bluuebunny/crossref_metadata_2025_split huggingface dataset:
Choosing a promotion channel for a startup project in the modern media space
Authors: Kryzhanovskaya O. A. 
Published: October 2024

Relevance. The startup market is becoming increasingly saturated. Effective promotion channels allow you to stand out from the competition and attract the attention of the target audience. Startups often work with a limited budget. Optimizing the choice of promotion channels is critical to maximizing the return on investment. Modern media management covers many platforms (social networks, blogs, video hosting, etc.). Choosing the right channel helps to optimally use resources and ensure maximum visibility. Different channels are suitable for different target groups. An effective choice of promotion channel helps to more accurately reach the desired audience, taking into account its preferences and behavior. Consumers are increasingly paying attention to digital communication channels. Taking into account current trends and preferences allows you to improve interaction with the audience. The influence of social networks and bloggers is becoming an important mechanism for creating trust among consumers. This can significantly increase the recognition of a startup. All this emphasizes the importance of a strategic approach to choosing promotion channels for a successful launch and sustainable growth of a startup project in the modern media landscape.The purpose of the study is to choose a promotion channel for a startup project in the modern media space.Objectives: to substantiate the relevance of choosing a promotion channel for a startup in the modern media space; to study the demand and effectiveness of modern promotion channels; to use in practice the method of multicriteria selection of promotion channels for a startup project; to substantiate the results obtained.Methodology. The research methodology is based on the methods of comparison and comparison, deduction and induction, qualitative and quantitative analysis, as well as the Churchman-Ackoff multi-criteria assessment method.Results. The study substantiates the relevance of choosing a promotion channel for a startup in the modern media space; the demand and effectiveness of modern promotion channels are studied; the method of multi-criteria selection of channels for promoting a startup project was used in practice; the obtained results were substantiated.Conclusions. The effectiveness of the selected channels for promoting a startup project in the modern media space was proven as conclusions.
UN Assistance to African countries in building climate-resilient agriculture
Authors: Kuzmina V. M. , Parkhomchuk M. A. 
Published: October 2024

Relevance. Africa is the mirror and quintessence of modern international processes. The continent faces a gigantic number of challenges, some of an existential nature. But at the same time, there is an active search for ways to solve them.The purpose is to consider the experience of forming climate-resilient agriculture on the example of individual African countries and the role of the UN in this process.Objectives: to characterize the conditions and reasons for the formation of climate-resilient agriculture in the African region; assess the policies of the governments of Kenya, Tanzania, Ethiopia, and Rwanda on the development of climate-resilient agriculture.Methodology. The comparative research method was used in the study of agricultural development programs in African countries. Chronological and historical methods of studying legal documents, programs of the United Nations, FAO, NEPAD, Kenya, Tanzania, Ethiopia, Rwanda aimed at the formation of climate-resilient agriculture. A statistical research method for operating with data from the statistical databases of Globaleconomy and the World Health Organization.Results. The introduction of new technologies in agriculture is a condition for saving the environment, which is under pressure from two sides: global climate change and unprecedented growth in the population and its needs. One of the most important areas is to increase the productivity of agriculture, the solution of this urgent task will depend on the introduction of new technologies: seeds, fertilizers, irrigation, plant protection, etc.Conclusions. The introduction of programs and technologies for the formation of climate-resilient agriculture in African countries requires significant funding and institutional and legal preparation.
HR-brand: features of formation and development
Authors: Polischuk O. A. , Gracheva N. A. , Isaev P. A. , Fedorinov A. V. 
Published: October 2024

Relevance. The development of HR management stems from the need for organizations to attract and retain highly qualified employees in the competitive environment of the modern labor market. HR branding is a strategy based on the formation and support of a positive image of the company in the eyes of employees, as well as the company's commitment to the principles and values that bind employees and the organization. Positive evaluations of the organization's employees and their recommendations can attract new specialists and strengthen the company's reputation as a reliable and attractive employer.The purpose of the article is to study a special category of reputation and perception of the company – the HR brand.Objectives: to study the conditions for building an HR brand, its structure and key elements; to consider the history of the origin of the idea of HR branding; to assess the interest in creating a special reputation in the field of human resource management; to justify why it is impossible to build an EVP (employer's value proposition) without HR branding.Methodology. In the course of scientific research, empirical, theoretical, statistical methods and methods of graphical representation were used.Results: the theoretical aspects of building a company's HR brand were studied; the popularity of this topic in science and business was shown. A set of knowledge about the features of HR branding in the Russian and foreign markets has been formed and the prospects for the development of this area are shown. It shows why it is important to work on an HR brand and how to start forming a positive image of the company, its reputation and prestige.Conclusions. The article emphasizes the relevance and importance of the topic under consideration, taking into account the latest trends, prerequisites and prospects for new companies. The possibilities that open up for an employer when forming an original and popular HR brand are considered.
Modern information technologies for studying the cost of working time as an important tool for effective management of business processes
Authors: Kopteva Zh. Yu. , Tomakova I. A. , Sadikov R. A. 
Published: October 2024

Relevance. In the context of economic, social and socio-political changes, growth and increased competition, it is becoming increasingly interesting to study the issues of scientific organization and labor rationing, as well as factors affecting labor productivity, and, ultimately, the effectiveness and profitability of production processes in general. There is an objective need to improve not only the methods of managing the cost of working time, but also to skillfully apply modern digital technologies. That is why it is so important to develop and modify, in accordance with the requirements of the market environment, methods, tools and methods of analysis using artificial intelligence (AI) when studying the cost of working time of employees of an organization.The purpose is based on the study of theoretical and methodological approaches to improving the system of organization and rationing of labor, to provide a scientific justification for the relevance of the development of the processes of accounting for working hours of employees of the organization through the integration of modern information technologies.Objectives: to analyze the existing approaches to the organization and rationing of labor; to identify the potential of integrating modern information technologies into the processes of working time accounting; to develop practical recommendations for improving the system of accounting for the working hours of employees of the organization using modern information technologies.Methodology. The theoretical and practical basis for the study of modern approaches to the modernization of the system of organization and rationing of labor at the enterprise were the methods of analyzing literary sources, statistical data, expert assessments, as well as using an integrated approach.Results. The result of the research in the work is a comprehensive analysis of the use of artificial intelligence (AI) in studying the cost of working time to modify the processes of rationing labor functions through the integration of information technologies.Conclusions. In the course of the study, we proved the positive effect of the introduction of modern information technology systems at the enterprise, as well as scientifically substantiated the relevance of the development of processes for analyzing the cost of working time and rationing employees of enterprises through the integration of modern information technologies.
The influence of reflexive modernity on the change of human capital
Authors: Komornikova O. M. 
Published: October 2024

Relevance is due to the need to revise approaches to the theoretical understanding of the concept of "human capital" in modern society, since it is considered as a resource for the development of society, solving many current social problems, as well as confronting new risks. The concept of "reflexivity" as a social phenomenon also needs conceptual development. It is also necessary to identify the relationships between these phenomena.The purpose is to consider how the content of the phenomenon of human capital is transformed in the conditions of the formation of the socio-cultural structure of the information society, including the growing reflexivity of social interaction.Objectives: to identify the key features of understanding the phenomenon of reflexivity (reflection) in philosophy, psychology, sociology; the specifics of this phenomenon in the context of the formation of the information society, as well as the impact of this process on the content component of human capital in modern society.Methodology. The author relies on the achievements of related sciences in the field of the study of reflexivity. The analysis of the problem is based on the ideas and principles of systemic, synergetic, activity-based approaches, as well as the provisions of the theories of emergent effects and human capital.Results. The article substantiates the idea that the transition to a new type of social organization, accompanied by the appearance of new characteristics in the social system, led to the development and strengthening of the importance of reflexivity of society. At the same time, the requirements for the individual are changing and the content of human capital is being revised. This process is conditioned by the need to increase awareness, objectivity of ideas about the system of social relations in conditions of expanding individual freedom, its role in social processes, increasing the volume of information produced by society and the subjects involved in this process.Conclusions. Reflexivity as a characteristic of the social system appears at the later stages of the development of society. The basis of its formation was the evolution of psychological processes in humans and a qualitative change in the organization of society. On the one hand, there is an expansion of the potential of the individual and society, on the other ‒ the risks they have to face. Objectively the content of human capital is expanding, and social demands on it are growing. The ability to reflect seems to be an integral part of it. It involves the mastery of a person's ways of thinking and intellectual techniques for perceiving processes and events in society, which was previously the lot of the elite; internalization, rather than declaring universal values.
About the characteristic features of Russians (territorial and settlement aspect)
Authors: Lebedeva L. G. 
Published: October 2024

Relevance. In the post-Soviet era, changes in the consciousness and behavior of the masses of people became inevitable. The study of the structure of characteristic features (consciousness and behavior) of Russians (both positive and negative) in modern conditions is of great scientific and practical interest.The purpose is to use sociological materials to identify the hierarchical structure of characteristic positive and negative traits (consciousness and behavior) of Russians, including by territorial settlement groups.Objectives: to analyze the assessments of positive and negative traits inherent, in the opinion of respondents, to people of their generation; to identify their hierarchical structure and characteristics by territorial settlement groups.Methodology. The sociological survey and the sampling method, methods of grouping data, their analysis and generalization, and correlation analysis were used.Results. The leading features (both positive and negative) inherent, in the opinion of respondents, to people of their generation are revealed, as well as the relationships between them by territorial settlement groups are revealed.Conclusions. The positive features that have taken the leading places indicate the high potential of humanism and harmonious personality development among the majority of Russians. The negative traits that took the leading places indicate a relatively low level of sociality, social empathy and social responsibility of significant masses of people (according to respondents' estimates). However, the respondents' overall assessment of people of their generation is predominantly positive, which gives grounds for social optimism. At the same time, although the differences between territorial settlement groups in both positive and negative features are not antagonistic, they can be the basis for elements of contradictions and conflicts. Consistent active work of advanced social forces is necessary, first of all, by means of education to strengthen the positive traits of people as a "situationally dominant factor" and a center of attraction, a positive pole, especially for the younger generations.
Substantive behavioral aspects of consumer behavior in the conditions of sanctions pressure on the Russian economy
Authors: Polozhentseva Yu. S. , Logvinova I. O. 
Published: October 2024

Relevance. Sanctions pressure on the economy of the Russian Federation is one of the most important factors influencing consumer behavior and their consumer preferences. Under sanctions, many social, economic and political aspects influence consumer behavior, from which new consumer trends and changes in consumer behavior emerge.The purpose is to explore the substantive behavioral aspects of consumer behavior under the conditions of sanctions pressure on the Russian economy.Objectives: study changes in consumer preferences in connection with global crises; analyze changes in consumer behavior depending on various factors and price dynamics as a factor in consumer behavior; explore the influence of cognitive distortions on the meaningful behavioral aspects of consumers; propose the concept of business company plans in accordance with new consumer expectations.Methodology. In the process of research, general scientific methods of logical and statistical analysis, field research, as well as qualitative and quantitative analysis were used. Results. The survey showed that consumers have become more frugal and choose domestic brands in order to save money, the study of the impact of cognitive distortions on consumers showed that society is prone to a pessimistic attitude in terms of adopting new domestic products and brands.Conclusions. A business plan under sanctions pressure, aimed at the novelty of the product and its effectiveness, will help companies promote their goods and services on the Russian market during the period of sanctions pressure. Focusing on changing the object of purchase, place of purchase (online trading if possible), timing and methods of procurement in accordance with new motives and customer expectations will give companies an advantage in conditions of market instability and changing behavioral aspects of consumers.
Stages of development of a methodological approach for assessing the effectiveness of digital transformation projects of an industrial enterprise
Authors: Babkin A. V. , Tashkinov A. G. 
Published: October 2024

The relevance of the study is determined by the fact that the digital transformation of the enterprise becomes the cornerstone of the organization's success: enterprises use digital technologies to optimize production processes, logistics operations, improve product quality, customer service and develop digital innovation.The purpose of the study is to develop key stages of the formation of a methodological approach to assess the effectiveness of digital transformation projects of an industrial enterprise based on the determination of the main aspects of digital transformation of enterprises in terms of the formation of a new business model of the enterprise in a single information (digital) space.The objectives of the study are to analyze publications in terms of clarifying the term "digital transformation project of an industrial enterprise" and formulating the author's definition of "digital transformation project of an industrial enterprise" from the standpoint of developing the production and economic system; identification of distinctive features of IT projects and projects of digital transformation of an industrial enterprise; analysis of the tools for assessing management digital decisions; development of stages of methodological approach formation for evaluation of efficiency of digital transformation projects.Methodology. The following methods were used during the study: comparative analysis, observations, generalization, abstraction, modeling. In the course of scientific research, methods of deduction and induction, systemic and critical analysis were used.Results. As a result of the study, the authors formulated the definition of the definition "project of digital transformation of an industrial enterprise" from the standpoint of developing the production and economic system. Distinctive features of IT projects and digital transformation projects of an industrial enterprise have been identified. Based on the proposed structure of the methodological approach and the analysis of tools for assessing management digital decisions, the stages of forming a methodological approach for assessing the effectiveness of digital transformation projects of an industrial enterprise were developed.Conclusion. The authors conclude that the developed stages of forming a methodological approach to assess the effectiveness of digital transformation projects of an industrial enterprise will be useful for enterprise managers to ensure strategic competitive success and increase operational efficiency.
Tracing proliferating potential of lung tumours by [11C]Nicotinamide
Authors: Bielik Robert , Brown Gavin , Solovyev Dmitry , Lewis David 
Published: October 2024

Many tumours rely on aerobic glycolysis, known as the Warburg effect, to satisfy energy needs and sustain rapid proliferation [1]. High demands of glucose in tumours can be measured by [18F[fluorodeoxyglucose, [18F]FDG, positron emission tomography (PET). Nicotinamide adenine dinucleotide (NAD) is a coenzyme involved in redox reactions in many metabolic pathways, including glycolysis. To maintain the high rates of glycolysis and proliferation, tumours need increased NAD+ levels and use nicotinamide for the upregulated NAD+ salvage pathway that is the main source of NAD+ in proliferative cancer cells [2]. Herein, we show an improved synthesis method of [11C]Nicotinamide, [11C]NAM, and studied the uptake of [11C]NAM and [18F]FDG to measure proliferating capacity in a lung cancer model.
[Carboxyl-11C]nicotinamide was synthesized by a one-pot radiolabeling method [3] on the SYNTHRA synthesizer (Synthra GmbH, Germany) (see Figure 1A). We used a KrasG12D/+ genetically engineered mouse model of lung cancer and evaluated the uptake of [11C]nicotinamide and [18F]FDG with dual-tracer sequential imaging protocol (see Figure 1B) using a NanoScan PET/MRI scanner (Mediso Medical Imaging Systems, Hungary).
We obtained [carboxyl-11C]nicotinamide in a radiochemical yield of 15 ± 5 %, volumic activity of 50 ± 10 MBq/ml, and radiochemical purity was > 99 %. We optimized the imaging protocol and found the uptake of [11C]nicotinamide co-localized with the uptake of [18F]FDG in the KrasG12D/+ model of lung cancer as shown in Figure 1C suggesting the higher NAM uptake was associated with high NAD+ production in highly proliferating tumours.
We demonstrated that metabolic PET/MRI imaging with [11C]NAM can complement [18F]FDG PET and be useful for probing proliferative potential in lung cancer. This method could be translated and applied in clinical practice to enable visualization of NAD+ metabolism in lung tumours and targeted therapeutically.
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Automated segmentation pipeline for segmentation and characterising metabolic dysregulation in cancer cachexia
Authors: Duff Lisa , Brown Emma , Edgar Fraser , Pires Manuel , Sundar Lalith Kumar Shiyam , Solovyev Dmitry , Lewis David 
Published: October 2024

Cancer cachexia disrupts metabolic homeostasis across various organs. Positron Emission Tomography (PET) is valuable for investigating cachexia in preclinical models and patients[1]. However, manually segmenting multiple organs is laborious and hinders quantitative analysis of whole-body PET. This study establishes an automated pipeline for segmenting and characterizing organs in preclinical PET/MRI.
Acute metabolic changes were induced in non-tumour bearing mice through three approaches: a single dose of Growth Differentiation Factor-15 (GDF-15; n=3 treated, control), daily dexamethasone for 24 days (n=4 treated, control), and 20 hour fasting (n=2 fasted, n=2 fed).
[18F]flurodeoxy-glucose PET was used to image whole-body glucose utilisation. To overcome manual segmentation limitations, an automated multi-organ segmentation method was developed for preclinical MRI using nnU-net, an artificial intelligence architecture[2,3]. The nnU-net was trained on 18 preclinical MRI scans with 21 manual tissue annotations. Evaluation on 8 additional mice revealed high accuracy (Dice Coefficients: 0.72-0.91 for 17 tissues). Adipose tissues had lower accuracy but retained good specificity. Due to low accuracy, pancreas segmentation was excluded. All mice used for training and testing the nnU-net were imaged with the same protocol, sourced from the described datasets, with additional scans from different time points.
After segmenting the scans, we measured mean Standardized Uptake Values (quantitative measure of metabolic activity) for each tissue. Significant differences (p<0.05) were observed following the various interventions (GDF-15, dexamethasone, fasting) compared to control. Network analysis provided insights into potential inter-organ interactions, while Linear Discriminant Analysis successfully distinguished between each metabolic state.
This study presents a novel method for automated segmentation and analysis within preclinical PET/MRI. This method significantly improves efficiency and provides new analysis of total-body metabolic phenotypes. We are currently applying this approach to explore metabolic changes associated with cancer cachexia, aiming to improve our understanding of systemic metabolic dysregulation in both preclinical models and clinical settings.
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