bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aspirin Dose and Prevention of Coronary Abnormalities in Kawasaki Disease
Authors: Dallaire Frederic , Fortier-Morissette Zoe , Blais Samuel , Dhanrajani Anita , Basodan Dania , Renaud Claudia , Mathew Mathew , De Souza Astrid M. , Dionne Audrey , Blanchard Joel , Saulnier Harrison , Kaspy Kimberley , Rached-d’Astous Soha , Dahdah Nagib , McCrindle Brian W. , Human Derek G. , Scuccimarri Rosie 
Published: May 2017

BACKGROUND:Acetylsalicylic acid (ASA) is part of the recommended treatment of Kawasaki disease (KD). Controversies remain regarding the optimal dose of ASA to be used. We aimed to evaluate the noninferiority of ASA at an antiplatelet dose in acute KD in preventing coronary artery (CA) abnormalities.METHODS:This is a multicenter, retrospective, nonrandomized cohort study including children 0 to 10 years of age with acute KD between 2004 and 2015 from 5 institutions, of which 2 routinely use low-dose ASA (3–5 mg/kg per day) and 3 use high-dose ASA (80 mg/kg per day). Outcomes were CA abnormalities defined as a CA diameter with a z score ≥2.5. We assessed the risk difference of CA abnormalities according to ASA dose. All subjects received ASA and intravenous immunoglobulin within 10 days of fever onset.RESULTS:There were 1213 subjects included, 848 in the high-dose and 365 in the low-dose ASA group. There was no difference in the risk of CA abnormalities in the low-dose compared with the high-dose ASA group (22.2% vs 20.5%). The risk difference adjusted for potential confounders was 0.3% (95% confidence interval [CI]: −4.5% to 5.0%). The adjusted risk difference for CA abnormalities persisting at the 6-week follow-up was −1.9% (95% CI: −5.3% to 1.5%). The 95% CI of the risk difference of CA abnormalities adjusted for confounders was within the prespecified 5% margin considered to be noninferior.CONCLUSIONS:In conjunction with intravenous immunoglobulin, low-dose ASA in acute KD is not inferior to high-dose ASA for reducing the risk of CA abnormalities.
Diagnóstico dos agroecossistemas da Microbacia Hidrográfica Mariana no Território Portal da Amazônia, Mato Grosso, Brasil
Authors: Roboredo Delmonte , Bergamasco Sonia Maria Pessoa Pereira , Gervázio Wagner 
Published: May 2017

A abertura de novas fronteiras agrícolas na década de 1970, como o caso de Alta Floresta, Mato Grosso, estimulada pelo governo federal, ocorreu sem a preocupação com a preservação das florestas e contribuiu para a geração de fortes externalidades negativas. Este trabalho tem por objetivo realizar o diagnóstico socioambiental da Microbacia Hidrográfica Mariana localizada no município de Alta Floresta, Mato Grosso. A pesquisa foi realizada dentro do enfoque sistêmico por meio de entrevistas semiestruturadas e análises físicas dos solos. Os resultados obtidos identificaram que 78,6% dos entrevistados compraram suas propriedades nos anos 1980/1990, dos quais 84% informaram que não foram orientados para preservação das matas ciliares e 93% dos entrevistados responderam ter interesse em recuperar as áreas degradadas, mas faltam-lhes condições financeiras. O estudo aponta que aquele território está degradado social e ambientalmente em virtude de que 74,5% dos solos dos agroecossistemas pesquisados apresentaram macroporosidade menor que 10%; falta da participação social, além da forte evasão rural que compromete a reprodução social.
A perspectiva da sustentabilidade no campo da saúde
Authors: Agra Filho Severino Soares 
Published: May 2017

A relação da saúde e saneamento tem sido adotada a partir de uma visão preventista restrita. nessa perspectiva os autores questionam, mediante argumentos conceituais, a inadequação dessa visão propugnando a necessidade de uma visão de promoção da saúde bem como a sua aderência com os princípios da sustentabilidade. Dessa forma, o livro torna-se uma contribuição importante para demarcação dos objetivos da sustentabilidade na sua abrangência plena no campo da saúde.

SOUZA, Cezarina Maria Nobre et al. Saneamento: promoção da saúde, qualidade de vida esustentabilidade ambiental. Rio de Janeiro: Fiocruz, 2015. ISBN: 978-85-7541-470-5
effets de la substitution totale du tourteau d’arachide par la fève de coton glandless sur les performances zootechniques de poulets de chair au sénégal
Authors: Diaw M. T. , Dieng A. , Mergeai Guy , Camara A. , Hornick J. L. 
Published: May 2017

Les performances de poulets de chair recevant un aliment dans lequel le tourteau d’arachide a été totalement substitué par la fève de coton glandless (FCG) ont été comparées à celles d’animaux recevant un aliment témoin expérimental (Tém_E), un aliment de commerce (Tém_C) et une ration de formulation très simple composée uniquement de maïs, de FCG, et de concentré minéral et vitaminé. Dès le démarrage, les animaux Tém_C et FCG ont présenté les meilleures croissances. Après 43 jours d’élevage, les différences de poids vifs ont été très importantes entre les lots, essentiellement suite aux différences de consommation alimentaire, de telle sorte que les meilleures vitesses de croissance n’ont pas été nécessairement liées à de meilleurs indices de consommation. De faibles performances pondérales, de faibles ingestions et des mortalités importantes ont été observées avec la ration simplifiée.
Performances de ponte et caractéristiques des oeufs de la pintade locale (<em>Numida meleagris</em>) en système de conduite améliorée dans la région centre du Burkina Faso
Authors: Sanfo R. , Boly Hamidou , Sawadogo L. , Brian O. 
Published: May 2017

Les performances de ponte et les caractéristiques des oeufs de 200 pintades locales (Numida meleagris) couvertes par 100 mâles ont été étudiées au Burkina Faso. L’âge moyen à l’entrée en ponte a été de 5,7 mois avec un poids Burkina Faso. moyen de 931,9 ± 85,3 g. Les deux cycles de ponte étaient situés en saisons sèches, avec des durées de 4,8 mois pour le premier et de 7,5 mois pour le second, avec respectivement les taux de ponte de 21,6 et de 58,7 p. 100, et les performances moyennes de 31,1 et 121,5 oeufs par pintade. Le poids moyen des oeufs a été de 29,2 ± 1,7 g au premier cycle contre 37,8 ± 3,5 g au second. Les dimensions moyennes des oeufs ont été de 47,1 ± 1,9 mm pour la longueur et de 36,5 ± 1,3 mm pour le grand diamètre. L’indice moyen de forme a été plus élevé chez les oeufs du second cycle que chez ceux du premier (0,79 ± 0,05 contre 0,76 ± 0,02). L’équation de régression liant le poids de l’oeuf (Y) à sa longueur (L) et à son grand diamètre (Gd) a été de : Y (g) = -74,22 + 0,91 L (mm) + 1,83 Gd (mm) (R2 = 0,96 ; erreur type = 1,47). Les nuances de coloration des coquilles (rousse = 15,7 p. 100 ; blanche = 19,7 p. 100 ; teintée = 64,6 p. 100) ont été répertoriées pour l’ensemble des oeufs. Le taux de mortalité intracoquille a été de 25,7 p. 100 avec 17,5 p. 100 pour les embryons et 8,2 p. 100 pour les pintadeaux. Des taux de fertilité de 82,7 p. 100 et d’éclosion de 74,3 p. 100 ont été enregistrés.
The Use of patient Reported Outcome Measures for Rheumatoid Arthritis in Japan: A Systematic Literature Review
Authors: Tang Ann Chuo , Kim Hyunchung , Crawford Bruce , Ishii Taeko , Treuer Tamas 
Published: May 2017

Background:
Patient-reported outcomes (PRO) obtained through routine medical care may identify patients’ day-to-day burden and help tackle the disease from the patients’ perspective. However, there is a paucity of information regarding the availability of PRO data and PRO tools for rheumatoid arthritis (RA) in Japan.

Objective:
We reviewed the literature on PRO data availability and to identify PRO measures implemented in Japan for RA patients.

Method:
We conducted a systematic literature review using ICHUSHI and the PubMed databases on PRO measures for RA published from January 2011 to August 2015 in Japan.

Results:
After removing duplicates, 2423 manuscripts were found. From these, 100 manuscripts were included for review and analysis. We found 29 PRO tools that were used to assess various domains of health such as general well-being, pain, functionality, and fatigue. More than 90% of the studies utilized PRO tools for research purpose. Only one study reported PRO tool implementation in the routine medical care.

Conclusion:
The importance of PROs is recognized in Japan. PRO tools varied significantly and were mostly used for research purposes, while reports on the use of PRO measures in routine medical care were limited. Despite the awareness of PROs in the research community, unmet needs remain among RA patients in Japan. Further work is needed to investigate ways in which PROs can better reflect these unmet needs and be utilized in routine medical care.
Klasifikasi Bibit Sapi Peranakan Ongole Menggunakan Metode Pengolahan Citra
Authors: Fatqiyah Leylin , Harjoko Agus 
Published: May 2017

Ongole Crossbreed cattle is the largest cattle in Indonesia. Indonesian consume it’s beef in a large amount. Classification effects beef’s quantity and quality. However, the classification process is measuring manually one by one all this time. Moreover the current standard is too high and inappropriate due to the real exist conditions. Seeing the importance of classification, it is necessary to make a system that is able to classify Ongole Crossbreed cattle stocker.This system will measure quantitative requirement parameters from the image. This system will classify using image processing. Implementation of the system is using Matlab software. This system will classify into four classes, namely class I, class II, class III, and external class III. According to the results, it is obtained that the system is able to measure the body lenght, the chest circumference, and the height with accuracy rates are 90,77%, 93,30% and 93,13%. This system is able to classify the class of Ongole Crossbreed cattle stocker with accuracy rate is 86,67%
Pengendalian Kestabilan Ketinggian pada Penerbangan Quadrotor dengan Metode PID Fuzzy
Authors: Kusuma Panca Agung , Dharmawan Andi 
Published: May 2017

Quadrotor is a kind of unmanned aerial vehicle that have the ability to take of vertically and maintaining its position while flying mid-air. Flying a quadrotor sometimes needs a stable altitude to perform a specific mission. A stable altitude will make easier for pilot to control the movement of the quadrotor to certain direction.This study designed and implemented a system that can stabilises the altitude of a quadrotor by using Fuzzy-PID method. Altitude control system needed to help pilot controls the altitude stability without adjusting the throttle. Control with PID method is a common control system to be implemented on a quadrotor. This control system has a constant that can be tuned with fuzzy logic with linguistic approach to improve the response time when compensating an error. The result of this study shows that Fuzzy PID control method generate a better response time compared with the PID-only method. The implementation of PID control generate an altitude stabilisation with a mean value steady state error of ±1,86 cm, whereas the PID Fuzzy generate a mean value of steady state error of ±1,22 cm.
Pemetaan Potensi Kekeringan Lahan se-pulau Batam menggunakan Teknik Sistem Informasi Geografis (SIG) dan Penginderaan Jauh
Authors: Aprilliyanti Titi , Zainuddin Muhammad 
Published: May 2017

Kekeringan merupakan hubungan antara ketersediaan air yang jauh dibawah kebutuhan baik untuk kebutuhan hidup, pertanian, kegiatan ekonomi dan lingkungan. Informasi mengenai potensi kekeringan sangat diperlukan untuk pencegahan ataupun penanggulangan untuk mengurangi dampak negatif yang ditimbulkan. Adapun tujuan dari penelitian ini adalah menghasilkan peta potensi kekeringan lahan di Batam yang berbasis web. Dalam penelitian ini memanfaatkan teknik penginderaan jauh dan SIG. Penggunaan citra landsat 8 untuk menentukan nilai LST (Land Surface Temperature) dan penggunaan lahan kemudian di overlay dan dilakukan scoring. Tahap akhir penelitian yaitu melakukan validasi terhadap parameter-parameter yang mempengaruhi dengan mengambil beberapa sampel. Adapun hasil akhir dari penelitian ini adalah peta potensi kekeringan se-pulau Batam yang memiliki 5 kelas potensi kekeringan. Kelas potensi kekeringan sangat rendah dengan luas area 2629.45 ha yang dominan terletak pada Kecamatan Sungai Beduk, Sekupang dan Batu Aji. Kelas potensi kekeringan rendah dengan luas area 9585.521 ha yang dominan terletak pada Kecamatan Sekupang. Kelas potensi kekeringan sedang dengan luas area 9507.12 ha yang dominan terletak pada Kecamatan Sekupang. Kelas potensi kekeringan tinggi dengan luas area 7081.392 ha yang dominan terletak pada Kecamatan Sekupang, Sagulung dan Nongsa. Kelas potensi kekeringan sangat tinggi dengan luas area 15600.12 ha yang dominan terletak pada Kecamatan Batam Kota dan Nongsa. Drought is the relationship between the availability of water is far below the need both for the necessities of life, agriculture, economic activities and the environment. Information about potential droughts is indispensable for the prevention or mitigation to reduce the negative impact caused. As for the purpose of this research is to produce a map of potential drought land in the Batam-based web. In this research utilising remote sensing and GIS techniques. The use of landsat 8 to determine the value of the LST (Land Surface Temperature) and land use overlay and then done the scoring. The final stage of research i.e. performs validation against parameters that influence by taking some samples. As for the end result of this research is to map the potential dryness in Island Batam which have 5 classes of potential drought. The class of potential drought is very low with an area of 2629.45 ha, the dominant River is located in Sungai Beduk , Sekupang and Batu Aji. The class of potential low drought with an area of 9,585,521 ha located on the dominant Sub Sekupang. The class of potential drought being with an area of 9507.12 ha located on the dominant Sub Sekupang. The class of potential high dryness with an area of 7,081,392 ha located on the dominant Sub Sekupang, Sagulung and Nongsa. The class of potential drought is extremely high with an area of 15600.12 ha located on the dominant sub Batam city and Nongsa.
FLOATING GASTRORETENTIVE OF AMOXICILLIN USING HARD ALGINATE CAPSULES AND ITS ANTIBACTERIAL ACTIVITIES
Authors: Bangun Hakim 
Published: May 2017

Objective: The aim of this study was to formulate floating gastroretentive of amoxicillin using hard alginate capsules shell and to evaluate antibacterial activities of floating gastroretentive of amoxicillin.Methods: Alginate capsules shell were made by using sodium alginate 80-120 cP. Amoxicillin was prepared in solid dispersion to obtain sustained release requirement for 12 hours. Solid dispersion was prepared by solvent method using polyvinylpyrrolidone (PVP) K30. The solid dispersion was characterized by X-ray diffraction and FTIR analysis. The drug release test was carried out by using USP paddle method in simulated gastric fluid. Concentrations of amoxicillin were determined by using spectrophotometer UV at 272 nm. The antibacterial activity of aliquots dissolution were assessed by using agar plate diffusion method against Staphylococcus aureus and Escherichia coli as bacterial model.Results: The alginate capsules shell were made from sodium alginate 80-120 cP with size 0. The dissolution test results showed that amoxicillin in the form of solid dispersions with weight ratio amoxicillin with PVP K30 was 1:1 provided sustained release of amoxicillin during 12 hours, while the release of amoxicillin without solid dispersion was too slow. The floating lag time was 0 minute and floating time was more than 12 hours. The X-ray diffraction pattern of amoxicillin solid dispersion had amorphous shape. Antibacterial activity test showed that the dissolution aliquots of amoxicillin solid dispersion were effective against Staphylococcus aureus and Escherichia coli.Conclusions: Based on the results of this study, it is concluded that the alginate capsules shell can be used for preparation of floating gastroretentive of amoxicillin using amoxicillin solid dispersion and the dissolution aliqouts give antibacterial effect.Keywords: Floating; gastroretentive; alginate capsule; amoxicillin; solid dispersion; release; antibacterial
ECHO OF LODHRADI KASHAYA IN LIPID PROFILE OF TYPE 2 DIABETES MELLITUS PATIENTS
Authors: Singh Varun Kumar , Reddy Krc 
Published: May 2017

Objective: Lipid profile is matter to concern in fast changing lifestyle, and especially in diabetic mellitus (DM) patients. In arena of DM, obesity and high lipid contour is a causative problem and lead to generate the related problems too. Hence, tracking of lipid profile in DM patients is necessary as part of treatment approach. Hence, the present study was conducted to track the effect of Lodhradi Kashaya spray dried (LKSD) powder on lipid profile in Type 2 DM patients.Methods: Total 31 patients were taken following the guideline mention in Central Council for Research in Ayurveda and Siddha protocol for DM research. They were divided into two groups, Groups A and B and given LKSD (4 and 2 g TDS (three times a day), respectively, dissolved in water) for 3 months. They are investigated for their blood serum creatinine and lipid profile (cholesterol, low-density lipoprotein [LDL], high-density lipoprotein [HDL], very LDL [VLDL], and triglyceride). The patients response has also been noted regarding palatability acceptance and ease of administration. Result: LKSD was found significantly effective in total cholesterol (p=0.001 and 0.073), triglyceride (p=0.002 and 0.003), HDL (p˂0.001 and 0.026), LDL (p=0.563 and p˂0.001), and VLDL (p=0.024 and 0.003). Patients had reported that formulation is easy to take in spite of its astringency in taste.Conclusion: Lodhradi Kashaya has capability to control and take care of disturbance in lipid profile in DM patients and thus enhance their living confidence.Keywords: Ayurveda, Lodhradi Kashaya, Diabetes mellitus, Clinical study, Lipid profile.
COMPARISON AND IDENTIFICATION OF FACTORS INFLUENCING THE FLAVORS OF ENTERAL NUTRITION AGENTS
Authors: Ashizawa Yurika , Ikarashi Nobutomo , Matida Yoshiaki , Watanabe Kazunori 
Published: May 2017

Objective:The flavor of an enteral nutrition formula affects medication adherence as well as patient’s nutritional status and therapeutic efficiency on the major pathology. Therefore, it is important for medical professionals to understand the flavors of enteral nutrition formulas. This study aimed to evaluate the flavors of enteral nutrition formulas and examine the factors influencing these flavors. Methods:A total of 304 students in a pharmaceutical department were subjected to a semantic differential sensory evaluation in which they compared the flavors of digestion and semi-digestion enteral nutrition formulas using a five-point scale. In addition, factors related to good flavor were extracted via factor analyses, and subjected to a covariance structure analysis.Results:In the flavor comparison between digestion and semi-digestion nutrition formulas, semi-digestion nutrition agents scored significantly higher than digestion nutrition formulas did (Welch's t test, P < 0.001, 95% confidence interval [CI] = 0.69–0.99). The factor analyses extracted three subscales of factors related to good flavor: impression of taking, feeling of presence and sense of richness. In a path analysis model to determine the influence of these factor subscales on flavor, impression of taking feeling of presence were found to have significant influences (index of goodness of fit: χ2 = 474.883, df = 62, P < 0.001, GFI = 0.938, AGFI = 0.909, RMSEA = 0.079).Conclusion:Flavor affects medication adherence to enteral nutrition. Therefore, it is important for medical professionals to understand the factors that influence flavor and thus provide patients with better nutrition formulas.
DEVELOPMENT OF PARTICULATE MUCOADHESIVE GEL FOR INTRANASAL DELIVERY
Authors: Gaikwad Dinanath , Kurane Padmini , Mali Dipak , Jadhav Namdeo 
Published: May 2017

Objective: The objective of this research work was to develop mucoadhesive particulates gel of Propranolol HCl for intranasal delivery.Method: Drug loaded mucoadhesive particulates were prepared by spray drying technique using polymers such as HPMC K100 and Carbopol 934P. Batches were prepared according to 32 factorial designs. Result: The mucoadhesive particulates prepared were evaluated for different parameters like drug content, entrapment efficiency, mucoadhesive strength and in vitro drug release. IR, XRD and DSC study revealed that there were no interaction occurs between drug and excipients and confirming reduction in crystallinity. The swelling index and encapsulation efficiency was found to be (0.9266%), (97.44%), angle of repose, Carr’s compressibility index falls in acceptable limits. At the end of 10 hr optimized batch showed 90.23 % drug release and followed zero order release kinetics.Conclusion: Conclusion from result of the studies such as increase in the concentration of polymers contributed in drug release retardation. Although, prepared formulation of nasal administration can be a value addition in treatment for heart diseases like angina pectoris, myocardialKeywords: Mucoadhesive, Particulates, Propranolol hydrochloride, Intranasal.infraction.
EVALUATION OF ANTIBACTERIAL POTENTIAL OF LEAF AND LEAF DERIVED CALLUS EXTRACTS OF ORTHOSIPHON ARISTATUS (BLUME) MIQ.
Authors: Reshi Nissar Ahmad 
Published: May 2017

ABSTRACT: Objective: To evaluate the antibacterial efficacy of chloroform, petroleum ether, ethyl acetate, methanol, ethanol and aqueous extracts of leaf and leaf derived callus of Orthosiphon aristatus against Bacillus cereus, Bacillus subtiltis, Staphylococcus aureus, Streptococcus pyogenes, Enterobater aerogenes, Escherichia coli, Proteus mirabilis, and Klebseilla pneumoniae. Methods: The leaf segments were cut into small pieces of size 1-2 sq. cm and were cultured on Murashige and Skoog solid medium supplemented with different auxins alone and in combination. Antibacterial efficacy was performed by disc diffusion method followed my MIC determination by two fold serial dilution method. Leaf and leaf callus extracts were subjected to the qualitative phytochemical analysis. Results: Maximum callus formation percentage was obtained from the leaf segments cultured on MS medium supplemented with 2, 4-D (2 mg/l). Ethanolic leaf extract showed maximum inhibition activity with 28 mm zone of inhibition against P. mirabilis with MIC value of 0.32 mg/ml. Out of the callus extracts, ethanolic callus extract showed the maximum bio-efficacy against S. aureus with 26 mm zone of inhibition and MIC value of 0.64 mg/ml. Results revealed that both leaf and leaf derived callus are effective against Gram positive and Gram negative test bacteria.Conclusion: The bioefficacy study confirms the strong antibacterial potential of leaf and leaf derived callus of O. aristatus.Keywords: Leaf, Leaf callus, Antibacterial efficacy, Orthosiphon aristatus.