bluuebunny/crossref_metadata_2025_split huggingface dataset:
Business Models for Cultural Heritage Adaptive Reuse
Authors: Vellecco Immacolata , Martone Assunta 
Published: October 2024

AbstractLiterature on business models is a pillar of management research and its recent contributions have broadened traditional frameworks to include sustainability and circular economy issues. However, contributions focused on business models of cultural heritage have always been scarce; moreover, most of the studies on adaptive reuse of cultural heritage are based on the analysis of individual assets. A few studies make in-depth analysis of the business model and they hardly produce generalizable results, due to the idiosyncratic nature of cultural heritage and its link with the cultural, social, environmental and economic context, that makes it difficult to replicate the process and decisions of reuse (in structural and managerial terms).
Heritage-Led Entrepreneurial Ecosystems: Skills and Role of Startups and Innovation
Authors: Gravagnuolo Antonia , Lupu Aliona , Stanojev Jermina , Catanese Valeria 
Published: October 2024

AbstractCultural heritage is recognized as a powerful driver of sustainable development in cities and regions. The adaptive reuse and regeneration of cultural and natural heritage can become a driver of jobs creation, as demonstrated by many experiences. At the same time, cultural heritage adaptive reuse can involve communities in innovative and unexpected ways, generating multiple positive impacts in the territories and boosting a more sustainable, resilient, and equitable development model to finally create cities of opportunities connecting culture and innovation. This chapter aims to share the experience of the Horizon 2020 CLIC project in developing innovative circular business models for cultural heritage adaptive reuse, through the selection and training of start-ups during the entrepreneurial event of the CLIC Startup Competition in 2020 and subsequent mentoring programme. The chapter presents virtuous case studies as examples of successful social entrepreneurship and circular business model of heritage reuse and regeneration. A critical reflection on the role of social entrepreneurship and innovative business models for circular cultural heritage adaptive reuse is provided based on the experience of the project.
Understanding Best Practices of Cultural Heritage Adaptive Reuse in the Perspective of the Circular Economy: In-Depth Assessment of Case Studies
Authors: Buglione Francesca , Gravagnuolo Antonia , Angrisano Mariarosaria , Iodice Silvia , Bosone Martina , De Toro Pasquale , Fusco Girard Luigi 
Published: October 2024

AbstractThe CLIC adaptive reuse of cultural heritage argued that cultural heritage adaptive reuse can represent a viable strategy for the implementation of circular cities and regions, contributing to the reuse of natural and cultural resources, the re-generation of values of heritage sites and buildings, and in many cases also to social and community bonds regeneration thanks to new social uses of heritage sites. In the first phase of the adaptive reuse of cultural heritage, the theoretical circular model of cultural heritage adaptive reuse was developed applying inter-disciplinary and trans-disciplinary approaches involving adaptive reuse of cultural heritage and practitioners from diverse fields in a common reflection. The circular model was discussed, and further explored through the analysis of cultural heritage adaptive reuse practices, applying statistical analysis tools to identify the “best practices” in the perspective of circularity. The experiences analysed were not meant initially to reach specific circularity goals, and therefore they do not represent yet “ideal” solutions for circular adaptive reuse of cultural heritage. However, relevant lessons can be learnt from these practices, that can be applied in the design and implementation of future circular solutions for abandoned and underused cultural heritage.
The CLIC Multidimensional Impacts Assessment Framework: Criteria and Indicators for Circular “Human-Centred” Adaptive Reuse of Cultural Heritage
Authors: Gravagnuolo Antonia , Bosone Martina , Fusco Girard Luigi 
Published: October 2024

AbstractHeritage is present in everyday society and it is a resource linked to social capital, economic growth, and environmental sustainability (Bandarin and van Oers 2014). Adaptive reuse is defined as “any building work and intervention aimed at changing its capacity, function or performance to adjust, reuse or upgrade a building to suit new conditions or requirements” (Douglas 2006). In Historic Preservation: Curatorial Management of the Built World (1982), James Marston Fitch points out that the adaptive reuse of historic buildings “is more economic” not only in terms of the “conservation of the energy represented by the built environment,” but also for the “relative costs of old and new built space”. Adaptive reuse can be an effective conservation strategy allowing present and future use of abandoned heritage buildings, groups of buildings, landscapes or sites, changing and enhancing their functions and adapting the existing features to new needs (Bullen and Love 2010). However, the adaptive reuse intervention should not compromise heritage values, thus the threshold of transformation versus conservation should be carefully identified. Cultural heritage adaptive reuse is a complex activity, where multiple and often conflicting values need to be considered (CHCfE consortium 2015). Therefore, adaptive reuse should be supported by adequate multidimensional and multicriteria evaluation tools which enable to deal with multiple values and needs, also considering the diverse range of stakeholders, users and beneficiaries of the interventions This study presents the structured framework for the ex-post and ex-ante evaluation of the impacts of cultural heritage adaptive reuse practices in the perspective of the circular economy. It builds on previous analysis of more than 120 case studies of cultural heritage adaptive reuse. The aim of this chapter is to identify multidimensional evaluation tools, as criteria and indicators, according to the CLIC framework of circular adaptive reuse of cultural heritage, starting from the analysis of previous studies and ex-post evaluation of adaptive reuse practices, to structure a comprehensive operational framework for ex-ante evaluation and participatory decision-support in the perspective of circularity.
A New Approach to Universal F-inverse Monoids in Enriched Signature
Authors: Kudryavtseva Ganna , Lemut Furlani Ajda 
Published: October 2024

AbstractWe show that the universal X-generated F-inverse monoid F(G), where G is an X-generated group, introduced by Auinger, Szendrei and the first-named author, arises as a quotient inverse monoid of the Margolis-Meakin expansion $$M(G, X\cup {\overline{G}})$$

M
(
G
,
X
∪

G
¯

)

of G, with respect to the extended generating set $$X\cup {\overline{G}}$$

X
∪

G
¯

, where $${\overline{G}}$$

G
¯

is a bijective copy of G which encodes the m-operation in F(G). The construction relies on a certain dual-closure operator on the semilattice of all finite and connected subgraphs containing the origin of the Cayley graph $${\text {Cay}}(G, X\cup {{\overline{G}}})$$

Cay
(
G
,
X
∪

G
¯

)

and leads to a new and simpler proof of the universal property of F(G).
Wood treatment by inorganic alumino-silicate polymers
Authors: Barbero-López Aitor , Kinnunen Paivo , Haapala Antti 
Published: October 2024

AbstractThis work assesses the effectiveness of dilute inorganic alumino-silicate polymer suspensions in enhancing wood’s durability, fire resistance, and mechanical properties. Alumino-silicate polymer-treated wood exposed to Coniophora puteana lost less than 3% mass on average, compared to 20% for controls. The moduli of elasticity and rupture of treated specimens were nearly twice as high as those of the controls. Coating with the inorganic polymer was also effective as a fire retardant. Results indicate that inorganic alumino-silicate polymers are a very promising wood treatment.
Chalcopyrite, sphalerite, and pyrite chemistry in stratiform sediment-hosted Cu(-Co) metallogenic districts: trace element characteristics and factors controlling polymetallic mineralization
Authors: Bertrandsson Erlandsson Viktor , Foltyn Krzysztof , Muchez Philippe , Rantitsch Gerd , Ellmies Rainer , Melcher Frank 
Published: October 2024

AbstractStratiform sediment-hosted Cu deposits are significant global sources of Cu and other important metals. The Polish Kupferschiefer produces Ag, Au, Pb, Ni, Se, and Re as by-products, whereas Co is one the of most important metals in the stratiform sediment-hosted Cu-Co deposits of the Central African Copperbelt and the Namibian Dolostone Ore Formation deposit. This study combines new and published laser ablation inductively coupled plasma mass spectrometry sulfide trace element data from these stratiform sediment-hosted copper districts. All the investigated districts exhibit sulfides occurring as disseminations and within later veins. Chalcopyrite, sphalerite, and pyrite trace element contents vary significantly between the metallogenic districts as well as between different ore stages. Random Forest discriminates the stratiform sediment-hosted Cu(-Co) districts based on trace element geochemistry. High Ag and Tl in chalcopyrite is attributed to the Polish Kupferschiefer, Ga and Ge to the Katanga Copperbelt, and Zn and In to the Dolostone Ore Formation deposit. Sphalerite from the Polish Kupferschiefer and the Dolostone Ore Formation deposit can be distinguished on the basis of the Fe and Cd contents. Cobalt and As are significantly elevated in pyrite from the Katanga Copperbelt and Mn in pyrite from the Dolostone Ore Formation deposit. The trace element contents also show that the stratiform sediment-hosted Cu(-Co) deposit sulfide data cluster separately from other deposit types. The variation in sulfide trace element contents between the three investigated stratiform sediment-hosted Cu(-Co) districts suggests that sulfide chemistry is related to the geology of the host basin and the nature of the underlying basement, which includes preexisting ore occurrences.
Classification, angioarchitecture and treatment outcomes of medullary bridging vein-draining dural arteriovenous fistulas in the foramen magnum region: a multicenter study
Authors: Ozaki Tomohiko , Hiramatsu Masafumi , Nakamura Hajime , Niimi Yasunari , Tanoue Shuichi , Mizutani Katsuhiro , Nakahara Ichiro , Matsumaru Yuji , Matsumoto Yasushi , Krings Timo , Fujinaka Toshiyuki 
Published: October 2024

Abstract

Purpose
This study aimed to classify medullary bridging vein-draining dural arteriovenous fistulas (MBV-DAVFs) located around the foramen magnum (FM) according to their location and characterize their angioarchitecture and treatment outcomes.

Methods
Patients with MBV-DAVFs diagnosed between January 2013 and October 2022 were included. MBV-DAVFs were classified into four groups. Jugular vein-bridging vein (JV-BV) DAVF: located in proximity to jugular fossa, Anterior condylar vein (ACV)-BV DAVF: proximity to anterior condylar canal, Marginal sinus (MS)-BV DAVF: lateral surface of FM and Suboccipital cavernous sinus (SCS)-BV DAVF: proximity to dural penetration of vertebral artery.

Results
Twenty patients were included, three JV-BV, four ACV-BV, three MS-BV and ten SCS-BV DAVFs, respectively. All groups showed male predominance. There were significant differences in main feeders between JV (jugular branch of ascending pharyngeal artery) and SCS group (C1 dural branch). Pial feeders from anterior spinal artery (ASA) or lateral spinal artery (LSA) were visualized in four SCS and one MS group. Drainage pattern did not differ between groups. Transarterial embolization (TAE) was performed in three, two, one and two cases and complete obliteration was obtained in 100%, 50%, 100% and 0% in JV, ACS, MS and SCS group, respectively. Successful interventions without major complications were finally obtained in 100%, 75%, 100%, and 40% in JV, ACS, MS and SCS group, respectively.

Conclusion
JV-BV DAVFs were successfully treated using TAE alone. SCS-BV DAVFs were mainly fed by small C1 dural branches of vertebral artery often with pial feeders from ASA or LSA, and difficultly treated by TAE alone.
Elevated Trans-mitral Pressure Gradient Predicts Surgery in Young People with Moderate–Severe Rheumatic Mitral Regurgitation
Authors: Williamson Jacqueline M. , Whalley Gillian A. , Horton Ari E. , Morris Peter , Remenyi Bo 
Published: October 2024

AbstractMitral regurgitation (MR) is the most common lesion in children with rheumatic heart disease (RHD). Progression of RHD results in the need for surgical intervention, the timing of which is dictated by left ventricular dilatation and the onset of heart failure symptoms. We sought to determine whether elevation in trans-mitral pressure gradient (TMPG) in those with moderate or severe rheumatic MR without significant mitral stenosis (MS) could predict the need for future surgical intervention. Echocardiographic studies were reviewed for 116 children and young people with moderate or severe rheumatic MR. Those with significant mitral stenosis or concurrent aortic valve disease were excluded. Trans-mitral pressure gradient was measured at baseline and details of mitral valve surgical intervention were retrieved from a registry database. Time to future surgery (up to six years) was compared between those with TMPG < 5 mmHg and TMPG ≥ 5 mmHg. Survival curves demonstrated an increased risk of surgery for those with TMPG ≥ 5 mmHg with Cox proportional regression analysis providing a hazard ratio of 5.8. The proportion free from mitral valve surgery at one year for the TMPG < 5 mmHg group was 0.94 (95% CI 0.86–0.97), compared to 0.62 (95% CI 0.42–0.77) in the ≥ 5 mmHg group. Trans-mitral pressure gradient is a strong predictor of future mitral valve surgery in children and young people with significant rheumatic MR without MS. This non-invasive measure could be used to signal the need for more aggressive monitoring in order to optimize the timing of intervention.
Retinal oxygen metabolic function in choroideremia and retinitis pigmentosa
Authors: Prétot Dominique , della Volpe Waizel Maria , Kaminska Karolina , Valmaggia Philippe , Placidi Giorgio , Falsini Benedetto , Fries Fabian N. , Szentmáry Nóra , Rivolta Carlo , Scholl Hendrik P. N. , Calzetti Giacomo 
Published: October 2024

Abstract
Purpose
To measure the retinal oxygen metabolic function with retinal oximetry (RO) in patients with choroideremia (CHM) and compare these findings with retinitis pigmentosa (RP) patients and controls.

Methods
Prospective observational study including 18 eyes of 9 molecularly confirmed CHM patients (9♂; 40.2 ± 21.2 years (mean ± SD), 77 eyes from 39 patients with RP (15♀ 24♂; 45.6 ± 14.7 years) and 100 eyes from 53 controls (31♀ 22♂; 40.2 ± 13.4 years). Main outcome parameters were the mean arterial (A-SO2; %), venular (V-SO2; %) oxygen saturation, and their difference (A-V SO2; %) recorded with the oxygen saturation tool of the Retinal Vessel Analyzer (IMEDOS Systems UG, Germany). Statistical analyses were performed with linear mixed-effects models.

Results
Eyes suffering from CHM differed significantly from both RP and control eyes, when the retinal oxygen metabolic parameters were taken into account. While RP showed significantly higher A-SO2 and V-SO2 values when compared to controls, CHM showed opposite findings with significantly lower values when compared to both RP and controls (P < 0.001). The A-V SO2, which represents the retinal oxygen metabolic consumption, showed significantly lower values in CHM compared to controls.

Conclusion
The retina in CHM is a relatively hypoxic environment. The decrease in oxygen levels may be due to the profound choroidal degeneration, leading to decreased oxygen flux to the retina. RO measurements may help understand the pathogenesis of CHM and RP. These findings may provide useful details to inform the planning of clinical trials of emerging therapies for CHM.

Key messages
What was known before?

Retinal oxygen metabolic function measured with retinal oximetry (RO) shows significant alterations in patients with retinitis pigmentosa.

What this study adds:

RO function in choroideremia is significantly altered when compared to controls.

Furthermore, RO in choroideremia shows opposing findings within different oxygen metabolic parameters to those that were so far known for retinitis pigmentosa.

By providing insights into the retinal oxygen metabolic mechanisms, RO can help understand the underlying pathophysiology in choroideremia.
Mises-Fisher similarity-based boosted additive angular margin loss for breast cancer classification
Authors: Alirezazadeh P. , Dornaika F. , Charafeddine J. 
Published: October 2024

AbstractTo enhance the accuracy of breast cancer diagnosis, current practices rely on biopsies and microscopic examinations. However, this approach is known for being time-consuming, tedious, and costly. While convolutional neural networks (CNNs) have shown promise for their efficiency and high accuracy, training them effectively becomes challenging in real-world learning scenarios such as class imbalance, small-scale datasets, and label noises. Angular margin-based softmax losses, which concentrate on the angle between features and classifiers embedded in cosine similarity at the classification layer, aim to regulate feature representation learning. Nevertheless, the cosine similarity’s lack of a heavy tail impedes its ability to compactly regulate intra-class feature distribution, limiting generalization performance. Moreover, these losses are constrained to target classes when margin penalties are applied, which may not always optimize effectiveness. Addressing these hurdles, we introduce an innovative approach termed MF-BAM (Mises-Fisher Similarity-based Boosted Additive Angular Margin Loss), which extends beyond traditional cosine similarity and is anchored in the von Mises-Fisher distribution. MF-BAM not only penalizes the angle between deep features and their corresponding target class weights but also considers angles between deep features and weights associated with non-target classes. Through extensive experimentation on the BreaKHis dataset, MF-BAM achieves outstanding accuracies of 99.92%, 99.96%, 100.00%, and 98.05% for magnification levels of ×40, ×100, ×200, and ×400, respectively. Furthermore, additional experiments conducted on the BACH dataset for breast cancer classification, as well as on the LFW and YTF datasets for face recognition, affirm the generalization capability of our proposed loss function.
Snow leopard phylogeography and population structure supports two global populations with single refugial origin
Authors: Cancellare Imogene A. , Weckworth Byron , Caragiulo Anthony , Pilgrim Kristine L. , McCarthy Thomas M. , Abdullaev Alisher , Amato George , Bian Xiaoxing , Bykova Elena , Dias-Freedman Isabela , Gritsina Mariya , Hennelly Lauren M. , Janjua Safia , Johansson Orjan , Kachel Shannon , Karnaukhov Alexander , Korablev Miroslav , Kubanychbekov Zairbek , Kulenbekov Rahim , Liang Xuchang , Lkhagvajav Purevjav , Meyer Tara K. , Munkhtsog Bariushaa , Munkhtsog Bayaraa , Nawaz Muhammad A. , Ostrowski Stephane , Paltsyn Mikhail , Poyarkov Andrey , Rabinowitz Salisa , Rooney Thomas , Rosen Tatjana , Rozhnov Viatcheslav V. , Sacks Benjamin N. , Schwartz Michael K. , McCarthy Kyle P. 
Published: October 2024

AbstractSnow leopards (Panthera uncia) inhabit the mountainous regions of High Asia, which experienced serial glacial contraction and expansion during climatic cycles of the Pleistocene. The corresponding impacts of glacial vicariance may have alternately promoted or constrained genetic differentiation to shape the distribution of genetic lineages and population structure. We studied snow leopard phylogeography across High Asia by examining range-wide historical and contemporary genetic structure with mitochondrial DNA and microsatellite markers. We genotyped 182 individuals from across snow leopard range and sequenced portions of the mitogenome in a spatially stratified subset of 80 individuals to infer historical biogeographic and contemporary patterns of genetic diversity. We observed a lack of phylogeographic structure, and analyses suggested a single refugial origin for all sampled populations. Molecular data provided tentative evidence of a hypothesized glacial refugia in the Tian Shan-Pamir-Hindu Kush-Karakoram mountain ranges, and detected mixed signatures of population expansion. Concordant assessments of microsatellite data indicated two global genetic populations, though we detected geographic differences between historical and contemporary population structure and connectivity inferred from mitochondrial and microsatellite data, respectively. Using the largest sample size and geographic coverage to date, we demonstrate novel information on the phylogeographic history of snow leopards, and corroborate existing interpretations of snow leopard connectivity and genetic structure. We recommend that conservation efforts incorporate genetic data to define and protect meaningful conservation units and their underlying genetic diversity, and to maintain the snow leopard’s adaptive potential and continued resilience to environmental changes.
From greatest simplicity to full power
Authors: Gomes Luís , Branco António , Silva João , Branco Ruben 
Published: October 2024

AbstractWhile language processing services are key assets for the science and technology of language, the possible ways under which they may be made available to the widest range of their end users are critical to support an Open Science policy for this scientific domain. Although providing such processing services under some web-based interface, at large, offers itself as an immediate and cogent response to that challenge, turning this view into an effective access to language processing services is an undertaking deserving a clear conceptual direction and a corresponding robust empirical validation. Based on an extensive overview of major undertakings towards making language processing tools available and on the design principles worked out and implemented in the PORTULAN CLARIN infrastructure, in this paper we advocate for a Research-Infrastructure-as-a-Service (RIaaS) model. This model unleashes accessibility to language processing services in as many web-based interface modalities as the current stage of technological development permits to support, in order to serve as many types of end users as possible, from IT developers to Digital Humanities researchers, and including citizen scientists, teachers, students and digital artists among many others.
Appreciating dyslexic thinking in qualitative research: reflections and recommendations for culturally competent, neuro-inclusive academia
Authors: Ademolu Edward 
Published: October 2024

AbstractDyslexia and its associated learning challenges are often misconstrued as intellectual deficits, leading to erroneous assumptions that individuals with dyslexia cannot thrive or contribute meaningfully to academic institutions. However, this article contends that the unique thinking patterns associated with dyslexia are complementary to and can substantially enrich the professional practice of qualitative research. The social model of disability emphasises how Higher Education Institutions, rooted in ableist and neurotypical norms, often marginalise and fail to accommodate dyslexic cognitive profiles. Conversely, cultural competency, as an actionable conceptual framework, calls for transformative changes that promote understanding, build meaningful relationships, and ensure effective communication with neurodivergent individuals. Drawing on my experience as a dyslexic academic, I examine critical discussions on disability, neurodiversity, higher education, and qualitative research. Adopting an autoethnographic methodological approach, I highlight my professional strengths within this context, and propose an adaptable cultural competency framework aimed at cultivating neuro-inclusive—and specifically dyslexic-friendly practices, at the individual and organisational levels within academia.