bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between individualism and entrepreneurial intention – a Finnish perspective
Authors: Rantanen Teemu , Toikko Timo 
Published: March 2017

PurposeThis study aims to analyze the relationship between individualist values and entrepreneurial intentions. Previous surveys have shown that major national differences in entrepreneurial intentions can be observed within Europe and that part of this variation can be explained by cultural values, especially the individualism–collectivism dimension. However, previous findings about the relationship between individualism and entrepreneurship remain contradictory.Design/methodology/approachThis study is a micro-level analysis of the influence of individualistic values. The theoretical framework of the study is based on the theory of planned behavior (Ajzen, 1991, 2001) and theories of individualism advanced by Hofstede (1980) and Triandis and Gelfand (1998). The research data were gathered from a survey of Finnish students (N= 725).FindingsThe results show that the relationship between cultural values and entrepreneurial intention is very complex. In contrast to Hofstede (1980), the study assumes individualism and collectivism to be two separate and independent dimensions of cultural values, both of which have a positive, indirect effect on entrepreneurial intention by way of subjective norms and perceived control.Practical implicationsBoth individualist and collectivist values promote entrepreneurial intentions. From this point of view, general citizenship education, which supports the development of young people’s cultural values, can be seen as a significant element in entrepreneurship education. This suggests an instance of holistic education, the aim of which is for individuals’ autonomy and contestability to be combined with community and collective responsibility.Originality/valueThe analysis of Triandis and Gelfand (1998) has not been systematically utilized in the previous studies on entrepreneurial intentions. The findings of this study address not only the influence of psychological factors over entrepreneurial intentions but also the impact of individualist and collectivist values. The results complement the results of previous studies.
Opioid agonist treatment in the Veterans Health Administration: is health care local?
Authors: Peglow Stephanie Lee , Petrakis Ismene , Rosenheck Robert 
Published: March 2017

Purpose
Opioid use disorder (OUD) poses a national public health challenge including for the Veterans Health Administration (VHA). However, the responsiveness of VHA, as a centralized national health care system, to local conditions has not been studied. The purpose of this paper is to examine the correlation of measures of population-based OUD case identification and provision of opioid agonist treatment (OAT) in VHA and in local systems at the state level thus evaluating the responsiveness of VA as centralized health system to local conditions.

Design/methodology/approach
Correlation of VHA administrative data and local survey data reflecting OUD and OAT rates were evaluated with Pearson correlations. Further analyses examined the correlation of VHA and non-VHA OUD and OAT measures with state rates of opioid-related deaths, median income, health insurance coverage and education levels.

Findings
VHA rates of OUD and OAT at the state level were both significantly correlated with corresponding state data from the National Survey on Drug Use and Health (r=0.28, p=0.048 and r=0.71, p=0.002, respectively). Both OUD and OAT in VHA were positively and significantly correlated with state rates of opioid-related deaths, while indicators of OAT were significantly associated with higher state-level median income, health insurance coverage and levels of education.

Practical implications
Although centrally managed from Washington, D.C., VHA case identification and OAT service delivery appear to be correlated with relevant local measures.

Social implications
Significant associations with general population indicators point to underlying conditions that may shape both VHA and local health system performance.

Originality/value
Public health systems would benefit from performance evaluation data to examine responsiveness to local conditions.
BGA substrate outgassing negative impact study on Cu wire bonding
Authors: Zhang Hanmin , Hu Ming , Wang Zhijie , He Qingchun , Ye Denghong 
Published: March 2017

Purpose
The purpose of this paper is to attempt to study the failure mechanism of BGA (ball grid array) Cu wire bond ball lift and specifically focused on substrate outgassing’s impact on Cu wire bonding quality and reliability.

Design/methodology/approach
The Galvanic corrosion theory has been widely adopted in explaining the failure mechanism of Cu ball bond lift issue during reliability test or field application in the presence of moisture. In this study, ion chromatography was performed on BGA substrate halogen analysis. EDX (energy-dispersive X-ray spectroscopy) was also used to detect the contaminant’s element at the bottom surface of a window clamp. Further FTIR (Fourier transform infrared spectroscopy) analysis verified that the contamination is from substrate outgassing during wire bonding. A new window clamp design proved effective in reducing the negative impact from substrate outgassing during wire bonding.

Findings
The solder mask in a fresh substrate contains a chlorine element. The chlorine can be detected in the BGA substrate outgassing during wire bonding by FTIR and EDX analyses, which have a negative impact on the Cu wire bonding. The window clamp with a larger opening can reduce the negative impact of the Cu wire bonding from the BGA substrate outgassing.

Research limitations/implications
Because of the limitation of time and resources, bonding pad surface contamination from substrate outgassing and its correlation with Cu bonding ball lift failure after reliability test will be studied in depth later.

Originality/value
The BGA substrate outgassing has negative impacts on Cu wire bondability. A window clamp with a larger opening can reduce the negative impact from substrate outgassing.
How federalism influences welfare spending: Belgium federalism reform through the perspective of the synthetic control method
Authors: ARNOLD TOBIAS , STADELMANN‐STEFFEN ISABELLE 
Published: March 2017

AbstractThe question of whether and how federalism influences a country's welfare state has been a longstanding concern of political scientists. However, no agreement exists on exactly how, and under what conditions, federal structures impact the welfare state. This article examines this controversy. It concludes theoretically that the specific constellation of federal structures and distribution of powers need to be considered when theorising the effects of federalism on the welfare state. Using the case of Belgium and applying the synthetic control method, it is shown in the article that without the federalism reform of 1993, the country would have had further decreases in social spending rather than a consolidation of this spending in the years after 1993. In the case of Belgium, the combination of increased subnational spending autonomy in a still national financing system provided ideal conditions for a positive federalism effect on social spending to occur.
Efficacy and safety of mifepristone–buccal misoprostol for early medical abortion in an Australian clinical setting
Authors: Goldstone Philip , Walker Clara , Hawtin Katherine 
Published: March 2017

BackgroundIn 2014, a composite pack containing mifepristone‐buccal misoprostol, indicated for use to 63 days gestation replaced the existing regimen for early medical abortion (EMA) in Australia.AimsTo provide updated efficacy and safety information for the use of mifepristone–buccal misoprostol for EMA in Australia, and assess the effect of patient age and gestational age on efficacy.Materials and methodsObservational cohort study of 15 008 women attending one of 16 Marie Stopes International clinics in Australia for an EMA (gestational age ≤ 63 days) between 1 March 2013 and 30 September 2015. Administration of 200 mg oral mifepristone in‐clinic was followed 24–48 h later by 800 μg buccal misoprostol self‐administered at home. Method success was defined as complete abortion not requiring surgical intervention.ResultsFollow‐up information was available for 87.14% (13 078/15 008) of women. Likelihood of follow‐up was significantly lower for women from rural or remote locations (adjusted odds ratio, 0.47; P < 0.001). Medical abortion was successful in 95.16% (12 445/13 078) of women with follow‐up. Higher patient and gestational ages were associated (P < 0.001) with a slight increase in method failure. There were 674 serious adverse events (5.15%), mainly due to method failure. Infection (15; 0.11%) and haemorrhage (17; 0.13%) were rare. One death was recorded (<0.01%); however, an association between EMA and cause of death, necrotising pneumonia, was not established.ConclusionMifepristone–buccal misoprostol is an effective and safe alternative to surgical termination of pregnancy up to 63 days gestation.
Carbon and Biodiversity Impacts of Intensive Versus Extensive Tropical Forestry
Authors: Griscom Bronson W. , Goodman Rosa C. , Burivalova Zuzana , Putz Francis E. 
Published: March 2017

AbstractHow should we meet the demand for wood while minimizing climate and biodiversity impacts? We address this question for tropical forest landscapes designated for timber production. We model carbon and biodiversity outcomes for four archetypal timber production systems that all deliver the same volume of timber but vary in their spatial extent and harvest intensity. We include impacts of variable deforestation risk (secure land tenure or not) and alternative harvesting practices (certified reduced‐impact logging methods or not).We find that low‐intensity selective logging offers both the best and the worst overall outcomes per unit wood produced, depending on whether certified reduced‐impact logging methods are used and whether land tenure is secure. Medium‐to‐high‐intensity natural forest harvests and conversion to high‐yield plantations generate intermediate outcomes. Deforestation risk had the strongest influence on overall outcomes. In the absence of deforestation, logging impacts were lowest at intermediate and high management intensities.
Habitat variation, mutualism and predation shape the spatio‐temporal dynamics of tansy aphids
Authors: SENFT MATTHIAS , WEISSER WOLFGANG W. , ZYTYNSKA SHARON E. 
Published: March 2017

1. Spatially distributed resources can lead to the formation of metapopulations, where individual subpopulations are often small and can experience frequent local extinction events followed by recolonisation. An example of terrestrial metapopulations are specialised phytophagous insects on their patchily distributed host plants.2. The present study investigated the population dynamics of a specialised aphid (Metopeurum fuscoviride) on its patchily distributed host plant (Tanacetum vulgare) and associated community of mutualistic ants and predators in a small‐scale field site. Furthermore, aphid habitat differences (plant size, C/N ratio, location and surrounding vegetation) were quantified, and seasonal timing and precipitation were considered.3. Seasonal timing and precipitation both had effects on aphid colonisation, extinction events and aphid colony persistence. Towards the end of the season, and after higher precipitation, aphid colonisation events decreased and extinction events increased. Plant size and location as well as aphid within‐field dispersal determined the spatio‐temporal distribution of aphid colonies.4. Mutualistic ants (Lasius niger and Myrmica rubra) increased the chance of establishment of aphid colonies. However, when M. rubra was tending, aphid colony persistence was reduced. Aphid persistence and extinction were dependent on aphid abundance, as a higher colony size reduced the probability of extinction by predation.5. The results emphasise the importance of dispersal limitation, population growth and the presence of mutualists when studying the spatio‐temporal dynamics of tansy aphids, particularly in a small‐scale field site.
Biomechanical markers and theoretical concepts related to haemophilic ankle and subtalar joint arthropathy: introducing the term ‘haemophilic tarsal pan‐arthropathy’
Authors: Lobet S. , McCarthy A. , Hermans C. , Peerlinck K. , Matricali G. A. , Staes F. , Deschamps K. 
Published: March 2017

BackgroundAlthough regular factor replacement can reduce the incidence of joint bleeds and slow down the development of haemophilic arthropathy, the ankle joint remains particularly vulnerable even in children with haemophilia on primary or secondary prophylaxis and is now the primary joint affected. The heterogeneity in the pathoaetiology of haemophilic ankle arthropathy means that the functional consequences of early stage of ankle arthropathy are difficult to define as early morphological and structural changes can be observed in clinically asymptomatic ankles. In this context, understanding biomechanics of the normal and arthritic foot is complex and difficult to quantify unless considering the foot as multiple functional segments using more sophisticated assessment tools such as multisegment foot models. However, this understanding can undoubtedly aid in the analysis of an underlying clinical problem and provide a strategic basis for a more optimal management.AimsThe purpose of this narrative review was firstly to revise information on the anatomy and biomechanics of the foot and ankle. Finally, related biomechanical markers of human motor performance, which are potentially implicated in the development of haemophilic ankle arthropathy, will be discussed based on published literature and expert opinion.Materials and methodsSearches in published literature were limited to the year 2000 onwards.ResultsAlthough the ankle (tibiotalar joint) is the most commonly affected joint, associated subtalar joint (SJT) involvement is often seen. This would therefore imply that an alternative phraseology might be better.Discussion and conclusionIn this context, the authors propose the use of ‘haemophilic tarsal pan‐arthropathy’ (HTPA) which encompasses both tibiotalar and subtalar joints.
Beliefs about medicines among Hong Kong hospital outpatients†
Authors: Wan Bosco K F , Cheung Walter H K , Ball Patrick A , Jackson David M , Maynard Gregg J 
Published: March 2017

Abstract

Objectives
(1) To identify demographic characteristics associated with different patients' belief attitudes among older Hong Kong hospital outpatients. (2) To identify important implementation criteria for developing a more effective adherence-improving intervention.

Methods
Six hundred and ninety-eight patients completed a questionnaire consisting of demographic information and Belief about Medicines Questionnaire. Findings were statistically analysed.

Key findings
Among respondents, 56.9% were either in the hesitant (Mixed-feelings and Indifferent) or negative (Distrustful) medication belief constructs. The majority of these patients were younger females, with better education, taking fewer regular medications and for shorter duration. Rheumatoid and gout accounted for 46.1% of cases in the Distrustful construct, while cardiovascular and diabetic conditions accounted for 63.8% of cases in the positive (In-favour) construct. Patients' concerns about medications were reaffirmed to be a predominant factor affecting medication beliefs. The mean Necessity–Concern Differential scores in the two hesitant constructs illustrated that patients within these two constructs were more pliant towards medicines and, therefore, were predicted to be more subject to modification.

Conclusions
Our results identified the demographic characteristics of patients with negative or hesitant belief attitudes about medicines. In order to effectively achieve improvement in long-term beliefs about medications, the design of interventions should target positively modifying belief attitudes in these two patient groups. Furthermore, addressing patients' concern about their medicines was reaffirmed to be an important criterion for researchers to focus on when designing effective interventions in the future.
Incidence and risks for surgical site infection after adult tibial plateau fractures treated by ORIF: a prospective multicentre study
Authors: Zhu Yanbin , Liu Song , Zhang Xiaolin , Chen Wei , Zhang Yingze 
Published: March 2017

AbstractTibial plateau fractures are difficult to treat and more likely complicated by subsequent surgical site infection (SSI). There is limited information about its characteristics and related risk factors for SSI. This study was designed as a prospective and multicentre one to address this issue. From July to 15 November in 2014, 235 patients with tibial plateau fractures were treated by open reduction and internal fixation (ORIF) and followed up with complete data. Twelve patients (5·1%, 12/235) developed SSI, with 2·1% for deep SSI and 3·0% for superficial SSI. Most of them (10/12) occurred during the hospital stays. The median occurrence time was 6 days after operation (range, 2–26 days). We use univariate and multivariate logistic regression models to investigate the potential risk factors. In the univariate analysis, open fracture, prolonged preoperative stay, smoking habitus and preoperative abnormal neutrophil (NEUT) count were significant risk factors for SSI occurrence. However, in multivariate analysis, only open fracture (OR, 3·31; 95%, 1·06–1·84) and current smoking status (OR, 5·68; 95% CI, 1·56–20·66) remained significant. We recommend that smoking cessation programme is introduced at the time of admission to the hospital and elaborative evaluation of fracture severity and soft‐tissue damage is performed with an aim of reducing the risk of post‐operative SSI.
Acquired Hemolytic Anemia Associated with IgA Anti‐e
Authors: Stratton F. , Rawlinson V. I. , Chapman S. A. , Pengelly C. D. R. , Jennings R. C. 
Published: March 2017

Acquired hemolytic anemia in a Caucasian female patient with direct antiglobulin test positive only with anti‐IgA is described. The patient's serum contained 7S IgA anti‐e antibody. The significance of this, from the point of view of broad spectrum antiglobulin sera, is discussed.The patient's serum contained 7S IgA anti‐e antibody. The significance of this, from the point of view of broad spectrum antiglobulin sera, is discussed.
Long‐term results of periodontal regenerative therapy: A retrospective practice‐based cohort study
Authors: Bröseler Frank , Tietmann Christina , Hinz Ann‐Katrin , Jepsen Søren 
Published: March 2017

AbstractAimEvaluation of the long‐term effectiveness of regenerative treatment of intra‐bony defects in periodontal practice.Material and MethodsA total of 1,008 intra‐bony defects in 176 patients were analysed after using collagen‐added deproteinized bovine bone mineral (DBBMc) with or without collagen membrane (CM) or enamel matrix derivative (EMD). Defects were classified as one‐ and two‐wall and as shallow (≤6 mm), moderate (>6 and <11 mm) and deep (≥11 mm). Radiographic bone level changes were evaluated after 1 year, 2 to 4 years and 5 to 10 years.ResultsMean radiographic defect fill was 3.8 mm after 1 year and remained stable up to 10 years. Deep and moderate defects showed a higher degree of fill than shallow defects (53.3%, 49.2%, 42.9%). Tooth loss amounted to 2.6%, was dependent on initial defect size (1.2% shallow, 1.4% moderate, 5.7% deep defects) and occurred mainly due to endodontic reasons.ConclusionsWithin the limits of the retrospective study design, the findings indicate that periodontal treatment using DBBMc with or without CM or EMD can lead to long‐term defect reduction and tooth survival for up to 10 years in the setting of a periodontal practice.
Mutant eIF2B leads to impaired mitochondrial oxidative phosphorylation in vanishing white matter disease
Authors: Raini Gali , Sharet Reut , Herrero Melisa , Atzmon Andrea , Shenoy Anjana , Geiger Tamar , Elroy‐Stein Orna 
Published: March 2017

AbstractEukaryotic translation initiation factor 2B (eIF2B) is a master regulator of protein synthesis under normal and stress conditions. Mutations in any of the five genes encoding its subunits lead to vanishing white matter (VWM) disease, a recessive genetic deadly illness caused by progressive loss of white matter in the brain. In this study we used fibroblasts, which are not involved in the disease, to demonstrate the involvement of eIF2B in mitochondrial function and abundance. Mass spectrometry of total proteome of mouse embryonic fibroblasts (MEFs) isolated from Eif2b5R132H/R132H mice revealed unbalanced stoichiometry of proteins involved in oxidative phosphorylation and of mitochondrial translation machinery components, among others. Mutant MEFs exhibit 55% decrease in oxygen consumption rate per mtDNA content and 47% increase in mitochondrial abundance (p < 0.005), reflecting adaptation to energy requirements. A more robust eIF2B‐associated oxidative respiration deficiency was found in mutant primary astrocytes, which exhibit > 3‐fold lower ATP‐linked respiration per cell despite a 2‐fold increase in mtDNA content (p < 0.03). The 2‐fold increase in basal and stimulated glycolysis in mutant astrocytes (p ≤ 0.03), but not in MEFs, demonstrates their higher energetic needs and further explicates their involvement in the disease. The data demonstrate the critical role of eIF2B in tight coordination of expression from nuclear and mitochondrial genomes and illuminates the importance of mitochondrial function in VWM pathology. Further dissection of the signaling network associated with eIF2B function will help generating therapeutic strategies for VWM disease and possibly other neurodegenerative disorders.
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Assessment of antioxidative and selenium status by seleno‐dependent glutathione peroxidase activity in different blood fractions using a pig model: issues for clinical nutrition and research
Authors: Dalto D. B. , Lapointe J. , Matte J.‐J. 
Published: March 2017

SummaryBlood seleno‐dependent glutathione peroxidase (SeGPX) activity is widely used as a metabolic indicator of systemic antioxidative status despite inconsistent responses in the literature. This study aimed to compare SeGPX activity profiles in different blood fractions, expressed with different reference units, and assess their impact on interpretation of results. Two studies on selenium (Se) metabolism in gilts, including long‐term and peri‐oestrus SeGPX activity profiles, were submitted to analysis of variance with double repeated measures, after data set standardization. Differences between studies were experimental period (three post‐pubertal oestrus or five post‐pubertal oestrus +30 days of gestation) and sample type (whole blood or blood plasma). No difference was observed between whole‐blood long‐term profiles (three oestrus) for SeGPX activity/mg haemoglobin (SeGPXhb) vs. SeGPX activity/ml whole blood (SeGPXwb; p = 0.29). No long‐term difference was observed in whole blood between profiles according to dietary Se provision (basal and dietary Se‐supplemented groups; p ≥ 0.12). Blood plasma long‐term profiles (five oestrus + 30 days gestation) for SeGPX/mg blood plasma protein (SeGPXpro) were different from SeGPX/ml blood plasma (SeGPXpla) according or not to Se provision (p ≤ 0.007 and p < 0.001 respectively). However, regardless of Se provision (p ≥ 0.80), when excluding gestation from the model, blood plasma profiles were similar. During the peri‐oestrus period (day −4 to +3), regardless of Se provision, SeGPX activity profiles differed according to reference units in both studies (p < 0.001). However, considering Se provision, similar profiles were observed in whole blood and blood plasma (p ≥ 0.27) for basal Se groups, whereas in Se‐supplemented groups they differed for both sample types (p ≤ 0.02). In conclusion, reference units influence interpretation of SeGPX activity according to physiological state. During oxidative stress periods, this effect depends upon dietary Se provision.