bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autophagy in the pancreatic islets after the administration of cladribine in accordance to two different modes of therapy
Authors: Jasinski Ludwik , Lis-Sochocka Marta , Chylinska-Wrzos Patrycja , Wawryk-Gawda Ewelina , Jodlowska-Jedrych Barbara 
Published: November 2017

Abstract
The treatment of neoplastic and neurodegenerative diseases is still difficult. This because the cytostatic drugs have adverse effects on healthy organs. Among the drugs that have been investigated in the therapy of cancers and multiple sclerosis are the purine analogues. The aim of our study was the evaluation of the effect of cladribine on the process of autophagy in the healthy pancreas via two dosage models. The experiment was conducted on female Wistar rats which were placed within the experimental and control groups of two dosage models: model (A) - cladribine being administered in a daily dose of 0.1 mg/kg by weight for 7 days, and model (B) - cladribine being administered in a daily dose of 0.07 mg/kg by weight in 3 cycles of 6 days with 5 weeks break. A-bis and B-bis groups were included within, respectively, groups A and B. Here, decapitation occurred after 4 weeks break in drug administration. In our work, autophagy was investigated via the expression of the LC3B protein (Light Chain 3B protein). The comparison of the results of many independent trials was built upon the use of the Kruskal-Wallis non-parametric test. Significance was set at p < 0.005. In our results, average LC3B expression was observed in 100% of all cells in the group A, 70% in group B and 60% in group B-bis. We not observed average LC3B expression in the other groups. Moreover, a poor reaction was observed in 55% of all cells in group A-bis. We noted significant relationships between control group and group A, between the control group and group B, and between group A-bis and groups B and B-bis. These results demonstrate that cladribine has led to the induction of autophagy in the pancreatic islet cells.
Annotating Speaker Stance in Discourse: The Brexit Blog Corpus
Authors: Simaki Vasiliki , Paradis Carita , Skeppstedt Maria , Sahlgren Magnus , Kucher Kostiantyn , Kerren Andreas 
Published: November 2017

AbstractThe aim of this study is to explore the possibility of identifying speaker stance in discourse, provide an analytical resource for it and an evaluation of the level of agreement across speakers. We also explore to what extent language users agree about what kind of stances are expressed in natural language use or whether their interpretations diverge. In order to perform this task, a comprehensive cognitive-functional framework of ten stance categories was developed based on previous work on speaker stance in the literature. A corpus of opinionated texts was compiled, the Brexit Blog Corpus (BBC). An analytical protocol and interface (Active Learning and Visual Analytics) for the annotations was set up and the data were independently annotated by two annotators. The annotation procedure, the annotation agreements and the co-occurrence of more than one stance in the utterances are described and discussed. The careful, analytical annotation process has returned satisfactory inter- and intra-annotation agreement scores, resulting in a gold standard corpus, the final version of the BBC.
Simplified Generalized Gauss–Newton Method for Nonlinear Ill-Posed Operator Equations in Hilbert Scales
Authors: Mahale Pallavi , Dadsena Pradeep Kumar 
Published: November 2017

Abstract
In this paper, we study the simplified generalized Gauss–Newton method in a Hilbert scale setting to get an approximate solution of the ill-posed operator equation of the form

F
⁢

(
x
)

=
y

{F(x)=y}

where

F
:

D
⁢

(
F
)

⊆
X
→
Y

{F:D(F)\subseteq X\to Y}

is a nonlinear operator between Hilbert spaces X and Y. Under suitable nonlinearly conditions on F, we obtain an order optimal error estimate under the Morozov type stopping rule.
The Chern character of the Verlinde bundle over
ℳ¯
g,n
Authors: Marian Alina , Oprea Dragos , Pandharipande Rahul , Pixton Aaron , Zvonkine Dimitri 
Published: November 2017

Abstract
We prove an explicit formula for the total Chern character of the Verlinde bundle of conformal blocks over

ℳ
¯

g
,
n

\overline{\mathcal{M}}_{g,n}

in terms of tautological classes. The Chern characters of the Verlinde bundles define a semisimple CohFT (the ranks, given by the Verlinde formula, determine a semisimple fusion algebra). According to Teleman’s classification of semisimple CohFTs, there exists an element of Givental’s group
transforming the fusion algebra into the CohFT. We determine the element using the first Chern class of the Verlinde bundle on the interior

ℳ

g
,
n

{\mathcal{M}}_{g,n}

and the projective flatness of the Hitchin connection.
Mechanochemically synthesized LiAlOx catalyst for aqueous aldol condensation of furfural with acetone
Authors: Stepanova L. N. , Mironenko R. M. , Belskaya O. B. , Likholobov V. A. 
Published: November 2017

AbstractIn the present study, the mechanochemical method is proposed for synthesis of LiAl-layered double hydroxides (LDHs). This method is eco-friendly and allows obtaining LiAl-LDH under relatively mild conditions (centripetal acceleration of milling bodies 300 m s-2) and in a short period of time (15 minutes). The structures of as-prepared LiAl-LDH, LiAl-mixed oxide (calcined LDH) and “activated” LiAl-LDH obtained after rehydration of the corresponding mixed oxide were confirmed by X-ray diffraction. The basicity of LiAlOx was measured by temperature-programmed desorption of CO2 and double isotherm technique. According to data obtained, LiAl-mixed oxide has a significant higher carbon dioxide adsorption capacity compared to MgAlmixed oxides prepared by conventional co-precipitation method. This indicates a large amount of basic surface sites with different strength (strong, medium and weak) for Li-containing systems. The formation of “activated” LiAl-LDH having Bronsted basic sites (OH groups in the interlayer space) provides an increased catalytic activity of LiAlOx in the reaction of aqueous-phase aldol condensation between furfural and acetone.
Factors Influencing Teamwork in Health Care
Authors: Mijal Michał , Winter Małgorzata 
Published: November 2017

Abstract
The purpose of this paper is to analyse different views on interpersonal relations and team composition among managers and medical professionals with respect to the transition of professional roles in healthcare in Poland. To achieve that goal, a description based on a quantitative and qualitative questionnaire was conducted. Since the questionnaire covered various areas of health care, only its small fraction was used for the analysis. The main result is that most of the medical professionals and medical managers consider technology to be the single most important external factor influencing the team work efficiency and team composition in health care, and the managers consider skillset as the crucial factor determining whether a person would be a good team member. Based on the literature on professional roles in health care and their evolution in recent years, one can assume that constant development and lifelong learning would play a significant role in the healthcare systems reform. The findings are an important contribution to the discussion of the healthcare reform and its possible directions in future years as well a reference point for policy makers.
Promoting a Teacher Education Research-Oriented Curriculum for Initial Teacher Training in English as a Foreign Language
Authors: Ceia Carlos 
Published: November 2017

AbstractResearch-oriented programs related to pre-service teacher education are practically non-existent in many countries. Since in Portugal we now have a stable legal system for initial teacher training, how can we help these countries to respond to their teacher training needs and accomplish these same standards? How can we create an international program at MA level that could serve such an objective? What are the research priorities for teachers in primary and secondary education? I will claim for a new general research policy using small-scale research projects in foreign language teaching (FLT), which illustrated a turning point in advanced research in foreign languages teacher training. Presently, researchers no longer narrow their inquiries into linguistic questions or school and student-centered actions. Instead, they focus on a range of issues such as teacher-centered actions, beliefs and policies, and aspects of FLT such as literacy education, special educational needs or methods for teaching gifted students. Despite a lack of funding at all levels, many research projects in teacher education have been undertaken, and new areas have been explored, such as didactic transposition, literary and information literacies, intercultural learning, corpora in FLT, new information and communication technologies in FLT, interlingual inferencing, national standards for foreign language education, FLT for specific purposes, digital narratives in education, CLIL, assessment, and language learning behaviors. This small sample of the many areas covered proves that advanced research in teacher education can also be very useful to promote the growing interest in further internationalization in other sciences (beyond human and social areas) traditionally linked to politics, business and industry (computing, chemistry, biology, medicine, etc.), something that can only be attained by focusing on multilingualism, multi-literacy and lifelong learning.
Illustrating the Intercultural in Portuguese Secondary School Foreign Language (FL) Classrooms
Authors: Ulisses Carla , Hurst Nic 
Published: November 2017

Abstract
This article reports on a small-scale action research project developed in the context of the practicum of a Teacher Education Masters course at the Faculty of Letters, the University of Porto. The project was focussed on the importance of visual stimuli in the foreign language teaching classroom (English and Spanish), within the context of an intercultural approach. Different strategies, activities and materials were employed with the general aim of helping the learners to develop their critical cultural awareness. The learners played a central role, participating actively, by bringing into the classroom their own knowledge of the world. Simultaneously, the role of the teacher was not without importance in this action research project, presenting herself as an example of a cultural mediator.
Enhancing disciplinary literacies: languages of schooling and whole-school language projects in Spain
Authors: Pavón Víctor , Pérez America 
Published: November 2017

AbstractEuropean language policy focusing on the development of the languages of schooling is opening new paths to best fit the necessities of students, whether in bilingual or monolingual communities. Bilingual education is no longer an exclusive entity, but is increasingly becoming mainstreamed. In doing so, it can promote the consolidation of linguistic competence in all languages in the curriculum. Thus, in parallel with proposals whose aim is primarily to improve the use of disciplinary literacies in the foreign language used as the vehicle of instruction, there are programmes which seek to strengthen the foreign language, the mother tongue, and perhaps a second foreign language, through the use of subject-specific literacies (pluriliteracies) in all the languages. An example of this strategy can be found in some regions of Spain, with the decision to promote the academic language in distinct areas and in different languages through implementation of whole-school language projects. This article describes the forces and mechanisms underlying the proposal, its characteristics and practical application, and ultimately addresses the relevance of the scheme as a valuable tool to surpass the traditional objectives of bilingual education programmes and to enhance the attainment of pluriliteracies in the curriculum.
The relationship between soil properties, enzyme activity and land use
Authors: Błońska Ewa , Lasota Jarosław , Zwydak Maciej 
Published: November 2017

Abstract
The aim of this study was to assess the effects of different types of land use (forest, tillage and pasture) on soil properties, especially enzyme activity. Our investigation was carried out on 53 research plots with 11 plots in broadleaved forest stands, 12 plots in mixed broadleaved stands, 10 plots in mixed coniferous stands, 9 plots on tillage and 11 plots on pasture. The soil samples were collected from a depth of 0–15 cm after removing the organic horizon. Contents of organic carbon and nitrogen, pH and soil texture were investigated. Furthermore, dehydrogenase and urease activity were determined. Significant differences in the enzyme activity between forest and agricultural soils were observed, thus demonstrating that enzyme activity is influenced by the organic matter content of the soil. The highest enzyme activity was recorded in the forest soil within broadleaved stands, whilst the lowest activity was found in tillage soil, because tillage soil contained significantly less organic matter. High enzymatic activity of pasture soils is the combined result of vegetation type and the lack of plowing.
Evaluation of forestry companies with differing administrative and production costs
Authors: Wysocka-Fijorek Emilia 
Published: November 2017

AbstractThis paper contributes to the ongoing discussion on the improvement of private forest management in Poland. It examines characteristics of various types of forestry companies encompassing either completely private forests or a mixture of private and state-owned forests. Different possibilities for operating private and state-owned forestry companies were examined.The assessment of forestry companies was carried out for three categories based on forest inventory data and economic information. Each of the categories contained three different types of forestry companies classified as follows: I – companies managing private forests only, II – companies managing both private and state-owned forests (e.g. those managed by a state-run forest district), II – the same as in II but assuming minimal costs. The different types of forestry companies were then subjected to a more detailed analysis with respect to the following factors: A – only their own administrative costs, B – administrative costs and overheads assumed to be the same as in the State Forests, C – overheads assumed to be the same as in the State Forests but administrative costs are calculated as in A. For each of the scenarios, income, costs and revenues were calculated. The different types of forestry companies established above also allowed for an assessment of the used data and their collection.In conclusion, incomes of the forestry companies were generally low due to forest stands being managed by companies. Only in scenario A, which assumes very low management costs, did each of the company types gain revenues. This means that the main direction for the development of forestry companies should be to maintain low management costs.
An Albian demise of the carbonate platform in the Manín Unit (Western Carpathians, Slovakia)
Authors: Fekete Kamil , Soták Ján , Boorová Daniela , Lintnerová Otília , Michalík Jozef , Grabowski Jacek 
Published: November 2017

Abstract
The production of platform carbonates of the Manín Unit (Manín Straits, Central Western Carpathians) belonging to the Podhorie and Manín formations and formed by remains of rudists and benthic foraminifers (Urgonian-type carbonates), was previously assumed to terminate during the Aptian. First, we show that these deposits were primarily formed on the upper slope (Podhorie Formation) and in a fore-reef environment (Manín Formation). Second, biostratigraphic data indicate that the shallow-water production persisted up to the Albian, just as it did in another succession of the Manín Unit. The Podhorie Fm contains colomiellids (Colomiella recta, C. mexicana) and calcareous dinoflagellates (Calcisphaerula innominata) that indicate the Albian age. It also contains planktonic foraminifers (Ticinella roberti, Ticinella cf. primula, Ticinella cf. madecassiana, Ticinella cf. praeticinensis) of the Albian Ticinella primula Zone. The Podhorie Formation passes upwards into peri-reefal facies of the Manín Fm where we designate the Malý Manín Member on the basis of rudists shell fragments and redeposited orbitolinids. Microfacies associations share similarities with the Urgonian-type microfacies from Mediterranean Tethys and allow us to restrict the growth and the demise of the carbonate platform. δ13C and δ18O isotopes change over a broad range of both formations: δ13C is in the range +1.03 to +4.20 ‰ V-PDB and δ18O is in the range −0.14 to −5.55 ‰ V-PDB. Although a close correlation between δ13C and δ18O indicates diagenetic overprint, a long-term increase of δ13C can indicate a gradual increase in the aragonite production and/or increasing effects of oceanic water masses in the course of the Albian, prior to the final platform drowning. Carbonate platform evolution was connected with submarine slumps and debris flows leading to redeposition and accumulation of carbonate lithoclasts and bioclastic debris on the slope. Our study confirms that the growth of carbonate platforms in the Central Western Carpathians was stopped and the platform collapsed during the Albian, in contrast to the westernmost Tethys. A hardground formed during the Late Albian is overlain by Albian - Cenomanian marls of the Butkov Formation with calcisphaerulid limestones characterized by planktonic foraminifers of the Parathalmanninella appenninica Zone and calcareous dinoflagellates of the Innominata Acme Zone.
Geochemical characteristics and conditions of formation of the Chah-Bazargan peraluminous granitic patches, ShahrBabak, Iran
Authors: Fazlnia Abdolnaser 
Published: November 2017

Abstract
Xenoliths of garnet-biotite-kyanite schist from the Qori metamorphic complex (southern part of the Sanandaj-Sirjan zone, northeast Neyriz, Zagros orogen in Iran) in the 173.0±1.6 Ma Chah-Bazargan leuco-quartz diorite intrusion were studied. This intrusion caused these schist xenoliths to be metamorphosed to the pyroxene hornfels facies (approximately 4.5±1.0 kbar and 760±35 °C), converting them to diatexite migmatite as a result of partial melting of the xenoliths. These melts are granites in composition. Melt volumes of 20 to 30 vol. % were calculated for small patches of the peraluminous granites. It is possible that anatectic melting affected only the leucosome, such that melting was more than 20 to 30 vol. %. It is possible that a large amount of melt was not extracted due to balanced in situ crystallization, the adhesion force between melt and crystal (restite), and high viscosity of the leucosome. The Chah-Bazargan peraluminous granites are depleted in trace elements such as REEs, HFSE (Ti, Zr, Ta, Nb, Th, U, Hf, Y), Ba, Pb, and Sr. These elements are largely insensitive to source enrichment, but sensitive to the amounts of main and accessory minerals. These elements were hosted by minerals such as garnet, biotite, muscovite, K-feldspar, plagioclase, ilmenite, apatite, monazite, and zircon in the source (diatexitic migmatitic xenoliths).
Asteriacites and other trace fossils from the Po Formation (Visean–Serpukhovian), Ganmachidam Hill, Spiti Valley (Himalaya) and its paleoenvironmental significance
Authors: Singh Birendra P. , Bhargava Om N. , Mikuláš Radek , Prasad Subhay K. , Singla Garry , Kaur Ramanpreet 
Published: November 2017

Abstract
An assemblage of trace fossils comprising Asteriacites stelliformis, A. quinquefolius, Biformites insolitus, Helminthoidichnites? isp., Lingulichnus isp., Lockeia siliquaria, Palaeophycus tubularis, Planolites isp., Protovirgularia isp. A, Protovirgularia isp. B, Protovirgularia isp. C, Psammichnites isp., Rusophycus isp., and Treptichnus isp. from the Po Formation (Visean-Serpukhovian) exposed along the base of Ganmachidam Hill near the village of Chichong, Spiti Valley in the Himalaya, is described. Storm beds (tempestites) are highly bioturbated. Sedimentary structures such as hummocky cross-stratification (HCS), low-angle planar and trough cross beds, and shallow, slightly asymmetrical gutter casts are observed. The overall trace fossil assemblage indicates the presence of upper shoreface to lower shoreface Cruziana ichnofacies of an open shelf.
Ruled surfaces generated by elliptic cylindrical curves in the isotropic space
Authors: Aydin Muhittin Evren , Mihai Adela 
Published: November 2017

Abstract
In this paper we study the ruled surfaces generated by
elliptic cylindrical curves in the isotropic 3-space

𝕀
3

{\mathbb{I}^{3}}

.
We classify such surfaces in

𝕀
3

{\mathbb{I}^{3}}

with constant curvature and
satisfying an equation in terms of the components of the position vector
field and the Laplacian operator. Several examples are given and illustrated by figures.
Big Data for Biomedical Research and Personalised Medicine: an Epistemological and Ethical Cross-Analysis
Authors: Guillermin Mathieu , Magnin Thierry 
Published: November 2017

Abstract
Big data techniques, data-driven science and their technological applications raise many serious ethical questions, notably about privacy protection. In this paper, we highlight an entanglement between epistemology and ethics of big data. Discussing the mobilisation of big data in the fields of biomedical research and health care, we show how an overestimation of big data epistemic power – of their objectivity or rationality understood through the lens of neutrality – can become ethically threatening. Highlighting the irreducible non-neutrality at play in big data tools, we insist upon the ethical importance of a critical epistemological approach in which big data are understood as possibly valuable only when coupled with human intelligence and evaluative rationality.
Albert Camus’ Mediterranean: An Answer to “Murderous Identities”
Authors: Voisin Patrick 
Published: November 2017

Abstract
Identities were “murderous” in Algeria, to borrow an expression from Amin Maalouf. However, through this process, Algeria won its independence. Albert Camus, a son of France and a child of Algeria, caught between his two mothers’ identities, was torn apart and sometimes had to make choices; he was blamed for his Franco-French vision of Algeria and, above all, in the crucial hours, for preferring his biological mother to his cultural one. In other words, Camus had a poor record in Algeria. And yet, there is something like a tuning fork vibrating in unison at the sound of “Camus” and “Algeria”: it is Camus’ Mediterranean, with its timeless and universal present, which takes its sense and essence from the “Algerian Mediterraneanness”. It is a fact: Algeria allows us to understand Camus, but Camus also allows us to know Algeria. Questionable dark areas lie within either of them, but would not it be better if we imagined that Camus and Algeria could find together a world beyond the absurd and revolt, on a quest for universality that would not abolish identities which are still asserted but played down today?