bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: BETA‐AMINOKETONE 8. MITT. REGIOSPEZIFITAET DER SYNTHESE SUBSTITUIERTER 1‐METHYL‐3‐ACYL‐4‐HYDROXY‐PIPERIDINE DURCH CYCLISIERUNG SUBSTITUIERTER METHYL‐ UND PHENYL‐2‐(N‐METHYL‐N‐(2‐ACYLAETHYL)‐AMINO)‐AETHYLKETONE
Authors: BADOSOV E. P. , KHASIRDZHEV A. B. , GOLOBIN E. T. , UNKOVSKII B. V. 
Published: March 2016

AbstractBei Cyclisierungen der Aminodiketone (I) unter der Einwirkung von wäßrigem KOH bei 0‐25°C entstehen regiospezifisch die Piperidin‐Ketole (II).
ChemInform Abstract: SYNTHESIS OF BENZO(G)QUINOLINE DERIVATIVES PART 12, 1,2,3,4‐TETRAHYDRO‐4‐OXO‐10‐CHLOROBENZO(B)QUINOLINE
Authors: KOZYREVA N. P. , BEKHLI A. F. 
Published: March 2016

AbstractDie Chlorierung des Tetrahydro‐4‐0xmbenzochinolins (I) ergibt ein Monochlorderivat (II), das zur Identifizierung auch aus dem 1‐Chlor‐2‐naphthylamin (III) durch Umsetzung mit β‐Propiolacton (IV), Cyclisierung und Acetylierung hergestellt werden kann.
ChemInform Abstract: HETEROCYCLIC ANALOGS OF PLEIADIENE PART 16, NITRATION OF PERIMIDINE AND ITS 1‐ AND 2‐METHYL DERIVATIVES
Authors: POZHARSKII A. F. , KOROLEVA V. N. 
Published: March 2016

AbstractDie Nitrierung der Perimidine (I) mit Salpetersäure in Eisessig führt zu Gemischen der Mononitroderivate (II) und (III), deren Weitemitrierung drei Dinitroverbindungen (IV)‐(VI) liefert.
ChemInform Abstract: SYNTHESIS OF 4H‐1,3‐BENZOXAZIN‐4‐ONIUM SALTS AND OF 4H‐1,3‐BENZOXAZINE‐4‐ONES
Authors: RYABUKHIN YU. I. , MEZHERITSKII V. V. , DOROFEENKO G. N. 
Published: March 2016

AbstractDie Salicylamide (I) cyclisieren mit den Carbonsäureanhydriden (II) in Gegenwart von 70%iger Perchlorsäure zu Benzoxazinoniumsalzen (III), die mit Triäthylamin die Benzoxazinone (IV) ergeben und mit Wasser zu den N‐Acylsalicylamiden (V) hydrolysieren.
ChemInform Abstract: RING CONTRIBUTIONS TO THE PHOSPHORUS‐31 CHEMICAL SHIFTS OF TRANSITION METAL‐PHOSPHORUS CHELATE COMPLEXES
Authors: GARROU PHILIP E. 
Published: March 2016

AbstractEs werden die (31)P‐chemischen Verschiebungen für 40 Übergangsmetall‐Phosphor‐ Chelat‐Komplexe der Metalle Cr, Mo, W, Rn, Rh, Ir, Ni, Pd und Pt untersucht.
ChemInform Abstract: 1,1‐DIMETHYL‐1‐SILACYCLOHEXA‐2,4‐DIEN‐TRICARBONYLEISEN
Authors: FINK WALTER 
Published: March 2016

AbstractBei der Einwirkung von Fe(CO)5 clohexadien‐(2,4) (IIa) erfolgt bei Temperatu Dien (I).
ChemInform Abstract: NEUARTIGE ELIMINIERUNGSREAKTION AN KOHLENHYDRATEN, SYNTHESE DES METHYL‐4,6‐O‐BENZYLIDEN‐3‐DESOXY‐2‐O‐METHYL‐ALPHA‐D‐ERYTHROHEX‐2‐ENOPYRANOSIDS
Authors: KLEMER ALMUTH , RODEMEYER GUENTHER 
Published: March 2016

AbstractDas D‐Gluco‐ (Ia), D‐Altro‐ (Ib) und D‐Allohexopyranosid (Ic) reagieren jeweils unter Methanol‐Eliminierung zum Hexenopyranosid (II).
ChemInform Abstract: OLIGONUCLEOTIDE SYNTHESIS CATALYZED BY THE ZN(2+) ION
Authors: SAWAI HIROAKI , ORGEL LESLIE E. 
Published: March 2016

AbstractIn Gegenwart von Zn(2+) bildet Adenosin‐5′‐phosphorsäureimidazolid (ImpA) (I) in wäßriger Lösung neben dem üblichen Hydrolyseprodukt (II) das Imidazolid (III), die Oligoadenylsäuren (IV) und geringe Mengen an P1P2‐ Diadenosin‐5′‐pyrophosphat (V).
ChemInform Abstract: RATIONELLE SYNTHESE VON ALPHA‐L‐HOMOPROLIN UND EINIGER DERIVATE, DARSTELLUNG VON 7‐ALPHA‐L‐HOMOPROLIN‐BRADYKININ
Authors: BALASPIRI L. , PENKE B. , PAPP GY. , DOMBI GY. , KOVACS K. 
Published: March 2016

AbstractAus dem L‐Prolin (I) wurde über die Stufen (II)‐(V) α‐L‐Homoprolin (HPro) (VI) in optisch reiner Form synthetisiert.
ChemInform Abstract: SYNTHESES OF MACROLIDE ANTIBIOTICS PART 1, METHYMYCIN
Authors: MASAMUNE SATORU , KIM C. U. , WILSON KENNETH E. , SPESSARD GARY O. , GEORGHIOU PARIS E. , BATES GORDON S. 
Published: March 2016

AbstractDie seco‐Säure des Aglykons von Methymycin (I) wird durch Kondensation der Segmente A [C‐9 bis C‐11] (IIIb) und B [C‐1 bis C‐8] (XI) dargestellt.
ChemInform Abstract: A FLUOROMETRIC DETERMINATION OF ZINC IN PORTLAND CEMENT WITH 8‐QUINOLINETHIOL
Authors: WATANABE KUNIHIRO , KAWAGAKI KYOZO 
Published: March 2016

AbstractDie beschriebene Bestimmungsmethode stimmt mit den Ergebnissen der konventionellen Atomabsorptionsmethode gut überein.
ChemInform Abstract: ANODIC POLARIZATION BEHAVIOR OF HIGH‐PURITY 13 AND 18 PERCENT CR STAINLESS STEELS
Authors: LIZLOVS E. A. , BOND A. P. 
Published: March 2016

AbstractDie potentiodynamischen Polarisationskurven werden von dem im Titel genannten Edelstahl, der neben Cr noch Obis 5% Mo enthält, in In H2SO4 und ln HCl aufgenommen.
ChemInform Abstract: A STUDY OF THE ANODIZATION OF NIOBIUM USING THE METHOD OF OPEN‐CIRCUIT TRANSIENTS IN AQUEOUS AND NONAQUEOUS SOLUTIONS
Authors: DALY C. M. , KEIL R. G. 
Published: March 2016

AbstractDie anodische Oxidation von Nb wird in Eisessig‐Na‐tetraborat‐ und in wäßriger Borsäure‐Na‐tetraborat‐Lösung über einen Potentialbereich von 74 V untersucht.
ChemInform Abstract: ASYMMETRISCH STRUKTURIERTE MEMBRANEN. HERST. UND BEDEUTUNG
Authors: SAIER H.‐D. , STRATHMANN H. 
Published: March 2016

AbstractDer Fortschrittsbericht behandelt das Prinzip der Membranfiltration, die phänomenologische Beschreibung der Membran und der Membrantransportvorgänge, Membranmodelle, sowie Herstellung und Anwendung asymmetrischer Membranen.
ChemInform Abstract: THE QUANTUM YIELD OF PHOTOLYSIS OF WATER ON TIO2 ELECTRODES
Authors: OHNISHI T. , NAKATO Y. , TSUBOMURA H. 
Published: March 2016

AbstractDie Quantenausbeute der Photoströme in der elektrochemischen Zelle n‐TiO2/Elektrolyt/Pt wird bei monochromer Belichtung von TiO2 bei verschiedenen Elektrodenpotentialen gemessen.
ChemInform Abstract: CARBONYLATION OF STYRENE CATALYSED BY A PALLADIUM‐BIPHOSPHINE COMPLEX
Authors: SUGI Y. , BANDO K. , SHIN S. 
Published: March 2016

AbstractDie Carbonylierung von Styrol (V) in Äthanol durch den aus (I) und (II) zugänglichen Komplex (IIIa) liefert mit steigendem CO‐Druck (100 bis 300 at) und wachsendem Umsatz (45 bis 73 %) bevorzugt 3‐Phenyl‐propionsäure‐äthylester (VI).
ChemInform Abstract: EIGENSCHAFTEN BETA,GAMMA‐UNGESAETTIGTER SCHWEFELCARBANIONEN, DIE EINE METHYLSULFINYL‐GRUPPE IN ALPHA′‐STELLUNG TRAGEN, EINFL. DER TEMPERATUR AUF IHRE STABILITAET U. IHRE (2.3)SIGMATROPE UMLAGERUNG, NEUE SYNTH. EINES ALLYL‐VINYL‐SULFIDS UND EINES THIO‐ BZW. DITHIOAETHERS MIT VINYL‐GRUPPIERUNGEN
Authors: HUYNH CHANH HUYNH CHANH , RATOVELOMANANA VICTORIN , JULIA SYLVESTRE 
Published: March 2016

AbstractDas aus dem Isothiuroniumsalz (I) und dem Sulfoxid (II) zugängliche Sulfid" (III) wird mit Li‐diisopropylamid (Dial) in THF bei ‐65°C in das Carbanion (IV) übergeführt, aus dem über die Zwischenstufen (V) und (VI) das Derivat (VII) gewonnen wird.
ChemInform Abstract: ABSOLUTE CONFIGURATIONS AND CHIROPTICAL PROPERTIES OF OPTICALLY ACTIVE DERIVATIVES OF TRICYCLO(4.3.0.0(3,8))NONANE (′TWIST‐BRENDANE′)
Authors: NAKAZAKI MASAO , NAEMURA KOICHIRO , HARITA SIGEYUKI 
Published: March 2016

AbstractDas (+)‐endo‐Carboxybicycloocten (I) wird durch Reduktion mit LiAlH4 und nachfolgende Collins‐Oxidation über den Alkohol zum Aldehyd und anschließende Paterno‐ Büchi‐Photoringschlußreaktion in das (+)‐Oxetan (II) umgewandelt.
ChemInform Abstract: SALICYLOYL‐AMINOSAEURE‐ESTER UND ‐AMIDE
Authors: MAZZOTTA D. , GIORI P. , GUARNERI M. , BENASSI C. A. 
Published: March 2016

AbstractDurch Reaktion des Nitroso‐pyrazols (II) mit Acetyl‐salicylsäure (I) und Dicyclohexylcarbodümid erhält man den aktivierten Ester (III), der mit Aminosäureester (IV) zu den Salicyloyl‐aminosäureestern (V) reagiert.
ChemInform Abstract: 2.MITT. SYNTHESE VON P‐ALKYLSULFAMOYL‐THIOBENZAMIDEN UND EINIGEN DERIVATEN, IHRE AKTIVITAET IN VITRO AM STAMM H37RV DES TUBERKELBAZILLUS
Authors: COHEN VICTOR ISRAEL , RIST NOEL , CLAVEL SABINE 
Published: March 2016

AbstractDie Thioamide (Ia) und die Thioester (Ib) werden analog den Aryl‐Derivaten (siehe vorstehendes Referat) synthetisiert.
ChemInform Abstract: 3. MITT. SYNTHESE VON M‐ALKYL(ARYL)SULFAMOYL‐THIOBENZAMIDEN UND EINIGEN VERWANDTEN DERIVATEN, IHRE AKTIVITAET IN VITRO AM STAMM H37RV DES TUBERKELBAZILLUS
Authors: COHEN VICTOR ISRAEL , RIST NOEL , CLAVEL SABINE 
Published: March 2016

AbstractDie Titelverbindungen (Ia)‐(Ic) werden nach bekannten Methoden aus den entsprechenden m‐Alkyl(Aryl)sulfamoyl‐benzonitrilen dargestellt.
ChemInform Abstract: PREPARATION AND DETERMINATION OF ABSOLUTE ROTATIONS AND CONFIGURATIONS OF 6,7‐DIMETHOXY‐1,2‐DIMETHYL‐EXO‐2‐BENZONORBORNENYL DERIVATIVES
Authors: GOERING H. L. , BACKUS A. C. , CHANG C. S. , MASILAMANI W. 
Published: March 2016

AbstractAus 4,5‐Dimethoxy‐anthranilsäure (I) und Cyclopentadien (II) entsteht über das Dehydrobenzol das Addukt (III), aus dem das Keton (IV) erhalten wird.
ChemInform Abstract: SYNTHESE UND PHARMAKOLOGISCHE EIGENSCHAFTEN VON IN 2‐STELLUNG DURCH EINE SAEUREKETTE SUBSTITUIERTEN BENZOFURANCARBONSAEUREN
Authors: AUROZO ALAIN , FAURE ROBERT , MATTIODA GEORGES 
Published: March 2016

AbstractDie Titelverbindungen, z.B. (I)‐(V), werden nach bekannten Verfahren dargestellt: Die Benzofurancarbonsäure (Ia) nach Walker und Smith, (Ib) nach Andrisano und Duro.
ChemInform Abstract: 2‐PHENETHYLIMIDAZOLE DERIVATIVES. SYNTHESIS AND ANTIMYCOTIC PROPERTIES
Authors: GODEFROI E. F. , GEENEN J. J. H. , VAN KLINGEREN B. , VAN WIJNGAARDEN L. J. 
Published: March 2016

Abstract1,2‐Dimethyl‐imidazol (I) kann in Gegenwart von Triäthylamin in Acetonitril mit den Säurechloriden (II) zweifach zu den Enolestern (III) substituiert werden.
ChemInform Abstract: TETRAZOLE ANALOGUES OF PHENYLALANINES
Authors: BREWSTER KEITH , PINDER ROGER MARTIN 
Published: March 2016

AbstractAusgehend von den Nitrilen (Ic) ‐ erhältlich aus den Säuren (Ia) durch Dehydrierung ihrer Amide (Ib) ‐ werden entsprechende Tetrazole (II) dargestellt; nachfolgende Dephthaloylierung gibt die Phenylalanin‐Analogen (III) (Tetrazolyl ‐ anstelle einer Carboxylgruppe).
ChemInform Abstract: DIE DECKER‐OXIDATION 2‐SUBSTITUIERTER N‐ALKYLPYRIDINIUMVERBINDUNGEN 1. MITT. RK.‐VERHALTEN VON 1‐METHYL‐2‐ALKYL‐ UND 1‐METHYL‐2‐HYDROXYALKYLPYRIDINIUMSALZEN
Authors: WEBER H. 
Published: March 2016

AbstractDie Decker‐Methode der alkalischen Hexacyanoferrat(III)‐Oxidation der 2‐substituierten Pyridiniumverbindungen (I) liefert ausschließlich 1‐Methyl‐2‐pyridon (II).
ChemInform Abstract: COMPLEXES OF ORGANIC ARSONIC ACIDS WITH METAL IONS PART 5, COMPLEXES OF LA(III), ND(III) AND SM(III) WITH PHENYLARSONIC ACID AND ITS ORTHO‐ AND PARA‐SUBSTITUTED DERIVATIVES
Authors: SANDHU S. S. , AULAKH G. S. 
Published: March 2016

AbstractDie Titelverbindungen (I) wurden durch Rückflußkochen der Lanthanoidchloride mit den Phenylarsonsäuren in absolutem Äthanol dargestellt und durch IR‐Daten, Absorptionsmaxima und magnetische Momente charakterisiert.
ChemInform Abstract: SYNTHESE UND EIGENSCHAFTEN VON BIS‐AETHINYLVERBINDUNGEN DES SILICIUMS UND GERMANIUMS SOWIE DARAUS ENTSTEHENDE POLYMERE
Authors: LUNEVA L. K. , VASNEVA N. A. , SLADKOV A. M. , KORSHAK V. V. 
Published: March 2016

AbstractDihalogengermane oder Dihalogensilane wie (III) und (VI) reagieren mit Äthinylmagnesiumbromid (IV) zu Bis‐äthinylderivaten (V) bzw. (VII).
ChemInform Abstract: (MO6CL8)(OC6F5)4(HMPA)2, EINE FLUECHTIGE MOLYBDAENCLUSTERVERBINDUNG
Authors: ABEL HANS‐JUERGEN , RABENECK HELMUT , SCHAEFER HARALD 
Published: March 2016

AbstractDie Titelverbindung wurde durch Reaktion von MoöClz in CH2Cl2 mit Hexamethylphosphortriamid und Na‐perfluorphenolat in Wasser mit 91% Ausbeute dargestellt.
ChemInform Abstract: THE (13)C MAGNETIC RESONANCE STUDY ON THE EFFECTS OF DIVOLENT PARAMAGNETIC METALS ACETYLACETONATES ON PYRIDINE, QUINOLINE, AND ISOQUINOLINE. SPECIFIC INTERACTIONS WITH MN(AA)2
Authors: HAYAMIZU KIKUKO , MURATA MAKOTO , YAMAMOTO OSAMU 
Published: March 2016

AbstractDie Effekte der paramagnetischen Ni(II)‐, Co(II)‐, Cu(II)‐ oder Mn(II)‐acetylacetonate auf die (13)C‐chemischen Verschiebungen, Linienbreiten und Spingitter‐Relaxationszeiten von Pyridinlösungen werden untersucht.
ChemInform Abstract: THE KINETICS OF RING CLOSURE AND HYDROLYSIS OF A NUMBER OF HALO‐COBALT(III) COMPLEXES OF DIAMINOPOLYCARBOXYLATE LIGANDS
Authors: EVANS M. H. , GROSSMAN B. , WILKINS R. G. 
Published: March 2016

AbstractDie Kinetik der Reaktion der Komplexe (I), in denen die Tetraacetate als fünfzähniger Ligand fungieren, zu den Produkten (II), in denen alle sechs Donatoratome des Liganden koordiniert sind, wird untersucht.
ChemInform Abstract: SYNTHESIS OF 5ALPHA‐CHOLESTAN‐3‐METHYL‐3‐ACETALDEHYDE AND 5‐PREGNEN‐20‐METHYL‐3BETA‐OL‐16‐ONE
Authors: TREHAN I. R. , SHARMA DINESH K. , REWAL D. V. L. 
Published: March 2016

AbstractDer aus dem Nitril (I) erhältliche Aldehyd (III) setzt sich mit Li‐dimethyl‐cuprat (IV) zur Titelverbindung (V) um.
ChemInform Abstract: METHODISCHE UNTERSUCHUNGEN ZUR MERRIFIELD‐SYNTHESE 3. MITT. SYNTHESE DES SCHWEINE‐PROINSULIN‐(28‐34)‐HEPTAPEPTIDES NACH DER MERRIFIELD‐TECHNIK UND DURCH FRAGMENTKONDENSATION AM POLYMEREN TRAEGER
Authors: NEUBERT K. , JAKUBKE H.‐D. 
Published: March 2016

AbstractDie geschützte Teilsequenz (I) wird nach der schrittweisen Merrifield‐Technik sowie durch Fragmentkondensation (2 + 2 + 2 Verknüpfung) unter Verwendung der entsprechenden Boc‐Dipeptid‐5‐chlorchinolyl‐(8)‐ester am polymeren Träger synthetisiert.
ChemInform Abstract: SUCROSE CHEMISTRY PART 6, SYNTHESIS OF AMINO DERIVATIVES OF SUCROSE
Authors: SUAMI TETSUO , IKEDA TOSHIHIDE , NISHIYAMA SHIGERU , ADACHI RYOICHI 
Published: March 2016

AbstractAus der Heptaacetylsaccharose (Ia) wird nach üblichen Methoden über das Tosylat (Ib) das Azid (Ic) dargestellt, das durch Hydrogenolyse und nachfolgende Des‐O‐ acetylierung das 6′‐Desoxy‐6′‐amino‐Derivat (II) liefert.
ChemInform Abstract: PREPARATION AND PROPERTIES OF 5‐PHENYLPHENOXYMETHYLPENICILLIN
Authors: VANDERHAEGHE H. , THOMIS J. 
Published: March 2016

AbstractAus Azido‐acetylchlorid (I) erhält man in Gegenwart von Triäthylamin über das Keten mit den Thiazolinen (IIa)‐(IIc) die Addukte (III), die zu den Aminen (IV) reduziert werden.
ChemInform Abstract: M2PO3N (M: Ca, Sr): ortho‐Oxonitridophosphates with β‐K2SO4 Structure Type.
Authors: Marchuk Alexey , Schultz Peter , Hoch Constantin , Oeckler Oliver , Schnick Wolfgang 
Published: March 2016

AbstractCa2PO3N (I) and Sr2PO3N (II) are prepared by hot press sintering of stoichiometric amounts of PON and CaO or SrO (multianvil apparatus, 7 GPa, 1100 °C, 60 min) or by solid state reaction (N2‐filled silica tubes, 1100 °C, 2 h or 24 h, resp.).
ChemInform Abstract: Cobalt Clusters with Cubane‐Type Topologies Based on Trivacant Polyoxometalate Ligands.
Authors: Duan Yan , Clemente‐Juan Juan M. , Gimenez‐Saiz Carlos , Coronado Eugenio 
Published: March 2016

AbstractNa1.5Cs2.5 [Co4(OH)3(H2O)6 (PW9O34)]·9H2O (I) is obtained by reaction of Na(OAc), CoSO4, Na8H[PW9O34] (H2O, 80 °C, 20 min) followed by addition of CsCl (5% yield).
ChemInform Abstract: Phosphino‐amine (PN) Ligands for Rapid Catalyst Discovery in Ruthenium‐Catalyzed Hydrogen‐Borrowing Alkylation of Anilines: A Proof of Principle.
Authors: Broomfield Lewis Marc , Wu Yichen , Martin Eddy , Shafir Alexandr 
Published: March 2016

AbstractA series of simple phosphino‐amine ligands is synthesized and screened in aromatic amine alkylations via ruthenium‐catalyzed hydrogen borrowing reactions.
ChemInform Abstract: A Highly Efficient Mukaiyama—Mannich Reaction of N‐Boc Isatin Ketimines and Other Active Cyclic Ketimines Using Difluoroenol Silyl Ethers Catalyzed by Ph3PAuOTf.
Authors: Yu Jin‐Sheng , Zhou Jian 
Published: March 2016

AbstractCyclic ketimines (I), and active cyclic sulfonimines (VIII) undergo Mukaiyama—Mannich reactions with difluoroenol silyl ethers (II) catalyzed by title Au(I) complex affording cyclic compounds substituted by an α,α‐difluoroketone moiety.
ChemInform Abstract: Trimethylsilyloxide‐Catalyzed Peterson Olefinations with 2,2‐Bis(trimethylsilyl)‐1,3‐dithiane.
Authors: Manvar Atul , O'Shea Donal F. 
Published: March 2016

AbstractThe required title reagent (III) is readily available in one pot and excellent yield and can be applied with success to the olefination of a variety of aliphatic and aromatic aldehydes under either conditions A) or B).
ChemInform Abstract: One‐Pot Synthesis of N‐(α‐Peroxy)Indole/Carbazole via Chemoselective Three‐Component Condensation Reaction in Open Atmosphere.
Authors: Wang Xinbo , Pan Yupeng , Huang Kuo‐Wei , Lai Zhiping 
Published: March 2016

AbstractThe title compounds are prepared as potential building blocks for the synthesis of mycotoxins Fumitremorgin A and Verruculogen or their derivatives.
ChemInform Abstract: C—H Insertions in Oxidative Gold Catalysis: Synthesis of Polycyclic 2H‐Pyran‐3(6H)‐ones via a Relay Strategy.
Authors: Zheng Zhitong , Zhang Liming 
Published: March 2016

AbstractFunctionalized bicyclic or polycyclic pyranones are obtained by a cascade cyclization and subsequent C—H insertion starting from easily accessible bispropargyl ethers.
ChemInform Abstract: Efficient Access to Bicyclo[4.3.0]nonanes: Copper‐Catalyzed Asymmetric Silylative Cyclization of Cyclohexadienone‐Tethered Allenes.
Authors: He Zhi‐Tao , Tang Xiao‐Qi , Xie Li‐Bo , Cheng Mian , Tian Ping , Lin Guo‐Qiang 
Published: March 2016

AbstractA Cu‐catalyzed tandem process consisting of selective β‐silylation of the allene and subsequent enantioselective 1,4‐addition to the cyclohexadienone unit is developed.
ChemInform Abstract: Multicomponent Green Synthesis, Spectroscopic and Structural Investigation of Multi‐Substituted Imidazoles. Part 1.
Authors: Mohamed Shaaban K. , Simpson Jim , Marzouk Adel A. , Talybov Avtandil H. , Abdelhamid Antar A. , Abdullayev Yusif A. , Abbasov Vagif M. 
Published: March 2016

AbstractTetra‐substituted imidazole derivatives are obtained under solvent‐free and green reaction conditions by four‐component cyclocondensation of benzene, ethanolamine, various aromatic aldehydes, and ammonium acetate using the novel, reusable ionic liquid catalyst, diethylammonium hydrogen sulfate.
ChemInform Abstract: Highly Stereoselective Domino Oxa‐Michael/Aza‐Michael/Cyclization: Synthesis of Bicyclic Lactams and Spirooxindole Skeleton.
Authors: Le Goff Ronan , Sanselme Morgane , Lawson Ata Martin , Daich Adam , Comesse Sebastien 
Published: March 2016

AbstractBicyclic lactams such as (III) are readily available in the presence of 0.9‐1.2 equiv.
ChemInform Abstract: Non‐catalytic Multicomponent Rapid and Efficient Approach to 10‐(2,4,6‐Trioxohexahydropyrimidin‐5‐yl) ‐3,3‐dimethyl‐2,3,4,9‐tetrahydro‐1H‐xanthen‐1‐ones from Salicylaldehydes, Dimedone, and Barbituric Acids.
Authors: Elinson Michail N. , Nasybullin Ruslan F. , Sokolova Olga O. , Zaimovskaya Tatiana A. , Egorov Mikhail P. 
Published: March 2016

AbstractTitle compounds (IV) are efficiently and eco‐friendly synthesized within very short reaction times without the need of any catalyst.
ChemInform Abstract: Synthesis of Helquats Based on Phenanthridinium Units: Four‐Step Procedure to Novel Extended Helical Dications.
Authors: Sonawane Manoj R. , Vavra Jan , Saman David , Cisarova Ivana , Teply Filip 
Published: March 2016

AbstractStarting compound (I) is prepared in two steps from phenanthridin‐6‐one.
ChemInform Abstract: Palladium‐Catalyzed Regioselective Aerobic Oxidative Cyclization via C—H Activation in Chloroquine Analogues: Synthesis and Cytotoxic Study.
Authors: Senthil Kumar Gopal , Ali Mohamed Ashraf , Choon Tan Soo , Rajendra Prasad Karnam Jayarampillai 
Published: March 2016

AbstractThe new compounds are screened for their cytotoxic activities against CCRF‐CEM, HT29, and MCF7 human cancer cell lines.
ChemInform Abstract: Efficient Synthetic Access to Novel N‐(Pyrimidinyl)‐N‐(1H‐benzo[d]imidazolyl)amines in an Aqueous Medium.
Authors: Bonacorso Helio G. , Calheiro Tainara P. , Zanatta Nilo , Martins Marcos A. P. 
Published: March 2016

Abstractvia cyclocondensation of guanidine (I) with trifluoroalkenone derivatives (II)
ChemInform Abstract: Facile Synthesis of 4‐Aryl and Alkyl Substituted, N6‐Alkylated Pyridazine‐3,6‐diamines.
Authors: Wlochal Joanna , Bailey Andrew 
Published: March 2016

AbstractN‐unprotected substrate (I) undergoes Suzuki or Negishi coupling to afford 4‐aryl and 4‐alkyl substituted pyridazines.
ChemInform Abstract: NIS‐Catalyzed Oxidative Cyclization of Alcohols with Amidines: A Simple and Efficient Transition‐Metal Free Method for the Synthesis of 1,3,5‐Triazines.
Authors: Tiwari Abhishek R. , Akash T. , Bhanage Bhalchandra M. 
Published: March 2016

AbstractA wide range of 1,3,5‐triazines is efficiently synthesized via the title reaction of amidines (I) with benzyl alcohols under mild transition‐metal and phosphine free conditions without the need of oxygen in good yields.
ChemInform Abstract: Indole Alkaloids from the Sea Anemone Heteractis aurora and Homarine from Octopus cyanea.
Authors: Shaker Kamel H. , Goehl Matthias , Mueller Tobias , Seifert Karlheinz 
Published: March 2016

Abstractisolation of two new indole alkaloids (I) and (II) and confirmation of their structure by independent synthesis
ChemInform Abstract: Antimalarial and Antimycobacterial Agents from Streptomyces sp. BCC27095
Authors: Intaraudom Chakapong , Bunbamrung Nantiya , Dramae Aibrohim , Danwisetkanjana Kannawat , Rachtawee Pranee , Pittayakhajonwut Pattama 
Published: March 2016

Abstractisolation and biological evaluation of two new, compounds (I) and (II), and two known anthraquinone derivatives
ChemInform Abstract: Synthetic Design of TPEN Derivatives for Selective Extraction of Trivalent Minor Actinides Against Lanthanides
Authors: Miyazaki Yuji , Suzuki Shinichi , Kobayashi Toru , Yaita Tsuyoshi , Inaba Yusuke , Takeshita Kenji , Mori Atsunori 
Published: March 2016

AbstractReview: [17 refs.
Enhanced Efficacy of Artemisinin Loaded in Transferrin‐Conjugated Liposomes versus Stealth Liposomes against HCT‐8 Colon Cancer Cells
Authors: Leto Isabella , Coronnello Marcella , Righeschi Chiara , Bergonzi Maria Camilla , Mini Enrico , Bilia Anna Rita 
Published: March 2016

AbstractArtemisinin (ART) is a unique sesquiterpene lactone isolated from Artemisia annua that is well known for antimalarial properties and was recently reported as a promising anticancer drug. The aim of our work was to develop a novel nanocarrier for enhanced ART delivery and activation in cancer tissues, because transferrin receptors are largely expressed in cancer cells and the iron content is higher than in normal cells. ART was loaded in transferrin‐conjugated liposomes (ART‐L‐Tf), and the performance was compared with ART loaded in stealth liposomes (ART‐L). All of the liposomes were fully characterized in terms of size, drug‐entrapment efficiency, transferrin coupling moieties, and stability. Both cell uptake and cytotoxicity studies of the developed nanocarriers were tested in the HCT‐8 cell line, selected among several cell lines because of transferrin receptor overexpression. The results confirmed the enhanced delivery of ART‐L‐Tf in comparison with ART‐L in the targeting of the HCT‐8 cell line and an improved cytotoxicity as a result of the presence of iron ions, which resulted in concomitant synergism derived from the increased expression of transferrin receptors on the surface of the tumor cells.
phylosignal: an R package to measure, test, and explore the phylogenetic signal
Authors: Keck François , Rimet Frédéric , Bouchez Agnès , Franc Alain 
Published: March 2016

AbstractPhylogenetic signal is the tendency for closely related species to display similar trait values as a consequence of their phylogenetic proximity. Ecologists and evolutionary biologists are becoming increasingly interested in studying the phylogenetic signal and the processes which drive patterns of trait values in the phylogeny. Here, we present a new R package,phylosignalwhich provides a collection of tools to explore the phylogenetic signal for continuous biological traits. These tools are mainly based on the concept of autocorrelation and have been first developed in the field of spatial statistics. To illustrate the use of the package, we analyze the phylogenetic signal in pollution sensitivity for 17 species of diatoms.