bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heteroatom Doping Combined with Microstructured Carbon to Enhance the Performance of Sodium‐Ion Batteries
Authors: Liu Yang , Gao Zhiqiang 
Published: September 2016

AbstractA simple and effective procedure for the synthesis of nitrogen (N) and sulfur (S) co‐doped carbon accompanied by the formation of favorable microstructure is developed. The synthesized N and S co‐doped carbon materials are thoroughly investigated by electron microscopy, X‐ray diffractometry, X‐ray photoelectron spectroscopy, and nitrogen adsorption measurements. When applied as anodes in sodium‐ion batteries, high sodium storage capacities and excellent cyclic stability are obtained. It is observed that the contents of N and S atoms and the microstructure of the carbon have a significant effect on the performance of sodium‐ion battery. Under optimized synthetic conditions, the N and S co‐doped carbon materials have a specific capacity of 287.2 mA h g−1 in the second cycle and a stable specific capacity of 232.6 mA h g−1 even after 500 cycles at 0.5 A g−1. Moreover, the simple and facile procedure can be conventionally adopted for the preparation of other heteroatom‐doped carbon materials.
High‐performance Li‐ion Battery based on Cr‐Substituted Lithium Manganite and Lithium Titanate Spinels: Influence of Mass Balance on its Electrochemistry
Authors: Aklalouch Mohamed , Amarilla José Manuel , Rojo José María , Solhy Abderrahim , Rojas Rosa María , Saadoune Ismael 
Published: September 2016

AbstractThe influence of mass balance in the LiCr0.2Ni0.4Mn1.4O4//Li4Ti5O12 (LCrNMO//LTO) full cell on its electrochemical performance at different rates is described. The effect of the variation of the molar fraction of LTO to LCrNMO (χ) at different rates is described in detail. The full cell showed a reversible working potential at about 3 V. For every rate tested, the discharge capacity, normalized to total mass of both electrode materials (Qdch), reached a maximum value approximately at the stoichiometric value of χ=1. When χ<1, Qdch is limited by an incomplete electrochemical reaction of the LCrNMO cathode and when χ>1 Qdch decreases due to the increase in the total weight of active electrode materials. When the discharge rates were increased to ≥1 C (1 C=147.5 mA g−1 or 0.260 mA cm−2), the maximum Qdch delivered by the full cell was shifted slightly beyond the stoichiometry (χ=1.1). Furthermore, the LCrNMO//LTO full cell exhibited an outstanding ultralong cycling behavior: with a capacity retention of 93 % after 1000 cycles. Its cyclability is as high as 99.994 %. The LiCrNMO//LTO full cell is a promising lithium‐ion battery for practical applications, especially for plug‐in hybrid electric vehicles, for which a long cycle life and reasonable power are required. However, it is demonstrated that the optimization of anode to cathode materials is one of the most important parameters to take into account to achieve high energy and power densities.
Doctor Knows Best? Tubal Ligation in Young, Childless Women
Authors: Goldrath Kathryn , Smith Lauren B. 
Published: September 2016

AbstractWhen a gynecologist asks a twenty‐one‐year‐old patient about her use of contraception, he is surprised that she would like to have a tubal ligation. The patient says that she would “never want to bring a child into this screwed up world.” She has discussed tubal ligation with her boyfriend of one year, and he has told her that he accepts her decision. She asks her doctor if she can schedule the procedure as soon as possible. Her gynecologist mentions that he is concerned that she is very young and may eventually change her mind about having children. She insists that she has thought about it carefully and is certain that she wants the procedure. Her doctor feels very uncomfortable about this request. He consults the hospital ethics committee. Should he do as the patient asks or suggest that she wait at least six months and reconsider?
Leveling the Playing Field: Closing the Gap in Public Awareness of Genetics between the Well Served and Underserved
Authors: Kung Johnny , Wu Chao‐Ting 
Published: September 2016

AbstractThe impact of genetic technologies is being felt in many aspects of society, including medicine and the legal system, as well as the personal lives of individuals. How do we make sure that all segments of the population are equally aware of these technologies and have ample opportunity to voice opinions and shape the future? One ongoing effort, which began ten years ago and in which we are directly involved, is the Personal Genetics Education Project, a nonprofit initiative housed within and largely supported by the Department of Genetics at Harvard Medical School. The goal of pgEd is to raise public awareness and promote conversations about the benefits and implications of the genetics revolution in ways that are inclusive of all voices regardless of socioeconomic, educational, ethnic, cultural, or religious background. This essay describes our approach and experience in hopes that they will be of help to others engaged in similar efforts.
Do We Count?
Authors: Capron Alexander M. 
Published: September 2016

AbstractIn the article “A Conceptual Model for the Translation of Bioethics Research and Scholarship,” Debra Mathews and her colleagues want to apply to bioethics various translational concepts developed for biomedical research. According to experts in translational science, this would mean evaluating not only the extent to which research produces the “changes in thinking, practice, and policy” that interest Mathews et al. but also the appropriateness of bioethics training and the level of competency of people working in the field. Their proposal thus raises two sets of questions. The first, which the authors recognize must be the starting point for their argument, is, what precisely is the field in question? The second is whether the tools of translational science provide the right means of measuring the achievements of bioethics.
What Is Bioethics Worth?
Authors: Solomon Mildred Z. 
Published: September 2016

AbstractWhat is bioethics to do when it strives to assess the quality of its research and scholarship and when it needs to justify its work to prospective funders, especially a funder like the National Institutes of Health that privileges empirical discovery? In “A Conceptual Model for the Translation of Bioethics Research and Scholarship,” Debra Mathews and colleagues take an important first step at advancing an answer. The authors describe what they call a translational process, whereby bioethics “outputs” are translated into changes of three types: in thinking, practice, and policy. It goes nearly without saying that bioethics research and scholarship must be held accountable for changes in thinking. What raison d'etre do we have if not to deepen thinking, question assumptions, and encourage ourselves and others to examine hard issues from novel approaches? Assuredly it is hard to assess quality, and even harder to assess specific changes in thinking for which high‐quality scholarship may be responsible, but it is a necessary goal and one for which we should strive without reservation. Bioethics should also affect policy and practice. We should document how it does and the extent to which it does as often and as prominently as possible. However, let us be wary of pinning too much on practice and policy changes as the primary way of establishing bioethics’ worth.
Cultivating Synergy in Nursing, Bioethics, and Policy
Authors: Grady Christine 
Published: September 2016

AbstractNursing and bioethics have a lot in common because they share concerns about life and death, illness and health, the rights of individuals and communities, ethical patient care, health care delivery, and public health. Nurses and bioethicists contribute to ethical practice, ethics scholarship, and health policy‐making in a variety of ways. Some nurses have bioethics education or experience, some bioethicists study or collaborate closely with nurses, and some of us proudly identify as both bioethicists and as nurses. Despite certain shared and interwoven aims, bioethicists and nurses often accomplish their goals in dissimilar ways, have diverse educational and training trajectories as well as distinct roles and responsibilities, and are viewed differently within health care organizations. Yet the work of bioethics and nursing can be, and in my view should more often be, synergistic. That synergism may be especially critical in the arena of health policy and ethics. Nurses can bring extraordinary insights and real‐world experiences to the policy table but are not always considered essential contributors.
Nursing's Code of Ethics, Social Ethics, and Social Policy
Authors: Fowler Marsha D. 
Published: September 2016

AbstractModern American nursing arose during the Civil War and subsequently adopted the Nightingale educational model in the 1870s. By 1889, the journal Trained Nurse and Hospital Review had been established. It published a six‐part series on ethics in nursing. With the establishment of the American Nurses Association in 1893, the articles of incorporation gave the organization its first charge: “to establish and maintain a code of ethics.” While the rich and enduring tradition of nursing's ethics has been concerned about individual patients and their relational nexus, nursing ethics has from the beginning been a social ethics, intimately concerned both for the shape of society and for social change. This concern has been for health, conceived broadly and not focused specifically on disease and its treatment, but including the social causes of disease. Nightingale herself was an ardent social reformer, instituting a wide range of types of army sanitation reform, sanitation reform in India, and hospital and nursing reform. Despite her gender, her wealth and privilege granted her access to men in power who furthered her policy and reform agenda. From the start, then, modern nursing was imbued with a social reformist bias.
The Nurse as the Patient's Advocate: A Contrarian View
Authors: Shannon Sarah E. 
Published: September 2016

AbstractAn important role for all health care professionals is to be an advocate for their patients, and there is no question that many patients need advocacy to reach their health care goals. The role of advocate takes many forms, but one is to speak up when one is concerned for the safety or well‐being of a patient. A nurse is often the member of a health care team most likely to notice changes that might signal problems or poor responses to treatment. The duty of the nurse is to speak up in a timely and urgent manner when the nurse believes—or fears—that the patient's safety may be at risk. Yet the role of nurses as advocates for their patients has assumed near‐mythic status. Rather than seeing advocate as one among many equally important and interrelated professional roles, the nurse, when asked, “Who are you?” is likely to give the heartfelt and passionate answer, “The patient's advocate!” This essay examines and critically analyzes the advocacy role adopted by the nursing profession and outlines the challenges it has created to nursing's contributions to collaborative practice, ethics, and policy in health care.
Promoting the Health of Families and Communities: A Moral Imperative
Authors: Mason Diana J. 
Published: September 2016

AbstractThe Hill Burton Act, which was signed into law in 1946 and ended in 1997, was one of the most significant forces that shaped the health care system we have today. Providing grants and loans for the construction and expansion of hospitals across the country, it required beneficiary hospitals to give some amount of uncompensated care to the poor and uninsured in return.The act not only led to our health care system's current emphasis on the acute‐care hospital as the primary site of health care delivery, but it also had a profound effect on nursing, fully involving the profession in an acute‐care world. The act created jobs for nurses at an unprecedented level. There are over 3.4 million nurses in the United States, and in 2013, 63 percent of all nurses worked for hospitals. Nursing education continues to emphasize acute care, despite the calls for shifting the curriculum to more community‐based content and experiences that focus on health promotion and wellness for individuals, families, and communities. It is my premise that the nursing profession and all who profess to be committed to promoting health have a moral obligation to help the nation adopt a Hill‐Burton Act of the twenty‐first century that will focus on building healthy communities, supporting families in ways that promote health, and helping individuals to live healthier lives. This would require a shift in resources from a costly health care system to investing in community development, whether job creation, building safe places to play and exercise, providing access to affordable and nutritious foods, advancing the quality of education, or other approaches to addressing and improving the social determinants of health. Making this kind of investment would speak to the principles of beneficence, least harm, and justice, particularly for socioeconomically stressed communities.
Amplification and protein overexpression of cyclin D1: Predictor of occult nodal metastasis in early oral cancer
Authors: Noorlag Rob , Boeve Koos , Witjes Max J. H. , Koole Ronald , Peeters Ton L. M. , Schuuring Ed , Willems Stefan M. , van Es Robert J. J. 
Published: September 2016

AbstractBackgroundAccurate nodal staging is pivotal for treatment planning in early (stage I–II) oral cancer. Unfortunately, current imaging modalities lack sensitivity to detect occult nodal metastases. Chromosomal region 11q13, including genes CCND1, Fas‐associated death domain (FADD), and CTTN, is often amplified in oral cancer with nodal metastases. However, evidence in predicting occult nodal metastases is limited.MethodsIn 158 patients with early tongue and floor of mouth (FOM) squamous cell carcinomas, both CCND1 amplification and cyclin D1, FADD, and cortactin protein expression were correlated with occult nodal metastases.ResultsCCND1 amplification and cyclin D1 expression correlated with occult nodal metastases. Cyclin D1 expression was validated in an independent multicenter cohort, confirming the correlation with occult nodal metastases in early FOM cancers.ConclusionCyclin D1 is a predictive biomarker for occult nodal metastases in early FOM cancers. Prospective research on biopsy material should confirm these results before implementing its use in routine clinical practice. © 2016 Wiley Periodicals, Inc. Head Neck 39: 326–333, 2017
3‐Hz subthreshold oscillations of CA2 neurons In vivo
Authors: Matsumoto Nobuyoshi , Okamoto Kazuki , Takagi Yuki , Ikegaya Yuji 
Published: September 2016

ABSTRACTThe CA2 region is unique in the hippocampus; it receives direct synaptic innervations from several hypothalamic nuclei and expresses various receptors of neuromodulators, including adenosine, vasopressin, and oxytocin. Furthermore, the CA2 region may have distinct brain functions, such as the control of instinctive and social behaviors; however, little is known about the dynamics of the subthreshold membrane potentials of CA2 neurons in vivo. We conducted whole‐cell current‐clamp recordings from CA2 pyramidal cells in urethane‐anesthetized mice and monitored the intrinsic fluctuations in their membrane potentials. The CA2 pyramidal cells emitted spontaneous action potentials at mean firing rates of ∼0.8 Hz. In approximately half of the neurons, the subthreshold membrane potential oscillated at ∼3 Hz. In two neurons, we obtained simultaneous recordings of local field potentials from the CA1 stratum radiatum and demonstrated that the 3‐Hz oscillations of CA2 neurons were not correlated with CA1 field potentials. In tetrodotoxin‐perfused acute hippocampal slices, the membrane potentials of CA2 pyramidal cells were not preferentially entrained to 3‐Hz sinusoidal current inputs, which suggest that intracellular 3‐Hz oscillations reflect the neuronal dynamics of the surrounding networks. © 2016 Wiley Periodicals, Inc.
Early cognitive decline in older adults better predicts object than scene recognition performance
Authors: Fidalgo Celia O. , Changoor Alana T. , Page‐Gould Elizabeth , Lee Andy C. H. , Barense Morgan D. 
Published: September 2016

ABSTRACTThere is an ongoing debate regarding the nature of memory deficits that occur in the early stages of mild cognitive impairment (MCI). MCI has been associated with atrophy to regions that process objects, namely perirhinal and lateral entorhinal cortices. However, it is currently unclear whether older adults with early MCI will show memory deficits that are specific to objects, or whether they will also show memory deficits for other stimulus classes, such as scenes. We tested 75 older adults using an object and scene recognition task with stimulus‐specific interference (i.e., exposure to irrelevant object or scene stimuli). We found an interaction (P = 0.05) whereby scores on the Montreal Cognitive Assessment, a neuropsychological test with high sensitivity to MCI, shared a stronger relationship with object recognition than with scene recognition performance. Interestingly, this relationship was not modulated by the stimulus category of interfering items. To further explore these findings, we also tested an amnesic patient (DA) with known medial temporal lobe damage. Like older adults with early signs of MCI, DA showed poorer object recognition than scene recognition performance. Additionally, his performance was not modulated by the stimulus category of interfering material. By demonstrating that object memory is more predictive of cognitive decline than scene memory, these findings support the notion of perirhinal and lateral entorhinal cortex dysfunction in the early stages of MCI. © 2016 Wiley Periodicals, Inc.
NPS Pollution Reduction from Alpine Fields using Surface Cover Material and Soil Amendments
Authors: Won Chulhee , Shin Minhwan , Lee Suin , Park Younshik , Lee Youngjoon , Shin Yongchul , Choi Joongdae 
Published: September 2016

AbstractWe described the effects of straw mat cover and soil amendments on runoff, agricultural non‐point source nNPS) pollution and crop yield on sloping alpine fields in Korea. Two sandy loam field plots were prepared. One was a control plot and the other (SPG) was an experimental plot treated with rice straw, polyacrylamide (PAM) and gypsum (rice straw mat (3,300 kg/ha) + PAM (5 kg/ha) + gypsum (1 ton/ha)). Chinese cabbage was cultivated in the plots and seven rainfall‐runoff events were monitored during the growing season in 2012. Less runoff and a lower NPS pollution load were measured from the SPG plot, compared to those from the control plot. The SPG plot had 29.4% less runoff and the pollution load was reduced by 86.6% for suspended solids, 34.7% for total nitrogen and 39.1% for total phosphorus. The Chinese cabbage yield at the SPG plot was 39,600 kg/ha, which was about 40% higher than that at the control plot. These results indicated that the SPG treatment could not only reduce runoff and agricultural NPS pollution but also increase crop yield and be a best management practice for sandy loam sloping fields in Korea. © 2016 The Authors. Irrigation and Drainage Published by John wiley & Sons Ltd.
Silicification of the medial tooth in the blue crab Callinectes sapidus
Authors: Nesbit Katherine T. , Roer Robert D. 
Published: September 2016

ABSTRACTObservations of cuticular structures mineralized with silica within the Crustacea have been limited to the opal teeth of copepods, mandibles of amphipods, and recently the teeth of the gastric mill in the blue crab Callinectes sapidus. Copepod teeth are deposited during premolt, with sequential elaboration of organic materials followed by secretion of silica into the tooth mold. The timing of mineralization is in stark contrast to that of the general integument of crustaceans in which calcification is completely restricted to the postmolt period. To determine the timing of molt‐related deposition and silicification of the teeth of the gastric mill, the medial tooth of the blue crab C. sapidus was examined histologically and ultrastructurally across the molt cycle. Histological data revealed deposition of the organic matrix of the epicuticle and exocuticle during premolt. No evidence of postmolt changes in the thickness of the epicuticle and exocuticle, or any deposition of endocuticle, was observed. Scanning electron microscopy revealed degradation of the outer surface of the old tooth during premolt. During premolt, epithelial structures resembling papilla appeared to secrete a fibrous web that coalesces to become the matrix of the new tooth. Semi‐quantitative elemental analyses indicated simultaneous deposition of silica and organic matrix, and demonstrated a homogeneous distribution of silicon throughout the epicuticle of the tooth at all stages. However, there is evidence of deposition (presumably silicification) during postmolt as spaces between the papillae become filled in. Thus, the pattern and timing of deposition and silicification of the tooth are different from both teeth of copepods and the general exoskeleton of decapods, and may facilitate rapid resumption of feeding and consumption of the exuvia in early postmolt. J. Morphol. 277:1648–1660, 2016. © 2016 Wiley Periodicals, Inc.
New perspectives on ACL injury: On the role of repetitive sub‐maximal knee loading in causing ACL fatigue failure
Authors: Wojtys Edward M. , Beaulieu Mélanie L. , Ashton‐Miller James A. 
Published: September 2016

ABSTRACTIn this paper, we review a series of studies that we initiated to examine mechanisms of anterior cruciate ligament (ACL) injury in the hope that these injuries, and their sequelae, can be better prevented. First, using the earliest in vitro model of a simulated single‐leg jump landing or pivot cut with realistic knee loading rates and trans‐knee muscle forces, we identified the worst‐case dynamic knee loading that causes the greatest peak ACL strain: Combined knee compression, flexion, and internal tibial rotation. We also identified morphologic factors that help explain individual susceptibility to ACL injury. Second, using the above knee loading, we introduced a possible paradigm shift in ACL research by demonstrating that the human ACL can fail by a sudden rupture in response to repeated sub‐maximal knee loading. If that load is repeated often enough over a short time interval, the failure tended to occur proximally, as observed clinically. Third, we emphasize the value of a physical exam of the hip by demonstrating how limited internal axial rotation at the hip both increases the susceptibility to ACL injury in professional athletes, and also increases peak ACL strain during simulated pivot landings, thereby further increasing the risk of ACL fatigue failure. When training at‐risk athletes, particularly females with their smaller ACL cross‐sections, rationing the number and intensity of worst‐case knee loading cycles, such that ligament degradation is within the ACL's ability to remodel, should decrease the risk for ACL rupture due to ligament fatigue failure.© 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:2059–2068, 2016.