bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sensitive Electrochemical Sensing Properties for Cyanide Detection Using Polyaniline/Cu-Vanadate Nanobelt-modified Electrode
Authors: Zhang Yong , Cong Qianmin , Feng Chenxu , Cai Zhengyu , Pei Lizhai 
Published: October 2024

Background:
Cyanide is a toxic anion and may be discarded into the water environment,
which is a serious threat to human beings and the environment. Hence, it is essential to explore a
facile, sensitive method for cyanide detection. Polyaniline/Cu vanadate nanobelts serve as electrode
materials for sensitive cyanide determination.

Methods:
Polyaniline/Cu vanadate nanobelts were obtained by a simple route using polyaniline, Cu
vanadate nanobelts. The polyaniline/Cu vanadate nanobelts were measured via electron microscopy,
diffraction, infrared spectrum, and electrochemical methods.

Results:
Amorphous polyaniline nanoparticles with a particle size of about 100 nm were attached
firmly to the surface of Cu vanadate nanobelts. Electrochemical sensing properties for cyanide detection
were analyzed using a cyclic voltammetry technique using the nanobelts-modified electrode.
The cyclic voltammograms (CV) peaks centered at +0.64 V and +0.54 V were observed using the
polyaniline/Cu vanadate nanobelts in 0.1 M KCl solution with 2 mM cyanide. The proposed composite
nanobelt-modified electrode possessed the detection range and detection limit of 0.001-2 mM
and 0.22 μM, respectively.

Conclusion:
Polyaniline greatly enhances the electro-catalytic performance of the Cu vanadate
nanobelt-modified electrode for cyanide detection.
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Ulcer Healing in Diabetes Mellitus Type 2 Mice
Authors: Feng Wenpo , Feng Chenxi , Wang Binbin , Lv Mengqi , LI Xicong , Jing Aihua , Qiu Yuanhao , Gao Huashan , Liang Gaofeng 
Published: October 2024

Background:
With the passage of time, the incidence rate of diabetes continues to rise. As a
common and serious complication of diabetes, the economic burden of diabetes ulcers is also increasing.
However, there is currently no unified clinical treatment strategy for its repair and research, and the treatment
effect is not satisfactory. Exosomes derived from MSCs play a crucial role in improving diseases.

Methods:
This study used the explant culture method to isolate human umbilical cord mesenchymal
stem cells (hucMSCs) from Wharton’s jelly, which were identified by flow cytometry and differentiation
potential and evaluated tumorigenic potential. The supernatant of P3-P5 cell culture medium
was collected and high-concentration human umbilical cord mesenchymal stem cell exosomes
(hucMSCs-Exos) were isolated through ultracentrifugation. Qualitatively identified were finished by
transmission electron microscopy (TEM), nanosight tracking analysis (NTA) and Western blot
(WB). CCK-8 assay and cell scratch experiment were used to evaluate the effects of hucMSCs-Exos
on proliferation and migration ability of cells; chicken embryo chorioallantoic membrane experiment
(CAM) was used to evaluate the angiogenic effect of hucMSCs-Exos. In order to study the effect of
hucMSCs-Exos on diabetes wound healing, the diabetes mouse model was constructed by a high-fat
feeding and a low-dose STZ injection. Fasting blood glucose and blood lipids were measured and
oral glucose tolerance test (OGTT) was conducted; HucMSCs-Exos were subcutaneously injected
into the T2DM wound model mice which were established by a high-fat diet and by a low-dose
streptozotocin (STZ), and the wound healing was evaluations.

Results:
Cells were isolated by explant culture method, and flow cytometry analyses showed that
these isolated cells were positive for cells markers CD29, CD90, and CD105, while negative for
CD34 and CD45; moreover, these cells could be induced to osteoblasts, adipocytes, and islet-like
cells. The tumorigenic experiments showed that these cells have no tumorigenicity. HucMSCs-Exos,
separated by ultracentrifugation, displayed spherical or ellipsoidal vesicles with a diameter of around
120nm, positive for CD9, CD63, and CD81. And they could promote cell proliferation and migration,
as well as promote vascular growth (p < 0.01). In vivo experiments showed that hucMSCs-Exos
had a promoting effect on wound repair in diabetes mellitus type 2 (T2DM) mice (p < 0.01).

Conclusion:
This study provides a new scheme for the treatment of T2DM ulcer.
Obesity and COVID-19 Severity: Dissecting the Combined Relationship, Mechanisms, Diagnostic Obstacles, Management Approaches, and Treatment Plans
Authors: Kumari Risha , Negi Poonam , Agarwal Shweta 
Published: October 2024

Background:
This review delves into the intricate relationship between obesity and
COVID-19 severity, uncovering mechanistic insights such as immunological dysregulation, inflammation,
and metabolic complexities. It addresses challenges in diagnosis and treatment, advocating
for tailored approaches. Emphasis is placed on proper management and customized dietary interventions
to mitigate severity.

Methodology:
Scientific data related to obesity and COVID-19 was obtained from data bases like
PubMed, Scopus, google, and google scholar. The search words employed for the data search were
“Mechanisms linking obesity and COVID-19”, “Inflammatory milieu,” “Immune dysregulation”,
“Impact of obesity on COVID-19 Severity”, and “Dual relationship between obesity and COVID-
19”. Only relevant data related to the intricate relationship between obesity and COVID-19 severity
and its management was included.

Results:
This paper explores the multifaceted mechanisms linking obesity to increased COVID-19
severity, including immunological dysregulation, inflammatory responses, and metabolic comorbidities.
This review highlights complex problems that arise in the diagnosis and treatment of obese people
with COVID-19. These problems range from precise diagnosis to individualized treatment plans.
Management approaches for obese individuals with COVID-19 encompass lifestyle interventions,
pharmacotherapy, and dietary considerations, each tailored to mitigate risks and improve outcomes.
Additionally, treatment plans integrating multidisciplinary care, including personalized respiratory
support, antiviral therapy, and thromboprophylaxis, are proposed to address the unique needs of
obese patients battling COVID-19.

Conclusion:
The abstract underscores the complexity of this interaction, emphasizing the need for
comprehensive information to guide clinical care and future research effectively.
Feasibility and Engagement of a Mobile App Preparation Program (Kwit) for Smoking Cessation in an Ecological Context: Quantitative Study
Authors: Bustamante Perez Luz Adriana , Romo Lucia , Zerhouni Oulmann 
Published: October 2024

Background
Mobile health apps can facilitate access to effective treatment and therapeutic information services. However, the real-world effectiveness of mobile apps for smoking cessation and their potential impact in everyday settings remain unclear.

Objective
In an ecological context, this study aimed to estimate the engagement rate of a mobile app–based smoking cessation preparation program and its potential impact on users’ willingness, ability, and readiness to quit smoking.

Methods
A total of 2331 “organic users” (ie, users who discover and install a mobile app on their own, without any prompts) chose 1 of 2 program versions of the mobile app (Kwit): the basic version or the premium version. Both versions were identical in design, with 4 more evidence-based content items and strategies in the premium version. Outcomes were analyzed based on automated data registered in the app (engagement rate, motivation to quit, motivation type, motivation levels, and satisfaction level). Mann-Whitney and χ2 tests were used to compare the results of both groups.

Results
As expected, in the ecological context, a high dropout rate was observed at different moments. A significant difference was observed between the 2 versions (n=2331; χ21=5.4; P=.02), with a proportionally higher engagement rate in the premium version (premium=4.7% vs basic=2%). Likewise, differences were also observed between the 2 groups in terms of reasons to quit (n=2331; χ24=19; P≤.001; V=0.08), motivation type (n=2331; χ27=14.7; P=.04), and motivation level. Users of the app’s premium version more frequently reported “well-being” (23.3% vs 17.9%) and “planning a pregnancy” (7.4% vs 4.4%) as their primary reasons for quitting smoking compared to those with the basic version. Moreover, they reported being more likely to be driven in the smoking cessation process by intrinsic motivation (premium=28% vs basic=20.4%), as well as feeling significantly more willing (z score=156,055; P≤.001; Cohen d=0.15), able (z score=172,905; P=.04; Cohen d=0.09), and ready (z score=166,390; P=.005; Cohen d=0.12) to stop smoking than users who had the basic version before completion of the preparation program. Among participants who finished each version of the program (premium: 9/189, 4.8%; basic: 47/2142, 2.19%), significant improvements in motivation levels were observed in both groups, although in different areas for each group (willingness levels for the premium group and ability for the basic group).

Conclusions
These results suggest that even in ecological contexts where engagement rates are meager, the Kwit preparation program can address ambivalence by increasing willingness to change, self-confidence, and readiness to quit among its users, especially those who feel less able to do so. Further development and evaluations are needed to better understand determinants for regular mobile health apps.
A Collection of Components to Design Clinical Dashboards Incorporating Patient-Reported Outcome Measures: Qualitative Study
Authors: Bischof Anja Yvonne , Kuklinski David , Salvi Irene , Walker Carla , Vogel Justus , Geissler Alexander 
Published: October 2024

Background
A clinical dashboard is a data-driven clinical decision support tool visualizing multiple key performance indicators in a single report while minimizing time and effort for data gathering. Studies have shown that including patient-reported outcome measures (PROMs) in clinical dashboards supports the clinician’s understanding of how treatments impact patients’ health status, helps identify changes in health-related quality of life at an early stage, and strengthens patient-physician communication.

Objective
This study aims to determine design components for clinical dashboards incorporating PROMs to inform software producers and users (ie, physicians).

Methods
We conducted interviews with software producers and users to test preselected design components. Furthermore, the interviews allowed us to derive additional components that are not outlined in existing literature. Finally, we used inductive and deductive coding to derive a guide on which design components need to be considered when building a clinical dashboard incorporating PROMs.

Results
A total of 25 design components were identified, of which 16 were already surfaced during the literature search. Furthermore, 9 additional components were derived inductively during our interviews. The design components are clustered in a generic dashboard, PROM-related, adjacent information, and requirements for adoption components. Both software producers and users agreed on the primary purpose of a clinical dashboard incorporating PROMs to enhance patient communication in outpatient settings. Dashboard benefits include enhanced data visualization and improved workflow efficiency, while interoperability and data collection were named as adoption challenges. Consistency in dashboard design components is preferred across different episodes of care, with adaptations only for disease-specific PROMs.

Conclusions
Clinical dashboards have the potential to facilitate informed treatment decisions if certain design components are followed. This study establishes a comprehensive framework of design components to guide the development of effective clinical dashboards incorporating PROMs in health care practice.
Clinical Use of Mental Health Digital Therapeutics in a Large Health Care Delivery System: Retrospective Patient Cohort Study and Provider Survey
Authors: Ridout Samuel J , Ridout Kathryn K , Lin Teresa Y , Campbell Cynthia I 
Published: October 2024

Abstract

Background
While the number of digital therapeutics (DTx) has proliferated, there is little real-world research on the characteristics of providers recommending DTx, their recommendation behaviors, or the characteristics of patients receiving recommendations in the clinical setting.

Objective
The aim of this study was to characterize the clinical and demographic characteristics of patients receiving DTx recommendations and describe provider characteristics and behaviors regarding DTx.

Methods
This retrospective cohort study used electronic health record data from a large, integrated health care delivery system. Demographic and clinical characteristics of adult patients recommended versus not recommended DTx by a mental health provider between May 2020 and December 2021 were examined. A cross-sectional survey of mental health providers providing these recommendations was conducted in December 2022 to assess the characteristics of providers and recommendation behaviors related to DTx. Parametric and nonparametric tests were used to examine statistical significance between groups.

Results
Of 335,250 patients with a mental health appointment, 53,546 (16%) received a DTx recommendation. Patients recommended to DTx were younger, were of Asian or Hispanic race or ethnicity, were female, were without medical comorbidities, and had commercial insurance compared to those without a DTx recommendation (P<.001). More patients receiving a DTx recommendation had anxiety or adjustment disorder diagnoses, but less had depression, bipolar, or psychotic disorder diagnoses (P<.001) versus matched controls not recommended to DTx. Overall, depression and anxiety symptom scores were lower in patients recommended to DTx compared to matched controls not receiving a recommendation, although female patients had a higher proportion of severe depression and anxiety scores compared to male patients. Provider survey results indicated a higher proportion of nonprescribers recommended DTx to patients compared to prescribers (P=.008). Of all providers, 29.4% (45/153) reported using the suggested internal electronic health record–based tools (eg, smart text) to recommend DTx, and of providers recommending DTx resources to patients, 64.1% (98/153) reported they follow up with patients to inquire on DTx benefits. Only 38.4% (58/151) of respondents report recommending specific DTx modules, and of those, 58.6% (34/58) report following up on the impact of these specific modules.

Conclusions
DTx use in mental health was modest and varied by patient and provider characteristics. Providers do not appear to actively engage with these tools and integrate them into treatment plans. Providers, while expressing interest in potential benefits from DTx, may view DTx as a passive strategy to augment traditional treatment for select patients.
Morphology of Bacteria and Fungi From The Fermentation of Asam Drien as a Local Food Ingredient of West Aceh
Authors: Zuraidah Zuraidah , Nursanty Risa , Rahmi Rahmi 
Published: October 2024

A typical food ingredient of the Aceh region, especially the western and southern, is Asam drien (language from the West Aceh region). Asam drien is made from durian fruit meat, usually due to the abundance of durian fruit, or because the durian fruit is of poor quality such as the taste of the bland fruit meat, then most of the people utilize the durian fruit into Asam drien which can be used as a seasoning for cooking. The purpose of this study was to identify the morphological characteristics of bacterial and fungal colonies in Asam drien processing, this study used a qualitative descriptive method for colony characteristics, and biochemical tests. The results of research on bacteria and fungi in Asam drien found 14 colonies from the entire fermentation both at home and in the laboratory, namely irregular and diffuse, elongated, round, and threaded shapes; colony color characteristics obtained only one color, namely cream color; characteristics of colony edges there are 5, namely: wavy, squiggly, smooth, serrated, and threadbare. Colony elevation characteristics obtained 2 forms, namely flat and raised. There are 2 types of colony surface characteristics, namely rough and smooth shiny. Then reisolated on selective media DeMan Rogosa Sharpe Agar (MRS Agar) for lactic acid bacteria. The results of observations found 11 colonies from the entire fermentation each consisting of 2 types of isolates Ka and Kb which are Gram-positive bacteria bacillus and coccus cell forms. As well as fungi that grow on Asam drien, namely the genus Rhizopus and the type of yeast found from the genus Saccharomyces. The catalase test on Asam drien bacteria is positive, has proteolytic, amylolytic, and cellulolytic potential, but is not able to hydrolyze fat and alcohol.
الحرب الروسية الأوكرانية وتداعياتها على الأمن الغذائي العالمي
Authors: د. ضفاف كامل كاظم الخفاجي  
Published: October 2024

كشفت الحرب الروسية – الاوكرانية عن العلاقة الهشة بين الأمن الغذائي ونظام الغذاء العالمي، وعرضته للخطر، للأهمية التي تحتلها أوكرانيا بالنسبة للعالم لكونها المورد الرئيس للأغذية ، وذلك لان قطاع الزراعة والانشطة المتعلقة بها تساهم بشكل كبير في اقتصاد العالم ، وتشكل كل من روسيا واوكرانيا معا 25% من صادرات العالم من الحبوب ، وان الحرب بين البلدين افقدت اوكرانيا السيطرة في التصدير الغذاء مما تسبب بإضرار جسيمة في تجارة وانتاج الغذاء في العالم، فضلا عن قيام البلدان في المبالغة في زيادة حجم مخزونها من المنتجات الغذائية تحسبا للتقلبات المحتملة في الانتاج والتصدير وارتفاع الاسعار و ان الازمة بين روسيا واوكرانيا لها تأثير سلبي على الامن الغذائي العالمي وذلك نتيجة النقص الذي يحصل في امدادت الغذاء، فأثرت الحرب بشكل سلبي على الامن الغذائي بسبب النقص في الامدادات الغذائية في اغلب دول العالم.
دور الولايات المتحدة الامريكية في الازمة الأوكرانية (مؤسسة الرئاسة انموذجا)
Authors: د. عمار طه لطيف الدليمي  
Published: October 2024

تعتبر الولايات المتحدة الامريكية من أبرز القوى المؤثرة التي فوجئت بالحرب الاوكرانية الروسية ، إلا أن الأداء الأمريكي المصاحب للحرب يؤشر بما لا يدع مجالاً للشك أن شيئاً ما أصاب ماكينة القرار الامريكي وجعلها تسير ببطء في بعض الأحيان وبتعثر في أحيان أخرى. إلا أن طبيعة منظومة القرار في مجلس الأمن القومي الامريكي المستندة على خطط وآليات تحليل وتقدير وبدائل، والمعتمدة على فريق كبير من الخبراء والمحللين وموارد معلومات هائلة تخفف من وطأة التباطؤ والتعثر حتى يكاد المتابع من الخارج لا يلمس شيئاً كبيراً يذكر إلا إذا فهم طبيعة عمل مجلس الأمن القومي الامريكي وصلاحياته وامكانيته التنفيذية. ومما تقدم يظهر من هذه العينة القليلة من التعثرات (التي ذكرناها في فقرة التقييم السابقة) أن الإدارة الامريكية لم تستطع إدارة أزمة أوكرانيا جيداً وذلك بسبب وجود نقاط ضعف بشان القرار الاستراتيجي الامريكي في أوروبا والعالم وأن كل ما تم عمله في مجلس الأمن القومي من محاكاة وطرح بدائل وفرضيات كانت اختبارات نظرية بشكل كبير وعندما اصطدمت بالواقع بدأت الأخطاء تظهر وتتراكم. هل يشكل الحرب على أوكرانيا بداية لمتغيرات كبيرة تخص التوازنات الكبرى على الساحة الدولية، وتغييرات في سياسات الدول العظمى، باتجاه تشكيل تحالفات وتقاربات جديدة؟
(الولايات المتحدة الامريكية ، روسيا الاتحادية ، اوكرانيا ، الساحة الدولية ، سياسات الدول ، الدول)
المحددات الاجتماعية للرأي العام في العراق
Authors: الباحث علي حازم مهدي  , ا.د قاسم علوان سعيد  
Published: October 2024

الرأي العام كظاهرة اجتماعية لها ابعاد مختلفة فهي تنبع من صلب الظرف والواقع والمكان، وكل تلك الاوجه ذات صلة بالمجتمع ولصيقة به وتلقي بتأثيراتها على المواطن الذي هو في الاساس يعتبر الجهة التي يتبلور الرأي العام عندها وينطلق منها، وكما هو معروف ان لكل مجتمع ومنها المجتمع العراقي خصوصيات ذات صلة بتركيبته الديموغرافية وتكوينات تقسيماته المجتمعية ومستوى ثقافته والتي بحكم ارتباط المواطن بذلك التركيب والنسق المجتمعي بنيويا ومعنويا، فأنه لابد بشكل او باخر ان يؤثر ذلك الارتباط ومدى ضعفه وقوته في مخرجات وطبيعة الراي العام الذي يحمله المواطن العراقي ، فكان بطبيعة الحال ان ترسخ عادات وقيم في المجتمع وما يقويها من مؤسسات دينية وعشائرية فضلا عن التركيبة المجتمعية للمجتمع العراقي المعروف بتعقد تركيبته ذات التفرعات الاثنية والمذهبية والدينية والقومية والتي اثرت على نوع ومستوى الثقافة للمواطن العراقي والتي انعكست على توجهات المواطن واصبح لها الاثر في سلوكياته وبالتالي الراي العام الذي يحمله الفرد .
THE ARCHITECTURE OF THE RAILWAY STATIONS OF THE URALS 1920-1950 YEARS
Authors: Каптиков А.Ю. 
Published: October 2024

Статья завершает серию авторских публикаций, посвященных архитектурным объектам железных дорог Урала, сооруженным в 1920-1950-е годы. Автор анализирует их художественно-стилевую эволюцию, особенности объемного построения и фасадного оформления, включая ордер. На уральских железных дорогах представлены в чрезвычайно интересном применении к утилитарным объектам различные исторические стили, а также своеобразные варианты модерна и конструктивизма. ©Каптиков А. Ю., 2017
The paper completes the series of author’s publications devoted to architectural objects of Railways of the Urals, built in the 1920-1950-ies, the Author analyzes their stylistic evolution, the characteristics of bulk building and fasade design, including the warrant. On the Ural Railways are presented in a very interesting applied to utilitarian objects of various historical styles as well as original versions of art Nouveau and constructivism.
CRITERIA FOR ASSESSING CULTURAL HERITAGE SITES: CULTURAL AND HISTORICAL ASPECT AND LEGAL DECISION
Authors: КУРАШОВ Ю.Ю. 
Published: October 2024

На основе действующих правовых актов и существующих методик оценки ценности объектов культурного наследия автор предлагает полученные в результате исследования критерии ценности для оценки объекта культурного наследия экспертом государственной историко-культурной экспертизы. ©Курашов Ю. Ю., 2017
On the basis of existing legal acts and the existing methods of valuation of cultural heritage, the author offers obtained in the result of the study, the criteria values for evaluating a cultural heritage expert of the state historical-cultural expertise.
TYPES OF RESIDENTIAL DEVELOPMENT. THE MODERN STATE
Authors: КАЛАБИН А.В. 
Published: October 2024

В статье анализируется современный опыт массового жилищного строительства, прослеживаются трансформации различных видов жилой застройки, отмечаются их преимущества и недостатки. Отдельно анализируются предложения Правительства Москвы по формированию кварталов в зонах реновации столицы, изменения в нормативной документации. Анализируются перспективные разработки молодых архитекторов. ©Калабин А. В., 2017
This article analyzes the contemporary experience of mass housing, traced the transformation of different types of residential development are their advantages and disadvantages. Separately analyzed the proposal by the Government of Moscow on the formation of districts in the capital renovation zones, changes in the normative documentation. Examines promising young architects.
TRADITIONAL CRAFTS IN DETAILS OF INTERIORS AND EXTERIORS OF CONTEMPORARY BRITISH PUBLIC BUILDINGS
Authors: МАРЬЯСОВА М.К. 
Published: October 2024

В статье предложено видение использования региональных ремесел и ресурсов для оформления британских ансамблей и парламента. Раскрыта связь бренда и национальной культуры, дается представление о продуктах, являющихся специфичными для Ирландии, Шотландии и Уэльса. Представлена информация об объектах современного искусства, отображающих связь с кельтской культурой. ©Марьясова М. К., 2017
In following article we offer our observation at the usage of regional crafts and resources for the decoration of British assemblies and parliament. Аlso the connection between brend and national culture is shown, and the description about products, specific for Ireland, Scotland and Wales, as well as the information about objects of contemporary art in their connection with celtic culture are given.