bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of the Macroeconomical Variables on the Bankruptcy Rate of the Romanian Entities Working in the Agricultural Sector
Authors: Rodean (Cozma) Maria-Daciana , Baltes Nicolae 
Published: June 2016

Abstract
The study’s main objective is represented by the analysis of the reasons that lead to the appearance of an agricultural companies’ default risk, based on the failure rate model developed by Wilson. In the construction of the regression model were taken into consideration the evolution of the two macroeconomic variables: the inflation rate and the variation of the exchange rate over a period of 4 years (2010-2013). The research’ results have shown that the variation of the bankruptcy rate registered by the agricultural sector is 99.99% explained by the variation of both of the macroeconomic explanatory variables.
Method of Multiple Scales and Travelling Wave Solutions for (2+1)-Dimensional KdV Type Nonlinear Evolution Equations
Authors: Ayhan Burcu , Özer M. Naci , Bekir Ahmet 
Published: June 2016

Abstract
In this article, we applied the method of multiple scales for Korteweg–de Vries (KdV) type equations and we derived nonlinear Schrödinger (NLS) type equations. So we get a relation between KdV type equations and NLS type equations. In addition, exact solutions were found for KdV type equations. The

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-expansion methods were proposed to establish new exact solutions for KdV type differential equations. We obtained periodic and hyperbolic function solutions for these equations. These methods are very effective for getting travelling wave solutions of nonlinear evolution equations (NEEs).
Impact of age on pulmonary artery systolic pressures at rest and with exercise
Authors: Kane Garvan C. , Sachdev Arun , Villarraga Hector R. , Ammash Naser M. , Oh Jae K. , McGoon Michael D. , Pellikka Patricia A. , McCully Robert B. 
Published: June 2016

Abstract
Aim: It is not well known if advancing age influences normal rest or exercise pulmonary artery pressures. The purpose of the study was to evaluate the association of increasing age with measurements of pulmonary artery systolic pressure at rest and with exercise.
Subjects and methods: A total of 467 adults without cardiopulmonary disease and normal exercise capacity (age range: 18–85 years) underwent symptom-limited treadmill exercise testing with Doppler measurement of rest and exercise pulmonary artery systolic pressure.
Results: There was a progressive increase in rest and exercise pulmonary artery pressures with increasing age. Pulmonary artery systolic pressures at rest and with exercise were 25±5mmHg and 33±9mmHg, respectively, in those <40 years, and 30±5mmHg and 41±12mmHg, respectively, in those ≥70 years. While elevated left-sided cardiac filling pressures were excluded by protocol design, markers of arterial stiffness associated with the age-dependent effects on pulmonary pressures.
Conclusion: These data demonstrate that in echocardiographically normal adults, pulmonary artery systolic pressure increases with advancing age. This increase is seen at rest and with exercise. These increases in pulmonary pressure occur in association with decreasing transpulmonary flow and increases in systemic pulse pressure, suggesting that age-associated blood vessel stiffening may contribute to these differences in pulmonary artery systolic pressure.
El problema de la justicia: una respuesta al margen del liberalismo político
Authors: Gallo Gloria 
Published: June 2016

Jacques Derrida, siguiendo la ruta que ha señalado Walter Benjamin,se enfrenta a una discusión contra el Realismo y el liberalismo político,posturas que con el propósito de alcanzar un cierto grado de credibilidaden la discusión sobre la organización política de los hombres, hansustentado sus planteamientos en principios de hecho que, poco apoco fueron dejando de lado toda reflexión en torno al problema de lajusticia en términos aristotélicos. El sollen (deber-ser/deber-hacer) fueasí reemplazado por aquello que estipulara el Estado o por aquello que,las normas jurídicas determinaran. En este artículo presentaré la formaen que tanto el Realismo (de la mano de Hobbes y Schmitt) como elliberalismo han dado su versión sobre lo justo dentro de los límites delEstado y las normas jurídicas. Posteriormente, presentaré la deconstrucciónque hace Derrida de los conceptos clásicos de derecho y Estadoen relación a una justicia infinita, reflexión, que si bien no soluciona elproblema de los límites entre el derecho, el Estado y la justicia; si puededar luces sobre la necesidad de replantearnos una cierta concepción de justicia más allá del derecho y del Estado que nos señale un camino diferente frente a acontecimientosurgentes que están al orden del día.
Using Sequence Variants in Linkage Disequilibrium with Causative Mutations to Improve Across-Breed Prediction in Dairy Cattle: A Simulation Study
Authors: van den Berg Irene , Boichard Didier , Guldbrandtsen Bernt , Lund Mogens S 
Published: June 2016

Abstract
Sequence data are expected to increase the reliability of genomic prediction by containing causative mutations directly, especially in cases where low linkage disequilibrium between markers and causative mutations limits prediction reliability, such as across-breed prediction in dairy cattle. In practice, the causative mutations are unknown, and prediction with only variants in perfect linkage disequilibrium with the causative mutations is not realistic, leading to a reduced reliability compared to knowing the causative variants. Our objective was to use sequence data to investigate the potential benefits of sequence data for the prediction of genomic relationships, and consequently reliability of genomic breeding values. We used sequence data from five dairy cattle breeds, and a larger number of imputed sequences for two of the five breeds. We focused on the influence of linkage disequilibrium between markers and causative mutations, and assumed that a fraction of the causative mutations was shared across breeds and had the same effect across breeds. By comparing the loss in reliability of different scenarios, varying the distance between markers and causative mutations, using either all genome wide markers from commercial SNP chips, or only the markers closest to the causative mutations, we demonstrate the importance of using only variants very close to the causative mutations, especially for across-breed prediction. Rare variants improved prediction only if they were very close to rare causative mutations, and all causative mutations were rare. Our results show that sequence data can potentially improve genomic prediction, but careful selection of markers is essential.
A Meiotic Drive Element in the Maize PathogenFusarium verticillioidesIs Located Within a 102 kb Region of Chromosome V
Authors: Pyle Jay , Patel Tejas , Merrill Brianna , Nsokoshi Chabu , McCall Morgan , Proctor Robert H , Brown Daren W , Hammond Thomas M 
Published: June 2016

AbstractFusarium verticillioides is an agriculturally important fungus because of its association with maize and its propensity to contaminate grain with toxic compounds. Some isolates of the fungus harbor a meiotic drive element known as Spore killer (SkK) that causes nearly all surviving meiotic progeny from an SkK × Spore killer-susceptible (SkS) cross to inherit the SkK allele. SkK has been mapped to chromosome V but the genetic element responsible for meiotic drive has yet to be identified. In this study, we used cleaved amplified polymorphic sequence markers to genotype individual progeny from an SkK × SkS mapping population. We also sequenced the genomes of three progeny from the mapping population to determine their single nucleotide polymorphisms. These techniques allowed us to refine the location of SkK to a contiguous 102 kb interval of chromosome V, herein referred to as the Sk region. Relative to SkS genotypes, SkK genotypes have one extra gene within this region for a total of 42 genes. The additional gene in SkK genotypes, herein named SKC1 for Spore Killer Candidate 1, is the most highly expressed gene from the Sk region during early stages of sexual development. The Sk region also has three hyper-variable regions, the longest of which includes SKC1. The possibility that SKC1, or another gene from the Sk region, is an essential component of meiotic drive and spore killing is discussed.
Crosses Heterozygous for HybridNeurosporaTranslocation Strains Show Transmission Ratio Distortion Disfavoring Homokaryotic Ascospores Made Following Alternate Segregation
Authors: Giri Dev Ashish , Rekha Selvam , Kasbekar Durgadas P 
Published: June 2016

AbstractBy introgressing Neurospora crassa translocations into N. tetrasperma, we constructed heterokaryons bearing haploid nuclei of opposite mating types, and either the translocation and normal sequence chromosomes (i.e., [T + N]) or a duplication and its complementary deficiency (i.e., [Dp + Df]). The [T + N] heterokaryons result from alternate segregation of homologous centromeres, whereas adjacent-1 segregation generates [Dp + Df]. Self-cross of either heterokaryon produces [T + N] and [Dp + Df] progeny. Occasionally during N. tetrasperma ascus development, a pair of smaller homokaryotic ascospores replaces a heterokaryotic ascospore. Crosses with the Eight-spore mutant increase such replacement, and can generate asci with eight homokaryotic ascospores, either 4T + 4N from alternate segregation, or 4Dp + 4Df from adjacent-1 segregation. Crosses of some of the introgressed translocation strains with normal sequence N. tetrasperma produced more Dp than T or N homokaryotic progeny. We suggest this is due to an insufficiency for a presumptive ascospore maturation factor, which increases the chance that, in asci with &gt; 4 viable ascospores, none properly mature. Since only four viable ascospores (Dp or [Dp + Df]) share the limiting factor following adjacent-1 segregation, whereas four to eight ascospores compete for it following alternate segregation, this would explain why Dp homokaryons outnumber T and N types, whereas the heterokaryons are not as affected. We believe that this novel form of transmission ratio distortion is caused by a Bateson–Dobzhansky–Muller Incompatibility (BDMI) triggered by an N. crassa gene in the N. tetrasperma background. Heterokaryons tend not to out-cross, and crosses of Dp strains are barren, thus the BDMI impedes interspecies gene flow.
Phenotypes Associated with Second ChromosomePElement Insertions inDrosophila melanogaster
Authors: Kahsai Lily , Millburn Gillian H , Cook Kevin R 
Published: June 2016

AbstractIn Drosophila melanogaster, P element transposition has been a productive means of insertional mutagenesis. Thousands of genes have been tagged with natural and engineered P element constructs. Nevertheless, chromosomes carrying P element insertions tend to have high levels of background mutations from P elements inserting and excising during transposition. Consequently, the phenotypes seen when P element-bearing chromosomes are homozygous are often not attributable to the P insertions themselves. In this study, 178 strains in the Bloomington Drosophila Stock Center collection with P insertions on the second chromosome were complementation tested against molecularly defined chromosomal deletions and previously characterized single-gene mutations to determine if recessive lethality or sterility is associated with the P insertions rather than background mutations. This information should prove valuable to geneticists using these strains for experimental studies of gene function.
A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription
Authors: Sammons Morgan A , Zhu Jiajun , Berger Shelley L 
Published: June 2016

Abstract
The protein product of the Homo sapiens TP53 gene is a transcription factor (p53) that regulates the expression of genes critical for the response to DNA damage and tumor suppression, including genes involved in cell cycle arrest, apoptosis, DNA repair, metabolism, and a number of other tumorigenesis-related pathways. Differential transcriptional regulation of these genes is believed to alter the balance between two p53-dependent cell fates: cell cycle arrest or apoptosis. A number of previously identified p53 cofactors covalently modify and alter the function of both the p53 protein and histone proteins. Both gain- and loss-of-function mutations in chromatin modifiers have been strongly implicated in cancer development; thus, we sought to identify novel chromatin regulatory proteins that affect p53-dependent transcription and the balance between the expression of pro-cell cycle arrest and proapoptotic genes. We utilized an siRNA library designed against predicted chromatin regulatory proteins, and identified known and novel chromatin-related factors that affect both global p53-dependent transcription and gene-specific regulators of p53 transcriptional activation. The results from this screen will serve as a comprehensive resource for those interested in further characterizing chromatin and epigenetic factors that regulate p53 transcription.
RNAi Screen Identifies Novel Regulators of RNP Granules in theCaenorhabditis elegansGerm Line
Authors: Wood Megan P , Hollis Angela , Severance Ashley L , Karrick Megan L , Schisa Jennifer A 
Published: June 2016

AbstractComplexes of RNA and RNA binding proteins form large-scale supramolecular structures under many cellular contexts. In Caenorhabditis elegans, small germ granules are present in the germ line that share characteristics with liquid droplets that undergo phase transitions. In meiotically-arrested oocytes of middle-aged hermaphrodites, the germ granules appear to aggregate or condense into large assemblies of RNA-binding proteins and maternal mRNAs. Prior characterization of the assembly of large-scale RNP structures via candidate approaches has identified a small number of regulators of phase transitions in the C. elegans germ line; however, the assembly, function, and regulation of these large RNP assemblies remain incompletely understood. To identify genes that promote remodeling and assembly of large RNP granules in meiotically-arrested oocytes, we performed a targeted, functional RNAi screen and identified over 300 genes that regulate the assembly of the RNA-binding protein MEX-3 into large granules. Among the most common GO classes are several categories related to RNA biology, as well as novel categories such as cell cortex, ER, and chromosome segregation. We found that arrested oocytes that fail to localize MEX-3 into cortical granules display reduced oocyte quality, consistent with the idea that the larger RNP assemblies promote oocyte quality when fertilization is delayed. Interestingly, a relatively small number of genes overlap with the regulators of germ granule assembly during normal development, or with the regulators of solid RNP granules in cgh-1 oocytes, suggesting fundamental differences in the regulation of RNP granule phase transitions during meiotic arrest.
Including Psychology in Inclusive Pedagogy: Enriching the Dialogue?
Authors: Kershner Ruth 
Published: June 2016

Inclusive education is a complex field of study and practice that requires good communication and dialogue between all involved. Psychology has to some extent been marginalised in these educational dialogues. This is, in part, due to psychology’s perceived heritage in the standardised testing that has been used to support the educational segregation of certain individuals and groups of students. Some have also expressed fundamental doubts about the prospects of investigating human experience and education through ‘scientific’ method in psychology. In this paper I discuss the relationship between inclusive education, dialogue and psychology, with a focus on the dialogic aspects of inclusive classroom pedagogy. I analyse how a group of eight early career primary (elementary) school teachers in England talk about inclusive pedagogy at the start their involvement in a one-year research project on this topic. Their conversation suggests the strong presence of psychological thinking, alongside the teachers’ other references to classroom practice, children’s rights and social identities. Conclusions are drawn about the need to include the heterogeneous field of psychology in the continuing dialogues of inclusive education, while also considering new forms of psychology for inclusive education.
Evaluación del daño por carburización de un tubo retirado de servicio de un horno de pirólisis
Authors: Saavedra Rueda Jaqueline , Amézquita García Juan Carlos , Díaz Burgos Laura María , Laverde Cataño Dionisio , Bolívar Osorio Francisco Javier , Pérez Trujillo Francisco Javier 
Published: June 2016

La pirólisis de hidrocarburos es un proceso que se caracteriza por llevarse a cabo durante largos períodos de tiempo a temperaturas superiores a los 843° C y atmósferas altamente reductoras. Dichas condiciones severas contribuyen al deterioro por carburización de los serpentines de los hornos en donde ocurre el proceso de rotura térmica por pirólisis, de los hidrocarburos. En este trabajo, se evaluó el estado de daño de un tramo de serpentín de la zona radiante de un horno de pirólisis de etano para la producción de etileno. El tubo fue retirado del servicio del horno de pirólisis debido a la coquización presente en su interior. Posteriores análisis de Microscopia Electrónica de Barrido, análisis metalográfico, análisis de composición química, análisis de dureza y microdureza, permitieron evaluar el estado de daño por carburización.
Faktor-faktor Prognosis Kematian Tetanus Neonatorum di RS Kabupaten Indramayu dan Kabupaten Cirebon
Authors: Tantijati Lili , Bantas Krisnawati 
Published: June 2016

Angka Kematian Bayi (AKB) di Indonesia masih tetap tinggi. Berdasarkan Biro Pusat Statistik (BPS) pada tahun 1995 adalah 55/1000 kelahiran hidup. Salah satu penyebab utama dari kematian bayi adalah penyakit tetanus neonatorum . Tujuan dari penelitian ini adalah untuk menentukan hubungan antara usia saat ditemukan adanya indikasi penyakit neonatarum pada bayi dengan timbulnya kematian yang disebabkan oleh tetanus neonatorum pada bayi-bayi tersebut di Kabupaten Indramayu pada tahun 1996-2001 . Penelitian ini menggunakan disain studi epidemiologi kasus-kontrol dengan perbandingan kasus dan kontrol 1:1. Jumlah sampel, 160 penderita tetanus neonatorum. Populasi studi adalah penderita tetanus neonatorum yang dirawat di RSD kabupaten Cirebon dan kabupaten Indramayu tahun 1996 - 2001. Variabel-variabel yang diteliti adalah variabel kematian (sebagai variable terikat), dan variabel usia neonatus saat onset penyakit, status kekebalan neonatus, berat lahir neonatus, kecepatan pertolongan, jenis, dosis, dan cara pemberian antibiotika; jenis, dosis, dan cara pemberian obat anti kejang dan cara pemberian ATS (sebagai variabel bebas). Semua variabel yang diteliti diukur dengan skala kategorikal. Analisis yang dilakukan secara bertahap meliputi analisis univariat, bivariat dan multivariat. Analisis multivariat menggunakan analisis regresi logistik. Hasil penelitianmenunjukkan bahwa faktor-faktor prognosis kematian tetanus neonatorum adalah: usia penderita tetanus neonatorum ≤ 7 hari (OR= 20.06; nilai p= 0.000),dosis obat antibiotik yang lebih rendah dari standard (OR = 4.34; nilai p= 0.018), kecepatan pertolongan oleh fasilitas kesehatan >2 hari (OR=6.95; nilai p=0.000).Kata kunci: Faktor prognosis, kematian tetanus neonatorum.AbstractThe Infant Mortality Rate (IMR) in Indonesia is still high. Based on Central Bureau of Statistics (CBS) data, the IMR in 1995 was 55/1000 live births. One of the main causes of infant death in Indonesia is tetanus neonatorum. The objective of this study was to determine the relationship between neonates’ age of disease onset and the infant death caused by tetanus neonatorum in Indramayu and Cirebon Districts in 1996-2001. The study design was case-control study with ratio of the number of cases and control of 1:1. The total number of sample was 160 neonates with tetanus neonatorum, consisted of 80-cases(death) and 80-control (live). The study population was neonates with tetanus neonatorum who were hospitalized in Cirebon and IndramayuDistrict Hospital. All of the study variables were measured using categorical scale. Study was analyzed by multivariate analysis, using unconditional logistic regression method. The result of the study showed that the prognostic factors of tetanus neonatorum death risk were age < 7 days old (OR =20.06 ; p value=0.000), neonates with lower than standard dose of antibiotics (OR=4.34; p value=0.018); delay of help by health facilities > 2 days (OR=6.95; p value=0.000).Key words: Prognosis factor, tetanus neonatorun death.
Prevalensi dan Determinan Hipertensi di Pulau Jawa, Tahun 2004
Authors: Setiawan Zamhir 
Published: June 2016

Hipertensi merupakan faktor risiko utama kardiovaskuler yang merupakan penyebab utama kematian di seluruh dunia. Peningkatan umur harapan hidup dan perubahan gaya hidup meningkatkan faktor risiko hipertensi di berbagai negara. Tujuan penelitian ini (1) Mengetahui prevalensi hipertensi dan penyebarannya di Pulau Jawa tahun 2004. (2) Mengetahui faktor-faktor sosiodemografi yang berhubungan dengan kejadian hipertensi. (3) Mengetahui kontribusi dan dampak potensial masing-masing faktor tersebut. Penelitian dengan rancangan studi Ekologi Multilevel ini menggabungkan variabel tingkat pengukuran individu dengan tingkat pengukuran ekologi dalam analisis bersama, dengan unit analisis individu. Analisis kontekstual dilakukan melalui kerangka konsep hipertensi, menggunakan metode analisis regresi logistik ganda, dengan status hipertensi sebagai variabel dependen. Data variabel dependen dan variabel perancu yang merupakan data pengukuran tingkat individu diambil dari data SKRT 2004. Data sosiodemografi tingkat pengukuran ekologi sebagai variabel independen utama, diperoleh dari Profil Kesehatan Indonesia, Statistik Indonesia, Statistik Kesehatan, Statistik Kesejahteraan Rakyat, danData Departemen Dalam Negeri, unit pengamatan provinsi. Hasil penelitian ini menunjukkan prevalensi hipertensi di Pulau Jawa 41,9%, dengan kisaran di masing-masing provinsi 36,6%-47,7%. Prevalensi di perkotaan 39,9% (37,0%-45,8%) dan di perdesaan 44,1% (36,2%-51,7%). Kata kunci: Hipertensi, faktor sosiodemografiAbstractHypertension is a main risk factor of cardiovascular disease which is ranked as number one cause of death in the world. The increase of life expectancy and changes in life style have increased the prevalence of hypertension risk factor in both developed and developing countries. The objectives of this study are (1) To know the prevalence and distribution of hypertension in di Java island, in year 2004. (2) To know sosiodemographic factors related to hypertension. (3) To know the contribution of each sosiodemographic factor toward hypertension. The study used multilevel ecologic study design that integrated both individual and ecological level variables measurement. The analysis method used in this study was contextual analysis and multiple logistic regression with hypertension status as dependent variable. The individual level measurement of variables such as hypertension status and age, job, education and sex is taken from Household Health Survey (SKRT) 2004. The sosiodemographic data which was ecological measurement level served as the main independent variables were taken from Indonesian Health Profile, Indonesian Health Statistics, Public Welfare Statistics and data from Department of Internal Affair, particularly from Province Surveillance Unit. The study results showed that the prevalence of hypertension in Java Island was 41.9%, with range of prevalence in provincial level of 36.6%-47.7%. The prevalence in urban areas was 39.9% (37.0%-45.8%) and in rural areas was 44.1% (36.2%-51.7%)Keywords: Hypertension, sosiodemographic factors