bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hungry Porphyrins: Protonation and Self‐Metalation of Tetraphenylporphyrin on TiO2(110) ‐ 1 × 1
Authors: Köbl Julia , Wang Tao , Wang Cici , Drost Martin , Tu Fan , Xu Qian , Ju Huanxin , Wechsler Daniel , Franke Matthias , Pan Haibin , Marbach Hubertus , Steinrück Hans‐Peter , Zhu Junfa , Lytken Ole 
Published: November 2016

AbstractWe have studied the adsorption and self‐metalation of tetraphenylporphyrin (2HTPP) on TiO2(110) ‐ 1 × 1 with X‐ray Photoelectron Spectroscopy (XPS) and Scanning Tunneling Microscopy (STM). Upon adsorption at room temperature the first monolayer of 2HTPP is protonated by protons from the surface, forming porphyrin diacid (4HTPP2+). In STM, single molecules with low mobility and no long‐range order were observed. As the surface is heated to 400 K, any unprotonated 2HTPP molecules in the second layer metalate, forming titanyl tetraphenylporphyrin (TiOTPP), but the protonated molecules in the first layer remain. As the surface is heated further to 550 K even the protonated 4HTPP2+ molecules metalate and only TiOTPP remain on the surface.
Microwave‐Assisted Synthesis of Highly Monodispersed Single‐Walled Alunminosilicate Nanotubes
Authors: Lam Chon Hei , Yang An‐Chih , Chi Heng‐Yu , Chan Kuan‐Ying , Hsieh Chih‐Chen , Kang Dun‐Yen 
Published: November 2016

AbstractThe synthesis of single‐walled aluminosilicate nanotubes (AlSiNTs) generally requires conductive heating over a period of 4 days. This paper outlines a novel microwave‐assisted method for the synthesis of AlSiNTs, which achieves yields on par with conventional methods in just 12 hours. The AlSiNTs obtained using the proposed method are much shorter (average length of 140 nm) than those synthesized in a reactor subjected to conductive heating in an oil bath (average length of 480 nm). The proposed synthesis method produces a product with highly monodispersed length distribution (100 – 200 nm), compared to those obtained from a conductively‐heated reactor (50 – 950 nm). We applied suspensions of the resulting AlSiNTs to produce thin films via spin coating. The thin films cast from microwaved AlSiNTs yielded a far smoother top surface with uniform surface morphology. This can be attributed to the shorter average length and the narrower length distribution of the AlSiNTs in the casting solution.
Development of a 18F‐labeled Diaryl‐Substituted Dihydropyrrolo[3,2,1‐hi]indole as Potential Probe for Functional Imaging of Cyclooxygenase‐2 with PET
Authors: Gassner Cemena , Neuber Christin , Laube Markus , Bergmann Ralf , Kniess Torsten , Pietzsch Jens 
Published: November 2016

AbstractHigh COX‐2 expression is associated with tumor progression and poor treatment response. Imaging of functional COX‐2 expression by PET would provide beneficial information for theranostics. Here we describe precursor synthesis and radiolabeling attempts of (dihydro)pyrrolo[3,2,1‐hi]indoles [18F]DHPI and [18F]PI, two novel tricyclic COX‐2 inhibitors. Contrary to [18F]PI, [18F]DHPI was accessible by [18F]fluorination under mild basic conditions and McMurry cyclization. Radiopharmacological evaluation was performed in vitro by investigating cellular uptake in human COX‐2‐positive cells, and in vivo in rats and A2058‐melanoma xenograft mice, by focusing on metabolic stability and tumor uptake. To assess COX‐2 specificity, blocking experiments with celecoxib were performed. Despite of high COX‐2 selectivity and metabolic stability, [18F]DHPI did not show COX‐2‐dependent cell and tissue uptake, in part explained by high unspecific binding. Since appropriate lipophilicity is a prerequisite for targeting intracellularly localized COX‐2, future efforts should focus on use of longer‐lived radionuclides and/or targeted delivery systems.
Exegesis of the Introduction and Sect. I from “Fundamentals of the Mechanics of Continua”** by E. Hellinger
Authors: Eugster Simon R. , dell'Isola Francesco 
Published: November 2016

The fundamental review article DIE ALLGEMEINEN ANSÄTZE DER MECHANIK DER KONTINUA in the Encyklopädie der mathematischen Wissenschaften mit Einschluss ihrer Anwendungen, Bd. IV‐4, Hft. 5 (1913) by Ernst Hellinger has not been translated into English so far. We believe that such a circumstance is really deprecative, as the insight reached by Hellinger in the mathematical structure of continuum mechanics seems, in some aspects, unsurpassed even nowadays. Hellinger's scientific manuscripts do not fill more than one and half boxes in library storage , but their impact on mathematics and mechanical sciences is profound. Indeed, the Hellinger‐Reissner variational principle is still a fundamental tool in theoretical and numerical mechanics. The intent of this paper is threefold: i) to allow to those who cannot understand German to enjoy the reading of a crystal‐clear and still topical article whose content has some enlightening parts, ii) to show that only one century ago the principle of virtual work (or virtual velocities) was regarded as the central principle in continuum mechanics and that Hellinger did forecast already then the main lines of its development, iii) to discuss some technical and conceptual aspects of the variational principles in continuum mechanics which some authors consider still controversial.
A novel mechanism of immunity controls the onset of cinnamycin biosynthesis in Streptomyces cinnamoneus DSM 40646
Authors: O’Rourke Sean , Widdick David , Bibb Mervyn 
Published: November 2016

Abstract
Streptomyces cinnamoneus DSM 40646 produces the Class II lantibiotic cinnamycin which possesses an unusual mechanism of action, binding to the membrane lipid phosphatidylethanolamine (PE) to elicit its antimicrobial activity. A comprehensive analysis of the cinnamycin biosynthetic gene cluster has unveiled a novel mechanism of immunity in which the producing organism methylates its entire complement of PE prior to the onset of cinnamycin production. Deletion of the PE methyl transferase gene cinorf10, or the two-component regulatory system (cinKR) that controls its expression, leads not only to sensitivity to the closely related lantibiotic duramycin, but also abolishes cinnamycin production, presumably reflecting a fail-safe mechanism that serves to ensure that biosynthesis does not occur until immunity has been established.
Retracted: Novel Nonionic Polyurethane Surfactants and Ag Nanohybrids: Influence of Nonionic Polymeric Chains
Authors: Negm Nabel A. , El Hashash Maher A. , Youssif Mona A. , Ismail Eid A. , Abdeen Zizi I. , Rahman Nasser R. Abdel 
Published: November 2016

AbstractFive novel nonionic surfactants were prepared by the reaction of polyethylene glycol of different molecular weights with toluene diisocyanate. The obtained polyurethane polymers were reacted with oleic acid to obtain the nonionic polyurethane surfactants. The structures of the synthesized compounds were determined by using: Fourier Transform Infrared Spectroscopy (FTIR) and their average molecular weights by means of GC analysis. Silver nanohybrids of the nonionic polyurethane surfactants were prepared via physical combination by chemically prepared silver nanoparticles. The silver nanohybrids were determined using: UV, TEM, and DLS spectroscopy. The influence of the nonionic chain length (polyethylene glycol chains) on the surface activity of the synthesized nonionic polyurethane oleate surface active agents and their silver nanohybrids was studied. The results of surface activity of the nonionic polyurethanes oleate and their nanohybrids showed an increase in the critical micelle concentration by decreasing the polyethylene glycol chain lengths. The nanohybrids were also more surface active. Longer polyethylene glycol chains provide good protection for the formed silver nanoparticles than the shorter chains.
An adaptive randomized trial of dialectical behavior therapy and cognitive behavior therapy for binge-eating
Authors: Chen E. Y. , Cacioppo J. , Fettich K. , Gallop R. , McCloskey M. S. , Olino T. , Zeffiro T. A. 
Published: November 2016

BackgroundEarly weak treatment response is one of the few trans-diagnostic, treatment-agnostic predictors of poor outcome following a full treatment course. We sought to improve the outcome of clients with weak initial response to guided self-help cognitive behavior therapy (GSH).MethodOne hundred and nine women with binge-eating disorder (BED) or bulimia nervosa (BN) (DSM-IV-TR) received 4 weeks of GSH. Based on their response, they were grouped into: (1) early strong responders who continued GSH (cGSH), and early weak responders randomized to (2) dialectical behavior therapy (DBT), or (3) individual and additional group cognitive behavior therapy (CBT+).ResultsBaseline objective binge-eating-day (OBD) frequency was similar between DBT, CBT+ and cGSH. During treatment, OBD frequency reduction was significantly slower in DBT and CBT+ relative to cGSH. Relative to cGSH, OBD frequency was significantly greater at the end of DBT (d = 0.27) and CBT+ (d = 0.31) although these effects were small and within-treatment effects from baseline were large (d = 1.41, 0.95, 1.11, respectively). OBD improvements significantly diminished in all groups during 12 months follow-up but were significantly better sustained in DBT relative to cGSH (d = −0.43). At 6- and 12-month follow-up assessments, DBT, CBT and cGSH did not differ in OBD.ConclusionsEarly weak response to GSH may be overcome by additional intensive treatment. Evidence was insufficient to support superiority of either DBT or CBT+ for early weak responders relative to early strong responders in cGSH; both were helpful. Future studies using adaptive designs are needed to assess the use of early response to efficiently deliver care to large heterogeneous client groups.
Pension Insecurity and Wellbeing in Europe
Authors: OLIVERA JAVIER , PONOMARENKO VALENTINA 
Published: November 2016

AbstractThis paper studies pension insecurity in a sample of non-retired individuals aged 50 years or older from 18 European countries. We capture pension insecurity with the subjective expectations on the probability that the government will reduce the pensions of the individual before retirement or will increase the statutory retirement age. We argue that changes in economic conditions and policy affect the formation of such probabilities, and through this, subjective wellbeing. In particular, we study the effects of pension insecurity on subjective wellbeing with pooled linear models, regressions per quintiles and instrumental variables. We find a statistically significant, stable and negative association between pension insecurity and subjective wellbeing. Our findings reveal that the individuals who are more affected by pension insecurity are those who are further away from their retirement, have lower income, assess their life survival as low, have higher cognitive abilities and do not expect private pension payments.
The impact of measures taken in the outdoor environment on an ageing population: a panel study over a ten-year period
Authors: HALLGRIMSDOTTIR BERGLIND , STÅHL AGNETA 
Published: November 2016

ABSTRACTFor older people mobility and participation in activities can be restricted both by individual factors and by the environment. The aim of this paper was to examine the longitudinal impact of measures taken in the outdoor environment on an ageing population. The following factors were examined on three occasions over a nine-year period: frequency of walking; differences in report on environmental barriers; and reported valuation of the outdoor environment; and how these relate to different characteristics. At the second follow-up, the respondents experienced more functional limitations and more were using mobility devices than at baseline. At the first and second follow-up, the respondents did not experience as many environmental barriers in their outdoor environment compared to baseline. However, frequency of walking and evaluation of the outdoor environment decreased in general between baseline and first- and second follow-up. A quite promising result from the study is that compared to people not using mobility devices, mobility device users were more likely to be frequent walkers at first- and second follow-up than at baseline. Likewise, at second follow-up respondents having functional limitations were less likely to experience traffic barriers than at baseline. In terms of accessibility, usability and mobility for an ageing population, the results are promising, showing that measures in the outdoor environment can possibly facilitate walking for those who are more fragile, even in a longitudinal perspective.
Hebrew verbal passives in Later Language Development: the interface of register and verb morphology
Authors: RAVID DORIT , VERED LIZZY 
Published: November 2016

AbstractThe current study examined the production of Hebrew verbal passives across adolescence as mediated by linguistic register and verb morphology. Participants aged eight to sixteen years and a group of adults were asked to change written active-voice sentences into corresponding passive-voice forms, divided by verb register (neutral and high),binyanpattern (Qal / Nif'al, Hif'il / Huf'al, andPi'el / Pu'al), and verb tense (past and future tense). Results showed that Hebrew passive morphology is a very late acquisition, almost a decade later than in other languages, that passivizing neutral-register verbs was less challenging than high-register verbs, and that past tense verbs were easier to passivize than future tense verbs. An order of acquisition was determined among the threebinyanpairs. The paper provides an account of these findings grounded in the event-telling role of Hebrew passives in discourse and the spurt of abstract, lexically specific vocabulary in Later Language Development.
Gendering Guilt among Dependent Family Members’ Caregivers
Authors: Brea Maria-Teresa , Albar María-Jesús , Casado-Mejia Rosa 
Published: November 2016

AbstractThis study analyzes guilt among family caregivers of dependent patients, from a gender perspective. A qualitative design was used, conducting in-depth interviews and focus groups. Using purposive sampling, we selected 73 family caregivers and 23 health professionals (family medicine, community nursing, and social work) from the Primary Care District of Seville. The content of the information collected was analyzed in terms of the following categories: a) guilt for abandoning family and friends; b) guilt for the relationship with the dependent person; and c) guilt for placing the relative in a nursing home. To validate the findings, data sources, methodological techniques, and researchers’ disciplines were all triangulated. Results indicated that women report more guilt than men for abandoning family and friends, and because of their relationship with the dependent person. However, with respect to nursing home placement, no difference was observed as a function of gender. The high incidence of caregiver guilt needs to be addressed by health professionals to avoid the emergence of other mental health issues.
A hyperaccumulation pathway to three-dimensional hierarchical porous nanocomposites for highly robust high-power electrodes
Authors: Zhu Jian , Shan Yu , Wang Tao , Sun Hongtao , Zhao Zipeng , Mei Lin , Fan Zheng , Xu Zhi , Shakir Imran , Huang Yu , Lu Bingan , Duan Xiangfeng 
Published: November 2016

AbstractNatural plants consist of a hierarchical architecture featuring an intricate network of highly interconnected struts and channels that not only ensure extraordinary structural stability, but also allow efficient transport of nutrients and electrolytes throughout the entire plants. Here we show that a hyperaccumulation effect can allow efficient enrichment of selected metal ions (for example, Sn2+, Mn2+) in the halophytic plants, which can then be converted into three-dimensional carbon/metal oxide (3DC/MOx) nanocomposites with both the composition and structure hierarchy. The nanocomposites retain the 3D hierarchical porous network structure, with ultrafine MOx nanoparticles uniformly distributed in multi-layers of carbon derived from the cell wall, cytomembrane and tonoplast. It can simultaneously ensure efficient electron and ion transport and help withstand the mechanical stress during the repeated electrochemical cycles, enabling the active material to combine high specific capacities typical of batteries and the cycling stability of supercapacitors.
‘To use or not to use’: a qualitative study to evaluate experiences of healthcare providers and patients with the assessment of burden of COPD (ABC) tool
Authors: Slok Annerika H M , Twellaar Mascha , Jutbo Leslie , Kotz Daniel , Chavannes Niels H , Holverda Sebastiaan , Salomé Philippe L , Dekhuijzen P N Richard , Rutten-van Mölken Maureen P M H , Schuiten Denise , in ’t Veen Johannes C C M , van Schayck Onno C P 
Published: November 2016

AbstractIn the management of chronic conditions, such as chronic obstructive pulmonary disease (COPD), there is a shift from doctor-driven care to patient-centred integrated care with active involvement of and self-management by the patient. A recently developed tool, the assessment of burden of COPD (ABC) tool, can be used in this transition to facilitate self-management support and shared decision-making. We performed a qualitative study, in which we collected and analysed the data using the methods of conventional content analyses. We performed in-depth interviews consisting of mainly open questions. Fifteen healthcare providers and 21 patients were interviewed who had worked with the ABC tool in daily care. In general, participants responded positively to the tool. Healthcare providers felt the visual representation provided was effective and comprehensible for patients and provided them with insight into their disease, a finding that patients confirmed. If patients were allowed to choose between a consultation with or without the ABC tool, the majority would prefer using the tool: it provides them with an overview and insight, which makes it easier to discuss all relevant topics related to COPD. The tool can provide structure in consultations, and is compatible with the concepts of ‘motivational interviewing’ and ‘individualised care-planning’. Suggestions for improvement related to content and layout. So far, the tool has only been available as a stand-alone online program, that is not connected to the electronic medical record systems. It was therefore suggested that the tool be integrated into the systems to enhance its usability and its uptake by healthcare providers.
Thermal gradient induced tweezers for the manipulation of particles and cells
Authors: Chen Jiajie , Cong Hengji , Loo Jacky , Kang Zhiwen , Tang Minghui , Zhang Haixi , Wu Shu-Yuen , Kong Siu-Kai , Ho Ho-Pui 
Published: November 2016

AbstractOptical tweezers are a well-established tool for manipulating small objects. However, their integration with microfluidic devices often requires an objective lens. More importantly, trapping of non-transparent or optically sensitive targets is particularly challenging for optical tweezers. Here, for the first time, we present a photon-free trapping technique based on electro-thermally induced forces. We demonstrate that thermal-gradient-induced thermophoresis and thermal convection can lead to trapping of polystyrene spheres and live cells. While the subject of thermophoresis, particularly in the micro- and nano-scale, still remains to be fully explored, our experimental results have provided a reasonable explanation for the trapping effect. The so-called thermal tweezers, which can be readily fabricated by femtosecond laser writing, operate with low input power density and are highly versatile in terms of device configuration, thus rendering high potential for integration with microfluidic devices as well as lab-on-a-chip systems.
Antagonizing STAT5B dimerization with an osmium complex
Authors: Liu Li-Juan , Wang Wanhe , Kang Tian-Shu , Liang Jia-Xin , Liu Chenfu , Kwong Daniel W. J. , Wong Vincent Kam Wai , Ma Dik-Lung , Leung Chung-Hang 
Published: November 2016

AbstractTargeting STAT5 is an appealing therapeutic strategy for the treatment of hematologic malignancies and inflammation. Here, we present the novel osmium(II) complex 1 as the first metal-based inhibitor of STAT5B dimerization. Complex 1 exhibited superior inhibitory activity against STAT5B DNA binding compared to STAT5A DNA binding. Moreover, 1 repressed STAT5B transcription and blocked STAT5B dimerization via binding to the STAT5B protein, thereby inhibiting STAT5B translocation to the nucleus. Furthermore, 1 was able to selectively inhibit STAT5B phosphorylation without affecting the expression level of STAT5B.
Temporal dynamics, population characterization and mycotoxins accumulation of Fusarium graminearum in Eastern China
Authors: Qiu Jian-bo , Sun Jing-Tao , Yu Ming-Zheng , Xu Jian-Hong , Shi Jian-Rong 
Published: November 2016

AbstractTrichothecene genotype composition, mycotoxin production, genetic diversity, and population structure were analyzed, using 185 Fusarium strains collected from wheat (Triticum aestivum L.) throughout the Jiangsu province during 1976, 1983, 1998, 2006, and 2014. The results showed that 3-acetyldeoxynivalenol (3ADON) was consistently the predominant type in this region over 40 years, and the nivalenol (NIV) type has emerged since 1998. Long-term rotation of wheat and rice (Oryza sativa L.), rather than fungicide application, crop fitness, or weather conditions, might be the main cause of this phenomenon. The genetic diversity results from two toxin synthetic genes, Pks4 and Tri10, and variable number of tandem repeat (VNTR) markers revealed the largest variance within the population in 1998, which was also the year with the highest production of mycotoxins. Population differentiation analysis indicated that major temporal population comparisons from the same area were not significantly differentiated. Our results showed that dominant species could maintain genetic stability for a long time, and Pks4 would be of utility in genetic and population studies.
Nanocolumnar Crystalline Vanadium Oxide-Molybdenum Oxide Antireflective Smart Thin Films with Superior Nanomechanical Properties
Authors: Dey Arjun , Nayak Manish Kumar , Esther A. Carmel Mary , Pradeepkumar Maurya Sandeep , Porwal Deeksha , Gupta A. K. , Bera Parthasarathi , Barshilia Harish C. , Mukhopadhyay Anoop Kumar , Pandey Ajoy Kumar , Khan Kallol , Bhattacharya Manjima , Kumar D. Raghavendra , Sridhara N. , Sharma Anand Kumar 
Published: November 2016

AbstractVanadium oxide-molybdenum oxide (VO-MO) thin (21–475 nm) films were grown on quartz and silicon substrates by pulsed RF magnetron sputtering technique by altering the RF power from 100 to 600 W. Crystalline VO-MO thin films showed the mixed phases of vanadium oxides e.g., V2O5, V2O3 and VO2 along with MoO3. Reversible or smart transition was found to occur just above the room temperature i.e., at ~45–50 °C. The VO-MO films deposited on quartz showed a gradual decrease in transmittance with increase in film thickness. But, the VO-MO films on silicon exhibited reflectance that was significantly lower than that of the substrate. Further, the effect of low temperature (i.e., 100 °C) vacuum (10−5 mbar) annealing on optical properties e.g., solar absorptance, transmittance and reflectance as well as the optical constants e.g., optical band gap, refractive index and extinction coefficient were studied. Sheet resistance, oxidation state and nanomechanical properties e.g., nanohardness and elastic modulus of the VO-MO thin films were also investigated in as-deposited condition as well as after the vacuum annealing treatment. Finally, the combination of the nanoindentation technique and the finite element modeling (FEM) was employed to investigate yield stress and von Mises stress distribution of the VO-MO thin films.