bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Philosophical Approach to Musical Expression: Necessity or Possibility
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractA philosophical approach to musical expression as not necessary but desirable. Pure music as philosophical and instrumental (F. Schlegel). Philosophy and art fulfilling the same mission—to bring a person face to face with the mystery of transcendence (A. Šliogeris). The “secret” and “public” sides of philosophy described by A. Šliogeris: comparison with the inner form and text of music. The philosophical and everyday view of things; Plato’s allegory of the cave; paideia (A. Šliogeris). The concept of beauty as articulated by Aristotle (kalokagathia), St Augustine (unity, proportionality), I. Kant (purposiveness), J. Maritain (brilliance of form). The ability to apply philosophical ideas can deepen an understanding of the subject of music: the ability to hear the voice of the spirit of the being, that is, the creative work (M. Heiddeger), stimulates the possibility of expression. Knowledge works as a tool of power (A. Mickevičius; F. Nietzsche).
The Phenomenological Approach to Musical Expression
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractPhenomenology inquires into the essences inherent in phenomena (M. Heidegger, V. Sesemann). A fact is something which is explained by something else, while a phenomenon is understood from itself. Beauty is born when the essence of the structures of the work is revealed by appropriate means: sounds must fulfil the obligations of the eidos (the artistic idea). E. Husserl envisioned phenomenology as a science of essences or eidetic science (D. Stewart, A. Mickunas): the interpretation of music is the grasping of the essence and its expression. The phenomenon of music expresses aesthetic feelings; this is served by its processual nature: it is close to the dynamics of change in the human emotional condition. The truth is the state in which the being of the phenomenon of transcendence is opened up: musical truth is equal to musical being. Intersubjectivity: the “Other” is the basis for the emergence of the “I” (E. Husserl). Art is dialogue: all music calls to an ear not the musician’s own (M. Buber). The author summarises the principles of the phenomenological approach: (1) the phenomenon of music must be analysed on the basis of eidetics and not according to the habit of the interpreter; (2) the eidetic meaning cannot be detached from the specifics of the work, its musical characteristics, however, a phenomenological action requires reduction, i.e., a narrowing of attention to what is essential; (3) musical reduction happens through a transformation (metanoia) of the thinking of the person-perceiver: a leap from “how it seems to me” to “how it really is”; (4) the art of music exists not only in the space of consciousness, but also in the space of culture; (5) a musical phenomenon opens up what makes it specific and precludes one from explaining it by use of clichés. A work of musical art becomes such exclusively through perception (M. Dufrenne). The Swiss conductor E. Ansermet states that music is “the time that has been experienced” and associates an affective experience with culture: in the realm of culture, the act of transcendence inherent in all musical experience happens by itself.
In Lieu of Conclusions
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractMeaningful expression emerges only when there is an intention—the focusing of the consciousness on the object of interpretation (the work). A work exists insofar as it exists in relation to the person who interprets it (A. Maceina). Music is an art deserving of pity: verses, if they are printed, already live; but a printed composition is still not music: it is necessary to reproduce it, to intone it (B. Asaf’ev). The book highlights the qualities required for the act of interpretation, which is the only path to meaningful expression. Intertextuality: the world is a text and everything has already been said. So, it is only possible to create something new by composing from previously known elements (I. Melnikova): the text is “a new tissue of old quotations” (R. Barthes). The experience stored by the interpreter is enriched by new experiences: interpretive activity is striving for an increasingly effective result. When we see something, we must think something in order to see anything (H. Gadamer): we reach the truth through thinking. It is important to have a soul which loves truth, and receives it wherever it finds it (J. W. von Goethe).
Some Principles of Baroque Aesthetics Which Are Important for Musical Expression
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractOne of the most important prerequisites for the formation of the Baroque style of music was the desire to revive the art of ancient rhetoric, which has the following similarities with music: (1) the sonic nature of the realisation (the perception of the expression through hearing); (2) the processual nature (becoming in a particular segment of time); (3) the emotional nature (the aim of arousing affects); (4) common elements of both languages (verbal and musical): tempo, rhythm, accentuation, articulation, pauses, timbre, intonation and so forth. Mention of R. Descartes’ Compendium of Music and Passions of the Soul as works which exercised a great influence on the theory of affects, and presentation of the ideas of A. Angoulvent on Cartesian philosophy. Application of this to the performance of music, so that the affect is the idea, and its understanding provides the key to the means of expression.According to the Lithuanian musicologist G. Daunoravičienė, intellectual and affective communication between the orator/music and listener characteristic of the Baroque aesthetic means that not only the former (the addresser) but also the latter (the addressee) participates in the becoming of the work. Mention of other principles of Baroque aesthetics in music, such as the ability to think through singing (singend denken), which C. P. E. Bach considered synonymous with playing expressively, and the idea of freedom of movement developed by P. Tosi, which eventually became established in the practice of musical performance as the term rubato (rubare il tempo—“stealing time”; the author connects this with J. J. Quantz’s earlier advice to performers to avoid uniformity when sounding the notes).
Voice and Sound
Authors: Rimas Juozas , Rimas Jr Juozas 
Published: September 2024

AbstractThe principles of rhetoric were transferred from vocal music to instrumental music. Song is an extension of speech, while instrumental music is the transfer of song to an instrument (A. Maceina). Pursuit of song-like instrumental expression (“thinking in terms of song”—C. P. E. Bach) is one of the most important forms of musicality. If the externality of the instrument disappears, in this virtuosity the foreign instrument appears as a perfectly developed organ of the artistic soul (G. Hegel).Discovering a love of singing in his teens, the author developed a vocal orientation. Later, in concert halls, in addition to performing on the oboe, he started to sing Lithuanian folk songs, returning to the singing expression engendered in his childhood. Two pairs of recordings of the author’s performances at various times between 1973 and 2019 are referenced: Grave from the Oboe Concerto in C major by F. Dall’Abaco, and the Lithuanian folk song Vai tu, aglala (“O, you little fir tree”); Largo by the Lithuanian composer J. Indra (1918–1968) and the Lithuanian folk song Rūta žalioj (“Green rue”).Brief discussion of various aspects of vocal quality of sound expression and historical examples: messa di voce, portamento, instrumental obligatos of the arias of cantatas of J. S. Bach, and music of W. A. Mozart for clarinet inspired by A. Stadler. German instrumental culture, which moved in the direction of singende Denken, is illustrated by recordings of three works of W. A. Mozart, performed with the author on oboe—String Quartet No. 12 (KV 172)—Adagio, Three German Dances (KV 605), and German Dance (KV 611). As instrumental music has developed, it has deviated from the principles of ars cantandi.
Angioembolization in patients with blunt splenic trauma in Germany –guidelines vs. Reality a retrospective registry-based cohort study of the TraumaRegister DGU®
Authors: Kölbel Benny , Imach Sebastian , Engelhardt Michael , Wafaisade Arasch , Lefering Rolf , Beltzer Christian ,   TraumaRegister DGU
Published: September 2024

Abstract
Purpose
Nonoperative management (NOM) for blunt splenic injuries (BSIs) is supported by both international and national guidelines in Germany, with high success rates even for severe organ injuries. Angioembolization (ANGIO) has been recommended for stabilizable patients with BSI requiring intervention since the 2016 German National Trauma Guideline. The objectives were to study treatment modalities in the adult BSI population according to different severity parameters including NOM, ANGIO and splenectomy in Germany.

Methods
Between 2015 and 2020, a retrospective registry-based cohort study was performed on patients with BSIs with an Abbreviated Injury Score ≥ 2 in Germany using registry data from the TraumaRegister DGU® (TR DGU). This registry includes patients which were treated in a resuscitation room and spend more than 24-h in an intensive care unit or died in the resuscitation room.

Results
A total of 2,782 patients with BSIs were included in the analysis. ANGIO was used in 28 patients (1.0%). NOM was performed in 57.5% of all patients, predominantly those with less severe organ injuries measured by the American Association for the Surgery of Trauma Organ Injury Scale (AAST) ≤ 2. The splenectomy rate for patients with an AAST ≥ 3 was 58.5%, and the overall mortality associated with BSI was 15%.

Conclusions
In this cohort splenic injuries AAST ≥ 3 were predominantly managed surgically and ANGIO was rarely used to augment NOM. Therefore, clinical reality deviates from guideline recommendations regarding the use of ANGIO and NOM. Local interdisciplinary treatment protocols might close that gap in the future.
Treatment-related leukoencephalopathy in adults with central nervous system lymphoma: a retrospective analysis of 126 patients
Authors: Masuda Yasutaka , Nara Katsuhiko , Fujii-Mori Alice , Shimura Arika , Taoka Kazuki , Watadani Takeyuki , Morita Ken , Yamamoto Takehito , Kurokawa Mineo , Takada Tappei 
Published: September 2024

AbstractNeurotoxicity associated with high-dose chemotherapy and whole brain radiotherapy (WBRT) is one of major complications for patients with central nervous system lymphoma (CNSL). Here we determined the incidence and risk factors of treatment-related leukoencephalopathy (tLE) in a clinical setting. We retrospectively reviewed clinical and radiological findings of 126 patients with (CNSL) treated with high-dose methotrexate with or without intrathecal methotrexate administration (IT MTX) and response-adapted WBRT. During the whole observation period with a median of 38.7 months, tLE was found in 33 patients, most of them asymptomatic, with the median time to development 3.0 months, and the cumulative incidence reaching 29.2% (95% confidence interval, 20.6–38.2%) two years post chemotherapy. By multivariable analysis, IT MTX was identified as the only one significant risk factor (hazard ratio, 4.50; P < 0.001), and the number of IT MTX was associated with the increased incidence and severity of tLE. These findings highlight the frequent neurological complications associated with CNS-directed therapy and confirm the neurotoxicity of IT MTX.
Effects of early-life amino acids supplementation on fish responses to a thermal challenge
Authors: Navarro-Guillén Carmen , Jerez-Cepa Ismael , Lopes André , Mancera Juan Miguel , Engrola Sofia 
Published: September 2024

AbstractNutritional programming is a promising concept for promoting metabolic adaptation of fish to challenging conditions, such as the increase in water temperature. The present work evaluates in ovo arginine or glutamine supplementation as enhancers of zebrafish metabolic or absorptive capacity, respectively, at optimum (28 ºC) and challenging temperatures (32 ºC) in the long-term. Growth performance, free amino acids profile, methylation index and the activity levels of digestive and intermediary metabolism enzymes were analysed to assess the metabolic plasticity induced by an early nutritional intervention. Temperature affected fish larvae growth performance. At the end of the experimental period 28 ºC-fish showed higher dry weight than 32 ºC-fish. The effects of the early supplementation were reflected in the larval free amino acids profile at the end of the experiment. Higher methylation potential was observed in the ARG-fish. In ovo amino acid supplementation modulated the metabolic response in zebrafish larvae, however, the magnitude of this effect differed according to the amino acid and the temperature. Overall, arginine supplementation enhanced carbohydrates metabolism at 32 ºC. In conclusion, the present work suggests that in ovo arginine supplementation may promote a better adaptive response to higher temperatures.
One year follow-up of the colon cancer patient cohort treated with a novel miniaturized robotic-assisted surgery device (mRASD)
Authors: Marks John H. , Jobst Michael A. , Keller Deborah S. , Lagares-Garcia Jorge A. , Schoonyoung Henry P. , Farritor Shane M. , Oleynikov Dmitry 
Published: September 2024

Abstract
Background
With the proven benefits of minimally invasive surgery, there is steady growth in robotic surgery use and interest in novel robotic platforms. A miniaturized Robotic-Assisted Surgery Device (mRASD) has been in clinical use under a multi-center, investigational device exemption (IDE) study for right and left colectomy. The goal of this work was to report the short-term and 12-month outcomes specifically for the cohort of colon cancer patients that underwent surgery using the mRASD.

Method
From the IDE study that included both benign and malignant diseases, long-term follow-up was only conducted for patients with colon cancer. The main outcome measures were the oncologic quality metrics (Overall Survival, OS and Disease-free Survival, DFS). Secondary outcomes included incidence of intra-operative, device-related, and procedure-related adverse events. Frequency statistics were performed to assess the measures of central tendency and variability in short (within 30 days) and long-term (1-year) outcomes.

Results
Thirty total patients underwent a colectomy with mRASD; 17 (57%) were diagnosed with a malignancy and included in this analysis. The mean patient age was 59.9 ± 13.2 years. There were no intraoperative or device-related adverse events. In 100% of cases (n = 17), the primary dissection was completed and hemostasis maintained using the mRASD, and negative margins were achieved. At 30 days postoperatively, the major complication rate was 6%, and there was one unplanned reoperation for anastomotic leak. At one-year follow-up, the OS and DFS rates were 100 and 94%, respectively. In one patient, omental implants were discovered at the time of surgery, and the patient opted to not undergo additional therapy.

Conclusions
The first experience with mRASD for colectomy in colon cancer demonstrated technical effectiveness and an acceptable surgical safety profile in line with other minimally invasive procedures. The study continues to monitor disease recurrence and survival outcomes in this cohort.
Rezidivierende Traumatisierung als Wegbereiter für Komorbiditäten im Bereich dissoziativer und psychosomatischer Störungen
Authors: Aichberger Marion C. , Kocsis-Bogar Krisztina 
Published: September 2024

ZusammenfassungIm Rahmen psychiatrischer und psychotherapeutischer Arbeit ist es nicht selten, dass sich Symptome und die sich davon ableitenden Diagnosen im Behandlungsverlauf ändern. Ein besonderer Stellenwert kommt hierbei den dissoziativen Störungen zu, welche sich oft erst im Verlauf neben anderen Symptomen zeigen können oder auch als einziges Störungsbild vorliegen können. Im Folgenden wollen wir einen Fallbericht einer Patientin mit dem Verdacht auf eine partielle dissoziative Identitätsstörung darstellen.
Community pharmacists’ perceptions and experiences of medicine shortages in disruptive situations: a qualitative study
Authors: Bachoolall Rivana , Suleman Fatima 
Published: September 2024

Abstract

Background
Medicine shortages are a challenge in upper, lower and middle-income countries, including South Africa. In recent years, community pharmacists, in Durban, South Africa, have experienced the COVID-19 pandemic, flooding, civil unrest and electricity disruptions. Little is known about the impact of these disruptions on medicine shortages in community pharmacies.

Aim
To explore community pharmacists' perceptions and their experiences with medicine shortages during the COVID-19 pandemic and other disruptive situations.

Method
Convenience and snowball sampling were used to recruit participants. Semi-structured interviews were conducted in person or via an online video conferencing platform, which were audio-recorded and transcribed verbatim. Using the Framework Method, the transcripts were analysed thematically on NVivo 14 software.

Results
Fifteen community pharmacists were interviewed. Five major themes emerged from thematic analysis: general perceptions of medicine shortages, the impact of disruptive situations, the consequences of medicine shortages, mitigation strategies; and further suggestions and resources. Disruptive situations were perceived to exacerbate shortages. Participants perceived a negative financial impact on patients and pharmacies, with out-of-pocket costs affecting the former and loss of income affecting the latter. The mitigation strategies used were contacting stakeholders, medicine substitution and stock management.

Conclusion
Community pharmacists felt that improved communication, collaboration, policies, notification systems and guidelines would mitigate shortages.
A stacking-based model for the spread of Botryosphaeria laricina
Authors: Zhou Hongwei , Zhang Shibo , Xie Meng , Li Xiaodong , Chen Yifan , Dai Wenhao 
Published: September 2024

AbstractBotryosphaeria laricina (larch shoot blight) was first identified in 1973 in Jilin Province, China. The disease spread rapidly and caused considerable damage because its pathogenesis was unknown at the time and there were no effective controls or quarantine methods. At present, it shows a spreading trend, but most research can only conduct physiological analyses within a relatively short period, combining individual influencing factors. Nevertheless, methods such as neural network models, ensemble learning algorithms, and Markov models are used in pest and disease prediction and forecasting. However, there may be fitting issues or inherent limitations associated with these methods. This study obtained B. laricina data at the county level from 2003 to 2021. The dataset was augmented using the SMOTE algorithm, and then algorithms such as XGBoost were used to select the significant features from a combined set of 12 features. A new stacking fusion model has been proposed to predict the status of B. laricina. The model is based on random forest, gradient boosted decision tree, CatBoost and logistic regression algorithms. The accuracy, recall, specificity, precision, F1 value and AUC of the model reached 90.9%, 91.6%, 90.4%, 88.8%, 90.2% and 96.2%. The results provide evidence of the strong performance and stability of the model. B. laricina is mainly found in the northeast and this study indicates that it is spreading northwest. Reasonable means should be used promptly to prevent further damage and spread.
Comparative Effects of Tumor Necrosis Factor Alpha, Lipopolysaccharide, and Palmitate on Mitochondrial Dysfunction in Cultured 3T3-L1 Adipocytes
Authors: Jack Babalwa Unice , Dias Stephanie , Pheiffer Carmen 
Published: September 2024

Abstract
We have previously reported that dysregulated lipid metabolism and inflammation in 3T3-L1 adipocytes is attributed to tumor necrosis factor alpha (TNFα) rather than lipopolysaccharide (LPS) and palmitate (PA). In this study, we further compared the modulative effects of TNFα, LPS, and PA on mitochondrial function by treating 3T3-L1 adipocytes with TNFα (10 ng/mL), LPS (100 ng/mL), and PA (0.75 mM) individually or in combination for 24 h. Results showed a significant reduction in intracellular adenosine triphosphate (ATP) content, mitochondrial bioenergetics, total antioxidant capacity, and the mRNA expression of citrate synthase (Cs), sirtuin 3 (Sirt3), protein kinase AMP-activated catalytic subunit alpha 2 (Prkaa2), peroxisome proliferator-activated receptor gamma coactivator 1 alpha (Ppargc1α), nuclear respiratory factor 1 (Nrf1), and superoxide dismutase 1 (Sod1) in cells treated with TNFα individually or in combination with LPS and PA. Additionally, TNFα treatments decreased insulin receptor substrate 1 (Irs1), insulin receptor substrate 2 (Irs2), solute carrier family 2, facilitated glucose transporter member 4 (Slc2a4), and phosphoinositide 3 kinase regulatory subunit 1 (Pik3r1) mRNA expression. Treatment with LPS and PA alone, or in combination, did not affect the assessed metabolic parameters, while the combination of LPS and PA increased lipid peroxidation. These results show that TNFα but not LPS and PA dysregulate mitochondrial function, thus inducing oxidative stress and impaired insulin signaling in 3T3-L1 adipocytes. This suggests that TNFα treatment can be used as a basic in vitro model for studying the pathophysiology of mitochondrial dysfunction and related metabolic complications and screening potential anti-obesity therapeutics in 3T3-L1 adipocytes.
Understanding the Impacts of Child Sexual Abuse in China from a Cultural Perspective: An Analysis of Posts from an Online Q&A Forum
Authors: Tao Yingxue 
Published: September 2024

AbstractDespite the awareness of the necessity to look from a cultural perspective, few studies have examined how cultural factors influence psychological change after child sexual abuse (CSA) in the Chinese population. This study examined 830 posts on a Chinese online Q&A forum and used thematic analysis to extract important themes and reveal the impacts of child sexual abuse and discuss related cultural values. Three main themes were identified: Forces Making CSA Unspeakable, Long-term Impacts of CSA, and Disillusionment with the Full Recovery. This study suggested that CSA can lead to Dilemmas in Interpersonal Relationships, Self-alienation, Beliefs in Irreparableness of the Damage, and Limited Coping Methods. It also explored how cultural factors such as Sexual Objectification of Women, Patriarchy and Familism, and Minimalization of Non-penetrative Abuse exacerbate these challenges. The contribution of this study is its thorough analysis of the impact of CSA within the context of Chinese culture, along with its novel insights into the role of online posting in the psychological recovery of survivors. Professionals should consider the cultural backgrounds of survivors’ distress, coping, and recovery-related beliefs to develop models of culturally responsive care for survivors.