bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterned Liposome–Polymer Composite Coatings
Authors: Zhang Yan , Lynge Martin E. , Nielsen Morten B. , Schattling Philipp S. , Han Xiaojun , Städler Brigitte 
Published: May 2016

AbstractEngineered biointerfaces are crucial for many biomedical applications involving the interaction of (bio)materials with cells and tissue. Providing cues to support cell adhesion/proliferation in the form of biomolecules and/or by providing spatially controlled adhesive patches are important aspects. We demonstrate the assembly of composite films consisting of negatively charged liposomes (Ln), poly(dopamine) or cholesterol‐modified poly(methacrylic acid) (PMAc) capping layers and (poly(l‐lysine)/PMAc)x terminating multilayers. We show that hepatocytes adhere to the assembled composite coatings. Their association with fluorescent lipids from the film varies depending on the capping layer and cell adhesion time. This association was suggested to be an energy‐dependent process. Further, the incorporation of paclitaxel (TX) into Ln reduces the number of hepatocytes adhering to films without terminating multilayers. An exemplary composite coating is patterned, and the subsequent site‐selective adhesion of hepatocytes is shown. For the first time, composite coatings to be used for substrate‐mediated drug delivery with control over the positioning of the adhering cells are shown.
A Base‐Resistant ZnII‐Based Metal–Organic Framework: Synthesis, Structure, Postsynthetic Modification, and Gas Adsorption
Authors: He Tao , Zhang Yong‐Zheng , Wang Bin , Lv Xiu‐Liang , Xie Lin‐Hua , Li Jian‐Rong 
Published: May 2016

AbstractA ZnII‐based metal–organic framework (MOF), [Zn2(bdp‐CHO)2]⋅(DMF)(CH3CN)(H2O)2 (BUT‐31) is reported that was synthesized by the reaction between a newly designed aldehyde‐tagged polypyrazole ligand 2,5‐di(1H‐pyrazol‐4‐yl)benzaldehyde (H2bdp‐CHO) and a zinc salt. BUT‐31 has a unique pillared layered framework structure with 3D intersecting channels approximately 3.4–5.4 Å in size. Powder X‐ray diffraction and N2 adsorption experiments revealed that BUT‐31 is rigid and permanently porous with the Brunauer–Emmett–Teller surface area of 926 m2 g−1. Notably, this MOF tolerates boiling water and even highly basic aqueous solution (4 m sodium hydroxide), although dilute acid gradually decomposes its framework. Owing the permanent porosity and chemical stability of BUT‐31, covalent post‐modification of the free aldehyde group exposed on the pore surface was accomplished by treating the MOF in a concentrated ammonia solution (25 %) at near room temperature, giving rise to an imine‐functionalized analogue of BUT‐31. Gas adsorption results show that the aldehyde‐ and imine‐functionalized MOFs have high CO2 adsorption capacities, as well as CO2/N2 and CO2/CH4 adsorption selectivities.
Metal–Organic Frameworks M‐MOF‐74 and M‐MIL‐100: Comparison of Textural, Acidic, and Catalytic Properties
Authors: Palomino Cabello Carlos , Gómez‐Pozuelo Gema , Opanasenko Maksym , Nachtigall Petr , Čejka Jiří 
Published: May 2016

AbstractThe impact of the metal nature and framework type on the textural, acidic, and catalytic properties of M‐MOF‐74 (M=Co, Cu, Mg, Ni) and M‐MIL‐100 (M=Al, Cr, Sc, V) materials was evaluated. Both metal–organic framework (MOF) families showed 100 % selectivity to the tetrahydropyranyl ether for all alcohols (methanol, 1‐propanol, 1‐octanol, 2‐adamantanol, 1‐octadecanol) applied. Independently of the metal employed in the synthesis of M‐MOF‐74, the conversions were lower than those obtained with M‐MIL‐100. This result can be attributed to the combination of superior textural properties, accessibility, and strength of open metal sites in M‐MIL‐100 that improve the accessibility/diffusion of reactant and products. The variation of the size and shape of the alcohols on the activity and selectivity showed that the yield of tetrahydropyranyl ether decreased with increase of the alcohol size (methanol<1‐propanol<1‐octanol<2‐adamantanol<1‐octadecanol). The best catalytic results were achieved with V‐MIL‐100, and were even maintained after several cycles; this could be related to the superior polarizing power of V‐containing units, which enhanced the activation of 3,4‐dihydro‐2H‐pyran and, consequently, the yield of the target ether.
Titania Composites with 2 D Transition Metal Carbides as Photocatalysts for Hydrogen Production under Visible‐Light Irradiation
Authors: Wang Hui , Peng Rui , Hood Zachary D. , Naguib Michael , Adhikari Shiba P. , Wu Zili 
Published: May 2016

AbstractMXenes, a family of two‐dimensional transition‐metal carbides, were successfully demonstrated as co‐catalysts with rutile TiO2 for visible‐light‐induced solar hydrogen production from water splitting. The physicochemical properties of Ti3C2Tx MXene coupled with TiO2 were investigated by a variety of characterization techniques. The effect of the Ti3C2Tx loading on the photocatalytic performance of the TiO2/Ti3C2Tx composites was elucidated. With an optimized Ti3C2Tx content of 5 wt %, the TiO2/Ti3C2Tx composite shows a 400 % enhancement in the photocatalytic hydrogen evolution reaction compared with that of pure rutile TiO2. We also expanded our exploration to other MXenes (Nb2CTx and Ti2CTx) as co‐catalysts coupled with TiO2, and these materials also exhibited enhanced hydrogen production. These results manifest the generality of MXenes as effective co‐catalysts for solar hydrogen production.
Hierarchically‐Porous Carbon Derived from a Large‐Scale Iron‐based Organometallic Complex for Versatile Energy Storage
Authors: Fan Chao‐Ying , Li Huan‐Huan , Wang Hai‐Feng , Sun Hai‐Zhu , Wu Xing‐Long , Zhang Jing‐Ping 
Published: May 2016

AbstractInspired by the preparation of the hierarchically‐porous carbon (HPC) derived from metal organic frameworks (MOFs) for energy storage, in this work, a simple iron‐based metal– organic complex (MOC), which was simpler and cheaper compared with the MOF, was selected to achieve versatile energy storage. The intertwined 1 D nanospindles and enriched‐oxygen doping of the HPC was obtained after one‐step carbonization of the MOC. When employed in lithium‐ion batteries, the HPC exhibited reversible capacity of 778 mA h g−1 after 60 cycles at 50 mA g−1. Moreover, the HPC maintained a capacity of 188 mA h g−1 after 400 cycles at 100 mA g−1 as the anode material in a sodium‐ion battery. In addition, the HPC served as the cathode matrix for evaluation of a lithium–sulfur battery. The general preparation process of the HPC is commercial, which is responsible for the large‐scale production for its practical application.
Modeling and Simulations in Photoelectrochemical Water Oxidation: From Single Level to Multiscale Modeling
Authors: Zhang Xueqing , Bieberle‐Hütter Anja 
Published: May 2016

AbstractThis review summarizes recent developments, challenges, and strategies in the field of modeling and simulations of photoelectrochemical (PEC) water oxidation. We focus on water splitting by metal‐oxide semiconductors and discuss topics such as theoretical calculations of light absorption, band gap/band edge, charge transport, and electrochemical reactions at the electrode–electrolyte interface. In particular, we review the mechanisms of the oxygen evolution reaction, strategies to lower overpotential, and computational methods applied to PEC systems with particular focus on multiscale modeling. The current challenges in modeling PEC interfaces and their processes are summarized. At the end, we propose a new multiscale modeling approach to simulate the PEC interface under conditions most similar to those of experiments. This approach will contribute to identifying the limitations at PEC interfaces. Its generic nature allows its application to a number of electrochemical systems.
Increased expression of brother of the regulator of imprinted sites in peripheral blood neutrophils is associated with both benign and malignant breast lesions
Authors: El‐Sharkawy Nahla M. , Radwan Wafaa M. , Essa Enas S. , Kandeel Eman Z. , Abd El‐Fattah Eman K. , Kandil Samia H. , Kamel Azza M. 
Published: May 2016

BackgroundBORIS, a paralog of the multifunctional CCCTC‐binding factor (CTCF) gene is restricted to testis and normally not present in females. It is aberrantly activated in various human cancers including cancer breast. Using immunohistochemistry, western blot and/or RT‐PCR, significantly higher levels of BORIS expression were reported in the neutrophils of cancer breast patients. We hypothesized that Flow Cytometry might be a better technique for objective quantitative evaluation of BORIS in neutrophils and we wanted to investigate if BORIS would discriminate between benign and malignant breast lesions.MethodsThe study included 85 females; 52 breast cancer, 13 benign breast lesions and 20 age‐matched healthy controls. BORIS expression in the neutrophils was detected by Flow Cytometry.ResultsHigh level of BORIS was detected in all malignant (64.4 ± 16.6%) and benign cases (67 ± 12.3), mean florescent intensity ratio (MFIR) of 7.2 ± 4.1 and 7 ± 3.5, median 5.8 and 6.6%; and staining index (SI) 8.3 ± 3.9 and 8.2 ± 3.4, median 7.6 and 7.9 respectively vs.13.4 ± 11.5% MFI 1.8 ± 0.7, median1.6 and SI 2.6 ± 0.69, median 2.5 for the control. BORIS level was comparable in the malignant and benign group (P = 0.934) and significantly higher than control (P = 0.0001). There was no correlation between neutrophil BORIS expression and ER/PR status, HER‐2/neu expression or tumor stage or size.ConclusionsIncreased BORIS expression in peripheral blood neutrophils is associated with both benign and malignant breast lesions; apparently, increased proliferation of breast tissue is the determining factor. This excludes BORIS as a tumor marker but it does not jeopardize its value as a potential therapeutic target. © 2016 International Clinical Cytometry Society
Ecohydrological changes in semiarid ecosystems transformed from shrubland to buffelgrass savanna
Authors: Castellanos Alejandro E. , Celaya‐Michel Hernán , Rodríguez Julio C. , Wilcox Bradford P. 
Published: May 2016

AbstractIn arid and semiarid lands worldwide, vegetation cover is being transformed to savannas dominated by exotic grasses. However, the ecohydrological and biogeochemical changes associated with this process remain little understood. For more than 3 years, we studied soil moisture dynamics in natural semiarid shrubland patches and compared those with changes in an adjacent site that had been transformed to an exotic buffelgrass (Cenchrus ciliaris) savanna. We found that volumetric soil moisture was higher in patches with some kind of cover. For both tree and bare patches, volumetric soil moisture and plant‐available water in the 60‐ to 100‐cm depth interval were significantly lower in the savanna than in the natural site. In buffelgrass patches, volumetric soil moisture and plant‐available water were higher at almost all depths and in wet years and increased significantly during the summer monsoon season, suggesting rapid infiltration mechanisms under buffelgrass. During years with wet winters, these mechanisms also led to brief accumulations of water in the soil profile (0–200 cm). Such changes in soil profile water dynamics brought about adaptive responses in perennial plant species. The ability of species to change their patterns of soil water use in the profile may be an important mechanism enabling them to compete when novel tree–grass interactions are established by invasion of grasses. Our results provide new insights for understanding the changes caused by grass invasion in arid and semiarid lands, as well as how these changes may impact ecohydrological dynamics in global change scenarios. Copyright © 2016 John Wiley & Sons, Ltd.
Representing object categories by connections: Evidence from a mutivariate connectivity pattern classification approach
Authors: Wang Xiaosha , Fang Yuxing , Cui Zaixu , Xu Yangwen , He Yong , Guo Qihao , Bi Yanchao 
Published: May 2016

AbstractThe representation of object categories is a classical question in cognitive neuroscience and compelling evidence has identified specific brain regions showing preferential activation to categories of evolutionary significance. However, the potential contributions to category processing by tuning the connectivity patterns are largely unknown. Adopting a continuous multicategory paradigm, we obtained whole‐brain functional connectivity (FC) patterns of each of four categories (faces, scenes, animals and tools) in healthy human adults and applied multivariate connectivity pattern classification analyses. We found that the whole‐brain FC patterns made high‐accuracy predictions of which category was being viewed. The decoding was successful even after the contributions of regions showing classical category‐selective activations were excluded. We further identified the discriminative network for each category, which span way beyond the classical category‐selective regions. Together, these results reveal novel mechanisms about how categorical information is represented in large‐scale FC patterns, with general implications for the interactive nature of distributed brain areas underlying high‐level cognition. Hum Brain Mapp 37:3685–3697, 2016. © 2016 Wiley Periodicals, Inc.
Comparison between Focus Harmonic scalpel and other hemostatic techniques in open thyroidectomy: A systematic review and meta‐analysis
Authors: Cannizzaro Matteo Angelo , Borzì Laura , Lo Bianco Salvatore , Okatyeva Valeriya , Cavallaro Andrea , Buffone Antonino 
Published: May 2016

AbstractBackgroundThe purpose of this review was to compare the efficacy and surgical outcomes of total thyroidectomy between the Focus Harmonic scalpel (Ethicon, Cincinnati, OH) and other hemostatic procedures.MethodsAn extensive search was conducted using the PubMed and Cochrane databases from January 2008 to October 2014. Operating time, blood loss, pain, complications, and hospital stay were evaluated.ResultsWhen compared with conventional techniques or LigaSure Precise Vessel Sealing System (Medtronic, Minneapolis, MN), the use of the Focus Harmonic scalpel reduced operative time by 22,428 minutes and blood loss by 13,914 mL. Length of hospital stay was significantly shorter in the Focus Harmonic scalpel group with a mean reduction of 0.410 days.ConclusionAccording to our meta‐analysis, when comparing the Focus Harmonic scalpel versus conventional techniques, it seems evident that the use of this device in thyroid surgery is associated with a mean reduction in operating time, blood loss, and hospital stay, without any increase in pain and complications. There was no appreciable difference between the Focus Harmonic scalpel and the LigaSure Precise Vessel Sealing System. © 2016 Wiley Periodicals, Inc. Head Neck 38: First–1578, 2016
New Compounds from the Roots and Stems of Trigonostemon lii and Their Cytotoxic Activities
Authors: Liu Yong‐Qin , Di Ying‐Tong , Wang Yue‐Hu , Hao Xiao‐Jiang , Hu Xu‐Jia 
Published: May 2016

A new carboline alkaloid, Trifiline D (1) and a new degraded diterpenoid, Trigoxyphin X (4) were isolated from the roots and stems of Trigonostemon lii. Their structures were elucidated by extensive spectroscopic analyses including 1D‐ and 2D‐NMR techniques. Compound 1 exhibited weak inhibitory activity against MCF‐7, A‐549, MGC‐803, and COLO‐205 with IC50 values ranging from 27.4 to 35.4 μm.
Effect of edible coatings with essential oils on the quality of red raspberries over shelf‐life
Authors: Gomes Marcos de Souza , Cardoso Maria das Graças , Guimarães Ana Clara Garcia , Guerreiro Adriana Cavaco , Gago Custódia Maria Luís , Vilas Boas Eduardo Valério de Barros , Dias Cristina Maria Barrocas , Manhita Ana Cristina Cabaça , Faleiro Maria Leonor , Miguel Maria Graça Costa , Antunes Maria Dulce Carlos 
Published: May 2016

AbstractBACKGROUNDThe objective of the present work was to develop strategies for increasing the shelf‐life of red raspberries (Rubus idaeus L.), by preventing microorganism growth.RESULTSFruits coated with alginate plus lemon essential oil (0.2%) or orange essential oil (0.1%) after 15 days of storage had less red skin than the remaining samples. The less red color verified in these samples was also coincident with the lower concentration of anthocyanins at the end of the experiment as well as the lower capacity for scavenging ABTS free radicals or quenching singlet oxygen. Cyanidin and pelargonidin glucosides were found in raspberries fruits. The edible coatings supplemented with the essential oil of orange either at 0.1% or 0.2% were very efficient for controlling yeast and mold growth after 15 days of storage. To control the development of aerobic mesophilic bacteria the use of essential oil of lemon 0.2% and essential oil of orange 0.1% were the most efficient.CONCLUSIONThe application of the film improved post‐harvest quality of raspberry, since the addition of essential oils of citrus films promoted to the inhibitory effect of fungi and bacteria growth after 15 days of storage, without changing quality parameters. © 2016 Society of Chemical Industry
Echo time‐dependent quantitative susceptibility mapping contains information on tissue properties
Authors: Sood Surabhi , Urriola Javier , Reutens David , O’Brien Kieran , Bollmann Steffen , Barth Markus , Vegh Viktor 
Published: May 2016

PurposeMagnetic susceptibility is a physical property of matter that varies depending on chemical composition and abundance of different molecular species. Interest is growing in mapping of magnetic susceptibility in the human brain using magnetic resonance imaging techniques, but the influences affecting the mapped values are not fully understood.MethodsWe performed quantitative susceptibility mapping on 7 Tesla (T) multiple echo time gradient recalled echo data and evaluated the trend in 10 regions of the human brain. Temporal plots of susceptibility were performed in the caudate, pallidum, putamen, thalamus, insula, red nucleus, substantia nigra, internal capsule, corpus callosum, and fornix. We implemented an existing three compartment signal model and used optimization to fit the experimental result to assess the influences that could be responsible for our findings.ResultsThe temporal trend in susceptibility is different for different brain regions, and subsegmentation of specific regions suggests that differences are likely to be attributable to variations in tissue structure and composition. Using a signal model, we verified that a nonlinear temporal behavior in experimentally computed susceptibility within imaging voxels may be the result of the heterogeneous composition of tissue properties.ConclusionsDecomposition of voxel constituents into meaningful parameters may lead to informative measures that reflect changes in tissue microstructure. Magn Reson Med 77:1946–1958, 2017. © 2016 International Society for Magnetic Resonance in Medicine
Thermoplasticity and strain localization in transversely isotropic materials based on anisotropic critical state plasticity
Authors: Semnani Shabnam J. , White Joshua A. , Borja Ronaldo I. 
Published: May 2016

SummaryGeomaterials such as soils and rocks are inherently anisotropic and sensitive to temperature changes caused by various internal and external processes. They are also susceptible to strain localization in the form of shear bands when subjected to critical loads. We present a thermoplastic framework for modeling coupled thermomechanical response and for predicting the inception of a shear band in a transversely isotropic material using the general framework of critical state plasticity and the specific framework of an anisotropic modified Cam–Clay model. The formulation incorporates anisotropy in both elastic and plastic responses under the assumption of infinitesimal deformation. The model is first calibrated using experimental data from triaxial tests to demonstrate its capability in capturing anisotropy in the mechanical response. Subsequently, stress‐point simulations of strain localization are carried out under two different conditions, namely, isothermal localization and adiabatic localization. The adiabatic formulation investigates the effect of temperature on localization via thermomechanical coupling. Numerical simulations are presented to demonstrate the important role of anisotropy, hardening, and thermal softening on strain localization inception and orientation. Copyright © 2016 John Wiley & Sons, Ltd.
Global output feedback stabilization for a class of nonlinear systems with quantized input and output
Authors: Li Guangqi , Lin Yan , Zhang Xu 
Published: May 2016

SummaryIn this paper, we aim at addressing the problem of global output feedback stabilization for a class of uncertain nonlinear systems with quantized input and output. The nonlinear functions of the system are assumed to satisfy high‐order growth condition on the unmeasurable states. Based on the homogeneous domination approach and sector bound approach, a homogeneous quantized controller computed from quantized output is constructed, and a guideline is derived to select the parameters of the quantizers. Further, it is proved that, with the proposed scheme, the closed‐loop system is globally asymptotically stable. Copyright © 2016 John Wiley & Sons, Ltd.
Preterm delivery after fetoscopic laser surgery for twin–twin transfusion syndrome: etiology and risk factors
Authors: Malshe A. , Snowise S. , Mann L. K. , Boring N. , Johnson A. , Bebbington M. W. , Moise K. J. , Papanna R. 
Published: May 2016

ABSTRACTObjectivePreterm delivery after fetoscopic laser surgery (FLS) for twin–twin transfusion syndrome (TTTS) is a major complication. The causative factors leading to preterm delivery continue to be elusive and a better understanding of the risk factors could reduce complications. The objective of this study was to determine the etiology of preterm delivery after FLS for TTTS and its associated risk factors.MethodsThis was a secondary analysis of a prospective study of 203 patients with TTTS who underwent FLS at a single center between September 2011 and December 2014. Preoperative, operative, postoperative, delivery and neonatal data were reviewed. Preterm delivery was categorized according to etiology into three groups: spontaneous (SPT), indicated (IND) and elective (ELC). Comparisons between groups were performed by ANOVA. Kaplan–Meier survival analysis was performed to compare the procedure‐to‐delivery interval between groups. To identify risk factors for preterm delivery, logistic regression, with calculation of relative risks (RR), was performed, with P < 0.05 considered statistically significant.ResultsMean gestational age at time of FLS was 20.6 ± 2.4 weeks and mean gestational age at delivery was 30.9 ± 4.7 weeks. Iatrogenic preterm prelabor rupture of membranes (iPPROM) occurred in 39% of cases. SPT preterm delivery occurred in 97 (48%) patients, IND preterm delivery in 65 (32%) and ELC preterm delivery in 41 (20%). In the IND group, 30 (46%) patients delivered for fetal indications, 31 (48%) for maternal indications and four (6%) for combined fetal and maternal indications. The overall chorioamnionitis rate was 6.4%; of these, nine (9%) were in the SPT group and four (6%) were in the IND group, with no case occurring in the ELC group. There was a significant difference in procedure‐to‐delivery interval between groups (P < 0.0001). Using variables from the ELC group as a baseline, significant risk factors for SPT preterm delivery were iPPROM (RR, 16.2 (95% CI, 4.5–57.7)), preoperative cervical length (RR, 0.96 (95% CI, 0.92–0.998)) and number of anastomoses (RR, 1.14 (95% CI, 1.02–1.27)). Significant risk factors for IND preterm delivery were iPPROM (RR, 9.6 (95% CI, 2.6–35.0)) and number of ablated anastomoses (RR, 1.13 (95% CI, 1.02–1.30)).ConclusioniPPROM and an increased number of ablated placental anastomoses were associated independently with SPT and IND preterm deliveries. A shorter preoperative cervical length was associated with SPT preterm delivery. Strategies to prevent iPPROM and for management of cervical length shortening are needed urgently in these pregnancies. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.