bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Radiomics Model for the Differentiation of Intracranial Solitary Fibrous Tumor/Hemangiopericytoma and Meningioma Based on Multiparametric Magnetic Resonance Imaging
Authors: Xiong Hua , Yin Ping , Luo Weiqiang , Li Yihui , Wang Sicong 
Published: August 2024

Background:
Although the imaging findings of intracranial solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) and meningioma are similar, their treatment and prognosis are quite different. Accurate preoperative identification of these two types of tumors is crucial for individualized treatment.

Objective:
The aim of this study was to develop a radiomics model for the differentiation of intracranial SFT/HPC and meningioma based on multiparametric magnetic resonance imaging (mpMRI).

Material and Methods:
A total of 99 patients from July 2012 to July 2018 with histologically and immunohistochemically confirmed SFT/HPC (n = 40) or meningiomas (n = 59) were retrospectively analyzed. A total of 1118 features were extracted based on its image shape, intensity and texture features. The logistic regression (LR) and multi-layer artificial neural network (ANN) classifiers were used to classify SFT/HPC and meningioma. The predictive performance was calculated using receiver operating characteristic curves (ROC).

Results:
We found significant difference in terms of sex between the SFT/HPC and meningioma group (χ
2
= 4.829, P < 0.05), but no significant difference was found in age (P > 0.05). The most significant radiomics features included five shape and four first-order level features. For the LR classifier, the prediction accuracy of SFT/HPC was 71.0% and meningioma was 78.7%. For the ANN classifier, the prediction accuracy of SFT/HPC was 83.9% and meningioma was 80.9%. Both of the two classifiers achieved a high accuracy rate, but ANN was better.

Conclusions:
Radiomics features, especially when combined with an ANN classifier, can provide satisfactory performance in distinguishing SFT/HPC and meningioma.
A Prospective Study on Perfusion MRI Changes in Intracranial Meningiomas Following Gamma Knife Therapy
Authors: Singh Bhoopendra , Agrawal Deepak , Garg Ajay , Singh Manmohan , Chandra P S , Kale Shashank S 
Published: August 2024

Background:
Radiosurgery plays an important role as a treatment modality for intracranial meningiomas. Perfusion MR imaging can be performed by using arterial spin-labeling (ASL) which is a relatively new and advanced technique.

Objectives:
To assess the changes in perfusion parameters on ASL perfusion MRI in intracranial meningioma after radiosurgery and correlate with histopathological grade of meningioma.

Materials and Methods:
In this Prospective study done at the our institute over a period of 20 months (Jan 2016–Aug 2017), patients with intracranial meningiomas had perfusion MRI with ASL sequence on GE Optima 450W®, 1.5T MRI (GE Medical Systems) prior to GKT and at 6 months after GKT were included in the study.

Results:
Twenty-seven patients were included in this study. Mean cerebral blood flow (CBF) was higher in angiomatous meningiomas. Though mean values of average CBF, maximum, minimum, and SD derived from the ASL MR perfusion were relatively higher in post GKT group as compared to those obtained in pre-GKT but it was not clinically significant. Mean baseline volume of whole cohort was 5.71 cm3 and decreased significantly post GKT in a follow up of 6 months to 5.59 cm3 (P value 0.0018). On comparing volumes of primary and secondary group, volumes were not found be significantly decreased in primary group (P value = 0.1361), 0.1361), but significantly reduced in secondary group (7.13 vs 7.034 cm3) (P value of = 0.0038).

Conclusion:
Our preliminary observations support ASL as a sensitive MRI sequence for the evaluation of meningioma perfusion patterns.
Morphometric Study of the Intracranial Fluid Spaces in Schizophrenia
Authors: Ozdikici Mete 
Published: August 2024

Background:
The intracranial fluid spaces (IFS), also known as “the extra-axial spaces,” consist of the superficial cerebral sulci, the Sylvian fissures, the basal cisterns, the third ventricle, the fourth ventricle, and the two lateral ventricles. In diseases such as schizophrenia, Alzheimer’s, Parkinson’s, and especially hydrocephalus, IFS’ enlargements are observed.

Objective:
Our study aimed to determine the mean values of IFS measurements in patients with schizophrenia and compare them with healthy controls.

Material and Methods:
This work has been carried out on 188 cases, out of which 88 schizophrenia patients (56 men and 32 women) met the diagnostic criteria according to DSM-5 for schizophrenia and 100 healthy controls (50 men and 50 women). The 10 parameters have been used to evaluate IFS on magnetic resonance imaging (MRI) scans.

Results:
The parameters showing statistically significant differences were higher in favor of the individual with schizophrenia. Except for the bifrontal index and Evan’s index, most parameters (the bicaudate index, the fourth ventricle width, the fourth ventricle index, the maximum width of the anterior interhemispheric fissure, the maximum width of the right frontal subarachnoid space, the maximum width of the left frontal subarachnoid space, the maximum width of the right Sylvian fissure, and the maximum width of the left Sylvian fissure) were obtained statistically highly significant differences between the examined and control groups.

Conclusions:
In schizophrenia, it is more practical to evaluate brain atrophy using some parameters, especially the width of the Sylvian fissure and the bicaudate index.
Burden of Noise-Induced Hearing Loss among Rice Mill Workers in Sokoto State, Northwest Nigeria
Authors: Azees Ayotunde S. , Ango Jessica T. , Isa Abdulfattah , Adeniyi Makinde A. 
Published: August 2024

Context:
Work heavily impacts workers' health globally, with noise-induced hearing loss (NIHL) increasingly becoming a major public health concern.

Aim:
This study accessed the prevalence and predictors of noise-induced hearing impairment among local rice mill workers in Sokoto State, Northwest Nigeria.

Materials and Methods:
This cross-sectional study was conducted among rice mill workers between June 2019 and July 2019. Participants were selected using a multistage sampling technique, and a pretested interviewer-administered questionnaire was used for data collection. Data were analyzed using IBM® Statistical Package for the Social Sciences (SPSS) version 22, and the results were presented in tables and figures. Statistical tests of associations were conducted using the Chi-square test and binary logistic regression with a significance level set at P < 0.05.

Results:
The noise level in the rice mills ranged from 81.8 dBA to 91.7 dBA, with a mean of 86.7 ± 2.3 dBA. A hundred and eighty-five respondents (46.5%) of the 398 respondents had at least a symptom of hearing loss, with tinnitus (145 (36.4%)) being the most prevalent. About a third of 125 (32.5%) had hearing impairment in at least one of the ears on audiometry. The predictors of hearing impairment on audiometry were cigarette smoking, education, and having symptoms of hearing loss.

Conclusion:
The burden of noise-induced hearing impairment is high among rice mill workers in Sokoto State, Northwest Nigeria; hence, both the government and rice mill owners need to initiate smoking cessation programs, promote the use of personal protective equipment, and urgently implement hearing conservation programs to address the problem.
Role of A Body Shape Index (ABSI) in Clinical and Public Health Practices: A Correlational Study on Igbo Adults, Southeast Nigeria
Authors: Obaje Sunday G. , Sonia-Love Okorie , Egwu Oguguo A. 
Published: August 2024

Context:
The role of A Body Shape Index (ABSI) has gained attention in both clinical and public health realms due to its potential in predicting health outcomes. This study focuses on Igbo adults in Southeast Nigeria, a population with limited ABSI-related research.

Aim:
It focuses solely on the relationship between ABSI and blood pressure for a healthy living in Nigeria. Research Settings and

Design:
The study enrolled 200 Igbo adults aged 18–25 years. Measurements including height, weight, waist circumference, and blood pressure were collected using measuring tapes, weighing scales, and blood pressure monitors. Statistical analysis employed SPSS version 20, with a significance level of P < 0.05.

Results:
The mean ABSI remained consistent across various age groups and genders. An explicit positive correlation between age and ABSI was observed. Despite a low area under the curve (AUC) of 0.450 in receiver operating characteristic (ROC) analysis, ABSI exhibited optimal predictive capability with a specificity of 77.00% and sensitivity of 35.7%.

Conclusion:
ABSI emerges as a newer and promising alternative index for blood pressure predictions. Its incorporation in clinical and public health practices can enhance disease predictability. This study provides critical insights into the applicability of ABSI within the Igbo population and underscores its potential utility in broader healthcare contexts.
Incidence, Timing, and Possible Risk Factors for Post-Cesarean Wound Infection among Low-Risk Patients in Zaria, Nigeria: A Cross-Sectional Study
Authors: Zubairu Usman D. , Abdul Muhammad A. , Bawa Umma S. , Madugu Nana H. , Ghazzali Sakina 
Published: August 2024

Context:
Rising cesarean section rates worldwide have led to an increase in post-operative complications, especially wound infection, and endometritis. Low-risk cesarean sections are still at risk of these infections despite the absence of common risk factors. The burden and possible risk factors for these have not been widely documented in patients without major risk factors.

Aim:
To determine the incidence, timing of diagnosis, and possible risk factors for wound infection in low-risk cesarean sections.

Settings and Design:
A prospective cross-sectional study conducted among consenting women undergoing low-risk cesarean sections, defined as the absence of established risk factors for post-operative wound infection.

Materials and Methods:
Participants' sociodemographic and obstetric characteristics were documented in a structured proforma. The primary outcome measure was the incidence and timing of wound infection. Secondary outcome measures were the incidences of endometritis and febrile morbidity. The data were analyzed using SPSS version 21 and Windows WINPEPI.

Results:
The incidence of wound infection was 11.2% (19); endometritis—20.6% (35); febrile morbidity—4.1% (7). The mean timing of diagnosis of wound infection and endometritis were 10.22 ± 3.64 and 11.57 ± 3.34 days, respectively. Grandmultiparity (P = 0.007), low maternal educational levels (P = 0.014), endometritis (p = <0.0001), and febrile morbidity (P = 0.017) were the demonstrated risk factors for wound infection.

Conclusion:
The incidence of wound infection in the study population was high and mostly diagnosed after discharge from the hospital. Risk factors for wound infection were grand multiparity, lower educational level, endometritis, and febrile morbidity.
Comparison of Transperineal Ultrasound Cervical Length and Fetal Head- Perineum Distance Measurements with a Simplified Bishop Score in Predicting Induction of Labor Outcome: What is new?
Authors: Usman Mohammed , Adekunle Oguntayo O , Umma S Bawa , Iliyasu Abbas , Joseph B. Igashi 
Published: August 2024

Context:
The goal of Induction of labor (IOL) is to achieve vaginal delivery and reduce cesarean section. The Bishop score (BS) is the gold standard method to assess cervical status, but it is not flawless, leading to unnecessary interventions. Transperineal ultrasound measurements have been compared with the BS in predicting successful IOL. Yet the results are inconsistent.

Aim:
This study aimed to compare transperineal ultrasound measurements and a simplified BS in predicting IOL outcomes at Ahmadu Bello University Teaching Hospital (ABUTH) Zaria.

Settings and Design:
This was a cross-sectional comparative observational study conducted at the labor wards of ABUTH.

Materials and Methods:
It was conducted among women for IOL at 37–42 weeks between June 2019 and February 2020. Ninety-Seven women were recruited. Each woman, had a transperineal ultrasound cervical length (TPUS-CL) and fetal head perineum distance (FHPD) measured. This was followed by a simplified BS assessment.

Statistical Analysis Used:
Relevant Data obtained was entered and analyzed using SPSS version 23. The significance level was considered at P < 0.05.

Results:
The diagnostic accuracy of TPUS-CL (area under the curve (AUC) =0.604, P = 0.084) was better than the simplified BS (AUC = 0.551, P = 0.402). FHPD (P = 0.067, CI = 0.983–1.661) was superior to fetal station (P = 0.832, CI = 0.599–1.890) in predicting the outcome of IOL. The favorable cut-off values for TPUS-CL, FHPD, and BS in our study were ≤ 3 cm, ≤5 cm, and 5 respectively. It demonstrated that TPUS-CL (P = 0.005, AUC = O.750) and FHPD (P = 0.017, AUC = 0.711) are better than simplified BS in predicting success among Primigravidas.

Conclusion:
TPUS-CL and FHPD measurements are better than the simplified BS in predicting IOL outcome in primigravidae.
Knowledge and Perception of Religious Leaders on Premarital Genetic Counseling for Sickle Cell Disease in Kano, Northern Nigeria
Authors: Galadanci Aisha A. , Ibrahim Umma A. , Farouk Zubaida L. , Abdulqadir Ibrahim , Caroll Yvonne , Ding Juan , Kang Guolin , Idris Ibrahim M. , Musa Baba M. , Mukaddas Aisha , Sani Bilya M. , Hussaini Nafiu , Umar Bashir A. , Gambo Awwal , Galadanci Hadiza , Estepp Jeremie H. , Galadanci Najibah A. , DeBaun Michaeel R. 
Published: August 2024

Context:
Nigeria has the highest burden of sickle cell disease in the world. Premarital counseling (PMC) programs to reduce the burden of hemoglobinopathies have been successfully implemented in Muslim predominant countries with similar religious and cultural practices to northern Nigeria. Religious leaders have a significant role to play in the success of PMC in northern Nigeria.

Aims:
To assess the knowledge and perception of premarital genetic counseling for sickle cell disease (SCD) among religious leaders in a culturally and religiously sensitive environment.

Settings and Design:
A cross-sectional (pre and post) study was conducted during the premarital screening workshop for SCD on July 20th, 2019, at Bayero University Kano, northwest Nigeria.

Materials and Methods:
Convenient sampling method was used to identify and invite 126 Islamic clerics through the CICID (Centre for Islamic Civilization and Interfaith Dialogue) at Bayero University Kano, to a premarital screening workshop for SCD. Self-administered semi-structured pre-and posttest questionnaires were used to collect data from the participants. Aminu Kano Teaching Hospital Human Health Research and Ethics Committee approved this study.

Statistical Analysis Used:
Statistical analyses were performed with R version 4.0.2. The data were summarized using descriptive statistics and presented as mean ± standard deviation (SD), median and interquartile range (IQR), and percentages as appropriate. Wilcoxon test for score comparison of pre-and posttest was used with a significance level of 0.05.

Results:
A total of 97 religious' leaders with a mean age ± SD of 44.7 ± 12.7 completed both pre-and posttests. The male-to-female ratio was 5:1. Participants gave more accurate responses to questions during the posttest period than during the pretest; knowledge of the sign of SCD (Proportion of False Discoveries Rate (pFDR) =0.005), knowledge for the complications of SCD (pFDR = <0.001), knowledge for the best time to test for SCD (pFDR = 0.023) and perception for SCD (pFDR = <0.001).

Conclusion:
Providing health education to Islamic clerics improved their knowledge about SCD and their willingness to advocate for PMC to intending couples, and as such, we recommend that religious leaders should be involved in PMC counseling programs.
Seroprevalence of Hepatitis E among Blood Donors in Calabar
Authors: Ushie Godwin Abua , Akaba Kingsley Onorhide , Nwogoh Benedict 
Published: August 2024

Context:
Hepatitis E virus is one of the reemerging pathogens of global concern with an increased risk of transmission by transfusion of blood and blood products. However, this has not been studied in our environment.

Aim:
The aim is to study the seroprevalence of HEV transmission by potential blood donors in Calabar.

Materials and Methods:
This is a cross-sectional study conducted at the UCTH Calabar. A total of 187 potential donors were enrolled. Serum IgM and IgG HEV antibodies were done on 182 donors. IgM and IgG HEV antibodies were measured using an enzyme-linked immunosorbent assay. Data generated were analyzed using the statistical package for social sciences IBM SPSS version 23.

Results:
One hundred and eighty-two participants in the study with a male-to-female ratio of 2.1:1; a mean age and standard deviation of 28.1 ± 5–7 years; 63.7%, 31.9%, and 4.4% of the study population were first-time, regular, and lapsed donors, respectively. Also, 57.1%, 41.8%, and 1.1% of the subject were voluntary, replacement, and remunerated donors; respectively. Fifty percent of the subjects were HEV seropositive, out of which 8.79% were positive for IgM-only anti-HEV antibodies, 86.81% were positive for IgG-only anti-HEV antibodies, and 7.69% were positive for both anti-HEV IgM/IgG antibodies.

Conclusion:
There is a high seroprevalence of HEV (IgM and IgG) among potential blood donors in Calabar. IgM antibodies reflect acute infections which may be subclinical as in our study population while IgG reflects past infection. The relatively high seroprevalence of IgM antibodies obtained in the index study has serious implications for transfusion safety, especially for the immunocompromised persons in the region.
Capillary hemangioma of the eye lid: A rare case in middle age adults
Authors: Pradeep Thanuja G. , Tabassum Seema , Gouri S. R. Mangala 
Published: August 2024

Abstract
Capillary hemangiomas are the most common eyelid lesions seen in children, however, they are rare in middle-aged individuals. They can pose a diagnostic challenge in adults when they present as acquired lesions. We present a case of acquired lid capillary hemangioma in a 48-year-old female with no other predisposing risk factors and the management. In children, spontaneous resolution is a rule, whereas in adults because of the diagnostic dilemma excision biopsy remains the mainstay of management.
Treatment of dry eyes with lifitegrast 5% before cataract surgery: A prospective trial
Authors: Yang Yelin , Gouvea Larissa , Mimouni Michael , Trinh Tanya , Santaella Gisella , Cohen Eyal , Sorkin Nir , Slomovic Allan 
Published: August 2024

Abstract

Objective:
The objective of the study was to evaluate the impact of dry eye treatment on intraocular lens (IOL) biometry measurements and postoperative refractive outcome.

Design:
This study involves a prospective interventional study.

Participants:
Consecutive patients with dry eye disease undergoing cataract surgery were included in the study.

Materials and Methods:
All participants underwent a comprehensive dry eye assessment including the ocular surface disease index (OSDI) questionnaire, Schirmer’s test without anesthesia, corneal fluorescein staining, and conjunctival lissamine green staining. Optical biometry was performed using swept-source optical coherence tomography (IOL Master® 700, Zeiss), and corneal aberrometry was measured using a scanning-slit aberrometer (OPD SCAN III, Nidek). Diagnosis of dry eye was made according to Dry Eye Workshop II. Patients received 6 weeks of treatment of lifitegrast 5% and preservative-free artificial tear eye drops and had repeat testing at the end of 6 weeks. The change in subjective and objective dry eye tests and biometry measurements and the difference in target and postoperative refraction before and after treatment were compared.

Results:
Forty eyes of 21 patients were included in the study. Subjectively, OSDI improved from 26.35 ± 6.24 at baseline to 20.97 ± 8.41 after treatment (P = 0.03). Objectively, corneal staining improved from 1.42 ± 1.78 at baseline to 0.39 ± 0.67 after treatment (P = 0.006). No changes were observed in Schirmer’s test without anesthesia, conjunctival staining, or corneal aberrometry (P > 0.05). Repeated biometry after dry eye treatment showed a change in IOL power difference ≥0.5 diopters in 50% (20) of eyes. Mean absolute error was within 0.25D in 87.5% (35) of eyes after treatment compared to 67.5% at baseline (P = 0.05).

Conclusion:
Dry eye treatment leads to subjective symptom improvement and changes in IOL power calculations and postoperative refractive outcomes. Assessing and treating patients for dry eyes before cataract surgery is important in maximizing refractive outcomes.
An evaluation of wet and dry needling techniques for treating myofascial pain in trapezius muscle – A meta-analysis
Authors: Ramaswamy P. , Saikiran C. H. , Swathi M. , Raj B. Mrudula , Lakshmisasi Poluri 
Published: August 2024

Abstract

Introduction:
Myofascial pain is a common sign of temporomandibular joint disorders and a significant cause of dysfunction in the general population. Although there are many ways to treat it, because of their ease of use and effectiveness in reducing pain, needling therapies, particularly those inside the masticatory muscles, have seen a recent surge in attention.

Aim:
The aim of the study was to evaluate the comparison between wet and dry needling therapies in myofascial pain management.

Materials and Methods:
The following study was built using the PICOS and Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocols. A comprehensive search of the literature utilizing the PubMed search engines with the keywords acupuncture, dry needling, wet needling, botulinum toxin, local anesthesia, and masticatory muscle problems was done. A total of 412 items were found after searching the databases. Finally, the analysis contained 21 publications that met the parameters.

Results:
A statistically significant (P < 0.001) impact on pain reduction was seen by this meta-analysis when comparing wet versus dry needling (mean difference = 0.80, 95% confidence interval = −0.52–2.12, n¼ 7 trials).

Discussion:
The effectiveness of wet and dry needling in treating symptoms of neck discomfort with musculoskeletal origins related to TrPs was compared in this meta-analysis. We found strong evidence that lidocaine, a local anesthetic, used in wet needling reduced pain more effectively than dry needling.

Conclusion:
Evidence from this meta-analysis suggests that in individuals with trigger points (TrPs) associated with symptoms of neck discomfort, lidocaine TrP injection works better than dry needling to reduce pain.
Optimizing pier abutment management using digital approach with nonrigid connector for superior treatment outcomes
Authors: Rathee Manu , Mittal Surbhi , Tomar Sarthak Singh , Diwan Kritika , Balavignesh S 
Published: August 2024

Abstract
In clinical dental practice, missing the first premolar and first molar are a common finding in the maxillary or mandibular arch. The result is a long bridge span in which the canine and the second molar act as terminal abutments and the second premolar act as a pier abutment. Teetering movements are usually observed due to the inclination of terminal abutments intruding during function, with the pier abutment serving as a pivot point. Due to these dislodging forces, the rigid fixed dental prosthesis (FDP) with pier abutment has a higher debonding rate than short-span prosthesis, resulting in marginal leakage and caries. This situation can be avoided using nonrigid connectors that act as stress breakers between the retainer and the pontic. This report describes incorporating a digitally fabricated nonrigid connector to rehabilitate a pier abutment case.