bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epicardial Fat Thickness in Non-Obese Neurologically Impaired Children: Association with Unfavorable Cardiometabolic Risk Profile
Authors: Calcaterra Valeria , Cena Hellas , Casali Pietro Mariano , Iacobellis Gianluca , Albertini Riccardo , De Amici Mara , de Silvestri Annalisa , Comparato Calogero , Pelizzo Gloria 
Published: January 2018

<b><i>Background:</i></b> Cardiovascular risk is reported in disabled children and epicardial fat (EF) is considered an independent predictor of cardiovascular disease (CVD). No data on the EF thickness (EFT) evaluation in disabled children have been published. <b><i>Objective:</i></b> We investigated EFT in neurologically impaired (NI) children; its relationship with their metabolic profile was also considered. <b><i>Methods:</i></b> Clinical data, body composition estimation, biochemical profile, and ultrasound-measured EFT were performed in 32 disabled patients (12.4 ± 6.3 years). Pathological parameters were defined using the following criteria: waist circumference &#x3e;95th<sup></sup> percentile, waist to height ratio (WHtR) &#x3e;0.5, total cholesterol and triglycerides (TG) values &#x3e;95th percentile, high density lipoprotein cholesterol &#x3c;5th percentile, fasting blood glucose &#x3e;100 mg/dL, homeostasis model assessment for insulin resistance (HOMA) &#x3e;97.5th<sup></sup> percentile, and EFT &#x3e;3.6 mm. <b><i>Results:</i></b> EFT values in NI children were higher compared with control group values (<i>p</i> = 0.02). EFT correlated with gender (<i>p</i> &#x3c; 0.001), age (<i>p</i> = 0.02), pubertal stage (<i>p</i> = 0.04), as well as WHtR (<i>p</i> = 0.03). A correlation between EFT and leptin was also noted (<i>p</i> = 0.04). EFT levels significantly correlated with pathological TG (<i>p</i> = 0.01) and HOMA-IR (<i>p</i> = 0.04). <b><i>Conclusions:</i></b> Higher EFT was observed in NI children compared with controls. EFT values correlated with clinical, metabolic, and endocrinological parameters. Ultrasound-measured EFT<i></i> could be used to promptly detect subclinical CVD and to prevent adverse outcomes in disabled children.
КОМПЕТЕНТНІСНО-ІНТЕГРАТИВНИЙ ПІДХІД У ПРОФЕСІЙНІЙ ПІДГОТОВЦІ МАЙБУТНІХ ПРОВІЗОРІВ
Authors: Toziuk O. Yu. 
Published: January 2018

Мета роботи – охарактеризувати сучасні методи викладання дисциплін циклу професійної підготовки студентам фармацевтичного факультету та розкрити особливості їх впровадження у навчальний процес.Основна частина. У статті наведено аналіз даних наукової та методичної літератури і власний досвід використання компетентнісного та інтегративного підходів у навчальному процесі на кафедрі фармації Вінницького національного медичного університету імені М. І. Пирогова. Використання міждисциплінарної інтеграції в освітній діяльності передбачає побудову логічних узагальнень при послідовному вивченні програмних дисциплін. Таким чином, інтегративний підхід є важливим елементом закріплення умінь і навичок студентів. Наведено шляхи формування найбільш важливих професійних компетентностей майбутніх провізорів: пізнавальної, аналітичної та комунікативної. Представлено види роботи та можливі методичні підходи, використання яких під час навчального процесу дозволяє підготувати висококваліфікованого фахівця. Важливим елементом є робота з ситуаційними задачами та моделювання елементів професійної діяльності. При цьому велике значення приділяється практичній підготовці студентів, що полягає у виготовленні лікарських форм за прописами, веденні документації фінансово-господарської діяльності, складанні матеріальних балансів та технологічних схем.Формуванню фахових компетентностей сприяє також індивідуальна самостійна робота студентів. Виконання наукових робіт під наглядом наукового керівника поглиблює знання з дисципліни, інтенсифікує творчий та дослідницький потенціал.Висновок. Використання інноваційних освітніх методик у навчальному процесі підвищує якісний рівень знань студентів і зацікавленість в обраній професії.
ДОСВІД ЗАСТОСУВАННЯ ТЕЛЕМЕДИЧНИХ ТЕХНОЛОГІЙ НА ПЕРВИННОМУ РІВНІ МЕДИЧНОЇ ДОПОМОГИ
Authors: Korda M. M. , Shulhai A. G. , Zaporozhan S. Y. , Klisch I. M. 
Published: January 2018

Мета роботи – висвітлити досвід використання телемедичних технологій у навчально-практичних центрах первинної медико-­санітарної допомоги Тернопільського державного медичного університету імені І. Я. Горбачевського.Основна частина. У статті висвітлено приклади застосування телемедичних технологій у навчально-практичних центрах первинної медико-санітарної допомоги Тернопільського державного медичного університету імені І. Я. Горбачевського. Подано перелік телемедичних послуг, які доцільно впровадити на первинному рівні медичної допомоги.Висновок. Створені Тернопільським державним медичним університетом імені І. Я. Горбачевського навчально-практичні центри засвідчують реальні можливості виконання Закону України “Про підвищення доступності та якості медичного обслуговування у сільській місцевості” шляхом запровадження на рівні закладів первинної медичної допомоги технологій телемедицини.
Agô!
Authors: Grillo Angela Teodoro , Araújo Giovanna Gobbi Alves , Araujo Manuella Miki Souza 
Published: January 2018

A décima edição da Opiniães: revista dos alunos de literatura brasileira convida o leitor a refletir sobre as relações estéticas, sociais e políticas que envolvem a literatura negra e/ou afro-brasileira. Os sete artigos acadêmicos que compõem o dossiê temático – assinados por Luciana Marquesini Mongim, Luciana Alves Santos, Fernanda Rodrigues Miranda, Fabiana Carneiro da Silva, Luciana Martins Diogo e Ana Paula Simioni, Francys Lindoso Cavalcanti e Fabiane Cristine Rodrigues – abordam, de maneira plural e instigante, aspectos variados da presença negra na literatura brasileira. Além dos artigos científicos, este número conta com uma coletânea que reúne poemas, contos, crônicas e dramaturgia de escritoras e escritores negros contemporâneos - Allan da Rosa, Cidinha da Silva, Cuti, Fábio Mandingo, Jeferson Tenório, Lia Vieira e Le Tícia Conde, Akins Kintê, Cristiane Sobral, Dinha, Elizandra Souza, Le Tícia Conde, Lívia Natália, luz ribeiro e Tula Pilar Ferreira; uma seção de entrevistas com as importantes participações de Esmeralda Ribeiro, Eduardo de Assis Ribeiro, Cuti e Elena Pajaro Peres; uma seção de resenhas com os trabalhos de Larissa Souza e Lígia Balista; e, por fim, uma seção de tradução poética, com a apresentação de três poemas de Langston Hughes traduzidos para o português por Giovanna Gobbi Alves Araújo. O tema da presença negra na literatura brasileira conjuga de forma privilegiada diferentes performatividades, vozes científicas-femininas-periféricas-plásticas-poéticas-musicais nascidas de um universo vasto, desafiador, movediço –, território cultural, social e simbólico, diante do qual dizemos: “Agô!”
Autor, editor e editado: Erico Verissimo sob o crivo norte-americano
Authors: Minchillo Carlos Cortez 
Published: January 2018

Este artigo trata de alguns aspectos do complexo trânsito intercultural de livros e da política de tradução. Baseado em pesquisa de arquivo e focalizando a carreira internacional de Erico Verissimo, este trabalho sintetiza o processo de publicação nos Estados Unidos das obras de Verissimo e revela várias reações que elas provocaram em editores, tradutores e pareceristas. Proponho que a trajetória das edições norte-americanas de Erico Verissimo ilumina procedimentos de publicação, expectativas editoriais e filtros culturais que impactam a análise de literatura estrangeira e a seleção de títulos para tradução.
Macrophage Transitions in Heart Valve Development and Myxomatous Valve Disease
Authors: Hulin Alexia , Anstine Lindsey J. , Kim Andrew J. , Potter Sarah J. , DeFalco Tony , Lincoln Joy , Yutzey Katherine E. 
Published: January 2018

Objective—
Hematopoietic-derived cells have been reported in heart valves but remain poorly characterized. Interestingly, recent studies reveal infiltration of leukocytes and increased macrophages in human myxomatous mitral valves. Nevertheless, timing and contribution of macrophages in normal valves and myxomatous valve disease are still unknown. The objective is to characterize leukocytes during postnatal heart valve maturation and identify macrophage subsets in myxomatous valve disease.

Approach and Results—

Leukocytes are detected in heart valves after birth, and their numbers increase during postnatal valve development. Flow cytometry and immunostaining analysis indicate that almost all valve leukocytes are myeloid cells, consisting of at least 2 differentially localized macrophage subsets and dendritic cells. Beginning a week after birth, increased numbers of CCR2+ (C-C chemokine receptor type 2) macrophages are present, consistent with infiltrating populations of monocytes, and macrophages are localized in regions of biomechanical stress in the valve leaflets. Valve leukocytes maintain expression of CD (cluster of differentiation) 45 and do not contribute to significant numbers of endothelial or interstitial cells. Macrophage lineages were examined in aortic and mitral valves of
Axin2
KO (knockout) mice that exhibit myxomatous features. Infiltrating CCR2+ monocytes and expansion of CD206-expressing macrophages are localized in regions where modified heavy chain hyaluronan is observed in myxomatous valve leaflets. Similar colocalization of modified hyaluronan and increased numbers of macrophages were observed in human myxomatous valve disease.

Conclusions—
Our study demonstrates the heterogeneity of myeloid cells in heart valves and highlights an alteration of macrophage subpopulations, notably an increased presence of infiltrating CCR2+ monocytes and CD206+ macrophages, in myxomatous valve disease.
Entrepreneurship Education and Research outside North America
Authors: Brockhaus Robert H. 
Published: January 2018

Many developing countries have been forced by growing budget deficits and mounting foreign debt burdens to find ways to reduce the size of the public sector or at least to arrest further growth. Thus the public sector can no longer be expected to provide employment for a large portion of new graduates as has traditionally been the case. Privatization of inefficient and over-staffed public enterprises is often one element of many countries’ efforts to reduce public spending, and in the process substantial retrenchment must occur. This adds to the unemployment problem, at least in the short and medium term. In their efforts to restructure and reduce the public sector, many governments are turning to the private sector to generate increasing employment and to provide many of the services previously provided by government. The private sector is recognized as the main engine of growth. The capacity of modern, large-scale industry to employ the growing number of labor force entrants is restricted, however, because of limited size and capital-intensive production methods. Thus, the private small enterprise sector is seen both as having the greatest potential for creating substantial employment at lower levels of investment and as providing a seedbed for enterpreneurial talent and a testing place for new industries. The U.S. and Europe are not the only places in the world where entrepreneurship is recognized as playing a major role in economic development. Even former communist countries are focusing a great amount of effort on fostering entrepreneurship. Following the government initiatives, universities are not only offering courses, but are also conducting a growing amount of both practical and theoretical research on entrepreneurship issues. As entrepreneurs and small business research conferences become even more “international” in attendance and issues, there will be fewer differences between different regions of the world from an academic perspective.
Contributing Editor's Feature
Authors: Birley Sue 
Published: January 2018

There is an increasing, but as yet small, body of literature which questions the validity of assuming universal truths in the field of entrepreneurship. Cross cultural studies are beginning to highlight national differences in the motivations of entrepreneurs and to identify the extent to which these are due to the very different environments in which they operate. Despite this, there continues to be an assumption that, whilst the people and the context may vary, the models of economic regeneration are universal. Nowhere is this dichotomy clearer than in the “third world.” In the spirit of bringing this debate into the “mainstream literature,” I asked Malcolm Harper to write a piece on his view of Enterprise Development in Poorer Nations. Although based at Cranfield, Malcolm has spent the last 20 years working in developing countries helping to develop and implement new enterprise strategies. In his work he considers his general focus “[expost rationalised] is empowerment for disadvantaged through enterprise.” I hope that you find his views illuminating. If you do you can explore the issues further in a new journal he has recently launched, “Small Enterprise Development,” which concentrates upon this field.
A Bayesian two-stage regression approach of analysing longitudinal outcomes with endogeneity and incompleteness
Authors: Bhuyan Prajamitra , Biswas Jayabrata , Ghosh Pulak , Das Kiranmoy 
Published: January 2018

Abstract: Two-stage regression methods are typically used for handling endogeneity in the simultaneous equations models in economics and other social sciences. However, the problem is challenging in the presence of incomplete response and/or incomplete endogenous covariate(s). We propose a Bayesian approach for the joint modelling of incomplete longitudinal continuous response and an incomplete count endogenous covariate, where the incompleteness is caused by the censorship through a selection mechanism. We define latent continuous variables which are left-censored at zero and develop a Gibbs sampling algorithm for the simultaneous estimation of the model parameters. We consider partially varying coefficients regression models containing covariates with fixed and time-varying effects on the response. Our work is motivated by a sample dataset from the Health and Retirement Study (HRS) for modelling the out-of-pocket medical cost, where the number of hospital admissions is considered as an endogenous covariate. Our analysis addresses some of the previously unanswered questions on the physical and financial health of the older population based on HRS data. Simulation studies are performed for assessing the usefulness of the proposed method compared to its competitors.
Genomic CDKN2A/2B deletions in adult Ph+ ALL are adverse despite allogeneic stem cell transplantation
Authors: Pfeifer Heike , Raum Katharina , Markovic Sandra , Nowak Verena , Fey Stephanie , Obländer Julia , Pressler Jovita , Böhm Verena , Brüggemann Monika , Wunderle Lydia , Hüttmann Andreas , Wäsch Ralph , Beck Joachim , Stelljes Matthias , Viardot Andreas , Lang Fabian , Hoelzer Dieter , Hofmann Wolf-Karsten , Serve Hubert , Weiss Christel , Goekbuget Nicola , Ottmann Oliver G. , Nowak Daniel 
Published: January 2018

Key PointsGenomic deletions of CDKN2A/2B are a new independent prognostic risk factor in adult Ph+ ALL.
Consent to Treatment: Legal and Ethical Aspects
Authors: Bowden Paul 
Published: January 2018

In anticipating the consultative paper A Review of the Mental Health Act, 1959 the College's Public Policy Committee prepared a report in 1974 (News and Notes, October, November 1974). The second of six points covered in the report related to compulsory detention and treatment. It reads:The Working Party are firmly of the view that compulsory powers should include the power to treat patients compulsorily for any form of mental disorder, but has doubts as to how far certain types of treatment should be applied on the sole authority of the Responsible Medical Officer against the patient's will or when he is incapable of giving consent.
Prevalence and factors associated with burnout among frontline primary health care providers in low- and middle-income countries: A systematic review
Authors: Dugani Sagar , Afari Henrietta , Hirschhorn Lisa R. , Ratcliffe Hannah , Veillard Jeremy , Martin Gayle , Lagomarsino Gina , Basu Lopa , Bitton Asaf 
Published: January 2018

Background: Primary health care (PHC) systems require motivated and well-trained frontline providers, but are increasingly challenged by the growing global shortage of health care workers. Burnout, defined as emotional exhaustion, depersonalization, and low personal achievement, negatively impacts motivation and may further decrease productivity of already limited workforces. The objective of this review was to analyze the prevalence of and factors associated with provider burnout in low and middle-income countries (LMICs). Methods: We performed a systematic review of articles on outpatient provider burnout in LMICs published up to 2016 in three electronic databases (EMBASE, MEDLINE, and CAB). Articles were reviewed to identify prevalence of and risk factors associated with provider burnout. Results: A total of 6,182 articles were identified, with 20 meeting eligibility criteria. We found heterogeneity in definition and prevalence of burnout. Most studies assessed burnout using the Maslach Burnout Inventory. All three dimensions of burnout were seen across multiple cadres (physicians, nurses, community health workers, and pharmacists). Frontline nurses in South Africa had the highest prevalence of high emotional exhaustion and depersonalization, while PHC providers in Lebanon had the highest reported prevalence of low personal achievement. Higher provider burnout was associated with high job stress, high time pressure and workload, and lack of organizational support. Conclusions: Our comprehensive review of published literature showed that provider burnout is an important problem across various health care providers in LMICs. Further studies are required to better measure the prevalence, causes and consequences of burnout, and guide the development of effective interventions to reduce or prevent burnout.
Advertising Content and Consumer Engagement on Social Media: Evidence from Facebook
Authors: Lee Dokyun , Hosanagar Kartik , Nair Harikesh S. 
Published: January 2018

We describe the effect of social media advertising content on customer engagement using data from Facebook. We content-code 106,316 Facebook messages across 782 companies, using a combination of Amazon Mechanical Turk and natural language processing algorithms. We use this data set to study the association of various kinds of social media marketing content with user engagement—defined as Likes, comments, shares, and click-throughs—with the messages. We find that inclusion of widely used content related to brand personality—like humor and emotion—is associated with higher levels of consumer engagement (Likes, comments, shares) with a message. We find that directly informative content—like mentions of price and deals—is associated with lower levels of engagement when included in messages in isolation, but higher engagement levels when provided in combination with brand personality–related attributes. Also, certain directly informative content, such as deals and promotions, drive consumers’ path to conversion (click-throughs). These results persist after incorporating corrections for the nonrandom targeting of Facebook’s EdgeRank (News Feed) algorithm and so reflect more closely user reaction to content than Facebook’s behavioral targeting. Our results suggest that there are benefits to content engineering that combines informative characteristics that help in obtaining immediate leads (via improved click-throughs) with brand personality–related content that helps in maintaining future reach and branding on the social media site (via improved engagement). These results inform content design strategies. Separately, the methodology we apply to content-code text is useful for future studies utilizing unstructured data such as advertising content or product reviews. The online appendix is available at https://doi.org/10.1287/mnsc.2017.2902 . This paper was accepted by Chris Forman, information systems.
Framing Information and its Impact on Saving Decision in Conventional and Sharia Banks: Experimental Study of Students of the Faculty of Islamic Economics and Business in Yogyakarta
Authors: Widayanti Ipuk 
Published: January 2018

Islamic and Conventional Banks in delivering information of margin in saving product have different ways. Islamic bank uses “nisbah” while conventional bank uses interest. Both have different words and disclosure but in the nominal calculation of nisbah and interest is same, because Islamic bank uses Profit Equilization Reserve which the function is as allowance, and to simply it, Islamic banking informs that to consumer as Equivalent Rate. By using Attribute Framing and Risky Choice Framing this research aims to test the information frame of nisbah and interest and it influences on saving decision making. Quasi Experiment Model is used with 49 students of Islamic Economic Studies as subject of experimental group and 20 students of other studies except Islamic Economic as subject of control group. Experimental design of this research is between subject 2X2 by using 2 cases and Random Assignment technique. Two Way ANOVA is used as analitical tool. The result of this research is when information of margin is framed in gain domain/positive frame and loss domain/positive frame subject decision in saving is less risky while when information of margin is framed in gain domain/negative frame and loss domain/negative frame subject decision in saving is risk seeking. The largest framing effect is on the certain/probability (gain domain/positive frame) and the smallest effect is on uncertain/presentation (loss domain/negative frame).
Export-Led Growth Hypothesis: Comparison Between Islamic and Non-Islamic Countries in ASEAN
Authors: Syarif Ahmad 
Published: January 2018

This study aims to prove and analyze the effect of export growth on economic growth in the ASEAN countries. Using annual data from 2004 to 2014, the empirical result shows that export growth is significant and gives positive impact on the economic growth in ASEAN. However, investment and labor-force are less to affect the economic growth in ASEAN. This study also provides strong evidence that supports the hypothesis of export-led growth as described by Nurkse (Moon, 1997). Export-led growth is an economic strategy that is also used by Islamic countries in ASEAN. Export-led growth has two important reasons, it can generate profits and allow countries to balance their finances and the export growth can lead to greater productivity. This is consistent with the macro theory assumes that exports are injection to the economy (McCombie et al, 1994).
Smoothness of definite unitary eigenvarieties at critical points
Authors: Bergdall John 
Published: January 2018

Abstract
We compute an upper bound for the dimension of the tangent spaces at classical points of certain eigenvarieties associated with definite unitary groups, especially including the so-called critically refined cases. Our bound is given in terms of “critical types” and when our bound is minimized it matches the dimension of the eigenvariety. In those cases, which we explicitly determine, the eigenvariety is necessarily smooth and our proof also shows that the completed local ring on the eigenvariety is naturally a certain universal Galois deformation ring.
Perspectives and Problems of Harmonizing Energy Legislation of Ukraine with the European Union Standards
Authors: Volodymyrivna Komelina Olha , Adamivna Shcherbinina Svitlana 
Published: January 2018

Summary
Essence, features and components of the energy market was investigated in the article. Regulatory support of energy efficiency and energy saving in the European Union and Ukraine was analyzed. Ukraine obligations due to the harmonization of the energy legislation with the EU standards were defined. Problems in the housing and communal services (HCS) as one of the largest consumers of energy resources were revealed.