bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vickrey auction vs BDM: difference in bidding behaviour and the impact of other-regarding motives
Authors: Flynn Niall , Kah Christopher , Kerschbamer Rudolf 
Published: November 2016

AbstractIn an experiment, we first elicit the distributional preferences of subjects and then let them bid for a lottery, either in a Becker–DeGroot–Marschak (BDM) mechanism or a Vickrey auction (VA). The standard theory predicts that altruistic subjects underbid in the VA—compared to the BDM—while spiteful subjects overbid in the VA. The data do not confirm those predictions. While we observe aggregate underbidding in the VA, the result is not driven by the choices of altruistic subjects.
Lack of association between vitamin D receptor polymorphisms ApaI (rs7975232) and BsmI (rs1544410) and osteoporosis among the Han Chinese population: A meta‐analysis
Authors: Yu Meng , Chen Guo‐Qiang , Yu Fang 
Published: November 2016

AbstractIn this study, we aimed to assess the relationship between vitamin D receptor gene polymorphisms and osteoporosis in the Han Chinese population. Articles regarding associations between vitamin D receptor polymorphisms (ApaI rs7975232 and BsmI rs1544410) and osteoporosis were retrieved from databases in November 2014. Eligible studies were tested by the Hardy–Weinberg equilibrium. The odds ratio and 95% confidence interval (95% CI) were analyzed to evaluate the strength of the associations. Pooled effect estimates were derived using a fixed‐effect model and a random‐effect model according to the heterogeneity of the test results. A subgroup analysis by study type and a sensitivity analysis based on studies that conform to the Hardy–Weinberg equilibrium and studies with postmenopausal women as participants were performed. This meta‐analysis involved 15 eligible studies including 1580 cases and 1389 controls. The pooled estimated odds ratios in the dominant and additive genetic models were 0.73 (95% CI: 0.46–1.14, p = 0.17) and 1.01 (95% CI: 0.77–1.33, p = 0.81), respectively, for rs7975232 and 1.01 (95% CI: 0.81–1.26, p = 0.91) and 1.01 (95% CI: 0.77–1.33, p = 0.92), respectively, for rs1544410. The subgroup analysis showed that regardless of the dominant or additive genetic model, the effect of pooled odds ratios for rs7975232 and rs1544410 was insignificant. The sensitivity analysis also showed that the pooled effect was not significantly changed. In conclusion, no evidence of association is apparent between polymorphisms of vitamin D receptor genes and osteoporosis risk in the Han Chinese population.
Association of MMP‐2 and MMP‐9 expression with recurrences in primary spontaneous pneumothorax
Authors: Huang Ying‐Fong , Chiu Wen‐Chin , Chou Shah‐Hwa , Su Yu‐Han , Chen Yu‐Wen , Chai Chee‐Yin , Huang Chih‐Jen , Huang Ming‐Yii , Yuan Shyng‐Shiou F. , Lee Yi‐Chen 
Published: November 2016

AbstractPrimary spontaneous pneumothorax (PSP) is a common benign problem. However, PSP recurrence is still a troublesome complication for most patients. This study intended to determine the role of matrix metalloproteinase‐2 (MMP‐2) and MMP‐9 in type II pneumocytes of patients with PSP and its relation with recurrence. Ninety‐one patients who had undergone needlescopic video‐assisted thoracoscopic surgery wedge resection of lung with identifiable blebs for PSP were included in this study. Immunohistochemical (IHC) staining was used to measure the expression of MMP‐2 and MMP‐9 in lung tissues of PSP patients. The results were further correlated with clinicopathological parameters and recurrence rates using chi‐square or Fisher's exact test. The value of MMP‐2 and MMP‐9 for overall recurrence was analyzed by univariate and multivariable Cox regression model. IHC data revealed that MMP‐2 and MMP‐9 staining was predominantly observed in type II pneumocytes of patients with PSP. We found that MMP‐2 and MMP‐9 expression in PSP, especially male PSP patients, was significantly correlated with recurrence. In the univariate and multivariate analyses, MMP‐2 and MMP‐9 were statistically significant risk factors for overall recurrence in PSP patients. Therefore, high expression levels of MMP‐2 and MMP‐9 in type II pneumocytes show a positive correlation with PSP recurrence risk. Further studies are needed to validate whether reduction of MMP‐2 and MMP‐9 expression may be a promising way for decreasing the risk of PSP recurrence in the future.
Controlling Tuberculosis in the United States: Use of Isolation and Other Measures Throughout the Country
Authors: Katz Rebecca , Vaught Andrea 
Published: November 2016

AbstractObjectivesWe sought to better understand the tools used by public health officials in the control of tuberculosis (TB).MethodsWe conducted a series of in-depth interviews with public health officials at the local, state, and federal levels to better understand how health departments around the country use isolation measures to control TB.ResultsState and local public health officials’ use of social distancing tools in infection control varies widely, particularly in response to handling noncompliant patients. Judicial and community support, in addition to financial resources, impacted the incentives and enablers used to maintain isolation of infectious TB patients.ConclusionsInstituting social distancing requires authorities and resources and can be impacted by evidentiary standards, risk assessments, political will, and community support. Awareness of these factors, as well as knowledge of state and local uses of social distancing measures, is essential to understanding what actions are most likely to be instituted during a public health emergency and to target interventions to better prepare health departments to utilize the best available tools necessary to control the spread of disease. (Disaster Med Public Health Preparedness. 2017;11:337–342)
Incidence of Hospital Norovirus Outbreaks and Infections Using 2 Surveillance Methods in Sweden
Authors: Fraenkel Carl-Johan , Inghammar Malin , Johansson P. J. Hugo , Böttiger Blenda 
Published: November 2016

OBJECTIVETo evaluate 2 different methods of surveillance and to estimate the incidence of norovirus (NoV) outbreaks in hospitals.DESIGNProspective observational study.SETTINGAll 194 hospital wards in southern Sweden during 2 winter seasons (2010–2012).METHODSClinical surveillance based on outbreak reports of 2 or more clinical cases, with symptom onset within 5 days, was compared with laboratory surveillance based on positive NoV results among inpatients. At least 2 NoV positive patients sampled within 5 days at a ward defined a cluster. Outbreak reports including at least 1 NoV positive case and clusters including at least 1 NoV positive patient with 5 or more days from ward admission to sampling were defined as NoV outbreaks.RESULTSDuring the study periods 135 NoV outbreaks were identified; 74 were identified by both clinical and laboratory surveillance, 18 were identified only by outbreak reports, and 43 were identified only by laboratory surveillance. The outbreak incidence was 1.0 (95% CI, 0.8–1.2) and 0.5 (95% CI, 0.3–0.6) per 1,000 admissions for the 2 different seasons, respectively. To correctly identify NoV outbreaks, the sensitivity and positive predictive value of the clinical surveillance were 68% and 88% and of the laboratory surveillance were 86% and 81%, respectively.CONCLUSIONThe addition of laboratory surveillance significantly improves outbreak surveillance and provides a more complete estimate of NoV outbreaks in hospitals. Laboratory surveillance can be recommended for evaluation of clinical surveillance.Infect Control Hosp Epidemiol 2016;1–7
Three orthogonal ultrasounds fabricate uniform ternary Al-Sn-Cu immiscible alloy
Authors: Zhai W. , Wang B. J. , Liu H. M. , Hu L. , Wei B. 
Published: November 2016

AbstractThe production of Al based monotectic alloys with uniform microstructure is usually difficult due to the large density difference between the two immiscible liquid phases, which limits the application of such alloys. Here, we apply three orthogonal ultrasounds during the liquid phase separation process of ternary Al71.9Sn20.4Cu7.7 immiscible alloy. A uniform microstructure consisting of fine secondary (Sn) phase dispersed on Al-rich matrix is fabricated in the whole alloy sample with a large size of 30 × 30 × 100 mm. The numerical calculation results indicate that the coupled effect of three ultrasounds promotes the sound pressure level and consequently enlarges the cavitation zone within the alloy melt. The strong shockwaves produced by cavitation prevent the (Sn) droplets from coalescence, and keep them suspended in the parent Al-rich liquid phase. This accounts for the formation of homogeneous composite structures. Thus the introduction of three orthogonal ultrasounds is an effective way to suppress the macrosegregation caused by liquid phase separation and produce bulk immiscible alloys with uniform structures.
Downregulation of oncogenic RAS and c-Myc expression in MOLT-4 leukaemia cells by a salicylaldehyde semicarbazone copper(II) complex
Authors: Goh Yan-Yih , Yan Yaw-Kai , Tan Nguan Soon , Goh Su-Ann , Li Shang , Teoh You-Chuan , Lee Peter P. F. 
Published: November 2016

AbstractCopper complexes with potent anti-tumor effect have been extensively developed. Most investigations of their modes of action focused on the biomolecular targets but not the signal transduction between target binding and cell death. We have previously shown that the cytotoxic complex pyridine(2,4-dihydroxybenzaldehyde dibenzyl semicarbazone)copper(II) (complex 1) shows selective binding to human telomeric G-quadruplex DNA over double-stranded DNA in vitro. Herein, we elucidate the mechanism of action by which complex 1 induces apoptosis in MOLT-4 cells. Complex 1 accumulates in the nuclei and differentially downregulates the expression of c-Myc, c-Kit and KRAS oncogenes. Chemical affinity capture assay results show that the complex is associated with c-Myc and KRAS quadruplex sequences in MOLT-4 cells. We further showed that the reduction in Ras protein expression resulted in attenuated MEK-ERK and PI3K-Akt signalling activities, leading to the activation of caspase-dependent apoptosis. Notably, complex 1 increased the sensitivity of MOLT-4 cells to cisplatin and vice versa. Overall, we demonstrated that complex 1 induces apoptosis, at least in part, by suppressing KRAS, c-Kit and c-Myc oncogene expression and the pro-survival MEK-ERK and PI3K-Akt signalling pathways.
Low‐complexity hopping DFT design based on a compact recursive structure
Authors: Juang W.‐H. , Lai S.‐C. , Chen K.‐H. , Tsai W.‐K. , Luo C.‐H. 
Published: November 2016

A novel hopping discrete Fourier transform (DFT) algorithm and its architecture design for efficiently computing time–frequency spectra are presented. Since the sliding process is adopted sample by sample, the spectral bin output data rate is the same as the input data rate. Under the conditions of an M‐sample complex input sequence (M = 256), and N‐point recursive DFT computation (N = 64) for time hop L (L = 4), the proposed method has the following advantages: (i) the computational complexity of Proposed‐I requires only four complex additions and four complex multiplications for each frequency bin, after the first spectral component has been finally calculated; (ii) Proposed‐II utilises a re‐timing scheme to greatly shorten and balance the critical path; (iii) Proposed‐II is less computationally complex than Wang et al.’s method, as the numbers of multiplication and addition operations in the proposed algorithm are 768 and 1024, representing reductions of 50 and 20%, respectively. In addition, the number of coefficients can be reduced by 50% compared with Park et al.’s method. In the FPGA implementation, the proposed design can be operated at 47.26 MHz. It is thus more suitable for use with real‐time analytic applications of time–frequency spectra.
Microstrip switchable filtering power divider with three operating modes
Authors: Zhu Chuanming , Xu Jin , Kang Wei , Wu Wen 
Published: November 2016

A switchable filtering power divider (FPD) with three operating modes is presented, i.e. dual‐band FPD centring at 2.1 and 2.5 GHz, low‐band FPD working at 2.1 GHz, high‐band FPD operating at 2.5 GHz. The bandpass filtering responses are achieved by embedding four dual‐mode resonators. The simulated and measured results are in good agreement.
0.9 V third‐order 132 MHz single‐OPAMP analogue filter in 28 nm CMOS
Authors: De Matteis M. , Donno A. , D'Amico S. , Baschirotto A. 
Published: November 2016

A 28 nm CMOS‐bulk lowpass analogue filter architecture is hereby proposed. The filter is based on an improved Active‐Gm‐RC structure, where both poles of a Miller‐compensated operational amplifier (OPAMP) have been used for synthesising a third‐order filter. Several well‐known issues related to the 28 nm process node have been hereby mitigated by proper circuit/design techniques, enabling large signal‐to‐noise ratio (SNR) and 13.5 dBm IIP3. The proposed circuital solution performs 59 dB‐SNR at 340 µW power consumption from a single 0.9 V supply‐voltage. This allows one of the higher figure‐of‐merit (156 dB) in sub‐1 V analogue filters state of the art.
Ka‐band VCO with parasitic capacitance cancelling technique
Authors: Lee W. , Lee S. , Choi J. , So J. , Kwon Y. 
Published: November 2016

A Ka‐band push–push voltage‐controlled oscillator (VCO) using a parasitic capacitance cancelling technique is presented. To enhance the oscillation frequency (fosc) and the tuning range (TR), the parasitic capacitance of the VCO is cancelled with negative capacitance (NC). To realise NC, a negative impedance circuit (NIC) is analysed and designed. Because of self‐resonance frequency, NC is realised using an open‐circuit stable NIC. For further enhancement of the fosc, the VCO is developed in a push–push operation. The proposed VCO is fabricated in a commercial 0.15 μm GaAs pHEMT process. It shows 12.4% of the TR at 31.6 GHz with 11 dBm output power. With the NIC, the centre frequency of the VCO increases from 20.1 to 31.6 GHz and the TR increases from 5.7 to 12.4% compared with a VCO without the NIC.
Compact wideband circularly polarised dielectric resonator antenna
Authors: Abedian M. , Rahim S.K.A. , Danesh S. , Jamaluddin M.H. , Islam M.T. 
Published: November 2016

A new geometry of compact wideband/dual‐band circularly polarised dielectric resonator antenna (DRA) is presented. First, a wideband DRA is realised by a rectangular dielectric resonator excited by a vertical coaxial probe feed which is supported by a small substrate. Circular polarisation is achieved by utilising a configuration of the DRA feed that excites orthogonal modes inside the DRA. A 3 dB axial‐ratio bandwidth of about 20.8% (9.05–11.14 GHz) is achieved. Second, extension to dual‐band circularly polarised operation is then realised by additionally removing a corner of the rectangular DRA at 45° and adding a floating parasitic strip. The experimental results demonstrate an impedance bandwidth of about 59.8% (6.57–12.18 GHz) and the dual 3 dB axial‐ratio bandwidths of about 10.6% (8.31–9.24 GHz) and 13.5% (10.18–11.66 GHz). The measured peak gain varies from 4.47 to 4.86 dBiC in the lower band and 4.33 to 4.91 dBiC in the upper band.
Manganese dioxide nanoflakes anchored on reduced graphene oxide with superior electrochemical performance for supercapacitors
Authors: Zhang Lifeng , Du Suqing , Liu Yi , Zheng Peng , Yuan Xiaoyan , Huang Jianfeng , Guo Shouwu 
Published: November 2016

Nanostructured manganese dioxide (MnO2)/reduced graphene oxide (RGO) composite is fabricated via a simple hydrothermal process. The MnO2/RGO composite is used to construct supercapacitors as electrodes with high loading mass of active materials. The electrochemical properties of constructed supercapacitors are tested by cyclic voltammetry, galvanostatic charge–discharge and electrochemical impedance spectroscopy. Electrochemical measurements demonstrate that MnO2/RGO electrode exhibits a high specific capacity of 316 F·g−1 at a current density of 200 mA·g−1 and good long‐term cycling stability with capacitance retention of 93% at 500 mA·g−1 after 1000 cycles. The superior electrochemical performance of as‐prepared composite could be mainly attributed to its unique structure, which is composed of MnO2 nanoflakes well‐integrated on the surfaces of RGO.
Surgical Techniques at Cesarean Delivery: A U.S. Survey
Authors: Lyell Deirdre , Power Michael , Murtough Katie , Ness Amen , Anderson Britta , Erickson Kristine , Schulkin Jay 
Published: November 2016

Objective To assess the frequency of surgical techniques at cesarean delivery (CD) among U.S. obstetricians.
Methods Members of the American College of Obstetrician Gynecologists were randomly selected and e-mailed an online survey that assessed surgical closure techniques, demographics, and reasons. Data were analyzed using SPSS (IBM Corp., Armonk, New York, United States), descriptive statistics, and analysis of variance.
Results Our response rate was 53%, and 247 surveys were analyzed. A similar number of respondents either “always or usually” versus “rarely or never” reapproximate the rectus muscles (38.4% versus 43.3%, p = 0.39), and close parietal peritoneum (42.5% versus 46.9%, p = 0.46). The most frequently used techniques were double-layer hysterotomy closure among women planning future children (73.3%) and suturing versus stapling skin (67.6%); the least frequent technique was closure of visceral peritoneum (12.2%). Surgeons who perform double-layer hysterotomy closure had fewer years in practice (15.0 versus 18.7 years, p = 0.021); surgeons who close visceral peritoneum were older (55.5 versus 46.4 years old, p < 0.001) and had more years in practice (23.8 versus 13.8 years practice; p < 0.001).
Conclusion Similar numbers of obstetricians either reapproximate or leave open the rectus muscles and parietal peritoneum at CD, suggesting that wide variation in practice exists. Surgeon demographics and safety concerns play a role in some techniques.
Model for the architecture of caveolae based on a flexible, net-like assembly of Cavin1 and Caveolin discs
Authors: Stoeber Miriam , Schellenberger Pascale , Siebert C. Alistair , Leyrat Cedric , Helenius Ari , Grünewald Kay 
Published: November 2016

Significance
The surface of mammalian cells contains abundant plasma membrane invaginations termed “caveolae.” Caveolae are important for various cellular functions, e.g. signaling, membrane regulation, and vesicular trafficking. Assembly and stability of caveolae depends on a protein coat formed by complexes of cavin and caveolin proteins whose structure has remained elusive. To understand the architecture of caveolae, we structurally analyzed cavin and caveolin complexes and visualized caveolae in cells by electron cryomicroscopy. A regular polyhedron emerged as the most likely architectural principle of caveolae. Polyhedra provide the underlying principle in many biological structures in which spherical curvature is imposed by proteins. We suggest a model for the caveolar coat architecture based on regularly arranged, net-like cavin assemblies and disc-shaped caveolin oligomers.
Effect of O-methylated and glucuronosylated flavonoids from Tamarix gallica on α-glucosidase inhibitory activity: structure–activity relationship and synergistic potential
Authors: Ben Hmidene Asma , Smaoui Abderrazak , Abdelly Chedly , Isoda Hiroko , Shigemori Hideyuki 
Published: November 2016

Abstract
O-Methylated and glucuronosylated flavonoids were isolated from Tamarix gallica as α-glucosidase inhibitors. Structure–activity relationship of these flavonoids suggests that catechol moiety and glucuronic acid at C-3 are factors in the increase in α-glucosidase inhibitory activity. Furthermore, rhamnetin, tamarixetin, rhamnazin, KGlcA, KGlcA-Me, QGlcA, and QGlcA-Me exhibit synergistic potential when applied with a very low concentration of acarbose to α-glucosidase from rat intestine.
New Technique: Acute Minced Expansion Graft of Traumatic Wound Tissue
Authors: Klapper Andrew Mark , Moradian Scott , Pack Philip 
Published: November 2016

ABSTRACT

OBJECTIVES:
Superficial soft tissue injury, such as a skin tear, is common. For such wounds, the authors introduce a novel technique that allows the physician to salvage otherwise discarded tissue as a traumatic graft to highly accelerate wound healing.

METHODS:
A series of 11 patients with superficial soft tissue trauma in which debrided tissues are salvaged back into the wound by means of minced expansion grafting (MEG) are followed from presentation through healing.

RESULTS:
Salvaged tissue replaced back into wounds as MEG grafts greatly accelerated epithelialization and wound closure.

CONCLUSIONS:
Based on their experience with MEG, the authors introduce a new principle for the wound surgeon that no tissue should ever be discarded, but rather salvaged and placed back into the wound.
Nonhealing Wounds Caused by Brown Spider Bites: Application of Hyperbaric Oxygen Therapy
Authors: Hadanny Amir , Fishlev Gregory , Bechor Yair , Meir Oshra , Efrati Shai 
Published: November 2016

ABSTRACT

BACKGROUND:
Bites by Loxosceles spiders (also known as recluse spiders or brown spiders) can cause necrotic ulcerations of various sizes and dimensions. The current standard of care for brown spider bites includes analgesics, ice, compression, elevation, antihistamines, and surgical debridement. Hyperbaric oxygen therapy (HBOT) in the treatment of brown spider bites has been administered in the early stage of ulceration, or 2 to 6 days after the bite. Unfortunately, the diagnosis of spider bite–related ulcers is often delayed and weeks or months may elapse before HBOT is considered.

OBJECTIVE:
To evaluate the effect of HBOT on nonhealing wounds caused by brown spider bites in the late, chronic, nonhealing stage.

METHODS:
Analysis of 3 patients with brown spider-bite healing wounds treated at The Sagol Center for Hyperbaric Medicine and Research in Israel. Patients presented 2 to 3 months after failure of other therapies including topical dressings, antibiotics, and corticosteroids. All patients were treated with daily 2 ATA (atmospheres absolute) with 100% oxygen HBOT sessions.

RESULTS:
All 3 patients were previously healthy without any chronic disease. Their ages were 30, 42, and 73 years. They were treated once daily for 13, 17, and 31 sessions, respectively. The wounds of all 3 patients healed, and there was no need for additional surgical intervention. There were no significant adverse events in any of the patients.

CONCLUSIONS:
Microvascular injury related to brown spider bites may culminate in ischemic nonhealing wounds even in a relatively young, healthy population. Hyperbaric oxygen therapy should be considered as a valuable therapeutic tool even months after the bite.