bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aplicações potenciais da Linguística Cognitiva para áreas da Linguagem, do Discurso e da Gramática
Authors: Abreu Antônio Suárez , Lopes Thiago Wallace Rodrigues dos Santos , Leão Débora 
Published: September 2024

A entrevista nacional do dossiê "A relação 'língua e sentido' em diferentes abordagens", da Palimpsesto – revista discente do Programa de Pós-Graduação em Letras da UERJ, oportuniza uma troca com o professor, pesquisador e escritor Antônio Suarez de Abreu. Doutor em Linguística pela Universidade de São Paulo (USP), atuou em diversas universidades, como USP e UNESP, tem experiência e produção nas áreas de Cognição e Linguagem, Gramática e Retórica e Linguística Cognitiva. Nessa conversa, fomos brindados com o seu percurso dentro dos estudos linguísticos, discorrendo sobre assuntos como a produção de textos, marcadores textuais e pragmáticos e, com maior destaque, Linguística Cognitiva, assunto que conduz nosso foco para um homem não (apenas) científico, mas ancestral e corporificado. Agradecemos imensamente ao professor Antônio Suarez de Abreu pela proveitosa conversa.
Minimally invasive robotic-assisted lumbar laminectomy
Authors: Altorfer Franziska C. S. , Kelly Michael J. , Avrumova Fedan , Burkhard Marco D. , Sneag Darryl B. , Chazen J. L. , Tan Ek T. , Lebl Darren R. 
Published: September 2024

AimsTo report the development of the technique for minimally invasive lumbar decompression using robotic-assisted navigation.MethodsRobotic planning software was used to map out bone removal for a laminar decompression after registration of CT scan images of one cadaveric specimen. A specialized acorn-shaped bone removal robotic drill was used to complete a robotic lumbar laminectomy. Post-procedure advanced imaging was obtained to compare actual bony decompression to the surgical plan. After confirming accuracy of the technique, a minimally invasive robotic-assisted laminectomy was performed on one 72-year-old female patient with lumbar spinal stenosis. Postoperative advanced imaging was obtained to confirm the decompression.ResultsA workflow for robotic-assisted lumbar laminectomy was successfully developed in a human cadaveric specimen, as excellent decompression was confirmed by postoperative CT imaging. Subsequently, the workflow was applied clinically in a patient with severe spinal stenosis. Excellent decompression was achieved intraoperatively and preservation of the dorsal midline structures was confirmed on postoperative MRI. The patient experienced improvement in symptoms postoperatively and was discharged within 24 hours.ConclusionMinimally invasive robotic-assisted lumbar decompression utilizing a specialized robotic bone removal instrument was shown to be accurate and effective both in vitro and in vivo. The robotic bone removal technique has the potential for less invasive removal of laminar bone for spinal decompression, all the while preserving the spinous process and the posterior ligamentous complex. Spinal robotic surgery has previously been limited to the insertion of screws and, more recently, cages; however, recent innovations have expanded robotic capabilities to decompression of neurological structures.Cite this article: Bone Jt Open 2024;5(9):809–817.
Metricisation in school: an affective and epistemic injustice
Authors: Lynch Kathleen , Lodge Anne 
Published: September 2024

Neither the Rawlsian distributive model of justice nor Fraser’s (2008) three-dimensional model, based on principles of redistribution, recognition and representation, are sufficient to explain inequality in education. Both perspectives misrecognise how affective care relations operate as a discrete and relatively autonomous set of social practices, and how epistemic injustices impact participatory parity. The goal of this article is to show how metricisation exacerbates both affective and epistemic injustices, which, in turn, compound the classism and ableism of education.
Being hierarchically classified in school means being future-framed by a series of life-defining metrics specifying your capabilities. For many, the result is a definition that sets them apart as lacking appropriate educational currency (cleverness) defined in terms of abstract verbal and logical-mathematical reasoning. This exposes them to public shaming and humiliation, which, while exacerbated by tracking, works independently alongside it. The cleverness devaluation provides a moral and political justification for hierarchical ordering, an ordering that is incontestable as children lack epistemic credibility.
Drawing on published research examining the impact of rating and grading children in school, and on a reanalysis of data from a major study of inequality in education undertaken by the authors, the article examines affective and epistemic injustices and the role of metrics in these processes. A key message of the article is that the use of tests and metrics purporting to determine and order children’s educational ‘ability’ or ‘intelligence’ leads to the hierarchical ordering that is deeply unjust in affective terms, and compounded by testimonial and hermeneutic injustices in school.
The association between frailty, care receipt and unmet need for care with the risk of hospital admissions
Authors: Maharani Asri , Sinclair David R. , Clegg Andrew , Hanratty Barbara , Nazroo James , Tampubolon Gindo , Todd Chris , Wittenberg Raphael , O’Neill Terence W. , Matthews Fiona E. 
Published: September 2024

Background
Frailty is characterised by a decline in physical, cognitive, energy, and health reserves and is linked to greater functional dependency and higher social care utilisation. However, the relationship between receiving care, or receiving insufficient care among older people with different frailty status and the risk of unplanned admission to hospital for any cause, or the risk of falls and fractures remains unclear.

Methods and findings
This study used information from 7,656 adults aged 60 and older participating in the English Longitudinal Study of Ageing (ELSA) waves 6–8. Care status was assessed through received care and self-reported unmet care needs, while frailty was measured using a frailty index. Competing-risk regression analysis was used (with death as a potential competing risk), adjusted for demographic and socioeconomic confounders. Around a quarter of the participants received care, of which approximately 60% received low levels of care, while the rest had high levels of care. Older people who received low and high levels of care had a higher risk of unplanned admission independent of frailty status. Unmet need for care was not significantly associated with an increased risk of unplanned admission compared to those receiving no care. Older people in receipt of care had an increased risk of hospitalisation due to falls but not fractures, compared to those who received no care after adjustment for covariates, including frailty status.

Conclusions
Care receipt increases the risk of hospitalisation substantially, suggesting this is a group worthy of prevention intervention focus.
Mixed Cellular and Antibody-Mediated Rejection—A Rare yet Morbid Occurrence
Authors: Chiodi Cristina , Tiwari Harsh , Bak Esther , Royer Amor , Jophlin Loretta , Marsano Luis 
Published: September 2024

ABSTRACT
Liver transplantation remains the definitive treatment for end-stage liver disease, yet rejection of the transplanted organ poses a significant challenge to long-term graft survival. We present a case of a 47-year-old woman who underwent liver transplantation for primary sclerosing cholangitis. Following the procedure, the patient experienced a rare phenomenon of dual rejection, characterized by both acute cellular rejection and antibody-mediated rejection. Despite initial immunosuppressive therapy, the patient's condition deteriorated. Histopathological examination revealed concurrent signs of acute cellular rejection and antibody-mediated rejection, highlighting the complexity of immune response in allograft rejection. Management involved intensified immunosuppression targeting both T-cell-mediated and antibody-mediated pathways, along with plasmapheresis to remove circulating antibodies. This case highlights an atypical presentation of rejection after transplantation. Further research is warranted to elucidate the underlying mechanisms and optimal management approaches for dual rejection in liver transplantation.
Biliary Colonic Fistula Formation in the Setting of Obstructive Cholelithiasis
Authors: Mushtaq Muhammad , Khan Ayesha , Tran Minh , Walker John , Parupudi Sreeram 
Published: September 2024

ABSTRACT
Biliary enteric fistulas are rare form of internal biliary fistula encountered in <1% of patients with biliary disease while cholecystocolic fistulas are even rarer with reported incidence of 0.06%–0.14% in patients undergoing cholecystectomy. We present a case of biliary colonic fistula that developed in the context of obstructive cholelithiasis, emphasizing a pathological process involving chronic inflammation due to gallstone with a gradual erosion into the surrounding structure. A high index of suspicion is required for diagnosis, given the presentation with nonspecific symptoms. Given the risk of imminent cholangitis, sepsis, and liver parenchymal damage, early treatment with cholecystectomy with the closure of the fistula is recommended.
Autoimmune Hemolytic Anemia From Tofacitinib Use in a Patient With Ulcerative Colitis
Authors: Zisman Erin , Bashir-Hamidu Rukaiya , George Lauren 
Published: September 2024

ABSTRACT
Tofacitinib is a Janus kinase inhibitor commonly used in the management of rheumatoid arthritis and moderate-to-severe ulcerative colitis. Anemia is a rare side effect of this medication often with minimal changes in hemoglobin levels. We report the first case of autoimmune hemolytic anemia from tofacitinib use in a patient with inflammatory bowel disease. This patient developed transfusion-dependent anemia after the initiation of tofacitinib and underwent extensive workup that revealed a diagnosis of autoimmune hemolytic anemia. The medication was discontinued, and she was treated with steroids and rituximab, leading to the improvement and stabilization of her hemoglobin levels.
Type 2 amiodarone-induced thyrotoxicosis: factors of delayed response to glucocorticoid therapy
Authors: Ermolaeva A. S. , Fadeev V. V. 
Published: September 2024

BACKGROUND. Glucocorticoids are first-line drugs for the treatment of amiodarone-induced destructive thyroiditis. Due to the progression of left ventricular dysfunction, recurrence of rhythm disturbances and increased risk of adverse cardiovascular outcomes in this cohort of patients, rapid restoration of euthyroidism, especially in the elderly, is crucial. However, it is not always feasible with the drug therapy, because the time to achieve euthyroidism is unpredictable in each individual case. Identification of factors that allow predicting the efficacy and duration of glucocorticoid therapy will help to determine the correct tactics of patient management.AIM. To identify factors of delayed response to glucocorticoid therapy in patients with type 2 amiodarone-induced thyrotoxicosis.MATERIALS AND METHODS. The study included 11 retrospective and 22 prospective patients aged 30 to 80 years (21 men and 12 women) with verified type 2 amiodarone-induced thyrotoxicosis, who received prednisolone therapy at a starting dose of 30 mg/day. Anamnestic, anthropometric data, results of laboratory and instrumental diagnostics were analyzed. The follow-up period of patients was 1–5 years. The effecasy of therapy was evaluated by the time to achieve euthyroidism, duration of thyrotoxicosis, frequency of repeated waves of destruction and relapses.RESULTS. The average age of the patients was 57.0 [52.0; 66.0] years. After 1 month (30 days) from the start of glucocorticoid therapy, euthyroidism was achieved in 17/33 (51.5%) patients, pfT4GK-fT4GK1month<0.001, pfT3GK-fT3GK1month<0.001. Delayed achievement of euthyroidism (>30 days) was observed in 48.5% of patients. The median time to achieve euthyroidism was 72.0±3.0 (95% CI: 66.1–77.9) days, the average time was 86.9±13.4 (95% CI: 60.6–113.1) days. The median duration of thyrotoxicosis was 120.0±22.1 (95% CI: 76.6—163.4) days, the average time was 137.8±15.6 (95% CI: 107.2–168.4) days. The level of free thyroxine after 30 days of therapy depended on the interval «clinical symptoms — laboratory confirmation» (R2=0.120, p=0.049). Time to achieve euthyroidism depended on age (R2=0.185; p=0.013). Age was also a predictor of repeated waves of destruction (OR=0.833, 95% CI:0.709–0.978; R2=0.428, p=0.025).CONCLUSION. Age is a predictive factor for the time to achieve euthyroidism in type 2 amiodarone-induced thyrotoxicosis.
A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation
Authors: Schultes Fabian Peter Josef , Welter Leon , Schmidtke Myra , Tischler Dirk , Mügge Carolin 
Published: September 2024

Abstract
Cytochrome P450 monooxygenases are recognized as versatile biocatalysts due to their broad reaction capabilities. One important reaction is the hydroxylation of non-activated C–H bonds. The subfamily CYP153A is known for terminal hydroxylation reactions, giving access to functionalized aliphatics. Whilst fatty derivatives may be converted by numerous enzyme classes, midchain aliphatics are seldomly accepted, a prime property of CYP153As. We report here on a new CYP153A member from the genome of the mesophilic actinobacterium Gordonia rubripertincta CWB2 as an efficient biocatalyst. The gene was overexpressed in Escherichia coli and fused with a surrogate electron transport system from Acinetobacter sp. OC4. This chimeric self-sufficient whole-cell system could perform hydroxylation and epoxidation reactions: conversions of C6–C14 alkanes, alkenes, alcohols and of cyclic compounds were observed, yielding production rates of, e.g., 2.69 mM h−1 for 1-hexanol and 4.97 mM h−1 for 1,2-epoxyhexane. Optimizing the linker compositions between the protein units led to significantly altered activity. Balancing linker length and flexibility with glycine-rich and helix-forming linker units increased 1-hexanol production activity to 350 % compared to the initial linker setup with entirely helical linkers. The study shows that strategic coupling of efficient electron supply and a selective enzyme enables previously challenging monooxygenation reactions of midchain aliphatics.
Bidirectional high-speed optical wireless communication with tunable large field of view assisted by liquid crystal metadevice
Authors: Wu Mian , Yang Chao , Gong Yuhan , Wu Lin , Luo Ming , Qiu Ying , Zeng Yongquan , Li Zile , Liu Zichen , Li Chao , Li Hanbing , Xiao Xi , He Zhixue , Zheng Guoxing , Yu Shaohua , Tao Jin 
Published: September 2024

Abstract
Beam-steered infrared (IR) light communication has gained tremendous attention as one of the solutions of congested wireless communication traffic. High performance active beam-steering devices play a crucial role in data allocation and exchange. Conventional beam-steering devices such as spatial light modulator (SLM) and micro-electrical mechanical system (MEMS) mirror and the current emerging nonmechanical beam-steering metasurface-based devices are challenging to realize a large tunable steering angle beyond several degrees, which significantly hinders the spatial application of optical wireless communications (OWC). Herein, an angle-magnified liquid crystal (LC) metadevice consisting of LC metasurfaces and a liquid crystal on silicon (LCoS) is proposed to realize active beam steering with a tunable large field of view (FOV). Based on the angle-magnified tunable LC metadevice, an intelligent bidirectional high-speed OWC system is experimentally demonstrated, achieving an actively enlarged FOV of 20° × 20°, with a data rate of 200 Gbps over the S/C/L band for both uplink and downlink transmission over a propagation distance of 1.5 m in free space. The proposed OWC system opens a new avenue for the future high performance wireless data transmission.
Determinants of health insurance adoption among residents of Lagos, Nigeria: A cross-sectional survey
Authors: Adeniran Adeyinka , Wright Kikelomo Ololade , Aderibigbe Adedayo , Akinyemi Olufunsho , Fagbemi Temiloluwa , Ayodeji Omoyeni , Adepase Abiola , Zamba Emmanuella , Abdur-Razzaq Hussein , Oniyire Faith , Ogboye Olusegun , Abayomi Akin 
Published: September 2024

Abstract

Introduction
This study assessed health insurance uptake, and payment preferences for health insurance enrollment, and identified barriers and facilitators of the utilization of health insurance amongst residents in Lagos State.

Methodology
The study employed a cross-sectional survey design to gather data from 2,490 residents across four local government areas in Lagos State, Nigeria, between December 2022 and March 2023. Participants were selected through a multistage sampling technique, and data were collected using pre-tested, semi-structured questionnaires. The analysis comprised univariate, bivariate, and binary logistic regression analyses, performed using the STATA 15.0 software package. The level of statistical significance was set at P < 0.05, and 95% confidence intervals were calculated for the adjusted odds ratios.

Results
Awareness of health insurance was generally average among respondents (54.4%) and extremely few respondents (10.9%) had ever been enrolled in one form of health insurance or the other. The private health insurance schemes were the most frequently patronized scheme (58.5%) while the Lagos State-owned scheme was patronized by less than one-fifth (15.9%) of respondents. The need to prevent a catastrophic health event (56.3%) and compulsion at the workplace (13.1%) were the main facilitators of health insurance uptake while financial constraints (10%) and a general lack of belief in the concept of health insurance (6%) were major barriers that prevented enrollment. Age, employment status, level of education, income, occupation, and rate of health morbidity were all predictors of health insurance adoption in this study (P < 0.05).

Conclusion
Heightened awareness campaigns are necessary from both government and private entities in the health insurance sector. Additionally, the government should enforce mandatory enrollment in health insurance schemes in order to boost insurance coverage across the population.
Retroactivity in Science: Latour, Žižek, Kuhn
Authors: Harman Graham 
Published: September 2024

Abstract
This article discusses three recent philosophers who speak in different ways about the retroactive construction of reality by human knowledge. Bruno Latour unapologetically claims that the Egyptian Pharaoh Ramses II could not have died of tuberculosis, as determined by a team of French doctors in 1976, since this disease was not discovered until three thousand years after his death. Slavoj Žižek often makes comparable arguments, though his version of retroactivity draws on both psychoanalysis and dialectics in a way that is never the case for Latour. Yet in his 2012 book Less Than Nothing, Žižek takes the more prudent, realist-sounding line that changes in scientific theories do not change nature itself. The real novelty in retroactive theories is provided by Thomas Kuhn, who draws our attention to a grey temporal zone in scientific discovery in which it is impossible to pinpoint the exact date of any breakthrough. For Kuhn, this stems from a dualism found in reality itself: one between the fact “that” a thing exists and the determination of “what” its properties are. The tension between these two moments is responsible for much of the vagueness and drama surrounding any paradigm shift in the sciences and is closely related to at least one plausible theory of metaphor. In closing, three Hollywood films are cited as helpful examples for understanding the different ways in which a paradigm shift works its retroactive magic.
From ‘low-class’ and ‘talentless’ to ‘narcissist and pathological liar’: a functional-pragmatic approach to Meghan Markle’s negative evaluation on X
Authors: del Saz-Rubio Mᵃ Milagros 
Published: September 2024

Abstract
This paper looks into how aggression against Meghan Markle is deployed in a sample of X replies that address her directly through the lens of Appraisal Theory coupled with impoliteness. A sample of tweets containing the seed word “Meghan Markle” was retrieved with Export Comments (December 2022–April 2023). Replies were run through the Linguistic Inquiry and Word Count-22 to assess the tone and prevalence of emotions in the corpus. Results indicated high values for negative emotions, interpersonal conflict, and moralization words. Then, a random sample was manually codified to identify the use frequencies for the Attitude system’s affect, judgment, and appreciation categories when employed to convey hostility against the public figure. Tweets were overwhelmingly negative and explicitly conveyed through the negative judgment of Meghan Markle’s previous sexual and professional life. The veracity of her words and actions was also a source of aggression while tapping into the widely accepted stereotype that depicts women as liars or as incompetent and lacking determination, while some tweets also touched upon her mental instability. Findings reveal that aggressive tweets on X rely on appraisal resources and impolite-related language to promote and perpetuate culturally bound and traditional beliefs about women that ultimately reflect an underlying patriarchal system.
Temporal ‘since’ constructions in cross-linguistic perspective
Authors: Olguín Martínez Jesús , Vásquez-Aguilar Alonso , Valenzuela Pilar 
Published: September 2024

Abstract
The paper offers an analysis of the cross-linguistic variation in the expression of clausal temporal ‘since’ relations (e.g., I have been working since you arrived) in a sample of 59 languages. First, the investigation explores whether clausal temporal ‘since’ constructions bear formal resemblance to nominal temporal ‘since’ constructions (e.g., It has been raining since yesterday), nominal beginning-to-end constructions (e.g., They will sleep from tonight to tomorrow), and clausal beginning-to-end constructions (e.g., From the moment they were born, until they died, they never paid their bills). While, in most languages in the sample, these constructions are formed with the same pattern, the paper shows that there may be more to the story. Second, it is shown that at least one of the markers encoding nominal beginning-to-end constructions tends to be simpler (in terms of the number of segments) than the markers found in clausal temporal ‘since’ constructions or clausal ‘until’ constructions. It is proposed that this is the result of economy.