bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-Term Histopathology of Intracranial Aneurysms after Endovascular Treatment with Coils
Authors: Suda Y. , Kikuchi K. , Shioya H. , Shindo K. , Nanjo H. , Masuda H. 
Published: January 2017

We describe the results of electron microscopic examination in two patients with ruptured intracranial aneurysms who were successfully treated by endovascular coil embolization. The aneurysms were seen completely occluded on the follow-up angiograms. Autopsies of these patients were performed five and 26 months after endovascular treatment when they died of pneumonia and thalamic hemorrhage, respectively. The aneurysms were densely filled with the coils, which were readily identified through the thin and transparent wall of the aneurysmal dome. The orifice of the aneurysm was completely occluded so that macroscopically the coils were not directly visualized through the orifice. To examine any evidence of endothelialization across the orifice of the aneurysms, scanning electron microscopic examination was performed. In both cases, evidence of well regenerative endothelialization was observed across the aneurysmal orifice, being contiguous with the endothelial layer of the adjacent parent vessels. These ultrastructural findings indicate that the aneurysms are completely isolated from the lumen of the parent artery by a continuous lining of the regenerated endothelial cells following the endovascular treatment with coils, and further suggest that aneurysms have a potential of being cured permanently by this treatment modality. This is, to the best of our knowledge, the first report in humans verifying a complete endothelialization of the luminal surface at the aneurysmal neck after coil embolization, as evidenced by scanning electron microscopy.
Endothelial Dysfunction in Rheumatoid Arthritis is Improved by Anti-Tumor Necrosis Factorα Treatment
Authors: Capria A. , De Nardo D. , De Sanctis G. , Simonelli A.R. , Kroegler B. , Silvestri F. , Franconi G. , Fontana L. 
Published: January 2017

Rheumatoid arthritis (RA) is associated with excess cardiovascular morbidity and mortality. TNFα plays a pivotal role in causing both RA synovial damage and atherosclerosis, also by inducing endothelial dysfunction. The aim of the present study was to assess the occurrence of endothelial dysfunction and the effects of anti-TNFα antagonism on endothelial function in RA. Ten RA women with Disease Activity Score (DAS) ≥ 3.7 despite treatment with at least two disease-modifying antirheumatic drugs for 4 months underwent anti-TNFα treatment with infliximab or etanercept. Endothelium-dependent vasodilation was significantly lower than normal (3.8±3.7 % vs. 13.7 ±5.1, p≤0.05), thus demonstrating the presence of endothelial dysfunction in our RA patient population. Anti-TNF- treatment significantly improved flow-mediated vasodilation, which increased from baseline values of 3.8±3.7% to 10.9±6.6% (p<0.05) at day 1, to 13.4±5.4 % (p < 0.05) at week 1, to 12.7±5.3 % (p<0.05) at week 2 and to 15.5±5.2 % at week 6 (p≤0.05). There was no significant difference between two anti-TNFα treatments regarding mean percentage increase of flow-mediated vasodilation during treatment. RA clinical improvement was demonstrated by a significant decrease in the DAS score (from 6.26±1.6 to 5.26 1.38, p < 0.05) associated to a marked decrease of acute phase reactants serum levels. The present study supports the hypothesis of the pivotal role for TNFα as a mediator of systemic and vascular wall inflammation in RA.
Evidence-Based Design Features Improve Sleep Quality Among Psychiatric Inpatients
Authors: Pyrke Ryan J. L. , McKinnon Margaret C. , McNeely Heather E. , Ahern Catherine , Langstaff Karen L. , Bieling Peter J. 
Published: January 2017

Objective: The primary aim of the present study was to compare sleep characteristics pre- and post-move into a state-of-the-art mental health facility, which offered private sleeping quarters. Background: Significant evidence points toward sleep disruption among psychiatric inpatients. It is unclear, however, how environmental factors (e.g., dorm-style rooms) impact sleep quality in this population. Methods: To assess sleep quality, a novel objective technology, actigraphy, was used before and after a facility move. Subjective daily interviews were also administered, along with the Horne–Ostberg Morningness–Eveningness Questionnaire and the Pittsburgh Sleep Quality Index. Results: Actigraphy revealed significant improvements in objective sleep quality following the facility move. Interestingly, subjective report of sleep quality did not correlate with the objective measures. Circadian sleep type appeared to play a role in influencing subjective attitudes toward sleep quality. Conclusions: Built environment has a significant effect on the sleep quality of psychiatric inpatients. Given well-documented disruptions in sleep quality present among psychiatric patients undergoing hospitalization, design elements like single patient bedrooms are highly desirable.
The efficacy of a shared-care surveillance protocol for asymptomatic renal calculi
Authors: Ravindra P , Voss J , Hall S , Stanford RJ , Scriven SD , Ratan HL 
Published: January 2017

Objective: Patients at our institution with asymptomatic calyceal stones (<11 mm) are discharged to their GPs with a request for 12- and 24-month X-ray KUBs with specific re-referral criteria. We aimed to assess the effectiveness of this shared care protocol as well as to investigate long-term outcomes. Patients and methods: All patients satisfying the above criteria discharged during October 2009–June 2011 were reviewed for protocol compliance, symptomatic events and/or surgical intervention up to July 2015. Results: A total of 134 patients were identified. Out of 115 patients eligible for their first X-ray, and 100 patients eligible for their second X-ray, 43% and 26% respectively were performed. Of these, 75% demonstrated no progression. No patients were treated surgically solely on the basis of radiographic progression. Over a mean five-year follow-up, patients had a 39% chance of experiencing a symptomatic event and a 24% chance of requiring surgical intervention (ESWL, ureteroscopy and/or PCNL). Risk factors included a previous stone history and having a total stone size >10 mm. Conclusion: There was poor adherence to this protocol. Despite this, only symptomatic patients were treated surgically, challenging the value of indefinite surveillance of asymptomatic patients. Longitudinal studies are needed to determine a cost-effective manner in which these patients can be safely followed up.
Training in Integrative Therapies Increases Self-Efficacy in Providing Nondrug Therapies and Self-Confidence in Offering Compassionate Care
Authors: Kemper Kathi J. , Hill Ellie 
Published: January 2017

Background. Patient demand and clinician interest have driven professional training in integrative therapies, but few rigorous evaluations have been published. Methods. This project evaluated the proof of concept of training in acupressure, guided imagery, massage, and Reiki on clinicians’ sense of self-efficacy in providing nondrug therapies, self-confidence in providing compassionate care, and engagement with work. Results. Three out of 4 topics met minimum enrollment numbers; 22 of 24 participants completed follow-up as well as pretraining surveys. All would recommend the training to others and planned changes in personal and professional care. There were significant improvements in self-efficacy in using nondrug therapies, confidence in providing compassionate care, and unplanned absenteeism ( P < .05 for each). Conclusion. Training in integrative therapies is feasible and associated with significant improvements in clinicians’ sense of self-efficacy, confidence in providing compassionate care, and engagement with work. Additional studies are needed to determine the impact on quality of care and long-term workforce engagement.
Endovascular Abdominal Aortic Aneurysm Repair in Patients with Challenging Anatomy: Utility of the Hybrid Endograft
Authors: Jordan William D. , Naslund Thomas C. , Adelman Mark A. , Simoni Gene , Wirthlin Douglas J. 
Published: January 2017

Commercially available aortic stent grafts differ in construction and clinical advantage such that creating hybrid endografts by combining components from different manufacturers is sometimes useful. We describe a multicenter experience using hybrid endografts to treat patients with challenging anatomy. Hospital records and office charts were reviewed from four institutions. Hybrid endografts were defined as those with two types of covered stents in continuity to treat an abdominal aortic aneurysm (AAA). Indications for hybrid grafts were defined by type of endoleak and whether an endoleak was expected or unexpected as determined by the preoperative radiographic evaluation. Endpoints include intraoperative endoleaks, late endoleaks, change in aneurysm size, and rupture. Hybrid endografts were used to treat AAA (endovascular aneurysm repair [EVAR]) in 90 patients, representing 7.9% of the total multicenter experience. In 7 patients (7.8%), a hybrid graft construction as a secondary procedure successfully corrected a type 1 endoleak. In the remaining 83 patients (92.2%), hybrid grafts were created at the time of original EVAR to treat expected challenging anatomy or unexpected endoleaks. Hybrid endografts corrected 88 (97.8%) type 1 endoleaks, but 2 patients (2.2%) persisted with a proximal type 1 leak requiring conversion. During follow-up of 1 to 24 months, computed tomography and ultrasound surveillance, available for 73 patients (81.1%), detected one unresolved distal type 1 (1.1%) and seven type 2 (7.8%) endoleaks. Aneurysm size decreased at least 0.5 cm in 23 of 50 patients (46.0%) at 6 months and in 19 of 31 patients (61.3%) at 12 months. Aneurysm size increased at least 0.5 cm in 4 of 50 patients (8.0%) at 6 months and in 1 of 31 patients (3.2%) at 12 months. There were no ruptures. Hybrid endografts have favorable early and intermediate results in the treatment of AAA. Long-term follow-up will be needed to confirm the absence of significant adverse biomaterial interaction and the effect on AAA exclusion. We advocate the use of hybrid endografts as endovascular therapy for patients whose anatomy may be unsuitable for a single endograft type.
Clinically Diagnosed Nonocclusive Mesenteric Ischemia after Cardiopulmonary Bypass: Retrospective Study
Authors: Huwer Hanno , Winning J. , Straub U. , Isringhaus H. , Kalweit G. 
Published: January 2017

This retrospective study evaluates our experience with clinically diagnosed nonocclusive mesenteric ischemia after cardiopulmonary bypass. Twenty-three of 3,600 consecutive patients suffered from splanchnic malperfusion. Symptoms developed between day 2 and 6 postoperatively in 18 of 23 patients. Four of 23 patients had no abdominal symptoms. Laboratory evaluation revealed significantly higher serum lactate and creatine phosphokinase levels in the 18 symptomatic patients compared with those of a control group. Arteriography was performed in 20 cases and revealed nonocclusive splanchnic hypoperfusion. Risk factors for development of mesenteric ischemia include arrhythmias and low cardiac output. Patients with angiographically proven nonocclusive mesenteric ischemia were treated with intra-arterial bolus injection and subsequent intra-arterial infusion of tolazoline combined with heparin sodium. The overall mortality rate was 30% (7 of 23). Infusion therapy with tolazoline and heparin seems to be a successful treatment modality for clinically diagnosed mesenteric ischemia.
Genetic Therapy for Vein Bypass Graft Disease: Current Perspectives
Authors: Simosa Hector F. , Conte Michael S. 
Published: January 2017

Although continued progress in endovascular technology holds promise for less invasive approaches to arterial diseases, surgical bypass grafting remains the mainstay of therapy for patients with advanced coronary and peripheral ischemia. In the United States, nearly 400,000 coronary and 100,000 lower extremity bypass procedures are performed annually. The autogenous vein, particularly the greater saphenous vein, has proven to be a durable and versatile arterial substitute, with secondary patency rates at 5 years of 70 to 80% in the extremity.1 However, vein graft failure is a common occurrence that incurs significant morbidity and mortality, and, to date, pharmacologic approaches to prolong vein graft patency have produced limited results. Dramatic advances in genetics, coupled with a rapidly expanding knowledge of the molecular basis of vascular diseases, have set the stage for genetic interventions. The attraction of a genetic approach to vein graft failure is based on the notion that the tissue at risk is readily accessible to the clinician prior to the onset of the pathologic process and the premise that genetic reprogramming of cells in the wall of the vein can lead to an improved healing response. Although the pathophysiology of vein graft failure is incompletely understood, numerous relevant molecular targets have been elucidated. Interventions designed to influence cell proliferation, thrombosis, inflammation, and matrix remodeling at the genetic level have been described, and many have been tested in animal models. Both gene delivery and gene blockade strategies have been investigated, with the latter now reaching the stage of advanced clinical trials.
Phylogeny and classification of Davalliaceae on the basis of chloroplast and nuclear markers
Authors: Tsutsumi Chie , Chen Cheng-Wei , Larsson Anders , Hirayama Yumiko , Kato Masahiro 
Published: January 2017

AbstractDavalliaceae have been classified on the basis of morphological data or morphological and molecular data. The family has been divided into various genera, the circumscription of which may differ between authors. Previous phylogenetic analyses used limited numbers of genes and taxa. We studied the molecular phylogeny of the family by using two nuclear markers (LEAFY intron 1, gapCp intron) and a long chloroplast marker (atpB‐rbcL‐accD) in 55 specimens of 41 species. The results indicated that Davalliaceae are divided into seven clades, six of which coincide with the genera and sections sensu Kato & Tsutsumi. The relationships among the clades were inconsistent with respect to the markers analyzed, and a species tree derived from all datasets did not resolve the relationships. In addition, the clades were not well characterized to be classified at the genus level. Therefore, we propose to classify Davalliaceae in the single genus Davallia with seven sections, i.e., sect. Araiostegiella, sect. Davallia (comprising only D. canariensis), sect. Davallodes (including Araiostegia p.p. and Paradavallodes), sect. Humata (including Pachypleuria and Parasorus), sect. Scyphularia (s.l. = sect. Davallia sensu Kato & Tsutsumi excluding the type), sect. Trogostolon (s.l. = sect. Trogostolon sensu Kato & Tsutsumi), and sect. Cordisquama (s.l. = Wibelia sensu Kato & Tsutsumi). A key to the sections and a table of characters for the sections are provided.
A molecular phylogeny of the Laelia alliance (Orchidaceae) and a reassessment of Laelia and Schomburgkia
Authors: Peraza-Flores Lizandro N. , Carnevali Germán , van den Berg Cássio 
Published: January 2017

AbstractWe provide a molecular phylogenetic analysis of the Laelia alliance based on sampling of 20 of an estimated 24 species, and seven plastid regions plus nrITS 1 & 2 analyzed using maximum parsimony, maximum likelihood, and Bayesian inference. Furthermore, we used coded indels to evaluate their effect on the phylogenetic relationships and/or support values (bootstrap and posterior probabilities). Our results confirm the existence of two clades, the long known Laelia (endemic to México at middle to high elevations) and Schomburgkia (a more widely distributed taxon). Both clades were strongly supported by PP values and moderate BS; thus, we preferred to recognize them as separate genera with a reappraised morphology and taxonomic delimitation. The inclusion of coded indels in the analyses was of great utility; we could identify the probable hybrid origin of L. gouldiana and L. halbingeriana. We propose new combinations to accommodate the taxonomic changes resulting from our study. We transfer L. anceps subsp. anceps, L. anceps subsp. dawsonii, L. aurea, L. mottae, and L. rubescens to Schomburgkia, with the second taxon elevated to species level; the molecular evidence together with previous published work on the morphology, phenology and geography of the group support these decisions. Lastly, the recently described genus Encabarcenia is considered as a synonym of Schomburgkia and, as a result, a new combination is proposed.
Frozen Elephant Trunk and Antegrade Visceral Debranching in the Surgical Treatment of Type B Aortic Dissection: An Alternative Method
Authors: Tuncer Altug , Akbulut Mustafa , Adademir Taylan , Tas Serpil , Ak Adnan , Arslan Özgür , Erden Benay , Şişmanoğlu Mesut 
Published: January 2017

AbstractIntervention is inevitable in complicated Type B aortic dissections. Classical surgical procedures and endovascular interventions are far from ideal treatments due to their high risk of periprocedural complications and mortality. There is often a need for alternative method in cases of difficult anatomy. We present the combined use of frozen elephant trunk and antegrade visceral debranching methods in the treatment of a 54-year-old male patient with complicated Type B aortic dissection.
David-V Procedure in a Patient with Aortic Dilation and Competent Quadricuspid Aortic Valve: Are Genetics to Blame?
Authors: Hebeler Katherine , Squiers John , Baumgarten Heike , DiMaio J. Michael , Brinkman William 
Published: January 2017

AbstractQuadricuspid aortic valves (QAVs) are extremely rare. In this case study, we report a David-V valve-sparing aortic root replacement with reimplantation of a native QAV in a patient with aortic dilation, normal valve function, and a family history of aortic dissection. Microscopic pathological examination of the excised section of the aorta revealed scattered small foci of cystic medical degeneration throughout. A genetic predisposition for aortic dilation may be present in patients with QAV, even in the setting of a competent valve. Regular screening for aortic dilation in patients with known QAV should therefore be considered.
Development of bio-rights incentive scheme for participatory restoration and conservation of mangrove resources
Authors: SUHARTI SRI 
Published: January 2017

Abstract. Suharti S. 2017. Development of bio-rights incentive scheme for participatory restoration and conservation of mangrove resources. Biodiversitas 18: 121-128. Bio-rights incentive scheme is one strategy to accommodate efforts to increase economic benefits with efforts to prevent counterproductive activities to the environment (through restoration and conservation of natural resources). This study aims to assess the implementation of bio-rights incentive schemes, its achievements, and challenges in its implementation. The research was done by using survey method in Pesantren Village, Ulu Jami Sub-district, Pemalang, Central Java, Indonesia, which is the location of the pilot project established by Wetland International Indonesia (WII). The research was done in August to December 2014. The results showed that bio-rights incentives scheme could encourage the community to participate actively in restoration and conservation of mangrove resources. Implementation of bio-rights scheme was done through the provision of micro-credits to the community groups to develop activities that can generate sustainable income. Loan repayments and its interest was not in cash, but in the form of conservation service activities such as reforestation, habitat protection and the prevention of unsustainable land use. Through the bio-rights scheme, besides gaining financial benefits, villagers in Pesantren also received other benefits such as improvement of environmental conditions (widespread mangrove plantation, improvement in land productivity and the intensity of mangrove aquaculture).
Keywords: Bio-rights, conservation, mangrove, participatory, restoration
Forest type diversity on carbon stocks: Cases of recent land cover conditions of tropical lowland, swamp, and peatland forests in West Kalimantan, Indonesia
Authors: ASTIANI DWI , MUJIMAN MUJIMAN , RAFIASTANTO ANDJAR 
Published: January 2017

Abstract. Astiani D, Mujiman, Rafiastanto A. 2017. Forest type diversity on carbon stocks: Cases of recent land cover conditions of tropical lowland, swamp, and peatland forests in West Kalimantan, Indonesia. Biodiversitas 18: 137-144.Tropical forests constitute for a large concentrated carbon pools, ultimately in tropical peatland forest since this forest type sink carbon both in the vegetation and its underlying peat. However, these forests recently experienced a lot of pressures from anthropogenic disturbances. A study was conducted to estimate carbon stocks of degraded tropical lowland, swamp, and peatland forests in Kayong Utara West Kalimantan. Above ground survey was conducted using stratified sampling based on the differences in spectra of Landsat 7 ETM+ according to the land cover gradation or vegetation formations. The study area was classified based on the canopy closures and forest/landcover types and grouped into low and high degraded lowland forest, low and high degraded peat forest, low and high degraded swamp forest, shrub land, and mixed agricultural land. Aboveground carbon stocks in each group was estimated by purposively assessing all carbon sources within 5-11 plots of 20 m x 100 m area. Belowground carbon was also measured on peatland. Results show that among the groups, the highest to the lowest order of aboveground carbon sink consecutively were low degraded swamp, low degraded lowland, low degraded peatland, high degraded swamp, high degraded peatland, high degraded lowland forests, mixed agricultural land, and shrub land (269.1 to 46.3 ton C/ha) plus other biomass sources recruited from belowground roots. It is demonstrated that forest degradation and land cover changes reduce amount of above ground carbon stocks and thus could result large amount of carbon loss from forests. Surprisingly, our results demonstrated that 0.5-5.2 m belowground carbon in peatland contribute to large amount of carbon Each meter depth of those fibrist to hemist peat sinked ~634 ton C/ha. It is estimated that the 22,600 ha area of overall forest types/ land covers sink ~2.5 million of aboveground and ~5,570 ha peatland area hold ~9.2 million of below ground carbon. This amount of carbon is potential sink of carbon yet could be a huge losses if peatland forest and land cover changes continued.
Keywords: Aboveground carbon, belowground carbon stocks, degraded forest, land cover change, forest typesÂ