bluuebunny/crossref_metadata_2025_split huggingface dataset:
The analytic decision‐making preference model to evaluate the disaster readiness in emergency departments: The A.D.T. model
Authors: Ortiz‐Barrios Miguel Angel , Aleman‐Romero Brandon Antonio , Rebolledo‐Rudas Janeth , Maldonado‐Mestre Heberth , Montes‐Villa Lizeth , De Felice Fabio , Petrillo Antonella 
Published: November 2017

AbstractIn recent years, a series of important emergencies have been taken place worldwide in industrial plants. After the occurrence of a disaster, it is essential to activate the correct emergency procedures. Particularly, it is important to direct people injured in hospitals which are able to handle emergencies. Thus, nowadays, the emergency services require a management process starting from the disaster moment to the involvement of all actors participating in the process to provide integral, safe, and quality attention. The aim of this study is to help hospitals become better prepared for major disasters and public health emergencies and to evaluate the readiness of emergency departments for a disaster situation. A hybrid model called the “analytic decision‐making preference model” based on analytic hierarchy process, decision‐making trial and evaluation laboratory, and technique for order of preference by similarity to ideal solution methods is proposed. Analytic hierarchy process is used to determine the criteria and subcriteria weights. Then, decision‐making trial and evaluation laboratory is used to evaluate interdependence between criteria and subcriteria. After this, technique for order of preference by similarity to ideal solution is applied to rank the emergency departments from highest to lowest according to their closeness coefficient. A real‐life application in Colombia is presented.
Validation of an all‐sky imager–based nowcasting system for industrial PV plants
Authors: Kuhn Pascal , Nouri Bijan , Wilbert Stefan , Prahl Christoph , Kozonek Nora , Schmidt Thomas , Yasser Zeyad , Ramirez Lourdes , Zarzalejo Luis , Meyer Angela , Vuilleumier Laurent , Heinemann Detlev , Blanc Philippe , Pitz‐Paal Robert 
Published: November 2017

AbstractBecause of the cloud‐induced variability of the solar resource, the growing contributions of photovoltaic plants to the overall power generation challenges the stability of electricity grids. To avoid blackouts, administrations started to define maximum negative ramp rates. Storages can be used to reduce the occurring ramps. Their required capacity, durability, and costs can be optimized by nowcasting systems. Nowcasting systems use the input of upward‐facing cameras to predict future irradiances. Previously, many nowcasting systems were developed and validated. However, these validations did not consider aggregation effects, which are present in industrial‐sized power plants. In this paper, we present the validation of nowcasted global horizontal irradiance (GHI) and direct normal irradiance maps derived from an example system consisting of 4 all‐sky cameras (“WobaS‐4cam”). The WobaS‐4cam system is operational at 2 solar energy research centers and at a commercial 50‐MW solar power plant. Besides its validation on 30 days, the working principle is briefly explained. The forecasting deviations are investigated with a focus on temporal and spatial aggregation effects. The validation found that spatial and temporal aggregations significantly improve forecast accuracies: Spatial aggregation reduces the relative root mean square error (GHI) from 30.9% (considering field sizes of 25 m2) to 23.5% (considering a field size of 4 km2) on a day with variable conditions for 1 minute averages and a lead time of 15 minutes. Over 30 days of validation, a relative root mean square error (GHI) of 20.4% for the next 15 minutes is observed at pixel basis (25 m2). Although the deviations of nowcasting systems strongly depend on the validation period and the specific weather conditions, the WobaS‐4cam system is considered to be at least state of the art.
System approach to pedagogical discourse: CLD learners
Authors: Rojas Eliana D. , Avitia Maria J. 
Published: November 2017

AbstractThis paper examines the achievement gap for culturally and linguistically diverse (CLD) learners through the lens of Bronfenbrenner's bioecological theory of human development. The population of CLD students in the United States continues to grow. Across the nation, CLD students continue to struggle in an increasingly accountability‐based education system. In this paper, we will situate the variables known to contribute to CLD students’ achievement at the national, local, and individual levels within Bronfenbrenner's model. We will also provide some pedagogical recommendations that everyone working with CLD students should know and do.
Body image dissatisfaction in patients undergoing breast reconstruction: Examining the roles of breast symmetry and appearance investment
Authors: Teo Irene , Reece Gregory P. , Huang Sheng‐Cheng , Mahajan Kanika , Andon Johnny , Khanal Pujjal , Sun Clement , Nicklaus Krista , Merchant Fatima , Markey Mia K. , Fingeret Michelle Cororve 
Published: November 2017

AbstractObjectiveReconstruction as part of treatment for breast cancer is aimed at mitigating body image concerns after mastectomy. Although algorithms have been developed to objectively assess breast reconstruction outcomes, associations between objectively quantified breast aesthetic appearance and patient‐reported body image outcomes have not been examined. Further, the role of appearance investment in explaining a patient's body image is not well understood. We investigated the extent to which objectively quantified breast symmetry and patient‐reported appearance investment were associated with body image dissatisfaction in patients undergoing cancer‐related breast reconstruction.MethodsBreast cancer patients in different stages of reconstruction (n = 190) completed self‐report measures of appearance investment and body image dissatisfaction. Vertical extent and horizontal extent symmetry values, which are indicators of breast symmetry, were calculated from clinical photographs. Associations among breast symmetry, appearance investment, body image dissatisfaction, and patient clinical factors were examined. Multi‐variable regression was used to evaluate the extent to which symmetry and appearance investment were associated with body image dissatisfaction.ResultsVertical extent symmetry, but not horizontal extent symmetry, was associated with body image dissatisfaction. Decreased vertical extent symmetry (β = −.19, P < .05) and increased appearance investment (β = .45, P < .001) were significantly associated with greater body image dissatisfaction while controlling for clinical factors.ConclusionsBreast symmetry and patient appearance investment both significantly contribute to an understanding of patient‐reported body image satisfaction during breast reconstruction treatment.
Lung function after extremely preterm birth—A population‐based cohort study (EXPRESS)
Authors: Thunqvist Per , Tufvesson Ellen , Bjermer Leif , Winberg Anna , Fellman Vineta , Domellöf Magnus , Melén Erik , Norman Mikael , Hallberg Jenny 
Published: November 2017

AbstractBackground and objectivesFollow‐up studies of children and young adults born very‐to‐moderately preterm show persistent and significant lung function deficits. The aim of the study was to determine lung function and airway mechanics in school‐aged children born in 2004 to 2007 and extremely preterm (after 22‐26 weeks of gestation).MethodsIn a population‐based cohort of children born extremely preterm and controls born at term (n = 350), follow‐up at 6½‐years‐of‐age was performed using spirometry and impulse oscillometry. Associations to gestational age, smallness for gestational age (SGA), and bronchopulmonary dysplasia (BPD) were assessed.ResultsChildren born extremely preterm had lower forced vital capacity (FVC, z‐score: −0.7, 95%CI: −1.0;−0.4), forced expiratory volume (FEV1, z‐score: −1.1, 95%CI: −1.4; −0.8), higher frequency‐dependence of resistance (R5‐20, 0.09, 95%CI: 0.05; 0.12 kPa · L−1 · s−1) and larger area under the reactance curve (AX, 0.78, 95%CI: 0.49; 1.07 kPa · L−1) than controls. In children born at 22‐24 weeks of gestation, 24% had FVC and 44% had FEV1 below the lower limit of normal. SGA and severe BPD only marginally contributed to pulmonary outcomes. Asthma‐like disease was reported in 40% of extremely preterm children and 15% of controls.ConclusionMany children born extremely preterm have altered airway mechanics and significant obstructive reduction in lung function. This warrants consideration for treatment and continued follow‐up.
Elevated difenacoum metabolism is involved in the difenacoum‐resistant phenotype observed in Berkshire rats homozygous for the L120Q mutation in the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene
Authors: Boitet Maylis , Hammed Abdessalem , Chatron Nolan , Debaux Jean Valéry , Benoit Etienne , Lattard Virginie 
Published: November 2017

AbstractBACKGROUNDSoon after difenacoum began to be used, resistance to this rodenticide was detected in rats in northeast Hampshire and northwest Berkshire in England. Resistance to difenacoum has been reported to be stronger in rats from Berkshire than in rats from Hampshire. Surprisingly, after the discovery of the vitamin K epoxide reductase complex subunit 1 (Vkorc1) gene, rats from Berkshire and Hampshire were all shown to be homozygous for the L120Q mutation in Vkorc1.RESULTSThis study aimed to evaluate the resistance of Berkshire rats to confirm their extreme resistance and determine mechanisms supporting this resistance. For this purpose, we created a quasicongenic rat F7 strain by using a Berkshire rat as a donor to introduce the L120Q mutation in Vkorc1 into the genetic background of an anticoagulant‐susceptible recipient strain. The use of F7 rats enabled demonstration of (i) the level of resistance to difenacoum conferred by the L120Q mutation, (ii) co‐dominance of the L120 and Q120 alleles, (iii) the extreme resistance of Berkshire rats compared with Q120/Q120 rats as a consequence of additional resistance mechanisms, and (iv) the involvement of cytochrome P 450 (CYP450) enzymes in this extreme resistance.CONCLUSIONThis study demonstrated that elevated CYP450 oxidative metabolism leading to accelerated difenacoum detoxification is involved in the Berkshire phenotype. © 2017 Society of Chemical Industry
A case study in identifying targeted patients population in major depressive disorder by enhanced enrichment design
Authors: Zhang Peter , Carroll Kevin , Hobart Mary , Augustine Carole , Koch Gary 
Published: November 2017

Despite advances in clinical trial design, failure rates near 80% in phase 2 and 50% in phase 3 have recently been reported. The challenges to successful drug development are particularly acute in central nervous system trials such as for pain, schizophrenia, mania, and depression because high‐placebo response rates lessen assay sensitivity, diminish estimated treatment effect sizes, and thereby decrease statistical power. This paper addresses the importance of rigorous patient selection in major depressive disorder trials through an enhanced enrichment paradigm. This approach led to a redefinition of an ongoing, blinded phase 3 trial algorithm for patient inclusion (1) to eliminate further randomization of transient placebo responders and (2) to exclude previously randomized transient responders from the primary analysis of the double blind phase of the trial. It is illustrated for a case study for the comparison between brexpiprazole + antidepressant therapy and placebo + antidepressant therapy. Analysis of the primary endpoint showed that efficacy of brexpiprazole versus placebo could not be established statistically if the original algorithm for identification of placebo responders was used, but the enhanced enrichment approach did statistically demonstrate efficacy. Additionally, the enhanced enrichment approach identified a target population with a clinically meaningful treatment effect. Through its successful identification of a target population, the innovative enhanced enrichment approach enabled the demonstration of a positive treatment effect in a very challenging area of depression research.
Robust node‐to‐node consensus of linear multiagent systems with directed switching topologies subject to uncertain pinning communications
Authors: Wang Peijun , Yu Wenwu , Yu Xinghuo 
Published: November 2017

SummaryThis paper is focused on the node‐to‐node consensus problem of multiagent systems consisting of general linear node dynamics under directed switching topologies. Specifically, it is assumed that the multiagent systems under consideration have 2 layers, ie, leader layer and follower layer. When uncertainties on the pinning links between the 2 layers exist, the coordination goal is to present some robust control laws, which are distributed such that the states of each follower asymptotically converge to those of its corresponding leader. By using tools from M‐matrix theory and multiple Lyapunov methods, some sufficient criteria are derived to achieve this goal. Finally, 2 simulation examples are performed to validate the effectiveness of the theoretical results.
Influence of Phosphidation on CoSe2 Catalyst for Hydrogen Evolution Reaction
Authors: Bose Ranjith , Kim Tae‐Hyun , Koh Beomsoo , Jung Chi‐Young , Yi Sung Chul 
Published: November 2017

AbstractThe development of highly active and earth‐abundant electrocatalyst for the hydrogen evolution reaction (HER) is essential for hydrogen based energy technologies. Recently, cobalt chalcogenides and phosphides have been extensively investigated as a promising class of non‐precious electrocatalyst for HER because of its high catalytic activity. Here, we have grown a novel and efficient cobalt selenide|cobalt phosphide (CoSe2|CoP) based HER catalyst on carbon fiber paper (CFP) through a facile conversion of CoSe2 nanostructures into a hybrid CoSe2|CoP by phosphidation. Phosphorus compositions in the CoSe2|CoP nanosheets are controllable by adjusting the time duration of phosphidation viz., 15, 30 and 60 min. The catalyst CoSe2|CoP/CFP in acidic media at 30 min showed higher catalytic activity with low overpotential (η) of 140 mV at 10 mA/cm2 and a Tafel slope of 42 mV/dec than parent CoSe2/CFP (η ‐ 219 mV at 10 mA/cm2; Tafel slope ‐ 44 mV/dec) and CoP/CFP (η ‐ 168 mV at 10 mA/cm2; Tafel slope ‐ 86 mV/dec). The improved HER activity of CoSe2|CoP is attributed to the formation of the hybrid nanosheets and the synergistic effect between CoP and CoSe2. Moreover, the surface morphology of CoSe2|CoP at 30 min catalyst plays a significant role in electron transportation. Thus, the present work opens a new potential way to design and develop novel hybrid HER electrocatalysts based on CoSe2|CoP as an efficient energy conversion system through their composition and structural morphology.
3D Printing of Flexible Electronic Devices
Authors: Yang Hui , Leow Wan Ru , Chen Xiaodong 
Published: November 2017

AbstractCompared to traditional , simple, planar or tubular flexible devices fabricated by spin‐coating, casting, or extrusion, 3D‐printed flexible electronic devices possess complicated geometries with precisely prescribed microarchitectures and excellent mechanical properties for satisfying all kinds of individual requirements. However, the full utilization of 3D‐printing technology to realize 3D‐printed flexible electronic devices remains limited by the flexibility and conductivity of 3D‐printing materials. To achieve 3D‐printed flexible electronic devices, the flexibility of 3D‐printed flexible devices and functionalization of conductive materials or hard silicon‐based electronic devices are combined. These 3D‐printed flexible electronic devices can be applied widely in the fields of personal wearable devices, prosthetic organs for the disabled, and human–computer interfaces. To further promote the rapid advent of 3D‐printed flexible electronic devices, the recent strategies and future developmental directions of fabricating these complex electronic devices are discussed here.
Introduction to the Handbook of Life Course Health Development
Authors: Halfon Neal , Forrest Christopher B. , Lerner Richard M. , Faustman Elaine M. , Tullis Ericka , Son John 
Published: November 2017

AbstractA critical mass of research linking early life events, experiences, and exposures with adult health conditions is delineating the developmental origins of many common chronic diseases. This emerging body of life course health development (LCHD) research specifies the complex adaptive processes by which both adversity and opportunity are integrated into developing biobehavioral systems. It is also challenging long-held views about origins and etiology of health and disease. There is a growing momentum among practitioners and policymakers to “connect the dots” between this rapidly expanding evidence base and the related practices and policies that are implemented within the fields of medicine, public health, nursing, mental health, education, urban planning, community development, social welfare, and others. At the same time, there is a strong impetus among LCHD researchers to continue to fill the substantial gaps in our knowledge and to ensure that research findings are appropriately synthesized and translated before being applied in clinical, public health, or public policy contexts. Comprised of 26 chapters that grew out of the 2013 Maternal and Child Health (MCH) Life Course Research Agenda-Setting Meeting that was organized by the MCH Life Course Research Network (LCRN) and funded by Health Resources and Services Administration-Maternal and Child Health Bureau (HRSA-MCHB), this volume assesses what has been learned as the LCHD field has emerged, takes stock of what we know and do not know about how health and disease develop, provides some initial guidance regarding the kinds of interventions and efforts that can be beneficial, and lays the foundation for a research agenda that identifies high-priority areas for basic, clinical, population, and translational investigations in order to strategically target resources and efforts and advance the life course health sciences. In this introductory chapter, we begin by providing a rationale for the publication of this volume, including an historical overview that traces the emergence of the LCHD field and provides evidence of a significant, but as yet incomplete, transformation in how we think about and promote health. We go on to describe the purpose, structure, and content of the volume and examine some of the challenges the evolving field must consider as it adaptively moves forward. Finally, we provide readers with information about each section and chapter in this volume, including the impressive backgrounds of the various experts who contributed substantial amounts of both time and original thinking in their roles as authors.
Pediatric Type 2 Diabetes: Prevention and Treatment Through a Life Course Health Development Framework
Authors: Salsberry Pamela , Tanda Rika , Anderson Sarah E. , Kamboj Manmohan K. 
Published: November 2017

AbstractEstimates project that one in three US adults may have diabetes in 2050. Until very recently, type 2 diabetes mellitus (T2DM) was a disease diagnosed in adults, but as the childhood obesity epidemic has spread, the diagnosis of T2DM in adolescents has become more common. Early indicators suggest that the disease may be more severe and more difficult to manage when diagnosed in adolescents. It is projected that adolescents with T2DM will lose approximately 15 years of life. The economic burden of T2DM rises significantly as the years with disease increase. This grim forecast highlights that not only will the disease burden be significant but the economic burden will be high. The risk for developing T2DM begins in utero. Individual health development trajectories build from this starting point, the result of multiple factors that accumulate across time and are the result of biological conditioning during sensitive developmental periods. A major aim of this chapter is to demonstrate that a life course health development approach to pediatric T2DM is critical to a sound national strategy to prevent and treat pediatric T2DM. We review major factors known to influence the development of pediatric T2DM and track these across childhood. While these factors will likely change over the next decade, what will not change is the importance of placing these factors into context and recognizing that T2DM development is highly sensitive to the timing and social structures of multiple environmental exposures. Research recommendations are discussed through a life course lens.
A Life Course Approach to Hearing Health
Authors: Russ Shirley A. , Tremblay Kelly , Halfon Neal , Davis Adrian 
Published: November 2017

AbstractChallenges to hearing health are a significant public health problem. At least ten million Americans have a hearing loss that interferes with the understanding of normal speech. If lesser degrees of loss are included, the number rises to 28 million. Although there have been considerable advances in understanding the etiology of hearing loss, with genetic causes now thought to account for up to 50% of congenital losses, in many individual cases, the cause of hearing loss remains unknown. This lack of knowledge of the basic pathophysiology of hearing difficulties hampers prevention and treatment efforts. Growing interest in life course theory has led to suggestions that it could prove useful to apply a life course lens to the study of hearing loss, and of hearing health, throughout the life span. In this paper we consider the implications of the Life Course Health Development model for understanding the mechanisms, pathways, and determinants of hearing ability. We consider the implications of early hearing loss for health development over the life course and the factors through the life course that contribute to hearing ability in adult life. We consider the concept not just of hearing loss but of “hearing health” and how to achieve it, the research priorities that are suggested by this review, and the implications for policy and practice.
Using the Fragile Families and Child Wellbeing Study (FFCWS) in Life Course Health Development Research
Authors: Geller Amanda , Jaeger Kate , Pace Garrett 
Published: November 2017

AbstractThe Fragile Families and Child Wellbeing Study (FFCWS) is a nationally representative birth cohort study of approximately 4900 children born in large US cities between 1998 and 2000. Nonmarital childbearing increased dramatically in the second half of the twentieth century, raising questions about the capabilities of unmarried parents, the nature of parental relationships, and their implications for child health development and wellbeing. The FFCWS has become a leading source of information about unmarried parents and their children and about child health development more generally. The study contains biological and social indicators of children’s cognitive health development as well as social determinants of health and children’s broader social environment. This rich measurement, coupled with a longitudinal design and multilevel structure, makes it an ideal resource for life course health development research. This chapter describes the demographic, scholarly, and policy context in which the FFCWS was designed, as well as technical details that will enable new users to use the study effectively. We include details of sampling, data availability, variable structure and content, as well as features of the data that enable it to be used in longitudinal research. Finally, the chapter provides information about resources that will be available in the future and institutional resources available for users of the data.