bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of Opuntia ficus‐indica juice supplementation on oxidative stress, cardiovascular parameters, and biochemical markers following yo‐yo Intermittent recovery test
Authors: Khouloud Aloui , Abedelmalek Salma , Chtourou Hamdi , Souissi Nizar 
Published: December 2017

AbstractThe aim of the study was to investigate the effect of a flavonoid‐rich fresh fruit juice on cardiovascular, oxidative stress, and biochemical parameters during the yo‐yo intermittent recovery test (YYIRT). Twenty‐two healthy males subjects participated in this study divided into two groups: An experimental group (EG: n = 11) who consumed the antioxidant supplement and a control group (CG: n = 11). All participants performed two test sessions at 07:00 hr before and after 2 weeks of supplementation with Opuntia ficus‐indica juice. Blood samples were taken before (P1) and immediately (P2) after the YYIRT. Our results showed that following the 2,2‐diphenyl‐1‐ picrylhydrazyl (DPPH●) test, the Opuntia ficus‐indica juice has an antioxidant capacity for capturing free radicals (p < .05) and reducing oxidative stress related to exercise. Concerning biochemical and cardiovascular parameters, our results showed a significant increase on total cholesterol (TC) (p < .01), triglycerides (TG) (p < .05), high‐density lipoprotein (HDL) (p < .01), low‐density lipoprotein (LDL) (p < .01), creatine kinase (CK) (p < .01), lactate deshydrogenase (LDH) (p < .01), glucose (GLC) (p < .01), systolic (SBP), and diastolic blood pressure (DBP) (p < .01) immediately after exercise. However, TC (p < .05), TG (p < .05) and LDL (p < .05), the maximal heart rate (HRmax), the CK (p < .05), and LDH (p < .01) as well as the malondialdehyde (MDA) (p < .01) demonstrated a significant decrease after supplementation of Opuntia ficus‐indica juice before and immediately after YYIRT. However, no significant effect on HDL (p > .05), GLC (p > .05) levels nor the SBP and DBP (p > .05) was observed after supplementation with Opuntia ficus‐indica juice. The supplementation leads to an improvement on YYIRT performance (The total distance covered during the YYIRT, VO2max, VMA) and the rating of perceived exertion (RPE). Opuntia ficus‐indica juice has a potent antioxidant activity that reduces total and LDL‐cholesterol with only a moderate lowering of HDL‐cholesterol and oxidative stress. Moreover, supplementation decreases muscle damage caused by the endurance exercise.
Application of GUSED‐VBS 2 Model for Flow and Sediment Transport in Vegetated Strips to Improve Water Quality
Authors: Akram Sina , Yu Bofu 
Published: December 2017

AbstractVegetated buffer strips change flow hydrology and sediment transport by increasing resistance to the flow and intensifying infiltration. GUSED‐VBS 2 is a process‐based mathematical model developed to simulate flow characteristics and the fate and transport of sediment in the backwater region upstream of vegetated strips and within them. The model also predicts the concentration and delivery of different particle sizes leaving the vegetated strips and reaching open water bodies. GUSED‐VBS 2 assumes that entrainment and deposition processes occur simultaneously and uses the Green–Ampt approach to simulate infiltration and gradually varied flow and kinematic wave approximation to simulate the water profile in the backwater region and within the vegetated strip respectively. The modified GUEST model approach was used to model the fate and transport of sediment in vegetated strips. Field data were used to evaluate the model predictions of the efficiency of vegetated strips in reducing runoff, sediment concentration and sediment delivery, and the results showed that GUSED‐VBS 2 performed much better in controlled conditions compared to field conditions. The performance of the GUSED‐VBS 2 and WEPP models in simulating particle size distribution in the outflow was compared with different model evaluation criteria and GUSED‐VBS 2 showed better performance compared to WEPP. Copyright © 2017 John Wiley & Sons, Ltd.
Enhancing knowledge of authorization requests through registry development
Authors: Kuntz‐Melcavage Kara L. , Gahagan Kyle DeCarlo , Fracasso Mark R. , Marsteller Jill A. 
Published: December 2017

AbstractUnderstanding the member population to which medical coverage policies apply is important for ensuring the relevance of a health insurer's policies. The medical policy unit of our company developed a registry and workflow to enhance our knowledge about the members who seek authorization for bariatric surgery. Data captured in the registry have allowed us to construct a descriptive profile of the entire population that seeks bariatric surgery (both members who are approved and members who are denied). In addition, we have examined characteristics associated with denied authorization requests, determined the proportion of requests originating from specific insurance products, and studied the relationship between results on a specific laboratory test and authorization decisions. Given the growing importance of data in the realm of health care management, this article is an important demonstration of how data can be used to understand populations of members who are affected by medical policies.
UV‐Triggered Optical Response and Oxygen Scavenging Ability of a Water‐Soluble Poly(N,N‐dimethylacrylamide‐co‐2‐vinylbenzylanthraquinone) Copolymer
Authors: Karamitrou Melpo , Voyiatzis George A. , Kallitsis Joannis K. , Bokias Georgios 
Published: December 2017

AbstractA vinyl‐modified anthraquinone (AQ) derivative (Vinyl‐AQ) is synthesized through a palladium‐mediated Suzuki coupling reaction between vinylphenylboronic acid and 2‐chloromethylanthraquinone and, subsequently, copolymerized with N,N‐dimethylacrylamide (DMAM) through free radical copolymerization in organic solvent. The chemical structure of the resulting water‐soluble copolymer, P(DMAM‐co‐AQ), is verified using techniques such as proton nuclear magnetic resonance, attenuated total reflection‐infrared spectroscopy, thermogravimetric analysis, and UV–vis spectroscopy. The evolution of the oxygen scavenging abilities of aqueous P(DMAM‐co‐AQ) solutions after UV irradiation is monitored as a function of UV irradiation time, concentration of AQ moieties, and pH. The copolymer is proved an effective UV‐triggered oxygen scavenger, leading to dissolved oxygen contents below 1 ppm for the optimized experimental conditions. This behavior is related with the appearance of novel chemical species with interesting optical properties, as suggested by the respective evolution of the UV–vis absorption and photoluminescence spectra after UV irradiation.
Practical Management of Fetal Obstructive Uropathy
Authors: Down Colin J. , Burns Jessica K. , Woodward Mark N. , Overton Timothy G. 
Published: December 2017

AbstractUrinary tract dilatation is commonly identified on antenatal ultrasound. It represents a wide range of aetiologies including obstructive uropathy. Antenatal diagnosis and a consistent, evidenced based approach to follow up is essential in reducing neonatal morbidity and mortality. We present a summary of the current literature and a practical guide to the management of obstructive uropathy, including the normal sonographic features of the developing fetal urinary tract, antenatal diagnostic criteria and the approach to postnatal investigation and management.
Microbleeds are associated with depressive symptoms in Alzheimer's disease
Authors: Leeuwis Anna E. , Prins Niels D. , Hooghiemstra Astrid M. , Benedictus Marije R. , Scheltens Philip , Barkhof Frederik , van der Flier Wiesje M. 
Published: December 2017

AbstractIntroductionCo‐occurrence of cerebrovascular disease and depression led to the “vascular depression hypothesis”. White matter hyperintensities (WMHs) have been associated with depressive symptoms in population‐based studies. We studied the association between small vessel disease and depressive symptoms in a memory clinic population.MethodsWe included >2000 patients with subjective cognitive decline (SCD), mild cognitive impairment, and Alzheimer's disease (AD). Magnetic resonance imaging was rated for WMHs, lacunes, and microbleeds. Depressive symptoms were assessed using the Geriatric Depression Scale. We performed logistic regression analysis.ResultsDepressive symptoms were present in AD: 17%; mild cognitive impairment: 25%; and SCD: 23%. SCD patients with WMHs showed higher propensity of depressive symptoms than AD patients with WMHs. AD patients with microbleeds were more likely to have depressive symptoms compared with AD patients without microbleeds (odds ratio = 1.70; 95% confidence interval: 1.08–2.68).DiscussionMicrobleeds are associated with depressive symptoms in AD, supporting a potential role of cerebral amyloid angiopathy in the occurrence of depressive symptoms in AD.
Optical coherence tomography findings in Parkinson's disease
Authors: Aydin Turkoglu Sule , Umit Dogan , Nur Ogun Muhammed , Fatih Ulas , Asena Keles , Nefise Ozturk Yavas , Serpil Yildiz 
Published: December 2017

AbstractThe aim of this study is to compare optical coherence tomography (OCT) findings of retinal thickness (RT) and retinal nerve fiber layer thickness (RNFLT) of idiopathic Parkinson's disease (IPD) patients to those of healthy subjects, and to investigate whether there is any relationship between the severity of the disease and the RNFLT values. This prospective study was included 25 IPD patients and 29 healthy controls. In the IPD group, the Hoehn and Yahr (H&Y), Unified Parkinson's Disease Rating Scale (UPDRS), and Mini‐Mental State Exam (MMSE) were performed. Intraocular pressure (IOP), visual acuity (VA), spherical equivalent, axial length (AL), and central corneal thickness (CCT) were measured using OCT in both groups. The RT was measured in the central retinal (RTc), nasal (RTn), and temporal (RTt) segments. Nasal (RNFLTn), nasal superior (RNFLTns), nasal inferior (RNFLTni), temporal (RNFLTt), temporal superior (RNFLTts), and temporal inferior (RNFLTti) measurements were made and mean RTFLT was calculated (RNFLTg) for each individual. In the patient group, IOP and VA values were statistically significantly lower The RTn and RNFLTg were significantly thinner in the patient group. There was no statistically significant relationship between the severity of IPD and these findings. In our study, RNFLTg and RTn were found to be thinner in the IPD group, which may have caused lower VA scores. The effects of retinal dopamine depletion on RT and RNFLT, and lower IOP values in the non‐glaucomatous IPD patients should be further investigated.
Changes in Oxygen Consumption and Heart Rate After Acute Myocardial Infarction During 6‐Month Follow‐up
Authors: Choe Yuri , Han Jae‐Young , Choi In‐Sung , Park Hyeng‐Kyu 
Published: December 2017

AbstractBackgroundExercise intensity is a particularly important determinant of physiological responses to exercise training in patients with acute myocardial infarction. Heart rate (HR) is commonly used as a practical way of prescribing and monitoring exercise as specific intensities based on a linear relationship between the percentage of maximum HR (%HRmax) and the percentage of maximum oxygen consumption (%VO2max) regardless of age, gender, or exercise mode.ObjectiveTo examine the change in variability in the correlation between %HRmax and %VO2max after acute myocardial infarction.DesignRetrospective study.SettingRegional cardio‐cerebrovascular center at a tertiary hospital.PatientsA total of 66 patients were enrolled who were referred for cardiac rehabilitation (CR) after percutaneous intervention, and who had reached stage 3 of the modified Bruce Protocol (mBP) on an exercise tolerance test (ETT).MethodsThere were 54 men and 12 women with an average age of 56.7 ± 9.48 years, ejection fraction (EF) of 56.4% ± 8.89%, and body mass index (BMI) of 24.73 ± 2.86 kg/m2. All patients participated in a 4‐week outpatient CR program and underwent ETT with a gas analyzer to determine maximal heart rate and maximal oxygen consumption before CR and 1 month, 3 months, and 6 months after CR.Main Outcome MeasurementsVO2max and HRmax were defined as the highest values attained during the ETT. The HR and VO2 values at each stage of the mBP were expressed as percentages of their maximum. %HRmax and %VO2max were calculated at each stage of the mBP.ResultsThe maximum METs and VO2max significantly improved at 1 month after CR, but not significantly at 3 and 6 months after CR. The correlation between VO2max and HRmax progressively changed in a favorable manner during CR. The relationship between %HRmax and %VO2max indicated a coefficient of variation before and 1, 3, and 6 months after of 0.800, 0.826, 0.832, and 0.880, respectively.ConclusionsThis study showed that the %HRmax correlates better with the %VO2max in the late‐stage post‐AMI than in the initial stage. We should therefore set and monitor the exercise intensity using maximal oxygen consumption in the early stage of exercise training after onset of acute myocardial infarction.Level of EvidenceIV
The impact of gas turbine compressor rotor bow on aircraft operations
Authors: Smith E.O. , Neely A.J. , Palfrey-Sneddon H. 
Published: December 2017

ABSTRACTWhen a gas turbine engine is shut down it will develop a circumferential thermal gradient vertically across the compressor due to hot air rising from the cooling metal components and pooling at the top. As the hot compressor rotor drum and casing cool and contract in the presence of this thermal gradient, they do so non-uniformly and therefore will bend slightly, in a phenomenon known as rotor bow. Starting an engine under bowed conditions can result in damage, representing a risk to both airworthiness and operational capability. This study consolidates some preliminary findings by the authors relating to the drivers for rotor bow, such as engine geometry, aircraft-engine integration and rotor temperature on shutdown. The commercial and military operational considerations associated with rotor bow are also discussed, including limitations which may result from a bowed rotor; the influence of operations including the final flight and descent profiles, taxi procedures and rapid turnaround requirements; as well as some practical solutions which may be implemented to reduce the impact of rotor bow.
The mechanics of snow friction as revealed by micro-scale interface observations
Authors: LEVER JAMES H. , TAYLOR SUSAN , SONG ARNOLD J. , COURVILLE ZOE R. , LIEBLAPPEN ROSS , WEALE JASON C. 
Published: December 2017

ABSTRACTThe mechanics of snow friction are central to competitive skiing, safe winter driving and efficient polar sleds. For nearly 80 years, prevailing theory has postulated that self-lubrication accounts for low kinetic friction on snow: dry-contact sliding warms snow grains to the melting point, and further sliding produces meltwater layers that lubricate the interface. We sought to verify that self-lubrication occurs at the grain scale and to quantify the evolution of real contact area to aid modeling. We used high-resolution (15 µm) infrared thermography to observe the warming of stationary snow under a rotating polyethylene slider. Surprisingly, we did not observe melting at contacting snow grains despite low friction values. In some cases, slider shear failed inter-granular bonds and produced widespread snow movement with no persistent contacts to melt (μ < 0.03). When the snow grains did not move and persistent contacts evolved, the slider abraded rather than melted the grains at low resistance (μ < 0.05). Optical microscopy revealed that the abraded particles deposited in air pockets between grains and thereby carried heat away from the interface, a process not included in current models. Overall, our results challenge whether self-lubrication is indeed the dominant mechanism underlying low snow kinetic friction.
A prospective association between dietary folate intake and type 2 diabetes risk among Korean adults aged 40 years or older: the Korean Multi-Rural Communities Cohort (MRCohort) Study
Authors: Hong Sang M. , Woo Hey W. , Kim Mi K. , Kim Se Y. , Lee Young-Hoon , Shin Dong H. , Shin Min-Ho , Chun Byung-Yeol , Choi Bo Y. 
Published: December 2017

AbstractIt has not been well established whether dietary folate intake reduces the risk of diabetes development. We aimed to clarify the prospective association between dietary folate intake and type 2 diabetes (T2D) risk among 7333 Korean adults aged 40 years or older who were included in the Multi-Rural Communities Cohort. Dietary folate intake was estimated from all 106 food items listed on a FFQ, not including folate intake from supplements. Two different measurements of dietary folate intake were used: the baseline consumption and the average consumption from baseline until just before the end of follow-up. The association between folate intake and T2D risk was determined through a modified Poisson regression model with a robust error estimator controlling for potential confounders. For 29 745 person years, 319 cases of diabetes were ascertained. In multivariable analyses, dietary folate intake was inversely associated with risk of T2D for women, not for men. For women, the incidence rate ratio of diabetes in the third tertile compared with the first tertile was 0·57 (95 % CI 0·38–0·87, Pfor trend=0·0085) in the baseline consumption model and 0·64 (95 % CI 0·43–0·95, Pfor trend=0·0244) in the average consumption model. These inverse associations was found in both normal fasting blood glucose group and impaired fasting glucose group among women. Among non-users of multinutrients and vitamin supplements, the significant inverse association remained. Thus, higher dietary intake of folate is prospectively associated with lower risk of diabetes for women.
Neuroanatomical changes in people with high schizotypy: relationship to glutamate levels
Authors: Modinos Gemma , Egerton Alice , McLaughlin Anna , McMullen Katrina , Kumari Veena , Lythgoe David J. , Barker Gareth J. , Aleman André , Williams Steve C. R. 
Published: December 2017

BackgroundCortical glutamatergic dysfunction is thought to be fundamental for psychosis development, and may lead to structural degeneration through excitotoxicity. Glutamate levels have been related to gray matter volume (GMV) alterations in people at ultra-high risk of psychosis, and we previously reported GMV changes in individuals with high schizotypy (HS), which refers to the expression of schizophrenia-like characteristics in healthy people. This study sought to examine whether GMV changes in HS subjects are related to glutamate levels.MethodsWe selected 22 healthy subjects with HS and 23 healthy subjects with low schizotypy (LS) based on their rating on a self-report questionnaire for psychotic-like experiences. Glutamate levels were measured in the bilateral anterior cingulate cortex (ACC) using proton magnetic resonance spectroscopy, and GMV was assessed using voxel-based morphometry.ResultsSubjects with HS showed GMV decreases in the rolandic operculum/superior temporal gyrus (pFWE = 0.045). Significant increases in GMV were also detected in HS, in the precuneus (pFWE = 0.043), thereby replicating our previous finding in a separate cohort, as well as in the ACC (pFWE = 0.041). While the HS and LS groups did not differ in ACC glutamate levels, in HS subjects ACC glutamate was negatively correlated with ACC GMV (pFWE = 0.026). Such association was absent in LS.ConclusionsOur study shows that GMV findings in schizotypy are related to glutamate levels, supporting the hypothesis that glutamatergic function may lead to structural changes associated with the expression of psychotic-like experiences.
An Emendation Proposed for the Text of the ‘Pistola’ of Cerveri de Girona
Authors: Spitzer Leo 
Published: December 2017

I should like to suggest an emendation for line 40 of the poem of Cerveri de Girona that has been so carefully edited by Professor Kurt Lewent in Traditio 6 (1948) 161ff. The line reads in the manuscript: C'a vetz us paucs de mars. The context is as follows (stanza IV) :No us faça trop lau direacuyllimentz ne dosne de non dire aunire.C'a vetzfay tals soletz assirecuy platz asolaçars,mas non an temps de rireo no y tayn messios.Gen chastiatz gardanper que ne com ne qui,c'om non es d'un semblantot l'an ne letz can ri.
The Synodal Letter of Rimini and the Roman Canon Missae
Authors: Michels Dom Thomas 
Published: December 2017

The origin of the actual Roman Canon missae, despite the labors of prominent scholars in the field of Liturgy, remains a secret. We agree with Dom Bernard Botte who declares in regard to questions concerning the Roman Canon:
Il faut reconnaître que jusqu'à present on n'a pas fait la lumière sur des questions très obscures et que les hypothèses les plus ingénieuses ne suffisent pas à satisfaire l'historien quand elles ne reposent pas sur un ensemble de faits bien établis. D'autre part, les hypothèses sont nécessaires à l'avancement de la science et il en est de très séduisantes. Le tout est de ne pas se laisser emporter par elles et de ne pas prendre pour la réalité ce qui n'est que construction provisoire.
Unusually high illness severity and short incubation periods in two foodborne outbreaks ofSalmonellaHeidelberg infections with potential coincidentStaphylococcus aureusintoxication
Authors: NAKAO J. H. , TALKINGTON D. , BOPP C. A. , BESSER J. , SANCHEZ M. L. , GUARISCO J. , DAVIDSON S. L. , WARNER C. , McINTYRE M. G. , GROUP J. P. , COMSTOCK N. , XAVIER K. , PINSENT T. S. , BROWN J. , DOUGLAS J. M. , GOMEZ G. A. , GARRETT N. M. , CARLETON H. A. , TOLAR B. , WISE M. E. 
Published: December 2017

SUMMARYWe describe the investigation of two temporally coincident illness clusters involving salmonella andStaphylococcus aureusin two states. Cases were defined as gastrointestinal illness following two meal events. Investigators interviewed ill persons. Stool, food and environmental samples underwent pathogen testing.Alabama: Eighty cases were identified. Median time from meal to illness was 5·8 h.SalmonellaHeidelberg was identified from 27 of 28 stool specimens tested, and coagulase-positiveS. aureuswas isolated from three of 16 ill persons. Environmental investigation indicated that food handling deficiencies occurred.Colorado: Seven cases were identified. Median time from meal to illness was 4·5 h. Five persons were hospitalised, four of whom were admitted to the intensive care unit.SalmonellaHeidelberg was identified in six of seven stool specimens and coagulase-positiveS. aureusin three of six tested. No single food item was implicated in either outbreak. These two outbreaks were linked to infection withSalmonellaHeidelberg, but additional factors, such as dual aetiology that includedS. aureusor the dose of salmonella ingested may have contributed to the short incubation periods and high illness severity. The outbreaks underscore the importance of measures to prevent foodborne illness through appropriate washing, handling, preparation and storage of food.