bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neue Perspektiven des Sparkassenrechts
Authors: Oebbecke Janbernd 
Published: October 2024

Zusammenfassung
Die Rezension des Werkes
Sparkassengesetz Nordrhein-Westfalen, Kommentar. Von Marwan Hamdan und Christoph Landscheidt (Hrsg.). 2024. C. H. Beck, München. 590 S. ISBN 978-3-4068-1745-8. € 159.
erlaubt es, einen kritischen Blick nicht nur auf das besprochene Buch, sondern auch auf einige Aspekte seines Gegenstands, nämlich die kommunalen Sparkassen und ihren gesetzlichen Rahmen, und den Umgang der Autoren mit diesen Themen zu werfen. Dabei geht es um die Binnenorganisation, den Jahresabschluss und die Gewinnverwendung, also um Themen, bei denen kommunale Einflussnahme und kommunale Interessen eine besondere Rolle spielen. Die Aufsicht des Landes bindet die Sparkassen in die öffentliche Verwaltung ein, der Sparkassenverbund in die Sparkassenorganisation. Drängende Fragen betreffen die Geschäftspolitik. Derzeit steht die Struktur als kommunale Anstalten weniger im Fokus als dies in der Vergangenheit immer mal wieder der Fall war.
Nazi policy towards the Lithuanian lndustry and its results
Authors: Braslauskas Justinas 
Published: October 2024

The industrial organization during the period of Nazi occupation was influenced mainly by an external factor, Germany, and not by an internal development of the economy. Germany was an aggressor state whose objective was to gradually integrate the local economy into its own structure. Only those industrial enterprises which could find local raw materials and could offer products important for the occupants managed to continue their business operations during the years of German occupation. Other industrial enterprises were closed by the occupant authorities. Many private companies were closed by their owners or were on the verge of bankruptcy. The decrease in the number of industrial enterprises was one of the main causes of a rapid decline in this sphere of the economy. During the years of Nazi occupation, industrial workers lived under severe social conditions. Their salaries were extremely low; in most cases, they did not even earn a living wage. Due to difficult living conditions, expensive low-quality health care, and the spread of various diseases, the mortality rate among factory workers and office employees was on a constant increase. On the other hand, it is true that the Nazis, during the period of occupation, put much effort into industrial specialist training programs. This policy was part of their plan to annex Lithuania after the end of World War II. Besides, a bigger part of the Jewish population had already been exterminated, among them many outstanding specialists in this branch of the industry.
Costs of medical evacuation and transportation of First Nations Peoples and Inuit who travel for medical care in Canada: A systematic review
Authors: Radhaa Majd , Leason Jennifer , Twalibu Aisha , Davis Erin , Fletcher Claire Dion , Lawford Karen , Darling Elizabeth , Wylie Lloy , Couchie Carol , Simon Diane , John-Baptiste Ava 
Published: October 2024

Abstract
Objective
For First Nations people and Inuit who live on reserves or in rural and remote areas, a guideline requires their travel to urban centres once their pregnancy reaches 36–38 weeks gestation age to await labour and birth. While not encoded in Canadian legislation, this guideline—and invisible policy—is reinforced by the lack of alternatives. Research has repeatedly demonstrated the harm of obstetric evacuation, causing emotional, physical, and financial stress for pregnant and postpartum Indigenous women and people. Our objective was to describe the costs of obstetric evacuation, as reported in the literature.

Methods
We conducted a systematic review using online searches of electronic databases (Ovid EMBASE, CINAHL, Ovid Healthstar, PubMed, ScienceDirect, PROSPERO, and Cochrane Database of Systematic Reviews) and identified studies that reported costs related to medical evacuation or transportation in rural and remote Indigenous communities. We performed critical appraisal of relevant studies.

Synthesis
We identified 19 studies that met the inclusion criteria. The studies reported various types of cost, including direct, indirect, and intangible costs. Medical evacuation costs ranged from CAD $7714 to CAD $31,794. Indirect and intangible costs were identified, including lost income and lack of respect for cultural practices.

Conclusion
Costs associated with obstetric evacuation are high, with medical evacuation as the most expensive direct cost identified. Although we were able to identify a range of costs, information on financing and funding flows was unclear. Across Canada, additional research is required to understand the direct costs of obstetric evacuation to Indigenous Peoples and communities.
La imagen del jardín espiritual como medio de evangelización en la obra poética de Luisa de Carvajal y Mendoza / The image of spiritual garden as means for evangelization in Luisa de Carvajal y Mendoza’s poetic work
Authors: Escalante Varona Alberto 
Published: October 2024

En este artículo propongo un acercamiento a la función evangelizadora de la obra literaria de Luisa de Carvajal y Mendoza a través del análisis de uno de sus poemas. En las Redondillas espirituales de Silva, comprobaremos cómo el diálogo entre Silva y su amiga pastora se estructura como un discurso apelativo en el que la imagen del jardín espiritual se funde con la figura de Cristo como pastor. En esta transmisión del gozo espiritual se aprecia la voluntad de predicación que rigió buena parte de la vida de la autora, quien recurre para tal fin a todos los símbolos místicos que están a su alcance.In this paper, I propose an approaching to the evangelist function of Luisa of Carvajal and Mendoza’s poetic production, through the analysis of one of her poems. In her Redondillas espirituales de Silva we will find how the dialogue between Silva and his shepherd friend establish a conative discourse where the image of the spiritual garden merges with the figure of Christ as the Shepherd. In this transmission of spiritual joy, we can appreciate the preaching wish that ruled over the life of the author, who uses all the mystic topics that she knows for that purpose.Palabras clave: locus amoenus, poesía mística, predicación, jardín, martirio.Keywords: locus amoenus, mystic poetry, preaching, garden, martyrdom.DOI: http://dx.medra.org/10.17398/1886-4945.10.91
INVESTIGATION OF THE EFFECT OF PROCESSING ALLOGENEIC AND XENOGENIC BIOMATERIALS IN SUB- AND SUPERCRITICAL CARBON DIOXIDE ON THE ABILITY TO SUPPRESS CALCIFICATION
Authors: Perepelkin Evgeny I. , Britikov Dmitry V. , Zubko Alexander V. , Chashchin Ivan S. , Bakuleva Natalia P. , Dzhihiya Konstantin M. 
Published: October 2024

HighlightsHybrid decellularization of allografts in scCO2 with a small addition of the detergent Tween 80 is very effective in terms of reducing calcification.A special coating based on chitosan nanoparticles obtained and applied from the water/subcritical CO2 system makes it possible to significantly reduce calcification of the standard GA-stabilized pericardium. Aim. To conduct a comparative analysis of anticalcification properties of implants based on allo- and xeno-tissue after treatment in super- (scCO2) and subcritical carbon dioxide.Methods. We have performed a modification of the following structures: a) rat vessels by hybrid decellularization in scCO2 with detergents b) calf pericardium by direct coating of chitosan nanoparticles with silver from the water/carbon dioxide system under pressure (carbonic acid). Following that we have performed an in vivo calcification study on rats (n = 10 for each type of sample). To model the behavior of biomaterial in the human body, we have implanted allogeneic modified aorta into rats. To determine the calcium in the extracted samples, we have used spectrophotometric method to estimate the concentration of calcium. To assess the cytotoxicity of nanocoated pericardium samples, we have measured the impedance of cells populated on biomaterial samples was used.Results. The treatment of rat vessels in supercritical CO2 reduces the deposition of calcium salts by 30% compared to baseline allografts. Pericardium coated with chitosan nanoparticles can be characterized by a significant decrease in calcification – the biomatrix coated with Cht_Ag/TPP contains only (0.015 ± 0.005) wt.% of calcium salts, which is significantly lower compared with GA-stabilized pericardium with (0.070 ± 0.015) wt.% after the experiment. Biocomposites with nanocoating are characterized by similar cellular index compared to a sample of uncoated xeno-tissue. All samples exhibit a cytostatic effect, including nanocoated samples (Cht_Ag/TPP), which proves the encapsulation of silver in the polymer matrix and ensures the absence of negative effects on the body during normal functioning. The coating of biomatrix based on hollow chitosan nanoparticles contributes to an increase in cell proliferation.Conclusion. The use of supercritical technology for the purification of biomaterials, as well as the creation and application of polymer protective coatings in order to enhance the ability to suppress calcification looks very promising. At the same time, the use of such a “green” approach to the modification of bioprostheses is a more advantageous strategy relative to the standard generally accepted methods of their chemical modification.
TISSUE-ENGINEERED VASCULAR GRAFT: ASSESSMENT OF MATERIAL QUALITY AND ACTIVITY OF ANTI-TROMBOGENIC COATING
Authors: Senokosova Evgenia A. , Krivkina Evgenia O. , Akentieva Tatiana N. , Glushkova Tatiana V. , Koshelev Vladislav A. , Khanova Maryam Yu. , Antonova Larisa V. 
Published: October 2024

HighlightsThe original method of forming a hydrogel anti-trombogenic drug coating on the inner surface of a small diameter vascular graft did not affect the baseline structural, physical and mechanical properties of the product. Loading iloprost and heparin into the coating significantly improved the hemocompatibility of the material with respect to inhibition of platelet aggregation. Aim. To evaluate structural, physical and mechanical characteristics of a drug-eluting tissue-engineered vascular graft and the functional activity of its coating. Methods. Vascular grafts based on polycaprolactone and polyurethane with growth factors were manufactured by emulsion electrospinning. The modified coating on the inner surface of the graft consisted of a hydrogel layer loaded with iloprost and heparin. The surface structure was studied by scanning electron microscopy, physical and mechanical characteristics were studied using a universal Zwick/Roell testing machine, surface properties were studied by contact angle measurements and wettability. The functional activity of the modified coating was assessed with the help of indicators of maximum platelet aggregation upon contact with the material.Results. The results showed that forming the coating did not change the architectonics of the polymer matrix surface. The structure of the graft was represented by randomly directed micro- and nanofibers with heterogeneous pores and without deformation of material; the surface of the graft retained hydrophilicity (θ = 68.6 ± 11.85). We confirmed the success of surface modification of vascular graft by observing extremely low values of the maximum platelet aggregation upon contact of platelet-rich plasma with the surface of the graft (8,5 (7,2; 12,2) %). Depending on the conditions of their incubation in saline solution, we have noted the prolongation of the drug-releasing activity.Conclusion. The formation of anti-thrombogenic coating on the surface of the PCL/PU/GFmix/Ilo/Hep vascular graft did not negatively affect the structural characteristics or physical and mechanical properties, moreover, it significantly improved hemocompatibility in terms of inhibition of platelet aggregation.
SIGNIFICANCE ASSESSMENT OF LDL-CONTAINING CIRCULATUNG IMMUNE COMPLEXES IN DIAGNOSTICS AND PROGNOSTICATION OF CAROTID ATHEROSCLEROSIS
Authors: Orekhov Nikolay A. , Kirichenko Tatiana V. , Myasoedova Veronika A. , Omelchenko Andrey V. , Orekhov Alexander N. , Sobenin Igor A. 
Published: October 2024

HighlightsLow-density lipoprotein cholesterol (LDL)-containing circulating immune complexes (LDL-CIC) reflect impaired lipid metabolism and systemic inflammation.Serum level of LDL-CIC is sensitive and specific diagnostic and prognostic marker of carotid atherosclerosis.The combination of age and serum LDL-CIC is particularly valuable for the prognosis of carotid atherosclerosis. Aim. Recent studies suggested that increased level of low-density lipoprotein cholesterol (LDL)-containing circulating immune complexes (LDL-CIC) might have high diagnostic value in regards to clinical and asymptomatic atherosclerosis. The aim was to study prognostic significance of LDL-CIC.Methods. The two-year study included 98 men. Each included patient underwent the following studies: carotid intima-media thickness, total cholesterol, low- and high-density lipoprotein cholesterol, triglycerides, and LDL-CIC.Results. Among these parameters, low-density lipoprotein cholesterol and LDL-CIC were significantly associated with severity and prognosis of carotid atherosclerosis. LDL-CIC has the highest sensitivity and specificity in diagnostics of carotid atherosclerosis when combined with age. Other parameters do not affect the prognostic significance of LDL-CIC.Conclusion. The results suggest that LDL-CIC can be used for diagnostics and prognosis of atherosclerosis.
TRANSTIRETINIC (ATTR) AMYLOID CARDIOMYOPATHY NOWADAYS. A COMMON DISEASE WITH OPEN PROBLEMS
Authors: Golubovskaya Darya P. , Pecherina Tamara B. , Barbarash Olga L. 
Published: October 2024

HighlightsThe article presents a review of literature data devoted to the latest changes in the epidemiology and features of transthyretin (ATTR) amyloidosis. The review highlights factors that increase the likelihood of a patient having this disease, emphasizing the group of high-risk patients, and discusses issues of non-invasive diagnostic management of a patient with cardiac amyloidosis in clinical practice. AbstractTransthyretin (ATTR) amyloid cardiomyopathy is a severe infiltrative heart disease that followed by heart failure (HF) with a preserved and moderately reduced left ventricular ejection fraction and a restrictive phenotype. It negatively affects the prognosis and quality of life of patients. In the absence of timely treatment, the median survival is 2–3.5 years for different forms of ATTR amyloidosis. Advances in noninvasive cardiac imaging, availability of genetic testing, identification of «high risk» groups of patients with amyloid cardiomyopathy, and the emergence of new methods of treatment have increased the detection rate of the disease, but only at its later stages (when a patient suffers from heart failure and pronounced hypertrophic cardiomyopathy), which negatively affects the prognosis of patients. Therefore, an interdisciplinary approach, vigilance, and timely diagnostics are crucial for both ATTR amyloidosis and the problem of heart failure in general.
Assessment of Specific Biomarkers’ Profile and Structural, Functional Parameters of the Left Ventricle in Patients With Lymphomas Undergoing Antitumor Therapy
Authors: Sokolova I. Ya. , Murtuzaliev Sh. M. , Kardovskaya S. A. , Shchendrygina A. A. , Markin P. A. , Appolonova S. A. , Kulagina T. Yu. , Zhigulina O. A. , Khabarova N. V. , Belenkov Yu. N. , Ilgisonis I. S. 
Published: October 2024

Aim. To evaluate the dynamics of specific biomarkers for cardiotoxicity, endothelial dysfunction, fibrosis, systemic inflammation, and morpho-functional alterations in the left ventricular (LV) myocardium in patients with newly diagnosed lymphomas during 6 courses of polychemotherapy (PCT).Material and methods. The study included 30 patients with newly diagnosed lymphomas. All patients were evaluated for laboratory markers of cardiotoxicity at baseline and after 6 courses of chemotherapy (6 months), including N-terminal pro-brain natriuretic peptide (NT-proBNP), high-sensitivity troponin I (hsTnI), endothelin-1 (ET-1), circulating cardiac biomarker ST-2, high-sensitivity C-reactive protein (hsCRP), interleukin-6 (IL-6), and LV structural and functional echocardiographic (EchoCG) parameters.Results. The changes in NT-proBNP and hsTnI concentrations during 6 courses of PCT were not statistically significant. Comparison of the baseline values with those after 6 courses of PCT showed increases in the median concentrations of ET-1 (3.38 and 5.5 pg/ml, respectively; p=0.438) and ST-2 (12.21 and 26.75 ng/ml, respectively; p=0.687). Markers of systemic inflammation were significantly decreased after 6 courses of PCT: the median CRP decreased from 15.2 to 0.72 mg/ml (p=0.006), and the median IL-6 decreased from 12.2 to 5.1 pg/ml (p=0.034). EchoCG data revealed a statistically significant impairment of the LV diastolic function parameters (E/A; E/e’ lateral; E/e’ average; left atrial volume index; isovolumic relaxation time). A moderate direct correlation was found between the ET-1 concentration and the isovolumic relaxation time at baseline and after 6 courses of PCT, respectively (r1 = 0.387, p=0.047 and r2 = 0.391, p=0.035). No changes in the LV systolic function were observed.Conclusion. The study showed that patients with lymphoproliferative diseases had no signs of cardiotoxicity during PCT according to the accepted criteria. This study described and highlighted for the first time the interrelation of endothelial dysfunction, profibrotic status, and LV diastolic dysfunction as manifestations of cardiovascular toxicity in patients with lymphoproliferative diseases. It is advisable to supplement the integrated strategies for the prevention and monitoring of PCT cardiovascular toxicity with a thorough evaluation of instrumental parameters of diastolic dysfunction for timely initiation/correction of cardioprotective therapy.
The science behind monosodium glutamate: Flavor modulation, food palatability, and potential health effects
Authors: Dwivedi Mahendra 
Published: October 2024

Monosodium glutamate (MSG) is widely used as a flavor enhancer in food, known for its ability to modulate umami taste and improve overall food palatability. Despite its recognized benefits in the food industry, concerns about its safety and potential health effects have sparked widespread debate. This systematic review aims to provide an in-depth analysis of the molecular mechanisms underlying MSG's flavor-enhancing properties, its role in food palatability, and the scientific evidence surrounding its health impacts. To review the current state of knowledge regarding: 1. The molecular chemistry and mechanism of MSG in flavor modulation. 2. The role of MSG in enhancing food palatability and consumer preferences. 3. he safety assessments and potential health effects of MSG, including both benefits and concerns. 4. MSG's future applications in food science, particularly in low-sodium formulations, food security, and geriatric nutrition. A comprehensive search of peer-reviewed literature was conducted using databases such as PubMed, Web of Science, and Google Scholar. Studies focusing on MSG’s chemistry, its application in food, sensory studies, and health-related research were included. Regulatory assessments from food safety agencies (FDA, WHO, EFSA) were also reviewed. Flavor Modulation: MSG enhances the umami taste by interacting with specific glutamate receptors (T1R1/T1R3), contributing to a balanced flavor profile in various cuisines. It is especially effective in reducing the need for excess salt and fat in processed foods while maintaining palatability.Food Palatability: Sensory studies show that MSG significantly improves food satisfaction, particularly in low-sodium or low-fat products. Consumers often prefer MSG-enriched foods due to enhanced flavor perception and texture.Health Impacts: Regulatory bodies have classified MSG as safe for consumption, with no conclusive evidence linking it to neurotoxicity or adverse metabolic effects at typical dietary levels. Some studies suggest MSG may aid in reducing sodium intake and improving food palatability in special populations, such as the elderly.Public Perception: Despite the scientific consensus on its safety, public concerns remain, largely fueled by misconceptions about "Chinese Restaurant Syndrome" and misleading media reports. MSG plays a pivotal role in modern food science as a safe and effective flavor enhancer. While public concerns persist, scientific evidence supports its safety and potential health benefits when used appropriately. Further research should focus on long-term health effects, innovative applications in low-sodium food formulations, and educational initiatives to address public misconceptions about MSG.
Prolonged intravascular hemolysisand vitamin B12 deficiencyafter parasiticclearance in a case of complicated falciparum malaria
Authors: Dastidar Aheli Ghosh , Chandra Sandip Kumar , Bandyopadhyay Syamasis , Dutta Aloke , Samanta Rajeshwar , Ganguly Supratim 
Published: October 2024

Malaria is still a very threatening disease to tackle in India. The potential array of complications which can arise due to this infection is appreciably wide and many of these complications pose a significant life risk. Our patient, a 35-year-old gentleman presented with a complicated falciparum malaria infection. He developed an acute kidney insult, thrombocytopenia, septic shock, acidosis and anemia with a parasitemia of 3%. He was managed with artemisinin based therapy as per the latest guidelines and gradually his complications got tackled and he achieved parasitic clearance. But his anemia kept on worsening after fever resolution and parasitic clearence and he developed a picture of persistent intravascular hemolysis after recovery from the infection. Also, interestingly, his vitamin B12 level was significantly low despite being on a non-vegetarian diet and receiving oral B12 supplementation. This case highlights the importance of monitoring hemoglobin levels even after complete parasitic clearance as the intravascular hemolysis can also arise due to the usage of artemisinin based therapy, an entity called as post artemisinin delayed hemolysis. Also, this case showed the coexistence of low B12 state and poor B12 absorption in a young gentleman who had previously normal B12 levels. The association between malaria and poor B12 absorption needs to be explored further by more studies. Any association found can help in recommendations of B12 supplementation in malaria cases.