bluuebunny/crossref_metadata_2025_split huggingface dataset:
Displacement Efficiency for Low-Salinity Polymer Flooding Including Wettability Alteration
Authors: Khorsandi Saeid , Qiao Changhe , Johns Russell T. 
Published: October 2016

SummaryPolymer flooding can significantly improve sweep and delay breakthrough of injected water, thereby increasing oil recovery. Polymer viscosity degrades in reservoirs with high-salinity brines, so it is advantageous to inject low-salinity water as a preflush. Low-salinity waterflooding (LSW) can also improve local-displacement efficiency by changing the wettability of the reservoir rock from oil-wet to more water-wet. The mechanism for wettability alteration for LSW in sandstones is not very well-understood; however, experiments and field studies strongly support that cation-exchange (CE) reactions are the key elements in wettability alteration. The complex coupled effects of CE reactions, polymer properties, and multiphase flow and transport have not been explained to date.This paper presents the first analytical solutions for the coupled synergistic behavior of LSW and polymer flooding considering CE reactions, wettability alteration, adsorption, inaccessible pore volume (IPV), and salinity effects on polymer viscosity. A mechanistic approach that includes the CE of Ca2+, Mg2+, and Na+ is used to model the wettability alteration. The aqueous phase viscosity is a function of polymer and salt concentrations. Then, the coupled multiphase-flow and reactive-transport model is decoupled into three simpler subproblems—the first in which CE reactions are solved, the second in which a variable polymer concentration can be added to the reaction path, and the third in which fractional flows can be mapped onto the fixed cation and polymer-concentration paths. The solutions are used to develop a front-tracking algorithm, which can solve the slug-injection problem of low-salinity water as a preflush followed by polymer. The results are verified with experimental data and PennSim (2013), a general-purpose compositional simulator.The analytical solutions show that decoupling allows for estimation of key modeling parameters from experimental data, without considering the chemical reactions. Recovery can be significantly enhanced by a low-salinity preflush before polymer injection. For the cases studied, the improved oil recovery (IOR) for a chemically tuned low-salinity polymer (LSP) flood can be as much as 10% original oil in place (OOIP) greater than with considering polymer alone. The results show the structure of the solutions, and, in particular, the velocity of multiple shocks that develop. These shocks can interact, changing recovery. For example, poor recoveries obtained in corefloods for small-slug sizes of low salinity are explained by the intersection of shocks without considering mixing. The solutions can also be used to benchmark numerical solutions and for experimental design. We demonstrate the potential of LSP flooding as a less-expensive and more-effective way for performing polymer flooding when the reservoir wettability can be altered with chemically tuned low-salinity brine.
Nonlocal Diffusion in Fractured Rocks
Authors: Raghavan R.. , Chen C.. , DaCunha J. J. 
Published: October 2016

Summary
Space–time fractional diffusion in a linear, bounded region is considered. An analytical expression for the pressure distribution in the bounded region is derived in terms of the Mittag-Leffler function and the Laplace transformation. Comparisons with numerical solutions indicate excellent agreement. A convenient expression that incorporates a combination of Dirichlet and Neumann boundary conditions, particularly suitable for rapid computations, has been elusive until now. Responses that may be expected in nanoporous reservoirs that are usually produced through horizontal wells containing multiple hydraulic fractures are deduced. It is shown that the existence of obstacles, discontinuities, and other complex flow paths in fractured reservoirs express themselves in the form of power-law declines, whereas long-range interactions reflective of rapid communication, interestingly, express themselves as exponential declines. An understanding of the simultaneous influences of these two effects is the purpose of this study. The application to the “trilinear” model often used to evaluate well performance in shales is demonstrated.
Central anticholinergic syndrome following reversal of neuromuscular blockade in a neonate
Authors: Selvamani Breethaa Janani , Hussain Aftab , Rahman Faizur , Fatima Nida 
Published: October 2016

SummaryCentral anticholinergic syndrome (CAS) is rare in neonates. We report a case in a 10‐day‐old baby weighing 2.5 kg, following reversal of neuromuscular blockade using 0.1 mg atropine and 120 μg neostigmine. The use of atropine in 0.01‐0.02 mg.kg‐1 dose rather than the recommended minimum dose of 0.1 mg may have prevented this complication.
Job syndrome and an allergy to a component in medicinal products
Authors: Paliwal Bharat , Purohit Anamika 
Published: October 2016

SummaryHyperimmunoglobin E, or Job syndrome, is a rare primary immunodeficiency syndrome with characteristic facies, raised IgE levels and recurrent infections. We encountered a case where a patient requiring an emergency caesarean section was diagnosed with the syndrome and co‐incidentally was also found to be allergic to medically used plastics. Polyvinyl chloride (PVC)/diethylhexyl phthalate (DEHP) is the plastic used in manufacturing many medical devices. Concerns have been expressed regarding PVC/DEHP‐containing medical devices because they have been found to be toxic in experimental studies. There have been reports of mild reactions in the form of rashes or itching but true allergy to plastic or to the plasticiser with systemic manifestations has not been reported before.
The Kasai procedure in a baby with complex congenital heart disease
Authors: Goonasekera Chulananda , Cooper Mariese , Hill Cathie , Bansal Sanjay , Davenport Mark 
Published: October 2016

SummaryAdvances in medicine mean that increasing numbers of children with complex congenital heart disease are presenting for major non‐cardiac surgery. We describe a 2 month old male with complex congenital heart disease who underwent urgent Kasai surgery. He had a 'fixed' right to left shunt, via a left sided superior vena cava draining into the left atrium, and bi‐directional shunts via atrial and ventricular septal defects. We used a vasopressor as part of the anaesthetic technique in order to maintain shunt directions during surgery and postoperatively.
The soiled paediatric airway ‐ a case report and literature review of massive soil aspiration
Authors: Phipps Sarah , Rusk David 
Published: October 2016

SummaryMassive aspiration of garden soil is a rare but potentially fatal event in children. Definitive hospital management requires collaborative multidisciplinary care. We present the case of an 11‐month old who suffered massive aspiration of soil after pulling the contents of a large pot plant onto himself. We discuss recommended initial airway management, definitive soil removal techniques, and the role of steroids, antibiotics and tetanus prophylaxis in such cases. We also outline potential long‐term sequelae and highlight the need for long‐term follow‐up. Treatment priorities for such events can be summarised as: optimisation of airway and gas exchange whilst minimising passage of further material past the vocal cords, definitive removal of macroscopic soil from the larger respiratory passages, supportive respiratory care whilst assisting the muco‐ciliary mechanism to clear remaining soil and antibiotic and parasitic cover to prevent respiratory infection and long‐term sequelae.
The THRIVE technique to safely prolong the apnoeic window in a patient with a compromised airway
Authors: Lam Wai , Stolady Daniel , Balakrishnan Ramachandran 
Published: October 2016

SummaryWe present the anaesthetic management of a 66‐yr‐old male with a severely compromised airway. We describe successful utilisation of the Transnasal Humidified Rapid‐Insufflation Ventilatory Exchange (THRIVE) technique for pre‐oxygenation and provision of apnoeic oxygenation during anaesthetic induction. This technique extends the safe apnoeic period, reducing the risk of oxygen desaturation and allowing time for management of the airway.
Unilateral postoperative visual loss following prone positioning
Authors: Barrett Thomas , Webster Simon , Ferris John 
Published: October 2016

SummaryPeri‐operative visual loss following general anaesthesia is a potentially devastating complication of surgery. Its aetiology is variable and multifactoral. We describe an unusual, and previously unreported, cause of temporary peri‐operative visual loss in a patient undergoing orthopaedic surgery in the prone position. We highlight the importance of illiciting a history of previous ophthalmic surgery during the pre‐operative assessment in a patient due to undergo prone surgery and discussing the possibility of peri‐operative visual loss at this stage.
The Analysis of Network Governance in The Investment Development of Free Trade Zone and Free Port (KPBPB) Batam
Authors: Muzwardi Ady 
Published: October 2016

Large amount of investment is one of income sources for a country. Recently, the investment in Indonesia has not been managed optimally due to, one among others, poor organization system of investment management. This study is aimed at analyzing the network governance within organization system in investment development at Free Trade Zone and Free Port Batam. The research methodology used was Coordination Network Analysis with 5 aspects of study; those are governance structure, service characteristics, operational interaction of partner characteristics, and network characteristic on 3 organizations at the level of province and regency/city. The result of the analysis indicates that coordination between provincial and regency/city organizations is not yet optimally conducted. Horizontal and vertical coordination are not yet optimally established.
Development of a Standardized Rating Tool for Drug Alerts to Reduce Information Overload
Authors: Pfistermeister Barbara , Sedlmayr Brita , Patapovas Andrius , Suttner Gerald , Tektas Ozan , Tarkhov Aleksey , Kornhuber Johannes , Fromm Martin , Bürkle Thomas , Prokosch Hans-Ulrich , Maas Renke 
Published: October 2016

Summary
Background: A well-known problem in current clinical decision support systems (CDSS) is the high number of alerts, which are often medically incorrect or irrelevant. This may lead to the so-called alert fatigue, an over -riding of alerts, including those that are clinically relevant, and underuse of CDSS in general.
Objectives: The aim of our study was to develop and to apply a standardized tool that allows its users to evaluate the quality of system-generated drug alerts. The users’ ratings can subsequently be used to derive recommendations for developing a filter function to reduce irrelevant alerts.
Methods: We developed a rating tool for drug alerts and performed a web-based evaluation study that also included a user review of alerts. In this study the following categories were evaluated: “data linked correctly”, “medically correct”, “action required”, “medication change”, “critical alert”, “information gained” and “show again”. For this purpose, 20 anonymized clinical cases were randomly selected and displayed in our customized CDSS research prototype, which used the summary of product characteristics (SPC) for alert generation. All the alerts that were provided were evaluated by 13 physicians. The users’ ratings were used to derive a filtering algorithm to reduce overalerting.
Results: In total, our CDSS research prototype generated 399 alerts. In 98 % of all alerts, medication data were rated as linked correctly to drug information; in 93 %, the alerts were assessed as “medically correct”; 19.5 % of all alerts were rated as “show again”. The interrater-agreement was, on average, 68.4 %. After the application of our filtering algorithm, the rate of alerts that should be shown again decreased to 14.8 %.
Conclusions: The new standardized rating tool supports a standardized feedback of user-perceived clinical relevance of CDSS alerts. Overall, the results indicated that physicians may consider the majority of alerts formally correct but clinically irrelevant and override them. Filtering may help to reduce overalerting and increase the specificity of a CDSS.
Optimized R functions for analysis of ecological community data using the R virtual laboratory (RvLab)
Authors: Varsos Constantinos , Patkos Theodore , Oulas Anastasis , Pavloudi Christina , Gougousis Alexandros , Ijaz Umer , Filiopoulou Irene , Pattakos Nikolaos , Vanden Berghe Edward , Fernández-Guerra Antonio , Faulwetter Sarah , Chatzinikolaou Eva , Pafilis Evangelos , Bekiari Chryssoula , Doerr Martin , Arvanitidis Christos 
Published: October 2016

Parallel data manipulation using R has previously been addressed by members of the R community, however most of these studies produce ad hoc solutions that are not readily available to the average R user. Our targeted users, ranging from the expert ecologist/microbiologists to computational biologists, often experience difficulties in finding optimal ways to exploit the full capacity of their computational resources. In addition, improving performance of commonly used R scripts becomes increasingly difficult especially with large datasets. Furthermore, the implementations described here can be of significant interest to expert bioinformaticians or R developers. Therefore, our goals can be summarized as: (i) description of a complete methodology for the analysis of large datasets by combining capabilities of diverse R packages, (ii) presentation of their application through a virtual R laboratory (RvLab) that makes execution of complex functions and visualization of results easy and readily available to the end-user.
In this paper, the novelty stems from implementations of parallel methodologies which rely on the processing of data on different levels of abstraction and the availability of these processes through an integrated portal. Parallel implementation R packages, such as the pbdMPI (Programming with Big Data – Interface to MPI) package, are used to implement Single Program Multiple Data (SPMD) parallelization on primitive mathematical operations, allowing for interplay with functions of the vegan package. The dplyr and RPostgreSQL R packages are further integrated offering connections to dataframe like objects (databases) as secondary storage solutions whenever memory demands exceed available RAM resources.
The RvLab is running on a PC cluster, using version 3.1.2 (2014-10-31) on a x86_64-pc-linux-gnu (64-bit) platform, and offers an intuitive virtual environmet interface enabling users to perform analysis of ecological and microbial communities based on optimized vegan functions.
A beta version of the RvLab is available after registration at: https://portal.lifewatchgreece.eu/
Micro-CTvlab: A web based virtual gallery of biological specimens using X-ray microtomography (micro-CT)
Authors: Keklikoglou Kleoniki , Faulwetter Sarah , Chatzinikolaou Eva , Michalakis Nikitas , Filiopoulou Irene , Minadakis Nikos , Panteri Emmanouela , Perantinos George , Gougousis Alexandros , Arvanitidis Christos 
Published: October 2016

During recent years, X-ray microtomography (micro-CT) has seen an increasing use in biological research areas, such as functional morphology, taxonomy, evolutionary biology and developmental research. Micro-CT is a technology which uses X-rays to create sub-micron resolution images of external and internal features of specimens. These images can then be rendered in a three-dimensional space and used for qualitative and quantitative 3D analyses. However, the online exploration and dissemination of micro-CT datasets are rarely made available to the public due to their large size and a lack of dedicated online platforms for the interactive manipulation of 3D data. Here, the development of a virtual micro-CT laboratory (Micro-CTvlab) is described, which can be used by everyone who is interested in digitisation methods and biological collections and aims at making the micro-CT data exploration of natural history specimens freely available over the internet.
The Micro-CTvlab offers to the user virtual image galleries of various taxa which can be displayed and downloaded through a web application. With a few clicks, accurate, detailed and three-dimensional models of species can be studied and virtually dissected without destroying the actual specimen. The data and functions of the Micro-CTvlab can be accessed either on a normal computer or through a dedicated version for mobile devices.
ERP et profil d’activités du contrôleur de gestion : une évolution par paliers ?
Authors: Mawadia Anass , Chapellier Philippe , Eggrickx Ariel 
Published: October 2016

Cet article étudie l’ évolution du profil d’activités des contrôleurs de gestion après la mise en place d’un ERP ( Enterprise Resource planning ). Il s’appuie sur le modèle de Besson (1999) qui dresse les profils d’activités des contrôleurs de gestion avant et après la mise en place d’un ERP. Une enquête a été réalisée par questionnaire, puis par entretiens directs, dans une entreprise multinationale ayant mis en place l’ERP JD Edwards. Si l’ERP participe à l’évolution du profil d’activités du contrôleur de gestion, la mutation du métier vers un rôle de support au pilotage suppose une double condition : la mise en place d’outils de business intelligence et une volonté forte de la direction.
La nouvelle délégation parlementaire au renseignement va-t-elle améliorer l’efficacité des services ?
Authors: Junghans Pascal 
Published: October 2016

Depuis une loi du 9 octobre 2007, les services de renseignement des ministères de la Défense, de l’Intérieur, de l’Économie et des Finances sont suivis par une délégation parlementaire au renseignement. Cette délégation pourrait améliorer l’efficacité des services. Toutefois, comme dans les autres pays démocratiques qui en disposent, ce « contrôle » parlementaire peut engendrer de redoutables dérives.
Q-Methodology: An Alternative Design for Undergraduate Nursing Honors Research
Authors: Hensel Desiree 
Published: October 2016

Background:
Undergraduate research is a high-impact educational practice that fosters deep learning. Study design is an important factor to consider when planning for student success.

Method:
Q-methodology uses statistical principles to study subjectivity and can be successfully used by undergraduate nursing students to build research skills and foster deep learning.

Results:
Authentic assessments evidencing attainment of the desired learning outcomes in student studies include well-written literature reviews, successful institutional review board submissions, completed projects, and dissemination of findings.

Conclusion:

Q-studies solve many design challenges faced by novice researchers leading to doable and meaningful undergraduate projects. [
J Nurs Educ
. 2016;55(11):659–662.]
Development of Monofixation Syndrome After Extraction of Dense Cataracts
Authors: Eustis H. Sprague , Janot Adam , Jhaveri Chirag 
Published: October 2016

Purpose:
If the interruption of macular fusion for an extended period of time is the key event that results in the development of monofixation syndrome, then the decreased macular input caused by dense cataracts may cause monofixation syndrome in adults. This study was designed to test this hypothesis.

Methods:
The study design was a retrospective chart review that identified patients with unilateral cataracts at two southern Louisiana medical centers. Patients were assigned to the dense cataract group if a unilateral cataract had been present for at least 3 months and led to a visual acuity of worse than 20/200. Patients in the control group had a unilateral cataract for more than 3 months and visual acuity better than 20/200 in the affected eye. Stereoacuity was assessed using the Titmus or Randot stereo test. A Worth 4-dot test viewed at a distance of 20 feet was used to assess the presence of a macular scotoma. The criteria for monofixation syndrome were met if stereoacuity was less than 60 seconds and the Worth 4-dot test demonstrated central macular scotoma at 20 feet.

Results:

The dense cataract group's association with monofixation syndrome was statistically significant when compared to the control group (
P
< .0001).

Conclusions:
This study adds dense adult-onset cataracts to the list of causes of monofixation syndrome and reduced stereoacuity. A delay in treating dense lens opacities can result in good visual outcome but an inferior binocular visual outcome (poor stereoacuity).

[
J Pediatr Ophthalmol Strabismus
. 2017;54(1):39–42.]
Outcomes of Two Surgical Techniques Using Silicone Rod for Frontalis Sling Suspension to Treat Severe Ptosis
Authors: Galindo-Ferreiro Alicia , Akaishi Patricia , Hanafi Somaya , Khandekar Rajiv , Galvez-Ruiz Alberto , Schellini Silvana , Cruz Augusto 
Published: October 2016

Purpose:
To compare outcomes of two techniques of frontalis silicone sling surgery.

Methods:
This retrospective, nonrandomized chart review was performed on patients undergoing frontalis sling surgery between 2008 and 2011. Silicone rods were sutured to the tarsal plate through an eyelid crease incision (open method) or stab incisions (closed method). Data were collected on age, gender, type of surgery, preoperative and postoperative margin reflex distance (MRD), and complications. A successful outcome was defined as a postoperative score of 2 to 4 for MRD or an improvement in MRD.

Results:
A total of 155 eyelids of 146 patients with ptosis were included. There were 60 patients in the open method group and 85 patients in the closed method group, respectively. Successful outcomes were seen in 30 (50%) patients in the open method and 44 (51.8%) patients in the closed method groups. There were 61 (71.8%) patients in the open method group and 45 (75%) patients in the closed method group who had improved MRD at last follow-up. The main complications were exposure keratitis, eyelash ptosis, and eyelid crease abnormalities that occurred only in the closed method group.

Conclusions:
The silicone frontalis sling procedure had the same success rates in both the open and closed methods. Eyelash and eyelid crease abnormalities were unique to the closed method.

[
J Pediatr Ophthalmol Strabismus
. 2017;54(1):52–58.]