bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: A New Route to Benzo(a)naphthacene‐8,13‐diones: Synthesis and Revision of the Structure Proposed for G2N.
Authors: HAUSER F. M. , CARINGAL Y. 
Published: May 2016

AbstractAs outlined in the reaction scheme, the hexahydrobenzonaphthacenone (III) is formed by cyclocondensation of the phthalide sulfone (I) with the hydrophenanthrone (II).
ChemInform Abstract: Diisophorone and Related Compounds. Part 23. A Rearrangement of the Tricyclo(7.3.1.02,7)tridecane to the Bicyclo(4.2.1)nonane‐7‐spiro‐2′‐(tetrahydrofuran) Ring System.
Authors: KURZER F. , ALLEN A. A. 
Published: May 2016

AbstractThe formation of the spiro compound (II) proceeds via a Baeyer‐Villiger oxidation, a recyclisation and a pinacol rearrangement.
ChemInform Abstract: 1,4‐Dihydronaphthoquinones, Hydroindoloquinones, Benzofurans, and Benzothiophenes as Inhibitors of 5‐Lipoxygenase. Synthesis and Structure‐Activity Studies.
Authors: YAMASHITA A. , SCHAUB R. G. , BACH M. K. , WHITE G. J. , TOY A. , GHAZAL N. B. , BURDICK M. D. , BRASHLER J. R. , HOLM M. S. 
Published: May 2016

AbstractThe aryl bromides (I) and (VIII) are lithiated, coupled with the chromium complex (II), and subsequently O‐methylated to form the corresponding chromium carbene complexes (IV) and (IX).
ChemInform Abstract: Organophosphorus Chemistry. Part 13. The Behavior of 3‐Aryliminoxindoles Toward Alkyl Phosphites.
Authors: ABDOU W. M. , ABD EL‐RAHMAN N. M. , MAHRAN M. R. H. 
Published: May 2016

AbstractAcOH (or H2O) is essential for the reaction of the title indoles (I) with trialkylphosphites (II) to give the indolylphosphonates (III).
ChemInform Abstract: Ruthenium‐Catalyzed Dehydrogenative N‐Heterocyclization: Indoles from 2‐Aminophenethyl Alcohols and 2‐Nitrophenethyl Alcohols.
Authors: TSUJI Y. , KOTACHI S. , HUH K.‐T. , WATANABE Y. 
Published: May 2016

AbstractThe 2‐aminophenethyl alcohol (IV), prepared from the corresponding 2‐nitrotoluene derivative (I) as shown in the reaction scheme, undergoes Ru‐catalyzed cyclization to form the indole (V).
ChemInform Abstract: A Synthetic Route to Bicyclic Pyrazolenines via 3‐Chloropyrazolines and the Ring Opening of Pyrazolenines to Diazoalkenes.
Authors: NAKANO Y. , HAMAGUCHI M. , NAGAI T. 
Published: May 2016

AbstractThe 1,3‐dipolar cycloaddition reaction of the diazoalkanes (I) with the chlorofumarate (II) yields the 3‐chloropyrazolines (III) which undergo dehydrohalogenation on treatment with triethylamine, forming the 3H‐pyrazoles (IV).
ChemInform Abstract: Potential Antitumor Agents. Part 59. Structure‐Activity Relationships for 2‐Phenylbenzimidazole‐4‐carboxamides, a New Class of “Minimal” DNA‐Intercalating Agents which May not Act via Topoisomerase II.
Authors: DENNY W. A. , REWCASTLE G. W. , BAGULEY B. C. 
Published: May 2016

AbstractThe diaminobenzoic acids (IV) are prepared via Curtius rearrangement of the azide (III) or via oxidation, nitration, and reductive debromination of the isatin (V).
ChemInform Abstract: A Novel Method for the Amination of 4,6‐Dinitrobenzofuroxan via Meisenheimer Complexes.
Authors: GOEHRMANN B. + , NICLAS H.‐J. 
Published: May 2016

AbstractAccording to (IIIa), all the Meisenheimer complexes (IIIa)‐(IIIc) are prepared from dinitrobenzofuroxan (I) and the respective alkali amides.
ChemInform Abstract: Synthesis of n‐Butyl 2(H)‐Oxonaphtho(1,2‐b)pyran‐4‐acetate and n‐Butyl 3(H)‐Oxonaphtho(2,1‐b)pyran‐1‐acetate and Their Reactions.
Authors: SOLIMAN A. Y. , EL‐NAGDY S. , BAKEER H. M. , MOUSTAFA M. M. , SALEH R. M. 
Published: May 2016

AbstractThe esters (I) and (XVI) are prepared by treatment of the corresponding acids with butanol and subjected to a series of reactions as shown for (I).
ChemInform Abstract: 4‐Alkyl‐3‐phenyl‐2H‐1‐benzopyran‐2‐ones and Related Compounds as Potential Pesticides.
Authors: SANGWAN N. K. , VERMA B. S. , MALIK O. P. , DHINDSA K. S. 
Published: May 2016

AbstractTwelve compounds of type (IV) and four compounds of type (VI) are prepared and tested for in vitro antifungal activity.
ChemInform Abstract: The Cyclization of Benzylaminonitriles. Part 7. Regiospecific Formation of Methoxysubstituted Isoquinolin‐4‐ones Using Methylthio Activating Groups.
Authors: GAVIN J. P. , WAIGH R. D. 
Published: May 2016

AbstractCyclization of the dimethoxybenzyl derivatives (I) yields preferably the 5,6‐dimethoxyisoquinolines (II), the desired 7,8‐dimethoxy derivatives (III) being only by‐products.
ChemInform Abstract: Syntheses of 1,3‐Disubstituted N‐Oxy‐β‐carbolines by the Pictet‐Spengler Reactions of N‐Oxy‐tryptophan and ‐tryptamine Derivatives.
Authors: HERMKENS P. H. H. , VAN MAARSEVEEN J. H. , COBBEN P. L. H. M. , OTTENHEIJM H. C. J. , KRUSE C. G. , SCHEEREN H. W. 
Published: May 2016

AbstractN‐Hydroxy‐ and N‐alkoxytryptophans are prepared by a simple and general method and subjected to Pictet‐Spengler reactions.
ChemInform Abstract: Synthesis and Biological Activity of Some New 2‐Chlorophenothiazine Derivatives.
Authors: EL‐EZBAWY S. R. , ALSHAIKH J. A. 
Published: May 2016

AbstractThe (chloroacetyl)chlorophenothiazine (I) reacts with the aromatic or heteroaromatic mercaptans (II) to yield the (arylthioacetyl)chlorophenothiazines (III).
ChemInform Abstract: Synthesis of α‐Substituted Hydroazepine Derivatives from ε‐Caprolactam.
Authors: NAGASAKA T. , KOSEKI Y. , HAYASHI H. , YASUDA Y. , HAMAGUCHI F. 
Published: May 2016

AbstractConsecutive treatment of ε‐caprolactam (I) with sodium hydride and ethyl chloroformate (II) leads to the formation of 1‐(ethoxycarbonyl)hexahydro‐2H‐azepin‐2‐one (III) which is reduced with sodium borohydride in ethanol (IV) to form the 2‐ethoxyhexahydroazepine (V).
ChemInform Abstract: Pentacoordinated Molecules. Part 79. Pentacoordinate Acyclic and Cyclic Anionic Oxysilicates. A 29Si NMR and X‐Ray Structural Study.
Authors: SWAMY K. C. K. , CHANDRASEKHAR V. , HARLAND J. J. , HOLMES J. M. , DAY R. O. , HOLMES R. R. 
Published: May 2016

AbstractVariable‐temp.
ChemInform Abstract: A Novel Synthesis of α‐Fluoroalkylvinyl‐ or α‐Fluoroepoxyalkyl‐phosphonates.
Authors: SHEN Y. , LIAO Q. , QIU W. 
Published: May 2016

AbstractThe use of MeLi instead fo BuLi in the first reaction step shifts the product ratio markedly to the epoxide (V); thus, the ratio of (IVa):(Va) with MeLi is 2:51.
ChemInform Abstract: Synthesis, Isomer Separation, and Metal Complexation Studies of Aza‐ and Oxaphosphands, a Class of Hard/Soft Dinucleating Phosphine Macrocycles.
Authors: WEI L. , BELL A. , AHN K.‐H. , HOLL M. M. , WARNER S. , WILLIAMS I. D. , LIPPARD S. J. 
Published: May 2016

AbstractThe two hybrid, asym.
ChemInform Abstract: Synthesis and Coordination Chemistry of the Hexadentate Ligands 1,4,7‐Tris(2‐hydroxybenzyl)‐1,4,7‐triazacyclononane (H3L1) and 1,4,7‐Tris(3‐tert.‐butyl‐2‐hydroxybenzyl)‐1,4,7‐triazacyclononane (H3L2). Crystal Structures of (HL1CuII) and (L2FeIII)acacH.
Authors: AUERBACH U. , ECKERT U. , WIEGHARDT K. , NUBER B. , WEISS J. 
Published: May 2016

AbstractA third five‐coordinate Cu complex (red, 31% yield) is obtained under the same conditions as (VI) (green) without addition of HClO4.
ChemInform Abstract: Monocyclopentadienylzirconium and ‐hafnium Alkyls: Synthesis, Hydrogen‐Transfer Reactions, and Catalytic Features in the Reactivity with α‐Olefins. X‐Ray Structure of CpZr(η4‐butadiene)(dmpe)Cl (dmpe: 1,2‐Bis(dimethylphosphino)ethane).
Authors: WIELSTRA Y. , GAMBAROTTA S. , SPEK A. L. 
Published: May 2016

AbstractThe structure of a new class of butadiene complexes (III) is confirmed by an X‐ray analysis of (IIIa) ( P21/n, Z=4), which can be synthesized more conveniently on a large scale by reduction of (IV) in the presence of (V).
ChemInform Abstract: Multidentate Lewis Acids. Synthesis, Structure, and Reactions of Complexes of Bidentate Zirconium Trichloride Alkoxides.
Authors: GALEFFI B. , SIMARD M. , WUEST J. D. 
Published: May 2016

AbstractThe simple preparation of the mer‐octahedral complex (III) offers the opportunity to synthesize the THF‐adduct (V) of a bidentate zirconiumtrichloride alkoxide.
ChemInform Abstract: Synthesis, Structure, and Reactivity of (Phosphoranylidenephosphine)pentacarbonyltungsten Complexes. Another Access to the Phosphorus‐Carbon Double Bond.
Authors: LE FLOCH P. , MARINETTI A. , RICARD L. , MATHEY F. 
Published: May 2016

AbstractThe title complexes (III) are synthesized as shown for (IIIa)‐(IIId).
ChemInform Abstract: Transmetalation of Tetranuclear Copper(I) Complexes with an Fe(NS)3 Reagent.
Authors: DAVIES G. , EL‐SAYED M. A. , EL‐TOUKHY A. , HENARY M. 
Published: May 2016

AbstractStoichiometric transmetalation of tetranuclear Cu(I) complexes (I) by (II) is preceded by electron transfer from Cu(I) to Fe(III) leading to Fe(II)‐containing products (III), whereas the reactions of (III) with (IV) (or (II)) give Fe(III)‐containing dimers (VI) and trimers (VIII) after oxidation.
ChemInform Abstract: Synthesis, Crystal Structure, and Magnetic Properties of a Pyrazolate‐Bridged Binuclear Copper(II) Complex.
Authors: DOMAN T. N. , WILLIAMS D. E. , BANKS J. F. , BUCHANAN R. M. , CHANG H.‐R. , WEBB R. J. , HENDRICKSON D. N. 
Published: May 2016

AbstractThe asymmetric Schiff‐base ligand (I), formed by condensation of salicylaldehyde and 1,4‐diaminobutanol‐(2), reacts with a copper salt in the presence of pyrazole to give the new title complex (IV) (space group P21/c, Z=4).
ChemInform Abstract: Catalytic Functionalization of C‐H Bonds by Isonitrile Insertion. Preparation, Characterization, and Reactivity of RhCl(PR3)2(CNR′).
Authors: JONES W. D. , HESSELL E. T. 
Published: May 2016

AbstractFrom the Rh(I) complexes (IV) prepared all of the neopentyl complexes (IVa)‐(IVc) produce the isonitrile insertion compound (VI) on irradiation in benzene (V) solvent.
ChemInform Abstract: Synthesis of Mono‐ and Sesquiterpenoids. Part 18. Stereocontrolled Synthesis of (‐)‐Prezizanol, (‐)‐Prezizaene, Their Epimers and (‐)‐Allokhusiol.
Authors: SAKURAI K. , KITAHARA T. , MORI K. 
Published: May 2016

AbstractThe β‐keto ester (I), available from (R)‐(+)‐pulegone, is used as the common starting material for the synthesis of 5‐epiprezizanol (XI), 5‐epiprezizaene (XII), prezizanol (XV), prezizaene (XVI) and allokhusiol (XVII).
ChemInform Abstract: The Structure of Euphorianin (I), an Ingol Diterpenoid from Euphorbia poisonii.
Authors: FAKUNLE C. O. , OKOGUN J. I. , EKONG D. E. , CONNOLLY J. D. , RYCROFT D. S. 
Published: May 2016

AbstractThe residual uncertainty in the structure of the title compound (I), an ingol diterpenoid from the latex of Euphorbia poisonii, is resolved by nuclear Overhauser enhancement difference experiments which revealed the configuration at C‐19 to be S. In this paper spectroscopic properties of compound (I) and some transformation products, e.g. (II) are reported.
ChemInform Abstract: Convenient Synthesis of 1,2,4‐Tri‐O‐acetyl‐5‐deoxy‐5‐((R)‐ and (S)‐ethylphosphino and phenylphosphino)‐3‐O‐methyl‐α,β‐D‐xylopyranoses and Their Phosphinothioyl Derivatives.
Authors: HANAYA T. , SHIGETOH N. , YAMAMOTO H. , ARMOUR M.‐A. , HOGG A. M. 
Published: May 2016

AbstractThe isomeric ethylphosphinyl‐xylopyranose acetates (V) and, as an inseparable mixture, (VI) are prepared from the xylofuranose (IIIa) (or, with comparable yields, from (IIIb)).
ChemInform Abstract: Synthesis and Antiviral and Cytotoxic Activity of Iodohydrin and Iodomethoxy Derivatives of 5‐Vinyl‐2′‐deoxyuridines, 2′‐Fluoro‐2′‐deoxyuridine, and Uridine.
Authors: KUMAR R. , XU L. , KNAUS E. E. , WIEBE L. I. , TOVELL D. R. , TYRRELL D. L. , ALLEN T. M. 
Published: May 2016

AbstractAddition of hypoiodite to the vinyluridines (I) yields regioselectively the iodohydrins (II).
ChemInform Abstract: Synthesis and β‐Lactamase Inhibitory Activity of 3‐Cyano‐3‐cephem Derivatives.
Authors: NISHIMURA S. , YASUDA N. , SASAKI H. , MATSUMOTO Y. , KAMIMURA T. , SAKANE K. , TAKAYA T. 
Published: May 2016

AbstractThe phenylacetylaminocephem (XII) is prepared from (XI) analogously to the 7‐unsubstituted product (IX) from (VI).
ChemInform Abstract: Absorption, Luminescence, IR and Raman Spectroscopy of a Novel Polynuclear Neodymium Compound: Nd2(OH)3(ClO4)3·5 H2O.
Authors: HUSKOWSKA E. , LEGENDZIEWICZ J. , HANUZA J. 
Published: May 2016

AbstractThe IR and Raman spectra of the title compound (synthesis not described) are discussed in relation to the crystal structure (monoclinic, C2/c, Z=4).
ChemInform Abstract: Thermochemical Studies in the Sodium‐Chromium‐Oxygen System
Authors: SAMPATH S. , SALI S. K. , JAYADEVAN N. C. 
Published: May 2016

Abstract(TG, DTA, XRD) are performed because of the importance of NaCrO2 with respect to the corrosion of stainless steel by oxygen contaminated sodium in fast reactors.
ChemInform Abstract: Trivalent Lead as an Intermediate in the Oxidation of PbII and the Reduction of PbIV Species.
Authors: MOSSERI S. , HENGLEIN A. , JANATA E. 
Published: May 2016

AbstractElectron pulse and γ‐radiolysis experiments with Pb(ClO4)2 solutions are performed for pH < 7.0 and > 11.4.
ChemInform Abstract: Matrix Reactions of Germane and Oxygen Atoms. IR Spectroscopic Evidence for Germylene‐Water Complex, Gemanone, Germanol, Hydroxygermylene, and Germanic Acid.
Authors: WITHNALL R. , ANDREWS L. 
Published: May 2016

AbstractThe photochemical reaction of GeH4 and O3 in solid argon is studied by IR spectroscopy.
ChemInform Abstract: (BEDO)2.4I3: The First Robust Organic Metal of BEDO‐TTF.
Authors: WUDL F. , YAMOCHI H. , SUZUKI T. , ISOTALO H. , FITE C. , KASMAI H. , LIOU K. , SRDANOV G. , COPPENS P. , MALY K. , FROST‐JENSEN A. 
Published: May 2016

AbstractResults on the title salt (II) are presented (temp.
ChemInform Abstract: Homochiral Fluoroorganic Compounds. Synthesis of the Two Enantiomers of (Z)‐3‐Fluoro‐4‐phenyl‐1‐(p‐tolylsulfonyl)but‐3‐en‐2‐ol Through Microbial Reduction.
Authors: BERNARDI R. , BRAVO P. , CARDILLO R. , GHIRINGHELLI D. , RESNATI G. 
Published: May 2016

AbstractThe microbial reduction of the fluorobutenone (I) yields either the (S)‐ or (R)‐configurated fluorobutenols (II) in enantiomerically pure form.
ChemInform Abstract: Chiral Synthesis via Organoboranes. Part 24. B‐Allylbis(2‐isocaranyl)borane as a Superior Reagent for the Asymmetric Allylboration of Aldehydes.
Authors: BROWN H. C. , RANDAD R. S. , BHAT K. S. , ZAIDLEWICZ M. , RACHERLA U. S. 
Published: May 2016

AbstractThe title reagent (V) ‐ prepared in three steps via hydroboration of (+)‐2‐carene (I) ‐ is shown to undergo asymmetric allylboration with a variety of aldehydes such as (VI) to give the corresponding homoallylic alcohols in 94‐99% e.e.
ChemInform Abstract: Allylic Substitution by Carbon Nucleophiles on 4‐Bromo‐4‐methyl‐2‐pentenoate: Anti‐Michael Regioselectivity.
Authors: ROUX‐SCHMITT M.‐C. , PETIT A. , SEVIN A. , SEYDEN‐PENNE J. , NGUYEN TRONG ANH NGUYEN TRONG ANH 
Published: May 2016

AbstractReaction of carbanions of nitriles such as (II), (VI) with the tert.‐bromoester (I) does not give cyclopropanes but the products (III), (IV), (V) or (VII), (VIII) are formed.
ChemInform Abstract: Diels‐Alder Reaction of Chiral Dienes. Remarkable Effect of Dienophile Polarity Upon Diastereoface Selectivity.
Authors: HAMADA T. , SATO H. , HIKOTA M. , YONEMITSU O. 
Published: May 2016

AbstractThe optically active 5‐methoxy(benzyloxy)‐1,3‐dienes (I) are subjected to cycloaddition reaction with various dienophiles such as (II), (V), or (VII) to give chiral Diels‐Alder adducts.
ChemInform Abstract: Transition‐Metal‐Induced Generation of C2H4 from 1,7‐Octadiene: Regiospecific Activation of Internal C‐C Bonds Instead of Metathesis‐Like Coupling of Terminal CH2 Groups.
Authors: STEINRUECK N. + , DANGE O. , STOECKIGT D. + , SCHWARZ H. 
Published: May 2016

AbstractThe reaction of "naked" transition‐metal ions M+ (M: Fe, Ni, Cr) with 1,7‐octadiene is one of the rare examples of directed activation of C‐C bonds without prior C‐H bond activation.
ChemInform Abstract: Intramolecular Interconversion of syn‐ and anti‐Tricarbonyl(1‐ethoxy‐1,2‐dihydrocyclobutabenzene)chromium. Trapping of the ortho‐Quinodimethane Intermediate.
Authors: KUENDIG E. P. + , BERNARDINELLI G. , LERESCHE J. , ROMANENS P. 
Published: May 2016

AbstractThe reversible isomerization of syn‐(I) (P212121, Z=4) to anti‐(III) occurs without cleavage of metal‐ligand bonds, as demonstrated through a (4 + 2) cycloaddition with (IV) as the dienophile, which leads to the trapping of the intermediate (II).
ChemInform Abstract: Stereoelectronic Effects in the Deprotonation of Arylalkyl Radical Cations: meso‐Ethylanthracenes.
Authors: TOLBERT L. M. , KHANNA R. K. , POPP A. E. , GELBAUM L. , BOTTOMLEY L. A. 
Published: May 2016

AbstractOxidations of the title compounds (III) and (IV) are performed to study further the "ethyl" effect, that is, the abolition of carcinogenic activity when certain otherwise carcinogenic polynuclear aromatic hydrocarbons are substituted at the meso position by an ethyl group.
ChemInform Abstract: Oxidation of Olefins by Oxygen with a Mixed Palladium/Silver Nitrite Catalyst in Alcohols.
Authors: SAGE J.‐M. , GORE J. , GUILMET E. 
Published: May 2016

AbstractThe terminal olefin (I) is treated with oxygen in the presence of a palladium phosphine catalyst and a nitrite in alcohols to form the methyl ketone (II).
ChemInform Abstract: A Surprising Observation Concerning Sodium Hydride Based Complex Reducing Agents.
Authors: NORDAHL A. , CARLSON R. 
Published: May 2016

AbstractComplex reducing agents (CRA) prepared from NaH, an alkoxide, and a transition metal salt are known to reduce C=C double bonds (Ni‐CRA) and carbonyl groups (Zn‐CRA).
ChemInform Abstract: Hydrogenolysis of α,β‐Epoxy Ketone and Ester to Aldol in Pd(0)/HCOOH/ Et3N and H2/Pd/C Reduction Media.
Authors: TORII S. , OKUMOTO H. , NAKAYASU S. , KOTANI T. 
Published: May 2016

AbstractVarious α,β‐epoxy ketones are treated with triethylammonium formate in the presence of a Pd(II) phosphine catalyst or directly hydrogenated to give hydroxy ketones, hydroxy epoxides, or diols.
ChemInform Abstract: (2‐(Benzyloxy)‐1‐(N‐2,6‐xylylimino)ethyl)samarium as a Synthetic Equivalent to α‐Hydroxyacetyl Anion.
Authors: MURAKAMI M. , KAWANO T. , ITO Y. 
Published: May 2016

AbstractThe title samarium compound (IV) ‐ prepared in situ from benzyl chloromethyl ether (I) ‐ is shown to be a valuable synthetic equivalent of the α‐hydroxyacetyl anion and may replace multistep procedures which are used up to now for the assembly of a dihydroxyacetone side chain in the synthesis of natural compounds.
ChemInform Abstract: Formation of 1‐(Trimethylsilyl) 1,4‐Dienes by Vinylation of Allyltrimethylsilane in the Presence of the Palladium(0)/Silver Salt System.
Authors: KARABELAS K. , HALLBERG A. 
Published: May 2016

AbstractThe presence of silver salts enhances the rate of the title reaction, suppresses the desilylation and promotes the formation of 1,4‐dienes.
ChemInform Abstract: Reactions of 2,2‐Difluoroalkenylboranes with Halogens in the Presence of Bases. A Novel Synthesis of Symmetrically Disubstituted 1,1‐Difluoro‐1‐alkenes and 1,1‐Difluoro‐2‐iodo‐1‐alkenes.
Authors: ICHIKAWA J. , SONODA T. , KOBAYASHI H. 
Published: May 2016

AbstractThe trifluoroethyl tosylate (I) reacts with LDA and the trialkylboranes (II) to give the intermediate vinylboranes (III) which are rearranged and deboronated upon treatment with sodium methoxide and bromine to produce the 1,1‐difluoroalkenes (IV).
ChemInform Abstract: Electrogenerated Nickel(0)‐Catalyzed Carbon Dioxide Incorporation into α,ω‐Diynes.
Authors: DERIEN S. , DUNACH E. , PERICHON J. 
Published: May 2016

AbstractThe influences are studied which are exerted by solvent, temp., CO2 pressure, and catalyst on product formation in the reactions of (I) and 1,6‐heptadiyne with CO2 (II).
ChemInform Abstract: Cobalt(II)‐Catalyzed Coupling Reaction of α,β‐Unsaturated Compounds with Aldehydes by the Use of Phenylsilane. New Method for Preparation of β‐Hydroxy Nitriles, Amides, and Esters.
Authors: ISAYAMA S. , MUKAIYAMA T. 
Published: May 2016

AbstractBenzaldehyde (Ia) is coupled with the acrylonitriles (II) in the presence of phenylsilane (III) and a cobalt bisdiketonate to form the intermediate β‐siloxy nitriles (IV) which are hydrolyzed, yielding the hydroxy analogues (V).
ChemInform Abstract: Construction of Medium‐ and Large‐Sized Cyclic β‐Keto Esters (or Nitriles) via One‐Pot Three‐Carbon Ring Expansion of Carbocyclic β‐Keto Esters and Its Application to the Synthesis of (‐)‐Muscone.
Authors: XIE Z.‐F. , SAKAI K. 
Published: May 2016

AbstractNine cyclic β‐keto esters such as (I) are treated with potassium tert‐butoxide in DMSO to give the corresponding ring‐enlarged products, e.g. (II), via intramolecular aldol condensation followed by retro‐aldol cleavage.
ChemInform Abstract: Synthesis of Chiral Triamine Ligands from Ephedrine and Pseudoephedrine.
Authors: DIETER R. K. , LAGU B. , DIETER J. W. , DEO N. , PENNINGTON W. T. 
Published: May 2016

AbstractPseudoephedrine (I) is N‐alkylated with the chlorides (II) in the presence of a base to give the derivatives (III).
ChemInform Abstract: The Novel Catalytic Action of Clay Montmorillonite on the Additions of Silyl Ketene Acetals to α,β‐Acetylenic Esters.
Authors: ONAKA M. , MIMURA T. , OHNO R. , IZUMI Y. 
Published: May 2016

AbstractThe coupling of the propiolates (I) with the silyl ketene acetals (II) or (VII) is performed in the presence of iron montmorillonite or trimethylsilyl triflate to give different adducts as outlined in the reaction scheme.
ChemInform Abstract: Enantioselective Synthesis of Furyl Alcohols by Catalytic Asymmetric Addition of Diethylzinc to Furanaldehydes.
Authors: VAN OEVEREN A. , MENGE W. , FERINGA B. L. 
Published: May 2016

AbstractThe enantioselective reaction mentioned in the title is achieved in the presence of chiral amino alcohols.
ChemInform Abstract: Diastereoselective Addition of Organometallics to N‐(α‐Ketoacyl)‐trans‐2,5‐bis(methoxymethoxymethyl)pyrrolidine.
Authors: KAWANAMI Y. , FUJITA I. , OGAWA S. , KATSUKI T. 
Published: May 2016

AbstractThe N‐(1,2‐dioxophenethyl)pyrrolidine (I) is reductively methylated with the methylmetallic reagents (II) to give mixtures of the diastereomeric acyloins (III) and (IV).
ChemInform Abstract: Benzyne‐Oxazole Cycloadducts: Isolation and Retro‐Diels‐Alder Reactions.
Authors: WHITNEY S. E. , WINTERS M. , RICKBORN B. 
Published: May 2016

AbstractDiels‐Alder reaction of benzyne (II), generated by oxidation of the aminobenzotriazole (I) with lead tetraacetate, with the oxazoles (III), yields the cycloadducts (IV).
ChemInform Abstract: Synthesis and Pharmacological Screening of a New Series of 3‐(4‐Antipyryl)‐2‐arylthiazolidin‐4‐ones.
Authors: AL‐KHAMEES H. A. , BAYOMI S. M. , KANDIL H. A. , EL‐TAHIR K. E. H. 
Published: May 2016

AbstractThe title compounds are evaluated for antinociceptive and spasmolytic activity.
ChemInform Abstract: Preparation and Antiarthritic Activity of New 1,5‐Diaryl‐3‐alkylthio‐1H‐1,2,4‐triazoles and Corresponding Sulfoxides and Sulfones.
Authors: SZILAGYI G. , SOMORAI T. , BOZO E. , LANGO J. , NAGY G. , REITER J. , JANAKY J. , ANDRASI F. 
Published: May 2016

Abstract104 Triazoles of type (IV) or (VI) are synthesized and evaluated as anti‐inflammatory agents in the rat adjuvant‐induced arthritis assay.
ChemInform Abstract: Synthesis of 6H‐Pyrrolo(1,2‐c)(1,2,3)triazoles and 5H‐Pyrrolo(1,2‐d)tetrazoles: Alkylation and Acylation of the Monoanions.
Authors: DULCERE J.‐P. , TAWIL M. , SANTELLI M. 
Published: May 2016

AbstractThermal cyclization of the 1‐azido‐2‐penten‐4‐yne (III) leads to the formation of the triazole (IV) which is methylated to give the derivatives (VI) and (VII) via the corresponding anion.
ChemInform Abstract: Alkylation of 1,3‐Dithiane 1,1,3,3‐Tetroxide Derivatives.
Authors: BAZAVOVA I. M. , ESIPENKO A. N. , NEPLYUEV V. M. , LOZINSKII M. O. 
Published: May 2016

AbstractAlkylation of the dithiane tetroxides (I) gives the monoalkylated (V), (VII), dialkylated (V), or spirocyclic compounds (VIII) depending on the molar ratio of the reactants and the reaction conditions.