bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Optimal Timing of Baseline Radiostereometric Analysis of Uncemented Press Fit Cups
Authors: Wolf O. , Milbrink J. , Larsson S. , Mattsson P. , Mallmin H. 
Published: January 2017

Background and Aims: The baseline radiostereometric analysis (RSA) is usually performed during the first postoperative week. We investigated the micromotion of two uncemented press fit acetabular cups during the first week after total hip arthroplasty. Material and Methods: All study patients had unilateral osteoarthritis of the hip and received an uncemented THA combination consisting of a CLS stem and either an Allofit or an Interop acetabular cup. The study group consisted of 24 patients who underwent RSA within 1 hour after skin closure, and at 1 and 7 days after surgery. Results: The upper limit of the 95% confidence interval for micromotion was less than or close to the precision of the method for all studied directions during the first week after surgery. Mean values indicate proximal and medial translation of the uncemented cup at one week. Conclusions: We found only minimal micromotion, barely above the precision limit, measured as medial and proximal translations of these uncemented cups. This indicates that the first postoperative RSA measurement following a primary THA with an uncemented press fit acetabular cup should be made as early as possible after the first postoperative day.
Losing It: Politics of the Other (Medium)
Authors: Bal Mieke 
Published: January 2017

Finnish cinematographer Eija-Liisa Ahtila makes video installations of a particularly griping intensity, staging a contact zone for encounters with otherness. They also deploy other media, such as literature, and other genres, such as documentary, along with other states of being, such as murder, maidenhood, and madness. This multiple otherness, I argue here, is crucial for the understanding of the way this artist uses a medium that is ostensibly visual to make environments that are political through encompassing engagements with otherness as other media. In the reception of her work, this heterogeneity is largely ignored in favour of interpretations of the installations anchored in a single medium – video installation – and a political individualism. This is most clear in the reception of The House, Ahtila’s best-known work. This is consistently interpreted as a representation of schizophrenia. That such negligence of a sophisticated heterogeneity has political consequences becomes obvious once we see that the ‘madness’ of the character in that piece is the symptom of her alterity, and is staged through a discrepancy between image and sound – the schizophrenia of the medium. In this essay I briefly revisit three of Ahtila’s best-known pieces in relation to an ‘other’ discourse: literature, psychoanalysis, and philosophy. In each, both the other media and the otherness of people take very different forms. In each case, though, the alterities of medium and subject matter coincide to reinforce the point that is basic to all of Ahtila’s work: the encounter with otherness on a non-exclusionary basis, as, also, an encounter with the otherness without ourselves. In the last section I also bring in two works by other artists, to make a case for a political potential inherent in the art form of video installation.
Modified Technique for Recovering Aortoiliac Homografts
Authors: Tamazashvili Tamaz , Yushkov Yuriy Y. , Roca Michael 
Published: January 2017

Background Infection of the prosthetic aortic graft bypass remains one of the most serious complications of aortoiliac bypass grafts. Use of an aortoiliac allograft as a replacement for an infected prosthetic graft is an effective treatment for this problem. However, the availability of aortoiliac grafts is affected by the high rate of procurement errors experienced during recovery. This overall error rate nationally averaged 32.5% in 2006, of which nearly a third (9.6%) were related to tears of the intima at or below the bifurcation of the abdominal aorta. Objective To analyze the potential of a new aortoiliac graft recovery method in reducing the error rate. Method A modified technique of aortoiliac graft recovery was used to minimize the possibility of intimal tears. The essence of this technique is to change the sequence of mobilization of the graft, starting from the zone of low resistance, which is at the iliac arteries, and continuing upward to the abdominal aorta, which has higher resistance because of the greater thickness of the aortic wall. An additional modification of the standard technique is to use a tourniquet to raise the aortic edges. Conclusion The aortoiliac graft has various resistances to tearing owing to the different wall thicknesses of the aorta and the iliac arteries. Mobilization of the abdominal aorta before dissection of the iliac arteries creates a high risk of tears at and around the bifurcation of the aorta and the iliac arteries.
Comparative Analysis of Clinical Efficacy and Cost between University of Wisconsin Solution and Histidine-Tryptophan-Ketoglutarate
Authors: Bellamy Chris A. , Nicely Bruce , Mattice Burton J. , Teaster Rob 
Published: January 2017

Objective To compare University of Wisconsin solution (Viaspan), the universal standard for organ preservation, with histidine-tryptophan-ketoglutarate solution. An analysis of each solution, in reference to clinical trials with specific organs, is presented and assessed to find the efficacy of each in a clinical environment. Also to view each solution from an economical standpoint, and in the end develop an overall understanding of the key similarities and differences between each solution in order to assess appropriate use of each in a clinical setting. Data Sources A literature search was conducted by using PubMed, MEDLINE, BIOSIS, Embase, and other online data bases to find the most recent studies of University of Wisconsin and histidine-tryptophan-ketoglutarate solutions. Search terms included University of Wisconsin solution, histidine-tryptophan-ketoglutarate, preservation solution, cost analysis, biliary complication, and other related subjects. Study Selection Previous research was selected from the literature search to provide basic information on the 2 solutions and also to provide clinical examples of each solution and the efficacy of each with specific organs. Data Synthesis Information and published articles on the 2 solutions were gathered for descriptive and comparative purposes. Conclusions The 2 solutions appear equally effective in organ preservation. Each solution has its own organ-specific qualities, and each has different complications. The studies reviewed here indicate that the differences are minor and thus suggest that the 2 solutions are equally acceptable for clinical use. Of the 2 solutions, histidine-tryptophan-ketoglutarate costs less than University of Wisconsin solution.
Prevalence and Correlates of Influenza Vaccination among Kidney Transplant Patients
Authors: Berben Lut , Denhaerynck Kris , Schaub Stefan , De Geest Sabina 
Published: January 2017

Context Immunosuppressive regimens increase kidney transplant patients' risk of contracting life-threatening influenza. However, little information exists about the prevalence and correlates of influenza vaccinations in this population. Objective To determine the prevalence and explore correlates of influenza vaccination in kidney transplant recipients. Design, Sample, and Setting This cross-sectional study used data from the Supporting Medication Adherence in Renal Transplantation study. The convenience sample consisted of 356 adult kidney transplant recipients (58.1% male; mean age, 52.9 [SD 13.53] years) recruited from 2 Swiss transplant outpatient clinics. Influenza vaccination status was assessed by self-report (yes/no). Main Outcome Measure Known correlates of vaccination in chronically ill patients (older age, cohabitation, higher education, higher socioeconomic status, financial stability, more comorbid diseases, nonsmoking status, and clinical site where care is received) were entered into a multiple logistic regression model. Results Of the 356 patients, only 83 (23.3%) reported having been vaccinated against influenza in the previous year. Positive vaccination status was significantly related to older age (odds ratio, 1.04; 95% confidence interval, 1.02–1.06). Conclusion Despite national and international guidelines recommending influenza vaccination in kidney transplant recipients, the prevalence of influenza vaccination in this sample was low. This study's results suggest that transplant centers need to implement policies to maximize influenza vaccination of their patients.
Attitude of Nursing Staff toward Organ Donation in a Spanish Hospital with a Solid-Organ Transplant Program
Authors: Zambudio Antonio Ríos , Martínez-Alarcón Laura , Parrilla Pascual , Ramírez Pablo 
Published: January 2017

Context Nursing personnel are fundamental in the organ donation and transplantation process, and their attitude toward donation has a decisive effect on patients, patients' families, and the general public. Objective To analyze the attitudes of nursing personnel toward donation in a transplant hospital and the factors that determine those attitudes. Materials and Methods A random sample of 305 nurses in different hospital services was taken and stratified by type of service. A validated psychosocial questionnaire was used to evaluate attitudes toward donation. The survey was completed anonymously and was self-administered. Student t test, χ2 test, and logistic regression analysis were used for statistical analysis. Results Most respondents (63%) favored organ donation. The following variables affected attitude: (1) having a favorable attitude toward donation of a family member's organs ( P < .001), (2) knowing the concept of brain death ( P < .001), (3) having discussed organ donation and transplantation within the family ( P = .001), (4) having a favorable attitude toward autopsy ( P = .006), (5) fearing mutilation of the body ( P < .001), (6) a partner's attitude toward organ donation and transplantation ( P < .001), and (7) the respondent's religion ( P = .009). Multivariate analysis yielded the following significant factors: (1) fear of mutilation of the body (odds ratio, 9.5), (2) partner's attitude toward organ donation and transplantation (odds ratio, 0.2), and (3) respondent's religion (odds ratio, 2.7). Conclusions Attitudes toward organ donation among nurses are similar to attitudes of the general public in Spain. Given the influence of nurses on the general public, promotional campaigns directed at nurses are a priority.
Preclinical Evaluation of 18F-ML-10 to Determine Timing of Apoptotic Response to Chemotherapy in Solid Tumors
Authors: Demirci Emre , Ahmed Rafay , Ocak Meltem , Latoche Joseph , Radelet April , DeBlasio Nicole , Mason N. Scott , Anderson Carolyn J. , Mountz James M. 
Published: January 2017

Purpose: We investigated 2-(5-fluoro-pentyl)-2-methyl-malonic acid (18F-ML-10) positron emission tomography (PET) imaging of apoptosis posttherapy to determine optimal timing for predicting chemotherapy response in a mouse head/neck xenograft cancer model. Procedures: BALB/c nude mice (4-8 weeks old) were implanted with UM-SCC-22B tumors. The treatment group received 2 doses of doxorubicin (10 mg/kg, days 0, 2). Small animal 18F-ML-10 PET/computed tomography was performed before and on days 1, 3, and 7 postchemotherapy. Using regions of interest around tumors, 18F-ML-10 uptake change was measured as %ID/g and uptake relative to liver. Terminal Uridine Nick-End Labeling (TUNEL) immunohistochemistry assay was performed using tumor samples of baseline and on days 1, 3, and 7 posttreatment. Results: Treated mice demonstrated increased 18F-ML-10 uptake compared to baseline and controls, and 10 of 13 mice showed tumor volume decreases. All control mice showed tumor volume increases. Tumor-to-liver (T/L) ratios from the control group mice did not show significant change from baseline ( P > .05); however, T/L ratios of the treatment group showed significant 18F-ML-10 uptake differences from baseline compared to days 3 and 7 posttreatment ( P < .05), but no significant difference at 1 day posttreatment. Conclusion: 2-(5-Fluoro-pentyl)-2-methyl-malonic acid PET imaging has the potential for early assessment of treatment-induced apoptosis. Timing and image analysis strategies may require optimization, depending on the type of tumor and cancer treatment.
Significance of Volume Embolization Ratio as a Predictor of Recanalization on Endovascular Treatment of Cerebral Aneurysms with Guglielmi Detachable Coils
Authors: Uchiyama N. , Kida S. , Nomura M. , Hasegawa M. , Yamashima T. , Yamashita J. , Matsui O. 
Published: January 2017

The purposes of this study are, firstly, to define the relationship between volume embolization ratio (VER) and degree of angiographical occlusion in endovascular treatment with Guglielmi detachable coils, and secondly, to examine influences of neck and dome sizes of aneurysms on the VER and the angiographical treatment result, and thirdly, to determine the relationship between the VER and the recanalization of coiled aneurysms. Fifty-two aneurysms in 46 patients were examined. VER ranged 8.1–31.9% (mean 18.5%). The mean VERs of each categories based on angiographical treatment results were 23.1% in complete occlusion, 16.1% in neck remnant and 12.2% in incomplete occlusion, respectively. The VER correlated significantly with both neck and dome size, while the angiographical treatment result was only affected by neck size. Five aneurysms showed aneurysmal recanalization among followed-up 41 aneurysms. All recanalized aneurysms were large, and their VERs were in range of 10.4–17.6%. Measurement of VER is useful to estimate the degree of occlusion objectively and to predict the aneurysmal recanalization. A small aneurysms with a small neck is relatively easy to achieve high VER and angiographical complete occlusion, with the consequence of less recanalization. On the other hand, a large aneurysm is liable to recanalize due to low VER, even if there was little filling of contrast medium in the aneurysmal cavity.
Endovascular Treatment with GDC for Severe Acute SAH: Comparison with Early Direct Surgery
Authors: Kobayashi S. , Satoh A. , Koguchi Y. , Yamauchi T. , Itoh S. , Ooishi H. , Nakamura H. , Yagishita T. , Watanabe Y. 
Published: January 2017

The purpose of this study was to evaluate the effect of endovascular treatment with Guglielmi detachable coils (GDC) on the outcome of severe subarachnoid hemorrhage (SAH) caused by acute rupture of a cerebral aneurysm and on the incidence of symptomatic vasospasm. Thirty-five patients with aneurysmal SAH were treated in the acute stage using GDC. Fifteen out of 17 patients in Hunt & Kosnik grades I, II, and III showed good recovery (GR) at discharge, while one was moderately disabled (MD) and one was severely disabled (SD). Among 16 patients in poor neurological condition (GCS was ⩽ 9 on admission), the outcome was GR in 5 cases (31%), MD in 2 (13%), and SD in 9 (56%). These results were better than those for surgically treated patients with the same neurological status. The difference in outcome between endovascular treatment and surgery may have been related to the difference in the insult to the brain caused by each modality. The incidence of symptomatic vasospasm was lower in the GDC group (5.7%) than in the surgical group (12%). In the patients treated with GDC and intrathecal administration of urokinase, subarachnoid clots were cleared more rapidly than in those treated surgically with continuous cisternal irrigation. The accelerated clearance of subarachnoid clots in the GDC group might have helped to prevent delayed vasospasm. The long-term efficacy of GDC embolization in preventing subsequent bleeding has not yet been determined. However, this method seems to be less traumatic for the brain and may be suitable for treatment of patients with severe SAH.
A New Stent Graft
Authors: Nishi S. , Nakayama Y. , Ueda H. , Ishikawa M. , Matsuda T. 
Published: January 2017

The use of stents improves the result after balloon coronary angioplasty. Restenosis due to neointimal hyperplasia and proliferation of smooth muscle cells are, however, a concern. In the present report, we studied the prevention of restenosis to allow endothelial cell migration and growth to proceed through micropores using our developed stent graft with micropored segmented polyurethane (SPU) thin film in a normal beagle model. Our developed stent graft was made from Palmaz stent and micropored SPU thin film. The SPU film was arranged into four different micropore densities around the circumference: no micropores, arrangement 4; micropores of 30μm in diameter with an orderly distance of 250μm; (arrangement 1), 500μm; (arrangement 2) and 125μm (arrangement 3) between the neighboring two pores. Micropores were made using the Excimer laser ablation technique. The Palmaz stent was wrapped with micropored film, sutured, and glued with DMF (dimethyl formamide) under aid of a microscope. These stents were placed in the common carotid arteries of beagles (n = 5). They were sacrificed at 1 month, and a histological study and scanning electron microscopy study were performed for evaluation of endoluminal endothelialization. In 10 arteries applied with stent grafts, there was no severe stenosis although it did occur to some extent. All stented arteries were patent. Endothelial cell migration and growth through micropores were observed histologically on micropored SPU thin film in this model, which did not affect the intraluminal diameter. In most non-porous regions, significant thrombi were found between the SPU film and the neointimal layer. On the other hand, in the porous region, little thrombosis was observed except in the lowest density region. In 125μm of distance between two neighboring pores, the neointimal layer was the thinnest, which was suitable for wide intraluminal space after placement of a stent graft. Endothelial cell migration and growth through micropores were confirmed in the animal model using our developed micropored stent graft. The proceeding of their migration was controlled by micropore density under a constant micropore diameter. The stent graft with micropored SPU thin film is promising for the prevention of restenosis due to neointimal hyperplasia.
Reversibility of Ischemia Evaluated by Ischemic Duration and Residual Cerebral Blood Flow
Authors: Nakano S. , Iseda T. , Goya T. , Wakisaka S. 
Published: January 2017

We first investigated the time course of CBF thresholds of ischemic cortices by a retrospective review of 19 patients with MCA occlusion who had clearly defined ischemic duration from onset to angiographic complete recanalization. Secondly, CBF thresholds of ischemic cortices salvageable with intravenous low dose native t-PA infusion therapy (7.2 mg of tisokinase) were examined by a retrospective review of 20 patients with distal embolic occlusions of MCA divisions or branches. All patients underwent pretreatment CBF measurement by SPECT using 99mTc-ECD. Pretreatment SPECT and 3 months post-treatment CT images were compared using computerized coregistration. The degree of hypoperfusion was analyzed by an asymmetry index (AI), which was a count-density ratio for the ischemic lesion to the contralateral corresponding area. Ischemic cortices on SPECT were divided into reversible and irreversible lesions. Judging from the regression lines with 95% confidence interval between the ischemic duration and AI, the infarcted CBF thresholds at 3 and 6 hours after onset may be about 30 and 50% of contralateral presumed normal CBF, respectively. On the other hand, to save the ischemic tissue with our intravenous t-PA infusion therapy, residual CBF might be needed at least 45% of contralateral presumed normal CBF. It is likely that CBF threshold of ischemia surely salvageable with our intravenous t-PA infusion therapy may be approximately 50–55% of contralateral presumed normal CBF.
Local Fibrinolysis for Middle Cerebral Artery Embolism Criteria for the Indication by Evaluation of Residual Cerebral Blood Flow and the Results
Authors: Hyogo T. , Kataoka T. , Hayase K. , Nakagawara J. , Takeda R. , Nakamura H. 
Published: January 2017

We summarize our clinical experience of the local fibrinolysis for the middle cerebral artery (MCA) embolism. We added residual CBF factors of the ischemic territories to the usual criteria for the indication of fibrinolysis by Xe-SPECT CBF measurement. Forty-nine cases of local fibrinolysis for MCA embolism were reviewed and the results were compared with the conservative medical treatment cases. Angiographical improvements were achieved in 38 cases (76%, full reopening 17/49, partial reopening 21/49) and favorable outcomes (good recovery at GOS) were obtained in 32 cases (65%) at three months follow-up outcome. In comparison with the conservative medical treatment, fibrinolysis was superior at good recovery rate, severe disability rate and the resulted large infarction rate with statistical significance. We concluded that the local fibrinolysis with evaluation of the residual CBF of the ischemic territories achieved good results and outcomes and superior to the conservative medical treatment at some points. To keep the therapeutic time window, it is necessary to include the CBF factor to the criteria for the indication of this treatment.
Critical Pathway and Hospital-Hospital Cooperation in Acute Stroke Reduction of the Length of Hospital Stay
Authors: Hashimoto Y. , Terasaki T. , Yonehara T. , Tokunaga M. , Hirano T. , Uchino M. 
Published: January 2017

Stroke patients tend to stay longer in one hospital compared to patients with other neurological disease. After the introduction of 3 types of critical pathway dedicated for various severity of acute ischemic stroke in 1995, the average length of in-hospital days declined from 30.0 days (1993) to 15.3 days (1998), ie 49% reduction. This reduction was achieved by the use of critical pathway and the hospital-hospital cooperation.
Technical Note on VDS
Authors: Henkes H. , Drepper P. , Speder J. , Felber S. , Monstadt H. , Kühne D. 
Published: January 2017

A new system was deviced that allows the electrolytical detachment of platinum microcoils at variable lengths for the endovascular treatment of intracranial aneurysms. The detachment element consists of two short platinum coil segments, which are connected by a threat of stainless steel. The steel threat is interrupted by electrolysis, using a continuous current with 1–2 mA at a voltage of 4–8 Volt. The average detachment time in heparinized blood is about 30–40 sec. The detachment elements can be used to connect either an insertion wire with a platinum coil or to connect several segments of platinum coils with variable helices and lengths. If several detachment elements are integrated in a coil, electrolysis interrupts only the element, which is next beyond the distal tip of the catheter. The electrolytical process does not affect the detachment elements proximal and distal to the element adjacent to the tip of the catheter. Single or several coil segments can be pulled back into the microcatheter if necessary. The system is expected to allow a faster and more complete endovascular coil occlusion of intracranial aneurysms. The principles described in this paper are claimed by the German pending patent DE 100 10840 A1.