bluuebunny/crossref_metadata_2025_split huggingface dataset:
Project approach and Scrum principles as tools for flexible formation of IT specialists’ competencies
Authors: Lunina Yu. V. , Smirnova G. S. , Sabitov R. A. 
Published: February 2025

The demand for training IT specialists with both fundamental knowledge and professional competencies that meet the current requirements of employers sets conditions for the search for relevant training methods. The article discusses an experiment to introduce the project approach using one of the tools of agile project development methodology (Scrum) in the process of training IT specialists through cooperation of a university and an IT company. Within the framework of the project “Digital Department” students were retrained and received a new qualification “Information Systems Specialist”. The authors describe the advantages of the educational model used, which combines the mastering of theoretical knowledge with the solution of real practical cases in the format of team projects. The following aspects of the educational process organization are noted: the choice of the optimal type of training, the balance between the acquisition of new knowledge and the development of practical skills, the definition of the roles of teachers and students, as well as the creation of an engaging educational environment.The article describes the structure and course of students’ work on projects using the Scrum methodology. The analysis of the experiment results and evaluation of its effectiveness in the formation of demanded competencies of graduates are given. It is noted that students’ involvement in project activities provides a high degree of motivation and success: the main dropout of the experiment participants occurred at the theoretical stage of preparation for the project, and students who reached the stage of project activities successfully implemented their projects. Thus, the introduction of the project approach and Scrum methodology in the educational process contributes to the improvement of the quality of education and training of qualified specialists ready for the challenges of the modern labor market.The results of the experiment described in the article can serve as a basis for further research and development of recommendations for optimization of educational programs.
Structural mental approach to learning questions design
Authors: Barkhatova D. A. , Pak N. I. 
Published: February 2025

In the context of the global information boom, the question-and-answer form of teaching is the most preferable and effective for the digital generation, as it is oriented to maximize the activation of learners’ thought processes. Despite the fact that question-answer teaching is not new in pedagogy, practice shows the low readiness of teachers to design learning questions. The article is devoted to clarifying and describing the approach to constructing learning questions. In practice, this approach would allow the teacher to competently formulate learning questions to achieve better educational results, and students not only to search for answers to them, but also to learn how to compose questions themselves.The main idea of the approach to constructing learning questions is information modeling of objects and concepts of the subject area. The methodology of designing learning questions supposes the decomposition of the information model of educational material in accordance with its structure, presentation features, and educational effect. Educational material is usually classified by educational functions: theory, practice, control. Accordingly, three algorithms for composing questions are identified: on theoretical material, on practical material, and questions on understanding, which are control and measuring tools.The proposed approach to constructing learning questions for various types of educational material may be of interest to teachers, students of pedagogical universities, as well as students of psychological and pedagogical classes. The approach will also be useful for developers of electronic educational resources. Further research in this direction is planned to be expanded to the creation of a theory of learning questions from the perspective of the digital transformation of education.
Geoquímica y espeleogénesis de cuevas de cuarzoarenita en la serranía de Chiribiquete, sector de los ríos Caquetá y Yarí, Colombia
Authors: Sauro Francesco , Lasso Carlos A. 
Published: February 2025

El área objetivo de esta investigación fue el territorio del Resguardo Indígena Monochoa, al sur de los límites del Parque Nacional Chiribiquete, una zona del macizo de cuarzoarenitas (Formación Araracuara), atravesada por los ríos Caquetá y Yarí, Amazonia (Colombia). La primera expedición (febrero de 2022) estudió la Cueva de Los Guácharos, una resurgencia que se abre en la margen izquierda del cañón del río Caquetá (Araracuara). En febrero de 2023, una expedición científica formada por indígenas Uitoto y Andoque y espeleólogos colombianos, italianos y franceses remontó el río Yarí hasta los rápidos de Gamitana, llegando a los tepuyes del Yarí. Se hizo la exploración y topografía de dos grandes cuevas horizontales. La primera resultó ser un gran túnel de unos 600 m de longitud total. La segunda corresponde a la base de una gran sima, que da acceso a un túnel horizontal activo; se levantó la topografía a lo largo de unos 400 metros hacia el exterior de la resurgencia en la base de la montaña, tras una distancia de casi un kilómetro. Además de las exploraciones, se llevaron a cabo varias investigaciones científicas sobre la hidroquímica, bioespeleología y geología de la zona, petrografía de las cuarzoarenita y los extraordinarios espeleotemas de ópalo, similares a los ya descubiertos en Venezuela. Los datos preliminares muestran que la espeleogénesis se produce por procesos de disolución intergranular del cuarzo, que conducen a la “arenización” y posterior erosión acelerada de capas específicas. La presencia de una capa de “Banded Iron Formation” favorece la formación de cuevas en un intervalo estratigráfico específico.
Introducing Research into Pactice: Establishing the Evidence-based Moving on Programme as Part of Standardized Cancer Care
Authors: Richmond Janice , Toby Teraze , Kerr Tommy , Hobbins Anna , Gillespie Paddy , Kelly Mary grace 
Published: February 2025

The Moving On Programme (MOP) was developed as a specific intervention to fill an identified service need. This programme was piloted and analyzed by previous research and this paper outlines the process and challenges of introducing the MOP to become part of standardized cancer care. Any adaptations that were required due to the global COVID-19 pandemic restrictions are outlined. Health economic analysis outlines the cost of the MOP and participants’ evaluations are presented. MOP has the potential to be far reaching in its appeal and could easily be transferred to other regions.
Famílias que integram pessoas dependentes no autocuidado e os recursos utilizados pelas famílias e enfermagem de reabilitação
Authors: Mendes João Pedro , Loureiro Maria , Cardoso Cátia , Caridade Joana , Mariz Manuel , Bento Maria da Conceição 
Published: February 2025

Introdução: A evolução demográfica em Portugal é caracterizada por um envelhecimento populacional marcado, com elevados índices de dependência associados, representando um enorme desafio para famílias que integram pessoas dependentes, no domicílio. Torna-se importante, identificar os recursos e produtos de apoio facilitadores do autocuidado utilizados pelas famílias que cuidam destas pessoas.
Metodologia: Estudo exploratório, descritivo, transversal e de cariz quantitativo, amostra probabilística, aleatória. O instrumento de colheita de dados utilizado foi utilizado o formulário “Famílias que integram dependentes no autocuidado”.
Resultados: Foram incluídas 35 famílias que integravam pessoas dependentes no autocuidado. O número de pessoas dependentes foi de 37, 54,1% do género feminino, viúvas e com idade média de 83,1 anos (±9,9 anos). A dependência foi de instalação gradual (73%) devido ao envelhecimento e doenças crónicas e durava, há cerca de 4,2(±4,8) anos. Os cuidadores eram 80% do género feminino, casados, filhos da pessoa dependente e idade média de 65,6 anos (±10,1 anos). A taxa global de recursos utilizados foi de 50,4%, com maior expressão nos autocuidados de tomar medicação, andar e uso do sanitário (média-73,8%), e os de menor utilização relacionados à mobilidade: elevar-se, virar-se e transferir-se (média - 25.1%).
Discussão: Existe uma subutilização dos recursos/produtos de apoio por parte das famílias que é condizente com a literatura. O estudo alerta também, para maior valorização de autocuidados relacionados com aspetos vitais e de sobrevivência. As famílias indicam a falta de conhecimentos sobre o seu funcionamento como causa para não utilizarem, demonstrando a importância da literacia.
Conclusão: O EEER é fundamental na capacitação do cuidador para a seleção e utilização dos recursos/produtos de apoio adequados, devendo esta prática ser disseminada.
Peran Sekuritisasi Sebagai Pendanaan Ekspansi Kredit Pemilikan Rumah Pada Bank BTN
Authors: Maulana Dede Hikmat , Gursida Hari , Indrayono Yohanes 
Published: February 2025

Banks as intermediary institutions collect funds from the public in the form of and provide credit, one of which is Home Ownership Credit/KPR. However, there is a risk of a mismatch between funding and bank financing. KPR credit which has a long term is not comparable to funding sources from bank customer deposits which have a tenor of less than 1 year. Bank BTN as a bank that focuses on housing financing continues to pursue mortgage credit growth, one of which is by means of mortgage securitization. KPR securitization as a relatively cheap source of long-term funding is one of Bank BTN's ways of expanding KPR credit. The aim of this research is to determine the impact of securitization on the financial performance and company performance of Bank BTN. This research is expected to provide an understanding regarding KPR securitization and the development of KPR credit in Indonesia, especially KPR securitization carried out by Bank BTN in the period 2018 to 2023. The analytical method used in this research is qualitative descriptive analysis. The data used in this research uses secondary data sources, including publications of company financial reports, government policies and regulator reports. Data collection techniques in this research used documentation, observation and interview techniques. The research results show that although KPR securitization has a positive impact on Bank BTN's liquidity and is used as an alternative source of financing for KPR expansion, it does not have a significant impact on shareholder profits.
Pengaruh Financial Technology, Literasi Keuangan, Inklusi Keuangan, Aksesibilitas Kredit Terhadap Keberlangsungan UMKM
Authors: Asmoro Wiwiek Kusumaning , Setiawan Mohamad Arief , Setianingsih Novie Astuti , Putranti Eti 
Published: February 2025

Rapid technological developments have made changes in various sectors one of them is the financial sector. Financial technology, Financial Inclusion, Financial Literacy and Credit Accessibility as One form of development in the financial sector. This study aims to determine the influence of Financial Technology, Financial Literacy, Financial Inclusion and Credit Accessibility on the Sustainability of MSMEs in Kediri City. This research data is primary data collected through a questionnaire using a technique with a purposive sampling approach. The population of 517 MSME actors in the Culinary Sector with the calculation of the sample of the slovin formula of respondents from MSMEs in Kediri City was 84 samples. The data was obtained from a questionnaire distributed to MSME owners in the Culinary Sector registered at the Kediri City Cooperative and SME Trade Office. This study uses multiple linear regression analysis with the application of SPSS 23. The results of the study show that financial technology. Financial literacy, financial inclusion and credit accessibility have a positive and significant effect on the sustainability of MSMEs. Therefore, it can be concluded that the importance of financial technology for MSMEs in developing their business as well as financial literacy, financial inclusion and credit accessibility will have an impact on MSME capital and business sustainability.
Post-Election Reconciliation in 2024 as a Constitutional Convention in Indonesia: A Progressive Legal Culture Perspective
Authors: Prasetio Dicky Eko , Masnun Muh. Ali , Noviyanti Noviyanti 
Published: February 2025

Post-general election reconciliation takes place to prevent polarisation and ongoing conflict after the general election in Indonesia. This research analyses and formulates post-2024 election reconciliation as a constitutional convention that must be implemented to maintain national unity and support progressive legal culture practices. The progressive legal culture refers to the character and culture of Indonesian society, emphasising the family dimension and noble values in society. This research is normative legal research, prioritising conceptual and statutory approaches. The research results confirm that constitutional conventions, as unwritten laws that must be obeyed, should fulfil several characteristics: repeated constitutional acts, substantially based on political ethics and constitutional morality, and having ethical binding force.Â When recognised as a constitutional convention, post-election reconciliation should serve as a moral and ethical framework that guides political actors and society in maintaining unity. The implication of post-election reconciliation as a constitutional convention is that it has ethical validity and must be implemented; however, if such reconciliation is not observed, it cannot be fair for the judicial institution. This research recommends the institutionalisation of post-election reconciliation as a constitutional convention, ensuring that Indonesiaâ€™s legal culture prioritises morality and minimises societal divisions, safeguarding national unity and preventing social disintegration.
Facing Digital Age: Should the Regional Regulation Be Made Digitally?
Authors: Fatkhurohman Fatkhurohman , Sirajuddin Sirajuddin , Al Fatih Sholahudin 
Published: February 2025

In forming a Regional Regulation, the Regent must interact formally with the Governor and the Ministry of Law and Human Rights through a facilitation and consultation evaluation mechanism. Providing recommendations for assessing draft regional regulations can confuse those proposing them because suggestions for improvements between the Governor and the Ministry of Law and Human Rights are not well coordinated and are carried out manually. This research aims to find a solution by optimizing coordination methods with digital application networks, especially in establishing regional regulations so that they occur quickly and accurately. This research will later be carried out using an empirical juridical approach, where researchers will delve more into primary data by discovering countless realities in the field regarding the effectiveness and efficiency of the implementation of evaluations by the Governor and the Ministry of Law and Human Rights during the implementation of the assessment of draft regional regulations. This research shows that coordination between the Governor and the Ministry of Law and Human Rights needs to be carried out jointly based on an agreement in evaluating regional regulation proposals so that assessments are distinct. To makeÂ this process runeffectively and efficiently, it is better to do it online via a digital application.
Profiling of the gut, skin and nasal microbiotas revealed clinically relevant microbial taxa from children with allergies: a pilot study
Authors: Hong Jiayi , Tang Zhiwei , Zhang Dongjun , Mo Chenqi , Su Wen , Shao Jie 
Published: February 2025

BackgroundA reduction in biodiversity and alterations in the microbiota composition are relevant to allergic diseases. However, combined analyses of the skin, nasal and gut microbiotas are lacking in the literature. In addition, in previous studies, microbiota were detected mainly by V3–V4 sequencing, but other sequences might be missed with this technique.MethodsIn this case–control study, we enrolled 3–12-year-old children with allergic rhinitis combined with atopic dermatitis and food allergy (AR-AD-FA group), children with allergic rhinitis only (AR-only) and healthy controls (HC group). We employed full-length 16S rRNA gene amplification and sequencing for the detection of gut, nasal and skin microbiota.ResultsSamples with an average sequence length of 1,459 bp were obtained in this study. Significant differences in beta diversity in the three compartments were found between the disease groups and the HC group. Differentially expressed genera were present mainly in the gut compartment. Peptoniphilus, Prevotella and Anaerococcus were abundant in the gut in the disease groups. Specifically, Streptomyces, Thermus and Pseudomonas showed differential expression in both the nasal and skin compartments of children in the disease groups.ConclusionSome meaningful differences in the abundance of some microbiota from the three compartments were observed between the disease groups and the HC group. These findings could provide new insights into the prevention and treatment of allergic diseases through the regulation of specific microbiota in the future.
Myocardial dysfunction caused by MyBPC3 P459fs mutation in hypertrophic cardiomyopathy: evidence from multi-omics approaches and super-resolution imaging
Authors: Wu Yupeng , Zhang Yuzhu , Zheng Qirui , Wang Qiyuan , Fang Xingyu , Zhu Zaihan , Lu Jing , Sun Dandan 
Published: February 2025

IntroductionMutations in the sarcomere protein, particularly in cardiac myosin binding protein C gene (MyBPC3), were the most frequent genetic cause of hypertrophic cardiomyopathy (HCM). The pathogenic MyBPC3 P459fs mutation has been reported in HCM patients. However, there was limited knowledge of the structure–function relationships and potential pathways in clinical HCM with MyBPC3 P459fs mutation.MethodsWe used multi-omics approaches and super-resolution imaging to explore the effects of MyBPC3 P459fs mutation on humans and cells. HCM patients carrying MyBPC3 P459fs mutation (MyBPC3-P459fs HCMs) and healthy controls (HCs) were evaluated for myocardial function using both conventional and advanced echocardiography. In parallel, H9C2 myocardial cells infected with either MyBPC3 P459fs mutation (P459fs cells) or its wild type (WT cells) were investigated for myocardial fiber formation and the potential pathways behind this using super-resolution imaging and metabolomics and proteomics.ResultsFirst, conventional and advanced echocardiography showed that MyBPC3-P459fs HCMs exhibited left ventricular diastolic and systolic dysfunction. Subsequently, super-resolution imaging indicated that P459fs cells formed fewer and shorter myocardial fibers in the cytoplasm compared to WT cells. Moreover, our metabolomic and proteomic data suggested several key components of mitochondrial membrane integrity, myocardial remodeling, myocardial energy metabolism, oxidative stress, inflammation, and actin binding capacity were significantly altered in response to P459fs mutation.ConclusionsThis investigation indicated myocardial dysfunction and myocardial fiber disarray in clinical HCMs with MyBPC3 P459fs mutation and added potential pathways underlying this. These findings provided a link between the observed structural and functional disorders in MyBPC3 P459fs mutation and its onset of HCM pathogenesis and might have a significant translational contribution to effective treatment in HCM patients with MyBPC3 P459fs mutation.
Development and validation of a risk prediction model for 30-day readmission in elderly type 2 diabetes patients complicated with heart failure: a multicenter, retrospective study
Authors: He Yuxin , Yuan Yuan , Tan Qingzhu , Zhang Xiao , Liu Yunyu , Xiao Minglun 
Published: February 2025

BackgroundElderly type 2 diabetes mellitus (T2DM) patients complicated with heart failure (HF) exhibit a high rate of 30-day readmission. Predictive models have been suggested as tools for identifying high-risk patients. Thus, we aimed to develop and validate a predictive model using multicenter electronic medical records (EMRs) data to estimate the risk of 30-day readmission in elderly T2DM patients complicated with HF.MethodsEMRs data of elderly T2DM patients complicated with HF from five tertiary hospitals, spanning 2012 to 2023, were utilized to develop and validate the 30-day readmission model. The model were evaluated using holdout data with the area under the receiver operating characteristic curve (AUROC), calibration curves, decision curve analysis (DCA), and clinical impact curves (CIC).ResultsA total of 1899 patients were included, with 955, 409, and 535 in the derivation, internal validation, and external validation cohorts, respectively. Pulmonary infections (odds ratio [OR]: 3.816, 95% confidence interval [CI]: 2.377-6.128, P &lt; 0.001), anti-hypertensive drug use (OR: 5.536, 95% CI: 1.658-18.486, P = 0.005), and neutrophil percentage-to-albumin ratio (NPAR) (OR: 1.144, 95% CI: 1.093-1.197, P &lt; 0.001) were independent predictors of 30-day readmission risk. AUROC in the derivation, internal validation, and external validation cohorts were 0.782 (95% CI: 0.737-0.826), 0.746 (95% CI: 0.654-0.838), and 0.753 (95% CI: 0.684-0.813), respectively. The calibration curve, DCA results, and CIC results indicated that the model also possessed good predictive power. Additionally, an operation interface on a web page (https://cqykdxtjt.shinyapps.io/readmission/) was created for clinical practitioners to apply.ConclusionA 30-day readmission risk prediction model was developed and externally validated. This model facilitates the targeting of interventions for elderly T2DM patients complicated with HF who are at high risk of an early readmission.
Machine learning-driven ultrasound radiomics for assessing axillary lymph node burden in breast cancer
Authors: Wang Si-Rui , Tian Feng , Zhu Tong , Cao Chun-Li , Wang Jin-Li , Li Wen-Xiao , Li Jun , Hou Ji-Xue 
Published: February 2025

ObjectiveThis study explores the value of combining intratumoral and peritumoral radiomics features from ultrasound imaging with clinical characteristics to assess axillary lymph node burden in breast cancer patients.MethodsA total of 131 breast cancer patients with axillary lymph node metastasis (ALNM) were enrolled between June 2019 and September 2024. Patients were divided into low (n=79) and high (n=52) axillary lymph node burden (ALNB) groups. They were further split into training (n=92) and validation (n=39) cohorts. Intratumoral and peritumoral features were analyzed using the maximum relevance minimum redundancy (MRMR) and least absolute shrinkage and selection operator (LASSO) methods. Six machine learning models were evaluated, and a combined clinical-radiomics model was built.ResultsThe combined logistic regression model exhibited superior diagnostic performance for high axillary lymph node burden, with areas under the ROC curve (AUC) of 0.857 in the training cohort and 0.820 in the validation cohort, outperforming individual models. The model balanced sensitivity and specificity well at a 52% cutoff value. A nomogram provided a practical risk assessment tool for clinicians.ConclusionThe combined clinical-radiomics model showed excellent predictive ability and may aid in optimizing management and treatment decisions for breast cancer patients.