bluuebunny/crossref_metadata_2025_split huggingface dataset:
Repeated CT scans on 12,984 Asians to diagnose lung cancer once it is suspected
Authors: Vy Vu Pham Thao , Chien Li-Nien , Chen Wan-Ting , Lin Wan-Ying , Chang Yeun-Chung , Hsu Hsian-He , Chan Wing P. 
Published: September 2024

In Taiwan, lung cancer remains the leading cause of cancer-related fatalities, resulting in substantial healthcare expenses. This research aims to evaluate both the frequency and the costs of low-dose computed tomography (LDCT) in individuals suspected of having lung cancer until their diagnosis of cancer. LDCT screening was not conducted on a population-wide scale, and asymptomatic participants had to cover the expenses for the screening personally or reimburse from other sources. If the screening results were positive or suspicious, National Health Insurance (NHI) could be utilized for subsequent follow-up examinations. This cohort study utilized the NHI Database and focused on individuals with suspected cases of lung cancer identified between 2010 and 2014. A total of 17,572 suspected new lung cancer cases were initially identified and assigned to the relevant International Classification of Diseases codes. Individuals with suspected lung cancer received a diagnosis following an average follow-up period of 2.24 (95%CI, 2.11-2.37) years, and required the use of 2.36 (95%CI, 2.20-2.51) repeated CT scans. The NHI expenditures incurred by the use of CT scans for monitoring suspected lung cancer cases were relatively modest.
Testing home-based exercise strategies in underserved minority cancer patients undergoing chemotherapy (THRIVE) trial: a study protocol
Authors: Yan Huimin , Gonzalo-Encabo Paola , Wilson Rebekah L. , Christopher Cami N. , Cannon James D. , Kang Dong-Woo , Gardiner John , Perez Michelle , Norris Mary K. , Gundersen Daniel , Hayman Laura L. , Freedman Rachel A. , Rebbeck Timothy R. , Shi Ling , Dieli-Conwright Christina M. 
Published: September 2024

BackgroundHigher rates of physical inactivity and comorbid conditions are reported in Hispanic/Latinx and Black cancer patients receiving chemotherapy compared to their White counterparts. Despite the beneficial effect of exercise training for cancer patients, rates of participation in exercise oncology clinical trials are low among disadvantaged and racial and ethnic minority groups. Here, we will examine the effect of an exercise intervention using a novel, accessible, and cost-effective home-based exercise approach among Hispanic/Latinx and Black cancer patients receiving chemotherapy on exercise participation and cardiovascular disease risk.MethodsThe THRIVE trial is an 8-month prospective, three-arm study of 45 patients who are randomized in a 1:1:1 fashion to a supervised exercise intervention (SUP), unsupervised exercise (UNSUP), or an attention control (AC) group. Eligible patients include those with breast, colorectal, or prostate cancer, who are sedentary, overweight or obese, self-identify as Hispanic/Latinx or Black, and plan to receive chemotherapy. Patients randomized to the SUP group participate in a home-based 16-week periodized aerobic and resistance exercise program performed three days per week, supervised through video conference technology. Patients randomized to the UNSUP group participate in an unsupervised 16-week, telehealth-based, periodized aerobic and resistance exercise program performed three days per week using the same exercise prescription parameters as the SUP group. Patients randomized to the AC group receive a 16-week home-based stretching program. The primary outcome is changes in minutes of physical activity assessed by 7-day accelerometry at post-intervention. Secondary outcomes include cardiovascular risk factors, patient-reported outcomes, and physical function. Outcome measures are tested at baseline, post-intervention at month 4, and after a non-intervention follow-up period at month 8.DiscussionThe THRIVE trial is the first study to employ a novel and potentially achievable exercise intervention for a minority population receiving chemotherapy. In addition, this study utilizes an intervention approach to investigate the biological and behavioral mechanisms underlying exercise participation in these cancer patients. Results will guide and inform large randomized controlled trials to test the effect of home-based exercise on treatment outcomes and comorbid disease risk in minority patients with cancer undergoing chemotherapy.Clinical trial registrationhttps://classic.clinicaltrials.gov/ct2/show/NCT05327452, identifier (NCT#05327452).
Clinical characteristics of adults with alcohol dependence syndrome comorbid with antisocial personality disorder: a cross-sectional study
Authors: Jarcuskova Dominika , Pallayova Maria , Carnakovic Simona , Frajka Maria , Fidmik Jan , Bednarova Aneta 
Published: September 2024

IntroductionAntisocial Personality Disorder (ASPD) is characterized by a pervasive pattern of disregard for and violation of the rights of others, typically emerging by age 15 years and involving behaviors such as deceitfulness, impulsivity, and aggressiveness. The present study sought to examine the prevalence of the comorbid ASPD in adult people with Alcohol Dependence Syndrome (ADS) and identify clinical characteristics associated with ASPD.MethodsA cross-sectional study of 100 consecutive subjects diagnosed with ADS was conducted. Subjects were examined between August 2023 and September 2023. Various assessments and questionnaires were employed, including the Montreal Cognitive Assessment (MoCA), Alcohol Use Disorders Identification Test (AUDIT), and Structured Clinical Interview for DSM-IV (SCID-II). A computed tomography (CT) scan of the brain was performed on 47.5% participants.ResultsOut of the 100 individuals screened for the study, 20 were excluded. The study found that 35% of the examined study participants had a comorbid ASPD. Individuals with both ADS and ASPD were more likely to be younger, started drinking at an earlier age, had higher hospitalization rates, and scored higher on the AUDIT test (all P &lt; 0.05%). Also, they had lower education levels, higher rates of unemployment, and lower marriage rates (all P &lt; 0.05%). In addition, they reported more family members with ADS, incarceration, or mental illness and a higher frequency of traumatic experiences (all P &lt; 0.05%). Depression, anxiety, stress (all P &lt; 0.05%), and sleep problems (P = 0.058) were correlated with ASPD. Participants with the comorbid ASPD had lower MoCA scores (P = 0.046) and struggled with attention and linguistic subtests compared to subjects with ADS only.ConclusionThe study highlights the high prevalence of comorbid ASPD in participants with ADS, shedding light on their demographic and psychometric characteristics. Individuals with the comorbid ASPD are more likely to face cognitive deficits, especially in linguistic and attention-related tasks. The findings underline the importance of considering the comorbidity of ASPD in ADS subjects. The study implies that the understanding of the associated risk factors can aid in developing more targeted treatment interventions.
Economic evaluation of the prevention of falls resulting from missed care in polish hospitals
Authors: Wieczorek-Wójcik Beata , Gaworska-Krzemińska Aleksandra , Owczarek Aleksander Jerzy , Kilańska Dorota 
Published: September 2024

ObjectivesFalls are associated with increased morbidity, mortality, prolonged hospitalization and an increase in the cost of treatment in hospitals. They contribute to the deterioration of fitness and quality of life, especially among older patients, thus posing a serious social and economic problem. They increase the risk of premature death. Falls are adverse, costly, and potentially preventable. The aim of the study was to analyze the cost-effectiveness of avoiding one fall by nurse care provided by the nurses with higher education, from the perspective of the health service provider.MethodsThe economic analysis included and compared only the cost of nurse intervention measured by the hours of care provided with higher education in non-surgical departments (40.5%) with higher time spend by nurses with higher education level an increase in the number of hours by 10% (50.5%) to avoid one fall. The time horizon for the study is 1 year (2021). Cost-effectiveness and Cost–benefit analysis were performed. All registered falls of all hospitalized patients were included in the study.ResultsIn the analyzed was based on the case control study where, 7,305 patients were hospitalized, which amounted to 41,762 patient care days. Care was provided by 100 nurses, including 40 nurses with bachelor’s degrees and nurses with Master of Science in Nursing. Increasing the hours number of high-educated nurses care by 10% in non-surgical departments decreased the chance for falls by 9%; however, this dependence was statistically insignificant (OR = 1.09; 95% CI: 0.72–1.65; p = 0.65). After the intervention (a 10% increase in Bachelor’s Degrees/Master of Science in Nursing hours), the number of additional Bachelor’s Degrees/Master of Science hours was 6100.5, and the cost was USD 7630.4. The intervention eliminated four falls. The cost of preventing one fall is CER = USD 1697.1.ConclusionThe results of these studies broaden the understanding of the relationship among nursing education, falls, and the economic outcomes of hospital care. According to the authors, the proposed intervention has an economic justification.
Habitat Suitability Modeling of Endemic Genus Chimonanthus in China under Climate Change
Authors: Su Qitao , Du Zhixuan , Xue Yuxi , Li Heng , Zhang Yuxin , Zhang Shujian , Huang Xinyi , Zhou Bing , Qian Hao , Xiao Yi’an , Zou Zhengrong 
Published: September 2024

Climate change has significantly altered in the distribution of plant and animal species, potentially resulting in either species expansion or extinction. The genus Chimonanthus, an economically significant and endemic group in China, holds substantial medicinal and ornamental value; however, its wild resources are limited. There is a paucity of knowledge regarding the distribution characteristics of the genus Chimonanthus species and the critical ecological factors influencing habitat suitability. Utilizing species distribution data and environmental variables, we performed simulations and analyses to identify suitable habitats, evaluate the primary environmental factors influencing distribution, determine potential distribution areas and centroids, and predict changes in suitable areas under three future climate scenarios (SSP-126, SSP-245, SSP-585) employing MaxEnt and ArcGIS. These findings indicated that the Area Under Curve (AUC) values exceeded 0.97 for all five Chimonanthus species, suggesting that the model predictions are highly accurate. The primary environmental variables influencing the distribution of C. grammatus are temperature, particularly isothermality (BIO3), and the mean temperature of warmest quarter (BIO10). However, precipitation of warmest quarter (BIO18) was an important environmental factor limiting the distributions of C. praecox, C. nitens, C. salicifolius and C. zhejiangensis. In the current period, the area of habitat suitability for C. praecox is the largest, at 2,498,600 km2, while that for C. zhejiangensis is the smallest, at 700,400 km2. The five Chimonanthus species are distributed mainly in southern China under the current climate scenario and will migrate to higher latitudes under future climate scenarios. C. nitens had high niche overlap and range overlap with C. zhejiangensis and C. salicifolius, respectively. A similar situation occurs between C. zhejiangensis and C. salicifolius. These findings suggest that there may be strong interspecific competition among adjacent species. Our results indicate that the establishment of nature reserves at current distribution sites within optimal areas is crucial for the conservation of germplasm resources, particularly for C. grammatus and C. salicifolius. The data generated from this research can serve as a valuable reference for the selection of in situ conservation sites, the determination of appropriate planting locations, the scientific introduction of species, and the development of long-term conservation and management strategies for Chimonanthus.
A Single-Center Retrospective Study to Identify Causes of Sex Differences in the Living Kidney Donor Evaluation Process
Authors: Chumdermpadetsuk Ritah R. , Montalvan Adriana , Canizares Stalin , Chopra Bhavna , Pavlakis Martha , Lee David D. , Eckhoff Devin E. 
Published: September 2024

Key Points

Female overrepresentation in living kidney donation stems from higher self-referral rates, not differences in approval or follow-through.Male volunteers are not more likely to be declined as donors due to medical contraindications, contrary to common assumptions.Engaging more male volunteers in living donation could expand access to kidney transplantation and reduce waitlist times.

Background
Multiple studies have shown that female volunteers are living donors (LDs) for kidney transplantation at higher rates than male volunteers. However, the underlying reasons for this observation are not well understood. We examined the LD evaluation process to determine the point at which sex imbalance arises. On the basis of a previous study, we hypothesized that both sexes are equally likely to become approved as LDs, but female volunteers are more likely to follow through with donation.

Methods
This is a single-institution retrospective chart review of self-referrals for LD evaluation between January 2009 and December 2022. Self-referrals were identified using the Organ Transplant Tracking Record database and cross-referenced with billing data. Exclusion at each stage of evaluation was recorded and compared between sexes using log binomial regression; unadjusted and adjusted (for donor age, race, ethnicity, relationship to recipient, and recipient sex) risk ratios with 95% confidence interval were determined.

Results
One thousand eight hundred sixty-one self-referrals were reviewed, including 1214 female (65.2%) and 647 male (34.8%) volunteers, resulting in 146 approvals and 125 donations (76/125, 60.8% female, 49/125, 39.2% male). Adjusted risk ratios indicated no significant differences between sexes in completing medical and/or psychosocial workup, having medical and/or psychosocial contraindications, being approved for donation, and proceeding with donation. The top medical contraindications for both sexes were obesity, hypertension, and nephrolithiasis.

Conclusions
Female overrepresentation among LDs is likely due to the 1.9 times higher rate of self-referral for evaluation. After this point, both sexes were equally likely to complete workup, be approved, and follow through with donation. Increased efforts to engage male volunteers at the initial self-referral stage has the potential to expand access to LD kidney transplantation.

Podcast
This article contains a podcast at https://dts.podtrac.com/redirect.mp3/www.asn-online.org/media/podcast/K360/2024_12_26_KID0000000581.mp3
Design foundations for traditional interior spaces (Local reception halls are an example)
Authors: Hashim Wisam hassan 
Published: September 2024

تتسم الفضاءات الداخلية التقليدية في العمارة العربية والإسلامية بطابعها الفريد الذي يعكس الثقافة والتراث المحلي,وتشمل مجموعة واسعة من الأماكن داخل المنازل والمباني التقليدية, وتعد صالات الضيوف التقليدية التي تعرف أيضًا بالمضايف في العراق والمجالس أو الديوانيات في بعض الدول العربية من اهمها ، وهي أماكن مخصصة لاستقبال الضيوف وتجمعات الأهل والأصدقاء، وتعكس جانباً من الضيافة العربية الأصيلة, والتقاليد المحلية وتتنوع تصاميم هذه الصالات وأساليبها باختلاف الثقافات والتقاليد المحلية, يتكون البحث الحالي من اطارا منهجيا يتكون من مشكلته تتمثل بالتساؤل التالي: ما مدى فاعلية العوامل الثقافية والاجتماعية في تصميم الفضاءات الداخلية للمضايف المحلية؟ و هدف البحث الحالي الى : الكشف عن واقع حال تصاميم فضاءات الاستقبال التقليدية ومرجعيات تصميمها , وايجاد مرتكزات تصميمية لفضاءات الاستقبال التقليدية بما يسهم في تعزيز الاحساس بالتناغم الاجتماعي بين تلك الفضاءات وخصوصية روادها.واطارا نظريا يتكون من مبحثين الاول : الثقافة المحلية وانعكاساتها في التصميم الداخلي المبحث الثاني: تصميم الفضاءا الداخلية لغرف الاستقبال المحلية. واجراءات بحثه الذي انتهج بها المنهج الوصفي وتوصل البحث على نتائج: اذ وقام الباحث بالتحليل وفق الاستمارة التي اعدها سلفا وتوصل الى النتائج المثبتة احصائيا الوسط الحسابي لفقرات الاستمارة 3.27ونسبة مئوية معدل جميع الفقرات 81.9% ,واستنتاجات همها:
الوعي الذاتي في الفلسفة العدمية لتأويل التجربة الجمالية(النحات البرتو جاكوميتي إنموذجاً)
Authors: جمعة زبون البهادلي احمد , عيدان علي فاهم 
Published: September 2024

يسلط البحث الضوء على مخرجات تأثر الوعي الذاتي للفنان بالفلسفة العدمية لتأويل التجربة الجمالية، متخذاً النحات البرتو جياكومتي أنموذجا، وتوزع البحث على عدة فصول حيث كان الفصل الأول المنهجي إذ قدمت فيه لمشكلة البحث التي ختمتها بالسؤال: ما أهمية الوعي الذاتي في تأويل التجربة الجمالية تحت تأثير الفلسفة العدمية؟ ولخصت أهمية البحث في تقصي أثر الفلسفة العدمية وأثرها في الوعي الذاتي لتأويل التجربة الجمالية، وكان هدف البحث التعرف على أثر الفلسفة العدمية في الوعي الذاتي لتأويل التجربة الجمالية، وكانت حدود البحث في الحد الموضوعي تأثير الفلسفة العدمية في التجربة الجمالية للنحات البرت جاكومتي، الحد المكاني: فرنسا، الحد الزماني : 1932-1961، وقمت بتحديد أهم المصطلحات في البحث زهي مصطلحي الذاتية والعدمية، أما الفصل الثاني ضمن الاطار النظري فقسمته الى ثلاث مباحث، المبحث الاول: رؤية عامة حول مفهومي الذاتية والعدمية، والمبحث الثاني: المفاهيم الجمالية للفلاسفة العدميين.وفيه تناولت اراء أربعة فلاسفة عدميين في الفن والجمال من رؤية عدمية هم (نيتشة، سورين كيكغارد ،هايدجروبول سارتر)، والمبحث الثالث: التجربة الجمالية وتأويلها عدمياً. من خلال دراسة أهم المدارس الفنية الحداثوية التي تأثرت بالفلسفة العدمية وأستعراض نتاجها في التجربة الجمالية، وفي الفصل الثالث ضمن الإطار الإجرائي للبحث وفيه تناولت منهج البحث ومجتمع البحث وأداة البحث وعينة البحث التي تناولت فيها أربعة أعمال للفنان البرتو جياكومتي، ومن ثم قمت بتحليل العينة من خلال النماذج المختارة للتحليل، أما الفصل الرابع الذي استخلصت فيه النتائج، التي كان أبرزها الفنان في أدائه الفني هو باحث عن الحقيقة الجمالية المحسوسة والمشفرة وراء ظواهر وتجليات العمل الفني. أختزال الشكل الفني وتقشيره هو لإظهار جوهره وإنكشاف وتجلي حقيقة وجوده. خيال الفنان يغوص في ذات الشكل الجمالي لينسج شكلاً جديداً مركباً من ذات الفنان مع التشكل الظاهري للموجودات الخارجية. من خلال الاختزال عمم الفنان رؤيته العدمية في المنجز الشكلي الانساني والتبسيط والأسبلة. ومن ثم ثبت المصادر.
Design dialogue is a cognitive accompaniment in the designs of interior spaces(As a case study of the hospitality hall in Qasr Al Watan - Abu Dhabi (UAE)
Authors: Jarallah Tawfik Mohamed 
Published: September 2024

ان الحوار التصميمي لا يقتصر على عرض الأفكار القديمة التي يؤمن المصمم الداخلي بها وإنما يرتكز على طريقة بنائية الأفكار التي تتكون في ذهنه، و هذا يعتمد إلى توضيح المعاني المتولدة من خلال عرض الفكرة ,فضلاً عن تأطيرها وتقديمها بأسلوب علمي مقـنع للطرف الآخر، بحيث يظل العقل واعياً طوال فترة المحاورة ليستطيع إصدار الحكم عليها، وبذلك فأن الحوار التصميمي يمثل أداة أسلوبية تستخدم لمعالجة موضوع من الموضوعات المتخصصة لاسيما في حقل من حقول العلم والمعرفة التصميمية, بل وتمثل جانب من جوانب الفكر التصميمي, وهذا يعتمد على الدور الفعال لرؤية المصمم الداخلي المبنية على أساس اختيار الإطار الفكري المحدد ضمن رؤيا فكرية عقلانية تصميمية محدده لحقيقة ذاتية الشيء للوصول الى النتاج التصميمي المطلوب تنفيذه وعلى الدور المحفز المنبثق من تفاعله مع المكان ,لذلك كان لابد من دراسة هذا الموضوع المتكون من أربعة فصول, فبالنسبة للفصل الاول أعتمد الباحث على صياغة مشكلة البحث التي تتلخص بالتساؤل الاتي: ماهي الاعتبارات التي يعتمدها الحوار التصميمي كمواكبة معرفية في تصاميم الفضاءات الداخلية لصالة الضيافة في قصر الوطن - أبوظبي (الامارات) ؟في حين تكمن أهمية البحث في تحقيق وظيفة اتصالية بين المصمم الداخلي والمتلقي من خلال المخاطبة الذهنية التصميمية التي تحمل ابعاداً معرفية بحيث تثير لدى المتلقي معاني حوار ضمنية قابلة للإدراك الحسي, وعلى ضوء ذلك ركز الباحث هدف البحث في التوصل الى معرفة أهم الاعتبارات التي يعتمدها الحوار التصميمي كمواكبة معرفية في تصاميم الفضاءات الداخلية لصالة الضيافة في قصر الوطن -أبوظبي (الامارات)، أما بالنسبة لحدود البحث فقد ’حدد الباحث من ناحية الحد الموضوعي ب(الحوار التصميمي مواكبة معرفية في تصاميم الفضاءات الداخلية (كدراسة حالة لصالة الضيافة في قصر الوطن - أبوظبي (الامارات) ,في حين تضمن حدوده المكانية والزمانية الفضاءات الداخلية الحديثة والمتمثلة صالة الضيافة في قصر الوطن - أبوظبي (الامارات) المنفذة في العام 2019م,بينما أعتمد الفصل الثاني الى دراسة أولاً: اعتبارات الحوار التصميمي وثانياً اعتبارات المواكبة معرفية , بينما تضمن الفصل الثالث في تحديد موضوع اجراءات البحث والمتمثلة بمنهجية البحث المعتمدة على المنهج الوصفي التحليلي بينما تركز مجتمع البحث الى اعتماد أسلوب الانتقائي القصدي واخيراً تضمن الفصل الرابع استخلاص نتائج البحث .
Pelatihan Eco-Enzyme untuk Pencegahan Blooming Eceng Gondok di Sungai Bengawan Solo
Authors: Farahdiansari Ardana Putri , Rahmawati Laily Agustina , Rendra Mrabawani Insan , Tohir Muhammad Bakhru , Rosyadin Aulia Dinar 
Published: September 2024

Sungai Bengawan Solo memiliki peran besar dan penting dalam kehidupan masyarakat di alirannya mulai dari Jawa Tengah sampai Jawa Timur. Namun ternyata kegiatan masyarakat seringkali menimbulkan dampak terhadap Bengawan Solo terutama terkait polusi dan kerusakan lingkungan. Salah satu fenomena yang mengkhawatirkan adalah blooming Eceng Gondok, yang terjadi akibat kemarau panjang sehingga menyebabkan tingginya konsentrasi limbah organik di perairan sungai pada akhir tahun 2023. Meningkatnya kegiatan manusia termasuk salah satunya kegiatan rumah tangga menyebabkan semakin tingginya jumlah limbah yang dihasilkan dari waktu ke waktu. Banyaknya limbah yang masuk ke sungai ini tentu menimbulkan peningkatan unsur hara sungai sehingga menyuburkan Eceng Gondok sepanjang Bengawan Solo termasuk di area desa Kuncen, kecamatan Padangan. Agar limbah rumah tangga tidak menimbulkan permasalahan untuk lingkungan dan kesehatan, maka perlu dilakukan pengolahan lebih lanjut terkait limbah tersebut. Jenis limbah rumah tangga salah satunya yaitu sisa sayuran dapat menjadi sumber bahan baku alternatif untuk dijadikan produk eco-enzyme. LPPM Universitas Bojonegoro bekerja sama dengan Jasa Tirta I melakukan kegiatan pendampingan masyarakat dengan memberikan edukasi serta mengampanyekan kesadaran akan pentingnya menjaga kondisi lingkungan sungai Bengawan Solo. Edukasi dan kampanye tersebut juga ditujukan untuk meminimalisir limbah dari rumah tangga terutama sampah organik sehingga tidak terjadi penumpukan unsur hara penyebab blooming enceng gondok. Dengan pelaksanaan pengabdian masyarakat ini, maka didapatkan bahwa wawasan ibu rumah tangga untuk pengelolaan limbah rumah tangga terutama sisa sayuran menjadi bertambah, sehingga limbah tersebut dapat dikelola menjadi eco enzyme yang bermanfaat untuk lingkungan.