bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of antiplatelet/anticoagulant agents in elderly patients of chronic subdural hematoma: a case control study from a tertiary care centre
Authors: Potdar Nilesh Vishnu , S. Suresh Kumar , Kaplinghat Bhavadasan 
Published: May 2017

Background: Bleedings are well known risks of both antiplatelet and anticoagulant therapy and both therapies have historically been considered as risk factors for CSDH. The aim of the study was to evaluate the association between exposure to anticoagulant/antiplatelet therapy and chronic subdural haematoma (CSDH).Methods: Single institution case-control study was conducted in patients older than 60 years who visited our academic tertiary care Emergency Department from January 2012 to December 2016. Patients with CSDH were identified by review of case and controls were selected with a 1:3 ratio for gender, age (60 years), year of admission and recent trauma.Results: There were 124 cases and 372 controls included in the study. Both anticoagulant and antiplatelet agents were associated with an increased risk of CSDH with an OR of 1.22 (CI 95% 0.66-1.54) and 1.12 (CI 95% 0.68-1.54), respectively. While OR was 1.11 (CI 95% 0.54-2.32), 1.21 (CI 95% 0.61-2.45), and 0.53 (CI 95% 0.33-0.78) for patients receiving oral anticoagulants, ADP-antagonists, and Cox-inhibitors, respectively. History of recent trauma was an effective modifier of the association between anticoagulants and CSDH. OR of 1.69 (CI 95% 0.99-2.96) was found for patients with history of trauma and OR of 4.27 (CI 95% 2.23-8.32) for patients without history of trauma.Conclusions: Anticoagulant and antiplatelet therapy have a significant association with an increased risk of CSDH. This association appears even stronger in those patients under anticoagulant therapy, who develop a CSDH in the absence of a recent trauma.
Aetiology and outcome of anemia in patients with systemic lupus erythematosus
Authors: Sonawale Archana , Pasiddhi Suresh , Sabnis Nilakshi H. 
Published: May 2017

Background: Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that is greatly subject to the combined effect of genetic, environmental, demographic and geographical factors. Hematological manifestations are very common in SLE, with many patients presenting with anemia. The cause of Anemia could be varied, with Autoimmune hemolytic anemia, anemia of chronic disease, iron deficiency being the common causes. The aim of the present study was to estimate the proportion of patients with prevalence of different causes of anemia in SLE and it‘s association between immunological and clinical parameters and to correlate the severity of anemia with SLEDAI score and SLICC/ACR score.Methods: This was an observational and prospective study conducted on 52 patients satisfying ACR criteria for SLE and WHO definition of anemia. All patients underwent baseline investigations for hematological, biochemical parameters and immunological investigations for C3 and C4. Other special investigations were done as per the treating rheumatologists’ opinion. Patients were followed up after three months to evaluate the response to therapy.Results: In this study, most of the patients were in the age group between 20-50 years (94.22%) and female:male ratio was 13:1. At presentation 55.76% patients had severe anemia, 38.46% had moderate anemia and 5.78% had mild anemia. After therapy (three months) only 3.84% patients had severe anemia. The most common cause of anemia was AIHA (38.46%). Mean SLEDAI score at presentation was >20 but after three months therapy the score was reduced to 4. There was no correlation between aneamia and SLICC/ACR damage index.Conclusions: Anaemia usually occurs at the onset of SLE and its recurrence rate will become low after three months of therapy. SLEDAI scores, SLICC/ACR damage index and serum complement levels (C3 and C4) acts as good indices for assessment and follow up of SLE.
Laban no século XXI: Revisões necessárias
Authors: Moraes Juliana 
Published: May 2017

A continuidade das idéias de Laban nos países vencedores da II Guerra dependeu de sua transformação em um sistema de análise de movimentos, que incluiu extenso mas discreto processo de renomeação, como, por exemplo: o conceito alma/espiritualidade foi adaptado para personalidade, e a dicotomia harmonia/desarmonia foi renomeada integração/fragmentação.
“Kahlo em mim Eu e(m) Kahlo”: A Performance do meu Corpo Diferenciado
Authors: Oliveira Felipe Henrique Monteiro 
Published: May 2017

Este artigo se pauta na pesquisa desenvolvida para a elaboração de dissertação de mestrado, no Programa de Pós-Graduação em Artes Cênicas da UFRN, sob orientação da Profa. Dra. Nara Salles e objetiva refletir sobre as questões relacionadas aos artistas com corpos diferenciados nos processos de criação cênica, sobretudo no teatro pós-dramático.
THE EFFECTS OF PHYTASE SUPPLEMENTATIONS IN PREDICTING THE NON-PHYTATE PHOSPHORUS REQUIREMENT OF BROILERS IN STARTER PHASE
Authors: Wulandari Rateh , Poernama Ferry , Zuprizal Zuprizal , Dono Nanung Danar 
Published: May 2017

This study was aimed to observe the requirements of non-phytate phosphorus (NPP) with phytase supplementation in starter phase broiler. A total number of 1000 broiler (500 males and 500 females) were divided into 5 dietary treatments for 21 days rearing period. The treatment diets (P1-P5) were basal diets with 0.67% Calcium (Ca) and 60 FTU phytase that combined with NPP at different levels, i.e.: 0.420% (P1); 0.345% (P2); 0.270% (P3); 0.195% (P4); 0.120% (P5). The basal diet was a corn-soybean based diet that contained 0.097% Ca and 0.124% Phosphorus (P). The data were subjected to a one-way ANOVA using complete randomized design. Response variables that observed in current study were: feed intake, nett gain, feed convertion ratio, average body weight, mortality and toe ash. Measurement of responses due to the reduction of NPP supplementation on average body weight and toe ash were then followed subsequently by generating equation for quadratic curve y = ax2+bx+c to determinate the NPP requirement. Determination of the maximum response was done through ymaks = -b/2a. Results showed that based on average body weight, estimation of NPP requirement with phytase supplementation were 0.317% for the 0-10 days; 0.314% for the 11-21 days; and 0.315% for the the 0-21 days rearing periods. Based on toe ash content, estimation of NPP requirement with phytase supplementation was 0.990% (toe) for the 21 days rearing period. This study was aimed to observe the requirements of non-phytate phosphorus (NPP) with phytase supplementation in starter phase broiler. A total number of 1000 broiler (500 males and 500 females) were divided into 5 dietary treatments for 21 days rearing period. The treatment diets (P1-P5) were basal diets with 0.67% Calcium (Ca) and 60 FTU phytase that combined with NPP at different levels, i.e.: 0.420% (P1); 0.345% (P2); 0.270% (P3); 0.195% (P4); 0.120% (P5). The basal diet was a corn-soybean based diet that contained 0.097% Ca and 0.124% Phosphorus (P). The data were subjected to a one-way ANOVA using complete randomized design. Response variables that observed in current study were: feed intake, nett gain, feed convertion ratio, average body weight, mortality and toe ash. Measurement of responses due to the reduction of NPP supplementation on average body weight and toe ash were then followed subsequently by generating equation for quadratic curve y = ax2+bx+c to determinate the NPP requirement. Determination of the maximum response was done through ymaks = -b/2a. Results showed that based on average body weight, estimation of NPP requirement with phytase supplementation were 0.317% for the 0-10 days; 0.314% for the 11-21 days; and 0.315% for the the 0-21 days rearing periods. Based on toe ash content, estimation of NPP requirement with phytase supplementation was 0.990% (toe) for the 21 days rearing period.
FARMER'S KNOWLEDGE AND ECONOMIC ANALYSIS OF USING OF Chloris gayana GRASS AS BUFFALO FEED IN PASTORAL LAND
Authors: Rusdiana Supardi , Herdiawan Iwan 
Published: May 2017

The research objective was to obtain information about the knowledge of farmers towards Chloris gayana grass and economic feasibility of buffalo farming and farmer level as a first step for further activities. The study was conducted in the village Mekarsari Cibadak Subdistrict Lebak District of Banten Province, with a survey method in 2016, using questionaire and interviews to 20 farmers. Primary data were obtained from the farmer and secondary data obtained from the local Office. The collected data were tabulated and analyzed descriptively, quantitatively and economically. In male buffalo rearing, farmer’s profit was able to reach Rp3.170.000,-/head, with B/C ratio was 1.06. While buffalo cow-calf operation gave profit as Rp4.630.000,-/head, with B/C ratio was 1.06. It seems that keeping buffalo to produce meat was more porfitable compared to cow-calf operation. It resulted the development of bufallo in Kampung Curug Mekar Sari village Cibadak District of Lebak, Banten was slow. Planting Chloris gayana grass can support farmer and increase the economic scale of buffalo farmers.
Precisão altimétrica de modelo digital do terreno sob a vegetação obtido por interferometria de radar de abertura sintética de banda P
Authors: Gaboardi Clovis , Lübeck Dieter 
Published: May 2017

A tecnologia de Interferometria de Radar de Abertura Sintética (InSAR) operando na banda P (comprimento de onda de 75 cm) permite a obtenção de modelos digitais do terreno (MDT) sob a vegetação. Na região da construção da Usina Hidrelétrica (UHE) de Belo Monte, no município de Vitória do Xingu, estado do Pará, tornou-se necessário realizar o desmatamento da floresta sujeita a inundação provocada pela barragem em construção. Em 2014 foi realizado um levantamento com tecnologia InSAR da banda P para a obtenção do MDT sob a cobertura vegetal, a fim de delinear a área da floresta sujeita à inundação, para realizar a supressão da mesma. Após a supressão da floresta e antes da inundação, foi realizado um levantamento topográfico de precisão de 42 pontos do terreno, para validar a precisão altimétrica do MDT gerado.
Cyclometalated Complexes of Platinum and Gold with Biological Properties: State-of-the-Art and Future Perspectives
Authors: Jurgens Sophie , Kuhn Fritz E. , Casini Angela 
Published: May 2017

Background:
The inherent problems accompanying chemotherapy necessitate
the development of new anticancer approaches. The development of compounds that can
disrupt cancerous cellular machinery by novel mechanisms, via interactions with proteins
and non-canonical DNA structures (e.g. G-quadruplexes), as well as by alteration of the
intracellular redox balance, is nowadays focus of intense research. In this context, organometallic
compounds of the noble metals Pt and Au have become prominent experimental
therapeutic agents. This review provides an overview of the Pt(II) and Au(III) cyclometalated
compounds with a chelating ring containing a strong C-M σ -bond to improve
the stability of the compounds with respect to ligand exchange reactions and biological
reduction. Furthermore, these properties can be easily tuned by modification of either
the anionic cyclometalated or the ancillary ligands. Special focus has been set to
C^N, C^N^C, C^N^N and C^N^S platinum(II) and gold(III) pincer complexes regarding
their synthesis and biological mechanisms of action as anticancer agents.
Methods: A structured search of both chemical and medicinal databases for peerreviewed
research literature has been conducted. The quality of retrieved papers was appraised
using standard tools. The synthesis as well as the chemical and biological properties
of the described compounds were carefully reviewed and described. The findings
were outlined using a conceptual framework.

Results:
In this review we included 155 papers, the majority originating from high-impact
papers on the synthesis and biological modes of platinum(II) and gold(III) compounds.
Among them, 17 papers were highlighted to give an introduction to the use of Pt and Au
compounds with medicinal properties, mainly focussing on coordination compounds. The
synthesis and medicinal properties of organometallic compounds of various metals (such
as Fe, Ru, Ti) were outlined in 51 papers. These compounds included metallocenes, metallo-
arenes, metallo-carbonyls, metallo-carbenes (e.g. N-heterocyclic carbenes), and alkynyl
complexes. The C^N, C^N^C, C^N^N and C^N^S pincer complexes of platinum(
II) (46 papers) and gold(III) (44 papers) were discussed concerning their synthesis,
stability and advantages to develop therapeutic compounds. We strove to show the consistent
development of C^N, C^N^C, C^N^N and C^N^S platinum(II) and gold(III) pincer
complexes regarding their synthesis and biological modes from the early beginnings to
the most recent findings.

Conclusion:
This review supplies a profound overview of the development of organometallic
compounds for medicinal purposes, setting special focus to the synthesis and
stability of C^N, C^N^C, C^N^N and C^N^S pincer complexes of platinum(II) and
gold(III) and their use as anticancer agents.
Serum Levels of Vaspin and Its Correlation with Nitric Oxide in Type 2 Diabetic Patients with Nephropathy
Authors: Mihanfar Aynaz , Rahmati-Yamchi Mohammad , Mota Ali , Abediazar Sima , Pilehvar-Soltanahmadi Younes , Zarghami Nosratollah 
Published: May 2017

Background:
Diabetic Nephropathy (DN), a serious and prevalent complication of diabetes,
has been rapidly raising worldwide. Vaspin, as an adipokine with anti-diabetic effects, is predominantly
released from visceral adipose tissue. Moreover, vaspin has the stimulatory effect on nitric oxide (NO)
bioavailability through the activation of NO synthase.

Objective:
The aim of the present study was to investigate the serum levels of vaspin and their correlation
with NO metabolite in diabetic patients with normal renal function and renal insufficiency.

Methods:
Volunteers patients with non-nephropathy Type 2 Diabetic Mellitus (T2DM) as control
(n=40, age= 56.95±6.11 years) and patients with diabetic nephropathy (DN) (n=40, age=57.85±5.63
years) as case group were enrolled in this study, and serum samples were collected for the measurement
of vaspin levels by ELISA technique. Also, serum levels of NO metabolites were calorimetrically
assessed.

Results:
We found that vaspin levels significantly decreased in diabetic patients with nephropathic
condition as compared with diabetic patients with normal renal function (p <0.04). In addition, serum
levels of NO metabolites were significantly higher in diabetic patients with nephropathy in comparison
with non-nephropathic diabetics (p<0.001). When patients with DN were studied, vaspin levels positively
correlated with NO metabolites and Homeostasis model assessment of insulin resistance
(HOMA-IR) levels.

Conclusion:

This study showed that low serum vaspin levels may be a risk factor for nephropathy in
type II diabetic patients and increased levels of NO may be a defensive mechanism in the DN.
Managing Western Flower Thrips (Thysanoptera: Thripidae) on Lettuce and Green Peach Aphid and Cabbage Aphid (Hemiptera: Aphididae) on Broccoli with Chemical Insecticides and the Entomopathogenic Fungus Beauveria bassiana (Hypocreales: Clavicipitaceae)
Authors: Dara Surendra K. 
Published: May 2017

Aims:Lettuce and broccoli are high value vegetable crops in California. The western flower thrips,Frankliniella occidentalison lettuce, and the cabbage aphid,Brevicoryne brassicaeand the green peach aphid,Myzus persicaeon broccoli are important insect pests that are frequently managed with chemical insecticides.Observation:Efficacy of various chemical insecticides and the entomopathogenic fungusBeauveria bassianawas evaluated against these pests in field studies in the Santa Maria area of California. Some insecticides varied in their efficacy againstF. occidentalisfrom year to year and against different aphid species.Conclusion:A new insecticide sulfoxaflor provided good control of aphids on broccoli.Beauveria bassianademonstrated a potential for broccoli and lettuce integrated pest management.
Extending Inferential Group Analysis in Type 2 Diabetic Patients with Multivariate GLM Implemented in SPM8
Authors: Ferreira Fábio S. , Pereira João M.S. , Duarte João V. , Castelo-Branco Miguel 
Published: May 2017

Background:Although voxel based morphometry studies are still the standard for analyzing brain structure, their dependence on massive univariate inferential methods is a limiting factor. A better understanding of brain pathologies can be achieved by applying inferential multivariate methods, which allow the study of multiple dependent variables,e.g.different imaging modalities of the same subject.Objective:Given the widespread use of SPM software in the brain imaging community, the main aim of this work is the implementation of massive multivariate inferential analysis as a toolbox in this software package. applied to the use of T1 and T2 structural data from diabetic patients and controls. This implementation was compared with the traditional ANCOVA in SPM and a similar multivariate GLM toolbox (MRM).Method:We implemented the new toolbox and tested it by investigating brain alterations on a cohort of twenty-eight type 2 diabetes patients and twenty-six matched healthy controls, using information from both T1 and T2 weighted structural MRI scans, both separately – using standard univariate VBM - and simultaneously, with multivariate analyses.Results:Univariate VBM replicated predominantly bilateral changes in basal ganglia and insular regions in type 2 diabetes patients. On the other hand, multivariate analyses replicated key findings of univariate results, while also revealing the thalami as additional foci of pathology.Conclusion:While the presented algorithm must be further optimized, the proposed toolbox is the first implementation of multivariate statistics in SPM8 as a user-friendly toolbox, which shows great potential and is ready to be validated in other clinical cohorts and modalities.
Actualización sobre el síndrome de estrés tibial medial
Authors: Gómez García Santiago 
Published: May 2017

El síndrome de estrés tibial medial, SETM, una de las causas más comunes de dolor inducido por el ejercicio en las extremidades inferiores entre los practicantes de actividad física y deporte, como corredores y militares en formación, es un evento semiológico producido por lesiones repetitivas de estrés mecánico en la región medial de la tibia. No suele revestir gravedad, pero si no se trata adecuadamente puede evolucionar a lesiones incapacitantes, como la llamada fractura por estrés de la tibia. Existen factores de riesgo que contribuyen al desarrollo de la patología entre los que cabe mencionar el tipo de actividad, las inadecuadas técnicas de entrenamiento, las condiciones del terreno y el tipo de calzado utilizado, también la pronación anormal de la articulación subastragalina, el sexo femenino, un índice de masa corporal elevado, así como la disminución de la densidad mineral ósea. El diagnóstico generalmente se establece a través del interrogatorio y el examen físico, ya que las radiografías solo sirven para descartar fracturas por estrés de la tibia, y exámenes de imágenes más costosos no se justifican. El tiempo de recuperación de los afectados por esta patología es bastante prolongado, lo que propicia la tendencia al abandono del tratamiento y, así, desfavorece la consecución de los objetivos terapéuticos propuestos. El tratamiento estándar de oro es la terapia física; sin embargo, existen otras modalidades terapéuticas con prometedoras perspectivas, entre las que sobresale la terapia por ondas de choque extracorpóreas, respecto de la cual los estudios disponibles son todavía insuficientes, pues tanto la fisiopatología del SETM, como su prevención y su tratamiento aún no están claros. En atención a lo anteriormente expuesto, este artículo presenta una revisión del estado del arte de los aspectos fundamentales de la patología.
Solución para el último teorema de Fermat
Authors: Porras Ferreira José William 
Published: May 2017

El último teorema de Fermat (FLT), (1637), establece que, si n es un entero mayor que 2, entonces es imposible encontrar tres números naturales x, y y z donde dicha igualdad se cumple siendo (x, y)> 0 en xn + yn = zn. Este artículo muestra la metodología para probar el último teorema de Fermat por Reducción ad absurdum, el teorema de Pitágoras y la propiedad de triángulos similares, conocidos en el siglo XVII, cuando Fermat enunció el teorema.
El Centro de Investigación de la Cultura Física de la Escuela Militar de Cadetes
Authors: López Moreno Sara Constanza 
Published: May 2017

Durante los últimos años, la importancia de la adquisición de una condición física adecuada dentro de la formación de los estudiantes de la Escuela Militar, había sido un poco relegada, dando prioridad a la formación académica y militar, convirtiéndose así en un problema que debía ser abordado de manera directa. La existencia de ciertas debilidades en la forma en que la Escuela Militar estaba preparando a sus cadetes y alféreces en el desarrollo de sus competencias físicas, se identifica en la conjunción de múltiples factores, los cuales fueron determinantes para empezar un cambio profundo en este aspecto tan importante de la formación. Con este estudio se pretende averiguar el impacto que han tenido algunas nuevas políticas generadas desde la Dirección de la Escuela Militar, con referencia a la preparación física de los estudiantes, en las cuales se ha consagrado una mayor importancia al mejoramiento constante en la adquisición, desarrollo y mantenimiento de las competencias físicas de los futuros oficiales.
Comunidad ecológica-política de América Latina y el Caribe: una identidad proyecto para la globalidad
Authors: Ariza Ruiz Efrén Danilo , Ruiz Sarmiento Mario Humberto 
Published: May 2017

Esta recensión persigue identificar el Paso de “la identidad como mismidad a la identidad como diversidad en los tiempos actuales, en la búsqueda de consolidar una comunidad ecológica-política de América Latina y el Caribe (ALC) que sería la forma de aparecer una identidad proyecto de vida para la globalidad. Se defiende aquí la necesidad de que los ciudadanos de ALC nos organicemos como una comunidad de sentimientos comunes con el designio de adquirir la capacidad para acceder al poder social tradicional (político, económico e ideológico-cultural y de la industria de la comunicación) y con éste a nuestra disposición impulsar y lograr efectivamente edificar una comunidad política ecológica y que la filosofía intercultural puede brindar las condiciones de posibilidad de establecer un polílogo abierto en condiciones materiales y teóricas de igualdad entre las tradiciones culturales que existen en nuestra América que permita construir la comunidad propuesta con el poder popular suficiente para dominar y someter la actividad depredadora, iniciada desde 1492, y actualizada en las empresas multinacionales extractivas de nuestros recursos naturales y responsables del deterioro ambiental, apoyadas por las élites de los Estados patrimonialistas arbitrarios y autoritarios, siendo, algunos, miembros de la CELAC.
La resistencia y la sobrevivencia de la justicia indígena en Colombia
Authors: Ruiz Morato Natalia 
Published: May 2017

Se realizó una investigación histórica y socio-jurídica sobre el funcionamiento de la Jurisdicción Especial Indígena para ubicar las tensiones y dificultades entre la jurisdicción ordinaria. El estudio determinó que existen relaciones no amigables entre justicia indígena y la justicia ordinaria y una negación de la aplicación de la Ley de Origen como forma válida de solución de conflictos de los pueblos indígenas en Colombia. Como principal resultado se evidenció la imposibilidad del sistema jurídico colombiano de armonizar el pluralismo jurídico creado en la Constitución Nacional de Colombia, por lo cual la Jurisdicción Especial Indígena es forma de supervivencia y reivindicación de los grupos indígenas en Colombia. Como alternativa de salida se propone la incorporación de esquemas democráticos deliberativos para sociedades multiétnicas.