bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential benefits of mindfulness during pregnancy on maternal autonomic nervous system function and infant development
Authors: Braeken Marijke A.K.A. , Jones Alexander , Otte Renée A. , Nyklíček Ivan , Van den Bergh Bea R.H. 
Published: November 2016

AbstractMindfulness is known to decrease psychological distress. Possible benefits in pregnancy have rarely been explored. Our aim was to examine the prospective association of mindfulness with autonomic nervous system function during pregnancy and with later infant social‐emotional development. Pregnant women (N = 156) completed self‐report mindfulness and emotional distress questionnaires, and had their autonomic function assessed in their first and third trimesters, including heart rate (HR), indices of heart rate variability (HRV), preejection period (PEP), and systolic (SBP) and diastolic blood pressure (DBP). The social‐emotional development of 109 infants was assessed at 4 months of age. More mindful pregnant women had less prenatal and postnatal emotional distress (p < .001) and higher cardiac parasympathetic activity: root mean square of successive differences (RMSSD: p = .03) and high‐frequency (HF) HRV (p = .02). Between the first and third trimesters, women's overall HR increased (p < .001), and HRV (RMSSD, HF HRV, and low‐frequency (LF) HRV: p < .001) and PEP decreased (p < .001). In more mindful mothers, parasympathetic activity decreased less (RMSSD: p = .01; HF HRV: p = .03) and sympathetic activity (inversely related to PEP) increased less (PEP: p = .02) between trimesters. Their offspring displayed less negative social‐emotional behavior (p = .03) compared to offspring of less mindful mothers. Mindfulness in pregnancy was associated with ANS changes likely to be adaptive and with better social‐emotional offspring development. Interventions to increase mindfulness during pregnancy might improve maternal and offspring health, but randomized trials are needed to demonstrate this.
Poststroke QEEG informs early prognostication of cognitive impairment
Authors: Schleiger Emma , Wong Andrew , Read Stephen , Rowland Tennille , Finnigan Simon 
Published: November 2016

AbstractCognitive impairment is a common consequence of stroke, but remains difficult to predict. We investigate the ability of early QEEG assessment to inform such prediction, using binary logistic regression. Thirty‐five patients (12 female, ages 18–87) suffering middle cerebral artery, ischemic stroke were studied. Resting‐state EEG was recorded 48–239 h after symptom onset. Relative power for delta, theta, alpha, and beta bands, delta:alpha ratio, and peak alpha frequency were analyzed. Montreal Cognitive Assessment (MoCA) was administered, where possible, on day of EEG and at median 99 days (range 69–138) poststroke. Eight patients could not complete the baseline MoCA, and four the follow‐up MoCA, for varying reasons (most commonly, stroke symptoms). Fifteen patients (48%) had cognitive impairment (MoCA score ≤25) at follow‐up. One QEEG index was able to correctly predict presence/absence of cognitive impairment in 24/31 patients (77.4%), whereas predischarge MoCA did so in 23 patients. This index, relative theta frequency (4–7.5 Hz) power, was computed from only three posterior electrodes over the stroke‐affected hemisphere. Its predictive accuracy (three electrodes) was higher than that of any “global” QEEG measure (averaged over 19 electrodes). These results may signify association between poststroke alpha slowing and cognitive impairment, which may be mediated by attentional (dys)function, which warrants further investigation. Pending further studies, QEEG measure(s)—from a few electrodes—could inform early prognostication of poststroke cognitive outcomes (and clinical decisions), particularly when cognitive function cannot be adequately assessed (due to symptoms, language, or other issues) or when assessment is equivocal.
Evaluation of different fragment sizes and cryoprotectants for cryopreservation of feline testicular tissues
Authors: Macente BI , Toniollo GH , Apparicio M , Mansano CFM , Thomé HE , Canella CL , Tozato MEG , Gutierrez RR 
Published: November 2016

ContentsThis study aimed to evaluate tissue damage of feline testicles sectioned in two different sizes (0.3 or 0.5 cm3) and submitted to different cryoprotectants (propanediol or glycerol). Testicles obtained from 12 domestic cats were sectioned in 0.3 and 0.5 cm3sized pieces and immediately evaluated byTBARSand semi‐quantitatively by histomorphology. The remaining fragments were placed in cryotubes with 1 ml Egg yolk Tris EquexSTMextender containing 3% glycerol or 3% propanediol and cryopreserved by fast‐freezing technique. Frozen‐thawed fragments were also evaluated byTBARSand histomorphology. Statistical analysis was performed using one‐wayANOVAwith Student–Newmann–Keuls post hoc test, withp < .05. Fresh and cryopreserved tissues generally exhibited a similar morphology concerning detachment of cells from the basement membrane and observation of nucleoli, with a great proportion scored as 0 (no alteration). When present, alterations were slight and the morphology was considered to be good (most classified in scores 1). Pyknosis was the main anomaly observed as score 2 in 54.6% and 58.4% of 0.3‐cm3fragments cryopreserved in propanediol and glycerol, respectively (16.7% scored 2 in fresh tissue). InTBARSevaluation, 0.5‐cm3fragments cryopreserved in glycerol produced less free radical compared to the 0.3 cm3cryopreserved in glycerol or propanediol. Our results showed that glycerol was more efficient than propanediol to cryopreserve 0.5‐cm3fragments; this might be attributed to the fact that glycerol molecular weight is larger than propanediol and so its perfusion in the testicular tissue is slower.
Responsiveness of intraovarian dog follicles in vitro to epidermal growth factor and vascular endothelial growth factor depends on ovarian donor age
Authors: Thongkittidilok C , Wildt DE , Songsasen N 
Published: November 2016

ContentsWe investigated the influence of epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) on in vitro follicle development within ovarian cortices recovered from pre‐pubertal (≤6 months) versus peri‐pubertal dogs (≥10 months). Ovarian cortices were cultured for 3 or 7 days in EGF (0 or 10 ng/ml) and VEGF (0, 0.1 or 1 ng/ml) and subjected to histological and apoptosis analyses. Fresh cortices from the same dogs served as “non‐cultured controls” (NCC) and were evaluated similarly. The response of ovarian follicles to growth factors differed between pre‐pubertal versus peri‐pubertal tissues. For pre‐pubertal dogs, percentage of structurally normal follicles in cortices cultured for 3 days in low VEGF (0.1 ng/ml) and EGF alone was comparable to that of the NCC. Follicle density declined in all cultured groups even after 3 days. Primary follicle diameter in all cortices cultured for 7 days, except in low VEGF, was smaller than that of the NCC, and percentage apoptotic follicles sharply increased in all treatment groups compared to the NCC. For peri‐pubertal donors, percentages of structurally normal follicles decreased in all culture treatments at 3 and 7 days of incubation compared to the NCC. However, more normal follicles were found in cortices cultured in low VEGF and the two VEGF and EGF combinations than in the absence of growth factors or with EGF alone. Culture reduced the density of developing follicles, but follicle diameter was similar to that of the NCC. TUNEL analysis revealed that high‐VEGF (1 ng/ml) treatment protected follicles against apoptosis, with the proportion of apoptotic follicles at Day 7 being comparable to that of the NCC. The findings demonstrate that the response of ovarian cortices to growth factor supplementation varied between pre‐pubertal versus peri‐pubertal donors.
Unclassifiable interstitial lung diseases: Clinical characteristics and survival
Authors: Hyldgaard Charlotte , Bendstrup Elisabeth , Wells Athol U. , Hilberg Ole 
Published: November 2016

ABSTRACT
Background and objectiveUnclassifiable disease in chronic interstitial lung disease (ILD) is a common and challenging problem but has been insufficiently studied. The 2013 update of the international multidisciplinary classification of the idiopathic interstitial pneumonias presented a classification based on observed disease behaviour with the purpose of providing guidance to clinicians in the management of these patients. The aim of this study was to apply the new disease behaviour classification (DBC) and the previously validated ILD‐gender age physiology (GAP) score to a cohort of unclassifiable ILD patients and to assess the prognostic value of these two composite approaches.MethodsUnclassifiable ILD patients were identified from the population‐based ILD registry at Aarhus University Hospital, Denmark, that includes all ILD patients diagnosed at the department from 2003 to 2009. The DBC was assessed retrospectively based on clinical presentation and diagnostic examinations at presentation and short‐term follow‐up.ResultsUnclassifiable ILD was diagnosed in 24% of the cohort (105 of 431). Survival in unclassifiable ILD was intermediate between idiopathic pulmonary fibrosis (IPF) and non‐IPF controls (idiopathic non‐specific interstitial pneumonia (NSIP), hypersensitivity pneumonitis and connective tissue disease‐associated ILD). The DBC and the ILD‐GAP index were strong individual predictors of outcome in a dichotomized regression model (hazard ratio (HR): 6.3 (95% CI: 1.8–21.2) for the DBC and HR: 6.7 (95% CI: 2.2–20.0) for ILD‐GAP). Both approaches remained significant in a common regression model (HR: 4.5 (95% CI: 1.3–15.7) for the DBC and HR: 5.1 (95% CI: 1.3–15.7) for ILD‐GAP).ConclusionThe DBC approach showed strong prognostic value in unclassifiable ILD. The DBC and the ILD‐GAP were complementary predictors of outcome in unclassifiable ILD.
The dynamics of dining out in the 21st century: Insights from organizational theory
Authors: DeSoucey Michaela , Demetry Daphne 
Published: November 2016

AbstractThe world of restaurants—as organizations as well as indicators of social status and cultural tastes—has, thus far in the 21st century, become especially dynamic in the United States and elsewhere. Social scientists have begun to engage seriously with issues concerning germane shifts in the culinary profession and the emergence of new forms of cooking and dining out. For sociologists interested in consumption, organizations, and creative work, this offers a number of timely topics, such as restaurants' financing strategies and ownership models, the institutionalization of new culinary trends, the expanding roles of chefs, and the labor practices of upmarket restaurants. This article synthesizes recent scholarship on the modern culinary field in the United States, specifically examining three interrelated themes: tensions between concurrent demands for creativity and financial returns, new ways of catering to consumer desires for authenticity, and issues of inequality in professional kitchens. It concludes by discussing several issues facing the future of dining out, as forecast by field leaders themselves, which offer further opportunities for burgeoning sociological and organizational inquiry.
Race and critical tourism studies: An analytical literature review
Authors: Jamerson W. Trevor 
Published: November 2016

AbstractThis analytical literature review focuses on critical tourism studies and its intersections with racial analyses. The tourism industry has long relied on desires to experience a sense of Otherness to generate economic growth, which makes race a valuable heuristic site to consider ways culture and economy are intertwined in the global marketplace. Two theories of race—Omi and Winant's () racial formation and Goldberg's () racial neoliberalism—are offered as avenues through that scholars might better investigate intersections of race and tourism. Race is commodified in tourism through orienting the concept around loci of value, and different types of tourism feature more racial prominence than others. Critical tourism scholars may benefit from an increased racial awareness in their work towards providing a counternarrative to strictly business‐based tourism research. Meanwhile, race scholars might benefit from an increased understanding of ways racial difference operates within tourism, as it is a major site of negotiations of Otherness. Although racial themes are more prevalent in some types of tourism than others, the two theories provided together force us to consider ways that tourism studies might further racialize its critical inquiries.
Substance use and decision‐making in adolescent best friendship dyads: The role of popularity
Authors: de Water Erik , Burk William J. , Cillessen Antonius H. N. , Scheres Anouk 
Published: November 2016

AbstractIn adolescent best friendship dyads, we examined: (a) similarity in substance use and decision‐making; (b) associations between participants' decision‐making and their own and best friend's substance use, (c) the influence of relative popularity within the dyad on these associations. Participants (n = 172; 12–18 years) named their best friend, completed popularity ratings, and a substance use questionnaire. Computer tasks were administered to assess risk‐taking and immediate reward preferences. Reciprocated same‐sex best friendship dyads (n = 49) were distinguished on their popularity, and we controlled for age differences between dyads in the analyses. Best friends were similar in substance use and risk‐taking preferences. More popular friends' risk‐taking preferences were positively associated with alcohol use of less popular friends. These findings underscore best friendship similarity in risky behaviors, and the influence of popular friends.
Epidemiology of infections following haploidentical peripheral blood hematopoietic cell transplantation
Authors: Slade Michael , Goldsmith Scott , Romee Rizwan , DiPersio John F. , Dubberke Erik R. , Westervelt Peter , Uy Geoffrey L. , Lawrence Steven J. 
Published: November 2016

AbstractBackgroundThe use of T‐cell replete haploidentical hematopoietic cell transplant (haplo‐HCT) has increased substantially since the introduction of post‐transplant cyclophosphamide (PTCy) regimens. Limited data exist concerning infectious complications of haplo‐HCT utilizing mobilized peripheral blood (PB) hematopoietic cells.MethodsThis retrospective cohort study included all adult patients at our institution undergoing PB haplo‐HCT with PTCy between June 2009 and June 2015. Infections were microbiologically confirmed. Invasive fungal infections (IFI) classified as “proven” or “probable” by standard definitions were included.ResultsIn total, 104 patients were identified. Median follow‐up was 218 days (range: 6–1576). A total of 322 episodes of infection were recorded. Eighty‐nine percent of patients experienced at least one infection. Median time to first infection was 22 days. Patients experiencing at least one bacterial, viral, and IFI were 62%, 72%, and 6%, respectively. The majority (69%) of bacterial infections were caused by enteric organisms. Seven cases of Staphylococcus aureus infection were recorded, with one bacteremia case. Cytomegalovirus (CMV) viremia occurred in 54/71 (76%) at‐risk patients at a median time of 24 days. Sixteen (15%) patients developed CMV disease. Nineteen percent (20/104) of patients developed BK polyomavirus‐associated cystitis. Six (6%) patients experienced a total of seven IFI. Infection was the primary cause of death for 12% (6/51) of patients and was a secondary cause for 41%.ConclusionIn PB haplo‐HCT patients, a high incidence of CMV viremia and disease was observed. Infections with enteric bacteria were common. Fungal and staphylococcal infections were uncommon. Further studies are needed to compare infectious complications in haplo‐HCT with other transplant modalities.
Maternal red blood cell alloantibodies identified in blood samples obtained from Iranian pregnant women: the first population study in Iran
Authors: Shahverdi Ehsan , Moghaddam Mostafa , Gorzin Fateme 
Published: November 2016

BACKGROUNDThe objective was to determine the frequency of occurrence of alloantibodies among pregnant women in Iran.STUDY DESIGN AND METHODSThis was a prospective cross‐sectional study, which was carried out in the immunohematology reference laboratory of the Iranian Blood Transfusion Organization in Tehran, Iran, in 2008 to 2015. Screening and identification of red blood cell (RBC) alloantibodies was done on the sera of 7340 pregnant females using the standard tube method and gel column agglutination technique.RESULTSAlloantibodies were identified in the serum of 332 of the 7340 (4.5%) pregnant women. A total of 410 antibodies were detected in 332 positive maternal serum samples with no previous history of blood transfusion. Anti‐D was the most common antibody accounting for 70.5% of all the antibodies formed in D– women. The incidence of specific alloimmunization other than Rh group was 14.4%.CONCLUSIONWe concluded that the alloimmunization rate was high in comparison with wide pattern in previous studies. In Iran, like other developing countries, alloimmunization screening tests are performed only to detect anti‐D in pregnant D– women. This high rate of alloimmunization, quite possibly, is due to the fact that the majority of blood samples came from pregnant women known to have previous obstetric problems. However, we suggest that RBC antibody screening tests should be extended to all D+ women.
High COX‐2 expression in canine mast cell tumours is associated with proliferation, angiogenesis and decreased overall survival
Authors: Gregório H. , Raposo T. , Queiroga F. L. , Pires I. , Pena L. , Prada J. 
Published: November 2016

AbstractCOX‐2 overexpression is associated with several hallmarks of carcinogenesis such as proliferation, angiogenesis, invasion and metastasis. Fifty cases of canine mast cell tumours (MCT) were retrospectively evaluated and submitted to immunohistochemistry for COX‐2, CD31, Ki‐67, MAC‐387 and CD3. Furthermore its relationship with clinicopathological variables and overall survival (OS) was analysed. COX‐2 intensity (P = 0.016), but not COX‐2 extension nor score was associated with decreased OS and higher grades of malignancy according to Patnaik (P = 0.002) and Kiupel (P < 0.001) grading systems. Cox‐2 intensity was also associated with higher Ki‐67 scores (P = 0.009), higher mitotic index (P = 0.022) and higher microvascularization density (P = 0.045). No association was observed for COX‐2 intensity and CD3‐T lymphocyte (P = 0.377) and macrophage infiltration (P = 0.261) by MAC‐387 immunollabelling, suggesting an active role of COX‐2 in MCT oncogenesis mainly through proliferation and angiogenesis stimulation making it a potentially clinical relevant prognosis marker and therapeutic target.
Proof of concept of the preventive efficacy of high‐dose recombinant mono‐allergen immunotherapy in atopic dogs sensitized to the Dermatophagoides farinae allergen Der f 2
Authors: Olivry Thierry , Paps Judy S. , Dunston Stanley M. 
Published: November 2016

BackgroundAllergen immunotherapy is currently the only intervention proposed to specifically prevent clinical flares after allergen challenges. The low molecular weight Der f 2 (Df2) is a major allergen in Japanese dogs sensitized to Dermatophagoides farinae house dust mites.ObjectivesPilot, blinded, placebo‐controlled experiment testing the efficacy of subcutaneous immunotherapy (SCIT) with high doses of recombinant Df2 conjugated to the maltotriose pullulan (rDf2‐P).MethodsEight Maltese beagle atopic dogs were sensitized to rDf2 then randomized to SCIT with rDf2‐P (six dogs) or placebo (two). The immunotherapy consisted of six weekly injections of increasing doses (0.1–10.0 μg) of rDf2‐P followed by four monthly injections of 10 μg of this allergen. Epicutaneous rDf2 challenges, rDf2‐specific IgE serology and intradermal reactivity, as well as serum cytokine level measurements, were performed throughout the study.ResultsSubcutaneous injections of placebo did not alter the cutaneous reactivity after rDf2 challenge, while that of the dogs treated with rDf2‐P SCIT disappeared in five of six dogs (83%) and was reduced in one of six (17%). During SCIT maintenance, skin lesion scores were significantly lower in dogs receiving SCIT compared to those treated with placebo. This clinical improvement was accompanied by a concurrent, yet not significant, decrease in rDf2‐specific IgE serology and immediate intradermal reactivity. Cytokine serum levels were inconclusive. There were no adverse events seen with rDf2‐P SCIT.Conclusions and clinical importanceThe new mono‐allergen SCIT appears safe and effective for reducing skin lesions after allergen challenges; it deserves further testing in dogs with spontaneous atopic dermatitis.
Performance Analysis of SMES Integrated with Offshore Wind Farms to Power Systems through MT-HVDC
Authors: A. Badr Mohammed , M. Atallah Ahmed , A. Bayoumi Mona 
Published: November 2016

<p>With the increase in the development of offshore wind farm (OWF) around the world, this paper describes OWF consisting of permanent magnet synchronous generator (PMSG) wind turbines connected to Active network (AC grid) and Passive network (loads) through Multi Terminal High voltage direct current(MT-HVDC) transmission system. This paper discusses the effect of using a Superconducting Magnetic Energy Storage (SMES) unit in a hybrid power system that contains OWF. In this paper, we have aggregated 300 wind turbines of 1.5 MW PMSG using an aggregation technique (multi full aggregated model using equivalent wind speed (MFAM_EWS)). Furthermore, we have used a detector to detect any tripping of any wind turbine and substitute the shortage of power due to this loss of wind turbines immediately through SMES. The Active network in this paper should have a minimum of 150 MW power to be supplied by controlling the SMES unit (absorbing or providing power according to the system requirement). Simulation has been carried out by MATLAB/Simulink program to test the effectiveness of the SMES unit during tripping some of the wind turbines, fluctuation in wind speeds, load change and voltage dips. </p>
The Peak of the PQRST and the Trajectory Path of Each Cycle of the ECG 12-Lead Wave
Authors: Setiawidayat Sabar , Sargowo Djanggan , P. Sakti Setyawan , Andarini Sri 
Published: November 2016

<p>The objective of this present article is to describe the record of the ECG 12-lead examination in order to obtain the peaks of the P, Q, R, S and T from each cycle and also to present the Peak of the PQRST and the trajectory path of each cycle of the ECG 12- lead wave. The duration of the peak R to another is used as the period of each cycle, while the Phytagoras theorem is employed to count the trajectory path of the wave in each step. The Peak PQRST is utilized to diagnose the heart condition, and the trajectory path is the distance taken up by the impulses in the heart muscles. The discrete data from the MIT-BIH and the results of the measurement itself are employed as the data to obtain the values of the peak PQRST and the trajectory path of the wave of each cycle.</p>