bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of transport pricing policy on individual energy consumption: a modeling case study in Kumamoto
Authors: Yin Yanhong , Chen Tie , Du Zhigang , Mizokami Shoshi 
Published: November 2015

SummaryTo investigate the impact of traffic pricing policies on energy consumption, this study shows a microeconomic quantitative analysis scheme to simulate individual consumption behaviors from a microeconomic viewpoint. Energy consumption is estimated based on individual demand of non‐mobility goods and mobility goods under nine policy scenarios based on strategies of gasoline tax adding and mass transit fare reduction independently or combined. Results show that gasoline tax adding has strong effects on consumption behaviors. Energy consumption reduces mostly because of less consumption of non‐mobility goods and car trips. However, policy of mass transit fare reduction has limited impact on energy saving because consumption of non‐mobility goods and mass transit trips increases, but the number of car trips decline by only a small percentage. Comparing with single‐type policy, policies that combined gasoline tax adding and mass transit fare reduction show less energy consumption. Findings suggest that policies that increase cost of car trips, such as gasoline tax adding, are very helpful to reduce the consumption of non‐mobility goods and car trips, which contribute to less energy consumption. However, reducing cost of mass transit trips suggests limited effect on energy saving. Copyright © 2015 John Wiley & Sons, Ltd.
Hybrid simulation approach incorporating microscopic interaction along with rigid body degrees of freedom for stacking between base pairs
Authors: Mondal Manas , Halder Sukanya , Chakrabarti Jaydeb , Bhattacharyya Dhananjay 
Published: November 2015

ABSTRACTStacking interaction between the aromatic heterocyclic bases plays an important role in the double helical structures of nucleic acids. Considering the base as rigid body, there are total of 18 degrees of freedom of a dinucleotide step. Some of these parameters show sequence preferences, indicating that the detailed atomic interactions are important in the stacking. Large variants of non‐canonical base pairs have been seen in the crystallographic structures of RNA. However, their stacking preferences are not thoroughly deciphered yet from experimental results. The current theoretical approaches use either the rigid body degrees of freedom where the atomic information are lost or computationally expensive all atom simulations. We have used a hybrid simulation approach incorporating Monte‐Carlo Metropolis sampling in the hyperspace of 18 stacking parameters where the interaction energies using AMBER‐parm99bsc0 and CHARMM‐36 force‐fields were calculated from atomic positions. We have also performed stacking energy calculations for structures from Monte‐Carlo ensemble by Dispersion corrected density functional theory. The available experimental data with Watson–Crick base pairs are compared to establish the validity of the method. Stacking interaction involving A:U and G:C base pairs with non‐canonical G:U base pairs also were calculated and showed that these structures were also sequence dependent. This approach could be useful to generate multiscale modeling of nucleic acids in terms of coarse‐grained parameters where the atomic interactions are preserved. This method would also be useful to predict structure and dynamics of different base pair steps containing non Watson–Crick base pairs, as found often in the non‐coding RNA structures. © 2015 Wiley Periodicals, Inc. Biopolymers 105: 212–226, 2016.
Mitochondrial protein‐derived cryptides: Are endogenous N‐formylated peptides including mitocryptide‐2 components of mitochondrial damage‐associated molecular patterns?
Authors: Marutani Takayuki , Hattori Tatsuya , Tsutsumi Koki , Koike Yusuke , Harada Akihiko , Noguchi Kosuke , Kiso Yoshiaki , Mukai Hidehito 
Published: November 2015

ABSTRACTRecently, much attention has been paid to “nonclassical” bioactive peptides, which are fragmented peptides simultaneously produced during maturation and degradation of various functional proteins. We identified many fragmented peptides derived from various mitochondrial proteins including mitocryptide‐1 and mitocryptide‐2 that efficiently activate neutrophils. These endogenous, functionally active, fragmented peptides are referred to as “cryptides.” Among them, mitocryptide‐2 is an N‐formylated cryptide cleaved from mitochondrial cytochrome b that is encoded in mitochondrial DNA (mtDNA). It is known that 13 proteins encoded in mtDNA are translated in mitochondria as N‐formylated forms, suggesting the existence of endogenous N‐formylated peptides other than mitocryptide‐2. Here, we investigated the effects of N‐formylated peptides presumably cleaved from mtDNA‐encoded proteins other than cytochrome b on the functions of neutrophilic cells to elucidate possible regulation by endogenous N‐formylated cryptides. Four N‐formylated cryptides derived from cytochrome c oxidase subunit I and NADH dehydrogenase subunits 4, 5, and 6 among 12 peptides from mtDNA‐encoded proteins efficiently induced not only migration but also β‐hexosaminidase release, which is an indicator of neutrophilic phagocytosis, in HL‐60 cells differentiated into neutrophilic cells. These activities were comparable to or higher than those induced by mitocryptide‐2. Although endogenous N‐formylated peptides that are contained in mitochondrial damage‐associated molecular patterns (DAMPs) have yet to be molecularly identified, they have been implicated in innate immunity. Thus, N‐formylated cryptides including mitocryptide‐2 are first‐line candidates for the contents of mitochondrial DAMPs to promote innate immune responses. © 2015 Wiley Periodicals, Inc. Biopolymers (Pept Sci) 106: 580–587, 2016.
Beyond the Physical Incident Model: How Children Living with Domestic Violence are Harmed By and Resist Regimes of Coercive Control
Authors: Katz Emma 
Published: November 2015

This article begins to build knowledge of how non‐violent coercive controlling behaviours can be central to children's experiences of domestic violence. It considers how children can be harmed by, and resist, coercive controlling tactics perpetrated by their father/father‐figure against their mother. Already, we know much about how women/mothers experience non‐physical forms of domestic violence, including psychological/emotional/verbal and financial abuse, isolation and monitoring of their activities. However, this knowledge has not yet reached most research on children and domestic violence, which tends to focus on children's exposure to physical violence. In this qualitative study, 30 participants from the UK, 15 mothers and 15 of their children (most aged 10–14) who had separated from domestic violence perpetrators, participated in semi‐structured interviews. All participants were living in the community. Using the ‘Framework’ approach to thematically analyse the data, findings indicated that perpetrators'/fathers' coercive control often prevented children from spending time with their mothers and grandparents, visiting other children's houses and engaging in extra‐curricular activities. These non‐violent behaviours from perpetrators/fathers placed children in isolated, disempowering and constrained worlds which could hamper children's resilience and development and contribute to emotional/behavioural problems. Implications for practice and the need to empower children in these circumstances are discussed. Copyright © 2015 John Wiley & Sons, Ltd.‘Considers how children can be harmed by, and resist, coercive controlling tactics perpetrated by their father/father‐figure against their mother’Key Practitioner MessagesChildren experiencing domestic violence may be affected by more than the physical violence perpetrated by one parent against the other.Children may be harmed by non-physical abusive behaviours inherent to coercive control-based domestic violence, including continual monitoring, isolation and verbal/emotional/psychological and financial abuses.Responsibility for the impacts on children of coercive control-based domestic violence should be placed with the perpetrator (usually fathers/father‐figures) and not with the victimised parent (usually mothers).
Segmenting initial fans of a new team: A taxonomy of sport early adopters
Authors: McDonald Heath , Leckie Civilai , Karg Adam , Zubcevic‐Basic Nives , Lock Daniel 
Published: November 2015

AbstractMarketers are interested in the first buyers of new products, given their important role in driving wider community adoption. This is especially the case for new entertainment products, like new or relocated sports teams who must quickly build fan connections and loyalty, given the importance of crowds and social networks in adding value to the entertainment experience. Fans choose to connect with sports teams for numerous reasons; however, fan development in the context of a new team has rarely been examined. This paper examines the diversity and similarity among inaugural fans of an expansion team. A large sample (n = 1724) was classified into five segments revealing how each varies in their brand associations, satisfaction, identification and involvement. By analysing key dimensions (relationship identifiers) that characterise how consumers connect with a new team, the authors provide new insights about the nature of consumers in the context of a new sports team. Furthermore, the five segments were found to be distinct cohorts, with sufficient variation between them to warrant variant marketing approaches to achieve the outcome of committed, long‐term fans. Copyright © 2015 John Wiley & Sons, Ltd.
Primary osteosarcoma of the breast: a case report
Authors: Crèvecoeur Julie , Jossa Véronique , Gennigens Christine , Parmentier Jean‐Claude , Crèvecoeur André 
Published: November 2015

Key Clinical MessageWe report a rare case of primary osteosarcoma of the breast in a patient who presented a calcified fibroadenoma one year before the appearance of the malignant lesion. We describe the follow‐up of the patient and the discovery of a similar osteosarcoma in the other breast one year later.
Formation of Gold Nanoparticle Size and Density Gradients via Bipolar Electrochemistry
Authors: Lundgren Anders , Munktell Sara , Lacey Matthew , Berglin Mattias , Björefors Fredrik 
Published: November 2015

AbstractBipolar electrochemistry is employed to demonstrate the formation of gold nanoparticle size gradients on planar surfaces. By controlling the electric field in a HAuCl4‐containing electrolyte, gold was reduced onto 10 nm diameter particles immobilized on pre‐modified thiolated bipolar electrode (BPE) templates, resulting in larger particles towards the more cathodic direction. As the gold deposition was the dominating cathodic reaction, the increased size of the nanoparticles also reflected the current distribution on the bipolar electrode. The size gradients were also combined with a second gradient‐forming technique to establish nanoparticle surfaces with orthogonal size and density gradients, resulting in a wide range of combinations of small/large and few/many particles on a single bipolar electrode. Such surfaces are valuable in, for example, cell‐material interaction and combinatorial studies, where a large number of conditions are probed simultaneously.
Fabrication of Li+‐Conductive Li2ZrO3‐Based Shell Encapsulated LiNi0.5Co0.2Mn0.3O2 Microspheres as High‐Rate and Long‐Life Cathode Materials for Li‐Ion Batteries
Authors: Wu Hao , Wang Zongyi , Liu Shengjie , Zhang Li , Zhang Yun 
Published: November 2015

AbstractThe front cover artwork is provided by the group of Prof. Yun Zhang and Prof. Hao Wu at the Sichuan University (Chengdu, China). The image shows the surface establishing ternary layered LiNi0.5Co0.2Mn0.3O2 microspheres with a fast‐Li+‐conductive Li2ZrO3 shell, using a facile pre‐coating approach towards high‐rate and long‐life lithium‐ion batteries. Read the full text of the Article at 10.1002/celc.201500303.
Accessing N‐Stereogenicity through a Double Aza‐Michael Reaction: Mechanistic Insights
Authors: Kohrt Sonja , Santschi Nico , Cvengroš Ján 
Published: November 2015

AbstractFurther development of the chemistry and applications of chiral compounds that possess configurationally stable stereogenic nitrogen atoms is hampered by the lack of efficient strategies to access such compounds in an enantiomerically pure form. Esters of propiolic acid and chiral alcohols were evaluated as cheap and readily available Michael acceptors in a diastereoselective synthesis of N‐stereogenic compounds by means of a double aza‐Michael conjugate addition. Diastereomeric ratios of up to 74:26 and high yields were achieved with (−)‐menthyl propiolate as a substrate. Furthermore, a detailed mechanistic investigation was undertaken to shed some light on the course of this domino transformation. Kinetic studies revealed that the protic‐solvent additive acts as a Brønsted acid and activates the ester toward the initial attack of the tetrahydrodiazocine partner. Conversely, acidic conditions proved unfavorable during the final cyclization step that provides the product.
Collective Synthesis and Biological Evaluation of Tryptophan‐Based Dimeric Diketopiperazine Alkaloids
Authors: Tadano Shinji , Sugimachi Yukihiro , Sumimoto Michinori , Tsukamoto Sachiko , Ishikawa Hayato 
Published: November 2015

AbstractA concise two one‐pot synthesis of WIN 64821, eurocristatine, 15,15′‐bis‐epi‐eurocristatine, ditryptophenaline, ditryptoleucine A, WIN 64745, cristatumin C, asperdimin, naseseazine A, and naseseazine B is detailed, based on a unique bioinspired dimerization reaction of tryptophan derivatives in aqueous acidic solution and a one‐pot procedure for the construction of diketopiperazine rings. Total yields of these alkaloid syntheses were from 10 up to 27 %. In addition, 1′‐(2‐phenylethylene)‐ditryptophenaline was synthesized by using three one‐pot operations. The studies detailed herein provided synthesized natural products for inhibitory activities of ubiquitin‐specific protease 7 (USP7) and foam cell formation in macrophages. The newly listed biological evaluation for tryptophan‐based dimeric diketopiperazine alkaloids discovered 15,15′‐bis‐epi‐eurocristatine, 1′‐(2‐phenylethylene)‐ditryptophenaline, and WIN 64745 as new drug candidates.
Recent Progress in Dehydro(genative) Diels–Alder Reaction
Authors: Li Wenbo , Zhou Liejin , Zhang Junliang 
Published: November 2015

AbstractIn recent years, remarkable progress has been made in dehydro or dehydrogenative Diels–Alder (D–A) reactions. This Minireview gives an overview of the major two strategies for dehydro(genative) Diels–Alder reactions, which differ in dehydrogenation and D–A cyclization sequence. Reactions in which D–A cycloaddition is followed by dehydrogenation are useful methods for the synthesis of various aromatic compounds, whereas advancements in dehydro genative procedures with oxidants or catalysts prior to D–A cycloaddition offer yet further new routes to functionalized cycloadducts. Recent leading findings are highlighted and the current state of the art, scope, and limitations of these processes are discussed in this Minireview.
Automatic detection of layout of color yarns of yarn‐dyed fabric. Part 2: Region segmentation of double‐system‐Mélange color fabric
Authors: Zhang Jie , Pan Ruru , Gao Weidong , Xu Bugao , Li Wei 
Published: November 2015

AbstractTo detect the layout of color yarns automatically, a novel projection‐based fabric segmentation method is proposed to segment the double‐system‐mélange color fabric into several regions, which can be seen as single‐system‐mélange color fabrics. This method consists of five main steps: (1) yarn skew detection, (2) fabric image projecting, (3) projection curve smoothing, (4) variance curve calculating, and (5) curve peak confirmation. Based on the acquisition fabric image, the skew angles of warp and weft yarns are detected by Hough transform first. The projection curves of L, a, and b channels in Lab color model are generated and smoothed by Savitzky–Golay filter. The variance curves of L, a, and b are then calculated, and the peaks corresponding to the regional boundaries in each curve are detected. The regional boundaries are confirmed by synthesizing the curve peaks of L, a, and b. The experimental and theoretical analysis proves that the proposed method can segment the double‐system‐mélange color fabric into regions with satisfactory accuracy and good robustness. © 2015 Wiley Periodicals, Inc. Col Res Appl, 41, 626–635, 2016
Research on filter selection method for broadband spectral imaging system based on ancient murals
Authors: Liang Jinxing , Wan Xiaoxia , Liu Qiang , Li Chan , Li Junfeng 
Published: November 2015

AbstractDigitization of cultural heritage protection has received considerable attention in heritage studies and spectral imaging technology has been playing an important role in this research. This article aims to study the technique of selecting optimal filter set to obtain ancient murals spectral image with high spectral and colorimetric accuracy based on the broadband spectral imaging system. The 330 Dunhuang murals mineral pigment color patches and the GretagMacbeth ColorChecker (CC) as well as 27 pieces of optical filters chosen as samples were examined. For each piece of filter, the three‐channel image was captured by the spectral imaging system. Then, 351 groups of six‐channel digital count images were acquired by arbitrary combinations of two among the 27 three‐channel digital count images. The pseudo‐inverse, principal component analysis, and R‐matrix methods were used to reconstruct the spectral reflectance from the six‐channel digital counts for each sample. Finally, this study identified the optimal filter set by evaluating the integrated error (TOTAL ERROR), which was calculated by normalizing the mean spectral root‐mean‐square error (RMS), mean spectral goodness‐of‐fit error (1‐GFC), and mean CIEDE2000 color difference (ΔE00) and by multiplying them together. After the optimal optic filter set was selected, it was applied to the Dunhuang murals spectral imaging and was evaluated. The results showed that the optimal optic filter set could result in promising improvement both in spectral and color accuracy when compared with the production camera. In addition, it can be used for the construction of Dunhuang murals spectral image database. © 2015 Wiley Periodicals, Inc. Col Res Appl, 41, 585–595, 2016
Phylogenetic ecology of gall crabs (Cryptochiridae) as associates of mushroom corals (Fungiidae)
Authors: van der Meij Sancia E. T. , Fransen Charles H. J. M. , Pasman Leon R. , Hoeksema Bert W. 
Published: November 2015

AbstractCoral‐associated fauna is a relatively understudied topic. Hence, the nature of the relationship between an associated organism and its host is usually unknown. In the present study, the obligate associations between gall crabs (Decapoda: Cryptochiridae) and mushroom corals (Scleractinia: Fungiidae) are reviewed from a phylogenetic perspective. Based on field surveys, examination of museum material and a literature review, a total of 35 fungiid species have been found that act as hosts for four gall crab species. Fungiid‐associated gall crabs appear to be more geographically widespread than previously known, with new records showing their occurrences from the Red Sea and western Indian Ocean all the way to the central Pacific Ocean. The obligate nature of the association between cryptochirids and their hosts makes them an ideal model taxon to test for possible cospeciation events. The congruence between their phylogenies was tested by using the program Jane 4.0, resulting in cospeciation and duplication events between the crabs and their host corals. The sharing of several closely related host coral species by the same gall crab species or genus may provide support to models indicating phylogenetic relationships within the Scleractinia.
Species mtDNAgenetic diversity explained by infrapopulation size in a host‐symbiont system
Authors: Doña Jorge , Moreno‐García Marina , Criscione Charles D. , Serrano David , Jovani Roger 
Published: November 2015

AbstractUnderstanding what shapes variation in genetic diversity among species remains a major challenge in evolutionary ecology, and it has been seldom studied in parasites and other host‐symbiont systems. Here, we studied mtDNAvariation in a host‐symbiont non‐model system: 418 individual feather mites from 17 feather mite species living on 17 different passerine bird species. We explored how a surrogate of census size, the median infrapopulation size (i.e., the median number of individual parasites per infected host individual), explains mtDNAgenetic diversity. Feather mite species genetic diversity was positively correlated with mean infrapopulation size, explaining 34% of the variation. As expected from the biology of feather mites, we found bottleneck signatures for most of the species studied but, in particular, three species presented extremely low mtDNAdiversity values given their infrapopulation size. Their star‐like haplotype networks (in contrast with more reticulated networks for the other species) suggested that their low genetic diversity was the consequence of severe bottlenecks or selective sweeps. Our study shows for the first time that mtDNAdiversity can be explained by infrapopulation sizes, and suggests that departures from this relationship could be informative of underlying ecological and evolutionary processes.
Circulating biomarker responses to medical management vs. mechanical circulatory support in severe inotrope‐dependent acute heart failure
Authors: Meredith Anna J. , Dai Darlene L. Y. , Chen Virginia , Hollander Zsuzsanna , Ng Raymond , Kaan Annemarie , Tebbutt Scott , Ramanathan Krishnan , Cheung Anson , McManus Bruce M. 
Published: November 2015

AbstractBackgroundSevere inotrope‐dependent acute heart failure (AHF) is associated with poor clinical outcomes. There are currently no well‐defined blood biomarkers of response to treatment that can guide management or identify recovery in this patient population. In the present study, we characterized the levels of novel and emerging circulating biomarkers of heart failure in patients with AHF over the first 30 days of medical management or mechanical circulatory support (MCS). We hypothesized a shared a plasma proteomic treatment response would be identifiable in both patient groups, representing reversal of the AHF phenotype.Methods and resultsTime course plasma samples of the first 30 days of therapy, obtained from patients managed medically (n = 8) or with implantable MCS (n = 5), underwent semi‐targeted and candidate biomarker analyses, using multiple reaction monitoring (MRM) mass spectrometry, antibody arrays, and enzyme‐linked immunosorbent assays. Differentially expressed proteins were identified using robust limma for MRM and antibody array data. Patients managed medically or with implantable MCS had a shared proteomic signature of six plasma proteins: circulating cardiotrophin 1, cardiac troponin T, clusterin, and dickopff 1 increased, while levels of C‐reactive protein and growth differentiation factor 15 decreased in both groups over the 30 day time course.ConclusionsWe have characterized the temporal proteomic signature of clinical recovery in AHF patients managed medically or with MCS, over the first 30 days of treatment. Changes in biomarker expression over the time course of treatment may provide a basis for understanding the biological basis of AHF, potentially identifying novel markers and pathophysiologic mechanisms of recovery.