bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of body‐surface area on patients’ outcome in younger adults with acute myeloid leukemia
Authors: Cahu Xavier , Carré Martin , Recher Christian , Pigneux Arnaud , Hunault‐Berger Mathilde , Vey Norbert , Chevallier Patrice , Delaunay Jacques , Gyan Emmanuel , Lioure Bruno , Bonmati Caroline , Himberlin Chantal , Hicheri Yosr , Guillerm Gaelle , Didier Bouscary , Larosa Fabrice , Ojeda‐Uribe Mario , Bernard Marc , Bene Marie C. , Ifrah Norbert , Cahn Jean‐Yves 
Published: January 2017

AbstractObjectivesAnthracyclines and cytarabine are cornerstones for intensive chemotherapy in acute myeloid leukemia (AML). The goals of this study were to comprehensively assess deviations from theoretical doses and the impact of body‐surface area (BSA) on patients’ characteristics, physicians’ strategy, dose adjustment, and clinical outcome.MethodsThe GOELAMS 2001 phase III trial included 823 AML patients below 60 years of age. In the course of treatment, anthropomorphic parameters and chemotherapy doses were prospectively registered.ResultsVery high BSA (≥2.15 m2) was the factor most significantly associated with the physician's decision to reduce chemotherapy doses during induction and postremission therapy. Despite similar AML characteristics and therapeutic strategies, the very high BSA group exhibited a significantly worse survival (5‐years OS of 27%) compared to the low (BSA≤1.5 m2), intermediate (1.5 m2<BSA≤2.0 m2), or high (2 m2<BSA<2.15 m2) BSA groups (46%, 47%, 56%, respectively) (P=.009). In the very high BSA group, dose capping was associated with worse overall survival, although not significantly (P=.09).ConclusionThe presence of a very high BSA is the main reason prompting physicians to reduce chemotherapy doses in adult AML. Furthermore, these patients display a poor outcome and could benefit from full doses calculated on actual BSA.
Multi‐timescale interactions between pink and chum salmon catch per unit effort in the Bering Sea
Authors: Watanabe Kyuji 
Published: January 2017

AbstractBased on generalized linear models, interspecific interactions were identified between chum and pink salmon. In addition, the effects of sea surface temperature and location on the variability of catch per unit effort (CPUE) of chum salmon from gill‐net surveys carried out between 1972 and 2010 were investigated. In the optimal model, interspecific interactions between CPUEs of chum and pink salmon on a year scale were positive for approximately half of all years in the central Bering Sea. In addition, interspecific interactions on a multi‐year scale were positive in even‐numbered years. The effects of location on the CPUE of chum salmon were significant variables in the optimal model. The CPUEs of chum salmon located near the continental shelf in the Bering Sea were higher than those of other locations. This study provides new evidence of positive interspecific interactions between the CPUEs of chum and pink salmon. The results also suggest that the standardized CPUE of chum salmon from the gill‐net surveys reflects relative chum salmon abundance in the North Pacific Ocean in the following year.
Up, up and away: bird‐mediated ectozoochorous dispersal between aquatic environments
Authors: Coughlan Neil E. , Kelly Thomas C. , Davenport John , Jansen Marcel A. K. 
Published: January 2017

Summary

Aquatic birds can facilitate the dispersal of plants, animals, microbes and fungi. Here, we review existing literature on bird‐mediated external (ectozoochorous; synonyms epizoochorous, exozoochorous) dispersal to determine the importance of birds as mobile links between aquatic environments, and to evaluate ectozoochory as a mechanism of dispersal for aquatic organisms and their propagules (collectively referred to as dispersal units). Bird‐mediated ectozoochory occurs when dispersal units stick to feathers, feet and bills, become enmeshed within plumage or encapsulated within mud coating the soft parts of vector birds.

The importance of waterbird‐mediated ectozoochorous dispersal relates to the topical problems of increasing anthropogenic habitat fragmentation, climate change and the associated alterations in species distributions and biological invasions. Nevertheless, some aspects of the bird‐mediated ectozoochorous dispersal remain understudied, and poorly understood.

This review identifies two areas where further research is required. Firstly, the quantitative contribution of bird‐mediated ectozoochory to overall dispersal remains unclear. Secondly, greater consideration of all the requirements necessary for successful waterbird‐mediated ectozoochorous dispersal is needed. In particular, the impact of factors which influence attachment and detachment of dispersal units (e.g. dispersal unit densities, preening behaviour and the role of encapsulating mud) needs further examination. Moreover, few investigators have taken the step of examining viability of found dispersal units, and fewer still have examined tolerances of dispersal units to the ‘in‐flight’ conditions experienced during transport, in order to determine probability of survival of external dispersal.

Evidence presented in this review indicates that bird‐mediated ectozoochorous transport of aquatic dispersal units is a frequent process, at least at a local scale, and therefore needs to be considered in the context of connectivity and gene flow between isolated aquatic environments.
Anticipating changes to future connectivity within a network of marine protected areas
Authors: Coleman Melinda A. , Cetina‐Heredia Paulina , Roughan Moninya , Feng Ming , van Sebille Erik , Kelaher Brendan P. 
Published: January 2017

AbstractContinental boundary currents are projected to be altered under future scenarios of climate change. As these currents often influence dispersal and connectivity among populations of many marine organisms, changes to boundary currents may have dramatic implications for population persistence. Networks of marine protected areas (MPAs) often aim to maintain connectivity, but anticipation of the scale and extent of climatic impacts on connectivity are required to achieve this critical conservation goal in a future of climate change. For two key marine species (kelp and sea urchins), we use oceanographic modelling to predict how continental boundary currents are likely to change connectivity among a network of MPAs spanning over 1000 km of coastline off the coast of eastern Australia. Overall change in predicted connectivity among pairs of MPAs within the network did not change significantly over and above temporal variation within climatic scenarios, highlighting the need for future studies to incorporate temporal variation in dispersal to robustly anticipate likely change. However, the intricacies of connectivity between different pairs of MPAs were noteworthy. For kelp, poleward connectivity among pairs of MPAs tended to increase in the future, whereas equatorward connectivity tended to decrease. In contrast, for sea urchins, connectivity among pairs of MPAs generally decreased in both directions. Self‐seeding within higher‐latitude MPAs tended to increase, and the role of low‐latitude MPAs as a sink for urchins changed significantly in contrasting ways. These projected changes have the potential to alter important genetic parameters with implications for adaptation and ecosystem vulnerability to climate change. Considering such changes, in the context of managing and designing MPA networks, may ensure that conservation goals are achieved into the future.
Are fish outside their usual ranges early indicators of climate‐driven range shifts?
Authors: Fogarty Hannah E. , Burrows Michael T. , Pecl Gretta T. , Robinson Lucy M. , Poloczanska Elvira S. 
Published: January 2017

AbstractShifts in species ranges are a global phenomenon, well known to occur in response to a changing climate. New species arriving in an area may become pest species, modify ecosystem structure, or represent challenges or opportunities for fisheries and recreation. Early detection of range shifts and prompt implementation of any appropriate management strategies is therefore crucial. This study investigates whether ‘first sightings’ of marine species outside their normal ranges could provide an early warning of impending climate‐driven range shifts. We examine the relationships between first sightings and marine regions defined by patterns of local climate velocities (calculated on a 50‐year timescale), while also considering the distribution of observational effort (i.e. number of sampling days recorded with biological observations in global databases). The marine trajectory regions include climate ‘source’ regions (areas lacking connections to warmer areas), ‘corridor’ regions (areas where moving isotherms converge), and ‘sink’ regions (areas where isotherms locally disappear). Additionally, we investigate the latitudinal band in which first sightings were recorded, and species’ thermal affiliations. We found that first sightings are more likely to occur in climate sink and ‘divergent’ regions (areas where many rapid and diverging climate trajectories pass through) indicating a role of temperature in driving changes in marine species distributions. The majority of our fish first sightings appear to be tropical and subtropical species moving towards high latitudes, as would be expected in climate warming. Our results indicate that first sightings are likely related to longer‐term climatic processes, and therefore have potential use to indicate likely climate‐driven range shifts. The development of an approach to detect impending range shifts at an early stage will allow resource managers and researchers to better manage opportunities resulting from range‐shifting species before they potentially colonize.
Restrictive allograft syndrome and idiopathic pleuroparenchymal fibroelastosis: do they really have the same histology?
Authors: Montero Maria A , Osadolor Tina , Khiroya Reena , Salcedo Maria Teresa , Robertus Jan L , Rice Alexandra , Nicholson Andrew G , Roman Antonio , Monforte Victor 
Published: January 2017

AimsRestrictive allograft syndrome (RAS) and idiopathic pleuroparenchymal fibroelastosis (IPPFE) are two different diseases reported to share the same histology. RAS relates to chronic allograft dysfunction in lung transplantation, with IPPFE being a rare condition in native lungs. Our aim is to compare their histologies alongside biopsies of usual interstitial pneumonia (UIP), to determine if there are differences that might help to elucidate the pathogenesis.Methods and resultsWe selected four postmortem allograft lungs from patients who developed a clear clinical RAS pattern, five biopsies diagnosed as IPPFE, five UIP biopsies and five sections of normal lung. Histopathological features were described without knowledge of clinical and radiological features. Both RAS allografts and IPPFE biopsies showed intra‐alveolar fibrosis and elastosis (IAFE), but RAS allografts also showed concomitant obliterative bronchiolitis, vascular lymphoplasmacytic inflammation within fibrointimal thickening, less fibroblastic foci (FF) at the advancing edge of the fibrosis (one against 14.4 FF in 2 mm2) and a slight reduction of the capillary network compared to UIP (P = 0.07) and controls (P = 0.06). The main differences seen in UIP were the lack of IAFE and the presence of honeycomb change.ConclusionsRAS and PPFE histopathology both show IAFE, but display various differences, particularly in their vascular morphology that may allow further understanding of pathogenesis.
Clinicopathological analysis of 12 patients with Epstein–Barr virus‐positive primary intestinal T/natural killer‐cell lymphoma (EBV+ ITNKL)
Authors: Hu Lei‐Ming , Takata Katsuyoshi , Miyata‐Takata Tomoko , Asano Naoko , Takahashi Emiko , Furukawa Katsuya , Miyoshi Hiroaki , Satou Akira , Kohno Kei , Kosugi Hiroshi , Kinoshita Tomohiro , Hirooka Yoshiki , Goto Hidemi , Nakamura Shigeo , Kato Seiichi 
Published: January 2017

AimsEpstein–Barr virus‐positive (EBV+) intestinal T/natural killer (NK) cell lymphoma (ITNKL) is an uncommon tumour with an extremely aggressive clinical behaviour. However, the clinicopathological characteristics of this tumour, including T cell receptor (TCR) phenotype and the patient's background, remain unknown. The aim of this study was to elucidate the detailed clinicopathological profile of EBV+ ITNKL.Methods and resultsWe enrolled 12 patients with EBV+ ITNKL without nasal involvement into the study. All patients were characterized by involvement of the small intestine with concurrent lesions of the large intestine in two patients. Seven patients (58%) had Lugano stages IIE/IV disease and eight (67%) were categorized as high–intermediate/high‐risk according to the Prognostic Index for PTCL (PIT). Three patients (25%) with an age of onset of less than 50 years had chronic active EBV infection (CAEBV). Five CD56‐positive patients (42%) had a poorer prognosis than those without CD56 expression (P = 0.008). NK cell‐type lymphoma defined by the absence of any TCR expression or clonal TCR‐γ rearrangement was found in six patients (50%). Interestingly, EBV+ intra‐epithelial lymphocytosis was observed in one case with a background of CAEBV.ConclusionsThis study is the first to shed light on the significant heterogeneity of EBV+ ITNKL and its relationship with CAEBV, especially in patients younger than 50 years of age. These observations will provide a guide for diagnostic and therapeutic approaches in routine practice.
First record of microsporophyll genus Caytonanthus Thomas from Early Cretaceous beds of South Rewa Gondwana Basin, India: Its evolutionary and palaeogeographical significance
Authors: Prakash Neeru , Das Neelam 
Published: January 2017

AbstractPteridosperms (seed ferns) are an extinct group of large and diverse plants. They were dominant elements during Palaeozoic and were also an important component in the Mesozoic vegetation but declined globally in the Cretaceous time with the radiation of angiosperms. The order Caytoniales of Mesozoic pteridosperm is an extinct group of seed ferns in the vegetation. They thrived for about 100 million years from the Late Triassic to the Late Cretaceous. Although they never attained dominant status, their rare occurrence in the vegetation is quite important and fascinating. For this extinct group of seed fern, Thomas () erected a new order Caytoniales which includes three organ genera Caytonia (megasporophyll), Caytonanthus (microsporophyll) and Sagenopteris (leaves). This paper is aimed to document first record of microsporophyll genus Caytonanthus, obtained from the Lower Cretaceous beds of the South Rewa Gondwana Basin of the Indian Peninsula. Its morpho‐characters, palaeogeographic distribution, along with its plausible southern origin through ancestral group like Glossopteridales, are surmised here.
The Aptian–Cenomanian flora of the Razdolnaya coal Basin (Primorye region, Russia)
Authors: Volynets Elena , Bugdaeva Eugenia 
Published: January 2017

AbstractTaxonomic composition of the Aptian‐Cenomanian flora collected from the Razdolnaya coal Basin, Primorye, is described along with a geological description of sediments containing fossil plants. This is the first report of finding the fossil angiosperms Dicotylophyllum sp. and some indeterminable platanoids in the upper part of the Lipovtsy Formation (Late Lipovtsy floral assemblage), the age of which is determined as the Aptian‐Early Albian. The deposits of the overlying Korkino Group were paleobotanically characterized for the first time.
Sleep quality and its relationship with quality of life in Iranian pregnant women
Authors: Effati‐ Daryani Fatemeh , Mirghafourvand Mojgan , Mohammad‐Alizadeh‐Charandabi Sakineh , Shiri‐Sarand Fatemeh , Zarei Somayeh 
Published: January 2017

AbstractSleep disorders are a common problem during pregnancy and may affect quality of life. This study aimed to determine the status of sleep quality and its relationship with quality of life in Iranian pregnant women. This cross‐sectional study was conducted on 565 women recruited using 2‐stage cluster sampling methods. Data were collected using sociodemographic characteristics; quality of life; and Pittsburgh sleep quality questionnaire between March and May 2015. About 6% of the women had a sleep disorder. There were significant correlations between quality of life and total score of sleep quality, subdomains of habitual sleep efficiency, sleep disturbance, and daytime dysfunction. Paying attention to the sleep quality as an effective factor of quality of life can promote sleep quality and hence quality of life of pregnant women.
The Past is Ever Present: Transnationalism Old and New – Italian and Mexican Immigrants in theUS
Authors: Schmid Carol L. 
Published: January 2017

AbstractThe paper focuses on what is old and what is new in transnationalism by analyzing extraterritorial attempts of the Italian and Mexican governments. During the large southern/ eastern European immigration to theUSfrom 1890 to the 1920s, Italian immigrants reached 24 percent of the immigrant wave. Mexican documented and undocumented immigrants from the 1980s until 2010s made up 30 percent of the immigrant wave almost a century later. Transnational immigrants live in a country in which they do not claim citizenship rights and claim citizenship rights in a country they do not live in. Therefore migration and immigrant policies challenge both sending and receiving states. Foreign governments are limited in the policies and practices that they can enforce. A comparison of state policies from Italy and Mexico challenges the fact that transnationalism is significantly different and new.
Novel magnetoelectric composites of cobalt iron alloy and barium titanate
Authors: Walther Till , Köferstein Roberto , Ebbinghaus Stefan G. 
Published: January 2017

AbstractMagnetoelectric barium titanate ceramics with embedded cobalt iron alloy particles (Co1/3Fe2/3)x–(BaTiO3)(1−x), with x=0.2, 0.4, and 0.6, were prepared by a polyol‐mediated synthesis with subsequent sintering in a reducing forming gas atmosphere. The samples were characterized by XRD and SEM/EDX measurements. The sizes of the Co1/3Fe2/3 grains increase with x. Impedance spectroscopy showed a behavior similar to pure BaTiO3, in particular the occurrence of the ferroelectric‐paraelectric phase transition, and high permittivities for the sample with x=0.6, that is, near the percolation threshold. The samples exhibit soft ferromagnetic properties with large saturation magnetizations of 2.5 μB/atom and narrow hystereses. Detailed magnetoelectric investigations revealed a unique DC‐field dependence of αME for all three compositions. Most remarkably, the sample with x=0.4 possesses a broad ME hysteresis and an inversion of the sign of αME at 5 kOe.
A systematic review of psychometric testing of instruments that measure intention to work with older people
Authors: Che Chong Chin , Hairi Noran Naqiah , Chong Mei Chan 
Published: January 2017

AbstractAimsTo review systematically the psychometric properties of instruments used to measure intention to work with older people.BackgroundNursing students are part of the future healthcare workforce; thus, being aware of their intention to work with older people would give valuable insights to nursing education and practice. Despite a plethora of research on measuring intention to work with older people, a valid and reliable instrument has not been identified.DesignA systematic literature review of evidence and psychometric properties.Data sourcesEight database searches were conducted between 2006 ‐ 2016.Review methodsEnglish articles were selected based on inclusion and exclusion criteria. The COSMIN checklist was used to assess instruments reporting a psychometric evaluation of validity and reliability.ResultsOf 41 studies identified for full text review, 36 met the inclusion criteria. Seven different types of instruments were identified for psychometric evaluation. Measures of reliability were reported in eight papers and validity in five papers. Evidence for each measurement property was limited, with each instrument demonstrating a lack of information on measurement properties. Based on the COSMIN checklist, the overall quality of the psychometric properties was rated as poor to good.ConclusionNo single instrument was found to be optimal for use. Studies of high methodological quality are needed to properly assess the measurement properties of the instruments that are currently available. Until such studies are available, we recommend using existing instruments with caution.
The effects of the empowerment education program in older adults with total hip replacement surgery
Authors: Huang Tzu‐Ting , Sung Chia‐Chun , Wang Woan‐Shyuan , Wang Bi‐Hwa 
Published: January 2017

AbstractAimsTo measure the effectiveness of an education empowerment program on primary (self‐efficacy and self‐care competence) and secondary outcomes (Activities of Daily Life, mobility, depressive mood and quality of life) for older adults with total hip replacement surgery.BackgroundDegenerative arthritis is a common and serious chronic illness that impacts the quality of life of older adults. As joints continue to degenerate and the hip damaged by arthritis, activities of daily life will be difficult to perform due to severe hip pain and joint stiffness. Therefore, hip replacement surgery should be considered and effective nursing care should be provided to improve the recovery of older adults.DesignA prospective randomized control trial.MethodsA trial was conducted from September 2013 ‐ May 2014 in two hospitals in northern Taiwan. 108 participants were random assigned to either the education empowerment group or in the comparison group. The researchers collected baseline data at admission and outcomes on the day of discharge, one month after and three months after the discharge.ResultsAfter the interventions, the education empowerment group participants demonstrated significantly higher self‐care competence and self‐efficacy and lower depressive inclinations compared with those in the comparison group. Participants in both groups significantly improved on activities of daily life, mobility and quality of life over the course of the interventions.ConclusionThis education empowerment intervention was very effective in enhancing participants’ outcomes. Moreover, involving both older adults and their caregivers for the participation this program is recommended for a greater impact.
Avian higher level biogeography: Southern Hemispheric origins or Southern Hemispheric relicts?
Authors: Mayr Gerald 
Published: January 2017

AbstractA recent analysis of a comprehensive phylogenetic data set suggested Southern Hemispheric origins for various higher level taxa of neornithine (crown group) birds. These results contrast with hypotheses derived from the fossil record, with the occurrence of successively branching stem group representatives of many “Southern Hemispheric” bird groups in the early Cenozoic of Europe and North America suggesting relict extant distributions. However, a selective consideration of the fossil record and the merging of extant ranges may have resulted in a skewed picture of the past biogeographical history of birds. For future studies, it is proposed that multiple taxa of successively branching Northern Hemispheric stem group representatives are considered to narrow down the ancestral areas of the crown group representatives.