bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of age at diagnosis on disease progression in patients with primary sclerosing cholangitis
Authors: Rupp Christian , Rössler Alexander , Zhou Taotao , Rauber Conrad , Friedrich Kilian , Wannhoff Andreas , Weiss Karl‐Heinz , Sauer Peter , Schirmacher Peter , Süsal Caner , Stremmel Wolfgang , Gotthardt Daniel N 
Published: June 2017

BackgroundThe median age of diagnosis of primary sclerosing cholangitis (PSC) is ∼30–40 years.ObjectiveWe aimed to analyse disease progression and liver‐dependent survival in patients diagnosed with PSC after 50 years of age.MethodsPatients with PSC were analysed with regard to their age at diagnosis. Patients with a first diagnosis of PSC after the age of 50 years were considered as the late‐onset group.ResultsA total of 32/215 (14.9%) patients were diagnosed with PSC after 50 years of age. The proportion of females was significantly higher among patients with late‐onset PSC (48.4 vs. 27.3%; p  = 0.02). Patients with later diagnosis required dilatation therapy more often due to dominant stenosis (84.2 vs. 53.1%; p  = 0.01) and suffered from recurrent cholangitis more often (48.3 vs. 21.0%; p  = 0.003). Patients with late‐onset PSC had reduced transplantation‐free survival (10.5 ± 0.6 years vs. 20.8 ± 1.7 years, p  < 0.0001), with progredient liver failure and cholangiocarcinoma as the leading causes of death.ConclusionsPatients with later age at diagnosis of PSC displayed a different clinical phenotype with a different sex ratio, immune status and an increased risk for progressive liver failure and biliary malignancies.
The stability of the rare sodium antimonate, brizziite, and it's role in Sb mobility
Authors: Roper Adam J. , Leverett Peter , Murphy Timothy D. , Williams Peter A. 
Published: June 2017

ABSTRACTSynthesis and solubility studies of brizziite, NaSbO3, have been undertaken to determine the possible role of this rare secondary phase in the immobilization of Sb under supergene conditions and the conditions responsible for its formation in the supergene zone. Solubility studies were undertaken atT= 298.15 K. A value of ΔGfө) (NaSbO3, s, 298.15 K) = –806.66 ± 1.4 kJ mol–1was derived. Calculations involving tripuhyite, FeSbO4, byströmite, MgSb2O6, ordoñezite, ZnSb2O6and rosiaite, PbSb2O6, show that brizziite is a thermodynamically stable phase only at negligible activities of Pb2+(aq) at high pH and high salinity. Calculations involving mopungite Na[Sb(OH)6] combined with reported mineral associations suggest that mopungite is the thermodynamically unstable precursor to brizziite and its presence in natural settings must be due to kinetic stability. This explains why brizziite is such a rare secondary phase and therefore why it cannot exert any significant influence on the dispersion of Sb in the supergene environment.
Deposition conditions for the indium-bearing polymetallic quartz veins at Sarvlaxviken, south-eastern Finland
Authors: Broman C. , Sundblad K. , Valkama M. , Villar A. 
Published: June 2017

ABSTRACTPolymetallic quartz veins, with up to 1500 ppm indium, have been discovered recently in the Sarvlaxviken area within the 1.64 Ga anorogenic multiphase Wiborg rapakivi batholith and adjacent 1.90 Ga Svecofennian crust in SE Finland. Evidence from primary fluid inclusions in the Sarvlaxviken area provides new information on the hydrothermal transport and depositional processes of metals in anorogenic granites. Fluid inclusions with variable aqueous liquid and vapour proportions (5–90 vol.% vapour) occur in quartz, cassiterite and fluorite belonging to three generations of polymetallic quartz veins. Microthermometry indicates that the veins were deposited at temperatures that range from ~500°C down to <100°C and salinities from 0 to 16 eq. mass% NaCl. Fluid inclusion data show that the depositional conditions were similar regardless of vein generation. The interpreted depositional processes involve phase separation with a combination of condensation, cooling and boiling of an initially low-salinity (<3 eq. mass% NaCl) aqueous magmatic vapour phase enriched in CO2-F-Cl-S and metals. Fluid inclusions with low salinities dominate, but higher salinities are recorded in metal-rich parts of the veins. The turbulent fluid flow, with complex geometry and temperature-salinity patterns, may explain why sulfide and/or oxide opaque minerals occur irregularly, and are locally the dominating vein minerals, but disappear completely into barren parts of the quartz veins. All fluids are considered to have been generated by the F-rich Marviken granite (and related granite dykes), which show all geochemical criteria for an ore-fertile granite. The quartz veins investigated in the adjacent Svecofennian country rocks are considered to represent the very last stage of a fluid with similar characteristics to the fluid responsible for the ore formation in the Sarvlaxviken area, but that had cooled to <100°C.
Best proximity points for proximal contractive type mappings with C-class functions in S-metric spaces
Authors: Ansari Arslan Hojat , Nantadilok Jamnian 
Published: June 2017

AbstractIn this paper, we use the concept of C-class functions to establish the best proximity point results for a certain class of proximal contractive mappings in S-metric spaces. Our results extend and improve some known results in the literature. We give examples to analyze and support our main results.
Biofluid lipidome: a source for potential diagnostic biomarkers
Authors: Ghosh Arkasubhra , Nishtala Krishnatej 
Published: June 2017

AbstractLipidomics is the identification and quantitation of changes in the lipidome of a cell, tissue, organ or biofluid in health and disease using high resolution mass spectrometry. Lipidome of a particular organism has relevance to the disease manifestation as it reflects the metabolic changes which can be a consequence of the disease. Hence these changes in the molecules can be considered as potential markers for screening and early detection of the disease. Biological fluids as blood/serum/plasma, urine, saliva, tear and cerebrospinal fluid, due to their accessibility, offer ease of collection with minimal or no discomfort to the patient and provide a ready footprint of the metabolic changes occurring during disease. This review provides a brief introduction to lipidomics and its role in understanding the metabolic changes in health and disease followed by discussion on the chemical diversity of the lipid species and their biological role, mammalian lipids and their metabolism and role of lipids in pathogens and the immune response before dwelling further into importance of studying lipidome in various biological fluids. The challenges in performing a lipidomic analysis at the experimental and data analysis stages are discussed.
Assessing explanatory models and health beliefs: An essential but overlooked competency for clinicians
Authors: Dinos Sokratis , Ascoli Micol , Owiti John A. , Bhui Kamaldeep 
Published: June 2017

SummaryExplanatory models of illness – the way people perceive, interpret and respond to it – are mediated not only by the illness itself, but also by cultural and social contexts. This article discusses recent evidence showing how the exploration of explanatory models can help to shape treatment and outcomes for some of the most common categories of mental illness, and presents case studies illustrating dilemmas clinicians face when their explanatory models differ from those of their patients. It concludes with recommendations on how a culturally sensitive clinical approach based on the exploration of explanatory models during assessment and treatment can be used as an effective way of dealing with the complexity of patients' and families' needs.Learning Objectives• Appreciate the use of explanatory models in clinical practice• Understand the relevance of explanatory models in relation to specific diagnostic categories of mental illness• Recognise that dilemmas may arise if the explanatory models of the clinician and the patient differ, and be able to manage this tension
Parity of esteem: Addressing the inequalities between mental and physical healthcare
Authors: Mitchell Alex J. , Hardy Sheila , Shiers David 
Published: June 2017

SummaryParity of esteem means valuing mental health as much as physical health in order to close inequalities in mortality, morbidity or delivery of care. There is clear evidence that patients with mental illness receive inferior medical, surgical and preventive care. This further exacerbated by low help-seeking, high stigma, medication side-effects and relatively low resources in mental healthcare. As a result, patients with severe mental illness die 10–20 years prematurely and have a high rate of cardiometabolic complications and other physical illnesses. Many physical healthcare guidelines and policy recommendations address parity of esteem, but their implementation to date has been poor. All clinicians should be aware that inequalities in care are adversely influencing mental health outcomes, and managers, healthcare organisations and politicians should provide resources and education to address this gap.Learning Objectives• Understand the concept of parity of esteem• Be aware of the current inequalities in mental healthcare• Appreciate how parity of esteem may be improved
Clinical formulation: Where it came from, what it is and why it matters
Authors: Baird John , Hyslop Alan , Macfie Marjorie , Stocks Ruth , Van der Kleij Tessa 
Published: June 2017

SummaryClinical formulation was introduced in its present form a little over 30 years ago and is, in essence, a concise summary of the origins and nature of a person's problems, together with opinion on what may go wrong in the future and what steps should be taken to improve matters. In our article we discuss how, in recent times, the task of preparing a clinical formulation has rightly become a multidisciplinary exercise involving the whole clinical team and, even more important, that nowadays the patient – the subject of the clinical formulation – together with their carers should also be actively involved in the process and feel some ownership of the conclusions and decisions. In addition, we compare these developments in clinical formulation with similar developments, arising for the same reasons, in clinical teaching and education.Learning Objectives• Understand the core principles of formulation• Know how to prepare a formulation within a clinical team• Understand the role that formulation plays in the effective management of patients
Malingering mental disorders: Medicolegal reporting
Authors: Rix Keith J. B. , Tracy Derek K. 
Published: June 2017

SummaryIn this second part of a two-article review on malingering we consider the challenges of presenting clinical and psychometric findings. Numerous clinical and demographic factors are statistically associated with malingering but applying them to an individual case risks challenges to the expert psychiatric witness's evidence. Although psychometric data can usefully help strengthen or challenge a diagnosis, expert witnesses must recognise and report the limitations of these tests. We recommend that psychiatric expert witnesses do not try to look for or to link any external incentives with clinical findings, and indeed we suggest that they should, other than exceptionally, avoid using the term ‘malingering’. It is the job of the court, not the expert witness, to ascertain an individual's credibility and motives. We suggest a framework for presenting expert psychiatric evidence in this area.Learning Objectives• Appreciate clinical and sociodemographic factors associated with malingering, and the challenges to applying these in individual cases• Understand the legal scrutiny to which the reporting of psychometric data might be exposed• Appreciate the roles of the expert witness and the court, and have a suitable framework for reporting expert psychiatric evidence in such cases
Platelet Counts and Postoperative Stroke After Coronary Artery Bypass Grafting Surgery
Authors: Karhausen Jörn A. , Smeltz Alan M. , Akushevich Igor , Cooter Mary , Podgoreanu Mihai V. , Stafford-Smith Mark , Martinelli Susan M. , Fontes Manuel L. , Kertai Miklos D. 
Published: June 2017

BACKGROUND:Declining platelet counts may reveal platelet activation and aggregation in a postoperative prothrombotic state. Therefore, we hypothesized that nadir platelet counts after on-pump coronary artery bypass grafting (CABG) surgery are associated with stroke.METHODS:We evaluated 6130 adult CABG surgery patients. Postoperative platelet counts were evaluated as continuous and categorical (mild versus moderate to severe) predictors of stroke. Extended Cox proportional hazard regression analysis with a time-varying covariate for daily minimum postoperative platelet count assessed the association of day-to-day variations in postoperative platelet count with time to stroke. Competing risks proportional hazard regression models examined associations between day-to-day variations in postoperative platelet counts with timing of stroke (early: 0–1 days; delayed: ≥2 days).RESULTS:Median (interquartile range) postoperative nadir platelet counts were 123.0 (98.0–155.0) × 109/L. The incidences of postoperative stroke were 1.09%, 1.50%, and 3.02% for platelet counts >150 × 109/L, 100 to 150 × 109/L, and <100 × 109/L, respectively. The risk for stroke increased by 12% on a given postoperative day for every 30 × 109/L decrease in platelet counts (adjusted hazard ratio [HR], 1.12; 95% confidence interval [CI], 1.01–1.24;P= .0255). On a given day, patients with moderate to severe thrombocytopenia were almost twice as likely to develop stroke (adjusted HR, 1.89; 95% CI, 1.13–3.16;P= .0155) as patients with nadir platelet counts >150 × 109/L. Importantly, such thrombocytopenia, defined as a time-varying covariate, was significantly associated with delayed (≥2 days after surgery; adjusted HR, 2.83; 95% CI, 1.48–5.41;P= .0017) but not early postoperative stroke.CONCLUSIONS:Our findings suggest an independent association between moderate to severe postoperative thrombocytopenia and postoperative stroke, and timing of stroke after CABG surgery.
Você tem fome de quê? Uma reflexão sobre patrimônio, legitimidade e novas perspectivas analíticas
Authors: Souza Luciana Christina Cruz 
Published: June 2017

Partindo de uma provocação sore o universo simbólico e a necessidade de considerá-lo como elemento primordial à vida humana, o presente artigo trata sobre o patrimônio e as escolhas, os juízos, que envolvem a seleção e a preservação de bens culturais. Recorre, portanto, à importância atribuída à figura do técnico-especialista no trato com o patrimônio, seja na esfera do Estado ou no museu, enquanto agente que parece reunir a capacidade/legitimidade de nomear e tratar o patrimônio. Partindo do pressuposto que há uma concentração de agentes provenientes de específicas disciplinas que se revelam responsáveis, ou se consideram exclusivamente aptos, à condução da seleção de bens culturais e das práticas de preservação desses bens, o artigo, em formato de ensaio de natureza teórica, reflete sobre as relações de colonialidade que parecem atravessar as dinâmicas do campo do patrimônio a partir da figura dos técnicos-especialistas. Palavras-chave: Patrimônio, Preservação, Colonialidade.
A museologia social na prática comunitária: o caso da Casa da Memória Viva de Ceilândia, DF
Authors: Pereira Vinicius Carvalho 
Published: June 2017

O artigo apresenta as ações desenvolvidas pela Casa da Memória Viva de Ceilândia junto à comunidade escolar, desta que é a mais populosa região administrativa do Distrito Federal. As atividades têm como foco a valorização da cultura e história locais, e principalmente da memória dos candangos, trabalhadores que participaram da construção de Brasília, que por vezes são deixadas de lado pela história oficial. Este museu comunitário os define como memória viva, que seriam pessoas portadoras de uma memória coletiva. Por meio de entrevistas com os colaboradores da instituição e a revisão bibliográfica especialmente da Nova Museologia, procuramos mostrar como esse museu desenvolveu desde a sua fundação trabalhos em conjunto com a comunidade local. Palavras-chave: Patrimônio, Memória, Ceilândia-DF, Candangos, Museologia
Schizophrenia and sense of coherence
Authors: Witkowska-Łuć Bogumiła 
Published: June 2017

Cel pracyCelem prezentowanych badań było poznanie zależności między poziomem poczucia koherencji (SOC) a poprawą objawową, rozumianą jako wskaźnik zdrowienia u pacjentów z zaburzeniami z kręgu schizofrenii.MetodaGrupę badaną stanowiło 134 pacjentów z diagnozą schizofrenii paranoidalnej (118 osób) lub zaburzeń schizoafektywnych (16 osób) leczonych w psychiatrycznych oddziałach całodobowych. Średni wiek osób badanych wynosił 36,22 lata (SD=8,51). Do oceny poczucia koherencji zastosowano Kwestionariusz Orientacji Życiowej A. Antonovsky. Poziom nasilenia objawów psychopatologicznych zbadano dwukrotnie na początku i na końcu hospitalizacji za pomocą Skali Objawów Pozytywnych i Negatywnych (PANSS). Wskaźnikiem zdrowienia hospitalizowanego pacjenta była różnica w nasileniu objawów psychopatologicznych podczas rozpoczynania oraz kończenia leczenia szpitalnego.WynikiZ przeprowadzonych analiz wynika, że wyższemu poczuciu zrozumiałości (SOCCOM) sprzyja mniejsze nasilenie objawów negatywnych oraz ogólnej symptomatologii psychiatrycznej w PANSS podczas rozpoczynania hospitalizacji badanych pacjentów. Również osoby charakteryzujące się istotnie wyższym poczuciem koherencji ogólnej (SOC) prezentują wyraźnie mniejsze nasilenie objawów negatywnych podczas przyjęcia do szpitala. Wyniki badań pokazały, że wyższy poziom ogólnej koherencji (SOC) oraz wyższe poczucie zrozumienia (SOCCOM) współwystępują z mniejszą różnicą w zakresie nasilenia objawów psychopatologicznych.WnioskiNiniejszy artykuł stara się odpowiedzieć na ważne pytanie dotyczące roli poczucia koherencji w procesie zdrowienia pacjentów z zaburzeniami z kręgu schizofrenii. Sugeruje się, że współwystępowanie wyższego poczucia koherencji z większymi objawami negatywnymi oraz ogólnymi objawami psychopatologicznymi może stanowić u pacjentów kończących hospitalizację psychiatryczną przejaw osiąganego przez nich wglądu w chorobę, co można uznać za przejaw zdrowienia.
Ambivalent apocalypse: The influence of the Book of Revelation in films and television
Authors: Baker Sarah 
Published: June 2017

Abstract
Apocalyptic texts are a popular genre of film and television that commonly present humanity as decimated, or threatened by decimation. Zombie apocalyptic themes have become popular and are seen in 28 Days later (Boyle, 2002), I am Legend (Lawrence, 2008), The Walking Dead (2010–present) and Fear the Walking Dead (2015–present). Other films feature further other end-of-the-world scenarios, including cataclysmic natural disasters, pestilence and invasion. There are numerous examples of post-apocalypse texts, including Night of the Living Dead (Romero, 1968), Mad Max 2 (Miller, 1981), Reign of Fire (Bowman, 2002), The Day After Tomorrow (Emmerich, 2004), Children of Men (Cuaron, 2006), Left Behind (Armstrong, 2014) and Knowing (Proyes, 2009). The focus of the narrative in these texts, whether it be zombie plague or extinction-level event asteroid, is on how the characters in these stories come to terms with disaster, either before or after the apocalyptic event. Other texts examine cataclysmic events that befall the earth, such as Deep Impact (Leder, 1998), The Day After Tomorrow (2004) or 2012 (Emmerich, 2009). All these texts highlight prevailing attitudes and cultural anxieties, and can also be discussed in terms of the differences in the representation of disaster after September 11, 2001. This article examines the connection of these texts to religious prophecies from the Bible (Revelation) and how popular culture texts demonstrate an ambivalent relationship to predictions of apocalypse.
Précis
Authors: Elshahed Mohamed , Andersen Angela 
Published: June 2017

‘WRITING HISTORIES OF NOW: MODERN AND CONTEMPORARY MIDDLE EAST ART AND ARCHITECTURE’, FORUM TRANSREGIONALE STUDIEN AND DEPARTMENT OF ART AND VISUAL HISTORY (IKB), HUMBOLDT UNIVERSITY, BERLIN, GERMANY, JULY 6–7, 2015
‘BEYOND THE MOSQUE: DIVERSE SITES OF MUSLIM
PRAYER’, UNIVERSITIES ART ASSOCIATION OF CANADA/L’ASSOCIATION D’ART DES UNIVERSITÉS DU CANADA ANNUAL CONFERENCE, MONTREAL, CANADA, OCTOBER 27–30, 2016
‘I could go on forever varying goblins’: Arthur Rackham designs Hansel and Gretel, Cambridge Theatre 1933
Authors: Lennox Patricia 
Published: June 2017

Abstract
During the Christmas theatre season, 1933, Arthur Rackham, noted for his fantasy illustrations, designed sets and costumes for Humperdinck’s opera Hansel and Gretel with a limited run at the Cambridge Theatre, 26 December to 27 January, 1934. Its producer Sydney Carroll and director Basil Dean were major figures in the London theatre and accustomed to working with professionals who were costume designers in the modern sense – unlike Rackham who was an illustrator hired to put his paintings onstage. Rackham was unfamiliar with the costume process and with the theatre in general and relied heavily on the more experienced Stella Mary Pearce (later Newton) to oversee the costumes’ construction and all final steps of the process. This article explores the extent to which Rackham’s experience – and product – as a neophyte designer can be reconstructed from available archival material that includes costume designs and correspondence.
Event Reviews
Authors: Pichou Myrsini , Barford Katie , Watt Fiona , Spencer Michael 
Published: June 2017

Abstract
Costume on Stage and Screen Symposium, Athens, 18 February 2017
Costume and Fashion In Context and Practice, University of Huddersfield, United Kingdom

Drawing Theatre: Pamela Howard – An Exhibition in The Crab Studio at Arts University Bournemouth, Curated by Rebecca Pride and Co-Curated by Sam Edwards, 22 March–22 April 2016
Review of The Vulgar: Fashion Redefined – Barbican Art Gallery, 13 October 2016–5 February 2017
Book Reviews
Authors: Osmond Suzanne , Comerford Chris , Fernandez Ester Mangas 
Published: June 2017

Abstract

Unbuttoned: The Art and Artists of Theatrical Costume Design, E. Shura Pollatsek (2017)
New York: Routledge, 176 pp.,
ISBN: 9781138919037, p/bk

The Superhero Costume: Identity and Disguise in Fact and Fiction, Barbara Brownie and Danny Graydon (2016)
London and New York: Bloomsbury Academic, 175 pp.,
ISBN: 978-1-4725-9590-4, p/bk

Mute Movements: A Collective Performance Art Journey Through Beirut, 2009–2014, Cornelia Krafft (2015)
Beirut: American University of Beirut Press, 303 pp.,
ISBN13: 9789953586175, h/bk