bluuebunny/crossref_metadata_2025_split huggingface dataset:
TOR complex 2 localises to the cytokinetic actomyosin ring and controls the fidelity of cytokinesis
Authors: Baker Karen , Kirkham Sara , Halova Lenka , Atkin Jane , Franz-Wachtel Mirita , Cobley David , Krug Karsten , Maček Boris , Mulvihill Daniel P. , Petersen Janni 
Published: May 2016

ABSTRACT
The timing of cell division is controlled by the coupled regulation of growth and division. The target of rapamycin (TOR) signalling network synchronises these processes with the environmental setting. Here, we describe a novel interaction of the fission yeast TOR complex 2 (TORC2) with the cytokinetic actomyosin ring (CAR), and a novel role for TORC2 in regulating the timing and fidelity of cytokinesis. Disruption of TORC2 or its localisation results in defects in CAR morphology and constriction. We provide evidence that the myosin II protein Myp2 and the myosin V protein Myo51 play roles in recruiting TORC2 to the CAR. We show that Myp2 and TORC2 are co-dependent upon each other for their normal localisation to the cytokinetic machinery. We go on to show that TORC2-dependent phosphorylation of actin-capping protein 1 (Acp1, a known regulator of cytokinesis) controls CAR stability, modulates Acp1–Acp2 (the equivalent of the mammalian CAPZA–CAPZB) heterodimer formation and is essential for survival upon stress. Thus, TORC2 localisation to the CAR, and TORC2-dependent Acp1 phosphorylation contributes to timely control and the fidelity of cytokinesis and cell division.
Activation of C–S Bond by Group 10 Metal Complexes: Reaction of Phosphine Ligand Tethered with Three tert-Butylthiophenyl Groups with Group 10 Metal Compounds
Authors: Takeda Nobuhiro , Tanaka Yusuke , Oma Rin , Sakakibara Fumiaki , Unno Masafumi 
Published: May 2016

Abstract
A new PS3-type tripodal tetradentate ligand, P(2-t-BuSC6H4)3 (1b), was synthesized by reaction of PCl3 with 2-t-BuS(C6H4)Li. Reaction of ligand 1b with NiCl2·6H2O resulted in the elimination of t-BuCl to afford the corresponding 5-coordinate nickel complex, [NiCl{P(2-SC6H4)(2-t-BuSC6H4)2}] 6. In addition, ligand 1b reacted with [PdCl2(PhCN)2] and [PtCl2(cod)] to give 4-coordinate square planar palladium and platinum complexes, [MCl{P(2-SC6H4)(2-t-BuSC6H4)2}] (7: M = Pd, 8: M = Pt), respectively, via the elimination of t-BuCl. Further elimination of t-BuCl from palladium complex 7 proceeded by heating of 7 in CDCl3 at 100 °C for 4 h to form dipalladium complex, [Pd2{P(2-SC6H4)2(2-t-BuSC6H4)}2] (9). The isopropyl-substituted palladium and platinum complexes, [PdCl{P(2-i-PrSC6H4)3}]Cl (3a) and [PtCl2{P(2-i-PrSC6H4)3}] (5), also underwent the elimination of i-PrCl by the thermolysis in CDCl3 at 60 °C to afford the corresponding complexes, [MCl{P(2-SC6H4)(2-i-PrSC6H4)2}] (11: M = Pd, 12: M = Pt). The structures of these complexes were determined by NMR spectroscopy, elemental analyses, and X-ray crystallography.
Development of Domestic Primary School in 20-30s of the Previous Century
Authors: Ханжина  , Khanzhina Tatyana 
Published: May 2016

The article considers features of the domestic education content and organization of the pedagogical process in primary school in 20-30s of the
XX century. The main attention is paid to the features of the primary school functioning in Srednevolzhskiy Region. The educational process
orientation to the forming of schoolchildren pro-active attitude, development of self-dependence and initiativity, trust in bright future of the
country.
What does manual handling mean to you?
Authors: Clarke Clare 
Published: May 2016

Despite increased awareness and training, musculoskeletal injuries within the nursing profession remain high. It has been recognised for many years that the handling and transporting of patients within the hospital environment causes problems for healthcare workers (World Health Organisation (WHO), 1983) and back injuries among hospital workers are a concern (Yassi et al, 2001). This article will focus on questions raised on the training that is provided to protect staff and patients from musculoskeletal injury, and ask the question, why do staff seem to be apathetic towards the importance of training in safe manual handling? The introduction of work-based assessors (WBAs) within our hospital is increasing awareness, but has it reduced injuries within our area?
The Cognitive Behavioral Physical Activity Questionnaire: A study of validity and reliability<p>Bilişsel Davranışçı Fiziksel Aktivite Ölçeği: Geçerlik ve güvenirlik çalışması
Authors: Eskiler Ersin , Küçükibiş Fatih , Gülle Mahmut , Soyer Fikret 
Published: May 2016

In recent years, the obesity affected the public health significantly in a negative way in Turkey as in the world and this situation was known to be increased steadily especially among children and adolescents. Although there were different views on what caused the obesity, irregular and / or improper diet and the lack of physical activity was defined as two basic reasons for it. In this context, in order to put into practice the effective practices related to be directed or increased participation for physical activity, understanding and determining the attitudes and behaviors of young people towards regular exercise participation was so crucial. This research had been carried out to adapt Cognitive Behavioral Physical Activity Questionnaire (CBPAQ) to Turkish. 590 students (297 male/293 female), who are 13-17 years and living in Bursa, participated to the research. The sample was determined by easy sampling method. In analyzing the data, descriptive analysis, principal component factor analysis (EFA) and confirmatory factor analysis (CFA) was used. According to the results, 15 items and 5-dimensional structure located in its original form was determined to be statistically verified. It could be concluded that the Cognitive Behavioral Physical Activity Scale for the respective sample could be used as a reliable and valid measurement tool. ÖzetSon yıllarda Dünya genelinde olduğu gibi Türkiye’de de obezite önemli boyutlarda toplum sağlığını olumsuz yönde etkilemekte ve bu durumun özellikle çocuk ve gençler arasında giderek artış gösterdiği bilinmektedir. Obeziteye, nelerin neden olduğu konusunda farklı görüşler olmakla birlikte, en temel iki nedenin; düzensiz ve/veya yanlış beslenme ile fiziksel aktivite yetersizliği olduğu ifade edilmektedir. Bu bağlamda gençlerin fiziksel aktiviteye yönlendirilmesi ya da katılımlarının arttırılmasına ilişkin etkin uygulamaların hayata geçirilebilmesi için, öncelikle gençlerin düzenli egzersiz katılımına yönelik tutum ve davranışlarını belirlemek ve anlamak hayati bir öneme sahiptir. Açıklamalar ışığında, bu araştırma; Bilişsel Davranışçı Fiziksel Aktivite Ölçeğini (Cognitive Behavioral Physical Activity Questionnaire; CBPAQ) Türkçe’ ye ve Türk popülasyonuna uyarlanmak amacıyla gerçekleştirilmiştir. Araştırmaya Bursa ilinde öğrenim gören 13-17 yaş aralığında 590 (297 erkek ve 293 kadın) kişi katılmış ve örnek kütle kolayda örnekleme yöntemi ile belirlenmiştir. Verilerin analizinde, betimsel analizler, temel bileşenler faktör analizi (AFA) ve doğrulayıcı faktör analizi (DFA) kullanılmıştır. Bulgular ışığında ölçeğin orijinal formunda yer alan 15 ifade ve 5 boyutlu yapının istatistiksel olarak doğrulandığı belirlenmiştir. Nihai olarak, Bilişsel Davranışçı Fiziksel Aktivite Ölçeği’nin ilgili örneklem grubu için geçerli ve güvenilir bir ölçüm aracı olarak kullanılabileceği sonucuna ulaşılmıştır.
Impactos geomorfológicos del terremoto de Limón (1991; ms=7.5) y consideraciones para la prevención de riesgos asociados en Costa Rica
Authors: Quesada-Román Adolfo 
Published: May 2016

El Terremoto de Limón (Ms = 7.5) se presentó el 22 de abril de 1991 y tuvo su epicentro en las coordenadas 9.685 N y -83 .073 W. El objetivo de esta investigación fue estudiar la relación de los procesos detonados por el sismo en el modelado del relieve en el área más afectada: la Cuenca Limón Sur. La metodología consistió en una revisión bibliográfica de los estudios técnicos así como científicos realizados sobre el desastre y el análisis de sus implicaciones geomorfológicas. Los efectos cosísmicos fueron el levantamiento tectónico, la licuefacción, deslizamientos, inundaciones y un aumento de la carga de sedimentos en el sistema fluvial. Este suceso fue una importante enseñanza para Costa Rica en términos de gestión de una emergencia de gran magnitud, además cimentó la base de incipientes medidas de prevención y mitigación del riesgo de desastres. ABSTRACT The Limon Earthquake (Ms = 7.5) occurred on April 22, 1991 with its epicenter located at coordinates 9,685 N and -83,073 W. The objective of this research was to study the relationship of the processes triggered by the earthquake on modeling the topography of the most affected area -the Southern Limon Basin. The methodology consisted on a literature review regarding the technical and scientific studies conducted about the disaster and the analysis of its geomorphological implications. The coseismic effects that occurred were the tectonic uplift, liquefaction, landslides,floods, and an increase of the fluvial system´s sediment load. This event was a great lesson for Costa Rica in terms of managing a major emergency, and it also helped building the foundation for emerging prevention measures and disaster risk reduction.
LAS POLÍTICAS PÚBLICAS CON PERSPECTIVA DE DERECHOS HUMANOS EN EL GIRO A LA IZQUIERDA. DE LA RUPTURA A LA SEGUNDA VUELTA INSTITUCIONAL EN VENEZUELA Y ECUADOR
Authors: Espinosa Díaz Claudia , Vázquez Valencia Daniel 
Published: May 2016

Hay tres procesos políticos que interactúan en algunos países de América Latina: el giro a la izquierda, la generación de movimientos constituyentes impulsados por dichos gobiernos, y un cada vez más relevante papel de los derechos humanos (DH) en la formulación de política pública (PP). Daremos cuenta de la convergencia de estos procesos situándonos en el último: la PP con perspectiva de DH (PPDH). La constitucionalización de los derechos humanos es un tema extensamente trabajado; sin embargo, la vinculación de este con la política pública es un ámbito de análisis relativamente nuevo, aunque fundamental para entender las brechas entre el cumplimiento y el ejercicio de los derechos humanos. Nos preguntamos: ¿cuál es la relación entre las constituciones emitidas por los gobiernos del giro a la izquierda y la formulación de PPDH? Se esperaría que el papel que tomaron los DH en las nuevas constituciones tuviera un impacto sostenido en la formulación de la PP; no obstante, esto no es necesariamente así. Si bien hay interacción entre las constituciones y las PP, hay dos aspectos interesantes por subrayar: el proceso de resignificación, en el caso ecuatoriano, y la segunda vuelta institucional, en el caso venezolano. Public policies with a human rights perspective in the shift to the left. From rupture to the second round in Venezuela and Ecuador Abstract There are three processes that interact in certain countries in Latin America: the shift to the left, movements to develop new constitutions driven by left wing governments , and the increasingly relevant role played by human rights in the development of public policy. We will make evident these interactions by analyzing this last point: public policy with a human rights perspective (PPHR). The inclusion of human rights in constitutions is something that has been thoroughly analyzed; yet the link of this inclusion with pubic policy is an area that is relatively new despite it being key in understanding the gaps between the fulfillment and enjoyment of human rights. We ask: what is the relationship between constitutions issued by left wing governments and the development of PPHR? One would expect that the role played by human rights in new constitutions would have a sustained impact in the development of PP. This is not necessarily the case: although there is interaction between constitutions and PP, there are two interesting aspects to highlight: the rebranding in the case of Ecuador and the second round in the case of Venezuela.
Seleção de cultivares de cana-de-açúcar para a Zona da Mata Norte de Pernambuco II: Meio de safra
Authors: Albuquerque A. P. C. , Bastos G. Q. , Dutra Filho J. A. , Souto L. S. , Medeiros A. C. , Simões Neto D. E. 
Published: May 2016

<p>Sendo os cultivares melhorados a base de sustentação e desenvolvimento do setor sucroeneregético no Brasil, objetivou-se com este trabalho avaliar o desempenho agroindustrial de 26 cultivares de cana-de-açúcar na microrregião canavieira da Mata Norte de Pernambuco. O experimento foi conduzido na área agrícola da Usina Olho D’água, onde foi utilizado o delineamento experimental em blocos casualizados com quatro repetições. As variáveis analisadas foram: toneladas de pol por hectare, toneladas de cana por hectare, fibra, pol % corrigida, pureza, teor de sólidos solúveis e açúcar total recuperável. Realizou-se a análise de variância conjunta dos experimentos e estimativa de parâmetros genéticos, as médias foram agrupadas pelo teste de Scott e Knott ao nível de 5% de probabilidade. Realizou-se ainda a rentabilidade econômica bruta de cada cultivar. Constatou-se que a seleção de cultivares superiores deve ser baseada nas variáveis TPH e TCH. Como opções de cultivo comercial para a segunda época de colheita destacam-se como mais produtivas, RB93509, SP81-3250 e RB75126.</p><p align="center"><strong><em>Selection of sugarcane cultivars to the North Forest Zone of Pernambuco II: crop Medium</em></strong></p><p><strong>Abstract: </strong>Improved cultivars are support base and development of energétic and alcohol sector in Brazil, aimed with this work was to evaluate the agroindustrial performance of 26 sugarcane cultivars in the microrregion da Mata Norte of Pernambuco. The experiment was conducted in the agricultural area of the sugarmill Olho d'gua, which was used a randomized block with four replications. The variables analyzed were tons of pol per hectare, sugarcane tons per hectare, fiber, corrected pol%, purity, soluble solids content and total recoverable sugar. Were conducted the variance analysis and estimation of genetic parameters, the averages were grouped by the Scott and Knott test at 5% probability. It was held still gross economic profitability of each cultivar. The selection of superior cultivars should be based on TPH and TCH variables. As commercial cultivation options for the second harvest season stand out as more productive, RB93509, SP81-3250 e RB75126.<strong></strong></p>
Macrophages Play a Key Role in the Obesity‐Induced Periodontal Innate Immune Dysfunction via Nucleotide‐Binding Oligomerization Domain‐Like Receptor Protein 3 Pathway
Authors: Huang Xin , Yu Ting , Ma Chanjuan , Wang Yixiong , Xie Baoyi , Xuan Dongying , Zhang Jincai 
Published: May 2016

Background: Obesity is associated with infiltration of macrophages into adipose tissue. However, effects of obesity on macrophage infiltration and activation in periodontal tissues with periodontitis are still to be elucidated.Methods: A diet‐induced obesity 16‐week mouse model was constructed, and periodontitis was induced by periodontal ligation for 10 days. The model consisted of periodontitis (P) and control (C) groups, with high fat (HF) and normal (N) diet conditions. Bone loss (BL) was analyzed by microcomputed tomography. In periodontal tissues, immunohistochemical staining and quantitative polymerase chain reaction (qPCR) detected expressions of: 1) nucleotide‐binding oligomerization domain‐like receptor protein 3 (NLRP3) pathway; 2) macrophage‐specific marker (F4/80); and 3) macrophage chemotactic protein 1 (MCP1). Bone marrow‐derived macrophages (BMDMs) from the mouse model were stimulated by Porphyromonas gingivalis lipopolysaccharide (LPS) in vitro (NC/NC + LPS: BMDMs from NC group without/with LPS stimulation; HFC/HFC + LPS: BMDMs from HFC group without/with LPS stimulation). Expressions of NLRP3 pathway in BMDMs were detected by immunocytochemical staining and qPCR.Results: BL increased significantly with periodontitis (NC versus NP; HFC versus HFP) and obesity (NP versus HFP). Expressions of NLRP3 pathway were significantly elevated in gingival tissues with periodontitis (NC versus NP; HFC versus HFP), but not with obesity (NC versus HFC; NP versus HFP). F4/80 and MCP1 expressions were significantly upregulated in gingival tissues with periodontitis (NC versus NP; HFC versus HFP) but significantly downregulated in the context of obesity (NP versus HFP). In vitro, NLRP3 pathway expressions were significantly upregulated in BMDMs after LPS stimulation (NC + LPS versus NC; HFC + LPS versus HFC), but significantly downregulated in HFC groups (HFC versus NC; HFC + LPS versus NC + LPS).Conclusion: Obesity may paralyze innate immune response of periodontium via attenuating infiltration and activation of macrophages and further aggravate periodontal disease.
Evaluation of Tissue Culture Seedlings for Their Genetic Fidelity and Virus Indexing in Sugarcane
Authors: D Adilakshmi , M Suresh , N Rajkumar , K Jayachandra , P Bebi 
Published: May 2016

Plant tissue culture technique is a powerful tool for rapid and large scale multiplication of virus free seed material. Clonal fidelity of the in vitro raised plants was carried out using RAPD. A total of fifteen primers were used for detecting polymorphism by RAPD analysis and the results revealed that all the tissue culture plants were grouped into one cluster and indicated that all the tissue culture developed plantlets are true-to-type. There are no somaclonal variations and are genetically identical with the mother plant. Virus indexing through ELISA indicated that the tissue culture developed seedlings does not contain the protein particles of ScMV and are free from the viral disease. The wells coated with leaf samples with suspected ScMV infection (97 A 85, C3) gave visual confirmation by yellow colour change, with OD 405 values of 0.526. As the reading is 2 times more than the negative control (OD 0.215) we can presume mild infection of mosaic in the test sample with lower titre of ScMV. All the ScMV +ve controls showed significant higher OD values of more than 2.515 confirming the earlier observations. Thus, viral detection using DAS-ELISA method can be used for detection and indexation in large scale sugarcane crop especially for in vitro regenerated plants with relatively cheaper cost and faster for supplying virus free seedlings to farming community in a large scale.
A Comparison between Integer and Fractional Order PD
μ
Controllers for Vibration Suppression
Authors: Birs Isabela R. , Muresan Cristina I. , Folea Silviu , Prodan Ovidiu 
Published: May 2016

Abstract
Along the years, unwanted vibrations in airplane wings have led to passenger discomfort. In this study, the airplane wing is modeled as a cantilever beam on which active vibration suppression is tested. The paper details the tuning of both integer and fractional order Proportional Derivative type controllers based on constraints imposed in the frequency domain. The controllers are experimentally validated and the results prove once more the superiority of the fractional order control approach.
Computation of the fifth Geometric-Arithmetic Index for Polycyclic Aromatic Hydrocarbons PAH
k
Authors: Alaeiyan Mehdi , Farahani Mohammad Reza , Jamil Muhammad Kamran 
Published: May 2016

Abstract
Let G be a simple connected graph. The geometric-arithmetic index of G is defined as

G

A

1

(
G
)

=

∑

u
ν
∈
E
(
G
)

2

d
(
u
)
d
(
ν
)

d
(
u
)
+
d
(
ν
)

$\begin{array}{}
G{A_1}\left( G \right) = {\sum\nolimits _{u\nu \in E(G)}}\frac{{2\sqrt {d(u)d(\nu)} }}{{d(u) + d(\nu)}}
\end{array}$

, where d(u) represents the degree of the vertex u in the graph G. Recently, Graovac defined the fifth version of geometric-arithmetic index of a graph G as

G

A

5

(
G
)

=

∑

u
ν
∈
E
(
G
)

2

S

ν

S

u

S

ν

+

S

u

$\begin{array}{}
G{A_5}\left( G \right) = {\sum\nolimits _{u\nu \in E(G)}}\frac{{2\sqrt {{S_\nu}{S_u}} }}{{{S_\nu} + {S_u}}}
\end{array}$

, where Su
is the sum of degrees of all neighbors of vertex u in the graph G. In this paper, we compute the fifth geometric arithmetic index of Polycyclic Aromatic Hydrocarbons (PAH
k
).
SURFACE BRIGHTNESS PROFILES OF DWARF GALAXIES. II. COLOR TRENDS AND MASS PROFILES
Authors: Herrmann Kimberly A. , Hunter Deidre A. , Elmegreen Bruce G. 
Published: May 2016

ABSTRACT
In this second paper of a series, we explore the B − V, U − B, and FUV−NUV radial color trends from a multi-wavelength sample of 141 dwarf disk galaxies. Like spirals, dwarf galaxies have three types of radial surface brightness profiles: (I) single exponential throughout the observed extent (the minority), (II) down-bending (the majority), and (III) up-bending. We find that the colors of (1) Type I dwarfs generally become redder with increasing radius, unlike spirals which have a blueing trend that flattens beyond ∼1.5 disk scale lengths, (2) Type II dwarfs come in six different “flavors,” one of which mimics the “U” shape of spirals, and (3) Type III dwarfs have a stretched “S” shape where the central colors are flattish, become steeply redder toward the surface brightness break, then remain roughly constant beyond, which is similar to spiral Type III color profiles, but without the central outward bluing. Faint (−9 > M

B
> −14) Type II dwarfs tend to have continuously red or “U” shaped colors and steeper color slopes than bright (−14 > M

B
> −19) Type II dwarfs, which additionally have colors that become bluer or remain constant with increasing radius. Sm dwarfs and BCDs tend to have at least some blue and red radial color trend, respectively. Additionally, we determine stellar surface mass density (Σ) profiles and use them to show that the break in Σ generally remains in Type II dwarfs (unlike Type II spirals) but generally disappears in Type III dwarfs (unlike Type III spirals). Moreover, the break in Σ is strong, intermediate, and weak in faint dwarfs, bright dwarfs, and spirals, respectively, indicating that Σ may straighten with increasing galaxy mass. Finally, the average stellar surface mass density at the surface brightness break is roughly 1−2 M
⊙ pc−2 for Type II dwarfs but higher at 5.9 M
⊙ pc−2 or 27 M
⊙ pc−2 for Type III BCDs and dIms, respectively.
A TEMPORAL ANALYSIS INDICATES A MILDLY RELATIVISTIC COMPACT JET IN GRS 1915+105
Authors: Punsly Brian , Rodriguez Jérôme 
Published: May 2016

ABSTRACT
Most of our knowledge of the radio morphology and kinematics of X-ray binary partially synchrotron self-absorbed compact jets (hereafter, compact jets) is based on the observations of GRS 1915+105, which has the most prominent compact jet. Yet, the compact jet bulk velocity, v, is poorly constrained in the literature,

. In spite of this uncertainty, compact jets are often unified with relativistic jets in active galactic nuclei. We estimated v as part of a temporal analysis of GRS 1915+105 jets in “high plateau states” (HPS). We define HPS as a state showing a hard X-ray spectrum and low level of long-term (

s) X-ray activity associated with 15 GHz flux density

mJy for

consecutive days. The radio emission is associated with compact jet emission. Two HPS were monitored at 15 GHz during their termination with e-folding times of 3.8 and 8.6 hr. We combine this timescale with the scale of the spatial variation of the linear source of a Very Large Baseline Array image preceding the fade of one of these HPS in order to estimate the jet speed. Our assumption that the reduction in radio emissivity propagates as an approximate discontinuity down the HPS jet (leaving a weak jet in its wake) indicates

. This agrees closely with the only other existing v estimates that are derived directly from radio images, jet asymmetry produced by Doppler enhancement.