bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of hypertension in progression of chronic kidney disease in children
Authors: Vidi Smitha R. 
Published: January 2018

Purpose of review
Hypertension is an independent risk factor for progression of chronic kidney disease (CKD) in children. Children with early CKD develop hypertension secondary to renal disease. This review aims to highlight recent advances that help us better understand the current role of hypertension in progression of CKD in children.

Recent findings
There is increasing evidence that children with CKD who have hypertension develop early atherosclerosis and cardiac adaptive changes. Emerging data from pediatric research in CKD show that elevated blood pressure is associated with the presence of abnormal subclinical markers of cardiovascular disease including increased carotid intima-media thickness, pulse wave velocity and left ventricular mass index. There is also some evidence that these early cardiovascular changes are reversible. Twenty-four hour ambulatory blood pressure monitoring (ABPM) is recommended in children with CKD by the American Academy of Pediatrics to diagnose hypertension.

Summary
Hypertension is associated with subclinical cardiovascular disease in children with CKD. Early diagnosis of hypertension by ABPM and identification of subclinical cardiovascular changes provide a window for intervention, which may reverse early cardiovascular disease, thereby delaying dialysis and improving cardiovascular morbidity and mortality.
Idiopathic Sclerosing Orbital Inflammation in a Relapsing Polychondritis Patient With Impaired Vision
Authors: Wang Chrong-Reen , Hsu Sheng-Min , Chen Ying-Chen , Ho Chung-Liang , Fang Sheen-Yie 
Published: January 2018

Abstract
A 55-year-old woman with relapsing polychondritis had progressively enlarged right retro-orbital tumor invading the optic nerve, followed by left retrobulbar infiltrating lesions despite prescription of high-dose corticosteroids and pulse methylprednisolone. Repeated histopathologic analyses showed dense collagen fibers with scanty inflammatory cells, consistent with the diagnosis of idiopathic sclerosing orbital inflammation. This disorder has been recognized as a distinct entity with unique clinical features and coexisting rheumatologic disorders, requiring more focused diagnostic strategies and therapeutic regimens. In summary, we demonstrate a rare ocular manifestation in relapsing polychondritis and emphasize the importance of serial radiological and pathological evaluations in such patients presenting with exophthalmos.
Evaluation of Vitamin B12 Deficiency and Associated Factors in Patients With Systemic Sclerosis
Authors: Tas Kilic Diler , Akdogan Ali , Kilic Levent , Sari Alper , Erden Abdulsamet , Armagan Berkan , Kilickaya Muhammed , Kalyoncu Umut , Turhan Turan , Kiraz Sedat , Karaahmetoglu Selma 
Published: January 2018

Background/Objective
In patients with systemic sclerosis (SSc) gastrointestinal (GI) involvement, nutritional status and medications may lead to cobalamin (Vit B12) deficiency. We aimed to determine the frequency and the potential causes of Vit B12 deficiency in SSc patients.

Methods
We conducted a cross-sectional analysis of 62 SSc patients in a single center in 1 year period. Medical history and physical examination of patients were reevaluated. Data about organ involvements were obtained from hospital file records. The nutritional status of the patients was assessed with Malnutrition Universal Screening Tool (MUST). Vit B12, homocysteine (except in three patients) and Helicobacter Pylori Immunoglobulin G (H. Pylori IgG) levels were measured in all patients. Vit B12 deficiency was considered as serum Vit B12 level <200 pg/mL or being on Vit B12 replacement therapy. Serum Vit B12 levels of the patients were also grouped as low (<200 pg/mL), borderline (200–300 pg/mL) and normal (>300 pg/mL). Plasma homocysteine levels of the patients were classified as elevated (>9 μmol/L) and hyperhomocysteinemia (>15 μmol/L). Mann–Whitney U and Kruskal–Wallis tests were used to compare parameters among the groups. Correlation was tested by Spearman’s correlation coefficient.

Results
Forty-four (71.0%) patients were defined as Vit B12 deficient; 22 had Vit B12 level <200 pg/mL (four were on Vit B12 replacement therapy) and the remaining 22 had Vit B12 >200 pg/mL and were already on Vit B12 replacement therapy. The percentage of the patients with hyperhomocysteinemia was significantly higher in the group with Vit B12 <200 pg/mL as compared to other groups (P = 0.004) but only 33.3% (7/21) of the patients with Vit B12 <200 pg/mL had hyperhomocysteinemia. There were no statistically significant differences between patients with and without Vit B12 deficiency regarding age, mean disease duration, MUST scores, mean hemoglobin levels, H. Pylori IgG positivity and organ involvements (P > 0.05 for all).

Conclusions
Vit B12 deficiency is frequent in SSc and has multiple causes. All patients should be monitored for Vit B12 deficiency. The homocysteine levels seem unlikely to be helpful for confirmation of Vit B12 deficiency.
Cross-modality Accuracy of Dual-step, Prospectively Electrocardiography-triggered Dual-source Computed Tomorgaphy Compared With Same-day Echocardiography and Cardiac Magnetic Resonance Imaging in the Follow-up of Heart-transplant Patients
Authors: Marano Riccardo , Merlino Biagio , Natale Luigi , Savino Giancarlo , Vingiani Vincenzo , Rovere Giuseppe , Larici Anna Rita , Iezzi Roberto , Magarelli Nicola , Lombardo Antonella , Pasquale Massimo , Manfredi Riccardo 
Published: January 2018

Purpose:
An accurate evaluation of left ventricular volumes, mass, and ejection fraction (EF) and an early exclusion or detection of significant coronary artery disease or cardiac allograft vasculopathy are mandatory for clinical management and prognosis assessment of heart-transplanted patients (HTP). The purpose of this article was to evaluate the role of dual-step prospective electrocardiography-triggered Dual-Source CT (pECGdual-step-DSCT) in HTP for the assessment of left-ventricular function, in comparison with echocardiography (echo) and cardiac magnetic resonance (CMR) performed on the same day, and of the coronary arteries as well.

Materials and Methods:
Left-ventricular EF, end-diastolic volume, end-systolic volume, stroke volume, cardiac output (CO), and mass were assessed in 11 HTP by pECGdual-step-DSCT in comparison with CMR and echo performed on the same day. During all the examinations, the heart rate was recorded. CT coronary artery assessment was also performed.

Results:
Heart rate was lower during DSCT (75.6±7.8 bpm; P<0.001). EF resulted slightly lower for DSCT (55.7%±5.0%; P≥0.05) in comparison with CMR (57.8%±5.3%; P≥0.05) and echo (59.2%±5.6%; P≥0.05). DSCT showed statistically significant higher end-diastolic volume (153.7±24.2 mL), end-systolic volume (67.8±11.5 mL), and stroke volume (85.9±17.6 mL) (P<0.01 up to 0.001) than CMR, but with a high correlation (P<0.001). Cardiac output was almost similar for DSCT versus CMR, with a very high correlation coefficient (r=0.914; P<0.001). DSCT showed higher mass values than CMR (P<0.001), but with a high correlation (r=0.866; P<0.001). DSCT versus echo results were less correlated. No significant coronary artery disease was detected.

Conclusion:
pECGdual-step-DSCT allows reliable assessment of left-ventricular function in HTP, with good agreement and correlation with CMR, within a global diagnostic approach including coronary artery evaluation in one single-volume acquisition.
Ghosts of infections past: using archival samples to understand a century of monkeypox virus prevalence among host communities across space and time
Authors: Tiee Madeline S. , Harrigan Ryan J. , Thomassen Henri A. , Smith Thomas B. 
Published: January 2018

Infectious diseases that originate from multiple wildlife hosts can be complex and problematic to manage. A full understanding is further limited by large temporal and spatial gaps in sampling. However, these limitations can be overcome, in part, by using historical samples, such as those derived from museum collections. Here, we screened over 1000 museum specimens collected over the past 120 years to examine the historical distribution and prevalence of monkeypox virus (MPXV) in five species of African rope squirrel (
Funisciurus
sp.) collected across Central Africa. We found evidence of MPXV infections in host species as early as 1899, half a century earlier than the first recognized case of MPXV in 1958, supporting the suggestion that historic pox-like outbreaks in humans and non-human primates may have been caused by MPXV rather than smallpox as originally thought. MPX viral DNA was found in 93 of 1038 (9.0%) specimens from five
Funisciurus
species (
F. anerythrus
,
F. carruthersi
,
F. congicus
,
F. lemniscatus
and
F. pyrropus
), of which
F. carruthersi
and
pyrropus
had not previously been identified as potential MPXV hosts. We additionally documented relative prevalence rates of infection in museum specimens of
Funisciurus
and examined the spatial and temporal distribution of MPXV in these potential host species across nearly a hundred years (1899–1993).
Offline coil position denoising enhances detection of TMS effects
Authors: Claudino Leonardo , Hussain Sara J , Buch Ethan R , Cohen Leonardo G 
Published: January 2018

AbstractOBJECTIVETranscranial magnetic stimulation (TMS) is extensively used in basic and clinical neuroscience. Previous work has shown substantial residual variability in TMS effects even despite use of on-line visual feedback monitoring of coil position. Here, we aimed to evaluate if off-line denoising of variability induced by neuronavigated coil position and orientation deviations can enhance detection of TMS effects.METHODSRetrospective modeling was used to denoise the impact of common neuronavigated coil position and rotation deviations during TMS experimental sessions on motor evoked potentials (MEP) to single pulse TMS.RESULTSNeuronavigated coil deviations explained approximately 44% of total MEP amplitude variability. Offline denoising led to a 136.71% improvement in the signal to noise ratio (SNR) of corticospinal excitability measurements. CONCLUSIONS: Offline modeling enhanced detection of TMS effects by removing variability introduced by neuronavigated coil deviations.SIGNIFICANCEThis approach could allow more accurate determination of TMS effects in cognitive and interventional neuroscience.HIGHLIGHTSCoil deviations impact TMS effects despite use of on-line neuronavigation feedback.Offline denoising of coil deviation impacts on TMS effects significantly reduced variability at trial level.Offline denoising also significantly improved overall SNR of TMS effects.
SPOKEdb: open-source information management system for oral history
Authors: Weig Eric C. , Slone MLE 
Published: January 2018

Purpose
This paper aims to examine how an open-source information management system was developed to manage a collection of more than 10,000 oral history interviews at the University of Kentucky Libraries’ Louie B. Nunn Center for Oral History.

Design/methodology/approach
Digital library architects at the University of Kentucky Libraries built an open-source information management system for oral history using the open-source tools Omeka and Blacklight. Additional open-source code was developed to facilitate interaction between these tools.

Findings
Information management systems that address needs of libraries and archives can be built by combining existing open-source tools in complementary ways.

Originality/value
This work at the University of Kentucky Libraries serves as a proof of concept for other institutions to examine as a potential model to follow or adapt for their own local needs. The SPOKEdb framework can be replicated elsewhere, as the major and minor components are open-source. SPOKEdb at its conceptual level is a unique information management system based on its tailored approach to serving the needs of oral history management at various user levels including both administrative and public.
Knowledge hiding and team creativity: the contingent role of task interdependence
Authors: Fong Patrick S.W. , Men Chenghao , Luo Jinlian , Jia Ruiqian 
Published: January 2018

PurposeCreativity and innovation are crucial in improving the organizational performance and sustaining competitive advantage. The purpose of this paper is to investigate the relationship between knowledge hiding and team creativity.Design/methodology/approachThe authors tested the hypotheses with a sample of 87 knowledge worker teams involving 393 employees and employers in China.FindingsKnowledge hiding is negatively related to team creativity, fully mediated by absorptive capacity. In addition, the negative relationship between knowledge hiding and absorptive capacity would be weakened by task interdependence.Practical implicationsTeam managers should take measures to avoid the development of knowledge hiding, which is indirectly related to team creativity via absorptive capacity within a team, and motivate team members to share more knowledge by training to improve their feelings of accountability, responsibility, and duty. In addition, managers can decrease knowledge hiding by strengthening within-team task interdependence.Originality/valueThis study is one of the first to investigate the relationship between knowledge hiding and team creativity and the moderating role of task interdependence in the relationship between knowledge hiding and absorptive capacity.
An adaptive free‐surface expression for three‐dimensional finite‐difference frequency‐domain modelling of elastic wave
Authors: Cao Jian , Chen Jing‐Bo , Dai Meng‐Xue 
Published: January 2018

ABSTRACTFinite‐difference frequency‐domain modelling of seismic wave propagation is attractive for its efficient solution of multisource problems, and this is crucial for full‐waveform inversion and seismic imaging, especially in the three‐dimensional seismic problem. However, implementing the free surface in the finite‐difference method is nontrivial. Based on an average medium method and the limit theorem, we present an adaptive free‐surface expression to describe the behaviour of wavefields at the free surface, and no extra work for the free‐surface boundary condition is needed. Essentially, the proposed free‐surface expression is a modification of density and constitutive relation at the free surface. In comparison with a direct difference approximate method of the free‐surface boundary condition, this adaptive free‐surface expression can produce more accurate and stable results for a broad range of Poisson's ratio. In addition, this expression has a good performance in handling the lateral variation of Poisson's ratio adaptively and without instability.
Accelerating the T‐matrix approach to seismic full‐waveform inversion by domain decomposition
Authors: Jakobsen Morten , Wu Ru‐Shan 
Published: January 2018

ABSTRACTA seismic variant of the distorted Born iterative inversion method, which is commonly used in electromagnetic and acoustic (medical) imaging, has been recently developed on the basis of the T‐matrix approach of multiple scattering theory. The distorted Born iterative method is consistent with the Gauss–Newton method, but its implementation is different, and there are potentially significant computational advantages of using the T‐matrix approach in this context. It has been shown that the computational cost associated with the updating of the background medium Green functions after each iteration can be reduced via the use of various linearisation or quasi‐linearisation techniques. However, these techniques for reducing the computational cost may not work well in the presence of strong contrasts. To deal with this, we have now developed a domain decomposition method, which allows one to decompose the seismic velocity model into an arbitrary number of heterogeneous domains that can be treated separately and in parallel. The new domain decomposition method is based on the concept of a scattering‐path matrix, which is well known in solid‐state physics. If the seismic model consists of different domains that are well separated (e.g., different reservoirs within a sedimentary basin), then the scattering‐path matrix formulation can be used to derive approximations that are sufficiently accurate but far more speedy and much less memory demanding because they ignore the interaction between different domains. However, we show here that one can also use the scattering‐path matrix formulation to calculate the overall T‐matrix for a large model exactly without any approximations at a computational cost that is significantly smaller than the cost associated with an exact formal matrix inversion solution. This is because we have derived exact analytical results for the special case of two interacting domains and combined them with Strassen's formulas for fast recursive matrix inversion. To illustrate the fact that we have accelerated the T‐matrix approach to full‐waveform inversion by domain decomposition, we perform a series of numerical experiments based on synthetic data associated with a complex salt model and a simpler two‐dimensional model that can be naturally decomposed into separate upper and lower domains. If the domain decomposition method is combined with an additional layer of multi‐scale regularisation (based on spatial smoothing of the sensitivity matrix and the data residual vector along the receiver line) beyond standard sequential frequency inversion, then one apparently can also obtain stable inversion results in the absence of ultra‐low frequencies and reduced computation times.
Foundation for an evidence‐informed algorithm for treating pelvic floor mesh complications: a review
Authors: Cundiff GW , Quinlan DJ , van Rensburg JA , Slack M 
Published: January 2018

AbstractTo address evidence gaps on the management of complications related to mesh in pelvic floor surgery, we created an evidence‐based algorithm that includes defining evidence gaps. We utilized the Delphi method within a panel of surgeons treating mesh complications to define a treatment strategy. The first round provided a list of clinically based postulates that informed a review expanding postulates to recommendations and included grading of the quality of evidence. A second round informed the final algorithm. While the quality of the available evidence is low, it provides a framework for planning diagnosis and management of mesh‐related complications.Tweetable abstractRemoval of mesh must balance resolution of complications with the risk of removal and recurrence of pelvic floor symptoms.
Limited association between markers of stress during pregnancy and fetal growth in ‘Born into Life’, a new prospective birth cohort
Authors: Smew Awad I. , Hedman Anna M. , Chiesa Flaminia , Ullemar Vilhelmina , Andolf Ellika , Pershagen Göran , Almqvist Catarina 
Published: January 2018

AbstractAimsWe aimed to investigate the associations between perceived maternal stress or salivary cortisol levels during pregnancy and birthweight.MethodsIn 2010–2012, we recruited 92 women living in Stockholm, Sweden, and followed them from before conception and through pregnancy and childbirth. Their Perceived Stress Scale (PSS) scores and salivary cortisol levels were collected at 26–28 gestational weeks. Birthweight was collected from medical records. Linear regression analyses and Pearson correlations were performed between the PSS scores or cortisol levels and birthweight, respectively, adjusted for gestational age.ResultsNo significant associations were found between PSS scores or cortisol levels and birthweight. There was a trend towards higher salivary cortisol levels among infants with lower birthweights, and this effect was attenuated after adjusting for gestational age. Morning cortisol levels (r = −0.31, p = 0.01), the decline in cortisol levels (r = −0.26, p = 0.03) and evening cortisol levels (r = −0.21, p = 0.09) were negatively correlated with PSS scores.ConclusionMaternal stress during pregnancy was not associated with birthweight. The inverse correlation between PSS scores and cortisol levels may indicate other mechanisms for maternal stress on child outcomes than the previous explanation of hypothalamic‐pituitary‐adrenal axis activity.
Retrospective observational study indicates that the paediatric assessment triangle may suggest the severity of Kawasaki disease
Authors: Kawai Reiko , Nomura Osamu , Tomobe Yutaro , Morikawa Yoshihiko , Miyata Koichi , Sakakibara Hiroshi , Miura Masaru 
Published: January 2018

AbstractAimWe examined whether the paediatric assessment triangle (PAT) could predict the severity of Kawasaki disease.MethodsWe enroled patients diagnosed with Kawasaki disease between July 2012 and June 2016 at the emergency department of Tokyo Metropolitan Children's Medical Center in Tokyo, Japan. Triage nurses assigned participants to unstable or stable PAT groups. We compared the incidence of coronary artery aneurysms (CAA), the Kobayashi score, which measures resistance to intravenous immunoglobulin treatment, and the incidence of initial treatment resistance.ResultsOf the 420 participants, who were aged 0‐145 months with a mean age of 31.2 ± 23.9 months, 66 (16%) were assigned to the unstable PAT group. The incidence of CAA was similar between the two groups. The percentage of unstable PAT group participants with a Kobayashi score of at least five points (39 versus 18%, p < 0.001) and initial treatment resistance (25 versus 15%, p = 0.047) were significantly higher than in the stable PAT group. Unstable PAT was an independent risk factor for initial treatment resistance (odds ratio 2.02, 95% confidence interval 1.05‐3.90, p = 0.035).ConclusionAn unstable PAT was able to predict the severity of Kawasaki disease when measured by a higher rate of initial treatment resistance.
The effect of a practical nutrition education programme on feeding skills of caregivers of children with cerebral palsy at Muhimbili National Hospital, in Tanzania
Authors: Mlinda S. J. , Leyna G. H. , Massawe A. 
Published: January 2018

AbstractBackgroundFeeding children with cerebral palsy (CP) is challenging and can lead to poor health outcomes. Using a facility‐based intervention, we assessed the effect of a practical nutrition programme on feeding skills in caregivers of children with CP attending a pediatric clinic in urban Tanzania.MethodsA randomized‐controlled intervention study, involving 2‐block stratified sample of under‐5 CP children attending a specialized pediatric clinic at the Muhimbili National Hospital was done. One hundred ten moderate‐to‐severe, new and follow‐up cases of children with CP were randomly allocated to the intervention (N = 63) and control groups (N = 47). A short nutrition education on feeding and positioning skills was provided to caregivers and occupational therapy sessions to CP children. Bivariate and multivariable logistic regression analyses of collected data were done. Statistical significance was assessed at p < .05.FindingsThe intervention significantly improved feeding skills of caregiver in the select indicators assessed. More caregivers appropriately positioned the children (AOR = 5.29; 95% CI: 2.00–13.96), fed children slowly (AOR: 5.17, 95% CI: 1.99–13.44), and involved the child during the feeding process (AOR = 3.46; 95% CI: 1.42–8.44). During feeding, caregiver's reported being less stressed (AOR = 2.53, 95% CI: 1.04–6.13) and the child's mood was more likely to be reported as improved (AOR = 3.15, 95% CI: 1.33–7.474). Although changes were observed in oral motor feeding skills (AOR = 1.67; 95% CI: 0.72–3.91) and functional feeding skills (AOR = 2.28; 95% CI: 0.86–6.06), they did not reach statistical significance in the multivariable models.ConclusionStrengthening nutrition education and services for caregivers of children with CP has great value in the care of children with special needs and may improve the health outcomes of children as well as reduce stress among parents/caregivers.