bluuebunny/crossref_metadata_2025_split huggingface dataset:
Soutien et cohésion sociale dans les crèches et les ontmoetingsplaatsen , en Belgique
Authors: Vandenbroeck Michel , Geens Naomi 
Published: June 2017

Sachant que la question de la cohésion sociale se pose de plus en plus dans nos villes et qu’un ensemble de recherches s’accordent aujourd’hui pour conclure que le soutien social (informel) est probablement l’une des formes de soutien à la parentalité les plus universelles, cet article analyse le potentiel des crèches pour contribuer à deux objectifs distincts mais liés : le soutien social, comme un soutien aux parents, et la cohésion sociale, comme objectif sociétal. Les données empiriques comprennent des observations effectuées dans deux crèches à Gand et à Bruxelles, des entretiens collectifs réalisés avec des parents usagers de ces crèches, des entretiens collectifs avec les personnels de ces crèches et des entretiens collectifs avec des parents qui fréquentent avec leurs enfants un lieu de rencontre parents et enfants (ontmoetingsplaats) à Bruxelles. Les résultats conduisent à penser que les expériences de lieux de rencontre parents-enfants pourraient inspirer les équipes des crèches.
Investigating Interrater Reliability in an Online RN-to-BSN Program: Disparate Conclusions
Authors: Kilanowski Jill F. , Abbott Miriam Bowers 
Published: June 2017

Background:
Interrater reliability of student-written assignments within a nursing education program is a desirable characteristic to ensure uniform quality of academic work. As online programs that advance RNs to baccalaureate-prepared nurses (i.e., RN-to-BSN programs) grow in popularity, the challenges of quality control increase.

Method:
Grading data representing mean, median, mode, and range from 19 course sections in an online RN-to-BSN program were submitted. Data were analyzed for measures of central tendency with a query of interrater reliability.

Results:
The data indicate that instructors assess student performance at a uniformly high level.

Conclusion:

The data lead to two disparate conclusions: student performance is high and is reliably assessed as such, or the online program suffers from grade inflation. Such disparate conclusions are uniquely endemic to any program that serves the RN-to-BSN population, typically high-performing students who have established prior mastery on licensure examinations. [
J Nurs Educ.
2017;56(6):360–363.]
Biomechanical Characterization of Subclinical Keratoconus Without Topographic or Tomographic Abnormalities
Authors: Vinciguerra Riccardo , Ambrósio Renato , Roberts Cynthia J. , Azzolini Claudio , Vinciguerra Paolo 
Published: June 2017

PURPOSE:
To present a case series of patients with subclinical keratoconus with normal topometric (anterior curvature) and tomographic findings in one eye who showed abnormalities detected by Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) in vivo biomechanical assessment.

METHODS:
All patients had a complete ophthalmic examination, including the Corvis ST biomechanical measurements, optical tomography, and pachymetry with Pentacam (Oculus Optikgeräte GmbH), and Placido-based topography with either the Nidek (OPD III Nidek, Gamagori, Japan) or CSO platform (Costruzione Strumenti Oftalmici, Florence, Italy). Inclusion criteria were a clinical diagnosis of ectasia in one eye and normal topometric and tomographic findings in the fellow eye (subclinical keratoconus), including a Belin/Ambrósio Enhanced Ectasia total deviation index from the Pentacam with less than 1.6 standard deviations from normative values and a Corvis Biomechanical Index score of greater than 0.5 in both eyes.

RESULTS:
Tomographic and topographic analysis was normal in one eye and abnormal in the fellow eye in 12 patients. The biomechanical results with the Corvis Biomechanical Index were shown to be abnormal in both eyes of all patients and aided the diagnosis.

CONCLUSIONS:
Biomechanical analysis showed abnormalities, whereas tomography and topography were normal. Basing on these findings, the authors suggest the use of biomechanics as an additional diagnostic tool.

[
J Refract Surg.
2017;33(6):399–407.]
Questionnaires for Measuring Refractive Surgery Outcomes
Authors: Kandel Himal , Khadka Jyoti , Lundström Mats , Goggin Michael , Pesudovs Konrad 
Published: June 2017

PURPOSE:
To identify the questionnaires used to assess refractive surgery outcomes, assess the available questionnaires in regard to their psychometric properties, validity, and reliability, and evaluate the performance of the available questionnaires in measuring refractive surgery outcomes.

METHODS:
An extensive literature search was done on PubMed, MEDLINE, Scopus, CINAHL, Cochrane, and Web of Science databases to identify articles that described or used at least one questionnaire to assess refractive surgery outcomes. The information on content quality, validity, reliability, responsiveness, and psychometric properties was extracted and analyzed based on an extensive set of quality criteria.

RESULTS:
Eighty-one articles describing 27 questionnaires (12 refractive error–specific, including 4 refractive surgery–specific, 7 vision-but-non-refractive, and 8 generic) were included in the review. Most articles (56, 69.1%) described refractive error–specific questionnaires. The Quality of Life Impact of Refractive Correction (QIRC), the Quality of Vision (QoV), and the Near Activity Visual Questionnaire (NAVQ) were originally constructed using Rasch analysis; others were developed using the Classical Test Theory. The National Eye Institute Refractive Quality of Life questionnaire was the most frequently used questionnaire, but it does not provide a valid measurement. The QoV, QIRC, and NAVQ are the three best existing questionnaires to assess visual symptoms, quality of life, and activity limitations, respectively.

CONCLUSIONS:
This review identified three superior quality questionnaires for measuring different aspects of quality of life in refractive surgery. Clinicians and researchers should choose a questionnaire based on the concept being measured with superior psychometric properties.

[
J Refract Surg.
2017;33(6):416–424.]
Small Incision Lenticule Extraction (SMILE) for Hyperopia: Optical Zone Diameter and Spherical Aberration Induction
Authors: Reinstein Dan Z. , Pradhan Kishore R. , Carp Glenn I. , Archer Timothy J. , Gobbe Marine , Sekundo Walter , Khan Raynan , Dhungana Purushottam 
Published: June 2017

PURPOSE:
To evaluate optical zone diameter efficacy and spherical aberration change in hyperopic small incision lenticule extraction (SMILE).

METHODS:
Prospective study of 60 consecutive hyperopic SMILE procedures using the VisuMax femtosecond laser (Carl Zeiss Meditec, Jena, Germany) and matched LASIK procedures with the VisuMax and MEL 80 excimer (Carl Zeiss Meditec) lasers. Inclusion criteria were maximum attempted hyperopic meridian of between +1.00 and +7.00 diopters (D). For SMILE, the transition zone was 2 mm and the mean optical programmed zone was 6.37 mm (range: 6.3 to 6.7 mm). Two LASIK control groups (6.5- and 7-mm optical zone) matched for spherical equivalent treated were generated. Both tangential and axial curvature difference maps were generated for each eye at 3 months. A fixed grid and set of concentric circles were superimposed on the difference map to measure the achieved optical zone diameter.

RESULTS:

Mean attempted spherical equivalent refraction was +5.58 ± 0.95 D (range: +3.20 to +6.50 D) in the SMILE group. By tangential mapping, SMILE programmed at a mean optical zone of 6.37 mm achieved a diameter of 5.03 ± 0.30 mm, similar to 7-mm LASIK (4.96 ± 0.25 mm,
P
= 0.33) but larger than 6.5-mm LASIK (4.53 ± 0.25 mm,
P
< .001). By axial mapping, the achieved optical zone diameter was 6.75 ± 0.31 mm for 6.37-mm SMILE, larger than for both 6.5-mm (6.61 ± 0.21 mm) and 7-mm (6.92 ± 0.14 mm) LASIK (
P
< .01). Spherical aberration changed on average by −0.45 ± 0.22
μ
m for 6.37-mm SMILE, similar to 7-mm LASIK (−0.50 ± 0.21
μ
m,
P
= .29) and less than for 6.5-mm LASIK (−0.69 ± 0.22
μ
m,
P
< .001).

CONCLUSIONS:
The mean achieved optical zone diameter of hyperopic SMILE was found to be larger than the mean achieved optical zone diameter of hyperopic LASIK. Consequently, spherical aberration induction was similar for 6.37-mm SMILE and 7-mm LASIK.

[
J Refract Surg.
2017;33(6):370–376.]
Biomechanical Changes After LASIK Flap Creation Combined With Rapid Cross-Linking Measured With Brillouin Microscopy
Authors: Randleman J. Bradley , Su Johnny P. , Scarcelli Giuliano 
Published: June 2017

PURPOSE:
To evaluate the biomechanical changes occurring after LASIK flap creation and rapid corneal cross-linking (CXL) measured with Brillouin light microscopy.

METHODS:
Porcine eyes (n = 11) were evaluated by Brillouin light microscopy sequentially in the following order: virgin state, after LASIK flap creation, and after rapid CXL. Each eye served as its own control. Depth profile of the Brillouin frequency shift was computed to reveal the depth-dependent changes in corneal stiffness.

RESULTS:

There was a statistically significant reduction of Brillouin shift (reduced corneal stiffness) after LASIK flap creation compared to virgin corneas across total corneal thickness (−0.035 GHz,
P
= .0195) and within the anterior stromal region (−0.104 GHz,
P
= .0039). Changes in the central (−0.029 GHz,
P
= .0391) and posterior (−0.005 GHz,
P
= .99) stromal regions were not significant. There was a small increase in Brillouin shift after rapid cross-linking that was not statistically or clinically significant across total corneal thickness (0.006 GHz,
P
= .4688 for any specific stromal region; 0.002 to 0.009 GHz,
P
> .46 for all).

CONCLUSIONS:
LASIK flap creation significantly reduced Brillouin shift in the anterior third of the stroma in porcine eyes. Rapid corneal cross-linking had no significant effect on Brillouin shift after LASIK flap creation in porcine eyes. With further validation, non-contact, non-perturbative Brillouin microscopy could become a useful monitoring tool to evaluate the biomechanical impact of corneal refractive procedures and corneal cross-linking protocols.

[
J Refract Surg.
2017;33(6):408–414.]
Los manuscritos aljamiado-moriscos de la Bibliothèque nationale d’Algérie
Authors: Roza Candás Pablo 
Published: June 2017

El presente trabajo se ocupa de dos códices aljamiados (n.º 614 y 1944) conservados en la Bibliothèque nationale d’Algérie, cuyo principal interés radica en el hecho de constituir los únicos ejemplares moriscos conservados en el norte de África. Si bien la existencia de estos dos manuscritos nos es conocida desde hace más de un siglo, las referencias por parte de los autores a estos volúmenes han sido más bien escasas y en su mayor parte deficientes. Junto a una completa revisión de las diversas catalogaciones existentes, ofrezco en este trabajo una detallada descripción codicológica que permita un conocimiento más exacto de este fondo morisco norteafricano. De igual manera, me ocupo aquí de la fortuna de estos dos ejemplares desde su composición, posiblemente en tierras de Aragón, hasta su depósito final en esta biblioteca argelina.
T Cell–Derived IL-10 Impairs Host Resistance to Mycobacterium tuberculosis Infection
Authors: Moreira-Teixeira Lúcia , Redford Paul S. , Stavropoulos Evangelos , Ghilardi Nico , Maynard Craig L. , Weaver Casey T. , Freitas do Rosário Ana Paula , Wu Xuemei , Langhorne Jean , O’Garra Anne 
Published: June 2017

Abstract
Tuberculosis (TB), caused by Mycobacterium tuberculosis infection, is a leading cause of mortality and morbidity, causing ∼1.5 million deaths annually. CD4+ T cells and several cytokines, such as the Th1 cytokine IFN-γ, are critical in the control of this infection. Conversely, the immunosuppressive cytokine IL-10 has been shown to dampen Th1 cell responses to M. tuberculosis infection impairing bacterial clearance. However, the critical cellular source of IL-10 during M. tuberculosis infection is still unknown. Using IL-10 reporter mice, we show in this article that during the first 14 d of M. tuberculosis infection, the predominant cells expressing IL-10 in the lung were Ly6C+ monocytes. However, after day 21 postinfection, IL-10–expressing T cells were also highly represented. Notably, mice deficient in T cell–derived IL-10, but not mice deficient in monocyte-derived IL-10, showed a significant reduction in lung bacterial loads during chronic M. tuberculosis infection compared with fully IL-10–competent mice, indicating a major role for T cell–derived IL-10 in TB susceptibility. IL-10–expressing cells were detected among both CD4+ and CD8+ T cells, expressed high levels of CD44 and Tbet, and were able to coproduce IFN-γ and IL-10 upon ex vivo stimulation. Furthermore, during M. tuberculosis infection, Il10 expression in CD4+ T cells was partially regulated by both IL-27 and type I IFN signaling. Together, our data reveal that, despite the multiple immune sources of IL-10 during M. tuberculosis infection, activated effector T cells are the major source accounting for IL-10–induced TB susceptibility.
Activated B Cells Participating in the Anti-Myelin Response Are Excluded from the Inflamed Central Nervous System in a Model of Autoimmunity that Allows for B Cell Recognition of Autoantigen
Authors: Tesfagiorgis Yodit , Zhu Sarah L. , Jain Rajiv , Kerfoot Steven M. 
Published: June 2017

Abstract
Once activated, T cells gain the ability to access both healthy and inflamed nonlymphoid tissues. They are then reactivated to remain in the tissue and exert their effector function only if they encounter their specific Ag. In this study, we set out to determine if the same is true for B cells using a mouse model of CNS autoimmunity that incorporates both T and B cell recognition of a myelin autoantigen. Both T and B cells were common infiltrates of spinal cords in diseased mice. However, unlike T cells, anti-myelin B cells were excluded from the inflamed tissue. Further, CNS B cells did not have a phenotype consistent with Ag-specific activation as it occurs in lymphatic tissue. Instead, they expressed elevated levels of CD80, indicating that B cells may contribute to local inflammation through nonantigen-specific mechanisms.
Surgical Site Infections in a Rural Teaching Hospital of North India
Authors: Abbey Rajesh , Mohan Manjul , Malik Nitin , Tiwari Rohit , Nahar Shashank 
Published: June 2017

ABSTRACT

Aims and objectives
Surgical site infections (SSIs) are one of the most important causes of health care-associated infections. Understanding SSI reduces the social and economic burden of a hospital and society. In this context, we evaluated the various aspects of SSI in our institution, Rohilkhand Medical College & Hospital (RMCH), which is a tertiary care teaching hospital in rural Uttar Pradesh in North India.

Materials and methods
This prospective study was conducted in the Department of General Surgery, RMCH, Bareilly, Uttar Pradesh, India. A total number of 1,498 patients admitted for surgical procedures with effect from November 1, 2016 to December 31, 2016, formed the subjects of the present study. All operated cases during the above period, including major and minor, emergency and elective, laparoscopic and open procedures were included in the present study. Data so obtained were analyzed statistically. The Centers for Disease Control and Prevention, USA criteria were used for defining the wound. Sample swabs were collected from the first dressing and up to 2 to 4 weeks postoperatively. Samples were processed for aerobic and anaerobic flora, and the antibiotic sensitivity of the isolates was also performed.

Results and discussion
The SSI rate in the present study was 8.67%. Significantly higher incidence of SSI was detected with increasing age. The SSI rate in case of emergency surgeries was more (27.7%) as compared with routine/elective surgeries (6.3%). The higher incidence (18.75%) of SSI was detected in patients having preoperative hospital stay of more than 7 days, and the maximum incidence (15.7%) was observed in patients having longer postoperative hospital stay of more than 10 days. Dirty wounds had the highest incidence of SSI (53.45%). The incidence of SSI increased with duration of surgery, order of surgery, and with the increasing duration of postoperative drains. Staphylococcus aureus was the commonest isolate (32.30%) followed by Escherichia coli (39%).

Conclusion
Though the incidence of SSI in the present study was slightly low as compared with similar reports from other institutions of the country, more rational antibiotic policy and more stringent infection control measures are needed.

How to cite this article
Abbey RK, Mohan M, Malik N, Tiwari R, Nahar S. Surgical Site Infections in a Rural Teaching Hospital of North India. Int J Adv Integ Med Sci 2017;2(1):11-16.
Influence of urban pollution on the production of organic particulate matter from isoprene epoxydiols in central Amazonia
Authors: de Sá Suzane S. , Palm Brett B. , Campuzano-Jost Pedro , Day Douglas A. , Newburn Matthew K. , Hu Weiwei , Isaacman-VanWertz Gabriel , Yee Lindsay D. , Thalman Ryan , Brito Joel , Carbone Samara , Artaxo Paulo , Goldstein Allen H. , Manzi Antonio O. , Souza Rodrigo A. F. , Mei Fan , Shilling John E. , Springston Stephen R. , Wang Jian , Surratt Jason D. , Alexander M. Lizabeth , Jimenez Jose L. , Martin Scot T. 
Published: June 2017

Abstract. The atmospheric chemistry of isoprene contributes to the production of a substantial mass fraction of the particulate matter (PM) over tropical forests. Isoprene epoxydiols (IEPOX) produced in the gas phase by the oxidation of isoprene under HO2-dominant conditions are subsequently taken up by particles, thereby leading to production of secondary organic PM. The present study investigates possible perturbations to this pathway by urban pollution. The measurement site in central Amazonia was located 4 to 6 h downwind of Manaus, Brazil. Measurements took place from February through March 2014 of the wet season, as part of the GoAmazon2014/5 experiment. Mass spectra of organic PM collected with an Aerodyne Aerosol Mass Spectrometer were analyzed by positive-matrix factorization. One resolved statistical factor (IEPOX-SOA factor) was associated with PM production by the IEPOX pathway. The IEPOX-SOA factor loadings correlated with independently measured mass concentrations of tracers of IEPOX-derived PM, namely C5-alkene triols and 2-methyltetrols (R = 0. 96 and 0.78, respectively). The factor loading, as well as the ratio f of the loading to organic PM mass concentration, decreased under polluted compared to background conditions. For an increase in NOy concentration from 0.5 to 2 ppb, the factor loading and f decreased by two to three fold. Overall, sulfate concentration explained 37 % of the variability in the factor loading. After segregation of factor loading into subsets based on NOy concentration, the sulfate concentration explained up to 75 % of the variability. Considering both factors, the data sets show that the suppressing effects of increased NO concentrations dominated over the enhancing effects of higher sulfate concentrations. The pollution from Manaus elevated NOy concentrations more significantly than sulfate concentrations relative to background conditions. In this light, increased emissions of nitrogen oxides, as anticipated for some scenarios of Amazonian economic development, could significantly alter pathways of PM production that presently prevail over the tropical forest, implying changes to air quality and regional climate.
Osteopathic manipulative treatment: student attitudes before and after intensive clinical exposure
Authors: Magnus Warren W. , Gamber Russell G. 
Published: June 2017

Abstract
It is widely known that family practice osteopathic physicians actively use osteopathic manipulative treatment (OMT) as a part of their everyday practices, but many DOs in other specialty areas fail to use OMT at all. Physicians who use this modality often limit its use to musculoskeletal complaints. This pattern likely begins during undergraduate training at the time that OMT is taught. To warm student attitudes to OMT and provide a more integrated OMT training background, the University of North Texas Health Science Center at Fort Worth/Texas College of Osteopathic Medicine has added to the clinical curriculum a required 1-month rotation in manipulative medicine. With the rotation in place for a full academic year, it was important to determine the efficacy of the rotation curriculum. This assessment has been accomplished using a specialized protocol designed to gauge student attitudes and opinions regarding OMT, osteopathic medicine, and their own OMT skills.
Effect of maternal depression on premature infant health during initial hospitalization
Authors: Locke Robert , Baumgart Stephen , Locke Kenneth , Goodstein Mike , RN Claire Thies, , Greenspan Jay 
Published: June 2017

Abstract
This study evaluates the effect of maternal depression on neonatal health status in premature infants during their initial hospitalization. Infants younger than 34 weeks' gestation born to nondrug abusing mothers were enrolled in the study. Thirty-one mother-infant pairs were identified. Maternal depression was evaluated by the Center for Epidemiologic Studies-Depression Scale (CES-D). Scores ~ 16 defined maternal depression. Initial infant physiologic health status was determined by the Score for Neonatal Acute Physiology (SNAP). In-hospital health status was assessed by the following variables: days receiving supplemental oxygen, days on mechanical ventilation (VENT), and days not on enteral feeding (NPO). Health status variables evaluated for long-term outcome included bronchopulmonary dysplasia at 28 days (BPD), BPD at 34 weeks' postmenstrual age (BPD-34), and intraventricular hemorrhage (IVH). Seventeen (55%) of 31 mothers manifested depression on the CES-D. No epidemiologic differences were found between this group and the nondepressed mothers. No differences in gestation or birth weight was detected between the preterm infants of depressed versus nondepressed others. The CES-D scores correlated significantly with SNAP (r = .36, P < .02). Infants of depressed mothers experienced significantly worse outcomes in the occurrence of BPD (P = .015), BPD-34 (P = .049), and IVH (P = .055). This study confirms that maternal depression occurs frequently in mothers of preterm infants and adversely affects the presenting neonatal health status of their babies during the initial hospitalization. Maternal depression was related to the severity of the initial neonatal illness and was significantly related to IVH and BPD. These factors may have long-term consequences for subsequent growth, neurodevelopment, and recurrence of related health problems.
Sumatriptan-associated myocardial infarction: report of case with attention to potential risk factors
Authors: Pearlstein Louis , Abbrescia Vincent D. , Kotler Morris 
Published: June 2017

Abstract
Vascular headaches are a relatively common phenomenon. Increasing numbers of patients with headache are being considered for treatment with the selective serotonin-receptor agonist sumatriptan succinate because of its potential for pronounced therapeutic efficacy in selected patients. Sumatriptan-associated myocardial infarction occurred in a 50-year-old woman with a history of migraine headaches. Cardiac risk factors that must be considered in all patients with migraine before initiation of therapy include concomitant ergotamine use, postmenopausal state, male gender older than 40 years, family history of heart disease, cigarette smoking, hypertension, diabetes mellitus, as reviewed in this report.