bluuebunny/crossref_metadata_2025_split huggingface dataset:
High prevalence of HPV-56 and HPV-39 in Sari, Iran: an analysis of genotype distribution
Authors: Letafati Arash , Farahani Ali Vasheghani , Nasiri Mohammad Mostafa Baradaran , Pourmoein Hossein , Ardekani Omid Salahi , Ahoodashty Haniyeh , Hashemi-Soteh Mohammad Bagher , Dadgar Aniseh , Behshood Parisa , Azhar Iman Rezaee , Parsania Masoud 
Published: September 2024

Abstract
Background
Human papillomavirus (HPV) is responsible for the most common sexually transmitted infection, particularly among sexually active individuals. Understanding the geographical distribution and epidemiology of the most prevalent HPV genotypes is essential for developing effective prevention strategies. Consequently, this study aimed to examine the distribution of HPV genotypes among HPV-positive women and men in Sari, the capital city of Mazandaran province in northern Iran.

Materials and methods
HPV DNA was extracted (PZP Company, Molecular IVD, Iran) from genital and cervical samples of the study participants. Genotyping was conducted for 90 cases utilizing the High + Low Papilloma Strip test (Operon Company, Spain). Demographic data were statistically analyzed in correlation with the virological data (STATA version 17).

Results
Overall, 67.7% (61 out of 90) of the cases tested positive for HPV, with 75% of those being classified as high-risk. The participant group consisted of 92% females (83) and 8% males (7). The highest HPV prevalence, 75% (36), was observed in females and males aged under 31, with the majority of positive cases belonging to high-risk genotypes. The most frequently identified genotypes were HPV-11 (23%), HPV-6 (21%), HPV-56 (18%), HPV-39 (16%), HPV-16, HPV-91, and HPV-66 each comprising (14%). HPV-56 was the most common high-risk genotype, accounting for 11 cases (18%), followed by HPV-39, which was present in 10 cases (16%).

Conclusion
The prevalence of HPV infection was particularly high among individuals under the age of 31 for both genders, with men exhibiting a 100% infection rate. These findings emphasize the urgent need for targeted education aimed at the younger population and the implementation of infection control measures. Specifically, widespread HPV vaccination targeting HPV-6, HPV-11, HPV-39, and HPV-56 should be prioritized for the general population.
Defending the right to health in Gaza: a call to action by health workers
Authors: Mohammed Fatima , Elgailani Umniha Siddig Ahmed , Ibrahim Ali Sondos Yassir , Mohamed Razan Faisal Abdullah , Su Yin Elaine Tan , Bravo-Vasquez Martha L. 
Published: September 2024

AbstractThe ongoing conflict in Gaza has led to severe destruction of the health system and eventually its collapse. Moreover, multiple attacks on health workers were reported which led to obstacles in service delivery. The conflict has led to further humanitarian crises including shortage of food, water sanitation, and hygiene, and outbreaks of infectious diseases. About 2 million of Gaza’s population are internally displaced with the majority in Rafah. Rafah’s population has increased by 500% in less than four months. This has led to acute food severity in Gaza for the whole of the population. Moreover, the cut of UNRWA aid is expected to further expand the humanitarian crisis as over 2 million of the population depends on the aid.
The impact of body composition on functional recovery, mortality, and survival: a systematic review of research conducted in a cohort of stroke survivors
Authors: Ewah Patrick Ayi , Badaru Umaru Muhammad , Abba Muhammad Aliyu , Womboh Idoo 
Published: September 2024

Abstract
Background
The phrase obesity paradox after stroke appears to be a recent phenomenon and was first coined in the early 2000s; thereafter, there has been a growing controversy about the phenomenon, with many studies in favor and a few others against it. Notably, obesity a major risk factor for stroke is now regarded as global pandemic. The purpose of this study was to carry out a systematic review on the impact of body weight on functional recovery, mortality, and survival among stroke survivors.

Methods
We searched PubMed and Google scholar from January 2011 to 2022. Studies were recruited if they reported the impact of body weight on functional recovery, mortality, and survival among stroke survivors.

Results
A total of 284,699 subjects (30-studies) were included, and 2 were RCTs and a nested case–control study. Seventeen (n = 197,833, two on intravenous thrombolysis-IVT), and two studies (n = 2565) on body weight and outcome among stroke patients receiving insulin were in support of the obesity paradox. Nine studies (n = 79,451, four on IVT) were against the obesity paradox. For body weight and outcome of ischemic stroke patients treated with IVT, a total of six studies (n = 2940) four against and two in support of the obesity paradox. In addition, two studies (n = 4124) reported on WHR, WC, and BMI on mortality and outcome.

Conclusions
Overall, the odds were in favor of the obesity paradox among stroke patients with their first-time stroke with no report on second-time stroke. The underweight patients showed the worst unfavorable outcome and mortality. Insulin resistance is a major factor underpinning the presence of a paradox among stroke patients with diabetes receiving treatment with insulin therapy. We recommend that the nutritional status of stroke patients be taken into consideration during management. More studies especially on RCT should be conducted to determine the impact of body weight other that BMI on mortality and functional recovery among stroke survivor of African descent.
Feasibility of an antegrade-retrograde single-sheath inverse technique via vertical puncture in dysfunctional hemodialysis arteriovenous fistula angioplasty
Authors: Hasegawa Tetsuya , Tsuboi Masahiro , Takahashi Yuki , Endo Akira , Gotoh Yasuo 
Published: September 2024

Abstract
Background
Stenosis resulting in dysfunctional dialysis access may occur simultaneously on the anastomotic and central venous side. The purpose of this study was to retrospectively evaluate the feasibility of a single sheath inverse technique using the vertical puncture approach to perform bidirectional transvenous percutaneous transluminal angioplasty (PTA) from a single sheath for such dialysis access stenoses.

Materials and Methods
Twenty patients (26 cases; 13 males; median age, 74 [range: 50–89] years) who underwent PTA using the sheath inverse technique for dysfunctional arteriovenous fistula stenoses between April 2019 and June 2023 were included. All procedures were performed in an outpatient setting. A 4-cm sheath (4Fr, four cases; 5Fr, 19 cases; 6Fr, three cases) was inserted by vertical puncture through a cutaneous vein in the forearm (20 cases) or upper arm (six cases). After treating one side of the lesion, the sheath was reversed to treat the lesion on the opposite side. The vessel diameter at the sheath insertion site, the success rate of sheath inversion, the number of PTA balloon catheters used, the PTA success rate, adverse events, and primary and secondary patency rates up to one year after PTA were evaluated.

Results
The median diameter at the sheath indwelling site was 5.2 (range: 3.6–9.5) mm, and sheath inversion was successful in all cases, eliminating the need to place an additional sheath at another site for contralateral stricture treatment. The number of balloon catheters used was one and two in 17 (65%) and eight cases (31%), respectively, and three in one case wherein a drug-coated balloon was used. PTA was successful in all cases and major complications were not observed. However, in one case wherein a sheath had to be placed at the arterial needle puncture site, the skin was hard, leading to difficulty in inversion, and transient venous spasm occurred post-inversion. The primary patency rates at 3, 6 and 12 months after the PTA were 87.5%, 41.7%, and 20.8%, respectively. The secondary patency rates at 6 and 12 months were 100% and 75%, respectively.

Conclusion
The single-sheath inverse technique for arteriovenous fistulas was feasible without sheath withdrawal.

Graphical Abstract
Development and content validation of coordinate response measure (CRM) corpus in Kannada for informational masking measurement
Authors: Rachana Dhananjay , Neelamegarajan Devi 
Published: September 2024

Abstract
Background
Assessing informational masking (IM) involves various methods, broadly categorized as electrophysiological and behavioral approaches. In behavioral methods, researchers often use a range of stimulus types such as tone-in-noise masking, speech masking, music masking, gap detection, modulation masking, and spatial masking. The evaluation of speech perception in noisy conditions often utilizes the coordinate response measure (CRM), a publicly available test developed by Moore (AGARD conference proceedings 311, 1981). The objective of the study is to develop and content validate the Kannada coordinate response measure (CRM) sentences corpus for the information masking measurement.

Results
Stage 1: A total of thirty-eight call signs, eight colors, and eight numbers in the Kannada language were compiled and were given to 15 experts to select the appropriate stimuli. Those stimuli that satisfied the criteria of CVI ≥ 0.90 and CVR ≥ .90 were selected, which consisted of eight call signs, seven numbers, and five colors. Stage 2: By incorporating the chosen call signs, numbers, and colors, seven sentence structures were formulated and were subjected to content validation (criteria of CVI ≥ 0.90 and CVR ≥ .90). The sentence structure “(Call sign) iga (Color) bannada (Number) torsu” was finalized.
Stage 3: Eight speakers (four males and four females) recorded Kannada sentences of about 3.5 s each, which were evaluated by five audiologists for voice quality, rate, and speech clarity using a 4-point scale. The evaluation identified two male and two female speakers with the best recordings.
Stage 4: The final stage involved recording 235 sentences by the selected speakers, which were then assessed by two Kannada-speaking audiologists for face validity on various parameters, ensuring linguistic appropriateness and cultural relevance for inclusion in the final CRM corpus.

Conclusion
The resulting corpus, meticulously curated and content-validated, presents significant potential for advancing research and clinical assessment of informational masking within the Kannada-speaking community. Overall, the CRM’s exceptional performance in challenging listening environments, inherent adaptability across languages, versatility for different age and literacy levels, and effectiveness in speech-intelligibility testing with multiple simultaneous talkers due to its use of call signs underscores its value as a superior measurement tool, which can be used in IM measurement in Kannada-speaking population.
Exploring the associations between momentary cortisol levels and psychotic-like experiences in young adults: Results from a temporal network analysis of daily-life data
Authors: Grąźlewski Tomasz , Samochowiec Jerzy , Gelner Hanna , Gawęda Łukasz , Bogudzińska Bogna , Kowalski Krzysztof , Piotrowski Patryk , Misiak Błażej 
Published: September 2024

Abstract
Dysregulation of the hypothalamic–pituitary–adrenal (HPA) axis has been implicated in the development of psychosis and subthreshold psychotic symptoms commonly referred to as psychotic-like experiences (PLEs). The exact mechanisms linking the HPA axis responses with the emergence of PLEs remain unknown. The present study aimed to explore real-life associations between stress, negative affect, salivary cortisol levels (a proxy of the HPA axis activity) as well as PLEs together with their underlying cognitive biases (i.e., threat anticipation and aberrant salience). The study was based on the experience sampling method scheduled over 7 consecutive days in the sample of 77 drug-naïve, young adults (18–35 years). The saliva samples were collected with each prompt to measure cortisol levels. A temporal network analysis was used to explore the directed associations of tested variables. Altogether, 3234 data entries were analyzed. Data analysis revealed that salivary cortisol levels did not directly predict next-moment fluctuations of PLEs. However, higher salivary cortisol levels were associated with higher next-moment levels of PLEs through the effects on threat anticipation and negative affect. In turn, PLEs appeared to predict cortisol levels through the effects on negative affect and event-related stress. Negative affect and threat anticipation were the most central nodes in the network. There might be bidirectional associations between the HPA axis responses and PLEs. Threat anticipation and negative affect might be the most important mediators of these associations. Interventions targeting these mediators might hold promise for disrupting the connection between the HPA axis dysregulation and PLEs.
Determining Clinicopathologic Factors That Influence Treatment in Advanced Breast Cancer in Argentina After CDK4/6 Inhibitors
Authors: Waisberg Federico , Mandó Pablo , Almada Carolina , Kassis Naima , Mainella Andrea , Cermignani Luciano , Riggi María Cecilia , Winocur Melina , González Ramiro , Guercovich Andres , Ayala Natalia , Micheri Cristian , Ituarte Ana Carolina , González Mattos Lucía , Llugdar Pamela , Casalnuovo Mónica , Lutteral Maribel , Cinquini Sebastián , Mazzotta Alejandro , Lara Alcantara Janeth , Penayo Rosa , Gomez-Abuin Gonzalo 
Published: September 2024

PURPOSE The optimal treatment sequence for hormone receptor–positive (HR+)/human epidermal growth factor receptor 2–negative (HER2–) advanced breast cancer (ABC) after progression on first-line cyclin-dependent kinase 4/6 inhibitor (CDKi) and endocrine therapy is unclear. Clinical and biological factors influencing treatment choices and outcomes in the second-line setting need to be elucidated. MATERIALS AND METHODS This is a retrospective analysis of a real-world cohort including patients with HR+/HER2– ABC who received CDKi and endocrine therapy in the first-line setting and progressed, requiring second-line treatment. Clinical and biological factors were analyzed to evaluate their association with daily treatment decisions and the prognostic role of progression-free survival (PFS) in the second-line setting. RESULTS Two hundred thirty-five patients were included. Second-line treatments were hormone therapy (HT) based in 60% and chemotherapy based in 40% of patients. The second-line median PFS was 6.6 months, with no difference between treatment types. In multivariable analysis, postmenopausal status, lower Ki-67 expression, and non–de novo stage IV disease were associated with improved second-line (2L) PFS. Menopausal status significantly interacted with treatment type, with reduced PFS in premenopausal patients receiving HT-based treatments (4.7 v 8.7 months, P = .00045). CONCLUSION In our study, treatment decisions reflected the current algorithm incorporated in our clinical guidelines, and prior treatment response was the most relevant factor to determine 2L treatment decision. Menopausal status interacted with the subsequent therapy efficacy in this setting. Hence, we consider that menopausal status should be routinely evaluated in the subgroup analysis of clinical trials.
Real-World Outcomes of First-Line Treatment With Anti–PD(L)1-Based Combination Therapy for Nonsquamous Metastatic Non–Small Cell Lung Cancer: A Multiregional Chart Review in Europe, Japan, and the United States
Authors: Liu Stephen V. , Dasgupta Anandaroop , Latremouille-Viau Dominick , Rossi Carmine , Rai Pragya , Barlesi Fabrice , Leal Ticiana A. 
Published: September 2024

PURPOSE Anti–PD-1/PD(L)1-based combination therapy is the standard of care in first line (1L) for metastatic nonsquamous non–small cell lung cancer (mnsqNSCLC) without driver alterations. This study aimed to evaluate real-world clinical outcomes in this population. METHODS Eligible physicians in the United States, Europe, and Japan abstracted information from medical charts of eligible adult patients with mnsqNSCLC (without EGFR/ ALK, no known ROS1 alterations) who initiated 1L anti–PD(L)1-based combination therapy for mnsqNSCLC between 2017 and 2021. Kaplan-Meier analyses were used to assess overall survival (OS), time-to-treatment discontinuation (TTD), and real-world progression-free survival (rwPFS) after 1L initiation. RESULTS Overall, 142 physicians contributed deidentified data from 430 patients' medical charts. The distribution of PD-L1 expression levels was 31.2% with tumor proportion score (TPS) <1%, 42.3% with TPS 1%-49%, and 26.5% with TPS ≥50%. In 1L, patients received anti-PD(L)1 + chemotherapy (84.6%), anti-PD(L)1 + anti-CTLA4 with or without chemotherapy (11.9%), and anti-PD(L)1 + chemotherapy + anti-vascular endothelial growth factor receptor (3.5%). The median OS was 21.7 months (TPS <1%: 18.3 months; TPS 1%-49%: 21.6 months; TPS ≥50%: 24.0 months). The median TTD was 11.0 months (TPS <1%: 9.1 months; TPS 1%-49%: 10.9 months; TPS ≥50%: 12.2 months). The median rwPFS was 11.2 months (TPS <1%: 9.3 months; TPS 1%-49%: 11.1 months; TPS ≥50%: 13.2 months). CONCLUSION This study assessed the real-world clinical effectiveness of 1L anti–PD(L)1-based combination therapy for mnsqNSCLC. Results from this study were generally consistent with previous clinical trials and published real-world evidence in 1L mnsqNSCLC.
Influence of mode of birth on postpartum sexual function and quality of life among primiparous women in Ile-Ife, Nigeria
Authors: Ayamolowo Sunday Joseph , Adesoji Bukola Abimbola , Oluwatosin Omolabake Ruth 
Published: September 2024

Background/Aims Pregnancy and birth cause hormonal and bodily alterations that can have profound effects on women's sexual function and quality of life. The aim of this study was to evaluate the influence of mode of birth on postpartum sexual function and quality of life in primiparous women from health facilities in Ile-Ife, Nigeria. Methods This study used a descriptive design to explore women's sexual function and satisfaction from those attending selected healthcare facilities. Data were collected from 120 women recruited via convenience sampling, using a structured questionnaire between January and June 2023. Data were analysed using the Statistical Product of Service Solution (version 23) software; hypotheses were tested with Pearson's Chi-squared test at P<0.05. Results Women most commonly resumed sexual activities within 1 month of giving birth (58.3%). Greater proportions of women who had a spontaneous vaginal birth with episiotomy (26.3%), or vaginal birth without episiotomy (25.0%) reported poor postpartum quality of life than those who had a caesarean section (11.2%). Additionally, more women who had an episiotomy reported lower levels of sexual satisfaction than those who did not have an episiotomy (10.5% vs 0.0% reported lowest level of positive satisfaction; 2.6% vs 2.4% reported highest level of negative satisfaction). Sexual function and quality of life were significantly linked (P<0.001). Conclusions Sexual function and quality of life are an important element of postpartum women's health and wellbeing. Mode of birth affected women's postpartum quality of life, with vaginal birth and episiotomy resulting in less satisfaction and lower quality of life. Implications for practice Healthcare professionals working in maternity settings should work to prevent injury to the perineum during birth and provide education during the postpartum period to improve women's sexual function and quality of life.
What enhances the quality of death and dying? A perspective from patients with terminal cancer
Authors: Wajid Maria , Rajkumar Eslavath , Romate John 
Published: September 2024

Aim: This study aimed to determine which factors improve the quality of dying and death from the point of view of patients with cancer who are nearing the end of their lives. The goal was to find out what they think are necessary conditions for a good death and how they would like to be cared for and supported at the end of their lives. Methods: This study used an exploratory research approach. Purposive sampling was used to select 21 participants from two hospices in Bengaluru and Hyderabad (Karunashraya and Sparsh), and Karnataka Cancer Hospital in Bangalore, India. Semi-structured interviews were undertaken to obtain data from the patients. Thematic analysis was used to examine the data. Results: Four themes were identified: 1) Spirituality and religiosity, 2) socioemotional support, 3) Breaking silence about the stage of the disease and 4) Preparation for and embracing death. There were distinct sub-themes within some of these that were highlighted using quotes from the participants. Conclusions: The study provided a comprehensive understanding of end-of-life care, the criteria for a high-quality end of life, strategies for achieving it, and the quality of the dying process and death in advanced cancer patients. Studying patients' experiences will help inform a more robust intervention strategy and action plan to improve the quality of end-of-life care in the Indian community.
Status and Development Trends of Intelligent Manufacturing in China's Furnishings Industry
Authors: Xiong Xian-qing , Yuan Ying-ying , Fang Lu , Liu Hui , Wu Zhi-hui 
Published: September 2024

Abstract
This paper analyzes the transformation of manufacturing in China's furnishings industry and the status of intelligent manufacturing on the basis of the industry status quo, corporate development around custom furnishings and digital manufacturing, and management and control of manufacturing information. On the basis of an understanding of smart homes, the guiding ideology and key technology in intelligent manufacturing in the furnishings industry involve digital manufacturing. This article comprehensively analyzes the influences of intelligent manufacturing on the furnishings industry related to diverse structure, sales, service, and competition among enterprises. We propose that the development direction of the intelligent manufacturing of furnishings includes digital transformation, collaborative platform construction, and continued improvements to distribution. This article also provides new ideas for the development and transformation of the personally customized furnishings industry and offers implications for digital manufacturing in the furnishings industry in the future.
Influence of interpersonal relationship on subjective well-being of college students: The mediating role of psychological capital
Authors: Zhang Jinyong , Zhao Shouying , Deng Huaiqing , Yuan Chuan , Yang Zhi 
Published: September 2024

BackgroundNowadays, the contradiction between the rapid improvement of people’s material living standard and the loss of spiritual pursuit or the increase of pressure is becoming more and more serious.With the impact of the new corona-virus pandemic, the employment situation of college students is more severe. This leads to the growth of psychological problems and alienation behavior of college students. In the promoting positive psychology and enhancing the happiness of the whole people, the relationship between interpersonal relationship and subjective well-being of college students is an interesting and valuable research topic.MethodsThe structural model with AMOS21.0 was used to verify the mediating effect of psychological capital between interpersonal relationship distress and SWB from the survey data of 673 college students.ResultsThe interpersonal distress has a negatively correlated with psychological capital and SWB, while psychological capital has a positively correlated with SWB. Psychological capital has Partial mediating effect between interpersonal distress and SWB, and the indirect effect accounts for 57% of the total effect.ConclusionThis study indicates that schools should pay attention to education and intervention in psychological capital, except for strengthening knowledge and skill training of college students in how to communicate with others.