bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graduate nurses' experiences of mental health services in their first year of practice: An integrative review
Authors: Hooper Mary‐Ellen , Browne Graeme , O'Brien Anthony Paul 
Published: February 2016

AbstractNew graduate nurses have reported negative experiences in mental health settings, particularly during the transitional period of practice. Previous research has focused on addressing the undergraduate preparation of nurses for practice instead of the experiences and outcomes of the transitional period. Recently, there has been growing interest in exploring the experiences of graduate nurses in transition and the implementation of promising interventions to facilitate new graduates' assimilation to practice. Despite these initiatives, the overall shortage of mental health nurses continues to rise, and graduates still report negative experiences in the mental health setting. The purpose of this study was to identify and explore the experiences of new graduate nurses in mental health services in their first year of clinical practice. An integrative review was conducted with 22 studies sourced from the CINAHL, PubMed, Scopus, and PsychINFO electronic databases, as well as through hand‐searching the literature. Literature review findings have highlighted negative clinical experiences and increased attrition from mental health services for graduate nurses. These experiences were closely linked with the changes in the training of mental health nurses, role ambiguity, inadequate clinical preceptorship, encountering the reality of mental health services, and the role of health services in transitioning graduate nurses into clinical practice. Established research into organizational cultures demonstrates that negative organizational outcomes result from negative workplace experiences. Therefore, further research into new graduate nurses' experiences of mental health nursing and its culture might clarify the reasons why they might not be attracted to the discipline and/or are leaving early in their career.
‘People look down on you when you tell them how he died’: Qualitative insights into stigma as experienced by suicide survivors
Authors: Peters Kath , Cunningham Colleen , Murphy Gillian , Jackson Debra 
Published: February 2016

AbstractThis paper aims to present findings that convey how people felt stigmatized after the loss of a loved one to suicide. A qualitative design was used for the purpose of this study. Data were collected using in‐depth, face‐to‐face interviews. Audio‐recordings of the interviews were transcribed and thematically analyzed. Ten people bereaved by suicide participated in the study. Four themes emerged from the data namely: Feeling blamed, shamed and judged; Feeling isolated/rejected by friends and community; Feeling silenced and Feeling the burden of others' discomfort. Findings show that stigmatization of the bereaved by suicide had detrimental effects on their relationships and their help seeking behaviours. Further, due to stigma imposed on them by others, participants were denied the opportunity to tell their stories which further complicated their grieving process. Further education and training is required for health professionals to enhance understanding of the specific needs of those bereaved by suicide.
Understanding the influence of absorptive capacity and ambidexterity on the process of business model change – the case of on‐premise and cloud‐computing software
Authors: Kranz Johann J. , Hanelt André , Kolbe Lutz M. 
Published: February 2016

AbstractThe increasing popularity of Software as a Service has strongly affected the established business model of on‐premise enterprise software. Software as a Service has distinctive characteristics of disruptive innovations that typically create several difficulties for incumbent firms, in particular with regard to adapting business models. To date, however, little empirical understanding exists regarding the dynamics of business model change – a topic of special importance to the highly dynamic software industry, which is characterised by rapid and regular emergence of disruptive innovations. As disruptive innovations require gathering distant knowledge and experimenting with new ideas, this study addresses theoretical gaps regarding the role of absorptive capacity and organisational ambidexterity in the process of business model change owing to the emergence of a disruptive innovation. Drawing on evidence from multiple case studies of six incumbent vendors of enterprise resource‐planning software and informed by a thorough review of related secondary data, we investigate the pace and path of incumbents' business model adaptations. We propose a theoretical model that refines prior literature on absorptive capacity and organisational ambidexterity, particularly with regard to the process of business model change. This study identifies further technological factors that determine how and why incumbents change business models. In addition, our study provides in‐depth insights on the technological trajectory of enterprise resource‐planning software switching from on‐premise to on‐demand software services. © 2016 Blackwell Publishing Ltd
Towards Enhancement of Early‐Stage Chilling Tolerance and Root Development in Sorghum F1 Hybrids
Authors: Windpassinger S. , Friedt W. , Deppé I. , Werner C. , Snowdon R. , Wittkop B. 
Published: February 2016

AbstractSorghum (Sorghum bicolor L. Moench) is regarded a drought‐tolerant alternative to maize as a bioenergy and fodder crop, but its early‐stage chilling sensitivity is obstructing a successful implementation in temperate areas. While several studies have identified quantitative trait loci (QTL) underlying chilling tolerance‐related traits in sorghum lines, little is known about the inheritance of these traits in F1 hybrids. We have conducted a comprehensive approach to analyse heterosis, combining ability and the relation between line per se and hybrid performance for emergence and early shoot and root development comprising both field trials and controlled environment experiments including chilling tests. To our best knowledge, this is the first study analysing heterosis for sorghum root parameters under chilling. Our results show that most traits are heterotic and that the mid‐parent values are rather poor predictors of hybrid performance. Hybrid breeding programmes should focus on efficient GCA tests and the establishment of genetically diverse pools to maximise heterosis rather than on a too strict selection among lines based on their per se performance. The medium‐to‐high heritabilities estimated for seedling emergence and juvenile biomass suggest that a robust breeding progress for these complex traits is feasible.
Instantiating informatics in nursing practice for integrated patient centred holistic models of care: a discussion paper
Authors: Hussey Pamela A. , Kennedy Margaret Ann 
Published: February 2016

AbstractAimA discussion on how informatics knowledge and competencies can enable nursing to instantiate transition to integrated models of care.BackgroundCosts of traditional models of care are no longer sustainable consequent to the spiralling incidence and costs of chronic illness. The international community looks towards technology‐enabled solutions to support a shift towards integrated patient‐centred models of care.DesignDiscussion paper.Data sourcesA search of the literature was performed dating from 2000–2015 and a purposeful data sample based on relevance to building the discussion was included.DiscussionThe holistic perspective of nursing knowledge can support and advance integrated healthcare models. Informatics skills are key for the profession to play a leadership role in design, implementation and operation of next generation health care. However, evidence suggests that nursing engagement with informatics strategic development for healthcare provision is currently variable.Implications for nursingA statistically significant need exists to progress health care towards integrated models of care. Strategic and tactical plans that are robustly pragmatic with nursing insights and expertise are an essential component to achieve effective healthcare provision. To avoid exclusion in the discourse dominated by management and technology experts, nursing leaders must develop and actively promote the advancement of nursing informatics skills. For knowledge in nursing practice to flourish in contemporary health care, nurse leaders will need to incorporate informatics for optimal translation and interpretation.ConclusionDefined nursing leadership roles informed by informatics are essential to generate concrete solutions sustaining nursing practice in integrated care models.
Personal Sovereignty and Our Moral Rights to Non‐Interference
Authors: Burri Susanne 
Published: February 2016

AbstractIn this article, I defend the inviolability approach to solving the paradox of deontology against a criticism raised by Michael Otsuka.The paradox of deontology revolves around the question whether it should always be permissible to infringe someone's right to non‐interference when this would serve to minimize the overall number of comparable rights infringements that occur. According to the inviolability approach, rights to non‐interference protect and give expression to our personal sovereignty, which is not advanced through the minimization of rights infringements. This seems to dissolve the paradox. Otsuka, however, contends that the proposed solution relies on too narrow an understanding of personal sovereignty. He argues that there is an enforceability dimension to personal sovereignty that would seem to undermine the inviolability approach.While I agree with Otsuka that enforceability is an important aspect of personal sovereignty, I argue that properly construed, the enforceability dimension of personal sovereignty does not undermine the inviolability approach.
Toxic Funding? Conflicts of Interest and their Epistemological Significance
Authors: Almassi Ben 
Published: February 2016

AbstractConflict of interest (COI) disclosure has become a routine requirement in communication of scientific information. Its advocates defend COI disclosure as a sensible middle path between the extremes of categorical prohibition on for‐profit research and anything‐goes acceptance of research regardless of origin. To the extent that COI information is meant to aid reviewer and reader evaluation of research, COIs must be epistemologically significant. While some commentators treat COIs as always relevant to research credibility, others liken the demand for disclosure to an ad hominem attack, impugning integrity when better evidence of research credibility is available. Kevin Elliott has argued for clearer justification of COI relevance to research credibility: some interests may be feared to corrupt research results, while others do not, and Elliott provides criteria to discern which financial COIs are actually relevant to research credibility. In this article, I seek to revise and extend Elliott's proposed criteria to COIs more widely. Specifically, I consider the relevance of financial interests as well as nonfinancial advocacy interests to the credibility of research into environmental equity as funded by industry and community groups, with particular attention to criticism and defence of the 1987 United Church of Christ study on the racial demographics of toxic waste facility siting in the United States.
The Choice of Debt Source by UK Firms
Authors: Marshall Andrew , Mccann Laura , Mccolgan Patrick 
Published: February 2016

AbstractWe examine the choice of borrowing source among public debt, syndicated bank loans, bilateral bank loans and non‐bank private debt. Using a sample of 400 non‐financial firms over the period 2000–2012, we find strong support for the reputational theory of borrowing source. Larger firms are more likely to borrow in public debt markets. Bank dependent firms are less likely to borrow in public debt markets and choose between bank and non‐bank private debt based on maturity, collateral available to lenders and other firm characteristics. These results are consistent with the role of borrower reputation being the primary determinant of borrowing source for UK listed firms.
Does the Riskiness of R&D Outweigh Its Benefits? The Perspective of US Private Lenders
Authors: Ciftci Mustafa , Darrough Masako 
Published: February 2016

AbstractWe investigate the relationship between R&D investments and loan spread. Prior research documents that R&D is associated with greater future benefits and risks, suggesting that the valuation of R&D depends on a tradeoff between the two. Some research finds that bondholders consider that the benefits of R&D outweigh its risks: R&D is negatively associated with bond yields. This is surprising given that debt holders are more concerned about downside risk due to asymmetric payoffs. Using data on private debt from the US, we find an overall positive association between loan spread and R&D intensity, suggesting that the riskiness of R&D appears to outweigh its benefits for private lenders. Furthermore, an asymmetric payoff structure implies that the risks of R&D for lenders increase with default risk. Consistent with this argument, we find a positive association between R&D and loan spread for firms that are smaller, with high default‐risk ratings, unrated (no public debt), or in industries with weaker legal protection. Unrated firms are in the most R&D‐intensive group and make up nearly 60% of the firms with private debt. Consequently, studies that exclude unrated firms are likely to present an incomplete picture of the perspective of debt holders on R&D.
Updating the Europe–Africa small mammal exchange during the late Messinian
Authors: García‐Alix Antonio , Minwer‐Barakat Raef , Martín Suárez Elvira , Freudenthal Matthijs , Aguirre Julio , Kaya Ferhat 
Published: February 2016

AbstractAimThe Messinian salinity crisis (MSC) was an extraordinary geological event that affected the whole Mediterranean region as well as the global marine circulation between 5.97 and c. 5.33 Ma. One of its most direct effects was the emersion of land masses and the subsequent establishment of land bridges that led to common terrestrial faunal exchanges. However, the details of the onset of these exchanges have been a matter of controversy. New findings from southern Iberia of small mammal remains with African similarities have enabled us to review the Messinian faunal exchanges in the Mediterranean region.LocationMediterranean region.MethodsSmall mammal remains with African similarities from two new southern Iberian sites were studied. The small mammal associations of eight Miocene–Pliocene North African sites were also reviewed.ResultsTwo taxa with African similarities were identified at the Iberian study sites: Debruijnimys almenarensis and a Ruscinomys‐like form (cf. Ruscinomys) with a strong spur in the lingual lobe of the anterocone in the M1, a feature observed in North African Ruscinomys and eastern Mediterranean Byzantinia. The taxonomic status of some North African species and/or genera, such as Castillomys, Occitanomys and Prolagus, should be revised according to the new phylogenetic relationships established in European faunas.Main conclusionsTwo hypotheses can be proposed for the origin of the African Ruscinomys: (1) among the Iberian Ruscinomys or (2) from the eastern Mediterranean Byzantinia. Our data, currently from only a few, albeit significant, taxa, tend to support an Iberian origin. The discussion presented in this paper suggests an age near the closure of the last Betic Gateway (c. 6.18 Ma) for the first small mammal exchange between Africa and Europe, as well as a single migratory wave of small mammals, filtered by their ecological preferences from this point until the end of the MSC.
Nocturnal Hypertension and Subclinical Cardiac and Carotid Damage: An Updated Review and Meta‐Analysis of Echocardiographic Studies
Authors: Cuspidi Cesare , Sala Carla , Tadic Marijana , Gherbesi Elisa , Grassi Guido , Mancia Giuseppe 
Published: February 2016

Evidence on the association of nocturnal hypertension (NH) with subclinical cardiac and vascular damage is scanty. The authors performed a meta‐analysis to provide comprehensive information on this clinically relevant issue. Full articles providing data on subclinical cardiac and carotid damage as assessed by ultrasonographic methods in patients with NH as compared with patients with nocturnal normotension (NN) were considered. A total of 3657 patients (NH=2083, NN=1574) of both sexes were included in seven studies. Left ventricular mass index was higher in individuals with NH than in those with NN (112±4.7 g/m2 vs 98±4.8 g/m2; standard mean difference [SMD], 0.54±0.16; confidence interval [CI], 0.23–0.85; P<.01). Similarly, common carotid intima‐media thickness was greater in patients with NH than in those with NN (751±34 μm vs 653±14 μm; SMD, 0.44±0.08; CI, 0.29–0.59; P<.01). The present meta‐analysis shows an association between NH pattern and increased likelihood of cardiac and carotid structural alterations.
Release Properties and Stability of Double W1/O/W2 Emulsions Containing Pumpkin Seed Oil
Authors: Ilić Jelena D. , Nikolovski Branislava G. , Lončarević Ivana S. , Petrović Jovana S. , Bajac Branimir M. , Vučinić‐Vasić Milica 
Published: February 2016

AbstractThe double Water‐in‐Oil‐in‐Water emulsions containing a mixture of pumpkin seed and sunflower oil were prepared with polyglycerol polyricinoleate (PGPR) as a hydrophobic emulsifier and different hydrophilic emulsifiers, whereby Tween 20 showed the best stabilization effects. Two different stabilization methodologies of the Water‐in‐Oil emulsions, (1) stabilization against molecular diffusion degradation (Oswald ripening) by electrolyte (NaCl) addition and (2) gelling of internal water droplets using alginate to form gel phase were employed. Emulsion with co‐stabilizer was more stable during storage and heating/freezing treatment than Gel‐in‐Oil emulsions.Glucose was introduced as a thickening agent in the external water phase. The regulation of the osmotic pressures between the water compartments by glucose addition to the external water phase can be employed to modulate the release behavior of encapsulated material and improve the droplet stability. Also, simple correlation was proposed to predict the release fraction of the salt toward the external water phase.Practical ApplicationsDue to their low stability the double emulsions are rarely able to overcome the research phase and to this day have not been converted into commercial products. However, as carriers for the preservation of sensitive components from the environmental exposure destruction, emulsions can provide long term retention of encapsulated material and allow the production of low calorie food products. The incorporation of pumpkin seed oil in the double emulsions due to a multitude of valuable components in its composition contributes to nutritional value of products, making in this way designed emulsions a good base for the preparation of the functional food. Second, encapsulation of salt in double emulsions, except the practical application for the preparation of salted creams, enhances the stability of the emulsions and gives the possibility of tracking the release of hydrophilic material from internal water phase.
Radiotherapy for persistent malignant transformation from mature cystic teratoma of the ovary
Authors: Yoshida Kosuke , Kajiyama Hiroaki , Utsumi Fumi , Mitsui Hiroko , Shibata Kiyosumi , Kikkawa Fumitaka 
Published: February 2016

AbstractMalignant transformations of mature cystic teratomas (MCT) are extremely rare and most of them are squamous cell carcinomas (SCC). Therefore no effective postoperative treatment has been established. In this article, we report two cases in which radiotherapy was effective for SCC arising from MCT. Case 1 was a 64‐year‐old woman with stage IIA of this tumor. After primary surgery, chemotherapy and interval debulking surgery were performed. She received radiotherapy for relapsed tumors, and has been well for 36 months since the initial diagnosis. Case 2 was a 37‐year‐old woman with stage IIB of this tumor. After primary debulking surgery, she received chemoradiotherapy for a residual tumor and has been well for 27 months since the surgery. Although there is no established therapy, radiotherapy or concurrent chemoradiotherapy might have beneficial effects on this tumor, similarly to those on SCC from other tissue.
Prevalence of very low birthweight, malformation, and low Apgar score among newborns inBrazilaccording to maternal urban or rural residence at birth
Authors: Rezende Chrisman Juliana , Mattos Inês Eschenique , Koifman Rosalina Jorge , Koifman Sergio , Moraes Mello Boccolini Patricia , Meyer Armando 
Published: February 2016

AbstractAimAdverse birth outcomes are a major public health issue in rural areas, where several environmental risk factors, including pesticides, may endanger the health of women of reproductive age. We investigated the prevalence of selected birth outcomes among newborns from mothers living in urban and rural areas of aBrazilianmunicipality.MethodsInformation about all live births that occurred between 2004 and 2006 in the Municipality of Nova Friburgo,Brazil, was retrieved from the Live Birth Information System. Newborns were classified as rural or urban, according to the mother's residence address.ResultsNewborns from rural areas had a higher prevalence of very low‐birthweight, low Apgar score, and malformation. On Poisson regression with adjustment for several confounders, rural offspring were more likely to have the aforementioned outcomes.ConclusionsWomen in rural areas are at higher risk of giving birth to an infant with very low‐birthweight, low 5‐min Apgar score and malformations detectable at birth, regardless of socioeconomic and gestational conditions.
Survey of prenatal testing for genetic disorders in Japan: Recent report
Authors: Nobuzane Takahiro , Yamada Takahiro , Miura Kiyonori , Sawai Hideaki , Masuzaki Hideaki , Kudo Yoshiki 
Published: February 2016

AbstractAimIn order to investigate the current status of prenatal testing for genetic disorders, we conducted a multicenter retrospective questionnaire survey.MethodsThe questionnaire was sent to 105 facilities with genetic counseling systems. The questionnaire consisted of two parts: (i) the number of prenatal tests conducted for genetic disorders from January 2010 to December 2012, whether the laboratory was combined with the counseling facility or separate, the sampling procedure method, the testing results, and the outcomes of the affected fetus in addition to treatment; and (ii) a survey of personal comments regarding prenatal testing for genetic disorders.ResultsWe received responses from 69 of the 105 facilities (65.7%), and genetic testing was performed at 26 of these facilities. Nucleic acid sequential testing was performed on 45 disorders and 252 cases during a three‐year period. There were 67 cases of affected fetuses. Six cases continued pregnancy and were treated. The comment survey highlighted difficulties in locating a laboratory to assess prenatal samples, as well as inadequate counseling and preparation for genetic disorders.ConclusionsOur study revealed that a number of prenatal testing for genetic disorders are conducted in Japan; however, it is difficult for counselors to locate a laboratory capable of testing for specific genetic disorders. Inadequate counseling and healthcare providers' lack of knowledge is a current problem. A well‐established system of prenatal testing for genetic disorders and the further education of general physicians is required.