bluuebunny/crossref_metadata_2025_split huggingface dataset:
Active Surveillance Cultures and Decolonization to Reduce Staphylococcus aureus Infections in the Neonatal Intensive Care Unit
Authors: Popoola Victor O. , Colantuoni Elizabeth , Suwantarat Nuntra , Pierce Rebecca , Carroll Karen C. , Aucott Susan W. , Milstone Aaron M. 
Published: January 2016

BACKGROUNDStaphylococcus aureus is a common cause of healthcare-associated infections in neonates.OBJECTIVETo examine the impact of methicillin-susceptible S. aureus (MSSA) decolonization on the incidence of MSSA infection and to measure the prevalence of mupirocin resistance.METHODSWe retrospectively identified neonates admitted to a tertiary care neonatal intensive care unit (NICU) from April 1, 2011, through September 30, 2014. We compared rates of MSSA-positive cultures and infections before and after implementation of an active surveillance culture and decolonization intervention for MSSA-colonized neonates. We used 2 measurements to identify the primary outcome, NICU-attributable MSSA: (1) any culture sent during routine clinical care that grew MSSA and (2) any culture that grew MSSA and met criteria of the National Healthcare Safety Network’s healthcare-associated infection surveillance definitions. S. aureus isolates were tested for mupirocin susceptibility. We estimated incidence rate ratios using interrupted time-series models.RESULTSBefore and after the intervention, 1,523 neonates (29,220 patient-days) and 1,195 neonates (22,045 patient-days) were admitted to the NICU, respectively. There was an immediate reduction in the mean quarterly incidence rate of NICU-attributable MSSA-positive clinical cultures of 64% (incidence rate ratio, 0.36 [95% CI, 0.19–0.70]) after implementation of the intervention, and MSSA-positive culture rates continued to decrease by 21% per quarter (incidence rate ratio, 0.79 [95% CI, 0.74–0.84]). MSSA infections also decreased by 73% immediately following the intervention implementation (incidence rate ratio, 0.27 [95% CI, 0.10–0.79]). No mupirocin resistance was detected.CONCLUSIONActive surveillance cultures and decolonization may be effective in decreasing S. aureus infections in NICUs.Infect. Control Hosp. Epidemiol. 2016;37(4):381–387
“Their Only Words of English Were ‘Thank You’”: Rights, Gratitude and ‘Deserving’ Hungarian Refugees to Britain in 1956
Authors: Taylor Becky 
Published: January 2016

AbstractThe Soviet invasion of Hungary in late October 1956 resulted in the exodus of approximately two hundred thousand Hungarians, of whom approximately twenty-one thousand came to Britain within a matter of weeks. This article historicizes the process of reception and resettlement of Hungarian refugees in Britain. Through exploring the rhetoric used and attitudes displayed during the reception and resettlement process, it considers if and how legally recognized rights established for refugees under the 1951 UN Convention mediated their arrival and treatment. It finds a failure of a new discourse of rights to permeate the language surrounding their reception. Instead, well-worn tropes of the generosity of the British and their traditions of tolerance and hospitality were deployed consistently at national and local levels. This had the effect of implying that entry to Britain was a privilege and one not to be abused, and it marginalized refugees who failed to conform to particular expectations. The article argues that tying attitudes toward Hungarian refugees—variously positioned as “grateful” or “ungrateful”—can be usefully understood within the context of broader conceptions of the “deserving” and “undeserving” poor and their relationship with the (welfare) state. Consequently, along with exploring the experiences of reception and resettlement of Hungarians in 1956/7 the article contributes to understandings of behavior, rights, and welfare in postwar Britain.
The Phantom Airship Panic of 1913: Imagining Aerial Warfare in Britain before the Great War
Authors: Holman Brett 
Published: January 2016

AbstractIn late 1912 and early 1913, people all over Britain reported seeing airships in the night sky, yet there were none. It was widely assumed that these “phantom airships” were German Zeppelins, testing British defenses in preparation for the next war. The public and press responses to the phantom airship sightings provide a glimpse of the way that aerial warfare was understood before it was ever experienced in Britain. Conservative newspapers and patriotic leagues used the sightings to argue for a massive expansion of Britain's aerial forces, which were perceived to be completely outclassed by Germany's in both number and power. In many ways this airship panic was analogous to the much better known 1909 dreadnought panic. The result was the perfect Edwardian panic: the simultaneous culmination of older fears about Germany and the threat of espionage, invasion, and, above all, the loss of Britain's naval superiority. But, in reality, there was little understanding about the way that Zeppelins would be used against Britain in the First World War—not to attack its arsenals and dockyards, but to bomb its cities.
Voices from the Far North: Pauper Letters and the Provision of Welfare in Sutherland, 1845–1900
Authors: Jones Peter , King Steven 
Published: January 2016

AbstractThis article explores the changing relationship between paupers and the parish authorities in Tongue, in the far north of Scotland, between the passing of the Scottish New Poor Law in 1845 and the end of the nineteenth century. It does so by focusing on Scottish pauper letters and petitions for relief. Such sources, though relatively abundant in the archives, have so far been ignored by welfare historians. The article begins with a discussion of the trials of Tongue's poor crofting community in the early years of the century, the impact of widespread land clearance, and the dislocation of long-established communities. Following on from this, through a close reading of pauper appeals alongside other official sources the authors demonstrate that, despite persistent hardship and inadequate resources, the relationship between paupers and the parish authorities changed markedly over the period. An attitude of supplication and entreaty, rooted in Highland traditions of deference and reflective of a rigid social hierarchy, gave way to a clear sense of entitlement and an expectation that paupers' appeals would—indeed, must—be heard toward the end of the century. This fundamental shift mirrored, and was profoundly influenced by, wider agitation among crofting communities for change.
Steady-State Response to Periodic Excitation in Fractional Vibration System
Authors: Huang C. , Duan J.-S. 
Published: January 2016

AbstractThe steady-state response to periodic excitation in the linear fractional vibration system was considered by using the fractional derivative operator . First we investigated the response to the harmonic excitation in the form of complex exponential function. The amplitude-frequency relation and phase-frequency relation were derived. The effect of the fractional derivative term on the stiffness and damping was discussed. For the case of periodic excitation, we decompose the periodic excitation into a superposition of harmonic excitations by using the Fourier series, and then utilize the results for harmonic excitations and the principle of superposition, where our adopted tactics avoid appearing a fractional power of negative numbers to overcome the difficulty in fractional case. Finally we demonstrate the proposed method by three numerical examples.
Landscape development and settlement history of the Vecht area (722–1122)
Authors: Buitelaar A.L.P. , Borger Guus J. 
Published: January 2016

AbstractBased on historical evidence a description in broad outline is provided of landscape and settlement development in the Vecht area north of Utrecht for the period 722–1122 AD. Although the fluvial activity of the Vecht channel was reduced from about 2300 BP onwards, the river retained its economic importance as a shipping route in Early Medieval times according to the appearance of mintage and the spread of tollhouses. In the 8th century the Vecht still was seen as a river and as a branch of the Rhine. At that time the Vecht river discharged into a stretch of water that was named Almeer and was characterised as stagnant. The Almeer is regarded as the successor of Lake Flevo, mentioned by classical authors. Since this body of water is indicated asstagnum, it is unlikely that the water level in the southern part of the Almeer was affected by the Vlie tidal inlet in the north at that time. At the end of the 10th century the Almeer already had substantial dimensions. The building of dikes on the southern forelands of the Zuiderzee and the IJ-Lake started at least about 1200 AD. At the beginning of the timeline, settlement was limited to the natural levees of the river Vecht and its distributaries. The reclamation of the vast peatlands on both sides of the river started around the middle of the 11th century. The opening up of new areas for agriculture and settlement was accompanied by a transformation of the social fabric. In association with the pattern of land division historical information is used to indicate some of the changes that occurred in the Vecht area during that period. The drive to further intensify land use resulted in 1122 AD in the decision to build a dike on the northern bank of the Lower Rhine, since the Vecht is a blind arm of the river Rhine.
WEATHERING THE STORM: LEGALITY AND LEGAL IMPLICATIONS OF THE SAUDI-LED MILITARY INTERVENTION IN YEMEN
Authors: Ruys Tom , Ferro Luca 
Published: January 2016

AbstractOn 26 March 2015, a Saudi-led coalition launched ‘Operation Decisive Storm’ on the territory of the Republic of Yemen following a request by that country's beleaguered government. Although it received no prior fiat from the UN Security Council and took place amidst a civil war, the intervention met with approval from numerous States, with only few critical sounds. Closer scrutiny nonetheless reveals that the self-defence justification, which is primarily relied upon, does not provide a convincing legal basis for the operation. Moreover, the intervention is problematical from the perspective of the intervention by invitation doctrine and undeniably exposes its indeterminacy and proneness to abuse.
ADDRESSING ENVIRONMENTAL CONCERNS THROUGH TRADE: A CASE FOR EXTRATERRITORIALITY?
Authors: Cooreman Barbara 
Published: January 2016

AbstractIn the absence of stringent and coordinated international action, States might seek alternatives to promote environmental protection unilaterally. Trade measures may be tools to promote environmental protection in other countries through the means of trade restrictions based on the process and production methods of a good (PPMs), but can they be used to protect global environmental concerns? PPMs are considered to be controversial because of their extraterritorial character. Inspired by other fields of law where an extraterritorial application of laws is accepted, such as competition law and international human rights law, this paper proposes a systematic approach to assess the acceptability of extraterritorial trade measures with an environmental objective within the scope of the general exceptions of the GATT. This contribution purports to answer whether the WTO forms a stumbling block for States to address global environmental concerns through trade.
Freeze, Flight, Fight, Fright, Faint: Adaptationist Perspectives on the Acute Stress Response Spectrum
Authors: Bracha H. Stefan 
Published: January 2016

ABSTRACTThis article reviews the existing evolutionary perspectives on the acute stress response habitual faintness and blood-injection-injury type-specific phobia (BIITS phobia). In this article, an alternative evolutionary perspective, based on recent advances in evolutionary psychology, is proposed. Specifically, that fear–induced faintness (eg, fainting following the sight of a syringe, blood, or following a trivial skin injury) is a distinctHomo sapiens-specific extreme-stress survival response to an inescapable threat. The article suggests that faintness evolved in response to middle paleolithic intra-group and inter-group violence (of con-specifics) rather than as a pan-mammalian defense response, as is presently assumed. Based on recent literature, freeze, flight, fight, fright, faint provides a more complete description of the human acute stress response sequence than current descriptions. Faintness, one of three primary physiological reactions involved in BIITS phobia, is extremely rare in other phobias. Since heritability estimates are higher for faintness than for fears or phobias, the author suggests that trait-faintness may be a useful complement to trait-anxiety as an endophenotype in research on the human fear circuitry. Some implications for the forthcomingDiagnostic and Statistical Manual of Mental Disorders, Fifth Editionas well as for clinical, health services, and transcriptomic research are briefly discussed.
The hydrogen-bond network of water supports propagating optical phonon-like modes
Authors: Elton Daniel C. , Fernández-Serra Marivi 
Published: January 2016

AbstractThe local structure of liquid water as a function of temperature is a source of intense research. This structure is intimately linked to the dynamics of water molecules, which can be measured using Raman and infrared spectroscopies. The assignment of spectral peaks depends on whether they are collective modes or single-molecule motions. Vibrational modes in liquids are usually considered to be associated to the motions of single molecules or small clusters. Using molecular dynamics simulations, here we find dispersive optical phonon-like modes in the librational and OH-stretching bands. We argue that on subpicosecond time scales these modes propagate through water’s hydrogen-bond network over distances of up to 2 nm. In the long wavelength limit these optical modes exhibit longitudinal–transverse splitting, indicating the presence of coherent long-range dipole–dipole interactions, as in ice. Our results indicate the dynamics of liquid water have more similarities to ice than previously thought.
Controlling Gaussian and mean curvatures at microscale by sublimation and condensation of smectic liquid crystals
Authors: Kim Dae Seok , Cha Yun Jeong , Kim Mun Ho , Lavrentovich Oleg D. , Yoon Dong Ki 
Published: January 2016

AbstractSoft materials with layered structure such as membranes, block copolymers and smectics exhibit intriguing morphologies with nontrivial curvatures. Here, we report restructuring the Gaussian and mean curvatures of smectic A films with free surface in the process of sintering, that is, reshaping at elevated temperatures. The pattern of alternating patches of negative, zero and positive mean curvature of the air–smectic interface has a profound effect on the rate of sublimation. As a result of sublimation, condensation and restructuring, initially equilibrium smectic films with negative and zero Gaussian curvature are transformed into structures with pronounced positive Gaussian curvature of layers packing, which are rare in the samples obtained by cooling from the isotropic melt. The observed relationship between the curvatures, bulk elastic behaviour and interfacial geometries in sintering of smectic liquid crystals might pave the way for new approaches to control soft morphologies at micron and submicron scales.
Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer
Authors: Kamino H , Nakamura Y , Tsuneki M , Sano H , Miyamoto Y , Kitamura N , Futamura M , Kanai Y , Taniguchi H , Shida D , Kanemitsu Y , Moriya Y , Yoshida K , Arakawa H 
Published: January 2016

AbstractMieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria. BNIP3 and NIX are critical mediators for the Mieap-regulated mitochondrial quality control. Mieap suppresses murine intestinal tumor via its mitochondrial quality control function. To explore the role of the Mieap-regulated mitochondria quality control function in colorectal cancer patients, we examined the statuses of p53, Mieap, BNIP3 and NIX in 57 primary colorectal cancer tissues. Promoter methylation of the Mieap and BNIP3 genes was found in 9% and 47% of colorectal cancer cases, respectively, whereas p53 mutation was found in more than 50% of colorectal cancer tissues lacking methylation of the Mieap and BNIP3 promoters, implying that the p53/Mieap/BNIP3-regulated mitochondria quality control pathway is inactivated in more than 70% of colorectal cancer patients. In LS174T colorectal cancer cells, hypoxia activated the Mieap-regulated mitochondria quality control function. Knockdown of p53, Mieap or BNIP3 in LS174T cells severely impaired the hypoxia-activated function, leading to the accumulation of unhealthy mitochondria and increase of mitochondrial reactive oxygen species generation. The mitochondrial reactive oxygen species generated by unhealthy mitochondria in the p53/Mieap/BNIP3-deficient cells remarkably enhanced cancer cell migration and invasion under hypoxic condition. These results suggest that the Mieap-regulated mitochondria quality control has a critical role in colorectal cancer suppression in the in vivo hypoxic tumor microenvironment.
Plasmon-photon conversion to near-infrared emission from Yb3+: (Au/Ag-nanoparticles) in tungsten-tellurite glasses
Authors: Rivera V. A. G. , Ledemi Yannick , Pereira-da-Silva Marcelo A. , Messaddeq Younes , Marega Jr Euclydes 
Published: January 2016

AbstractThis manuscript reports on the interaction between 2F5/2→2F7/2 radiative transition from Yb3+ ions and localized surface plasmon resonance (from gold/silver nanoparticles) in a tungsten-tellurite glass. Such an interaction, similar to the down-conversion process, results in the Yb3+ emission in the near-infrared region via resonant and non-resonant energy transfers. We associated such effects with the dynamic coupling described by the variations generated by the Hamiltonian HDC in either the oscillator strength, or the local crystal field, i.e. the line shape changes in the emission band. Here, the Yb3+ ions emission is achieved through plasmon-photon coupling, observable as an enhancement or quenching in the luminescence spectra. Metallic nanoparticles have light-collecting capability in the visible spectrum and can accumulate almost all the photon energy on a nanoscale, which enable the excitation and emission of the Yb3+ ions in the near-infrared region. This plasmon-photon conversion was evaluated from the cavity’s quality factor (Q) and the coupling (g) between the nanoparticles and the Yb3+ ions. We have found samples of low-quality cavities and strong coupling between the nanoparticles and the Yb3+ ions. Our research can be extended towards the understanding of new plasmon-photon converters obtained from interactions between rare-earth ions and localized surface plasmon resonance.
Sex differences in behavioural and neural responsiveness to mate calls in a parrot
Authors: Eda-Fujiwara Hiroko , Satoh Ryohei , Hata Yuka , Yamasaki Marika , Watanabe Aiko , Zandbergen Matthijs A. , Okamoto Yasuharu , Miyamoto Takenori , Bolhuis Johan J. 
Published: January 2016

AbstractVocalisation in songbirds and parrots has become a prominent model system for speech and language in humans. We investigated possible sex differences in behavioural and neural responsiveness to mate calls in the budgerigar, a vocally-learning parrot. Males and females were paired for 5 weeks and then separated, after which we measured vocal responsiveness to playback calls (a call of their mate versus a call of an unfamiliar conspecific). Both sexes learned to recognise mate calls during the pairing period. In males, but not females, mate calls evoked significantly fewer vocal responses than unfamiliar calls at one month after separation. Furthermore, in females, there was significantly greater molecular neuronal activation in response to mate calls compared to silence in the caudomedial mesopallium (CMM), a higher-order auditory region, in both brain hemispheres. In males, we found right-sided dominance of molecular neuronal activation in response to mate calls in the CMM. This is the first evidence suggesting sex differences in functional asymmetry of brain regions related to recognition of learned vocalisation in birds. Thus, sex differences related to recognition of learned vocalisations may be found at the behavioural and neural levels in avian vocal learners as it is in humans.
PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis
Authors: Huang Jeffrey Y. , Wang Kang , Vermehren-Schmaedick Anke , Adelman John P. , Cohen Michael S. 
Published: January 2016

AbstractMono-ADP-ribosylation (MARylation) of mammalian proteins was first described as a post-translational modification catalyzed by bacterial toxins. It is now known that endogenous MARylation occurs in mammalian cells and is catalyzed by 11 members of the poly-ADP-ribose polymerase (PARP) family of proteins (17 in humans). The physiological roles of these PARPs remain largely unknown. Here we demonstrate that PARP6, a neuronally enriched PARP that catalyzes MARylation, regulates hippocampal dendrite morphogenesis, a process that is critical for proper neural circuit formation during development. Knockdown of PARP6 significantly decreased dendritic complexity in embryonic rat hippocampal neurons in culture and in vivo. Expression of wild-type PARP6 increased dendritic complexity; conversely, expression of a catalytically inactive PARP6 mutant, or a cysteine-rich domain deletion mutant that has significantly reduced catalytic activity, decreased dendritic complexity. The identification of PARP6 as a regulator of dendrite morphogenesis supports a role for MARylation in neurons during development.
Photoluminescence and electronic transitions in cubic silicon nitride
Authors: Museur Luc , Zerr Andreas , Kanaev Andrei 
Published: January 2016

AbstractA spectroscopic study of cubic silicon nitride (γ-Si3N4) at cryogenic temperatures of 8 K in the near IR - VUV range of spectra with synchrotron radiation excitation provided the first experimental evidence of direct electronic transitions in this material. The observed photoluminescence (PL) bands were assigned to excitons and excited "Equation missing" and "Equation missing" centers formed after the electron capture by neutral structural defects. The excitons are weakly quenched on neutral "Equation missing" and strongly on charged "Equation missing" defects. The fundamental band-gap energy of 5.05 ± 0.05 eV and strong free exciton binding energy ~0.65 eV were determined. The latter value suggests a high efficiency of the electric power transformation in light in defect-free crystals. Combined with a very high hardness and exceptional thermal stability in air, our results indicate that γ-Si3N4 has a potential for fabrication of robust and efficient photonic emitters.