bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of internal and external market orientation on the performance of non-conventional Islamic financial institutions
Authors: Zebal Mostaque Ahmed 
Published: December 2017

Purpose
The purpose of this study was to explore the impact of internal and external market orientations on monetary and non-monetary performances of non-conventional Islamic financial institutions. This study further aimed at proposing a conceptual framework, testing it and examining relationships among the variables.

Design/methodology/approach
Data for this study were collected from 132 branches of 11 non-conventional financial institutions in Bangladesh using a closed-ended questionnaire. The study considered a structural equation modeling approach for testing the proposed model. A two-step procedure was used for this purpose. First, a measurement model was analyzed through a confirmatory factor analysis; second, the structured model was evaluated to examine relationships between the constructs. Data used in this study confirmed the adequate reliability, convergent and discriminant validity.

Findings
The results of the study met the expectations and provided an evidence that both monetary and non-monetary business performances are functions of internal and external market orientations’ efforts. As the results are reported, all three components of internal market orientation, e.g. internal intelligence generation, dissemination and responsiveness, were found to be statistically significant and positively related to monetary and non-monetary performances, except internal intelligence responsiveness with employees’ team spirits. The study also revealed a significant relationship between all three external market orientation components, and business performance, except external intelligence responsiveness, was not found to have a significant relationship with team spirit and customer retention. The results, however, imply that the performance of non-conventional financial institutions is an integrated effort of both internal and external orientations rather than using a single approach.

Originality/value
Findings of this study support the theoretical arguments that non-conventional financial institutions can be successful in attaining all types of performances by initiating and adopting internal and external market-oriented activities. The study further argues the importance of the activities under each market orientation component and suggests non-conventional financial institutions to promote such an initiative if they are to be consistent in their performances.
Review article: Methodology for the ‘rapid review’ series on musculoskeletal injuries in the emergency department
Authors: Strudwick Kirsten , McPhee Megan , Bell Anthony , Martin‐Khan Melinda , Russell Trevor 
Published: December 2017

AbstractMusculoskeletal injuries are a common presentation to the ED, with significant costs involved in the management of these injuries, variances in care within the ED and associated morbidity. A series of rapid review papers were completed to guide best practice for the assessment and management of common musculoskeletal injuries presenting to the ED. This paper presents the methodology used across the rapid reviews. PubMed, CINAHL, EMBASE, TRIP and the grey literature, including relevant organisational websites, were searched in 2015. The search was repeated consistently for each topic area (injuries of the foot and ankle, knee, hand and wrist, elbow, shoulder, lumbar spine and cervical spine). English‐language primary studies, systematic reviews and guidelines that were published in the last 10 years and addressed acute musculoskeletal injury management were considered for inclusion. Data extraction of each included article was conducted, followed by a quality appraisal. The extracted data from each article was synthesised to group similar evidence together. For each rapid review, the evidence has been organised in a way that a clinician can direct their attention to a specific component of the clinical cycle of care in the ED, such as the assessment, diagnostic tests, management and follow‐up considerations from ED. The series of rapid reviews are designed to foster evidence‐based practice within the ED, targeting the injuries most commonly presenting. The reviews provide clinicians in EDs with rapid access to the best current evidence, which has been synthesised and organised to assist decision‐making.
Major haemorrhage fatalities in the Australian national coronial database
Authors: Gipson Jacob S , Wood Erica M , Cole‐Sinclair Merrole F , McQuilten Zoe , Waters Neil , Woodford Noel W 
Published: December 2017

AbstractObjectiveThe aim of the study is to describe the epidemiology of major bleeding fatalities.MethodsA case series analysis of Australia's National Coronial Information System was conducted. Keywords were used to search for closed cases of major haemorrhage in the state of Victoria for the period 1 January 2009 to 31 December 2011. Coroners’ findings, autopsy reports and police reports of cases were reviewed. Demographic data were extracted, and cases were assigned to a clinical bleeding context.ResultsA total of 427 cases of major bleeding causing death were identified. The cohort was predominately men (69%), with a median age of 63 years (interquartile range 45–77 years). Trauma accounted for 38%, gastrointestinal haemorrhage 28%, surgical/procedural bleeding 14%, ruptured/leaking aneurysms 12% and other 8%. Most events began in homes (46%), hospitals (22%) and at the roadside (17%). Of those whose haemorrhage began in the community, 69% did not survive to hospital.ConclusionsMajor bleeding fatalities occurred across a diverse range of contexts, with trauma and gastrointestinal bleeding accounting for most deaths. The majority of patients did not survive to reach hospital. Major haemorrhage occurring entirely outside hospital may be underrecognised from analyses of datasets based primarily on traumatic or in‐hospital bleeding. These findings have implications for management of pre‐hospital resuscitation and development of clinical practice guidelines for identification and management of major bleeding in the community.
Homelessness and Emergency Medicine: A Review of the Literature
Authors: Salhi Bisan A. , White Melissa H. , Pitts Stephen R. , Wright David W. 
Published: December 2017

AbstractObjectivesWe aimed to synthesize the available evidence on the demographics, prevalence, clinical characteristics, and evidence‐based management of homeless persons in the emergency department (ED). Where appropriate, we highlight knowledge gaps and suggest directions for future research.MethodsWe conducted a systematic literature search following databases: PubMed, Ovid, and Google Scholar for articles published between January 1, 1990, and December 31, 2016. We supplemented this search by cross‐referencing bibliographies of the retrieved publications. Peer‐reviewed studies written in English and conducted in the United States that examined homelessness within the ED setting were included. We used a qualitative approach to synthesize the existing literature.ResultsTwenty‐eight studies were identified that met the inclusion criteria. Based on our study objectives and the available literature, we grouped articles examining homeless populations in the ED into four broad categories: 1) prevalence and sociodemographic characteristics of homeless ED visits, 2) ED utilization by homeless adults, 3) clinical characteristics of homeless ED visits, and 4) medical education and evidence‐based management of homeless ED patients.ConclusionHomelessness may be underrecognized in the ED setting. Homeless ED patients have distinct care needs and patterns of ED utilization that are unmet by the current disease‐oriented and episodic models of emergency medicine. More research is needed to determine the prevalence and characteristics of homelessness in the ED and to develop evidence‐based treatment strategies in caring for this vulnerable population.
Personalized stepwise vascular control during complex hepatectomy involving hepatocaval confluence
Authors: Dou Lei , Yu Zong‐ping , Yang Hui‐yuan , Ran Ji , Chen Yi‐Fa , Chen Xiao‐Ping 
Published: December 2017

BackgroundThis study introduces an innovative stepwise vascular control technique to address the high risk of massive bleeding from main hepatic veins and the retro‐hepatic inferior vena cava during hepatectomy involving hepatocaval confluence.MethodsFrom January 2010 to July 2016, 80 patients underwent stepwise vascular occlusion during complex liver resection involving hepatocaval confluence. Relevant clinical data were collected and compared with those obtained in parallel studies. The protocol has been registered in the Protocol Registration and Results System as protocol NCT02996006.ResultsAll 80 patients underwent portal triad (PT), infra‐hepatic inferior vena cava (IIVC) and supra‐hepatic inferior vena cava (SIVC) preparation for occlusion in that order; PT, PT + SIVC and PT + IIVC + SIVC occlusions were performed during liver resection for six, 42 and 32 patients, respectively. The PT, IIVC and SIVC clamping times were 12.9 ± 2.5, 9.1 ± 2.1 and 5.1 ± 1.4 min, respectively. The mean blood loss was 504.1 ± 234.5 mL. Sixteen patients received blood transfusions. Haemodynamic parameters remained stable. No patients had life‐threatening complications or died (Clavien‐Dindo grade IV or V). Compared with other techniques used in parallel studies, this technique has the advantage of decreased blood loss in less warm ischaemia time.ConclusionFor complex hepatectomy involving hepatocaval confluence, this newly described stepwise vascular control technique was efficacious and feasible for controlling intraoperative bleeding.
Long‐term cardiovascular reprogramming by short‐term perinatal exposure to nicotine's main metabolite cotinine
Authors: Bastianini Stefano , Lo Martire Viviana , Silvani Alessandro , Zoccoli Giovanna , Berteotti Chiara , Lagercrantz Hugo , Arner Anders , Cohen Gary 
Published: December 2017

AbstractAimGather ‘proof‐of‐concept’ evidence of the adverse developmental potential of cotinine (a seemingly benign biomarker of recent nicotine/tobacco smoke exposure).MethodsPregnant C57 mice drank nicotine‐ or cotinine‐laced water for 6 wks from conception (NPRE = 2% saccharin + 100 μg nicotine/mL; CPRE = 2% saccharin + 10 μg cotinine/mL) or 3 wks after birth (CPOST = 2% saccharin + 30 μg cotinine/mL). Controls drank 2% saccharin (CTRL). At 17 ± 1 weeks (male pups; CTRL n = 6; CPOST n = 6; CPRE n = 8; NPRE n = 9), we assessed (i) cardiovascular control during sleep; (ii) arterial reactivity ex vivo; and (iii) expression of genes involved in arterial constriction/dilation.ResultsBlood cotinine levels recapitulated those of passive smoker mothers’ infants. Pups exposed to cotinine exhibited (i) mild bradycardia – hypotension at rest (p < 0.001); (ii) attenuated (CPRE, p < 0.0001) or reverse (CPOST; p < 0.0001) BP stress reactivity; (iii) adrenergic hypocontractility (p < 0.0003), low protein kinase C (p < 0.001) and elevated adrenergic receptor mRNA (p < 0.05; all drug‐treated arteries); and (iv) endothelial dysfunction (NPRE only).ConclusionCotinine has subtle, enduring developmental consequences. Some cardiovascular effects of nicotine can plausibly arise via conversion into cotinine. Low‐level exposure to this metabolite may pose unrecognised perinatal risks. Adults must avoid inadvertently exposing a foetus or infant to cotinine as well as nicotine.
Cortisol and blood pressure levels decreased in fathers during the first hour of skin‐to‐skin contact with their premature babies
Authors: Varela Natalia , Tessier Réjean , Tarabulsy George , Pierce Tamarha 
Published: December 2017

AbstractAimPremature birth is an extremely stressful experience. In 2013 to 2014, we explored the physiological stress responses of fathers during their first skin‐to‐skin contact (SSC) with their new baby.MethodsWe recruited 49 fathers whose partners had given birth to a premature baby of up to 33 weeks and three days. The study, in the neonatal intensive care unit (NICU) of a Quebec hospital, measured the physiological stress responses of the fathers before and after they first experienced SSC with their new baby. Cortisol levels and blood pressure were measured, and a generalised estimating equation was used for the data analysis.ResultsThe fathers’ cortisol levels decreased from 10.55 nmol/L, with a 95% confidence interval (95% CI) of 9.61–11.59 at the beginning of the experiment to 8.26 nmol/L (95% CI: 7.51–9.07) after 75 minutes. Meanwhile, their systolic blood pressure decreased from 135.16 mmHg (95% CI: 130–140) to 125.25 mmHg (95% CI: 121–129).ConclusionFathers who held their baby in SSC for the first time showed a significant reduction in physiological stress responses. Our findings support hospital practices that enable fathers to experience their first intimate contact with their newborn infant in the NICU.
Closure of the cystic duct orifice in laparoscopic subtotal cholecystectomy for severe cholecystitis
Authors: Matsumura Tatsuki , Komatsu Shunichiro , Komaya Kenichi , Ando Keiichi , Arikawa Takashi , Ishiguro Seiji , Saito Takuya , Osawa Takaaki , Kurahashi Shintaro , Uchino Tairin , Yasui Kohei , Kato Shoko , Suzuki Kenta , Kato Yoko , Sano Tsuyoshi 
Published: December 2017

AbstractIntroductionLaparoscopic subtotal cholecystectomy (LSC) has been recognized as an alternative to conversion to laparotomy for severe cholecystitis. However, it may be associated with an increased risk of recurrent stones in the gallbladder remnant. The objective of this study was to evaluate the safety and feasibility of the complete removal of the gallbladder cavity in LSC for severe cholecystitis using the cystic duct orifice suturing (CDOS) technique.MethodsIn a consecutive series of 412 laparoscopic cholecystectomies that were performed from January 2015 to June 2017, 12 patients who underwent LSC with CDOS were enrolled in this retrospective study. In this procedure, Hartmann's pouch was carefully identified, and the infundibulum–cystic duct junction was transected while the posterior wall adherent to Calot's triangle was left behind. The clinical records, including the operative records and outcomes, were analyzed.ResultsThe median operating time and blood loss were 158 min and 20 mL, respectively. In all cases, LSC with CDOS was completed without conversion to open surgery. No injuries to the bile duct or vessels were experienced. The median postoperative hospital stay was 6 days. Postoperative complications occurred in two patients (bile leakage, n = 1: common bile duct stones, n = 1) and were successfully treated by endoscopic management. A gallbladder remnant was not delineated by postoperative imaging in any of the cases.ConclusionThese results suggest that LSC with CDOS is a promising approach that can avoid dissection of Calot's triangle and achieve the complete removal of the gallbladder cavity in patients with severe cholecystitis.
Newcastle disease virus co‐expressing interleukin 7 and interleukin 15 modified tumor cells as a vaccine for cancer immunotherapy
Authors: Xu Xiaojing , Sun Qing , Mei Yu , Liu Yonghao , Zhao Lixiang 
Published: December 2017

Interleukin 15 (IL15) and IL7 are two cytokines essential for T cell development and homeostasis. In order to improve the antitumor activity by Newcastle disease virus (NDV)‐modified tumor vaccine, we generated a recombinant NDV co‐expressing IL15 and IL7 (LX/IL(15+7)) through incorporation of a 2A self‐processing peptide into IL15 and IL7 using reverse genetics. B16 cells infected with LX/IL(15+7) expressed both IL15 and IL7 stably. The cytotoxicity assay showed that murine melanoma cells modified with LX/IL(15+7) could significantly enhance the antitumor immune response in vitro. Then, the antitumor effects of tumor vaccine modified with recombinant virus were tested in the murine tumor models. We observed strong antitumor responses induced by LX/IL(15+7)‐modified tumor cells both in prophylaxis and therapeutic models. Although the tumor‐infiltrating CD4+ T cells and CD8+ T cells were both increased, the antitumor activity of the tumor vaccine modified with LX/IL(15+7) was dependent on CD8+ T cells. Taken together, our data strongly indicated that tumor vaccine modified with NDV strain LX/IL(15+7) is a promising agent for cancer immunotherapy.
Are Trees Rooting for Us? The Heritage of Greening in Qatar
Authors: Rico Trinidad 
Published: December 2017

AbstractThis article considers the emergence and role of “heritage trees” in Qatar. I suggest these trees are emblematic of a cultural heritage discourse that constructs a specific relationship to the landscape, one that is simultaneously informed by an imagined past and a desired future. I contextualize this development within the phenomenon of “survivor trees,” a global discourse that mobilizes a heritage rhetoric about anxieties of loss and desires for adaptation, in order to account for the recent appearance of “heritage trees” in Qatar as part of its efforts to build and mobilize its citizens’ support for a sustainable future. This discussion highlights the ways in which heritage discourses may be mobilized as powerful technologies in the construction of environmental imaginaries.
After Wheat: Revitalizing Sicilian Agriculture through Heritage Tourism
Authors: Samuels Joshua 
Published: December 2017

AbstractSicily was once the breadbasket of the Roman Empire, but by the 20th century Sicilian wheat production had declined dramatically due to deforestation and changing economic, political, and climactic conditions. Alternatives to wheat production are now being actively promoted in order to revitalize Sicily's rural economy. These include the Via dei Borghi, an ambitious project proposed by Sicily's Agency for Agricultural Development (ESA) to promote “slow tourism” through the island's interior using the appeal of traditional agricultural heritage. The borghi at the heart of the project are rural centers associated with the Fascist “Battle for Wheat” that were designed to hobble the traditional agricultural systems that ESA is valorizing. The result is an ironic but creative requalification of the borghi that incentivizes farmers to focus on diverse and unique local products, providing one answer to the question of what to produce after wheat.
You Can't Grow Potatoes in the Sky: Building Resilience in the Face of Climate Change in the Potato Park of Cuzco, Peru
Authors: Sayre Matthew , Stenner Tammy , Argumedo Alejandro 
Published: December 2017

AbstractAlthough Quechua farmers contribute little to climate change, they are disproportionately experiencing the impacts of rapid changes in the high‐altitude environment of the Andes. We describe how Quechua farmers and Association ANDES, a local non‐profit organization, are rising to the challenge in Peru, using traditional knowledge and science in community‐led research to mitigate and adapt to the impacts of climate change. A globally important food crop, the potato (Solanum sp.) originated in the central Andean Mountains. Indigenous farmers collectively manage the Potato Park as a Biocultural Heritage Territory, and together with ANDES, are implementing the Pluriversity for Biocultural Landscapes and Resilient Food Systems to facilitate knowledge exchange and creative solution seeking for complex global problems such as climate change. We describe programs that support community resilience, local biocultural heritage, biocultural products and services, and global policy processes strengthening the rights of Pacha Mama (Mother Earth) and world indigenous peoples.
An observational study of benzodiazepine prescription during inpatient alcohol detoxification for patients with vs. without chronic pretreatment with high‐dosage baclofen
Authors: Martinez Laura , Vorspan Florence , Declèves Xavier , Azuar Julien , Fortias Maeva , Questel Franck , Dereux Alexandra , Grichy Leslie , Barreteau Hélène , Bellivier Frank , Lépine Jean‐Pierre , Bloch Vanessa 
Published: December 2017

AbstractHigh‐dose baclofen is prescribed as a maintenance treatment to reduce alcohol use in patients with alcohol use disorder. Nevertheless, some patients still have massive alcohol intakes and require inpatient alcohol withdrawal. To compare the oral dose of benzodiazepine prescribed to manage alcohol withdrawal symptoms in patients with vs. without steady‐state pretreatment with high‐dose baclofen. Retrospective chart review study. Prescribed benzodiazepine dose expressed in diazepam‐equivalent was compared between groups. Thirty‐one patients were assessed in the high‐dose maintenance baclofen group and compared to 31 matched patients not receiving baclofen. No statistically significant difference was evident between groups regarding levels of benzodiazepines prescribed. The mean diazepam‐equivalent dose during the first 7 days was 294 ± 149 mg in the baclofen group vs. 310 ± 133 mg (t‐test = 0.440, P = 0.661) in matched controls. Steady‐state high‐dose baclofen before an inpatient alcohol cessation hospitalization does not lower the needed benzodiazepine dose in the management of alcohol withdrawal symptoms.
Efficacy and safety of fesoterodine treatment for overactive bladder symptoms in elderly women with and without hypertension
Authors: Yokoyama Osamu , Yamagami Hidetomi , Hiro Shintaro , Hotta Shinichi , Yoshida Masaki 
Published: December 2017

ObjectiveTo assess fesoterodine treatment in elderly women with overactive bladder with and without hypertension.MethodsData for 2527 elderly women with overactive bladder symptoms, including urgency urinary incontinence, were pooled from 10 double‐blind, placebo‐controlled fesoterodine studies.ResultsA total of 1523 elderly women (60.3%) had a history of hypertension, and 1004 women (39.7%) had no hypertension history. Overactive bladder symptoms, mean bodyweight and mean body mass index at baseline were significantly higher in women with overactive bladder and hypertension versus those without hypertension (P < 0.05). Statistically significant improvements in overactive bladder symptoms at week 12 were observed for fesoterodine treatment versus placebo in women with hypertension and those without (P < 0.05). The diary‐dry rate (no urgency urinary incontinence episodes), the proportion with less than eight micturitions/24 h, overactive bladder symptom bother and health‐related quality of life were also statistically significantly improved by fesoterodine treatment in both populations. Incidence of treatment‐related adverse events with fesoterodine was similar in women with hypertension (39.3%) and without hypertension (44.6%). Dry mouth and constipation were the most common treatment‐related adverse events with fesoterodine in women with hypertension (26.2% and 5.2%, respectively) and without hypertension (30.5% and 8.0%).ConclusionsA relationship among the severity of overactive bladder symptoms, hypertension and obesity in elderly women is suggested. Fesoterodine provides significantly greater improvements in overactive bladder symptoms and health‐related quality of life versus placebo in women with or without hypertension. Hypertension does not appear to affect the efficacy and safety of fesoterodine in elderly women with overactive bladder symptoms, including urgency urinary incontinence.