bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of quality of life of patients operated for chronic pancreatitis
Authors: Tarasenko S V , Natal’skiy A A , Zaytsev O V , Sokolova S N , Bogomolov A Yu , Rakhmaev T S , Bakonina I V , Kadykova O A 
Published: October 2017

Aim. Comparative analysis of the long-term results of surgical treatment of patients with chronic pancreatitis.
Methods. The study included patients with complicated clinical forms of chronic pancreatitis including: ductal pancreatic hypertension, main pancreatic duct concrements, marked fibrous restructuring of the pancreatic parenchyma and presence of calcifications, presence of biliary hypertension, portal hypertension syndrome, duodenostasis syndrome, chronic abdominal pain syndrome, retention and post-necrotic cysts. Patients were divided into 3 groups: group 1 included patients with chronic pancreatitis receiving conservative treatment (n=32), group 2 - patients who underwent the Frey pancreatic resection (n=24) and group 3 - Beger pancreatic resection (n=9). The assessment was performed according to the most spread specific questionnaire in gastroenterology GSRS (Gastrointestinal Symptom Rating Scale).
Results. The quality of life of patients who underwent both Frey and Beger pancreatic resection was significantly higher than the quality of life of patients in whom chronic pancreatitis was treated conservatively. Quality of life of patients who underwent Frey or Beger pancreatic resection did not differ significantly. Malabsorption syndrome has a significant effect on the quality of life of patients who underwent surgical treatment of chronic pancreatitis. The GSRS questionnaire demonstrated low sensitivity in detecting malabsorption syndrome.
Conclusion. Quality of life of patients who underwent surgical treatment of chronic pancreatitis is statistically significantly higher than in patients receiving conservative treatment; correction of existing quality of life questionnaires is required in order to identify malabsorption syndrome.
Oral diseases prevalence among mariners of the Black sea fleet of the Russian Federation
Authors: Nikitenko V V , Grebnev G A , Kovalevskiy A M , Iordanishvili A K , Chernysh V F , Murynin V A , Teplov E V , Vasil’eva L V , Kovalevskiy V A , Vasil’eva M I 
Published: October 2017

Aim. Investigation of the prevalence and severity of dental diseases of seafarers of the Black Sea Russian Fleet, as well as the need for various types of dental care.
Methods. Thorough dental examination of 785 mariners aged 18 to 40 years was performed. Group 1 consisted of 510 conscripts aged 18-27 years, group 2 - 275 military contract personnel aged 18-40 years. A thorough dental examination was performed using mouth mirror and probe, as well as the graduated periodontal probe. Dental caries extension and DMF (decayed-missing-filled) index were determined. Evaluation of periodontium was carried out according to the CPITN index (Community Periodontal Index of Treatment Needs), hygiene indices (Fedorov, Y.A., Volodkina V.V., 1971) and Sulcus Bleeding Index (SBI, Мuhlemann, Son, 1971).
Results. Investigation of oral disease prevalence among seafarers of the Black Sea Russian Fleet showed its increase during the last twenty years. Particularly, dental caries prevalence among conscripts and military contract personnel of Black Sea Fleet reached 97.64±0.36% and 99.63±0.36%, respectively (DMF 8.85±1.25 and 13.30±2.05, respectively), and prevalence of chronic generalized periodontitis was 10.70±1.37% and 18.30±2.33%, respectively (p
Experimental validation of gene therapy for ischemic stroke
Authors: Sokolov M E , Bashirov F V , Safiullov Z Z 
Published: October 2017

Aim. To develop a protocol of direct and cell-mediated gene therapy for ischemic stroke.
Methods. Viral vector carrying green fluorescent protein (GFP) reporter gene was created on the basis of human adenovirus serotype 5 (Ad5). The umbilical blood supply was preserved according to instructions of Kazan State Medical Uuniversity Stem cell bank. Umbilical cord blood mononuclear cells were isolated in a ficoll density gradient by standard procedure and transduced with Ad5-GFP. Ischemic cerebral stroke in rats was caused by distal occlusion of the middle cerebral artery through trephination hole in a temporal bone under surgical microscope. Within four hours after modeling stroke in the anesthetized animals laminectomy was performed at the L4-L5 level, and (1) 0.9% sodium chloride solution, (2) Ad5-GFP and (3) umbilical cord blood mononuclear cells + Ad5-GFP were inserted intrathecally. Survival, targeted migration to the focus of neurodegeneration, the ability to synthesize recombinant protein and the effect of umbilical cord blood mononuclear cells on the infarction area were assessed using luminescent microscopy and morphometric analysis.
Results. GFP expression in the area of the stroke was established 3 weeks after stroke modeling, both after intrathecal insertion of Ad5-GFP and after xenotransplantation of umbilical cord blood mononuclear cells Ad5-GFP transduced ex vivo. When comparing the areas of cerebral infarction 3 weeks after modeling the stroke, in animals from umbilical cord blood mononuclear cells + Ad5-GFP group the median of the infarction area was 47.4% less than in animals receiving isotonic saline solution.
Conclusion. Umbilical cord blood mononuclear cells + Ad5-GFP after intrathecal insertion to animals with ischemic stroke, are capable of targeted migration to the neurodegeneration site as well as of recombinant protein synthesis; the results suggest the expediency of delivering therapeutic genes to ischemic zone via umbilical cord blood mononuclear cells overexpressing neurotrophic factors.
Change in affordability of medications in Kazan in 2011 and 2015 as a reflection of state initiatives to regulate drug prices
Authors: Razzakova Ch M , Ziganshina L E 
Published: October 2017

Aim. Performing comparative analysis of drug prices in 2011 and 2015 in Kazan to assess the effectiveness of state initiatives to ensure the affordability of medicines.
Methods. The collection and processing of data was performed according to methodology developed by Health Action International and World Health Organization (WHO/HAI). We studied the availability and prices of 30 medicines in public and private pharmacies in Kazan in 2011 and 2015 and analyzed the procurement prices of the same medicines in inpatient hospitals. Recording and analysis were performed using standardized MS Excel WHO/HAI Workbook. Medicine prices were compared with international reference prices and were expressed as median price ratio.
Results. The analysis showed a decrease in medicine prices in 2015 compared to 2011. In public and private sectors median price ratio of the originator brands reduced by about 3 times, and of the lowest price generics reduced by 1.5 times. A decrease in procurement prices by more than 2 times for generics and more than 6 times for the original brands was also revealed in 2015 in comparison with 2011.
Conclusion. State initiatives to regulate drug prices contributed to the price reduction by 1.5-3 times in 2015 compared to 2011; changes in the procedures for the medicines procurement at the legislative level resulted in reduction of procurement prices by more than 2 times for generic drugs in 2015 compared to 2011.
Occupational allergic diseases in the Samara region: features and problems
Authors: Nikiforova G A , Spiridonov A M , Gavryushin M Yu 
Published: October 2017

Aim. Improving the system of identifying occupational allergic diseases based on the anaysis of the features of occupational allergic morbidity in the Samara region for the period from 2005 to 2014.
Methods. Comprehensive retrospective study of occupational allergic morbidity in the Samara region was carried out on the data from 3229 occupational diseases (poisoning) registry cards including 278 occupational allergic diseases registry cards, as well as 262 acts on cases of occupational diseases. Obtained data were compared to the official data of the Federal budgetary healthcare institution «Federal center of hygiene and epidemiology» of Rospotrebnadzor and the reports of the Office of Rospotrebnadzor in the Samara region «On the sanitary-epidemiological welfare of population» for the relevant years.
Results. The proportion of occupational allergic diseases in the Samara region is in average 7.68±1.03% of all newly diagnosed cases of occupational diseases varying from 12.25% in 2005 to 3.22% in 2013, exceeding the same indicator across Russia. In the structure of occupational allergic diseases the most common nosological forms were revealed: bronchial asthma - 37.86%, allergic rhinitis - 25.07%, allergic (atopic) dermatitis - 7.93%, eczema - 7.68%. In 78.38% of cases the priority allergens in the region were chemical allergens: formaldehyde, chromium, nickel, molybdenum and other metals compounds, antibiotics, disinfectants, chlorine and synthetic detergents and others. 38.07% of cases of occupational allergic diseases were found to be registered in Samara, 26.15% of cases - in Tolyatti, and 5.50% of cases - in Otradnoye in the Samara region. The proportion of occupational allergic diseases found at periodic medical examinations was in average 29.31±4.5%.
Conclusion. The identified features of occupational allergic morbidity in the Samara region show the necessity to improve the organization and conduct of preventive measures, periodic medical examinations as well as further development of the regulatory framework.
Gender aspects of work motivation among oncologists
Authors: Gataullin I G , Zabirova L M , Gataullin I I 
Published: October 2017

Aim. Study of work motivation and job satisfaction factors among oncologists from a gender perspective.
Methods. The survey involved 102 physicians-oncologists of the Republic of Tatarstan - 47% men and 53% women. The study included the following methods: observation, questionnaire, interview.
Results. Among all corporate factors, the work content (the functions performed, complexity, diversity, responsibility) was highly evaluated by men - 8.26 points (on a 10-point scale), the style and methods of leadership in the unit - 7.24 points. The highest score (above 8 points) among female doctors was given to organizational culture, training, labor peer review by colleagues, the style and methods of leadership in the unit, as well as standards, rules, regulations, and their implementation. Job satisfaction indicators among male doctors were generally lower than among women in all 16 occupational characteristics. Among the leading motivators oncologists place work content, positive attitude towards their profession, mission and goals of the clinic. They oppose demotivators such as pay rate, moral motivation, career opportunities and provide an acceptable level of work motivation for doctors. Compensation in the form of an award came out on top among the forms of stimulation both in men and in women. Forms of non-cash stimulation are also quite popular with doctors and are approximately equal in men and women: advanced training in the leading domestic and foreign clinics, payment of sports occupations, days off. Women prefer additional vacation, a praise, acknowledgement from the executive management of the clinic. Men appreciate more position increase, awarding of honorary title and especially provision of larger freedom and powers at work.
Conclusion. Gender studies of motivation demonstrated the differences in the attitude towards work, in its most important characteristics, labor values among male and female oncologists.
ANÁLISE COMPARATIVA DA FORÇA MUSCULAR RESPIRATÓRIA DE PRIMIGESTAS NO PUERPÉRIO IMEDIATO DE PARTO NORMAL E DE NULIGESTAS
Authors: Wagner Caroline Schwingel , Assmann Gabriella , Gass Ricardo , Hopp Marciele Silveira , Cardoso Grazielly Gass , Cardoso Dannuey Machado , Paiva Dulciane Nunes 
Published: October 2017

Este artigo visa analisar a força muscular respiratória (FMR) de puérperas primíparas de parto normal e nulíparas. Trata-se de estudo do tipo caso-controle que avaliou 59 mulheres alocadas no grupo puérperas (GP) (primigestas, n=29) e no grupo controle (GC) (nuligestas, n=30). Foram avaliadas características antropométricas e FMR (PImax e PEmax) por meio da manovacuometria digital. O teste t Student comparou dados antropométricos e da FMR entre os grupos. A correlação de Pearson (p
Crescimento e composição do óleo essencial de malvariço cultivado sob salinidade e doses de biofertilizante
Authors: Da Silva Mesquita Sergiane Beatriz , Da Costa Rafael Santiago , Amorim Aiala Vieira , De Lacerda Claudivan Feitosa , Da Fonseca Aluísio Marques 
Published: October 2017

Os efeitos que a salinidade do solo e da água provocam nas culturas podem ser superados utilizandose biofertilizantes. Assim, objetivou-se com o presente estudo avaliar o efeito da salinidade e do biofertilizante bovino no crescimento, na produção de óleos essenciais e nos teores de carboidratos e cloreto de plantas
de malvariço (Plectranthus amboinicus). O experimento foi conduzido em casa de vegetação no período de março a maio de 2013, em vasos plásticos com capacidade de 7,5 L. O delineamento experimental utilizado foi inteiramente casualizado, em um arranjo fatorial 2 x 4, sendo dois níveis de salinidade da água de irrigação
(S1=0,7 e S2=3,1 dS m-1) e quatro níveis de biofertilizante bovino líquido aplicados ao solo, correspondendo a B1=0, B2=10, B3=20 e B4=30% do volume do solo, com cinco repetições. Foram avaliadas: massa seca da raiz, do caule e das folhas, teores foliares de carboidrato, de cloreto e de óleos essenciais. A salinidade
reduziu a biomassa seca das raízes. Porém, a aplicação de biofertilizante e a interação entre os fatores não influenciaram as variáveis biométricas, os teores de carboidratos e os de cloreto. Em todas as condições avaliadas, o óleo essencial de Plectranthus amboinicus apresentou ésteres, álcoois, fenóis, cetonas e
terpenóides.
Níveis de dano e de controle do percevejo-verde-da-soja Nezara viridula (Hemiptera: Pentatomidae) em feijão-caupi
Authors: Silva Paulo Henrique , Sobrinho Candido Athaide 
Published: October 2017

Estudos sobre níveis de danos causados por insetos são importantes para tomada de decisão de controle de pragas nas culturas e implementação de práticas de manejo integrado de pragas. Em culturas como as de soja e feijão-comum, esses níveis já foram estudados e definidos, e o manejo de suas pragas já
está estabelecido. Entretanto, no feijão-caupi, que possui muitas pragas semelhantes às da soja e do feijãocomum, parâmetros utilizados para tomada de decisão de controle ainda precisam ser estabelecidos. Assim, objetivou-se com este estudo determinar os níveis de danos e de controle do percevejo-verde-da-soja, Nezara
viridula em feijão-caupi. Gaiolas teladas foram colocadas em campo sobre estrados, e, em seu interior, cinco vasos contendo uma planta em cada um deles, o que equivaleu a uma população de cinco plantas por metro linear. Os níveis de densidades populacionais de percevejos nas gaiolas foram o equivalente aos de
0; 2; 4; 6 e 8 adultos m-1. A infestação pelos percevejos ocorreu por todo o período reprodutivo da cultura, compreendendo o início da emissão das vagens até a sua completa maturação fisiológica, que corresponde a aproximadamente 20 dias. Diariamente, as gaiolas eram observadas, e os insetos mortos substituídos; ao
final do período de infestação, avaliou-se a produção de grãos íntegros. O aumento de um percevejo por metro de fileira proporcionou perdas na produção de 6,36%. O nível de controle estimado para o percevejoverde-da-soja em feijão-caupi é de 0,7 percevejos por metro de fileira.
Do Social Grants Displace Remittances? Evidence From South Africa
Authors: Biyase Mduduzi , Zwane Talent , Rooderick September 
Published: October 2017

This paper employs a newly-available and representative National Income Dynamics Study (NIDS) data of South African households to investigate whether social grants crowd-out or displace remittances. The estimated results based on full sample reveal that while the social grants have a negative impact on the amount of remittances received, the effect is statistically insignificant – social grants do not crowd out or displace remittances. The coefficient on the social grant is also insignificant in both sub-samples (rural and urban), consistent with the results on the full sample
O conflito da diferença na escola: uma visão psicanalítica
Authors: Archangelo Ana , Oyama Daniela Kitawa , Pompeu Maria Lígia 
Published: October 2017

Vivemos em tempos de hegemonia do discurso sobre a inclusão, sobre o direito às diferenças, que, embora fundamental, tem gerado muito desconforto no interior das escolas. Este artigo procura demonstrar que o dilema entre a busca pela igualdade e a busca pela diferença não é falso para os moldes do discurso de uma agenda estritamente política; mas o é, de uma perspectiva social, desde que se leve em consideração que esta última não se dissocia de uma perspectiva psíquica. À luz do referencial psicanalítico kleiniano e bioniano, a diferença é concebida como o ponto de inflexão que inaugura o conflito e com ele coincide. A partir disso, o artigo discute que as instituições escolares revelam diferentes maneiras de acolher (ou não) o que cada um traz para a escola – suas particularidades, ansiedades, formas de sentir, de aprender, de desenvolver as diferenças –, acabando por oferecer, às reais necessidades dos sujeitos que ali estão, diariamente, distintas possibilidades de elaboração. São características de alguns perfis de instituição, os quais se descrevem como: a escola negligente; a escola homogeneizadora; a escola ingênua e a escola acolhedora.
Formação, função e formas de provimento do cargo do gestor escolar: as diretrizes da política educacional e o desenvolvimento teórico da administração escolar
Authors: Abdian Graziela Zambão , Fernanda Hojas Viviani , Oliveira Maria Eliza Nogueira 
Published: October 2017

O objetivo deste trabalho é, mediante o tensionamento entre as diretrizes da política educacional e o movimento teórico da área, analisar questões históricas e atuais referentes à formação, à função e às formas de provimento do cargo do gestor escolar, entre os anos 1970 e 2000. Para isso, utilizamos entrevistas semiestruturadas realizadas em escolas públicas municipais e estaduais, assim como em uma universidade pública do interior do estado de São Paulo, com integrantes do curso de Pedagogia. Da análise realizada, finalizamos com alguns apontamentos; entre eles, a possibilidade de reacender a discussão, iniciada nos idos dos anos 1960, sobre a necessidade de formação inicial sólida do gestor escolar, para que ele possa exercer a competência pedagógica adquirida e o compromisso político conquistado ao longo desses anos; e interagir de forma crítica e consciente com as diretrizes da política educacional.
PENGEMBANGAN STANDAR PELAKSANAAN PRAKTIK KERJA INDUSTRI (PRAKERIN) SISWA SMK PROGRAM KEAHLIAN TEKNIK PEMESINAN DI WILAYAH SURAKARTA
Authors: Edi Sarwo , Suharno Suharno , Widiastuti Indah 
Published: October 2017

<p>Tujuan penelitian ini adalah untuk 1) Mengetahui bagaimana pelaksanaan prakerin pada program keahlian Teknik Pemesinan di SMK wilayah Surakarta. 2) Mengembangkan Standar Pelaksanaan Prakerin pada program keahlian Teknik Pemesinan di SMK wilayah Surakarta.Penelitian ini merupakan penelitian komparatif kualitatif. Populasi dalam penelitian ini adalah SMK dengan program keahlian Teknik Pemesinan di Surakarta. Sampel yang terpilih adalah SMK N 5 Surakarta, SMK Pancasila Surakarta, dan SMK PGRI 1 Surakarta dengan teknik pengambilan sampel purposive sampling. Penelitian ini dimulai dari pengumpulan data, analisis data dan pengambilan Kesimpulan. Jenis data yang dugunakan yaitu data kualitatif. Teknik Pengumpulan data menggunakan dokumentasi dan wawancara. Analisis data pada penelitian ini menggunakan analisis dokumen.Berdasarkan hasil penelitian, alur pelaksanaan prakerin yang dapat diusulkan adalah sebagai berikut 1) Tahap Sinkronisasi Industri, 2) Tahap Evaluasi Kelayakan Industri, 3) Tahap penetapan Industri Sementara, 4) Tahap Sosialisasi Prakerin, 5) Tahap Pemilihan DU/DI oleh Peserta Prakerin, 6) Tahap Final Penetapan Industri, 7) Tahap Pembuatan Kerjasama dengan DU/DI, 8) Tahap Pembekalan Prakerin, 9) Tahap Pelaksanaan Prakerin, 10) Tahap Pembimbingan Peserta Prakerin, 11) Tahap Penanganan Siswa Bermasalah, 12) Tahap Penarikan Prakerin, 13) Tahap Penilaian dan Sertifikasi Peserta Prakerin, dan 14) Tahap Pengumpulan dan Pemberkasan Rekaman Prakerin.<strong></strong></p><strong>Kata Kunci</strong>: Sekolah Menengah Kejuruan, Prakerin, SOP
PENGEMBANGAN SISTEM INFORMASI AKADEMIK BERBASIS WEB SEBAGAI SISTEM PENGOLAHAN NILAI SISWA DI SMK NEGERI 1 KUDUS
Authors: Suryandani Farid , Basori Basori , Maryono Dwi 
Published: October 2017

<p>Penelitian ini bertujuan untuk menghasilkan sebuah sistem informasi pengelolaan nilai untuk memudahkan guru dalam mengelola nilai rapor siswa. Sistem informasi ini ditujukan untuk digunakan di Sekolah Menengah Kejuruan (SMK). Sistem informasi ini berbasis web, sehingga dapat diakses oleh guru untuk mengelola nilai dan siswa bisa melihat hasil belajarnya. Metode yang digunakan dalam penelitian ini adalah metode penelitian dan pengembangan (R&amp;D) yang dilaksanakan di SMK Negeri 1 Kudus. Teknik pengumpulan data yaitu melalui wawancara, kuesioner dan dokumentasi. Pengembangan Sistem Informasi Akademik Berbasis Web Sebagai Sistem Pengolahan Nilai Siswa di SMK Negeri 1 Kudus dilaksanakan dengan lima tahap yaitu : (1) <em>Communication</em> merupakan diskusi antara peneliti dengan pihak sekolah tentang pengembangan sistem. (2) <em>Planning</em> merupakan tahap perancangan kebutuhan fungsional, kebutuhan <em>software</em> dan kebutuhan <em>hardware</em> dari sistem yang dikembangkan. (3). <em>Modeling</em> yaitu tahap perancangan sistem yang berfokus pada pemrosesan data. Tahap ini dimulai dengan pembuatan <em>Usecase Diagram</em>, <em>Flowchart</em>, DFD (<em>Data Flow Diagram</em>), ERD (<em>Entity Relationship Diagram</em>), Desain Tabel Basis Data dan Relasinya dan pembuatan Desain Tampilan Sistem. (4) <em>Construction</em> yaitu tahapan pada rancangan yang telah dibuat, di implementasikan ke dalam kode (program). (5) <em>Deployment</em> merupakan tahap pengujian kepada pihak SMK untuk mendapatkan umpan balik tentang kelayakan dan pengembangan sistem yang selanjutnya. Nilai akhir dari penelitian ini adalah 93,1% dari ahli sistem, 85,3% dari guru dan staf tata usaha dan 82,4% dari siswa, sehingga dapat disimpulkan bahwa sistem ini sangat layak untuk digunakan.<strong></strong></p><strong>Kata Kunci :</strong> Sistem Informasi Akademik, berbasis web, pengelolaan nilai siswa
Budowa bariery jelitowej
Authors: Węgrzyn Dagmara , Adamek Karolina , Łoniewska Beata 
Published: October 2017

Bariera jelitowa jest zbudowana z kilku warstw. Tworzą ją mikroorganizmy jelitowe, ochronna warstwa śluzu, nabłonek jelitowy oraz komórki układu krwionośnego, chłonnego, immunologicznego i nerwowego. Warstwa śluzu, która zapobiega przyleganiu i wnikaniu patogenów w głąb ściany jelita, jest również siedliskiem mikroorganizmów jelitowych, które są jednym z kluczowych i najbardziej dynamicznych elementów bariery jelitowej. Mikrobiotę tworzą głównie bakterie beztlenowe, a także tlenowe, drożdże i wirusy. Eksosytem jelitowy podlega nieustannym zmianom w życiu człowieka, dąży jednak do zachowania równowagi, która jest gwarantem zdrowia. Elementem bariery fizycznej jest pojedyncza warstwa komórek nabłonkowych utworzona głównie przez enterocyty, które oprócz wchłaniania substancji odżywczych wpływają na rozwój aktywności immunologicznej, pośrednicząc w uwalnianiu cytokin oraz ekspresji receptorów uczestniczących w odpowiedzi immunologicznej. Na szczytowo-bocznej powierzchni błony komórkowej zlokalizowane są ścisłe złącza. To one są najistotniejszym elementem regulującym przepuszczalność jelitową. Do połączeń między komórkami nabłonka należą także złącza mechaniczne oraz połączenia szczelinowe. Pod warstwą komórek nabłonkowych znajduje się blaszka właściwa, która zawiera jelitową tkankę limfatyczną, jelitowy układ nerwowy oraz tkankę łączną. Bariera jelitowa podlega ciągłym, dynamicznym zmianom, których wypadkowa warunkuje stan zdrowia lub choroby.