bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements
Authors: Andermann Tobias , Fernandes Alexandre M. , Olsson Urban , Töpel Mats , Pfeil Bernard , Oxelman Bengt , Aleixo Alexandre , Faircloth Brant C. , Antonelli Alexandre 
Published: January 2018

AbstractAdvances in high-throughput sequencing techniques now allow relatively easy and affordable sequencing of large portions of the genome, even for non-model organisms. Many phylogenetic studies reduce costs by focusing their sequencing efforts on a selected set of targeted loci, commonly enriched using sequence capture. The advantage of this approach is that it recovers a consistent set of loci, each with high sequencing depth, which leads to more confidence in the assembly of target sequences. High sequencing depth can also be used to identify phylogenetically informative allelic variation within sequenced individuals, but allele sequences are infrequently assembled in phylogenetic studies.Instead, many scientists perform their phylogenetic analyses using contig sequences which result from thede novoassembly of sequencing reads into contigs containing only canonical nucleobases, and this may reduce both statistical power and phylogenetic accuracy. Here, we develop an easy-to-use pipeline to recover allele sequences from sequence capture data, and we use simulated and empirical data to demonstrate the utility of integrating these allele sequences to analyses performed under the Multispecies Coalescent (MSC) model. Our empirical analyses of Ultraconserved Element (UCE) locus data collected from the South American hummingbird genusTopazademonstrate that phased allele sequences carry sufficient phylogenetic information to infer the genetic structure, lineage divergence, and biogeographic history of a genus that diversified during the last three million years. The phylogenetic results support the recognition of two species, and suggest a high rate of gene flow across large distances of rainforest habitats but rare admixture across the Amazon River. Our simulations provide evidence that analyzing allele sequences leads to more accurate estimates of tree topology and divergence times than the more common approach of using contig sequences.
Hematopoietic stem cells differentiate into restricted myeloid progenitors before cell division
Authors: Grinenko Tatyana , Eugster Anne , Thielecke Lars , Ramazs Beata , Krueger Anja , Dietz Sevina , Glauche Ingmar , Gerbaulet Alexander , Bonin Malte von , Basak Onur , Clevers Hans , Chavakis Triantafyllos , Wielockx Ben 
Published: January 2018

SummaryHematopoietic stem cells (HSCs) continuously replenish all blood cell types through a series of differentiation steps that involve the generation of lineage-committed progenitors as well as necessary expansion due to repeated cell divisions. However, whether cell division in HSCs precedes differentiation is unclear. To this end, we used an HSC cell tracing approach and Ki67RFP knock-in mice to assess simultaneously divisional history, cell cycle progression, and differentiation of adult HSCs in vivo. Our results reveal that HSCs are able to differentiate into restricted progenitors, especially common myeloid progenitors, restricted megakaryocyte-erythroid progenitors (PreMEs) and pre-megakaryocyte progenitors (PreMegs), without undergoing cell division and even before entering the S phase of the cell cycle. Additionally, the phenotype of the undivided but differentiated progenitors correlated with expression of lineage-specific genes that manifested as functional differences between HSCs and restricted progenitors. Thus, HSC fate decisions appear to be uncoupled from physical cell division. Our results facilitate a better understanding of the mechanisms that control fate decisions in hematopoietic cells. Our data, together with separate findings from embryonic stem cells, suggest that cell division and fate choice are independent processes in pluripotent and multipotent stem cells.
Use of hashtags to retrieve information on the web
Authors: Buarki Hanadi , Alkhateeb Bashaer 
Published: January 2018

Purpose
This paper aims to find out how people use hashtags as a medium of information retrieval and dissemination, and how they are used in social media tools, such as Instagram.

Design/methodology/approach
A quantitative question estimated the participants’ use of the hashtags during the workshop. Statistical data of the participants and their posts were collected from social network analysis tools. The posts that included the workshop’s designated hashtags were retrieved, recorded, coded and analysed to collect qualitative data.

Findings
In total, 74 (46 per cent) participants used the workshop’s hashtags to share posts, the retrieval of the hashtags declined by time and Google search engine retrieved the maximum results. It was found that a hashtag would be common when associated with descriptors, and that its use depends on its popularity, followers and its survival time. Finally, hashtags connect people, allow them to express their enthusiasm to reveal common interests and networks them through social media tools such as Instagram.

Research limitations/implications
The research limitations were in relation to the participants’ demographic information, the non-identification of their gender and hashtags being misspelt.

Practical implications
The research project summarises the experiences that social media has made connecting easier through the right use of hashtags by providing 24/7 free feedback, the possibility to exchange ideas and by their involvement in promoting and organising events. It also indicates interaction among people sharing the same interest by retrieving subject-based hashtags.

Originality/value
When retrieving information related to hashtags, it is recommended that multi-retrieval systems, social media tools and search engines should be consulted and not depend on a solo system or tool. Future research is recommended in search for a multi-retrieval social media and search engine tool that standardises the use of hashtags and will retrieve information from different platforms.
Instructor and peer influence on college student use and perceptions of Wikipedia
Authors: Garrison John C. 
Published: January 2018

Purpose
This study aims to investigate how undergraduate students are influenced by instructors and peers in the ways that they use and think about Wikipedia for academic work. It examines the positive (encouraging the use of Wikipedia) and negative (discouraging the use of Wikipedia) influences of others and how these affect student behavior and attitudes.

Design/methodology/approach
Sixteen undergraduates participated in two meetings each with the principal investigator, each meeting consisting of a structured interview and a brief survey. Recorded interviews were analyzed by the investigator for patterns to compare participants’ responses.

Findings
Participants were more frequently and strongly influenced by instructors than by peers about Wikipedia, and this influence was for the most part perceived to be negative. However, the ways in which student behaviors and attitudes changed in response to this influence varied. Three categories or “influence types” emerged in the ways influence was manifested: receptive, independent and conflicted.

Practical implications
The findings of this study will aid instructors of undergraduate students by describing the likely reactions of those students to various ways of talking about Wikipedia. This information can help inform methods for teaching different kinds of students about the website.

Originality/value
Previous studies have shown how students use Wikipedia, as well as the attitudes of faculty toward Wikipedia. This study serves to bridge the gap between these areas, providing insight into how faculty and classmates’ attitudes influence student use of Wikipedia.
An author co-citation analysis of 37 years of iMetrics
Authors: Khasseh Ali Akbar , Soheili Faramarz , Mousavi Chelak Afshin 
Published: January 2018

Purpose
This research aims to examine the intellectual structure of iMetrics through author co-citation analysis.

Design/methodology/approach
This research uses common techniques in bibliometrics and social network analysis. It analyses 5,944 records from the Web of Science in the field of iMetrics that are published between 1978 and 2014.

Findings
Findings indicated that researchers including “Garfield”, “Egghe”, “Glanzel”, “Leydesdorff” and “Price” have received many co-citations. The author co-citation analysis in iMetrics resulted in eight thematic clusters, including “theoretical foundations and citation analysis”, “sociology of science”, “science mapping and visualization”, “network analysis”, “classic laws of bibliometrics”, “webometrics”, “technometrics” and “miscellaneous”. “Theoretical foundations and citation analysis” is the biggest cluster which comprises 59 authors. The results suggest the crucial role of price medallists in shaping the intellectual structure of knowledge in iMetrics.

Originality/value
Extracting the patterns embedded in the knowledge structure of iMetrics studies provides beneficial information for both researchers and policymakers. This research study is valuable that used an appropriate set of records regarding both recall and precision. Furthermore, this study helps us better understand the characteristics of iMetrics, its subject areas, and the prominent authors in those areas.
Cybersecurity and information security – what goes where?
Authors: von Solms Basie , von Solms Rossouw 
Published: January 2018

Purpose
The purpose of this paper is to define cybersecurity and cybersecurity governance in simplified terms – to explain to the boards of directors and executive management their responsibilities and accountabilities in this regard.

Design/methodology/approach
The primary research methodology utilized in this paper is desk research. A literature study is followed by some discussion in terms of the contribution made.

Findings
Clearly define the relationship between cybersecurity and information security, especially from a governance perspective.

Research limitations/implications
The paper is based predominantly on an ISO standard.

Originality/value
The simplification of terminology to be used in the governance of cybersecurity, together with assistance to the guiding of boards of directors regarding their duties and responsibilities as far as cybersecurity is concerned.
A process model for implementing information systems security governance
Authors: Nicho Mathew 
Published: January 2018

Purpose
The frequent and increasingly potent cyber-attacks because of lack of an optimal mix of technical as well as non-technical IT controls has led to increased adoption of security governance controls by organizations. The purpose of this paper, thus, is to construct and empirically validate an information security governance (ISG) process model through the plan–do–check–act (PDCA) cycle model of Deming.

Design/methodology/approach
This descriptive research using an interpretive paradigm follows a qualitative methodology using expert interviews of five respondents working in the ISG domain in United Arab Emirates (UAE) to validate the theoretical model.

Findings
The findings of this paper suggest the primacy of the PDCA Deming cycle for initiating ISG through a risk-based approach assisted by industry-wide best practices in ISG. Regarding selection of ISG frameworks, respondents preferred to have ISO 27K supported by NIST as the core framework with other relevant ISG frameworks/standards forming the peripheral layer. The implementation focus of the ISG model is on mapping ISO 27K/NIST IT controls relevant IT controls selected from ISG frameworks from a horizontal and vertical perspective. Respondents asserted the automation of measurement and control mechanism through automation to assist in the feedback loop of the PDCA cycle.

Originality/value
The validated model helps academics and practitioners gain insight into the methodology of the phased implementation of an information systems governance process through the PDCA model, as well as the positioning of ITG and ITG frameworks in ISG. Practitioners can glean valuable insights from the empirical section of the research where experts detail the success factors, the sequential steps and justification of these factors in the ISG implementation process.
Employee fraud and misconduct: empirical evidence from a telecommunication company
Authors: Nawawi Anuar , Salin Ahmad Saiful Azlin Puteh 
Published: January 2018

Purpose
The purpose of this study is to examine whether policies and procedures, one of the fundamental elements in the internal control environment, are adequate and effective in preventing fraud and unethical practices committed by employees of a company. In addition, this study attempts to assess the awareness and understanding of employees on the existence of relevant company policies and standard operating procedures for internal fraud and misconduct deterrence.

Design/methodology/approach
Five cases from one Malaysian telecommunication company were randomly selected as a case study. Content analyses were conducted on actual cases of internal fraud and wrongdoings that were investigated and the enforcement that was discharged by the company.

Findings
This study found that the company has sufficient policies and standard operating procedures to curb internal fraud and wrongdoing. However, they are ineffective and malfunction when responsible personnel violate or override the policies and procedures, irrespective of whether this is caused by carelessness, poor knowledge or clear intention to act dishonestly.

Research limitations implications
This study was conducted on only one company with a limited number of investigated fraud cases. Access to higher number of fraud cases, particularly those that involved large amount of losses and considered as high-profile cases, were denied because of confidentiality.

Practical implications
The study found that weak compliance to internal controls provides opportunities for fraud to occur, consistent with the fraud triangle theory. Fraud, committed both outside and inside an organization, can be considered as a worrying problem in the organization because of its severe impact on the reputation and bottom line figures of the company. The study provides important information to management to strengthen their compliance with the internal control system generally and policies and procedures particularly.

Originality/value
This study is original, as it focuses on the actual fraud cases that occur in the telecommunication industry, which is under-researched in fraud literature, particularly in developing markets such as Malaysia. Prior empirical research on fraud and unethical practices has concentrated on factors that contribute to fraud and the financial and non-financial impacts of fraud in an organization.
Implementation of a nationwide electronic health record (EHR)
Authors: Fragidis Leonidas L. , Chatzoglou Prodromos D. 
Published: January 2018

Purpose
The purpose of this paper is to identify the best practices applied during the implementation process of a national electronic health record (EHR) system. Furthermore, the main goal is to explore the knowledge gained by experts from leading countries in the field of nationwide EHR system implementation, focusing on some of the main success factors and difficulties, or failures, of the various implementation approaches.

Design/methodology/approach
To gather the necessary information, an international survey has been conducted with expert participants from 13 countries (Denmark, Austria, Sweden, Norway, the UK, Germany, the Netherlands, Switzerland, Canada, the USA, Israel, New Zealand and South Korea), who had been playing varying key roles during the implementation process. Taking into consideration that each system is unique, with each own (different) characteristics and many stakeholders, the methodological approach followed was not oriented to offer the basis for comparing the implementation process, but rather, to allow us better understand some of the pros and cons of each option.

Findings
Taking into account the heterogeneity of each country’s financing mechanism and health system, the predominant EHR system implementation option is the middle-out approach. The main reasons which are responsible for adopting a specific implementation approach are usually political. Furthermore, it is revealed that the most significant success factor of a nationwide EHR system implementation process is the commitment and involvement of all stakeholders. On the other hand, the lack of support and the negative reaction to any change from the medical, nursing and administrative community is considered as the most critical failure factor.

Originality/value
A strong point of the current research is the inclusion of experts from several countries (13) spanning in four continents, identifying some common barriers, success factors and best practices stemming from the experience obtained from these countries, with a sense of unification. An issue that should never be overlooked or underestimated is the alignment between the functionality of the new EHR system and users’ requirements.
A multi-objective multicast routing optimization based on differential evolution in MANET
Authors: Wei Wenhong , Qin Yong , Cai Zhaoquan 
Published: January 2018

Purpose
The purpose of this paper is to propose a multi-objective differential evolution algorithm named as MOMR-DE to resolve multicast routing problem. In mobile ad hoc network (MANET), multicast routing is a non-deterministic polynomial -complete problem that deals with the various objectives and constraints. Quality of service (QoS) in the multicast routing problem mainly depends on cost, delay, jitter and bandwidth. So the cost, delay, jitter and bandwidth are always considered as multi-objective for designing multicast routing protocols. However, mobile node battery energy is finite and the network lifetime depends on node battery energy. If the battery power consumption is high in any one of the nodes, the chances of network’s life reduction due to path breaks are also more. On the other hand, node’s battery energy had to be consumed to guarantee high-level QoS in multicast routing to transmit correct data anywhere and at any time. Hence, the network lifetime should be considered as one objective of the multi-objective in the multicast routing problem.

Design/methodology/approach
Recently, many metaheuristic algorithms formulate the multicast routing problem as a single-objective problem, although it obviously is a multi-objective optimization problem. In the MOMR-DE, the network lifetime, cost, delay, jitter and bandwidth are considered as five objectives. Furthermore, three QoS constraints which are maximum allowed delay, maximum allowed jitter and minimum requested bandwidth are included. In addition, we modify the crossover and mutation operators to build the shortest-path multicast tree to maximize network lifetime and bandwidth, minimize cost, delay and jitter.

Findings
Two sets of experiments are conducted and compared with other algorithms for these problems. The simulation results show that our proposed method is capable of achieving faster convergence and is more preferable for multicast routing in MANET.

Originality/value
In MANET, most metaheuristic algorithms formulate the multicast routing problem as a single-objective problem. However, this paper proposes a multi-objective differential evolution algorithm to resolve multicast routing problem, and the proposed algorithm is capable of achieving faster convergence and more preferable for multicast routing.
A hybrid particle swarm optimization algorithm for the capacitated location routing problem
Authors: Kechmane Laila , Nsiri Benayad , Baalal Azeddine 
Published: January 2018

Purpose
The purpose of this paper is to solve the capacitated location routing problem (CLRP), which is an NP-hard problem that involves making strategic decisions as well as tactical and operational decisions, using a hybrid particle swarm optimization (PSO) algorithm.

Design/methodology/approach
PSO, which is a population-based metaheuristic, is combined with a variable neighborhood strategy variable neighborhood search to solve the CLRP.

Findings
The algorithm is tested on a set of instances available in the literature and gave good quality solutions, results are compared to those obtained by other metaheuristic, evolutionary and PSO algorithms.

Originality/value
Local search is a time consuming phase in hybrid PSO algorithms, a set of neighborhood structures suitable for the solution representation used in the PSO algorithm is proposed in the VNS phase, moves are applied directly to particles, a clear decoding method is adopted to evaluate a particle (solution) and there is no need to re-encode solutions in the form of particles after applying local search.
A Quantum-behaved Pigeon-Inspired Optimization approach to Explicit Nonlinear Model Predictive Controller for quadrotor
Authors: Xian Ning , Chen Zhilong 
Published: January 2018

Purpose
The purpose of this paper is to simplify the Explicit Nonlinear Model Predictive Controller (ENMPC) by linearizing the trajectory with Quantum-behaved Pigeon-Inspired Optimization (QPIO).

Design/methodology/approach
The paper deduces the nonlinear model of the quadrotor and uses the ENMPC to track the trajectory. Since the ENMPC has high demand for the state equation, the trajectory needed to be differentiated many times. When the trajectory is complicate or discontinuous, QPIO is proposed to linearize the trajectory. Then the linearized trajectory will be used in the ENMPC.

Findings
Applying the QPIO algorithm allows the unequal distance sample points to be acquired to linearize the trajectory. Comparing with the equidistant linear interpolation, the linear interpolation error will be smaller.

Practical implications
Small-sized quadrotors were adopted in this research to simplify the model. The model is supposed to be accurate and differentiable to meet the requirements of ENMPC.

Originality/value
Traditionally, the quadrotor model was usually linearized in the research. In this paper, the quadrotor model was kept nonlinear and the trajectory will be linearized instead. Unequal distance sample points were utilized to linearize the trajectory. In this way, the authors can get a smaller interpolation error. This method can also be applied to discrete systems to construct the interpolation for trajectory tracking.
International leadership for the control of disease outbreaks relating to “One Health”
Authors: Plianbangchang Samlee 
Published: January 2018

Purpose
In view of the current global challenge of infectious diseases transmitted from animal to man, this is a complimentary piece of paper to promote, in particular, the inter-sectorial and multi-disciplinary coordination and cooperation in their prevention and control, among all concerned agencies/organizations at both policy and operational levels, with special emphasis on the importance of leadership development within the socio-cultural context of health, and with particular reference to the concept of “One Health” that implies the intimate interaction between man and animal within their own environments/ecosystems. The paper aims to discuss these issues.

Design/methodology/approach
This is a commentary piece.

Findings
The paper directly and indirectly suggests lacunae in several areas of concern for further research and development to fill the knowledge gap in such a prevention and control.

Originality/value
This is a commentary piece.