bluuebunny/crossref_metadata_2025_split huggingface dataset:
Team problem solving and motivation under disorganization – an agent-based modeling approach
Authors: Herath Dinuka , Costello Joyce , Homberg Fabian 
Published: April 2017

PurposeThis paper aims at simulating on how “disorganization” affects team problem solving. The prime objective is to determine how team problem solving varies between an organized and disorganized environment also considering motivational aspects.Design/methodology/approachUsing agent-based modeling, the authors use a real-world data set from 226 volunteers at five different types of non-profit organizations in Southwest England to define some attributes of the agents. The authors introduce the concepts of natural, structural and functional disorganization while operationalizing natural and functional disorganization.FindingsThe simulations show that “disorganization” is more conducive for problem solving efficiency than “organization” given enough flexibility (range) to search and acquire resources. The findings further demonstrate that teams with resources above their hierarchical level (access to better quality resources) tend to perform better than teams that have only limited access to resources.Originality/valueThe nuanced categories of “(dis-)organization” allow us to compare between various structural limitations, thus generating insights for improving the way managers structure teams for better problem solving.
Escape from the factory of the robot monsters: agents of change
Authors: Richards Dale 
Published: April 2017

PurposeThe increasing use of robotics within modern factories and workplaces not only sees us becoming more dependent on this technology but it also introduces innovative ways by which humans interact with complex systems. As agent-based systems become more integrated into work environments, the traditional human team becomes more integrated with agent-based automation and, in some cases, autonomous behaviours. This paper discusses these interactions in terms of team composition and how a human-agent collective can share goals via the delegation of authority between human and agent team members.Design/methodology/approachThis paper highlights the increasing integration of robotics in everyday life and examines the nature of how new novel teams may be constructed with the use of intelligent systems and autonomous agents.FindingsAreas of human factors and human-computer interaction are used to discuss the benefits and limitations of human-agent teams.Research limitations/implicationsThere is little research in (human–robot) (H–R) teamwork, especially from a human factors perspective.Practical implicationsAdvancing the author’s understanding of the H–R team (and associated intelligent agent systems) will assist in the integration of such systems in everyday practices.Social implicationsH–R teams hold a great deal of social and organisational issues that need further exploring. Only through understanding this context can advanced systems be fully realised.Originality/valueThis paper is multidisciplinary, drawing on areas of psychology, computer science, robotics and human–computer Interaction. Specific attention is given to an emerging field of autonomous software agents that are growing in use. This paper discusses the uniqueness of the human-agent teaming that results when human and agent members share a common goal within a team.
Agent-based models of bounded rationality
Authors: Secchi Davide 
Published: April 2017

Purpose
The purpose of this editorial is to introduce the Special Issue “Agent-Based Models of Bounded Rationality” and to provide an overview of its rationale and main objectives.

Design/methodology/approach
After outlining the overall framework to justify the choice of agent-based modeling in relation to bounded rationality, an overview of the six papers published in the Special Issue is presented.

Findings
The paper argues that simulation of complex adaptive social systems is a way to set the ground for updating the concept of bounded rationality and prepare for it to still play a significant role in the years to come.

Originality/value
After its introduction, bounded rationality remained mostly used but seldom discussed in both its assumptions and its meaning. The originality of this introduction is to unveil some of the points that keep rationality still at the core of organization and team research.
Evaluation of physicochemical, microbiological, sensory properties and aroma profiles of goat cheeses provided from Canakkale
Authors: Ozmen Togay Sine , Guneser Onur , Karagul Yuceer Yonca 
Published: April 2017

The purpose of this study was to determine physicochemical and sensory properties, aroma‐active compounds and number of lactic acid bacteria in goat cheeses. High variation was observed among the cheeses in terms of fat %(w/w) and salt %(w/w) contents and titratable acidities %(w/w). Average counts of lactococci lactobacilli and enterococci were 6.90, 6.43 and 5.26 log cfu (colony‐forming unit)/g, respectively. The following compounds had high aroma intensity in the cheeses: acetic acid, butanoic acid, hexanoic acid, p‐cresol and phenyl acetic acid. Cooked, whey, creamy, animal‐like, waxy, salty and sour were the characteristic sensory descriptors.
Traditional milk processing and value‐added dairy products in selected Arab countries
Authors: Wilson Richard Trevor 
Published: April 2017

The 22 countries of the Arab League occupy a combined area of 13.13 million square kilometres extending from the Atlantic coast of Africa in the west to Mesopotamia in the east. The total human population is of the order of 356.8 million people. Livestock (camel, sheep, goat and cow) have been kept by the Arabs for thousands of years and continue to be important in household and national economies. This article identifies and describes traditional milk processing activities and their derived products in a selection of countries of the area.
Incidence of secondary glaucoma after treatment of uveal melanoma with robotic radiosurgery versus brachytherapy
Authors: Siedlecki Jakob , Reiterer Veronika , Leicht Simon , Foerster Paul , Kortüm Karsten , Schaller Ulrich , Priglinger Siegfried , Fuerweger Christoph , Muacevic Alexander , Eibl‐Lindner Kirsten 
Published: April 2017

ABSTRACTPurposeDifferent modalities of radiation therapy nowadays allow for effective treatment of uveal melanoma combined with the advantage of eye preservation. However, this advantage can secondarily be impaired by radiation‐related side effects. After local recurrence, secondary glaucoma (SG) has been described as second most frequent complication leading to need of enucleation. This study compares the incidence of SG after conventional Ruthenium (Ru)‐106 brachytherapy (BT) versus CyberKnife robotic radiosurgery (RRS) which has been gaining importance lately as an efficient treatment option offering improved patient comfort.MethodsMedical records of all patients diagnosed with uveal melanoma in the Eye Clinic of the Ludwig‐Maximilians‐University Munich between 2007 and 2013 were reviewed. A total of 268 eyes of 268 patients treated with Ru‐106 BT or CyberKnife‐RRS as monotherapy were entered in this retrospective cohort study. Incidence of SG was correlated with treatment modality and baseline tumour characteristics.ResultsFifty‐three patients (19.8%) developed SG. At 5 years, SG was significantly more frequent after RRS (46.7%) than BT (11.1%); however, tumour thickness (maximum apical height) as a marker of tumour progress was more pronounced in the RRS group. Subgroup analysis of 178 patients for tumours amenable to both BT and RRS (thickness ≤6 mm) revealed comparable results at 3 years (RRS: 13.8 versus BT: 11.2%), but a trend towards increased incidence after RRS beyond year three. However, this difference was not significant at 5 years (28.2% versus 11.2%, p = 0.138). Tumour thickness was significantly associated with incidence of SG.ConclusionIn tumours ≤6 mm thickness, RRS and BT seem to offer a comparable safety profile in terms of SG. Beyond year three, SG was tendentially, but not significantly more frequent after RRS. Increasing tumour thickness is associated with risk of SG.
Laparoscopy‐assisted full‐thickness resection of the duodenum for patients with gastrointestinal stromal tumor with ulceration
Authors: Abe Nobutsugu , Hashimoto Yoshikazu , Takeuchi Hirohisa , Ohki Atsuko , Nagao Gen , Suzuki Yutaka , Masaki Tadahiko , Mori Toshiyuki , Sugiyama Masanori 
Published: April 2017

AbstractIntroductionGastrointestinal stromal tumor (GIST) with ulceration may potentially disseminate into the peritoneal cavity after laparoscopic local wedge resection (full‐thickness resection) when the intestinal wall is opened under the aeroperitoneum. To prevent this intraoperative tumor seeding, we developed laparoscopy‐assisted full‐thickness resection (LAFTR) of the duodenum for GIST with ulceration. Here, we present the preliminary results of LAFTR.MethodsThree patients with duodenal GIST with ulceration underwent LAFTR. LAFTR consists of four major procedures: (i) a laparoscopic Kocher maneuver (mobilization of the pancreatoduodenum); (ii) the creation of a small upper median laparotomy; (iii) the extracorporeal completion of the full‐thickness resection under direct vision; and (iv) extracorporeal hand‐sewn closure of the duodenal defect.ResultsLAFTR was successfully performed without any intraoperative adverse events. The mean operating time and estimated blood loss were 182 min and 34 mL, respectively. Postoperative contrast roentgenography showed neither duodenal deformity nor disturbance of gastroduodenal emptying in any of the patients. None of the patients developed peritoneal recurrence.ConclusionsLAFTR can eliminate the possibility of peritoneal or port‐site seeding of tumor cells because the duodenotomy and tumor excision are performed extracoporeally. Meticulously hand‐sewn closures of the duodenal defect can minimize the possibilities of anastomotic insufficiency and deformity. LAFTR is a feasible, safe, and minimally invasive treatment for patients with GIST with ulceration in the first and second portions of the duodenum.
CD49d associates with nodal presentation and subsequent development of lymphadenopathy in patients with chronic lymphocytic leukaemia
Authors: Strati Paolo , Parikh Sameer A. , Chaffee Kari G , Achenbach Sara J. , Slager Susan L. , Call Timothy G. , Ding Wei , Jelinek Diane F. , Hanson Curtis A. , Kay Neil E. , Shanafelt Tait D. 
Published: April 2017

SummaryCD49d is a surface integrin that is expressed on chronic lymphocytic leukaemia (CLL) cells, and strongly correlates with more aggressive disease. Given its association with cell‐cell adhesion and leucocyte trafficking, we hypothesized that patients with high CD49d expression would experience a clinical course dominated by lymphadenopathy. CD49d expression was measured by flow cytometry and considered positive if expressed by ≥30% of CLL cells. The study included 797 newly diagnosed CLL/small lymphocytic leukaemia patients; 279 (35%) were CD49d positive. CD49d‐positive patients were more likely to present with lymphadenopathy (P < 0·001); a finding that persisted after adjusting for fluorescence in situ hybridisation (FISH) and IGHV mutation status [odds ratio (OR) 2·51; 95% confidence interval (CI) 1·64–3·83; P < 0·001]. Among CLL Rai 0 patients, CD49d positivity was associated with shorter time to development of lymphadenopathy (3·2 years vs not reached, P < 0·01). This association was maintained after adjusting for either FISH [hazard ratio (HR) 2·18; 95% CI 1·25–3·81; P = 0·006) or IGHV status (HR 2·02; 95% CI 1·11–3·69; P = 0·02) individually, but was attenuated when adjusting by both (HR 1·72; 95% CI 0·88–3·38; P = 0·11).These data demonstrate that CD49d‐positive CLL patients experience a disease course dominated by lymphadenopathy. These findings could have implications for therapy selection and disease monitoring.
Pouch excision: indications and outcomes
Authors: Lightner A. L. , Dattani S. , Dozois E. J. , Moncrief S. B. , Pemberton J. H. , Mathis K. L. 
Published: April 2017

AbstractAimRestorative proctocolectomy with ileal‐pouch anal anastomosis is the procedure of choice for ulcerative colitis. Unfortunately, up to 10% of pouches will fail, requiring either reconstruction or excision. While several series have reported on the aetiology of pouch failure, no study to date has focused on the postoperative complications associated with pouch excision.MethodsPatients who had excision of ileoanal reservoir with ileostomy (CPT code 45136) were included. Data abstracted included preoperative, operative and postoperative variables. A Kaplan–Meier curve of pouch survival was performed.ResultsIn all, 147 patients met the inclusion criteria for the study. The median age of patients was 47 years (73 women), and 132 had a diagnosis of ulcerative colitis at the time of colectomy. The most common indications for pouch excision were sepsis (n = 46; 31%) and Crohn's disease (n = 37; 25%). 84 (57%) patients experienced short‐term (< 30 days) postoperative complications, the most common of which was a surgical site infection (n = 32; 21%); 55 (37%) patients had long‐term complications (> 30 days) postoperatively, the most common of which was a return to the operating room (n = 19; 13%) largely for perineal wounds. Thirty‐day mortality was zero. 4.8%, 47.6%, 65.3% and 84.4% of patients had undergone pouch excision by 1, 5, 10 and 20 years from the time of pouch construction, respectively.ConclusionsPouch excision has a high rate of both short‐ and long‐term postoperative complications. Patients should be appropriately counselled to set expectations accordingly. In view of these findings we suggest that this operation should ideally be performed at a high volume centre with the availability of a multidisciplinary surgical team.
Locking out predators by silk, a new counterattack behaviour in a social spider mite
Authors: SAITO YUTAKA , ZHANG YANXUAN 
Published: April 2017

1. A type of arms race that includes predation, counterattacks and cross‐counterattacks occurs between the phytophagous mite Stigmaeopsis nanjingensis (Ma et Yuan), which lives in self‐woven nests and exhibits cooperative sociality, and its specialised phytoseiid mite predator, Typhlodromus bambusae Ehara.2. First, the efficiency of the S. nanjingensis (prey) counterattacking T. bambusae (predator) was observed. The prey females frequently locked the immature predators out of their nests using silk web, and the predators subsequently died of starvation. Furthermore, the prey males often killed immature T. bambusae mites after they invaded the nests.3. This reversal of roles in the predator–prey system was then re‐reversed (returned to a normal state) by the behaviour of T. bambusae females. Immature predators could maintain their predacious natures due to the presence of attending adult females, which are able to cope with the prey counterattack behaviours.
Introduction—Pediatric epilepsy surgery techniques
Authors: Rydenhag Bertil , Cukiert Arthur 
Published: April 2017

SummaryThis supplement includes the proceedings from the Pediatric Epilepsy Surgery Techniques Meeting held in Gothenburg (July 4–5, 2014), which focused on presentations and discussions regarding specific surgical technical issues in pediatric epilepsy surgery. Pediatric epilepsy neurosurgeons from all over the world were present and active in very fruitful and live presentations and discussions. These articles represent a synopsis of the areas and subjects dealt with there.
Technical descriptions of four hemispherectomy approaches: From the Pediatric Epilepsy Surgery Meeting at Gothenburg 2014
Authors: Baumgartner James E. , Blount Jeffrey P. , Blauwblomme Thomas , Chandra P. Sarat 
Published: April 2017

SummaryHemispherectomy is a complex multistep procedure with a steep learning curve. Several surgical approaches have been developed, but each requires considerable practice to master. Four experienced pediatric neurosurgeons, who participated in the 2014 Gothenburg Pediatric Epilepsy Surgery Meeting, provided succinct technical summaries of four hemispherectomy approaches: modified functional hemispherectomy, peri‐insular hemispherotomy, parasagittal hemispherotomy, and endoscopic‐assisted hemispherotomy. No clinical or outcome data are included. Our intention is to reduce the slope and length of the learning curve for surgeons and to improve the understanding of the technical details of hemispherectomy surgery by nonsurgeonmembers of epilepsy teams.
Corpus callosotomy—Open and endoscopic surgical techniques
Authors: Smyth Matthew D. , Vellimana Ananth K. , Asano Eishi , Sood Sandeep 
Published: April 2017

SummaryCorpus callosotomy is a palliative surgical procedure for patients with refractory epilepsy. It can be performed through an open approach via a standard craniotomy and the aid of an operating microscope, or alternatively via a mini‐craniotomy with endoscope assistance. The extent of callosal disconnection performed varies according to indications and surgeon preference. In this article, we describe both open and endoscopic surgical techniques for anterior and complete corpus callosotomy.
Deep brain stimulation targeting in refractory epilepsy
Authors: Cukiert Arthur , Lehtimäki Kai 
Published: April 2017

SummaryDeep brain stimulation has been used in increasing frequency to treat refractory epilepsy. Different targets have been tried, and different epileptic syndromes have been addressed in different ways. We describe the current targeting techniques for the structures presently most often implanted, namely the anterior nucleus of the thalamus, the centromedian nucleus of the thalamus, and the hippocampus.
Placental passage of antiepileptic drugs at delivery and neonatal outcomes
Authors: Bank Anna M. , Stowe Zachary N. , Newport D. Jeffrey , Ritchie James C. , Pennell Page B. 
Published: April 2017

SummaryChildren of women treated with antiepileptic drugs (AEDs) are at increased risk of adverse outcomes detectable in the neonatal period, which may be associated with the amount of AEDs in the fetal circulation. Placental passage of AEDs can be measured by calculating the ratio of umbilical cord to maternal AED concentrations collected at delivery. The aims of this study were to determine the umbilical cord concentrations and umbilical‐to‐maternal ratios for AEDs, and whether higher cord concentrations are associated with increased risk of neonatal complications. AED cord and maternal blood concentrations from 70 mother–newborn dyads and neonatal complications were recorded. Logistic regressions were performed to determine the association between AED concentrations and complications. Mean umbilical‐to‐maternal ratios for total concentrations ranged from 0.79 for carbamazepine to 1.20 for valproic acid, and mean umbilical‐to‐maternal ratios for free concentrations ranged from 0.86 for valproic acid to 1.42 for carbamazepine, indicating complete placental passage. Neither umbilical cord concentrations nor umbilical‐to‐maternal ratios were associated with adverse neonatal outcomes. Additional investigations are warranted to delineate the relationship between quantified fetal AED exposure and neonatal complications.
Sphenopalatine Ganglion (SPG): Stimulation Mechanism, Safety, and Efficacy
Authors: Tepper Stewart J. , Caparso Anthony 
Published: April 2017

ObjectiveTo describe the history of and available data on sphenopalatine ganglion (SPG) neuromodulation in the treatment of headache up to the present.BackgroundThe SPG has been a therapeutic target to treat primary headache disorders for over 100 years. Multiple destructive lesions have also been tried with variable rate and duration of success. Neurostimulation of the SPG for cluster headache was first described in 2007.MethodsThis is not a systematic review. The authors review the anatomy and pathophysiology of the SPG and cluster headache and the important clinical trials, relating a history of how SPG neuromodulation reached the current state of approval in the European Union (EU) and pivotal registration study for cluster headache in the US.ResultsThe EU approved SPG stimulation for cluster headache with a CE Mark in February of 2012. Since then, several EU countries have elected to reimburse implantation for cluster headache, and over 300 patients have been implanted worldwide.ConclusionsSuccess rates for implanted SPG neuromodulation in the experimental phase of the European randomized controlled trial, in the open label extension trial, and in the registry of patients implanted outside of the trial remain at about two‐thirds of patients implanted being responders, defined as being able to terminate at least 50% of attacks or having at least a 50% decrease in attack frequency or both. A US pivotal registration study is underway to confirm these results and obtain FDA approval for this treatment for cluster headache patients. Further studies in migraine are also underway.
Sella turcica bridging and dental anomalies: is there an association?
Authors: Scribante Andrea , Sfondrini Maria Francesca , Cassani Marco , Fraticelli Danilo , Beccari Sergio , Gandini Paola 
Published: April 2017

BackgroundSella turcica bridging (STB), or calcification of the interclinoid ligament of sella turcica, has been reported to be associated with some dental anomalies (palatal canine impaction and transposition).Hypothesis or AimThe aim of the study was to find any association between canine impaction, hyperdontia or hypodontia and sellar dimensions or bridging.DesignLateral cephalometric radiographs from 78 patients with impacted canines, 68 with dental agenesis and 17 with hyperdontia were collected. Linear dimensions of sella turcica were calculated and compared to those of a control group (47 individuals). A standardize scoring scale was used to quantify the extent of STB from each radiographs.ResultsThe frequency of partial and complete calcifications of sella in patients with dental anomalies is increased when compared to controls. STB can influence the interclinoid distance but does not affect other linear dimensions of sella. No statistically significant difference has been found in sellar dimensions and STB expression when evaluating radiographs at different ages.ConclusionsSTB is frequently found in patients with dental abnormalities.