bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rethinking creative industries research: Synthesizing the Creative Class thesis, clustering, and global production network approaches
Authors: Wu Di 
Published: November 2017

AbstractIdentifying three prevalent approaches—Richard Florida's consumption‐related Creative Class thesis, clustering of the creative industries, and global production networks of these industries—to understand the geography and development of the creative industries in existing literature, this paper reviews the significance and limitations of these approaches. It argues that existing literature treat these approaches “stand alone” from each another, without acknowledging the importance of other actors and forces. Instead, these three dynamics do not function separately, but are interdependent and complementary. It points to a critical agenda for future research, arguing that it is the intersection and synergy between these three dynamics that together shapes the development of the creative industries. This paper calls for further research, first, to examine the interrelationship between the local and the global scales of the creative industries by adopting the Global Production Networks (GPN) approach and, second, to study the association between the consumption‐related urban amenities and the production of the creative industries.
Sunscreen formulations do not interfere with sweat cooling during exercise
Authors: Ou‐Yang H. , Meyer K. , Houser T. , Grove G. 
Published: November 2017

AbstractObjectiveSweating plays a critical role in maintaining thermal balance and keeping skin cool during exercise. People often wear sunscreens on hot summer days for sun protection. Most recreational sunscreens are designed to be water‐ and sweat‐resistant, so that sweating will not remove or compromise the protection. The objective of this study was to determine whether wearing sweat‐resistant sunscreen might impede natural sweating, potentially interfering with thermal regulation and resulting in the elevation of skin temperature.MethodsWe conducted a controlled, randomized, split‐face and split‐arm clinical study with 24 female subjects wearing an SPF 70 lotion sunscreen on half of the face and an SPF 70 spray sunscreen on one of the forearms at a dosage of 2 mg cm−2. Following sunscreen application, subjects participated in two sessions of indoor exercise to induce clearly visible sweating.ResultsWe found that both skin temperatures and sweat evaporation rates were significantly elevated after each session, yet there were no significant differences in either skin temperatures or sweat rates between the treated and untreated control sites at any time point for any of the skin sites measured.ConclusionWe conclude that the application of tested sweat‐resistant sunscreen lotions and sprays does not have any measurable effects on skin cooling by natural sweating process. People should continue to use these sunscreens during recreational activities.
Financial literacy among university students: A study in eight European countries
Authors: Ergün Kutlu 
Published: November 2017

AbstractThis study analysed the level of financial literacy among university students in Estonia, Germany, Italy, Netherlands, Poland, Romania, Russian Federation and Turkey. The purpose of the study was to determine the level of financial literacy among university students, and to find out the relationship between financial knowledge and demographic characteristics of students. Online survey instrument was used to collect data. 409 fully completed questionnaires were accepted for analysis. Logistic regression was used to analyse of impact of the demographic characteristics on financial literacy. Overall mean of correct answers for the survey was 72.2%. This result represents a medium level of financial literacy about personal finance. Results indicate that male students, business major students, PhD students, those who live in a rental house, those whose parents have high level income, those who get advice on financial matters from their friends, those who took financial course before, those who get financial information about financial issues from university education, and students from Poland are more knowledgeable on personal finance. More financial courses should be provided in university education programmes, which could help more students handle their finances better and improve their financial wellbeing. It should be taken into consideration that in recent years, environmental and technological influences on financial literacy may be more important than parental influence.
Prenatal traffic‐related air pollution exposures, cord blood adipokines and infant weight
Authors: Alderete T. L. , Song A. Y. , Bastain T. , Habre R. , Toledo‐Corral C. M. , Salam M. T. , Lurmann F. , Gilliland F. D. , Breton C. V. 
Published: November 2017

SummaryObjectiveStudies suggest that prenatal exposure to traffic‐related air pollution (TRAP) may contribute to childhood obesity. While exact mechanisms for this association are unknown, circulating adipokines are hypothesized to contribute to early‐life weight gain.MethodsThe Maternal and Child Health Study birth cohort included 136 women from the Los Angeles County + University of Southern California Medical Center. This study estimated prenatal residential TRAP exposure and used linear regression analysis to examine associations between adipokines with TRAP exposure and infant weight change (birth to 6 months).ResultsA one standard deviation (1‐SD: 2 ppb) increase in prenatal non‐freeway nitrogen oxides was associated with 33% (P = 0.01) higher leptin and 9% higher high molecular weight adiponectin levels (P = 0.07) in cord blood. Leptin levels were 71% higher in mothers who lived <75 m than those living >300 m from major roadways (P = 0.03). A 1‐SD (10 ng mL−1) increase in leptin was associated with a significant increase in infant weight change in female infants (0.62 kg, P = 0.02) but not male infants (0.11 kg, P = 0.48).ConclusionsHigher TRAP exposures were associated with higher cord blood levels of leptin and high molecular weight adiponectin. These adipokines were associated with increased infant weight change in female infants, which may have implications for future obesity risk.
Binary oxide ceramics for enhanced phenols degradation under simulated Solar light
Authors: Carević Milica V. , Abazović Nadica D. , Savić Tatjana D. , Novaković Tatjana B. , Pjević Dejan J. , Čomor Mirjana I. 
Published: November 2017

AbstractSolvothermal synthesis of ZrO2–TiO2 binary oxides and pure counterparts at 150°C in water/isopropanol media is presented. Titanium (IV) isopropoxide and zirconium (IV) propoxide were used as precursors. XRD and TEM techniques were used for structural and morphological characterization of obtained samples. XPS spectra of mixed oxide samples were compared in order to correlate composition of samples with surface properties and presence of defects. Relative positions of defect states within band‐gaps of semiconductors were estimated from UCPL spectra. UV‐Vis DRS spectra revealed that both pure oxides experienced red shift of absorption thresholds compared to reference data. Photocatalytic activities of all samples were probed under simulated Solar light on three model compounds: phenol, 4‐chlorophenol (4‐CP) and 2, 4, 6‐trichlorphenol (TCP). Pure TiO2 showed the highest photocatalytic activity in the case of phenol. However, pure ZrO2 and binary oxides showed higher photoactivity in degradation of 4‐CP and TCP. The activity of wide band‐gap semiconductors under simulated Solar light in photodegradation of phenol and its derivatives is most probably the consequence of formation of charge transfer complexes between pollutant molecules and semiconductors surface.
The experience of stigma in inflammatory bowel disease: An interpretive (hermeneutic) phenomenological study
Authors: Dibley Lesley , Norton Christine , Whitehead Elizabeth 
Published: November 2017

AbstractAimTo explore experiences of stigma in people with inflammatory bowel disease.BackgroundDiarrhoea, urgency and incontinence are common symptoms in inflammatory bowel disease. Social rules stipulate full control of bodily functions in adulthood: poor control may lead to stigmatization, affecting patients’ adjustment to disease. Disease‐related stigma is associated with poorer clinical outcomes, but qualitative evidence is minimal.DesignAn interpretive (hermeneutic) phenomenological study of the lived experience of stigma in inflammatory bowel disease.MethodsForty community‐dwelling adults with a self‐reported diagnosis of inflammatory bowel disease were recruited purposively. Participants reported feeling stigmatized or not and experiencing faecal incontinence or not. Unstructured interviews took place in participants’ homes in the United Kingdom (September 2012 – May 2013). Data were analysed using Diekelmann's interpretive method.FindingsThree constitutive patterns—Being in and out of control, Relationships and social Support and Mastery and mediation—reveal the experience of disease‐related stigma, occurring regardless of continence status and because of name and type of disease. Stigma recedes when mastery over disease is achieved through development of resilience—influenced by humour, perspective, mental well‐being and upbringing (childhood socialization about bodily functions). People travel in and out of stigma, dependent on social relationships with others including clinicians and tend to feel less stigmatized over time.ConclusionEmotional control, social support and mastery over disease are key to stigma reduction. By identifying less resilient patients, clinicians can offer appropriate support, accelerating the patient's path towards disease acceptance and stigma reduction.
Escitalopram oxalate induces apoptosis in U‐87MG cells and autophagy in GBM8401 cells
Authors: Chen Vincent Chin‐Hung , Hsieh Yi‐Hsien , Chen Li‐Jeng , Hsu Tsai‐Ching , Tzang Bor‐Show 
Published: November 2017

AbstractGlioblastoma multiforme (GBM) is recognized as a most aggressive brain cancer with the worst prognosis and survival time. Owing to the anatomic location of gliomas, surgically removing the tumour is very difficult and avoiding damage to vital brain regions during radiotherapy is impossible. Therefore, therapeutic strategies for malignant glioma must urgently be improved. Recent studies have demonstrated that selective serotonin reuptake inhibitors (SSRIs) have cytotoxic effect on certain cancers. Considering as a more superior SSRI, escitalopram oxalate exhibits favourable tolerability and causes generally mild and temporary adverse events. However, limited information is revealed about the influence of escitalopram oxalate on GBM. Therefore, an attempt was made herein to explore the effects of escitalopram oxalate on GBM. The experimental results revealed that escitalopram oxalate significantly inhibits the proliferation and invasive ability of U‐87MG cells and significantly reduced the expressions of cell cycle inhibitors such as Skp2, P57, P21 and P27. Notably, escitalopram oxalate also induced significant apoptotic cascades in U‐87MG cells and autophagy in GBM8401 cells. An animal study indicated that escitalopram oxalate inhibits the proliferation of xenografted glioblastoma in BALB/c nude mice. These findings implied that escitalopram oxalate may have potential in treatment of glioblastomas.
Analysis of current thyroid function test ordering practices
Authors: Kluesner Joseph K. , Beckman Darrick J. , Tate Joshua M. , Beauvais Alexis A. , Kravchenko Maria I. , Wardian Jana L. , Graybill Sky D. , Colburn Jeffrey A. , Folaron Irene , True Mark W. 
Published: November 2017

AbstractRationaleCurrent guidelines recommend thyroid stimulating hormone (TSH) alone as the best test to detect and monitor thyroid dysfunction, yet free thyroxine (FT4) and free triiodothyronine (FT3) are commonly ordered when not clinically indicated. Excessive testing can lead to added economic burden in an era of rising healthcare costs, while rarely contributing to the evaluation or management of thyroid disease.ObjectiveTo evaluate our institution's practice in ordering thyroid function tests (TFTs) and to identify strategies to reduce inappropriate FT4 and FT3 testing.MethodsA record of all TFTs obtained in the San Antonio Military Health System during a 3‐month period was extracted from the electronic medical record. The TFTs of interest were TSH, FT4, thyroid panel (TSH + FT4), FT3, total thyroxine (T4), and total triiodothyronine (T3). These were categorized based on the presence or absence of hypothyroidism.ResultsBetween August 1 and October 31, 2016, there were 38 214 individual TFTs ordered via 28 597 total laboratory requests; 11 486 of these requests were in patients with a history of hypothyroidism. The number (percent) of laboratory requests fell into these patterns: TSH alone 14 919 (52.14%), TSH + FT4 7641 (26.72%), FT3 alone 3039 (10.63%), FT4 alone 1219 (4.26%), TSH + FT4 + FT3 783 (2.74%), and others 996 (3.48%); 36.0% of TFTs ordered were free thyroid hormones. Projected out to a year, using Department of Defense laboratory costs, $317 429 worth of TFTs would be ordered, with free thyroid hormone testing accounting for $107 720.ConclusionInappropriate ordering of free thyroid hormone tests is common. In an era of rising healthcare costs, inappropriate thyroid function testing is an ideal target for efforts to reduce laboratory overutilization, which in our system, could save up to $120 000 per year. Further evaluation is needed to determine strategies that can reduce excessive thyroid hormone testing.
Reduced blood‐brain barrier expression of fatty acid‐binding protein 5 is associated with increased vulnerability of APP/PS1 mice to cognitive deficits from low omega‐3 fatty acid diets
Authors: Pan Yijun , Choy Kwok H. C. , Marriott Philip J. , Chai Siew Y. , Scanlon Martin J. , Porter Christopher J. H. , Short Jennifer L. , Nicolazzo Joseph A. 
Published: November 2017

Lower levels of the cognitively beneficial docosahexaenoic acid (DHA) are often observed in Alzheimer's disease (AD) brains. Brain DHA levels are regulated by the blood‐brain barrier (BBB) transport of plasma‐derived DHA, a process facilitated by fatty acid‐binding protein 5 (FABP5). This study reports a 42.1 ± 12.6% decrease in the BBB transport of 14C‐DHA in 8‐month‐old AD transgenic mice (APPswe,PSEN1∆E9) relative to wild‐type mice, associated with a 34.5 ± 6.7% reduction in FABP5 expression in isolated brain capillaries of AD mice. Furthermore, short‐term spatial and recognition memory deficits were observed in AD mice on a 6‐month n‐3 fatty acid‐depleted diet, but not in AD mice on control diet. This intervention led to a dramatic reduction (41.5 ± 11.9%) of brain DHA levels in AD mice. This study demonstrates FABP5 deficiency and impaired DHA transport at the BBB are associated with increased vulnerability to cognitive deficits in mice fed an n‐3 fatty acid‐depleted diet, in line with our previous studies demonstrating a crucial role of FABP5 in BBB transport of DHA and cognitive function.
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Ontogeny of hallucal metatarsal rigidity and shape in the rhesus monkey (Macaca mulatta) and chimpanzee (Pan troglodytes)
Authors: Patel Biren A. , Organ Jason M. , Jashashvili Tea , Bui Stephanie H. , Dunsworth Holly M. 
Published: November 2017

AbstractLife history variables including the timing of locomotor independence, along with changes in preferred locomotor behaviors and substrate use during development, influence how primates use their feet throughout ontogeny. Changes in foot function during development, in particular the nature of how the hallux is used in grasping, can lead to different structural changes in foot bones. To test this hypothesis, metatarsal midshaft rigidity [estimated from the polar second moment of area (J) scaled to bone length] and cross‐sectional shape (calculated from the ratio of maximum and minimum second moments of area, Imax/Imin) were examined in a cross‐sectional ontogenetic sample of rhesus macaques (Macaca mulatta; n = 73) and common chimpanzees (Pan troglodytes; n = 79). Results show the hallucal metatarsal (Mt1) is relatively more rigid (with higher scaled J‐values) in younger chimpanzees and macaques, with significant decreases in relative rigidity in both taxa until the age of achieving locomotor independence. Within each age group, Mt1 rigidity is always significantly higher in chimpanzees than macaques. When compared with the lateral metatarsals (Mt2–5), the Mt1 is relatively more rigid in both taxa and across all ages; however, this difference is significantly greater in chimpanzees. Length and J scale with negative allometry in all metatarsals and in both species (except the Mt2 of chimpanzees, which scales with positive allometry). Only in macaques does Mt1 midshaft shape significantly change across ontogeny, with older individuals having more elliptical cross‐sections. Different patterns of development in metatarsal diaphyseal rigidity and shape likely reflect the different ways in which the foot, and in particular the hallux, functions across ontogeny in apes and monkeys.
The human platysma contains numerous muscle spindles
Authors: May Astrid , Bramke Silvia , Funk Richard H. W. , May Christian Albrecht 
Published: November 2017

AbstractThe mimic muscles are usually described as containing no muscle spindles. In the present publication the human platysma was reinvestigated concerning its content of corpuscular sensors. Serial sections through the platysma of seven donors revealed numerous muscle spindles but no Pacini corpuscules. The muscle spindles were located in the cranial two‐thirds of the platysma, and were evenly distributed with a tendency to have more spindles in the lateral part of the muscle. Immunohistochemical staining with S46 antibodies revealed a predominance of nuclear bag fibers. The results point to an extended function of the platysma as an afferent center of the lower face mimic muscles.
Predictors of adherence to treatment by patients with coronary heart disease after percutaneous coronary intervention
Authors: Kähkönen Outi , Saaranen Terhi , Kankkunen Päivi , Lamidi Marja‐Leena , Kyngäs Helvi , Miettinen Heikki 
Published: November 2017

Aims and objectivesTo identify the predictors of adherence in patients with coronary heart disease after a percutaneous coronary intervention.BackgroundAdherence is a key factor in preventing the progression of coronary heart disease.DesignAn analytical multihospital survey study.MethodsA survey of 416 postpercutaneous coronary intervention patients was conducted in 2013, using the Adherence of People with Chronic Disease Instrument. The instrument consists of 37 items measuring adherence and 18 items comprising sociodemographic, health behavioural and disease‐specific factors. Adherence consisted of two mean sum variables: adherence to medication and a healthy lifestyle. Based on earlier studies, nine mean sum variables known to explain adherence were responsibility, cooperation, support from next of kin, sense of normality, motivation, results of care, support from nurses and physicians, and fear of complications. Frequencies and percentages were used to describe the data, cross‐tabulation to find statistically significant background variables and multivariate logistic regression to confirm standardised predictors of adherence.ResultsPatients reported good adherence. However, there was inconsistency between adherence to a healthy lifestyle and health behaviours. Gender, close personal relationship, length of education, physical activity, vegetable and alcohol consumption, LDL cholesterol and duration of coronary heart disease without previous percutaneous coronary intervention were predictors of adherence.ConclusionsThe predictive factors known to explain adherence to treatment were male gender, close personal relationship, longer education, lower LDL cholesterol and longer duration of coronary heart disease without previous percutaneous coronary intervention.Relevance to clinical practiceBecause a healthy lifestyle predicted factors known to explain adherence, these issues should be emphasised particularly for female patients not in a close personal relationship, with low education and a shorter coronary heart disease duration with previous coronary intervention.
Dose-dependent effect of triiodothyronine on the chondrogenic differentiation of mesenchymal stem cells from the bone marrow of female rats
Authors: Assis Higor A , Elert Nathalia C , Azevedo André Luiz B P , Braga Iolanda S , Serakides Rogéria , de Melo Ocarino Natália , de Goes Alfredo M , de Paula Careta Francisco , Paneto Greiciane G , da Silva Adriana M A , Boeloni Jankerle N 
Published: November 2017

Abstract

Objectives
Verify the in-vitro effect of triiodothyronine (T3) on the chondrogenic differentiation of female rat bone marrow mesenchymal stem cells (BMMSCs) over several time periods and at several doses.

Methods
CD54 + /CD73 + /CD90 + BMMSCs from Wistar female rats were cultured in chondrogenic medium with or without T3 (0.01; 1; 100; 1000 nm). At seven, 14 and 21 days, the cell morphology, chondrogenic matrix formation and expression of Sox9 and collagen II were evaluated.

Key findings
The dose of 100 nm did not alter the parameters evaluated in any of the periods studied. However, the 0.01 nm T3 dose improved the chondrogenic potential by increasing the chondrogenic matrix formation and expression of Sox9 and collagen II in at least one of the evaluated periods; the 1 nm T3 dose also improved the chondrogenic potential by increasing the chondrogenic matrix formation and the expression of collagen II in at least one of the evaluated periods. The 1000 nm T3 dose improved the chondrogenic potential by increasing the chondrogenic matrix formation and Sox9 expression in at least one of the evaluated periods.

Conclusions
T3 has a dose-dependent effect on the differentiation of BMMSCs from female rats.
Evaluating the nutritive profile of three insect meals and their effects to replace soya bean in broiler diet
Authors: Khan S. , Khan R. U. , Alam W. , Sultan A. 
Published: November 2017

SummaryThis study was conducted to evaluate the comparative effect of maggot meal, silkworm meal and mealworm as dietary protein source on the production performance and some aspects of meat quality in broilers. In this regard, maggot meal was reared on chicken offal and poultry waste. Silkworm meal was obtained from silk industry, while mealworm was developed through beetles rearing. A total of 120‐day‐old broiler chicks were randomly divided into four groups where soya bean meal (M0) was replaced with maggot meal (M1), silkworm meal (M2) and mealworm (M3) respectively. Each group was further divided into three replicates. The study was carried out for a period of 5 weeks. Diets containing mealworm significantly reduced overall feed consumption and resulted into higher weight gain (p < .05). Lowest feed conversion ratio (FCR) was recorded for birds fed with mealworm diet (p < .05). Tenderness and juiciness of meat were higher (p < .05) in M3 compared to the control and other treatments. Mortality did not vary between the control and the treated groups. Therefore, it is concluded that insect meal is rich in essential nutrients and could be successfully used in broiler ration without compromising acceptability. In the light of this study, mealworm is the best choice in broiler ration, in comparison with maggot and silkworm.