bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Dynamics of Cardiovascular Health in the Population of Ivano-Frankivsk Region over the Past Seventeen Years
Authors: Vakaliuk Igor , Kozoviy Ruslan , Fedorov Sergiy 
Published: December 2016

The key to increase the level of life expectancy is good health. To study the indicators of cardiovascular health in the population of the Carpathian region, the analysis of the indicators of cardiovascular disease prevalence over the period 1998-2014 was made. The analysis was conducted based on statistical data of the Regional Information-Analytical Center of Medical Statistics and medical records of the Ivano-Frankivsk Regional Clinical Cardiology Dispensary over the period 1998-2014.To identify the population structure in Ivano-Frankivsk region, the analysis of the main demographic indices over the period 1998-2014 was made. The analysis revealed that in 2007, the total population of the Carpathian region was 1,386,000 people while in 2014, it was 1,379,400 people that was 1.05% and 5.76% lower compared to the total population in 1998 (1,463,600 people). Similar tendency was observed across the whole country. During the studied period, the indicators of the overall prevalence of hypertension (all forms) increased by 2.89 times while the indicators of primary disease incidence increased by 1.89 times. The indicator of the overall prevalence of ischemic heart disease among the adult population of Ivano-Frankivsk region during the studied period increased by 2.11 times ranging from 9780.3 to 20629.1 cases per 100,000 population. It should be noted that since 2012 a reduction in the prevalence of angina pectoris from 6545.7 to 6126.2 cases per 100,000 population (by 1.07 times) was observed. The increase in the incidence of acute myocardial infarction from 81 to 108.2 cases per 100,000 population (by 1.34 times) was detected as well. Cardiovascular diseases are known to be the most urgent problem of modern health care system having no geographical, socioeconomic and sexual preferences. They remain to be the major cause of mortality accounting for about 17,300,000 cases per year.Conclusions. Thus, important factors affecting life expectancy of Ivano-Frankivsk region residents include morbidity and mortality due to cardiovascular diseases which have increased recently.
Influência dos organismos internacionais nas políticas educacionais: só há intervenção quando há consentimento?
Authors: Zanferari Talita 
Published: December 2016

Esta resenha apresenta considerações acerca da obra intitulada “Influência dos organismos internacionais nas políticas educacionais: só há intervenção quando há consentimento" escrita por Silvia Regina Canan em 2016. O livro desenvolve seu percurso em torno da discussão sobre as influências de organismos internacionais na educação brasileira. Para as discussões a autora descreve a trajetória destas influências bem como reflexões sobre a formação docente neste panorama denominado globalização. A obra compreende três capítulos além do prefácio, introdução e considerações finais.
Michael Andrews Farrar: Pioneer Artist and Clergyman
Authors: Grover Rachel 
Published: December 2016

The Reverend M.A. Farrar emigrated to Canada West from Wales in May 1862. Settling with his family in Westwood, Peterborough County, within a week he was plunged into the arduous life of a backwoods clergyman, in charge of the two-point parish of Norwood and Hastings, to which Westwood was soon added. Although traveling over primitive roads in horse-drawn vehicles was a trial to such a townsman, the duties of superintendent of education were quickly added to his load; and he also became a forceful member of two school boards. Under his leadership, the Anglican Church in Hastings was completed, and work on the Church in Westwood (later named St Michael's in his honour) was begun. His love of drawing and painting, long a pastime, became a means of adding slightly to his meagre income. Some of his drawings were made into lithographs by Brown and Bautz of Hamilton and offered for sale; and four others were reproduced in The Canadian Illustrated News in 1871 and 1872. It is for his loving depiction of the houses, ragged streetscapes and the waterways of his adopted country that he is remembered today.
A Relational Approach to Constitutional Interpretation: Shared Legislative and judicial Responsibilities
Authors: Hiebert Janet L. 
Published: December 2016

The Canadian Charter of Rights and Freedoms has fundamentally changed governing principles. This essay suggests that judgements about the Charter be viewed as a shared responsibility that is conceived in relational terms. Two different forms of relationship arise under the Charter and influence the judgements that each set of institutional actors makes. One relationship arises from the fact that Parliament and the judiciary are situated differently, relative to the Charter conflict. Political and judicial judgements about how to reconcile conflicting rights and values are influenced by these different points of reference, by the distinct institutional characteristics that Parliament and the judiciary possess, and by the specific responsibilities that characterize their roles. A second form of relationship is the one between Parliament and the judiciary, which arises from the need to reflect on and react to the other's judgement. Both parliamentary and judicial judgements are influenced by the foreseeable knowledge that their respective interpretations may not be the final word on the reconciliation of rights and values. A relational approach conveys the separate yet interconnected approaches taken to rendering judgement. It assumes that both Parliament and courts have valid insights into how legislative objectives should reflect and respect the Charter's normative values. By conceiving of constitutional judgements as a shared responsibility, this has the potential to broaden the level of scrutiny that may otherwise occur if either Parliament or courts were assumed to have the only valid opinion on the merits of legislative choices from a rights perspective.
And Now For Something Completely Northern: Institutions of Governance in the Territorial North
Authors: White Graham 
Published: December 2016

This essay examines some of the distinctive or unique institutions of governance in the territorial North. The purpose of so doing is two-fold: first, to draw to wider attention the unusual and innovative structures and processes of government operating in the North and second, to demonstrate that alternatives beyond the status quo exist for national and provincial political institutions, provided that they reflect the values and experiences of the societies in which they are embedded. The influence of Aboriginal peoples on political institutions and processes is a prominent theme. In addition, variations between and among the three territories (due in substantial measure to the different positions and approaches of their Aboriginal peoples) are highlighted. Northern institutions are treated not as exotic curiosities, but as responses to particular political needs and social contexts.
Parcours migratoires des parents et rapport des enfants à la politique. La part de l’histoire migratoire familiale dans la socialisation politique des descendants d’immigrés
Authors: Lagier Elsa 
Published: December 2016

Les parcours migratoires des parents impriment très fortement l’histoire familiale et la façon dont elle se transmet entre les générations. Les descendants d’immigrés qui s’approprient cette histoire y puisent des éléments à même de donner du sens à leur propre situation. Ils la mobilisent également, plus ou moins consciemment, dans la construction de leur rapport à la politique. Ce sont ces dynamiques de socialisation politique à partir de l’histoire migratoire familiale qui sont étudiées ici. Pour cela, deux types de parcours migratoires sont décrits et illustrés : les migrations « de départ » et les migrations « d’arrivée ». Ces parcours, la façon dont ils sont mis en récit et les questions qu’ils suscitent pour ceux qui en « héritent », dessinent des logiques spécifiques de socialisation politique.
« Faire famille à distance » chez les natifs des Antilles et de La Réunion
Authors: Beaugendre Carole , Breton Didier , Marie Claude-Valentin 
Published: December 2016

Connaissant une émigration très importante depuis de nombreuses décennies, les populations antillaises et réunionnaises offrent un exemple éclairant de l’impact de ces migrations sur les multiples manières de « faire famille à distance » et des enjeux qui s’y attachent, notamment dans la perspective du vieillissement des populations restées sur place. Tirant profit des données de l’enquête MFV couplées à celles du recensement, cet article analyse la situation vécue depuis les départements d’outre-mer (DOM), ses variations d’un département à l’autre, son évolution et ses ressorts sociodémographiques. Les résultats s’appliquent également à décrire le « faire famille » des natifs des DOM installés en métropole. Les enjeux liés à l’éclatement des familles sont d’autant plus cruciaux que ces départements sont particulièrement sous-dotés en équipements d’accueil de personnes âgées, posant la question d’une prise en charge publique dans un contexte où le recours quasi exclusif aux solidarités privées ne suffira plus à répondre aux besoins.
L’immigration familiale : une obligation d’ « intégration républicaine » . Le cas du Contrat d’accueil et d’intégration
Authors: Hachimi-Alaoui Myriam 
Published: December 2016

Cet article s’intéresse aux politiques publiques d’intégration destinées à inculquer aux familles migrantes les « valeurs de la République ». Après avoir rappelé les grandes étapes de la réglementation de l’immigration familiale, nous montrerons comment celle-ci s’est peu à peu imposée comme un problème public, à la faveur d’un changement d’appréhension des femmes de l’immigration, elles-mêmes perçues comme les principales victimes de la famille « traditionnelle ». Enfin, nous nous intéresserons aux discours publics qui ont accompagné la mise en place du Contrat d’accueil et d’intégration (CAI) et du Contrat d’accueil et d’intégration pour la famille (CAIF) ainsi qu’aux formations civiques qui en constituent l’élément essentiel.
Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice
Authors: Wiehe Kevin , Nicely Nathan I. , Lockwood Bradley , Kuraoka Masayuki , Anasti Kara , Arora Sabrina , Bowman Cindy M. , Stolarchuk Christina , Parks Robert , Lloyd Krissey E. , Xia Shi-Mao , Duffy Ryan , Shen Xiaoying , Kyratsous Christos A. , Macdonald Lynn E. , Murphy Andrew J. , Scearce Richard M. , Moody M. Anthony , Alam S. Munir , Verkoczy Laurent , Tomaras Georgia D. , Kelsoe Garnett , Haynes Barton F. 
Published: December 2016

Abstract
In the RV144 gp120 HIV vaccine trial, decreased transmission risk was correlated with Abs that reacted with a linear epitope at a lysine residue at position 169 (K169) in the HIV-1 envelope (Env) V2 region. The K169 V2 response was restricted to Abs bearing Vλ rearrangements that expressed aspartic acid/glutamic acid in CDR L2. The AE.A244 gp120 in AIDSVAX B/E also bound to the unmutated ancestor of a V2-glycan broadly neutralizing Ab, but this Ab type was not induced in the RV144 trial. In this study, we sought to determine whether immunodominance of the V2 linear epitope could be overcome in the absence of human Vλ rearrangements. We immunized IgH- and Igκ-humanized mice with the AE.A244 gp120 Env. In these mice, the V2 Ab response was focused on a linear epitope that did not include K169. V2 Abs were isolated that used the same human VH gene segment as an RV144 V2 Ab but paired with a mouse λ L chain. Structural characterization of one of these V2 Abs revealed how the linear V2 epitope could be engaged, despite the lack of aspartic acid/glutamic acid encoded in the mouse repertoire. Thus, despite the absence of the human Vλ locus in these humanized mice, the dominance of Vλ pairing with human VH for HIV-1 Env V2 recognition resulted in human VH pairing with mouse λ L chains instead of allowing otherwise subdominant V2-glycan broadly neutralizing Abs to develop.
Recent Trends in Management of Allergic Rhinitis
Authors: Panigrahi Rajalaxmi , Acharya Sudhir K 
Published: December 2016

ABSTRACT
Allergic rhinitis is an inflammatory, immunoglobulin E (IgE)- mediated disease, characterized by nasal congestion, rhinorrhea, and sneezing with or without nasal itching. It can significantly interfere with patient's quality of life. The goals of treatment are to provide the patient with symptomatic relief and improve the quality of life with minimal adverse effects. Prevention has been a large focus in the treatment of allergic rhinitis, but few interventions have proven effective. Although dust mite allergies are more common.

How to cite this article
Panigrahi R, Acharya SK. Recent Trends in Management of Allergic Rhinitis. Clin Rhinol An Int J 2016;9(3):130-136.
Concha Bullosa in Paradoxical Middle Turbinate: A New Variation
Authors: El-Anwar Mohammad W , Ali Ahmed I 
Published: December 2016

ABSTRACT

Introduction
Concha bullosa is the most common anatomic variation of osteomeatal complex region that is generally seen in the middle turbinate (MT).

Materials and methods
A 25-year-old male presented with headache and nasal obstruction. Computed tomography (CT) scan documented right paradoxical MT. The right MT also showed aerated concha bullosa with narrow right osteomeatal area. Routine preoperative laboratory tests were within normal limits.

Results
This case of concha bullosa in paradoxically bent MT was reported, described, and could be safely managed endoscopically. Patient was symptom free up to date without any complication, recurrence, or other pathology.

Conclusion
Computed tomography may easily identify such uncommon anatomic variations of the osteomeatal region. This directs the surgeon attention to these variations as a cause of headache and osteomeatal area obstruction.

How to cite this article
El-Anwar MW, Ali AI. Concha Bullosa in Paradoxical Middle Turbinate: A New Variation. Clin Rhinol An Int J 2016;9(3):141-142.
A Rare Case of Pediatric Self-inflicted Meningoencephalocele
Authors: Rajasekar MK , Sankar Malarvizhi R 
Published: December 2016

ABSTRACT
Cerebrospinal fluid (CSF) rhinorrhea is common in traumatic penetrating nasal injuries. In the pediatric age group, we often encounter self-inflicted foreign body injuries of blunt type, which rarely leads to any complications. We came across a case of CSF rhinorrhea due to self-inflicted penetrating nasal injury, after 7 years of initial injury. In this case, the sharp end of a screw nail had injured the fovea ethmoidalis and caused a meningoencephalocele on removal, which had been asymptomatic until 4 years ago, when the patient came with CSF rhinorrhea. Miraculously, there were no complications in the period before presentation and after surgical correction.

How to cite this article
Rajasekar MK, Sankar MR. A Rare Case of Pediatric Self-inflicted Meningoencephalocele. Clin Rhinol An Int J 2016;9(3):143-145.
Bilateral Complete Congenital Choanal Atresia in an 18-month-old Female Child with Rare Clinical Presentation: Transnasal Endoscopic Repair with Stent
Authors: Mohindra Satyawati 
Published: December 2016

ABSTRACT
Congenital choanal atresia (CCA) is the developmental failure of the nasal cavity to communicate with the nasopharynx. Surgical repair is recommended in the first weeks of life in bilateral congenital choanal atresia (BCCA), because this is a life-threatening situation in newborns as they are obligate nose breathers. This article reports on an 18-month-old female child, with delayed presentation of bilateral choanal atresia, treated successfully endoscopically and stent placement postoperatively.

Case report
The patient is an 18-month-old female child, born full term, by cesarean section (for cephalopelvic disproportion) with birth weight 3,750 gm to a 30-year-old primigravida. There were no immediate prenatal or postnatal medical or surgical problems in the mother. The child cried immediately after birth, there was no postnatal respiratory distress, cyanosis, or any major hospital admission. On examination, microcephaly (head circumference 46 cm below 2 standard deviation of the mean), hypertelorism, ani-Mongolian slanted eyes, left side cleft lip with high arched palate with malocclusion were observed. She presented late with c/o nasal discharge and mild breathing difficulty on breastfeeding. The catheter test revealed the diagnosis of BCCA. Noncontrast computed tomography (CT) scan nose was done, which showed nonposterior choana blocked with bony plates on both the sides (Fig. 1). The paranasal sinuses, orbit, and anterior nasal cavities were within normal limits. Transnasal endoscopic repair was done under general anesthesia. Endoscopy revealed a bony atresia (Fig. 2), which was drilled out keeping the direction medially and inferiorly. Feeding tubes were fashioned as stents and placed for a period of 6 weeks. There were no postoperative complications. The patient was referred to pediatric surgery for other problems. Endoscopy confirmed bilateral patency at 12 weeks postoperatively.

How to cite this article
Mohindra S, Gupta AK. Bilateral Complete Congenital Choanal Atresia in an 18-month-old Female Child with Rare Clinical Presentation: Transnasal Endoscopic Repair with Stent. Clin Rhinol An Int J 2016;9(3):153-154.
Ovarian Yolk Sac Tumor: A Case Report with Review Of Literature
Authors: Sreehari A , Rupakala BM 
Published: December 2016

ABSTRACTA total of 3 to 5% of all ovarian malignancies include malignant ovarian germ cell tumors (MOGCTs). They are subdivided into germinomatous and non-germinomatous tumors. Common types of non-germinomatous tumors include yolk sac and immature teratoma. Ovarian yolk sac tumors (YST) are the second most frequent histological subtype of MOGCTs, after ovarian dysgerminoma. They account for 20% of MOGCTs and are frequent especially in childhood and in early adulthood. We report the case of a yolk sac tumor of the ovary in a 13yrs years old female.How to cite this articleSreehari A, Rupakala BM, Sarojamma C. Ovarian Yolk Sac Tumor: A Case Report with Review of Literature. J Med Sci 2016;2(1):15-17.
Bilateral Femoral Neck Fracture due to Electric Shock
Authors: Peswani Rahul , Chandrakar BL , Thakkar Rakesh 
Published: December 2016

ABSTRACTSimultaneous bilateral fractures of the femoral neck are rare injuries in patients without underlying pathological conditions. We report a case of a 50-year-old male, who sustained bilateral femoral neck injury resulting from electric shock with 440 V of direct current. Bilateral femoral neck fracture is rare. Bilateral femoral neck fracture due to electric shock is even rarer. This case report highlights bilateral femoral neck fracture without primary and secondary bone disease. Late presentation and unclassified pattern of fracture are the other features.How to cite this articlePeswani R, Chandrakar BL, Thakkar R. Bilateral Femoral Neck Fracture due to Electric Shock. J Med Sci 2016;2(1):18-20.
Increased healthcare use up to 10 years among relapse‐free Hodgkin lymphoma survivors in the era of intensified chemotherapy and limited radiotherapy
Authors: Glimelius Ingrid , Eloranta Sandra , Ekberg Sara , Chang Ellen T. , Neovius Martin , Smedby Karin E. 
Published: December 2016

AbstractWith today's excellent cure rates for Hodgkin lymphoma (HL), the number of long‐term survivors is increasing. This study aims to provide a global assessment of late adverse effects for working‐age HL survivors treated with contemporary protocols (combination chemotherapy and limited radiotherapy). From Swedish nationwide registers we identified 1017 HL survivors diagnosed in 2000–2009, aged 18–60 years (median 32) and surviving at least one year post‐diagnosis, and 4031 age‐, sex‐, and calendar‐year‐matched population comparators. Incidence rate ratios (IRR) and 95% confidence intervals (95%CI) for outpatient visits and inpatient bed‐days after the first year up to 14 years post‐diagnosis (through 2013) were estimated across treatment subgroups, considering relapse‐free time and using negative binomial regression. Scheduled outpatient visits for HL were excluded. The rate of outpatient visits was nearly double (IRR = 1.8, 95%CI: 1.6–2.0) that among comparators and higher rates persisted up to 10 years post‐diagnosis. The rate of inpatient bed‐days among relapse‐free survivors was more than three‐fold (IRR = 3.6, 95%CI: 2.7–4.7) that of comparators and the increase persisted up to four years post‐diagnosis. Patients requiring 6‐8 chemotherapy courses had higher rates of outpatient visits (IRR = 1.4, 95%CI: 1.1–1.7) and bed‐days (IRR = 4.7, 95%CI: 2.9–7.8) than patients treated with 2–4 courses + radiotherapy. Previously seldom reported reasons for the excess healthcare use included chest pain, keratitis, asthma, diabetes mellitus, and depression. Contemporary treatment, chemotherapy in particular, was associated with excess healthcare use among HL survivors during the first decade postdiagnosis. The reasons for healthcare visits reflected a wide range of disorders, indicating the need of broad individualized care in addition to specific screening programs.
Bone marrow cellularity at day 14 is the most important predictive factor for response in patients with AML who require double‐induction chemotherapy: Analysis from a large, single institution experience
Authors: Griffin Patrick T. , Komrokji Rami S. , Sweet Kendra , Al Ali Najla H. , Padron Eric , Kubal Timothy E. , List Alan F. , Lancet Jeffrey E. 
Published: December 2016

AbstractIn patients with acute myeloid leukemia (AML), the presence of residual disease at day 14 after primary induction therapy warrants consideration of a second induction cycle. However, data to guide retreatment decisions in such patients are presently limited. Here, we retrospectively reviewed data from 176 patients with AML treated at our institution with a second induction chemotherapy regimen because of day 14 residual disease. Clinical variables and nadir bone marrow features were assessed for correlations with complete remission (CR) and overall survival (OS). In our patient group, 59% achieved CR after a second induction course. Median OS for the entire group was 12.40 months (95% CI, 9.90‐14.90) but 19.07 months (95% CI, 13.13‐25.01) for those who attained a CR. Nadir marrow hypocellularity (P < 0.001) at day 14, absolute blast reduction of >50% (P = 0.030), and de novo disease status (P = 0.018) were significantly correlated with CR achievement after re‐induction. Marrow hypocellularity at day 14 was the most significant predictor of CR on multivariate analysis (P < 0.001). Nadir marrow features did not independently correlate with OS when accounting for CR status. Re‐induction was successful in achieving CR in most patients. Study patients who did not achieve CR were more likely to have nonhypocellular marrows.