bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photonic Crystal Phosphors Integrated on a Blue LED Chip for Efficient White Light Generation
Authors: Lee Jongho , Min Kyungtaek , Park Yeonsang , Cho Kyung‐Sang , Jeon Heonsu 
Published: November 2017

AbstractFollowing the proof‐of‐concept experiment in the unit structure level, photonic crystal (PhC) phosphors—structurally engineered phosphor materials based on the nanophotonics principles—are integrated with a blue light‐emitting diode (LED) chip to demonstrate a compact and efficient white light source. Red‐ or green‐emitting CdSe‐based colloidal quantum dots (CQDs) are coated on a Si3N4 thin‐film grating to fabricate PhC phosphors. The underlying PhC structure is designed such that the photonic band‐edge modes at the zone center (k∣∣ = 0) are tuned to the energy of the blue excitation photons. By progressively stacking the PhC phosphor plates on a blue LED chip, the blue, green, and red emission intensities can be tightly controlled to obtain white light with the desired properties. The chromaticity coordinates, (0.332, 0.341), and correlated color temperature, 5500 K, are obtained from a stack of 3 red and 11 green PhC phosphor plates; in contrast, a stack of 5 red and 16 green reference phosphor plates are required to generate a similar white light. Overall, the PhC phosphors produce 8% higher total emission intensity out of 33% less amount of CQDs than the reference phosphors.
High‐Efficiency Dielectric Metasurfaces for Polarization‐Dependent Terahertz Wavefront Manipulation
Authors: Zhang Huifang , Zhang Xueqian , Xu Quan , Tian Chunxiu , Wang Qiu , Xu Yuehong , Li Yanfeng , Gu Jianqiang , Tian Zhen , Ouyang Chunmei , Zhang Xixiang , Hu Cong , Han Jiaguang , Zhang Weili 
Published: November 2017

AbstractRecently, metasurfaces made up of dielectric structures have drawn enormous attentions in the optical and infrared regimes due to their high efficiency and designing freedom in manipulating light propagation. Such advantages can also be introduced to terahertz frequencies where efficient functional devices are still lacking. Here, polarization‐dependent all‐silicon terahertz dielectric metasurfaces are proposed and experimentally demonstrated. The metasurfaces are composed of anisotropic rectangular‐shaped silicon pillars on silicon substrate. Each metasurface holds dual different functions depending on the incident polarizations. Furthermore, to suppress the reflection loss and multireflection effect in practical applications, a high‐performance polarization‐independent antireflection silicon pillar array is also proposed, which can be patterned at the other side of the silicon substrate. Such all‐silicon dielectric metasurfaces are easy to fabricate and can be very promising in developing next‐generation efficient, compact, and low‐cost terahertz functional devices.
Unraveling Geometrical Site Confinement in Highly Efficient Iron‐Doped Electrocatalysts toward Oxygen Evolution Reaction
Authors: Hung Sung‐Fu , Hsu Ying‐Ya , Chang Chia‐Jui , Hsu Chia‐Shuo , Suen Nian‐Tzu , Chan Ting‐Shan , Chen Hao Ming 
Published: November 2017

AbstractIntroduction of iron in various catalytic systems has served a crucial function to significantly enhance the catalytic activity toward oxygen evolution reaction (OER), but the relationship between material properties and catalysis is still elusive. In this study, by regulating the distinctive geometric sites in spinel, Fe occupies the octahedral sites (Fe3+(Oh)) and confines Co to the tetrahedral site (Co2+(Td)), resulting in a strikingly high activity (ηj = 10 mA cm−2 = 229 mV and ηj = 100 mA cm−2 = 281 mV). Further enrichment of Fe ions would occupy the tetrahedral sites to decline the amount of Co2+(Td) and deteriorate the OER activity. It is also found that similar tafel slope and peak frequency in Bode plot of electrochemical impedance spectroscopy indicate that Co2+(Td) ions are primarily in charge of water oxidation catalytic center. By means of electrochemical techniques and in situ X‐ray absorption spectroscopy, it is proposed that Fe3+(Oh) ions mainly confine cobalt ions to the tetrahedral site to restrain the multipath transfer of cobalt ions during the dynamic structural transformation between spinel and oxyhydroxide, continuously activating the catalytic behavior of Co2+(Td) ions. This material‐related insight provides an indication for the design of highly efficient OER electrocatalysts.
Brass and Bronze as Effective CO2 Reduction Electrocatalysts
Authors: He Jingfu , Dettelbach Kevan E. , Huang Aoxue , Berlinguette Curtis P. 
Published: November 2017

AbstractElectrochemically reducing CO2 into fuels using renewable electricity is a contemporary global challenge that requires significant advances in catalyst design. Photodeposition techniques were used to screen ternary alloys of Cu‐Zn‐Sn, which includes brass and bronze, for the electrocatalytic reduction of CO2 to CO and formate. This analysis identified Cu0.2Zn0.4Sn0.4 and Cu0.2Sn0.8 to be capable of reaching Faradaic efficiencies of >80 % for CO and formate formation, respectively, and capable of achieving partial current densities of 3 mA cm−2 at an overpotential of merely 200 mV.
Shape‐Controllable and Fluorescent Supramolecular Organic Frameworks Through Aqueous Host–Guest Complexation
Authors: Li Yawen , Dong Yunhong , Miao Xiaran , Ren Yulin , Zhang Beilin , Wang Pinpin , Yu Yang , Li Bin , Isaacs Lyle , Cao Liping 
Published: November 2017

AbstractTwo kinds of shape‐controllable and fluorescent supramolecular organic frameworks (cuboid or spheroid) are constructed hierarchically from CB[8] and tetraphenylethylene derivatives through host–guest interaction in water. These two fluorescent SOFs exhibit intriguing and varied photophysical properties, including large red‐shifts (up to 82 nm) and stimuli‐responsive behavior to competitive guest by binding with CB[8], the turn‐on fluorescence of which is applied in cellular imaging.
Chagosendines A – C, New Metal Complexes of Imidazole Alkaloids from the Calcareous Sponge Leucetta chagosensis
Authors: An Bang , Yin Fuling , de Voogd Nicole J. , Chen Xiaoguang , Cheng Wei , Lin Wenhan 
Published: November 2017

Chemical examination of the bright yellow sponge Leucetta chagosensis resulted in the isolation of three new imidazole‐based alkaloid complexes namely chagosendines A – C (1 – 3), together with known analogues pyronaamidine, naamidine J, and naamine C. Their structures were determined on the basis of extensive spectroscopic (IR, MS, NMR, and single‐crystal X‐ray diffraction) analysis in association with the chemical conversion. The isolated alkaloids together with three synthesized new homodimer complexes were evaluated for the cytotoxic activities against a panel of tumor cell lines. The copper complexes of imidazole alkaloids 2 and 3, as found from nature for the first time, exerted selective and remarkable activities against the tumor cell lines K562, HepG2, and HeLa.
Plunging ranula: surgical management of case series and the literature review
Authors: Olojede Akanbi Clement Olurotimi , Ogundana Oladunni Mojirayo , Emeka Christian Ibesi , Adewole Richard Ayodeji , Emmanuel Mubarak Mobolade , Gbotolorun Olalekan Micah , Ayodele Adesina Olumuyiwa , Oluseye Sunday Babatunde 
Published: November 2017

Key Clinical MessagePlunging ranulas are rare; report of this condition is particularly limited in our environment. We present case series in children; with all cases having both oral and cervical components. It is important to note this type of presentation of plunging ranula and their appropriate management.
EBV‐associated hemophagocytic lymphohistiocytosis complicated by severe coagulation disorders and opportunistic infections: case report of a survivor
Authors: Saevels Kirsten , Robert Dominique , Van den Broeck Sylvie , Malfait Ronald , Gadisseur Alain , Jorens Philippe , Verlinden Anke 
Published: November 2017

Key Clinical MessageThe possibility of hemophagocytic lymphohistiocytosis should always be kept in mind when examining/treating a patient with fever of unknown origin and sepsis‐like symptoms. Early diagnosis leading to prompt initiation of immunosuppressive therapy as well as aggressive supportive care, including correction of coagulation abnormalities and treatment of opportunistic infections, can decrease mortality.
Phosphorus‐Doped MoS2 Nanosheets Supported on Carbon Cloths as Efficient Hydrogen‐Generation Electrocatalysts
Authors: Bian Luozhen , Gao Wei , Sun Jiamin , Han Mingming , Li Fulin , Gao Zhaofeng , Shu Lei , Han Ning , Yang Zai‐xing , Song Aimin , Qu Yongquan , Ho Johnny C. 
Published: November 2017

AbstractHighly efficient and stable non‐noble metal electrocatalysts for hydrogen generation are desired for sustainable development of energy conversion and storage. Here, a facile low‐temperature phosphidation process is developed for phosphorus doping into molybdenum disulfide (MoS2) nanosheets directly synthesized on carbon cloths to function as an integrated electrode for efficient hydrogen evolution reaction. The optimal phosphorus‐doped (3.3 at%) MoS2 nanosheets exhibit substantially lower overpotentials of 133 and 189 mV to drive the current densities of 20 and 100 mA cm‐2, respectively, as compared with undoped MoS2, and an impressively small Tafel slope of 67.0 mV dec−1. The excellent stability in acid media also makes the phosphorus‐doped MoS2 nanosheet catalysts promising candidates for hydrogen generation in practical applications.
Optical Properties and Sequence Information of Tin‐Centered Conjugated Microporous Polymers
Authors: Uptmoor Andrea C. , Ilyas Ruben , Elbert Sven M. , Wacker Irene , Schröder Rasmus R. , Mastalerz Michael , Freudenberg Jan , Bunz Uwe H. F. 
Published: November 2017

AbstractWe synthesized conjugated microporous polymers (CMPs) based on tetrakis(4‐ethynylphenyl)stannane and diiodobenzene as tectons, using Sonogashira couplings under different conditions. Through variation of the reaction conditions (catalysts, bases and solvents), appearance, surface area and emission properties of the formed CMPs were significantly altered. Wet‐chemical, acid‐mediated digestion and analysis of the resulting struts of these otherwise insoluble networks give insight into the molecular setup.
Drastic Effect of the Peptide Sequence on the Copper‐Binding Properties of Tripeptides and the Electrochemical Behaviour of Their Copper(II) Complexes
Authors: Mena Silvia , Mirats Andrea , Caballero Ana B. , Guirado Gonzalo , Barrios Leoní A. , Teat Simon J. , Rodriguez‐Santiago Luis , Sodupe Mariona , Gamez Patrick 
Published: November 2017

AbstractThe binding and electrochemical properties of the complexes CuII‐HAH, CuII‐HWH, CuII‐Ac‐HWH, CuII‐HHW, and CuII‐WHH have been studied by using NMR and UV/Vis spectroscopies, CV, and density functional calculations. The results obtained highlight the importance of the peptidic sequence on the coordination properties and, consequently, on the redox properties of their CuII complexes. For CuII‐HAH and CuII‐HWH, no cathodic processes are observed up to −1.2 V; that is, the complexes exhibit very high stability towards copper reduction. This behaviour is associated with the formation of very stable square‐planar (5,5,6)‐membered chelate rings (ATCUN motif), which enclose two deprotonated amides. In contrast, for non‐ATCUN CuII‐Ac‐HWH, CuII‐HHW complexes, simulations seem to indicate that only one deprotonated amide is enclosed in the coordination sphere. In these cases, the main electrochemical feature is a reductive irreversible one electron‐transfer process from CuII to CuI, accompanied with structural changes of the metal coordination sphere and reprotonation of the amide. Finally, for CuII‐WHH, two major species have been detected: one at low pH (<5), with no deprotonated amides, and another one at high pH (>10) with an ATCUN motif, both species coexisting at intermediate pH. The present study shows that the use of CV, using glassy carbon as a working electrode, is an ideal and rapid tool for the determination of the redox properties of CuII metallopeptides.
Highly Multiplexed Single‐Cell Protein Analysis
Authors: Mondal Manas , Liao Renjie , Guo Jia 
Published: November 2017

AbstractSingle‐cell proteomic analysis is crucial to advance our understanding of normal physiology and disease pathogenesis. The comprehensive protein profiling in individual cells of a heterogeneous sample can provide new insights into many important biological issues, such as the regulation of inter‐ and intracellular signaling pathways or the varied cellular compositions of normal and diseased tissues. With highly multiplexed molecular imaging of many different protein biomarkers in patient biopsies, diseases can be accurately diagnosed to guide the selection of the ideal treatment. In this Minireview, we will describe the recent technological advances of single‐cell proteomic assays, discuss their advantages and limitations, highlight their applications in biology and precision medicine, and present the current challenges and potential solutions.
Binding of Hydrophobic Guests in a Coordination Cage Cavity is Driven by Liberation of “High‐Energy” Water
Authors: Metherell Alexander J. , Cullen William , Williams Nicholas H. , Ward Michael D. 
Published: November 2017

AbstractInvited for the cover of this issue is the group of Michael D. Ward at the Universities of Warwick and Sheffield. The image depicts the ‘hydrophobic effect’ that is responsible for guest binding in the host cavity. Read the full text of the article at 10.1002/chem.201704163.
The peripheral nervous system of the ascidian tadpole larva: Types of neurons and their synaptic networks
Authors: Ryan Kerrianne , Lu Zhiyuan , Meinertzhagen Ian A. 
Published: November 2017

AbstractPhysical and chemical cues from the environment are used to direct animal behavior through a complex network of connections originating in exteroceptors. In chordates, mechanosensory and chemosensory neurons of the peripheral nervous system (PNS) must signal to the motor circuits of the central nervous system (CNS) through a series of pathways that integrate and regulate the output to motor neurons (MN); ultimately these drive contraction of the tail and limb muscles. We used serial‐section electron microscopy to reconstruct PNS neurons and their hitherto unknown synaptic networks in the tadpole larva of a sibling chordate, the ascidian, Ciona intestinalis. The larva has groups of neurons in its apical papillae, epidermal neurons in the rostral and apical trunk, caudal neurons in the dorsal and ventral epidermis, and a single tail tip neuron. The connectome reveals that the PNS input arises from scattered groups of these epidermal neurons, 54 in total, and has three main centers of integration in the CNS: in the anterior brain vesicle (which additionally receives input from photoreceptors of the ocellus), the motor ganglion (which contains five pairs of MN), and the tail, all of which in turn are themselves interconnected through important functional relay neurons. Some neurons have long collaterals that form autapses. Our study reveals interconnections with other sensory systems, and the exact inputs to the motor system required to regulate contractions in the tail that underlie larval swimming, or to the CNS to regulate substrate preference prior to the induction of larval settlement and metamorphosis.
Bio‐inspired Photocatalytic Ruthenium Complexes: Synthesis, Optical Properties, and Solvatochromic Effect
Authors: Weissman Adam , Amir Dan , Elias Yuval , Pinkas Iddo , Mathias Jenny‐Lee , Benisvy Laurent , Salomon Adi 
Published: November 2017

AbstractWe report the synthesis, characterization, and photo‐physical properties of two new rutheniumII‐phenol‐imidazole complexes. These bio‐mimetic complexes have potential as photocatalysts for water splitting. Owing to their multiple phenol‐imidazole groups, they have a higher probability of light‐induced radical formation than existing complexes. The newly synthesized complexes show improved overlap with the solar spectrum compared to other rutheniumII‐phenol‐imidazole complexes, and their measured lifetimes are suitable for light‐induced radical formation. In addition, we conducted solvatochromic absorption measurements, which elegantly follow Marcus theory, and demonstrate the symmetry differences between the two complexes. The solvatochromic measurements further imply electron localization onto one of the ligands. The new complexes may find applications in photocatalysis, dye‐sensitized solar cells, biomedicine, and sensing. Moreover, their multiple chelating units make them promising candidates for light‐activated metal organic radical frameworks, i.e. metal‐organic frameworks that contain organic radicals activated by light.
A high‐voltage gain nonisolated noncoupled inductor based multi‐input DC‐DC topology with reduced number of components for renewable energy systems
Authors: Varesi Kazem , Hosseini Seyed Hossein , Sabahi Mehran , Babaei Ebrahim 
Published: November 2017

SummaryThis paper proposes a modular nonisolated noncoupled inductor‐based high‐voltage gain multi‐input DC‐DC converter. Despite the high‐voltage gain of the proposed topology, the average of normalized voltage stress (NVS) on its switches/diodes is low. This property leads to less loss and cost of switches/diodes. Using the same number of components, the proposed topology produces higher voltage gains, in comparison with recently presented high step‐up topologies. Also, the proposed topology utilizes less number of components (capacitors, inductors, diodes, and switches) for producing a desired voltage gain, which can reduce the size, mass, cost, complexity, and losses and improve the efficiency of converter. Continuous current of input sources is another main advantage of the proposed topology. All the abovementioned characteristics have made the proposed topology very suitable for renewable energy systems (or even hybrid/electric vehicles). Design considerations of the proposed topology have also been presented. For better evaluation, the proposed topology has been compared with some of recently presented high step‐up structures, from viewpoints of producible voltage gain, number of components, and normalized voltage stress (NVS) on switches/diodes. Finally, the prototype of 2‐input version has been experimentally implemented. Obtained experimental results confirm appropriate performance of the proposed topology.
Sacubitril/valsartan reduces serum uric acid concentration, an independent predictor of adverse outcomes in PARADIGM‐HF
Authors: Mogensen Ulrik M. , Køber Lars , Jhund Pardeep S. , Desai Akshay S. , Senni Michele , Kristensen Søren L. , Dukát Andrej , Chen Chen‐Huan , Ramires Felix , Lefkowitz Martin P. , Prescott Margaret F. , Shi Victor C. , Rouleau Jean L. , Solomon Scott D. , Swedberg Karl , Packer Milton , McMurray John J.V. ,   on behalf of the PARADIGM‐HF Investigators and Committees
Published: November 2017

AimsElevated serum uric acid concentration (SUA) has been associated with an increased risk of cardiovascular disease, but this may be due to unmeasured confounders. We examined the association between SUA and outcomes as well as the effect of sacubitril/valsartan on SUA in patients with heart failure with reduced ejection fraction (HFrEF) in PARADIGM‐HF.Methods and resultsThe association between SUA and the primary composite outcome of cardiovascular death or heart failure (HF) hospitalization, its components, and all‐cause mortality was examined using Cox regression analyses among 8213 patients using quintiles (Q1–Q5) of SUA adjusted for baseline prognostic variables including estimated glomerular filtration rate (eGFR), diuretic dose, and log N‐terminal pro‐brain natriuretic peptide. Change in SUA from baseline over 12 months was also evaluated in each treatment group. Patients in Q5 (SUA ≥8.6 mg/dL) compared with Q1 (<5.4 mg/dL) were younger (62.8 vs. 64.2 years), more often male (88.7% vs. 63.1%), had lower systolic blood pressure (119 vs. 123 mmHg), lower eGFR (57.4 vs. 76.6 mL/min/1.73 m2), and greater diuretic use. Higher SUA was associated with a higher risk of the primary outcome (adjusted hazard ratios) Q5 vs. Q1 = 1.28 [95% confidence intervals (1.09–1.50), P = 0.003], cardiovascular death [1.44 (1.11–1.77), P = 0.001], HF hospitalization [1.37 (1.11–1.70), P = 0.004], and all‐cause mortality [1.36 (1.13–1.64), P = 0.001]. Compared with enalapril, sacubitril/valsartan reduced SUA by 0.24 (0.17–0.32) mg/dL over 12 months (P < 0.0001). Sacubitril/valsartan improved outcomes, irrespective of SUA concentration.ConclusionSerum uric acid concentration was an independent predictor of worse outcomes after multivariable adjustment in patients with HFrEF. Compared with enalapril, sacubitril/valsartan reduced SUA and improved outcomes irrespective of SUA.
Estimating the number of potential family members eligible for BRCA1 and BRCA2 mutation testing in a “Traceback” approach
Authors: Moss Haley A. , Samimi Goli , Havrilesky Laura J. , Sherman Mark E. , Myers Evan R. 
Published: November 2017

ABSTRACTU.S. guidelines recommend BRCA1/2 mutation testing for women diagnosed with high‐grade ovarian cancer (HGOC) to increase recognition of carriers, but most remain unidentified and at risk. Accordingly, an approach termed “Traceback” has been proposed in which probands are retrospectively identified by testing archived pathology specimens, and family members are traced to provide genetic counseling and testing. We used population‐based data to estimate the number of family members who might be contacted through such a program. We used incidence data from the Surveillance, Epidemiology, and End Results (SEER) Program to estimate the number of women diagnosed with HGOC from 2005 to 2016, and census data to estimate the number of spouses, offspring, and siblings (both sexes). Using overall survival for HGOC from SEER and all‐cause mortality rates from the Centers for Diseases Control and Prevention, we estimated the number of patients, spouses, offspring, and siblings of HGOC cases living in 2017. Due to the high mortality rate of HGOC, consent from living probands may be possible in only 42% of the cases; consent to test pathology specimens would need to be sought from next of kin for the remainder. In 2017, an estimated 406,919 living next of kin (spouses, siblings, offspring) would be available for potential consent. Testing archived ovarian cancer pathology specimens may enable the identification of BRCA1/2 mutation carriers, but consent from next of kin would be required in in 58% of cases. Although Traceback offers the possibility of identifying unaffected BRCA1/2 mutation carriers, pilot feasibility studies that include assessment of methods to secure consent are needed.