bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: CHEMICAL AND ELECTROCHEMICAL REDUCTION OF PYRIDO‐AS‐TRIAZINES
Authors: ARMAND J. , CHEKIR K. , PLE N. , QUEGUINER G. , SIMONNIN M. P. 
Published: April 2016

AbstractReduktionsreaktionen an Pyrido‐as‐triazinen (I) bzw. (III) werden untersucht.
ChemInform Abstract: PHOTOCHEMICAL ADDITIONS OF ALKENES TO PHTHALIMIDES TO FORM BENZAZEPINEDIONES. ADDITIONS OF DIENES, ALKENES, VINYL ETHERS, VINYL ESTERS, AND AN ALLENE
Authors: MAZZOCCHI P. H. , MINAMIKAWA S. , WILSON P. , BOWEN M. , NARIAN N. 
Published: April 2016

AbstractN‐Methylphthalimid (I) reagiert bei der Bestrahlung in Gegenwart von Butadien (II) zu den beiden stereoisomeren Addukten (III), die zu (IV) hydriert werden und deren Struktur u.a. durch photolytische Desalkylierung zu (V) bewiesen wird.
ChemInform Abstract: (5RS,7RS)‐7‐METHOXY‐1,3‐DIOXACYCLOOCT‐5(E)‐ENE. SYNTHESIS OF A STABLE BISHETERO‐TRANS‐CYCLOOCTENE, A NEW HETEROCYCLIC SYSTEM
Authors: JENDRALLA H. 
Published: April 2016

AbstractDie Desaminierung des Nitrosoharnstoffs (IV) mit NaHCO3 ergibt neben dem Ester (V) die Titelverbindung (VI), die sich in Gegenwart von I2 in das Dioxaocten (VII) umlagert und von der das Addukt (VIII) hergestellt wird.
ChemInform Abstract: METAL COMPLEXES OF FLUOROPHOSPHINES. 10. MONONUCLEAR AND BINUCLEAR CHROMIUM, MOLYBDENUM, AND TUNGSTEN CARBONYL DERIVATIVES OF (ALKYLAMINO)BIS(DIFLUOROPHOSPHINES)
Authors: KING R. B. , LEE T. W. 
Published: April 2016

AbstractDie Reaktionen der entsprechenden Norbomadienmetalltetracarbonyle mit den Titelliganden ergeben in Abhängigkeit von den Reaktionsbedingungen die Chelate (I) oder die Komplexe (II) bzw. (III) mit einzähnig gebundenen Liganden.
ChemInform Abstract: (FE3S(S2C10H12)3)2‐: THE FIRST SYNTHETIC TRINUCLEAR IRON‐SULFUR CLUSTER COMPOUND
Authors: HENKEL G. , TREMEL W. , KREBS B. 
Published: April 2016

AbstractDie Titelverbindung (I) wird durch Reaktion von 1,2‐Bis‐[mercaptomethyl]‐ 4,5‐dimethylbenzol und Na‐Methanolat mit FeCl3 und p‐Thiokresol in wasserfreiem Methanol bei anschließender F ällung mit Et4NCl erhalten (keine Ausb.‐Angabe).
ChemInform Abstract: STABILIZATION OF THE TERVALENT NICKEL COMPLEX WITH MESO‐5,7,7,12,14,14‐HEXAMETHYL‐1,4,8,11‐TETRAAZACYCLOTETRADECANE BY AXIAL COORDINATION OF ANIONS IN AQUEOUS SOLUTION
Authors: ZEIGERSON E. , BAR I. , BERNSTEIN J. , KIRSCHENBAUM L. J. , MEYERSTEIN D. 
Published: April 2016

AbstractDie elektrochemische Oxidation des Komplexes (I) in wäßriger Lösung in Gegenwart der aufgezeigten Anionen führt zu den Ni(III)‐Derivaten (II).
ChemInform Abstract: TRANS ISOMERS OF RUTHENIUM(II) COMPLEXES CONTAINING TWO BIPYRIDINE LIGANDS
Authors: WALSH J. L. , DURHAM B. 
Published: April 2016

AbstractZur Darstellung der trans‐Komplexe (I) werden drei verschiedene Reaktionen aufgezeigt Den allgemeingültigen und wirkungsvollsten Weg stellt die thermische Substitutionsreaktion der trans‐Diaquo‐Derivate dar.
ChemInform Abstract: ASYMMETRIC HYDROSILIYLATION OF KETONES, CATALYZED BY RHODIUM COMPLEXES CONTAINING CHIRAL CHELATE LIGANDS. CRYSTAL AND MOLECULAR STRUCTURE OF (BICYCLO(2.2.1)HEPTA‐2,5‐DIENE)((S)‐N,N‐DIMETHYL‐1‐(O‐(DIPHENYLARSINO)PHENYL)ETHYLAMINE)RHODIUM(I) PERCHLORATE
Authors: PAYNE N. C. , STEPHAN D. W. 
Published: April 2016

AbstractDie beiden chiralen zweizähnigen Liganden (II) werden wie aufgezeigt in guten Ausb. ,ausgehend von (R)‐ und (S)‐(I),dargestellt und 1H‐ und 31P‐NMR‐spektroskopisch charakterisiert.
ChemInform Abstract: POLYAMIDE‐CATALYZED DIMERIZATION OF 2,5‐DIHYDROXYBENZOQUINONES TO 4‐YLIDENETETRONIC ACIDS, A MODEL FOR BIOSYNTHESIS OF THE 4,4‐BOVILACTONE
Authors: JAEGERS E. + , STEGLICH W. 
Published: April 2016

AbstractDas Dihydroxybenzochinon (Ia) geht beim Behandeln mit acetyliertem Polyamid‐6 in siedendem Essigester in das Dilacton (IIa) über.
ChemInform Abstract: CHEMISTRY OF THE COCCOIDEA. VIII. SYNTHESIS OF THE ANCIENT DYE KERMESIC ACID AND OF RELATED ANTHRAQUINONES
Authors: CAMERON D. W. , DEUTSCHER D. J. , FEUTRILL G. I. , GRIFFITHS P. G. 
Published: April 2016

AbstractDiels‐Alder‐Reaktion des Dichlorbenzochinons (I) mit Z/E‐Gemischen der Diene (IIa) bzw. (IIb) liefert die Naphthochinone (IIIa) bzw. (IIIb) + (IIIc); die Ausb. an (IIIb) läßt sich durch Methylierung von (IIIc) optimieren.
ChemInform Abstract: DITERPENOID SWEETENERS. SYNTHESIS AND SENSORY EVALUATION OF STEVIOSIDE ANALOGS NONDEGRADABLE TO STEVIOL
Authors: DUBOIS G. E. , DIETRICH P. S. , LEE J. F. , MCGARRAUGH G. V. , STEPHENSON R. A. 
Published: April 2016

AbstractDurch Alkylierung von Steviolbiosid (Ia) mit 1,3‐Propansulton in Gegenwart von Kaliumcarbonat bei 25°C und anschließendem Ionenaustausch erhält man den Carbonsäureester (Ib).
ChemInform Abstract: SECONDARY METABOLITES FROM A RED ALGA (LAURENCIA INTRICATA): SESQUITERPENE ALCOHOLS
Authors: HORSLEY S. B. , CARDELLINA J. H. II , MEINWALD J. 
Published: April 2016

AbstractDie Isolierung der Sesquiterpen‐alkohole (I)‐(IV) aus der im Titel genannten Algenart wird beschrieben.
ChemInform Abstract: STRUCTURE‐ACTIVITY RELATIONSHIPS OF OXYGENATED MORPHINANS. II. SYNTHESIS AND BIOLOGICAL PROPERTIES OF 4‐METHOXYMORPHINAN‐6‐ONES WITH NARCOTIC ANTAGONIST SIDE‐CHAINS ON NITROGEN
Authors: SCHMIDHAMMER H. , JACOBSON A. E. , ATWELL L. , BROSSI A. 
Published: April 2016

AbstractDas in mehreren Stufen aus Morphin zugängliche Keton (I) ergibt über den Enolether (II) den Phenolether (III), der zur Verbindung (IVa) N‐methyliert wird.
ChemInform Abstract: ALTERNATIVE SYNTHESES OF (.+‐.)‐EPI‐ AND (.+‐.)‐DESETHYLIBOGAMINE USING A DIELS‐ALDER REACTION OF 1‐BENZYL‐2(1H)‐PYRIDONE
Authors: TOMISAWA H. , HONGO H. , KATO H. , SATO K. , FUJITA R. 
Published: April 2016

AbstractDurch Diels‐Alder Reaktion des Benzylpyridons (I) mit dem Acrylsäureester (II) erhält man ein Gemisch der Cycloaddukte (III) und (IV), von denen (IIIa) und (IVa) in die Iodlactone (V) und (VI) übergeführt werden.
ChemInform Abstract: CLEAVAGE OF DOUBLE HELICAL DNA BY METHIDIUM‐PROPYL‐EDTA‐IRON(II)
Authors: HERTZBERG R. P. , DERVAN P. B. 
Published: April 2016

AbstractDer Acyl‐ imidazolester der Säure (Ia) bildet mit 1,3‐Diamino‐propan in DMSO das Amin (Ib).
ChemInform Abstract: REARRANGEMENTS OF ALLYLIC ACETATES CATALYZED BY PALLADIUM(II): AN ENANTIOSPECIFIC SYNTHESIS OF A KEY INTERMEDIATE FOR THE PREPARATION OF 12‐HYDROXYPROSTAGLANDINS
Authors: GRIECO P. A. , TUTHILL P. A. , SHAM H. L. 
Published: April 2016

AbstractDas Acetat (Ib) des bekannten Carbinols (Ia) läßt sich mit Pd‐Katalysatoren stereospezifisch in das Acetat (II) überführen.
ChemInform Abstract: Isomorphous Substitution of Rare‐Earth Elements in Lacunary Apatite Pb8Na2(PO4)6.
Authors: Get'man Evgeni I. , Loboda Stanislav N. , Ignatov Alexey V. , Prisedsky Vadim V. , Abdul Jabar Mohammed A. B. , Ardanova Lyudmyla I. 
Published: April 2016

AbstractPb8‐xLnxNa2(PO4)6 (x = 0—2.0; Ln: Y, La, Pr—Ho, Tm—Yb) with void structural channels are prepared by solid state reaction of PbO, Na2CO3, (NH4)2HPO4, and Ln oxides (Al2O3 crucible, 800 °C, 2—10 d).
A Sensor‐Controlled Flow Apparatus for Fast Online Titrations
Authors: Fais Markus , Schwarz Christina , Leinweber Felix C. 
Published: April 2016

AbstractA process‐suitable titration apparatus was developed for fast online titrations. It consists of computer‐controlled gradient pumps, a sample dilution setup, mixing devices and a microfabricated flow cell with potentiometric sensor. The flow control of the pumps is done via the electrode response signal and a control program applying the feedback algorithm. The apparatus allows the conduction of titration experiments in time cycles of 30 – 50 s in a continuously flowing sample stream. It is about ten times faster than classical batch titrations while accuracy and precision remain of similar magnitude. The long‐term stability and the applicability to process control are shown in field tests. The presented increase of speed, decrease of size and explosion proof make titrations suitable as online technique in the process industry.
A Facile Method for Preparing Temperature‐Responsive Cell Culture Surfaces by Using a Thioxanthone Photoinitiator Immobilized on a Polystyrene Surface
Authors: Fukumori Kazuhiro , Akiyama Yoshikatsu , Yamato Masayuki , Okano Teruo 
Published: April 2016

AbstractWe developed a new facile method for the preparation of temperature‐responsive cell culture surfaces (TRCS) by photo‐polymerization of N‐isopropylacrylamide using a surface‐immobilized photoinitiator. In the first step, thioxanthone groups, which served as the photoinitiator, were directly formed on polystyrene culture dish surfaces (TX‐PSt). Second, poly(N‐isopropylacrylamide) (PIPAAm) was grafted onto the TX‐PSt surfaces (PIPAAm‐TX‐PSt) by using the visible light or light‐emitting diode irradiation‐induced surface‐initiated polymerization method. By optimizing the amount of grafted PIPAAm, the resulting PIPAAm‐TX‐PSt successfully exhibited characteristics of a TRCS. In addition, a striped micropatterned polyacrylamide area was successively formed on the photoirradiated PIPAAm‐TX‐PSt surface by using a chromium photomask. These results show that temperature‐responsive cell culture surfaces can be prepared through this new method.
Sustainable Process for the Preparation of High‐Performance Thin‐Film Composite Membranes using Ionic Liquids as the Reaction Medium
Authors: Mariën Hanne , Bellings Lotte , Hermans Sanne , Vankelecom Ivo F. J. 
Published: April 2016

AbstractA new form of interfacial polymerization to synthesize thin‐film composite membranes realizes a more sustainable membrane preparation and improved nanofiltration performance. By introducing an ionic liquid (IL) as the organic reaction phase, the extremely different physicochemical properties to those of commonly used organic solvents influenced the top‐layer formation in several beneficial ways. In addition to the elimination of hazardous solvents in the preparation, the m‐phenylenediamine (MPD) concentration could be reduced 20‐fold, and the use of surfactants and catalysts became redundant. Together with the more complete recycling of the organic phase in the water/IL system, these factors resulted in a 50 % decrease in the mass intensity of the top‐layer formation. Moreover, a much thinner top layer with a high ethanol permeance of 0.61 L m−2 h−1 bar−1 [99 % Rose Bengal (RB, 1017 Da) retention; 1 bar=0.1 MPa] was formed without the use of any additives. This EtOH permeance is 555 and 161 % higher than that for the conventional interfacial polymerization (without and with additives, respectively). In reverse osmosis, high NaCl retentions of 97 % could be obtained. Finally, the remarkable decrease in the membrane surface roughness indicates the potential for reduced fouling with this new type of membrane.
Thermodynamic Properties of Hydrogen Plasma to Megabars
Authors: Gryaznov V. K. , Iosilevskiy I. L. 
Published: April 2016

AbstractThe approach based on the chemical picture of plasma taking into account effects of Coulomb interaction, short range repulsion of atoms and molecules, free electron degeneracy for description of equilibrium composition and thermodynamic functions of non‐ideal plasma is proposed. The results of calculations of thermodynamic parameters using the models based upon this approach are presented. The parameters of thermal and caloric equation of state for hydrogen plasma were calculated from moderate to high densities in wide range of temperatures. (© 2016 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Adaptive genetic variation distinguishes Chilean blue mussels (Mytilus chilensis) from different marine environments
Authors: Araneda Cristián , Larraín María Angélica , Hecht Benjamin , Narum Shawn 
Published: April 2016

AbstractChilean mussel populations have been thought to be panmictic with limited genetic structure. Genotyping‐by‐sequencing approaches have enabled investigation of genomewide variation that may better distinguish populations that have evolved in different environments. We investigated neutral and adaptive genetic variation in Mytilus from six locations in southern Chile with 1240 SNPs obtained with RAD‐seq. Differentiation among locations with 891 neutral SNPs was low (FST = 0.005). Higher differentiation was obtained with a panel of 58 putative outlier SNPs (FST = 0.114) indicating the potential for local adaptation. This panel identified clusters of genetically related individuals and demonstrated that much of the differentiation (~92%) could be attributed to the three major regions and environments: extreme conditions in Patagonia, inner bay influenced by aquaculture (Reloncaví), and outer bay (Chiloé Island). Patagonia samples were most distinct, but additional analysis carried out excluding this collection also revealed adaptive divergence between inner and outer bay samples. The four locations within Reloncaví area were most similar with all panels of markers, likely due to similar environments, high gene flow by aquaculture practices, and low geographical distance. Our results and the SNP markers developed will be a powerful tool supporting management and programs of this harvested species.
Temperature and population density: interactional effects of environmental factors on phenotypic plasticity, immune defenses, and disease resistance in an insect pest
Authors: Silva Farley W. S. , Elliot Simon L. 
Published: April 2016

AbstractTemperature and crowding are key environmental factors mediating the transmission and epizooty of infectious disease in ectotherm animals. The host physiology may be altered in a temperature‐dependent manner and thus affects the pathogen development and course of diseases within an individual and host population, or the transmission rates (or infectivity) of pathogens shift linearly with the host population density. To our understanding, the knowledge of interactive and synergistic effects of temperature and population density on the host–pathogen system is limited. Here, we tested the interactional effects of these environmental factors on phenotypic plasticity, immune defenses, and disease resistance in the velvetbean caterpillar Anticarsia gemmatalis. Upon egg hatching, caterpillars were reared in thermostat‐controlled chambers in a 2 × 4 factorial design: density (1 or 8 caterpillars/pot) and temperature (20, 24, 28, or 32°C). Of the immune defenses assessed, encapsulation response was directly affected by none of the environmental factors; capsule melanization increased with temperature in both lone‐ and group‐reared caterpillars, although the lone‐reared ones presented the most evident response, and hemocyte numbers decreased with temperature regardless of the population density. Temperature, but not population density, affected considerably the time from inoculation to death of velvetbean caterpillar. Thus, velvetbean caterpillars succumbed to Anticarsia gemmatalis multiple nucleopolyhedrovirus (AgMNPV) more quickly at higher temperatures than at lower temperatures. As hypothesized, temperature likely affected caterpillars' movement rates, and thus the contact between conspecifics, which in turn affected the phenotypic expression of group‐reared caterpillars. Our results suggest that environmental factors, mainly temperature, strongly affect both the course of disease in velvetbean caterpillar population and its defenses against pathogens. As a soybean pest, velvetbean caterpillar may increase its damage on soybean fields under a scenario of global warming as caterpillars may reach the developmental resistance faster, and thus decrease their susceptibility to biological control by AgMNPV.
In vivo engineering of mobilized stem cell grafts with the immunomodulatory drug FTY720 for allogeneic transplantation
Authors: Lakshmikanth Tadepally , Heuts Frank , Muvva S. S. V. Jagadeeswara Rao , Wallin Robert P. A. , Persson Anna‐Karin , Fauriat Cyril , Applequist Steven E. , Ljunggren Hans‐Gustaf , Höglund Petter , Kärre Klas , Svensson Mattias , Juarez Julius G. 
Published: April 2016

The immunological attributes of stem cell grafts play an important role in the outcome of allogeneic stem cell transplants. Currently, ex vivo manipulation techniques such as bulk T‐cell depletion or positive selection of CD34+ cells are utilized to improve the immunological attributes of grafts and minimize the potential for graft‐versus‐host disease (GvHD). Here, we demonstrate a novel graft engineering technique, which utilizes the immunomodulatory drug FTY720 for in vivo depletion of naïve T (TN) cells from donor G‐CSF‐mobilized grafts without ex vivo manipulation. We show that treatment of donor mice with FTY720 during mobilization depletes grafts of TN cells and prevents lethal GvHD following transplantation in a major mismatch setting. Importantly, both stem cells and NK cells are retained in the FTY720‐treated grafts. FTY720 treatment does not negatively affect the engraftment potential of stem cells as demonstrated in our congenic transplants or the functionality of NK cells. In addition, potentially useful memory T cells may be retained in the graft. These findings suggest that FTY720 may be used to optimize the immunological attributes of G‐CSF‐mobilized grafts by removing potentially deleterious TN cells which can contribute to GvHD, and by retaining useful cells which can promote immunity in the recipient.
A Weinreb Amide Based Building Block for Convenient Access to β,β‐Diarylacroleins: Synthesis of 3‐Arylindanones
Authors: Tiwari Praveen Kumar , Aidhen Indrapal Singh 
Published: April 2016

AbstractTowards the synthesis of symmetrical and unsymmetrical β,β‐diarylacroleins for assembling diarylmethine fragments present in biologically important molecules, we have developed a new Weinreb amide (WA) based building block, derived from propiolic acid. The WA functionality present in this compound allowed the sequential addition of various arylmagnesium bromide reagents in a controlled manner. The developed methodology for the access to β,β‐diarylacroleins has been utilised for the synthesis of biologically important 3‐arylindanone molecules.
On the Multicycle Activity of Natural Limestone/Dolomite for Thermochemical Energy Storage of Concentrated Solar Power
Authors: Sarrion Beatriz , Valverde Jose Manuel , Perejon Antonio , Perez‐Maqueda Luis , Sanchez‐Jimenez Pedro E. 
Published: April 2016

AbstractCheap, efficient, and non‐toxic energy storage technologies are urgently needed to handle the rapidly increasing penetration of intermittent renewable energies into the grid. This work explores the use of limestone and dolomite for energy storage in concentrated solar power (CSP) plants by means of the calcium looping (CaL) process based on the multicycle carbonation/calcination of CaO. An efficient integration of the CaL process into CSP plants involves high temperature carbonation and calcination at moderate temperatures in a close CO2 cycle for power generation. These conditions differ from those of the CaL process for CO2 capture, which lead to CaO deactivation as extensively reported in recent years. In contrast, we show that limestone‐ and dolomite‐derived CaO give rise to a high residual conversion at CaL–CSP conditions and in short residence times, which would facilitate the development of a competitive and clean CSP technology with permanent energy storage.
Superposition network coded cooperation for wireless networks
Authors: Fazeli Ali , Omidi Mohammad Javad , Saeedi‐Sourck Hamid , Ardakani Masoud 
Published: April 2016

AbstractCooperative diversity is an innovative approach to improve the reliability of communication. Although this technique is considered in the next‐generation mobile communication standards, it has its own challenges in practice. For example, in simultaneous transmission‐based cooperative protocols, perfect synchronisation of nodes is very hard to realise. The traditional time division multiple access method can simplify the synchronisation problems but leads to long transmission delays. In this paper, a low‐delay cooperative strategy is proposed for a network with multiple sources and a single destination, which requires only a simple type of synchronisation. In this technique, we use a combination of superposition coding and network coding; hence the name superposition network coded cooperation. For this strategy, good bounds are obtained for the probability of correct detection for general M‐PSK and M‐QAM modulation and are compared with simulation results. The results demonstrate improvement in error performance compared with other transmission schemes requiring the same transmission time as superposition network coded cooperation. Copyright © 2016 John Wiley & Sons, Ltd.
Degradation of La0.6Sr0.4Co0.2Fe0.8O3–δ–Ce0.8Sm0.2O1.9 Cathodes on Coated and Uncoated Porous Metal Supports
Authors: Harris J. , Yan Y. , Bateni R. , Kesler O. 
Published: April 2016

AbstractThe degradation of composite LSCF‐SDC cathodes on porous 430 stainless steel supports was investigated. Two degradation mechanisms were observed: a multi‐layer oxide scale, believed to consist of Cr2O3 and SrCrO4, formed at the support‐cathode interface, and small amounts of chromium were detected within the cathodes. To reduce degradation, La2O3 and Y2O3 reactive element oxide coatings were deposited on the internal pore surfaces of the metal supports. The reactive element oxide coatings reduced the amount of volatile chromium that deposited in the cathodes. As a result, the degradation rates of the cathodes on coated supports were significantly lower than the degradation rates of cathodes made on uncoated metal supports. In cathode symmetrical cells, polarization resistance degradation rates as low as 2.56 × 10−6 Ω cm2 h−1 were observed over 100 hours on coated metal supports, compared to an average of 1.23 × 10−4 Ω cm2 h−1 on uncoated supports.
A biological study establishing the endotoxin limit of biomaterials for bone regeneration in cranial and femoral implantation of rats
Authors: Haishima Yuji , Hasegawa Chie , Todoki Kazuo , Sasaki Kazuo , Niimi Shingo , Ozono Satoru 
Published: April 2016

AbstractThe purpose of this study was to accurately quantify the risk of endotoxin contamination in biomaterials for bone regeneration in order to establish the acceptable endotoxin limit. Collagen sheets containing varying amounts of purified endotoxin from Escherichia coli and dried, heat‐killed E. coli or Staphylococcus aureus cells were implanted into cranial or femoral defects in rats. These defects were artificially prepared to a size of 5 × 5 mm or a diameter of 1 mm, respectively. The degree of osteoanagenesis was assessed by soft X‐ray radiography and histopathology at 1 and 4 weeks after implantation. The collagen sheet containing the dried E. coli cells showed a dose‐dependent delay in cranial and/or femoral osteoanagenesis at endotoxin activities of more than 33.6 EU/mg, at which no inflammatory response was observed. In contrast, no such observation occurred with the collagen sheet containing S. aureus cells. These results suggest that endotoxins may affect the process of osteoanagenesis. Additionally, the no‐observed‐adverse‐effect level was 9.6 EU/mg, corresponding to 255 EU/kg body weight in rats. Interestingly, no delay in osteoanagenesis was induced by the implantation of collagen sheets containing purified endotoxin at any dose tested. This suggested that pure endotoxin implanted into tissues having poor circulation of bodily fluids without bleeding may not be recognized as a foreign substance and may not induce a significant biological response. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 1514–1524, 2017.