bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Choice of Local Food Products by Young Consumers: The Importance of Public and Private Attributes
Authors: Fernández‐Ferrín Pilar , Bande Belén , Calvo‐Turrientes Aitor , Galán‐Ladero M. Mercedes 
Published: May 2016

ABSTRACTIn this paper, we propose an explicative model for the effective purchase of various brands of local products, incorporating private and public motivations into a causal chain and considering product availability as a possible moderator of the effects of these purchase factors on local products. The results obtained by applying conditional process analysis and a Tobit model to the responses of 195 young consumers show that local identity can have direct and/or indirect effects on the effective purchase of four different brands of local, traditional, and nontraditional products. Furthermore, for two of these brands, perceived product availability moderates the relationship between product valuation and effective purchase. [EconLit citations: C51, Q13].
Pectin‐based films produced by electrospraying
Authors: Gaona‐Sánchez Victor A. , Calderón‐Domínguez Georgina , Morales‐Sánchez Eduardo , Chanona‐Pérez J. Jorge , Arzate‐Vázquez Israel , Terrés‐Rojas Eduardo 
Published: May 2016

ABSTRACTElectrospraying technique was used for the production of pectin films obtaining transparent and flexible products with thicknesses of 23.4 ± 3.04 µm and requiring a lower pectin solution volume (2.67 × 10−3 mL) than casting (5.97 × 10−3 mL) to produce films of the same area and thickness; the physical, structural, and thermal characteristics of these films were evaluated. Electrosprayed films were slightly more transparent, and with smoother surface than those obtained by casting, but with more and smaller internal pores, resulting in different film densities (0.7 g/cm3 electrospraying, 1.7 g/cm3 casting), that could be linked to the larger water vapor permeability value obtained. These changes could be related to a physical phenomenon, seeing as the percentage of crystallinity and melting temperature remained invariable for both films. These results show that the electrospraying technique has potential in areas such as wound dressings, tissue engineering, and the release of drugs. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016, 133, 43779.
Four‐Dimensional Screening Anti‐Counterfeiting Pattern by Inkjet Printed Photonic Crystals
Authors: Hou Jue , Zhang Huacheng , Su Bin , Li Mingzhu , Yang Qiang , Jiang Lei , Song Yanlin 
Published: May 2016

AbstractA four‐dimensional screening anti‐counterfeiting QR code composed of differently shaped photonic crystal (PC) dots has been fabricated that could display four images depending on different lighting conditions. By controlling the rheology of poly(dimethylsiloxane) (PDMS), three kinds of PC dots could be sequentially integrated into one pattern using the layer‐by‐layer printing strategy. The information can be encoded and stored in shapes and read out by the difference in optical properties.
Copper, Silver and Sodium Salt‐Mediated Quaternization by Arylation: Syntheses of N‐Heterocyclic Carbene Precursors and 6‐H‐Phenanthridine Derivatives
Authors: Shen Wenqi , Li Jing , Zhang Caiyun , Shi Min , Zhang Jun 
Published: May 2016

AbstractWe have developed a CuII‐, AgI‐, and NaOTf‐mediated intramolecular quaternization by arylation reactions to synthesize a variety of N‐heterocyclic carbene (NHC) precursors with a benzene‐fused backbone. The methodology also provides a convenient alternative route for the synthesis of 6‐H‐phenanthridine derivatives. A novel silver–NHC complex was prepared by treatment of Ag2O with the free carbene, which was in situ prepared from the deprotonation of a representative quinazolinonium salt.
Synthesis and DNA‐binding study of imidazole linked thiazolidinone derivatives
Authors: War Javeed Ahmad , Srivastava Santosh Kumar , Srivastava Savitri Devi 
Published: May 2016

AbstractA novel series of imidazole‐linked thiazolidinone hybrid molecules were designed and synthesized through a feasible synthetic protocol. The molecules were characterized with Fourier transform infrared (FT‐IR), 1H nuclear magnetic resonance (NMR), 13C NMR and high‐resolution mass spectrometry (HRMS) techniques. In vitro susceptibility tests against Gram‐positive (S. aureus and B. subtilis) and Gram‐negative bacteria (E. coli and P. aeruginosa) gave highly promising results. The most active molecule (3e) gave a minimal inhibitory concentration (MIC) value of 3.125 μg/mL which is on par with the reference drug streptomycin. Structure–activity relationships revealed activity enhancement by nitro and chloro groups when they occupied meta position of the arylidene ring in 2‐((3‐(imidazol‐1‐yl)propyl)amino)‐5‐benzylidenethiazolidin‐4‐ones. DNA‐binding study of the most potent molecule 3e with salmon milt DNA (sm‐DNA) under simulated physiological pH was probed with UV–visible absorption, fluorescence quenching, gel electrophoresis and molecular docking techniques. These studies established that compound 3e has a strong affinity towards DNA and binds at DNA minor groove with a binding constant (Kb) 0.18 × 102 L mol−1. Molecular docking simulations predicted strong affinity of 3e towards DNA with a binding affinity (ΔG) ‐8.5 kcal/mol. Van der Waals forces, hydrogen bonding and hydrophobic interactions were predicted as the main forces of interaction. The molecule 3e exhibited specific affinity towards adenine–thiamine base pairs. Copyright © 2016 John Wiley & Sons, Ltd.
An inter‐laboratory cross‐validation study for the determination of perampanel in human plasma by liquid chromatography assays
Authors: Mano Yuji 
Published: May 2016

AbstractFor sample assay to support global clinical studies of perampanel, a novel AMPA receptor antagonist, six chromatographic assay methods in human plasma were developed and fully validated at each laboratory using liquid chromatography with tandem mass spectrometry (LC‐MS/MS) or LC with fluorescence detection (LC‐FL). In this study, samples fortified with known perampanel concentrations were assayed at six laboratories to find whether assay data are comparable. Perampanel was extracted by protein precipitation or liquid–liquid extraction, chromatographed on a reverse‐phase column then detected by MS/MS or FL to achieve the limit of quantification of 0.25 or 1 ng/mL. Cross‐validation samples at four concentrations prepared at a central laboratory were determined at six laboratories and the mean accuracy at each concentration was within ±15% except the low concentration at one laboratory (relative error −17.4%), suggesting that plasma concentrations of perampanel in clinical trials can be compared across laboratories.
Accuracy and procedural characteristics of standard needle compared with radiofrequency needle transseptal puncture for structural heart interventions
Authors: Sharma Gaurav , Singh Gagan D. , Smith Thomas W. , Fan Dali , Low Reginald I. , Rogers Jason H. 
Published: May 2016

ObjectivesOur objectives were to assess for differences between standard and radiofrequency (RF) needle in procedural times, success, and spatial accuracy.BackgroundTargeted transseptal (TS) puncture is essential for structural heart interventions. Spatial accuracy of standard versus RF needle has not been reported.MethodsConsecutive patients undergoing structural heart interventions requiring TS puncture were studied retrospectively. A standard needle was alternated with a RF needle. Procedural success and times were recorded. Measurements based on intraprocedural transesophageal echocardiograms of the intended versus final TS crossing site were obtained. Pre‐puncture and maximal tenting of the septum were also recorded.ResultsTwenty‐five patients underwent standard needle and 27 RF TS access. All RF needle attempts to cross were successful without an assistance wire. Three standard needle patients required assisted crossing. After failed TS access, two patients had successful RF TS access. TS procedural times significantly favored the RF needle for time from septum to puncture (P = 0.02). Both standard and RF access yielded accurate crossing with no significant differences between the intended and actual crossing site. Maximal tenting was significantly less with the RF needle (P = 0.004). There were no major complications.ConclusionsIn the hands of an experienced operator, there were no major clinically significant differences between the standard and RF needle approaches. However, procedural unassisted crossing success was higher with the RF needle approach as compared to standard needle. Procedural times and degree of septum tenting favored the RF over standard needle. Accuracy was similar with both approaches. RF was a successful strategy when standard needle failed. There were no major complications with either TS puncture strategy. © 2016 Wiley Periodicals, Inc.
ChemInform Abstract: Polarization Spectroscopy of SrI in a Heat Pipe: The B2ε+‐X2ε+(0,0) System.
Authors: SCHROEDER J. O. + , NITSCH C. , ERNST W. E. 
Published: May 2016

AbstractSpectra of the B2ε+‐X2ε+(0,0) transition around 674 nm of SrI, produced from the reaction of Sr and NaI in a heat pipe oven, are recorded using Doppler‐free laser polarization spectroscopy.
ChemInform Abstract: Chemical Sources of Singlet Oxygen. Part 3. Peroxidation of Water‐Soluble Singlet Oxygen Carriers with the Hydrogen Peroxide‐Molybdate System.
Authors: AUBRY J. M. , CAZIN B. , DUPRAT F. 
Published: May 2016

AbstractThe β‐naphthalenepropionic acid (I) is oxidized under controlled conditions with singlet oxygen, generated from hydrogen peroxide and sodium molybdate in alkaline solution via a diperoxomolybdate, to form the endo‐peroxide (II).
Tuning the Carbon Dioxide Absorption in Amino Acid Ionic Liquids
Authors: Firaha Dzmitry S. , Kirchner Barbara 
Published: May 2016

AbstractOne of the possible solutions to prevent global climate change is the reduction of CO2 emissions, which is highly desired for the sustainable development of our society. In this work, the chemical absorption of carbon dioxide in amino acid ionic liquids was studied through first‐principles methods. The use of readily accessible and biodegradable amino acids as building blocks for ionic liquids makes them highly promising replacements for the widely applied hazardous aqueous solutions of amines. A detailed insight into the reaction mechanism of the CO2 absorption was obtained through state‐of‐the‐art theoretical methods. This allowed us to determine the reason for the specific CO2 capacities found experimentally. Moreover, we have also conducted a theoretical design of ionic liquids to provide valuable insights into the precise tuning of the energetic and kinetic parameters of the CO2 absorption.
Natural Inhibitors of HMG‐CoA Reductase—An Insilico Approach Through Molecular Docking and Simulation Studies
Authors: Suganya Subramanian , Nandagopal Balaji , Anbarasu Anand 
Published: May 2016

ABSTRACTPlant products have always been considered for many important metabolic disorders due to its abundant medicinal properties. Alarming adverse effects of overuse of statins has been reported for patients with dyslipidemia. This study was aimed to identify compounds with potent anti‐dyslipidemic property from selected plants and analyze them for their efficiency in binding with HMG‐CoA reductase, a key enzyme in lipid metabolism. The docking studies indicate rutin as the best compound that can inhibit HMG‐CoA reductase as it had strong binding affinity to the enzyme. The molecular dynamics simulation studies confirmed the stability of the HMG‐CoA reductase–rutin complex. RMSD, RMSF, Rg, H‐bond results indicated that the HMG‐CoA reductase–rutin complex is highly stable. Presently, statins are not preferred for individuals with pre‐existing liver disease. Our study identified rutin as a promising lead compound which could be further developed into an anti‐dyslipidemic molecule. Our results will be a good starting point for future experimental and clinical studies and if the results from such studies match international standards plant derived rutin might emerge as a good alternative to statins. J. Cell. Biochem. 118: 52–57, 2017. © 2016 Wiley Periodicals, Inc.
A pilot study on the incidence of severe photosensitivity reactions leading to hospitalization linked to topical ketoprofen and other medications in selected European regions
Authors: Cazzaniga Simone , Naldi Luigi , Lecchi Silvia , Kürzinger Marie‐Laure , Auclert Laurent , Gori Mario , Chosidow Olivier , Hercogova Jana 
Published: May 2016

AbstractThe aim of this study was to assess the prevalence of exposure to topical nonsteroidal anti‐inflammatory drugs (NSAIDs), particularly ketoprofen, in a convenience sample of the population, to obtain estimates of the incidence of severe photosensitivity leading to hospitalization, and to assess causative factors in three catchment areas: the Paris metropolitan area, the Lombardy region (Italy) and the Prague area. All cases of severe photosensitivity not explained by underlying conditions and admitted to hospitals in the selected areas were included in the study. Controls were patients consecutively admitted to hospitals, in the same areas, for an acute condition or for an elective procedure not suspected of being related to medication use. From October 2012 to September 2013, 920 controls were recruited (median age 44 years, 50.8% females); 8 severe photosensitivity cases were reported in the population aged 18–74 years of the 3 geographical areas during the 1‐year surveillance period, corresponding to an incidence rate of 4.81 cases per 10 million person‐years (95% confidence interval – CI, 2.07–9.48). Six controls reported 1‐month exposure to topical ketoprofen, with an estimated prevalence of 0.65% (95% CI, 0.24–1.42). The population attributable risk for severe photosensitivity reactions linked to ketoprofen was 11.92% (95% CI, −0.12–52.99). This study was conducted in selected European areas and showed that the incidence of severe photosensitivity reactions leading to hospitalization as well as the exposure rate to topical ketoprofen were low. Among topical NSAIDs, topical ketoprofen was the leading cause of photosensitivity reactions but accounted for a limited number of hospitalized cases. Probably most of the relevant reactions were managed in the outpatient setting and a community based case–control study is advisable.
International Climate Migration: Evidence for the Climate Inhibitor Mechanism and the Agricultural Pathway
Authors: Nawrotzki Raphael J. , Bakhtsiyarava Maryia 
Published: May 2016

AbstractResearch often assumes that, in rural areas of developing countries, adverse climatic conditions increase (climate driver mechanism) rather than reduce (climate inhibitor mechanism) migration, and that the impact of climate on migration is moderated by changes in agricultural productivity (agricultural pathway). Using representative census data in combination with high‐resolution climate data derived from the novel Terra Populus system, we explore the climate–migration relationship in rural Burkina Faso and Senegal. We construct four threshold‐based climate measures to investigate the effect of heatwaves, cold snaps, droughts, and excessive precipitation on the likelihood of household‐level international outmigration. Results from multilevel logit models show that excessive precipitation increases international migration from Senegal while heatwaves decrease international mobility in Burkina Faso, providing evidence for the climate inhibitor mechanism. Consistent with the agricultural pathway, interaction models and results from a geographically weighted regression reveal a conditional effect of droughts on international outmigration from Senegal, which becomes stronger in areas with high levels of groundnut production. Moreover, climate change effects show a clear seasonal pattern, with the strongest effects appearing when heatwaves overlap with the growing season and when excessive precipitation occurs prior to the growing season. Copyright © 2016 John Wiley & Sons, Ltd.
Al‐density variation as one driving force for void formation in PERC solar cells
Authors: Horbelt Renate , Ebert Stefanie , Ulbikaite Vaidvile , Hahn Giso , Job Reinhart , Terheiden Barbara 
Published: May 2016

The reduction of void formation in local Al contact structures is of high interest in studies dealing with passivated emitter and rear contact (PERC) solar cells. So far, several processing parameters and their impact on local contact formation were investigated in detail. However, up to now density variation of Al in dependence on temperature and Si content in the melt were not taken into account as a principal reason for void formation. In this context the current assumption of a constant volume of the Al paste particles is discussed in more detail. Based on the results of energy dispersive X‐ray spectroscopy, void formation implies either an expansion of paste particles or their burst during contact formation.
magnified image (© 2016 WILEY‐VCH Verlag GmbH &Co. KGaA, Weinheim)
A Closed-Form Dynamics of a Novel Fully Wrist Driven by Revolute Motors
Authors: Enferadi J. , Shahi A. 
Published: May 2016

AbstractThis paper proposes a systematic methodology to obtain a closed-form formulation for dynamics analysis of a novel spherical robot that is called a 3(RPSP)-S parallel manipulator. The proposed manipulator provides high rotational displacement of the moving platform for low angular displacement of the motors. The advised robot is suitable for repetitive oscillatory applications (for example, wrist and ankle rehabilitation and table of autopilot and gyroscope life test, etc.). First, we describe the structure of the proposed manipulator and solve the inverse kinematics problem of the manipulator. Next, based on the principle of virtual work, a methodology for deriving the dynamical equations of motion is developed. The elaborated approach shows that the inverse dynamics of the manipulator can be reduced to solving a system of three linear equations in three unknowns. Finally, a computational algorithm to solve the inverse dynamics of the manipulator is advised and several trajectories of the moving platform are simulated and verified by a special dynamics modeling commercial software (MSC ADAMS).
Whole-grain consumption and the risk of all-cause, CVD and cancer mortality: a meta-analysis of prospective cohort studies
Authors: Wei Honglei , Gao Zong , Liang Rui , Li Zengqiang , Hao Hong , Liu Xu 
Published: May 2016

AbstractResults of the relationships between dietary whole-grain consumption and the risk of all-cause, CVD and cancer-specific mortality are mixed. We summarised the evidence based on a meta-analysis of prospective cohort studies. Pertinent studies were identified by searching articles in the MEDLINE and EMBASE databases up to 20 January 2016 and by reviewing the reference lists of the retrieved articles. Random-effects models were used to calculate summary relative risks (SRR) and 95 % CI. In all, eleven prospective studies (ten publications) were included in the meta-analysis. There were a total of 816 599 subjects and 89 251 cases of all-cause mortality. On the basis of the highest v. the lowest categories of intake, whole grains may be associated with a lower risk of mortality from all causes (SRR 0·87; 95 % CI 0·84, 0·90), CVD (SRR 0·81; 95 % CI 0·75, 0·89) and all cancers (SRR 0·89; 95 % CI 0·82, 0·96). For each 3 servings/d increase in whole-grain intake, there was a 19 % reduction in the risk of all-cause mortality (SRR 0·81; 95 % CI 0·76, 0·85), a 26 % reduction in CVD mortality (SRR 0·74; 95 % CI 0·66, 0·83) and a 9 % reduction in cancer mortality (SRR 0·91; 95 % CI 0·84, 0·98). The current meta-analysis provides some evidence that high intake of whole grains was inversely associated with the risk of all-cause, CVD and cancer-specific mortality. Further well-designed studies, including clinical trials and in different populations, are required to confirm our findings.
Molecular cloning and expression of the vitellogenin gene and its correlation with ovarian development in an invasive pest Octodonta nipae on two host plants
Authors: Li Jin-Lei , Tang Bao-Zhen , Hou You-Ming , Xie Yi-Xing 
Published: May 2016

AbstractThere is an ongoing relationship between host plants and herbivores. The nutrient substances and secondary compounds found in the host plant can not only impact the growth and development process of herbivores, but, more importantly, may also affect their survival and reproductive fitness. Vitellogenesis is the core process of reproductive regulation and is generally considered as a reliable indicator for evaluating the degree of ovarian development in females. Vitellogenin (Vg) plays a critical role in the synthesis and secretion of yolk protein. In this study, the full-length cDNA of the Vg gene in an alien invasive species, the nipa palm hispid beetle Octodonta nipae Maulik (Coleoptera: Chrysomelidae) (OnVg) was cloned and, the effect of host plant on the OnVg expression level and ovarian development was investigated. The results revealed that the OnVg was highly and exclusively expressed in adult females, but barely detectable in larvae, pupae and adult males. The relative expression level of OnVg and egg hatchability were much higher in females fed on Phoenix canariensis (their preferred host) than those fed on Phoenix roebelenii. A positive correlation relationship between OnVg expression and egg hatchability was also detected. Additionally, the anatomy of the female reproductive system showed that the ovaries of individuals fed on P. canariensis were considerably more developed than in females fed on P. roebelenii. The results may be applicable to many pest management situations through reproductive disturbance by alternating host plant species or varieties or by reproductive regulation through vitellogenesis mediated by specific endocrine hormones.
Deformations of Fell bundles and twisted graph algebras
Authors: RAEBURN IAIN 
Published: May 2016

AbstractWe consider Fell bundles over discrete groups, and theC*-algebra which is universal for representations of the bundle. We define deformations of Fell bundles, which are new Fell bundles with the same underlying Banach bundle but with the multiplication deformed by a two-cocycle on the group. Every graph algebra can be viewed as theC*-algebra of a Fell bundle, and there are many cocycles of interest with which to deform them. We thus obtain many of the twisted graph algebras of Kumjian, Pask and Sims. We demonstate the utility of our approach to these twisted graph algebras by proving that the deformations associated to different cocycles can be assembled as the fibres of aC*-bundle.
A genome-scale CRISPR-Cas9 screening method for protein stability reveals novel regulators of Cdc25A
Authors: Wu Yuanzhong , Zhou Liwen , Wang Xin , Lu Jinping , Zhang Ruhua , Liang Xiaoting , Wang Li , Deng Wuguo , Zeng Yi-Xin , Huang Haojie , Kang Tiebang 
Published: May 2016

AbstractThe regulation of stability is particularly crucial for unstable proteins in cells. However, a convenient and unbiased method of identifying regulators of protein stability remains to be developed. Recently, a genome-scale CRISPR-Cas9 library has been established as a genetic tool to mediate loss-of-function screening. Here, we developed a protein stability regulators screening assay (Pro-SRSA) by combining the whole-genome CRISPR-Cas9 library with a dual-fluorescence-based protein stability reporter and high-throughput sequencing to screen for regulators of protein stability. Using Cdc25A as an example, Cul4B-DDB1DCAF8 was identified as a new E3 ligase for Cdc25A. Moreover, the acetylation of Cdc25A at lysine 150, which was acetylated by p300/CBP and deacetylated by HDAC3, prevented the ubiquitin-mediated degradation of Cdc25A by the proteasome. This is the first study to report that acetylation, as a novel posttranslational modification, modulates Cdc25A stability, and we suggest that this unbiased CRISPR-Cas9 screening method at the genome scale may be widely used to globally identify regulators of protein stability.