bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Reliability for the Electrical Industries Company in Diyala using Modified Extension Weibull Distribution (An Application and Simulation study)
Authors: Mohamed Reda* Khansaa , Hassan AL- Kanani Lden 
Published: October 2024

In this paper defining modified extension Weibull distribution, reliability function and hazerd function, we explain the maximum likelihood method under type one censoring sample. The censored samples play an important role in reliability analysis .In this paper we estimate and derived modified extension Weibull distribution whith three parameters under the censored samples type one by maximum likelihood estimation method depend on Newton-Raphson method. Then we applied simulation procedure using Monte-Carlo technique to estimate reliability function under different samples sizes and various initial values for the parameters for all estimated parameters of modified extension Weibull model by used MATLAB program. Finally we find the probability density function f(t), reliability function R(t),and hazard function h(t) for real data which get it from (Diyala province Company) is one of the formations of the Ministry of Industry and Minerals.

Paper type: Research paper
KEGIATAN GEBYAR TAHUN BARU HIJRIAH DI MASJID NURUL YAQIN TEMBILAHAN
Authors: Erdawati Sri , Arivaie Rahman  
Published: October 2024

Kegiatan Gebyar Tahun Baru Hijriah sudah menjadi tradisi di Masjid Nurul Yaqin Tembilahan. Kegiatan ini diadakan untuk memperingati Hijrahnya nabi Muhammad dari Mekkah Ke Madinah, peristiwa inilah dijadikan titik awal pembentukan kalender Islam. Ada banyak kegiatan yang dilakukan di Masjid Nurul Yaqin dalam momentum ini, di antaranya adalah mengadakan lomba hafalan surah-surah pendek pilihan, lomba adzan, lomba shalawat nariyah, dan lomba rangking satu. Dengan diadakannya kegiatan ini anak-anak termotivasi untuk belajar Islam,serta mampu mengembangkan minat dan bakat. Kegiatan ini mendapat respon yang sangat positif, terlihat dari banyaknya peserta yang mendaftar berjumlah 60 orang peserta dengan rincian: 34 orang peserta lomba hafalan surah pendek pilihan, 12 orang peserta lomba adzan, dan 14 orang peserta lomba shalawat nariyah, ramainya pengunjung yang hadir, dan dukungan para donator. Sehinggga, kegiatan ini berlangsung dengan mudah, lancar, dan sukses.
IMPLEMENTASI ALGORITMA FP-GROWTH UNTUK REKOMENDASI PEMINJAMAN BUKU DI PERPUSTAKAAN UNIVERSITAS DARUSSALAM GONTOR
Authors: Muhammad Ridwan  , Aziz Musthafa  , Dihin Muriyatmoko  
Published: October 2024

Perpustakaan merupakan pusat dari peradaban keilmuan dalam dunia Pendidikan dan akademik dan juga sebagai pusat informasi. Dan perpustakaan di Universitas Darussalam Gontor merupakan pusat dari jantungnya Universitas. Di dalam mengelola literatur peminjaman buku, perpustakaan terkadang di hadapi dengan masalah rekomendasi buku dan koleksi kepada pemustaka. Data semakin lama akan bertambah semakin banyak. degan demikian adanya perkembang yang sangat pesat dengan demikian kita memanfatkan teknologi yang di mana dari data yang terbengkalai dapat kiata kelolah menjadi suatu analisis rekomendasi judul buku. Penelitian ini bertujuan memudahkan mahasiswa mencapai dalam mencari rekomendasi buku yang cocok untuk di pinjam. Dengan menggunakan metode Fp-Growth, penelitian melibatkan pengumpulan data, Data yang di gunakan untuk penelitian ini ada data dari awal sampai 2022 yang di mana data Loan History memiliki 4851 dan data Loan Bay Class memiliki 2127. Dan dalam penelitian ini menggunakanseluruh data untuk di lakukan testing, dan adapun tools yang akan di gunakan dalam pengelolahan dari data yang kita ambil adalah tools RapidMiner, dengan artribut yang akan mencakupi Fp-growth dan Association Rules. Berdasarkan analisis dari penelitian ini semua aturan yang akan di hasilkan memiliki nilai 91% Loan History dan 96% dari data Loan Bay class sehingga data dapat di gunakan dalam untuk refrensi rekomendasi dalam peminjaman buku.
Kata kunci: UNIDA, Perpustakaan, Data Mining, Fp-Growth
PEMBERDAYAAN MASYARAKAT NON-PRODUKTIF DESA BANTENGAN MELALUI PELATIHAN PEMBUATAN MINYAK GORENG BERBAHAN DASAR DEDAK PADI (RICE BRAN) UNTUK MENINGKATKAN EKONOMI
Authors: Dyan Hatining Ayu Sudarni  , Nur Ihda Farikhatin Nisa  , Yudha Adi Kusuma  
Published: October 2024

Mahalnya minyak goreng saat ini menyebabkan banyak ibu rumah tangga rela mengantri untuk membeli, sampai sampai waktu seharian habis untuk mengantri minyak. Selain mahal minyak goreng ini tergolong langka di pasaran oleh sebab itu, muncul ide pembuatan minyak goreng dengan bahan dasar selain kelapa sawit dan kelapa. Salah satu limbah yang melimpah dan banyak di temui adalah limbah padat dedak padi (bekatul). Melimpahnya jumlah limbah padat penyosohan padi yaitu dedak di Indonesia berpotensi untuk dijadikan minyak pangan. Minyak pangan berbasis dedak padi dapat djadikan sebagai alternatif pengganti minyak pangan berbasis kelapa saawit, karena minyak dedak padi mengandung senyawa fitokimia dalam jumlah tinggi, antioksidan dan beberapa jenis lemak. Minyak dedak yang dihasilkan oleh ibu ibu di desa bantengan ini berkolaborasi dengan mahasiswa Teknik Kimia UNIPMA. Dimana rendemen minyak 16%, mengandung antioksidan yang tinggi (tocorefol, tocotrienol dan oryzanol). Hasil ini termasuk dikategorikan baik. Hasil minyak dedak yang dihasillkan masih digunakan untuk perorangan atau kelompok ibu ibu PKK di Desa Bantengan sendiri. Hal ini dikarena masih banyak warga yang masih ragu dengan minyak yg telah dibuat karena belum melalui uji yang terstandarisasi sesuai BPOM. Pengembangan produk minyak deda sebagai food supplement dan minuman antioksida serta diversifikasi produk olahan padi dapat meningkatkan nilai tambah produk
Upaya Memberantas Buta Aksara Huruf Hijaiyah (Al-Qur’an) di Sungai Padi, Narathiwat, Thailand
Authors: Vauziah Rizka , Hasanah Siti Muawanatul 
Published: October 2024

Abstak
Al-Quran merupakan kitab suci bagi umat Islam, Al-Qur’an memiliki kedudukan yang sangat mulia. Kemampuan membaca Al-Quran adalah suatu keberkahan dan tanggung jawab bagi setiap Muslim. Idealnya, semua masyarakat Muslim bisa membaca dan menulis Al-Qur’an. Namun pada kenyataannya masih ada umat Islam di Sungai Padi, Ban, Air Batu, Narathiwat, Thailand yang masih mengalami buta aksara Al-Qur’an. Dalam rangka memberantas buta aksara Al-Qur’an, berbagai macam cara dilakukan agar mudah dan bisa dipelajari oleh setiap muslim yang belum bisa membaca kitab suci Al-Qur’an, yaitu dengan Membentuk program pengajaran Al-Qur’an dan dengan Metode Tahsin. Upaya-upaya yang dilakukan untuk menghadapi tantangan tersebut diantaranya ialah program pemberantasan buta huruf bagi masyarakat yang terlanjur memiliki tingkat pendidikan formal yang rendah. Oleh karena itu, salah satu langkah awal yang dilakukan yaitu dengan melaksanakan program intensif pemberantasan buta aksara huruf arab pada masyarakat khususnya ibu-ibu lanjut usia. Dengan metode Tahsin, metode ini megupayakan untuk memperbaiki bacaan Al-Qur’an agar sesuai dengan aturan tajwid dan memperindah bacaan dengan menggunakan nada ketika membaca ayat suci Al-Qur’an. Hasil dari pembentukan program pengajaran Al-Qur’an ini dengan metode Tahsin terbukti efisien diterapkan kepada ibu-ibu lanjut usia, metode ini terbukti efektif memudahkan peserta didik yang belum bisa membaca huruf hijaiyah mempelajari cara membaca Al-Quran.
Perbedaan Adekuasi Hemodialisis pada Pasien Akses AV Shunt dan AV Femoral
Authors: Pranowo Suko , Hartati Ida , Kasron Kasron 
Published: October 2024

Adequacy of hemodialysis is the adequacy of the number of hemodialysis processes which is characterized by patients feeling better and comfortable. Hemodialysis access can be done with an Arterio-Venous (AV) shunt will increase blood flow rapidly. Another access to get central venous access can use the femoral AV. The use of hemodialysis access can affect adequacy. The purpose of this study was to determine differences in the adequacy of hemodialysis in patients with AV shunt and AV Femoral access. This research uses quantitative research with comparative descriptive method. Time approach using cross sectional. A sample of 32 people were divided into 2 groups, namely the AV shunt access group and the AV femoral access group. The sampling technique used a purposive sampling technique in accordance with the inclusion and exclusion criteria. Data analysis used independent t-test. The average urea level in hemodialysis patients with AV shunt access was 74.72% and AV femoral access was 67.05%.There was a significant difference in the adequacy of hemodialysis in patients with AV shunt and AV femoral access (pv = 0.013). Cilacap General Hospital is advised to improve its services by opening an AV shunt installation facility and providing education to Chronic Renal Failure (CRF) patients so that patients are motivated to install an AV shunt.
Association between mitral annulus calcification and severity of coronary artery disease assessed by SYNTAX score in patients presented with acute coronary syndrome
Authors: Esmailpour Afsaneh , Nematollahi Soroush , Hali Reza , Sadeghian Mohammad , Nayebirad Sepehr , Vakili Ahmad 
Published: October 2024

ObjectivesMitral annulus calcification (MAC) has been linked to cardiovascular disease severity, but its relationship with the SYNTAX score (SS) in acute coronary syndrome (ACS) patients remains unclear. This study aimed to investigate the association between MAC and SS in ACS patients to explore the role of MAC in predicting cardiovascular disease severity.MethodsWe conducted a cross-sectional study of 233 ACS patients at Tehran Heart Center, Tehran, Iran, from December 2021 to August 2022. Patients with prior coronary artery disease (CAD) were excluded. Demographic data, risk factors, and medical history were extracted from clinical files. SS was determined using coronary angiography, and MAC was assessed via two-dimensional transthoracic echocardiography.ResultsThe study population had a mean age of 58.79 years, with 74.7% male. MAC was present in 24.9% of participants, and 57% of those with MAC had an SS above 23. Univariate analysis revealed a significant association between MAC and higher SSs (odds ratio: 1.84, 95% CI: 1.02–3.39; P = 0.046). However, multivariable analysis showed that only left ventricular ejection fraction (LVEF) was independently associated with SS (odds ratio: 0.94, 95% CI: 0.89–0.99; P = 0.015).ConclusionWhile MAC was initially associated with higher SSs in ACS patients, only LVEF emerged as an independent predictor in the multivariable analysis. Although MAC may not be independently associated with SS, it may serve as a useful echocardiographic indicator of more severe CAD in ACS.
Risk and predictors of severe hyperkalemia after total parathyroidectomy without auto-transplantation in patients with secondary hyperparathyroidism
Authors: He Chenchen , Li Longfei , Pan Junhao , Cheng Guangming , Wang Chunhui , Tang Yufu 
Published: October 2024

ObjectiveTo identify the risk factors of postoperative severe hyperkalemia after total parathyroidectomy (TPTX) without auto-transplantation in patients with secondary hyperparathyroidism (SHPT).MethodsData on 406 consecutive patients who underwent TPTX without auto-transplantation for secondary hyperparathyroidism at the General Hospital of Northern Theater Command between January 2013 and January 2023, were prospectively collected. Then, patients were divided into the training set (n=203) and the validation set (n=203) in a ratio of 1:1 by timeline. The patients were divided into severe hyperkalemia group and non-hyperkalemia group according to the postoperative serum kalium level &gt;6.0 mmol/L with ECG changes or serum kalium level ≥6.5 mmol/L. Univariate and multivariate logistic regression analyses were used to evaluate the possible risk factors associated with postoperative severe hyperkalemia after TPTX. The predictive performance was evaluated with receiver operating characteristic (ROC) curves with the areas under the ROC curve (AUC) and calibration curve. Decision curve and clinical impact curve analyses were used to validate the clinical application of the value.ResultsThe incidence of postoperative severe hyperkalemia was 15.5% in all patients, 17.2% and 13.8% in the training and validation cohorts, respectively. The risk factors associated with postoperative severe hyperkalemia was higher preoperative kalium level. The optimal cut-off value for preoperative serum kalium level was 5.0mmol/L according to the ROC curve. The area under the curve (AUC) achieved good concordance indexes of 0.845 (95%CI, 0.776-0.914) in the training cohort. The sensitivities were 0.829 (95%CI: 0.663-0.934) and 0.857 (95%CI: 0.673-0.960) in the training and validation cohorts, respectively. The specificities were 0.798 (95%CI: 0.729-0.856) and 0.720 (95%CI:0.647-0.785) in the training and validation cohorts, respectively. Calibration curve exhibited a good consistency between actual observations and predicted severe hyperkalemia in the training and validation cohorts.ConclusionsOur study found that the preoperative kalium levels is only a risk factor for postoperative severe hyperkalemia in patients undergoing TPTX for secondary hyperparathyroidism. The threshold for preoperative serum kalium levels is 5.0mmol/L that can serve as a useful indicator for identifying patients with severe hyperkalemia after surgery. These results provide valuable suggestion for clinical practice.
Opioid−free anesthesia attenuates perioperative immunosuppression by regulating macrophages polarization in gastric cancer patients treated with neoadjuvant PD-1 inhibitor
Authors: Liu Wenjian , Ou Chaopeng , Xue Ruifeng , Yang Xiaohua , Ye Yaqi , Wang Xudong , Xie Jingdun 
Published: October 2024

BackgroundOpioid anesthesia can modulate the impaired immune response and opioid-sparing anesthesia may preserve immune functions. This study was performed to assess the effects of opioid-free anesthesia (OFA) and opioid-based anesthesia (OA) on perioperative macrophages differentiation, cytokine changes, and perioperative complications in locally advanced GC (LAGC) patients.MethodsWe used quality of recovery-15 (QoR-15) questionnaire scores and visual analog scale (VAS) scores to compare postoperative quality of recovery and pain level. In addition, the adverse reactions of patients in the two groups were compared. The perioperative serum level of inflammatory cytokines and the ratio of macrophage subtypes were detected.ResultsThe OFA group had significantly longer extubation time and PACU stay, whereas the OA group had significantly higher rate of hypotension, higher doses of norepinephrine, higher PONV and dizziness rate, and delayed flatus passage time. The QoR-15 score on postoperative 24 h was significantly higher in OFA group than in OA group. At the end of or after the surgery, the OFA group had higher levels of interleukin (IL)-12, IL-1β, tumor necrosis factor (TNF)-α, CD68+CD163− macrophage rate, but lower levels of IL-10, transforming growth factor (TGF)-β, and CD68+CD163+ macrophage rate, indicating OFA attenuated perioperative immunosuppression by diminishing M2 and promoting M1 macrophage polarization. And the reversal tendency is more obvious in LAGC patients with neoadjuvant PD-1 inhibitor.ConclusionsThe OFA may attenuate perioperative immunosuppression by diminishing M2 and promoting M1 macrophage polarization in LAGC patients with neoadjuvant PD-1 inhibitor.Clinical trial registrationhttp://gcpgl.sysucc.org.cn, identifier 2022-FXY-001.
Tertiary lymphoid structure-related score as a predictor for survival prognosis and immunotherapy response in head and neck squamous cell carcinoma
Authors: Wu Fan , Cao Haotian , Ren Siqi , Wu Jiaying , Liu Xin , Li Qunxing , Xu Qiuping , Chen Jiali , Wang Ruixin , Chen Suling , Kuang Shijia , Xia Binbin , Li Yanyan , Wang Liansheng , Li Jintao , Li Bowen , Li Jinsong , Lan Tianjun 
Published: October 2024

BackgroundSubstantial studies reveal that tertiary lymphoid structure (TLS) correlate with prognosis and immunotherapy response in various types of cancers. However, the predictive value of TLS, the specific immune cell subtype within TLS and their anti-tumor mechanisms remain unclear.MethodsBased on 23 TLS-related genes (TLSRGs), we utilized bioinformatics methods to construct a scoring system, named TLSscore. By integrating RNA and single-cell sequencing data, we assessed the utility of TLSscore in head and neck squamous cell carcinoma (HNSCC). Flow cytometric sorting was used to isolate specific T cells subtypes, in vivo and in vitro experiments were conducted to demonstrate its anti-tumor effects.ResultsThe TLSscore model was constructed and specific TLSscore-genes were found to consistently align with the spatial location of TLS. TLSscore has proven to be a robust predictive model for predicting survival prognosis, immune cell infiltration, somatic mutation and immunotherapy response. Notably, a specific PD1+CXCL13+CD8+T cell subtype was identified within TLS. Both in vivo and in vitro experiments demonstrated that PD1+CXCL13+CD8+T cell might represent a functional cell subtype exerting anti-tumor effects during the process of immune surveillance.ConclusionsOur study presents a predictive model for TLS, which can evaluate its presence and predicts survival prognosis and immunotherapy response in HNSSC patients. Additionally, we identify a specific subtype of T cells that might elucidate the mechanism of TLS function in anti-tumor activities. This T cell subtype holds the potential to be a prognostic marker and a target for adoptive cell therapy (ACT) in the future.
Sex differences and testosterone interfere with the structure of the gut microbiota through the bile acid signaling pathway
Authors: Duan Xueqing , Nie Yinli , Xie Xin , Zhang Qi , Zhu Chen , Zhu Han , Chen Rui , Xu Jun , Zhang Jinqiang , Yang Changfu , Yu Qi , Cai Kun , Wang Yong , Tian Weiyi 
Published: October 2024

BackgroundThe gut microbiome has a significant impact on human wellness, contributing to the emergence and progression of a range of health issues including inflammatory and autoimmune conditions, metabolic disorders, cardiovascular problems, and psychiatric disorders. Notably, clinical observations have revealed that these illnesses can display differences in incidence and presentation between genders. The present study aimed to evaluate whether the composition of gut microbiota is associated with sex-specific differences and to elucidate the mechanism.Methods16S-rRNA-sequencing technology, hormone analysis, gut microbiota transplantation, gonadectomy, and hormone treatment were employed to investigate the correlation between the gut microbiome and sex or sex hormones. Meanwhile, genes and proteins involved bile acid signaling pathway were analyzed both in the liver and ileum tissues.ResultsThe composition and diversity of the microbiota from the jejunum and feces and the level of sex hormones in the serum differed between the sexes in young and middle-aged Sprague Dawley (SD) rats. However, no similar phenomenon was found in geriatric rats. Interestingly, whether in young, middle-aged, or old rats, the composition of the microbiota and bacterial diversity differed between the jejunum and feces in rats. Gut microbiota transplantation, gonadectomy, and hormone replacement also suggested that hormones, particularly testosterone (T), influenced the composition of the gut microbiota in rats. Meanwhile, the mRNA and protein level of genes involved bile acid signaling pathway (specifically SHP, FXR, CYP7A1, and ASBT) exhibited gender-specific differences, and T may play a significant role in mediating the expression of this pathway.ConclusionSex-specific differences in the structure of the gut microbiota are mediated by T through the bile acid signaling pathway, pointing to potential targets for disease prevention and management techniques by indicating that sex differences and T levels may alter the composition of the gut microbiota via the bile acid signaling pathway.
Ecological shifts in soil microbiota and root rot disease progress during ginseng monoculture
Authors: Cho Gyeongjun , Kim Da-Ran , Kwak Youn-Sig 
Published: October 2024

IntroductionThe phenomenon in which the damage of plant diseases is suppressed by continuous cropping is defined as “suppressiveness” and the development of suppressive soils and key beneficial microorganisms have been identified through various previous studies. However, no studies have been conducted on microbial communities related to disease occurrence before the initial occurrence of diseases in crop monoculture.MethodsWe aimed to investigate the ecological modifications of pathogen population density in soil, disease occurrence rate, and microbiota community shifting during ginseng monoculture to better understand the tripartite social relationships in the monoculture system. To achieve the study’s objectives, a long-term monoculture of ginseng was established. The microbial diversity and community structure were analyzed using high-throughput sequencing, and the pathogen population density and disease occurrence rate were determined using qPCR and observation.Results and discussionThe results showed that the initial rhizosphere bacterial community of ginseng had already collapsed before the development of the root rot disease. The study also identified the crucial role of soil-borne pathogens in causing disease and the loss of initial keystone taxa populations in the early stages of monoculture. Our study revealed a novel aspect of soil microbiota dynamics during ginseng monoculture, with seven distinct microbes (Beijerinckiaceae, Comamonadaceae, Devosiaceae, Rhizobiaceae, Sphingobacteriaceae, Sphingomonadaceae, and Xanthomonadaceae) participating in soil nitrogen metabolism as an ‘initial community’ that regulates root rot disease through nutritional competition. The findings contribute to ecological research on disease-suppressiveness soil, disease management, and sustainable agriculture.