were pertinent to the research aims.

Findings
Positive experiences reported by service users included a safe space to explore ward issues and develop skills, with some viewing the meeting as a therapeutic forum in which to facilitate personal growth.

Research limitations/implications
There were a wide range of patient presentations and views. Furthermore, only 20 per cent of the patient population were included within this study.

Practical implications
A number of recommendations have been identified that can have positive implications for patients (quality of life and recovery), staff (resolving conflicts and problem-solving) and the overall therapeutic milieu of the ward.

Originality/value
There are no reviews looking at CMs within the last decade. This paper brings the understanding up to date to allow the development of this potentially positive tool.
Social networks and mental health: an egocentric perspective
Authors: Levula Andrew , Harré Michael 
Published: September 2016

PurposeThe purpose of this paper is to examine the relationship between egocentric social networks and mental health (MH) outcomes. The authors aim to develop a theoretical framework for understanding this association and to test whether social network factors add any further explanatory power to MH outcomes.Design/methodology/approachData for this study were drawn from the Household, Income and Labour Dynamics in Australia survey (n=14,756). The authors used hierarchical multiple regression technique to test this hypothesis and using the Akaike information criterion (AIC) the authors identified the best fit model.FindingsThe results of this study shows that social network measures do add considerable explanatory power to MH with social isolation (SI) having the highest influence (β=−0.198,p<0.001) followed by social connections (SCs) (β=0.141, p<0.001) and then social trust (ST) (β=0.071, p<0.001). The AIC best fit model included all the social network predictors however it excluded physical functioning which contributed very little.Originality/valueThis study shows that social network factors play a significant role in predicting MH outcomes. In particular, SI was a more significant predictor of MH than SC. However, ST played a relatively minor role in predicting MH scores. These findings have practical implications and applications for the design of policy initiatives aimed at improving MH outcomes.
Equivalent or not?
Authors: Lim Choon Boey , Bentley Duncan , Henderson Fiona , Pan Shin Yin , Balakrishnan Vimala Devi , M. Balasingam Dharshini , Teh Ya Yee 
Published: September 2016

Purpose
The purpose of this paper is to examine issues academics at importing institutions face while delivering Australian degrees in Malaysia. Transnational higher education (TNE) has been widely researched. However, less widely researched is the area of understanding what academics at the offshore locations need to uphold the required academic standards of their partnered exporting universities. This area warrants close attention if Australian and other transnational education universities are to sustain their growth through a partnership model with offshore academics delivering a portion (often a substantial portion) of the teaching.

Design/methodology/approach
Two focus groups were conducted with a mix of long standing and newly recruited Malaysian lecturers who taught into an Australian degree through a partnership arrangement. The semi-structured questions which were used were derived from a preliminary literature review and previous internal institutional reports.

Findings
The findings from the focus groups indicate that TNE is largely “Australian-centric” when addressing the standard of academic quality and integrity. The findings pointed not so much to any sustained internationalisation of curriculum or administration or personnel but more as internationalisation as deemed required by the local academic.

Originality/value
To a greater extent, the findings highlighted that equivalent student outcomes do not necessarily equate to equivalent learning experiences or teaching workload. In fact, the frustration of the interviewees on the tension to fulfil the home institution curriculum and helping students to “comprehend” an Australian-centric curriculum translates to “additional and unrecognised workload” for the interviewees.
Targeted harassment, subcultural identity and the embrace of difference: a case study
Authors: Hodkinson Paul , Garland Jon 
Published: September 2016

AbstractThis paper examines the significance of experiences and understandings of targeted harassment to the identities of youth subcultural participants, through case study research on goths. It does so against a context of considerable recent public discussion about the victimization of alternative subcultures and a surprising scarcity of academic research on the subject. The analysis presented indicates that, although individual direct experiences are diverse, the spectre of harassment can form an ever‐present accompaniment to subcultural life, even for those who have never been seriously targeted. As such, it forms part of what it is to be a subcultural participant and comprises significant common ground with other members. Drawing upon classic and more recent understandings of how subcultural groups respond to broader forms of outside hostility, we show how the shared experience of feeling targeted for harassment tied in with a broader subcultural discourse of being stigmatized by a perceived ‘normal’ society. The role of harassment as part of this, we argue, contributed to the strength with which subcultural identities were felt and to a positive embrace of otherness.
Recovery of fertility in quinestrol‐treated or diethylstilbestrol‐treated mice: Implications for rodent management
Authors: LIU Ming , LUO Rongcan , WANG Hao , CAO Guangming , WANG Yanling 
Published: September 2016

AbstractFertility control is an alternative strategy to traditional culling for the management of rodent pests. Previous studies have demonstrated that quinestrol is a potential contraceptive for male rodents, but the recovery of fertility in quinestrol‐treated rodents has not been evaluated. This study used C57BL/6J mice to evaluate the recovery rate of male fertility after the administration of quinestrol. Diethylstilbestrol (DES), a non‐steroid estrogenic compound, was used for comparison. Different groups of mice were treated with 1 mg/kg quinestrol, 1 mg/kg DES, or castor oil separately for 7 days. These mice were then killed on days 8, 22 and 50 respectively. Our results indicated that the weight of epididymides and seminal vesicles decreased significantly on days 8 and 22 in quinestrol/DES‐treated mice, with extensive histological changes in the seminiferous tubules. Sperm concentrations in the cauda epididymal fluid were significantly reduced on days 8 and 22 in both quinestrol and DES treatment groups and on day 50 for the DES, but not the quinestrol group. Further analysis revealed that DES‐treated mice exhibited a higher proportion of abnormal sperm accumulation in the epididymis, indicating that the normal sperm transportation to the cauda epididymis was blocked. Our results indicate that the anti‐fertility effects on male mice given quinestrol were of shorter duration than for those receiving DES at the dose of 1 mg/kg body weight.
Identification of the sex‐determining region in flathead grey mullet (Mugil cephalus)
Authors: Dor L. , Shirak A. , Rosenfeld H. , Ashkenazi I. M. , Band M. R. , Korol A. , Ronin Y. , Seroussi E. , Weller J. I. , Ron M. 
Published: September 2016

SummaryElucidation of the sex‐determination mechanism in flathead grey mullet (Mugil cephalus) is required to exploit its economic potential by production of genetically determined monosex populations and application of hormonal treatment to parents rather than to the marketed progeny. Our objective was to construct a first‐generation linkage map of the M. cephalus in order to identify the sex‐determining region and sex‐determination system. Deep‐sequencing data of a single male was assembled and aligned to the genome of Nile tilapia (Oreochromis niloticus). A total 245 M. cephalus microsatellite markers were designed, spanning the syntenic tilapia genome assembly at intervals of 10 Mb. In the mapping family of full‐sib progeny, 156 segregating markers were used to construct a first‐generation linkage map of 24 linkage groups (LGs), corresponding to the number of chromosomes. The linkage map spanned approximately 1200 cM with an average inter‐marker distance of 10.6 cM. Markers segregating on LG9 in two independent mapping families showed nearly complete concordance with gender (R2 = 0.95). The sex determining locus was fine mapped within an interval of 8.6 cM on LG9. The sex of offspring was determined only by the alleles transmitted from the father, thus indicating an XY sex‐determination system.
Neuroprotective Effects of Sulphated Agaran from Marine Alga Gracilaria cornea in Rat 6‐Hydroxydopamine Parkinson's Disease Model: Behavioural, Neurochemical and Transcriptional Alterations
Authors: Souza Ricardo Basto , Frota Annyta Fernandes , Sousa Rayane Siqueira , Cezario Nayara Araújo , Santos Tarcizio Brito , Souza Luziana Mara Frota , Coura Chistiane Oliveira , Monteiro Valdécio Silvano , Cristino Filho Gerardo , Vasconcelos Silvânia Maria Mendes , da Cunha Rodrigo Maranguape Silva , Aguiar Lissiana Magna Vasconcelos , Benevides Norma Maria Barros 
Published: September 2016

AbstractParkinson's disease (PD) is a multifactorial disease associated with the degeneration of dopaminergic neurons and behavioural alterations. Natural bioactive compounds may provide new therapeutic alternatives for neurodegenerative disorders, such as PD. The sulphated polysaccharides isolated from marine algae are heterogenic molecules that show different biological activities. The red marine alga Gracilaria cornea has a sulphated polysaccharide (SA‐Gc) with structure and anti‐inflammatory and antinociceptive activities reported in the literature. Therefore, this study aimed to evaluate the neuroprotective effects of SA‐Gc in rat model PD induced by 6‐hydroxydopamine (6‐OHDA). Firstly, we established the PD model in rats, induced by an intrastriatal injection (int.) of 6‐OHDA, followed by a single administration of SA‐Gc (15, 30 or 60 μg; int.). On the 14th day, behavioural tests were performed. After killing, brain areas were dissected and used for neurochemical and/or transcriptional analyses. The results showed that SA‐Gc (60 μg, int.) promoted neuroprotective effects in vivo through reducing the oxidative/nitroactive stress and through alterations in the monoamine contents induced by 6‐OHDA. Furthermore, SA‐Gc modulated the transcription of neuroprotective and inflammatory genes, as well as returning behavioural activities and weight gain to normal conditions. Thus, this study reports the neuroprotective effects of SA‐Gc against 6‐OHDA in rats.
Addiction, Heroin‐Assisted Treatment and the Idea of Abstinence: A reply to Henden
Authors: Uusitalo Susanne , Broers Barbara 
Published: September 2016

AbstractIn our previous article on the question whether heroin addicts are able to give informed consent voluntarily to research on heroin‐assisted treatment, we criticized the ongoing bioethical discussion of a flawed conceptualization of heroin addicts' options. As a participant in this discussion, Edmund Henden defends the conceptualization as sufficient for determining whether heroin addicts are able to give informed consent to the research on heroin‐assisted treatment voluntarily. This discussion on research on heroin‐assisted treatment seems to go astray in several respects. In his reply to our article Henden maintains some of the biases, such as the necessity of abstinence in recovery, that seem to prevail in addiction research on a more general level as well. These biases run the danger of having implausible ethical implications on stakeholders in addiction research and treatment. In our reply to him, we will further clarify and discuss the importance of describing the relevant issues in plausible terms that do justice to the realities of the cases of informed consent in research on heroin‐assisted treatment and also raise a wider issue of the ethics of wording as well as of the narrow scope, or ‘tunnel vision’, in addiction research as currently conducted.
“Post‐thrombotic panic syndrome”: A thematic analysis of the experience of venous thromboembolism
Authors: Hunter Rachael , Lewis Sarah , Noble Simon , Rance Jaynie , Bennett Paul D. 
Published: September 2016

ObjectivesVenous thromboembolism (VTE, including deep vein thrombosis [DVT] and pulmonary embolism [PE]) is a serious, potentially traumatic, life‐threatening condition and a major cause of mortality and morbidity. The aim of this study was to explore the patients’ experiences ofVTEand its psychosocial impact.MethodsAudio‐recorded semistructured interviews with a purposive sample of 12 participants who had experienced a first‐timeDVTorPEwithin the previous 6 months. Interviews were transcribed and thematically analysed.ResultsFour key themes with 10 subthemes were identified. The major themes were as follows:VTEas life‐changing and traumatic, living with uncertainty and fear of reoccurrence, feeling let down by health services, and positive changes and outcomes. The content of themes varied according to age at the time ofVTEand participants’ experiences of diagnosis and treatment.ConclusionsThe data demonstrate the psychosocial impact ofVTEas life‐changing, encompassing a dynamic duality of trauma and growth. The findings highlight a potential role for health care professionals in identifying and supporting individuals at risk of post‐traumatic stress, and targeted interventions to enhance psychological well‐being and recovery and reduce distress.Statement of contributionWhat is already known on this subject?Venous thromboembolism (VTE) is often characterized by sudden onset and may carry a significant threat to life, particularly in the form of pulmonary embolism.Early studies suggest that health‐related quality of life is negatively affected byVTEand there is likely to be a high prevalence of trauma.What does this study add?This study explores for the first time the experience of, and reactions to,VTEin the 6 months following its occurrence.It explores the role that psychological well‐being can play in recovery afterVTE.This study highlights that improvements are needed to supportVTEpatients to cope with the emotional impact ofVTE.A dual process of trauma and post‐traumatic growth afterVTEis reported for the first time.
Diagnostic accuracy of computed tomography urography and visual assessment during ureterorenoscopy in upper tract urothelial carcinoma
Authors: Grahn Alexandra , Melle‐Hannah Miden , Malm Camilla , Jäderling Fredrik , Radecka Eva , Beckman Mats , Brehmer Marianne 
Published: September 2016

ObjectiveTo investigate diagnostic accuracy of multiphase computed tomography urography (MCTU) and visual assessment at ureterorenoscopy (URS) for detection of upper tract urothelial carcinoma (UTUC).Patients and MethodsConsecutive patients referred to our tertiary care centre were included in a prospective study covering the period 2005 to 2012. The patients underwent initial imaging and URS with focal samples taken. Cytopathological results served as reference standard.ResultsWe investigated 174 renal units (RUs; renal pelvis and adjacent ureter) in 148 patients. UTUC was found in 104 RUs. MCTU had an accuracy of 0.74, sensitivity of 0.89, specificity of 0.51, positive predictive value of 0.73, and negative predictive value of 0.75; corresponding values for URS were 0.84, 0.84, 0.85, 0.89, and 0.78, respectively. MCTU had significantly higher sensitivity and accuracy compared with other imaging techniques (P<0.05). Compared with MCTU, URS had similar sensitivity but significantly greater specificity and accuracy.ConclusionBoth MCTU and URS are important tools in the diagnostic evaluation of UTUC although neither of those techniques achieves 100% accuracy. MCTU should be chosen as the radiographical method if there are no contraindications and URS should always be combined with focal cytology and biopsies of suspicious lesions. To enhance diagnostic precision both MCTU and URS with focal samples should be included in the diagnostic procedure. The present results add impact to current diagnostic guidelines.
Pathological analysis of the prostatic anterior fat pad at radical prostatectomy: insights from a prospective series
Authors: Ball Mark W. , Harris Kelly T. , Schwen Zeyad R. , Mullins Jeffrey K. , Han Misop , Walsh Patrick C. , Partin Alan W. , Epstein Jonathan I. 
Published: September 2016

ObjectiveTo assess factors associated with lymphatic drainage and lymph node (LN) metastasis to the prostatic anterior fat pad (PAFP) in men with prostate cancer and the utility of routine PAFP analysis at the time of radical prostatectomy (RP).Patients and MethodsOur institution began to prospectively collect PAFP tissue in 2010. The PAFP was removed at the time of RP and sent as a pathological specimen separate from the pelvic LNs and prostate. Consecutive RPs performed at our institution in which the PAFP was removed were reviewed to determine the rate of LNs in the PAFP, the rate of metastatic LNs in the PAFP, and the association of metastatic PAFP LN with clinical and pathological features. The impact on biochemical recurrence (BCR) was assessed with a Cox's proportional hazard model.ResultsIn all, 2 413 PAFP specimens were available for analysis. LNs were found in the PAFP in 255 (10.6%) cases and metastatic LNs in the PAFPs were found in 14 (0.6%) cases. Metastatic PAFP LNs were associated with anterior tumours in 11 of the 14 cases (P = 0.01), and were present only in preoperative D'Amico intermediate‐ (six of 14) and high‐ (eight of 14) risk patients (P < 0.001). Metastatic PAFP LNs were associated with extraprostatic disease in 13 of the 14 cases, although concomitant pelvic LN involvement was present in only four of the 14 cases. With a mean follow‐up of 1.5 years, three of the 14 patients with metastatic PAFP LN developed BCR. Positive LN involvement in either the pelvic LN or PAFP had worse BCR than LN‐negative patients (P < 0.001); however, there was no difference in BCR between patients with positive pelvic LN and positive PAFP LN (P = 0.5).ConclusionMetastatic PAFP LNs are rare and always occur in the presence of other adverse pathological features. The routine pathological analysis of PAFP as a separate specimen, especially in low‐risk disease, may not be warranted.
Incorporation and Remodeling of Bone Block Allografts in the Maxillary Reconstruction: A Randomized Clinical Trial
Authors: Deluiz Daniel , Santos Oliveira Luciano , Ramôa Pires Fábio , Reiner Teresita , Armada Luciana , Nunes Marcus A. , Muniz Barretto Tinoco Eduardo 
Published: September 2016

AbstractBackgroundSevere alveolar atrophy often presents a challenge for the implant surgery. The significant lack of bone in the alveolar ridges may compromise the final restorations both from the aesthetic and functional standpoints.ObjectivesTo evaluate the behavior of bone block allografts for the maxillary augmentation and to investigate its incorporation, remodeling, and implant survival rates in two different healing time points.Material and MethodsSixty‐six consecutive patients (52 female/14 male, mean age: 57.95 ± 9.06 years old), presenting 113 atrophic alveolar ridges underwent maxillary augmentation with fresh‐frozen allogeneic bone blocks from tibia. Patients were randomly assigned in two groups: Group 1—patients who would wait 4 months for implant placement after grafting, and Group 2—patients who would wait 6 months. Events of infection, suture dehiscence or mucosal perforation were recorded. Cone‐beam computed tomography scans were compared volumetrically between the time of the grafting surgery and reentry procedure after incorporation. Biopsies were collected and subjected to histological, histomorphometric and immunehistochemical analysis.ResultsA total of 305 implants were placed in the reconstructed sites. The mean resorption rate in Group 1 (13.98% ± 5.59) was significantly lower than Group 2 (31.52% ± 6.31). The amount of calcified tissue, newly formed bone and remaining graft particles demonstrated no difference between groups. The samples showed evident immunolabeling for the podoplanin protein in both groups. The implants cumulative survival rate was 94.76%.ConclusionsThe findings of the present study indicate that there is a significant difference regarding the resorption of the grafts when waiting 4 or 6 months before placing the implants, even though no difference was found in the histological, histomorphometric, and immunohistochemical features. Both 4‐month and 6‐months healing times are suitable for the implant placement.
An unrestricted diet for uncomplicated diverticulitis is safe: results of a prospective diverticulitis diet study
Authors: Stam M. A. W. , Draaisma W. A. , van de Wall B. J. M. , Bolkenstein H. E. , Consten E. C. J. , Broeders I. A. M. J. 
Published: September 2016

AbstractAimThe optimal diet for uncomplicated diverticulitis is unclear. Guidelines refrain from recommendation due to lack of objective information. The aim of the study was to determine whether an unrestricted diet during a first acute episode of uncomplicated diverticulitis is safe.MethodA prospective cohort study was performed of patients diagnosed with diverticulitis for the first time between 2012 and 2014. Requirements for inclusion were radiologically proven modified Hinchey Ia/b diverticulitis, American Society of Anesthesiologists class I–III and the ability to tolerate an unrestricted diet. Exclusion criteria were the use of antibiotics and suspicion of inflammatory bowel disease or malignancy. All included patients were advised to take an unrestricted diet. The primary outcome parameter was morbidity. Secondary outcome measures were the development of recurrence and ongoing symptoms.ResultsThere were 86 patients including 37 (43.0%) men. All patients were confirmed to have taken an unrestricted diet. There were nine adverse events in seven patients. These consisted of readmission for pain (five), recurrent diverticulitis (one) and surgery (three) for ongoing symptoms (two) and Hinchey Stage III (one). Seventeen (19.8%) patients experienced continuing symptoms 6 months after the initial episode and 4 (4.7%) experienced recurrent diverticulitis.ConclusionThe incidence of complications among patients taking an unrestricted diet during an initial acute uncomplicated episode of diverticulitis was in line with that reported in the literature.