bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns of red tree vole distribution and habitat suitability: implications for surveys and conservation planning
Authors: Rosenberg Daniel K. , Davis Raymond J. , Van Norman Kelli J. , Dunk Jeffrey R. , Forsman Eric D. , Huff Robert D. 
Published: December 2016

AbstractEnvironmental regulations often require wildlife surveys prior to habitat disturbance to avoid impacts or as the basis for planning mitigation, yet project‐level surveys may not provide the insights needed to guide long‐term management. Management of the red tree vole (Arborimus longicaudus) has largely been based on such surveys. As an alternative approach, we evaluated distribution patterns using frequency of red tree vole occurrence and habitat suitability models to guide conservation planning. We developed a suite of models based on subsets of covariates from two previously developed models and evaluated the extent to which spatial covariates improved the models. We used presence–absence data that were collected from 364 randomly selected 1‐ha Current Vegetation Survey and Forest Inventory and Analysis plots to develop models and describe occurrence patterns. The best models included a spatial covariate, maximum tree diameter, distance from suitable habitat, forest age class, and the interaction between maximum tree diameter and forest age class. We compared performance of the previously published models, our best model, and an ensemble model that used predictions from all three models. Under the ensemble model, correct classification rates were relatively high and considerably improved, suggesting that the application of all three models provided greater accuracy than any individual model. We argue that habitat models, coupled with spatial patterns of the frequency of occurrence, can provide useful tools for addressing species management and may provide more insight than project‐level surveys. The use of habitat suitability models can therefore be closely tied to red tree vole management decisions and conservation strategies, as well as reducing survey costs that otherwise often make projects infeasible.
Integrating multiple data sources in species distribution modeling: a framework for data fusion
Authors: Pacifici Krishna , Reich Brian J. , Miller David A. W. , Gardner Beth , Stauffer Glenn , Singh Susheela , McKerrow Alexa , Collazo Jaime A. 
Published: December 2016

AbstractThe last decade has seen a dramatic increase in the use of species distribution models (SDMs) to characterize patterns of species’ occurrence and abundance. Efforts to parameterize SDMs often create a tension between the quality and quantity of data available to fit models. Estimation methods that integrate both standardized and non‐standardized data types offer a potential solution to the tradeoff between data quality and quantity. Recently several authors have developed approaches for jointly modeling two sources of data (one of high quality and one of lesser quality). We extend their work by allowing for explicit spatial autocorrelation in occurrence and detection error using a Multivariate Conditional Autoregressive (MVCAR) model and develop three models that share information in a less direct manner resulting in more robust performance when the auxiliary data is of lesser quality. We describe these three new approaches (“Shared,” “Correlation,” “Covariates”) for combining data sources and show their use in a case study of the Brown‐headed Nuthatch in the Southeastern U.S. and through simulations. All three of the approaches which used the second data source improved out‐of‐sample predictions relative to a single data source (“Single”). When information in the second data source is of high quality, the Shared model performs the best, but the Correlation and Covariates model also perform well. When the information quality in the second data source is of lesser quality, the Correlation and Covariates model performed better suggesting they are robust alternatives when little is known about auxiliary data collected opportunistically or through citizen scientists. Methods that allow for both data types to be used will maximize the useful information available for estimating species distributions.
A Comparative Study of Functionalized High‐Purity Carbon Nanotubes towards the V(IV)/V(V) Redox Reaction Using Cyclic Voltammetry and Scanning Electrochemical Microscopy
Authors: Steimecke Matthias , Rümmler Stefan , Schuhmacher Nils‐Frederik , Lindenberg Titus , Hartmann Mark , Bron Michael 
Published: December 2016

AbstractFunctionalized high purity carbon nanotubes (CNTs) with various amounts of oxygen containing surface groups were investigated towards the relevant redox reactions of the all‐vanadium redox flow battery. The quinone/hydroquinone redox peaks between 0.0 and 0.7 V vs. Ag|AgCl|KClsat. were used to quantifying the degree of functionalization and correlated to XPS results. Cyclic voltammetry in vanadyl sulfate‐containing 3 M H2SO4 as a common supporting electrolyte showed no influence of the amount of surface groups on the V(IV)/V(V) redox system. In contrast, the reactions occurring at the negative electrode (V(II)/V(III) and V(III)/V(IV)) are strongly affected by oxygen surface groups. However, under modified experimental conditions, SECM experiments detecting the consumption of VO2+ molecules by CNT thin films in pH=2 solution show improved onset potentials with increased surface oxygen content up to ∼ 3 at%. Further increase in surface oxygen up to 8 at% led to minor improvement. These dissimilar results under different experimental conditions are rationalized by suggesting that oxygen functional groups do not form the active site for the V(IV)/V(V) reaction but wetting of the catalyst layer is of high importance.
Multiwalled Carbon Nanotube Modified Electrodes for the Adsorptive Stripping Voltammetric Determination and Quantification of Curcumin in Turmeric
Authors: Chaisiwamongkhol Korbua , Ngamchuea Kamonwad , Batchelor‐McAuley Christopher , Compton Richard G. 
Published: December 2016

AbstractA sensitive electrochemical method for the determination and quantification of curcumin using adsorptive stripping voltammetry (AdsSV) at a multiwalled carbon nanotube modified basal plane pyrolytic graphite electrode (MWCNT‐BPPG electrode) is presented exploiting the high surface area of the latter. Next the voltammetric behaviour of curcumin on the modified electrode is examined and AdsSV shown to be a sensitive method for quantifying curcumin. The adsorption of curcumin on the electrode surface is evidenced to follow a Langmuir adsorption isotherm. Linear calibration for curcumin in the range of 2–100 μM was obtained with a detection limit of 0.45 μM and a limit of quantification of 1.49 μM. For application to real samples of turmeric, a one‐step sample preparation in ethanol has developed providing a simple and rapid extraction procedure. The MWCNT‐BPPG electrode with AdsSV allowed the determination of curcumin equivalent in turmeric powder sample with recoveries in the range of 92–108 %. This facile and fast method will be useful for monitoring the quality of curcumin containing in commercial turmeric products.
Gold Nanoparticles Stabilized in β‐Cyclodextrin and Decorated with Laccase Applied in the Construction of a Biosensor for Rutin
Authors: Brugnerotto Patricia , Silva Tânia Regina , Brondani Daniela , Zapp Eduardo , Vieira Iolanda Cruz 
Published: December 2016

AbstractThis paper describes the synthesis and characterization of gold nanoparticles stabilized in β‐cyclodextrin (AuNP‐CD), which were applied as a platform in the immobilization of laccase (LAC). The AuNP‐CD‐LAC were used in the construction of a new biosensor for rutin determination by square‐wave voltammetry (SWV). Under optimized conditions, the calibration curve showed a linear range for rutin of 0.30 to 2.97 μmol L−1, with a limit of detection of 0.17 μmol L−1. The biosensor demonstrated satisfactory repeatability and electrode‐to‐electrode repeatability (with relative standard deviations of 5.6 and 6.0 %, respectively) and good stability. The biosensor was successfully applied in the determination of rutin in different pharmaceutical samples.
Temporal monitoring of perfluorooctane sulfonate accumulation in aquatic biota downstream of historical aqueous film forming foam use areas
Authors: Lanza Heather A. , Cochran Rebecca S. , Mudge Joseph F. , Olson Adric D. , Blackwell Brett R. , Maul Jonathan D. , Salice Christopher J. , Anderson Todd A. 
Published: December 2016

Abstract

Perfluoroalkyl substances (PFAS) have recently received increased research attention, particularly concerning aquatic organisms and in regions of exposure to aqueous film forming foams (AFFFs). Air Force bases historically applied AFFFs in the interest of fire training exercises and have since expressed concern for PFAS contamination in biota from water bodies surrounding former fire training areas. Six PFAS were monitored, including perfluorooctane sulfonate (PFOS), in aquatic species from 8 bayou locations at Barksdale Air Force Base in Bossier City, Louisiana (USA) over the course of 1 yr. The focus was to evaluate temporal and spatial variability in PFAS concentrations from historic use of AFFF. The PFOS concentrations in fish peaked in early summer, and also increased significantly downstream of former fire training areas. Benthic organisms had lower PFOS concentrations than pelagic species, contrary to previous literature observations. Bioconcentration factors varied with time but were reduced compared with previously reported literature values. The highest concentration of PFOS in whole fish was 9349 ng/g dry weight, with 15% of samples exceeding what is believed to be the maximum whole fish concentration reported to date of 1500 ng/g wet weight. Further studies are ongoing, to measure PFAS in larger fish and tissue-specific partitioning data to compare with the current whole fish values. The high concentrations presently observed could have effects on higher trophic level organisms in this system or pose a potential risk to humans consuming contaminated fish. Environ Toxicol Chem 2017;36:2022–2029. © 2016 SETAC
The Amyloid‐β Peptide in Amyloid Formation Processes: Interactions with Blood Proteins and Naturally Occurring Metal Ions
Authors: Wallin Cecilia , Luo Jinghui , Jarvet Jüri , Wärmländer Sebastian K. T. S. , Gräslund Astrid 
Published: December 2016

AbstractThis review describes interactions between the amyloid‐β peptide (Aβ) involved in Alzheimer's disease (AD) and endogenous metal ions and proteins, with an emphasis on future potential drug therapies and targets. AD is characterised by loss of neurons, memory, and cognitive functions, and by formation of cerebral senile plaque deposits. These plaques consist mainly of aggregated Aβ peptides. AD pathology includes a) on the molecular level imbalanced concentrations of Aβ peptides and metal ions, and formation of amyloid structures, and b) on the physiological level a combination of inflammatory responses and oxidative stress effects causing neuronal death. Interestingly, certain blood proteins and metal ions can affect the Aβ amyloid aggregation process. These interactions are the topics of the present review. A deeper understanding of these interactions could facilitate new therapeutic strategies against AD. Previous therapeutic approaches and trials are also briefly described.
Structure and Stability of GaS Fullerenes and Nanotubes
Authors: Enyashin Andrey N. , Brontvein Olga , Seifert Gotthard , Tenne Reshef 
Published: December 2016

AbstractRecently, polyhedral; octahedral fullerene‐like structures and cylindrical nanotubes of gallium sulfide have been produced in far from equilibrium conditions using a high power solar synthesis and Pb as growth promoter. Their exact atomistic structure and their formation path remain unknown. Here, the models of fullerenes and nanotubes are designed for both stable β‐ and metastable γ‐polymorphs of GaS. Their stability and electronic properties were investigated as a function of both the morphology and size using density‐functional tight‐binding method. The results manifest that, construction principles for GaS fullerenes are different from those for “classical” dichalcogenide fullerenes. In contrast to the bulk, the kinetic stability of fullerene‐like structures of the γ‐GaS phase is found to be larger, than that for β‐GaS which is ascribed to a sterical specificity of intersected γ‐GaS layers. We predict that, the γ‐GaS phase should arise at least as an intermediate state during the synthesis of polyhedral GaS nanoparticles. Notwithstanding the polymorphic type, the size and the morphology of GaS nanostructures, they are all semiconductors. Finally, the possible composition and electronic properties of Pb||GaS interface within the Pb@GaS nanoparticles are discussed.
Characterization of Sox9‐overexpressing human umbilical cord blood‐derived mesenchymal stem cells‐based engineered cartilage both in vitro and in vivo
Authors: Li Xiao‐Li , Zhang Jun , Luo Hua‐Nan , Zhao Xiao‐Yan , Zhang A‐Ling , Wang Zheng‐Hui 
Published: December 2016

AbstractThe source of seed cells is a critical factor for tissue engineering. The goal of this study was to evaluate the chondrogenesis of Sox9‐overexpressing human umbilical cord mesenchymal stem cells (hUCMSCs) seeded onto bone matrix gelatin (BMG)/fibrin hybrid scaffolds both in vitro and in vivo. hUCMSCs were stably transfected with Sox9‐expressing plasmid and grown on the three‐dimensional BMG/fibrin hybrid scaffold for 8 weeks. Scanning electron microscopy and histochemistry were performed. The hUCMSC‐loaded scaffolds were implanted into the subcutaneous layer of immunocompetent rats and chondrogenesis and host immune responses were monitored for 8 weeks. We found that hUCMSCs spread well and proliferated from 2 weeks after culturing. They produced abundant glycosaminoglycans and collagen II. At 8 weeks after implanting into rats, the hUCMSCs on the scaffolds formed cartilage‐like tissue and displayed positive staining for toluidine blue, safranin O, Masson's trichrome, and collagen II. No significant changes in serum levels of lgG, lgA, lgM, C3, and C4 were observed after implantation of the hUCMSC‐loaded scaffolds. Xenogeneic implantation of Sox9‐overexpressing hUCMSCs embedded in the BMG/fibrin scaffolds promotes the formation of cartilage‐like tissue without inducing evident host immune response. Therefore, Sox9‐overexpressing hUCMSCs represent a promising cell candidate for cartilage tissue engineering. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1150–1155, 2017.
Preparation of a calcium carbonate‐based bone substitute with cinnamaldehyde crosslinking agent with potential anti‐inflammatory properties
Authors: Dewi Anne Handrini , Ana Ika Dewi , Jansen John 
Published: December 2016

AbstractCalcium sulfate (CS), also known as POP (Plaster of Paris) is a self‐setting, biocompatible, and osteoconductive biomaterial with a long history for the treatment of skeletal defects. However, CS cements show a too fast resorption rate and are unable to provide a long‐term 3D framework during the osteogenesis process. In our previous studies, it was found that the incorporation of CaCO3and CaCO3hydrogel provided enhanced mechanical and degradation properties of POP composites. Furthermore, it was also found that the use of cinnamaldehyde to crosslink CaCO3hydrogel may have some advantages, for example to crosslink the hydrogel and to act as anti‐inflammatory control agent. The objective of the current study was to evaluate the effect of adding cinnamaldehyde crosslinked CaCO3hydrogel into POP on the diametral tensile strength, weight loss, age swelling, degradation, cinnamaldehyde release, and porosity. The following composites were prepared: POP/HCin‐025 (25% addition of hydrogel microsphere) and POP/HCin‐050 (50% addition of hydrogel microsphere). The composites were assessed on their diametral tensile strength, weight loss of the POP composite, age swelling, degradation of the hydrogel CaCO3, cinnamaldehyde release, and porosity, as well as XRD‐patterns and FT‐IR spectra. It was confirmed from the study that incorporation of cinnamaldehyde into CaCO3hydrogel system significantly increased the mechanical strength of the POP composite. Weight loss, swelling ratio in both acid to neutral pH, and biodegradability of the POP composites were controllable by the addition of cinnamaldehyde‐CaCO3hydrogel. Moreover, the cinnamaldehyde incorporated into the hydrogel was proven to be released in a controlled manner. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 1055–1062, 2017.
Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice
Authors: Ramos-Junior Erivan S , Leite Gisele A , Carmo-Silva Cecilia C , Taira Thaise M , Neves Karla B , Colón David F , da Silva Lea AB , Salvador Sergio L , Tostes Rita C , Cunha Fernando Q , Fukada Sandra Y 
Published: December 2016

ABSTRACT

Chemerin is an adipokine that regulates adipogenesis and metabolic functions of mature adipocytes mainly through the activation of chemokine-like receptor 1 (CMKLR1). Elevated levels of chemerin have been found in individuals with obesity, type 2 diabetes, and osteoporosis. This adipokine was identified as an inflammatory and metabolic syndrome marker. Considering that the association between metabolic syndrome and bone health remains unclear, the present study aimed to clarify the role of chemerin in the pathophysiology of bone loss induced by dyslipidemia, particularly modulating osteoclastogenesis. In vitro analyses showed a downregulation of CMKLR1 at the early stage of differentiation and a gradual increase at late stages. Strikingly, chemerin did not modify osteoclast differentiation markers or osteoclast formation; however, it increased the actin-ring formation and bone resorption activity in mature osteoclasts. The increased bone resorption activity induced by chemerin was effectively inhibited by CMKLR1 antagonist (CCX832). Chemerin boosting mature osteoclast activity involves ERK5 phosphorylation. Moreover, two models of dyslipidemia (high-fat diet [HFD]-treated C57/BL6 and db/db mice) exhibited significantly increased level of chemerin in the serum and gingival tissue. Morphometric analysis showed that HFD-treated and db/db mice exhibited increased alveolar bone loss compared to respective control mice, which was associated with an up-regulation of chemerin, CMKLR1 and cathepsin K mRNA expression in the gingival tissue. The treatment of db/db mice with CCX832 effectively inhibited bone loss. Antagonism of chemerin receptor also inhibited the expression of cathepsin K in the gingival tissue. Our results show that chemerin not only increases osteoclasts activity in vitro, but also that increased level of chemerin in dyslipidemic mice plays a critical role in bone homeostasis. © 2016 American Society for Bone and Mineral Research.
The ripple effect: A spillover model of the detrimental impact of work–family conflict on job success
Authors: Wayne Sandy J. , Lemmon Grace , Hoobler Jenny M. , Cheung Gordon W. , Wilson Morgan S. 
Published: December 2016

SummaryExploring the role of both the employee and supervisor, we tested a model of how cognition‐based work‐to‐family conflict manifests itself in the workplace, impacting employee job success. Based on conservation of resources theory and the concept of loss spirals, we hypothesized that when an employee's work interferes with family demands, the resulting work‐to‐family conflict spills over to the work domain via employee emotional exhaustion. We further argued that the behavioral manifestation of employee emotional exhaustion in the workplace is low employee engagement, as assessed by the supervisor. Drawing on signaling theory, we proposed that supervisor assessments of employee engagement are related to promotability, performance ratings, and salary. Work scheduling autonomy, as a boundary condition, is examined as a resource that attenuates these relationships. Data collected from 192 employee–supervisor dyads of a Fortune 1000 company, as well as performance ratings and salary obtained from company records 9 months later, indicated support for our conceptual model. Future research examining employee work–family conflict and job outcomes is discussed. Copyright © 2016 John Wiley & Sons, Ltd.
Evaluation of the added value of a high‐resolution regional climate model simulation of the South Asian summer monsoon climatology
Authors: Karmacharya J. , Jones R. , Moufouma‐Okia W. , New M. 
Published: December 2016

ABSTRACTThe South Asian summer monsoon (SASM) is a continental scale weather phenomenon, which fluctuates at a range of temporal and spatial scales. Although majority of global climate models are broadly able to simulate the large scale characteristics of the SASM, they generally have major deficiencies such as constraints in reproducing observed mean precipitation. It is generally anticipated that higher resolution regional climate models (RCMs) would be able to simulate an improved mean state owing to their capacity to better simulate fine temporal and spatial scale features and variability. Here, we analyse SASM simulations using a contemporary Hadley Centre RCM, forced by ERA‐Interim reanalysis and observed sea surface temperature, at medium (0.44°) and high (0.11°) horizontal resolutions. Evaluation of the results show that, compared to the medium resolution RCM, the high resolution RCM is able to better resolve the interaction of the low level monsoon flow with the Himalayan orography leading to added value in simulating many aspects of SASM precipitation such as the seasonal mean, relative frequency distribution of daily precipitation, and various metrics of precipitation extremes. In contrast to many previous studies, maximum added value is note along the Indo‐Gangetic plain rather than over the complex Himalayas, and the added values of up to 5 mm day−1 and 50 days are noted for mean precipitation and number of wet days, respectively over the region. Similarly, added values of up to 15 and 3 mm day−1 are noted for 95th percentile of daily precipitation and simple daily intensity index, respectively over central India and the Himalayan range. These results suggest that higher resolution RCMs have the potential to add more value when downscaling global climate model climate change projections.
An adaptive generation method for electrophoretic display driving waveform design
Authors: Duan Fei‐Bo , Bai Peng‐Fei , Henzen Alex , Shui Ling‐Ling , Tang Biao , Zhou Guo‐Fu 
Published: December 2016

AbstractElectrophoretic display (EPD) technology is attractive when used for reading devices such as e‐paper because of its paper‐like appearance. EPD driving is more complex than other display technologies such as liquid crystal display or organic light emission diode because the driving result of a pixel strongly depends on the initial display state. The particle size and distribution in the EPD film may vary, even if the initial state is the same. Therefore, the display devices vary between different manufacturing batches. Furthermore, different display modes such as videos, pictures or documents need different driving waveforms to achieve an optimal result. EPD manufacturers need to build a customized driving waveform for every manufacturing batch. This is very inconvenient if new applications on EPD are to be developed. And the workload is huge. In this work, an adaptive method is described for automatically creating EPD driving waveforms to fit different conditions. The central idea of this method is generally adjusting the driving time and the voltage state after getting the feedback from a measurement model. In this method, a new driving waveform is used to reduce refresh time and visual flicker. The experimental results show that the proposed approach can automatically and adaptively generate an EPD driving waveform with reasonable quality.