bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marija Crnobori’s autobiographical prose: a diary of construction of a theatre
Authors: Grubišić Pulišelić Eldi 
Published: July 2017

Summary
By analysing the diary entitled Pamet, širom otvorene oči i – ljubav. Dnevnik izgradnje Jugoslovenskog dramskog pozorišta (‘Intellect – eyes wide open and – love. Diary of the construction of the Yugoslav Drama Theatre’) by Marija Crnobori, we reach interesting discoveries linked to the socio-political, cultural and historical context of its inception. However, above all, we gain insight into the internal life of the author at a certain period in her life. The diary which Crnobori started writing after a fire totally destroyed her theatre, became a framework within which she began to build her own world; she thinks about the past, present and future, about important people who have professionally and emotionally marked her life and about people passing by, about “a little life” which was slowly reaching its end. In this autobiographical text by Marija Crnobori we notice three different narrative layers which are mutually intertwined providing the reader with an insight into the complex world of a diary subject. The diary has become a space to construct her multi-fold identity from a lonely pensioner to an established actress, from a family woman and friend to a writer and social chronicler.
Overexpression of c-Myc enhances recombinant protein production in High Five cells after baculovirus infection
Authors: Ju Xiaoli , Ren Meijia , Chen Keping , Wang Qiang 
Published: July 2017

Abstract
Due to their numerous advantages, baculovirus expression vector systems (BEVS) have been widely used to express recombinant proteins for different purposes. Different strategies have been adopted to increase recombinant protein production. In this study, we transiently or stably expressed mouse c-Myc in High Five cells using a commercial pIB/V5 vector. Under the control of the OpIE2 promoter, this vector could enhance recombinant protein production. We found that transient expression of c-Myc in High Five cells improved recombinant protein production. Furthermore, we established two stable cell lines, High Five-c-Myc #1 and High Five-c-Myc #2, that stably expressed mouse c-Myc. We further found that the expression level of the recombinant protein was increased in these stable cell lines compared to control cell lines. These data indicate that overexpressing c-Myc in cells is a promising way to improve recombinant protein production in BEVS.
Normal Striatal Vesicular Acetylcholine Transporter Expression in Tourette Syndrome
Authors: Albin Roger L. , Minderovic Christine , Koeppe Robert A. 
Published: July 2017

AbstractConsiderable prior work suggests basal ganglia dysfunction in Tourette syndrome (TS). Analysis of a small number of postmortem specimens suggests deficits of some striatal interneuron populations, including striatal cholinergic interneurons. To assess the integrity of striatal cholinergic interneurons in TS, we used [18F]FEOBV positron emission tomography (PET) to quantify striatal vesicular acetylcholine transporter (VAChT) expression, a measure of cholinergic terminal density, in human TS and control subjects. We found no evidence of striatal cholinergic deficits. Discrepant imaging and postmortem analysis results may reflect agonal or postmortem changes, medication effects, or significant disease heterogeneity.
Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis
Authors: Xu Yiming , Wang Yong , Yan Siyuan , Zhou Yaqi , Yang Qiuhua , Pan Yue , Zeng Xianqiu , An Xiaofei , Liu Zhiping , Wang Lina , Xu Jiean , Cao Yapeng , Fulton David J , Weintraub Neal L , Bagi Zsolt , Hoda Md Nasrul , Wang Xiaoling , Li Qinkai , Hong Mei , Jiang Xuejun , Boison Detlev , Weber Christian , Wu Chaodong , Huo Yuqing 
Published: July 2017

AbstractThe nucleoside adenosine is a potent regulator of vascular homeostasis, but it remains unclear how expression or function of the adenosine‐metabolizing enzyme adenosine kinase (ADK) and the intracellular adenosine levels influence angiogenesis. We show here that hypoxia lowered the expression of ADK and increased the levels of intracellular adenosine in human endothelial cells. Knockdown (KD) of ADK elevated intracellular adenosine, promoted proliferation, migration, and angiogenic sprouting in human endothelial cells. Additionally, mice deficient in endothelial ADK displayed increased angiogenesis as evidenced by the rapid development of the retinal and hindbrain vasculature, increased healing of skin wounds, and prompt recovery of arterial blood flow in the ischemic hindlimb. Mechanistically, hypomethylation of the promoters of a series of pro‐angiogenic genes, especially for VEGFR2 in ADK KD cells, was demonstrated by the Infinium methylation assay. Methylation‐specific PCR, bisulfite sequencing, and methylated DNA immunoprecipitation further confirmed hypomethylation in the promoter region of VEGFR2 in ADK‐deficient endothelial cells. Accordingly, loss or inactivation of ADK increased VEGFR2 expression and signaling in endothelial cells. Based on these findings, we propose that ADK downregulation‐induced elevation of intracellular adenosine levels in endothelial cells in the setting of hypoxia is one of the crucial intrinsic mechanisms that promote angiogenesis.
The Effectiveness of Traditional Games intervention program in the Improvement of Form One School-Age Children’s Motor Skills Related Performance Components
Authors: @ Charles Md. Alli Gipit , Abdullah Mohamad Razali , Musa Rabiu Muazu , Kosni Norlaila Azura , Musawi Maliki Ahmad Bisyri Husin 
Published: July 2017

Abstract:As children age, motor performance develops. Motor performance abilities enable children to process information in handling specific task efficiently. Although children develop motor skills in a variety of physical activities, it could be, however, easily achieved when they engage in voluntary activities in conformity with their interests. Traditional games offer the opportunity for children to play and officiate the rules without any constraint. The current study intends to explore the effectiveness of the traditional games intervention program in the improvement of form one school-age children’s motor skills related performance components. A total number of 40 form one Malaysian student [male (n=20) and female (n=20)] with age range of 12-13 selected randomly participated in the study. The quasi-experiment method was applied in the study and experiment group (n=40) went through traditional games intervention which consisted of performing selected traditional games for 60 minutes, three times weekly for eight weeks. The pre-test (before treatment), mid-test (week fourth) and post-test (week eight) data were collected and analysed using MANOVA repeated measure. The results indicate a significant improvement of motor performance through traditional games intervention [F (8, 29) = 1704.16, p < .05]. Follow-up tests also show that the traditional games intervention is a factor [F(12,105) =1.99, p < .05] to agility [F(3,36) = .50, p >.05], reaction time [F(3,36) = .51, p >.05], speed [F(3,36) = 3.64, p <.05] and balance [F(3,36) = .02, p > .05]. There is sufficient evidence to conclude that Malaysian based traditional games are effective in improving motor abilities of school-age children.
Pre-participation evaluation of Malaysian university athletes – the importance of cardiovascular screening
Authors: Lim Zhuang Li , Mokhtar Abdul Halim , Jaffar Muhammad Rahmani 
Published: July 2017

Background: Sudden cardiac arrest and death (SCA/D) remains the leading cause of mortality among athletes. Contemporary standards of identifying normal physiological cardiac adaptations and remodeling from regular athletic training based on certain ECG morphology have been clearly defined by the ‘Seattle Criteria’ in 2012, with an updated ‘International Consensus’ in 2017. In heterogenous Asia, regional SCA/D preponderance data is still lacking. This study aims to report on the detection of potentially dangerous cardiovascular conditions in Malaysian university athletes via pre-participation evaluation.Methods: 176 Malaysian athletes competing in the 18th ASEAN University Games 2016 were requested to attend a centralised pre-participation evaluation (PPE) prior to the games. The PPE included history, physical examination and a resting ECG. Participating sports and the corresponding number of athletes were athletics (40), basketball (26), football (24), silat (16), rugby (14), badminton (14), table tennis (12), shooting (12), fencing (10) and petanque (8).Results: 113 athletes (64.2%) attended and completed the PPE. The highest percentages of athletes screened were from shooting, fencing and petanque (100% respectively), whilst the lowest were from the basketball team (23.1%). Three abnormal ECGs were identified: a multiple premature ventricular contractions, an atrial tachyarrhythmia and a ventricular pre-excitation. These three athletes were referred for subsequent investigations of which two were allowed to return to play. The latter athlete was diagnosed with Wolff-Parkinson-White syndrome and was advised against competing until definitive management was instituted. Conclusion: Only a fair number of Malaysian university athletes completed the medical screening, and hence are possibly unaware of the importance of PPE. Despite our small sample size, we picked up three cases requiring further investigation and interventional studies. No screening program provides absolute protection against death. Thus, more evidence-based research and constant update in best practice guidelines are vital to foster safe sports participation and ultimately reduce incidence of SCA/D in the athletic population. Athletes need to be aware and give full cooperation for PPE to ensure timely detection of high risk cardiovascular conditions especially those related to sudden death in sports.
Comparing periodised protocols for the maintenance of strength and power in resistance-trained women
Authors: Yee Kok Lian 
Published: July 2017

Purpose: The purpose of the study was to compare the effects of daily undulating periodisation (DUP) and session undulating periodisation (SUP) for maintaining strength and power over a 3-wk period in a group of resistance-trained women. DUP comprised one session each of strength and power training while DUP combined both strength and power training within each session. Both training programmes were equalised for training volume and intensity. Methods: Sixteen resistance-trained women were pre-tested for body mass, mid-arm and mid-thigh girths, one-repetition maximum (1 RM) dynamic squat (SQ) and bench press (BP), and power during countermovement jumps (CMJ) and bench press throws (BPT). The 1 RM SQ and BP data were used to assign the participants into groups for twice a week training. Results: A two-way (group x time) analysis of variance (ANOVA) with repeated measures for time found no significant changes in body mass, mid-arm girth, 1 RM BP and SQ, and BPT and CMJ power for both groups. However, significant changes in mid-thigh girth were found (F1, 13 = 5.733, p = 0.032). Pooled BP data indicated improved upper body strength (BP: F1, 13 = 6.346, p = 0.025) and decreased CMJ power (p = 0.016). Conclusions: Both DUP and SUP programmes increased upper-body strength and maintained lower-body strength adequately across a 3-wk phase probably because the participants were weaker in the upper-body and the lower-body had a reduced capacity for strength adaptations and improvements.
Multilocus sequence typing analysis of Klebsiella pneumoniae isolated from swine
Authors: Fan Yang , SM Li , Min Li 
Published: July 2017

A total of 86 strains Klebsiella pneumoniae isolated from swine were collected to analysis the molecular genetic characteristic by multilocus sequence typing (MLST). The eURST software was used to evaluate the results of MLST. The results indicated that all isolates clustered into 14 ST types(STs). ST106 (including 3 strians) and ST23 (including 2 strians) were single branch. Other 12 ST types belong to the CC258 clonal complex. This study showed that klebsiella pneumoniae isolated from swine in this region has some genetic diversity and the main types were ST258 clone complex, it may be transfered between swine and human.
The Influence of a Bifidobacterium animalis Probiotic on Gingival Health: A Randomized Controlled Clinical Trial
Authors: Kuru Bahar Eren , Laleman Isabelle , Yalnızoğlu Tuğçe , Kuru Leyla , Teughels Wim 
Published: July 2017

Background: There is growing interest in the use of probiotics in periodontal therapy; however, until now, most research has focused on lactobacilli probiotics. The aim of this study is to evaluate the effect of 4‐week use of yogurt supplemented with Bifidobacterium animalis subsp. lactis DN‐173010 versus a placebo yogurt, followed by a 5‐day non‐brushing period.Methods: Individuals were included in this single‐mask, randomized, controlled study if probing depth (PD) was ≤3 mm and attachment loss was ≤2 mm. After professional prophylaxis, they were randomized into two groups receiving yogurt containing either placebo or B. animalis for 28 days, followed by a 5‐day non‐brushing period. Outcome measures were plaque index (PI), gingival index (GI), bleeding on probing (BOP), PD, gingival crevicular fluid (GCF) volume, and total amount and concentration of interleukin (IL)‐1β in GCF. These were measured at baseline, after 28 days of study product use, and subsequently after 5 days of plaque accumulation.Results: Fifty‐one patients were analyzed. No intergroup differences could be detected before and after intake of study products. However, after plaque accumulation, significantly better results for all parameters were seen in the probiotic group compared with the control group (P <0.001): lower PI and GI, less BOP, less increase in GCF volume, and lower IL‐1β total amount/concentration.Conclusion: The use of a probiotic yogurt supplemented with B. animalis can have a positive effect on plaque accumulation and gingival inflammatory parameters after refraining from oral hygiene practices.
A educação escolar primária na Primeira República (1889-1929)
Authors: Rossi Ednéia Regina 
Published: July 2017

Este artigo se propõe a refletir sobre a relação entre os projetos educacionais da Primeira República no Brasil (1899-1929) e o pensamento moderno e iluminista. A Primeira República se caracterizou pela implantação de reformas de ensino em diferentes estados brasileiros. Esses projetos, embora possuíssem particularidades de estado para estado, em termos gerais, partilharam do ideal de normalizar, profissionalizar e sistematizar a escolarização das camadas populares. Em termos de finalidades formativas, a escola possuía objetivos explícitos de aculturação e socialização. Por meio dela, por exemplo, as crianças se tornariam homens e mulheres com sentimentos nacionais e subjugados à autoridade não pelo temor, mas pela razão que julga e decide. Esse novo mecanismo de controle, feito de racionalidade, a ser desenvolvido pela escola, pode ser observado nas intenções estruturadoras da escola primária e nos conhecimentos por ela transmitidos. Ao mesmo tempo, esses projetos intencionavam homogeneizar costumes, hábitos e quereres, delineando um sistema de ensino dirigido e controlado, de forma a produzir a unificação da nação brasileira e produzir a equidade requerida pela democracia moderna.
Mounier e a condição da mulher
Authors: Andreola Balduino Antonio 
Published: July 2017

Em 1936, saiu um número de Esprit intitulado A mulher também é uma pessoa, com artigo no qual Mounier denuncia que houve revoluções contra a opressão dos proletários, mas nenhuma em defesa de um proletariado muito maior, o das mulheres. Contra a rejeição quase geral, 13 anos após, vê positivamente, embora com reservas, o livro de S. Beauvoir O Segundo Sexo. Retoma o tema “a condição da mulher” nos livros Manifesto a serviço do Personalismo, Tratado do caráter, Quando a cristandade morre, O Personalismo. As posições de Mounier em defesa da dignidade da mulher e suas denúncias dos preconceitos da época contra ela e das concepções da Igreja, justificando seu confinamento doméstico e sua total submissão ao homem, são amplamente resgatadas por estudiosos como Giulia P. Di Nicola, Michelle Perrot e Attilio Danese. Sua visão de mundo e de Igreja fazem-no precursor leigo do Vaticano II. A mulher que busca sua libertação como indivíduo, enfrentará, mesmo na liberdade conquistada, os limites e as amarras do individualismo, se não puder abrir-se, como pessoa, à alteridade e à transcendência, na plenitude de sua vocação humana.
Impulsividad y conducta alimentaria en varones
Authors: Olano Yalta Anthonny Micheel 
Published: July 2017

Leímos con interés el reciente artículo titulado “Impulsividad y conducta alimentaria en varones”, por lo cual quisiéramos hacer algunos comentarios. En primer lugar, los autores han usado la escala de impulsividad de Barratt diseñada para evaluar la impulsividad y la escala Eating Attitudes test - 40 (EAT-40) para medir las alteraciones alimentarias en una población estudiada que tiene rasgos psicológicos intrínsecos a su profesión que afectan su comportamiento, ya que ellos están expuestos a un estrés constante. (1) Así mismo, existe evidencia que los soldados al inicio de su etapa de formación tienen dificultades para adaptarse a la vida militar mostrando impulsividad. Ellos viven en un estado de tensión y percepción de riesgo constante, que ocasiona un estrés en ellos y por consiguiente alteraciones físicas y/o psicológicas. (1) Otro estudio menciona que un profesional de fuerzas armadas pasa un largo periodo de estrés como consecuencia de haber sido sometido a un sobreesfuerzo físico y mental en un largo período de tiempo. (2) Además, el entrenamiento militar ha demostrado que es un factor de estrés, ya que los soldados expuestos a esta actividad tienen niveles de cortisol elevados, siendo el estrés un potencial confusor y que debería ser considerado en su estudio con la finalidad de disminuir el riesgo de sesgo. (3)Finalmente, coincidimos con los autores que una limitación es el hecho de ser una muestra de aspirantes a militar profesional, la cual es una población muy selecta, lo cual hace difícil extrapolar los resultados a la población en general. Este estudio muestra la necesidad de más y mejores estudios sobre la conducta alimentaria en hombres, especialmente en grupos con potencial mayor riesgo como deportistas y/o jóvenes, ya que la literatura encontrada suele centrarse solo en mujeres. (4)
LA ACTIVIDAD FÍSICA EN EL CURRÍCULO UNIVERSITARIO ESPAÑOL DE LOS GRADOS DE MEDICINA Y CIENCIAS DE LA ACTIVIDAD FÍSICA Y DEL DEPORTE COMO RECURSO EN LA PREVENCIÓN Y TRATAMIENTO DE LAS ENFERMEDADES CRÓNICAS
Authors: CALONGE PASCUAL SERGIO , Casajús Mallén José Antonio , González Gross Marcela 
Published: July 2017

Introducción: La evidencia científica ha acreditado los beneficios que posee la actividad física sobre la salud. El objetivo de esta revisión fue analizar la formación curricular de los estudiantes de Medicina y de Ciencias de la Actividad Física y del Deporte (CAFD) en las universidades españolas, en relación a la prevención y el tratamiento de enfermedades crónicas a través de la actividad y el ejercicio físico.Material y métodos: De manera sistemática, se han revisado los planes de estudio de todas las Universidades españolas que tienen capacidad legal para impartir de forma presencial, los grados de Medicina y CAFD, contabilizando el promedio de créditos ECTS (European Credit Transfer System) totales, obligatorios y optativos de las asignaturas que abordan la promoción, prevención y tratamiento de las enfermedades crónicas a través del ejercicio físico. Se han excluido los practicum y los trabajos fin de grado.Resultados: El grado de Medicina dedica un promedio de 3,62% (2,38% y 1,20% créditos obligatorios y optativos, respectivamente) (360 ECTS) y el grado de CAFD un 17,78% (9,87% y 7,92%) (240 ECTS) a contenidos relacionados con la actividad física como herramienta en la prevención y tratamiento de las enfermedades crónicas no trasmisibles. El rango va de 36 a 4,5 ECTS en Medicina y de 48 a 28 ECTS en CAFD.Conclusión: Se observa cierta disparidad entre los planes de estudio de las universidades españolas para los dos Grados. Los créditos ECTS relacionados con actividad física y salud resultan escasos de asignaturas en el currículo de ambos grados, especialmente en Medicina. Los resultados indican la necesidad de aumentar estos contenidos en los estudios de grado y/o incluirlos en programas de postgrado.
DOCUMENTO DE CONSENSO DE EXPERTOS DE ANDALUCIA Y EXTREMADURA SOBRE LA NUTRICION PARENTERAL DOMICILIARIA.
Authors: Gonzalez Aguilera Beatriz , Olveira Gabriel , García Luna Pedro Pablo , Pereira Cunill Jose Luis , Luengo Perez Luis Miguel , Perez de la Cruz Antonio , Irles Rocamora Jose Antonio 
Published: July 2017

La Nutrición Parenteral en Domicilio es una técnica que ha permitido la supervivencia en la comunidad de aquellos pacientes con enfermedades graves resultantes en un fallo intestinal que hacía imposible su nutrición por otros métodos. Es un proceso complejo y a pesar de que existe una amplia experiencia en su aplicación e incluso Guías de Práctica Clínica, en la práctica diaria se plantean controversias acerca de su conveniencia, utilidad, uso racional y costes asociados. Por este motivo se ha realizado este documento de consenso, con el método GRADE con el que pretendemos definir nuestra posición con respecto al uso actual de la NPD en nuestro país, y que puede ayudar en la toma de decisiones.
Mean square calculus and random linear fractional differential equations: Theory and applications
Authors: Burgos C. , Cortés J.C , Villafuerte L. , Villanueva R.J. 
Published: July 2017

Abstract
The aim of this paper is to study, in mean square sense, a class of random fractional linear differential equation where the initial condition and the forcing term are assumed to be second-order random variables. The solution stochastic process of its associated Cauchy problem is constructed combining the application of a mean square chain rule for differentiating second-order stochastic processes and the random Fröbenius method. To conduct our study, first the classical Caputo derivative is extended to the random framework, in mean square sense. Furthermore, a sufficient condition to guarantee the existence of this operator is provided. Afterwards, the solution of a random fractional initial value problem is built under mild conditions. The main statistical functions of the solution stochastic process are also computed. Finally, several examples illustrate our theoretical findings.