bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retinal pigment epithelium adenoma in vitreous fluid cytology
Authors: John Sandhya , Lew Madelyn 
Published: July 2017

AbstractOcular cytology specimens are relatively uncommon, adding to the difficulty of their evaluation by cytopathologists. While melanomas account for a majority of primary intraocular pigmented lesions, other diagnostic considerations must be included in the differential. This brief report highlights a case of a pigmented ocular lesion in a 24‐year‐old man and key morphologic, immunohistochemical, and clinical differences between melanoma, melanocytoma, choroidal nevus, and retinal pigment epithelium (RPE) adenoma.
Progression of skin autofluorescence of AGEs over 4 years in patients with type 1 diabetes
Authors: Rajaobelina Kalina , Helmer Catherine , Vélayoudom‐Céphise Fritz‐Line , Nov Sovanndany , Farges Blandine , Pupier Emilie , Blanco Laurence , Hugo Marie , Gin Henri , Rigalleau Vincent 
Published: July 2017

AbstractBackgroundThe deposit of advanced glycation end‐products is involved in diabetic complications. It can be evaluated by measuring the skin autofluorescence (sAF). We searched whether sAF progressed over 4 years in type 1 diabetes and analysed its relationship with the development of nephropathy.MethodsTwo measurements of skin autofluorescence (sAF) were completed on 154 patients during years 2009 and 2013. Baseline factors associated with the progression of sAF were analysed by multivariate regression analysis. The relations among sAF progression, microalbuminuria, and impaired estimated glomerular filtration rate (eGFR) were analysed by logistic regression analysis.ResultsThe patients were 51 ± 16 years old, with duration of diabetes of 23 ± 13 years, HbA1c: 7.7 ± 1.0%, 20.7% were treated by continuous subcutaneous insulin infusion (CSII).The sAF progressed by +18.1% over 4 years. Two interacting (P = .04) variables were associated with the later progression of sAF: mildly impaired eGFR and treatment by CSII. The patients with mildly impaired eGFR had the highest progression of sAF (+11.5% P = .01). Continuous subcutaneous insulin infusion was associated with a reduced progression of sAF in patients without kidney impairment (ß = −7.2%, P = .01). A +10% progression of sAF during the follow‐up was associated with more microalbuminuria: OR = 1.45, P = .02, and more mildly impaired eGFR (<90 mL/min/1.73 m2): OR 1.22, P = .03 at 4 years of follow‐up.ConclusionsThe skin autofluorescence of advanced glycation end‐products progresses in patients with type 1 diabetes, more if they have diabetic nephropathy, less if they are treated by continuous subcutaneous insulin infusion. This progression is associated with the development of nephropathy.
Predation risk and abiotic habitat parameters affect personality traits in extremophile populations of a neotropical fish (Poecilia vivipara)
Authors: Sommer‐Trembo Carolin , Petry Ana Cristina , Gomes Silva Guilherme , Vurusic Sebastijan Martin , Gismann Jakob , Baier Jasmin , Krause Sarah , Iorio Julia de Araujo Cardoso , Riesch Rüdiger , Plath Martin 
Published: July 2017

AbstractUnderstanding whether and how ambient ecological conditions affect the distribution of personality types within and among populations lies at the heart of research on animal personality. Several studies have focussed on only one agent of divergent selection (or driver of plastic changes in behavior), considering either predation risk or a single abiotic ecological factor. Here, we investigated how an array of abiotic and biotic environmental factors simultaneously shape population differences in boldness, activity in an open‐field test, and sociability/shoaling in the livebearing fish Poecilia vivipara from six ecologically different lagoons in southeastern Brazil. We evaluated the relative contributions of variation in predation risk, water transparency/visibility, salinity (ranging from oligo‐ to hypersaline), and dissolved oxygen. We also investigated the role played by environmental factors for the emergence, strength, and direction of behavioral correlations. Water transparency explained most of the behavioral variation, whereby fish from lagoons with low water transparency were significantly shyer, less active, and shoaled less than fish living under clear water conditions. When we tested additional wild‐caught fish from the same lagoons after acclimating them to homogeneous laboratory conditions, population differences were largely absent, pointing toward behavioral plasticity as a mechanism underlying the observed behavioral differences. Furthermore, we found correlations between personality traits (behavioral syndromes) to vary substantially in strength and direction among populations, with no obvious associations with ecological factors (including predation risk). Altogether, our results suggest that various habitat parameters simultaneously shape the distribution of personality types, with abiotic factors playing a vital (as yet underestimated) role. Furthermore, while predation is often thought to lead to the emergence of behavioral syndromes, our data do not support this assumption.
A High‐Frequency Cycloconverter Based on a Phase‐Shift Control Method
Authors: KOMEDA SHOHEI , FUJITA HIDEAKI 
Published: July 2017

SUMMARYThis paper proposes a new control method for a high‐frequency cycloconverter consisting of two half‐bridge inverters and a series–resonant circuit. This cycloconverter acts as an ac‐to‐ac direct power conversion circuit without any dc stage. This circuit does not require a diode bridge rectifier, and thus, can be used to reduce forward voltage drops and power losses in the diodes. A new phase‐shift control method is proposed to regulate the capacitor voltage in each half‐bridge inverter and to achieve zero‐voltage switching. The proposed phase‐shift control is theoretically discussed and is also verified by an experimental circuit consisting of superjunction power MOSFETs. As a result, the proposed high‐frequency cycloconverter exhibits a good power conversion efficiency as high as 97.7% at the rated power of 1.3 kW.
Data privacy management and data quality monitoring in the German Centre for Cardiovascular Research's multicentre TranslatiOnal Registry for CardiomyopatHies (DZHK‐TORCH)
Authors: Schwaneberg Thea , Weitmann Kerstin , Dösch Andreas , Seyler Claudia , Bahls Thomas , Geidel Lars , Stahl Dana , Lee Mahsa , Kraus Monika , Katus Hugo A. , Hoffmann Wolfgang 
Published: July 2017

AbstractAimsThe multicentric TranslatiOnal Registry for CardiomyopatHies (TORCH) of the German Centre for Cardiovascular Research aims to recruit 2300 patients with non‐ischemic cardiomyopthies.Methods and resultsThe investigations were performed after standard operating procedures. The data are collected in standardized electronic case report forms provided by the data holding of the central data management of the German Centre for Cardiovascular Research using secuTrial (interActive Systems GmbH, Berlin, Germany). The personal‐identifying data and informed consent are collected, stored, and quality‐checked by the independent Trusted Third Party in Greifswald. The quality management of the medical data is performed by the data and quality centre Greifswald. In December 2014, the recruitment for TORCH has started. Currently, data and biomaterial from about 1397 patients and more than 74 500 biomaterial aliquots were collected. Regular study centre‐specific quality reports address completeness and plausibility of data and provide detailed information about current missing or implausible data entries to improve the data quality by using a query management in addition.ConclusionsA regular quality control and reporting improve the data quality in TORCH and will support high‐quality data analysis and the translation of research results into routine care.
Highly Sensitive Dopamine Detection Using a Bespoke Functionalised Carbon Nanotube Microelectrode Array
Authors: Clark James , Chen Ying , Hinder Steven , Silva S. Ravi P. 
Published: July 2017

AbstractUnderstanding how the brain works requires developing advanced tools that allow measurement of bioelectrical and biochemical signals, including how they propagate between neurons. The introduction of nanomaterials as electrode materials has improved the impedance and sensitivity of microelectrode arrays (MEAs), allowing high quality recordings of single cells in situ using electrode diameters of ≤20 μm. MEAs also have the potential to measure electroactive biological molecules in situ, such as dopamine, a neurotransmitter in the nervous system. Thus, this work focused on fabricating a functionalised carbon nanotube (CNT)‐based MEA to demonstrate its potential for future measurement of small signals generated from excitable cells. To this end, the functionalised CNT MEA has recorded one of the lowest electrochemical interfacial impedances available in the literature, 2.8±0.2 kΩ, for an electrode of its geometric surface area. Electrochemical detection of dopamine revealed again one of the best sensitivity values per area available in the literature, 9.48 μA μM−1 mm−2. Additionally, a limit of detection of 7 nM was recorded for dopamine using the functionalised CNT MEA, with selectivity against common electrochemical interferents such as ascorbic acid. These results indicate improvement beyond currently available MEAs, along with the feasibility of using these devices for multi‐site detection of physiologically relevant electroactive biomolecules.
Nanoporous Gold Microelectrode: A Novel Sensing Platform for Highly Sensitive and Selective Determination of Arsenic (III) using Anodic Stripping Voltammetry
Authors: Jaramillo Darío Xavier Orellana , Sukeri Anandhakumar , Saravia Lucas P.H. , Espinoza‐Montero Patricio Javier , Bertotti Mauro 
Published: July 2017

AbstractA home‐made gold microelectrode (Au‐μE) was fabricated and its surface was modified with nanoporous gold structures via a facile electrochemical approach (anodization followed by electrochemical reduction method). The fabricated nanoporous Au microelectrode (NPG‐μE) was used as a sensor probe for the determination of As(III) in 1.0 mol L−1 HCl solution using square wave anodic stripping voltammetry (SWASV) technique. Field emission scanning electron microscopy (FE‐SEM) and cyclic voltammetry were used to characterize the surface morphology and assess the electrochemical surface area and the roughness factor of the NPG‐μE. SWASVs recorded with the NPG‐μE in As(III) solutions indicated linear behaviour in the concentration ranges of 10–200 μg L−1 and 2–30 μg L−1, with regression coefficients of 0.996 and 0.999 at a deposition time of 120 s, respectively. The limit of detection (LOD) was found to be 0.62 μg L−1 with high sensitivity of 29.75 μA (μg L−1)−1 cm−2. Repeatability and reproducibility were also examined and values were determined as 3.2 % and 9.0 %. Negligible interference from major interfering copper ion was noticed, revealing the excellent anti‐interference property of the proposed sensing platform. The developed NPG‐μE was successfully used for As(III) determination in tap water samples.
A new pancryptodiran turtle from the Late Jurassic of Poland and palaeobiology of early marine turtles
Authors: Szczygielski Tomasz , Tyborowski Daniel , Błażejowski Błażej 
Published: July 2017

Although Western Europe has yielded numerous Jurassic turtle taxa, several represented by cranial material or complete skeletons, the fossil record of the Jurassic turtles remains scarce to the north and east from Germany. Although some Late Jurassic testudinates were historically described from Poland, they were, thus far, represented by fragmentary remains that never were properly figured or described in detail. Therefore, very little is known about the mid‐Mesozoic diversity of turtles in that region of the continent. A new pancryptodiran turtle genus and species, Owadowia borsukbialynickae, is described from the uppermost Jurassic (Tithonian, ca. 148 Ma) carbonate sediments of the Kcynia Formation in Owadów‐Brzezinki Quarry, near Tomaszów Mazowiecki in central Poland. The lower jaw morphology and palaeoecological setting inhabited by the new genus and species, together with the trophic relationships of the Jurassic pancryptodiran turtles, are discussed in an attempt to determine the potential range of mode of life of O. borsukbialynickae. We propose that the new specimen belongs to a new durophagous pancryptodiran turtle taxon. O. borsukbialynickae might have spent considerable time in the marine environment and specialized on eating hard‐shelled invertebrates like bivalves and decapod crustaceans, common to that setting.
Multiplex PCR scheme for variant plasmid mediated class C β‐lactamase typing
Authors: Chuong Le Van , Prachayasittikul Virapong , Isarankura Na Ayudhya Chartchalerm , Lawung Ratana 
Published: July 2017

BackgroundAn increasing of prevalence and diversification of plasmid‐mediated AmpC (pAmpC) has been emerged worldwide. The incidence of pAmpC resulted in increasing β‐lactamase production and conferred resistance to almost all β‐lactam antibiotics excluding carbapenems. The lack of standard method for pAmpC identification and classification exert a challenge in epidemiological surveillance and infection control practices.MethodsA robust, single tube multiplex PCR has been developed to classify six different pAmpC groups including CIT (CMY‐2 like, LAT and CFE), ECB (ACT, MIR), MOX & CMY‐1 like, DHA, ACC, and FOX. The developed method was optimized and validated by testing of sensitivity and specificity.ResultsDeveloped method can detect crude extracted DNA template at nano‐scale (2.5 ηg) and has high discriminatory power as compared to phenotypic and commercial genotypic method.ConclusionThe developed method can be utilized for tracking the changes of clinically important resistance patterns and further investigation of occurrence and distribution of plasmid‐mediated AmpC types.
Development of a bedside viable ultrasound protocol to quantify appendicular lean tissue mass
Authors: Paris Michael T. , Lafleur Benoit , Dubin Joel A. , Mourtzakis Marina 
Published: July 2017

AbstractBackgroundUltrasound is a non‐invasive and readily available tool that can be prospectively applied at the bedside to assess muscle mass in clinical settings. The four‐site protocol, which images two anatomical sites on each quadriceps, may be a viable bedside method, but its ability to predict musculature has not been compared against whole‐body reference methods. Our primary objectives were to (i) compare the four‐site protocol's ability to predict appendicular lean tissue mass from dual‐energy X‐ray absorptiometry; (ii) optimize the predictability of the four‐site protocol with additional anatomical muscle thicknesses and easily obtained covariates; and (iii) assess the ability of the optimized protocol to identify individuals with low lean tissue mass.MethodsThis observational cross‐sectional study recruited 96 university and community dwelling adults. Participants underwent ultrasound scans for assessment of muscle thickness and whole‐body dual‐energy X‐ray absorptiometry scans for assessment of appendicular lean tissue. Ultrasound protocols included (i) the nine‐site protocol, which images nine anterior and posterior muscle groups in supine and prone positions, and (ii) the four‐site protocol, which images two anterior sites on each quadriceps muscle group in a supine position.ResultsThe four‐site protocol was strongly associated (R2 = 0.72) with appendicular lean tissue mass, but Bland–Altman analysis displayed wide limits of agreement (−5.67, 5.67 kg). Incorporating the anterior upper arm muscle thickness, and covariates age and sex, alongside the four‐site protocol, improved the association (R2 = 0.91) with appendicular lean tissue and displayed narrower limits of agreement (−3.18, 3.18 kg). The optimized protocol demonstrated a strong ability to identify low lean tissue mass (area under the curve = 0.89).ConclusionsThe four‐site protocol can be improved with the addition of the anterior upper arm muscle thickness, sex, and age when predicting appendicular lean tissue mass. This optimized protocol can accurately identify low lean tissue mass, while still being easily applied at the bedside.
“The difference being a woman made” Untold Lives in personal and intellectual context
Authors: Rutherford Alexandra , Milar Katharine 
Published: July 2017

AbstractTo mark the 30th anniversary of the publication of Scarborough and Furumoto's classic work Untold Lives, and to honor the intellectual legacy of Elizabeth Scarborough (1935–2015), we introduce this special issue devoted to the histories of women, gender, and feminism in psychology. We provide a short biographical sketch of Elizabeth, highlighting her own marriage‐career dilemma, then contextualize the publication of Untold Lives within the historiography on women in psychology at that time. We conclude by discussing intersectionality as an analytic framework for the history of psychology as a way to extend and enrich this historiography.
ENSO influence on the interannual variability of the Red Sea convergence zone and associated rainfall
Authors: Dasari Hari Prasad , Langodan Sabique , Viswanadhapalli Yesubabu , Vadlamudi Brahmananda R. , Papadopoulos Vassilis P. , Hoteit Ibrahim 
Published: July 2017

ABSTRACTThe Red Sea convergence zone (RSCZ) is formed by opposite surface winds blowing from northwest to southeast directions at around 18°–19°N between October and January. A reverse‐oriented, low‐level monsoon trough at 850 hPa, known as the Red Sea trough (RST), transfers moisture from the southern Red Sea to RSCZ. The positions of the RSCZ and RST and the intensity of the RST have been identified as important factors in modulating weather and climatic conditions across the Middle East. Here, we investigate the influence of the El Niño southern oscillation (ENSO) on the interannual variability of RSCZ, RST, and regional rainfall during winter months. Our results indicate that El Niño (warm ENSO phase) favours a shift of the RSCZ to the north and a strengthening of the RST in the same direction. Conversely, during November and December of La Niña periods (cold ENSO phase), the RSCZ shift to the south and the RST strengthens in the same direction. During El Niño periods, southeasterly wind speeds increase (20–30%) over the southern Red Sea and northwesterly wind speeds decrease (10–15%) over the northern Red Sea. Noticeable increases in the number of rainy days and the intensity of rain events are observed during El Niño phases. These increases are associated with colder than normal air intrusion at lower levels from the north combined with warm air intrusion from the south over the RSCZ. Our analysis suggests that during El Niño winters, warmer sea surface temperatures and higher convective instability over the Red Sea favour local storms conditions and increase rainfall over the Red Sea and adjoining regions.
Graded replacement of maize grain with molassed sugar beet pulp modulated ruminal microbial community and fermentation profile in vitro
Authors: Münnich Matthias , Khol‐Parisini Annabella , Klevenhusen Fenja , Metzler‐Zebeli Barbara U , Zebeli Qendrim 
Published: July 2017

AbstractBACKGROUNDMolassed sugar beet pulp (Bp) is a viable alternative to grains in cattle nutrition for reducing human edible energy input. Yet little is known about the effects of high inclusion rates of Bp on rumen microbiota. This study used an in vitro approach and the quantitative polymerase chain reaction technique to establish the effects of a graded replacement of maize grain (MG) by Bp on the ruminal microbial community, fermentation profile and nutrient degradation.RESULTSSix different amounts of Bp (0–400 g kg−1), which replaced MG in the diet, were tested using the in vitro semi‐continuous rumen simulation technique. The increased inclusion of Bp resulted in greater dietary content and degradation of neutral detergent fibre (P < 0.01). Further, Bp feeding enhanced (P < 0.01) the abundance of genus Prevotella and shifted (P < 0.01) the short‐chain fatty acid patterns in favour of acetate and propionate and at the expense of butyrate. A total replacement of MG with Bp resulted in an increased daily methane production (P < 0.01).CONCLUSIONResults suggest positive effects of the replacement of MG by Bp especially in terms of stimulating ruminal acetate and propionate fermentation. However, high replacement rates of Bp resulted in lowered utilization of ammonia and higher ruminal methane production. © 2017 Society of Chemical Industry
Physical compatibility between wax esters and triglycerides in hybrid shortenings and margarines prepared in rice bran oil
Authors: Doan Chi Diem , Tavernier Iris , Danthine Sabine , Rimaux Tom , Dewettinck Koen 
Published: July 2017

AbstractBACKGROUNDWax esters contribute to the transformation of liquid oils into solid‐like oleogel systems, which can act as alternatives for trans‐ and/or saturated fats in food products. The use of solely waxes reduces the solid content, consistency and sensory quality in the final products. Therefore, a combination of sunflower wax and palm fat in rice bran oil was created to accomplish the hybrid low‐saturated shortenings and margarines with a compatible structure and lower amounts of saturated fats.RESULTSDuring cooling of the hybrid shortenings, sunflower wax crystallized first and acted as nucleation sites for the crystallisation of palm fat. At 5 °C, a mixture of different crystal morphologies (α, β', and β crystals) existed in the hybrid shortening. In margarine processing, the hybrid samples were subjected to a simultaneous cooling–emulsification, in which sunflower wax crystallised first at the interface and adsorbed onto the water droplets. Based on the hardness measurements, the maximum amount of palm fat replaceable by 1.0%wt sunflower wax was up to 40% in shortenings and 25% in margarines. A higher amount of sunflower wax (2.5%wt) reduced up to 40% of saturated fats in the hybrid emulsions.CONCLUSIONThe addition of 1.0%wt sunflower wax enhanced the solid content and network strength of hybrid palm‐based shortenings. Sunflower wax helped to stabilise the water droplets inside the wax‐based crystalline network without flocculation during shear‐cooling. This research provides fundamental insight into the structuring of hybrid systems containing waxes, which could be interesting for the production of low‐saturated fat products in the food industry. © 2017 Society of Chemical Industry