bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comportamiento del concreto reforzado con fibras de acero ZP-306 sometido a esfuerzos de compresión
Authors: Gallo Arciniegas Lina P , González Peñuela Giovanni , Carrillo León Julián 
Published: December 2015

<span>En Colombia, el uso del concreto reforzado con fibras de acero (CRFA) es muy limitado,</span><span>debido a que en el país no existe suficiente evidencia experimental y requisitos reglamentarios </span><span>al respecto. En el artículo se presentan los resultados de una investigación experimental y analítica sobre el comportamiento del CRFA elaborado con fibras ZP-306, sometidas a esfuerzos de compresión. El estudio involucra la revisión y discusión de los modelos disponibles en la literatura, así como un programa experimental que incluye el ensayo de 48 especímenes. A partir de un análisis de regresión de los datos medidos, se proponen ecuaciones para estimar las principales propiedades mecánicas del CRFA, tales como resistencia a compresión, módulo de elasticidad y relación de Poisson. Las ecuaciones correlacionan las propiedades mecánicas con las principales características de las fibras de acero, tales como dosificación y relación de aspecto.</span>
Biosorción de Cd, Pb y Zn por biomasa pretratada de algas rojas, cáscara de naranja y tuna.
Authors: Vizcano Mendoza Lissette , Fuentes Molina Natalia 
Published: December 2015

<p>Debido a su movilidad en los ecosistemas y a su toxicidad para las formas superiores de vida, los metales pesados Cd, Pb y Zn son priorizados como unos de los contaminantes inorgánicos más importantes debido al alto riesgo que representan para el medio ambiente. Con el objeto de disminuir su concentración se diseñó un sistema para evaluar su remoción empleando biomasa de algas rojas, cáscaras de naranja (Citrus sp.) y tuna guajira (Opuntia sp.). Se estudió la influencia del pretratamiento y el empaquetamiento mediante ensayos tipo batch, en los que se emplearon soluciones de sodio y calcio. Se obtuvo como resultado una mayor capacidad de sorción de las algas modificadas con NaOH 0.1 N y de la naranja y la tuna con modificación sucesiva con NaOH y CaCl2 0.2 M, y una afección poco significativa (≤1%) del proceso de sorción al empacar la biomasa el placas planas de tul poliéster. La eficiencia de remoción se determinó mediante un reactor de flujo continuo de columna fija con un volumen líquido de 400 mL, 75 g de biomasa y tiempos de retención promedio de 1 y 2 h. Los resultados mostraron una eficiencia similar de las tres<br />biomasas para remover Cd y Pb, con promedios superiores al 95%, mientras que el Zn se removió con mejor eficiencia (62%) al emplear tuna modificada como sorbente. Finalmente, el material se calcinó a 700 °C con lo que se obtuvo una ceniza estable frente a soluciones ácidas, lo cual garantiza la captura de los metales removidos.</p>
Cáncer de cuello uterino: nuevos paradigmas dentro de un modelo integral de atención
Authors: Acosta-Peñaloza Jesús , Gaitán Duarte Hernando 
Published: December 2015

<span>En este número de la </span><em>Revista Colombiana de Obstetricia y Ginecología </em><span>presentamos tres estudios relacionados con el cáncer de cuello uterino. El primero, aborda los conocimientos y comportamientos referidos por las pacientes al recibir el resultado de una citología anormal; el segundo, describe la frecuencia del resultado de citología de células escamosas atípicas que no descartan lesión escamosa intraepitelial de alto grado (ASC-H), y el tercero, describe la calidad de vida en mujeres con diagnóstico de cáncer de cérvix. Esta coyuntura nos ha brindado la oportunidad de fijar un punto de vista acerca de cuáles son los problemas que se deben investigar a nivel local para mejorar la atención individual de las pacientes con esta patología y lograr mejores resultados a través de programas de salud pública en este campo, y, también, hacer una reflexión sobre el papel de los ginecólogos generales y subespecialistas en la prevención, el diagnóstico y el tratamiento de las lesiones precancerosas del cérvix como también del cáncer invasor de cuello uterino para mejorar los indicadores de impacto de esta patología en el país.</span>
Cemental Tear in an Autotransplanted Tooth That Had Been Functioning for 15 Years
Authors: Nagata Mutsumi , Kanie Takahito , Shima Kaori 
Published: December 2015

Introduction: Cemental tears have been described as specific types of root surface fractures that are seen infrequently but can cause rapid collapse of the periodontal tissue. However, to the best of the authors’ knowledge, cases of cemental tears in autotransplanted teeth and their recovery by autotransplantation have not been reported previously. This case report presents the clinical and histopathologic features of a rare case of a cemental tear that occurred on an autotransplanted tooth. This meant a total long‐term treatment course of 20 years involving two separate treatment procedures.Case Presentation: In 1995, the mandibular left second molar of a 40‐year‐old woman was extracted, and autogenous tooth transplantation was performed simultaneously using a third molar from the same side. Good clinical and radiologic progress was observed for >10 years after tooth transplantation. After discovery of a vertical bone defect in the distal area in 2006, conservative periodontal treatment was conducted on the diseased periodontal pocket over the course of several years. In 2010, autogenous tooth transplantation and a subsequent histopathologic examination of the extracted tooth were performed. After recovery treatment, a 5‐year follow‐up examination provided good results.Conclusions: This case report concerns the suspected contributing factors of cemental tears and the recovery treatment. When cemental tears are suspected after radiographic and other clinical examinations, interventional surgical treatment should be performed immediately. When autogenous tooth transplantation is performed, following careful consideration of the advantages and disadvantages of appropriate treatment and proper selection, continuous monitoring should be a prerequisite because of the possible occurrence of cemental tear.
The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature‐Induced Periodontitis
Authors: Balci Yuce Hatice , Karatas Ozkan , Aydemir Turkal Humeyra , Pirim Gorgun Emine , Ocakli Seda , Benli Ismail , Cayli Sevil 
Published: December 2015

Background: The aim of this study examines the effect of systemic melatonin administration on proinflammatory cytokine levels, apoptosis, alveolar bone loss (ABL), lipid metabolism, and diabetic control in in rats with diabetes mellitus (DM) and ligature‐induced periodontitis.Methods: Fifty‐two male Wistar rats were used in this study. Study groups were as follows: 1) non‐ligated control (NL, n = 6); 2) streptozotocin (STZ, n = 8); 3) STZ and melatonin (STZ+Mel, n = 8); 4) ligature (L, n = 6); 5) ligature and melatonin (L+Mel, n = 8); 6) STZ and ligature (STZ+L, n = 8); and 7) STZ, ligature, and melatonin (STZ+L+Mel, n = 8). DM was induced by intraperitoneal injection of a single dose of STZ (60 mg/kg). Melatonin was administered by intraperitoneal injection of a dose of 10 mg/kg/day for 4 weeks. Silk ligatures were placed subgingivally around the mandibular right first molars. The study period was 4 weeks, and animals were sacrificed at the end of 4 weeks. Morphometric analysis of bone loss was performed. Tissues were histopathologically examined. Inducible nitric oxide synthase (iNOS) and B‐cell lymphoma‐2‐associated X (bax) protein expressions, serum interleukin (IL)‐1β levels, and tartrate‐resistant acid phosphatase–positive (TRAP+) osteoclast numbers were also evaluated.Results: After 4 weeks, the highest ABL was observed in the STZ+L group, and the difference was significant (P <0.05). Systemically administered melatonin significantly decreased ABL in the STZ+L+Mel group compared with that in the STZ+L group (P <0.05). TRAP+ osteoclast numbers were the highest in the STZ+L group, and melatonin significantly decreased osteoclast numbers (P <0.05) but had no effect on iNOS, IL‐1β, or bax levels.Conclusions: Within the limits of this study, it can be concluded that systemic melatonin treatment may decrease osteoclastic activity and reduce ABL in the model using rats with DM.
Severity of Periodontitis and Metabolic Syndrome: Is There an Association?
Authors: Gomes‐Filho Isaac Suzart , das Mercês Magno Conceição , de Santana Passos‐Soares Johelle , Seixas da Cruz Simone , Teixeira Ladeia Ana Marice , Trindade Soraya Castro , de Moraes Marcílio Cerqueira Eneida , Freitas Coelho Julita Maria , Marques Monteiro Fernanda Maria , Barreto Maurício Lima , Pereira Vianna Maria Isabel , Nascimento Costa Maria da Conceição , Seymour Gregory John , Scannapieco Frank A. 
Published: December 2015

Background: Metabolic syndrome (MetS) is a major factor for the occurrence of cardiovascular events. Causal factors for MetS are not well defined or yet unidentified. Preliminary investigations suggest that infections and inflammation may be involved in the etiology of this syndrome. This study aims to estimate the association between the severity of periodontitis (exposure) and MetS (outcome).Methods: A cross‐sectional study was conducted with 419 participants recruited from the Diabetes and Hypertensive Treatment Center, Feira de Santana, Bahia, Brazil. After administration of a questionnaire, general and oral clinical examination and laboratory tests were performed. Diagnosis of periodontitis and MetS was performed according to various criteria. The analysis of the effect of periodontitis on MetS used logistic regression analysis with adjustment for confounders.Results: The prevalence of periodontitis was found to be between 34.61% and 55.37%, depending on the classification definitions used, and the prevalence of MetS ranged from 60.86% to 67.06%. In the group with periodontitis, 14.08% had severe and 41.29% had moderate levels of periodontitis. There was an association between severe periodontitis and MetS after adjustment for sex, age, household density, alcoholic beverage consumption, smoking habit, and cardiovascular disease (odds ratio ORadjusted_6 = 2.11, 95% confidence interval = 1.01 to 4.40, P = 0.05).Conclusions: The results suggest that periodontitis is associated with MetS, and that MetS prevalence is related to severe periodontitis.
Effect of Periodontal Therapy With Amoxicillin–Metronidazole on Pharyngeal Carriage of Penicillin‐ and Erythromycin‐Resistant Viridans Streptococci
Authors: Mombelli Andrea , Cionca Norbert , Almaghlouth Adnan , Cherkaoui Abdessalam , Schrenzel Jacques , Giannopoulou Catherine 
Published: December 2015

Background: Previous studies have focused on antibiotic resistance of Gram‐negative bacteria before and after periodontal therapy. The purpose of this analysis is to assess changes in resistance patterns of the commensal Gram‐positive microbiota. The viridans group streptococci (VGS) have been suggested to serve as reservoirs of resistance genes for more pathogenic streptococci and may be implicated in some non‐oral infections.Methods: In this randomized clinical trial, 80 patients with periodontitis are distributed randomly into two groups. In group A, patients received 375 mg amoxicillin and 500 mg metronidazole three times per day for 7 days during the non‐surgical treatment phase (T1). In group B, the antibiotics were administered during the surgical phase (T2). Resistance of VGS to penicillin and erythromycin was determined by the epsilometer test.Results: At baseline, VGS from 12.5% (group A) and 11.8% (group B) of patients had a minimum inhibitory concentration (MIC) >2 μg/mL to penicillin. Three months after T1, VGS from 15.6% and 16.7% of patients had an MIC >2 μg/mL, respectively. Six months after T2 VGS from 5.9% and 5.9% and 12 months after T2 VGS from 6.1% and 6.3% patients had an MIC >2 μg/mL. There was no effect of therapy with antibiotics, administered either in T1 or T2, on the carriage of penicillin‐resistant VGS. Erythromycin resistance was high at baseline and remained unchanged throughout the study. MICs for penicillin and erythromycin were correlated (P <0.05).Conclusion: Amoxicillin plus metronidazole did not significantly affect the resistance pattern of the VGS to penicillin or erythromycin.
Imaging the Lateral Roots of the Orange Tree using Three-dimensional GPR
Authors: Freeland Robert S. 
Published: December 2015

Citrus greening disease (Phytophthora nicotianae), also known as Huanglongbing (HLB), is a systemic disease caused by a bacterium that is vectored by a psyllid. Huanglongbing infection impacts citrus roots by its restructuring of the root bacterial community. The motivation of this study was to evaluate the diagnostic utility of employing high-frequency ground-penetrating radar (GPR) to survey orange tree [Citrus sinensis (L.) Osbeck] lateral structural roots. Of particular interest was GPR’s ability to discriminate the roots originating from neighboring trees, since these trees may be in a dissimilar stage of HLB infection. Tests groves are situated on the Ridge and Flatwood soils of Florida. The sandy soil and shallow root systems are considered ideal operating parameters for shallow GPR 3-D investigations.A 2,600-MHz antenna was found to effectively target and discriminate the larger structural roots originating from the target tree from those of its neighbors. The antenna reflections penetrated to 40-cm beneath the ground surface. On both landscapes, the larger 1st and 2nd order structural roots extended laterally outward within a root-zone layer approximately 10–30 cm beneath the surface. The roots increased in depth with their propagation outward. Smaller 2nd order and higher lateral roots were found in an upper layer that ranged approximately 5–5 cm beneath the surface. Those smaller roots provisioning near-surface fibrous roots were found concentrated above the larger structural roots. The roots imaged in the Ridge soils ran slightly deeper in both upper and lower root zones than the roots found in the Flatwood soils. The range of lateral rooting depths for both layers is slightly greater in the Ridge soils.
Gynaecological and other health problems of postmenopausal women and their health seeking behaviour in rural Terai, Nepal
Authors: Paudel I S , Bhattrai S , Adhikari P , Gautam R , Singh S B 
Published: December 2015

Background: There is very few data available in menopausal study done in Nepal. The data is even less on the various gynecological and medical problems postmenopausal women are suffering from. This study was done in Duhabi area, a community in Eastern Nepal, around the Comprehensive Health Service area of a community hospital under B.P Koirala Institute of Health Sciences.Objective: This study was done to document the various gynecological problems among the postmenopausal women and their relation with the socio-demographic characteristics.Methods: By using specific questionnaire, 234 post-menopausal women were interviewed regarding menopausal symptoms, other gynaecological problems and medical problems and their health seeking behaviour. Results: Our study showed that the most common symptoms among the post-menopausal women were loss of libido (53%) and hot flushes (41.5%). Other noted symptoms found were vaginal dryness (29.1%) and excessive vaginal bleeding (14.5%). The most common urinary symptoms were urgency (34.2%), dysuria (17.1%) and incontinence (17.1%). Uterine prolapse was reported by 6.4% of respondents. The most common medical condition seen in our study was low back ache (70.1%). Despite majority (62%) seeking medical treatment for their symptoms only 1.7% of the respondents were using hormone replacement therapy.Conclusion: The prevalence of gynaecological problems among the post-menopausal women was high in our study with the main symptoms of loss of libido and hot flushes. Majority of women with postmenopausal symptoms sought medical care for their problems. Health Renaissance 2014;12(2): pp: 87-91
Foreign body stone in oesophagus: a unique case
Authors: Sah B P , Chettri S T , Prasad J N. , Gupta P P , Shah S P , Paudel D , Jaiswal R K 
Published: December 2015

Foreign body ingestion is a common occurrence in children and in specific high-risk groups. It is usually diagnosed based on a history of ingestion given by the patient or an observer. However, children and mentally retarded adults may be unable to give an accurate history, and a high index of suspicion must be maintained in these groups. We report a rare case of foreign body stone in an mentally retarded adult which presented with drooling and impaired feeds, thence enabling for high index for suspicion. Health Renaissance 2014;12(2): pp: 140-142
Development of microsatellite markers for the endangered Pedicularis ishidoyana (Orobanchaceae) using next‐generation sequencing
Authors: Cho Won‐Bum , Choi In‐Su , Choi Byoung‐Hee 
Published: December 2015

Premise of the study:Microsatellite primers were developed for Pedicularis ishidoyana (Orobanchaceae), an endangered and hemiparasitic plant that is narrowly endemic to Korea. Because its populations are threatened by loss of suitable habitat, conservation efforts are required.Methods and Results:We developed polymorphic microsatellite loci through reference mapping of 300‐bp paired‐end reads obtained from Illumina MiSeq data. In all, 74 primer pairs were designed and 32 were amplified. Of these, 18 pairs were polymorphic, with two to six alleles each occurring in 26 individual plants. Expected and observed heterozygosities ranged from 0.142 to 0.703 and from 0.077 to 0.615, respectively.Conclusions:These microsatellite markers are expected to be useful for studies of the population genetics of P. ishidoyana.
Cerebrospinal Fluid and Plasma Lopinavir Concentrations and Viral Response in Virologically Suppressed Patients Switching to Lopinavir/Ritonavir Monotherapy Once Daily
Authors: Tiraboschi Juan M , Knobel Hernando , Imaz Arkaitz , Villar Judith , Ferrer Elena , Saumoy Maria , González Alicia , Rozas Nerea , Vila Antonia , Niubó Jordi , Curto Jordi , Podzamczer Daniel 
Published: December 2015

Background Lopinavir/ritonavir (LPV/r) monotherapy is used in selected virologically suppressed HIV-infected patients. Some would prefer a once-daily (OD) dose instead of the usual twice-daily dose to favour adherence. However, trough concentrations of the drug in blood and particularly in cerebrospinal fluid (CSF) may not be adequate to maintain viral suppression. Methods Prospective, open-label pilot study to evaluate the efficacy and safety of LPV/r monotherapy OD. HIV-1-infected patients, virologically suppressed for at least 6 months were enrolled. HIV viral load (VL) was determined at baseline and at weeks 4, 8, 12, 16, 24, 36 and 48. Lumbar puncture was performed in a subgroup of patients to evaluate CSF VL and CSF LPV concentrations. Results A total of 21 patients were included. At week 48, 85.7% ( n=18) showed viral suppression (VL<40 copies/ml). Two patients had viral failure (9.5%) and a third was withdrawn from the study because of gastrointestinal symptoms. Nine patients were enrolled in the substudy. CSF VL was <40 copies/ml in all cases. Median (range) LPV concentration was 9.78 ng/ml (1.93–78.3) in CSF and 1,970 (154–16,700) ng/ml in plasma; the CSF/plasma ratio was 0.004 (0.001–0.186). Conclusions In this small pilot study, LPV/r monotherapy OD maintained plasma HIV RNA suppression at 48 weeks in most patients, with no cases of CSF viral escape. However, CSF LPV concentrations were close to the 50% inhibitory concentration threshold in several patients; hence, this intervention should be avoided in patients with advanced immune suppression and/or those individuals presenting with significant comorbidities such as hepatitis C coinfection.
Comparison of postoperative complications in advanced head and neck cancer patients receiving neoadjuvant chemotherapy followed by surgery versus surgery alone
Authors: Joshi Poonam , Joshi Amit , Prabhash Kumar , Noronha Vanita , Chaturvedi Pankaj 
Published: December 2015

Abstract
Background: Head and neck cancer is the third most common cancer in India with 60% presenting in advanced stages. There is the emerging role of neoadjuvant chemotherapy (NACT) in the management of these advanced cancers. There is a general perception that complication rates are higher with the use of NACT. Materials and Methods: This is a retrospectively collected data of head and neck cancer patients operated at our hospital from March 2013 to September 2014. A total of 205 patients were included in the study. These patients were studied in two groups. Group 1 included 153 patients who underwent surgery alone, and Group 2 included 52 patients who received 2-3 cycles of NACT followed by surgery. Results: The mean age of the population was 51 years in the Group 1 and 45 years in Group 2. The hospital stay and readmissions in postoperative period were similar in the two groups. In this study, the complication rate was 37.9% in the surgery patients and 30.8% in the NACT patients (P = 0.424). Conclusion: The postoperative complication rates in patients who received NACT followed by surgery were not significantly different from those who underwent surgery.
Increased Expression of ERCC2 Gene in Head and Neck Cancer is Associated with Aggressive Tumors: A Systematic Review and Case-Control Study
Authors: Zafeer Maryam , Mahjabeen Ishrat , Kayani Mahmood Akhtar 
Published: December 2015

Introduction The excision repair cross-complementation group 2 (ERCC2) ATP-dependent helicase is an essential member of the DNA repair pathway. It has been observed to be differentially expressed in different cancers, which shows its involvement in carcinogenesis. Aim In the present study we have tried to determine the association of expression patterns of this gene with head and neck carcinogenesis. Method We first carried out a systematic review of the available studies on the role of ERCC2 in head and neck cancer (HNC). In order to test the hypothesis that the expression patterns of XPD/ERCC2 play a critical role in HNC pathogenesis, we then conducted a population based case-control study on 81 head and neck tumor samples and adjacent normal-tissue control samples. Reverse transcriptase polymerase chain reaction (RT-PCR) and quantitative polymerase chain reaction (qPCR) were used to assess ERCC2 deregulation at the mRNA level. Result Expression analysis showed that the ERCC2 expression level was significantly upregulated (p<0.05) in HNC tissues compared with adjacent normal tissues. Furthermore, the expression pattern of ERCC2 was correlated with the expression pattern of Ki-67 and a significant correlation (r = 0.230, p<0.03) was observed between ERCC2 and Ki-67. Spearman's correlation also showed a significant correlation between ERCC2 expression and tumor stage (r = 0.271, p<0.02) and grade (r = 0.228, p<0.02) of HNC. Conclusions Our data suggest that deregulation of ERCC2 in HNC has the potential to predict a more aggressive cancer phenotype and may be considered a possible biomarker for improved diagnosis and prognosis of HNC.