bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seasonal Effectiveness of Live Attenuated and Inactivated Influenza Vaccine
Authors: Chung Jessie R. , Flannery Brendan , Thompson Mark G. , Gaglani Manjusha , Jackson Michael L. , Monto Arnold S. , Nowalk Mary Patricia , Talbot H. Keipp , Treanor John J. , Belongia Edward A. , Murthy Kempapura , Jackson Lisa A. , Petrie Joshua G. , Zimmerman Richard K. , Griffin Marie R. , McLean Huong Q. , Fry Alicia M. 
Published: January 2016

BACKGROUND:
Few observational studies have evaluated the relative effectiveness of live attenuated (LAIV) and inactivated (IIV) influenza vaccines against medically attended laboratory-confirmed influenza.

METHODS:
We analyzed US Influenza Vaccine Effectiveness Network data from participants aged 2 to 17 years during 4 seasons (2010–2011 through 2013–2014) to compare relative effectiveness of LAIV and IIV against influenza-associated illness. Vaccine receipt was confirmed via provider/electronic medical records or immunization registry. We calculated the ratio (odds) of influenza-positive to influenza-negative participants among those age-appropriately vaccinated with either LAIV or IIV for the corresponding season. We examined relative effectiveness of LAIV and IIV by using adjusted odds ratios (ORs) and 95% confidence intervals (CIs) from logistic regression.

RESULTS:
Of 6819 participants aged 2 to 17 years, 2703 were age-appropriately vaccinated with LAIV (n = 637) or IIV (n = 2066). Odds of influenza were similar for LAIV and IIV recipients during 3 seasons (2010–2011 through 2012–2013). In 2013–2014, odds of influenza were significantly higher among LAIV recipients compared with IIV recipients 2 to 8 years old (OR 5.36; 95% CI, 2.37 to 12.13). Participants vaccinated with LAIV or IIV had similar odds of illness associated with influenza A/H3N2 or B. LAIV recipients had greater odds of illness due to influenza A/H1N1pdm09 in 2010–2011 and 2013–2014.

CONCLUSIONS:
We observed lower effectiveness of LAIV compared with IIV against influenza A/H1N1pdm09 but not A(H3N2) or B among children and adolescents, suggesting poor performance related to the LAIV A/H1N1pdm09 viral construct.
Compromiso y esperanza en educación: Los ejes transversales para la práctica docente según Paulo Freire
Authors: García-Retana José Ángel 
Published: January 2016

<p>Pedagogía de la autonomía es un texto donde Freire aborda cómo todo acto educativo es un acto político e ideológico, condicionado pero no determinado, que va más allá de la simple transmisión de conocimientos. Considera los saberes requeridos para la práctica docente y detalla al menos cinco ejes transversales: la relación dialéctica entre aprender y enseñar, la importancia de tomar en cuenta los aspectos emocionales, el carácter político que encierra, enseñar es más que transmitir información y el compromiso ético del personal docente. Aduce que la práctica educativa como acto político es deliberado y depende de la visión de mundo (ideología) que tenga cada docente. Tal acto debe conllevar el desarrollo de una intencionalidad: la autonomía del educando. Freire prevé el proceso de globalización y el impacto de las tecnologías digitales en el campo educativo y advierte sobre la intencionalidad de dicho proceso: subordinar la educación en calidad de apéndice de la economía. Por lo anterior, apela a considerar la práctica educativa como una relación dialéctica, holística, humanista, ética, donde tanto aprenden como enseñan quienes participan de ella, lo que permite plantear que la educación abre la esperanza a un mundo mejor.</p><p> </p>
Dynamic recrystallization kinetics in Mg-3Gd-1Zn magnesium alloy during hot deformation
Authors: Mirzadeh Hamed , Roostaei Milad , Parsa Mohammad Habibi , Mahmudi Reza 
Published: January 2016

AbstractThe initiation of dynamic recrystallization during hot deformation, its kinetics according to the Johnson–Mehl–Avrami–Kolmogorov model, and the resultant grain refinement in the Mg-3Gd-1Zn magnesium alloy were studied to elucidate the mechanism of dynamic recrystallization and the opportunities it offers during high-temperature thermomechanical processing of this heat resistant light alloy. The necklace mechanism was found to be responsible for the noticeable grain refinement, during which the mean recrystallized grain size varied slightly. These results were further confirmed based on the kinetics analysis.
Global modeling for elevated temperature flow behavior of 6013 aluminum alloy during two-pass deformation
Authors: Xiao Gang , Yang Qinwen , Li Luoxing , He Huan 
Published: January 2016

AbstractTwo-pass hot plane strain compression tests of 6013 aluminum alloy were conducted at different temperatures, strain rates, and holding times. Using the experimental data, four popular metamodel types – Kriging, radial basis function, polynomial regression and artificial neural network – were investigated as potential methods for global modeling of the flow behavior during two-pass deformation. The global model developed from the Kriging method was superior in terms of the accuracy and stability of the prediction. Furthermore, this model was successfully used to predict not only the two-pass deformation behavior beyond the experimental conditions, but also the multipass deformation behavior. It is proved that the Kriging method is an effective and reliable approach to develop a global model for optimization of the hot forming process.
Human Head and Neck Squamous Cell Carcinoma–Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells
Authors: Younis Rania H. , Han Kyu Lee , Webb Tonya J. 
Published: January 2016

AbstractOne of the mechanisms by which malignancies can induce immune suppression is through the production of cytokines that affect the maturation and differentiation of inflammatory cells in the tumor microenvironment. Semaphorin 4D (Sema4D) is a proangiogenic cytokine produced by several malignancies, which has been described in the regulation of the immune system. In the present study, we examined the role of human head and neck squamous cell carcinoma (HNSCC)–secreted Sema4D on myeloid cell differentiation. CD33+ cells cultured in HNSCC cell line–derived conditioned medium differentiated into myeloid derived suppressor cells (MDSC) (CD33+CD11b+HLA-DR−/low). The addition of anti-Sema4D Ab to HNSCC conditioned medium significantly reduced the expansion of the MDSC population. Similarly, knockdown of Sema4D in an HNSCC cell line resulted in a loss of MDSC function as shown by a decrease in the production of the immune-suppressive cytokines arginase-1, TGF-β, and IL-10 by MDSC, concomitant with recovery of T cell proliferation and IFN-γ production following stimulation of CD3/CD28. Importantly, CD33+ myeloid and T cells cultured in conditioned medium of HNSCC cells in which Sema4D was knocked down promoted antitumor inflammatory profile, through recovery of the effector T cells (CD4+T-bet+ and CD8+T-bet+), as well as a decrease in regulatory T cells (CD4+CD25+FOXP3+). We also showed that Sema4D was comparable to GM-CSF in its induction of MDSC. Collectively, this study describes a novel immunosuppressive role for Sema4D in HNSCC through induction of MDSC, and it highlights Sema4D as a therapeutic target for future studies to enhance the antitumorigenic inflammatory response in HNSCC and other epithelial malignancies.
Guías móviles en Realidad Virtual para la interpretación del patrimonio. Un caso práctico: Ruta del Megalitismo de Gorafe
Authors: Arambarri Basáñez Jon , Baeza Santamaría Unai , López Marcos Antonio 
Published: January 2016

<p>Although early prehistoric findings belong to Middle Paleolithic (30,000 to 50,000 years ago), it was 6,000 years ago when Gorafe Valley was occupied by tribes characterized by collective burials in tombs made of big blocks, that is, in dolmens (Megalithic culture of Middle Neolithic). Nowadays, Gorafe holds the biggest proportion of dolmens in Europe: 198 spread in the 10 necropolis that surround the village. The city council of Gorafe expresses the need to know and interpret<br />these dolmens through a mobile device which does not require Internet connection. This way, visitors will be able to enjoy and interpret their Megalithic tour when they visit Sierra Nevada.</p>
Reconstrucción Infográfica del Castellum de Tamuda (Tetuán, Marruecos)
Authors: Bermejo Meléndez Javier , Campos Carrasco Juan Manuel , Delgado Aguilar Salvador , Fernández Sutilo Lucía , Toscano Pérez Clara , Verdugo Santos Javier 
Published: January 2016

<p>The last researches developed in the lot of Tamuda's Roman castellum (Tetuan, Morocco), specially centred on the doors of the military installation, have emphasized different phases or constructive episodes in the life of the same one. This way in this work they present diverse restitutions infographics corresponding to the phases documented in the enclosure, centred of a specific way in the doors of access, offering an image of the evolution of the above mentioned military installation throughout almost four centuries, from the moments of the foundation in epoch of Claudio up to the beginnings of Vst. c. A.D.</p>
"Que enloquezcan mis personajes, no yo": Instancias de autoficción en la obra de Andrés Caicedo
Authors: Figueroa Carle José Gabriel 
Published: January 2016

En la escritura del colombiano Andrés Caicedo (1951 - 1977), es evidente la intención del autor en (des)articularse y desdoblarse como figura protagónica en sus (no) ficciones. Proponemos una doble lectura autoficcional de dos libros póstumos, Mi cuerpo es una celda (2008) y Calicalabozo (2008), que analice la ficcionalización de su vida en su “autobiografía” y las implicaciones autorreferenciales de su colección de cuentos. Caicedo reconstruye su laberíntica Cali natal como una extensión letrada de sí mismo, plasmando una (o varias) identidad(es) esquizofrénica(s). Su escritura misma queda poblada de espejos hostiles proyectados a través de un lente cinematográfico que documenta y ficcionaliza su entorno personal en una ciudad latinoamericana gótica y enajenante. Se considerará una multiplicidad de definiciones y modalidades de la autoficción como herramienta autoral y como género literario para demostrar cómo Caicedo elabora una leyenda de sí mismo paralela y nutrida de su escritura, un doble discurso tan insidioso e inseparable que supera hasta “la muerte del autor”.
Decisions in Search of a Doctrine: Marriage Equality in the Lower Federal Courts
Authors: Mezey Susan Gluck 
Published: January 2016

Abstract
When gay rights advocates asserted demands for equality in the courts, they found that the likelihood of a favorable outcome was tied to the standard of judicial review—known as the level of scrutiny—the courts applied to the law. “Scrutiny”is a shorthand term that describes the extent to which courts defer to majoritarian decision makers, primarily legislative bodies. The courts’ determination of the appropriate level of scrutiny—crucial to the outcome of the case—depends on the class of people challenging the law, with the courts assigning a higher level of scrutiny to laws affecting groups with insufficient clout to prevent legislation that infringes on their rights. Despite the importance of scrutiny in equal rights jurisprudence, the Supreme Court’s ruling in United States v. Windsor, invalidating the Defense of Marriage Act (DOMA), did not establish the proper level of scrutiny for laws restricting same-sex marriage. Although the lower courts overwhelmingly struck state bans on same-sex marriage in the cases following Windsor, they did so without guidance from the Supreme Court on the matter of scrutiny. This study presents key district court rulings in the post-Windsor litigation, showing that the Supreme Court’s failure to articulate its position on scrutiny provided opportunities for the lower courts to provide their own interpretation of the doctrine. Using the traditional standards for determining the level of scrutiny to apply, most concluded that it was appropriate to apply heightened scrutiny to claims based on sexual orientation. Thus, in addition to its implications for the future of marriage equality, the study also raises broader questions about the continued viability of this decades-old doctrine and the resolution of this doctrinal uncertainty.
The D.C. School Hearings of 1956 and the National Vision of Massive Resistance
Authors: Ward Jason Morgan 
Published: January 2016

Abstract
In September 1956, southern congressmen launched a hostile investigation of the District of Columbia’s recently desegregated public school system. Organized by segregationists on the House District of Columbia Committee, the school hearings and subsequent report represented a provocative attempt to stymie racial reform in the nation’s capital and beyond. By discrediting school desegregation in Washington, Deep South diehards hoped to legitimize their cause and expose white resistance north of the Mason-Dixon Line. By taking the fight to a metropolitan setting, segregationists pushed against the limits of Deep South racial politics and discovered white allies in the nation’s capital. As civil rights advocates and school officials struggled to debunk the propaganda attack, segregationists invoked Washington as a “showcase” for the folly of integration. Years before the nation’s attention drifted from southern civil rights struggles to northern racial turmoil, segregationists had anticipated and encouraged this shift by stressing common cause with the embattled whites of the metropolitan North. While their vision of a national segregationist movement never materialized, the controversy over segregation in the nation’s capital complicated notions of race and region in the civil rights era.
Flexible Temperature Sensor with High Reproducibility and Wireless Closed‐Loop System for Decoupled Multimodal Health Monitoring and Personalized Thermoregulation
Authors: Zhang Xujing , Chen Jiaxiang , Zheng Zhihao , Tang Songsong , Cheng Bin , Zhang Zhiwei , Ma Rui , Chen Zetong , Zhuo Jingting , Cao Lingyun , Chen Zhihong , He Jiangfeng , Wang Xiaofeng , Yang Guowei , Yi Fang 
Published: September 2024

AbstractTemperature and pulse waves are two fundamental indicators of body health. Specifically, thermoresistive flexible temperature sensors are one of the most applied sensors. However, they suffer from poor reproducibility of resistivity; and decoupling temperature from pressure/strain is still challenging. Besides, autonomous thermoregulation by wearable sensory systems is in high demand, but conventional commercial apparatuses are cumbersome and not suitable for long‐term portable use. Here, a material‐design strategy is developed to overcome the problem of poor reproducibility of resistivity by tuning the thermal expansion coefficient to nearly zero, precluding the detriment caused by shape expansion/shrinkage with temperature variation and achieving high reproducibility. The strategy also obtains more reliable sensitivity and higher stability, and the designed thermoresistive fiber has strain‐insensitive sensing performance and fast response/recovery time. A smart textile woven by the thermoresistive fiber can decouple temperature and pulse without crosstalk; and a flexible wireless closed‐loop system comprising the smart textile, a heating textile, a flexible diminutive control patch, and a smartphone is designed and constructed to monitor health status in real‐time and autonomously regulate body temperature. This work offers a new route to circumvent temperature‐sensitive effects for flexible sensors and new insights for personalized thermoregulation.
High‐Performance AgSbTe2 Thermoelectrics: Advances, Challenges, and Perspectives
Authors: Li Lan , Hu Boxuan , Liu Qingyi , Shi Xiao‐Lei , Chen Zhi‐Gang 
Published: September 2024

AbstractEnvironmental‐friendless and high‐performance thermoelectrics play a significant role in exploring sustainable clean energy. Among them, AgSbTe2 thermoelectrics, benefiting from the disorder in the cation sublattice and interface scattering from secondary phases of Ag2Te and Sb2Te3, exhibit low thermal conductivity and a maximum figure‐of‐merit ZT of 2.6 at 573 K via optimizing electrical properties and addressing phase transition issues. Therefore, AgSbTe2 shows considerable potential as a promising medium‐temperature thermoelectric material. Additionally, with the increasing demands for device integration and portability in the information age, the research on flexible and wearable AgSbTe2 thermoelectrics aligns with contemporary development needs, leading to a growing number of research findings. This work provides a detailed and timely review of AgSbTe2‐based thermoelectrics from materials to devices. Principles and performance optimization strategies are highlighted for the thermoelectric performance enhancement in AgSbTe2. The current challenges and future research directions of AgSbTe2‐based thermoelectrics are pointed out. This review will guide the development of high‐performance AgSbTe2‐based thermoelectrics for practical applications.
Tailoring the Compositions and Nanostructures of Trimetallic Prussian Blue Analog‐Derived Carbides for Water Oxidation
Authors: Mao Lujiao , Liu Jie , Lin Rong , Xue Jinhang , Yang Yuandong , Xu Shaojie , Li Qipeng , Qian Jinjie 
Published: September 2024

AbstractThe electrochemical splitting of water for hydrogen production faces a major challenge due to its anodic oxygen evolution reaction (OER), necessitating research on the rational design and facile synthesis of OER catalysts to enhance catalytic activity and stability. This study proposes a ligand‐induced MOF‐on‐MOF approach to fabricate various trimetallic MnFeCo‐based Prussian blue analog (PBA) nanostructures. The addition of [Fe(CN)6]3− transforms them from cuboids with protruding corners (MnFeCoPBA‐I) to core–shell configurations (MnFeCoPBA‐II), and finally to hollow structures (MnFeCoPBA‐III). After pyrolysis at 800 °C, they are converted into corresponding PBA‐derived carbon nanomaterials, featuring uniformly dispersed Mn2Co2C nanoparticles. A comparative analysis demonstrates that the Fe addition enhances catalytic activity, while Mn‐doped materials exhibit excellent stability. Specifically, the optimized MnFeCoNC‐I‐800 demonstrates outstanding OER performance in 1.0 m KOH solution, with an overpotential of 318 mV at 10 mA cm−2, maintaining stability for up to 150 h. Theoretical calculations elucidate synergistic interactions between Fe dopants and the Mn2Co2C matrix, reducing barriers for oxygen intermediates and improving intrinsic OER activity. These findings offer valuable insights into the structure‐morphology relationships of MOF precursors, advancing the development of highly active and stable MOF‐derived OER catalysts for practical applications.
Direct Growth of Wafer‐Scale Self‐Separated GaN on Reusable 2D Material Substrates
Authors: Huang Chang‐Hsun , Wu Chia‐Yi , Chou Yi‐Chia 
Published: September 2024

AbstractFree‐standing gallium nitride has been prepared using various methods; however, the removal of the original substrate is still challenging with low success rates. In this work, 2‐inch free‐standing GaN films are obtained by direct growth on a fluoro phlogopite mica by hydride vapor‐phase epitaxy. Depending on the van der Waals (vdW) interaction between GaN and mica, the effect of the significant lattice mismatch is effectively reduced; thus, enabling the production of a high‐quality wafer‐scale GaN film on mica. The vdW‐induced cracks at GaN–mica interface are found to be initiated near the interface so that GaN can easily separate from mica during rapid cooling. Owing to the hydrophilic nature of mica, the residual GaN on the mica can be lifted off by following deionized water treatment, and the mica substrate can be repeatedly used to grow free‐standing GaN films. The self‐separated GaN films grown on both pristine and used mica substrates are single crystallinity and strain‐free. Additionally, a fully functional ultraviolet light‐emitting diode is demonstrated to show that the self‐separated GaN films are of device quality. The proposed approach achieves epitaxial growth of wafer‐scale single‐crystalline GaN on 2D materials and provides a new substrate option in the technology of III‐V materials.
In Situ Self‐Polymerization of Thioctic Acid Enabled Interphase Engineering Towards High‐Performance Lithium–Sulfur Battery
Authors: Wang Liujian , Yue Ke , Qiao Qiangqiang , Zhao Zihao , Xu Yanyan , Pan Leyi , Liu Yujing , Li Hanying , Zhu Baoku 
Published: September 2024

AbstractLithium–sulfur (Li–S) batteries possess high theoretical energy density, whereas the shuttle effect of polysulfides and the uncontrollable lithium (Li) dendrites seriously reduce the reversible capacity and cycling lifespan. Constructing an interphase to address the issues in both the cathode and anode simultaneously is significant but still challenging. In this study, a strategy of functionalizing commercial polypropylene (PP) separators is proposed by in situ poly(thioctic acid) (PTA) polymerization. Compared with the conventional separator modifications, the ring‐opening polymerization methodology initiated by heat is more facile and environment‐friendly without changing the nanostructures among the porous separators. On the cathode side, the PTA‐coated separator (PTA‐PP) blocks the shuttle of polysulfides through the electrostatic interaction. On the anode side, the PTA‐coated generates a lithium fluoride (LiF)‐rich solid electrolyte interface (SEI), identified by cryo‐transmission electron microscopy (cryo‐TEM), to accelerate the Li+ diffusion and inhibit the growth of Li dendrites. Due to the interphases constructed by the PTA‐PP separator, the Li–S cells exhibit excellent long‐term cycling in which the capacity retention rate is more than 76% after 700 cycles at 0.5 C. The in situ elaborate modification strategy may provide insights into the high‐performance separator design to promote the potentially large‐scale applications of Li–S batteries.
A prospective longitudinal study assessing the impact of rhinovirus and bacterial infections in acute exacerbations of chronic rhinosinusitis
Authors: Narendran Nirushan , Volpe Sophia , Ramadan Ibrahim , Herbert Jacob Ryan , LaFleur Bonnie , Samargandy Shireen , Le Christopher H. , Chang Eugene H. 
Published: September 2024

AbstractBackgroundAcute exacerbations of chronic rhinosinusitis (AECRS) are thought to arise from common viral infections progressing to secondary bacterial infections. However, the pathophysiology of AECRS remains poorly understood due to a lack of prospective longitudinal studies.MethodsWe conducted a one‐year prospective longitudinal study involving chronic rhinosinusitis (CRS) adults. At baseline, we assessed subjective symptom scores using a validated upper respiratory infection questionnaire (WURSS), sinonasal outcome testing scores (SNOT‐22), and endoscopic scores (modified Lund‐Kennedy score). Every 2 weeks, we contacted subjects to collect WURSS and SNOT‐22 scores. If WURSS scores were ≥1 and SNOT‐22 scores were ≥ 8.9 compared with baseline, subjects underwent an AECRS assessment. We identified rhinovirus (RV) incidence through viral nasal brushings at each visit and bacterial infection through bacterial swabs if mucus scores were ≥1.ResultsThiry‐five of 80 CRS subjects reported at least one AECRS episode during the year, predominantly occurring in the fall and winter seasons. RV infections were detected in 8 of 35 cases, bacterial infections in 17 of 35, and co‐occurring infections in 7 of 35. All subjects with AECRS visits exhibited significantly higher endoscopic scores compared with baseline. Subjects with co‐occurring RV and bacterial infections demonstrated higher disease severity compared with those with either RV or bacterial infection, or no infection.ConclusionsIn a one‐year prospective longitudinal study involving CRS adults, we identified significant risk factors for AECRS including seasonality and the presence of RV and bacterial infections. These data suggest a standard definition of AECRS and the need to target RV and bacterial infections if we are to help reduce disease severity.