bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of γ-Irradiation on the Chemisorption and Catalytic Activity of Ni/Al2O3 and Co/Al2O3 Systems
Authors: Youssef A.M. , El-Nabarawy Th. , Badr G.E. 
Published: January 2017

The textural properties of non-irradiated and γ-irradiated Ni/Al2O3 and Co/Al2O3 systems with different chemical compositions were determined from the adsorption of nitrogen at 77 K. Chemisorption of hydrogen at 320 K and hydrogenation of benzene at 400 K were studied on the reduced catalysts. The surface areas of γ-irradiated catalysts are higher than those of their non-irradiated equivalents. γ-Irradiation also increases the hydrogen uptake, the metallic surface area and the percentage dispersion of the metal on the support. The hydrogenation activity also increases upon irradiation with γ-rays. All these changes are more pronounced in catalysts with a high metal loading.
A Comparison of Varicography and Descending Phlebography in Clinically Suspected Recurrent Groin and Upper Thigh Varicose Veins
Authors: Thomas M. Lea , Mahraj R.P.M. 
Published: January 2017

Seventeen legs in 11 patients with recurrent groin or upper thigh varices were examined by both varicography and descending phlebography. In five legs recurrences were shown by both techniques, in 10 by varicography alone, and in three by descending phlebography alone. It is suggested that both varicography and descending phlebography may be necessary to evaluate recurrent varicose veins following surgery.
Factors associated with perceived participation three months after being discharged from a tertiary hospital
Authors: Chen Xuemei , He Yanan , Meng Xianmei , Zhou Lanshu 
Published: January 2017

Objectives: To describe how first-stroke survivors perceive their participation and the problems with such participation in life and to determine the factors associated with perceived participation at three months after hospital discharge. Design: A cross-sectional study. Setting: Patients were recruited from a tertiary hospital in Shanghai, China and they were followed up in their homes. Subjects: Two hundred and fifty-seven first-stroke survivors discharged for three months participated in this study. Measures: The Chinese version of the Impact on Participation and Autonomy questionnaire, Barthel Index, Chinese Stroke Scale, Hospital Anxiety and Depression Scale and Social Support Rating Scale. Results: One hundred thirty-four (52.1%) and 147 (57.2%) participants perceived their participation as poor to very poor in the domains of family role and autonomy outdoors, respectively. Conversely, 208 (80.9%) and 228 (88.7%) participants perceived their participation to be fair to good in the domains of social relations and autonomy indoors, respectively. The ability to perform activities of daily life was the strongest correlate of participation in the domains of autonomy indoors, family role, and autonomy outdoors, whereas anxiety was the strongest correlate of participation in the domain of social relations. Conclusions: Activities of daily living were significantly associated with perceived participation in almost all domains. In contrast, anxiety was an important factor in predicting participation in the domain of social relations. These findings suggest the need to explore different strategies of promoting participation for each domain.
Additive value of “otosclerosis-weighted” images for the CT diagnosis of fenestral otosclerosis
Authors: Yamashita Koji , Hiwatashi Akio , Togao Osamu , Kondo Masatoshi , Kikuchi Kazufumi , Inoguchi Takashi , Maehara Junki , Kyuragi Yusuke , Honda Hiroshi 
Published: January 2017

Background Otosclerotic foci are usually seen as minute low-density lesions and this may be attributed to relatively low sensitivity on visual assessment using computed tomography (CT). Otosclerotic foci can be detected by using the accurate region of interest (ROI) setting, while small ROI settings by less-experienced radiologists may result in false negative findings. Purpose To evaluate the diagnostic ability of our proposed method (“otosclerosis-weighted” imaging [OWI]), which is based on reversing the density, compared with conventional CT (CCT) imaging alone. Material and Methods Temporal bone CTs of consecutive patients with otosclerosis were analyzed. Gender- and age-matched control participants were also included. All CT images were obtained using a 64-detector row scanner. OWI was obtained by extracting the temporal bone region using the threshold technique and reversing the density (black to white). Four independent radiologists took part in two reading sessions. In the first session, the observers read only CCT imaging. In the second session, they read OWI along with the CCT imaging. Sensitivity was assessed for the four readers. Results Thirty temporal bones of 25 patients with otosclerosis (3 men, 22 women; mean age, 53.9 ± 9.0 years) and 30 temporal bones of 30 control participants (4 men, 26 women; mean age, 44.0 ± 16.2 years) were included. For all observers, reading with a combination of the two methods was associated with a higher sensitivity (63.3–80.0%) than with conventional CT images alone (30.0–60.0%; P < 0.05, each). Conclusion Application of our proposed method based on threshold value may help detect foci of fenestral otosclerosis.
Luteal-phase protocol in poor ovarian response: a comparative study with an antagonist protocol
Authors: Wu Yan , Zhao Fu-Chun , Sun Yong , Liu Pei-Shu 
Published: January 2017

Objective This retrospective study compared the effect of the luteal phase ovarian stimulation protocol (LP group) with the gonadotrophin-releasing hormone (GnRH) antagonist protocol (AN group) in women with poor ovarian responses. Methods Ovarian stimulation was initiated with 225 IU of human gonadotrophin (hMG) daily. When the dominant follicle diameter exceeded 13 mm, 0.25 mg of a GnRH antagonist was used daily until human chorionic gonadotrophin (HCG) administration in the AN group. A GnRH antagonist was not used in the LP group. Ovulation was induced with HCG for all patients when at least one follicle reached a diameter of 16 mm or one dominant follicle reached 18 mm. The highest quality embryos were transferred or cryopreserved for later transfer. Results From January 2013 to December 2015, 274 women with poor ovarian response were included. A total of 108 patients underwent the luteal phase ovarian stimulation protocol while 166 patients underwent the GnRH antagonist protocol. hMG was used for more total days in the LP group was than in the AN group. Oestradiol levels on the day of HCG administration in the LP group were significantly lower than those in the AN group. The mean number of oocytes retrieved in the LP and AN groups was 3.5 ± 2.5 and 3.5 ± 2.9, respectively. The mean number of embryos of the highest quality was 1.7 ± 1.2 and 1.7 ± 1.5, respectively. The clinical pregnancy and implantation rates in the LP and AN groups were 26.2% (22/84) and 25% (29/116), and 15.5% (24/155) and 16.3% (35/215), respectively. Conclusions The luteal phase ovarian stimulation protocol can be applied in women with poor ovarian response and attain comparable clinical pregnancy and implantation rates to those of the GnRH antagonist protocol.
The Interactions of Ticlopidine and Aspirin in Normal Subjects
Authors: Thebault Jean-J , Blatrix Charles E , Blanchard Jean F , Panak Edouard A 
Published: January 2017

This trial was performed on 24 healthy volunteers in order to study the possible interactions between aspirin and ticlopidine. The results confirm the inhibitory activity of aspirin on collagen-induced aggregation and that of ticlopidine on ADP-induced aggregation. If aspirin does not modify the inhibitory effect of ticlopidine on ADP-induced aggregation, ticlopidine on the other hand potentiates the effect of aspirin on collagen-induced aggregation.
The Effect of Fenoprofen Calcium (Nalfon) on Levels of Rheumatoid Factor in Patients with Rheumatoid Arthritis
Authors: Himes Joan E , Duff Ivan F 
Published: January 2017

In 88.9% of a group of 18 patients with rheumatoid arthritis participating in an open-label study with fenoprofen calcium (Nalfon), there was observed a mean litre decrease in level of rheumatoid factor as compared to baseline levels. In follow-up, three months to one year later, a uniform litre increase above the mean level of the study period had occurred. In all cases the titre returned to baseline levels or higher.
Tinidazole and Metronidazole in the Treatment of Amoebic Liver Abscess
Authors: Mathur S N , Itigi Anantesh , Krishnaveni  , Rai Vimal 
Published: January 2017

Tinidazole, a new drug effective against E histolytica, was studied in patients with amoebic liver abscess proved by aspiration of pus. A preliminary open evaluation in fourteen patients provided a cure in all cases. A subsequent comparative study against metronidazole in another twenty-two patients led to a cure in all eleven patients treated with tinidazole and in ten out of eleven patients treated with metronidazole. The response was faster in patients treated with tinidazole. Tinidazole was totally free from side-effects. Tinidazole is a noteworthy addition to anti-amoebic therapy.
Experience with Etomidate: A Hypnotic for Induction of Anaesthesia
Authors: Urdinovic S , Karoussos K 
Published: January 2017

The authors report on their experience with combined etomidate anaesthesia in 500 varied surgical procedures including thoracic and neurosurgery. Specific indications for the new short-term hypnotic etomidate are dealt with, including anaesthesia in poor-risk patients, conditions of shock, spastic bronchitis, and bronchial asthma. When used for the induction of neuroleptic analgesia, etomidate offers certain benefits. Since it induces few side-effects, it is suggested that this preparation is the drug of choice for ambulatory anaesthesia, Caesarean section, etc.
Double Acting Betamethasone (Celestone Chronodose®) in the Treatment of Supraspinatus Tendinitis
Authors: Valtonen Erkki J 
Published: January 2017

The author reports the results of a placebo controlled trial of Celestone Chronodose® in the treatment of supraspinatus tendinitis involving a total of 180 patients. The results after local injection and deep gluteal injection are also compared.
An Open Study of Mupirocin in Libyan Patients with Skin Infections
Authors: Ferghani N El 
Published: January 2017

In an open study in Libya 48 patients suffering from skin infections, usually caused by staphylococci and streptococci, were treated with a new topical antibiotic, mupirocin, applied three times daily for 7 days. By day 7 of treatment 93.5% of patients were asymptomatic and were considered cured, and 100% were considered cured 1 week later. In total, 50 bacterial strains were isolated, of which, 86% were staphylococci and 14% were streptococci. Neither adverse events nor cutaneous reactions were reported. Mupirocin 2% ointment proved to be effective and safe in the treatment of primary and secondary skin infections. Quarante-huit patients souffrant d'infections de la peau et des tissus mous, causées habituellement par des Staphylocoques et des Streptocoques furent traités par un nouvel antibiotique topique, la mupirocine, appliquée trois fois par jour pendant 7 jours, dans une étude ouverte réalisée en Lybie. Au jour 7, le taux de réponse au traitement était de 93.5% pour atteindre 100% une semaine plus tard. Au total, 50 souches bactériennes furent isolées, uniquement des staphylocoques (86%) et streptocoques (14%); aucun effet secondaire au traitement ne fut rapporté. La mupirocine, pommade à 2%, s'est montrée eficace et sûre dans le traitement des infections primaires et secondaires de la peau et des tissus mous.
Mizolastine is Effective and Well Tolerated in Long-Term Treatment of Perennial Allergic Rhinoconjunctivitis
Authors: Scadding GK , Tasman AJ , Murrieta-Aguttes M , Bachert C ,   And The Riperex Study Group
Published: January 2017

The aim of this study was to determine the long-term efficacy and safety of mizolastine, a new second-generation antihistamine with European approval, in the treatment of perennial allergic rhinoconjunctivitis. In this study, 141 patients were treated with once-daily mizolastine 10 mg or 15 mg in a 5-month open-label extension of a 1-month double-blind, placebo-controlled trial, which assessed once-daily mizolastine 10 mg. Mizolastine significantly reduced the nasal subscore (sneezing, rhinorrhoea, itch; end-baseline ± SD, −2.5 ± 6.3), nasal obstruction (−1.2 ± 2.6) and rhinoscopy scores (−1.3 ± 2.6), and improved ocular and total nasal scores after 6 months' treatment. Improvement was maintained for the duration of the study with no loss of drug efficacy. Adverse effects were mild with no specific effects associated with prolonged use. These results clearly demonstrate that mizolastine is effective and well tolerated in the long-term treatment of perennial allergic rhinoconjunctivitis. The significant clinical improvement in nasal blockade may reflect mizolastine's histamine/5-lipoxygenase dual inhibition. El objectivo del estudio fue de evaluar en pacientes con rinoconjuntivitis alérgica perenne la eficacia y la seguridad de un nuevo antihistamínico de segunda generación licenciado a nivel Europeo. Este estudio fue la prolongación de un estudio con mizolastine 10 mg, doble ciego, controlado con placebo de un mes de duración en el cual se incluyeron 257 pacientes. 141 de estos continuaron en esta fase de extensión que duró 5 meses. Mizolastine redujo significativamente las subpuntuaciones nasales: estornudos, rinorrea, picor; final–basal ± ds, −2.5 ± 6.3, la obstrucción nasal (−1.2 ± 2.6) y las puntuaciones rinoscópicas (−1.3 ± 2.6). El control fue mantenido durante toda la duración del estudio (6 meses) sin pérdida de eficacia. Los efectos secundarios fueron ligeros y no específicos de un tratamiento prolongado. Estos resultados demuestran claramente que mizolastine es eficaz y bien tolerada en el tratamiento prolongado de la rinoconjuntivitis alérgica perenne. El control, clínicamente significativo, de la obstrucción nasal puede ser el reflejo de la doble actividad farmacológica de la mizolastine, acción sobre la histamine y la 5-lipooxigenasa.
Etiologic Studies of Old Dog Encephalitis
Authors: Lincoln S. D. , Gorham J. R. , Ott R. L. , Hegreberg G. A. 
Published: January 2017

In 2 cases of old dog encephalitis (ODE), viral antigen to canine distemper was demonstrated in frozen brain tissue by means of the direct FA test. The distemper viral antigen was most abundant in cells of the gray matter of the cerebral cortex, thalamus, mesencephalon, and medulla. Also, in the 1 dog in which serum was available, there was a significantly elevated serum antibody titer to the distemper agent. Attempts to isolate a viral agent in tissue culture or to transmit disease to distemper-susceptible ferrets or distemper-immune adult dogs were unsuccessful. Results of this study indicate that the virus of distemper play a role in the pathogenesis of ODE. Also, the progressive disease with inflammatory reaction suggests that a slow viral infection rather than a totally masked or latent virus be involved.
Feline Insular Amyloid: Histochemical Distinction from Secondary Systemic Amyloid
Authors: Yano B. L. , Johnson K. H. , Hayden D. W. 
Published: January 2017

Amyloid in islets of Langerhans from 48 domestic cats, one human, one non-human primate, and one raccoon was compared with secondary systemic amyloid from three domestic cats, one dog, one human, and one cow to determine affinity for Congo red dye after treatment of paraffin-embedded tissue sections with potassium permanganate and dilute sulfuric acid. Insular amyloid from all six species was resistant to pretreatment with potassium permanganate, i.e., affinity for Congo red was retained, whereas secondary systemic amyloid from all species was sensitive to the potassium permanganate pretreatment. Other stains did not distinguish between insular and secondary systemic amyloid. The potassium permanganate-Congo red staining procedure thus can be used to differentiate insular from secondary systemic amyloid in the cat and other species. The results also indicate that insular amyloid and secondary systemic amyloid are of different chemical composition and pathogenesis.
Monocytic Leukemia in a Horse
Authors: Burkhardt E. , Saldern F. v. , Huskamp B. 
Published: January 2017

On clinical examination, a six-year-old Hassian gray gelding with a history of impaired performance, slight cough, colic, and edema of the ventral abdomen, prepuce and the legs had reduced skin turgor, pale mucous membranes, forced costoabdominal breathing, reduced venous return, enlarged lymph nodes, and splenomegaly. Hematologic findings revealed anemia, leukocytosis and a high percentage of monocytoid leukemic cells. Generalized lymphadenopathy, splenomegaly, ascites, hydrothorax, and a diffusely thickened gut wall were found at necropsy. Massive infiltration with monocytoid leukemic cells was detected in lymph nodes, spleen, bone marrow, liver, gut wall, kidneys, and choroid plexus. Incubation of living cells obtained from a leukocyte concentrate with latex particles revealed phagocytosis in the leukemic cells on light and electron microscopy. The leukemic cells also had a marked α-naphthyl-acetate and naphthol-AS-acetate esterase activity, but were only weakly positive to naphthol-AS-D-chloroacetate esterase. A very weak alkaline phosphatase activity only was demonstrated in a few leukemic cells. On scanning electron microscopy, the leukemic cells had prominent ruffles and ridge-like profiles. These features of the leukemic cells excluded lymphocytic and granulocytic leukemia, and monocytic leukemia was diagnosed.
Prednisone-Induced Morphologic and Chemical Changes in the Liver of Dogs
Authors: Fittschen C. , Bellamy J. E. C. 
Published: January 2017

Glucocorticoid treatment in dogs is known to cause hepatocellular swelling due to accumulation of cytoplasmic compounds which variably have been identified histochemically as fat, glycogen, or water. In the present study changes in dog liver, after treatment for 15 days with two different doses of oral or intramuscular prednisone, were examined using histological, histochemical, and ultrastructural techniques as well as quantitative chemical analysis. Thirty mongrel dogs were divided into two control groups and three treatment groups of six dogs each. Dogs which received prednisone orally at 1.2 mg/kg body weight/day, or 4 mg/kg body weight/day, respectively, or received intramuscular prednisone injections of 4 mg/kg body weight/day had hepatomegaly due primarily to hepatocellular accumulation of glycogen. Compared to controls, no changes in the hepatic water concentration were observed, whereas the relative amounts of liver fat were decreased slightly and those of protein were decreased markedly. Hepatocellular glycogen could be demonstrated histochemically in tissues fixed in absolute alcohol, but not in tissues treated with aqueous fixative, such as 10% buffered formalin or Bouin's solution. Glycogen deposition occurred predominantly in the midzone of hepatic acini. Affected hepatocytes varied in size and shape. The most severely affected cells were enlarged five to ten fold with glycogen occupying most of the cytoplasmic space restricting the mitochondria, endoplasmic reticulum, and other organelles to a narrow zone around the cell periphery and the nucleus. It was concluded that treatment with prednisone causes hepatomegaly due to glycogenosis in the dog.
The Depressor Supercilii Muscle: Anatomy, Histology, and Cosmetic Implications
Authors: Cook Briggs E. , Lucarelli Mark J. , Lemke Bradley N. 
Published: January 2017

Introduction: This article describes the anatomy and histology of the depressor supercilii muscle and discusses cosmetic implications. Materials and Methods: The depressor supercilii muscle was studied in detail by using gross anatomic dissections carried out on 8 sides of 4 fresh cadaver heads and 10 sides of 5 preserved cadaver heads. Histologic analysis was performed on parasagittal sections of one side of a preserved cadaver head. Measurements were taken on cadaver specimens to determine the insertion point of the depressor supercilii muscle onto the undersurface of the skin. Results: The depressor supercilii muscle was demonstrated to be a muscle distinct from the corrugator supercilii muscle and the medial head of the orbital portion of the orbicularis muscle. The depressor supercilii muscle was noted to be vertical in orientation and redder in color than the orbicularis oculi muscle. The depressor supercilii muscle arose from the frontal process of the maxilla approximately 1 cm above the medial canthal tendon and appeared to originate from 2 distinct heads in most specimens — a novel finding. In specimens containing 2 heads of the depressor supercilii muscle, the angular vessels passed between the 2 muscle heads. In specimens containing 1 muscle head, the angular vessels were found anterior to the muscle. The insertion of the depressor supercilii muscle into the dermis lay approximately 13 to 14 mm directly above the medial can-thal tendon. Discussion: The origin, insertion, and anatomy of the depressor supercilii muscle help it to act as a depressor of the eyebrow. Histologically, the depressor supercilii muscle arises distinctly from bone and has a unique insertion. The depressor supercilii muscle can be addressed and inactivated through the placement of botulinum toxin into its muscle belly or subcutaneously along its course. The depressor supercilii can also be inactivated by surgical resection through an upper eyelid blepharoplasty incision in concert with corrugator supercilii or procerus resection.
Laser Hair Removal and the Influence of Spot Size
Authors: Newman Nathan , Eremia Sorin 
Published: January 2017

Introduction: The purpose of this study is to critically and prospectively examine the role of spot size in laser hair treatment when all other variables are kept the same. Materials and Methods: Fifteen women aged 17 to 37 years were enrolled in this prospective study. Laser hair removal was performed in the axillae, using a 755-nm alexandrite laser with an 8-mm and a 12-mm spot size. Each patient underwent a minimum of 3 and a maximum of 4 treatment sessions spaced 6 weeks apart. Results: Results 6 months after the last treatment were quite good (83% reduction) with the 12-mm spot size but far less impressive (56% reduction) with the 8-mm spot size. In other words, treatment with the 8-mm spot size resulted, on average, in 2.6 times more residual hairs than treatment with the 12-mm spot size. Discussion: Fluences in the range of 30 to 40 J/cm2 with spot sizes of 12 mm or greater are highly effective at achieving long-term hair reduction with a 3-ms-pulse-width 755-nm Alexandrite laser.