bluuebunny/crossref_metadata_2025_split huggingface dataset:
The burden of healthcare-associated infections in New Zealand public hospitals 2021
Authors: Morris Arthur J. , Hensen Mike , Graves Nicholas , Cai Yiying , Wolkewitz Martin , Roberts Sally A. , Grae Nikki 
Published: October 2024

AbstractBackground:There are no contemporary data on the burden of healthcare-associated infections (HAIs) in New Zealand.Objectives:To estimate the economic burden of HAIs in adults in New Zealand public hospitals by number and monetary value of bed days lost; number of deaths, number of life years lost, and the monetary value (in NZ dollars); Accident Compensation Commission (ACC) HAI treatment injury payments; and disability-adjusted life years (DALYs).Methods:The annual incidence rate was calculated from the observed prevalence of HAIs in New Zealand, and length of patient stays. Total HAIs for 2021 were estimated by multiplying adult admissions by incidence rates. The excess length of stay and mortality risk attributed to those with HAI was calculated using a multistate model. Payments for treatment injuries were obtained from the ACC. DALYs for HAIs were estimated from the literature.Results:The incidence rate of HAI was 4.74%, predicting 24,191 HAIs for 2021, resulting in 76,861 lost bed days, 699 deaths, with 9,371 years of life lost (YoLL). The annual economic burden was estimated to be $955m comprised of $121m for lost bed days, $792m for cost of YoLL, and $43m ACC claims. There were 24,165 DALY which is greater than many other measured injuries in New Zealand, eg motor vehicle traffic crashes with 20,328 DALY.Conclusions:HAIs are a significant burden for patients, their families, and the public health system. Preventive guidelines for many HAIs exist and a strategic plan is needed to reduce HAIs in New Zealand.
Postoperative outcomes after receipt of ertapenem antimicrobial prophylaxis for colon surgery: a multicenter retrospective cohort study
Authors: Hostler Christopher J. , Krishnan Jay , Parish Alice , Baroco Allison , Cooper Penny , Donceras Onofre , Lautenbach Ebbing , Tolomeo Pam , Sansossio Tracy , Santos Carlos A.Q. , Schwartz David , Zhang Helen , Welbel Sharon , Lokhnygina Yuliya , Anderson Deverick J. ,   for the CDC Prevention Epicenters Program
Published: October 2024

AbstractObjective:To evaluate postoperative outcomes among patients undergoing colon surgery who receive perioperative prophylaxis with ertapenem compared to other antibiotic regimens.Design and setting:Multicenter retrospective cohort study among adults undergoing colon surgery in seven hospitals across three health systems from 1/1/2010 to 9/1/2015.Methods:Generalized linear mixed logistic regression models were applied to assess differential odds of select outcomes among patients who received perioperative prophylaxis with ertapenem compared to other regimens. Postoperative outcomes of interest included surgical site infection (SSI), Clostridioides difficile infection (CDI) and clinical culture positivity for carbapenem-resistant Enterobacteraciae (CRE). Inverse probability weights were applied to account for differing covariate distributions across ertapenem and non-ertapenem groups.Results:A total of 2,109 patients were included for analysis. The odds of postoperative SSI was 1.56 times higher among individuals who received ertapenem than among those receiving other perioperative antimicrobial prophylaxis regimens in our cohort (46 [3.5%] vs 20 [2.5%]; IPW-weighted OR 1.56, [95% CI, 1.08–2.26], P = .02). No statistically significant differences in odds of postoperative CDI (24 [1.8%] vs 16 [2.0%]; IPW-weighted OR 1.07 [95% CI, .68–1.68], P = .78) were observed between patients who received ertapenem prophylaxis compared to other regimens. Clinical CRE culture positivity was rare in both groups (.2%–.5%) and did not differ statistically.Conclusions:Ertapenem use for perioperative prophylaxis was associated with increased odds of SSI among patients undergoing colon surgery in our study population, though no differences in CDI or clinical CRE culture positivity were identified. Further study and replication of these findings are needed.
Imperial mission: Jesuits, French diplomacy, and medical education at l’Aurore University in Shanghai, 1912–1952
Authors: Pieragastini Steven , Robert Martin 
Published: October 2024

AbstractBetween 1903 and 1952, there was a Jesuit and French university in Shanghai called l’Aurore. This article focuses on its medical faculty, which operated from 1912 to 1952. It shows that, in a precarious political and military context, l’Aurore simultaneously benefited from Jesuit missionary activity and the French quest for imperial influence, without fully identifying with either. The faculty was not an official missionary institution, and most of its hundreds of students were not Christians. However, the Jesuit administration kept a record of baptisms among the students and, based on Catholic principles, encouraged opposition to birth control through courses on ‘medical ethics’ and a special oath that medical graduates had to take. Nor was the medical faculty an overtly imperial institution. It was part of a concession and the result of an alliance between Jesuit missionaries and anti-clerical diplomats of the French Third Republic. Yet, the faculty was key to a French policy of imperial influence designed to compete with other imperial, religious, and private foreign powers active in medical education in China. During the years of war between China and Japan (1937–1945), the faculty consolidated its influence by increasing student numbers and building new infrastructure, whereas its Chinese staff assumed a more prominent role, reinforcing the importance of Chinese medicine in teaching and research. Doctors trained at l’Aurore who stayed in China remained active in public health until well into the second half of the twentieth century, even after the medical faculty was abolished by the Communist regime.
Evaluating the effects of dietary patterns on circulating C-reactive protein levels in the general adult population: an umbrella review of meta-analyses of interventional and observational studies
Authors: Tran Duc Quang , Nguyen Di Khanh , Quynh Chi Vu Thi , Nguyen Huyen Thi Hoa 
Published: October 2024

AbstractAdopting a healthy dietary pattern may be an initial step in combating inflammation-related chronic diseases; however, a comprehensive synthesis evaluating current evidence is lacking. This umbrella review aimed to summarise the current evidence on the effects of dietary patterns on circulating C-reactive protein (CRP) levels in adults. We conducted an exhaustive search of the Pubmed, Scopus and Epistemonikos databases, spanning from their inception to November 2023, to identify systematic reviews and meta-analyses across all study designs. Subsequently, we employed a random-effects model to recompute the pooled mean difference. Methodological quality was assessed using the A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2) checklist, and evidence certainty was categorised as non-significant, weak, suggestive, highly suggestive or convincing (PROSPERO: CRD42023484917). We included twenty-seven articles with thirty meta-analyses of seven dietary patterns, fifteen of which (50 %) exhibited high methodological quality. The summary effects of randomised controlled trials (RCT) found that the Mediterranean diet was the most effective in reducing circulating CRP levels, followed by Vegetarian/Vegan and Energy-restricted diets, though the evidence was of weak quality. In contrast, Intermittent Fasting, Ketogenic, Nordic and Paleolithic diets did not show an inverse correlation with circulating CRP levels. Some results from combined interventional and observational studies, as well as solely observational studies, also agreed with these findings. These dietary patterns show the potential in reducing CRP levels in adults, yet the lack of high-quality evidence suggests future studies may alter the summary estimates. Therefore, further well-conducted studies are warranted.
Taurine/chenodeoxycholic acid ratio as a potential serum biomarker for low vitamin B12 levels in humans
Authors: Baghel Madhu , Shi Sting L. , Patel Himani , Velagapudi Vidya , Ali Abdullah Mahmood , Yadav Vijay K. 
Published: October 2024

AbstractDeficiency of vitamin B12 (B12 or cobalamin), an essential water-soluble vitamin, leads to neurological damage, which can be irreversible and anaemia, and is sometimes associated with chronic disorders such as osteoporosis and cardiovascular diseases. Clinical tests to detect B12 deficiency lack specificity and sensitivity. Delays in detecting B12 deficiency pose a major threat because the progressive decline in organ functions may go unnoticed until the damage is advanced or irreversible. Here, using targeted unbiased metabolomic profiling in the sera of subjects with low B12 levels v control individuals, we set out to identify biomarker(s) of B12 insufficiency. Metabolomic profiling identified seventy-seven metabolites, and partial least squares discriminant analysis and hierarchical clustering analysis showed a differential abundance of taurine, xanthine, hypoxanthine, chenodeoxycholic acid, neopterin and glycocholic acid in subjects with low B12 levels. Random forest multivariate analysis identified a taurine/chenodeoxycholic acid ratio, with an AUC score of 1, to be the best biomarker to predict low B12 levels. Mechanistic studies using a mouse model of B12 deficiency showed that B12 deficiency reshaped the transcriptomic and metabolomic landscape of the cell, identifying a downregulation of methionine, taurine, urea cycle and nucleotide metabolism and an upregulation of Krebs cycle. Thus, we propose taurine/chenodeoxycholic acid ratio in serum as a potential biomarker of low B12 levels in humans and elucidate using a mouse model of cellular metabolic pathways regulated by B12 deficiency.
Slavery, Mobility, and Identity on the Western Coast of India, Sixteenth–Eighteenth Centuries
Authors: Chakravarti Ananya 
Published: October 2024

AbstractIn the wake of the establishment of the Portuguese in the region, slavery was fundamentally constitutive of early modern society on the west coast of India. While indigenous hierarchies and existing systems of slavery shaped Portuguese slavery, over time, indigenous society too was transformed by the extensive reliance on enslaved labor facilitated by European trafficking networks. Centering slavery in the study of South Asian history underscores the importance of considering the difference between elite projects of enforcing boundaries, both spatial and social, and the ways in which enslaved people negotiated these projects. Thus, instead of taking for granted the classificatory labels of race, caste, and blackness imposed upon enslaved peoples by elite institutions, a social history of slavery elucidates instead the evolution of these mechanisms for policing identity, and the centrality of the expropriation of labor in identity formation.
Complex PTSD symptoms predict positive symptoms of psychosis in the flow of daily life
Authors: Panayi Peter , Peters Emmanuelle , Bentall Richard , Hardy Amy , Berry Katherine , Sellwood William , Dudley Robert , Longden Eleanor , Underwood Raphael , Steel Craig , Jafari Hassan , Emsley Richard , Mason Liam , Elliott Rebecca , Varese Filippo 
Published: October 2024

AbstractBackgroundPost-traumatic stress disorder (PTSD) has been shown to predict psychotic symptomology. However, few studies have examined the relative contribution of PTSD compared to broader post-traumatic sequelae in maintaining psychosis. Complex PTSD (cPTSD), operationalized using ICD-11 criteria, includes core PTSD (intrusions, avoidance, hyperarousal) as well as additional “disturbances of self-organisation” (DSO; emotional dysregulation, interpersonal difficulties, negative self-concept) symptoms, more likely to be associated with complex trauma histories. It was hypothesized that DSOs would be associated with positive psychotic symptoms (paranoia, voices, and visions) in daily life, over and above core PTSD symptoms.MethodsThis study (N = 153) employed a baseline subsample of the Study of Trauma And Recovery (STAR), a clinical sample of participants with comorbid post-traumatic stress and psychosis symptoms. Core PTSD, DSO and psychosis symptoms were assessed up to 10 times per day at quasi-random intervals over six consecutive days using Experience Sampling Methodology.ResultsDSOs within the preceding 90 min predicted paranoia, voices, and visions at subsequent moments. These relationships persisted when controlling for core PTSD symptoms within this timeframe, which were themselves significant. The associations between DSOs and paranoia but not voices or visions, were significantly stronger than those between psychosis and core PTSD symptoms.ConclusionsConsistent with an affective pathway to psychosis, the findings suggest that DSOs may be more important than core PTSD symptoms in maintaining psychotic experiences in daily life among people with comorbid psychosis and cPTSD, and indicate the potential importance of addressing broad post-traumatic sequelae in trauma-focused psychosis interventions.
Auguste Valensin
Authors: Blount M.M. 
Published: October 2024

In a time as overshadowed as our own by the angst of the day and its despair, there has recently been published, among many inspiring Catholic works, one which in a sense is unique, antidote, it might be termed a counterblast, to anguish. A paris journal announces its sale up-to-date of sixty thousand copies.By the late Auguste Valensin, S.J., famous abroad if scarcely known to the general public in this country, by no means the least of the facets of its unique quality is the fact that the book consists of the personal meditations, without ‘points’ or formalities of any kind, written day by day, by someone of obvious holiness and culture, published since his death in 1953.To those of us nurtured in any degree on the too-usual style of much of earlier French spiritual writing, this may be far from an alluring introduction.
The extraordinary “ordinary magic” of resilience
Authors: Grigorenko Elena L. 
Published: October 2024

AbstractIn this essay, I will briefly sample different instances of the utilization of the concept of resilience, attempting to complement a comprehensive representation of the field in the special issue of Development and Psychopathology inspired by the 42nd Minnesota Symposium on Child Psychology, hosted by the Institute of Child Development at the University of Minnesota and held in October of 2022. Having established the general context of the field, I will zoom in on some of its features, which I consider “low-hanging fruit” and which can be harvested in a systematic way to advance the study of resilience in the context of the future of developmental psychopathology.
Parenting stress and child behavior problems: Developmental psychopathology perspectives
Authors: Crnic Keith A. 
Published: October 2024

AbstractThe growing base of research on parenting stress and its relation to child behavior problems has largely paralleled the emergence of developmental psychopathology as a field of inquiry. Specifically, the focus on mechanism rather than main effects has begun to elevate explanatory models in the connection between parenting stress and a variety of adverse child and parent conditions. Still, work on parenting stress is limited by conceptual confusion, the absence of attention to developmental differentiation, a focus on child-specific rather than system influences. Recent research on these parenting stress issues is briefly reviewed, highlighting studies that have illustrated developmental psychopathology perspectives. A conceptual model is offered to illustrate the complex recursive nature of connections between parenting stress, parenting behavior, parent well-being, and children’s adjustment, and I make a case for the adoption of a more systemic perspective to influence the next generation of developmental psychopathology research on parenting stress.
An account of the kings of Kanu'l as recorded on the hieroglyphic stair of K'an II of Caracol
Authors: Helmke Christophe , Vepretskii Sergei 
Published: October 2024

AbstractMany questions remain about the hieroglyphic stair dedicated in a.d. 642 by K'an II, the great king of Caracol. Constituent panels have been found at Caracol, Ucanal, Naranjo, and Xunantunich—archaeological sites spread between Guatemala and Belize. The most recently discovered Panels 3 and 4 at Xunantunich shed light on the tumultuous decades of the seventh century. Panel 4, which opened the hieroglyphic stair, makes a surprising statement from the outset, clarifying that Kanu'l political authority was irrevocably established at Calakmul. This bold statement serves as a synoptic précis for the entire narrative and explains why the deeds of K'an II are related, but only to the extent that these could be interwoven with the history of the Kanu'l. This makes the hieroglyphic stair such an important source, because it tracks the rulers of the Kanu'l dynasty from the vantage of a close ally. These monuments attest to the fissioning of the Kanu'l dynasty and its eventual restoration at Calakmul, from whence Classic Maya politics would be overseen for the remainder of the seventh century. In this article, we build on earlier studies and add our most recent observations and new readings based on renewed inspections of the existing panels.
Patent ductus arteriosus closure in small infants weighing less than 1500 g using KA micro plug: steps and tips
Authors: Mohammad Nijres Bassel , Hassan Moeez , Windsor Jimmy , Bischoff Adrianne Rahde , McNamara Patrick J. , Aldoss Osamah 
Published: October 2024

AbstractBackground:Transcatheter patent ductus arteriosus closure in premature infants is gaining attention with rapidly growing experience. The KA micro plug device poses many favourable features for ductus arteriosus closure in premature infants. The study aimed to describe the technique and outcomes of a KA micro plug in closing the ductus arteriosus in premature infants weighing less than 1500 g.Methods:This is a single-centre retrospective study in premature infants with patent ductus arteriosus weighing less than 1500 g who underwent off-label use of a KA micro plug at the Stead Family Children’s Hospital from February 2022 to December 2023.Results:Eighteen premature infants weighing less than 1500 g underwent attempted transcatheter ductus arteriosus closure using a KA micro plug device. Median weight, age, and corrected gestational age at the procedure were 943 g (682–1225), 26 days (9–79), and 28.5 weeks (25.6–32), respectively. The procedure was successful with complete closure achieved in all patients. No major haemodynamic instabilities were encountered. No catheterization-related complications were encountered. On a median follow-up of 10.9 months (0.1–19), all patients are alive with the device in a good position without residual shunt or abnormal findings.Conclusion:KA micro plug device for patent ductus arteriosus in infants weighing less than 1500 g is feasible, safe, and effective. We recommend that manufacturers of devices used to close the ductus arteriosus in small infants enhance both the devices and their delivery systems to simplify the procedure and mitigate the risk of haemodynamic instability.
Adherence to the EAT-Lancet sustainable diet and ultra-processed food consumption: findings from a nationwide population-based study in Brazil
Authors: Cacau Leandro Teixeira , Souza Thays Nascimento , Louzada Maria Laura da Costa , Marchioni Dirce Maria Lobo 
Published: October 2024

Abstract

Objective:
To evaluate the association between ultra-processed food consumption and adherence to the EAT-Lancet diet in a representative sample of the Brazilian population.

Design:
The study used data from the Brazilian National Dietary Survey 2017–2018 and employed linear regression models to evaluate the association between ultra-processed food consumption and adherence to the EAT-Lancet diet, as measured by the Nova food system and Planetary Health Diet Index (PHDI), respectively.

Setting:
Nationally representative sample of the Brazilian population.

Participants:
The study included 46 164 Brazilians ≥ 10 years old.

Results:
The average PHDI total score was 45·9 points (95 % CI 45·6, 46·1). The ultra-processed food consumption was, with dose-response, inversely associated with the adherence to the EAT-Lancet diet. The PHDI total score was 5·38 points lower (95 % CI –6·01, –4·75) in individuals in the highest quintile of consumption of ultra-processed foods, as compared to those in the first quintile. The PHDI score was also inversely associated with the share of processed culinary ingredients and processed foods and positively associated with the share of unprocessed or minimally processed foods.

Conclusions:
Our study showed an inverse relationship between the consumption of ultra-processed foods and the adherence to a healthy and sustainable diet.
Limitations of hypocrisy as a strategy of critique in international politics
Authors: Millar Katharine M. 
Published: October 2024

AbstractHypocrisy, when addressed at all, is typically considered a functional, even valuable, aspect of international political practice within international relations theory. It is alternatively seen as necessary to the exercise of sovereignty and a rhetorical device used to seek pragmatic political change. Utilising insights from feminist, queer, and postcolonial theory, this article challenges this understanding of hypocrisy. The article demonstrates that hypocrisy is animated and elided by an investment in a particularly liberal vision of politics and international order (and concomitant obfuscation of the racialised, sexual, gendered, and colonial underpinnings of those same assumptions). The notion of hypocrisy relies upon a unitary and stable subject whose moral consistency is to be expected across time and space – a luxury less afforded to those disadvantaged within intersectional international hierarchies. Consequently, although the charge of hypocrisy appears to be about holding power to account, the article finds that it serves less to uphold normative principles than to re-centre the privileged and powerful subject – typically, the sovereign state of liberal international order – and its consistency with itself, as the unit and basis of moral concern. The article concludes by outlining the limitations of hypocrisy as a strategy of critique.
Kongomania and the Haitian Revolution
Authors: Geggus David 
Published: October 2024

AbstractThe article critiques the scholarly emphasis on the centrality of West-Central Africans in the Haitian Revolution. It argues that two highly influential articles published 30 years ago by John Thornton greatly exaggerated the presence of such “Congos” in the colony, and overstated that of Africans in general. Amplified in subsequent works by Thornton and others, this exaggeration has become the prevailing orthodoxy and the issue has gone entirely unnoticed down to today. To make its point, the article draws on a data set of more than 31,000 enslaved workers of known origin and it attempts to calculate population change on the eve of the revolution. It lays out the way the ethnic composition of the black population varied by crop type and region, and produces for the first time estimates for the whole of Saint Domingue. It additionally makes two excursions into African studies. The first is to investigate the ethnic/geographic origins of the “Congos.” The second relates to the nature of slavery in West-Central Africa and certain items of Kikongo vocabulary. This forms part of a critique of an ambitious article by James Sweet concerning the influence of Kongolese in Saint-Domingue that constitutes the article's final section.