bluuebunny/crossref_metadata_2025_split huggingface dataset:
La responsabilidad civil y los seguros en la construcción de inmuebles: una aproximación comparativa entre el derecho colombiano y francés
Authors: Tamayo Jaramillo Javier , Ossa Gómez Daniel 
Published: December 2016

<p>El colapso del edificio Space en Medellín puso de presente las limitaciones existentes en el ordenamiento jurídico colombiano para lograr una pronta y eficiente indemnización de las víctimas de la indebida construcción en el país. Tras dos años de ocurrido el evento, el presente artículo pretende analizar, desde una perspectiva comparada entre el derecho colombiano y francés, las normas existentes frente a la responsabilidad civil de los constructores y su aseguramiento, con la finalidad de aportar al debate sobre el rumbo que debería tomar al respecto, el ordenamiento jurídico patrio.</p>
Análisis Técnico-Jurídico de la modalidad de cobertura por reclamación o “Claims Made” en los seguros de responsabilidad civil a la luz del ordenamiento jurídico colombiano
Authors: Uribe Lozada Nicolas 
Published: December 2016

<p>El presente escrito pretende realizar un análisis, tanto técnico como jurídico, fundado en la experiencia del mercado de seguros colombiano, las posiciones sentadas por la doctrina y la jurisprudencia y, particularmente el texto de los clausulados actualmente dispuestos por las compañías de seguros, de la operatividad del sistema de cobertura por reclamación hecha o<em> “claims made”, </em>identificando<em> </em>sus falencias, sus bondades y sus elementos fundamentales, sin caer en la tentación de entrar en apasionamientos o posiciones radicales, que busquen defenderlo o atacarlo<em>.</em></p><p>Además de revisar la configuración del siniestro y el cómputo del término de prescripción, se hace un sucinto repaso de sus antecedentes históricos de este sistema y, sus diferentes tipologías, haciendo igualmente, mención a algunos puntos polémicos como, la desprotección del asegurado, y la declaración del estado del riesgo, particularmente en tratándose de seguros colectivos o de grupo.</p><p> </p>
Draft Anaplasma phagocytophilum Genome Sequences from Five Cows, Two Horses, and One Roe Deer Collected in Europe
Authors: Dugat Thibaud , Rossignol Marie-Noëlle , Rué Olivier , Loux Valentin , Marthey Sylvain , Moroldo Marco , Silaghi Cornelia , Höper Dirk , Fröhlich Julia , Pfeffer Martin , Zweygarth Erich , Lagrée Anne-Claire , Boulouis Henri-Jean , Haddad Nadia 
Published: December 2016

ABSTRACT

Anaplasma phagocytophilum
is a zoonotic tick-borne intracellular bacterium responsible for granulocytic anaplasmosis. As it is difficult to isolate and cultivate, only 20
A. phagocytophilum
genomes have been sequenced to date. Here, we present eight
A. phagocytophilum
genome sequences obtained using alternative approaches based on sequence capture technology.
Draft Genome Sequences of Three Clinical Isolates of Tannerella forsythia Isolated from Subgingival Plaque from Periodontitis Patients in the United States
Authors: Stafford Graham P. , Chaudhuri Roy R. , Haraszthy Violet , Friedrich Valentin , Schäffer Christina , Ruscitto Angela , Honma Kiyonobu , Sharma Ashu 
Published: December 2016

ABSTRACT

We report the genome sequences of three clinical isolates of
Tannerella forsythia
from the subgingival plaque of periodontitis patients attending clinics at the School of Dental Medicine, University at Buffalo. The availability of these genome sequences will aid the understanding of the pathogenesis of periodontitis.
Genome Sequence of the Fish Pathogen Yersinia ruckeri Strain 150, Isolated from Diseased Rainbow Trout
Authors: Cascales Desirée , Guijarro José A. , Reimundo Pilar , García-Torrico Ana I. , Méndez Jessica 
Published: December 2016

ABSTRACT

We present here the draft genome of a pathogenic
Yersinia ruckeri
strain, isolated from rainbow trout (
Oncorhynchus mykiss
) affected by enteric redmouth disease. The chromosome has 3,826,775 bp, a GC content of 46.88%, and is predicted to contain 3,538 coding sequences. The data will be useful for comparative pathogenicity studies.
First Complete Genome Sequence of a Simian Foamy Virus Isolate from a Cynomolgus Macaque
Authors: Sakai Koji , Ami Yasushi , Suzaki Yuriko , Matano Tetsuro 
Published: December 2016

ABSTRACT

We report here the first complete proviral genome sequence (DDBJ/ENA/GenBank accession no. LC094267) of a simian foamy virus, SFVmfa/Cy5061, isolated from a cynomolgus macaque (
Macaca fascicularis
). This proviral genome consists of 12,965 nucleotides and has five open reading frames,
gag
,
pol
,
env
,
tas
, and
bet
, as with other foamy viruses.
Genome Sequence of the Acetogenic Bacterium
Butyribacterium methylotrophicum
DSM 3468
T
Authors: Bengelsdorf Frank R. , Poehlein Anja , Schiel-Bengelsdorf Bettina , Daniel Rolf , Dürre Peter 
Published: December 2016

ABSTRACT

Butyribacterium methylotrophicum
DSM 3468
T
is an acetogenic methylotrophic, anaerobic, carbon monoxide–oxidizing bacterium that produces acetate, butyrate, and butanol. The genome consists of a single chromosome (4.3 Mb) and harbors 3,989 predicted protein-encoding genes.
Porphycene dimer-based non-fullerene acceptor for organic solar cell
Authors: Okabe Takuya , Kuzuhara Daiki , Suzuki Mitsuharu , Aratani Naoki , Yamada Hiroko 
Published: December 2016

Porphycene dimers connected by [Formula: see text]-phenylene (DPc– m P) and 2,5-thienylene (DPc–T) linkages have been synthesized from 2,7,12,17-tetrahexyl-3-iodoporphycene by palladium-catalyzed cross-couplings. The crystal structures of porphycene dimers revealed that meta-phenylene linkage provides a highly twisted structure with the dihedral angel of 103° between two porphycene units, while thienylene linkage provides a nearly planar structure of two porphycene units. These porphycene dimers showed strong absorption thorough the visible to NIR regions and HOMO and LUMO energy levels of them are suitable as [Formula: see text]-type materials of organic solar cells (OSCs) in combination with P3HT as a [Formula: see text]-type material. The hole and electron mobilities of the blended films of the porphycene dimers and P3HT obtained by space-charge-limited-current (SCLC) method were 3.7 × 10[Formula: see text] and 0.26 × 10[Formula: see text] cm2.V[Formula: see text].s[Formula: see text] for DPc– m P :P3HT, and 3.2 × 10[Formula: see text] and 0.027 × 10[Formula: see text] cm2.V[Formula: see text].s[Formula: see text] for DPc–T :P3HT. Atomic force microscopy (AFM) and thin-film X-ray diffraction analysis (XRD) measurements indicated that the blended films of the porphycene dimers and P3HT formed amorphous films with smooth and low-roughness surfaces, whereas the blended film of porphycene monomer and P3HT created the highly crystalline film with huge domain structures. The OSCs composed of porphycene dimers and P3HT showed power conversion efficiencies of 0.08% was twice as high as that of monomer-based OSC.
Stomach Cancer Disparity among Korean Americans by Tumor Characteristics: Comparison with Non-Hispanic Whites, Japanese Americans, South Koreans, and Japanese
Authors: Lee Eunjung , Liu Lihua , Zhang Juanjuan , Stern Mariana C. , Barzi Afsaneh , Hwang Amie , Kim Andre E. , Hamilton Ann S. , Wu Anna H. , Deapen Dennis 
Published: December 2016

Abstract
Background: Stomach cancer incidence shows substantial racial-ethnic disparity in the United States, with Korean Americans experiencing by far the highest incidence. We examined stomach cancer incidence trends in Korean Americans by tumor subsite, histology, and stage and compared them with incidence rates in racial-ethnic groups with the second highest rate (Japanese Americans) and the lowest rate (non-Hispanic whites; NHWs) as well as populations in South Korea and Japan.
Methods: We calculated age-adjusted incidence rates by racial-ethnic groups, sex, and tumor characteristics, using the 1988–2012 California Cancer Registry data. Data on South Korea and Japan were obtained from the literature and other resources.
Results: Between 1988 and 2012 in California, Korean Americans had about five times greater incidence than NHWs and twice that of Japanese Americans. Tumor characteristics differed by ethnic group and gender. The incidence in Korean Americans has declined during recent years, for both cardia and noncardia sites and for both intestinal- and diffuse-type histology. Although Korean Americans were diagnosed at an earlier stage than other Californians, the proportion with localized disease (43%) was much smaller than in South Korea (57%), where population-based screening is available.
Conclusions: Stomach cancer incidence declined in the highest risk ethnic groups. However, the persistent disparity between Korean Americans and other racial-ethnic groups warrants additional strategies for prevention and earlier diagnosis.
Impact: Analysis of California Cancer Registry data identified a racial-ethnic subgroup with stomach cancer disparity that may benefit from targeted prevention and screening efforts. Cancer Epidemiol Biomarkers Prev; 26(4); 587–96. ©2016 AACR.
Resting Heart Rate Trajectory Pattern Predicts Arterial Stiffness in a Community-Based Chinese Cohort
Authors: Chen Shuohua , Li Weijuan , Jin Cheng , Vaidya Anand , Gao Jingli , Yang Hui , Wu Shouling , Gao Xiang 
Published: December 2016

Objective—
To examine whether the long-term resting heart rate (RHR) pattern can predict the risk of having arterial stiffness in a large ongoing cohort.

Approach and Results—

This community-based cohort included 12 554 participants in the Kailun study, who were free of myocardial infarction, stroke, arrhythmia, and cancer. We used latent mixture modeling to identify RHR trajectories in 2006, 2008, and 2010. We used multivariate linear regression model to examine the association between RHR trajectory patterns and the risk of having arterial stiffness, which was assessed by brachial–ankle pulse wave velocity in 2010 to 2016. We adjusted for possible confounding factors, including socioeconomic status, lifestyle factors, use of medications, comorbidities, and serum concentrations of lipids, glucose, and high-sensitivity C-reactive proteins. We identified 5 distinct RHR trajectory patterns based on their 2006 status and on the pattern of change during 2006 to 2010 (low–stable, moderate–stable, moderate–increasing, elevated–decreasing, and elevated–stable). We found that individuals with elevated–stable RHR trajectory pattern had the highest brachial–ankle pulse wave velocity value and individuals with the low–stable RHR trajectory pattern had the lowest value (adjusted mean difference=157 cm/s;
P
<0.001). Adjusted odds ratio for risk of having arterial stiffness (brachial–ankle pulse wave velocity ≥1400 cm/s) was 4.14 (95% confidence interval, 2.61–6.57) relative to these 2 extreme categories. Consistently, a higher average RHR, a higher annual RHR increase rate, and a higher RHR variability were all associated with a higher risk of having arterial stiffness.

Conclusions—
Long-term RHR pattern is a strong predictor of having arterial stiffness.
The Paraoxonase Gene Cluster Protects Against Abdominal Aortic Aneurysm Formation
Authors: Yan Yun-Fei , Pei Jian-Fei , Zhang Yang , Zhang Ran , Wang Fang , Gao Peng , Zhang Zhu-Qin , Wang Ting-Ting , She Zhi-Gang , Chen Hou-Zao , Liu De-Pei 
Published: December 2016

Objective—
Abdominal aortic aneurysm (AAA) is a life-threatening vascular pathology, the pathogenesis of which is closely related to oxidative stress. However, an effective pharmaceutical treatment is lacking because the exact cause of AAA remains unknown. Here, we aimed at delineating the role of the paraoxonases (PONs) gene cluster (PC), which prevents atherosclerosis through the detoxification of oxidized substrates, in AAA formation.

Approach and Results—

PC transgenic (Tg) mice were crossed to an
Apoe
−/−
background, and an angiotensin II–induced AAA mouse model was used to analyze the effect of the PC on AAA formation. Four weeks after angiotensin II infusion, PC-Tg
Apoe
−/−
mice had a lower AAA incidence, smaller maximal abdominal aortic external diameter, and less medial elastin degradation than
Apoe
−/−
mice. Importantly, PC-Tg
Apoe
−/−
mice exhibited lower aortic reactive oxidative species production and oxidative stress than did the
Apoe
−/−
control mice. As a consequence, the PC transgene alleviated angiotensin II–induced arterial inflammation and suppressed arterial extracellular matrix degradation. Specifically, on angiotensin II stimulation, PC-Tg vascular smooth muscle cells exhibited lower levels of reactive oxidative species production and a decrease in the activities and expression levels of matrix metalloproteinase-2 and matrix metalloproteinase-9. Moreover, PC-Tg serum also enhanced vascular smooth muscle cell oxidative stress resistance and further decreased the expression levels of matrix metalloproteinase-2 and matrix metalloproteinase-9, indicating that circulatory and vascular smooth muscle cell PC members suppress oxidative stress in a synergistic manner.

Conclusions—
Our findings reveal, for the first time, a protective role of the PC in AAA formation and suggest PONs as promising targets for AAA prevention.
Anticoagulation Use and Clinical Outcomes After Major Bleeding on Dabigatran or Warfarin in Atrial Fibrillation
Authors: Hernandez Inmaculada , Zhang Yuting , Brooks Maria M. , Chin Paul K.L. , Saba Samir 
Published: December 2016

Background and Purpose—
Little is known about the clinical outcomes associated with posthemorrhage anticoagulation resumption for atrial fibrillation. This study had 2 objectives: first, to evaluate anticoagulation use after a first major bleed on warfarin or dabigatran and, second, to compare effectiveness and safety outcomes between patients discontinuing anticoagulation after a major bleed and patients restarting warfarin or dabigatran.

Methods—
Using 2010 to 2012 Medicare Part D data, we identified atrial fibrillation patients who experienced a major bleeding event while using warfarin (n=1135) or dabigatran (n=404) and categorized them by their posthemorrhage use of anticoagulation. We followed them until an ischemic stroke, recurrent hemorrhage, or death through December 31, 2012. We constructed logistic regression models to evaluate factors affecting anticoagulation resumption and Cox proportional hazard models to compare the combined risk of ischemic stroke and all-cause mortality and the risk of recurrent bleeding between treatment groups.

Results—
Resumption of anticoagulation with warfarin (hazard ratio [HR] 0.76; 95% confidence interval [CI] 0.59–0.97) or dabigatran (HR 0.66; 95% CI 0.44–0.99) was associated with lower combined risk of ischemic stroke and all-cause mortality than anticoagulation discontinuation. The incidence of recurrent major bleeding was higher for patients prescribed warfarin after the event than for those prescribed dabigatran (HR 2.31; 95% CI 1.19–4.76) or whose anticoagulation ceased (HR 1.56; 95% CI 1.10–2.22), but did not differ between patients restarting dabigatran and those discontinuing anticoagulation (HR 0.65; 95% CI 0.32–1.33).

Conclusions—
Dabigatran was associated with a superior benefit/risk ratio than warfarin and anticoagulation discontinuation in the treatment of atrial fibrillation patients who have survived a major bleed.
Normative Pluralism
Authors: Salazar Mónica Gómez 
Published: December 2016

This article suggests that an epistemological and ontological pluralist perspective may enable human beings to cooperate each other and live with less injustice. Intercultural cooperation may help for a reformulation of the Human rights in order to consider aspects of different ways of life like the variations of moral, political and judicial norms. I expound that Liberal pluralism does not respond adequately to present day multiculturalism. Additionally, I explain that Human rights are not inclusive norms for all ways of life.I definitely sustain that some communities do not have to agree to live in the same moral world as others, but, that it is indeed necessary to know each other’s differences so as to be able to respect them.
Criminal Logistics
Authors: Stougaard-Nielsen Jakob 
Published: December 2016

This article investigates how globalized crime fiction is entangled in the infrastructural system of containerization and the production of our global age. My main examples are two widely circulated Danish contributions, namely Peter Høeg’s hybrid crime novel, Miss Smilla’s Feeling for Snow (1992), and the TV-crime series, The Killing III (2012). Generally considered as contained by the regional moniker of “Nordic noir” these crime narratives can be seen to explore global “criminal logistics” (e.g. transportation networks, containerization, colonial administration, drugs and human trafficking, global capitalism) and their impact on the smaller local scales of states, families and victimized children. Conversely, with reference to David Simon’s The Wire (2002–8), the article considers how this “scale bending” between the local and the global is reproduced in the “down-sizing” of Ancient Greek myths and tragedies into the briefest but also most visible of citations on the hull of the ships at the centre of these transnational Danish crime narratives.
Revision of the genus Odocnemis Allard, 1876 (Coleoptera: Tenebrionidae: Helopini) from Turkey, the Caucasus and Iran with observations on feeding habits
Authors: NABOZHENKO MAXIM , KESKIN BEKIR 
Published: December 2016

A revision of the genus Odocnemis of Turkey, the Caucasus and Iran is presented. Thirty species and four subspecies are distributed in this territory. The following 20 new species and subspecies are described: O. dichroa sp. n., O. allardi sp. n., O. merkli sp. n., O. seducta sp. n., O. aegaeica sp. n., O. euritopica sp. n., O. subtuberculigera sp. n., O. subtuberculigera thracica subsp. n., O. erseni sp. n., O. molecularica sp. n., O. shokhini sp. n., O. inornata sp. n., O. altimontana sp. n., O. amanosica sp. n., O. cordiformis sp. n., O. kakunini sp. n. O. evestigata sp. n., O. torosica sp. n., O. torosica subangulata subsp. n., Odocnemis hakkariensis sp. n. The name of the genus is feminine, therefore all species names are transformed from masculine to feminine. Almost all new taxa are described from Turkey; O. amanosica sp. n. is additionally recorded from Syria, O. allardi sp. n.—from Armenia, Azerbaijan (Nakhchivan) and Iran, O. kakunini sp. n. from Iran. New synonymies are established: Odocnemis anatolica (Pic, 1899) = Stenomax korbi Reitter 1902: 219, syn.n.; Odocnemis recticollis (Allard, 1877) = Stenomax kurdistanus Reitter, 1902: 221, syn.n.; Odocnemis punctata Allard, 1876 = Cylindronotus (Odocnemis) pseudoclarus Reitter, 1922, syn.n. The following lectotypes are designated: Helops (Odocnemis) anatolicus Pic, 1899, Helops (Stenomax) seriegranatus Seidlitz, 1896, Cylindronotus (Odocnemis) opertus Reitter, 1922, Stenomax recticollis Allard, 1876, Odocnemis punctata Allard, 1876, Helops (Odocnemis) protinus Reitter in Bodemeyer, 1900. Holotypes and paratypes of all other Turkish species of Odocnemis are studied. Two new combinations are established: Odocnemis gloriosa (Faldermann, 1837), comb. n. (from Nalassus Mulsant, 1854) and Odocnemis terminasianae (Nabozhenko, 2011), comb. n. (from Armenohelops Nabozhenko, 2002). Five species O. bosphoranus (Allard, 1876), O. amasiae (Seidlitz, 1896), O. scutellatus (Reitter, 1902), O. fundator (Reitter, 1908), O. strangulatus (Reitter, 1922)) are not revised in this work and will be included in the genus Armenohelops in a future revision. Three species which were previously recorded from Turkey erroneously (O. exarata (Germar, 1817), O. crenatostriata (Allard, 1877), O. caudata Allard, 1876) should be removed from the Turkish list. Eight species-groups are characterized in the paper. The following aspects are considered and discussed: classification of the genus, morphology and main evolutionary tendencies, distribution and bionomics. A key to the Turkish, Caucasian and Iranian species of Odocnemis is given.
Can we make a better match or mismatch with KIR genotyping?
Authors: Mehta Rohtesh S. , Rezvani Katayoun 
Published: December 2016

AbstractNatural killer (NK) cell function is regulated by a fine balance between numerous activating and inhibitory receptors, of which killer-cell immunoglobulin-like receptors (KIRs) are among the most polymorphic and comprehensively studied. KIRs allow NK cells to recognize downregulation or the absence of HLA class I molecules on target cells (known as missing-self), a phenomenon that is commonly observed in virally infected cells or cancer cells. Because KIR and HLA genes are located on different chromosomes, in an allogeneic environment such as after hematopoietic stem cell transplantation, donor NK cells that express an inhibitory KIR for an HLA class I molecule that is absent on recipient targets (KIR/KIR-ligand mismatch), can recognize and react to this missing self and mediate cytotoxicity. Accumulating data indicate that epistatic interactions between KIR and HLA influence outcomes in several clinical conditions. Herein, we discuss the genetic and functional features of KIR/KIR-ligand interactions in hematopoietic stem cell transplantation and how these data can guide donor selection. We will also review clinical studies of adoptive NK cell therapy in leukemia and emerging data on the use of genetically modified NK cells that could broaden the scope of cancer immunotherapy.
Role of the intestinal mucosa in acute gastrointestinal GVHD
Authors: Peled Jonathan U. , Hanash Alan M. , Jenq Robert R. 
Published: December 2016

Abstract
Intestinal graft-versus-host disease (GVHD) remains a significant obstacle to the success of allogeneic hematopoietic cell transplantation. The intestinal mucosa comprises the inner lining of the intestinal tract and maintains close proximity with commensal microbes that reside within the intestinal lumen. Recent advances have significantly improved our understanding of the interactions between the intestinal mucosa and the enteric microbiota. Changes in host mucosal tissue and commensals posttransplant have been actively investigated, and provocative insights into mucosal immunity and the enteric microbiota are now being translated into clinical trials of novel approaches for preventing and treating acute GVHD. In this review, we summarize recent findings related to aspects of the intestinal mucosa during acute GVHD.
Novel agents in chronic lymphocytic leukemia
Authors: Lamanna Nicole , O’Brien Susan 
Published: December 2016

Abstract
The advent of novel small-molecule inhibitors has transformed the treatment approaches for patients with chronic lymphocytic leukemia (CLL). These therapies are becoming increasingly used in patients with relapsed disease, patients with 17p deletion, and, as of recently, also in the frontline setting for previously untreated patients with CLL. Moreover, many of these are oral therapies that are significantly less myelosuppressive than chemoimmunotherapy. However, these agents have their own set of unique toxicities with which providers must gain familiarity. There is also ongoing development of second-generation agents which have the promise of less toxicity than the US Food and Drug Administration (FDA)–approved compounds. In addition, immunotherapy and the role of the microenvironment are becoming increasingly important and have therapeutic implications in the treatment of patients with CLL. Ultimately, investigators need to evaluate how to position these and other new exciting therapies and decide on the ultimate role for chemoimmunotherapy in modern times.