bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of technologies for the development and use of virgin, fallow lands on agroecological stability and soil fertility
Authors: Chebochakov E. Ya. , Ivanov O. A. , Kapsargin A. I. , Murtaev V. N. 
Published: October 2024

Relevance. The research was carried out in order to analyze the impact of technologies for the development of virgin and fallow lands on erosion processes in the steppe zone in the 60s and modern conditions.Methods. The analysis of approaches to the prevention of soil degradation and desertification of the territory is carried out based on materials obtained in the steppe zone of the Republic of Khakassia in the second half of the XX century and in modern conditions. We used the results of the application of technologies for the development of virgin and fallow lands of Tselinnoye LLC in different periods. Information about dust storms was taken from data from the Bey and Shire weather stations. In 1954–1960 when plowing the chernozem of the southern virgin lands, technology was used using plows, huskers and other tillage tools. The lack of adapted ways of developing and using new lands has led to an outbreak of wind erosion of soils over large areas, including in the south-east of the country.Results. The dump system of soil treatment during the mass development of virgin and fallow lands in the 60s, without taking into account soil, climatic and other conditions, led to a strong development of wind erosion. The number of days with dust storms in Khakassia reached up to 4.8–11.6 per year. In modern conditions, the removal of highly ventilated soils from arable lands and the use of strip placement of crops and minimal tillage on the rest of the arable land contribute to increasing the erosion resistance of agricultural landscapes. The use of the Tornado 500 herbicide in August during the development of the deposit reduces the erodibility by 2.5 times, compared with the technology with its introduction in early summer.
Síndrome de encefalopatía posterior reversible (PRES) y anemia hemolítica: dos complicaciones graves e inhabituales de glomerulonefritis aguda post estreptocócica
Authors: Tomarelli R. Gianfranco , Arriagada S. Daniela , Donoso F. Alejandro 
Published: October 2024

La causa más frecuente de síndrome nefrítico en la población pediátrica es la glomerulonefritis aguda post-estreptocócica (GNAPE). Una complicación infrecuente es el síndrome de encefalopatía posterior reversible (posterior reversible encephalopathy syndrome, PRES), caracterizado por edema cerebral vasogénico subcortical y sintomatología neurológica variable. El desarrollo de anemia hemolítica autoinmune, es una presentación clínica atípica. Objetivo: Reportar la coexistencia de dos complicaciones extrarrenales inhabituales y graves de la GNAPE y discutir potenciales mecanismos involucrados en el desarrollo de estas.Caso Clínico: Paciente masculino de 4 años, con historia de 5 días de hematuria y edema, agregándose cefalea, náuseas y vómitos, ingresó en estatus convulsivo y crisis hipertensiva. Laboratorio mostró hipocomplementemia C3 y títulos elevados de Antiestreptolisina O, lo que se interpretó como GNAPE. Evolucionó con encefalopatía por lo que se sospechó PRES secundario a emergencia hipertensiva, lo que finalmente se confirmó mediante resonancia magnética de cerebro. Cursó además con anemia hemolítica autoinmune, con hemoglobina hasta 5 g/dL. Su tratamiento se basó en terapia antihipertensiva, medidas de neuro protección y tratamiento esteroidal. Egresó a los 31 días de hospitalización, asintomático a los 6 meses post alta. Conclusiones: Se debe tener un alto índice de sospecha de PRES ante la aparición de sintomatología neurológica inespecífica en el curso de la evolución de una GNAPE. La anemia existente en ocasiones puede ser de carácter autoinmune.
Ingesta de micronutrientes en pacientes con epilepsia refractaria tratados con dieta cetogénica
Authors: Velandia Silvia , Astudillo Patricio , Acevedo Keryma , Le Roy Catalina 
Published: October 2024

La Dieta Cetogénica (DC) es una estrategia no farmacológica para el manejo de Epilepsia Fármaco-resistente (EFR) y algunos errores congénitos del metabolismo como el déficit del transportador de glucosa Glut1. Se caracteriza por ser restrictiva, afectando el aporte de micronutrientes. Existen diferentes modalidades variando la ingesta alimentaria y deficiencias nutricionales. Objetivo: Determinar el aporte de micronutrientes en distintas modalidades de DC. Pacientes y Método: Estudio observacional, transversal en pacientes con EFR y déficit del transportador de glucosa Glut1. Se evaluó la ingesta alimentaria de 21 micronutrientes, con análisis según modalidad de DC (Clásica o Modificada de Atkins (DMA)), uso de fórmula especial y adecuación de consumo de la ingesta diaria recomendada (IDR) según edad y sexo, definiendo <75% como deficiente. Resultados: Se evaluaron 19 pacientes, mediana de edad 62 meses (RIC: 20.5-79), 12/19 (63,2%) sexo masculino, 13/19 (68,4%) eutróficos, 5/19 (26,3%) usuarios de gastrostomía, modalidad DMA 10 (52,6%), uso de fórmula especial 7/19 (36,8%). Se encontraron micronutrientes deficientes 16/21 (76,2%) en dieta clásica y 9/16 (42,9%) en DMA. El aporte de vitamina D, B2, B12, sodio, fósforo, zinc y selenio fue significativamente más bajo en dieta clásica que DMA, las medianas de adecuación de consumo de vitaminas A, C, D, E y K fueron >100%. El uso de fórmula especial completó los requerimientos en DMA. Conclusiones: El aporte de micronutrientes en las diferentes modalidades de la DC es reducido para la mayoría de ellos, siendo la DMA con fórmula aquella con un aporte más adecuado en micronutrientes. Estos resultados deben considerarse en el seguimiento nutricional y planificación de suplementación.
Identification of Potential Drug Interactions in Osteoarthritis Patients at X Hospital, South Tangerang, 2019
Authors: Hasan Delina , Yardi Yardi , Musdja M.Yanis , Suryani Nelly , Samad Abdul 
Published: October 2024

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive damage to joint cartilage and diarthrodial joint structures. In Indonesia, OA is the most common rheumatic disease. The causes of OA are multifactorial, such as obesity and genetic and racial factors, the risk of which rises at the age of 50 years. This study aimed to assess the therapeutic use of OA and drug interactions that occur in patients with osteoarthritis. This study used a cross-sectional design with prospective data collection through medical records of 60 OA patients in 2019 who met the inclusion and exclusion criteria. The Results showed that 87 drug interactions occurred in OA patients in this study; the other results were found to be a relationship between comorbidities and significant drug interactions (P value <0.05). The drug most widely interacted is ketorolac (45.71%), the interaction between paracetamol with ranitidine (15.71%), the interaction of ketorolac with ranitidine (12.86%), and ketorolac with metformin (11.43%). The most common mechanism of interaction is in pharmacodynamic (66.67%), and the pharmacokinetic interaction mechanism is 25.29%. The highest severity of interactions was found to be major (58.62%), and moderate severity was 25.3%. In conclusion, it was found that 87 drug interactions occurred in OA patients in this study. Other results were found to be a relationship between comorbidities and significant drug interactions. The drug most widely interacted with is Ketorolac, the interaction between par. The most interaction mechanism is pharmacodynamically. The most severe of interactions were found to be at the major severity level of paracetamol with ranitidine, the interaction of ketorolac with ranitidine, and ketorolac with metformin.
Effect of Feeding Mango and Senna occidentalis Leaf Meals as Replacement to Prophylactic Antibiotic Use on Performance of Broiler Chickens
Authors: Usman Hussaina B. , Sabo Mustapha N. , Sadisu A. B. , Mbakwe Chinedum C. , Jibia Zainab Saminu , Sulaiman Aliyu 
Published: October 2024

A total of 180-day-old broiler chicks were used to evaluate the effect of feeding mango and Senna leaf meal as a replacement to prophylactic antibiotics use on the performance of broiler chickens. The birds were fed mango (MLM) and senna leaf meal (SLM) at 0g, 5gMLM, 7.5gMLM, 5gSLM and 7.5gSLM as treatments in a completely randomized design. Data on phytochemicals, growth performance, carcass characteristics, and haematological and serum biochemical parameters were collected. Data collected were subjected to variance analysis. The results show that flavonoids, alkaloids, saponins, tannin and phenol were present in Mango and Senna leaf meals. Total feed costs in diets containing the different levels of MLM and SLM were lower (P<0.05) compared to the control. The feed cost per kg gain was also higher (P<0.05) in the control group compared to 5gMLM. Mortality was higher in the control compared to those fed the different leaf meals. The breast weight of the 5gMLM was higher (P<0.05) than that of 7.5gMLM and 5gSLM. The PCV of the group fed with 5gSLM was lower (p<0.05) compared to the control group and those fed with 5gMLM, 7.5gMLM, and 7.5gSLM. The WBC was higher (p<0.05) in the control group and 5gSLM compared to those fed with 5gMLM and 7.5gSLM. From the results, it can be concluded that 5gM resulted in better growth performance without adverse effects on haematological and serum biochemical parameters. Hence, it is recommended that 5gMLM can be used in the diets of broiler chickens in place of prophylactic antibiotics.
Hubungan Antara Indeks Massa Tubuh (Obesitas) Dengan Kejadian Acne Vulgaris Pada Mahasiswa Angkatan 2020, 2021, Dan 2022 Prodi Pendidikan Dokter Universitas Malahayati Bandar Lampung
Authors: Nurhasanah Tamara , Silvia Eka , Jhonet Aswan , Hamzah M. Syafei , Muliasih Mulat 
Published: October 2024

Acne Vulgaris adalah kondisi kulit yang menyebabkan inflamasi yang berlangsung lama (Wang et al.,2022). Indeks Massa Tubuh (IMT) obesitas berkorelasi dengan peningkatan jumlah lemak tubuh, obesitas juga dapat menyebabkan peningkatan produksi sebum. . Sebum adalah produk kelenjar sebasea yang melembabkan dan melindungi kulit, tetapi produksi berlebihan menyebabkan Acne Vulgaris (Dewinda et al., 2020). Tujuan Penelitian : Mengetahui korelasi antara obesitas dengan acne vulgaris pada mahasiswa prodi pendidikan dokter universitas malahayati bandar lampung. Metode Analitik observasional dengan pendekatan cross sectional. Hasil Penelitian : Dari 235 sampel penelitian didapatkan 195 orang (83,0%)IMT normal dan 40 Orang (17,0%) IMT obesitas. Dari hasil univariat didapatkan Laki-laki berjumlah 78 orang (33,2%) dan perempuan berjumlah 157 (66,8%). Berdasarkan karakteristik mahasiswa dengan prevalensi kejadian Acne vulgaris didapatkan hasil yang menderita pada angkatan 2020 terdapat 18 orang (40,0%), angkatan 2022 terdapat 40 orang (47,6%), dan angkatan 2022 terdapat 49 orang (46,2%). Berdasarkan hubungan status IMT dengan kejadian acne vulgaris didapatkan 82 orang IMT normal (42,1%) yang menderita dan 113 orang IMT normal (57,9%) tidak menderita serta terdapat 25 orang IMT obesitas (62,5%) yang menderita dan 15 orang IMT obesitas (37,5%) tidak menderita acne vulgaris. Kesimpulan : Terdapat hubungan antara IMT (obesitas) dengan kejadian acne vulgaris pada mahasiswa angkatan 2020,2021, dan 2022 prodi pendidikan dokter universitas malahayati bandar lampung ( P= 0,018)
Pengaruh Kebiasaan Cuci Tangan Selama Masa Pandemi Covid-19 Terhadap Kejadian Dermatitis Tangan Pada Mahasiswa Fakultas Kedokteran Universitas Hang Tuah
Authors: Willy Johannes , Ardiana Dian , Noer Shoffi Muhammad , Diarsvitri Wienta 
Published: October 2024

Pandemi Covid-19 menyebabkan munculnya beberapa kebiasaan baru, diantaranya kebiasaan cuci tangan. Peningkatan frekuensi cuci tangan menyebabkan peningkatan kejadian dermatitis tangan. Tujuan penelitian untuk mengetahui pengaruh frekuensi cuci tangan dan jenis antiseptik terhadap kejadian dermatitis tangan pada mahasiswa. Jenis penelitian adalah analitik observasional. Data didapatkan melalui kuesioner online. Responden dalam penelitian ini adalah mahasiswa semester 7 Fakultas Kedokteran Universitas Hang Tuah tahun 2022, yang bersedia dan tidak memiliki riwayat penyakit asma, hay fever, serta dermatitis atopik pada masa kanak-kanak. Data diolah dengan uji statistik Chi-Square. Hasil penelitian menunjukkan 51,5% responden memiliki frekuensi cuci tangan lebih dari lima kali sehari dan 86,4% responden melakukan cuci tangan dengan air dan sabun. Uji Chi-Square menunjukkan nilai p = 0,964 dan p = 0,727 yang berarti tidak terdapat pengaruh frekuensi cuci tangan maupun jenis antiseptik terhadap kejadian dermatitis tangan pada mahasiswa.
Dampak Ketidakpatuhan Pasien Hipertensi Terhadap Terjadinya Coronary Artery Disease : Laporan Kasus
Authors: Jessica Jessica , Anna Anastasia , Priambodo Ayu Prawesti 
Published: October 2024

Faktor risiko Penyakit Jantung Koroner paling umum adalah hipertensi. Hipertensi jarang diketahui gejala awalnya, sehingga hipertensi sering disebut silent disease. Pengobatan yang diberikan pada gejala awal hipertensi akan menurunkan terjadinya komplikasi. Mengidentifikasi tanda gejala hipertensi dan dampak ketidakpatuhan pasien hipertensi terhadap kejadian Coronary Artery Disease menjadi tujuan dari penelitian ini. Penelitian ini menggunakan desain case report dengan melakukan pengumpulan data berupa wawancara kepada klien. Laki-laki berusia 54 tahun memiliki riwayat kolesterol tinggi dan hipertensi sejak tahun 2021, tetapi klien mengabaikan dan tetap menjalani gaya hidup yang tidak sehat. Dua tahun kemudian klien mengalami serangan jantung. Hasil fungsi jantung tidak baik yaitu hanya 40%. Setelahnya, klien rutin kontrol ke Poli Jantung untuk persiapan coronary artery bypass grafting , tetapi gaya hidup klien masih tidak berubah. Januari 2024 klien datang ke Instalagi Gawat Darurat dengan keluhan nyeri hilang timbul di dada kiri dengan skala 4/10. Kemudian klien dirawat inap untuk operasi coronary artery bypass grafting. Tanda gejala hipertensi yang paling umum adalah sakit kepala. Ketidakpatuhan dalam pengobatan dan kontrol rutin hipertensi meningkatkan resiko kematian kardiovaskuler. Deteksi dini tanda gejala hipertensi menjadi penentu dalam pengobatan hipertensi. Hipertensi yang diobati pada gejala awal dan patuh pada pengobatan menurunkan resiko komplikasi kardiovaskuler.
Game “Three Disabled People’s Journey” Through Information Services at Junior High School 6 Palangka Raya
Authors: Pangestie Esty Pan , Suriatie Mimi , Sangalang Oktamia Karuniaty , Sukarningsi Susi 
Published: October 2024

Background: Teachers are important in the activities and efficiency of information services in schools. Teachers can also act as mentors for their students. To help the education process and the quality of human resources, one of the government's policies is to raise guidance and counseling in schools by the Minister's Decree on January 15, 1975 No. 008d / 1975 and 008e / 1975, the following is emphasized again by Decree No. 84/1993 and No. 118/1996, and finally contained in the Merdeka curriculum is interest and talent. Aim: The purpose of this study is" to know the participation of teachers in implementing the use of the game "trip of three disabled people" through information services at Junior High School 6 Palangka Raya ", the sample amounted to 57 teachers at the school. Method: This research uses a quantitative descriptive method to make planning in a systematic, factual, and accurate manner Regarding the facts, and characteristics of the population so that the results of this research will draw conclusions that only apply specifically to the research object, namely the teachers of Junior High School 6 Palangka Raya.The main data collection tool uses the Check List technique, namely: a way to obtain data by making a list of questions addressed to all teachers at Junior High School 6 Palangka Raya. Result and Discussion: The results of the study showed that almost all components of the objectives in the study were implemented with a fairly high percentage of 100% by teachers in schools. This means that teachers are very involved and support information services at Junior High School 6 Palangka Raya.
Consistency in verbal expression of death row criminals: concluding life with emotions
Authors: Mehra Vaibhav , Shukla Unmesh , Aggarwal Nitisha , Pundir Amit , Saxena Geetika Jain , Singh Sanjeev 
Published: October 2024

IntroductionThere is a lack of both data and, more significantly, computational analyses of the linguistic behavior near an individual's final moments of life. The present study is aimed to reduce human bias and save time in psycholinguistic studies by providing data-backed insights.MethodsA novel machine learning based pipeline proposed, using elements of semantic similarity (BERT and transformers) and emotion extraction in collaboration, to analyze the final statements of death row inmates to understand the consistency in their verbal expression moments before their death. A new method of analysis was proposed in this study to explore the notions inherent in the statements. A large database of 466 final statements from death row inmates in Texas was utilized in this study. Manual notion analysis was validated by a computational method of notion inferencing.ResultsBasic emotions of Anger and Fear majorly dominated the statements, constituting 54% of the whole, while 21% of all statements were of emotional states of Happiness and Serenity.DiscussionThe outcomes of this study are expected to contribute to psychological analyses of humans, moments before death, and provide insights to criminology researchers to formulate better strategies of rehabilitation and debate the death penalty.
Metal-antimicrobial peptides combo: promising weapons to combat bacteria invaders
Authors: Falcigno Lucia , Braccia Simone , Bellavita Rosa , D’Auria Gabriella , Falanga Annarita , Galdiero Stefania 
Published: October 2024

Antimicrobial resistance has significantly increased over the last 30 years, prompting scientists to continuously look for novel, effective ways to combat drug-resistant bacteria and fungi. Due to their broad range of effectiveness, ease of synthesis, and ability to avoid resistance, antimicrobial peptides (AMPs) represent a potential approach. The direct investigation of metal effects on peptide activity has not received much attention. Divalent metal ions such as Zn(II), Cu(II), Ni(II), and Fe(II) do, in fact, influence some AMPs, producing an effect on their mode of action or function. Although the precise process by which metals are involved in microbial death is not well understood, this review goes into detail on several potential strategies to enhance AMPs activity through the synergy with metals. Important variables in these interactions include the individual peptide sequence, the type of metal ion, the capacity of metal to form chelates, and the softness of the ligand/metal complex. This article offers a thorough summary of the ways in which metal ions alter the structure of AMPs to boost their activity or sequester metal to impact on bacteria function.
Impacts of a marine engineering project on hydrodynamics and diffusion characteristics of fluvial pollutants in Laizhou Bay, China
Authors: Wang Zhanjin , Bao Rui , Wang Weizhong , Li Wanhua , Leng Xing , Liang Jinhui , Zhang Wei 
Published: October 2024

IntroductionThe rapid advances in marine engineering projects are exacerbating environmental pressures on bay ecosystems. This study utilized the MIKE 21 model to evaluate the impacts of such projects in Laizhou Bay (LZB) on hydrodynamic conditions and the spread of dissolved inorganic nitrogen (DIN) from riverine inputs.ResultsThe results indicated an expansion of 80.77 km2 in areas with DIN concentrations surpassing 0.5 mg/L 2 months after input from the Yellow River, with increased levels in the southern Yellow River Delta. Decreased flow velocities adjacent to the wave barriers at the Xiaoqing River estuary impeded lateral DIN dispersion, resulting in a 0.93 mg/L increase in DIN concentrations at the river mouth. After the construction of marine engineering projects (2020), significant alterations in the coastline of LZB have markedly modified hydrodynamic characteristics near marine structures, altering DIN dispersion patterns.ConclusionThis study provides crucial information for the management of pollutants at estuaries, understanding dispersion mechanisms, and evaluating the feasibility and environmental compatibility of marine engineering projects.
An adolescent girl with syndrome of inappropriate antidiuretic hormone secretion preceding the diagnosis of olfactory neuroblastoma – a case report
Authors: Sasidharan Pillai Sabitha , Boxerman Jerrold L. , Groblewski Jan C. , DeNardo Bradley D. , Faizan Mohammed K. , Topor Lisa Swartz , Robilliard Renee , Serrano-Gonzalez Monica 
Published: October 2024

ObjectivesWe present an adolescent in whom olfactory neuroblastoma (ONB) was detected on follow-up magnetic resonance imaging (MRI) 2.5 years after SIADH diagnosis. Our case contrasts prior pediatric reports in which ONB and SIADH were diagnosed concurrently.Case presentationA previously healthy 13-year-old girl was found to have SIADH during evaluation for restrictive eating. Work-up ruled out adrenal, thyroid and paraneoplastic causes, diuretic use, and vasopressin receptor and aquaporin channel mutations. Brain MRI was normal except for paranasal sinus (PNS) inflammatory changes to the left fronto-maxillary sinuses and frontoethmoidal recess. The sodium levels normalized with fluid restriction (800-900 ml/m2/day). Multiple repeated attempts to liberalize fluid intake resulted in recurrent hyponatremia. Follow-up brain MRIs 4 and 11 months after the initial presentation showed persistent PNS inflammatory changes. A subsequent brain MRI 31 months after initial presentation demonstrated a lesion in the left frontoethmoidal recess extending into the left nasal cavity and biopsy showed low grade ONB. The patient underwent surgery with normalization of serum sodium on liberalized fluid intake. Seven days after surgery, she had recurrence of SIADH, and brain MRI showed remnant of the ONB at the fovea ethmoidalis. She completed adjuvant radiotherapy though her SIADH persisted.ConclusionsOur case highlights the importance of considering ONB in the evaluation of children with SIADH. Idiopathic SIADH is rare in children and if no cause is identified, computed tomography of sinuses and nasal endoscopy should be considered earlier in the work-up of these patients, particularly in the absence of sinus symptoms.
Experimental study on dynamic response performance of hydrogen sensor in confined space under ceiling
Authors: He Qize , Kong Fanyue , Sun Rong , Li Ruilin , Yang Juntao , Min Qizhong 
Published: October 2024

With the advancement of Fuel Cell Vehicles (FCVs), detecting hydrogen leaks is critically important in facilities such as hydrogen refilling stations. Despite its significance, the dynamic response performance of hydrogen sensors in confined spaces, particularly under ceilings, has not been comprehensively assessed. This study utilizes a catalytic combustion hydrogen sensor to monitor hydrogen leaks in a confined area. It examines the effects of leak size and placement height on the distribution of hydrogen concentrations beneath the ceiling. Results indicate that hydrogen concentration rapidly decreases within a 0.5–1.0 m range below the ceiling and declines more gradually from 1.0 to 2.0 m. The study further explores the attenuation pattern of hydrogen concentration radially from the hydrogen jet under the ceiling. By normalizing the radius and concentration, it was determined that the distribution conforms to a Gaussian model, akin to that observed in open space jet flows. Utilizing this Gaussian assumption, the model is refined by incorporating an impact reflux term, thereby enhancing the accuracy of the predictive formula.