bluuebunny/crossref_metadata_2025_split huggingface dataset:
Um rosto na areia: o sujeito em Foucault
Authors: Campos Tamara De Souza , Castro Ronaldo Oliveira de 
Published: December 2017

Com base na crítica de Spivak a Foucault, discute-se a questão do sujeito na obra de Foucault, a fim de mostrar sua conexão com a perspectiva estruturalista que visava a superar o primado do sujeito autoconsciente nas Ciências humanas recorrendo a estruturas inconscientes como fundamento da explicação. Sustenta-se que essa perspectiva “antiantropocêntrica” permanece presente na obra do autor no período de Vigiar e punir e A vontade de saber. Por fim, propõe-se que as alterações na abordagem de Foucault no início dos anos de 1980 decorriam de uma tentativa de escapar de impasses que a recusa à perspectiva do sujeito soberano e autoconsciente teria acarretado
Lulism and the Institutionalization of Social Movements in Brazil: Strengthening Democratic Inclusion and Perpetuating Hegemony
Authors: Nogueira Aico Sipriano 
Published: December 2017

Este artigo avalia o potencial democratizador da institucionalização dos movimentos sociais no Brasil sob o governo Lula, a fim de avaliar seu impacto na hegemonia política e na inclusão social quando estabelecem vínculos estreitos com o aparelho estatal. Tendo como foco os movimentos sociais rurais e o Programa de Desenvolvimento Sustentável dos Territórios Rurais (Pronat), é demonstrado que a institucionalização de parte significativa dos movimentos rurais faz parte de um fenômeno social conhecido como Lulismo, uma aliança de classes sociais na qual os movimentos sociais desempenharam um papel proeminente, e que permitiu ao governo Lula consolidar seu poder. O argumento central do trabalho é que os movimentos sociais rurais, ao mesmo tempo que converteram suas demandas em políticas públicas, e fortaleceram a participação política, também perpetuaram a hegemonia de classes legitimando a autoridade do governo
Elites no Reino Unido: novas abordagens para divisões de classe contemporâneas
Authors: Hey Ana Paula , Grimaldi-Christensen Anna , Savage Mike 
Published: December 2017

O objetivo do artigo é demonstrar as “novas” elites que emergem no Reino Unido no contexto econômico, político e social do neoliberalismo. Para tal, utilizam-se os amplos trabalhos de Mike Savage acerca do significado do estudo de elites para as formas contemporâneas das divisões sociais. Os dados do Great British Class Survey servem de base para este autor delinear os elementos sociológicos centrais da composição destas elites da financeirização. Descrevem-se as clivagens em termos de mobilidade social, educação, localização e politização geradas pela concentração de distintos tipos de capital (econômico, social e cultural). A partir da especificidade britânica, pretende-se contribuir para o desenvolvimento da sociologia das elites tanto na discussão de novas perspectivas quanto nos limites e possibilidades da abordagem em diferentes contextos geográficos, políticos e sociais
A participação feminina em mercados ilícitos de drogas no Vale do São Francisco, no Nordeste brasileiro
Authors: Fraga Paulo César Pontes , Silva Joyce Keli Do Nascimento 
Published: December 2017

O artigo propõe-se a fazer reflexões com base em dados de pesquisas que analisam a participação feminina nos crimes de drogas em cidades do Submédio e Médio São Francisco, no Nordeste brasileiro. Destacamos a análise do relato de vida de seis mulheres que estiveram envolvidas no comércio ilegal de drogas e no plantio de cannabis sativa. O objetivo é contribuir para a discussão teórica sobre as relações existentes entre a condição de gênero e os mecanismos, as práticas e os atores dos mercados ilícitos de drogas na região, bem como analisar dois aspectos relacionados à gestão dos ilegalismos atrelados às drogas em contextos distintos: a qualidade da participação feminina nas atividades de plantio e de tráfico e os efeitos diferenciados produzidos nessas atividades para as mulheres em cidades do sertão baiano e pernambucano.
Rootstock effect on tree-ring traits in grapevine under a climate change scenario
Authors: De Micco Veronica , Zalloni Enrica , Battipaglia Giovanna , Erbaggio Arturo , Scognamiglio Pasquale , Caputo Rosanna , Cirillo Chiara 
Published: December 2017

ABSTRACTProjected changes in drought occurrence in the Mediterranean region are raising concerns about the adaptive capability of rainfed crops, such as grapevine, to increasing aridity. Cultivation management, especially the techniques influencing the hydraulic pathway, can play a role in plant adaptation to drought for the consequent changes in wood anatomical functional traits. The aim of this study was to assess the effect of grafting on wood anatomy in tree-ring series ofVitis vini-feraL. ‘Piedirosso’ grapevine cultivated in a volcanic area in Southern Italy. Tree-ring anatomy was analysed in vines grown on their own roots or grafted onto 420A rootstock. Results showed that grafted vines had a higher occurrence of wood traits linked with safety of water transport if compared with non-grafted vines. Grafting induced the formation of tree rings with higher incidence of latewood also characterised by narrower and more frequent vessels if compared with non-grafted vines. This study suggested a different regulation of water flow in the grafted and non-grafted vines. Such findings support the analysis of wood anatomy as a tool to drive decisions linked with plant cultivation management. In this specific case, our results encourage to further explore the change from a traditional cultivation with own-rooted grapevines towards grafted models inducing better xylem adaptation to increasing drought.
The Relationship between unclos and imo Instruments
Authors: Beckman Robert , Sun Zhen 
Published: December 2017

The 1982 United Nations Convention on the Law of the Sea (unclos) is widely viewed as a “constitutive” instrument that provides a legal framework that is being filled in, rounded out and complemented by existing and subsequently enacted international agreements and customary international law. The International Maritime Organization (imo) is the preeminent international organization with competence to establish international rules and standards for the safety, security and environmental performance of international shipping. In other words, on matters relating to international shipping, unclos outlines the rights and obligations of States parties in various maritime zones that must be exercised and fulfilled through implementation instruments under the auspices of imo.
This article will examine and discuss the relationship between unclos and imo instruments. First, it will provide an overview of imo, including its historical background, its mandates and structure, and the major instruments that are under its auspices. It will then look at the relationship between unclos and imo, and discuss how imo and its instruments have been incorporated into unclos. Furthermore, it will discuss the role of imo and its instruments in assisting States to exercise their rights and fulfil their obligations under unclos.
Three new species of Graphidaceae (lichenized Ascomycota) from the semi-arid region of northeast Brazil
Authors: DANTAS JACIELE DE OLIVEIRA , ALVES ELAINE SANTOS , LÜCKING ROBERT , CÁCERES MARCELA EUGENIA DA SILVA 
Published: December 2017

Three new lichenized fungal species in the family Graphidaceae are described from Northeast Brazil. Graphis alba has lirellae with a conspicuous white cover, eventually becoming striate, small, (sub-)muriform ascospores, and stictic acid. Halegrapha redonographoides features somewhat pseudostromatic ascomata with immersed lirellae, a completely carbonized excipulum, and small, submuriform ascospores, in combination with a norstictic acid chemistry. Thelotrema pachysporoides has an ecorticate, white thallus and produces brown, 7–13-septate, 25–35 × 7–10 µm large ascospores. The new species were found in an isolated remnant of Caatinga vegetation, at Fazenda Santa Maria da Lage, Poço Verde, Sergipe state, with additional material of one of the species also detected in the state of Tocantins.
Achieving Informed Consent for Cellular Therapies: A Preclinical Translational Research Perspective on Regulations versus a Dose of Reality
Authors: Anderson Aileen J. , Cummings Brian J. 
Published: December 2017

A central principle of bioethics is “subject autonomy,” the acknowledgement of the primacy of the informed consent of the subject of research. Autonomy requires informed consent — the assurance that the research participant is informed about the possible risks and benefits of the research. In fact, informed consent is difficult when a single drug is being tested, although subjects have a baseline understanding of the testing of a pharmacological agent and the understanding that they can stop taking the drug if there were an adverse event. However, informed consent is even less easily achieved in the modern arena of complex new molecular and cellular therapies. In this article, we argue that as science confronts new issues such as transplantation of stem cell products, which may live within the participant for the rest of their lives, researchers must carefully consider and constantly re-examine how they properly inform subjects considering participation trials of these novel therapeutic strategies.For example, the manufacture of a vial of a cell product that consists of a collection of growing cells is very different than the production of a vial of identical pills, which can be presumed to be identical. The scientific concepts on which these cellular approaches are based may seem alien and incomprehensible to a research subject, who thinks of a clinical trial as simply the selection and testing of the most efficacious pharmaceutical agent already proven to work in preclinical animal studies. The research subject would be wrong.
Clinicopathologic consensus study of gray zone lymphoma with features intermediate between DLBCL and classical HL
Authors: Pilichowska Monika , Pittaluga Stefania , Ferry Judith A. , Hemminger Jessica , Chang Hong , Kanakry Jennifer A. , Sehn Laurie H. , Feldman Tatyana , Abramson Jeremy S. , Kritharis Athena , Hernandez-Ilizaliturri Francisco J. , Lossos Izidore S. , Press Oliver W. , Fenske Timothy S. , Friedberg Jonathan W. , Vose Julie M. , Blum Kristie A. , Jagadeesh Deepa , Woda Bruce , Gupta Gaurav K. , Gascoyne Randy D. , Jaffe Elaine S. , Evens Andrew M. 
Published: December 2017

Key PointsAccurate GZL diagnosis remains challenging, with >60% of patients with presumed GZL having the diagnosis reclassified on consensus review. Treatment with DLBCL-based therapy appears most effective for GZL (including R-CHOP); however, new therapies are needed to improve outcomes.
Natural History of Contralateral Nodules After Lobectomy in Patients With Papillary Thyroid Carcinoma
Authors: Ritter Amit , Bachar Gideon , Hirsch Dania , Benbassat Carlos , Katz Orna , Kochen Nadav , Diker-Cohen Talia , Akirov Amit , Shimon Ilan , Robenshtok Eyal 
Published: December 2017

Abstract

Background
Bilateral thyroid nodularity is considered an indication for total thyroidectomy in papillary thyroid carcinoma (PTC). However, the natural history and outcome of contralateral nodules have never been studied.

Objective
To investigate the natural history of nonsuspicious contralateral nodules after lobectomy for PTC.

Methods
We included patients who had one or more solid nodules (≥3 mm) in the contralateral lobe with benign cytology before surgery or small nonsuspicious nodules per ultrasonography.

Results
One hundred and twelve patients were included. Median age was 57 years, and median size of the PTC (initial lobectomy) was 8 mm (range, 0.5 to 28 mm). On the contralateral side, the median size of nodules was 7 mm (range, 3 to 30 mm). Thirty-three nodules (29%) had fine-needle aspiration (FNA) before surgery, and all were benign. After a median follow-up of 6 years, median growth was zero (range, −20 to 19 mm). Twenty-six nodules (23%) increased ≥3 mm in size (median, 6 mm; range, 4 to 19 mm). Twenty patients (18%) developed new nodules. Twelve patients (11%) underwent completion thyroidectomy for growth (three), suspicious FNA (seven; Bethesda III to V), malignancy (one), or unknown reason (one). Overall, according to the completion thyroidectomy specimen, six patients (5%) were diagnosed with contralateral PTC (five micro-PTCs, one 20 mm), and all were without evidence of disease at the end of follow-up. There were no surgical difficulties or local complications during completion surgery.

Conclusions
Lobectomy for low-risk patients with a small PTC and nonsuspicious contralateral thyroid nodule(s) is a reliable and safe initial treatment option. In the few patients who required completion thyroidectomy, treatment with surgery and radioiodine was effective.
Primary Ovarian Insufficiency and Azoospermia in Carriers of a Homozygous PSMC3IP Stop Gain Mutation
Authors: Al-Agha Abdulmoein Eid , Ahmed Ihab Abdulhamed , Nuebel Esther , Moriwaki Mika , Moore Barry , Peacock Katherine A , Mosbruger Tim , Neklason Deborah W , Jorde Lynn B , Yandell Mark , Welt Corrine K 
Published: December 2017

Abstract

Context
The etiology of primary ovarian insufficiency (POI) remains unknown in most cases.

Objective
We sought to identify the genes causing POI.

Design
The study was a familial genetic study.

Setting
The study was performed at two academic institutions.

Patients
We identified a consanguineous Yemeni family in which four daughters had POI. A brother had azoospermia.

Intervention
DNA was subjected to whole genome sequencing. Shared regions of homozygosity were identified using Truploidy and prioritized using the Variant Annotation, Analysis, and Search Tool with control data from 387 healthy subjects. Imaging and quantification of protein localization and mitochondrial function were examined in cell lines.

Main Outcome
Homozygous recessive gene variants shared by the four sisters.

Results
The sisters shared a homozygous stop gain mutation in exon 6 of PSMC3IP (c.489 C&gt;G, p.Tyr163Ter) and a missense variant in exon 1 of CLPP (c.100C&gt;T, p.Pro34Ser). The affected brother also carried the homozygous PSMC3IP mutation. Functional studies demonstrated mitochondrial fragmentation in cells infected with the CLPP mutation. However, no abnormality was found in mitochondrial targeting or respiration.

Conclusions
The PSMC3IP mutation provides additional evidence that mutations in meiotic homologous recombination and DNA repair genes result in distinct female and male reproductive phenotypes, including delayed puberty and primary amenorrhea caused by POI (XX gonadal dysgenesis) in females but isolated azoospermia with normal pubertal development in males. The findings also suggest that the N-terminal missense mutation in CLPP does not cause substantial mitochondrial dysfunction or contribute to ovarian insufficiency in an oligogenic manner.
Differentiation between phyllodes tumours and fibroadenomas using intravoxel incoherent motion magnetic resonance imaging: comparison with conventional diffusion-weighted imaging
Authors: Kawashima Hiroko , Miyati Tosiaki , Ohno Naoki , Ohno Masako , Inokuchi Masafumi , Ikeda Hiroko , Gabata Toshifumi 
Published: December 2017

Objective:
To investigate whether the parameters derived from intravoxel incoherent motion (IVIM) MRI could differentiate phyllodes tumours (PTs) from fibroadenomas (FAs) by comparing the apparent diffusion coefficient (ADC) values.

Methods:
This retrospective study included 7 FAs, 10 benign PTs (BPTs), 4 borderline PTs, and one malignant PT. Biexponential analyses of IVIM were performed using a 3 T MRI scanner. Quantitative IVIM parameters [pure diffusion coefficient (D), perfusion-related diffusion coefficient (D*), and fraction (f)] were calculated. The ADC was also calculated using monoexponential fitting.

Results:
The D and ADC values showed an increasing tendency in the order of FA, BPT, and borderline or malignant PT (BMPT). No significant difference was found in the D value among the three groups. The ADC value of the BMPT group was significantly higher than that of the FA group (p = 0.048). The D* value showed an increasing tendency in the order of BMPT, BPT, and FA, and the D* value of the BMPT group was significantly lower than that of the FA group (p = 0.048).

Conclusion:
The D* derived from IVIM and the ADC were helpful for differentiating between FA and BMPT.

Advances in knowledge:
IVIM MRI examination showed that the perfusion-related diffusion coefficient is lower in borderline and malignant PTs than in FAs and the opposite is true for the ADC.
Evaluation of electrochemiluminescence immunoassays for immunosuppressive drugs on the Roche cobas e411 analyzer
Authors: Fung Angela W.S. , Knauer Michael J. , Blasutig Ivan M. , Colantonio David A. , Kulasingam Vathany 
Published: December 2017

Background: Therapeutic drug monitoring of immunosuppressant drugs are used to monitor drug efficacy and toxicity and to prevent organ transplant rejection. This study evaluates the analytical performance of semi-automated electrochemiluminescence immunoassays (ECLIA) for cyclosporine (CSA), tacrolimus (TAC) and sirolimus (SRL) on the Roche cobas e 411 analyzer at a major transplant hospital to assess method suitability and limitations.Methods: Residual whole blood samples from patients undergoing immunosuppressant therapy were used for evaluation. Imprecision, linearity, functional sensitivity, method comparisons and lot-to-lot comparisons were assessed.Results: Total imprecision ranged from 3.3 to 7.1% for CSA, 3.9 to 9.4% for TAC, and 4.6 to 8.2% for SRL. Linearity was verified from 30.0 to 960.9 μg/L for CSA, from 1.1 to 27.1 μg/L for TAC, and from 0.5 to 32.3 µg/L for SRL. The functional sensitivity met the manufacturer’s claims and was determined to be <6.5 μg/L for CSA, 1.1 μg/L for TAC, and <0.1 µg/L for SRL (CV≤20%). Deming regression analysis of method comparisons with the ARCHITECT immunoassay yielded slopes of 0.917 (95%CI: 0.885-0.949) and r of 0.985 for CSA, 0.938 (95%CI: 0.895-0.981) and r of 0.974 for TAC, and 0.842 (0.810-1.110) and r of 0.982 for SRL. Deming regression analysis of comparisons with the LC–MS/MS method yielded slopes of 1.331 (95%CI: 1.167-1.496) and r of 0.969 for CSA, 0.924 (95%CI: 0.843-1.005) and r of 0.984 for TAC, and 0.971 (95%CI: 0.913-1.030) and r of 0.993 for SRL.Conclusions: The cobas e 411 ECLIA for CSA, TAC, and SRL have acceptable precision, linearity, and functional sensitivity. The method comparisons correlated well with the ARCHITECT immunoassay and LC–MS/MS and is fit for therapeutic drug monitoring
SCOTS: The Searchable Collection of Time Series
Authors: McLaren Constance H. , McLaren Bruce J. 
Published: December 2017

Instructors searching for interesting time series data to use for class illustrations or assignments can draw from the data files that accompany their text books. They can also search for data from annual reports, trade organizations, government entities, and other public sources. However, the amount of data accompanying textbooks is limited, and determining what public data might be available and then finding it is not simple, making it time consuming to find new examples for large classes or multiple offerings of a course. The search becomes more complicated for the instructor who needs to find data with specific types of trend or seasonality to illustrate concepts for students. This article presents the SCOTS master table, a searchable Excel file that provides information about and links to a curated collection of real time series data files stored in Excel format. Instructors can easily filter the list to find a time series with the kinds of features they want and download the Excel file to use in class. Many of the data files in this collection have been used for class assignments, and examples of assignment questions are included in the article. The supplement file is available at http://pubsonline.informs.org/doi/suppl/10.1287/ited.2017.0188 .
The voices of journalism and the LGBTQI movement in response to violence in same-sex couples: Towards the construction of a social problem?
Authors: Carratalá Adolfo 
Published: December 2017

Abstract
In recent years the Spanish media have highlighted numerous homicides of gay men committed by their partners or ex-partners. These homicides are classified by the term intragender violence, or violence committed in the context of a relationship between people of the same sex. Reports of these crimes have led to public debate on how society and its institutions should respond to these homicides, which several commentators have likened to partner violence against women (PVAW), the victims of which receive legal protection from government institutions. In this article we analyse the discourse that is used to refer to this issue by the two main agents involved in the construction of collective problems – social organizations and the media. By examining analytical journalistic documents (reports and opinion articles), we analyse the approaches of the LGBTQI associations cited in those documents and media discourse to identify and reconstruct the arguments used and establish similarities and differences between the stakeholders in the organizational and media spheres. Our results show that while associations and journalistic stakeholders agree that violence in same-sex couples should be considered a social problem, they disagree as to whether or not such violence should be categorized as male-based violence, similar to PVAW.
Are victims to blame? Youth, gender and moral discourse on online risk
Authors: Jorge Ana , Farrugia Lorleen 
Published: December 2017

Abstract
This article takes a discourse analysis frame to understand how young people’s norms and moral evaluations of their practices on digital media are culturally negotiated between their own and their peers’ experiences, parental concerns, awareness programmes and media representations. It draws on focus groups and interviews with 171 participants aged 13–16 from nine European countries, analysing how young people position themselves towards online experiences, particularly bullying, sexual communication and contact. While teenagers can sympathize with victims of bullying, especially if they perceive them as vulnerable, they can blame older teenagers, girls or parents for initiating or being co-responsible for risks young victims are involved in. They are judged as in failing, when they choose to not comply with self-protection and self-vigilance (Giddens 1991, Dobson and Ringrose 2015, Gill and Scharf 2011), which can be detected in young people’s moral discourses as a successful way of being and behaving online.
Representing diverse femininities on Instagram: A case study of the body-positive @effyourbeautystandards Instagram account
Authors: Caldeira Sofia P. , De Ridder Sander 
Published: December 2017

Abstract
This article focuses on a critical analysis of alternative representations of femininities on Instagram through a case study of the @effyourbeautystandards account. This body-positive account aims to promote self-love and questions beauty ideals by sharing self-representations of ‘ordinary’ women (i.e. non-models or celebrities) who feel that they do not live up to the current beauty standards. We focus on the political potential of these diverse self-representations in terms of ‘everyday activism’. @effyourbeautystandards is recognized as having an overtly political stance, adopting an intersectional approach and employing strategies of ‘empowering exhibitionism’. Yet, the article questions this more optimistic view by critically addressing the postfeminist sensibilities underlying the account, namely, its emphasis on fashion and beauty. Moreover, Instagram’s role in reproducing traditional gender norms is explored. The article analyses Instagram’s technological and sociocultural affordances, such as its Terms of Use, and the ‘editorial power’ of the users’ likes, comments and reports.