bluuebunny/crossref_metadata_2025_split huggingface dataset:
Local stakeholder judgements of the social acceptability of applying environmental water in the Gunbower Island forest on the Murray River, Australia
Authors: Mendham Emily , Curtis Allan 
Published: January 2018

Abstract
Australian governments have purchased large volumes of water from irrigators to decrease the amount of water diverted for agriculture to improve the health of the Murray River. Irrigation entitlements ‘bought back’ are managed by government agencies and are broadly described as ‘environmental water’. The water reform process, the volume of water bought back from irrigators and the objectives and application of environmental water are all contested by irrigators and local communities. This paper provides the first examination of the social acceptability of environmental water in Australia with a case study of Gunbower Island on the Murray River using a survey of local stakeholders. Most respondents visited Gunbower Island regularly, placed a high value on the island and were committed to maintaining the health of the island. Nevertheless, respondents were more likely to exhibit unfavourable judgements about environmental water. Positive judgements were associated with pro-environmental values, belief in the benefits of environmental water and higher levels of trust in the managing agency. Findings provide insights about how the key agency can improve the social acceptability of environmental water in Gunbower Island, including a greater focus on on-ground work as an opportunity to engage local people in learning and action.
Repurposing N,N-Dimethylacetamide (DMA), a Pharmaceutical Excipient, as a Prototype Novel Anti-inflammatory Agent for the Prevention and/or Treatment of Preterm Birth
Authors: Gorasiya Samir , Mushi Juliet , Pekson Ryan , Yoganathan Sabesan , Reznik Sandra E. 
Published: January 2018

Background:
Preterm birth (PTB), or birth that occurs before 37 weeks of gestation, accounts for the
majority of perinatal morbidity and mortality. As of 2016, PTB has an occurrence rate of 9.6% in the United
States and accounts for up to 18 percent of births worldwide. Inflammation has been identified as the most common
cause of PTB, but effective pharmacotherapy has yet to be developed to prevent inflammation driven PTB.
Our group has discovered that N,N-dimethylacetamide (DMA), a readily available solvent commonly used as a
pharmaceutical excipient, rescues lipopolysaccharide (LPS)-induced timed pregnant mice from PTB.

Methods:
We have used in vivo, ex vivo and in vitro approaches to investigate this compound further.

Results:
Interestingly, we found that DMA suppresses cytokine secretion by inhibiting nuclear factor-kappa B
(NF-κB). In ongoing work in this exciting line of investigation, we are currently investigating structural analogs
of DMA, some of them novel, to optimize this approach focused on the inflammation associated with PTB.

Conclusion:
Successful development of pharmacotherapy for the prevention of PTB rests upon the pursuit of
multiple strategies to solve this important clinical challenge.
Recombinant Protein Expression in Escherichia coli (E.coli): What We Need to Know
Authors: Hayat Seyed Mohammad Gheibi , Farahani Najmeh , Golichenari Behrouz , Sahebkar Amirhossein 
Published: January 2018

Background:
Host, vector, and culture conditions (including cultivation media) are considered among
the three main elements contributing to a successful production of recombinant proteins. Accordingly, one of the
most common hosts to produce recombinant therapeutic proteins is Escherichia coli.

Methodology:
A comprehensive literature review was performed to identify important factors affecting production
of recombinant proteins in Escherichia coli.

Results:
Escherichia coli is taken into account as the easiest, quickest, and cheapest host with a fully known
genome. Thus, numerous modifications have been carried out on Escherichia coli to optimize it as a good candidate
for protein expression and; as a result, several engineered strains of Escherichia coli have been designed. In
general; host strain, vector, and cultivation parameters are recognized as crucial ones determining success of
recombinant protein expression in Escherichia coli. In this review, the role of host, vector, and culture conditions
along with current pros and cons of different types of these factors leading to success of recombinant protein
expression in Escherichia coli were discussed.

Conclusion:
Successful protein expression in Escherichia coli necessitates a broad knowledge about physicochemical
properties of recombinant proteins, selection among common strains of Escherichia coli and vectors, as
well as factors related to media including time, temperature, and inducer.
Investigating the Therapeutic Effects of Alginate Nanogel Co-loaded with Gold Nanoparticles and Cisplatin on U87-MG Human Glioblastoma Cells
Authors: Neshastehriz Ali , Khateri Maziar , Ghaznavi Habib , Shakeri-Zadeh Ali 
Published: January 2018

Background and Purpose: It has been well-known both gold nanoparticles (AuNPs) and cisplatin are
potential radiosensitizers for radiotherapy of cancer. In this in vitro study, we investigated the chemoradiotherapeutic
effects of alginate nanogel co-loaded with AuNPs and cisplatin (ACA) on U87-MG human
glioblastoma cells.

Methods:
Based on the accomplished pilot studies, U87-MG cells were incubated with ACA and cisplatin at
10% inhibitory concentration (IC10) for 4h. Then, the cells were irradiated to different doses of 6MV X-rays (2
and 10 Gy). MTT assay was performed to evaluate the cell survival rate. Apoptosis was determined by flow
cytometry using an annexinV–fluorescein isothiocyanate/propidium iodide apoptosis detection kit.

Results:
The results showed that ACA at the concentration of 4 µg/ml (per cisplatin) and free cisplatin at concentration
of 15 μg/ml have the same effects on U87-MG cells (survival rate: 90%). The combination of ACA
with radiation resulted in a significant decrease in cell viability (survival rate: 30%). The flow cytometry assay
also showed that such a combination therapy induces more apoptosis than necrosis.

Conclusion:
It may be concluded that co-delivery of AuNPs and cisplatin with a single nanoplatform like ACA
nanocomplex enhances the therapeutic ratio of human glioblastoma radiation therapy.
Attitudes of Jordanian Adolescent Students Toward Overweight and Obesity
Authors: Abu Baker Nesrin N. , Al-Ali Nahla , Al-Ajlouni Ranyah 
Published: January 2018

Background:
Obesity is a serious public health problem especially among adolescents. Understanding adolescents’ attitudes toward obesity and healthy lifestyle is a crucial step to develop effective health programs to treat and prevent obesity.

Objectives:
To examine the attitudes toward overweight and obesity among Jordanian adolescent students and to identify the components of obesity prevention program that the students perceive as important.

Methods:
A sample of 1000 students in 8th to 10th grades was randomly selected from 16 schools in Irbid, Jordan. A self-reported questionnaire including attitude related questions was used in a descriptive, cross-sectional study.

Results:
Generally, the students expressed positive attitudes toward obesity; which means that their attitudes were consistent with societal norms in terms of health and social functioning (mean= 3.5, SD=0.39). Furthermore, the students expressed positive attitudes toward lifestyle; which means that their attitudes were consistent with healthy behaviors (mean=3.7, SD=0.58). However, boys had significantly more positive attitudes than girls (p=0.04). The prevalence of overweight and obesity was 23.8%, while obese and non-obese students had similar attitudes toward lifestyle and obesity. Finally, around 20% to 30% of students desired a prevention program out of school time shared with their families and friends and involves eating healthy food and getting more exercise.

Conclusion:
More efforts are needed to build effective obesity prevention programs that focus on eating healthy diet and getting more exercise considering gender differences.
Ethnomedicinal studies of some tree species of Chamba district (Himachal Pradesh) India.
Authors: Arora Asha , Sharma Mukesh , Gupta Sushma 
Published: January 2018

The present study encompasses 121 ethno-medicinal uses of 26 tree species of 20 families deployed for 75 maladies and 16 body systems as included in WHO-ICD 11 by Gaddi and Gurjar tribes of Chamba region (Himachal Pradesh). Tribal’s were more familiar to therapeutic plants used for digestive disorders i.e. 24 use reports of 16 tree species followed by skin maladies and localized infections. No citation regarding immune system, circulatory, sensory systems, mental, behavioral / neuro-developmental disorders, sleep-wake disorders, conditions related to sexual health and injury, poisoning or certain other consequences of external causes was obtained. Taxus baccata was found to be most versatile species of the region as it was deployed in 13 diseases of 8 body systems.
Evaluation of alveolar bone support around incisors in patients with unilateral cleft lip, alveolus, and palate in late mixed dentition using cone beam computed tomography
Authors: Pan Yingdan , Zeng Yunting , Zhang Zeyu , Liu Yiqin , Jing Yi , Xiao Liwei 
Published: January 2018

ABSTRACT

Objectives:
To evaluate alveolar bone support around cleft-adjacent maxillary central incisors (U1) in patients with unilateral cleft lip, alveolus and palate (UCLAP) in the late mixed dentition and to investigate the correlation between the alveolar bone thickness (ABT) and tooth inclination.

Materials and Methods:
Cone beam computed tomography scans of 45 subjects with UCLAP (29 boys, 16 girls; mean age = 10.74 ± 1.08 years) were assessed. The distance between the cementoenamel junction (CEJ) and alveolar bone crest (AC), and the ABTs at 3 mm, 6 mm, and the apex were measured on the labial, lingual and distal surfaces of U1. The cleft and normal sides were compared using a paired t-test and Pearson's χ2 test. Pearson's correlation was used to explore the association between the ABT and tooth inclination of cleft-adjacent U1 in the labiolingual and mesiodistal dimensions.

Results:
The CEJ-AC distances were significantly greater in cleft-adjacent U1 (P &lt; .01), with more bone height reduction observed labially and distally (P &lt; .001). The labial, lingual, and apico-distal ABTs were decreased on the cleft side (P &lt; .01). A positive correlation was found between the apico-labial ABT and the labiolingual inclination (r = 0.568, P &lt; .01).

Conclusions:
Patients with UCLAP have reduced alveolar bone support around the cleft-adjacent U1, and the apico-labial ABT tends to decrease with increasing lingual tooth inclination; however, the correlation was weak.
Stimulating economic recovery through euro area growth poles: call for more directed unconventional monetary policy measures?
Authors: Kotlebova Jana , Siranova Maria 
Published: January 2018

Research background: Transfer of newly created money through unconventional monetary measures follows the official European Central Bank distribution key. Yet, it does not take into account the ability of individual countries to drive growth process in other economies. Money spent to boost domestic credit provisioning in growth pole-like economies is more likely to spill over to other adjoined economies and help them to recover, even in the presence of depressed domestic demand and/or overleveraged domestic banking sector.
Purpose of the article: This paper reports growth pole scores for 19 euro area countries, and compares it to the official distribution key used to transmit newly created source of funding.
Methods: We modify the procedure developed in World Bank (2011) for growth pole com-putation in order to account for strength of linkages connecting member states.
Findings & Value added: Our results suggest that the official distribution key might not be completely optimal once looking at the growth pole scores. Countries small in economic size (Baltic states, Slovakia and Slovenia) would benefit from a more differentiated distribution, as they strongly outperform their benchmark set by the official distribution key. On the other hand, big euro area economies do not achieve the levels used in official distribution key, taking into account their growth pole potential for other euro area economies.
Black Chocolate Consumption Reduces Subjective Symptoms in 18-22 Years Old Females with Premenstrual Syndrome
Authors: Nurazizah Eliza , Tih Fen , Suwindere Winny 
Published: January 2018

Menstruation is the release of the endometrium with bleeding every month, except during pregnancy. Before or during menstruation, a woman may experience stiffness or abdominal cramps, mood fluctuations and other physical and psychological disorders, which is termed as premenstrual syndrome (PMS). The aim of this research is to observe and value the effect of dark chocolate on clinical symptoms of PMS. This research is an experimental prospective, using experimental design with one group pre and post test. Subjects were 30 women aged 18-22 years. Every day for 2 weeks before menstruation period, subjects took 20 gram of dark chocolate, then were asked to answer questionaire. The data measured is the score as well as individual PMS symptoms before and after eating dark chocolate, was analyzed using a nonparametric Wilcoxon test, followed by McNemar chi square with α=0.05. A highly significant decrease was found in anxiety symptoms, whereas statistically significant reduction was found in fatigue or feeling tired, cramps abdominal, bloating, diarrhea, headache, back pain, change in appetite, muscle or joint pain, and problems in concentration. But the symptom of acne complaint was increased from 73.3% to 76.7%. Consumption of dark chocolate reduces premenstrual syndrome scores on women aged 18-22 years. Keywords: dark chocolate, premenstrual syndrome
RELATIONSHIPS BETWEEN DECIDUOUS TEETH PREMATURE LOSS AND MALOCCLUSION INCIDENCE IN ELEMENTARY SCHOOL IN CIMAHI
Authors: Herawati Hillda , Sukma Novita , Utami Rainisa Dewi 
Published: January 2018

Premature loss of deciduous teeth is defined as the loss of deciduous teeth before they approach the eruption of the permanent teeth. The aim of this study is to find out the relationship between premature loss of deciduous teeth and the malocclusion according to the Angle’s Classification on Elementary School students children in Cimahi. The type of this research is analytic with a cross sectional research design. The samples are 77 students (7-11 year-old). The sampling method is cluster random sampling. The result shows that the prevalence of premature loss of deciduous teeth was 36.4% and the prevalence of malocclusion is 76.62%. Base on Angle’s Classification, it is revealed that 23.4% of the population has normal occlusion. The percentage of Angle’s class I malocclusion is 45,5%, class II is 23.4% and class III is 7.8%. There is a significant relationship between premature loss of deciduous teeth and its malocclusion (p-value = 0,000). It is concluded that all the students have premature loss of deciduous teeth with malocclusion. Keywords: Premature Loss, Deciduous Teeth, Malocclusion
The Effect of Chicken (Gallus gallus domesticus) Eggshell’s Powder towards Wound Healing of Incision Wound on Male Swiss-Webster Mice
Authors: Nugraha Rahman A. , Pramono Harijadi , Wahyudianingsih Roro 
Published: January 2018

Domestic chicken eggshells contain calcium and protein that could be useful in wound healing process. This research was conducted to determine whether domestic chicken eggshells can accelerate wound healing. Twenty one male Swiss-Webster mice with 2 cm incision were divided into 3 groups. Negative control group were given Carboxymethyl cellulose 1% (CMC), positive control group were given feracrylum 1% (FER), and the eggshells group given domestic chicken eggshells powder (KT). Treatment and data mesurement was measured every day until the 7th day. On the 7th day the average length of the wound were analyzed and the skin tissue is taken for microscopic examination. Data analyzed using one-way ANOVA followed by Post Hoc Least Significant Difference (LSD) with p=0,05. On macroscopic examination, there were highly significant differences between KT compared to CMC and highly significant differences between KT compared to FER. the average length of wound on the 7th day on KT 0,63 cm shorter than CMC 1,07 (p=0,000) and FER 0,81 cm (p=0,003). On microscopic examination, the degree of reepithelization on KT groups are severe, moderate for collagen density, fibroblasts density, subepithelial neutrophil density, degree of edema, and mild for angiogenesis. We conclude domestic chicken eggshells powder can accelerate wound healing. Key words: domestic chicken eggshells, incision wound, wound healing
Evaluasi Diri Perilaku Profesional di Institutsi Sekolah Tinggi Ilmu Kesehatan Guna Bangsa Yogyakarta
Authors: Widuri Widuri , Kumara Amitya , Hadianto Tridjoko 
Published: January 2018

Background: Education world has a very important role in improving the quality of human resources, as it is the environment in which the process of the formation of professional behavior through a series of teaching and learning process. Professional behavior should be clearly seen as an aspect of personal identity and character developed over time. Based on this, the focus of professionalism began to shift from individual to the institution and stated that professionalism must be embedded in an educational institution with a complete integration of the culture of professionalism that involves the institution leader, staffs, lecturers, and students. The purpose of this study is to investigate the professional behavior of the institution of Sekolah Tinggi Ilmu Kesehatan Guna Bangsa Yogyakarta.
Methods: This study is a descriptive qualitative research. Subjects were the institutional leader, lecturers, staffs and students are determined by purposive sampling. Interview instruments include altruism, honor and integrity, caring and compassion, respect for others, responsibility and accountability, excellence and scholarship, and leadership. Participant at the data collection focused group discussion (FGD) is 10 persons and on interview data collection is 21 persons. Efforts to achieve the credibility of the informant are done by triangulation and discussions with colleagues. Research supervisor role as auditors, maintain dependency and certainty degree of this research.
Results: Participants considered that the lecturers, staffs, students and institutional leader have done with the guidance of a good, high integrity, good communication, mutual respect, responsibility and provide exemplary. However, some behavioral components still require improvement such as the level of lecturers’ discipline, staffs’ job and responsibility distribution, student discipline and responsibility, and supervisor leadership patterns.
Conclusion: As there are still some components of professional behavior that needs any improvement, requires institutions to increase self-understanding and awareness to professional behavior. Institutions need to consider any strategies to be taken to overcome any problems faced by the institution to achieve professional behavior.
Perbedaan Self Assessment dan Peer Assessment Terhadap Kompetensi Pemasangan Infus Ditinjau dari Motivasi
Authors: Devianto Aan , Soebiyanto AA. , Wujoso Hari 
Published: January 2018

Background: There are different assessment methods that aim to evaluate the learning process of students, such as formative or summative methods. The assessment methods that are still rarely used in nursing education are self-assessment and peer assessment. Therefore, in order to determine whether these methods have advantages or disadvantages, investigation is needed. The research that is conducted with these methods is a research on the competencies on infusion installment that is also assessed from the students’ motivation to follow the learning process.
Subjects and Methods : This research is a quantitative research using true experimental approach. The population is the students. The samples are obtained by using random sampling. The independent variables in this study are a self -assessment, peer assessment and motivation, while the dependent variable is the infusion installment competency. There are three purposes of this study. The first is to analyze the differences in self-assessment and peer-assessment of infusion installment competence. The second is to analyze the differences of motivation on infusion installment competence. The last is to analyze the interaction between the assessment of the competence models and the level of motivation on infusion installment. Two-path analysis of variance (ANOVA) was used to test statistical data.
Results: The results showed that there were significant differences between self-assessment and peer-assessment of competence on infusion installment with the results of p= 0.000. Other results also showed a significant difference between high motivation and low motivation on infusion installment competence with the results of p= 0.002. In addition to that, the statistical test also showed the interaction between the models of the assessment and the motivation on infusion installment competence with p = 0.000. Additionally, there are also some treatment groups that were not significant with p= scores > 0.05.
Pengaruh Lama Penyimpanan Susu Kedelai dalam Lemari Es Terhadap Pertumbuhan Bakteri Psikrofilik
Authors: Khotib Bayu Nur , Prasetyaningsih Yuliana , Nadifah Fitri 
Published: January 2018

Background: Soy milk is a drink with full of nutrients, especially contains high protein and vitamin. In room’s temperature, soy milk easy to be damage because of bacterial’s activity. Storaging in low temperature is one of control effort to prevent damaging in soy milk.
Research Purpose: To find out whether there is influence of soy milk long-time storaging in refrigator toward bacterial psychrophilic’s growth.
Research methods: Methods which use in this research is quasi experimental with pre and post test with control design program. Intervention to sample is storaging the sample in refrigator during 1 until 5 days.
Results: Data results obtained from this research was the highest number of colony’s growth occured in days 3 with 4733,33 CFU/ml and that number not exceed yet the bacterial pollution number based on soy milk SNI that is 1 x 106.
Conclusion: There was influence of soy milk long-time storaging in refrigator toward bacterial psychrophilic’s growth.
Hubungan Kepatuhan Prosedur Tetap Perawatan Ulkus Diabetikum dengan Kepuasan Pasien Diabtes Melitus Pengguna BPJS PBI di RSUD Sleman
Authors: Widuri Widuri , Sari Dwi Agustiana , Faisal Akhmad 
Published: January 2018

Background: Satisfaction is the degree of one's feelings after comparing the performance or results which felt with expectations. In this case the patient satisfaction as a benchmark the quality of Sleman hospital where the vision and mission is a quality health service delivery. Especially for compliance using SOP, the Sleman hospital is part of the process of achieving Satisfaction Patient Diabetes Mellitus User BPJS PBI at Sleman Hospital.
Objective:Knowing the relationship between compliance procedures care diabetic ulcers with satisfaction the patient diabetes mellitus user BPJS PBI at Sleman Hospital.
Methods:This research is research non experiment using the design descriptive correlative.This research was at Sleman Hospital, from May to July. With the methods samples being used were a total of sampling and the number of samples in this research is 26 of respondents.
Result:Of the 26 respondents there are as many as 23 nurses (88.5%) carry out the action in accordance with procedures still make a high percentage of the level of satisfaction.
Conclusions:There is a correlation between compliance procedures care diabetic ulcers with satisfaction the patient diabetes mellitus user BPJS PBI at Sleman Hospital,with the result Asymp.Sig(2-sided)0,001<0,05.