bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intelligent Cobweb Structures for All‐In‐One Flexible Devices via Laser Thermal Printing
Authors: Yi Longju , Zhao Yilin , Li Yunfan , Guo Dingyi , Zeng Ziran , Liu Zhe , Zheng Huai , Cheng Gary J. , Liu Feng 
Published: September 2024

AbstractA novel laser thermal printing technique toward the fabrication of all‐in‐one flexible intelligent devices is presented in this work, addressing the existing challenges in their scalable manufacturing and multifunctional performance. The first‐ever application of this technique for the synthesis of a multifunctional intelligent cobweb structure is presented. The resultant cobweb integrates a conductive network of multi‐walled carbon nanotubes (MWCNTs) and NdFeB magnetic microparticles within a polydimethylsiloxane (PDMS) matrix, enabling seamless incorporation of sensing, stimulus response, and actuation functionalities. The cobweb exhibits multifunctional sensing characteristics, including a 2.37 strain gauge factor and a 0.312%·mT−1 magnetic field sensitivity, excellent stability exceeding 3500 cycles. Furthermore, the cobweb achieves accurate capture of a beetle on the basis of real‐time sensing of the beetle, verifying its rapid stimulus response characteristics. Meanwhile, the cobweb exhibits an electromagnetic ejection performance with an ejection height of over 33.5 times the size of the projectile, verifying its powerful actuating ability. These results demonstrate the successful integration of multifunctional sensing, stimulus response, and actuation within the cobweb structure, facilitated by the innovative laser thermal printing process. The laser thermal printing technique marks a significant advancement in the efficient fabrication of miniaturized and multifunctional flexible intelligent devices based on thermosetting materials.
Integration of Functional Polymers and Biosensors to Enhance Wound Healing
Authors: Basu Proma , Banerjee Aihik , Okoro Prince David , Masoumi Arameh , Kanjilal Baishali , Akbari Mohsen , Martins‐Green Manuela , Armstrong David G. , Noshadi Iman 
Published: September 2024

AbstractBiosensors have led to breakthroughs in the treatment of chronic wounds. Since the discovery of the oxygen electrode by Clarke, biosensors have evolved into the design of smart bandages that dispense drugs to treat wounds in response to physiological factors, such as pH or glucose concentration, which indicate pathogenic tendencies. Aptamer‐based biosensors have helped identify and characterize pathogenic bacteria in wounds that often form antibiotic‐resistant biofilms. Several functional polymers have served as indispensable parts of the fabrication of these biosensors. Beginning with natural polymers such as alginate, chitosan, and silk‐based fibroin, which are biodegradable and absorptive, advances have been made in formulating biocompatible synthetic polymers such as polyurethane and polyethylene glycol designed to reduce non‐specific binding of proteins and cells, making biosensors less painful or cumbersome for patient use. Recently, polycaprolactone has been developed, which offers ductility and a large surface‐area‐to‐volume ratio. There is still room for advances in the fabrication and use of biosensors for wound healing and in this review, the trend in developing biosensors from biomarker detection to smart dressings to the incorporation of machine learning in designing customized wound patches while making application easier is highlighted and can be used for a long time.
Impact of Drug Conjugation Site and Corona Chemistry on the Therapeutic Activity of Polymer Nanorod – Drug Conjugates
Authors: Warne Nicole M. , Nowell Cameron J. , Tran Mai P. , Finnegan John R. , Feeney Orlagh M. , Kempe Kristian 
Published: September 2024

AbstractBiocompatible rod‐shaped nanoparticles of controlled length can be produced through the heat‐induced “living” seeded crystallization‐driven self‐assembly (CDSA) of poly(2‐isopropyl‐2‐oxazoline)‐containing block copolymers. With a hydrophilic poly(2‐methyl‐2‐oxazine) or poly(2‐methyl‐2‐oxazoline) corona, these nanorods have proven non‐cytotoxic, non‐hemolytic, and ideal for use as a polymer‐based drug delivery system. This study demonstrates a facile, one‐pot method for the synthesis of mycophenolic acid (MPA)‐conjugated block copolymer “unimers” for use in seeded CDSA. Through altering block order during sequential monomer addition cationic ring‐opening polymerization (CROP), MPA is conjugated to either the chain end of the core‐forming or corona‐forming block. This allows bioactive polymer nanorods to be prepared with MPA positioned at either the periphery of the corona, or at the core‐corona interface of the nanorod formed during seeded CDSA. In vitro, these nanorods arrest growth in human T and B lymphocytes, with reduced effect in “off‐target” monocytes when compared with unconjugated MPA. Furthermore, the conjugation of MPA to the core‐corona interface of the nanorods leads to a slower release and reduced cytostatic effect. This study offers a robust investigation into the effect of steric hindrance and corona chemistry on the therapeutic potential of drug‐conjugated CDSA nanorods and demonstrates the potential of poly(2‐oxazoline)/poly(2‐oxazine)‐based CDSA nanomaterials as effective drug delivery platforms.
Multiple‐Effect Combined Hydrogels: “Temporal Regulation” Treatment of Osteosarcoma‐Associated Bone Defects with Switchable Hyperthermia and Bioactive Agents
Authors: Li Lin , Lin Yating , Liu Kun , Huang Runshan , Wen Wei , Huang Yadong , Liu Mingxian , Zhou Changren , Ding Shan , Luo Binghong 
Published: September 2024

AbstractAchieving the clinically staged treatment of osteosarcoma‐associated bone defects encounters the multiple challenges of promptly removing postoperative residual tumor cells and bacterial infection, followed by bone reconstruction. Herein, a core/shell hydrogel with multiple‐effect combination is designed to first exert antitumor and antibacterial activities and then promote osteogenesis. Specifically, doxorubicin (DOX) is loaded by magnesium‐iron‐based layered double hydroxide (LDH) to prepare LDOX, which is introduced into a thermo‐sensitive hydrogel to serve as an outer shell of the core/shell hydrogel, meanwhile, LDH‐contained liquid crystal hydrogel, abbreviated as LCgel‐L, is served as an inner core. At the early stage of treatment, the dissociation of the outer shell triggered by moderate hyperthermia led to the thermo‐sensitive release of LDOX, which can be targeted for the release of DOX within tumor cells, thereby promptly removing postoperative residual tumor cells based on the synergistic effect of photothermal therapy (PTT) and DOX, and postoperative bacterial infection can also be effectively prevented by PTT simultaneously. More importantly, the dissociation of the outer shell prompted the full exposure of the inner core, which will exert osteogenic activity based on the synergy of liquid crystal hydrogel as well as LDH‐induced mild hyperthermia and ion effects, thereby enabling “temporal regulation” treatment of osteosarcoma‐associated bone defects. This study provides a valuable insight for the development of osteosarcoma‐associated bone repair materials.
Highly Efficient and Stable Perovskite Solar Modules Based on FcPF6 Engineered Spiro‐OMeTAD Hole Transporting Layer
Authors: Chang Qing , Yun Yikai , Cao Kexin , Yao Wenlong , Huang Xiaofeng , He Peng , Shen Yang , Zhao Zhengjing , Chen Mengyu , Li Cheng , Wu Binghui , Yin Jun , Zhao Zhiguo , Li Jing , Zheng Nanfeng 
Published: September 2024

AbstractLi‐TFSI doped spiro‐OMeTAD is widely recognized as a beneficial hole transport layer (HTL) in perovskite solar cells (PSCs), contributing to high device efficiencies. However, the uncontrolled migration of lithium ions (Li+) during device operation has impeded its broad adoption in scalable and stable photovoltaic modules. Herein, an additive strategy is proposed by employing ferrocenium hexafluorophosphate (FcPF6) as a relay medium to enhance the hole extraction capability of the spiro‐OMeTAD via the instant oxidation function. Besides, the novel Fc–Li interaction effectively restricts the movement of Li+. Simultaneously, the dissociative hexafluorophosphate group is cleverly exploited to regulate the unstable iodide species on the perovskite surface, further inhibiting the formation of migration channels and stabilizing the interfaces. This modification leads to power conversion efficiencies (PCEs) reaching 22.13% and 20.27% in 36 cm2 (active area of 18 cm2) and 100 cm2 (active area of 56 cm2) perovskite solar modules (PSMs), respectively, with exceptional operational stability obtained for over 1000 h under the ISOS‐L‐1 procedure. The novel FcPF6‐based engineering approach is pivotal for advancing the industrialization of PSCs, particularly those relying on high‐performance spiro‐OMeTAD‐ based HTLs.
Solar‐to‐NIR Light Activable PHBV/ICG Nanofiber‐Based Face Masks with On‐Demand Combined Photothermal and Photodynamic Antibacterial Properties
Authors: Haghighat Bayan Mohammad Ali , Rinoldi Chiara , Kosik‐Kozioł Alicja , Bartolewska Magdalena , Rybak Daniel , Zargarian Seyed Shahrooz , Shah Syed Ahmed , Krysiak Zuzanna J. , Zhang Shichao , Lanzi Massimiliano , Nakielski Paweł , Ding Bin , Pierini Filippo 
Published: September 2024

AbstractHierarchical nanostructures fabricate by electrospinning in combination with light‐responsive agents offer promising scenarios for developing novel activable antibacterial interfaces. This study introduces an innovative antibacterial face mask developed from poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) (PHBV) nanofibers integrated with indocyanine green (ICG), targeting the urgent need for effective antimicrobial protection for community health workers. The research focuses on fabricating and characterizing this nanofibrous material, evaluating the mask's mechanical and chemical properties, investigating its particle filtration, and assessing antibacterial efficacy under photothermal conditions for reactive oxygen species (ROS) generation. The PHBV/ICG nanofibers are produced using an electrospinning process, and the nanofibrous construct's morphology, structure, and photothermal response are investigated. The antibacterial efficacy of the nanofibers is tested, and substantial bacterial inactivation under both near‐infrared (NIR) and solar irradiation is demonstrated due to the photothermal response of the nanofibers. The material's photothermal response is further analyzed under cyclic irradiation to simulate real‐world conditions, confirming its durability and consistency. This study highlights the synergistic impact of PHBV and ICG in enhancing antibacterial activity, presenting a biocompatible and environmentally friendly solution. These findings offer a promising path for developing innovative face masks that contribute significantly to the field of antibacterial materials and solve critical public health challenges.
Asymmetric Addition of Allomaltol to Chalcones and Bis(arylidene)acetones: En Route to Chiral Drugs
Authors: Kovalevsky Ruslan A. , Kucherenko Alexander S. , Zlotin Sergei G. 
Published: September 2024

AbstractThe synthesis of enantiomerically enriched γ‐oxobutyric acid and succinic acid derivatives based on asymmetric conjugate addition of allomaltol to chalcones or bis(arylidene)acetones in the presence of readily available and recoverable C2‐symmetric tertiary amine‐squaramide organocatalyst has been developed. Ru(III)‐catalyzed oxidative transformation of pyran‐4‐ones bearing the α,β‐enone unit to enantiomerically enriched succinic acid derivatives via a one‐pot oxidative fragmentation of both the γ‐pyrone ring and activated C=C bond has been elaborated. The developed methodology was applied for scalable asymmetric synthesis of GABAB receptor agonists precursors, RAR receptor agonists and monoaminooxidase (MAO) inhibitors.
Global Analysis of Combined Photovoltaic Green and Cool Roofs Under Climate Change
Authors: Hassoun Lina , Cook Lauren M. 
Published: September 2024

AbstractSustainable roofing configurations, including green and white roofs, can reduce rooftop surface temperatures compared to conventional surfaces and can therefore enhance photovoltaic (PV) system performance due to the temperature dependence of PV cells. Previous research, primarily experimental, recognized the synergy of combining PV with green or cool roofs. However, the influence of geographic and climatic factors on the performance of these combined systems, particularly in future climates affected by climate change, remains unclear. This work integrates three roof configurations (gravel, green, and white) into rooftop solar energy modeling across thirteen cities with different climate types, under current and future climate scenarios. Results indicate limited efficiency gains (< 2%) across all cities and climates, challenging previous findings. Yield is expected to increase in some cities receiving more solar irradiation in the future but decrease in others due to rising temperatures. Green and cool roofs can partially offset the effects of climate change on yield. PV‐white roofs consistently outperform PV‐green roofs, with the performance gap expected to widen in future climates. PV‐green roofs excel in tropical climates with high irradiation and precipitation levels. Overall, the outcomes of this study inform the design and planning of sustainable buildings in response to climate change challenges.
Cross‐Species Insights into Trophoblast Invasion During Placentation Governed by Immune‐Featured Trophoblast Cells
Authors: Zang Xupeng , Zhang Dan , Wang Wenjing , Ding Yue , Wang Yongzhong , Gu Shengchen , Shang Yijun , Gan Jianyu , Jiang Lei , Meng Fanming , Shi Junsong , Xu Zheng , Huang Sixiu , Li Zicong , Wu Zhenfang , Gu Ting , Cai Gengyuan , Hong Linjun 
Published: September 2024

AbstractProper development of the placenta, the transient support organ forms after embryo implantation, is essential for a successful pregnancy. However, the regulation of trophoblast invasion, which is most important during placentation, remains largely unknown. Here, rats, mice, and pigs are used as biomedical models, used scRNA‐seq to comparatively elucidate the regulatory mechanism of placental trophoblast invasion, and verified it using a human preeclampsia disease model combined with scStereo‐seq. A dual‐featured type of immune‐featured trophoblast (iTrophoblast) is unexpectedly discovered. Interestingly, iTrophoblast only exists in invasive placentas and regulates trophoblast invasion during placentation. In a normally developing placenta, iTrophoblast gradually transforms from an immature state into a functional mature state as it develops. Whereas in the developmentally abnormal preeclamptic placenta, disordered iTrophoblast transformation leads to the accumulation of immature iTrophoblasts, thereby disrupting trophoblast invasion and ultimately leading to the progression of preeclampsia.
The Exceptionally High Dielectric Constant of Doped Organic Semiconductors
Authors: Yang Xuwen , Liu Jian , Koster L. Jan Anton 
Published: September 2024

AbstractThe dielectric constant (ɛr) is an essential parameter as it characterizes the ability to screen charge. Molecular doping is a key strategy to enhance the electronic properties of organic semiconductors, where again ɛr is important because the Coulomb attraction introduced by dopants needs to be overcome to generate carriers. Previous theoretical work has reported collective screening can lead to a dramatic enhancement of ɛr upon doping. Whereas this prediction has been tested in the low‐doping regime, the predicted dielectric catastrophe remains unexplored. Here, metal‐insulator‐semiconductor (MIS) diodes to measure the dielectric constant of organic semiconductors subjected to moderate‐to‐high doping levels is employed. MIS diodes make it possible to measure the dielectric constant at relatively high doping ratios and corresponding high electrical conductivities. This results demonstrated a notable rise in the dielectric constant within a range of ≈3.0–15.0 of n‐ and p‐doped organic semiconductors, resembling the phenomenon of dielectric catastrophe. These observations align with recent theoretical investigations into the impact of molecular doping on ɛr and show the collective behavior of free charges in doped organic semiconductors.
Unusual Magnetocaloric Effect Triggered by Spin Reorientation
Authors: Song Yuzhu , Zhang Jimin , Li Hengchao , Zhong Hong , Long Feixiang , Wang Zhan , Xu Yuanji , Zheng Xinqi , Zhang Hu , Huang Qingzhen , Zhang Ying , Xing Xianran , Chen Jun 
Published: September 2024

AbstractAdvancements and utilization of magnetic refrigeration technology hinge on the ongoing enhancement and optimization of magnetic refrigeration material properties. Nevertheless, the intricacy of the magnetocaloric effect (MCE) mechanism has emerged as a bottleneck, constraining the progress and refinement of magnetic refrigeration materials. In this study, a classic magnetic system is chosen to investigate the mechanism of MCE across four different scales–macroscopic magnetism, micrometer‐scale magnetic domains, atomic magnetic moments, and electronic structure. It simultaneously exhibits two inverse MCEs and one direct MCE, with a working temperature span as wide as 125 K (most are <50 K) for the direct MCE. The measurements of the vibrating sample magnetometer, in situ Lorentz electron microscopy and variable‐temperature neutron powder diffraction directly reveal that the complex magnetic entropy changes arise from the magnetic domain wall pinning, the instability of Ho magnetic moments, and the spin rotation. First‐principles calculations elucidate the crucial role of strong hybridization between localized Ho and itinerant Co electrons in the spin reorientation of HoCo4Al. This study contributes significantly to comprehending the induction mechanism of the MCE and holds vital reference value for exploring new magnetic refrigeration materials and enhancing MCE performance.
Advances and Prospects of Carbon Dots for High‐Performance Zinc‐Based Batteries
Authors: Zhang Zekun , Zhou Xuelian , Dong Jia , Xue Taotao , Di Yingran , Li Bin , Zhao Ningning , Dai Lei , Wang Ling , He Zhangxing 
Published: September 2024

AbstractZinc‐based batteries are emerging as the most promising candidates for large‐scale energy storage devices due to their low cost, high safety, and long‐term storage. However, zinc‐based batteries encounter challenges stemming from undesirable side reactions and zinc dendrites on the anode, as well as dissolution on the cathode. Owing to their extremely small size, substantial surface functional groups, and adjustable structure, carbon dots (CDs) present considerable benefits in augmenting coulombic efficiency, expanding cycle life, and enhancing the rate functionality of zinc‐based batteries. Herein, this review delves into the surface modification and morphological regulation of batteries elements by CDs, CDs composites, and CDs derivatives. Moreover, it systematically encapsulates the application of CDs in zinc‐based batteries, underscoring the pivotal role of CDs in the advancement of electrode technology. Finally, the review highlights the impediments and proposes potential avenues for utilizing CDs in zinc‐based batteries. This review aims to facilitate the development of superior solutions and provide scientific insights into energy storage technologies.
The uptake of dissolved glucose by juvenile green‐lipped mussels (Perna canaliculus)
Authors: Jordan Andy , Skelton Brad , Mugica Maria , Jeffs Andrew 
Published: September 2024

AbstractA major expense in the operation of bivalve nurseries is the culture of high‐quality live microalgae feeds, and efforts to develop effective alternative feeds have had limited success. Juvenile bivalves are known to be able to absorb dissolved nutrients, but this ability has received minimal attention as a route for supplementary feeding. This study assessed the capacity of juvenile green‐lipped mussels (GLMs) (Perna canaliculus) to uptake and assimilate dissolved glucose at five experimental concentrations (i.e. 10 µg mL−1, 100 µg mL−1, 1 mg mL−1, 10 mg mL−1 and 30 mg mL−1) as a supplement to cultured microalgae. Growth and survival of the mussels were measured over 3 weeks. Although all glucose concentrations improved the performance of mussel spat compared to the control, the best performing was a concentration of 1 mg mL−1 of dissolved glucose which enhanced daily spat growth 2.7 times that of the control live microalgal diet without glucose. Survival was high (i.e. >95%) for all treatments except for the highest experimental concentration of glucose, for which a concentration of 30 mg mL−1 resulted in mean mortality of 24%. Mussel spat supplemented with dissolved glucose accumulated up to 30% greater lipid and improved the carbohydrate content per mg g−1 of ash‐free dry weight as much as 3.5 times compared to those in the control treatment, indicating that they were in greater nutritional condition. This demonstration that dissolved glucose can be used to fuel growth by GLM spat at concentrations as low as 10 µg mL−1 suggests that other soluble nutrients may also act as a supplemental feed for cultured juvenile molluscs. Dissolved nutrients have the potential to improve the performance of spat in nursery systems while simultaneously reducing the reliance of cultured microalgae as a sole feed input.
Long‐term tillage and residue removal effects on soil carbon, nitrogen, and grain yield in irrigated corn
Authors: Schmer Marty R. , Ramirez Salvador , Jin Virginia L. , Wienhold Brian J. , Varvel Gary E. , Willhelm Wally W. 
Published: September 2024

AbstractCorn (Zea mays L.) stover demand as a forage or for an emerging bioeconomy has increased the importance of determining the long‐term effects of stover removal on grain yield and soil properties. Study objectives were to evaluate grain yield, soil organic carbon (SOC), and total soil N (0–150 cm) in a 20‐year, irrigated, continuous corn study, located in eastern Nebraska, under conventional tillage (CT) and no‐till (NT) with variable corn stover removal rates (none, medium, and high). After 20 years, grain yield was up to 6.0% greater under NT with stover removal compared with NT and no stover removal, while yield was similar for CT in all stover removal treatments. Grain yield was similar between NT with stover removal and CT in all stover removal treatments. High stover removal rates resulted in greater SOC loss at the surface soil layers (0–15 cm and 0–30 cm) after 20 years compared with no or medium stover removal. Corn stover retention under NT resulted in the same cumulative SOC stock loss as CT or stover removal. All management practices resulted in cumulative (0–120 cm) SOC stock loss (8% decrease) that occurred in the last 10 years of the study. Total soil nitrogen stocks were maintained or increased after 20 years at the surface soil layers (0–15 cm and 0–30 cm) and were similar between NT and CT. In an irrigated continuous corn system, neither NT nor stover retention was able to maintain cumulative SOC stocks over time.