bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maintenance management system (MMS) to support facilities management at Malaysian polytechnic
Authors: Ismail Zul-Atfi 
Published: August 2017

Purpose
Conventional methods practiced by the Development and Facilities Management Unit (UPPF) have faced issues due to management deficiencies and incompetent staff members who were unable to handle facilities management assessment processes at Malaysian Polytechnics. The paper aims to discuss this issue.

Design/methodology/approach
The prime objective of this paper is to improve the conventional methods which tend to be both cumbersome and ineffective in the UPPF Maintenance Management Systems (MMSs) at Malaysian Polytechnics. Primary data were gathered through interviews to develop the proposed system. Eight Polytechnics were selected based on major problems arising from using conventional methods. A comparison was then conducted to investigate the maintenance management practices at each Polytechnic. There are around 32 Polytechnics in Malaysia and most are using conventional methods.

Findings
The major conclusion drawn from the interview results was that comprehensive MMSs are lacking, specifically those that integrate operation and maintenance (O&M) processes of facilities management and software programming that provides guidelines for decision-making processes. The interview results also revealed irregularities within the Malaysian Polytechnics’ maintenance management database. This paper explores the concepts of Electronic Form Defect Assessment (E-Form Defect Assessment), relational databases and online customer complaints to adapt their role as dynamic maintenance management tools.

Originality/value
The paper concludes that the developed system is able to accommodate recording of data, such as complaints and specific items needed for maintenance, through the internet and intranet. MMSs potentially transform facilities management O&M processes into one of the most sophisticated technologies by providing access to all information published by each Malaysian Polytechnic institution. This technology was established in order to foster financial cooperation with the idea being that Polytechnics which compete with one another become financially interdependent with the goal of promoting successful facilities management in the construction of new facilities and infrastructure.
Risk factors for multidrug‐resistant Gram‐negative infection in burn patients
Authors: Vickers Mark L. , Dulhunty Joel M. , Ballard Emma , Chapman Paul , Muller Michael , Roberts Jason A. , Cotta Menino O. 
Published: August 2017

BackgroundInfection with multidrug‐resistant (MDR) Gram‐negative organisms leads to poorer outcomes in the critically ill burn patient. The aim of this study was to identify the risk factors for MDR Gram‐negative pathogen infection in critically ill burn patients admitted to a major tertiary referral intensive care unit (ICU) in Australia.MethodsA retrospective case–control study of all adult burn patients admitted over a 7‐year period was conducted. Twenty‐one cases that cultured an MDR Gram‐negative organism were matched with 21 controls of similar age, gender, burn size and ICU stay. Multivariable conditional logistic regression was used to individually assess risk factors after adjusting for Acute Burn Severity Index. Adjusted odds ratios (ORs) were reported. P‐values < 0.25 were considered as potentially important risk factors.ResultsFactors increasing the risk of MDR Gram‐negative infection included superficial partial thickness burn size (OR: 1.08; 95% confidence interval (CI): 1.01–1.16; P‐value: 0.034), prior meropenem exposure (OR: 10.39; 95% CI: 0.96–112.00; P‐value: 0.054), Gram‐negative colonization on admission (OR: 9.23; 95% CI: 0.65–130.15; P‐value: 0.10) and escharotomy (OR: 2.66; 95% CI: 0.52–13.65; P‐value: 0.24). For cases, mean age was 41 (SD: 13) years, mean total body surface area burned was 47% (SD: 18) and mean days in ICU until MDR specimen collection was 17 (SD: 10) days.ConclusionPrior meropenem exposure, Gram‐negative colonization on admission, escharotomy and superficial partial thickness burn size may be potentially important factors for increasing the risk of MDR Gram‐negative infection in the critically ill burn patient.
The AB Portable Driver Generates Higher Drive‐Line Pressures Possibly Leading to Accelerated Hemolysis
Authors: Goda Motohiko , Yabu Naoto , Tominaga Norihisa , Machida Daisuke , Isomatsu Yukihisa , Suzuki Shinichi , Nitta Manabu , Komura Naohiro , Nakayama Naoki , Kiyokuni Masayoshi , Sugano Teruyasu , Masuda Munetaka 
Published: August 2017

AbstractThe AB5000 Circulatory Support System is paracorporeal pulsatile ventricular assist device. The AB Portable Driver is a portable console for this system. We experienced two cases with accelerated hemolysis while receiving support by the AB Portable Driver. The purpose of this study was to clarify the mechanical differences associated with the hemolysis between the AB5000 console and the AB Portable Driver. The mock circulatory system modeled by an AB5000 ventricle and a blood sampling bag of vinyl chloride was run with an AB5000 console or AB Portable Driver. The peak drive‐line pressure, the mean arterial cannula pressure and the pumping rate of the VAD were recorded. The AB5000 console generated a peak drive‐line pressure of 280–300 mm Hg in LVAD mode and 210–220 mm Hg in RVAD mode, approximately 100 mm Hg lower than officially documented. In contrast, the AB Portable Driver generated pressures of 310–330 mm Hg in LVAD mode and 230–250 mm Hg in RVAD mode, 65–95 mm Hg higher than officially documented. The AB Portable Driver console generates higher drive‐line pressures than the AB5000 console, possibly explaining the accelerated hemolysis.
Long‐term evaluation of osteotome sinus floor elevation and simultaneous placement of implants without bone grafts: 10‐Year radiographic and clinical follow‐up
Authors: Caban Janusz , Fermergård Robert , Abtahi Jahan 
Published: August 2017

AbstractBackgroundInsertion of an implant in the edentulous posterior maxilla is a challenging procedure because of poor bone quality and increased pneumatization of the maxillary sinus after tooth extraction. To increase the amount of bone, several surgical bone grafting techniques have been used―with considerable morbidity for patients. Osteotome sinus floor elevation (OSFE) is a less invasive technique. The clinical and radiographic outcome of 53 implants placed with this technique without bone graft has been reported previously.PurposeHere we report the clinical and radiographic findings after 10 years of implant load bearing.Material and methodsIn a retrospective study, 34 Astra implants in 25 patients were subjected to 10‐year follow‐up radiologically and clinically. Each patient received 1 or 2 conical Astra implants. The level of the marginal bone and the height of the residual peri‐implant alveolar bone (RPAB) for each implant were measured from digital intra‐oral radiographs.ResultsTwo implants in edentulous patients were lost at the 1‐year follow‐up, and 1 more at the 3‐year examination. There was no loss between 3‐year and 10‐year follow‐up. At 10‐year follow‐up 36 implants were included. Implants used in single‐tooth replacements and in partially edentulous cases had a 100% survival rate. The mean marginal bone loss was 0.6 ± 0.8 mm. The bone height at the time of implant insertion ranged from 1.8 to 6.9 mm, with a mean value of 4.3 ± 1.0 mm. At 10‐year follow‐up the mean gain in bone at the implant sites for all implants was 2.6 ± 1.2 mm.ConclusionsThe OSFE technique is a reliable method for rehabilitation of patients with atrophied posterior maxilla. However, the success of this method is associated with the amount of the residual bone. In the present study, this surgical approach without bone graft showed reliable long‐term results with Astra implants.
Movement, distribution and marine reserve use by an endangered migratory giant
Authors: Reynolds Samantha D. , Norman Bradley M. , Beger Maria , Franklin Craig E. , Dwyer Ross G. 
Published: August 2017

AbstractAimUnderstanding the spatial and temporal variation in the distribution of migratory species is critical for management and conservation efforts. However, challenges in observing mobile marine species throughout their migratory pathways can impede the identification of critical habitat, linkages between these habitats and threat‐mitigation strategies. This study aimed to gain insight into the long‐term residency and movement patterns of the whale shark (Rhincodon typus) and to reveal important habitat in the context of R. typus usage of existing Marine Protected Areas (MPAs).LocationSouth‐eastern Indian Ocean.MethodsSatellite telemetry was used to remotely track the long‐term movements of 29 R. typus, and to quantify shark usage of the existing MPA network. From the tracking data and environmental predictors, nonlinear models were developed to predict suitable R. typus habitat throughout the south‐eastern Indian Ocean.ResultsThis study includes the first documented complete return migrations by R. typus to Ningaloo Marine Park, which was found to be an important area for R. typus all year‐round. We found that while existing MPAs along Australia's west coast do afford some protection to R. typus, telemetry‐based habitat models revealed large areas of suitable habitat not currently protected, particularly along the Western Australian coast, in the Timor Sea, and in Indonesian and international waters.Main conclusionsAnimal‐borne telemetric devices allowed the gathering of long‐term spatial information from the elusive and highly mobile R. typus, revealing the spatial scale of their migration in the south‐eastern Indian Ocean. Suitable habitat was predicted to occur inside conservation areas, but our findings indicate that the current MPA network may not sufficiently protect R. typus throughout the year. We suggest that telemetry‐based habitat models can be an important tool to inform conservation planning and spatial management efforts for migratory species.
Does artificial light pollution impair problem‐solving success in peafowl?
Authors: Yorzinski Jessica L. , Ordonez Kimberly A. , Chema Kailey T. 
Published: August 2017

AbstractBehavioral innovations allow animals to adjust their behavior to solve novel problems. While innovative behavior can be important for animals living in new environments, anthropogenic pollution may limit their ability to adapt by impairing cognition or motivation. In particular, exposure to light pollution at night can cause sleep deprivation and may, therefore, hinder innovative behavior. To test this hypothesis, we examined experimentally whether exposure to acute light pollution impacts problem‐solving success in peafowl (Pavo cristatus). After peafowl were exposed to artificial light pollution for one night, they were presented with a problem‐solving task in which they could extract food by piercing the lid of an unfamiliar food bowl. Their problem‐solving success was unrelated to short‐term light pollution exposure. Other factors, including persistence, sex of the bird, and moon illumination, influenced their success in solving the task. The results suggest that short‐term exposure to light pollution does not limit behavioral innovation, but long‐term studies are necessary to further probe this question.
Adaptive parasitic manipulation as exemplified by acanthocephalans
Authors: Bakker Theo C. M. , Frommen Joachim G. , Thünken Timo 
Published: August 2017

AbstractParasites with complex life cycles often change intermediate host traits in order to enhance their transmission to the next host. Acanthocephalans are excellent examples of such parasitic manipulation. Here, we summarise evidence for adaptive parasitic manipulation in this group, provide a comprehensive overview of intermediate host traits affected by these parasites and discuss critical items for parasitic manipulation such as avoidance of infected prey by target hosts and transmission to dead‐end hosts.
Location of white matter changes and response to donepezil in patients with Alzheimer's disease: A retrospective and observational study
Authors: Wu Meng‐Ni , Kao Yi‐Hui , Chou Ping‐Song , Lin Tzu‐Chao , Kao Lin‐Li , Yang Yuan‐Han 
Published: August 2017

AimThe response to donepezil in patients with Alzheimer's disease varies, and it is important to identify the potential responder before therapy. Cerebral white matter changes (WMC) are frequently observed in older patients, and the effect of WMC on therapeutic response remains controversial. The present study aimed to investigate the relationships between the location of WMC, severe WMC and the response to donepezil.MethodsAmong 418 patients with Alzheimer's disease receiving donepezil, 196 patients were eligible for analysis. Five brain areas on each side were analyzed using computed tomography scans and the Age‐Related White Matter Changes Rating Scale before therapy. The Cognitive Abilities Screening Instrument was used annually. Patients were defined as responders if their baseline Cognitive Abilities Screening Instrument score minus their follow‐up Cognitive Abilities Screening Instrument score was ≤0.ResultsThere was no significant difference in demographic data between responder and non‐responder groups. Patients in the responder group had significantly less involvement of WMC in the frontal area (P = 0.0213) and nearly a trend for less involvement of WMC in the basal ganglia (P = 0.1103). After adjustment for age, sex, education, polymorphism of apolipoprotein E, hypertension and diabetes, WMC in the frontal area (OR 0.446, P = 0.0139) and basal ganglia (OR 0.243, P = 0.0380) were significantly associated with a reduced therapeutic response.ConclusionsPatients with WMC in the frontal area and basal ganglia had significant decreases in their therapeutic response to donepezil. The location of WMC, independent of their severity, might be associated with the therapeutic response in patient with Alzheimer's disease. Geriatr Gerontol Int 2018; 18: 123–129.
Various pathophysiological states of acute symptomatic seizures immediately after ischemic stroke, namely “onset seizures,” shown by complementary use of peri‐ictal magnetic resonance imaging and electroencephalography
Authors: Murao Kei , Morioka Takato , Shimogawa Takafumi , Furuta Yoshihiko , Haga Sei , Sakata Ayumi , Arihiro Shoji , Arakawa Shuji 
Published: August 2017

AbstractBackground“Onset seizures” are acute symptomatic seizures occurring within 24 h after the onset of ischemic stroke, and their pathophysiological states are unknown. Electroencephalography is commonly used to diagnose epileptic activities; however, it is limited for use with acute stroke. Magnetic resonance imaging, including diffusion‐weighted imaging and perfusion imaging with arterial spin labeling, are applied mainly in an emergency. Ictal hyperperfusion on arterial spin labeling and cortical hyperintensity of cytotoxic edema on diffusion‐weighted imaging, peri‐ictally, can be obtained from an epileptically activated cortex.AimWe aimed to show pathophysiological states of onset seizures by complementary use of peri‐ictal magnetic resonance imaging and electroencephalography.MethodsFour patients diagnosed as onset seizures underwent an initial magnetic resonance imaging and subsequent electroencephalography.ResultsIn case 1, having persistent non‐convulsive status epilepticus after control of onset seizures, ictal magnetic resonance imaging and electroencephalography findings clearly showed the topographical relationship between the acute atherothrombotic infarction and the peri‐infarction activated cortex. In case 2, with multiple embolic strokes in the bifrontal lobes, prolonged arterial spin labeling hyper signals were observed in the perirolandic area of the right leg; cortical hyperintensity on diffusion‐weighted imaging and paroxysmal activities on electroencephalography were not shown. In cases 3 and 4, postictal hypoperfusion was shown in the large extent involving the multiple embolic infarctions. Because the epileptic cortex was located in the convexity, electroencephalography clearly showed inter‐ictal paroxysms in case 3, and localized slow wave in case 4.ConclusionThe present study shows that the complementary use of peri‐ictal arterial spin labeling/diffusion‐weighted imaging and electroencephalography potentially offers the ability to document the various pathophysiological states of onset seizure.
Serious hyponatremia induced by a combination of angiotensin II receptor blocker and thiazide caused deterioration of cognitive functions and psychological symptoms in an elderly Alzheimer's disease patient
Authors: Sato Kota , Takemoto Mami , Hishikawa Nozomi , Ohta Yasuyuki , Yamashita Toru , Abe Koji 
Published: August 2017

AbstractAs the number of elderly people increases, Alzheimer's disease and hypertension have become more common. This is an important case report that shows severe hyponatremia induced by a combination of angiotensin II receptor blocker and thiazide, causing the deterioration of cognitive functions in an elderly patient. In rapidly aging societies around the world, more attention should be paid to hyponatremia under combination therapy of angiotensin II receptor blocker plus thiazide to assist elderly patients.
Assessment and implications of social withdrawal in early childhood: A first look at social avoidance
Authors: Coplan Robert J. , Ooi Laura L. , Xiao Bowen , Rose‐Krasnor Linda 
Published: August 2017

AbstractThe goals of the present research were to: (a) develop and provide preliminary validation of a parent‐rated measure of social avoidance in early childhood; and (b) to evaluate a conceptual model of the direct and indirect links among young children's social withdrawal (shyness, unsociability, social avoidance), peer problems, and indices of internalizing problems (social anxiety, depression). Participants were N = 564 children (272 boys, 292 girls; Mage = 67.29 mos, SD = 11.70) attending kindergarten and Grade 1 classes in public schools in southeastern Ontario, Canada. A new subscale assessing social avoidance was added to an existing parent‐rated measure of children's social withdrawal. Indices of children's socioemotional functioning were provided by parents and teachers. Among the results, the revised measure of multiple forms of social withdrawal demonstrated good psychometric properties, moderate stability 16 months later, and evidence of validity. Shyness, unsociability, and social avoidance also displayed differential patterns of associations with indices of children's socioemotional functioning. Results are discussed in terms of the assessment and implications of different forms of social withdrawal in early childhood.
AN EXPONENTIALLY WEIGHTED MOVING AVERAGE METHOD WITH DESIGNED INPUT DATA ASSIGNMENTS FOR FORECASTING LIME PRICES IN THAILAND
Authors: Booranawong Thitima , Booranawong Apidet 
Published: August 2017

In this paper, the Exponentially Weighted Moving Average (EWMA) method with designed input data assignments (i.e. the proposed method) is presented to forecast lime prices in Thailand during January 2016 to December 2016. The lime prices from January 2011 to December 2015 as the input data are gathered from the website’s database of Simummuang market, which is one of the big markets in Thailand. The novelty of our paper is that although the performance of the EWMA method significantly decreases when applying to forecast data which show trend and seasonality behaviors and the EWMA method is used for short-range forecasting (i.e. usually one month into the future), the proposed method can properly handle such mentioned problems. For this purpose, to forecast lime prices, five different input data are intently defined before assigned to the EWMA method: a) the monthly data of the year 2015 (i.e. the recent year data), b) the average monthly data of the year 2011 to 2015, c) the median of the monthly data of the year 2011 to 2015, d) the monthly data of the year 2011 to 2015 after applying the linear weighting factor, where the higher weight value is applied to the recent data, and e) the average monthly data of the year 2011 to 2015 after applying the exponential weighting factor, where the higher weight is also applied to the recent data. These designed input data are used as agents of the raw data. Our study reveals that using the input data b) with the EWMA method to forecast lime prices during January 2016 to September 2016 gives the smallest forecasting error measured by the Mean Absolute Percentage Error (MAPE). Forecasted lime prices of October 2016 to December 2016 are also provided. Additionally, we demonstrate that the proposed method works well compared with the Double Exponentially Weighted Moving Average (DEWMA), the Multiplicative Holt-Winters (MHW), and the Additive Holt-Winters (AHW) methods, which are suitably used for forecasting data with the trend and the seasonality.
Cardiolipin Synthesis and Outer Membrane Localization Are Required for
Shigella flexneri
Virulence
Authors: Rossi Rachael M. , Yum Lauren , Agaisse Hervé , Payne Shelley M. 
Published: August 2017

ABSTRACT

Cardiolipin, an anionic phospholipid that resides at the poles of the inner and outer membranes, is synthesized primarily by the putative cardiolipin synthase ClsA in
Shigella flexneri
. An
S. flexneri clsA
mutant had no cardiolipin detected within its membrane, grew normally
in vitro
, and invaded cultured epithelial cells, but it failed to form plaques in epithelial cell monolayers, indicating that cardiolipin is required for virulence. The
clsA
mutant was initially motile within the host cell cytoplasm but formed filaments and lost motility during replication and failed to spread efficiently to neighboring cells. Mutation of
pbgA
, which encodes the transporter for cardiolipin from the inner membrane to the outer membrane, also resulted in loss of plaque formation. The
S. flexneri pbgA
mutant had normal levels of cardiolipin in the inner membrane, but no cardiolipin was detected in the outer membrane. The
pbgA
mutant invaded and replicated normally within cultured epithelial cells but failed to localize the actin polymerization protein IcsA properly on the bacterial surface and was unable to spread to neighboring cells. The
clsA
mutant, but not the
pbgA
mutant, had increased phosphatidylglycerol in the outer membrane. This appeared to compensate partially for the loss of cardiolipin in the outer membrane, allowing some IcsA localization in the outer membrane of the
clsA
mutant. We propose a dual function for cardiolipin in
S. flexneri
pathogenesis. In the inner membrane, cardiolipin is essential for proper cell division during intracellular growth. In the outer membrane, cardiolipin facilitates proper presentation of IcsA on the bacterial surface.

IMPORTANCE
The human pathogen
Shigella flexneri
causes bacterial dysentery by invading colonic epithelial cells, rapidly multiplying within their cytoplasm, and then spreading intercellularly to neighboring cells. Worldwide,
Shigella
spp. infect hundreds of millions of people annually, with fatality rates up to 15%. Antibiotic treatment of
Shigella
infections is compromised by increasing antibiotic resistance, and there is no approved vaccine to prevent future infections. This has created a growing need to understand
Shigella
pathogenesis and identify new targets for antimicrobial therapeutics. Here we show a previously unknown role of phospholipids in
S. flexneri
pathogenesis. We demonstrate that cardiolipin is required in the outer membrane for proper surface localization of IcsA and in the inner membrane for cell division during growth in the host cell cytoplasm.