bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reinerantha foliicola, a new genus and species of Lejeuneaceae subtribe Cololejeuneinae (Marchantiophyta) from Ecuador
Authors: Gradstein S. Robbert , Zhu Rui‐Liang , Shu Lei , Pérez Álvaro J. 
Published: November 2017

AbstractCololejeuneinae is the largest subtribe of the liverwort family Lejeuneaceae and the crown group of the family. The species often grow on the surfaces of living leaves and twigs or in swiftly running waters and many of them possess neotenic gametophytes, considered an adaptation to these extreme habitats. We describe a new, epiphyllous genus and species in Cololejeuneinae from the Western Cordillera of Ecuador, Reinerantha foliicola Gradst. & R.L.Zhu. Analysis of combined molecular datasets with parsimony, maximum likelihood and Bayesian methods revealed Reinerantha in a sister relationship to the large pantropical genus Diplasiolejeunea. Reinerantha differs from Diplasiolejeunea in leaf segmentation, epidermal wall thickening, stylus, male bracts and perianth keels, and is morphologically more similar to the genus Tuyamaella. In the molecular analysis, however, Reinerantha and Tuyamaella were resolved in different clades and not closely related. Tuyamaella is shown to be restricted to Asia; the report of Tuyamaella from South America (Peru) was erroneous and a case of mislabeling.
Epidural abscess caused by Schizophyllum commune: A rare case of rhinogenic cranial complication by a filamentous basidiomycete
Authors: Tone Kazuya , Fujisaki Ryuichi , Hagiwara Shigehiro , Tamura Takashi , Ishigaki Shinobu , Alshahni Mohamed Mahdi , Takehisa Makoto , Watanabe Takehiro , Yasui Takuya , Tokairin Takuo , Sagawa Toshiyo , Sakamoto Tetsuya , Ito Ken , Kuwano Kazuyoshi , Makimura Koichi 
Published: November 2017

SummaryCentral nervous system (CNS) infections due to filamentous basidiomycetes are extremely rare. We encountered a case of epidural abscess due to Schizophyllum commune that extended from sinusitis. A 53‐year‐old Japanese man presented at our hospital with a headache. Computed tomography (CT) of the cranium and sinuses showed ethmoid and sphenoid sinusitis with no intracranial abnormalities. The patient was diagnosed with acute sinusitis and underwent antibiotic treatment. However, the symptoms deteriorated, and the patient came to our hospital again with consciousness disturbance. CT scan of the cranium and sinuses showed no improvement of sinusitis after antibiotic therapy and an epidural abscess emerged in the middle cranial fossa. Therefore, emergency craniotomy and endoscopic sinus fenestration were performed. Filamentous fungal elements were observed in both rhinorrhoea and epidural abscess. The symptoms improved after the operation and administration of liposomal amphotericin B. The clinical isolate was identified as S. commune by a molecular‐based method. To our knowledge, this is the first report of epidural abscess due to this fungus. Although rare, clinicians should be aware that S. commune could be a causative agent of CNS infections.
Workplace delivery of a dietitian‐led cardiovascular disease and type 2 diabetes prevention programme: A qualitative study of participants’ experiences in the context of Basic Needs Theory
Authors: Di Battista E. M. , Bracken R. M. , Stephens J. W. , Rice S. , Thomas M. , Williams S. P. , Mellalieu S. D. ,   the Prosiect Sir Gâr Group
Published: November 2017

AbstractThe Medical Research Council recommends strong theoretical underpinning in the design and evaluation of lifestyle intervention programmes (LIPs). This qualitative study aimed to use Basic Needs Theory (BNT) as a framework to explore participants’ perspectives on a workplace dietitian‐led LIP. Specifically, experiences with LIP engagement and initiation and maintenance of behaviour change were evaluated. Fifteen semi‐structured face‐to‐face interviews were conducted with participants who had previously completed a workplace cardiovascular disease and type 2 diabetes prevention programme, which involved advice and motivational support with making dietary and lifestyle changes. Interviews were audio recorded and transcribed verbatim. To evaluate the narrative, interpretative phenomenological analyses were used with BNT as the theoretical framework. A total of 12 themes were identified in relation to the three concepts of BNT – autonomy, competence and relatedness – and organised into three domains: intervention engagement, behaviour change initiation and behaviour change maintenance. Line manager and colleague support to attend was reported to have a strong influence on intervention engagement, and the importance of dietitian and peer guidance in initiating behaviour changes was highlighted. Differences between participants who maintained behavioural changes compared to those who relapsed included autonomously seeking support (relatedness) through family, friends, healthcare professionals and commercial slimming organisations. BNT provided an insightful theoretical framework to evaluate factors that underpinned the effectiveness of a dietitian‐led cardiovascular and type 2 diabetes prevention LIP. Attendance and retention in workplace LIPs can depend on participants’ managerial and colleague support, so recruitment processes should consider targeting managers in marketing and promotional activities. Workplace LIPs may increase the likelihood of behaviour change maintenance by including methods that foster longer term participant relatedness and emotional support.
The impact of sociodemography, diet, and body size on serum retinol in women 16–35 years of age: SANHANES‐1
Authors: Parker Whadi‐ah , Mchiza Zandile J. , Sewpaul Ronel , Job Nophiwe , Chola Lumbwe , Sithole Moses , Labadarios Demetre 
Published: November 2017

AbstractTo determine the current vitamin A status of a nationally representative sample of women aged 16–35 years, compare it with previous national data, and determine the impact of sociodemography, diet, and body size on vitamin A status, we performed secondary analysis of data on South African women who participated in the first South African National Health and Nutrition Examination Survey (SANHANES‐1). Vitamin A status was assessed by serum retinol, and the findings are reported as means and prevalences with corresponding 95% confidence intervals. Overall, the age‐standardized vitamin A deficiency prevalence was 11.7%, a decrease from previous national data, but serum retinol levels remained lower than in other developing countries. Overall, unweighted, multilevel, multivariate logistic regression showed that vitamin A deficiency was influenced by race only (odds ratio (OR) = 1.89, P = 0.031), while weighted multiple logistic regression for 16‐ to 18‐year‐olds showed that vitamin A deficiency was influenced by locality (OR = 9.83, P = 0.005) and household income (intermediate (OR = 0.2, P = 0.022) and upper (OR = 0.25, P = 0.049)). Despite the decreased prevalence, vitamin A deficiency remains a moderate public health problem in the country. Opportunities for targeted interventions have been identified.
Circulating microRNAs as potential biomarkers in myasthenia gravis patients
Authors: Punga Anna Rostedt , Punga Tanel 
Published: November 2017

AbstractMicroRNAs (miRNAs) are small noncoding RNA molecules that bind to specific mRNA targets and regulate a wide range of important biological processes within cells. Circulating miRNAs are released into the extracellular space and can be measured in most biofluids, including blood serum and plasma. Recently, circulating miRNAs have emerged as easily accessible markers in various body fluids with different profiles and quantities specific for different human disorders, including autoimmune diseases. In myasthenia gravis (MG), diagnostic tests such as titers of serum autoantibodies specific for either the acetylcholine receptor (AChR+) or muscle‐specific tyrosine kinase (MuSK+) do not necessarily reflect disease progression, and there is a great need for reliable objective biomarkers to monitor the disease course and therapeutic response. Recent studies in AChR+ MG revealed elevated levels of the immuno‐miRNAs miR‐150‐5p and miR‐21‐5p. Of particular importance, levels of miR‐150‐5p were lower in immunosuppressed patients and in patients with clinical improvement following thymectomy. In MuSK+ MG, another profile of circulating miRNAs was found, including upregulation of the let‐7 family of miRNAs. Here, we summarize the potential role of circulating miRNAs as biomarkers in general and in MG, and highlight important considerations for the analysis of circulating miRNA.
Oleoylethanolamide: The role of a bioactive lipid amide in modulating eating behaviour
Authors: Sihag J. , Jones P. J. H. 
Published: November 2017

SummaryFatty acid ethanolamides are lipid mediators that regulate a plethora of physiological functions. One such bioactive lipid mediator, oleoylethanolamide (OEA), is a potent agonist of the peroxisome proliferator‐activated receptor‐alpha (PPAR‐α), which modulates increased expression of the fatty acid translocase CD36 that enables the regulation of feeding behaviour. Consumption of dietary fat rich in oleic acid activates taste receptors in the gut activating specific enzymes that lead to the formation of OEA. OEA further combines with PPAR‐α to enable fat oxidation in the liver, resulting in enhanced energy production. Evidence suggests that sustained ingestion of a high‐fat diet abolishes the anorexic signal of OEA. Additionally, malfunction of the enterocyte that transforms oleic acid produced during fat digestion into OEA might be responsible for reduced satiety and hyperphagia, resulting in overweight and obesity. Thus, OEA anorectic signalling may be an essential element of the physiology and metabolic system regulating dietary fat intake and obesity. The evidence reviewed in this article indicates that intake of oleic acid, and thereby the resulting OEA imparting anorexic properties, is dependent on CD36, PPAR‐α, enterocyte fat sensory receptors, histamine, oxytocin and dopamine; leading to increased fat oxidation and enhanced energy expenditure to induce satiety and increase feeding latency; and that a disruption in any of these systems will cease/curb fat‐induced satiety.
Respiration of thermogenic inflorescences of skunk cabbage Symplocarpus renifolius in heliox
Authors: Seymour Roger S. , Ito Kikukatsu , Umekawa Yui 
Published: November 2017

AbstractThe respiration rate of the thermogenic inflorescences of Japanese skunk cabbage Symplocarpus renifolius can reach 300 nmol s−1 g−1, which is sufficient to raise spadix temperature (Ts) up to 15 °C above ambient air temperature (Ta). Respiration rate is inversely related to Ta, such that the Ts achieves a degree of independence from Ta, an effect known as temperature regulation. Here, we measure oxygen consumption rate (Ṁo2) in air (21% O2 in mainly N2) and in heliox (21% O2 in He) to investigate the diffusive conductance of the network of gas‐filled spaces and the thermoregulatory response. When Ts was clamped at 15 °C, the temperature that produces maximal Ṁo2 in this species, exposure to high diffusivity heliox increased mean Ṁo2 significantly from 137 ± 17 to 202 ± 43 nmol s−1 g−1 FW, indicating that respiration in air is normally limited by diffusion in the gas phase and some mitochondria are unsaturated. When Ta was clamped at 15 °C and Ts was allowed to vary, exposure to heliox reduced Ts 1 °C and increased Ṁo2 significantly from 116 ± 10 to 137 ± 19 nmol s−1 g−1, indicating that enhanced heat loss by conduction and convection can elicit the thermoregulatory response.
Changes in nitric oxide levels and their relationship with callose deposition during the interaction between soybean and Soybean mosaic virus
Authors: Xiao D. , Duan X. , Zhang M. , Sun T. , Sun X. , Li F. , Liu N. , Zhang J. , Hou C. , Wang D. 
Published: November 2017

Abstract

The present study aimed to investigate changes in nitric oxide (NO) level and its relationship with callose deposition during the interaction between soybean and Soybean mosaic virus (SMV).

Soybean cv. ‘Jidou 7’ and SMV strains N3 and SC‐8 were used to constitute incompatible and compatible combinations. Intracellular NO was labelled with the NO‐specific fluorescence probe DAF‐FM DA. Confocal laser scanning microscopy (CLSM) was then used to observe changes in NO production during SMV infection‐induced defence responses in soybean.

The results showed NO fluorescence increased rapidly at 2–72 h post‐inoculation, peaked at 72 h and then decreased in the incompatible combination. However, in the compatible combination, extremely weak NO fluorescence appeared in the early stage (2–24 h) post‐inoculation, but was not observed thereafter. Injections of the NO scavenger c‐PTIO prior to inoculation postponed the onset of NO production to 48 or 72 h post‐inoculation. The same occurred when injections of NR or NOS inhibitors were applied prior to inoculation. The observation of callose fluorescence in the incompatible combination revealed that either the elimination or reduction of NO in the early stage led to a delay in callose formation, enabling the virus to cause systemic infection.

Together with our previous findings, this study indicates that viral infection could induce NO production and callose deposition during the incompatible interaction between soybean and SMV. The production of NO involves NR and NOS enzymatic pathways, and NO mediates the process of callose deposition at plasmodesmata.
Dealing with dissonance: A review of cognitive dissonance reduction
Authors: McGrath April 
Published: November 2017

AbstractThis article provides an overview of research about cognitive dissonance reduction. Over the past 60 years, researchers have produced significant theoretical and empirical contributions from cognitive dissonance theory. One of the challenges that remains for dissonance theory going forward is a deeper examination of the process of dissonance reduction. I describe the various reduction strategies that have been investigated followed by models that have been proposed to understand an individual's use of dissonance reduction strategies. I then highlight a series of factors that can help us move research about dissonance reduction forward. These factors can be broadly subsumed under characteristics of the reduction mode and characteristics of the dissonance arousal. I conclude by suggesting that examination of these factors in studies that present multiple reduction modes to participants will provide a better understanding of the process of dissonance reduction.
Use of a hepatitis C virus (HCV) RNA‐positive donor in a treated HCV RNA‐negative liver transplant recipient
Authors: Campos‐Varela Isabel , Agudelo Eliana Z. , Sarkar Monika , Roberts John P. , Terrault Norah A. 
Published: November 2017

AbstractThe shortage of livers has led most transplant centers to use extended criteria donors. Hepatitis C virus (HCV) RNA‐positive donor organs are typically not given to patients who have cleared HCV. A 64‐year‐old male with chronic hepatitis C, genotype 1b was listed for LT with hepatocellular carcinoma. While on the waiting list, the patient was treated with sofosbuvir, ledipasvir, and ribavirin and achieved an HCV RNA <15 IU/mL by week 10. At week 18 of a planned 24‐week treatment course, the patient underwent deceased‐donor LT and received an organ from an anti‐HCV‐positive donor. Treatment was stopped at LT. At week 3 post LT, HCV RNA was detectable and revealed a genotype 3 HCV infection, compatible with transplantation of an organ with established infection. With retreatment with sofosbuvir, daclatasvir, and ribavirin for 12 weeks, the patient achieved a sustained virologic response. This report highlights how antiviral therapies can be used to optimize the outcomes of HCV‐infected transplant patients.
Validation of an updated Associative Transcriptomics platform for the polyploid crop species Brassica napus by dissection of the genetic architecture of erucic acid and tocopherol isoform variation in seeds
Authors: Havlickova Lenka , He Zhesi , Wang Lihong , Langer Swen , Harper Andrea L. , Kaur Harjeevan , Broadley Martin R. , Gegas Vasilis , Bancroft Ian 
Published: November 2017

SummaryAn updated platform was developed to underpin association genetics studies in the polyploid crop species Brassica napus (oilseed rape). Based on 1.92 × 1012 bases of leaf mRNAseq data, functional genotypes, comprising 355 536 single‐nucleotide polymorphism markers and transcript abundance were scored across a genetic diversity panel of 383 accessions using a transcriptome reference comprising 116 098 ordered coding DNA sequence (CDS) gene models. The use of the platform for Associative Transcriptomics was first tested by analysing the genetic architecture of variation in seed erucic acid content, as high‐erucic rapeseed oil is highly valued for a variety of applications in industry. Known loci were identified, along with a previously undetected minor‐effect locus. The platform was then used to analyse variation for the relative proportions of tocopherol (vitamin E) forms in seeds, and the validity of the most significant markers was assessed using a take‐one‐out approach. Furthermore, the analysis implicated expression variation of the gene Bo2g050970.1, an orthologue of VTE4 (which encodes a γ‐tocopherol methyl transferase converting γ‐tocopherol into α‐tocopherol) associated with the observed trait variation. The establishment of the first full‐scale Associative Transcriptomics platform for B. napus enables rapid progress to be made towards an understanding of the genetic architecture of trait variation in this important species, and provides an exemplar for other crops.
Direct costs of transfusion reactions – an expert judgement approach
Authors: Janssen M. P. , van Tilborgh A. J. W. , de Vooght K. M. K. , Bokhorst A. G. , Wiersum‐Osselton J. C. 
Published: November 2017

Background and ObjectivesDespite increasingly meticulous haemovigilance reporting throughout the world, a systematic assessment of the cost of transfusion reactions is still lacking. This is partly caused by the fact that such an assessment requires a subjective expert assessment of the additional costs linked to the adverse reaction. Data on the cost of transfusion reactions could support decision‐making regarding blood transfusion safety measures.Materials and MethodsThirteen experts from nine hospitals were asked to estimate the additional care required following various types of transfusion reactions. Additional care was quantified as the proportion of reactions requiring care, and the amount of care required (e.g. hospitalization days, additional physician's time). Experts were also asked to provide, per type of transfusion reaction, an estimate of the proportion of transfusion reactions preventable. Structured quantitative expert elicitation methods were applied to obtain and combine expert estimates.ResultsThe estimated annual in‐hospital cost of transfusion reactions in the Netherlands is €933 356 per year (€1.52 per transfusion). Two‐thirds (64%) of these are incurred by non‐serious transfusion reactions. Circulatory overload, TRALI and anaphylaxis clearly dominate the costs of serious adverse transfusion reactions (66% in total); non‐haemolytic transfusion reactions incur 46% of the cost of non‐serious transfusion reactions. Additional safety measures targeting circulatory overload and new antibody formation potentially offer the highest cost reduction.ConclusionIn‐hospital costs of transfusion reactions are substantial but contribute to less than 1% of the total cost of transfusion in the Netherlands. A considerable part of these costs (24%) might be preventable.
Critical conversations: Social workers’ perceptions of the use of a closed Facebook group as a participatory professional space
Authors: Stanfield Deb , Beddoe Liz , Ballantyne Neil , Lowe Simon , Renata Nicole 
Published: November 2017

INTRODUCTION: The rise of social media has been associated with rapid growth in different forms of digital networking, debate and activism. Many studies have traced the role of social media in mobilising people to take action on shared issues of concern across the world. Yet, while networked public spaces offer many possibilities for professional engagement and interaction, the technology also shapes social dynamics, raising questions over professional boundaries and the nature of online behaviour.METHOD: The development of a closed professional group on the social networking site, Facebook, provided an ideal opportunity to explore social workers’ perceptions of participatory public space for professional deliberation and debate about public issues. Using a small-scale, case-study approach, group members were invited to complete an online survey and to participate in an interview which explored participants’ motivation for joining the group, the frequency and nature of their contributions, how it felt to be a member and what they valued or found problematic about the group.FINDINGS: Those group members benefitted from the resources, research and professional development opportunities afforded to them and supported the professional potential and promise of social networking sites. They grappled with what constitutes ethical online behaviour and identified the site’s limitations and strengths as a place to promote robust professional dialogue on social issues. IMPLICATIONS: Analysis of social workers’ experience within participatory public spaces offers insight into how the profession can develop modern communication strategies and strong communities of practice in line with its professional principles and mandate.
Genome Sequences of Mycobacteriophages Findley, Hurricane, and TBond007
Authors: Saha Sanghamitra , Yan Wenbo , Washington Jacqueline M. , Davis William B. , Barbazuk W. Brad , Medellin Rosa , Mendez Aissa , Ramos Jacqueline R. , Sadana Rachna , Edmonds Miranda , Feng Guanqiao , Ilyas Maria , Kaiser Joshua , Monroe Stephen J. , Pham Thinh V. , Cresawn Steven G. , Garlena Rebecca A. , Stoner Ty H. , Russell Daniel A. , Pope Welkin H. , Jacobs-Sera Deborah , Hatfull Graham F. 
Published: November 2017

ABSTRACT

We report here the genome sequences of three newly isolated phages that infect
Mycobacterium smegmatis
mc
2
155. Phages Findley, Hurricane, and TBond007 were discovered in geographically distinct locations and are related to cluster K mycobacteriophages, with Findley being similar to subcluster K2 phages and Hurricane and TBond007 being similar to subcluster K3 phages.
Complete Genome Sequence of Indigo-Producing Bacterium
Celeribacter
sp. Strain TSPH2
Authors: Kim Hae-Seon , Cha Sun Ho , Suk Ho Young , Kwon Tae-Hyung , Woo Jung-Hee 
Published: November 2017

ABSTRACT

Celeribacter
sp. strain TSPH2, a novel producer of indigo, was isolated from oil-contaminated sediment. We present here its genome sequence consisting of one circular chromosome (4 Mb) and one plasmid (0.15 Mb), with an overall G+C content of 60.9%. This strain contains oxygenase genes involved in indigo synthesis, such as flavin-containing monooxygenase.
Draft Genome Sequence of Burkholderia contaminans 293K04B, an Endosymbiont of the Sponge-Derived Fungus
Stachylidium bicolor
Authors: Fisch Katja M. , Silva Pereira Cristina , Genilloud Olga , Almeida Celso , Schäberle Till F. 
Published: November 2017

ABSTRACT

Here, we present the draft genome of the endofungal symbiotic bacterium
Burkholderia contaminans
293K04B, isolated from
Stachylidium bicolor
293K04 (Ascomycota). The fungus was originally isolated from the sponge
Callyspongia
cf.
C. flammea
.
S. bicolor
293K04 produces the endolides A-B, bioactive cyclic peptides possibly biosynthesized by its endobacterium
B. contaminans
293K04B.
Draft Genome Sequences of Clinical and Nonclinical Isolates of
Klebsiella
spp. Exhibiting Nonheritable Tolerance toward Antimicrobial Compounds
Authors: Patole Shashank , Mishra Mitali , Mohapatra Harapriya 
Published: November 2017

ABSTRACT

A clinical isolate and a nonclinical isolate of
Klebsiella pneumoniae
were found to exhibit nonheritable tolerance in response to antimicrobial compounds. The draft genome sequences of both isolates are presented here.