bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unpacking interplays between competitiveness, cooperativeness, and social comparison orientation: A network psychometric approach and replication
Authors: Meng Guangteng , Wang Lingxiao , Zhong Bowei , Wang Shujing , Li Qi , Liu Xun 
Published: September 2024

AbstractEmerging evidence highlights the role of social comparison in competition and cooperation, yet the dynamics among competitiveness, cooperativeness, and social comparison orientation (SCO) remain underexplored. In the present study, we sought to unravel these complex interplays employing graphical Gaussian models (GGMs) and characterize the network structures utilizing cross‐sectional data derived from 1073 Chinese participants. A pre‐registered independent sample (n = 1348) served to examine the replicability and robustness of our initial findings. Moreover, we explored the Bayesian networks (i.e., directed acyclic graphs) to delve into their probabilistic directed dependencies. Our analysis identified an interpersonal co‐opetition network where SCO bridges competitiveness and cooperativeness, emphasizing the key influence of the desire to surpass others. We also found a significant gender effect on the levels of these orientations but not on the network patterns. Additionally, the replication sample offered validation for the resultant network structure and its key nodes. In sum, these findings provide a new insight into the symbiotic relationship between competitiveness and cooperativeness within the framework of social comparison, offering significant theoretical and practical implications.
Differences in mutations across tumour sizes in clear‐cell renal cell carcinoma
Authors: Monda Steven M. , Carney Benjamin W. , May Allison M. , Gulati Shuchi , Salami Simpa S. , Chandrasekar Thenappan , Keller Evan T. , Huebner Nicolai A. , Palapattu Ganesh S. , Dall'Era Marc A. 
Published: September 2024

ObjectiveTo assess the distribution of key mutations across tumour sizes in clear‐cell renal cell carcinoma (ccRCC), and secondarily to examine the prognostic impact of aggressive mutations in smaller ccRCCs.Patient and MethodsThe distribution of mutations (VHL, PBRM1, SETD2, BAP1 and CDKN2A loss) across tumour sizes was assessed in 1039 ccRCCs treated with nephrectomy in cohorts obtained from the Tracking Cancer Evolution (TRACERx), The Cancer Genome Atlas (TCGA) and the Cancer Genomics of the Kidney (CAGEKID) projects. Logistic regression was used to model the presence of each mutation against size. In our secondary analysis, we assessed a subset of ccRCCs ≤7 cm for associations of key aggressive mutations (SETD2, BAP1, and CDKN2A loss) with metastasis, invasive disease and overall survival, while controlling for size. A subset of localised tumours ≤7 cm was also used to assess associations with recurrence after nephrectomy.ResultsOn logistic regression, each 1‐cm increase in tumour size was associated with aggressive mutations, SETD2, BAP1, and CDKN2A loss, at odds ratios (ORs) of 1.09, 1.10 and 1.19 (P < 0.001), whereas no significant association was observed between tumour size and PBRM1 (OR 1.02; P = 0.23). VHL was mildly negatively associated with a 1‐cm increase in size (OR 0.95; P = 0.01). Among tumours ≤7 cm, SETD2 and CDKN2A loss were associated with metastatic disease at ORs of 3.86 and 3.84 (P < 0.05) while controlling for tumour size. CDKN2A loss was associated with worse overall survival, with a hazard ratio (HR) of 2.19 (P = 0.03). Among localised tumours ≤7 cm, SETD2 was associated with worse recurrence‐free survival (HR 2.00; P = 0.03).ConclusionLarge and small ccRCCs are genomically different. Aggressive mutations, namely, SETD2, BAP1, and CDKN2A loss, are rarely observed in small ccRCCs and are observed more frequently in larger tumours. However, when present in tumours ≤7 cm, SETD2 mutations and CDKN2A loss were still independently associated with invasive disease, metastasis, worse survival, and recurrence after resection, after controlling for size.
Atopic dermatitis and hand eczema in Danish adults: A nationwide population‐based study
Authors: Vinge Anna Schultz , Skov Lone , Johansen Jeanne Duus , Quaade Anna Sophie 
Published: September 2024

AbstractBackgroundAtopic dermatitis (AD) and hand eczema often co‐occur, particularly among adults.ObjectivesTo examine the interplay between AD and hand eczema in the general population, by characterising prevalence, disease severity, contact sensitization, and comorbidities in individuals with one or both conditions.Materials and MethodsIn this cross‐sectional study, 100 000 randomly selected adults in the Danish general population received a questionnaire via a secure, digital mailbox linked to their civil registration number. Participants answered questions regarding eczema, disease severity, patch testing, and comorbidities.ResultsA total of 40 007 individuals responded to the question on a lifetime prevalence of AD, and the prevalence among adult Danes was 9.0%. Nearly one third of individuals with AD reported moderate to severe disease. AD was associated with contact sensitization and increased hand eczema prevalence. Individuals with both AD and hand eczema reported worse disease severity. Furthermore, having both conditions was associated with an increased risk of psychiatric comorbidities.ConclusionsThis study provided updated information about unselected adults with AD in Denmark. Individuals with both AD and hand eczema represent a vulnerable subgroup that physicians should be attentive to.
Impact of continuous glucose monitoring on hospitalizations and glucose control in people with type 2 diabetes: real‐world analysis
Authors: Garg Satish K. , Hirsch Irl B. , Repetto Enrico , Snell‐Bergeon Janet , Ulmer Brian , Perkins Christopher , Bergenstal Richard M. 
Published: September 2024

AbstractAimThe real‐world benefits of continuous glucose monitoring (CGM) in the broad type 2 diabetes (T2D) population are not well studied. Our study evaluated the impact of CGM use on health care resource utilization over 12 months in adults with T2D.Materials and MethodsThis retrospective cohort analysis used Optum's de‐identified Market Clarity data of >79 million people to evaluate CGM use in people with T2D who were treated with non‐insulin (NIT), basal insulin (BIT) and prandial insulin therapy (PIT). The primary outcomes were changes in all‐cause hospitalizations, acute diabetes‐related hospitalizations and acute diabetes‐related emergency room visits during the 6‐ and 12‐month post‐index period following transition from blood glucose monitoring to CGM. A pre‐specified subgroup analysis assessed glucose control and medication changes among people with T2D over 1 year.ResultsThe analysis included 74 679 adults with T2D (NIT; n = 25 269), (BIT; n = 16 264) and (PIT; n = 33 146). Significant reductions in all‐cause hospitalizations, acute diabetes‐related hospitalizations and acute diabetes‐related emergency room visits were observed in the 6‐month post‐index period that were sustained during the 6–12 month post‐index period (NIT, −10.1%, −31.0%, −30.7%; BIT, −13.9%, −47.6%, −28.2%; and PIT, −22.6%, −52.7%, −36.6%, respectively). A subgroup analysis of 6030 people showed mean glycated haemoglobin reductions at approximately 3 months, which were also sustained throughout the post‐index period: NIT, −1.1 (0.05)%; BIT, −1.1 (0.06)%; and PIT, −0.9 (0.04)%, p < 0.0001.ConclusionsCGM use in real‐life across different therapeutic regimens in adults with T2D was associated with reductions in health care resource utilization with improved glucose control over 1 year.
Prevalence of complications and co‐morbidities in males and females with obesity: Real‐world insights from claims data analysis
Authors: Bae Jay P. , Nelson David R. , Boye Kristina S. , Mather Kieren J. 
Published: September 2024

AbstractAimTo comprehensively examine the range of co‐morbidities among males and females with a diagnosis of obesity.Materials and MethodsThis cross‐sectional retrospective study used US commercial and Medicare claims data from Merative MarketScan Research Databases to identify adults (age ≥ 18 years) with a diagnosis of obesity with continuous insurance coverage from 2018 to 2020. Co‐morbidities were tabulated based on coded diagnoses, and prevalences were calculated in males and females across age groups. Age‐adjusted odds ratios (ORs) determined differences in co‐morbidities between the sexes.ResultsOf an eligible sample of 6.9 million, we identified 2 028 273 individuals with at least one obesity‐related International Classification of Diseases, 10th Revision, Clinical Modification code. The proportions of males and females with obesity were 43.0% versus 57.0%. The most prevalent co‐morbidities among males and females were hypertension (62.8% vs. 52.2%), dyslipidaemia (63.3% vs. 50.3%) and depression and/or anxiety (D/A; 29.7% vs. 48.5%). The prevalence of D/A was high in the younger age group, but steadily decreased with age in both sexes; however, hypertension and dyslipidaemia continued to increase with age. The presence of diagnosis of hypertension and dyslipidaemia was 6‐8 years earlier in males than in females. Females had higher odds than males for osteoarthritis (OR 1.33), depression (OR 2.22) or osteoporosis (OR 7.10); all P < .0001.ConclusionsMales with obesity received a diagnosis of cardiovascular risk factors at an earlier age than females, which may have contributed to the higher prevalence of coronary heart disease. Understanding sex‐specific variations in co‐morbidities across ages can support early screening and diagnosis of risk clusters for optimal obesity management.
Catheter‐related deep vein thrombosis: Where are we at and where are we going? Updates and ongoing unmet clinical needs
Authors: Girardi Laura , Di Nisio Marcello , Candeloro Matteo , Valeriani Emanuele , Ageno Walter 
Published: September 2024

AbstractBackgroundCatheter‐related thrombosis (CRT) is one of the major complications affecting patients with indwelling venous catheters, usually involving the upper extremity deep venous system. This condition can lead to potentially life‐threatening complications such as pulmonary embolism and sepsis. The risk of developing CRT varies depending on type of catheters and patient characteristics. Despite advances in materials and technologies, the actual incidence of CRT is still considerable. Available evidence on CRT management remains controversial, and clinical guidelines base their recommendations on data from non‐catheter related upper extremity or lower extremity deep venous thromboses.AimsThis narrative review aims to describe the epidemiology of CRT, to review the available evidence on its management and to highlight the current unmet needs.MethodsNo formal search strategy was applied for the revision of the literature. The main sources of information used were Medline and guidelines from international societies.ContentThe management of CRT requires a careful balance between the risk of thrombus progression, recurrent events, and systemic embolization and the increased bleeding risk in often fragile patients. Open issues include the optimal management of the catheter and the type and duration of anticoagulant therapy. Direct oral anticoagulants are increasingly prescribed, representing an important alternative to the standard of care low molecular weight heparins in selected cases. The development of new anticoagulant drugs such as factors XI and XII inhibitors may offer further advantages in this context.ConclusionsThe management of CRT is still challenging with constant need for updated evidence to support tailored approaches.
Commentary: What Is Truly Foundational?
Authors: Crespo Cruz Eduardo J. , Immanuel Aria , Keller Lisa A. , Ketan  , McIntee Kimberly , Serrano Fernando José Mena , Sireci Stephen G. , Smith Nate , Suárez‐Álvarez Javier , Wells Craig S. , Woodland Rebecca , Zenisky April L. 
Published: September 2024

AbstractThe Task Force on Foundational Competencies in Educational Measurement has produced a set of foundational competencies and invited comment on the document. The students and faculty at the University of Massachusetts Amherst provide their comments and critique of the proposed competencies. Both students and faculty agree that there needs to be more specificity regarding the purpose of the document, the nature of the data used to produce the document, and the definition of the relevant terms. Additionally, attention should be paid to the international context, and the role of artificial intelligence and machine learning. The authors acknowledge the contribution of the draft of the foundational competencies and look forward to more conversation regarding this topic.
Internal fixation of a short oblique scapular neck fracture in a foal using two 3.5‐mm tibial‐plateau‐levelling‐osteotomy (TPLO) locking plates
Authors: Marcos‐Serralta Sonia , Gray Andrew Scott 
Published: September 2024

SummaryThis case report describes a novel fixation technique of scapular neck fracture in a 2‐week‐old Arabian foal using two 3.5 mm tibial‐plateau‐levelling‐osteotomy (TPLO) locking plates originally designed for small animal orthopaedic surgery. The foal presented with a traumatic short oblique scapular neck fracture. Fracture fixation was performed under general anaesthesia using two anatomically pre‐shaped 3.5 mm TPLO locking plates; one on each side of the spine of the scapula. Fracture fixation was successful using two TPLO locking plates. Minimal soft tissue manipulation and identification of the suprascapular nerve allowed for relatively atraumatic application of the implants. The implants were left in place. Follow‐up evaluation 2 years after surgical intervention confirmed the horse to be sound with no clinical or gait abnormalities. Stabilisation of a short oblique scapular neck fracture in a 2‐week‐old foal with an anatomically pre‐shaped implant led to a good outcome in this case report. No complications were encountered during the recovery period. The use of an anatomically pre‐shaped locking plate intended for use on dogs, which is widely available in the veterinary industry, has proven to be a viable alternative for a scapular neck fracture fixation in this foal.
Development of luminescent probes for real‐time detection of the CDK/PP2A balance during the cell cycle
Authors: Hino Hirotsugu , Takaki Kaori , Kobe Mika , Mochida Satoru 
Published: September 2024

AbstractFrom a biochemical viewpoint, the cell cycle is controlled by the phosphorylation of cyclin‐dependent kinase (CDK) substrates, and the phosphorylation level is determined by the enzymatic balance between CDK and protein phosphatase 2A (PP2A). However, the conventional techniques for analyzing protein phosphorylation using radioisotopes and antibodies involve many operational steps and take days before obtaining results, making them difficult to apply to high‐throughput screening and real‐time observations. In this study, we developed luminescent probes with a light intensity that changes depending on its phosphorylation state. We modified the Nano‐lantern probe (Renilla luciferase‐based Ca2+ probe) by introducing a CDK‐substrate peptide and a phosphopeptide‐binding domain into the luciferase. Our initial trial resulted in new probes that could report the CDK/PP2A balance in a purified system. Further modifications of these probes (replacing the phospho‐Ser with phospho‐Thr and randomly replacing its surrounding amino acids) improved the dynamic range by up to four‐fold, making them practical for use in the Xenopus egg extracts system, where many physiological events can be reproduced. Taken together, our new probes enabled the monitoring of the CDK/PP2A balance in real time, and are applicable to high‐throughput systems; the new probes thus appear promising for use in substrate and drug screening.
Grupo Vivências: Rehearsing resistance to abyssal thinking in business schools
Authors: dos Santos Elisabeth Cavalcante , da Silva Ítalo , Lorêto Myrna Suely Silva 
Published: September 2024

AbstractThe objective of this study is to point out ways of resisting abyssal thinking in business schools based on the practices of the “Grupo Vivências,” a teaching, research, and extension group that originated in the business course of an academic center located in the peripheral region Agreste, in Pernambuco, a state in northeastern Brazil. The theoretical discussion in this article is anchored in the decolonial thinking developed by the Epistemologies of the South through the notions of “abyssal thinking” or “colonial thinking,” “engaged pedagogy,” and “pluriversal methodologies.” The discussion is based on the narrative of one of the group's coordinating professors and the first author of this article, which brings together different narratives referring to the practices of the Grupo Vivências, carried out between 2018 and 2022. The research and extension proposal of the group has questioned the colonial hierarchical divisions of mind versus body, theory versus practice, subject versus object, as well as knowing versus doing. Thus, the group's practices have shown resistance to abyssal/colonial thinking when: (1) they have sought to recognize the differences that make up the participants in the projects and, based on this, have elaborated possibilities of resistance to perceived oppressions mediated through the use of art; (2) they have encouraged values contrary to modern rational‐instrumental logic such as care, embracement, sharing, and collective construction; and (3) they have sought to insert the ecology of knowledge into their practices by creating spaces for dialogue between different fields of procedural knowledge.
Exploring the interplay between enjoyment, anxiety, ideal self, and willingness to communicate in EMI higher education
Authors: Xu Jian , Zhou Sihan , Chen Chen , Perrin Stuart , Gan Haiyun 
Published: September 2024

AbstractLearning academic disciplinary knowledge through English as a medium of instruction (EMI) in higher education can be emotionally taxing. However, compared to the bulk of studies investigating the role of emotions in language learning, research that explores students’ emotional experiences in EMI contexts remains scarce. Drawing on a sample of 746 undergraduate students at an EMI university in China, the present study disentangles how two heavily researched emotions (i.e., enjoyment and anxiety) affect students’ learning motivation and willingness to communicate (WTC) inside and outside of EMI classrooms. Students’ motivation is conceptualized through the notion of ideal self to represent their aspired future self‐image as competent language users (ideal L2 self) and subject experts in the field (ideal disciplinary self). Results from structural equation modeling analyses highlighted enjoyment as a strong positive predictor for both ideal selves and WTC. In contrast, anxiety failed to predict neither ideal L2 self nor ideal disciplinary self but had a negative effect on WTC. The two types of ideal selves were found to differ in their respective impact on students’ WTC inside of EMI classrooms yet neither predicted WTC outside of classrooms. Pedagogical implications for EMI teaching and learning are provided.
Introducción: La formalización del trabajo doméstico remunerado. Trayectorias actuales y retos futuros
Authors: JAEHRLING Karen , PEREYRA Francisca , POBLETE Lorena 
Published: September 2024

ResumenDesde la adopción del Convenio sobre las trabajadoras y los trabajadores domésticos, 2011 (núm. 189) de la OIT, las políticas públicas se han centrado en la formalización. Sin embargo, los avances siguen siendo lentos. Incluso cuando aumenta la cobertura jurídica en virtud de la nueva legislación laboral y de seguridad social, el control del cumplimiento suele ser insuficiente. En esta introducción al número monográfico se ahonda en las dinámicas y los factores causales que determinan la formalización efectiva, pasando por modalidades intermedias entre el trabajo informal y el formal, y se destaca la agencia de los actores (Estados, intermediarios, actores colectivos, empleadores y trabajadores) a nivel macro, meso y micro.
Associations between income/employment status and diabetes care processes, health behaviors, and health outcomes in Japan: A cross‐sectional study using claims data linked to a questionnaire survey
Authors: Yamaoka Takuya , Sugiyama Takehiro , Ihana‐Sugiyama Noriko , Kimura Akiko , Yamamoto Kouko , Imai Kenjiro , Kuroda Naoaki , Ohsugi Mitsuru , Ueki Kohjiro , Yamauchi Toshimasa , Tamiya Nanako 
Published: September 2024

ABSTRACTAims/IntroductionWe aimed to explore the associations between income/employment status and diabetes care processes, health behaviors and health outcomes.Materials and MethodsThis cross‐sectional study used health insurance claims data between April 2021 and March 2022, and a questionnaire survey between December 2022 and January 2023 in Tsukuba City. The study analyzed the participants with diabetes (other than type 1) from those selected by stratified random sampling. We evaluated diabetes care processes, health behaviors and health outcomes by calculating weighted proportions among the groups. We also assessed the associations between income/employment status and these variables using multivariable modified Poisson regression models.ResultsOf the 264 identified participants, 161 (64.2%) were men and 168 (72.8%) were aged ≥65 years old. Compared with the low‐income groups, the high‐income group had a higher proportion of sodium–glucose cotransporter 2 inhibitors or glucagon‐like peptide‐1 receptor agonists use (adjusted risk ratio [aRR] 1.70, 95% confidence interval (CI) 1.07–2.72), a higher proportion of attendance to annual health checkups for ≥2 years (aRR 1.68, 95% CI 1.07–2.64) and a lower proportion of all‐cause hospitalization (aRR 0.15, 95% CI 0.04–0.48); additionally, the middle‐income group had a lower proportion of high total outpatient medical expenses (aRR 0.57, 95% CI 0.35–0.92). Compared to the no work time group, the full‐time work group had a lower proportion of exercise habits (aRR 0.59, 95% CI 0.35–0.99) and a higher proportion of good self‐reported health (aRR 2.08, 95% CI 1.22–3.55).ConclusionsSeveral variables were associated with income/employment status. Policy intervention should focus on high‐risk groups identified by considering these associations.
Influence of acclimatization time on barometric whole‐body plethysmography in cats with lower airway disease
Authors: Hörner‐Schmid Lina , Gareis Hannah , Palić Jelena , Schulz Bianka 
Published: September 2024

AbstractBackgroundBarometric whole‐body plethysmography (BWBP) is used as a noninvasive method to assess lung function in cats with lower airway disease (LAD). The duration of the acclimatization period in the measuring chamber varies between the studies.ObjectivesTo assess the influence of acclimatization time on variables indicative of lung function.AnimalsTwenty‐four client‐owned cats with LAD and 8 healthy cats.MethodsIn the prospective case‐control study for each cat, a 30‐minute dataset was collected. Data for the three 10‐minute periods were statistically compared.ResultsThe variables pause (T1 median: 0.8, range: [0.7‐1]; T3: 0.9 [0.8‐1.1]; P ≤ .01), peak inspiratory flow (PIF; T1: 84.9 [71.6‐112.7]; T3: 75 [63.6‐108.3]; P ≤ .001), peak expiratory flow (PEF; T1: 53.2 [41.5‐76.6]; T3: 42.5 [34.6‐57.8]; P ≤ .01), and a quotient of PEF and expiratory flow at 50% expired volume (PEF/EF50; T1: 1.2 [1.1‐1.4]; T3: 1.2 [1.1‐1.5]; P ≤ .01) varied significantly between first and third time period in cats with LAD. In healthy cats PIF (T1: 76.4 [66.3‐85.2]; T2: 69.5 [58.3‐85.2]; P ≤ .01), PEF (T1: 40 [32.8‐58.6]; T2: 34.3, [29.8‐44.6]; P ≤ .01), and PEF/EF50 (T1: 13.1 [11.6‐14.6]; T3: 13.6 [12.4‐16.3]; P ≤ .01) changed significantly between first and second time period. Enhanced pause did not change significantly in either group.Conclusions and Clinical ImportanceAcclimatization time has a significant influence on multiple variables in BWBP. Manual correction of the data for tidal breathing flow‐volume loop might be necessary.