bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Golgi-associated microtubule cross-linking protein MTCL2 promotes the multipolar extension of dendrites in cerebellar granule neurons
Authors: Minekawa Mari , Suzuki Atsushi 
Published: September 2024

AbstractThe dynamic regulation of neuronal polarity is essential for establishing neural networks during brain development. The primary culture of rodent neurons recapitulates several aspects of this polarity regulation and thus provides powerful tools for revealing the cellular and molecular mechanisms underlying axon specification and neuronal migration. However, little is known about how preexisting bipolarity breaks to form multipolar dendrites. Here, we demonstrated that the Golgi-associated, microtubule (MT) cross-linking protein MTCL2 plays an essential role in this type of polarity change observed in the differentiation of cerebellar granule neurons (CGNs). MTCL2 is highly expressed in CGNs and exhibited gradual accumulation in dendrites in parallel to their polarity development. MTCL2 depletion resulted in the generation of longer and fewer dendrites by suppressing the bipolar-to-multipolar transition of dendrite extension observed in the normal polarization process. During this process, the Golgi apparatus changes its localization from the base of the preexisting bipolar neurites to the lateral or apical side of the nucleus, where it associates closely with the MT cage wrapping the nucleus. The resulting upward extension of the Golgi apparatus is tightly coupled with randomization of its position in x-y plane. Knockdown/rescue experiments demonstrated that MTCL2 promotes these changes in Golgi position in an MT- and Golgi-binding activity-dependent manner. These results suggest that MTCL2 promotes the development of multipolar short dendrites by sequestering the Golgi apparatus from the base of preexisting neurites, enabling its random movements around nuclei.
Age-dependent Changes in a Chaperone Complex in the Mouse Heart
Authors: Bhat Purnima Devaki , Nalli Aswan , Shoemaker Luke , Kwong Jennifer Q. , Krishnamurthy Prasanna , Benian Guy M. 
Published: September 2024

AbstractThe exquisitely organized sarcomere, the unit of contraction of striated muscle, is a very stable structure with a slow turnover rate of its components. The myosin chaperone UNC-45 and its co-chaperones, Hsp90 and Hsp70, are required for the initial folding of the myosin head domain and the assembly of myosin into thick filaments. There is increasing evidence that the UNC-45 chaperone system has an important role during aging to preserve sarcomere organization and myosin levels, and its decline may be a key factor in sarcopenia, the reduced skeletal muscle mass and function found in the elderly without an underlying condition. Cardiac muscle is another type of striated muscle but the role of the UNC-45 system has not yet been examined in the aging heart. Here we show that in the mouse heart, during aging, there is a decline in the levels of myosin, Unc-45b and Hsp70, but not Hsp90, and no obvious changes in sarcomere organization. In contrast, it is known that in skeletal muscle, there is a decline in both Unc-45b and Hsp90, and we show here that there is no decline in Hsp70. The decreased level of Hsp70 specifically in the heart could have broader implications than seem apparent as it could affect the folding and assembly of many other proteins in the aging heart and contribute to cardiomyopathies. Since Hsp70 mediates protein stabilization and prevents protein aggregation, its age-dependent reduction could potentially affect diseases such as amyloidosis.
Supernova-Neutrino-Boosted Dark Matter from All Galaxies
Authors: Lin Yen-Hsun , Wu Meng-Ru 
Published: September 2024

It has been recently proposed that the boosted dark matter (BDM) by supernova neutrinos (SNν) from SN1987a or from the next Galactic supernova (SN) can serve as a novel component to probe nonvanishing interaction between dark matter (DM) and the standard model leptons [Y.-H. Lin , and Y.-H. Lin , ]. In this Letter, we extend this concept and evaluate the present-day flux of SNν BDM originated from all galaxies at higher redshifts. We show that by considering this diffuse BDM (DBDM) component, the best sensitivity on the product of the energy-independent DM-ν and DM-electron cross sections, σχνσχe≃O(10−37)  cm2 for sub-MeV DM, can be obtained with large-size neutrino experiments such as Super-Kamiokande or Hyper-Kamiokande, surpassing the estimated SNν BDM bound from SN1987a. We also examine the impact due to the presence of DM spikes around the supermassive black holes in galaxies on SNν BDM and DBDM. Our results suggest that both the DBDM and the SNν BDM probes are robust to the uncertain properties of DM spikes, unless the next Galactic SN happens to occur at a location extremely close to or right behind the Galactic Center along the SN line of sight.

Published by the American Physical Society
2024
Examining the relationship between inclusive growth and tax revenue mobilization: additional evidence from sub-Saharan African countries
Authors: Adeosun Opeoluwa Adeniyi , Olomola Philip Akani , Adedokun Adebayo , Tabash Mosab I. 
Published: September 2024

PurposeThe study investigates the influence of inclusive growth on tax revenue. It validates the fiscal exchange and resource bargaining theories, which suggest that tax compliance improves when citizens perceive that their tax contributions lead to enhanced welfare and that the government negotiates with people to provide public goods and services in exchange for taxes received.Design/methodology/approachThe paper employs inclusive growth measures, including an integrated GDP and equity growth measure and alternative proxies based on GDP per person employed and Asian Development Bank (ADB) inclusive growth indicators. Using 39 sub-Saharan African countries as a sample, our analysis captures spatial interactions across these contiguous countries using the Fixed-Effect model with the Driscoll and Kraay non-parametric consistent covariance matrix and the spatial Durbin Arellano–Bond linear dynamic panel generalized method of moment (Spatial GMM) approach with an interaction weight matrix to capture interactions between countries in the region.FindingsThe paper shows that inclusive growth positively influences tax revenue in the region. This validates the fiscal exchange and resource bargaining hypotheses, demonstrating that tax compliance is positively influenced by public goods provision and the government’s ability to emphasize the necessity of taxes for service provision. It indicates that citizens are more willing to pay taxes when the government effectively promotes welfare. We find a significant positive spatial spillover effect, suggesting that inclusive growth not only boosts tax revenue within a specific country but also extends its benefits to neighboring countries, aligning with the spillover theory.Practical implicationsThe study posits that the government implements policies that guarantee effectiveness and accountability in public welfare delivery as well as sufficient tax bases and tax revenue. An inclusive growth policy that engenders GDP growth, employment and equity growth should be implemented since the rate of tax compliance of the citizens improves for every welfare provided by the government.Originality/valueThis study tests the validity of the fiscal exchange and resource bargaining theories in Sub-Saharan Africa. Accommodating spatial dependence and cross-border effects, the study sheds light on how inclusive growth impacts tax revenue across contiguous countries in the region. As such, the region should prioritize regional integration, fostering economic ties and harmonizing policies through knowledge sharing and cross-border investment.
Role of social influence in adoption of energy-efficient household systems among Pakistani consumers: a quantitative study
Authors: Sibtain Muhammad Muzummil , Hashim Muhammad , García Márquez Fausto Pedro , Baig Sajjad Ahmad , Nazam Muhammad 
Published: September 2024

PurposeThe adoption of energy-efficient systems is crucial for Pakistan to meet its growing energy demand and address its energy challenges. However, adoption of these systems in Pakistan is hindered by several barriers, including economic constraints, lack of awareness and social attitudes toward sustainable development. Therefore, the purpose of this study is to explore adoption of energy-efficient household systems and the associated social influence.Design/methodology/approachThe study incorporates social influence as a mediating factor to examine the relationships between awareness of consequences, perceived consumer effectiveness and attitudes toward the adoption of energy-efficient systems. A quantitative survey method was used to collect data from households from Faisalabad, Pakistan. A total of 203 valid questionnaires were received and data analyzed through SmartPLS 4 for structural equation modeling.FindingsThe results revealed that awareness of consequences positively impacts compliance, social identification and internalization, while perceived consumer effectiveness has a positive relationship with social identification and internalization. Moreover, the positive association of social identification and internalization with attitude were supported but relationship of compliance with attitude was unsupported.Practical implicationsThe results may also be used to develop compelling marketing campaigns focusing environmental conservation and social influence for positive attitude development.Originality/valueThe study contributes to theoretical literature by examining the empirical relationships between specific individual characteristics and societal pressure that play a critical role in shaping attitudes toward the acceptance of energy-efficient systems. Additionally, the study's findings offer actionable implications for policymakers and marketers, contributing to the development of targeted interventions for promoting sustainable consumption.
Does spirituality at work promote work-to-family enrichment among Indian female employees?
Authors: Garg Naval , Sharma Nidhi 
Published: September 2024

Purpose
Based on Indian conceptualisation of workplace spirituality, this study aims to examine the linkage between four dimensions of workplace spirituality (swadharma, authenticity, lokasangraha and sense of community) and work-to-family (WTF) enrichment. It also explored the mediating effect of psychological and social capital and the moderating effect of gratitude.

Design/methodology/approach
A sample of 387 women employees of Indian hospitality industry was collected in three waves. The collected data were analysed in three stages. Firstly, reliability, validity and multicollinearity were assessed using appropriate statistical measures like Cronbach’s alpha, composite reliability and average variance explained. Secondly, the relationship between four dimensions of workplace spirituality and WTF enrichment were examined using correlation and hierarchical regression. Several demographic variables like marital status, age, experience and income level were controlled. Thirdly, the moderating effect of gratitude and mediating effects of psychological and social capital were analysed using PROCESS macro.

Findings
The results showed adequate reliability and validity estimates. Also, four dimensions of Indian workplace spirituality were significantly related to WTF enrichment with these dimensions of workplace spirituality collectively explaining 46.8% variations in WTF enrichment. The results also concluded significant meditating effect of psychological and social capital. It also asserted significant moderating effect of gratitude.

Originality/value
The study is based on longitudinal data collected to test seven hypotheses of the study.
Whistleblowing intentions of external auditors: an application of Hofstede’s cultural dimensions theory
Authors: Anokye Fred Kwasi , Simpson Samuel Nana Yaw , Owusu Godfred Mathew Yaw , Kwakye Teddy Ossei 
Published: September 2024

Purpose
The purpose of this paper is to investigate the whistleblowing intentions of external auditors and the factors that influence their intentions.

Design/methodology/approach
Using the survey methodology, data was collected from 339 external auditors from licensed private audit firms. The partial least squares structural equation modelling technique was used to analyse the data.

Findings
The results indicate that external auditors have a greater propensity to blow the whistle on wrongdoings and they prefer to report wrongdoings using internal channels than external channels. The study further found uncertainty avoidance, masculinity and long-term orientation to be good predictors of whistleblowing intentions.

Practical implications
The findings have practical implications for human resource practitioners who seek to foster job synergy and encourage the reporting of wrongdoings. Also, it has useful implications for policymakers who seek to enhance whistleblowing activities.

Originality/value
Theoretically, this study is among the first to provide empirical support for the applicability of Hofstede’s cultural dimensions theory at the individual level within the whistleblowing discourse from an African perspective.
The effect of firm-specific determinants on export performance: the mediating role of supply chain performance
Authors: Tripathi Saswati , Roy Siddhartha Shankar , Talukder Bijoy 
Published: September 2024

PurposeThis paper analyses and assesses the effect of firm-specific determinants (FSDs) on supply-chain performance (SCP) and export performance (EP). It examines SCP’s influence on EP and its mediating effect on the relationship between FSD and EP.Design/methodology/approachThis paper develops a theoretical framework based on the resource-based view (RBV) and dynamic-capability theory to understand SCP’s role in the FSD-EP link while empirically validating using the Indian automobile industry segments (IAIS) data. The sample frame comprises all listed firms in IAIS between the financial year 2010-11 and 2021–22, with continuous data availability throughout the considered timeline. The paper employs factor analysis for dimension reduction, a panel-data-fixed-effect model to analyze the relationships, bootstrap to test the mediation effect and focus-group discussion for validating the results obtained through statistical analyses.FindingsFSD directly influences SCP’s efficiency aspect and EP. Distribution efficiency and inventory efficiency characteristics of SCP directly impact EP and completely mediate the relationship between FSD and EP.Practical implicationsThis study provides significant insights into how firms can increase EP by focusing on firm-specific and SCP-related factors. To improve EP, firms should concentrate on enhancing distribution and inventory efficiencies. Firms must focus on critical firm-level factors like age, size and raw-material import capability to increase their ability to solve SC-specific barriers and improve SCP, resulting in enhanced exports.Originality/valueThis study investigates the impacts of FSD on SCP and EP and examines the mediating effect of SCP on the relationship between FSD and EP. Such a mediating role of SCP has rarely been probed in the literature.
Integrating the SDGs into the agenda of an Argentine university
Authors: Maccagno Patricia , Goñi Verónica Andrea , Panuccio Candela Abril , Alvarez Marcela Alejandra , Diaz Yesica Daniela , Galvaliz Camila 
Published: September 2024

Purpose
The purpose of this study is to explore the incorporation of the sustainable development goals (SDGs) at the National University of Moreno (Universidad Nacional de Moreno, UNM, in Spanish), focusing on teaching and research activities, encountering difficulties from primary and secondary information sources, to integrate the SDGs, and contribute with actions for their incorporation into teaching and learning processes and research, in a newly established university.

Design/methodology/approach
To describe the implementation of the SDGs, an empirical study was conducted using a mixed methodology for data collection. Data collected from the survey were combined with information from the UNM project database for the period 2017–2022. Non-parametric methods were used to analyse both sets of data.

Findings
This study provides an initial overview of SDG implementation at UNM, allowing the identification of constraints and challenges to scale up contributions to the SDGs at UNM, as well as the generation of relevant action lines in the interaction with university's authorities.

Research limitations/implications
Conducting studies through questionnaires has limitations, similar to other cases analysed. To increase the validity of the data, prior consultations were carried out. In addition, the database of research projects was used to identify the application of the SDGs in research. However, an approximation of the current situation could be obtained.

Practical implications
Particular importance was given to the challenges encountered during the data analysis phase in relation to capacity building needs. This enabled a set of actions to be defined to bring the SDGs closer to the UNM.

Originality/value
Although the paper used methodologies already proposed by other authors, such as survey collection, its value lies in demonstrating the possibility of using them to analyse whether the SDGs are integrated into teaching and research activities in a recently founded university, where the SDGs are integrated into its principles. The analysis also complements the survey results with information from project databases, which has not yet been analysed in the literature. Based on the results, activities are designed so that the SDGs could begin to guide teaching and research activities.
Building business network relationships in the changing Chinese context: findings from Italian luxury companies
Authors: Rovai Serena 
Published: September 2024

Purpose
Through the subject of business network dynamics, this study aims to examine how business network relationships impact company entry market and development within fast growing economies as China. The paper looks at business network relationships in a fast-growing economy and provides an understanding of the relational perspectives in internationalisation of three luxury fashion companies and their entry models affected by the China context-related variables.

Design/methodology/approach
The methodology is following a qualitative approach, based on multiple case-studies research, proposing three cases of companies entering the Chinese market in the luxury and fashion industry.

Findings
The research analyses the local business network paths and how they affect the entry strategy through the socio-cultural and political players. The paper adds knowledge to studies in market entry and business networks, in the fast-growing economies area, with its new norms and values.

Originality/value
This study tries to analyse how business networks and related relationships “with Chinese characteristics” affect the market entry strategy in the internationalisation path from the perspective of the luxury fashion industry sector. In so doing it tries to provide an original further development of business network models within the new Chinese context.
When you hop, what do you hope? Evolution of success parameters for expatriates across assignments
Authors: Ray Prantika , Maheshwari Sunil Kumar 
Published: September 2024

PurposeInternational assignments are not just opportunities for career advancement but also for personal growth and exploration. This paper, by capturing the changing expectations and success parameters across the assignments, is a timely and relevant resource for individuals navigating the complexities of international careers. In addition, the paper aims to help organizations build policies for enabling successful assignments for international assignees and managers.Design/methodology/approachOur research took a unique two-pronged approach to understanding the success parameters of international assignments. We first interviewed 16 managers to understand the success parameters they set for expatriates. Then, we interviewed 19 international assignees to explore their choices and how they defined success in their international experiences.FindingsOur comprehensive research, based on 35 interviews with international assignees and their supervisors, reveals that an assignment's success evolves with different stages of the assignment, over the assignments that the assignees choose, and varies according to the intent of the mobility.Originality/valueThis paper makes a significant contribution to the field of cross-cultural management and international assignments. By discussing the evolving definition of success across various international assignments, it not only provides valuable insights for expatriates in their international careers but also to managers to build aligned policies and practices.
Multiobjective unrelated parallel machines scheduling problem with periodic maintenance activities and dependent processing times
Authors: Yaghtin Mohammad , Javid Youness 
Published: September 2024

Purpose
The purpose of this research is to address the complex multiobjective unrelated parallel machine scheduling problem with real-world constraints, including sequence-dependent setup times and periodic machine maintenance. The primary goal is to minimize total tardiness, earliness and total completion times simultaneously. This study aims to provide effective solution methods, including a Mixed-Integer Programming (MIP) model, an Epsilon-constraint method and the Nondominated Sorting Genetic Algorithm (NSGA-II), to offer valuable insights into solving large-sized instances of this challenging problem.

Design/methodology/approach
This study addresses a multiobjective unrelated parallel machine scheduling problem with sequence-dependent setup times and periodic machine maintenance activities. An MIP model is introduced to formulate the problem, and an Epsilon-constraint method is applied for a solution. To handle the NP-hard nature of the problem for larger instances, an NSGA-II is developed. The research involves the creation of 45 problem instances for computational experiments, which evaluate the performance of the algorithms in terms of proposed measures.

Findings
The research findings demonstrate the effectiveness of the proposed solution approaches for the multiobjective unrelated parallel machine scheduling problem. Computational experiments on 45 generated problem instances reveal that the NSGA-II algorithm outperforms the Epsilon-constraint method, particularly for larger instances. The algorithms successfully minimize total tardiness, earliness and total completion times, showcasing their practical applicability and efficiency in handling real-world scheduling scenarios.

Originality/value
This study contributes original value by addressing a complex multiobjective unrelated parallel machine scheduling problem with real-world constraints, including sequence-dependent setup times and periodic machine maintenance activities. The introduction of an MIP model, the application of the Epsilon-constraint method and the development of the NSGA-II algorithm offer innovative approaches to solving this NP-hard problem. The research provides valuable insights into efficient scheduling methods applicable in various industries, enhancing decision-making processes and operational efficiency.