bluuebunny/crossref_metadata_2025_split huggingface dataset:
"New look" on antioxidant systems in various diabetes mellitus complications
Authors: Shemyakina Nadezhda Anatol'evna , Ermolina Alena Vladimirovna , Namokonov Evgeny Vladimirovich 
Published: February 2017

Актуальность:В настоящее время остро стоит вопрос о более ранней диагностике и прогнозировании осложнений, связанных с диабетической макро- и микроангиопатией. Раннее выявление нарушений антиоксидантной системы, которые появляются уже на стадии доклинических проявлений, позволят предотвратить или улучшить течение осложнений связанных с сахарным диабетом.Цель:Оценить состояние антиоксидантной системы у пациентов с различными сосудистыми осложнениями СД 2типа, такими как диабетическая ретинопатия (ДР) и ангиопатия сосудов нижних конечностей.Материалы и методы:В исследовании принимали участие три группы пациентов, всего 75 человек в возрасте 55±6,0лет. Первая группа пациентов (n=25) включала больных СД 2 типа (инсулиннезависимый) с наличием диабетической ретинопатии. Во второй группе пациентов (n=25), течение СД 2типа (инсулиннезависимый), протекало с развитием ангиопатии сосудов нижних конечностей. Третью группу составили 25 здоровых людей.Определение исследуемых показателей производили ВЭЖХ методами, разработанными в нашей лаборатории.Результаты исследований и обсуждение:Полученные данные свидетельствуют о том, что антиоксидантный потенциал плазмы (Cysfree/Cys-S-S-Cys) крови при сосудистых осложнениях СД 2типа уменьшается и окислительно-восстановительное состояние GSH/GSSG изменяется в зависимости от различных видов сосудистых осложнений СД 2типа.Выводы:При развитии сосудистых осложнениях СД 2типа страдает как антиоксидантный потенциал плазмы, так и непосредственно клетки, что выражается в значимом уменьшении восстановленных форм определяемых показателей.При прогрессировании заболевания и наличии диабетической ангиопатии коэффициенты Cysfree/Cys-S-S-Cys и GSH/GSSG достоверно отличаются от таковых в группе контроля. Опираясь на это, можно с уверенностью говорить о том, что у пациентов с СД 2типа необходима полная оценка антиоксидантной системы, с изучением различных фракций не только глутатиона, но и цистеина для своевременной фармакологической коррекции и профилактике преждевременного развития осложнений.Ключевые слова: цистеин, глутатион, антиоксидантная система, сахарный диабет.
REGISTRATION OF VOTERS WITHIN THE PERSPECTIVE OF CONSTITUTIONAL DEMOCRACY: CASE STUDY OF REGISTER OF VOTERS IN 2014 GENERAL ELECTION
Authors: Hoesein,SH.,MH Zainal Arifin 
Published: February 2017

<p>Voting right is citizen’s constitutional rights. There is nothing that can obscure it, not to mention negate it, as long as it is not against the moral, religious, public stability and security values. The action to negate the voting rights is an act of dismissal of democratic constitutional values. Indeed, the democratic values strongly upheld the citizens’ rights, including the voting rights. The correlation between the voting rights and the general election administration is a synergic correlation to create conducive election as mandated by the constitution. Administration role should not have been an obstacle for upholding the constitutional democratic values, rather, it becomes a filter in regulating each citizen in using their voting rights to ensure the legal certainty, either from technical aspects, which is the accurate ballot counting, or from substantive aspect that is to ensure the legal certainty in conducting the accountable general election. In deciding the voters, several things should be prioritized such as first, the administrative management of general election related to the population administration; and, second, the voting rights transformed into the List of Fixed Voters (DPT). Administrative data of population is a baseline data and the data source for establishing the List of Fixed Voters (DPT). </p>
KONSELING PERNIKAHAN BERBASIS ASMARA ( As-Sakinah, Mawaddah, Wa Rahmah )
Authors: Ahmad Nur 
Published: February 2017

<p>Keluarga merupakan sistem sosial yang alamiah dan keluarga berfungsi membentuk aturan-aturan, komunikasi serta negosiasi diantara para anggota keluarga. Ketiga fungsi keluarga ini mempunyai sejumlah implikasi terhadap perkembangan dan keberadaan para anggota keluarga. Keluarga melakukan suatu pola interaksi yang diulang-ulang melalui partisipasi seluruh anggota keluarga. Sehingga strategi konseling pernikahan yang dibangun akan membantu terpeliharanya hubungan-hubungan keluarga harmonis <em>As-Sakinah</em><em>, </em><em>Mawaddah, Wa Rahmah</em> juga dituntut untuk memodifikasi pola-pola transaksi dalam memenuhi kebutuhan keluarga yang mengalami perubahan yang didambakan. Membangun Keluarga bahagia melalui pendekatan konseling pernikahan pada dasarnya merupakan upaya untuk memperoleh kebahagiaan dan kesejahteraan hidup baik lahir maupun batin. Keluarga dibentuk untuk memadukan rasa kasih dan sayang diantara dua makhluk berlainan jenis, yang berlanjut untuk menyebarkan rasa kasih dan sayang keibuan dan keayahan terhadap seluruh anggota keluarga. Namun apa yang didambakan, apa yang diidealkan serta apa yang seharusnya dalam kenyataan tidak senantiasa berjalan mulus sebagaimana mestinya. Kebahagiaan yang diharapkan semoga dapat diraih dari bahtera kehidupan berumah tangga dan bukan sebaliknya yang kerapkali dirasakan justru kesedihan.</p><p><strong>Kata kunci : </strong>konseling pernikahan, sakinah mawaddah wa rahmah<strong></strong></p><p><strong> </strong></p><p><em>MARRIAGE COUNSELING BASED ON AS-SAKINAH MAWADDAH WA RAHMAH. The family is the natural and social system functioning family formed the rules, communication and negotiations between members of the family. The three functions of this family has a number of implications for the development and the existence of the family members. Perform a family interaction patterns that are repeated through the participation of all members of the family. So the marriage counselling strategy built will help the nurturing harmonious family relationships, As-Sakinah, Mawaddah Wa Rahmah is also required to modify the patterns of discounted rates in meeting the needs of the family experiencing the changes longed. Build happy family through marriage counselling approach is basically an attempt to gain happiness and prosperity of life in both the physical and the spiritual sense. The family was formed to integrate the feeling of love and affection between two different kinds of creatures that continues to spread compassion and mercy motherhood and fatherhood leads to all members of the family. But what longed, what diidealkan and what should be in reality does not always run smoothly properly. The expected happiness may be achieved from the ark life housekeeping and rather an often felt thus sorrow.</em></p><p><strong><em>Key Words :</em></strong><em> marriage counselling, sakinah mawaddah wa rahmah</em></p>
Las representaciones juveniles frente el amor y la violencia
Authors: Holguín Osorio Henry 
Published: February 2017

La juventud se dice que es la etapa más interesante y significativa de los seres humanos; las situaciones sociales que se viven están relacionadas en su mayoría con los encuentros afectivos. Los jóvenes buscan a las jóvenes entre ritos y en encuentros bajo la sombra de lo prohibido y lo mágico. En esos encuentros muchos de ellos nocturnos, los jóvenes inexplicablemente llaman, nombran y regalan la luna, aparece Arjona con canciones poéticas emancipadas con lenguajes confusos pero atractivos, o en los disparatados encuentros con el amor donde el blue Jean hace de la suya, en medio de cervezas con ritmos seductores.
PENGUJIAN KUALITATIF JENIS KOAGULAN DALAM BAHAN OLAH KARET
Authors: Purbaya Mili , Suwardin Didin 
Published: February 2017

Peningkatan mutu bahan olah karet (bokar) dapat dilakukan sejak awal proses pengolahan lateks menjadi bokar. Jenis koagulan merupakan salah satu parameter utama di dalam penentuan mutu bokar, selain tingkat kebersihan. Berdasarkan SNI bokar No. 06-2047-2002, koagulan yang dianjurkan untuk menggumpalkan lateks adalah asam format dan bahan penggumpal yang direkomendasikan oleh lembaga yang kredibel. Tetapi sebagian besar petani masih menggunakan koagulan non anjuran. Untuk itu perlu dilakukan suatu metode tertentu yang dapat mendeteksi bahan penggumpal bokar yang digunakan petani. Dengan metode ini, diharapkan petani akan menggunakan koagulan anjuran untuk meningkatkan mutu bokar. Dalam penelitian ini, metode yang digunakan untuk mendeteksi kandungan koagulan adalah pengujian secara kualitatif. Identifikasi dilakukan dengan cara mereaksikan serum atau air rendaman koagulum dengan pereaksi-pereaksi tertentu, kemudian diamati perubahan pada campuran yang menandakan karakteristik dari ion-ion yang terkandung di dalam koagulan. Koagulan non anjuran seperti tawas, cukapara dan pupuk TSP dapat dideteksi dengan menggunakan pereaksi : 1) BaCl2, 2) campuran pereaksi NH4Cl dan NH4OH, 3) campuran pereaksi etanol dan asam sulfat dan 4) campuran pereaksi HNO3 dan ammonium molibdate. Hasil pengujian sensistivitas menunjukkan bahwa bahan penggumpal non ajuran dapat dideteksi pada dosis minimal 50 ml/L lateks (1 g/L lateks) untuk cukapara (asam sulfat), 25 ml/L lateks (0,5 g/L lateks) untuk pupuk TSP dan 75 ml/L lateks (1,5 g/L lateks) untuk tawas dengan konsentrasi masing-masing 2 %. Pengujian kualitatif ini kemudian diaplikasikan untuk mengetahui kandungan ion pada koagulan “X”. Hasil pengujian menunjukkan bahwa koagulan “X” mengandung ion sulfat yang diduga berasal dari asam sulfat.
Neutral ISM, Lyα, and Lyman-continuum in the Nearby Starburst Haro 11*
Authors: Rivera-Thorsen T. Emil , Östlin Göran , Hayes Matthew , Puschnig Johannes 
Published: February 2017

Abstract
Star-forming galaxies are believed to be a major source of Lyman continuum (LyC) radiation responsible for reionizing the early universe. Direct observations of escaping ionizing radiation have however been sparse and with low escape fractions. In the local universe, only 10 emitters have been observed, with typical escape fractions of a few percent. The mechanisms regulating this escape need to be strongly evolving with redshift in order to account for the epoch of reionization. Gas content and star formation feedback are among the main suspects, known to both regulate neutral gas coverage and evolve with cosmic time. In this paper, we reanalyze Hubble Space Telescope (HST)-Cosmic Origins Spectrograph (COS) spectrocopy of the first detected local LyC leaker, Haro 11. We examine the connection between LyC leakage and Lyα line shape, and feedback-influenced neutral interstellar medium (ISM) properties like kinematics and gas distribution. We discuss the two extremes of an optically thin, density bounded ISM and a riddled, optically thick, ionization bounded ISM, and how Haro 11 fits into theoretical predictions. We find that the most likely ISM model is a clumpy neutral medium embedded in a highly ionized medium with a combined covering fraction of unity and a residual neutral gas column density in the ionized medium high enough to be optically thick to Lyα, but low enough to be at least partly transparent to LyC and undetected in Si ii. This suggests that star formation feedback and galaxy-scale interaction events play a major role in opening passageways for ionizing radiation through the neutral medium.
Evidence for Relativistic Disk Reflection in the Seyfert 1h Galaxy/ULIRG IRAS 05189–2524 Observed by NuSTAR and XMM-Newton
Authors: Xu Yanjun , Baloković Mislav , Walton Dominic J. , Harrison Fiona A. , García Javier A. , Koss Michael J. 
Published: February 2017

Abstract
We present a spectral analysis of the NuSTAR and XMM-Newton observations of the Seyfert 1h galaxy/ULIRG IRAS 05189–2524 taken in 2013. We find evidence for relativistic disk reflection in the broadband X-ray spectrum: a highly asymmetric broad Fe Kα emission line extending down to 3 keV and a Compton scattering component above 10 keV. Physical modeling with a self-consistent disk reflection model suggests that the accretion disk is viewed at an intermediate angle with a supersolar iron abundance, and a mild constraint can be put on the high-energy cutoff of the power-law continuum. We test the disk reflection modeling under different absorption scenarios. A rapid black hole spin is favored; however, we cannot place a model-independent tight constraint on the value. The high reflection fraction (

2.0–3.2) suggests that the coronal illuminating source is compact and close to the black hole (lying within 8.7

above the central black hole), where light-bending effects are important.
Johannes Dreyer (1500–1544) – Die Hervormer van Herford
Authors: Dreyer Wim 
Published: February 2017

During 2017, churches with roots in the 16th century Reformation look back at five centuries of reformed Christianity. Much attention is given to important leaders of the Reformation such as Luther and Calvin. However, there are many forgotten ‘heroes’ who will receive no accolades, nor will they be mentioned in any publication. In this contribution the author tells the story of dr Johannes Dreyer, the forgotten reformer of Herford in Westphalia (Germany). After giving some biographical and contextual information, Dreyer’s church order, which was published in 1534 in Wittenberg, is discussed in terms of language, structure and theological content. The conclusion is reached that the implementation of new church orders were an integral part of the reformation process as well as applying reformed doctrine to the practical situation of churches.
The Bloomsbury Companion to Contemporary Philosophy of Medicine
Authors: A. Marcum James 
Published: February 2017

A definitive and authoritative guide to a vibrant and growing discipline in current philosophy, The Bloomsbury Companion to Contemporary Philosophy of Medicine presents an overview of the issues facing contemporary philosophy of medicine, the research methods required to understand them and a trajectory for the discipline’s future.
Written by world leaders in the discipline, this companion addresses the ontological, epistemic, and methodological challenges facing philosophers of medicine today, from the debate between evidence-based and person-centered medicine, medical humanism, and gender medicine, to traditional issues such as disease, health, and clinical reasoning and decision-making. Practical and forward-looking, it also includes a detailed guide to research sources, a glossary of key terms, and an annotated bibliography, as well as an introductory survey of research methods and discussion of new research directions emerging in response to the rapid changes in modern medicine.
‘Philosophy needs medicine’, Hillel Braude argues, ‘to become more relevant’. By showing how modern medicine provides philosophers with a rich source of material for investigating issues facing contemporary society, The Bloomsbury Companion to Contemporary Philosophy of Medicine introduces the opportunities medicine offers philosophers together with the resources and skills required to contribute to contemporary debates and discussions.
Oxygen transport in epitaxial SrTiO&lt;sub&gt;3&lt;/sub&gt;/SrTi&lt;sub&gt;1 − &lt;i&gt;x&lt;/i&gt;&lt;/sub&gt;Fe&lt;sub&gt;&lt;i&gt;x&lt;/i&gt;&lt;/sub&gt;O&lt;sub&gt;3&lt;/sub&gt; multilayer stacks
Authors: Schulz Michal , Orland Timna , Mehlmann Alexander , Rothschild Avner , Fritze Holger 
Published: February 2017

Abstract. Nano-ionic materials made of strontium titanate (SrTiO3, STO) and solid solutions of strontium ferrite in STO (SrTi1 − xFexO3, STF) are grown on single crystalline STO substrates and characterized. Since STF exhibits an oxygen deficiency and, simultaneously, enables oxygen interstitial defects, a space charge area close to the STO | STF interface is present. Oxygen tracer diffusion experiments and impedance spectroscopy at temperatures from 500 to 700 °C and at oxygen partial pressure ranging from 10−3 to 10−23 bar confirm fast oxygen transport caused by enhanced ionic conductivity at the interface. There, an oxygen diffusion coefficient of 3. 4 × 10−10 m2 s−1 at 600 °C and a p type conductivity of about 360 S m−1 at 700 °C are calculated. Such structures open new options in design of nano-ionic materials for oxygen sensors and energy conversion at temperatures lower than those of conventional materials such as yttrium-doped zirconia.
Inter‐ and Intramolecular Cyclopropanations of Diazo Weinreb Amides Catalyzed by Ruthenium(II)‐Amm‐Pheox
Authors: Mandour Hamada S. A. , Chanthamath Soda , Shibatomi Kazutaka , Iwasa Seiji 
Published: February 2017

AbstractInter‐ and intramolecular cyclopropanations of a series of diazo Weinreb amides and trans‐allylic diazo Weinreb amide derivatives have been achieved using chiral ruthenium(II)‐Amm‐Pheox catalyst to give the corresponding chiral cyclopropyl Weinreb amides in excellent yield (up to 99%) with excellent enantioselectivity (up to 99% ee). The chiral products could easily undergo useful synthetic transformations to give the corresponding aldehydes, alcohols and ketones in high yields and enantioselectivities.magnified image
Cu submicroparticles catalyzed reduction of 3‐nitro‐4‐methoxyacetanilide to 3‐amino‐4‐methoxyacetanilide in water
Authors: Feng Yonghai , Yin Hengbo , Yan Xiaobo , Meng Minjia , Mi Jianli , Wang Aili 
Published: February 2017

Abstract3‐nitro‐4‐methoxy acetanilide (NMA) was selectively reduced to 3‐amino‐4‐methoxy acetanilides (AMA) with metallic Cu submicroparticles as the H‐transfer catalyst in NaBH4 solution. The metallic Cu submicroparticles were prepared by the wet chemical reduction method and characterized by SEM, XRD, and XPS techniques. The catalytic activity of Cu submicroparticles in the reduction of NMA was significantly affected by the particle sizes of Cu submicroparticles. The catalyst of Cu submicroparticles with an average particle size of 0.36 µm contributes to an AMA selectivity of 96.1 % at the NMA conversion of 100 % after reacting at 303 K for 40 min. The Cu submicroparticles show better catalytic activities than the Cu microparticles in the reduction of NMA to AMA probably due to the low reaction orders and the low activation energy of Cu submicroparticles for the reduction of NMA.
Nickel‐Promoted Oxidative ipso‐Annulation of N‐(p‐Methoxyaryl)propiolamides with α‐Carbonyl Alkyl Bromides
Authors: Li Meng , Song Ren‐Jie , Li Jin‐Heng 
Published: February 2017

AbstractA new route to producing 3‐alkyl spiro[4,5]trienones via nickel‐promoted radical oxidative ipso‐annulation of N‐(p‐methoxyaryl)propiolamides with α‐carbonyl alkyl bromides using TBHP oxidant is described. The method allows the formation of three new C—C bonds through a sequence of oxidative C—Br bond cleavage, ipso‐cyclization and dearomatization, and represents a new alkyne 1,2‐difunctionalization to access to the construction of spiro[4,5]trienones.
Intravoxel incoherent motion MRI assessment of chemoradiation‐induced pelvic bone marrow changes in cervical cancer and correlation with hematological toxicity
Authors: Lee Elaine Yuen Phin , Perucho Jose Angelo Udal , Vardhanabhuti Vince , He Jian , Siu Steven Wai Kwan , Ngu Siew Fei , Mayr Nina A. , Yuh William T.C. , Chan Queenie , Khong Pek‐Lan 
Published: February 2017

PurposeTo investigate bone marrow changes after chemoradiation (CRT) using intravoxel incoherent motion magnetic resonance imaging (IVIM‐MRI) and correlate imaging changes with hematological toxicity (HT) in patients with locally advanced cervical cancer.Materials and MethodsThirty‐nine patients with newly diagnosed cervical cancer were prospectively recruited for two sequential 3.0T IVIM‐MRI studies: before treatment (MRI‐1) and 3–4 weeks after standardized CRT (MRI‐2). The irradiated pelvic bone marrow was outlined as the regions of interest to derive the true diffusion coefficient (D) and perfusion fraction (f) based on a biexponential model. The apparent coefficient diffusion (ADC) was derived using the monoexponential model. Changes in these parameters between MRI‐1 and MRI‐2 were calculated as ΔD, Δf, and ΔADC. HT was defined accordingly to NCI‐CTCAE (v. 4.03) of grade 3 and above. Statistical analysis was performed using Mann–Whitney U‐test.ResultsThe median age of patients was 54 years old (range 27–83 years old); 14 patients suffered from HT. Early bone marrow changes (3–4 weeks) of ΔD showed a significant difference between HT and non‐HT groups (6.4 ± 19.7% vs. –6.4 ± 19.4%, respectively, P = 0.041). However, no significant changes were noted in Δf (3.7 ± 13.3% vs. 1.5 ± 12.5% respectively, P = 0. 592) and ΔADC (5.5 ± 26.3% vs. –3.3 ± 27.0% respectively, P = 0.303) between the HT and non‐HT groups. Δf increased insignificantly for both groups.ConclusionΔD was the only significant parameter to differentiate early cellular environment changes in bone marrow after CRT, suggestive that ΔD was more sensitive than Δf and ΔADC to reflect the underlying microenvironment injury.Level of Evidence: 2Technical Efficacy: Stage 1J. Magn. Reson. Imaging 2017;46:1491–1498.
Semiconductor optical amplifiers at 2.0‐µm wavelength on silicon
Authors: Volet Nicolas , Spott Alexander , Stanton Eric J. , Davenport Michael L. , Chang Lin , Peters Jon D. , Briles Travis C. , Vurgaftman Igor , Meyer Jerry R. , Bowers John E. 
Published: February 2017

AbstractA semiconductor optical amplifier at 2.0‐µm wavelength is reported. This device is heterogeneously integrated by directly bonding an InP‐based active region to a silicon substrate. It is therefore compatible with low‐cost and high‐volume fabrication infrastructures, and can be efficiently coupled to other active and passive devices in a photonic integrated circuit. On‐chip gain larger than 13 dB is demonstrated at 20 °C, with a 3‐dB bandwidth of ∼75 nm centered at 2.01 µm. No saturation of the gain is observed for an on‐chip input power up to 0 dBm, and on‐chip gain is observed for temperatures up to at least 50 °C. This technology paves the way to chip‐level applications for optical communication, industrial or medical monitoring, and non‐linear optics.
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Gluteal compartment syndrome with neurologic impairment: Report of 2 cases and review of the literature
Authors: Kuhlman Greg D. , Gwathmey Kelly G. 
Published: February 2017

ABSTRACTIntroduction: We describe two patients who developed gluteal compartment syndrome (GCS) in the context of drug overdose. One patient developed a sciatic neuropathy, and one patient developed a lumbosacral plexopathy. Methods: We reviewed the literature of atraumatic GCS and resultant neurological impairment. Results: We reviewed 26 cases (our two cases and 24 previously published cases) of GCS and neurological impairment. All patients developed GCS in the context of drug or alcohol overdose. Creatine kinase was markedly elevated in all patients in which it was tested, and most patients developed renal failure. Seventeen patients had a fasciotomy, and 9 patients were managed conservatively. There appeared to be a trend toward worse prognosis in the conservatively managed group. Discussion: Neurologists should be aware of GCS. Immediate recognition facilitates consideration of further diagnostic testing, including intracompartmental pressure measurement and consideration of surgical decompression, which may influence outcome. Muscle Nerve, 57: 325–330, 2018
Delivery of radiation therapy in resource‐limited settings: A pilot quality assessment study
Authors: Power‐Hays Alexandra , Friedrich Paola , Fernandez Gretchen , Cruz Naly A. , Marcus Karen , Rodriguez‐Galindo Carlos , Collado Luisa 
Published: February 2017

AbstractProgress has been made in resource‐limited countries in treating acute lymphoblastic leukemia, but advances in solid malignancies have been slower. Multidisciplinary care coordination is challenging, assessing adherence to guidelines through quality improvement initiatives is essential. We characterized deviations from guidelines in the delivery of radiation in a middle‐income country program as a pilot for evaluating adequacy of local control and as surrogate for integration of multidisciplinary care. One‐third of patients for whom it was indicated did not receive radiation. Of the patients who received radiation, 95% had a deviation. This study underscores the importance of quality assessment in resource‐limited settings.