bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multicriteria optimization approach to deploy humanitarian logistic operations integrally during floods
Authors: Mejia‐Argueta Christopher , Gaytán Juan , Caballero Rafael , Molina Julián , Vitoriano Begoña 
Published: January 2018

AbstractThis paper addresses frequent and foreseeable floods in the short‐term preparedness of an imminent event using a multicriteria optimization model integrated with a geographical information system to simulate flood levels, determine the best strategies, and update information. The proposed model takes into account the four main relief operations: location of emergency facilities (i.e., distribution centers, shelters, and meeting points), prepositioning of humanitarian aid, evacuation, and distribution of humanitarian aid. Three criteria are considered in the formulation to minimize: the maximum evacuation flow‐time, the maximum distribution flow‐time, and total cost of relief operations. The approximation to the efficient frontier is built using multiobjective programming through the use of commercial software. The usefulness and robustness of the model are verified using data from one of the worst Mexican floods considering various flood levels created from three key elements in humanitarian logistics. The strategies provided by the proposed methodology are compared with those implemented by the Mexican authorities during the studied disaster.
Influence of calcium additions on the compressive strength and microstructure of alkali‐activated ceramic sanitary‐ware
Authors: Reig Lucía , Soriano Lourdes , Tashima Mauro M. , Borrachero María V. , Monzó Jose , Payá Jordi 
Published: January 2018

AbstractThe ceramic sanitary‐ware market generates large amounts of waste, both during the production process and due to construction and demolition practices. In this paper, the effect of different amounts and calcium sources (calcium hydroxide Ca(OH)2, calcium aluminate cement CAC, Portland cement PC) on the alkaline activation of ceramic sanitary‐ware waste (CSW) was assessed. Blended samples were activated with NaOH and sodium silicate solutions and cured for 3 and 7 days at 65°C. The maximum amount of calcium source‐type added to the system varied according to its influence on the compactability of the mortars.CSW was physico‐chemically characterized and the compressive strength development of activated samples was assessed on the mortars. The nature of the reaction products was analyzed in pastes, by X‐ray diffraction, thermogravimetric analysis, infrared spectroscopy and microscopic studies. The results show a great positive influence with the addition of moderate amounts of Ca(OH)2, PC and CAC on the mechanical properties. Among the typical hydrates usually observed in plain water‐hydrated PC or CAC, only AH3 and a small amount of C3AH6 were identified in the alkali‐activated CSW/CAC blended pastes, which indicates that Al and Ca from PC, CAC and Ca(OH)2 are taken up in the newly formed (N,C)‐A‐S‐H or C‐A‐S‐H gels.
Low‐temperature synthesis of uranium monocarbide by a Pechini‐type in situ polymerizable complex method
Authors: Guo Hangxu , Wang Jieru , Bai Jing , Cao Shiwei , Chen Denglei , Sun Yalou , Yin Xiaojie , Tian Wei , Tan Cunmin , Huang Qing , Qin Zhi , Deng Qihuang 
Published: January 2018

AbstractUranium monocarbide (UC) was successfully synthesized by the Pechini‐type in situ polymerizable complex technique (IPC) with the organic matter as the only carbon source. In the aqueous process, a mixture of citric acid (CA) and mannitol withwas polymerized to form a spongy‐like organic polymeric precursor without any precipitations. The structural evolution and formation mechanism of the precursor were investigated using XRD, DSC‐TG, SEM (EDX), TEM, and FT‐IR. XRD results demonstrated that UC was obtained with the/mannitol/CA molar ratios of 1.0/0.3/1.0 at a low temperature of 1400°C. SEM and TEM analyses revealed that the UO2nanoparticles were uniformly distributed in the carbon matrix to form UO2/C nanocomposites, and submicrometer‐sized ellipsoidal UC particles cemented together. FT‐IR showed that a‐CA chelated structure was firstly obtained, achieving the molecular scale mixing of uranium and C. Then the in situ charring guaranteed the intimate contact of UO2and C, leading to a low reaction temperature in carbothermal reduction owing to a short diffusion distance.
Would you like to add a weight after this blood pressure, doctor? Discovery of potentially actionable associations between the provision of multiple screens in primary care
Authors: Kalia Sumeet , Greiver Michelle , Zhao Xu , Meaney Christopher , Moineddin Rahim , Aliarzadeh Babak , Grunfeld Eva , Sullivan Frank 
Published: January 2018

AbstractRationale, aims, and objectiveGuidelines recommend screening for risk factors associated with chronic diseases but current electronic prompts have limited effects. Our objective was to discover and rank associations between the presence of screens to plan more efficient prompts in primary care.MethodsRisk factors with the greatest impact on chronic diseases are associated with blood pressure, body mass index, waist circumference, glycaemic and lipid levels, smoking, alcohol use, diet, and exercise. We looked for associations between the presence of screens for these in electronic medical records. We used association rule mining to describe relationships among items, factor analysis to find latent categories, and Cronbach α to quantify consistency within latent categories.ResultsData from 92 140 patients in or around Toronto, Ontario, were included. We found positive correlations (lift >1) between the presence of all screens. The presence of any screen was associated with confidence greater than 80% that other data on items with high prevalence (blood pressure, glycaemic and lipid levels, or smoking) would also be present. A cluster of rules predicting the presence of blood pressure were ranked highest using measures of interestingness such as standardized lift. We found 3 latent categories using factor analysis; these were laboratory tests, vital signs, and lifestyle factors; Cronbach α ranged between .58 for lifestyle factors and .88 for laboratory tests.ConclusionsAssociations between the provision of important screens can be discovered and ranked. Rules with promising combinations of associated screens could be used to implement data driven alerts.
Skeletogenesis in the Persian sturgeon Acipenser persicus and its correlation with gene expression of vitamin K‐dependent proteins during larval development
Authors: Eshaghzadeh H. , Akbarzadeh A. , Yarmohammadi M. , Gisbert E. 
Published: January 2018

The present study describes morphological development of the skeleton in the Persian sturgeon Acipenser persicus and discusses the hypothesis that expression of genes encoding vitamin K‐dependent proteins (VKDP) might be correlated with the mineralization of skeletal tissues during early development in sturgeons. Results showed that development of cartilage started just after hatching (mean ± S.D., 10·9 ± 0·7 mm in total length, LT) in the head and notochord, whereas the first signs of mineralization occurred in the dentary and in the dermopalatine and palatopterygoid elements of the upper jaw, coinciding with the onset of exogenous feeding (20·1 ± 1·5 mm LT). All branchial arch elements developed between 19·3 and 22·3 mm LT, whereas mineralization was only observed in tooth plates associated with the hypobranchial 1 and gill rakers at 20·8 ± 1·5 mm LT and 48·4 ± 6·4 mm LT, respectively. Quantitative real‐time PCR showed that transcripts of VKDP genes including bone Gla protein (bgp), matrix Gla protein (mgp) and Gla rich protein (grp) genes were significantly up‐regulated during the transition to exogenous feeding, supporting hypotheses about relevance of the above‐mentioned genes in chondrogenesis at early developmental stages. The strong mineralization of skeletal elements from 21·5 to 27·3 mm LT (20 days post hatch) was in accordance with the maximal levels of bgp, mgp and grp expression indicating a correlation between development of the skeleton and the expression of VKDP genes. These data are important for evaluating A. persicus larval quality, understanding the influence of rearing biotic and abiotic factors on skeletogenesis and recognizing the occurrence of skeletal deformities in this species.
Roles of water quality and disinfectant application on inactivation of fish pathogenic Streptococcus agalactiae with povidone iodine, quaternary ammonium compounds and glutaraldehyde
Authors: Mon‐on N , Surachetpong W , Mongkolsuk S , Sirikanchana K 
Published: January 2018

AbstractStreptococcosis is an important bacterial disease in Nile tilapia causing severe economic losses to tilapia aquaculture worldwide. The effects of water quality (low‐ [LS] and high‐level [HS] soiling, to mimic clean or dirty surface conditions and temperatures) and disinfectant application (diluted concentrations and exposure time) were characterized on the inactivation of Streptococcus agalactiae isolated from diseased tilapia. Five isolates were tested against three commercial disinfectant products with the main ingredients being povidone iodine (Anidine 100™; AD), benzalkonium chloride (Better BKC 80%™; BKC 80), and a mixture of quaternary ammonium compounds and glutaraldehyde (Chloraldehyde™; CR). CR demonstrated highest efficacy to S. agalactiae inactivation, followed by BKC 80 and AD, respectively. Higher‐level soiling, low temperature, diluted concentrations and short exposure time all decreased the disinfectant efficacy. CR and BKC 80 provided more than 5‐log inactivation at 1‐min exposure at 20°C under HS conditions, and also with ten‐fold‐diluted concentrations at 60‐min exposure time at 30°C. However, AD required 10‐min exposure to effectively remove bacteria under LS conditions at 30°C. The results could facilitate aquaculture management planning that leads to operating cost reductions and improvements in biosecurity.
Efficacy of Citrilow and Cecure spray wash on prevalence of aerobic and Enterobacteriaceae bacteria/gram‐negative enteric bacilli and cattle hide quality
Authors: Long Wilbert , Sarker Majher I. , Marsico Ryan , Ulbrich Lindsey , Latona Nicholas P. , Muir Zerlina , Liu Cheng‐Kung 
Published: January 2018

AbstractThis study investigated spray wash treatments independently with Citrilow or Cecure for their effects on microbial concentrations and leather quality. Spray washing with Citrilow reduced aerobic mesophilic recovery by 2.42–2.78 log cycles 2.78–2.95 log cycles, and 3.32–3.72 log cycles on the belly, belly, and butt regions, respectively. After washing with Citrilow, Enterobacteriaceae/related gram‐negative enteric bacilli (ENT/gnEB) recovery counts reduced by, 2.14–2.57 log cycles, 3.06–4.08 log cycles, and 4.65–4.99 log cycles on the belly, head, and butt regions, respectively. Cecure significantly lowered aerobic bacterial levels on the belly, head, and butt regions by 6.00–6.12 log cycles, 1.40–1.65 log cycles, and 4.26–3.60 log cycles, respectively. Washing with Cecure significantly lowered ENT/gnEB counts by 3.65–3.01 log cycles and 2.17–3.17 log cycles on belly and butt regions. Subjective testing, grain structure analyses, and mechanical properties of leather made from fresh hides after Citrilow or Cecure treatments revealed no difference between the treatment and their corresponding controls.Practical applicationsThe purpose of this study is to investigate the ability of two antibiotics (Citrilow and Cecure) to reduce bacteria on the outer haired surface of cattle hides which serves as a potential source of cross‐contamination of pathogens to beef. In addition, while reducing probability of cross‐contamination during cattle processing, the quality of the byproducts need to be insured. In the cattle industry, antimicrobials and surfactants applied must be food safe and limit damage to the animal byproducts, in the case of this study hides which are used to produce leather. The results from this study may be beneficial for meat processing plants, hide preparers and leather manufacturers to identify antimicrobials that may limit bacterial cross‐contamination which can lead to food related illnesses while insuring the quality of one of the cattle industries main byproducts.
Interleukin‐34 levels in gingival crevicular fluid and plasma in periodontal health and disease with and without type‐2 diabetes mellitus
Authors: Guruprasad C. N. , Pradeep A. R. 
Published: January 2018

AbstractAimThe aim of the present study was to evaluate and correlate the levels of interleukin‐34 (IL‐34) in gingival crevicular fluid (GCF) and plasma in chronic periodontitis (CP) patients with and without type‐2 diabetes mellitus (DM).MethodsA total of 175 patients were divided into five groups: (a) group I had 35 periodontally‐healthy patients; (b) group II had 35 chronic gingivitis patients; (c) group III had 35 CP patients without type‐2 DM; (d) group IV had 35 CP patients with type‐2 DM; and (e) group V had 35 type‐2 DM patients without CP. The GCF and plasma levels of IL‐34 were quantified using enzyme‐linked immunosorbent assay. Clinical and systemic parameters, such as gingival index, probing pocket depth, clinical attachment loss, and glycated hemoglobin levels, were evaluated.ResultsThe mean IL‐34 concentration in GCF and plasma was highest for group IV, followed by groups III, V, and II, and lowest in group I. The difference between them was statistically significant (P < .05). There was a positive correlation between IL‐34 concentration in GCF and plasma in the study groups, with the exception of group I, for which there was a negative correlation.ConclusionIL‐34 can be considered a possible GCF and plasma inflammatory biomarker of periodontal disease progression and DM.
Low performance on mathematical tasks in preschoolers: the importance of domain‐general and domain‐specific abilities
Authors: Costa H. M. , Nicholson B. , Donlan C. , Van Herwegen J. 
Published: January 2018

AbstractBackgroundDifferent domain‐specific and domain‐general cognitive precursors play a key role in the development of mathematical abilities. The contribution of these domains to mathematical ability changes during development. Primary school‐aged children who show mathematical difficulties form a heterogeneous group, but it is not clear whether this also holds for preschool low achievers (LAs) and how domain‐specific and domain‐general abilities contribute to mathematical difficulties at a young age. The aim of this study was to explore the cognitive characteristics of a sample of preschool LAs and identify sub‐types of LAs.Methods81 children were identified as LAs from 283 preschoolers aged 3 to 5 years old and were assessed on a number of domain‐general and domain‐specific tasks.ResultsCluster analysis revealed four subgroups of LAs in mathematics: (1) a weak processing sub‐type; (2) a general mathematical LAs sub‐type; (3) a mixed abilities sub‐type; and (4) a visuo‐spatial deficit sub‐type. Whilst two of the groups showed specific domain‐general difficulties, none showed only domain‐specific difficulties.ConclusionsCurrent findings suggest that preschool LAs constitute a heterogeneous group and stress the importance of domain‐general factors for the development of mathematical abilities during the preschool years.
Medication‐related osteonecrosis of the jaw – a current review
Authors: Domah F. , Shah N. , Domah J. , Shah R. 
Published: January 2018

AbstractAimThis study was aimed to discuss different classes of antiresorptive agents and their modes of action, to review the proposed mechanisms in the pathophysiology of osteonecrosis development and to analyse the prevention and the management of medication‐related osteonecrosis of the jaw.Materials and methodsThree databases were searched for relevant articles: PubMed, Ovid and Dentistry and Oral Sciences Source. Current literature consists mainly of case series, case reports and expert body opinions.DiscussionThe repertoire of antiresorptive medication keeps expanding as novel drugs are being introduced. The exact pathway that leads to the development of osteonecrosis remains to be elucidated, but different mechanisms have been put forward. An attempt at staging has been made, and treatment guidelines have been drawn but opinions remain divided. New treatments are being trialled; however, evidence is lacking.
Temporal and Spatial Quantification of Pain‐ Related Small Fiber Functionality Assessed Using Laser Speckle Contrast Analysis
Authors: Unal‐Cevik Isin 
Published: January 2018

AbstractBackgroundThis study aimed to establish a practical method for assessing pain symptomatology and develop criteria for quantifying small fiber functions using laser speckle contrast analysis (LASCA).MethodsAxon flare responses, which reflect small fiber functions, were induced either by histamine or capsaicin applied to the volar surface of the skin of the left forearm. To inhibit small fiber function, local anesthetic cream was applied to the skin of right forearm. The effects on pain symptomatology (severity/timing) and axon flare responses (temporal/spatial characteristics) were measured using LASCA. To highlight the clinical relevance, this method was applied to 3 different types of patients with small fiber dysfunction.ResultsForty‐four forearms of 22 healthy volunteers were tested. Eutectic mixture local anesthetic cream reduced the severity and duration of pain, abolishing or prolonging the latency to reach 3‐fold higher levels of basal skin microcirculation levels, and decreasing the area and intensity of flare responses. There were positive correlations between pain symptomatology and flare response characteristics in the control forearm. Similar results were confirmed in neuropathic pain patients.ConclusionsPain‐related small fiber functions and symptomatology (two‐in‐one method) can be assessed via histamine‐ or capsaicin‐evoked axon flare responses in as little as 15 minutes. The reduction of small fiber functions are characterized by decrease in flare size/intensity at 5 minutes after stimulation and prolongation/abolishment of the latency to reach 3‐fold higher levels of baseline skin microcirculation. LASCA may be applied in the clinic to aid early diagnosis, monitor disease progression, and objectively assess treatment efficacy in patients with neuropathic pain.
Two citrate transporters coordinately regulate citrate secretion from rice bean root tip under aluminum stress
Authors: Liu Mei Ya , Lou He Qiang , Chen Wei Wei , Piñeros Miguel A. , Xu Jia Meng , Fan Wei , Kochian Leon V. , Zheng Shao Jian , Yang Jian Li 
Published: January 2018

AbstractAluminum (Al)‐induced organic acid secretion from the root apex is an important Al resistance mechanism. However, it remains unclear how plants fine‐tune root organic acid secretion which can contribute significantly to the loss of fixed carbon from the plant. Here, we demonstrate that Al‐induced citrate secretion from the rice bean root apex is biphasic, consisting of an early phase with low secretion and a later phase of large citrate secretion. We isolated and characterized VuMATE2 as a possible second citrate transporter in rice bean functioning in tandem with VuMATE1, which we previously identified. The time‐dependent kinetics of VuMATE2 expression correlates well with the kinetics of early phase root citrate secretion. Ectopic expression of VuMATE2 in Arabidopsis resulted in increased root citrate secretion and Al resistance. Electrophysiological analysis of Xenopus oocytes expressing VuMATE2 indicated VuMATE2 mediates anion efflux. However, the expression regulation of VuMATE2 differs from VuMATE1. While a protein translation inhibitor suppressed Al‐induced VuMATE1 expression, it releases VuMATE2 expression. Yeast one‐hybrid assays demonstrated that a previously identified transcription factor, VuSTOP1, interacts with the VuMATE2 promoter at a GGGAGG cis‐acting motif. Thus, we demonstrate that plants adapt to Al toxicity by fine‐tuning root citrate secretion with two separate root citrate transport systems.
Unexpected impact of esterification on the antioxidant activity and (photo)stability of a eumelanin from 5,6‐dihydroxyindole‐2‐carboxylic acid
Authors: Micillo Raffaella , Iacomino Mariagrazia , Perfetti Marco , Panzella Lucia , Koike Kenzo , D'Errico Gerardino , d'Ischia Marco , Napolitano Alessandra 
Published: January 2018

SummaryTo inquire into the role of the carboxyl group as determinant of the properties of 5,6‐dihydroxyindole melanins, melanins from aerial oxidation of 5,6‐dihydroxyindole‐2‐carboxylic acid (DHICA) and its DHICA methyl ester (MeDHICA) were comparatively tested for their antioxidant activity. MALDI MS spectrometry analysis of MeDHICA melanin provided evidence for a collection of intact oligomers. EPR analysis showed g‐values almost identical and signal amplitudes (ΔB) comparable to those of DHICA melanin, but spin density was one order of magnitude higher, with a different response to pH changes. Antioxidant assays were performed, and a model of lipid peroxidation was used to compare the protective effects of the melanins. In all cases, MeDHICA melanin performed better than DHICA melanin. This capacity was substantially maintained following exposure to air in aqueous buffer over 1 week or to solar simulator over 3 hr. Different from DHICA melanin, MeDHICA melanin was proved to be fairly soluble in different water‐miscible organic solvents, suggesting its use in dermocosmetic applications.
Development of Cotton Fabrics with Durable UV Protective and Self‐cleaning Property by Deposition of Low TiO2 Levels through Sol–gel Process
Authors: Mishra Anu , Butola Bhupendra Singh 
Published: January 2018

AbstractIn this article, the deposition of TiO2 on cotton fabric using sol–gel technique has been described. Various process routes (pad‐dry‐cure, pad‐dry‐hydrothermal and pad‐dry‐solvothermal) were examined to impart a stable coating of TiO2 on fabric. The role of precursor concentration, process temperature and time of treatment were studied to aim at a wash durable, UV protective and self‐cleaning property in the treated fabric. EDX and ICP‐MS techniques were used to examine the add‐on percentage of TiO2 on cotton fabrics treated via different routes. It has been found that the TiO2 remains largely amorphous and nondurable if it is given a short thermal treatment. To convert the deposited TiO2 to its anatase crystal form, a prolonged hydrothermal treatment for at least 3 h needs to be given. TiO2 deposition levels of less than 0.1% were found to be effective in imparting reasonable degree of UV protection and self‐cleaning property to the cotton fabric. The self‐cleaning ability of the treated fabric against coffee stain was also studied and was found to be related to the process route and the deposition levels of TiO2.