bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of telehealth is associated with improved timeliness to kidney transplant waitlist evaluation
Authors: Forbes Rachel C , Broman Kristy Kummerow , Johnson Tommy B , Rybacki Diane B , Hannah Gillis Angela E , Hagemann Williams Margarethe , Shaffer David , Feurer Irene D , Hale Douglas A 
Published: June 2017

Introduction The United States Department of Veterans Affairs (VA) National Transplant Program has made efforts to improve access by introducing Web-based referrals and telehealth. The aims of this study were to describe the programmatic implementation and evaluate the effectiveness of new technology on the timeliness to kidney transplant evaluation at a VA medical centre. Methods Between 1 January 2009 and 31 May 2016, 835 patients were approved for evaluation. Monthly data were summarized as: number of applications, median days to evaluation, and median percentage of evaluations that occurred within 30 days. Temporal trends were analysed using non-parametric comparisons of medians between three eras: Pre Web-based submission, Web-based submission, and Web-based submission with videoconference (VC) telehealth. Results The number of applications did not vary between eras ( p = 0.353). The median time to evaluation and the median percentage of patients with appointments within 30 days improved significantly in the Web-based submission with VC era when compared with the Web-based and Pre Web-based eras (37 vs. 260 and 116 days, respectively, p < 0.001; 100% vs. 8% and 0%, respectively, p < 0.001). Discussion We have been able to markedly improve the timeliness to kidney transplant waitlist evaluation with the addition of telehealth.
Predictors of post-traumatic stress disorder following critical illness: A mixed methods study
Authors: Battle Ceri E , James Karen , Bromfield Tom , Temblett Paul 
Published: June 2017

Purpose Post-traumatic stress disorder has been reported in survivors of critical illness. The aim of this study was to investigate the predictors of post-traumatic stress disorder in survivors of critical illness. Materials and methods Patients attending the intensive care unit (ICU) follow-up clinic completed the UK-Post-Traumatic Stress Syndrome 14-Questions Inventory and data was collected from their medical records. Predictors investigated included age, gender, Apache II score, ICU length of stay, pre-illness psychopathology; delirium and benzodiazepine administration during ICU stay and delusional memories of the ICU stay following discharge. Results A total of 198 patients participated, with 54 (27%) patients suffering with post-traumatic stress disorder. On multivariable logistic regression, the significant predictors of post-traumatic stress disorder were younger age, lower Apache II score, pre-illness psychopathology and delirium during the ICU stay. Conclusions The predictors of post-traumatic stress disorder in this study concur with previous research however a lower Apache II score has not been previously reported.
La comisión histórica el conflicto del conflicto en Colombia: la construcción de visiones del rol de las fuerzas armadas de Colombia en el conflicto y sus efectos en las relaciones cívico militares
Authors: Torrijos-R Vicente , Arévalo-Ramírez Walter 
Published: June 2017

Reconociendo la relevancia que tienen las comisiones históricas en el diseño de las relaciones cívico-militares en escenarios de posconflicto, el documento identifica las diferentes posturas que el informe de la Comisión Histórica en Colombia contiene respecto al rol de las Fuerzas Militares en el conflicto, evidencia sus consecuencias y narrativas y resalta las posibilidades y preocupaciones que pueden derivarse de narrativas que condenen a las Fuerzas Militares y afecten su capital simbólico y su legitimidad
Long-QT syndrome-associated caveolin-3 mutations differentially regulate the hyperpolarization-activated cyclic nucleotide gated channel 4
Authors: Motloch LJ , Larbig R , Darabi T , Reda S , Motloch KA , Wernly B , Lichtenauer M , Gebing T , Schwaiger A , Zagidullin N , Wolny M , Hoppe UC 
Published: June 2017

Background
Caveolin-3 (cav-3) mutations are linked to the long-QT syndrome (LQTS) causing distinct clinical symptoms. Hyperpolarization-activated cyclic nucleotide channel 4 (HCN4) underlies the pacemaker current If. It associates with cav-3 and both form a macromolecular complex.

Methods
To examine the effects of human LQTS-associated cav-3 mutations on HCN4-channel function, HEK293-cells were cotransfected with HCN4 and wild-type (WT) cav-3 or a LQTS-associated cav-3 mutant (T78M, A85T, S141R, or F97C). HCN4 currents were recorded using the whole-cell patch-clamp technique.

Results
WT cav-3 significantly decreased HCN4 current density and shifted midpoint of activation into negative direction. HCN4 current properties were differentially modulated by LQTS-associated cav-3 mutations. When compared with WT cav-3, A85T, F97C, and T78M did not alter the specific effect of cav-3, but S141R significantly increased HCN4 current density. Compared with WT cav-3, no significant modifications of voltage dependence of steady-state activation curves were observed. However, while WT cav-3 alone had no significant effect on HCN4 current activation, all LQTS-associated cav-3 mutations significantly accelerated HCN4 activation kinetics.

Conclusions
Our results indicate that HCN4 channel function is modulated by cav-3. LQTS-associated mutations of cav-3 differentially influence pacemaker current properties indicating a pathophysiological role in clinical manifestations.
Spontaneous otoacoustic emission recordings during contralateral pure-tone activation of medial olivocochlear reflex
Authors: Bulut E , Öztürk L 
Published: June 2017

We hypothesized that cochlear frequency discrimination occurs through medial olivocochlear efferent (MOCE)-induced alterations in outer hair cell (OHC) electromotility, which is independent from basilar membrane traveling waves. After obtaining informed consent, volunteers with normal hearing (n = 10; mean age: 20.6 ± 1.2 years) and patients with unilateral deafness (n = 10; mean age: 30.2 ± 17.9 years) or bilateral deafness (n = 8; mean age: 30.7 ± 13.8 years) underwent a complete physical and audiological examination, and audiological tests including transient evoked otoacoustic emission and spontaneous otoacoustic emission (TEOAE and SOAE, respectively). SOAE recordings were performed during contralateral pure-tone stimuli at 1 and 3 kHz. SOAE recordings in the presence of contralateral pure-tone stimuli showed frequency-specific activation out of the initial frequency range of SOAE responses. Basilar membrane motion during pure-tone stimulation results from OHC activation by means of MOCE neurons rather than from a traveling wave. Eventually, frequency-specific responses obtained from SOAEs suggested that OHC electromotility may be responsible for frequency discrimination of the cochlea independently from basilar membrane motion.
Beyond Public Particpation: The disjuncture between South Africa's Environmental Impact Assessment (EIA) Law and Sustainable Development
Authors: Murombo T 
Published: June 2017

One of the key strategies for achieving sustainable development is the use of the process of evaluating the potential environmental impacts of development activities. The procedure of environmental impact assessment (EIA) implements the principle of integration which lies at the core of the concept of sustainable development by providing a process through which potential social, economic and environmental impacts of activities are scrutinised and planned for. Sustainable development may not be achieved without sustained and legally mandated efforts to ensure that development planning is participatory.

The processes of public participation play a crucial role in ensuring the integration of the socio-economic impacts of a project into the environmental decision-making processes. Public participation is not the only process, nor does the process always ensure the achievement of sustainable development. Nevertheless, decisions that engage the public have the propensity to lead to sustainable development. The public participation provisions in South Africa’s EIA regulations promulgated under the National Environmental Management Act 107 of 1998 show a disjuncture between the idea of public participation and the notion of sustainable development. The provisions do not create a framework for informed participation and leave a wide discretion to environmental assessment practitioners (EAPs) regarding the form which participation should assume. In order for environmental law, specifically EIA laws, to be effective as tools to promote sustainable development the laws must, among other things, provide for effective public participation. The judiciary must also aid in the process by giving content to the legal provisions on public participation in the EIA process.
Die Impak en Grondwetlikheid van die Reg om te Staak met Betrekking tot Noodsaaklike Dienste – 'n Vergelykende Studie
Authors: Deacon HJ , Cilliers PQ 
Published: June 2017

This article critically considers the application of and necessity for the right to strike, especially regarding employees that are employed in an essential service. The South African position is examined and compared to other countries around the world, but the focus is mainly on the United Kingdom.
The article shows that South Africa's current labour legislation (especially regarding essential services) is in theory good, but that it is applied and enforced poorly in spite of the provisions contained in the Labour Relations Act and the Constitution of the Republic of South Africa 1996. This became evident in the 2007 public workers' strike in which many essential services employees took part.
The United Kingdom, Australia, New Zealand, Canada, India, France and Kenya all have different ways of dealing with strikes and essential services. Some of these countries' approaches are similar to South Africa's, but in each there is some difference that could be useful in the South African situation. Through these comparisons it becomes clear that the right to strike is important in many countries around the world, but that each country's essential services (or services that can be classified as essential) are equally important. Every country places at the very least some limitation on the right of essential services employees to strike.In conclusion this article states that the South African Labour Law is not perfect and can be improved by means of comparison. This improvement is of vital importance to the lives, health and personal safety of every individual in the country.
Judging Under a Bill of Rights
Authors: Harms Louis TC 
Published: June 2017

We are pleased to publish here, as an oratio, the Ebsworth Memorial Lecture delivered by Mr Justice Louis Harms in February 2007. In his lecture he addressed a range of contentious issues regarding the challenges of judging under a (new) Bill of Rights and he inter alia raises, "without answering, the question of whether a bill of rights should reflect existing societal values or whether it should create them." He also spoke candidly of judicial activism, verbosity emanating from the bench, the judiciary and the separation of powers and (in-)consistency in constitutional adjudication. Among his conclusions he states that a Bill of Rights "is supposed to remove arbitrariness, not only of legislation but also of adjudication."
Do Different Instruction Modalities Matter? Exploring the Influence of Concept Mapping and Translation Strategies Instruction on the Reading Comprehension Ability of Adult EFL Learners
Authors: Davaribina Mehran , Asl Shahram Esfandiari 
Published: June 2017

The present study was an attempt to compare the effect of concept mapping strategy instruction and translation strategy instruction on the reading comprehension ability of the Iranian EFL learners. To do so, 90 EFL learners at the intermediate level studying in a language institute in Ardabil, north Iran were randomly assigned into three equal groups (concept map, translation and control). Having taken a reading pretest, the participants in experimental groups were instructed using mentioned strategies whereas the control group learners were taught the same content with no strategies integrated. Results of analysis of covariance (ANCOVA) revealed that the participants in the experimental groups significantly outperformed the participants in the control group, suggesting that the application of concept mapping and translation strategy training can generate more positive effect on the reading comprehension ability of the learners. Also, the findings of the study indicated that the concept mapping group outperformed the translation strategy group on the reading posttest. Pedagogical implications and suggestions of the study will be discussed.
Governança digital como vetor para uma nova geração de tecnologias de participação social no Brasil | Digital governance as a vector for a new generation of social participation technologies in Brazil
Authors: Parra Filho Henrique Carlos Parra , Martins Ricardo Augusto Poppi 
Published: June 2017

RESUMO O desenvolvimento das TICs aponta para a emergência de uma democracia que promete, entre outras coisas, protagonismo da sociedade em relação ao Estado e distribuição de poder. Nos últimos anos, houve uma explosão de iniciativas governamentais e cívicas que se articulam em relação a essa promessa ainda não respondida. O presente artigo assume como pressuposto a emergência dessa sociedade em rede, lança mão do conceito de governança digital para relatar a experiência recente do Instituto Cidade Democrática e propor uma nova geração de tecnologias produzidas em arranjos de coprodução entre Estado e sociedade que logrem a inclusão de grupos sociais vulneráveis politicamente.Palavras-chave: Governança Digital; TICs; Participação Social; Inclusão; Manipulação.ABSTRACT The development of ICTs leads to the emergence of a democracy that promises, among other things, a prominent role of society in relation to the State and distribution of power. In recent years, there has been an explosion of government and civic initiatives that are articulated in relation to this promise, but largely unanswered. This article assumes the emergence of this networked society, uses the concept of digital governance to report on the recent experience of the Instituto Cidade Democrática and propose a new generation of technologies produced in coproduction arrangements between State and Society that achieve inclusion for politically vulnerable social groups.Keywords: Digital Governance; ICTs; Social Participation; Inclusion; Manipulation.
Laboratórios empáticos | Emphatic labs
Authors: Mendonça Cinthia 
Published: June 2017

Resumo O artigo trata de laboratórios que se dedicam à materialização de ideias por meio do trabalho colaborativo. O trabalho colaborativo que se pode encontrar nestes espaços faz referência a ideia de commons, isto é, através dele podemos encontrar compartilhamentos em diferentes níveis, sobretudo, através da criação de laços sociais, políticos, científicos e ainda a gestão de recursos. São espaços de experimentação (tecnosocial, artística ou científica) que não necessitam de uma estrutura rígida para serem eficientes; ao contrário, é criando dispositivos para destituir estruturas como essa que poderão ser empáticos e inclusivos. Os laboratórios, se pensados como instâncias mais corporificadas e menos institucionalizadas, podem funcionar como um dispositivo de proliferação de fluxos de informações, até que estas ganhem forma.Palavras chave: Trabalho Colaborativo; Commons; Espaços Empáticos.Abstract The article analyses laboratories dedicated to the collaborative materialization of ideas through collaborative work. These refer us to the concept of commons, the sharing of spaces that refer us to technosocial, artistic or scientific experimentation which avoids rigid structures. They thus produce social, political, and scientific ties as well as the management of resources and may become empathic and inclusive. These less institutionalized structures can stimulate the proliferation of information flows until these gain form.Keywords: Collaborative Work; Commons; Empathic Spaces.
A ELEVAÇÃO DO HOMEM RURAL: institutos de educação rural e a cooperação da Misereor
Authors: FRANZEN DOUGLAS ORESTES 
Published: June 2017

O artigo analisa a gênese de implantação dos Institutos de Educação Rural no Rio Grande do Sul através da cooperação da Misereor na década de 1970. A proposta é de correlacionar realidades locais diante de uma conjuntura mais abrangente que condicionou a postura social da Igreja Católica bem como influenciou nas demandas do espaço rural do estado. Defende-se a ideia de que os Institutos de Educação Rural representaram uma proposta de modernização da agricultura sob a tutela do catolicismo. Palavras-chave: Misereor. Catolicismo. FAG. Instituto de Educação Rural.THE ELEVATION OF RURAL MAN: institutes of rural education and the cooperation of MisereorAbstract: The article analyzes the genesis of implantation of the Institutes of Rural Education in Rio Grande do Sul through the cooperation of Misereor in the 1970s. The proposal is to correlate local realities in the face of a more extensive context that conditioned the social position of the Catholic Church as well as influenced the demands of the rural area of the state. It ´s defended the idea that the Institutes of Rural Education represented a proposal of modernization of the agriculture under the tutelage of the Catholicism.Keywords: Misereor. Catholicism. FAG. Institut of Rural Education.LA ELEVACIÓN DEL HOMBRE RURAL: institutos de educación rural y la cooperación de Misereor Resumen: El artá­culo analiza la génesis de la aplicación de los Institutos de Educación Rural en Rio Grande do Sul a través de la cooperación de Misereor en la década de 1970. La propuesta consiste en correlacionar las realidades locales que enfrentan un contexto más amplio que condicionó la posición social de la Iglesia Católica e influyó en las demandas de espacio de estado rural. Se defiende la idea de que los Institutos de Educación Rural representaban una propuesta de modernización de la agricultura bajo la tutela del catolicismo.Palabras clave: Misereor. Catolicismo. FAG. Instituto de Educación Rural.
FRONTEIRAS DINá‚MICAS: propriedade de terra e trabalho indá­gena nos sertões fluminenses (1800-1810)
Authors: MACHADO MARINA MONTEIRO 
Published: June 2017

O presente artigo reflete sobre o processo de ocupação colonial do Rio de Janeiro na passagem do século XVIII para o século XIX, com um olhar especá­fico sobre a construção de aldeamentos indá­genas como estratégia para conquista de terra e controle da mão de obra dos grupos nativos. Para tanto, propõe-se uma revisão do conceito de fronteira e suas aplicações em estudos sobre a expansão territorial realizada nos processos colonizadores. Palavra-chave: Fronteiras. Propriedades. Aldeamento.DYNAMIC FRONTIERS: property of land and indigenous labor in the Rio de Janeiro lands (1800-1810)Abstract: This article reflects on the process of colonial occupation of Rio de Janeiro during the transition from the 18th century to the nineteenth century, with a look specifically on the construction of indigenous villages as a strategy for conquest of land and control of labor of indigenous groups. To this end, it proposes a revision of the concept of the frontier and its applications in studies on the territorial expansion undertaken in cases colonizers.Keyword: Borders. Properties. Holiday.FRONTERAS DINáMICAS: propiedad de tierra y trabajo indá­gena en los sertones de Rá­o de Janeiro (1800-1810) Resumen: El presente artá­culo reflexiona sobre el proceso de ocupación colonial de Rá­o de Janeiro en el pasaje del siglo XVIII hacia el siglo XIX, con una mirada especá­fica sobre la construcción de aldeanos indá­genas como estrategia para conquista de tierra y control de la mano de obra de los grupos nativos. Para ello, se propone una revisión del concepto de frontera y sus aplicaciones en estudios sobre la expansión territorial realizada en los procesos colonizadores.Palabras clave: Fronteras. Propiedad. Aldeas indá­genas.
O método ético da Eudêmia
Authors: Oliveira Mariane Farias de 
Published: June 2017

Tradução do artigo "Eudemian Ethical Method", de Lawrence Jost, publicado originalmente em Essays in Ancient Greek Philosophy IV: Aristotle's Ethics edited by John P. Anton and Anthony Preus, the State University of New York Press ©1991, State University of New York. A tradução foi feita sob supervisão do orientador prof. Dr. José Lourenço Pereira da Silva (UFSM).
Antinociceptive and respiratory effects following application of transdermal fentanyl patches and assessment of brain μ-opioid receptor mRNA expression in ball pythons
Authors: Kharbush Rima J. , Gutwillig Allison , Hartzler Kate E. , Kimyon Rebecca S. , Gardner Alyssa N. , Abbott Andrew D. , Cox Sherry K. , Watters Jyoti J. , Sladky Kurt K. , Johnson Stephen M. 
Published: June 2017

Abstract
OBJECTIVE To quantify plasma fentanyl concentrations (PFCs) and evaluate antinociceptive and respiratory effects following application of transdermal fentanyl patches (TFPs) and assess cerebrospinal μ-opioid receptor mRNA expression in ball pythons (compared with findings in turtles).
ANIMALS 44 ball pythons (Python regius) and 10 turtles (Trachemys scripta elegans).
PROCEDURES To administer 3 or 12 μg of fentanyl/h, a quarter or whole TFP (TFP-3 and TFP-12, respectively) was used. At intervals after TFP-12 application in snakes, PFCs were measured by reverse-phase high-pressure liquid chromatography. Infrared heat stimuli were applied to the rostroventral surface of snakes to determine thermal withdrawal latencies after treatments with no TFP (control [n = 16]) and TFP-3 (8) or TFP-12 (9). Breathing frequency was measured in unrestrained controls and TFP-12–treated snakes. μ-Opioid receptor mRNA expression in brain and spinal cord tissue samples from snakes and turtles (which are responsive to μ-opioid receptor agonist drugs) were quantified with a reverse transcription PCR assay.
RESULTS Mean PFCs were 79, 238, and 111 ng/mL at 6, 24, and 48 hours after TFP-12 application, respectively. At 3 to 48 hours after TFP-3 or TFP-12 application, thermal withdrawal latencies did not differ from pretreatment values or control treatment findings. For TFP-12–treated snakes, mean breathing frequency significantly decreased from the pretreatment value by 23% and 41% at the 24- and 48-hour time points, respectively. Brain and spinal cord tissue μ-opioid receptor mRNA expressions in snakes and turtles did not differ.
CONCLUSIONS AND CLINICAL RELEVANCE In ball pythons, TFP-12 application resulted in high PFCs, but there was no change in thermal antinociception, indicating resistance to μ-opioid-dependent antinociception in this species.