bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term successful closure of a percutaneous intragastric trocar tract with crossing full-thickness sutures in a porcine model
Authors: Storm Andrew , Aihara Hiroyuki , Skinner Matthew , Ryou Marvin , Thompson Christopher 
Published: December 2017

Abstract
Background and study aims A novel intragastric trocar placed using a percutaneous endoscopic gastrostomy technique enables the use of laparoscopic tools and procedures, including tissue stapling, cutting, suturing, and retraction. The aim of this porcine study was to determine long-term success of crossing full-thickness sutures in closure of the tract upon trocar withdrawal.
Methods 10 trocars were placed in 5 animals. Each animal underwent a standardized tissue resection using a 5-mm stapler under gastroscopic guidance, and two full-thickness, absorbable, crossing sutures were used to close the trocar tracts. The animals were monitored for 35 days and then euthanized for necropsy.
Results All five animals survived without sign of infection or distress. Nine of the 10 trocar sites healed completely without any adverse findings. A single site developed a gastrocutaneous fistula. On necropsy, there was no evidence of intra-abdominal infection or abscess.
Conclusions Full-thickness crossing sutures appeared to be effective in long-term closure of an intragastric trocar tract. Given the ease of placement and success of this simple closure method, this device may prove clinically useful to the endoscopist performing complex procedures in the endoscopy suite.
2.2 Catalytic Oxidations with Hypervalent Iodine
Authors: Singh F. V. , Wirth T. 
Published: December 2017

AbstractHypervalent iodine chemistry is a very active research area in both organic synthesis and natural product chemistry. Hypervalent iodine reagents have been used to perform various oxidative transformations under mild reaction conditions. These reagents have received particular attention since the first reports, in 2005, that they can act as catalysts. Since then, various hypervalent iodine catalyzed oxidative functionalizations, such as oxidations of alcohols and phenols, α-functionalizations of carbonyl compounds, cyclizations, and rearrangements have been successfully achieved. Several catalytic reactions have been developed using hypervalent iodine reagents as catalysts, while in other reactions iodoarenes have been used as precatalyst to generate active iodine(III) or iodine(V) species in situ. This chapter highlights various aspects of hypervalent iodine-catalyzed oxidation reactions, including asymmetric variants.
9 Catalytic Aerobic Oxidation of Phenols
Authors: Lumb J.-P. , Esguerra K. V. N. 
Published: December 2017

AbstractPhenols are ubiquitous motifs in nature and their aerobic oxidation is implicated in the biosynthesis of a wide variety of biologically relevant compounds and polymeric materials. This chapter outlines notable catalytic aerobic oxidations of phenols, and includes recent advances in oxidative dimerizations, polymerizations and oxygenation reactions as well as key advances in copper-mediated phenol functionalization. Specifically, this chapter focuses on the synthesis of poly(1,4-phenylene oxides), biphenols, quinones, Pummerer’s ketones, and oxepinobenzofurans.
11 Oxidation of Amines and N-Hetarenes
Authors: Jiao N. , Li Z. 
Published: December 2017

AbstractThe oxidation of amines and hetarenes are significant transformations that have been widely applied in synthetic organic chemistry. In this chapter, the oxidation of primary, secondary, and tertiary amines, affording imines, nitriles, amides, carbonyls, oximes, nitro compounds, diazenes and their oxides, nitrones, hydrazines, and N-oxides, as well as the oxidation of hetarenes including pyridines, azoles, pyrroles, indoles, guanines, and adenines, are comprehensively discussed. In addition to traditional organometallic catalysis to fulfill these oxidation reactions, some advanced approaches such as photocatalysis, biochemical catalysis, and biomimetic catalysis are also described.
1.11 Reduction of Sulfur Compounds Using Metal Catalysts
Authors: Kaneda K. , Mitsudome T. 
Published: December 2017

AbstractHomogeneous and heterogeneous metal catalysts based on molybdenum, rhenium, ruthenium, and platinum promote the reduction of sulfur compounds such as sulfoxides, sulfones, and disulfides by using alcohols or molecular hydrogen as reductants.
Nombres deverbales con sufijos aumentativos
Authors: Martín García Josefa 
Published: December 2017

Abstract
This paper focuses on deverbal nominalizations with the suffix –ón in modern Spanish, bearing in mind their morphological, syntactic and semantic properties. The suffix –ón gives rise to three types of nominalizations, according to the event structure of the verbal base: resultant object nominalization (rozón), resultant state nominalization (apagón) and punctual action (empujón). These nominalizations do not inherit the event structure of the verb, so they have few verbal properties. All nominalizations with –ón are countable (even nominalizations built on atelic verb, such as acelerón), and all of them exhibit the same meaning related to the sudden and brusque development of the action. In this sense, the suffix –ón fixes the syntactic and semantic content of the nominalization, so that this suffix is semantically specified and it is opposed to other nominalising suffixes because it denotes punctual actions or results reached once the action is developed suddenly and with brusqueness.
Le impronte del traduttore
Authors: Schwartz Cecilia 
Published: December 2017

Sommario
Drawing on Antoine Berman’s theory of translation as a critical act, this article analyzes the Swedish translation of Giovanni Verga's
masterpiece I Malavoglia. The actual translation analysis therefore takes as its starting point a pre-analysis that
highlights the translator’s individual motives to deviate from the source text. The results show that the Swedish translator has done
extensive changes to Verga’s polyphonic novel, giving it a more homogeneous form. Drawing on theoretical ideas on the translator’s
unconscious and habitus, the article shows that the translator has downplayed the novel’s expressive and vernacular traits
as well as the patriarchal perspectives, emphasizing instead the novel’s religious paths.
Policy Shocks and Market‐Based Regulations: Evidence from the Renewable Fuel Standard
Authors: Lade Gabriel E. , Lin Lawell C.‐Y. Cynthia , Smith Aaron 
Published: December 2017

AbstractThe Renewable Fuel Standard mandates large increases in U.S. biofuel consumption and is implemented using tradable compliance credits known as RINs. In early 2013, RIN prices soared, causing the regulator to propose reducing future mandates. We estimate empirically the effect of three “policy shocks” that reduced the expected mandates in 2013. We find that the largest of these shocks decreased the value of the fuel industry's 2013 compliance obligation by $7 billion. We then study the effects of the shocks on commodity markets and the market value of publicly‐traded biofuel firms. Results show that the burden of the mandate reductions fell primarily on advanced biofuel firms and commodity markets of the marginal compliance biofuel. We argue that the policy shocks reduced the incentive to invest in the technologies required to meet the future objectives of the RFS, and discuss alternative policy designs to address the problems that arose in 2013.
IndeCut evaluates performance of network motif discovery algorithms
Authors: Ansariola Mitra , Megraw Molly , Koslicki David 
Published: December 2017

Abstract

Motivation
Genomic networks represent a complex map of molecular interactions which are descriptive of the biological processes occurring in living cells. Identifying the small over-represented circuitry patterns in these networks helps generate hypotheses about the functional basis of such complex processes. Network motif discovery is a systematic way of achieving this goal. However, a reliable network motif discovery outcome requires generating random background networks which are the result of a uniform and independent graph sampling method. To date, there has been no method to numerically evaluate whether any network motif discovery algorithm performs as intended on realistically sized datasets—thus it was not possible to assess the validity of resulting network motifs.

Results
In this work, we present IndeCut, the first method to date that characterizes network motif finding algorithm performance in terms of uniform sampling on realistically sized networks. We demonstrate that it is critical to use IndeCut prior to running any network motif finder for two reasons. First, IndeCut indicates the number of samples needed for a tool to produce an outcome that is both reproducible and accurate. Second, IndeCut allows users to choose the tool that generates samples in the most independent fashion for their network of interest among many available options.

Availability and implementation
The open source software package is available at https://github.com/megrawlab/IndeCut.

Supplementary information
Supplementary data are available at Bioinformatics online.
Re-assessing the Validity of the Opioid Risk Tool in a Tertiary Academic Pain Management Center Population
Authors: Clark Meredith R , Hurley Robert W , Adams Meredith C B 
Published: December 2017

AbstractObjectiveTo analyze the validity of the Opioid Risk Tool (ORT) in a large. diverse population.DesignA cross-sectional descriptive study.SettingAcademic tertiary pain management center.SubjectsA total of 225 consecutive new patients, aged 18 years or older.MethodsData collection included demographics, ORT scores, aberrant behaviors, pain intensity scores, opioid type and dose, smoking status, employment, and marital status.ResultsIn this population, we were not able to replicate the findings of the initial ORT study. Self-report was no better than chance in predicting those who would have an opioid aberrant behavior. The ORT risk variables did not predict aberrant behaviors in either gender group. There was significant disparity in the scores between self-reported ORT and the ORT supplemented with medical record data (enhanced ORT). Using the enhanced ORT, high-risk patients were 2.5 times more likely to have an aberrant behavior than the low-risk group. The only risk variable associated with aberrant behavior was personal history of prescription drug misuse.ConclusionsThe self-report ORT was not a valid test for the prediction of future aberrant behaviors in this academic pain management population. The original risk categories (low, medium, high) were not supported in the either the self-reported version or the enhanced version; however, the enhanced data were able to differentiate between high- and low-risk patients. Unfortunately, without technological automation, the enhanced ORT suffers from practical limitations. The self-report ORT may not be a valid tool in current pain populations; however, modification into a binary (high/low) score system needs further study.
Clinical Outcomes Using Oversized Back Plates in Type I Boston Keratoprosthesis
Authors: Kaufman Aaron R. , Cruzat Andrea , Colby Kathryn A. 
Published: December 2017

Objectives:
To examine clinical outcomes of oversized titanium back plates in type I Boston keratoprosthesis (KPro) implantation.

Methods:
Retrospective study of 22 sequential eyes (20 patients) undergoing type I KPro implantation with an oversized titanium back plate (larger than trephined wound diameter by 1.0 mm or more), performed by a single surgeon (K.A.C.) from June 2010 to November 2014. Data were collected regarding preoperative eye characteristics, surgical details, and postoperative clinical outcomes.

Results:
Mean follow-up time per eye was 24.1±14.9 months. All eyes had improved vision after surgery; 13 eyes (59.1%) maintained visual acuity improvement at last follow-up. Initial KPro's were retained in 19 eyes (86.4%); one eye required KPro replacement. Primary retroprosthetic membrane (RPM) developed in three eyes (13.6%), with similar occurrence in aniridic (14.3%) and nonaniridic eyes (13.3%). Secondary RPM's developed in two eyes (9.1%) after vitritis (one eye) and retinal and choroidal detachment (one eye). Glaucoma was a common comorbidity: 2 of 14 eyes (14.3%) with preoperative glaucoma had glaucoma progression, and 4 of 8 eyes (50.0%) without preoperative glaucoma developed glaucoma postoperatively. Other postoperative complications included retinal detachment (5 eyes, 22.7%) and idiopathic vitritis (3 eyes, 13.6%).

Conclusions:
Oversized titanium KPro back plates are associated with a low rate of primary RPM formation and may have particular utility in reducing primary RPM formation in aniridic eyes. Glaucoma remains a challenge in postoperative KPro management. Complex eyes, at increased risk of postoperative complications, require careful management.
Differences in the Alignment Pattern of the Maxillary Dental Arch Following Fixed Orthodontic Treatment in Patients With Bilateral Cleft Lip and Palate: Anteroposterior-Collapsed Arch Versus Transverse-Collapsed Arch
Authors: Hong Mihee , Baek Seung-Hak 
Published: December 2017

Abstract
The purpose of this study was to investigate differences in the alignment pattern of the collapsed maxillary arch following fixed orthodontic treatment (FOT) in bilateral cleft lip and palate (BCLP) patients according to collapse type. Fifteen BCLP patients were divided into Group 1 (anteroposterior-collapsed arch, n = 7) and Group 2 (transverse-collapsed arch, n = 8) according to maxillary arch shape before FOT. Linear and angular variables of lateral cephalograms and dental models were evaluated before (T1) and after FOT (T2), and statistical analysis was performed. In cephalometric measurements at T1, both the groups exhibited retrusive maxillae, a Class III relationship, and lingual inclination of U1-SN. At T2, significant improvement of U1-SN was observed in both the groups (P < 0.01 in Group 1; P < 0.05 in Group 2). In the model measurements at T1, the inter-second premolar width (IP2W), inter-first molar width (IM1W), and left segmental angle were smaller in Group 2 than in Group 1 (IP2W, P < 0.001; IM1W, P < 0.05; LSA, P < 0.05). From T1 to T2, the arch width increased significantly in Group 2 (inter-canine width, IP1W, IP2W, and IM1W; all P < 0.05), but not in Group 1. Therefore, there were significant differences in ΔIP2W (2.4 mm versus 14.9 mm, P < 0.01) and ΔIM1W (−0.7 mm versus 5.9 mm, P < 0.001) between Groups 1 and 2. In both the groups, the molar depth and right and left segmental angles increased significantly, while the premaxillary rotation angle decreased significantly (molar depth, RSA, LSA, and PMRA; all P < 0.05). The alignment strategy for the maxillary premolar and molar areas should be modified according to arch shape in BCLP patients.
Population genomics of hypervirulentKlebsiella pneumoniaeclonal group 23 reveals early emergence and rapid global dissemination
Authors: Lam Margaret MC , Wyres Kelly L , Duchêne Sebastian , Wick Ryan R , Judd Louise M , Gan Yunn-Hwen , Hoh Chu-Han , Achuleta Sophia , Molton James S , Kalimuddin Shirin , Koh Tse Hsien , Passet Virginie , Brisse Sylvain , Holt Kathryn E 
Published: December 2017

AbstractSince the mid-1980s there have been increasing reports of severe community-acquired pyogenic liver abscess, meningitis and bloodstream infections caused by hypervirulentKlebsiella pneumoniae, predominantly encompassing clonal group (CG) 23 serotype K1 strains. Common features of CG23 include a virulence plasmid associated with iron scavenging and hypermucoidy, and a chromosomal integrative and conjugative element (ICE) encoding the siderophore yersiniabactin and the genotoxin colibactin. Here we investigate the evolutionary history and genomic diversity of CG23 based on comparative analysis of 98 genomes. Contrary to previous reports with more limited samples, we show that CG23 comprises several deep branching sublineages dating back to the 1870s, many of which are associated with distinct chromosomal insertions of ICEs encoding yersiniabactin. We find that most liver abscess isolates (>80%) belong to a dominant sublineage, CG23-I, which emerged in the 1920s following acquisition of ICEKp10(encoding colibactin in addition to yersiniabactin) and has undergone clonal expansion and global dissemination within the human population. The unique genomic feature of CG23-I is the production of colibactin, which has been reported previously as a promoter of gut colonisation and dissemination to the liver and brain in a mouse model of CG23K. pneumoniaeinfection, and has been linked to colorectal cancer. We also identify an antibiotic-resistant subclade of CG23-I associated with sexually-transmitted infections in horses dating back to the 1980s. These data show that hypervirulent CG23K. pneumoniaewas circulating in humans for decades before the liver abscess epidemic was first recognised, and has the capacity to acquire and maintain AMR plasmids. These data provide a framework for future epidemiological and experimental studies of hypervirulentK. pneumoniae. To further support such studies we present an open access and completely sequenced human liver abscess isolate, SGH10, which is typical of the globally disseminated CG23-I sublineage.
Simplifying humanitarian assistance/disaster relief analytic models using activity-based intelligence
Authors: Widener Donald V. , Mazzuchi Thomas A. , Sarkani Shahram 
Published: December 2017

Purpose
The purpose of this paper is to propose an effective knowledge elicitation method and representation scheme that empowers humanitarian assistance/disaster relief (HA/DR) analysts and experts to create analytic models without the aid of data scientists and methodologists while addressing the issues of complexity, collaboration, and emerging technology across a diverse global network of HA/DR organizations.

Design/methodology/approach
The paper used a mixed-methods research approach, with qualitative research and analysis to select the model elicitation method, followed by quantitative data collection and evaluation to test the representation scheme. A simplified analytic modeling approach was created based on emerging activity-based intelligence (ABI) analytic methods.

Findings
Using open source data on the Syrian humanitarian crisis as the reference mission, ABI analytic models were proven capable in modeling HA/DR scenarios of physical systems, nonphysical systems, and thinking.

Practical implications
As a data-agnostic approach to develop object and network knowledge, ABI aligns with the objectives of modeling within multiple HA/DR organizations.

Originality/value
Using an analytic method as the basis for model creation allows for immediate adoption by analysts and removes the need for data scientists and methodologists in the elicitation phase. Applying this highly effective cross-domain ABI data fusion technique should also supplant the accuracy weaknesses created by traditional simplified analytic models.
The value of formal titles to land in residential property transactions
Authors: Alananga Sanga Samwel 
Published: December 2017

Purpose
The purpose of this paper is to analyse the impact of title risks on property prices to establish the associated title risk-price premiums across property types and the moderating effect of occupation strategies for informal transactions.

Design/methodology/approach
Based on household survey data on transactions for 1,514 residential properties in Kinondoni Municipality, Tanzania, binomial logistic regression models were implemented to predict pre-purchase transaction risks. The results of which were used as inputs in mixed effect models to examine the effect of the predicted title risks on (2,010 constant) purchase price for three-bedrooms finished and unfinished housing units and 400 m2 plots.

Findings
Although legal titles have positive overall title risk-price premiums, such premiums hardly accrue from transactions involving finished houses and marginally accrue from vacant plots transactions. On average, unfinished housing purchasers are title risk-averse, “vacant plots” purchasers are title risk-neutral, while “finished housing” purchasers are title risk-lovers.

Research limitations/implications
The sample composition does not include developer-built housing units, the inclusion of which may sway results away from the observations of this study.

Practical implications
Titling alone can hardly be used as a property market stimuli (eliminate transaction risks) unless the market is dominated by unfinished houses.

Originality/value
Existing studies consider neither traded housing products nor pre-purchase transaction risks or consider only one of the two, thus leaving a gap in the literature for which this study sought to bridge. Researchers must incorporate both to arrive at a well-informed conclusion on the potential risks as well as prices achievable in each transaction.
Salesperson performance: role of perceived overqualification and organization type
Authors: Purohit Basant 
Published: December 2017

Purpose
The purpose of this paper is to examine the impact of perceived overqualification (POQ) on salesperson performance.

Design/methodology/approach
In total, 120 usable samples were collected from surveying sales representatives and their sales supervisors from 48 different Indian pharmaceutical firms.

Findings
The results indicated that sales personnel with POQ perform well: in prospector and analyzer type organizations as compared to in defender and reactor type organizations, and when controlled by the outcome-based control system than when controlled by the behavior-based control system.

Practical implications
This study suggests that “person-job” fit criteria used in personnel selection should also consider environmental variables (organization type and control mechanisms) for better job outcomes. The results of the study would enable an organization to assess whether its reward systems and levels are getting the desired impact from sales personnel with different levels of POQ in terms of salesperson performance.

Originality/value
Using “person-job” fit theory, this study examined the role of organization type and sales force control system as moderators of “POQ – Salesperson Performance” relationships and explains how organizations can benefit from enhancing sales performance of salespersons with POQ.