bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laparoscopic Ovarian Drilling in Clomiphene-resistant Polycystic Ovarian Syndrome Women: A Retrospective Analysis
Authors: Kamath Mohan S , Thomas Sumi , Vithayathil Vivek P , Chandy Achamma , Aleyamma Thaiparambil K 
Published: December 2017

ABSTRACTIntroductionOvulation induction in women with polycystic ovarian syndrome (PCOS) can be carried out with drugs, such as clomiphene citrate (CC), which remains the first-line treatment option, and surgery, such as laparoscopic ovarian drilling (LOD), which is usually recommended as one of the second-line treatment options. Laparoscopic ovarian drilling may avoid or reduce the need for gonadotropins and at the same time reduce ovarian hyperstimulation syndrome (OHSS) and multiple pregnancy.AimWe aimed to evaluate the effectiveness of LOD in clomiphene-resistant women and to identify the clinical factors that might predict its success.Study designRetrospective analysis in a tertiary level infertility unit.Materials and methodsAll CC-resistant PCOS women who underwent LOD over a 10-year period were included. Polycystic ovarian syndrome was defined as per the Rotterdam criteria. The follow-up period was up to 3 years post-LOD. Outcomes, such as onset of regular cycles, spontaneous pregnancies, and live births were recorded.ResultsA total of 59 PCOS women who underwent LOD and were available for follow-up were included in the study. Majority of the patients were less than 30 years of age with a body mass index (BMI) > 24 kg/m2. Out of those, 12 conceived (20.3%) spontaneously and 14 (23.7%) had regular menstrual cycles after the procedure. The live birth rate was 16.9% (10/59). We did not find any association of clinical factors, such as age, BMI, type of infertility, and history of irregular cycles with LOD success.ConclusionLaparoscopic ovarian drilling can be offered as a treatment option in select group of CC-resistant women with reasonable success. Post-LOD, for those who do not have resumption of regular cycles, alternate method of ovulation induction can be initiated.How to cite this articleThomas S, Vithayathil VP, Chandy A, Aleyamma TK, Kamath MS. Laparoscopic Ovarian Drilling in Clomiphene-resistant Polycystic Ovarian Syndrome Women: A Retrospective Analysis. Int J Infertil Fetal Med 2017;8(3):93-96.
Study on Infertility—Etiology, Medication Therapy Management, and Outcomes at a Tertiary Care Hospital
Authors: Khanuja Purvi K , Sunny Juby A , Pawar Sunita B 
Published: December 2017

ABSTRACT

Aim
The aim of the article is to study infertility—etiology, medication therapy management, and outcomes in a tertiary care hospital.

Objectives
The purpose of this study was to compare the outcomes of standard aetiology wise treatment protocols of infertility and the various causes which may be a contributing factor to infertility.

Materials and methods
A prospective observational study was conducted for 6 months at a tertiary care hospital. Couples diagnosed with infertility, aged 18 to 49 years were enrolled in the study. Details like couple's sociodemographic data, etiology, risk factors associated with infertility, management with current medications, procedures, and outcomes were documented using predesigned infertility proforma.

Results
Females had an age group of 19 to 38 years with an average age and standard deviation (SD) of 25.64 ± 4.07 years, whereas male patients had an age of 24 to 43 years with a mean age and SD of 30.59 ± 4.17 years. Primary infertility was 59.13% and secondary infertility 40.86%. In women with infertility, ovulatory disorders were the chief cause, followed by unexplained factor, uterine tubal, and more than one cause, whereas in males semen abnormalities were the major cause of both primary and secondary infertility, followed by unexplained, anatomical, more than one cause. Medical therapy involving drugs like clomiphene, gonadotropins, and a combination was administered to females. Males received lycopene, L-carnitine, ubidecarenone, zinc, and astaxanthin. Intrauterine insemination (IUI) was performed in 28 patients. From the available data of 100 couples undergoing management for infertility in the 6 months study period, 19 patients conceived, i.e., 19% showed conception.

Conclusion
The present study shows etiological and pathological causes of infertility. The study highlights positive results with standard treatments.

Clinical significance
To identify hidden social, medical, pathological, and other confounding causes leading to infertility.

How to cite this article
Khanuja PK, Sunny JA, Pawar SB, Nimbargi V. Study on Infertility—Etiology, Medication Therapy Management, and Outcomes at a Tertiary Care Hospital. Int J Infertil Fetal Med 2017;8(3):106-112.
Curriculum-Level Strategies That U.S. Occupational Therapy Programs Use to Address Occupation: A Qualitative Study
Authors: Hooper Barb , Krishnagiri Sheama , Price Pollie , Taff Steven D. , Bilics Andrea 
Published: December 2017

Abstract
OBJECTIVE. This study’s objective was to describe curriculum-level strategies used to convey occupation to occupational therapy students.
METHOD. The study used a descriptive qualitative research design. Fifteen occupational therapy and 10 occupational therapy assistant programs participated in interviews, submitted curriculum artifacts such as syllabi and assignments, and recorded teaching sessions. Data were coded both inductively and deductively and then categorized into themes.
RESULTS. Occupational therapy programs designed strategies on two levels of the curriculum, infrastructure and implementation, to convey knowledge of occupation to students. The degree to which strategies explicitly highlighted occupation and steered instruction fluctuated depending on how differentiated occupation was from other concepts and skills.
CONCLUSION. Two arguments are presented about the degree to which occupation needs to be infused in all curricular elements. To guide curriculum design, it is critical for educators to discuss beliefs about how ubiquitous occupation is in a curriculum and whether curricular elements portray occupation to the extent preferred.
Investigation of the Relationship Between Sensory Processing and Motor Development in Preterm Infants
Authors: Celik Halil Ibrahim , Elbasan Bulent , Gucuyener Kivilcim , Kayihan Hulya , Huri Meral 
Published: December 2017

AbstractOBJECTIVE. The aim of this study was to analyze the correlation between sensory processing and motor development in preterm infants.METHOD. We included 30 preterm and 30 term infants with corrected and chronological ages between 10 and 12 mo. We used the Test of Sensory Functions in Infants to evaluate sensory processing and the Alberta Infant Motor Scale to evaluate motor development.RESULTS. The Spearman correlation test indicated a strong positive relationship between sensory processing and motor development in preterm infants (r = .63, p &lt; .001).CONCLUSION. Given the relationship between sensory processing and motor development in the preterm group, the evaluation of sensory processing and motor development in preterm infants was considered necessary for the effective implementation of physiotherapy assessment and interventions.
Modeling impacts of climate change and grazing effects on plant biomass and soil organic carbon in the Qinghai–Tibetan grasslands
Authors: Zhang Wenjuan , Zhang Feng , Qi Jiaguo , Hou Fujiang 
Published: December 2017

Abstract. The Qinghai Province supports over 40 % of the human population of the Qinghai–Tibetan Plateau (QTP) but occupies about 29 % of its land area, and thus it plays an important role in the plateau. The dominant land cover is grassland, which has been severely degraded over the last decade due to a combination of increased human activities and climate change. Numerous studies indicate that the plateau is sensitive to recent global climate change, but the drivers and consequences of grassland ecosystem change are controversial, especially the effects of climate change and grazing patterns on the grassland biomass and soil organic carbon (SOC) storage in this region. In this study, we used the DeNitrification-DeComposition (DNDC) model and two climate change scenarios (representative concentration pathways: RCP4.5 and RCP8.5) to understand how the grassland biomass and SOC pools might respond to different grazing intensities under future climate change scenarios. More than 1400 grassland biomass sampling points and 46 SOC points were used to validate the simulated results. The simulated above-ground biomass and SOC concentrations were in good agreement with the measured data (R2 0.71 and 0.73 for above-ground biomass and SOC, respectively). The results showed that climate change may be the major factor that leads to fluctuations in the grassland biomass and SOC, and it explained 26.4 and 47.7 % of biomass and SOC variation, respectively. Meanwhile, the grazing intensity explained 6.4 and 2.3 % variation in biomass and SOC, respectively. The project average biomass and SOC between 2015 and 2044 was significantly smaller than past 30 years (1985–2014), and it was 191.17 g C m−2, 63.44 g C kg−1 and 183.62 g C m−2, 63.37 g C kg−1 for biomass and SOC under RCP4.5 and RCP8.5, respectively. The RCP8.5 showed the more negative effect on the biomass and SOC compared with RCP4.5. Grazing intensity had a negative relationship with biomass and positive relationship with SOC. Compared with the baseline, the biomass and SOC changed by 12.56 and −0.19 % for G0, 7.23 and 0.23 for G−50, and −5.17 and 1.19 % for G+50. In the future, more human activity and management practices should be coupled into the model simulation.
Three distinct Holocene intervals of stalagmite deposition and nondeposition revealed in NW Madagascar, and their paleoclimate implications
Authors: Voarintsoa Ny Riavo Gilbertinie , Railsback Loren Bruce , Brook George Albert , Wang Lixin , Kathayat Gayatri , Cheng Hai , Li Xianglei , Edwards Richard Lawrence , Rakotondrazafy Amos Fety Michel , Madison Razanatseheno Marie Olga 
Published: December 2017

Abstract. Petrographic features, mineralogy, and stable isotopes from two stalagmites, ANJB-2 and MAJ-5, respectively from Anjohibe and Anjokipoty caves, allow distinction of three intervals of the Holocene in NW Madagascar. The Malagasy early Holocene (between ca. 9.8 and 7.8 ka) and late Holocene (after ca. 1.6 ka) intervals (MEHI and MLHI, respectively) record evidence of stalagmite deposition. The Malagasy middle Holocene interval (MMHI, between ca. 7.8 and 1.6 ka) is marked by a depositional hiatus of ca. 6500 years. Deposition of these stalagmites indicates that the two caves were sufficiently supplied with water to allow stalagmite formation. This suggests that the MEHI and MLHI intervals may have been comparatively wet in NW Madagascar. In contrast, the long-term depositional hiatus during the MMHI implies it was relatively drier than the MEHI and the MLHI. The alternating wet–dry–wet conditions during the Holocene may have been linked to the long-term migrations of the Intertropical Convergence Zone (ITCZ). When the ITCZ's mean position is farther south, NW Madagascar experiences wetter conditions, such as during the MEHI and MLHI, and when it moves north, NW Madagascar climate becomes drier, such as during the MMHI. A similar wet–dry–wet succession during the Holocene has been reported in neighboring locations, such as southeastern Africa. Beyond these three subdivisions, the records also suggest wet conditions around the cold 8.2 ka event, suggesting a causal relationship. However, additional Southern Hemisphere high-resolution data will be needed to confirm this.
Impact of asymmetric uncertainties in ice sheet dynamics on regional sea level projections
Authors: de Winter Renske C. , Reerink Thomas J. , Slangen Aimée B. A. , de Vries Hylke , Edwards Tamsin , van de Wal Roderik S. W. 
Published: December 2017

Abstract. Currently a paradigm shift is made from global averaged to spatially variable sea level change (SLC) projections. Traditionally, the contribution from ice sheet mass loss to SLC is considered to be symmetrically distributed. However, several assessments suggest that the probability distribution of dynamical ice sheet mass loss is asymmetrically distributed towards higher SLC values. Here we show how asymmetric probability distributions of dynamical ice sheet mass loss impact the high-end uncertainties of regional SLC projections across the globe. For this purpose we use distributions of dynamical ice sheet mass loss presented by Church et al. (2013), De Vries and Van de Wal (2015) and Ritz et al. (2015). The global average median can be 0.18 m higher compared to symmetric distributions based on IPCC-AR5, but the change in the global average 95th percentile SLC is considerably larger with a shift of 0.32 m. Locally the 90th, 95th and 97.5th SLC percentiles exceed +1.4, +1.6 and +1.8 m. The high-end percentiles of SLC projections are highly sensitive to the precise shape of the probability distributions of dynamical ice sheet mass loss. The shift towards higher values is of importance for coastal safety strategies as they are based on the high-end percentiles of projections.
Dynamical properties and extremes of Northern Hemisphere climate fields over the past 60 years
Authors: Faranda Davide , Messori Gabriele , Alvarez-Castro M. Carmen , Yiou Pascal 
Published: December 2017

Abstract. Atmospheric dynamics are described by a set of partial differential equations yielding an infinite-dimensional phase space. However, the actual trajectories followed by the system appear to be constrained to a finite-dimensional phase space, i.e. a strange attractor. The dynamical properties of this attractor are difficult to determine due to the complex nature of atmospheric motions. A first step to simplify the problem is to focus on observables which affect – or are linked to phenomena which affect – human welfare and activities, such as sea-level pressure, 2 m temperature, and precipitation frequency. We make use of recent advances in dynamical systems theory to estimate two instantaneous dynamical properties of the above fields for the Northern Hemisphere: local dimension and persistence. We then use these metrics to characterize the seasonality of the different fields and their interplay. We further analyse the large-scale anomaly patterns corresponding to phase-space extremes – namely time steps at which the fields display extremes in their instantaneous dynamical properties. The analysis is based on the NCEP/NCAR reanalysis data, over the period 1948–2013. The results show that (i) despite the high dimensionality of atmospheric dynamics, the Northern Hemisphere sea-level pressure and temperature fields can on average be described by roughly 20 degrees of freedom; (ii) the precipitation field has a higher dimensionality; and (iii) the seasonal forcing modulates the variability of the dynamical indicators and affects the occurrence of phase-space extremes. We further identify a number of robust correlations between the dynamical properties of the different variables.
Submesoscale CO2 variability across an upwelling front off Peru
Authors: Köhn Eike E. , Thomsen Sören , Arévalo-Martínez Damian L. , Kanzow Torsten 
Published: December 2017

Abstract. As a major source for atmospheric CO2, the Peruvian upwelling region exhibits strong variability in surface fCO2 on short spatial and temporal scales. Understanding the physical processes driving the strong variability is of fundamental importance for constraining the effect of marine emissions from upwelling regions on the global CO2 budget. In this study, a frontal decay on length scales of 𝒪(10 km) was observed off the Peruvian coast following a pronounced decrease in down-frontal (equatorward) wind speed with a time lag of 9 h. Simultaneously, the sea-to-air flux of CO2 on the inshore (cold) side of the front dropped from up to 80 to 10 mmol m−2 day−1, while the offshore (warm) side of the front was constantly outgassing at a rate of 10–20 mmol m−2 day−1. Based on repeated ship transects the decay of the front was observed to occur in two phases. The first phase was characterized by a development of coherent surface temperature anomalies which gained in amplitude over 6–9 h. The second phase was characterized by a disappearance of the surface temperature front within 6 h. Submesoscale mixed-layer instabilities were present but seem too slow to completely remove the temperature gradient in this short time period. Dynamics such as a pressure-driven gravity current appear to be a likely mechanism behind the evolution of the front.
“Shadowy Objects in Test Tubes”: The Ethics of Grievance in Kazuo Ishiguro'sNever Let Me Go
Authors: Schwetman John David 
Published: December 2017

AbstractEvery community demands sacrifices from individuals within it, and sometimes such sacrifices can be extreme. To experience harm related to this sort of sacrifice is to be in a state of grievance. Kazuo Ishiguro's 2005 novel Never Let Me Go offers readers a compelling fictional account of severe grievance experienced by its narrator-protagonist and other clones destined to die young when donating their organs to non-clone, or “normal,” members of their community. By presenting radically aggrieved clones as visibly indistinguishable from the “normals,” Ishiguro dramatically challenges traditional understandings of the state of grievance and compels readers to re-examine their own reactions when confronting the spectacle of grievance.
“A Good and Necessary Thing”: Genre and Justice in Octavia Butler'sBloodchild and Other Stories
Authors: Humann Heather Duerre 
Published: December 2017

AbstractWidely recognized as a science fiction writer, and one of a number of prominent black science fiction writers publishing in English, Octavia Butler's “work needs to be understood within the context of the traditions of the genre” of science fiction, a point Patricia Melzer makes in her book, Alien Constructions: Science Fiction and Feminist Thought. Discussing Octavia Butler's fiction and its genre, however, means going beyond simply using the term science fiction to describe the many literary works she wrote over her prolific and decades-long career.
Políticas del urbanismo lúdico. Contracultura y ciudad del situacionismo al neohistoricismo (1943-1989)
Authors: Gómez Gutiérrez Juan José 
Published: December 2017

Este artículo ofrece una introducción histórica a la teoría y la práctica situacionista en conexión con la arquitectura funcionalista, las economías urbanas, ejemplos de acción política contracultural y su reincorporación a las lógicas de organización tecnocrática de las ciudades. Ello permite definir, desde una perspectiva histórica, algunas claves interpretativas de los rasgos ideológicos y económicos fundamentales de los sistemas urbanos contemporáneos, lo cual, a su vez puede establecer un contexto desde el que reflexionar sobre las posibilidades actuales de un urbanismo socialmente comprometido.
Aquest article presenta una introducció històrica a la teoria i la pràctica situacionista en connexió amb l'arquitectura funcionalista, les economies urbanes, exemples d'acció política contracultural i la seva reincorporació a les lògiques d'organització tecnocràtica de les ciutats. Això permet definir, des d'una perspectiva històrica, algunes claus interpretatives dels trets ideològics i econòmics fonamentals dels sistemes urbans contemporanis, la qual cosa, al seu torn pot establir un context des del qual reflexionar sobre les possibilitats actuals d'un urbanisme socialment compromès.
This article offers a historical introduction to situationist theory and practice in connection with functionalist architecture, urban economies, examples of countercultural political action and their recuperation within the logics of technocratic organization of cities.This allows us to define, from a genealogical perspective, some key interpretations of the main ideological and economic features of contemporary urban systems, which in turn can provide with a context to reflect upon current possibilities for a socially committed urbanism.
Hacia una nueva concepción del espacio público en el Teruel de la Edad Moderna: desde el S.XVI hasta el inicio del S.XIX
Authors: Sancho Mir Miguel , Agustín Hernández Luis , Llopis Verdú Jorge 
Published: December 2017

Los diversos estudios sobre la evolución urbana de Teruel han profundizado especialmente en dos momentos clave para entender la morfología de su centro histórico: el periodo fundacional en la Edad Media, y la devastación y posterior reconstrucción sufrida por la ciudad como consecuencia de la guerra civil española ya en el siglo XX. El presente artículo pretende revalorizar una etapa crucial para la evolución del espacio público turolense, como fue la Edad Moderna, mediante el estudio de las diversas fuentes históricas existentes: escritas, gráficas y arqueológicas, que además ha permitido la restitución de la cartografía historiográfica, constatando la importancia de la trasformación formal y conceptual sufrida por el espacio público, que rompe el estrecho cerco de las murallas medievales, abriéndose a nuevos horizontes. Procesos formativos que hay que conocer para entender el pasado, el presente y el futuro de nuestras ciudades.
Els diversos estudis sobre l'evolució urbana de Terol han aprofundit especialment en dos moments clau per entendre la morfologia del seu centre històric: el període fundacional en l'Edat Mitjana, i la devastació i posterior reconstrucció soferta per la ciutat com a conseqüència de la guerra civil espanyola ja en el segle XX. El present article pretén revaloritzar una etapa crucial per a l'evolució de l'espai públic de Terol, com va ser l'Edat Moderna, mitjançant l'estudi de les diverses fonts històriques existents: escrites, gràfiques i arqueològiques, que a més ha permès la restitució de la cartografia historiogràfica, constatant la importància de la transformació formal i conceptual soferta per l'espai públic, que trenca l'estret setge de les muralles medievals, obrint-se a nous horitzons. Processos formatius que cal conèixer per entendre el passat, el present i el futur de les nostres ciutats.
Academic literature on Teruel urban development has mainly focused on two periods when analysing the city's historic centre morphology: the foundational Middle Ages and the reconstruction following the Spanish Civil War - well into the twentieth century. This article underlines the Early Modern era as a crucial period in the development of Teruel public space. I use written, graphic and archaeological sources to restore the historiographical mapping of the city. The article demonstrates the significant formal and conceptual transformation that Teruel public space underwent in that period, as the city went beyond the constricted limits of the medieval walls opening new horizons. These are key formative processes necessary to gain a proper understanding of the past, the present and the future of our cities.
Portada, índice y editorial del número monográfico especial "Inmigración, vivienda y ciudad: Condiciones habitacionales, urbanas y de acceso a la vivienda, consecuencias urbanas y sociales y criterios de actuación para Barcelona y Madrid"
Authors: Garcia-Almirall M. Pilar 
Published: December 2017

Portada, índex i editorial del número monogràfic especial "Immigració, habitatge i ciutat: Condicions habitacionals, urbanes i d'accés a l'habitatge, conseqüències urbanes i socials i criteris d'actuació per Barcelona i Madrid", projecte finançat pel Ministeri de Ciència i Innovació (CSO2008-04337/SOCI) del Govern d'Espanya.
Cover, index and editorial of special issue "Immigration, housing and city housing conditions, and access to urban housing, urban and social consequences and performance criteria for Barcelona and Madrid" project funded by the Ministry of Science and Innovation (CSO2008-04337/SOCI) of the Government of Spain.
Portada, índice y editorial del número monográfico especial "Inmigración, vivienda y ciudad: Condiciones habitacionales, urbanas y de acceso a la vivienda, consecuencias urbanas y sociales y criterios de actuación para Barcelona y Madrid", proyecto financiado por el Ministerio de Ciencia e Innovación (CSO2008-04337/SOCI) del Gobierno de España.