bluuebunny/crossref_metadata_2025_split huggingface dataset:
ВОЗМОЖНОСТИ ТЕЛЕМЕДИЦИНЫ ДЛЯ НАБЛЮДЕНИЯ ЗА ПАЦИЕНТАМИ С СИНДРОМОМ СТАРЧЕСКОЙ АСТЕНИИ
Authors: Айдумова О.Ю. , Гаранин А.А. 
Published: October 2024

В статье представлен обзор литературы за последние 10 лет по применению возможностей телемедицины при наблюдении за пациентами с синдромом старческой астении. Рассмотрены актуальность и обоснованность реализации медицинской помощи с использованием телемедицинских технологий пациентам с синдромом старческой астении. Приведены примеры наиболее удачных решений при телемониторинге выбранной когорты пациентов, а также рассмотрены как положительные стороны, так и недостатки данных решений. Рассмотрены этические моменты дистанционного наблюдения за пожилыми пациентами, а также сложности внедрения телемедицинских технологий для постоянного мониторинга и ухода.
The article presents a review of the literature over the past 10 years on the use of telemedicine capabilities in the management of patients with a focus on patients with fragility. The relevance and validity of the implementation of medical care using telemedicine technologies for patients with fragility are considered. Examples of the most successful solutions for telemonitoring of the selected cohort of patients are given, and both the positive sides and disadvantages of these solutions are considered. The ethical aspects of telemonitoring elderly patients are considered, as well as the difficulties for the introduction of telemedicine technologies for continuous monitoring and care.
Pelatihan Perancangan dan Praktik Merakit Knockdown Furnitur di Desa Kertosari Kendal
Authors: Damastuti Prasiska , Sany Nukhbah , Adelia Eilsa , Damayanti Friska 
Published: October 2024

Desa Kertosari merupakan desa yang terletak di Kecamatan Singorojo, Kabupaten Kendal yang sebagian penduduknya menggantungkan hidupnya dan mendapatkan sumber penghasilan dari usaha dibidang furnitur. Terdapat kurang lebih 30 pelaku usaha yang bergerak di bidang furnitur. Produk furnitur yang dihasilkan masih dikerjakan secara manual dengan desain yang konvensional dan teknik yang sederhana. Untuk memenuhi pangsa pasar terkini, pelaku usaha harus mengutamakan desain dan kualitas produk yang dihasilkan. Oleh karena itu diperlukan upskilling bagi pelaku usaha furniture terkait perancangan dan perakitan knockdown furnitur sehingga dapat mengembangkan inovasi produk yang sesuai dengan masyarakat modern. Tahapan dalam kegiatan ini adalah identifikasi permasalahan, persiapan kegiatan, penyampaian materi dan evaluasi. Setelah diadakannya kegiatan pelatihan ini, para peserta telah memahami tahapan merancang sebuah produk furniture yang dapat dilihat pada hasil pretest dan posttest yang dikerjakan oleh peserta yang menunjukkan peningkatan dari yang semula skor 4,4 menjadi 5,7. Pengetahuan tersebut dapat digunakan oleh pelaku usaha untuk mengembangkan produk yang dihasilkan sehingga dapat meningkatkan penjualan produknya.
Incidência de cárie em crianças em idade escolar: uma revisão integrativa
Authors: Dos Santos Silva Ana Cecília , Barros Pimentel Thamires , Soares dos Anjos Raíssa 
Published: October 2024

Objetivo: Esta revisão integrativa teve como objetivo avaliar as principais incidências de cárie em crianças em idade escolar, no tocante, ao país, desenho, duração, amostra, sexo, idade e local onde foi realizada. Materiais e métodos: O levantamento bibliográfico foi realizado através do acesso online da BVS Brasil (Biblioteca Virtual em Saúde) e Pubmed (Medical Literature Analysis and Retrieval System on-line). Para a busca foram usados os seguintes descritores: “Dental Caries”, “Children”, “Babys”, “Sugar”, “Incidence”. Utilizaram-se as bases de dados: BBO, LILACS E PUBMED nos idiomas Português, Inglês e Espanhol entre os anos de 2019 a 2024. A maioria dos estudos foram realizados no Brasil, e um em Cuba. A amostra variou de 62 (sessenta e dois) a 27.305 (vinte e sete mil trezentos e cinco) pacientes e seu tempo de duração variou de 01 (um) a 06 (seis) anos. Resultados: As principais incidências de cárie encontradas foram: alimentos açucarados, fatores socioeconômicos, má higienização bucal. Conclusão: A conclusão desta revisão integrativa mostra uma alta ocorrência de incidência de cárie dentária em crianças de 04 (quatro) a 12 (doze) anos. Essas manifestações orais podem ser evitadas ou minimizadas através da inserção do Cirurgião Dentista, melhorias de políticas públicas e conscientização da higienização entre o vínculo familiar como parte integrante no atendimento ao paciente infantil, proporcionando seu bem-estar.
Radio Scrutiny of the X-Ray-weak Tail of Low-mass Active Galactic Nuclei: A Novel Signature of High-Eddington Accretion?
Authors: Paul Jeremiah D. , Plotkin Richard M. , Brandt W. N. , Ellis Christopher H. , Gallo Elena , Greene Jenny E. , Ho Luis C. , Kimball Amy E. , Haggard Daryl 
Published: October 2024

Abstract
The supermassive black holes (M
BH ∼ 106–1010
M
⊙) that power luminous active galactic nuclei (AGNs), i.e., quasars, generally show a correlation between thermal disk emission in the ultraviolet (UV) and coronal emission in hard X-rays. In contrast, some “massive” black holes (mBHs; M
BH ∼ 105–106
M
⊙) in low-mass galaxies present curious X-ray properties with coronal radiative output up to 100× weaker than expected. To examine this issue, we present a pilot study incorporating Very Large Array radio observations of a sample of 18 high-accretion-rate (Eddington ratios L
bol/L
Edd > 0.1), mBH-powered AGNs (M
BH ∼ 106
M
⊙) with Chandra X-ray coverage. Empirical correlations previously revealed in samples of radio-quiet, high-Eddington AGNs indicate that the radio–X-ray luminosity ratio, L
R/L
X, is approximately constant. Through multiwavelength analysis, we instead find that the X-ray-weaker mBHs in our sample tend toward larger values of L
R/L
X even though they remain radio-quiet per their optical–UV properties. This trend results in a tentative but highly intriguing correlation between L
R/L
X and X-ray weakness, which we argue is consistent with a scenario in which X-rays may be preferentially obscured from our line of sight by a “slim” accretion disk. We compare this observation to weak emission-line quasars (AGNs with exceptionally weak broad-line emission and a significant X-ray-weak fraction) and conclude by suggesting that our results may offer a new observational signature for finding high-accretion-rate AGNs.
An Analysis of the Complex and Compact Outflow Cavity Carved by HOPS 361-A in NGC 2071 IR
Authors: Karnath Nicole , Rubinstein Adam E. , Federman Samuel , Quillen Alice C. , Green Joel D. , Chambers Edward T. , Watson Dan M. , Megeath S. Thomas , Coudé Simon , Justen Matthias , Narang Mayank , Goldman Steve , Tobin John J. 
Published: October 2024

Abstract
We present a combined Stratospheric Observatory for Infrared Astronomy (SOFIA) and two-epoch Hubble Space Telescope (HST) study of the region NGC 2071 IR containing the outflow from the protostar HOPS 361-A (NGC 2071 IRS 1). New [O i] 63 μm spectra, taken with the German REciever for Astronomy at Terahertz frequencies (GREAT) instrument aboard SOFIA, trace the outflow, spectrally resolve line profiles, and give radial velocities of the far-IR emission to yield 3D kinematics, shock properties, and feedback properties. Proper motions and extinction values from HST give a more complete quasi-3D picture that we use to model shock speeds and densities. We identify 14 distinct features that show proper motions. Combined with the GREAT data, we estimate that HOPS 361-A has a mass outflow rate of 3.16 × 10−6
M
⊙ yr−1 with shock speeds up to 51 km s−1. The outflow force summed over all knots per area is measured to be 1.45 × 10−4
M
⊙ km−1 s−1 yr−1 and a power summed over all knotsper area of 2.37 × 10−2
M
⊙ s−3 dissipated assuming constant

M

̇

, with large uncertainties on the feedback values. The total [O i] luminosity using all SOFIA apertures encompassing the HOPS 361 clump is 0.7 L
⊙, corresponding to a mass outflow rate of 7 × 10−5
M
⊙ yr−1. This is the second 3D kinematic study of an outflow in NGC 2071 IR in the near- and far-IR regimes following Rubinstein et al. (2023). The SOFIA [O i] spectra add unique focus to the entrained gas connecting the recent episode of outflows from HOPS 361-A to the outflow cavity and the surrounding NGC 2071 IR star-forming environment.
Multiwavelength Investigation of γ-Ray Source MGRO J1908+06 Emission Using Fermi-LAT, VERITAS and HAWC
Authors: Acharyya A. , Adams C. B. , Bangale P. , Bartkoske J. T. , Benbow W. , Buckley J. H. , Christiansen J. L. , Chromey A. J. , Duerr A. , Errando M. , Falcone A. , Feng Q. , Foote G. M. , Fortson L. , Furniss A. , Hanlon W. , Hanna D. , Hervet O. , Hinrichs C. E. , Holder J. , Humensky T. B. , Jin W. , Kaaret P. , Kertzman M. , Kieda D. , Kleiner T. K. , Korzoun N. , Kumar S. , Lang M. J. , Lundy M. , Maier G. , McGrath C. E , Millard M. J. , Millis J. , Mooney C. L. , Moriarty P. , Mukherjee R. , Ning W. , Ong R. A. , Park N. , Pohl M. , Pueschel E. , Quinn J. , Rabinowitz P. L. , Ragan K. , Ribeiro D. , Roache E. , Ryan J. L. , Sadeh I. , Saha L. , Sembroski G. H. , Shang R. , Splettstoesser M. , Talluri A. K. , Tucci J. V. , Valverde J. , Vassiliev V. V. , Weinstein A. , Williams D. A. , Wong S. L. , Woo J. ,   The VERITAS Collaboration, Alfaro R. , Alvarez C. , Arteaga-Velázquez J. C. , Avila Rojas D. , Babu R. , Belmont-Moreno E. , Bernal A. , Caballero-Mora K. S. , Capistrán T. , Carramiñana A. , Casanova S. , Cotzomi J. , Coutiño de León S. , De la Fuente E. , Depaoli D. , Di Lalla N. , Diaz Hernandez R. , DuVernois M. A. , Espinoza C. , Fan K. L. , Fang K. , Fraija N. , García-González J. A. , Garfias F. , González M. M. , Goodman J. A. , Groetsch S. , Hernández-Cadena S. , Hinton J. , Huang D. , Hueyotl-Zahuantitla F. , Iriarte A. , Kaufmann S. , Kieda D. , Lee J. , León Vargas H. , Longinotti A. L. , Luis-Raya G. , Malone K. , Martínez-Castro J. , Matthews J. A. , Miranda-Romagnoli P. , Morales-Soto J. A. , Moreno E. , Mostafá M. , Nellen L. , Pérez-Pérez E. G. , Rho C. D. , Rosa-González D. , Salazar H. , Sandoval A. , Schneider M. , Serna-Franco J. , Son Y. , Springer R. W. , Tibolla O. , Tollefson K. , Torres I. , Torres-Escobedo R. , Turner R. , Ureña-Mena F. , Varela E. , Wang X. , Zhou H. ,   The HAWC Collaboration, Eagle J. , Kumar S. ,   The Fermi-LAT Collaboration
Published: October 2024

Abstract
This paper investigates the origin of the γ-ray emission from MGRO J1908+06 in the GeV–TeV energy band. By analyzing the data collected by the Fermi Large Area Telescope, the Very Energetic Radiation Imaging Telescope Array System, and High Altitude Water Cherenkov, with the addition of spectral data previously reported by LHAASO, a multiwavelength study of the morphological and spectral features of MGRO J1908+06 provides insight into the origin of the γ-ray emission. The mechanism behind the bright TeV emission is studied by constraining the magnetic field strength, the source age, and the distance through detailed broadband modeling. Both spectral shape and energy-dependent morphology support the scenario that inverse Compton emission of an evolved pulsar wind nebula associated with PSR J1907+0602 is responsible for the MGRO J1908+06 γ-ray emission with a best-fit true age of T = 22 ± 9 kyr and a magnetic field of B = 5.4 ± 0.8 μG, assuming the distance to the pulsar d
PSR = 3.2 kpc.
An Eddington-limited Accretion Disk Wind in the Narrow-line Seyfert 1 PG 1448+273
Authors: Reeves J. N. , Braito V. , Luminari A. , Porquet D. , Laurenti M. , Matzeu G. , Lobban A. , Hagen S. 
Published: October 2024

Abstract
PG 1448+273 is a luminous, nearby (z = 0.0645), narrow-line Seyfert 1 galaxy, which likely accretes close to the Eddington limit. Previous X-ray observations of PG 1448+273 with XMM-Newton in 2017 and NuSTAR in 2022 revealed the presence of an ultrafast outflow, as seen through its blueshifted iron (Fe) K absorption profile, where the outflow velocity appeared to vary in the range 0.1−0.3c. In this work, new X-ray observations of PG 1448+273 are presented, in the form of four simultaneous XMM-Newton and NuSTAR observations performed in 2023 July and August. The X-ray spectra appeared at a similar flux in each observation, making it possible to analyze the mean 2023 X-ray spectrum at high signal-to-noise ratio. A broad (σ = 1 keV) and highly blueshifted (E = 9.8 ± 0.4 keV) Fe K absorption profile is revealed in the mean spectrum. The profile can be modeled by a fast, geometrically thick accretion disk wind, which reveals a maximum terminal velocity of v
∞ = −0.43 ± 0.03c, one of the fastest known winds in a nearby active galactic nucleus. As a result, the inferred mass outflow rate of the wind may reach a significant fraction of the Eddington accretion rate.
Clinical validation of the early embryo viability assessment system: Analysis for the blastocyst morphology and pregnancy outcomes
Authors: Hop Vu D , Cuong An M , Anh Phi T T , Huong Nguyen T L , Hoang Le , Hanh Nguyen V 
Published: October 2024

Objective:
To determine the relationship between the early embryo viability assessment (EEVA) and blastocyst morphological parameters and pregnancy outcomes.

Methods:
This retrospective cohort study was conducted on 291 intracytoplasmic sperm injection cycles including 2 522 embryos with indications of prolonging embryo culture to the blastocyst stage in the Genea embryo review incubator, and 511 single vitrified- warmed blastocyst transfer cycles from January 2020 to June 2023. The EEVA system produced an EEVA score from E1 (best) to E5 (worse) for the potential of blastocyst formation. Blastocyst morphology was evaluated. The association between the EEVA score and each type of blastocyst morphology, implantation rate, clinical pregnancy, and ongoing pregnancy were assessed using generalized estimating equations.

Results:
The inner cell mass A (ICM A), trophectoderm A (TE A), blastocoele expansion degree of 3, 4, 5, 6, 7 rates were higher with lower the EEVA score. The adjusted odd ratio (aOR) (E5 vs E1) was 0.3 for ICM A, 0.174 for TE A and 0.210 for BL3, 4, 5, 6, 7 (all P<0.001), suggesting a significant association between lower EEVA scores and improved embryo quality. The implantation, clinical pregnancy, and ongoing pregnancy rate were also higher with lower the EEVA score. The aOR of E5 vs E1 was 0.245 for implantation, 0.185 for clinical pregnancy and 0.200 for ongoing pregnancy rate (P<0.001).

Conclusions:
There were associations between blastocyst morphology, pregnancy outcome and EEVA scores. The good blastocyst morphology and pregnancy outcomes are higher with lower the EEVA score.
N-acetylcysteine and zinc sulphate abate di-2-ethylhexyl phthalate-mediated reproductive dysfunction in rats: Focus on oxidative and sex hormone receptors mechanisms
Authors: Emojevwe Victor Oghenekparobo , Oyovwi Mega Obukohwo , Adewole Kayode Ezekiel , Ohwin Peggy Ejiro , Akinola Adeniran Oluwadamilare , Naiho Alexander Obidike , Nwangwa Eze Kingsley , Omo-Idonije Victor , Lade-Ige Motunrayo , Ben-Azu Benneth 
Published: October 2024

Objective:
To investigate the potential of N-acetylcysteine (NAC) and zinc sulphate (ZnSO4) in mitigating reproductive dysfunction caused by di-2-ethylhexyl phthalate (DEHP) in rats and to understand the underlying mechanisms, specifically oxidative stress and sex hormone receptor activity.

Methods:
Thirty-five male Wistar rats were randomly divided into five equal groups (n=7 per group). Group 1 was administered 0.5 mL of distilled water and served as the control group. Group 2 was given only DEHP (750 mg/kg/day), while group 3, 4 and 5 were given DEHP (750 mg/kg/day) plus NAC (100 mg/kg/day), DEHP (750 mg/kg/day) plus ZnSO4 (0.5 mg/kg/day), and DEHP (750 mg/kg/day) plus NAC (100 mg/kg/day) as well as ZnSO4 (0.5 mg/kg/day), respectively. All treatments lasted for 21 days. Samples were obtained after the rats were sacrificed, and hormones levels in the serum and markers of oxidative stress in the testicles were analyzed using the enzyme-linked immunosorbent assay. The amount of androgen receptors in the testicles was determined by immunohistochemistry, and the susceptibility of testosterone and DEHP to bind to androgen receptor and 5α-reductase was determined by molecular docking studies.

Results:
DEHP decreased reproductive hormones, testicular antioxidant enzymes, increased malondialdehyde levels, and negatively impacted histology of the pituitary and testes. NAC or ZnSO4 treatment showed a marked improvement in testicular antioxidant status and hormone levels, as well as a positive effect on the histology of the pituitary and testes. The combination of both treatments appeared to be more effective. The affinity of DEHP to bind to androgen receptors may lead to disruption of androgen receptor signaling, which can further result in dysfunction of hormones related to androgen. However, NAC is more likely to form stronger binding interactions with follicle stimulating hormone and luteinizing hormone receptors, as well as gonadotropin-releasing hormone receptors, when compared to DEHP.

Conclusions:
The possibility that NAC and ZnSO4 could downregulate DEHP-induced sex hormone changes is suggested by their potential to reduce toxicity.
Resolution of sperm quality impairment following SARS-CoV-2 infection: A prospective study
Authors: Derakhshan Marzieh , Derakhshan Maryam , Naghshineh Elham , Movahedi Minoo , Ghasemi-Tehrani Hatav , Bamarinejad Fatemeh , Bamarinejad Atefeh , Omidvar Zeinab 
Published: October 2024

Objective:
To investigate the length of time required to resolve COVID-19 effects on semen quality and DNA integrity.

Methods:
A prospective cohort study was conducted among 42 men who tested positive for SARS-CoV-2 and underwent semen analysis at baseline and four months’ post-recovery. Semen samples were collected and evaluated for macroscopic and microscopic parameters, sperm chromatin maturation, and DNA fragmentation.

Results:
The mean age of participants was 37(±7) years, and 14% had normozoospermia at baseline. After a four-month recovery from COVID-19, 48% of patients had normozoospermia. Sperm count, motility, and morphology increased significantly, while sperm DNA fragmentation and sperm chromatin maturation decreased significantly post-recovery from COVID-19.

Conclusions:
Sperm parameters improve after a four-month recovery from COVID-19. The findings indicate significant improvements in sperm count, motility, morphology, DNA fragmentation, and chromatin maturation after a four-month recovery period.
Effect of telehealth education on women’s knowledge regarding risk factors and early detection of breast cancer
Authors: Abd Elkodoos Rehab Fouad , Ebrahim Mona Mohamed , Abd El Kader Aziza Ibrahim , Abdallah Lamiaa Saad 
Published: October 2024

Background
The most frequent cancer that affects women worldwide is breast cancer (BC). Through comprehension of risk factors and early detection approaches, women can become more adept at managing their journey toward breast health.

Aim
The aim of the study was to evaluate the effect of telehealth education on women’s knowledge regarding risk factors and early detection of BC.

Design
A quasi-experimental (pre- and post test) design was used to achieve the current study aim.

Setting
The current study was carried out at family health centers in Cairo City, Egypt.

Sample
A purposive sample of 300 women was recruited for the current study.

Tools
Two tools were used for data collection. Tool (I): Demographic and medical-related data form and Tool (II) BC Knowledge Questionnaire.

Results
The current findings disclosed that there were statistically significant differences between all knowledge dimensions’ mean scores of BC risk factors related to knowledge pre-, post-, and follow-up telehealth sessions (P value= 0.0001). Also, the study finding indicated that 73% of participants got a satisfactory knowledge level regarding BC risk factors and early detection after sessions, which increased to 86.7% after 3 months.

Conclusion
The implementation of telehealth education has a significant effect on improving women’s knowledge regarding BC risk factors and early detection.

Recommendations
Promotion and development of telehealth education programs to raise women’s knowledge about BC risk factors and early detection
Awareness and attitude of genetic testing among relatives and patients with breast cancer
Authors: Mohamed Amany Moustafa , Elsawi Khairia Abu-bakr , Ali Shaimaa Raafat , Mohamed Ahmed Abdelhafeez 
Published: October 2024

Background
Genetic testing is an important medical tool for assessing many inheritable diseases and cancers. It plays a vital role in diagnosing patients before symptoms, which helps decrease the severity of outcomes and promote quality of life

Aim
To assess the awareness and attitude of genetic testing of breast cancer gene 1 (BRCA1) and breast cancer gene 2 (BRCA2) among first-degree relatives (FDR) and patients with breast cancer.

Design
A descriptive exploratory research design was used.

Sample
A convenient sample of 100 participants were divided into 50 patients with confirmed diagnosis of breast cancer and 50 FDR of patients with breast cancer.

Setting
The study was conducted at the Center of Clinical Oncology and Nuclear Medicine in one of Cairo University’s affiliated hospitals.

Tools
Four tools were used to collect data: Tool (a): Patients’ Personal and Medical Background Form (PPMBF), Tool (b): FDR of Patients with Breast Cancer Personal and Medical Background Form (FRPBCPMBF). Tool (c) Awareness of Genetic Testing Structured Questionnaire (AGTSQ). Tool (e): Attitude toward Genetic Testing Structured Questionnaire (ATGTSQ)

Results
Of the patients, 86% had an unsatisfactory level of awareness of genetic testing of BRCA1 and BRCA2, 64% of patients had a neutral attitude toward genetic testing of BRCA1 and BRCA2, 32% of FDRs had a satisfactory level of awareness of genetic testing of BRCA1 and BRCA2, and 60% of FDRs had a neutral attitude toward genetic testing BRCA1 and BRCA2.

Conclusion
Awareness of genetic testing of BRCA1 and BRCA2 is very important to detect genetic mutation and improve prognosis. FDR and patients with breast cancer had an unsatisfactory level of awareness and a neutral attitude toward genetic testing of BRCA1 and BRCA2.

Recommendations
FDR and patients with breast cancer must undergo BRCA1 and BRCA2 genetic testing to exclude genetic mutation. Awareness of FDR of patients with breast cancer should be raised regarding genetic testing of BRCA1 and BRCA2.
Effect of nursing intervention on reducing complications for patients with ruptured esophageal varices
Authors: Mobed Kawther B. , Hashem Eman M. , Elhafez Maha N.A. 
Published: October 2024

Background
One of the most common complications in people with liver cirrhosis is esophageal varices, and they do not exhibit any symptoms until they bleed.

Aim
Evaluate the effect of nursing intervention on reducing complications for patients with ruptured esophageal varices.

Design
A quasi-experimental research design was used.

Setting
This study was conducted in the Medical Department at Al-Rajhi Liver Hospital at Assiut University.

Patients
A convenient sample of 30 nurses and a purposive sample of 60 patients who were divided equally into study and control groups.

Tools
A structured interview questionnaire sheet for nurses, a structured interview questionnaire sheet for patients, Glasgow–Blatchford Bleeding scale, and patients’ complications assessment sheet.

Results
There was a significant enhancement of nurses’ knowledge and practice mean scores after the implementation of the nursing intervention (25.53±2.25, 166.53±15.51) than before (13.76±5.83, 95.3±26.38), respectively, with a statistically significant difference. There was a statistically significant difference between the study and control group patients related to complications of shock, hemodynamic instability, and disturbed conscious level with a P value less than 0.001.

Conclusion
There was a significant improvement in nurses’ knowledge and practice after the implementation of nursing intervention, which reflected a decrease in patients’ complications.

Recommendations
Regular training programs for nurses and preparing instructions booklet for patients with esophageal varices.