bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating the content and process of capability development: Lessons from theoretical and methodological developments
Authors: Kashan Alireza J. , Mohannak Kavoos 
Published: May 2017

AbstractThe literature on capability development has focussed on either the content or process of capability development. Such a partial explanation of the capability development phenomenon has created some flaws in the literature. This paper argues that integrating the content and process of capability development is the way ahead in theorising in this field. Analysis of the methodological development in parallel to theory development reveals the critical role of microprocesses in such integration. To develop an integrative view of capability development we propose a conceptualisation of capability development processes through internal and external strategic fit and emphasise the role of knowledge and innovation processes. We also argue that a critical realism approach is of high relevance to researching such an integrative view.
A P-MINIMAL STRUCTURE WITHOUT DEFINABLE SKOLEM FUNCTIONS
Authors: KOVACSICS PABLO CUBIDES , NGUYEN KIEN HUU 
Published: May 2017

AbstractWe show there are intermediate P-minimal structures between the semialgebraic and subanalytic languages which do not have definable Skolem functions. As a consequence, by a result of Mourgues, this shows there are P-minimal structures which do not admit classical cell decomposition.
When Do Conflicts Feel Right for Prevention-Focused Individuals? The Debiasing Effect of Low Need for Closure
Authors: Zhang Zhi-Xue , Wei Xin , Chao Melody Manchi , Zheng Yi 
Published: May 2017

ABSTRACTBoth lay beliefs and research findings suggest that people tend to avoid conflicts if interpersonal harmony is highly valued. Counter to this widely accepted convention, we adopt the perspective of motivated social cognition to argue that conflict avoidance is subject to the joint effect of the need for epistemic security (need for closure) and the motivation to prevent losses (prevention focus). Such effect is mediated by negative anticipation towards the consequences of confronting conflicts. Results across three studies indicated that individuals with relatively high need for closure and high prevention focus show the strongest conflict avoidance tendency due to their heightened negative anticipation. However, with low need for closure, the negative anticipation and conflict avoidance tendency of high prevention-focused individuals are weakened or even disappear. This research offers a novel theory about the mechanism of conflict avoidance. The findings about the debiasing role of low need for closure also provide rich implications for conflict resolutions.
Craniodental functional evolution in sauropodomorph dinosaurs
Authors: Button David J. , Barrett Paul M. , Rayfield Emily J. 
Published: May 2017

AbstractSauropodomorpha included the largest known terrestrial vertebrates and was the first dinosaur clade to achieve a global distribution. This success is associated with their early adoption of herbivory, and sauropod gigantism has been hypothesized to be a specialization for bulk feeding and obligate high-fiber herbivory. Here, we apply a combination of biomechanical character analysis and comparative phylogenetic methods with the aim of quantifying the evolutionary mechanics of the sauropodomorph feeding apparatus. We test for the role of convergence to common feeding function and divergence toward functional optima across sauropodomorph evolution, quantify the rate of evolution for functional characters, and test for coincident evolutionary rate shifts in craniodental functional characters and body mass. Results identify a functional shift toward increased cranial robustness, increased bite force, and the onset of static occlusion at the base of the Sauropoda, consistent with a shift toward bulk feeding. Trends toward similarity in functional characters are observed in Diplodocoidea and Titanosauriformes. However, diplodocids and titanosaurs retain significant craniodental functional differences, and evidence for convergent adoption of a common “adaptive zone” between them is weak. Modeling of craniodental character and body-mass evolution demonstrates that these functional shifts were not correlated with evolutionary rate shifts. Instead, a significant correlation between body mass and characters related to bite force and cranial robustness suggests a correlated-progression evolutionary mode, with positive-feedback loops between body mass and dietary specializations fueling sauropod gigantism.
Paired Radiocarbon Dating on Human Samples and Camelid Fibers and Textiles from Northern Chile: The Case of Pica 8 (Tarapacá)
Authors: Santana-Sagredo Francisca , Schulting Rick , Lee-Thorp Julia , Agüero Carolina , Uribe Mauricio , Lemp Cecilia 
Published: May 2017

AbstractPica 8 is a Late Intermediate Period (AD 900–1450) cemetery located in the Atacama Desert. Burials at the site present unexpectedly high variability in δ13C (–8‰ to –16‰) and δ15N (10‰ to 24‰) values in their skeletal tissues, implying highly diverse diets. There are two possible explanations for this variability: the first is diachronic change in diet while the second involves synchronic sociocultural distinctions. To distinguish between them a radiocarbon (14C) dating program (n=23) was initiated. The presumed importance of marine foods adds the complication of a marine reservoir effect. To address this problem, paired 14C dates were obtained on human bone and camelid textiles from nine graves. The results fall into two groups, one showing an average offset of 117±9 14C yr, and the other no statistically significant offsets. We conclude that the contribution of marine foods to bone collagen at Pica 8 was less than previously supposed. Other factors must be invoked to account for the unusually high human δ15N values at the site. Manuring crops with sea-bird guano emerges as a probable explanation. No relationship with chronology is seen implying the presence of considerable diversity in diets and hence lifeways within the Pica 8 community.
Seasonal 14C and Sr/Ca Records of a Modern Coral around Daya Bay Nuclear Power Plants
Authors: Wang Ning , Shen Chengde , Sun Weidong , Yi Weixi , Ding Ping , Ding Xingfang , Fu Dongpo , Liu Kexin 
Published: May 2017

ABSTRACTDue to an increasing number of nuclear reactors in operation, the radiocarbon (14C) released from nuclear power plants (NPPs) has become an important anthropogenic source of 14C. The examination of seasonal Δ14C and monthly Sr/Ca, Mg/Ca variations in a coral in Daya Bay (China) shows that NPPs located there have an impact on the Δ14C level and sea surface temperature (SST). The Mg/Ca variation was in good correlation with the Pacific Decadal Oscillation (PDO) before the operation of Ling’ao NPP in 2002, but this correlation became weak due to an abnormally higher SST after 2002. As illustrated by the Δ14C variation in the coral, there were two relative increases of Δ14C values in 1994 and 2002 when Daya Bay NPP and Ling’ao NPP began operations, respectively. The 14C released from NPPs, instead of oceanic circulation, is probably the primary factor on the Δ14C variation in Daya Bay during the NPPs’ operation. The relative increase in Δ14C value was ~80‰, which equals to ~18 Bq/kgC in specific activity. The seasonal variability in Δ14C value usually peaked in summer, the real reason of which was unknown. This study sheds light on how the NPPs influence the 14C content and SST in surrounding marine environment.
Conversion ratios ofn-3 fatty acids between plasma and erythrocytes: a systematic review and meta-regression
Authors: Hu Xue Feng , Sandhu Simran K. , Harris William S. , Chan Hing Man 
Published: May 2017

AbstractAs biomarkers of dietary intake or disease risk factor,n-3 fatty acid (FA) can be measured in plasma phospholipids (PL), total lipids (TL) or erythrocytes. However, the numeric relationships betweenn-3 FA in these lipid pools are not clear. Our goal was to derive conversion ratios for plasma and erythrocyten-3 FA. Potential studies were identified through systematic literature search in PubMed, Embase and the Cochrane Library of Systematic reviews (1950 to October 2014). In all, fifty-six studies reportingn-3 in healthy individuals were included, of which thirty-four articles reported plasma PL and erythrocytes, and twenty-two reported plasma TL and erythrocytes. Meta-regressions were performed to quantify the ratio between plasma and erythrocyten-3 FA weight percentages, controlling for covariates including age, sex and study design. The conversion ratios from plasma PL to erythrocytes for EPA, DHA, DPA and totaln-3 PUFA are 0·75, 1·16, 2·32 and 1·22; the corresponding conversion ratios from plasma TL to erythrocytes are 1·00, 2·10, 3·85 and 2·08, respectively. The conversion ratios were validated using reported values from the literature and measured data from fifty individuals. The relative error of the predicted results were within 10 % of the mean reported values except for EPA, and the individual measured data except for DPA, in plasma TL. The conversion ratios between plasma PL and erythrocytes were more stable compared with plasma TL. Such conversion ratios will be useful for nutritionists or public health professionals to assess FA profiles of different populations using data collected with different methodologies.
A review of bovine fasciolosis and other trematode infections in Nigeria
Authors: Elelu N. , Eisler M.C. 
Published: May 2017

AbstractTrematode infections cause serious economic losses to livestock worldwide. Global production losses due to fasciolosis alone exceed US$3 billion annually. Many trematode infections are also zoonotic and thus a public health concern. The World Health Organization has estimated that about 56 million people worldwide are infected by at least one zoonotic trematode species, and up to 750 million people are at risk of infection. Fasciolosis caused by the flukeFasciola giganticais endemic in Nigeria and is one of the most common causes of liver condemnation in abattoirs. Total cattle losses fromFasciolainfection in Nigeria have been estimated to cost £32.5 million. Other trematode infections of cattle, including paramphistomosis, dicrocoeliasis and schistosomiasis, have all been reported in various parts of Nigeria, with varying prevalence. Most publications on trematode infections are limited to Nigerian local and national journals, with very few international reports. This paper therefore summarized the current data on distribution, control and zoonotic trematode infections in Nigeria and other African countries. We also identified research gaps and made recommendations for future research and areas for funding for policy/planning.
Autism risk following antidepressant medication during pregnancy
Authors: Viktorin A. , Uher R. , Reichenberg A. , Levine S. Z. , Sandin S. 
Published: May 2017

BackgroundPrevious studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have been conflicting.MethodsIn a population-based cohort of 179 007 children born in 2006 and 2007 and followed through 2014 when aged 7 and 8, we estimated relative risks (RRs) of ASD and 95% confidence intervals (CIs) from Cox regression in children exposed to any antidepressant medication during pregnancy, and nine specific antidepressant drugs. Analyses were adjusted for potential confounders and were conducted in the full population sample, and in a clinically relevant sub-sample of mothers with at least one diagnosis of depression or anxiety during life.ResultsThe adjusted RR of ASD in children of mothers who used antidepressant medication during pregnancy was estimated at 1.23 (95% CI 0.96–1.57), and at 1.07 (95% CI 0.80–1.43) in women with a history of depression or anxiety. Analyses of specific antidepressants initially revealed increased RRs of offspring ASD confined to citalopram and escitalopram (RR: 1.47; 95% CI 0.92–2.35) and clomipramine (RR: 2.86; 95% CI 1.04–7.82).ConclusionMedication with antidepressants during pregnancy does not appear to be causally associated with an increased risk of ASD in the offspring. Instead, the results suggest that the association is explained by factors related to the underlying susceptibility to psychiatric disorders. Based on these findings, the risk of ASD in the offspring should not be a consideration to withhold treatment with commonly used antidepressant drugs from pregnant women.
WHY PATIENTS SHOULD BE INVOLVED IN HEALTH TECHNOLOGY ASSESSMENT
Authors: Wale Janet , Scott Anna Mae , Hofmann Bjørn , Garner Sarah , Low Eric , Sansom Lloyd 
Published: May 2017

Objectives: Some countries make considerable effort to involve patients and patient groups in their health technology assessment (HTA) processes; others are only just considering or are yet to consider patient involvement in HTA.Methods: This commentary offers four arguments why patient involvement should be prioritized by those HTA agencies that do not yet involve patients: (1) from a patients’ rights perspective, (2) based on patient and community values, (3) centering on evidentiary contributions, and (4) from a methodological perspective.Results: The first argument builds on the Alma-Ata Declaration, which holds that patients have a right and duty to have a say in the planning and delivery of their health care, individually and collectively. Where HTA is used to determine access to technologies and services, we argue that patients have a right to be heard. The second argues that decisions about treatments and services need to be aligned with the core values and morals of the patients whom the health system serves. The third argues that patients have unique knowledge and insights about living with a health condition and their needs for services and treatments regarding that condition, which can add to the knowledge base and value of the HTA process. The fourth argues that involvement of patients can facilitate methodological advancement of HTA, in areas such as early scientific advice and managed entry with evidence development.Conclusions: An HTA process that includes patient perspectives can, therefore, provide added value to patients, policy makers and healthcare professionals alike.
Unveiling Neoliberal Dynamics: Government Purchase (goumai) of Social Work Services in Shenzhen's Urban Periphery
Authors: Cho Mun Young 
Published: May 2017

AbstractHow has social work, which has emerged as a distinct profession in the PRC with the full support of the party-state, come to produce neoliberal outcomes similar to those found in other, capitalist countries? In this article, I draw attention to the government purchase (goumai) of social work services, which is commonly considered as confirmation of state capacity and leadership rather than the passing on of state responsibilities to civil sectors with tight budgets. Ethnographic research on the actual social work practices in Shenzhen's Foxconn town reveals how neoliberal-style outsourcing has converged with diverse historical legacies, thus creating precarious labour conditions for frontline social workers. Neoliberal dynamics end up filling most of these social work positions with migrant youth from the countryside, reproducing and perpetuating China's rural–urban divide. Institutional efforts at social care may not only reduce the existing inequalities but may also rely upon and even reinforce them.
Persistent infections support maintenance of a coronavirus in a population of Australian bats (Myotis macropus)
Authors: JEONG J. , SMITH C. S. , PEEL A. J. , PLOWRIGHT R. K. , KERLIN D. H. , MCBROOM J. , MCCALLUM H. 
Published: May 2017

SUMMARYUnderstanding viral transmission dynamics within populations of reservoir hosts can facilitate greater knowledge of the spillover of emerging infectious diseases. While bat-borne viruses are of concern to public health, investigations into their dynamics have been limited by a lack of longitudinal data from individual bats. Here, we examine capture–mark–recapture (CMR) data from a species of Australian bat (Myotis macropus) infected with a putative novel Alphacoronavirus within a Bayesian framework. Then, we developed epidemic models to estimate the effect of persistently infectious individuals (which shed viruses for extensive periods) on the probability of viral maintenance within the study population. We found that the CMR data analysis supported grouping of infectious bats into persistently and transiently infectious bats. Maintenance of coronavirus within the study population was more likely in an epidemic model that included both persistently and transiently infectious bats, compared with the epidemic model with non-grouping of bats. These findings, using rare CMR data from longitudinal samples of individual bats, increase our understanding of transmission dynamics of bat viral infectious diseases.
A framework for learner agency in online spoken interaction tasks
Authors: Knight Janine , Barbera Elena , Appel Christine 
Published: May 2017

AbstractLearner agency, the capability of individual human beings to make choices and act on these choices in a way that makes a difference in their lives (Martin, 2004), is instrumental in second language learning because attainment is only arrived at by learner choice (Pavlenko & Lantolf, 2000). If attainment is understood as learner engagement in synchronous, collaborative, spoken interaction which is thought to lead to gains in second language acquisition (SLA), then design considerations that harness learners’ agency towards that end is important. This study explores the relationship between learner agency and two different task types, namely an information-gap task and an opinion-sharing task in two peer-to-peer synchronous computer-mediated communication (SCMC) spoken interaction events. Students’ choices and how students act on these choices during tasks are analysed using a discourse analysis approach. Audio recordings of four dyads as cases were examined using three analytical dimensions: language functions of verbal interaction, cognitive processing and social processing. The results show that most learners used their agency to reconfigure the tasks from spontaneous to planned interaction, with some choices and actions relating to technology impacting detrimentally on interaction time in the target language. The different tasks were found to filter and channel different types of agency that learners could exercise, namely representational, organisational, and strategic agency as speech acts, and directional agency as a physical act. These types consisted of different natures and purposes and are presented as a framework. The information-gap task supported strategic agency and an opinion-sharing task supported personalisation and identity construction or representational agency.
Automation Surprise
Authors: de Boer Robert J. , Hurts Karel 
Published: May 2017

Abstract. Automation surprise (AS) has often been associated with aviation safety incidents. Although numerous laboratory studies have been conducted, few data are available from routine flight operations. A survey among a representative sample of 200 Dutch airline pilots was used to determine the prevalence of AS and the severity of its consequences, and to test some of the factors leading to AS. Results show that AS is a relatively widespread phenomenon that occurs three times per year per pilot on average but rarely has serious consequences. In less than 10% of the AS cases that were reviewed, an undesired aircraft state was induced. Reportable occurrences are estimated to occur only once every 1–3 years per pilot. Factors leading to a higher prevalence of AS include less flying experience, increasing complexity of the flight control mode, and flight duty periods of over 8 hr. It is concluded that AS is a manifestation of system and interface complexity rather than cognitive errors.
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia
Authors: Makarev Eugene , Schubert Adrian D , Kanherkar Riya R , London Nyall , Teka Mahder , Ozerov Ivan , Lezhnina Ksenia , Bedi Atul , Ravi Rajani , Mehra Rannee , Hoque Mohammad O , Sloma Ido , Gaykalova Daria A , Csoka Antonei B , Sidransky David , Zhavoronkov Alex , Izumchenko Evgeny 
Published: May 2017

AbstractA subset of patients with oral squamous cell carcinoma (OSCC), the most common subtype of head and neck squamous cell carcinoma (HNSCC), harbor dysplastic lesions (often visually identified as leukoplakia) prior to cancer diagnosis. Although evidence suggest that leukoplakia represents an initial step in the progression to cancer, signaling networks driving this progression are poorly understood. Here, we applied in silico Pathway Activation Network Decomposition Analysis (iPANDA), a new bioinformatics software suite for qualitative analysis of intracellular signaling pathway activation using transcriptomic data, to assess a network of molecular signaling in OSCC and pre-neoplastic oral lesions. In tumor samples, our analysis detected major conserved mitogenic and survival signaling pathways strongly associated with HNSCC, suggesting that some of the pathways identified by our algorithm, but not yet validated as HNSCC related, may be attractive targets for future research. While pathways activation landscape in the majority of leukoplakias was different from that seen in OSCC, a subset of pre-neoplastic lesions has demonstrated some degree of similarity to the signaling profile seen in tumors, including dysregulation of the cancer-driving pathways related to survival and apoptosis. These results suggest that dysregulation of these signaling networks may be the driving force behind the early stages of OSCC tumorigenesis. While future studies with larger leukoplakia data sets are warranted to further estimate the values of this approach for capturing signaling features that characterize relevant lesions that actually progress to cancers, our platform proposes a promising new approach for detecting cancer-promoting pathways and tailoring the right therapy to prevent tumorigenesis.
Exploiting biased reptation for continuous flow preparative DNA fractionation in a versatile microfluidic platform
Authors: Gumuscu Burcu , Bomer Johan G. , de Boer Hans L. , van den Berg Albert , Eijkel Jan C. T. 
Published: May 2017

AbstractA new approach is presented for preparative, continuous flow fractionation of sub-10-kbp DNA fragments, which exploits the variation in the field-dependent mobility of the DNA molecules based on their length. Orthogonally pulsed electric fields of significantly different magnitudes are applied to a microchip filled with a sieving matrix of 1.2% agarose gel. Using this method, we demonstrate a high-resolution separation of 0.5, 1, 2, 5, and 10 kbp DNA fragments within 2 min. During the separation, DNA fragments are also purified from other ionic species. Preparative fractionation of sub-10-kbp DNA molecules plays an important role in second-generation sequencing. The presented device performs rapid high-resolution fractionation and it can be reliably manufactured with simple microfabrication procedures.