bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reversed patent ductus arteriosus and multiple congenital malformations in an 8‐day‐old Arabo‐Friesian foal
Authors: Dufourni A. , Decloedt A. , De Clercq D. , Saey V. , Chiers K. , van Loon G. 
Published: August 2017

SummaryAn 8‐day‐old Arabo‐Friesian filly was presented with signs of severe dyspnoea, tachypnoea, coughing and cyanotic mucous membranes. On auscultation, a bilateral grade V/VI continuous heart murmur and heart rate of 155 beats/min (sinus tachycardia) were detected. Lung ultrasonography revealed pronounced comet tail artefacts indicating lung oedema. Echocardiography showed right ventricular hypertrophy, a 1.2 cm muscular ventricular septal defect with a left‐to‐right shunt, a stenotic bicuspid pulmonary valve and severe mitral and tricuspid valve regurgitation. Tricuspid regurgitation peak velocity indicated a right ventricular systolic pressure of 119 mmHg. The pulmonary artery was severely dilated and a 1 cm diameter patent ductus arteriosus was found. Colour flow Doppler showed systolic ductal flow reversal with right‐to‐left shunting through the ductus. Arterial partial oxygen pressure and saturation were lower in the metatarsal artery (25 mmHg, saturation 52.6%) than in the carotid artery (31 mmHg, saturation 64.3%). Due to the poor prognosis, the foal was subjected to euthanasia and necropsy confirmed the ultrasonographic findings. Patent ductus arteriosus is a rare condition and occurs most frequently in combination with tetralogy and pentalogy of Fallot. A genetic basis for congenital cardiac disease, especially for ventricular septal defects, in Arabians and for aortic rupture and aorto‐pulmonary fistulation in Friesians has been reported. Whether cross‐breeding leads to an increased prevalence is unknown. This is the first case report with echocardiographic visualisation of reversed ductal flow in a neonatal Arabo‐Friesian foal.
Red clover varieties of Mattenklee type have higher production, protein yield and persistence than Ackerklee types in grass–clover mixtures
Authors: Hoekstra N. J. , De Deyn G. B. , Xu Y. , Prinsen R. , Van Eekeren N. 
Published: August 2017

AbstractDairy farmers have increased interest in multiyear red clover–ryegrass ley pasture swards because of their high productivity and protein concentration but the adoption of such mixtures has been restricted because of poor persistency of many red clover cultivars currently used. We aimed (i) to assess dry‐matter yield (DMY), persistence and nutritive value of four Mattenklee and four Ackerklee cultivars and (ii) to investigate the underlying plant morphological traits. We conducted a 4‐year field experiment with red clover–ryegrass mixtures, in combination with a short‐term pot experiment in which the red clover cultivars were grown both in monoculture and in mixture with Lolium perenne L. In the field, Mattenklees showed higher production (on average 42% higher) and clover content (on average 34% higher) in the third and fourth year of production compared to Ackerklees. In the fourth year, Mattenklees had slightly lower digestibility and lower protein concentration compared to Ackerklees cultivars; however, the digestible DMY and the protein yield were higher for Mattenklees. Both persistence and nutritive value of the different red clover cultivars were closely correlated with plant morphological traits. For stem length, there was close correlation (r > .77) between the results from the pot experiment and the field experiment, suggesting that stem length may be an important trait for plant breeding.
After globalisation: A reconceptualisation of transnational Higher Education governance in Singapore and Hong Kong
Authors: Lo William Yat Wai 
Published: August 2017

AbstractResearch on transnational Higher Education governance has provided a thesis explaining how East Asian states have successfully selectively blended elements of globalisation in Higher Education with their pre‐existing regulatory regimes. However, this paper argues that the thesis overlooks the significance of local politics in understanding the formulation of Higher Education policy, thus insufficiently acknowledging the indeterminacy that arises in the globalisation process. To address this argument, this paper examines the transnational Higher Education development in Singapore and Hong Kong and explains how political resistance and corresponding policy changes that emerged in these two societies help reconceptualise transnational Higher Education governance.
Interrogating the Relationship between Remigration and Sustainable Return
Authors: Kuschminder Katie 
Published: August 2017

AbstractAssisted voluntary return is a central component of many countries managed migration policies. Within these programmes achieving a sustainable return is a common policy goal, which is often measured through remigration. In this paper, it is argued that remigration is not a valid indicator to measure sustainable return. A new definition and approach to defining and measuring sustainable return is presented based on a multidimensional return and reintegration index, which is tested with a sample of 118 returnees in six countries. Due to small sample size a chi‐square test is used to examine the correlation between the return and reintegration index and remigration intentions. The results demonstrate the relationship between having a concrete remigration plan and the return and reintegration index is insignificant. This relationship between remigration and sustainable return is further interrogated throughout the paper.
Swiss S1 guideline for the treatment of rosacea
Authors: Anzengruber F. , Czernielewski J. , Conrad C. , Feldmeyer L. , Yawalkar N. , Häusermann P. , Cozzio A. , Mainetti C. , Goldblum D. , Läuchli S. , Imhof L. , Brand C. , Laffitte E. , Navarini A.A. 
Published: August 2017

AbstractRosacea (in German sometimes called ‘Kupferfinne’, in French ‘Couperose’ and in Italian ‘Copparosa’) is a chronic and frequently relapsing inflammatory skin disease primarily affecting the central areas of the face. Its geographic prevalence varies from 1% to 22%. The differential diagnosis is wide, and the treatment is sometimes difficult and varies by stage of rosacea. For erythematous lesions and telangiectasia, intense pulsed light (IPL) therapy and lasers are popular treatment option. In addition, a vasoconstrictor agent, brimonidine, has recently been developed. For papulopustular rosacea, topical antibiotics, topical and systemic retinoids, as well as systemic antibiotics are used. A topical acaricidal agent, ivermectin, has undergone clinical development and is now on the market. In the later stages, hyperplasia of the sebaceous glands develops, resulting in phymatous growths such as the frequently observed bulbous nose or rhinophyma. Ablative laser treatments have largely replaced classical abrasive tools. Here, we reviewed the current evidence on the treatment of rosacea, provide a guideline (S1 level) and discuss the differential diagnosis of rosacea.
New Perspectives on an Old Issue: A Comparative MS‐CASPT2 and OM2‐MRCI Study of Polyenes and Protonated Schiff Bases
Authors: Dokukina Irina , Marian Christel M. , Weingart Oliver 
Published: August 2017

AbstractPolyenic systems are involved in light perception of numerous living organisms. Although a π‐conjugated backbone is a common feature of all polyenes, their photophysics may vary. We provide a comparative quantum mechanical study of low‐lying S1 and S2 excited states in short (3‐5 double bonds) symmetric all‐trans linear polyenes and corresponding protonated Schiff bases. In our investigation, we use the well‐established ab initio multireference CASPT2 approach and benchmark the efficient semiempirical OM2‐MRCI approach against it. For all protonated Schiff bases, MS‐CASPT2 results in two distinct S1 minima with inverted and noninverted bond length pattern, respectively. We find that OM2‐MRCI is a computationally affordable and reliable alternative to MS‐CASPT2 for investigations of polyenic systems, particularly when highly demanding calculations (e.g. excited‐state dynamics) need to be performed.
Eradication of invasive Carpobrotus sp.: effects on soil and vegetation
Authors: Chenot Julie , Affre Laurence , Gros Raphael , Dubois Laura , Malecki Sarah , Passetti Aurélie , Aboucaya Annie , Buisson Elise 
Published: August 2017

AbstractInvasive species management (eradication or control) can be used to promote native plant restoration. The objective of this study is to evaluate different treatments to guide the selection of future modalities for the eradication (i.e. elimination of all individuals in a population) of Carpobrotus sp. from a strict nature reserve. Two removal methods were tested: (1) living Carpobrotus removal; (2) living Carpobrotus and litter removal. To assess the effectiveness of each treatment, we studied the recolonization of native vegetation, the recolonization of Carpobrotus, and soil erosion and compared these metrics to those taken in native vegetation and in patches of intact Carpobrotus. We also tested the capacity of a 50‐cm‐wide Carpobrotus strip to retain soil. The removal of Carpobrotus together with its litter led to high rates of soil erosion. The Carpobrotus strips were found to retain the soil rather well. Removing live Carpobrotus while leaving its litter in place reduced soil erosion and led to higher native plant species recolonization. The composition of the vegetation 10 months after applying the treatments was biased in favor of native pioneer species. These are typically the first species to establish (Aetheoriza bulbosa and Arisarum vulgare resprouted, Frankenia hirsuta and Lotus cytisoides germinated, and Sonchus sp. benefited from long‐distance dispersal). Few weedy species were recorded (e.g. Sonchus asper asper). Whatever the treatment, the risk of reinvasion from the seed bank or from resprouting stems is nonnegligible, so long‐term monitoring is vital to the ultimate success of the eradication program.
A theory of participation: what makes stakeholder and public engagement in environmental management work?
Authors: Reed Mark S. , Vella Steven , Challies Edward , de Vente Joris , Frewer Lynne , Hohenwallner‐Ries Daniela , Huber Tobias , Neumann Rosmarie K. , Oughton Elizabeth A. , Sidoli del Ceno Julian , van Delden Hedwig 
Published: August 2017

AbstractThis article differentiates between descriptive and explanatory factors to develop a typology and a theory of stakeholder and public engagement. The typology describes different types of public and stakeholder engagement, and the theory comprises four factors that explain much of the variation in outcomes (for the natural environment and/or for participants) between different types of engagement. First, we use a narrative literature search to develop a new typology of stakeholder and public engagement based on agency (who initiates and leads engagement) and mode of engagement (from communication to coproduction). We then propose a theory to explain the variation in outcomes from different types of engagement: (1) a number of socioeconomic, cultural, and institutional contextual factors influence the outcomes of engagement; (2) there are a number of process design factors that can increase the likelihood that engagement leads to desired outcomes, across a wide range of sociocultural, political, economic, and biophysical contexts; (3) the effectiveness of engagement is significantly influenced by power dynamics, the values of participants, and their epistemologies, that is, the way they construct knowledge and which types of knowledge they consider valid; and (4) engagement processes work differently and can lead to different outcomes when they operate over different spatial and temporal scales. We use the theoretical framework to provide practical guidance for those designing engagement processes, arguing that a theoretically informed approach to stakeholder and public engagement has the potential to markedly improve the outcomes of environmental decision‐making processes.
Palatal perforation and chemical ulcers of the tongue in a blind patient
Authors: Pinheiro Tiago Novaes , Fayad Flavio , Júnior Luiz Roberto Magalhães , Nichthauser Brigitte , Braga Francisco , Passos Shirley Maria 
Published: August 2017

ABSTRACTWe report a unique case of a potassium aluminum sulfate oral dissolution leading to palatal chemical necrosis and extensive chemical ulcers on the tongue. The patient, a 47‐year‐old white, blind male, denied using cocaine or other illegal drugs that could cause such lesions. His self‐medication started as a treatment for a traumatic ulcerative lesion on the hard palate. After palatal perforation, he started another self‐medication routine, mixing corticoid cream and tandrilax tablets with a gauze obturator. Our treatment comprised the removal of all chemical factors, a surgical debridement, and a prosthetic obturator to resolve the communication. The 1‐year follow‐up showed no complications.
Confidence Intervals for the Current Status Model
Authors: Groeneboom Piet , Hendrickx Kim 
Published: August 2017

AbstractWe discuss a new way of constructing pointwise confidence intervals for the distribution function in the current status model. The confidence intervals are based on the smoothed maximum likelihood estimator, using local smooth functional theory and normal limit distributions. Bootstrap methods for constructing these intervals are considered. Other methods to construct confidence intervals, using the non‐standard limit distribution of the (restricted) maximum likelihood estimator, are compared with our approach via simulations and real data applications.
Depression Mediates the Relationship Between Distress Tolerance and Nonsuicidal Self‐Injury Among Adolescents: One‐Year Follow‐Up
Authors: Lin Min‐Pei , You Jianing , Wu Yung Wei , Jiang Yongqiang 
Published: August 2017

Through a one‐year follow‐up design, this study examined whether distress tolerance would increase the risk for nonsuicidal self‐injury (NSSI), mediated through depression in a representative sample of adolescents. Participants (N = 2,170) were recruited from senior high schools throughout Taiwan using both stratified and cluster sampling in time 1 (T1), and 1,832 students were followed‐up one year later (T2). Structure equation modeling results revealed that after controlling NSSI measured at T1, NSSI (T2) was significantly predicted by distress tolerance (T1) and fully mediated through depression (T2). The mediating role of depression in the relationship between distress tolerance and NSSI are discussed.
Media Narratives Versus Evidence in Economic Policy Making: The 2008–2009 Financial Crisis*
Authors: McBeth Mark K. , Tokle Robert J. , Schaefer Susan 
Published: August 2017

ObjectiveEconomic policy in late 2008 and through 2009 led to unprecedented media coverage and debate. This debate played out on the 24‐hour news cycle of cable news networks. Traditionally, media has been viewed as merely reporting the news, but today evidence suggests that the media is an active player for or against certain policies. This study asks: “How did the three major cable news networks cover the economic crisis of 2008–2009 and how did this coverage converge or diverge from the impacts that economists thought these policies actually had on the economy?”MethodsWe content analyzed 50 news transcripts each from Fox News, CNN, and MSNBC.ResultsWe found that MSNBC primarily constructed Democratic Party officials and their allies as heroes (fixers of the problem), and that Fox News primarily constructed Democratic Party officials and their allies as villains (the cause of the problem). Fox News when discussing the economic policies constructed more costs (victims) than benefits (beneficiaries), whereas both MSNBC and CNN constructed more benefits (beneficiaries) than costs (victims). Overall, MSNBC was the most pro‐Democratic Party in its narratives, with Fox News the most pro‐Republican Party, and CNN leaning Democratic but also mixed in its narratives. Nonpartisan economic analyses showed that despite the pessimistic narratives about financial reform found in Fox News, the economic policies had a positive impact on the economy.ConclusionsThis study concludes with an analysis of the potential impact of media coverage on U.S. public policy making as a new U.S. president takes office.
A vascularized preputial free flap for labial reconstruction in a dog
Authors: Liu Chi‐Hsin , Yeh Lih‐Seng 
Published: August 2017

AbstractObjectiveTo describe the clinical application of a vascularized preputial free flap in the reconstruction of a large facial‐labial defect.Study designCase report.AnimalsAn adult neutered male mongrel dog with a large left facial‐labial defect.MethodsA preputial free flap was created by elevating the cranial part of the prepuce, using the ipsilateral caudal superficial epigastric vessels as a vascular pedicle. The flap was transferred to the facial‐labial defect and the donor vessels anastomosed to the sublingual artery and vein, using standard microvascular technique.ResultsThe free flap survived, leading to good cosmetic and functional outcomes. No major complications were encountered at either the donor or recipient sites after 2 years of follow‐up.ConclusionVascularized preputial free flaps can be used to manage composite facial and oral cavity defects involving large areas of skin and mucosa.
Volume loading augments cutaneous vasodilatation and cardiac output of heat stressed older adults
Authors: Gagnon Daniel , Romero Steven A. , Ngo Hai , Sarma Satyam , Cornwell William K. , Poh Paula Y. S. , Stoller Douglas , Levine Benjamin D. , Crandall Craig G. 
Published: August 2017

Key points
Age‐related changes in cutaneous microvascular and cardiac functions limit the extent of cutaneous vasodilatation and the increase in cardiac output that healthy older adults can achieve during passive heat stress.
However, it is unclear if these age‐related changes in microvascular and cardiac functions maximally restrain the levels of cutaneous vasodilatation and cardiac output that healthy older adults can achieve during heat stress.
We observed that rapid volume loading, performed during passive heat stress, augments both cutaneous vasodilatation and cardiac output in healthy older humans.
These findings demonstrate that the microcirculation of healthy aged skin can further dilate during passive heat exposure, despite peripheral limitations to vasodilatation.
Furthermore, healthy older humans can augment cardiac output when cardiac pre‐load is increased during heat stress.
AbstractPrimary ageing markedly attenuates cutaneous vasodilatation and the increase in cardiac output during passive heating. However, it remains unclear if these responses are maximally restrained by age‐related changes in cutaneous microvascular and cardiac functions. We hypothesized that rapid volume loading performed during heat stress would increase cardiac output in older adults without parallel increases in cutaneous vasodilatation. Twelve young (Y: 26 ± 5 years) and ten older (O: 69 ± 3 years) healthy adults were passively heated until core temperature increased by 1.5°C. Cardiac output (thermodilution), forearm vascular conductance (FVC, venous occlusion plethysmography) and cutaneous vascular conductance (CVC, laser‐Doppler) were measured before and after rapid infusion of warmed saline (15 mL kg−1, ∼7 min). While heat stressed, but prior to saline infusion, cardiac output (O: 6.8 ± 0.4 vs. Y: 9.4 ± 0.6 L min−1), FVC (O: 0.08 ± 0.01 vs. Y: 0.17 ± 0.02 mL (100 mL min−1 mmHg−1)−1), and CVC (O: 1.29 ± 0.34 vs. Y: 1.93 ± 0.30 units mmHg−1) were lower in older adults (all P < 0.01). Rapid saline infusion increased cardiac output (O: +1.9 ± 0.3, Y: +1.8 ± 0.7 L min−1), FVC (O: +0.015 ± 0.007, Y: +0.048 ± 0.013 mL (100 mL min−1 mmHg−1)−1), and CVC (O: +0.28 ± 0.10, Y: +0.29 ± 0.16 units mmHg−1) in both groups (all P < 0.01). The absolute increase in cardiac output and CVC were similar between groups, whereas FVC increased to a greater extent in young adults (P < 0.01). These results demonstrate that healthy older adults can achieve greater levels of cutaneous vasodilatation and cardiac output during passive heating.
Safety and feasibility of transcranial direct current stimulation (tDCS) combined with sensorimotor retraining in chronic low back pain: a protocol for a pilot randomised controlled trial
Authors: Ouellette Adam Louis , Liston Matthew B , Chang Wei-Ju , Walton David M , Wand Benedict Martin , Schabrun Siobhan M 
Published: August 2017

IntroductionChronic low back pain (LBP) is a common and costly health problem yet current treatments demonstrate at best, small effects. The concurrent application of treatments with synergistic clinical and mechanistic effects may improve outcomes in chronic LBP. This pilot trial aims to (1) determine the feasibility, safety and perceived patient response to a combined transcranial direct current stimulation (tDCS) and sensorimotor retraining intervention in chronic LBP and (2) provide data to support a sample size calculation for a fully powered trial should trends of effectiveness be present.Methods and analysisA pilot randomised, assessor and participant-blind, sham-controlled trial will be conducted. Eighty participants with chronic LBP will be randomly allocated to receive either (1) active tDCS + sensorimotor retraining or (2) sham tDCS + sensorimotor retraining. tDCS (active or sham) will be applied to the primary motor cortex for 20 min immediately prior to 60 min of supervised sensorimotor retraining twice per week for 10 weeks. Participants in both groups will complete home exercises three times per week. Feasibility, safety, pain, disability and pain system function will be assessed immediately before and after the 10-week intervention. Analysis of feasibility and safety will be performed using descriptive statistics. Statistical analyses will be conducted based on intention-to-treat and per protocol and will be used to determine trends for effectiveness.Ethics and disseminationEthical approval has been gained from the institutional human research ethics committee (H10184). Written informed consent will be provided by all participants. Results from this pilot study will be submitted for publication in peer-reviewed journals.Trial registration numberACTRN12616000624482