bluuebunny/crossref_metadata_2025_split huggingface dataset:
Las competencias en matemáticas de los estudiantes de grado 5° de educación básica primaria
Authors: Alarcón Piragauta Zulma Paola , Hurtado de Barrera Jacqueline 
Published: September 2024

La presente investigación se desarrolló con el propósito de describir las competencias matemáticas de los estudiantes de grado 5 de educación básica primaria de las sedes del Politécnico Álvaro González Santana, Sogamoso – Boyacá. La investigación se realizó bajo el sintagma de la comprensión holística de la ciencia y el método holopráxico. De acuerdo al nivel de conocimiento, se considera descriptiva, con un diseño de campo, transeccional contemporáneo. La población la conformaron 149 estudiantes de 5° grado de las sedes de la institución, para la recolección los datos se utilizó un cuestionario de medición de competencias matemáticas diseñado con base en las pruebas Saber. El cuestionario constó de 82 ítems y arrojó un puntaje total de 124 puntos, transformado a una escala de 20 puntos para facilitar la interpretación, con una validez de 0,78 y una confiabilidad de Alfa de Cronbach de 0,78. En el análisis de los datos se utilizó la estadística descriptiva, específicamente la medida de tendencia central, la mediana, la frecuencia absoluta y porcentual. Los resultados reflejan que los estudiantes de 5to grado que participaron en el estudio tienen suficientes competencias matemáticas; sin embargo, el nivel de la mediana está en el límite superior de regular y además los componentes cognitivo y procedimental se ubicaron en la categoría de regular, por lo cual se asume que estos estudiantes tienen dificultad en el desarrollo de aspectos teóricos, conceptuales y prácticos en las matemáticas, pero, los resultados del componente actitudinal reflejan que tienen una suficiente disposición hacia su aprendizaje.
Integrative description of a new species of Minibiotus (Tardigrada: Macrobiotidae) from Salta City (Argentina)
Authors: Rocha Alejandra , Doma Irene , Camarda Daniele , Ostertag Belen , Meier Florencia , Frigieri Federica , Cesari Michele , Lisi Oscar 
Published: September 2024

The limno-terrestrial tardigrade fauna of Argentina has been investigated methodically and with modern criteria just in the last two decades, but current knowledge is still incomplete. So far, about 119 limno-terrestrial species are known for the country, of which only 6 belong to the genus Minibiotus R.O. Schuster, 1980. Until 1988, this genus was monotypic, with only Minibiotus intermedius (Plate, 1888), but today the number of species of the genus has risen to 55. In the present contribution, we describe with an integrated approach (PCM, SEM, morphometry and DNA analysis with COI, ITS2, 18S and 28S genes) a new species of Minibiotus from Salta City (Argentina). Minibiotus dispositus sp. nov. has ten transverse bands of variously shaped cuticular pores, arranged in transverse rows, with differences between smaller and larger specimens. Three macroplacoids and a microplacoid are present in the pharynx. The eggs have small conical processes and granulated chorion. The new species is morphologically and morphometrically well differentiated from all other species of the genus, and genetically from the up to date sequenced species. The new species description gave the occasion to broaden knowledge on taxonomy, morphology and faunistics of the genus Minibiotus, and on the tardigrade fauna of Argentina and the Neotropical region.
Penerapan Kaizen Untuk Mempertahankan Pelanggan Pada Masa Pandemi Covid-19 di Perusahaan Jasa Freight Forwarding (Studi Kasus Pada PT. Matrix Logistic Indonesia)
Authors: Akhmad Sopani  
Published: September 2024

Penelitian ini bertujuan untuk mengetahui sejauh mana penerapan Kaizen terhadap kepuasan pelanggan untuk mempertahankan pelanggan pada masa pandemi Covid-19 diperusahaan PT. Matrix Logistic Indonesia. Metode penelitian ini menggunakan lima variabel untuk mewakili kepuasan pelanggan diantaranya adalah Tangible, Empathy, Responsivenes, Realibility dan Assurance. Hasil penelitian menunjukkan bahwa dengan penerapan Kaizen terdapat kenaikan jumlah pelanggan. Dari 6 pelanggan telah mengembalikan umpan balik dan hasil analisis perhitungan bahwa nilai terkecil adalah tangible (bukti fisik) sebanyak 1 pelanggan menyatakan sangat puas, 2 pelanggan menyatakan Puas dan 3 pelanggan menyatakan cukup. Sedangkan untuk 4 variabel lainya Empathy, Responsivenes, Realibility dan Assurance mempunya nilai skor sama 4 pelanggan menyatakan sangat puas dan 2 pelanggan menyatakan puas.
Tomar notas
Authors: Michán Layla 
Published: September 2024

Procesar, comprender, resumir e interpretar la información que se obtiene en una clase, conferencia, seminario o conversación para convertirla en conocimiento, es una estrategia indispensable para la investigación científica, la mejor manera de lograrlo es por medio de la toma de notas en la que se organizan las ideas, los datos y las reflexiones como oraciones breves, que fácilmente se pueden convertir en párrafos estructurados que
السلوك الاستباقي وتأثيره في التحول الرقمي
Authors: الطالب قصي عمر شريف  , الأستاذة الدكتورة جومانة يونس  
Published: September 2024

ان العمل في ظروف البيئة المربكة والمثيرة يحتم على الإدارات البحث عن السبل والاجراءات التي تمكنها من معالجة العواقب السلبية الناتجة عن تاثيرات الظروف المشار اليها ويمكن ان تكون هذه الوسائل علاجية داخلية تتعلق بالأنظمة والقوانين والتكنولوجيا وسلوك العاملين وغيرها.
إذ يعد سلوك العاملين أحد تلك الجوانب المهمة التي نالت عناية كبيرة بسبب تأثيرها القوي على اداء المنظمات ونجاحها لذلك اعتنى الباحثون والكتاب بدراسة سلوك الافراد داخل المنظمات، التي يمكن ان تشكل دراسة أحدالأساليب المهمة في معالجة مشاكل المنظمات اليوم، ومن تلك السلوكيات ما يسمى بالسلوك الاستباقي ( Proactive behavior ) ويتمحور هذا المفهوم حول كيفية تنفيذ الأفراد لمتطلبات وأنشطة العمل بصورة تلقائية و أكثر نجاحاً من دون الحاجة الى توجيه خارجي، ومن السلوكيات التي تندرج تحت هذا المصطلح : اقتراح الأفكار للتحسينات المستقبلية، والوقاية من المشاكل، وتولي المسؤولية، والابتكار الفردي (Belschak & Den Hart,2010 :477)، وعلى الرغم من عمق هذه الظاهرة إلا أن الاستباقية برزت بوصفها موضوعاً رئيسياً من عناية الباحثين والممارسين في السنوات الماضية وبرز الاهتمام بالسلوك الاستباقي بسبب ضعف السلوكيات الرسمية على التنبؤ بالسلوكيات المطلوب أدائها وذلك بسبب ارتفاع عدم التأكد الناتج عن الواقع البيئي الذي تمت الإشارة اليه، وفي هذا المبحث سيتم توضيح عدد من المحاور الخاصة بالسلوك الاستباقي
احكام العبادات
Authors: غزوان عزت سلمان رحيم  , الدكتور هلال درويش  
Published: September 2024

الواجب على المؤمن أن يهتم بعبادته، الحج، والعمرة، والصلاة وغيرها، الواجب عليه أن يهتم بذلك، وأن يعتني وأن يتعلم حتى يؤدي الصلاة على وجهها، ويؤدي الصوم على وجهه، والحج على وجهه، والعمرة على وجهها، يجب أن يتعلم ويتفقه؛ لأن الله أوجب عليه الصلاة، وأوجب عليه صيام رمضان، وأوجب عليه الحج، وأوجب عليه العمرة؛ فلا بد أن يتعلم ما يؤدي به هذا الفرض، ولا يتساهل في هذا، وما لا يتم الواجب إلا به فهو واجب، وقد قال ﷺ: من يرد الله به خيرًا يفقهه في الدين فالتفقه في الدين من علامات أن الله أراد بالعبد خيرًا، والإعراض والغفلة من علامات الشر، ونسأل الله العافية.
العبادة هي إظهار التقدير والاحترام والتكريم والإخلاص. غالبًا ما تتم هذه الممارسة في السياقات الدينية، حيث تشير إلى تقديس عميق لكائن إلهي أو قوة خارقة للطبيعة. ومع ذلك، يمكن للعبادة أن تمتد إلى ما هو أبعد من الأوساط الدينية وتظهر في أشكال مختلفة، بما في ذلك عبادة الأبطال. يشمل نطاق أنشطة العبادة التبجيل أو العشق أو التسبيح أو الدعاء أو الإخلاص أو السجود أو الخضوع. سواء تم إجراؤها من خلال صلاة بسيطة أو حفل مفصل، بشكل فردي أو في إطار جماعي، بشكل غير رسمي أو رسمي، وبقيادة شخصية معينة، فإن الغرض الأساسي من العبادة هو تكريم الموضوع بطريقة ذات معنى.[1]
Perfil epidemiológico da febre amarela no Brasil nos anos de 2018 a 2023
Authors: Barros Araújo João Victor , Duarte Dovera Pablo Diego , Borges Lessa Ana Beatriz , De Moura Batz Guilherme , Maia da Silva Maycon , Bastos de Souza Alana Carolina , De Oliveira Gomes Sales Maria Clara , Xavier Macedo Louise , Prudente Cançado Bárbara , Caruccio Barcelos Cristovão , Maciel Teles Vitor , Lyra Silva Pazione Maria Antonia , Cardoso Batista Santana Beatriz , Martins Batista Victor , Queiroz Santos dos Anjos Guilherme , Rezende Teixeira Diogo , Sousa Aguiar Maria Eduarda 
Published: September 2024

Introdução:A febre amarela é uma doença infecciosa grave causada por um vírus do gênero flavivírus, transmitida pela picada de mosquitos infectados,afetando principalmente regiões tropicais na qual é endêmica.Ademais, é relevante destacar que em 50% dos casos evoluem para o quadros mais graves sucedendo uma alta letalidade.Dessa forma, fica evidente a relevância de entender o perfil epidemiológico da febre amarela.Objetivo:Definir o perfil epidemiológico da no Brasil.Métodos: Trata-se de perfil epidemiológico horizontal retrospectivo que utiliza dados do datasus com o recorte dos anos de 2018 a 2023.Resultado: Foram registradas 1252 internações no período de 2018-2023. Com isso, foram observados mais casos na faixa etária dos 20 a 59 anos, em que foram notificados 879 internações.Discussão: O ano de 2020 teve 48 internações que representa uma queda no número de notificações em relação a 2019 com 91 internações. Ao comparar o período pandêmico com o pós pandêmico foi observado um crescimento seguido de queda no número de notificações. Possivelmente houve uma subnotificação em razão da superlotação de hospitais durante o período pandêmico. Conclusão: Nesse sentido , fica evidente que a superlotação dos hospitais no período pandêmico foi um fator determinante para a diminuição dos casos notificados, bem como as internações pela febre amarela. O presente estudo tem por finalidade inspirar futuras políticas públicas no combate à febre amarela.
Da teoria às boas práticas editoriais
Authors: Santos Gildenir Carolino , Almeida Maria de Lourdes Pinto de , Santos Filho José Camilo dos 
Published: September 2024

Introdução: O movimento de periódicos acadêmicos para a Internet levou a proliferação de novas abordagens para a publicação, onde o modelo de assinatura não é mais predominante; o jogo de interesses praticado para publicar em editoras e associações científicas, agora abre espaço para a publicação gratuita pelas universidades, trazendo economia e aumentando a divulgação da produção científica no ambiente acadêmico. Assim, é primoridia que as publicações sigam as inovações e as boas práticas da editoração científica. Objetivo: Apresentar as boas práticas editoriais utilizadas na RIESUP. Metodologia: A pesquisa é caracterizada com um estudo de caso complementado pela a análise descritiva das boas práticas implantada no fluxo editorial da revista. Resultados: Como resultado, obtivemos os avanços editoriais alcançados pela revista ao longo de quase 10 anos de existência, aprimorando cada vez mais e acompanhando as inovações no campo da editoria científica. Conclusão: Espera-se que a RIESUP possa alcançar cada vez mais a qualidade editorial que almeja com a inclusão nos melhores indexadores mundiais, devido a sua insistência e perseverança na editoração científica.
Inter and Intraserotype Variations of Streptococcus Pneumoniae Pathogenicity in Mice and Rabbits
Authors: J AL-Janabi,AA , IMS Shnawa , AM AL-Sadi 
Published: September 2024

The small mammalian labratory animals, the mice and the rabbits were tempted to be pathogenicity models for S. pneumoniae serotypes 1 and 6, the infecting doses were 0.3ml for mice and 0.5 ml for rabbits. These infectious doses were rated to a count of 1X 10 to 7 CFU/ml. The infection routes were intrapreritoneal for mice and intranasal for rabbits. The gold standard criteria for pathogenicity were the death end point DEP.DEP was up to 24hr for mice and ranged from four to 14 days in rabbits. Mice was more susciptable than rabbits for S. pneumoniae serotypes infections. Autopsy cultures of blood, lungs, liver and kideys were producing same infecting serotype both from mice and rabbits. This isolation profile was indicating bacterimic state induced by infection. Different serotypes have shown different death end points duration time. There were inter and intraserotype variations in DEP. Moderate to severe respiratory disease conditions RDC was noted in mice while mild RDC in rabbits. Both of the tested models were similar lung histology to man. The histological features of this experimental infections have shown that the infected mice and rabbits were of bronchopneumonia type. It appears that both mice and rabbits were standing as valid laboratory animal models for these local clinical isolates of S. pneumoniae serotypes.
Tetraarylethylenes from Diarylmethanones and Hexachlorodisilane: The “Sila‐McMurry” Reaction
Authors: Moxter Maximilian , Tillmann Jan , Füser Matthias , Bolte Michael , Lerner Hans‐Wolfram , Wagner Matthias 
Published: October 2016

AbstractHexachlorodisilane reacts with diarylmethanones (aryl=C6H5, 4‐MeC6H4, 4‐tBuC6H4, 4‐ClC6H4, 4‐BrC6H4) to furnish the corresponding tetraarylethylenes in good yields. The reductive conversion requires temperatures of about 160 °C and reaction times of 60–72 h. In the initial step, the Lewis‐basic carbonyl groups likely generate low‐valent [SiCl2] as an analogue of [TiCl2] in the classical McMurry reaction. The coupling sequence further proceeds via benzopinacolones, which have been isolated as key intermediates.
Impact of a Novel Bioabsorbable Implant on Radiation Treatment Planning for Breast Cancer
Authors: Cross Michael J. , Lebovic Gail S. , Ross Joseph , Jones Scott , Smith Arnold , Harms Steven 
Published: October 2016

AbstractBackgroundTechniques for accurately delineating the tumor bed after breast‐conserving surgery (BCS) can be challenging. As a result, the accuracy, and efficiency of radiation treatment (RT) planning can be negatively impacted. Surgically placed clips or the post‐surgical seroma are commonly used to determine target volume; however, these methods can lead to a high degree of uncertainty and variability. A novel 3‐dimensional bioabsorbable marker was used during BCS and assessed for its impact on RT planning.MethodsOne hundred and ten implants were sutured to the margins of the tumor bed excision site in 108 patients undergoing BCS. Routine CT imaging of the breast tissue was performed for RT planning, and the marker was assessed for visibility and utility in target delineation. RT regimens, target volumes and associated treatment costs were analyzed.ResultsIn all patients, the marker was easily visible and in 95.7 % of cases, it proved useful for RT planning. 36.8 % of patients received conventional whole breast irradiation plus boost, 56.6 % received hypo‐fractionation plus boost, and 6.6 % received accelerated partial breast irradiation. A shift toward increased use of hypo‐fractionated regimens was noted over the three year period of this study. There were no device‐related complications or cancer recurrences in this group of patients.ConclusionsThis study demonstrated the use of a novel 3‐dimensional marker as a safe and effective method for delineating the tumor bed with a significant utility for RT planning. With routine use of the device, an increased use of hypofractionation with a resultant 25 % cost savings was noted.
OPTIMAL FINANCING AND DIVIDEND DISTRIBUTION WITH TRANSACTION COSTS IN THE CASE OF RESTRICTED DIVIDEND RATES
Authors: Zhu Jinxia 
Published: October 2016

AbstractWe consider the optimal financing (capital injections) and dividend payment problem for a Brownian motion model in the case of restricted dividend rates. The company has no obligation to inject capitals and therefore, the bankruptcy risk is present. Capital injections, if any, will incur both fixed and proportional transaction costs and dividend payments incur proportional transaction costs. The aim is to find the optimal strategy to maximize the expected present value of dividend payments minus the total cost of capital injections up to the time of bankruptcy. The problem is formulated as a mixed impulse-regular control problem. We address the problem via studying three cases of two auxiliary functions. We derive important analytical properties of the auxiliary functions and use them to study the value function and then identify the optimal control strategy. We show that the optimal dividend control is of threshold type and the optimal financing strategy prescribes to either never inject capitals or inject capitals only when the surplus reaches 0 with a fixed lump sum amount.
Nutrition education linked to agricultural interventions improved child dietary diversity in rural Cambodia
Authors: Reinbott Anika , Schelling Anna , Kuchenbecker Judith , Jeremias Theresa , Russell Iean , Kevanna Ou , Krawinkel Michael B. , Jordan Irmgard 
Published: October 2016

AbstractPoor infant and young child feeding (IYCF) practices are major determinants of chronic malnutrition. The main objective of this study was to assess the impact of a nutrition education (NE) programme aimed at promoting improved IYCF behaviours in combination with an agriculture intervention on children’s dietary diversity and nutritional status. From 2012 to 2014, a cluster randomised trial was rolled out in Cambodia in the context of an agriculture and nutrition project of the FAO of the UN. The cross-sectional baseline study was carried out in sixteen pre-selected communes in 2012. Restricted randomisation allotted the communes to either intervention (NE and agriculture intervention) or comparison arms (agriculture intervention only). The impact survey was conducted as a census in all FAO project villages in 2014. Caregivers of children aged 0–23 months were interviewed using standardised questions on socio-economic status and dietary diversity (24-h recall). Anthropometric measurements were taken. A difference-in-differences model was applied. The sample comprised 743 households with children ≥6 months of age at baseline and 921 at impact. After 1 year of NE, 69 % of the intervention households reported to have participated in the NE. Estimated mean child dietary diversity was significantly different at impact between comparison and intervention (3·6 and 3·9, respectively). In particular, the consumption of pro-vitamin A-rich foods and other fruits and vegetables increased. No treatment effects on height-for-age Z-scores could be shown. NE led to improvements in children’s diets. For effects on growth, it is assumed that longer NE activities are required to achieve sustainable behaviour change of age-appropriate infant feeding.
Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor
Authors: Ramkumar Kavya , Samanta Soma , Kyani Anahita , Yang Suhui , Tamura Shuzo , Ziemke Elizabeth , Stuckey Jeanne A. , Li Si , Chinnaswamy Krishnapriya , Otake Hiroyuki , Debnath Bikash , Yarovenko Vladimir , Sebolt-Leopold Judith S. , Ljungman Mats , Neamati Nouri 
Published: October 2016

AbstractGlutathione S-transferase omega 1 (GSTO1) is an atypical GST isoform that is overexpressed in several cancers and has been implicated in drug resistance. Currently, no small-molecule drug targeting GSTO1 is under clinical development. Here we show that silencing of GSTO1 with siRNA significantly impairs cancer cell viability, validating GSTO1 as a potential new target in oncology. We report on the development and characterization of a series of chloroacetamide-containing potent GSTO1 inhibitors. Co-crystal structures of GSTO1 with our inhibitors demonstrate covalent binding to the active site cysteine. These potent GSTO1 inhibitors suppress cancer cell growth, enhance the cytotoxic effects of cisplatin and inhibit tumour growth in colon cancer models as single agent. Bru-seq-based transcription profiling unravelled novel roles for GSTO1 in cholesterol metabolism, oxidative and endoplasmic stress responses, cytoskeleton and cell migration. Our findings demonstrate the therapeutic utility of GSTO1 inhibitors as anticancer agents and identify the novel cellular pathways under GSTO1 regulation in colorectal cancer.
Large linear magnetoresistance in heavily-doped Nb:SrTiO3 epitaxial thin films
Authors: Jin Hyunwoo , Lee Keundong , Baek Seung-Hyub , Kim Jin-Sang , Cheong Byung-ki , Park Bae Ho , Yoon Sungwon , Suh B. J. , Kim Changyoung , Seo S. S. A. , Lee Suyoun 
Published: October 2016

AbstractInteraction between electrons has long been a focused topic in condensed-matter physics since it has led to the discoveries of astonishing phenomena, for example, high-Tc superconductivity and colossal magnetoresistance (CMR) in strongly-correlated materials. In the study of strongly-correlated perovskite oxides, Nb-doped SrTiO3 (Nb:SrTiO3) has been a workhorse not only as a conducting substrate, but also as a host possessing high carrier mobility. In this work, we report the observations of large linear magnetoresistance (LMR) and the metal-to-insulator transition (MIT) induced by magnetic field in heavily-doped Nb:STO (SrNb0.2Ti0.8O3) epitaxial thin films. These phenomena are associated with the interplay between the large classical MR due to high carrier mobility and the electronic localization effect due to strong spin-orbit coupling, implying that heavily Nb-doped Sr(Nb0.2Ti0.8)O3 is promising for the application in spintronic devices.
Matrix factorization reveals aging-specific co-expression gene modules in the fat and muscle tissues in nonhuman primates
Authors: Wang Yongcui , Zhao Weiling , Zhou Xiaobo 
Published: October 2016

AbstractAccurate identification of coherent transcriptional modules (subnetworks) in adipose and muscle tissues is important for revealing the related mechanisms and co-regulated pathways involved in the development of aging-related diseases. Here, we proposed a systematically computational approach, called ICEGM, to Identify the Co-Expression Gene Modules through a novel mathematical framework of Higher-Order Generalized Singular Value Decomposition (HO-GSVD). ICEGM was applied on the adipose and heart and skeletal muscle tissues in old and young female African green vervet monkeys. The genes associated with the development of inflammation, cardiovascular and skeletal disorder diseases and cancer were revealed by the ICEGM. Meanwhile, genes in the ICEGM modules were also enriched in the adipocytes, smooth muscle cells, cardiac myocytes and immune cells. Comprehensive disease annotation and canonical pathway analysis indicated that immune cells, adipocytes, cardiomyocytes and smooth muscle cells played a synergistic role in cardiac and physical functions in the aged monkeys by regulation of the biological processes associated with metabolism, inflammation and atherosclerosis. In conclusion, the ICEGM provides an efficiently systematic framework for decoding the co-expression gene modules in multiple tissues. Analysis of genes in the ICEGM module yielded important insights on the cooperative role of multiple tissues in the development of diseases.
New low-flux mixed matrix membranes that offer superior removal of protein-bound toxins from human plasma
Authors: Pavlenko Denys , van Geffen Esmée , van Steenbergen Mies J. , Glorieux Griet , Vanholder Raymond , Gerritsen Karin G. F. , Stamatialis Dimitrios 
Published: October 2016

AbstractHemodialysis is a widely available and well-established treatment for patients with End Stage Renal Disease (ESRD). However, although life-sustaining, patient mortality rates are very high. Several recent studies corroborated the link between dialysis patients’ outcomes and elevated levels of protein-bound uremic toxins (PBUT) that are poorly removed by conventional hemodialysis. Therefore, new treatments are needed to improve their removal. Recently, our group showed that the combination of dialysis and adsorption on one membrane, the mixed matrix membrane (MMM), can effectively remove those toxins from human plasma. However, these first MMMs were rather large in diameter and their mass transport characteristics needed improvement before application in the clinical setting. Therefore, in this study we developed a new generation of MMMs that have a smaller diameter and optimized characteristics offering superior ability in removing the PBUT indoxyl sulfate (IS) and p-cresyl sulfate (pCS) in comparison to first generation MMMs (30 and 125% respectively), as well as, a commercial dialysis membrane (more than 100% better removal).