bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual Expression of Nursing Home Residents: Systematic Review of the Literature
Authors: Aguilar Rodolfo A. 
Published: September 2017

AbstractPurposeLiving longer, baby boomers will need specialized care offered by nursing homes to manage chronic conditions. This review explores the knowledge, attitudes, and experiences towards older people's sexuality and sexual expression in nursing homes—an important area of research to meet the needs of this emerging population.DesignA primary search of the Cumulative Index to Nursing and Allied Health Literature (CINAHL) and PubMed databases and secondary inclusion of cited references covering the period January 2000 to November 2016 identified 12 relevant studies.MethodsUsing the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) flow diagram of the screening process, data were extracted, summarized, and compared, and risk of bias was assessed focusing on ethical considerations, sample size and sampling methods, validity and reliability of data collection instruments, participation, cooperation, and response rate.FindingsOverall, sexual expression in older adults is recognized as a basic need that should be supported. Positive attitudes towards sexuality in nursing homes were correlated with a higher level of knowledge about older adults’ sexuality. In addition, positive predictors of attitudes towards sexuality in nursing homes were found to be: age, level of education, and years of experience. Barriers to addressing sexuality in the elderly are the lack of privacy and staff discomfort, which together represent common causes for loneliness and lack of intimacy in nursing homes.ConclusionsNursing research and practice need to shift their focus towards individual needs of nursing home residents to accommodate their values and expectations.Clinical RelevanceCare providers must include a thorough assessment of sexual health of older adults living in nursing homes in routine practice, and include sexual health in the treatment plan.
Managing Persistent Tensions on the Frontline: A Configurational Perspective on Ambidexterity
Authors: Zimmermann Alexander , Raisch Sebastian , Cardinal Laura B. 
Published: September 2017

AbstractAmbidexterity research has noted that firms’ simultaneous pursuit of exploration and exploitation causes organizational tensions that are difficult to resolve. To make these tensions manageable, scholars have generally suggested that senior managers take the central role in designing organizational solutions, such as the structural separation or contextual integration of the exploratory and exploitative tasks. Yet, in an inductive study of ten corporate innovation initiatives, we find that our informants assigned far less importance to the senior managers’ initial design choices than to the frontline managers’ subsequent configurational practices. Frontline managers used these practices to constantly adapt and align their initiatives’ organizational contexts, which allowed them to cope with persistent exploration‐exploitation tensions in their daily business activities. Based on these empirical insights and drawing on paradox theory, we develop a configurational perspective on ambidexterity, where frontline managers play a more central, proactive, and strategic role than purported by the established design perspective on ambidexterity.
Preventive dental care among Medicaid‐enrolled senior adults: from community to nursing facility residence
Authors: Kelly Mary C. , Caplan Daniel J. , Bern‐Klug Mercedes , Cowen Howard J. , Cunningham‐Ford Marsha A. , Marchini Leonardo , Momany Elizabeth T. 
Published: September 2017

AbstractObjectiveThe primary objective of this study was to determine whether the utilization rate of preventive oral health care services while senior adults were community‐dwelling differed from the rate after those same senior adults were admitted to nursing facilities. A secondary objective was to evaluate other significant predictors of receipt of preventive oral health procedures after nursing facility entry.MethodsIowa Medicaid claims from 2007–2014 were accessed for adults who were 68+ years upon entry to a nursing facility and continuously enrolled in Medicaid for at least three years before and at least two years after admission (n = 874). Univariate, bivariate and multivariable analyses were conducted.ResultsDuring the five years that subjects were followed, 52.8% never received a dental exam and 75.9% never received a dental hygiene procedure. More Medicaid‐enrolled senior adults received ≥1 preventive dental procedure in the two years while residing in a nursing facility compared to the three years before entry. In multivariable analyses, the strongest predictor of preventive oral health care utilization after entry was the receipt of preventive oral health services before entry (p < 0.01).ConclusionsThe strongest predictor of receipt of dental procedures in the two years after nursing facility entry was the receipt of dental procedures in the three years before entry while community‐dwelling. This underscores the importance of the senior adult establishing a source of dental care while community‐dwelling.
Long‐Term Follow‐Up of Lymphatic Malformations in Children Treated with Sildenafil
Authors: Tu Joanna H. , Tafoya Elidia , Jeng Michael , Teng Joyce M. 
Published: September 2017

AbstractBackground/ObjectivesLymphatic malformations (LMs) are challenging to treat. Reports on the benefits of sildenafil for LM management have been mixed. This study evaluated long‐term clinical outcomes of pediatric LM patients after sildenafil treatment.MethodsA retrospective chart review was performed on pediatric LM patients treated with sildenafil in the past 5 years. Patients were also contacted to complete a survey of comprehensive questions about their LM after sildenafil and subsequent interventions.ResultsOf 12 patients identified, 10 (83.3%) participated in the follow‐up survey. The average age was 8 years (range 4–16 yrs), median treatment duration was 9 months, and the average time of follow‐up after sildenafil was 4 years; one patient is still taking sildenafil. Ten patients surveyed (83.3%) reported positive therapeutic response, with improvement in the size and compressibility of their LM during posttreatment clinical visits. Six received additional interventions (four sirolimus, one sclerotherapy, one surgery) after sildenafil was discontinued, with all but one reporting a positive response to subsequent interventions. Minor side effects at the time of sildenafil treatment included mild flushing, dizziness, and transient nausea, but no adverse effects were reported at the long‐term follow‐up.ConclusionThis is the first report of long‐term follow‐up of pediatric LM patients treated with sildenafil. Our findings suggest that sildenafil is beneficial for the symptomatic treatment of LMs. Additional analysis on the role of sildenafil as adjuvant therapy is necessary to optimize the use of this medication in the management of complex LMs.
Post‐Chikungunya Rheumatic Disease in a 13‐Year‐Old Boy
Authors: Landis Erin T. , Strowd Lindsay C. , Taxter Alysha J. 
Published: September 2017

AbstractChikungunya is a mosquito‐borne viral infection that causes an acute febrile illness and can result in acute or chronic musculoskeletal disease. A 13‐year‐old boy presented with post‐Chikungunya rheumatic disease featuring connective tissue disease signs including digital ulcerations, cuticular dystrophy, dilated capillary loops, and digital tapering.
Beyond regulatory capture: Coproducing expertise for critical infrastructure protection
Authors: Slayton Rebecca , Clark‐Ginsberg Aaron 
Published: September 2017

AbstractComplex industries such as petroleum production, civil aviation, and nuclear power produce “public risks” that are widely distributed and temporally remote, and thus tend to be ignored by the risk producers. Regulation is perhaps the most common policy tool for governing such risks, but requires expert knowledge that often resides solely within the industries. Hence, many scholars and policymakers raise concerns about “regulatory capture,” wherein regulation serves private interests rather than the public good. This paper argues that regulatory capture framing has tended to limit understanding of expertise and its role in governing public risks. Most studies of regulatory capture treat expertise as a source of knowledge and skills that are created exogenously to political processes, and which can therefore be politically neutral. By contrast, we draw on work in science and technology studies that highlight the value‐laden and relational nature of knowledge and expertise, showing how its formation is endogenous to political processes. Thus, we argue for both broadening analyses of regulatory capture to consider the historically contingent and uncertain process of creating expert knowledge, and going beyond the capture framing by considering the challenge of negotiating different epistemologies and ways of life. We illustrate this analytic strategy by examining the history of and current debate about critical infrastructure protection standards to protect the United States electric power grid from cyberattack. We conclude by considering the broader implications of these findings for governing public risks.
Supporting spirituality in the care of older people living with dementia: a hermeneutic phenomenological inquiry into nurses’ experiences
Authors: Toivonen Kristiina , Charalambous Andreas , Suhonen Riitta 
Published: September 2017

BackgroundSpirituality is defined as a search for answers to existential questions about the meaning of life and the individual's relationship with the sacred or transcendent. This relationship may or may not involve affiliation with a specific religion. Studies on spirituality have focused on palliative care, and there are limited studies into the spirituality in the care of older people with dementia.AimTo describe the experiences of nurses supporting spirituality in the care of older people living with dementia.MethodThis study, informed by Heideggerian hermeneutic phenomenology, was conducted in 2014/15. Data were collected by interviewing a purposive sample of 17 nurses.ResultsSupporting the spirituality of older people with dementia was seen as understanding their spirituality within a framework of person‐centeredness and individuality. The participants came to understand the spiritual needs of older people with dementia through both verbal and nonverbal expression and by learning about older people's individual spiritual backgrounds. Meeting spiritual needs meant approaching the person with dementia as a valuable human as well as paying attention, to and supporting, his/her personal philosophy of life within nursing care.ConclusionLearning and developing an understanding of the spiritual needs of older people with dementia is challenging. The nurses offered person‐centred, spiritual care, to people with dementia from a variety of perspectives, which is important in the provision of comprehensive care. There is a need to find usable tools to help nurses to learn and understand the individual spiritual needs of older people with dementia and to explore how these older adults experience having their spirituality supported within their nursing care.
Genome Sequence of an Unusual Reassortant H1N1 Swine Influenza Virus Isolated from a Pig in Russia, 2016
Authors: Sobolev Ivan , Kurskaya Olga , Murashkina Tatyana , Leonov Sergey , Sharshov Kirill , Kabilov Marsel , Alikina Tatyana , Tolstykh Natalia , Gorodov Vladimir , Alekseev Alexander , Shestopalov Alexander 
Published: September 2017

ABSTRACT
We report here the genome sequence of the influenza A virus strain A/swine/Siberia/1sw/2016, isolated from a swine in Russia. On the basis of sequence analysis, A/swine/Siberia/1sw/2016 is characterized by unusual surface glycoproteins phylogenetically distinct from those of swine A(H1N1)pdm09 influenza virus.
Draft Genome Sequence of Natranaerobius trueperi DSM 18760
T
, an Anaerobic, Halophilic, Alkaliphilic, Thermotolerant Bacterium Isolated from a Soda Lake
Authors: Guo Xiaomeng , Liao Ziya , Holtzapple Mark , Hu Qingping , Zhao Baisuo 
Published: September 2017

ABSTRACT

The anaerobic, halophilic, alkaliphilic, thermotolerant bacterium
Natranaerobius trueperi
was isolated from a soda lake in Wadi An Natrun, Egypt. It grows optimally at 3.7 M Na
+
, pH 9.5, and 43°C. The draft genome consists of 2.63 Mb and is composed of 2,681 predicted genes. Genomic analysis showed that various genes are potentially involved in the adaptation mechanisms for osmotic stress, pH homeostasis, and high temperatures.
First Complete Genome Sequences of Xanthomonas citri pv. vignicola Strains CFBP7111, CFBP7112, and CFBP7113 Obtained Using Long-Read Technology
Authors: Ruh Mylène , Briand Martial , Bonneau Sophie , Jacques Marie-Agnès , Chen Nicolas W. G. 
Published: September 2017

ABSTRACT

Xanthomonas citri
pv. vignicola strains cause bacterial blight of the legume crop cowpea. We report whole-genome sequences of three
X. citri
pv. vignicola strains obtained using PacBio single-molecule real-time sequencing. Such genomic data provide new information on pathogenicity factors, such as transcription activator-like effectors.
Insights into the Draft Genome Sequence of a Haitian Variant Vibrio cholerae Strain Isolated from a Clinical Setting in Kerala, South India
Authors: Narendrakumar Lekshmi , Suryaletha Karthika , Reghunathan Dinesh , Prasannakumar Manoj , Thomas Sabu 
Published: September 2017

ABSTRACT

We report here the draft genome sequence of a Haitian variant
Vibrio cholerae
strain, W4-13, isolated from Kerala, South India, possessing cholera toxin gene in chromosomes I and II. The sequence will be useful to achieve a profound understanding on its evolution, with emphasis on its pathogenesis and antibiotic resistance.
Draft Genome Sequence of the Gluten-Hydrolyzing Bacterium Bacillus subtilis GS 188, Isolated from Wheat Sourdough
Authors: Rashmi B. S. , Gayathri Devaraja 
Published: September 2017

ABSTRACT

The draft genome sequence of
Bacillus subtilis
GS 188, a novel spore-forming probiotic bacterium with gluten-hydrolyzing potential, was isolated from wheat sourdough and provides deep insights into the beneficial features of this strain for its use in the preparation of gluten-reduced wheat foods for humans with celiac disease.
Complete Genome Sequence of Staphylococcus epidermidis ATCC 12228 Chromosome and Plasmids, Generated by Long-Read Sequencing
Authors: MacLea Kyle S. , Trachtenberg Ariel M. 
Published: September 2017

ABSTRACT

Staphylococcus epidermidis
ATCC 12228 was sequenced using a long-read method to generate a complete genome sequence, including some plasmid sequences. Some differences from the previously generated short-read sequence of this nonpathogenic and non-biofilm-forming strain were noted. The assembly size was 2,570,371 bp with a total G+C% content of 32.08%.
Basic Processes in
Salmonella
-Host Interactions: Within-Host Evolution and the Transmission of the Virulent Genotype
Authors: Diard Médéric , Hardt Wolf-Dietrich 
Published: September 2017

ABSTRACT

Transmission and virulence are central aspects of pathogen evolution. However, in many cases their interconnection has proven difficult to assess by experimentation. Here we discuss recent advances from a mouse model for
Salmonella
diarrhea. Mouse models mimic the enhanced susceptibility of antibiotic-treated individuals to nontyphoidal salmonellosis. In streptomycin-pretreated mice,
Salmonella enterica
subspecies 1 serovar Typhimurium efficiently colonizes the gut lumen and elicits pronounced enteropathy. In the host’s gut,
S.
Typhimurium forms two subpopulations that cooperate to elicit disease and optimize transmission. The disease-causing subpopulation expresses a set of dedicated virulence factors (the type 3 secretion system 1 [TTSS-1]) that drive gut tissue invasion. The virulence factor expression is “costly” by retarding the growth rate and exposing the pathogen to innate immune defenses within the gut tissue. These costs are compensated by the gut inflammation (a “public good”) that is induced by the invading subpopulation. The inflamed gut lumen fuels
S.
Typhimurium growth, in particular that of the TTSS-1 “off” subpopulation. The latter grows up to very high densities and promotes transmission. Thus, both phenotypes cooperate to elicit disease and ensure transmission. This system has provided an experimental framework for studying within-host evolution of pathogen virulence, how cooperative virulence is stabilized, and how environmental changes (e.g., antibiotic therapy) affect the transmission of the virulent genotype.
Follow-up after gestational diabetes: a fixable gap in women’s preventive healthcare
Authors: Bernstein Judith Apt , Quinn Emily , Ameli Omid , Craig Myrita , Heeren Timothy , Lee-Parritz Aviva , Iverson Ronald , Jack Brian , McCloskey Lois 
Published: September 2017

ObjectiveGestational diabetes mellitus (GDM) is a known harbinger of future type 2 diabetes mellitus (T2DM), hypertension, and cardiac disease. This population-based study was designed to identify gaps in follow-up care relevant to prevention of T2DM in a continuously insured sample of women diagnosed with GDM.Research design and methodsWe analyzed data spanning 2005–2015 from OptumLabs Data Warehouse, a comprehensive, longitudinal, real-world data asset with deidentified lives across claims and clinical information, to describe patterns of preventive care after GDM. Women with GDM were followed, from 1 year preconception through 3 years postdelivery to identify individual and healthcare systems characteristics, and report on GDM-related outcomes: postpartum glucose testing, transition to primary care for monitoring, GDM recurrence, and T2DM onset.ResultsAmong 12 622 women with GDM, we found low rates of glucose monitoring in the recommended postpartum period (5.8%), at 1 year (21.8%), and at 3 years (51%). A minority had contact with primary care postdelivery (5.7% at 6 months, 13.2% at 1 year, 40.5% at 3 years). Despite increased population risk (GDM recurrence in 52.2% of repeat pregnancies, T2DM onset within 3 years in 7.6% of the sample), 70.1% of GDM-diagnosed women had neither glucose testing nor a primary care visit at 1 year and 32.7% had neither at 3 years.ConclusionsWe found low rates of glucose testing and transition to primary care in this group of continuously insured women with GDM. Despite continuous insurance coverage, many women with a pregnancy complication that portends risk for future chronic illness fail to obtain follow-up testing and may have difficulty navigating between clinician specialties. Results point to a need for action to close the gap between obstetrics and primary care to ensure receipt of preventive monitoring as recommended by both the American Diabetes Association and the American Congress of Obstetricians and Gynecologists.
Engaging patients through an iBooks-based patient portal tutorial
Authors: Leisy Heather , Ahmad Meleha , Guevara Gabriella , Smith Roland Theodore 
Published: September 2017

IntroductionPatient portals or personal health records allow patients to access their health information and communicate with their physician’s office outside of their clinic visit. As such, their use has been observed to increase patient engagement and decrease administrative costs. Despite these advantages, patient adoption and successful use of patient portals remains low. Here we assess the feasibility and efficacy of an iBooks-based tutorial in increasing comfort and compliance with personal health record use.MethodsWe created and published a 5-min iBooks-based tutorial describing our institution’s patient portal features. We administered the tutorial, along with presurvey and postsurvey, to ophthalmology clinic patients.ResultsOf 70 participants, 50% had already registered for our institution’s patient portal. Registered patients had viewed labs (74%, n=26) and messaged providers (57%, n=20) but rarely used other features such as scheduling appointments (17%, n=6) or requesting refills (26%, n=9). After the tutorial, comfort levels in knowledge on how to use portal features increased by 20%–80%, depending on portal feature and registration status. Main barriers to portal usage were preference for telephone-based communication (26%, n=18) and knowledge of portal existence (21%, n=15). The majority (86%, n=60) agreed the tutorial would increase their utilisation of the patient portal.ConclusionTutorials increase knowledge and awareness of patient portal features, allowing these features to be fully used. An iBooks-based approach allows patients to successfully access and use tutorial content outside of the clinic.
Hospital comparison of stroke care in Sweden: a register-based study
Authors: Lekander Ingrid , Willers Carl , Ekstrand Elisabeth , von Euler Mia , Fagervall-Yttling Birgitta , Henricson Lena , Kostulas Konstantinos , Lilja Mikael , Sunnerhagen Katharina S , Teichert Jörg , Pessah-Rasmussen Hélène 
Published: September 2017

Background and purposeThe objective of this study was to estimate the level of health outcomes and resource use at a hospital level during the first year after a stroke, and to identify any potential differences between hospitals after adjusting for patient characteristics (case mix).MethodData from several registries were linked on individual level: seven regional patient administrative systems, Swedish Stroke Register, Statistics Sweden, National Board of Health and Welfare and Swedish Social Insurance Agency. The study population consisted of 14 125 patients presenting with a stroke during 2010. Case-mix adjusted analysis of hospital differences was made on five aspects of health outcomes and resource use, 1 year post-stroke.ResultsThe results indicated that 26% of patients had died within a year of their stroke. Among those who survived, almost 5% had a recurrent stroke and 40% were left with a disability. On average, the patients had 22 inpatient days and 23 outpatient visits, and 13% had moved into special housing. There were significant variations between hospitals in levels of health outcomes achieved and resources used after adjusting for case mix.ConclusionDifferences in health outcomes and resource use between hospitals were substantial and not entirely explained by differences in patient mix, indicating tendencies of unequal stroke care in Sweden. Healthcare organisation of regions and other structural features could potentially explain parts of the differences identified.