bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Supernovae Analysis Application (SNAP)
Authors: Bayless Amanda J. , Fryer Chris L. , Wollaeger Ryan , Wiggins Brandon , Even Wesley , Rosa Janie de la , Roming Peter W. A. , Frey Lucy , Young Patrick A. , Thorpe Rob , Powell Luke , Landers Rachel , Persson Heather D. , Hay Rebecca 
Published: September 2017

Abstract
The SuperNovae Analysis aPplication (SNAP) is a new tool for the analysis of SN observations and validation of SN models. SNAP consists of a publicly available relational database with observational light curve, theoretical light curve, and correlation table sets with statistical comparison software, and a web interface available to the community. The theoretical models are intended to span a gridded range of parameter space. The goal is to have users upload new SN models or new SN observations and run the comparison software to determine correlations via the website. There are problems looming on the horizon that SNAP is beginning to solve. For example, large surveys will discover thousands of SNe annually. Frequently, the parameter space of a new SN event is unbounded. SNAP will be a resource to constrain parameters and determine if an event needs follow-up without spending resources to create new light curve models from scratch. Second, there is no rapidly available, systematic way to determine degeneracies between parameters, or even what physics is needed to model a realistic SN. The correlations made within the SNAP system are beginning to solve these problems.
The Starspots of HAT-P-11: Evidence for a Solar-like Dynamo
Authors: Morris Brett M. , Hebb Leslie , Davenport James R. A. , Rohn Graeme , Hawley Suzanne L. 
Published: September 2017

Abstract
We measure the starspot radii and latitude distribution on the K4 dwarf HAT-P-11 from Kepler short-cadence photometry. We take advantage of starspot occultations by HAT-P-11’s highly misaligned planet to compare the spot size and latitude distributions to those of sunspots. We find that HAT-P-11’s spots are distributed in latitude much like sunspots near the solar activity maximum, with a mean spot latitude of ≈16° ± 1°. The majority of HAT-P-11’s starspots have physical sizes that closely resemble the sizes of sunspots at solar maximum. We estimate the mean spotted area coverage on HAT-P-11 to be

, roughly two orders of magnitude greater than the typical solar spotted area.
RFLP clusters of rifampicin resistant and susceptible Mycobacterium tuberculosis strains in Western province of Sri Lanka
Authors: Adikaram Chamila Priyangani , Wijesundera Sandya Sulochana , Perera Jennifer 
Published: September 2017

Introduction: Continuous studies on genetic diversity of Mycobacterium tuberculosis could enhance the awareness on transmission, control and prevention of tuberculosis (TB). In this study, we investigated current genetic diversity of TB and rifampicin resistant TB by, Restriction Fragment Length Polymorphism (RFLP) based on fingerprinting of the IS6110 insertion sequence, in the Western province of Sri Lanka, the famous touristic destination with the highest TB burden in the country.
Methodology: Genomic DNA extracted from susceptible and rifampicin resistant TB strains (confirmed for rpoB gene point mutations) were digested with PvuII restriction enzyme, electrophoresed and subjected to Southern transfer. The blots were hybridised with IS6110 probe and visualized using a chemiluminescence detection.
Results: The number of copies of IS6110 per isolate varied from 1 to 14. The dendrogram revealed a total of 68 distinct strains among 77 TB isolates and they belonged to nine clusters. Both rifampicin resistant and susceptible strains were distributed in all clusters. This evaluation revealed the absence of genetically identical or strong relatedness between susceptible and resistant isolates. However, clonal expansion was detected in transmission of both TB and rifampicin resistant TB. In addition, the resistant isolates having the novel mutation had no clonal relatedness.
Conclusion: This is the first observational study regarding clonal expansion of TB in Sri Lanka. Thus, further investigation on genotypes, clonal expansion and transmission of drug resistance using additional markers would be useful for controlling TB.
Prevalence of Salmonella enterica in slaughtered pigs in Serbia: Serotyping, PFGE-genotyping and antimicrobial resistance
Authors: Kureljusic Jasna Mirko , Dmitrić Marko Predrag , Vidanović Dejan Svetislav , Teodorović Vlado Božidar , Kureljušić Branislav Ilija , Velhner Maja Josip , Karabasil Neđeljko Ratko 
Published: September 2017

Introduction: The aim of this study was to determine the prevalence of Salmonella along the slaughter line and to identify possible critical control points in one slaughterhouse facility located in the city of Belgrade.
Methodology: In total, 700 samples were tested: two swabs from both sides of carcass were taken from each of 100 pigs. In this way, 200 pig skin swab samples were taken after stunning, 200 after processing and 200 after chilling. Additional 100 samples of ileal contents were also taken from the same pigs to obtain a collection of 270 isolates. All samples were analyzed using standard culture methods and serotyping. PFGE was performed for 27 isolates. Determination of antimicrobial resistance was performed by E-test.
Results: In total, 47 (23.5%) swab samples were positive for the presence of Salmonella after stunning. After processing, Salmonella was isolated in two swab samples (1%), whereas all samples which were collected after chilling were negative for Salmonella. The sampling of ileal contents was positive for five Salmonella isolates (5%). The most frequently isolated serotypes were S. Derby (90.74%), S. Infantis (5.56%) and S. Typhimurium (3.7%). All tested isolates were resistant to tetracycline. Resistance was recorded to nalidixic acid (23.3%), ciprofloxacin (20%), ampicillin (10%) and chloramphenicol (14.4%), as well. The PFGE results indicated that isolates had a high genetic similarity.
Conclusions: The investigation has confirmed that bacteriological examinations of carcass swabs, as well as ileal content, could be used to assess the carriage of salmonellae in pigs at the time of slaughter.
Influence of Short-Term Study Abroad Experiences on Community Health Baccalaureate Students
Authors: Philips Lynelle , Bloom Tina , Gainey Tammie , Chiocca Ellen 
Published: September 2017

Background:

Very short study abroad programs may be most feasible in undergraduate nursing programs, but little research describes their value for prospective nurses. The narratives of senior baccalaureate nursing students (
N
= 62) who traveled for 2 weeks to Cape Coast, Ghana, between semesters for a faculty-led community health clinical experience were analyzed.

Method:
Students responded to pre- and posttravel semi-structured, open-ended prompts regarding expectations and perceptions of culture, health, and happiness. Data were analyzed using a qualitative descriptive approach.

Results:

Four themes emerged related to perceptions of culture, relationships with community, definitions of health and happiness, and adaptability and innovation. African American students' (
n
= 3) responses highlighted unique themes regarding personal identity.

Conclusion:

Student perceptions of culture demonstrated progression through previously described stages of cultural competence. Relatively novel themes regarding community relationships, perceptions of health and happiness, and adaptability suggest additional value of this short-term study abroad experience for nursing students. [
J Nurs Educ.
2017;56(9):528–533.]
Overview of the optical properties of fluorescent nanoparticles for optical imaging
Authors: Boschi Federico , De Sanctis Francesco 
Published: September 2017

<p>Nanoparticles (NPs) include a wide group of small structures composed by very different materials and characterized by peculiar properties that make them suitable for many applications, especially imaging and drug delivery. In this overview we focus on the optical properties of fluorescent NPs available for <em>in vivo</em>, <em>in vitro</em> and <em>ex vivo</em> preclinical studies and detectable with the optical imaging technique alone or in combination with microscopic confocal imaging. We summarize here the basic principles of the optical detection of fluorescent NPs, elucidate which are the current issues to be resolved and possible solutions to achieve the highest sensitivity and specificity for an unbiased analysis. So far NPs application in clinic is in evaluation due to safety questions still unaddressed but in the future they could dramatically improve both preclinical research and patient clinical care. </p>
Non-Gaussian data assimilation of satellite-based leaf area index observations with an individual-based dynamic global vegetation model
Authors: Arakida Hazuki , Miyoshi Takemasa , Ise Takeshi , Shima Shin-ichiro , Kotsuki Shunji 
Published: September 2017

Abstract. We developed a data assimilation system based on a particle filter approach with the spatially explicit individual-based dynamic global vegetation model (SEIB-DGVM). We first performed an idealized observing system simulation experiment to evaluate the impact of assimilating the leaf area index (LAI) data every 4 days, simulating the satellite-based LAI. Although we assimilated only LAI as a whole, the tree and grass LAIs were estimated separately with high accuracy. Uncertain model parameters and other state variables were also estimated accurately. Therefore, we extended the experiment to the real world using the real Moderate Resolution Imaging Spectroradiometer (MODIS) LAI data and obtained promising results.
Tien jaar Pensioenwet
Authors: Lutjens Erik 
Published: September 2017

Samenvatting
De Pensioenwet is in 2007 in werking getreden. Deze wet geeft regels betreffende het – aanvullend – pensioen in de werkgever-werknemersverhouding. De Pensioenwet beoogt aan werknemers financiële en uitvoeringszekerheid te geven, opdat hun pensioenverwachtingen ook uitkomen. Kort na inwerkingtredingen ontstonden hierin al teleurstellingen van werknemers: de financiële en kredietcrisis sloeg een bres in het vermogen van pensioenfondsen en voor veel rechthebbenden waren kortingen nodig. Dit leidde tot een nu al jaren durend debat over de inrichting van het pensioenstelsel in de toekomst. Tegen die achtergrond geeft dit artikel een overzicht van de juridische aandachtspunten van tien jaar Pensioenwet.
Multi-criteria Optimization of Motorways of the Sea in the Function of the Environment Protection: Case Study of Croatia
Authors: Jugović Alen , Cukrov Marijan , Poletan Jugović Tanja 
Published: September 2017

The transport system causes extremely harmful consequences for society and the environment. It is manifested through the increased emission of harmful exhaust gases, traffic congestions, traffic accidents, increased level of noise, higher levels of stress and various diseases of all participants of the transport system and society in general. The implementation and modernization of intermodality through the Motorways of the Sea (MoS) as its ecological and socio-economic sustainable subsystem is the efficient way of reducing the above mentioned consequences. Further sustainable development of MoS can be observed according to the ecological and socio-economic criteria and sub-criteria set out in this paper in order to keep it in direct function of protecting the society and preserving the environment.
Re-examination of the contribution of substrates to energy expenditure during high-intensity intermittent exercise in endurance athletes
Authors: Aslankeser Zübeyde , Balcı Şükrü Serdar 
Published: September 2017

BackgroundIt has been believed that the contribution of fat oxidation to total energy expenditure is becoming negligible at higher exercise intensities (about 85% VO2max). The aim of the present study was to examine the changes in substrate oxidation during high-intensity interval exercise in young adult men.MethodsA total of 18 healthy well-trained (aged 19.60 ± 0.54 years, BMI = 22.19 ± 0.64 kg/m2,n = 10) and untrained (aged 20.25 ± 0.41 years, BMI = 22.78 ± 0.38 kg/m2,n = 8) young men volunteered to participate in this study. After an overnight fast, subjects were tested on a cycle ergometer and completed six 4-min bouts of cycling (at ∼80% VO2max) with 2 min of rests between intervals. Energy expenditure and the substrate oxidation rate were measured during the experiment by using indirect calorimetry. The blood lactate concentration was collected immediately after each interval workout.ResultsThe fat oxidation rate during each workout was significantly different between the untrained and the athlete groups (p < 0.05), and the carbohydrate (CHO) oxidation rate during the experiment was similar between groups (p > 0.05). Moreover, lactate concentration significantly increased in the untrained group (p < 0.05), whereas it did not significantly change in the athlete group during the workouts (p > 0.05). Fat contribution to energy expenditure was significantly higher in the athlete group (∼25%) than in the untrained group (∼2%).ConclusionsThe present study indicates that 17 times more fat oxidation was measured in the athlete group compared to the untrained group. However, the athletes had the same CHO oxidation rate as the recreationally active subjects during high-intensity intermittent exercise. Higher fat oxidation rate despite the same CHO oxidation rate may be related to higher performance in the trained group.
Divergence of compost extract and bio-organic manure effects on lucerne plant and soil
Authors: Ren Haiyan , Hu Jian , Hu Yifei , Yang Gaowen , Zhang Yingjun 
Published: September 2017

AimApplication of organic materials into agricultural systems enhances plant growth and yields, and improves soil fertility and structure. This study aimed to examine the effects of “compost extract (CE)”, a soil conditioner, and bio-organic manure (BOM) on the growth of lucerne (Medicago sativa), and compare the efficiency between BOM (including numbers of microorganisms) and CE (including no added microorganisms).MethodA greenhouse experiment was conducted with four soil amendment treatments (control, BOM, CE and CEBOM), and was arranged in a completely randomized design with 10 replicates for each treatment. Plant biomass, nutritive value and rhizobia efficacy as well as soil characteristics were monitored.ResultCE rather than BOM application showed a positive effect on plant growth and soil properties when compared with the control. Lucerne nodulation responded equally to CE addition and rhizobium inoculation. CE alone and in combination with BOM significantly increased plant growth and soil microbial activities and improved soil structure. The synergistic effects of CE and BOM indicate that applying CE and BOM together could increase their efficiency, leading to higher economic returns and improved soil health. However, CE alone is more effective for legume growth since nodulation was suppressed by nitrogen input from BOM. CE had a higher efficiency than BOM for enriching soil indigenous microorganisms instead of adding microorganisms and favouring plant nodulation.
Revolution and Evolution: The Architectural Association
Authors: Wright Clare 
Published: September 2017

The Architectural Association conducts its pedagogical alchemy in a labyrinthine terrace of grand Georgian townhouses in London's Bloomsbury. Intimately intertwined with the school's sense of identity, the buildings form a responsive and still‐evolving armature for activities.A new masterplan commissioned from Wright & Wright Architects, currently taking shape, will consolidate the AA as a physical, institutional and cultural entity. Clare Wright, one of the practice's cofounders, explains how.
Morphology of a Ternary Blend Solar Cell Based on Small Molecule:Conjugated Polymer:Fullerene Fabricated by Blade Coating
Authors: Wu Xiaomin , Lan Shuqiong , Zhang Guocheng , Chen Qizhen , Chen Huipeng , Guo Tailiang 
Published: September 2017

AbstractHere, conjugated polymer is added as third component to tune the solution viscosity, morphology, and function of small molecule (SM) based bulk‐heterojunction (BHJ) solar cells, which are fabricated using blade coating. Novel information about the effect of blade coating speed on the nanoscale morphology and function of ternary blend solar cells is provided. The crystal sizes increase with an increase of coating speed for both binary and ternary blends, while the addition of the third component tends to favor smaller SM crystal grains and improves the connectivity of SM crystals. Small angle neutron scattering experiments provide the first clear experimental evidence that the addition of the third component would significantly impact the fullerene phase separation, which is crucial for bimolecular recombination and charge transport. It shows that for both binary and ternary blends, the concentration and sizes of [6,6]‐phenyl‐C61‐butyric acid methyl ester (PCBM) aggregates increase with an increase of coating speed, while addition of third component does not affect the volume fraction of PCBM aggregates but impacts the size of PCBM aggregates. It is demonstrated that the judicious selection of blade coating speed and addition of conjugated polymer optimize the morphology of SM‐BHJ, providing guidelines for high performance SM‐BHJs from roll‐to‐roll production.
Hybrid 3D Printing of Soft Electronics
Authors: Valentine Alexander D. , Busbee Travis A. , Boley John William , Raney Jordan R. , Chortos Alex , Kotikian Arda , Berrigan John Daniel , Durstock Michael F. , Lewis Jennifer A. 
Published: September 2017

AbstractHybrid 3D printing is a new method for producing soft electronics that combines direct ink writing of conductive and dielectric elastomeric materials with automated pick‐and‐place of surface mount electronic components within an integrated additive manufacturing platform. Using this approach, insulating matrix and conductive electrode inks are directly printed in specific layouts. Passive and active electrical components are then integrated to produce the desired electronic circuitry by using an empty nozzle (in vacuum‐on mode) to pick up individual components, place them onto the substrate, and then deposit them (in vacuum‐off mode) in the desired location. The components are then interconnected via printed conductive traces to yield soft electronic devices that may find potential application in wearable electronics, soft robotics, and biomedical devices.
One‐Pot Enantioselective Synthesis of d‐Phenylglycines from Racemic Mandelic Acids, Styrenes, or Biobased l‐Phenylalanine via Cascade Biocatalysis
Authors: Zhou Yi , Wu Shuke , Li Zhi 
Published: September 2017

AbstractEnantiopure d‐phenylglycine and its derivatives are an important group of chiral amino acids with broad applications in thepharmaceutical industry. However, the existing synthetic methods for d‐phenylglycine mainly rely on toxic cyanide chemistry and multistep processes. To provide green and safe alternatives, we envisaged cascade biocatalysis for the one‐pot synthesis of d‐phenylglycine from racemic mandelic acid, styrene, and biobased l‐phenylalanine, respectively. Recombinant Escherichia coli (LZ110) was engineered to coexpress four enzymes to catalyze a 3‐step reaction in one pot, transforming mandelic acid (210 mM) to give enantiopure d‐phenylglycine in 29.5 g L−1 (195 mM) with 93% conversion. Using the same whole‐cell catalyst, twelve other d‐phenylglycine derivatives were also produced from the corresponding mandelic acid derivatives in high conversion (58–94%) and very high ee (93–99%). E. coli (LZ116) expressing seven enzymes was constructed for the transformation of styrene to enantiopure d‐phenylglycine in 80% conversion via a one‐pot 6‐step cascade biotransformation. Twelve substituted d‐phenylglycines were also produced from the corresponding styrene derivatives in high conversion (45–90%) and very high ee (92–99%) via the same cascade reactions. A nine‐enzymeexpressing E. coli (LZ143) was engineered to transform biobased l‐phenylalanine to enantiopure d‐phenylglycine in 83% conversion via a one‐pot 8‐step transformation. Preparative biotransformations were also demonstrated. The high‐yielding synthetic methods use cheap and green reagents (ammonia, glucose, and/or oxygen), and E. coli whole‐cell catalysts, thus providing green and useful alternative methods for manufacturing d‐phenylglycine.magnified image
Targeted next‐generation sequencing in myelodysplastic syndromes and prognostic interaction between mutations and IPSS‐R
Authors: Tefferi Ayalew , Lasho Terra L. , Patnaik Mrinal M. , Saeed Lyla , Mudireddy Mythri , Idossa Dame , Finke Christy , Ketterling Rhett P. , Pardanani Animesh , Gangat Naseema 
Published: September 2017

AbstractA 27‐gene panel was used for next‐generation sequencing (NGS) in 179 patients (median age 73 years) with primary myelodysplastic syndromes (MDS); risk distribution according to the revised International Prognostic Scoring System (IPSS‐R) was 11% very high, 18% high, 17% intermediate, 38% low and 16% very low. At least one mutation/variant was detected in 147 (82%) patients; 23% harbored three or more mutations/variants. The most frequent mutations/variants included ASXL1 (30%), TET2 (25%), SF3B1 (20%), U2AF1 (16%), SRSF2 (16%), TP53 (13%), RUNX1 (11%), and DNMT3A (10%). At a median follow up of 30 months, 148 (83%) deaths and 26 (15%) leukemic transformations were recorded. Multivariable analysis of mutations/variants identified ASXL1 (HR 1.7, 95% CI 1.2‐2.5), SETBP1 (HR 4.1, 95% CI 1.6‐10.2) and TP53 (HR 2.2, 95% CI 1.3‐3.4) as risk factors for overall and SRSF2 (HR 3.9, 95% CI 1.5‐10.2), IDH2 (HR 3.7, 95% CI 1.2‐11.4), and CSF3R (HR 6.0, 95% CI 1.6‐22.6) for leukemia‐free survival. Addition of age to the multivariable model did not affect these results while accounting for IPSS‐R weakened the significance of TP53 mutations/variants (P = .1). An apparently favorable survival impact of SF3B1 mutations was no longer evident after adjustment for IPSS‐R. Approximately 41% and 20% of patients harbored at least one adverse mutation/variant for overall and leukemia‐free survival, respectively. Number of mutations/variants did not provide additional prognostic value. The survival impact of adverse mutations was most evident in IPSS‐R very low/low risk patients. These observations suggest that targeted NGS might assist in treatment decision‐making in lower risk MDS.
Thermal Schrödinger Equation: Efficient Tool for Simulation of Many‐Body Quantum Dynamics at Finite Temperature
Authors: Gelin Maxim F. , Borrelli Raffaele 
Published: September 2017

AbstractWe develop a wave‐function‐based method for the simulation of quantum dynamics of systems with many degrees of freedom at finite temperature. The method is inspired by the ideas of Thermo Field Dynamics (TFD). As TFD, our method is based on the doubling of the system's degrees of freedom and thermal Bogoliubov transformation. As distinct from TFD, our method implements the doubling of thermalized degrees of freedom only, and relies upon the explicitly constructed generalized thermal Bogoliubov transformation, which is not restricted to fermionic and bosonic degrees of freedom. This renders the present approach computationally efficient and applicable to a large variety of systems.