bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parent and Child Trauma Symptoms During Child–Parent Psychotherapy: A Prospective Cohort Study of Dyadic Change
Authors: Hagan Melissa J. , Browne Dillon T. , Sulik Michael , Ippen Chandra Ghosh , Bush Nicole , Lieberman Alicia F. 
Published: November 2017

AbstractFive randomized controlled trials have shown that child–parent psychotherapy (CPP) improves trauma symptoms in children. Less is known about parent symptoms or moderators of symptom change. In a sample of 199 parent (81% biological mother; 54% Latina/o) and child (aged 2 to 6 years; 52% male; 49% Latina/o) dyads who participated in an open treatment study of CPP, this study investigated whether parent and child symptoms similarly decreased during treatment and whether improvement was moderated by parent, child, and treatment characteristics. Parents completed baseline and posttreatment interviews regarding exposure to traumatic events, posttraumatic stress symptomatology (PTSS), and other mental health indices. Latent difference score analysis showed that PTSS significantly decreased by more than 0.5 SD for parents and children. The PTSS improvement in parents was associated with reductions in child avoidance, r = .19, p = .040, and hyperarousal, r = .33, p < .001. Girls showed a greater reduction than boys in reexperiencing, β = −.13, p = .018, and hyperarousal, β = −.20, p = .001. Contrary to expectations, parent and child improvement in PTSS was greater for those with fewer parental lifetime stressors, βrange = .15 to .33, and for those who participated in fewer treatment sessions, βrange = .15 to .21. The extent of improvement in parent PTSS varied based on clinician expertise, β = −.20, p = .009. Significant reductions in parent and child PTSS were observed during community‐based treatment, with CPP and symptom improvement varying according to child, parent, and treatment characteristics.
Successful and safe use of Q‐switched lasers in the treatment of nevus of Ota in children with phototypes IV–VI
Authors: Belkin Daniel A. , Jeon Hana , Weiss Elliot , Brauer Jeremy A. , Geronemus Roy G. 
Published: November 2017

ObjectiveNevus of Ota represents congenital dermal melanocytosis in a trigeminal distribution, most commonly occurring in Asian individuals and other individuals with skin of color. Evidence suggests early treatment is beneficial. Multiple reports have shown efficacy and safety of Q‐switched laser treatment in adults. There is little data on children and in non‐Asian skin types. This series was done to demonstrate safe and effective use of Q‐switched laser therapy in children of multiple skin types.Study DesignRetrospective case series.MethodsThis was a chart review of patients under 18 years old who presented to our practice from 2002 to 2015 with a clinical diagnosis of nevus of Ota who were treated with Q‐switched lasers (694 and 1,064 nm). Patients were treated without the use of general anesthesia or sedation, and corneal shields were used in appropriate cases. Percentage of improvement as well as side effects were rated by five physicians independently. Improvement, when present, was rated in quartiles (1–25%, 26–50%, 51–75%, and 76–100% improvement).ResultsTwenty‐four children were included. The average age at the start of treatment was 3.9 years old (range of 3 months to 12.4 years), and patients had Fitzpatrick skin types IV through VI. The mean number of treatments was 9.3. Assessment revealed excellent response (76–100% improvement) in 70% of patients and good to excellent response (51–100% improvement) in 86%. Two patients (8%) had post‐inflammatory hyperpigmentation, one of whom also had focal hypopigmentation.ConclusionTreatment of nevus of Ota with Q‐switched lasers in children with skin of color, without general anesthesia or sedation, is safe and effective. Early intervention should be encouraged for better efficacy and to prevent psychosocial distress in later childhood and adulthood. Lasers Surg. Med. 50:56–60, 2018. © 2017 Wiley Periodicals, Inc.
Automatic renal lesion segmentation in ultrasound images based on saliency features, improved LBP, and an edge indicator under level set framework
Authors: Gui Luying , Yang Xiaoping 
Published: November 2017

PurposeSegmentation of lesions in ultrasound images is widely used for preliminary diagnosis. In this paper, we develop an automatic segmentation algorithm for multiple types of lesions in ultrasound images. The proposed method is able to detect and segment lesions automatically as well as generate accurate segmentation results for lesion regions.MethodsIn the detection step, two saliency detection frameworks which adopt global image information are designed to capture the differences between normal and abnormal organs as well as these between lesions and the normal tissues around them. In the segmentation step, three types of local information, i.e., image intensity, improved local binary patterns (LBP) features, and an edge indicator, are embedded into a modified level set framework to carry out the segmentation task.ResultsThe cyst and carcinoma regions in the ultrasound images of the human kidneys can be automatically detected and segmented by using the proposed method. The efficiency and accuracy of the method are validated by quantitative evaluations and comparative measurements with three well‐recognized segmentation methods. Specifically, the average precision and dice coefficient of the proposed method in segmenting renal cysts are 95.33% and 90.16%, respectively, while those in segmenting renal carcinomas are 94.22% and 91.13%, respectively. The average precision and dice coefficient of the proposed method are higher than those of three compared segmentation methods.ConclusionsThe proposed method can efficiently detect and segment the renal lesions in ultrasound images. In addition, since the proposed method utilizes the differences between normal and abnormal organs as well as these between lesions and the normal tissues around them, it can be possibly extended to deal with lesions in other organs of ultrasound images as well as lesions in medical images of other modalities.
Strong winds in a coupled wave–atmosphere model during a North Atlantic storm event: evaluation against observations
Authors: Pineau‐Guillou Lucia , Ardhuin Fabrice , Bouin Marie‐Noëlle , Redelsperger Jean‐Luc , Chapron Bertrand , Bidlot Jean‐Raymond , Quilfen Yves 
Published: November 2017

Strong winds may be biased in atmospheric models. Here the European Centre for Medium‐range Weather Forecasts (ECMWF) coupled wave–atmosphere model is used (i) to evaluate strong winds against observations, and (ii) to test how alternative wind stress parametrizations could lead to a more accurate model. For the period of storms Kaat and Lilli (23–27 January 2014), we compared simulated winds with in situ – moored buoys and platforms – and satellite observations available from the North Atlantic. Five wind stress parametrizations were evaluated. The first result is that moderate simulated winds (5–20 m s−1) match with all observations. However, for strong winds (above 20 m s−1), mean differences appear, as much as −7 m s−1 at 30 m s−1. Significant differences also exist between observations, with buoys and Advanced Scatterometer ASCAT‐KNMI generally showing lower wind speeds than the platforms and other remote‐sensing data used in this study (AMSR2, ASCAT‐RSS, WindSat, SMOS and JASON‐2). Buoy and ASCAT‐KNMI winds are likely to underestimate the real wind speed. It is difficult to conclude which dataset should be used as a reference. The second result is that common wave‐age dependent parametrizations produce unrealistic drags and are not appropriate for coupling, whereas a newly empirically adjusted Charnock parametrization leads to higher winds compared to the default ECMWF parametrization. This proposed new parametrization may lead to more accurate results in an operational context.
Facile Preparation of Cu‐Al Oxide Catalysts and Their Application in the Direct Synthesis of Ethanol from Syngas
Authors: Li Xiaoli , Zhang Qingde , Xie Hongjuan , Gao Xiaofeng , Wu Yingquan , Yang Guohui , Wang Peng , Tian Shaopeng , Tan Yisheng 
Published: November 2017

AbstractA simplified catalytic system K‐Cu/Al2O3 (KCA‐xCu‐T) with Cu‐Al oxides was prepared by a facile impregnation method and was successfully applied in the direct synthesis of ethanol from syngas. The results demonstrated that the distribution of CuO, CuAl2O4, and CuAlO2 in KCA‐xCu‐T catalysts can be effectively tuned by varying the calcination temperature (T/°C) and CuO loading (xCu/wt%). The cooperative effect between Cu0 and CuAlO2(Cu+) was proved to be responsible for the enhanced ethanol selectivity. Furthermore, the formation of CuAlO2 could efficiently fix Cu+ species in KCA‐10Cu‐900 sample, and thus lead to excellent catalytic stability (300 h at 400 °C). CuAl2O4 itself has no catalytic effect but can be gradually decomposed into Cu+ and/or Cu0 species during reaction, which further influenced the ethanol selectivity (38.4 wt%).
Ionic Liquid‐Encapsulated Zeolite Catalysts for the Conversion of Glucose to 5‐Hydroxymethylfurfural
Authors: Saxena Pooja , Velaga Bharath , Peela Nageswara Rao 
Published: November 2017

AbstractIonic Liquid (1‐Butyl‐3‐methylimidazolium Bromide ([BMIM]Br) or Choline Chloride (ChCl)) encapsulated zeolites (HY and H‐MOR) have been synthesized by ship‐in‐a‐bottle strategy and tested for selective conversion of glucose to 5‐Hydroxymethylfurfural (HMF). Nitrogen sorption analysis showed that the surface area and total pore volume decreased and average pore size increased significantly when the zeolites are encapsulated with ionic liquids. The major effect was found to be on the microporosity whereas the mesoporosity is affected only marginally. From Thermogravimetric Analysis it is observed that the decomposition temperature of ionic liquids increased when encapsulated in the zeolite. The catalytic tests were carried out in presence of NaCl and an extraction phase to remove the formed HMF. The test results of BMIMBr−H‐MOR indicate that even though there is a significant decrease in the surface area with encapsulation, the yield and selectivity are higher with this catalyst as compared to its bare zeolite counterpart. The effect of the addition of NaCl and extraction phase and reaction conditions such as reaction time and temperature on activity and yield of HMF are evaluated on the best catalyst. In catalyst stability study, the reasons for deactivation of catalyst are identified by post‐reaction catalyst characterizations.
Green Synthesis of 5‐Hydroxymethylfurfural from Chitosan Biomass Catalyzed by Benzimidazole‐Based Ionic Liquids
Authors: Zhang Mingchuan , Zang Hongjun , Ma Bin , Zhang Xiaolei , Xie Ruirui , Cheng Bowen 
Published: November 2017

Abstract5‐Hydroxymethylfurfural (5‐HMF) is one of the most important platform chemicals in biorefinery, which could be further converted into bio‐fuels. In this work, an effective and green route for 5‐HMF production from chitosan biomass in a dimethylsulfoxide (DMSO)/water mixed solvent using acidic ionic liquids as the catalysts is reported. Several ionic liquids were successfully synthesized and used as catalysts for the degradation of chitosan. Benzimidazolium chloride ([Hbim]Cl) exhibited the best catalytic activity. We achieved a maximum 5‐HMF yield of 34.9 mol% in 10 wt% DMSO‐water mixed solvent. Moreover, the catalyst could be easily recycled and reused at least five times without a significant loss of activity. Our investigation involved the use of recycled catalysts and crustacean waste as the starting material, which makes the process “green” and sustainable.
Glycoclusters with Additional Functionalities for Binding to the LecA Lectin from Pseudomonas aeruginosa
Authors: Angeli Anthony , Dupin Lucie , Madaoui Mimouna , Li Muchen , Vergoten Gérard , Wang Shuai , Meyer Albert , Géhin Thomas , Vidal Sébastien , Vasseur Jean‐Jacques , Chevolot Yann , Morvan François 
Published: November 2017

AbstractDue to the ability of Pseudomonas aeruginosa (PA) to develop antibiotic resistances, alternative therapeutic strategies have been proposed. Among others, carbohydrate multivalent molecules targeting lectin‐based virulent factors have been widely reported in particular those targeting LecA. LecA is a tetravalent galactose specific lectin involved in biofilm formation and cell internalization. Herein, we report the synthesis of 36 galactoclusters built from galactosides with aromatic and non‐aromatic aglycons and with an additional chain. The chains were either neutral or positively charged. Only the galactoclusters with naphthyl or tyrosine aglycon showed a moderate increase of binding for the positively charged 3‐dimethylammonium propyl chain. In contrast, the non‐aromatic galactoclusters display typically poorer binding properties towards LecA. The introduction of these side chains led to improved affinities up to becoming comparable to the high‐affinity aromatic galactoclusters.
A Facile and Green Approach for the One‐Pot Multicomponent Synthesis of 2,4,5‐Triaryl‐ and 1,2,4,5‐Tetraarylimidazoles by Using Zinc‐Proline Hybrid Material as a Catalyst
Authors: Agarwal Shalini , Kidwai Mazaahir , Poddar Roona , Nath Mahendra 
Published: November 2017

AbstractA concise, green, highly versatile and selective one‐pot synthesis of 2,4,5‐triarylimidazoles and 1,2,4,5‐tetraarylimidazoles is reported in this paper. This methodology involves the condensation of bezil or benzoin with various aldehydes and ammonium acetate or aromatic amines in water : ethanol (4:1) mixture containing zinc‐proline hybrid material (ZnPHM) as catalyst to afford various triaryl and tetraarylimidazoles. The facile and mild protocol eliminates the use of expensive and corrosive reagents, toxic solvents and ensures operational simplicity with easy workup. The prominent features of this protocol are avoidance of harsh reaction conditions, recyclability of the catalyst and excellent yields of the desired products after simple crystallization.
Development of Endothelial Cell Networks in 3D Tissues by Combination of Melt Electrospinning Writing with Cell‐Accumulation Technology
Authors: Bertlein Sarah , Hikimoto Daichi , Hochleitner Gernot , Hümmer Julia , Jungst Tomasz , Matsusaki Michiya , Akashi Mitsuru , Groll Jürgen 
Published: November 2017

AbstractA remaining challenge in tissue engineering approaches is the in vitro vascularization of engineered constructs or tissues. Current approaches in engineered vascularized constructs are often limited in the control of initial vascular network geometry, which is crucial to ensure full functionality of these constructs with regard to cell survival, metabolic activity, and potential differentiation ability. Herein, the combination of 3D‐printed poly‐ε‐caprolactone scaffolds via melt electrospinning writing with the cell‐accumulation technique to enable the formation and control of capillary‐like network structures is reported. The cell‐accumulation technique is already proven itself to be a powerful tool in obtaining thick (50 µm) tissues and its main advantage is the rapid production of tissues and its ease of performance. However, the applied combination yields tissue thicknesses that are doubled, which is of outstanding importance for an improved handling of the scaffolds and the generation of clinically relevant sample volumes. Moreover, a correlation of increasing vascular endothelial growth factor secretion to hypoxic conditions with increasing pore sizes and an assessment of the formation of neovascular like structures are included.
Rhombic‐Shaped Nanostructures and Mechanical Properties of 2D DNA Origami Constructed with Different Crossover/Nick Designs
Authors: Ma Zhipeng , Huang Yunfei , Park Seongsu , Kawai Kentaro , Kim Do‐Nyun , Hirai Yoshikazu , Tsuchiya Toshiyuki , Yamada Hirofumi , Tabata Osamu 
Published: November 2017

AbstractDNA origami methods enable the fabrication of various nanostructures and nanodevices, but their effective use depends on an understanding of their structural and mechanical properties and the effects of basic structural features. Frequency‐modulation atomic force microscopy is introduced to directly characterize, in aqueous solution, the crossover regions of sets of 2D DNA origami based on different crossover/nick designs. Rhombic‐shaped nanostructures formed under the influence of flexible crossovers placed between DNA helices are observed in DNA origami incorporating crossovers every 3, 4, or 6 DNA turns. The bending rigidity of crossovers is determined to be only one‐third of that of the DNA helix, based on interhelical electrostatic forces reported elsewhere, and the measured pitches of the 3‐turn crossover design rhombic‐shaped nanostructures undergoing negligible bending. To evaluate the robustness of their structural integrity, they are intentionally and simultaneously stressed using force‐controlled atomic force microscopy. DNA crossovers are verified to have a stabilizing effect on the structural robustness, while the nicks have an opposite effect. The structural and mechanical properties of DNA origami and the effects of crossovers and nicks revealed in this paper can provide information essential for the design of versatile DNA origami structures that exhibit specified and desirable properties.
Self‐Organization of Amorphous Carbon Nanocapsules into Diamond Nanocrystals Driven by Self‐Nanoscopic Excessive Pressure under Moderate Electron Irradiation without External Heating
Authors: Wang Chengbing , Ling San , Yang Jin , Rao Dewei , Guo Zhiguang 
Published: November 2017

AbstractPhase transformation between carbon allotropes usually requires high pressures and high temperatures. Thus, the development of low‐temperature phase transition approaches between carbon allotropes is highly desired. Herein, novel amorphous carbon nanocapsules are successfully synthesized by pulsed plasma glow discharge. These nanocapsules are comprised of highly strained carbon clusters encapsulated in a fullerene‐like carbon matrix, with the formers serving as nucleation sites. These nucleation sites favored the formation of a diamond unit cell driven by the self‐nanoscopic local excessive pressure, thereby significantly decreasing the temperature required for its transformation into a diamond nanocrystal. Under moderate electron beam irradiation (10–20 A cm−2) without external heating, self‐organization of the energetic carbon clusters into diamond nanocrystals is achieved, whereas the surrounding fullerene‐like carbon matrix remains nearly unchanged. Molecular dynamics simulations demonstrate that the defective rings as the active sites dominate the phase transition of amorphous carbon to diamond nanocrystal. The findings may open a promising route to realize phase transformation between carbon allotropes at a lower temperature.
Emission Tuning with Size‐Controllable Polymer Dots from a Single Conjugated Polymer
Authors: Kim Jongho , Lee Taek Seung 
Published: November 2017

AbstractTwo conjugated polymers (CPs) with various compositions of phenylene and benzoselenadiazoben (BSD) are synthesized to have a special emitting property; different fluorescence colors in solution and in the solid states, allowing the resulting conjugated polymer dots (Pdots) to emit different fluorescence colors upon their size variation. The photophysical property of such different‐sized Pdots is investigated using fluorescence spectra and fluorescence lifetimes. A decrease in the fluorescence lifetime of Pdots is observed with an increase in the size of Pdots, caused by quantitative change in energy transfer from phenylene (energy donor) to the BSD unit (energy acceptor). The results provide that any CP can be used for the fabrication of Pdots with size‐tunable emission, as long as the CP shows different emissions according to its phases. Such emission of Pdots can even be observed when in the solid solution in polymer matrix, which emits different fluorescence colors depending on the size of embedded Pdots in the polymer matrix.
Wavy Architecture Thin‐Film Transistor for Ultrahigh Resolution Flexible Displays
Authors: Hanna Amir Nabil , Kutbee Arwa Talal , Subedi Ram Chandra , Ooi Boon , Hussain Muhammad Mustafa 
Published: November 2017

AbstractA novel wavy‐shaped thin‐film‐transistor (TFT) architecture, capable of achieving 70% higher drive current per unit chip area when compared with planar conventional TFT architectures, is reported for flexible display application. The transistor, due to its atypical architecture, does not alter the turn‐on voltage or the OFF current values, leading to higher performance without compromising static power consumption. The concept behind this architecture is expanding the transistor's width vertically through grooved trenches in a structural layer deposited on a flexible substrate. Operation of zinc oxide (ZnO)‐based TFTs is shown down to a bending radius of 5 mm with no degradation in the electrical performance or cracks in the gate stack. Finally, flexible low‐power LEDs driven by the respective currents of the novel wavy, and conventional coplanar architectures are demonstrated, where the novel architecture is able to drive the LED at 2 × the output power, 3 versus 1.5 mW, which demonstrates the potential use for ultrahigh resolution displays in an area efficient manner.
Kolmogorov–Zurbenko filters in spatiotemporal analysis
Authors: Zurbenko Igor G. , Smith Devin 
Published: November 2017

This paper is an extension of WIRE publication Kolmogorov–Zurbenko filters, 2010. It addresses computational aspects of multidimensional KZ filtering for unevenly spaced data. Some real examples are provided to illustrate some of the details of such data analysis. The identification and separation of different spatial or temporal scales in spatiotemporal data can provide essential improvements to the accuracy of explanations. In particular, long term scales can be made to display clear patterns which are absolutely indistinguishable using standard multivariate analysis methods. WIREs Comput Stat 2018, 10:e1419. doi: 10.1002/wics.1419This article is categorized under:

Applications of Computational Statistics > Signal and Image Processing and Coding
Data: Types and Structure > Image and Spatial Data
Data: Types and Structure > Time Series, Stochastic Processes, and Functional Data
Objective Evaluation of Gastroesophageal Reflux Disease in Patients with Paroxysmal Atrial Fibrillation
Authors: Coutinho Enia Lucia , Herbella Fernando A. M. , Lovato Carlos Alexandre Volponi , Patti Marco G. , Schlottmann Francisco , de Paola Angelo Amato Vincenzo 
Published: November 2017

AbstractBackgroundAtrial fibrillation (AF) is the most common cardiac arrhythmia. Some evidence shows that gastroesophageal reflux disease (GERD) may be a trigger for paroxysmal AF (PAF). Most of the previous studies that correlated GERD and AF used questionnaires to diagnose GERD, not an objective evaluation. This study aims to evaluate in patients with PAF: (a) accuracy of symptoms to diagnose GERD; (b) prevalence of GERD; and (c) temporal correlation between cardiac arrhythmia and reflux.MethodsTwenty‐two patients (59% females, mean age 68 years) with PAF underwent esophageal manometry followed by ambulatory pH monitoring and concurrent Holter. Eight (36%) patients had GERD symptoms. Patients were grouped as GERD+ or GERD− based on the DeMeester score. Temporal correlation between arrhythmia and reflux was recorded.ResultsSix (27%) patients were GERD+. Symptoms had sensitivity and specificity of 50 and 70%, respectively, for the diagnosis of GERD. Episodic AF occurred in one patient only (GERD−). There were 23 episodes of AF during the test with 14% correlation with reflux. Persistent AF during the period of the test was found in five patients (60% GERD+).ConclusionsOur results show: (a) Symptoms have a low accuracy for the diagnosis of GERD; (b) the prevalence of GERD in patients with PAF is low; and (c) temporal correlation between episodes of reflux and cardiac arrhythmia is low.