bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conditions of Proper Interaction of Low-Pressure Injection Piles (LIP) with Structure and Soil, Carrying Capacity of Pile Anchorage in Foundation
Authors: Pachla Henryk 
Published: February 2017

AbstractThe formation of a pile in the existing foundation and soil creates a new foundation construction which has a structure of foundation-pile-soil. This construction must be able to transfer loads from the foundation to the pile and from the pile to the soil.The pile structure has to transfer an imposed load. From the point of view of continuum mechanics determination of the capacity of such a system is preceded by the analysis of contact problem of three contact surfaces. Each of these surfaces is determined by different pairs of materials. The pair which creates a pile anchorage is a material from which the foundation is built (structure of stone and grout, brick and grout, concrete or reinforced concrete and grout. The pile structure is formed by grout and steel rebar. The pile formed in soil is created by a pair of grout and soil. What is important is that on contact surfaces the materials adhering to one another are subjected to different deformation types that are controlled by mechanical properties and geometry of these surfaces.In the paper, additional conditions that should be fulfilled for the foundation-pile-soil system to make load transfer from foundation to soil possible and safe are presented. The results of research done by the author on foundation-pile contact surface are discussed. The tests were targeted at verifying the bearing capacity of anchorage and deformation of piles made of grout and other materials from which foundations are built. The specimens were tested in tension and compression. The experiments were conducted on the amount specimens which is regarded as small sample to enable the statistical analysis of the results.
Stress-Dilatancy for Soils. Part II: Experimental Validation for Triaxial Tests
Authors: Szypcio Zenon 
Published: February 2017

Abstract
Different forms of the stress-dilatancy relations obtained based on the frictional theory for the triaxial condition are presented. The analysed test data show that the shear resistance of many soils is purely frictional. The angle Φ0 represents the resistance of the soil as a combined effect of sliding and particle rolling on the macro-scale during shear at the critical frictional state. The stress-plastic dilatancy relations differ not only for triaxial compression and extension but also for drained and undrained conditions. The experiment investigated shows the correctness of the frictional state theory in the triaxial condition.
Pixying Behavior: A Versatile Real-Time andPost HocAutomated Optical Tracking Method for Freely Moving and Head Fixed Animals
Authors: Nashaat Mostafa A. , Oraby Hatem , Peña Laura Blanco , Dominiak Sina , Larkum Matthew E. , Sachdev Robert N. S. 
Published: February 2017

AbstractHere, we describe an automated optical method for tracking animal behavior in both head-fixed and freely moving animals, in real time and offline. It takes advantage of an off-the-shelf camera system, the Pixy camera, designed as a fast vision sensor for robotics that uses a color-based filtering algorithm at 50 Hz to track objects. Using customized software, we demonstrate the versatility of our approach by first tracking the rostro-caudal motion of individual adjacent row (D1, D2) or arc whiskers (β, γ), or a single whisker and points on the whisker pad, in head-fixed mice performing a tactile task. Next, we acquired high-speed video and Pixy data simultaneously and applied the pixy-based real-time tracking to high-speed video data. With this approach, we expand the temporal resolution of the Pixy camera and track motion (post hoc) at the limit of high-speed video frame rates. Finally, we show that this system is flexible: it can be used to track individual whisker or limb position without any sophisticated object tracking algorithm, it can be used in many lighting conditions including infrared (IR); it can be used to track head rotation and location of multiple animals simultaneously. Our system makes behavioral monitoring possible in virtually any biological setting.
Daptomycin for Complicated Skin Infections: A Randomized Trial
Authors: Bradley John , Glasser Chad , Patino Hernando , Arnold Sandra R. , Arrieta Antonio , Congeni Blaise , Daum Robert S. , Kojaoghlanian Tsoline , Yoon Minjung , Anastasiou Diane , Wolf Dominik J. , Bokesch Paula 
Published: February 2017

BACKGROUND:
Complicated skin and skin structure infections (cSSSI) are common in children. Due to safety and resistance issues with recommended agents, new treatment options would be advantageous.

METHODS:
Multicenter, evaluator-blinded clinical trial. Patients 1 to 17 years old with cSSSI caused by Gram-positive pathogens were randomized 2:1 to intravenous daptomycin or standard-of-care (SOC) treatment for ≤14 days. Daptomycin was administered once daily with dosing by patient age: 12 to 17 years, 5 mg/kg; 7 to 11 years, 7 mg/kg; 2 to 6 years, 9 mg/kg; 12 to 23 months, 10 mg/kg. The primary objective was to evaluate daptomycin safety. The secondary objective was to assess the efficacy of daptomycin compared with SOC. The intent-to-treat (ITT) population consisted of all randomized patients with any dose of study drug.

RESULTS:
The ITT population comprised 257 daptomycin and 132 SOC patients (primarily clindamycin or vancomycin); 35% had confirmed methicillin-resistant Staphylococcus aureus. The most common adverse events were diarrhea (7% daptomycin, 5% SOC) and increased creatine phosphokinase (6% daptomycin, 5% SOC). The proportions of safety population patients with treatment-related adverse events were similar between the daptomycin (14%) and SOC (17%) groups. Clinical success rates (blinded evaluator–assessed complete/partial resolution of cSSSI signs and symptoms 7–14 days after end-of-treatment) in the ITT population were also similar for the daptomycin (91%) and SOC groups.

CONCLUSIONS:
Once-daily daptomycin was well tolerated, with safety and efficacy comparable to SOC in children/adolescents with cSSSI caused by Gram-positive pathogens, including community-acquired methicillin-resistant S aureus.
Factorial validity of the Problematic Facebook Use Scale for adolescents and young adults
Authors: Marino Claudia , Vieno Alessio , Altoè Gianmarco , Spada Marcantonio M. 
Published: February 2017

Background and aims
Recent research on problematic Facebook use has highlighted the need to develop a specific theory-driven measure to assess this potential behavioral addiction. The aim of the present study was to examine the factorial validity of the Problematic Facebook Use Scale (PFUS) adapted from Caplan’s Generalized Problematic Internet Scale model.

Methods
A total of 1,460 Italian adolescents and young adults (aged 14–29 years) participated in the study. Confirmatory factor analyses were performed in order to assess the factorial validity of the scale.

Results
Results revealed that the factor structure of the PFUS provided a good fit to the data. Furthermore, results of the multiple group analyses supported the invariance of the model across age and gender groups.

Discussion and conclusions
This study provides evidence supporting the factorial validity of the PFUS. This new scale provides a theory-driven tool to assess problematic use of Facebook among male and female adolescents and young adults.
Ryzyko starości a dodatkowy system emerytalny w Polsce
Authors: Jedynak Tomasz 
Published: February 2017

The article examines the use of a supplementary pension scheme in Poland to insure against old-age risk. The following hypothesis was verified: In order to effectively manage the risks that attend aging, the rules governing third pillar instruments in Poland must be changed. To this end, the old-age risk was characterised and the rules governing the third pillar instruments were analysed, as were the current state and use of those instruments. No grounds to reject the research hypothesis were found, though the desirable direction of changes in the functioning of these instruments is indicated. In addition, the importance of education about pension systems is emphasised.
Weryfikacja przydatności modelu CAPM do wyceny instrumentów finansowych. Zastosowanie portfela zero-beta przy szacowaniu stopy wolnej od ryzyka
Authors: Kasolik Michał 
Published: February 2017

The article describes the issue of capital asset pricing using Capital Assets Pricing Models (CAPM). The theoretical section presents the assumptions, zero-beta portfolio modification and results of using CAPM. The empirical part focuses on studies of the effectiveness of the CAPM model. Empirical tests are given, providing evidence that both denies and confirms the findings of the CAPM model, while the correlation coefficient is used to verify the model on the Polish capital market. The zero-beta portfolio was created based on futures contracts on WIG20 and units of the Multi Units Luxembourg Lyxor. As indicated by the results, this portfolio may be an appropriate method for estimating the risk-free interest rate. Research on the effectiveness of the valuation was carried out on the basis of two companies: KGHM Polska Miedź SA and Próchnik SA. The results of the study show that in most cases the variability of the companies’ returns is greater than that resulting from the CAPM model.
A Phase I/IIa Study of DHP107, a Novel Oral Paclitaxel Formulation, in Patients with Advanced Solid Tumors or Gastric Cancer
Authors: Ryu Min-Hee , Ryoo Baek-Yeol , Kim Tae Won , Kim Sung Bae , Lim Hyeong-Seok , Bae Kyun-Seop , Park Sook Ryun , Jo Yeong-Woo , Cho Hyun Ju , Kang Yoon-Koo 
Published: February 2017

AbstractLessons LearnedIdeally, patients should have access to an oral formulation of paclitaxel, as well as an intravenous formulation, to allow development of regimens exploring alternate schedules and to avoid reactions to Cremophor EL (BASF Corp., Ludwigshafen, Germany, https://www.basf.com). DHP107 is a novel oral paclitaxel formulation that is a tolerable and feasible regimen for patients with gastric cancer, with data suggesting efficacy similar to that of intravenous paclitaxel.BackgroundWe evaluated the maximum tolerated dose (MTD) of DHP107, a novel oral paclitaxel formulation, and the efficacy and safety of the agent in patients with advanced solid tumors.Patients and MethodsPhase I study: cohorts of 3–6 patients with advanced solid tumors received escalating DHP107 doses. Phase IIa study: patients with measurable advanced gastric cancer received DHP107, 200 mg/m2 b.i.d., on days 1, 8, and 15 every 4 weeks. Pharmacokinetics, safety, and efficacy were analyzed.ResultsPhase I: 17 patients received a dose-escalating regimen of DHP107, 150–250 mg/m2 b.i.d. Dose-limiting toxicities were neutropenia and febrile neutropenia. The MTD (recommended dose) for phase IIa was 200 mg/m2 b.i.d. Phase IIa: 11 patients with measurable advanced gastric cancer in whom first-line therapy failed received DHP107 (MTD). Three confirmed partial responses were observed. Median progression-free survival of gastric cancer patients (n = 16) treated at the MTD was 2.97 (95% confidence interval, 1.67–5.40) months (Fig. 1). The most frequent grade 3/4 adverse events were neutropenia (35.3%) and leukopenia (17.6%) at the MTD (phase I and IIa combined; n = 17).ConclusionDHP107 showed good antitumor efficacy and was tolerable. The MTD (200 mg/m2 b.i.d.) is recommended for use in further studies comparing DHP107 with standard intravenous paclitaxel therapy.
Un caso notable de traducción indirecta: The Last of the Mohicans de Feminore Cooper traducido por Vicente Pagasartundua a través del francés
Authors: García Calderón Ángeles , Martínez Ojeda Beatriz 
Published: February 2017

En el mundo de la traducción la figura del traductor se identifica de tal modo con la del autor del texto original, que alcanza a veces un mimetismo absoluto con él. Huelga decir que la relación parece lógica entre el novelista y el traductor, pero es más sorprendente cuando ocurre entre un ‘versionista’ del traductor y el original que traduce; este es el caso del español Pagasartundua, que versiona una novela americana a través de la traducción francesa de Defauconpret. Si Jean-Baptiste Defauconpret es reconocido por la crítica como el ‘intermediario’ en Francia de Walter Scott y feminore Cooper, Pagasartundua será quien dé a conocer al novelista americano a los lectores españoles, a través del filtro del prestigioso traductor francés.
RESENHA BARATA, R. B. Como e por que as desigualdades sociais fazem mal à saúde. Rio de Janeiro: Editora da FIOCRUZ, 2009. (Coleção Temas de Saúde)
Authors: De Andreazzi Maria de Fátima Siliansky 
Published: February 2017

A Saúde Coletiva brasileira é uma herdeira do movimento de crítica a uma concepção do processo saúde-doença decorrente de interações biológicas do tipo agente-hospedeiro ou decorrente de uma multiplicidade não hierarquizada de fatores de risco. Nessa crítica, formulada durante os tormentosos anos 60 e desenvolvida nos vinte anos seguintes por intelectuais da América Latina. De proeminência científica incontestável, o social deixa de ser mais um fator de risco cuja relação com as doenças está por ser estabelecida com significância estatística. O social, na sua historicidade e, portanto, na sua potencialidade de mudança, é a própria determinação do processo, deixando de poder existir uma história natural, mas uma história social da doença.
The Use of the h-Index in Academic Orthopaedic Surgery
Authors: Bastian Sevag , Ippolito Joseph A. , Lopez Santiago A. , Eloy Jean Anderson , Beebe Kathleen S. 
Published: February 2017

Background:
The Hirsch index (h-index), widely considered a valuable measure of assessing academic productivity, has been studied in various medical and surgical specialties and has shown strong associations between higher h-indices and academic promotion, as well as with National Institutes of Health (NIH) awards. Additionally, the m-index and e-index may complement the h-index in this assessment of merit. The purpose of this study was to investigate the relationship between the h, m, and e-indices and academic rank for 2,061 academic orthopaedic surgeons in the United States.

Methods:
The h-indices of faculty members from 120 academic orthopaedic surgery residency programs were organized and calculated using the Scopus and Google Scholar databases. Additionally, m-index and e-index scores were calculated from Google Scholar. After application of exclusion criteria, 2,061 academic orthopaedic surgeons were included.

Results:
Academic rank (assistant professor, associate professor, professor, and chair) increases as mean h-index, m-index, and e-index scores increase. Among 976 assistant professors, 504 associate professors, 461 professors, and 120 chairs, mean h, m, and e-indices increased with each academic rank. In the comparison of male and female surgeons, there was no significant difference in h, m, or e-index scores, with the exception of increased h-index scores among male assistant professors.

Conclusions:
Scholarly impact, as defined by academic productivity and scientific relevance, can be classified by the h-index and supplemented by the m and e-indices. This study has revealed well-defined differences in h, m, and e-indices with regard to academic rank among orthopaedic surgeons. Although the h, m, and e-indices may be of value as adjunct assessment devices for scholarly merit, careful consideration of their limitations must be maintained.
Physical Activities and Lifestyle Factors Related to Adolescent Idiopathic Scoliosis
Authors: Watanabe Kota , Michikawa Takehiro , Yonezawa Ikuho , Takaso Masashi , Minami Shohei , Soshi Shigeru , Tsuji Takashi , Okada Eijiro , Abe Katsumi , Takahashi Masamichi , Asakura Keiko , Nishiwaki Yuji , Matsumoto Morio 
Published: February 2017

Background:
In addition to genetic factors, environmental and lifestyle factors are thought to play an important role in the onset of adolescent idiopathic scoliosis (AIS). This cross-sectional study was conducted to explore lifestyle factors related to AIS.

Methods:
This study included 2,759 Japanese female junior high school students who planned a secondary screening after an initial moiré topography screening indicated possible scoliosis. The students and their mothers, or guardians, were asked to fill out a questionnaire consisting of 38 questions about demographic factors, lifestyle-related factors, social factors, household environment, participation in sports, health status, and factors related to the mother’s pregnancy and delivery. The questionnaire was completed by 2,747 students (a 99.6% response rate). After excluding students with heart disease, neurological disease, or a congenital vertebral anomaly, 2,600 students were eligible for assessment. After undergoing a secondary screening with standing radiographs of the spine, students were assigned to the normal (control) group if radiographs showed a curve of <15° or to the scoliosis group if they had a curve of ≥15°. The odds ratios (ORs) for AIS in relation to the possible risk or preventive factors were estimated by logistic regression analyses.

Results:
No lifestyle-related factor was significantly associated with AIS. However, AIS was associated with classical ballet training (OR, 1.38; 95% confidence interval [CI], 1.09 to 1.75); the odds of AIS developing increased as the child’s frequency of training, number of years of experience, and duration of training in ballet increased. The OR for AIS was 1.5 times higher for participants whose mothers had scoliosis. AIS was also associated with a low body mass index (BMI). These associations remained even after mutual adjustment was performed.

Conclusions:
No association was found between AIS and lifestyle-related factors. However, classical ballet training, a family history of scoliosis, and low BMI may be associated with AIS.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Perivascular Stem Cells Diminish Muscle Atrophy Following Massive Rotator Cuff Tears in a Small Animal Model
Authors: Eliasberg Claire D. , Dar Ayelet , Jensen Andrew R. , Murray Iain R. , Hardy Winters R. , Kowalski Tomasz J. , Garagozlo Cameron A. , Natsuhara Kyle M. , Khan Adam Z. , McBride Owen J. , Cha Peter I. , Kelley Benjamin V. , Evseenko Denis , Feeley Brian T. , McAllister David R. , Péault Bruno , Petrigliano Frank A. 
Published: February 2017

Background:
Rotator cuff tears are a common cause of shoulder pain and often necessitate operative repair. Muscle atrophy, fibrosis, and fatty infiltration can develop after rotator cuff tears, which may compromise surgical outcomes. This study investigated the regenerative potential of 2 human adipose-derived progenitor cell lineages in a murine model of massive rotator cuff tears.

Methods:
Ninety immunodeficient mice were used (15 groups of 6 mice). Mice were assigned to 1 of 3 surgical procedures: sham, supraspinatus and infraspinatus tendon transection (TT), or TT and denervation via suprascapular nerve transection (TT + DN). Perivascular stem cells (PSCs) were harvested from human lipoaspirate and sorted using fluorescence-activated cell sorting into pericytes (CD146+ CD34− CD45− CD31−) and adventitial cells (CD146− CD34+ CD45− CD31−). Mice received no injection, injection with saline solution, or injection with pericytes or adventitial cells either at the time of the index procedure (“prophylactic”) or at 2 weeks following the index surgery (“therapeutic”). Muscles were harvested 6 weeks following the index procedure. Wet muscle weight, muscle fiber cross-sectional area, fibrosis, and fatty infiltration were analyzed.

Results:
PSC treatment after TT (prophylactic or therapeutic injections) and after TT + DN (therapeutic injections) resulted in less muscle weight loss and greater muscle fiber cross-sectional area than was demonstrated for controls (p < 0.05). The TT + DN groups treated with pericytes at either time point or with adventitial cells at 2 weeks postoperatively had less fibrosis than the TT + DN controls. There was less fatty infiltration in the TT groups treated with pericytes at either time point or with adventitial cells at the time of surgery compared with controls.

Conclusions:
Our findings demonstrated significantly less muscle atrophy in the groups treated with PSCs compared with controls. This suggests that the use of PSCs may have a role in the prevention of muscle atrophy without leading to increased fibrosis or fatty infiltration.

Clinical Relevance:
Improved muscle quality in the setting of rotator cuff tears may increase the success rates of surgical repair and lead to superior clinical outcomes.
Innovative Conveyance System Saves $9.4M on a Deep Water, High Angle Well in the Nam Con Son Basin
Authors: Folger Michael , McCormick Stephen , Sarian Serko 
Published: February 2017

Abstract
Due to adverse hole conditions, Operators in the Nam Con Son Basin have had difficulties carrying out their wireline logging programs. Unplanned wiper trips and pipe conveyed logging have often been necessary to acquire log data. These remedies are expensive and time consuming and lead to substantial inefficiencies during execution. In search for operational efficiency, a revolutionary conveyance technology was used with the wireline logging tools.
The conveyance system consists of wheeled carriages which are secured to the exterior of the logging tool housings and aligned at regularly spaced intervals. The carriages have large diameter wheels with an active bearing lubrication system and carry the tool-string over and above wellbore cuttings. The wheels significantly reduce tool drag, facilitating conventional logging in very high angle wells. The carriwages orientate the logging tool sensors to enhance sample recovery and data quality. The holefinder consists of an upturned nose cone, analogous to a ski tip, which effortlessly slides over ledges without stopping.
The intermediate logging operation continued over 5 days, during which 5 runs were made with up to nine carriages and a hole-finder on each tool string. All tool-strings ran seamlessly to TD and logged out smoothly without issues, facilitating excellent data acquisition. Following success in the intermediate hole section, the conveyance system was deployed on all wireline runs in both the main wellbore and sidetrack with similar results. The conveyance devices allowed the drilling and exploration team to achieve all of the pre-drill objectives while eliminating the unplanned costs experienced with previous logging programs. The conveyance system provides a cost effective method for managing high deviation wellbores while enhancing the operator's data acquisition needs for exploration evaluation. By avoiding pipe conveyed logging and wiper trips, 11 days of rig time was saved on a floating rig, with associated cost savings of USD 9.4M.
Together, these complimentary devices form a complete conveyance system that uniquely resolve all the challenges that have plagued wireline logging for over 50 years while enhancing data quality. The technology also has applications in well intervention operations.