bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting Pipeline Collapse Resistance
Authors: DeGeer Duane , Cheng J. J. Roger 
Published: October 2016

Much research has been performed over the past twenty-five years to refine our basic understanding of tubular stability, which includes bifurcation, imperfect systems, factors influencing tubular stability and post-buckling behaviour. Tubular instability resulting from load combinations is not a trivial topic, particularly when inelastic material behaviour occurs. Many influencing factors must be considered when attempting to understand (and predict) the onset of instability.
Many existing collapse predictive methods are either simplistic or involve advanced plasticity or finite element methods. Simplistic methods are typically semi-empirical, and contain a degree of uncertainty resulting in conservative collapse predictions. Nonetheless, they are generally considered satisfactory for design purposes. Advanced methods normally involve high-end calculations using specialized software programs that might not be available for general use. Therefore, a relatively easy-to-use method that accurately predicts the actual collapse resistance is, in many cases, the most desirable option.
This paper presents a collapse predictive methodology, developed from a variety of research projects performed over the last fifteen years. The prediction method, which can easily be entered into a spreadsheet program, is applicable to most forms of tubular members, including pipelines. Applicable load combinations include external pressure, axial tension and bending. An overview of the parameters influencing collapse resistance is also provided, including manufacturing history, material modelling, and tubular geometry and imperfections. Also presented is a summary of accuracy of the method to predict some test results. The test database largely contains results of collapse tests on tubular members subject to only external pressure, and axial tension with external pressure. The adaptation of the method to include external pressure with bending is summarized, and the accuracy of the prediction method is demonstrated by predicting the results of the Oman-India and Blue Stream pipeline collapse test programs, and comparing these predictions with those of other well known methodologies.
Complexity of Exercise Behavior Among Older African American Women
Authors: Kosma Maria , Buchanan David , Hondzinski Jan 
Published: October 2016

Despite the exercise benefits, disparities among diverse older adults continue to exist, where African American women have the lowest percentage of any population group in meeting national recommended activity guidelines. Drawing on the philosophical tradition of phronesis (practical reasoning) introduced by Aristotle, we studied perceptions of the exercise value among 14 older African American women. Three themes included: (1) exercise goals (e.g., effort exerted), (2) exercise reasons (e.g., health benefits, enjoyment and convenience, and activity recommendation), and (3) inactivity reasons (e.g., health issues, lack of motivation, and family responsibilities/priorities). Although most women reported being active, only three participants met the Healthy People 2020 guidelines for aerobic and muscle-strengthening activities, while two individuals were inactive. Exercise promoters should consider the values that motivate older African American women to exercise, such as the provision of accessible, nondiscriminatory exercise facilities, and not to exercise, such as concerns about neighborhood safety, in designing programs.
Development of an Electronic Version of The Children’s Self-Perceptions of Adequacy in and Predilection for Physical Activity (CSAPPA) Scale
Authors: Grant-Beuttler Marybeth , Jennings Jenifer , McCauley Christina , Dulay Robert , Grossnickle Katlyn , Kill Kerri , Hay John 
Published: October 2016

Purpose:To develop an electronic version of the Children’s Self-Perceptions of Adequacy in and Predilection for Physical Activity (eCSAPPA), which would allow individual administration to children younger than nine years of age. Methods:Fifty-four, four—nine-year-old children completed the eCSAPPA and the Test of Gross Motor Development-2 (TGMD-2). Parental measures of physical activity, and body mass index were obtained. Twenty-one participants additionally completed the paper version of the CSAPPA. Results:All children successfully completed the eCSAPPA with interclass correlation coefficients of .76 for Adequacy and .86 for Total Score. Correlations and linear predictive equations for eCSAPPA revealed the TGMD-2’s Locomotor subtest, age, and parent’s activity rating explained 28–30% of the variability in Total and Adequacy eCSAPPA scores. Predilection and Enjoyment of Physical Education (PE) scores were less stable, with the TGMD-2’s Locomotor subtest and age predicting 17% of the Predilection score and the TGMD-2’s Object Control subtest demonstrating 17% of Enjoyment of PE. Conclusion:Children ages four-nine years can feasibly complete the electronic version of the CSAPPA and results hint that self-efficacy may be more plastic in younger children. The eCSAPPA is a promising instrument allowing the exploration of young children’s development of adequacy and predilection toward physical activity as well as enjoyment of PE.
Draft Genome Sequence of Extremely Drug-Resistant Pseudomonas aeruginosa (ST357) Strain CMC_VB_PA_B22862 Isolated from a Community-Acquired Bloodstream Infection
Authors: Pragasam Agila Kumari , Yesurajan Francis , Doss C George Priya , George Biju , Devanga Ragupathi Naveen Kumar , Walia Kamini , Veeraraghavan Balaji 
Published: October 2016

ABSTRACT

Extremely drug-resistant
Pseudomonas aeruginosa
strains causing severe infections have become a serious concern across the world. Here, we report draft genome sequence of
P. aeruginosa
with an extremely drug-resistant profile isolated from a patient with community-acquired bloodstream infection in India.
High-Quality Draft Genome Sequence of Thermocrinis jamiesonii GBS1
T
Isolated from Great Boiling Spring, Nevada
Authors: Ganji Rakesh , Murugapiran Senthil K. , Ong John C. , Manoharan Namritha , Huntemann Marcel , Clum Alicia , Pillay Manoj , Palaniappan Krishnaveni , Varghese Neha , Mikhailova Natalia , Stamatis Dimitrios , Reddy T. B. K. , Ngan Chew Yee , Daum Chris , Duffy Kecia , Shapiro Nicole , Markowitz Victor , Ivanova Natalia , Kyrpides Nikos , Woyke Tanja , Dodsworth Jeremy A. , Hedlund Brian P. 
Published: October 2016

ABSTRACT

The draft genome of
Thermocrinis jamiesonii
GBS1
T
is 1,315,625 bp in 10 contigs and encodes 1,463 predicted genes. The presence of
sox
genes and various glycoside hydrolases and the absence of uptake NiFe hydrogenases (
hyaB
) are consistent with a requirement for thiosulfate and suggest the ability to use carbohydrate polymers.
Complete Genome Sequence of Streptococcus pyogenes Strain JMUB1235 Isolated from an Acute Phlegmonous Gastritis Patient
Authors: Watanabe Shinya , Sasahara Teppei , Arai Naoshi , Sasaki Kazumasa , Aiba Yoshifumi , Sato'o Yusuke , Cui Longzhu 
Published: October 2016

ABSTRACT

Acute phlegmonous gastritis is an uncommon endogenous bacterial gastritis presenting with a high mortality rate. Here, we report the complete genome sequence of an
emm
89
Streptococcus pyogenes
strain, JMUB1235, which is the causative agent of acute phlegmonous gastritis.
Draft Genome Sequence of Bacillus luciferensis Isolated from Soil
Authors: Townsley Loni , Caro Lews , Kelkar Hemant , Shank Elizabeth A. 
Published: October 2016

ABSTRACT

Bacillus luciferensis
is a Gram-positive, facultatively anaerobic, motile rod. Here, we report the first draft genome sequence, to our knowledge, of a
B. luciferensis
strain (CH01), which will provide useful information for
Bacillus
and soil bacteria research.
Draft Genome Sequence of Phytopathogenic Fungus
Fusarium fujikuroi
CF-295141, Isolated from
Pinus sylvestris
Authors: Bertoni-Mann Michele , Sánchez-Hidalgo Marina , González-Menéndez Victor , Genilloud Olga 
Published: October 2016

ABSTRACT

Here, we report the draft genome sequence of a new strain of
Fusarium fujikuroi
, isolated from
Pinus sylvestris
, which was also found to produce the mycotoxin beauvericin. The Illumina-based sequence analysis revealed an approximate genome size of 44.2 Mbp, containing 164 secondary metabolite biosynthetic clusters.
Complete Genome Sequence of
Magnetospirillum
sp. Strain XM-1, Isolated from the Xi'an City Moat, China
Authors: Wang Yinzhao , Zhang Tongwei , Lin Wei , Zhang Bingfang , Cai Yao , Yang Caiyun , Li Jinhua , Xu Huangtao , Pan Yongxin 
Published: October 2016

ABSTRACT

The magnetotactic bacterium
Magnetospirillum
sp. strain XM-1 was recently isolated from the Xi'an City moat, China. It belongs to the
Rhodospirillaceae
family in the
Alphaproteobacteria
class. Here, we report the complete genome sequence of XM-1. The genome contains a single circular chromosome of 4,825,187 bp and a plasmid of 167,290 bp.
Complete Genome Sequence of Fowl Aviadenovirus Serotype 8b Isolated in South America
Authors: Izquierdo-Lara Ray , Calderón Katherine , Chumbe Ana , Montesinos Ricardo , Montalván Ángela , González Armando E. , Icochea Eliana , Fernández-Díaz Manolo 
Published: October 2016

ABSTRACT
We present here the complete genome sequence of fowl aviadenovirus E (FAdV-E) serotype 8b strain FV211-16, isolated from chickens with inclusion body hepatitis in Peru. Genome comparisons with other FAdV-E strains revealed identities of 84.9 to 97.1% and the presence of 9 and 2 unique amino acid mutations in hexon and fiber proteins, respectively.
Genome Sequences of a Novel Recombinant Duck Circovirus in China
Authors: Sun Wenchao , Zheng Min , Cao Huihui , Lu Huijun , Wei Xiankai , Pan Yi , Zhang Hongyun , Su Jiaoxiu , Li Jun , Jin Ningyi 
Published: October 2016

ABSTRACT
In this study, YN26/2013, a novel recombinant duck circovirus (DuCV), was isolated from a Muscovy duck in Yunnan Province, southern China. The whole genome of YN26/2013 consists of 1,987 nucleotides (nt), the same genomic size as that of the DuCV-2 genotype. However, YN26/2013 shares 91.5 to 94.3% nucleotide identity similarity with previously reported type I (DuCV-1) viruses. Importantly, a novel putative recombinant event between DuCV-1 and DuCV-2 was identified as occurring within the 987- to 1111-nt region of the YN26/2013 genome.
Fault welding by pseudotachylyte formation
Authors: Mitchell Thomas M. , Toy Virginia , Di Toro Giulio , Renner Jörg , Sibson Richard H. 
Published: October 2016

Abstract
During earthquakes, melt produced by frictional heating can accumulate on slip surfaces and dramatically weaken faults by melt lubrication. Once seismic slip slows and arrests, the melt cools and solidifies to form pseudotachylytes, the presence of which is commonly used by geologists to infer earthquake slip on exhumed ancient faults. Field evidence suggests that solidified melts may weld seismic faults, resulting in subsequent seismic ruptures propagating on neighboring pseudotachylyte-free faults or joints and thus leading to long-term fault slip delocalization for successive ruptures. We performed triaxial deformation experiments on natural pseudotachylyte-bearing rocks, and show that cooled frictional melt effectively welds fault surfaces together and gives faults cohesive strength comparable to that of an intact rock. Consistent with the field-based speculations, further shear is not favored on the same slip surface, but subsequent failure is accommodated on a new subparallel fault forming on an off-fault preexisting heterogeneity. A simple model of the temperature distribution in and around a pseudotachylyte following slip cessation indicates that frictional melts cool to below their solidus in tens of seconds, implying strength recovery over a similar time scale.
Clockwise rotation of the entire Oman ophiolite occurred in a suprasubduction zone setting
Authors: Morris Antony , Meyer Matthew , Anderson Mark W. , MacLeod Christopher J. 
Published: October 2016

Abstract
The Oman ophiolite provides a natural laboratory for understanding oceanic lithospheric processes. Previous paleomagnetic and structural investigations have been used to support a model involving rotation of the ophiolite during formation at a mid-oceanic microplate. However, recent geochemical evidence indicates that the ophiolite instead formed in a nascent forearc environment, opening the potential for alternative rotation mechanisms. Central to the conundrum is the contrast between ESE to SE magnetizations and NNW magnetizations from the northern and southern ophiolitic massifs, respectively, attributed previously to either differential tectonic rotations during spreading or complete emplacement-related remagnetization of the southern massifs. Here we report new paleomagnetic data from lower crustal rocks of the southern massifs that resolve this problem. Sampling of a continuous section in Wadi Abyad reveals ENE magnetizations in the dike rooting zone at the top of the lower crust that change systematically downwards to NNW directions in underlying foliated and layered gabbros. This is consistent only with remagnetization from the base upwards, replacing early remanences in layered and foliated gabbros completely but preserving original ENE magnetizations at higher levels. Comparison with new data from Wadi Khafifah provides a positive fold test that shows that this event occurred before late Campanian structural disruption of the regional orientation of the petrologic Moho. These data show that the entire ophiolite experienced large intraoceanic clockwise rotation prior to partial remagnetization, leading to a new tectonic model in which formation, rotation, and emplacement of the ophiolite are all linked to Late Cretaceous motion of Arabia and roll-back of the Oman subduction zone.
Evaluating a community-based exercise intervention with adults living with HIV: protocol for an interrupted time series study
Authors: O'Brien Kelly K , Bayoumi Ahmed M , Solomon Patricia , Tang Ada , Murzin Kate , Chan Carusone Soo , Zobeiry Mehdi , Nayar Ayesha , Davis Aileen M 
Published: October 2016

IntroductionOur aim was to evaluate a community-based exercise (CBE) intervention with the goal of reducing disability and enhancing health for community-dwelling people living with HIV (PLWH).Methods and analysisWe will use a mixed-methods implementation science study design, including a prospective longitudinal interrupted time series study, to evaluate a CBE intervention with PLWH in Toronto, Canada. We will recruit PLWH who consider themselves medically stable and safe to participate in exercise. In the baseline phase (0–8 months), participants will be monitored bimonthly. In the intervention phase (8–14 months), participants will take part in a 24-week CBE intervention that includes aerobic, resistance, balance and flexibility exercise at the YMCA 3 times per week, with weekly supervision by a fitness instructor, and monthly educational sessions. In the follow-up phase (14–22 months), participants will be encouraged to continue to engage in unsupervised exercise 3 times per week.Quantitative assessment: We will assess cardiopulmonary fitness, strength, weight, body composition and flexibility outcomes followed by the administration of self-reported questionnaires to assess disability and contextual factor outcomes (coping, mastery, stigma, social support) bimonthly. We will use time series regression analysis to determine the level and trend of outcomes across each phase in relation to the intervention.Qualitative assessment: We will conduct a series of face-to-face interviews with a subsample of participants and recreation providers at initiation, midpoint and completion of the 24-week CBE intervention. We will explore experiences and anticipated benefits with exercise, perceived impact of CBE for PLWH and the strengths and challenges of implementing a CBE intervention. Interviews will be audio recorded and analysed thematically.Ethics and disseminationProtocol approved by the University of Toronto HIV/AIDS Research Ethics Board. Knowledge translation will occur with stakeholders in the form of presentations and publications in open access peer-reviewed journals.Trial registration numberNCT02794415; Pre-results.
Subsequent Injury Study (SInS): Improving outcomes for injured New Zealanders
Authors: Derrett Sarah , Harcombe Helen , Wyeth Emma , Davie Gabrielle , Samaranayaka Ari , Hansen Paul , Hall Gill , Cameron Ian D , Gabbe Belinda , Powell Denise , Sullivan Trudy , Wilson Suzanne , Barson Dave 
Published: October 2016

BackgroundSubsequent injury (SI) is a major contributor to disability and costs for individuals and society.AimTo identify modifiable risk factors predictive of SI and SI health and disability outcomes and costs.ObjectivesTo (1) describe the nature of SIs reported to New Zealand's no-fault injury insurer (the Accident Compensation Corporation (ACC)); (2) identify characteristics of people underaccessing ACC for SI; (3) determine factors predicting or protecting against SI; and (4) investigate outcomes for individuals, and costs to society, in relation to SI.DesignProspective cohort study.MethodsPreviously collected data will be linked including data from interviews undertaken as part of the earlier Prospective Outcomes of Injury Study (POIS), ACC electronic data and national hospitalisation data about SI. POIS participants (N=2856, including 566 Māori) were recruited via ACC's injury register following an injury serious enough to warrant compensation entitlements. We will examine SI over the following 24 months for these participants using descriptive and inferential statistics including multivariable generalised linear models and Cox's proportional hazards regression.DiscussionSubsequent Injury Study (SInS) will deliver information about the risks, protective factors and outcomes related to SI for New Zealanders. As a result of sourcing injury data from New Zealand's ‘all injury’ insurer ACC, SInS includes people who have been hospitalised and not hospitalised for injury. Consequently, SInS will provide insights that are novel internationally as other studies are usually confined to examining trauma registries, specific injuries or injured workers who are covered by a workplace insurer rather than a ‘real-world’ injury population.
Low-dose intravenous tissue plasminogen activator for acute ischaemic stroke: an alternative or a new standard?
Authors: Dong Yi , Cao Wenjie , Cheng Xin , Fang Kun , Wu Fei , Yang Lumeng , Xie Yanan , Dong Qiang 
Published: October 2016

BackgroundWith the recent publication of a large clinical trial on the use of a lower dose of intravenous (IV) tissue plasminogen activator (tPA) for acute ischaemic stroke (AIS), the concept of using a different dose has been debated. We intend to review the literature on using a lower dose of IV tPA and gain a better understanding of the impact of different IV doses on the treatment of patients with AIS.MethodsA comprehensive literature search of the related topics in PubMed, EMBASE, Web of Science and MEDLINE was carried out. Key words used include low dose IV tPA, thrombolysis, Alteplace and tPA for AIS. Findings were tabulated according to the size of the cohort studied, outcome, adverse event and level of evidence. The results of all studies using lower doses were analysed for efficacy and adverse events.ResultsFrom 1992 to 2016, there were 23 trials that included 10 950 patients published on the use of lower doses of IV tPA for AIS. Doses ranged from 0.5, 0.6, 0.75 to 0.85 mg/kg. Most were observational, retrospective and registry studies. One was a prospective open-label randomised controlled trial. 13 trials combined lower doses of IV tPA with a glycoprotein IIb/IIIa inhibitor or thrombectomy. Patients treated with lower doses of IV tPA showed a trend of lower rate of symptomatic intracranial haemorrhage and mortality at 3 months but slightly more disability.ConclusionsLower doses of IV tPA showed less haemorrhagic events but were not more effective compared with the standard dose. The optimal low dose of IV tPA remains unclear. Patients with AIS with a high risk of developing sypmtomatic intracranial haemorrhage might benefit from lower dose IV tPA, such as 0.6 mg/kg.
IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity
Authors: Chiang Sarah , Weigelt Britta , Wen Huei-Chi , Pareja Fresia , Raghavendra Ashwini , Martelotto Luciano G. , Burke Kathleen A. , Basili Thais , Li Anqi , Geyer Felipe C. , Piscuoglio Salvatore , Ng Charlotte K.Y. , Jungbluth Achim A. , Balss Jörg , Pusch Stefan , Baker Gabrielle M. , Cole Kimberly S. , von Deimling Andreas , Batten Julie M. , Marotti Jonathan D. , Soh Hwei-Choo , McCalip Benjamin L. , Serrano Jonathan , Lim Raymond S. , Siziopikou Kalliopi P. , Lu Song , Liu Xiaolong , Hammour Tarek , Brogi Edi , Snuderl Matija , Iafrate A. John , Reis-Filho Jorge S. , Schnitt Stuart J. 
Published: October 2016

Abstract
Solid papillary carcinoma with reverse polarity (SPCRP) is a rare breast cancer subtype with an obscure etiology. In this study, we sought to describe its unique histopathologic features and to identify the genetic alterations that underpin SPCRP using massively parallel whole-exome and targeted sequencing. The morphologic and immunohistochemical features of SPCRP support the invasive nature of this subtype. Ten of 13 (77%) SPCRPs harbored hotspot mutations at R172 of the isocitrate dehydrogenase IDH2, of which 8 of 10 displayed concurrent pathogenic mutations affecting PIK3CA or PIK3R1. One of the IDH2 wild-type SPCRPs harbored a TET2 Q548* truncating mutation coupled with a PIK3CA H1047R hotspot mutation. Functional studies demonstrated that IDH2 and PIK3CA hotspot mutations are likely drivers of SPCRP, resulting in its reversed nuclear polarization phenotype. Our results offer a molecular definition of SPCRP as a distinct breast cancer subtype. Concurrent IDH2 and PIK3CA mutations may help diagnose SPCRP and possibly direct effective treatment. Cancer Res; 76(24); 7118–29. ©2016 AACR.
Preclinical Evidence That 3′-Deoxy-3′-[18F]Fluorothymidine PET Can Visualize Recovery of Hematopoiesis after Gemcitabine Chemotherapy
Authors: Schelhaas Sonja , Held Annelena , Bäumer Nicole , Viel Thomas , Hermann Sven , Müller-Tidow Carsten , Jacobs Andreas H. 
Published: October 2016

Abstract
Molecular imaging with the PET tracer 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT) allows assessment of the proliferative state of organs in vivo. Although used primarily in the oncology clinic, it can also shed light on the proliferation of other tissues, as demonstrated here for monitoring hematopoietic organs that recover after myelosuppressive chemotherapy. In the NMRI nude mouse model, we observed up to a 4.5-fold increase in [18F]FLT uptake in bone marrow and spleen on days 2, 3, and 5 after treatment with gemcitabine, a chemotherapeutic agent that is powerfully myelosuppressive in the model. Specifically, we observed (i) a reduced spleen weight; (ii) reduced bone marrow cell counts and proliferation (BrdUrd flow cytometry, spleen IHC; 6 hours/day 1); and (iii) reduced leukocytes in peripheral blood (day 5). In conclusion, our results show how [18F]FLT PET can provide a powerful tool to noninvasively visualize the proliferative status of hematopoietic organs after myelosuppressive therapy. Cancer Res; 76(24); 7089–95. ©2016 AACR.