bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Organocatalytic Enantioselective Michael—Michael—Henry Reaction Cascade. An Entry to Highly Functionalized Hajos—Parrish‐Type Ketones with Five to Six Contiguous Stereogenic Centers and Two Quaternary Carbons.
Authors: Raja Arun , Hong Bor‐Cherng , Liao Ju‐Hsiou , Lee Gene‐Hsiang 
Published: July 2016

AbstractThe multicomponent reaction of 2‐methylcyclopentane‐1,3‐dione, nitroalkene, and α,β‐unsaturated aldehydes with the diphenylprolinol catalyst gives highly functionalized Hajos—Parrish‐type ketones with five to six contiguous stereocenters and two quaternary carbon stereogenic centers with high diastereoselectivity and enantioselectivity.
ChemInform Abstract: H‐Type Zeolite‐Catalyzed 1,4‐Addition of Benzene Derivatives to Labile Acrolein.
Authors: Hayashi Daijiro , Narisawa Tomoyuki , Masui Yoichi , Onaka Makoto 
Published: July 2016

AbstractA survey of acid catalysts for the 1,4‐addition of methoxy‐substituted benzenes to acrolein reveals that H‐Beta and H‐Y are the most suitable catalysts for the 1,4‐addition of benzene derivatives to acrolein to synthesize 3‐arylpropanals.
ChemInform Abstract: The Divergent Synthesis of Nitrogen Heterocycles by Rhodium(I)‐Catalyzed Intermolecular Cycloadditions of Vinyl Aziridines and Alkynes.
Authors: Feng Jian‐Jun , Lin Tao‐Yan , Zhu Chao‐Ze , Wang Huamin , Wu Hai‐Hong , Zhang Junliang 
Published: July 2016

AbstractUsing [Rh(nbd)2]BF4 as catalyst, a [3+2] cycloaddition takes place with broad substrate scope and high stereoselectivity.
ChemInform Abstract: An Efficient Biomimetic Aerobic Oxidation of Alcohols Catalyzed by Iron Combined with Amino Acids.
Authors: Zhang Guofu , Li Shasha , Lei Jie , Zhang Guihua , Xie Xiaoqiang , Ding Chengrong , Liu Renhua 
Published: July 2016

AbstractThe catalytic system FeCl3/L‐valine/TEMPO is used to convert primary and secondary alcohols into aldehydes and ketones in excellent yields under atmospheric oxygen.
ChemInform Abstract: Copper‐Catalyzed Regioselective C—H Iodination of Aromatic Carboxamides.
Authors: Wu Chuanguang , Zhou Hui , Wu Qiaolin , He Mina , Li Pei , Su Qing , Mu Ying 
Published: July 2016

AbstractN‐(Quinolin‐8‐yl)benzamides are regioselectively iodinated at the C‐5 position of the quinoline moiety using I2 as iodine source and PhI(OAc)2 as the oxidant.
ChemInform Abstract: Copper/Silver Cocatalyzed Oxidative Coupling of Vinylarenes with ICH2CF3 or ICH2CHF2 Leading to β‐CF3/CHF2‐Substituted Ketones.
Authors: Yi Niannian , Zhang Hao , Xu Chonghui , Deng Wei , Wang Ruijia , Peng Dongming , Zeng Zebing , Xiang Jiannan 
Published: July 2016

AbstractA simple and efficient approach towards ω‐fluorinated alkyl aryl ketones is developed.
ChemInform Abstract: Metal‐Free Oxidation of Primary Amines to Nitriles Through Coupled Catalytic Cycles.
Authors: Lambert Kyle M. , Bobbitt James M. , Eldirany Sherif A. , Kissane Liam E. , Sheridan Rose K. , Stempel Zachary D. , Sternberg Francis H. , Bailey William F. 
Published: July 2016

AbstractSynergism among intertwined catalytic cycles allows for selective oxidation of primary amines to nitriles in high yield.
ChemInform Abstract: An Aluminum Dihydride Working as a Catalyst in Hydroboration and Dehydrocoupling.
Authors: Yang Zhi , Zhong Mingdong , Ma Xiaoli , Nijesh Karikkeeriyil , De Susmita , Parameswaran Pattiyil , Roesky Herbert W. 
Published: July 2016

AbstractAn aluminum dihydride complex catalyzes both the hydroboration of terminal alkynes and the dehydrocoupling of boranes with amines, thiols, and phenols, respectively, to form compounds with B—N, B—S, and B—O under elimination of H2.
ChemInform Abstract: Regio‐ and Stereoselective Cyanotriflation of Alkynes Using Aryl(cyano)iodonium Triflates.
Authors: Wang Xi , Studer Armido 
Published: July 2016

AbstractThis protocol for direct vicinal alkyne cyanotriflation is characterized by complete regioselectivity, excellent stereoselectivity, and a broad scope of functional groups.
ChemInform Abstract: Intermolecular Hydroalkoxylation of N‐Allenyl Sulfonamides with Oximes Catalyzed by Cationic Gold(I) Salts
Authors: Ma Ting , Li Honghe , Sun Chenyang , Li Xiaoxiao , Zhao Zhigang 
Published: July 2016

Abstractstereoselectively affording a wide range of allyloximino E‐enesulfonamides
ChemInform Abstract: Rhodium Thiavinyl Carbenes from 1,2,3‐Thiadiazoles Enable Modular Synthesis of Multisubstituted Thiophenes.
Authors: Kurandina Daria , Gevorgyan Vladimir 
Published: July 2016

Abstract1,2,3‐Thiadiazoles are introduced as efficient precursors of hitherto unknown Rh thiavinyl carbene species.
ChemInform Abstract: Triflic Acid Catalyzed Intermolecular α‐Amination of Pterolactams to Give 5‐Arylaminopyrrolidinones via N‐Acyliminium Species.
Authors: Dumitriu Gina‐Mirabela , Bicu Elena , Eryuruk Ulku , Belei Dalila , Rigo Benoit , Daich Adam , Ghinet Alina 
Published: July 2016

AbstractCompounds (IIId), (IIIe), (IIIf), (VIII), and (XII) show inhibitory activity against human farnesyltransferase.
ChemInform Abstract: Metal‐Free Tandem Oxidative Coupling of Primary Alcohols with Azoles for the Synthesis of Hemiaminal Ethers.
Authors: Sun Jinwei , Zhang Yu , Mathan Sankaran , Wang Yi , Pan Yi 
Published: July 2016

AbstractThe protocol is successfully applied to various benzotriazole, tetrazole, carbazole, and indazole derivatives, but fails upon the transformation of indole or benzodiazole derivatives.
ChemInform Abstract: Synthesis of 2‐Alkenylquinoline by Reductive Olefination of Quinoline N‐Oxide under Metal‐Free Conditions.
Authors: Xia Hong , Liu Yuanhong , Zhao Peng , Gou Shaohua , Wang Jun 
Published: July 2016

AbstractThe reaction is proposed to proceed via a 1,3‐dipolar cycloaddition/acid‐assisted ring‐opening/dehydration sequence.
ChemInform Abstract: A Novel Synthesis of Disubstituted Quinazoline Diones with Differential N‐Substitution via a Copper‐Catalyzed Cross‐Coupling of Acyl Ureas.
Authors: Durham Emma , Perkins Dave , Scott James S. , Wang Jimmy , Watson Sam 
Published: July 2016

AbstractAn intramolecular Buchwald—Hartwig‐type cross‐coupling furnishes the title compounds in good yields using CuI/hydroxyproline as catalyst/ligand system.
ChemInform Abstract: Unprecedented Oxycyanation of Methylenecyclopropanes for the Facile Synthesis of Benzoxazine Compounds Containing a Cyano Group.
Authors: Yuan Yu‐Chao , Yang Hai‐Bin , Tang Xiang‐Ying , Wei Yin , Shi Min 
Published: July 2016

AbstractPalladium/boron cooperative catalysis enables both the N—CN bond cleavage and the subsequent tautomerization of the amide group allowing for selective oxycyanation of the cyclopropylidene double bond.
ChemInform Abstract: New ent‐Pimarane Diterpenes from the Roots of Aralia dumetorum.
Authors: Yang Chun‐Tao , Hou Shu‐Qun , Tian Kai , Hu Qiu‐Fen , Huang Xiang‐Zhong , Jiang Zhi‐Yong 
Published: July 2016

AbstractFour new ent‐pimarane diterpenes (I)‐(IV) are isolated from the roots of Aralia dumetorum together with three known compounds.
ChemInform Abstract: Eco‐Friendly Synthesis of 3‐Etherified Estrones.
Authors: Zheng Dong‐Qing , Jing Yu , Zheng Bing‐Ying , Ye Yun‐Fei , Xu Sheng , Tian Wei‐Sheng , Ma Hai‐Yan , Ding Kai 
Published: July 2016

AbstractEstrone ethers are prepared from easily available dienone (I) via an eco‐friendly tandem etherification/aromatization process.
ChemInform Abstract: Two New Cyclic Tetrapeptides of Streptomyces rutgersensis T009 Isolated from Elaphodus davidianus Excrement.
Authors: Li Shu‐Quan , Yang Ya‐Bin , Yang Xue‐Qiong , Jiang Yi , Li Zhen‐Jie , Li Xiao‐Zhan , Chen Xiu , Li Qi‐Lin , Qin Shao‐Huan , Ding Zhong‐Tao 
Published: July 2016

AbstractTwo new cyclic tetrapeptides (I) and (II) are isolated from the fermentation broth of Streptomyces rutgersensis T009 obtained from Elaphodus davidianus excrement together with 15 known compounds.
ChemInform Abstract: Seco‐Tremulanes from Cultures of the Basidiomycete Flavodon flavus BCC 17421.
Authors: Isaka Masahiko , Palasarn Somporn , Supothina Sumalee , Srichomthong Kitlada , Choeyklin Rattaket 
Published: July 2016

AbstractA new seco‐tremulane (I) is isolated from cultures of the basidiomycete Flavodon flavus BCC 17421 together with six known compounds.
ChemInform Abstract: Curly Arrows Meet Electron Density Transfers in Chemical Reaction Mechanisms: From Electron Localization Function (ELF) Analysis to Valence‐Shell Electron‐Pair Repulsion (VSEPR) Inspired Interpretation
Authors: Andres Juan , Berski Slawomir , Silvi Bernard 
Published: July 2016

AbstractReview: 173 refs.
Estimation of concentration‐dependent diffusion coefficients of gases in heavy oils/bitumen using experimental pressure‐decay data
Authors: Roman Francisco J. Pacheco , Hejazi S. Hossein 
Published: July 2016

AbstractThe diffusion coefficient (D) of gases in heavy oils is an important mass transfer parameter to model and design gas injection processes for oil recovery. The pressure‐decay technique (PDT) is one of the widely used experimental methods available to infer this coefficient. PDT records the declining gas phase pressure resulting from the diffusion of gas into heavy oil inside a pressure/volume/temperature (PVT) cell. Commonly, the gas phase pressure decay is modelled by use of Fick's second law along with gas‐phase mass balance equations and assuming a constant diffusion coefficient. In this work, we evaluate two concentration‐dependent diffusion coefficient functions, power‐law and exponential. A simple history matching technique is used to estimate the apparent diffusion coefficient (Do) and concentration dependency factor (ma) from pressure‐decay data. Extensive application of our method to experimental pressure‐decay tests shows that in addition to constant diffusion coefficients, both power‐law and exponential functions are capable of predicting the experimental data. This implies that other experimental techniques are required to extract the functionality of diffusion coefficients with gas concentrations in heavy oil.
A New Way to Produce Cellobiose Carbonates Using Green Chemistry
Authors: Khiari R. , Brochier‐Salon M.‐C. , Mhenni M. F. , Mauret E. , Belgacem M. N. 
Published: July 2016

AbstractThe preparation of cellulose derivatives using green (i.e., environmentally friendly) reagents would improve sustainability and reduce concerns arising from the use of non‐green reagents. The objective of this work was to prepare cellobiose carbonate using a green reagent, dimethyl carbonate. The carbonation reaction was carried out in the presence of ethanolic potassium hydroxide solution and dimethyl carbonate for 6 h at a range of temperatures (25–70 °C). A cellobiose derivative was successfully prepared with a recovered yield of more than 70 % and characterized by FTIR and NMR spectroscopy techniques. The presence of a grafted disaccharide with a degree of substitution higher than 2 was determined by 13C NMR analysis. The spectra of the prepared cellobiose carbonate exhibited peaks that were associated with cellulose molecules (C1–C6) and corresponded to carbonate functions at around 159.4 ppm.
Conservation implications of a lack of relationship between baseline glucocorticoids and fitness in a wild passerine
Authors: Madliger Christine L. , Love Oliver P. 
Published: July 2016

AbstractThe application of physiological measures to conservation monitoring has been gaining momentum and, while a suite of physiological traits are available to ascertain disturbance and condition in wildlife populations, glucocorticoids (i.e., GCs; cortisol and corticosterone) are the most heavily employed. The interpretation of GC levels as sensitive indicators of population change necessitates that GCs and metrics of population persistence are linked. However, the relationship between GCs and fitness may be highly context‐dependent, changing direction, or significance, depending on the GC measure, fitness metric, life history stage, or other intrinsic and extrinsic contexts considered. We examined the relationship between baseline plasma corticosterone (CORT) levels measured at two periods of the breeding season and three metrics of fitness (offspring quality, reproductive output, and adult survival) in female Tree Swallows (Tachycineta bicolor). Specifically, we investigated whether (1) a relationship between baseline CORT metrics and fitness exists in our population, (2) whether the inclusion of energetic contexts, such as food availability, reproductive investment, or body mass, could alter or improve the strength of the relationship between CORT and fitness, and (3) whether energetic contexts could better predict fitness compared to CORT metrics. Importantly, we investigated these relationships in both natural conditions and under an experimental manipulation of foraging profitability (feather clipping) to determine the influence of an environmental constraint on GC–fitness relationships. We found a lack of relationship between baseline CORT and both short‐ and long‐term metrics of fitness in control and clipped birds. In contrast, loss in body mass over reproduction positively predicted reproductive output (number of chicks leaving the nest) in control birds; however, the relationship was characterized by a low R2 (5%), limiting the predictive capacity, and therefore the application potential, of such a measure in a conservation setting. Our results stress the importance of ground‐truthing GC–fitness relationships and indicate that baseline GCs will likely not be easily employed as conservation biomarkers across some species and life history stages. Given the accumulating evidence of temporally dynamic, inconsistent, and context‐dependent GC–fitness relationships, placing effort towards directly measuring fitness traits, rather than plasma GC levels, will likely be more worthwhile for many conservation endeavours.
Movement reveals scale dependence in habitat selection of a large ungulate
Authors: Northrup Joseph M. , Anderson Charles R. , Hooten Mevin B. , Wittemyer George 
Published: July 2016

AbstractEcological processes operate across temporal and spatial scales. Anthropogenic disturbances impact these processes, but examinations of scale dependence in impacts are infrequent. Such examinations can provide important insight to wildlife–human interactions and guide management efforts to reduce impacts. We assessed spatiotemporal scale dependence in habitat selection of mule deer (Odocoileus hemionus) in the Piceance Basin of Colorado, USA, an area of ongoing natural gas development. We employed a newly developed animal movement method to assess habitat selection across scales defined using animal‐centric spatiotemporal definitions ranging from the local (defined from five hour movements) to the broad (defined from weekly movements). We extended our analysis to examine variation in scale dependence between night and day and assess functional responses in habitat selection patterns relative to the density of anthropogenic features. Mule deer displayed scale invariance in the direction of their response to energy development features, avoiding well pads and the areas closest to roads at all scales, though with increasing strength of avoidance at coarser scales. Deer displayed scale‐dependent responses to most other habitat features, including land cover type and habitat edges. Selection differed between night and day at the finest scales, but homogenized as scale increased. Deer displayed functional responses to development, with deer inhabiting the least developed ranges more strongly avoiding development relative to those with more development in their ranges. Energy development was a primary driver of habitat selection patterns in mule deer, structuring their behaviors across all scales examined. Stronger avoidance at coarser scales suggests that deer behaviorally mediated their interaction with development, but only to a degree. At higher development densities than seen in this area, such mediation may not be possible and thus maintenance of sufficient habitat with lower development densities will be a critical best management practice as development expands globally.
What explains patterns of species richness? The relative importance of climatic‐niche evolution, morphological evolution, and ecological limits in salamanders
Authors: Kozak Kenneth H. , Wiens John J. 
Published: July 2016

AbstractA major goal of evolutionary biology and ecology is to understand why species richness varies among clades. Previous studies have suggested that variation in richness among clades might be related to variation in rates of morphological evolution among clades (e.g., body size and shape). Other studies have suggested that richness patterns might be related to variation in rates of climatic‐niche evolution. However, few studies, if any, have tested the relative importance of these variables in explaining patterns of richness among clades. Here, we test their relative importance among major clades of Plethodontidae, the most species‐rich family of salamanders. Earlier studies have suggested that climatic‐niche evolution explains patterns of diversification among plethodontid clades, whereas rates of morphological evolution do not. A subsequent study stated that rates of morphological evolution instead explained patterns of species richness among plethodontid clades (along with “ecological limits” on richness of clades, leading to saturation of clades with species, given limited resources). However, they did not consider climatic‐niche evolution. Using phylogenetic multiple regression, we show that rates of climatic‐niche evolution explain most variation in richness among plethodontid clades, whereas rates of morphological evolution do not. We find little evidence that ecological limits explain patterns of richness among plethodontid clades. We also test whether rates of morphological and climatic‐niche evolution are correlated, and find that they are not. Overall, our results help explain richness patterns in a major amphibian group and provide possibly the first test of the relative importance of climatic niches and morphological evolution in explaining diversity patterns.
Glucose solution is more effective in relieving pain in neonates than non‐nutritive sucking: A randomized clinical trial
Authors: Lima A.G.C.F. , Santos V.S. , Nunes M.S. , Barreto J.A.A , Ribeiro C.J.N. , Carvalho J. , Ribeiro M.C.O. 
Published: July 2016

AbstractBackgroundFew studies have compared the analgesic effect of 25% glucose and non‐nutritive sucking. We compared the analgesic effect of 25% glucose and non‐nutritive sucking in newborns undergoing hepatitis B vaccination. Our hypothesis is that 25% glucose is more effective in relieving pain than non‐nutritive sucking.MethodsA randomized clinical trial with 78 healthy newborns was performed. Neonates were assigned randomly to receive 25% glucose (G25) and non‐nutritive sucking (NNS). Pain was assessed using the Neonatal Infant Pain Scale (NIPS) before and during the immunization procedure. In addition, we evaluated various physiological parameters and crying time.ResultsNeonates who received 25% glucose registered lower NIPS scores than those from the NNS group [mean (SD), 3.3 (2.1) vs. 5.6 (1.6), p < 0.001]. The crying time was shorter among newborns in the G25 group than in the NNS and control groups.ConclusionThe use of 25% glucose before the vaccination procedure was more effective in relieving acute pain, with newborns in the G25 group registering scores two times lower on the NIPS scale. The clinical practice of administering 25% glucose is therefore a suggested nondrug measure for pain relief during painful procedures.SignificanceNeonates who received 25% glucose registered lower NIPS scores than those from the NNS group; the crying time was shorter among newborns in the G25 group than in the NNS and control groups; the use of 25% glucose before the vaccination procedure was more effective in relieving acute pain.
Chronic postsurgical pain in patients 5 years after cardiac surgery: A prospective cohort study
Authors: Gjeilo K.H. , Stenseth R. , Wahba A. , Lydersen S. , Klepstad P. 
Published: July 2016

AbstractBackgroundChronic postsurgical pain (CPSP) is a common complication after many surgical procedures, including cardiac surgery. The prevalence of CPSP after cardiac surgery ranges from 9.5% to 56%. Most studies on CPSP after cardiac surgery are retrospective and long‐term prospective studies are scarce. The aim of this study was to follow CPSP and health‐related quality of life (HRQOL) prospectively in a cohort of patients, emphasizing the prevalence from 12 months to 5 years.MethodsA total of 534 patients (23% ≥75 years, 67% men) were consecutively included before surgery. Study‐specific questionnaires and the Brief Pain Inventory (BPI) were used to measure CPSP at baseline, 12 months and 5‐year follow‐up. Short‐Form Health Survey (SF‐36) was used to measure HRQOL.ResultsAmong 458 patients who were alive after 5 years, 82% responded (n = 373). The majority, 89.8% (335/373), did not report CPSP, neither 12 months nor 5 years after surgery. Among the 38 patients who reported CPSP after 12 months, 24 (63%) patients did not report CPSP after 5 years. The overall prevalence of CPSP after 5 years was 3.8% (14/373). Patients reporting CPSP and resolved CPSP had lower scores on HRQOL and more pain preoperatively than patients who did not report CPSP.ConclusionsThe prevalence of CPSP was lower in this study than previously reported. Among the patients reporting CPSP at 12 months, 63% did not report CPSP after 5 years. Hence, the observed decline in CPSP is in line with studies evaluating CPSP in noncardiac surgery.SignificanceThe prevalence of chronic postsurgical pain (CPSP) at 5 years after surgery of 3.8% is lower than previously reported. The majority of patients reporting CPSP after 12 months did not report CPSP after 5 years.
Child attention to pain and pain tolerance are dependent upon anxiety and attention control: An eye‐tracking study
Authors: Heathcote L.C. , Lau J.Y.F. , Mueller S.C. , Eccleston C. , Fox E. , Bosmans M. , Vervoort T. 
Published: July 2016

AbstractBackgroundPain is common and can be debilitating in childhood. Theoretical models propose that attention to pain plays a key role in pain outcomes, however, very little research has investigated this in youth. This study examined how anxiety‐related variables and attention control interacted to predict children's attention to pain cues using eye‐tracking methodology, and their pain tolerance on the cold pressor test (CPT).MethodsChildren aged 8–17 years had their eye‐gaze tracked whilst they viewed photographs of other children displaying painful facial expressions during the CPT, before completing the CPT themselves. Children also completed self‐report measures of anxiety and attention control.ResultsFindings indicated that anxiety and attention control did not impact children's initial fixations on pain or neutral faces, but did impact how long they dwelled on pain versus neutral faces. For children reporting low levels of attention control, higher anxiety was associated with less dwell time on pain faces as opposed to neutral faces, and the opposite pattern was observed for children with high attention control. Anxiety and attention control also interacted to predict pain outcomes. For children with low attention control, increasing anxiety was associated with anticipating more pain and tolerating pain for less time.ConclusionsThis is the first study to examine children's attention to pain cues using eye‐tracking technology in the context of a salient painful experience. Data suggest that attention control is an important moderator of anxiety on multiple outcomes relevant to young people's pain experiences.SignificanceThis study uses eye tracking to study attention to pain cues in children. Attention control is an important moderator of anxiety on attention bias to pain and tolerance of cold pressor pain in youth.