bluuebunny/crossref_metadata_2025_split huggingface dataset:
High prey capture efficiencies of oceanic epipelagic lobate and cestid ctenophores
Authors: Child Taylor , Costello John H , Gemmell Brad J , Sutherland Kelly R , Colin Sean P 
Published: September 2024

Abstract
Ctenophores are numerically dominant members of oceanic epipelagic communities around the world. The ctenophore community is often comprised of several common, co-occurring lobate and cestid genera. Previous quantifications of the amount of fluid that lobate ctenophores entrain in their feeding currents revealed that oceanic lobates have the potential for high feeding rates. In order to more directly examine the trophic role of oceanic lobate ctenophores, we quantified the encounter and retention efficiencies of several co-occurring species (Bolinopsis vitrea, Ocyropsis crystallina, Eurhamphea vexilligera and Cestum veneris) in their natural environments. Encounters and predator–prey interactions were video recorded in the field using specialized cameras and SCUBA techniques. The lobate species encountered, on average, 2.4 prey per minute and ingested 40% of these prey. This translated to an estimated ingestion rate of close to 1 prey per minute. Cestum veneris and most of the lobate species retained prey as efficiently as the voracious coastal lobate predator Mnemiopsis leidyi, suggesting that these oceanic species have a similar predation impact in their environments as M. leidyi does in coastal ecosystems. Hence, quantified in situ predatory-prey interactions indicate that epipelagic ctenophores have a significant impact on oceanic ecosystems worldwide.
Quantum efficiency of chloroplasts retained from food by the mixotrophic ciliate Strombidium rassoulzadegani
Authors: Grzywacz J , Gorbunov M , McManus G B 
Published: September 2024

Abstract
Strombidium rassoulzadegani is an oligotrich ciliate from coastal waters that retains functional chloroplasts from its algal diet. Using a Fluorescence Induction and Relaxation fluorometer, we measured the maximum quantum efficiency (QE) of Photosystem II in two algal foods, one chlorophyte and one cryptophyte, and in the chloroplasts retained by the ciliate. Within the ciliate, QE of the chloroplasts was about half the value (c. 0.3) of that in exponentially-growing, nutrient-replete algal cultures (0.5–0.6). Under starvation, when the ciliates were not able to replace aging chloroplasts, QE declined further, to values of 0.1–0.2. The rate of decline was similar at irradiances from 30–100 μmol m−2 s−1 and slightly faster in total darkness. Exposure of the ciliates to the Photosystem II inhibitor DCMU decreased growth rates much more strongly in chlorophyte-fed ciliates, compared to those fed the cryptophyte. The decline in the chlorophyte-fed ciliates was much greater than expected, given the small subsidy to growth provided by the retained chloroplasts, suggesting that their role in the ciliate’s metabolism may be more than just a photosynthetic boost.
Regulatory network of the late-recruited primary decarboxylase C4NADP-ME in sugarcane
Authors: Hua Xiuting , Shi Huihong , Zhuang Gui , Lan Yuhong , Zhou Shaoli , Zhao Dongxu , Lyu Ming-Ju Amy , Akbar Sehrish , Liu Jia , Yuan Yuan , Li Zhen , Jiang Qing , Huang Kaixin , Zhang Yating , Zhang Qing , Wang Gang , Wang Yu , Yu Xiaomin , Li Pinghua , Zhang Xingtan , Wang Jianping , Xiao Shenghua , Yao Wei , Ming Ray , Zhu Xin-Guang , Zhang Muqing , Tang Haibao , Zhang Jisen 
Published: September 2024

Abstract
In agronomically important C4 grasses, efficient CO2 delivery to Rubisco is facilitated by NADP-malic enzyme (C4NADP-ME), which decarboxylates malate in bundle sheath cells. However, understanding the molecular regulation of the C4NADP-ME gene in sugarcane (Saccharum spp.) is hindered by its complex genetic background. Enzymatic activity assays demonstrated that decarboxylation in sugarcane Saccharum spontaneum predominantly relies on the NADP-ME pathway, similar to sorghum (Sorghum bicolor) and maize (Zea mays). Comparative genomics analysis revealed the recruitment of 8 core C4 shuttle genes, including C4NADP-ME (SsC4NADP-ME2), in the C4 pathway of sugarcane. Contrasting to sorghum and maize, the expression of SsC4NADP-ME2 in sugarcane is regulated by different transcription factors (TFs). We propose a gene regulatory network for SsC4NADP-ME2, involving candidate TFs identified through gene coexpression analysis and yeast 1-hybrid experiment. Among these, ABA INSENSITIVE5 (ABI5) was validated as the predominant regulator of SsC4NADP-ME2 expression, binding to a G-box within its promoter region. Interestingly, the core element ACGT within the regulatory G-box was conserved in sugarcane, sorghum, maize, and rice (Oryza sativa), suggesting an ancient regulatory code utilized in C4 photosynthesis. This study offers insights into SsC4NADP-ME2 regulation, crucial for optimizing sugarcane as a bioenergy crop.
Histone deacetylase GhHDA5 negatively regulates Verticillium wilt resistance in cotton
Authors: Wei Chunyan , Wang Chaofan , Zhang Xin , Huang Weiyi , Xing Minghui , Han Chunyan , Lei Cangbao , Zhang Youpeng , Zhang Xiangyu , Cheng Kai , Zhang Xiao 
Published: September 2024

Abstract
Verticillium wilt (VW) caused by Verticillium dahliae (V. dahliae) is one of the most destructive diseases in cotton (Gossypium spp.). Histone acetylation plays critical roles in plant development and adaptive responses to biotic and abiotic stresses. However, the relevance of histone acetylation in cotton VW resistance remains largely unclear. Here, we identified histone deacetylase 5 (GhHDA5) from upland cotton (Gossypium hirsutum L.), as a negative regulator of VW resistance. GhHDA5 expression was responsive to V. dahliae infection. Silencing GhHDA5 in upland cotton led to improved resistance to V. dahliae, while heterologous expression of GhHDA5 in Arabidopsis (Arabidopsis thaliana) compromised V. dahliae tolerance. GhHDA5 repressed the expression of several lignin biosynthesis-related genes, such as 4-coumarate:CoA ligase gene Gh4CL3 and ferulate 5-hydroxylase gene GhF5H, through reducing the acetylation level of histone H3 lysine 9 and 14 (H3K9K14ac) at their promoter regions, thereby resulting in an increased deposition of lignin, especially S monomers, in the GhHDA5-silenced cotton plants. The silencing of GhF5H impaired cotton VW tolerance. Additionally, the silencing of GhHDA5 also promoted the production of reactive oxygen species (ROS), elevated the expression of several pathogenesis-related genes (PRs), and altered the content and signaling of the phytohormones salicylic acid (SA), jasmonic acid (JA), and strigolactones (SLs) after V. dahliae infection. Taken together, our findings suggest that GhHDA5 negatively regulates cotton VW resistance through modulating disease-induced lignification and the ROS- and phytohormone-mediated defense response.
Confidence and second-order errors in cortical circuits
Authors: Granier Arno , Petrovici Mihai A , Senn Walter , Wilmes Katharina A 
Published: September 2024

Abstract
Minimization of cortical prediction errors has been considered a key computational goal of the cerebral cortex underlying perception, action, and learning. However, it is still unclear how the cortex should form and use information about uncertainty in this process. Here, we formally derive neural dynamics that minimize prediction errors under the assumption that cortical areas must not only predict the activity in other areas and sensory streams but also jointly project their confidence (inverse expected uncertainty) in their predictions. In the resulting neuronal dynamics, the integration of bottom-up and top-down cortical streams is dynamically modulated based on confidence in accordance with the Bayesian principle. Moreover, the theory predicts the existence of cortical second-order errors, comparing confidence and actual performance. These errors are propagated through the cortical hierarchy alongside classical prediction errors and are used to learn the weights of synapses responsible for formulating confidence. We propose a detailed mapping of the theory to cortical circuitry, discuss entailed functional interpretations, and provide potential directions for experimental work.
The origin and function of arbitrary signals: Making false statements, having long hair, and smoking Virginia Slims
Authors: Wernerfelt Birger 
Published: September 2024

Abstract
We propose a model in which players take actions that run counter to social norms in part to announce their stand on a social controversy but also, and maybe mostly, to gain image benefits that allow them to join groups that are socially attractive to them. We give several examples, but the “election denial” debate is an important application: rather than assuming that proponents believe their claims to be true, it suggests that false statements can serve as symbolic actions and help them engage in self-branding for social and psychological gain. Specifically, the willingness to make a controversial statement can be a credible signal because untruth is ill-received by some members of society and therefore entails some costs. It is immaterial whether election deniers believe their claim to be true, but it is important that some members of society believe that it is false and therefore think poorly of those who make it: if there is social consensus about the truth of a statement, it cannot serve a signaling function. The same mechanism explains several other verbal and nonverbal signals associated with different sides of social controversies and analysis of those helps clarify the mechanism.
Association between neonatal mortality and births not weighed among 400 thousand institutional deliveries in 32 low- and middle-income countries
Authors: Karlsson Omar , Benski Caroline , Kapoor Mudit , Kim Rockli , Subramanian S V 
Published: September 2024

Abstract

Background
Low birthweight (LBW) children have a higher risk of neonatal mortality. All institutional deliveries, therefore, should be weighed to determine appropriate care. Mortality risk for newborns who are not weighed at birth (NWB) is unknown.

Methods
This paper used logit regression models to compare the odds of death for NWB neonates to that of other neonates using data on 401 712 institutional births collected in Demographic and Health Surveys from 32 low- and middle-income countries.

Results
In the pooled sample, 2.3% died in the neonatal period and 12% were NWB. NWB neonates had a high risk of mortality compared to normal birthweight children (Adjusted odds ratio [AOR] 5.8, 95% CI: 5.3, 6.5). The mortality risk associated with NWB was higher than for LBW. The neonatal mortality risk associated with NWB varied across countries from AOR of 2.1 (95% CI: 1.22, 3.8) in Afghanistan to 94 (95% CI: 22, 215) in Gabon. In the pooled sample, the 12% of children who were NWB accounted for 37% of all neonatal deaths.

Conclusions
The association between NWB and neonatal mortality may suggest a need to focus on the quality of institutions related to newborn care. However, further studies are needed to determine causality. A health emergency or death may also cause NWB.
The Brand Premium
Authors: Boustanifar Hamid , Kang Young Dae 
Published: September 2024

Abstract
We highlight the limitations of using cumulative advertising expenses as an input measure of brand value. Using two output measures—Interbrand’s data and a novel text-based measure—we find that an equal-weighted portfolio of top brands yields an annual abnormal return of 3%. The excess returns are driven by companies that develop their brands internally. Intangible factors proposed in the literature have no explanatory power for the premium. Analysts underestimate the future earnings of top brands, leading to significant excess returns following earnings announcements. We find no abnormal returns associated with the input measure of brand value. (JEL G4, G12, G14, M41)
Novel deep-learning analysis for connective tissue disease—related interstitial lung disease extent assessment on CT: a preliminary cross-sectional study
Authors: Ito Yuhei , Ichikawa Yasutaka , Murashima Shuichi , Sakuma Hajime , Iwasawa Tae , Arinuma Yoshiyuki , Nakajima Ayako 
Published: September 2024

Abstract

Objectives
Physician’s evaluation of interstitial lung disease (ILD) extension with high-resolution CT (HRCT) has limitations such as lack of objectivity and reproducibility. This study aimed to investigate the utility of computer-based deep-learning analysis using QZIP-ILD® software (DL-QZIP) compared with conventional approaches in CTD-related ILD.

Methods
Patients with CTD–ILD visiting our Rheumatology Centre between December 2020 and April 2024 were recruited. Quantitative scores, including the percentage of lung involvement in ground-glass opacity (QGG), total fibrotic lesion (QFIB), and overall ILD extension encompassing both QGG and QFIB (QILD), calculated by DL-QZIP, were compared with semiquantitative visual method, employing intraclass correlation coefficients (ICC). We compared the capability of QILD scores to distinguish patients with forced vital capacity (FVC) % &lt;70 in both methods determined by the area under the curve (AUC) by the receiver-operating characteristic curve analysis and DeLong’s test.

Results
Eighty patients (median age, 66 years; 14 men) were included. Median QGG, QFIB and QILD scores were 3.45%, 2.19% and 5.35% using DL-QZIP, and 3.25%, 4.06% and 8.48% using visual method, respectively. Correlations between DL-QZIP and visual method were 0.75 for QGG, 0.61 for QFIB and 0.75 for QILD. The AUC of QILD scores for FVC% &lt;70 was significantly higher with DL-QZIP (0.833) compared with visual method (0.660) (P &lt; 0.01).

Conclusion
QZIP-ILD® demonstrates superior capability in distinguishing patients with a radiological scenario correlated to severe physiological impairment, while showing relatively good correlations in quantifying the extent on HRCT compared with conventional method in CTD–ILD.
Imaging findings in cardiovascular involvements of IgG4-related disease: a systematic review study
Authors: Ghaffari Jolfayi Amir , Salmanipour Alireza , Heshmat-Ghahdarijani Kiyan , Meshgi Shahla , Dastmardi Maedeh , Salehabadi Ghazaleh , Azimi Amir , Bazargany Mohammad Hossein Mozafary , Roudsari Peyvand Parhizkar , Mahmoodiyeh Behnaz , Mohammadzadeh Ali 
Published: September 2024

Abstract

Background
Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by IgG4-positive plasma cell infiltration that can affect multiple organs, including the cardiovascular system. The diagnosis of IgG4-RD relies on a combination of clinical, serological, radiological and pathological findings. However, due to the varied and insidious clinical presentations, normal IgG4 levels in a significant percentage of patients and frequent multi-organ involvement, imaging plays a crucial role in the diagnosis of IgG4-RD. The aim of this study is to comprehensively examine the imaging findings in IgG4-related cardiovascular disease for accurate diagnosis and appropriate treatment.

Methods
A systematic search was conducted across the electronic databases PubMed, Scopus, Embase and Web of Science, to 1 September 2023, following PRISMA guidelines, searching for studies reporting detailed cardiovascular imaging findings in IgG4-RD.

Results
The search yielded 68 studies (60 case reports, 5 case series, 2 cross-sectional, 1 case–control) with 120 cases of cardiovascular IgG4-RD. Most of the cases were male, averaging 62.8 years. The common initial symptoms were dyspnoea and chest pain. The most common imaging finding was vasculopathy, including vessel wall thickening, periarteritits, periaortitis, aortitis, stenosis, ectasia, aneurysm formation, intramural haemorrhage, fistula formation and dissection, followed by pericardial involvement and mediastinal masses. Case series and cross-sectional studies also showed vasculopathy to be the most common finding on various imaging modalities, including angiography and PET/CT, highlighting the complex pathology of IgG4-RD.

Conclusion
This study evaluated current IgG4-RD articles, revealing a higher prevalence in men and vasculopathy as the most common cardiovascular complication.
Psychometric examination of the patient-reported outcome measurement information system parent proxy pediatric sleep measures from early childhood to adolescence in a nationally representative Spanish sample
Authors: Becker Stephen P , Burns G Leonard , Montaño Juan José , Servera Mateu 
Published: September 2024

Abstract

Study Objectives
To use a nationally representative sample to (1) evaluate the factor structure of the patient-reported outcome measurement information system (PROMIS) parent proxy pediatric sleep scales (Spanish translation), (2) examine the invariance of these scales across sex and across different developmental periods of childhood and adolescence, (3) confirm the information and precision of the scales using item response theory (IRT), and (4) provide age-based normative information.

Methods
Parents of a nationally representative sample of 5525 Spanish children and adolescents ages 5–16 years (56.1% boys) completed the Spanish translation parent proxy short versions of the sleep disturbance and sleep-related impairment scales. We conducted confirmatory factor analyses, invariance analyses, and graded-response IRT analyses.

Results
CFAs conducted separately on males and females within three age groups (early childhood: ages 5–8 years; middle childhood: ages 9–12 years; adolescence: ages 13–16 years) indicated all items had a substantial loading with one exception (the sleep continuity item [“my child slept through the night”] had a substantially lower loading and was removed for subsequent analyses). The scores on the two scales demonstrated invariance across sex within each age group. Using IRT analyses, both scales showed a high degree of information and precision from slightly below the trait means to slightly above two standard deviations above the trait means.

Conclusions
The strong psychometric properties of the short versions of the parent proxy PROMIS pediatric sleep disturbance and sleep-related impairment scales, coupled with age-based norms, suggest these scales are likely to be useful for research and clinical applications.
Evaluation of ATP bioluminescence for rapid determination of farrowing room cleanliness after pressure washing at a commercial sow farm
Authors: Johnson Danielle C , Leal Leonardo A , Perez Jeremy G , Segundo Diana , Welch Michael W , Parr Eric , Meyer Matthew , Hedblom Grant A , Lopez-Velasco Gabriela , Mayo-Gibbons Mackenzie , Molitor April , Classen Dyneah M , Dillard Molly , Boler Dustin D 
Published: September 2024

Abstract
Rotavirus and other pathogenic microorganisms are known to cause scours, respiratory infection, and increased mortality, spread from pig to pig via contaminated equipment, insuffcient washing, and improper disinfection processes in farrowing rooms on commercial sow farms. Pig producers have adopted cleaning procedures and biosecurity policies as an attempt to ensure farrowing rooms are free of infectious organisms before the next group of sows is introduced. Adenosine triphosphate (ATP) bioluminescence has been used in other industries to provide real-time feedback on surface cleanliness through the detection of ATP from organic sources. That technology may provide producers a way of objectively characterizing a farrowing room’s suitability for a new group of sows to be moved into the farrowing room. Three ATP luminometers (Charm Sciences novaLUM II-X, 3M Clean Trace, and Neogen AccuPoint) were used to estimate relationships between ATP bioluminescence relative light units (RLU) and coliform plate counts (CPC). Five farrowing crate locations and the room entryway floor were swabbed to determine locations within a farrowing crate that can accurately estimate room cleanliness. Coliform plate counts were strongly correlated with Charm novaLUM II-X RLU (r = 0.70, P &lt; 0.01). The Clean-Trace CPCs and RLU (r = 0.48, P &lt; 0.01) were moderately correlated. There was a weak correlation between CPCs and AccuPoint RLU (r = 0.32, P &lt; 0.01). The greatest area of surface contamination was the entryway floor and the sow feeder. Because CPCs and luminometer RLU were correlated, statistical process control charts were developed to provide cleanliness thresholds based on RLU values. Based on an adjusted 3σ from the mean RLU critical limit, 7.7% of crates for the Charm novaLUM II-X, 10.6% of crates for the 3M Clean Trace, and 0% of crates for the Neogen AccuPoint would have failed the critical limit for the sow feeder cleanliness thresholds. Using a similar approach, 11.4% of crates for the Charm novaLUM II-X, 10.5% of crates for the 3M Clean Trace, and 15.2% of crates for the Neogen AccuPoint would have failed the critical limit for the crate sorting bar cleanliness thresholds. These data suggest that ATP bioluminescence may be a reliable method to monitor cleaning effectiveness in farrowing rooms on commercial sow farms. Bioluminescence is a monitoring tool that should be used in conjunction with periodic microbial validation to monitor procedures for cleaning and disinfection.
Katanin regulatory subunit B1 (KATNB1) regulates BTB dynamics through changes in cytoskeletal organization
Authors: Mao Bai‐Ping , Pan Mingdong , Shan Yuanyuan , Wang Ya‐Nan , Li Huitao , Wu Jinhan , Zhu Xuanjing , Hu Ende , Cheng C. Yan , Shangguan Wangning 
Published: September 2024

AbstractIn this study, we have explored the role of the KATNB1 gene, a microtubule‐severing protein, in the seminiferous epithelium of the rat testis. Our data have shown that KATNB1 expressed in rat brain, testes, and Sertoli cells. KATNB1 was found to co‐localize with α‐tubulin showing a unique stage‐specific distribution across the seminiferous epithelium. Knockdown of KATNB1 by RNAi led to significant disruption of the tight junction (TJ) permeability barrier function in primary Sertoli cells cultured in vitro with an established functional TJ‐barrier, as well as perturbations in the microtubule and actin cytoskeleton organization. The disruption in these cytoskeletal structures, in turn, led to improper distribution of TJ and basal ES proteins essential for maintaining the Sertoli TJ function. More importantly, overexpression of KATNB1 in the testis in vivo was found to block cadmium‐induced blood–testis barrier (BTB) disruption and testis injury. KATNB1 exerted its promoting effects on BTB and spermatogenesis through corrective spatiotemporal expression of actin‐ and microtubule‐based regulatory proteins by maintaining the proper organization of cytoskeletons in the testis, illustrating its plausible therapeutic implication. In summary, Katanin regulatory subunit B1 (KATNB1) plays a crucial role in BTB and spermatogenesis through its effects on the actin‐ and microtubule‐based cytoskeletons in Sertoli cells and testis, providing important insights into male reproductive biology.