bluuebunny/crossref_metadata_2025_split huggingface dataset:
The vaginal microbiota in the first trimester of pregnancy in women having history of pregnancy loss
Authors: Siniakova Anna A. , Shipitsyna Elena V. , Rybina Elena V. , Budilovskaya Olga V. , Pluzhnikova Tamara A. , Bolotskikh Viacheslav M. , Savicheva Alevtina M. 
Published: December 2016

Introduction. Abnormal vaginal microflora in the first trimester of pregnancy is a risk factor for miscarriage. Opportunistic microorganisms predominate among microorganisms causing microflora disturbance. Aim. The aim of the study was to evaluate the vaginal microflora in the first trimesterфIntroduction. Abnormal vaginal microflora in the first trimester of pregnancy is a risk factor for miscarriage. Opportunistic microorganisms predominate among microorganisms causing microflora disturbance. Aim. The aim of the study was to evaluate the vaginal microflora in the first trimester of pregnancy in women having history of pregnancy loss. Matherials and Methods. Real-time polymerase chain reaction, microscopic and cultural methods were used to examine 60 pregnant women having history of pregnancy loss and 10 pregnant women with uncomplicated obstetric history. Results. Disorders of the vaginal microflora were observed only in women having history of pregnancy loss. The lactoflora in both groups was shown to consist most frequently of 3 Lactobacillus species: Lactobacillus crispatus, L. jensenii, and L. iners. However, the species L. iners were detected only in the group of women with history of pregnancy loss. Non-Lactobacillus microbiota was significantly more often observed in pregnant women having history of pregnancy loss. Facultative and obligate anaerobes were detected in both groups. The concentration of Ureaplasma spp. and Mycoplasma hominis in women in both groups had no significant differences. Conclusions. The results of this study indicate that abnormal microbiota is more often observed in women having history of pregnancy loss.of pregnancy in women having history of pregnancy loss. Matherials and Methods. Real-time polymerase chain reaction, microscopic and cultural methods were used to examine 60 pregnant women having history of pregnancy loss and 10 pregnant women with uncomplicated obstetric history. Results. Disorders of the vaginal microflora were observed only in women having history of pregnancy loss. The lactoflora in both groups was shown to consist most frequently of 3 Lactobacillus species: Lactobacillus crispatus, L. jensenii, and L. iners. However, the species L. iners were detected only in the group of women with history of pregnancy loss. Non-Lactobacillus microbiota was significantly more often observed in pregnant women having history of pregnancy loss. Facultative and obligate anaerobes were detected in both groups. The concentration of Ureaplasma spp. and Mycoplasma hominis in women in both groups had no significant differences. Conclusions. The results of this study indicate that abnormal microbiota is more often observed in women having history of pregnancy loss.
Evaluation of significant bacteriuria in pregnant women using quantitative real-time PCR
Authors: Khusnutdinova Tatyana A. , Shipitsina Elena V , Savochkina Yulia A. , Timoshina Olga Yu. , Rybina Elena V. , Gushchin Alexander E. , Savicheva Alevtina M. 
Published: December 2016

Introduction. Urinary tract infections are the most common infections in obstetrics and gynecology. Bacteriological method to investigate urine is laborious and time-consuming, therefore development of accurate and rapid methods for the detection of significant bacteriuria is important. Objective. Evaluation of quantitative real-time PCR based approach for the detection of significant bacteriuria in pregnant women. Material and methods. A retrospective investigation of mid-stream urine samples obtained from pregnant women was performed. Urine culture was performed using quantitative method, and a case was considered as significant bacteriuria if ≥ 105 CFU/ml were detected. Urine samples were analyzed for main uropathogens / groups of uropathogens using quantitative multiplex real-time PCR. Diagnostic characteristics of PCR were computed relative to the results of urine culture. Results. In total, 896 urine samples were tested. Of them, significant bacteriuria was found in 28 cases (3%). The frequency of detection of Escherichia coli was 50%, Enterococcus spp. — 25%, Klebsiella spp. — 7%, Proteus spp. and S. saprophyticus 4% each, Streptococcus spp. — 14%. Sensitivity and specificity of the detection of significant bacteriuria using quantitative real-time PCR for the majority of bacterial species / groups were 99% to 100%. Sensitivity and specificity of the quantitative real-time PCR based method were 96% and 98%, respectively. Conclusions. Prevalence of significant bacteriuria among pregnant women is 3%. Half of the uropathogens isolated from pregnant women with bacteriuria are E. coli. Sensitivity and specificity of quantitative PCR for the detection of significant bacteriuria are 96% and 98%, respectively.
Incidence of chronic rhinosinusitis in chronic headache: diagnostic criteria
Authors: Chandrashekar Shilpa , S. Sandeep , Shivaram Shetty T. , Balakrishna Rakesh 
Published: December 2016

<p class="abstract"><strong>Background:</strong> Chronic rhinosinusitis and vascular headache share similar signs and symptoms, which includes nasal symptoms, facial pain and headache. The aim of the study was to evaluate incidence of chronic rhinosinusitis in patient with vascular headache<span lang="EN-IN">. </span></p><p class="abstract"><strong>Methods:</strong> A group of 100 patients aged between 25-45 who presented to our OPD with complaint of headache were included in our study. Patients were assessed with rhinosinusitis disability index (RSDI) for major and minor criteria of rhinosinusitis<span lang="EN-IN">. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">The criteria of the American Academy of Otolaryngology—Head and Neck Surgery were applied to diagnose 82 cases of headache attributed to chronic rhinosinusitis. </span>Out of 100 subjects who were asked to fill the rhinosinusitis disability index 70 subjects (34 men and 36 female) had functional score (F) of 0- 45, physical score (P) of 0-35 and emotional score (E) of 0-25 and total score of 0-105, whereas 12 subjects (5 men and 7 female) had functional score (F) of 0-22, physical score (P) of 0-30 and emotional score (E) of 0-20 and a total score of 0-72.</p><p class="abstract"><strong>Conclusions:</strong> Out of total 100 patients with headache (62 men and 38 female), 82 subjects (54 male and 28 female) had chronic rhinosinusitis and 18 (10 men and 8 female) had vascular headache<span lang="EN-IN">.</span></p>
Articulación de sectores y crecimiento económico en Colombia: un enfoque multivariado de detección de clusters empleando un Modelo de Insumo Producto
Authors: Gaytán Alfaro Edgar David , Ramos Mallarino Juan Carlos 
Published: December 2016

<p>Considerando como base de información a la Matriz Insumo Producto para la economía colombiana de 2010, actualizada por el Departamento Administrativo Nacional de Estadística (DANE, 2013), el presente documento emprende un proceso multivariante de reducción de datos sobre la submatriz de flujos intersectoriales con el objeto de presentar componentes principales derivados de la intensidad de comercialización intermedia. Tales componentes representan <em>clusters</em> cuya definición proviene de la intensidad de los intercambios sostenidos en las actividades económicas participantes. Los resultados pretenden convertirse en un referente de la complejidad productiva de Colombia cuya aplicación se traduzca en el desarrollo de un esquema normativo de cohesión y articulación del aparato productivo como factores de crecimiento económico.</p>
Coopercuc: percursos de valorização dos recursos locais e de convivência com o Semiárido
Authors: Gentile Chiara , Burgos Andrés 
Published: December 2016

Dentro do contexto de apropriação discursiva da convivência com o semiárido brasileiro, a história e a evolução da experiência da Cooperativa Agropecuária Familiar de Canudos, Uauá e Curaçá (Coopercuc), BA, exemplificam a afirmação exitosa de eventos e processos sociais e culturais aptos para reverter os efeitos de alguns dos fatores históricos e sociopolíticos associados Ã s principais fragilidades dessa região. Diante disso, este estudo tem o objetivo de examinar o sentido de convivência com o semiárido a partir da análise dessa experiência de agricultura familiar e prática de desenvolvimento rural no semiárido. Para atingir o objetivo, foi realizada uma pesquisa exploratória por meio de visitas de campo, entrevistas semiestruturadas e coleta de dados qualitativos, visando Ã reconstrução da história da cooperativa e Ã avaliação de seus efeitos. As conclusões apontam para processos, agentes e resultados que constroem uma experiência situada de desenvolvimento que, por gerar caminhos possíveis de mudança e benefícios duradouros integrados com o tecido social local, pode ser considerada virtuosa.
contribuição da Bioágua para a segurança alimentar e sustentabilidade no Semiárido Potiguar brasileiro
Authors: Santos Christiane Fernandes dos , Maia Zildenice Matias Guedes , Siqueira Elisabete Stradiotto , Souza Cimone Rozendo de 
Published: December 2016

No semiárido potiguar brasileiro a má distribuição das chuvas compromete a sustentabilidade e a segurança alimentar dos agricultores familiares. Pesquisar sustentabilidade nessa região é se deparar com a necessidade de otimização da produção de alimentos, por meio do reúso da água. Logo, o presente estudo objetivou avaliar o Programa Bioágua Familiar, quanto Ã segurança alimentar e Ã sustentabilidade das famílias experimentadoras. Realizaram-se entrevistas com quatro agricultores das comunidades de Arrimo e Reforma, localizadas na zona rural do município de Janduís/RN. A tecnologia Bioágua Familiar aumenta o acesso Ã água, permitindo uma produção constante de frutas e hortaliças para o consumo familiar. Porém, a pesquisa revelou que a água cinza gerada é insuficiente para manter o sistema. A difusão dessa tecnologia depende de um conjunto de estratégias de convivência com o semiárido. Apreende-se que o Bioágua raramente poderá, sozinho, se constituir como alternativa sustentável para a produção de alimentos.
Convivência com a escassez de água: a importância do capital social nas áreas susceptíveis Ã desertificação no Semiárido
Authors: FAUSTINO JENNIFER CICERA DOS SANTOS , Lima Patrícia Verônica Pinheiro Sales de , Casimiro Filho Francisco , Rodrigues Maria Ivoneide Vital 
Published: December 2016

Este artigo objetiva analisar como os indicadores de capital social se relacionam com a percepção dos líderes de comunidades rurais quanto Ã sua capacidade de conviver com a escassez de água decorrente das secas periódicas na região semiárida. Para tanto, optou-se por um estudo empírico nas comunidades rurais em Áreas Susceptíveis Ã Desertificação (ASDs) da Paraíba. Como métodos de análise, foram adotadas técnicas de estatística descritiva, construção de um índice de capital social e coeficiente eta para análise de relação entre variáveis. Os principais resultados mostraram que, de acordo com as lideranças locais, as comunidades apresentam baixo nível de capital social e se encontram com baixa capacidade de conviver com a escassez de água apesar das tecnologias sociais aí existentes. A análise da relação entre essas duas variáveis mostrou a necessidade de investimentos na dotação de capital social como forma de aumentar o desempenho das comunidades rurais no enfrentamento das restrições hídricas nas ASDs paraibanas.
Tecnologias sociais no Rio Grande do Norte: algumas discussões sobre a convivência com o Semiárido
Authors: Silva Valdenildo Pedro da , Barros Evelyn Christie Nascimento de 
Published: December 2016

As tecnologias sociais (TSs) têm se constituído em uma ferramenta de poder, uma vez que carregam um forte apelo de quebra do paradigma entre o combate Ã s secas e a convivência com o semiárido. Contudo, as discussões e as considerações acerca das principais TSs de convivência com o semiárido são diminutas. Sabe-se pouco sobre as mais produzidas e mais significativas; onde estão sendo implementadas; quem as implementa; que contribuições vêm dando Ã conservação da natureza, Ã sobrevivência, Ã manutenção e Ã convivência de moradores com o semiárido de maneira geral e, em particular, do estado do Rio Grande do Norte. Portanto, o estudo em tela objetivou discutir as principais tecnologias sociais, desenvolvidas e utilizadas pelas populações, que contribuem para a convivência com o semiárido do Rio Grande do Norte. Para a consecução do estudo, no que concerne Ã s TSs, foram realizados levantamentos bibliográficos e documentais, bem como entrevistas (por meio de telefonemas para os responsáveis de órgãos ou instituições parceiras na construção de TS no semiárido), visando a obter informações sobre sua aplicabilidade, sua frequência, seu método construtivo e suas principais contribuições. Os resultados obtidos expressam que as TSs mais produzidas e difundidas pelo semiárido do Rio Grande do Norte estão voltadas para a coleta e o armazenamento de água de chuva, entre as quais se destacam a cisterna-calçadão, a cisterna-enxurrada, a barragem subterrânea, o barreiro trincheira, a barraginha, o tanque de pedra e a bomba popular. Essas TSs contribuem para que se tenha uma convivência com o semiárido no que se refere Ã captação e ao armazenamento de água. No entanto, o problema do acesso Ã s TSs e a busca por uma melhor convivência, por meio de políticas públicas mais duradouras, continuam como desafios a serem superados por alguns segmentos.
O plano municipal de convivência com o Semiárido como instrumento discursivo:
Authors: Sieber Shana Sampaio , Gomes Ramonildes Alves 
Published: December 2016

O objetivo deste artigo é refletir sobre o processo de legitimação do paradigma da convivência com o semiárido por meio da análise da construção de um Plano Municipal de Convivência, no município de Serra Talhada (Sertão de Pernambuco), em 2014. O exercício metodológico privilegiou a observação de eventos, a análise de documentos e entrevistas com atores diversos, que acessavam a temática da convivência no seu campo de atuação. Os resultados demonstraram que o discurso da convivência é enunciado pelo protagonismo da sociedade civil, mas na prática experimenta uma confluência perversa com o Estado, reduzindo princípios de transformação social Ã reprodução de velhas práticas de combate Ã seca. A configuração de um Plano Municipal parece funcionar como instrumento discursivo para legitimar as ações do Estado, em torno de um paradigma que nada mais é do que um projeto político de modernização para o semiárido.
Gene Set to Diseases (GS2D): disease enrichment analysis on human gene sets with literature data
Authors: Fontaine Jean Fred , Andrade-Navarro Miguel A 
Published: December 2016

Large sets of candidate genes derived from high-throughput biological experiments can be characterized by functional enrichment analysis. The analysis consists of comparing the functions of one gene set against that of a background gene set. Then, functions related to a significant number of genes in the gene set are expected to be relevant. Web tools offering disease enrichment analysis on gene sets are often based on gene-disease associations from manually curated or experimental data that is accurate but does not cover all diseases discussed in the literature. Using associations automatically derived from literature data could be a cost effective method to improve the coverage of diseases for enrichment analysis at comparable levels of accuracy.
We have implemented a method named Gene set to Diseases, GS2D, as a web tool performing disease enrichment analysis on human protein coding gene sets. It uses an automatically built dataset of more than 63 thousand gene-disease associations defined as statistically significant co-occurrences of genes and diseases in annotations of biomedical citations from PubMed. The dataset covers more diseases for enrichment analysis than the largest comparable curated database, Comparative Toxicogenomics Database, and its performance compared favourably to similar approaches based on manually curated or experimental data. Graphical and programmatic interfaces are available at http://cbdm.uni-mainz.de/geneset2diseases.
Perspectivas de formação: diálogo entre crescimento e o cultivo de si
Authors: Ali Thaís Ferreira , Hardt Lúcia Schneider , Moura Rosana Silva de 
Published: December 2016

O artigo apresenta o pensamento de Dewey sustentando a tese de que formação é crescimento em função de uma efetiva relação com a vida: o humano é exigido pela vida a desenvolver-se, a crescer em direções muito diversas para então ocupar um espaço na sociedade. No intuito de gerar uma reflexão sobre o dilema da formação humana, o texto introduz outro autor, como coadjuvante, pondo em diálogo duas perspectivas implicadas pelo mesmo tema.
Hydrometric network design using dual entropy multi-objective optimization in the Ottawa River Basin
Authors: Werstuck Connor , Coulibaly Paulin 
Published: December 2016

AbstractWater resources managers commonly rely on information collected by hydrometric networks without clear knowledge of their efficiency. Optimal water monitoring networks are still scarce especially in the Canadian context. Herein, a dual entropy multi-objective optimization (DEMO) method uses information theory to identify locations where the addition of a hydrometric station would optimally complement the information content of an existing network. This research explores the utility of transinformation (TI) analysis, which can quantitatively measure the contribution of unique information from a hydrometric station. When used in conjunction, these methods provide an objective measure of network efficiency, and allow the user to make recommendations to improve existing hydrometric networks. A technique for identifying and dealing with regulated basins and their related bias on streamflow regionalization is also examined. The Ottawa River Basin, a large Canadian watershed with a number of regulated hydroelectric dams, was selected for the experiment. The TI analysis approach provides preliminary information which is supported by DEMO results. Regionalization was shown to be more accurate when the regulated basin stations were omitted using leave one out cross validation. DEMO analysis was performed with these improvements and successfully identified optimal locations for new hydrometric stations in the Ottawa River Basin.
The Promotion of Cross-Border Medical Tourism in Developing Countries: Economic Growth at the Expense of Healthcare System Efficiency and Cost Containment?
Authors: Phua Kai-Lit 
Published: December 2016

Background:More and more developing nations are promoting cross-border medical tourism as a way to enhance economic growth. Major destinations for medical tourism in South and Southeast Asia include India, Thailand, Malaysia and wealthy Singapore. Much has been written on the pros and cons of the growth of medical tourism for both destination and source countries. This article uses a different approach.Methodology:Examples from India, Thailand and Malaysia are used to discuss the actual and potential impact of medical tourism on healthcare system efficiency and costs.Results and Conclusions:Based on the experience of these three countries, it is argued that the promotion of cross-border medical tourism to enhance economic growth is likely to be at the expense of national healthcare system efficiency as it goes directly against cost containment strategies and measures.
Pengembangan soal matematika model PISA menggunakan Konteks Jambi
Authors: Charmila Ninik , Zulkardi Zulkardi , Darmawijoyo Darmawijoyo 
Published: December 2016

Penelitian ini bertujuan untuk menghasilkan soal matematika model PISA untuk siswa SMP menggunakan konteks Jambi yang valid, praktis, dan memiliki efek potensial. Metode penelitian yang digunakan adalah Design research tipe development study. Analisis data adalah analisis deskriptif. Hasil penelitian berupa seperangkat soal matematika model PISA menggunakan konteks Jambi yang valid, praktis dan memlilki efek potensial sebanyak 14 butir soal. Valid dari segi konten, konstruk, dan bahasa berdasarkan penilaian validator, praktis berdasarkan uji coba small group dan memiliki efek potensial berdasarkan analisis hasil jawaban siswa dan angket pada field test. Bedasarkan hasil analisis diperoleh bahwa soal yang dikembangkan memiliki beberapa efek potensial, yaitu memunculkan pelibatan kemampuan dasar matematis yang beragam pada proses penyelesaiannya. Selain itu, juga mampu menarik minat dan memotivasi siswa sehingga tertantang menyelesaikan soal. Soal-soal ini juga memberikan stimulus kepada siswa untuk berpikir kritis menggunakan penalaran sendiri dalam penyelesaiannya.Kata kunci: research and development, development study, PISA, Konteks Jambi DEVELOPING MATHEMATIC QUESTIONS OF PISA MODEL BY USING JAMVI CONTEXT AbstractThe aim of this research was to provide valid, practical mathematic questions of PISA model for SMP students by using Jambi contex, and have potential effect. The method of the research was developmental research design . Descriptive analysis was used to analyze the data. The result of the research was a set of valid, practical 14 mathematic questions of PISA model in Jambi contex, and having potential effect. The validity of content, construct, and language was based on expert judgment, the practicality was measured in small group, and the potential effect was based on analysis of student answers and questionnaires in field test. The result of analysis showed that the developed questions had several potential effects such as inviting students’ various basic skills of mathematic in the process of answering the questions. Besides that, it could encourage students’ ability and motivate students to answer and finish the questions. These questions also attract the students to use their critical thinking ability to answer the questions.Keywords: research and development, development study, PISA, Jambi context