bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attitudes and concerns of doctors and nurses about using a translation application for in-hospital brief interactions with Korean patients
Authors: Day Karen Jean , Song Nicole 
Published: October 2017

Background: New Zealand is becoming more ethnically diverse, with rising numbers of people with limited English language proficiency. Consequently, hospital interactions are increasing where patients have insufficient English to communicate adequately with doctors or nurses for appropriate, effective, and safe care. Translation technology is rapidly evolving, but evidence is limited regarding its usefulness to clinicians.Objective: To examine the acceptability to doctors and nurses of a translation application (app) used on a tablet, in brief interactions with Korean patients.Method: An app was developed to facilitate brief conversations between patients and clinicians as part of clinical care. We used the Technology Acceptance Model 2 to develop semi-structured interview questions for 15 junior and senior doctors and nurses in an urban hospital. Participants used the app to interact with the interviewer as part of a scenario. The interviews were analysed thematically.Results: The app was easy to use, learn to use, and to memorise for future use. It was considered useful for everyday brief interactions, urgent situations where there is no time to call an interpreter, and after hours, to augment the work of interpreters. Subject to perceived usefulness, there appears to be little need for social normalisation of a translation app, other than management support for the costs, maintenance, and implementation of the app for everyday use. Conclusion: Guidelines are required for the use of a translation app by doctors and nurses to augment the interpreter role. A larger study and future research on the patient’s perspective are required.
A problem of coefficient determination in parabolic equations solved as moment problem
Authors: Pintarelli Maria Beatriz 
Published: October 2017

The problem is to find a(t) y w(x; t) such that wt = a(t) (wx)x+r(x; t) under the initial condition w(x; 0) =fi(x) and the boundary conditions w(0; t) = 0 ; wx(0; t) = wx(1; t)+alfa w(1; t) about a region D ={(x; t); 0 <x < 1; t >0}. In addition it must be fulfilled the integral of w (x, t) with respect to x is equal to E(t) where fi(x) , r(x; t) and E(t) are known functions and alfa is an arbitrary real number other than zero.The objective is to solve the problem as an application of the inverse moment problem. We will find an approximated solution and bounds for the error of the estimated solution using the techniques on moments problem. In addition, the method is illustrated with several examples.
GFR estimation based on standardized creatinine and cystatin C: a European multicenter analysis in older adults
Authors: Björk Jonas , Bäck Sten Erik , Ebert Natalie , Evans Marie , Grubb Anders , Hansson Magnus , Jones Ian , Lamb Edmund J. , Martus Peter , Schaeffner Elke , Sjöström Per , Nyman Ulf 
Published: October 2017

Abstract

Background:
Although recommended by the Kidney Disease Improving Global Outcomes, the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPICR) creatinine equation was not targeted to estimate glomerular filtration rate (eGFR) among older adults. The Berlin Initiative Study (BIS1CR) equation was specifically developed in older adults, and the Lund-Malmö revised (LMRCR) and the Full Age Spectrum (FASCR) equations have shown promising results in older adults. Our aim was to validate these four creatinine equations, including addition of cystatin C in a large multicenter cohort of Europeans ≥70 years.

Methods:
A total of 3226 individuals (2638 with cystatin C) underwent GFR measurement (mGFR; median, 44 mL/min/1.73 m2) using plasma iohexol clearance. Bias, precision (interquartile range [IQR]), accuracy (percent of estimates ±30% of mGFR, P30), eGFR accuracy diagrams and probability diagrams to classify mGFR<45 mL/min/1.73 m2 were compared.

Results:
The overall results of BIS1CR/CKD-EPICR/FASCR/LMRCR were as follows: median bias, 1.7/3.6/0.6/−0.7 mL/min/1.73 m2; IQR, 11.6/12.3/11.1/10.5 mL/min/1.73 m2; and P30, 77.5%/76.4%/80.9%/83.5% (significantly higher for LMR, p<0.001). Substandard P30 (<75%) was noted for all equations at mGFR<30 mL/min/1.73 m2, and at body mass index values <20 and ≥35 kg/m2. LMRCR had the most stable performance across mGFR subgroups. Only LMRCR and FASCR had a relatively constant small bias across eGFR levels. Probability diagrams exhibited wide eGFR intervals for all equations where mGFR<45 could not be confidently ruled in or out. Adding cystatin C improved P30 accuracy to 85.7/86.8/85.7/88.7 for BIS2CR+CYS/CKD-EPICR+CYS/FASCR+CYS/MEANLMR+CAPA.

Conclusions:
LMRCR and FASCR seem to be attractive alternatives to CKD-EPICR in estimating GFR by creatinine-based equations in older Europeans. Addition of cystatin C leads to important improvement in estimation performance.
Vox pops in the news: The journalists’ perspective
Authors: Beckers Kathleen 
Published: October 2017

Abstract
Vox pops are a frequent and growing practice in the news. However,
there seems to be a general tendency in journalistic practice to be quite
critical about these interviews with the ordinary (wo)man on the street. Yet,
hardly any research exists about journalists’ evaluation of vox pops or that
has gone further than speculating about why they are used. This study
tackles these research gaps using a survey involving 253 Belgian journalists.
We conclude that vox pops are used mostly by audiovisual journalists, and
that journalists seem to use them mostly because vox pops increase audience
involvement with a news item. Generally, the journalists are quite negative
about vox pops, but journalists who perceive them as involving and good
public opinion tools are more positive. Against our expectations, the experience
of journalists does not influence the evaluation nor the use of vox pops.
A Combinatory Index based Optimal Reallocation of Generators in the presence of SVC using Krill Herd Algorithm
Authors: Kumar Bali Sravana , Suryakalavathi Munugala , Kumar Gundavarapu Venkata Nagesh 
Published: October 2017

AbstractIn the new competitive electric world, it is compulsory for the electrical industry to make effective utilization of the available resources. Optimal tuning of generators and implementation of FACTS devices has been found to be very effective in this regard. In this paper, a combination strategy of optimal tuning of generators using Krill herd (KH) algorithm in the presence of Static VAR Compensator (SVC) has been proposed. A combinatory index (CI), which is a combination of Vi/Vo index and L-index, has been formulated and verified for obtaining the optimal location of SVC. A multi objective function has been formulated for tuning the generators. The results obtained after performing Optimal Power Flow on an IEEE 30 bus system for normal loading and for severe system conditions due to line outage in the presence of SVC using KH has been verified with that of GA, to prove the effectiveness of the chosen methodology.
Estimates of lattice points in the discriminant aspect over abelian extension fields
Authors: Takeda Wataru , Koyama Shin-ya 
Published: October 2017

Abstract
We estimate the number of relatively r-prime lattice points in

K
m

{K^{m}}

with their components having a norm less than x, where K is a number field.
The error terms are estimated in terms of x and the discriminant D of the field K,
as both x and D grow.
The proof uses the bounds of Dedekind zeta functions.
We obtain uniform upper bounds as K runs through number fields
of any degree under assuming the Lindelöf hypothesis.
We also show unconditional results for abelian extensions with a degree less than or equal to 6.
The effect of celery (Apium graveolens L.) on fertility: A systematic review
Authors: Kooti Wesam , Moradi Maryam , Peyro Khadijeh , Sharghi Maedeh , Alamiri Fatima , Azami Milad , Firoozbakht Mohammad , Ghafourian Mehri 
Published: October 2017

Abstract

Background
Fertility and infertility problems are among the complex issues in medicine. The use of herbal products in the treatment of fertility has been considered as an alternative to synthetic drugs. Celery containing known compounds can have an impact on the fertility rate. The aim of this study was to do a systematic review on conducted studies in conjunction with the celery and reproduction.

Methods
Required papers were searched from databases like Science direct, PubMed, Scopus, and Springer. Keywords used in this study were “Apium graveolens L.”, “fertility”, “reproductive system”, “sperm”, “testis”, “delivery”, “sexual hormone”, “LH”, “FSH”, “testosterone”, “semen”, “male”, and “female”. Out of 238 collected articles (published in the period 1995 to 2015), 222 were excluded due to non-relevance and lack of access to the original article.

Results
The notable points were the different results seen by different researchers during different treatment periods or at different doses. Of the 16 studies reviewed in this study, 13 studies have mentioned the positive effect of celery on fertility, while three studies reported the inhibitory effects of this plant.

Conclusions
Celery can have protective effects against substances such as sodium valproate, propylene glycol, and diethyl phthalate causing damages to the testicular structure and spermatogenesis. In this regard, the doses used and the treatment time while using the plant must be accurately investigated. Since there are compounds such as apigenin, the celery can induce inhibitory effects on fertility in case of chronic use or high concentration.
Sirolimus precipitating diabetes mellitus in a patient with congenital hyperinsulinaemic hypoglycaemia due to autosomal dominant ABCC8 mutation
Authors: Dastamani Antonia , Güemes Maria , Walker Joanna , Shah Pratik , Hussain Khalid 
Published: October 2017

AbstractBackground:Sirolimus (mTOR inhibitor) is proven to be effective in children with congenital hyperinsulinism (CHI). Studies in animals suggest that sirolimus may have diabetogenic actions. However, its role in precipitating diabetes mellitus (DM) in children with CHI has not been reported.Case presentation:A 16-year-old female with CHI due to a dominantConclusions:Patients with dominant
Trap type and positioning: how to trap Savi’s pine voles using the tunnel system
Authors: Dell’Agnello Filippo , Mazza Valeria , Martini Matilde , Bertolino Sandro , Capizzi Dario , Riga Francesco , Zaccaroni Marco 
Published: October 2017

AbstractSavi’s pine vole,Microtus savii, is the most widespread Italian vole species, an important rodent pest in agriculture and yet one of the least studied species. One of the reasons for this gap in knowledge is that members of this species are quite difficult to capture with standard trapping procedures, being fossorial and rarely active aboveground. For this reason, we developed a protocol that maximizes trapping success. This method requires the identification of active tunnel holes and the placement of traps directly in front of the exits. We also compared capture and recapture rates of Savi’s pine voles in three different trap types: Institut National de la Recherche Agronomique (INRA), Longworth and Ugglan. If properly equipped with food and nesting material, INRA, Longworth and Ugglan traps showed similar capture rates, but the recapture rate of Ugglan traps was the highest of the three kinds of traps. These results, in combination with the species’ fossorial and social habits, lead us to conclude that Ugglan traps are the best suited for studies on Savi’s pine voles. Our results may have implications for planning and implementing management strategies based on traps rather than rodenticides, as well as field studies on other fossorial small mammals.
On the fourth-order linear recurrence formula related to classical Gauss sums
Authors: Zhuoyu Chen , Wenpeng Zhang 
Published: October 2017

Abstract
Let p be an odd prime with p ≡ 1 mod 4, k be any positive integer, ψ be any fourth-order character mod p. In this paper, we use the analytic method and the properties of character sums mod p to study the computational problem of G(k, p) = τk(ψ)+τk(ψ), and give an interesting fourth-order linear recurrence formula for it, where τ(ψ) denotes the classical Gauss sums.
Motion-based material characterization in sensor-based sorting
Authors: Maier Georg , Pfaff Florian , Becker Florian , Pieper Christoph , Gruna Robin , Noack Benjamin , Kruggel-Emden Harald , Längle Thomas , Hanebeck Uwe D. , Wirtz Siegmar , Scherer Viktor , Beyerer Jürgen 
Published: October 2017

Abstract
Sensor-based sorting provides state-of-the-art solutions for sorting cohesive, granular materials. Typically, involved
sensors, illumination, implementation of data analysis and other components are designed and chosen according to the
sorting task at hand. A common property of conventional systems is the utilization of scanning sensors. However, the
usage of area-scan cameras has recently been proposed. When observing objects at multiple time points, the corresponding
paths can be reconstructed by using multiobject tracking. This in turn allows to accurately estimate the point in time
and position at which any object will reach the separation stage of the optical sorter and hence contributes to decreasing
the error in physical separation. In this paper, it is proposed to further exploit motion information for the purpose of
material characterization. By deriving suitable features from the motion information, we show that high classification
performance is obtained for an exemplary classification task. The approach therefore contributes towards decreasing the
detection error of sorting systems.
Einfluss thermischer und optischer Materialeigenschaften auf die Charakterisierung von Fehlstellen in Faserverbundwerkstoffen mit aktiven Thermografieverfahren
Authors: Maierhofer Christiane , Krankenhagen Rainer , Röllig Mathias , Unnikrishnakurup Sreedhar , Monte Christian , Adibekyan Albert , Gutschwager Berndt , Knazowicka Lenka , Blahut Ales , Gower Mike , Lodeiro Maria , Baker Graham , Aktas Alper 
Published: October 2017

Zusammenfassung
In diesem Beitrag werden zerstörungsfreie Untersuchungen mittels aktiver Thermografie an Probekörpern aus CFK und GFK mit
unterschiedlichen künstlichen Fehlstellen vorgestellt. Dabei wird die zeitliche und örtliche Temperaturverteilung nach der
Erwärmung mit Blitzlampen oder mit einem Infrarot-Strahler mit einer Infrarot-Kamera erfasst. Zur späteren Rekonstruktion
der Messdaten wurde ein numerisches Modell entwickelt. Dazu war die Bestimmung der thermophysikalischen und optischen
Materialeigenschaften erforderlich, was in diesem Beitrag ebenfalls beschrieben wird. Die Ergebnisse der numerischen
Modellierung werden mit den experimentellen Untersuchungen der aktiven Thermografie verglichen. Weiterhin werden die
experimentellen Untersuchungen hinsichtlich der beiden Materialsysteme CFK und GFK und
unter Berücksichtigung der Teiltransparenz des GFK-Materials sowie der unterschiedlichen Anregungsquellen bewertet.
Electrochemical Lignin Degradation in Ionic Liquids on Ternary Mixed Metal Electrodes
Authors: Rauber Daniel , Dier Tobias K.F. , Volmer Dietrich A. , Hempelmann Rolf 
Published: October 2017

Abstract
Lignin is the second most abundant natural polymer and a promissing feedstock for the generation of renewable aromatic chemicals. We present an fundamental approach for the electrocatalytic cleavage of lignin dissolved in a recoverable, inexpensive ionic liquid using mixed metal oxide electrodes of different compositions. The distribution of depolymerization products generated by electrochemical oxidation were analyzed by means of mass spectrometry. The distribution and yield of the cracked species was found to depended strongly on the implemented metal catalyst and therefore offers the potential to tailor the amount and composition of the low molecular weight cleavage products. This approach could help to provide a more sustainable valorization of lignin for the potential production of high value aromatic compounds due to synergistic effects.
Novel Design, Preparation, Characterization and Antimicrobial Activity of Silver Nanoparticles during Oak Acorns Bark Retrograde
Authors: Mesgarzadeh Iraj , Reza Akbarzadeh Ali , Rahimi Rahmatollah , Maleki Ali 
Published: October 2017

Abstract
In search for a probable local solution for Qarasu River problems and based on our prescience about metal ion chelating/reducing ability of tannins which are found in large amount in oak acorns bark, Quercus brantii (Persian oak) acorns bark extract was exploited as reducing/capping agent in silver nanoparticles synthesis. Synthesis was carried out as a single-step method at room temperature, and without consuming any external energy by using these renewable barks. The crystallinity, size and shape of the nanoparticles were characterized by X-ray diffraction and scanning electron microscopy (SEM) respectively. The involvement of phenolic compounds in metal ion reduction was supported by UV-Visible and infrared spectroscopies and by acidity and conductivity measurements. The SEM-based particle size distribution analysis and antimicrobial susceptibility test of oak acorns bark-extract-mediated silver nanoparticles against bacterial effluent were pointed out to the critical proportion of silver salt to the capping/reducing agent. It seems that the bactericidal action depends on the extent to which accumulation of silver nanoparticle (Ag-Np) in bacterial cell surface alters the silver nanoparticle colloidal stability in broth medium.
Postinjury Induction of Activated ErbB2 Selectively Hyperactivates Denervated Schwann Cells and Promotes Robust Dorsal Root Axon Regeneration
Authors: Han Seung Baek , Kim Hyukmin , Lee Hyunkyoung , Grove Matthew , Smith George M. , Son Young-Jin 
Published: October 2017

Following nerve injury, denervated Schwann cells (SCs) convert to repair SCs, which enable regeneration of peripheral axons. However, the repair capacity of SCs and the regenerative capacity of peripheral axons are limited. In the present studies we examined a potential therapeutic strategy to enhance the repair capacity of SCs, and tested its efficacy in enhancing regeneration of dorsal root (DR) axons, whose regenerative capacity is particularly weak. We used male and female mice of a doxycycline-inducible transgenic line to induce expression of constitutively active ErbB2 (caErbB2) selectively in SCs after DR crush or transection. Two weeks after injury, injured DRs of induced animals contained far more SCs and SC processes. These SCs had not redifferentiated and continued to proliferate. Injured DRs of induced animals also contained far more axons that regrew along SC processes past the transection or crush site. Remarkably, SCs and axons in uninjured DRs remained quiescent, indicating that caErbB2 enhanced regeneration of injured DRs, without aberrantly activating SCs and axons in intact nerves. We also found that intraspinally expressed glial cell line-derived neurotrophic factor (GDNF), but not the removal of chondroitin sulfate proteoglycans, greatly enhanced the intraspinal migration of caErbB2-expressing SCs, enabling robust penetration of DR axons into the spinal cord. These findings indicate that SC-selective, post-injury activation of ErbB2 provides a novel strategy to powerfully enhance the repair capacity of SCs and axon regeneration, without substantial off-target damage. They also highlight that promoting directed migration of caErbB2-expressing SCs by GDNF might be useful to enable axon regrowth in a non-permissive environment.SIGNIFICANCE STATEMENTRepair of injured peripheral nerves remains a critical clinical problem. We currently lack a therapy that potently enhances axon regeneration in patients with traumatic nerve injury. It is extremely challenging to substantially increase the regenerative capacity of damaged nerves without deleterious off-target effects. It was therefore of great interest to discover that caErbB2 markedly enhances regeneration of damaged dorsal roots, while evoking little change in intact roots. To our knowledge, these findings are the first demonstration that repair capacity of denervated SCs can be efficaciously enhanced without altering innervated SCs. Our study also demonstrates that oncogenic ErbB2 signaling can be activated in SCs but not impede transdifferentiation of denervated SCs to regeneration-promoting repair SCs.
Sitagliptin 100 mg vs glimepiride 1–3 mg as an add-on to insulin and metformin in type 2 diabetes (SWIM)
Authors: Kesavadev Jothydev , Pillai Pradeep Babu Sadasivan , Shankar Arun , Krishnan Gopika , Jothydev Sunitha 
Published: October 2017

Objective
To compare the effect of sitagliptin (100 mg) vs glimepiride (1–3 mg) as add-on therapy in Indian type 2 diabetes (T2DM) patients on treatment with insulin and metformin (SWIM study).

Research design and methods
This 24-week, controlled, open-label study randomized T2DM patients (n = 440) receiving a stable dose of metformin and insulin combination therapy to sitagliptin (100 mg) or glimepiride (1–3 mg) as add-on therapy. Baseline HbA1c was ≥7.3% and ≤8.5%. After a 6-week titration period for glimepiride (dose titrated every 2 weeks by 1 mg up to a maximum of 3 mg daily), patients were continued for 18 weeks on their respective tolerable doses of glimepiride (ranging from 1 mg to 3 mg) or sitagliptin (100 mg) along with metformin and insulin.

Results
Greater reductions in HbA1c and TDD of insulin were achieved with sitagliptin compared to glimepiride. HbA1c targets and reductions in TDD were achieved by more patients on sitagliptin than on glimepiride. Reductions in both body weight and BMI were also noted among patients on sitagliptin when compared to those on glimepiride, and more hypoglycemic events occurred with glimepiride treatment than with sitagliptin.

Conclusions
Sitagliptin (100 mg), when compared to glimepiride (1–3 mg), bestowed beneficial effects to T2DM patients in terms of achieving greater glycemic control and also brought significant reductions in total daily dose of insulin required, bodyweight, BMI and hypoglycemic events. Overall, the results suggest that sitagliptin (100 mg) is a superior agent over glimepiride (1–3 mg) as an add-on to insulin–metformin therapy among Asian Indians with T2DM.
Selective blood sampling for FGF-23 in tumor-induced osteomalacia
Authors: Schober Hans-Christof , Kneitz Christian , Fieber Franziska , Hesse Kathrin , Schroeder Henry 
Published: October 2017

Summary
Tumor-induced osteomalacia (TIO) is caused by the hormone fibroblast growth factor 23 (FGF-23). It is mainly produced in the tissue of mesenchymal tumors. Patients with TIO frequently suffer from a chronic decompensated pain syndrome and/or muscle weakness with postural deformity. Despite the severity of the disease, the diagnosis is frequently established late. In some cases, it takes several years to establish the condition. This case report concerning a 68-year old woman demonstrates the selective blood sampling for FGF-23 as path-breaking diagnostics to confirm the diagnosis of a neuroendocrine tumor.

Learning points:

Tumor-induced osteomalacia is a rare condition compared to other paraneoplastic syndromes.

It causes complex symptoms such as progressive reduction of physical capacity, exhaustion, fatigue, a decompensated pain syndrome of the musculoskeletal system and fractures of several bones.

Elevated serum levels of FGF-23 implicate massive phosphate elimination and resulting hypophosphatemia.

The diagnosis is often established over a period of several years because the localization of small FGF-23-producing tumors is complicated.

It is the combination of MRI and selective blood sampling for FGF-23 which permits reliable identification of tumors causing TIO and leads to accurate localization.

In a patient with generalized pain and reduced physical capacity, osteological parameters such as phosphate, 25-OH vitamin D3 and 1,25-(OH)2D3, as well as bone-specific alkaline phosphatase levels in serum should be determined. Hypophosphatemia should always lead to further diagnostic investigations aiming at the detection of an FGF-23-producing tumor.