bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polypharmacy in Older Adults: The Hazard of Hospitalization and Mortality is Mediated by Potentially Inappropriate Prescriptions, Findings From the Moli-sani Study
Authors: Costanzo Simona , Di Castelnuovo Augusto , Panzera Teresa , De Curtis Amalia , Falciglia Stefania , Persichillo Mariarosaria , Cerletti Chiara , Donati Maria Benedetta , de Gaetano Giovanni , Iacoviello Licia ,   the Moli-sani Investigators
Published: October 2024

ObjectivesWe evaluated the impact of polypharmacy on the health of community-dwelling older adults.MethodsWe prospectively analyzed 5,631 individuals from the Moli-sani study (51% men, aged ≥65 years, recruitment 2005–2010, follow-up 2005–2020). Exposure was categorized as chronic polypharmacy therapy (C-PT; ≥5 therapeutic groups and &gt;2 defined daily doses (DDDs)) or non-chronic polypharmacy therapy (NC-PT; polypharmacy but ≤2 DDDs). Hospitalization and mortality were the main outcomes. The mediating role of potentially inappropriate prescriptions (PIP) was examined.ResultsCompared to individuals not on polypharmacy, those in NC-PT and C-PT had higher hazards of mortality [21% (95% CI 7%–37%) and 30% (16%–46%), respectively] and hospitalization [39% (28%–51%) and 61% (49%–75%), respectively]. Similar results were found for cardiovascular outcomes. PIP mediated the association between polypharmacy and outcomes, with mediation effects ranging from 13.6% for mortality to 6.0% for hospitalization. Older adults without multimorbidity experienced the same harm from multiple medications as those with multimorbidity.ConclusionPolypharmacy is associated with a higher hazard of mortality and hospitalization, with PIP playing an important role. Addressing “medication without harm” requires assessing the appropriateness of drug prescriptions and monitoring for adverse effects.
Principais causas de morte materna no estado do Acre no período compreendido entre 2018 a 2024
Authors: Albuquerque Ana Sara Camelo de , Anjos Raquel Fabricia Verçosa dos , Batista Regina Maria Barbosa , Costa Ruth Silva Lima da 
Published: October 2024

A mortalidade materna refere-se ao óbito de uma mulher durante a gravidez, parto ou até 42 dias após o término da gestação, devido às complicações relacionadas ao processo gestacional. Trata-se de um indicador importante de saúde pública, refletindo a qualidade dos serviços de saúde e o acesso ao cuidado durante a gestação. Objetivou-se demostrar as principais causas de morte materna no estado do Acre no período compreendido 2018 a 2024. Trata-se de um estudo transversal, retrospectivo, exploratório, de abordagem quantitativa, com coleta de dados secundários, extraídos no site do Departamento de Informática do SUS – DATASUS, tabulados a partir do TABNET. Entre 2018 e 2023, o Acre registrou 48 óbitos maternos, com a maioria ocorrendo em Rio Branco (45,8%). O ano de 2021 teve o maior número de casos (15 óbitos, 31,3%), possivelmente devido à pandemia de COVID-19. A faixa etária mais afetada foi de 20 a 29 anos (45,8%), e a cor predominante foi parda (64,6%). A maioria dos óbitos ocorreu em ambiente hospitalar (90%) e no puerpério (50%). A principal causa foi "Morte materna obstétrica direta" (75%), seguida por doenças infecciosas e parasitárias (18,8%). Apesar da redução dos óbitos maternos no Acre, a mortalidade ainda é um desafio, especialmente no puerpério. A necessidade de melhorar o acesso aos serviços de saúde e estratégias de prevenção é crucial, assim como o monitoramento contínuo para informar políticas pública.
«Не покорюсь!» Жизнь и творчество поэтессы Русского Зарубежья Марианны Колосовой
Authors: А.В. Окороков 
Published: October 2024

В статье рассматривается творчество русских эмигрантских поэтов в 1930-х – 1940-х годах в Китае как часть русской литературы XX века. Приводятся сведения о жизни и деятельности популярной в то время национальной поэтессы – Марианны Колосовой.
Russian emigrant poets of the 1930s - 1940s in China, as part of the Russian literature of the XX century, are considered in the article. The article provides information about the life and work of Marianna Kolosova, a popular national poetess at that time.
Северный Ледовитый океан. Русские географические названия как объекты нематериального культурного наследия
Authors: А.И. Ельчанинов 
Published: October 2024

Северный Ледовитый океан всегда притягивал внимание многих государств. Границы этих государств определены и закреплены законодательством. В иностранных секторах Северного Ледовитого океана имеются русские географические названия в честь российских первооткрывателей. Русские географические названия приводятся в алфавитном порядке. Представлена также карта-схема с этими названиями.
The article was written as part of the state assignment for 2024. The Arctic Ocean has always attracted the attention of many states. The borders of these states are defined and secured by law. Foreign sectors of the Arctic Ocean have Russian geographical names in honor of Russian discoverers. Russian geographical names are listed in alphabetical order. A schematic map with these names is also presented.
Заметка о представителях рода Флекенштейн
Authors: Ю.С. Избачков , К.Е. Рыбак 
Published: October 2024

Происхождение одного из Генеральных секретарей ЦК КПСС, фактического руководителя страны Юрия Владимировича Андропова до сих пор окружено легендами и историческими спекуляциями. В статье раскрываются вопросы, связанные с удочерением его матери Евгении временным московским купцом Карлом Флекенштейном и его женой Евдокией Михайловной, урожд. Сидориной. Анализируя информацию, сопутствующую нахождению подкидыша, авторы статьи подходят к предположению, что, возможно, Евгения была дочерью кого-то из окружения удочерителей: либо была взята Флекенштейнами в свою семью по причине смерти матери Евгении, либо отказе матери от дочери.
The origin of one of the General Secretaries of the Central Committee of the Communist Party of the USSR, the de facto leader of the country, Yuri Vladimirovich Andropov, is still surrounded by legends and historical speculation. The article reveals issues related to the adoption of his mother Evgenia by the temporary Moscow merchant Karl Fleckenstein and his wife Evdokia Mikhailovna, born. Sidorina. Analyzing the information accompanying the discovery of the foundling, the authors of the article come to the assumption that perhaps Evgenia was the daughter of someone from the adoptive circle, or was taken by the Fleckensteins into their family due to the death of Evgenia’s mother or the mother’s abandonment of her daughter.
Дифференциальная диагностика акантолитической пузырчатки
Authors: Г.Н. Акишева , Г.Р. Батпенова , З.С. Джетписбаева 
Published: October 2024

Вульгарная пузырчатка, листовидная пузырчатка, паранеопластическая пузырчатка, лекарственная пузырчатка, IgA-пузырчатка относятся к группе заболеваний, которые представляют собой аутоиммунные буллезные дерматозы. Эти состояния характеризуются образованием везикул и пузырей на коже и слизистых оболочках из-за аутоантител, нацеленных на десмосомальные белки, которые приводят к потере клеточной адгезии внутри эпидермиса. Диагностика форм пузырчатки может быть сложной из-за потенциального совпадения клинических особенностей и серьезных последствий позднего или неправильного диагноза. Дифференциальная диагностика в сочетании с эпидемиологией, клинической оценкой и лабораторным исследованием, включая гистопатологию, прямую/непрямую иммунофлюоресценцию и иммуноферментный анализ, необходима для точной диагностики и классификации пузырчатки, что позволяет обеспечить соответствующее ведение и лечение для минимизации заболеваемости и смертности от пузырных дерматозов.
Pemphigus vulgaris, pemphigus foliaceus, paraneoplastic pemphigus, drug-induced pemphigus, IgA pemphigus refer to a family of pemphigus diseases, which are autoimmune bullous dermatoses. These conditions are characterized by the formation of vesicles and bullae on the skin and mucous membranes due to autoantibodies targeting desmosomal proteins, which lead to loss of cellular adhesion within the epidermis. Diagnosis of pemphigus diseases can be challenging due to the potential for overlapping clinical features and the serious consequences of late or incorrect diagnosis. Differential diagnosis in combination with epidemiology, clinical evaluation and laboratory testing including histopathology, direct/indirect immunofluorescence and enzyme immunoassay is necessary for accurate diagnosis and classification of pemphigus diseases, allowing for appropriate management and treatment to minimize morbidity and mortality from bullous dermatoses.
Uji Efektifitas Antibakteri Sabun Cair Dari Estrak Daun Jarum Tujuh Bilah (Pereskia Bleo) Terhadap Bakteri Staphylococcus Aureus Fakultas Kedokteran Universitas Prima Indonesia
Authors: Hanifa Driantsani Qonita , Fadillah Qori , Wahyuni Sri 
Published: October 2024

Kebersihan kulit sangat penting untuk mencegah infeksi yang disebabkan oleh mikroorganisme, terutama bakteri seperti Staphylococcus aureus. Kulit berfungsi sebagai pelindung tubuh dan dapat menjadi pintu masuk bagi bakteri penyebab penyakit. Penggunaan sabun, khususnya sabun cair dan sabun antibakteri, semakin populer di masyarakat karena efektif dalam membersihkan kulit dan mencegah infeksi. Namun, ada kecenderungan untuk mencari alternatif bahan alami sebagai pengganti produk berbahan kimia sintetik. Salah satu tanaman yang memiliki potensi antibakteri adalah Daun Jarum Tujuh Bilah (Pereskia bleo). Penelitian ini bertujuan untuk mengeksplorasi manfaat ekstrak etanol dari daun tersebut melalui skrining fitokimia dan uji aktivitas antibakteri, sejalan dengan tren pengobatan tradisional yang semakin diminati sebagai solusi alami. Hasil penelitian diharapkan dapat memberikan wawasan mengenai potensi Daun Jarum Tujuh Bilah (Pereskia bleo) sebagai antibakteri alami untuk mendukung kesehatan kulit.
EXTRACTION OF A RIGHT UPPER SECOND MOLAR WITH PERIAPICAL LESION: CASE REPORT
Authors: Guimarães Sampaio Trajano Dos Santos Pedro , Cavalcanti de Lima Félix Lucas , Alves Sarmento José Henrique , Camillo Veras Juliana , Coelho Travassos Rosana Maria , Perez Leyva Ataíde Juliana , Coelho de Ataíde Filho Ailton , Barreto Silva Luciano 
Published: October 2024

ABSTRACT

Objective: The objective of this case report article is to report the extraction of a second upper right molar in which there was a large periapical lesion. Methodology: During the construction of this case report, it was necessary to use the work produced by Yin (2001) as a basis, because his study teaches how the structure of a case report article should be, as well as the methodology for searching for articles, course completion, master's and doctoral papers, which are included in this report, enriching it with proven information and scientific basis, improving this study. In order to find works related to the topic addressed and contribute with more information, searches were carried out using the following keywords: Exodontia; Periapical Lesion; Endodontics. In addition to the keywords used to acquire information relevant to the topic, searches were made in the following databases: PUBMED Central, BVS/BIREME, Scielo, Web of Science, PROSPERO in conjunction with Google Academy. Results: During the tooth removal process, there was great difficulty because it was extremely worn, fragmenting every time they tried to remove it with forceps, even the crown fragmenting. Conclusion: Odontosection was extremely useful in removing this tooth. tooth mainly because it fragments naturally due to its conditions and that after extraction, the presence of a large periapical lesion was seen, which explains the pain the patient felt in the tooth before extraction.
Enhancing Productivity and Alleviating Fatigue in General Purpose Machining by SMART Approach
Authors: Sushil V. Deshpande  , Ramkisan S. Pawar  , Ashok J. Keche  , Sachin S Yadav  
Published: October 2024

In the realm of general lathe machining, the objective of improving output while decreasing worker fatigue is critical. An emphasis is placed on factors contributing to fatigue such as prolonged standing, repetitive motions particularly in the measuring concern, interruptions in operation, continuous targeted stress in linking of manufacturing-measurement and achievement of target dimensions, and lack of on-machine back guidance. This increases cycle time, raises rejection rates and impacts on product quality. The SMART with a simplified developed algorithm technique promotes fatigue relief and increased productivity by allowing for automated inline measuring of workpieces to get live status and offering continuous advice for process completion. It consists of an online communication display that allows the operator to refer to the live work dimensions. A sensor data of work piece dimensions is processed through communication system and displayed for operator perusal and action. The wholistic approach of the method reveals strengths such as, notable 26% improvement in manufacturing time, a substantial 75% reduction in defects per batch, 100% comprehensive guidance, 80% reduction in engagement per batch, 40% increased production, reduction in repetitive motions by 25%, 100% reduced rejection rates. Likewise so many factors resulting in a positive impact on operational productivity and output excellence.
Keywords: Continual feedback system, inspection elimination, fatigue-free, quality improvement, cycle time, rejection rates
Increasing transparency of computer-aided detection impairs decision-making in visual search
Authors: Kunar Melina A. , Montana Giovanni , Watson Derrick G. 
Published: October 2024

AbstractRecent developments in artificial intelligence (AI) have led to changes in healthcare. Government and regulatory bodies have advocated the need for transparency in AI systems with recommendations to provide users with more details about AI accuracy and how AI systems work. However, increased transparency could lead to negative outcomes if humans become overreliant on the technology. This study investigated how changes in AI transparency affected human decision-making in a medical-screening visual search task. Transparency was manipulated by either giving or withholding knowledge about the accuracy of an ‘AI system’. We tested performance in seven simulated lab mammography tasks, in which observers searched for a cancer which could be correctly or incorrectly flagged by computer-aided detection (CAD) ‘AI prompts’. Across tasks, the CAD systems varied in accuracy. In the ‘transparent’ condition, participants were told the accuracy of the CAD system, in the ‘not transparent’ condition, they were not. The results showed that increasing CAD transparency impaired task performance, producing an increase in false alarms, decreased sensitivity, an increase in recall rate, and a decrease in positive predictive value. Along with increasing investment in AI, this research shows that it is important to investigate how transparency of AI systems affect human decision-making. Increased transparency may lead to overtrust in AI systems, which can impact clinical outcomes.
El Grupo Focal como Técnica Terapéutica y de Recabación de Datos en EstudiantesSobrevivientes de Abuso Sexual
Authors: Quevedo Fuentes Martha Patricia , Chupín Torreblanca Carlos 
Published: October 2024

Se describe la aplicación de la Entrevista de Grupo Focal con el objetivo de utilizarla como técnica terapéutica y de recabación de datos en estudiantes de licenciatura, sobrevivientes de abuso sexual. El enfoque del presente estudio es cualitativo, de tipo fenomenológico, de diseño descriptivo y de corte transversal. Participaron 20 estudiantes, de los cuales 17 fueron mujeres y tres hombres. Instrumentos utilizados: se aplicó el test proyectivo del Dibujo de la Figura Humana, con la finalidad de seleccionar a la población que experimentó abuso sexual; asimismo. se utilizó el Oficio de Consentimiento Informado con la intención de garantizar la parte ética de la investigación y posteriormente se empleó la Entrevista de Grupo Focal, donde se recabaron datos importantes sobre el fenómeno de abuso sexual y, además, sirvió como técnica terapéutica ya que funcionó como efecto dominó, todos los participantes expresaron su experiencia de abuso, incluso, para la mayoría de ellos, era la primera vez que lo externaban. Los resultados encontrados fueron: recabación de la edad en la que sufrieron el abuso; el tipo de abuso; Lugar donde se perpetuó el abuso; relación con el abusador y Estrategia utilizada por el agresor para convencer. Se propone la aplicación de esta técnica en los centros educativos, con el fin de crear espacios donde los estudiantes puedan externar experiencias dolorosas como las de abuso sexual.
Catalytic Pyrolysis of Malaysia Tea Waste over Molybdenum Modified Zeolite for Bio-Oil Production
Authors: Haidir Muhammad Hadif , Balasundram Vekes , Ibrahim Norazana , Isha Ruzinah , Gopakumar Suchithra Thangalazhy , Bindar Yazid , Le Kim Hoang Pham , Suan Shi , Suneerat Fukuda 
Published: October 2024

In the current era, the increasing population has raised energy needs and heavy reliance on fossil fuels has led to greenhouse gas emissions. The abundance of biomass in Malaysia, such as tea waste, is poorly managed, contributing to environmental issues. Thus, the main goal of this research is to investigate the influence of Molybdenum-modified Hydrogen-exchanged Zeolite Socony Mobil-5 (Mo-HZSM-5) on the pyrolysis of Malaysian tea waste at varied temperatures from 400 to 600 C with 50 C intervals to produce bio-oil via fixed-bed reactor. The catalyst-to-tea waste mass ratio was constant at 1.1 for all the investigated samples. Among the investigated samples, the highest bio-oil produced was at 600 C (13.97 wt. percent). Surprisingly, adding Mo-HZSM-5 did not increase the bio-oil yield, which is 4.50 wt. percent at 600 C. However, the composition of hydrocarbons in bio-oil from catalytic pyrolysis is higher (18.16 percent) than non-catalytic (9.73 percent) at 500 C. Furthermore, with Mo-HZSM-5, the total oxygenated compound presences are lower (51.77 percent) at 550 C than without catalyst (62.16 percent). Therefore, pyrolysis using Mo-HZSM-5 as a catalyst has proved to increase the amount of hydrocarbon in bio-oil while lighter hydrocarbons were enhanced at lower temperatures (400 C) by the cracking of larger hydrocarbon molecules.
Implementasi Metode Role Playing Pada Mata Pelajaran Fiqih Dan Implikasinya Terhadap Pemahaman Siswa Pada Materi Memandikan Jenazah (Studi di Kelas IX 1 MTsN 1 GARUT)
Authors: Sulaiman Husnan , Dewi Lyusni Anisa 
Published: October 2024

Penelitian ini dilatarbelakangi oleh perhatian peneliti terhadap kelangsungan proses belajar mengajar pada peningkatan pemahaman siswa dalam mata pelajaran fiqih, khususnya pada materi pembelajaran yang bersifat praktik, dimana menurut hasil observasi masih banyak siswa kelas IX di MTsN 1 Garut yang terlihat masih kurang daya pemahamannya tentang praktik memandikan jenazah, sehingga diperlukan penerapan metode pembelajaran yang bersifat praktikum. Tujuan daripada penelitian ini adalah untuk; 1). Terdiskripsikannya Pemahaman Siswa Kelas IX 1 terhadap Praktik Memandikan Jenazah di Madrasah Tsanawiyah Negeri 1 Garut. 2). Terdeskripsikannya Implementasi Metode Pembelajaran Role Playing tentang Praktik Memandikan Jenazah Kelas IX 1 di Madrasah Tsanawiyah Negeri 1 Garut. 3). Terdeskripsikannya Implementasi Metode Pembelajaran Role Playing tentang Praktik Memandikan Jenazah terhadap Pemahaman Siswa Kelas IX 1 di Madrasah Tsanawiyah Negeri 1 Garut. Adapun metode yang digunakan dalam penelitian ini adalah metode kualitatif deskriptif, yakni metode yang bertujuan untuk memaparkan atau menggambarkan kejadian di lapangan. Disamping itu, didukung pula oleh metode library research (kajian putaka). Sumber data yang digunakan dalam penelitian ini adalah sumber primer ; pengamatan proses pembelajaran dan praktikum memandikan jenazah yang berlangsung di MTsN 1 Garut dan sumber sekunder ; buku-buku atau bahan bacaan lainnya yang berhubungan langsung dengan penelitian ini. Teknik pengumpulan data dalam penelitian ini terdiri dari observasi, wawancara dan dokumentasi. Adapun teknik analisis data dalam penelitian ini yaitu reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa Implementasi Metode Role Playing Pada Mata Pelajaran Fiqih dan Implikasinya terhadap Pemahaman Siswa mampu memenuhi 4 dari 7 indikator pemahaman yang ada. Demikian temuan yang diperoleh dari penelitian ini.
Kata Kunci : Metode Pembelajaran Role Playing, Mata Pelajaran Fiqih, Pemahaman Siswa
Media Pembelajaran Perspektif Al-Qur’an Surah Al-Baqarah Ayat 31
Authors: Izzan Ahmad , Nuraeni Neni 
Published: October 2024

Media pembelajaran merupakan salah satu aspek yang harus dikuasai oleh pendidik. Merupakan salah satu faktor yang sangat berpengaruh terhadap keberhasilan proses belajar mengajar. Dengan mengunakan media pembelajaran yang bervariasi akan dapat menumbuhkembangkan minat dan bakat siswa dalam belajar, karena dengan menggunakan media pembelajaran yang bermacam-macam dapat memudahkan siswa dalam menangkap sebuah materi dan peserta didik tidak akan merasa mudah cepat bosan dan jenuh sehingga akan terjadinya interaksi langsung antara pendidik dan peserta didik. Dalam Al-Qur’an banyak ayat yang di dalamnya terdapat tentang media pembelajaran salah-satunya dalam Q.S Al-Baqarah Ayat 31. Dalam Al-Qur’an Surat Al-Baqarah Ayat 31 memuat beberapa nilai yang didalamnya berkaitan dengan media pembelajaran. Penelitian ini bertujuan untuk mendeskripsikan media pembelajaran yang terkandung dalam Al-Qur’an Surat Al-Baqarah Ayat 31. Penelitian ini merupakan jenis penelitian kepustakaan (Library Research) melalui pendekatan bersifat metode analis selain itu juga digunakan pendekatan studi komparatif terkait akibat atau faktor yang terjadi sesuatu berdasarkan dokumen dan pustaka. Penelitian induktif adalah penelitian yang bertujuan untuk mengembangkan (generating) teori melalui pengungkapan fakta dengan cara melakukan penelitian terhadap penafsiran para mufasir terhadap Q.S Al-Baqarah ayat 31 dan sumber-sumber tertulis tentang media pembelajaran yang dikemukakan oleh para ahli atau oleh para ulama. Metode penelitian yang digunakan yaitu metode kualitatif dengan berfokus pada analisis konten Al-Qur’an Surat Al-Baqarah Ayat dan isi teks buku-buku. Berdasarkan hasil penelitian, dapat disimpulkan bahwa nilai yang terkandung dalam Al-Qur’an Surat Al-Baqarah Ayat 31 ini berkaitan dengan media pembelajaran adalah al-asma yaitu benda-benda.
Kata Kunci : Media Pembelajaran, Al-Qur’an Surat Al-Baqarah Ayat 31