bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monocyte Count/HDL Cholesterol Ratio and Cardiovascular Disease in Patients With Obstructive Sleep Apnea Syndrome: A Multicenter Study
Authors: Inonu Koseoglu Handan , Pazarli Ahmet Cemal , Kanbay Asiye , Demir Osman 
Published: November 2016

Background: Obstructive sleep apnea syndrome (OSAS) is an independent risk factor for cardiovascular disease (CVD). Although monocyte to high-density lipoprotein cholesterol ratio (MHR) is increasingly being implicated in cardiovascular morbidity and mortality, no study has attempted to determine the role of MHR in cardiovascular morbidity of patients with OSAS. We aimed to investigate the association between MHR and CVD in patients with OSAS and the relationship between severity of OSAS, polysomnographic parameters, and MHR. Methods: In this cohort study, patients who had undergone a full-night polysomnography for the diagnosis of OSAS were recruited. Included patients were grouped according to the apnea–hypopnea index (AHI) as mild (5-15), moderate (15-30), and severe (>30) OSAS. Patients with AHI < 5 served as the control group. The presence of heart failure, coronary artery disease, or arrhythmia was defined as CVD. Results: A total of 1050 patients were included (131 controls, 222 mild, 228 moderate, and 469 severe OSAS). The severe group had higher MHR compared with the control and other OSAS groups (9.99, 12.11, 13.65, and 20.67 in control, mild, moderate, and severe OSAS groups, respectively, P < .001). The MHRs were significantly correlated with AHI, oxygen desaturation index, and minimum O2 saturation values ( P < .001). Values of MHR were significantly higher in patients with CVD compared with those without ( P < .001). Multiple regression analysis demonstrated that MHR is an independent predictor of CVD. Conclusion: The MHR is strongly associated with CVD and the severity of OSAS and might be used as a biomarker to predict CVD in patients with OSAS.
Low Risk for Local and Systemic Complications After Primary Repair of 1626 Achilles Tendon Ruptures
Authors: Rensing Nicholas , Waterman Brian R. , Frank Rachel M. , Heida Kenneth A. , Orr Justin D. 
Published: November 2016

Introduction. Historically, Achilles tendon repairs and other surgeries about the hindfoot have demonstrated a significantly higher rate of wound healing complications and surgical site morbidity. The purpose of this study was to evaluate the comprehensive complication profile and risk factors for adverse short-term, clinical outcomes after primary repair of Achilles tendon ruptures. Methods. Between the years 2005 and 2014, all cases of primary Achilles tendon repair (Current Procedural Terminology code 27650) entered into the National Surgical Quality Improvement Project (NSQIP) database were extracted for analysis. Primary outcomes of interest were rates of total complication, reoperation, and rerupture within 30 days of index surgery. Independent risk factors associated with these selected endpoints were assessed with chi-square and logistic regression analysis and odds ratios with 95% confidence intervals were used to express relative risk. Results. Of 1626 patients with an average age of 44 years (SD 13.3), the average ASA classification was 1.69 and hypertension (20.7%), morbid obesity (8.3%), and diabetes (4.9%) were among the most common medical comorbidities. A total of 28 (1.7%) patients sustained perioperative complications, including 1.3% with local complications (0.7% superficial wound infection, 0.4% wound disruption) and no cases of peripheral nerve injury or early repair failure. Systemic complications occurred in 0.4%, most commonly with deep venous thrombosis or nonfatal thromboembolism. Preoperative albumin was independently associated with an increased risk of local wound complications (odds ratio [OR] 28.67; 95% CI 1.42-579.40; P = .029). Chronic obstructive pulmonary disease (OR 22.33, 95% CI 2.49-199.81; P = .006) and bleeding disorder (OR 14.83, 95% CI 1.70-129.50; P = .015) were more likely to result in a systemic complication, and preoperative creatinine correlated with an increased risk of any complication (OR 6.11, 95% CI 1.15-32.34; P = .033). In total there were 5 (0.3%) readmissions with 2 (0.1%) unplanned reoperations attributed to local wound complications. Conclusion. Among a broad-based demographic of the United States, the rate of local wound complications was exceedingly low in the short-term perioperative period, although this risk may be significantly magnified with subtle decreases in albumin levels. Preoperative risk stratifications should carefully scrutinize for subtle abnormalities in nutritional parameters and renal function prior to undergoing Achilles surgery. Levels of Evidence: Therapeutic, Level II: Prospective, comparative trial
Effect of a Rapidly Degrading Presolidified 10 kDa Chitosan/Blood Implant and Subchondral Marrow Stimulation Surgical Approach on Cartilage Resurfacing in a Sheep Model
Authors: Bell Angela D. , Hurtig Mark B. , Quenneville Eric , Rivard Georges-Étienne , Hoemann Caroline D. 
Published: November 2016

Objective This study tested the hypothesis that presolidified chitosan-blood implants are retained in subchondral bone channels perforated in critical-size sheep cartilage defects, and promote bone repair and hyaline-like cartilage resurfacing versus blood implant. Design Cartilage defects (10 × 10 mm) with 3 bone channels (1 drill, 2 Jamshidi biopsy, 2 mm diameter), and 6 small microfracture holes were created bilaterally in n = 11 sheep knee medial condyles. In one knee, 10 kDa chitosan–NaCl/blood implant (presolidified using recombinant factor VIIa or tissue factor), was inserted into each drill and Jamshidi hole. Contralateral knee defects received presolidified whole blood clot. Repair tissues were assessed histologically, biochemically, biomechanically, and by micro–computed tomography after 1 day ( n = 1) and 6 months ( n = 10). Results Day 1 defects showed a 60% loss of subchondral bone plate volume fraction along with extensive subchondral hematoma. Chitosan implant was resident at day 1, but had no effect on any subsequent repair parameter compared with blood implant controls. At 6 months, bone defects exhibited remodeling and hypomineralized bone repair and were partly resurfaced with tissues containing collagen type II and scant collagen type I, 2-fold lower glycosaminoglycan and fibril modulus, and 4.5-fold higher permeability compared with intact cartilage. Microdrill holes elicited higher histological ICRS-II overall assessment scores than Jamshidi holes (50% vs. 30%, P = 0.041). Jamshidi biopsy holes provoked sporadic osteonecrosis in n = 3 debrided condyles. Conclusions Ten kilodalton chitosan was insufficient to improve repair. Microdrilling is a feasible subchondral marrow stimulation surgical approach with the potential to elicit poroelastic tissues with at least half the compressive modulus as intact articular cartilage.
An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe
Authors: Ruttens David , Verleden Stijn E. , Bijnens Esmée M. , Winckelmans Ellen , Gottlieb Jens , Warnecke Gregor , Meloni Federica , Morosini Monica , Van Der Bij Wim , Verschuuren Erik A. , Sommerwerck Urte , Weinreich Gerhard , Kamler Markus , Roman Antonio , Gomez-Olles Susana , Berastegui Cristina , Benden Christian , Holm Are Martin , Iversen Martin , Schultz Hans Henrik , Luijk Bart , Oudijk Erik-Jan , Kwakkel-van Erp Johanna M. , Jaksch Peter , Klepetko Walter , Kneidinger Nikolaus , Neurohr Claus , Corris Paul , Fisher Andrew J. , Lordan James , Meachery Gerard , Piloni Davide , Vandermeulen Elly , Bellon Hannelore , Hoffmann Barbara , Vienneau Danielle , Hoek Gerard , de Hoogh Kees , Nemery Benoit , Verleden Geert M. , Vos Robin , Nawrot Tim S. , Vanaudenaerde Bart M. 
Published: November 2016

Air pollution from road traffic is a serious health risk, especially for susceptible individuals. Single-centre studies showed an association with chronic lung allograft dysfunction (CLAD) and survival after lung transplantation, but there are no large studies.13 lung transplant centres in 10 European countries created a cohort of 5707 patients. For each patient, we quantified residential particulate matter with aerodynamic diameter ≤10 µm (PM10) by land use regression models, and the traffic exposure by quantifying total road length within buffer zones around the home addresses of patients and distance to a major road or freeway.After correction for macrolide use, we found associations between air pollution variables and CLAD/mortality. Given the important interaction with macrolides, we stratified according to macrolide use. No associations were observed in 2151 patients taking macrolides. However, in 3556 patients not taking macrolides, mortality was associated with PM10(hazard ratio 1.081, 95% CI 1.000–1.167); similarly, CLAD and mortality were associated with road lengths in buffers of 200–1000 and 100–500 m, respectively (hazard ratio 1.085– 1.130). Sensitivity analyses for various possible confounders confirmed the robustness of these associations.Long-term residential air pollution and traffic exposure were associated with CLAD and survival after lung transplantation, but only in patients not taking macrolides.
Serum YKL-40 as predictor of outcome in hypersensitivity pneumonitis
Authors: Long Xiaoping , He Xuan , Ohshimo Shinichiro , Griese Matthias , Sarria Rafael , Guzman Josune , Costabel Ulrich , Bonella Francesco 
Published: November 2016

YKL-40, a chitinase-like protein mainly secreted by macrophages, neutrophils and epithelial cells, is increased in patients with idiopathic interstitial pneumonia and sarcoidosis. We aimed to investigate the role of YKL-40 as a biomarker in hypersensitivity pneumonitis (HP).72 HP patients, 100 interstitial lung disease (ILD) controls and 60 healthy controls were studied. YKL-40 was measured by ELISA in serum and bronchoalveolar lavage fluid (BALF) at baseline and follow-up. The relationship between YKL-40 levels, clinical variables and disease outcome was evaluated.Baseline serum YKL-40 levels were significantly higher in HP patients than in healthy controls (p<0.001), but lower than in patients with other ILDs. Baseline BALF YKL-40 levels in HP patients were the highest among ILD patients. In HP patients, serum YKL-40 correlated with the diffusing capacity of the lung for carbon monoxide at baseline (p<0.01) and over time (p<0.001). HP patients whose disease progressed or who died had higher baseline YKL-40 levels than those who remained stable and survived (p<0.001). At a cut-off of 119 ng·mL−1, the baseline serum YKL-40 level predicted disease progression (hazard ratio 6.567; p<0.001), and at a cut-off of 150 ng·mL−1was associated with mortality (hazard ratio 9.989; p<0.001).Serum YKL-40 may be a useful prognostic biomarker in HP patients.
Direct Measurement and Quantification of Drugs and Their Metabolites in Urine by MALDI-MS Using Zeolite
Authors: Kitaoka Chihiro , Asano Takashi , Fujino Tatsuya 
Published: November 2016

Abstract
A complex of α-cyano-4-hydroxycinnamic acid (CHCA) and zeolite was used as the matrix for the analysis of drugs and their metabolites in urine by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). It was found that acetaminophen (AAP) and its metabolites could be detected in urine without any pretreatment or separation process. It was also found that the hydrolysis of one of the metabolites, glucuronide, was promoted when a mixture of urine and the developed matrix was heated at 343 K for 15 minutes. Because of the homogeneous distribution of CHCA on the zeolite surface, high reproducibility of the analyte peak intensity was achieved. By using isotope-labeled acetaminophen (D4-AAP) as the internal standard, quantitative analysis of AAP in urine from a donor who took 300 mg of AAP four hours before was performed, and 5.29 ± 0.19 mg of AAP was detected in 1.00 g of urine.
Thin Film Properties of Ammonium Sulfonate Ionic Liquids Having a Long Alkyl Chain
Authors: Kondo Hirofumi , Hatsuda Kouki , Tano Nobuo , Baghel Pankaj , Noguchi Takeshi 
Published: November 2016

Abstract
New well-lubricated ILs including ammonium sulfonate having a long alkyl chain have been developed. The materials based on ammonium sulfonate have a higher ΔpKa between the Brønsted acid and the Brønsted base of the salts and do not decompose even at 300 °C, making them more thermally stable than the perfluoropolyether (PFPE). Therefore, octadecyl ammonium sulfonates have a lower frictional coefficient on the carbon overcoat film even after heat treatment at high temperatures. The ILs are adsorbed on the media surface with high orientation. The alkyl chains of the C16 and C18 sulfonates in the bulk have a trans conformation, nevertheless, the films have a gauche conformation. A sufficient length of the hydrocarbon chain leads to both macro and micro-friction reductions. Dimethyl ammonium sulfonate has sufficient solubility in fluorinated solvent, which may make commercial applications possible.
PTSD in victims of terroristic attacks – a comparison with the impact of other traumatic events on patients’ lives
Authors: Bossini Letizia , Ilaria Casolaro , Koukouna Despoina , Caterini Claudia , Olivola Miriam , Fagiolini Andrea 
Published: November 2016

CelTo identify possible differences, in terms of duration and severity of Post-Traumatic Stress Disorder, between victims of terroristic attacks and subjects who underwent other types of traumatic events.MetodaWe selected a sample of subjects suffering from PTSD. After a clinical interview aimed at the collection of anamnestic data, CAPS to confirm the diagnosis of PTSD and DTS to assess frequency and severity of post-traumatic symptoms were administered. One-way ANOVA was used in order to compare the differences in the parameters analyzed through the DTS scales and its clusters between the victims of terroristic attacks and patients undergone other traumatic events.WynikiThe duration of PTSD was 258 +/- 144.9 months for people who underwent a terroristic attack and 41.6 +/- 11.8 months for victims of other traumatic events. As regards the severity of the disorder, the total score of the DTS scale was 65.6 +/- 26.9 in victims of terroristic attacks and 78.2 +/- 28.2 in people undergone other traumatic events, but the difference was not statistically significant; Avoidance and Hypervigilance clusters showed an important statistical significance.WnioskiNo significant differences are present in terms of severity, showing that PTSD is a disabling disorder regardless the type of event that triggers it; but a significant difference in terms of duration of the disorder leads to reflect on the importance of an early diagnostic process aimed toward the victims of terrorism, in order to avoid the risk of chronicity and progression to other psychiatric disorders such as Depression.
The serum concentration of copper in bipolar disorder
Authors: Siwek Marcin , Styczeń Krzysztof , Sowa-Kućma Magdalena , Dudek Dominika , Reczyński Witold , Szewczyk Bernadeta , Misztak Paulina , Opoka Włodzimierz , Topór-Mądry Roman , Nowak Gabriel , Rybakowski Janusz 
Published: November 2016

Cel pracyNieliczne doniesienia naukowe wskazują na zmiany stężenia miedzi w surowicy u osób z chorobą afektywną dwubiegunową (ChAD), jednak dane te są niejednoznaczne. Celem badania było przeprowadzenie oceny stężeń miedzi w surowicy krwi pacjentów znajdujących się w różnych fazach choroby dwubiegunowej w porównaniu do grupy zdrowych ochotników, z uwzględnieniem specyficznych cech klinicznych oraz stopnia zaawansowania choroby.MetodaDo badania zakwalifikowano 133 pacjentów z rozpoznaniem ChAD (typ I, II i BNO), w tym 61 osób w epizodzie depresji, 23 osoby w stanie maniakalnym lub hipomaniakalnym i 49 pacjentów w stanie remisji. Grupa kontrolna liczyła 50 osób. Pomiaru stężenia miedzi dokonano metodą atomowej spektrometrii absorpcyjnej.WynikiNie stwierdzono istotnych statystycznie różnic w zakresie stężenia miedzi w surowicy pomiędzy pacjentami znajdującymi się w poszczególnych fazach ChAD (mania/hipomania, depresja, remisja), z rożnymi podtypami ChAD (typ I, typ II+ BNO), czy też w różnych stadiach zaawansowana choroby (staging), a grupą zdrowych ochotników. Stężenie miedzi u pacjentów znajdujących się w stadium 1 było jednak istotnie statystycznie wyższe w porównaniu do pozostałych pacjentów, znajdujących się w bardziej zaawansowanych fazach choroby (stadium 2+3+4), (β =0,22; p=0,02). Ponadto stężenie miedzi było tym wyższe im późniejszy był wiek zachorowania (β =0,33; p<0,001) oraz tym niższe im więcej było przebytych epizodów choroby (β =-0,23; p=0,02), (model regresji wielorakiej, adj R2=0,19, p=0,0001).WnioskiPrzedstawione powyżej zależności mogą odzwierciedlać procesy patofizjologiczne zachodzące w przebiegu ChAD (takie jak np. reakcja zapalna oraz stres oksydacyjny) i osiągające różną intensywność w zależności od jej zaawansowania.
Is Chineseness too big for China? Chineseness in negotiation in minoritarian practices of Organhaus art space
Authors: You Mi 
Published: November 2016

Abstract
This article aims to bring to light the heterogeneity and nomadic character of ‘Chineseness’ by mapping the curatorial practice of the Chongqing-based art space Organhaus. Their curatorial projects involving Xinjiang and Iran shall be examined through the lens of ‘minoritarian practice’, which at the same time affords a tool for unpacking the notion of Chineseness as related to empire, state and in an inter-Asian context. It shall be argued that it is through minoritarian practices that negotiation and actualization of Chineseness emerge.
Research praxis in drawing: The visible and the invisible ‘Chineseness’ – an exploration through Chinese language and the matriarchal writing script, nüshu
Authors: Lo Yuen-Yi 
Published: November 2016

Abstract
Drawing is the core of my practice. While drawing may have appeared ‘secondary’ in the western fine arts tradition, its ‘marginal’ status intrigues me. To draw through appropriating some gendered Chinese characters and a dying ‘secret’ matriarchal script nüshu, my practice is deliberate and exploratory. Working with the symbolic Chinese signs into undefined graphs and representations, I have attempted to break away from the original registrations; employing nüshu, a set of inventive writing script practiced by some women as opposed to the official language, I have examined possibilities of articulating outside the dominant culture and language of man. My ‘Chineseness’ may manifestly be ‘visible’, its ‘invisibility’ yet lies beyond the visible. It is through acts of repeated drawing and its extended manifestations that the body of work is evolving and developing. My exploration through language has led me realize that drawing, being a practice, also acts as a strategy to ‘uncover’ something that are ‘lost’ or ‘forgotten’.
Ai Weiwei’s exhibition On the Table 2014/2015 in Barcelona: A review in light of its local media reception
Authors: Manonelles Moner Laia 
Published: November 2016

Abstract
Ai Weiwei is one of the artists with greater relevance outside China. In Spain, he is one of the Chinese artists to have attained more visibility with the media and art centres, as exemplified by the first exhibition Resistencia y tradición/Resistance and Tradition at the Andalusian Contemporary Art Centre of Seville (2013), and with On the Table: Ai Weiwei at the Palau the la Virreina in Barcelona (2014–2015). It is worth noting that both exhibitions by Ai Weiwei have become the most visited in the history of the aforementioned institutions. With the aim to expand on the reception of the prolific and heterogeneous trajectory of Ai Weiwei in Spain, I will analyse the exhibition’s discourse of On the Table and its impact on the local and national media. The article will take into account the political aims of the Palau de la Virreina’s director in relating Ai Weiwei’s public persona with the political message that the Catalan institutions wished to convey in connection with the right to self-determination for Catalonia and the terms of their relationship with the Spanish state. The Palau de la Virreina opted for an artist who symbolizes – in the western media – the fight for democracy and freedom of speech. In order to delve deeper into such ideas, I will focus on the controversies and expectations that Ai Weiwei generates as an artist, as well as his role as a political activist.
‘Chineseness’ in contemporary art discourse and practice: Negotiating multiple agencies, localities and vocalities
Authors: Koch Franziska 
Published: November 2016

Abstract
This editorial contextualizes the theme of 'Chineseness' in contemporary art discourse and practice and explains how the eight (peer reviewed) scholarly articles, two artist contributions and one exhibition review respond to various constructions of ‘Chineseness’ explored in connection with competing, conflicting or supplementing agencies, localities and vocalities in the field of art. Methodologically, the pluralist approaches are motivated in light of the global turn in art history and related disciplines that have fostered a critical, epistemologically conscious transcultural approach in recent years. The issue’s insightful contributions present the result of selected and revised proceedings of the international symposium (In) direct speech. ‘Chineseness’ in contemporary art discourse and practice. Art market, curatorial practices and creative processes that took place at Lisbon University’s Faculty of Fine Arts in 2015 and discussed transculturality in connection with contemporary Chinese art. Taking together, the case studies address three overlapping aspects of ‘Chineseness’ as a) constituted in curatorial practices and institutional politics of display, b) created by individual artists and their invention or negotiation of Chinese (premodern) ‘traditions’, and c) a methodological challenge for art history given underlying, often invisible epistemological conditions and confinements.
Frankenstein’s monster as translation: Articulations of artistic creativity, individuality and freedom of expression
Authors: Aggeklint Eva 
Published: November 2016

Abstract
This article presents an interpretation of conceptual artist Qiu Zhen’s photographic work Me and My Bride: Satan’s Wedding No. 5 (2008) within the theoretical framework of Homi K. Bhabha’s Third Space. Because of its hybrid status and the work’s subtle likeness to certain visual elements related with the story of Frankenstein the interpretation is closely connected to that narrative. More specifically, the article uses this particular literary-photographical and cross-cultural panorama to explore artistic creativity, individuality and freedom of expression as articulated in this conceptual and postmodern work that was produced in the wake of preparing for the 2008 Olympic Games. The article further explores how something foreign like Frankenstein may engage with ‘Chineseness’ and how ‘Chineseness’ may be emphasized through the usage of something foreign. Thus this article approaches the concept of ‘Chineseness’ as a wearer of a foreign coat, negotiating the hybrid as a highly performative but softly speaking political product on the Chinese art scene.
The Taiwanese artist Mei Dean-E and the concept of Chineseness
Authors: Laureillard Marie 
Published: November 2016

Abstract
The artist Mei Dean-E (born in 1954) constantly questions the identity of Taiwan and especially of its Chinese component. In an era of de-Sinicization of Taiwan, to which Chineseness does this second-generation mainlander refer? Mei Dean-E, a Dada and Pop Art artist, challenging mental habits through a deconstruction of signs and symbols, gives multi-layered answers. I will argue that he never gives up his emotional relationship to Chinese culture and reinvents a form of Chineseness which is much more related with personal feelings than with official slogans or international opinions.