bluuebunny/crossref_metadata_2025_split huggingface dataset:
A nurse-led multidisciplinary team approach in urology-oncology: Addressing the new cancer strategy
Authors: McGlynn Brian , Johnston Maximilian , Green James 
Published: March 2017

Objectives: The urology-oncology service in NHS Ayrshire and Arran (AA) is nurse-led, with a multidisciplinary team (MDT) process at its core. Here, we assess the efficacy of this nurse-led service against similar services and consider it in the context of the new NHS cancer strategy. Materials and methods: Audit data regarding the management of patients with urological malignancies published by the West of Scotland Cancer Network (WoSCAN) were compared against pre-determined quality performance indicators. These data were used to assess the efficacy of the NHS AA service against the other WoSCAN centres. Results: All parameters analysed were comparable, except for the following performance indicators for which the NHS AA data appeared to show significant improvement compared with the other WoSCAN centres: the number of patients with bladder cancer with recorded TNM clinical staging ( p = 0.012); the proportion of patients with prostate cancer who underwent transrectal ultrasound-guided prostate biopsy for histological diagnosis where a minimum of 10 cores are received by pathology ( p = 0.043); and the number of patients with metastatic prostate cancer who underwent immediate hormone therapy ( p = 0.031). Conclusion: Our analysis demonstrates that the NHS AA urology-oncology nurse-led MDT-based service is a highly efficient and well-functioning structure.
Increased risk for posterior circulation ischaemia in patients with vertebral artery hypoplasia: A systematic review and meta-analysis
Authors: Katsanos Aristeidis H , Giannopoulos Sotirios 
Published: March 2017

Introduction Although several study protocols reported that vertebral artery hypoplasia can predispose to posterior circulation ischaemia, the role of vertebral artery hypoplasia in the risk of posterior circulation ischaemia still remains controversial. The aim of the present meta-analysis was to investigate the association of vertebral artery hypoplasia and posterior circulation ischaemia. Patients and methods We performed a systematic review and random effects meta-analysis of all eligible observational study protocols reporting prevalence rates of vertebral artery hypoplasia in patients with anterior circulation ischaemia and posterior circulation ischaemia. Results We identified eight study protocols including a total of 3875 acute ischemic stroke patients (mean age: 64.2 years, 61.3% males) and reporting a pooled prevalence of vertebral artery hypoplasia 18.6% (95%CI: 10.8–30.0%). In the overall analysis, a significantly higher probability of vertebral artery hypoplasia presence was found in posterior circulation ischaemia patients compared to patients with anterior circulation ischaemia (risk ratio = 2.12, 95%CI: 1.60–2.82, p < 0.001). In the subsequent sensitivity analysis, vertebral artery hypoplasia was again found to be significantly more prevalent in patients with posterior circulation ischaemia compared to anterior circulation ischaemia (risk ratio = 1.81, 95%CI: 1.58–2.06, p < 0.001), with no evidence of heterogeneity (I2 = 0%, p for Cochran Q = 0.55) between included studies. Discussion The present report is a meta-analysis of retrospective observational study protocols, with all the inherent limitations of included studies. The heterogeneity on the reported rates of vertebral artery hypoplasia could be attributed to differences in population age, sex, race, imaging protocols and vertebral artery hypoplasia definition between included studies. Conclusion Our meta-analysis provides further evidence for a possible causal relationship between vertebral artery hypoplasia and cryptogenic posterior circulation ischaemia, an association which undoubtedly deserves further investigation in future prospective study protocols.
Use of ‘tidal volume challenge’ to improve the reliability of pulse pressure variation
Authors: Myatra Sheila Nainan , Monnet Xavier , Teboul Jean-Louis 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Anemia and blood transfusion in the critically ill patient with cardiovascular disease
Authors: Docherty Annemarie B. , Walsh Timothy S. 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
High-flow nasal cannula support therapy: new insights and improving performance
Authors: Hernández Gonzalo , Roca Oriol , Colinas Laura 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Neuroanatomy of sepsis-associated encephalopathy
Authors: Heming Nicholas , Mazeraud Aurelien , Verdonk Franck , Bozza Fernando A. , Chrétien Fabrice , Sharshar Tarek 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.Originally published in the Annual Update in Intensive Care and Emergency Medicine 2017. The number of authors differs in the two versions due to constraints regarding the number of authors in the Annual Update in Intensive Care and Emergency Medicine. In the Annual Update version of the review, the three senior authors appear in the acknowledgement section. In the Critical Care version, these three senior authors appear as full authors of the manuscript. All authors helped draft and revise the manuscript for critical intellectual content.
Medicating patients during extracorporeal membrane oxygenation: the evidence is building
Authors: Dzierba Amy L. , Abrams Darryl , Brodie Daniel 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Anti-inflammatory properties of anesthetic agents
Authors: Cruz Fernanda Ferreira , Rocco Patricia Rieken Macedo , Pelosi Paolo 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Facing the ongoing challenge of the febrile young infant
Authors: DePorre Adrienne G. , Aronson Paul L. , McCulloh Russell J. 
Published: March 2017

AbstractThis article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2017. Other selected articles can be found online at http://ccforum.com/series/annualupdate2017. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901.
Superreplication of Financial Derivatives via Convex Programming
Authors: Kahalé Nabil 
Published: March 2017

We give a method based on convex programming to calculate the optimal superreplicating and subreplicating prices and corresponding hedging portfolios of a financial derivative in terms of other financial derivatives in a discrete-time setting. Our method produces a model that matches the superreplicating (or subreplicating) price within an arbitrary precision and is consistent with the other financial derivatives prices. Applications include robust replication in terms of call prices with various strikes and maturities of forward start options, volatility and variance swaps and derivatives, cliquet calls, barrier options, and lookback and Asian options. Numerical examples show that, in some cases, the best superreplicating and/or subreplicating prices are within 10% of the price obtained by a standard model but considerably differ from it in other cases. Our method can incorporate bid-ask spreads, interest rates and dividends, and various limitations to the diffusion model. The supplementary material is available at https://doi.org/10.1287/mnsc.2017.2786 . This paper was accepted by Gustavo Manso, finance.
Meta-analytics: tools for understanding the statistical properties of sports metrics
Authors: Franks Alexander M. , D’Amour Alexander , Cervone Daniel , Bornn Luke 
Published: March 2017

AbstractIn sports, there is a constant effort to improve metrics that assess player ability, but there has been almost no effort to quantify and compare existing metrics. Any individual making a management, coaching, or gambling decision is quickly overwhelmed with hundreds of statistics. We address this problem by proposing a set of “meta-metrics”, which can be used to identify the metrics that provide the most unique and reliable information for decision-makers. Specifically, we develop methods to evaluate metrics based on three criteria: (1) stability: does the metric measure the same thing over time (2) discrimination: does the metric differentiate between players and (3) independence: does the metric provide new information? Our methods are easy to implement and widely applicable so they should be of interest to the broader sports community. We demonstrate our methods in analyses of both NBA and NHL metrics. Our results indicate the most reliable metrics and highlight how they should be used by sports analysts. The meta-metrics also provide useful insights about how to best construct new metrics that provide independent and reliable information about athletes.
Deriving classifier word order typology, or Greenberg’s Universal 20A and Universal 20
Authors: Her One-Soon 
Published: March 2017

Abstract
The word order typology of numerals (Num), classifier or measure word (C/M), and noun (N) put forth by Greenberg (1990 [1972], Numerical classifiers and substantival number: Problems in the genesis of a linguistic type. In Keith Denning & Suzanne Kemmer (eds.),
Research into the Predictive Effect of TEG in the Changes of Coagulation Functions of the Patients with Traumatic Brain Hemorrhage
Authors: Liu Huanqiu , Li Ji , Yu Jinlu , Yuan Tong 
Published: March 2017

Abstract
To analyze the predictive effect of thrombelastogram (TEG) in the changes of coagulation functions of patients with traumatic brain hemorrhage, as well as to provide a practice basis for clinical guidance. 54 cases were observed from Aug. 2013–Oct. 2014. All patients received a TEG test 1d, 3d and 7d after traumatic injury. According to the statistical analysis, the comparison among the aforementioned coagulation function parameters in each group of patients, K, α and Ma all had significant differences. In the comparison between different time points in the same group, there was still a significant difference. Compared to the patients, the changes of R and K reached the lowest at 1d and the highest at 3d, but there was no significant difference between two groups at 7d. The changes of α and Ma reached its highest at 1d and the lowest at 3d after traumatic injury, but there was no significant difference at 7d. There was some difference in changes of coagulation functions between all groups. The former was more serious and the changes of coagulation functions had certain regularity, i.e., after traumatic injury, 1d showed a hypercoagulable state; 3d showed a hypocoagulable state; the coagulation functions of 7d returned to normal.
Endoscopic ultrasound in the diagnosis of
mediastinal diseases
Authors: Wang Zhiguo , Jiang Chunmeng 
Published: March 2017

Abstract
EUS is a useful tool for diagnosis of mediastinal
diseases. EUS-FNA plays an important role in staging
of lung cancer and in tissue acquisition in patients with
mediastinal masses. In this review, the following issues
will be addressed: EUS-FNA and EBUS-TBNA, metastatic
mediastinal lymph nodes diagnosed by EUS, EUS in
assessment of mediastinal lymph node status for staging
of lung cancer, mediastinal lymphoma diagnosed by EUS,
sarcoidosis and tuberculosis diagnosed by EUS.
A configuração do Neorregionalismo Brasileiro
Authors: De Oliveira Brito Herasmo Braga 
Published: March 2017

Este estudo tem como objetivo analisar a configuração literária do Neorregionalismo Brasileiro. No caso específico do artigo iremos nos pautar apenas na questão do espaço não entendido apenas como mera descrição física. Abordamos o espaço como elemento não só de composição de análise para a comprovação do neorregionalismo, mas, principalmente, como agente de relevante contribuição para o desenvolvimento das experiências dos personagens, em especial as femininas. Utiliza-se para estudos da caracterização do Neorregionalismo Brasileiro a obra Galiléia de Ronaldo Correia de Brito. A presente pesquisa caracteriza-se, essencialmente, como bibliográfica. Utilizando-se como base os seguintes autores: Araújo (2010), Bachelard (1993), Bakhtin (2011), Bueno (2006), Candido (2000, 2006), Chiappini (2014), Williams (1989). Buscou-se, primeiro, a fundamentação necessária para caracterizar essa nova tendência literária brasileira.
Trends in Medical and Nonmedical Use of Prescription Opioids Among US Adolescents: 1976–2015
Authors: McCabe Sean Esteban , West Brady T. , Veliz Phil , McCabe Vita V. , Stoddard Sarah A. , Boyd Carol J. 
Published: March 2017

OBJECTIVES:
Most US studies of national trends in medical and nonmedical use of prescription opioids have focused on adults. Given the limited understanding in these trends among adolescents, we examine national trends in the medical and nonmedical use of prescription opioids among high school seniors between 1976 and 2015.

METHODS:
The data used for the study come from the Monitoring the Future study of adolescents. Forty cohorts of nationally representative samples of high school seniors (modal age 18) were used to examine self-reported medical and nonmedical use of prescription opioids.

RESULTS:
Lifetime prevalence of medical use of prescription opioids peaked in both 1989 and 2002 and remained stable until a recent decline from 2013 through 2015. Lifetime nonmedical use of prescription opioids was less prevalent and highly correlated with medical use of prescription opioids over this 40-year period. Adolescents who reported both medical and nonmedical use of prescription opioids were more likely to indicate medical use of prescription opioids before initiating nonmedical use.

CONCLUSIONS:
Prescription opioid exposure is common among US adolescents. Long-term trends indicate that one-fourth of high school seniors self-reported medical or nonmedical use of prescription opioids. Medical and nonmedical use of prescription opioids has declined recently and remained highly correlated over the past 4 decades. Sociodemographic differences and risky patterns involving medical and nonmedical use of prescription opioids should be taken into consideration in clinical practice to improve opioid analgesic prescribing and reduce adverse consequences associated with prescription opioid use among adolescents.
Microcompression of brittle and anisotropic crystals: recent advances and current challenges in studying plasticity in hard materials
Authors: Korte-Kerzel Sandra 
Published: March 2017

AbstractRecent years have seen an increased application of small-scale uniaxial testing—microcompression—to the study of plasticity in macroscopically brittle materials. By suppressing fast fracture, new insights into deformation mechanisms of more complex crystals have become available, which had previously been out of reach of experiments. Structurally complex intermetallics, metallic compounds, or oxides are commonly brittle, but in some cases extraordinary, though currently mostly unpredictable, mechanical properties are found. This paper aims to give a survey of current advances, outstanding challenges, and practical considerations in testing such hard, brittle, and anisotropic crystals.
Temporal dimensions in Notes on Manuscripts and Old Books in Moldavia, I–IV, a corpus edited by I. Caproșu and E. Chiaburu
Authors: Lupu Maria 
Published: March 2017

This article is part of a broader research regarding the evolution of mentalities in the period starting with the 16th century, the aim of the present research being to identify and discuss the ways in which people in those days perceived time.
Our research focused on the material provided by the marginal notes—with a value of their own—made by readers on the pages of manuscripts from Moldavia over the span of more than 400 years. The main instruments we have employed are analysis and synthesis, from a diachronic perspective, from particular to general, by means of the inductive method.
As a result, an image has been shaped of the means by which the event, as an element of time, was perceived and rendered, and of the way in which time becomes the fundamental landmark of life, the one that comprises, marks, and generates the entire reality.
Aspectos históricos e as propostas educacionais do movimento dos trabalhadores rurais sem-terra no Brasil contemporâneo – um compromisso político com as transformações sociais!
Authors: Bauer Carlos 
Published: March 2017

Este trabalho tem como finalidade lançar um olhar crítico sobre umdos principais organismos políticos criados pelos trabalhadores ruraisbrasileiros, no caso o Movimento dos Trabalhadores Rurais Sem-Terra(MST). O MST é estudado no desenvolvimento dos seus princípioseducacionais que incluem o trabalho de formação e de conscientizaçãopolítica, tendo como marco histórico a luta contra a ditadura militar e a democratização do Estado em nosso país. De fato, o MST vemocupando um lugar de destaque, colocando-se como um dos legítimosinterlocutores dos setores populares no processo de disputa da hege-monia política em curso na sociedade brasileira. Esse reconhecimentonos parece relevante, principalmente se levarmos em consideração osaspectos e os princípios educativos dos movimentos sociais. Assim,estamos preocupados em estudar, numa dimensão histórica e política,o seu papel na construção da contra-hegemonia cultural e, também,reunir subsídios que permitam aos interessados refletir sobre as rela-ções entre o MST e as fecundas aspirações que nutrem pela educação.
Effect of the framework material on the final color of all-ceramic restorations
Authors: Borba Márcia , Sonza Queli Nunes , Della Bona Álvaro 
Published: March 2017

OBJECTIVES: to evaluate the effect of the type of ceramic framework material on the final color of all-ceramic restorations. The hypotheses tested were: (1) the final color of the restoration is different than the porcelain shade selected initially to veneer the framework and (2) different framework materials result in different colors of all-ceramic restorations. METHODS: Steel models simulating abutment teeth were used to design all-ceramic fixed partial dentures (FPDs). The FPDs were produced using three different framework materials (n=8): (YZ) yttria partially stabilized tetragonal zirconia polycrystal (LAVA, 3M); (IZ) glass-infiltrated alumina/zirconia (Vita In-Ceram Zirconia); (AL) polycrystalline alumina (Vita In-Ceram AL). Each framework was veneered with the recommended porcelain, VM9 for YZ and VM7 for IZ and AL groups (Vita). The porcelain shade used was 2M2. A uniform thickness of 1.2 mm of porcelain was applied around the retainers. The color difference (ΔE) and lightness difference (ΔL) between the selected porcelain shade (2M2) and the color of the final restoration were obtained using a clinical spectrophotometer (VITA Easyshade). Statistical analysis was performed using One-Way ANOVA and Tukey’s test (α=0.05). RESULTS: The ΔE mean values, standard deviation and statistical ranking for the experimental groups were: (YZ) 2.38 ± 0.44b; (IZ) 2.92 ± 0.67ab; (AL) 3.43 ± 0.84a. AL group showed the highest ΔE and ΔL mean values. IZ showed an intermediate ΔE value and statistically similar to AL and YZ groups. There was no significant difference between ΔL values for YZ and IZ groups. CONCLUSION: Although the color difference between all experimental groups and the porcelain shade selected to veneer the restorations could be visually detected (ΔE>1.0), only AL showed a difference above the clinical threshold (ΔE>3.0). Thus, the first study hypothesis was partially accepted. In addition, the type of framework ceramic influenced the final restoration color, accepting the second study hypothesis.
Influence of photoactivation protocol and ceramic thickness on mechanical properties of cementation agents
Authors: Oliveira Bárbara Malta Neves , Alves Karime Botelho , Ambrosano Gláucia Maria Bovi , Lima Débora Alves Nunes leite , Baron Giselle Maria Marchi , Aguiar Flávio Henrique Baggio , Giorgi Maria Cecília Caldas 
Published: March 2017

The objective of this work was to evaluate the influence of photoactivation protocol and ceramic thickness on the Knoop microhardness (KHN) and the diametrical tensile strength (DTS) of a dual resin cement (Rely X ARC 3M ESPE (RL)) and a low viscosity composite resin (Filtek Z350 Flow 3M ESPE (Z)). Thereunto, cementation agents were photoactivated under ceramic discs of lithium disilicate with thickness of 1 and 2mm, and a glass slide (control group). The photoactivation was performed with halogen light-curing unit in continuous mode (XL 3000 3M Espe,) (XL) 500 mW/cm2 X 38 s, and with third generation LED light-curing unit (Valo Ultradent) in Standard mode (S) 1000 mW/cm2 X 19 s and Plasma Emulation mode (PE) 3200 mW/cm2 X 6 s, all them providing approximately 19 J/cm2. For KHN measurement, samples (5mm X 1mm) were made (n=8) and submitted to the KHN test on the top surface under a load of 10g applied for 10 seconds. For the DTS (n=8), samples (5mm X 3mm) were made and submitted to a compressive load of 0.5 mm/s until fracture. The data obtained were submitted to the statistical analysis. For KHN, there was statistically significant effect for interactions cementation agent X ceramic thickness, where RL presented higher values of KHN than Z. Comparing inside of cementation agent, RL presented higher values of KHN when photoactivated under 1 mm of ceramic thickness, different from the others. For Z, there was no statistically significant difference between different thickness and the control. The interaction cementation agent X photoactivation protocol was also significant, where for all the photoactivation protocols RL presented higher values of KHN than Z. For the cementation agent there was no significant difference in the values of KHN in all the photoactivation protocols for RL. For Z, the higher values of KHN were obtained by XL protocol and the lower values by S. For DTS, there was significant effect for the interaction cementation agent X photoactivation protocol, where in the photoactivation protocol factor, RL presented higher DTS when photoactivated by XL protocol. For cementation agent factor, the higher values of DTS for RL were obtained with XL, and the lower ones with S. For Z, similar values of DTS were obtained among photoactivation protocols evaluated. It was possible conclude that ceramic thickness and the photoactivation protocols exerted influence on the mechanical properties of cementation agents evaluated.