bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building branched tissue structures: from single cell guidance to coordinated construction
Authors: Spurlin James W. , Nelson Celeste M. 
Published: March 2017

Branched networks are ubiquitous throughout nature, particularly found in tissues that require large surface area within a restricted volume. Many tissues with a branched architecture, such as the vasculature, kidney, mammary gland, lung and nervous system, function to exchange fluids, gases and information throughout the body of an organism. The generation of branched tissues requires regulation of branch site specification, initiation and elongation. Branching events often require the coordination of many cells to build a tissue network for material exchange. Recent evidence has emerged suggesting that cell cooperativity scales with the number of cells actively contributing to branching events. Here, we compare mechanisms that regulate branching, focusing on how cell cohorts behave in a coordinated manner to build branched tissues.This article is part of the themed issue ‘Systems morphodynamics: understanding the development of tissue hardware’.
Inferring cellular forces from image stacks
Authors: Veldhuis Jim H. , Ehsandar Ahmad , Maître Jean-Léon , Hiiragi Takashi , Cox Simon , Brodland G. Wayne 
Published: March 2017

Although the importance of cellular forces to a wide range of embryogenesis and disease processes is widely recognized, measuring these forces is challenging, especially in three dimensions. Here, we introduce CellFIT-3D, a force inference technique that allows tension maps for three-dimensional cellular systems to be estimated from image stacks. Like its predecessors, video force microscopy and CellFIT, this cell mechanics technique assumes boundary-specific interfacial tensions to be the primary drivers, and it constructs force-balance equations based on triple junction (TJ) dihedral angles. The technique involves image processing, segmenting of cells, grouping of cell outlines, calculation of dihedral planes, averaging along three-dimensional TJs, and matrix equation assembly and solution. The equations tend to be strongly overdetermined, allowing indistinct TJs to be ignored and solution error estimates to be determined. Application to clean and noisy synthetic data generated using Surface Evolver gave tension errors of 1.6–7%, and analyses of eight-cell murine embryos gave estimated errors smaller than the 10% uncertainty of companion aspiration experiments. Other possible areas of application include morphogenesis, cancer metastasis and tissue engineering.This article is part of the themed issue ‘Systems morphodynamics: understanding the development of tissue hardware’.
Striatal action-value neurons reconsidered
Authors: Elber-Dorozko Lotem , Loewenstein Yonatan 
Published: March 2017

AbstractIt is generally believed that during economic decisions, striatal neurons represent the values associated with different actions. This hypothesis is based on a large number of studies, in which the neural activity of striatal neurons was measured while the subject was learning to prefer the more rewarding action. Here we show that these publications are subject to at least one of two critical confounds and that most are subject to both. First, we show that even weak temporal correlations in the neuronal data may result in an erroneous identification of action-value representations. We demonstrate this by erroneously identifying action-value representations, both in simulations and in the neural activity recorded in unrelated experiments. Second, we show that the experiments and analyses designed to dissociate action-value representation from the representation of other decision variables cannot do so. Specifically, we show that neurons representing policy may be erroneous identified as representing action-values. We suggest different solutions to identifying action-value representation that are not subject to these confounds. Applying one of these solutions to previously identified action-value neurons in the basal ganglia we fail to detect action-value representations there. Thus, we conclude that the claim that striatal neurons encode action-values must await new experiments and analyses.
Genome build information is an essential part of genomic track files
Authors: Kanduri Chakravarthi , Domanska Diana , Hovig Eivind , Sandve Geir Kjetil 
Published: March 2017

AbstractGenomic locations are represented as coordinates on a specific genome build version, but the build information is frequently missing when coordinates are provided. It is essential to correctly interpret and analyse the genomic intervals contained in genomic track files. Here, we demonstrate that this crucial metadatum (or rather datum) is often isolated from the genomic track files in public repositories and journal articles, which could be a major time thief. We propose best practices to ensure that genome build version is always carried along with genomic track files. Although not a substitute to the best practices, we also provide a tool to predict the genome build version of genomic track files.
The genome of the contractile demospongeTethya wilhelmaand the evolution of metazoan neural signalling pathways
Authors: Francis Warren R. , Eitel Michael , Vargas Sergio , Adamski Marcin , Haddock Steven H.D. , Krebs Stefan , Blum Helmut , Erpenbeck Dirk , Wörheide Gert 
Published: March 2017

AbstractPorifera are a diverse animal phylum with species performing important ecological roles in aquatic ecosystems, and have become models for multicellularity and early-animal evolution. Demosponges form the largest class in sponges, but previous studies have relied on the only draft demosponge genome ofAmphimedon queenslandica. Here we present the 125-megabase draft genome of a contractile laboratory demospongeTethya wilhelma, sequenced to almost 150x coverage. We explore the genetic repertoire of transporters, receptors, and neurotransmitter metabolism across early-branching metazoans in the context of the evolution of these gene families. Presence of many genes is highly variable across animal groups, with many gene family expansions and losses. Three sponge classes show lineage-specific expansions of GABA-B receptors, far exceeding the gene number in vertebrates, while ctenophores appear to have secondarily lost most genes in the GABA pathway. Both GABA and glutamate receptors show lineage-specific domain rearrangements, making it difficult to trace the evolution of these gene families. Gene sets in the examined taxa suggest that nervous systems evolved independently at least twice and either changed function or were lost in sponges. Changes in gene content are consistent with the view that ctenophores and sponges are the earliest-branching metazoan lineages and provide additional support for the proposed clade of Placozoa/Cnidaria/Bilateria.
Protection of hot subsea risers by using thermally sprayed aluminium
Authors: Ce Nataly Araujo , Paul Shiladitya 
Published: March 2017

PurposeIn spite of the high interest in thermally sprayed aluminium (TSA) to protect offshore structures, pipelines, risers, etc., data correlating the exposure of TSA-coated steel in hot seawater to its performance are lacking. No information is available on the performance of TSA in hot seawater, especially when damaged. This paper aims to address this knowledge gap and report the corrosion performance of damaged TSA on carbon steel exposed to boiling synthetic seawater for different periods (up to 5,000 h). It also attempts to understand the mechanism of formation of calcareous deposits in boiling synthetic seawater by using various characterisation tools.Design/methodology/approachTwin wire arc spray was used to coat carbon steel specimens with commercially pure aluminium. Holiday was drilled on the coated surface to expose the underlying steel, amounting to 4 per cent of the specimen surface area. These specimens were then exposed to boiling synthetic seawater for different periods: 2, 68, 188, 335 and 5,000 h. During exposure, the potential was monitored (vs standard calomel electrode [SCE]) and linear polarisation resistance (LPR) method was used to calculate the corrosion rate (CR). After exposure, these specimens were analysed by using characterisation tools such as X-ray diffraction (XRD) and scanning electron microscope (SEM)/energy-dispersive X-ray spectroscopy (EDX).FindingsThe TSA-coated steel samples with 4 per cent holiday showed a CR of approximately 0.008-0.015 mm y−1and a stable potential (Ecorr) around −800 mV (SCE), when exposed to boiling synthetic seawater for approximately 5,000 h. Microstructural characterisation established that the deposits comprised brucite [Mg(OH)2] only (this is very different to what has been reported at ambient temperatures). The stable potentials obtained after 5,000 h suggest that the brucite layers provided effective corrosion mitigation. Thus, TSA seems to show the potential to protection hot carbon steel risers, even when damage exposing the external steel surface to the seawater is present.Originality/valueThe mechanism of calcareous deposit formation has been studied for many years, but most of the previously reported studies concentrate on low or ambient temperature behaviour. The reported studies mainly concentrate on the application of cathodic protection, rather than the effect of TSA. This is the first journal paper where the behaviour of damaged TSA in boiling synthetic seawater has been reported. The formation of brucite-only layer in the damaged area adjacent to the steel surface in boiling synthetic seawater is novel. And the mechanism of formation of this layer has been explained in the paper.
An institutional perspective on modernization and sex-appeal advertising
Authors: Leung Luk Chung , Chow Cheris W.C. , Wan Wendy W.N. , Lai Jennifer Y.M. , Fu Isabel , Fong Candy P.S. 
Published: March 2017

Purpose
Building on institutional theory, the purpose of this paper is to propose a framework for analyzing how consumer attitudes toward nudity in ads change as a result of modernization. Modernization is driven by the currents of pluralism and rationalism. The authors highlight the inherent contradiction of these two pillars and how this contradiction results in an inverted-U pattern in the relationship between level of modernization and consumer attitudes toward sex appeals. Consumers’ sexual permissiveness and their perceived insufficiency of regulatory control over sexual content in the mass media are the individual-level mediators of the two pillars.

Design/methodology/approach
The data were collected from three Chinese cities at different levels of modernization. A total of 811 college students from the three cities participated in the study.

Findings
The relationship between level of modernization and attitude favorability followed an inverted-U pattern. Female participants in the most modernized city possessed significantly less favorable attitudes to the ads than their male counterparts. Female and male participants were similar in their attitudes in the less modern cities. Sexual permissiveness mediated the relationship between modernization and male participants’ attitudes, but not with female participants’ attitudes. Perceived sufficiency of regulatory control over sexual content mediated the relationship between modernization and their attitudes among both male and female participants.

Originality/value
The paper makes an empirical contribution by testing the hypotheses regarding consumers responses to sex-appeal advertising with data collected from three Chinese cities at different levels of modernization. Additionally, it offers an institutional perspective on social attitude changes. Social attitude change is of great interest to researchers, but a systematic theoretical analysis is currently lacking.
The impact of perceived service quality dimensions on customer satisfaction
Authors: Kant Rishi , Jaiswal Deepak 
Published: March 2017

Purpose
In the present competitive scenario in the Indian banking industry, service quality has become one of the most important facets of interest to academic researchers. The purpose of this paper is to determine the dimensions of perceived service quality and investigate their impact on customer satisfaction in the Indian banking context, with special reference to selected public sector banks in India.

Design/methodology/approach
On the basis of the empirical study, the authors validate a measurement model using structural equation modeling for investigating the impact of perceived service quality dimensions on customer satisfaction. The study sample consists of 480 respondents in the National Capital Region (NCR) of India; the data were collected through a structured questionnaire utilizing a seven-point Likert scale while implementing a purposive sampling technique.

Findings
The perceived service quality dimensions identified were tangibility, reliability, assurance, responsiveness, empathy, and image. The empirical findings revealed that “responsiveness” was found to be the most significant predictor of customer satisfaction. On the other hand, “image” (corporate image) has a positive but the least significant relationship with customer satisfaction followed by all other constructs. The exception is “reliability,” which is insignificantly related to customer satisfaction in Indian public sector banks.

Research limitations/implications
The study cannot be generalized in the context of Indian banking sectors, as it only focused on the public sector. The findings of this study suggest that the six dimensions of perceived service quality model are a suitable instrument for evaluating bank service quality for public banks in India. Therefore, bank managers can use this model to assess the bank service quality in the context of Indian public sector banks.

Originality/value
There is dearth of research focusing on corporate image as a dimension of perceived service quality and its effect on customer satisfaction in the Indian banking context. Furthermore, similar studies were rarely found in the Indian context, especially within the public banking sector. Hence, this paper attempts to accomplish the research gap by empirically testing the satisfaction level of a large sample of the population in NCR toward six dimensions of perceived service quality rendered by selected public sector banks in India.
Improving throughput in a youth mental health service
Authors: Coates Dominiek , Howe Deborah 
Published: March 2017

PurposeThe discrepancy between increasing demand and limited resources in public mental health is putting pressure on services to continuously review their practices and develop innovative models of care that redress this discrepancy. To ensure the service models continue to meet the needs of all stakeholders, children and young people’s mental health (CYPMH) conducts regular reviews of its service models. Accordingly, the youth mental health (YMH) model at CYPMH has evolved significantly over time in response to the needs of young people and service demand. The purpose of this paper is to outline the findings of a recent review of the YMH service, and the subsequent changes to the service model.Design/methodology/approachInformed by a participatory action philosophy, feedback was sought from staff on the service model through a range of methods including a questionnaire, staff consultations through a working party and interviews. This feedback was used to redesign the model, which was then evaluated again.FindingsStaff identified a number of challenges with the service model and a range of service improvement solutions. The key issues included exceedingly high caseloads, workplace tensions, and fragmentation of the client journey. This paper outlines the primary solution to these key concerns, namely, the introduction of brief intervention (BI) as the entry point to the service.Originality/valueBI approaches provide a solution to overly high caseloads as the direct and focussed approach of BI generally reduces the number of sessions people need. BI is an important addition to other treatment options and should be seen as a valid component of the continuum of mental healthcare.
Potential facilitators and barriers to adopting standard treatment guidelines in clinical practice
Authors: Sharma Sangeeta , Pandit Ajay , Tabassum Fauzia 
Published: March 2017

Purpose
The purpose of this paper is to assess medicines information sources accessed by clinicians, if sources differed in theory and practice and to find out the barriers and facilitators to effective guideline adoption.

Design/methodology/approach
In all, 183 doctors were surveyed. Barriers and facilitators were classified as: communication; potential adopters; innovation; organization characteristics and environmental/social/economic context.

Findings
Most of the clinicians accessed multiple information sources including standard treatment guidelines, but also consulted seniors/colleagues in practice. The top three factors influencing clinical practice guideline adoption were innovation characteristics, environmental context and individual characteristics. The respondents differed in the following areas: concerns about flexibility offered by the guideline; denying patients’ individuality; professional autonomy; insights into gaps in current practice and evidence-based practice; changing practices with little or no benefit. Barriers included negative staff attitudes/beliefs, guideline integration into organizational structures/processes, time/resource constraints. Fearing third parties (government and insurance companies) restricting medicines reimbursement and poor liability protection offered by the guidelines emerged as the barriers. Facilitators include aligning organizational structures/processes with the innovation; providing leadership support to guide diffusion; increasing awareness and enabling early innovation during pre/in-service training, with regular feedback on outcomes and use.

Practical implications
Guideline adoption in clinical practice is partly within doctors’ control. There are other key prevailing factors in the local context such as environmental, social context, professional and organizational culture affecting its adoption. Organizational policy and accreditation standards necessitating adherence can serve as a driver.

Originality/value
This survey among clinicians, despite limitations, gives helpful insights. While favourable attitudes may be helpful, clinical adoption could be improved more effectively by targeting barriers.
Corporate philanthropy communication on donor websites
Authors: Chalmeta Ricardo , Viinikka Henna 
Published: March 2017

Purpose
This paper aims to examine whether companies engaging in corporate philanthropy, a component of corporate social responsibility (CSR), disclose information about such activities publicly on their websites, analyze whether there is a relation between the kind of charitable giving (in-kind donations or financial gifts), the number of donation types, or the industry sector the company belongs to, the mention on the company website and whether there is a relation between communicate company corporate philanthropy and communicate other company CSR issues.

Design/methodology/approach

The research methodology was descriptive statistics research method. The data were collected during the months of June and July 2013 from the websites of 141 companies that had recently engaged in corporate philanthropy.

Findings
The study found that, surprisingly, a considerable portion of companies practicing corporate philanthropy do not disclose that information on their websites. This was especially the case when donations were made with product instead of in cash.

Originality/value
This study quantifies the fact that many companies engage in CSR through corporate philanthropy but do not communicate those activities to a wider public. This can be seen as a missed opportunity to take advantage of a variety of positive effects that companies related to CSR benefit from. On the other hand, it can also be interpreted as a missed opportunity for the NGOs to encourage their donors to “come out” with their philanthropic activities.
Social presence and customer brand engagement on Facebook brand pages
Authors: Pongpaew Wimmala , Speece Mark , Tiangsoongnern Leela 
Published: March 2017

Purpose
Business use of social media is increasing rapidly as marketers aim to increase customer brand engagement (CBE) in brand communities to enhance the brand experience. However, use of social media for marketing communications is not well understood. This study aims to examine manager and user views of CBE and effects of perceived social presence (PSP) on CBE in a corporate Facebook environment.

Design/methodology/approach
Qualitative in-depth interviews are conducted with 18 users of corporate Facebook – i.e. those who visit corporate Facebook regularly – and four marketing managers whose companies operate Facebook pages. The industry is smart-information technology devices, and the cultural context is Thailand.

Findings
Corporate Facebook sites with high SP functions foster customer engagement on cognitive, emotional and behavioral levels. PSP enhances product knowledge and encourages return page visits. Thus, CBE and PSP build brand trust and loyalty. However, managers may need to focus more on the nature of the brand community beyond the corporate Facebook page.

Practical implications
Companies that enrich their corporate Facebook with SP features can encourage CBE. Consumers feel more informed about the brand and therefore feel more positively about it, which enhances the brand experience and brand trust. This holds even for lurkers who do not behaviorally engage on the Facebook page much, but who are active in the broader brand community.

Originality/value
This paper studies the relationship between PSP and CBE in a corporate Facebook environment, providing insights into how PSP influences CBE, which can enhance the customer’s brand experience and contribute to brand perceptions.
The four modes of coexistence in social systems
Authors: Nechansky Helmut 
Published: March 2017

Purpose
The paper aims to relate the four modes of coexistence of goal-orientated systems – conflict, hierarchy, the niche and cooperation – to static behavioral descriptions of social systems.

Design/methodology/approach
Analyzing the options for interactions of goal-orientated systems leads the four modes of coexistence. These show certain behavioral characteristics. Searching for these characteristics in selected behavioral descriptions in organizational theory, sociology, political science and system science allows relating them to certain modes.

Findings
In organizations, the four modes of coexistence show in general (Cameron and Quinn) and dyadic interaction patterns (Argyris). In sociology, they show in educational schemes preparing for specific modes (Bernstein) and in different exchange patterns (Polanyi). In political theory, the four modes of coexistence show in preferred policies of parties, in institutional development, in oligarch power politics (Winters) and in external policy. In system science, they show in problem solving strategies (Jackson) and “mindscapes” (Murayama).

Research limitations/implications
The analysis is restricted to static patterns leaving out dynamic developments, for example, in networks.

Practical implications
Together with previous investigations, the paper shows how behavioral descriptions ranging from psychology to politics correspond to the four modes of coexistence, and it suggests interrelations and alignments of the modes via various levels of societal organization.

Originality/value
The four modes of coexistence provide an unequivocal theoretical framework that allows finding parallels in behavioral descriptions ranging from psychology via sociology to politics.