bluuebunny/crossref_metadata_2025_split huggingface dataset:
Problematic gaming exists and is an example of disordered gaming
Authors: Griffiths Mark D. , Kuss Daria J. , Lopez-Fernandez Olatz , Pontes Halley M. 
Published: August 2017

Background
The recent paper by Aarseth et al. (2016) questioned whether problematic gaming should be considered a new disorder particularly because “Gaming Disorder” (GD) has been identified as a disorder to be included in the next (11th) revision of the World Health Organization’s International Classification of Diseases (ICD-11).

Methods
This study uses contemporary literature to argue why GD should be included in the ICD-11.

Results
Aarseth and colleagues acknowledge that there is much literature (including papers by some of the authors themselves) that some individuals experience serious problems with video gaming. How can such an activity be seriously problematic yet not disordered? Similar to other addictions, gaming addiction is relatively rare and is in essence a syndrome (i.e., a condition or disorder characterized by a set of associated symptoms that tend to occur under specific circumstances). Consequently, not everyone will exhibit exactly the same set of symptoms and consequences, and this partly explains why those working in the problematic gaming field often disagree on symptomatology.

Conclusions
Research into gaming is not about pathologizing healthy entertainment, but about pathologizing excessive and problematic behaviors that cause significant psychological distress and impairment in an individual’s life. These are two related, but (ultimately) very distinct phenomena. While being aware that gaming is a pastime activity which is enjoyed non-problematically by many millions of individuals worldwide, it is concluded that problematic gaming exists and that it is an example of disordered gaming.
The relationship between gaming disorder and addiction requires a behavioral analysis
Authors: James Richard J. E. , Tunney Richard J. 
Published: August 2017

In their position paper, Aarseth et al. (2016) bring to light several timely issues concerning the categorization of gaming disorder as a form of addiction and as a discrete mental disorder. In our commentary, we welcome their caution toward this move and their discussion of the equivocal scientific data in its support and the potential negative consequences for gamers. We suggest that a more heterogeneous approach is required for understanding any behavioral addiction, as concepts from gambling appear to be more relevant for aspects of mobile gaming than for video games more generally. In addition to a greater need for clinical research, we argue that studying gaming at a different level of analysis than the epidemiological study is required to gain a meaningful understanding of the harm video games may or may not entail.
sobrevivência do ruinoso na Tragédia e na Comédia de Felipe Hirsch
Authors: Felippe Eduardo Ferraz 
Published: August 2017

Este ensaio dedica-se a analisar A tragédia latino-americana e A comédia latino-americana, de Felipe Hirsch. Trato da apropriação de prosas de ficção brasileiras voltadas a destacar a historicidade da herança do autoritarismo latino-americano em perspectiva comparada. Por meio da repetição de fragmentos, enfatiza-se o tópos da ruína, que destaca a violência e o trágico em sua leitura da prosa de ficção contemporânea.
Conference 2014: Promoting Today's Ideas for Tomorrow's Medicine: Pharmaceutical Science to Regulatory Science. An international symposium held jointly by CSPS and CC-CRS, June 10-13, 2014, Montreal, QC, Canada
Authors: (CSPS) Canadian Society for Pharmaceutical Sciences 
Published: August 2017

Plenaries and Special Presentations:Supriya Sharma, Acting Associate Assistant Deputy Minister, Health Canada: "Facing Tomorrow's Regulatory Challenges Today"Mick Bhatia, McMaster Stem Cell and Cancer Research Institute (SCC-RI): "Potential Applications of Human Stem Cells in Therapeutics"You Han Bae, University of Utah: "Current Paradigm of Cancer Nanomedicine and its Perspective - A Gap Between Experimental & Clinical Worlds"Laszlo Endrenyi, University of Toronto: CSPS Lifetime Achievement Award - "Sense and Sensibility (?) in Science"Rav Kumar, GlaxoSmithKline: CSPS Award of Leadership in Canadian Pharmaceutical Sciences - "A Bright Future for Pharmaceutical Sciences in Canada"Emmanuel Ho, University of Manitoba: GlaxoSmithKline/CSPS Early Career Award - "Development of Intravaginal Microbicides for the Prevention of HIV Infection"Building Opportunity Day:- The Life Sciences Industry in Canada: Now and the Future…- Start-up Pharma: Case Studies- Supporting Industry: Funding PanelConference Sessions:1. Early Discovery2. Latest Topics in Bioequivalence3. Successful Candidate Selection from Druggability to Regulatory Submission4. Regulatory Considerations and Analysis of Subsequent Entry Biologics5. Nanomedicine 6. Going Beyond Oral Delivery … Strategies to Enable Drugs to Reach New Targets7. New Trends in Mass Spectrometry for Drug Discovery & Development8. Biomarkers in Pharmacotherapy and Drug Development9. Application of Quality by Design (QbD) and Lifecycle Management to Analytical Procedure10. Current Topics in Drug Safety 11. Recent Trends in Material and Biomaterial Research
Cola parchycarpa K. Schum: Chemical Evaluation of Amino Acids, Vitamins and Other Nutritional Factors in Seed, Fruit Mesocarp and Epicarp
Authors: Emmanuel E. Essien  , Imaobong I. Udousoro  
Published: August 2017

Cola parchycarpa is one of the under-utilized monkey kola plants that yield edible tasty fruits. The amino acids, vitamins, mineral elements, proximate and anti-nutrients composition of the white aril, seed and fruit epicarp were evaluated using standard procedures. The total essential amino acids ranged from 31.84-55.70 g/100 g, predominated in lysine, leucine and cysteine. The fruit pulp and epicarp contained substantial amount of ascorbic acid (6.310 and 6.646 mg/100 g) and tocopherols (7.328 and 5.314 mg/100 g), respectively including vitamin B1, B2, B3, B5, B6, B9 and K1. Potassium, zinc and manganese were relatively high in the seed while calcium, magnesium and iron dominated in the fruit epicarp. The proximate analysis data of the fruit pulp and epicarp were similar except in protein and lipid content. Anti-nutritional factors (phytate, oxalates, cyanide and tannins) were below permissible limits. This is the first report on amino acids and detailed vitamins composition of C. parchycarpa. These findings indicate the rich nutritional potential of this tasty fruit and further processing into other value added products would encourage conservation and subversion of its impending extinction.
Multiscale Imaging of Gas Storage in Shales
Authors: Aljamaan Hamza , Ross Cynthia M. , Kovscek Anthony R. 
Published: August 2017

Summary
Four intact 2.54-cm-diameter cores from different shale plays (Barnett, Haynesville, Eagle Ford, and Permian Basin) were analyzed for their gas-storage capacity by use of a novel multiscale-imaging methodology spanning from centimeter to nanometer scale. Gas-storage (free and sorbed gas) capacity was investigated at the core scale with carbon dioxide (CO2) and krypton (Kr) by use of X-ray computed tomography (CT) with voxel dimensions of 190 × 190 × 1000 µm. Also, 2D tiled images were acquired with a scanning electron microscope (SEM) and stitched together to form 2.54-cm-diameter mosaics with a pixel resolution of 1.5 µm. Multiscale-image registration was then carried out to align the CT data with the SEM mosaics. Energy-dispersive spectroscopy (EDS) generated elemental spectra maps and subsequent component maps for regions with either substantial or minimal gas storage to assess the interplay of structural features (e.g., fractures) and matrix composition with respect to gas accessibility and storage.
Registration of CT scans (vacuumed and gas-filled) as well as 190-µm-resolution CT-derived gas-storage maps with 1.5-µm-resolution SEM mosaics is straight forward for samples with dense features (such as calcite-filled fractures) that are resolvable by CT imaging. Alignment methods were developed for samples lacking these features, including registration marks by use of silver paint and intermediate-resolution microCT scans with cubic voxel dimensions of 27 µm. After alignment, the relationship of enhanced storage zones with open fractures and reduced storage regions with secondary mineralization (such as nodules) is apparent for the carbonaceous samples. For the clay-rich Barnett sample, fracture-filling calcite is associated with reduced storage similar to the other samples; however, secondary carbonate cementation within the clay matrix aligns with regions with substantial Kr- and CO2-gas storage. In contrast, clay-rich matrix regions lacking secondary carbonate cementation exhibit minimal gas-storage potential. Causes for this unexpected result include reduced gas accessibility and, possibly, low organic-matter content in the clay-rich matrix compared with secondary cemented matrix.
These gas-sorption experiments prove the feasibility of dynamic core- to nanometer-scale CT/SEM/EDS image registration to improve sample characterization. To our knowledge, this is the first investigation of core-scale CO2-gas storage using multiscale imaging. CT and SEM image registration reveal spatial details regarding gas accessibility and storativity at the core scale. This work also supports the potential of carbon storage in shale formations and guides engineers toward optimal CO2-injection zones for enhanced gas recovery.
Effects of Hydrogen‐Rich Water on Fitness Parameters of Rice Plants
Authors: Liu Fang , Jiang Wanxiang , Han Weijuan , Li Junsheng , Liu Yongbo 
Published: August 2017

Core Ideas
Hydrogen‐rich water can affect the elongation of rice roots and shoots.
Hydrogen‐rich water can effect the reproductive fitness of Bt‐transgenic and conventional rice.
The effects of hydrogen‐rich water effects vary with original habitats and genetic backgrounds.
Hydrogen gas (H2) plays a crucial role in plant resistance to stresses, yet whether it affects plant growth and reproduction remains unclear. To detect the effects of H2 on plant fitness, we conducted a greenhouse experiment using hydrogen‐rich water (HW) to irrigate conventional rice (Oryza sativa L.), insect‐resistant Bt‐transgenic rice expressing Bacillus thuringiensis, and two wild rice species (O. rufipogon Griff. and O. minuta J. Presl) from six habitats. Hydrogen‐rich water inhibited the elongation of roots and shoots in conventional and transgenic rice. The impacts of HW on roots and shoots of wild rice varied with original habitats. Hydrogen‐rich water decreased the fitness parameters of conventional rice, with lower pollen radius, thousand seed weight, and the number of full seeds. For transgenic rice, HW decreased pollen radius and thousand seed weight but increased ear length and the number of full seeds. Results indicate that HW can affect plant growth and reproduction, and the effects vary with the original habitats and genetic backgrounds of plants.
Sensor‐based Nitrogen Fertilization for Midseason Rice Production in Southeast Missouri
Authors: Foster Anserd , Atwell Sam , Dunn David 
Published: August 2017

Core Ideas
Sensor‐based N management used with a nitrogen‐rich strip was a very effective decision support tool for midseason N management.
Sensor‐based N management provided opportunity to take advantage of year‐to‐year environmental variation.
Sensor‐based N management approach reduced the amount of total N applied without any yield penalty compared with the traditional practice.
Sensor‐based nitrogen (N) decision management tools have shown potential to improve N fertilizer efficiency, yield, and profitability. Small‐plot experiments were conducted to evaluate the use of sensor‐based management in guiding midseason N application decisions. Treatments were two rice (Oryza sativa L.) cultivars (Jupiter, a medium grain, and Roy J, a long grain) and eight N treatments: (i) check (no N fertilizer); (ii) 60 lb N/acre applied preflood + midseason N applied based on sensor reading (sensor‐based management); (iii) 90 lb N/acre applied preflood + midseason N applied based on sensor reading (sensor‐based management); (iv) 120 lb N/acre applied preflood; (v) 120 lb N/acre applied preflood + 30 lb N/acre applied at midseason (traditional practice); (vi) 120 lb N/acre applied preflood + midseason N applied based on sensor reading (sensor‐based management); (vii) 150 lb N/acre applied preflood; and (viii) 180 lb N/acre applied preflood (N reference strip). Grain yield and nitrogen use efficiency (NUE) were compared among N treatments. Results showed sensor‐based management for midseason application recommended lower total N application rate by 15 to 90 lb N/acre over the traditional practice. These results indicate that N fertilization made by a sensor‐based midseason recommendation can optimize yield and NUE in southeast Missouri.
Neurotransplantation Therapy and Cerebellar Reserve
Authors: Cendelin Jan , Mitoma Hiroshi , Manto Mario 
Published: August 2017

Background & Objective: Neurotransplantation has been recently the focus of interest as a
promising therapy to substitute lost cerebellar neurons and improve cerebellar ataxias. However, since
cell differentiation and synaptic formation are required to obtain a functional circuitry, highly integrated
reproduction of cerebellar anatomy is not a simple process. Rather than a genuine replacement,
recent studies have shown that grafted cells rescue surviving cells from neurodegeneration by exerting
trophic effects, supporting mitochondrial function, modulating neuroinflammation, stimulating endogenous
regenerative processes, and facilitating cerebellar compensatory properties thanks to neural
plasticity. On the other hand, accumulating clinical evidence suggests that the self-recovery capacity is
still preserved even if the cerebellum is affected by a diffuse and progressive pathology. We put forward
the period with intact recovery capacity as “restorable stage” and the notion of reversal capacity
as “cerebellar reserve”.

Conclusion:
The concept of cerebellar reserve is particularly relevant, both theoretically and practically,
to target recovery of cerebellar deficits by neurotransplantation. Reinforcing the cerebellar reserve and
prolonging the restorable stage can be envisioned as future endpoints of neurotransplantation.
Real-world comparison of treatment patterns and effectiveness of albiglutide and liraglutide
Authors: Buysman Erin K , Sikirica Mirko V , Thayer Sarah W , Bogart Michael , DuCharme Mary C , Joshi Ashish V 
Published: August 2017

Aim:
To compare medication adherence, discontinuation and glycemic control in patients receiving albiglutide versus liraglutide.
Patients & methods:
Administrative claims data and glycated hemoglobin (HbA
1c
) results were analyzed from a sample of adult health plan members with Type 2 diabetes.
Results:
Patients were matched 1:1 in the albiglutide (n = 2213) and liraglutide (n = 2213) overall cohorts and in 244 patients with HbA
1c
results from each treatment group. Mean HbA
1c
change from baseline was −1.0% for both groups. At 6 months, mean ± standard deviation adherence was 0.69 ± 0.29 versus 0.64 ± 0.29 (p < 0.001), and discontinuation was 33.2 versus 37.8% (p = 0.002) with albiglutide versus liraglutide, but these were not statistically or clinically different at 12 months.
Conclusion:
Similar treatment patterns and clinically meaningful reductions in HbA
1c
were observed for both treatments in this real-world comparison.
Using anthropometrics in designing for enhanced crew performance
Authors: Ross J.M. 
Published: August 2017

Today’s naval ship or craft designer routinely uses the principles of human factors (ergonomics) as a way to help enhance crew performance. But even though many aspects of human factors are well known, certain important categories often remain underutilized. One of these categories is anthropometrics, the study of human body dimensions and capabilities. Anthropometrics analyzes age, gender, and other data within populations of people, such as the general population of a nation or the special population of that nation’s active duty naval personnel. For the naval designer, anthropometrics helps to ensure adequate ergonomic design for the population from which the crew is drawn. The naval designer can address in a quantifiable manner issues such as lines of sight, console height and valve handle accessibility. When anthropometric principles are thus applied, the ship better fits the capabilities and limitations of the crew, resulting in enhanced crew performance.
Study of Traditional Uses of Medicinal Plants (Herbs) of Hilly Areas of Lekhnath Municipality
Authors: Dwa Om Prasad 
Published: August 2017

The present work is based on the exploration of traditional use medicinal plants ethonobotanically, of Lekhnath Municipliaty, Kaski. A general survey and study of medicinal plants, particularly wild and cultivated herbs was conducted from 1st Oct. 2012 to 30th Apr. 2013.This paper deals about 24 species of medicinal herbs belong to 21 families. Included families are Amaranthaceae, Asteraceae (4), Cannabinaceae, Caryophyllaceae, Chenopodiaceae, Commelinaceae, Crassulaceae, Cyperaceae, Dioscoreaceae, Euphorbiaceae, Labiatae, Leguminosae, liliaceae, Malvaceae, Nyctaginaceae, Oxalidaceae, Primulaceae, Scrophulariaceae, Trapaceae, Urticaceae and Zingiberaceae.This result was based on survey carried out consulting participatory techniques to collect detailed information about collection and utilization of traditional medicinal plants at that area. Important information and other details about the respective plants were collected by discussion with native inhaler, traditional medicine practitioners and villagers. Showing them the sample of the plants. Janapriya Journal of Interdisciplinary Studies Vol. 2, No.1 (December 2013), page: 82-89
Monitoring Cognitive Workload Using Vocal Tract and Voice Source Features
Authors: Magnusdottir Eydis Huld , Borsky Michal , Meier Manuela , Johannsdottir Kamilla , Gudnason Jon 
Published: August 2017

Monitoring cognitive workload from speech signals has received much attention from researchers in the past few years as it has the potential to improve performance and fidelity in human decision making. The bulk of the research has focused on classifying speech from talkers participating in cognitive workload experiments using simple reading tasks, memory span tests and the Stroop test, typically into three levels of low, medium and high cognitive workload. This study focuses on using parameters extracted from the vocal tract and the voice source components of the speech signal for cognitive workload monitoring. The experiment used in this study contains 98 participants, the levels were obtained by using a reading task and three Stroop tasks which were randomly ordered for each participant and an adequate rest time was used inbetween tasks to mitigate the effect of cognitive workload from one task affecting the subsequent one. Vocal tract features were obtained from the first three formants and voice source features were extracted using signal analysis on the inverse filtered speech signal. The results show that on their own, the vocal tract features outperform the voice source features. The MCR of 33.92% ± 1.05 was achieved with a SVM classifier. A weighted combination of vocal tract and voice source features classified with SWM classifier fused at the output level achieved the lowest MCR of 32.5%.
Magnetic Inflation and Stellar Mass. I. Revised Parameters for the Component Stars of the Kepler Low-mass Eclipsing Binary T-Cyg1-12664
Authors: Han Eunkyu , Muirhead Philip S. , Swift Jonathan J. , Baranec Christoph , Law Nicholas M. , Riddle Reed , Atkinson Dani , Mace Gregory N. , DeFelippis Daniel 
Published: August 2017

Abstract
Several low-mass eclipsing binary stars show larger than expected radii for their measured mass, metallicity, and age. One proposed mechanism for this radius inflation involves inhibited internal convection and starspots caused by strong magnetic fields. One particular eclipsing binary, T-Cyg1-12664, has proven confounding to this scenario. Çakırlı et al. measured a radius for the secondary component that is twice as large as model predictions for stars with the same mass and age, but a primary mass that is consistent with predictions. Iglesias-Marzoa et al. independently measured the radii and masses of the component stars and found that the radius of the secondary is not in fact inflated with respect to models, but that the primary is, which is consistent with the inhibited convection scenario. However, in their mass determinations, Iglesias-Marzoa et al. lacked independent radial velocity measurements for the secondary component due to the star’s faintness at optical wavelengths. The secondary component is especially interesting, as its purported mass is near the transition from partially convective to a fully convective interior. In this article, we independently determined the masses and radii of the component stars of T-Cyg1-12664 using archival Kepler data and radial velocity measurements of both component stars obtained with IGRINS on the Discovery Channel Telescope and NIRSPEC and HIRES on the Keck Telescopes. We show that neither of the component stars is inflated with respect to models. Our results are broadly consistent with modern stellar evolutionary models for main-sequence M dwarf stars and do not require inhibited convection by magnetic fields to account for the stellar radii.
Rapid Light-curve Changes and Probable Flip-flop Activity of the W UMa-type Binary V410 Aur
Authors: Luo Xia , Wang Kun , Zhang Xiaobin , Deng Licai , Luo Yangping , Luo Changqing 
Published: August 2017

Abstract
New photometric observations of a W UMa system, V410 Aur, were carried out over 10 nights from 2014 December 19 to 2015 February 8, from which four sets of light curves were obtained. The light curves show many unusual behavioral features, including changing occultation depths, transit minima, and asymmetric maxima. The four sets of light curves have been separately analyzed with the Wilson–Devinney method. The results suggest a totally eclipsing contact configuration for the system. Over a surprisingly short time span of only 52 days, the dominant spot distortion phase jumped twice between phases 0.0 and 0.5. The light-curve variations can be interpreted by the presence of two cool spots on the massive component. Based on our analysis, it is further suggested that the peculiar behavioral patterns are probably caused by the presence of two permanent, active large spots separated in longitude by about 180°, whose locations remain almost unchanged throughout. Our study demonstrates that the system has been undergoing typical flip-flop activity. We therefore conclude that V410 Aur is a W UMa-type system exhibiting flip-flop activity.