bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Paris Peoples' Tribunal and the Istanbul Trials: Archives of the Armenian Genocide
Authors: SIMM GABRIELLE 
Published: February 2016

AbstractThe decisions of international courts and tribunals affect how we read history. Alternative tribunals, such as peoples’ tribunals, attempt to write alternative histories to counter the official versions. This article locates controversies over the Armenian genocide in debates about the relationship between history and international law. It considers ways of reading archives and the role of archives in informing those debates. It compares the Istanbul war crimes trials held in 1919–1920 before the Ottoman Military Tribunals with the Paris session of the Permanent Peoples’ Tribunal held in 1984 that dealt with questions of history and memory through the juridical format of a hearing. A century after the events of 1915, the contested historiography of the Armenian genocide influences how international lawyers and historians seek to pass judgment on the past.
On Kant’s Duty to Speak the Truth
Authors: Mertens Thomas 
Published: February 2016

AbstractIn ‘On the Supposed Right to Lie from Philanthropy’, Kant defends a position that cannot be salvaged. The essay is nonetheless important because it helps us understand his philosophy of law and, more specifically, his interpretation of the social contract. Kant considers truthfulness a strict legal duty because it is the necessary condition for the juridical state. As attested by Kant’s rejection of Beccaria’s arguments against the death penalty, not even the right to life has such strict unconditional status. Within the juridical state, established by the social contract, the (single) innate right to freedom is transformed into a bundle of merely positive rights, including the right to life. Understanding the reason for the rejection of ‘the right to lie from philanthropy’ thus helps us understand the, in a sense, ‘positivist’ character of Kant’s legal philosophy. In conclusion, some suggestions are made to bring his position closer to our common moral understanding.
The Public Form of Law: Kant on the Second-Personal Constitution of Freedom
Authors: Zylberman Ariel 
Published: February 2016

AbstractThe two standard interpretations of Kant’s view of the relationship between external freedom and public law make one of the terms a means for the production of the other: either public law is justified as a means to external freedom, or external freedom is justified as a means for producing a system of public law. This article defends an alternative, constitutive interpretation: public law is justified because it is partly constitutive of external freedom. The constitutive view requires conceiving of external freedom in a novel, second-personal way, that is, as an irreducibly relational norm.
Mental health and psychosocial wellbeing of Syrians affected by armed conflict
Authors: Hassan G. , Ventevogel P. , Jefee-Bahloul H. , Barkil-Oteo A. , Kirmayer L. J. 
Published: February 2016

Aims.This paper is based on a report commissioned by the United Nations High Commissioner for Refugees, which aims to provide information on cultural aspects of mental health and psychosocial wellbeing relevant to care and support for Syrians affected by the crisis. This paper aims to inform mental health and psychosocial support (MHPSS) staff of the mental health and psychosocial wellbeing issues facing Syrians who are internally displaced and Syrian refugees.Methods.We conducted a systematic literature search designed to capture clinical, social science and general literature examining the mental health of the Syrian population. The main medical, psychological and social sciences databases (e.g. Medline, PubMed, PsycInfo) were searched (until July 2015) in Arabic, English and French language sources. This search was supplemented with web-based searches in Arabic, English and French media, and in assessment reports and evaluations, by nongovernmental organisations, intergovernmental organisations and agencies of the United Nations. This search strategy should not be taken as a comprehensive review of all issues related to MHPSS of Syrians as some unpublished reports and evaluations were not reviewed.Results.Conflict affected Syrians may experience a wide range of mental health problems including (1) exacerbations of pre-existing mental disorders; (2) new problems caused by conflict related violence, displacement and multiple losses; as well as (3) issues related to adaptation to the post-emergency context, for example living conditions in the countries of refuge. Some populations are particularly vulnerable such as men and women survivors of sexual or gender based violence, children who have experienced violence and exploitation and Syrians who are lesbian, gay, bisexual, transgender or intersex. Several factors influence access to MHPSS services including language barriers, stigma associated with seeking mental health care and the power dynamics of the helping relationship. Trust and collaboration can be maximised by ensuring a culturally safe environment, respectful of diversity and based on mutual respect, in which the perspectives of clients and their families can be carefully explored.Conclusions.Sociocultural knowledge and cultural competency can improve the design and delivery of interventions to promote mental health and psychosocial wellbeing of Syrians affected by armed conflict and displacement, both within Syria and in countries hosting refugees from Syria.
Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis
Authors: Jinesh GG , Molina JR , Huang L , Laing NM , Mills GB , Bar-Eli M , Kamat AM 
Published: February 2016

AbstractApoptosis culminates in secondary necrosis due to lack of ATP. Cancer stem cells form spheres after apoptosis by evoking the blebbishield emergency program. Hence, determining how blebbishields avoid secondary necrosis is crucial. Here we demonstrate that N-Myc and VEGFR2 control transformation from blebbishields, during which oligomers of K-Ras, p27, BAD, Bax, and Bak boost glycolysis to avoid secondary necrosis. Non-apoptotic cancer cells also utilize oligomers to boost glycolysis, which differentiates the glycolytic function of oligomers from their apoptotic action. Smac mimetic in combination with TNF-α or TRAIL but not in combination with FasL abrogates transformation from blebbishields by inducing secondary necrosis. Thus blebbishield-mediated transformation is dependent on glycolysis, and Smac mimetics represent potential candidates to abrogate the blebbishield emergency program.
The puzzling Venusian polar atmospheric structure reproduced by a general circulation model
Authors: Ando Hiroki , Sugimoto Norihiko , Takagi Masahiro , Kashimura Hiroki , Imamura Takeshi , Matsuda Yoshihisa 
Published: February 2016

AbstractUnlike the polar vortices observed in the Earth, Mars and Titan atmospheres, the observed Venus polar vortex is warmer than the midlatitudes at cloud-top levels (∼65 km). This warm polar vortex is zonally surrounded by a cold latitude band located at ∼60° latitude, which is a unique feature called ‘cold collar’ in the Venus atmosphere. Although these structures have been observed in numerous previous observations, the formation mechanism is still unknown. Here we perform numerical simulations of the Venus atmospheric circulation using a general circulation model, and succeed in reproducing these puzzling features in close agreement with the observations. The cold collar and warm polar region are attributed to the residual mean meridional circulation enhanced by the thermal tide. The present results strongly suggest that the thermal tide is crucial for the structure of the Venus upper polar atmosphere at and above cloud levels.
Observing mesoscale eddy effects on mode-water subduction and transport in the North Pacific
Authors: Xu Lixiao , Li Peiliang , Xie Shang-Ping , Liu Qinyu , Liu Cong , Gao Wendian 
Published: February 2016

AbstractWhile modelling studies suggest that mesoscale eddies strengthen the subduction of mode waters, this eddy effect has never been observed in the field. Here we report results from a field campaign from March 2014 that captured the eddy effects on mode-water subduction south of the Kuroshio Extension east of Japan. The experiment deployed 17 Argo floats in an anticyclonic eddy (AC) with enhanced daily sampling. Analysis of over 3,000 hydrographic profiles following the AC reveals that potential vorticity and apparent oxygen utilization distributions are asymmetric outside the AC core, with enhanced subduction near the southeastern rim of the AC. There, the southward eddy flow advects newly ventilated mode water from the north into the main thermocline. Our results show that subduction by eddy lateral advection is comparable in magnitude to that by the mean flow—an effect that needs to be better represented in climate models.
Ultra-high gain diffusion-driven organic transistor
Authors: Torricelli Fabrizio , Colalongo Luigi , Raiteri Daniele , Kovács-Vajna Zsolt Miklós , Cantatore Eugenio 
Published: February 2016

AbstractEmerging large-area technologies based on organic transistors are enabling the fabrication of low-cost flexible circuits, smart sensors and biomedical devices. High-gain transistors are essential for the development of large-scale circuit integration, high-sensitivity sensors and signal amplification in sensing systems. Unfortunately, organic field-effect transistors show limited gain, usually of the order of tens, because of the large contact resistance and channel-length modulation. Here we show a new organic field-effect transistor architecture with a gain larger than 700. This is the highest gain ever reported for organic field-effect transistors. In the proposed organic field-effect transistor, the charge injection and extraction at the metal–semiconductor contacts are driven by the charge diffusion. The ideal conditions of ohmic contacts with negligible contact resistance and flat current saturation are demonstrated. The approach is general and can be extended to any thin-film technology opening unprecedented opportunities for the development of high-performance flexible electronics.
Three-dimensional porous carbon composites containing high sulfur nanoparticle content for high-performance lithium–sulfur batteries
Authors: Li Guoxing , Sun Jinhua , Hou Wenpeng , Jiang Shidong , Huang Yong , Geng Jianxin 
Published: February 2016

AbstractSulfur is a promising cathode material for lithium–sulfur batteries because of its high theoretical capacity (1,675 mA h g−1); however, its low electrical conductivity and the instability of sulfur-based electrodes limit its practical application. Here we report a facile in situ method for preparing three-dimensional porous graphitic carbon composites containing sulfur nanoparticles (3D S@PGC). With this strategy, the sulfur content of the composites can be tuned to a high level (up to 90 wt%). Because of the high sulfur content, the nanoscale distribution of the sulfur particles, and the covalent bonding between the sulfur and the PGC, the developed 3D S@PGC cathodes exhibit excellent performance, with a high sulfur utilization, high specific capacity (1,382, 1,242 and 1,115 mA h g−1 at 0.5, 1 and 2 C, respectively), long cycling life (small capacity decay of 0.039% per cycle over 1,000 cycles at 2 C) and excellent rate capability at a high charge/discharge current.
A silicon-based surface code quantum computer
Authors: O’Gorman Joe , Nickerson Naomi H , Ross Philipp , Morton John JL , Benjamin Simon C 
Published: February 2016

AbstractIndividual impurity atoms in silicon can make superb individual qubits, but it remains an immense challenge to build a multi-qubit processor: there is a basic conflict between nanometre separation desired for qubit–qubit interactions and the much larger scales that would enable control and addressing in a manufacturable and fault-tolerant architecture. Here we resolve this conflict by establishing the feasibility of surface code quantum computing using solid-state spins, or ‘data qubits’, that are widely separated from one another. We use a second set of ‘probe’ spins that are mechanically separate from the data qubits and move in and out of their proximity. The spin dipole–dipole interactions give rise to phase shifts; measuring a probe’s total phase reveals the collective parity of the data qubits along the probe’s path. Using a protocol that balances the systematic errors due to imperfect device fabrication, our detailed simulations show that substantial misalignments can be handled within fault-tolerant operations. We conclude that this simple ‘orbital probe’ architecture overcomes many of the difficulties facing solid-state quantum computing, while minimising the complexity and offering qubit densities that are several orders of magnitude greater than other systems.
Weak value amplification: a view from quantum estimation theory that highlights what it is and what isn’t
Authors: Torres Juan P. , Salazar-Serrano Luis José 
Published: February 2016

AbstractWeak value amplification (WVA) is a concept that has been extensively used in a myriad of applications with the aim of rendering measurable tiny changes of a variable of interest. In spite of this, there is still an on-going debate about its true nature and whether is really needed for achieving high sensitivity. Here we aim at helping to clarify the puzzle, using a specific example and some basic concepts from quantum estimation theory, highlighting what the use of the WVA concept can offer and what it can not. While WVA cannot be used to go beyond some fundamental sensitivity limits that arise from considering the full nature of the quantum states, WVA can notwithstanding enhance the sensitivity of real and specific detection schemes that are limited by many other things apart from the quantum nature of the states involved, i.e. technical noise. Importantly, it can do that in a straightforward and easily accessible manner.
Vagus Nerve Stimulation Improves Cardiac Function by Preventing Mitochondrial Dysfunction in Obese-Insulin Resistant Rats
Authors: Samniang Bencharunan , Shinlapawittayatorn Krekwit , Chunchai Titikorn , Pongkan Wanpitak , Kumfu Sirinart , Chattipakorn Siriporn C. , KenKnight Bruce H. , Chattipakorn Nipon 
Published: February 2016

AbstractLong-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant condition is not known. We determined the effects of VNS on metabolic parameters, heart rate variability (HRV) and LV function in obese-insulin resistant rats. Male Wistar rats were fed with HFD for 12 weeks and were randomly divided into sham and VNS groups. VNS was applied for the next 12 weeks. Echocardiography, blood pressure and HRV were examined. Blood samples were collected for metabolic parameters. At the end, the heart was removed for determination of apoptosis, inflammation, oxidative stress and cardiac mitochondrial function. VNS for 12 weeks significantly decreased plasma insulin, HOMA index, total cholesterol, triglyceride, LDL and visceral fat. Serum adiponectin was significantly increased in the VNS group. VNS also significantly decreased blood pressure, improved HRV and LV function, decreased cardiac MDA, TNF-α and Bax levels and improved cardiac mitochondrial function. VNS improves metabolic and hemodynamic parameters and the LV function via its ability against apoptosis, inflammation and oxidative stress and preserved cardiac mitochondrial function in obese-insulin resistant rats.
Cell wall as a target for bacteria inactivation by pulsed electric fields
Authors: Pillet Flavien , Formosa-Dague Cécile , Baaziz Houda , Dague Etienne , Rols Marie-Pierre 
Published: February 2016

AbstractThe integrity and morphology of bacteria is sustained by the cell wall, the target of the main microbial inactivation processes. One promising approach to inactivation is based on the use of pulsed electric fields (PEF). The current dogma is that irreversible cell membrane electro-permeabilisation causes the death of the bacteria. However, the actual effect on the cell-wall architecture has been poorly explored. Here we combine atomic force microscopy and electron microscopy to study the cell-wall organization of living Bacillus pumilus bacteria at the nanoscale. For vegetative bacteria, exposure to PEF led to structural disorganization correlated with morphological and mechanical alterations of the cell wall. For spores, PEF exposure led to the partial destruction of coat protein nanostructures, associated with internal alterations of cortex and core. Our findings reveal for the first time that the cell wall and coat architecture are directly involved in the electro-eradication of bacteria.
Impact of external medium conductivity on cell membrane electropermeabilization by microsecond and nanosecond electric pulses
Authors: Silve Aude , Leray Isabelle , Poignard Clair , Mir Lluis M. 
Published: February 2016

AbstractThe impact of external medium conductivity on the efficiency of the reversible permeabilisation caused by pulsed electric fields was investigated. Pulses of 12 ns, 102 ns or 100 μs were investigated. Whenever permeabilisation could be detected after the delivery of one single pulse, media of lower conductivity induced more efficient reversible permeabilisation and thus independently of the medium composition. Effect of medium conductivity can however be hidden by some saturation effects, for example when pulses are cumulated (use of trains of 8 pulses) or when the detection method is not sensitive enough. This explains the contradicting results that can be found in the literature. The new data are complementary to those of one of our previous study in which an opposite effect of the conductivity was highlighted. It stresses that the conductivity of the medium influences the reversible permeabilization by several ways. Moreover, these results clearly indicate that electropermeabilisation does not linearly depend on the energy delivered to the cells.
Structural and functional attributes of malaria parasite diadenosine tetraphosphate hydrolase
Authors: Sharma Arvind , Yogavel Manickam , Sharma Amit 
Published: February 2016

AbstractMalaria symptoms are driven by periodic multiplication cycles of Plasmodium parasites in human red blood corpuscles (RBCs). Malaria infection still accounts for ~600,000 annual deaths and hence discovery of both new drug targets and drugs remains vital. In the present study, we have investigated the malaria parasite enzyme diadenosine tetraphosphate (Ap4A) hydrolase that regulates levels of signalling molecules like Ap4A by hydrolyzing them to ATP and AMP. We have tracked the spatial distribution of parasitic Ap4A hydrolase in infected RBCs and reveal its unusual localization on the infected RBC membrane in subpopulation of infected cells. Interestingly, enzyme activity assays reveal an interaction between Ap4A hydrolase and the parasite growth inhibitor suramin. We also present a high resolution crystal structure of Ap4A hydrolase in apo- and sulphate- bound state, where the sulphate resides in the enzyme active site by mimicking the phosphate of substrates like Ap4A. The unexpected infected erythrocyte localization of the parasitic Ap4A hydrolase hints at a possible role of this enzyme in purinerigic signaling. In addition, atomic structure of Ap4A hydrolase provides insights for selective drug targeting.
Nonlinear photomechanics of nematic networks: upscaling microscopic behaviour to macroscopic deformation
Authors: Chung Hayoung , Choi Joonmyung , Yun Jung-Hoon , Cho Maenghyo 
Published: February 2016

AbstractA liquid crystal network whose chromophores are functionalized by photochromic dye exhibits light-induced mechanical behaviour. As a result, the micro-scaled thermotropic traits of the network and the macroscopic phase behaviour are both influenced as light alternates the shape of the dyes. In this paper, we present an analysis of this photomechanical behaviour based on the proposed multiscale framework, which incorporates the molecular details of microstate evolution into a continuum-based understanding. The effects of trans-to-cis photoisomerization driven by actinic light irradiation are first examined using molecular dynamics simulations and are compared against the predictions of the classical dilution model; this reveals certain characteristics of mesogenic interaction upon isomerization, followed by changes in the polymeric structure. We then upscale the thermotropic phase-related information with the aid of a nonlinear finite element analysis; macroscopic deflection with respect to the wide ranges of temperature and actinic light intensity are thereby examined, which reveals that the classical model underestimates the true deformation. This work therefore provides measures for analysing photomechanics in general by bridging the gap between the micro- and macro-scales.
Pseudo-Hydrogen Passivation: A Novel Way to Calculate Absolute Surface Energy of Zinc Blende (111)/(͞1 ͞1 ͞1) Surface
Authors: Zhang Yiou , Zhang Jingzhao , Tse Kinfai , Wong Lun , Chan Chunkai , Deng Bei , Zhu Junyi 
Published: February 2016

AbstractDetermining accurate absolute surface energies for polar surfaces of semiconductors has been a great challenge in decades. Here, we propose pseudo-hydrogen passivation to calculate them, using density functional theory approaches. By calculating the energy contribution from pseudo-hydrogen using either a pseudo molecule method or a tetrahedral cluster method, we obtained (111)/"Equation missing" surfaces energies of Si, GaP, GaAs and ZnS with high self-consistency. This method quantitatively confirms that surface energy is determined by the number and the energy of dangling bonds of surface atoms. Our findings may greatly enhance the basic understandings of different surfaces and lead to novel strategies in the crystal growth.
Persistent current in a correlated quantum ring with electron-phonon interaction in the presence of Rashba interaction and Aharonov-Bohm flux
Authors: Monisha P. J. , Sankar I. V. , Sil Shreekantha , Chatterjee Ashok 
Published: February 2016

AbstractPersistent current in a correlated quantum ring threaded by an Aharonov-Bohm flux is studied in the presence of electron-phonon interactions and Rashba spin-orbit coupling. The quantum ring is modeled by the Holstein-Hubbard-Rashba Hamiltonian and the energy is calculated by performing the conventional Lang-Firsov transformation followed by the diagonalization of the effective Hamiltonian within a mean-field approximation. The effects of Aharonov-Bohm flux, temperature, spin-orbit and electron-phonon interactions on the persistent current are investigated. It is shown that the electron-phonon interactions reduce the persistent current, while the Rashba coupling enhances it. It is also shown that temperature smoothens the persistent current curve. The effect of chemical potential on the persistent current is also studied.