bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of prenatal corticosteroid use in spontaneous preterm labor in the Brazilian Multicenter Study on Preterm Birth (EMIP)
Authors: Dias Tabata Z. , Passini Renato , Tedesco Ricardo P. , Lajos Giuliane J. , Rehder Patricia M. , Nomura Marcelo L. , Costa Maria L. , Oliveira Paulo F. , Sousa Maria H. , Cecatti Jose G. ,   the Brazilian Multicenter Study on Preterm Birth (EMIP) study group
Published: August 2017

AbstractObjectiveTo evaluate prenatal corticosteroid use in women experiencing spontaneous preterm labor and preterm delivery.MethodsThe present cross‐sectional multicenter study analyzed interview data from patients attending 20 hospitals in Brazil owing to preterm delivery between April 1, 2011 and July 30, 2012. Patients were stratified based on preterm delivery occurring before 34 weeks or at 34–36+6 weeks of pregnancy, and the frequency of prenatal corticosteroid use at admission was compared. Prenatal corticosteroid use, sociodemographic data, obstetric characteristics, and neonatal outcomes were examined.ResultsThere were 1455 preterm deliveries included in the present study; 527 (36.2%) occurred before 34 weeks of pregnancy and prenatal corticosteroids were used in 285 (54.1%) of these pregnancies. Among neonates delivered at 32–33+6 weeks, prenatal corticosteroid use was associated with lower pneumonia (P=0.026) and mortality (P=0.029) rates. Among neonates delivered at 34–36+6 weeks, prenatal corticosteroid use was associated with longer neonatal hospital admission (P<0.001), and an increased incidence of 5‐minute Apgar scores below 7 (P=0.010), endotracheal intubation (P=0.042), surfactant use (P=0.006), neonatal morbidities (P=0.048), respiratory distress (P=0.048), and intraventricular hemorrhage (P=0.023).ConclusionPreterm labor and late preterm delivery were associated with worse neonatal outcomes following prenatal corticosteroids. This could reflect a sub‐optimal interval between administration and delivery.
A systematic review of primary outcomes and outcome measure reporting in randomized trials evaluating treatments for pre‐eclampsia
Authors: Duffy James M.N. , Hirsch Martin , Gale Chris , Pealing Louise , Kawsar Anusuya , Showell Marian , Williamson Paula R. , Khan Khalid S. , Ziebland Sue , McManus Richard J. ,   the International Collaboration to Harmonize Outcomes for Pre‐eclampsia (iHOPE)
Published: August 2017

AbstractBackgroundAn evaluation of outcome reporting is required to develop a core outcome set.ObjectivesTo assess primary outcomes and outcome measure reporting in pre‐eclampsia trials.Search strategyFive online databases were searched from inception to January 2016 using terms including “preeclampsia” and “randomized controlled trial”.Selection criteriaRandomized controlled trials evaluating treatments for pre‐eclampsia published in any language were included.Data collection and analysisPrimary outcomes and data on outcome measure reporting were systematically extracted and categorized.Main resultsOverall, 79 randomized trials including data from 31 615 women were included. Of those, 38 (48%) reported 35 different primary outcomes; 28 were maternal outcomes and seven were fetal/neonatal outcomes. Three randomized trials reported composite outcomes, incorporating between six and nine outcome components. The method of definition or measurement was infrequently or poorly reported. Even when outcomes were consistent across trials, different methods of definition or measurement were frequently described.ConclusionsIn randomized trials evaluating interventions for pre‐eclampsia, critical information related to the primary outcome, including definition and measurement, is regularly omitted. Developing a core outcome set for pre‐eclampsia trials would help to inform primary outcome selection and outcome measure reporting.
Effect of the organic loading rate on the performance and microbial populations during the anaerobic treatment of tequila vinasses in a pilot‐scale packed bed reactor
Authors: Arreola‐Vargas Jorge , Snell‐Castro Raúl , Rojo‐Liera Nuvia M , González‐Álvarez Víctor , Méndez‐Acosta Hugo O 
Published: August 2017

AbstractBACKGROUNDPilot‐scale studies focused on evaluating the robustness of biofilm‐based anaerobic digestion processes for further application at full‐scale are scarce. Therefore, the aim of this work was to evaluate the performance of a 445 L packed bed reactor (PBR) operated at different organic loading rates (OLRs between 4 and 12.5 g COD L‐1 d‐1) for the treatment of tequila vinasses. The reactor performance was correlated with the microbial dynamics to elucidate the specific role of the microbial communities in the degradation pathways that govern the process.RESULTSThe PBR was operated for 231 days under different OLRs showing a stable performance. The COD removal and methane yield were maintained throughout the reactor operation at 86–89% and 0.24–0.28 L CH4 g‐1 CODadded, respectively. Meanwhile, the highest volumetric methane production rate of 3.03 L CH4 d‐1 L‐1 was reached at the highest OLR, 12.5 g COD L‐1 d‐1. Regarding microbial dynamics, the Bacteria and Archaea populations were able to adapt to the OLR disturbances, favoring the interactions between syntrophic Bacteria and Methanosaeta at high OLRs.CONCLUSIONThis work contributes to the scarce information regarding anaerobic treatment of tequila vinasses at pilot‐scale and demonstrates that the PBR is a promising and robust configuration that allows treating higher OLRs than currently reported technologies. © 2017 Society of Chemical Industry
Bioelectrochemical enhancement of organic matter mineralization and sulfate reduction during acidogenesis
Authors: Li Yue , Zhao Zhiqiang , Yang Yafei , Zhao Huimin , Zhang Yaobin 
Published: August 2017

AbstractBACKGROUNDThe microbial electrolysis cell (MEC) has been widely reported as an efficient strategy to enhance anaerobic digestion. However, the role of the MEC during acidogenesis for treatment of sulfate‐containing wastes remains unclear. In this study a pair of electrodes was placed into an acidogenic reactor to form MEC‐based acidogenesis to investigate its performance in sulfate‐containing wastewater treatment.RESULTSThe MEC obviously improved anaerobic acidogenesis treating sulfate‐containing wastewater. Higher COD removal and sulfate reduction were obtained in the MEC‐based acidogenesis even under high sulfate loading conditions. The MEC accelerated the conversion of substrate to acetate, indicating that acidogenesis was enhanced. Fluorescence in situ hybridization (FISH) analysis showed that exoelectrogenic bacteria were enriched in the anodic biofilm.CONCLUSIONThe syntrophic metabolism between anodic exoelectrogenic bacteria and anaerobic fermentative bacteria might accelerate the anodic decomposition of complex substrates as well as cathodic sulfate reduction, then providing a positive environment for sulfate reduction during acidogenesis. © 2017 Society of Chemical Industry
Early intervention with non‐ablative fractional laser to improve cutaneous scarring—A randomized controlled trial on the impact of intervention time and fluence levels
Authors: Karmisholt Katrine E. , Wenande Emily , Thaysen‐Petersen Daniel , Philipsen Peter A. , Paasch Uwe , Haedersdal Merete 
Published: August 2017

Background and ObjectivesLaser treatment in the early phases of wound healing may reduce scar formation. However, little is known on when in the early wound healing phases laser exposure most optimally should be provided and at which fluence levels. This study investigates the clinical effect of non‐ablative‐fractional‐laser (NAFL) performed at three early time points at a range of fluence levels versus untreated control scars.Materials and MethodsA randomized, controlled, intra‐individual trial with erbium‐glass 1,540 nm NAFL versus no laser treatment on sixteen subjects receiving 10 standardized full‐thickness punch‐biopsy wounds. A single NAFL‐exposure was applied to test‐wounds 1 day before, immediately after, or 2 weeks after wounding. Three fluence levels provided deep and superficial energy depositions (range 30–70 mJ/microbeam). Primary outcome comprised the total‐score of the observer part of Patient‐Observer‐Scar‐Assessment‐Scale (POSAS), performed by blinded on‐site assessment at 3 months follow‐up. Secondary outcomes were clinical evaluation on visual‐analogue‐scale (VAS), reflectance measurements, and histology.ResultsNAFL‐treatment applied 1 day before, immediately after or 2 weeks after wounding had the potential to offer subtle but detectable improvement in clinical scar appearance compared to untreated controls. Thus, NAFL‐exposure 1 day before wounding (POSAS‐total: median of 15 vs. control‐median of 16, P = 0.03, VAS: median 4.1 vs. control‐median 5.5, P = 0.03, medium‐fluence), as well as immediately‐, and 2 weeks after wounding (POSAS‐total: P ≤ 0.05, low‐fluence) induced improvement compared to untreated controls. No significant differences in dyschromia were detected between NAFL‐treated and control scars. Histology showed subtle changes towards more mature interwoven bundles of collagen in NAFL‐treated scars as compared to controls.ConclusionsThis study indicates that a single NAFL‐treatment at low to medium fluence performed 1 day prior, or in the early phases of wound healing, may have the potential to optimize scar formation in full thickness wounds. Lasers Surg. Med. 50:28–36, 2018. © 2017 Wiley Periodicals, Inc.
Oil–Water Separation Using Superhydrophobic PET Membranes Fabricated Via Simple Dip‐Coating Of PDMS–SiO2 Nanoparticles
Authors: Han Sang Wook , Kim Kwang‐Dae , Seo Hyun Ook , Kim Il Hee , Jeon Chan Seok , An Jung Eun , Kim Ju Hwan , Uhm Sunghyun , Kim Young Dok 
Published: August 2017

AbstractThe surfaces of commercially available polyester (PET) and polypropylene (PP) are superhydrophobically modified via the deposition of polydimethylsiloxane (PDMS)‐coated SiO2 nanoparticles (P‐SiO2) and PDMS binder. The adhesion of P‐SiO2 is stronger on PET than on PP due to a stronger chemical interaction between PET and PDMS, which is attributed to the higher surface energy of PET than PP. The waterproof ability and oil separation rate of the P‐SiO2‐coated PET (dip‐PET) membranes are studied as a function of membrane thickness, and the influence of oil viscosity on the oil separation efficiency is investigated. Optimal membrane thickness should be selected in a given environment for the facile oil–water separation and the dip‐PET membrane is chemically stable and can be used repetitively for oil–water separation. Finally, an automated prototype instrument is introduced for the dip‐coating process. It is suggested that our dip‐PET is a promising solution for oil–water separation in real‐world oil‐spill applications.
Dual temperature sensors with different emissivities in radiosondes for the compensation of solar irradiation effects with varying air pressure
Authors: Lee Sang‐Wook , Park Eun Uk , Choi Byung Il , Kim Jong Chul , Woo Sang‐Bong , Park Seongchong , Yang Seung Gu , Kim Yong‐Gyoo 
Published: August 2017

ABSTRACTOne of the challenges in temperature measurements in the upper air using a radiosonde is the correction of solar radiation effects. A prerequisite for the correction is in situ measurements of solar radiation. In this study, a new technique for the measurement of solar irradiation followed by the temperature correction was developed using dual temperature sensors with different emissivities. The principle is that the radiation intensity is calculated by using the temperature difference between two thermistors coated with different materials (one with graphite and the other with aluminium) and then the irradiance obtained is used for the correction. As a first stage, the effect of air pressure on the temperature correction process using dual thermistors was examined. The temperature difference between the two sensors was found to be linearly proportional only to the irradiance up to 360 W m−2, regardless of air pressure from 10 to 1000 hPa at room temperature. This provides a way to calculate the irradiance by simply measuring the temperature difference between the two sensors. The calculated irradiance showed a difference of less than 45 W m−2 (13% of the maximum irradiance) compared to the irradiance measured with a calibrated pyranometer. The extended uncertainty of the calculated irradiance was 53.5 W m−2 (coverage factor k = 2). A reference temperature sensor in the shade was used to obtain a correction formula as a function of air pressure and calculated irradiance. When the temperature was corrected using the calculated irradiance, the extended uncertainty of the corrected temperature was 0.98 K (k = 2).
Impact Response Comparison Between Parametric Human Models and Postmortem Human Subjects with a Wide Range of Obesity Levels
Authors: Zhang Kai , Cao Libo , Wang Yulong , Hwang Eunjoo , Reed Matthew P. , Forman Jason , Hu Jingwen 
Published: August 2017

ObjectiveField data analyses have shown that obesity significantly increases the occupant injury risks in motor vehicle crashes, but the injury assessment tools for people with obesity are largely lacking. The objectives of this study were to use a mesh morphing method to rapidly generate parametric finite element models with a wide range of obesity levels and to evaluate their biofidelity against impact tests using postmortem human subjects (PMHS).MethodsFrontal crash tests using three PMHS seated in a vehicle rear seat compartment with body mass index (BMI) from 24 to 40 kg/m2 were selected. To develop the human models matching the PMHS geometry, statistical models of external body shape, rib cage, pelvis, and femur were applied to predict the target geometry using age, sex, stature, and BMI. A mesh morphing method based on radial basis functions was used to rapidly morph a baseline human model into the target geometry. The model‐predicted body excursions and injury measures were compared to the PMHS tests.ResultsComparisons of occupant kinematics and injury measures between the tests and simulations showed reasonable correlations across the wide range of BMI levels.ConclusionsThe parametric human models have the capability to account for the obesity effects on the occupant impact responses and injury risks.
Molstack—Interactive visualization tool for presentation, interpretation, and validation of macromolecules and electron density maps
Authors: Porebski Przemyslaw J. , Sroka Piotr , Zheng Heping , Cooper David R. , Minor Wladek 
Published: August 2017

AbstractOur understanding of the world of biomolecular structures is based upon the interpretation of macromolecular models, of which ∼90% are an interpretation of electron density maps. This structural information guides scientific progress and exploration in many biomedical disciplines. The Protein Data Bank's web portals have made these structures available for mass scientific consumption and greatly broaden the scope of information presented in scientific publications. The portals provide numerous quality metrics; however, the portion of the structure that is most vital for interpretation of the function may have the most difficult to interpret electron density and this ambiguity is not reflected by any single metric. The possible consequences of basing research on suboptimal models make it imperative to inspect the agreement of a model with its experimental evidence. Molstack, a web‐based interactive publishing platform for structural data, allows users to present density maps and structural models by displaying a collection of maps and models, including different interpretation of one's own data, re‐refinements, and corrections of existing structures. Molstack organizes the sharing and dissemination of these structural models along with their experimental evidence as an interactive session. Molstack was designed with three groups of users in mind; researchers can present the evidence of their interpretation, reviewers and readers can independently judge the experimental evidence of the authors' conclusions, and other researchers can present or even publish their new hypotheses in the context of prior results. The server is available at http://molstack.bioreproducibility.org.
A direct visual servoing‐based framework for the 2016 IROS Autonomous Drone Racing Challenge
Authors: Jung Sunggoo , Cho Sungwook , Lee Dasol , Lee Hanseob , Shim David Hyunchul 
Published: August 2017

AbstractThis paper presents a framework for navigating in obstacle‐dense environments as posed in the 2016 International Conference on Intelligent Robots and Systems (IROS) Autonomous Drone Racing Challenge. Our framework is based on direct visual servoing and leg‐by‐leg planning to navigate in a complex environment filled with many similar frame‐shaped obstacles to fly through. Our indoor navigation method relies on the velocity measurement by an optical flow sensor since the position measurements from GPS or external cameras are not available. For precision navigation through a sequence of obstacles, a center point–matching method is used with the depth information from the onboard stereo camera. The guidance points is directly generated in three‐dimensional space using the two‐dimensional image data to avoid accumulating the error from the sensor drift. The proposed framework is implemented on a quadrotor‐based aerial vehicle, which carries an onboard vision‐processing computer for self‐contained operation. Using the proposed method, our drone was able to finished in first place in the world‐premier IROS Autonomous Drone Racing Challenge.
Insights into the Adsorption of Resveratrol on Graphene Oxide: A First‐Principles Study
Authors: Zhao Meilian , Lai Qiao , Guo Jinlin , Guo Yong 
Published: August 2017

AbstractTrans‐resveratrol (TRA) has been extensively used in medicine and health products because of its strong biological activity. The solid‐phase extraction sorbent for separation of TRA by graphene oxide (GO) is designed. In this study, the interactions between TRA and GO are analysed by first‐principles calculations with M06‐2X functional at the 6‐311++G(d,p) level. The adsorption of TRA on GO is stronger than that on graphene, which is attributed to epoxide, hydroxyl and carboxyl functional groups in GO. Interaction analysis shows that hydrogen bonds and π‐π interactions exist between TRA and GO surface. The adsorption of TRA depends on the type of oxygen‐containing group in GO. Epoxide group in GO is much more attractive for TRA than hydroxyl and carboxyl group. In addition, solvent effects have also been studied, the result shows that the adsorption weakens with the increase of dielectric constant of solvent. The result is significant in the development of solid‐phase extraction sorbent for TRA.
Facile Synthesis of Nitrovanillin‐ Appended Porphyrin and Its Utilization as Potent, Recyclable, Naked‐Eye CN− and F− Ion Sensor
Authors: Dar Tawseef Ahmad , Sankar Muniappan 
Published: August 2017

AbstractNitrovanillin porphyrin (1) was synthesized in good yield and successfully utilized as colorimetric, naked‐eye sensor for toxic CN− and F− ions. The synthesized probe detects CN− and F− ions via anion induced deprotonation, which brings about drastic spectral and colorimetric changes, among the commonly known anions such as OAc−, H2PO4−, Cl−, Br−, I−, ClO4−, HSO4− and PF6−. The toxic CN− and F− ions interact selectively with the –OH protons of 1 as established via 1H NMR, UV‐Visible and fluorescence spectroscopic methods. The sensor could detect F− ions ∼1.1 ppm and CN− ions ∼ 1.34 ppm which is very appreciable and promising.
Erectile Function Predicts Sexual Satisfaction in Men With Spinal Cord Injury
Authors: Gomes Cristiano M. , Miranda Eduardo P. , de Bessa José , Bellucci Carlos Henrique Suzuki , Battistella Linamara Rizzo , Abdo Carmita Helena Najjar , Bruschini Homero , Srougi Miguel , Mulhall John P. 
Published: August 2017

Abstract

Introduction
Spinal cord injury (SCI) is usually a sudden traumatic event and has a negative effect on sexual function.

Aim
To evaluate the characteristics of sexual activity in men with SCI and identify predictors of being sexually active and having a satisfactory sex life.

Methods
We assessed sexual activity profiles of men with SCI from a Brazilian tertiary rehabilitation center from February to August 2012. All patients older than 18 years with SCI for longer than 1 year were invited to participate. We analyzed age, time since SCI, patient age at SCI, employment status, partner status, completeness of lesion, functional independence, urinary continence, and Sexual Health Inventory for Men (SHIM) score.

Main Outcome Measures
The SHIM was used to assess erectile function (EF). Satisfaction with sex life was analyzed as a dichotomous variable. Predictors of an active and satisfactory sex life were identified using univariable and multivariable analyses.

Results
We evaluated 295 men with mean age of 40.7 ± 14.5 years. Most patients had a complete SCI (65.1%) and 159 (53.9%) were incontinent. The median SHIM score was 5 (interquartile range = 0–16) and only 71 men (24.1%) had a SHIM score of at least 17. Of these men, 159 (53.9%) were sexually active. Only 63 men (39.6%) were satisfied with their sex life after SCI. In univariable analysis, all variables were associated with an active sex life. Those with a SHIM score of at least 17 had a greater likelihood of being sexually active (odds ratio = 116, 95% confidence interval = 14–432). EF was the only parameter associated with a satisfactory sex life (odds ratio = 1.3, 95% confidence interval = 1.2–1.4).

Conclusions
Most men with SCI were sexually inactive and/or dissatisfied with their sex life. Age, duration of SCI, completeness of SCI, continence, having a partner, and good EF were identified as predictors of an active sex life. However, only EF was a predictor of a satisfactory sex life.
Gomes CM, Miranda EP, de Bessa J, et al. Erectile Function Predicts Sexual Satisfaction in Men With Spinal Cord Injury. Sex Med 2017;5:e148–e155.
Recovery of Surgical Equipment Sterile Processing During a Floodwater Boil Advisory
Authors: Shelton Stephen , Hamm Jay , Olatosi Bankole , Johnson R. Ory 
Published: August 2017

AbstractExcessive rainfall and dam failures resulted in floodwater contaminating our public water supply. The endotoxin risk in the contaminated water created challenges in recovery of sterile processing for our surgical equipment. Recovery plans should include a potable water source and a method to connect it to the required location. We share our solution of plumbing our sterile processing equipment to tanker-transported potable water sources. (Disaster Med Public Health Preparedness. 2018; 12: 415–418)
A national register-based study of paediatric varicella hospitalizations in Denmark 2010–2016
Authors: HELMUTH I. G. , POULSEN A. , MØLBAK K. 
Published: August 2017

SUMMARYVaricella, usually a mild disease of childhood, can also cause complications and hospitalization. Universal varicella immunization is implemented in several countries worldwide, but not in Denmark. Taking advantage of unique national registers, we aimed to estimate the incidence of paediatric varicella hospitalizations and assess determinants for hospitalization. For this purpose, we designed a nationwide, retrospective register study of paediatric varicella hospitalizations and applied a case–cohort design and logistic regression analysis comparing hospitalized varicella patients to a sample of the entire paediatric population in Denmark. Varicella patients were identified in The Danish National Patient Register and referents were randomly selected from the Danish Civil Registration System. The incidence of paediatric varicella admissions was 11/100 000 children 0–18 years of age/year. Of admitted children 67·1% had complications and 30·0% had underlying disease. All categories of underlying disease significantly increased the odds of hospitalization as well as male gender and not having been born in Denmark. In conclusion, we found a considerable burden of paediatric varicella disease in Danish hospitals, of similar magnitude as in other European countries comparable to Denmark. With this study we have provided epidemiological data needed for considering implementation of varicella vaccine in Denmark.