bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of electrophysiology in guiding near-total resection for preservation of facial nerve function in the surgical treatment of large vestibular schwannomas
Authors: Bernardeschi Daniele , Pyatigorskaya Nadya , Vanier Antoine , Bielle Franck , Smail Mustapha , Lamas Georges , Sterkers Olivier , Kalamarides Michel 
Published: April 2017

OBJECTIVEIn large vestibular schwannoma (VS) surgery, the facial nerve (FN) is at high risk of injury. Near-total resection has been advocated in the case of difficult facial nerve dissection, but the amount of residual tumor that should be left and when dissection should be stopped remain controversial factors. The objective of this study was to report FN outcome and radiological results in patients undergoing near-total VS resection guided by electromyographic supramaximal stimulation of the FN at the brainstem.METHODSThis study was a retrospective analysis of a prospectively maintained database. Inclusion criteria were surgical treatment of a large VS during 2014, normal preoperative FN function, and an incomplete resection due to the strong adherence of the tumor to the FN and the loss of around 50% of the response of supramaximal stimulation of the proximal FN at 2 mA. Facial nerve function and the amount and evolution of the residual tumor were evaluated by clinical examination and by MRI at a mean of 5 days postoperatively and at 1 year postoperatively.RESULTSTwenty-five patients met the inclusion criteria and were included in the study. Good FN function (Grade I or II) was observed in 16 (64%) and 21 (84%) of the 25 patients at Day 8 and at 1 year postoperatively, respectively. At the 1-year follow-up evaluation (n = 23), 15 patients (65%) did not show growth of the residual tumor, 6 patients (26%) had regression of the residual tumor, and only 2 patients (9%) presented with tumor progression.CONCLUSIONSNear-total resection guided by electrophysiology represents a safe option in cases of difficult dissection of the facial nerve from the tumor. This seems to offer a good compromise between the goals of preserving facial nerve function and achieving maximum safe resection.
Neuropsychological function after endovascular and neurosurgical treatment of subarachnoid hemorrhage: a systematic review and meta-analysis
Authors: Egeto Peter , Loch Macdonald R. , Ornstein Tisha J. , Schweizer Tom A. 
Published: April 2017

OBJECTIVESubarachnoid hemorrhage (SAH) is treated with either surgical clipping or endovascular coiling, though the latter is the preferred treatment method given its more favorable functional outcomes. However, neuropsychological functioning after treatment is rarely taken into account. In this meta-analysis, the authors synthesized relevant data from the literature and compared neuropsychological functioning in patients after coiling and clipping of SAH. They hypothesized that the coiled patients would outperform the clipped patients; that group differences would be greater with higher posterior circulation rupture rates, in older patients, and in more recent publications; that group differences would be smaller with greater rates of middle cerebral artery (MCA) rupture; and that anterior communicating artery (ACoA) rupture rates would not influence effect sizes.METHODSThe MEDLINE, Embase, and PsycINFO databases were searched for clinical studies that compared neuropsychological functioning after either endovascular coiling or surgical clipping for SAH. Hedge's g and 95% confidence intervals were calculated using random effects models. Patients who had undergone coiling or clipping were compared on test performance in 8 neuropsychological domains: executive functions, language, attention/processing speed, verbal memory, visual memory, spatial memory, visuospatial functions, and intelligence. Patients were also compared with healthy controls, and meta-regressions were used to explore the relation between effect sizes and publication year, delay between treatment and neuropsychological testing, mean patient age, and rates of posterior circulation, ACoA, and MCA ruptures.RESULTSThirteen studies with 396 clipped cases, 314 coiled cases, and 169 healthy controls were included in the study. The coil-treated patients outperformed the clip-treated patients on executive function (g = 0.17, 95% CI 0.08–0.25) and language tests (g = 0.23, 95% CI 0.07–0.39), and all patients were impaired relative to healthy controls (g ranged from −0.93 to −0.29). Coiled patients outperformed clipped patients to a greater degree in more recent publications, over longer posttreatment testing delays, and among older patients. Higher rates of posterior circulation and MCA aneurysms were associated with smaller group differences, while ACoA rupture rates did not influence effect sizes.CONCLUSIONSCoiling of SAH may promote superior neuropsychological functioning under certain circumstances and could have applications for the specialized care of SAH patients.
The Role of Stress as a Risk Factor for Progressive Supranuclear Palsy
Authors: Kelley Kristen D. , Peavy Guerry , Edland Steven , Rogers Whitney , Riley David E. , Bordelon Yvette , Standaert David , Reich Stephen G. , Litvan Irene 
Published: April 2017

Background: PSP, like Alzheimer’s disease (AD), is a tauopathy. The etiopathogenesis of PSP is not well known and the role of stress has not yet been examined. Recent studies have shown that stress increases the risk for developing AD. This study investigates the role of stress as a risk factor for PSP. Objective: B To examine the association between the development of progressive supranuclear palsy (PSP) and self-reported life stressors. Methods: 76 patients diagnosed with PSP according to the NINDS-SPSP criteria and 68 age-matched unrelated controls were administered a life stressor questionnaire. Stress was quantified as total number of events, number of life changing events, and number of events characterized by self-rated severity. Conditional odds ratio (OR) was calculated for each measure, with participants in the highest quartile of each measure being defined as high-exposure in relation to all other participants. Results: There were no significant differences between the reported number of total events or life-changing events in cases and controls. However, we found 24.4% of cases (N = 11) and 9.1% of controls (N = 5) had a higher exposure to high severity events, yielding an OR of 3.2 ( p = 0.04). Conclusions: We found that cases have over a three times greater odds of high exposure to high-severity events than controls prior to the clinical development of PSP, while there were no differences in overall number of reported events. Our findings suggest that high exposure to highly stressful events may be associated with the development of PSP.
Social networks in health care for hypertensive elderly people
Authors: Machado Ana Larissa Gomes , Silva Ana Zaira da , Lima Eveline Fontes Costa , Borges Fernanda Moura , Mota Miriane Da Silva , Formiga Laura Maria Feitosa 
Published: April 2017

Background: Social Networks are characterized by their dynamism and continuous exchange of information, being fundamental to face acute or chronic health conditions and their related problems. It is therefore believed that elderly hypertensive people are inserted in social networks formed through interactions that help them face chronic disease and that such structures include diverse aspects that affect the care processes that are directly related to the perceptions of these patients on hypertension and its treatment.
Aim: To disclose social networks used by elderly hypertensive patients created through the health care offered by health professionals and/or relatives.
Method: descriptive cross sectional study with a qualitative approach developed in two basic care urban units of a Northeastern Brazil municipality during February and March, 2016. The sample was composed of 26 elderly patients of both sexes registered in the selected units. Data collection took place through a semi-structured interview carried out at the patients’ domiciles. Data was processed through the Iramuteq software and analyzed through the Descending Hierarchical Classification (DHC).
Results: results were introduced in two axes: Axe 1: hypertension implications in the life of the elderly according to the following classification: Class 5: pharmacological treatment and side effects; Class 4: hypertension signs and symptoms; Axe 2: hypertension-based links formed with the different classes; Class 2: links that strengthen care; Class 1: pharmacological treatment and side effects; Class 3: professionals who promote hypertensive elderly patients’ care.
Conclusion: interactions developed by hypertensive elderly patients reveal the key role that pharmacological treatment plays in the construction of social networks, negatively affecting the elderly perceptions on the right therapy and highlighting health professionals that promote health care.
Impact Of Wounds In The Assistance To Basic Human Needs In Intensive Care
Authors: Ferreira Jocelly De Araújo , Alves de Lima Nayda Babel , Agra Glenda , Lopes de Souza Priscilla Tereza , Azevedo da Silva Cecilia Jéssica , Medeiros Martins Gabriela 
Published: April 2017

Objective: to understand the impact of soft tissue injuries in the provision of assistance to Basic Human Needs of customers by the nursing staff in the Adult Intensive Care Unit of a hospital in Pernambuco, Brazil.
Methodology: this is a descriptive study with quantitative character, performed with 104 nurses in December 2015. A questionnaire drawn from Wanda Horta's theory was used for data collection.
Results: the most judicious care provided by the multidisciplinary team (81.7%) and the establishment of bond between professionals and clients (57.7%) were found to be the main positive effects. However, negative effects were outstanding, indicated by increased hospital stay (86.5%) and feeling of anxiety (72.1%). Despite the interference of lesions, body care (86%), communication (63.3%), and religiosity/spirituality (43.3%) needs were referred to as met.
Conclusion: the presence of wounds represents a difficulty to meet needs, although they bring some positive impact on the client. However, while recognizing the importance of valuing the customer subjectivity, this aspect is not yet addressed with proper attention.
Keywords: Intensive Care Unit; Injuries; Nursing Care; Basic needs.
Deaths by tuberculosis in a priority city for disease control in the Brazilian Northeast: sociodemographic-operational characteristics and vulnerable territories.
Authors: Santos Neto Marcelino , Da Silva Francisca Bárbara Gomes , Sodré Mariana Borges , Yamamura Mellina , Santos Floriacy Stabnow , Costa Ana Cristina Pereira de Jesus , Serra Maria Aparecida Alves de Oliveira , Gordon Ariadne Siqueira de Araújo , Pascoal Lívia Maia , Bezerra Janaína Miranda , Santos Leonardo Hunaldo dos , Andrade Hamilton Leandro Pinto de , Fontoura Iolanda Graepp , Pieri Flávia Menegheti , Arcêncio Ricardo Alexandre 
Published: April 2017

Introduction: Incorporating spatial approaches into epidemiological research is a challenge in public health research. The goal in this study was to analyze the spatial distribution of cases of deaths by tuberculosis in Imperatriz – MA (Brazil) and to characterize these events according to sociodemographic and operational characteristics.
Methods: In this ecological study, all deaths from tuberculosis as the primary cause registered in the Mortality Information System from 2005 to 2014 were considered. The research variables were subject to descriptive analysis, point density analysis (Kernel Intensity Estimation) and area analysis.
Results: Fifty cases of deaths by TB were identified, particularly the pulmonary clinical form. Male patients were predominant, with a median age of 59 years, mulatto race/color, single, who had finished secondary education. Most deaths happened at the hospital, with medical care before death and without autopsy. Most events happened at the hospital, with medical care delivery by an assistant physician and without autopsy. The point density revealed heterogeneity in the spatial distribution of the deaths, with rates of up to 2.33 deaths/km2. The area analysis by census sector presented age standardized mortality rates of 0.00 to 4.00 deaths/100,000 inhabitants-year.
Conclusion: The results contributed to the knowledge on the spatial distribution of cases of deaths by Tuberculosis and their characteristics in the research scenario. The importance of space is highlighted as a methodological alternative to support the planning, monitoring and assessment of health actions, targeting interventions to the control of the disease in vulnerable territories.
Keywords: Tuberculosis; Health Information Systems; Mortality; Spatial analysis.
Characterization Of Obstetric Assistance At Labor And Childbirth In Low-Risk Women On A Maternity Of Reference To Maternal And Child Health
Authors: Medeiros Maxsuenia Queiroz , Feitosa Francisco Edson Lucena , Pinheiro Ana Karina Bezerra , Neto Raimundo Homero Carvalho , Firmiano Mariana Luisa Veras , Mesquita Debora Rodrigues , Augusto Lucas Costa Carvalho , Carvalho Francisco Herlanio Costa 
Published: April 2017

Objectives: To describe the prevalence of the implementation of obstetric interventions for labor and birth in normal-risk women in reference to maternity Stork Network.
Methodology: cross-sectional study was performed from April 2014 to January 2015, with 421 participants in the Maternity School Assis Chateaubriand - UFC, admitted during spontaneous or induced labor with a live fetus and single pregnancy term and their fetuses weighing between 2,500 and 4.499g. The data collection instrument was divided into blocks with sociodemographic and clinical characteristics, obstetric, data care during labor, delivery and birth, maternal morbidity, maternal outcome and obstetric practices in categories A and B from WHO and perinatal outcomes. The values ​​are presented as mean ± standard deviation.
Results: The age ranged from 13 to 44; the average gestational age at admission was 38.9 ± 1.1 weeks; 52.2% with only one child; 8.6% had a previous cesarean section. There was 96.2% of pre-natal coverage with an average of 6.4 consultations. 76.2% had vaginal delivery. Obstetric practices in category A were more prevalent oxytocin in the third stage (97.1%), partograph (95%), non-invasive methods for pain relief (87.2%), companion (84.6%). While in section B were more of a vaginal examination at 2 hours (50.4%) and intravenous infusion (44.9%) and oxytocin in the expansion phase (28.8%). The present study had as limitations the loss of some data, which depended on the filling of third parties, which are characteristic of searches in medical records, or any documentary archive because it is a collection of secondary data.
Conclusions: It was possible to identify that the "Good labor assistance practices" has been developed in a good proportion considered; however some practices that should be discouraged are still performed relatively frequently.
Characterization of People with Diabetes Mellitus Assisted in an Outpatient Follow-up Clinic
Authors: Oliveira Patrícia Simplício de , Lima Carla Lidiane Jácome de , Ferreira Josefa Danielma Lopes , Ferreira Thalys Maynnard Costa , Lucena Adriana Lira Rufino de , Acioly Cizone Maria Carneiro , Agra Glenda , Cruz Ronny Anderson de Oliveira , Silva Maryjane Alves Oliveira da , Costa Marta Miriam Lopes 
Published: April 2017

Objective: To characterize the profile of people with diabetes, according to sociodemographic, clinical and laboratory variables.
Method: Cross-sectional study with a quantitative approach, conducted with 110 people with diabetes mellitus treated at outpatient follow-up of a teaching hospital in João Pessoa - PB, Brazil, during February-June 2015. To collect data, we used a form contemplating sociodemographic, clinical and laboratory variables. For the analysis, we used descriptive statistics often measures for categorical variables, mean and standard deviation for numeric variables.
Results: The study revealed that the socio-demographic, clinical and laboratory characteristics increase the risk of morbidity and mortality for people studied, as well as being impediments to the realization of self-care.
Conclusion: The importance of achieving education for self-care was evident, for many of these identified factors can be modified when the person with diabetes has knowledge about their health-disease process, promoting positive attitudes in their care.
A 22nd case report of extrauterine adenomyoma of the abdominal wall
Authors: Sampaio Rita , Palla Garcia José , Macedo Carlos Sampaio , Vizcaíno José Ramón 
Published: April 2017

An adenomyoma of the uterus is a nodular tumor-like mass of benign endometrial glands, endometrioid stroma and smooth muscle tissue. Extra-uterine adenomyoma is an extremely rare tumor. The majority of the cases described was from ovary and located in the pelvis. We present a case of a 70 years old woman with clinical and radiological suspicious of disseminated malignancy. In the abdominal wall, a 5-cm nodule of larger dimension detected by computed tomography-scan was biopsied for accessibility reasons. The morphological and immunohistochemical features of the biopsy led us to propose the diagnosis of an extrauterine adenomyoma. This article reports the 22nd case of extrauterine adenomyoma, a rare and poorly understood tumor that could be imagiologically and clinically indistinguishable from a metastasis.
Acute Myeloid Leukemia Clinical Practice Guidelines in Oncology
Authors: _ _ 
Published: April 2017

Approximately 11,960 people will be diagnosed with acute myeloid leukemia (AML) in 2005, and 9,000 patients will die of the disease. As the population ages, the incidence of AML, along with myelodysplasia, appears to be rising. Equally disturbing is the increasing incidence of treatment-related myelodysplasia and leukemia in survivors of tumors of childhood and young adulthood such as Hodgkin's disease, sarcomas, breast and testicular cancers, and lymphomas. Recent large clinical trials have highlighted the need for new, innovative strategies because outcomes for AML patients, particularly older patients, have not substantially changed in the past 3 decades.
For the most recent version of the guidelines, please visit NCCN.org
Myelodysplastic Syndromes Clinical Practice Guidelines in Oncology
Authors: _ _ 
Published: April 2017

The myelodysplastic syndromes (MDS) represent myeloid clonal hemopathies with relatively heterogeneous spectrums of presentation. The major clinical problems in these disorders are morbidities caused by patients' cytopenias and the potential for MDS to evolve into acute myeloid leukemia (AML). Managing MDS is complicated by the generally advanced age of the patients (median ages range from 65–70 years), the attendant non-hematologic comorbidities, and older patients' relative inability to tolerate certain intensive forms of therapy. In addition, when the illness progresses into AML, these patients experience lower response rates to standard therapy than patients with de novo AML.
For the most recent version of the guidelines, please visit NCCN.org
Neuroendocrine Tumors Clinical Practice Guidelines
Authors: _ _ 
Published: April 2017

Neuroendocrine tumors are relatively rare. An estimated 25,690 new cases of thyroid cancer will be diagnosed in the United States in 2005, accounting for approximately 1% of all malignancies. Neuroendocrine tumors can be broadly subdivided into tumors that are benign or malignant, functional (i.e., producing a syndrome of hormonal excess) or nonfunctional. The management of neuroendocrine tumors with surgical, medical, or radiation therapies is determined by the specific endocrine glands involved, aggressiveness and stage of the tumor, hormonal concentrations detected, and specific patient needs. These guidelines have been designed to address scenarios presented by 80% of patients and to avoid scenarios relevant to less than 5% of patients.
For the most recent version of the guidelines, please visit NCCN.org
Non-Hodgkin's Lymphoma Clinical Practice Guidelines
Authors: _ _ 
Published: April 2017

Non-Hodgkin's lymphomas (NHLs) may be classified on the basis of morphology, natural history, and immunophenotypic and molecular characteristics. These guidelines were developed for more common NHL histologic types, including chronic lymphocytic leukemia/small lymphocytic lymphoma, follicular lymphoma, and diffuse large B-cell lymphoma, and for less common entities with unique natural histories and therapies, such as marginal zone lymphoma, mantle cell lymphoma, and highly aggressive lymphoma subtypes, including Burkitt's, and lymphoblastic lymphomas and AIDS-related B-cell lymphomas. Certain components of the diagnosis and therapy of the various NHLs are similar. In all cases, an accurate pathologic diagnosis must first be made.
For the most recent version of the guidelines, please visit NCCN.org
Colorectal Cancer Screening Clinical Practice Guidelines
Authors: _ _ 
Published: April 2017

Colorectal cancer is the third most frequently diagnosed cancer in men and women in the United States. An estimated 104,950 new cases of colon cancer and 40,340 new cases of rectal cancer will occur in the United States in 2005. During the same year, an estimated 56,290 people will die from colon and rectal cancer. Because patients with localized colon cancer have a 90% 5-year survival rate, screening is a critical and particularly effective procedure for colorectal cancer prevention. Screening options include colonoscopy; combined fecal occult blood test (FOBT) and sigmoidoscopy; sigmoidoscopy alone; or double-contrast barium enema.
For the most recent version of the guidelines, please visit NCCN.org
Palliative Care
Authors: _ _ 
Published: April 2017

Over the past 20 years, increasing attention has been paid to quality-of-life issues in oncology. As the hospice movement has grown in this country, palliative care has developed into an integral part (rather than the antithesis) of comprehensive cancer care. Palliative care must be integrated earlier into the continuum of cancer care, and palliative, symptom-modifying therapy should be provided simultaneously with disease-modifying therapy from diagnosis. The goal of the NCCN palliative care guidelines is to help assure that each patient with cancer experiences the best possible quality of life throughout the illness trajectory. These guidelines are intended to help oncology teams provide the best care possible for their patients with incurable cancer.
For the most recent version of the guidelines, please visit NCCN.org
Venous Thromboembolic Disease
Authors: _ _ 
Published: April 2017

Venous thromboembolic disease is a common and life-threatening condition in cancer patients. Results from a recent retrospective study of 66,106 hospitalized adult neutropenic cancer patients showed that 2.74% to 12.10% of these patients, depending on the type of malignancy, experienced a venous thromboembolism (VTE) during first hospitalization. These guidelines specifically outline strategies to prevent and treat VTE in adult inpatients with either a diagnosis of cancer or for whom cancer is clinically suspected. These guidelines evaluate the therapeutic advantages of implementing pharmacologic anticoagulation measures based on both the perceived risk for bleeding (i.e., contraindications to anticoagulation) and the status of the cancer.
For the most recent version of the guidelines, please visit NCCN.org