bluuebunny/crossref_metadata_2025_split huggingface dataset:
Groundwater similarity across a watershed derived from time‐warped and flow‐corrected time series
Authors: Rinderer M. , McGlynn B. L. , van Meerveld H. J. 
Published: March 2017

AbstractInformation about catchment‐scale groundwater dynamics is necessary to understand how catchments store and release water and why water quantity and quality varies in streams. However, groundwater level monitoring is often restricted to a limited number of sites. Knowledge of the factors that determine similarity between monitoring sites can be used to predict catchment‐scale groundwater storage and connectivity of different runoff source areas. We used distance‐based and correlation‐based similarity measures to quantify the spatial and temporal differences in shallow groundwater similarity for 51 monitoring sites in a Swiss prealpine catchment. The 41 months long time series were preprocessed using Dynamic Time‐Warping and a Flow‐corrected Time Transformation to account for small timing differences and bias toward low‐flow periods. The mean distance‐based groundwater similarity was correlated to topographic indices, such as upslope contributing area, topographic wetness index, and local slope. Correlation‐based similarity was less related to landscape position but instead revealed differences between seasons. Analysis of variance and partial Mantel tests showed that landscape position, represented by the topographic wetness index, explained 52% of the variability in mean distance‐based groundwater similarity, while spatial distance, represented by the Euclidean distance, explained only 5%. The variability in distance‐based similarity and correlation‐based similarity between groundwater and streamflow time series was significantly larger for midslope locations than for other landscape positions. This suggests that groundwater dynamics at these midslope sites, which are important to understand runoff source areas and hydrological connectivity at the catchment scale, are most difficult to predict.
An improved constant evaporative fraction method for estimating daily evapotranspiration from remotely sensed instantaneous observations
Authors: Tang Ronglin , Li Zhao‐Liang 
Published: March 2017

AbstractEvapotranspiration (ET) is a primary mechanism for water and heat transfer between land and the atmosphere. One approach to estimate ET is from instantaneous remotely sensed data. The constant evaporative fraction (EF) method is then usually used to estimate integrated daily fluxes, which are typically underestimated values. Here we present a theoretical improvement to the conventional EF. The improved EF is shown to be robust and superior to the conventional approach, and it significantly reduces the underestimation bias.
Ultra‐relativistic radiation belt extinction and ULF wave radial diffusion: Modeling the September 2014 extended dropout event
Authors: Ozeke Louis G. , Mann Ian R. , Murphy Kyle R. , Sibeck David G. , Baker Daniel N. 
Published: March 2017

AbstractIn September 2014 an unusually long‐lasting (≳10 days) ultra‐relativistic electron flux depletion occurred in the outer radiation belt despite ongoing solar wind forcing. We simulate this period using a ULF wave radial diffusion model, driven by observed ULF wave power coupled to flux variations at the outer boundary at L* = 5, including empirical electron loss models due to chorus and hiss wave scattering. Our results show that unexplained rapid main phase loss, that depletes the belt within hours, is essential to explain the observations. Such ultra‐relativistic electron extinction decouples the prestorm and poststorm fluxes, revealing the subsequent belt dynamics to be surprisingly independent of prestorm flux. However, once this extinction is included, ULF wave transport and coupling to the outer boundary explain the extended depletion event and also the eventual flux recovery. Neither local acceleration nor ongoing losses from hiss or chorus wave scattering to the atmosphere are required.
Myeloid neoplasms with concurrent BCR‐ABL1 and CBFB rearrangements: A series of 10 cases of a clinically aggressive neoplasm
Authors: Salem Alireza , Loghavi Sanam , Tang Guilin , Huh Yang O. , Jabbour Elias J. , Kantarjian Hagop , Wang Wei , Hu Shimin , Luthra Rajyalakshmi , Medeiros L. Jeffrey , Khoury Joseph D. 
Published: March 2017

AbstractChronic myeloid leukemia (CML) is defined by the presence of t(9;22)(q34;q11.2)/BCR‐ABL1. Additional chromosomal abnormalities confer an adverse prognosis and are particularly common in the blast phase of CML (CML‐BP). CBFB rearrangement, particularly CBFB‐MYH11 fusion resulting from inv(16)(p13.1q22) or t(16;16)(p13.1;q22), is an acute myeloid leukemia (AML)‐defining alteration that is associated with a favorable outcome. The co‐occurrence of BCR‐ABL1 and CBFB rearrangement is extremely rare, and the significance of this finding remains unclear. We identified 10 patients with myeloid neoplasms harboring BCR‐ABL1 and CBFB rearrangement. The study group included six men and four women with a median age of 51 years (range, 20‐71 years). The sequence of molecular alterations could be determined in nine cases: BCR‐ABL1 preceded CBFB rearrangement in seven, CBFB rearrangement preceded BCR‐ABL1 in one, and both alterations were discovered simultaneously in one patient. BCR‐ABL1 encoded for p210 kD in all cases in which BCR‐ABL1 preceded CBFB rearrangement; a p190 kD was identified in the other three cases. Two patients were treated with the FLAG‐IDA regimen (fludarabine, cytarabine, idarubicin, and G‐CSF) and tyrosine kinase inhibitors (TKI); seven with other cytarabine‐based regimens and TKIs, and one with ponatinib alone. At last follow up (median, 16 months; range 2‐85), 7 of 10 patients had died. The co‐existence of BCR‐ABL1 and CBFB rearrangement is associated with poor outcome and a clinical course similar to that of CML‐BP, and unlike de novo AML with CBFB rearrangement, suggesting that high‐intensity chemotherapy with TKI should be considered in these patients.
Stroke in right dorsal anterior insular cortex Is related to myocardial injury
Authors: Krause Thomas , Werner Kathrin , Fiebach Jochen B. , Villringer Kersten , Piper Sophie K. , Haeusler Karl Georg , Endres Matthias , Scheitz Jan F. , Nolte Christian H. 
Published: March 2017

ObjectiveElevated levels of cardiac troponin, and especially their relative changes over time, indicate acute myocardial injury. They are also frequently observed after acute ischemic stroke (AIS), indicating poor functional outcome and increased mortality. However, recent evidence showed that, in most AIS patients, myocardial injury is not caused by coronary ischemia. Instead, stroke lesion location has been suggested to precipitate myocardial injury.MethodsVoxel‐based lesion‐symptom mapping (VLSM) was used in 299 patients who had a magnetic resonance imaging–confirmed acute ischemic stroke within the anterior circulation and a high‐sensitivity cardiac troponin T (hs‐cTnT) acquired on the day of admission. Of these, 228 had a second troponin measurement during the acute phase. The absolute hs‐cTnT levels above the 99th percentile of a healthy reference population (≥14ng/l) as well as their relative temporal changes were used as continuous variables of interest in the VLSM model, including a multiple regression analysis adjusted for confounding variables.ResultsThe anterior insular cortex of the right hemisphere, in particular its dorsal subregion, was significantly associated with the relative temporal changes of hs‐cTnT (p < 0.01, corrected for multiple comparisons). In contrast, the baseline hs‐cTnT levels on admission were not related to lesion location anywhere within the anterior circulation.InterpretationOur results amplify recent evidence from functional neuroimaging, which suggests a prominent role of dorsal anterior insular cortex in the parasympathetic control of cardiac and autonomic function. Acute vascular damage of this insular subregion might lead to autonomic dysbalance and an upregulation of sympathetic function, thereby resulting in myocardial injury. Ann Neurol 2017;81:502–511
Olig1 is required for noggin‐induced neonatal myelin repair
Authors: Sabo Jennifer K. , Heine Vivi , Silbereis John C. , Schirmer Lucas , Levison Steven W. , Rowitch David H. 
Published: March 2017

ObjectiveNeonatal white matter injury (NWMI) is a lesion found in preterm infants that can lead to cerebral palsy. Although antagonists of bone morphogenetic protein (BMP) signaling, such as Noggin, promote oligodendrocyte precursor cell (OPC) production after hypoxic‐ischemic (HI) injury, the downstream functional targets are poorly understood. The basic helix‐loop‐helix protein, oligodendrocyte transcription factor 1 (Olig1), promotes oligodendrocyte (OL) development and is essential during remyelination in adult mice. Here, we investigated whether Olig1 function is required downstream of BMP antagonism for response to injury in the neonatal brain.MethodsWe used wild‐type and Olig1‐null mice subjected to neonatal stroke and postnatal neural progenitor cultures, and we analyzed Olig1 expression in human postmortem samples from neonates that suffered HI encephalopathy (HIE).ResultsOlig1‐null neonatal mice showed significant hypomyelination after moderate neonatal stroke. Surprisingly, damaged white matter tracts in Olig1‐null mice lacked Olig2+ OPCs, and instead proliferating neuronal precursors and GABAergic interneurons were present. We demonstrate that Noggin‐induced OPC production requires Olig1 function. In postnatal neural progenitors, Noggin governs production of OLs versus interneurons through Olig1‐mediated repression of Dlx1/2 transcription factors. Additionally, we observed that Olig1 and the BMP signaling effector, phosphorylated SMADs (Sma‐ and Mad‐related proteins) 1, 5, and 8, were elevated in the subventricular zone of human infants with HIE compared to controls.InterpretationThese findings indicate that Olig1 has a critical function in regulation of postnatal neural progenitor cell production in response to Noggin. Ann Neurol 2017;81:560–571
Optomechanical Control of Quantum Yield in Trans–Cis Ultrafast Photoisomerization of a Retinal Chromophore Model
Authors: Valentini Alessio , Rivero Daniel , Zapata Felipe , García‐Iriepa Cristina , Marazzi Marco , Palmeiro Raúl , Fdez. Galván Ignacio , Sampedro Diego , Olivucci Massimo , Frutos Luis Manuel 
Published: March 2017

AbstractThe quantum yield of a photochemical reaction is one of the most fundamental quantities in photochemistry, as it measures the efficiency of the transduction of light energy into chemical energy. Nature has evolved photoreceptors in which the reactivity of a chromophore is enhanced by its molecular environment to achieve high quantum yields. The retinal chromophore sterically constrained inside rhodopsin proteins represents an outstanding example of such a control. In a more general framework, mechanical forces acting on a molecular system can strongly modify its reactivity. Herein, we show that the exertion of tensile forces on a simplified retinal chromophore model provokes a substantial and regular increase in the trans‐to‐cis photoisomerization quantum yield in a counterintuitive way, as these extension forces facilitate the formation of the more compressed cis photoisomer. A rationale for the mechanochemical effect on this photoisomerization mechanism is also proposed.
A Sixteen‐Membered Au8P8 Macrocycle Based on Gold(I) and Diphospha(III)guanidine
Authors: Adhikari Anup K. , Sárosi Menyhárt B. , Grell Toni , Lönnecke Peter , Hey‐Hawkins Evamarie 
Published: March 2017

AbstractThe reaction of cyclo‐P4Mes4C(NCy) (1) with two equivalents of [AuCl(tht)] (tht=tetrahydrothiophene) resulted in the formation of unusual sixteen‐membered Au–P macrocycle 2. This macrocycle contains diphospha(III)guanidinate as a coordinating ligand, which is formed by P−P bond cleavage of 1. Macrocycle 2 was characterized by multinuclear NMR spectroscopy, mass spectrometry and X‐ray crystallography.
Internally 2,5‐Thienylene‐Bridged [46]Decaphyrin: (Annuleno)annulene Network Consisting of Möbius Aromatic Thia[28]hexaphyrins and Strong Hückel Aromaticity of its Protonated Form
Authors: Soya Takanori , Mori Hirotaka , Hong Yongseok , Koo Yun Hee , Kim Dongho , Osuka Atsuhiro 
Published: March 2017

AbstractInternally 1,3‐phenylene‐ and 2,5‐thienylene‐bridged [46]decaphyrins 2 and 3 have been synthesized. While 2 shows modest aromatic character derived from the global 46π‐conjugated circuit, 3 displays larger aromatic character owing to the contribution of an (annuleno)annulene‐type network consisting of two twisted Möbius aromatic thia[28]hexaphyrin segments in addition to the global 46π‐network. Upon protonation, these [46]decaphyrins underwent large structural changes to acquire strong aromaticity. Protonated 3 has been revealed to take on a planar structure composed of fused two triangular thia[28]hexaphyrin segments.
Biobased nanocomposites based on collagen, cellulose nanocrystals, and plasticizers
Authors: Rodrigues Ana Pacheli Heitmann , de Souza Sâmara Durães , Gil Camila Silva Brey , Pereira Fabiano Vargas , de Oliveira Luiz Carlos Alves , de Oliveira Patricio Patrícia S. 
Published: March 2017

ABSTRACTCollagen (Col) is extensively used in various applications, including pharmaceutical, agricultural, and food applications. The materials based in Col may exhibit properties of biomedical interest because of their low toxicity, high structural capacity support, controlled biodegradability, and biocompatibility. However, Col has poor thermal and mechanical properties. The addition of plasticizers (Plas's) and fillers is an established strategy for enhancing the properties of the resulting nanocomposites. In this study, nanocomposites based on Col and cellulose nanocrystals were developed in two different ways and with three different Plas's. These materials were subjected to structural, thermal, mechanical, and morphological analysis. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 44954.
Surgery and trauma care providers' perception of the impact of dual-practice employment on quality of care provided in an Andean country
Authors: LaGrone L N , Isquith-Dicker L N , Huaman Egoavil E , Herrera-Matta J J , Fuhs A K , Ortega Checa D , Revoredo F , Rodriguez Castro M J A , Mock C N 
Published: March 2017

Abstract

Background
Dual-practice, simultaneous employment by healthcare workers in the public and private sectors is pervasive worldwide. Although an estimated 30 per cent of the global burden of disease is surgical, the implications of dual practice on surgical care are not well understood.

Methods
Anonymous in-depth individual interviews on trauma quality improvement practices were conducted with healthcare providers who participate in the care of the injured at ten large hospitals in Peru's capital city, Lima. A grounded theory approach to qualitative data analysis was employed to identify salient themes.

Results
Fifty interviews were conducted. A group of themes that emerged related to the perceived negative and positive impacts of dual practice on the quality of surgical care. Participants asserted that the majority of physicians in Lima working in the public sector also worked in the private sector. Dual practice has negative impacts on physicians' time, quality of care in the public sector, and surgical education. Dual practice positively affects patient care by allowing physicians to acquire management and quality improvement skills, and providing incentives for research and academic productivity. In addition, dual practice provides opportunities for clinical innovations and raises the economic status of the physician.

Conclusion
Surgeons in Peru report that dual practice influences patient care negatively by creating time and human resource conflicts. Participants assert that these conflicts widen the gap in quality of care between rich and poor. This practice warrants redirection through national-level regulation of physician schedules and reorganization of public investment in health via physician remuneration.
Less is more: Online consumer ratings' format affects purchase intentions and processing
Authors: Kostyk Alena , Niculescu Mihai , Leonhardt James M. 
Published: March 2017

AbstractOnline customer ratings of products and services are commonplace in e‐commerce; however, the format in which these ratings are presented to consumers can vary. Although not anticipated by classical models of decision making, latter models such as prospect theory and feelings‐as‐information theory suggest that the presentation format of online customer ratings could affect subsequent consumer decision making. In the present research, 3 empirical studies test whether online customer ratings' formats differentially affect consumer purchase intentions. The results offer support for feeling‐as‐information theory and suggest that online ratings presented in a mean (vs. distribution) format result in higher purchase intentions as a result of increased processing fluency. Implications for the presentation of online consumer ratings in e‐commerce, based on these findings, are addressed.
Neurocysticercosis a public health problem
Authors: Jácome Sánchez Elisa Carolina , Correa Díaz Edgar Patricio , Martinez Burbano Braulio , Ortiz Yépez María Angélica , García Castillo María Ariana 
Published: March 2017

Key Clinical MessageNeurocysticercosis is a parasitic disease of the central nervous system that constitutes a public health problem in endemic regions. Here, we present a patient with epilepsy and cognitive impairment due to neurocysticercosis. A public health intervention could eradicate this disease in endemic regions such as Ecuador.
Risk of malignancy in 22q11.2 deletion syndrome
Authors: Stevens Toer , van der Werff ten Bosch Jutte , De Rademaeker Marjan , Van Den Bogaert Ann , van den Akker Machiel 
Published: March 2017

Key Clinical Message22q11.2DS is a significant health problem because of its fairly high incidence. It is relevant to be vigilant regarding the diagnosis of cancer amongst 22q11.2 patients as there might be an increased risk, especially amongst patients with the 22q11.2 distal deletion syndrome.
Enhanced Electrochemical Performance in Ni‐Doped LiMn2O4‐Based Composite Cathodes for Lithium‐Ion Batteries
Authors: Deng Yunlong , Mou Jirong , Wu Huali , Zhou Lin , Zheng Qiaoji , Lam Kwok Ho , Xu Chenggang , Lin Dunmin 
Published: March 2017

AbstractHigh‐voltage and high‐performance Ni‐doped LiMn2O4‐basedcomposite cathodes have been obtained from the nominal formula of Li2Mn1‐xNixSiO4, synthesized by using a citric acid‐assisted sol‐gel method. The spinel Li(Mn,Ni)2O4 and layered Li2SiO3 coexist in the composites with x=0 and 0.05, whereas the materials with x=0.15 and 0.25 consist of Li(Mn,Ni)2O4, Li2SiO3 and layered LiNiO2; at x≥ 0.35, the impurity phases of NiO and Ni6MnO8 are detected. A significant improvement in discharge capacity and rate performance of the materials has been caused by the simultaneous existence of LiNiO2 and Li2SiO3. The composite with x=0.25 givesa very high initial discharge capacity of 168 mAh g−1 in the potential range of 3–5 V and exhibits an excellent rate performance. Our study shows that the composites consisting of Li(Mn, Ni)2O4, Li2SiO3, and LiNiO2may be promising candidates for high‐voltage and high‐performance lithium‐ion batteries.
Metal–Organic Synthetic Transporters (MOST): Efficient Chloride and Antibiotic Transmembrane Transporters
Authors: Kempf Julie , Schmitzer Andreea R. 
Published: March 2017

AbstractWe present the synthesis of two functionalized 2,4,7‐triphenylbenzimidazole ligands and demonstrate the formation of their respective metal assemblies in phospholipid membranes. Anion transport experiments demonstrate the formation of metal–organic synthetic transporters (MOST) directly in phospholipid membranes. The formation of MOST in phospholipid membranes results in efficient architectures for chloride transport. We also demonstrate the insertion of these ligands and the formation of their metal–organic assemblies in bacterial membranes; the use of MOST makes the membranes of resistant bacteria more permeable to antibiotics. We also demonstrate that a combination of MOST with tetracycline lowers the sensitivity of resistant bacteria to tetracycline by 60‐fold.
Exploration of Inflammatory Bowel Disease in Mice: Chemically Induced Murine Models of Inflammatory Bowel Disease (IBD)
Authors: Gadaleta Raffaella Maria , Garcia‐Irigoyen Oihane , Moschetta Antonio 
Published: March 2017

AbstractInflammatory bowel disease (IBD) is a chronic multifactorial inflammatory disorder characterized by periods of activation and remission of intestinal inflammation, with potentially severe complications, that can lead to mortality. Experimental animal models of intestinal inflammation are crucial for understanding the pathogenesis of Crohn's disease (CD) and ulcerative colitis (UC), the two major human IBD phenotypes. Animal models have been instrumental in unveiling the molecular background of IBD, and although a single model is not able to capture the complexity of this disease, each of them provided valuable insight into its different aspects. Chemically induced models of intestinal inflammation, mainly dextran sodium sulfate (DSS)‐ and 2,4,6‐trinitrobenzenesulfonic acid (TNBS)‐induced colitis, are widely used. This article describes DSS‐ and TNBS‐induced colitis models and their relevance to IBD pathophysiology and pre‐clinical therapeutic management. © 2017 by John Wiley & Sons, Inc.
The effects of priming in a cued dot‐probe task on appearance‐related attentional biases in women
Authors: Lane Ben R. , Mulgrew Kate E. , Mahar Doug , White Melanie J. , Loughnan Siobhan A. 
Published: March 2017

AbstractThe dot‐probe task (DPT) is a reaction time measure of attentional bias. Research using this task has found inconsistent patterns of appearance‐related attentional biases in women. This study examined the effects of a novel priming variation of the DPT, which incorporated additional cues into each trial of the task, on measurement of such biases. The study also examined associations between these biases and body image, a component of eating disorder symptomatology. A convenience sample of women from the general community (N = 103) completed body image measures online and attended a laboratory session to complete one of four DPTs: (1) an appearance‐cued DPT containing images of thin‐ideal models between each trial; (2) neutral‐cued DPT containing images of forests; (3) time‐delayed DPT controlling for time in place of an image; or (4) typical DPT containing only word stimuli. Women who completed the appearance‐cued DPT demonstrated a stronger attentional bias for positive, but not negative, appearance words than women who completed the other DPT versions. Furthermore, for the appearance‐cued and time‐delayed DPTs, this bias correlated with poorer body image across several indicators (appearance evaluation, body dissatisfaction, self‐evaluative salience of appearance, and state body satisfaction). Although it was unexpected that no attentional bias for negative‐appearance words was found, the attentional bias for positive‐appearance words may suggest that effects were driven by the ego‐threat of positive‐appearance words. Further research is warranted to determine whether such biases contribute to and maintain body image disturbance and disordered eating.