bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modulation instability of whistler wave with electron loss cone distribution in magnetized plasma
Authors: Zhang Heng , Ge Bin-Wen , Li Jing-Yun , Zhu Zhi-Lin , Zhou Kang 
Published: October 2024

Abstract
The modulation instability of whistler mode waves caused by thermal electron anisotropy is studied. Based on MHD equations, the nonlinear Schrödinger equation (NLSE) that describes the nonlinear modulation of whistler waves is derived by using the Krylov-Bogoliubov-Mitropolsky (KBM) method. The condition for wave modulation instability is obtained from the loss cone distribution function of thermal electron anisotropy, revealing that the nonlinear growth of the waves tends towards electron perpendicular temperature anisotropy. By setting up continuous background waves and introducing small ion low frequency perturbations, we find that the change in the amplitude of the modulated wave is related with wave number. This finding has been validated through simulations that align with our analytical results. Additionally, we also calculate the maximum amplitude of the wave with loss cone angle and times, which revealed that the electron vertical temperature anisotropy will lead to the modulation instability of the whistler wave. This further confirms the occurrence of the modulation instability of the whistler wave in laboratory plasmas and strengthens their credibility.
Entropy production of active Brownian particles going from liquid to hexatic and solid phases
Authors: Semeraro Massimiliano , Negro Giuseppe , Suma Antonio , Corberi Federico , Gonnella Giuseppe 
Published: October 2024

Abstract
Due to its inherent intertwinement with irreversibility, entropy production is a prime observable to monitor in systems of active particles. In this numerical study, entropy production in the liquid, hexatic and solid phases of a two-dimensional system of active Brownian particles is examined at both average and fluctuation level. The trends of averages as functions of density show no singularity and marked changes in their derivatives at the hexatic-solid transition. Distributions show instead peculiar tail structures interpreted by looking at microscopic configurations. Particles in regions of low local order generate tail values according to different dynamical mechanisms: they move towards empty regions or bounce back and forth into close neighbours. The tail structures are reproduced by a simple single-particle model including an intermittent harmonic potential.
Indefinitely flat rotation curves from Mpc sized charged cocoons
Authors: Nieuwenhuizen Theodorus Maria 
Published: October 2024

Abstract
Weak lensing exhibits that rotation curves of isolated galaxies remain flat up to Mpc scale (Mistele T. et al. Astrophys. J. Lett.9692024L3). Recently we proposed that dark matter is a combination of electrostatic and vacuum energy in standard physics. In this theory, isolated galaxies may be embedded in “charged cocoons”, spheres with

charge density. The related circular rotation curves decay at the Mpc scale. The analytic solution is extended to the early Universe. A peak in the cosmic microwave background spectrum is expected at the arcsec scale. The induced nanometer size of the cocoons at the Big Bang makes the initial state inhomogeneous.
Shared Genetic Architecture and Causal Relationship Between Serum 25-Hydroxyvitamin D and Bone Mineral Density
Authors: Sha Linna , Zhang Li , Zhao Xunying , Xiang Rong , Wu Xueyao , Zhu Jiangbo , Hou Jiaojiao , Deng Qin , Qin Chenjiarui , Xiao Changfeng , Qu Yang , Han Tao , Zhou Jinyu , Zheng Sirui , Yu Ting , Song Xin , Yang Bin , Fan Mengyu , Jiang Xia 
Published: October 2024

AbstractContextDespite the well-established regulatory role of vitamin D in maintaining bone health, little is known about the shared genetics and causality of the association between serum 25-hydroxyvitamin D (25OHD) and bone mineral density (BMD).ObjectiveWe aimed to investigate the shared genetic architecture and causal relationship between serum 25OHD and BMD, providing insights into their underlying biological mechanisms.MethodsLeveraging individual-level data from the UK Biobank (UKB) cohort and summary-level data from the genome-wide association studies (GWASs) conducted on European individuals for serum 25OHD (N = 417 580) and estimated heel BMD (eBMD, N = 426 824), we systematically elucidated the shared genetic architecture underlying serum 25OHD and eBMD through a comprehensive genome-wide cross-trait design.ResultsDespite a lack of global genetic correlation (rg=−0.001; P = .95), a statistically significant local signal was discovered at 5p11-5q11.9. Two-sample mendelian randomization (MR) indicated no causal association in the overall population (β=.003, 95% CI, −0.04 to 0.03; P = .93), while positive causal effects were observed in males (β=.005, 95% CI, 0.00 to 0.01; P = .03) and older individuals (β=.009, 95% CI, 0.00∼0.02; P = .01) according to one-sample MR. A total of 49 pleiotropic single-nucleotide variations (SNVs), with 4 novel SNVs (rs1077151, rs79873740, rs12150353, and rs4760401), were identified, and a total of 95 gene-tissue pairs exhibited overlap, predominantly enriched in the nervous, digestive, exocrine/endocrine, and cardiovascular systems. Protein-protein interaction analysis identified RPS9 and RPL7A as hub genes.ConclusionThis study illuminates the potential health benefits of enhancing serum 25OHD levels to mitigate the risk of osteoporosis among men and individuals older than 65 years. It also unveils a shared genetic basis between serum 25OHD and eBMD, offering valuable insights into the intricate biological pathways.
The GTPase RAB6 is required for stem cell maintenance and cell migration in the gut epithelium
Authors: Simonin Pierre , Guerrero Gehenna Lobo , Bardin Sabine , Gannavarapu Ram Venkata , Krndija Denis , Boyd Joseph , Miserey Stephanie , Vignjevic Danijela Matic , Goud Bruno 
Published: October 2024

ABSTRACT
Intestinal epithelial cells, which are instrumental in nutrient absorption, fluid regulation, and pathogen defense, undergo continuous proliferation and differentiation within the intestinal crypts, migrating towards the luminal surface where they are eventually shed. RAB GTPases are key regulators of intracellular vesicular trafficking and are involved in various cellular processes, including cell migration and polarity. Here, we investigated the role of RAB6 in the development and maintenance of the gut epithelium. We generated conditional knockout mice with RAB6 specifically deleted in the gut epithelium. We found that deletion of the Rab6a gene resulted in embryonic lethality. In adult mice, RAB6 depletion led to altered villus architecture and impaired junction integrity without affecting the segregation of apical and basolateral membrane domains. Further, RAB6 depletion slowed down cell migration and adversely affected both cell proliferation and stem cell maintenance. Notably, the absence of RAB6 resulted in a diminished number of functional stem cells, as evidenced by the rapid death of isolated crypts from Rab6a KO mice when cultured as 3D organoids. Together, these results underscore the essential role of RAB6 in maintaining gut epithelial homeostasis.
Hippo cooperates with p53 to regulate lung airway mucous cell metaplasia
Authors: Liu Jiangying , Luo Dan , Huang Haidi , Mu Rongzi , Yuan Jianghong , Jiang Ming , Lin Chuwen , Xiang Honggang , Lin Xinhua , Song Haihan , Zhang Yongchun 
Published: October 2024

ABSTRACT
Airway mucous cell metaplasia is a significant feature of many chronic airway diseases, such as chronic obstructive pulmonary disease, cystic fibrosis and asthma. However, the mechanisms underlying this process remain poorly understood. Here, we employed in vivo mouse genetic models to demonstrate that Hippo and p53 (encoded by Trp53) cooperate to modulate the differentiation of club cells into goblet cells. We revealed that ablation of Mst1 (Stk4) and Mst2 (Stk3), encoding the core components of Hippo signaling, significantly reduces mucous metaplasia in the lung airways in a lipopolysaccharide (LPS)-induced lung inflammation murine model while promoting club cell proliferation in a Yap (Yap1)-dependent manner. Additionally, we showed that deleting Mst1/2 is sufficient to suppress p53 deficiency-mediated goblet cell metaplasia. Finally, single-cell RNA-sequencing analysis revealed downregulation of YAP and p53 signaling in goblet cells in human airways. These findings underscore the important role of Hippo and p53 signaling in regulating airway mucous metaplasia.
PERSON’S CHOICE IN MORAL DILEMMAS SOLUTION SOCIONIC TYPE INFLUENCE
Authors: Ponomareva Ekaterina V. 
Published: October 2024

Background. The question of personality traits influence on a person's choice in solving moral issues is quite relevant and is widely represented in modern research in the personality psychology field. No one has conducted such studies using the socionic model yet.
Purpose. The purpose of empirical study is to test the socionic type influence on person’s choice in moral dilemmas solving.
Methodology. To conduct the research, we used methods of socionic type identification, author’s moral dilemmas solving test, factor and correlation analysis.
Results. Provided factor analysis separated all questions from author’s tests into 5 factors, which we interpret like: personal safety, personal values, following public morality regulations, following the rules and laws, safety of loved ones. Correlation analysis for the factors and socionic traits revealed a positive correlation between the factor “personal safety” and the pole “Farsighted”. “Personal values” factor showed a positive correlation with the pole “Asking” and the factor “following the rules and laws” – with the pole “Result”. The factor “following public morality regulations” revealed a positive correlation with the poles “Dynamics” and “Serious”, and the factor “safety of loved ones” showed a positive correlation with the poles “Yielding”, “Tactical” and “Emotivist”.
Practical implications. The findings contribute in definition of socionic traits clarification, to better understand their influence on observable human’s behavior. This ensures that practitioners who use socionic methods draw on the experimentally verified hypotheses.
Protocol for a prospective randomized trial of surgical versus conservative management for unstable fractures of the distal radius in patients aged 65 years and older
Authors: Bell Katrina R. , Oliver William M. , White Timothy O. , Molyneux Samuel G. , Graham Catriona , Clement Nick D. , Duckworth Andrew D. 
Published: October 2024

AimsThe primary aim of this study is to quantify and compare outcomes following a dorsally displaced fracture of the distal radius in elderly patients (aged ≥ 65 years) who are managed conservatively versus with surgical fixation (open reduction and internal fixation). Secondary aims are to assess and compare upper limb-specific function, health-related quality of life, wrist pain, complications, grip strength, range of motion, radiological parameters, healthcare resource use, and cost-effectiveness between the groups.MethodsA prospectively registered (ISRCTN95922938) randomized parallel group trial will be conducted. Elderly patients meeting the inclusion criteria with a dorsally displaced distal radius facture will be randomized (1:1 ratio) to either conservative management (cast without further manipulation) or surgery. Patients will be assessed at six, 12, 26 weeks, and 52 weeks post intervention. The primary outcome measure and endpoint will be the Patient-Rated Wrist Evaluation (PRWE) at 52 weeks. In addition, the abbreviated version of the Disabilities of Arm, Shoulder and Hand questionnaire (QuickDASH), EuroQol five-dimension questionnaire, pain score (visual analogue scale 1 to 10), complications, grip strength (dynamometer), range of motion (goniometer), and radiological assessments will be undertaken. A cost-utility analysis will be performed to assess the cost-effectiveness of surgery. We aim to recruit 89 subjects per arm (total sample size 178).DiscussionThe results of this study will help guide treatment of dorsally displaced distal radial fractures in the elderly and assess whether surgery offers functional benefit to patients. This is an important finding, as the number of elderly distal radial fractures is estimated to increase in the future due to the ageing population. Evidence-based management strategies are therefore required to ensure the best outcome for the patient and to optimize the use of increasingly scarce healthcare resources.Cite this article: Bone Jt Open 2024;5(10):920–928.
PRÁTICAS DE ECOINOVAÇÃO COMO FATOR DE DESEMPENHO EMPRESARIAL
Authors: Aragão de França Cilene , Meireles Martins Cyntia , Athayde Moreira Marcia , Quites Reis Rodrigo 
Published: October 2024

O objetivo dessa pesquisa foi analisar as práticas de ecoinovação realizadas pelas organizações localizadas no Parque de Ciência e Tecnologia Guamá, em Belém do Pará e sua relação com o desempenho. Os dados foram obtidos por meio de uma survey,o questionário foi aplicado de forma eletrônica, seus resultados foram analisados com análise fatorial e regressão os quais evidenciaram que as práticas realizadas são as criações de produtos recicláveis, redução no consumo de energia, água e treinamento ambiental. A análise da regressão múltipla mostra que entre os fatores, o que mais tem relação com o desempenho são treinamento ambiental e diminuição do consumo de materiais nocivos no processo de produção. Os resultados apontam que esta pesquisa se adiciona ao corpo teórico já existente sobre ecoinovação, identificando que o treinamento ambiental e diminuição de materiais nocivos no processo de produção são um fator relevante, que incentiva as práticas de ecoinovação e impacta em seu desempenho, seu diferencial reside em sua análise ser realizada no contexto de um território de gestão de inovações.
Stand growth and carbon stocks of community-based mangrove rehabilitation in Singkawang City, West Kalimantan, Indonesia
Authors: ASTIANI DWI , ROSLINDA EMI , WIDIASTUTI TRI , EKAMAWANTI HANNA ARTUTI , EKYASTUTI WIWIK , DWIANTO WAHYU , ALFIKRI FARIH , NGIDU EUFEMIA Y. 
Published: October 2024

Abstract. Astiani D, Roslinda E, Widiastuti T, Ekamawanti HA, Ekyastuti W, Dwianto W, Alfikri F, Ngidu EY. 2024. Stand growth and carbon stocks of community-based mangrove rehabilitation in Singkawang City, West Kalimantan, Indonesia. Biodiversitas 25: 2799-2805. The ability of tropical mangrove ecosystems to store carbon in the form of biomass is well-founded. The mangrove forest in Setapuk Besar Village, Singkawang City, West Kalimantan Province, Indonesia has been managed by community members in response to the development of alluvial sediment land in recent years. The community's efforts in Setapuk Besar Village to rehabilitate and manage mangrove forests illustrate how essential mangrove forests are to the local ecology and should be applauded for their success. This study aims to investigate the growth and development, carbon stored and sequestered in mangrove forests planted by community in Setapuk Besar between 2015 and 2020. Field survey was conducted from July to November 2022 by mapping the sediment land that had expanded since 2015 and continued with the measurement of density and diameter of mangrove stands that were systematically planted in each planting year using sampling plot method. In addition, site factors such as pH, carbon content, nitrogen, phosphorus, CEC, and soil solution salinity were investigated. Our findings indicate that due to alluvial sedimentation, the coastline in Setapuk village is expanding by 3.3 to 4.6 ha annually, accumulating 24 ha throughout a six-year period. The mangroves planted in 2015-2016 are now thriving on the new land. The six-year-old trees diameter achieved an average of 6.80±0.13 cm, averaged 5.1 m in height, and increased from 0.45 to 2.2 cm in diameter. The total biomass (above and below-ground) of plants aged 4, 5 and 6 years was 250, 303 and 430 tons ha-1, with a potential to absorb carbon of 28-33 tons ha-1 year-1, correspondingly. Given that this mangrove area plays a crucial role in CO2 capture in nature and has a relatively high ability to absorb and store carbon, conservation efforts and best practices are necessary for this forest.
Genetic diversity and population structure of Philippine strawberry germplasm based on genome-wide simple sequence repeat markers
Authors: ELEC VENUS H. , CADORNA CHARLES ANTHON E. , TAD-AWAN BELINDA A. , BASQUIAL DARWIN A. , DUMASLAN MILAGROS R. , REY JESSICA D. 
Published: October 2024

Abstract. Elec VH, Cadorna CAE, Tad-Awan BA, Basquial DA, Dumaslan MR, Rey JD. 2024. Genetic diversity and population structure of Philippine strawberry germplasm based on genome-wide simple sequence repeat markers. Biodiversitas 25: 2969-2979. Strawberry is a globally recognized fruit due to its health benefits and economic significance. Determining the level of genetic diversity and the relationship between germplasm resources involved in the breeding program is critical for effective crop improvement strategies. This study used 197 Simple Sequence Repeat (SSR) markers to assess the genetic diversity and population structure of 24 strawberry germplasm from the Benguet State University (BSU) collection. In this study, 70% of the markers used were polymorphic with reproducible fragments. A total of 792 alleles were detected, with an average of six per marker. The diversity indices indicated an intermediate level of diversity among the germplasm based on the Jaccard coefficient. Results from cluster analysis generated three groups, separating the Red Milky Way and Summer Princess cultivars from the rest of the germplasm evaluated, while a third cluster was further divided into six subgroups. Furthermore, identified clustering patterns of the evaluated genotypes showed independence from the region of origin, coinciding with Principal Component Analysis (PCA) and population structure analysis results. This study reveals the genetic diversity level and population structure of the strawberry cultivars in the Philippines using SSR markers, facilitating accurate identification and informed parental selection for breeding objectives.
Life history traits of the gastropod-associated bacterivorous nematode Caenorhabditis brenneri (Nematoda: Rhabditida)
Authors: DALAN LOEL , TAÑAN VERONICA , DIANO MICHELLE ANNE , DEMAYO CESAR , TABELIN MYLAH , SUMAYA NANETTE HOPE 
Published: October 2024

Abstract. Dalan L, Tañan V, Diano MA, Demayo C, Tabelin M, Sumaya NH. 2024. Life history traits of the gastropod-associated bacterivorous nematode Caenorhabditis brenneri (Nematoda: Rhabditida). Biodiversitas 25: 3106-3113. Caenorhabditis species are associated with decaying plant materials and invertebrates such as terrestrial gastropods. Few Caenorhabditis species have been studied regarding their ecology, genetics, development, and essential life history traits (LHT). In this study, we describe the life cycle of a free-living, wild-type, bacterivorous nematode, Caenorhabditis brenneri Sudhaus and Kiontke 2007, associated with the terrestrial slug Philippinella moellendorffi Collinge 1899 and account for the effects of food density and temperature on its population dynamics by employing the hanging drop technique. The bacterial food supply was sourced from the slug cadaver and identified as Alcaligenes faecalis (MT012081). C. brenneri was fed with varying bacterial densities (109 and 5×109 cells mL-1) and incubated at 20 and 25°C. The bacterial food density-temperature interaction was found to have no significant influence on the offspring production of C. brenneri. Moreover, the total fertility rate (TFR) and net reproductive rate (Ro) are higher in 109 cells mL-1 in both temperatures (TFR at 20°C: 139; 25°C: 169 and Ro at 20°C: 134; 25°C: 156). Whereas the alternative generation time (To, T1, T) and population doubling time (PDT) are faster at 25°C in both bacterial densities, the intrinsic rate of natural increase (rm) is faster at lower temperatures (20°C) in both bacterial densities. The average lifespan of C. brenneri is seven days when fed with A. faecalis. Offspring somatic growth (body length and width) was influenced by bacterial food density-temperature interaction with increased length and girth observed in higher bacterial density and temperature in our knowledge. This study is the first attempt to use A. faecalis, a wild-type bacterium from the terrestrial slug P. moellendorffi cadaver, as the bacterial food source for a Caenorhabditis LHT analysis.
Integratable high-efficiency achromatic metalens across the entire low-loss bands of optical fiber from 1260 to 1625  nm
Authors: Cheng Dongping , Zou Xiujuan , Wan Peng , Chen Mengdan , Li Wenjie , Zhai Yalin , Jiang Mingming , Kan Caixia 
Published: October 2024

A challenge in optic fiber is to control dispersion over the entire low-loss bands covering the O + E + S + C + L bands with integratable ultracompact devices, which inevitably limits the range of fiber-based applications. Metalens supplies a dynamic platform for correcting chromatic aberration of optical devices in a flexible, integratable, and ultracompact way. Hence, we propose a broadband achromatic metalens integrated on the end face of a single-mode fiber covering the entire low-loss wavelength region. Utilizing the particle swarm optimization algorithm, we have substantially mitigated the phase-compensated matching error in the achromatic scheme. It demonstrates that the metalens is achievable with achromatic aberration and focuses over the entire low-loss wavelength band with a high mean focusing efficiency of 84.55%. Furthermore, this device exhibits a remarkable capability to break through the diffraction limit of the output field. This work provides a theoretical basis for fiber-integrated achromatic metalens over the entire low-loss bands, which has promising applications in imaging, sensing, and optical communication.
Trend and predictive psychosocial factors of persistent depression/non-depression in Chinese adolescents: A three-year longitudinal study
Authors: Liu Ming , Xie Fei , Dai Zongpei , Dai Qin , Chi Xin-li 
Published: October 2024

Background
Depressive symptoms are common in adolescents, while its prevalence trend in adolescents is seldom reported. In addition, few studies focus on adolescents without depressive symptoms. This study aimed to reveal the trend and predictors of persistent depression/non-depression among Chinese adolescents over three-year period.

Methods
Three-wave data were collected from T1 to T3 in a sample from six junior high schools in Shenzhen, China. The 20-item of Center for Epidemiologic Studies Depression Scale was used, with scoring ≥16 as depression.

Results
Of all 1301 adolescents, 33.4%, 15.5% and 9.0% reported depressive symptoms at baseline, T2 and T3 respectively, while 66.6%, 47.7% and 39.6% reported non-depressive symptoms at three time-points. At the individual level, baseline positive identity and general positive youth development significantly increased persistent non-depression at T2 and T3. At the family level, baseline family harmony and communication consistently prevented persistent depression at T2 and T3, while family communication consistently promoted non-depression. At the school level, baseline awareness of no expectation from teacher and poor interpersonal relationship consistently increased persistent depression and prevented non-depression.

Conclusions
The incidence of depression in adolescents aged 11–15 is not high. The rate of persistent non-depression is approximately 30% higher than that of persistent depression, and both have a downward trend over years. Positive youth development and healthy family function are protective factors of depression, while school maladjustment decreases persistent non-depression. During early adolescence, more attention should be paid to family function and school maladjustment to promote non-depression in adolescents from a new broader view.