bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seasonal Influence on the Risk of Relapse at a Rise of Antineutrophil Cytoplasmic Antibodies in Vasculitis Patients with Renal Involvement
Authors: Kemna Michael J. , Cohen Tervaert Jan Willem , Broen Kelly , Timmermans Sjoerd A.M.E.G. , van Paassen Pieter , Damoiseaux Jan G.M.C. 
Published: February 2017

Objective.The objective of this study was to identify risk factors for a relapse at the time of an increase in antineutrophil cytoplasmic antibodies (ANCA) in patients with renal ANCA-associated vasculitis (AAV).Methods.All patients between January 2000 and November 2011 with renal AAV having an ANCA rise during remission were included. Differences in time to relapse since the ANCA rise were assessed using a Cox regression model. The level of 25-hydroxy Vitamin D (25(OH)D) was assessed at the ANCA rise and at a subsequent relapse or time-matched during remission.Results.Sixty patients had an ANCA rise, of whom 36 patients relapsed. Three risk factors were associated with a relapse at the time of the ANCA increase: previous disease activity not treated with cyclophosphamide or rituximab (HR 3.48, 95% CI 1.60–7.59), an ANCA rise during the fall season (HR 4.37, 95% CI 1.60–11.90), and an extended ANCA rise (HR 3.57, 95% CI 1.50–8.48). Levels of 25(OH)D significantly decreased during followup in relapsing patients, but not in patients who remained in remission (difference −6.3 ± 14.4, p = 0.017 vs 2.7 ± 16.3, p = 0.430).Conclusion.ANCA rises occurring during the fall season are more frequently followed by a relapse than ANCA rises occurring during other seasons. Although it is tempting to speculate that decreasing Vitamin D levels following the ANCA rise can be held responsible for the subsequent relapse, this remains to be determined.
Regards français sur la genèse d’un dialogue interrégional, l’ASEM (Asia Europe Meeting)
Authors: Badel Laurence 
Published: February 2017

Le 1er mars 1996, le Sommet de Bangkok lance le processus du Dialogue Asie-Europe (Asia Europe Meeting, ASEM) issu à la fois du rapprochement de longue durée de la Communauté européenne avec l’Asie du Sud-Est dans les années 1970 et de la conjoncture de la fin de la Guerre froide. Il permet à certains dirigeants asiatiques d’affirmer une identité asiatique fondée sur des normes politiques, économiques et sociales endogènes et aux dirigeants européens de répondre aux accusations de protectionnisme portées contre la « Forteresse Europe ». Ni organisation internationale, ni structure-cadre de négociation, l’ASEM revendique un caractère sui generis qui n’est pas sans rappeler la novation qu’avait constitué en son temps le format de la CSCE. L’enjeu est ici de conjuguer l’approche de l’« ASEAN Way » en matière de négociation avec les « valeurs et coutumes européennes ».
L’ASEM : le début d’un (mini-)pivot européen vers l’Asie-Pacifique ?
Authors: Lechervy Christian 
Published: February 2017

Conçu comme devant être « LA » plateforme de dialogue Europe – Asie, l’ASEM est un forum des relations bilatérales parmi bien d’autres. L’ASEAN en demeure un des pivots même si numériquement les États membres de l’Association ne représentent plus qu’un membre asiatique sur deux. Élargi au-delà de l’Union Européenne à l’Ouest et de l’« ASEAN + 3 » à l’Est, l’ASEM recherche encore sa configuration géographique optimale. Doit-elle s’ouvrir à de nouveaux partenaires en Asie centrale, en Asie du Sud, parmi les États insulaires du Pacifique ou encore vers les cinq États des Balkans occidentaux non-membres de l’Union européenne ? En développant une vision « continentale » des relations euro-asiatiques, l’ASEM et ses États membres européens seront mieux à même de définir leurs attentes vis-à-vis de la Chine, des États-Unis et des autres institutions trans-asiatiques (APEC, EAS...).
« La fin des chasses gardées » : l’Alliance atlantique et la « guerre froide latino-américaine » (1959-1973)
Authors: Pedemonte Rafael 
Published: February 2017

La Guerre froide ne s’est pas exprimée de manière homogène sur l’ensemble de la planète. Si certains pays du Tiers monde semblent émerger sur la scène internationale après la conférence de Bandoeng (1955), l’insertion définitive de l’Amérique latine dans la logique Est-Ouest ne survient qu’après la révolution cubaine. L’OTAN réagit au virage à gauche du régime castriste et met en place en 1961 un groupe d’experts destiné à évaluer la situation latino-américaine. Les rapports biannuels de ce comité montrent que l’action de La Havane ainsi que la présence croissante de l’URSS et de la Chine inquiètent profondément les autorités. Les craintes envers Cuba entraînent aussi un intérêt spécial à l’égard d’autres pays, notamment le Chili, où le pouvoir instaure un projet « marxiste démocratique » en 1970. Loin de créer un consensus, ces questions font l’objet de débats et reflètent les divergences stratégiques des pays occidentaux – notamment le Royaume-Uni et la Belgique – qui ne partagent pas toujours la ligne dure de Washington.
Measuring Practicing Clinicians’ Information Literacy
Authors: Dixon Brian , Barboza Katherine , Jensen Ashley , Bennett Katelyn , Sherman Scott , Schwartz Mark 
Published: February 2017

SummaryBackground: As healthcare moves towards technology-driven population health management, clinicians must adopt complex digital platforms to access health information and document care. Objectives: This study explored information literacy, a set of skills required to effectively navigate population health information systems, among primary care providers in one Veterans’ Affairs (VA) medical center.Methods: Information literacy was assessed during an 8-month randomized trial that tested a population health (panel) management intervention. Providers were asked about their use and comfort with two VA digital tools for panel management at baseline, 16 weeks, and post-intervention. An 8-item scale (range 0-40) was used to measure information literacy (Cronbach’s α=0.84). Scores between study arms and provider types were compared using paired t-tests and ANOVAs. Associations between self-reported digital tool use and information literacy were measured via Pearson’s correlations.Results: Providers showed moderate levels of information literacy (M= 27.4, SD 6.5). There were no significant differences in mean information literacy between physicians (M=26.4, SD 6.7) and nurses (M=30.5, SD 5.2, p=0.57 for difference), or between intervention (M=28.4, SD 6.5) and control groups (M=25.1, SD 6.2, p=0.12 for difference). Information literacy was correlated with higher rates of self-reported information system usage (r=0.547, p=0.001). Clinicians identified data access, accuracy, and interpretability as potential information literacy barriers.Conclusions: While exploratory in nature, cautioning generalizability, the study suggests that measuring and improving clinicians’ information literacy may play a significant role in the implementation and use of digital information tools, as these tools are rapidly being deployed to enhance communication among care teams, improve health care outcomes, and reduce overall costs.
Hypotony Management through Transconjunctival Scleral Flap Resuturing: Analysis of Surgical Outcomes and Success Predictors
Authors: Scoralick Ana Luiza B , Almeida Izabela , Ushida Michele , Dias Diego T , Dorairaj Syril , Prata Tiago S , Kanadani Fábio N 
Published: February 2017

ABSTRACT

Aim
To investigate surgical outcomes and success predictors of transconjunctival scleral flap resuturing for the management of hypotony due to overfiltration following trabeculectomy with mitomycin C.

Materials and methods
Noncomparative, retrospective, interventional case series in which all glaucoma patients from two glaucoma services undergoing transconjunctival scleral flap resuturing between May 2012 and July 2016 were enrolled. Included eyes had to have hypotony [intraocular pressure (IOP) ≤ 6 mm Hg] and/or hypotony maculopathy caused by excessive filtration following trabeculectomy. Key exclusion criteria were wound/bleb leaking and postoperative ocular trauma or infection. Preoperative and postoperative IOP, best-corrected visual acuity (BCVA), fundus imaging, surgical complications, and any subsequent related events or procedures were recorded. Rates of postsurgical hypotony and/or maculopathy resolution and possible success predictors were investigated.

Results
A total of 22 patients (22 eyes) with a mean age of 56.4 ± 15.2 years were included. Median follow-up was 245 days [interquartilerange (IR); 120–817 days] and mean IOP was increased from 2.9 ± 1.5 mm Hg (1–6 mm Hg) to 8.5 ± 3.1 mm Hg (2–16 mm Hg) at the last follow-up visit (p < 0.01). Approximately 75% of the cases (16 out of 22) had an IOP between 7 and 18 mm Hg at the end of the follow-up period. Median BCVA (log MAR) at last follow-up visit [0.1 (IR; 0.0- 0.3)] was significantly better than preoperative BCVA [0.4 (IR; 0.1-1.0); p < 0.01]. Hypotony resolved in 81% of the cases, while maculopathy resolution was found in 85% of the cases. Time interval between trabeculectomy and flap resuturing was the only factor significantly associated with patient's IOP at last follow-up visit (R2 = 0.23; p = 0.036). Success rates (IOP < 6 mm Hg at last follow-up visit) were halved in those left untreated for more than 6 months. No serious adverse event was recorded.

Conclusion
Our findings support the use of transconjunctival scleral flap resuturing as an effective and safe alternative for hypotony management due to overflitration following trabeculectomy. As time interval seems to influence the odds of hypotony resolution, early intervention is recommended.

How to cite this article
Scoralick ALB, Almeida I, Ushida M, Dias DT, Dorairaj S, Prata TS, Kanadani FN, Hypotony Management through Transconjunctival Scleral Flap Resuturing: Analysis of Surgical Outcomes and Success Predictors. J Curr Glaucoma Pract 2017;11(2):58-62.
Steroid-induced Glaucoma: An Avoidable Irreversible Blindness
Authors: Pandav SS , Kaur Savleen , Kaushik Sushmita , Phulke Sonia 
Published: February 2017

ABSTRACTSteroids are a group of anti-inflammatory drugs, commonly used to treat ocular and systemic conditions. Unmonitored use of steroids especially in eye drop formulations is common in situations when it is easily available over-the-counter, resulting in undesirable side effects.Among the ocular side effects, cataract and glaucoma are common. Steroid-induced ocular hypertension was reported in 1950, when long-term use of systemic steroid was shown to increase the intraocular pressure (IOP). Chronic administration of steroids in any form with raised IOP can cause optic neuropathy resulting in steroid-induced glaucoma.This review describes the pathophysiology and epidemio­logy of steroid-induced glaucoma, recognition of side effects, and principles of management. The purpose is to familiarize all clinicians with the potential dangers of administering steroids without monitoring the eye and the dangers of irreversible blindness in some instances of habitual self-prescription by patients.How to cite this articlePhulke S, Kaushik S, Kaur S, Pandav SS. Steroid-induced Glaucoma: An Avoidable Irreversible Blindness. J Curr Glaucoma Pract 2017;11(2):67-72.
Intraoperative Injection vs Sponge-applied Mitomycin C during Trabeculectomy: A One-year Study
Authors: Khouri Albert S , Huang Grace , Huang Linda Y 
Published: February 2017

ABSTRACT
Aim
To determine the safety and efficacy of intraoperative injection of mitomycin C (MMC) against conventional sponge-applied MMC during trabeculectomy.

Materials and methods
This study was a retrospective, comparative case series. Thirty eyes with primary open-angle glaucoma underwent consecutive trabeculectomies with MMC injection (injection group), and thirty eyes with sponge-applied MMC were as controls (sponge group). Data were collected preoperatively and postoperatively at 1 day, 1 week, 1 month, 3 months, 6 months, and 1 year after surgery. Demographic data, applanation intraocular pressure (IOP), best-corrected visual acuity (VA), number of glaucoma medications, postoperative interventions, postoperative complications, and number of visits within 3 months were recorded. In order to stratify data, proportion of eyes achieving >30% IOP reduction from baseline with or without glaucoma medications was calculated and defined as surgical success.

Results
Mean IOP reduction at 1 year was significant in both the injection and sponge groups from baseline (46.8 and 37.8% respectively). The injection group had overall lower postoperative IOP and comparable complete treatment success, defined as achieving >30% IOP reduction without glaucoma medications (p = 0.941). The number of postoperative visits within 3 months and the proportion of eyes needing 5-fluorouracil (5-FU) intervention were significantly lower in the injection group (p = 0.03, p = 0.04 respectively).

Conclusion
Injection of MMC was as safe and effective as sponge application with comparable estimated complete treatment success, less need for visits within 3 months, and 5-FU intervention.

Clinical significance
Surgeons may consider intraoperative injection of MMC in appropriate patient cohorts given comparable safety and efficacy and several advantages over traditional sponge application. Further study in a prospective, larger, long-term manner is necessary to assess this modality.

How to cite this article
Khouri AS, Huang G, Huang LY. Intraoperative Injection vs Sponge-applied Mitomycin C during Trabeculectomy: A One-year Study. J Curr Glaucoma Pract 2017;11(3):101-106.
Trend of atmospheric mercury concentrations at Cape Point for 1995–2004 and since 2007
Authors: Martin Lynwill G. , Labuschagne Casper , Brunke Ernst-Günther , Weigelt Andreas , Ebinghaus Ralf , Slemr Franz 
Published: February 2017

Abstract. Long-term measurements of gaseous elemental mercury (GEM) concentrations at Cape Point, South Africa, reveal a downward trend between September 1995 and December 2005 and an upward one from March 2007 until June 2015, implying a change in trend sign between 2004 and 2007. The trend change is qualitatively consistent with the trend changes in GEM concentrations observed at Mace Head, Ireland, and in mercury wet deposition over North America, suggesting a change in worldwide mercury emissions. Seasonally resolved trends suggest a modulation of the overall trend by regional processes. The trends in absolute terms (downward in 1995–2004 and upward in 2007–2015) are highest in austral spring (SON), coinciding with the peak in emissions from biomass burning in South America and southern Africa. The influence of trends in biomass burning is further supported by a biennial variation in GEM concentration found here and an El Niño–Southern Oscillation (ENSO) signature in GEM concentrations reported recently.
How does downward planetary wave coupling affect polar stratospheric ozone in the Arctic winter stratosphere?
Authors: Lubis Sandro W. , Silverman Vered , Matthes Katja , Harnik Nili , Omrani Nour-Eddine , Wahl Sebastian 
Published: February 2017

Abstract. It is well established that variable wintertime planetary wave forcing in the stratosphere controls the variability of Arctic stratospheric ozone through changes in the strength of the polar vortex and the residual circulation. While previous studies focused on the variations in upward wave flux entering the lower stratosphere, here the impact of downward planetary wave reflection on ozone is investigated for the first time. Utilizing the MERRA2 reanalysis and a fully coupled chemistry–climate simulation with the Community Earth System Model (CESM1(WACCM)) of the National Center for Atmospheric Research (NCAR), we find two downward wave reflection effects on ozone: (1) the direct effect in which the residual circulation is weakened during winter, reducing the typical increase of ozone due to upward planetary wave events and (2) the indirect effect in which the modification of polar temperature during winter affects the amount of ozone destruction in spring. Winter seasons dominated by downward wave reflection events (i.e., reflective winters) are characterized by lower Arctic ozone concentration, while seasons dominated by increased upward wave events (i.e., absorptive winters) are characterized by relatively higher ozone concentration. This behavior is consistent with the cumulative effects of downward and upward planetary wave events on polar stratospheric ozone via the residual circulation and the polar temperature in winter. The results establish a new perspective on dynamical processes controlling stratospheric ozone variability in the Arctic by highlighting the key role of wave reflection.
The Orbiting Carbon Observatory-2: first 18 months of science data products
Authors: Eldering Annmarie , O'Dell Chris W. , Wennberg Paul O. , Crisp David , Gunson Michael R. , Viatte Camille , Avis Charles , Braverman Amy , Castano Rebecca , Chang Albert , Chapsky Lars , Cheng Cecilia , Connor Brian , Dang Lan , Doran Gary , Fisher Brendan , Frankenberg Christian , Fu Dejian , Granat Robert , Hobbs Jonathan , Lee Richard A. M. , Mandrake Lukas , McDuffie James , Miller Charles E. , Myers Vicky , Natraj Vijay , O'Brien Denis , Osterman Gregory B. , Oyafuso Fabiano , Payne Vivienne H. , Pollock Harold R. , Polonsky Igor , Roehl Coleen M. , Rosenberg Robert , Schwandner Florian , Smyth Mike , Tang Vivian , Taylor Thomas E. , To Cathy , Wunch Debra , Yoshimizu Jan 
Published: February 2017

Abstract. The Orbiting Carbon Observatory-2 (OCO-2) is the first National Aeronautics and Space Administration (NASA) satellite designed to measure atmospheric carbon dioxide (CO2) with the accuracy, resolution, and coverage needed to quantify CO2 fluxes (sources and sinks) on regional scales. OCO-2 was successfully launched on 2 July 2014 and has gathered more than 2 years of observations. The v7/v7r operational data products from September 2014 to January 2016 are discussed here. On monthly timescales, 7 to 12 % of these measurements are sufficiently cloud and aerosol free to yield estimates of the column-averaged atmospheric CO2 dry air mole fraction, XCO2, that pass all quality tests. During the first year of operations, the observing strategy, instrument calibration, and retrieval algorithm were optimized to improve both the data yield and the accuracy of the products. With these changes, global maps of XCO2 derived from the OCO-2 data are revealing some of the most robust features of the atmospheric carbon cycle. This includes XCO2 enhancements co-located with intense fossil fuel emissions in eastern US and eastern China, which are most obvious between October and December, when the north–south XCO2 gradient is small. Enhanced XCO2 coincident with biomass burning in the Amazon, central Africa, and Indonesia is also evident in this season. In May and June, when the north–south XCO2 gradient is largest, these sources are less apparent in global maps. During this part of the year, OCO-2 maps show a more than 10 ppm reduction in XCO2 across the Northern Hemisphere, as photosynthesis by the land biosphere rapidly absorbs CO2. As the carbon cycle science community continues to analyze these OCO-2 data, information on regional-scale sources (emitters) and sinks (absorbers) which impart XCO2 changes on the order of 1 ppm, as well as far more subtle features, will emerge from this high-resolution global dataset.
Monitoring surface water quality using social media in the context of citizen science
Authors: Zheng Hang , Hong Yang , Long Di , Jing Hua 
Published: February 2017

Abstract. Surface water quality monitoring (SWQM) provides essential information for water environmental protection. However, SWQM is costly and limited in terms of equipment and sites. The global popularity of social media and intelligent mobile devices with GPS and photography functions allows citizens to monitor surface water quality. This study aims to propose a method for SWQM using social media platforms. Specifically, a WeChat-based application platform is built to collect water quality reports from volunteers, which have been proven valuable for water quality monitoring. The methods for data screening and volunteer recruitment are discussed based on the collected reports. The proposed methods provide a framework for collecting water quality data from citizens and offer a primary foundation for big data analysis in future research.
Rhetorical Trajectories from the Early Heidegger
Authors: Marshall David L. 
Published: February 2017

ABSTRACTWith the publication in 2002 of Martin Heidegger's summer semester 1924 lectures, “Basic Concepts of Aristotelian Philosophy,” a major new star appeared in the constellation that is twentieth-century rhetoric. Since then, a growing secondary literature has emerged. This article organizes that literature as a series of specifications closing in on Heidegger's critical conception of rhetoric as potentially a hermeneutic of the everydayness of being with others, and it claims that our understanding of this everydayness will remain flat or partial until we situate the concept in the sequence of Heidegger's thought in the 1920s. If we work through pre-1924, 1924, and post-1924 periods, it becomes clear that there are religious, modal, and sophistic contexts for Heidegger's evolving conceptualization of everydayness. The concept of everydayness that emerges is disheveled but rich. The article concludes by suggesting that only faint echoes of these potent rhetorical trajectories can be discerned in the late Heidegger.
Kapitalistische banken als criminele ondernemingen: de casus Wall Street
Authors: Friedrichs D.O. 
Published: February 2017

Capitalist banks as criminal enterprises
The central thesis of this article is that the structure of the present financial system, its culture, and its collective practices and policies are fundamentally criminal and criminogenic. The harms emanating from this financial system are exponentially greater than those emanating from the disadvantaged environments that generate a disproportionate percentage of conventional crime. Accordingly, on various levels, there is much at stake in more fully and directly recognizing and identifying many core policies and practices of the financial system for what they are: crimes on a very large scale.
Drie drijvende krachten achter bedrijfscriminaliteit
Authors: Brummelkamp G.W. , Huisman W. , Flikweert T. 
Published: February 2017

Three driving forces of business crime. An empirical study of fraud in small and medium sized enterprises
This article gives a report of an empirical study on business crime among small and medium sized enterprises (< 250 employees). The researchers examined 37 cases of business crime by interviewing the entrepreneurs. They were asked how the offence occurred, about their personal stake and their reflections on the interests that were impaired. Although the concept of business crime covers a huge amount of unlawful actions committed with various intentions, in the end there are three main driving forces: control, opportunity and motivation. Control refers to the entrepreneurs’ professionalism and ability to bring business processes – that can be rather complex – in line with regulations. Opportunity refers to the economic interest c.q. the (opportunity) costs of compliance. Motivation refers to the entrepreneurs’ perception of responsibility toward direct stakeholders and social values.
Faillissementsfraude: een hardnekkig fenomeen
Authors: Kemp F. 
Published: February 2017

Bankruptcy fraud: a persistent phenomenon. Plea for a preventive approach
In the Netherlands new criminal law measures will be introduced to prevent and combat bankruptcy fraud. In this article the author argues that the emphasis on criminal law measures is not sufficient to effectively tackle the phenomenon of bankruptcy fraud because prosecution and punishment always occur after the damage is done. What is needed is an integrated approach realising preventive measures, such as tools to detect fraud at an early stage. Fraud is, after all, characterised by typical behaviour that throws up digital red flags. After detecting those red flags subsequent action can be taken to stop the fraud. Also modernising the Trade Register would contribute considerably to the protection of creditors.