bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of rice koji inoculated with Aspergillus luchuensis on the biochemical and sensory properties of a sailfin sandfish (Arctoscopus japonicus) fish sauce
Authors: Kim Byoung‐Mok , Park Jae‐Ho , Kim Dong‐Soo , Kim Young‐Myung , Jun Joon‐Young , Jeong In‐Hak , Nam Si‐Youl , Chi Young‐Min 
Published: June 2016

SummaryThe effects of rice koji inoculated with Aspergillus luchuensis on the biochemical and sensory properties of fish sauce produced from sailfin sandfish (Arctoscopus japonicus) with different salt concentrations (10% and 20%) were investigated over 10 months. Fish sauces prepared from sailfin sandfish with rice koji and a low salt concentration had higher total nitrogen, amino nitrogen and total free amino acid than did those without rice koji or with a high salt concentration. Sensory evaluation of fish sauces prepared with rice koji and a low salt concentration found better taste, flavour and overall acceptance than those prepared without rice koji during fermentation (P < 0.05). The use of rice koji increased the total nitrogen, amino nitrogen and free amino acid and also enhanced the sensory qualities during fermentation. These results suggest that the use of rice koji can result in a low‐salt fish sauce with better flavour.
Vortex‐dislodged cells from bone marrow trephine biopsy yield satisfactory results for flow cytometric immunophenotyping
Authors: Bommannan K. , Sachdeva M. U. S. , Gupta M. , Bose P. , Kumar N. , Sharma P. , Naseem S. , Ahluwalia J. , Das R. , Varma N. 
Published: June 2016

SummaryIntroductionA good bone marrow (BM) sample is essential in evaluating many hematologic disorders. An unsuccessful BM aspiration (BMA) procedure precludes a successful flow cytometric immunophenotyping (FCI) in most hematologic malignancies. Apart from FCI, most ancillary diagnostic techniques in hematology are less informative. We describe the feasibility of FCI in vortex‐dislodged cell preparation obtained from unfixed trephine biopsy (TB) specimens.MethodsIn pancytopenic patients and dry tap cases, routine diagnostic BMA and TB samples were complemented by additional trephine biopsies. These supplementary cores were immediately transferred into sterile tubes filled with phosphate‐buffered saline, vortexed, and centrifuged. The cell pellet obtained was used for flow cytometric immunophenotyping.ResultsOf 7955 BMAs performed in 42 months, 34 dry tap cases were eligible for the study. Vortexing rendered a cell pellet in 94% of the cases (32 of 34), and FCI rendered a rapid diagnosis in 100% of the cases (32 of 32) where cell pellets were available.ConclusionWe describe an efficient procedure which could be effectively utilized in resource‐limited centers and reduce the frequency of repeat BMA procedures.
Innate lymphoid cell regulation of adaptive immunity
Authors: Withers David R. 
Published: June 2016

SummaryInnate lymphoid cells (ILCs) were identified principally as non‐T‐cell sources of key cytokines, able to provide rapid and early production of these molecules in the support of tissue homeostasis, repair and response to infection. As our understanding of these cells has developed, it has become evident that ILCs can impact on lymphocytes through a range of mechanisms. Hence, an exciting area of research has evolved in determining the extent to which ILCs may regulate adaptive immune responses. This review will focus initially on our current understanding of where ILC populations are located and what this means for potential cellular interactions. Mechanisms underpinning such interactions and how they may contribute to controlling adaptive immunity will then be considered.
A Comparison of two Robust Estimation Methods for Business Surveys
Authors: Graham Clark Robert , Kokic Philip , A. Smith Paul 
Published: June 2016

SummaryTwo alternative robust estimation methods often employed by National Statistical Institutes in business surveys are two‐sided M‐estimation and one‐sided Winsorisation, which can be regarded as an approximate implementation of one‐sided M‐estimation. We review these methods and evaluate their performance in a simulation of a repeated rotating business survey based on data from the Retail Sales Inquiry conducted by the UK Office for National Statistics. One‐sided and two‐sided M‐estimation are found to have very similar performance, with a slight edge for the former for positive variables. Both methods considerably improve both level and movement estimators. Approaches for setting tuning parameters are evaluated for both methods, and this is a more important issue than the difference between the two approaches. M‐estimation works best when tuning parameters are estimated using historical data but is serviceable even when only live data is available. Confidence interval coverage is much improved by the use of a bootstrap percentile confidence interval.
PARIS' HAIR AND THE STRUCTURE OF HORACE, CARMEN 1.15
Authors: BERNSDORFF HANS 
Published: June 2016

Abstract
The aim of this paper is to take into consideration the position of Carm. 1.15.19–20 within the structure of the whole ode (at a ‘false closure’). By this means, a fresh argument in favour of the variant crinis will be supplied, since the motif of hair is a closural device.
DINING AS SPECTACLE IN LATE ROMAN HOUSES
Authors: STEPHENSON JOHN 
Published: June 2016

AbstractThe elements of visual culture preserved in late Roman houses confirm an intense interest in dramatic visual display. This study employs an interpretive lens of spectacle to examine a new form of banquet space amd furnishings in the period, as well as a new style of ‘dinner-theatre’ they served. By considering ancient art as inseparable from active contexts and ephemeral events, a more sophisticated understanding of a society's self-definition through art emerges. Rather than being epiphenomenal to the poliltical culture of late antiquity, spectacle is argued to be central to the creation and contestation of power structures: performance is politics.
ZELA, ACCLAMATIONS, CARACALLA – AND PARTHIA?
Authors: BURNETT ANDREW 
Published: June 2016

Abstract
A coin which has lain unrecognized in the BM, which can be identified as an unpublished coin of Zela, proclaims that if ‘the emperors are victorious the world is happy’. The formula is analysed in the context of imperial acclamations and their language, which differs from that normally found on coinage. It is suggested that the coin may have been struck in connection with an otherwise unknown visit by Caracalla to the East in AD 207, for which other evidence is assembled. A catalogue of acclamations on Roman coins, medallions, and tokens is provided.
Recent Developments in the Acte Clair Case Law of the EU Court of Justice: Towards a more Flexible Approach
Authors: Limante Agne 
Published: June 2016

AbstractThis article examines the acte clair doctrine in light of the recent rulings of the Court of Justice of the European Union in Ferreira da Silva and X and van Dijk. It first analyses the earlier case law on acte clair, disclosing inconsistencies in the application of its requirements. Then, it offers a critical review of Ferreira da Silva and X and van Dijk. It claims that the Cilfit criteria, although often quoted in judgments and doctrine, have been applied neither consistently nor truly rigidly by the Court. Instead, a more flexible approach to acte clair requirements is taking shape, while the Court is simultaneously reminding national courts that its discretion on preliminary reference issues is not unlimited. Finally, the article criticizes Ferreira da Silva and X and van Dijk for missing the opportunity to further clarify the normative content and the legal status of the Cilfit criteria.
Localization of a Trypanosome Peroxin to the Endoplasmic Reticulum
Authors: Bauer Sarah T. , McQueeney Kelley E. , Patel Terral , Morris Meredith T. 
Published: June 2016

AbstractTrypanosoma brucei is the causative agent of diseases that affect 30,000–50,000 people annually. Trypanosoma brucei harbors unique organelles named glycosomes that are essential to parasite survival, which requires growth under fluctuating environmental conditions. The mechanisms that govern the biogenesis of these organelles are poorly understood. Glycosomes are evolutionarily related to peroxisomes, which can proliferate de novo from the endoplasmic reticulum or through the growth and division of existing organelles depending on the organism and environmental conditions. The effect of environment on glycosome biogenesis is unknown. Here, we demonstrate that the glycosome membrane protein, TbPex13.1, is localized to glycosomes when cells are cultured under high glucose conditions and to the endoplasmic reticulum in low glucose conditions. This localization in low glucose was dependent on the presence of a C‐terminal tripeptide sequence. Our findings suggest that glycosome biogenesis is influenced by extracellular glucose levels and adds to the growing body of evidence that de novo glycosome biogenesis occurs in trypanosomes. Because the movement of peroxisomal membrane proteins is a hallmark of ER‐dependent peroxisome biogenesis, TbPex13.1 may be a useful marker for the study such processes in trypanosomes.
Saddleback syndrome in European sea bass Dicentrarchus labrax (Linnaeus, 1758): anatomy, ontogeny and correlation with lateral‐line, anal and pelvic fin abnormalities
Authors: Fragkoulis S , Paliogiannis H , Kokkinias P , Chiers K , Adriaens D , Koumoundouros G 
Published: June 2016

AbstractThis study focused on the anatomy and ontogeny of saddleback syndrome (SBS) in reared European sea bass. The abnormality was detected at an unusually high frequency (12–94%) during a routine quality control in a commercial hatchery. Anatomically the abnormality was mainly characterized by the loss of 1–5 hard spines and severe abnormalities of the proximal pterygiophores (anterior dorsal fin), size reduction of a few lepidotrichia, missing lepidotrichia and/or lepidotrichia of poor ossification (posterior dorsal fin). SBS was significantly correlated with abnormalities of the anal and pelvic fins in all the examined populations. Moreover, in juvenile fish, SBS was significantly correlated with an abnormal lack of sectors of the lateral line. The examination of early larval samples revealed that SBS was ontogenetically associated with severe abnormalities of the primordial marginal finfold, which developed at the flexion stage (ca 8.5–11.0 mm SL). Histologically, these abnormalities were associated with extensive epidermal erosion. The results are discussed in respect of the critical ontogenetic period and the possible causative factors of SBS in European sea bass. It is suggested that causative factors acted during a wide ontogenetic period including flexion and metamorphosis phases.
Combined antiparasitic and anti‐inflammatory effects of the natural polyphenol curcumin on turbot scuticociliatosis
Authors: Mallo N , DeFelipe A P , Folgueira I , Sueiro R A , Lamas J , Leiro J M 
Published: June 2016

AbstractThe histiophagous scuticociliate Philasterides dicentrarchi is the aetiological agent of scuticociliatosis, a parasitic disease of farmed turbot. Curcumin, a polyphenol from Curcuma longa (turmeric), is known to have antioxidant and anti‐inflammatory properties. We investigated the in vitro effects of curcumin on the growth of P. dicentrarchi and on the production of pro‐inflammatory cytokines in turbot leucocytes activated by parasite cysteine proteases. At 100 μm, curcumin had a cytotoxic effect and completely inhibited the growth of the parasite. At 50 μm, curcumin inhibited the protease activity of the parasite and expression of genes encoding two virulence‐associated proteases: leishmanolysin‐like peptidase and cathepsin L‐like. At concentrations between 25 and 50 μm, curcumin inhibited the expression of S‐adenosyl‐L‐homocysteine hydrolase, an enzyme involved in the biosynthesis of the amino acids methionine and cysteine. At 100 μm, curcumin inhibited the expression of the cytokines tumour necrosis factor‐alpha (TNF‐α) and interleukin‐1 beta (IL‐1β) produced in turbot leucocytes activated by parasite proteases. Results show that curcumin has a dual effect on scuticociliatosis: an antiparasitic effect on the catabolism and anabolism of ciliate proteins, and an anti‐inflammatory effect that inhibits the production of proinflammatory cytokines in the host. The present findings suggest the potential usefulness of this polyphenol in treating scuticociliatosis.
Susceptibility of a number of Australian freshwater fishes to dwarf gourami iridovirus (Infectious spleen and kidney necrosis virus)
Authors: Rimmer A E , Whittington R J , Tweedie A , Becker J A 
Published: June 2016

AbstractMegalocytiviruses cause high mortality diseases that have seriously impacted aquaculture, with the most frequent outbreaks occurring in East and South‐East Asia. The international trade of juvenile fish for food and ornamental aquaculture has aided the spread of these viruses, which have spread to Europe and Australia and other regions. Australian freshwater fishes were examined for susceptibility to infection with the exotic megalocytivirus, dwarf gourami iridovirus (DGIV), which belongs to a group with the type species, Infectious spleen and kidney necrosis virus (ISKNV). Fish were held at 23 ± 1 °C and challenged by intraperitoneal (IP) injection or by cohabitation with Murray cod, Maccullochella peelii (Mitchell) infected with DGIV. A species was deemed to be susceptible to DGIV based on evidence of viral replication, as determined by qPCR, and megalocytic inclusion bodies observed histologically. Horizontal transmission occurred between infected Murray cod and golden perch, Macquaria ambigua (Richardson), Macquarie perch, Macquaria australasica (Cuvier) and Murray cod. This indicated that DGIV shed from infected fish held at 23 °C can survive in fresh water and subsequently infect these naïve fish. Further, DGIV administered IP was highly pathogenic to golden perch, Macquarie perch and Murray cod. Compared to these species, the susceptibility of southern pygmy perch, Nannoperca australis (Gunther) was lower. Freshwater catfish (dewfish), Tandanus tandanus (Mitchell), were not susceptible under the experimental conditions based on the absence of clinical disease, mortality and virus replication. This study showed the potential risks associated with naïve and DGIV‐infected fish sharing a common water source.
Ultrasound‐Assisted Extraction of Apricot Kernel Oil: Effects on Functional and Rheological Properties
Authors: Gayas Bazilla , Kaur Gagandeep , Gul Khalid 
Published: June 2016

AbstractAn ultrasound‐assisted procedure was applied to the extraction of oil from apricot kernels. The best possible combination of extraction parameters was obtained with the response surface methodology at a three‐variable, three level experiments Box‐Behnken design. The optimum extraction parameters were as follows: extraction time: 43.95 min; extraction temperature: 51.72 °C; and solvent/sample ratio: 19.8:01 at a fixed ultrasonic frequency of 40 kHz. Close agreement between experimental and predicted values were found. The viscosity values decreased with increase in the shear rate. Viscosities of samples treated with ultrasound for longer time were relatively higher due to dissolution of heavy suspended components. The results suggest that ultrasonic‐assisted extraction could be a good option for the extraction of oil from apricot kernels.Practical ApplicationsUltrasound treatment is a nonthermal and novel processing technology for extraction of biologically active food components. UAE in this study had a pronounced effect on the overall qualities of the extracted oil while maintaining the quality. Rheological properties of UAE extracted any edible oil is reported first time. This study can be beneficial for industries and researchers for enhancing the yield and maintaining the quality of the oils.
Annual Report of the Committee on Gynecologic Oncology, Japan Society of Obstetrics and Gynecology: Patient Annual Report for 2013 and Treatment Annual Report for 2008
Authors: Saito Toshiaki , Katabuchi Hidetaka 
Published: June 2016

AbstractThe Japan Society of Obstetrics and Gynecology collects and analyzes annual data on gynecologic cancers from member institutions. We present the Patient Annual Report for 2013 and the Treatment Annual Report for 2008. Data on 7280 patients with cervical cancer, 8952 with endometrial cancer, 5792 with ovarian cancer and 1903 with ovarian borderline tumor for whom treatment was initiated in 2013 were summarized in the Patient Annual Report. Stage I accounted for 56.7%, stage II for 23.4%, stage III for 9.8% and stage IV for 10.2% of all patients with cervical cancer. Stage I accounted for 71.7%, stage II for 6.5%, stage III for 14.5% and stage IV for 7.3% of all patients with endometrial cancer. Stage I accounted for 42.2%, stage II for 9.8%, stage III for 28.2% and stage IV for 8.3% of all patients with ovarian cancer. Data on the prognosis of 3658 patients with cervical cancer, 4159 with endometrial cancer and 2866 with ovarian cancer for whom treatment was initiated in 2008 were analyzed in the Treatment Annual Report. Survival was analyzed by using the Kaplan–Meier method, the log–rank test and the Wilcoxon test. The 5‐year overall survival rates for patients with cervical cancer were 93.0% for stage I, 73.1% for stage II, 55.2% for stage III and 24.2% for stage IV. The equivalent rates for patients with endometrial cancer were 94.5%, 90.3%, 74.2% and 24.0%, respectively; and those for patients with ovarian cancer (surface epithelial–stromal tumors) were 90.5%, 73.5%, 48.1% and 29.4%, respectively.
Association between vascular endothelial growth factor expression and lymph node metastasis in cervical cancer: A meta‐analysis
Authors: Sun Haiying , Tang Fangxu , Zhou Shasha , Li Xiong , Wang Shaoshuai , Huang Kecheng , Jia Yao , Tian Xun , Ma Ding , Li Shuang 
Published: June 2016

AbstractAimThe expression of vascular endothelial growth factor (VEGF) by cancer cells has been identified as a factor that is associated with lymph node metastasis (LNM) in some cancers, but an accurate description of the relation between VEGF and LNM in cervical cancer is lacking. We conducted a concurrent meta‐analysis to investigate this issue.MethodsWe searched PubMed and EMBASE for articles addressing the association between VEGF and cervical cancer. We used stata 12.0 and calculated the crude odds ratios (OR) and corresponding 95% confidence intervals (CI). Heterogeneity between the studies included was assessed by Cochran's Q‐test.ResultsOverall, 16 relevant studies with 426 cases and 751 controls were included in our study. The results demonstrated that cervical cancer patients with VEGF‐positive expression had a 2.87‐fold higher risk of LNM than patients without VEGF‐positive expression (95%CI = 1.85–4.44, P < 0.001). Furthermore, subgroup analysis by ethnicity revealed that VEGF‐positive expression could increase the risk of LNM in cervical cancer among Asian populations (OR = 2.55, 95%CI = 1.61–4.03, P < 0.001) and Caucasian populations (OR = 8.81, 95%CI = 2.78–27.88, P < 0.001). Moreover, subgroup analysis by country revealed that VEGF‐positive expression could increase the risk of LNM in cervical cancer among Chinese populations (OR = 3.38, 95%CI = 2.18–5.25, P < 0.001) but not among Korean populations (P = 0.84) or Japanese populations (P = 0.06). Subgroup analysis based on sample size proved that VEGF‐positive expression was statistically associated with LNM in a large sample group.ConclusionOur study revealed that VEGF‐positive expression is related with higher risk of LNM in cervical cancer.
Pre‐school screening for developmental and emotional health: Comparison with neurodevelopmental assessment
Authors: Burakevych Nataliia , McKinlay Christopher Joel Dorman , Alsweiler Jane Marie , Wouldes Trecia Ann , Harding Jane Elizabeth 
Published: June 2016

AimThe study aim was to compare detection of and referral for developmental and emotional problems in a school readiness screening programme (New Zealand Before School Check, B4SC) with that of a comprehensive neurodevelopmental assessment.MethodsThis is a prospective cohort study of children (n = 274) born at risk of neonatal hypoglycaemia and recruited to a follow‐up study of neurodevelopmental outcomes at 4.5 years (Children with Hypoglycaemia and their Later Development (CHYLD) Study). Children identified as of significant concern for developmental and emotional problems, and referrals made, were compared in the B4SC and CHYLD Study. Scores of the parent‐completed Strengths and Difficulties Questionnaire used in both assessments were compared.ResultsOf the 274 children who underwent clinical neurodevelopmental assessment at a mean (standard deviation) age of 53.3 (1.8) months, 237 had the B4SC developmental and emotional health screening. Of these, 44 (19%) children met B4SC referral criteria, and 15 (6%) were referred, but only 21 (9%) children met CHYLD referral criteria, and 10 (4%) were referred. Twelve children (5%) met both the B4SC and CHYLD referral criteria, and two were referred by both. When assessed twice, 39 (17%) children changed parent‐completed Strengths and Difficulties Questionnaire category. Children who did not have B4SC screening had higher mean total difficulties score (10.5 vs. 8.2, P = 0.009) and were more likely to have cognitive delay than those who were screened (19% vs. 8%, P = 0.04).ConclusionMore children met referral criteria for the B4SC screening programme than for a more comprehensive neurodevelopmental assessment. Children who did not have screening had a higher incidence of cognitive and behaviour problems than those who did.
A comprehensive generic‐level phylogeny of the sunflower family: Implications for the systematics of Chinese Asteraceae
Authors: Fu Zhi‐Xi , Jiao Bo‐Han , Nie Bao , Zhang Guo‐Jin , Gao Tian‐Gang ,   China Phylogeny Consortium
Published: June 2016

AbstractThe sunflower family (Asteraceae) is the largest and the most diverse flowering plant family, comprising 24 000–30 000 species and 1600–1700 genera. In China, Asteraceae are also the largest family, with approximately 2336 indigenous species in 248 genera. In the past two decades, molecular phylogenetic analyses has contributed greatly to our understanding of the systematics of Asteraceae. Nevertheless, the large‐scale analyses and knowledge about the relationships of Chinese Asteraceae at the generic level as a whole are far from complete due to difficulties in sampling. In this study, we presented a three‐marker (rbcL, ndhF, and matK) phylogeny of Asteraceae, including 506 genera (i.e., approximately one‐third of Asteraceae genera). The study sampled 200 Chinese genera (i.e., approximately 80% of Chinese Asteraceae genera). The backbones of the new phylogeny were largely congruent with earlier studies, with 13 subfamilies and 45 tribes recognized. Chinese Asteraceae were distributed in 7 subfamilies (Mutisioideae, Wunderlichioideae, Carduoideae, Pertyoideae, Gymnarrhenoideae, Cichorioideae, and Asteroideae) and 22 tribes (Mutiseae, Hyalideae, Cardueae, Pertyeae, Gymnarrheneae, Vernonieae, Cichorieae, Doroniceae, Senecioneae, Astereae, Anthemideae, Gnaphalieae, Calenduleae, Inuleae, Athroismeae, Helenieae, Coreopsideae, Neurolaeneae, Tageteae, Millieae, Eupatorieae, and Heliantheae). Chinese Asteraceae lacked 6 basal subfamilies and 23 tribes. Several previously ambiguous relationships were clarified. Our analyses also resolved some unplaced genera within Chinese Asteraceae. Finally, our phylogenetic tree was used to revise the classification for all genera of Chinese Asteraceae. In total, 255 genera, 22 tribes, and 7 subfamilies in China are recognized.