bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diglycolamic acid anchored on polyamine matrix for the mutual separation of Eu(III) and Am(III)
Authors: Suneesh A. S. , Syamala K. V. , Venkatesan K. A. , Antony M. P. , Vasudeva Rao P. R. 
Published: January 2016

Abstract
Diglycolamic acid was anchored on a polyamine matrix and the product
(PA-DGAH) was characterized by ion-exchange capacity measurement,
TG-DTA and FT-IR spectroscopy. The extraction behavior of
Am(III) and Eu(III) in PA-DGAH was studied from dilute
nitric acid medium to examine the feasibility using the anchored
adsorbent for their mutual separation. The effect of various
parameters such as the duration of equilibration, concentration of
europium, nitric acid and diethylenetriaminepentaacetic acid (DTPA) in
aqueous phase on the distribution coefficient (K
d) of
Am(III) and Eu(III) was studied. The distribution
coefficient decreased with increase in the concentration of nitric
acid. Rapid extraction of metal ions in the initial stages of
equilibration followed by the establishment of equilibrium occurred
within 4 h. The data on the rate of uptake of
Am(III) and Eu(III) were fitted into pseudo-first order
and pseudo-second order rate equation. The extraction isotherm was
fitted to Langmuir and Freundlich adsorption models and the apparent
europium extraction capacity was determined. The mechanism of
extraction was elucidated and the conditions needed for efficient
separation of Am(III) from Eu(III) was optimized using
DTPA. The study indicated the possibility of using PA-DGAH for the
separation of Eu(III) from Am(III) with high separation
factors.
Primary central nervous system lymphoma: is absence of intratumoral hemorrhage a characteristic finding on MRI?
Authors: Sakata Akihiko , Okada Tomohisa , Yamamoto Akira , Kanagaki Mitsunori , Fushimi Yasutaka , Dodo Toshiki , Arakawa Yoshiki , Takahashi Jun C , Miyamoto Susumu , Togashi Kaori 
Published: January 2016

Abstract
Background. Previous studies have shown that intratumoral hemorrhage is a common finding in glioblastoma multiforme, but is rarely observed in primary central nervous system lymphoma. Our aim was to reevaluate whether intratumoral hemorrhage observed on T2-weighted imaging (T2WI) as gross intratumoral hemorrhage and on susceptibilityweighted imaging as intratumoral susceptibility signal can differentiate primary central nervous system lymphoma from glioblastoma multiforme.
Patients and methods. A retrospective cohort of brain tumors from August 2008 to March 2013 was searched, and 58 patients (19 with primary central nervous system lymphoma, 39 with glioblastoma multiforme) satisfied the inclusion criteria. Absence of gross intratumoral hemorrhage was examined on T2WI, and an intratumoral susceptibility signal was graded using a 3-point scale on susceptibility-weighted imaging. Results were compared between primary central nervous system lymphoma and glioblastoma multiforme, and values of P < 0.05 were considered significant.
Results. Gross intratumoral hemorrhage on T2WI was absent in 15 patients (79%) with primary central nervous system lymphoma and 23 patients (59%) with glioblastoma multiforme. Absence of gross intratumoral hemorrhage could not differentiate between the two disorders (P = 0.20). However, intratumoral susceptibility signal grade 1 or 2 was diagnostic of primary central nervous system lymphoma with 78.9% sensitivity and 66.7% specificity (P < 0.001), irrespective of gross intratumoral hemorrhage.
Conclusions. Low intratumoral susceptibility signal grades can differentiate primary central nervous system lymphoma from glioblastoma multiforme. However, specificity in this study was relatively low, and primary central nervous system lymphoma cannot be excluded based solely on the presence of an intratumoral susceptibility signal.
Doppler ultrasound for diagnosis of soft tissue sarcoma: efficacy of ultrasound-based screening score
Authors: Nagano Satoshi , Yahiro Yuhei , Yokouchi Masahiro , Setoguchi Takao , Ishidou Yasuhiro , Sasaki Hiromi , Shimada Hirofumi , Kawamura Ichiro , Komiya Setsuro 
Published: January 2016

Abstract
Background. The utility of ultrasound imaging in the screening of soft-part tumours (SPTs) has been reported. We classified SPTs according to their blood flow pattern on Doppler ultrasound and re-evaluated the efficacy of this imaging modality as a screening method. Additionally, we combined Doppler ultrasound with several values to improve the diagnostic efficacy and to establish a new diagnostic tool.
Patients and methods. This study included 189 cases of pathologically confirmed SPTs (122 cases of benign disease including SPTs and tumour-like lesions and 67 cases of malignant SPTs). Ultrasound imaging included evaluation of vascularity by colour Doppler. We established a scoring system to more effectively differentiate malignant from benign SPTs (ultrasound-based sarcoma screening [USS] score).
Results. The mean scores in the benign and malignant groups were 1.47 ± 0.93 and 3.42 ± 1.30, respectively. Patients with malignant masses showed significantly higher USS scores than did those with benign masses (p < 1 × 10-10). The area under the curve was 0.88 by receiver operating characteristic (ROC) analysis. Based on the cut-off value (3 points) calculated by ROC curve analysis, the sensitivity and specificity for a diagnosis of malignant SPT was 85.1% and 86.9%, respectively.
Conclusions. Assessment of vascularity by Doppler ultrasound alone is insufficient for differentiation between benign and malignant SPTs. Preoperative diagnosis of most SPTs is possible by combining our USS score with characteristic clinical and magnetic resonance imaging findings.
Evaluation of radiographic and metabolic changes in bone metastases in response to systemic therapy with 18FDG-PET/CT
Authors: Gunalp Bengul , Oner Ali Ozan , Ince Semra , Alagoz Engin , Ayan Aslı , Arslan Nuri 
Published: January 2016

Abstract
Background. The aim of the study was to retrospectively evaluate radiographic and metabolic changes in bone metastases in response to systemic therapy with 18FDG-PET/CT and determine their roles on the evaluation of therapy response.
Patients and methods. We retrospectively evaluated radiographic and metabolic characteristics of bone metastases in 30 patients who were referred for the evaluation of response to systemic therapy with 18FDG-PET/CT. All patients underwent integrated 18FDG-PET/CT before and after treatment.
Results. The baseline radiographic patterns of the target lesions in responders group were lytic, sclerotic, mixed and CT negative; after treatment the radiographic patterns of all target lesions changed to a sclerotic pattern and attenuation increased (p = 0.012) and metabolic activity decreased (p = 0.012). A correlation was found between decreasing metabolic activity and increasing attenuation of the target lesions (r = -0.55) (p = 0.026). Ho wever, in nonresponders group, the baseline radiologic patterns of the target lesions were lytic, blastic, mixed and CT negative; after treatment all lytic target lesions remained the same and one CT negative lesion turned to lytic pattern and the attenuation of the target lesions decreased (p ± 0.12) and metabolic activity increased (p = 0.012). A correlation was found between increasing metabolic activity and decreasing attenuation (r = -0.65) (p = 0.032). An exception of this rule was seen in baseline blastic metastases which progressed with increasing in size, metabolic activity and attenuation.
Conclusions. This study shows that the metabolic activity of lesions is a more reliable parameter than the radiographic patterns for the evaluation of therapy response.
Feasibility and safety of electrochemotherapy (ECT) in the pancreas: a pre-clinical investigation
Authors: Girelli Roberto , Prejanò Simona , Cataldo Ivana , Corbo Vincenzo , Martini Lucia , Scarpa Aldo , Claudio Bassi 
Published: January 2016

Abstract
Background. Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease generally refractory to standard chemotherapeutic agents; therefore improvements in anticancer therapies are mandatory. A major determinant of therapeutic resistance in PDAC is the poor drug delivery to neoplastic cells, mainly due to an extensive fibrotic reaction. Electroporation can be used in vivo to increase cancer cells’ local uptake of chemotherapeutics (electrochemotherapy, ECT), thus leading to an enhanced tumour response rate. In the present study, we evaluated the in vivo effects of reversible electroporation in normal pancreas in a rabbit experimental model. We also tested the effect of electroporation on pancreatic cancer cell lines in order to evaluate their increased sensitivity to chemotherapeutic agents.
Materials and methods. The application in vivo of the European Standard Operating Procedure of Electrochemotherapy (ESOPE) pulse protocol (1000 V/cm, 8 pulses, 100 μs, 5 KHz) was tested on the pancreas of normal New Zealand White Rabbits and short and long-term toxicity were assessed. PANC1 and MiaPaCa2 cell lines were tested for in vitro electrochemotherapy experiments with and without electroporation. Levels of cell permeabilization were determined by flow cytometry, whereas cell viability and drug (cisplatin and bleomycin) sensitivity of pulsed cells were measured by 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium (MTS) assay.
Results. In healthy rabbits, neither systemic nor local toxic effects due to the electroporation procedure were observed, demonstrating the safety of the optimized electric parameters in the treatment of the pancreas in vivo. In parallel, we established an optimized protocol for ECT in vitro that determined an enhanced anti-cancer effect of bleomycin and cisplatin with respect to treatment without electroporation.
Conclusions. Our data suggest that electroporation is a safe procedure in the treatment of PDAC because it does not affect normal pancreatic parenchyma, but has a potentiating effect on cytotoxicity of bleomycin in pancreatic tumour cell lines. Therefore, ECT could be considered as a valid alternative for the local control of non-resectable pancreatic cancer.
3 Baruch Revisited: Jewish or Christian Composition, and Why It Matters
Authors: Himmelfarb Martha 
Published: January 2016

AbstractIn his important 1976 paper, “The Pseudepigrapha in Christianity,” Robert A. Kraft insists that scholars of ancient Judaism and Christianity need to take full account of the Christian contexts in which so-called Old Testament pseudpigrapha have come down to us before attempting to make the case that a text preserved only in late manuscripts in languages used primarily or exclusively by Christians reflects a Jewish original of the Second Temple period. The end result, Kraft admitted, is likely to be a smaller library of Jewish works from the turn of the era. This paper discusses 3 Baruch, an apocalypse that most scholars have treated as originally Jewish despite, in addition to its preservation by Christians, certain features quite unusual in Jewish works, as a test case. It argues that recent scholarship has failed to give adequate weight to Kraft’s crucial insights and suggests that scholarly accounts of diaspora Judaism in the Second Temple period would look rather different if those insights were taken more seriously. Finally it offers some tentative suggestions about a Christian setting in which 3 Baruch might have been composed.
Edfu and the Oriens: On Re-discovering Ancient Egyptian Lore in Two Coptic Apocalypses
Authors: Tripaldi Daniele 
Published: January 2016

AbstractThe article attempts to examine anew two classical cases of alleged continuity of ancient Egyptian traditions into Coptic Late Antique and its literature. Formal correspondences are sought, possible channels of transmission are surveyed and discussed, the explanatory potential of the identified survivals is ascertained. A few concluding remarks on detecting and reconstructing transfers of knowledge in and through literary texts are finally added.
Menyoal Kebebasan Beragama dan Penodaan Agama Di Indonesia
Authors: Sopyan Yayan 
Published: January 2016

Abstract: Questioning the Religious Freedom and blasphemy in Indonesia. The presence of the Constitutional Court in the reform era is the strengthening of the foundations of constitutionalism in the Constitution of the Republic of Indonesia Year 1945. The Court in this case a role to enforce and the protector of the citizen's constitutional rights and the protector of the human rights. Including in this case, the right to religion and religious practices and teachings of their respective religions, in accordance with the constitutional mandate. However, on the other hand there is the discourse of freedom of expression and freedom of speech includes freedom to broadcast religious beliefs and understanding of the "deviant" and against the "mainstream" religious beliefs and understanding in general, as in the case of Ahmadiyah. The Court in this case is required to provide the best attitude when faced judicial review in this case still required in addition to guarding the constitution in order to run properly. Abstrak: Menyoal Kebebasan Beragama dan Penodaan Agama di Indonesia. Kehadiran lembaga Mahkamah Konstitusi di era reformasi merupakan upaya penguatan terhadap dasar-dasar konstitusionalisme pada Undang-Undang Dasar Negara Republik Indonesia Tahun 1945. MK dalam hal ini berperan menegakkan dan melindungi hak-hak konstitusional warga negara (the protector of the citizen’s constitutional rights) dan pelindung HAM (the protector of the human rights). Termasuk dalam hal ini, hak untuk memeluk agama dan menjalankan ibadah serta ajaran agamanya masing-masing, sesuai dengan amanat konstitusi. Namun, disisi lain ada wacana kebebasan berekspresi dan kebebasan berpendapat termasuk didalamnya kebebasan untuk menyiarkan keyakinan dan pemahaman keagamaan yang “menyimpang” dan bertentangan dengan “mainstream” keyakinan dan pemahaman keagamaan pada umumnya, seperti dalam kasus Ahmadiyah. MK dalam hal ini dituntut untuk mampu memberikan sikap terbaik saat dihadapkan judicial review dalam kasus ini selain tetap dituntut untuk mengawal konstitusi agar dapat berjalan sebagaimana mestinya. DOI: 10.15408/jch.v2i2.2314
Peran Organisasi Regional Dalam Pemeliharaan Perdamaian dan Keamanan Internasional
Authors: Mulyana Imam 
Published: January 2016

Abstract: International law has stipulated a number of mechanisms in order to resolve the dispute between the countries. International dispute settlement mechanisms are required to use peaceful means as the main approach. However, if peaceful means can not resolve a dispute, it can also be used enforcementaction by the UN Security Council, particularly if potentially threatens peace and international security. The UN Charter also regulates the role of regional organizations, including when regional organizations intend to play a role related with maintenance of international peace and security. Although in practice today of regional organizations has been actively engaged in the maintenance of international peace and security, but international regulations regarding this activity has not been clearly settle, particularly in terms of scale and responsibility mechanism. Abstrak: Peran Organisasi Regional Dalam Pemeliharaan Perdamaian dan Keamanan Internasional. Hukum internasional telah mengatur sejumlah mekanisme dalam rangka menyelesaiakan sengketa yang terjadi antara negara-negara di dunia. Mekanisme penyelesaian sengketa internasional diharuskan menggunakan cara-cara damai sebagai pendekatan utama. Meskipun demikian apabila cara-cara damai tidak dapat menyelesaikan suatu sengketa, maka dapat pula digunakan cara-cara kekerasan oleh Dewan Keamanan PBB, terutama apabila mengancam perdamaian dan keamanan internasional. Piagam PBB juga mengatur mengenai peran Organisasi Regional termasuk apabila Organisasi Regional bermaksud berperan dalam melakukan pemeliharaan perdamaian dan keamanan internasional. Meskipun pada praktiknya hari ini Organisasi Regional telah aktif melakukan kegiatan pemeliharaan perdamaian dan keamanan internasional, akan tetapi ketentuan internasional mengenai aktivitas ini belum secara jelas diatur, terutama dalam hal skala dan mekanisme pertangungjawabannya. DOI: 10.15408/jch.v2i2.2317
Urgensi Pembentukan Pengadilan Khusus Agraria
Authors: Sulatri Endah , Dewa Teguh Triesna 
Published: January 2016

Jika suatu negara tanpa adanya demokrasi dan Rule f Law mungkin dapat menikmati kemakmuran, namun adalah juga benar jika suatu negara tanpa adanya demokrasi dan Rule of Law sudah pasti tidak akan menikmati keadilan Dalam kerangka hukum internasional, Universal Declaration of Human Rights tahun 1948, telah dikukuhkan perjanjian internasional (1996) mengenai Hak-Hak Ekonomi, Sosial, dan Budaya (HESB). Pasal 11 ayat 2 dari HESB mengisyaratkan bahwa sebuah Negara yang mengabaikan reformasi agraria, dianggap telah melakukan pelanggaran Hak Asasi Manusia (“HAM”). Berangkat dari pemikiran global tersebutReformasi Agraria juga menjadisebuah agenda penting yang tidak dapat diabaikan termasukIndonesia selaku negara yang menjunjung tinggi nilai-nilai HAM Dalam Pasal 1 ayat (2) Undang-Undang No. 5 Tahun 1960 tentang Peraturan Dasar Pokok-Pokok Agraria (“UU 5/1960”) disebutkan bahwa pengertian agraria secara luas menyebutkan bahwa “seluruh bumi, air, dan ruang angkasa, termasuk kekayaan alam yang terkandung di dalamnya dalam Wilayah Republik Indonesia sebagai karunia Tuhan Yang Maha Esa adalah bumi, air dan ruang angkasa bangsa Indonesia dan merupakan kekayaan nasional”. Sedangkan menurut doktrin,Subekti menyatakan “Hukum agraria adalah keseluruhan daripada ketentuan-ketentuan hukum, baik hukum perdata, maupun hukum tata negara maupun pula tata usaha negara yang mengatur hubungan-hubungan antara orang termasuk badan hukum, dengan bumi, air, dan ruang angkasa dalam seluruh wilayah neagara dan mengatur pula wewenang-wewenang yang bersumber pada hubungan-hubungan tersebut”. Dari pengertian di atas agraria memiliki dimensi yang sangat luas dan tidak hanya terbatas pada permasalahan tanah. Dalam bukunya Prof. Boedi Harsono menyatakan bahwa hukum agraria bukan merupakan satu perangkat bidang hukum melainkan sekelompok perangkat bidang hukum. Namun dalam kenyataannya hukum tanah memiliki porsi yang lebih besar dan begitu kompleks dibandingkan dengan perangkat hukum yang lain seperti hukum pertambangan, air, perikanan, dan lain-lain. DOI: 10.15408/jch.v2i2.2321
Peran Otoritas Jasa Keuangan Terhadap Pengawasan Pendaftaran Jaminan Fidusia
Authors: Tunisa Nazia 
Published: January 2016

Dalam pertumbuhan ekonomi dan teknologi saat ini, masyarakat dituntut cepat dan produktif untuk memenuhi kebutuhan (needs) dan keinginannya (wants) seperti moda transportasi yakni motor dan mobil. Hal ini menjadikan kendaraan sebagai kebutuhan mendasar bagi masyarakat (basic need). Konsep kendaraan sekarang ini telah mengalami pergeseran tidak hanya sebagai kebutuhan dasar saja, namun sebagai alat penunjang kegiatan usaha. Namun saat ini, kendaraan juga telah menjadi gaya hidup (life style), memberikan kemudahan dan menunjukkan karakteristik serta kelas sosial. Kelebihan-kelebihan atas sesuatu produk mendorong masyarakat (konsumen) tergiur untuk memilikinya meskipun secara kemampuan dana (financial) untuk membelinya tidak mencukupi. Oleh karena itu dibutuhkan lembaga yang mampu untuk menjamin terhadap selera masyarakat. Kondisi seperti ini yang menyebabkan tumbuh dan berkembangnya lembaga pembiayaan konsumen dalam sektor Lembaga Keuangan Non-Bank, selain lembaga pembiayaan yang termasuk dalam Lembaga Keuangan Non-Bank adalah asuransi, pegadaian, dana pensiun, reksa dana, bursa efek dan lain-lain. DOI: 10.15408/jch.v2i2.2325
Sistem Koordinasi Antara Otoritas Jasa Keuangan (OJK) Dengan Lembaga Penjamin Simpanan (LPS)
Authors: Windiantika Wiwin Wintarsih 
Published: January 2016

Abstract: Coordinating System Between Financial Services Authority (OJK) And Deposit Insurance Agency (LPS) In Handling Failed Bank. The Deposit Insurance Agency (LPS) is an institution that is independent, transparent and accountable in implementing its duties and authorities. Procedurally, if the Financial Services Authority (OJK) indicate a bank that is experiencing liquidity problems, OJK immediately inform the Bank of Indonesia (BI) to take steps in accordance with BI's authority. In practise, OJK coordinate with BI to make regulatory supervision in banking sector. Coordination in handling between failed banks between the LPS and OJK is shown by a confirmation from OJK to the LPS about troubled banks that are in the restructuring efforts by OJK, then LPS investigate the banks. The LPS as an institution that checks condition of banks surely will review and determine whether the troubled banks will be saved or not saved. Keywords: Financial Services Authority, Coordination System and The Deposit Insurance Agency Abstrak: Sistem Koordinasi Antara Otoritas Jasa Keuangan (OJK) Dengan Lembaga Penjamin Simpanan (LPS) Dalam Penanganan Bank Gagal. LPS adalah suatu lembaga yang independen, transparan dan akuntabel dalam melaksanakan tugas dan wewenangnya. Secara prosedur, jika OJK mengindikasikan suatu bank sedang mengalami kesulitan likuiditas dan/atau kondisi kesehatan memburuk, maka OJK segera menginformasikannya kepada Bank Indonesia (BI) untuk melakukan langkah-langkah sesuai dengan wewenang BI. Dalam pelaksanaannya, Koordinasi penanganan bank gagal antara LPS dengan OJK diperlihatkan oleh adanya konfirmasi yang dilakukan OJK kepada LPS mengenai bank bermasalah yang sedang dalam upaya penyehatan oleh OJK, kemudian LPS melakukan pemeriksaan terhadap bank terkait. LPS sudah tentu akan melakukan kajian dan memutuskan apakah bank yang sedang bermasalah tersebut akan diselamatkan atau tidak diselamatkan. DOI: 10.15408/jch.v2i2.2326
La historia contemporánea en Francia
Authors: Dosse François 
Published: January 2016

<p>La escuela de los Annales entra en crisis a partir de los años ochenta. Como respuesta, retoma a la historia política, biográfica y al individuo, a la identidad nacional francesa y la formación de la historia social sobre bases renovadas. Existe una crisis de identidad en la historia en pos de su objeto y de la singularidad de sus procedimientos. El repliego del historiador sobre el individuo indica crisis en la idea misma de historicidad, que condujo al historiador a una poshistoria que interpreta desde una perspectiva genealógica</p>
Reseña del libro: El fusil y el olivo: la cuestión militar en Centroamérica, Aguilar, Gabriel
Authors: Rodríguez de Ita Guadalupe 
Published: January 2016

<p>Análisis sobre las fuerzas armadas en Centroamérica en la década de los ochenta. Reúne seis trabajos que presentan un eje común: la trilogía fuerzas armadas, guerra y democracia. Destaca la relación entre la sociedad, el ejercicio del poder y los agentes externos en los conflictos armados de la región.</p>
El concepto de espacio y el análisis regional
Authors: Hiernaux N. Daniel , Lindon Alicia 
Published: January 2016

<p>Revisión sobre las principales conceptualizaciones del espacio bajo diferentes perspectivas disciplinarias (filosofía, economía y geografía). Se parte de niveles de mayor generalización para descender a los conceptos más específicos, por lo que se presentan tres perspectivas distintas que corresponden a categorías generales, a fin de determinar cuál puede ser mejor para el análisis regional, en la inteligencia de que este análisis debe comprender los efectos de la diferenciación espacial.</p>
El ritmo de la historia y la región
Authors: Lameiras José 
Published: January 2016

<p>Los estudios regionales ameritan una teorización del problema. Para delimitar una región es menester definir el espacio y el tiempo. Diversas disciplinas con sus propias metodologías precisaran su marco de referencia para que las vivencias cotidianas trasciendan a los espacios sociales. La región como la historia posee un ritmo, que el autor asocia a las melodías.</p>