bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systemic lupus erythematosus in Spanish males: a study of the Spanish Rheumatology Society Lupus Registry (RELESSER) cohort
Authors: Riveros Frutos A , Casas I , Rúa-Figueroa I , López-Longo F J , Calvo-Alén J , Galindo M , Fernández-Nebro A , Pego-Reigosa J M , Olivé Marqués A 
Published: November 2016

Objective The objective of this study was to describe the demographic, clinical, and immunological manifestations of systemic lupus erythematosus (SLE) in male patients. Methods A cross-sectional, multicenter study was carried out of 3651 patients (353 men, 9.7%, and 3298 women, 90.2%) diagnosed with SLE, included in the Spanish Rheumatology Society SLE Registry (RELESSER). Results Mean ages (18–92 years) of symptom onset were 37 (SD 17) years (men) and 32 (SD 14) years (women). Male/female ratio was 1/9. Age of onset of symptoms and age at diagnosis were higher in men than in women ( p < 0.001). Males were diagnosed earlier than females (p = 0.04) and had more cardiovascular comorbidities ( p < 0.001). Two hundred and thirty-six males (68%) with SLE required hospitalization in comparison with 1713 females (53%) ( p < 0.001). During follow-up, 208 patients died: 30 men (9.3%) and 178 women (5.9%) ( p = 0.02). As regards clinical manifestations, loss of weight ( p = 0.01), lymphadenopathies ( p = 0.02), and splenomegaly ( p = 0.02) were more common in male patients. Female patients were more likely to have inflammatory rash, alopecia, and arthritis ( p < 0.05). As for lung involvement, men with SLE had more pleural fibrosis ( p < 0.001) and pulmonary embolism ( p = 0.01). However, Raynaud’s phenomenon was more common in women (35%) than in men (23.7%) ( p < 0.001); lupus nephritis was more common in men, being present in 155 (44.8%) of males versus 933 (29%) of females ( p < 0.001). Multivariate analysis showed that SLE patients with a high Charlson index (more than 3 points) and age > 50 years had a higher mortality (odds ratios 3.6 and 2.1, respectively). Furthermore, SLE patients who developed pulmonary hemorrhage, pulmonary hypertension, psychiatric involvement, complement deficiency, and hemophagocytic syndrome also had higher mortality, regardless of gender. Conclusion Patients with SLE over the age of 50 years have an increased risk of mortality. In Caucasians, age at diagnosis and symptom onset is higher in men than in women. The diagnostic delay is shorter in men. Male SLE patients present more cardiovascular comorbidities, and also more serositis, adenopathies, splenomegaly, renal involvement, convulsion, thrombosis, and lupus anticoagulant positivity than women.
Primary trauma care curriculum: A qualitative analysis of impediments to improvement
Authors: Dickason Robert M , Cioè-Peña Eric , Chisolm-Straker Makini 
Published: November 2016

Objectives In 2014, the primary trauma care curriculum was delivered at a national trauma center in San Salvador, El Salvador. A quantitative analysis demonstrated that subsequent incorporation of primary trauma care algorithms did not occur. The purpose of this qualitative analysis is to explore why the delivery of the primary trauma care curriculum did not have a measurable effect on provider observance of primary trauma care algorithms. Methods Key informant interviews of primary trauma care instructors and students, trauma care observers, and hospital administrators involved in the delivery of the primary trauma care curriculum were conducted in February 2015. Interview transcripts were analyzed qualitatively using a grounded-theory approach and thematic analysis for insights and common themes. Results Four common themes emerged to explain why adherence to primary trauma care algorithms did not improve: Primary Trauma Care course delivery problems, insufficient equipment, insufficient nurse training, and unsystematic team response. Conclusions Despite the delivery of the primary trauma care curriculum, adherence to the primary trauma care algorithms did not improve as a result of problems integral to the primary trauma care model—including the teach-the-teachers method of curriculum dissemination—as well as local conditions at this hospital. These findings suggest that an isolated educational intervention may not be successful unless the host institution is able to commit to the implementation of the educational material in an ongoing and comprehensive fashion.
Subarachnoid Hemorrhage and Long-Term Stroke Risk After Traumatic Brain Injury
Authors: Morris Nicholas A. , Cool Joséphine , Merkler Alexander E. , Kamel Hooman 
Published: November 2016

Background: Recent studies suggest that traumatic brain injury (TBI) is a risk factor for subsequent ischemic stroke, even years after the initial insult. The mechanisms of the association remain unclear. The presence of traumatic subarachnoid hemorrhage (tSAH) may mediate the effect of TBI on long-term stroke risk, as it has previously been linked to short-term vasospasm and delayed cerebral ischemia. Methods: Using administrative claims data, we conducted a retrospective cohort study of acute care hospitalizations. Patients discharged with a first-recorded diagnosis of tSAH were followed for a primary diagnosis of stroke. They were matched to patients with TBI but not tSAH. Cox proportional hazards modeling was used to assess the association between tSAH and stroke while adjusting for covariates. Results: We identified 40 908 patients with TBI (20 454 patients with tSAH) who were followed for a mean of 4.3 + 1.8 years. A total of 531 had an ischemic stroke after discharge. There was no significant difference in stroke risk between those with tSAH (1.79%; 95% confidence interval [CI] 1.54%-2.08%) versus without tSAH (2.12%; 95% CI 1.83%-2.44%). The same pattern was found in adjusted analyses even when the group was stratified by age-group or by proxies of TBI severity. Conclusions: Our findings do not support a role of tSAH in mediating the association between TBI and protracted stroke risk. Further study is required to elucidate the mechanisms of long-term increased stroke risk after TBI.
Differences in outcome of patients with syncytial variant Hodgkin lymphoma compared with typical nodular sclerosis Hodgkin lymphoma
Authors: Sethi Tarsheen , Nguyen Van , Li Shaoying , Morgan David , Greer John , Reddy Nishitha 
Published: November 2016

Background: Nodular sclerosis Hodgkin lymphoma (NS-HL) is the most common subtype of HL and usually has a good prognosis. A variant of NS, the syncytial variant (SV) has well-established histopathologic features but little is known about its clinical behavior. Small case series have suggested that SV patients present with advanced disease and have a comparatively aggressive course. The objective of this study was to determine the clinical characteristics and outcome of SV patients Methods: A total of 167 adult patients with NS-HL including 43 patients with SV and 124 patients with typical NS (t-NS) were included in our analysis following institutional review board (IRB) approval. The Kaplan–Meier method was used to calculate the progression-free survival (PFS) and overall survival (OS). Log-rank test was used to determine the differences in survival. Results: Of the 167 patients, 43 were confirmed as SV based on morphology and immunophenotype. Doxorubicin, bleomycin, vinblastine and dacarbazine (ABVD) was the most frequent induction regimen administered in 91% of all patients. The rate of complete response (CR) in the SV group was 74% versus 87% in the t-NS group ( p = 0.05). At 49 months follow up, the PFS was 17 months in the SV group and not reached in the t-NS group [ p < 0.0001; hazard ratio (HR) = 3.695; 95% confidence interval (CI) = 3.0, 11.07]. The median OS was not reached in both groups ( p = 0.32). Conclusions: Our results show that SV histology represents a poor risk group with lower CR rate and shorter PFS and this should be considered in the risk stratification of classical HL patients.
Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics?
Authors: Murray Robin M. , Quattrone Diego , Natesan Sridhar , van Os Jim , Nordentoft Merete , Howes Oliver , Di Forti Marta , Taylor David 
Published: November 2016

SummaryPatients who recover from an acute episode of psychosis are frequently prescribed prophylactic antipsychotics for many years, especially if they are diagnosed as having schizophrenia. However, there is a dearth of evidence concerning the long-term effectiveness of this practice, and growing concern over the cumulative effects of antipsychotics on physical health and brain structure. Although controversy remains concerning some of the data, the wise psychiatrist should regularly review the benefit to each patient of continuing prophylactic antipsychotics against the risk of side-effects and loss of effectiveness through the development of supersensitivity of the dopamine D2 receptor. Psychiatrists should work with their patients to slowly reduce the antipsychotic to the lowest dose that prevents the return of distressing symptoms. Up to 40% of those whose psychosis remits after a first episode should be able to achieve a good outcome in the long term either with no antipsychotic medication or with a very low dose.
Être immortel à Paris Violence et prophétie durant la Révolution française
Authors: Solans Francisco Javier Ramón 
Published: October 2016

Résumé
L’objectif de cet article est de réfléchir à la relation entre événement et prophétie à l’époque de la Révolution française à travers le cas de Catherine Théot et son activité prophétique à Paris dans la seconde moitié du XVIIIe siècle. Face à une apparente immobilité, nous verrons que ses prophéties étaient en constante transformation et évolution, ce qui eut pour conséquence des discours hybrides et nourris d’influences variées tels que le jansénisme ou les discours révolutionnaires. L’affaire Théot permet de réfléchir à l’interprétation surnaturelle qui a été faite de la Révolution française. Ses prophéties apparaissent dans ce contexte comme une réponse aux besoins émotionnels provoqués par l’instabilité politique, la peur de la guerre, la violence politique et les changements religieux. Finalement, l’article met en évidence l’existence d’un discours religieux en marge de la dialectique entre révolution et contre-révolution bien qu’il y soit intimement lié par le poids des guerres révolutionnaires et de la Terreur.
ASSESSMENT OF MANGROVE FOREST DEGRADATION THROUGH CANOPY FRACTIONAL COVER IN KARIMUNJAWA ISLAND, CENTRAL JAVA, INDONESIA
Authors: Kamal Muhammad , Hartono Hartono , Wicaksono Pramaditya , Adi Novi Susetyo , Arjasakusuma Sanjiwana 
Published: October 2016

The Karimunjawa Islands mangrove forest has been subjected to various direct and indirect human disturbances in the recent years. If not properly managed, this disturbance will lead to the degradation of mangrove habitat health. Assessing forest canopy fractional cover (fc) using remote sensing data is one way of measuring mangrove forest degradation. This study aims to (1) estimate the forest canopy fc using a semi-empirical method, (2) assess the accuracy of the fc estimation and (3) create mangrove forest degradation from the canopy fc results. A sample set of in-situ fc was collected using the hemispherical camera for model development and accuracy assessment purposes. We developed semi-empirical relationship models between pixel values of ALOS AVNIR-2 image (10m pixel size) and field fc, using Enhanced Vegetation Index (EVI) as a proxy of the image spectral response. The results show that the EVI provides reasonable estimation accuracy of mangrove canopy fc in Karimunjawa Island with the values ranged from 0.17 to 0.96 (n = 69). The low fc values correspond to vegetation opening and gaps caused by human activities or mangrove dieback. The high fc values correspond to the healthy and dense mangrove stands, especially the Rhizophora sp formation at the seafront. The results of this research justify the use of simple canopy fractional cover model for assessing the mangrove forest degradation status in the study area. Further research is needed to test the applicability of this approach at different sites.
Aerospike
Authors: Srinivasan V. , Bulkowski Brian , Chu Wei-Ling , Sayyaparaju Sunil , Gooding Andrew , Iyer Rajkumar , Shinde Ashish , Lopatic Thomas 
Published: November 2016

In this paper, we describe the solutions developed to address key technical challenges encountered while building a distributed database system that can smoothly handle demanding real-time workloads and provide a high level of fault tolerance. Specifically, we describe schemes for the efficient clustering and data partitioning for the automatic scale out of processing across multiple nodes and for optimizing the usage of CPUs, DRAM, SSDs and networks to efficiently scale up performance on one node.
The techniques described here were used to develop Aerospike (formerly Citrusleaf), a high performance distributed database system built to handle the needs of today's interactive online services. Most real-time decision systems that use Aerospike require very high scale and need to make decisions within a strict SLA by reading from, and writing to, a database containing billions of data items at a rate of millions of operations per second with sub-millisecond latency. For over five years, Aerospike has been continuously used in over a hundred successful production deployments, as many enterprises have discovered that it can substantially enhance their user experience.
The MemSQL query optimizer
Authors: Chen Jack , Jindel Samir , Walzer Robert , Sen Rajkumar , Jimsheleishvilli Nika , Andrews Michael 
Published: November 2016

Real-time analytics on massive datasets has become a very common need in many enterprises. These applications require not only rapid data ingest, but also quick answers to analytical queries operating on the latest data. MemSQL is a distributed SQL database designed to exploit memory-optimized, scale-out architecture to enable real-time transactional and analytical workloads which are fast, highly concurrent, and extremely scalable. Many analytical queries in MemSQL's customer workloads are complex queries involving joins, aggregations, sub-queries, etc. over star and snowflake schemas, often ad-hoc or produced interactively by business intelligence tools. These queries often require latencies of seconds or less, and therefore require the optimizer to not only produce a high quality distributed execution plan, but also produce it fast enough so that optimization time does not become a bottleneck.
In this paper, we describe the architecture of the MemSQL Query Optimizer and the design choices and innovations which enable it quickly produce highly efficient execution plans for complex distributed queries. We discuss how query rewrite decisions oblivious of distribution cost can lead to poor distributed execution plans, and argue that to choose high-quality plans in a distributed database, the optimizer needs to be distribution-aware in choosing join plans, applying query rewrites, and costing plans. We discuss methods to make join enumeration faster and more effective, such as a rewrite-based approach to exploit bushy joins in queries involving multiple star schemas without sacrificing optimization time. We demonstrate the effectiveness of the MemSQL optimizer over queries from the TPC-H benchmark and a real customer workload.
Exploratory querying of extended knowledge graphs
Authors: Yahya Mohamed , Berberich Klaus , Ramanath Maya , Weikum Gerhard 
Published: November 2016

Knowledge graphs (KGs) are important assets for search, analytics, and recommendations. However, querying a KG to explore entities and discover facts is difficult and tedious, even for users with skills in SPARQL. First, users are not familiar with the structure and labels of entities, classes and relations. Second, KGs are bound to be incomplete, as they capture only major facts about entities and their relationships and miss out on many of the more subtle aspects.
We demonstrate TriniT, a system that facilitates exploratory querying of large KGs, by addressing these issues of "vocabulary" mismatch and KG incompleteness. TriniT supports query relaxation rules that are invoked to allow for relevant answers which are not found otherwise. The incompleteness issue is addressed by extending a KG with additional text-style token triples obtained by running Open IE on Web and text sources. The query language, relaxation methods, and answer ranking are extended appropriately. The demo shows automatic query relaxation and has support for interactively adding user-customized relaxations. In both situations, the demo provides answer explanations and offers additional query suggestions.
Business plan for a Zen garden
Authors: Žibrat Maja , Pažek Karmen , Weingerl Vesna 
Published: November 2016

AbstractThe placement of a theme park in the form of a Zen garden, as a business opportunity in the Slovenian rural area, is discussed. The design of the garden, with all the major points of a standard business plan, is accurately presented, with a description of the business, branch, and services, market analysis, marketing strategy, financial projections, and a plan of the work and activities. The financial aspect is presented as the amount of investment, net present value, and internal rate of return. The amount of investment is estimated at € 14.891, which should be reimbursed within 4 years of operations. The estimated internal rate of return is estimated at 16.86%. Part of the study is the market analysis - conduction of a survey into knowledge of, and interest in, Zen and Zen gardens. The principles of landscape ecology are respected, as the Zen garden would be set in the woods and will blend seamlessly into the landscape.
Impact of various types of anti-hail nets on light exposure in orchards and quality parameters of apples– a rewiev
Authors: Brglez Sever Marinka , Tojnko Stanislav , Unuk Tatjana 
Published: November 2016

Abstract The new Common Agricultural Policy (CAP) has been designed to shrink funds that Hungarian agricultural reform will in Nowadays, anti-hail nets are a part of basic equipment in a modern apple orchards. They decrease the risks of apple production and thus allow regular and quality apple harvest. Colours of nets differently obstruct the passing of light through the net, which directly affects some quality parameters of the yield, especially the fruit skin colour. The article includes a brief overview of studies associated with the impact of light exposure under different types of anti-hail nets on quality of apple fruits, as well as investigations which deal with adaptation of various technological measures, such as the use of reflective ground foil. A part of data from the existing literature explains the effect of anti-hail net usage on forming a microclimate under the net, and consequently, its effect on the development and dynamics of diseases and pests.
Modeling and Designing Acoustical Conditions of the Interior - Case Study
Authors: Kostek Bozena , Laskowski Sebastian , Mizgier Karolina 
Published: November 2016

Abstract
The primary aim of this research study was to model acoustic conditions of the Courtyard of the Gdańsk University of Technology Main Building, and then to design a sound reinforcement system for this interior. First, results of measurements of the parameters of the acoustic field are presented. Then, the comparison between measured and predicted values using the ODEON program is shown. Collected data indicate a long reverberation time which results in poor speech intelligibility. Then, a thorough analysis is perform to improve the acoustic properties of the model of the interior investigated. On the basis of the improved acoustic model two options of a sound reinforcement system for this interior are proposed, and then analyzed. After applying sound absorbing material it was noted that the predicted speech intelligibility increased from bad/poor rating to good category.
Acoustic Scattering of 3D Complex Systems Having Random Rough Surfaces by Scalar Integral Equations
Authors: Guel-Tapia Juan Antonio , Villa-Villa Francisco , Mendoza-Suarez Alberto , Pérez-Aguilar Hector 
Published: November 2016

Abstract
We propose a numerical surface integral method to study complex acoustic systems, for interior and exterior problems. The method is based on a parametric representation in terms of the arc’s lengths in curvilinear orthogonal coordinates. With this method, any geometry that involves quadric or higher order surfaces, irregular objects or even randomly rough surfaces can be considered. In order to validate the method, the modes in cubic, spherical and cylindrical cavities are calculated and compared to analytical results, which produced very good agreement. In addition, as examples, we calculated the scattering in the far field and the near field by an acoustic sphere and a cylindrical structure with a rough cross-section.
Media convergence and publicness: Towards a modular and iterative approach to online research ethics
Authors: Spilioti Tereza 
Published: November 2016

AbstractThe aim of the article is to build a bridge between assumptions about publicness and ethics in traditional (mass) media research and similar issues pertaining to research ethics in so-called new media environments. The article starts off with unpacking ‘publicness’ as defined in authoritative ethical guidelines that regulate research on (and through) media. It points to the challenges media convergence–and, particularly, the increasingly multimodal, multiauthored and multimedial content of websites–have brought to perceptions of publicness, as previously understood in mass media research. With reference to language-focused research on multilingual digital writing in such contexts, I critically engage with ethical tensions related to collecting and analysing internet data, on the one hand, and presenting and publishing data extracts from new media contexts, on the other. Drawing on modularity as a key organising principle of web design and discourse, the article proposes a modular and iterative approach to research ethics that takes into account the complex and fluid configuration of web environments and attends to the conditions of multiple authorship and multiple publics that are increasingly typical of such contexts.
Risk-Averse Managers, Labour Market Structures, Public Policies and Discrimination
Authors: Picault Julien 
Published: November 2016

AbstractThis article presents a model to analyze the effects of first and second-moment statistical discrimination on the labour market. Second-moment statistical discrimination occurs when risk-averse managers make decisions regarding wage and hiring based on productivity variances. We provide a framework exploring managers’ discrimination based on differences in average productivity and in variance of productivity. Furthermore, since discrimination is composed of two types (wage and hiring discrimination), our model allows for the interdependence between hiring practices and wages. Using our model, we examine the effects of various anti-discrimination policies along with changes to the labour market structure. We show that managers’ behaviour may be driven by anti-discrimination policies and labour market structures. A firm reduces hiring when required to implement anti-discrimination policies to address wage inequality. A firm applying policies to promote employment equity must stimulate minority participation. A change in labour market structure does not alter the efficiency of policies promoting employment equity, but it does alter the efficiency of policies aimed at reducing wage differences.