bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multichannel Modified Covariance Estimator of a Single-Tone Frequency
Authors: Chyrka I. D. , Omelchuk I. P. 
Published: January 2016

Abstract
The multichannel modified covariance estimator of a single-tone signal frequency is synthesized by using the maximum likelihood method. It is shown that this estimator has an advantage over the estimator averaged by multiple conventional single-channel ones. The particular case of a complex signal is also considered.
Fusion of Images Generated by Radiometric and Active Noise SAR
Authors: Kudriashov Volodymyr V. , Garbar Artem Y. , Lukin Konstantin A. , Maslikowski Lukasz , Samczynski Piotr , Kulpa Krzysztof S. 
Published: January 2016

Abstract
The work is devoted to fusion of radar and radiometer images. Noise waveform SAR generates radar images of reflective objects of its field of view. A bistatic radiometer with synthetic aperture estimates the thermal radio emissions of the objects along their angular coordinates and even range. The estimated brightness temperatures of rough and smooth surfaces are different, as well as the radar responses from them. Identification of the parameters of objects surfaces may be done using results of joint processing of images generated by both sensors. The optimum and quasi-optimum criteria for fusion of the images were obtained. The latter was experimentally checked. It approves the opportunity to fuse the images for further estimation of some parameters of objects surfaces. The results obtained may be used in environmental and security applications.
Balanced line bundles on Fano varieties
Authors: Lehmann Brian , Tanimoto Sho , Tschinkel Yuri 
Published: January 2016

Abstract
A conjecture of Batyrev
and Manin relates arithmetic properties of varieties with
ample anticanonical class to geometric invariants. We analyze the geometry underlying these invariants using the Minimal Model Program and then apply our results to primitive Fano threefolds.
A Framework to Determine the Upper Bound on Extractable Power as a Function of Input Vibration Parameters
Authors: Heit John D. , Roundy Shad 
Published: January 2016

Abstract
This paper outlines a mathematical framework to determine the upper bound on extractable power as a function of the forcing vibrations. In addition, the method described provides insight into the dynamic transducer forces required to attain the upper bound. The relationship between vibration parameters and transducer force gives a critical first step in determining the optimal transducer architecture for a given vibration source. The method developed is applied to three specific vibration inputs: a single sinusoid, the sum of two sinusoids, and a single sinusoid with a time-dependent frequency. As expected, for the single sinusoidal case, the optimal transducer force is found to be that produced by a resonant linear spring and a viscous damping force, with matched impedance to the mechanical damper. The resulting transducer force for the input described by a sum of two sinusoids is found to be inherently time dependent. The upper bound on power output is shown to be twice that obtainable from a linear harvester centered at the lower of the two frequencies. Finally, the optimal transducer force for a sinusoidal input with a time-dependent frequency is characterized by a viscous damping term and a linear spring with a time-dependent coefficient.
Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition
Authors: Whitehead Rebecca , Guan Haiyan , Arany Edith , Cernea Maria , Yang Kaiping 
Published: January 2016

Abstract

Background: Exposure to bisphenol A (BPA), an endocrine disrupting chemical, during gestation is associated with a variety of metabolic dysfunctions in adulthood, including hyperinsulinemia, glucose intolerance and insulin resistance. These modifications in glucose homeostasis largely stem from alterations in pancreatic function. However, the effects of BPA on the fetal pancreas have never been explored. The present study addressed this important question by examining the effects of prenatal BPA exposure on the mouse fetal pancreatic development.

Materials and methods: Pregnant mice were fed a BPA diet (25 mg BPA/kg diet) from embryonic day 7.5 (E7.5) to E18.5. At E18.5, fetal pancreata were collected and analyzed for morphological changes in the endocrine pancreas such as islet size, number and β and α cell distribution.

Results: We showed that BPA exposed fetal pancreata had a greater number of islet-cell clusters (ICCs; <300 μm2; p<0.05) compared with controls. Furthermore, immunohistochemical analysis revealed that prenatal BPA exposure increased both glucagon expression in islets and the numbers of glucagon-expressing islet-cell clusters (p<0.05).

Conclusion: Considering that ICCs represent the initial stages of islet development in the fetal pancreas, our findings suggest that BPA promotes islet differentiation or delays the conversion of ICCs into mature islets. Moreover, the increase in glucagon expression suggests a potential alteration in the α:β-cell ratio in islets, which may have significant implications for the fetal pancreas both structurally and functionally. This study provides novel insight into the effects of BPA exposure on the fetal pancreata, indicating alterations in glucagon expression in islets and ICCs.
Spontaneous conception following GnRHa and progestogen therapy in adenomyosis
Authors: Dasrilsyah Rima Anggrena , Shan Lim Pei , Kwang Ng Beng , Shafiee Mohamad Nasir , Omar Mohd Hashim 
Published: January 2016

Abstract
Adenomyosis is a common gynaecological disorder that is associated with infertility and miscarriage. We report a case of adenomyosis presented with urinary retention and infertility. The patient successfully conceived spontaneously following GnRHa followed by progestogen therapy. This treatment option might provide a synergistic effect in improving fertility and pregnancy outcome for women with adenomyosis. This modality has no potential surgical risk; it minimises the long-term side effects of GnRHa and also provides luteal support.
Trichoderma viride and Pseudomonas fluorescens CHA0 against Meloidogyne javanica in the rhizosphere of tomato plants
Authors: Saeedizadeh A. 
Published: January 2016

Summary
Root-knot nematodes are among the most important pests that reduce tomato yield in greenhouses and fields in Iran. The scope of this research was to evaluate the antagonistic effect of Trichoderma viride and Pseudomonas fluorescens CHA0 on the reproduction and galling rate of Meloidogyne javanica in tomato roots. A pot experiment was conducted on seedlings of tomato cultivars Bony best, Falat, Mobile and Walter grown in sterilized sandy loam soil. Inocula used for artificial inoculation were 3 J2/g of soil for the nematode, 1×106 spores/ml for the fungus and 1×109 cfu/ml for the bacterium. The nematicide RUGBY® 10 G (cadusafos) was used as a reference product at 2g per each pot. Two months after inoculation, the number of knots and egg masses per root in the treatments were (with descending order): control (nematode), nematode+bacterium, nematode+fungus, nematode+fungus+bacterium and nematode+nematicide. The combination fungus+bacterium enhanced the biocontrol effect against M. javanica activity as compared to the fungus and bacterium stand-alone treatments except for the cases of the cultivars Mobile and Bonny best in which the effect was similar to the one by the fungus alone. The fungus + bacterium combined treatment was equally effective to the nematicide treatment for all cultivars. The highest and lowest rate of nematode activity was observed in Walter and Mobile cultivars, respectively.
Testing Equality in Ordinal Data with Repeated Measurements: A Model-Free Approach
Authors: Lui Kung-Jong 
Published: January 2016

Abstract
In randomized clinical trials, we often encounter ordinal categorical responses with repeated measurements. We propose a model-free approach with using the generalized odds ratio (GOR) to measure the relative treatment effect. We develop procedures for testing equality of treatment effects and derive interval estimators for the GOR. We further develop a simple procedure for testing the treatment-by-period interaction. To illustrate the use of test procedures and interval estimators developed here, we consider two real-life data sets, one studying the gender effect on pain scores on an ordinal scale after hip joint resurfacing surgeries, and the other investigating the effect of an active hypnotic drug in insomnia patients on ordinal categories of time to falling asleep.
Crystal structure of bis[4-(3-carboxy-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinolin-7-yl)piperazin-1-ium] benzene-1,4-dicarboxylate (C20H18F2N3O3)2(C8H4O4), C48H40F4N6O10
Authors: An Zhe , Zhu Ling , Zhao Xin-Hua 
Published: January 2016

Abstract
C48H40N6O10F4, monoclinic, C2/c
a = 29.701(2) Å, b = 11.1940(8) Å, c = 13.1275(9) Å, β = 97.393(6)°, V = 4328.2(5) Å3, Z = 4, R
gt
(F) = 0.0462, wR
ref
(F
2
) = 0.1337, T = 296 K.
Crystal structure of 3-(thiophen-2-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazole-1-carboxamide
Authors: Barakat Assem , Shivalingegowda Naveen , Renuka Nagamallu , Kariyappa Ajay Kumar , Abdoh Muneer , Warad Ismail , Lokanath Neratur Krishnappagowda 
Published: January 2016

Abstract
C15H15N3OS, monoclinic, P21/c (No. 14), a = 10.2852(5) Å, b = 10.1649(5) Å, c = 14.7694(8) Å, β = 107.442(2)°, V = 1473.12(13) Å3, Z = 4, R
gt
(F) = 0.0449, wR
ref
(F
2
) = 0.1275, T = 293(2) K.
Indicating verbs in British Sign Language favour motivated use of space
Authors: Cormier Kearsy , Fenlon Jordan , Schembri Adam 
Published: January 2016

AbstractSign languages have traditionally been described as having a distinction between (1) arbitrary (referential or syntactic) space, considered to be a purely grammatical use of space in which locations arbitrarily represent concrete or abstract subject and/or object arguments using pronouns or indicating verbs, for example, and (2) motivated (topographic or surrogate) space, involving mapping of locations of concrete referents onto the signing space via classifier constructions. Some linguists have suggested that it may be misleading to see the two uses of space as being completely distinct from one another. In this study, we use conversational data from the British Sign Language Corpus (www.bslcorpusproject.org) to look at the use of space with modified indicating verbs – specifically the directions in which these verbs are used as well as the co-occurrence of eyegaze shifts and constructed action. Our findings suggest that indicating verbs are frequently produced in conditions that use space in a motivated way and are rarely modified using arbitrary space. This contrasts with previous claims that indicating verbs in BSL prototypically use arbitrary space. We discuss the implications of this for theories about grammaticalisation and the role of gesture in sign languages and for sign language teaching.
Effects Of Gelatine-Coated Vascular Grafts On Human Neutrophils
Authors: Meyer Frank , Buerger Thomas , Halloul Zuhir , Lippert Hans , König Brigitte , Tautenhahn Joerg 
Published: January 2016

Abstractwas to investigate the immune-modulatory potential of commercially available PTFE and polyester vascular grafts with and without gelatine-coating. The biomaterial-cell-interaction was characterized by changes of established parameters such as PMN-related receptors/mediators, phagocytosis potential and capacity as well as the effect of an additional plasma-dependent modulation.By means of a standardized experimental in vitro model, various vascular graft material (PTFE/polyester/uncoated/gelatine-coated) was used for incubation with or without plasma and co-culturing with human neutrophile granulocytes (PMN) followed by analysis of representative receptors and mediators (CD62L, CD11b, CXCR2, fMLP-R, IL-8, Elastase, LTBComparing the vascular grafts, un-coated PTFE induced the lowest magnitude of cell stimulation whereas in case of gelatine-coating, cell response exceeded those of the other vascular grafts. This was also found comparing the polyester-based prosthetic material. Gelatine-coated polyester led to a more pronounced release of elastase than gelatine-coated PTFE and the uncoated materials. The results of oxidative burst indicated a reduced phagocytosis capacity in case of gelatine-coated polyester. Plasma incubation did also provide an impact on the cellular response. While in case of gelatine-coating, PMN-related receptor stimulation became lower, it increased by native polyester. The latter one did also induce more mediators such as IL-8 and LTBThere have been no extensive data on cell-cell interactions, cytokines and general histo-/hemocompatibility of human cells by the new generation of vascular grafts. It remains still open whether healing process and infectious resistance can be compromised by material-dependent over-stimulation or reduced phagocytosis potential of the immune cells of the primary unspecific immune response induced by gelatine-coated materials.
Patients’ Awareness Of The Prevention And Treatment Of Colorectal Cancer*
Authors: Dziki Łukasz , Puła Anna , Stawiski Konrad , Mudza Barbara , Włodarczyk Marcin , Dziki Adam 
Published: January 2016

Abstractwas to assess patients’ awareness of the prevention and treatment of colorectal cancer.Patients diagnosed with colorectal cancer, hospitalised at the Department of General and Colorectal Surgery of the Medical University in Łódź during the period from January 2015 to April 2015, were asked to complete a questionnaire concerning their families’ medical case record, factors predisposing them to the development of colorectal cancer, the tests applied in diagnostics, and the treatment process. The questionnaire comprised 42 closed-ended questions with one correct answer. A statistical analysis of all answers was carried out.The study group consisted of 30 men and 20 women aged 27–94 years old. A strong, statistically significant negative correlation between a patient’s age and his/her awareness of the prevention and treatment of colorectal cancer was noted (p<0.001; r= −0.51). The study demonstrated a statistically significant relationship between the occurrence of neoplasms in a patient’s family (p=0.009) or, more specifically, the occurrence of colorectal cancer (p=0.008), and the awareness of the prevention programme. The women’s group was characterised by statistically significantly greater awareness of colonoscopy as a screening examination (p=0.004).Patients need more information on colorectal cancer, its risk factors, prevention, the treatment process, and postoperative care. Lack of awareness of the colorectal cancer issue can be one of the major factors contributing to the high incidence of this disease.
The Use Of The VEINES-QOL/Sym Questionnaire In Patients Operated For Varicose Veins
Authors: Migdalski Łukasz , Kuzdak Krzysztof 
Published: January 2016

AbstractVenous insufficiency is a common, chronic disease that affects nearly half of the population in highly developed countries. The vast majority of affected patients suffer from varicose veins (VV). Recently, the priority in medicine has been patient satisfaction with treatment and high quality of life. Therefore, disease-specific questionnaires that measure quality of life have been developed. One of these is VEINES-QOL/Sym with two subscales that assess quality of life and disease symptoms. To date, it has been used to examine patients with venous ulcers and thrombosis. No data are available concerning the use of VEINES to assess patients after VV surgery.was to investigate the change in QOL after VV surgery and verify the usefulness of VEINES in daily phlebological practice.The study recruited 69 patients (CEAP class C2-C3) in need of surgery for VV. The patients responded 2 hours before surgery and after 3 months. Patients were differentiated into several categories according to CEAP stage, age, sex, BMI, the use/lack of compression therapy, and education level.The quality of life increased significantly in C3 patients and in patients over the age of 50. Quality of life increased significantly in all patients regardless of education. There were no differences between groups differentiated according to sex, the use or lack of compression therapy, or BMI.The VEINES-QOL/Sym questionnaire can be used in daily phlebological practice to assess patients before and after surgical treatment of VV. VEINES-QOL/Sym is reliable and highly valid.
The Use Of Negative Pressure Wound Therapy (NPWT) In The Management Of Enteroatmospheric Fistula – Case Report And Literature Review
Authors: Jaguścik Rajmund , Walczak Dominik A. , Porzeżyńska Joanna , Trzeciak Piotr W. 
Published: January 2016

AbstractAn enteric fistula that occurs in an open abdomen is called an enteroatmospheric fistula (EAF) and is the most challenging complication for a surgical team to deal with. The treatment of EAF requires a multidisciplinary approach. First of all, sepsis has to be managed. Any fluid, electrolyte and metabolic disorders need to be corrected. Oral intake must be stopped and total parenteral nutrition introduced. The control and drainage of the effluent from the fistula is a separate issue. Since there are no fixed algorithms for the treatment of EAF, surgeons need to develop their own, often highly unconventional solutions.We present the case of a 24-year-old man who developed enteroatmospheric fistula after laparotomy and relaparotomy due to acute necrotic pancreatitis. Both the laparostomy and the fistula were successfully managed using modified negative pressure wound therapy. The literature regarding this issue was also reviewed.
Invasiveness of Listeria monocytogenes strains isolated from animals in Poland
Authors: Wałecka-Zacharska E. , Kosek-Paszkowska K. , Bania J. , Staroniewicz Z. , Bednarski M. , Wieliczko A. 
Published: January 2016

AbstractAnimals are important reservoir ofListeria monocytogenes, a pathogen causing serious infections in both humans and livestock. However, data on invasiveness ofL. monocytogenesstrains of animal origin is very scarce. Ability of 18L. monocytogenesstrains of animal origin to invade HT-29 cells was investigated. Plaque forming assay was used to assess invasiveness and ability of the pathogen to spread in the cell line. Almost 40% ofL. monocytogenesstrains were weakly invasive. It was shown that strains from serogroup 4b exhibited the highest invasiveness, whereas serogroup 1/2b consisted of strains of invasiveness below 0.0001%. Analysis of translatedinlAandinlBgene sequences revealed no premature stop codons. Lineage-specific mutations in low invasive strains were identified withininlAandinlBsequences. Our results demonstrate high incidence of low invasive animalL. monocytogenesstrains, which may be at least partly explained by unique point mutations in the InlA and InlB.
A multiplex PCR for simultaneous detection of classical swine fever virus, African swine fever virus, highly pathogenic porcine reproductive and respiratory syndrome virus, porcine reproductive and respiratory syndrome virus and pseudorabies in swines
Authors: Hu L. , Lin X.Y. , Yang Z.X. , Yao X.P. , Li G.L. , Peng S.Z. , Wang Y. 
Published: January 2016

Abstract
In this assay, we developed and evaluated a multiplex PCR (mPCR) for its ability in detecting multiple infections of swine simultaneously. Four pairs of primers were used to detect five viruses. Specific primers were designed for classical swine fever virus (CSFV), African swine fever virus (ASFV) and pseudorabies (PRV). A pair of primers was designed prudently for two different types of porcine reproductive and respiratory syndrome virus that respectively were porcine reproductive and respiratory syndrome virus (PRRSV), highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV). The detection limits of the mPCR were 1.09×104, 1.50×103, 2.10×103, 1.30×103 and 8.97×102 copies/reaction for CSFV, ASFV, HP-PRRSV, PRRSV and PRV, respectively. A total of 49 clinical specimens were tested by the mPCR, and the result showed that co-infection by two or three viruses was 51%. In conclusion, the PCR is a useful tool for clinical diagnosis of not only single infections but also mixed infections in swines.
Is downer cow syndrome related to chronic botulism?
Authors: Rulff R. , Schrödl W. , Basiouni S. , Neuhaus J. , Krüger M. 
Published: January 2016

Abstract
The present work was directed to investigate the relationship between Downer cow syndrome (DCS) and chronic botulism in dairy cattle. For this purpose, a total of 52 fresh calving downer cows and 206 apparently healthy cows at 14 dairy farms were investigated for Clostridium botulinum ABE and CD antibody levels, C. botulinum and botulinum neurotoxin in rumen fluids as well as in faeces. Results indicated that the downer cows had higher IgG titers for C. botulinum ABE and CD than the healthy cows. All tested rumen fluids were negative for BoNT and C. botulinum. BoNT/D, however, and C. botulinum type D spores were detected in faecal samples of healthy and downer cows in the selected farms. In conclusion, the presence of a significantly higher C. botulinum ABE and CD antibody levels in DCS cows than in the healthy animals suggests that chronic C. botulinum toxico-infection could be a predisposing factor for DCS.
Biofilm-formation by Staphylococcus aureus and Staphylococcus epidermidis isolates from subclinical mastitis in conditions mimicking the udder environment
Authors: Seixas R. , Varanda D. , Bexiga R. , Tavares L. , Oliveira M. 
Published: January 2016

AbstractStaphylococcusis the genus most commonly isolated from bovine mastitis in many countries. It may express several virulence factors including biofilm formation, which may protect the bacterial community from antimicrobials’ action, preventing these compounds from reaching its interior, where they reach subinhibitory concentrations (subMIC).Most biofilm production assays are performed in static conditions, while studies regarding antimicrobial resistance usually do not resemble the udder environment because they are performed at high concentrations. In this study we evaluated the influence of dynamic conditions and media, including Mueller Hinton Broth (MHB) and UHT whole milk (WM), as well as the effect of subMIC concentrations of five different antimicrobial agents on biofilm formation by staphylococci isolated from subclinical mastitis. Results suggest that dynamic conditions and media may influence biofilm formation and revealed that milking simulation may significantly increase biofilm production. Sub-MIC concentrations decrease biofilm formation in MHB but increase in WM, suggesting a protective role of milk against antimicrobial compounds’ action. Therefore,in vitroconditions that simulate the udder environment andin vivoconditions should be included as one of the parameters in evaluation of biofilm producing strains, in order to provide more reliable results.