bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Après la guerre’: John Redmond, the Irish Volunteers and Armed Constitutionalism, 1913–1915
Authors: McConnel James 
Published: February 2017

Abstract
The received narrative of the Ulster crisis relegates John Redmond to the role of bystander as parliamentary politics were sidelined by paramilitarism. Only the First World War, in this account, arrested the advance of armed force in Irish politics. This article seeks to disrupt this narrative by demonstrating that Redmondites were not untouched by the militarist turn which Ireland experienced in these years. Instead, home rulers developed an armed strategy of their own in response to the advent of militant extra-parliamentary politics. Having taken over the Irish Volunteers in spring 1914, Redmondites began to arm their supporters in defence of self-government. Separatists were scornful of these efforts, and it is true that Redmondites initially saw this activity primarily in political terms. But the outbreak of war persuaded Redmond that the eventual return of loyalist soldiers to Ireland at the end of the conflict could be decisive if the Ulster crisis resumed. Believing that nationalists needed to plan for this contingency, Ireland’s prime minister-in-waiting resolved to use the war to build a home rule army. Initially, pro-war nationalists hoped that this could be achieved through the Volunteers becoming a government-sponsored home guard, but War Office opposition forced Redmond to the conclusion that only British military service could ensure a sufficient force to secure the future of self-government. Though this strategy of armed constitutionalism had unravelled by Easter 1916, that it was attempted suggests that late Redmondism should not be conceived of only in terms of Redmond’s public rhetoric of orange and green reconciliation through common battlefield sacrifice.
Charles II, Lucy Walter, and the Stuart Courts in Exile
Authors: Greenspan Nicole 
Published: February 2017

Abstract
This article examines the challenges to maintaining royal authority during periods of exile by focusing on the relationship between Charles II and Lucy Walter, who became the king’s mistress and the mother of his firstborn child James, the future Duke of Monmouth. As a king in exile, Charles was without recourse to the machinery and institutions of government. While Charles and his agents often found it difficult to secure the obedience of his subjects and of other members of the royal family, Lucy Walter proved to be particularly troublesome in this regard. Lucy’s actions highlight at once the resourcefulness, relative freedom, and precarious position of exiles. As an unwed mother and former mistress, she lacked financial stability and spent the last decade of her short life in search of support from various quarters. The relationship between Charles II and Lucy Walter therefore sheds important light on central aspects of the experience of exile, the extent of royal authority, and the limitations and opportunities encountered by king and exiles alike.
Utilization and in-hospital complications of cardiac resynchronization therapy: trends in the United States from 2003 to 2013
Authors: Hosseini Seyed Mohammadreza , Moazzami Kasra , Rozen Guy , Vaid Jeena , Saleh Ahmed , Kevin Heist E. , Vangel Mark , Ruskin Jeremy N. 
Published: February 2017

Abstract

Aims
Cardiac resynchronization therapy (CRT) device implantation has been shown to reduce morbidity and mortality in selected patients with heart failure. We sought to investigate the utilization and in-hospital complications of cardiac resynchronization therapy defibrillator (CRT-D) and pacemaker (CRT-P) implantations in the United States from 2003 to 2013.

Methods and results
Patients receiving CRT-D or CRT-P were identified in the National Inpatient Sample database (NIS), using the International Classification of Diseases-Ninth Revision-Clinical Modification procedure codes. Annual implantation rates, patient demographics, co-morbidities, in-hospital complications, and length of stay were analysed. From 2003 to 2013, an estimated total of 439 010 (95% CI: 406 723–471 296) inpatient CRT implantations were performed in the U.S. The median age of patients was 72 and 71% were male. Overall, 6.1% had at least one complication. During the study period, comorbidity index and overall complication rate increased (P = 0.002 and P = 0.01, respectively). Mortality and length of stay showed no significant trend. Predictors of complications included: age 65 and older, female sex (OR: 1.19; 95% CI: 1.12–1.27), Deyo–Charlson Comorbidity Index, and elective admission (OR: 0.61; 95% CI: 0.57–0.66).

Conclusion
From 2003 to 2013, the severity of comorbid conditions increased and a rising trend was observed in the rate of periprocedural complications among patients undergoing CRT in the United States. In-hospital mortality and length of stay showed no uniform trend.
Location and source characteristics of the 2016 January 6 North Korean nuclear test constrained by InSAR
Authors: Wei Meng 
Published: February 2017

Summary
The interferometric synthetic aperture radar (InSAR) data from the Japan Aerospace Exploration Agency ALOS-2 satellite show possible deformation associated with the 2016 January 6 North Korean nuclear test whereas the European Space Agency Sentinel-1A data are decorrelated. This is the first time that deformation related to a nuclear test has been measured since 1992. Here, I present two interpretations of the observed deformation: First, the deformation can be explained by a triggered landslide on the western slope of Mt Mantap, with a displacement of up to 10 cm across a patch of 1 km2. Second, the observation may be from uplift created by the nuclear explosion. In the second interpretation, the location, depth and cavity size can be estimated from a topography-corrected homogenous half-space model (Mogi). The preferred location of the 2016 January 6 event is 41.2993°N 129.0715°E, with an uncertainty of 100 m. The estimated depth is 420–700 m and the cavity radius is 23–27 m. Based on empirical data and the assumption of granite as the host rock, the yield is estimated to be 11.6–24.4 kilotons of TNT, which is consistent with previous results based on seismic data. With these two interpretations, I demonstrate that InSAR data provide an independent tool to locate and estimate source characteristics of nuclear tests in North Korea. The ambiguity of interpretation is mainly due to the limited InSAR data acquisition. Future frequent data collection by current and upcoming InSAR satellites will allow full use of InSAR for nuclear monitoring and characterization in North Korea and around the world.
Realizing the promise of The Partnership for Maternal, Newborn and Child Health
Authors: Fassil Hareya , Borrazzo John , Greene Richard , Jacobs Troy , Norton Maureen , Stanton Mary Ellen , Kuo Nana Taona , Rogers K , Pearson Luwei , Chaiban Ted , Banerjee Anshu , Kuruvilla Shyama , Seaone Marta , Starrs Ann , McCallon Betsy , Germann Stefan , Mohan Anshu , Bustreo Flavia , Fogstad Helga , Mishra C K 
Published: February 2017

Abstract
Reflecting on Storeng and Béhague (“Lives in the balance”: the politics of integration in the Partnership for Maternal, Newborn and Child Health. Health Policy and Planning Storeng and Béhague (2016).) historical ethnography of the Partnership for Maternal, Newborn and Child Health (PMNCH), this commentary provides a more current account of PMNCH’s trajectory since its inception in 2005. It highlights PMNCH’s distinct characteristics and how it is positioned to play an instrumental role in the current global health landscape.
Reassessment of the life cycle of the pteropod Limacina helicina from a high resolution interannual time series in the temperate North Pacific
Authors: Wang Kang , Hunt Brian P. V. , Liang Cui , Pauly Daniel , Pakhomov Evgeny A. 
Published: February 2017

AbstractLimacina helicina is the dominant pelagic gastropod mollusc species in temperate and polar ecosystems, where it contributes significantly to food webs and vertical flux. Currently, considerable uncertainty exists in the interpretation of L. helicina’s life cycle, hindering our understanding of its potential responses to environmental change. Here, we present size-frequency data on L. helicina collected from three consecutive years (2008–2010) in a North Pacific temperate fjord. Two methods of length-frequency analysis were used to infer the growth of L. helicina, i.e. linking successive means extracted from finite-mixture distributions, and using the ELEFAN software to fit seasonally oscillating versions of the von Bertalanffy growth equation to the available length-frequency data. Against a background of continuous low level spawning between spring and autumn, both approaches identified two sets of major cohorts, i.e. (i) spring cohorts (G1) spawned in March/April by (ii) overwintering cohorts (G). G overwintered with minimal to low growth, before undergoing rapid growth the following spring and completing the cycle by spawning the G1 generation and disappearing from the population by May/June. Our findings are discussed in the context of L. helicina response to climate change.
Temperature-based spawning habitat selection by capelin (Mallotus villosus) in Newfoundland
Authors: Crook Kevin A. , Maxner Emily , Davoren Gail K. 
Published: February 2017

Abstract
The location of reproduction is a key life history trait, as it influences the bio-physical conditions that offspring experience and, thus, fitness. Capelin Mallotus villosus is a small (&lt; 200 mm), short-lived forage fish that spawns in two habitats in coastal Newfoundland: warm beaches and cool, deep water (15–40 m). From 2009 to 2014, we investigated temperature-dependent spawning habitat use by quantifying hourly temperature at spawning sites during July within each habitat along with population-level spawning site use. Capelin did not spawn at sites with temperatures &lt;2 °C or consistently &gt;12 °C, supporting the estimated suitable spawning temperature range (2–12 °C). Spawning typically occurred exclusively at beaches early in July when deep-water habitat was too cold (i.e. &lt;2 °C), and then switched to deep-water habitat later in July when beaches became too warm (i.e. &gt;12 °C). Spawning overlapped for 1–3 d in both habitats when temperatures were within suitable ranges (2011, 2013), but capelin also spawned exclusively in one habitat when temperatures remained suitable in the other. The latter suggests that other factors influence spawning habitat selection, such as conspecific egg densities and other environmental conditions. Overall, the flexible use of spawning habitats, along with wide tolerance ranges of capelin eggs to environmental conditions, are likely key adaptations to maximize fitness and stabilize population dynamics of this important forage fish species in an unpredictable environment.
Shifts in spawning phenology of cod linked to rising sea temperatures
Authors: McQueen Kate , Marshall C. Tara 
Published: February 2017

AbstractWarming temperatures caused by climate change have the potential to impact spawning phenology of temperate marine fish as some species have temperature-dependent gonadal development. Inter-annual variation in the timing of Atlantic cod (Gadus morhua) spawning in the northern North Sea, central North Sea and Irish Sea was estimated by calculating an annual peak roe month (PRM) from records of roe landings spanning the last three decades. A trend towards earlier PRM was found in all three regions, with estimates of shifts in PRM ranging from 0.9 to 2.4 weeks per decade. Temperatures experienced by cod during early vitellogenesis correlated negatively with PRM, suggesting that rising sea temperatures have contributed to a shift in spawning phenology. A concurrent reduction in the mean size of spawning females excluded the possibility that earlier spawning was due to a shift in size structure towards larger individuals, as large cod spawn earlier than smaller-sized individuals in the North Sea. Further research into the effects of climate change on the phenology of different trophic levels within the North Sea ecosystem should be undertaken to determine whether climate change-induced shifts in spawning phenology will result in a temporal mismatch between cod larvae and their planktonic prey.
Crowdsourcing Consumer Research
Authors: Goodman Joseph K , Paolacci Gabriele 
Published: February 2017

Abstract
Data collection in consumer research has progressively moved away from traditional samples (e.g., university undergraduates) and toward Internet samples. In the last complete volume of the Journal of Consumer Research (June 2015–April 2016), 43% of behavioral studies were conducted on the crowdsourcing website Amazon Mechanical Turk (MTurk). The option to crowdsource empirical investigations has great efficiency benefits for both individual researchers and the field, but it also poses new challenges and questions for how research should be designed, conducted, analyzed, and evaluated. We assess the evidence on the reliability of crowdsourced populations and the conditions under which crowdsourcing is a valid strategy for data collection. Based on this evidence, we propose specific guidelines for researchers to conduct high-quality research via crowdsourcing. We hope this tutorial will strengthen the community’s scrutiny on data collection practices and move the field toward better and more valid crowdsourcing of consumer research.
Public Sector Wage Policy and Labor Market Equilibrium: A Structural Model
Authors: Bradley Jake , Postel-Vinay Fabien , Turon Hélène 
Published: February 2017

Abstract
We develop and estimate a structural model that incorporates a sizeable public sector in a labor market with search frictions. The wage distribution and the employment rate in the public sector are taken as exogenous policy parameters. Overall wage distribution and employment rate are determined within the model, taking into account the private sector’s endogenous response to public sector employment policies. Job turnover is sector specific and transitions between sectors depend on the worker’s decision to accept alternative employment in the same or different sector by comparing the value of employment in the current and prospective jobs. The model is estimated on British data by a method of moments. We use the model to simulate the impact of various counterfactual public sector wage and employment policies.
Estimation of whole-body radiation exposure from brachytherapy for oral cancer using a Monte Carlo simulation
Authors: Ozaki Y. , Watanabe H. , Kaida A. , Miura M. , Nakagawa K. , Toda K. , Yoshimura R. , Sumi Y. , Kurabayashi T. 
Published: February 2017

Abstract
Early stage oral cancer can be cured with oral brachytherapy, but whole-body radiation exposure status has not been previously studied. Recently, the International Commission on Radiological Protection Committee (ICRP) recommended the use of ICRP phantoms to estimate radiation exposure from external and internal radiation sources. In this study, we used a Monte Carlo simulation with ICRP phantoms to estimate whole-body exposure from oral brachytherapy. We used a Particle and Heavy Ion Transport code System (PHITS) to model oral brachytherapy with 192Ir hairpins and 198Au grains and to perform a Monte Carlo simulation on the ICRP adult reference computational phantoms. To confirm the simulations, we also computed local dose distributions from these small sources, and compared them with the results from Oncentra manual Low Dose Rate Treatment Planning (mLDR) software which is used in day-to-day clinical practice. We successfully obtained data on absorbed dose for each organ in males and females. Sex-averaged equivalent doses were 0.547 and 0.710 Sv with 192Ir hairpins and 198Au grains, respectively. Simulation with PHITS was reliable when compared with an alternative computational technique using mLDR software. We concluded that the absorbed dose for each organ and whole-body exposure from oral brachytherapy can be estimated with Monte Carlo simulation using PHITS on ICRP reference phantoms. Effective doses for patients with oral cancer were obtained.
Intravenous dendritic cell administration enhances suppression of lung metastasis induced by carbon-ion irradiation
Authors: Ando Ken , Fujita Hidetoshi , Hosoi Akihiro , Ma Liqiu , Wakatsuki Masaru , Seino Ken-ichiro , Kakimi Kazuhiro , Imai Takashi , Shimokawa Takashi , Nakano Takashi 
Published: February 2017

Abstract
Carbon-ion radiotherapy (CIRT) is an advanced radiotherapy and has achieved good local control, even in tumors that are resistant to conventional photon beam radiotherapy (PBRT). However, distant metastasis control is an important issue. Recently, the combination of radiotherapy and immunotherapy has attracted the attention. In immunotherapy, dendritic cells (DCs) play a pivotal role in the anti-tumor immune system. However, the mechanisms underlying the combination therapy of DCs and radiotherapy have been unclear. In the present study, we evaluated anti-metastatic effects of this combination therapy, focused on the irradiation type and the route of DC administration, using a mouse model. C3H/He mice bearing NR-S1 cells were treated with CIRT or PBRT, using biologically equivalent doses. Subsequently, DCs were administered intratumorally (IT) or intravenously (IV). IV and IT DC administrations combined with CIRT to the local tumor, but not alone, significantly suppressed pulmonary metastasis, whereas the combination of DCs with PBRT suppressed metastasis at a relatively higher dose. Additionally, the anti-metastatic effect was greater in IV DC administration compared with in IT DC administration in both CIRT and PBRT. The expression levels of CD40 and IL-12 in DCs were significantly increased after co-culturing with CIRT-treated NR-S1 cells. In addition, IV administration of those co-cultured DCs significantly suppressed pulmonary metastasis. Furthermore, ecto-calreticulin levels from CIRT-treated NR-S1 cells significantly increased compared with those of a PBRT-treated tumor. Taken together, these results suggest that local CIRT combined with IV DCs augments an immunogenicity of the tumor cells by ecto-calreticulin expression and the maturation of DCs to stimulate anti-tumor immunity to decrease lung metastases.
Testing Verlinde's emergent gravity with the radial acceleration relation
Authors: Lelli Federico , McGaugh Stacy S. , Schombert James M. 
Published: February 2017

Abstract
It has recently been proposed that space–time and gravity may emerge from an underlying microscopic theory. In a de Sitter space–time, such emergent gravity (EG) contains an additional gravitational force due to dark energy, which may explain the mass discrepancies observed in galactic systems without the need of dark matter. For a point mass, EG is equivalent to Modified Newtonian Dynamics (MOND). We show that this equivalence does not hold for finite-size galaxies: There are significant differences between EG and MOND in the inner regions of galaxies. We confront theoretical predictions with the empirical radial acceleration relation (RAR). We find that (i) EG is consistent with the observed RAR only if we substantially decrease the fiducial stellar mass-to-light ratios; the resulting values are in tension with other astronomical estimates; (ii) EG predicts that the residuals around the RAR should correlate with radius; such residual correlation is not observed.
Stabilization, Rolling, and Addition of Other Extracellular Matrix Proteins to Collagen Hydrogels Improve Regeneration in Chitosan Guides for Long Peripheral Nerve Gaps in Rats
Authors: Gonzalez-Perez Francisco , Cobianchi Stefano , Heimann Claudia , Phillips James B. , Udina Esther , Navarro Xavier 
Published: February 2017

Abstract

BACKGROUND: Autograft is still the gold standard technique for the repair of long peripheral nerve injuries. The addition of biologically active scaffolds into the lumen of conduits to mimic the endoneurium of peripheral nerves may increase the final outcome of artificial nerve devices. Furthermore, the control of the orientation of the collagen fibers may provide some longitudinal guidance architecture providing a higher level of mesoscale tissue structure.

OBJECTIVE: To evaluate the regenerative capabilities of chitosan conduits enriched with extracellular matrix-based scaffolds to bridge a critical gap of 15 mm in the rat sciatic nerve.

METHODS: The right sciatic nerve of female Wistar Hannover rats was repaired with chitosan tubes functionalized with extracellular matrix-based scaffolds fully hydrated or stabilized and rolled to bridge a 15 mm nerve gap. Recovery was evaluated by means of electrophysiology and algesimetry tests and histological analysis 4 months after injury.

RESULTS: Stabilized constructs enhanced the success of regeneration compared with fully hydrated scaffolds. Moreover, fibronectin-enriched scaffolds increased muscle reinnervation and number of myelinated fibers compared with laminin-enriched constructs.

CONCLUSION: A mixed combination of collagen and fibronectin may be a promising internal filler for neural conduits for the repair of peripheral nerve injuries, and their stabilization may increase the quality of regeneration over long gaps.
Controversies in Spinal Trauma and Evolution of Care
Authors: Harrop James S. , Rymarczuk George N. , Vaccaro Alexander R. , Steinmetz Michael P. , Tetreault Lindsay A. , Fehlings Michael G. 
Published: February 2017

Abstract
Management of spinal trauma is a complex and rapidly evolving field. To optimize patient treatment algorithms, an understanding of and appreciation for current controversies and advancing technologies in the field of spinal trauma is necessary. Therefore, members of the AOSpine Knowledge Forum Trauma initiative used a modified Delphi method to compile a list of controversial issues and emerging technologies in the field of spinal trauma, and a list of the 14 most relevant topics was generated. A total of 45 440 manuscripts covering the breadth of spine and spinal trauma were initially identified. This broad search was then refined using the 14 categories felt to be most relevant to the current field of spinal trauma. The results were further pared down using inclusion criteria to select for the most relevant topics. The 8 remaining topics were classification schemes, treatment of vertebral compression fractures, treatment of burst fractures, timing of surgery in spinal trauma, hypothermia, the importance of global sagittal balance, lumbar subarachnoid drainage, and diffusion magnetic resonance imaging. These 8 topics were felt to be the most relevant, controversial, rapidly evolving, and most deserving of inclusion in this summary. In summary, despite recent advances, the field of spinal trauma has many ongoing points of controversy. We must continue to refine our ability to care for this patient population through education, research, and development. It is anticipated that the new AOSpine fracture classification system will assist with prospective research efforts.