bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond graft function impairment after liver transplantation: the prolonged cold ischemia time impact on recurrence of hepatocellular carcinoma after liver transplantation—a single-center retrospective study
Authors: Yu Jia , Yunhua Tang , Guo Yiwen , Dong Yuqi , Gong Jin long , Wang Tielong , Chen Zhitao , Chen Maogen , Ju Weiqiang , He Xiaoshun 
Published: October 2024

Purpose
Hepatocellular carcinoma (HCC) is one of the malignant tumors responsible for high mortality and recurrence rates. Although liver transplantation (LT) is an effective treatment option for HCC, ischemia-reperfusion injury (IRI) is a contributor to HCC recurrence after LT. Moreover, prolonged cold ischemia time (CIT) is a risk factor for IRI during LT, and there is insufficient clinical evidence regarding the impact of CIT on HCC recurrence after LT.

Patients and Methods
This retrospective study analyzed 420 patients who underwent LT for HCC between February 2015 and November 2020 at The First Affiliated Hospital, Sun Yat-sen University. The duration of CIT was defined as the time from clamping of the donor aorta until portal reperfusion.

Results
A total of 133 patients (31.7%) experienced tumor recurrence after LT, and CIT > 568 min was the independent risk factor for HCC recurrence (OR, 2.406; 95% CI [1.371–4.220]; p = 0.002). Multivariate Cox’s regression analysis revealed that the recipients’ gender, exceeding Milan criteria, poor differentiation, and alpha-fetoprotein (AFP) ≥400 ng/ml in CIT > 568 min group were independent risk factors for disease-free survival. The peak 7-day postoperative alanine aminotransferase (ALT) level (p < 0.001), the peak 7-day postoperative aspartate aminotransferase (AST) level (p < 0.001), the peak 7-day postoperative peak total bilirubin (TBIL) level (p = 0.012), and the incidence of early allograft dysfunction (EAD) (p = 0.006) were significantly higher in the CIT > 568 min group compared to the CIT ≤ 568 min group. Moreover, the amount of fresh frozen plasma (FFP) infusion during the operation increased (p = 0.02), and the time of mechanical ventilation postoperative was longer (p = 0.045).

Conclusion
An effective strategy to improve the prognosis is to reduce CIT; this strategy lowers the recurrence of HCC in patients undergoing LT, especially those within the Milan criteria.
Optimization of Groundnuts (Archis hypogeal) Yield through Response Surface Methodology
Authors: Kiprotich Dennis , Muriithi Dennis K. , Njogu Martin K. 
Published: October 2024

Groundnut production faces several constraints, including poor soil fertility, small land sizes, and inappropriate agricultural techniques. The study aimed to optimize groundnut (Archis hypogeal) yield using response surface methodology (RSM). It explored the use of CCD and RSM to determine the optimal application of rabbit, poultry, and sheep manure for maximum yield, a method not previously applied in groundnut production. The study was conducted at the Chuka University Teaching and Training Farm, Kairani. The experimental design was developed using Central Composite Design (CCD), with 20 experimental runs derived from 23 full factorial designs with six axial points and six center points. Data was collected on the weight of the groundnuts yield harvested in each experimental plot measured by use of a weighing scale. Response Surface Methodology techniques was adopted for data analysis in R-statistical software and R studio programing language. The study findings indicated that organic manures had a significant effect (P < 0.05) on the yield of groundnuts crop. The study revealed that application of 13.6097 t ha-1, 10.582 t ha-1 and 11.0814 t ha-1 of poultry, rabbit and sheep manure respectively are the optimum levels that would lead to maximum weight of groundnuts in the study area. The finding of this study could have an economic benefit to farmers in the study area which aligns with broader national goals of poverty reduction, rural development, and economic growth. This study recommended that farmers should adopt organic farming practices to reduce reliance on chemical fertilizers, improve soil health, and contribute to environmental sustainability.
Language Styles Used in Jete Indonesia and Doran Gadget’s article
Authors: Kezia Filippo Aurel 
Published: October 2024

This study aims to examine the language style used in an article of Jete Indonesia which is Five Best Jete Smartwatches to Accompany Your Activity, and Doran Gadget’s article which is GoPro Hero Twelve Specifications: Longer Battery Life!. The objective of the study is to analyze the different and similar language styles that were used in Jete Indonesia's article and Doran Gadget’s article. Besides, the writer employs a descriptive qualitative approach using Keraf’s (2010) theory on the types of language styles based on diction. The data analysis shows there is not a significant difference in the language styles used in Jete Indonesia’s article and Doran Gadget’s article. The research findings could be indicated by the vocabulary used in the formal and informal language styles from Jete Indonesia’s article and Doran Gadget’s article. Concerning the conversational style used between Jete Indonesia and Doran Gadget’s article, Doran Gadget which is a formal style employs the conversational style more than Jete Indonesia which is an informal one.
Modeling daily soil salinity dynamics in response to agricultural and environmental changes in coastal Bangladesh
Authors: Payo Andrés , Lázár Attila N. , Clarke Derek , Nicholls Robert J. , Bricheno Lucy , Mashfiqus Salehin , Haque Anisul 
Published: April 2017

AbstractUnderstanding the dynamics of salt movement in the soil is a prerequisite for devising appropriate management strategies for land productivity of coastal regions, especially low‐lying delta regions, which support many millions of farmers around the world. At present, there are no numerical models able to resolve soil salinity at regional scale and at daily time steps. In this research, we develop a novel holistic approach to simulate soil salinization comprising an emulator‐based soil salt and water balance calculated at daily time steps. The method is demonstrated for the agriculture areas of coastal Bangladesh (∼20,000 km2). This shows that we can reproduce the dynamics of soil salinity under multiple land uses, including rice crops, combined shrimp and rice farming, as well as non‐rice crops. The model also reproduced well the observed spatial soil salinity for the year 2009. Using this approach, we have projected the soil salinity for three different climate ensembles, including relative sea‐level rise for the year 2050. Projected soil salinity changes are significantly smaller than other reported projections. The results suggest that inter‐season weather variability is a key driver of salinization of agriculture soils at coastal Bangladesh.
Near‐vent chemical processes in a hydrothermal plume: Insights from an integrated study of the Endeavour segment
Authors: Coogan L. A. , Attar A. , Mihaly S. F. , Jeffries M , Pope M. 
Published: April 2017

AbstractThe Endeavour segment of the Juan de Fuca mid‐ocean ridge is one of the best studied ridge segments and has recently been instrumented as part of Ocean Networks Canada's NEPTUNE cabled observatory. Here we investigate the interaction between high‐temperature vent fluids and the overlying water column. A new tow‐yo survey found that the average temperature anomaly in the neutrally buoyant plume was ∼0.043°C. The water column temperature and light attenuation anomalies correlate linearly in some areas of the plume but in other areas there is a low light attenuation anomaly relative to the temperature anomaly. This temperature excess is interpreted to reflect heat input through (particle‐poor) diffuse flow. If this is correct, about half of the heat flux along the Endeavour segment comes from diffuse flow. Sediment trap and push core data show that the mass accumulation rate of the hydrothermal component of the sediments decreases rapidly with distance from the major vent fields. Large changes in the composition of the hydrothermal component of the sediments also occur with distance from the vent fields. The composition of the sediments indicates (i) sulfides precipitate early and accumulate most rapidly close to the vents with a preferential order of element removal from the plume of Cd > Ag > Cu > Co ∼ Fe; (ii) barite is deposited somewhat further from the vents. Strontium and Pb appear to be strongly incorporated in barite and/or other sulfate minerals; (iii) at most a few percent of the mass of these “insoluble” elements that is vented gets deposited within 1.5 km of the vents.
Shallow melting of MORB‐like mantle under hot continental lithosphere, Central Anatolia
Authors: Reid Mary R. , Schleiffarth W. Kirk , Cosca Michael A. , Delph Jonathan R. , Blichert‐Toft Janne , Cooper Kari M. 
Published: April 2017

AbstractWidespread mafic volcanism, elevated crustal temperatures, and plateau‐type topography in Central Anatolia, Turkey, could collectively be the result of lithospheric delamination, mantle upwelling, and tectonic escape. We use results from 40Ar/39Ar geochronology, basalt geochemistry, and a passive‐source broadband seismic experiment obtained in a collaborative international effort (Continental Dynamics‐Central Anatolia Tectonics) to investigate the upper mantle structure and evolution of melting conditions over an ∼2400 km2 area south and west of Hasan volcano. New 40Ar/39Ar dates for the basalts mostly cluster between 0.2 and 0.6 Ma, but some scoria cones are as old as 2.5 Ma. Basalts are dominantly Mg‐rich (Mg# = 62–71), moderately alkaline (normative Ne < 5 wt %), and, based on major and trace element signatures, derived from a peridotitic source. Covariations between radiogenic isotope and trace element signatures reveal contributions from a subduction‐related component and intraplate‐like mantle asthenosphere, as well as from ambient upper mantle. Central Anatolian basalts reflect maximum mantle potential temperatures of <1350°C and an average pressure of melt equilibration of 1.4 GPa, which are cooler and shallower than for basalts from Eastern and Western Anatolia. When considered in light of regionally slow upper mantle shear wave velocities, the mantle lithosphere may be thin and infiltrated by melts, or largely absent. An absence of secular changes in melting conditions suggests little to no lithospheric thinning over the past ∼1 Ma, despite evidence for lithospheric extension. Hasan basalts appear to be generated by decompression melting in response to the rollback of the Cyprean slab.
Miocene‐Recent sediment flux in the south‐central Alaskan fore‐arc basin governed by flat‐slab subduction
Authors: Finzel Emily S. , Enkelmann Eva 
Published: April 2017

AbstractThe Cook Inlet in south‐central Alaska contains the early Oligocene to Recent stratigraphic record of a fore‐arc basin adjacent to a shallowly subducting oceanic plateau. Our new measured stratigraphic sections and detrital zircon U‐Pb geochronology and Hf isotopes from Neogene strata and modern rivers illustrate the effects of flat‐slab subduction on the depositional environments, provenance, and subsidence in fore‐arc sedimentary systems. During the middle Miocene, fluvial systems emerged from the eastern, western, and northern margins of the basin. The axis of maximum subsidence was near the center of the basin, suggesting equal contributions from subsidence drivers on both margins. By the late Miocene, the axis of maximum subsidence had shifted westward and fluvial systems originating on the eastern margin of the basin above the flat‐slab traversed the entire width of the basin. These mud‐dominated systems reflect increased sediment flux from recycling of accretionary prism strata. Fluvial systems with headwaters above the flat‐slab region continued to cross the basin during Pliocene time, but a change to sandstone‐dominated strata with abundant volcanogenic grains signals a reactivation of the volcanic arc. The axis of maximum basin subsidence during late Miocene to Pliocene time is parallel to the strike of the subducting slab. Our data suggest that the character and strike‐orientation of the down‐going slab may provide a fundamental control on the nature of depositional systems, location of dominant provenance regions, and areas of maximum subsidence in fore‐arc basins.
Aluminum in zircon as evidence for peraluminous and metaluminous melts from the Hadean to present
Authors: Trail Dustin , Tailby Nicholas , Wang Yanling , Mark Harrison T. , Boehnke Patrick 
Published: April 2017

AbstractZircon structurally accommodates a range of trace impurities into its lattice, a feature which is used extensively to investigate the evolution of silicate magmas. One key compositional boundary of magmas is defined by whether the molar ratio of Al2O3/(CaO + Na2O + K2O) is larger or smaller than unity. Here we report ∼800 Al in zircon concentrations from 19 different rocks from the Lachlan Fold Belt (southeastern Australia), New England (USA), and Arunachal leucogranites (eastern Himalaya) with Al2O3/(CaO + Na2O + K2O) whole rock values that range from 0.88 to 1.6. Zircons from peraluminous rocks yield an average Al concentration of ∼10 ppm, which distinguishes them from crystals found in metaluminous rocks (∼1.3 ppm). This difference is related to the materials involved in the melting, assimilation, and/or magma differentiation processes; for example, magmas that assimilate Al‐rich material such as metapelites are expected to produce melts with elevated alumina activities, and thus zircons with high Al concentrations. These observations are applied to the Archean and Hadean Jack Hills detrital zircon record. Detrital Archean zircons, with ages from about 3.30 to 3.75 Ga, yield Al in zircon concentrations consistent with origins in peraluminous rocks in ∼8% of the cases (n = 236). A single zircon from the pre‐3.9 Ga age group (n = 39) contains elevated Al contents, which suggests that metaluminous crustal rocks were more common than peraluminous rocks in the Hadean. Weathered material assimilated into these Hadean source melts was not dominated by Al‐rich source material.
Productivity diagnosed from the diel cycle of particulate carbon in the North Pacific Subtropical Gyre
Authors: White Angelicque E. , Barone Benedetto , Letelier Ricardo M. , Karl David M. 
Published: April 2017

AbstractThe rate of primary production (PP) in the ocean is a critical ecosystem function that contributes to the regulation of air‐sea CO2 exchange. Historically, oceanographers have relied primarily on in vitro measurements of 14C uptake (14C‐PP) as a proxy for PP. Yet it can be difficult to reconcile PP rates measured in vitro with in situ rates such as those based on oxygen. Here we present diel cycles of optically derived particulate organic carbon (POC) measured in the North Pacific Subtropical Gyre. We have calculated gross production (OPTGP) from the daytime increase and nighttime decrease of optically derived POC, assuming that the observed change in POC represents the sum of PP and community losses. We have compared these estimates to parallel 14C‐PP incubations and considered sources of difference. We find that OPTGP is strongly related to 14C‐PP in this region and that growth and loss rates of POC are tightly coupled.
Thermo‐cryogenic controls of fracture kinematics in permafrost rockwalls
Authors: Draebing D. , Krautblatter M. , Hoffmann T. 
Published: April 2017

AbstractThermo‐cryogenic processes prepare and trigger rockfalls and rockslides in alpine environments. Temporal occurrence, controls, and applied stresses of Thermo‐cryogenic processes on rock masses are poorly understood. This paper reports annual crackmeter measurements with 3 h resolution across perennially ice‐filled fractures in an unstable rock permafrost crestline. Thermo‐cryogenic processes are controlled by snow cover onset and duration. Thermal changes in snow‐free periods control expansion and contraction coincident temperature gradients on a daily to seasonal scale. We can show how snow cover promotes sustained temperatures from −9 to −1°C and boosts ice segregation‐related fracture opening up to 1 cm in 8 months. During snowmelt, meltwater induces ice erosion and ice relaxation, which occur in the freeze‐thaw window close to the thawing point. We hypothesize that Thermo‐cryogenic processes and their cyclic repetition can lead to Thermo‐cryogenic fatigue preparing rock slope failure and can control type and location of rockfalls in a changing climate.
Role of internal variability in recent decadal to multidecadal tropical Pacific climate changes
Authors: Bordbar Mohammad Hadi , Martin Thomas , Latif Mojib , Park Wonsun 
Published: April 2017

AbstractWhile the Earth's surface has considerably warmed over the past two decades, the tropical Pacific has featured a cooling of sea surface temperatures in its eastern and central parts, which went along with an unprecedented strengthening of the equatorial trade winds, the surface component of the Pacific Walker Circulation (PWC). Previous studies show that this decadal trend in the trade winds is generally beyond the range of decadal trends simulated by climate models when forced by historical radiative forcing. There is still a debate on the origin of and the potential role that internal variability may have played in the recent decadal surface wind trend. Using a number of long control (unforced) integrations of global climate models and several observational data sets, we address the question as to whether the recent decadal to multidecadal trends are robustly classified as an unusual event or the persistent response to external forcing. The observed trends in the tropical Pacific surface climate are still within the range of the long‐term internal variability spanned by the models but represent an extreme realization of this variability. Thus, the recent observed decadal trends in the tropical Pacific, though highly unusual, could be of natural origin. We note that the long‐term trends in the selected PWC indices exhibit a large observational uncertainty, even hindering definitive statements about the sign of the trends.
On the role of ozone feedback in the ENSO amplitude response under global warming
Authors: Nowack Peer J. , Braesicke Peter , Luke Abraham N. , Pyle John A. 
Published: April 2017

AbstractThe El Niño–Southern Oscillation (ENSO) in the tropical Pacific Ocean is of key importance to global climate and weather. However, state‐of‐the‐art climate models still disagree on the ENSO's response under climate change. The potential role of atmospheric ozone changes in this context has not been explored before. Here we show that differences between typical model representations of ozone can have a first‐order impact on ENSO amplitude projections in climate sensitivity simulations. The vertical temperature gradient of the tropical middle‐to‐upper troposphere adjusts to ozone changes in the upper troposphere and lower stratosphere, modifying the Walker circulation and consequently tropical Pacific surface temperature gradients. We show that neglecting ozone changes thus results in a significant increase in the number of extreme ENSO events in our model. Climate modeling studies of the ENSO often neglect changes in ozone. We therefore highlight the need to understand better the coupling between ozone, the tropospheric circulation, and climate variability.
The effect of ring current electron scattering rates on magnetosphere‐ionosphere coupling
Authors: Perlongo N. J. , Ridley A. J. , Liemohn M. W. , Katus R. M. 
Published: April 2017

AbstractThis simulation study investigated the electrodynamic impact of varying descriptions of the diffuse aurora on the magnetosphere‐ionosphere (M‐I) system. Pitch angle diffusion caused by waves in the inner magnetosphere is the primary source term for the diffuse aurora, especially during storm time. The magnetic local time (MLT) and storm‐dependent electrodynamic impacts of the diffuse aurora were analyzed using a comparison between a new self‐consistent version of the Hot Electron Ion Drift Integrator with varying electron scattering rates and real geomagnetic storm events. The results were compared with Dst and hemispheric power indices, as well as auroral electron flux and cross‐track plasma velocity observations. It was found that changing the maximum lifetime of electrons in the ring current by 2–6 h can alter electric fields in the nightside ionosphere by up to 26%. The lifetime also strongly influenced the location of the aurora, but the model generally produced aurora equatorward of observations.
Effect of water on critical and subcritical fracture properties of Woodford shale
Authors: Chen Xiaofeng , Eichhubl Peter , Olson Jon E. 
Published: April 2017

AbstractSubcritical fracture behavior of shales under aqueous conditions is poorly characterized despite increased relevance to oil and gas resource development and seal integrity in waste disposal and subsurface carbon sequestration. We measured subcritical fracture properties of Woodford shale in ambient air, dry CO2 gas, and deionized water by using the double‐torsion method. Compared to tests in ambient air, the presence of water reduces fracture toughness by 50%, subcritical index by 77%, and shear modulus by 27% and increases inelastic deformation. Comparison between test specimens coated with a hydrophobic agent and uncoated specimens demonstrates that the interaction of water with the bulk rock results in the reduction of fracture toughness and enhanced plastic effects, while water‐rock interaction limited to the vicinity of the propagating fracture tip by a hydrophobic specimen coating lowers subcritical index and increases fracture velocity. The observed deviation of a rate‐dependent subcritical index from the power law K‐V relations for coated specimens tested in water is attributed to a time‐dependent weakening process resulting from the interaction between water and clays in the vicinity of the fracture tip.
North Atlantic storm driving of extreme wave heights in the North Sea
Authors: Bell R. J. , Gray S. L. , Jones O. P. 
Published: April 2017

AbstractThe relationship between storms and extreme ocean waves in the North Sea is assessed using a long‐period wave data set and storms identified in the Interim ECMWF Re‐Analysis (ERA‐Interim). An ensemble sensitivity analysis is used to provide information on the spatial and temporal forcing from mean sea‐level pressure and surface wind associated with extreme ocean wave height responses. Extreme ocean waves in the central North Sea arise due to intense extratropical cyclone winds from either the cold conveyor belt (northerly‐wind events) or the warm conveyor belt (southerly‐wind events). The largest wave heights are associated with northerly‐wind events which tend to have stronger wind speeds and occur as the cold conveyor belt wraps rearward round the cyclone to the cold side of the warm front. The northerly‐wind events provide a larger fetch to the central North Sea to aid wave growth. Southerly‐wind events are associated with the warm conveyor belts of intense extratropical cyclones that develop in the left upper tropospheric jet exit region. Ensemble sensitivity analysis can provide early warning of extreme wave events by demonstrating a relationship between wave height and high pressure to the west of the British Isles for northerly‐wind events 48 h prior. Southerly‐wind extreme events demonstrate sensitivity to low pressure to the west of the British Isles 36 h prior.