bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visualizing the fine structure and dynamics of living cells with temporal polychromatic digital holographic microscopy
Authors: Haouat Mohamed , Larivière-Loiselle Céline , Crochetière Marie-Ève , Chaniot Johan , Moreaud Maxime , Bélanger Erik , Marquet Pierre 
Published: October 2024

Polychromatic digital holographic microscopy (P-DHM) has demonstrated its capacity to generate highly denoised optical path difference images, thereby enabling the label-free visualization of fine cellular structures, such as the dendritic arborization within neuronal cells in culture. So far, however, the sample must remain more or less stationary since P-DHM is performed manually, i.e., all actions are carried out sequentially over several minutes. In this paper, we propose fully automated, robust, and efficient management of the acquisition and reconstruction of the time series of polychromatic hologram sets, transforming P-DHM into temporal P-DHM. Experimental results have demonstrated the ability of the proposed temporal P-DHM implementation to non-invasively and quantitatively reveal the fine structure and dynamics of living cells.
Ultralow-noise preamplified optical receiver using conventional single-wavelength transmission
Authors: Larsson Rasmus , Weerasuriya Ruwan U. , Andrekson Peter A. 
Published: October 2024

Conventional optical amplifiers that use stimulated emission suffer from the generation of excess noise, thus limiting the performance in many applications. The phase-sensitive optical parametric amplifier, relying on the use of a nonlinear material for amplification, is an exception that can approach a noise figure of 0 dB. Its implementation in optical communication links has, however, been cumbersome due to increased complexity both in the transmitter and the receiver, effectively limiting the use of such amplifiers in practice. Here, we propose and demonstrate an implementation of a transmission system with exceptional performance in terms of receiver sensitivity (0.9 photons per bit) using a standalone ultralow-noise phase-sensitively preamplified receiver and a conventional single-wave optical transmitter. This is a significant simplification compared to previous demonstrations and can transform such amplifiers from a curiosity to practical use for example in deep-space-to-earth communication links.
Performance and usability of cardiometabolic point of care devices in Nepal: A prospective, quantitative, accuracy study
Authors: Giachino Marina , Vetter Beatrice , Perone Sigiriya Aebischer , Correia Jorge César , Erkosar Berra , Heller Olivia , Khanal Vijay Kumar , Lab Bruno , Pataky Zoltan , Poudel Sagar , Rai Mamit , Sharma Sanjib Kumar 
Published: October 2024

Non-communicable diseases (NCDs), such as cardiovascular disease and diabetes, represent a serious global health concern. There is an urgent need for prompt diagnosis and effective monitoring at point of care, especially in low- and middle-income countries. Here we present the results of a study assessing the quantitative accuracy of two devices that may fit the target product profile for a cardiometabolic point-of-care device. This prospective, quantitative, accuracy study (NCT05257564) was conducted between March to May 2022, investigating the performance of the JanaCare Aina Blood Monitoring System (JCAina) and the Tascom SimplexTAS 101 device (TAS101) compared with local standard laboratory methods in rural Nepal. Using fingerstick capillary blood, cardiometabolic parameters were analysed using both devices. The quantitative accuracy was compared against a local laboratory reference assay. System usability was also assessed. For JCAina, the mean absolute biases (Bland-Altman analysis) for glucose, HbA1c and total cholesterol tests were -3.87 mg/dL (95% CI: -7.52–-0.22), 1.34% (95% CI: 1.21–1.47), and -9.52 mg/dL (95% CI: -11.9–-7.2), respectively, corresponding to mean percentage biases of 2.0%, 18.5%, and -6.4%. These indicate clinically small (<10% biases) differences from laboratory results for glucose and cholesterol, and a moderate (10–20%) positive bias for HbA1c. For TAS101, the mean absolute biases for glucose, HbA1c, total cholesterol and creatinine tests were 18.7 mg/dL (95% CI: 15.8–21.5), -0.2% (95% CI: -0.26–-0.14), 29.8 mg/dL (95% CI: 27.0–32.6), and -0.02 mg/dL (95% CI: -0.05–0.01), respectively, corresponding to mean percentage biases of 12.1%, -2.6%, 15.8%, and -4.5%. These indicate clinically small differences for HbA1c and creatinine, and moderate positive biases for glucose and cholesterol. Both systems exhibited usability challenges. The JCAina and TAS101 point-of-care cardiometabolic devices were shown to have promising accuracy in environmental conditions such as in Nepal, though improvements are still needed for some parameters and for ease of use.
Trial registration: NCT05257564 (ClinicalTrials.gov).
Multivariable modeling: A retrospective cohort study exploring the impact of socioeconomic status and distance to a rural academic center on all-cause preterm delivery
Authors: Darivemula Shilpa , Kouassi-Brou Marilyn , Pollack Catherine , Paris Amy , Goodman Daisy , Fisher Timothy 
Published: October 2024

Objective
Hospital-based labor and delivery units are closing at increasing rates in the rural US, significantly impacting maternal and newborn health. The objective of this study to determine if rurality—measured as distance from the hospital—and socioeconomic status—measured as insurance payor—impact both spontaneous and medically indicated preterm birth incidence at a single rural academic institution.

Methods
This was a retrospective cohort study using electronic medical records of patients with singleton pregnancies delivering at a single rural academic institution between 2016–2018. The primary outcome was preterm delivery (PTD) and secondary outcomes included low birth weight (LBW) and intensive care nursery (ICN) admission. The primary exposures included (1) travel time from a patient’s address to the hospital and (2) insurance carrier as a proxy for socioeconomic status. Bivariate analyses indicated that travel time, insurance status, race, ethnicity, marital status, number of prenatal visits, gravida and para, and smoking status were significant predictors of all outcomes (LBW, ICN admission, and PTD). Therefore, these predictors were included in the multivariable logistic models.

Results
Within the multivariable logistic model, patients traveling 1–1.5 hours had approximately twice the odds of PTD (Odds Ratio, OR: 2.08, 95% Confidence Interval CI, 1.32, 3.29, p = .002), birth of a LBW neonate (OR: 2.15; 95% CI: 1.29–3.58, p = .005), and infant admission to the ICN (OR 1.83, 95% CI: 1.22–2.76, p = .004) compared to patients traveling under 30 minutes,. Insurance carrier status was not associated with increased odds of PTD, LBW, or ICN admission.

Conclusion
Patients living 1-to-1.5 hours from the hospital had an increased risk for LBW, ICN admission, and PTD, despite living in zip codes with less social deprivation than zip codes further away from the hospital.
Respiratory virus behavior: Results of laboratory-based epidemiological surveillance
Authors: Hernández Bautista Porfirio Felipe , Cabrera Gaytán David Alejandro , Vallejos Parás Alfonso , Moctezuma Paz Alejandro , Santacruz Tinoco Clara Esperanza , Alvarado Yaah Julio Elias , Anguiano Hernández Yu Mei , Martínez Miguel Bernardo , Arriaga Nieto Lumumba , Jaimes Betancourt Leticia , Sandoval Gutiérrez Nancy 
Published: October 2024

Background
Respiratory viruses have clinical and epidemiological importance. With the COVID-19 pandemic, interest has focused on SARS-CoV-2, but as a result, the number of samples available for the differential diagnosis of other respiratory viruses has increased.

Study design
Cross-sectional study.

Objective
To describe the epidemiological behavior of respiratory viruses based on a laboratory-based epidemiological surveillance system using data from 2017 to 2023.

Methods
Univariate, bivariate and multivariate analyses of data from a laboratory database of respiratory viruses detected by multiplex RT‒qPCR were performed.

Results
A total of 4,632 samples with positive results for at least 1 respiratory virus, not including influenza or SARS-CoV-2, were analyzed. The most common virus detected was respiratory syncytial virus in 1,467 (26.3%) samples, followed by rhinovirus in 1,384 (24.8%) samples. Most of the samples were from children under 5 years of age. The age-adjusted odds ratio (OR) of death for patients infected with parainfluenza virus 4 was 4.1 (95% confidence interval [95% CI] 2.0–8.2).

Conclusion
Respiratory syncytial virus and rhinovirus had the highest frequency and proportion of coinfections, whereas parainfluenza virus 4 was associated with an increased risk of death.
Pelvic floor dysfunction in postpartum women: A cross-sectional study
Authors: Gao Qian , Wang Mingbo , Zhang Jie , Qing Yangzhe , Yang Ziyi , Wang Xin , Xu Xujuan , Ye Qing , Zhang Feng 
Published: October 2024

Background
Pelvic floor dysfunction (PFD) is a disease of weakened pelvic floor support tissues, leading to changes in the pelvic organ position and function of pelvic organs, with long-term effects on women. This study aimed to assess pelvic floor function using electrophysiology and clinical symptoms, exploring the risk factors for PFD one month postpartum.

Methods
This cross-sectional study included 845 women from postpartum outpatient clinic of Nantong Affiliated Hospital from August 2019 to October 2021. Pelvic floor muscle strength was evaluated via pelvic floor surface electromyography. Clinical symptoms (urinary incontinence (UI) and pelvic organ prolapse) were diagnosed by gynecologists. Sociodemographic, pregnancy, and obstetrical data were obtained from self-reported questionnaires and electronic records.

Results
The study identified maternal age, parity, immigrant status, and economic income as factors were related to PFD. Gestational constipation increased the risk of abnormal resting muscle strength (OR:1.553, 95%CI: 1.022–2.359). Cesarean delivery was associated with higher rates of abnormal resting muscle strength than vaginal delivery (post-resting stage: OR, 2.712; 95% CI, 1.189–6.185), but a decreased incidence of UI (OR: 0.302; 95% CI, 0.117–0.782). Increased gestational weight gain was correlated with a greater risk of developing UI (OR:1.030, 95%CI: 1.002–1.058). Women with vaginal inflammation faced a higher risk of abnormal fast-twitch muscle (OR: 2.311, 95%CI: 1.125–4.748).

Conclusions
In addition to uncontrollable factors like mode of delivery, age, and parity, interventions targeting weight gain and constipation during pregnancy and vaginal flora could mitigate the risks of PFD. Educational programs for pregnant women should emphasize a proper diet and lifestyle. For women with vaginal inflammation, clinical treatment should be carried out as soon as possible to avoid further aggravating the damage to the pelvic floor muscles.
Cardiac prehabilitation, rehabilitation and education in first-time atrial fibrillation (AF) ablation (CREED AF): Study protocol for a randomised controlled trial
Authors: Chandan Nakul , Matthews Violet , He Hejie , Lachlan Thomas , Lim Ven Gee , Joshi Shivam , Hee Siew Wan , Noufaily Angela , Parkes Edward , Patel Shilpa , Andronis Lazaros , Shakespeare Joanna , Eftekhari Helen , Ali Asad , McGregor Gordon , Osman Faizel 
Published: October 2024

Background
Atrial fibrillation (AF) is associated with significant morbidity/mortality. AF-ablation is an increasingly used treatment. Currently, first-time AF-ablation success is 40–80% at 1-year, depending on individual factors. There is growing evidence for improved outcomes through management of AF risk-factors/comorbidities via patient education/exercise-rehabilitation. There are no studies assessing combined prehabilitation/rehabilitation in this cohort. The aim of this randomised controlled trial is to assess efficacy of comprehensive prehabilitation/rehabilitation and combining supervised exercise-training with AF risk-factor modification/education compared with standard care in people undergoing first-time AF ablation.

Methods
This single-centre pragmatic randomised controlled trial will recruit 106 adults with paroxysmal/persistent AF listed for first-time AF-ablation. Participants will be randomised 1:1 to cardiac prehabilitation/rehabilitation/education (CREED AF) intervention or standard care. Both groups will undergo AF-ablation at 8-weeks post-randomisation as per usual care. The CREED AF intervention will involve 6-weeks of prehabilitation (before AF-ablation) followed by 6-weeks rehabilitation (after AF-ablation) consisting of risk factor education/modification and supervised exercise training. Standard care will include a single 30-minute session of risk-factor education. Outcomes will be measured at baseline, 10-weeks and 12-months post AF-ablation, by researchers blinded to treatment allocation. The primary outcome is cardiorespiratory-fitness (peak oxygen uptake, VO2peak) assessed using cardiopulmonary exercise testing (CPET) at 10-weeks post-ablation. Secondary outcomes include health-related quality of life, AF recurrence/burden assessed by 7-day Holter-monitor, requirement for repeat AF-ablation, study defined major adverse cardiovascular events, and cost-effectiveness (incremental cost per quality-adjusted life year (QALY)).

Conclusions
This study will assess clinical-efficacy/cost-effectiveness of comprehensive prehabilitation/rehabilitation/patient-education for people undergoing first time AF-ablation. Results will inform clinical care and design of future multi-centre clinical trials.

Trial registration
URL: https://www.clinicaltrials.gov; Unique identifier: NCT06042231.Date registered: September 18, 2023.
Language teaching in the 21st century: incorporating culturally sustaining pedagogies for social and cognitive justice in education
Authors: Perales-Fernández-de-Gamboa Andrea , Orcasitas-Vicandi María 
Published: October 2024

Abstract
Culturally Sustaining Pedagogies introduce the hidden curriculum of marginalized youth into the classroom, ensuring the presence and sustainability of the languages and cultures of these communities. Within this theoretical and pedagogical framework, both translanguaging and Hip-Hop Pedagogies challenge the traditional institutional norms that have historically viewed linguistically and culturally diverse students as deficient. Instead, they promote the utilization of students’ linguistic and cultural capital in the classroom. To this end, we designed and implemented a workshop for a linguistically and culturally diverse public school in Vitoria-Gasteiz in the Basque Autonomous Community. The workshop’s design was based on prior interventions that analyzed students’ multilingual identities through Hip-Hop Pedagogies. Specifically, our aim was to examine whether incorporating home languages by using translanguaging as a teaching approach, along with integrating content of interest to them, would enhance their self-conception. Results reveal that introducing a culturally sustaining approach in the classroom led to increased student engagement, manifested through more active participation in class discussions. The content introduced enabled them, moreover, to reconsider their multilingual identities and focus on topics of personal interest.
Wide angle wide band polarization insensitive metamaterial absorber for C, X and Ku band application with hexagonal packaging
Authors: Malviya Sunil , Ranjan Prakash , Barde Chetan 
Published: October 2024

Abstract
In this paper wide angle wide band polarization insensitive Metamaterial absorber (MA) has been proposed. The proposed unit cell structure consists of hexagonal concentric ring along with hexagonal packing. The structure is fabricated on FR4 substrate. The advantage of hexagonal packing is that it covers less area as compared to square packing. The unit cell structure is scaled w.r.t hexagonal ring and resistance of the substrate. The absorptivity achieved range from 6.54 to 14.85 GHz having Bandwidth (BW) of 8.31 GHz. The metamaterial behaviour of the structure is proven by plotting real and imaginary pat of permittivity and permeability. Absorption mechanism is shown by plotting surface current distribution at the top and bottom of the surface. The proposed MA structure is analysed for normal and oblique incidence. From the normal incidence it was found that structure has wide angle polarization insensitive. The absorptivity of the fabricated structure is measured inside the anechoic chamber. The simulated and measured plot is compared and found that both the results are very close to each other. At last, the proposed and already reported MAs are compared and from the observation it was found that proposed unit cell have larger BW compact in size, polarization insensitive and have hexagonal packing. The proposed MA covers partial C band, full X band and partial Ku band. The Proposed MA found practical applications for satellite communication, Wi-Fi devices, cordless telephone, military, air traffic control, defence tracking, vehicle speed detection.
On the demarcation of ecolinguistics
Authors: Steffensen Sune Vork 
Published: October 2024

Abstract
This article discusses the demarcation of contemporary ecolinguistics. It takes a starting point in different conceptualisations of the field, including (1) the claim that ecolinguistics is an umbrella term for work that attends to interconnections and dynamics in multiple contexts, (2) the claim that ecolinguistics comprises two traditions, a Haugenian tradition and a Hallidayan tradition, and (3) the claim that ecolinguistics consists of four strands that orient to the symbolic, sociocultural, natural, and cognitive ecology of language, respectively. Using bibliometric methods, the article concludes that there is currently no unity in ecolinguistics that warrants the first claim. Further, it concludes that there is no bibliometric or empirical evidence for the second claim, as there is virtually no connection between the two traditions, and hence they are two separate research areas, rather than two traditions within one field. Finally, it is shown that while there do indeed exist four ecological frameworks in linguistics, they are not subfields within ecolinguistics. It is concluded that contemporary ecolinguistics is defined by its preoccupation with natural ecologies. Based on this conclusion, it is suggested that the ecolinguistic preoccupation with natural ecologies presupposes treating language as integral to living and the ecology.
Ultrasound-guided transperineal vs transrectal prostate biopsy: A meta-analysis of diagnostic accuracy and complication rates
Authors: Wu Tao , Xing Yanchun 
Published: October 2024

Abstract

Objectives
We conducted a systematic review to compare the diagnostic utility of ultrasound-guided transperineal (TP) and transrectal (TR) prostate biopsy methods for prostate cancer detection.

Methods
We searched PubMed, Embase, Web of Science, and Cochrane databases up to October 30, 2023, for relevant studies, screening the literature and assessing bias independently.

Results
Eleven trials were analyzed using relative risk and 95% confidence intervals, with no evidence of publication bias. Diagnostic rates showed no significant difference between TP and TR biopsies (mean difference [MD]: 1.03, 95% confidence interval [CI]: 0.91–1.14, P = 0.56). Prostate volume analysis also showed no significant difference (MD: –0.07, 95% CI: –0.73 to 0.59, P < 0.0001, combined effect size P = 0.83). Similarly, PSA levels were comparable between TP and TR biopsies (MD: 0.93, 95% CI: –0.44 to 2.30, P < 0.0001, combined effect size P = 0.18).

Conclusion
Both biopsy methods exhibit similar diagnostic accuracy; however, TP has a lower risk of biopsy
The Early Upper Palaeolithic in Cueva del Arco (Murcia, Spain) and Its Contextualisation in the Iberian Mediterranean
Authors: Roman Dídac , Angelucci Diego , Armellini Jacopo , Carrión-Marco Yolanda , Carrión José S. , López Antonio , Sánchez-Martínez Noelia , Martínez-Varea Carmen , Nadal Jordi , Ochando Juan , Real Cristina , Sánchez-Hernández Alfredo , Martín-Lerma Ignacio 
Published: October 2024

Abstract
In this article, we present the results of the research carried out at the Gravettian occupation level of Cueva del Arco (Spain). For this purpose, a multidisciplinary investigation has been carried out in which all the elements recovered in the excavations carried out since 2015 at this site have been studied. The results are contextualised alongside all of the existing Gravettian sites in Mediterranean Iberia. The study of the material culture, the fauna, the landscape, and the dating has allowed us to approach the occupations of the site from many perspectives and has permitted us to conclude that Cueva del Arco was occupied sporadically at the beginning of the Gravettian period by a small human group in what would be the beginning of the consolidation of the anatomically modern humans (AMH) in this territory. Furthermore, these occupations were preceded by others belonging to the Aurignacian, which left hardly any remains in the cave. The data presented in this article lead us to believe that Cueva del Arco is a site of great importance for the knowledge of the beginning of the AMH settlement in the Iberian Mediterranean, both in its expansion towards the south and in its definitive consolidation in this territory.
Can different formulae be used in the diagnosis and staging of chronic kidney disease?
Authors: Çam Ergin , Kural Alev , Yılmaz Mürvet 
Published: October 2024

Abstract

Objectives
Chronic kidney disease (CKD), which has a significant prevalence of 15.7 % in Turkey, is a global health problem that particularly affects elderly. It is difficult to distinguish between age-related and CKD-related declines in kidney function with current glomerular filtration rate (GFR) estimation methods. The “HUGE” formula, incorporating haematocrit, urea, and gender, offers improved differentiation, targeting individuals over 40. This study aims to evaluate the effectiveness of the HUGE formula in estimating GFR in this demographic group and to establish a better diagnostic threshold.

Methods
A retrospective study of 500 participants over 40 years was conducted and divided into CKD (252) and non-CKD (248) based on demographics, laboratory tests and ultrasound evaluation. Renal function was classified by the HUGE equation (HUGE<0 for age-related decline; ≥ 0 for CKD) and GFR estimates were compared with KDIGO guidelines via CKD-EPI, FAS and BIS1.

Results
We observed significant discrepancies in estimated glomerular filtration rate (eGFR) and its staging among different formulas. The HUGE formula showed better agreement with eGFR staging after the cut-off point was set as “−1.58” and improved diagnostic accuracy, especially in stages 3a and 3b.

Conclusions
The study validates the HUGE formula improved accuracy in diagnosing CKD, especially for stages 3a and 3b, with a new cut-off value of “−1.58”. It supports the inclusion of the HUGE formula into current diagnostic practices to improve the identification and staging of CKD in individuals over the age of 40, while also demonstrating the necessity for further clinical evaluations.