bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sharing a Personal Trainer: Personal and Social Benefits of Individualized, Small-Group Training
Authors: Wayment Heidi A. , McDonald Rachael L. 
Published: March 2017

Abstract
Wayment, HA and McDonald, RL. Sharing a personal trainer: personal and social benefits of individualized, small-group training. J Strength Cond Res 31(11): 3137–3145, 2017—We examined a novel personal fitness training program that combines personal training principles in a small-group training environment. In a typical training session, exercisers warm-up together but receive individualized training for 50 minutes with 1–5 other adults who range in age, exercise experience, and goals for participation. Study participants were 98 regularly exercising adult members of a fitness studio in the southwestern United States (64 women and 32 men), aged 19–78 years (mean, 46.52 years; SD = 14.15). Average membership time was 2 years (range, 1–75 months; mean, 23.54 months; SD = 20.10). In collaboration with the program directors, we developed a scale to assess satisfaction with key features of this unique training program. Participants completed an online survey in Fall 2015. Hypotheses were tested with a serial mediator model (model 6) using the SPSS PROCESS module. In support of the basic tenets of self-determination theory, satisfaction with small-group, individualized training supported basic psychological needs, which in turn were associated with greater autonomous exercise motivation and life satisfaction. Satisfaction with this unique training method was also associated with greater exercise self-efficacy. Autonomous exercise motivation was associated with both exercise self-efficacy and greater self-reported health and energy. Discussion focuses on why exercise programs that foster a sense of social belonging (in addition to motivation and efficacy) may be helpful for successful adherence to an exercise program.
Thyroid function in children and adolescents with Hashimoto's thyroiditis after l-thyroxine discontinuation
Authors: Radetti Giorgio , Salerno Mariacarolina , Guzzetti Chiara , Cappa Marco , Corrias Andrea , Cassio Alessandra , Cesaretti Graziano , Gastaldi Roberto , Rotondi Mario , Lupi Fiorenzo , Fanolla Antonio , Weber Giovanna , Loche Sandro 
Published: March 2017

Objective
Thyroid function may recover in patients with Hashimoto’s thyroiditis (HT).

Design
To investigate thyroid function and the need to resume l-thyroxine treatment after its discontinuation.

Setting
Nine Italian pediatric endocrinology centers.

Patients
148 children and adolescents (25 m and 123 f) with HT on treatment with l-thyroxine for at least one year.

Intervention and main outcome measure
Treatment was discontinued in all patients, and serum TSH and fT4 concentrations were measured at the time of treatment discontinuation and then after 2, 6, 12 and 24 months. Therapy with l-thyroxine was re-instituted when TSH rose >10 U/L and/or fT4 was below the normal range. The patients were followed up when TSH concentrations were between 5 and 10 U/L and fT4 was in the normal range.

Results
At baseline, TSH was in the normal range in 139 patients, and was between 5 and 10 U/L in 9 patients. Treatment was re-instituted after 2 months in 37 (25.5%) patients, after 6 months in 13 patients (6.99%), after 12 months in 12 patients (8.6%), and after 24 months in an additional 3 patients (3.1%). At 24 months, 34 patients (34.3%) still required no treatment. TSH concentration >10 U/L at the time of diagnosis was the only predictive factor for the deterioration of thyroid function after l-thyroxine discontinuation.

Conclusions
This study confirms that not all children with HT need life-long therapy with l-thyroxine, and the discontinuation of treatment in patients with a TSH level <10 U/L at the time of diagnosis should be considered.
GeneImp: Fast Imputation to Large Reference Panels Using Genotype Likelihoods from Ultralow Coverage Sequencing
Authors: Spiliopoulou Athina , Colombo Marco , Orchard Peter , Agakov Felix , McKeigue Paul 
Published: March 2017

Abstract
We address the task of genotype imputation to a dense reference panel given genotype likelihoods computed from ultralow coverage sequencing as inputs. In this setting, the data have a high-level of missingness or uncertainty, and are thus more amenable to a probabilistic representation. Most existing imputation algorithms are not well suited for this situation, as they rely on prephasing for computational efficiency, and, without definite genotype calls, the prephasing task becomes computationally expensive. We describe GeneImp, a program for genotype imputation that does not require prephasing and is computationally tractable for whole-genome imputation. GeneImp does not explicitly model recombination, instead it capitalizes on the existence of large reference panels—comprising thousands of reference haplotypes—and assumes that the reference haplotypes can adequately represent the target haplotypes over short regions unaltered. We validate GeneImp based on data from ultralow coverage sequencing (0.5×), and compare its performance to the most recent version of BEAGLE that can perform this task. We show that GeneImp achieves imputation quality very close to that of BEAGLE, using one to two orders of magnitude less time, without an increase in memory complexity. Therefore, GeneImp is the first practical choice for whole-genome imputation to a dense reference panel when prephasing cannot be applied, for instance, in datasets produced via ultralow coverage sequencing. A related future application for GeneImp is whole-genome imputation based on the off-target reads from deep whole-exome sequencing.
Torcer el remolino de injusticia: teatro, campesinado peruano y denuncia social en Víctor Zavala
Authors: Gallardo-Saborido Emilio J. 
Published: March 2017

O teatro do peruano Víctor Zavala Cataño (Huamantanga, 1932) oferece uma proposta de reivindicação do campesinato peruano sustentada por uma leitura marxista da realidade andina. Através da análise das peças do seu volume seminal Teatro campesino (1969) e do posterior Teatro popular I (1984), esta contribuição indaga nos traços ideológicos e artísticos destes textos. Neste sentido destaca, de um lado, a representação do camponês indígena como sujeito político autónomo, disposto a reagir de um modo revolucionário aos opressores. De outro, o trabalho de Zavala como aclimatador dos ensinamentos de Bertolt Brecht ao contexto dos Andes peruanos para assim elaborar seu discurso artístico e político. Deste modo, suas criações se inserem na tradição literária indigenista peruana, mas contam com a particularidade de se articular principalmente através do teatro. A relevância que o camponês indígena obtém nas obras de Zavala rompe com o passado e ao mesmo tempo abre uma trilha que nos anos seguintes percorrerão em profusão outros autores e grupos teatrais.
Idle No More: del reconocimiento al resurgimiento indígena en Canadá
Authors: Altamirano Isabel , Castro-Rea Julian 
Published: March 2017

Neste artigo se pretende analizar a constituição do movimento indígena No Más Pasividad de Canadá, as ideias que o sustentam, assim como a evolução das práticas políticas do movimento indígena dos anos 1960 à atualidade. Se optou por combinar o conceito de campo de Bourdieu e de colonialismo de colonos para entender como o contexto indigenista e o tipo de recursos ou capitais que os distintos atores disputavam determinam as limitações do reconhecimento liberal. Se defende que o movimento No Más Passividad não apenas se opõe ao reconhecimento liberal da indianidade e dos direitos indígenas, mas também busca reclamar e reconstituir espaços indígenas autónomos do Estado, assim como redefinir a discussão sobre os direitos indígenas.
Keringő mikroRNS-ek az endokrin daganatok diagnosztikájában
Authors: Decmann Ábel , Perge Pál , Nagy Zoltán , Butz Henriett , Patócs Attila , Igaz Péter 
Published: March 2017

Abstract: MicroRNAs (miRNA, miR) are short – 19–25 nucleotide long – single stranded (in their mature form), non-coding RNA molecules that regulate gene expression mostly at the posttranscriptional level. microRNAs are involved in the regulation of various physiological processes such as cell differentiation and proliferation, development, haematopoesis, cell death, while their aberrant expression is observed in numerous diseases, like autoimmune disorders, inflammations, vascular diseases or tumorigenesis. microRNAs are expressed in a tissue specific fashion. Beyond their appearance in tissues, they can be found in body fluids as well. microRNAs are present in blood, mother milk, semen, saliva, urine, etc. MicroRNAs in body fluids, especially the blood-borne circulating microRNAs can be exploited as minimally invasive biomarkers of tumor diagnosis. The number of endocrine tumor-associated circulating microRNA alterations is relatively low, mostly described for papillary thyroid cancer, adrenocortical cancer, ovarian and neuroendocrine tumors. As the histological diagnosis including the establishment of malignancy of some of these neoplasms is difficult, studies on circulating microRNAs might have great perspectives. Orv. Hetil., 2017, 158(13), 483–490.
Positive thinking and physical activity motivation for one individual with multiple sclerosis: A qualitative case-study
Authors: Hall-McMaster Samuel M. , Treharne Gareth J. , Smith Catherine M. 
Published: March 2017

Regular physical activity (PA) is known to benefit individuals with multiple sclerosis (MS) but people with MS tend to do less PA than the general population. Thought processes such as positive thinking may help to explain PA motivation among individuals with MS. The present study investigated thoughts about PA motivation in one man with MS (aged 70 years; pseudonym Norman). We asked Norman to think aloud while completing standardised measures of PA, stages of change, self-efficacy and in response to planned and spontaneous questions. The data were subjected to inductive thematic analysis and two major themes were formulated: positive thinking as Norman’s way to fight against MS; and goals give a positive purpose to Norman’s engagement in PA. Theme one consisted of three subthemes: coping with MS by choosing to think positively; using positivity to maintain control; and using PA to think positively. Theme two consisted of two subthemes: viewing PA as a necessity for goal achievement; and goals providing determination. Norman’s case has implications for enhancing future physiotherapy interventions. In particular, addressing positive thinking and purposeful goal setting may help physiotherapists to increase PA motivation in individuals with MS and thereby encourage more regular engagement in PA.
Te Vaerua Community Rehabilitation Service: A Participation Action Research study of community based rehabilitation in the Cook Islands
Authors: Washbourn Rebecca , Levack William M. M. , Graham Fiona , Currey Nandika 
Published: March 2017

Community based rehabilitation (CBR) is a World Health Organisation initiative to support people with disabilities to attain maximal life participation through locally based programmes. Te Vaerua Community Rehabilitation Team (Te Vaerua) is a provider of CBR in the Cook Islands. This study used a Participatory Action Research (PAR) framework to explore cultural values, motivations for and provision of rehabilitation by Te Vaerua in the Cook Islands. Data was collected through focus groups, interviews, participant observation, and an emergent process of action cycles with local rehabilitation stakeholders. Three key themes were identified: 1) rehabilitation is available, 2) rehabilitation has heart, and 3) rehabilitation gives hope. These themes have an overarching concept of ‘ko te iti tangata te mea maata’ – that people are the most important thing. Rehabilitation was seen as central to broader social objectives to strengthen families, empower Cook Islands citizens, support people to remain in the Cook Islands, and to provide opportunities for people to give back to their communities. The study concluded that strong relationships between providers and the local community are essential to successfully implement both PAR and CBR.
Potential for identifying plant-based toxins on San hunter-gatherer arrowheads
Authors: Wooding Madelien , Bradfield Justin , Maharaj Vinesh , Koot Dwayne , Wadley Lyn , Prinsloo Linda , Lombard Marlize 
Published: March 2017

The antiquity of the use of hunting poisons has received much attention in recent years. In this paper we present the results of a pilot study designed to detect the presence of organic compounds, typically of less than 1200 Da, from poisonous plants that may have been used as hunting poisons in the past. We used ultra-performance liquid chromatography connected to a Synapt G2 high-resolution MS-QTOF mass spectrometer (UPLC-QTOF-MS) to provisionally identify plant-based toxins present in (1) extracts of fresh plant material, (2) a blind control recipe consisting of three plant ingredients and (3) a Hei||om arrow poison of unknown ingredients. Although not all expected toxic compounds were identified, those that were identified compared favourably with those reported in the literature and confirmed through databases, specifically the Dictionary of Natural Products and ChemSpider. MS/MS fragmentation patterns and accurate mass were used for tentative identification of compounds because archaeological residues usually contain insufficient material for unambiguous identification using nuclear magnetic resonance. We highlight the potential of this method for accurately identifying plant-based toxins present on archaeological artefacts and unique (albeit non-toxic) chemical markers that may allow one to infer the presence of toxic plant ingredients in arrow poisons. Any chemical study of archaeological material should consider the unique environmental degradative factors and be sensitive to the oxidative by-products of toxic compounds.

Significance:

Methodology is presented for the identification of ancient plant-based arrow poisons.
Guidelines for analysis on measuring interrater reliability of nursing outcome classification
Authors: Nurjannah Intansari , Siwi Sri Marga 
Published: March 2017

Indicators in nursing outcome classification (NOC) need to be tested for their validity and reliability. One method to measure reliability of NOC is by using interrater reliability. Kappa and percent agreement are common statistic analytical methods to be used together in measuring interrater reliability of an instrument. The reason for using these two methods at the same time is that those statistic analytical methods have easy reliability interpretation. Two possible conflicts may possibly emerge when there are asynchronies between kappa value and percent agreement. This article is aimed to provide guidance when a researcher faces these two possible conflicts. This guidance is referring to interrater reliability measurement using two raters.
The spectrum of MEFV gene mutations and genotype-phenotype correlation in Egyptian patients with familial Mediterranean fever
Authors: Ali Fahmy T. , Elhady Mostafa M. , Abbas Hanan H. , Mandouh AbdAllah Y. 
Published: March 2017

Background: Familial Mediterranean fever (FMF) is an autosomal recessive disease mainly affecting subjects of the Mediterranean origin. It is an auto-inflammatory periodic disorder that is caused by mutations in the Mediterranean fever gene (MEFV) located on chromosome 16.Methods: The current study was designed to assess the prevalence and frequency of different MEFV gene mutations among 104 FMF clinically diagnosed Egyptian patients and to evaluate the change extent in the values of some biochemical markers (ESR, CRP, Fibrinogen-C, SAA and IL1) in different participants with different FMF severity scores.Results: According to allele status 28 patients (27%) were homozygous mutation carriers, 38 (36.5%) were with compound heterozygous mutations and 38 (36.5%) were identified as heterozygous for one of the studied mutations. Of the studied mutations, M694I, E148Q, V726A, M680I, and M694V accounted for 28.1%, 26.8%, 16.9%, and 11.3% of mutations respectively. The R761H and P369S mutations were rarely encountered mutations (1.4%). The clinical features with M694I were associated with more severe clinical course. There is a drastic elevation in the levels of estimated parameters as their levels were increased as long as the severity of the disease increased.Conclusions: The diagnosis of FMF cannot be performed on the basis of genetic testing or clinical criteria alone. So, we recommended the combination between clinical and molecular profiling for FMF diagnosis and scoring.
Probable mental illnesses among tea plantation workers in Anaimalai, Tamil Nadu, South India
Authors: G. S. Ashwini , Ramesh Naveen , C. J. Navya , Joy Jino , Oommen Abel Thomas , Singh Jyoti 
Published: March 2017

Background: The prevalence of mental illnesses among industrial workers is found to be 14% - 51%, which is more than that in the general population. Individual’s psychosocial functioning has an impact on the work efficiency. The objective of the study was to assess the prevalence of probable mental illness and its associated factors among workers in selected tea estates in South India. Methods: A cross sectional study was done in two tea estates in Tamil Nadu from March to May, 2012. The General Health Questionnaire (GHQ) 28 was used to screen for probable mental illness. Sociodemographic details, work profile and associated risk factors were also elicited. Results: Among the 400 subjects interviewed, 75.5% were females. The mean age was 43.21 (±7.47) years and the mean work experience was 21.38 (±9.31) years. In our study 12.8% subjects screened positive for probable mental illness and 1%, 1%, 0.2% and 1.5% screened positive in the domains somatic symptoms, anxiety/insomnia, social dysfunction and severe depression respectively. Workers who screened positive for probable mental illness had availed significantly greater duration of leave in the previous year. There was no significant association of mental illness with age, gender, marital status, substance abuse, designation, co-morbidity and stressful life events. Conclusions: There is a need to screen individuals in different occupation for probable mental illness and those screened positive need evaluation by a psychiatrist. There is also a need to explore associated factors in order to improve one’s health and work efficiency.
Assessment of Facility based newborn care at various health care facilities in Rajkot district
Authors: Oza Jasmin R. , Jogia Ashutosh D. , Kanabar Bhavesh R. , Thakrar Dhara V. 
Published: March 2017

Background: India carries the single largest share (around 25-30%) of neonatal deaths in the world. It has been estimated that about 70% of neonatal deaths could be prevented if proven interventions are implemented effectively with high coverage.Methods: A cross-sectional observational study was conducted at various health facilities of Rajkot district where facility based newborn care are created as per the guidelines under NRHM. It was conducted during August 2013 to October, 2013. The data entry was done in Microsoft Office Excel 2007 and analyzed in Epi info software from CDC Atlanta. Results: This study included total 32 health facilities including 10 Primary Health Centers (PHC) (24X7), 15 Community Health Centers (CHC), 5 Sub District Hospitals (SDH), one District Hospital (DH) and one Medical College (MC). There are a total of 36 facilities of different level available in government set up for newborn care starting from NBCC to SNCU. All (100%) of the health centers visited were equipped with NBCC for newborn care, while NBSU and SNCU for newborn care were created at only 2 (6.2%) centers respectively. Only 2 out of 10 PHC had all required equipments for NBCC. All the required equipments were available at 3 CHCs out of total 15 CHCs. All the SDH were having adequate equipment for NBCC except resuscitator & separate Digital Thermometer were not available at 2 SDH. At DH, except for Digital thermometer, all equipments were adequate. Only 1 SDH has been established for NBSU and it did not have adequate no. of radiant warmer and resuscitator. DH is lacking in all the required equipment for SNCU except for resuscitator (250 ml) and refrigerator. Out of total 101 health personnel, 68 (67.3%) have been trained for NSSK. From total 68 trained health personnel, 12 (17.7%) got the score above the cut off for resuscitation skill. Out of the trained respondents, 29 (42.7%) acquired score above cut off for routine care.Conclusion: All the PHCs, CHCs, SDHs and DH were deficient in equipments. NBSU was created in only one SDH. SNBU was created at DH and MC, but equipments were not sufficient at both centers. Health care providers involved in facility based newborn care units had poor knowledge regarding routine newborn care and also not properly trained in resuscitation.
A Case History – A New Stimulation Technique Enables Sustained Production Enhancement in Mature Lenticular Reservoir
Authors: Precupanu L. , Mocanu A. , Abbott J. , Dragomir A. , Sarbu N. I. , Calin C. I. 
Published: March 2017

Abstract
Romania is a key pioneer in oil and gas industry with a history of more than 150 years'experience. Many of the oil fields discovered in the early days are still being produced. Extending the production life of mature fields presents a variety of challenges including low reservoir pressure, high water cut, limited well data, aging completions and bypassed pay. The target field is a mature oil field situated in the heart of Romania that has been operated since the 1960s and exhibits many of the aforementioned issues. This paper describes the reservoir, exploitation difficulties and new techniques applied to overcome the key challenges to effectively producing this aging asset.
Production enhancement in mature assets require new approaches that can address key challenges and risks associated with the reservoir and completion age. Application of conventional can easily lead to failures including ineffective stimulation, completion failure, screen-out, and increased water cut, all causing difficulties to put wells back in production and resulting in disappointing results. In mature fields, a different approach is required.
This paper details first time application of the flow channel hydraulic stimulation in one of the wells in the field, describing the importance of well candidate selection phase, engineered design, execution, and evaluation. The applied channel hydraulic stimulation combines geomechanical modeling with intermittent proppant pumping and degradable fibers to obtain heterogeneous placement of proppant within the fracture. A post job production evaluation compares the production after the conventional treatments versus post flow channel hydraulic stimulation job. The results for all conventional hydraulic stimulation treatments show a steep production decline rate, while the positive impact of channel hydraulic stimulation is apparent resulting in higher initial production and an overall slower production decline.
The productive reservoirs besides of low reservoir pressure, are characterized by an increased degree of lamination. The target interval is usually described by a sequence of marls and lenticular streaks of sandstone and shaly-marly sandstone. Conventional hydraulic stimulation treatments have had a marginal effect in this reservoir. Due to the variable lithology, gained limited connection through conventional ways of stimulation and/or perforation end up in quick depletion and production decrease. Channel hydraulic stimulation was applied for the first time in this field and may now be considered to be an efficient way of enhancing production in this and similar reservoirs.