bluuebunny/crossref_metadata_2025_split huggingface dataset:
PdCo Alloy Nanonetworks−Polyallylamine Inorganic–Organic Nanohybrids toward the Oxygen Reduction Reaction
Authors: Xu Guang‐Rui , Han Cong‐Cong , Zhu Ying‐Ying , Zeng Jing‐Hui , Jiang Jia‐Xing , Chen Yu 
Published: January 2018

AbstractRationally controlling the morphology, chemical composition, and interfacial property of metal nanostructures can remarkably enhance their electrocatalytic performance, such as activity, selectivity, and durability. In this work, a facile functional molecule‐assisted cyanogel‐reduction method is developed to successfully synthesize the polyallylamine (PAA)‐functionalized PdCo alloy nanonetworks (PdCo‐NNW@PAA) inorganic–organic nanohybrids. The solid, double‐metal, and 3D backbone properties of jelly‐like K2PdCl4/K3Co(CN)6 cyanogel intermediate contribute to the high alloying degree and network structure of PdCo‐NNW@PAA nanohybrids. During the reduction, PAA molecules not only serve as surfactant to decrease the particle size but also act as functional molecule to modify the metal surface. The oxygen reduction reaction (ORR) polarization and chronoamperometry tests demonstrate that PdCo‐NNW@PAA nanohybrids have outstanding electrocatalytic activity, excellent resistance to alcohol crossover effect, and good durability toward the ORR in alkaline media. This work provides a new strategy for synthesizing the chemical functionalized multimetallic alloy nanonetworks at room temperature and reveals that the interfacial property of metal nanocrystals strongly affects their electrocatalytic activity and selectivity.
Second‐Harmonic Spectroscopy for Defects Engineering Monitoring in Transition Metal Dichalcogenides
Authors: Rosa Henrique G. , Junpeng Lu , Gomes Lídia C. , Rodrigues Manuel J. L. F. , Haur Sow Chorng , Gomes José C. V. 
Published: January 2018

AbstractDefects engineering in transition metal dichalcogenides is a topic of intense research recently, since crystal properties can be controlled and tailored during and after fabrication. In this context, defects characterization is key to understand the material structure and enable specific applications. In this work, second‐harmonic generation (SHG) spectroscopy is used to map concentric triangular defective regions in as‐grown monolayer tungsten disulfide, demonstrating that SHG can be used for defects observation and characterization in layered noncentrosymmetric nanomaterials. In monolayer tungsten disulfide, in regions where sulfur atoms are replaced by vacancies, it is observed that the SHG signal experiences an enhancement of two orders of magnitude due to the presence of mid‐gap states. Moreover, SHG is anticorrelated with photoluminescence emission from the material, showing that both techniques can provide complementary information about the crystalline structure. In comparison with other optical characterization techniques, SHG provides fast response, does not depend on real energy transitions, and can be used for defects mapping in several other materials regardless the optical bandgap energy.
Heterogeneous impacts from a retail grocery acquisition: Do national and store brand prices respond differently?
Authors: Çakır Metin , Secor William G. 
Published: January 2018

AbstractWe investigate the extent to which a grocery retailer merger has different effects on the prices of national and store brands. Using retail scanner data, we retrospectively analyze a food retail acquisition in a large U.S. city. We focus on fluid milk and ready‐to‐eat (RTE) cereal categories, which represent a relatively homogenous and a relatively differentiated product category, respectively. We use a difference‐in‐difference estimation framework to obtain the causal effect of the acquisition on prices for the acquiring retailer. The primary finding is that the acquisition has heterogeneous price effects in the relatively differentiated RTE cereal category. The implications of results for consumers, food retailing, and merger analysis are discussed [EconLit citations: L11, L13, L22, L81].
Blue light‐emitting diodes induce autophagy in colon cancer cells by Opsin 3
Authors: Yoshimoto Toshiaki , Morine Yuji , Takasu Chie , Feng Rui , Ikemoto Tetsuya , Yoshikawa Kozo , Iwahashi Syuichi , Saito Yu , Kashihara Hideya , Akutagawa Masatake , Emoto Takahiro , Kinouchi Yosuke , Shimada Mitsuo 
Published: January 2018

AbstractBackgroundLight emitting‐diodes (LED) have various effects on living organisms and recent studies have shown the efficacy of visible light irradiation from LED for anticancer therapies. However, the mechanism of LED's effects on cancer cells remains unclear. The aim of the present study was to investigate the effects of LED on colon cancer cell lines and the role of photoreceptor Opsin 3 (Opn3) on LED irradiation in vitro.MethodsHuman colon cancer cells (HT‐29 or HCT‐116) were seeded onto laboratory dishes and irradiated with 465‐nm LED at 30 mW/cm2 for 30 minutes. Cell Counting Kit‐8 was used to measure cell viability, and apoptosis and caspase 3/8 expression were evaluated by AnnexinV/PI and reverse transcription‐polymerase chain reaction (RT‐PCR), respectively. Autophagy and expression of LC‐3 and beclin‐1 were also evaluated by autophagy assays, RT‐PCR and Western blotting. We further tested Opn3 knockdown by Opn3 siRNA and the Gi/o G‐protein inhibitor NF023 in these assays.ResultsViability of HT‐29 and HCT‐116 cells was lower in 465‐nm LED‐irradiated cultures than in control cultures. LC‐3 and beclin‐1 expressions were significantly higher in LED‐irradiated cultures, and autophagosomes were detected in irradiated cells. The reductive effect of cancer cell viability following blue LED irradiation was reversed by Opn3 knockdown or NF023 treatment. Furthermore, increased LC‐3 and beclin‐1 expression that resulted from blue LED irradiation was suppressed by Opn3 knockdown or NF023 treatment.ConclusionBlue LED irradiation suppressed the growth of colon cancer cells and Opn3 may play an important role as a photoreceptor.
Detection of gas components as a novel diagnostic method for colorectal cancer
Authors: Ishibe Atsushi , Ota Mitsuyoshi , Takeshita Akemi , Tsuboi Hiroshi , Kizuka Satoko , Oka Hidenori , Suwa Yusuke , Suzuki Shinsuke , Nakagawa Kazuya , Suwa Hirokazu , Momiyama Masashi , Watanabe Jun , Taguri Masataka , Kunisaki Chikara , Endo Itaru 
Published: January 2018

AbstractBackgroundThe fecal occult blood test (FOBT) is widely accepted as the most economic and non‐invasive screening method for colorectal cancer (CRC). However, the FOBT is inconvenient because it requires a fecal sample and shows limited accuracy. Alternatively, we hypothesized that fecal gas compounds from bowel movements may be a non‐invasive biomarker for CRC.MethodsGas compounds were collected from the bowel movements of 30 patients with CRC and from 26 healthy controls. The patient group comprised 17 males and 13 females, and the average age was 68 years. Additionally, 22 patients had colon cancer, and eight patients had rectal cancer. Gas compounds were analyzed using gas chromatography and compared with those from healthy controls.ResultsIn the gas analysis, methyl mercaptan was significantly higher in the CRC group than in the control group. Hydrogen was significantly lower in the CRC group than in the control group and was correlated with tumor depth and advanced disease stage. Sensitivity, specificity, and accuracy of detection by a discriminant formula were 90%, 57.7%, and 75%, respectively.ConclusionGas compounds from defecation constitute a promising, novel non‐invasive approach for CRC screening. (UMIN000028256)
Light‐Driven Shape‐Memory Porous Films with Precisely Controlled Dimensions
Authors: Wang Wei , Shen Dingfeng , Li Xiao , Yao Yuan , Lin Jiaping , Wang Aurelia , Yu Jiwoo , Wang Zhong Lin , Hong Suck Won , Lin Zhiqun , Lin Shaoliang 
Published: January 2018

AbstractShape‐memory polymers (SMPs) are an intriguing class of smart materials possessing reversible shape change and recovery capabilities. Effective routes to shape‐memory porous films (SMPFs) are few and limited in scope owing to the difficulty in manipulating the shape change of pores by conventional methods. Herein we report an unconventional strategy for crafting light‐driven SMPFs by judiciously constructing highly ordered porous films via a facile “breath figure” approach, followed by sequential vapor crosslinking and nondestructive directional light manipulation. Micropores can thus be transformed into other shapes including rectangle, rhombus and size‐reduced micropores at room temperature. The transformed micropores can be reverted to their original shapes by either thermal annealing or UV irradiation. As such, this strategy expands the rich diversity of SMPs accessible.
Dikationische E4‐Ketten (E=P, As, Sb, Bi) eingebettet in der Koordinationssphäre von Übergangsmetallen
Authors: Dütsch Luis , Fleischmann Martin , Welsch Stefan , Balázs Gábor , Kremer Werner , Scheer Manfred 
Published: January 2018

AbstractEs wird ein Vergleich der Oxidationschemie der Komplexe [{CpMo(CO)2}2(μ,η2:η2‐E2)] (E=P (A), As (B), Sb (C), Bi (D)) präsentiert. Die Oxidation von A–D mit [Thia]+ (=[C12H8S2]+) führt zur selektiven Bildung der dikationischen E4‐Komplexe [{CpMo(CO)2}4(μ4,η2:η2:η2:η2‐E4)]2+ (E=P (1), As (2), Sb (3), Bi (4)), die von vier [CpMo(CO)2]‐Fragmenten stabilisiert werden. Die Bildung der entsprechenden Monokationen [A]+, [C]+ und [D]+ konnte weder durch Cyclovoltammetrie noch durch EPR‐ oder NMR‐Spektroskopie nachgewiesen werden. Dies deutet auf eine schnelle Dimerisierung und keine Dissoziation in Lösung hin, was auch durch DFT‐Rechnungen prognostiziert wurde. Allerdings belegen EPR‐Messungen von 2 die Existenz geringer Mengen des Radikalkations [B]+ in Lösung. Die Einkristall‐Röntgenstrukturanalysen zeigen, dass die Produkte 1 und 2 im Festzustand eine Zickzack‐E4‐Kette aufweisen, wohingegen 3 und 4 über einen zentralen E4‐Käfig mit einer verzerrten, Butterfly‐artigen Geometrie verfügen. Darüber hinaus kann 1 einfach und reversibel in eine symmetrische und eine asymmetrische Form umgewandelt werden.
Active Intracellular Delivery of a Cas9/sgRNA Complex Using Ultrasound‐Propelled Nanomotors
Authors: Hansen‐Bruhn Malthe , de Ávila Berta Esteban‐Fernández , Beltrán‐Gastélum Mara , Zhao Jing , Ramírez‐Herrera Doris E. , Angsantikul Pavimol , Vesterager Gothelf Kurt , Zhang Liangfang , Wang Joseph 
Published: January 2018

AbstractDirect and rapid intracellular delivery of a functional Cas9/sgRNA complex using ultrasound‐powered nanomotors is reported. The Cas9/sgRNA complex is loaded onto the nanomotor surface through a reversible disulfide linkage. A 5 min ultrasound treatment enables the Cas9/sgRNA‐loaded nanomotors to directly penetrate through the plasma membrane of GFP‐expressing B16F10 cells. The Cas9/sgRNA is released inside the cells to achieve highly effective GFP gene knockout. The acoustic Cas9/sgRNA‐loaded nanomotors display more than 80 % GFP knockout within 2 h of cell incubation compared to 30 % knockout using static nanowires. More impressively, the nanomotors enable highly efficient knockout with just 0.6 nm of the Cas9/sgRNA complex. This nanomotor‐based intracellular delivery method thus offers an attractive route to overcome physiological barriers for intracellular delivery of functional proteins and RNAs, thus indicating considerable promise for highly efficient therapeutic applications.
Hybridization of Al2O3 microspheres and acrylic ester resins as a synergistic absorbent for selective oil and organic solvent absorption
Authors: Zhang Tao , Yue Xuejie , Yang Dongya , Guo Qing , Qiu Fengxian , Li Zhangdi 
Published: January 2018

In this study, we have focused on the synthesis, characterization, and oil absorption properties of Al2O3 microspheres/acrylic ester resin (AER) hybrids. The Al2O3 microspheres are prepared by a combined hydrothermal and sintering processes, followed by surface modification with silane coupling agent (KH 570). The Al2O3 microspheres/AER hybrids with a rough surface are synthesized by a microwave polymerization route by using modified Al2O3 microspheres as modifiers. In this hybrid materials system, the Al2O3 microspheres with porous structures may provide fast oil absorption due to the low oils absorption energy and short diffusion lengths. The resin hybrids exhibited reversible oils and organic solvents adsorption with maximum absorption capacities up to 29.85 g/g. This study suggests potential environmental advantage in using metal oxide microspheres in improving the oil absorption properties of oil‐absorbing resins as absorbents for recovering oil and organic solvent from water.
Untersuchungen zur Rissentstehung in den historischen Pfeilern der Elstertalbrücke Pirk
Authors: Keuser Manfred , Niederwald Michael 
Published: January 2018

AbstractDer Bau der Elstertalbrücke Pirk wurde im Jahr 1938 begonnen und 1940 kriegsbedingt eingestellt. Bis dahin waren die aus einem Stampfbetonkern und einer Granitmauerwerksschale bestehenden Pfeiler sowie die zwischen den Brückenpfeilern spannenden Gewölbebögen errichtet. Bis zur deutschen Wiedervereinigung blieb die Brücke aufgrund ihrer Lage im Grenzsperrgebiet der DDR ungenutzt und wurde im Jahr 1993 nach einer Sanierung durch die Herstellung der fehlenden Überbauten vervollständigt. Seitdem kam es im Bereich der Pfeilerköpfe zu einer vertikalen Rissbildung im Granitmauerwerk, die sich nach unten fortsetzt. Zur Feststellung der Rissursache wurden zunächst Finite‐Elemente‐Berechnungen durchgeführt, in denen das Tragverhalten und die Beanspruchungen der Pfeiler und insbesondere des Pfeilerkopfs untersucht wurden. Des Weiteren wurden nichtlineare Finite‐Elemente‐Simulationen eines Granitmauerwerksverbands vorgenommen, um die bis zur Bildung eines Risses übertragbaren Zugspannungen beurteilen zu können.
Performance‐Indikatoren für die Bewertung von Strukturen aus Konstruktionsbeton auf europäischer Ebene nach COST TU1406
Authors: Strauss Alfred , Ivankovic' Ana Mandic' , Mold Lisa , Bergmeister Konrad , Matos José C. , Casas Joan R. 
Published: January 2018

AbstractDas Qualitätsmanagement von Strukturen aus Stahl‐ und Spannbeton, insbesondere jener von Straßenbrücken unterscheidet sich innerhalb Europas stark von Staat zu Staat. Diese Publikation gibt nicht nur einen Überblick über den aktuellen Stand der Technik, sondern es wird ein Vorschlag für eine holistische Performance‐Bewertung von Brücken aus Konstruktionsbeton vorgestellt. Um die Vorgehensweise bei der Qualitätskontrolle von Straßenbrücken und infolgedessen die Entscheidungsfindung zur Umsetzung von Instandhaltungsmaßnahmen auf einen einheitlichen Standard zu bringen, hat sich das europäsche Forschungsprojekt COST (European Cooperation in Science & Technology) Action TU1406 zum Ziel gesetzt, eine in Europa allgemein gültige Richtlinie zur Erstellung von Qualitätskontrollplänen zu entwickeln. Die COST TU 1406 befasst sich mit der Erhebung der für die Zustandsbeurteilung von Straßenbrücken relevanten Leistungsindikatoren (performance indicators). Um Daten in Bezug auf diese Performance‐Indikatoren zu sammeln, wurden die Mitgliedsstaaten der COST Action ersucht, sämtliche Informationen aus bereits in Anwendung befindlichen Dokumenten, wie Richtlinien und Normen, sowie aus Forschungsdokumenten zu erheben. In diesem Beitrag werden die Prozesse hinsichtlich der Erhebung und Dokumentation der Daten sowie deren Evaluierung eingehend beleuchtet. Ein wesentlicher Teil war auch die Homogenisierung und Kategorisierung der Ergebnisse aus den Erhebungen, um in weiterer Folge Performance‐Indikatoren zu identifizieren und diese dann sogenannten Key‐Performance‐Indikatoren zuzuordnen. Die Erhebung der Performance‐Indikatoren und die Definition von Key‐Performance‐Indikatoren waren wesentliche Schritte zur Entwicklung einer standardisierten Richtlinie zur Erstellung von Qualitätskontrollplänen für Straßenbrücken auf europäischer Ebene.
Impact of bistrand abasic sites and proximate orientation on DNA global structure and duplex energetics
Authors: Minetti Conceição A. , Sun Jeffrey Y. , Jacobs Daniel P. , Kang Inkoo , Remeta David P. , Breslauer Kenneth J. 
Published: January 2018

AbstractBistrand lesions embedded within a single helical turn of tridecameric deoxyoligonucleotide duplexes represent a model system for exploring the impact of clustered lesions that occur in vivo and pose a significant challenge to cellular repair machineries. Such investigations are essential for understanding the forces that dictate lesion‐induced mutagenesis, carcinogenesis, and cytotoxicity within a context that mimics local helical perturbations caused by an ionizing radiation event. This study characterizes the structural and energy profiles of DNA duplexes harboring synthetic abasic sites (tetrahydrofuran, F) as models of clustered bistrand abasic (AP) lesions. The standard tridecameric dGCGTACCCATGCG·dCGCATGGGTACGC duplex is employed to investigate the energetic impact of single and bistrand AP sites by strategically replacing one or two bases within the central CCC/GGG triplet. Our combined analysis of temperature‐dependent UV and circular dichroism (CD) profiles reveals that the proximity and relative orientation of AP sites within bistrand‐damaged duplexes imparts a significant thermodynamic impact. Specifically, 3′‐staggered lesions (CCF/GFG) exert a greater destabilizing effect when compared with their 5′‐counterpart (FCC/GFG). Moreover, a duplex harboring the central bistrand AP lesion (CFC/GFG) is moderately destabilized yet exhibits distinct properties relative to both the 3′ and 5′‐orientations. Collectively, our energetic data are consistent with structural studies on bistrand AP‐duplexes of similar sequence in which a 3′‐staggered lesion exerts the greatest perturbation, a finding that provides significant insight regarding the impact of orientation on lesion repair processing efficiency.
Stenting of the inter‐atrial septum in infants and small children: Indications, techniques and outcomes
Authors: Mainzer Gur , Goreczny Sebastian , Morgan Gareth J. , Qureshi Shakeel , Krasemann Thomas , Dryzek Pawel , Moll Jadwiga A , Moszura Tomasz , Rosenthal Eric 
Published: January 2018

AbstractObjectivesTo evaluate the procedural success and outcome of inter‐atrial stenting.BackgroundInter‐atrial stenting has been shown to be an effective way to maintain inter‐atrial blood flow, however it is considered a high risk procedure, usually performed urgently in patients with significant hemodynamic compromise.MethodsBetween September 2004 and August 2016, inter‐atrial stenting was attempted in 29 children. Procedural, clinical, and follow‐up data were collected retrospectively.ResultsThe procedures were completed successfully in 27 patients. Twenty‐five procedures were undertaken percutaneously, with the remaining four being performed as hybrid procedures. The patients were considered as high risk for adverse events (82% scored as CRISP 4 and 5) with four deaths during the first 24 hr (14%). Procedural complications occurred in eight patients (28%) with related death in three patients (10%). One further patient died after an uncomplicated technically successful stent implantation performed as a salvage procedure. Procedural complications (71% vs. 14%) and mortality (43% vs. 5%) were higher in those, who weighed 3 kg or less (P < 0.05). Patency of the stents was maintained until planned staged surgery in 22 patients at a mean of 302 days. Three patients underwent further balloon dilation for flow restriction at 58–201 days. In two un‐operated patients the stents remained patent at follow‐up. One patient with severe pulmonary hypertension died with a patent stent.ConclusionsInter‐atrial stenting produces reliable patency with a very good success rate. Morbidity and mortality were related to low weight at the time of the procedure.
Validation of contemporary risk scores in predicting coronary thrombotic events and major bleeding in patients with acute coronary syndrome after drug‐eluting stent implantations
Authors: Song Li , Guan Changdong , Yan Hongbing , Qiao Shubin , Wu Yongjian , Yuan Jinqing , Dou Kefei , Yang Yuejin , Dangas George D. , Xu Bo 
Published: January 2018

AbstractObjectivesWe aimed to assess the prognostic ability of the ST score, DAPT score, and PARIS score in a Chinese population.BackgroundRecently, several risk scores predicting the long‐term risk of coronary thrombotic events [CTE, defined as the composite of definite or probable stent thrombosis (ST) and myocardial infarction] and bleeding have been developed and initially validated in Western populations.MethodsA total of 6,088 consecutive patients with acute coronary syndrome (mean age 58.3 ± 10.4; women 23.1%) treated with drug‐eluting stents in 2013 at our single institution were enrolled. We calculated risk scores and evaluated their performance for predicting definite or probable ST, CTE and major bleeding (MB, defined as the occurrence of a Bleeding Academic Research Consortium type 3 or 5 bleed). The prognostic value of risk scores was assessed by receiver‐operating characteristic curves.ResultsThe ST score, DAPT score, and PARIS score all showed unsatisfactory discrimination to predict 2‐year or 1‐ to 2‐year ST and CTE (c‐statistic = 0.51–0.59). With respect to bleeding outcomes, the PARIS score showed unsatisfactory discrimination in predicting 2‐year MB (c‐statistic = 0.56); the DAPT score performed slightly better than the PARIS score in predicting occurrence of later MB events between 1 and 2 years, whereas its discriminative capacity was only modest (c‐statistic = 0.71).ConclusionsThe current three risk scores, derived and initially validated in Western populations, may not be applicable to the Chinese population, although DAPT score was determined to be a modestly accurate quantitative tool for prediction of later MB.
Methanation of Carbon Dioxide over Zeolite‐Encapsulated Nickel Nanoparticles
Authors: Goodarzi Farnoosh , Kang Liqun , Wang Feng Ryan , Joensen Finn , Kegnæs Søren , Mielby Jerrik 
Published: January 2018

AbstractEfficient methanation of CO2 relies on the development of more selective and stable heterogeneous catalysts. Herein, we present a simple and effective method to encapsulate Ni nanoparticles in zeolite silicalite‐1. In this method, the zeolite is modified by selective desilication, which creates intraparticle voids and mesopores that facilitate the formation of small and well‐dispersed nanoparticles upon impregnation and reduction. Transmission electron microscopy and X‐ray photoelectron spectroscopy analyses confirm that a significant part of the Ni nanoparticles are situated inside the zeolite rather than on the outer surface. The encapsulation results in increased metal dispersion and, consequently, high catalytic activity for CO2 methanation. With a gas hourly space velocity of 60 000 mL gcatalyst−1 h−1 and H2/CO2=4, the zeolite‐encapsulated Ni nanoparticles result in 60 % conversion at 450 °C, which corresponds to a site‐time yield of approximately 304 mol
molNi−1 h−1. The encapsulated Ni nanoparticles show no change in activity or selectivity after 50 h of operation, although postcatalysis characterization reveals some particle migration.
Volumetric Heat Transfer Coefficient in Fluidized‐Bed Dryers
Authors: Poós Tibor , Szabó Viktor 
Published: January 2018

AbstractIn literature, there are several Nu=f(Re) equations to specify the heat transfer coefficient between solids and the drying gas, but these equations differ significantly because of the inaccuracy of determining the contact surface between the two phases. A pilot‐plant fluidized‐bed dryer is developed to study the heat and mass transfer phenomena during the drying process. A volumetric heat transfer coefficient is applied for modeling fluidized‐bed dryers. A modified Nusselt number is defined to compare the experimental results and those of the literature. The modified Nu'=f(Re) equation exhibits a proper correlation between the results of the experiments in the literature and those of our experiments.