bluuebunny/crossref_metadata_2025_split huggingface dataset:
ІМУНОГІСТОХІМІЧНА ХАРАКТЕРИСТИКА СУБПОПУЛЯЦІЙ ЛІМФОЦИТІВ У СЕЛЕЗІНЦІ КУРЕЙ ПРИ ВАКЦИНАЦІЇ ЇХ ПРОТИ ІНФЕКЦІЙНОГО БРОНХІТУ
Authors: Guralska S.V. 
Published: October 2016

In the work the immunohistochemical characterization of subpopulations of СD4+, СD8+, CD45RA+ lymphocytes in the spleen of chickens vaccinated against infectious bronchitis clarified. Immunohistochemical studies have shown that changes in the clusters of immune cells after immunization was certain features in the spleen. Our studies showed that vaccination against infectious bronchitis of chickens in the first, 13 and 33, 83 and 103 day influenced on the change in the percentage of cells in the cluster of СD4+ (helper cells). So, after the introduction of the vaccine on the 8 th day, there was a tendency to increase to 9.23 ± 0,39% against 6,91 ± 0.26% in the control group. But at 20 days there was a significant increase in the number of helpers (of 10.07 ± 0,44% (p < 0.01) against 8.51 ± 0.31% in the control. Early supresion manifestations were recorded on 8th day. There has been a dramatic increase in the number of СD8+ in the experimental group, where the number of cells with the marker were higher than in control more than in two times. So, when studying subpopulations of lymphocyte marker СD8+ installed content control for 9.88 ± 0.38% in Chicks which received the vaccine in this period, the number of СD8+ amounted to 24.99 ± 0,46% (p < 0.001). On the 8th day there was a significant increase in the number of CD45RA+ to 14.22 ± 0.18% (p < 0.001), in control group this indicator amounted to 9.95 ± 0.38% Maximum increase observed on the 40th day, when the CD45RA+ in the group immunized chickens amounted to 14.74 ± 0.29% (p < 0.05).
АНАЛІЗ РИЗИКІВ ТА КРИТИЧНИХ КОНТРОЛЬНИХ ТОЧОК (НААСР), ПРИ ВИРОБНИЦТВІ М’ЯСНИХ КОВБАС НА ПП «CТРИЙСЬКІ ДЕЛІКАТЕСИ»
Authors: Dashkovskyy O. , Salata V. 
Published: October 2016

Meats include the main type of meat products. Great value and distribution of sausages due to their high nutritional valuation, calorie consumption opportunity without culinary processing a significant shelf life and the ability to transport over long distances. During the production of raw sausages remove parts that have low nutritional value (bones, connective tissue), and add substance to nutritionally valuable (dairy products, blood products, etc.) And have a good aroma and flavor properties (spices, etc.). Almost every food product that includes technology production element assembly recipes, can be attributed to the combination characteristic signs and indicators which will be determined in the primary content of the recipe specified product raw materials and manufacturing techniques. Therefore, in some countries, the products produced by the meat processing industry, classified on meat, meat combination, cereal (based on meat) and meat analogues. The main condition for the feasibility of achieving food remains its safety when consumed by man.The term "safety" means a guarantee that the full cycle of production, supply and storage of the product in terms not harm health.Article 20 of the Law of Ukraine «On the safety and quality of food» № 2809–IV of 6 September 2005 the requirement for persons engaged in the production or introduction into circulation of foodstuffs, apply sanitary measures and good practices of production, HACCP system and / or other systems to ensure safety and quality of food during the production and circulation of food. Almost all countries to food producers put forward similar demands.Due to possible prospects and expand markets, fatherland, his enterprises must increasingly implement certification system (security) product line with the recommendations of international legislation on the certification of food products (ISO 22000: 2005) systems Eurep GAP control in the crop, a system of control points for livestock and food production – hazard analysis critical control points (HACCP), which translates as «hazard analysis and critical control points». The main purpose of the article is the analysis of food safety, including cooked sausages, analysis of the presence of hazards throughout the production chain link on the example P.C. «SMIO» «Stryjsky meats delicious».
ВПЛИВ КОРМОВИХ ДОБАВОК НА ПРОДУКТИВНІСТЬ, ГЕМАТОЛОГІЧНІ ТА ІМУНОЛОГІЧНІ ПОКАЗНИКИ КРОВІ КУРЧАТ–БРОЙЛЕРІВ
Authors: Kotsumbas H.I. , Hryniv М.І. 
Published: October 2016

The results of the influence of feed additives: acidulent Versal liquid and probiotic bifidobacteria PKB on the growth dynamics and some hematological and immunological parameters of broiler chickens are presented in this article. The research was conducted on 30 broiler chicks. There were formed 3 groups. There were 10 chicks in each of them: a control group didn't get any feed additives; 1–st experimental group got feed and acidulent Versal liquid solution at the recommended dose of 1 ml /1 l of water; 2–nd experimental group got feed with probiotics bifidobacteria PKB at the recommended dose of 1g / 1kg of feed and acidulent Versal liquid solution at the recommended dose of 1 g/1 l of water. The 15th and 30th day blood were collected for hematological and immunological parameters checking.It was found, chicks that have got feed additives achieved more intensive increasing of average live weight and daily gain during this period. The live weight of broiler chicks from the second experimental group was higher at 76.5 grams, compared with the control and the 136.6 h – compared with I research group in case of using acidified and probiotics bifidobacteria. Average daily increasing were 49.93 g in the control group, 48.21 g and 52.36 g according to another experimental groups. There was a tendency of hemoglobin increasing on the 30–th day of experiment in all experimental groups. The hemoglobin concentration increased by 1.09 times in the 1–st group and in 1,20 times in the 2–nd group. The number of leukocytes was increased in the experimental group. It was also increased by 16.6% in the 1–st group and by 44.4% in the 2–nd group. Phagocytic activity of pseudo eosinophils increased in all experimental groups on the 30–th day of the feed additives using. The most important increasing by 7.2% was in the 2–nd group. There was also a tendency of the phagocytic index increasing in all experimental groups of chicks on the 30–th day of this investigation. It was established that the using of acidulent and PKB probiotic preparation of food at feeding broilers improves hemoglobin levels. It also promotes to leukocytosis, phagocytic pseudo eosinophils activity and improves the overall condition and immunological reactivity.
ЕТІОЛОГІЧНІ ЧИННИКИ МАСТИТІВ КОРІВ УКРАЇНСЬКОЇ ЧОРНО–РЯБОЇ МОЛОЧНОЇ ПОРОДИ
Authors: Panevnyk V. , Suprovych T. 
Published: October 2016

The article shows data on the microbial landscape and quantity of somatic cells milk in different forms of mastitis in cows. Index number of somatic cells (SCC) in the raw milk of cows in the country is only used to establish the quality milk. They are key safety indicators that are directly related to udder cow disease, especially subclinical mastitis. Research has established that the number of SCC in healthy animals ranges from 84000 cells/ml to 436000 cells/ml. Over the course of subclinical turned from 508000 cells/ml to 756000 cells/ml. Animals with clinical form of mastitis were from 876000 cells/ml to 69260000 cells/ml. The 42 cows of the first lactation average SCC was 143000 cells/ml, and 47 of fifth lactation cows – 213000 cells/ml.The microflora in the breast can get in different ways: galactogenous – through teat channel hematogenous ahd lymphogenous ways. The leading role galactogenous way in which the pathogens penetrate from the environment through teat channel. This contributes to the udder skin contamination by microorganisms. Activators of subclinical mastitis were Staphylococcus aureus 31.8% and Streptococcus agalactiae 40.9%. In the clinical course of mastitis major pathogens were Escherichia coli – 34.8% and Staphylococcus aureus – 41.3%. Selected cultures of microorganisms were sensitive to cephalexin, gentamicin, oxacillin, rifampicin, enrofloksacin.
Characterizing Spatial–Temporal Changes of Soil and Crop Parameters for Precision Management in a Coastal Rainfed Agroecosystem
Authors: Yao R. J. , Yang J. S. , Wu D. H. , Xie W. P. , Gao P. , Wang X. P. 
Published: October 2016

Understanding the intrinsic relationship between highly varied crop productivity and soil characteristics is essential for developing site‐specific management practices. Our primary objectives were to quantify the temporal variation of soil attributes and crop productivity, to characterize the spatiotemporal variability and to delineate management zones of crop productivity for precision management. A pool of 12 soil properties (0–15 cm) and crop annual output (CAO) were collected annually from corn (Zea mays L.)–barley (Hordeum vulgare L.) rotation for three consecutive years in a coastal rainfed agroecosystem of East China. Results indicated that varying degrees of sustained temporal increase were observed for percentage of clay particles (CL), soil organic carbon (SOC), available nitrogen (AN), and CAO, whereas electrical conductivity of saturated soil paste extract (ECe), sodium adsorption ration (SAR) and soil available potassium (AK) declined continuously. The ECe and SOC had the largest negative and positive contribution to CAO, respectively. An overall increasing trend was observed for CL, SOC, and CAO whereas ρb and ECe decreased over the 3‐yr period. Followed by CAO and SOC, soil ECe had the lowest degree of temporal stability, and ρb and CL had the highest degrees of temporal stability. Separating the experimental site into two management zones effectively discriminated the spatial variability of crop and soil and reduced the necessary sampling volume. It is concluded that the spatial and temporal coherence of soil and crop parameters can be successfully used to develop site‐specific management zones and reduce sampling efforts for precision management.Core Ideas

Percentage of clay particles, soil organic carbon, and crop annual output increased while soil bulk density and electrical conductivity of saturated soil paste extract decreased over the 3‐yr period.
Electrical conductivity of saturated soil paste extract showed temporal instability, and soil bulk density and percentage of clay particles exhibited temporal stability.
Separating the field into two management zones proved to be a good compromise.
The two management zones contributed to reducing sampling efforts.
Comparative account of allelopathic potential of essential oil of Tagetes minuta L. and its major component cis-β-Ocimene
Authors: Arora* Komal , Batish Daizy , Singh Harminder Pal , Kohli Ravinder Kumar 
Published: October 2016

The study aims to explore the chemical composition of volatile essential oil of Tagetes minuta and comparison of its allelopathic potential with cis-β-ocimene, a major component of oil. T. minuta L. is an exotic aromatic plant found growing in northern plains and western Himalayas in India. The water distilled essential oil from aerial parts of T. minuta (at flowering stage) was analyzed by GC-MS. The analysis revealed 27 compounds representing 95.73% of the oil. cis-b-Ocimene (44.56%), dihydrotagetone (28.52%), limonene (3.99%) and tagetone (7.42%) were its major compounds. A comparison of allelopathic effect of cis-b-ocimene was made with T. minuta oil using Cassia occidentalis L., a common wasteland weed, as test plant. Laboratory study included growth studies in the form of germination, seedling length and dry weight of test plant under both treatments i.e. T. minuta oil and cis-b-ocimene. The inhibitory effect of ocimene was more significant as compared to oil. However, highest concentration (20µg/cc) of both treatments was found to be inhibitory with respect to all parameters.
COMPARATIVE CHARACTERISTICS OF THE BONE MARROW FROM FEMORAL HEAD AND ILIAC BONE IN PATIENS WITH FEMORAL NECK FRACTURES
Authors: Borovkova N. V. , Malygina M. A. , Ponomarev I. N. , Sakharova O. M. 
Published: October 2016

Increasing number of elderly patients with femoral neck fractures requires a search for an optimal treatment regimen based on a natural sustenance and regulation mechanisms of bone homeostasis.Purpose of the study – to perform a comparative cellularity analysis of bone marrow obtained from femoral neck and iliac bone of elderly patients.Material and methods. The experimental group included 29 patients with closed fractures of femoral neck, injured by falling on the side from a standing position. Bone marrow was obtained from femoral neck and iliac bone during procedure of screw internal fixation or hip replacement. In the control group, the authors used bone marrow harvested from the same anatomical areas of 10 cadaveric donors. Nucleated cells (NCs), hematopoietic stem cells (HSCs) and multipotent mesenchymal stem cells (MSCs) were counted in bone marrow by flow cytometry.Results. Comparative study demonstrated that bone marrow from the hip of patients with fractures and cadaveric donors contained less concentration of NCs and HSCs than bone marrow from the ilium. However, the difference in concentration was significant only in the experimental group. At the same time, in patients with fractures the NCs concentration and absolute content of HSCs in bone marrow obtained from hip was significantly lower than those from cadaveric donors. Meanwhile, samples obtained from the iliac bone in the experimental and control groups had no significant difference. The authors also observed that concentration of HSCs and MSCs in the bone marrow from male hips was significantly lower than in females. As a result, male patients with fractures demonstrated difference in concentrations of HSCs samples from ilium and femoral neck reaching 84.6%, MSCs – 86.6%; females demonstrated differences of 68.9% and 69.2% respectively.Discussion. The data collected allows suggesting that one of the main factor violating micro-architecture of bone and in development of osteoporosis is an alteration in the cellular composition of bone marrow. While MSCs are active in regeneration of bone tissue, increase in their concentration in the fracture zone can stimulate the healing. Thus, to improve treatment outcomes in patients with hip fractures after internal fixation with cannulated screws, it could be beneficial to use grafting of autologous bone marrow obtained from the iliac bone featured by a higher stem cells concentration.
The Intersection of “Bad Apples,” “Bad Barrels,” and the Enabling Use of Performance Measurement Systems
Authors: Burney Laurie L. , Radtke Robin R. , Widener Sally K. 
Published: October 2016

ABSTRACT
A performance measurement system (PMS) consists of data transformed into performance measures, which is used to control operations and employee behavior. As such, a PMS is embedded within the broader accounting information system (AIS). Existing literature suggests organizations benefit from using a PMS in a way that employees perceive enables them to better perform their job tasks. However, those benefits may not always be realized depending on individual and unit-level ethical characteristics that interact with the use of AIS. The purpose of this study is to examine the intersection of AIS and business ethics by focusing on how a specific type of AIS is used; namely, the PMS. We integrate the extent of perceived amoral manipulation and the ethical work climate with the extent to which the PMS is perceived to be enabling. We document instances when the enabling use of a PMS is not always beneficial, offer implications for organizations in terms of managing the level of counterproductive work behaviors when using enabling control, and provide directions for future research.
Belgian class II nuclear facilities such as irradiators and accelerators: Regulatory Body attention points and operating experience feedback
Authors: Minne E. , Carlier P. , Peters C. , Mommaert C. , Kennes C. , Cortenbosch G. , Schmitz F. , Van Haesendonck M. , Schrayen V. , Wertelaers A. 
Published: October 2016

Abstract
The aim of this paper is to present the Regulatory Body attention points and the operating experience feedback from Belgian “class IIA” facilities such as industrial and research irradiators, bulk radionuclides producers and conditioners. Reinforcement of the nuclear safety and radiation protection has been promoted by the Federal Agency for Nuclear Control (FANC) since 2009. This paper is clearly a continuation of the former paper [1] presenting the evolution in the regulatory framework relative to the creation of Bel V, the subsidiary of the FANC, and to the new “class IIA” covering heavy installations such as those mentioned above. Some lessons learnt are extracted from the operating experience feedback based on the events declared to the authorities. Even though a real willingness to meet the new safety requirements is observed among the “class IIA” licensees, promoting the safety culture, the nuclear safety and radiation protection remains an endless challenge for the Regulatory Body.
Assessing reactor physics codes capabilities to simulate fast reactors on the example of the BN-600 Benchmark
Authors: Ivanov V. , Bousquet J. 
Published: October 2016

Abstract
This work aims to assess the capabilities of reactor physics codes (initially validated for thermal reactors) to simulate fast sodium cooled reactors. The BFS-62-3A critical experiment from the BN-600 Hybrid Core Benchmark Analyses was chosen for the investigation. Monte-Carlo codes (KENO from SCALE and SERPENT 2.1.23) and the deterministic diffusion code DYN3D-MG are applied to calculate the neutronic parameters. It was found that the multiplication factor and reactivity effects calculated by KENO and SERPENT using the ENDF/B-VII.0 continuous energy library are in a good agreement with each other and with the measured benchmark values. Few-groups macroscopic cross sections, required for DYN3D-MG, were prepared in applying different methods implemented in SCALE and SERPENT. The DYN3D-MG results of a simplified benchmark show reasonable agreement with results from Monte-Carlo calculations and measured values. The former results are used to justify DYN3D-MG implementation for sodium cooled fast reactors coupled deterministic analysis.
Decommissioning of the pool reactor Thetis in Ghent, Belgium
Authors: Cortenbosch G. , Mommaert C. , Thierens H. , Monsieurs M. , Meirlaen I. , Strijckmans K. 
Published: October 2016

Abstract
The Thetis research pool reactor (with a nominal power of 150 kW) of the Ghent University was operational from 1967 till December 2003. The first phase of the decommissioning of the reactor, the removal of the spent fuel from the site, took place in 2010. The cumulative dose received was only 404 man · μSv. During the second phase, the transition period between the removal of the spent fuel in 2010 and the start of the decommissioning phase in March 2013, 3-monthly internal inspections and inspections by Bel V, were performed. The third and final decommissioning phase started on March 18, 2013. The total dose received between March 2013 and August 2013 was 1561 man · μSv. The declassification from a Class I installation to a Class II installation was possible by the end of 2015. The activated concrete in the reactor pool will remain under regulatory control until the activation levels are lower than the limits for free release.
Lessons learned on probabilistic methodology for precursor analyses
Authors: Babst S. , Gänssmantel G. , Wielenberg A. 
Published: October 2016

Abstract
Based on its experience in precursor assessment of operating experience from German NPP and related international activities in the field, GRS has identified areas for enhancing probabilistic methodology. These are related to improving the completeness of PSA models, to insufficiencies in probabilistic assessment approaches, and to enhancements of precursor assessment methods. Three examples from the recent practice in precursor assessments illustrating relevant methodological insights are provided and discussed in more detail. Our experience reinforces the importance of having full scope, current PSA models up to Level 2 PSA and including hazard scenarios for precursor analysis. Our lessons learned include that PSA models should be regularly updated regarding CCF data and inclusion of newly discovered CCF mechanisms or groups. Moreover, precursor classification schemes should be extended to degradations and unavailabilities of the containment function. Finally, PSA and precursor assessments should put more emphasis on the consideration of passive provisions for safety, e. g. by sensitivity cases.
Lapatinib, trastuzumab or the combination added to neoadjuvant chemotherapy for breast cancer
Authors: Liang Quan , Fu Qiang , Li Wei , You Jiacong , Zhao Zhanchao 
Published: October 2016

<p>The aim of this study was to compare the efficacy and safety of trastuzumab versus the combination of trastuzumab and lapatinib added to neoadjuvant chemotherapy for HER2 positive breast cancer. PubMed, MEDLINE, The Cochrane Library, Web of Science and nearly 5 years of the important international conference on oncology records were searched for randomized clinical trials that compared lapatinib plus trastuzumab and neoadjuvant chemotherapy (NAC) with trastuzumab in combination with NAC and that included pathologic complete response rate as the primary outcome. Finally, 6 clinical randomized controlled trials were included. Meta-analysis shows that pathological complete response rate was significantly increased in trastu-zumab plus lapatinib group than single use trastuzumab group (53.4%, 40.4%, RR = 1.75, 95% CI 1.38 ~ 2.23, p&lt;0.001). In conclusion, the combination of trastuzumab and lapatinib added to neoadjuvant chemotherapy in HER2 positive breast cancer is more effective.</p><p> </p>
RESOLVING CLOSE ENCOUNTERS: STABILITY IN THE HD 5319 AND HD 7924 PLANETARY SYSTEMS
Authors: Kane Stephen R. 
Published: October 2016

ABSTRACT
Radial velocity searches for exoplanets have detected many multi-planet systems around nearby bright stars. An advantage of this technique is that it generally samples the orbit outside of the inferior/superior conjunction, potentially allowing the Keplerian elements of eccentricity and argument of periastron to be well characterized. The orbital architectures for some of these systems show signs of close planetary encounters that may render the systems unstable as described. We provide an in-depth analysis of two such systems: HD 5319 and HD 7924, for which the scenario of coplanar orbits results in their rapid destabilization. The poorly constrained periastron arguments of the outer planets in these systems further emphasizes the need for detailed investigations. An exhaustive scan of parameter space via dynamical simulations reveals specific mutual inclinations between the two outer planets in each system that allow for stable configurations over long timescales. We compare these configurations with those presented by mean-motion resonance as possible stability sources. Finally, we discuss the relevance to interpretation of multi-planet Keplerian orbits and suggest additional observations that will help to resolve the system stabilities.