bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fabrication of a Paper‐Based Turn‐Off Fluorescence Sensor for Cu2+Ion from a Pyridinium Porphyrin
Authors: Prabphal Jutamat , Vilaivan Tirayut , Praneenararat Thanit 
Published: January 2018

AbstractA cationic porphyrin, 5,10,15,20‐tetrakis(1‐methyl‐4‐pyridinio)porphyrin tetraiodide (TMPyP) was reported herein to exert selective, turn‐off fluorescence when complexed with Cu2+ion. Although discernible spectroscopic changes of charged porphyrins with various metal ions were previously utilized as colorimetric sensors, the application of fluorescence quenching of charged porphyrins with Cu2+ion has never been investigated in much detail before. Coupled with the ease of synthesis, the finding led to a construction of a simple paper‐based sensor for Cu2+with good selectivity and sensitivity, with a limit of detection at 0.16 ppm, which is below the recommended amount in drinking water. Notably, this performance could be achieved with the need of only a handheld UV lamp and a smartphone or a compact camera, both of which are now considered to be highly accessible. Thanks to the simplicity of all involved processes, this study highlights a unique way in creating a new practical and economical sensor for Cu2+ion.
Seismic testing and numerical analysis of Y‐shaped eccentrically braced frame made of high‐strength steel
Authors: Lian Ming , Su Mingzhou 
Published: January 2018

SummaryIn eccentrically braced frame made of high‐strength steel (HSS‐EBF), link and brace are made from conventional steel whereas other structural members use high‐strength steel. Using HSS for beams and columns in EBF can reduce steel consumption and increase economic efficiency. In this paper, one shake table test of a 1:2 scaled three‐story Y‐shaped HSS‐EBF (Y‐HSS‐EBF) specimen was carried out to study its seismic behavior underground motions with different peak ground accelerations. The dynamic properties, base shear force, displacement, and strain responses of the specimen were obtained from this test. In addition, the finite element models of two 10‐story Y‐HSS‐EBF buildings and one 10‐story conventional Y‐EBF building were evaluated for seismic effects. Nonlinear pushover and dynamic analyses were conducted to compare their seismic performance and economy. The results indicated that the specimen exhibited sufficient lateral stiffness and safety but suffered some localized damages. During the high seismic intensity earthquakes, the links of the test specimen were in inelastic to dissipate the earthquake energy, whereas other structural members remained in the elastic state. Under the same design conditions, Y‐HSS‐EBF used less steel than that of conventional Y‐EBF, which could reduce the amount of steel used in Y‐HSS‐EBF. The Y‐HSS‐EBF is a safe, dual system with reliable seismic performance.
Adjustment Dynamics of Bilateral Trade Flows: Theory and Evidence
Authors: Jung Benjamin 
Published: January 2018

SummaryIn this paper, I introduce a trade-promoting ‘invisible asset’ into the standard Krugman(1980) model of international trade. It can be interpreted as trust that accumulates as an externality in proportion to successful international transactions. I use this framework to theoretically derive a dynamic gravity equation and to discuss adjustment dynamics. I provide new evidence on adjustment rates of bilateral trade flows. On average, 23% of the gap to the steady-state trade flow are closed each year. However, dynamic regressions yield long-run trade policy effects which are comparable to static estimates.
Diaspora effects in international migration: Key questions and methodological issues
Authors: Beine Michel , Docquier Frédéric , Özden Cağlar 
Published: January 2018

Summary
This paper reviews the existing literature on the impact of migrants networks on the patterns of international migration. It covers the theoretical channels at stake in the global effect of the networks. It identifies the key issues, namely the impact on size, selection and concentration of the migration flows. The paper also reviews the empirical hurdles that the researchers face in assessing the importance of networks. The key issues concern the choice of micro vs a macro approach, the definition of a network, the access to suitable data and the adoption of econometric methods accounting for the main features of those data. Finally, the paper reports a set of estimation outcomes reflecting the main findings of the macro approach.
Remitters in Dubai
Authors: Naufal George , Vargas-Silva Carlos 
Published: January 2018

Summary
This article provides a short description of remitters in Dubai. The data comes from a remittance survey on foreign workers in the Emirate conducted in 2008. Among other findings, our results suggest that there are key differences between those remitters who live in labour camps and those living in “regular” accommodations. For example, those living in labour camps have a tendency to remit more often, but tend to remit smaller amounts. One possibility is that the lack of security in labour camps has pushed these workers to remit the money they earn as soon as possible. The article points out several other differences between the two groups of workers.
Surgical Outcomes of Primary Versus Post‐Neoadjuvant Chemotherapy Breast Conservation Surgery: A Comparative Study from a Developing Country
Authors: Agarwal Gaurav , Sonthineni Chaitra , Mayilvaganan Sabaretnam , Mishra Anjali , Lal Punita , Agrawal Vinita 
Published: January 2018

AbstractIntroductionIn India and other developing countries, breast conservation surgery (BCS) rates in breast cancer patients are low due to advanced disease at presentation and misconceptions about BCS outcomes. Many patients presenting with large or locally advanced breast cancers (LABC) can be offered post‐neoadjuvant chemotherapy (NACT) BCS, safety of which is not as well established as that of primary BCS. This retrospective study compared pathological and surgical outcome parameters in patients undergoing primary and post‐NACT BCS.MethodsAll non‐metastatic breast cancer patients undergoing BCS during 2011–2015 with 1‐year follow‐up were included. Outcome parameters in form of margin infiltration, ipsilateral breast tumor recurrence (IBTR) rates and IBTR‐free survival were compared between primary and post‐NACT BCS patients groups.ResultsOne hundred and twenty‐nine patients underwent BCS; 95 underwent primary and 34 post‐NACT BCS. Patients in both groups underwent similar multimodality treatment as per institutional protocols. Post‐NACT patients more frequently required oncoplastic volume displacement or replacement surgery (p = 0.002). Re‐excision of infiltrated margins was needed more frequently in primary BCS compared with post‐NACT BCS group (14.4 vs. 8.8%; p = 0.40). IBTR (Mean follow‐up = 30.7 months) was seen in 8.8% post‐NACT patients compared with 2.1% primary BCS (p = 0.114). IBTR‐free survival did not differ significantly between the groups in stage‐wise comparison.ConclusionPost‐NACT BCS is safe even in large tumors and LABC, though many require oncoplastic procedures for satisfactory cosmesis. In a developing country where many patients present with large breast cancers or LABC, the benefits of BCS can be offered to a majority with the help of NACT, without compromising the chances of cure.
A simulation study comparing slope model with mixed‐model repeated measure to assess cognitive data in clinical trials of Alzheimer's disease
Authors: Chen Yun‐Fei , Ni Xiao , Fleisher Adam S. , Zhou Wei , Aisen Paul , Mohs Richard 
Published: January 2018

AbstractIntroductionIn clinical trials of Alzheimer's disease, a mixed‐model repeated measure approach often serves as the primary analysis when evaluating disease progression; a slope model may be secondary.MethodsLongitudinal change from baseline (14‐item version of Alzheimer's Disease Assessment Scale–Cognitive Subscale) was simulated for treatment/placebo from multivariate normal distributions with the variance‐covariance matrix estimated from solanezumab trial data. Type I error, power, and bias were based on 18‐month treatment contrast. Sample sizes included 500 and 1000 patients/arm.ResultsThe slope model was more powerful in most scenarios. Mixed‐model repeated measure was relatively unbiased in parameter estimation. The slope model yielded unbiased estimates whenever the underlying trajectory was not detectably different from linear. Both methods led to similar type I error.DiscussionIn clinical trials of Alzheimer's disease, mixed‐model repeated measure analysis with relaxed assumptions on disease progression seems to be preferred. The slope model might be more powerful if the trajectory has little departure from linearity.
Fit Characteristics of N95 Filtering Facepiece Respirators and the Accuracy of the User Seal Check among Koreans
Authors: Huh Yu Jung , Jeong Hye Min , Lim Juhye , Park Ha Yan , Kim Min Young , Oh Hong Sang , Huh Kyungmin 
Published: January 2018

Adequate facepiece fit of N95 filtering facepiece respirators (FFRs) is crucial for optimal protection against airborne pathogens. The quantitative fit test (QNFT) pass rates of the 4 N95 FFR models commonly used in Korea were below 50%. Male sex was identified as a single independent predictive factor for QNFT pass.Infect Control Hosp Epidemiol 2018;39:104–107
Neoliberalism, Authoritarian-Populism, and the “Photo-Op Democracy” of the Publicity State: Changes to Legislative and Parliamentary Norms by the Harper Government
Authors: Brabazon Honor , Kozolanka Kirsten 
Published: January 2018

AbstractSeveral recent reports seek to evaluate the impact of former Prime Minister Stephen Harper on Canadian democracy by documenting his government's efforts to curtail established democratic processes and mechanisms for public debate. However, this article uses examples of the Harper government's changes to legislative and parliamentary norms to demonstrate that this government's efforts to curtail multi-directional public debate were importantly accompanied by efforts to amplify unidirectional communication of the government's partisan messages. The paper finds that this corresponding emphasis on communication exemplified a “photo-op” approach to democracy, which highlights points of compatibility between the seemingly contradictory authoritarian-populist “publicity state” and neoliberal democratic ideals. This research demonstrates the necessity of attention to government communication in analysis of the Harper government's impact on the Canadian public sphere. It also illustrates the pragmatic rather than doctrinaire nature of New Right politics in Canada and the affinity between neoliberal and authoritarian-populist approaches to governance.
The mental health of adolescents and pre-adolescents living with inherited arrhythmia syndromes: a systematic review of the literature
Authors: Longmuir Patricia E. , Sampson Margaret , Ham Jennifer , Weekes Makenzie , Patel Bhavika J. , Gow Robert M. 
Published: January 2018

AbstractPotentially fatal arrhythmias add to the mental health challenges of adolescence. This systematic review sought to summarise current knowledge regarding the mental health of adolescents and pre-adolescents diagnosed with inherited arrhythmia syndromes. Searches combining psychological problems with inherited cardiac arrhythmia diagnoses identified 16 studies with paediatric (<18 years) inherited arrhythmia patients. All studies were cross-sectional; 8/16 required an implantable cardioverter defibrillator. Methods were quantitative (n=11), qualitative (n=4), or mixed (n=1), with 14–100% of participants having an inherited arrhythmia syndrome. Mean/median age in 13/16 studies was 12–16 years. Patients and parents reported lower quality of life, particularly in relation to physical function, social relationships, restriction of peer activities, bodily pain, and mental and emotional health. Self-perceptions and behaviour were similar to healthy populations. Rates of anxiety and depression (15–33% of these patients) were not increased in these studies where patients were assessed 2+ years after diagnosis. Higher mental health risk occurred among patients who have a diagnosed sibling, those with cardiomyopathy, and those who report decreased quality of life. Mental health research among youth with inherited arrhythmias is extremely limited and of low quality. Data, primarily from patients 2–4 years after diagnosis or treatment with an implantable cardioverter defibrillator, indicate that quality of life may be decreased and 15–33% experience mental health issues. Future research is required to examine the mental health and quality of life of paediatric patients with inherited arrhythmia syndromes, whether or not they have an implantable cardioverter defibrillator, from time of diagnosis.
Histopathological evaluation of aortic coarctation after conventional balloon angioplasty in neonates
Authors: Atalay Atakan , Pac Aysenur , Avci Tugba , Zengin Neslihan İnci , Amac Nadide Demir , Eris Deniz , Tasoglu Irfan , Pac Mustafa 
Published: January 2018

AbstractBackgroundOptimal management strategy for native aortic coarctation in neonates and young infants is still a matter of debate. The surgical procedure, histopathologic research, and clinical outcome in 15 neonates who underwent surgery after successful balloon angioplasty is the basis of this study.MethodBetween 01 October, 2014 and 01 August, 2017, we enrolled 15 patients with native aortic coarctation for this study. These patients had complications regarding recoarctation, following balloon angioplasty intervention at our institute and other centres. Surgically extracted parts were examined histopathologically and patient’s data were collected retrospectively.ResultThe reasons for recurrence of recoarctation after balloon angioplasty are as follows: patients with higher preoperative echocardiographic gradients had recoarctation earlier, neointimal proliferation, aortic intimal fibrosis at the region of ductal insertion, and ductal residual tissue debris after balloon angioplasty. No repeat intervention was required in the 15 patients who underwent surgery followed by balloon angioplasty. Early mortality was seen in one patient after surgery. Postoperative complication in the surgical group occurred in the form of chylothorax in one patient.ConclusionIn centres in which the neonatal ICU is inexperienced, balloon angioplasty is particularly recommended. In developing neonatal clinics, balloon angioplasty, when performed on patients at their earliest possible age, delays actual corrective operation to a later date, which in turn provides less risky surgical outcomes in infants who are gaining weight, growing, and do not have any haemodynamic complaints.
Farming adaptations in the face of climate change
Authors: Som Castellano Rebecca L. , Moroney Jillian 
Published: January 2018

AbstractAgriculture is one of the most vulnerable sectors to climate change, and in many agricultural communities climate change adaptations by farmers are underway. Farmers’ beliefs about climate change and their experiences with climate change, along with a range of other factors, could influence climate change adaptation. Utilizing a framework which draws from research examining how farmers’ climate change beliefs and experiences affect their adaptation strategies, and research on farm succession and adaptation at the rural–urban interface (RUI), we ask ‘How do climate change beliefs and different farm attributes (particularly the presence of an heir and location at the RUI) affect adaptation strategies?’ Preliminary findings indicate that adaptation varies based on multiple factors, including belief in climate change, the presence of an heir, geographical location and a variety of other farm characteristics and farmer attributes.
Data analytics and parallel-coordinate materials property charts
Authors: Rickman Jeffrey M. 
Published: January 2018

AbstractIt is often advantageous to display material properties relationships in the form of charts that highlight important correlations and thereby enhance our understanding of materials behavior and facilitate materials selection. Unfortunately, in many cases, these correlations are highly multidimensional in nature, and one typically employs low-dimensional cross-sections of the property space to convey some aspects of these relationships. To overcome some of these difficulties, in this work we employ methods of data analytics in conjunction with a visualization strategy, known as parallel coordinates, to represent better multidimensional materials data and to extract useful relationships among properties. We illustrate the utility of this approach by the construction and systematic analysis of multidimensional materials properties charts for metallic and ceramic systems. These charts simplify the description of high-dimensional geometry, enable dimensional reduction and the identification of significant property correlations and underline distinctions among different materials classes.
Real-time colour hologram generation based on ray-sampling plane with multi-GPU acceleration
Authors: Sato Hirochika , Kakue Takashi , Ichihashi Yasuyuki , Endo Yutaka , Wakunami Koki , Oi Ryutaro , Yamamoto Kenji , Nakayama Hirotaka , Shimobaba Tomoyoshi , Ito Tomoyoshi 
Published: January 2018

AbstractAlthough electro-holography can reconstruct three-dimensional (3D) motion pictures, its computational cost is too heavy to allow for real-time reconstruction of 3D motion pictures. This study explores accelerating colour hologram generation using light-ray information on a ray-sampling (RS) plane with a graphics processing unit (GPU) to realise a real-time holographic display system. We refer to an image corresponding to light-ray information as an RS image. Colour holograms were generated from three RS images with resolutions of 2,048 × 2,048; 3,072 × 3,072 and 4,096 × 4,096 pixels. The computational results indicate that the generation of the colour holograms using multiple GPUs (NVIDIA Geforce GTX 1080) was approximately 300–500 times faster than those generated using a central processing unit. In addition, the results demonstrate that 3D motion pictures were successfully reconstructed from RS images of 3,072 × 3,072 pixels at approximately 15 frames per second using an electro-holographic reconstruction system in which colour holograms were generated from RS images in real time.
An optimised protocol for platelet-rich plasma preparation to improve its angiogenic and regenerative properties
Authors: Etulain Julia , Mena Hebe A. , Meiss Roberto P. , Frechtel Gustavo , Gutt Susana , Negrotto Soledad , Schattner Mirta 
Published: January 2018

AbstractAlthough platelet-rich plasma (PRP) is used as a source of growth factors in regenerative medicine, its effectiveness remains controversial, partially due to the absence of PRP preparation protocols based on the regenerative role of platelets. Here, we aimed to optimise the protocol by analysing PRP angiogenic and regenerative properties. Three optimising strategies were evaluated: dilution, 4 °C pre-incubation, and plasma cryoprecipitate supplementation. Following coagulation, PRP releasates (PRPr) were used to induce angiogenesis in vitro (HMEC-1 proliferation, migration, and tubule formation) and in vivo (chorioallantoic membrane), as well as regeneration of excisional wounds on mouse skin. Washed platelet releasates induced greater angiogenesis than PRPr due to the anti-angiogenic effect of plasma, which was decreased by diluting PRPr with saline. Angiogenesis was also improved by both PRP pre-incubation at 4 °C and cryoprecipitate supplementation. A combination of optimising variables exerted an additive effect, thereby increasing the angiogenic activity of PRPr from healthy donors and diabetic patients. Optimised PRPr induced faster and more efficient mouse skin wound repair compared to that induced by non-optimised PRPr. Acetylsalicylic acid inhibited angiogenesis and tissue regeneration mediated by PRPr; this inhibition was reversed following optimisation. Our findings indicate that PRP pre-incubation at 4 °C, PRPr dilution, and cryoprecipitate supplementation improve the angiogenic and regenerative properties of PRP compared to the obtained by current methods.
Assessing fatty acid oxidation flux in rodent cardiomyocyte models
Authors: Rech M. , Luiken J. J. F. P. , Glatz J. F. C. , van Bilsen M. , Schroen B. , Nabben M. 
Published: January 2018

AbstractThe healthy adult heart primarily relies on fatty acid oxidation (FAO) for energy production but instantaneously adapts its substrate preference in response to physiological or pathological challenges. Accurate FAO measurements are crucial to investigate early metabolic (mal)adaptations. While measurements in intact cardiomyocytes offer greater physiological relevance, current FAO protocols mainly employ cell-free systems and/or require expensive equipment. Here, we present an easy-to-use, inexpensive, and sensitive method to measure, compare and modulate FAO in various cardiomyocyte models. Basal FAO was 2-fold higher in fresh versus cultured adult rat cardiomyocytes (aRCM), while OXPHOS protein levels were maintained. Basal FAO was higher in cultured (3-fold) and fresh (8-fold) aRCM, versus widely used neonatal rat cardiomyocytes (nRCM) and mouse HL1 cardiomyocytes. Moreover, we utilized chemical and pharmacological treatments in order to modulate the FAO flux at different cellular signalling levels. Our data indicate that caution should be taken when studying metabolism in nRCM and HL1 cell models, as these display significantly lower FAO than aRCM. Accurate FAO measurement in cultured aRCM opens new avenues for studying the complex cardiomyocyte metabolic responses to mechanical, nutritional, pharmacological, and genetic manipulations.
Bacterial community in naturally fermented milk products of Arunachal Pradesh and Sikkim of India analysed by high-throughput amplicon sequencing
Authors: Shangpliang H. Nakibapher Jones , Rai Ranjita , Keisam Santosh , Jeyaram Kumaraswamy , Tamang Jyoti Prakash 
Published: January 2018

AbstractNaturally fermented milk (NFM) products are popular ethnic fermented foods in Arunachal Pradesh and Sikkim states of India. The present study is the first to have documented the bacterial community in 54 samples of NFM products viz. chhurpi, churkam, dahi and gheu/mar by high-throughput Illumina amplicon sequencing. Metagenomic investigation showed that Firmicutes (Streptococcaceae, Lactobacillaceae) and Proteobacteria (Acetobacteraceae) were the two predominant members of the bacterial communities in these products. Lactococcus lactis and Lactobacillus helveticus were the predominant lactic acid bacteria while Acetobacter spp. and Gluconobacter spp. were the predominant acetic acid bacteria present in these products.