bluuebunny/crossref_metadata_2025_split huggingface dataset:
The puzzle of public opposition to TTIP in Germany
Authors: Chan Alexsia T. , Crawford Beverly K. 
Published: November 2017

AbstractGermany is pivotal to the success of any trade agreement between the European Union and the United States. As the third largest exporter in the world, Germany is dependent on open markets; throughout the post-war period, government support for free trade has been unequivocal. Despite these positive incentives for expanding free trade, both German business and the wider public voiced fierce opposition to the Transatlantic Trade and Investment Partnership (TTIP). TTIP became a flash point for the German public to overcome collective action problems and create a broad protest movement against a free trade agreement for the first time in German history. This movement enabled the public to successfully exercise influence on German foreign economic policy-making, which had long been protected from public pressure. By 2015, the success of that pressure in penetrating the policy-making apparatus combined with growing government concern about the potential of international firms to undermine national policy. As a result of the confluence of these two forces, German leaders changed their position in TTIP negotiations.
A Randomized Trial of Two Cover Gowns Comparing Contamination of Healthcare Personnel During Removal of Personal Protective Equipment
Authors: Mana Thriveen S. C. , Tomas Myreen E. , Cadnum Jennifer L. , Jencson Annette L. , Piedrahita Christina T. , Donskey Curtis J. 
Published: November 2017

In a randomized trial, a gown designed to allow easy removal at the neck and with increased skin coverage and snugness of fit at the wrist significantly reduced contamination of personnel during personal protective equipment (PPE) removal. Our results suggest that simple modifications of PPE can reduce contamination of personnel.Infect Control Hosp Epidemiol 2018;39:97–100
A comparison of mental health legislation in five developed countries: a narrative review
Authors: Cronin T. , Gouda P. , McDonald C. , Hallahan B. 
Published: November 2017

ObjectivesTo describe similarities and differences in mental health legislation between five jurisdictions: the Republic of Ireland, England and Wales, Scotland, Ontario (Canada), and Victoria (Australia).MethodsAn in-depth examination was undertaken focussing on the process of involuntary admission, review of Admission Orders and the legal processes in relation to treatment in the absence of patient consent in each of the five jurisdictions of interest.ResultsAll jurisdictions permit the detention of a patient if they have a mental disorder although the definition of mental disorder varies between jurisdictions. Several additional differences exist between the five jurisdictions, including the duration of admission prior to independent review of involuntary detention and the role of supported decision making.ConclusionsAcross the five jurisdictions examined, largely similar procedures for admission, detention and treatment of involuntary patients are employed, reflecting adherence with international standards and incorporation of human rights-based principles. Differences exist in relation to the criteria to define mental disorder, the occurrence of automatic review hearings in a timely fashion after a patient is involuntarily admitted and the role for supported decision making under mental health legislation.
Effect of neuroactive nutritional supplementation on body weight and composition in growing puppies
Authors: Wang Wei , Brooks Melissa , Gardner Cari , Milgram Norton 
Published: November 2017

AbstractNutritional factors can dramatically affect development of young animals during the early stage of life. The objective of the present study was to examine the effects of a neuroactive nutritional supplement (NNS) containing DHA, taurine, carotenoids and vitamins on the body weight and body composition of growing puppies. A total of twenty-four 2-month-old Beagles were fed a nutritionally complete and balanced base diet and a control supplement daily during an initial 1-month baseline assessment, after which they were divided into control and treatment groups. They were fed daily either control or treatment supplements in addition to the base diet from 3 to 12 months of age. Lean body mass and fat mass were assessed using quantitative magnetic resonance scans at 0 (baseline), 3, 6 and 9 months of treatment. Total body weight and lean body mass did not differ between groups over time. The puppies in the treatment group showed a trend of reduced fat gain compared with those in the control group, and with a marginally significant difference at 6 months (P= 0·05). At 3 months, insulin-like growth factor 1 was higher (P= 0·02) in the treatment group compared with the control group. At 9 months, fasting lipid levels were lower (P< 0·05) and fat-oxidation metabolite 3-hydroxybutyrate was higher (P< 0·05) in the treatment group compared with the control group. These results may indicate that NNS has an impact on puppy growth and development, possibly by promoting fat metabolism; further investigation would be necessary to determine the full impact of this supplement on growth and development.
Long-chainn-3 PUFA in vegetarian women: a metabolic perspective
Authors: Burdge Graham C. , Tan Sze-Yen , Henry Christiani Jeyakumar 
Published: November 2017

AbstractVegetarian diets have been associated with health benefits, but paradoxically are low in EPA and DHA which are important for development, particularly of the central nervous system, and for health. Humans have limited capacity for synthesis of EPA and DHA from α-linolenic acid, although this is greater in women than men. Oily fish and, to a lesser extent, dairy foods and meat are the primary sources of EPA and DHA in the diet. Exclusion of these foods from the diet by vegetarians is associated consistently with lower EPA and DHA status in vegetarian women compared with omnivores. The purpose of the present review was to assess the impact of low EPA and DHA status in vegetarian pregnancies on the development and health of children. EPA and DHA status was lower in breast milk and in infants of vegetarian mothers than those born to omnivore mothers, which suggests that in the absence of pre-formed dietary EPA and DHA, synthesis from α-linolenic acid is an important process in determining maternal EPA and DHA status in pregnancy. However, there have been no studies that have investigated the effect of low maternal DHA status in vegetarians on cognitive function in children. It is important to address this gap in knowledge in order to be confident that vegetarian and vegan diets during pregnancy are safe in the context of child development.
Terroir in the New World: Hedonic Estimation of Vineyard Sale Prices in California
Authors: Cross Robin , Plantinga Andrew J. , Stavins Robert N. 
Published: November 2017

AbstractIn the Old-World vineyards of Europe, a key concept that plays an important role in the production and appreciation of wines isterroir, which refers to the special characteristics of a place that impart unique qualities to the wine produced. We examine whetherterroirmatters in the New-World wines produced in California's Napa and Sonoma Counties by conducting a hedonic price analysis of vineyard sales over the period 1991 to 2007 to determine the relative effects on vineyard sales prices of designated appellations versus biophysical site attributes commonly associated withterroir, such as slope, aspect, elevation, and climate. Because vineyards that are sold are not necessarily representative of the universe of vineyards, we employ Heckman's two-stage econometric approach to control for possible sample-selection bias. We find that intrinsic site attributes and designated appellations influence vineyard prices, although our results are stronger and more consistent with regard to the influence of appellations. This finding indicates thatterroirmatters economically, even if the designated appellations have relatively less connection in reality withterroir. (JEL Classifications: C2, Q11)
Exploring the Influence of Regional Brand Equity in an Emerging Wine Sector
Authors: Canziani Bonnie , Byrd Erick T. 
Published: November 2017

AbstractWe measure the effects of consumer-perceived regional brand equity on future intentions toward regional wine purchases and winery visits for U.S.-based North Carolina (NC) wines. Visitor data were collected at 23 regional wineries, including demographics, motives, and perceptions of and intentions toward NC wines. SPSS™ and SmartPLS™ were employed in analyzing the model presented. Knowledge and regional wine brand equity influence wine consumer motives, which in turn affect intentions. Product-centered motives were more important than experience motives for visiting regional wineries. (JEL Classifications: L66, L83, M31)
Managerial Styles in Privately Owned Domestic Organizations in Russia: Heterogeneity, Antecedents, and Organizational Implications
Authors: Balabanova Evgeniya , Rebrov Alexey , Koveshnikov Alexei 
Published: November 2017

ABSTRACTDrawing on a dataset consisting of 344 personal interviews, participant observations, and internal documents collected in 26 privately owned business organizations in Russia, the study aims at complementing existing research on Russian indigenous management in three ways. First, it examines the managerial styles of key individuals (i.e. owners and/or CEOs) in the case organizations. Hence, it taps into the existing heterogeneity of managerial styles, the so-calledgroupvergence, found in contemporary Russian organizations, and documents their idiosyncratic features, such as the transformational nature of authoritarian leadership. Second, the study explores the antecedents of the identified styles to establish what factors contribute to their emergence and thus sheds light on how the heterogeneous managerial styles in Russian organizations come into existence. Finally, the study investigates how the identified styles manifest themselves in organizations by influencing organizational goals and strategies, organizational structures, supporting mechanisms, relationships between organizational members, and reward systems. It therefore elaborates on the organizational implications of the styles and highlights the mechanisms of their sustainable diffusion to lower organizational levels in Russian organizations.
Explaining variations in the diversity of parasitoid assemblages in a biosphere reserve of Mexico: evidence from vegetation, land management and seasonality
Authors: González-Moreno A. , Bordera S. , Leirana-Alcocer J. , Delfín-González H. , Ballina-Gómez H.S. 
Published: November 2017

AbstractInsect fauna biodiversity in natural protected areas has not been thoroughly studied. Therefore, the aim of this work was to assess whether and how vegetation types, land management and seasonality influence the diversity of Ichneumonidae (Hymenoptera) in the Ría Lagartos Biosphere Reserve (Mexico). A sampling programme was conducted using Malaise traps from 2008 to 2009 in three vegetation types, each with two conservation zones (core and buffer zones). Three seasons were considered: rainy, dry and north-winds (isolated storms from November to February). A total of 336 species were identified. Rarefaction and Generalized Linear Model indicated higher species richness and abundance, respectively, in the buffer zone of the dry forest; possible explanations for this finding include the intermediate disturbance hypothesis, wherein diversity can be higher in sites where disturbance is not very frequent or very intense, and the ‘enemies hypothesis’, wherein structural complexity and high plant diversity favour increased predators or, in this case, parasitoids. Diversity was higher during the rainy season, which may have been due to the higher availability of resources. Vegetation and management had a positive impact on the Coc (attack cocoons and pupae) and Myc (attack concealed larvae living in the fruiting bodies of mushrooms) parasitoid guilds. Members of the Coc guild are generalist parasitoids, which may be favoured in complex vegetation with a high richness of potential hosts and non-hosts. The Myc guild requires certain environmental conditions that promote fungal growth, such as humidity, that is absent in the other vegetation types of savannah and coastal dune scrubland.
WOMEN’S EMPOWERMENT AND GENDER INEQUALITY IN ADOLESCENT NUTRITIONAL STATUS: EVIDENCE FROM THE INDONESIAN FAMILY LIFE SURVEY
Authors: Kunto Yohanes Sondang , Bras Hilde 
Published: November 2017

SummaryIn contrast to the extensive knowledge on the association between women’s empowerment and the nutritional status of children under the age of five, relatively little is known about the influence of women’s empowerment on adolescents’ nutritional status. This study aimed to assess the association between women’s empowerment and gender inequalities in adolescent nutritional status. Data were from the Indonesian Family Life Survey (IFLS) covering the period 1997 to 2015, and consisted of 16,683 observations from 13,396 adolescents between the ages of 10 and 19 years born in 6781 families. Three indicators of women’s empowerment were used: mother’s education, mother’s bargaining power and mother’s working status. Multivariate linear regression with robust standard errors was used to examine whether and how these indicators of women’s empowerment influenced adolescent nutritional status. Interaction terms were added to analyse how the association between women’s empowerment and adolescent nutritional status differed by gender. The results showed that mother’s education and mother’s working status were significantly associated with adolescent nutritional status, particularly with height-for-age. Adolescents of well-educated mothers had a higher height-for-age while those who were raised by mothers with a blue-collar job had a lower height-for-age. Although no gender differences were found for height-for-age, gender differences for BMI-for-age were obvious, with boys having a lower BMI-for-age than girls. Interactions between indicators of mother’s empowerment and gender showed that the gender gap in BMI-for-age was smaller for adolescents of more educated mothers. However, further analyses of food consumption patterns showed that boys whose mothers were more educated consumed more fast food and had higher instant noodle consumption than girls, thus suggesting gender bias in new disguise.
A review on metronidazole: an old warhorse in antimicrobial chemotherapy
Authors: Leitsch David 
Published: November 2017

AbstractThe 5-nitroimidazole drug metronidazole has remained the drug of choice in the treatment of anaerobic infections, parasitic as well as bacterial, ever since its development in 1959. In contrast to most other antimicrobials, it has a pleiotropic mode of action and reacts with a large number of molecules. Importantly, metronidazole, which is strictly speaking a prodrug, needs to be reduced at its nitro group in order to become toxic. Reduction of metronidazole, however, only takes place under very low concentrations of oxygen, explaining why metronidazole is exclusively toxic to microaerophilic and anaerobic microorganisms. In general, resistance rates amongst the pathogens treated with metronidazole have remained low until the present day. Nevertheless, metronidazole resistance does occur, and for the treatment of some pathogens, especiallyHelicobacter pylori, metronidazole has become almost useless in some parts of the world. This review will give an account on the current status of research on metronidazole's mode of action, metronidazole resistance in eukaryotes and prokaryotes, and on other 5-nitroimidazoles in use.
In vitro and in vivo efficacy of diamidines against Trypanosoma equiperdum strains
Authors: Gillingwater Kirsten 
Published: November 2017

AbstractTrypanosoma equiperdum is a protozoan parasite responsible for causing Dourine, a debilitating neglected veterinary disease, found worldwide affecting equids. It is the only pathogenic trypanosome species that does not require an invertebrate vector for transmission, thus being passed from animal to animal via coitus. At present, there is no officially recognized form of chemotherapeutic treatment and therefore all confirmed (or suspected) cases of infected animals must be slaughtered immediately. For many global communities and farming populations, which rely heavily on their animals for their livelihood, such stringent regulations can seriously enhance the socio-economic problems attributing to poverty. Two reference drugs, together with 37 novel diamidine compounds were tested in vitro using a 72 h drug sensitivity assay to determine their efficacy against two axenically adapted T. equiperdum strains. Further in vivo investigations in mouse models of infection against 4 ‘true’ T. equiperdum strains were performed using the 17 most active diamidines. Single bolus doses of 10 mg kg−1, given i.p. were administered to NMRI mice infected with one of the 4 T. equiperdum strains. The results obtained from this study show that experimentally T. equiperdum can indeed be effectively treated with chemotherapy using in vivo mouse models of infection.
Development of early morphological awareness in Greek: Epilinguistic versus metalinguistic and inflectional versus derivational awareness
Authors: DIAMANTI VASSILIKI , BENAKI ARGYRO , MOUZAKI ANGELIKI , RALLI ASIMINA , ANTONIOU FAYE , PAPAIOANNOU SOPHIA , PROTOPAPAS ATHANASSIOS 
Published: November 2017

ABSTRACTThis cross-sectional study examined the development of morphological awareness in Greek children 4–7 years old. A distinction was adopted between epilinguistic control, evidenced in judgment tasks and indicative of elementary levels of awareness, and metalinguistic awareness, evidenced in production tasks and indicative of full-blown conscious awareness. The morphological domains of inflectional and derivational morphology were specifically contrasted to determine whether they follow distinct developmental trajectories. Trial-level performance data from 236 children in four morphological awareness tasks as a function of age were modeled using generalized additive models. Significant performance increase with age was found for all four awareness tasks. The results further indicated that production of derivational morphemes was consistently more difficult than production of inflectional morphemes and judgment of derivational morphemes, whereas the differences between the two inflectional and between the two judgment tasks were not significant. This suggests that at these ages, epilinguistic control is similarly effective for the two morphological domains whereas full metalinguistic awareness of derivational morphology trails behind that of inflectional morphology, at least as measured by these specific tasks. The findings highlight the need for early tracking and finer distinctions within the domain of morphological awareness, to identify and potentially enhance the critical skills related to the development of vocabulary and reading comprehension.
Systematic review of infant and young child complementary feeding practices in South Asian families: the India perspective
Authors: Manikam Logan , Prasad Ankita , Dharmaratnam Abina , Moen Christy , Robinson Alexandra , Light Alexander , Ahmed Sonia , Lingam Raghu , Lakhanpaul Monica 
Published: November 2017

AbstractObjectiveSuboptimal nutrition among children remains a problem among South Asian (SA) families. Appropriate complementary feeding (CF) practices can greatly reduce this risk. Thus, we undertook a systematic review of studies assessing CF (timing, dietary diversity, meal frequency and influencing factors) in children aged <2 years in India.DesignSearches between January 2000 and June 2016 in MEDLINE, EMBASE, Global Health, Web of Science, OVID Maternity & Infant Care, CINAHL, Cochrane Library, BanglaJOL, POPLINE and WHO Global Health Library. Eligibility criteria: primary research on CF practices in SA children aged 0–2 years and/or their families. Search terms: ‘children’, ‘feeding’ and ‘Asians’ and derivatives. Two researchers undertook study selection, data extraction and quality appraisal (EPPI-Centre Weight of Evidence).ResultsFrom 45 712 abstracts screened, sixty-four cross-sectional, seven cohort, one qualitative and one case–control studies were included. Despite adopting the WHO Infant and Young Child Feeding guidelines, suboptimal CF practices were found in all studies. In twenty-nine of fifty-nine studies, CF was introduced between 6 and 9 months, with eight studies finding minimum dietary diversity was achieved in 6–33 %, and ten of seventeen studies noting minimum meal frequency in only 25–50 % of the study populations. Influencing factors included cultural influences, poor knowledge on appropriate CF practices and parental educational status.ConclusionsThis is the first systematic review to evaluate CF practices in SA in India. Campaigns to change health and nutrition behaviour and revision of nationwide child health nutrition programmes are needed to meet the substantial unmet needs of these children.
Improved outcome for AML patients over the years 2000–2014
Authors: Bertoli Sarah , Tavitian Suzanne , Huynh Anne , Borel Cécile , Guenounou Sarah , Luquet Isabelle , Delabesse Eric , Sarry Audrey , Laurent Guy , Attal Michel , Huguet Françoise , Bérard Emilie , Récher Christian 
Published: November 2017

AbstractFew recent studies from registries have reported an improvement in overall survival of younger patients with acute myeloid leukemia (AML). However, reasons for this improvement are not defined. We analyzed the therapeutic course and outcome of 976 patients treated by intensive chemotherapy between 2000 and 2014. The number of patients receiving allogeneic stem cell transplantation in first or second response significantly increased over time whereas autologous transplantation was progressively abandoned. In the 513 younger patients, there were no differences in first complete response, induction failure, incidence of relapse, or non-relapse mortality over time. The period of time was significantly associated with a better overall survival especially in 2010–2014. The 2010–2014 period effect was still significant in multivariate analysis and was independent of allogeneic stem cell transplantation. In the 463 older patients, there was a significant interaction between the period and leukocytosis in multivariate analysis meaning that the 2010–2014 period had only an impact in patients with white blood cell count >50 giga/L for response and overall survival. Progresses have been made in each phase of the therapeutic course of younger AML patients resulting in survival improvement. In older patients, the outcome of hyperleukocytic patients has significantly improved in 2010–2014.