bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainability in multi‐tier supply chains: Understanding the double agency role of the first‐tier supplier
Authors: Wilhelm Miriam M. , Blome Constantin , Bhakoo Vikram , Paulraj Antony 
Published: December 2015

AbstractIn light of the growing complexity of globally dispersed, multi‐tier supply chains, the involvement of first‐tier suppliers has become instrumental in the quest for achieving sustainability compliance along the supply chain. We describe this new responsibility as the double agency role. We employ agency and institutional theory arguments to explore the conditions under which first‐tier suppliers will act as agents who fulfill the lead firm's sustainability requirements (i.e., the primary agency role) and implement these requirements in their suppliers' operations (i.e., the secondary agency role). The findings from three in‐depth case studies embedded in different institutional contexts highlight the importance for lead firms to incentivize each agency role separately and to reduce information asymmetries, particularly at the second‐tier level. In addition, our inductive analysis reveals several contingency factors that influence the coupling of the secondary agency role of the first‐tier supplier. These factors include resource availability at the first‐tier supplier's firm, the lead firm's focus on the triple‐bottom‐line dimension (i.e., environmental or social), the lead firm's use of power, and the lead firm's internal alignment of the sustainability and purchasing function. We integrate our findings in a conceptual framework that advances the research agenda on multi‐tier sustainable supply chains, and we subsequently outline the practical implications of assigning the double agency role to first tier suppliers.
Stylistic contrast and narrative function inCogad Gáedel re Gallaib
Authors: Downham Clare 
Published: December 2015

AbstractThe Battle of Clontarf was fought in A.D. 1014 by the forces of Brian Boru, over-king of Munster, and his allies against the forces of Viking Dublin, Leinster and their foreign allies. The saga ‘The War of the Irish and the Foreigners’(Cogad Gáedel re Gallaib)was written about events leading up the conflict and gives a dramatic account of events on the battlefield. It became the archetype for many later legends about Clontarf. This paper explores stylistic contrast in thesagabetween the terse description of events in the early Viking Age and the florid account of the reign of Brian Boru. This contrast has led some readers to conclude that two separate narratives were conflated inCogad Gáedel re Gallaib– the first being a summary of annals and the second being a saga. However this paper argues that there is a unity of purpose throughout the work and that its stylistic divisions were deliberately contrived to help glorify Brian’s victory at the Battle of Clontarf.
Life, Luck, and How I Became a Historian
Authors: Socolow Susan M. 
Published: December 2015

Before I begin, I want to thank the Conference on Latin American History [CLAH] and the Distinguished Service Award Committee for giving me this signal honor. This organization has always been important to me, and it's really nice to know tiiat it thinks I've been important to it.
The last talk I gave to CLAH was in Atlanta five years ago. I told the story of one man, Santiago de Liniers, and his good and bad fortune. Just as for Liniers, luck has played a huge role in my life.
Portuguese Migration to Rio de Janeiro, 1822-1850
Authors: Nunes Rosana Barbosa 
Published: December 2015

During the period between the Brazilian declaration of independence from Portugal in 1822 and Brazil's abolition of the slave trade in 1850, Rio de Janeiro constituted the most important destination of Portuguese emigrants in the world. In 1841, the preponderance of these immigrants in that city was described by a representative of the Portuguese government in Rio, Ildefonso Leopoldo Bayard:In the shops in Rio de Janeiro you find that the majority of the clerks are Portuguese, … in theengenhosthe Portuguese are the administrators and the slaves' overseers, in the residences they are the servants, and in the maritime work they are the ships' masters, and even the white fishermen.A number of factors made this city attractive to these migrants. The arrival of the Portuguese court and the opening of the city's port to foreign trade and foreign merchants, created an economic boom in Rio de Janeiro in the early nineteenth century. This growth was also perpetuated by the increasing coffee economy after the 1830s.
Local cohomology modules of invariant rings
Authors: PUTHENPURAKAL TONY J. 
Published: December 2015

AbstractLetKbe a field and letRbe a regular domain containingK. LetGbe a finite subgroup of the group of automorphisms ofR. We assume that |G| is invertible inK. LetRGbe the ring of invariants ofG. LetIbe an ideal inRG. Fixi⩾ 0. IfRGis Gorenstein then:(i)injdimRGHiI(RG) ⩽ dim SuppHiI(RG);(ii)$H^j_{\mathfrak{m}}$(HiI(RG)) is injective, where$\mathfrak{m}$is any maximal ideal ofRG;(iii)μj(P, HiI(RG)) =μj(P′,HiIR(R)) whereP′ is any prime inRlying aboveP.We also prove that ifPis a prime ideal inRGwithRGPnot Gorensteinthen either the bass numbersμj(P, HiI(RG)) is zero for alljor there existscsuch thatμj(P, HiI(RG)) = 0 forj<candμj(P, HiI(RG)) > 0 for allj⩾c.
Double theta polynomials and equivariant Giambelli formulas
Authors: TAMVAKIS HARRY , WILSON ELIZABETH 
Published: December 2015

AbstractWe use Young's raising operators to introduce and studydouble theta polynomials, which specialize to both the theta polynomials of Buch, Kresch, and Tamvakis, and to double (or factorial) SchurS-polynomials andQ-polynomials. These double theta polynomials give Giambelli formulas which represent the equivariant Schubert classes in the torus-equivariant cohomology ring of symplectic Grassmannians, and we employ them to obtain a new presentation of this ring in terms of intrinsic generators and relations.
Sperm dilution ratio affects post-thaw motility rate and velocity of Prochilodus lineatus (Characiformes) sperm
Authors: Viveiros Ana T.M. , Leal Marcelo C. 
Published: December 2015

SummaryThere is a lack of standardization in sperm cryopreservation of aquatic organisms and, thus, a necessity of more accurate investigations in all steps of this process. In this study, the effects of sperm dilution ratio on post-thaw sperm quality of Prochilodus lineatus were evaluated. Sperm was diluted in a standard freezing medium (glucose and methyl glycol) at four different ratios (sperm to final volume = 1:5, 1:10, 1:50 or 1:100), frozen in a nitrogen vapour vessel at –170°C and then stored in liquid nitrogen vessel at –196°C. Post-thaw motility rate and velocities (curvilinear = VCL; average path = VAP; straight line = VSL) were determined using a Computer-Assisted Sperm Analyzer (CASA) at 10 and 40 s post-activation. The highest motility rates were observed when sperm was frozen at a ratio of 1:5 (76%) and 1:10 (75%). The highest VCL (225 μm/s) and VAP (203 μm/s) were observed at a ratio of 1:10, while VSL was similar among samples frozen at 1:5, 1:10 and 1:50 (97–124 μm/s). When those parameters were evaluated again 30 s later, motility decreased significantly in samples frozen at a ratio of 1:5 (57%) and 1:10 (61%), while velocities decreased significantly in all samples regardless of dilution ratio (75–85 μm/s of VCL, 38–53 μm/s of VAP and 25–39 μm/s of VSL). P. lineatus sperm should be frozen at a ratio of 1:10, where both the number of loaded sperm per straw and the post-thaw quality are maximized.
The ‘Last’ Friendship Exchanges between Siam and Vietnam, 1879–1882: Siam between Vietnam and France—and Beyond
Authors: Koizumi Junko 
Published: December 2015

AbstractStudies of Siam's diplomatic relations from the mid-nineteenth century have been focussed on its troubled relations with Western colonial powers, often within a bilateral framework. While highlighting issues such as territorial losses and treaty revisions, scholarly interest tends to have overlooked Siam's relations with its neighbouring countries. Based on archival records at the National Archives of Thailand, this article aims to fill this gap by examining diplomatic exchanges between the Siamese and Vietnamese courts that took place between 1879 and 1882. In April 1879, a royal mission from the Vietnamese court bearing gifts and a royal letter from Tự Đức to Chulalongkorn arrived in Bangkok. It was allegedly the first formal mission from the Vietnamese court in almost half a century after the two countries had come into conflict in the 1830s. By examining how Siam and Vietnam sought to maintain and manipulate ‘traditional’ interstate relations in the face of treaty arrangements that France enforced upon Vietnam, this article reveals complex issues involved in the process of negotiations, such as the questions of maintaining the equality between the two monarchies and of the ‘translation’ of the concepts of sovereignty between Thai and Sino-Vietnamese languages, and suggests the necessity to pay more attention to historical and broader regional contexts in Asia.
Persönliche vs. computerbasierte Alkoholintervention für Krankenhauspatienten: Studiendesign
Authors: Freyer-Adam Jennis , Baumann Sophie , Schnuerer Inga , Haberecht Katja , John Ulrich , Gaertner Beate 
Published: December 2015

Zusammenfassung. Ziel: Persönliche Beratungen können bei stationären Krankenhauspatienten Alkoholkonsum und Mortalität reduzieren. Sie sind jedoch mit hohen Kosten verbunden, wenn aus Public-Health-Erfordernis viele Menschen einer Bevölkerung erreicht werden müssen. Computerbasierte Interventionen stellen eine Alternative dar. Jedoch ist ihre Wirksamkeit im Vergleich zu persönlichen Beratungen und im Allgemeinkrankenhaus noch unklar. Eine quasi-randomisierte Kontrollgruppenstudie „Die Bedeutung der Vermittlungsform für Alkoholinterventionen bei Allgemeinkrankenhauspatienten: Persönlich vs. Computerisiert“ soll dies untersuchen. Design und Methoden werden beschrieben. Methode: Über 18 Monate sind alle 18- bis 64-jährigen Patienten auf Stationen der Universitätsmedizin Greifswald mittels Alcohol Use Disorder Identification Test (AUDIT) zu screenen. Frauen/Männer mit AUDIT-Consumption ≥ 4/5 und AUDIT < 20 werden einer von drei Gruppen zugeordnet: persönliche Intervention (Beratungen zur Konsumreduktion), computerbasierte Intervention (individualisierte Rückmeldebriefe und Broschüren) und Kontrollgruppe. Beide Interventionen erfolgen im Krankenhaus sowie telefonisch bzw. postalisch nach 1 und 3 Monaten. In computergestützten Telefoninterviews nach 6, 12, 18 und 24 Monaten wird Alkoholkonsum erfragt. Schlussfolgerung: Das Studienvorhaben, sofern erfolgreich umgesetzt, ist geeignet die längerfristige Wirksamkeit einer persönlichen und computerbasierten Intervention im Vergleich zu untersuchen.
Moderators of Outcome in a Web-Based Substance Use Intervention for Adolescents
Authors: Arnaud Nicolas , Baldus Christiane , Elgán Tobias H. , Tønnesen Hanne , Paepe Nina De , Csemy Ladislav , Thomasius Rainer 
Published: December 2015

Abstract. Aims: In this article we explore the moderators of effectiveness of WISEteens (Web-based brief Intervention for SubstancE using teens), a fully automated web-based brief motivational intervention targeting risky substance use among adolescents. Based on previous studies, we examined the differential effects on drinking of sex, readiness to change, self-efficacy, alcohol risk status, and parental monitoring as hypothesized moderators. Methods: We analyzed completers data from a two-armed RCT study with follow-up assessment after 3 months, including N = 211 self-enrolled adolescents (16 – 18 years) who screened positive for at-risk substance use in Sweden, Belgium, the Czech Republic, and Germany. The trial compared a single-session brief motivational intervention to an assessment-only control group with AUDIT-C scores for drinking frequency, quantity, and frequency of binge drinking in the past month as study outcome. Results: The analyses revealed a statistically significant moderation effect for sex on drinking in the previous month, with a stronger effect for males. In contrast, readiness to change, self-efficacy, alcohol risk status, and parental monitoring did not moderate the effects. Conclusions: Although the trial was limited by large dropout, our findings imply that web-based interventions can be particularly effective for male adolescents, although the effects of WISEteens were largely independent of other individual characteristics. Web-based brief intervention should integrate gender-specific components to raise effectiveness for females.
Polyoxometalate-based homochiral metal-organic frameworks for tandem asymmetric transformation of cyclic carbonates from olefins
Authors: Han Qiuxia , Qi Bo , Ren Weimin , He Cheng , Niu Jingyang , Duan Chunying 
Published: December 2015

AbstractCurrently, great interest is focused on developing auto-tandem catalytic reactions; a substrate is catalytically transferred through mechanistically distinct reactions without altering any reaction conditions. Here by incorporating a pyrrolidine moiety as a chiral organocatalyst and a polyoxometalate as an oxidation catalyst, a powerful approach is devised to achieve a tandem catalyst for the efficient conversion of CO2 into value-added enantiomerically pure cyclic carbonates. The multi-catalytic sites are orderly distributed and spatially matched in the framework. The captured CO2 molecules are synergistically fixed and activated by well-positioned pyrrolidine and amine groups, providing further compatibility with the terminal W=O activated epoxidation intermediate and driving the tandem catalytic process in a single workup stage and an asymmetric fashion. The structural simplicity of the building blocks and the use of inexpensive and readily available chemical reagents render this approach highly promising for the development of practical homochiral materials for CO2 conversion.
Selenium isotope evidence for progressive oxidation of the Neoproterozoic biosphere
Authors: Pogge von Strandmann Philip A. E. , Stüeken Eva E. , Elliott Tim , Poulton Simon W. , Dehler Carol M. , Canfield Don E. , Catling David C. 
Published: December 2015

AbstractNeoproterozoic (1,000–542 Myr ago) Earth experienced profound environmental change, including ‘snowball’ glaciations, oxygenation and the appearance of animals. However, an integrated understanding of these events remains elusive, partly because proxies that track subtle oceanic or atmospheric redox trends are lacking. Here we utilize selenium (Se) isotopes as a tracer of Earth redox conditions. We find temporal trends towards lower δ82/76Se values in shales before and after all Neoproterozoic glaciations, which we interpret as incomplete reduction of Se oxyanions. Trends suggest that deep-ocean Se oxyanion concentrations increased because of progressive atmospheric and deep-ocean oxidation. Immediately after the Marinoan glaciation, higher δ82/76Se values superpose the general decline. This may indicate less oxic conditions with lower availability of oxyanions or increased bioproductivity along continental margins that captured heavy seawater δ82/76Se into buried organics. Overall, increased ocean oxidation and atmospheric O2 extended over at least 100 million years, setting the stage for early animal evolution.
ChIP-seq reveals broad roles of SARD1 and CBP60g in regulating plant immunity
Authors: Sun Tongjun , Zhang Yaxi , Li Yan , Zhang Qian , Ding Yuli , Zhang Yuelin 
Published: December 2015

AbstractRecognition of pathogens by host plants leads to rapid transcriptional reprogramming and activation of defence responses. The expression of many defence regulators is induced in this process, but the mechanisms of how they are controlled transcriptionally are largely unknown. Here we use chromatin immunoprecipitation sequencing to show that the transcription factors SARD1 and CBP60g bind to the promoter regions of a large number of genes encoding key regulators of plant immunity. Among them are positive regulators of systemic immunity and signalling components for effector-triggered immunity and PAMP-triggered immunity, which is consistent with the critical roles of SARD1 and CBP60g in these processes. In addition, SARD1 and CBP60g target a number of genes encoding negative regulators of plant immunity, suggesting that they are also involved in negative feedback regulation of defence responses. Based on these findings we propose that SARD1 and CBP60g function as master regulators of plant immune responses.
AKAP9 regulates activation-induced retention of T lymphocytes at sites of inflammation
Authors: Herter Jan M. , Grabie Nir , Cullere Xavier , Azcutia Veronica , Rosetti Florencia , Bennett Paul , Herter-Sprie Grit S. , Elyaman Wassim , Luscinskas Francis W. , Lichtman Andrew H. , Mayadas Tanya N. 
Published: December 2015

AbstractThe mechanisms driving T cell homing to lymph nodes and migration to tissue are well described but little is known about factors that affect T cell egress from tissues. Here, we generate mice with a T cell-specific deletion of the scaffold protein A kinase anchoring protein 9 (AKAP9) and use models of inflammatory disease to demonstrate that AKAP9 is dispensable for T cell priming and migration into tissues and lymph nodes, but is required for T cell retention in tissues. AKAP9 deficiency results in increased T cell egress to draining lymph nodes, which is associated with impaired T cell re-activation in tissues and protection from organ damage. AKAP9-deficient T cells exhibit reduced microtubule-dependent recycling of TCRs back to the cell surface and this affects antigen-dependent activation, primarily by non-classical antigen-presenting cells. Thus, AKAP9-dependent TCR trafficking drives efficient T cell re-activation and extends their retention at sites of inflammation with implications for disease pathogenesis.
A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51
Authors: Ameziane Najim , May Patrick , Haitjema Anneke , van de Vrugt Henri J. , van Rossum-Fikkert Sari E. , Ristic Dejan , Williams Gareth J. , Balk Jesper , Rockx Davy , Li Hong , Rooimans Martin A. , Oostra Anneke B. , Velleuer Eunike , Dietrich Ralf , Bleijerveld Onno B. , Maarten Altelaar A. F. , Meijers-Heijboer Hanne , Joenje Hans , Glusman Gustavo , Roach Jared , Hood Leroy , Galas David , Wyman Claire , Balling Rudi , den Dunnen Johan , de Winter Johan P. , Kanaar Roland , Gelinas Richard , Dorsman Josephine C. 
Published: December 2015

AbstractFanconi anaemia (FA) is a hereditary disease featuring hypersensitivity to DNA cross-linker-induced chromosomal instability in association with developmental abnormalities, bone marrow failure and a strong predisposition to cancer. A total of 17 FA disease genes have been reported, all of which act in a recessive mode of inheritance. Here we report on a de novo g.41022153G>A; p.Ala293Thr (NM_002875) missense mutation in one allele of the homologous recombination DNA repair gene RAD51 in an FA-like patient. This heterozygous mutation causes a novel FA subtype, ‘FA-R’, which appears to be the first subtype of FA caused by a dominant-negative mutation. The patient, who features microcephaly and mental retardation, has reached adulthood without the typical bone marrow failure and paediatric cancers. Together with the recent reports on RAD51-associated congenital mirror movement disorders, our results point to an important role for RAD51-mediated homologous recombination in neurodevelopment, in addition to DNA repair and cancer susceptibility.
Prion protein localizes at the ciliary base during neural and cardiovascular development and its depletion affects α-tubulin post-translational modifications
Authors: Halliez Sophie , Martin-Lannerée Séverine , Passet Bruno , Hernandez-Rapp Julia , Castille Johan , Urien Céline , Chat Sophie , Laude Hubert , Vilotte Jean-Luc , Mouillet-Richard Sophie , Béringue Vincent 
Published: December 2015

AbstractAlthough conversion of the cellular form of the prion protein (PrPC) into a misfolded isoform is the underlying cause of prion diseases, understanding PrPC physiological functions has remained challenging. PrPC depletion or overexpression alters the proliferation and differentiation properties of various types of stem and progenitor cells in vitro by unknown mechanisms. Such involvement remains uncertain in vivo in the absence of any drastic phenotype of mice lacking PrPC. Here, we report PrPC enrichment at the base of the primary cilium in stem and progenitor cells from the central nervous system and cardiovascular system of developing mouse embryos. PrPC depletion in a neuroepithelial cell line dramatically altered key cilium-dependent processes, such as Sonic hedgehog signalling and α-tubulin post-translational modifications. These processes were also affected over a limited time window in PrPC–ablated embryos. Thus, our study reveals PrPC as a potential actor in the developmental regulation of microtubule dynamics and ciliary functions.
Mapping Chemical Selection Pathways for Designing Multicomponent Alloys: an informatics framework for materials design
Authors: Srinivasan Srikant , Broderick Scott R. , Zhang Ruifeng , Mishra Amrita , Sinnott Susan B. , Saxena Surendra K. , LeBeau James M. , Rajan Krishna 
Published: December 2015

AbstractA data driven methodology is developed for tracking the collective influence of the multiple attributes of alloying elements on both thermodynamic and mechanical properties of metal alloys. Cobalt-based superalloys are used as a template to demonstrate the approach. By mapping the high dimensional nature of the systematics of elemental data embedded in the periodic table into the form of a network graph, one can guide targeted first principles calculations that identify the influence of specific elements on phase stability, crystal structure and elastic properties. This provides a fundamentally new means to rapidly identify new stable alloy chemistries with enhanced high temperature properties. The resulting visualization scheme exhibits the grouping and proximity of elements based on their impact on the properties of intermetallic alloys. Unlike the periodic table however, the distance between neighboring elements uncovers relationships in a complex high dimensional information space that would not have been easily seen otherwise. The predictions of the methodology are found to be consistent with reported experimental and theoretical studies. The informatics based methodology presented in this study can be generalized to a framework for data analysis and knowledge discovery that can be applied to many material systems and recreated for different design objectives.
Construction of brain atlases based on a multi-center MRI dataset of 2020 Chinese adults
Authors: Liang Peipeng , Shi Lin , Chen Nan , Luo Yishan , Wang Xing , Liu Kai , Mok Vincent CT , Chu Winnie CW , Wang Defeng , Li Kuncheng 
Published: December 2015

AbstractDespite the known morphological differences (e.g., brain shape and size) in the brains of populations of different origins (e.g., age and race), the Chinese brain atlas is less studied. In the current study, we developed a statistical brain atlas based on a multi-center high quality magnetic resonance imaging (MRI) dataset of 2020 Chinese adults (18–76 years old). We constructed 12 Chinese brain atlas from the age 20 year to the age 75 at a 5 years interval. New Chinese brain standard space, coordinates and brain area labels were further defined. The new Chinese brain atlas was validated in brain registration and segmentation. It was found that, as contrast to the MNI152 template, the proposed Chinese atlas showed higher accuracy in hippocampus segmentation and relatively smaller shape deformations during registration. These results indicate that a population-specific time varying brain atlas may be more appropriate for studies involving Chinese populations.