bluuebunny/crossref_metadata_2025_split huggingface dataset:
First report of Stegomyia aegypti (= Aedes aegypti) in Mexico City, Mexico
Authors: KURI‐MORALES P. , CORREA‐MORALES F. , GONZÁLEZ‐ACOSTA C. , SÁNCHEZ‐TEJEDA G. , DÁVALOS‐BECERRIL E. , FERNANDA JUÁREZ‐FRANCO M. , DÍAZ‐QUIÑONEZ A. , HUERTA‐JIMENÉZ H. , MEJÍA‐GUEVARA M. D. , MORENO‐GARCÍA M. , GONZÁLEZ‐ROLDÁN J. F. 
Published: January 2017

AbstractStegomyia aegypti (= Aedes aegypti) (Diptera: Culicidae) is a species of mosquito that is currently widespread in Mexico. Historically, the mosquito has been distributed across most tropical and subtropical areas lower than 1700 m a.s.l. Currently, populations that are found at higher altitudes in regions with cold and dry climates suggest that these conditions do not limit the colonization and population growth of S. aegypti. During a survey of mosquitoes in September 2015, larvae of S. aegypti mosquitoes were found in two different localities in Mexico City, which is located at about 2250 m a.s.l. Mexico City is the most populous city in Mexico and has inefficient drainage and water supply systems. These factors may result in the provision of numerous larval breeding sites. Mosquito monitoring and surveillance are now priorities for the city.
Hemin binding by Porphyromonas gingivalis strains is dependent on the presence of A‐LPS
Authors: Rangarajan M. , Aduse‐Opoku J. , Paramonov N.A. , Hashim A. , Curtis M.A. 
Published: January 2017

Porphyromonas gingivalis is a Gram‐negative black pigmenting anaerobe that is unable to synthesize heme [Fe(II)‐protoporphyrin IX] or hemin [Fe(III)‐protoporphyrin IX‐Cl], which are important growth/virulence factors, and must therefore derive them from the host. Porphyromonas gingivalis expresses several proteinaceous hemin‐binding sites, which are important in the binding/transport of heme/hemin from the host. It also synthesizes several virulence factors, namely cysteine‐proteases Arg‐ and Lys‐gingipains and two lipopolysaccharides (LPS), O‐LPS and A‐LPS. The gingipains are required for the production of the black pigment, μ‐oxo‐bisheme {[Fe(III)PPIX]2 O}, which is derived from hemoglobin and deposited on the bacterial cell‐surface leading to the characteristic black colonies when grown on blood agar. In this study we investigated the role of LPS in the deposition of μ‐oxo‐bisheme on the cell‐surface. A P. gingivalis mutant defective in the biosynthesis of Arg‐gingipains, namely rgpA/rgpB, produces brown colonies on blood agar and mutants defective in Lys‐gingipain (kgp) and LPS biosynthesis namely porR, waaL, wzy, and pg0129 (α‐1, 3‐mannosyltransferase) produce non‐pigmented colonies. However, only those mutants lacking A‐LPS showed reduced hemin‐binding when cells in suspension were incubated with hemin. Using native, de‐O‐phosphorylated and de‐lipidated LPS from P. gingivalis W50 and porR strains, we demonstrated that hemin‐binding to O‐polysaccharide (PS) and to the lipid A moiety of LPS was reduced compared with hemin‐binding to A‐PS. We conclude that A‐LPS in the outer‐membrane of P. gingivalis serves as a scaffold/anchor for the retention of μ‐oxo‐bisheme on the cell surface and pigmentation is dependent on the presence of A‐LPS.
Do post‐concussion‐like symptom responses change following exercise or sports participation in a non‐concussed cohort?
Authors: Balasundaram A. P. , Athens J. , Schneiders A. G. , McCrory P. , Sullivan S. J. 
Published: January 2017

The purposes of this study were (a) to determine the reliable change in post‐concussion‐like symptoms reported following self‐selected exercise or sports activities and (b) to explore the potential influence of gender and exercise parameters on post‐concussion‐like symptoms reported by a non‐concussed cohort following exercise/training. A pre‐to‐post observational design was used. A convenience sample of students aged 18–30 years who visited a university recreation center to engage in their chosen exercise activity and a purposeful sample of men's and women's rugby union players engaged in their regular training sessions were included in the study. All participants reported their symptoms using the symptom scale of the Sport Concussion Assessment Tool 2. The reliable change index was used to determine the change in symptom scores reported from pre‐to post‐exercise/training. Multiple linear regression analysis was used to model the exercise variables to explain the impact on the reporting of symptoms. A total of 260 participants (146 males and 114 females) completed their self‐selected exercise activity or rugby union training. Approximately two‐thirds of all participants did not demonstrate a change (increase or decrease) in total symptom score (201/260, 77.9%) and/or symptom severity score (212/260, 81.9%) from pre‐to post‐exercise/training. The symptom response following exercise or sports training did not change in the majority of participants. Clinicians need to be aware of these findings to make informed decisions on return‐to‐play following a concussive brain injury.
TheSUFBC2D complex is required for the biogenesis of all major classes of plastid Fe‐S proteins
Authors: Hu Xueyun , Kato Yukako , Sumida Akihiro , Tanaka Ayumi , Tanaka Ryouichi 
Published: January 2017

SummaryIron‐sulfur (Fe‐S) proteins play crucial roles in plastids, participating in photosynthesis and other metabolic pathways. Fe‐S clusters are thought to be assembled on a scaffold complex composed ofSUFB,SUFCandSUFDproteins. However, several additional proteins provide putative scaffold functions in plastids, and, therefore, the contribution ofSUFB, C and D proteins to overall Fe‐S assembly still remains unclear. In order to gain insights regarding Fe‐S cluster biosynthesis in plastids, we analyzed the complex composed ofSUFB, C and D in Arabidopsis by blue native‐polyacrylamide gel electrophoresis. Using this approach, a major complex of 170kDa containing all subunits was detected, indicating that these proteins constitute aSUFBC2D complex similar to their well characterized bacterial counterparts. The functional effects ofSUFB,SUFCorSUFDdepletion were analyzed using an inducibleRNAi silencing system to specifically target the aforementioned components; resulting in a decrease of various plastidic Fe‐S proteins including the PsaA/B and PsaC subunits of photosystem I, ferredoxin and glutamine oxoglutarate aminotransferase. In contrast, the knockout of potential Fe‐S scaffold proteins,NFU2 andHCF101, resulted in a specific decrease in the PsaA/B and PsaC levels. These results indicate that the functions ofSUFB,SUFCandSUFDfor Fe‐S cluster biosynthesis cannot be replaced by other scaffold proteins and thatSUFBC2D,NFU2 andHCF101 are involved in the same pathway for the biogenesis ofPSI. Taken together, our results providein vivoevidence supporting the hypothesis thatSUFBC2D is the major, and possibly sole scaffold in plastids.
MYB12 and MYB22 play essential roles in proanthocyanidin and flavonol synthesis in red‐fleshed apple (Malus sieversii f. niedzwetzkyana)
Authors: Wang Nan , Xu Haifeng , Jiang Shenghui , Zhang Zongying , Lu Ninglin , Qiu Huarong , Qu Changzhi , Wang Yicheng , Wu Shujing , Chen Xuesen 
Published: January 2017

SummaryFlavonoids are major polyphenol compounds in plant secondary metabolism. Wild red‐fleshed apples (Malus sieversii f. niedzwetzkyana) are an excellent resource because of their much high flavonoid content than cultivated apples. In this work, R6R6, R6R1 and R1R1 genotypes were identified in an F1 segregating population of M. sieversii f. niedzwetzkyana. Significant differences in flavonoid composition and content were detected among the three genotypes by ultra‐performance liquid chromatography/quadrupole time‐of‐flight mass spectrometry analysis. Furthermore, two putative flavonoid‐related genes encoding R2R3‐MYB transcription factors, designated MYB12 and MYB22, were cloned and characterized. The expression patterns of MYB12 and MYB22 directly correlated with those of leucoanthocyanidin reductase and flavonol synthase, respectively. Their roles in flavonoid biosynthesis were identified by overexpression in apple callus and ectopic expression in Arabidopsis. MYB12 expression in the Arabidopsis TT2 mutant complemented its proanthocyanidin‐deficient phenotype. Likewise, MYB22 expression in an Arabidopsis triple mutant complemented its flavonol‐deficient phenotype. MYB12 could interact with bHLH3 and bHLH33 and played an essential role in proanthocyanidin synthesis. MYB22 was found to activate flavonol pathways by combining directly with the flavonol synthase promoter. Our findings provide a valuable perspective on flavonoid synthesis and provide a basis for breeding elite functional apples with a high flavonoid content.
On solutions of variable-order fractional differential equations
Authors: Akgül Ali , Inc Mustafa , Baleanu Dumitru 
Published: January 2017

Numerical calculation of the fractional integrals and derivatives is the code tosearch fractional calculus and solve fractional differential equations. The exactsolutions to fractional differential equations are compelling to get in real applications, due to the nonlocality and complexity of the fractional differential operators, especially for variable-order fractional differential equations. Therefore, it is significant to enhanced numerical methods for fractional differential equations. In this work, we consider variable-order fractional differential equations by reproducing kernel method. There has been much attention in the use of reproducing kernels for the solutions to many problems in the recent years. We give two examples to demonstrate how efficiently our theory can be implemented in practice.
Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring

bla
NDM-1
Authors: Yao Yancheng , Falgenhauer Linda , Kempf Volkhard A. J. , Hogardt Michael , Göttig Stephan , Imirzalioglu Can , Chakraborty Trinad 
Published: January 2017

ABSTRACT

The draft genome sequences of two clonal, pandrug-resistant
Serratia marcescens
clinical isolates were determined. The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids indicating a large pool of transmissible antibiotic resistance genes.
Draft Genome Sequence of Hypervirulent and Vaccine Candidate Streptococcus suis Strain SC19
Authors: Teng Lin , Dong Xingxing , Zhou Yang , Li Zhiwei , Deng Limei , Chen Huanchun , Wang Xiaohong , Li Jinquan 
Published: January 2017

ABSTRACT

Streptococcus suis
, a zoonotic bacterium found primarily in pigs, has been recognized recently as an emerging pathogen of humans. Herein, we describe the genome of
Streptococcus suis
strain SC19, a hypervirulent and vaccine candidate strain isolated from a pig amid the 2005 outbreak in China.
Complete Genome Sequence of the Triclosan- and Multidrug-Resistant Pseudomonas aeruginosa Strain B10W Isolated from Municipal Wastewater
Authors: Zhong Chuanqing , Nelson Matthew , Cao Guangxiang , Sadowsky Michael J. , Yan Tao 
Published: January 2017

ABSTRACT

Here, we report the complete genome sequence of the triclosan- and multidrug-resistant
Pseudomonas aeruginosa
strain B10W, obtained from municipal wastewater in Hawaii. The bacterium has a 6.7-Mb genome, contains 6,391 coding sequences and 78 RNAs, with an average G+C content of 66.2 mol%.
First Complete Genome Sequence of Genotype III Japanese Encephalitis Virus Isolated from a Stillborn Piglet in India
Authors: Desingu P. A. , Ray Pradeep K. , John Jeny K. , Das T. , Dubal Z. B. , Rajak K. K. , Singh R. K. , Saikumar G. 
Published: January 2017

ABSTRACT
We report here the first complete genome of the Japanese encephalitis virus (JEV) genotype III strain JEV/SW/IVRI/395A/2014, isolated from stillborn piglets in India. It shares 99% identity with strain JaOArS982 and a few other strains from Japan.
Deformational plagiocephaly in normal infants: a systematic review of causes and hypotheses
Authors: De Bock Freia , Braun Volker , Renz-Polster Herbert 
Published: January 2017

BackgroundDeformational plagiocephaly (DP) is one of the most prevalent abnormal findings in infants and a frequent reason for parents to seek paediatric advice.ObjectiveTo systematically review the literature and identify evidence and hypotheses on the aetiology and determinants of DP in otherwise healthy infants.DesignSystematic keyword search in all major biomedical databases to identify peer-reviewed publications reporting (a) empirical research or (b) hypotheses on the aetiology of DP in healthy, term infants. 3150 studies published between 1985 and 2016 and containing relevant keywords were screened. In a two-pronged approach, results were summarised separately for the body of empirical work (22 studies) and the body of hypotheses (110 articles).Review findingsOnly a few empirical studies have examined risk factors in non-selected patient populations on a higher grade methodological level. The most commonly reported risk factors were: male gender, supine sleep position, limited neck rotation or preference in head position, first-born child, lower level of activity and lack of tummy time. Agreement between empirical studies was poor for most exposures, including supine sleep position, tummy time and use of car seats. The articles reporting hypotheses on the aetiology of DP cover a wide field of environmental and biological factors, but include little suggestions as to the potential influence of the everyday care environment of the baby.Conclusions and relevanceThe evidence on the aetiology of DP is fragmentary and heterogeneous. In addition, factors possibly relevant to the development of DP have not been appreciated in the scientific discussion.
Improving care standards for patients with spinal trauma combining a modified e-Delphi process and stakeholder interviews: a study protocol
Authors: Sharwood Lisa N , Stanford Ralph , Middleton James W , Burns Brian , Joseph Anthony , Flower Oliver , Rigby Oran , Ball Jonathon , Dhaliwal Shelly 
Published: January 2017

IntroductionAround 300 people sustain a new traumatic spinal cord injury (TSCI) in Australia each year; a relatively low incidence injury with extremely high long-term associated costs. Care standards are inconsistent nationally, lacking in consensus across important components of care such as prehospital spinal immobilisation, timing of surgery and timeliness of transfer to specialist services. This study aims to develop ‘expertly defined’ and agreed standards of care across the majority of disciplines involved for these patients.Methods and analysisA modified e-Delphi process will be used to gain consensus for best practice across specific clinical early care areas for the patient with TSCI; invited participants will include clinicians across Australia with relevant and significant expertise. A rapid literature review will identify available evidence, including any current guidelines from 2005 to 2015. Level and strength of evidence identified, including areas of contention, will be used to formulate the first round survey questions and statements. Participants will undertake 2–3 online survey rounds, responding anonymously to questionnaires regarding care practices and indicating their agreement or otherwise with practice standard statements. Relevant key stakeholders, including patients, will also be interviewed face to face.Ethics and disseminationEthics approval for this study was obtained by the NSW Population & Health Services Research Ethics Committee on 14 January 2016 (HREC/12/CIPHS/74). Seeking comprehensive understanding of how the variation in early care pathways and treatment can be addressed to achieve optimal patient outcomes and economic costs; the overall aim is the agreement to a consistent approach to the triage, treatment, transport and definitive care of acute TSCI victims. The agreed practice standards of care will inform the development of a Clinical Pathway with practice change strategies for implementation. These standards will offer a benchmark for state-wide and potentially national policy.
Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts
Authors: Simrén Magnus , Törnblom Hans , Palsson Olafur S , van Tilburg Miranda A L , Van Oudenhove Lukas , Tack Jan , Whitehead William E 
Published: January 2017

ObjectiveOur aim was to evaluate the association between visceral hypersensitivity and GI symptom severity in large cohorts of patients with functional GI disorder (FGID) and to adjust for psychological factors and general tendency to report symptoms.DesignWe included five cohorts of patients with FGIDs (IBS or functional dyspepsia; n=1144), who had undergone visceral sensitivity testing using balloon distensions (gastric fundus, descending colon or rectum) and completed questionnaires to assess GI symptom severity, non-GI somatic symptoms, anxiety and depression. Subjects were divided into sensitivity tertiles based on pain/discomfort thresholds. GI symptom severity was compared between sensitivity tertiles in each cohort and corrected for somatisation, and anxiety and depression.ResultsIn all five cohorts, GI symptom severity increased gradually with increasing visceral sensitivity, with significant differences in GI symptom severity between the sensitivity tertiles (p<0.0001), with small to medium effect sizes (partial η2: 0.047–0.11). The differences between sensitivity tertiles remained significant in all cohorts after correction for anxiety and depression, and also after correction for non-GI somatic symptom reporting in all of the cohorts (p<0.05).ConclusionsA gradual increase in GI symptom severity with increasing GI sensitivity was demonstrated in IBS and functional dyspepsia, which was consistent across several large patient groups from different countries, different methods to assess sensitivity and assessments in different parts of the GI tract. This association was independent of tendency to report symptoms or anxiety/depression comorbidity. These findings confirm that visceral hypersensitivity is a contributor to GI symptom generation in FGIDs.
Transcatheter aortic valve implantation: new hope in the management of valvular heart disease
Authors: Metaxa Sofia , Ioannou Adam , Missouris Constantinos G 
Published: January 2017

ABSTRACTSevere calcific aortic stenosis is relatively common, and unless treated with valve replacement it carries an adverse prognosis. A large number of patients, however, are denied surgery due to their advanced age or coexistent medical conditions that increase perioperative cardiovascular risks. Transcatheter aortic valve implantation (TAVI), a technique in which a bioprosthetic valve is inserted via a catheter and implanted within the diseased native aortic valve, is a new therapeutic modality for treatment of older patients with severe symptomatic aortic stenosis and other comorbidities, who have an inherently high surgical risk. This review will provide an overview of the pivotal trials in the development of TAVI; while also investigating important complications and limitations of the procedure and evaluating how new valves are being designed and clinically evaluated, with the ultimate goal of reducing potential complications and expanding the use of TAVI to lower-risk patient cohorts.
FIRST:

F

ace

I

dentity

R

ecognition in

S

mar

T

Bank
Authors: Li Qianmu , Li Tao , Xia Bin , Ni Ming , Liu Xiaoqian , Zhou Qifeng , Qi Yong 
Published: January 2017

The rapid development of information era has influenced to realize the notion of Smart Bank via approaches like paperless services and interactive self-service systems. Since the traditional methods of identity verification are insecure and cumbersome for supporting these services, Smart Bank has been questioned. To overcome the limitations of current identity verification, it is imperative to explore an effective recognition strategy considering the trade-off between security and customer experience, which can conveniently collect identity information and accurately distinguish people. However, few research and existing systems have been reported for an integrated solution of identity verification satisfying convenient and secure banking environment. In this paper, we propose, implement, and deploy an integrated system named FIRST (Face Identity Recognition in SmarT Bank), which is a customized platform for the identity verification via face recognition in Smart Bank. FIRST uses Gabor surface feature and Fisherfaces, which can provide accurate face recognition within acceptable training time. For information acquisition, our system employs the patch-based face quality assessment, which efficiently extracts valuable faces (i.e. front face) from video streams. Furthermore, FIRST provides a distributed environment to effectively manage recognition tasks and massive data. Since March 2015, FIRST has been successfully deployed on 1800 self-service terminals in Jiangsu Province by ABC (Agriculture Bank of China), and is under deployment by State Grid in China.
Detailed Echocardiographic Phenotyping in Breast Cancer Patients
Authors: Narayan Hari K. , Finkelman Brian , French Benjamin , Plappert Theodore , Hyman David , Smith Amanda M. , Margulies Kenneth B. , Ky Bonnie 
Published: January 2017

Background:
Cardiovascular disease in patients with breast cancer is of growing concern. The longitudinal effects of commonly used therapies, including doxorubicin and trastuzumab, on cardiac remodeling and function remain unknown in this population. We aimed to define the changes in echocardiographic parameters of structure, function, and ventricular-arterial coupling, and their associations with left ventricular ejection fraction (LVEF) and heart failure symptoms.

Methods:
In a longitudinal prospective cohort study of 277 breast cancer participants receiving doxorubicin (Dox), trastuzumab (Tras), or both (Dox+Tras), we obtained 1249 echocardiograms over a median follow-up of 2.0 (interquartile range, 1.0–3.0) years. Left ventricular structure, diastolic and contractile function, and ventricular-arterial coupling measures were quantified in a core laboratory blinded to participant characteristics. We evaluated changes in echocardiographic parameters over time, and used repeated-measures regression models to define their association with LVEF decline and recovery. Linear regression models defined the association between early changes in these parameters and subsequent changes in LVEF and heart failure symptoms.

Results:

Overall, 177 (64%) received Dox, 51 (18%) received Tras, and 49 (18%) received Dox+Tras. With Dox, there was a sustained, modest decrease in LVEF over the follow-up duration (1-year change in LVEF –3.6%; 95% confidence interval [CI], –4.4% to –2.8%; 3-year change –3.8%; 95% CI, –5.1% to –2.5%). With Tras, a similar LVEF decline was observed at 1 year (–4.5%; 95% CI, –6.0% to –2.9%) and 3 years (–2.8%; 95%CI, –5.3 to –0.4%). Participants receiving Dox+Tras demonstrated the greatest declines at 1 year (–6.6%; 95% CI, –8.2 to –5.0%), with partial recovery at 3 years (–2.8%; 95% CI, –4.8 to –0.8%). LVEF declines and recovery were associated primarily with changes in systolic volumes, longitudinal and circumferential strain, and ventricular-arterial coupling indices, effective arterial elastance (Ea) and the coupling ratio Ea/Ees
sb
, without evidence for effect modification across therapies. Early changes in volumes, strain, and Ea/Ees
sb
at 4 to 6 months were associated with 1- and 2-year LVEF changes. Similarly, early changes in strain and Ea were associated with worsening heart failure symptoms at 1 year.

Conclusions:
Doxorubicin and trastuzumab resulted in modest, persistent declines in LVEF at 3 years. Changes in volumes, strain, and ventricular-arterial coupling were consistently associated with concurrent and subsequent LVEF declines and recovery across therapies.