bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Family of Early English Oculists (1600-1751), With a Reappraisal of John Thomas Woolhouse (1664-1733/1734)
Authors: Leffler Christopher T , Schwartz Stephen G 
Published: September 2017

Introduction: John Thomas Woolhouse (1666-1733/1734), who practiced in Paris, was part of a family with 5 generations of English oculists. Some historians have derided him as a “charlatan” and have criticized him for adhering to the old notion that a cataract was a membrane anterior to the lens. Methods: We reviewed treatises and digital records related to Woolhouse and his family and the handwritten notes of his 1721 lecture series at the Royal Society of Medicine. Results: We have identified 5 generations of oculists in Woolhouse’s family, by the names of Atwood, Stepkins, Ivy, and Beaumont. Woolhouse taught students from across Europe. He was one of the early proponents in Europe, inspired by Asian medical practices, to perform paracentesis to release aqueous for a new condition called hydrophthalmia. In Woolhouse’s system, some of these cases probably described angle-closure glaucoma. He was the first to attach the name glaucoma to the palpably hard eye in 1707. He may also have been the first to teach that a soft eye was unlikely to recover vision. Credit for these teachings has traditionally gone to one of his students, Johannes Zacharias Platner, in 1745. Some historians have stated that he proposed iridectomy as a theoretical procedure, which was later performed by Cheselden. In fact, Woolhouse described techniques he had performed which today would be called pupilloplasty, synechiolysis, or pupillary membrane lysis. He was also a pioneer in dacryocystectomy for chronic dacryocystitis and in congenital cataract surgery. His writings from 1716 onward repeatedly (and correctly) stressed that most of the patients with visual disorders required depression of the crystalline lens (for what he called glaucoma), as opposed to removal of an anterior membrane (which he called cataract). Conclusions: Woolhouse was a bold ophthalmic innovator and teacher who made major contributions which have lasted to this day. Although he did not admit it, he ultimately adopted much of the evolving understanding of the nature of lens opacities. However, his stubborn refusal to adopt the newer semantics has detracted from a full appreciation of his contributions.
‘I have a feeling I can’t speak to anybody’: A thematic analysis of communication perspectives in people with Huntington’s disease
Authors: Zarotti Nicolò , Simpson Jane , Fletcher Ian 
Published: September 2017

Objectives This study explored the perspectives of people affected by Huntington’s disease (HD) on their own communicative abilities. Methods Qualitative semi-structured interviews were carried out with eight people with early HD. The data were analysed through thematic analysis. Results Four themes were constructed from the data, characterised by the following core topics: How HD directs and mediates communication; Regaining control to improve communication; Emotional outflows into communication and the struggle for separation; Sheltering as a way to boost confidence in communication. Discussion Separating patients’ identity as individuals from that of a person with a disease can help increase communicative control. Consistent with the general theory and model of self-regulation, patients should be allowed a wider range of choices to regain control over communication. Achieving better emotion regulation is of paramount importance for communication, and factors such as medication regimes, relationships and existing coping strategies should be strengthened. Consistent with previous research, feelings of safety and the idea of a safe place (‘sheltering’) represent an effective coping mechanism. Practical implications include the refinement of communication and relationships among clinicians, caregivers, and patients with HD by considering a wider range of medical, psychological and socio-environmental factors.
RETRACTED ARTICLE: Kindlin-2 promotes hepatocellular carcinoma invasion and metastasis by increasing Wnt/β-catenin signaling
Authors: Lin Jie , Lin Wansong , Ye Yunbin , Wang Liping , Chen Xiaoyan , Zang Shengbing , Huang Aimin 
Published: September 2017

Abstract

Background
Kindlin-2 is a member of the focal adhesion protein family that regulates invasion and metastasis in multiple malignancies; however, little is known about the role of Kindlin-2 in hepatocellular carcinoma (HCC) progression.

Methods
Immunohistochemistry was used to investigate Kindlin-2 expression in 177 pairs of human HCC and adjacent liver tissue samples. The role of Kindlin-2 in the in vitro invasion and migration of HCC cell lines was evaluated in MHCC97H, LM3 and SMMC7721 cells. Microarray expression analysis was applied to explore the molecular mechanism through which Kindlin-2 promoted HCC progression. Quantitative real-time PCR and Western blotting were performed to verify the microarray results.

Results
High Kindlin-2 expression was found to significantly correlate with aggressive HCC clinicopathological features including tumor encapsulation, microvascular invasion, extrahepatic metastasis and poor prognosis. In vitro, Kindlin-2 knockout or knockdown inhibited HCC cell adhesion, migration and invasion, while ectopic Kindlin-2 expression promoted these processes. Importantly, Kindlin-2 activated Wnt/β-catenin signaling and increased β-catenin expression, especially levels of non-phosphorylated β-catenin, as well as two Wnt/β-catenin signaling pathway targets, Axin2 and MMP7. Kindlin-2 also induced a change in the expression profile of HCC cells, suggesting the cells underwent epithelial-mesenchymal transition. For example, the expression of the epithelial marker E-cadherin was downregulated, while the mesenchymal markers Vimentin, N-cadherin and Snail were upregulated.

Conclusion
Kindlin-2 promotes HCC invasion, metastasis and epithelial-mesenchymal transition through Wnt/β-catenin signaling.
Computer vision methods for cranial sex estimation
Authors: Arigbabu Olasimbo Ayodeji , Liao Iman Yi , Abdullah Nurliza , Mohamad Noor Mohamad Helmee 
Published: September 2017

Abstract
The objective of this study is to demonstrate through empirical evaluation the potential of a number of computer vision (CV) methods for sex determination from human skull. To achieve this, six local feature representations, two feature learnings, and three classification algorithms are rigorously combined and evaluated on skull regions derived from skull partitions. Furthermore, we introduce for the first time the application of multi-kernel learning (MKL) on multiple features for sex prediction from human skull. In comparison to the classical forensic methods, the results in this study are competitive, attesting to the suitability of CV methods for sex estimation. The proposed approach is fully automatic.
Research on Polish psychotherapists – what types of patients they work with and what methods of psychotherapy they use
Authors: Szymańska Agnieszka , Grzesiuk Lidia , Suszek Hubert , Dobrenko Kamila , Rutkowska Małgorzata , Krawczyk Krzysztof 
Published: September 2017

Cel pracyZdecydowana większość badań prowadzonych w populacji psychoterapeutów dotyczy częstości (1) stosowanych specyficznych metod pracy oraz (2) kategorii korzystających z terapii pacjentów. W mniejszym stopniu analizuje natomiast powiązania między tymi dwiema grupami zmiennych. Podstawowym celem prezentowanych badań było stwierdzenie, jaka jest praktyka polskich terapeutów w zakresie łączenia metod pracy ze zróżnicowanymi diagnozami pacjentów.MetodaW badaniu uczestniczyło 1838 terapeutów deklarujących prowadzenie psychoterapii w Polsce (80% kobiet i 20% mężczyzn). Badani wypełniali - głównie drogą internetową - ankietę składającą się z pytań, których zakres dotyczył przede wszystkim działalności psychoterapeutycznej i przygotowania do jej wykonywania. W opisanym badaniu wykorzystano dwie grupy informacji z ankiety n.t. (1) metod pracy stosowanych przez psychoterapeutów oraz (2) kategorii poddawanych psychoterapii pacjentów - wyodrębnionych ze względu na rodzaj zgłaszanych problemów, diagnoz.WynikiWyniki badań ujawniły, że można wyodrębnić w Polsce trzy grupy/klasy terapeutów ze względu na sposób, w jaki łączą metody pracy psychoterapeutycznej z kategoriami prowadzonych pacjentów.WnioskiPozwalają też stwierdzić, iż większa liczba metod pracy, jakimi posługują się terapeuci, jest związana z podejmowaniem psychoterapii wobec bardziej zróżnicowanych kategorii pacjentów.
Time crimes in the garden of pleasure
Authors: Murray Shaun 
Published: September 2017

Abstract
‘Time crimes in the garden of pleasure’ is a presentation of a series of design projects developed in relation to the Vauxhall Pleasure Gardens by the River Thames in London and the Urban Islands Studio on Cockatoo Island in Sydney. Each location is filled with complex geometries from geological, historical and environmental territories. We unpack these complexities and invent new vessels for the prevailing phenomenon of pleasure.
Vauxhall Pleasure Gardens existed for 198 years from 1661 to 1859 through times of great change. The old world became new, the familiar made strange. Advances in science, technology, architecture, art, philosophy and politics brought together the near and the far, the infinitesimal and the galactic, the past and the future. The Pleasure Gardens had to become a generator of great experimentation and novelty, a place where the new could be seen and heard. At their considerable zenith they were one of the largest and most complex businesses in Britain, innovating at large scale across many fields.
Terminal_emulator
Authors: Knox Elena 
Published: September 2017

Abstract
The phrase ‘terminal identity’ has been used by theorists of cyber- and cypher-punk to explain the constitution of posthuman identity as projected by works of science fiction. I will now consider its application and potential adaptation to the complex and emerging identity constitution of non-fictive, material, humanoid robots developed in present-day research facilities around the world. Particularly, I refer herein to the realistic androids or ‘very humanlike robots’ produced by the Japan-based projects in ‘android science’. To generate humans’ affinity with these aesthetically very humanlike androids, engineers currently rely primarily on the display architecture of the human. Thus, ‘very humanlike robots’ can perhaps be gainfully thought as ‘terminal emulators’.
The architectural instrumentalist – exploring spatio-temporal interdependence in the composition of performed music and architectural space
Authors: Matthews Emma-Kate 
Published: September 2017

Abstract
Sound, space and time are inextricably linked. As an architect and musician, I am interested in the simultaneous capacities of architecture to influence the composition and experience of performed music – and of performed music to influence the composition and experience of architectural space. My architectural research project – the Augmented Instrumentalist (tAI) – sets out a methodology by which architectural spaces are understood as and designed to be instruments – as a means of replicating the unique acoustic profile of the city of Venice during the acqua alta. In tandem with the development of acoustically generative themes within my architectural research; my musical compositions actively appropriate architectural spaces as musical instruments, by responding to the acoustic qualities of specific performance spaces. When performed, my pieces exploit acoustical phenomena such as reverberance / echo and sympathetic resonance to articulate and augment musical motifs. For example, by using excessive reverberance to construct a harmonic sequence, or by suggesting a rhythm from an echo. Architectural acoustics have long had an effect on the development of musical ideas: ‘...in the old churches the walls were in fact powerful instruments which the ancients learned to play upon... [When it was discovered that] more than one tone could be heard at the same time with pleasing results, the harmonies produced by the coinciding of notes began to be regulated and used. From this partsinging developed [polyphonic music]’ (Rasmussen, 1962: 230)
This article investigates spatio-temporal interdependence between architecture and performed music within the context of my ongoing research.
The intentionally ruptured and temporal self of do-it-yourself architecture
Authors: Smith Cathy 
Published: September 2017

Abstract
This article focuses on the collapse of temporality, subjectivity and objectivity involved in particular forms of do-it-yourself (DIY) construction and their attendant discourses. Contrary to the consistent historical association of DIY with a cohered and stable self-identification, this article instead associates do-it-yourself with a nomadic and ‘non-unitary’ (Braidotti, 2002: 172) subject. As such, the ‘time crime’ committed here is the deliberate displacement of a particular chronological history of ipseity and the essentialist relations between self, time and space upon which this history is arguably founded.
Since its emergence in post-WWII North America, the DIY phenomenon has been presented as a methodology for circumventing a reliance upon mainstream, industrialized and discretized systems of production in order to create an accordant sense of worth and identity through independent self-production. Yet despite the perceived benefits of DIY, there remain historically persistent and unresolved questions concerning the phenomenon’s relation to mainstream consumerism and its attendant binding of all subjectivity to fiscal pursuit. From its earliest incarnation in post-World War II DIY in North America, through to ‘off-grid’ countercultural DIY and, more recently, the maker movement of the new Millennium; the do-it-yourselfer is frequently positioned as an ideologically consistent subject resisting institutional and economic control through project self-initiation and production. Yet the frequent reliance of self-producers on commercially-produced DIY products, materials and systems is also seen to simultaneously thwart their capacity to create ‘genuinely’ liberated selves. To explore these contradictions further, I will deploy contemporary poststructuralist and feminist accounts of subjectivity in order to trouble the conservative image of do-it-yourselfer. To this end, I will also posit my own small acts of DIY as specific instantiations of the complexities and challenges of self-production within, and in spite of the capitalist apparatus – and the architectural envelopes which contain and sustain it. By highlighting the complexities of my own DIY practice, and its potential links to consumerist behaviours, it will be argued that do-it-yourself is not only symptomatic of the conceptual schisms and temporal hybridity of particular architectural acts, but the inherent discordance of the makers themselves, professional or otherwise.
Publishing as architectural practice
Authors: Aling Mike 
Published: September 2017

Abstract
Appropriating its title from the recent collection of essays, Publishing as Artistic Practice (ed. Annette Gilbert, Sternberg Press, 2016) – in which publishing is explored as a recently appropriated form of artistic practice in itself – this article begins by asserting that, contrary to the art world, the act of publishing has always been an integral aspect of architectural practice, arguably dating back to Vitruvius, at which time the architectural publication was founded as a means of authenticating, distributing and subsequently developing architectural discourse and practice. This article focuses on architectural books – the book being architecture’s longest running, most abundant and most celebrated form of publishing – and book design in particular as a publishing practice. Although there is a considerable existing body of research canonizing the history and development of the architectural book, particularly between the mid-sixteenth and mid-twentieth centuries, the majority of this research has focused on book content rather than book design. The book is still intrinsic to the proliferation of architectural discourse, culture and the profession, but the lack of debate and development around the theories of its form and its futures is limiting the architectural book to become increasingly self-referential as a designed entity. The market-led restrictions imposed by the publishing industry are limiting the architectural book – this is the principal time crime outlined here – the design of the architectural book is in stasis due to the publishing industry: it is stuck in time. This article looks to determine how architectural book designing can be considered as relational to architectural practice, through an exploration of how book design has been theorized as a formal and material interplay and manifestation of spatial ideas – chiefly through the theories of ‘book usage’, ‘intermedia’, ‘topological’ and ‘ergodic’ literatures, ‘visual language’ semiotics and ‘metamediality’, originating from studies in literature, design, media and comics. Examples from my own architectural book design research praxis are discussed in relation to these theories, with a more thorough examination of three recent book works that are used as an armature to speculate on the potential futures of architectural book design, making and publishing practice. One hopes that this article will arouse debate and encourage more enthusiasm for book works as designed manifestations of spatial ideas. One might even go so far as declaring architectural book designs to be architectural projects.
Accommodating New Age: Understanding the needs of a growing segment
Authors: Poulston Jill , Pernecky Tomas 
Published: September 2017

Abstract
The New Age phenomenon is an under-examined research topic in tourism and hospitality. According to a 2005 Gallup survey, around three out of four Americans believe in paranormal phenomena, which are closely aligned to New Age beliefs, and indicates a unique and potentially untapped market segment. Previous research has examined the views of New Age products and services providers, but perhaps because of the heterogeneity of the New Age phenomenon, little has been done to determine New Age consumers’ needs. This study therefore explores the accommodation, food and leisure services preferences of New Age consumers, to identify potential products and services to meet their needs and conceptualize New Agers as an important market segment of future tourism.
Passionately yours: Managing emotional and spatial boundaries in lifestyle-based hospitality businesses
Authors: Ikonen Hanna-Mari 
Published: September 2017

Abstract
This article examines the boundary work done by self-employed men and women in rural areas, whose goal is to accomplish their lifestyle aspirations. Their business model is to host people, specifically dog owners, at their homes, offering a space to spend some leisure time and train in dog sports in a rural setting. For the hostentrepreneurs, the work is also their lifestyle and, therefore, the conventional boundaries between professional and personal life are constantly blurred. The article suggests that the emotionally demanding work of crossing the boundaries between private and public is motivated by their passion for their lifestyle – a desired attribute in the new economy. Although they appear to be ideal workers as per the rules of the new economy, the business and lifestyle depend on their infinite passion.
Keeping the rock rolling: Art activism and the avant-garde
Authors: Guastamacchia Nicola 
Published: September 2017

Abstract
Much recent critical and philosophical thinking on the relationship between art, politics and society chronologically grounds itself on linear understandings of the transformations of art and history. The first two decades of this century witnessed a wave of socially engaged artistic practices confused with activist strategies of political revolt. This article is an examination of the relationship between recent forms of art activism and the discontiguities of the different revolutionary claims of the history of the avant-garde. Counterposing the ideas of ‘a pure world of art’ – of art conceived as an autonomous domain from society – and of the ‘self-suppression of art in life’, or art’s identification with society, the article distinguishes recent forms of art activism from both political uses of artistic devices and artists’ individual commitment to politics in order to question what kind of art and what kind of politics art activism actually is.
Necessitating my alliance: A meditation on the Plaszow concentration camp
Authors: Spicer Gary 
Published: September 2017

Abstract
The writing that follows is a part theoretical, part-discursive response to a site of Holocaust memory and is an interaction with extracts from my ongoing journals. It is an examination of how established positions of objectivity and subjectivity as defined by the traditional academic thesis can be challenged when fused with practice and explores whether there are ways of bridging the gap between different writing genres in order for new forms to emerge. The article discusses writing as a further agency of my creative practice, its potential as an artistic form and as an additional method of critical enquiry. The article then investigates how the gesture of drawing as a projection of the body and the mediator between mind and world is an alternative vehicle to be ‘with’ and encounter the topography of the Holocaust. In relation to events as ineffable as the Holocaust, the article concludes by looking at how, by reaching for meaning through written or arts practice, we can perhaps begin to determine a contribution to what is, as Ava Hoffman describes in her book After Such Knowledge, an appropriate and measured response before, as we approach a time without living survivors, the Holocaust passes fully into history and myth.
A reflection on practice-related research – the case of radio journalism
Authors: Coleman Josephine 
Published: September 2017

Abstract
A reflection on conducting and articulating practice-related research, based on a reading of the article entitled ‘Radio journalism as research – a Ph.D. model’, by Mia Lindgren (2014) in The Radio Journal – International Studies in Broadcast & Audio Media, 12:1&2, pp. 169–182. Lindgren’s case study was her Ph.D. thesis, ‘Journalism as research: Developing radio documentary theory from practice’ (2011), Murdoch University, Perth.
YOLOCAUST Project, Shahak Shapira, Berlin, 2017
Authors: Szewczak-Harris Emma 
Published: September 2017

Abstract
Debate on (in/) appropriate behaviours at Holocaust sites has been raging ever since the field of ‘dark tourism’ (tours of sites of atrocities) rose to prominence in the 1990s. It has peaked in recent years with the appearance of the ‘Holocaust selfie’ (selfies taken at various Holocaust sites, generally designated for online publication). In 2017, Shahak Shapira launched his online project YOLOCAUST: a compendium of such selfies drawn from social media superimposed onto graphic Holocaust imagery. The project intended to shine light on the phenomenon and possibly shame its participants. This article critiques YOLOCAUST and its intentions, probing its cohesion and questioning Shapira’s success in offering a social comment on this new mode of online behaviour.