bluuebunny/crossref_metadata_2025_split huggingface dataset:
Usefulness of an ultrathin endoscope in esophageal endoscopic submucosal dissection
Authors: Kikuchi Daisuke , Suzuki Yugo , Kawai Yusuke , Nomura Kosuke , Ochiai Yorinari , Hayasaka Junnosuke , Mitsunaga Yutaka , Okamura Takayuki , Odagiri Hiroyuki , Yamashita Satoshi , Matsui Akira , Tanaka Masami , Hoteya Shu 
Published: September 2024

Abstract
Background and study aims Endoscopic submucosal dissection (ESD)
is sometimes challenging because of stenosis and scarring. We examined the use of an ultrathin
endoscope for esophageal ESD, which is difficult using conventional endoscopes.
Patients and methods A designated transparent hood and ESD knife for ultrathin endoscopes have been developed and clinically introduced. Esophageal ESD was performed on 303 lesions in 220 patients in our hospital from February 2021 to February 2023. Of them, an ultrathin endoscope was used on 26 lesions in 23 cases. The safety and utility of an ultrathin endoscope in esophageal ESD were retrospectively verified.
Results All 26 lesions were resected en bloc, and serious complications such as perforation, massive bleeding, or pneumonia, were not observed. Lesions were found on the anal side of the stenosis and over the scarring in 38.6% (10/26) and 50% (13/26) of participants, respectively. Moreover, 46.2% of participants (12/26) had lesions on the cervical esophagus. The total procedure time was 64.1 ± 37.7 minutes, but the average time from oral incision to pocket creation was 121.2 ± 109.9 seconds.
Conclusions Ultrathin endoscopes may be useful for difficult
esophageal ESD.
Partnering with Students to Develop a Capstone for a Graduate Health Informatics Program
Authors: Jezrawi Rita , Zahorka Derka Stephanie , Warnick Elizabeth , Foley Jasmine , Patel Vritti , Pavithran Neethu , Bernier Thérèse , Wagner Nicole , Barr Neil G. , Maccio Vincent , Leyland Margaret , Lokker Cynthia 
Published: September 2024

Abstract
Objective This study aimed to assess the desirability, feasibility, and sustainability of integrating a project-based capstone course with the course-based curriculum of an interdisciplinary MSc Health Informatics program guided by a student-partnered steering committee and student-centered approach.
Methods We conducted an online cross-sectional survey (n = 87) and three semistructured focus groups (n = 18) of health informatics students and alumni. Survey data were analyzed descriptively. Focus groups were audio-recorded and transcribed verbatim and then analyzed using a general inductive and classic analysis approach.
Results Most students supported including a capstone project but desired an option to work independently or within a group. Students perceived several benefits to capstone courses while concerned over perceived challenges to capstone implementation, evaluation, and managing group processes. The themes identified were (1) professional development, identity, and career advancement, (2) emulating the real world and learning beyond the classroom, (3) embracing new, full-circle learning, (4) anticipated course structure, delivery, and preparation, (5) balancing student choice, interests, and priorities, and (6) concerns over group dynamics, limitations, and support.
Conclusion This study demonstrates the value of having students as partners at each stage in the process from methods conception to course curriculum design. With the steering committee and the curriculum developer, we codeveloped a student-centered course that integrates foundational digital health-related project knowledge acquisition with an inquiry-based project that can be completed independently or in small groups. This study demonstrates the potential benefits and challenges that health informatics educators may consider when (re)designing capstone courses.
Early Recognition of Drug-Induced Febrile Neutropenia Leads to an Improved Outcome in the Trauma Intensive Care Unit: A Case Report
Authors: Khurana Bisman J.K. , Hazarika Amarjyoti , Jain Kajal 
Published: September 2024

AbstractTraumatic brain injury necessitates the use of antiepileptics for seizure prophylaxis, which are associated with multiple side effects including neutropenia, which may be dose dependent or idiosyncratic. We report the case of a young male with traumatic brain injury who developed febrile neutropenia, likely secondary to antiepileptic use. Early recognition and stopping of the drugs with use of granulocyte colony-stimulating factor led to the successful management of the patient.
The Correlation Between CT Findings and Neurosurgical Intervention in Mild Traumatic Brain Injury Patients with Isolated Subdural Hematomas
Authors: Sharma Ashwani , Jain Surendra , Sharma Vinod , Gupta Ashok , Chopra Sanjeev 
Published: September 2024

Abstract
Objective In patients with mild traumatic brain injuries (mTBIs), with Glasgow Coma Scale (GCS) scores of 13 to 15, isolated subdural hematomas (iSDHs) are identified as a prevalent category of intracranial hemorrhage. The primary objective of our research was to investigate the relationship between the characteristics of iSDHs, as revealed through computed tomography (CT) scans on patient admission, and the consequent necessity for neurosurgical intervention.
Materials and Methods This was a 1-year study, employing a prospective observational design at our institution. We enrolled adult trauma patients diagnosed with mTBIs and concurrent iSDHs, intent on documenting the hemorrhages' quantitative parameters such as maximum length and thickness, among other related variables. The eventual execution of neurosurgical procedures constituted our primary outcome, aiming to establish a decisive correlation between CT scan metrics of iSDHs upon admission and the imperative for subsequent surgical intervention.
Results A total of 50 patients were included in our study: 14 patients received a neurosurgical intervention and 36 patients did not. The neurosurgical intervention group had a mean maximum SDH length and thickness that were 38 mm longer and 9.6 mm thicker than those of the non-neurosurgical intervention group (p < 0.001 for both).
Conclusion In this study, we evaluated the odds of a neurosurgical intervention based on hemorrhage characteristics on CT, in patients with an iSDH and mTBI. Once validated in a second population, these data can be used to evaluate the necessity of interhospital transfers and to better inform patients and families of the risk of future neurosurgical intervention and prognosis.
Hematologic Indices and Chronic Subdural Hematoma: A Single-Center Cohort Study
Authors: Barić Hrvoje , Komljenović Sara , Bilić Katarina , Migo William , Vitowanu Julius Mautin , Desnica Andrej , Mrak Goran 
Published: September 2024

Abstract
Objective Chronic subdural hematoma (cSDH) is common, predominantly affects the elderly, often recurs after treatment, and can have serious complications, including death. Inflammation plays an important role in cSDH and it has been previously shown that some laboratory indices are useful as prognostic markers. The aim was to research the role of hematologic and inflammatory markers in cSDH.
Materials and Methods A single-center archival database review to retrieve data on cSDH cases operated on between 2018 and 2020, including: (1) sociodemography (age, gender), (2) clinics (Glasgow Coma Score [GCS], anticoagulants, chronic conditions), (3) laboratory (leukocyte, neutrophil, platelet, C-reactive protein, hemoglobin, red cell distribution width [RDW], neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio [PLR], systemic immune-inflammatory index [SII]), (4) cSDH (size, location, midline shift), and (5) treatment (craniotomy/craniostomy, drainage). Primary outcome was Glasgow Outcome Score (GOS) at discharge and at 1 year, and secondary outcomes were 1 year mortality, resurgery, and recurrence. Hematological and inflammatory indices were compared across two cSDH thickness groups.
Results Seventy-two patients were included, 25 women and 47 men, median age 77 years. Seventeen (23.6%) patients had chronic anticoagulant treatment. The majority had a chronic comorbidity: 19 (26.4%) diabetes, 48 (66.7%) hypertension, and 56 (77.8%) other chronic diseases. Median preoperative GCS was 15. Median cSDH thickness was 22.9 mm, sidedness was equally distributed, and midline shift occurred in 60 (83.3 %) patients, with median midline shift of 8.4 mm. The majority of patients underwent a single craniostomy (n = 44, 61.1%), and in all patients a subdural drainage was placed. Median GOS at discharge and at 1 year postoperatively was 5. Mortality was 11.1%, and 16.7% of patients were lost to follow-up. Within the 1-year follow-up, 27.8% of patients had disease recurrence, 25% underwent a repeat surgery. In the “above” versus “below” 15 mm cSDH thickness group there were significant differences in P count (211.5 vs. 279.5 × 109/L, p = 0.009), RDW (13.3 vs. 12.6, p = 0.031), SII (1782 vs. 2653, p = 0.025), and PLR (26.2 vs. 36.7, p = 0.042).
Conclusion Hematological indices bear a diagnostic and prognostic potential in cSDH management.
Understanding the Malignancy Potential of Cutaneous/Subcutaneous Lesions: Insight from 9,202 Day-Surgery Procedures
Authors: Başak Fatih , Kudaş İlyas , Acar Aylin , Tosun Hüsna , Calışkan Yahya Kemal 
Published: September 2024

Abstract
Objectives: Cutaneous and subcutaneous lesions often go unnoticed or disregarded, yet they can harbor malignant potential. These seemingly innocuous bumps and lumps vary in size and nature, necessitating thorough evaluation by health care professionals. In this study encompassing 9,202 day-surgery procedures, we sought to elucidate the malignancy risk associated with cutaneous/subcutaneous lesions.
Materials and Methods: Conducted as a descriptive case-control investigation, our study enrolled patients undergoing excision for such lesions from 2009 to 2018. Patients were stratified into study (malignancy confirmed by histopathology) and control groups. Comprehensive data collection included demographic profiles, pathology reports, surgical details, and follow-up outcomes.
Results: Analysis of 9,202 excision procedures involving 8,962 patients revealed epidermal/tricholemmal cyst as the most prevalent lesion type (34.5%), followed by lipomas (21.8%). Malignancies were identified in 1.1% of cases, predominantly affecting older individuals (mean age: 60.3 ± 16.2 years). While malignancy incidence correlated with advancing age, no significant gender disparity was observed (p < 0.001 and p = 0.353, respectively).
Conclusion: Our findings underscore the imperative of vigilance toward cutaneous and subcutaneous lesions, as they may harbor malignancy. Timely assessment by health care providers is paramount to promptly identify and manage potentially malignant lesions. With malignancy detected in over 1% of cases, our study emphasizes the necessity for meticulous evaluation and appropriate intervention strategies to mitigate associated risks effectively.
Diversity and transition of periodic motion of a periodically excited soft-impacting machinery
Authors: Shi Yuqing , Yang Jiuhe 
Published: September 2024

Abstract
Dynamics of a periodically excited vibro-impact system with soft impacts is investigated. Essential features of period-one multi-impact motion group and correlated transition characteristics in low-frequency range are discussed in detail by the way of two-parameter bifurcation space providing qualitative domains for different periodic motions. The main focus is given to the effect of sensitive parameters including constraint stiffness k
0, clearance threshold b, and damping parameter ζ on the system response. The low-frequency characteristics in the finite-dimensional parameter space are particularly explored. It is found that the increase of k
0 induces multi-type bifurcation of period-one double-impact symmetrical motion, which induces a rich variety of periodic motions, and period-one multi-impact motion group orbit primarily exist in the small-clearance b and low-frequency ω zone. Based on the evolution irreversibility of adjacent period-one multi-impact orbit, the mechanism of singularies appearing in pairs and two different transition zones (hysteresis and liguliform zones) is studied, the result of which provides a theoretical reference value for the common low-frequency vibration instability phenomenon in the field of mechanical engineering. For small-damping coefficient ζ, period-one multi-impact motion has a large quantity, and the main bridge for the transition of adjacent period-one multi-impact motion is liguliform zone, which embraces period-one multi-impact asymmetrical motion and period-n multi-impact subharmonic motion and a certain chaotic zone. For large-damping coefficient ζ, the amount of period-one multi-impact motion group is reduced, and the main bridge for the transition of adjacent period-one multi-impact motion is hysteresis zone, where adjacent period-one multi-impact orbits can coexist according to initial conditions. As designing and renovating impact mechanical equipment, the reasonable matching law of dynamic parameters can be determined through two-parameter bifurcation space, which is conducive to making the system work in stable periodic motion and obtaining larger instantaneous impact velocity.
A nanosecond level current pulse capture taper optical fiber probe based on micron level nitrogen-vacancy color center diamond
Authors: Bian 卞 Yuchen 雨辰 , Mao 毛 Yangfan 扬帆 , Chen 陈 Honghao 鸿浩 , Ge 葛 Shiyu 仕宇 , Lu 卢 Wentao 文韬 , Wang 王 Chengkun 成坤 , An 安 Sihan 思瀚 , Du 杜 Guanxiang 关祥 
Published: September 2024

Abstract
This work demonstrates a micron-sized nanosecond current pulse probe using a quantum diamond magnetometer. A micron-sized diamond crystal affixed to a fiber tip is integrated on the end of a conical waveguide. We demonstrate real-time visualization of a single 100 nanosecond pulse and discrimination of two pulse trains of different frequencies with a coplanar waveguide and a home-made PCB circuit. This technique finds promising applications in the display of electronic stream and can be used as a pulse discriminator to simultaneously receive and demodulate multiple pulse frequencies. This method of detecting pulse current is expected to provide further detailed analysis of the internal working state of the chip.
PDMS/CNT electrodes with bioamplifier for practical in-the-ear and conventional biosignal recordings
Authors: Sanguantrakul Jongsook , Hemakom Apit , Soonrach Tharapong , Israsena Pasin 
Published: September 2024

Abstract

Objective. Potential usage of dry electrodes in emerging applications such as wearable devices, flexible tattoo circuits, and stretchable displays requires that, to become practical solutions, issues such as easy fabrication, strong durability, and low-cost materials must be addressed. The objective of this study was to propose soft and dry electrodes developed from polydimethylsiloxane (PDMS) and carbon nanotube (CNT) composites. Approach. The electrodes were connected with both conventional and in-house NTAmp biosignal instruments for comparative studies. The performances of the proposed dry electrodes were evaluated through electromyogram, electrocardiogram, and electroencephalogram measurements. Main results. Results demonstrated that the capability of the PDMS/CNT electrodes to receive biosignals was on par with that of commercial electrodes (adhesive and gold-cup electrodes). Depending on the type of stimuli, a signal-to-noise ratio of 5–10 dB range was achieved. Significance. The results of the study show that the performance of the proposed dry electrode is comparable to that of commercial electrodes, offering possibilities for diverse applications. These applications may include the physical examination of vital medical signs, the control of intelligent devices and robots, and the transmission of signals through flexible materials.
A low-swelling alginate hydrogel with antibacterial hemostatic and radical scavenging properties for open wound healing
Authors: Ma Xuebin , Fu Xiao , Meng Jianwen , Li Hongmei , Wang Fang , Shao Huarong , Liu Yang , Liu Fei , Zhang Daizhou , Chi Bo , Miao Jinlai 
Published: September 2024

Abstract
Development of a low-cost and biocompatible hydrogel dressing with antimicrobial, antioxidant, and low swelling properties is important for accelerating wound healing. Here, a multifunctional alginate hydrogel dressing was fabricated using the D-(+)-gluconic acid δ-lactone/CaCO3 system. The addition of hyaluronic acid and tannic acid (TA) provides the alginate hydrogel with anti-reactive oxygen species (ROS), hemostatic, and pro-wound healing properties. Notably, soaking the alginate hydrogel in a poly-ϵ-lysine (EPL) aqueous solution enables the alginate hydrogel to be di-crosslinked with EPL through electrostatic interactions, forming a dense network resembling ‘armor’ on the surface. This simple one-step soaking strategy provides the alginate hydrogel with antibacterial and anti-swelling properties. Swelling tests demonstrated that the cross-sectional area of the fully swollen multifunctional alginate hydrogel was only 1.3 times its initial size, thus preventing excessive wound expansion caused by excessive swelling. After 5 h of in vitro release, only 7% of TA was cumulatively released, indicating a distinctly slow-release behavior. Furthermore, as evidenced by the removal of 2,2-diphenyl-1-picrylhydrazyl free radicals, this integrated alginate hydrogel systems demonstrate a notable capacity to eliminate ROS. Full-thickness skin wound repair experiment and histological analysis of the healing site in mice demonstrate that the developed multifunctional alginate hydrogels have a prominent effect on extracellular matrix formation and promotion of wound closure. Overall, this study introduces a cost-effective and convenient multifunctional hydrogel dressing with high potential for clinical application in treating open wounds.
Mechanisms regulating trophic transfer in the Humboldt Upwelling System differ across time scales
Authors: Xue Tianfei , Frenger Ivy , Hauschildt Jaard , Oschlies Andreas 
Published: September 2024

Abstract
The Humboldt Upwelling System hosts a highly productive ecosystem with central importance for global fisheries, yet with strong seasonal and interannual variability in the planktonic base of the food chain ultimately affecting fish yield. Understanding the variability in energy transfer within the plankton community in the contemporary climate can provide valuable insights for future projections of planktonic dynamics. Therefore, we use a regional physical-biogeochemical ocean model simulation (CROCO-BioEBUS) from 1990 to 2010 to investigate the underlying mechanisms of seasonal and interannual variability of the trophic transfer. Our model simulations suggest that, on an interannual scale, variations in trophic transfer are governed by variations in the offshore surface flow that modulate the plankton cross-shore distribution. Weak offshore surface flow, as simulated during the El Niño period, allows the zooplankton to stay relatively close to the shore, leading to more efficient grazing and trophic transfer compared to years with strong offshore flow. This mechanism differs from the seasonal one, where the mixed layer depth is the primary driver of variations in plankton dynamics, including trophic transfer. Our results highlight that mechanisms controlling plankton trophic transfer differ across time scales, and thus stress that extrapolating solely from seasonal findings to understand long-term trophic transfer changes in the context of climate change may be insufficient.
The health and wellbeing co-benefits of policies and programs to address climate change in urban areas: a scoping review
Authors: Becvarik Z A , White L V , Lal A 
Published: September 2024

Abstract
Existing research suggests that a health-centred response to the climate crisis would support immediate and more ambitious action that minimises adverse health outcomes of climate change whilst providing additional co-benefits for population health. This review aimed to identify and assess literature that examines the health and wellbeing co-benefits of climate action in urban areas and to identify potential co-benefits that could be incorporated into policy or programme evaluation. We searched Scopus, PubMed and Web of Science, and screened titles, abstracts, and full-text. Peer-reviewed studies in English were included if they focused on health and wellbeing co-benefits of climate change adaptation and/or mitigation policies and programmes specific to urban areas. Our analysis found that all 39 studies in this review identified positive health and wellbeing co-benefits, with the majority focusing on transport policies and cross-sectoral mitigation and adaptation. All included studies employed a diverse array of modelling methodology, with multiple models and interdisciplinary approaches to evaluate co-benefits. Co-benefits ranged from reduced or avoided mortality and morbidity to social and economic health benefits. The degree of co-benefits differed according to the policies themselves; the policy sector; and vulnerability, demographic and/or geographic factors. Nine studies identified negative trade-offs of climate action. The review’s findings add to existing literature in support of the value and importance of assessing the health and wellbeing co-benefits of climate action. The review also highlights the need for further identification and quantification of a comprehensive set of health and wellbeing co-benefits, improved data reporting and granularity, as well as research evaluating the impact of climate action that considers how vulnerability, demographic, geographic or other factors interact with policy implementation. This research is critical in informing the cost-effective prioritisation and coordination of climate policies that maximise human health benefits and promote health equity by minimising trade-offs for vulnerable groups.
CSR And Health Care Management: Conceptual Approach Towards a Sustainable and Socially Responsible Organisation
Authors: Banerjee Ipsita 
Published: September 2024

Abstract
“Good Health and Well-being” is one of the prime Sustainable Development goals which was declared by UNDP as a crucial factor to improve the world. There is no doubt regarding the fact that health is an asset to human beings. Considering the recent covid-19 pandemic scenario it has been observed that in case of economically emerging nations, such as India, it is exceedingly difficult for the governments to singlehandedly look after the health care facilities. Now, it is already known that since 2013 (CSR), that is, Corporate Social Responsibility is a mandate for corporates having a Net worth of more than Rs. 500 crores. In this regard the present research has tried to explore the ways in which CSR activities can be used to enhance health communication for providing better health care facilities in India. The results derived from of this research have further highlighted the contribution of CSR done by pharmaceutical industry in SDG 3. The research methodology has been based on post-positivism philosophy where both qualitative and quantitative secondary data will be collected from CSR reports and relevant case studies. Thereafter, based on the Theoretical Framework of Triple Bottomline theory (People, Planet and Profit), the research has suggested relevant CSR policies which can contribute towards “Good Health and Well-being”.