bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does finance solve the supply chain financing problem?
Authors: Caniato Federico , Gelsomino Luca Mattia , Perego Alessandro , Ronchi Stefano 
Published: September 2016

PurposeRecently, in response to the credit crunch and the increased costs of financing, new solutions for supporting the financial management of supply chains, known as supply chain finance (SCF), have been developed. They exploit the strengths of supply chain links to optimise working capital. The purpose of this paper is to provide a reference framework that links together the objectives leading to the adoption of SCF solutions and several moderating variables.Design/methodology/approachThis paper adopts a multiple case study methodology, analysing 14 cases of the application of SCF solutions among Italian companies.FindingsThe main findings are the identification of the different objectives leading to the adoption of SCF; the analysis of the impact of moderating variables (the level of inter- and intra-firm collaboration, the level of the trade process digitalisation and the bargaining power and financial strength of the leading firm) on SCF adoption; and the formulation of a reference framework supporting the effective adoption of SCF solutions.Research limitations/implicationsThis contribution is exploratory in nature; theory-testing contributions should be the focus of further research. Also, the sample is limited to Italian companies. Finally, the service provider’s point of view has been marginally taken into consideration in this study.Originality/valueThe article addresses the need for more empirical research on SCF. It provides a reference framework focused on the objectives and moderating variables leading to effective SCF adoption, providing a theory-building contribution on the general topic of SCF and on the specific topic of the adoption process of different SCF solutions.
Specialized or opportunistic—how does the high mountain endemic butterfly Erebia nivalis survive in its extreme habitats?
Authors: Ehl Stefan , Dalstein Vivian , Tull Fabienne , Gros Patrick , Schmitt Thomas 
Published: September 2016

AbstractHigh mountain ecosystems are a challenge for the survival of animal and plant species, which have to evolve specific adaptations to cope with the prevailing extreme conditions. The strategies to survive may reach from opportunistic to highly adapted traits. One species successfully surviving under these conditions is the here studied butterfly Erebia nivalis. In a mark‐release‐recapture study performed in the Hohe Tauern National Park (Austria) from 22 July to 26 August 2013, we marked 1386 individuals and recaptured 342 of these. For each capture event, we recorded the exact point of capture and various other traits (wing conditions, behavior, nectar sources). The population showed a partial protandrous demography with the minority of males emerging prior to the females, but the majority being synchronized with them. Males and females differed significantly in their behavior with males being more flight active and females nectaring and resting more. Both sexes showed preferences for the same plant species as nectar sources, but this specialization apparently is the result of a rapid individual adaptation to the locally available flowers. Estimates of the realized dispersal distances predicted a comparatively high amount of long‐distance flights, especially for females. Therefore, the adaptation of Erebia nivalis to the unpredictable high mountain conditions might be a mixture of opportunism and specialized traits.
Audit of the dietetic care of patients with type 1 diabetes at a large Australian paediatric tertiary hospital and comparison with the International Society for Paediatric and Adolescent Diabetes nutrition guidelines
Authors: Battersby Rachel , Sweeney Annabel , Toome Sarah , Fairchild Janice , Miller Jacqueline 
Published: September 2016

AimOptimal glycaemic control is important in children and adolescents with type 1 diabetes (T1D) to reduce the risk of developing microvascular complications. Modest reductions in HbA1c translate to significant risk reductions of these complications. Research indicates that targeted dietetic care using evidence‐based guidelines improves HbA1c levels. The aim of this study was to audit the dietetic care provided to patients with T1D at the Women's and Children's Hospital (WCH) and compare the service provided to the International Society for Paediatric and Adolescent Diabetes (ISPAD) nutrition guidelines.MethodsA retrospective medical records audit of the dietetic service was conducted on 410 (99% of eligible) patients who attended the WCH Diabetes Outpatient Clinic between 1 January 2010 and 30 June 2013. These data were then compared to the ISPAD nutrition guidelines, with a focus on the key service delivery targets.ResultsOf the newly diagnosed patients (n = 128), 100% received initial dietary advice by a paediatric diabetes dietitian; 61% of these patients then received a follow‐up appointment within one month of diagnosis. Of those who were >1 year post‐diagnosis (n = 389), only 6% were seen annually; 79% of patients were identified with a condition requiring more frequent review, of whom 23% were seen more frequently.ConclusionsThis large and comprehensive audit, conducted for a 3.5‐year period, has shown that the dietetic care of newly diagnosed children and adolescents is mostly in line with ISPAD guidelines, but there is suboptimal follow‐up after diagnosis.
Characterization of Chemically and Thermally Treated Oil‐in‐Water Heteroaggregates and Comparison to Conventional Emulsions
Authors: Maier Christiane , Reichert Corina L. , Weiss Jochen 
Published: September 2016

AbstractHeteroaggregated oil‐in‐water (O/W) emulsions formed by targeted combination of oppositely charged emulsion droplets were proposed to be used for the modulation of physical properties of food systems, ideally achieving the formation of a particulate 3‐dimensional network at comparably low‐fat content. In this study, rheological properties of Quillaja saponins (QS), sugar beet pectin (SBP), and whey protein isolate (WPI) stabilized conventional and heteroaggregated O/W emulsions at oil contents of 10% to 60% (w/w) were investigated. Selected systems having an oil content of 30% (w/w) and different particle sizes (d43 ≤ 1.1 or ≥16.7 μm) were additionally subjected to chemical (genipin or glutaraldehyde) and thermal treatments, aiming to increase network stability. Subsequently, their rheological properties and stability were assessed. Yield stresses (τ0) of both conventional and heteroaggregated O/W emulsions were found to depend on emulsifier type, oil content, and initial droplet size. For conventional emulsions, high yield stresses were only observed for SBP‐based emulsions (τ0,SBP approximately 157 Pa). Highest yield stresses of heteroaggregates were observed when using small droplets stabilized by SBP/WPI (approximately 15.4 Pa), being higher than those of QS/WPI (approximately 1.6 Pa). Subsequent treatments led to significant alterations in rheological properties for SBP/WPI systems, with yield stresses increasing 29‐fold (glutaraldehyde) and 2‐fold (thermal treatment) compared to untreated heteroaggregates, thereby surpassing yield stresses of similarly treated conventional SBP emulsions. Genipin‐driven treatments proved to be ineffective. Results should be of interest to food manufacturers wishing to design viscoelastic food emulsion based systems at lower oil droplet contents.
Effects of Accelerated Storage on the Quality of Kenaf Seed Oil in Chitosan‐Coated High Methoxyl Pectin‐Alginate Microcapsules
Authors: Leong Mei‐Huan , Tan Chin‐Ping , Nyam Kar‐Lin 
Published: September 2016

AbstractThe objective of this research was to study the oxidative stability and antioxidant properties of microencapsulated kenaf (Hibiscus cannabinus L.) seed oil (MKSO) produced by co‐extrusion technology upon accelerated storage. The combination of sodium alginate, high methoxyl pectin, and chitosan were used as shell materials. The oxidative stability of the kenaf seed oil was determined by iodine value, peroxide value, p‐Anisidine value, total oxidation (TOTOX), thiobarbituric acid reactive substances assay, and free fatty acid content. Total phenolic content, 2,2′‐azino‐bis(3‐ethylbenzothiazoline‐6‐sulphonic acid) cation radical‐scavenging assay and 2,2‐diphenyl‐1‐picrylhydrazyl radical scavenging assay were used to examine the antioxidant properties of oils. Oxidative stability tests showed that bulk kenaf seed oil (BKSO) was oxidized significantly higher (P < 0.05) than MKSO. The total increment of TOTOX value of BKSO was 165.93% significantly higher (P < 0.05) than MKSO. Co‐extrusion technology has shown to be able to protect kenaf seed oil against lipid oxidation and delay the degradation of natural antioxidants that present in oil during storage.
Annexin A1 restores Aβ1‐42‐induced blood–brain barrier disruption through the inhibition of RhoA‐ROCK signaling pathway
Authors: Park Jong‐Chan , Baik Sung Hoon , Han Sun‐Ho , Cho Hyun Jin , Choi Hyunjung , Kim Haeng Jun , Choi Heesun , Lee Wonik , Kim Dong Kyu , Mook‐Jung Inhee 
Published: September 2016

SummaryThe blood–brain barrier (BBB) is composed of brain capillary endothelial cells and has an important role in maintaining homeostasis of the brain separating the blood from the parenchyma of the central nervous system (CNS). It is widely known that disruption of the BBB occurs in various neurodegenerative diseases, including Alzheimer's disease (AD). Annexin A1 (ANXA1), an anti‐inflammatory messenger, is expressed in brain endothelial cells and regulates the BBB integrity. However, its role and mechanism for protecting BBB in AD have not been identified. We found that β‐Amyloid 1‐42 (Aβ42)‐induced BBB disruption was rescued by human recombinant ANXA1 (hrANXA1) in the murine brain endothelial cell line bEnd.3. Also, ANXA1 was decreased in the bEnd.3 cells, the capillaries of 5XFAD mice, and the human serum of patients with AD. To find out the mechanism by which ANXA1 recovers the BBB integrity in AD, the RhoA‐ROCK signaling pathway was examined in both Aβ42‐treated bEnd.3 cells and the capillaries of 5XFAD mice as RhoA was activated in both cases. RhoA inhibitors alleviated Aβ42‐induced BBB disruption and constitutively overexpressed RhoA‐GTP (active form of RhoA) attenuated the protective effect of ANXA1. When pericytes were cocultured with bEnd.3 cells, Aβ42‐induced RhoA activation of bEnd.3 cells was inhibited by the secretion of ANXA1 from pericytes. Taken together, our results suggest that ANXA1 restores Aβ42‐induced BBB disruption through inhibition of RhoA‐ROCK signaling pathway and we propose ANXA1 as a therapeutic reagent, protecting against the breakdown of the BBB in AD.
Chelation of hippocampal zinc enhances long‐term potentiation and synaptic tagging/capture in CA1 pyramidal neurons of aged rats: implications to aging and memory
Authors: Shetty Mahesh Shivarama , Sharma Mahima , Sajikumar Sreedharan 
Published: September 2016

SummaryAging is associated with decline in cognitive functions, prominently in the memory consolidation and association capabilities. Hippocampus plays a crucial role in the formation and maintenance of long‐term associative memories, and a significant body of evidence shows that impairments in hippocampal function correlate with aging‐related memory loss. A number of studies have implicated alterations in hippocampal synaptic plasticity, such as long‐term potentiation (LTP), in age‐related cognitive decline although exact mechanisms underlying are not completely clear. Zinc deficiency and the resultant adverse effects on cognition have been well studied. However, the role of excess of zinc in synaptic plasticity, especially in aging, is not addressed well. Here, we have investigated the hippocampal zinc levels and the impairments in synaptic plasticity, such as LTP and synaptic tagging and capture (STC), in the CA1 region of acute hippocampal slices from 82‐ to 84‐week‐old male Wistar rats. We report increased zinc levels in the hippocampus of aged rats and also deficits in the tetani‐induced and dopaminergic agonist‐induced late‐LTP and STC. The observed deficits in synaptic plasticity were restored upon chelation of zinc using a cell‐permeable chelator. These data suggest that functional plasticity and associativity can be successfully established in aged neural networks by chelating zinc with cell‐permeable chelating agents.
First record of a possible predatory collembolan species, Dicyrtoma fusca (Collembola: Dicyrtomidae), in New Zealand
Authors: Greenslade Penelope , Boyer Stephane , Shields Morgan W , Wratten Steve D 
Published: September 2016

AbstractSpecimens of a previously unrecorded collembolan species were found in a field margin of a commercial dairy farm near Christchurch, New Zealand. They were consistently observed apparently feeding on egg batches of the light brown apple moth Epiphyas postvittana, which were being used as bait to assess predation rate by potential biocontrol agents. The collembolan specimens were identified as the European species Dicyrtoma fusca based on published morphological descriptions of this species. DNA sequence data of the New Zealand specimens clustered with sequence data from GenBank of this species from Norway and England, confirming that D. fusca populations in New Zealand originated from Europe. A GenBank sequence had previously identified a collembolan species from Estonia as this species, but its position in the phylogeny indicates that it is a different species. Some morphological variations observed in arrangement of macrochaetae on the head were shown by sequence data to be intraspecific differences only.
Relationship between serum testosterone and nocturia in men without benign prostate enlargement
Authors: Jeh S. U. , Yoon S. , Seo D. H. , Lee S. W. , Lee C. , Choi S. M. , Kam S. C. , Hwa J. S. , Chung K. H. , Hyun J. S. 
Published: September 2016

SummaryRecent studies have focused on the relationship between nocturia and serum testosterone because testosterone is thought to be an important factor of prostate growth. However, it remains unclear whether altered serum concentrations of testosterone is associated with an increased risk of nocturia because patients who were taking diuretics or who had a large prostate, which may precipitate nocturia, were not excluded from most previous studies. We analyzed the clinical records of 596 non‐benign prostatic enlargement (BPE) male patients to explore the relationship between serum total testosterone and nocturia. All patients were evaluated using a serum prostate‐specific antigen (PSA) assay, measurement of serum total testosterone, transrectal ultrasonography, uroflowmetry, and a compilation of the International Prostate Symptom Score (IPSS) and International Index of Erectile Function (IIEF) questionnaires. Nocturia was defined as ≥2 nocturnal voiding episodes. The number of nocturia episodes was assessed using IPSS question 7. To evaluate the effect of serum testosterone on nocturia, multivariate regression analysis was performed including the covariates of age, IPSS, IIEF score, body mass index, PSA, prostate volume, and maximal urine flow rate. Based on multivariate linear analysis, serum testosterone level was not significantly associated with the severity of nocturia. However, with regard to the relationship between prevalence of nocturia and serum testosterone, prevalence of nocturia was significantly positively associated with age (OR = 1.048, p = 0.005), total IPSS (OR = 1.217, p < 0.001), and testosterone level (OR = 1.150, p = 0.041). Therefore, in men without an enlarged prostate, testosterone may play an opposing role in the etiology of nocturia.
The Revitalization of Yajé Shamanism among the Siona: Strategies of Survival in Historical Context
Authors: Langdon Esther Jean 
Published: September 2016

AbstractThis article outlines the transformations of yajé shamanism among the Siona Indians of the Northwest Amazon Basin of Colombia. The shaman's role and the political and sacred use of yajé rituals have changed since colonial times and can be seen as a result of adaptive strategies for survival. This study examines the factors that have contributed to the current revitalization due to state and popular representations of the ecological and wise Indian. Although Gow and Taussig argue that ayahuasca shamanism in Peru and folk healing in Colombia rose out of colonial domination and proletarian concerns, Siona shamanic practices are best understood as a transfiguration and result of their particular response to outside forces. Their contemporary use of yajé reflects this past and the discourse, aesthetics, expectations, and demands of the larger society.
A review of wave mechanics in the pulmonary artery with an emphasis on wave intensity analysis
Authors: Su J. , Hilberg O. , Howard L. , Simonsen U. , Hughes A. D. 
Published: September 2016

AbstractMean pulmonary arterial pressure and pulmonary vascular resistance (PVR) remain the most common haemodynamic measures to evaluate the severity and prognosis of pulmonary hypertension. However, PVR only captures the non‐oscillatory component of the right ventricular hydraulic load and neglects the dynamic compliance of the pulmonary arteries and the contribution of wave transmission. Wave intensity analysis offers an alternative way to assess the pulmonary vasculature in health and disease. Wave speed is a measure of arterial stiffness, and the magnitude and timing of wave reflection provide information on the degree of impedance mismatch between the proximal and distal circulation. Studies in the pulmonary artery have demonstrated distinct differences in arterial wave propagation between individuals with and without pulmonary vascular disease. Notably, greater wave speed and greater wave reflection are observed in patients with pulmonary hypertension and in animal models exposed to hypoxia. Studying wave propagation makes a valuable contribution to the assessment of the arterial system in pulmonary hypertension, and here, we briefly review the current state of knowledge of the methods used to evaluate arterial waves in the pulmonary artery.
Desoxycorticosterone pivalate‐salt treatment leads to non‐dipping hypertension in Per1 knockout mice
Authors: Solocinski K. , Holzworth M. , Wen X. , Cheng K.‐Y. , Lynch I. J. , Cain B. D. , Wingo C. S. , Gumz M. L. 
Published: September 2016

AbstractAimIncreasing evidence demonstrates that circadian clock proteins are important regulators of physiological functions including blood pressure. An established risk factor for developing cardiovascular disease is the absence of a blood pressure dip during the inactive period. The goal of the present study was to determine the effects of a high salt diet plus mineralocorticoid on PER1‐mediated blood pressure regulation in a salt‐resistant, normotensive mouse model, C57BL/6J.MethodsBlood pressure was measured using radiotelemetry. After control diet, wild‐type (WT) and Per1 (KO) knockout mice were given a high salt diet (4% NaCl) and the long‐acting mineralocorticoid deoxycorticosterone pivalate. Blood pressure and activity rhythms were analysed to evaluate changes over time.ResultsBlood pressure in WT mice was not affected by a high salt diet plus mineralocorticoid. In contrast, Per1 KO mice exhibited significantly increased mean arterial pressure (MAP) in response to a high salt diet plus mineralocorticoid. The inactive/active phase ratio of MAP in WT mice was unchanged by high salt plus mineralocorticoid treatment. Importantly, this treatment caused Per1 KO mice to lose the expected decrease or ‘dip’ in blood pressure during the inactive compared to the active phase.ConclusionLoss of PER1 increased sensitivity to the high salt plus mineralocorticoid treatment. It also resulted in a non‐dipper phenotype in this model of salt‐sensitive hypertension and provides a unique model of non‐dipping. Together, these data support an important role for the circadian clock protein PER1 in the modulation of blood pressure in a high salt/mineralocorticoid model of hypertension.
Oral administration of Lactobacillus plantarum and Bacillus subtilis on rumen fermentation and the bacterial community in calves
Authors: Zhang Rong , Dong Xiaoli , Zhou Meng , Tu Yan , Zhang Naifeng , Deng Kaidong , Diao Qiyu 
Published: September 2016

AbstractThe objective of this study was to assess the effect of dietary probiotics on rumen fermentation and the bacterial community in dairy calves. Twelve Holstein calves were randomly allocated to three treatments: a basal diet, the basal diet supplemented with Lactobacillus plantarum GF103 (LB) or basal diet supplemented with a mixture of Lactobacillus plantarum GF103 and Bacillus subtilis B27 (LBS). A milk replacer was fed to calves from 8 days of age. A starter and alfalfa hay was offered ad libitum from 21 and 28 days of age, respectively, and the orts were weighted daily. The ruminal fluid was sampled at 56 and 83 days of age to determine the rumen fermentation characteristics. The bacterial community was analyzed by denaturing gradient gel electrophoresis (DGGE) and the number of certain bacteria was quantified by real‐time polymerase chain reaction. The ratio of total dry matter intake to average body wieght was higher in the control (P < 0.05). The DGGE fingerprint of the 16S ribosomal RNA gene was affected by the blended probiotics at 83 days of age. The number of Ruminococcus albus was lower in the LB and LBS treatment (P < 0.05). Oral administration of the probiotics affected the rumen bacterial community and the numbers of cellulolytic bacteria decreased.