bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring drivers and factors of benefit impact reports quality: Retracing a stakeholder theory approach
Authors: Esposito Paolo , Marrone Arcangelo , Pontrelli Vincenzo , Rella Angela 
Published: October 2024

AbstractIn the pursuit of global sustainability, firms play an increasingly pivotal role. In this scenario, Benefit Corporations aim to seamlessly integrate profit‐making endeavors with sustainable practices. This corporate model has spread around the world and in Italy; it was adopted through Law No. 208/2015 introducing Italian Benefit Corporations (BCs). Italian BCs must produce a Benefit Impact Report (BIR) alongside their financial statements, as a strategic communication tool for demonstrating the company's commitment to advancing common societal benefits to stakeholders. Leveraging stakeholder theory, this study adopts a mixed methodological approach that incorporates manual content analysis of BIRs from 132 Italian BCs, combined with a regression model exploring the impact of firm characteristics on the quality of BIRs. Findings highlight a positive relationship between firm size, financial leverage, and profitability on the quality of BIRs. This study is the first to explore the quality of BIRs and their determinants, providing academic and practical implications.
Does AI elevate corporate ESG performance? A supply chain perspective
Authors: Lin Boqiang , Zhu Yitong 
Published: October 2024

AbstractAs a pivotal catalyst for sustainable development, the evolution and integration of AI are propelling both companies and society toward a more efficient trajectory. Utilizing a multi‐period difference‐in‐difference (DID) model, the study assesses the impact of the 2019 China Artificial Intelligence Pilot (AIP) policy on corporate environmental, social, and governance (ESG). The study's findings are the following: (1) Optimizing corporate governance through artificial intelligence (AI), the AIP policy has significantly bolstered the ESG performance of companies in the pilot areas. (2) Mechanistic analysis demonstrates that the AIP policy elevates ESG by bolstering the efficiency of corporate supply chains. (3) Heterogeneity testing shows that the AIP policy exerts a more pronounced effect on non‐state‐owned companies, companies with high energy consumption, and those in the new energy sector. This manuscript furnishes empirical insights for evaluating the policy implications of AI development initiatives.
Omni‐channel customer segmentation: A personalized customer journey perspective
Authors: Van Nguyen Anh Thi , McClelland Robert , Thuan Nguyen Hoang 
Published: October 2024

AbstractAs switching behaviors become more prevalent in omni‐channel retailing, businesses face the challenge of crafting customer journeys that are not only seamless and integrated but also personalized. Personalization at the customer journey level requires a deep understanding of varied customer needs and behaviors. This research segments and profiles omni‐channel customers based on their perceptions, values, channel choices, and switching behaviors. We employed a mixed‐method approach, including 23 in‐depth interviews, four focus groups, and an online survey of 345 omni‐channel customers from electronic goods retailers. Our study identifies four distinct segments–digital switchers, webroomers, showroomers, and offline switchers–each requiring different experiences during their shopping journey. Theoretically, it confirms that customers with varying experience needs interact differently with channels, making the customer journey dynamic and individualistic in an omni‐channel context. Practically, our research suggests segment‐specific features for different channels, enabling managers and retailers to optimize and personalize omni‐channel shopping experiences.
The Second Methylation in Psilocybin Biosynthesis Is Enabled by a Hydrogen Bonding Network Extending into the Secondary Sphere Surrounding the Methyltransferase Active Site
Authors: Hudspeth Jesse , Rogge Kai , Wagner Tobias , Müll Maximilian , Hoffmeister Dirk , Rupp Bernhard , Werten Sebastiaan 
Published: October 2024

AbstractThe Psilocybe cubensis SAM‐dependent methyltransferase, PsiM, catalyzes the last step in the biosynthesis of psilocybin. Likely evolved from monomethylating RNA methyltransferases, PsiM acquired a key amino acid exchange in the secondary sphere of the active site, M247 N, which is responsible for its capacity to dimethylate. Two variants, PsiMN247M and PsiMN247A, were generated to further examine the role of Asn247 for mono‐ and dimethylation in PsiM. Herein, we present the kinetic profiles of both variants and crystal structures at resolutions between 0.9 and 1.0 Å. Each variant was crystallized as a ternary complex with the non‐methylated acceptor substrate, norbaeocystin and S‐adenosyl‐l‐homocysteine, and in a second complex with the cofactor analog, sinefungin, and the monomethylated substrate, baeocystin. Consistent with the inability of the variants to catalyze a second methyl transfer, these structures reveal catalytically non‐productive conformations and a high level of disorder of the methylamine group of baeocystin. Additionally, both variants exhibit destabilization in the β5‐β7 sheets and a conserved β‐turn of the core Rossmann fold, causing 20‐fold reduced substrate binding and 2‐fold lower catalytic efficiency even with norbaeocystin. Our structural and kinetic analyses of the variants suggest that Asn247 is essential to allow enough space in the active site for multiple methylations while also participating in a network of hydrogen bonds that stabilizes secondary structure elements in the immediate vicinity of the active site for optimal methylation of norbaeocystin.
Photolabile ortho‐Nitro‐Benzyl Carbonate as a Permanent Hydroxyl Protecting Group for the Synthesis of Digalactosyl Diacylglycerol
Authors: Zheng Jibin , Chen Hongyu , Shang Jintao , Zhang Lvfeng , Liang Youling , Chang Dongsheng , Yang You 
Published: October 2024

Comprehensive SummaryTraditional protecting groups are often removed under harsh conditions with potentially hazardous reagents, thereby impeding the convenient synthesis of oligosaccharides and glycosides. Herein, we present to utilize the photolabile ortho‐nitro‐benzyl carbonate (oNBC) as a permanent hydroxyl protecting group for stereocontrolled synthesis of glycosides. The Ph3PO‐modulated glycosylation with strongly disarmed per‐O‐oNBC‐protected glycosyl ynenoates preferred to afford glycosides with excellent α‐selectivities via the β‐phosphonium transition state. Based on the oNBC‐mediated galactosylation, synthesis of the glycolipid digalactosyl diacylglycerol (DGDG) containing six double bonds and two esters was achieved in a straightforward manner.
The Role of Inflammation in Early Left Ventricular Thrombus Formation Following ST‐Elevation Myocardial Infarction—A Matched Case‐Control Study
Authors: Litmanowicz Batia , Perelman Moran Gvili , Laufer‐Perl Michal , Topilsky Yan , Banai Shmuel , Shacham Yacov , Khoury Shafik 
Published: October 2024

ABSTRACTBackgroundThere is limited data on the association between inflammation and the formation of early left ventricular thrombus (LVT) following ST‐elevation myocardial infarction (STEMI). This study aimed to explore the predictive value of several inflammatory biomarkers for LVT formation following STEMI.Methods and ResultsOur cohort included 2534 consecutive patients admitted to the cardiac intensive care unit (CICU) with STEMI. The final analysis included 51 patients with LVT and 102 patients without LVT, matched for age, sex, anterior infarct and ejection fraction. Upon admission, patients with LVT had higher white blood cell counts (WBC) (12.8 ± 7 vs. 12.4 ± 4 ×103/µL, p = 0.01), higher absolute neutrophil counts (10.5 ± 4 vs. 8.6 ± 4 ×103/µL, p = 0.003), neutrophil‐to‐lymphocyte ratio (8.2 ± 6 vs. 4.8 ± 4, p = 0.04), and C‐reactive protein (CRP) levels (35.9 ± 62 vs. 18.6 ± 40 mg/L, p = 0.04). Peak values for WBC and CRP were also higher in the LVT group (17.8 ± 8 vs. 14.6 ± 5 ×103/µL, p = 0.003 and 95.8 ± 82 vs. 64.2 ± 76 mg/L, p = 0.02, respectively). In univariate regression analysis, WBC upon admission (OR: 1.12, 95% CI: 1.02–1.21, p = 0.02), peak WBC (OR: 1.09, 95% CI: 1.02–1.17, p = 0.009), neutrophil count upon admission (OR: 1.15, 95% CI: 1.04–1.26, p = 0.004), and peak CRP (OR: 1.01, 95% CI: 1–1.01, p = 0.03) predicted LVT formation, which was also evident in multivariate regression models.ConclusionWBC and neutrophil counts upon admission, as well as peak WBC and CRP, have additional predictive value for LVT formation following STEMI, beyond classical risk factors.
Marker trait association and candidate gene identification for brown rust disease in sugarcane
Authors: Islam Md S. , Qin Lifang , McCord Per H. , Sood Sushma , Zhang Muqing 
Published: October 2024

AbstractBrown rust (caused by Puccinia melanocephala H. & P. Sydow) is one of the most devastating diseases in commercial sugarcane production. It could reduce sugarcane yield by up to 50% depending on the susceptibility levels of cultivars. Breeding disease‐resistant cultivars is the most effective, economical, and environmentally friendly option to control brown rust. A genome‐wide association study was conducted on a field trial using 432 sugarcane clones following an augmented design with two replications. Brown rust was screened using the whorl inoculation method over two crop cycles. The genotype data were obtained through target enrichment sequencing technologies. The gene actions considering six different models and marker dosage effects were included during the marker‐trait analysis. A total of seven, nine, and seven nonredundant marker‐trait associations were identified for plant cane, first ratoon, and across two crop cycles, respectively. The most significant (p‐value 6.17E−20) marker (chr01p59833543) has the additive effect of −0.63 for the diplo‐additive model and reduced disease severity the most (41.35%) due to heterozygote (AG) over homozygote allele (AA) combination in the tested clones. Gene annotation of the monoploid sugarcane genome R570 suggested that six putative candidate genes were co‐located with significant markers associated with brown rust resistance in sugarcane. The putative candidate genes regulated the formation of a cell wall barrier that plays a crucial role in controlling brown rust pathogen infection. The results of this study will open the path to exploiting new resistance sources for brown rust resistance in commercial sugarcane.
The Feasibility of Using Electrostatic Interactions for Immobilizing Ru‐bda Catalysts in Covalent Organic Framework: A Proof‐of‐Concept
Authors: Shao Mengjiao , Jiang Xuesong , Wang Aodi , Tan Guang , Wang Lei 
Published: October 2024

AbstractHeterogenization of molecular catalysts effectively resolves the separation issues of homogeneous catalysts and expands their application scenarios. In recent years, more and more studies have been using non‐covalent interactions to achieve the heterogenization of molecular catalysts. Herein, electrostatic attraction was used to immobilize molecular catalysts, Ru‐bda small molecular catalysts in COF materials, where the charged Ru‐bda catalysts were immobilized in the oppositely charged COF with a high [Ru] loading content of ~0.2 mmol [Ru] g−1 COF. The leakage experiment verified that the immobilization of Ru‐bda catalysts in COF by electrostatic interactions is stable in 0.1 M HClO4 and less than 5 % of molecular Ru‐bda catalysts were leached into the solution in 2 hours. The chemical water oxidation experiment was conducted as a model catalysis reaction to verify the feasibility of using electrostatic interactions for immobilizing Ru‐bda catalysts in COFs. The prepared Ru(bda)@COFs demonstrate a high catalytic activity of 268 μmol L−1 s−1 O2 for chemical water oxidation, illustrating the electrostatic attractions between COF and small molecules that can be used to immobilize homogeneous catalysts in heterogeneous materials. However, the robustness of COF material itself under catalytic conditions should be considered in practical applications.
Traditional healing and medicine in dementia care for Indigenous populations in North America, Australia, and New Zealand: Exploring culturally‐safe dementia care policy from a global perspective
Authors: Shrestha Hom Lal , Shrestha Lucy , McArthur Michael , Rowe Robyn K. , Maar Marion , Walker Jennifer D. 
Published: October 2024

AbstractINTRODUCTIONIn 2018, the World Health Organization recognized traditional healers as community stakeholders in dementia care. This scoping review aimed to summarize the existing dementia care literature regarding strategies for the integration of traditional healing in dementia care and the roles of traditional healers.METHODSA group of Indigenous Elders from Northern Ontario, Canada, guided, reviewed, and validated the research process and findings. The Joanna Briggs Institute approach was applied to a structured search strategy across the CINAHL, Embase, MEDLINE, and PsycINFO databases. A title and abstract screening were completed, followed by a full‐text assessment of the identified manuscripts.RESULTSA total of 143 full manuscripts were reviewed, of which two studies fully met the community‐determined inclusion/exclusion criteria.DISCUSSIONThe integration of traditional healing practices into dementia care offers a pathway to culturally‐safe care for people with dementia. The findings identified policy advocacy as key to engage, educate, and empower traditional healers.Highlights
The WHO recognized traditional healers as community stakeholders in dementia care and prevention worldwide in 2018; however, traditional healers are underrepresented and marginalized in healthcare systems due to the lack of culturally‐safe dementia care (CSDC) policies at community and national levels globally.
Community‐based CSDC models were critically reviewed and validated by local Indigenous community stakeholder consultations.
The result is a call to action to assist the WHO and Alzheimer's Disease International in developing guidelines for CSDC policy improvements with the global Indigenous community for the engagement and empowerment of traditional healers to navigate dementia care and to implement the WHO Global Action Plan on the Public Health Response to Dementia (2017–2025).
Integration of Western biomedical and Indigenous traditional healing and medicine in dementia care in the healthcare system can reduce health disparities and empower traditional healers on a global scale. Indigenous‐led models that include traditional healers in dementia care are critical for improving equity gaps in dementia care for Indigenous Peoples.
Dietary Niche Variation in an Invasive Omnivore: The Effects of Habitat on Feral Pig Resource Use in Hawai‘i
Authors: Peyton Michael S. , Kinney Kealohanuiopuna M. , Knox Sarah , Tredennick Grace , Hotchkiss Sara 
Published: October 2024

ABSTRACTInvasive omnivores may have profound impacts on ecological communities through diet selection, particularly when their functional roles differ from those in their native range. While the threat of feral pigs (Sus scrofa) to native plant communities in Hawai‘i is well known, their trophic dynamics and the drivers of variation in their diet remain understudied. We investigated the feral pig trophic niche on Hawai‘i Island using stable isotopes (13C and 15N) and Bayesian mixing models to identify drivers of variation in resource use. We also reconstructed intra‐individual variability for six subsampled individuals to understand temporal variation in resource use and individual diet specialization. Our results revealed that feral pigs on Hawai‘i Island exhibit a broad trophic niche characterized by diverse diets, with substantial overlap in resource use across districts and habitats. Differences in dietary composition in the transition from forest to open habitat were driven primarily by a decline in invertebrates and an increasing reliance on resources enriched in 15N, which may reflect a shift in protein sources with habitat. Pigs in forested areas exhibited a smaller trophic niche than those in open habitats, largely driven by differences in feeding strategies and resource availability. Diets for subsampled individuals varied little, suggesting feral pig resource‐use strategies in Hawai‘i tend to be relatively stable through time. Individual niche width was relatively narrow compared to that of feral pigs in Hawai‘i at large, indicating the relatively wide feral pig dietary niche is characterized by substantial intraspecific diet specialization, likely as a result of strong intraspecific competition. Understanding the drivers of feral pig resource use offers key information for management strategies aimed at mitigating their ecological impacts in imperiled systems like Hawai‘i.
ZIF‐8 as Potential Vector for Enhanced Target Delivery of Sulfathiazole for the Treatment of Bovine Ruminal Acidosis
Authors: di Nicola Nicola , Paolucci Valentina , Daniele Valeria , Taglieri Giuliana , Crucianelli Marcello , Guidoni Leonardo , Lazzarini Andrea 
Published: October 2024

AbstractThe aim of this paper is enlarging the potential use of ZIF‐8 MOF as drug delivery system (DDS) for antimicrobial molecules, in particular for sulfathiazole, to be employed for the treatment of Sub‐Acute Ruminal Acidosis (SARA) in dairy cows. We therefore optimized (from milligrams to grams) the synthesis methodology for ZIF‐8 MOF, moving from organic solvents to aqueous solution, deeply characterizing the prepared material with X‐ray diffraction (XRD), surface area analyses (BET), electron microscopy (SEM), and thermogravimetric analyses (TGA). Once proved that the synthesis is also reproducible, we tested the stability of the material at physiological and acid pH, controlling material stability over time by checking their crystallinity with XRD. We then optimized sulfathiazole entrapment method to obtain the best material, checking the effective loading with UV‐Vis spectroscopy. Afterwards, we checked the effective entrapment vs physical mixture by means of XRD, SEM and ATR‐MIR spectroscopy. Finally we tested the pH‐responsive drug release by dialyzing the sulfathiazole@ZIF‐8 by UV spectroscopy on the dialysis solution, confirming the strong pH‐dependence of release time of sulfathiazole.
A Squaramide‐Tagged Proline‐Mediated Direct Asymmetric Aldol Addition in the Presence of Water
Authors: Kumari Kiran , Gulam Hussain Khan Akram , Kumar Dhiya Ajay , Easwar Srinivasan 
Published: October 2024

AbstractA squaramide moiety introduced at the C‐4 position of proline produced an organocatalyst that promoted the direct asymmetric aldol addition in the presence of water. A variety of aldol adducts, majorly from the reaction cyclohexanone with aldehydes, were obtained in yields generally in the range of 53–99 %, accompanied by 71–99 % ee and 83 : 17 to >99 : 1 diastereomeric ratios. An asymmetric desymmetrization of 4‐alkyl cyclohexanones was also achieved using the transformation.
Efficient seismic fragility analysis considering uncertainties in structural systems and ground motions
Authors: Kim Jungho , Kim Taeyong 
Published: October 2024

AbstractFragility plays a pivotal role in performance‐based earthquake engineering, which represents the seismic performance of structural systems. To comprehensively understand the structural performance under seismic events, it is necessary to consider uncertainties in the structural model, i.e., epistemic uncertainties. However, considering such uncertainties is challenging due to computational complexity, leading most fragility analyses only to consider the chaotic behavior of ground motions on structural responses, i.e., aleatoric uncertainties. To address this challenge, this study proposes an adaptive algorithm that intertwines with the conventional fragility analysis procedures to consider both aleatoric and epistemic uncertainties. The algorithm introduces Gaussian process‐based metamodels to efficiently consider epistemic uncertainties with a small number of time history analyses. Steel moment‐resisting frame structures and a reinforced concrete building are used to demonstrate the improved efficiency and wide applicability of the proposed method. In each case, the proposed method yields fragility curves consistent with reference solutions but with substantially lower computational effort. Comprehensive discussions are provided regarding ground motion sets, structural types, and definitions of limit‐states to demonstrate the robustness of the proposed approach.
Insights into permafrost aggradation and thawing: A case study of Zonag Lake on the Qinghai–Tibet Plateau using SAR interferometry
Authors: Zhang Zhengjia , Wang Qingxiang , Ma Peifeng , Wang Mengmeng , Jiang Xiucheng 
Published: October 2024

AbstractLakes on the Qinghai–Tibet Plateau (QTP) are important indicators of climate change. The water level and area of Zonag Lake have increased sharply since 2000, and the west lake bottom area was exposed after an outburst of flood in September 2011. The drained basin was exposed to the cold environment, causing rapid permafrost forming. In this paper, time‐series synthetic aperture radar interferometry (InSAR) was utilized to monitor the surface deformation of the drained basin using Sentinel‐1A images within a 4‐year period (2017–2020). This research focused on characterizing the spatial and temporal dynamics of ground deformation and exploring changes in the permafrost base around the drained basin based on the deformation information. The experimental results revealed spatially variable ground deformation, with long‐term deformation rates ranging from −78.3 mm/year to 72.8 mm/year and seasonal amplitudes of 0–14 mm. Subsidence was prominent in the lakeshore, the thermokarst region and the slope drainage area, indicative of the thawing of ice‐rich permafrost. Conversely, uplift was concentrated in the exposed unconsolidated sediment region, with a maximum displacement of 110 mm over the nearly 4‐year observation period, suggesting ground ice aggradation. The uplift information was used to estimate the change in the permafrost base in the drained basin, yielding a maximum value of 4 m. The estimated permafrost base change closely aligned with simulated results, with an error of 0.28 m. This study demonstrates the capability of InSAR in monitoring permafrost stability and improving the understanding of the dynamic permafrost formation process.
A Functional Analysis of Inflorescence Architecture in Musa L. (Musaceae)
Authors: Turner David W. , Gibbs D. Jane , Ocimati Walter , Blomme Guy 
Published: October 2024

ABSTRACTInflorescence architecture underpins sexual reproduction in wild Musa species and productivity in edible banana cultivars. In a functional analysis, we identified the apical inflorescence and lateral ‘cushion’ meristems and the change in flower type as the three primary components that generate inflorescence architecture. Five genotypes of two clone sets of edible plantains (Musa AAB) were grown for four generations along an elevation gradient (1100–2200 m, 16°C–24°C) straddling the equator in the humid highlands of East Africa. The data consisted of reproductive peduncle length at harvest (Pr), fruit per hand (Fh) and hands per bunch (Hb). The activity of the apical inflorescence meristem drives peduncle length and generates lateral ‘cushion’ meristems which determine Fh. However, Hb is determined by a change in flower type—from fruit forming to non‐fruit forming. Site temperature affected Hb more than Fh, while the development of the genet (rhizome) changed the allocation of resources between Hb and Fh, independently of the effect of site temperature. Clone sets differed in their response to genet development. Cooler temperatures reduced the number of fruit‐forming flowers in an inflorescence and changed the balance away from female towards male flowers. In banana breeding schemes, manipulating inflorescence components independently raises options for producing genotypes better suited to markets, environments and cultural practices.