bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tomato variety trials for productivity and quality in organic hoop house versus open field management
Authors: Healy G.K. , Emerson B.J. , Dawson J.C. 
Published: January 2017

AbstractTomatoes are a profitable direct-market crop for diversified Midwestern farmers. Unfortunately, many tomatoes with the flavor and quality characteristics consumers desire (such as heirloom varieties) lack agronomic traits important to organic farmers. Hoop-house production offers potentially higher yields and quality than field-grown tomatoes, and has become a popular option for organic farmers. This study compares 19 varieties of tomatoes in both organic hoop house and field conditions, to identify high-performing varieties for future plant breeding, and to characterize the effect of hoop houses on productivity and quality traits. We found that tomatoes grown in a hoop house had significantly higher yield, lower disease severity and higher °Brix (soluble sugars) than those grown in an adjacent field; and that management (hoop house versus field) had significantly more influence over those traits than other variables (variety, market class or year). This lack of varietal differences between management systems will simplify breeding efforts aimed at introducing varieties for hoop house production.
Case management in complex fraud trials: actors and strategies in achieving procedural efficiency
Authors: Jordanoska Aleksandra 
Published: January 2017

AbstractTrials of complex fraud cases have raised numerous contentious issues in terms of procedural fairness and public resources expenditure. This paper examines the management of complex fraud trials through the lens of managerialism in the criminal justice system, analysing its effects upon procedural efficiency of the trial. The paper draws on qualitative data gathered from observations of insider-dealing trials, and interviews with prosecuting and defence lawyers and a trial judge. The findings reveal that, in practice, although dangers to procedural efficiency are constantly present throughout the trial, its successful management depends on a combination of factors vested in the actors involved and the strategies used. Whilst the increased efficiency of the trials is a reflection of managerial approaches in case management, this does not necessarily indicate a negative development in the area of the control of business misconduct, and managerialism may not be necessarily entirely undesirable in the criminal justice system.
Storytelling in Jazz Work as Retrospective Collaboration
Authors: OKIJI FUMI 
Published: January 2017

AbstractStorytelling has proved to be a useful metaphor in jazz commentary and analysis. Within such literature it is invariably solos, portrayed as discrete cultural articles, that “tell a story” through their adherence to internal coherence and logic. This prized autonomy is modeled on that which we find in the modern European tradition. Pathbreaking studies by scholars such as Ingrid Monson, Paul Berliner, and Keith Sawyer have redressed this hegemony in highlighting the importance of collaborative work in jazz. This essay needs to be considered a contribution to this focus. Yet approaches that emphasize interaction among band members tend toward dialogical metaphors and analytical frameworks that marginalize forms of creative “collaboration” that can occur retrospectively between musicians and vocalists who may not have even met. Drawing from Walter Benjamin's essay “The Storyteller: Nikolai Leskov,” this essay argues that storytelling in jazz is an intergenerational, accumulative effort in which we see a story continue to unfold with each new telling. It shows that there is generative tension between a musician holding on to his or her distinctive characteristics and approach, and their commitment to sharing (in) the story. Storytelling in jazz involves musicians adding “transparent layers” to the tradition, contributing to musical material, and collaborating with others (both contemporary and temporally distant) in a manner in which personal distinction is actively maintained. Through a consideration of John Coltrane's ideas concerning the centrality of community to the practice, storytelling in jazz is shown to be of extramusical social significance also.
Teeth complexity, hypsodonty and body mass in Santacrucian (Early Miocene) notoungulates (Mammalia)
Authors: Cassini Guillermo H. , Hernández Del Pino Santiago , Muñoz Nahuel A. , Acosta M. V. Walter G. , Fernández Mercedes , Bargo M. Susana , Vizcaíno Sergio F. 
Published: January 2017

ABSTRACTNotoungulates, native South American fossil mammals, have been recently objective of several palaeoecological studies. Ecomorphology and biomechanics of the masticatory apparatus, together with micro and mesowear analyses on tooth enamel, were applied in order to understand their palaeobiology. In particular, the relationship between some dental traits (hypsodonty, occlusal surface area and complexity) and body mass is still poorly understood. These features were measured by means of the hypsodonty index (HI), occlusal surface area (OSA) and tooth area (OTA), enamel crest complexity (ECC) and length (OEL). The relationships between these indices were evaluated in five pan-contemporaneous Santacrucian Notoungulata genera from Patagonia: Adinotherium and Nesodon (Toxodontia), Interatherium, Protypotherium and Hegetotherium (Typotheria). While OSA, OTA and OEL were size dependent and strongly correlated, HI and ECC were size independent. All notoungulates analysed have very hypsodont teeth, indicating high rates of tooth wear in response to an increase of abrasives consumed with the food; their tooth occlusal area and complexity could be related to chewing efforts associated with the toughness of the plants consumed. HI, OSA and ECC were considered useful for palaeoecological reconstructions, but the results presented here show that these three features are integrated as a complex, so should not be evaluated separately.
The forelimb of †Cyonasua sp. (Procyonidae, Carnivora): ecomorphological interpretation in the context of carnivorans
Authors: Tarquini J. , Toledo N. , Morgan C. C. , Soibelzon L. H. 
Published: January 2017

ABSTRACTThe procyonid †Cyonasua is endemic to South America and recorded from the Late Miocene to the Early Pleistocene. This paper studies the forelimb of †Cyonasua sp. (late Pliocene of Miramar, Argentina), using an ecomorphological approach to infer morphological adaptations linked to substrate preference and locomotory mode, as well as to grasping and digging ability. Twenty linear measurements of forelimb and pectoral girdle were taken from †Cyonasua sp. and a sample of 87 specimens of extant carnivoran families (Procyonidae, Mustelidae, Ursidae, Viverridae, Canidae and Felidae). Raw values were transformed to minimise the effect of size. Morphological variation was explored by principal component analysis (PCA); substrate preference and locomotory mode were further analysed by multivariate analysis of variance (MAV) and discriminant analysis (DA); grasping and digging ability were analysed by DA. In the PCA morphospace, †Cyonasua sp. occupied a unique position, close to extant procyonids. DA classified it as non-specialised digger with poor grasping ability. The results lead to the interpretation of †Cyonasua sp. as having a moderately stabilised elbow joint with poor pronation–supination, although some climbing skills cannot be ruled out. Thus, †Cyonasua sp. could have had generalised habits, in agreement with reconstructed palaeoenvironmental conditions.
Experimental Evidence on the Relationship Between Candidate Funding Sources and Voter Evaluations
Authors: Dowling Conor M. , Miller Michael G. 
Published: January 2017

AbstractMoney comes from a variety of sources in American elections. It is unclear however whether voters’ knowledge about a candidate's funding portfolio influences how that candidate is evaluated. We present the results of two survey experiments in which we randomly assigned the composition of donors from various categories to a hypothetical candidate. We find that on average a candidate described as having received a majority of his contributions from individuals is evaluated more highly than one who received a majority of his contributions from interest groups. We also find that when it comes to self-financing a campaign, using private sector money is more beneficial to candidates than using inherited money, but only when the candidate is a member of the same party as the voter. Our results have implications for campaign strategy, academic debates concerning the effect of money on elections, and policy debates concerning the effects of increased campaign finance disclosure.
Förderung sprachlicher Kompetenzen – Das Potenzial der Familiensprache für den Wortschatzerwerb aus Texten
Authors: McElvany Nele , Ohle Annika , El-Khechen Wahiba , Hardy Ilonca , Cinar Melihan 
Published: January 2017

Zusammenfassung. Sprachliche Kompetenzen wie der Wortschatz sind zentrale Voraussetzungen für schulischen Erfolg und gesellschaftliche Integration. Vor dem Hintergrund der Theory of Learning from Context ( Sternberg & Powell, 1983 ) und dem Modell des Textverstehens ( Kintsch, 1998 ) wird untersucht, in welchem Umfang Kinder nichtdeutscher Familiensprache (N = 143) neue Wörter aus Lesetexten lernen und ob die Einbeziehung der (türkischen) Familiensprache zur Wortschatzförderung im Deutschen zusätzlichen Nutzen hat. Die Analysen im Rahmen eines experimentellen Prä-Post-Testdesigns mit vier Bedingungen, in denen der Einbezug der Familiensprache manipuliert wurde, und mehrwöchiger Interventionszeit mit 15 Leseeinheiten ergeben ein Befundmuster für die Wortschatzveränderung nach dem Lesen der Texte, bei dem sich kein zusätzliches Potenzial des Einbezugs der Familiensprache zeigt. Die Befunde werden hinsichtlich ihrer Bedeutung für Theorie und zukünftige Forschungsdesiderata sowie die schulische Praxis diskutiert.
Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-κB signaling by degrading TRAF2-associated cIAP1 in cancer cells
Authors: Mitsuuchi Y , Benetatos CA , Deng Y , Haimowitz T , Beck SC , Arnone MR , Kapoor GS , Seipel ME , Chunduru SK , McKinlay MA , Begley CG , Condon SM 
Published: January 2017

AbstractThe inhibitor of apoptosis (IAP) proteins have pivotal roles in cell proliferation and differentiation, and antagonizing IAPs in certain cancer cell lines results in induction of cell death. A variety of IAP antagonist compounds targeting the baculovirus IAP protein repeat 3 (BIR3) domain of cIAP1have advanced into clinical trials. Here we sought to compare and contrast the biochemical activities of selected monovalent and bivalent IAP antagonists with the intent of identifying functional differences between these two classes of IAP antagonist drug candidates. The anti-cellular IAP1 (cIAP1) and pro-apoptotic activities of monovalent IAP antagonists were increased by using a single covalent bond to combine the monovalent moieties at the P4 position. In addition, regardless of drug concentration, treatment with monovalent compounds resulted in consistently higher levels of residual cIAP1 compared with that seen following bivalent compound treatment. We found that the remaining residual cIAP1 following monovalent compound treatment was predominantly tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2)-associated cIAP1. As a consequence, bivalent compounds were more effective at inhibiting TNF-induced activation of p65/NF-κB compared with monovalent compounds. Moreover, extension of the linker chain at the P4 position of bivalent compounds resulted in a decreased ability to degrade TRAF2-associated cIAP1 in a manner similar to monovalent compounds. This result implied that specific bivalent IAP antagonists but not monovalent compounds were capable of inducing formation of a cIAP1 E3 ubiquitin ligase complex with the capacity to effectively degrade TRAF2-associated cIAP1. These results further suggested that only certain bivalent IAP antagonists are preferred for the targeting of TNF-dependent signaling for the treatment of cancer or infectious diseases.
Universal and uniquely human factors in spontaneous number perception
Authors: Ferrigno Stephen , Jara-Ettinger Julian , Piantadosi Steven T. , Cantlon Jessica F. 
Published: January 2017

AbstractA capacity for nonverbal numerical estimation is widespread among humans and animals. However, it is currently unclear whether numerical percepts are spontaneously extracted from the environment and whether nonverbal perception is influenced by human exposure to formal mathematics. We tested US adults and children, non-human primates, and numerate and innumerate Tsimane’ adults on a quantity task in which they could choose to categorize sets of dots on the basis of number alone, surface area alone or a combination of the two. Despite differences in age, species and education, subjects are universally biased to base their judgments on number as opposed to the alternatives. Numerical biases are uniquely enhanced in humans compared to non-human primates, and correlated with degree of mathematics experience in both the US and Tsimane’ groups. We conclude that humans universally and spontaneously extract numerical information, and that human nonverbal numerical perception is enhanced by symbolic numeracy.
Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD
Authors: Yu Xiaohua , Zhang Yong , Li Tingting , Ma Zhao , Jia Haixue , Chen Qian , Zhao Yixia , Zhai Lili , Zhong Ran , Li Changyin , Zou Xiaoting , Meng Jiao , Chen Antony K. , Puri Pier Lorenzo , Chen Meihong , Zhu Dahai 
Published: January 2017

AbstractLong non-coding RNAs (lncRNAs) are important regulators of diverse biological processes. Here we report on functional identification and characterization of a novel long intergenic non-coding RNA with MyoD-regulated and skeletal muscle-restricted expression that promotes the activation of the myogenic program, and is therefore termed Linc-RAM (Linc-RNA Activator of Myogenesis). Linc-RAM is transcribed from an intergenic region of myogenic cells and its expression is upregulated during myogenesis. Notably, in vivo functional studies show that Linc-RAM knockout mice display impaired muscle regeneration due to the differentiation defect of satellite cells. Mechanistically, Linc-RAM regulates expression of myogenic genes by directly binding MyoD, which in turn promotes the assembly of the MyoD–Baf60c–Brg1 complex on the regulatory elements of target genes. Collectively, our findings reveal the functional role and molecular mechanism of a lineage-specific Linc-RAM as a regulatory lncRNA required for tissues-specific chromatin remodelling and gene expression.
Limiting parental feedback disrupts vocal development in marmoset monkeys
Authors: Gultekin Yasemin B. , Hage Steffen R. 
Published: January 2017

AbstractVocalizations of human infants undergo dramatic changes across the first year by becoming increasingly mature and speech-like. Human vocal development is partially dependent on learning by imitation through social feedback between infants and caregivers. Recent studies revealed similar developmental processes being influenced by parental feedback in marmoset monkeys for apparently innate vocalizations. Marmosets produce infant-specific vocalizations that disappear after the first postnatal months. However, it is yet unclear whether parental feedback is an obligate requirement for proper vocal development. Using quantitative measures to compare call parameters and vocal sequence structure we show that, in contrast to normally raised marmosets, marmosets that were separated from parents after the third postnatal month still produced infant-specific vocal behaviour at subadult stages. These findings suggest a significant role of social feedback on primate vocal development until the subadult stages and further show that marmoset monkeys are a compelling model system for early human vocal development.
Centrality in the host–pathogen interactome is associated with pathogen fitness during infection
Authors: Crua Asensio Núria , Muñoz Giner Elisabet , de Groot Natalia Sánchez , Torrent Burgas Marc 
Published: January 2017

AbstractTo perform their functions proteins must interact with each other, but how these interactions influence bacterial infection remains elusive. Here we demonstrate that connectivity in the host–pathogen interactome is directly related to pathogen fitness during infection. Using Y. pestis as a model organism, we show that the centrality-lethality rule holds for pathogen fitness during infection but only when the host–pathogen interactome is considered. Our results suggest that the importance of pathogen proteins during infection is directly related to their number of interactions with the host. We also show that pathogen proteins causing an extensive rewiring of the host interactome have a higher impact in pathogen fitness during infection. Hence, we conclude that hubs in the host–pathogen interactome should be explored as promising targets for antimicrobial drug design.
Acute effects of a beverage containing bitter melon extract (CARELA) on postprandial glycemia among prediabetic adults
Authors: Boone C H , Stout J R , Gordon J A , Redd M J , Church D D , Oliveira L P , Fukuda D H , Hoffman J R 
Published: January 2017

Abstract
Background:
Acute ingestion of bitter melon (BM) has been shown to suppress the postprandial glycemic response in diabetics, but its impact on glucose regulation among individuals with impaired glucose tolerance is unclear. Moreover, one’s glucose tolerance level may influence the effectiveness of BM. This study aimed to examine the acute effects of a beverage containing BM extract on blood glucose regulation during an oral glucose tolerance test (OGTT) among prediabetics.

Methods:
Ten prediabetic adults completed two OGTTs—glucose only (D2) and glucose+BM (D3). Responders were identified as subjects whose area under the glucose curve (AUCglu) during D3 was lower than D2. To compare the acute effects of the beverage among individuals with varying glucose tolerance levels, subjects were grouped by their glucose response pattern—Fastpeak (peak glucose (Glupeak) at 30 min postglucose (30P)) and Slowpeak (Glupeak after 30P).

Results:
During D3, responders (n=5) experienced a 13.2% reduction in AUCglu (95% confidence interval (CI): −18.1% to −8.3%), 12.2% reduction in mean glucose (95% CI: −17.3% to −7.0%) and 10.6% reduction in Glupeak (95% CI: −17.5% to −3.7%); plasma glucose was reduced by 9.1% at 30P (95% CI: −15.6% to −2.6%), −24.0% at 60P (95% CI: −36.8% to −11.2%) and −20.0% at 90P (95% CI: −35.8% to −4.2%) during D3. No between-trial differences were noted for Fastpeak or Slowpeak.

Conclusions:
Acute ingestion of BM prior to the second OGTT (D3) led to a reduced postprandial glucose response in 50% of the subjects but did not affect the insulin response. Furthermore, the effectiveness of the beverage was seemingly uninfluenced by the subjects’ glucose tolerance level. Although BM has shown to aid blood glucose management in diabetics, it remains uncertain why only a portion of subjects responded positively to the BM extract in the current study.
WNT/β-catenin signaling regulates mitochondrial activity to alter the oncogenic potential of melanoma in a PTEN-dependent manner
Authors: Brown K , Yang P , Salvador D , Kulikauskas R , Ruohola-Baker H , Robitaille A M , Chien A J , Moon R T , Sherwood V 
Published: January 2017

AbstractAberrant regulation of WNT/β-catenin signaling has a crucial role in the onset and progression of cancers, where the effects are not always predictable depending on tumor context. In melanoma, for example, models of the disease predict differing effects of the WNT/β-catenin pathway on metastatic progression. Understanding the processes that underpin the highly context-dependent nature of WNT/β-catenin signaling in tumors is essential to achieve maximal therapeutic benefit from WNT inhibitory compounds. In this study, we have found that expression of the tumor suppressor, phosphatase and tensin homolog deleted on chromosome 10 (PTEN), alters the invasive potential of melanoma cells in response to WNT/β-catenin signaling, correlating with differing metabolic profiles. This alters the bioenergetic potential and mitochondrial activity of melanoma cells, triggered through regulation of pro-survival autophagy. Thus, WNT/β-catenin signaling is a regulator of catabolic processes in cancer cells, which varies depending on the metabolic requirements of tumors.
A dataset of human decision-making in teamwork management
Authors: Yu Han , Shen Zhiqi , Miao Chunyan , Leung Cyril , Chen Yiqiang , Fauvel Simon , Lin Jun , Cui Lizhen , Pan Zhengxiang , Yang Qiang 
Published: January 2017

AbstractToday, most endeavours require teamwork by people with diverse skills and characteristics. In managing teamwork, decisions are often made under uncertainty and resource constraints. The strategies and the effectiveness of the strategies different people adopt to manage teamwork under different situations have not yet been fully explored, partially due to a lack of detailed large-scale data. In this paper, we describe a multi-faceted large-scale dataset to bridge this gap. It is derived from a game simulating complex project management processes. It presents the participants with different conditions in terms of team members’ capabilities and task characteristics for them to exhibit their decision-making strategies. The dataset contains detailed data reflecting the decision situations, decision strategies, decision outcomes, and the emotional responses of 1,144 participants from diverse backgrounds. To our knowledge, this is the first dataset simultaneously covering these four facets of decision-making. With repeated measurements, the dataset may help establish baseline variability of decision-making in teamwork management, leading to more realistic decision theoretic models and more effective decision support approaches.
Two replications of an investigation on empathy and utilitarian judgement across socioeconomic status
Authors: Babcock Sarah , Li Yixian , Sinclair Vanessa M. , Thomson Clint , Campbell Lorne 
Published: January 2017

AbstractResearch by Côté, Piff, and Willer (2013) found that through the induction of empathy in an experimental condition, the association between socioeconomic status (SES) and utilitarian moral judgment was diminished. Participant self-reported income interacted with experimental condition such that high SES participants who empathized with a disadvantaged group member redistributed fewer experimental dollars during an online task at the losing member’s expense. This suggests that lower levels of empathy could help explain utilitarian decision-making in high SES individuals. Two pre-registered, high-powered replications were conducted in order to assess the magnitude and reliability of this finding. While the first replication attempt failed to uncover the effect, the second attempt found a pattern consistent with the original study. A meta-analysis of the replication attempts with the original author's interaction effects was conducted. The confidence interval of the meta-analytic effect suggests that the true effect size may be as robust as reported by the original authors, or may be close to zero. Implications of the results found in the replication attempts are discussed.