bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facile Approaches to Phosphorescent Bis(cyclometalated) Pentafluorophenyl PtIV Complexes: Photophysics and Computational Studies
Authors: Giménez Nora , Lara Rebeca , Moreno M. Teresa , Lalinde Elena 
Published: March 2017

AbstractA convenient and general strategy for the synthesis of stable bis(cyclometalated) pentafluorophenyl PtIV complexes fac‐[Pt(C^N)2(C6F5)Cl] (3 a–f) and mer‐[Pt(C^N)2(C6F5)(CN)] (4 c,d) has been developed. Complexes 3 were selectively generated by low‐temperature oxidation of the cyclometalated PtII complexes [Pt(C^N)(HC^N)(C6F5)] 2 [prepared from cis‐[Pt(C6F5)2(HC^N)2] (1) intermediates] with PhICl2 and subsequent metalation of the pendant HC^N ligand. Complexes 3 a,b were also alternatively generated by irradiation (Hg lamp, 400 W) of complexes 2 a,b, respectively, in CH2Cl2. This latter reaction proceeds via the hydride PtIV species cis‐[Pt(C^N)2(C6F5)H], detected as the only intermediate species. The molecular structures of 1 a,d, 2 a, and 3 a,b,d,e were confirmed by X‐ray diffraction. The substitution of Cl− by CN− in fac‐[Pt(C^N)2(C6F5)Cl] [C^N=2‐phenylbenzothiazole (3 c), 2‐(4‐bromophenyl)benzothiazole (3 d)] evolved with isomerization to give rise to the isomers (OC‐6–42)‐[Pt(C^N)2(C6F5)(CN)] (4 c, 4 d) having a mer disposition of the cyclometalated and C6F5 groups (X‐ray, 4 c). All the complexes are luminescent and their electronic spectra have been compared and interpreted with the aid of time‐dependent DFT calculations.
Asymmetric Arylative Dearomatization of β‐Naphthols Catalyzed by a Chiral Phosphoric Acid
Authors: Li Xiao‐Qiang , Yang Hui , Wang Jiao‐Jiao , Gou Bo‐Bo , Chen Jie , Zhou Ling 
Published: March 2017

AbstractAn enantioselective arylative dearomatization reaction of β‐naphthols with quinone monoimides has been developed for the first time using a chiral phosphoric acid as the catalyst, the desired enantioenriched cyclohexadienones were prepared with excellent yields and enantioselectivities by a domino Michael addition and aromatization process (up to 99 % yield, up to 98 % ee). This process is operationally simple and readily scaled up, as well as a broad substrate scope which includes 1‐substituted‐2‐naphthols with/without 3‐substituents. Furthermore, this organocatalytic procedure allows the lowering of catalyst loading to 0.5 mol % without considerable loss in reactivity and enantioselectivity.
COSY‐ und HSQC‐NMR‐Spektroskopie
Authors: Findeisen Matthias , Siehl Hans Ullrich , Berger Stefan 
Published: March 2017

ZusammenfassungDer gegenwärtige Stand der Routine 2D COSY‐ und HSQC‐NMR Spektroskopie wird geschildert. Nach einer knappen Einführung in die zu Grunde liegende Theorie des 2D‐NMR werden die Pulssequenzen für COSY und HSQC erläutert. Anhand eines Beispiels aus der Naturstoffchemie wird die Vorgehensweise bei der Analyse dieser Spektren erläutert.
QM/MM(ABEEM) Study on the Ligand Substitution Processes of Ruthenium(III) Complex NAMI‐A
Authors: Li Hui , Sun Ting‐Ting , Zhang Chao , Liu Linlin , Zhao Dongxia , Yang Zhongzhi 
Published: March 2017

AbstractQM combined with ABEEMσπ (atom‐bond electronegativity equalization method) fluctuating charge polarizable force field [QM/MM(ABEEM)] has been employed to investigate the hydrolysis mechanism of ruthenium(III) complex NAMI‐A. Eleven possible hydrolysis paths of NAMI‐A and its hydrolysates have been unveiled. Structures obtained by QM/MM (ABEEM) method were used to calculate the activation free energy by free energy perturbation theory. Based on analysis of structures and activation free energies, it is found that the rate of DMSO dissociation is faster than that of Cl− dissociation in the first step, which is in agreement with experimental results. Hydrolysates of the first step continue to hydrolyze with lower activation free energies than that of the first hydrolysis step, but the trans‐position Cl− hydrolysis in the second step needs more time to perform. This can account for experimental phenomenon reasonably. We have simulated further hydrolysis paths of the hydrolysates, then found that both Cl− dissociation and DMSO dissociation take place in the third hydrolysis step and [RuCl(H2O)4(Im)]2+ is the main solute in aqueous solution after the fourth hydrolysis step.
Effect of Communication Quality Degradation on Web Usability over 6to4 Networks
Authors: MIZOGUCHI TOMOHIKO , ITO YOSHIHIRO , KOYASHIKI RYO 
Published: March 2017

SUMMARYThis paper evaluates effect on the overheads caused by 6to4 tunneling on QoE for Web services by experiment. The authors consider Web usability as QoE and treat three actual Web services which support both of the IPv4 Internet and the IPv6 Internet. The results show that the effect of QoS degradation caused by 6to4 on Web usability depends on the Web service. According to Web service, QoE degradation caused by 6to4 does not always occur.
Fabrication of Metamaterial Absorbers in THz Region and Evaluation of the Absorption Characteristics
Authors: ISHII YUTA , TAKIDA YUMA , KANAMORI YOSHIAKI , MINAMIDE HIROAKI , HANE KAZUHIRO 
Published: March 2017

SUMMARYMetamaterial absorbers with various sizes were experimentally demonstrated in the terahertz frequency region, and their absorption characteristics were evaluated. They consist of an Au ground plate, a polyimide layer, and Au metamaterial structures. Two types of metamaterial absorbers with crossed shapes and cut‐wire shapes were fabricated, respectively. For both types of metamaterials absorbers, 90% of absorption was experimentally obtained around 1.5 THz frequencies.
Surface‐Enhanced Raman Spectroscopy Analysis Device with Gold Nanoparticle Arranged Nanochannel
Authors: TAKESHITA TOSHIMITSU , SUEKUNI KEISUKE , AIBA KIYOHITO , SUGANO KOJI , ISONO YOSHITADA 
Published: March 2017

SUMMARYA micro/nanofluidic device containing linearly arranged gold nanoparticles embedded in nanochannels was developed for highly sensitive surface‐enhanced Raman spectroscopy (SERS). The Si nanochannel array was fabricated using a photolithography‐based process. Synthesized colloidal particles of mean diameter 100 nm were arranged linearly in the nanochannels, using a nanotrench‐guided self‐assembly process. The particle geometry provides significant Raman enhancement by matching the polarization direction of the incident light to the connection direction of the particles. The SERS spectrum was obtained from 1‐mM 4,4’‐bipyridine solution using the fabricated micro/nanofluidic SERS device. The directionally arranged particles showed the same polarization angle dependency as the simulated result. The molecule was detected from 10‐pM solution using the particle arrangement. We confirmed that the particle arrangement was appropriate for highly sensitive SERS.
Performance of PM Motor Driven by PWM Inverter with Voltage Booster Using Both Flux Weakening Control and DC Link Voltage Control
Authors: IMAKIIRE AKIHIRO , YAMAMOTO KICHIRO , HIKITA MASAYUKI 
Published: March 2017

SUMMARYIn this paper, a driving method for an interior permanent magnet (IPM) motor is proposed; this method increases the system efficiency in the constant power region. In the driving method, the pulse width modulation inverter with a voltage booster system allows the use of both flux weakening control (FWC) and dc link voltage control (DVC) to drive an IPM motor at high speed. The authors investigate how a combination of FWC and DVC is suitable for the system. First, a simulation model is introduced. This model allows the calculation of the system efficiency and each part of the system losses in the voltage booster, inverter, and IPM motor. Furthermore, the system efficiency is calculated using the simulation model, and the simulation results are discussed when the ratio between the FWC and the DVC is changed. The IPM motor drive method is expected to help achievement of high efficiency by adjusting the ratio between the two control methods in the constant power region.
Design for Electromagnetic Device by Multiobjective Optimization using Genetic Programming
Authors: ISHIKAWA KOTA , KITAGAWA WATARU , TAKESHITA TAKAHARU 
Published: March 2017

SUMMARYThis paper presents a multiobjective optimization using genetic programming (GP). In this method, an analysis model is regarded as a tree structure. This tree structure is divided into polygons and material information. Therefore, this method can be applied GP. Additionally, authors take into consideration about shape complexity. The target of electromagnetic device is an interior permanent magnetic synchronous motor (IPMSM). This method optimizes flux barriers in IPMSM by two‐dimensional finite element method. The purpose of this paper is an investigation of design optimization by multiobjective optimization. Authors reveal the Pareto optimal solutions of characteristics for average torque and torque ripple of IPMSM.
Interactive effects of genotype and food quality on consumer growth rate and elemental content
Authors: Prater Clay , Wagner Nicole D. , Frost Paul C. 
Published: March 2017

AbstractConsumer body stoichiometry is a key trait that links organismal physiology to population and ecosystem‐level dynamics. However, as elemental composition has traditionally been considered to be constrained within a species, the ecological and evolutionary factors shaping consumer elemental composition have not been clearly resolved. To this end, we examined the causes and extent of variation in the body phosphorus (P) content and the expression of P‐linked traits, mass specific growth rate (MSGR), and P use efficiency (PUE) of the keystone aquatic consumer Daphnia using lake surveys and common garden experiments. While daphnid body %P was relatively constrained in field assemblages sampled across an environmental P gradient, unique genotypes isolated from these lakes showed highly variable phenotypic responses when raised across dietary P gradients in the laboratory. Specifically, we observed substantial inter‐ and intra‐specific variation and differences in daphnid responses within and among our study lakes. While variation in Daphnia body %P was mostly due to plastic phenotypic changes, we documented considerable genetic differences in daphnid MSGR and PUE, and relationships between MSGR and body P content were highly variable among genotypes. Overall, our study found that consumer responses to food quality may differ considerably among genotypes and that relationships between organismal life‐history traits and body stoichiometry may be strongly influenced by genetic and environmental variation in natural assemblages.
Effects of native diversity, soil nutrients, and natural enemies on exotic invasion in experimental plant communities
Authors: Heckman Robert W. , Halliday Fletcher W. , Wilfahrt Peter A. , Mitchell Charles E. 
Published: March 2017

AbstractMany factors can promote exotic plant success. Three of these factors—greater pressure from natural enemies on natives, increased soil nutrient supply, and low native species richness—may interact during invasions. To test for independent and interactive effects of these drivers, we planted herbaceous perennial communities at two levels of native richness (monocultures and five‐species polycultures). We then factorially manipulated soil nutrient supply and access to these communities by aboveground foliar enemies (fungal pathogens and insect herbivores), and allowed natural colonization to proceed for four years. We predicted that nutrient addition would increase exotic success, while enemy exclusion and increasing native richness would reduce exotic success. Additionally, we expected that enemy exclusion would reduce the benefits of nutrient addition to exotic species most in species‐poor communities, and that this effect would be weaker in species‐rich communities. In total, we found no evidence that nutrient supply, enemy access, and native richness interacted to influence exotic success. Furthermore, native richness had no effect on exotic success. Instead, nutrient addition increased, and enemy exclusion decreased, exotic success independently. As predicted, enemy exclusion reduced exotic success, primarily by slowing the decline in abundance of planted native species. Together, these results demonstrate that multiple drivers of exotic success can act independently within a single system.
Giant cell myocarditis masquerading as orbital myositis with a rapid, fulminant course necessitating mechanical support and heart transplantation
Authors: Garg Vinisha , Tan Weiyi , Ardehali Reza , Shah Janki , Huynh Tracy , Aksoy Olcay 
Published: March 2017

AbstractGiant cell myocarditis (GCM), a rapidly progressive inflammation of the myocardium, is associated with fulminant heart failure, refractory ventricular arrhythmias, and conduction system abnormalities. Few case reports have noted orbital myositis as the initial clinical presentation. Our case demonstrates a unique presentation of GCM with only ocular symptoms, which unlike prior studies, rapidly progressed to heart failure, tachyarrhythmias, and conduction disease. Our case necessitated quick recognition and treatment with mechanical support making this the first known case of GCM with successful placement of biventricular assist devices and ultimately with heart transplantation.
Clinical characteristics of patients from the worldwide registry on peripartum cardiomyopathy (PPCM)
Authors: Sliwa Karen , Mebazaa Alexandre , Hilfiker‐Kleiner Denise , Petrie Mark C. , Maggioni Aldo P. , Laroche Cecile , Regitz‐Zagrosek Vera , Schaufelberger Maria , Tavazzi Luigi , van der Meer Peter , Roos‐Hesselink Jolien W. , Seferovic Petar , van Spandonck‐Zwarts Karin , Mbakwem Amam , Böhm Michael , Mouquet Frederic , Pieske Burkert , Hall Roger , Ponikowski Piotre , Bauersachs Johann 
Published: March 2017

AbstractAimsThe purpose of this study is to describe disease presentation, co‐morbidities, diagnosis and initial therapeutic management of patients with peripartum cardiomyopathy (PPCM) living in countries belonging to the European Society of Cardiology (ESC) vs. non‐ESC countries.Methods and resultsOut of 500 patients with PPCM entered by 31 March 2016, we report on data of the first 411 patients with completed case record forms (from 43 countries) entered into this ongoing registry. There were marked differences in socio‐demographic parameters such as Human Development Index, GINI index on inequality, and Health Expenditure in PPCM patients from ESC vs. non‐ESC countries (P < 0.001 each). Ethnicity was Caucasian (34%), Black African (25.8%), Asian (21.8%), and Middle Eastern backgrounds (16.4%). Despite the huge disparities in socio‐demographic factors and ethnic backgrounds, baseline characteristics are remarkably similar. Drug therapy initiated post‐partum included ACE inhibitors/ARBs and mineralocorticoid receptor antagonists with identical frequencies in ESC vs. non‐ESC countries. However, in non‐ESC countries, there was significantly less use of beta‐blockers (70.3% vs. 91.9%) and ivabradine (1.4% vs. 17.1%), but more use of diuretics (91.3% vs. 68.8%), digoxin (37.0% vs. 18.0%), and bromocriptine (32.6% vs. 7.1%) (P < 0.001). More patients in non‐ESC vs. ESC countries continued to have symptomatic heart failure after 1 month (92.3% vs. 81.3%, P < 0.001). Venous thrombo‐embolic events, arterial embolizations, and cerebrovascular accidents were documented in 28 of 411 patients (6.8%). Neonatal death rate was 3.1%.ConclusionPPCM occurs in women from different ethnic backgrounds globally. Despite marked differences in socio‐economic background, mode of presentation was largely similar. Embolic events and persistent heart failure were common within 1 month post‐diagnosis and required intensive, multidisciplinary management.
ArtinM Binding Effinities and Kinetic Interaction with Leukemia Cells: A Quartz Crystal Microbalance Bioelectroanalysis on the Cytotoxic Effect
Authors: Pesquero Naira C. , Carvalho Fernanda C. , Faria Ronaldo C. , Roque‐Barreira Maria‐Cristina , Bueno Paulo R. 
Published: March 2017

AbstractArtinM, a D‐mannose‐binding lectin from Artocarpus heterophyllus (jackfruit), interacts with N‐glycosylated receptors on the surface of several cells of hematopoietic origin, triggering cell migration, degranulation, and cytokine release. Because malignant transformation is often associated with altered expression of cell surface glycans, we evaluated the interaction of ArtinM with human myelocytic leukemia cells by Quartz Cristal Microbalance (QCM) and cross compared this investigation with cellular responses (cytotoxicity) to lectin binding by the colorimetric assay MTT, which is a standard method in biology. QCM analysis was able to provide additional information (not possible to be obtained by MTT) that impact on the knowledge of medical biology related to leukemic cells. For instance, it was shown that association rate constant of ArtinM and cellular membranes (obtained from QCM) of leukemia cell varies across the myeloid leukemia cell lines, decreasing as cytotoxic effect increases. Meanwhile no differences were observed for dissociation rate constants so that the equilibrium binding affinity constant was observed to be a direct function of the association rate event. It was supposed that ArtinM cytotoxicity is affected by the association time with glycans on the cellular membranes of leukemia cells in a way that the higher it is the association time (the lower was the association rate constant) the higher is the ArtinM cytotoxicity over the leukemia cell lines.
Testing the utility of structure‐from‐motion photogrammetry reconstructions using small unmanned aerial vehicles and ground photography to estimate the extent of upland soil erosion
Authors: Glendell Miriam , McShane Gareth , Farrow Luke , James Mike R. , Quinton John , Anderson Karen , Evans Martin , Benaud Pia , Rawlins Barry , Morgan David , Jones Lee , Kirkham Matthew , DeBell Leon , Quine Timothy A. , Lark Murray , Rickson Jane , Brazier Richard E. 
Published: March 2017

AbstractQuantifying the extent of soil erosion at a fine spatial resolution can be time consuming and costly; however, proximal remote sensing approaches to collect topographic data present an emerging alternative for quantifying soil volumes lost via erosion. Herein we compare terrestrial laser scanning (TLS), and both unmanned aerial vehicle (UAV) and ground photography (GP) structure‐from‐motion (SfM) derived topography. We compare the cost‐effectiveness and accuracy of both SfM techniques to TLS for erosion gully surveying in upland landscapes, treating TLS as a benchmark. Further, we quantify volumetric soil loss estimates from upland gullies using digital surface models derived by each technique and subtracted from an interpolated pre‐erosion surface. Soil loss estimates from UAV and GP SfM reconstructions were comparable to those from TLS, whereby the slopes of the relationship between all three techniques were not significantly different from 1:1 line. Only for the TLS to GP comparison was the intercept significantly different from zero, showing that GP is more capable of measuring the volumes of very small erosion features. In terms of cost‐effectiveness in data collection and processing time, both UAV and GP were comparable with the TLS on a per‐site basis (13.4 and 8.2 person‐hours versus 13.4 for TLS); however, GP was less suitable for surveying larger areas (127 person‐hours per ha−1 versus 4.5 for UAV and 3.9 for TLS). Annual repeat surveys using GP were capable of detecting mean vertical erosion change on peaty soils. These first published estimates of whole gully erosion rates (0.077 m a−1) suggest that combined erosion rates on gully floors and walls are around three times the value of previous estimates, which largely characterize wind and rainsplash erosion of gully walls. Copyright © 2017 John Wiley & Sons, Ltd.
Excess Mortality After Pelvic Fractures Among Older People
Authors: Andrich Silke , Haastert Burkhard , Neuhaus Elke , Neidert Kathrin , Arend Werner , Ohmann Christian , Grebe Jürgen , Vogt Andreas , Jungbluth Pascal , Thelen Simon , Windolf Joachim , Icks Andrea 
Published: March 2017

ABSTRACT

The study aimed to estimate excess mortality in patients aged 60 years or older up to 1 year after pelvic fracture compared with a population without pelvic fracture. In this retrospective population-based observational study, we use routine data from a large health insurance in Germany. For each patient with a first pelvic fracture between 2008 and 2010 (n = 5685 cases, 82% female, mean age 80 ± 9 years), about 34 individuals without pelvic fracture (n = 193,159 controls) were frequency matched by sex, age at index date, and index month. We estimated survival probabilities in the first year after the index date separated for cases (further stratified into inpatient/outpatient treated or minor/major pelvic fractures) and controls using Kaplan-Meier curves. Additionally, time-dependent hazard ratios (HRs) measuring excess mortality in 4-week intervals up to 52 weeks were estimated by fitting Cox regression models including adjustment for relevant confounders. Twenty-one percent of cases and 11% of controls died within 1 year. HRs (95% confidence intervals) decreased from 3.9 (3.5–4.5) within the first 4 weeks to 1.4 (1.1–1.9) within weeks 49 to 52 after the index date. After full adjustment, HRs lowered substantially (3.0 [2.6–3.4] and 1.0 [0.8–1.4]) but were still significantly increased up to week 32. Adjusted HRs in women were lower than in men: 2.8 (2.4–3.2) and 1.0 (0.7–1.4) versus 3.8 (2.9–5.0) and 1.2 (0.6–2.3). We found a clear excess mortality among older people in the first 8 months after pelvic fracture even after full adjustment. Excess mortality was higher among men in the beginning as well as for inpatient-treated persons. Absence of excess mortality was noticed for outpatient-treated persons within the first 3 months. When broken down into site-specific data, excess mortality was no longer significant for most pelvic fractures classified as minor. The only exception was fracture of pubis within the first 4 weeks. © 2017 American Society for Bone and Mineral Research.
Bilateral massive perirenal subcapsular effusion: A case report
Authors: Yilmaz Sercan , Zor Murat , Ersan Mehmet , Hamcan Salih 
Published: March 2017

ABSTRACTBilateral perirenal subcapsular effusion is a rare condition with several underlying etiologies. A 27‐year‐old woman presented with a 3‐day history of bilateral flank pain and edema on the dorsum of her feet. Imaging, biochemical, and clinical evaluations revealed bilateral massive perirenal subcapsular effusion secondary to nephrotic syndrome. The patient was successfully treated with bilateral percutaneous drainage. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 45:597–599, 2017
The syntheses of [13C6] and [phenyl‐14C(U)]BMS‐816336, an inhibitor of 11β‐hydroxysteroid dehydrogenase type 1, for type 2 diabetes
Authors: Maxwell Brad D. 
Published: March 2017

Type 2 diabetes is a significant worldwide health problem. To support the development of BMS‐816336 as an inhibitor of 11β‐hydroxysteroid dehydrogenase type 1 for type 2 diabetes, the synthesis of carbon‐14 labeled material was required for use in metabolic profiling. [Phenyl‐14C(U)]BMS‐816336 was synthesized in 8 steps and 22% radiochemical yield from commercially available [14C(U)]bromobenzene. The radiochemical purity of [phenyl‐14C(U)]BMS‐816336 was 100% having a specific activity of 84.4 μCi/mg or 28.8 mCi/mmol for a total of 8.9 mCi. It was also necessary to synthesize [13C6]BMS‐816336 for use as a liquid chromatography/mass spectrometry standard. [13C6]BMS‐816336 was also prepared in 8 labeled steps in 26% yield from [13C6]bromobenzene.