bluuebunny/crossref_metadata_2025_split huggingface dataset:
Achieving predictable contacts and contours: A review
Authors: Tyagi Shivali , Rathi Shravan , Nikhil Vineeta 
Published: September 2024

Restoring surface cavities and replacing the lost tooth structure from caries, trauma, decay, damage and other causes to their natural anatomy is one of the main objective of restorative dentist. Enhanced comprehension of the interproximal relationship enables clinicians to more effectively preserve or restore these structures. To preserve the natural form of the tooth while restoring, the shape and contour of restoration can be given by various matrix systems. This paper is an attempt not only to make the reader understand about the normal anatomic contacts and contours and various matrix system available recently but also it helps the clinician to select the best matrix system for the specific clinical situation to achieve predictable contacts and contour to enhance longevity of dental restorations.Importance of use of matrix band in clinical dentistry for obtaining ideal contacts and contours.
Non-surgical management of mandibular first premolar with vertucci type v root canal configuration: A case report
Authors: Azeez Mohd Faisal , Mittal Neelam , Sharma Shelly 
Published: September 2024

Mandibular premolars are known for having a complex anatomy, often considered as enigma to endodontist. Thorough knowledge of the root canal morphology, appropriate assessment of the pulp chamber floor and proper interpretation of radiograph is a prerequisite for successful root canal therapy. The complex anatomy and morphology of root canals can be classified according to VERTUCCI root canal classification system. VERTUCCI type V is a characterization given to a root where a canal is divided into two separate root canals with two separate apical foramina. Such type of cases with complex anatomy of the root canal can be successfully managed if the clinician has thorough knowledge of root canals.
The Role of Bone Grafting vs. Bone Cement in the Treatment of Giant Cell Tumor of Bone
Authors: Costello Joseph P. , Travis Levi M. , Jahn Jacob , Pretell-Mazzini Juan A. 
Published: September 2024

Background:
Giant cell tumor of bone (GCTB) presents a challenge in management due to its invasive nature and propensity for local recurrence. While either bone grafting (BG) or bone cement (BC) can be utilized to fill defects after intralesional curettage, the optimal treatment remains contested. The purpose of this study was to examine the impact of defect filling with BC compared with BG on recurrence rates in patients with GCTB following intralesional curettage.

Methods:
A random-effects model binary outcome meta-analysis was performed utilizing recurrence rate for the BC and BG groups to evaluate the risk ratio (p < 0.05 considered significant). There were 1,454 patients included.

Results:
Intralesional curettage with BG had a recurrence risk ratio of 1.68 (95% confidence interval [CI], 1.22-2.31, p = 0.001) when compared with BC. The overall rate of recurrence for GCTB after intralesional curettage with BC was 20.05% vs. 29.74% with BG (95% CI, 0.17-0.23 vs. 0.26-0.33, p < 0.001).

Conclusion:
Intralesional curettage with BC for the treatment of GCTB demonstrated lower recurrence rates than intralesional curettage with BG. However, the rates of recurrence remain substantial for both groups, necessitating careful consideration of the benefits and potential pitfalls associated with BC vs. BG when considering salvage options after recurrences.

Level of Evidence:

Level III. See Instructions for Authors for a complete description of levels of evidence.
Analysis of The Influence of Work Discipline And Employee Motivation on Employee Performance BMT Beringharjo
Authors: Astuti Rahma Yudi , Mahdi Muhammad Wafiyuddin Balya 
Published: September 2024

Human resources (HR) will play a positive or negative role in the performance of a company by applying work discipline and work motivation. However, BMT Beringharjo Still long work motivations based on Islamic values to improve HR performance. In addition, the success of the company is largely determined by the style of work motivation that exists in the organization that will affect employee performance. BMT Beringharjo is an Islamic-based which implements in accordance with the company's VISION, namely "Leading bras trusted Sharia-Based business partner" in its company so as to improve employee performance. Therefore, this study will analyze how far the influence of work discipline in the organization and the work motivation retrered on improving the performance of BMT Beringharjo. This research uses a quantitative approach. The data collection technique used is primary data, by spreading questionnaires. Data was obtained from the employee population of 31 people. Data analysis using SPSS 26 which was analyzed deductively. The results of this study show that work discipline has a positive effect on employee performance with a sig of 0.002< 0.1, while Islamic work motivation has a positive effect on employee performance at BMT Beringharjo with a sig of 0.034< 0.1. With This result, the influence of work discipline and work motivation in it can get closer to Allah SWT through the practice carried out in every work in it. Recommendations for the company itself to always improve work discipline and work motivation in order to create an Islamic organizational culture in accordance with the existing vision, namely " Leading Bras, Trusted sharia Based business Sharia
Simulation and Experimental Validation of a New Separator Design for a Wide Range of Gas Volume Fractions
Authors: Zeng Xiaobo , Gao Li , Fan Guangming , Xu Yifan , Xiao Youhong , Yan Changqi 
Published: September 2024

Summary
For downhole gas-liquid separation, it is crucial to maintain high separation efficiency across a wide range of inlet gas volume fractions. In this paper, we present a numerical investigation into the flow field characteristics and separation mechanism of a new gas-liquid separator that utilizes centrifugal and gravity separation methods. An experimental system was built to validate the accuracy of the numerical model, and the numerical results show similar characteristics with experimental data in phase distribution as well as separation efficiency. In addition, we examine the impact of various operational parameters on the separation performance in this study. The findings indicate that the separator is capable of achieving a separation efficiency of approximately 100% within the inlet gas volume fraction range of 40–80%. Furthermore, it is crucial to control the liquid level to ensure effective separation of gas from the water layer. Altering the inlet liquid flow rate and gas volume fraction has a direct influence on the water content of the gas outlet, resulting in a decrease in separation efficiency. Consequently, optimization of the upper region of the separator is necessary to improve the separation performance.
Influence of H3K9 Methylation on Gene Mutation Rates: Advancing Epigenetic Research with Controlled Experimental Design
Authors: Abdalla Ola , Walker Cameron 
Published: September 2024

Abstract

Mutations drive genetic variation, fueling both oncogenesis and species evolution. The mutation rate varies across the genome, potentially influenced by chromatin organization through histone modifications and other factors. However, the precise relationship between chromatin structure and mutation rate remains poorly understood and needs further investigation. One such modification, the methylation of histone H3 at lysine 9 (H3K9me), is known to form heterochromatin and repress transcription in euchromatin, thereby maintaining genome stability essential for organism survival. This study aimed to elucidate the effect of H3K9 methylation, in isolation from other histone markers, on the mutation rate in fission yeast. Employing fluctuation assays and statistical analysis, our innovative methodology estimates the mutation rates of a single gene under two different conditions within a single experiment using an isogenic clone in Fission yeast. Our findings reveal that H3K9me2 markers significantly increase the phenotypic mutation rate of the same gene. For prospective researchers, this study introduces a new experimental approach that offers unprecedented accuracy in gene analysis, with implications for both genetic research and epigenetic therapy.
Cognitive Dynamics of Spontaneous Thought: A Novel Modeling Approach
Authors: Treadway Michael , Migó Marta , Cooper Jessica , Kragel Philip 
Published: September 2024

Abstract

The nature and frequency of spontaneous thoughts play a critical role in cognitive processes like perception, decision-making, attention, and memory. Deficits in these processes are also greatly associated with the development and maintenance of psychopathology. However, the underlying cognitive dynamics of free and stuck spontaneous thought remain unclear, as these often occur in the absence of measurable behaviors. Here, we analyze free word-association data using attractor-state dynamic modeling, which conceptualizes stuck spontaneous thought as navigating a multidimensional semantic space while in the presence of strong attractor locations. Word-association data was collected from an exploratory sample (N_1 = 65), a first replication sample (N_2 = 79), and, following pre-registration, a second replication sample (N_3 = 222). After the data was embedded into a 3-dimensional semantic space and fit by our dynamic model, unsupervised learning consistently grouped data into four clusters across all independent samples. These clusters were characterized by two distinct patterns of stuck negative thinking, a pattern of protective positive thinking, and a pattern of flexible mind-wandering. Our results support a novel method for modeling spontaneous thought and isolate distinct sub-types that may not be accessible using retrospective self-report methods. We discuss implications for clinical and cognitive science.
A preprogrammed force field generated in a confined space enables external-module-free anisotropic vat-photopolymerization 3D printing
Authors: Honda Satoshi 
Published: September 2024

Abstract

Additive Manufacturing, commonly known as 3D printing (3DP), continuously drives a paradigm shift in manufacturing processes from traditional mass production to individually optimized on-demand manufacturing. Vat-photopolymerization (VP) 3DP is a well-established methodology that enables highly precise high-speed modeling of intricate objects from photoresins with an inexpensive 3DP device. However, it remains a challenge to fabricate anisotropic objects without an external-field-applying module, which induces the alignment of molecular or particulate components in the photoresins. Herein, a simple, affordable, and easily accessible approach for fabricating precise and intricate anisotropic composite materials based on external-module-free anisotropic VP (AVP)-3DP. Preprogrammed force field, i.e., compressional stress in a confined space within a layer to be cured generated during the repetitive descending and ascending motion of a platform for anchoring printed objects in typical VP-3DP processes effectively stack mica flakes within a layer to be cured. While the AVP-3DP of composite resin containing mica flakes with the size of 3 μm, which is sufficiently smaller that the thickness of a layer to be cured, afforded a more isotropic material, those with the sizes down to 10 μm afforded highly anisotropic printed objects, suggesting tunability in anisotropy simply by changing the type of mica flakes. The proposed AVP-3DP methodology leads to anisotropy in the mechanical properties of the 3D-printed object by direction, allowing for up to a 4-fold differentiation for flexural strength and up to a 2-fold differentiation for flexural modulus (E). Moreover, with AVP-3DP of a composite resin containing specific mica flakes, exceptionally high average E of 13.6 GPa has been achieved, which is surprisingly comparable to that of metal lead (E = 13–15 GPa). The ability to create anisotropic composites through AVP-3DP paves the way for the development of next-generation highly precise functional anisotropic objects having intricate geometries with tailored mechanical performance for diverse applications.
Minimally Invasive Mesh Rectopexy versus Perineal Rectosigmoidectomy in the Elderly: A Retrospective Comparative Analysis
Authors: Williams Brian , Gupta Abhinav , Martucci Jordan , Swinford Aubrey , Cologne Kyle G. , Koller Sarah E. , Duldulao Marjun P. , Shin Joongho , Lee Sang W. 
Published: September 2024

Abstract

Aim: The aim of this study was to compare early and intermediate perioperative outcomes after rectal prolapse repair in elderly patients undergoing either minimally invasive mesh rectopexy or perineal rectosigmoidectomy.
Methods: This was a retrospective comparative analysis evaluating outcomes of elderly patients, age ≥ 70 years, undergoing surgical correction of full thickness rectal prolapse at a single tertiary hospital between 2010 – 2023. Patients must have undergone minimally invasive rectopexy or perineal rectosigmoidectomy (Altemeier). Primary outcomes evaluated included 30-day mortality and complication rates.
Results: A total of 55 patients were included, 42 who underwent minimally invasive rectopexy (MIR) and 13 who underwent perineal rectosigmoidectomy (PR). The average age of all patients was 79.8 ± 6.4 years, average body mass index (BMI) was 22.5 ± 3.7, and 49 (89.1%) patients were female.
Patients that underwent MIR had a significantly lower 30-day complication rate compared to PR patients (11.9% vs. 53.8%, respectively; p=0.001). There were 0 (0%) deaths in either group within 30 days of repair.
PR patients had similar recurrence rates to MIR patients with median interval to first documented recurrence of 6.0 (range 0.2-24.5) months. Rate of normal bowel function achieved at most recent follow-up was significantly higher for MIR patients compared to PR (76.2% vs. 30.8%, respectively; p=0.003).
Discussion: MIR approach to prolapse repair is safe and feasible in elderly patients with lower 30-day complication rate and comparable mortality rates compared to patients undergoing PR. Additionally, overall, early functional outcomes were better after MIR.
Cyanobacteria dynamics and Microcystins: an emphasis on late autumn mass development of Woronichinia and Microcystis in the Reservoir Zit-Emba, North-East Algeria
Authors: Guellati Fatma Zohra , Touati Hassen , Seridi Lamia , Djabourabi Aicha , Sehili Nadira , Kadri Skander El-Hadi , Bensouilah Mourad 
Published: September 2024

Abstract

Despite the available studies on Cyanobacteria dynamics, toxicity, and the incriminated environmental variables in the North African freshwater ecosystems, this is still insufficient. This study focuses on the spatiotemporal dynamic of cyanobacteria in the reservoir Zit-Emba and the role of environmental variables. Sampling was carried out from March 2015 to February 2016 at four sampling points (S1-S4). The cooccurrence of two bloom forming cyanobacteria Microcystis and Woronichia and their massive development in autumn (9x104 cells.mL− 1 and 8x104 cells.mL− 1 respectively) was an unexpected phenomenon. Woronichinia is a worldwide poorly studied toxic cyanobacterium reported mainly in Europe and America. Microcystins were detected during the monitoring period (0.04–5.74 µg.L− 1), and peaks were reported during the cyanobacteria bloom. PCA and correlation results revealed the important role of water temperature and nutrient loading mainly P-PO4 (max = 0.4 mg.L− 1) as the most contributing variables. This study highlights the need for regular monitoring of cyanobacteria and their toxins as well as implementing watershed management to reduce nutrient inputs in freshwater sources used for drinking water supplies.
Mechanical Properties and Mechanisms of Concentration-Controlled Alkali-activated Fly Ash Stabilized Saline soil in Seasonally Frozen regions
Authors: Li Sining , Huang Yong , Sun Jian , Cui Qiushuang , Yu Rui , Liu Yubin 
Published: September 2024

Abstract

Sulfate saline soil in the seasonally frozen zone generate soil freeze-thaw cycles, as well as saline expansion and thawing, which causes road engineering issues, thus they should be strengthened. This work investigates the effect of alkali content on the activation of fly ash (FA) stabilized sulfate saline soil by conducting unconfined compressive strength (UCS), splitting strength, and freeze-thaw cycles (FTs) tests. The results demonstrate that as NaOH concentration increases, the UCS and splitting strength tend to increase first, then decrease. N3 (stabilized soil with 0.5 M stimulated FA) had the best performance, with UCS and splitting strength of 7.18 MPa and 1.89 MPa, respectively. The residual values of the UCS and N3 splitting strength after 5 FTs were 46.35% and 39.92%, respectively. The NaOH activated FA hydration products consisted primarily of C-S-H, C-A-H gel and ettringite, with the gels linking the saline soil particles and filled the cracks between them. As a result, the mechanical characteristics and frost resistance of saline soil were much enhanced. The results of the study can provide a reference for the solidification treatment of sulfate saline soil foundations in seasonally frozen regions.
Microservices Adaptability and Self-Organization of UAV-Assisted Wireless Networks in Failure Rural Scenarios
Authors: García-López Andrés , Ramos-Ramos Diego , García-Gil Santiago , Gómez-delaHiz José , Murillo Juan Manuel , Galán-Jiménez Jaime 
Published: September 2024

Abstract

Internet adoption continues to rise every year, with approximately 2 billion people in remote regions lacking connectivity, depriving them of essential services like healthcare and distance education. By leveraging the capabilities of Unmanned Aerial Vehicles (UAVs) network architectures, this paper proposes an energy-efficient solution capable of dynamically adapting the UAV-based network after potential hardware failures or UAV battery depletion. Additionally, integrated with the UAV Controller framework for real-time network management, the combination of adaptability and this technology ensures agility in responding to changing environmental needs. The main objectives include proposing a UAV-based network architecture to deploy Internet of Things (IoT) applications in rural areas and ensuring uninterrupted service provision even in adverse conditions. In this way, IoT applications required by users are provided by the UAV network, improving the quality of life of the rural population. Simulation results over realistic scenarios show a success rate, handling over 90% of the set of requests made by users in different situations.
Allelopathic Effect of (Casimiroa edulis Llaveet Lex.) Leaf Extracts on Germination and Seedling Growth of Maize (Zea mays L) and Sorghum (Sorghum bicolor (L) Moench)
Authors: Worku Sintayehu , Chimdesa Meseret , Yusuf Zekeria 
Published: September 2024

Abstract

The changes over time of both composition and quantity of allelochemicals can either increase or decrease the phytotoxicity of decomposing plant litter. The present study was undertaken to investigate the allelopathic effects of leaf extracts of C. edulis on sorghum and maize seed germinations. The aqueous extract of white sapota (Casimiroa edulis L1ave & Lex) leaf samples were used as a source of allelochemicals. Data collection involved the germination and seedling growth parameters including Germination rate (GR); germination inhibition rate GIR); MGT: mean germination time (MGT); germination index (GI); Relative length of plumule (RLP); germination speed (v); relative length of radicle (RLR); plumule inhibition rate (PIR); radicle inhibition rate (RIR); allelopathic index (AI). The result indicated that highest concentration of the allelopathic extract (20 mg/L) has demonstrated significantly the highest germination inhibition rate (56.67%) for sorghum; GIR (36.67%) and MGT (3.90 days) for maize seeds, while the highest PIR (76.05%) and RIR (89.60%) for sorghum, as PIR (56.79%), RLR (80.09%) for maize seeds. The allelopathic intensity was found to be the highest (50%) for sorghum, and (36.67%) for maize seed germination. For sorghum seed germination, the first principal component (PC1) has got high positive loads from germination rate (0.36), RLP(0.36), AI(0.36), RLR (0.35), and GI (0.31). The PC2 has got the highest positive load (0.67) from germination speed, but high negative load from MGT(-0.68). In allelopathic effect on maize seed germination, PC1 has got highest scores from AI (0.51), and GI (0.51), but highest negative scores from relative length of plumule (-0.51). It can be concluded that the highest negative scores in PCs which is GIR indicate direct relationship between the negative allelopathic index and negative score factors. However, the highest positive scores in PCs indicate positive AI in both sorghum and maize seed germinations.
Construction of DNA replication stress gene related risk model and for prognosis in bladder cancer
Authors: Xie Hao , Guo Jiahao , Yang Yufan , li Yue , Yang Jinshang , Cha Jiazi , Li Xinxin , Niang Ling , Tao Hui ying , Lin Chunhua , Dong Changming 
Published: September 2024

Abstract

Bladder cancer (BLCA) remains a widespread and serious cancer globally. The importance of constructing predictive risk models based on DNA replication stress-related genes (DRSGs) is gaining traction. Despite the scarcity of molecular studies, our analysis of Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets led to the identification of 17 DEDRSGs with prognostic significance, primarily involved in DNA replication and cell cycle control. Subsequently, utilizing LASSO regression, we filtered out nine key biomarkers to develop a risk model that effectively distinguishes immunological profiles and GSVA hallmark pathways across risk strata. Besides, significant differences were observed in the distribution of 191 drugs across the two risk groups. Finally, qRT-PCR was performed to confirmed that BUB1B was significantly highly expressed in 5637 cells line, while the expression level of RAD9A was higher in SV-HUC-1 cell line. In conclusion, the risk model, based on the nine biomarkers, offers a theoretical framework for exploring underlying molecular mechanisms in BLCA.