bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of seizure clustering using ultralong-term subcutaneous EEG monitoring
Authors: Novitskaya Yulia , Hirsch Martin , Schulze-Bonhage Andreas 
Published: October 2024

AbstractEpileptic seizures usually occur unpredictably yet not necessarily at random times. Cyclical patterns of seizure recurrence have been broadly described. Long-term seizure documentation may reveal individual cyclical seizure patterns; however, seizure reporting by patients or their caregivers is often inaccurate. Modern technologies for at-home monitoring of epileptic seizures enable continuous EEG recording for objective seizure counts over long-term timescales. Here, we present the clinical case of a patient with temporal lobe epilepsy due to hippocampal sclerosis who underwent ultralong-term subcutaneous EEG recording over a 1-year period, which revealed the occurrence of seizure clusters at three- to four-weekly intervals. The case demonstrates the possibility of detection of subject-specific seizure timing using a minimally invasive subcutaneous EEG recorder for ultralong-term at-home seizure monitoring. Information about individual seizure timing may contribute to a more personalized chronotherapeutic treatment approach in which antiseizure medication can be maintained at low doses during the low-risk periods and increased briefly before the anticipated seizures.
The DTALE Model: Designing Digital and Physical Spaces for Integrated Learning Environments
Authors: Tondeur Jo , Howard Sarah , Carvalho Ana Amélia , Kral Marijke , Petko Dominik , Ganesh Lakshmi T. , Røkenes Fredrik Mørk , Starkey Louise , Bower Matt , Redmond Petrea , Andresen Bent B. 
Published: October 2024

AbstractDespite the widely recognised impact of both digital and physical spaces as active contributors to teaching and learning processes, relatively little is known about the learning environment. Furthermore, it is time to explore the interplay between these two spaces. Therefore, we proposed employing a holistic approach to develop a new conceptual model for Designing Teaching and Learning Environments (DTALE). To do this, the paper presents first a critical review of the research literature underpinning learning environments, with a particular interest in the integration of the physical and digital spaces, to develop the DTALE model. In the second step, the DTALE model has been developed and validated by applying the model to existing cases from different contexts. Based on the study’s findings, we outline the implications for theory and practice. Limitations and suggestions for future research are also included.
Simple exact quantum search
Authors: Guţoiu Raj Alexandru , Tănăsescu Andrei , Popescu Pantelimon George 
Published: October 2024

AbstractWhile Grover’s search algorithm is asymptotically optimal, it does not always result in a real solution. If the search fails, the algorithm must be ran again from the beginning, conditionally doubling the effective number of oracle calls. Previous research attempted to fix this issue by modifying the oracle or alternating between numerically optimized reflectors. In this paper, we present an optimal initial state and reflector that produce an exact search with Grover’s algorithm at the cost of at most one additional oracle call beyond the optimum, a cost which can be nullified if we know a non-solution. We do this without modifying the oracle, without changing the diffuser at each step and even without any numerical optimization procedure required.
Formation of Multiscale Porous Surfaces via Evaporation-Induced Aggregation of Imprinted Nanowires with Highly Viscous Photocurable Materials
Authors: Kim Myung Seo , Shin Seungwoo , Kim Woo Young , Lee Sang Hoon , Park Seo Rim , Kim Seok , Cho Young Tae 
Published: October 2024

AbstractNumerous structures at the nano and microscale manifest distinctive properties with far-reaching implications across diverse fields, including electronics, electricity, medicine, and surface engineering. Established methods such as nanoimprint lithography, photolithography, and self-assembly play crucial roles in the fabrication of nano- and microstructures; however, they exhibit limitations in generating high-aspect-ratio structures when utilizing high-viscosity photocurable resins. In response to this inherent challenge, we propose a highly cost-effective approach facilitating the direct replication of high-aspect-ratio structures, specifically nanowires, through the utilization of anodized aluminum substrates. This study elucidates the streamlined fabrication process for multiscale porous surfaces achieved through the evaporation-induced integration of solid nanowires printed with high-viscosity photocurable resin.
Volumetric printing and non-destructive drug quantification of water-soluble supramolecular hydrogels
Authors: Ong Jun Jie , Jørgensen Anna Kirstine , Zhu Zilan , Telford Richard , Davies Philip J. , Gaisford Simon , Goyanes Alvaro , Basit Abdul W. 
Published: October 2024

AbstractVat photopolymerisation 3D printing is being actively explored for manufacturing personalised medicines due to its high dimensional accuracy and lack of heat application. However, several challenges have hindered its clinical translation, including the inadequate printing speeds, the lack of resins that give soluble matrices, and the need for non-destructive quality control measures. In this study, for the first time, a rapid approach to producing water-soluble vat photopolymerised matrices and a means of non-destructively verifying their drug content were investigated. Volumetric printing, a novel form of vat photopolymerisation, was used to fabricate personalised warfarin-loaded 3D-printed tablets (printlets). Eight different formulations containing varying amounts of warfarin (0.5–6.0% w/w) were used to print two different sized torus-shaped printlets within 6.5 to 11.1 s. Nuclear magnetic resonance (NMR) spectroscopy revealed the presence of only trace amounts of unreacted acrylate monomers, suggesting that the photopolymerisation reaction had occurred to near completion. All printlets completely solubilised and released their entire drug load within 2.5 to 7 h. NIR spectroscopy (NIRS) was used to non-destructively verify the dose of warfarin loaded into the vat photopolymerised printlets. The partial least square regression model built showed strong linearity (R2 = 0.980), and high accuracy in predicting the drug loading of the test sample (RMSEP = 0.205%). Therefore, this study advances pharmaceutical vat photopolymerisation by demonstrating the feasibility of producing water-soluble printlets via volumetric printing and quantifying the drug load of vat photopolymerised printlets with NIRS.
Graphical abstract
Integration of Electrical Properties and Polarization Loss Modulation on Atomic Fe–N-RGO for Boosting Electromagnetic Wave Absorption
Authors: Zhang Kaili , Yan Yuefeng , Wang Zhen , Ma Guansheng , Jia Dechang , Huang Xiaoxiao , Zhou Yu 
Published: October 2024

AbstractDeveloping effective strategies to regulate graphene's conduction loss and polarization has become a key to expanding its application in the electromagnetic wave absorption (EMWA) field. Based on the unique energy band structure of graphene, regulating its bandgap and electrical properties by introducing heteroatoms is considered a feasible solution. Herein, metal-nitrogen doping reduced graphene oxide (M–N-RGO) was prepared by embedding a series of single metal atoms M–N4 sites (M = Mn, Fe, Co, Ni, Cu, Zn, Nb, Cd, and Sn) in RGO using an N-coordination atom-assisted strategy. These composites had adjustable conductivity and polarization to optimize dielectric loss and impedance matching for efficient EMWA performance. The results showed that the minimum reflection loss (RLmin) of Fe–N-RGO reaches − 74.05 dB (2.0 mm) and the maximum effective absorption bandwidth (EABmax) is 7.05 GHz (1.89 mm) even with a low filler loading of only 1 wt%. Combined with X-ray absorption spectra (XAFS), atomic force microscopy, and density functional theory calculation analysis, the Fe–N4 can be used as the polarization center to increase dipole polarization, interface polarization and defect-induced polarization due to d-p orbital hybridization and structural distortion. Moreover, electron migration within the Fe further leads to conduction loss, thereby synergistically promoting energy attenuation. This study demonstrates the effectiveness of metal-nitrogen doping in regulating the graphene′s dielectric properties, which provides an important basis for further investigation of the loss mechanism.
Exploring soil pedogenesis through frequency-dependent magnetic susceptibility in varied lithological environments
Authors: Ouallali Abdessalam , Bouhsane Naima , Bouhlassa Saidati , Spalevic Velibor , Kader Shuraik , Michael Ruby , Sestras Paul 
Published: October 2024

AbstractThe use of percent frequency-dependent magnetic susceptibility (χfd%) is well-established for detecting superparamagnetic (SP) components in fine-grained soils and sediments. This study employs χfd% as a direct indicator of pedogenetic processes in soils from the Moroccan Rif region. Three soil transects (T1, T2, and T3), each comprising four soil cores with depths reaching 100 to 120 cm, were sampled from distinct lithological formations within an area subject to moderate to intense erosion. A total of 272 soil samples were collected and analyzed using MS2 Bartington Instruments, providing values to calculate χfd% and identify ultrafine ferrimagnetic minerals (SP, < 0.03 μm). In Quaternary fluvial terraces (T1) soils, approximately 60% of the samples indicate a mixture of SP, multidomain (MD), and Single Stable Domain (SSD) magnetic grains, while 30% contained coarser MD grains. Only 10% of the samples exhibit predominantly superparamagnetic (SP) grains. Soils on marly substrates (T2) showed 90% of samples with a combination of SP, MD, and SSD, and just 10% had SP grains. In contrast, soils from Villafranchian sandy deposits displayed χfd% values exceeding 10% in over 50% of samples, indicating that almost all iron components consist of SP grains. Physico-chemical analyses of the soils in profiles T1, T2, and T3 reveal distinct characteristics, including variations in clay content, organic matter, nutrient levels, and proportions of free and total iron. These results are important for understanding soil evolution and pedogenesis, with profiles T1 and T3 showing advanced development marked by high mineral iron, clay, and organic matter content. In contrast, profile T2 reflects a weak stage, influencing nutrient availability and contributing to overall soil dynamics in the respective profiles. The results of this study suggest that magnetic susceptibilities in these samples primarily originate from pedogenetic sources, revealing significantly advanced pedogenesis compared to T1 and T2 soils. The findings of this study align with previous research on soil erosion and degradation in the region, demonstrating that soils developed on terraces and marly substrates are more degraded and less stable than those on sandy substrates. This study underscores the utility of magnetic susceptibility as a rapid and effective indicator for initial soil assessment and gauging the degree of pedogenesis.
Konzepte für eine »Neue Generation«: Liebe und Liebesleben im Werk Helene Stöckers
Authors: Schuster Britt-Marie 
Published: October 2024

ZusammenfassungHelene Stöcker war eine der bekanntesten Frauenrechtlerinnen des ersten Drittels des 20. Jahrhunderts. Sie begriff sich als Vertreterin einer »Neuen Generation«, die eine neue sexuelle Moral etablieren, Geschlechterverhältnisse umgestalten und modernisieren wollte. Im Beitrag wird ihr Liebesideal thematisiert und gezeigt, welche Konzepte von Liebe und Liebesleben sie entwickelt. Die entsprechenden Ausdrücke werden als Schlüsselwörter ihres gesamten Werks gewertet. Es lässt sich erkennen, dass Stöcker versucht, traditionelle, insbesondere ethische und moralische Begriffe neu zu definieren, umzudeuten und neue diskurssemantische Netze zu etablieren, die das zukünftige Sprechen und Schreiben über Geschlechteridentität, heterosexuelle Beziehungen sowie über Sexualität beeinflussen sollen. Der Beitrag verknüpft die diachrone Genderlinguistik mit Kultur‑, Sozio- und Diskurslinguistik und berücksichtigt die Tatsache, dass mit der Neudefinition von Liebe neue Identitäts- und Beziehungskonzepte verbunden werden, die ihrerseits eine Alternative zu den in tradierten Diskursen vermittelten Geschlechterordnungen darstellen und für das soziale Netzwerk von Sexual- und Lebensreformer*innen prägend sind. Mit dem lebensreformerischen Konzept von Liebe ist der Wunsch nach einer kulturellen Erneuerung verbunden, die über die Lebensgestaltung von Individuen herausreicht und Vorstellungen von der »Veredelung der Rasse« beinhaltet. Es wird dafür argumentiert, dass trotz der Verwendung solcher Bezeichnungen wie Auslese oder Höherzüchtung sich ihre Zugangsweise zu bevölkerungspolitischen Themen nicht völkisch-nationalistisch verstehen lässt.
Metal–organic frameworks as highly effective platforms for enzyme immobilization–current developments and future perspectives
Authors: Rogacka Justyna , Labus Karolina 
Published: October 2024

AbstractThis study presents a thorough overview of metal–organic frameworks’ (MOFs) utility as supports for enzyme immobilization. It details a bibliometric analysis of the field from 2014–2023, based on 911 Web of Science articles. Research outlines the functional properties of MOFs, the enzyme groups, and common immobilization techniques. It showcases diverse enzyme-MOF combinations for numerous applications, including industrial biocatalysis, medical diagnostics, drug development, biomass conversion, environmental protection, and biosensor creation. Current development trends and future directions are identified through literature analysis. Latent Dirichlet Allocation (LDA) modeling revealed key research themes over the years, highlighting shifts in focus towards advanced catalytic methods and adsorption techniques. Additionally, a word cloud generated for 2024 publications indicates an increasing emphasis on specialized applications involving ZIFs, nanoparticles, and magnetic structures. Key future perspectives include new MOF materials, such as biologically derived MOFs, core–shell magnetic hierarchical porous MOFs, nanoMOFs, and mesoporous MOFs. Novel materials inspired by MOF carriers, such as covalent organic frameworks (COFs) and metal–organic aerogels (MOAs), are also highlighted. Lastly, the study emphasizes the potential for multienzymatic systems and multifunctional MOF-enzyme composites, facilitating multiple functionalities within a single system.
The interconnectedness between Ubuntu principles and generative artificial intelligence in distance higher education institutions
Authors: Suliman Zuleika , Mohale Ntshimane Elphas , Maphoto Kgabo Bridget , Sevnarayan Kershnee 
Published: October 2024

AbstractThe interconnectedness of African philosophical principles of Ubuntu with generative artificial intelligence may provide an inclusive approach to distance higher education. This fusion may improve and provide customised learning, access quality education, collaboration, inclusivity, strengthens lecturer support and development, and a culturally relevant experience that acknowledges the communal interests of all stakeholders. Generative artificial intelligence promotes epistemological access for all students irrespective of their diverse social, financial, and linguistic backgrounds and redefines higher education experiences and practices while the principles of Ubuntu prioritise the well-being of stakeholders. The objective of this conceptual article was to explore the interconnectedness between Ubuntu principles and generative artificial intelligence perspectives in distance higher education institutions to reimagine methods of teaching and learning. This article is grounded in the theory of the Ubuntu principles and advocates for a paradigm shift in higher education practices. It contends that integrating African philosophical principles into the implementation of generative artificial intelligence’s learning provides a more inclusive and culturally relevant approach to education. The notable highlights confirm that Ubuntu principles dismantle oppressive systems, restore self-determination for all students and promote change and reconciliation through the use of generative artificial intelligence. This approach can be applied to distance higher education institutions to create inclusive learning experiences that gives precedence to a sense of belonging, mutual support, and ethical considerations.
Catching on: Work stress, employee wellbeing, and the moderating role of team-level emotional contagion
Authors: Hernandez Grande Aglae , Farr-Wharton Ben , Sharafizad Fleur , Darcy Simon , Gavin Mihajla 
Published: October 2024

Abstract
Work stress and employee wellbeing have gained heightened attention since the COVID-19 pandemic. Until now, organizations have primarily sought to conceptualize these variables as an individual-level phenomenon; thereby neglecting the potential influence of social dynamics within the workplace. Drawing on conservation of resources and emotional contagion theories, this study examines the extent to which team-level emotional contagion moderates the impact of stress on wellbeing, factoring in multilevel effects. Data from 237 professional services employees nested within 41 teams was analyzed. The results show support for emotional contagion as a team-level moderator between individual-level work stress and employee wellbeing. The role of organizational resources in shaping stress and wellbeing outcomes was also significant. This study underscores the significance of team dynamics and organizational resources in shaping employee wellbeing. Well-targeted, stress alleviation, and team-contagion enhancing initiatives will have a more positive impact on wellbeing, than individually targeted stress alleviation initiatives in isolation.
Srebrenica as a Marker of Memory in Bilateral Relations Between Serbia and Bosnia and Herzegovina in the Light of Ontological Security
Authors: Jagiełło-Szostak Anna 
Published: October 2024

AbstractThis article aims to analyze the impact of memory on security/foreign policy using the example of Serbia and Bosnia and Herzegovina’s bilateral relations. The basis for these considerations is the concept of ontological security. It indicates the construction of the identity of the state and is implemented through political decisions and social practices (for example remembering important historical events). Here, memory is treated as a social construct. In addition, the article focuses on memory leading to the formation of state identity, also seen in the international sphere. Historical memory has a considerable impact on bilateral relations between countries that used to be in conflict, like Serbia and BiH. In the example analyzed, leaders use historical memory to create separate identities, commemorate chosen and appropriate victims/heroes or important dates, historical sites, monuments events and develop selective narratives. The most significant elements in the analysis of the historical memory of Serbia and BiH relations are (1) the goals of foreign and security policy of Serbia and BiH (2) the contemporary narrative of the Srebrenica genocide and its perception by governments of Serbia, BiH, and by Bosnian Serbs and Bosniaks, and (3) an official Srebrenica commemoration (memorials, Srebrenica Memorial Day).
Teleofunction in the Service of Computational Individuation
Authors: Fresco Nir , Artiga Marc , Wolf Marty J. 
Published: October 2024

AbstractOne type of computational indeterminacy arises from partitioning a system’s physical state space into state types that correspond to the abstract state types underlying the computation concerned. The mechanistic individuative strategy posits that computation can be uniquely identified through either narrow physical properties exclusively or wide, proximal properties. The semantic strategy posits that computation should be uniquely identified through semantic properties. We develop, and defend, an alternative functional individuative strategy that appeals—when needed—to wide, distal functions. We claim that there is no actual computation outside of a functional context. Desiderata for the underlying notion of teleofunction are discussed.
Value, knowledge and reputation: zoological exchange by Australian museums, 1870–1900
Authors: Reese Henry , Finney Vanessa , Ville Simon 
Published: October 2024

Abstract
The burgeoning nineteenth-century public-museum sector built a significant part of its natural-history specimen collections through extensive international trading. The early 2020s has seen an upsurge of scholarly interest in this largely overlooked trade. Exchange was a distinctive aspect of the natural-history trade that reveals much about the diverse practices and motives of the institutional collectors. Economic-geographic benefits included conserving the limited financial resources of museums and exploiting complementarities in the geographic distribution of specimens. Collection management, institutional reputation, social connection and international diplomacy were also part of a complex mix of value making that shaped this important international trade. We analyse the exchange practices of the three largest museums in the Australian colonies in the final three decades of the nineteenth century who exchanged Australia's ‘rare and curious’ fauna with collectors across the globe. By deploying and analysing extensive, comparative data on a particular form of natural history, zoology, and a particular kind of trade, exchange trading, among three Australian museums, this paper extends and enriches recent scholarship on the mobility of natural-history specimens and how they were traded.
Novel miRNA biomarkers for alveolar echinococcosis: sequencing and clinical validation
Authors: Ma Jideng , Li Zian , Liu Lanmin , Luo Xiaoqin , Ma Xiaoya , Zhang Yumei , Jiang Lei , A Xiangren 
Published: October 2024

Abstract
This study aimed to explore extracellular microRNA derived from Echinococcus multilocularis (EM) in the plasma of patients with alveolar echinococcosis (AE) and assess its potential as a diagnostic biomarker. EM-derived miRNAs were identified in plasma samples from 20 AE patients through miRNA sequencing. Three novel miRNA molecules (emu-miR-novel 1, 2 and 3) were predicted through bioinformatic analysis to elucidate their chromosomal locations, secondary structures and precursor forms. Subsequently, plasma samples from 30 AE patients and 30 controls were utilized to establish an assay via stem-loop reverse transcription PCR, optimizing primers, reaction systems, and conditions to assess cross-reactivity and sensitivity. Clinical validation revealed that emu-miR-novel 1 had the highest diagnostic accuracy, with an area under the curve (AUC) of 0.8994, a P value of less than 0.0001, a sensitivity of 83.3%, and a specificity of 86.7%. Statistically significant differences were observed between the groups for emu-miR-novel 1 (P < 0.05), whereas emu-miR-novel 2 and 3 showed AUC values of 0.7922 and 0.6883, with P values of 0.0001 and 0.012, respectively, indicating no significant difference between groups (P > 0.05). Furthermore, the assay showed no cross-reactivity with samples from 18 common viruses, 4 parasitic infections, and miRNAs from AE sequenced from 8 species, confirming its high specificity. Emu-miR-novel 1 exhibited a sensitivity of 1 femtomolar. Emu-miR-novel 1 holds promise as a key diagnostic tool for AE, offering a novel perspective and approach for disease diagnosis.