bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pyrrolo[2,3‐b]pyridine Derivatives: Synthesis and Preliminary Evaluation of their Calf Thymus DNA Binding Properties
Authors: Singla Prinka , Luxami Vijay , Paul Kamaldeep 
Published: September 2016

AbstractBenzothiazole, benzimidazole and imidazopyridine promoted substitutions at C3 position of 1H‐pyrrolo[2,3‐b]pyridine have been reported. A new series of acylation as well as monoalkylation and dialkylation of 1H‐pyrrolo[2,3‐b]pyridine with different acyl and alkyl halides has been synthesized in moderate to good yields. Palladium catalyzed Suzuki‐Miyaura cross‐coupling has also been approached for the arylation at C6 position of imidazopyridine. Further, interaction studies of these compounds have been performed with calf thymus‐DNA using UV‐visible and fluorescence spectroscopic techniques. The effect of ionic strength and iodide, determined by absorption and emission spectra, supported the binding of compounds with ct‐DNA.
ZnO‐Porphyrin Composite Nanostructures as Discriminating Adducts for Metallic Ions in Aqueous Matrices
Authors: Giancane Gabriele , Bettini Simona , Pagano Rosanna , Valli Ludovico 
Published: September 2016

AbstractTetrapyrrolic macrocycles are largely used in the sensing of various analytes both in liquid and in gaseous phase, but the strong electronic delocalization of this class of molecules makes difficult to realize a selective active layer. To overcome this problem, in the present work it is proposed the synthesis of a supramolecular adduct of zinc oxide nanostructure and a free‐base tetra‐ pyridyl substituted porphyrin. The electronic structure of the two organic/inorganic compounds allows to observe a surface‐enhanced Raman scattering (SERS) of the porphyrin vibrational bands. This phenomenon is quenched by the presence of mercuric and cupric ions according to two different mechanisms monitored and explained by means of time resolved fluorescence spectroscopy. It was demonstrated that other substances in complex matrices, such as the food extracts, do not affect the electronic communication between ZnO and porphyrin preserving the SERS effect and minimizing the effect of interfering compounds.
Corinthians Arena – 2014 World Cup, design and construction
Authors: Stucchi Fernando , Coelho Ungaretti Marcelo , Fujii Gilson , Corres Peiretti Hugo , Soriano Martin José , Doniak Sérgio 
Published: September 2016

AbstractThis paper describes the design and construction of the concrete structures of the Corinthians Arena built for the 2014 World Cup. Due to many constraints, the structure was designed, essentially, with prefabricated structural concrete members, some specific elements were designed with structural concrete cast in situ, and some areas, with special construction problems, were designed with composite steel–concrete structures.
Proteomic and genomic characterization of a yeast model for Ogden syndrome
Authors: Dörfel Max J. , Fang Han , Crain Jonathan , Klingener Michael , Weiser Jake , Lyon Gholson J. 
Published: September 2016

AbstractNaa10 is an Nα‐terminal acetyltransferase that, in a complex with its auxiliary subunit Naa15, co‐translationally acetylates the α‐amino group of newly synthetized proteins as they emerge from the ribosome. Roughly 40–50% of the human proteome is acetylated by Naa10, rendering this an enzyme one of the most broad substrate ranges known. Recently, we reported an X‐linked disorder of infancy, Ogden syndrome, in two families harbouring a c.109 T > C (p.Ser37Pro) variant in NAA10. In the present study we performed in‐depth characterization of a yeast model of Ogden syndrome. Stress tests and proteomic analyses suggest that the S37P mutation disrupts Naa10 function and reduces cellular fitness during heat shock, possibly owing to dysregulation of chaperone expression and accumulation. Microarray and RNA‐seq revealed a pseudo‐diploid gene expression profile in ΔNaa10 cells, probably responsible for a mating defect. In conclusion, the data presented here further support the disruptive nature of the S37P/Ogden mutation and identify affected cellular processes potentially contributing to the severe phenotype seen in Ogden syndrome. Data are available via GEO under identifier GSE86482 or with ProteomeXchange under identifier PXD004923. © 2016 The Authors. Yeast published by John Wiley & Sons, Ltd.
Single‐Incision and Natural Orifice Translumenal Endoscopic Surgery in Switzerland
Authors: Steinemann Daniel C. , Zerz Andreas , Adamina Michel , Brunner Walter , Keerl Andreas , Nocito Antonio , Scheiwiller Andreas , Spalinger Rene , Vorburger Stephan A. , Lamm Sebastian H. 
Published: September 2016

AbstractBackgroundSingle‐incision laparoscopy (SIL) and natural orifice translumenal endoscopic surgery (NOTES) aim at reducing surgical access trauma. To monitor the introduction of emerging technologies, the Swiss Association for Laparo‐ and Thoracoscopic Surgeons launched a database in 2010. The current status of SIL and NOTES in Switzerland is reported, and the techniques are compared.MethodsThe number and type of procedures, surgeon experience, their impressions of performance, conversion, and complications between 2010 and 2015 are described. A survey was used to acquire additional data not included in the registry.ResultsNine centers included 650 procedures. Cholecystectomy (55 %) and sigmoidectomy (26 %) were most prevalent in both techniques. The number of active centers declined from 9 to 2 during the study period. The frequencies of taught procedures were 4 and 43 % for SIL and NOTES (p < 0.001), and surgeon self‐estimated impression of performance was perfect in 50 and 89 %, respectively (p < 0.0001). Conversions in total were 3.6 and 5.7 %, respectively, and 1.1 % to open for both techniques. Morbidity was 5 % in SIL and 2.7 % in NOTES, with 0.8 % access‐related complications in NOTES and none in SIL (p = 0.29). Of laparoscopic cholecystectomy, sigmoidectomy, and right hemicolectomy, 11.4 and 15.6 % of cases were operated using SIL or NOTES, respectively (p < 0.0001).ConclusionsAlthough in selected specialized centers, a considerable proportion of patients were treated using novel techniques, a fading interest of the surgical community in SIL and NOTES was observed. The proportion of SIL and NOTES procedures taught is insufficient and calls for improvement.
Comparison of AdipicVersusRenewable Azelaic Acid Polyester Polyols as Building Blocks in Soft Thermoplastic Polyurethanes
Authors: Mohd Noor Norhayati , Sendijarevic Aisa , Sendijarevic Vahid , Sendijarevic Ibrahim , Tuan Ismail Tuan Noor Maznee , Mohd Noor Mohd Azmil , Shoot Kian Yeong , Abu Hassan Hazimah 
Published: September 2016

AbstractIn this study, novel polyester diols of 2000 molecular weight (MW) were synthesized by reacting azelaic acid (AZ) with 1,3‐propanediol (1,3‐PDO) and diethylene glycol (DEG) in the esterification reaction catalyzed with a small amount of butyltintris(2‐ethylhexanoate). As a reference, polyester polyols of 2000 MW were synthesized from adipic acid (AA) with 1,3‐PDO and DEG. The properties of polyester polyols were evaluated. The polyester polyol based on AZ and 1,3‐PDO is 100 % renewable polyol; 1,3‐PDO used in the syntheses is renewable product produced by fermentation process of sugar. Both 1,3‐PDO‐polyester polyols exhibited crystalline transition above room temperature, while DEG‐polyester polyols were liquid at room temperature. The polyester polyols were chain‐extended with 4,4′‐diphenylmethane diisocyanate (Mondur M) and 1,4‐butanediol (BDO) to form thermoplastic polyurethanes (TPU). TPU were evaluated for mechanical and water resistance properties, and their morphology were studied via differential scanning calorimetry (DSC), Fourier transform infrared (FTIR), and atomic force microscope (AFM). TPU based on azelate and adipate polyols were relatively soft elastomeric materials with high melting temperatures. AFM analyses of TPU indicated better phase separation in 1,3‐PDO polyester polyols with the highest phase separation observed in TPU based on 1,3‐PDO/azelaic acid polyols. Water resistance of TPU based on azelate polyols was improved as compared to TPU based on adipate polyols.
The ordered assembly of tau is the gain‐of‐toxic function that causes human tauopathies
Authors: Goedert Michel 
Published: September 2016

AbstractA pathological pathway leading from soluble to insoluble and filamentous tau underlies human tauopathies. This ordered assembly causes disease and is the gain‐of‐toxic function. It involves the transition from an intrinsically disordered monomer to a highly structured filament. Based on recent findings, one can divide the ordered assembly into propagation of pathology and neurodegeneration. Short tau fibrils constitute the major species of seed‐competent tau in the brains of mice transgenic for human P301S tau. The molecular species of aggregated tau that are essential for neurodegeneration remain to be identified.
THE HOMOSEXUAL LIFESTYLE: TIME USE IN SAME-SEX HOUSEHOLDS
Authors: Martell Michael E. , Roncolato Leanne 
Published: September 2016

AbstractWe are among the first to use American time-use data to investigate non-market behavior in gay and lesbian households. We contribute to a literature that has documented a gay disadvantage and lesbian advantage in the labor market. Many have proposed that this pattern reflects, relative to their heterosexual counterparts, higher levels of household labor among gay men and lower levels of household labor among lesbian women. Results show that gay men, parents in particular, spend more time in household production than heterosexual men. We find evidence of different time-use patterns for lesbians, but they are driven by characteristics not sexual orientation. These results also contribute to the economics of the household showing that time use in same-sex households with weaker gender constructs does not conform to the predictions of models that highlight comparative advantage as a source of specialization.
Disaster Preparedness Among University Students in Guangzhou, China: Assessment of Status and Demand for Disaster Education
Authors: Tan Yibing , Liao Xiaolan , Su Haihao , Li Chun , Xiang Jiagen , Dong Zhaoyang 
Published: September 2016

AbstractObjectiveThis study had 2 aims. First, we evaluated the current levels of disaster preparedness among university students in southern China. Second, we assessed students’ demands for future disaster education. In addition, we examined the influence of demographic factors on current disaster preparedness status and demand.MethodsA cross-sectional design was used. The data were collected from 1893 students in 10 universities in the Guangzhou Higher Education Mega (GHEM) center. A self-administered questionnaire developed for this study was administered to assess the current status and demand for disaster education.ResultsThe results are based on 1764 valid questionnaires. Among the participants, 77.8% reported having had disaster education experiences before, 85.5% indicated their desire for a systematic disaster course, and 75.4% expressed their willingness to take such a course upon its availability. The total mean score for demand for disaster course content (5-point Likert scale) was 4.17±0.84, with items relating to rescue skills given the highest scores. These results suggested that students had high desires for disaster preparedness knowledge, especially knowledge concerning rescue skills. We observed significant differences in disaster education experiences between male and female students and across programs, school years, and home locations. Furthermore, we observed significant differences in demand for disaster course content between male and female students and across universities, student programs, years of school, and students’ majors.ConclusionA systematic disaster course focused on rescue skills is needed by all types of universities. To improve the disaster education system in universities, disaster drills should be performed on a semester basis as a refresher and to enhance disaster preparedness. The government and universities should support building a simulated disaster rescue center and recruit faculty from the emergency department, especially those who have had disaster relief experience. (Disaster Med Public Health Preparedness. 2017;11:310–317)
Diversity and creativity in cross-national teams: The role of team knowledge sharing and inclusive climate
Authors: Bodla Ali Ahmad , Tang Ningyu , Jiang Wan , Tian Longwei 
Published: September 2016

AbstractDiversity literature has demonstrated negative effects of surface-level diversity and positive effects of deep-level diversity. How do two types of diversity among cross national team members influence team knowledge sharing and team creativity? The purpose of this study is to explore conditions that leverage the positive and restrain the negative effects of team diversity on team knowledge sharing, which leads to team creativity. We expect inclusive climate as the significant condition and knowledge sharing as the profound intervening mechanism between team diversity and team creativity relationship. We tested the hypotheses with data from a sample of 60 cross-national research teams from several universities in China. The results support the hypothesized relationships among inclusive climate, team knowledge sharing, and team creativity. Our findings contribute to the advancement of team diversity and team creativity literature, and their theoretical and practical implications are discussed.
God’s Technicians: Religious Jurists and the Usury Ban in Judaism, Christianity, and Islam
Authors: Calder Ryan 
Published: September 2016

AbstractAt the heart of the $2 trillion Islamic-finance industry is a ban on interest. But why is there only anIslamicban on interest today? After all, for over a millennium, interest was also gravely sinful in Judaism and Christianity. While scholars have addressed the evolution of Jewish, Christian, and Islamic economic morality in isolation, very few since Weber have tackled the interest question directly and comparatively.I argue that the fate of the religious interest ban has always depended on the fate of religious jurists. When religious jurists are absent, no systematic interest ban emerges. When religious jurists emerge as technical experts, the interest ban appears and thrives. And when religious jurists come under attack or lose their traditional role in society, the interest ban withers and dies.To conclude, I call for a reconstruction of Weber’s theory of religion and economic morality that dissolves the tradition-modernity binary.
French Connections: The Reception of French Sociologists in the USA (1970-2012)
Authors: Ollion Etienne , Abbott Andrew 
Published: September 2016

AbstractThis paper examines the appropriation of French sociologists by US sociologists over the last four decades. Taking cues from scientometrics and from developments in the sociology of reception, it proposes a blueprint for the study of reception in times of mass digital data. Through this approach, the paper reveals two salient traits. First, out of the 200 authors of the sample, a small minority received considerable attention, while the others are virtually invisible. Second, when cited in the US, French authors are mobilized almost only as social theorists. The article then accounts for this peculiar reception by considering three levels: the intellectual structures of both fields, the local logics at play in the receiving field, and the “multiple lives” of a cited author.
Rethinking the Conflict “Resource Curse”: How Oil Wealth Prevents Center-Seeking Civil Wars
Authors: Paine Jack 
Published: September 2016

AbstractA broad literature on how oil wealth affects civil war onset argues that oil production engenders violent contests to capture a valuable prize from vulnerable governments. By contrast, research linking oil wealth to durable authoritarian regimes argues that oil-rich governments deter societal challenges by strategically allocating enormous revenues to enhance military capacity and to provide patronage. This article presents a unified formal model that evaluates how these competing mechanisms affect overall incentives for center-seeking civil wars. The model yields two key implications. First, large oil-generated revenues strengthen the government and exert an overall effect that decreases center-seeking civil war propensity. Second, oil revenues are less effective at preventing center-seeking civil war relative to other revenue sources, which distinguishes overall and relative effects. Revised statistical results test overall rather than relative effects by omitting the conventional but posttreatment covariate of income per capita, and demonstrate a consistent negative association between oil wealth and center-seeking civil war onset.
Forging Paths for the African Queer: Is There an “African” Mechanism for Realizing LGBTIQ Rights?
Authors: Devji Zahrah Z 
Published: September 2016

AbstractThe African continent has struggled to accept its LGBTIQ population and queer individuals continue to struggle in pursuit of their rights. Similar refrains justifying widespread homophobia reverberate throughout the continent. This article analyses two case studies in Africa: Uganda and South Africa. Although each country treats the question of queer rights differently, arguably the treatment of the queer on a day to day basis is not dissimilar in each country. The article considers whether there is a mechanism for realizing queer rights in Africa, by appealing to the values and cultures that exist on the continent.
No-tillage culture and nitrogen fertilizer management for burley tobacco production
Authors: ZOU C. , PEARCE R. C. , GROVE J. H. , COYNE M. S. 
Published: September 2016

SUMMARYFew studies have investigated nitrogen (N) fertilizer management in no-tillage (NT) tobacco (Nicotiana tobacumL.) production systems, even though N fertilization is known to influence tobacco cured leaf yield and quality. The present study evaluated how tillage practice and N fertilizer rate affected burley tobacco agronomic performance, plant available nitrogen (PAN) supply, and leaf chemical constituents. In 2012 and 2013, three N fertilizer rates (0, 140 and 280 kg N/ha) were introduced as split-plots within a long-term NT and conventional tillage (CT) (mouldboard plough) comparison study. Results (2007–2013) showed that the effect of tillage on tobacco yield depended on seasonal weather; NT tobacco appeared to have lower yield than CT tobacco in seasons with <450 mm growing season rainfall, but similar yields when rainfall was >500 mm. In 2012 (432 mm rainfall; 84% of the long-term seasonal mean), leaf SPAD reading, leaf nitrate concentration, total nitrogen concentration at the topping day (i.e. removal of flowers/buds at the tops of the plants) and cured leaf nicotine and alkaloid content suggested that N deficiency was more pronounced in NT than CT at the lowest N fertilizer rate. The PAN supply, as measured by a modifiedin situresin core method, was similar in 2012 between NT and CT, suggesting that plant factors may have had a role in N uptake efficiency. This scenario did not repeat in 2013 (706 mm rainfall; 137% of the long-term seasonal mean). Even though N fertilization rates were identical for both tillage practices in 2012 and 2013, PAN was lower, on average, in 2012. Because N uptake is largely the result of mass flow, the impact of reduced root density in NT tobacco would be expected to be more pronounced in a season such as 2012, when water was limited. Banding N close to the tobacco root system and/or side-dressing some portion of N may be recommended strategies to improve N use efficiency in NT burley tobacco production.
Therapeutic potential of the immunomodulatory proteins Wuchereria bancrofti L2 and Brugia malayi abundant larval transcript 2 against streptozotocin-induced type 1 diabetes in mice
Authors: Amdare N.P. , Khatri V.K. , Yadav R.S.P. , Tarnekar A. , Goswami K. , Reddy M.V.R. 
Published: September 2016

AbstractEpidemiological and experimental evidence has supported the concept of using helminths as alternative bio-therapeutic agents in the treatment of type 1 diabetes (T1D). In the current study, two filarial proteins, recombinant Wuchereria bancrofti L2 (rWbL2) and Brugia malayi abundant larval transcript 2 (rBmALT-2) have been investigated, individually and in combination, for their therapeutic potential in streptozotocin (STZ)-induced T1D. The rWbL2 and rBmALT-2 proteins, when administered individually or in combination, have resulted in lowering of the blood glucose levels and reducing the incidence of T1D in mice. In addition, these proteins have led to reduced lymphocytic infiltration and decreased islet damage and inflammation. The curative effect was found to be associated with the suppression of release of tumour necrosis factor-α (TNF-α) and interferon-γ (IFN-γ), and increased production of interleukin (IL)-4, IL-5 and IL-10 cytokines by the splenocytes of the diabetic mice. Insulin-specific IgG1 and antigen-specific IgE antibodies were found to be elevated in the sera of mice treated with rWbL2 and rBmALT-2 proteins. From the findings in this study, it can be envisaged that both of these filarial immunomodulatory proteins have the potential to ameliorate T1D by altering the regulatory immune responses.
A skink out of water: impacts of anthropogenic disturbance on an Endangered reptile in Australian highland swamps
Authors: Gorissen Sarsha , Greenlees Matthew , Shine Richard 
Published: September 2016

AbstractThe Blue Mountains water skinkEulamprus leuraensisis an Endangered swamp specialist known from < 60 sites and restricted to the rare, threatened and fragmented habitat of Temperate Highland Peat Swamps on Sandstone. Understanding the species’ ecology, notably its vulnerability to threatening processes such as hydrological disturbance, is essential if we are to retain viable populations of this Endangered reptile. We examined the impact of anthropogenic disturbance (longwall mining practices, development (industrial, urban, infrastructural) and damage by recreational vehicles) on this species, other herpetofauna and the swamp by surveying six paired undisturbed and disturbed sites in south-eastern Australia. The abundance ofE. leuraensiswas severely affected by disturbance. The species was absent from disturbed swamps, where it was replaced by its congenerE. heatwoleiand other woodland reptile species. Disturbance was associated with a halving of soil moisture content and a loss of surface water; the dense, live understorey was replaced by a sparser, drier habitat with dead vegetation, logs, rocks and bare ground. In effect, disturbance eliminated the distinctive features of the swamp habitat, transforming it into an area that resembled the surrounding habitat in terms of fauna, flora and physical characteristics. Our surveys suggest that hydrological disturbance (groundwater loss or alterations in surface water chemistry) extirpatesE. leuraensis. This species' dependence on groundwater renders it sensitive to habitat degradation through hydrological disturbance. The conservation message for management authorities is clear: to protect the skink, protect the habitat.
Text trajectories in a multilingual call centre: The linguistic ethnography of a calling script
Authors: Woydack Johanna , Rampton Ben 
Published: September 2016

AbstractCall centres have been widely criticised as standardised workplaces, and the imposition of calling scripts is often characterised as dehumanising and deskilling. But these accounts lack close analysis of how scripts are actually produced, taken up, and used by call-centre workers, and they are generally locked into dualistic analyses of control and resistance. In contrast, this article combines long-term ethnography with transcontextual analysis of the production, circulation and uptake of calling scripts. This reveals a good deal of collective and individual agency in processes of text-adaptation, and produces a rather more nuanced picture of work in a call centre. (Call centres, text trajectories, linguistic ethnography, standardisation)*