bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pancreatic β‐Cell production of CXCR3 ligands precedes diabetes onset
Authors: Burke Susan J. , Karlstad Michael D. , Eder Adrianna E. , Regal Kellie M. , Lu Danhong , Burk David H. , Collier J. Jason 
Published: December 2016

AbstractType 1 diabetes mellitus (T1DM) results from immune cell‐mediated reductions in function and mass of the insulin‐producing β‐cells within the pancreatic islets. While the initial trigger(s) that initiates the autoimmune process is unknown, there is a leukocytic infiltration that precedes islet β‐cell death and dysfunction. Herein, we demonstrate that genes encoding the chemokines CXCL9, 10, and 11 are primary response genes in pancreatic β‐cells and are also elevated as part of the inflammatory response in mouse, rat, and human islets. We further established that STAT1 participates in the transcriptional control of these genes in response to the pro‐inflammatory cytokines IL‐1β and IFN‐γ. STAT1 is phosphorylated within five minutes after β‐cell exposure to IFN‐γ, with subsequent occupancy at proximal and distal response elements within the Cxcl9 and Cxcl11 gene promoters. This increase in STAT1 binding is coupled to the rapid appearance of chemokine transcript. Moreover, circulating levels of chemokines that activate CXCR3 are elevated in non‐obese diabetic (NOD) mice, consistent with clinical findings in human diabetes. We also report herein that mice with genetic deletion of CXCR3 (receptor for ligands CXCL9, 10, and 11) exhibit a delay in diabetes development after being injected with multiple low doses of streptozotocin. Therefore, we conclude that production of CXCL9, 10, and 11 from islet β‐cells controls leukocyte migration and activity into pancreatic tissue, which ultimately influences islet β‐cell mass and function. © 2016 BioFactors, 42(6):703–715, 2016
The nephroprotection exerted by curcumin in maleate‐induced renal damage is associated with decreased mitochondrial fission and autophagy
Authors: Molina‐Jijón Eduardo , Aparicio‐Trejo Omar Emiliano , Rodríguez‐Muñoz Rafael , León‐Contreras Juan Carlos , del Carmen Cárdenas‐Aguayo María , Medina‐Campos Omar Noel , Tapia Edilia , Sánchez‐Lozada Laura Gabriela , Hernández‐Pando Rogelio , Reyes José L. , Arreola‐Mendoza Laura , Pedraza‐Chaverri José 
Published: December 2016

AbstractWe have previously reported that the antioxidant curcumin exerts nephroprotection in maleate‐induced renal damage, a model associated with oxidative stress. However, the mechanisms involved in curcumin protective effect were not explored, to assess this issue, curcumin was administered daily by gavage (150 mg/kg) five days before a single maleate (400 mg/kg)‐injection. Curcumin prevented maleate‐induced proteinuria, increased heat shock protein of 72 KDa (Hsp72) expression, and decreased plasma glutathione peroxidase activity. Maleate‐induced oxidative stress by increasing the nicotinamide–adenine dinucleotide phosphate oxidase 4 (NOX4) and mitochondrial complex I‐dependent superoxide anion (O2•—) production, formation of malondialdehyde (MDA)‐ and 3‐nitrotyrosine (3‐NT)‐protein adducts and protein carbonylation and decreased GSH/GSSG ratio. Curcumin treatment ameliorated all the above‐described changes. The maleate‐induced epithelial damage, evaluated by claudin‐2 and occludin expressions, was ameliorated by curcumin. It was found that maleate‐induced oxidative stress promoted mitochondrial fission, evaluated by dynamin‐related protein (Drp) 1 and fission (Fis) 1 expressions and by electron‐microscopy, and autophagy, evaluated by phospho‐threonine 389 from p70 ribosomal protein S6 kinase (p‐Thr 389 p70S6K), beclin 1, microtubule‐associated protein 1A/1B‐light chain 3 phosphatidylethanolamine conjugate (LC3‐II), autophagy‐related gene 5 and 12 (Atg5‐Atg12) complex, p62, and lysosomal‐associated membrane protein (LAMP)‐2 expressions in isolated proximal tubules and by electron‐microscopy and LC‐3 immunolabelling. Curcumin treatment ameliorated these changes. Moreover, curcumin alone induced autophagy in proximal tubules. These data suggest that the nephroprotective effect exerted by curcumin in maleate‐induced renal damage is associated with decreased mitochondrial fission and autophagy. © 2016 BioFactors, 42(6):686–702, 2016
Longitudinal analysis of reporting and quality of systematic reviews in high-impact surgical journals
Authors: Chapman S J , Drake T M , Bolton W S , Barnard J , Bhangu A 
Published: December 2016

Abstract

Background
The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) Statement aims to optimize the reporting of systematic reviews. The performance of the PRISMA Statement in improving the reporting and quality of surgical systematic reviews remains unclear.

Methods
Systematic reviews published in five high-impact surgical journals between 2007 and 2015 were identified from online archives. Manuscripts blinded to journal, publication year and authorship were assessed according to 27 reporting criteria described by the PRISMA Statement and scored using a validated quality appraisal tool (AMSTAR, Assessing the Methodological Quality of Systematic Reviews). Comparisons were made between studies published before (2007–2009) and after (2011–2015) its introduction. The relationship between reporting and study quality was measured using Spearman's rank test.

Results
Of 281 eligible manuscripts, 80 were published before the PRISMA Statement and 201 afterwards. Most manuscripts (208) included a meta-analysis, with the remainder comprising a systematic review only. There was no meaningful change in median compliance with the PRISMA Statement (19 (i.q.r. 16–21) of 27 items before versus 19 (17–22) of 27 after introduction of PRISMA) despite achieving statistical significance (P = 0·042). Better reporting compliance was associated with higher methodological quality (rs = 0·70, P &lt; 0·001).

Conclusion
The PRISMA Statement has had minimal impact on the reporting of surgical systematic reviews. Better compliance was associated with higher-quality methodology.
Reflections on Receiving the ASIS&T 2016 Award of Merit
Authors: Ingwersen Peter 
Published: December 2016

EDITOR'S SUMMARYAt the ASIS&T Annual Meeting in Copenhagen, Peter Ingwersen expressed surprise and gratitude for being honored with the Association's 2016 Award of Merit. The professor emeritus from Denmark's Royal School of Library and Information Science thanked peers for recognizing him as a mentor and research originator. Ingwersen observed that his own areas of research in interactive information retrieval (IR) and scientometrics/webometrics have come together as converging lines of interest, though research and analysis are often restricted by system and feature limitations. Experimentation, Ingwersen stated, is too little focused on the effective workings of IR models and contexts, repeatability and negative research results, and is instead constrained by practicalities and pragmatics. Ingwersen expressed pleasure at the acceptance of web redundancy, citing his theory of polyrepresentation and noting the value of weighting term and search results underlying ranking of web search results. He credited the ASIS&T meetings and publications for developments stemming from original IR experimental studies.
The Modern Records Management Program: An Overview of Electronic Records Management Standards
Authors: Seymour Jennifer 
Published: December 2016

EDITOR'S SUMMARYStandardization is fundamental for bringing a vast variety of electronic records under control. It enables capturing and preserving original records as well as evidence of any access or change to the records. Creating standards within and across organizations is an extreme challenge that must be met. The 2011 Presidential Memorandum on Managing Government Records and subsequent 2012 Directive established values and strategic direction for managing federal electronic records without creating strict standards. The Battelle Record Management Office relies on a Defense Department standard for enterprise content management systems to be secure, searchable and capable of preserving contextual relationships and on the Code of Federal Regulations regarding equivalence of electronic records and signatures to paper. The result demonstrates a record's integrity and authenticity and enables it to be discovered and accessed. Defined access permissions and an audit trail add further assurances. Interoperability through application program interface layers is another requirement, being addressed through advanced platform development, which may provide the solution for authenticity and contextual preservation.
Free‐Surface Turbulent Flow in an Eccentric Stirred Tank
Authors: Yang Fengling , Zhou Shenjie , Zhang Cuixun 
Published: December 2016

AbstractThis work aims at a reliable prediction of the flow dynamics in stirred tanks. The focus is on the free‐surface turbulent flow in an eccentric stirred tank by using the combination of detached‐eddy simulation and volume of fluid model. The flow field, profiles of the free surface, mean velocities, and the macroinstability phenomenon were explored and compared with the available experimental data. A reasonable representation of the free‐surface hydrodynamics was achieved. The findings indicate that the model and simulation strategies presented here can be used with sufficient confidence to predict the free‐surface hydrodynamics in stirred tanks.
Bouquet‐Like NiCo2O4@CoNi2S4 Arrays for High‐Performance Pseudocapacitors
Authors: He Yahui , Xiao Xin , Gao Lin , Li Shaohui , Shen Yan 
Published: December 2016

AbstractThe bouquet‐like NiCo2O4@CoNi2S4 ternary heterostructure on nickel foam is successfully synthesized through a hydrothermal method and electrodeposition. CoNi2S4 nanosheets uniformly cover the surface of nanoneedle‐like NiCo2O4 arrays. The as‐prepared NiCo2O4@CoNi2S4 material was characterized by using scanning electron microscopy (SEM), transmission electron microscopy (TEM), X‐ray photoelectron spectroscopy (XPS), and X‐ray diffraction (XRD). Their electrochemical performance was tested by using cyclic voltammetry (CV) and galvanostatic charge‐discharge (GCD) methods. The bouquet‐like NiCo2O4@CoNi2S4 material with a ternary heterostructure shows the advantages of fast electron and ion transport, a large electroactive surface, and a remarkable areal capacitance (6.25 F cm−2 at current density of 2 mA ⋅ cm−2), which suggests NiCo2O4@CoNi2S4 is a promising material in practical application for pseudocapacitors.
Guest‐Induced Folding and Self‐Assembly of Conformationally Adaptive Macrocycles into Nanosheets and Nanotubes
Authors: Yang Liu‐Pan , Jia Fei , Zhou Qing‐Hai , Pan Fangfang , Sun Jiao‐Nan , Rissanen Kari , Chung Lung Wa , Jiang Wei 
Published: December 2016

AbstractA conformationally adaptive macrocycle is presented, namely zorb[4]arene, which exists in multiple conformations in the uncomplexed state. The binding cavity of zorb[4]arene is concealed, either due to a collapsed conformation or by self‐inclusion. The zorb[4]arene with long alkyl chains manifests itself with surprisingly low melting point and thus exist as an oil at room temperature. Binding of a guest molecule induces the folding and conformational rigidity of zorb[4]arene and leads to well‐defined three‐dimensional structures, which can further self‐assemble into nanosheets or nanotubes upon solvent evaporation, depending on guest molecules and the conformations they can induce.
Isolation of Carboxylic Acids from Biobased Feedstock
Authors: Painer Daniela , Lux Susanne , Grafschafter Annika , Toth Andreas , Siebenhofer Matthäus 
Published: December 2016

AbstractIsolation of low concentrated constituents from side streams of biobased processes has recently received increased technical and economical attention. For energy efficient acid isolation reactive extraction is proposed in literature. The crucial step for efficient process application is the solvent regeneration. Alternatively to conventional reactive extraction, physical extraction with chemical conversion simplifies the technical demand. For continuous operation of heterogeneous catalyzed esterification with physical extraction the Taylor‐Couette disc contactor has proven to be applicable.
Colloidal Alchemy: Conversion of Polystyrene Nanoclusters into Gold
Authors: Chomette Cyril , Tréguer‐Delapierre Mona , Schade Nicholas B. , Manoharan Vinothan N. , Lambert Olivier , Taveau Jean‐Christophe , Ravaine Serge , Duguet Etienne 
Published: December 2016

AbstractIsotropic plasmonic clusters consisting of a controlled number of gold satellites around a silica core are fabricated from silica/polystyrene tetrapod, hexapod, and dodecapod templates. The synthetic pathway includes stages of site‐specific seed adsorption, seed‐mediated growth, and iterative etching/regrowth to reshape the satellites into spheroids. Transmission electron microscopy and electron tomography provide evidence of the symmetry of the clusters. This work paves the way for a comprehensive study of their optical properties.
Testing for linearizability
Authors: Lowe Gavin 
Published: December 2016

SummaryLinearizability is a well established correctness condition for concurrent datatypes. Informally, a concurrent datatype is linearizable if operation calls appear to have an effect, one at a time, in an order that is consistent with a sequential (specification) datatype, with each operation taking effect between the point at which it is called and when it returns. We present a testing framework for linearizabilty. The basic idea is to generate histories of the datatype randomly, and to test whether each is linearizable. We consider five algorithms—one existing, and four new—for testing whether a history of a concurrent datatype implementation is linearizable. Four of these are generic: they will work with any concurrent datatype for which there is a corresponding sequential specification datatype. The fifth considers specifically a history of a concurrent queue. We also combine algorithms in competition parallel in various ways. We perform an experimental evaluation of the different algorithms. We illustrate that the framework is very effective in finding bugs, and discuss the pragmatics of using the framework. Copyright © 2016 John Wiley & Sons, Ltd.
p‐Phosphonated Calix[n]arene Stabilizes Superparamagnetic Nanoparticles for Nitrate and Phosphate Uptake
Authors: D'Alonzo Nicholas J. , Eggers Paul K. , Eroglu Ela , Raston Colin L. 
Published: December 2016

AbstractHighly faceted superparamagnetic magnetite nanoparticles roughly 11 nm in diameter are readily accessible in the presence of p‐phosphonated calix[n]arenes of different ring sizes (n=4, 5 and 6), through the use of a simple co‐precipitation technique. In contrast, the larger calix[8]arene affords spherical particles of comparable size. The maximum magnetization is 70–60 emu g−1, which decreases with increasing size of the calixarene macrocycle, and the evidence indicates that the calixarenes bind to the surface of the nanoparticles via the phosphonate head groups rather than the phenolic oxygen centers. The stabilized nanoparticles show dual functionality: they remove up to 62 % of nitrate nitrogen and 48 % of phosphate from an aqueous effluent after 24 hours at concentrations of only 1 g L−1 of calixarene‐coated nanoparticles.
A Facile and Efficient Method to Fabricate Highly Selective Nanocarbon Catalysts for Oxidative Dehydrogenation
Authors: Zhang Yajie , Wang Jia , Rong Junfeng , Diao Jiangyong , Zhang Jiayun , Shi Chunfeng , Liu Hongyang , Su Dangsheng 
Published: December 2016

AbstractCarbon nanotubes (CNTs) were used in oxidative dehydrogenation (ODH) reactions. Quinone groups on the CNT surface were identified as active sites for the dehydrogenation pathway. Liquid‐phase oxidation with HNO3 is one way to generate various oxygen functionalities on the CNT surface but it produces a large amount of acid waste, limiting its industrial application. Here, a facile and efficient oxidative method to prepare highly selective CNT catalysts for ODH of n‐butane is reported. Magnesium nitrate salts as precursors were used to produce defect‐rich CNTs through solid‐phase oxidation. Skeleton defects induced on the CNT surface resulted in the selective formation of quinone groups active for the selective dehydrogenation. The as‐prepared catalyst exhibited a considerable selectivity (58 %) to C4 olefins, which is superior to that of CNTs oxidized with liquid HNO3. Through the introduction of MgO nanoparticles on the CNT surface, the desorption of alkenes can be accelerated dramatically, thus enhancing the selectivity. This study provides an attractive way to develop new nanocarbon catalysts.
Carbon Dioxide Capture Adsorbents: Chemistry and Methods
Authors: Patel Hasmukh A. , Byun Jeehye , Yavuz Cafer T. 
Published: December 2016

AbstractExcess carbon dioxide (CO2) emissions and their inevitable consequences continue to stimulate hard debate and awareness in both academic and public spaces, despite the widespread lack of understanding on what really is needed to capture and store the unwanted CO2. Of the entire carbon capture and storage (CCS) operation, capture is the most costly process, consisting of nearly 70 % of the price tag. In this tutorial review, CO2 capture science and technology based on adsorbents are described and evaluated in the context of chemistry and methods, after briefly introducing the current status of CO2 emissions. An effective sorbent design is suggested, whereby six checkpoints are expected to be met: cost, capacity, selectivity, stability, recyclability, and fast kinetics.
Can low‐severity fire reverse compositional change in montane forests of the Sierra Nevada, California, USA?
Authors: Becker Kendall M. L. , Lutz James A. 
Published: December 2016

AbstractThroughout the Sierra Nevada, nearly a century of fire suppression has altered the tree species composition, forest structure, and fire regimes that were previously characteristic of montane forests. Species composition is fundamentally important because species differ in their tolerances to fire and environmental stressors, and these differences dictate future forest structure and influence fire regime attributes. In some lower montane stands, shade‐tolerant, fire‐sensitive species have driven a threefold increase in tree density that may intensify the risk of high‐severity fire. In upper montane forests, which were historically characterized by longer fire return intervals, the effects of fire exclusion are both less apparent and less studied. Although land managers have been reintroducing fire to lower and upper montane forests for >4 decades, the potentially restorative effects of these actions on species composition remain largely unassessed. We used tree diameter and species data from 51 recently burned and 46 unburned plots located throughout lower and upper montane forests in Yosemite National Park and Sequoia & Kings Canyon National Parks to examine the effects of low‐ to moderate‐severity (hereafter, lower‐severity) fire on the demography of seven prevalent tree species. The density ofAbies concolor<30 cm diameter at breast height (dbh) was significantly lower in burned plots than unburned plots; densities ofA. concolor30–45 cm dbh,A. magnifica<30 cm dbh, andCalocedrus decurrens<15 cm dbh were lower in burned plots than unburned plots at a marginal level of significance. These diameter thresholds represent the maximum size at which each species is likely to experience significant mortality from lower‐severity fire. We overlaid these thresholds on historical and contemporary diameter distributions to show that: (1) lower‐severity fire has reduced mean tree density to historical levels forA. concolorbut not forC. decurrens, and (2) variability in tree density among plots that burned at lower severity exceeded the range of tree densities reported in historical data sets. High proportions of shade‐tolerant species in some postfire stands may increase the prevalence of shade‐tolerant species in the future, a potential concern for managers who seek to minimize ladder fuels and promote forest structure that is less prone to high‐severity fire.
Limited conifer regeneration following wildfires in dry ponderosa pine forests of the Colorado Front Range
Authors: Rother Monica T. , Veblen Thomas T. 
Published: December 2016

AbstractIn recent years, increased wildfire activity and climate change have raised concern among scientists and land managers regarding current and future vegetation patterns in post‐burn landscapes. We surveyed conifer regeneration 8–15 years after fire in six burn areas in the lower montane zone of the Colorado Front Range. We sampled across a broad range of elevations, aspects, and fire severities and found that densities of ponderosa pine (Pinus ponderosa) and Douglas‐fir (Pseudotsuga menziesii) are generally low, although areas of abundant regeneration do occur. Conifer regeneration was most limited in xeric settings, including more southerly aspects and elevations closer to lower treeline. Additionally, fewer juvenile conifers occurred at greater distances from mature, live trees indicating that seed source as well as topoclimatic setting limits post‐fire tree regeneration. Projecting the extent of future forest cover is uncertain due to the possibility of future pulses of tree establishment and unknown depletion rates of existing seedling populations. However, current patterns of post‐fire seedling establishment suggest that vegetation composition and structure may differ notably from historic patterns and that lower density stands and even non‐forested communities may persist in some areas of these burns long after fire, especially in xeric settings or where no nearby seed source remains.
Biogeochemical drivers of Neotropical ant activity and diversity
Authors: Bujan Jelena , Wright S. Joseph , Kaspari Michael 
Published: December 2016

AbstractHuman activities are rapidly changing biogeochemistry across the globe, yet little is known about biogeochemical impacts on higher‐level consumers. In a Panamanian rainforest, we measured the effects of chronic nitrogen, phosphorus, and potassium fertilization on ants: hyper‐abundant terrestrial arthropods and ecosystem engineers. We tested two compatible hypotheses: the nutrient limitation hypothesis—where adding a limiting nutrient increases ant activity and abundance; and the community homogenization hypothesis—where adding a limiting nutrient decreases ant diversity. Lowland tropical rainforests are expected to be phosphorus‐limited, so we predicted higher ant activity but lower diversity on phosphorus plots. In each fertilization plot, we baited trees and lianas to attract both canopy and ground nesting ants. After controlling for temperature, which accounted for roughly 20% of the variation in ant foraging activity, ant activity remained higher on phosphorus addition plots than on any other fertilization treatment. Genus level diversity was 16% lower on plots receiving phosphorus than the control, consistent with the paradox of enrichment frequently observed in plant communities. This pattern, however, did not hold for species level diversity. The community‐level response was largely driven by the most abundant genus,Azteca, which increased foraging activity and abundance across phosphorus plots. The high activity and low diversity of ants on experimental phosphorus plots point to the potentially strong influence of biogeochemistry on these ubiquitous insects with potential ramifications for the forest food web. This is, to our knowledge, the first study relating biogeochemistry of macronutrients to foraging activity, diversity, and abundance of consumers, implicating strong bottom‐up structuring of the ant community in one of the world's most diverse ecosystems.