bluuebunny/crossref_metadata_2025_split huggingface dataset:
The brand behind the curtain: decoupling, recoupling and moral conflict in social media
Authors: Gambetti Rossella C. , Kozinets Robert , Biraghi Silvia 
Published: October 2024

Purpose
Social media platforms have matured into significant arenas for moral conflict and often intense confrontation between brands and their consumers. This research aims to scrutinize the strategic development of a fresh brand entity deliberately detached from its morally compromised corporate parent, intended to reshape public perceptions and elude regulatory scrutiny.

Design/methodology/approach
Promoted as a center for transformative dialogue and innovation, Mission Winnow by Philip Morris is a novel example of a brand creating an entirely separate brand entity to provide sponsorship, and to associate itself with new brand values. This study employs a multisited netnography through which the posts and conversations on Mission Winnow’s platform and website hub are captured and interpreted, as well as the branded content and the free flows of consumers’ conversations generated around the brand on social media.

Findings
Findings reveal a broad interchange of moral controversy, acceptance and opposition discourses on social media. When consumers’ acceptance narratives gain traction, consumers extend their support toward the new brand entity, employing strategies that echo moral rationalization and decoupling. When resistance narratives dominate, consumers consciously draw connections between the decoupled brand and the parent brand’s immoral behavior.

Originality/value
This study expands upon prior research into brand activism and consumers’ moral reasoning toward controversial brands, linking the notion of brand decoupling to brand activism discourse and introducing key underexplored aspects like the power of imagery, linguistic creativity and nostalgia. Moreover, it presents significant implications for a more nuanced understanding of the important interrelationship of brand decoupling and recoupling on social media.
Ruby Princess case study: a systems thinking analysis of COVID-19, cruise ships and Australia’s response
Authors: Cartwright Dimitra (Jenny) , McNulty Joseph 
Published: October 2024

PurposeThe COVID-19 pandemic tested leadership in chaos and complexity and resulted in many lessons learnt in the process. One such opportunity was the cruise ship Ruby Princess “mishap” in Australia which resulted in the failure to quarantine the virus onboard the cruise ship thus allowing transmission into the Australian community. The purpose of this paper is to use the Ruby Princess as a case study and apply a systems thinking analysis to it.Design/methodology/approachWhilst many inquiries and commissions have documented the failings of the agencies or “systems” involved in the Ruby Princess, the Ruby Princess case study provides a suitable example for the application of systems thinking analysis. The paper proceeds by identifying the various agencies either directly or indirectly involved in the Ruby Princess disaster and groups them based on the system they represented (state; federal; international or cruise-based system). These systems were mapped providing a visual representation of the complexity of the landscape in which police and public safety agencies had to operate in to respond to the Ruby Princess.FindingsOver 30 agencies were found to be either directly or indirectly involved in the Ruby Princess. Following the application of systems thinking analysis, it was clear that the various systems were operating in silos, thus failing to fully exploit the interconnections between and within all the systems which ultimately resulted in the Ruby Princess.Practical implicationsThe results of this analysis have informed a series of recommendations for leadership development within similar contexts, including embracing a systems thinking approach.Originality/valueUsing the Ruby Princess as a case study, this article presents a novel approach through the application of systems thinking and how it can enhance a leader’s ability to navigate the current “new normal” operating environment. It highlights the importance of public safety leadership moving away from an insular systems focus towards more of a public sector partnership which is an imperative for police and other public safety agencies to navigate through times of complexity and chaos.
Dr. Meena and mission maternal health: building allies in the government hospital
Authors: Vyas Diti Pundrik , Bhakare Shilpa Hemant , Iyer Veena , Panchamia Jallavi 
Published: October 2024

Research methodology
The case study is based on field data, including in-depth semi-structured interviews with the main protagonist and related stakeholders of a large government hospital in Western India. After informed consent, the interviews with the stakeholders were conducted, transcribed and analyzed verbatim. In addition, secondary data from policy reports, newspaper articles and government websites was used to create the case. Since the protagonist works in the government system, her identity and other identifying information are disguised to maintain confidentiality.

Case overview/synopsis
The case study investigates the leadership challenges in a healthcare facility/hospital in public health. It traces the evolution of Dr Meena Sharma (Dr Meena), a leader in the government hospital ecosystem facing challenges such as infrastructural deficiencies, manpower deficit, healthcare bureaucracy and heavy patient load. This first-generation medical practitioner who transitioned from a private practice to a governmental one juggles balancing her demanding clinical practice, administrative responsibilities and teaching in the government hospital with her family responsibilities setup. However, in the wake of the upcoming LaQshya – Labour Room Quality Improvement Initiative by the Ministry of Health & Family Welfare, she strives to put together and motivate her team to work toward improving the quality of care during delivery and the immediate postpartum period at her hospital. Various issues arise in the organizational leadership for a woman leader such as adopting appropriate leadership style and using appropriate motivation and communication strategies for optimal performance.

Complexity academic level
The case study is aimed at teaching/training a) departmental heads of public and private hospitals, b) health program managers at higher and middle-level leadership roles, c) health policymakers at various levels in the government and other organizations and d) graduate and postgraduate students of public health, hospital management/administration. In addition to this, it can also be used for general management programs to teach organizational behavior, communication and leadership courses.
Simulation-based design: minimizing energy consumption in residential buildings through optimal thermal insulation
Authors: Amani Nima 
Published: October 2024

Purpose
This study aims to optimize the energy consumption of residential buildings in mild and humid climates. It investigates the use of thermal insulation to reduce thermal load through energy simulation analysis.

Design/methodology/approach
A residential building located in Rasht city, Iran (a mild and humid climate zone), is simulated using DesignBuilder software. Subsequently, the minimum thermal resistance for external walls and roof is analyzed along with its impact on building energy consumption and carbon emissions.

Findings
The simulation results indicated a 26.5% reduction in heat loss through the walls and a 14.2% reduction through the roof due to optimal thermal insulation. Furthermore, optimal insulation led to a 19.2% reduction in cooling system energy use, a 12% reduction in heating system energy use and a combined 15.3% reduction in total energy consumption for cooling and heating.

Originality/value
This optimization process leads to several benefits: reduced costs associated with thermal and cooling energy losses in buildings, improved building performance against atmospheric factors and, ultimately, a reduction in energy consumption across the building industry. This research can be valuable to various stakeholders, including the construction industry and building sector, municipalities and engineering systems, building owners and contractors and environmental organizations. By implementing these findings, they can improve the state of modern building insulation and achieve greater energy efficiency.
Oral, Vaginal, and Stool Microbial Signatures in Patients With Endometriosis as Potential Diagnostic Non‐Invasive Biomarkers: A Prospective Cohort Study
Authors: Hicks Chloe , Leonardi Mathew , Chua Xin‐Yi , Mari‐Breedt Lisa , Espada Mercedes , El‐Omar Emad M. , Condous George , El‐Assaad Fatima 
Published: October 2024

ABSTRACTObjectiveTo identify a microbial signature for endometriosis for use as a diagnostic non‐invasive biomarker.DesignProspective cohort pilot study.SettingNepean Hospital and UNSW Microbiome Research Centre, Australia.PopulationSixty‐four age‐ and sex‐matched subjects (n = 19 healthy control (HC); n = 24 non‐endometriosis (N‐ENDO) and n = 21 confirmed endometriosis (ENDO)). All study participants, besides healthy controls, underwent laparoscopic surgical assessment for endometriosis, and histology was performed on excised lesions.MethodsOral, stool and, vaginal samples were self‐collected at a single time point for healthy controls, and preoperatively for patients undergoing laparoscopy. Samples underwent 16S rRNA amplicon sequencing, followed by bioinformatics analysis.Main Outcome MeasuresCompositional differences between cohorts as identified by diversity analyses, and differentially abundant microbial taxa, as identified by LEfSE analysis.ResultsThe composition of the oral (adjusted p = 0.003), and stool (adjusted p = 0.042) microbiota is different between the three cohorts. Differentially abundant taxa are present within each cohort as identified by LEfSE analysis. Particularly, Fusobacterium was enriched in the oral samples of patients with moderate/severe endometriosis.ConclusionsTaxonomic and compositional differences were found between the microbiota in the mouth, gut and, vagina of patients with and without endometriosis and healthy controls. Fusobacterium was enriched in patients with moderate/severe endometriosis. Fusobacterium is noted as a key pathogen in periodontal disease, a common comorbidity in endometriosis. These findings suggest a role for the oral, stool and, vaginal microbiome in endometriosis, and present potential for microbial‐based treatments and the design of a diagnostic swab.
Discrepancy model to RtI: Gauging teacher preparedness for this shift in specific learning disability classification
Authors: Hogan Joseph A. 
Published: October 2024

AbstractThe Individuals with Disabilities Education Improvement Act (2004) allows alternate pathways for school districts to identify and classify students with a specific learning disability (SLD). Response to Intervention (RtI) is one of the frameworks schools can use when eliminating the use of the discrepancy model. The premise of RtI posits that tiered instruction can assist all students who are struggling through utilizing research‐based interventions. When these tiers of intervention services are exhausted with limited to no response to the intervention, a child can be classified under the SLD category. There are documented concerns with effective implementation of RtI frameworks. This qualitative exploratory study examined the perceptions of teachers in a graduate education program regarding the knowledge, usage and implementation of RtI to classify students with a SLD. Through thematic analysis, findings indicate a need for more training in districts, better preparation at the university level and more support in applying RtI in the classroom. Implications for practice and future research are discussed.
Amputation and limb‐sparing surgery in childhood sarcoma: Post‐operative imaging appearances and complications
Authors: Earley Joel , Roebuck Derek 
Published: October 2024

AbstractLimb‐sparing surgery and amputation are common surgical techniques used to achieve local tumour control in childhood primary bone and soft tissue malignancy of the limbs. The interpretation of post‐operative limb imaging in these frequently complex cases is assisted by knowledge of the surgical techniques employed. This review discusses the rationale underpinning the most common surgical techniques used for these patients as well as their expected post‐operative imaging appearance and complications. Amputation, long bone resection, endoprosthetic reconstruction, allograft reconstruction, the use of fibular autografts, allograft‐prosthetic composite reconstruction and arthrodesis are discussed.
Ambiguity or specificity: The influence of merchant guild culture on managers' disclosure strategy
Authors: Zhang Tingting , Yin Haozhou , Zhuang Zixuan 
Published: October 2024

AbstractRecent studies indicate that culture attributes significantly influence corporate behaviour. Building on this, our study explores how merchant guild culture (MGC) influences firms' voluntary disclosure practices, specifically through managerial disclosure strategies. Analysing data from Chinese listed firms between 2010 and 2022, we found that MGC significantly reduces the specificity of managerial responses at earnings communication conferences (ECCs). This suggests that firms influenced by MGC favour ambiguous communication, aligning with the value to mitigate competitive risks. Our findings deepen the understanding of cultural influences on corporate disclosure practices and extend literature on the role of informal institutions in corporate behaviours.
Immunoregulation and male reproductive function: Impacts and mechanistic insights into inflammation
Authors: Ma Yingjie , Yu Xinru , Liu Yi Fan , Song Bihan , Sun Zhengao , Zhao Shengtian 
Published: October 2024

AbstractThis paper investigates the complex relationship between the immune system and male reproductive processes, emphasizing how chronic inflammation can adversely affect male reproductive health. The immune system plays a dual role; it protects and regulates reproductive organs and spermatogenesis while maintaining reproductive health through immune privilege in the testes and the activities of various immune cells and cytokines. However, when chronic inflammation persists or intensifies, it can disrupt this balance, leading to immune attacks on reproductive tissues and resulting in infertility.This study provides a detailed analysis of how chronic inflammation can impair sperm production, sperm quality, and the secretion of gonadal hormones both directly and indirectly. It also delves into the critical roles of testicular immune privilege, various immune cells, and cytokines in sustaining reproductive health and examines the impacts of infections, autoimmune diseases, and environmental factors on male fertility.
Multidisciplinary protocol to reduce surgical readmissions in Australia: American College of Surgeons National Surgical Quality Improvement Program
Authors: Pham Helen , Hitos Kerry , Pawaskar Rishan , Sinclair Jane‐Louise , Mathuthu Hazel , Nahm Christopher B , Pang Tony , Lam Vincent , Richardson Arthur 
Published: October 2024

AbstractIntroductionUnplanned readmissions in general surgery are an important quality indicator of patient care and are associated with increased costs to healthcare services. This study aims to implement a multidisciplinary protocol in a single institution in a tertiary referral hospital to monitor and reduce unplanned readmission rates.MethodsA prospective cohort study using an institution‐based protocol was conducted over an 18‐month period including patients undergoing a general surgical procedure. The protocol included: (i) implementation of a surgical readmissions nurse–patient liaison; (ii) access to a surgical walk‐in clinic; and (iii) early post‐discharge phone contact. Data included demographic details, index procedure, hospital length of stay (LOS), and whether contact between patient/nurse occurred upon discharge. The primary outcome was the cause and rate of 30‐day readmissions. Secondary outcomes were mortality, use of surgical clinic, emergency department presentations, and complications.ResultsAfter protocol implementation, 874 patients underwent a general surgical procedure, with 354 (49%) being male and an overall median age of 53.0 years (interquartile range: 36.0–67.0). The overall readmission rate was 5.6% (n = 49), with a median LOS after readmission of 4 days. Compared with historical pre‐protocol ACS‐NSQIP data, this reflects a 30% reduction compared to that of readmission rate of 7.9%, P = 0.03.ConclusionThe multidisciplinary protocol was efficacious in significantly reducing unplanned readmissions. Continued audits and monitoring of factors associated with readmissions are required to help design targeted projects that may lead to improved outcomes, lower costs, increased patient satisfaction, and better efficiency within our healthcare system.
Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy
Authors: Forte Paolo , Cattaneo Jennifer , Cardillo Piccolino Felice , Arrigo Alessandro , Corazza Paolo , Musetti Donatella , Rosa Raffaella , Traverso Carlo Enrico , Fontana Vincenzo , Lupidi Marco , Eandi Chiara Maria , Nicolò Massimo 
Published: October 2024

AbstractPurposeTo test the prognostic role of anterior scleral substantia propria (ASSP) thickness in predicting the 3‐month response after half‐dose photodynamic therapy (PDT) in central serous chorioretinopathy (CSCR) and to assess its clinical relevance of ASSP in different CSCR phenotypes.MethodsA prospective, exploratory, multi‐centre cohort study conducted at IRCCS San Martino Hospital (Genoa, Italy) and Jules‐Gonin Eye Hospital (Lausanne, Switzerland). Demographic and clinical data, and optical coherence tomography (OCT) were collected at baseline and 3 months after PDT. Based on OCT images, we categorized CSCR phenotypes and collected clinically relevant imaging metrics. ASSP thickness was obtained from four different measurements using anterior segment (AS) OCT. Multivariable regression models were performed to evaluate the distribution of ASSP thicknesses among different CSCR phenotypes and to test the prognostic role of ASSP thickness in discriminating between PDT responders (complete subretinal fluid reabsorption) and partial responders.ResultsThe study cohort comprised 109 Caucasian patients (82 males, 75.2%) with a total of 142 eyes: 84 eyes simple (59.1%) versus 58 eyes complex (40.9%) CSCR. A linear normal model confirmed a positive association between complex CSCR and higher ASSP thickness (β = 26.1, 95% CL = 12.1/40.1, p < 0.001), with a low prevalence of ciliochoroidal effusion loculations in AS‐OCT (1/142 eyes, 0.7%). ASSP thickening was positively linked to the presence of posterior cystoid retinal degeneration (PCRD; p = 0.002), indicating a potential role in the pathogenesis of severe CSCR phenotypes. In the subgroup of treated patients (61 eyes), 63.9% had a complete response after PDT. In these patients a logistic binary model highlighted a significantly higher risk of PDT non‐responsiveness (OR = 9.62, 95% CL = 2.44/37.9, p = 0.001) associated with a 60‐unit increase in ASSP thickness levels. By contrast, other anatomical parameters (i.e., body surface area, age, gender, axial length) showed no remarkable prognostic roles.ConclusionThis research highlighted the association of ASSP thickening with complex CSCR phenotype in Caucasian patients and its role in predicting PDT efficacy. These findings enhance our comprehension of the anatomical risk factors in patients affected with CSCR and potentially guide a better understanding of non‐responsive cases to PDT treatment.
Single‐dose and steady‐state pharmacokinetics of clomipramine, yohimbine and clomipramine/yohimbine combination: A clinical drug–drug interaction study
Authors: Leutzendorff Amelie , al Jalali Valentin , Bauer Martin , Minichmayr Iris K. , Reiter Birgit , Duchek Michael Wölfl ‐ , Nussbaumer‐Pröll Alina , Weber Maria , Eberl Sabine , Spies Marie , Sarhan Maysa , Geilen Johannes , Walther Alexander , Drai Daniel , Zeitlinger Markus 
Published: October 2024

AbstractAimsClomipramine (CLOMI) has shown effectiveness in treating premature ejaculation but is linked to erectile dysfunction and reduced libido. Yohimbine (YOH), by contrast, is effective in treating erectile dysfunction and may improve libido. Combining CLOMI and YOH could potentially leverage the benefits of both drugs. This study aimed to investigate the interactions between these drugs and to evaluate their safety profile.MethodsA prospective, open‐labelled, single‐centre, pharmacokinetic (PK) drug–drug interaction study was performed in 15 healthy male subjects. Single‐dose and steady‐state PK were investigated using noncompartmental analysis after mono‐ and combination therapy of the 2 orally applied drugs. Plasma sampling was performed at baseline, 0.5 (YOH), 1, 1.5 (YOH), 2, 3, 4, 5, 6, 8, 12 and 24 h (CLOMI). Differences in the area under the curve after multiple dosing (MD) were determined using an equivalence boundary of 80–125%.ResultsThe geometric mean ratio of the area under the curve up to 12 h for MD CLOMI (combination vs. monotherapy) was 112% (90% confidence interval: 104–120%), whereas for MD YOH this ratio was 137% (90% confidence interval: 112–168%). The study drugs were safe and well tolerated as mono‐ and combination therapy, with no major adverse events reported.ConclusionA PK assessment of clomipramine and yohimbine indicated a clinically significant drug–drug interaction for MD YOH in combination with CLOMI. This might be explained by competitive, CLOMI‐related inhibition of YOH metabolism, probably mediated by cytochrome P450 2D6. However, according to European Medicines Agency guidelines, the effect can be classified as interaction absent (<1,25 fold) or minor (>1.25–<2‐fold). Given the complimentary mechanisms of action and the favourable safety profiles, the findings pave the way for future efficacy studies.
Challenging Institutional Path Dependence Through Field Configuring Events: Exploring the Collective Institutional Entrepreneurship of the Sustainable Stock Exchanges Initiative
Authors: Loren Steve 
Published: October 2024

ABSTRACTResearch Question/IssueHow can a global social movement, mobilized through a multi‐stakeholder initiative, promote the uptake of novel governance practices in distinct national institutional environments?Research Findings/InsightsUsing data from all 114 of the world's stock exchanges, covering over 99% of global stock market capitalization as of 2018, I find that exchanges in common‐law countries were more likely to become early partners of the Sustainable Stock Exchanges Initiative (SSEI) after its launch in 2012. However, exchanges based in civil‐law countries experienced a higher likelihood (i.e., risk) of adoption, as measured by the hazard ratio, particularly during a series of sustained field‐configuring events (FCEs) promoted by the SSEI. Over time, this increased hazard ratio indicated a rising likelihood of adoption for civil‐law‐based exchanges, eventually surpassing that of their common‐law counterparts.Theoretical/Academic ImplicationsWhile institutional environments' path dependency can facilitate or hinder the adoption of governance practices, collective institutional entrepreneurship (CIE) can moderate this path dependency and reveal new information regarding the structural fit between promoted governance practices and their institutional environments.Practitioner/Policy ImplicationsThe insights provided by this study can help practitioners understand why some practices face resistance in specific institutional environments, while others are more readily accepted. These insights also help practitioners communicate the elements of governance practices that implicitly align with the institutional environments in which they are seeking adoption.