bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women have a worse prognosis and undergo fewer coronary angiographies after out-of-hospital cardiac arrest than men
Authors: Winther-Jensen Matilde , Hassager Christian , Kjaergaard Jesper , Bro-Jeppesen John , Thomsen Jakob H , Lippert Freddy K , Køber Lars , Wanscher Michael , Søholm Helle 
Published: February 2017

Background: Out-of-hospital cardiac arrest is more often reported in men than in women. Objectives: We aimed to assess sex-related differences in post-resuscitation care; especially with regards to coronary angiography, percutaneous coronary intervention, mortality and functional status after out-of-hospital cardiac arrest. Methods: We included 704 consecutive adult out-of-hospital cardiac arrest-patients with cardiac aetiology in the Copenhagen area from 2007–2011. Utstein guidelines were used for the pre-hospital data. Vital status and pre-arrest comorbidities were acquired from Danish registries and review of patient charts. Logistic regression was used to assess differences in functional status and use of post-resuscitation care. Cox regression was used to assess differences in 30-day mortality. We used ‘smcfcs’ and ‘mice’ imputation to handle missing data. Results: Female sex was associated with higher 30-day mortality after adjusting for age and comorbidity (hazard ratio (HR): 1.42, confidence interval (CI): 1.13–1.79, p<0.01), this was not significant when adjusting for primary rhythm (HR: 1.12, CI: 0.88–1.42, p=0.37). Women less frequently received coronary angiography <24 h in multiple regression after out-of-hospital cardiac arrest (odds ratio (OR)CAG=0.55, CI: 0.31–0.97, p=0.041), however no difference in percutaneous coronary intervention was found (ORPCI=0.55, CI: 0.23–1.36, p=0.19). Coronary artery bypass grafting was less often performed in women (ORCABG: 0.10, CI: 0.01–0.78, p=0.03). There was no difference in functional status at discharge between men and women ( p=1). Conclusion: Female sex was not significantly associated with higher mortality when adjusting for confounders. Women less often underwent coronary angiography and coronary artery bypass grafting, but it is not clear whether this difference can be explained by other factors, or an actual under-treatment in women.
Intermediate- to Long-Term Results of Combined Anterior Cruciate Ligament Reconstruction and Autologous Chondrocyte Implantation
Authors: Pike Andrew N. , Bryant Tim , Ogura Takahiro , Minas Tom 
Published: February 2017

Background: Cartilage injury associated with anterior cruciate ligament (ACL) ruptures is common; however, relatively few reports exist on concurrent cartilage repair with ACL reconstruction. Autologous chondrocyte implantation (ACI) has been utilized successfully for treatment of moderate to large chondral defects. Hypothesis: ACL insufficiency with relatively large chondral defects may be effectively managed with concurrent ACL reconstruction and ACI. Study Design: Case series; Level of evidence, 4. Methods: Patients undergoing concurrent ACL primary or revision reconstruction with ACI of single or multiple cartilage defects were prospectively evaluated for a minimum 2 years. Pre- and postoperative outcome measures included the modified Cincinnati Rating Scale (MCRS), Western Ontario and McMaster Universities Osteoarthritis Index, visual analog pain scales, and postsurgery satisfaction surveys. ACI graft failure or persistent pain without functional improvement were considered treatment failures. Results: Twenty-six patients were included, with 13 primary and 13 revision ACL reconstructions performed. Mean defect total surface area was 8.4 cm2, with a mean follow-up of 95 months (range, 24-240 months). MCRS improved from 3.62 ± 1.42 to 5.54 ± 2.32, Western Ontario and McMaster Universities Osteoarthritis Index from 45.31 ± 17.27 to 26.54 ± 17.71, and visual analog pain scale from 6.19 ± 1.27 to 3.65 ± 1.77 (all Ps <.001). Eight patients were clinical failures, 69% of patients were improved at final follow-up, and 92% stated they would likely undergo the procedure again. No outcome correlation was found with regard to age, body mass index, sex, defect size/number, follow-up time, or primary versus revision ACL reconstruction. In subanalysis, revision ACL reconstructions had worse preoperative MCRS scores and greater defect surface areas. However, revision MCRS score improvements were greater, resulting in similar final functional scores when compared with primary reconstructions. Conclusion: Challenging cases of ACL tears with large chondral defects treated with concurrent ACL reconstruction and ACI can lead to moderately improved pain and function at long-term follow-up. Factors associated with clinical failure are not clear. When combined with ACI, patients undergoing revision ACL reconstructions have worse function preoperatively compared with those undergoing primary reconstructions but have similar final outcomes.
How Can Home Care Patients and Their Caregivers Better Manage Fall Risks by Leveraging Information Technology?
Authors: Alhuwail Dari , Koru Güneş , Nahm Eun-Shim 
Published: February 2017

Objectives: From the perspectives of home care patients and caregivers, this study aimed to (a) identify the challenges for better fall-risk management during home care episodes and (b) explore the opportunities for them to leverage health information technology (IT) solutions to improve fall-risk management during home care episodes. Methods: Twelve in-depth semistructured interviews with the patients and caregivers were conducted within a descriptive single case study design in 1 home health agency (HHA) in the mid-Atlantic region of the United States. Results: Patients and caregivers faced challenges to manage fall risks such as unmanaged expectations, deteriorating cognitive abilities, and poor care coordination between the HHA and physician practices. Opportunities to leverage health IT solutions included patient portals, telehealth, and medication reminder apps on smartphones. Conclusion: Effectively leveraging health IT could further empower patients and caregivers to reduce fall risks by acquiring the necessary information and following clinical advice and recommendations. The HHAs could improve the quality of care by adopting IT solutions that show more promise of improving the experiences of patients and caregivers in fall-risk management.
Estimating the prevalence of dementia using multiple linked administrative health records and capture–recapture methodology
Authors: Waller Michael , Mishra Gita D. , Dobson Annette J. 
Published: February 2017

Abstract
Background
Obtaining population-level estimates of the incidence and prevalence of dementia is challenging due to under-diagnosis and under-reporting. We investigated the feasibility of using multiple linked datasets and capture–recapture techniques to estimate rates of dementia among women in Australia.

Methods
This work is based on the Australian Longitudinal Study on Women’s Health. A random sample of 12,432 women born in 1921–1926 was recruited in 1996. Over 16 years of follow-up records of dementia were obtained from five sources: three-yearly self-reported surveys; clinical assessments for aged care assistance; death certificates; pharmaceutical prescriptions filled; and, in three Australian States only, hospital in-patient records.

Results
A total of 2534 women had a record of dementia in at least one of the data sources. The aged care assessments included dementia records for 79.3% of these women, while pharmaceutical data included 34.6%, death certificates 31.0% and survey data 18.5%. In the States where hospital data were available this source included dementia records for 55.8% of the women. Using capture–recapture methods we estimated an additional 728 women with dementia had not been identified, increasing the 16 year prevalence for the cohort from 20.4 to 26.0% (95% confidence interval [CI] 25.2, 26.8%).

Conclusions
This study demonstrates that using routinely collected health data with record linkage and capture–recapture can produce plausible estimates for dementia prevalence and incidence at a population level.
Securing an OTL-HNS residency: How competitive is it? Comparing medical student perceptions to actual Canadian statistics
Authors: Kay-Rivest E. , Varma N. , Scott G. M. , Manoukian J. J. , Desrosiers M. , Vaccani J. P. , Nguyen L. H. P. 
Published: February 2017

Background The residency match is an important event in an aspiring physician's career. Otolaryngology – Head and Neck Surgery (OTL-HNS) is a surgical specialty that has enjoyed high numbers of applicants to its residency programs. However, recent trends in Canada show a decline in first-choice applicants to several surgical fields. Factors thought to influence a medical student's choice include role models, career opportunities and work-life balance. The notion of perceived competitiveness is a factor that has not yet been explored. This study sought to compare competitiveness of OTL-HNS, as perceived by Canadian medical students to residency match statistics published yearly by CaRMS (Canadian Residency Matching Service), with the hope of informing future decisions of surgical residency programs. Methods An electronic survey was created and distributed to all medical students enrolled in the 17 Canadian medical schools. After gathering demographic information, students were asked to rank what they perceived to be the five most competitive disciplines offered by CaRMS. They were also asked to rank surgical specialties from most to least competitive. Publically available data from CaRMS was then collected and analyzed to determine actual competitiveness of admissions to Canadian OTL-HNS residency programs. Results 1194 students, from first to fourth year of medical school, completed the survey. CaRMS statistics over the period from 2008 to 2014 demonstrated that the five most competitive specialties were Plastic Surgery, Dermatology, Ophthalmology, Emergency Medicine and OTL-HNS. Among surgical disciplines, OTL-HNS was third most competitive, where on average 72% of students match to their first-choice discipline. When students were questioned, 35% ranked OTL-HNS amongst the top five most competitive. On the other hand 72%, 74% and 80% recognized Opthalmology, Dermatology and Plastic Surgery as being among the five most competitive, respectively. We found that fourth-year medical students were significantly more knowledgeable about the competitiveness of both OTL-HNS and Plastic Surgery compared to first-year students ( p < 0.01). Conclusion Overall, Canadian medical students may underestimate the competitiveness of OTL-HNS. Furthermore, competitiveness would appear to be a concept that resonates with medical students during the match process.
Analyzing chemical changes in verdigris pictorial specimens upon bacteria and fungi biodeterioration using voltammetry of microparticles
Authors: Ortiz-Miranda Annette S. , Doménech-Carbó Antonio , Doménech-Carbó María Teresa , Osete-Cortina Laura , Bolívar-Galiano Fernando , Martín-Sánchez Inés 
Published: February 2017

Abstract
It is reported the application of the voltammetry of microparticles (VMP), complemented with attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) and field emission scanning electron microscopy (FESEM) techniques, to monitor the deterioration of verdigris pictorial specimens under the action of different biological agents. This methodology would be of application for identifying the type of biological agent causing deterioration of paintings, which is an important problem affecting cultural heritage. The analysis of biodeterioration processes is complicated by the fact that the action of microorganisms can affect both pigment and binding media. The deterioration of pictorial specimens combining verdigris with egg and egg–linseed oil binders by Penicillium chrysogenum, Aspergillus niger, Acremonium chrysogenum, Trychoderma pseudokoningi and Mucor rouxii fungi and Bacillus amyloliquefaciens, Arthrobacter oxydans and Streptomyces cellulofans bacteria were tested using sample-modified graphite electrodes immersed into aqueous electrolytes. A model is presented to describe the involved electrochemistry resulting in specific voltammetric features for the electrochemical reduction of verdigris associated to the proteinaceous and lipidic fractions of the binders. The experimental results and model proposed have been discussed and compared with those previously obtained for cadmium yellow reconstructed paint film specimens.
Multicenter, Phase III, Randomized, Double-Blind, Placebo-Controlled Trial of Pravastatin Added to First-Line Standard Chemotherapy in Small-Cell Lung Cancer (LUNGSTAR)
Authors: Seckl Michael J. , Ottensmeier Christian H. , Cullen Michael , Schmid Peter , Ngai Yenting , Muthukumar Dakshinamoorthy , Thompson Joyce , Harden Susan , Middleton Gary , Fife Kate M. , Crosse Barbara , Taylor Paul , Nash Stephen , Hackshaw Allan 
Published: February 2017

Purpose Treating small-cell lung cancer (SCLC) remains a therapeutic challenge. Experimental studies show that statins exert additive effects with agents, such as cisplatin, to impair tumor growth, and observational studies suggest that statins combined with anticancer therapies delay relapse and prolong life in several cancer types. To our knowledge, we report the first large, randomized, placebo-controlled, double-blind trial of a statin with standard-of-care for patients with cancer, specifically SCLC. Patients and Methods Patients with confirmed SCLC (limited or extensive disease) and performance status 0 to 3 were randomly assigned to receive daily pravastatin 40 mg or placebo, combined with up to six cycles of etoposide plus cisplatin or carboplatin every 3 weeks, until disease progression or intolerable toxicity. Primary end point was overall survival (OS), and secondary end points were progression-free survival (PFS), response rate, and toxicity. Results Eight hundred forty-six patients from 91 United Kingdom hospitals were recruited. The median age of recruited patients was 64 years of age, 43% had limited disease, and 57% had extensive disease. There were 758 deaths and 787 PFS events. No benefit was found for pravastatin, either in all patients or in several subgroups. For pravastatin versus placebo, the 2-year OS rate was 13.2% (95% CI, 10.0 to 16.7) versus 14.1% (95% CI, 10.9 to 17.7), respectively, with a hazard ratio of 1.01 (95% CI, 0.88 to 1.16; P = .90. The median OS was 10.7 months v 10.6 months, respectively. The median PFS was 7.7 months v 7.3 months, respectively. The median OS (pravastatin v placebo) was 14.6 months in both groups for limited disease and 9.1 months versus 8.8 months, respectively, for extensive disease. Adverse events were similar between groups. Conclusion Pravastatin 40 mg combined with standard SCLC therapy, although safe, does not benefit patients. Our conclusions are the same as those found in all four much smaller, randomized, placebo-controlled trials specifically designed to evaluate statin therapy in patients with cancer.
Follicular dynamic and repeatability of follicular wave development in Peranakan Ongole (PO) cattle
Authors: Imron Muhammad , Supriatna Iman , Amrozi . , Setiadi Mohamad Agus 
Published: February 2017

<p class="abstrak2">Superovulation treatment on PO cattle (Bos indicus) was less responsive compared to Bos taurus breed. It might due to the difference of their follicular dynamic. This study was conducted to investigate the follicular dynamics and its repeatability in PO cattle. Follicular dynamics observations conducted on 9 cows trough ultrasound scanning every day. Observations of wave patterns repeatability were performed in 6 cows which its wave pattern already known on the next consecutive IOI. Research result indicated that PO cattle had 3 (66%) and 4-waves (34%) pattern. The first wave of 3 and 4-waves pattern emerged on day -0.4+0.9 and 1.4+1.1 respectively. The second wave of 3 and 4-wave pattern emerged on day 9.8+1.5 and 7.4+1.9 respectively. The pattern of 3 waves has a longer follicle dominant duration (11.6+1.5 day) in the first wave of estrous cycle, compared with 4 waves pattern (10+2.92 and 7+1.00 day respectively). The growth rate of dominant follicle was not different significantly between the 3 and 4-waves pattern (0.87+0.23 and 0.94+0.25 mm/day respectively). Similarly, ovulatory follicle diameter between 3 and 4-waves pattern was also not different significantly (12.24+12.34 and 12.30+12.23 mm respectively). Observation of wave patterns repeatability in 6 PO cows indicated that PO cattle had high repeatability in follicular wave pattern (0.88) and the number of growing follicle was 0.91. This study resulted data for dynamic of follicular development, wave pattern, its repeatability which be expected to design the protocol of superovulation treatment or other reproduction technologies based on follicular dynamic to improve its result in PO cattle.</p><p> </p>
APLIKASI PRINSIP KESANTUNAN OLEH ANAK KETIKA BERARGUMEN DENGAN ORANG TUA: Studi Kasus Tindak Persuasi AP Ketika Permintaanya Ditolak
Authors: Prihantoro Prihantoro 
Published: February 2017

Penelitian ini bertujuan mengungkapkan prinsip kesantunan yang digunakan anak ketika berargumen dengan orang tuanya. Data diperoleh secara purposif pada anak bernama AP yang psikogramnya menunjukan keunggulan dalam ranah logika dan linguistik. Data lisan dikumpulkan dalam rentang waktu satu bulan dengan metode observasi dan difokuskan pada argumentasi AP atas penolakan dari permintaanya. Setelah disortir terdapat 124 penolakan dan 97 kali argumentasi. Prosedur analisis data adalah memadankan tuturan penolakan dengan teori kesantunan dari Leech (1983). Dari hasil analisis, lebih dari 80% argumentasi AP parallel dengan tact maxim. Ini menunjukan bahwa dalam argumentasi persuasifnya, ia berusaha untuk memaksimalkan keuntungan dan meminimalkan kerugian pada orang lain, tidak dirinya sendiri. This study is aimed at describing the application of politeness principle by a child when arguing with her parent. The data is obtained purposively on a 5 years old girl named AP, where her psikogram shows that she excels in logic and linguistic. Speech data is collected within a month by observation method. Data selection shows 124 refusals and 97 arguments. I consulted the data to Leech (1983) politeness principles. It shows that more than 80% of AP’s argumentation complies with tact maxim
WISDOM VALUESIN THE BANJARESE PROVERBS
Authors: Farid Rezqan Noor 
Published: February 2017

This study is aimed to reveal parts of Banjarese proverbs which contain wisdom values, to find kinds of wisdom values represented through the Banjarese proverbs, and to reveal social contexts influencing the producing and interpreting process of the proverbs. The data of this study are gathered and selected from several literatures of Banjarese which are then analyzed using critical linguistics. The results of this study show that the parts which contain the wisdom values of the Banjarese people are the clues of interpretation. The wisdom values are also related to the good and the bad behaviours of Banjarese people. It is also found that Islam, as the religion followed by the majority of the Banjarese people, influences the Banjarese culture and Banjarese proverbs. Studi ini bertujuan untuk mencari tahu bagian mana saja dari peribahasa bahasa Banjar yang mengandung nilai kerarifan, menemukan bentuk nilai kearifan didalamnya, dan mengetahui apakah terdapat suatu konteks social yang mempengaruhi proses pembentukan dan penginterpetasian peribahasa itu sendiri. Data dalam studi ini dirangkum dari beberapa literatur yang ditulis oleh orang Banjar sendiri yang dipilih dengan alasan hanya literatur tersebut lah yang tersedia pada waktu studi ini dibuat. Data tersebut kemudian dianalisa dengan metode linguistic kritis. Studi ini menunjukkan bagian dari peribahasa Banjar yang cenderung mengandung nilai kearifan adalah penanda interpretasi. Hasil studi ini juga menunjukkan nilai kearifan dalam peribahasa Banjar terkait dengan sikap yang tidak patut ditiru dan sikap yang pantas untuk diikuti. Dan diasumsikan juga bahwa agama islam, yang terhitung sebagai agama yang dipeluk mayoritas penduduk Banjar, ternyata memiliki pengaruh terhadap kebudayaan dan peribahasa Banjar.
Cutting export subsidies, cropping domestic production: input-output analysis of the Swiss dairy sector after abolishment of the ‘Chocolate law’ subsidies
Authors: KÂHYA Seyhan , KUHAR Aleš 
Published: February 2017

The `Chocolate law’ in Switzerland enables subsidies for dairy and wheat farmers, bound to the condition that their products are exported after processing (Swiss Federation, 2011). Though the Ministerial Conference of the World Trade Organization has decided in December 2015 that this law has to be abolished by 2021 [WTO, 2015]. Cutting subsidies might lead to a demand shock and consequently a cropped domestic production (Miller and Blair, 1985). We analysed in this study the interdependence of the agro-food sectors by a Leontief input-output model and their linkages to other sectors (Chereny and Watanabe, 1958, Leontief 1986) and additionally, the amount, direction and dispersion of the possible demand shock. Hence, non-meat food processors and dairy processing were determined as key sectors as they have strong linkage effects and are rather concentrated to few sectors. Both sectors rely strongly on the output of the raw milk producers and have few sectors to sell their products. Outside of the cut sectors, these sectors will be challenged the most from this new policy.
Simulation of the remanence influence on the transient states in a single-phase multiwinding transformer
Authors: Wilk Andrzej , Michna Michał 
Published: February 2017

Abstract
This paper presents the mathematical model of a single-phase multi-winding core type transformer taking into account magnetic hysteresis phenomenon based on the feedback Preisach model (FPM). The set of loop differential equations was developed for a K-th winding transformer model where the flux linkages of each winding includes flux Φ common to all windings as a function of magneto motive force Θ of all windings. The first purpose of this paper is to implement a hysteresis nonlinearity involved in the Φ(Θ) function which also accounts residual magnetic flux. The second purpose of this paper is experimental validation of the developed transformer model in a capacitor discharge test and several different values of residual magnetic flux.
Multilevel inverter with optimal THD through the firefly algorithm
Authors: El Mehdi Belkacem Riadh , Benzid Redha , Bouguechal Noureddine 
Published: February 2017

Abstract
Reduction of the Total Harmonic Distortion (THD) in multilevel inverters requires resolution of complex nonlinear transcendental equations; in this paper we propose a combination of one of the best existing optimized hardware structures with the recent firefly algorithm, which was used to optimize the THD, through finding the best switching angles and guaranteeing the minimization of harmonics within a user defined bandwidth. The obtained THD through the simulation of the thirteen-level symmetric inverter has been reduced down to 5% (FFT of 60 harmonics). In order to validate the simulation results, a thirteen-level symmetric inverter prototype has been made, and practically experimented and tested with different loads. Consequently, the measured THD with resistive load was 4.7% on a bandwidth of 3 kHz. The main advantage of the achieved work is the reduction of the THD.