bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single Cell Oxygen Mapping (SCOM) by Scanning Electrochemical Microscopy Uncovers Heterogeneous Intracellular Oxygen Consumption
Authors: Santos Carla Santana , Kowaltowski Alicia J. , Bertotti Mauro 
Published: September 2017

AbstractWe developed a highly sensitive oxygen consumption scanning microscopy system using platinized platinum disc microelectrodes. The system is capable of reliably detecting single-cell respiration, responding to classical regulators of mitochondrial oxygen consumption activity as expected. Comparisons with commercial multi-cell oxygen detection systems show that the system has comparable errors (if not smaller), with the advantage of being able to monitor inter and intra-cell heterogeneity in oxygen consumption characteristics. Our results uncover heterogeneous oxygen consumption characteristics between cells and within the same cell´s microenvironments. Single Cell Oxygen Mapping (SCOM) is thus capable of reliably studying mitochondrial oxygen consumption characteristics and heterogeneity at a single-cell level.
Preparation and chemical mechanical polishing performance of CeO2/CeF3 composite powders
Authors: Zhou Chuan , Zhu Dachuan 
Published: September 2017

This work reported a simple route for preparing CeO2/CeF3 composite powders. Cerium nitrate hexahydrate, oxalic acid dihydrate and ammonium fluoride were milled and subsequently calcined to obtain the composite powders. X‐ray diffractometer, field emission scanning electron microscope, transmission electron microscopy, zeta potential tester, and polishing test were utilised to characterise those products and study the effect of doped fluorine amount on their physicochemical characteristics and chemical mechanical polishing properties. The results show that incorporation of 7 wt% fluorine into the starting materials can change the particle morphology from large sheet for pure CeO2 into uniform spherical particles with size of 30–50 nm. The composite powder with 7 wt% fluorine exhibits great suspension stability and relatively high material removal rate. Meanwhile, this slurry facilitates obtaining smoother surface after polishing, which may be related to the changes of particle morphology and decrease in overall hardness of abrasives.
AC electrokinetics based capture of yeast cells from ultra‐fast through‐flow for sensitive detection
Authors: Yuan Quan , Islam Nazmul , Wu Jie 
Published: September 2017

This work presents a three‐dimensional multi‐level microfluidic device that enables yeast cell trapping via alternating current (AC) electrokinetics (ACEK) from a rapid through‐flow of sample fluids. ACEK is a versatile technique to control and manipulate cells and microparticles at the micro/nano‐scale. Here the trapping device works by applying an AC signal over a pair of electrode across a flow‐through channel to capture bioparticles from an ultra‐fast through‐flow. The particle capture effect by ACEK was experimentally studied by measuring the cell densities at the inlet and outlet of the micro‐channel. Both symmetric AC signal and DC biased AC signal were used to achieve cell trapping. It is found that DC biased ACEK effect is highly capable of capturing cells from a rapid through‐flow. A trapping efficiency of 56.8% has been obtained from an ultra‐fast external flow with its average velocity at 4.44 mm/s. The merits of ACEK include low‐voltage electrical operation, which is suitable for portable lab‐on‐a‐chip systems. These devices offer numerous benefits for biological applications such as medical diagnostics, detection, drug screening, and particle trapping.
High‐crystallinity and large‐grain CH3NH3PbI3 thin films for efficient TiO2 nanorod array perovskite solar cells
Authors: Li Long , Shi Chengwu , Deng Xinlian , Wang Yanqing , Ni Lingling 
Published: September 2017

The high‐crystallinity, large‐grain and full‐coverage CH3NH3PbI3 thin films are successfully prepared by converting the PbI2 ·dimethyl sulphoxide (DMSO) complex thin films at the optimum annealing temperature and time of 140°C and 10 min in the glove box with the relative humidity of 10–15%. The influence of the annealing temperature and time on the crystallinity, surface morphology, optical absorption of CH3NH3PbI3 thin films is systematically investigated and the photovoltaic performance of the corresponding TiO2 nanorod array perovskite solar cells is evaluated. The results reveal that the crystallinity of CH3NH3PbI3 thin films can be improved and their grain sizes gradually increase from 200–300 to 300–500 and 500–800 nm with the increase of the annealing temperature from 100 to 120 and 140°C. The TiO2 nanorod array perovskite solar cells with the optimum annealing temperature and time of 140°C and 10 min exhibit the best photoelectric conversion efficiency (PCE) of 16.11% and the average PCE of 15.62 ± 0.49%.
Reaction temperature‐dependent growth of ZnS nanomaterials
Authors: Liu Chang , Wu Xiang 
Published: September 2017

Zinc sulphide (ZnS) nanobelts and nanotubes with high yield are prepared by a simple chemical vapour deposition approach at different reaction temperature. The as‐prepared products are characterised by several characterisation methods such as X‐ray diffraction, scanning electron microscopy, transmission electron microscopy, Raman spectrum and photoluminescence spectrum. It shows that the as‐prepared ZnS products possess well‐hexagonal wurtzite structures. Possible growth mechanisms of ZnS nanomaterials are proposed based on nucleation and oriental attachment. Photoluminescence spectrum of ZnS nanobelts shows a blue emission peak centred at 425 nm, which could be attributed to the defects associated with oxygen vacancies. Finally, the wettability of ZnS nanobelts is also investigated by water contact angle characterisation.
Synthesis of shuttle‐shaped porous CuO in water microdroplets for increased hydrazine oxidation
Authors: Wang Li , Wang Hui 
Published: September 2017

Shuttle‐shaped, porous copper oxide (CuO) microparticles were prepared from Cu(OH)2 in a water/cyclohexane interfacial reaction followed by heat treatments at different temperatures. The CuO catalysts produced high catalytic activity and good durability for hydrazine oxidation reaction (HOR). Among all catalysts, CuO catalyst heat treated at 200°C provided the highest HOR activity with an onset potential of −0.204 V and a high oxidation peak current density of 0.87 mA cm−2 of HOR. HOR performances of the CuO catalysts correlated to their porous structure and transition of different Cu species. These findings shed light on factors influencing HOR activity of CuO catalysts.
Besser vorbeugen als heilen
Authors: Schmidt Maximilian 
Published: September 2017

Zusammenfassung
Delirprävention Das Risiko, nach einem Intensivaufenthalt zu sterben, ist bei älteren Patienten dann besonders erhöht, wenn sie ein
Delir erlitten haben. Vorrangiges Ziel sollte es daher sein, ein Delir erst gar nicht entstehen zu lassen.
Treg-specific IL-27Rα deletion uncovers a key role for IL-27 in Treg function to control autoimmunity
Authors: Do Jeongsu , Kim Dongkyun , Kim Sohee , Valentin-Torres Alice , Dvorina Nina , Jang Eunjung , Nagarajavel Vivekananthan , DeSilva Tara M. , Li Xiaoxia , Ting Angela H. , Vignali Dario A. A. , Stohlman Stephen A. , Baldwin William M. , Min Booki 
Published: September 2017

SignificanceInterleukin-27 (IL-27) can promote or antagonize inflammatory responses. However, the cellular mechanisms underlying such highly diverse roles remain unclear. It was proposed that IL-27 exerts antiinflammatory functions by directly acting on conventional CD4 T cells to induce IL-10–producing cells that are implicated in controlling inflammatory responses. Here, we have developed a Treg-specific IL-27Rα–deficient animal and observed that it is highly susceptible to autoimmune disease induction despite the presence of IL-10–producing T cells. We also show that systemic administration of IL-27 fails to attenuate ongoing inflammation in the absence of Treg expression of IL-27Rα. Therefore, IL-27 acting on Tregs plays a nonreplaceable role in controlling autoimmune inflammation, providing a rationale to develop a therapy by targeting IL-27 on Tregs.
Stability of equidimensional pseudo–single-domain magnetite over billion-year timescales
Authors: Nagy Lesleis , Williams Wyn , Muxworthy Adrian R. , Fabian Karl , Almeida Trevor P. , Conbhuí Pádraig Ó , Shcherbakov Valera P. 
Published: September 2017

Significance
When magnetic crystals form in rocks and meteorites, they can record the ancient magnetic field and retain this information over geological timescales. Scientists use these magnetic recordings to study the evolution of the Earth and the Solar System. Previous theories for the recording mechanisms of the magnetic crystals in rocks and meteorites are based on the idea that the magnetic structures within crystals are near uniform. However, from numerous studies we know this not to be true. The crystals are too large in size and display complex nonuniform “vortex” structures. In this study we have shown that vortex structures are capable of recording and retaining magnetic signals over billions of years.
Type 1 diabetes induction in humanized mice
Authors: Tan Shulian , Li Yang , Xia Jinxing , Jin Chun-Hui , Hu Zheng , Duinkerken Gaby , Li Yuying , Khosravi Maharlooei Mohsen , Chavez Estefania , Nauman Grace , Danzl Nichole , Nakayama Maki , Roep Bart O. , Sykes Megan , Yang Yong-Guang 
Published: September 2017

Significance
Type 1 diabetes (T1D) is known to be caused by immune destruction of insulin-producing β cells, but the disease pathogenesis remains poorly understood largely because of limitations in animal models to study the immunopathology. Here we established a humanized mouse T1D model, in which diabetes is driven by human T cells recognizing the HLA-DQ8–restricted insulin B chain peptide consisting of amino acids 9–23 (InsB:9–23). This study not only demonstrates the capacity of InsB:9–23-specific human CD4 T cells to initiate diabetes but also provides a preclinical humanized mouse model that has the potential to be used in studies of the immunopathogenesis and immunotherapy of T1D.
Compounding and derivation
Authors: Liceras Juana M. , Klassen Rachel 
Published: September 2017

Abstract
Inflectional affixes only adhere to the head of Noun-Noun (NN) compounds which implies that the plural of casa cuna (‘crib house’) or hombre lobo (‘werewolf’) is casa-s cuna (‘crib houses’) and hombre-s lobo (‘werewolves’) respectively, while *casa cuna-s
and *hombre lobo-s
‒ with the plural inflectional affix on the modifier ‒ are ungrammatical. There seems to be more flexibility when it comes to derivational affixes since, in principle, the evaluative diminutive affix -
ito
appears to have scope over the whole compound, regardless of whether it is attached to the head or the modifier: cas-ita cuna / casa cun-ita
and hombre-c-ito lobo / hombre lob-ito
. This would imply that the operation that results in the expression of plurality of the whole word via the inflectional affix -
s
located on the semantic argument (the head of the compound), is more categorical than the one that regulates the scope of derivational morphemes (contra Zwicky, 1985). It would also imply that Cinque’s (2005) proposal according to which modifiers can c-command Nouns may be more in line with the behaviour of derivational affixes in Spanish NN compounds. Since this is a topic that has neither been discussed by Spanish grammarians nor received attention in the psycholinguistic literature, we have administered a Picture Selection Task with NN compounds exhibiting evaluative diminutive affixes to groups of L1 Spanish and L1 English-L2 Spanish speakers. Results show that for L1 Spanish speakers it is the affix on the head that has scope over the whole compound (in line with Zwicky’s 1985 proposal) while the L2 Spanish speakers treat derivational affixes as only having scope over the element to which they are attached.
Influence of musical genres with Andean contents on the components of Peruvian national identity / Influencia de géneros musicales con contenidos andinos en los componentes de la identidad nacional peruana
Authors: Pacheco Manuel , Espinosa Agustín , Schmitz Mathias 
Published: September 2017

The purpose of this study is to analyse the influence of different musical genres with Andean influences (Huayno, Chicha and Rock/Fusion) on the components of Peruvian national identity. To this end, we enlisted the participation of 92 upper-middle-class people ( M = 19.91, SD = 1.95). The participants were randomly assigned each music genre in three experimental groups: Huayno ( n = 30), Chicha ( n = 31) and Rock/Fusion ( n = 31). The results show that Rock/Fusion is the most highly rated musical genre with the most positive influence on some stereotypical components of national identity, attitude towards music and positive emotions. In contrast, the more ‘Andeanized’ genres, especially Chicha music, are perceived more negatively and have fewer positive effects on the stereotypical components of national identity, attitude towards music and positive emotions. The discussion suggests that the influence of the musical expressions evaluated depends on the ascribed status of the social group where these expressions were originally conceived and are currently consumed.
Using Pharyngeal Teeth and Chewing Pads to Estimate Juvenile Silver Carp Total Length in the La Grange Reach, Illinois River
Authors: Lampo Eli G. , Knights Brent C. , Vallazza Jon M. , Anderson Cory A. , Rechkemmer Will T. , Solomon Levi E. , Casper Andrew F. , Pendleton Richard M. , Lamer James T. 
Published: September 2017

Abstract
The Silver Carp Hypophthalmichthys molitrix is an invasive species in the Mississippi River basin; an understanding of their vulnerability to predation as juveniles may inform control by native predators and predator enhancement (e.g., stocking). Digestion of Silver Carp prey recovered from diets makes it difficult to determine the size-classes that are most vulnerable to predation by native fishes. The objective of this study was to determine whether the sizes of the chewing pad (CP), pharyngeal teeth (PT), and pharyngeal arch (PA)—the Silver Carp structures most often found intact in predator diets—were predictive of the TL of prey Silver Carp. During 2014 and 2015, juvenile Silver Carp (n = 136; &lt;180 mm) were collected using 60-Hz pulsed-DC electrofishing and mini-fyke nets in the La Grange reach of the Illinois River. We extracted Silver Carp CPs (n = 136 fish) and PAs with PT intact (n = 129 fish) and measured CP length (CPL) and width (CPW), eight reproducible PT landmarks (PT1L–PT4L; PT1W–PT4W), and four reproducible PA landmarks (PA1–PA4) to the nearest 0.01 µm. Using simple linear regression, we found a strong predictive relationship between measurements of CP, PT, or PA and the TL of Silver Carp. The CPL (r2 = 0.94) and CPW (r2 = 0.94) had the strongest relationships with Silver Carp TL, followed by PA1 (r2 = 0.89) and PT1L (r2 = 0.87). These strong relationships suggest that all three structures could be used in diet analyses to accurately estimate Silver Carp TL and thus further our understanding of predator–prey dynamics for this high-risk invasive species.
Received December 9, 2016; accepted June 29, 2017 Published online September 6, 2017
Incorporating GPS and Mobile Radio Frequency Identification to Detect PIT-Tagged Fish and Evaluate Habitat Utilization in Streams
Authors: Richer Eric E. , Fetherman Eric R. , Kondratieff Matt C. , Barnes Taylor A. 
Published: September 2017

Abstract
The use of mobile radio frequency identification (RFID) systems to detect PIT tags has increased in support of research on fish movement, population dynamics, and habitat use. We describe the development and application of a mobile RFID system that incorporates GPS to detect PIT-tagged fish and evaluate habitat utilization in streams. The study was conducted in two distinct phases. First, development and testing of the RFID–GPS system were conducted using georeferenced, PIT-tagged rocks to evaluate detection probability and GPS accuracy. Second, the system was field deployed to estimate the abundance of PIT-tagged fish and evaluate habitat utilization. Detection probability was negatively influenced by stream width, distance from the stream center, and water depth, whereas detection probability increased with the number of passes. The GPS error between detected and surveyed positions averaged 4.5 m, with greater error observed in longitude than in latitude. Because of high capture and recapture probabilities, abundance estimation of PIT-tagged fish was not only possible but also relatively precise. All detections during field deployment were assigned habitat types using the “intersect,” “closest,” and “buffer” methods in ArcGIS. Analysis of habitat utilization was limited to two bedform classes, riffles and pools, because the average area of runs and glides was smaller than the average GPS error. More Brown Trout Salmo trutta were detected in pools (76–80%) than in riffles, and all Rainbow Trout Oncorhynchus mykiss and cutbow trout (Cutthroat Trout O. clarkii × Rainbow Trout) were detected in pools. The detection field covered more cross-sectional area in pools than in riffles, which could have influenced the analysis of habitat utilization. The influence of GPS error on habitat evaluations will depend on stream size, as erroneous habitat associations should diminish as stream size increases. The flexibility of the RFID–GPS system makes it useful for a variety of studies related to habitat utilization, fish migration, and population trends.
Received March 31, 2017; accepted August 19, 2017 Published online October 20, 2017
Comprehensive DNA microarray expression profiles of tumors in tenascin-C-knockout mice
Authors: Matsumoto Kaori , Nakai Yuji , Hoshino Masaru , Yamazaki Koki , Takioto Yoshiaki , Takadera Satoru , Nakagawa Takayuki , Nishimura Ryohei , Kusakabe Moriaki 
Published: September 2017

AbstractTenascin-C (TNC), an extracellular matrix glycoprotein, plays a pivotal role in tumor growth. However, the mechanism whereby TNC affects tumor biology remains unclear. To investigate the exact role of TNC in primary tumor growth, a mouse mammary tumor cell line, GLMT1, was first developed. Subsequently, global gene expression in GLMT1-derived tumors was compared between wild-type (WT) and TNC-knockout (TNKO) mice. Tumors in WT mice were significantly larger than those in TNKO mice. DNA microarray analysis revealed 447 up and 667 downregulated in the tumors inoculated into TNKO mice as compared to tumors in WT mice. Validation by quantitative gene expression analysis showed that Tnc, Cxcl1, Cxcl2, and Cxcr2 were significantly upregulated in WT mice. We hypothesize that TNC stimulates the CXCL1/2-CXCR2 pathway involved in cancer cell proliferation.
Viewpoints and points of view: situating symbolic boundary drawing in social space
Authors: Jarness Vegard 
Published: September 2017

ABSTRACT
This article demonstrates how Pierre Bourdieu's concept of social space and Michèle Lamont's concept of symbolic boundaries can be fruitfully combined in cultural-stratification research. Focusing on the case of Stavanger, Norway, the analysis also shows how Multiple Correspondence Analysis is compatible with other research techniques, such as qualitative in-depth interviews. The approach adopted provides a practical application of Bourdieu's double reading of social relations. It combines the first, objective moment of situating 46 individuals subjected to qualitative interviews in the local social space (i.e. a system of relations between individuals’ possessions of cultural and economic capital) with the second, subjective moment of mapping the interviewees’ evaluations and classifications of other people's lifestyles. It is shown how intertwinements of various discursive repertoires of evaluation (cultural-aesthetical, moral-political and socio-economic) work in both contradictive and reinforcing ways to construct symbolic boundaries between classes and class fractions. The findings draw attention to both the capital volume and the capital composition dimensions of social space in that symbolic boundary drawing takes on different forms along these dimensions.
An automated tool for obtaining QSAR-ready series of compounds using semantic web technologies
Authors: López-Massaguer Oriol , Sanz Ferran , Pastor Manuel 
Published: September 2017

Abstract

Summary
We describe an application (Collector) for obtaining series of compounds annotated with bioactivity data, ready to be used for the development of quantitative structure-activity relationships (QSAR) models. The tool extracts data from the ‘Open Pharmacological Space’ (OPS) developed by the Open PHACTS project, using as input a valid name of the biological target. Collector uses the OPS ontologies for expanding the query using all known target synonyms and extracts compounds with bioactivity data against the target from multiple sources. The extracted data can be filtered to retain only drug-like compounds and the bioactivities can be automatically summarised to assign a single value per compound, yielding data ready to be used for QSAR modeling. The data obtained is locally stored facilitating the traceability and auditability of the process. Collector was used successfully for the development of models for toxicity endpoints within the eTOX project.

Availability and implementation
The software is available at http://phi.upf.edu/collector. The source code is located at https://github.com/phi-grib/Collector and is free for use under the GPL3 license. The web version is hosted at http://collector.upf.edu/.

Supplementary information
Supplementary data are available at Bioinformatics online.
Age bimodality in the central region of pseudo-bulges in S0 galaxies
Authors: Mishra Preetish K. , Barway Sudhanshu , Wadadekar Yogesh 
Published: September 2017

Abstract
We present evidence for bimodal stellar age distribution of pseudo-bulges of S0 galaxies as probed by the Dn(4000) index. We do not observe any bimodality in age distribution for pseudo-bulges in spiral galaxies. Our sample is flux limited and contains 2067 S0 and 2630 spiral galaxies drawn from the Sloan Digital Sky Survey. We identify pseudo-bulges in S0 and spiral galaxies, based on the position of the bulge on the Kormendy diagram and their central velocity dispersion. Dividing the pseudo-bulges of S0 galaxies into those containing old and young stellar populations, we study the connection between global star formation and pseudo-bulge age on the u − r colour–mass diagram. We find that most old pseudo-bulges are hosted by passive galaxies while majority of young bulges are hosted by galaxies that are star forming. Dividing our sample of S0 galaxies into early-type S0s and S0/a galaxies, we find that old pseudo-bulges are mainly hosted by early-type S0 galaxies while most of the pseudo-bulges in S0/a galaxies are young. We speculate that morphology plays a strong role in quenching of star formation in the disc of these S0 galaxies, which stops the growth of pseudo-bulges, giving rise to old pseudo-bulges and the observed age bimodality.
Localized orbital scaling correction for systematic elimination of delocalization error in density functional approximations
Authors: Li Chen , Zheng Xiao , Su Neil Qiang , Yang Weitao 
Published: September 2017

AbstractThe delocalization error of popular density functional approximations (DFAs) leads to diversified problems in present-day density functional theory calculations. For achieving a universal elimination of delocalization error, we develop a localized orbital scaling correction (LOSC) framework, which unifies our previously proposed global and local scaling approaches. The LOSC framework accurately characterizes the distributions of global and local fractional electrons, and is thus capable of correcting system energy, energy derivative and electron density in a self-consistent and size-consistent manner. The LOSC–DFAs lead to systematically improved results, including the dissociation of cationic species, the band gaps of molecules and polymer chains, the energy and density changes upon electron addition and removal, and photoemission spectra.