bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multilevel thoracic myelopathy: full-endoscopic solution. Illustrative case
Authors: Sura Sukumar , Dave Harshit , Reddy Mallepally Abhinandan , Reddy Rajendra , Tulasi Ram H. C. V , Ravikanti Padma , Kumar Pagidimarry Naresh 
Published: October 2024

BACKGROUND
Thoracic myelopathy is relatively uncommon but, when present, causes significant disability. Early surgical intervention is often recommended for patients with myelopathy with compression at multiple levels. Surgical approaches and techniques for thoracic myelopathy have evolved from traditional open spine surgery to less invasive full-endoscopic spine surgery.

OBSERVATIONS
This article reports an unusual presentation of a 31-year-old male with thoracic myelopathy due to thoracic disc herniation (TDH) at the T8–9 level and ossification of the ligamentum flavum at the T10–11 level that was managed using full-endoscopic spine surgery techniques in a single sitting. The presence of coexisting spinal disorders, that is, TDH and ossification of the posterior longitudinal ligament at noncontiguous spinal levels, makes surgical decision-making more complicated.

LESSONS
Uniportal full-endoscopic spine surgery is a safe and effective surgical technique even for thoracic myelopathy. It is less invasive with minimal tissue and bone damage, better access to and visualization of the pathology, and minimal cord handling and is performed through small windows without destabilizing the spine, thus avoiding fusion. Anterior thoracic pathologies are better addressed through the transforaminal approach, whereas the interlaminar approach is preferred for posterior pathologies. Both of these approaches are complementary to each other with their own indications and advantages.
https://thejns.org/doi/10.3171/CASE24413
Ожидаемая продолжительность здоровой жизни как компонент развития человеческого капитала
Authors: Кучмаева О.В. , Калмыкова Н.М. , Колотуша А.В. 
Published: October 2024

Оценка качества жизни в регионе невозможна без учета общественного здоровья. В этих целях часто используется Индекс человеческого развития (ИЧР), который оценивает человеческий потенциал. Однако индекс ожидаемой продолжительности жизни при рождении (ОПЖ), входящий в состав ИЧР как индикатор долголетия, не учитывает состояния здоровья населения. Исследование доказывает возможность использования показателя ожидаемой продолжительности здоровой жизни (ОПЗЖ) в интегральной оценке качества жизни. Сравнительная оценка ситуации в регионах России в 2019–2020 гг. на основе предложенной методики, включая результаты дисперсионного анализа, показывает, что использование ОПЗЖ в качестве показателя здоровья более точно объясняет различия между регионами России по ИЧР. Различия в качестве жизни жителей регионов в основном определяются такими детерминантами здоровья, как доступность медицинских услуг, экологическая ситуация и условия труда. Доступность образования практически не влияет на различия в ИЧР между регионами. Полученные результаты подчеркивают необходимость сравнительного анализа Индекса ОПЗЖ и его использования в качестве показателя здоровья. Данные выборочных обследований в России позволяют уточнить методику ОПЗЖ и использовать характеристики ограничений по здоровью, что улучшит оценку состояния здоровья населения.
Assessment of quality of life in the region is impossible without taking into account public health. For this, Human Development Index (HDI) is often used, which evaluates human potential. However, index of life expectancy (LE), which is part of the HDI as an indicator of the longevity, does not take into account the health status of the population. The study proves the possibility of using the “indicator of healthy life expectancy” (HLE) in the integral assessment of life quality. Comparative assessment of the situation in the Russia’s regions in 2019–2020 based on the proposed methodology shows that the use of HLE as an indicator of health more accurately explains the differences between Russia’s regions in terms of HDI. Differences in the quality of life of residents of regions are mainly explained by determinants of health, such as the availability of medical services. The availability of education practically does not affect the differences in HDI between the regions. These results emphasize the need for a comparative analysis of HLE Index and its use as an indicator of health. The data of sample surveys in Russia allows us to clarify the methodology of HLE and use the characteristics of health restrictions, which will improve assessment of the population’s health status.
Формирование отечественных сетей добавленной стоимости
Authors: Полтерович В.М. 
Published: October 2024

В статье вводится понятие СДС-консорциума, отличающегося двумя специфическими чертами. Во-первых, такой консорциум включает группу предприятий, осуществляющих последовательные стадии производства одного или нескольких продуктов. Во-вторых, в задачи СДС-консорциума входит разработка и реализация проектов создания и/или внедрения новых технологий, предназначенных для использования в его сети, в том числе предприятиями из разных отраслей народного хозяйства. Поэтому в его составе должны быть организации, способные выполнять такие задачи, возможно, с привлечением временных участников — научно-исследовательских и проектных институтов. Члены консорциума сохраняют свою самостоятельность. Согласование их деятельности осуществляется координационным советом, образованным из их представителей. На реальных примерах показано, что консорциумы подобного типа способны обеспечить формирование и функционирование отечественных сетей добавленной стоимости (СДС). Такие сети необходимы для технологического развития страны, находящейся под жестким санкционным давлением. Создание СДС-консорциумов могло бы стать важным элементом индикативного плана, а государственная поддержка способствовала бы становлению СДС-консорциума как коллаборативного института.
The concept of the VAN-consortium is introduced. It is a consortium, distinguished by two specific features. Firstly, it includes a group of enterprises that carry out successive stages of production of one or more products. Secondly, the tasks of a VAN-consortium include the development and implementation of projects for the creation and/or implementation of new technologies intended for use in its network, including by enterprises from various sectors of the national economy. Therefore, it should incorporate organizations capable of performing such tasks, possibly involving temporary participants – research and project institutes. Members of the consortium retain their independence. Coordination of their activities is carried out by a coordination council consisting of their representatives. Real examples show that consortia of this type are capable of ensuring the formation and functioning of domestic value-added networks (VANs). Such networks are necessary for the technological development of a country under severe sanctions pressure. The creation of VAN-consortia could become an important element of indicative plans, and government support would contribute to the development of the VAN-consortium as a collaborative institution.
Laboratory work in physics "The study of uniformly accelerated motion without initial velocity" using a robotic kit LEGO MINDSTORMS EDUCATION EV3
Authors: Blinov D. M. 
Published: October 2024

The article presents an example of using a robotic kit at physics and informatics lessons — a laboratory work "The study of uniformly accelerated motion without initial velocity" using the LEGO MINDSTORMS EDUCATION EV3 kit. This work is intended for students in 9–10th grades when studying uniformly accelerated motion in a physics course. During the laboratory work, it is necessary to: assemble an experimental setup and create a program for the EV3 control module, which should record the time of movement of a ball along an inclined chute with output to the EV3 module screen; enter the obtained measurement results into a calculation table compiled in an electronic spreadsheet, into which formulas for automatic calculation of acceleration and instantaneous velocity of the ball are preliminarily entered. The laboratory work can be carried out both in a physics and an informatics lessons, and in an optional lesson, you can also conduct an integrated physics and informatics lesson. The use of robotic modeling introduces students to the modern process of conducting physical research (experiments), helps to increase students' interest in experimental work, develop their skills in using robots in research and motivation for engineering and technical creativity.
Analisis Komitmen Kerja Pada Rumah Sakit Paru Jember Tahun 2021-2022
Authors: Muachiroh Muachiroh , Sanosra Abadi , Herlambang Toni 
Published: October 2024

Penelitian ini dilakukan dilingkungan Rumah Sakit Paru Jember. Jumlah populasi seluruh pegawai “Rumah Sakit Paru Jember” yang diambil sebanyak 325 orang pegawai, maka populasi dalam penelitian ini bertindak pula menjadi sampel, atau penelitian ini dapat dikatakan menggunakan metode sampel jenuh. Analisis data dan permodelan persamaan struktural dengan menggunakan software Smart PLS 4.0. Penelitian ini termasuk explanatory research. Tujuan penelitian untuk mengetahui apakah lingkungan kerja berpengaruh positif dan signifikan terhadap komitmen kerja, untuk mengetahui apakah kompensasi berpengaruh positif dan signifikan terhadap komitmen kerja, untuk mengetahui apakah lingkungan kerja berpengaruh positif dan signifikan terhadap kepuasan kerja, untuk mengetahui apakah kompensasi berpengaruh positif dan signifikan terhadap kepuasan kerja, untuk mengetahui apakah kepuasan kerja berpengaruh positif dan signifikan terhadap komitmen kerja, untuk mengetahui apakah lingkungan kerja berpengaruh positif dan signifikan terhadap komitmen kerja melalui kepuasan kerja, dan untuk mengetahui apakah kompensasi berpengaruh positif dan signifikan terhadap komitmen kerja pada pegawai rumah sakit paru jember melalui kerja kepuasan. Hasil uji menyatakan bahwa tidak ada pengaruh signifikan antara lingkungan kerja terhadap kepuasan kerja, hasil uji ada pengaruh signifikan antara kompensasi terhadap kepuasan kerja, hasil uji ada pengaruh signifikan antara lingkungan kerja terhadap komitmen kerja, uji tidak berpengaruh signifikan antara kompensasi terhadap komitmen kerja, hasil uji terdapat pengaruh signifikan antara kepuasan kerja terhadap komitmen kerja, hasil uji tidak terdapat pengaruh lingkungan kerja terhadap komitmen kerja melalui kepuasan kerja, dan hasil uji terdapat pengaruh kompensasi terhadap komitmen kerja melalui kepuasan kerja pegawai Rumah Sakit Paru Jember.
Calprotectin as a marker of disease activity in spondyloarthritis
Authors: Florica Ioana Tereza , Harney Sinead 
Published: October 2024

Introduction: Spondyloarthritis is a group of arthritic diseases that classically manifest as inflammation of the sacroiliac and limb joints, as well as the axial skeleton. Microscopic bowel inflammation is identifiable in over 50% of these patients. Calprotectin measured in the serum and stool is an emerging surrogate marker of disease activity and/or bowel inflammation in spondyloarthritis.
Objective: This article aims to review published literature to determine the accuracy of serum and faecal calprotectin levels for use in monitoring bowel inflammation and spondyloarthritis disease activity.
Methods: Boolean operator strategy was used to search two databases (Embase and PubMed) and 52 relevant articles were identified. Duplicate results were eliminated, inclusion and exclusion criteria were applied.
Results: Ten studies met the inclusion criteria and were summarized and analyzed. The EBL Validity questionnaire was applied to determine study quality. All research articles found calprotectin to be elevated in spondyloarthritis patients when compared to controls. Faecal calprotectin was superior in detecting disease activity and correlated with disease activity questionnaires, radiology and endoscopy results. Only one study assessed the effect of treatment on calprotectin and its correlation to bowel inflammation.
Conclusion: Faecal calprotectin shows promise as a surrogate marker for disease activity and bowel inflammation in spondyloarthritis. Future studies should focus on the effect of treatment on faecal calprotectin and whether some treatments are better at preventing the progression of bowel inflammation in addition to treating spondyloarthritis. Supplementary investigations are needed to identify whether faecal calprotectin is useful as a marker of disease activity in response to treatment.
The need for health literacy in the 21st century
Authors: Pérez Gutiérrez Alejandro , Pino Juste Margarita 
Published: October 2024

Health literacy is the ability of individuals to understand, evaluate and use health information effectively in their daily lives and should not be reduced to the simple ability to read or write about health-related topics. With appropriate health literacy, citizens will gain greater autonomy in their self-care, improve their quality of life and make better use of health services, thereby reducing health service overload, inequalities and costs. To increase health literacy, it is necessary to identify the specific health needs of today's society and to implement educational programmes that include content and pedagogical methods that address these needs. Addressing these needs requires a diagnostic analysis embedded in each culture and continuous re-evaluation of the scope and effectiveness of the programmes implemented from an interdisciplinary perspective. Currently, most community and school-based programmes are based on disease prevention and maintaining good sexual and environmental health. Since the pandemic, there has also been an increase in programmes to achieve and maintain good mental health, combined with the use of various applications to prevent anxiety and depression. However, there is still a large gap in the evaluation of the impact and effectiveness of these programmes. In general, most of these programmes need to be adapted to the digital age and have a comprehensive and holistic design and purpose. In conclusion, we believe that health literacy is essential in the 21st century and that it must be based on the promotion of healthy habits and behaviours as well as an understanding of one's own health.
Synthesis of metal nanoparticles on graphene oxide and antibacterial properties
Authors: Tene Talia , Bellucci Stefano , Pachacama Joseth , Cuenca-Lozano María F. , Tubon-Usca Gabriela , Guevara Marco , La Pietra Matteo , Cruz Salazar Yolenny , Scarcello Andrea , Arias Polanco Melvin , Gahramanli Lala Rasim , Vacacela Gomez Cristian , Caputi Lorenzo S. 
Published: October 2024

Pathogen-induced infections and the rise of antibiotic-resistant bacteria, such as Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), pose significant global health challenges, emphasizing the need for new antimicrobial strategies. In this study, we synthesized graphene oxide (GO)-based composites functionalized with silver nanoparticles (AgNPs) and copper nanoparticles (CuNPs) as potential alternatives to traditional antibiotics. The objective is to assess the antibacterial properties of these composites and explore their efficacy against E. coli and S. aureus, two common bacterial pathogens. The composites are prepared using eco-friendly and conventional methods to ensure effective nanoparticle attachment to the GO surface. Structural and morphological characteristics are confirmed through SEM, AFM, EDS, XRD, UV-vis, FTIR, and Raman spectroscopy. The antibacterial efficacy of the composites is tested through disk diffusion assays, colony-forming unit (CFU) counts, and turbidimetry analysis, with an emphasis on understanding the effects of different nanoparticle concentrations. The results demonstrated a dose-dependent antibacterial effect, with GO/AgNP-1 showing superior antibacterial activity over GO/AgNP-2, particularly at lower concentrations (32.0 μg/mL and 62.5 μg/mL). The GO/CuNP composite also exhibited significant antibacterial properties, with optimal performance at 62.5 μg/mL for both bacterial strains. Turbidimetry analysis confirmed the inhibition of bacterial growth, especially at moderate concentrations, although slight nanoparticle aggregation at higher doses reduced efficacy. Lastly, both GO/AgNP and GO/CuNP composites demonstrated significant antibacterial potential. The results emphasize the need to fine-tune nanoparticle concentration and refine synthesis techniques to improve their efficacy, positioning these composites as strong contenders for antimicrobial use.
Including educational status may improve cardiovascular risk calculations such as SCORE2
Authors: Dienhart Christiane , Gostner Isabella , Frey Vanessa , Aigner Elmar , Iglseder Bernhard , Langthaler Patrick , Paulweber Bernhard , Trinka Eugen , Wernly Bernhard 
Published: October 2024

BackgroundThe association between education and atherosclerotic cardiovascular disease (ASCVD) has been well described for decades. Nevertheless, most cardiovascular risk models, including SCORE2, still do not take educational status into account even if this factor is easily assessed and costs nothing to acquire. Using carotid plaques as a proxy for ASCVD, we analysed educational status as associated with carotid plaque development, to determine if the relationship remains, how it relates to traditional risk factors and, how it impacts the European cardiovascular risk model, SCORE2. Our study also provides further data on plaque development in a well-characterised population nearly equally weighted by gender.Methods9,083 subjects (51% female, 49% male) from the Paracelsus 10,000 cohort, underwent a carotid doppler duplex as part of thorough screening for subclinical ASCVD. Well over 90% of carotid doppler duplex examinations were performed by the same experienced clinician. Subjects were then classified by educational status using the Generalized International Standard Classification of Education. Plaque absence or presence was dichotomised and variables analysed using regression modelling to examine educational status relative to cardiovascular risk factors and with respect to the SCORE2 model.ResultsUsing medium educational status as a reference, subjects in our cohort with low educational status had higher odds, while subjects with high educational status had lower odds for carotid plaques compared to subjects with medium education (aOR 1.76 95%CI 1.50–2.06; and 0.0.63 95%CI 0.57–0.70, respectively). Even after adjusting for common risk factors including metabolic syndrome and SCORE2, the relationship was maintained. Furthermore, when comparing the potential predictive power of SCORE2 alone and plus educational status using the Akaike information criterion, we showed a ‘better fit’ when educational status was added.ConclusionsMeasuring educational status is cost-free and easy for clinicians to obtain. We believe cardiovascular risk prediction models such as SCORE2 may more accurately reflect individual risk if educational status is also taken into account. Additionally, we believe clinicians need to understand and appropriately address educational status as a risk factor, to better quantify individual risk and take appropriate measures to reduce risk so that the association may finally be broken.
The relationship between oxidative balance score and circadian syndrome: evidence from the NHANES 2005-2018
Authors: Xie Lin , Li Juan , Xu Mingzhi , Lei Yahan , Chen Xushan , Xie Jiajia 
Published: October 2024

BackgroundThe oxidative balance score (OBS) is a composite indicator that evaluates the balance between pro-oxidants and antioxidants in one’s diet and lifestyle. However, the relationship between OBS and circadian syndrome (CircS) has remained unexplored. This investigation aimed to determine a correlation between OBS and CircS.MethodsThis population-based study examined 7,202 participants from the 2005 to 2018 National Health and Nutrition Examination Survey (NHANES), 1,433 of whom had CircS. We utilized weighted multivariate logistic regression, trend tests, subgroup analysis, and interaction tests to evaluate the correlation between OBS (total OBS, dietary OBS, and lifestyle OBS) and CircS. Restricted cubic splines (RCS) models and threshold effect analysis were used to explore nonlinear relationships.ResultsMultivariate logistic regression analysis indicated that the protective factor for CircS was a high OBS level (total OBS: Odds ratio (OR) = 0.95, 95% Confidence interval (CI): 0.93-0.97; dietary OBS: OR = 0.98, 95% CI: 0.96-1.00; lifestyle OBS: OR = 0.65, 95% CI: 0.61-0.69). Compared to the quartile 1 group, OBS (total OBS, dietary OBS, and lifestyle OBS) was negatively and statistically significantly associated with the risk of developing Circs in the quartile 4 group (total OBS: OR = 0.47, 95% CI: 0.32-0.70; dietary OBS: OR = 0.69, 95% CI: 0.48-0.99; lifestyle OBS: OR = 0.07, 95% CI: 0.04-0.11). According to subgroup analysis and interaction tests, there was an interaction effect between the association of lifestyle OBS and CircS in terms of education level (p for interaction = 0.01). Furthermore, we observed a nonlinear negative relationship between lifestyle OBS and CircS prevalence, with inflection points at 6 (p for nonlinearity = 0.002).ConclusionThe results showed a substantial negative connection between OBS and CircS. Encouraging foods filled with antioxidants and antioxidant-rich lifestyles may reduce the risk of CircS.
Effect of gradual pollen presentation on pollination efficiency and reproduction of Vaccinium corymbosum Berkeley in two habitats
Authors: Sun Ke Xin , Zhang Yan Jia , Zhou Chun Zhi , Yang Shan Lin , Jiang Hui Xin , Cui Rong Rong 
Published: October 2024

IntroductionGradual pollen presentation is a reproductive strategy for plants to improve the efficiency and accuracy of pollen export and acceptance as well as to promote outcrossing. Vaccinium corymbosum Berkeley has a typical mechanism of gradual pollen presentation.MethodsIn this study, we used indoor and outdoor observations to investigate the floral characteristics, pollination characteristics and breeding system of this species in open ground and greenhouse.ResultsThe results showed that the single white, inverted bell-shaped flower of V. corymbosum was able to effectively avoid the negative effects of rainfall, nectar dilution and pollen removal by wind, and improved pollen viability and the duration of stigma receptivity. The setting rate of ‘Northland’ is higher than open ground by artificial pollination in greenhouse, therefore, greenhouses are more suitable for ‘Northland’ reproduction. The gradual pollen presentation prolongs dispersal time, promotes pollinator participation in the pollination process, increases staminate fitness, and provides for nectar feeding by pollinators as well as pollen export. Bombus spp. and A. m. ligustica were effective pollinators in the open ground and greenhouse, and the pollination efficiency of Bombus spp. was higher than that of A. m. ligustica, and greenhouse pollination is more efficient than open ground. The coincidence of the peak period of pollinator visits with the period of highest pollen viability and optimal pollination of stigmas, as well as the high nectar production, could maximize the frequency of pollinator visits and increase the chances of successful pollination as well as the pollination efficiency.DiscussionTherefore, it is important to study the floral characteristics of V. corymbosum Berkeley and the mechanism of gradual pollen presentation in order to improve the pollination efficiency and promote the success of outcrossing, which can provide a theoretical basis for the breeding of V. corymbosum.