bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for cardiovascular death in urgent-start peritoneal dialysis patients: a multicenter retrospective cohort study
Authors: Meng Lingfei , Yang Liming , Zhu Xueyan , Sun Zhanshan , Zhang Xiaoxuan , Cui Wenpeng 
Published: October 2024

Abstract

Background: Urgent-start peritoneal dialysis (USPD) has been identified as the efficient approach to initiate renal replacement treatment in end-stage renal disease patients. Cardiovascular mortality of urgent dialysis is an important issue. The present work focused on assessing risk factors related to cardiovascular death in USPD patients.
Methods: We carried out the present multicenter retrospective cohort study in Northeast China, included adults initiating USPD between 2013 to 2019. Follow-up was conducted in every patient till the occurrence events below: technical failure, death, loss-to-follow-up, and renal transplantation.
Results: There were altogether 1549 cases enrolled into this work. Among them, 123 encountered cardiovascular death. Upon multivariate regression, predictors of cardiovascular death included advanced age (HR 1.045, 95%CI [1.031, 1.060]; p < 0.001), higher eGFR (HR 1.084, 95%CI [1.052, 1.117]; p = 0.001), combined with diabetes (HR 1.471, 95%CI [1.026, 2.110]; p = 0.036), and advanced heart failure stages (class III versus class 0-I, HR 5.262; 95%CI [3.281, 8.437]; p < 0.001; class IV versus class 0-I, HR 6.409; 95%CI [4.145, 9.912]; p < 0.001). In addition, the predictors of cardiovascular death in diabetic USPD patients included advanced age (HR 1.050, 95%CI [1.024, 1.076]; p < 0.001), low serum creatinine (HR 0.999, 95%CI [0.998, 1.000]; p = 0.036) and advanced heart failure stage (class III versus class 0-I, HR 8.814; 95%CI [4.709, 16.501]; p< 0.001; class IV versus class 0-I, HR 5.334; 95%CI [2.904, 9.796]; p < 0.001). Moreover, the predictors of cardiovascular death in elderly USPD patients were advancedheart failure stage (class III versus class 0-I, HR 4.081; 95%CI [2.323, 7.170]; p < 0.001; class IV versus class 0-I, HR 5.178; 95%CI [3.066, 8.746]; p < 0.001).
Conclusions: Risk factors related to cardiovascular death included advanced age, higher eGFR, combined with diabetes, and advanced heart failure stages among USPD patients.
The Importance of Adult Self-education and Cultural Awareness When Creating a Sustainable Organizational Culture
Authors: Supranavičienė Ugnė , Gedvilienė Genutė , Stancikas Egidijus , Karasevičiūtė Salomėja 
Published: October 2024

Abstract

Relevance.Culture and education are undoubtedly two of the major factors that determine both the level of societal development and an individual’s full-fledged social life in contemporary society. Cultural awareness and adult self-education serve to produce various forms of activities; they help accumulate and transform diverse culture forms and create essentially new potential for anyone whose aim is to transition to a higher level of organizational culture. The growth of organizational culture also depends on the quality of cultural awareness and adult self-education, whereas the perspective of an individual’s life in general is determined by opportunities created for the individual to participate in an organization’s system.
Methodology. The results were quantified with further developed qualitative research methods. The research was performed in compliance with the following main principles of ethics: beneficence and ethical and honestly expressed opinions. The research was based on the methodological dispositions of transformative learning and experiential learning theory. Research was conducted in the following three stages: 1) research into generic competences (GC), identifying the importance of self-education of cultural awareness and how this relates to other competences; 2) research into the openness of adults to cultural awareness and self-education; and 3) hosting of a focus group discussion to identify prerequisites for the creation of a sustainable organizational culture.
This paper presents the conditions needed for an employee to self-educate and acquire cultural awareness competency and how it relates to building a sustainable organizational culture. Can organizations achieve this?
The aim of this paper is to reveal the importance of adult education and cultural awareness when creating a sustainable organizational culture.
The Impact of Organizational Culture on Career Leaving Among Nurses: Examining Global Nurses’ Shortage Through the Lenses of Organizational Culture: A Systematic Review
Authors: Kiptulon Evans Kasmai , Elmadani Mohammed , Szőllősi Anna , Galgalo Dahabo Adi , Wami Girma Alemu , Siket Adrienn Ujváriné ,   Maté Orsolya1
Published: October 2024

Abstract

Background: Globally, healthcare settings are facing significant nursing staff shortages occasioned by nurse turnover and experiencing difficulties in recruitment and retention of nursing professionals. The pressure of shortage of nurses and other healthcare workforce is so severe that World Health Organization has warned European countries and the globe that this shortage is a “ticking timebomb” if an action is not taken. Organizational culture is an important antecedent of nurse turnover that remains weakly studied. Despite a plethora of research on the global shortage of nurses and turnover, there have been few dedicated systematic literature reviews, and this study aimed to fill this gap.
Objective: To collect and collate evidence available in the literature on the impact of organizational culture on career and professional leaving among nurses and emphasize the critical role of organizational culture in turnover and retention of nurses.
Methods: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, a comprehensive literature search according to the Population, Exposure and Outcome search strategy model was performed in six major electronic databases, including PubMed, Ovid Medline, Embase, CINAHL, Scopus and Web of Science, in July 2023. Studies that met the inclusion criteria set were screened using Rayyan and Covidence. Mixed Methods Appraisal Tool was used to assess the quality and risk of bias of the included articles.
RESULTS: The search yielded a total of 2,396 articles, of which 30 were included. The results demonstrate that nurse turnover remains a complex issue and continues to plague nations of the world. Organizational culture is an important antecedent of nurse turnover, with different types of organizational culture affecting turnover differently. We found overall that, negative organizational culture and climate was consistently associated with nurse’s turnover while positive culture improved nurse retention.
Conclusion: This study confirmed that organizational culture seriously influences nurse turnover. Nurse managers and hospital managements should strive to continuously monitor and build positive organizational cultures to raise quality of service delivery and retain nurse workforce.
The Joint Influence of Farm Production Diversity and Food Market Visits on Smallholder Household Diets in Northern Ethiopia
Authors: Balcha Tsegay , Lahiff Edward , Donnellan Trevor , Chisholm Nick 
Published: October 2024

Abstract

Although various studies have examined the relative influence of farm production diversity and market access on household dietary diversity, few studies have empirically investigated their joint interplay in shaping such diversity. This research addresses this gap based on cross-sectional data from 396 smallholder households in rural Tigray in Northern Ethiopia. In the analysis, a graphical interpretation of the relationship between farm production diversity and market access is followed by a deeper investigation using Poisson estimation methods. We use an alternative measure of market access, households’ frequency of food market visits, rigorously tested for stability, and compare it with alternative measures. Our findings reveal that farm production diversity and market access, jointly and independently, have a positive and significant nonlinear influence on rural smallholder household dietary diversity. The right mix between farm production diversity and smallholder households’ frequency of food market visits increases rural household dietary diversity.
Domaining based on geological information, variogram analysis and clustering algorithms
Authors: Khorram Farzaneh , Morshedy Amin Hossein 
Published: October 2024

Abstract

Domaining plays a significant role when major statistical or geostatistical variations are observed across a site, which can influence the results of spatial modeling. In this paper, hard and fuzzy clustering algorithms are used as a tool for domaining, with the input containing a combination of geological layers (lithology, alteration, and mineral zone), geochemical layers (Cu, Mo, Ag, and Au grade), and coordinates of boreholes from two exploration campaigns in eastern Kahang deposit, central Iran. The algorithms include the K-means, hierarchical, affinity propagation, self-organizing map (SOM), fuzzy c-means, and Gustafson-Kessel. The optimal number of clusters was determined between 3 and 4. The fuzziness and weighting parameters were respectively obtained in the ranges of 1.1-1.3 and 0.1-0.3, by considering and comparing several hard and fuzzy cluster validity indices.
Directional variograms were then calculated to define the anisotropy ellipsoid for the data within each domain to detect the model with the highest degree of anisotropic discrimination among domains. Based on the Jensen-Shannon measure, this model was found to be SOM, using a combination of qualitative and quantitative data as input information, and providing three domains as an output.
FACTORES ASSOCIADOS AO ABANDONO ESCOLAR DA RAPARIGA NO 3º CICLO DO ENSINO BÁSICO NA ESCOLA PRIMÁRIA COMPLETA 25 DE JUNHO, DISTRITO DE NHAMATANDA 2021-2022
Authors: Domingos Armando , Magande Edson Evaristo 
Published: October 2024

RESUMO
O presente artigo visa analisar os factores associados à disortográfica como dificuldade especifica de aprendizagem nos alunos de 3º ciclo de Ensino Básico na Escola Primária Completa 25 de Junho. Para efectivação deste objetivo, utilizamos as seguintes metodologias: a pesquisa mista (qualitativa e quantitativa) método bibliográfico, com recursos as técnicas, a observação directa, entrevista e questionário. No que tange a população e amostra de estudo, tivemos como população 960 alunos e 14 professores, nesse âmbito a amostra foi escolhida aleatoriamente 100 alunos (50 rapazes e 50 raparigas) de idade compreendida de 12-14 anos e 10 professores da Escola Primária Completa 25 de Junho. O problema em questão nesta temática é a dificuldade de escrita, onde confundem os fonemas, discordância de número, de gênero, pontuação deslocada, junção de palavras e letras e no outro momento omissão de algumas letras nas palavras. Relativamente aos principais resultados de pesquisa, constatamos no 3º ciclo de Ensino Básico na Escola Primária Completa 25 de Junho, os factores do tipo percetivo, intelectual, linguístico, afetivo-emocional, e factores de tipo pedagógico. Para efeito, há necessidade de promoção de capacitações aos professores em matéria de cognição e linguagem, metodologias de ensino diferenciadas para melhorar as suas práticas.

Palavras-Chave: Aprendizagem. Disortografia. Factores. Dificuldade.
Synthesis Techniques and Biomedical Applications of Cyclodextrin Metal-Organic Frameworks
Authors: Kankva Divyesh , Prajapati Parixit , Elossaily Gehan M. , Prajapati Bhupendra 
Published: October 2024

Abstract:
Cyclodextrin Metal-Organic Frameworks (CD MOFs) represent an innovative
class of materials with remarkable properties and a broad range of applications.
This review provides a comprehensive overview of the synthesis techniques, structural
characterization, and diverse applications of CD-MOFs. By combining cyclodextrins
(CDs) with metal-organic frameworks (MOFs), CD-MOFs are developed with enhanced
functionality. The synthesis methods, including various metal sources, coordination
modes, and post-synthesis modifications, are discussed alongside advanced structural
characterization techniques like X-ray crystallography and spectroscopic methods. The
unique characteristics of CD-MOFs, such as high specific surface area, tunable porosity,
and customizable chemical structure, make them exceptional candidates for applications
in gas adsorption, drug delivery, catalysis, sensing, and environmental remediation.
Notably, CD-MOFs show significant promise as nanocarriers in drug delivery systems,
offering improved therapeutic outcomes due to their efficient encapsulation and controlled
release capabilities. The review highlights recent advancements and underscores
the potential impact of CD-MOFs in driving future innovations across various scientific
fields.
Efficacy and Safety of Sarpogrelate on Symptom Improvement in Patients with Peripheral Arterial Disease (PAD) and/or Being at Risk of PAD: A Single Arm, Multi-Centered, Open-Label Trial
Authors: Won Jong Chul , Song Tae-Jin , Park Jae Hyoung , Kim Hee-Tae , Lee Kyong Hoon , Park Keun Yong , Jeong Ho-Seung , Jeon Ung , Min Kyung Wan , Lim Soo 
Published: October 2024

Aims:
To assess the efficacy and safety of sarpogrelate (300 mg) for symptom improvement
in patients having peripheral arterial disease (PAD) and/or being at risk of PAD in clinical
practice using the Peripheral Artery Questionnaire (PAQ).

Background:
Symptomatic changes with antiplatelets in patients with PAD are limited.

Objective:
To determine the effect and safety of sarpogrelate on the PAQ at 24 weeks from baseline.

Methods:
A total of 1003 patients having PAD and/or being at risk of PAD from 17 tertiary hospitals
in South Korea who were treated with sarpogrelate, were enrolled in this study. PAQs were
collected at baseline and at 12 and 24 weeks, together with physical examination and vital signs
measurements. Lifestyle pattern was also investigated.

Results:
The average PAQ Summary Score in the efficacy evaluation analysis group significantly
improved from 62.9 ± 23.7 at baseline to 68.9 ± 21.7 at 24 weeks (P<0.0001). Physical limitation
items significantly improved from 69.5 ± 30.0 at baseline to 72.9 ± 28.3 after 24 weeks
(P=0.0011). Symptom stability also significantly improved from 52.1 ± 21.6 at baseline to 63.6 ±
22.9 after 24 weeks (P<0.0001). Symptoms, treatment satisfaction, quality of life, and social limitation
domains all improved after treatment. A total of 201 patients reported adverse events
(20.0%), not directly associated with treatment.

Conclusion:
Treatment with 300 mg (orally) of sarpogrelate demonstrated statistically significant
improvements in all domains and for the summary score of the PAQ at 24 weeks, it gave good results
in terms of safety. Sarpogrelate may be helpful in reducing symptoms related to PAD.
Factors Associated with Axial Spondyloarthritis Remission in a Cohort of Saudi Patients with Longstanding Disease: A Multicenter Prospective
Cohort Study
Authors: Almansouri Abdulrahman Y , Alsindi Eman , Almani Ibraheem , Basalama Mohmed , Attar Suzan , Abdulaziz Sultana 
Published: October 2024

Background/Aim:
Earlier treatment in axial spondyloarthritis (axSpA) was proposed to
alter disease prognosis in this often-challenging condition. We aimed to assess the proportion of
patients and prognostic factors associated with axSpA remission.

Objective:
The aim was to determine the number of patients with Ankylosing Spondylitis Disease
Activity Score with C-reactive protein (ASDAS-CRP) of <2.1 (inactive/moderate disease activity).
We also evaluated global functioning and health using the Assessment of Spondyloarthritis International
Society-Health Index (ASAS-HI).

Patients and Methods:
Patients with axSpA who were receiving targeted synthetic/biological disease-
modifying anti-rheumatic drug (ts/bDMARDs) treatments and visited the rheumatology units
at two tertiary-care centers between December 2021 and December 2022 were prospectively interviewed.
Data regarding patient demographics, disease features, active and previous ts/bDMARDs
treatments, and disease activity scores were obtained. Patients were assessed using the ASDAS-
CRP, ASDAS-erythrocyte sedimentation rate (ASDAS-ESR), Bath Ankylosing Spondylitis
Disease Activity Index (BASDAI), and ASAS-HI.

Results:
Overall, 60 patients with axSpA were included in this study (women, n = 35); 25 (41.7%)
and 36 (62.1%) achieved an ASDAS-CRP of <2.1 and an ASAS-HI of ≤5 (good health), respectively.
Out of the 60 patients, 75% (n = 45) were treated with anti-tumor necrosis factor. Factors
associated with achieving the target ASDAS-CRP included age (p = 0.019), sex (p = 0.015), employment
status (p = 0.015), education level (p = 0.030), and the number of previous ts/bDMARDs
treatments (p = 0.019). Additionally, the ASDAS-CRP strongly correlated with spinal
pain and moderately correlated with the ASAS-HI, BASDAI, and the number of previous ts/bDMARDs
treatments.

Conclusions:
Remission was observed in 41.7% of patients, indicating a challenge in achieving
target disease activity. However, 62.1% attained good health. Achieving remission was associated
with younger age, male sex, a higher level of education, lower level of spinal pain, better global
function by ASAS-HI, employment, and receiving their first ts/bDMARDs treatment. Our findings
may potentially improve disease prognosis with the earlier use of ts/bDMARDs in those without
favorable features by implementing an early axSpA intervention strategy.
A Low Transformed Tubal Rank Tensor Model Using a Spatial-Tubal Constraint for Sample Clustering with Cancer Multi-omics Data
Authors: Zhang Sheng-Nan , Gao Ying-Lian , Zhang Yu-Lin , Shang Junliang , Zheng Chun-Hou , Liu Jin-Xing 
Published: October 2024

Background:
Since each dimension of a tensor can store different types of genomics data,
compared to matrix methods, utilizing tensor structure can provide a deeper understanding of
multi-dimensional data while also facilitating the discovery of more useful information related to
cancer. However, in reality, there are issues such as insufficient utilization of prior knowledge in
multi-omics data and limitations in the recovery of low-tubal-rank tensors. Therefore, the method
proposed in this article was developed.

Objective:
In this paper, we proposed a low transformed tubal rank tensor model (LTTRT) using a
spatial-tubal constraint to accurately partition different types of cancer samples and provide reliable
theoretical support for the identification, diagnosis, and treatment of cancer.

Method:
In the LTTRT method, the transformed tensor nuclear norm based on the transformed tensor
singular value decomposition is characterized by the low-rank tensor, which can explore the
global low-rank property of the tensor, resolving the challenge of the tensor nuclear norm-based
method not achieving the lowest tubal rank. Additionally, the introduction of weighted total variation
regularization is conducive to extracting more information from sequencing data in both spatial
and tubal dimensions, exploring cross-correlation features of multiple genomic data, and addressing
the problem of overlooking prior knowledge from various perspectives. In addition, the L1-norm is
used to improve sparsity. A symmetric Gauss‒Seidel-based alternating direction method of multipliers
(sGS-ADMM) is used to update the LTTRT model iteratively.

Results:
The experiments of sample clustering on multiple integrated cancer multi-omics datasets
show that the proposed LTTRT method is better than existing methods. Experimental results validate
the effectiveness of LTTRT in accurately partitioning different types of cancer samples.

result:
The experiments of sample clustering on multiple integrated cancer multi-omics datasets show that the proposed LTTRT method is better than existing methods. Experimental results validate the effectiveness of LTTRT in accurately partitioning different types of cancer samples.

Conclusion:
The LTTRT method achieves precise segmentation of different types of cancer samples.
Leveraging Network Insights into Positive Emotions and Resilience for Better Life Satisfaction
Authors: Kyriazos Theodoros , Poga Mary 
Published: October 2024

Introduction/Objective
Within a network analysis framework, this study explored the relationships between positive emotions, resilience, and life satisfaction. Positive emotions and resilience are critical to enhancing psychological well-being, but their complex interplay requires further investigation, particularly in a Greek adult population.

Methods
We conducted a cross-sectional study with 1,230 Greek adults (67.6% females, 32.4% males), using a network analysis to assess the relationships among positive emotions, resilience, and life satisfaction. Data were collected through the Scale of Positive and Negative Experience (SPANE-8), the Brief Resilience Scale (BRS), and the Satisfaction with Life Scale (SWLS). Network structures were constructed using the graphical LASSO technique for partial correlation analysis, and Bayesian networks were applied to generate Directed Acyclic Graphs (DAGs) to identify directional pathways. Centrality metrics were used to determine critical variables in the network.

Results
Happiness, pleasure, and contentment are examples of positive emotions that are central nodes in the network that are highly correlated with higher levels of life satisfaction. Resilience, primarily as a recovery mechanism from stress, showed weaker direct associations with life satisfaction. The DAG revealed that positive emotions significantly influenced life satisfaction, suggesting their pivotal role in improving well-being.

Conclusion
The findings underscore the importance of positive emotions in enhancing life satisfaction, suggesting that interventions targeting emotional well-being may be more effective than those focused solely on resilience. These insights offer a foundation for developing psychological interventions to improve life satisfaction.