bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of family relationships and outcomes of dementia: a systematic review
Authors: Edwards Hannah B , Ijaz Sharea , Whiting Penny F , Leach Verity , Richards Alison , Cullum Sarah J , Cheston Richard IL , Savović Jelena 
Published: January 2018

ObjectivesTo evaluate the association between the quality of relationship between a person with dementia and their family carer and outcomes for the person with dementia.DesignSystematic review.Eligibility criteriaCohort studies of people with clinically diagnosed dementia and their main carers. Exposures of interest were any elements of relationship quality, for example, attachment style, expressed emotion and coping style. Our primary outcome was institutionalisation, and secondary outcomes were hospitalisation, death, quality of life and behavioural and psychiatric symptoms of dementia (‘challenging behaviour’).Data sourcesMEDLINE, Embase, Web of Science, PsycInfo, the Cochrane Library and Opengrey were searched from inception to May 2017.Study appraisal and synthesis methodsThe Newcastle-Ottawa Scale was used to assess risk of bias. A narrative synthesis of results was performed due to differences between studies.ResultsTwenty studies were included. None of the studies controlled for all prespecified confounding factors (age, gender, socioeconomic status and severity of dementia). Reporting of results was inadequate with many studies simply reporting whether associations were ‘statistically significant’ without providing effect size estimates or CIs. There was a suggestion of an association between relationship factors and global challenging behaviour. All studies evaluating global challenging behaviour provided statistical evidence of an association (most P values below 0.02). There was no consistent evidence for an association for any other outcome assessed.ConclusionsThere is currently no strong or consistent evidence on the effects of relationship factors on institutionalisation, hospitalisation, death or quality of life for people with dementia. There was a suggestion of an association between relationship factors and challenging behaviour, although the evidence for this was weak. To improve our ability to support those with dementia and their families, further robust studies are needed.PROSPERO registration numberCRD42015020518.
Validity of self-reported age at menarche in computer-assisted interview among Chinese schoolgirls: a cross-sectional study
Authors: Mao Yanyan , Lian Qiguo , Zuo Xiayun , Zhang Yan , Luo Shan , Zhang Shucheng , Tu Xiaowen , Lou Chaohua , Zhou Weijin 
Published: January 2018

ObjectiveThe attitudes of girls regarding menarche vary according to their cultural backgrounds. Asian girls may hesitate to discuss menarche. Computer-assisted self-administered interviewing (CASI) is considered a valid and effective tool for investigating the timing of menarche; however, the validity of self-reported menarche data from CASI in Chinese culture is currently unknown. We aimed to validate the status and age of menarche attainment by comparing CASI with face-to-face interviewing (FFI).MethodsBased on a cross-sectional study, we collected information regarding the status and age of menarche attainment using CASI and FFI among Chinese schoolgirls. We explored the tools of standard epidemiological indices, including sensitivity, specificity, predictive values and accuracy to examine the capacity of CASI for correctly classifying the status of menarche. Both Pearson and Spearman correlations were calculated for the correlation of age at menarche using CASI with FFI. A Bland-Altman plot was drawn to measure the agreement between the two interview techniques.ResultsIn this study, CASI and FFI were conducted in 3478 schoolgirls with an average age (SD) of 14.3 years (2.46). Menarche attainment was reported in 2496 (71.2%) and 2538 (73.0%) girls using CASI and FFI, respectively. Compared with FFI, the sensitivity, specificity, positive predictive value (PPV), negative predictive value and the accuracy of CASI were 0.97, 0.80, 0.96 and 0.92, respectively. The correlation of age at menarche between CASI and FFI was 0.728. Approximately >95% and 76.3% of the difference in the age at menarche was within 12 months and 3 months, respectively, between the two interview methods. Among primary schoolgirls in grade 5, the sensitivity, specificity, PPV, accuracy and the correlation (0.335) of CASI was lower than those in other subgroups.ConclusionsOverall, the timing of menarche investigated using CASI was valid among all Chinese schoolgirls, except for those in grade 5 or lower.
The journey through care: study protocol for a longitudinal qualitative interview study to investigate the healthcare experiences and preferences of children and young people with life-limiting and life-threatening conditions and their families in the West Midlands, UK
Authors: Mitchell Sarah , Slowther Anne-Marie , Coad Jane , Dale Jeremy 
Published: January 2018

IntroductionThe number of children and young people living with life-limiting and life-threatening conditions is rising. Providing high-quality, responsive healthcare for them and for their families presents a significant challenge. Their conditions are often complex and highly unpredictable. Palliative care is advocated for people with life-limiting and life-threatening conditions, but these services for children are highly variable in terms of availability and scope. Little is known about the lived experiences and preferences of children and their families in terms of the palliative care that they do, or do not, receive. This study aims to produce an in-depth insight into the experiences and preferences of such children and families in order to develop recommendations for the future provision of services. The study will be carried out in the West Midlands, UK.Methods and analysisA qualitative study comprising longitudinal interviews over a 12-month period with children (aged 5–18 years) living with life-limiting or life-threatening conditions and their family members. Data analysis will start with thematic analysis, followed by narrative and cross-case analysis to examine changing experiences and preferences over time, at the family level and within the wider healthcare system. Patient and public involvement (PPI) has informed the design and conduct of the study. Findings will be used to develop recommendations for an integrated model of palliative care for children in partnership with the patient and public involvement (PPI) group.Ethics and disseminationEthical approval was granted in September 2016 by the National Health Service Health Research Authority (IRAS ID: 196816, REC reference: 16/WM/0272). Findings will be of immediate relevance to healthcare providers, policy-makers, commissioners and voluntary sector organisations in the UK and internationally. Reports will be prepared for these audiences, as well as for children and their families, alongside academic outputs.
Seremban Cohort Study (SECOST): a prospective study of determinants and pregnancy outcomes of maternal glycaemia in Malaysia
Authors: Yong Heng Yaw , Mohd Shariff Zalilah , Rejali Zulida , Mohd Yusof Barakatun Nisak , Yasmin Farah , Palaniveloo Lalitha 
Published: January 2018

IntroductionBoth gestational diabetes mellitus (GDM) and hyperglycaemia less severe than GDM are associated with risk of adverse pregnancy outcomes. We describe the study design of a prospective cohort of pregnant women recruited in early pregnancy with follow-ups of mothers and infants up to 2 years after birth. The primary aim of the study was to identify the determinants and outcomes of maternal glycaemia.Methods and analysisSeremban Cohort Study (SECOST) is an ongoing prospective cohort study in which eligible pregnant women in first trimester (<10 weeks of gestation) are recruited from Maternal and Child Health clinics in Seremban District, Negeri Sembilan with seven follow-ups during pregnancy through 2 years postnatally. Infants are followed up every 6 months after birth until 2 years old. A standard 75 g oral glucose tolerance test is performed between 24 and 32 of weeks of gestation and as close to 28 weeks of gestation. Pregnancy and birth information are obtained from medical records. Sociodemographic, anthropometric, biochemical, dietary, physical activity, smoking, depression, child feeding and other data of mothers and infants are obtained at follow-ups.Ethics and disseminationThis study is approved by the Medical Research Ethics Committee (MREC), Universiti Putra Malaysia (UPM/FPSK/100-9/2-MJKEtika) and MREC, Ministry of Health Malaysia (KKM/NIHSEC/08/0804/P12- 613). Permission to conduct this study is also obtained from the Head of Seremban District Health Office. All participants are required to provide written informed consent prior to data collection. The research findings will be disseminated at journals and conference presentations.
Engaging older people in an internet platform for cardiovascular risk self-management: a qualitative study among Dutch HATICE participants
Authors: van Middelaar Tessa , Beishuizen Cathrien R L , Guillemont Juliette , Barbera Mariagnese , Richard Edo , Moll van Charante Eric P 
Published: January 2018

ObjectivesTo study older peoples’ experiences with an interactive internet platform for cardiovascular self-management, to assess which factors influence initial and sustained engagement. To assess their views on future use within primary care.DesignQualitative semistructured interview study, with thematic analysis.SettingPrimary care in the Netherlands.ParticipantsPeople ≥65 years with an increased risk of cardiovascular disease who used the ‘Healthy Ageing Through Internet Counselling in the Elderly’ internet platform with remote support of a coach. Participants were selected using a purposive sampling method based on gender, age, level of education, cardiovascular history, diabetes, duration of participation and login frequency.ResultsWe performed 17 interviews with 20 participants, including three couples. In the initial phase, platform engagement was influenced by perceived computer literacy of the participants, user-friendliness, acceptability and appropriateness of the intervention and the initial interaction with the coach. Sustained platform use was mainly facilitated by a relationship of trust with the coach. Other facilitating factors were regular automatic and personal reminders, clear expectations of the platform, incorporation into daily routine, social support and a loyal and persistent attitude. Perceived lack of change in content of the platform could work both stimulating and discouraging. Participants supported the idea of embedding the platform into the primary care setting.ConclusionsHuman support is crucial to initial and sustained engagement of older people in using an interactive internet platform for cardiovascular self-management. Regular reminders further facilitate sustained use, and increased tailoring to personal preference is recommended. Embedding the platform in primary healthcare may enhance future adoption.Trial registration numberISRCTN48151589; Pre-results.
Patient experience of general practice and use of emergency hospital services in England: regression analysis of national cross-sectional time series data
Authors: Cowling Thomas E , Majeed Azeem , Harris Matthew J 
Published: January 2018

BackgroundThe UK Government has introduced several national policies to improve access to primary care. We examined associations between patient experience of general practice and rates of visits to accident and emergency (A&E) departments and emergency hospital admissions in England.MethodsThe study included 8124 general practices between 2011–2012 and 2013–2014. Outcome measures were annual rates of A&E visits and emergency admissions by general practice population, according to administrative hospital records. Explanatory variables included three patient experience measures from the General Practice Patient Survey: practice-level means of experience of making an appointment, satisfaction with opening hours and overall experience (on 0–100 scales). The main analysis used random-effects Poisson regression for cross-sectional time series. Five sensitivity analyses examined changes in model specification.ResultsMean practice-level rates of A&E visits and emergency admissions increased from 2011–2012 to 2013–2014 (310.3–324.4 and 98.8–102.9 per 1000 patients). Each patient experience measure decreased; for example, mean satisfaction with opening hours was 79.4 in 2011–2012 and 76.6 in 2013–2014. In the adjusted regression analysis, an SD increase in experience of making appointments (equal to 9 points) predicted decreases of 1.8% (95% CI −2.4% to −1.2%) in A&E visit rates and 1.4% (95% CI −1.9% to −0.9%) in admission rates. This equalled 301 174 fewer A&E visits and 74 610 fewer admissions nationally per year. Satisfaction with opening hours and overall experience were not consistently associated with either outcome measure across the main and sensitivity analyses.ConclusionsAssociations between patient experience of general practice and use of emergency hospital services were small or inconsistent. In England, realistic short-term improvements in patient experience of general practice may only have modest effects on A&E visits and emergency admissions.
‘Stabilising the Balkans’
Authors: Mulaj Jeta 
Published: January 2018

Abstract
This review essay discusses Welcome to the Desert of Post-Socialism: Radical Politics After Yugoslavia. This volume, edited by Srećko Horvat and Igor Štiks, critiques a reductive neoliberal narrative regarding the Balkans in relation to Western Europe by examining the disastrous consequences of the transition of post-socialist countries to capitalism. The volume provides a critical engagement with socialist Yugoslavia and an affirmation of the possibilities of radical anti-capitalist struggles. This review examines the critique of transition politics by focusing on concepts of stability, racism and questions of temporality.
Making Revolutionary Fire
Authors: Ritchie Genevieve B. 
Published: January 2018

AbstractThe edited collectionMarxism and Feminismtraces both the conceptual divides and political affinities between feminism and Marxism. Utilising a keywords-, or core-concepts approach, the book fleshes out the tensions and contradictions that organise and orient Marxist and feminist theories and practices of social transformation. The concepts discussed inMarxism and Feminismdo not try to bridge divergent theories of exploitation or oppression; rather the tensions between feminism and Marxism are used to generate new terrains of investigation. Although the topics discussed vary widely, the book is held together by a commitment to dialectical-materialist investigation and revolutionary social transformation.
Multidecadal Variability in Global Surface Temperatures Related to the Atlantic Meridional Overturning Circulation
Authors: Stolpe Martin B. , Medhaug Iselin , Sedláček Jan , Knutti Reto 
Published: January 2018

Multidecadal internal climate variability centered in the North Atlantic is evident in sea surface temperatures and is assumed to be related to variations in the strength of the Atlantic meridional overturning circulation (AMOC). In this study, the extent to which variations in the AMOC may also alter hemispheric and global surface air temperature trends and ocean heat content during the past century is examined. Forty-seven realizations of the twentieth-century climate change from two large ensembles using the Community Earth System Model (CESM) are analyzed. One of the ensembles shows a much wider spread in global mean surface air temperature between its members. This ensemble simulates diverging trends of the AMOC strength during the twentieth century. The presence and strength of deep convection in the Labrador Sea controls these trends. The AMOC strength influences the air–sea heat flux into the high-latitude ocean, where a strengthening of the AMOC leads to decreased storage of heat in the Atlantic, and a larger fraction of the heat taken up by the global ocean accumulates in the top 300 m, compared to the case of a weakening AMOC. The spread in the amount of heat stored in the global ocean below 300 m is similar across the CESM members as in a set of CMIP5 models, confirming the AMOC as a “control knob” on deep-ocean heat storage. By influencing the ocean heat uptake efficiency and by shifting the pattern of heat uptake, global surface air temperatures are significantly altered on a multidecadal time scale by AMOC variability.
Vitamin A–coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease
Authors: Yamakawa Tomohiro , Ohigashi Hiroyuki , Hashimoto Daigo , Hayase Eiko , Takahashi Shuichiro , Miyazaki Miyono , Minomi Kenjiro , Onozawa Masahiro , Niitsu Yoshiro , Teshima Takanori 
Published: January 2018

Key Points
HSP47+ myofibroblasts are accumulated in the fibrotic lesions of chronic GVHD and promote fibrosis in a CSF-1R+ macrophage-dependent manner. Vitamin A–coupled liposomes containing HSP47 siRNA abrogate HSP47 expression in myofibroblasts and ameliorate fibrosis in chronic GVHD.
Constraining electric resistivity tomography by direct push electric conductivity logs and vibracores: An exemplary study of the Fiume Morto silted riverbed (Ostia Antica, western Italy)
Authors: Wunderlich Tina , Fischer Peter , Wilken Dennis , Hadler Hanna , Erkul Ercan , Mecking Rebekka , Günther Thomas , Heinzelmann Michael , Vött Andreas , Rabbel Wolfgang 
Published: January 2018

The inversion of geoelectric data is nonunique. Therefore, electric resistivity tomography (ERT) usually results in different subsurface models that fit observed apparent resistivity values equally well. To reduce the uncertainty, constraints on the geometry and resistivity of subsurface structures can be incorporated into the ERT inversion. We test different ways of constraining ERT by applying (1) improved starting models, (2) structural constraints, and (3) structural and resistivity constraints. A priori information is needed for these approaches, which is acquired from direct push electrical conductivity (DP-EC) logs and vibracores in our study. We found that adapting high vertical resolution of DP-EC logs to coarser ERT resolution requires blocking of the logs. These blocked logs can be used for constraining the ERT inversion with resistivity and structural constraints along so-called regions around the log locations, which was found to be the best approach. In this case, ground truthing with additional DP-EC logs that were not used for constraining showed the lowest root-mean-square error between logs and ERT model.
Limits to sustained energy intake XXVII: trade-offs between first and second litters in lactating mice support the ecological context hypothesis
Authors: Vaanholt Lobke Maria , Duah Osei Agyeman , Balduci Suzanna , Mitchell Sharon Elizabeth , Hambly Catherine , Speakman John Roger 
Published: January 2018

Increased reproductive effort may lead to trade-offs with future performance and impact offspring, thereby influencing optimal current effort level. We experimentally enlarged or reduced litter size in mice during their first lactation, and then followed them through a successive unmanipulated lactation. Measurements of food intake, body mass, milk energy output (MEO), litter size and litter mass were made. Offspring from the first lactation were also bred to investigate their reproductive success.
In their first lactation, mothers with enlarged litters (n=9, 16 pups) weaned significantly smaller pups, culled more pups, and increased MEO and food intake compared to mothers with reduced litters (n=9, 5 pups). In the second lactation no significant differences in pup mass or litter size were observed between groups, but mothers that previously reared enlarged litters significantly decreased pup mass, MEO and food intake compared to mothers with reduced litters. Female offspring from enlarged litters displayed no significant differences in any of the other variables measured compared to female offspring from reduced litters, but did wean slightly smaller pups.
These results suggest that females with enlarged litters suffered from a greater energetic burden during their first lactation, and this was associated with lowered performance in a successive reproductive event and impacted on their offspring's reproductive performance. Female ‘choice’ about how much to invest in the first lactation may thus be driven by trade-offs with future reproductive success, and hence the ‘limit’ on performance may not be a hard physiological limit. These data support the ecological-context-hypothesis.
Accounting and Analytical Provision of Updates Basic Funds: Selecting Sources of Financing
Authors: Золотарева Г. , Zolotareva G. , Бахмарева Н. , Bahmareva N. 
Published: January 2018

Th e article offers recommendations for the control of alternative sources of financing of renovation of fixed assets, taking into account risk factors, including risks directly related to the change in the level of financial sustainability of the organization. The use of these recommendations, management of organization will have the opportunity to organize the
assessment of the potential of existing portfolio total cash flows expected from each involved source of investment by their members in the aisles of the planning horizon.
The weight of Light Contradictions for Susan Rose and dancers: An exercise in parallel processing and power
Authors: Schwadron Hannah 
Published: January 2018

Abstract
This article returns to the improvisatory practice of Los Angeles-based choreographer, Susan Rose and her 1978 dance work, Light Contradictions. Analysis of the rule-based improvisation illuminates a critical choreographic practice based on parallel processing and power plays that has sustained in performance for four decades. Reliant on its simple rules, Light Contradictions makes its main message known: Do what I say as I say it, and I’ll do whatever you tell me to. The doing and saying duet appears friendly enough as an arrangement based on equal parts. What ensues, however, is the hysteria of two people – or several sets of two – as they aim to draw out a boundless repertoire of tasks and actions by way of bossing each other around. As the piece travels, rotating performers and crowds, it acts as a platform for keen interpersonal provocation and cultural exchange, simultaneity and contradiction.
Storytelling threads
Authors: Araujo Rosangela de 
Published: January 2018

Abstract
A silent ‘I am’ on the foot of an abandoned doll. An uttered ‘I am a cactus’. Line Klungseth Johansen weaves enigmatic messages into an apparently straightforward account of a brief love affair. What is she actually telling us? A search for hints in Flimmer’s poetic and subtle fabric. An interpretation.
Price Analysis of Different Options for Thermal Insulation of Vasil Levski National Military University Headquarters
Authors: Filipov Stefan 
Published: January 2018

Abstract
The paper presents the maintenance of the buildings property of MOD and BA. In perspective, the maintenance of a building can increase the efficiency level significantly, as well as part of it being given under rent to generate income for the budget of MOD. Comparative price analysis of different options and suboptions for thermal insulation of Vasil Levski National Military University Headquarters has been made and the most cost-effective option has been determined.