bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are long‐term widespread avian body size changes related to food availability? A test using contemporaneous changes in carotenoid‐based color
Authors: Little Roellen , Gardner Janet L. , Amano Tatsuya , Delhey Kaspar , Peters Anne 
Published: April 2017

AbstractRecent changes in global climate have been linked with changes in animal body size. While declines in body size are commonly explained as an adaptive thermoregulatory response to climate warming, many species do not decline in size, and alternative explanations for size change exist. One possibility is that temporal changes in animal body size are driven by changes in environmental productivity and food availability. This hypothesis is difficult to test due to the lack of suitable estimates that go back in time. Here, we use an alternative, indirect, approach and assess whether continent‐wide changes over the previous 100 years in body size in 15 species of Australian birds are associated with changes in their yellow carotenoid‐based plumage coloration. This type of coloration is strongly affected by food availability because birds cannot synthesize carotenoids and need to ingest them, and because color expression depends on general body condition. We found significant continent‐wide intraspecific temporal changes in body size (wing length) and yellow carotenoid‐based color (plumage reflectance) for half the species. Direction and magnitude of changes were highly variable among species. Meta‐analysis indicated that neither body size nor yellow plumage color showed a consistent temporal trend and that changes in color were not correlated with changes in size over the past 100 years. We conclude that our data provide no evidence that broad‐scale variation in food availability is a general explanation for continent‐wide changes in body size in this group of species. The interspecific variability in temporal changes in size as well as color suggests that it might be unlikely that a single factor drives these changes, and more detailed studies of museum specimens and long‐term field studies are required to disentangle the processes involved.
Context‐dependent resistance of freshwater invertebrate communities to drying
Authors: Datry Thibault , Vander Vorste Ross , Goïtia Edgar , Moya Nabor , Campero Melina , Rodriguez Fabiola , Zubieta Jose , Oberdorff Thierry 
Published: April 2017

AbstractMore freshwater ecosystems are drying in response to global change thereby posing serious threat to freshwater biota and functions. The production of desiccation‐resistant forms is an important adaptation that helps maintain biodiversity in temporary freshwaters by buffering communities from drying, but its potential to mitigate the negative effects of drying in freshwater ecosystems could vary greatly across regions and ecosystem types. We explored this context dependency by quantifying the potential contribution of desiccation‐resistance forms to invertebrate community recovery across levels of regional drying prevalence (defined as the occurrence of drying events in freshwaters in a given region) and ecosystem types (lentic, lotic) in temporary neotropical freshwaters. We first predicted that regional drying prevalence influences the selection of species with desiccation‐resistant forms from the regional species pools and thus increases the ability of communities to recover from drying. Second, we predicted lentic freshwaters harbor higher proportions of species with desiccation‐resistant forms compared to lotic, in response to contrasted hydrologic connectivity. To test these predictions, we used natural experiments to quantify the contribution of desiccation‐resistant forms to benthic invertebrate community recovery in nine intermittent streams and six geographically isolated temporary wetlands from three Bolivian regions differing in drying prevalence. The contribution of desiccation‐resistant forms to community recovery was highest where regional drying prevalence was high, suggesting the species pool was adapted to regional disturbance regimes. The contribution of desiccation‐resistant forms to community recovery was lower in streams than in wetlands, emphasizing the importance of hydrologic connectivity and associated recolonization processes from in‐stream refuges to recovery in lotic systems. In all regions, the majority of functional traits were present in desiccation‐resistant taxa indicating this adaptation may help maintain ecosystem functions by buffering communities from the loss of functional traits. Accounting for regional context and hydrologic connectivity in community recovery processes following drying can help refine predictions of freshwater biodiversity response to global change.
The distribution, diversity, and conservation status of Cycas in China
Authors: Zheng Ying , Liu Jian , Feng Xiuyan , Gong Xun 
Published: April 2017

AbstractAs ancient gymnosperm and woody plants, cycads have survived through dramatic tectonic activities, climate fluctuation, and environmental variations making them of great significance in studying the origin and evolution of flora biodiversity. However, they are among the most threatened plant groups in the world. The principal aim of this review is to outline the distribution, diversity, and conservation status of Cycas in China and provide suggestions for conservation practices. In this review, we describe the taxonomy, distribution, and conservation status of Cycas in China. By comparing Chinese Cycas species with its relatives worldwide, we then discuss the current genetic diversity, genetic differentiation of Cycas, and try to disentangle the potential effects of Quaternary climate changes and topographical events on Cycas. We review conservation practices from both researchers and practitioners for these rare and endangered species. High genetic diversity at the species level and strong genetic differentiation within Cycas have been observed. Most Cycas species in southwest China have experienced population retreats in contrast to the coastal Cycas's expansion during the Quaternary glaciation. Additionally, human activities and habitat fragmentation have pushed these endangered taxa to the brink of extinction. Although numerous efforts have been made to mitigate threats to Cycas survival, implementation and compliance monitoring in protection zones are currently inadequate. We outline six proposals to strengthen conservation measures for Cycas in China and anticipate that these measures will provide guidelines for further research on population genetics as well as conservation biology of not only cycads but also other endangered species worldwide.
Variation in reach‐scale thalweg‐migration intensity in a braided reach of the lower Yellow River in 1986–2015
Authors: Li Jie , Xia Junqiang , Zhou Meirong , Deng Shanshan , Zhang Xiaolei 
Published: April 2017

AbstractThalweg migration of an alluvial river plays a key role in channel evolution, which may influence the effect of existing river training works and biodiversity on floodplains, and cause losses in riparian land and property. The braided reach of the Lower Yellow River underwent continuous channel aggradation during the period from 1986 to 1999, and then remarkable channel degradation in 1999–2015 owing to the state of operation of the Xiaolangdi Reservoir in 1999. Here we quantify associated thalweg migration changes and identify the key influencing factor in the braided reach. Thalweg‐migration distances and intensities at section‐ and reach‐scales were calculated during the past 30 years from 1986 to 2015, in order to investigate the characteristics of thalweg migration in the reach. There was a 47% reduction in the reach‐scale thalweg‐migration distance and a 35% reduction in the corresponding migration intensity after the reservoir operation. It is also revealed that fluvial erosion intensity is a dominant factor in controlling the thalweg migration, based on the investigation into various influencing factors in the study reach. The thalweg‐migration intensity of the braided reach can be expressed as a power function of the previous four‐year average fluvial erosion intensity. The calculated thalweg‐migration intensities in 1986–2015 using the proposed relation generally agree with the observed data. Copyright © 2017 John Wiley & Sons, Ltd.
Structural and thermal controls of rockfall frequency and magnitude within rockwall–talus systems (Swiss Alps)
Authors: Messenzehl Karoline , Dikau Richard 
Published: April 2017

AbstractBoth from a systemic and natural hazard perspective, it is essential to understand the causes and frequency of rockfalls in mountain terrain and to predict the block sizes deposited at specific locations. Commonly, rockfalls are studied either retrospectively, using talus slopes, or directly by rockwall surveys. Nevertheless, our understanding of rockfall activity, particularly at the lower magnitude spectrum, is still incomplete. Moreover, the explanatory framework is rarely addressed explicitly. In this study, we investigate two rockwall–talus systems in the Swiss Alps to estimate the rockfall frequency–magnitude pattern and their key controls. We present a holistic approach that integrates deductive geotechnical and thermal investigations of the source rockwalls with abductive talus‐based explanations of rockfall volume and frequency.The rockwalls' three‐dimensional (3D) joint pattern indicates that 75% of the blocks may be released as debris fall (< 14 m3) and boulder falls (14–61 m3), which is mirrored in the corresponding talus material. Using two‐year records of near‐surface rockwall temperatures as input for a 1D heat conduction model underlines the destabilizing role of seasonal ice segregation. Deepest frost cracking of 300 cm may occur on the north‐northeast (NNE)‐exposed, snow‐rich rockwall, with peaks at the outermost surface. The synthesis of all data suggests that infrequent, large planar slides (approximately every 250 years) overlain by smaller, more frequent wedge and toppling failures (approximately every 17–50 years) as well as high‐frequency flake‐like clasts (3–6 events/year) characterize the rockfall frequency–magnitude pattern at Hungerli Peak.Here, we argue that small‐size rockfalls need more scientific attention, particularly in discontinuous permafrost zones. Our study emphasizes that future frequency–magnitude research should ideally incorporate site‐specific structural and thermal properties, rather than just focusing on climatic or meteorological triggers. We discuss how holistic rockwall–talus approaches, as proposed here, could help to increase our process understanding of rockfalls in mountain environments. Copyright © 2017 John Wiley & Sons, Ltd.
Assessment of connectivity in a water‐stressed wetland (Kaabar Tal) of Kosi‐Gandak interfan, north Bihar Plains, India
Authors: Singh Manudeo , Tandon Sampat K. , Sinha Rajiv 
Published: April 2017

AbstractLandscape elements respond to the processes acting on them, and this response connects with neighboring landscape units. The propagation, superposition, and interference of these responses are functions of the connectivity among the landscape units. Such landscape units are referred to as ‘Connectivity Response Units’ or CRUs that are in turn influenced by topography and landuse/landcover (LULC). The CRUs are obtained by the application of diffusion‐kernel based smoothing technique over the connectivity potential maps. A framework has been designed using the CRUs to understand the impacts of changing LULC on the connectivity structure in a relatively flat terrain under pre‐ and post‐monsoon scenarios. The proposed framework has been applied to a water‐stressed wetland occurring in an interfan setting in north Bihar plains, eastern India. It has also been demonstrated that CRUs can be used as a viable option for understanding the seasonal and temporal dynamics of connectivity structure in and around such wetlands and for guiding a rehabilitation strategy for such fragile ecosystems. Copyright © 2017 John Wiley & Sons, Ltd.
Stent‐mediated gene and drug delivery for cardiovascular disease and cancer: A brief insight
Authors: Krishnagopal Akshaya , Reddy Aakash , Sen Dwaipayan 
Published: April 2017

AbstractThis review concisely recapitulates the different existing modes of stent‐mediated gene/drug delivery, their considerable advancement in clinical trials and a rationale for other merging new technologies such as nanotechnology and microRNA‐based therapeutics, in addition to addressing the limitations in each of these perpetual stent platforms. Over the past decade, stent‐mediated gene/drug delivery has materialized as a hopeful alternative for cardiovascular disease and cancer in contrast to routine conventional treatment modalities. Regardless of the phenomenal recent developments achieved by coronary interventions and cancer therapies that employ gene and drug‐eluting stents, practical hurdles still remain a challenge. The present review highlights the limitations that each of the existing stent‐based gene/drug delivery system encompasses and therefore provides a vision for the future with respect to discovering an ideal stent therapeutic platform that would circumvent all the practical hurdles witnessed with the existing technology. Further study of the improvisation of next‐generation drug‐eluting stents has helped to overcome the issue of restenosis to some extent. However, current stent formulations fall short of the anticipated clinically meaningful outcomes and there is an explicit need for more randomized trials aiming to further evaluate stent platforms in favour of enhanced safety and clinical value. Gene‐eluting stents may hold promise in contributing new ideas for stent‐based prevention of in‐stent restenosis through genetic interventions by capitalizing on a wide variety of molecular targets. Therefore, the central consideration directs us toward finding an ideal stent therapeutic platform that would tackle all of the gaps in the existing technology.
Changes in chondrolabral mechanics, coverage, and congruency following peri‐acetabular osteotomy for treatment of acetabular retroversion: A patient‐specific finite element study
Authors: Knight Spencer J. , Abraham Christine L. , Peters Christopher L. , Weiss Jeffrey A. , Anderson Andrew E. 
Published: April 2017

ABSTRACTUsing a validated finite element (FE) protocol, we quantified cartilage and labrum mechanics, congruency, and femoral coverage in five male patients before and after they were treated for acetabular retroversion with peri‐acetabular osteotomy (PAO). Three‐dimensional models of bone, cartilage, and labrum were generated from computed tomography (CT) arthrography images, acquired before and after PAO. Walking, stair‐ascent, stair‐descent, and rising from a chair were simulated. Cartilage and labrum contact stress, contact area, and femoral coverage were calculated overall and regionally. Mean congruency (average of local congruency values for FE nodes in contact) and peak congruency (most incongruent node in contact) were calculated overall and regionally. Load supported by the labrum was represented as a raw change in the ratio of the applied force transferred through the labrum and percent change following surgery (calculated overall only). Considering all activities, following PAO, mean acetabular cartilage contact stress increased medially, superiorly, and posteriorly; peak stress increased medially and posteriorly. Peak labrum stresses decreased overall and superiorly. Acetabular contact area decreased overall and laterally, and increased medially. Labral contact area decreased overall, but not regionally. Load to the labrum decreased. Femoral head coverage increased overall, anterolaterally, and posterolaterally, but decreased anteromedially. Mean congruency indicated the hip became less congruent overall, anteriorly, and posteriorly; peak congruency indicated a less congruent joint posteriorly. Clinical relevance: Medialization of contact and reductions in labral loading following PAO may prevent osteoarthritis, but this procedure increases cartilage stresses, decreases contact area, and makes the hip less congruent, which may overload cartilage. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2567–2576, 2017.
Percutaneous Epiphysiodesis Using Transphyseal Screws: A Case Series Demonstrating High Efficacy
Authors: Dodwell Emily R. , Garner Matthew R. , Bixby Elise , Luderowski Eva M. , Green Daniel W. , Blanco John S. , Widmann Roger F. 
Published: April 2017

Background Percutaneous epiphysiodesis using transphyseal screws (PETS) has been associated with implant failure, implant prominence, angular deformities, and delayed growth inhibition. Questions/Purposes The aim of this study was to assess the complication rate and efficacy (defined as actual growth inhibition divided by expected growth inhibition) of PETS and to identify factors associated with improved efficacy. Methods Patients who underwent distal femoral and/or proximal tibial PETS between January 2007 and June 2014 were identified. Complications, efficacy, and final limb-length discrepancy (LLD) were calculated using multipliers and inhibition rates based on previous growth. Associations between efficacy and screw insertion angle (SIA), body mass index, and number of threads crossing the physis were calculated. Results Eight-two patients (126 treated physes) were included. The mean pre-operative LLD was 27.7 mm (SD = 7.5). Following epiphysiodesis, 15 had temporary pain (18%), five had temporary effusion (6.1%), four had broken implants (4.9%), four developed mild angulation (4.9%), and three had failed epiphysiodesis requiring revision (3.7%). Thirty-one underwent screw removal ( n = 31, 38%). Mean LLD at maturity was 17.3 mm (SD = 5.8 mm). Mean efficacy at the distal femur was 97% (SD = 46%), at the proximal tibia was 108% (SD = 66%) and was 103% (SD = 57%) overall. Increased screw threads across the lateral proximal tibial physis (Spearman's correlation coefficient = 0.67; 95% CI = 0.40–0.94) and higher BMI (Spearman's correlation coefficient = 0.55; 95% CI = 0.34–0.77) were positively associated with increased efficacy. Conclusions The efficacy of PETS may be more favorable than previously reported. Only 3.7% had serious complications requiring revision epiphysiodesis, lower than previous reports. Attention to sufficient screw threads across the physis may be important in optimizing PETS results.
Fever after peripheral blood stem cell infusion in haploidentical transplantation with post-transplant cyclophosphamide
Authors: Arango Marcos , Combariza Juan F. 
Published: April 2017

Objective/background:
Noninfection-related fever can occur after peripheral blood stem cell infusion in haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide. The objective of this study was to analyze the incidence of fever and characterize some clinical features of affected patients.

Methods:
A retrospective case-series study with 40 patients who received haploidentical hematopoietic stem cell transplantation was carried out.

Results:
Thirty-three patients (82.5%) developed fever; no baseline characteristic was associated with its development. Median time to fever onset was 25.5 h (range, 9.5–100 h) and median peak temperature was 39.0 °C (range, 38.1–40.5 °C). Not a single patient developed hemodynamic or respiratory compromise that required admission to the intensive care unit. Fever was not explained by infection in any case. Ninety-one percent of the febrile episodes resolved within 96 h of cyclophosphamide administration. No significant difference in overall survival, event-free survival, or graft versus host disease-free/relapse-free survival was found in the group of febrile individuals after peripheral blood stem cell infusion.

Conclusion:
Fever after peripheral blood stem cell infusion in this clinical setting was common; it usually subsides with cyclophosphamide administration. The development of fever was not associated with an adverse prognosis.
Analysis of expression of transcription factors in early human retina
Authors: Chen Jing , Ma Lixiang , Wang Songtao , Wang Xiaobing , Sun Yan , Gao Lu , Li Jin , Zhou Guomin 
Published: April 2017

AbstractThe retina originates in the central nervous system. Due to its accessibility and simplicity, the retina has become an invaluable model for studying the basic mechanisms involved in development. To date, considerable knowledge regarding the interactions among genes that coordinate retinal development has been gained from extensive research in model animals. However, our understanding of retinal development in humans remains undeveloped. Here, we analyze the expression of transcription factors that are involved in the early development of the retina in human embryos at 6–12 weeks post‐conception. Our work demonstrates that early developing neural retinas can be divided into two layers, the outer and inner neuroblast layers. Eye‐field transcription factors and those related to the early development of the retina have distinct expression patterns in the two layers. Cell‐type‐specific transcription factors emerge at 8 weeks. These data provide clear and systemic structures for early retinal development in human.
A Southern View on the Tuareg Rebellions in Mali
Authors: Kone Kassim 
Published: April 2017

Abstract:Since Mali’s independence in 1960, the Tuareg, a minority ethnic group, have staged successive rebellions, with the major ones occurring in 1963, 1990, 2006, and 2012. While discussions of “the Tuareg issue” have sometimes led both the Malian and the international press, as well as scholars, to make inaccurate generalizations, it is true that almost all the armed conflicts of the past fifty years in Mali were originated by people of the Tuareg group. Therefore, many of their Malian compatriots hold the Tuareg people responsible for the destruction of life and human rights violations that have taken place since the beginning of 2012. This article focuses on the events of 2012 and their aftermath and explores some social, cultural, and political differences between northern Tuareg and southern Bamana peoples in particular. It asks two specific questions: Is there something about Tuareg society, culture, and politics (i.e., Tuareg identity) that causes an incompatibility with the Mali Republic? And if not, where has the Malian government failed through the successive regimes since independence?
Global Media and Local Verbal Art Representations of Northern Malian Tuareg
Authors: Rasmussen Susan J. 
Published: April 2017

Abstract:This article offers a critique of widely disseminated portrayals of northern Malian Tuareg by outside media, which tend to portray all Tuareg as warriors and criminals and to project pseudo-scientific concepts of “race” onto relationships between Tuareg and other Malians, recalling the now discredited colonial “Hamitic Myth” in Rwanda. It also analyzes local oral historical accounts that present themes of Mali as both a protected fortress and welcoming crossroads, a country that both resists and absorbs intruders, and that also express concepts of identity based on language, culture, and flexible social affiliation. The article is based partly on interviews with internationally known local musicians who function as mediating “third voices,” and concludes with a discussion of wider implications of these findings for notions of voice, authority, and the mutual construction of ideas of Africa.
Political Participation and Mobilization after Mali’s 2012 Coup
Authors: Whitehouse Bruce 
Published: April 2017

Abstract:If the sudden downfall of Mali’s officially democratic system in early 2012 surprised many observers, the failings of the Malian state—including public disaffection with the political process, weak rule of law, and inadequate delivery of basic services—were widely known both at home and abroad. Focusing on activists based in Bamako, this article assesses Malian civil society’s response to these challenges since the March 2012 military coup and considers prospects for wider political engagement by the Malian public.