bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studiedag ‘Gezinstransities vanuit het perspectief van de kinderen’
Authors: Cerulus Ulrike , Mol Charlotte 
Published: May 2016

Studiedag ‘Gezinstransities vanuit het perspectief van de kinderen’
Op 29 september 2015 werd te Antwerpen een studiedag georganiseerd getiteld, ‘Gezinstransities vanuit het perspectief van de kinderen’. Aangezien tegenwoordig steeds meer kinderen opgroeien in een nieuw samengesteld gezin, rijst de vraag hoe kinderen deze nieuwe gezinssamenstelling ervaren en welke functies de verschillende betrokken professionals daarbij vervullen. Tijdens de studiedag stond deze vraag centraal en werd het ontstaan van een dergelijk nieuw samengesteld gezin na echtscheiding vanuit verschillende invalshoeken onderzocht. Daarbij werden de ervaringen met het ouderschapsplan in Nederland eveneens toegelicht, en dit vanuit juridisch en sociologisch standpunt. Vervolgens werden een aantal workshops georganiseerd waar onder meer de pedagogische ouderschapsbelofte met de opvoedingspiramide aan bod kwam, het juridische ouderschapsplan, het plusouderschapsplan, alsook de rol van magistraten in de familie- en jeugdrechtbanken. Tot slot vond een debat plaats tussen verschillende panelleden, zijnde prof. Frederik Swennen, mevrouw Nancy Bleys, raadgever Justitie bij het Vlaams Ministerie van Welzijn, de federaal minister van Justitie, Koen Geens en een jongerenvertegenwoordiger, Thomas van Grinsven.On September 29th 2015 a conference was held in Antwerp. The title of the conference was ‘Family transitions from the perspective of the children’. Because nowadays an increasing number of children grow up in newly recomposed families, questions arise concerning the influence of these newly recomposed families on the wellbeing of children who live in these families. Moreover, questions arise about the part which different professionals play within this context. The family recomposition and its impact were studied from different perspectives. Since the Netherlands has introduced an ‘ouderschapsplan’ (‘parenting plan’) some time ago, several findings on such plans were presented from a legal and a sociological perspective. Thereafter, workshops were organised which concerned de ouderschapsbelofte (‘the parental promise’), het juridische ouderschapsplan (‘the legal parenting plan’), het plusouderschapsplan (the ‘plus parenting plan’) and the role played by magistrates confronted with conflicts in the family court. Finally, a debate was held between prof. Frederik Swennen, the Flemish Minister of Welfare, Nancy Bleys, the federal Minister of Justice Koen Geens and Thomas Van Grinsven as a representative of the youth.
Mesenchymal Stromal Cell-Derived Extracellular Vesicles Protect the Fetal Brain After Hypoxia-Ischemia
Authors: Ophelders Daan R.M.G. , Wolfs Tim G.A.M. , Jellema Reint K. , Zwanenburg Alex , Andriessen Peter , Delhaas Tammo , Ludwig Anna-Kristin , Radtke Stefan , Peters Vera , Janssen Leon , Giebel Bernd , Kramer Boris W. 
Published: May 2016

Abstract

Preterm neonates are susceptible to perinatal hypoxic-ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic-ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential of systemically administered mesenchymal stromal cells (MSCs). The mechanism of MSC treatment is unclear but suggested to be paracrine, through secretion of extracellular vesicles (EVs). Therefore, we investigated in this study the protective effects of mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) in a preclinical model of preterm hypoxic-ischemic brain injury. Ovine fetuses were subjected to global hypoxia-ischemia by transient umbilical cord occlusion, followed by in utero intravenous administration of MSC-EVs. The therapeutic effects of MSC-EV administration were assessed by analysis of electrophysiological parameters and histology of the brain. Systemic administration of MSC-EVs improved brain function by reducing the total number and duration of seizures, and by preserving baroreceptor reflex sensitivity. These functional protections were accompanied by a tendency to prevent hypomyelination. Cerebral inflammation remained unaffected by the MSC-EV treatment. Our data demonstrate that MSC-EV treatment might provide a novel strategy to reduce the neurological sequelae following hypoxic-ischemic injury of the preterm brain. Our study results suggest that a cell-free preparation comprising neuroprotective MSC-EVs could substitute MSCs in the treatment of preterm neonates with hypoxic-ischemic brain injury, thereby circumventing the potential risks of systemic administration of living cells.

Significance
Bone marrow-derived mesenchymal stromal cells (MSCs) show promise in treating hypoxic-ischemic injury of the preterm brain. Study results suggest administration of extracellular vesicles, rather than intact MSCs, is sufficient to exert therapeutic effects and avoids potential concerns associated with administration of living cells. The therapeutic efficacy of systemically administered mesenchymal stromal cell-derived extracellular vesicles (MSC-EVs) on hypoxia-ischemia-induced injury was assessed in the preterm ovine brain. Impaired function and structural injury of the fetal brain was improved following global hypoxia-ischemia. A cell-free preparation of MSC-EVs could substitute for the cellular counterpart in the treatment of preterm neonates with hypoxic-ischemic brain injury. This may open new clinical applications for “off-the-shelf” interventions with MSC-EVs.
High nonpublication rate from publication professionals hinders evidence-based publication practices
Authors: Carey Luke C. , Stretton Serina , Kenreigh Charlotte A. , Wagner Linda T. , Woolley Karen L. 
Published: May 2016

Background.The need for timely, ethical, and high-quality reporting of clinical trial results has seen a rise in demand for publication professionals. These publication experts, who are not ghostwriters, work with leading medical researchers and funders around the world to plan and prepare thousands of publications each year. Despite the involvement of publication professionals in an increasing number of peer-reviewed publications, especially those that affect patient care, there is limited evidence-based guidance in the peer-reviewed literature on their publication practices. Similar to the push for editors and the peer-review community to conduct and publish research on publication ethics and the peer-review process, the International Society for Medical Publication Professionals (ISMPP) has encouraged members to conduct and publish research on publication planning and practices. Our primary objective was to investigate the publication rate of research presented at ISMPP Annual Meetings.Methods.ISMPP Annual Meeting abstract lists (April 2009–April 2014) were searched in November 2014 and data were extracted into a pilot-tested spreadsheet. MEDLINE was searched in December 2014 to determine the publication rate (calculated as the % of presented abstracts published as full papers in peer-reviewed journals). Data were analyzed using the Cochran-Armitage trend test (significance:P< .05) by an independent academic statistician.Results.From 2009 to 2014, there were 220 abstracts submitted, 185 accepted, and 164 presented. There were four corresponding publications (publication rate 2.4%). Over time, ISMPP’s abstract acceptance rate (overall: 84.1%) did not change, but the number of abstracts presented increased significantly (P= .02). Most abstracts were presented as posters (81.1%) and most research was observational (72.6%). Most researchers came from the US (78.0%), followed by Europe (17.7%), and the Asia-Pacific region (11.2%).Discussion.Research presented at ISMPP Annual Meetings has rarely been published in peer-reviewed journals. The high rate of nonpublication by publication professionals has now been quantified and is of concern. Publication professionals should do more to contribute to evidence-based publication practices, including, and especially, their own. Unless the barriers to publication are identified and addressed, the practices of publication professionals, which affect thousands of peer-reviewed publications each year, will remain hidden and unproven.
Implementation of the Anti-Red Tape Act of 2007 by the National Labor Relations Commission-Regional Arbitration Branch 10
Authors: Ua-O Amor Lea O. 
Published: May 2016

In response to the urgent need to fix corruption that has long plagued the nation, the Philippine government enacted on June 2, 2007 the Republic Act No. 9485, otherwise known, as the “Anti-Red Tape Act of 2007” (ARTA).The study evaluated the current situation of ARTA implementation of NLRC-RAB10 with regards to the formulation of its Citizen’s Charter and re-engineering of systems, as well as, discover the problems, strengths and weaknesses in the posting of Citizen’s Charter, the accessibility of frontline services, accountability of officials and employees, and physical working condition. It employed the descriptive design. Interview, survey questionnaires, and observations were the technique used in data gathering. The data were analyzed using percentage, frequency, mean, and standard deviation. The findings of the study revealed that there was no formulation of Citizen’s Charter that was effected in compliance with RA 9485 (ARTA law). Therefore, re-engineering of the agency’s systems and procedures was not implemented. Consequently, problems were identified by customers regarding the improper posting of Citizen’s Charter, accessing Frontline services, and the physical working conditions of the office. The suggested interventions were relevant in enhancing the ARTA implementation of NLRC-RAB10.It is recommended that officials and employees of NLRC-RAB10 must revisit the provision of RA 9485 and it’s Implementing Rules and strictly adheres to all the requirements stipulated under the law. Further, the agency must consider reengineering the physical lay-out of the office. Keywords - Social Sciences, anti-red tape, evaluation, NLRC-RAB10, descriptive design, Philippines
Trailblazing Transformative Accountability for High Performing Philippine Prosecutorial Services for the 21st century
Authors: Velasco Arthur S. 
Published: May 2016

This study is focused on the prosecution as a major service component of the criminal justice system and analyzes the changing role of prosecutors in light of the Philippine and global prosecutorial demands of the 21st century. This study employs an institutional development approach for strengthening the prosecutorial services from the traditional approach case processor to a proactive and cost-effective approach that could make prosecutors meet community demands in preventing crimes. Overall, the study will attempt to improve the National Prosecution Service (NPS) of the Philippines in terms of: (a) qualification, selection and training; (b) case handling; and (c) interaction with criminal justice actors. The study will further determine the involvement of the community in the successful prosecution of cases. Finally, the NPS will be able to make a design implement the community prosecution service in the Philippines during the 21st Century. Survey, group discussion, interview, and triangulation were done to answer the research problems. The survey questionnaires were gathered from the following respondents: prosecutors, judges, lawyers, probation officers and barangay officials. The result disclosed the need to improve the qualification, selection, and training; interaction with criminal justice actors; establish a better community partnership; establish information technology; and improve prosecutorial service outcome assessment in the Prosecutorial Service. It is recommended that a reform framework anchored on developmentally-oriented prosecutorial service, community prosecution be adopted and to update the law on NPS (P.D. No. 1275 as amended and R.A. No. 10071). Keywords - Civil Law, prosecution, transformative accountability, proactive, reactive, high performing reform index, descriptive research, Philippines
Resorts no Brasil: uma avaliação do desempenho
Authors: Bonfato Antonio Carlos , Baltieri Marcia Akemi Takahashi 
Published: May 2016

O presente artigo analisa o desempenho mercadológico e financeiro dos resorts no Brasil. O objetivo geral foi identificar o comportamento dos principais indicadores de desempenho financeiro, sob a ótica das receitas, na medida de contribuir para uma melhor compreensão de como opera esse setor no país. Para se obter os resultados desejados, foram realizadas pesquisas correlacionais que geraram os valores e índices de crescimento que permitiram estabelecer uma relação comparativa entre os anos de 2013 e 2014. Serviram como fontes primárias os resorts filiados à Associação Brasileira de Resorts - Resorts Brasil, bem como entrevista de campo, com profissional de reconhecida atuação na área. As fontes secundárias se basearam em autores consagrados no universo da temática analisada. O universo de investigação foi formado pelos 49 resorts oficialmente reconhecidos pela principal entidade da área no país, ABR/Resorts Brasil. A entidade colaborou com o presente estudo ao permitir o acesso ao de seu banco de dados, onde os associados depositam mensalmente as informações de desempenho. Os empreendimentos estudados também foram segmentados em quatro subgrupos que foram analisados de forma separada. Os resultados mostraram que o mercado de resorts nacionais segue avançando em seus índices de desempenho e aperfeiçoando seus processos internos de gestão e distribuição de vendas. Entre os anos analisados, foi observada uma melhora no desempenho das receitas nominais na ordem de 6,34% no principal índice analisado. No que tange aos subgrupos, os resorts localizados em praia e os que operam no sistema all inclusive geraram os resultados mais significativos.
Remote detection of water management impacts on evapotranspiration in the Colorado River Basin
Authors: Castle Stephanie L. , Reager John T. , Thomas Brian F. , Purdy Adam J. , Lo Min‐Hui , Famiglietti James S. , Tang Qiuhong 
Published: May 2016

AbstractThe complexity involved in accurate estimation and numerical simulation of regional evapotranspiration (ET) can lead to inconsistency among techniques, usually attributed to methodological deficiencies. Here we hypothesize instead that discrepancies in ET estimates should be expected in some cases and can be applied to measure the effect of anthropogenic influences in developed river basins. We compare an ensemble of corrected ET estimates from land surface models with Gravity Recovery and Climate Experiment and Moderate Resolution Imaging Spectroradiometer satellite‐based estimates in the intensively managed Colorado River Basin to contrast the roles of natural variability and human impacts. Satellite‐based approaches yield larger annual amplitudes in ET estimates than land surface model simulations, primarily during the growing season. We find a total satellite‐based ET flux of 142 ± 7 MAF yr−1 (175 ± 8.63 km3 yr−1), with 38% due to anthropogenic influences during summer months. We evaluate our estimates by comparison with reservoir storage and usage allotment components of the basin water management budget.
Copper‐Catalyzed Carbonylative Coupling of Cycloalkanes and Amides
Authors: Li Yahui , Dong Kaiwu , Zhu Fengxiang , Wang Zechao , Wu Xiao‐Feng 
Published: May 2016

AbstractCarbonylation reactions are a most powerful method for the synthesis of carbonyl‐containing compounds. However, most known carbonylation procedures still require noble‐metal catalysts and the use of activated compounds and good nucleophiles as substrates. Herein, we developed a copper‐catalyzed carbonylative transformation of cycloalkanes and amides. Imides were prepared in good yields by carbonylation of a C(sp3)−H bond of the cycloalkane with the amides acting as weak nucleophiles. Notably, this is the first report of copper‐catalyzed carbonylative C−H activation.
Stereoselective Arene‐Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides
Authors: Fäseke Vincent C. , Sparr Christof 
Published: May 2016

AbstractThe increasing awareness of the importance of amide atropisomers prompts the development of novel strategies for their selective preparation. Described herein is a method for the enantioselective synthesis of atropisomeric aromatic amides by an amine‐catalyzed arene‐forming aldol condensation. The high reactivity of the glyoxylic amide substrates enables a remarkably efficient construction of a new aromatic ring, which proceeds within minutes at ambient temperature to afford products with excellent stereoselectivity. The high rotational barriers of the reduced products highlight the utility of this stable, spatially organized chiral scaffold.
Finite‐Time Stabilization of Stochastic High‐Order Nonlinear Systems
Authors: Zhang Xing‐Hui , Zhang Kemei , Xie Xue‐Jun 
Published: May 2016

AbstractThis paper considers the problem of global finite‐time stabilization in probability for stochastic high‐order nonlinear systems in which the power order is greater than or equal to one and the drift and diffusion terms satisfy weaker growth conditions. Based on stochastic Lyapunov theorem on finite‐time stability, via the combined adding one power integrator and sign function method, constructing a
Lyapunov function and verifying the existence and uniqueness of solution, a continuous state feedback controller is designed to guarantee the closed‐loop system globally finite‐time stable in probability.
Entwicklung eines neuartigen vertikalen Teilungsbauwerks für Hochwasserentlastungen
Authors: Jensen Jürgen , Schmidt Jessica , Wieland Jörg 
Published: May 2016

AbstractInfolge des extremen Hochwasserereignisses an der Elbe im August 2002 kam es zu Beschädigungen und zur Überlastung der Hochwasserentlastungsanlage der Talsperre (TS) Malter sowie im Unterlauf zu massiven Überschwemmungen der Roten Weißeritz. Nach diesem katastrophalen Hochwasser wurden die Bemessungsabflüsse für die TS Malter überprüft und mussten deutlich erhöht werden. Die Leistungsfähigkeit der Hochwasserentlastungsanlage war für diese neuen Bemessungsabflüsse nicht mehr ausreichend. Die Landestalsperrenverwaltung des Freistaats Sachsen (LTV) hat dementsprechend die Erweiterung der Hochwasserentlastungsanlage geplant. Um die Überflutungssicherheit nach DIN 19700‐10 wiederherzustellen, wurde, auch aufgrund der Auflage des Denkmalschutzes, die alte Schussrinne zu erhalten, ein Konzept entwickelt, welches auch den Bau einer neuen, zweiten Schussrinne mit zusätzlichem neuem Tosbecken beinhaltet [1]. Die beiden Schussrinnen sollen über ein neuartiges Teilungsbauwerk mit einer vertikalen Strömungstrennung beaufschlagt werden. Um die Leistungsfähigkeit zu gewährleisten, wurde der Vorentwurf am Forschungsinstitut Wasser und Umwelt der Universität Siegen in einem physikalischen Modellversuch im Maßstab 1:25 überprüft und optimiert. Mit dem Modellversuch konnte u. a. die Geometrie des vertikalen Teilungsbauwerks so optimiert werden, dass mit der Umsetzung der Erweiterung der Hochwasserentlastungsanlage die Überflutungssicherheit der TS Malter wiederhergestellt werden kann.Development of a novel vertical diversion structure for spillways – Water engineering model tests for the Malter DamDue to the extreme flood event on the Elbe river in August 2002, there was damage and overloading of the spillway of the Malter Dam and massive flooding of the Rote Weißeritz. After this catastrophic Elbe flood event, the design discharges for the Malter Dam were significantly increased. The performance of the spillway was not sufficient for the new design discharges. The State Reservoir Administration of Saxony (LTV) has planned accordingly expanding the spillway. To restore the flood safety after DIN 19700‐10, a concept was developed, which also includes the construction of a new, second spillway chute with additional new stilling basin, also due to the restrictions of the Monument protection to obtain the old spillway chute [1]. Both spillways are to be applied by a new division structure with a vertical flow separation. To ensure the performance the preliminary draft of the expansion of the spillway was reviewed and optimized in a physical model test in 1:25 scale at the Research Institute Water and Environment of the University of Siegen. With the hydraulic model test could the geometry of the vertical diversion structure be optimized so that with the implementation of the expansion of the spillway the flooding safety of Malter Dam can be restored.
Zwangbeanspruchung von Stahlbetonbauteilen
Authors: Turner Katrin , Schlicke Dirk , Tue Nguyen Viet 
Published: May 2016

AbstractUm das tatsächliche Verhalten von Stahlbetonbauteilen unter vorwiegender Zwangbeanspruchung experimentell zu untersuchen, wurde an der Technischen Universität Graz ein neuer Versuchsaufbau konzipiert. Im Vordergrund steht hierbei die zusammenhängende Betrachtung der Spannungsgeschichte und Rissbildung, beginnend mit der erhärtungsbedingten Zwangbeanspruchung (früher Zwang) und der anschließenden Überlagerung mit weiteren Zwangbeanspruchungen in der Nutzungsphase (später Zwang).Ziel der experimentellen Untersuchung war es, die verbleibenden Zwangspannungen nach Spannungsrelaxation und Rissbildung zu quantifizieren sowie die Rissbreitenentwicklung im Nutzungszeitraum zu beobachten. Für den frühen Zwang wurde hierbei besonderes Augenmerk auf den Einfluss der realistischen Behinderungssituation (in der Regel teilweiser Zwang) und der thermischen Randbedingungen (insbesondere Auswirkungen thermischer Nachbehandlungsmaßnahmen) gelegt. Im späten Zwang fällt vor allem der Berücksichtigung des Bauteilzustands (Einzelriss oder abgeschlossenes Rissbild) eine entscheidende Rolle zu. Mit den Versuchsergebnissen kann gezeigt werden, dass die Effektivität von thermischen Nachbehandlungsmaßnahmen zur Vermeidung von Trennrissen sehr begrenzt ist und eine getrennte Betrachtung von frühem und spätem Zwang nicht immer zu einer sicheren Bemessung führt.Restrained Concrete Members – New Findings from Systematic Investigations with Restraint Frames for Reinforced ConcreteIn order to investigate the real structural behaviour of reinforced concrete members mainly subjected to restraint a new experimental set‐up was designed at the Graz University of Technology. In the focus of interest is the continuous investigation of the stress history and crack development starting with restraint due to hardening and the subsequent superposition with further deformation impacts during service life.The experimental investigation aims at quantifying the remaining restraint stresses after stress relaxation and crack formation as well as observing crack development during service life. In the hardening phase the influence of a realistic placement condition (normally partial restraint) and the thermal boundary conditions (especially thermal curing) was paid attention to. During service life the consideration of the member condition (single crack pattern or stabilized crack pattern) is highly significant.Based on the experimental results it can be concluded that thermal curing has only a limited influence on preventing through cracks and the separate consideration of early restraint and service life impacts does not always lead to design on the safe side.