bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sticking with it: Psychotherapy outcomes for adults with autism spectrum disorder in a university counseling center setting
Authors: Anderberg Emily , Cox Jonathan C. , Neeley Tass E. Shannon , Erekson David M. , Gabrielsen Terisa P. , Warren Jared S. , Cline Jared , Petersen Devin , South Mikle 
Published: August 2017

Young adults with autism spectrum disorders (ASD) experience high rates of comorbid mental health concerns in addition to distress arising from the core symptoms of autism. Many adults with ASD seek psychological treatment in outpatient facilities in their communities that are not specifically geared toward individuals with ASD. However, few studies have looked at the effectiveness of standard psychotherapeutic care in adults with ASD. This study aimed to discover how individuals with ASD fare in psychotherapy within a college counseling setting, compared to their neurotypical peers. Clients with ASD (n = 76) or possible ASD (n = 91) were retrospectively identified from counseling center case notes. Data from the Outcome Questionnaire‐45 (OQ) were retrieved for each therapy session as a measure of client distress. Clients with ASD showed no difference in level of distress at intake compared to their neurotypical peers (n = 21,546), and improved about the same amount from pre‐ to post‐treatment. However, students with ASD stayed in treatment for significantly more sessions than neurotypical clients, and took significantly longer to achieve maximum improvement on OQ reports. Results are discussed with implications for university and other community based treatment settings. Autism Res 2017, 10: 2048–2055. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.Lay SummaryThis study aimed to discover how individuals with autism spectrum disorders (ASD) fare in psychotherapy within a university counseling setting, compared to their neurotypical peers. Clients with ASD showed no difference in level of distress at intake compared to their neurotypical peers, and improved about the same amount from pre‐ to post‐treatment. However, students with ASD stayed in treatment for significantly more sessions than neurotypical clients, and took significantly longer to achieve maximum improvement on Outcome Questionnaire‐45 reports.
Production and perception of emotional prosody by adults with autism spectrum disorder
Authors: Hubbard Daniel J. , Faso Daniel J. , Assmann Peter F. , Sasson Noah J. 
Published: August 2017

This study examined production and perception of affective prosody by adults with autism spectrum disorder (ASD). Previous research has reported increased pitch variability in talkers with ASD compared to typically developing (TD) controls in grammatical speaking tasks (e.g., comparing interrogative vs. declarative sentences), but it is unclear whether this pattern extends to emotional speech. In this study, speech recordings in five emotion contexts (angry, happy, interested, sad, and neutral) were obtained from 15 adult males with ASD and 15 controls (Experiment 1), and were later presented to 52 listeners (22 with ASD) who were asked to identify the emotion expressed and rate the level of naturalness of the emotion in each recording (Experiment 2). Compared to the TD group, talkers with ASD produced phrases with greater intensity, longer durations, and increased pitch range for all emotions except neutral, suggesting that their greater pitch variability was specific to emotional contexts. When asked to identify emotion from speech, both groups of listeners were more accurate at identifying the emotion context from speech produced by ASD speakers compared to TD speakers, but rated ASD emotional speech as sounding less natural. Collectively, these results reveal differences in emotional speech production in talkers with ASD that provide an acoustic basis for reported perceptions of oddness in the speech presentation of adults with ASD. Autism Res 2017, 10: 1991–2001. © 2017 International Society for Autism Research, Wiley Periodicals, Inc.Lay SummaryThis study examined emotional speech communication produced and perceived by adults with autism spectrum disorder (ASD) and typically‐developing (TD) controls. Compared to the TD group, talkers with ASD produced emotional phrases that were louder, longer, and more variable in pitch. Both ASD and TD listeners were more accurate at identifying emotion in speech produced by ASD speakers compared to TD speakers, but rated ASD emotional speech as sounding less natural.
Trends in indications, complications and outcomes for venous resection during pancreatoduodenectomy
Authors: Kleive D , Sahakyan M A , Berstad A E , Verbeke C S , Gladhaug I P , Edwin B , Fosby B , Line P-D , Labori K J 
Published: August 2017

Abstract

Background
Pancreatoduodenectomy with superior mesenteric–portal vein resection has become a common procedure in pancreatic surgery. The aim of this study was to compare standard pancreatoduodenectomy with pancreatoduodenectomy plus venous resection at a high-volume centre, and to examine trends in management and outcome over a decade for the latter procedure.

Methods
This retrospective observational study included all patients undergoing pancreatoduodenectomy with or without venous resection at Oslo University Hospital between January 2006 and December 2015. Trends were evaluated by assessing preoperative clinical and radiological characteristics, as well as perioperative outcomes in three time intervals (early, intermediate and late).

Results
A total of 784 patients had a pancreatoduodenectomy, of whom 127 (16·2 per cent) underwent venous resection. Venous resection resulted in a longer operating time (median 422 versus 312 min; P = 0·001) and greater estimated blood loss (EBL) (median 700 versus 500 ml; P = 0·004) than standard pancreatoduodenectomy. The rate of severe complications was significantly higher for pancreatoduodenectomy with venous resection (37·0 versus 26·3 per cent; P = 0·014). The overall burden of complications, evaluated using the Comprehensive Complication Index (CCI), did not differ (median score 8·7 versus 8·7; P = 0·175). Trends in venous resection over time showed a significant reduction in EBL (median 1050 versus 375 ml; P = 0·001) and duration of hospital stay (median 14 versus 9 days; P = 0·011) between the early and late periods. However, despite an improvement in the intermediate period, severe complication rates returned to baseline in the late period (18 of 43 versus 9 of 42 versus 20 of 42 patients in early, intermediate and late periods respectively; P = 0·032), as did CCI scores (median 20·9 versus 0 versus 20·9; P = 0·041).

Conclusion
Despite an initial improvement in severe complications for venous resection during pancreatoduodenectomy, this was not maintained over time. Every fourth patient with venous resection needed relaparotomy, most frequently for bleeding.
Particle–mesh coupling in the interaction of fluid and deformable bodies with screen space refraction rendering
Authors: Chan Ka‐Hou , Ke Wei , Im Sio‐Kei 
Published: August 2017

AbstractOn the basis of the smoothed particle hydrodynamics and finite element method (FEM) model, we propose a method integrating several improvements for the real‐time simulation of fluid interacting with deformable bodies. We improve the particle neighbor search in smoothed particle hydrodynamics, so that the predefined scene containers are no longer needed. This improvement can also be applied to the simulation of fluid interacting with other materials, such as rigid and soft bodies. We also propose a two‐way coupling method for fluid and deformable bodies, where the particle–mesh interaction is obtained by the ray‐traced collision detection method instead of the proxy/ghost particle generation. By using the forward ray‐tracing method for both velocity and position, we are able to calculate the coupling forces based on the conservation of momentum and kinetic energy in the particle–mesh interaction. We use the screen space fluid rendering for fluid, and on the basis of that, we introduce a screen space refraction rendering method to improve the refraction effect. We implement our method in NVIDIA CUDA and OptiX to make use of the full computational power of a graphics processing unit. The simulation results are analyzed and discussed to show the efficiency of our method.
Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert‐Butyl Isostere
Authors: Mukherjee Paramita , Pettersson Martin , Dutra Jason K. , Xie Longfei , am Ende Christopher W. 
Published: August 2017

AbstractThe synthesis of a new trifluoromethyl oxetane was developed using a Corey–Chaykovsky epoxidation/ring‐expansion reaction of trifluoromethyl ketones. The reaction was shown to proceed under mild conditions and displays a broad substrate scope. The trifluoromethyl oxetane was also evaluated as a tert‐butyl isostere in the context of the γ‐secretase modulator (GSM) program. We demonstrate that the trifluoromethyl oxetane‐containing GSM has decreased lipophilicity, improved lipophilic efficiency (LipE) and metabolic stability relative to the corresponding tert‐butyl GSM analogue, thus highlighting several benefits of trifluoromethyl oxetane as a more polar tert‐butyl isostere.
Tight temporal coupling between synaptic rewiring of olfactory glomeruli and the emergence of odor‐guided behavior in Xenopus tadpoles
Authors: Terni Beatrice , Pacciolla Paolo , Masanas Helena , Gorostiza Pau , Llobet Artur 
Published: August 2017

AbstractOlfactory sensory neurons (OSNs) are chemoreceptors that establish excitatory synapses within glomeruli of the olfactory bulb. OSNs undergo continuous turnover throughout life, causing the constant replacement of their synaptic contacts. Using Xenopus tadpoles as an experimental system to investigate rewiring of glomerular connectivity, we show that novel OSN synapses can transfer information immediately after formation, mediating olfactory‐guided behavior. Tadpoles recover the ability to detect amino acids 4 days after bilateral olfactory nerve transection. Restoration of olfactory‐guided behavior depends on the efficient reinsertion of OSNs to the olfactory bulb. Presynaptic terminals of incipient synaptic contacts generate calcium transients in response to odors, triggering long lasting depolarization of olfactory glomeruli. The functionality of reconnected terminals relies on well‐defined readily releasable and cytoplasmic vesicle pools. The continuous growth of non‐compartmentalized axonal processes provides a vesicle reservoir to nascent release sites, which contrasts to the gradual development of cytoplasmic vesicle pools in conventional excitatory synapses. The immediate availability of fully functional synapses upon formation supports an age‐independent contribution of OSNs to the generation of odor maps.
A Red‐Phosphorous‐Assisted Ball‐Milling Synthesis of Few‐Layered Ti3C2Tx (MXene) Nanodot Composite
Authors: Zhang Tianran , Jiang Xi , Li Guochun , Yao Qiaofeng , Lee Jim Yang 
Published: August 2017

AbstractLayered two‐dimensional (2D) early transition metal carbides (MXenes) are a new class of 2D materials with established activity for electrochemical energy conversion and storage. The use of MXenes is expected to increase by reducing their lateral size to the nanoscale. Herein, using Ti3C2Tx (T=O, OH, F) MXenes as an example, we show that μm‐sized MXenes can be reduced in size to ≈6 nm nanodots by ball‐milling with red phosphorous (P). It is remarkable almost all starting MXenes were converted to nanodots with this method. The Ti3C2Tx surface O groups interacted with P strongly and chemically to drive the nanodots formation. Ti3C2Tx nanodots (TNDs) with different sizes could also be obtained by ball‐milling Ti3C2Tx with other solid‐state elements such as carbon, sulfur and silicon. The as‐prepared TNDs and P composite was evaluated as a sodium‐ion battery anode material. A good sodiation capacity (≈600 mA h g−1) at 260 mA g−1 and good cycle stability for 150 cycles were shown.
Kinetic Parameters for the Selective Hydrogenation of Acetylene on GaPd2 and GaPd
Authors: Zimmermann René R. , Hahn Tobias , Reschetilowski Wladimir , Armbrüster Marc 
Published: August 2017

AbstractIntermetallic GaPd2 is a highly selective and stable catalyst for the semi‐hydrogenation of acetylene. Knowledge of the underlying reaction kinetics is essential to gain a deeper understanding of the selective hydrogenation on this catalytic material. To date, there has been no experimental kinetic data published for this reaction on a well‐defined intermetallic catalyst possessing isolated active sites. Kinetic measurements are performed at 140–200 °C, revealing an apparent activation energy of 29(2) kJ mol−1. GaPd2 is shown to be the first binary catalyst material, which shows a positive reaction order (0.89) with respect to acetylene at 200 °C. The influences on the extent of acetylene conversion, specific activity and selectivity to ethylene, ethane, and higher hydrocarbons are determined by a 24 factorial experiment following a design of experiments approach. Temperature and pressure have the strongest impact on these values. The results allow optimal operation for achieving high ethylene yields. A comparison of the reaction kinetics on GaPd2 with experimental results obtained for GaPd reveals different orders of reaction of H2 and C2H2 on the two compounds.
Catalytic Hydrodeoxygenation of High Carbon Furylmethanes to Renewable Jet‐fuel Ranged Alkanes over a Rhenium‐Modified Iridium Catalyst
Authors: Liu Sibao , Dutta Saikat , Zheng Weiqing , Gould Nicholas S. , Cheng Ziwei , Xu Bingjun , Saha Basudeb , Vlachos Dionisios G. 
Published: August 2017

AbstractInvited for this month′s cover is the group of Basudeb Saha and Dionisios G. Vlachos at the Catalysis Center for Energy Innovation (CCEI), University of Delaware. The image shows the use of renewable aviation fuels produced from C−C coupled biomass platforms. The Full Paper itself is available at 10.1002/cssc.201700863.
Dysregulation of wound healing mechanisms in diabetes and the importance of negative pressure wound therapy (NPWT)
Authors: Khamaisi Mogher , Balanson Sarit 
Published: August 2017

AbstractDiabetes is a serious disease with severe side effects and comorbidities. Diabetic foot with its chronic nonhealing ulcers, or diabetic foot ulcers, as they are commonly called, can be devastating, even leading to amputation. Many therapies exist to assist and improve wound healing. One exciting discovery is the use of negative pressure wound therapy (NPWT) as an adjunct to standard treatment. Few studies have substantively explored the molecular mechanisms of NPWT and why we see improved wound healing, a concept that demands more research. The following commentary summarizes the current literature regarding NPWT as well as some of the vast body of work that focuses on the physiologic mechanisms of wound healing in diabetics in general.
Invasive cane toads are unique in shape but overlap in ecological niche compared to Australian native frogs
Authors: Vidal‐García Marta , Keogh J. Scott 
Published: August 2017

SummaryInvasive species are an important issue worldwide but predicting invasiveness, and the underlying mechanisms that cause it, is difficult. There are several primary hypotheses to explain invasion success. Two main hypothesis based on niche spaces stand out as alternative, although not exclusive. The empty niche hypothesis states that invaders occupy a vacant niche space in the recipient community, and the niche competition hypothesis states that invaders overlap with native species in niche space. Studies on trait similarity/dissimilarity between the invader and native species can provide information on their niche overlap. Here, we use the highly invasive and well‐studied cane toad (Rhinella marina) to test these two hypotheses in Australia, and assess its degree of overlap with native species in several niche dimensions. We compare extensive morphological and environmental data of this successful invader to 235 species (97%) of native Australian frogs. Our study is the first to document the significant morphological differences between the invasive cane toad and a continent‐wide frog radiation: despite significant environmental overlap, cane toads were distinct in body size and shape from most Australian frog species, suggesting that in addition to their previously documented phenotypic plasticity and wide environmental and trophic niche breadth, their unique shape also may have contributed to their success as an invasive species in Australia. Thus, the invasive success of cane toads in Australia may be explained through them successfully colonizing an empty niche among Australian anurans. Our results support that the cane toad's distinct morphology may have played a unique role in the invasiveness of this species in Australia, which coupled with a broad environmental niche breadth, would have boosted their ability to expand their distribution across Australia. We also proposeRLLR(Relative limb length ratio) as a potentially useful measure of identifying morphological niche uniqueness and a potential measure of invasiveness potential in anuran amphibians.
Genetic wealth, population health: Major histocompatibility complex variation in captive and wild ring‐tailed lemurs (Lemur catta)
Authors: Grogan Kathleen E. , Sauther Michelle L. , Cuozzo Frank P. , Drea Christine M. 
Published: August 2017

AbstractAcross species, diversity at the major histocompatibility complex (MHC) is critical to individual disease resistance and, hence, to population health; however, MHC diversity can be reduced in small, fragmented, or isolated populations. Given the need for comparative studies of functional genetic diversity, we investigated whether MHC diversity differs between populations which are open, that is experiencing gene flow, versus populations which are closed, that is isolated from other populations. Using the endangered ring‐tailed lemur (Lemur catta) as a model, we compared two populations under long‐term study: a relatively “open,” wild population (n = 180) derived from Bezà Mahafaly Special Reserve, Madagascar (2003–2013) and a “closed,” captive population (n = 121) derived from the Duke Lemur Center (DLC, 1980–2013) and from the Indianapolis and Cincinnati Zoos (2012). For all animals, we assessed MHC‐DRB diversity and, across populations, we compared the number of unique MHC‐DRB alleles and their distributions. Wild individuals possessed more MHC‐DRB alleles than did captive individuals, and overall, the wild population had more unique MHC‐DRB alleles that were more evenly distributed than did the captive population. Despite management efforts to maintain or increase genetic diversity in the DLC population, MHC diversity remained static from 1980 to 2010. Since 2010, however, captive‐breeding efforts resulted in the MHC diversity of offspring increasing to a level commensurate with that found in wild individuals. Therefore, loss of genetic diversity in lemurs, owing to small founder populations or reduced gene flow, can be mitigated by managed breeding efforts. Quantifying MHC diversity within individuals and between populations is the necessary first step to identifying potential improvements to captive management and conservation plans.
Detection and Identification of Image Manipulation Based on Reversible Histogram Shift
Authors: OBARA YUKI , NIWA YUSUKE , WADA SHIGEO 
Published: August 2017

SUMMARYVerification of image manipulation for various alterations is an indispensable technology to protect original images. Conventional forgery detection methods using fingerprint are useful, since the original image is not required in detection process. However, manipulated local region can't be specified. Further, type of manipulation is not identified. In this article, a novel forgery identification method based on reversible histogram shift is proposed. Our method can detect partial and overall manipulation regions and identify manipulation type. Simulation results are shown to demonstrate the effectiveness of our method using various types of manipulated database images.
Review of Physiological Balance Sensing in an Unobtrusive Manner
Authors: OHASHI KEISHI , KUROIWA SHIGEKI , HIDESHIMA SHO , NAKANISHI TAKUYA , OSAKA TETSUYA 
Published: August 2017

SUMMARYThe concept of unobtrusive physiological balance sensing system implementing biosensors is discussed. Biosensors connected with a data system are expected to play a significant role when we extend the sensing objects from body to mind and spirit. Here, we describe the unobtrusive monitoring system using field effect transistor–type sensors and wireless communication devices. Substances subject to the survey of our research will include small ions, immunoglobulins, and hormones.
Power in Sustainability Transitions: Analysing power and (dis)empowerment in transformative change towards sustainability
Authors: Avelino Flor 
Published: August 2017

AbstractThis paper conceptualizes power and empowerment in the context of sustainability transitions and transition governance. The field of transition studies has been critically interrogated for undermining the role of power, which has inspired various endeavours to theorize power and agency in transitions. This paper presents the POwer‐IN‐Transition framework (POINT), which is developed as a conceptual framework to analyse power and (dis)empowerment in transformative social change, integrating transition concepts and multiple power and empowerment theories. The first section introduces transitions studies and discusses its state‐of‐the‐art regarding power. This is followed by a typology of power relations and different types of power (reinforcive, innovative, transformative). These notions are then used to reframe transition concepts, in particular the multi‐level perspective, in terms of power dynamics. The critical challenges of (dis)empowerment and unintended power implications of discourses on and policies for ‘sustainability transitions’ are discussed. The paper concludes with a synthesis of the arguments and challenges for future research. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
Maintenance of CD8+ memory T lymphocytes in the spleen but not in the bone marrow is dependent on proliferation
Authors: Siracusa Francesco , Alp Özen Sercan , Maschmeyer Patrick , McGrath Mairi , Mashreghi Mir‐Farzin , Hojyo Shintaro , Chang Hyun‐Dong , Tokoyoda Koji , Radbruch Andreas 
Published: August 2017

AbstractIt is current belief that numbers of CD8+ memory T lymphocytes in the memory phase of an immune response are maintained by homeostatic proliferation. Here, we compare the proliferation of CD8+ memory T lymphocytes, generated by natural infections and by intentional immunization, in spleen and bone marrow (BM). Fifty percent of CD8+ memory T lymphocytes in the spleen are eliminated by cyclophosphamide within 14 days, indicating that numbers of at least 50% of splenic CD8+ memory T lymphocytes are maintained by proliferation. The numbers of CD8+ memory T lymphocytes in the BM, however, were not affected by cyclophosphamide. This stability was independent of circulating CD8+ memory T cells, blocked by FTY720, showing that BM is a privileged site for the maintenance of memory T lymphocytes, as resident cells, resting in terms of proliferation.