bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship Between Personality and Neurocognition Among the American Elderly: An Epidemiologic Study
Authors: Maldonato Nelson Mauro , Sperandeo Raffaele , Dell'Orco Silvia , Cozzolino Pasquale , Fusco Maria Luigia , Iorio Vittoria Silviana , Albesi Daniela , Marone Patrizia , Nascivera Nicole , Cipresso Pietro 
Published: November 2017

Background:Although different personality traits have often been associated with different levels of mental activity and cognitive functioning, no previous studies have evaluated the association in a sample that mirrors a nationally-representative sample of elderly individuals.Objective:To evaluate the association between personality traits and neurocognitive functioning among individuals 51 years and older using the Cognition and Aging in the USA (CogUSA) database.Methods:We analyzed the association between personality traits and neurocognitive scores derived from Waves I and II of the study. Neurocognitive functions were modeled as an outcome variable using the Big Five Personality Traits as predictors.Results:All personality traits were associated with higher education except Conscientiousness. Older age was associated with higher levels of the Agreeableness and Openness traits. Extraversion, Conscientiousness and Openness were positively associated with increased neurocognitive function and self-rated present memory. Extraversion and Openness also had a positive association with long-term retrieval. Agreeableness was negatively associated with several neurocognitive functions, while Neuroticism was negatively associated with memory and cognitive effort.Conclusion:Extraversion, Conscientiousness and Openness personality traits are associated with good cognitive health. Individuals scoring high in Neuroticism and Agreeableness might benefit from tailored cognitive interventions to prevent age-related cognitive decline.
Desvinculación de los estudios universitarios. Estudio comparativo de indicadores socioeconómicos
Authors: Rodríguez-Ayan María-Noel , Amaya Alejandro , Sotelo Maria-Eugenia 
Published: November 2017

En este trabajo se analizan comparativamente ciertos logros asociados al bienestar socioeconómico de estudiantes que abandonaron el sistema universitario con los logros de egresados universitarios, egresados de otros estudios terciarios y egresados de educación media. Se plantea la hipótesis de que el pasaje incompleto por la universidad puede brindar herramientas para un mejor posicionamiento socioeconómico respecto al de quienes no tienen estudios universitarios, aunque tal posicionamiento no alcance al de un egresado universitario. Los logros concebidos como indicadores de bienestar socioeconómico fueron la existencia de hacinamiento en el hogar, la posesión de determinados elementos de confort, los ingresos mensuales y la tenencia de vivienda. Se utilizó el Análisis de correspondencias múltiples (ACM) para determinar si las variables de elementos de confort conformaban una dimensión, ANOVA para estudiar la variación del confort medio y de los ingresos medios entre las categorías de estudios y el test Z de comparación de proporciones para examinar la relación entre categoría de estudios y género. Los resultados fueron consistentes con la hipótesis planteada.
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibitors and Incident Type 2 Diabetes: A Systematic Review and Meta-analysis With Over 96,000 Patient-Years
Authors: de Carvalho Luiz Sérgio F. , Campos Alessandra M. , Sposito Andrei C. 
Published: November 2017

OBJECTIVE
Like mutations with loss of function in the proprotein convertase subtilisin/kexin type 9 (PCSK9) gene, inhibitors of PCSK9 (PCSK9i) may potentially favor the manifestation of diabetes.

RESEARCH DESIGN AND METHODS
A meta-analysis of phase 2/3 randomized clinical trials (RCTs) assessed PCSK9i versus placebo in the primary hypercholesterolemia setting. Statins and ezetimibe were used in 98.4% of these studies and balanced between PCSK9i and placebo. We calculated relative risks (RRs) and 95% CIs using random- and fixed-effect models.

RESULTS
We included 68,123 participants (20 RCTs) with median follow-up of 78 weeks. PCSK9i increased fasting blood glucose (weighted mean difference 1.88 mg/dL [95% CI 0.91–2.68]; I2 = 0%; P &lt; 0.001) and HbA1c (0.032% [0.011–0.050]; I2 = 15.5%; P &lt; 0.001) when compared with placebo. This effect was not sufficient to increase incidence of diabetes (RR 1.04 [0.96–1.13]; I2 = 0%; P = 0.427). Exploratory meta-regression analyses indicated an association between the increased risk of diabetes and the potency (P = 0.029) and duration (P = 0.026) of PCSK9i treatment.

CONCLUSIONS
In the short term, PCSK9i therapy favors a small but significant increase in plasma glycemia and HbA1c.
Ensayo de tracción según norma DIN 53455
Authors: Berón Zea (traductor) Ricardo 
Published: November 2017

Según norma, el ensayo de tracción sirve para evaluar el comportamiento de los materiales plásticos sometidos a esfuerzo uniaxial de tracción. La traducción de la norma se hizó para beneficio de la industria colombiana con fines no comerciales.
Effects of intravenous administration of lidocaine and buprenorphine on gastrointestinal tract motility and signs of pain in New Zealand White rabbits after ovariohysterectomy
Authors: Schnellbacher Rodney W. , Divers Stephen J. , Comolli Jessica R. , Beaufrère Hugues , Maglaras Christina H. , Andrade Natalia , Barbur Laura A. , Rosselli Desiree D. , Stejskal Marko , Barletta Michele , Mayer Jörg , Rodriguez Paula , Quandt Jane E. 
Published: November 2017

Abstract
OBJECTIVE To compare analgesic and gastrointestinal effects of lidocaine and buprenorphine administered to rabbits undergoing ovariohysterectomy.
ANIMALS Fourteen 12-month-old female New Zealand White rabbits.
PROCEDURES Rabbits were assigned to 2 treatment groups (7 rabbits/group). One group received buprenorphine (0.06 mg/kg, IV, q 8 h for 2 days), and the other received lidocaine (continuous rate infusion [CRI] at 100 μg/kg/min for 2 days). Variables, including food and water consumption, fecal output, glucose and cortisol concentrations, and behaviors while in exercise pens, were recorded.
RESULTS Rabbits receiving a lidocaine CRI had significantly higher gastrointestinal motility, food intake, and fecal output and significantly lower glucose concentrations, compared with results for rabbits receiving buprenorphine. Rabbits receiving lidocaine also had a higher number of normal behaviors (eg, sprawling, traveling, and frolicking) after surgery, compared with behaviors such as crouching and sitting that were seen more commonly in rabbits receiving buprenorphine. Both groups had significant weight loss after surgery. Pain scores did not differ significantly between treatment groups. Significant decreases in heart rate and respiratory rate were observed on the day of surgery, compared with values before and after surgery. Rabbits in the lidocaine group had significantly overall lower heart rates than did rabbits in the buprenorphine group.
CONCLUSIONS AND CLINICAL RELEVANCE A CRI of lidocaine to rabbits provided better postoperative outcomes with respect to fecal output, food intake, and glucose concentrations. Thus, lidocaine appeared to be a suitable alternative to buprenorphine for alleviating postoperative pain with minimal risk of anorexia and gastrointestinal ileus.
Pharmacokinetics of ampicillin-sulbactam in serum and synovial fluid samples following regional intravenous perfusion in the distal portion of a hind limb of adult cattle
Authors: Depenbrock Sarah M. , Simpson Katharine M. , Niehaus Andrew J. , Lakritz Jeffrey , Papich Mark G. 
Published: November 2017

Abstract
OBJECTIVE To describe concentration-over-time data for ampicillin and sulbactam in the digital and systemic circulations and synovial fluid (SYN) of cattle following a single injection of ampicillin-sulbactam as a regional IV perfusion (RIVP).
ANIMALS 6 healthy adult nonlactating Jersey-crossbred cows.
PROCEDURES The right hind limb of each cow was aseptically prepared. A tourniquet was applied around the midmetatarsal region, and 1.0 g of ampicillin with 0.5 g of sulbactam in a combined formulation was administered as an RIVP into the dorsal common digital vein (DCDV). Blood samples from the DCDV and jugular vein and SYN samples from the metatarsophalangeal joint of the prepared limb were collected immediately before and at predetermined times for 24 hours after RIVP. One blood sample was obtained from the abaxial proper plantar vein of the lateral digit of the prepared limb 0.25 hours after RIVP. Serum and SYN ampicillin and sulbactam concentrations were determined by high-performance liquid chromatography.
RESULTS Mean ± SD maximum concentration of ampicillin in SYN and serum obtained from the abaxial proper plantar and jugular veins was 1,995 ± 1,011 μg/mL, 5,422 ± 1,953 μg/mL, and 2.5 ± 1.6 μg/mL, respectively. Corresponding serum and SYN concentrations of sulbactam were lower but followed the same pattern over time as those for ampicillin. Synovial fluid ampicillin concentration remained above 8 μg/mL for a mean time of 18.9 hours.
CONCLUSIONS AND CLINICAL RELEVANCE Potentially therapeutic concentrations of ampicillin were achieved in regional serum and SYN samples; SYN concentrations remained at potentially therapeutic values for > 12 hours following RIVP of 1.5 g of ampicillin-sulbactam in the hind limb of healthy cows.
In vivo evaluation of effects of sedation on results of acoustoelastography of the superficial digital flexor tendons in clinically normal horses
Authors: De Gasperi Diego , Dzierzak Samantha L. , Muir Peter , Vanderby Ray , Brounts Sabrina H. 
Published: November 2017

Abstract
OBJECTIVE To assess the effects of sedation on results of acoustoelastography of the superficial digital flexor tendons (SDFTs) in clinically normal horses.
ANIMALS 27 clinically normal horses.
PROCEDURES For each horse, the pathology index (PI) for the SDFT of each thoracic limb was determined by use of acoustoelastography at 4 locations (5, 10, 15, and 20 cm distal to the accessory carpal bone). Horses were evaluated before and after they were sedated with a combination of detomidine hydrochloride (0.01 mg/kg, IV) and butorphanol tartrate (0.01 mg/kg, IV). A repeated-measures ANOVA was used for statistical analysis.
RESULTS Overall, the PI was lower after sedation than before sedation. In addition, the PI was lower at more distal locations than at more proximal locations. There was not a significant effect of limb (left or right). Differences among individual horses accounted for the largest variance effect.
CONCLUSIONS AND CLINICAL RELEVANCE Sedation with detomidine and butorphanol facilitated acoustoelastography; however, it decreased the SDFT PI in clinically normal horses and should be used consistently in prospective studies. Variance associated with each individual horse in the sample population had the greatest effect on the PI.
The Determing Activation Energy of Total Oxidation Reaction of m-xylene over La0,7Sr0,3BO3 (B = Mn, Fe, Ni) Perovskite Catalysts
Authors: Huyen Tran Thi Thu , Luyen Tran Thi , Mai Nguyen Thi Tuyet 
Published: November 2017

Perovskite-type oxides containing rare earth ions and transition metals are of interest for catalytic oxidation and reduction reactions associated with automotive exhaust emission control. They are known to exhibit a good catalytic activity in the total oxidation reaction of carbon monoxide or hydrocarbon and removal of nitrogen oxides. By partially substitution of A and B ions of the perovskite with others, a wide variety of mixed oxides A1-xA’xB1-yB’yO3 can be obtained, allowing the systematic modification of the catalytic properties. We presented the preparation and the catalytic properties of and La0.7Sr0.3BO3 (B = Mn, Fe, Ni) perovskites in total oxidation of m-xylene in previous report. Obtained results showed that they exhibit a good catalytic activity in total oxidation of m-xylene at relatively low reaction temperature. In present work, the activation energy of total oxidation reaction of m-xylene over these catalysts are determined. The results show that the activation energy of studied catalyst is ranging about from 11.5 to 13.4 kcal/mol. The replacement of Mn by Fe and Ni in La0.7Sr0.3MnO3 perovskite catalyst reduces the catalytic property of La0.7Sr0.3MnO3 catalyst and increases the activation energy of the total oxidation reaction of m-xylene.
Influence of Hydrotalcite Containing Corrosion Inhibitormodified by Silane on Corrosion Protection Performance of Epoxy Coating
Authors: Anh Nguyen Tuan , Hoa Ngo Thi , Hang To Thi Xuan , Duong Nguyen Thuy , Truc Trinh Anh 
Published: November 2017

Abstract:
Zinc aluminum hydrotalcite containing 2-benzothiazolythio-succinic acid (HT-BTSA) and modified by 2-aminoethyl-3-aminopropyltrimethoxysilane (APS) at different concentrations (3%, 5% and 10%). APS modified HT-BTSA (HT-BTSA-S) was incorporated in epoxy coatings at 3% concentration. The corrosion protective performance of the epoxy coatings containing HT-BTSA-S were evaluated by electrochemical impedance spectroscopy, adhesion measurement. The results showed that the presence of HT-BTSA-S improved protection performance of epoxy coating and the best protection was obtained with HT-BTSA modified with 5 % APS.
Current status of Harmful Termites (Isoptera) in Hoi An Ancient Town and Effectiveness of Control of Main Harmful Coptotermes with Bait BDM 10
Authors: Huy Nguyen Quoc 
Published: November 2017

The results of investigations and assessments about termites damagging 178 buildings in the Hoi An ancient town identified 6 species of 2 genera and 2 families. In which, Coptotermes was dominant genus with 4 species, and Cryptotermes had 2 species. There were 102/178 investigated buildings being invaded by termites with various levels. There were 4 species identified as major pests for the Hoi An ancient town. The most dangerous termite species for building was Coptotermes gestroi, followed by Coptotermes formosanus, C. ceylonicus and Cryptotermes domesticus. 77 works which were invaded by Coptotermes had been treated with BDM10 bait. The results showed that the efficiency of termite treatment reached 100% in all of works, in which: 78.11% of the works had achieved the control effect just for the first treatmen; 19,39% of the works needed to be treated for the second time and only 2.5% of the works that were severely damaged, needed the third time for control with bait.
Publicly Manifested—Fatefully Determined—Invariably “Discreet”: The Assessment of Sexuality-Based Asylum Claims in Germany and France
Authors: Wessels Janna 
Published: November 2017

One of the most controversial issues concerning sexuality-based asylum claims in recent years has been “discretion” reasoning—the notion that a claimant can avoid persecution by behaving “discreetly.” Though often challenged, such reasoning has remained resilient in the English-speaking common law jurisdictions, upon which research has mainly focused to date. This article broadens the debate by undertaking a detailed exploration of “discretion” reasoning in sexuality-based asylum claims in Germany and France, two of the major European civil law jurisdictions. In the first part, the article demonstrates that in very different forms “discretion” logics have traditionally also affected sexuality-based asylum claims in each of these jurisdictions. The second part of the article explores the effects that the Europeanization of asylum and the rejections of the “discretion” requirement by the UK Supreme Court in 2010 and the Court of Justice of the European Union in 2012 and 2013 have had on established French and German jurisprudence. The analysis reveals that rather than ending “discretion” reasoning in Germany and France, these developments have transformed it, such that it persists in a different shape. Much like in the common law jurisdictions, with all of its problematic implications, “discretion” reasoning remains deeply entrenched and resistant in German and French decision-making practice concerning sexuality-based asylum claims.
CAx-Prozesskette für komplexe Rotationsbauteile
Authors: Königs Michael , Huwer Tobias , Dax Paul 
Published: November 2017

Kurzfassung
Die spanende Fertigung komplexer Rotationsbauteile ist sehr aufwändig, weswegen die Geometrien häufig auf Kosten der Effizienz vereinfacht werden. Erst durch den Einsatz von Sonderbearbeitungszentren und -werkzeugen ist eine Fertigung der komplexen Geometrien realisierbar. Es entstehen allerdings hohe Kosten für die Herstellung der Sonderwerkzeuge. Ziel des Vorhabens „OpToRoMill“ war die Entwicklung einer CAx-Prozesskette, welche die Fertigung mit herkömmlichen Vollhartmetallfräsern ermöglicht.
Asymptotic formulae for the risk of failure related to an elasto-plastic problem with noise
Authors: Feau Cyril , Laurière Mathieu , Mertz Laurent 
Published: November 2017

The risk of failure of mechanical structures under random forcing is an important concern in earthquake engineering. For a class of simple structures that can be modeled by an elasto-plastic oscillator, the risk of failure can be expressed in terms of the probability that, on a certain interval of time, the plastic deformation goes beyond a threshold related to a failure zone. In this note, asymptotic formulae for the risk of failure of an elasto-perfectly-plastic oscillator excited by a white noise are proposed. Our approach exploits the long cycle (repeating pattern) property of the aforementioned oscillator as introduced in A. Bensoussan, L. Mertz, S.C.P. Yam, Long cycle behaviour of the plastic deformation of an elasto-perfectly-plastic oscillator with noise, C. R. Acad. Sci. Paris Ser. I, 2012. We show that asymptotically the plastic deformation behaves like a Wiener process for which analytical formulae are available. Our result is a consequence of the Anscombe–Donsker Invariance Principle. Numerical experiments and comments are carried out.
Imaging Response of Antiangiogenic and Immune-Oncology Drugs in Metastatic Renal Cell Carcinoma (mRCC): Current Status and Future Challenges
Authors: Fournier Laure , Bellucci Alexandre , Vano Yann , Bouaboula Mehdi , Thibault Constance , Elaidi Reza , Oudard Stephane , Cuenod Charles 
Published: November 2017

This report aims to review criteria which have been proposed for treatment evaluation in mRCC under anti-angiogenic and immune-oncologic therapies and discuss future challenges for imagers. RECIST criteria seem to only partially reflect the clinical benefit derived from anti-angiogenic drugs in mRCC. New methods of analysis propose to better evaluate response to these drugs, including a new threshold for size criteria (–10%), attenuation (Choi and modified Choi criteria), functional imaging techniques (perfusion CT, ultrasound or MRI), and new PET radiotracers. Imaging of progression is one of the main future challenges facing imagers. It is progression and not response that will trigger changes in therapy, therefore it is tumour progression that should be identified by imaging techniques to guide the oncologist on the most appropriate time to change therapy. Yet little is known on dynamics of tumour progression, and much data still needs to be accrued to understand it. Finally, as immunotherapies develop, flare or pseudo-progression phenomena are observed. Studies need to be performed to determine whether imaging can distinguish between patients undergoing pseudo-progression for which therapy should be continued, or true progression for which the treatment must be changed.
Tissue Expression of Erythropoietin Predicts Survival Rates in Clear Cell Renal Cell Carcinoma
Authors: Ferreira Daniel Beltrame , da Costa Walter Henriques , Clavijo Diego Abreu , Decia Ricardo , Cunha Isabela Werneck , Schultz Luciana , Rocha Rafael Malagoli , Guimarães Gustavo Cardoso , Zequi Stênio de Cássio 
Published: November 2017

Objective: To evaluate immunohistochemical erythropoietin (EPO) expression in clear cell renal cell carcinoma (ccRCC), its association with major clinicopathological variables and its prognostic impact. Methods: A total of 220 patients with renal cell carcinoma (RCC) surgically treated between 1989 and 2009 were evaluated in this multi-institutional study. All the cases were reviewed by a single pathologist and the immunohistochemical reactivity to EPO was analysed using tissue microarray. Results: A total of 176 patients with ccRCC were considered, with an average of 48 months of follow-up. Of the tumours evaluated, 47 (26.7%) were negative for EPO expression, and 129 (73.3%) were positive. EPO expression was associated with incidental tumour ( p = 0.016), tumour size ( p = 0.015), Karnofsky Performance Score (KPS) ( p = 0.016), blood transfusion ( p = 0.009) and adrenal involvement ( p = 0.038). The median ages of the patients with positive and negative EPO expression were 56.2 years and 66.6 years. Immunohistochemical EPO expression affected overall survival (OS) and disease-specific survival (DSS) rates. The DSS rates of the patients whose tissue was positive and negative for EPO expression were 85.3% and 76.1%, respectively ( p = 0.044). In a multivariate analysis, the absence of EPO expression proved to be a bad prognostic factor and negatively affected the OS ( p < 0.001) and DSS ( p < 0.001) rates. Conclusion: The absence of tumour EPO expression is an independent predictive factor with a negative effect on survival rates. The use of EPO as possible marker in the management of ccRCC patients requires further studies and a better understanding of the role of EPO in tumour biology.
Surgical Complications of Presurgical Systemic Therapy for Renal Cell Carcinoma: A Systematic Review
Authors: McCormick Barrett , Meissner Matthew A. , Karam Jose A. , Wood Christopher G. 
Published: November 2017

Background: Locally advanced and metastatic renal cell carcinoma (RCC) is associated with poor survival outcomes. The integration of presurgical systemic therapy with targeted molecular agents prior to surgical resection of RCC tumors has been utilized to improve on these outcomes. These agents may be associated with an increased risk of perioperative complications due to their action on angiogenesis and cell proliferation. Objective: To examine the evidence for the incidence and severity of perioperative complications following presurgical targeted therapy for locally advanced or metastatic RCC. Methods: We performed a systematic review of retrospective studies, prospective clinical trials, and meta-analyses using key search terms in PubMed and Medline. Studies were screened for eligibility and data were extracted by the authors. A qualitative analysis was performed and the complications for available targeted agents was reported. Results: Retrospective analyses and small prospective trials indicate varying complication rates and types based on presurgical therapies. While some studies indicate a possible increase in wound-related complications, other studies did not show similar results. Additional unique complications reported include an increase in surgical adhesions. There was not any significant difference in overall or bleeding complications. Conclusions: Overall, these studies demonstrate an acceptable level of surgical complications that should not discourage the clinician considering presurgical therapy. The results of pending trials looking at presurgical therapies will provide further information.