bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public Attitudes Toward Breastfeeding in Public Places in Ottawa, Canada
Authors: Russell Katherine , Ali Amira 
Published: March 2017

Background: In Ontario, Canada, breastfeeding in public is a protected right, yet even with these laws, attitudes toward breastfeeding in public can serve as a barrier to breastfeeding. Research aim: This study assesses public support for breastfeeding in public among adults in Ottawa, Ontario, and examines sociodemographic associations with negative attitudes toward public breastfeeding. Methods: Data from the 2015 Rapid Risk Factor Surveillance System (RRFSS), a population health telephone survey, were obtained for Ottawa. Adults ages 18 years and older were asked whether it was acceptable for a mother to breastfeed her baby in a restaurant and shopping mall ( n = 1,276). Descriptive statistics and regression were used to describe sociodemographic characteristics associated with negative attitudes. Results: Overall, 75% of respondents agreed that it was acceptable for a mother to breastfeed her baby in both a restaurant and shopping mall (restaurant: 78%; shopping mall: 81%). Respondents who did not have children at home, were less educated, had a mother tongue language other than French or English and who were retirees were less likely to support breastfeeding in restaurants and shopping malls. In addition, women and immigrants living in Canada for more than 15 years were less likely to support breastfeeding in shopping malls. Conclusion: Despite a law to support public breastfeeding in Ontario, there is room to improve attitudes toward public breastfeeding. Increased public support for public breastfeeding can support women and children to achieve their feeding goals, particularly for those wanting to exclusively breastfeed.
Triple Antithrombotic Therapy With Aspirin, P2Y12 Inhibitor, and Warfarin After Percutaneous Coronary Intervention
Authors: Verlinden Nathan J. , Coons James C. , Iasella Carlo J. , Kane-Gill Sandra L. 
Published: March 2017

Background: Triple antithrombotic therapy is used in patients who require systemic anticoagulation and undergo percutaneous coronary intervention (PCI) requiring dual antiplatelet therapy. Bleeding with this combination is significant; however, few studies have described outcomes with the use of newer oral P2Y12 inhibitors in this setting. Objectives: We aimed to compare outcomes among patients prescribed triple therapy with prasugrel or ticagrelor compared to triple therapy with clopidogrel in patients who underwent PCI and required warfarin. Methods: We retrospectively evaluated 168 patients who received either prasugrel (n = 32) or ticagrelor (n = 10) and were matched (1:3) to those who received clopidogrel (n = 126) at the time of discharge from the index PCI visit. Matching was performed based on age ±10 years, sex, and indication for PCI. The primary outcome was the incidence of any bleeding during the 12-month follow-up. We also evaluated major adverse cardiovascular and cerebrovascular events (MACCEs). Results: Patient baseline characteristics were similar between groups. There was a significant excess of bleeding in patients who received prasugrel or ticagrelor compared to clopidogrel as part of triple therapy (28.6% vs 12.7%; odds ratio, 3.3; 95% confidence interval, 1.38-8.34). No differences were seen between groups in MACCEs. Conclusions: The use of prasugrel or ticagrelor as part of triple antithrombotic therapy among patients who underwent PCI and received warfarin was associated with significantly more bleeding compared to patients who received clopidogrel. Therefore, higher potency P2Y12 inhibitors should be used cautiously in these patients.
Factors Influencing Exclusive Breastfeeding in Tabuk, Saudi Arabia
Authors: Alzaheb Riyadh A 
Published: March 2017

Background: Breast milk contains all the nutrients infants need for their first 6 months of life. However, only a minority of Saudi Arabian mothers exclusively breastfeed, so the influencing factors must be examined to encourage more to do so. The study aimed to determine the prevalence of exclusive breastfeeding at 6 months and its associated factors in Tabuk, North West Saudi Arabia. Methods: A total of 589 mothers of healthy infants aged between 6 and 24 months were interviewed while attending Well-Baby Clinics within 5 primary health care centers. Interviews deployed a structured questionnaire to collect sociodemographic information and detailed data concerning breastfeeding practices. A logistic regression analysis was then performed on the data to identify the factors independently associated with exclusive breastfeeding practice for infants at 6 months. Results: Exclusive breastfeeding was practiced by 31.4% of mothers for the first 6 months of their infant’s life. The logistic regressions indicated that exclusive breastfeeding at 6 months was less likely to be practiced by working mothers, Saudi nationals, and for babies born via cesarean delivery or at low birth weights. Conversely, the mother’s awareness of the recommended exclusive breastfeeding duration was positively associated with exclusive breastfeeding. Conclusions: Programs promoting 6 months of exclusive breastfeeding should target high-risk groups. Two factors identified by this study are modifiable: working mothers and mothers’ awareness of the exclusive breastfeeding duration recommendation. Strategies to improve exclusive breastfeeding rates should therefore focus on workplace facilities and increasing awareness of the exclusive breastfeeding recommendation.
Persistent and selective upregulation of renin–angiotensin system in circulating T lymphocytes in unstable angina
Authors: Coppo Mirella , Bandinelli Manuela , Chiostri Marco , Poggesi Loredana , Boddi Maria 
Published: March 2017

Introduction: Unstable angina is associated with an acute systemic inflammatory reaction and circulating T lymphocytes are activated. We investigated whether in unstable angina with marked immune system activation a selective upregulation of the circulating T-cell renin–angiotensin system, modulated by angiotensin II, could occur. Methods: We studied 13 unstable angina patients, 10 patients with stable angina and 10 healthy subjects. After T-lymphocyte isolation, mRNAs for angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1-R) were quantified at baseline and after angiotensin II stimulation. ACE activity in cell pellet and supernatant and angiotensin II cell content were measured. Results: Plasma renin activity was similar in controls, stable and unstable angina patients. At baseline ACE and AT1-R mRNA levels were higher ( P<0.05) in T cells from unstable angina patients than in T cells from stable angina patients and controls, and further increased after angiotensin II addition to cultured T cells. ACE activity of unstable angina T cells was significantly higher than that of T cells from controls and stable angina patients. Only in T cells from unstable angina patients did angiotensin II stimulation cause the almost complete release of ACE activity in the supernatant. Conclusions: The circulating T-cell-based renin–angiotensin system from unstable angina patients was selectively upregulated. In vivo unstable angina T cells could locally increase angiotensin II concentration in tissues where they migrate independently of the circulating renin–angiotensin system.
Controlled clinical trials of cell therapy in stroke: Meta-analysis at six months after treatment
Authors: Detante Olivier , Moisan Anaïck , Hommel Marc , Jaillard Assia 
Published: March 2017

Background Cell therapy is promising in experimental studies and has been assessed only in a few studies on humans. Aims To evaluate the effect of cell therapy in humans. Methods We included clinical trials with a control group that reported safety and efficacy six months following treatment. Quality was evaluated and clinical scales data were extracted. Quantitative analysis was based on the standardized means difference (SMD). Among 28 trials published from 1995 to 2016, nine studies (194 patients; 191 controls) were eligible. Publication biases were assessed with the funnel plot and pre-specified explanatory variables were tested with a group analysis and a meta-regression. Results The overall quality was moderate. Cell therapy had a positive effect on the outcome (SMD: 0.57, 95% CI: 0.22–0.92; p = 0.002). The sensitivity analysis showed an upper level of effect size of 0.81 (95% CI: 0.34–1.27; p = 0.001) and a lower level of 0.455 (95% CI: 0.04–0.87; p = 0.03). None of the pre-specified explanatory variable was significantly correlated to outcome: age, ratio infarction/hemorrhage, delay from stroke to treatment, route of administration, cell type, randomization, and blinded outcome assessment. The significant heterogeneity (p = 0.03) was not explained by publication biases (p = 0.09) and was more likely due to methodological and quality differences between the trials. Conclusions This result suggests that cell therapy is beneficial in stroke and is expected to help in the designing of stem cells controlled clinical trials (CCT) in large populations.
Lead-antimony sulfosalts from Tuscany (Italy). XVIII. New data on the crystal-chemistry of boscardinite
Authors: Biagioni Cristian , Moëlo Yves 
Published: March 2017

AbstractBoscardinite, ideally TlPb4(Sb7As2)∑9S18, has been described recently as a new homeotypic derivative of baumhauerite, found at Monte Arsiccio mine, Apuan Alps, Tuscany, Italy. New findings of boscardinite in different mineral associations of this deposit have allowed the collection of new crystal-chemical data. Electron-microprobe analysis of the crystal used for the single-crystal X-ray diffraction study gave (in wt.%): Ag 1.81(5), Tl 12.60(21), Pb 17.99(12), Hg 0.14(5), As 9.36(12), Sb 33.60(27), S 23.41(30),Cl 0.06(1), total 98.97(100). On the basis of ∑Me= 14 apfu, it corresponds to Ag0.42Tl1.52Pb2.14Hg0.02(Sb6.82As3.08)∑9.90S18.04Cl0.04. With respect to the type specimen, these new findings are characterized by a strong Pb depletion, coupled with higher Tl contents, and a significant As enrichment. The single-crystal X-ray diffraction study of this (Tl,As)-enriched boscardinite confirms the structural features described for the type sample. The unit-cell parameters area= 8.1017(4),b= 8.6597(4),c= 22.5574(10) Å, α = 90.666(2), β = 97.242(2), γ = 90.850(2)°,V= 1569.63(12) Å3, space groupP̄1. The crystal structure was refined down toR1= 0.0285 on the basis of 6582 reflections withFo> 4σ(Fo). Arsenic is dominant in threeMeS3sites, compared to one in type boscardinite. The main As-enrichment is observed in the sartorite-type sub-layer. Owing to this chemical peculiarity, (Tl, As)-rich boscardinite shows alternation, alongb, of Sb-rich sites and As-rich sites; this feature represents the main factor controlling the 8 Å superstructure. The chemical variability of boscardinite is discussed; the Ag increase observed here gets closer to stoichiometric AgTl3Pb4(Sb14As6)∑20S36(Z= 1), against possible extension up to AgTl2Pb6(Sb15As4)∑19S36for type boscardinite.
The astrophyllite supergroup: nomenclature and classification
Authors: Sokolova Elena , Cámara Fernando , Hawthorne Frank C. , Ciriotti Marco E. 
Published: March 2017

AbstractHere we report a nomenclature and classification for the astrophyllite-supergroup minerals. The HOH block is the main structural unit in all astrophyllite-supergroup structures; it consists of three H–O–H sheets where the T4O12 astrophyllite ribbons occur in the H sheets. In each structure, HOH blocks alternate with I (Intermediate) blocks along [001]. The twelve minerals of the astrophyllite supergroup are divided into three groups based on (1) the type of self-linkage of HOH blocks, i.e. (a) HOH blocks link directly where they share common vertices of D octahedra, or (b) HOH blocks do not link directly; and (2) the dominant cation of the O sheet (the C group: C7 apfu). In the astrophyllite group (HOH blocks connect via D– XDP–D bridges, Fe2+ is dominant at C7), there are six minerals: astrophyllite, niobophyllite, zircophyllite, tarbagataite, nalivkinite and bulgakite. In the kupletskite group (HOH blocks connect via D–XDP–D bridges, Mn2+ is dominant at C7), there are three minerals: kupletskite, niobokupletskite and kupletskite-(Cs). In the devitoite group (HOH blocks do not connect via D–XDP–D bridges), there are three minerals: devitoite, sveinbergeite and lobanovite. The general formula for the astrophyllite-supergroup minerals is of the form A2pBrC7D2(T4O12)2IXD2OXA4OXDnPWA2, where C [cations at the M(1–4) sites in the O sheet] = Fe2+, Mn, Na, Mg, Zn, Fe3+, Ca, Zr, Li; D (cations in the H sheets) = [6,5]Ti, Nb, Zr, Sn4+ , [5]Fe3+, Mg, Al; T = Si, minor Al; A2pBrIWA2 (I block) where p = 1,2; r = 1,2; A = K, Cs, Ba, H2O, Li, Rb, Pb2+, Na,□; B = Na, Ca, Ba, H2O,□; I represents the composition of the central part of the I block, excluding peripheral layers of the form A2pBrWA2, e.g. (PO4)2(CO3) (devitoite); XDO = O; XAO = OH, F; XDP = F, O, OH, H2O,□, where n = 0, 1, 2 for (XDP)n; WA = H2O,□.
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population
Authors: Hein Nadine , Cameron Donald P. , Hannan Katherine M. , Nguyen Nhu-Y N. , Fong Chun Yew , Sornkom Jirawas , Wall Meaghan , Pavy Megan , Cullinane Carleen , Diesch Jeannine , Devlin Jennifer R. , George Amee J. , Sanij Elaine , Quin Jaclyn , Poortinga Gretchen , Verbrugge Inge , Baker Adele , Drygin Denis , Harrison Simon J. , Rozario James D. , Powell Jason A. , Pitson Stuart M. , Zuber Johannes , Johnstone Ricky W. , Dawson Mark A. , Guthridge Mark A. , Wei Andrew , McArthur Grant A. , Pearson Richard B. , Hannan Ross D. 
Published: March 2017

Key Points
Inhibition of RNA Pol I by CX-5461 treats aggressive AML and outperforms standard chemotherapy regimens. CX-5461 induces p53-dependent apoptosis, p53-independent cell-cycle defects and differentiation, and reduces LICs.
A review of the nomenclature of Gyrogona and Gyrogonites (Fossil Algae: Charophyceae)
Authors: Doweld Alexander B. 
Published: March 2017

AbstractAnalysis of the nomenclature of the fossil genus Gyrogonites Lam. (Algae: Charophyceae) shows that the name was first treated by Lamarck (1801) as an incompletely known fossil mollusk from France. The species was given the name Gyrogonites medicaginulus because of its resemblance to the fruit of Medicago sativa (lucern). The gyrogonites were shown to be fossilized charophycean reproductive structures by Leman in 1812, now understood as calcified female gametangia preserved after the escape or the decomposition of protoplasmic material. Differences in the starting date of zoological nomenclature (1 Jannuary 1758) and that of plant fossils (1 January 1820) are resolved by Art. 45.1 of the botanical code, by which Gyrogonites is acceptable as a validly published pre‐1820 fossil charophycean name even though it was originally treated as a fossil animal. Gyrogona Lam. (1805) is a superfluous renaming of Gyrogonites (still considered at that time as a zoological name for a mollusk) and therefore should be rejected under the botanical and zoological codes. The inclusion of the type of Gyrogonites in the later established fossil higher‐plant genus Bechera Sternb. (1825), a repository genus for vegetative verticillate axes and reproductive organs, renders the latter genus name as nomenclaturally superfluous and illegitimate. Six fossil species of Gyrogonites are validated for the first time, 19 species and related 2 subspecies of Gyrogona are formally recombined into Gyrogonites. Two names, G. lemanii and G. oehlertii, are neotypified, and a lectotype is designated for G. wrightii. Precise dates of publication of the taxonomic works on gyrogonites of Bowdich, Brongniart, Fleming, Lamarck and Parkinson, supplementing records of Taxonomic literature II, are given for the first time.
Report of the Nomenclature Committee on Fossils: 11
Authors: Herendeen Patrick S. 
Published: March 2017

SummaryThe following eight generic names are recommended for conservation: Cathaya Chun & Kuang against Cathaya Karav., Cycadeoidea against Mantellia, Laricoidites against Laevigata-sporites, Pleuromeia with that spelling, Rhabdosphaera against Rhabdolithes, Selenopemphix against Margosphaera, Taeniopteris, and Ullmannia with a conserved type against Anthotypolithes and Cupressites. The following three species names are also recommended for conservation: Cycadeoidea megalophylla against Mantellia nidiformis, Selenopemphix nephroides against Margosphaera velata, Taeniopteris vittata, and Ullmannia bronnii with a conserved type against Anthotypolithes ranunculiformis, Cupressus ullmannii, and Cupressites bituminosus. The following generic name is not recommended for conservation: Laevigatosporites Ibrahim with that spelling against Laevigata-sporites R. Potonié & Gelletich and Laevigatisporites R. Potonié & Gelletich. The following species name is not recommended for conservation: Ephedrites cheniae (Liaoxia cheniae) against Potamogeton jeholensis. The committee judged the names Laevigata-sporites, Laevigati-sporites and Laevigato-sporites in any comparison to be not confusable, regardless of whether spelled with or without the hyphen.
Phylogeny, biogeography, systematics and taxonomy of Salicornioideae (Amaranthaceae/Chenopodiaceae) – A cosmopolitan, highly specialized hygrohalophyte lineage dating back to the Oligocene
Authors: Piirainen Mikko , Liebisch Oskar , Kadereit Gudrun 
Published: March 2017

AbstractSalicornioideae (Amaranthaceae / Chenopodiaceae) comprise 11 genera and ca. 100 species of succulent halophytes distributed worldwide in coastal and inland saline habitats. Most species have peculiar articulated, seemingly leafless stems and spike‐like sessile thyrses with highly reduced flowers hidden by fleshy bracts. We analysed sequence data of four markers (ETS, ITS, atpB‐rbcL, matK‐trnK) from 57 species, 9 subspecies, 1 variety and 2 hybrids representing all curently accepted genera using maximum likelihood, Bayesian analysis, fossil‐calibrated molecular dating and ancestral area analysis. All molecular markers gave similar phylogenetic signals. Salicornioideae probably originated in Eurasia during the late Eocene–early Oligocene. The divergence of the early main clades took place in the middle Oligocene with the separation of Allenrolfea /Heterostachys, Halocnemum /Halopeplis /Halostachys /Kalidium and Arthrocnemum /Microcnemum /Tecticornia /Salicornia/ Sarcocornia lineages. The latter lineage diversified most and comprises ¾ of the species of the subfamily. The Arthrocnemum macrostachyum /Microcnemum lineage diverged at the turn of the Oligocene/Miocene – while the Arthrocnemum subterminale, Tecticornia and Salicornia /Sarcocornia lineages were all present by the middle Miocene. Long‐distance dispersal has taken place several times to the Americas (Allenrolfea /Heterostachys, Arthrocnemum subterminale, Salicornia /Sarcocornia), South Africa (Halopeplis, Salicornia /Sarcocornia) and Australia (Tecticornia, Salicornia /Sarcocornia). Most currently accepted genera were resolved as monophyletic. However, Sarcocornia is paraphyletic in relation to Salicornia, and Arthrocnemum proved to be polyphyletic. In addition, the name Arthrocnemum is a nomenclatural synonym of Salicornia. As a consequence, we propose the merging of Sarcocornia under Salicornia and provide 19 new nomenclatural combinations and one replacement name. For Salicornia (incl. Sarcocornia) we propose a new infrageneric classification to accommodate the four phylogenetically and geographically well‐supported sublineages of the genus. We also propose abandoning the name Arthrocnemum in its current use, and describe two new genera, Arthrocaulon (Eurasia, Africa) and Arthroceras (North America), and provide three new nomenclatural combinations.
Salvia united: The greatest good for the greatest number
Authors: Drew Bryan T. , González-Gallegos Jesús Guadalupe , Xiang Chun-Lei , Kriebel Ricardo , Drummond Chloe P. , Walked Jay B. , Sytsma Kenneth J. 
Published: March 2017

AbstractPrevious molecular phylogenetic research, based on chloroplast and nuclear ribosomal DNA data, has demonstrated that the large genus Salvia (Lamiaceae) is paraphyletic as traditionally circumscribed. However, neither relationships within Salvia s.l. nor within subtribe Salviinae have been evaluated using low‐copy nuclear gene regions. Here, we use two low‐copy nuclear gene regions (PPR‐AT3G09060, GBSSI) to further assess relationships of Salvia and related genera within Salviinae. Our results largely confirm results from previous studies based on chloroplast and nuclear ribosomal DNA. Based upon the phylogenetic results presented here, previous phylogenetic studies, and taxonomic, morphological, and practical considerations, we conclude that the botanical community would be best served by maintaining a broadly defined Salvia, including the five small embedded genera Dorystaechas, Meriandra, Perovskia, Rosmarinus, and Zhumeria as Salvia species. We subsequently present an updated circumscription of Salvia.
Cost Drivers of Versioning: Pricing and Product Line Strategies for Information Goods
Authors: Chellappa Ramnath K. , Mehra Amit 
Published: March 2017

In this paper, we extend the understanding of versioning strategy of an information goods monopolist and provide new insights on when versioning is optimal. To do so, we derive the optimal product line or versions of an information good and the corresponding prices. By relaxing common assumptions on consumers’ usage costs, versioning costs and capital research and development costs, we provide new insights as well as reconcile extant findings on versioning. For a good with no-free-disposal (NFD), i.e., one where consumers have usage costs, our results show that a monopolist’s marginal cost and consumers’ usage costs have the same impact on its versioning strategy, and that these factors are the sole reason for optimality of versioning of information goods. By endogenizing the production of the highest-quality, we show that capital costs create a downward distortion of quality even for the highest types in the market even under full information. Presence of separate versioning costs also lowers the qualities served to the high types and reduces the segment of consumers who are served with product versions. However, versioning costs do not affect market coverage or the price-quality menu itself. Further, when some of the consumer usage costs are absorbed by the firm (as in case of cloud-based provisioning), it does not necessarily lead to market expansion. This paper was accepted by Chris Forman, information systems.
The British local and regional press after Leveson
Authors: Slavtcheva-Petkova Vera 
Published: March 2017

Abstract
The Leveson Inquiry into the culture, practice and ethics of the press is undoubtedly one of the most significant events in the recent history of British media. Lord Justice Leveson’s verdict was damning for the national press but he praised the local press for its contribution to local life and for not succumbing to the ethically questionable practices of the nationals. While the Leveson report did not contain any specific recommendations for the improvement of the regional press, it called for urgent government action to prevent its demise. What happened after Leveson − how have regional and local journalists been affected by the Inquiry and all subsequent developments? This question is at the core of this special issue, which features articles from both academics and practitioners. The authors deal with a wide variety of issues – from normative questions about the role of journalists and (new) business models to more specific enquiries into journalists’ post-Leveson working routines and practices.