bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transcriptome of healthy gingival tissue from edentulous sites in patients with a history of generalized aggressive periodontitis
Authors: Taiete Tiago , Casarin Renato Corrêa Viana , Ruiz Karina Gonzales Silvério , Nociti Jr. Francisco Humberto , Sallum Enilson Antônio , Casati Marcio Zaffalon 
Published: August 2017

AbstractBackgroundThis study evaluates the transcriptome of healthy gingival tissue from edentulous sites in patients with a history of generalized aggressive periodontitis (GAgP), chronic periodontitis (CP), and in patients with no history of periodontitis (H), using microarray and quantitative reverse transcription polymerase chain reaction (qRT‐PCR) analysis.MethodsHealthy gingival tissue from edentulous sites was taken from patients from the GAgP (n = 12), CP (n = 12), and H (n = 12) groups. Initially, total RNA from four tissue samples per group was used in transcriptomic microarray analysis. Differential gene expression (fold‐change), gene ontology (GO; biologic process), and pathway analyses were performed. Genes that were differentially expressed and showing a significant role on altered pathways were validated by qRT‐PCR analysis on 12 samples per group.ResultsIn total, 270 probe sets and 50 GO groups were differentially expressed (upregulated or downregulated) between GAgP and H. Natural killer cell receptors and other genes related to the immune system were upregulated in GAgP, whereas genes with functions in neural processes and in proliferation/differentiation of keratinocytes were underexpressed. There were 220 probe sets and 75 GO groups that were differentially expressed when comparing CP and GAgP. CP was characterized by increased expression of genes related to responses to external stimuli and an underexpression of immune system‐related genes. qRT‐PCR analysis confirmed microarray results, that killer cell immunoglobulin (Ig)‐like receptor, two Ig domains and long cytoplasmic tail 4; interleukin‐6; and selectin E were more highly expressed in patients from the GAgP group compared with the CP and H groups.ConclusionThis study demonstrates differences in the transcriptome of healthy gingival tissue from edentulous sites in patients with GAgP compared with patients from H or CP groups.
Prevalence of comorbidities in periodontitis patients compared with the general Austrian population
Authors: Sperr Martina , Kundi Michael , Tursic Vernes , Bristela Margit , Moritz Andreas , Andrukhov Oleh , Rausch‐Fan Xiaohui , Sperr Wolfgang R. 
Published: August 2017

AbstractBackgroundThe majority of patients with periodontitis present with comorbidities, however only little is known on prevalence of these comorbidities in comparison with the general population. This study aims to analyze the prevalence and impact of comorbidities in patients with periodontitis in Austria.MethodsPrevalence of comorbidities was evaluated in 1,199 patients with periodontitis (median age: 49, range: 14 to 83 years). These data were compared with a randomly selected age‐ and sex‐matched cohort of the Austrian population by an unconditional logistic regression model.ResultsComorbidities were found in 821 of 1,199 (68.5%) patients. Allergies had the highest prevalence (29.2%), followed by hypertension (19.4%), musculoskeletal (11.2%), and endocrine disorders (9.7%). Chronic pulmonary disorders (no influenza/pneumonia) were associated with a higher approximal plaque index (72% versus 63%, P = 0.02). No association between characteristics of periodontitis and comorbidities was observed. Prevalence of allergies (29.2% versus 22.9%) and pulmonary disorders (8.5% versus 4.3%) was significantly higher in periodontitis patients compared with the Austrian population (P < 0.001), whereas asthma (1.5% versus 5.6%), cardiovascular disorders (1.8% versus 10.5%), depression (7.1% versus 10.4%), headache (1.3% versus 20%), hyperlipidemia (6.4% versus 14.8%), hypertension (14.2% versus 24.5%), musculoskeletal disorders (11.2% versus 41.7%), and osteoporosis (2.8% versus 5.1%) were found less frequently (P < 0.001). No differences were observed for cancer, diabetes mellitus, gastrointestinal disorders, or psychiatric disorders (P = 0.95, P = 0.76, P = 0.68, P = 0.23, respectively).ConclusionIn Austria, the majority of patients with periodontitis present with comorbidities, and the adjusted prevalence differs significantly from the general population.
Gloucester's inwardness and maternal anxiety in King Lear
Authors: Ludwig Carlos Roberto 
Published: August 2017

Este ensaio discute as questões de interioridade e angústias maternas na peça King Lear de Shakespeare. Aborda também o conceito de significante, baseado nos pressupostos de Lacan. Primeiramente, apresenta os pressupostos de Lacan sobre o significante e a constituição da subjetividade. Depois disso, discute as angústias maternas partindo do trabalho de Janet Adelman (1992). Adelman estuda fantasias maternas baseadas na psicanálise Freudiana, mas nunca menciona os pressupostos de Lacan. Ela não revela os dispositivos mais profundos na interioridade de Lear que são negados e reprimidos, cujas projeções dirigidas e internas sugerem dimensões e disposições escuras do self interior de Lear. Ela só discute fantasias maternas re-imaginado com suas filhas. Para preencher essa lacuna, discuto e analiso as constelações psíquicas que se revelam nos silêncios, não-ditos e não sequituros de seus discursos, que apontam um conjunto de metáforas projetadas além da fase pré-edipiana, experimentada por Gloucester. Essa experiência não será dirigida somente a sua imagem de Edgar, mas ele projeta sua raiva para outros personagens da peça, como Edmond e suas figuras maternas. A experiência de auto-individuação poderia ser associada a uma cadeia de elementos imagéticos e paranóicos, que apontam para a perda da referencialidade, da totalidade e da centralidade da psique e, conseqüentemente, confunde e re-direciona o locus de suas projeções interiores. Segundo Lacan, o inconsciente é algo puramente lógico, em outras palavras, é algo originado do significante.
Conscientização ambiental contribuindo para eliminar o desperdício e ampliar as ações a favor do meio ambiente
Authors: Carvalho Viviane Grams , Estender Antônio Carlos 
Published: August 2017

Este trabalho se propõe a compreender as percepções dos stakeholders sobre a como a Conscientização ambiental pode contribuir para eliminar o desperdício e ampliar as ações a favor do meio ambiente e para a aplicação prática, visa também solucionar problemas específicos, no caso, do desperdício e o descarte incorreto. Tem como objetivo verificar na visão e vivência dos stakeholders; no ramo da saúde pública, os fatores importantes para o desenvolvimento de um sistema de gestão sustentável, para agregar valor à organização. O trabalho foi realizado por meio de estudo de caso, entrevistas de natureza qualitativa e exploratória, sendo a coleta de dados realizada através de um questionário destinado a 25 stakeholders. Observou-se que os principais resultados foram o desconhecimento do assunto por parte dos servidores e usuários e a falta de incentivo. Diante de o exposto as implicações, é recomendado estabelecer normas para que as entidades governamentais implantem um sistema de gestão sustentável para otimizar os recursos utilizados e ampliar a conscientização, para isso deve-se utilizar destas entidades para incentivar a conscientização ambiental da população e manter o meio ambiente saudável.
A influência da oralidade na escrita: reflexões e desafios no ensino de língua materna
Authors: BATISTA-SANTOS DALVE OLIVEIRA , Batista Pereira Elemaria 
Published: August 2017

A presente pesquisa teve por objetivo analisar a influência da linguagem oral na escrita de alunos do segundo ano do Ensino Médio e suas implicações no desenvolvimento da Língua Materna. Para tanto, buscamos responder aos seguintes questionamentos: quais as influências/marcas da linguagem oral nos textos escritos de alunos do Ensino Médio? E quais implicações dessas influências/marcas no Ensino de Língua Materna? Dessa forma, para respondermos aos questionamentos propostos, nos embasamos em pesquisadores que têm como foco a temática discutida nesta pesquisa, sendo eles: Marcuschi (2008; 2010); Fávero et al. (2000); Kato (2002); Bortoni-Ricardo (2004; 2005). Com as análises, constatamos que os alunos, mesmo estando no Ensino Médio, ainda utilizam a língua oral em seus textos escritos, o que implica em pouco conhecimento das convenções gramaticais ou pouco domínio da norma culta. Além disso, acreditamos que essa influência pode ser consequência da falta de leituras significativas e orientadas, o que acarreta em um repertório limitado.
Palavras-chave: Oralidade. Escrita. Língua Materna.
Globo Repórter no Twitter: o discurso coletivo dos telespectadores
Authors: Silva Bianca Pereira da , Golembiewski Carlos 
Published: August 2017

Este estudo tem por objetivo revelar os comentários do Twitter feitos pelos telespectadores do Globo Repórter durante a exibição do programa. Entre os objetivos específicos estão: um perfil do programa e uma análise histórica do surgimento das redes sociais. A escolha do Globo Repórter se deu porque ele é um dos programas que está há mais tempo no ar na TV brasileira. Para isso, utilizou-se como referencial teórico: Globo Repórter (Andrade, 2002); (Souza, 2004), (Rezende, 2000); Rede Social na Internet (Recuero, 2009), (Body & Ellison, 2007) e Twitter (Santaella e Lemos, 2009), (Zago,2014). Como método para desenvolver esse estudo, usou-se a técnica do Discurso do Sujeito Coletivo proposta por Lefévre&Lefévre (2003). Para desenvolver a técnica, foram analisadas duas edições do Globo Repórter e coletados os comentários dos telespectadores por meio da hashtag #GloboReporter, durante a exibição do programa. Entre as conclusões, pode-se dizer que ao assistir o Globo Repórter, a população relaciona a sua realidade com aquilo que é exibido no programa.
EPISTEMOLIGIA DA PRODUÇÃO DO ESPAÇO LEFEBVRIANO
Authors: Silveira Elisabete Ferreira 
Published: August 2017

A epistemologia é a ciência relacionada à prática do conhecimento, para qual o método é fundamental ao conhecimento científico. Este artigo lança-se sobre a problemática da epistemologia da teoria da produção do espaço e seu rebatimento filosófico nas Ciências Sociais. Objetivamente, buscamos traçar notas acerca da epistemologia da teoria da produção do espaço de Henri Lefebvre com relevo a sua significância à Geografia. Para tanto, recorreremos a leitura da sua obra de mesmo nome La producción del espacio, bem como revisão da literatura pertinente e de informações já publicadas e disponíveis em impressos ou meio eletrônico, acerca da episteme, do conceito de espaço e de sua produção capitalista, do urbano e da própria teoria de Lefebvre. Em síntese, a teoria discutida não se resumo apenas a uma obra, se insere numa produção sobre a cidade, o espaço e o urbano que carrega consigo as marcas da observação e interpretação do seu tempo. Seu autor buscou, através do seu método e métodos de procedimento, construir um projeto de conhecimento simultaneamente descritivo, analítico e global que redundasse numa teoria sobre a produção do espaço urbano.
Palavras-chave: Epistemologia. Produção do Espaço. Henri Lefebvre.
Basic Static Code Analysis Untuk Mendeteksi Backdoor Shell Pada Web Server
Authors: Widiastuti Nelly Indriani , Iqbal Muhammad 
Published: August 2017

Mengakses sistem komputer tanpa ijin merupakan kejahatan yang dilakukan dengan memasuki atau menyusup kedalam suatu sistem jaringan komputer tanpa sepengetahuan dari pemilik sistem tersebut. Kejahatan tersebut bertujuan untuk mengintai atau mencuri informasi penting dan rahasia. Dalam praktiknya peretas menyisipkan berkas backdoor shell pada lokasi yang sulit ditemukan oleh pemilik sistem. Beberapa perangkat yang sudah ada masih dalam bentuk terminal. Perangkat tersebut melakukan pencarian berkas berdasarkan nama-nama yang telah terdaftar sebelumnya. Akibatnya, pada saat berkas backdoor shell jenis baru menginfeksi, tools tersebut tidak dapat mendeteksi keberadaannya. Berdasarkan hal tersebut, maka dalam penelitian ini pencarian backdoor shell pada web server menggunakan metode basic static code analysis. File sistem diproses melalui dua tahap utama yaitu string matching dan taint analysis. Dalam proses taint analysis, sistem menghitung peluang kemungkinan setiap signature sebagai backdoor untuk mengatasi kamus backdoor yang tidak lengkap. Berdasarkan hasil yang didapat dari pengujian yang dilakukan terhadap 3964 berkas diperoleh tingkat akurasi yang lebih besar dibandingkan dengan aplikasi php shell detector sebesar 75%.
Using a Resin-Only Solution to Complete a Permanent Abandonment Operation in the Gulf of Mexico
Authors: Davis John E. 
Published: August 2017

Abstract
This paper describes the successful application of a rigless well abandonment method that isolated the well's production interval using resin-based sealant, without cement and without latching a conventional subsea blowout preventer (BOP).
An offshore operator needed to permanently abandon a subsea well that had become uneconomic due to excessive sand production. Several subsea wellhead and downhole conditions would have made killing the well by conventional means difficult if not impossible. Wellhead fatigue and soil erosion around the wellhead meant that a conventional drilling BOP could not be used in the operation due to the equipment's weight. Fluids to kill the well and permanently seal the formation could only be pumped down the tubing, and an obstruction in the flow path would limit the injection rate. Typical wireline and coiled tubing intervention tooling and circulation could not be used. Cement and micro-cement have particles that could potentially bridge at the downhole obstruction, preventing it from sealing the formation.
Considering these factors, the operator and service provider designed, tested, obtained regulatory approval, and successfully implemented a rigless abandonment operation using a service vessel and well stimulation tool to inject resin-based sealant into the well to seal the formation and enable safe final abandonment and tree removal using a light intervention vessel. These results suggest that this method can potentially be used during abandonment of subsea wells with smaller trees and wellheads that have experienced fatigue.
Utilizing a 15,000psi Rig to Drill an 18,000psi Ultra HPHT Reservoir: A Drilling Contractor's Perspective
Authors: Solarin A. O. , Golovinskij N. , Ozturk S. 
Published: August 2017

Abstract
On the Solaris Ultra-High Pressure-High Temperature exploration well drilled in the NCS in 2016, a 15.0 psi rated rig, the Maersk Gallant jack-up (MSC-CJ62-120S design), was adapted to drill a reservoir with a Maximum Expected Wellhead Pressure (MEWHP) in excess of 16,600psi.
The primary goal was to refit the rig to accept and operate in line with applicable PSA requirements, a 20.0 psi rated double BOP ram to be used in conjunction with the rig's 15,000 psi BOP. The scope included the installation of two different MPD annular pressure control systems. The modifications were to be carried out without stopping operations and within budget.
An extensive, collaborative well-planning and equipment preparation process involving the operator (client), drilling contractor and service providers was critical to the success of the overall operation. Within the drilling contractor organization, the rig team, Technical Organization, Asset Team and Operations Drilling Support worked together to ensure all requirements and risk mitigating measures were in place and lessons learned from previous HPHT/MPD operations were incorporated.
Some rig modifications were executed while in operation on another project under contract with another operator. Such jobs were limited to pulling cables and mechanical preparations to expedite hot work required at later stages.
This paper describes the key planning considerations, preparations and creative solutions deployed to deliver a complex project which culminated in successfully drilling the deepest, hottest and highest pressure well in Norwegian history. It will serve as a reference for planning future Ultra HPHT projects. No confidential operational or subsurface data is revealed in this paper.
A Variable U Value Flowline Solution for Life-of-Field Thermal Management of Conventional and HPHT Fields
Authors: Watt Sam , Paul Samuel 
Published: August 2017

Abstract
Thermal management of subsea field developments takes a variety of approaches depending of the nature of the reservoir fluid and the distance over which it is being transported. Current solutions, often relatively high in CAPEX and/or OPEX, are a compromise to cater for the extreme ends of field life. They include passive coatings (wet and dry insulation), active heating systems (e.g. hot water circulation or electrical heating), cooling or warming spools, and chemical injection. Once installed their performance is generally fixed and are thus specified conservatively.
This paper outlines the details of a flowline thermal management solution in which the overall heat transfer coefficient (U-value) can be varied as and when required by the field operator to meet the changing field conditions.
By changing the pressure in a pipe-in-pipe (PiP) annulus, the rate of heat transfer to the ambient seawater can be varied. Increasing the pressure can significantly increase the heat transfer, thereby cooling the transported fluid and removing the need for large and expensive cooling spools. Reducing the pressure reduces the heat transfer, enabling the fluid to be kept above the hydrate formation and wax appearance temperatures at lower turndown rates, over longer distances.
Reducing the pressure below atmospheric provides a thermal management solution that requires minimal or indeed no physical insulation, with the associated savings in CAPEX.
This variable solution is ideally suited for HPHT fields where the fluid temperature, pressure and flowrates will vary significantly over the field life. It is also likely to be cost-effective for all field developments requiring thermal management, by maximising the operating envelope and removing system design constraints. The temperature control allows for the tie-in of future fields where the flow conditions may otherwise require a different and more costly development strategy.
There are both initial and operational cost savings and benefits that can be realised through the variation of just a single pressure parameter: Lower turndown ratesExtended field lifeExtended no-touch timesReduced insulation system costReduced chemical injection requirementsNo requirement for expensive cooling or warming spoolsNo compromise on production flowrates due temperature limitations of the host facility
In summary, the whole thermal performance of the system can be managed by changing only the annulus pressure, which can be performed from the topside, putting thermal control in the hands of the operator.
Full scale testing has been carried out to verify the subsea system and the associated design models for the market.
The Deployment of Ceramic Membrane Technology to Treat Stable Oil in Emulsions in Produced Water Offshore
Authors: Dunsmuir I. , Guthrie G. , Cottrell T. , Nijmeijer A. , Reck B. Gydesen 
Published: August 2017

Abstract
In a significant number of oil and gas fields, production chemicals like corrosion inhibitors are continuously injected subsea at the wells and can cause issues with produced water quality. Corrosion inhibitors are generally injected to prevent corrosion in carbon Steel flow lines and can operate by the formation of a chemical film barrier along the interior surface of the flow line. However, when the fluids mix at the production facility the chemical interactions of the oil, inhibitor and water can create a tight emulsion that is extremely challenging to remove from the produced water. Existing water and oil separation treatment equipment is quite commonly unable to separate the water from the hydrocarbons in this emulsion as droplet sizes are often &lt; 10 µm, resulting in produced water with non-compliant dispersed oil in water (OiW) content for overboarding. After extensive testing of a large range of technologies, ceramic membrane technology turned out to be one of the most suitable technologies to treat the produced water down to compliant levels required by the OSPAR regulations, &lt; 30 mg/l dispersed OiW.
The information that will be presented in the presentation is real-life operational data from pilot tests as well as the first of its kind full field commercial deployment of Liqtech/Semco silicon carbide (SiC) ultrafiltration membrane technology for offshore OiW removal. This first full field application will likely pave the way for further deployment of this technology in (offshore) oil and gas operations.
A Novel Two-Stage Approach to On-Site Condition Monitoring for the Avoidance of Unscheduled Down-Time, Critical Equipment Failure and Costly False Alarms
Authors: Leavers V. 
Published: August 2017

Abstract
The two-stage condition monitoring approach takes account of the fact that, due to the advent of improved lubricant formulations and more efficient filter designs, conventional laboratory oil testing has recently become less useful for extracting timely condition monitoring information. The new approach uses the latest technological advances in imaging hardware combined with ASTM D7684-11 compliant wear debris particle analysis software containing an extensively researched knowledge base that has captured the diagnostic skills and experience of a number of expert wear debris analysts, each with decades of hands-on experience. It offers a cost effective, on-site diagnostic capability to rival that of most specialist labs. First stage testing uses the latest computer vision technology to visualise fine debris. This innovative digital imaging hardware enables on-site maintenance professionals not only to reliably size and count but also to analyse wear debris particles as small as 5 microns, offering timely equipment health information that few laboratories can match. The second stage consists of on-site, in-service filter analysis triggered by the appearance of abnormalities in the fine debris particles during first stage analyses. The innovative, diagnostic wear debris particle analysis software then uses the five level severity rating advocated by the ASTM D7684-11 standard guide such that timely alerts do not allow wear to escalate to a critical level. The paper includes the results of a forensic case study illustrating the way in which a catastrophic bearing failure, costing millions of euros in critical equipment down-time could easily have been avoided had the two-stage condition monitoring methodology been applied. This new approach has the potential to avoid costly, unscheduled, equipment down-time due to the unpredicted failure of critical equipment or equally costly false alarms when equipment is unnecessarily removed from service. This is accomplished by extracting information concerning equipment health from fine wear debris at an early stage in the wear process, where such information has previously only been available by the analysis of large wear debris particles at a much later stage in the equipment wear cycle.