bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revisiting the potential anti-obesity effects of kimchi and lactic acid bacteria isolated from kimchi: a lustrum of evidence
Authors: Sharma Anshul , Lee Hae-Jeung 
Published: October 2024

AbstractKimchi, a renowned and culturally significant Korean dish, has gained global recognition as a superfood due to its abundant nutritional content and positive impact on human health. The process of producing kimchi involves the fermentation of various vegetables using lactic acid bacteria (LAB). The primary genera of kimchi LAB encompass Lactobacillus, Lactococcus, Leuconostoc, Pediococcus, and Weissella. Impressively, kimchi comes in over 200 varieties with cruciferous vegetables as its main ingredients, complemented by a range of secondary ingredients that contribute to its nutritional and holistic health benefits. These secondary ingredients include salted fish, ginger, garlic, and red pepper powder. Due to its various functional properties, kimchi has attracted considerable interest. Kimchi has been extensively studied, and its recognized health benefits, including anti-oxidant, anti-tumor, anti-inflammatory, anti-microbial, anti-obesity, hepatoprotective, neuroprotection, anti-allergic, regulation of immunological responses, and many more, have been covered in many review papers. A current literature review regarding the anti-obesity properties of kimchi and kimchi LAB is currently lacking. Therefore, the present review has directed its attention towards the literature concerning the anti-obesity properties of kimchi and LAB derived from kimchi over the last five years.
Imaging manifestations and treatment efficacy of Granulomatous Lobular Mastitis: An analysis of 29 cases with internal and external traditional Chinese medicine approaches
Authors: Ning Qiuping , Zhang Zheng , Ren Hua , Fan Tiebing , Li Chunzhi 
Published: October 2024

Objectives: Using magnetic resonance imaging (MRI), we analysed the clinical manifestations of granulomatous lobular mastitis (GLM) before and after treatment with traditional Chinese medicine (TCM).
Methods: This was a retrospective study. Clinical manifestations and imaging features of patients with biopsy-proven GLM before and after treatment were retrospectively analysed from April 2021 to April 2023 at Xiyuan Hospital, China Academy of Chinese Medical Sciences.
Results: Among 29 women of childbearing age (mean age, 34.3±3.6 years), Compared to pre-therapy, the number of patients with lumps, ruptures, pain, and menstrual irregularities was significantly reduced (P < 0.05). The Chinese medicine staging demonstrated a transition from bulk to ulcerated (P=0.041). Pre- and post-treatment MRI changes included lesion number, distribution, maximal diameter, time-signal intensity curves (TIC), apparent diffusion coefficients (ADC), and BI-RADS categories 3 and 4a (all P＜0.05). Furthermore, substantial changes were seen in chest wall invasion, nipple discharge, increased feeding arteries, and skin edema (all P＜0.05).
Conclusion: Combining internal and external Traditional Chinese Medicine (TCM) therapy proved successful for GLM. A reliable assessment of therapy efficacy is provided by MRI examination of lesion changes before and after treatment.
doi: https://doi.org/10.12669/pjms.40.10.8981
How to cite this: Ning Q, Zhang Z, Ren H, Fan T, Li C. Imaging manifestations and treatment efficacy of Granulomatous Lobular Mastitis: An analysis of 29 cases with internal and external traditional Chinese medicine approaches. Pak J Med Sci. 2024;40(10):2410-2415. doi: https://doi.org/10.12669/pjms.40.10.8981
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Na pograniczu chemii, biologii i fizyki – rozwój nauk. Tom 4
Authors: Szłyk Edward 
Published: October 2024

Dear Readers,	We present to you the fourth volume of the monograph "Na pograniczu chemii, biologii i fizyki – rozwój nauk” ("On the border of chemistry, biology and physics – development of sciences") containing several articles sent for printing by participants of the 15th Copernican Doctoral Seminar, which returned to its traditional form after the turmoil related to the pandemic. We are celebrating a small anniversary of a conference in the form of a seminar, which is the most beneficial for PhD students. Thus, the conference has a doctoral character and stands out from other similar meetings with its interdisciplinary nature. This year's monograph presents the results of work in the following disciplines: biology, chemistry, physics, food sciences and material sciences. The subject of the monograph covers issues of modern science related to progress in areas important for society (energy, global warming, new materials) in an interdisciplinary way, i.e. in accordance with the assumptions of the Copernican Doctoral Seminar. During the 15th CDS, the issues of the Priority Research Areas of the NCU were discussed, such as: astrophysics and astrochemistry; towards personalised medicine, which were discussed in separate scientific sections of the 15th CDS, contributing to the improvement of the scientific quality of the seminar. The published articles bring new knowledge to the field of exact and natural sciences, and the reader will find valuable cognitive and methodological data for the development of research towards his or her doctorate.
Asymmetric Naïveté: Beliefs About Self-Control
Authors: Fedyk Anastassia 
Published: October 2024

Do individuals anticipate time inconsistency in others? This paper jointly investigates beliefs about one’s own and others’ present bias. In an online laboratory experiment, participants engaged in a real-effort task display little awareness of their own present bias but anticipate present bias in others. Structurally, I estimate a present bias parameter [Formula: see text] of 0.82. Participants perceive others’ [Formula: see text] to be 0.87, indicating substantial sophistication, contrasted with 1.03 for themselves, indicating full naïveté. At the individual level, asymmetric naïveté correlates with overoptimism regarding one’s own versus others’ task enjoyment and time availability. The wedge in beliefs about present bias can inform equilibrium outcomes in a number of collaborative, competitive, and hierarchical settings, including teams in the workplace, management practices such as deadlines and tournament incentive schemes, and household consumption decisions. This paper was accepted by Yan Chen, behavioral economics and decision analysis. Funding: Financial support from the Laboratory for Economic Applications and Policy (Harvard University); Pershing Square Venture Fund for Research on the Foundations of Human Behavior (Harvard University); Harvard Business School (PhD Research Budget); and the Russell Sage Foundation (Small Research Grant) is gratefully acknowledged. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/mnsc.2021.01780 .
psk1 virulence gene-induced pulmonary and systemic tuberculosis in a young woman with normal immune function: A case report
Authors: Wu Fan , Yang Bin , Xiao Yan , Ren Li-Li , Chen Hong-Yi , Hu Xin-Lan , Pan Yan-Yu , Chen Yu-Sheng , Li Hong-Ru 
Published: October 2024

BACKGROUND
Tuberculosis is a chronic infectious disease and an important public health problem. Despite progress in controlling tuberculosis, the incidence of tuberculosis in China is still very high, with 895000 new cases annually. This case report describes the investigation of a case of severe disseminated tuberculosis in a young adult with normal immune function, conducted to ascertain why a Mycobacterium tuberculosis (M. tuberculosis ) strain caused such severe disease.
CASE SUMMARY
A previously healthy 28-year-old woman presented to our hospital with a 1-month history of fever and fatigue. She was diagnosed with severe disseminated pulmonary tuberculosis, spinal tuberculosis with paravertebral abscesses, and tuberculous meningitis. M. tuberculosis was isolated from bronchoalveolar lavage fluid. She was treated with standard antituberculous therapy and underwent debridement, bone graft, and internal fixation surgery for spinal tuberculosis. She responded to therapy and regained her ability to walk following the surgery. We analysed the whole-genome sequence of the strain and designated it BLM-A21. Additional M. tuberculosis genomes were selected from the Virulence Factor Database (http://www.mgc.ac.cn/cgi-bin/VFs/genus.cgi?Genus=Mycobacterium ) for comparison. An evolutionary tree of the BLM-A21 strain was built using PhyML maximum likelihood software. Further gene analysis revealed that, except for the pks1 gene, BLM-A21 had similar virulence genes to the CDC 1551 and H37Rv strains, which have lower dissemination.
CONCLUSION
We speculate that the pks1 virulence gene in BLM-A21 may be the key virulence gene responsible for the widespread dissemination of M. tuberculosis infection in this previously healthy adult with normal immune function.
Impact of observability period on the classification of COPD diagnosis timing among Medicare beneficiaries with lung cancer
Authors: Metwally Eman , Soppe Sarah E. , Lund Jennifer L. , Hinton Sharon Peacock , Thompson Caroline A. 
Published: October 2024

Background
Investigators often use claims data to estimate the diagnosis timing of chronic conditions. However, misclassification of chronic conditions is common due to variability in healthcare utilization and in claims history across patients.

Objective
We aimed to quantify the effect of various Medicare fee-for-service continuous enrollment period and lookback period (LBP) on misclassification of COPD and sample size.

Methods
A stepwise tutorial to classify COPD, based on its diagnosis timing relative to lung cancer diagnosis using the Surveillance Epidemiology and End Results cancer registry linked to Medicare insurance claims. We used 3 approaches varying the LBP and required continuous enrollment (i.e., observability) period between 1 to 5 years. Patients with lung cancer were classified based on their COPD related healthcare utilization into 3 groups: pre-existing COPD (diagnosis at least 3 months before lung cancer diagnosis), concurrent COPD (diagnosis during the -/+ 3months of lung cancer diagnosis), and non-COPD. Among those with 5 years of continuous enrollment, we estimated the sensitivity of the LBP to ascertain COPD diagnosis as the number of patients with pre-existing COPD using a shorter LBP divided by the number of patients with pre-existing COPD using a longer LBP.

Results
Extending the LBP from 1 to 5 years increased prevalence of pre-existing COPD from ~ 36% to 51%, decreased both concurrent COPD from ~ 34% to 23% and non-COPD from ~ 29% to 25%. There was minimal effect of extending the required continuous enrollment period beyond one year across various LBPs. In those with 5 years of continuous enrollment, sensitivity of COPD classification (95% CI) increased with longer LBP from 70.1% (69.7% to 70.4%) for one-year LBP to 100% for 5-years LBP.

Conclusion
The length of optimum LBP and continuous enrollment period depends on the context of the research question and the data generating mechanisms. Among Medicare beneficiaries, the best approach to identify diagnosis timing of COPD relative to lung cancer diagnosis is to use all available LBP with at least one year of required continuous enrollment.
Výzkumné pracoviště v oblasti sociologie mobility a psychologie dopravy
Authors: Schmeidler Karel 
Published: October 2024

Vědeckovýzkumná pracoviště jsou v jednotlivých zemích Evropské unie rozdělena nerovnoměrně, což působí nepříznivě jak na lokální zaměstnanost akademiků a absolventů vysokých škol, tak i na jejich inovativní přínos pro místní průmysl a ekonomický potenciál jednotlivých regionů. Evropská unie proto podporuje vznik a vývoj regionálních výzkumných center s cílem stimulovat konkurenceschopnost regionů v oblasti inovací a vědeckovýzkumných aktivit. Cílem projektu „Dopravní VaV centrum v Brně“ (dále Centrum) je vytvořit jedinečné výzkumné zázemí, které prostřednictvím svých laboratoří, vybavení a know-how bude poskytovat komplexní prostředí pro výzkum ve vybraných disciplínách dopravních aplikovaných věd a přispívat tak k optimálnímu rozvoji dopravního sektoru, nejen v daném regionu. Rozmanitost výzkumu Centra odpovídá potřebám a trendům současného dopravního výzkumu i potřebám praxe.
Lecturer’s Perceptions on the English Writing Competency in a Public University: A Focus Group Discussion
Authors: Sulaiman Fazillah , Bakar Erda Wati 
Published: October 2024

This study has been conducted to find out the lecturers’ perceptions of the students’ writing competency in a public university. The objective of the study is to explore the definition of a good piece of writing according to the lecturers and to know the strength and weakness of the students. In this public university, in all Faculties, major assignments are completed through writing, therefore students have to express themselves clearly and efficiently through their writing. This is a qualitative study using Focus Group Discussion with a total number of eight lecturers representing four main Faculties at the main campus. The Faculties are Laws, Economics and Management Sciences, Engineering and Human Sciences. Based on the Focus Group Discussion, the lecturers considered ideas and content, organisation, grammar and spelling as the three top important elements in writing. The lecturers considered the students as confident writers or ‘shameless’ writers which they believed is a significant element of being a good writer. The students have difficulties generating ideas. Thus, they will not be able to expand their writing further for their written assignments or projects. The lecturers added that lack of ideas is related to reading as well. Students who read more will be a better writer.
Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism
Authors: Krause Paulina N. , McGeorge Gabrielle , McPeek Jennifer L. , Khalid Sidra , Nelin Leif D. , Liu Yusen , Chen Bernadette 
Published: October 2024

AbstractA role for metabolically active adipose tissue in pulmonary hypertension (PH) pathogenesis is emerging. Alterations in cellular metabolism in metabolic syndrome are triggers of PH‐related vascular dysfunction. Metabolic reprogramming in proliferative pulmonary vascular cells causes a metabolic switch from oxidative phosphorylation to glycolysis. PDE3A and PDE3B subtypes in the regulation of metabolism in pulmonary artery smooth muscle cells (PASMC) are poorly understood. We previously found that PDE3A modulates the cellular energy sensor, AMPK, in human PASMC. We demonstrate that global Pde3a knockout mice have right ventricular (RV) hypertrophy, elevated RV systolic pressures, and metabolic dysfunction with elevated serum free fatty acids (FFA). Therefore, we sought to delineate Pde3a/Pde3b regulation of metabolic pathways in PASMC. We found that PASMC Pde3a deficiency, and to a lesser extent Pde3b deficiency, downregulates AMPK, CREB and PPARγ, and upregulates pyruvate kinase dehydrogenase expression, suggesting decreased oxidative phosphorylation. Interestingly, siRNA Pde3a knockdown in adipocytes led to elevated FFA secretion. Furthermore, PASMC exposed to siPDE3A‐transfected adipocyte media led to decreased α‐SMA, AMPK and CREB phosphorylation, and greater viable cell numbers compared to controls under the same conditions. These data demonstrate that deficiencies of Pde3a and Pde3b alter pathways that affect cell growth and metabolism in PASMC.
Export of Cultural Property from Ukraine: State Policy and the Challenges of War
Authors: Yanov Dmytro 
Published: October 2024

Abstract
The Russian invasion of Ukraine in 2022 inflicted severe damage on the country’s cultural heritage, triggering an upsurge in attempts to export cultural property across its borders. This paper deals with relevant issues related to the policy of Ukraine regarding the prevention of the export of cultural property abroad and the expertise of confiscated cultural property, as well as underscores the significance of enhancing state policy in this sphere in response to the challenges caused by Russian invasion. The notable increase in illegal attempts to export antiquities abroad requires a revision of the procedure for appointing and conducting the expertise of confiscated objects. This primarily applies to excessively prolonged periods of expertise, the lack of uniform rules applicable to all art experts regardless of their affiliations, and the ambiguous criteria defining “cultural property” in Ukrainian legislation. The paper proposes measures to resolve these difficulties, including introducing preliminary expertise at customs control, unifying the requirements for experts’ conclusions, and clarifying definitions in legislation.
Novel dynamics of the fractional KFG equation through the unified and unified solver schemes with stability and multistability analysis
Authors: Alam Noor , Ullah Mohammad Safi , Nofal Taher A. , Ahmed Hamdy M. , Ahmed Karim K. , AL-Nahhas Mahmoud A. 
Published: October 2024

Abstract
The nonlinear fractional Klein–Fock–Gordon (KFG) equation represents an advanced theoretical physics and applied mathematical tool that provides a more extraordinary framework for studying fields with complex and non-standard behaviors. Here, we aim to delve into the new wave profiles of this fractional KGF equation. Initially, this system is successfully converted into an ordinary differential equation (ODE) with the help of wave conversion, and the ODE is solved through the unified and unified solver techniques for the first time. In addition, the 3D and 2D plots of these solutions are drawn using a mathematical software package for different parameters with different values. Therefore, some unique waveforms can be found in these solutions. Moreover, stability and multistability analyses are prepared and shown graphically to confirm the converging limitations of appropriate parameters. This work will be practiced more effectively in future research on nonlinear partial differential models.
The Contribution of Community Informatics in Rural Communities to Development
Authors: Kirya Kenneth Erickson , Lutaaya Clement Nabutto 
Published: October 2024

Community informatics (CI) is a generic term used to refer to Information and Communication Technologies (ICTs) deployed in communities to meet community needs, simplify day-to-day tasks, close digital divides, among other benefits. In practice, it is about the use of information and ICTs in community development efforts to enable and empower community processes so as to achieve community social, economic, cultural and political goals. On the other hand, community development is the promotion of participative democracy, sustainable development, human rights, economic opportunity, equality and social justice, through the organization, education and empowerment of people within their communities. This paper established the contribution of community informatics to the development of rural communities with reference to Kaliro district as a case study area. Using participative case study design and mixed methods research approach, responses from 173 CI users and 33 district workers engaged through questionnaire survey and interviews respectively were analyzed and results were presented quantitatively in tables and qualitatively under themes for interpretation.
The study found out that CI contributed significantly to the district's social, economic, cultural, and political development. Towards social development, the CI promoted social connection and networking, ensured quick information flow, and fostered knowledge sharing. Towards economic development, they promoted trade and business, business and economic awareness, efficiency and effectiveness in service delivery, reduction in operational costs, job creation, income generation, and fostered new CI developments for businesses. Towards cultural development, they exported culture, promoted cultural awareness, tourism, and reinforced cultural freedom among the people of Kaliro district. In terms of political development, they had promoted government programs, human rights, provided government information, enabled civic education, eased follow-up on political developments, and fostered political stability in the district. Study findings showed that communities leverage CI and its infrastructure to keep up with information about government programs, health, environment, education, personal development, economic living, empowerment, and democracy, among others in a sense that triggers development. However, there is a general literature gap owing to the novelty of CI concept and the dearth in review evidence pointing out the contribution of CI to development of communities.
Keywords: Community informatics; Community development; ICT4D; Kaliro district.
Caracterização Sociodemográfica e Histórico de Condução de Pessoas Idosas Motoristas
Authors: Henrique dos Santos Lino Matheus , De Lima Guiotto Alisson , Santos Marques Felipe , Carazzolle Narciso Giovanna , Prota Cristina , Carlos Brech Guilherme , Castilho Alonso Angelica 
Published: October 2024

Objetivos: Analisar as dificuldades enfrentadas pelas pessoas idosas em relação à condução veicular, bem como avaliar a importância que atribuem a essa atividade. Métodos: Estudo transversal quantitativo avaliou 61 pessoas idosas motoristas utilizando dois questionários desenvolvidos pelos pesquisadores: 1) dados sociodemográficos, 2) questões relacionadas às dificuldades e à importância da condução para pessoas idosas. Resultados: A maioria dos participantes relatou apenas acidentes leves e não teve problemas significativos com condições climáticas, horários de direção ou estado das estradas. Os participantes usavam o carro para atividades diárias e lazer, dirigindo em média cerca de duas horas por dia. A prática de dirigir é vista como crucial para manter a autonomia e a conexão com a família, e a ideia de parar de dirigir é considerada um grande desafio. Conclusão: A capacidade de dirigir é vital para o bem-estar emocional e a qualidade de vida das pessoas idosas, mas o estudo também destaca os riscos associados à condução nessa idade, como a presença em acidentes leves durante a condução veicular. Portanto, é fundamental encontrar um equilíbrio entre manter a independência das pessoas idosas e garantir a segurança no trânsito.
How to Bridge Cognitive and Cultural Models of Religious Evolution
Authors: Jackson Joshua Conrad 
Published: October 2024

The scientific study of religion has roots in at least two traditions: a cognitive tradition which typically uses experimental studies to examine the proximal psychological processes underlying religious belief and ritual, and an anthropological tradition which uses historical and ethnographic data to examine how religious systems culturally evolve in social groups. In Religion Evolving, Purzycki and Sosis bridge both traditions and encourage a more integrated evolutionary science of religion. In this essay, I present three suggestions for how to make this science as ambitious and collaborative as possible. These suggestions are: (1) to move beyond straw man debates that pit byproduct models against functional models of religious evolution and acknowledge that these models are compatible from a dual inheritance perspective, (2) to evaluate functionalist claims with caution, recognizing how and when religion is adaptive vs. maladaptive for secular society, and (3) to avoid reductive definitions of religion and embrace religious pluralism. With these lessons in mind, we can usher in a bolder evolutionary science of religion that draws from both cognitive and cultural traditions.