bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of threonine deficiency on intestinal integrity and immune response to feed withdrawal combined with coccidial vaccine challenge in broiler chicks
Authors: Zhang Qian , Chen Xi , Eicher Susan D. , Ajuwon Kolapo M. , Applegate Todd J. 
Published: December 2016

AbstractFor this study, threonine (Thr) deficiency was hypothesised to exacerbate the intestinal damage induced by feed withdrawal with coccidial infection because of its high obligatory requirement by the gut; two dietary Thr treatments (0·49 and 0·90 %) were applied to chicks from 0 to 21 d of age. At 13 d of age, feed was withdrawn for 24 h from one-half of birds of each dietary treatment with subsequent gavage of a 25× dose of coccidial vaccine. Overall, there were four treatments with eight replicate cages per treatment. Under combined challenge, birds fed the Thr-deficient diet had 38 % lower 13–21-d body weight gain (P≤0·05) compared with birds fed the Thr-control diet. At 21 d, the challenged group fed low Thr had higher number of oocysts (+40 %,P=0·03) and lower crypt depth (−31 %,P<0·01). In addition, birds fed the low-Thr diet had higher gut permeability as measured after 2 h of administration of fluorescein isothiocyanate-dextran (3–5 kDa,P<0·01), which may be attributed to decreased IgA production (P=0·03) in the ileum. In caecal tonsils, the challenged group fed low Thr had lower CD3:Bu-1 ratio (P≤0·05), along with a tendency for lower CCR9 mRNA expression in birds fed the low-Thr diet (P=0·10). In addition, Thr deficiency tended to increase IL-10 mRNA expression regardless of infection (P=0·06), but did not change interferon-γmRNA expression upon coccidial infection (P>0·05). Overall, Thr deficiency worsened the detrimental effects of combined feed withdrawal and coccidial infection on growth performance and oocyst shedding by impairing intestinal morphology, barrier function, lymphocyte profiles and their cytokine expressions.
Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk
Authors: Bergeron Nathalie , Williams Paul T. , Lamendella Regina , Faghihnia Nastaran , Grube Alyssa , Li Xinmin , Wang Zeneng , Knight Rob , Jansson Janet K. , Hazen Stanley L. , Krauss Ronald M. 
Published: December 2016

AbstractProduction of trimethylamine-N-oxide (TMAO), a biomarker of CVD risk, is dependent on intestinal microbiota, but little is known of dietary conditions promoting changes in gut microbial communities. Resistant starches (RS) alter the human microbiota. We sought to determine whether diets varying in RS and carbohydrate (CHO) content affect plasma TMAO levels. We also assessed postprandial glucose and insulin responses and plasma lipid changes to diets high and low in RS. In a cross-over trial, fifty-two men and women consumed a 2-week baseline diet (41 percentage of energy (%E) CHO, 40 % fat, 19 % protein), followed by 2-week high- and low-RS diets separated by 2-week washouts. RS diets were assigned at random within the context of higher (51–53 %E)v. lower CHO (39–40 %E) intake. Measurements were obtained in the fasting state and, for glucose and insulin, during a meal test matching the composition of the assigned diet. With lower CHO intake, plasma TMAO, carnitine, betaine andγ-butyrobetaine concentrations were higher after the high-v. low-RS diet (P<0·01 each). These metabolites were not differentially affected by highv. low RS when CHO intake was high. Although the high-RS meal reduced postprandial insulin and glucose responses when CHO intake was low (P<0·01 each), RS did not affect fasting lipids, lipoproteins, glucose or insulin irrespective of dietary CHO content. In conclusion, a lower-CHO diet high in RS was associated with higher plasma TMAO levels. These findings, together with the absence of change in fasting lipids, suggest that short-term high-RS diets do not improve markers of cardiometabolic health.
The successional pathway of the tree community and how it shapes the fruit-feeding butterfly community in an Afrotropical forest
Authors: Valtonen Anu , Malinga Geoffrey M. , Nyafwono Margaret , Nyeko Philip , Owiny Arthur , Roininen Heikki 
Published: December 2016

Abstract:The relative importance of different bottom-up-mediated effects in shaping insect communities in tropical secondary forests are poorly understood. Here, we explore the roles of vegetation structure, forest age, local topography (valley vs. hill top) and soil variables in predicting fruit-feeding butterfly and tree community composition, and tree community composition in predicting fruit-feeding butterfly community composition, in different-aged naturally regenerating and primary forests of Kibale National Park, Uganda. We also examine which variables are best predictors of fruit-feeding butterfly species richness or diversity. Butterflies (88 species) were sampled with a banana-baited trap and trees (98 taxa) with a 40 × 20-m sampling plot at 80 sampling sites. The environmental variables explained 31% of the variation in the tree community composition, the best predictors being local topography, forest age and cover of Acanthus pubescens (a shrub possibly arresting succession). The fruit-feeding butterfly community composition was better predicted by tree community composition (explaining 10% of the variation) rather than vegetation structure, local topography or soil factors. Environmental variables and tree species richness (or diversity) were poor predictors of butterfly species richness (or diversity). Our results emphasize the importance of tree community to recovery of herbivorous insect communities in tropical secondary forests.
Mechanisms responsible for the hypocholesterolaemic effect of regular consumption of probiotics
Authors: Reis S. A. , Conceição L. L. , Rosa D. D. , Siqueira N. P. , Peluzio M. C. G. 
Published: December 2016

AbstractCVD affect a large proportion of the world’s population, with dyslipidaemia as the major risk factor. The regular consumption of both probiotic bacteria and yeast has been associated with improvement in the serum lipid profile. Thus, the present review aims to describe and discuss the potential mechanisms responsible for the hypocholesterolaemic effect of regular consumption of probiotic bacteria and yeast. Regarding the hypocholesterolaemic effect of probiotic bacteria, the potential mechanisms responsible include: deconjugation of bile salts; modulation of lipid metabolism; and decreased absorption of intestinal cholesterol through co-precipitation of intestinal cholesterol with the deconjugated bile salts, incorporation and assimilation of cholesterol in the cell membrane of the probiotics, intestinal conversion of cholesterol in coprostanol, and inhibition of the expression of the intestinal cholesterol transporter Niemann–Pick C1 like 1 (NPC1L1) in the enterocytes. The potential mechanisms responsible for the hypocholesterolaemic effect of probiotic yeasts include: deconjugation of bile salts; co-precipitation of intestinal cholesterol with the deconjugated bile salts; incorporation and assimilation of cholesterol in the cell membrane; and inhibition of hepatic cholesterol synthesis. The regular consumption of probiotic bacteria and yeast, as a non-pharmaceutical approach to help manage cardiovascular risk, holds promise, according to the beneficial hypocholesterolaemic effects described herein. However, the hypocholesterolaemic effects vary according to the strains used, the physiological state of the host, and the type of diet to which the probiotics are added. Further studies are necessary to fill the gaps with regard to the knowledge related to this topic.
Risk and protective factors for comorbid internalizing and externalizing problems among economically disadvantaged African American youth
Authors: Liu Jingwen , Mustanski Brian , Dick Danielle , Bolland John , Kertes Darlene A. 
Published: December 2016

Abstract
Comorbidity of internalizing and externalizing problems and its risk and protective factors have not been well incorporated into developmental research, especially among racial minority youth from high-poverty neighborhoods. The present study identified a latent comorbid factor as well as specific factors underlying internalizing and externalizing problems among 592 African American adolescents living in economically disadvantaged neighborhoods (291 male; M age = 15.9 years, SD = 1.43 years). Stressful life events and racial discrimination were associated with higher comorbid problems, whereas stressful life events and exposure to violence were associated with higher specific externalizing problems. Collective efficacy was associated with both lower specific externalizing problems and lower comorbid problems. Moreover, high collective efficacy buffered the risk effects of stressful life events and racial discrimination on comorbid problems. Our results demonstrated the advantages of latent variable modeling to understanding comorbidity by articulating impacts of risk factors on comorbid and specific components underlying internalizing and externalizing problems. They also highlighted the protective effect of collective efficacy in mitigating risks for these problems. Broadly, these findings call for more studies on comorbidities in developmental psychopathology among youth from diverse sociocultural backgrounds.
The role of parental marital discord in the etiology of externalizing problems during childhood and adolescence
Authors: Jarnecke Amber M. , South Susan C. , Elkins Irene J. , Krueger Robert F. , Tully Erin C. , Iacono William G. 
Published: December 2016

AbstractPrevious research has established that parental marital discord is associated with higher levels of offspring externalizing behaviors, but it is unclear how parental relationship functioning is associated with the genetic and environmental variance on a factor of externalizing problems. Thus, the current study assessed how parental marital discord moderates genetic and environmental variance on offspring externalizing problems at two different ages: childhood and late adolescence. That is, the magnitude of genetic and environmental influences on offspring externalizing at ages 11 and 17 was examined as a function of parental marital discord. Consistent with a diathesis–stress model of psychopathology, it was hypothesized that with increasing marital discord, genetic influences on externalizing would be more pronounced. Rather, results indicated that for the 11-year-old sample, nonshared environmental influences were greater when parental marital discord was low, and comparatively, shared environmental influences contributed more to the variance in externalizing problems when parental marital discord was high. No moderation was found for the 17-year-old cohort. In contrast to studies that do not find an effect of the shared environment, these results provide evidence that the common rearing environment has an impact on externalizing problems in preadolescent children.
Habitat preferences of breeding Yellow BuntingsEmberiza sulphuratain hilly rural areas following rice field abandonment in northern Japan
Authors: DEGUCHI SHOTA , ISHIHARA YUKIHIRO , MIGUCHI HIDEO 
Published: December 2016

SummaryWe studied the habitat preferences of breeding Yellow BuntingsEmberiza sulphurata, taking into account the effects of paddyfield abandonment in hilly rural areas within the heavy snow region of northern Japan. Across 30 transects located in valley bottoms, we investigated the relationship between Yellow Bunting abundance and landscape characteristics. The results of generalized linear mixed models showed that forest edge density and landslide sites positively affected Yellow Bunting abundance. These habitats were associated with bush vegetation (forest edge, shrub land, and tall grassland) and were adjacent to the forest. Paddyfield abandonment showed a hump-shaped effect with a peak at the middle succession stage, which was covered primarily with tall grass and some shrubs, but the effect on Yellow Bunting abundance was not statistically significant. To conserve Yellow Bunting habitats in hilly rural areas, it is necessary to protect the forest edge and landslide sites from urbanisation and exploitation. It is also necessary to continue crop cultivation in such areas, to maintain the edges between open land and forest. If cultivation can no longer be continued, the abandoned paddyfields should be kept bushy, using reed beds and shrubs, by active management.
Patient, staff, and clinician perspectives on implementing electronic communications in an interdisciplinary rural family health practice
Authors: Chang Feng , Paramsothy Thivaher , Roche Matthew , Gupta Nishi S. 
Published: December 2016

Aim
To conduct an environmental scan of a rural primary care clinic to assess the feasibility of implementing an e-communications system between patients and clinic staff.

Background
Increasing demands on healthcare require greater efficiencies in communications and services, particularly in rural areas. E-communications may improve clinic efficiency and delivery of healthcare but raises concerns about patient privacy and data security.

Methods
We conducted an environmental scan at one family health team clinic, a high-volume interdisciplinary primary care practice in rural southwestern Ontario, Canada, to determine the feasibility of implementing an e-communications system between its patients and staff. A total of 28 qualitative interviews were conducted (with six physicians, four phone nurses, four physicians’ nurses, five receptionists, one business office attendant, five patients, and three pharmacists who provide care to the clinic’s patients) along with quantitative surveys of 131 clinic patients.

Findings
Patients reported using the internet regularly for multiple purposes. Patients indicated they would use email to communicate with their family doctor for prescription refills (65% of respondents), appointment booking (63%), obtaining lab results (60%), and education (50%). Clinic staff expressed concerns about patient confidentiality and data security, the timeliness, complexity and responsibility of responses, and increased workload.

Conclusion
Clinic staff members are willing to use an e-communications system but clear guidelines are needed for successful adoption and to maintain privacy of patient health data. E-communications might improve access to and quality of care in rural primary care practices.
Explicitly incorporating virtues into actuarial education
Authors: Asher Anthony 
Published: December 2016

AbstractThis paper outlines a framework for explicitly including ethics in actuarial education. The framework includes integrity, the cardinal virtues (justice, prudence, self-control and courage), and vocation. It is based on a traditional understanding of ethics, and it is argued that it has the potential to be widely acceptable. Justification, from philosophy, is found mainly in virtue ethics, and the work of Alasdair MacIntyre. The framework is concerned with matters of character as well as behaviour and ultimate outcomes (which are the respective concerns of apparently competing deontological and teleological theories). Integrity and the cardinal virtues can be found within current professional standards or, it is argued in the case of courage, should be there. We come to appreciate and display the virtues as we are inducted into a professional community by teachers and mentors. Our view of ethics is incomplete, however, without acknowledgement of our own weaknesses and failures, and an understanding of the role of regulation. Such understanding should include insight into the way in which ideologies and institutions can pervert ethics for the benefit of vested interests. Finally, suggestions are made as to how the framework of the virtues can be included in the actuarial syllabuses.
Litigating Extraterritorial Nuisances under English Common Law and UK Statute
Authors: Blanco Elena Merino , Pontin Ben 
Published: December 2016

AbstractEnglish common law and United Kingdom legislation provide various – overall liberal – jurisdictional grounds for hearing foreign tort claims. The article examines these grounds with reference to recent and ongoing oil pollution nuisance litigation involving Royal Dutch Shell Plc and its Nigerian subsidiary operating in the Niger Delta. Particular attention is given to the factors taken into account by the court in exercising its discretion to allow service out of the jurisdiction in cases of pollution taking place abroad under the principle offorum non conveniens. Following the widely commented decision of the United States Supreme Court inKiobelv.Royal Dutch Petroleum Corporation, which ruled against the extraterritorial application of the Alien Tort Statute, it is easy to forget that the rules of jurisdiction vary from country to country and that different legal systems apply similar concepts in often radically different ways. Attention is also given to the future development of English jurisdictional law and practice in the context of environmental nuisance.
Perceptual restoration of masked speech in human cortex
Authors: Leonard Matthew K. , Baud Maxime O. , Sjerps Matthias J. , Chang Edward F. 
Published: December 2016

AbstractHumans are adept at understanding speech despite the fact that our natural listening environment is often filled with interference. An example of this capacity is phoneme restoration, in which part of a word is completely replaced by noise, yet listeners report hearing the whole word. The neurological basis for this unconscious fill-in phenomenon is unknown, despite being a fundamental characteristic of human hearing. Here, using direct cortical recordings in humans, we demonstrate that missing speech is restored at the acoustic-phonetic level in bilateral auditory cortex, in real-time. This restoration is preceded by specific neural activity patterns in a separate language area, left frontal cortex, which predicts the word that participants later report hearing. These results demonstrate that during speech perception, missing acoustic content is synthesized online from the integration of incoming sensory cues and the internal neural dynamics that bias word-level expectation and prediction.
Magmas near the critical degassing pressure drive volcanic unrest towards a critical state
Authors: Chiodini Giovanni , Paonita Antonio , Aiuppa Alessandro , Costa Antonio , Caliro Stefano , De Martino Prospero , Acocella Valerio , Vandemeulebrouck Jean 
Published: December 2016

AbstractDuring the reawaking of a volcano, magmas migrating through the shallow crust have to pass through hydrothermal fluids and rocks. The resulting magma–hydrothermal interactions are still poorly understood, which impairs the ability to interpret volcano monitoring signals and perform hazard assessments. Here we use the results of physical and volatile saturation models to demonstrate that magmatic volatiles released by decompressing magmas at a critical degassing pressure (CDP) can drive volcanic unrest towards a critical state. We show that, at the CDP, the abrupt and voluminous release of H2O-rich magmatic gases can heat hydrothermal fluids and rocks, triggering an accelerating deformation that can ultimately culminate in rock failure and eruption. We propose that magma could be approaching the CDP at Campi Flegrei, a volcano in the metropolitan area of Naples, one of the most densely inhabited areas in the world, and where accelerating deformation and heating are currently being observed.
Energy dissipation from a correlated system driven out of equilibrium
Authors: Rameau J. D. , Freutel S. , Kemper A. F. , Sentef M. A. , Freericks J. K. , Avigo I. , Ligges M. , Rettig L. , Yoshida Y. , Eisaki H. , Schneeloch J. , Zhong R. D. , Xu Z. J. , Gu G. D. , Johnson P. D. , Bovensiepen U. 
Published: December 2016

AbstractIn complex materials various interactions have important roles in determining electronic properties. Angle-resolved photoelectron spectroscopy (ARPES) is used to study these processes by resolving the complex single-particle self-energy and quantifying how quantum interactions modify bare electronic states. However, ambiguities in the measurement of the real part of the self-energy and an intrinsic inability to disentangle various contributions to the imaginary part of the self-energy can leave the implications of such measurements open to debate. Here we employ a combined theoretical and experimental treatment of femtosecond time-resolved ARPES (tr-ARPES) show how population dynamics measured using tr-ARPES can be used to separate electron–boson interactions from electron–electron interactions. We demonstrate a quantitative analysis of a well-defined electron–boson interaction in the unoccupied spectrum of the cuprate Bi2Sr2CaCu2O8+x characterized by an excited population decay time that maps directly to a discrete component of the equilibrium self-energy not readily isolated by static ARPES experiments.
Conformation-driven quantum interference effects mediated by through-space conjugation in self-assembled monolayers
Authors: Carlotti Marco , Kovalchuk Andrii , Wächter Tobias , Qiu Xinkai , Zharnikov Michael , Chiechi Ryan C. 
Published: December 2016

AbstractTunnelling currents through tunnelling junctions comprising molecules with cross-conjugation are markedly lower than for their linearly conjugated analogues. This effect has been shown experimentally and theoretically to arise from destructive quantum interference, which is understood to be an intrinsic, electronic property of molecules. Here we show experimental evidence of conformation-driven interference effects by examining through-space conjugation in which π-conjugated fragments are arranged face-on or edge-on in sufficiently close proximity to interact through space. Observing these effects in the latter requires trapping molecules in a non-equilibrium conformation closely resembling the X-ray crystal structure, which we accomplish using self-assembled monolayers to construct bottom-up, large-area tunnelling junctions. In contrast, interference effects are completely absent in zero-bias simulations on the equilibrium, gas-phase conformation, establishing through-space conjugation as both of fundamental interest and as a potential tool for tuning tunnelling charge-transport in large-area, solid-state molecular-electronic devices.
Super-resolution imaging of light–matter interactions near single semiconductor nanowires
Authors: Johlin Eric , Solari Jacopo , Mann Sander A. , Wang Jia , Shimizu Thomas S. , Garnett Erik C. 
Published: December 2016

AbstractNanophotonics is becoming invaluable for an expanding range of applications, from controlling the spontaneous emission rate and the directionality of quantum emitters, to reducing material requirements of solar cells by an order of magnitude. These effects are highly dependent on the near field of the nanostructure, which constitutes the evanescent fields from propagating and resonant localized modes. Although the interactions between quantum emitters and nanophotonic structures are increasingly well understood theoretically, directly imaging these interactions experimentally remains challenging. Here we demonstrate a photoactivated localization microscopy-based technique to image emitter-nanostructure interactions. For a 75 nm diameter silicon nanowire, we directly observe a confluence of emission rate enhancement, directivity modification and guided mode excitation, with strong interaction at scales up to 13 times the nanowire diameter. Furthermore, through analytical modelling we distinguish the relative contribution of these effects, as well as their dependence on emitter orientation.