bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the Possibility of Detecting Brucella Canis from Tissue Samples Using Bruce-Ladder Multiplex PCR Assay
Authors: Stević Nataša , Mišić Dušan , Bogunović Danica , Matović Kazimir , Valčić Miroslav , Milovanović Milovan , Radojičić Sonja 
Published: January 2018

Abstract
The goal of this study was to compare the results of serological and conventional bacteriological methods with the results obtained using multiplex PCR Bruce-ladder assay. Based on the obtained results, the usability of the assay was assessed in regard to rapid diagnosis of canine brucellosis directly from the samples of reproductive organs of infected dogs. Out of 225 blood samples, 33 (14.67%) had a positive agglutination reaction. In this study, out of the 225 assayed reproductive organs of dogs, B. canis was isolated from 3 samples (1.33%), while the PCR Bruce-ladder assay detected two positive samples (0.88%). Two dogs from which B. canis was isolated, an antibody titer of 1/200 was established in blood serums, and third dog from which B. canis was isolated was negative using the tube agglutination test. From a total of 225 assayed organ samples, a positive PCR reaction was obtained from two samples. The obtained results show that the tube agglutination method remains the first choice for the detection of dogs infected with B. canis. In addition, whenever possible, it is necessary to try isolation. It is desirable to attempt the detection of B. canis in tissues using PCR, but the results may not be treated as definitive and reliable.
Entwurf robuster optischer Systeme am Beispiel des Künstlichen Akkommodationssystems
Authors: Sieber Ingo 
Published: January 2018

Zusammenfassung
Der modulare Aufbau optischer Systeme bedingt eine isolierte Herstellung der einzelnen Komponenten und ihres
nachgeordneten Zusammenbaus zu einem Gesamtsystem. Sowohl die Herstellung als auch das Zusammenfügen der einzelnen
Komponenten unterliegen Toleranzen. Materialverzüge, verursacht durch umgebungs- und betriebsbedingte
Effekte, führen zu Fehlpositionierungen und damit zu eingeschränkter Funktionstüchtigkeit. Um die
Fertigbarkeit bereits in der Modellbildung sicherzustellen, müssen Entwurfsregeln eingebunden werden. In diesem Artikel
wird eine Vorgehensweise vorgestellt, welche unter Berücksichtigung von Fertigungsregeln und -toleranzen und
Umgebungseinflüssen die Entwurfsauslegung eines robusten und fertigungsgerechten optischen Systems sicherstellt. Die
Vorgehensweise findet Anwendung auf das aktiv-optische System des Künstlichen Akkommodationssystems.
Dämpfung von Leistungspendelungen in Energienetzen – Stand der Technik
Authors: Wohlfarth Herbert 
Published: January 2018

Zusammenfassung
Power System Stabilizer (PSS) und netzseitig regelbare Betriebsmittel spielen weltweit eine zentrale Rolle für die
dynamische Stabilität von Energieversorgungsnetzen. Der Beitrag beschreibt die Entwicklung gängiger Verfahren zur Dämpfung
von Leistungspendelungen, die wesentlichen Erkenntnisse zum Reglerdesign, zu Wechselwirkungen zwischen den
beteiligten Komponenten und zu Optimierungsansätzen sowie den Stand der
Implementierungspraxis. Darüber hinaus werden besondere Anforderungen an Wide Area Measurement Systems
vorgestellt. Auch wird die aktuelle Methodenvielfalt und daraus resultierend die Notwendigkeit einer standardisierten
Vergleichbarkeit innovativer Konzepte verdeutlicht.
Fault-tolerant tracking control of petri nets
Authors: Fritz Raphael , Zhang Ping 
Published: January 2018

Abstract
In this paper, the fault-tolerant tracking control of petri nets is considered. The control aim is to steer a petri net
in case of faults from an initial marking into a destination marking by an appropriate firing sequence. Sensor, actuator
and process faults in the plant are modeled based on four types of faulty transitions. Depending on the characteristics of
the faults, two approaches are proposed to handle the faults. The tracking control problem is realized by solving two
integer linear programming problems. This two-step approach reduces the computational effort significantly. Faults are
taken into account as constraints and by adapting the firing sequence. Finally, an example is given to illustrate the
proposed fault-tolerant tracking control approach.
Instability detection of the tire-road contact and torque control for wheel-individual driven vehicles
Authors: Speth Peter , Hummler Andreas , Buchholz Michael , Dietmayer Klaus 
Published: January 2018

Abstract
Traction control for vehicles with wheel individual drives is a challenging task, since the wheel slips are unknown when
each wheel transfers a torque. This contribution presents an approach which deals with this problem especially for
electrical vehicles, where the drive torques can be changed very fast in comparison to vehicles with combustion
engines. The algorithm is based on two filters. The first filter is an adaptive Kalman filter which is used to detect fast
changes in the stability conditions of the wheels. The filter also delivers a valuation for the torque to which the drive
torque has to be reduced to get the wheel stable again. The second filter estimates the wheel slip. It is based on
a simplified expression of the slip dynamics in combination with a special reset strategy for low slip situations. This
filter allows detection of slow changes in the stability conditions. All filters are wheel individual and use only
standard sensor information. No tire model is needed for the filters to work. A simple reflexive traction controller,
which is based on a state machine, computes the drive torques in dependence on the stability criteria based on the filter
outputs.
Environmental and nutritional requirements for tea cultivation
Authors: Hajiboland Roghieh 
Published: January 2018

Abstract
Tea (Camellia sinensis) is an important beverage crop cultivated in the tropics and subtropics under acid soil conditions. Increased awareness of the health-promoting properties of the tea beverage has led to an increase in its level of consumption over the last decades. Tea production contributes significantly to the economy of several tea-cultivating countries in Asia and Africa. Environmental constrains, particularly water deficiency due to inadequate and/or poorly distributed rainfall, seriously limit tea production in the majority of tea-producing countries. It is also predicted that global climate change will have a considerable adverse impact on tea production in the near future. Application of fertilizers for higher production and increased quality and quantity of tea is a common agricultural practice, but due to its environmental consequences, such as groundwater pollution, the rate of fertilizer application needs to be reconsidered. Cultivation of tea under humid conditions renders it highly susceptible to pathogens and pest attacks. Application of pesticides and fungicides adversely affects the quality of tea and increases health risks of the tea beverage. Organic cultivation as an agricultural practice without using synthetic fertilizers and other chemical additives such as pesticides and fungicides is a sustainable and eco-friendly approach to producing healthy tea. A growing number of tea-producing countries are joining organic tea cultivation programmes in order to improve the quality and to maintain the health benefits of the tea produced.
Homotopy Continuation Method to Evaluate Catalytic Rates for Highly Exothermic Reaction Systems
Authors: Tiscareño-Lechuga Fernando 
Published: January 2018

AbstractCalculation of simultaneous catalytic reaction rates represents a system of nonlinear differential equations with two boundaries; additionally, nonlinear algebraic equations are added if external mass and energy resistances are significant. For highly exothermic reactions and some reaction networks, numerical solution with typical shooting methods encounters difficulties to find good initial guesses since the equation system becomes very rigid. A Numerical Homotopy Continuation approach is proposed in which the particle size is progressively increased until the specified dimensions; shooting variables corresponding at the center of the particle are used as nearby solutions which allows to trace and update the initial guesses.
Actions related to International Bureau for Epilepsy during my term as President 2013–2017
Authors: Covanis Athanasios 
Published: January 2018

Summary
The International Bureau for Epilepsy (IBE) Executive Committee for the term 2013–2017 began in June 2013 during the 30th International Epilepsy Congress in Montreal. From the beginning, our primary goals were to fulfil the mission of our organisation and address problems such as awareness, education, and social issues, while promoting and protecting the human rights of persons with epilepsy (PWE) and improving trans-regional equity in access to health care services, improved prevention, diagnosis and treatment and as a consequence, a reduction in the treatment gap and alleviation of stigma worldwide. By so doing, the quality of life of PWE and those who care of them will be significantly improved. In order to achieve these aims, the IBE joined forces with the International League Against Epilepsy (ILAE) and also the World Health Organisation (WHO), regional and national IBE organisations and other stakeholders.
In addition, the participation of the IBE President in many national epilepsy events worldwide has helped to promote care and human rights of PWE nationally. A major awareness event accomplished during our term in office was the launch of the International Epilepsy Day in 2015. An IBE-ILAE event celebrated the 2nd Monday in February each year at the European Parliament with the participation of many stakeholders, PWE and advocates for epilepsy MEPs.
In 2014 in order to improve access to care, treatment, appropriate treatment for PWE worldwide, particularly in developing countries, we developed our strategy plan becoming IBE’s roadmap up to 2019 and with strategic priorities to establish epilepsy as a health priority worldwide. In June 2014, in Troina, Italy, WHO, ILAE, IBE and the Global Outreach Research Task Force organised a workshop to discuss how to improve access to antiepileptic medicines in low- and middle-income countries and, as a consequence, to produce a white paper. A unique historical achievement during our term in office was the approval from WHO and subsequently from World Health Assembly (WHA) (May 26th, 2015) the Resolution on the Burden of epilepsy, and calls on United Nation Member States to implement the WHA68.20 actions and for WHO to report back in 2018. The creation by IBE/ILAE in 2016 the legal entity Epilepsy Alliance Europe has given the opportunity for both organizations to play a partnership role in many research projects aiming to reduce the epilepsy burden in Europe and worldwide.
Improved medical-alert ID ownership and utilization in youth with congenital adrenal hyperplasia following a parent educational intervention
Authors: Vidmar Alaina P. , Weber Jonathan F. , Monzavi Roshanak , Koppin Christina M. , Kim Mimi S. 
Published: January 2018

Abstract

Background:
Classical congenital adrenal hyperplasia (CAH) is a potentially life-threatening condition, and adrenal crisis is a major cause of morbidity and mortality in affected children. Medical-alert identification (ID) could prevent complications of adrenal crisis by identifying the need for time-sensitive, critical treatment. Our objectives were to evaluate usage of medical-alert IDs by CAH youth, ownership and awareness of IDs amongst their parents, and the effect of an in-clinic educational intervention on ID utilization.

Methods:
Fifty families of youth with classical CAH secondary to 21-hydroxylase deficiency (11.2±5.0 years old, 58% female) were prospectively studied. An in-clinic needs assessment survey was administered at baseline to parents, paired with an educational intervention, and a follow-up needs assessment phone survey 1 month post-intervention. A quality improvement (QI) framework was utilized with plan-do-study-act (PDSA) process-improvement cycles.

Results:
At baseline, 20/50 (40%) CAH families owned a medical-alert ID, of which only 10/20 (50%) of ID owners reported usage >3 days per week. Only 26/50 (52%) parents were aware of ID options. Post-intervention, ID ownership doubled to 39/50 (78%; p<0.05), usage amongst ID owners reached 100% (39/39), and awareness increased to 42/50 (84%; p<0.05). A surprising barrier reported by five Spanish-speaking families was the inability to order medical-alert IDs online.

Conclusions:
Only a small percentage of CAH youth frequently wear a medical-alert ID, but utilization can be effectively improved with an in-clinic educational intervention. Further study is merited to assess a potential reduction in morbidity and mortality of adrenal crisis with increased medical-alert ID utilization.
Dynamic Testing of Buses and their Components
Authors: Záruba Petr , Jelínek Jakub , Kalinský Michal 
Published: January 2018

Abstract
The article gives an overview of a virtual simulation method under ECE Regulation No. R66 - bus rollover. The first part of the article introduces the process of virtual simulations in terms of homologation. The conclusion is focused on the correlation of physical tests with virtual simulations.
Ideas for Testing of Planetary Gear Sets of Automotive Transmissions
Authors: Achtenová Gabriela 
Published: January 2018

Abstract
The article describes the concept of modular stand, where is possible to provide tests of gear pairs with fixed axes from mechanical automotive gearboxes, as well as tests of separate planetary sets from automatic gearboxes. Special attention in the article will be paid to the variant dedicated for testing of planetary gear sets. This variant is particularly interesting because: 1) it is rarely described in the literature, and 2) this topology allows big simplification with respect to testing of standard gearwheels. In the planetary closed-loop stand it is possible to directly link two identical planetary sets. Without any bracing flange or other connecting clutches, shafts or gear sets, just two planetary sets face-to-face will be assembled and connected to the electric motor.
Experience in design and construction of the Log tunnel
Authors: Jovičić Vojkan , Goleš Niko , Tori Matija , Peternel Miha , Vajović Stanojle , Muhić Elvir 
Published: January 2018

Abstract
A twin highway Log tunnel is a part of a new motorway connection between Maribor and Zagreb, section Draženci-Gruškovje, which is located towards the border crossing between Slovenia and Croatia. The tunnel is currently under construction, and only the excavation works have been completed during the writing of this paper. The terrain in the area of the Log tunnel is diverse, and the route of the highway in its vicinity is characterised by deep excavations, bridges or viaducts. The Log tunnel is approximately 250 m long, partly constructed as a gallery. The geological conditions are dominated by Miocene base rock, featuring layers of well-connected clastic rocks, which are covered by diluvium clays, silts, sands and gravels of different thicknesses. Due to the short length of the tunnel, the usual separation of the motorway route to the left and the right tunnel axes was not carried out. Thus, the tunnel was constructed with an intermediate pillar and was designed as a three-lane tunnel, including the stopping lane. The construction of the tunnel was carried out using the New Austrian tunnelling method (NATM), in which the central adit was excavated first and the intermediate pillar was constructed within it. The excavation of the main tubes followed and was divided into the top heading, bench and the invert, enabling the intermediate pillar to take the load off the top heading of both tubes. The secondary lining of the tunnel is currently under construction. The experience of the tunnel construction gathered so far is presented in the paper. The main emphasis is on the construction of the intermediate pillar, which had to take the significant and asymmetrical ground load.
Application of PRINCE2 Project Management Methodology
Authors: Vaníčková Radka 
Published: January 2018

Abstract
The methodology describes the principle of setting a project in PRINCE2 project management. The main aim of the paper is to implement PRINCE2 methodology to be used in an enterprise in the service industry. A partial aim is to choose a supplier of the project among new travel guides. The result of the project activity is a sight-seeing tour/service more attractive for customers in the tourism industry and a possible choice of new job opportunities. The added value of the article is the description of applying the principles, processes and topics of PRINCE2 project management so that they might be used in the field.
Infancia, vivienda y ciudad. Una mirada en el contexto de Bogotá, Colombia
Authors: Ceballos Ramos Olga Lucía 
Published: January 2018

El concepto de infancia ha tomado fuerza desde la promulgación de los derechos del niño, a partir de lo cual los infantes pasaron de ser considerados objeto de tutela del Estado a ser sujetos de derechos. En Colombia, la Constitución Política de 1991, en su artículo 44, además de reconocer los derechos de los niños les da el estatus de prevalencia sobre los demás. Transcurridas ya dos décadas, y aún desde antes, son numerosas las políticas y acciones en general promovidas en el país para el debido cumplimiento de este precepto constitucional. Bogotá, dada su condición de capital política y económica del país, se ha convertido en la principal receptora de las migraciones asociadas al desplazamiento producto del conflicto armado interno. A su vez, este proceso migratorio ha estado fuertemente asociado con la aparición de asentamientos informales en donde las acciones para la atención de la infancia denotan desencuentros con el hábitat. ¿Qué ha sucedido con los niños y las niñasque habitan allí? ¿Inciden las condiciones de su hábitat en el acceso efectivo a sus derechos? ¿Qué se hace desde el planeamiento territorial y las políticas de vivienda para garantizar los derechos de la infancia? Esa es la reflexión que se propone en el presente artículo.
Construyendo la imagen de una ciudad segura: la disminución de la violencia visible en Río de Janeiro
Authors: Saborío Sebastían 
Published: January 2018

Desde el 2008 en Río de Janeiro se ha puesto en práctica una nueva política de seguridad pública: la pacificación de las favelas. Esta consiste en la tomada de control, por parte de las Unidades de Policía Pacificadora (UPPs), de algunas de las favelas ocupadas por grupos criminales fuertemente armados. El presente artículo demuestra que, contrariamente a lo que afirman las instituciones locales, la pacificación de las favelas no tiene como objetivo principal “llevar la paz” dentro de territorios urbanos caracterizados por altos índices de violencia. Aquí se sostiene que las UPPs hacen parte de una estrategia más amplia de reducción de la visibilidad de la violencia y, enconsecuencia, de la fama de Río de Janeiro de ser una ciudad peligrosa.
Sign Code Development Process: Best Practices
Authors: Jourdan Dawn , Strauss Eric , Hunter Madeline 
Published: January 2018

A wide variety of community stakeholders have an interest in ensuring that sign codes are crafted in such a way as to allow for the free flow of speech while preserving community character. These stakeholders may include businesses, sign companies, graphic designers, historic preservationists, traffic safety specialists, environmental quality advocates, and chamber of commerce types, among others. Including interested parties in efforts to develop and revise sign codes can help ensure that the resulting regulation embraces the best available technologies and business practices of the time in an effort to promote the economic vitality of local business districts. This report seeks to: (a) explore best practices in citizen participation practices revolving around the development or amendment of sign codes; (b) to evaluate the experiences of communities who have revised their sign codes in the last 10 years; and (c) to establish best practices for improving the sign code development process.
Validation and Refinement of the Age, Comorbidities, and Albumin Index in Elderly Patients with Diffuse Large B-Cell Lymphoma: An Effective Tool for Comprehensive Geriatric Assessment
Authors: Liu Hui , Zhang Chun-Li , Feng Ru , Li Jiang-Tao , Tian Yuan , Wang Ting 
Published: January 2018

Abstract

Background
We aimed to validate and refine the Age, Comorbidities, and Albumin (ACA) index in elderly Chinese patients with diffuse large B-cell lymphoma (DLBCL) and propose a more effective method for comprehensive geriatric assessment (CGA).

Materials and Methods
Patients ≥65 years of age who had been diagnosed with de novo DLBCL in the Institute of Hematology, Beijing Hospital, were screened for eligibility (n = 99).

Results
Based on the ACA index, 39, 31, 26, and 3 patients were categorized into the “excellent,” “good,” “moderate,” and “poor” groups, respectively. The 2-year treatment-related mortality rate was significantly higher and the survival rates poorer in the ACA “moderate to poor” group compared with those of the ACA “good” and “excellent” groups. Multivariable model analysis identified two independent predictors of overall survival: the instrumental activities of daily living (IADL) scale and the ACA index. IADL scores of 6 to 7 and the ACA “good” group were assigned 1 point; IADL scores ≤5 and the ACA “moderate to poor” group were assigned 2 points. Based on these data, we created a three-category system (IADL ACA index [IACA index]): low risk, score 0; intermediate risk, score 1 to 2; and high risk, score 3 to 4. The IACA index could effectively discriminate the response rates, overall survival, and progression-free survival rates in elderly patients with DLBCL.

Conclusion
We observed that the ACA index could partially predict the clinical outcomes of elderly DLBCL patients in China. Based on this index, we proposed the IACA index as an effective tool for CGA in DLBCL.

Implications for Practice
Diffuse large B-cell lymphoma (DLBCL) is one of the most frequent types of malignant lymphoma in elderly people, and identifying patients suitable for curative therapy is critical in the improvement of clinical outcomes. Recently, some authors proposed the Age, Comorbidities, and Albumin (ACA) index. Combining the use of the instrumental activities of daily living (IADL) scale and the ACA index, this article describes the IADL ACA index (IACA index), which is an effective tool for comprehensive geriatric assessment in DLBCL.
El primer panamericanismo: puente entre el derecho de gentes y el derecho internacional
Authors: Castaño Luis Ociel 
Published: January 2018

This essay provides a comprehensive and analytical look, devoid of traditional patriotic emotion which often accompanies the study of the initial page of the political annals of The Americas, one that is never finished, always under construction, and permanently relevant, as it relates to the attempt at the political (re)integration of Latin America. It deals with a specific juncture where the newly acquired independence of the territorial entities recently liberated from Spain was being timidly consolidated, as they entered the international arena, more than by force of arms by the circumstances of the moment, which precluded a turbulent and contradictory Spain from successfully reconquering much of its old overseas territories, as she was immersed in the assimilation of liberalism and ius political modernity at home. It explains the background, details and reasons for the initial failure of the region´s political integration during the first three decades of the nineteenth century. It seeks to contribute to the dissemination of the history of Latin American law and political institutions.