bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of feasibility of 1.5 Tesla prostate MRI using body coil RF transmit in a patient with an implanted vagus nerve stimulator
Authors: Favazza Christopher P. , Edmonson Heidi A. , Ma Chi , Shu Yunhong , Felmlee Joel P. , Watson Robert E. , Gorny Krzysztof R. 
Published: September 2017

PurposeTo assess risks of RF‐heating of a vagus nerve stimulator (VNS) during 1.5 T prostate MRI using body coil transmit and to compare these risks with those associated with MRI head exams using a transmit/receive head coil.MethodsSpatial distributions of radio‐frequency (RF) B1 fields generated by transmit/receive (T/R) body and head coils were empirically assessed along the long axis of a 1.5 T MRI scanner bore. Measurements were obtained along the center axis of the scanner and laterally offset by 15 cm (body coil) and 7 cm (head coil). RF‐field measurements were supplemented with direct measurements of RF‐heating of 15 cm long copper wires affixed to and submerged in the “neck” region of the gelled saline‐filled (sodium chloride and polyacrylic acid) “head‐and‐torso” phantom. Temperature elevations at the lead tips were measured using fiber‐optic thermometers with the phantom positioned at systematically increased distances from the scanner isocenter.ResultsB1 field measurements demonstrated greater than 10 dB reduction in RF power at distances beyond 28 cm and 24 cm from isocenter for body and head coil, respectively. Moreover, RF power from body coil transmit at distances greater than 32 cm from isocenter was found to be lower than from the RF power from head coil transmit measured at locations adjacent to the coil array at its opening. Correspondingly, maximum temperature elevations at the tips of the copper wires decreased with increasing distance from isocenter — from 7.4°C at 0 cm to no appreciable heating at locations beyond 40 cm.ConclusionsFor the particular scanner model evaluated in this study, positioning an implanted VNS farther than 32 cm from isocenter (configuration achievable for prostate exams) can reduce risks of RF‐heating resulting from the body coil transmit to those associated with using a T/R head coil.
THE BOUNDED APPROXIMATION PROPERTY FOR THE WEIGHTED SPACES OF HOLOMORPHIC MAPPINGS ON BANACH SPACES
Authors: GUPTA MANJUL , BAWEJA DEEPIKA 
Published: September 2017

AbstractIn this paper, we study the bounded approximation property for the weighted space$\mathcal{HV}$(U) of holomorphic mappings defined on a balanced open subsetUof a Banach spaceEand its predual$\mathcal{GV}$(U), where$\mathcal{V}$is a countable family of weights. After obtaining an$\mathcal{S}$-absolute decomposition for the space$\mathcal{GV}$(U), we show thatEhas the bounded approximation property if and only if$\mathcal{GV}$(U) has. In case$\mathcal{V}$consists of a single weightv, an analogous characterization for the metric approximation property for a Banach spaceEhas been obtained in terms of the metric approximation property for the space$\mathcal{G}_v$(U).
Die infizierte Spondylodese
Authors: Zwingenberger Stefan , Schaser Klaus-Dieter , Stiehler Maik , Bernstein Peter , Thürmer Alexander , Disch Alexander 
Published: September 2017

ZusammenfassungDie implantatassoziierte Infektion ist eine der häufigsten Komplikationen nach operativer Spondylodese. Die klinische Symptomatik kann akut fulminant, protrahiert oder auch atypisch verlaufen. Frühinfekte entstehen in der Regel durch den operativen Eingriff selbst, Spätinfekte sind dagegen meistens von hämatogener Genese. Die antibiotische Behandlung sollte erst nach mikrobiologischer Diagnostik begonnen werden. Das Entnehmen von mindestens 5 Biopsaten im antibiotikafreien Intervall (> 48 h) sowie das Einsenden der Implantate zur Sonikation erhöhen signifikant die Keimnachweiswahrscheinlichkeit. Durch Einsenden von Gewebeproben zur histopathologischen Untersuchung können mikrobiologische Kontaminationen von echten Infektionen unterschieden werden. Bei Vorliegen eines akuten Infekts ist eine einmalige implantaterhaltende Revision möglich. Infektbedingte, knöcherne Destruktionen sowie Gewebsnekrosen sollten radikal debridiert, gelockerte Implantate entfernt oder gewechselt werden. Postoperativ sollte mit einer empirischen, die häufigsten Erreger abdeckenden, Antibiose begonnen werden, die im Verlauf ggf. gemäß Resistogramm angepasst werden sollte. Das Behandlungskonzept sollte interdisziplinär mit mikrobiolgischer und infektiologischer Expertise erfolgen.
Antibiotic Stewardship in Orthopädie und Unfallchirurgie
Authors: Horn Dagmar , Köck Robin , Wähnert Dirk , Roßlenbroich Steffen , Raschke Michael 
Published: September 2017

ZusammenfassungIn Zeiten steigender Antibiotikaresistenzen wird der rationale Umgang mit Antiinfektiva immer wichtiger. „Antibiotic Stewardship“ (ABS) ist ein Konzept, bei dem versucht wird, in interdisziplinärer Zusammenarbeit von Chirurgen, Infektiologen, Apothekern und Mikrobiologen das Antibiotikamanagement, die Aspekte der Diagnostik und Infektionsprävention zu optimieren.
Gesundheitsreport berufstätig Studierender: Analyse zur Gesundheitsförderung in Studium und Beruf, Zahlungsbereitschaft
und Nutzung digitaler Medien
Authors: Matusiewicz David , Krol B. , Stender T. , Lux G. 
Published: September 2017

Zusammenfassung
Hintergrund Das Gesundheitsverhalten von Studierenden in Deutschland ist insgesamt bislang wenig empirisch untersucht worden. Die
vorliegende Analyse hat den Fokus auf berufstätige Studierende in Deutschland gelegt, da diese Zielgruppe einer Doppelbelastung ausgesetzt
ist. Die Zahl der berufstätig Studierenden in Deutschland steigt zunehmend an, sodass die besondere Situation der doppelten Belastung aus
Studium und Beruf einer Untersuchung bedarf. Die vorliegende Studie untersucht die Förderung der Gesundheit in Studium und Beruf, die
Zahlungsbereitschaft und Nutzung digitaler Medien.
Methodik Die Methodik beruht auf einer Online-Befragung (LimeSurvey) von n = 1028 Studierenden im März 2016 an der FOM Hochschule.
Ziel der Studie war es, einen Überblick über das Gesundheitsverhalten von berufstätigen Studierenden aufzuzeigen. Es wurden
wissenschaftliche Erkenntnisse über die Zahlungsbereitschaft für Gesundheitsleistungen und die Nutzung von digitalen Medien erhoben. Die
statistischen Auswertungen (t-test, ANOVA, Konfidenzintervalle) wurden mit SPSS in der Version 21 durchgeführt.
Ergebnisse Der Rückhalt in der Familie war mit 83,5 % der am häufigsten genannte Grund für Gesundheit und allgemeines Wohlbefinden. Es
folgten die Pflege sozialer Kontakte mit 81,4 %, die gesunde Ernährung mit 77,8 % und knapp dahinter die Work-Life-Balance mit 77,6 %. Eine
ausreichende Zeit für Hobbies und Freizeit war für den Großteil der Studierenden ebenso wichtig (74,3 %). Weiter sind der Erfolg im Beruf
(73,8 %) sowie der regelmäßige Sport (65,7 %) als wichtig bewertet worden. Der Mittelwertvergleich der unterschiedlichen Berufsgruppen
bezüglich der Fehltage zeigte auf, dass die Fehltage bei der Berufsgruppe der Beamten (12,7; 95 %-KI: 0,3–25,1) durchschnittlich etwa
doppelt so hoch gewesen sind, wie bei Angestellten (6,3; 95 % KI: 5,7–6,9). Die Unterschiede nach Berufsgruppen sind statistisch signifikant
(p = 0,035). Die meisten privaten Ausgaben sind in den Bereichen Ernährung und Sport investiert worden. Dabei gaben die Studierenden für die
genannten Bereiche durchschnittlich rund 63,8 Euro pro Monat aus. Die Ergebnisse der vorliegenden Primärdatenerhebung haben gezeigt, dass
die Studierenden durchschnittlich 1,8 Stunden pro Woche (SD 2,8) zur Informationssuche zum Thema Gesundheit verbracht haben. Hierzu zählten
auch Themen zur Gesundheitsförderung (Ernährung, Sport und Bewegung). Das Vertrauen in die Online-Informationen verschiedener Akteure wurde
unterschiedlich bewertet.
Diskussion und Fazit Berufstätige Studierende stehen vor besonderen Herausforderungen, die die Gesundheit und das Wohlbefinden
beeinflussen. Insgesamt ist das Thema Gesundheit ein durchaus wichtiges Thema und die Studierenden sind bereit, dafür Zeit und Geld zu
investieren und nutzen ebenso digitale Medien, wobei auch Herausforderungen bestehen, die richtigen Informationen zu finden.
Mucosal Cytokine Profiles After Induction Therapy With Granulocyte/Monocyte Apheresis in New‐onset Inflammatory Colitis
Authors: Rolandsdotter Helena , Jönsson‐Videsäter Kerstin , L. Fagerberg Ulrika , Eberhardson Michael , Finkel Yigael 
Published: September 2017

ABSTRACTGranulocyte/monocyte apheresis (GMA) selectively removes circulating granulocytes and monocytes; important producers of proinflammatory cytokines. Seven children with new‐onset inflammatory bowel disease (IBD) colitis were treated with GMA together with mesalazine, and had significant decreases in Pediatric UC Activity Index (P = 0.018) and Mayo endoscopic score (P = 0.013). We investigated the colonic mucosal cytokine profiles (analyzed with real‐time polymerase chain reaction), before and after induction treatment, and in 6 non‐IBD controls. Significant decreases were seen in Colony Stimulating Factor 2 (P = 0.018), tumor necrosis factor‐α (P = 0.028), interleukin (IL)‐23α (P = 0.043), IL‐1β (P = 0.028), IL‐36γ (P = 0.018), IL‐10 (P = 0.028), and transforming growth factor beta 1 (P = 0.043) after treatment. In 6 non‐IBD controls there were significantly lower levels of IL‐12β (P = 0.023) and IL‐23α (P = 0.046) compared to the patients with IBD at onset, and IL‐22 (P = 0.088) and IL‐36γ (P = 0.062) showed lower values without reaching significant differences. We speculate that the decreases in colonic mucosal cytokine profiles after treatment may explain the observed clinical efficacy in the GMA‐treated children with IBD.
Diplopia: An Overlooked Feature in Patients With Neurosyphilis. Report of 2 Cases and Literature Review
Authors: Rolimpandoei Sarah Patricia , Sun Xiaodong , Shi Xin , Leman Ryan Edrick , Xie Lixia , Chen Lingling 
Published: September 2017

Abstract
Both neurosyphilis and diplopia are widely known medical terms. Nevertheless, low clinical awareness by the physician and the often-overlooked presentation of diplopia, make the combination of neurosyphilis and diplopia rarely observed. In this article, we report 2 neurosyphilitic patients presenting with diplopia and review 8 additional case reports of neurosyphilis with diplopia, with a total of 10 cases to be analyzed.
Factors Influencing Successful Lumbar Puncture in Alzheimer Research
Authors: Moulder Krista L. , Besser Lilah M. , Beekly Duane , Blennow Kaj , Kukull Walter , Morris John C. 
Published: September 2017

Objective:
Lumbar puncture (LP) is increasingly common in Alzheimer disease research; however, agreement to undergo LP varies. We sought to determine factors influencing LP consent at Alzheimer’s Disease Centers (ADCs) in the United States.

Methods:
A 3-part survey was distributed to each ADC: (1) ADC LP Experience; (2) LP Requestor Experience; and (3) Patient LP Experience (both Initial and Follow-up). In all, 64 LP Requestor, 579 Patient/Initial, and 404 Patient/Follow-up surveys were collected. Logistic regression analyses with generalized estimating equations were used to assess factors associated with LP agreement and post-LP complications.

Results:
Asians and those viewing LP negatively were less likely to agree to LP. Three hundred fifty-two participants had an LP; LP headache occurred in 11.9% (blood patch required in 1.4%) and 9.9% reported other complications. Younger individuals, women, those diagnosed with mild cognitive impairment, use of a Quincke needle, ≤20 mL cerebrospinal fluid drawn, and hemorrhage during LP were associated with LP headache. Use of gravity flow during LP was associated with fewer other complications (nausea, dizziness, vasovagal response, back pain, neck stiffness, and/or nerve root pain).

Conclusions:
LP in Alzheimer disease research is generally safe and well tolerated. Factors influencing LP agreement potentially could be studied to advance participant acceptance of the procedure.
Letter: the importance of dosing and baseline haemoglobin when establishing the relative efficacy of intravenous iron therapies
Authors: Reinisch W. , Lindgren S. 
Published: September 2017

Linked ContentThis article is linked to Aksan et al papers. To view these articles visit https://doi.org/10.1111/apt.14269 and https://doi.org/10.1111/apt.14043.
Case report of perineal hernia after laparoscopic abdominoperineal resection
Authors: Honjo Kumpei , Sakamoto Kazuhiro , Motegi Shunsuke , Tsukamoto Ryoichi , Munakata Shinya , Sugimoto Kiichi , Kamiyama Hirohiko , Takahashi Makoto , Kojima Yutaka , Fukunaga Tetsu , Kajiyama Yoshiaki , Kawasaki Seiji 
Published: September 2017

AbstractPerineal hernia (PH) is a rare complication following laparoscopic abdominoperineal resection (APR) for rectal cancer. We present a case report of perineal hernia after laparoscopic APR and discuss its management. The patient was a 77‐year‐old man who was diagnosed with lower rectal cancer. He underwent laparoscopic APR and bilateral lateral lymph node dissection. Two months after the surgery, pain and bulging in the perineal region developed, and PH was diagnosed by CT. Repair with a polypropylene mesh was performed using a combination of laparoscopic abdominal and transperineal approaches. Reportedly, the incidence of secondary PH after APR has increased along with the rate of laparoscopic surgery. Treatment of secondary PH with transperineal repair alone may cause injuries to other organs because of adhesion of the pelvic viscera. In the present case, we safely repaired the hernia repair using a laparoscopy‐assisted perineal approach.
The RaDiCo AC‐OEIL : a French rare disease cohort dedicated to ocular developmental anomalies in children
Authors: CALVAS P. , Jamot L. , Weinbach J. , Chassaing N. , RaDiCo Team T. ,   O.B.O. Sensgene, AnDDi‐rare Networks
Published: September 2017

PurposeOcular development may be disrupted at various stages, leading to a wide range of congenital ocular dysgenesis. Incidence of such defects is estimated to 1‐2 in 10.000. They may be isolated or associated with extra‐ocular malformations. In addition, psychomotor delay may be present, secondary to the sensory involvement or linked to a cerebral developmental anomaly leading to intellectual disability. Visual outcome, frequency of extra‐ocular features and psychomotor delay are still poorly known. Given the rarity of these malformations, available data concern very heterogeneous groups of patients, which make their utility limited in clinical practice. It is thus difficult to anticipate visual and neurologic outcomes when a congenital ocular developmental anomaly is diagnosed.MethodsRaDiCo‐AC‐ŒIL is an observational study launched in May 2017 sponsored by Inserm, relying on the French Rare Diseases healthcare networks SENSGENE and ANDDI‐Rare for patients’ enrolment, and supported by patients ‘associations. Patients will have a maximum of three clinical examinations (at time of diagnosis, at 5‐7‐year‐old, and at 9‐11‐year‐old) during which visual, neuro‐developmental and quality‐of‐life data will be collected in addition to the usual clinical data, using REDCap EDC system. It will extend to other EU countries once regulatory requirements will be fulfilled.ResultsAbout 800 patients are expected to be enrolled during a recruitment period of 10 years. ConclusionsRaDiCo‐AC‐ŒIL will improve i) our knowledge on the natural history of ocular developmental defects in children ii) the identification of prognostic factors for ocular and neurodevelopmental outcome iii) genetics counselling and iv) the design of optimised management protocols. This project will also pave the way to clinical and basic research in a homogeneous cohort.
Vascular macular capillary plexus in patient with Type 1 diabetes with no retinopathy are correlated with OCT volume changes
Authors:   E. ORDUNA HOSPITAL, Lopez Galvez M.I. , Perdices Royo L. , Acha J. , Idoipe M. , Sanchez‐Cano A.I. , Abecia E. , Pinilla I. 
Published: September 2017

PurposeDiabetic retina undergoes neurodegenerative changes at the neuronal level in addition to vascular changes. Neuronal changes can be study indirectly using spectral domain OCT thickness and volumen. OCT angiography (OCTA) allows studying the macular vascular plexus in a non‐invasive way. The purpose of our study was to evaluate changes in the macular vascular density changes using OCTA, and to examine its correlation with OCT macular thickness diminution over 8 year follow‐up in patients with type 1 diabetes and no signs of diabetic retinopathy. To quantify foveal avascular zona (FAZ) area and to correlate with vascular modifications.Methods18 eyes of 9 diabetic patients with no retinopathy were studied by SD‐OCT at 2009. The patients were reexamined by SD‐OCT looking for changes in macular thickness and volumen; all eyes underwent angio OCT. FAZ was manually measured. Macular thickness and volume changes over these 8 years were correlated with finding at the OCTA and FAZ area.ResultsMean age of the patients was 35.32±14.23 years (range 23‐54). Mean time of diabetes evolution was 15.96±11.46 years. Best corrected visual acuity (BCVA) was between 0 and ‐0.3 logMAR. 16 eyes showed no signs of diabetic retinopathy. One patient had mild‐moderate diabetic retinopathy with macular edema in his LE. Eyes with OCTA changes showed modification in both superficial and deep plexus. Vascular changes included reduced capillary density, regions of capillary dropout and foveal avascular enlargement. Patients with OCTA changes displayed a diminished macular volume over the 8 years of follow up (excluding the one with diabetic retinopathy).ConclusionsDespite we are not able to find signs of diabetic retinopathy, type 1 diabetic patients develop changes at the vascular level that are related to a diminution of the OCT macular volume.
Changes in visual function and retinal structure in patients with manic‐depressive illness or bipolar disorder
Authors:   E. ORDUNA HOSPITAL, Vilades Palomar E. , Cipres M. , Obis J. , Rodrigo M.J. , Satue M. , Garcia‐Martin E. 
Published: September 2017

PurposeTo evaluate changes in visual function and changes in the macula and in the retinal nerve fiber layer (RNFL) measured by spectral domain optical coherence tomography (SD‐OCT) in patients with Bipolar Disorder.Methods30 eyes of 15 patients with Bipolar Disorder and 72 eyes of 36 healthy subjects were analyzed. All of them were evaluated for the best corrected visual acuity (VA) using the 100%, 2.5% and 1.25% saturation ETDRS test. The contrast sensitivity was evaluated with the Pelli Robson test and the CSV1000E test. The color vision was evaluated with the Farnsworth and Lanthony D15 tests. All participants were assessed with the SD‐OCT to obtain macular thickness and retinal nerve fiber layer (RNFL) measurements.ResultsThe patients with Bipolar Disorder presented lower VA in low contrasts (2.50% and 1.25%, p < 0.05). Significant differences in color vision were also found with the Lanthony Test in the AC CCi, CIndex and CCI indices (p < 0.05). There were no significant differences in contrast sensitivity with Pelli Robson or CSV1000E nor in the vision of color with the Farnsworth test. In the RNFL a significant thinning was observed in the temporal areas of the optic nerve (temporal, temporal superior and temporal inferior, p < 0.05) in patients with Bipolar Disorder compared to healthy patients. No differences were observed at the macular area.ConclusionsPatients with Bipolar Disorder present alterations in the visual function as well as axonal loss measured by optical coherence tomography.
Reproducibility of the measurements taken with swept source optical coherence tomography
Authors:   E. ORDUNA HOSPITAL, Vilades Palomar E. , Cipres M. , Obis J. , Rodrigo M.J. , Satue M. , Garcia‐Martin E. 
Published: September 2017

PurposeTo evaluate the measurements reproducibility of the macular area and of the retinal nerve fiber layer (RNFL) taken with different protocols with swept source optical coherence toography (SS‐OCT) Triton.Methods108 eyes from 108 healthy subjects were included whose macular thickness and RFNL thickness were analyzed by SS‐OCT Triton (Topcon, Japan). To study the reproducibility of the device, three measurements were taken followed by different protocols: 3D (H) + 5LineCross and 3D Macular (H) protocols (macular thickness) and 3D Disc protocol (RNFL and optic nerve morphometric values). The coefficients of variation (COV) and intraclass coefficients (ICC) were calculated.ResultsA high reproducibility was obtained with mean COV by type of protocol used of 8.31 ± 13.54% to 1 ± 1, 6% being the less reproducible protocol for the measurement of RNFL 8.31 ± 13.54%. The macular area data in all ETDRS quadrants (11.6% to 37%) were more accurate than those of RNFL (2% macular vs 8% RNFL). The ICC of the optic nerve morphometric values presented a range of 0.91 to 0.53, being the vertical diameter disk value the less accurate. The ICC values of the total macular thickness were the most accurate (0.963 to 0.839). Little variability was observed in the RNFL thickness (ICC 0.946 to 0.750).ConclusionsThere is a high reproducibility of the protocols performed with Triton OCT. The total value of the RNFL protocol is much more variable than the macular protocols, being the temporal quadrants less reproducible than the nasal ones. These results could influence negatively in the evaluation of patients with neurodenegerative diseases where the most affected area is the temporal one.
Assessment of Instructions on Protection Against Food Contaminated with Radiocesium in Japan in 2011
Authors: Seto Mayumi , Uriu Koichiro , Kawaguchi Isao , Yokomizo Hiroyuki 
Published: September 2017

AbstractThe Japan Ministry of Health, Labour and Welfare (MHLW) has published instructions for radiological protection against food after the Fukushima Daiichi nuclear power plant accident in 2011. Following the instructions, the export and consumption of food items identified as being contaminated were restricted for a certain period. We assessed the validity of the imposed restriction periods for two representative vegetables (spinach and cabbage) grown in Fukushima Prefecture from two perspectives: effectiveness for reducing dietary dose and economic efficiency. To assess effectiveness, we estimated the restriction period required to maintain consumers’ dose below the guidance dose levels. To assess economic efficiency, we estimated the restriction period that maximizes the net benefit to taxpayers. All estimated restriction periods were shorter than the actual restriction periods imposed on spinach and cabbage from Fukushima in 2011, which indicates that the food restriction effectively maintained consumers’ dietary dose below the guidance dose level, but in an economically inefficient manner. We also evaluated the response of the restriction period to the sample size for each weekly food safety test and the instructions for when to remove the restriction. Stringent MHLW instructions seemed to sufficiently reduce consumers’ health risk even when the sample size for the weekly food safety test was small, but tended to increase the economic cost to taxpayers.