bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential of Laurencia obtusa as a substrate for the development of a probiotic Saccharomyces cerevisiae
Authors: Caf F. , Yilmaz í–. , Åžen í–zdemir N. 
Published: September 2017

Laurencia obtusa (Ceramiales, Rhodophyta) has tremendous nutritional value, being high in proteins, oligosaccharides, vitamins, essential minerals, and fatty acids, and it is a rich source of amino acids and trace elements. In this study, L. obtusa was extracted and subjected to phenolic, sugar and flavonoid analyses.The fatty acid, vitamin and phytosterol contents in Saccharomyces cerevisiae were evaluated when it was incubated with L. obtusa dry biomass. The fatty acids in the lipid extract were analysed after converting them into methyl esters using gas chromatography, and vitamin concentrations were measured using high-performance liquid chromatography (HPLC). According to the achieved results, the total fatty acid levels and vitamin contents of the S. cerevisiae prepared with algal extract increased at different rates. Our results showed that Î±-tocopherol decreased in the group in which the S. cerevisiae was added the algal extract. When compared to the control group, ergesterol increased in the group in which L. obtusa extract was added. Additionally, when compared to the control group in which L. obtusa extract was added, stearic acid (18:0), oleic acid (18:1) and linoleic acid (18:2) increased in the other groups. Palmitoleic acid (16:1) increased in the L. obtusa culture medium, but palmitic acid decreased in the L. obtusa culture medium. In conclusion, it was determined that the L. obtusa extract added to the development medium of S. cerevisiae caused differences in the synthesis of some vitamins and fatty acids.
The correlation between Pax5 deletion and patients survival in Iranian children with precursor B-cell acute lymphocytic leukemia
Authors: Moafi A. , Zojaji A. , Salehi R. , Najafi Dorcheh S. , Rahgozar S. 
Published: September 2017

Despite advances in treatment, children with acute lymphoblastic leukemia (ALL) still experience drug resistance and relapse. Several gene mutations are involved in the onset of this disease and resistance to therapy. The present study examines the incidence of IKZF1, CDKN2A/B, PAX5, EBF1, ETV6, BTG1, RB1, JAK2, and Xp22.33 gene deletions/duplications associated with pediatric ALL in Iran and investigates the possible effect of these mutations on drug resistance. Three-year disease-free survival (3DFS) was evaluated for children diagnosed with Philadelphia negative precursor-B-cell ALL hospitalized at Sayed-al-Shohada Hospital, Isfahan-Iran, from January 2009 until December 2012. DNA was extracted from bone marrow slides, and ALL correlated gene deletions and duplications were measured using Multiplex Ligation-dependent Probe Amplification (MLPA) method. The correlation between gene mutations and 3DFS was then assessed. Among the nine aforementioned investigated genes, 63% of samples showed at least one gene mutation. At least two concomitant genomic mutations were observed in 42% of samples. Pax5 deletion was the most prevalent gene mutation observed in 45% of cases, and showed significant negative impact on response to treatment. CDKN2A/B (9p21.3) gene deletion, and ETV6 (12p13.2) gene duplication also demonstrated negative effect on patient survival and contributed to a worse prognosis if concomitant with Pax5 gene deletion. ALL patients with one of the gene deletions including Pax5 and CDKN2A/B (9p21.3) or ETV6 (12p13.2) gene duplication are classified as high-risk patients and need more intensified protocols of treatment to improve their chance of survival.
Effect of sucrose concentrations on Stevia rebaudiana Bertoni tissue culture and gene expression
Authors: Ghorbani T. , Kahrizi D. , Saeidi M. , Arji I. 
Published: September 2017

Stevia rebaudiana (Bert.) Bertoni is known as sweet plant which it contains a high level of steviol glycosides in the leaves. This plant has been used from centuries ago as a sweetener for tea. One of the most important steviol glycosides is stevioside that is attractive for diabetic persons. Tissue culture is the only rapid process for the mass propagation of stevia. One of the most important factors in the medium is sucrose that is a necessary for plant growth. In the present study, we use nodal segments of the stem as explants in mediums with different sucrose concentration (50 mM, 100mM and 150mM). Several morphological traits were measured in a 28 day period. Results analysis showed a significant variation between treatments. The highest growth rate, rooting and leaf production was obtained in medium with 100mM sucrose. The correlation between measured traits was significant at the 0.01 level. To investigation of UGT74G1, UGT76G1, UGT85C2 and KS genes expression that are involved in the synthesis of SGs, RT- PCR was done with the housekeeping gene of as internal control. There were significant differences between all media. The results showed thatsucrose 100 mM containing media was more desirable than others for expression of UGT76G1 and UGT85C2 genes. Whereas, the best medium for expression of UGT74G1 was sucrose 150 mM and sucrose 50 mM for KS gene. Totally, it seems that sucrose at a concentration of 100 mMprovides the best condition for stevia growth and steviol glycosides production.
Projekt: Uniwersytet PAN
Authors: Duszyński Jerzy , Burczyński Tadeusz , Rowiński Paweł M. , Rychard Andrzej 
Published: September 2017

Instytuty Polskiej Akademii Nauk mają wśród polskich instytucji naukowych czołowy potencjał merytoryczny. W instytutach PAN w latach 2013-2016 powstało 19,7% prac afiliowanych w polskich instytucjach i umieszczonych w najbardziej prestiżowych pismach naukowych danych dziedzin (górne 10% z list pism danej dziedziny nauki uszeregowanych według rosnącego współczynnika wpływu, IF). Jest to najlepszy wynik wśród polskich instytucji akademickich. Kadra instytutów PAN zajmuje się nie tylko badaniami, ale też dydaktyką; 1607 osób (stan na 31 grudnia 2016) było na stacjonarnych studiach doktoranckich w Instytutach PAN. Stopień umiędzynarodowienia studiów w PAN (8%) jest największy wśród polskich uczelni. W związku z tym uzasadnione wydaje się powołanie Uniwersytetu PAN (UPAN), który mógłby stać się pierwszą w Polsce uczelnią badawczą. Planuje się, że docelowo kształciłoby się na nim 2,5 tys. osób, w przeważającej części studentek i studentów III stopnia. Taka liczba pozwoli na zagwarantowanie indywidualnej merytorycznej opieki każdemu studentowi, a także na wprowadzenie i przetestowanie nowatorskich programów dydaktycznych, właściwych erze Internetu i e-learningu, prowadzenia studiów online poprzez courser, studiów inter- i crossdyscyplinarnych. UPAN ma realne szanse stać się wizytówką polskiej nauki i szkolnictwa wyższego, gdyż otwarte, międzynarodowe wieloletnie programy konkursowe na pozycje: wizytujących profesorów, stażystów podoktorskich i doktorantów mogą podnieść umiędzynarodowienie zarówno kadry, jak i studentów UPAN do poziomu właściwego najlepszym uczelniom świata. Z uwagi na wielkość naszego budżetu nauki i szkolnictwa wyższego osiągnięcie takiego umiędzynarodowienia jest finansowo realne w najbliższym czasie tylko dla uczelni tak małej jak UPAN. Opisane działania będą projakościowe także dla samych instytutów PAN i istotnie podniosą ich poziom merytoryczny. Po kilku latach UPAN ma realne szanse na uplasowanie się w międzynarodowych rankingach na bardzo dobrych pozycjach, w pierwszej dwusetce, a nawet w pierwszej setce najlepszych światowych uczelni. Należy podkreślić, że warunkiem tego jest zapewnienie finansowania badań w instytutach PAN na co najmniej takim jak obecnie poziomie, uelastycznienie ich sieci, wytworzenie mechanizmów synergii pomiędzy instytutami (wspólny cel – UPAN) oraz wsparcie tego projektu długoletnim programem umiędzynarodowienia kadry i studentów.
Postulat selektywnego charakteru deregulacji w szkolnictwie wyższym
Authors: Woźnicki Jerzy 
Published: September 2017

Artykuł poświęcony jest zagadnieniom deregulacji w zakresie spraw obejmowanych przez ustawę Prawo o szkolnictwie wyższym z 2005 r. Po kolejnych nowelizacjach tej ustawy w latach 2011, 2014 i 2016 sformułowany został niebudzący wątpliwości w debacie publicznej postulat deregulacji systemu. Trzeba zadać sobie jednak pytanie, czy należy określić jej granice, a jeśli tak, to jakiej są one natury i na podstawie jakich przesłanek powinny zostać zidentyfikowane. Stanowisko autora wyraża konieczność określenia takich granic. W tekście zagadnienia te zostały poddane analizie z uwzględnieniem zakresu i charakteru pożądanych ograniczeń. Wskazane też zostały obszary, które powinny być objęte regulacjami ustawowymi. Oznacza to, że deregulacja powinna mieć charakter selektywny, pozostawiając określone kwestie poza zakresem tego działania. W artykule po wprowadzeniu w problematykę przedstawiono argumentację na rzecz niezbędności zachowania szkolnictwa wyższego jako działu regulowanego. Następnie przywołano postulat deregulacji i jej uwarunkowania, z rozróżnieniem pojęć deregulacji gramatycznej, funkcjonalnej i wykonawczej, wprowadzonych przez autora. W tym kontekście sformułowano postulat nadania deregulacji charakteru selektywnego. W ślad za odnotowaniem znaczenia konstytucyjnej zasady autonomii uczelni zaprezentowano postulowane relacje w odniesieniu do kompetencji regulacyjnych w układzie: ustawa – statut uczelni. W podsumowaniu zwrócono uwagę, że wnioskowana deregulacja z ograniczeniami wpisuje się w pożądane uwarunkowania rozwojowe instrumentarium prawnego w obszarze governance w szkolnictwie wyższym. W Dodatku przywołano fragmenty dokumentów podkreślających znaczenie dobrych praktyk w sferze stanowienia prawa dotyczącego szkolnictwa wyższego i nauki.
„Fuzjomania” akademicka. Czy Polskę czeka fala konsolidacji uniwersytetów?
Authors: Sułkowski Łukasz 
Published: September 2017

„Fuzjomania” w sektorze uczelni trwa w wielu krajach już ponad dekadę. Masowe programy fuzji realizowane są m.in. w krajach skandynawskich, we Francji, w Wielkiej Brytanii, w USA oraz w Chinach. Celem fuzji jest tworzenie światowej ligi uniwersytetów oraz racjonalizacja sieci edukacji i badań, a także restrukturyzacja służąca podwyższeniu efektywności kształcenia. W Polsce konsolidacja nie miała charakteru systemowego i nie stanowiła części polityki publicznej. Nieliczne procesy połączeń pomiędzy uczelniami dokonywały się oddolnie, bez pomocy centralnej. Prawdopodobnie jednym z negatywnych efektów braku strategicznych fuzji uczelni w Polsce jest stopniowy spadek czołowych polskich uczelni na niższe miejsca w rankingach międzynarodowych. Warto jednak postawić pytanie o wartość konsolidacji uczelni. Czy fuzje uczelni rozwijają się głównie ze względu na instrumentalną nagrodę, jaką jest awans w rankingu międzynarodowym? Warto też zadać pytanie, czy konsolidacje uczelni nie są przejawem mody, komercjalizacji edukacji, ekspansji nowego publicznego zarządzania oraz rozwoju ideologii neoliberalnej? Odpowiedzi na te pytania można szukać w badaniach prowadzonych na świecie. Dzięki rozległym doświadczeniom międzynarodowym oraz biznesowym w zakresie fuzji i przejęć możemy w Polsce przyjrzeć się wartości procesów konsolidacyjnych z perspektywy uczelni wyższych oraz społeczeństwa.
Symmetry and asymmetry of minimizers of a class of noncoercive functionals
Authors: Brock Friedemann , Croce Gisella , Guibé Olivier , Mercaldo Anna 
Published: September 2017

Abstract
In this paper we prove symmetry results for minimizers of a noncoercive functional defined on the class of Sobolev functions with zero mean value.
We prove that the minimizers are foliated Schwarz symmetric, i.e., they are axially symmetric with respect to an axis passing through the origin and nonincreasing in the polar angle from this axis.
In the two-dimensional case, we show a symmetry breaking.
Riesz potentials of Radon measures associated to reflection groups
Authors: Gallardo Léonard , Rejeb Chaabane , Sifi Mohamed 
Published: September 2017

AbstractFor a root systemRon{\mathbb{R}^{d}}and a nonnegative multiplicity functionkonR, we consider the heat kernel{p_{k}(t,x,y)}associated to the Dunkl Laplacian operator{\Delta_{k}}. For{\beta\in{]0,d+2\gamma[}}, where{\gamma=\frac{1}{2}\sum_{\alpha\in R}k(\alpha)}, we study the{\Delta_{k}}-Riesz kernel of index β, defined by{R_{k,\beta}(x,y)=\frac{1}{\Gamma(\beta/2)}\int_{0}^{+\infty}t^{{\beta/2}-1}p_% {k}(t,x,y)\,dt}, and the corresponding{\Delta_{k}}-Riesz potential{I_{k,\beta}[\mu]}of a Radon measure μ on{\mathbb{R}^{d}}. According to the values of β, we study the{\Delta_{k}}-superharmonicity of these functions, and we give some applications like the{\Delta_{k}}-Riesz measure of{I_{k,\beta}[\mu]}, the uniqueness principle and a pointwise Hedberg inequality.
Modeling framework for IoT integration of building automation systems
Authors: Schachinger Daniel , Fernbach Andreas , Kastner Wolfgang 
Published: September 2017

Abstract
Advancements within the Internet of Things are leading to a pervasive integration of different domains including also building automation systems. As a result, device functionality becomes available to a wide range of applications and users outside of the building automation domain. In this context, Web services are identified as suitable solution for machine-to-machine communication. However, a major requirement to provide necessary interoperability is the consideration of underlying semantics. Thus, this work presents a universal framework for tag-based semantic modeling and seamless integration of building automation systems via Web service-based technologies. Using the example of the KNX Web services specification, the applicability of this approach is pointed out.
Extending Brick for automated comfort diagnosis
Authors: Ploennigs Joern , Ba Amadou , Palmes Paulito 
Published: September 2017

Abstract
Modern buildings are data-rich environments that can contain thousands of IoT devices. However, most of this data is not
analyzed in order to reduce energy consumption and improve occupants' comforts. This is often due to the required large
manual effort for integrating the data into analytic systems. Semantic models allow to model the required meta-data and to
arrive at an automated integration process. This is demonstrated for the new Brick ontology, that comprehensively models
meta-data in buildings. It is extended by model concepts enabling to address challenges pertaining to physics and thermal
comfort. Moreover, this Brick ontology is further extended by reasoning approaches in order to better exploit
knowledge. As an example, the proposed approach is used to compute and diagnose virtual sensors so as to assess thermal
comfort in a real building.
Teaching Large Classes in Chinese High Schools: What Do Teachers Say and Do?
Authors: Ming Gu , Qiang Wang 
Published: September 2017

AbstractTeaching English to large classes is a common phenomenon in developing countries, and China is no exception. Such an issue has attracted attention of many researchers worldwide over the past two decades. However, such research in China has been relatively rare. This paper reports an investigation into teachers’ perceptions and practices of teaching English to large classes in Chinese schools. The study used both quantitative and qualitative methods to explore teachers’ attitude towards their perceived problems regarding teaching English to large classes, and the strategies they used to cope with large classes. Results show that an overwhelming majority of the Chinese English teachers (92.6%) hold a negative attitude towards teaching English in large classes. Pedagogical issues, management-related difficulties and psychological burden emerged as major obstacles. Despite these problems, teachers were seeking strategies to cope with the problems in their daily practices with more or less success.
Academic language in Catalan students’ research reports across levels of study
Authors: Pujol Dahme Ana M. , Selfa Moisés 
Published: September 2017

AbstractWhen students engage in a research community of practice they not only have to master academic register but also discourse features embodied in the research genre. This corpus-based study examines lexico-grammatical features and stance and engagement markers in 54 Catalan (Romance language) research reports in biology, from high school twelfth-graders and university master theses’ writers. These texts belong to the TARBUC corpus (Treballs Acadèmics de Recerca de Batxillerat i Universitat en Català) – Baccalaureate and University Academic Research Reports written in Catalan. Analyses reveal a statistically significant increase in syntactic complexity and lexical density in university writers. Furthermore, findings on interactional function indicate that marking of stance (i.e., hedges) correlates with a specific type of engagement marker (i.e., directive to argument) in university students’ texts. Self-mention is the most salient rhetorical strategy used by students, in line with the requirements of the research article published in this discipline. Finally, overall data on the distribution of interactional markers suggest that the conventions of the research article genre constrain interactional strategies from high school onwards. Results suggest that linguistic literacy, cognitive maturity and the genre’s social convention interact in a linked process in the development of a skilled writer.
A premature baby with bilateral pleural effusions, Turner syndrome (monosomy X) and myotonic dystrophy
Authors: Thean Li Jun , Koh Tieh Hee Hai Guan 
Published: September 2017

Abstract
Respiratory distress in the premature neonate has a variety of causes, some more common than others. Sometimes it may not be apparent that rare underlying conditions may be associated with common clinical presentations. In this case report, we describe an extremely premature neonate presenting with severe respiratory distress who was subsequently diagnosed with both myotonic dystrophy and Turner syndrome (monosomy X; 45, X0). A literature review correlating this neonate’s particular presentation with these diagnoses has been included.
Some courtesy formulas used by Syrian-Lebanese immigrants in Argentina
Authors: Ainciburu María Cecilia , Ramajo Cuesta Ana 
Published: September 2017

AbstractThe use of formulaic phrases has attracted considerable interest in cultural studies, but little attention has been paid to sociolinguistic issues. This paper is a study of the linguistic courtesy expressions of Syrian-Lebanese, second-generation immigrants in Argentina. Based on secret recordings, and using an interpretive approach to transfer, this research explores the relationship between courtesy formulas in Arabic and their equivalent in Spanish. Formulas containing mainly somatic elements (hands and eyes) are selected to narrow the range of meanings of the targeted expressions. The approach to transfer is interpretive; the findings show how the formulas’ structures are tailored to the requirements of different languages, and how different formulas are creatively employed to display and negotiate identities that are related to the status of immigrants in Argentina and their discursive spaces.
Health Security in Hawaii by 2050: The Physical Effects of Climate Change
Authors: Canyon Deon V. , Burkle Frederick M. , Speare Rick 
Published: September 2017

Abstract
The World Health Organization defined climate change as the most important issue for the 21st century. In 2014, the State of Hawaii called climate change “a matter of security” that directly threatens “economic systems – food, water, energy, biodiversity and health” and has called for “actionable information for local decision making.” According to the Intergovernmental Panel on Climate Change, the burden of human morbidity attributable to climate change is relatively small although not well quantified. Nevertheless, generic climate change impacts are often used to justify actions without adequate supporting local evidence. This paper analyzes Hawaii’s health risks in relation to air pollution, heat extremes, ultraviolet radiation, and weather extremes and finds that Hawaii’s natural geography, robust water, and sanitation infrastructure render the islands less vulnerable to many of the often-mentioned climate change threats. It concludes that the health security threat posed by climate change effects on Hawaii’s physical environment over the next 35 years is slight in most areas and moderate with regard to ecosystem health. Because all global communities tend to be both discrete and unique in their vulnerability, it recommends the collection of grassroots, community-based resilience data to reveal local vulnerabilities that can inform strategic statewide planning.
Neurodevelopmental outcome at the age of 4 years according to the planned mode of delivery in term breech presentation: a nationwide, population-based record linkage study
Authors: Macharey Georg , Väisänen-Tommiska Mervi , Gissler Mika , Ulander Veli-Matti , Rahkonen Leena , Nuutila Mika , Heinonen Seppo 
Published: September 2017

Abstract

Purpose:
To evaluate whether a trial of planned vaginal breech labor affects neurologic development in children.

Methods:
This is a nationwide, Finnish, population-based record linkage study. An odds ratio with 95% confidence intervals was used to estimate the relative risk that a child delivered by planned vaginal breech labor would be diagnosed with adverse neurodevelopmental outcome (cerebral palsy, epilepsy, intellectual disability, sensor neural developmental outcome, hyperactivity, speech and language problems) at the age of 4 years. The reference group were children born by planned cesarean section.

Results:
During a study period of 7 years, 8374 infants were delivered in breech position. Among them, 3907 (46.7%) had an attempted labor and 4467 (53.3%) infants were delivered by planned cesarean section. There were no differences in the neurodevelopmental outcome. In the planned vaginal labor group, 133 (3.4%) children had an abnormal neurodevelopmental outcome at the age of 4 years compared to 142 (3.2%) in the planned cesarean section group.

Conclusion:
The absolute risk of abnormal neurological outcome in breech deliveries at term was low, regardless of planned mode of birth. Planned vaginal breech labor did not increase the risk for abnormal neurological outcome compared to planned cesarean section.
Stereochemical implications toward the total synthesis of aromatic belts
Authors: Golder Matthew R. , Zakharov Lev N. , Jasti Ramesh 
Published: September 2017

Abstract
The synthesis of carbon nanotube (CNT) fragments has long captivated organic chemists, despite the simplistic, symmetric nature of the requisite achiral targets. Such molecules hold the potential to allow for the synthesis of homogeneous CNTs, rendering their properties more suitable for advanced applications in electronics and sensing. The [n]cycloparaphenylene family, comprised of molecules with para-linked phenyl rings in a contiguous macrocycles, represents a major landmark towards achieving absolute control of CNT architecture from the bottom-up. Attempts towards accessing the [n]cyclacene and [n]cyclophenacene families, both of which are comprised of double-stranded macrocyclic belts, have only recently been successful, however. These targets have been plagued by unstable, strained intermediates and stereochemical pitfalls that have largely thwarted accessing these fascinating structures. Herein, we disclose our synthetic strategy toward overcoming several stereochemical challenges en route to [n]cyclophenacenes via highly substituted [n]cycloparaphenylene precursors.