bluuebunny/crossref_metadata_2025_split huggingface dataset:
Herramientas para el autoaprendizaje en procesos creativos y de prototipo de interfaces para la gestión de contenido audiovisual. El caso de VertexZenit.
Authors: Vertedor-Romero Jose Antonio , Ruiz del Olmo Francisco Javier , Alonso-Calero Jose María 
Published: July 2017

VertexZenit es un proyecto desarrollado en el ámbito universitario de la enseñanza de las Bellas Artes en la Universidad de Málaga, España, con un componente artístico-investigador de larga duración basado en la programación de comportamientos audiovisuales y en la construcción de interfaces y su comunicación con la máquina. La evolución de la investigación muestra que tanto la tecnología como la programación aplicada pueden tener aplicación en distintos ámbitos sociales mediante un uso alternativo de la misma. Se han construido máquinas interactivas propias que pueden mutar según las necesidades de su entorno como parte del trabajo desarrollado. El estudio se centra en tres aspectos temáticos: el trabajo de diseño tanto virtual como físico de estas interfaces (tanto para elaborar música electrónica y como video auto-generado), la participación como elemento de producción y finalmente la posibilidad de un repositorio de conocimiento colectivo. Estas tres ideas quedan formalizadas a través de distintos prototipos con los que se ha experimentado en los últimos años y que se recogen como conclusiones generales del presente texto. Enviado em: 29 de outubro de 2016. Aprovado em: 22 de fevereiro de 2017
Clinical Preceptors’ Perceptions of Empathy: The Empathy in Osteopathic Training and Education (EMOTE) Study
Authors: Davis Glenn Elbert , Hartwig Walter Carl , McTighe Adam J. 
Published: July 2017

Abstract

Context
Physician empathy influences rapport with patients and improves outcomes, but it is not well understood as an outcome of osteopathic medical education.

Objective
To determine how clerkship preceptors at Touro University College of Osteopathic Medicine-CA (TUCOM) in Vallejo define empathy and how they compare observed empathetic behavior of TUCOM students with that of other medical students.

Methods
Cross-sectional data were obtained from a survey of TUCOM clinical preceptors comparing TUCOM students with other medical students on 10 behaviors. Results were analyzed with a 2-tailed z test of proportional difference at the 95% confidence level.

Results
Of 650 preceptors contacted, 177 responded and were included in the final analysis (27%). Survey item reliability was high (Cronbach α=0.96). A majority of preceptors (59% to 71%) considered TUCOM students “similar” to other medical students for each behavior. A majority of preceptors (107 [60%]) shared a definition of empathy with one another and with the National Board of Osteopathic Medical Examiners and the American Association of Colleges of Osteopathic Medicine. Approximately 39% of preceptors rated TUCOM students “better” or “advanced” for “displays of empathy” compared with approximately 30% of preceptors who rated students as better or advanced across all 10 behaviors. Preceptors who shared a definition of empathy rated TUCOM students as better or advanced at a significantly higher rate for “displays of empathy” (z=1.982, P<.05) compared with preceptors who did not share a definition (n=70). Osteopathic preceptors (n=67) rated TUCOM students significantly higher on “displays of empathy” (z=2.82, P<.05) and “clear and effective communication to patients, families and co-workers” (z=2.83, P<.01) than did allopathic preceptors. No significant differences were found based on number of years as a preceptor or on the combination of types of students the preceptor taught.

Conclusion
Most clinical preceptors shared a definition of empathy, and they were able to observe and rate displays of it in clerkship students. Preceptors rated TUCOM students more favorably than other students they taught for displays of empathy.
Functional Somatic Syndrome: Assessment and Management
Authors: Graver Christopher J. 
Published: July 2017

Abstract
Functional somatic syndrome (FSS) occurs in as many as 30% of patients in general medical practice, but it is infrequently a topic of formal instruction. Many physicians feel uncomfortable with medically unexplained symptoms and are unfamiliar with how to assess or manage them. Traditional medical approaches can be ineffective and can contribute to iatrogenic or adverse physiologic effects in patients. Physicians treating patients with FSS should not only consider standard medical tests, but they should also try to gain a deeper behavioral understanding of the mind-body connections that underlie the presenting symptoms. Osteopathic physicians, with their emphasis on holistic patient care, are in a key position to treat patients with FSS. This review provides a brief recapitulation of the literature and illustrates key factors in the assessment and management of FSS.
Ready for Residency: A Bloomian Analysis of Competency-Based Osteopathic Medical Education
Authors: Rosenberger Kyle , Skinner Daniel , Monk Jody 
Published: July 2017

Abstract

Context
Bloom's Taxonomy is a widely accepted tool for analyzing learning objectives, creating assessment materials, and ensuring that students move progressively through various levels of knowledge and cognition. Competency-based osteopathic medical education has, to the authors’ knowledge, yet to be subjected to systematic bloomian analysis.

Objective
To advance a bloomian analysis of competencies published by the American Association of Colleges of Osteopathic Medicine (AACOM) and draw consequences of that analysis for undergraduate osteopathic medical education.

Methods
Content analysis of the verbs and contexts used in the AACOM competencies was conducted, followed by categorization by the various cognitive and knowledge dimensions as specified by the Revised Bloom's Taxonomy.

Results
The majority of AACOM competencies gravitate toward the taxonomy's apply and procedural cognitive and knowledge dimensions, respectively. In addition, 58% of the top 10 most-used verbs in the document were identified to be in the apply cognitive dimension. An analysis of the competencies revealed that 69% can be categorized under the procedural knowledge dimension. Of 657 code co-occurances, 45% were from the apply cognitive and procedural knowledge dimensions. These figures suggest a skewing toward application-based cognitive and procedural-based knowledge over other types of cognitive and knowledge dimensions.

Conclusion
Bloom's Taxonomy offers a useful framework for understanding how competency-based osteopathic medical education is organized. Such analysis underscores the importance of attending to the language and construction of competencies to better understand how the language of competencies shapes pedagogic practices and begin a broader conversation about the appropriate use and distribution of lower- and higher-order cognitive processes within competency-based osteopathic medical education.
Pheochromocytoma-Induced Cardiomyopathy Mimicking Acute Coronary Syndrome
Authors: Vilcant Viliane 
Published: July 2017

Abstract
Pheochromocytoma is a rare catecholamine-secreting tumor with a prevalence of 0.1% to 0.6% in hypertensive patients. The classic triad of symptoms is headache, palpitations, and diaphoresis, but clinical presentation varies greatly. Pheochromocytoma can also mimic acute coronary syndrome and heart failure. With surgical resection, appropriate preoperative medical therapy, and 10% malignancy rate, prognosis is usually good. In the present case, a patient presented to the emergency department with symptoms suggesting a non–ST-segment elevation myocardial infarction and was transferred to a tertiary medical center for a cardiac catheterization. No coronary artery disease was found. However, cardiomyopathy developed, which made pheochromocytoma difficult to diagnose at first glance.
Landscape metrics as functional traits in plants: perspectives from a glacier foreland
Authors: Sitzia Tommaso , Dainese Matteo , Krüsi Bertil O. , McCollin Duncan 
Published: July 2017

Spatial patterns of vegetation arise from an interplay of functional traits, environmental characteristics and chance. The retreat of glaciers offers exposed substrates which are colonised by plants forming distinct patchy patterns. The aim of this study was to unravel whether patch-level landscape metrics of plants can be treated as functional traits. We sampled 46 plots, each 1 m × 1 m, distributed along a restricted range of terrain age and topsoil texture on the foreland of the Nardis glacier, located in the South-Eastern Alps, Italy. Nine quantitative functional traits were selected for 16 of the plant species present, and seven landscape metrics were measured to describe the spatial arrangement of the plant species’ patches on the study plots, at a resolution of 1 cm × 1 cm. We studied the relationships among plant communities, landscape metrics, terrain age and topsoil texture. RLQ-analysis was used to examine trait-spatial configuration relationships. To assess the effect of terrain age and topsoil texture variation on trait performance, we applied a partial-RLQ analysis approach. Finally, we used the fourth-corner statistic to quantify and test relationships between traits, landscape metrics and RLQ axes. Floristically-defined relevé clusters differed significantly with regard to several landscape metrics. Diversity in patch types and size increased and patch size decreased with increasing canopy height, leaf size and weight. Moreover, more compact patch shapes were correlated with an increased capacity for the conservation of nutrients in leaves. Neither plant species composition nor any of the landscape metrics were found to differ amongst the three classes of terrain age or topsoil texture. We conclude that patch-level landscape metrics of plants can be treated as species-specific functional traits. We recommend that existing databases of functional traits should incorporate these type of data.
Toward Flexible Wireless Pressure‐Sensing Device via Ionic Hydrogel Microsphere for Continuously Mapping Human‐Skin Signals
Authors: Tai Yanlong , Yang Zhenguo 
Published: July 2017

AbstractFlexible pressure‐sensing systems have attracted more attention recently. Here, a novel kind of flexible wireless pressure‐sensing device is reported based on a chip‐type ionic alginate hydrogel (IAH) microsphere, which is sandwiched by a folded polyethylene terephthalate film with a continuous silver pattern as both antenna and electrode through a stack of double‐sided tape as bonding frame. The whole device can be seen as an inductance (L)/capacitance (C)/resistance (R) (LCR) oscillation circuit and the main sensing mechanism is based on the variation of contact electric double‐layer capacitance (CEDL) at the IAH microsphere/electrode interface. Through theoretical analysis, the performance of the wireless pressure sensor is optimized step by step. Under the defined parameters, the final sensitivity of device is up to 9.32% kPa−1 (to working frequency) with a detectable unit as low as 25 Pa, showing with great repeatability and durability. In addition, the efficiency of this wireless devices is further verified through continuously mapping human‐skin signals (muscle motion at human hand, pulse signals at human wrist), exhibiting excellent sensing performance.
Robotic gastrectomy for gastric cancer: Current evidence
Authors: Alhossaini Rana M. , Altamran Abdulaziz A. , Seo Won Jun , Hyung Woo Jin 
Published: July 2017

AbstractThe robotic system has gained wide acceptance in specialties such as urological and gynecological surgery. It has also been applied in the field of upper gastrointestinal surgery. Since the first implementation of the robotic system for the treatment of gastric adenocarcinoma, the procedure has been found to be safe and feasible. Although robotic gastrectomy does not meet our expectations and yield better results than laparoscopic gastrectomy, this procedure seems to provide several advantages over laparoscopy such as reduced blood loss, shorter learning curves and increased number of retrieved lymph nodes. However, as many case series, including a recent multicenter study, have revealed, higher cost and longer operation time are the major limitations of robotic gastrectomy. Furthermore, there are no results from well‐designed randomized clinical trials comparing the two procedures. New procedures in much more technically demanding cases will test the genuine benefits of robotic gastrectomy.
Land use and mobility during the Neolithic in Wales explored using isotope analysis of tooth enamel
Authors: Neil Samantha , Montgomery Janet , Evans Jane , Cook Gordon T. , Scarre Chris 
Published: July 2017

AbstractObjectivesThe nature of land use and mobility during the transition to agriculture has often been debated. Here, we use isotope analysis of tooth enamel from human populations buried in two different Neolithic burial monuments, Penywyrlod and Ty Isaf, in south‐east Wales, to examine patterns of land use and to evaluate where individuals obtained their childhood diet.Materials and MethodsWe employ strontium (87Sr/86Sr) and oxygen (δ18O) and carbon (δ13C) isotope analysis of enamel from adjacent molars. We compare strontium isotope values measured in enamel to locally bioavailable 87Sr/86Sr values. We combine discussion of these results with evaluation of new radiocarbon dates obtained from both sites.ResultsThe majority of enamel samples from Penywyrlod have strontium isotope ratios above 0.7140. In contrast, the majority of those from Ty Isaf have 87Sr/86Sr values below 0.7140. At Penywyrlod oxygen isotope ratios range between 25.9 and 28.2 ‰ (mean 26.7 ± 0.6 ‰, 1σ, n = 15) and enamel δ13Ccarbonate values range between −18.0 and −15.0 ‰ (mean −16.0 ± 0.8 ‰, 1σ, n = 15). At Ty Isaf oxygen isotope ratios exhibited by Neolithic individuals range between 25.4 and 27.7 ‰ (mean 26.7 ± 0.6 ‰, 1σ, n = 15) and enamel δ13Ccarbonate values range between −16.9 and −14.9 ‰ (mean −16.0 ± 0.6 ‰, 1σ, n = 15).DiscussionThe strontium isotope results suggest that the majority of individuals buried at Penywyrlod did not source their childhood diet locally. One individual in this group has strontium isotope ratios that exceed all current known biosphere values within England and Wales. This individual is radiocarbon dated to the first few centuries of the 4th millennium BC, consistent with the period in which agriculture was initiated in Wales: the results therefore provide evidence for migration during the transition to farming in Wales. In contrast, all individuals sampled from Ty Isaf post‐date the period in which agriculture is considered to have been initiated and could have sourced their childhood diet from the local region in which they were buried.
Shaping Antiaromatic π‐Systems by Metalation: Synthesis of a Bowl‐Shaped Antiaromatic Palladium Norcorrole
Authors: Yonezawa Tsubasa , Shafie Siham A. , Hiroto Satoru , Shinokubo Hiroshi 
Published: July 2017

AbstractThe synthesis of a bowl‐shaped antiaromatic molecule was achieved through the deformation of a planar antiaromatic porphyrinic π‐conjugation system by insertion of palladium into the small cavity of a metal‐free norcorrole. The bowl‐to‐bowl inversion dynamics of the antiaromatic Pd‐coordinated norcorrole was determined by variable‐temperature 1H NMR spectroscopy. The metal‐free norcorrole was prepared from acid‐induced demetalation of a copper norcorrole, which was obtained from the intramolecular coupling of a bis(diiododipyrrin) copper complex with copper thiophenecarboxylate.
Base‐Free Asymmetric Transfer Hydrogenation of 1,2‐Di‐ and Monoketones Catalyzed by a (NH)2P2‐Macrocyclic Iron(II) Hydride
Authors: De Luca Lorena , Mezzetti Antonio 
Published: July 2017

AbstractThe hydride isonitrile complex [FeH(CNCEt3)(1 a)]BF4 (2) containing a chiral P2(NH)2 macrocycle (1 a), in the presence of 2‐propanol as hydrogen donor, catalyzes the base‐free asymmetric transfer hydrogenation (ATH) of prostereogenic ketones to alcohols and the hemihydrogenation of benzils to benzoins, which contain a base‐labile stereocenter. Benzoins are formed in up to 83 % isolated yield with enantioselectivity reaching 95 % ee. Ketones give the same enantioselectivity observed with the parent catalytic system [Fe(CNCEt3)2(1 a)] (3 a) that operates with added NaOtBu.
Hierarchical Nanotubes Constructed by Carbon‐Coated Ultrathin SnS Nanosheets for Fast Capacitive Sodium Storage
Authors: He Peilei , Fang Yongjin , Yu Xin‐Yao , Lou Xiong Wen (David) 
Published: July 2017

AbstractTin(II) sulfide (SnS) has been an attractive anode material for sodium ion batteries. Herein, an elegant templating method has been developed for the rational design and synthesis of hierarchical SnS nanotubes composed of ultrathin nanosheets. In order to enhance the electrochemical performance, carbon coated hierarchical SnS nanotubes (denoted as SnS@C nanotubes) have also been obtained by simply adding glucose into the reaction system. Benefiting from their unique structural merits, the SnS@C nanotubes exhibit enhanced sodium storage properties in terms of good cycling performance and superior rate capability.
Improvements in the thermal conductivity and mechanical properties of phase‐change microcapsules with oxygen‐plasma‐modified multiwalled carbon nanotubes
Authors: Sun Yanli , Wang Rui , Liu Xing , Li Mengxuan , Yang Hua , Li Bo 
Published: July 2017

ABSTRACTThe thermal properties and mechanical properties are the key factors of phase‐change microcapsules (microPCMs) in energy‐storage applications. In this study, microPCMs based on an n‐octadecane (C18) core and a melamine–urea–formaldehyde (MUF) shell supplemented with O2‐plasma‐modified multiwalled carbon nanotubes (CNTs) were synthesized through in situ polymerization. Meanwhile, two different addition methods, the addition of modified CNTs into the emulsion system or into the polymer system, were compared and examined. Scanning electron microscopy micrographs showed that the microPCMs were spherical and had a broadened size distribution. Fourier transform infrared testing demonstrated that the modified CNTs did not affect C18 coated by MUF resin. The results indicate that the thermal conductivity and mechanical properties of the microPCMs were remarkably improved by the addition of a moderate amount of modified CNTs, but the heat enthalpy and encapsulated efficiency decreased slightly. Moreover, the thermal conductivity and mechanical properties of microPCMs modified with CNTs directly added to the polymer system were superior to those with CNTs added to emulsion system. In particular, when 0.2 g of modified CNTs were added to the polymer system, the thermal conductivity of the microPCMs was improved by 225%, and the breakage rates of the microPCMs at 4000 rpm for 5, 10, and 20 min decreased by 74, 72, and 60%, respectively, compared with that of the microPCMs without modified CNTs. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45269.
Improved sensitivity of firefly luminescent intermediate‐based protein interaction assay using Ser 440 mutant with lower adenylation activity
Authors: Ohmuro‐Matsuyama Yuki , Yamashita Takahiro , Lin Huan , Yamaji Hideki , Ueda Hiroshi 
Published: July 2017

AbstractProtein–protein interaction assays are important in various fields including molecular biology, diagnostics, and drug screening. We recently designed a novel protein–protein interaction assay, the firefly luminescent intermediate‐based protein interaction assay (FlimPIA), that exploited the unique reaction mechanism of firefly luciferase (Fluc). Using two mutant Flucs, each impaired with one of the two half‐reactions, namely adenylation and subsequent oxidative luminescent steps, FlimPIA detects the proximity of the two proteins tethered to the mutant Flucs. Here, we found that introducing a mutation into a residue in the hinge region (S440) of the mutant with lowered adenylation activity (‘Acceptor’ Fluc) further improved the response of FlimPIA by lowering the residual adenylation activity. Mutants with bulkier residues showed greater inhibition, probably due to increased steric hindrance at the adenylation conformation. As a result, the FlimPIA with S440 L acceptor showed the best signal/background ratio for the detection of rapamycin‐induced FKBP12–FRB interactions.
A novel moonlight function of glyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) for immunomodulation
Authors: Nakano Toshiaki , Goto Shigeru , Takaoka Yuki , Tseng Hui‐Peng , Fujimura Takashi , Kawamoto Seiji , Ono Kazuhisa , Chen Chao‐Long 
Published: July 2017

AbstractGlyceraldehyde‐3‐phosphate dehydrogenase (GAPDH) is an energy metabolism‐related enzyme, which generates NADH in glycolysis. Our previous study revealed a novel role of exogenous GAPDH in the amelioration of lipopolysaccharide (LPS)‐induced sepsis‐related, severe acute lung injury (ALI) in mice. Here, we show the effect of extracellular GAPDH on the physiological functions of macrophages, which play an important role in the onset of sepsis and ALI. GAPDH has no effect on cell viability, while it strongly suppressed cell adhesion, spreading, and phagocytic function of LPS‐stimulated macrophages. GAPDH treatment significantly reduced tumor necrosis factor (TNF)‐α, while it induced interleukin (IL)‐10 production from LPS‐stimulated macrophages in a dose‐dependent manner. It is noteworthy that heat inactivation of GAPDH lost its immunomodulatory activity. Correspondingly, NADH significantly inhibited TNF‐α and enhanced IL‐10 production with elevation of both M1/M2 macrophage markers. These data suggest that extracellular GAPDH induces intermediate M1/M2 macrophages for termination of inflammation, partly through its enzyme activity for generation of NADH. © 2018 BioFactors, 44(6):597–608, 2018
MOAM: A methodology for developing mobile learning objects (MLOs)
Authors: Saldaña Hernández Karen Annet , Hernández Velázquez Yesenia , López Domínguez Eduardo , Excelente Toledo Cora Beatriz , Medina Nieto María Auxilio 
Published: July 2017

AbstractThis paper proposes a methodology to develop high quality MLOs throughout five phases: analysis, design, development, assessment, and publishing. MOAM was assessed with important results given that MLOs comply with technical aspects such as reusability, interoperability, portability and take into account educational objectives, learning content, assessment, and learning styles.