bluuebunny/crossref_metadata_2025_split huggingface dataset:
Raw sequence to target gene prediction: An integrated inference pipeline for ChIP-seq and RNA-seq datasets
Authors: Wani Nisar , Raza Khalid 
Published: November 2017

AbstractGene expression patterns determine the manner whereby organisms regulate various cellular processes and therefore their organ functions.These patterns do not emerge on their own, but as a result of diverse regulatory factors such as, DNA binding proteins known as transcription factors (TF), chromatin structure and various other environmental factors. TFs play a pivotal role in gene regulation by binding to different locations on the genome and influencing the expression of their target genes. Therefore, predicting target genes and their regulation becomes an important task for understanding mechanisms that control cellular processes governing both healthy and diseased cells.In this paper, we propose an integrated inference pipeline for predicting target genes and their regulatory effects for a specific TF using next-generation data analysis tools.
What are the most influencing factors in reconstructing a reliable transcriptome assembly?
Authors: Ghaffari Noushin , Abante Jordi , Singh Raminder , Blood Philip D. , Pipes Lenore , Mason Christopher , Johnson Charles D. 
Published: November 2017

AbstractReconstructing the genome and transcriptome for a new or extant species are essential steps in expanding our understanding of the organism’s active RNA landscape and gene regulatory dynamics, as well as for developing therapeutic targets to fight disease. The advancement of sequencing technologies has paved the way to generate high-quality draft transcriptomes. With many possible approaches available to accomplish this task, there is a need for a closer investigation of the factors that influence the quality of the results. We carried out an extensive survey of variety of elements that are important in transcriptome assembly. We utilized the human RNA-Seq data from the Sequencing Quality Control Consortium (SEQC) as a well-characterized and comprehensive resource with an available, well-studied human reference genome. Our results indicate that the quality of the library construction significantly impacts the quality of the assembly. Higher coverage of the genome is not as important as the quality of the input RNA-Seq data. Thus, once a certain coverage is attained, the quality of the assembly is mainly dependent on the base-calling accuracy of the input sequencing reads; and it is important to avoid saturating the assembler with extra coverage.
Hyperacuity Bayesian methods to enhance temporal resolution of two-photon recording of the complex spikes in the cerebellar Purkinje cells
Authors: Hoang Huu , Sato Masa-aki , Kawato Mitsuo , Toyama Keisuke 
Published: November 2017

AbstractTwo-photon imaging is a major recording technique in neuroscience but its low sampling rate imposes a severe limit of elucidating high temporal profiles of neuronal dynamics. Here we developed two hyperacuity Bayesian algorithms to improve spike detection and spike time precision, minimizing the estimation error supervised by the ground-truth given as the electrical spike signals. The benchmark showed that our algorithms outperformed other unsupervised algorithms maximizing the likelihood of the estimates for both experimental and simulation data. We argue that the supervised algorithms are useful tools to improve spike estimation of two-photon recording in case ground truth signals are available.
The para hydroxy acetanilide and acetanilide mixture for the protection from corrosion of alloyed zinc
Authors: Zouied Daoiya , Zouaoui Emna , Medjram Mohamed Salah , Chikha Olfa , Dob Karima 
Published: November 2017

PurposeCorrosion and corrosion inhibition of alloyed zinc electrode were investigated in neutral chloride solution using electrochemical techniques. The purpose of this study is to study the corrosion inhibition of acetanilide and para hydroxy acetanilide as organics inhibitors for corrosion control of alloyed zinc electrode in NaCl 3 per cent solution.Design/methodology/approachA volt lab PGZ 301, assembled using alloyed zinc working electrode, a platinum counter electrode and a saturated calomel electrode as the reference electrode, was used in the experiment. This research was conducted using potentiodynamic polarization and electrochemical impedance spectroscopy techniques.FindingsAcetanilide, para hydroxy acetanilide and their mixture provided inhibitions efficiencies of 88 per cent at 40 ppm, 87 per cent with 80 ppm and 99.86 per cent with (40 ppm AC + 80 ppm PHA), respectively. The study also discusses the corrosion inhibition mechanism of the protective layers. The adsorption of acetanilide and para hydroxy acetanilide on metal surface obeyed Langmuir’s adsorption isotherm. Polarization measurements showed that the acetanilide and the para hydroxy acetanilide, and their mixture acted as cathodic inhibitors in NaCl solution, and the inhibitor molecules followed physical adsorption on the surface of alloyed zinc.Originality/valueThe other new inhibitors which are very efficient inhibitors and to be applied in the field of prevention and control against corrosion.
A review of contributing parameters in corrosion of oil and gas wells
Authors: Mobaraki Nejad Ali 
Published: November 2017

Purpose
This paper aims to provide an insight into the main parameters that govern corrosion mechanisms in production tubing of oil and gas wells.

Design/methodology/approach
Corrosion has been an old concern for the oil industry. None of the three major sectors of the oil industry, namely, upstream, midstream and downstream, are immune of corrosion attacks. However, the upstream sector (oil and gas production facilities) is more vulnerable to corrosion because of its extreme conditions such as high temperature and pressure, multiphase flow, complicated water chemistry, presence of acidic gases, etc. This paper is a general review of the influence of such parameters on corrosion mechanisms of oil and gas wells.

Findings
In recent years, many technical papers have been published in this area. However, none of them provide a general review of the all contributing parameters on corrosion under field conditions.

Originality value
Modeling and corrosion mitigating processes under downhole conditions require a thorough understanding of the influencing parameters. This paper aims to provide an insight into the main parameters that govern corrosion mechanisms in production tubing of oil and gas wells.
Electrochemical study on the corrosion rate of X52 steel exposed to different soils
Authors: Quej-Ake L.M. , Contreras A. 
Published: November 2017

PurposeThe purpose of this work is to study the corrosion rate of X52 pipeline steel exposed to three types of soils collected in Campeche State in México. The electrochemical evaluation for X52 steel exposed to soils ranging from saturated soil until dry conditions was carried out for a period of 21 days. Owing to its versatility to study the steel corrosion process exposed to different types of soils, electrochemical impedance spectroscopy (EIS), potentiodynamic polarization and cyclic voltammetry tests were performed. Additionally, optical and electronic microscopy observations of the steel surface were carried out.Design/methodology/approachElectrochemical cell arrangement was described elsewhere (Quej-Ake et al., 2014). Owing to soil being an electrolytic system with high resistivity and impedance, all electrodes were placed as close as possible, and iR-drop compensation was taken into account using two rods of graphite as an auxiliary electrode. In addition, the conductivity of the soil (Rs) obtained from EIS was used to correct the potential of the working electrode according to iR-drop, and an analysis of ohmic drop from the polarization curves was carried out.FindingsSaturated conditions of the three soils were initially considered as the most corrosive conditions for X52 steel surface. Finally, 21 days of immersion time was taken into account as the more drastic condition. So, according to results, X52 steel exposed to beach sand was more susceptible to the corrosion process (0.092 mm/year). iR corrected was negligible at low over-potentials region in saturated soils, which is inside the linear region of Tafel or the activation region. In addition, high cathodic peak potential value obtained from cyclic voltammetry for X52 steel exposed to saturated soil may be attributed to hydrogen evolution reaction and neutral pH.Research limitations/implicationsThe paper has implications for research. It bridges the gap between theory and practice.Originality/valueCyclic voltammetry is a really important tool for the electrochemical analysis of the pipeline steel surface exposed to saturated soils, but is not adequate for analysis of steel exposed to dried soils. In addition, the physicochemical results show that fissures, voids and extra-oxygen presence could also affect the electrochemical responses obtained for X52 steel exposed to soils.
Continuous improvement methodologies and practices in hospitality and tourism
Authors: Farrington Thomas , Antony Jiju , O’Gorman Kevin D. 
Published: November 2017

Purpose
This paper aims to present a systematic literature review (SLR) of continuous improvement (CI) research in the hospitality and tourism management (HTM) literature. The paper also notes trends, parallels, inconsistencies and opportunities towards a clearer understanding of current scholarship.

Design/methodology/approach
This SLR finds a dearth of research in the field. After parameter expansion and exclusions, 35 papers across 11 journals are reviewed.

Findings
Studies of CI methodologies and practices are published infrequently, tending to focus on total quality management in European contexts. Despite the guiding customer-centric principles of CI methodologies, studies focus on improving internal processes rather than the service encounter.

Research limitations/implications
The review is guided by sections of the ABS 2015 list, which excludes some journals. Books, conference papers and trade magazine articles are not reviewed.

Practical implications
This paper identifies clear needs for CI research with a specific hospitality management focus, the development of CI toolkits and curricula for hospitality managers. The development and deployment of CI methodologies and practices in HTM literature and industry should lead to long-term service improvements.

Originality/value
This study asserts the need for further context-specific, practice-led research into the refinement and long-term utility of CI methodologies and practices, towards demonstration of significant bottom-line industry impact. The paper also offers a clear SLR methodology and a definition for CI in hospitality.
Knowledge-advanced innovative behaviour: a hospitality service perspective
Authors: Edghiem Farag , Mouzughi Yusra 
Published: November 2017

Purpose
The purpose of this paper is to explore the nature and implications of knowledge advanced through service employees’ innovative behaviour and leading to initiating innovation within the hotel service subsector.

Design/methodology/approach
A case study research method was applied to achieve the research objectives, which investigated two hotel properties resembling two personal–interactive service systems. In total, 52 semi-structured interviews were conducted along with other qualitative research methods, including the direct observation of employees, review of management archives/literature and the assessment of “micro cases”.

Findings
The research outcome highlights the role of knowledge as supplementary to the interlinked process of idea generation and development. A novel classification of two types of knowledge is revealed as pre-encounter and encounter-dependent knowledge, implicating four patterns of service employees’ innovative behaviour.

Practical implications
This paper recommends practical measures to nurture service employees’ innovative behaviour, leading to innovation.

Originality/value
This study contributes to service innovation research by providing an in-depth assessment at the micro level, overlooked to date, of the nature of knowledge and the service employees’ role in initiating innovation within the hotel service subsector.
Learning from press releases: implications for hospitality innovation
Authors: Zach Florian J. , Krizaj Dejan , McTier Brian 
Published: November 2017

Purpose
The purpose of this study is to test the usefulness of the literature-based innovation output (LBIO) approach to identify innovation types from press releases of hospitality firms and to evaluate if the typology captures the effect of innovation on firm value.

Design/methodology/approach
The LBIO approach was applied to three years of press releases from two publicly traded lodging firms in the USA announcing innovations. A database of lodging and innovation relevant terms was compiled. Starting with classifications found in the innovation literature, the researchers coded each announcement. Coded announcements were clustered into innovation types using pairwise similarity analysis. Event study analysis assessed the efficacy of the overall method to find types that were useful to measure the impact on firm value from the company’s adoption of an innovation.

Findings
Cluster analysis identified four lodging innovation types: property and location, marketing, strategic development and guest experiences. These types corresponded closely with the innovation classification suggested by the Oslo Manual. The event study found that the typology was useful in determining the market value effects of an innovation.

Research limitations/implications
This study focused on innovation; future studies might test other organizational factors. The study uses data from two large, publicly traded hospitality firms and may not extend to smaller, privately held businesses. A key implication is that human coding is sufficient to identify innovation types that correspond closely with existing classifications and affect firm value.

Originality value
This study successful learns from hospitality press releases to identify a hospitality innovation typology and tests type impact on firm value.
Brand strategies in social media in hospitality and tourism
Authors: Moro Sérgio , Rita Paulo 
Published: November 2017

Purpose
This paper aims to present an automated literature analysis to unveil the drivers for incorporating social media in tourism and hospitality brand strategies.

Design/methodology/approach
To gather relevant literature, Google Scholar was queried with “brand”/“branding” and “social media” for articles in ten top-ranked tourism and hospitality journals, resulting in a total of 479 collected articles. The methodology adopted for the analysis is based on text mining and topic modeling procedures. The topics discovered are characterized by terms belonging to a dictionary previously compiled and provide a segmentation of the articles in coherent sets of the literature.

Findings
Most of the 213 articles that encompass a strong relation between social media and branding are mentioning mainly brand building stages. A large research gap was found in hospitality and tourism considering that, besides advertising, no topic was discovered related to known brand strategies such as co-branding or franchising.

Practical implications
The present analysis concludes that specialized tourism and hospitality literature needs to keep pace with research that is being conducted on a wide range of industries to assess the influence of social media.

Originality/value
The automated analysis approach used has no precedent in tourism and hospitality research. By including an innovative topical concept map, it led to identifying and summarizing the topics, providing a clear picture on the findings. This study calls for research by specialized tourism and hospitality publications, eventually leading to special issues on this vibrant subject.
Disability, hospitality and the new sharing economy
Authors: Boxall Kathy , Nyanjom Julie , Slaven Janine 
Published: November 2017

Purpose
This paper aims to explore the place of disabled guests in the new world of hotel and holiday accommodation shaped by the sharing economy.

Design/methodology/approach
The paper uses Levitas’s (2013) Utopia as Method as a methodological tool to develop the hypothetical future scenarios, which are used to explore the place of disabled guests in peer-to-peer holiday accommodation.

Findings
Analysis of the hypothetical scenarios suggests that without state intervention, the place of disabled guests in both traditional hotels and peer-to-peer holiday accommodation is far from secure.

Research limitations/implications
This is a new area and the authors’ discussion is therefore tentative in its intent.

Practical implications
Planners and policymakers should consult with, and take account of, the needs of disabled people and other socially excluded groups when regulating shared economy enterprises. It may be helpful to put in place broader legislation for social inclusion rather than regulate peer-to-peer platforms. Any recourse to markets as a means of resolving access issues needs also to acknowledge the limited power of socially excluded groups within both traditional and sharing economy markets.

Social implications
The hypothetical scenarios discussed within this paper offer planners, policymakers and tourism stakeholders opportunities to think through the access and inclusion needs of disabled guests in the shared economy sector.

Originality/value
The paper extends discussion of hospitality and disability access to include shared economy approaches and the place of disabled guests in the new world of holiday accommodation shaped by the sharing economy.
Unmasking the contributing factors of entrepreneurial activities among men and women in Ghana
Authors: Quartey Peter , Danquah Michael , Owusu George , Iddrisu Abdul Malik 
Published: November 2017

Purpose
Using the 2010 Global Entrepreneurship Monitor (GEM) survey data, the purpose of this paper is to investigate the contributing factors of entrepreneurial propensity among males and females in Ghana.

Design/methodology/approach
Using a measure of entrepreneurial propensity that takes into account individuals who are involved in starting a new business (nascent entrepreneurs) as a dependent variable and socio-demographic characteristics, and perceptual variables as explanatory variables, the study adopts robust empirical estimation techniques to examine how these variables influence the probability of starting a new business among men and women in Ghana.

Findings
The probability of being a male nascent entrepreneur is significantly dependent upon a wide range of factors including demographic, economic, perceptual and contextual elements, albeit with important variations across gender. An individuals’ subjective assessment of fear of failure in starting a business and of having the requisite entrepreneurial capabilities; the age of the individual; gender of the individual; work status and contextual factors matters for entrepreneurial propensity in Ghana. However, important differences exist in the drivers of entrepreneurial propensity for males and females with females’ entrepreneurship attributed largely to conditions of necessity relative to their male counterparts.

Originality/value
The main value of this paper is to use the GEM survey (which is nationally representative) for Ghana to analyze the contributing factors of the entrepreneurial propensity among men and women in Ghana.
The dynamics of Zakat donation experience among Muslims: a phenomenological inquiry
Authors: Kashif Muhammad , Faisal Jamal Khurrum , Abdur Rehman Mohsin 
Published: November 2017

Purpose
The charitable organizations must understand the forces influencing donor behaviours. This issue has been debated rigorously among researchers belonging to Western societies; however, the exploration of donation experience among non-Western academics is limited. This study aims to discover the phenomenon of Zakat donation experience – an Islamic religious act of charity donation performed among Muslims to enhance our understanding of religious consumption practices in a Muslim country setting of Pakistan.

Design/methodology/approach
The authors used phenomenological methodology to collect data from 35 donors via face-to-face interviews.

Findings
The informants advocate individuality while making Zakat donations and believe that an independent donation experience brings them with higher levels of happiness, intrinsic drive to spend more and spiritual comfort. The Zakat donation is regarded as a great source of self-protection against the realm of evil spirits which is entirely a new finding with respect to charity donations. The informants identified several reasons for not donating through charities which mainly include lack of trust and limited product mix offered by charitable organizations.

Practical implications
Based on the findings of this research, the authors suggest charitable organizations to ensure procedural transparency and emphasize on Zakat collection, distribution and utilization methods to attract more donors.

Originality/value
The study contributes generally to charity marketing knowledge and specifically to consumer decision-making of religious acts performed in Muslim societies. The phenomenological method of inquiry and its application to study an Islamic act of donation has limited discussion in previous studies, which is a unique product of this study.
Preventing the use of financial institutions for money laundering and the implications for financial privacy
Authors: Le Nguyen Chat 
Published: November 2017

Purpose
This paper aims to discuss the implication of money laundering preventive measures for financial privacy, with the focus on banking secrecy.

Design/methodology/approach
This paper, first, sets out the principal measures imposed on financial service providers to prevent money laundering. The interaction between the preventive measures and the desire for financial privacy is then discussed.

Findings
The adequate implementation of the preventive measures is highly important for financial institutions to be secure from money laundering. Nonetheless, the enforcement of these measures is becoming much more intrusive into financial privacy. In practice, financial privacy should be weighted fairly against the objectives of preventive measures.

Originality/value
This paper would be a good guidance on how to deal with tension and potential conflicts of interests between law enforcement authorities and financial service providers and between the protection of financial privacy and the objectives of the money laundering preventive measures.