bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eradication Rates in Italian Subjects Heterogeneously Managed for Helicobacter pylori Infection. Time to Abandon Empiric Treatments in Southern Europe
Authors: Di Ciaula Agostino , Scaccianoce Giuseppe , Venerito Marino , Zullo Angelo , Bonfrate Leonilde , Rokkas Theodore , Portincasa Piero 
Published: May 2017

Background & Aims: H. pylori eradication is strongly affected by various factors, including the ongoing antibiotic resistance. We describe a “real life” scenario in patients managed for H. pylori-related conditions, living in a southern Italian region (Apulia), an area with clarithromycin resistance >15%.Methods: 2,224 subjects were studied in two tertiary referral centers in Apulia. Analyses included: reason for referral, H. pylori infection rates (13C-urea breath test – UBT or upper endoscopy), and eradication rates following distinct regimens previously prescribed or prospectively prescribed (such as the bismuth-based quadruple therapy Pylera®, recently marketed in Italy).Results. Over 80% of the patients were referred by family physicians (60% naïve subjects). The overall infection rate was 32.5% and it was similar in asymptomatic patients (31.1%) or with H. pylori-related symptoms/clinical conditions (34.3%). In the 987 H. pylori+ve patients receiving therapy, the overall eradication rate was 80.2% (ITT). Observed eradication rate varied greatly across different regimens: 57.1% (2nd line levofloxacin), 59.6% (unconventional), 70.7% (7-day triple), 73.2% (7-day undefined), 89% (10-day sequential) and 96.9% (ITT, 10 day Pylera®, 1st to 5th line regimens given to 227 patients).Conclusions. A heterogeneous “real life” scenario in Southern Europe shows that H. pylori+ve patients are put at risk of poor outcomes and points to the need of a susceptibility-based therapy according to guidelines and local microbial resistance. In the present setting (i.e. high clarithromycin resistance), despite the high observed eradication rate, sequential therapy should not be recommended (absent in guidelines, unneeded antibiotic). Bismuth-based quadruple treatment (1st, 2nd or subsequent lines) yields the highest eradication rates.Abbreviations: ALT: Altamura; BA: Bari; EGDS: esophagogastroduodenoscopy; GERD: gastro-esophageal reflux disease; H. pylori: Helicobacter pylori; ITT: intention-to-treat; PP: per-protocol; PPI: proton pump inhibitor; UBT: urea breath test.
Peroral Endoscopic Myotomy for the Treatment of Achalasia in a Patient with Esophageal Varices. A Case Report
Authors: Shen Naning , Wang Xin , Zhang Xiaoyin , Yao Liping , Xie Huahong , Zhang Hongbo 
Published: May 2017

Achalasia is very uncommon, and rarely does achalasia co-exist with esophageal varices. We present a 62-year-old woman who was diagnosed with both achalasia and esophageal varices in December 2014 and had a past history of hematemesis. The patient’s achalasia symptoms’ Eckardt score was 9, and her hepatic function was Child-Pugh grade A6. After comprehensive assessment of the patient’s health and discussion of the pros and cons of various therapies for achalasia, the patient underwent a peroral endoscopic myotomy. She was symptom-free after the operation and had no recurrence of achalasia symptoms at 20-month follow-up. No adverse events were reported. Peroral endoscopic myotomy for achalasia with esophageal varices has not been previously reported in the English literature.Abbreviations: BTI: Botulinum toxin injections; EUS: Endoscopic ultrasonography; GEJ: Gastroesophageal junction; HIFU: High-intensity focused ultrasound; LHM: Laparoscopic Heller myotomy; PD: Pneumatic dilation; POEM: Peroral endoscopic myotomy; TIPS: Transjugular intrahepatic portosystemic shunt.
Um estudo sobre escolas eficazes no Brasil e na Itália: o que realmente importa na opinião dos pais, alunos, professores e gestores
Authors: Garcia Paulo Sergio , Bizzo Nelio 
Published: May 2017

Este estudo investiga os fatores escolares que explicam o desempenho acadêmico dos estudantes sob a visão dos grupos envolvidos no processo de formação: família, alunos, professores e gestores. Um estudo de caso, coletando dados por meio de entrevistas, foi realizado em duas escolas, uma no Brasil e outra na Itália, onde seus alunos apresentaram alto rendimento acadêmico. Os resultados revelaram que não há um fator isolado que explique o desempenho e, sim, múltiplos fatores, formando um campo magnético que sustenta e apoia a aprendizagem e o rendimento dos estudantes. Doze fatores na realidade brasileira e 11 na italiana foram citados por todos os grupos como explicativos do alto desempenho, sendo o principal fator o professor. Esses dados são relevantes para os especialistas, que podem utilizá-los em formação inicial e continuada, mas, sobretudo, para os gestores, utilizando-os na melhoria de suas escolas.
O novo status do saber na era tecnológica e os desafios para a educação segundo Hans Jonas
Authors: Oliveira Jelson Roberto de 
Published: May 2017

O objetivo do presente artigo é abordar a mudança no estatuto do saber a partir da era moderna e suas repercussões sobre a educação no século XXI, tendo como referência a filosofia de Hans Jonas. Para tanto, analisa-se como oconhecimento perdeu seu valor contemplativo, ontológica e politicamente falando, para assumir uma perspectiva de exploração do mundo, chegando a apresentar-se ele mesmo como uma mercadoria, na forma da informação. Contrapõe-se, assim, o homo faber ao homo sapiens, com o prejuízo do segundo. À educação cabe enfrentar a tensão entre o fazer e o saber, recusando uma visão simplista da ideia de competências e assumindo uma posição crítica capaz de preparar o ser humano integralmente para assumir a sua responsabilidade diante dos novos poderes da tecnologia.
PVDF-TrFE Electroactive Polymer Mechanical-to-Electrical Energy Harvesting Experimental Bimorph Structure
Authors: Kaval William G. , Lake Robert A. , Coutu Ronald A. 
Published: May 2017

AbstractResearch of electrostrictive polymers has generated new opportunities for harvesting energy from the surrounding environment and converting it into usable electrical energy. Electroactive polymer (EAP) research is one of the new opportunities for harvesting energy from the natural environment and converting it into usable electrical energy. Piezoelectric ceramic based energy harvesting devices tend to be unsuitable for low-frequency mechanical excitations such as human movement. Organic polymers are typically softer and more flexible therefore translated electrical energy output is considerably higher under the same mechanical force. In addition, cantilever geometry is one of the most used structures in piezoelectric energy harvesters, especially for mechanical energy harvesting from vibrations. In order to further lower the resonance frequency of the cantilever microstructure, a proof mass can be attached to the free end of the cantilever. Mechanical analysis of an experimental bimorph structure was provided and led to key design rules for post-processing steps to control the performance of the energy harvester. In this work, methods of materials processing and the mechanical to electrical conversion of vibrational energy into usable energy were investigated. Materials such as polyvinyledenedifluoridetetra-fluoroethylene P(VDF-TrFE) copolymer films (1um thick or less) were evaluated and presented a large relative permittivity and greater piezoelectric β-phase without stretching. Further investigations will be used to identify suitable micro-electromechanical systems (MEMs) structures given specific types of low-frequency mechanical excitations (10-100Hz).
INFLUENCE OF CONTACTOR CONTACT PRESSURE IN POWER CIRCUITS OF ELECTRIC STOCK ON THEIR PLASTIC DEFORMATION AND FUSING
Authors: Baliichuk O. Y. , Dubynets L. V. , Marenych O. P. , Ustymenko D. V. 
Published: May 2017

Purpose. The work is aimed at conducting the study to obtain the results that will quantify the influence of contactor contact pressure in power circuits of electric stock on the highest current value Id, that does not cause plastic deformation of contacts; and on the current value Ifs– incipient fusion of contacts taking into account the operation conditions. Therefore, such a study targeted to establish the contact fusing causes is relevant. Methodology. The paper proposes an engineering method for determining the currents Id and Ifs, taking into account the value of contact pressure, electrodynamic forces of contact repulsion Fe.d.r, as well as the pressure influence on the values of such forces. Findings. Taking the contactors 1SVAD8 (locomotive ChS8) and 7SP1 (locomotive ChS4) as an example, the authors conducted the calculations and found that the peak pressure force increases the currents Id and Ifs for these contactors by 11.8%; 15.5%; 11.8%; and 15.4% respectively (compared with the specified currents at the minimum pressure force). Influenced by Fe.d.r the pressure force of contacts for 1SVAD8 contactor decreased by 13.8…31.8%, and for 7SP1contactor the value Fe.d.r may be greater than the pressure force. This can lead to spontaneous shutdown of the closed contactor that is not provided by the control circuit. Ensuring during operation the maximum allowable pressure force of the contacts Fc slightly affects the value Fe.d.r, compared with the case when Fc has the minimum permissible value (in event of a fault in the heating circuit Fe.d.r for contactors 1SVAD8 and 7SP1 is reduced by only 2.45% and 2.59% respectively). Originality. The authors for the first time presented a quantitative assessment of influence of contactor contact pressure in power circuits of electric stock on their plastic deformation and fusing using the proposed engineering method. Practical value. The results obtained during the research allow solving the problem for developing measures aimed to improve the reliability of the heating circuits of electric locomotives ChS8 and ChS4. The proposed method of determining Id and Ifs can be used to quantify the influence of pressure of the main electric contacts mounted in power circuits of electric stock of all series, if during the operation there are cases of plastic deformation, fusing, welding of such contacts, in order to improve the reliability of power circuits.
Association of Pre-Chemotherapy Peripheral Blood Pro-Inflammatory and Coagulation Factors with Physical Function in Women with Breast Cancer
Authors: Yuan Yuan , Vora Nilesh , Sun Can-Lan , Li Daneng , Smith David , Mortimer Joanne , Luu The-Hang , Somlo George , Waisman James , Chao Joseph , Katheria Vani , Synold Timothy , Tran Vivi , Mi Shu , Feng Tao , Levi Abrahm , Arsenyan Anait , Choi Jennifer , Zavala Laura , Yost Susan , Hurria Arti 
Published: May 2017

Abstract

Background
Pro-inflammatory and coagulation factors serve as biomarkers of aging and functional reserve. The purpose of this study was to determine if pro-inflammatory (interleukin-6 [IL-6], C-reactive protein [CRP]), and coagulation (D-dimer) factors were associated with pre-chemotherapy functional status in women with stage I–III breast cancer.

Patients and Methods
Prior to chemotherapy initiation in patients with stage I–III breast cancer, the following was captured: IL-6, CRP, D-dimer blood levels, and physical function measures including activities of daily living (ADL, subscale of Medical Outcomes Study Physical Health); instrumental activities of daily living (IADL, subscale of the Older Americans Resources and Services Program); Timed Up and Go (TUG); physician-rated Karnofsky Performance Status (KPS); and self-rated KPS. The association of these biomarkers with physical function measures was evaluated.

Results
One hundred sixty patients (mean age 58.3 years, range 30–81 years) with stage I–III breast cancer (stages I [n = 34; 21.5%], II [n = 88; 55.7%], III [n = 36; 22.8%]) were enrolled. The group with poorest physical function (defined by ADL &lt;70, IADL &lt;14, and TUG ≥10 seconds) had higher levels of IL-6 (p = .05), D-dimer (p = .0004), and CRP (p = .05). There was no significant association between these biomarkers and KPS. Patients with at least two biomarkers in the highest quartile were more likely to have poorer physical function (odds ration [OR] 18.75, p &lt; .001). In multivariate analysis adjusting for age, stage, number of comorbidities, and body mass index, the association remained (OR 14.6, p = .002).

Conclusion
Pre-chemotherapy biomarkers of aging are associated with poorer physical function among patients with breast cancer across the aging spectrum. The Oncologist 2017;22:1189–1196
Attitudes Toward Cancer and Cancer Patients in an Urban Iranian Population
Authors: Badihian Shervin , Choi Eun-Kyung , Kim Im-Ryung , Parnia Aidin , Manouchehri Navid , Badihian Negin , Tanha Jila M. , Guallar Eliseo , Cho Juhee 
Published: May 2017

Abstract

Background
Because of the significant incidence and mortality of cancer in Iran, a Comprehensive National Cancer Control Program for the prevention and early detection of cancer was launched in 2007. However, cancer awareness and screening rates in Iran did not improve. This study aimed to evaluate public attitudes toward cancer and cancer patients in Iran.

Materials and Methods
We conducted a cross-sectional survey among 953 non-institutionalized individuals in Isfahan, Iran, from November 2014 to February 2015. We collected data on attitudes toward cancer in three domains (impossibility of recovery, cancer stereotypes, and discrimination), as well as questions on willingness to disclose a cancer diagnosis.

Results
Among all participants, 33.9% agreed that it is very difficult to regain one's health after a cancer diagnosis, 17.4% felt uncomfortable with a cancer patient, and 26.9% said that they would avoid marrying people whose family members had cancer. While 88.9% of study participants said that cancer patients deserve to be protected in society, 53.3% and 48.4% of participants agreed that they would not disclose a cancer diagnosis to neighbors and coworkers, respectively.

Conclusion
Negative attitudes with respect to impossibility of recovery and discrimination toward cancer and cancer patients were common among urban Iranians. Most people would not disclose a cancer diagnosis to others in spite of advancements in cancer diagnosis and treatment, reflecting unfavorable attitudes toward cancer and cancer patients in society. Successful implementation of cancer awareness and prevention programs in Iran may require social changes based on adequate information on cancer and cancer patients.
SÍNDROME DE BURNOUT EM DOCENTES DE UMA INSTITUIÇÃO DE ENSINO SUPERIOR
Authors: Ferreira Juliana Barros , Da Silva Karollyne Rocha , Silva  de Morais Karla Cavalcante , Souza Andréa Silva , De Almeida Cleyara Pereira 
Published: May 2017

Objetivos: Investigar a prevalência da síndrome de Burnout em professores de uma instituição particular, analisar a correlação entre Síndrome de Burnout e indicadores de qualidade de vida, e apresentar suas principais características. Método: Trata-se de um estudo observacional, de corte transversal e caráter quantitativo, com amostra de 93 indivíduos de ambos os gêneros, composta pelos docentes atuantes de uma instituição de ensino superior. Para a análise descritiva das características da população foram calculadas as médias e desvios padrão das variáveis estudadas. A correlação entre a qualidade de vida, fatores preditores, sinais e sintomas com a síndrome de Burnout foi realizada através do coeficiente de correlação de Spearman. O nível de significância adotado foi de 1%. Resultados: Dentre os participantes 5.38% evidenciaram a presença da síndrome e 15.91% exposição a mesma. Foi observado ainda que 34,4% apresentam altos níveis de exaustão emocional, 24,7% apresentam níveis altos de despersonalização e 34,4% apresentam baixos níveis de realização profissional. Conclusão: Os profissionais apontaram sinais de exaustão emocional condizentes com a Síndrome de Burnout em níveis altos, vinculados ao somatório das exigências da prática profissional. Os achados deste estudo podem subsidiar programas preventivos do adoecimento mental na prática da docência.
CULTURA ORGANIZACIONAL E ADOECIMENTO NO TRABALHO: UMA REVISÃO SOBRE AS RELAÇÕES ENTRE CULTURA, BURNOUT E ESTRESSE OCUPACIONAL
Authors: Aguiar Carolina Villa Nova , Silva Eliana Edington da Costa , Carvalho Bárbara Ribeiro de , Ferreira Jaqueline Cristina Muricy , Jesus Kaike Costa Oliveira de 
Published: May 2017

O presente trabalho propõe-se a realizar uma revisão narrativa da literatura nacional dos últimos 15 anos (entre os anos de 2000 e 2015) sobre as relações entre a cultura organizacional e dois conceitos intimamente relacionados ao adoecimento do trabalhador: o estresse ocupacional e o burnout. Para isso, foi realizado um levantamento bibliográfico por meio da consulta às bases de dados LILACS, PePSIC e SciElo. De forma complementar, foi consultado o banco de teses da CAPES. No total, foram contemplados oito trabalhos científicos, sendo cinco referentes às relações entre cultura e estresse ocupacional e três sobre as relações entre cultura e burnout. Os resultados apontam a escassez de estudos brasileiros sobre o tema. Ademais, um aspecto importante refere-se à dificuldade de articulação dos estudos, o que pode ser atribuído, em alguma medida, à utilização de diferentes ferramentas para a apreensão dos mesmos fenômenos. Apesar dos desafios gerados pelas inconsistências empíricas, foi possível identificar que a cultura organizacional configura-se como um preditor do desenvolvimento do estresse ocupacional e da síndrome de burnout. Acredita-se que o presente trabalho poderá contribuir para a elaboração de novas políticas e práticas organizacionais que prezem pela qualidade da cultura desenvolvida dentro do âmbito laboral.
PROBLEM-BASED LEARNING (PBL): A STRATEGY FOR TRAINING THE PSYCHOLOGIST AS A HEALTH PROFESSIONAL
Authors: Daltro Mônica Ramos , Ponde Milena Pereira 
Published: May 2017

There are about 49.412 of Psychologists acting on SUS, that challenges the education to move from its traditional positioning, that privileges clinics to create promoters of health. Part of a thesis that comprehend Psychology as health profession, this study describes Internship and pedagogic assisted practice , which the teacher is classified as a mediator, providing the perception of the students about the Internship experience. That descriptive study based on qualitative approach analyses the content of 51 questionnaires of students enrolled between the 8th and 10th semester of a Psychology course in Bahia, Brazil. The study was approved by the Ethics Committee (CAAE: 03670812.7.0000.5544). The data was analyzed by Sense Interpretation Method. The results indicate 100% of satisfaction facing the experience and development of competences as interdisciplinary attitude, capacity to work with teams, communication, autonomy and maturity. All of the above reveals the learning that integrates attitude, concept and techniques, answering the demands of the DCN’s and SUS.
Como criar e manter interações de qualidade em cursos online?
Authors: Correia Ana Paula 
Published: May 2017

Frequentemente em cursos online, os alunos participam em discussões que ocorrem em sistemas virtuais. Estas discussões online são muitas vezes atividades obrigatórias que contam para a nota final do curso. Mesmo que, em muitas ocasiões, os alunos considerem improdutiva a exigência de participar nestas discussões, eles participam na mesma por causa do peso que têm na avaliação final. Discussões online sem significado e de pouca qualidade são muitas vezes o resultado desta atividade. Um estudo de caso foi realizado com uma disciplina online de pós-graduação em tecnologia educativa em universidade nos Estados Unidos. Este curso oferece duas estratégias inovadoras para superar os desafios colocados pelas discussões online: (1) moderação de discussões facilitadas pelos colegas; (2) curadoria de conteúdos digitais. Este estudo de caso evidencia a eficácia destas estratégias e a possibilidade de as reusar, transferir para diferentes ambientes virtuais de aprendizagem e implementar em diferentes sistemas. Palavras-chave: Discussões online, Facilitação pelos colegas, Curadoria de conteúdos digitais. How to create and sustain high quality interactions in online courses?: The potential of peers moderation and digital curation AbstractParticipation in online discussions are often required from students while taking online classes. These are often mandatory activities that count towards the course final grade. Therefore, even though in many occasions online students find this requirement unproductive, they still participate with fear of lowering their grades. The results are often meaningless and superficial online conversations. A case study has been conducted with a postgraduate educational technology online course at a large university in the United States. This course offers two innovative strategies to overcome this issue: (1) peer facilitation, and (2) digital content curation. This case study offers evidence of these strategies effectiveness. This case study demonstrates the effectiveness of these strategies and the possibility of reusing them, transferring them to different virtual learning environments and implementing them in different systems. Keywords: Online discussions, Peer facilitation, Digital content curation.
Produção Colaborativa de REA para o Ensino de Línguas: da Interação à Coautoria
Authors: Costa Alan Ricardo , Leffa Vilson José 
Published: May 2017

O objetivo do texto é discutir o papel da interação entre autores e coautores de recursos educacionais abertos (REA) para o ensino e a aprendizagem de línguas. As discussões apresentadas partem de experiências vivenciadas em um curso de capacitação de professores de Espanhol como Língua Estrangeira (E/LE) para a produção e a adaptação de REA na web. Tal curso, ministrado na modalidade Educação a Distância (EaD), com duração de oito semanas e a realização de tarefas semanais de produção de recursos abertos via ferramenta Ensino de Línguas Online (ELO), possibilitou a seguinte observação: a interação é fundamental no trabalho com REA e na filosofia de colaboração, compartilhamento e coautoria subjacente a eles. Sem interação, os professores podem não entender aspectos essenciais de um recurso, como o objetivo de um dado REA disponível online e sua perspectiva teórica, o que pode dificultar sua apropriação e/ou adaptação. Além disso, sem interação, há um esvaziamento do potencial colaborativo dos REA, por não haver debate, crítica e reflexão conjunta sobre determinado material. Conclui-se que, em cursos de capacitação, a interação deve ser estimulada para um profícuo trabalho colaborativo e em rede com REA.Palavras-chave: Recursos educacionais abertos, Interação, Coautoria, Ensino de línguas online. Collaborative Production of OER for the Teaching of Languages: from Interaction to Co-authorship AbstractThe purpose of this text is to discuss the role of interaction between authors and co-authors of Open Educational Resources (OERs) for teaching and learning languages. The present discussions are based on experiences from a training course on production and adaptation of OERs on the Web for Spanish as a Foreign Language teachers. This course, taught at a Distance, in a period of eight weeks and with the accomplishment of weekly tasks, producing open resources with an Online Teaching Language tool has allowed the following observations: interaction is fundamental to the work with OERs and to the philosophy of collaboration, sharing and co-authorship underlying them. Without interaction, teachers may not understand essential aspects of a resource, such as the objective of a specific OER available online and its theoretical perspective, which may make its appropriation and/or adaptation more difficult. In addition, without interaction, there is a depletion of the collaborative potential of the OERs, because there is no debate, criticism and joint reflection on a specific material. It is concluded that, in training courses, the interaction should be stimulated, for a productive collaborative work with OERs.Keywords: Open Educational Resources, Interaction, Co-authorship, Online Language Teaching.