bluuebunny/crossref_metadata_2025_split huggingface dataset:
(CH3NH3)2PdCl4: A Compound with Two‐Dimensional Organic–Inorganic Layered Perovskite Structure
Authors: Huang Tang Jiao , Thiang Zhang Xian , Yin Xuesong , Tang Chunhua , Qi Guojun , Gong Hao 
Published: January 2016

AbstractThe synthesis of previously unknown perovskite (CH3NH3)2PdCl4 is reported. Despite using an organic cation with the smallest possible alkyl group, a 2D organic–inorganic layered Pd‐based perovskites was still formed. This demonstrates that Pd‐based 2D perovskites can be obtained even if the size of the organic cation is below the size limit predicted by the Goldschmidt tolerance‐factor formula. The (CH3NH3)2PdCl4 phase has a bulk resistivity of 1.4 Ω cm, a direct optical gap of 2.22 eV, and an absorption coefficient on the order of 104 cm−1. XRD measurements suggest that the compound is moderately stable in air, an important advantage over several existing organic–inorganic perovskites that are prone to phase degradation problems when exposed to the atmosphere. Given the recent interest in organic–inorganic perovskites, the synthesis of this new Pd‐based organic–inorganic perovskite may be helpful in the preparation and understanding of other organic–inorganic perovskites.
Gold‐Catalyzed Tandem Cycloisomerization–Halogenation of Chiral Homopropargyl Sulfonamides
Authors: Shu Chao , Li Long , Shen Cang‐Hai , Ruan Peng‐Peng , Liu Chao‐Yue , Ye Long‐Wu 
Published: January 2016

AbstractTwo new gold‐catalyzed tandem cycloisomerization–halogenation reactions of chiral homopropargyl sulfonamides have been developed. Various enantioenriched 3,3‐diiodopyrrolidin‐2‐ols and 3‐fluoropyrrolidin‐2‐ols were obtained in moderate‐to‐good yields with excellent enantio‐ and diastereoselectivity.
Coated/Sandwiched rGO/CoSx Composites Derived from Metal–Organic Frameworks/GO as Advanced Anode Materials for Lithium‐Ion Batteries
Authors: Yin Dongming , Huang Gang , Zhang Feifei , Qin Yuling , Na Zhaolin , Wu Yaoming , Wang Limin 
Published: January 2016

AbstractRational composite materials made from transition metal sulfides and reduced graphene oxide (rGO) are highly desirable for designing high‐performance lithium‐ion batteries (LIBs). Here, rGO‐coated or sandwiched CoSx composites are fabricated through facile thermal sulfurization of metal–organic framework/GO precursors. By scrupulously changing the proportion of Co2+ and organic ligands and the solvent of the reaction system, we can tune the forms of GO as either a coating or a supporting layer. Upon testing as anode materials for LIBs, the as‐prepared CoSx‐rGO‐CoSx and rGO@CoSx composites demonstrate brilliant electrochemical performances such as high initial specific capacities of 1248 and 1320 mA h g−1, respectively, at a current density of 100 mA g−1, and stable cycling abilities of 670 and 613 mA h g−1, respectively, after 100 charge/discharge cycles, as well as superior rate capabilities. The excellent electrical conductivity and porous structure of the CoSx/rGO composites can promote Li+ transfer and mitigate internal stress during the charge/discharge process, thus significantly improving the electrochemical performance of electrode materials.
A New Approach for the Synthesis of Highly Substituted Aromatic Rings: The Alkyne‐Mediated Approach
Authors: Parsons Philip J. , Jones Daniel R. , Padgham Alex C. , Allen Lewis A. T. , Penkett Clive S. , Green Robert A. , White Andrew J. P. 
Published: January 2016

AbstractPentasubstituted aromatic rings serve as templates for drug design and can be conveniently prepared by the thermolysis of suitably substituted alkynes under microwave conditions.
Total Synthesis of the Antiviral Natural Product Houttuynoid B
Authors: Kerl Thomas , Berger Florian , Schmalz Hans‐Günther 
Published: January 2016

AbstractThe first total synthesis of houttuynoid B, a powerful antiviral flavonoid glycoside from the Chinese plant Houttuynia cordata, is described. In a key step, a Baker–Venkataraman rearrangement employing an already glycosylated substrate was used to efficiently set up the fully functionalized carbon skeleton. The required benzofuran building block was prepared through a domino Sonogashira coupling/5‐endo‐dig cyclization and converted into a stable 1‐hydroxybenzotriazole‐derived active ester prior to linking with a galactosylated hydroxyacetophenone unit. The elaborated synthesis requires only nine steps (11 % overall yield) along the longest linear sequence and paves the way for the preparation of structurally related compounds for further biological evaluation.
Nonlinear Optical Properties of Porphyrin Derivatives with Electron‐donating or Electron‐withdrawing Substituents
Authors: Liang Pengxia , Mi Yongsheng , Duan Jinshuai , Yang Zhou , Wang Dong , Cao Hui , He Wanli , Yang Huai 
Published: January 2016

AbstractTo investigate photoelectric properties of meso‐extended porphyrin derivatives with electron‐donating or electron‐withdrawing substituents, a series of functionalized porphyrin materials have been designed and synthesized by Suzuki coupling reaction. The meso‐extended structures were fully characterized by 1H NMR, IR spectroscopy and mass spectrometry. The photophysical properties of porphyrin derivatives were carefully examined by UV‐Visible and fluorescence spectra, and the solvatochromic effect was observed and discussed. In particular, Z‐scan technique was employed to characterize the third‐order nonlinear optical (NLO) properties of the products such as nonlinear absorption and refraction, the third‐order nonlinear refractive indexes (𝔵(3)‐value) of these porphyrin derivatives achieved 3.9×10−12 esu. In addition, the compounds could be self‐assembled into highly organized morphologies through phase‐exchange method. All the results indicated that the discotic materials have the potential for optoelectronic applications.
Mn‐Based Two Dimensional Metal‐Organic Framework Material from Benzimidazole‐5,6‐dicarboxylic Acid
Authors: Zhang Erpan , Zhang Lili , Tan Zhe , Ji Zhenguo , Li Qiaowei 
Published: January 2016

AbstractA new two‐dimensional metal‐organic framework (MOF) structure has been synthesized by mild solvothermal reaction of MnCl2·4H2O with 1H‐benzimidazole‐5,6‐dicarboxylic acid (H3bidc) at 85°C. The structure has been characterized by single‐crystal X‐ray diffraction, powder X‐ray diffraction (PXRD), infrared spectroscopy (FT‐IR), and thermogravimetric analysis (TGA). Single‐crystal X‐ray diffraction analysis revealed that this MOF is a five‐coordinated Mn(II) compound exhibiting a layered 2D network, in which the hydrogen‐bonding interactions between uncoordinated carboxylic oxygen atoms and NH groups in the imidazole rings play a key role in the final 3D supramolecular architecture. This MOF shows high thermal stability up to 400°C. Furthermore, XRD pattern of the MOF structure was retained for up to 20 d after soaked in water, and only 2.8 wt% of the MOF was decomposed within the first 48 h in water.
Inclusion Complex of Podophyllotoxin with γ‐Cyclodextrin: Preparation, Characterization, Anticancer Activity, Water‐Solubility and Toxicity
Authors: Guo Yafei , Zhang Yushun , Li Jiuling , Zhao Fen , Liu Yang , Su Min , Jiang Yubo , Liu Yuqi , Zhang Jihong , Yang Bo , Yang Rui 
Published: January 2016

AbstractAn inclusion complex of podophyllotoxin (PPT) with γ‐cyclodextrin (γ‐CD) was prepared. The behavior, characterization, and water solubility of the inclusion complex were carefully investigated via fluorescence spectroscopy, thermogravimetry, differential scanning calorimetry, X‐ray diffraction analysis, and 1H and 2D nuclear magnetic resonance spectroscopy. Furthermore, antitumor activity to human cancer lines and toxicity in mice were studied. Results showed that the inclusion complex formed in a 1:1 ratio with a considerable apparent stability constant Ks (4245.5 L·mol−1). Water solubility was considerably improved. In addition, the anticancer activity of the inclusion complex was better than that of cis‐platinum (DDP, positive control). Most importantly, the toxicity of podophyllotoxin inclusion complex reduced and became more safety to mice which will be great valuable to research its applications as a kind of antitumor drug to human in the further.
An Acetylcholinesterase Biosensor Based on Graphene/Polyaniline Composite Film for Detection of Pesticides
Authors: Li Yanping , Zhang Yuyu , Han Gaoyi , Xiao Yaoming , Li Miaoyu , Zhou Wen 
Published: January 2016

AbstractThis work reports a sensitive amperometric biosensor for organophosphate pesticides (OPs) fabricated through modifying glassy carbon electrode with acetylcholinesterase (AChE) immobilized on graphene/polyaniline (G/PANI) composite film. The obtained G/PANI composite films show large specific area, high conductivity, good biocompatibility, and fast redox properties and have perfect layered and encapsulated structures. The as‐prepared biosensor shows high affinity to acetylthiocholine (ATCl) with a Michaelis‐Menten constant value of 0.20 mmol/L. Furthermore, based on the inhibition of the enzymatic activity (immobilized AChE) caused by the model compound of carbaryl (one kind of pesticides), it is found that the inhibition activity of carbaryl is proportional to its concentration ranging from 38 to 194 ng·mL−1. The developed biosensor shows a detection limit of 20 ng·mL−1 (S/N=3) for OPs detection and exhibits good performance such as good reproducibility and acceptable stability, which makes it possible to provide a new and promising tool for the analysis of enzyme inhibitors.
Palladium Nanoparticles Supported on a Porous Organic Polymer: An Efficient Catalyst for Suzuki‐Miyaura and Sonogashira Coupling Reactions
Authors: Ren Xiaomeng , Kong Shengnan , Shu Qiding , Shu Mouhai 
Published: January 2016

AbstractA new porous organic polymer (POP) with high thermal stability and large surface area has been synthesized and applied in the preparation of Pd/POP catalyst. Pd/POP was characterized by XRD, TGA, SEM and TEM. The catalyst consists of highly dispersed palladium nanoparticles of 0.9–4 nm size on POP with a large surface area of 650 m2/g. It presents high catalytic activity for Suzuki‐Miyaura and Sonogashira reactions. The catalyst was reusable for three to five times without significant loss of activity.
Health‐related quality of life and health care use in cancer survivors compared with patients with chronic diseases
Authors: Heins Marianne J. , Korevaar Joke C. , Hopman Petra E.P.C. , Donker Gé A. , Schellevis François G. , Rijken Mieke P.M. 
Published: January 2016

BACKGROUNDThe number of cancer survivors is steadily increasing and these patients often experience long‐lasting health problems. To make care for cancer survivors sustainable for the future, it would be relevant to put the effects of cancer in this phase into perspective. Therefore, the authors compared health‐related quality of life (HRQOL) and health care use among cancer survivors with that of patients with chronic diseases.METHODSPatients diagnosed at age >18 years with a cancer with a 5‐year survival rate > 20% and no distant metastases at the time of diagnosis and patients aged >18 years with physician‐diagnosed somatic chronic diseases without cancer were sent a questionnaire. HRQOL was measured with the RAND‐36, a measure of HRQOL. Self‐reported health care use was measured for general practitioner care, specialist care, rehabilitative care, physical therapy, ambulatory mental health care, and occupational health care.RESULTSA total of 601 cancer survivors and 1052 patients with chronic diseases without cancer were included in the current study. Multimorbidity was observed in 63% of the cancer survivors and 61% of the patients with chronic diseases. The HRQOL of the cancer survivors was significantly better than that of patients with chronic diseases after adjustment for age and sex. For the mental functioning subscale, no significant differences were found between the 2 groups. Cancer survivors were found to be less likely to have visited a general practitioner or cardiologist compared with patients with chronic diseases.CONCLUSIONSWhen considering physical HRQOL and health care use, cancer survivors appear to fare better than the average patient with chronic diseases. No difference in mental functioning was observed in the current study. Cancer 2016;122:962–70. © 2016 American Cancer Society.
Experimental validation of more realistic computer models for stent‐graft repair of abdominal aortic aneurysms, including pre‐load assessment
Authors: Roy David , Lerouge Sophie , Inaekyan Karina , Kauffmann Claude , Mongrain Rosaire , Soulez Gilles 
Published: January 2016

SummaryAlthough the endovascular repair of abdominal aortic aneurysms is a less invasive alternative than classic open surgery, complications such as endoleak and kinking still need to be addressed. Numerical simulation of endovascular repair is becoming a valuable tool in stent‐graft (SG) optimization, patient selection and surgical planning.The experimental and numerical forces required to produce SG deformations were compared in a range of in vivo conditions in the present study. The deformation modes investigated were: bending as well as axial, transversal and radial compressions. In particular, an original method was developed to efficiently account for radial pre‐load because of the pre‐compression of stents to match the graft dimensions during manufacturing. This is important in order to compute the radial force exerted on the vessel after deployment more accurately.Variations of displacement between the experimental and numerical results ranged from 1.39% for simple leg bending to 5.93% for three‐point body bending.Finally, radial pre‐load was modeled by increasing Young's modulus of each stent. On average, it was found that Young's modulus had to be augmented by a factor of 2. Copyright © 2016 John Wiley & Sons, Ltd.
Temperature‐Dependent Dual Emission from Sucrose‐Derived Carbon Nanodots: A Ratiometric Fluorescent Thermometer
Authors: Gan Zhixing , Hao Yanling , Shan Yun 
Published: January 2016

AbstractCarbon nanodots (CNDs) with conspicuous dual emission (at 450 and 517 nm) were fabricated by hydrothermal treatment of aqueous sucrose solution. The temperature‐dependent photoluminescence (PL) and time‐resolved PL were investigated. The trapping of excited electrons by the nonradiative defects should substantially account for the PL quenching as the temperature increases. The sucrose‐derived CNDs show great potential for applications as ratiometric fluorescent thermometers with a sensitivity of approximately 2.15 % °C−1.
Yellow pigments based on lead, tin, and antimony: Ancient recipes, synthesis, characterization, and hue choice in artworks
Authors: Agresti Giorgia , Baraldi Pietro , Pelosi Claudia , Santamaria Ulderico 
Published: January 2016

AbstractThe aim of this study is to investigate the yellow pigments based on lead, tin, and antimony produced according to the ancient treatises, recipe books, and literary sources. The pigments considered in this study are lead/tin yellow type I (Pb2SnO4), lead/tin yellow type II (PbSn1−xSixO3), lead antimonate or Naples yellow (Pb2Sb2O7), and lead/tin/antimony yellow (Pb2SnSbO6,5). Color was measured by X‐Rite reflectance spectrophotometer to investigate the chromatic characteristics of the produced pigments in relation to the recipes. The pigments were chemically characterized by scanning electron microscopy with energy‐dispersive spectroscopy, and micro‐Raman analysis to investigate the influence of reagents, temperature, and melting modalities in the compositions of the produced powders. A part of the study was devoted to the study on the use of these yellow pigments in the art history especially concerning themodus pingendiof Italian artists between 14th and 18th century. The results of this study highlighted the possibility to obtain pigments with different colors and compositions according to the reagents, to the temperature, to the melting modality, in particular if single or double firing was used. © 2016 Wiley Periodicals, Inc. Col Res Appl, 41, 226–231, 2016
Multi‐analytical approach to the material characterization of 16th century wall paintings from Ribeira Sacra (Galicia, NWSpain): Pictorial palette, technique and alterations
Authors: Pereira‐Pardo Lucía , Gil Milene , Prieto Beatriz , Silva Benita 
Published: January 2016

AbstractThe present work aims to investigate for the first time the materials used in Ribeira Sacra's 16th century murals, as this knowledge would be valuable for research in Technical Art History and for interventions of conservation. A multi‐analytical approach is proposed for the investigation of the pictorial palette and technique, and the degradation products. Technical photography (Vis‐RAK, IR, UV, micro‐photography) and non‐invasive analysis by XRF and Vis‐RS were performed on site. Micro‐samples were taken carefully and studied in the laboratory by means of OM, SEM‐EDX, MRS, FTIR, µ‐XRD, GC‐MS, MALDI‐TOF/TOF, and HPLC‐ESI‐TOF. The analytical results revealed a basic palette of natural red, yellow and brown earth pigments, calcite and several varieties of carbon black. A chromatic enrichment of the palette is observed from the second half of the 16th century, incorporating green, blue and purple colourants. The main pictorial technique is fresco. Some of the pigments, like red lead and azurite, were found altered and the degradation causes and mechanisms were investigated. © 2016 Wiley Periodicals, Inc. Col Res Appl, 41, 263–269, 2016
Hybrid Density Functional Study on Mono‐ and Codoped NaNbO3 for Visible‐Light Photocatalysis
Authors: Wang Guang‐Zhao , Chen Hong , Wu Gang , Kuang An‐Long , Yuan Hong‐Kuang 
Published: January 2016

AbstractMonodoping with Mo, Cr, and N atoms, and codoping with Mo−N and Cr−N atom pairs, are utilized to adjust the band structure of NaNbO3, so that NaNbO3 can effectively make use of visible light for the photocatalytic decomposition of water into hydrogen and oxygen, as determined by using the hybrid density functional. Codoping is energetically favorable compared with the corresponding monodoping, due to strong Coulombic interactions between the dopants and other atoms, and the effective band gap and stability for codoped systems increase with decreasing dopant concentration and the distance between dopants. The molybdenum, chromium, and nitrogen monodoped systems, as well as chromium–nitrogen codoped systems, are unsuitable for the photocatalytic decomposition of water by using visible light, because defects introduced by monodoping or the presence of unoccupied states above the Fermi level, which promotes electron–hole recombination processes, suppress their photocatalytic performance. The Mo−N codoped NaNbO3 sample is a promising photocatalyst for the decomposition of water by using visible light because Mo−N codoping can reduce the band gap to a suitable value with respect to the water redox level without introducing unoccupied states.
Characteristics of the pain tolerance threshold induced by electrical stimulation of the alveolar ridge
Authors: Nakashima Yoshio , Kimoto Suguru , Ogawa Takahiro , Furuse Nobuhiko , Ono Masanori , Kawai Yasuhiko 
Published: January 2016

AbstractThe purpose of this study was to determine the characteristics of the pain tolerance threshold (PTT) induced by electrical stimulation of the alveolar ridge. A total of 100 healthy volunteers studying or working at Nihon University School of Dentistry at Matsudo and patients from Nihon University School of Dentistry at Matsudo Affiliated Hospital, including 51 men (58.7 ± 17.6 years old) and 49 women (60.7 ± 17.1 years old), participated in this study. The volunteers were enrolled after obtaining written informed consent. PTT measurements were obtained using a Neurometer CPT/C® device to deliver electrical stimulation around the left greater palatine foramen at frequencies of 5 and 250 Hz. When the stimulus could no longer be tolerated, the participant released a button to automatically discontinue the stimulus. After the distribution of the PTT values was analyzed, the influence of gender, age, and Eichner index on PTT was analyzed. The Eichner index values were divided into three categories: group A (four supporting zones), group B (less than four supporting zones but with anterior tooth contact), and group C (no occlusal contact). The PTT values did not show a normal distribution. There were no significant differences in PTT between men and women. PTT was significantly associated with age (P = 0.017) at 5 Hz in men. There were no significant differences in PTT among the Eichner index groups. The characteristics of the PTT of the alveolar ridge are as follows: (1) age and PTT at 5 Hz are significantly associated with men but not with women, and (2) the Eichner index has no influence on the PTT.
Resveratrol Ameliorates the Components of Hepatic Inflammation and Apoptosis in a Rat Model of Streptozotocin‐Induced Diabetes
Authors: Pektaş Mehmet Bilgehan , Sadi Gökhan , Koca Halit Bugra , Yuksel Yasemin , Vurmaz Ayhan , Koca Tulay , Tosun Murat 
Published: January 2016

ABSTRACT

Preclinical Research

Trans‐resveratrol has a wide range of biological effects that reflect its antioxidant, anti‐inflammatory, anticarcinogenic and cardioprotective properties. This study was conducted to elucidate the potential role of resveratrol on hepatic inflammation and the apoptotic pathway components Bcl‐2, Bax and p53 in a streptozotocin (STZ)‐induced rat model of diabetes mellitus. Inflammatory and apoptotic biomarkers indicated a reduction in hepatic erythropoietin (1.26‐fold) and increased asymmetric dimethylarginine (3.9‐fold), visfatin (1.6‐fold), inflammatory interleukins and TNF–α contents (approximately twofold each) in the diabetic animals. Induction of inducible nitric oxide synthase gene (2.04‐fold) and protein expression (1.24‐fold) was also observed. Immunohistochemical studies showed enhancement of the apoptotic biomarkers Bax and p53 in diabetic animals. STZ‐induced diabetic male Wistar rats were treated with resveratrol (20 mg/kg/day i.p.). Resveratrol succeeded to recover most of these inflammatory and apoptotic elements. Therefore, inflammatory and apoptotic pathways were proved to be affected by STZ‐induced diabetes in several aspects and resveratrol might contribute hepatoprotective effects as evidenced from this study. Drug Dev Res 77 : 12–19, 2016. © 2016 Wiley Periodicals, Inc.