bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: FIRST EXAMPLES OF MACROCYCLIC METAL CHELATE DERIVATIVES OF 5,12‐DIHYDRO‐1,2,5,8,9,12‐HEXAAZACYCLOTETRADECINE
Authors: DZIOMKO V. M. , FEDOSYUK L. G. , DUNAEVSKAYA K. A. 
Published: March 2016

AbstractDas aus dem Ketonitril (I) und Isopropylhydrazin (II) erhältliche Pyrazol (III) kuppelt mit der Diazoverbindung (IV) zur Azoverbindung (V).
ChemInform Abstract: NITRILOTRIACETOHYDROXAMIC ACID, DISSOCIATION CONSTANTS AND REACTIONS WITH COPPER(II) AND IRON(III)
Authors: KARLICEK R. 
Published: March 2016

AbstractMittels potentiometrischer und spektrophotometrischer Methoden werden die Dissoziationskonstanten des aus Nitrilotriessigsäuretrimethylester und Hydroxylamin in 83%iger Ausbeute erhaltenen Titelliganden und die Stabilitäts‐ und Gleichgewichtskonstanten der Cu(II)‐ und Fe(III)‐Komplexe (I)‐(VII) in Lösung bestimmt, die bei verschiedenen pH‐Werten gebildet werden.
ChemInform Abstract: COBALT(II), NICKEL(II), AND COPPER(II) NITRATE COMPLEXES WITH PYRAZINE N‐OXIDE
Authors: SPECA A. N. , KARAYANNIS N. M. , PYTLEWSKI L. L. , OWENS C. 
Published: March 2016

AbstractDie Umsetzung von Pyrazin‐N‐oxid mit 3d‐Metallnitraten liefert die Verbindungen (I) und (II).
ChemInform Abstract: SPECTROSCOPIC STUDY OF THE EQUILIBRIUM OF ADDUCT FORMATION BY ACETYLACETONATES OF OXOVANADIUM(IV) AND COPPER(II) WITH NITROGEN BASES
Authors: KWIATKOWSKI E. , TROJANOWSKI J. 
Published: March 2016

AbstractEs werden die Gleichgewichtskonstanten der 1:1‐Adduktbildung mit 30 N‐Basen wie z.B. Amine, Chinoline und Pyridine in Methylenchlorid bestimmt.
ChemInform Abstract: Stabile Cu(III) Complex Prepared.
Authors: MARGERUM D. W. 
Published: March 2016

AbstractNach Untersuchungen an der Purdue Univ., W. Lafayette, werden Cu(II)‐Ionen, die mit deprotonierten Amiden oder Peptiden komplexiert sind, unter Bildung von Cu(III)‐Komplexen oxidiert.
ChemInform Abstract: CATALYSIS BY METAL COMPLEXES. XXXIV. CATALYTIC ACTIVITY OF RHODIUM(I) COMPLEXES IN HYDROSILYLATION OF ALKENES
Authors: REJHON J. , HETFLEJS J. 
Published: March 2016

AbstractDie katalytische Aktivität einer Reihe von Rh(I)‐phosphin‐ und ‐phosphit‐Komplexen bei der Hydrosilylierung von Hexen‐(1) und von Styrol unter Bildung von l‐silyliertem Hexan bzw. 1‐ und 2‐silyliertem Phenyläthan wird untersucht.
ChemInform Abstract: SULFUR DIOXIDE INSERTIONS INTO PALLADIUM AND PLATINUM‐OXYGEN BONDS
Authors: ROS RENZO , CARTURAN GIOVANNI , GRAZIANI MAURO 
Published: March 2016

AbstractIn Methanol, Äthanol oder n‐Propanol suspendierte Pd(II)‐halogenide reagieren mit SO2 zu Zweikernkomplexen, die als Tetraphenylarsonium‐ und ‐phosphonium‐Salze (I) isoliert werden.
ChemInform Abstract: ENOL DERIVATIVES OF THE CHLOROPHYLL SERIES. PREPARATION OF 132,173‐CYCLOPHEOPHORBIDE ENOLS
Authors: FALK HEINZ , HOORNAERT GEORGES , ISENRING HANS‐PETER , ESCHENMOSER ALBERT 
Published: March 2016

AbstractDie Titelverbindungen (II), (IV) und (VI) werden als Modellsysteme für Untersuchungen des Einflusses der Enolisierung des E‐Ringes auf die Eigenschaften von Chlorophyllderivaten dargestellt.
ChemInform Abstract: New Chemical Route to Pure L‐Lysine.
Authors: SIFNIADES S. 
Published: March 2016

AbstractEine übersättigte Lösung des α‐Aminocaprolactam‐Nickel‐Komplexes (I) wird durch Umsetzung von DL‐Aminocaprolactam mit Nickel(II)‐chlorid in siedendem Äthanol in Gegenwart von Nickeläthylat hergestellt.
ChemInform Abstract: AMINO SUGARS. XXXIII. PREPARATION OF SOME METHYL 3‐ACETAMIDO‐3,6‐DIDEOXY‐β‐D‐HEXOPYRANOSIDES
Authors: CAPEK K. , STANEK J. JUN. , CAPKOVA J. , JARY J. 
Published: March 2016

AbstractDie Azidolyse des Galaktopyranosids (I) führt zum Glucosederivat (II), das als Diacetat isoliert wird, und zum Gulosederivat (IIIa), das mittels katalytischer Hydrierung in den Aminozucker (IIIb) übergeführt wird.
ChemInform Abstract: SYNTHESIS OF FLUORINATED BRANCHED‐CHAIN SUGARS
Authors: BISCHOFBERGER KARL , BRINK ABRAHAM J. , JORDAAN AMOR 
Published: March 2016

AbstractDie Reaktion der Glucofuranose (I) mit Fluoroxy‐trifluormethan in reinem CHQCI, gibt den Iminoester (IIa) und in Gegenwart von Spuren Wasser und Äthanol den Ketoester (IIb) und den Äthoxyester (III).
ChemInform Abstract: CONSTITUENTS OF EUPOMATIA SPECIES. IV. STRUCTURE AND SYNTHESIS OF EUPOLAURIDINE (EL BASE‐1) AND SOME OBSERVATIONS ON THE STRUCTURES OF EUPOLAURAMINE (EL BASE‐2) AND HYDROXYEUPOLAURAMINE (EL BASE‐3)
Authors: BOWDEN BRUCE F. , PICKER KELVIN , RITCHIE ERNEST , TAYLOR WALTER C. 
Published: March 2016

AbstractEupolauridin (EL Base‐1) besitzt die Struktur (Vc) und nicht, wie aufgrund spektroskopischer Untersuchungsergebnisse zunächst ebenfalls möglich erscheint, die isomere Struktur (IXc).
ChemInform Abstract: 5‐ALLYL‐9‐OXOBENZOMORPHANS. 2. CRYSTAL AND MOLECULAR STRUCTURE OF AN UNUSUAL PRODUCT OF DEQUATERNIZATION OF 5‐ALLYL‐9‐OXOBENZOMORPHAN METHOBROMIDE
Authors: AHMED FARID R. , SAUCIER MICHEL , MONKOVIC IVO 
Published: March 2016

AbstractDie der in der l. Mitt. beschriebenen Synthese von (VIa) analog verlaufende Synthese des Benzomorphanons (VIb) aus dem Tetralon (Ib) über die Stufen (IIb) bis (Vb) wird beschrieben.
ChemInform Abstract: REACTIONS OF CYTOSINE AND CYTIDINE WITH O‐SUBSTITUTED HYDROXYLAMINES
Authors: SCHALKE PETER M. , HALL C. DENNIS 
Published: March 2016

AbstractBei der Reaktion von Cytosin (Ia) oder Cytidin (Ib) mit einem Überschuß des Hydroxylamins (II) in Methanol‐Wasser bei einem pH‐Wert von 4‐5 erfolgt Substitution und Addition zu den Cytosinderivaten (III).
ChemInform Abstract: SYNTHESIS OF TRITIUM‐LABELED JUVENILE‐HORMONE‐EFFICIENT 10,11‐EPOXY‐6,7‐TRANS‐2,3‐TRANS‐FARNESYL 2‐PROPENYL ETHER WITH VERY HIGH SPECIFIC RADIOACTIVITY
Authors: SCHMIALEK P. 
Published: March 2016

AbstractAus Famesylbromid (I) und dem Na‐alkoholat (II) wird der Äther (III) dargestellt, der zu dem Epoxid (IV) oxidiert wird.
Relative Stereochemistry and Absolute Configuration of Farinosin, a Eudesmanolide From Encelia farinosa
Authors: Ortega Alfredo R. , Sánchez‐Castellanos Mariano , Pérez‐Hernández Nury , Robles‐Zepeda Ramón E. , Joseph‐Nathan Pedro , Quijano Leovigildo 
Published: March 2016

AbstractThe naturally occurring eudesmanolide farinosin (1) is now fully characterized for the first time despite its original isolation almost half a century ago. The early assumed relative stereochemistry and absolute configuration were confirmed by vibrational circular dichroism together with evaluation of the Hooft X‐ray parameters. The molecular conformation is very similar in the gas stage and in the solid state. Chirality 28:415–419, 2016. © 2016 Wiley Periodicals, Inc.
Nanostructure Architectures of Tungsten Carbide for Methanol Electrooxidation Catalyst
Authors: Jiang Yekun , Shi Meiqin , Tong Xue , Chu Youqun , Ma Chunan 
Published: March 2016

AbstractWe reported a novel protocol to efficiently synthesize tungsten carbide (WC) nanomaterials with pure crystal structure and certain specific morphology. The key step in this protocol is the preparation of the catalyst precursor W18O49 with surface oxygen vacancies. The existence of large quantities of oxygen vacancies gives plenty channels for diffusion and keeps the specific morphology of WC in the carbonization process. Efforts to build WC blocks with well‐defined geometrical shapes (e.g., rods, wires, spheres and flakes) have further expanded its possibility to be the support for methanol electrooxidation catalyst. The platinum supported on pure phase WC materials served as an effective CO tolerant electrocatalyst for methanol oxidation. Electrochemical experiments indicated that the improved catalytic activity was related to the special morphologies of WC supports. Its sea urchin like feature leads to substantial interfaces between WC and Pt by preparing more anchor points for Pt loading and also the barriers for the subsequent crystal growth, which enhances the synergistic effect between WC and Pt.
Cadmium–Aluminum Layered Double Hydroxide Microspheres for Photocatalytic CO2 Reduction
Authors: Saliba Daniel , Ezzeddine Alaa , Sougrat Rachid , Khashab Niveen M. , Hmadeh Mohamad , Al‐Ghoul Mazen 
Published: March 2016

AbstractWe report the synthesis of cadmium–aluminum layered double hydroxide (CdAl LDH) using the reaction‐diffusion framework. As the hydroxide anions diffuse into an agar gel matrix containing the mixture of aluminum and cadmium salts at a given ratio, they react to give the LDH. The LDH self‐assembles inside the pores of the gel matrix into a unique spherical‐porous shaped microstructure. The internal and external morphologies of the particles are studied by electron microscopy and tomography revealing interconnected channels and a high surface area. This material is shown to exhibit a promising performance in the photoreduction of carbon dioxide using solar light. Moreover, the palladium‐decorated version shows a significant improvement in its reduction potential at room temperature.
Dynamic joint model of capacitive charge pumps and on‐chip photovoltaic cells for CMOS micro‐energy harvesting
Authors: Ferro Esteban , López Paula , Brea Víctor Manuel , Cabello Diego 
Published: March 2016

SummaryOn‐chip energy harvesting by means of integrated photovoltaic cells in standard CMOS technology can be successfully used to recharge or power‐up integrated circuits with the use of charge pumps for voltage boosting. In this paper, a tool to facilitate the design of such structures is proposed consisting of an accurate model of the joint dynamics of the micro‐photovoltaic cell and a capacitive DC/DC converter in the slow‐switching limit regime. The model takes into account both the top and bottom parasitic capacitances of the flying capacitors. We assume a classical model for the photodiode whose photogenerated current is extracted from device‐level simulations. The joint model is verified by circuit‐level simulations achieving high accuracy and computation time savings of up to 1700×. The joint model shows that the voltage generated by an integrated photovoltaic cell connected to a capacitive DC/DC converter is not constant even under constant illumination. This phenomenon can only be reproduced through the joint model and failing to take it into account results in an error in the estimation of the time needed by the DC/DC converter to reach a given output voltage. We also demonstrate that the maximum output voltage reached by a DC/DC converter in the slow‐switching limit regime when a photovoltaic cell is used as energy transducer depends on the switching frequency. Finally, the applicability of the model is illustrated through the optimization of time response and charge efficiency for the Dickson, Fibonacci, and exponential topologies in the case of implantable devices. Copyright © 2016 John Wiley & Sons, Ltd.
Mowing strategies for controlling Cirsium arvense in a permanent pasture in New Zealand compared using a matrix model
Authors: Bourdôt Graeme W. , Basse Britta , Cripps Michael G. 
Published: March 2016

AbstractDefoliation has frequently been proposed as a means of controlling Cirsium arvense (L.) Scop. (Californian thistle, Canada thistle, creeping thistle, perennial thistle), an economically damaging pastoral weed in temperate regions of the world, but its optimization has remained obscure. We developed a matrix model for the population dynamics of C. arvense in sheep‐grazed pasture in New Zealand that accounts for the effects of aerial shoot defoliation on a population's photosynthetic opportunity and consequential overwintered root biomass, enabling mowing regimes varying in the seasonal timing and frequency of defoliation to be compared. The model showed that the long‐term population dynamics of the weed is influenced by both the timing and frequency of mowing; a single‐yearly mowing, regardless of time of year, resulted in stasis or population growth, while in contrast, 14 of 21 possible twice‐yearly monthly mowing regimes, mainly those with mowing in late spring, summer, and early autumn, resulted in population decline. Population decline was greatest (with population density halving each year) with twice‐yearly mowing either in late spring and late summer, early summer and late summer, or early summer and early autumn. Our results indicate that mowing can be effective in reducing populations of C. arvense in pasture in the long term if conducted twice each year when the initial mowing is conducted in mid spring followed by a subsequent mowing from mid summer to early autumn. These mowing regimes reduce the photosynthetic opportunity of the C. arvense population and hence its ability to form the overwintering creeping roots upon which population growth depends.
Internal concentration as a better predictor of metal toxicity than the fractional coverage of metals on biotic ligand: Comparison of 3 modeling approaches
Authors: Gao Yongfei , Feng Jianfeng , Zhu Lin 
Published: March 2016

Abstract

Modeling toxicity of metal mixtures poses unique challenges to the incorporation of bioavailability and metal speciation in metal exposures. Three models (models I, II, and III) were compared in the present study to predict and interpret the toxicity exerted by binary metal mixtures to zebrafish larvae, with the assumption of competition between metals based on the biotic ligand model and toxic potencies of individual metals. In addition, 3 models were developed by substituting binding constants (fMBL) for internal metal concentrations (CM,int) to directly delineate single-metal and mixture effects on mortality of zebrafish larvae. The results indicated that the 3 developed models appeared to be much better (p &lt; 0.01) than 3 previous models at assessing the toxicity of different metal mixtures and showed 10% to 20% predictive improvement for each metal combination, with the toxic equivalency factor–based model II showing the best performance at quantifying metal mixture toxicity. The 3 developed models generally provided a reasonable framework and descriptions of bioavailability and additive (or nearly additive) toxicity for a number of binary metal mixtures. Environ Toxicol Chem 2016;35:2721–2733. © 2016 SETAC
Glyphosate and aminomethylphosphonic acid chronic risk assessment for soil biota
Authors: von Mérey Georg , Manson Philip S. , Mehrsheikh Akbar , Sutton Peter , Levine Steven L. 
Published: March 2016

Abstract

Glyphosate is a broad-spectrum herbicide used widely in agriculture, horticulture, private gardens, and public infrastructure, where it is applied to areas such as roadsides, railway tracks, and parks to control the growth of weeds. The exposure risk from glyphosate and the primary soil metabolite aminomethylphosphonic acid (AMPA) on representative species of earthworms, springtails, and predatory soil mites and the effects on nitrogen-transformation processes by soil microorganisms were assessed under laboratory conditions based on internationally recognized guidelines. For earthworms, the reproductive no-observed-effect concentration (NOEC) was 472.8 mg glyphosate acid equivalent (a.e.)/kg dry soil, which was the highest concentration tested, and 198.1 mg/kg dry soil for AMPA. For predatory mites, the reproductive NOEC was 472.8 mg a.e./kg dry soil for glyphosate and 320 mg/kg dry soil for AMPA, the highest concentrations tested. For springtails, the reproductive NOEC was 472.8 mg a.e./kg dry soil for glyphosate and 315 mg/kg dry soil for AMPA, the highest concentrations tested. Soil nitrogen-transformation processes were unaffected by glyphosate and AMPA at 33.1 mg a.e./kg soil and 160 mg/kg soil, respectively. Comparison of these endpoints with worst-case soil concentrations expected for glyphosate (6.62 mg a.e./kg dry soil) and AMPA (6.18 mg/kg dry soil) for annual applications at the highest annual rate of 4.32 kg a.e./ha indicate very low likelihood of adverse effects on soil biota. Environ Toxicol Chem 2016;35:2742–2752. © 2016 The Authors. Environmental Toxicology and Chemistry Published by Wiley Periodicals, Inc. on behalf of SETAC.
An Investigation of the Use and Predictive Validity of Scores From the GRE® revised General Test in a Singaporean University
Authors: Liu Ou Lydia , Klieger David M. , Bochenek Jennifer L. , Holtzman Steven L. , Xu Jun 
Published: March 2016

AbstractInternational institutions have been increasingly using the GRE® revised General Test to admit students to graduate programs. However, little is known about how scores from the GRE revised General Test are used in the admission process outside of the United States and their validity in predicting graduate students' performance (e.g., their graduate school grade point averages [GGPAs]). As the GRE revised General Test was launched in August 2011, there is a compelling need to investigate its predictive validity, particularly in an international context. A large percentage of examinees who take the GRE revised General Test from outside of the United States are citizens of Asian countries. Consequently, we examined how scores from the GRE revised General Test predict a range of graduate student performance outcomes at a Singaporean institution that represents the highest caliber of academic excellence in Asian countries. We also interviewed key members of the admissions committees to understand how the GRE revised General Test and its individual sections are used in the admission process. Our analyses revealed that scores from the GRE revised General Test predicted GGPA and program standing. In particular, these scores showed incremental value beyond undergraduate GPA (UGPA) for predicting GGPA. Furthermore, among enrolled students, those who submitted scores from the GRE revised General Test in application had significantly higher GGPAs than those who did not. These findings largely apply to both doctoral and master's students.
An event simulation approach to the assessment of flood level frequencies: risk maps for the Warsaw reach of the River Vistula
Authors: Romanowicz R. J. , Kiczko A. 
Published: March 2016

AbstractFlood risk assessment is customarily performed using a design flood. Observed past flows are used to derive a flood frequency curve which forms the basis for a construction of a design flood. The simulation of a distributed model with the 1‐in‐T year design flood as an input gives information on the possible inundation areas, which are used to derive flood risk maps. The procedure is usually performed in a deterministic fashion, and its extension to take into account the design flood‐and flow routing model uncertainties is computer time consuming. In this study we propose a different approach to flood risk assessment which consists of the direct simulation of a distributed flow routing model for an observed series of annual maximum flows and the derivation of maps of probability of inundation of the desired return period directly from the obtained simulations of water levels at the model cross sections through an application of the Flood Level Frequency Analysis. The hydraulic model and water level quantile uncertainties are jointly taken into account in the flood risk uncertainty evaluation using the Generalized Likelihood Uncertainty Estimation (GLUE) approach. An additional advantage of the proposed approach lies in smaller uncertainty of inundation predictions for long return periods compared to the standard approach. The approach is illustrated using a design flood level and a steady‐state solution of a hydraulic model to derive maps of inundation probabilities. Copyright © 2016 John Wiley & Sons, Ltd.
TET2 regulates LncRNA‐ANRIL expression and inhibits the growth of human gastric cancer cells
Authors: Deng Wei , Wang Jin , Zhang Jun , Cai Jun , Bai Zhigang , Zhang Zhongtao 
Published: March 2016

AbstractTen‐eleven translocation (TET) family enzymes convert 5‐methylcytosine to 5‐hydroxymethylcytosine in DNA. However, the role of TET enzymes in human gastric cancer remains unknown. Here, we show that TET2 mRNA and protein levels are downregulated in human gastric cancer tissues when compared with normal gastric mucosa. Low expression of TET2 predicts poor overall and disease‐free survival. Furthermore, we demonstrate that TET2 inhibits the proliferation and colony formation of human gastric cancer cells by using loss‐of‐function and gain‐of‐function strategies. Overexpression of TET2 induces apoptosis in human gastric cancer cells. The mechanism study shows that TET2 binds to the promoter region of the oncogenic long noncoding RNA (lncRNA‐ANRIL) and regulates the expression of ANRIL and its downstream genes (INK4a, INK4b, and ARF). Finally, we demonstrate that ANRIL knockdown blocks the effects of TET2 on gastric cancer cell proliferation and colony formation. © 2016 IUBMB Life 68(5):355–364, 2016
Induction Chemotherapy for p16 Positive Oropharyngeal Squamous Cell Carcinoma
Authors: Saito Yuki , Ando Mizuo , Omura Go , Yasuhara Kazuo , Yoshida Masafumi , Takahashi Wataru , Yamasoba Tatsuya 
Published: March 2016

Objectives/HypothesisWe aimed to determine the effectiveness of induction chemotherapy for treating p16‐positive oropharyngeal cancer in our department.Study DesignThis was a retrospective case series to assess treatment effectiveness.MethodsWe administered induction chemotherapy to patients with stage III to IV oropharyngeal p16‐positive squamous cell carcinoma between 2008 and 2013. Induction chemotherapy was administered using combinations of docetaxel, cisplatin, and 5‐fluorouracil. We measured the survival rates using the Kaplan‐Meier method and log‐rank test.ResultsWe reviewed 23 patients (18 men and 5 women; age, 42–79 years). Induction chemotherapy resulted in partial or complete remission (20 patients) and in stable (2 patients) or progressive (1 patient) disease. In partial or complete remission, subsequent radiotherapy was performed in 16 patients, chemoradiotherapy in two, and transoral resection in two. In stable or progressive disease, subsequent open surgery was performed. Overall, one patient died of cervical lymph node metastasis, one died of kidney cancer, and one died of myocardial infarction. Event‐free, distant‐metastasis–free survival was present for 20 patients. The 3‐year disease‐specific survival was 95%; the overall survival was 87%. Two patients required gastrostomies during chemoradiotherapy and three required tracheotomies, but these were closed in all patients.ConclusionThe therapeutic response to induction chemotherapy for p16‐positive oropharyngeal cancer was good. Partial or complete remission was achieved in almost 90% patients, and control of local and distant metastases was possible when it was followed by radiotherapy alone or with transoral resection of the primary tumor. A multicenter study is required to confirm these findings.Level of Evidence4.
It's Time for the Genetic Counseling Profession to Embrace Social Media
Authors: Gallagher Lauren , McCuaig Jeanna , Benoit Lacey , Davies Christine 
Published: March 2016

AbstractSocial Media is a powerful and emerging method of communication that is becoming increasingly popular in genetic counseling and other health care communities. Despite its multiple benefits, the Social Media revolution has been met with some resistance in the healthcare setting. Herein, we will describe the potential benefits of Social Media for the genetic counseling profession specifically and explore ways in which any risks can be mitigated and barriers overcome to ensure responsible Social Media use by the profession.