bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Marginal Zone B Cell Compartment and T Cell–independent Antibody Responses Are Supported by B Cell Intrinsic Expression of IRF1
Authors: Peel Jessica N , Owiredu Eddie-Williams , Rosenberg Alexander F , Silva-Sanchez Aaron , Randall Troy D , Kearney John F , Lund Frances E 
Published: October 2024

Abstract
The prototypic IFN-inducible transcription factor, IRF1, not only controls inflammatory gene expression but also regulates T cell and macrophage fate specification and function. Using bone marrow chimeras (80% B6.129S2-Ighmtm1Cgn/J [µMT] + 20% B6.129S2-Irf1tm1Mak/J [Irf1−/−]), we show that IRF1 expression in B cells is required for marginal zone B (MZB) cell development and T cell–independent Ab responses. Although IFNs can induce IRF1 expression in MZB precursors, deletion of the IFN-γR (C57BL/6J [B6], B6.129S7-Ifngr1tm1Agt/J) or IFN-αR (B6[Cg]-Ifnar1tm1Agt/J) did not affect MZB cell development. Instead, BCR and TLR signals promote IRF1 expression and nuclear translocation in MZB cell precursors. In turn, IRF1 is required for Notch2-dependent gene expression in BCR- and TLR-stimulated transitional B cells and development of the MZB cell compartment. Thus, IRF1 regulates MZB-driven T cell–independent Ab responses by regulating Notch programming in MZB precursors and facilitating commitment of these cells to the MZB lineage.
Drug-eluting beads chemoembolization combined with programmed cell death 1 inhibitor and lenvatinib for large hepatocellular carcinoma
Authors: Yang Hui , Qiu Guang-Ping , Liu Jie , Yang Tie-Quan 
Published: October 2024

BACKGROUND
The combination of transarterial chemoembolization (TACE), lenvatinib, and programmed cell death 1 (PD-1) inhibitor has been widely used in the treatment of advanced hepatocellular carcinoma (HCC) and has achieved promising results. However, there are few studies comparing whether drug-eluting beads TACE (D-TACE) can bring more survival benefits to patients with large HCC compared to conventional TACE (C-TACE) in this triplet therapy.
AIM
To compare the efficacy and adverse events (AEs) of triple therapy comprising D-TACE, PD-1 inhibitors, and lenvatinib (D-TACE-P-L) and C-TACE, PD-1 inhibitors, and lenvatinib (C-TACE-P-L) in patients with large HCC (maximum diameter ≥ 5 cm), and analyze the prognostic factors.
METHODS
Following a comprehensive review of our hospital’s medical records, this retrospective study included 104 patients: 50 received D-TACE-P-L, and 54 received C-TACE-P-L. We employed Kaplan-Meier estimation to assess the median progression-free survival (PFS) between the two groups, utilized Cox multivariate regression analysis to identify prognostic factors, and applied the χ 2 test to evaluate AEs.
RESULTS
The objective response rate (ORR) and median PFS were significantly higher in the D-TACE-P-L group compared to the C-TACE-P-L group (ORR: 66.0% vs 44.4%, P = 0.027; median PFS: 6.8 months vs 5.0 months, P = 0.041). Cox regression analysis identified treatment option, portal vein tumor thrombus, and hepatic vein invasion as protective factors for PFS. AEs were comparable between the two groups.
CONCLUSION
D-TACE-P-L may have significantly better PFS and ORR for large HCC, while exhibiting similar AEs to C-TACE-P-L.
Effect of endoscopic submucosal dissection on gastrointestinal function and nutritional status in patients with early gastric cancer
Authors: Xu Qi-De , Liu Hua , Zhang Hui-Wen , Gao Xiao-Mao , Li Ying-Guang , Wu Zuo-Yan 
Published: October 2024

BACKGROUND
Gastric cancer (GC) endangers the survival and prognosis of patients worldwide. Improving the prognosis of patients with early GC (EGC) is crucial to prolong their survival time.
AIM
To analyze the effects of endoscopic submucosal dissection (ESD) on gastrointestinal function and nutritional status in patients with EGC.
METHODS
Eighty patients with EGC between January 2021 and January 2024 were divided according to different surgical protocol into following two groups: 42 patients who underwent ESD in the ESD group and 38 patients treated with endoscopic mucosal resection (EMR) in the EMR group. Two groups were compared in the operative indices, lesion resection rate, postoperative recovery of gastrointestinal function, nutritional status, and incidence of surgical complications.
RESULTS
The overall resection rate of the lesion in the ESD group was higher. The operative bleeding volume and operation time were higher and gastrointestinal ventilation time was shorter in the ESD group than those in the EMR group (P < 0.05). The nutritional statuses of the two groups decreased after operation; however, the levels of albumin, prealbumin, hemoglobin, and transferrin were higher in the ESD group than in the EMR group (P < 0.05). The post-operative pepsinogen (PG) I level in the ESD group was higher than that in the EMR group, and the PG II level was lower than that in the EMR group (P < 0.05). The incidence of postoperative complications was compared between the two groups (P > 0.05).
CONCLUSION
ESD can promote the immediate recovery of patient’s postoperative gastrointestinal function, improve their nutritional level, and signifies its application in patients with EGC.
Comparison of clinical features of patients with or without severe gastrointestinal complications in aggressive gastrointestinal lymphomas
Authors: Liu Xiao-Hong , Chen Gong , Cao De-Dong , Liu Hui , Ke Xiao-Kang , Hu Yu-Gang , Tan Wei , Ke Dong , Xu Xi-Ming 
Published: October 2024

BACKGROUND
Aggressive primary gastrointestinal non-Hodgkin lymphoma (PGINHL) is an uncommon and heterogeneous group of lymphoid malignancies, that differs from indolent lymphoma and has a high incidence of severe gastrointestinal complications (GICs).
AIM
To investigate and compare the clinicopathological characteristics, treatments and outcomes in the GICs and No-GICs group with aggressive PGINHL.
METHODS
This retrospective analysis was performed on aggressive PGINHL patients between January 2013 and December 2021 at our hospital. The independent influence factors of GICs were obtained by univariate and multivariate Logistic regression analysis, the selected variables significantly related to GICs were selected as the final predictors to construct nomogram. Kaplan-Meier curves further analyzed the survival of patients in GICs and No-GICs groups. Survival analysis of GICs group was performed using Cox regression.
RESULTS
We focused on 124 aggressive PGINHL cases, which had a relatively high incidence 48.4% (60/124 cases) of GICs, the most common histological type in GICs group was diffuse large B-cell lymphoma (DLBCL) (n = 49, 81.7%). In the GICs group, small intestine was the most common anatomic site of lesion (43.3%), followed by large intestine (31.7%), and then stomach and esophagus (25.0%). Multivariate Logistic regression analysis showed that the independent risk factors for GICs were the small intestine [odd ratio (OR) = 3.33; 95% confidence interval (CI): 1.47-9.41; P = 0.009), aggressive B-cell (OR = 0.09; 95%CI: 0.01-0.83; P = 0.033), maximum tumor diameter (OR = 1.25; 95%CI: 1.07-1.47; P = 0.005), invaded deep serous layer (OR = 3.38; 95%CI: 1.24-9.19; P = 0.017). We developed a nomogram to predict risk of GICs in aggressive PGINHL patients based on independent risk factors. The value of area under curve calculated by receiver operating characteristic curve was 0.815, and calibration curve and decision curve analysis further indicated that the prediction effect was superior. The majority of patients with GICs were given combination therapy (chemotherapy combined with surgery or radiation). Event-free survival and overall survival in GICs group were no worse than those in the No-GICs group.
CONCLUSION
The complication rate of GICs in patients with aggressive PGINHL was relatively high, particularly in PGI-DLBCL. The independent risk factors for GICs were the small intestine, PGI-TNKL, bulky tumor, and depth of invasion. A combination treatment, involving surgery, improved survival in the GICs group.
Recurrent pulmonary thromboembolism with cardiac tamponade as initial manifestations of lupus and antiphospholipid syndrome: a case report
Authors: Villanueva-Valle Julieta Sofia , Amaro-Palomo Eder Jonathan , Munive-Eyssautier Mónica Andrea , Gonzalez-Diaz Fernando , Sotelo-Soleno Adrián , Alba-Valencia Santiago , Arias-Mendoza Alexandra , Araiza-Garaygordobil Diego 
Published: October 2024

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with an important course due to systemic compromise. SLE is frequently associated with antiphospholipid syndrome, and pulmonary thromboembolism (PE) is particularly common. It is extremely rare for PE to be the initial clinical presentation and even more uncommon for it to coincide with cardiac tamponade, representing a challenge in diagnosis and management. We present a case of a 42-year-old woman with recurrent PE with severe pleural and pericardial effusion, hemodynamic instability, and cardiac tamponade. Laboratory workup revealed hypocomplementemia, leukopenia, negative SLE antibodies, and a positive lupus anticoagulant. This case emphasizes the importance of determining the etiology of PE, assessing risk classification, and implementing proper management, which are crucial for the patient's survival and outcome.
Effect of Green Supply Chain Innovation Alliance on Performance of Manufacturing Firms in Nairobi County
Authors: Ngatuny Julius , Karanja Antony , Namusonge Eric , Omwenga Jane 
Published: October 2024

Purpose: The general objective of the study was to determine influence of green supply chain innovation alliances on performance of manufacturing firms, in Nairobi County Kenya.
Methodology: The study was informed by Social Exchange Theory, Transaction Cost Theory, Resource-Based view and Resource Dependency Theory. The research design for this study was an explanatory survey research design; this is primarily a positivism approach. The population for the study will constitute manufacturing firms in Kenya. Thus, the unit of observation was 516 procurement managements from 516 manufacturing firms. The research employed stratified and simple random to select a sample of 225. This study used structured questionnaires to collect data relevant to the study. Descriptive analysis such as means, standard deviation and variance.
Findings: linear regression models showed that green supply chain innovation alliances have a positive and statistically significant influence on firm performance, highlighting their essential role in enhancing success for manufacturing firms. A strong partnership with suppliers and specialized expertise in green supply chain management are crucial for this improvement.
Unique Contribution to Theory, Practice and Policy: Therefore, the study recommends that organizations actively strengthen their green supply chain innovation alliances by establishing joint sustainability initiatives and creating regular collaboration forums with suppliers to share best practices and innovative solutions.
Impact of Temperature on Reaction Rate in Catalytic Reactions
Authors: Muchendu Ephraim 
Published: October 2024

Purpose: The aim of the study was to assess the impact of temperature on reaction rate in catalytic reactions.
Methodology: This study adopted a desk methodology. A desk study research design is commonly known as secondary data collection. This is basically collecting data from existing resources preferably because of its low cost advantage as compared to a field research. Our current study looked into already published studies and reports as the data was easily accessed through online journals and libraries.
Findings: The study indicated that as higher temperatures generally increase the rate at which reactions occur. This is due to the fact that elevated temperatures provide the reactant molecules with more kinetic energy, enabling them to collide more frequently and with greater force, which is necessary to overcome the activation energy barrier. In catalytic reactions, temperature not only accelerates the intrinsic rate of the reaction but can also affect the activity and selectivity of the catalyst. However, too high a temperature can lead to catalyst deactivation through processes such as sintering or coke formation, where the catalyst surface is altered or blocked. Thus, an optimal temperature range is crucial to balance enhanced reaction rates while maintaining catalyst integrity and performance.
Implications to Theory, Practice and Policy: Arrhenius equation, transition state theory and collision theory may be used to anchor future studies on the impact of temperature on reaction rate in catalytic reactions. In practical applications, industries should implement advanced temperature control systems to maintain optimal reaction conditions during catalytic processes. Policymakers have a critical role in shaping the landscape of catalytic reactions by developing regulatory guidelines focused on temperature management.
Environmental Sustainability: Ecological Footprint Analysis of Ibadan North, Nigeria
Authors: Sawyerr Henry , Otto Edet , Akinyemi Micheal 
Published: October 2024

The ecological implications of global development have been a primary focus in discussions surrounding sustainability. As urban development expands globally, addressing its many ecological concerns becomes imperative. However, the ecological footprint (EF) analysis of urban sustainability within the sub-Saharan region, particularly Nigeria, remains largely unexplored. Here, we used the EF indices to explore the environmental sustainability of Ibadan City, one of Nigeria’s fastest-growing urban centers. We implemented a bottom-up EF approach in the study, employing a cross-sectional design. We used an EF questionnaire to gather monthly household consumption data on food, energy, and water. We analyzed these data descriptively and methodologically using EF formulae. Findings indicate environmental sustainability, as reflected in the low EF of 0.43 gha/capita, with the energy footprint accounting for the majority (93%) at 0.4 gha/capita. In comparison, the food footprint had the lowest share (below 3%) at 0.01 gha/capita. Our findings demonstrate the significant impact of energy consumption on the overall EF, reinforcing the need for more sustainable energy solutions in urban planning, thus contributing to urban sustainability by informing urban planning and energy policy in alignment with the global sustainability drive.

Received: 17 June 2024 | Revised: 27 August 2024 | Accepted: 20 October 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
Data available on request from the corresponding author upon reasonable request.

Author Contribution Statement
Henry Sawyerr: Conceptualization, Methodology, Validation, Formal analysis, Writing - review & editing, Supervision, Funding acquisition. Edet Otto: Methodology, Formal analysis, Investigation, Writing - original draft, Funding acquisition. Micheal Akinyemi: Investigation, Visualization, Project administration, Funding acquisition.
Knowledge, attitudes and practices of a group of medical practitioners in Trinidad toward oral health during pregnancy
Authors: Ramroop Visha , Balkaran Ramaa L. , Bissoon Arlana , Kowlessar Anne , Dookeram Darren 
Published: October 2024

Abstract

Objectives
To determine the knowledge, attitudes and practices of a group of medical practitioners in Trinidad toward oral health and dental treatment during pregnancy.

Methods
One hundred and four medical practitioners practicing at both public and private institutions in Trinidad were invited to participate in this cross-sectional study over a period of 6 months. Participants were asked to complete a previously piloted self-administered 25 item questionnaire.

Results
There was 100% response rate. Mean age 34.8 years, 54.8% male, the majority (72.1%) had been practising for 10 years or less. Almost half (48.1%) thought that swollen gums were not associated with pregnancy, and an even higher percentage (60.6%) of participants felt that bleeding gums were not associated with pregnancy. The majority felt that dental examination (98.1%), tooth brushing and flossing (99%), and the use of mouthwash (95.2%) were safe during pregnancy. All respondents in this study would advise their pregnant patients to have dental examinations but fewer (94.2%) would recommend routine cleanings for these patients.

Conclusions
These data provide the first insight into the knowledge, attitudes and beliefs of medical doctors on pregnancy and oral health in the Caribbean. Dental health and pregnancy have several associations and medical doctors are suitably placed to advise their patients on the importance of the effects of dental treatment on pregnancy outcomes.
Inevitable Trends and Technologies of Libraries and Information Science
Authors: Kishore Amit , Singh Vikash Kumar 
Published: October 2024

This paper attempts to describe brief outline about latest trends, tools and technologies which are being started used in management and service areas of libraries. The emergence of ICT and its effect and impact via new technologies in libraries can be understood after going through this paper. The paper tries to pick such technologies which are becoming very famous among library and information science professionals due to its positive potential to implement and use it in LIS field. This paper tries to show how computer, mobile, internet and related technologies have capacity to go deep inside of library and information sector and having excellent power to manage libraries, library resources and can serve its users.
Web based library Services in AIIMS Library in India: an overview
Authors: Naskar Barun , Ghosh Sonia , Das Biswajit 
Published: October 2024

We are living in the virtual environment and the emerging growth and developments of internet has modified our society in every aspect. Libraries are more responsive in making users net-savvy. Not only have internet and technological developments affected the formats and sources of information, but also how and where libraries provide their services to the user. The World Wide Web (WWW) and Internet's emergence as a new medium for information storage and transmission have created an unrivalled medium for delivering information with higher speed and efficiency. All India Institute of Medical Sciences (AIIMS) are autonomous, government-funded, public medical institutions established for the advancement of medical education in India. The paper examines what web-based services, why they are important, and why they are so popular among users , as well as their benefits and drawbacks in AIIMS library, and on the basis of their website details, the evaluation of four AIIMS libraries is also emphasized.
The Impact of Internet on the Reading Habits of Undergraduate Students of Government Hamidia Arts and Commerce College, Bhopal: A Survey
Authors: Singh Amita , Kori Santosh Kumar 
Published: October 2024

Reading is a way to get better knowledge of one's own experiences and it can be an exciting journey to self-discovery. The purpose of this study is to try to understand the reading habits of undergraduate students of Government Hamidia Arts and Commerce College, Bhopal and to study the effects of internet on their reading habits. The total number of students participating in the survey is 150, and the questionnaire was distributed to them after random sampling. The results reveal whether students enjoy reading, their frequency of reading books, what genre they prefer to read, the factors that influence their reading habits, and impact of the internet (ICT) media on their reading habits.
Use of Social Media in Marketing of Library and Information Services in Academic libraries in West Bengal
Authors: Das Shraboni , Das Biswajit 
Published: October 2024

The main aim of this research paper is to find out use, advantages and problems faced by the library and information professionals in West Bengal in marketing through social media. For this study thirteen (13) college libraries in West Bengal were selected as a research sample. The findings of this research proved that most of the college libraries use WhatsApp, Facebook, Instagram, Twitter, and LinkedIn for publicity of library services. Most of the libraries use social media for marketing library resources and services, for circulating library news and events for research purpose. A face-to-face interview method are used for data collection in this study. Library professionals gives their important views and suggestions about ways of promoting library services through social media.
THE VALUE OF SCHOOL LIBRARIES IN WEST BENGAL AND THEIR CONTEMPORARY SERVICES
Authors: Ghosh Sonia , Das Biswajit 
Published: October 2024

To assist and support the school's instructional endeavours, the library is kept up. It might be useful for students' academic and extracurricular endeavours. There are primary, middle, and secondary levels in the school library. This paper has covered the goals, duties, contemporary services, and significance of secondary school libraries. In the present era, a computer system connected to a network is required for the school library. For kids and instructors to adjust to today's more advanced technology, a contemporary school library and its new services are crucial.
Grey Literature Citations by Social Science Researchers in India: A Study
Authors: Mandal Partha Sarathi , Mandal Sukumar 
Published: October 2024

Grey literature has a pivotal role in the research study. It offers valuable insights that are often overlooked in traditional academic publications. Non conventional published materials such as reports, theses, and conference proceedings are examples of grey literature. This study investigates the utilization of grey literature by social science students in India, and the findings reveal that it is widely utilized due to its accessibility, relevance to local contexts, and provision of current information. The recent publication of grey literature is used more than the earlier published literature. Researchers frequently rely on government reports and NGO publications. This study encourages researchers to cite grey literature in their research.
Zoroastrianism in India and Iran
Authors: Buhler Alexandra 
Published: October 2024

In the nineteenth century, a number of Zoroastrians emigrated from Iran to India. The subsequent importance of the cultural, religious and political ties between the Zoroastrian communities of Iran and the Zoroastrian communities of India has long been recognised. But despite this, there has been little scholarly attention paid to the changing dynamics of this transnational relationship.
This book examines the Zoroastrian community in the late Qajar and early Pahlavi period beyond the borders of Iran to trace this Parsi-Persian relationship. A major theme is the increase in philanthropy directed to the Zoroastrians of Iran by the Parsis and the involvement of the British in encouraging Parsi feelings of patriotism towards Iran. The book shows that not only were Parsis affected by events taking place in Iran, they also contributed to the broader change in attitudes towards Zoroastrians in that country.
Using a variety of original sources from Britain, India and Iran, Alexandra Buhler looks at the political, legal, and social position of Zoroastrians in Iran and how different events impacted their attitudes as well as the attitudes of Parsis towards their ancestral homeland. Of particular significance, this book shows, are the seminal years of the Iranian Constitutional Revolution (1906-11) and the rise in the glorification of the pre-Islamic past, which culminated in the state nationalism expounded by Reza Shah. These political moments had a profound impact on how Zoroastrians in India felt about their future in the country and reveal a complex web of relations between the Parsis, the Zoroastrians of Iran, and the British.