bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between core competence and perceived professional benefits among oncology specialist nurses: A cross‐sectional study
Authors: Li Zhen , Wang Lingmin 
Published: September 2024

AbstractAimTo investigate the current state and influencing factors of core competence of oncology specialist nurses as well as the relationship between core competence and perceived professional benefits.DesignA cross‐sectional correlational survey.MethodsThis questionnaire survey was conducted with oncology specialist nurses working in a Grade III A (tertiary) Public Cancer Hospital in Jinan, China in March 2021. Based on informed consent, a convenience sampling of 350 nurses participated in the study, with 322 valid questionnaires collected. Using IBM SPSS21.0, the data were analysed to perform descriptive statistics, analysis of variance (ANOVA), multiple stepwise regression analysis and Pearson's correlation analysis.ResultsThe overall average score of nurses' core competence was 224.28 ± 7.95, a medium level and the overall average score of their perceived professional benefits was 132.99 ± 5.05. Nurses' core competence was positively correlated with perceived professional benefits. The differences in professional title, education, working years and perceived professional benefits were statistically significant.ConclusionThe findings indicated that nurses' perceived professional benefit is an important factor affecting core competence. Nursing managers who take main responsibility for the quality of care should adopt measures to increase perceived professional benefits, which not only promote nurses' job satisfaction and happiness, but also enhance the development of their core competence and the quality of cancer care as well.Patient or Public ContributionAll participants contributed to the conducting of this study by completing self‐reported questionnaires.
Evaluating the Impact of Gender and Race on Otolaryngology Resident Experiences Across the United States
Authors: Lodha Shweta , Luzum Nathan , Washabaugh Claire , Allen Ariana , Stinnett Sandra , Woodard Charles , Fekrat Sharon 
Published: September 2024

AbstractObjectiveOtolaryngology residents often encounter work‐related stress and challenges during training. Sociodemographic factors influence experiences during residency; however, the impact of race and gender on otolaryngology trainee well‐being during residency remains understudied.Study DesignOnline survey.SettingUS residency programs.MethodsAn anonymous online survey consisting of 59 multiple‐choice questions was sent to 104 directors of Accreditation Council for Graduate Medical Education otolaryngology residency programs to distribute to residents. Respondents were queried regarding demographics and experiences with bias. Residents self‐identified gender and race. Black, Hispanic/Latinx, Middle Eastern/North African, and multiracial residents were categorized as underrepresented minorities (URM).ResultsSixty‐one US otolaryngology residents responded to the survey, the majority of whom were women (60.7%) and white (62%). Many residents endorsed a belief that receipt of research and training opportunities was negatively impacted by bias due to race (29.5%) or gender (45.9%). More women (27%) than men (13%) reported maximal burnout, and fewer men (17.4%) than women (40.5%) expressed low confidence in ability to independently care for patients. More male (47.8%) and white (31.6%) residents strongly agreed they were thriving. 94.6% of women and 33.3% of URM residents reported being mistaken for a nonphysician, compared to 0% of white male respondents.ConclusionOtolaryngology residents perceived differential treatment based on race and gender, with women and URM residents experiencing greater exclusion and bias, as well as increased misidentification and decreased ability to thrive. Future work includes increasing sample size for generalizability and developing interventions that uphold equity in residency training environments.
Common progenitor origin for Rosai–Dorfman disease and clear cell sarcoma
Authors: Sato Aki , Yusa Nozomi , Takamori Hiroyuki , Shimizu Eigo , Yokoyama Kazuaki , Ichikawa Satoshi , Yokoyama Hisayuki , Kasahara Yuki , Enda Kodai , Fujishima Fumiyoshi , Ichinohasama Ryo , Ota Yasunori , Imoto Seiya , Nannya Yasuhito 
Published: September 2024

AbstractHistiocytic neoplasms (HNs) in adults have been reported to be associated with a high prevalence of coexisting haematological and solid malignancies. While a proportion of coexisting HNs and haematological malignancies share identical genetic alterations, the genetic association between HNs and solid malignancies has scarcely been reported. We report a case of Rosai–Dorfman disease (RDD) complicated by coexisting clear cell sarcoma (CCS). RDD is a rare HN. CCS is an ultrarare soft tissue sarcoma with a poor prognosis. Mutation analysis with whole‐exome sequencing revealed six shared somatic alterations including NRAS p.G12S and TP53 c.559+1G>A in both the RDD and CCS tissue. This is the first evidence of a clonal relationship between RDD and solid malignancies using mutational analysis. We hypothesise that neural crest cells, which originate in CCS, are likely the common cells of origin for RDD and CCS. This case helps to unravel the underlying clinicopathological mechanisms of increased association of solid malignancies in HNs. © 2024 The Author(s). The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
Low velocity impact study of vacuum bag infused bouligand inspired composites
Authors: Amorim L. , Santos A. , Nunes J. P. , Viana J. C. 
Published: September 2024

AbstractThis work proposes three Bouligand‐inspired layups to enhance low velocity impact (LVI) damage resistance and tolerance of convectional aircraft composite laminates. Two Bouligand‐like (HL and HL_S) and one hybrid design layup, merging conventional and Bouligand architecture (HYB), were produced by vacuum bag infusion. Their performance under LVI, at 13.5, 25 and 40 (J), and compression after impact (CAI) tests were evaluated and compared with a conventional aircraft multidirectional layup (LS) produced under identical conditions. Results demonstrated that, especially for the higher impact energy levels, both Bouligand‐like laminates consistently outperformed all the other configurations, exhibiting higher load bearing capacity (peak load) and energy absorption. Additionally, the rough and poorly defined interlaminar region of Bouligand‐like layups have showed to delay severe damage for higher loads and energies, dissipating all (at 13.5 J) or most of the impact energy (more than 50%) through subcritical damage mechanisms. Compared with LS laminate, Bouligand‐inspired layups postponed the onset of severe damage thresholds by up to 120% in load and 66% in energy (HL laminate) while developing smaller and more localized damages. The high number of fibers aligned in the loading direction of LS laminate led to better damage tolerance.Highlights
Vacuum bag infused Bouligand‐like laminates consistently demonstrated superior performance than the conventional aircraft multidirectional layup, exhibiting higher load bearing capacity and energy absorption, particularly at higher impact energy levels;
The rough and poorly defined interlaminar region observed in both Bouligand‐like layups demonstrated to play an essential role in the efficiency of damage mechanisms, dissipating all (at low impact energy levels) or more than 50% of impact energy on subcritical damages, such as translaminar matrix cracking;
Compared with the conventional layup, HL Bouligand‐like laminate postponed 120% and 66% load and energy severe damage onset thresholds;
The high number of fibers aligned in the loading direction of LS laminate led to better damage tolerance, despite the larger damaged areas observed.
Vibration analysis of functionally graded carbon nanotube‐reinforced composite open cylindrical shells with damping film embedded
Authors: Zhai Yanchun , Li Feng , Wang Xiaoying , Qiao Huaying , Wan Zhiyuan , Zhou Yuesong 
Published: September 2024

AbstractIn the present study, a discrete layer model was established to explore the vibration performance of Functionally Graded Carbon Nanotube‐Reinforced Composite (FG‐CNTRC) open cylindrical shells with damping film embedded based on the first‐order shell theory. There are four configurations of stacking arrangements considered for FG‐CNTRC open cylindrical shells with damping film embedded. The equivalent structural parameters of the top and bottom FG‐CNTRC panels are generated by implementing the extended mixing rule. Governing equations are derived based on the Hamilton principle and solved with the Naiver solution. Subsequently, after verifying the validity of this paper's solution by comparing it with the published literature, a parametric elaborated investigation discloses the variation patterns of vibration performance of four FG‐CNTRC open cylindrical shells with damping film embedded. The conclusions of the study can be used as a useful guide about open cylindrical composite shell structures with the design of high strength and damping.Highlights
Discrete layer vibration model was bulit based on first‐order shell theory.
Vbration performance of FG‐CNTRC open sandwich shells was studied.
Variation patterns of frequency and loss factor was disclosed.
Isotope‐Tracing for Conceptual Model Formation During the Holocene of Eletsky Palsa, Bolshezemelskaya Tundra
Authors: Vasil'chuk Yurij K. , Budantseva Nadine A. , Vasil'chuk Alla C. , Chizhova Julia N. , Vasil'chuk Jessica Yu. , Ginzburg Alexander P. 
Published: September 2024

ABSTRACTStudies of permafrost agradation within peat mires leading to palsa growth and palsa dynamics during the Holocene are important for predicting the future of permafrost in a changing climate. The radiocarbon age of peat cover and stable isotope composition of the ice cores of palsas near Eletsky settlement, north‐east of the European part of Russia, were studied. Palsa growth was the most active between 8 and 5 cal ka BP. The main sources for ice core formation were precipitation‐fed surface and suprapermafrost waters. It is assumed that the isotope composition of the initial water was isotopically depleted compared with modern surface waters, which may be explained by general climate cooling during earlier stages of palsa growth (response to the 8.2 ka cooling event). The ice cores of the studied palsas were formed during the freezing of water in semi‐closed conditions, mainly by the segregation mechanism during permafrost agradation, thickness of the ice lenses and ice volume could depend on freezing rates and water supply. The upper part of the palsa ice core experienced deep thawing and could be saturated with meteoric water; repeated freezing of this part of the ice core likely occurred in closed system conditions.
Advances in InSAR Analysis of Permafrost Terrain
Authors: Zwieback S. , Liu L. , Rouyet L. , Short N. , Strozzi T. 
Published: September 2024

ABSTRACTDifferential interferometric synthetic aperture radar (InSAR) is a remote sensing technique for measuring surface displacements with precision down to millimeters, most commonly from satellites. In permafrost landscapes, InSAR measurements can provide valuable information on geomorphic processes and hazards, including thaw subsidence and frost heave, thermokarst, and permafrost creep. We first review recent progress in InSAR data availability, InSAR processing and uncertainty analysis methods relevant to permafrost studies. These technical advances have contributed to our understanding of surface deformation in flat and sloping terrain in polar and mountainous regions. We emphasize two emerging trends. First, InSAR increasingly enables insight into the mechanisms, controls, and drivers of permafrost landscape dynamics on subseasonal to decadal time scales. Second, InSAR observations in conjunction with models enable novel ways to infer subsurface parameters, such as near‐surface ground ice content and active layer thickness. We anticipate that in the coming decade, InSAR will mature into a widely used operational tool for monitoring, modeling, and planning across rapidly changing permafrost landscapes.
Exploring the therapeutic implications of natural compounds modulating apoptosis in vascular dementia
Authors: Zhong Guangcheng , Wang Xinyue , Zhang Qian , Zhang Xueying , Fang Xiaoling , Li Shuting , Pan Yaru , Ma Yujie , Wang Xuejing , Wan Ting , Wang Qi 
Published: September 2024

AbstractVascular dementia (VaD) is a prevalent form of dementia stemming from cerebrovascular disease, manifesting in memory impairment and executive dysfunction, thereby imposing a substantial societal burden. Unfortunately, no drugs have been approved for the treatment of VaD due to its intricate pathogenesis, and the development of innovative and efficacious medications is urgently needed. Apoptosis, a programmed cell death process crucial for eliminating damaged or unwanted cells within an organism, assumes pivotal roles in embryonic development and tissue homeostasis maintenance. An increasing body of evidence indicates that apoptosis may significantly influence the onset and progression of VaD, and numerous natural compounds have demonstrated significant therapeutic potential. Here, we discuss the molecular mechanisms underlying apoptosis and its correlation with VaD. We also provide a crucial reference for developing innovative pharmaceuticals by systematically reviewing the latest research progress concerning the neuroprotective effects of natural compounds on VaD by regulating apoptosis. Further high‐quality clinical studies are imperative to firmly ascertain these natural compounds' clinical efficacy and safety profiles in the treatment of VaD.
Organosulfur Compounds, S‐Allyl‐L‐Cysteine and S‐Ethyl‐L‐Cysteine, Target PCSK‐9/LDL‐R‐Axis to Ameliorate Cardiovascular, Hepatic, and Metabolic Changes in High Carbohydrate and High Fat Diet‐Induced Metabolic Syndrome in Rats
Authors: Ahmad Parvej , Shah Arunim , Waiz Mohd , Chaturvedi Chandra P. , Alvi Sahir Sultan , Khan M. Salman 
Published: September 2024

ABSTRACTMetabolic syndrome (MetS) is an ever‐evolving set of diseases that poses a serious health risk in many countries worldwide. Existing evidence illustrates that individuals with MetS have a 30%–40% higher chance of acquiring type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), or both. This study was undertaken to uncover the regulatory role of natural organosulfur compounds (OSCs), S‐allyl‐L‐cysteine (SAC), and S‐ethyl‐L‐cysteine (SEC), in targeting high carbohydrate high fat (HCHF)‐diet‐induced MetS‐associated risk management. Our findings suggested that SAC and SEC ameliorated HCHF‐diet‐induced diabetic profiles, plasma lipid and lipoprotein level, liver function, oxidative‐stress, inflammatory cytokines, and chemokines including monocyte chemoattractant protein‐1 (MCP‐1), lipid peroxidation, plasma proprotein convertase subtilisin/kexin type‐9 (PCSK‐9), and high‐sensitivity C‐reactive protein (hs‐CRP). Moreover, the assessment of the hepatic mRNA expression of the key genes involved in cholesterol homeostasis depicted that SAC and SEC downregulated the PCSK‐9 mRNA expression via targeting the expression of HNF‐1α, a transcriptional activator of PCSK‐9. On the other hand, the LDL‐receptor (LDL‐R) expression was upregulated through the activation of its transcriptional regulator sterol regulatory element binding protein‐2 (SREBP‐2). In addition, the activity and the mRNA expression of 3‐hydroxy‐3‐methylglutaryl coenzyme‐A reductases (HMG‐R) and peroxisome proliferator‐activated receptors (PPARs) were also improved by the treatment of SAC and SEC. We concluded that SAC and SEC can protect against MetS via improving the lipid and lipoprotein content, glycemic indices, hepatic function, targeting the inflammatory cascades, and oxidative imbalance, regulation of the mRNA expression of PCSK‐9, LDL‐R, SREBP‐2, HNF‐1α, PPARs, and inflammatory biomarkers.
Evaluation of orthogonal composite designs for second‐order model in presence of missing observation
Authors: Ezievuo Chibuzo Solomon , Oladugba Abimibola Victoria , Babatunde Oluwagbenga Tobi 
Published: September 2024

AbstractOrthogonal‐array composite designs (OACDs) and orthogonal‐uniform composite designs (OUCDs) are orthogonal composite designs that combine two‐level full or fractional factorial and three‐level orthogonal‐array/uniform designs for estimation of the linear, bilinear, and quadratic effects in a second‐order response surface model. In this study, the effects of missing one observation in the various design portions (factorial (f) axial (a) and center (c)), on the precision of parameter estimates, prediction variance and design efficiency of OACDs and OUCDs for 5 ≤ k ≤ 9 factors at different values of α (the distance of a non‐zero co‐ordinate in an additional design point from the center) are evaluated. The results showed that missing a factorial and an axial point have adverse effect on the precision of parameter estimates of OACDs and OUCDs, while missing a center point has little effect. Missing an axial point caused the highest effect on the prediction variance and design efficiencies. The FDS plots showed OACDs to be better designs for k ≤ 7 and OUCDs for k = 8 and 9 factors.
Assessment of reliability and availability of a system by using a bivariate stochastic model
Authors: Mohsin Muhammad , Bilal Aisha , Ali Zulfiqar 
Published: September 2024

AbstractIn the present age of industrial revolution where the smart manufacturing and smart production are being used in the developed countries, the production systems are still vulnerable to disruptions and outages that affect the reliability and availability of the systems. Certain scientific and probabilistic approaches are required to study the inter‐failure times and repair times and find the possible solutions for maximum production and minimum losses. In this article, we propose a bivariate Power Pareto distribution to model the inter‐failure times and repair times of a system along with some of its characteristics. The model parameters are estimated by employing the maximum likelihood estimation, Bayesian estimation and ant colony optimization algorithm. A simulation study is conducted for different sample sizes to assess the stability of the model parameters. Moreover, we derive the distribution of convolution from our proposed bivariate stochastic distribution and compute its quantiles that help to determine the total time of availability and recovery of a certain system. To demonstrate the efficacy of our model, we use real data set of inter‐failure times and repair times of a certain system.
A seven‐month‐old baby presenting excessive crying for pulmonary sequestration with torsion: A case report and literature review
Authors: Li Li , Wang Yuanxiang , Sun Longwei , Wang Wenjian 
Published: September 2024

AbstractPulmonary sequestration with torsion is a rare condition. We describe a seven‐month‐old baby presenting excessive crying for pulmonary sequestration with torsion. Contrast‐enhanced chest computed tomography demonstrated an oval‐shaped mass in the posteromedial right lower chest, no systemic arterial supply was evident. The edge of the mass showed slight linear reinforcement, and its interior had no reinforcement. Thoracoscopic segmentectomy was carried out and histology confirmed pulmonary sequestration with torsion.
The link between sustainability initiatives at firm and supply chain levels: The mediating role of involvement of partners
Authors: Ramanathan Usha , Ramanathan Ramakrishnan , Balakrishnan A. S. , Hermens Imke 
Published: September 2024

AbstractThe deliberations of the COP28 in Dubai in December 2023 and the growing importance of UN Sustainable Development Goals have highlighted that sustainability initiatives have moved from being ‘nice‐to‐do’ to ‘must‐do’. The resource dependency theory suggests that a firm cannot develop green strategies in isolation, and a substantial involvement of all supply chain partners is needed for achieving larger impacts on environmental sustainability. However, the literature has yet to explore this link in detail. In this paper, we investigate the link between sustainability initiatives at a firm level and at the supply chain level in line with global green agenda. Data collected through a questionnaire survey of senior logistics and supply‐chain managers in UK companies were used to propose and statistically validate a framework combining both constructs and causal hypotheses. We further use a case of a farming company from Luxemburg to validate our research findings. Our results suggest a strong link in terms of green strategies between the firm level and supply chain level. We find that this link is mediated by the degree of involvement of supply chain partners. A case company participated in the study agreed to our research findings related to importance of technology and collaboration in food sector to share the resources among all supply chain players. We also find that green strategies result in improved business performance.
Programming Fast DNA Amplifier Circuits with Versatile Toehold Exchange Pathway
Authors: Mo Fengye , Li Chenbiao , Sun Junlin , Lin Xue , Yu Shuyi , Wang Fuan , Liu Xiaoqing , Li Jinghong 
Published: September 2024

AbstractDNA amplifier circuits establish powerful tools to dynamically control molecular assembly for computation, sensing, and biological applications. However, the slow reaction speed remains a major barrier to their practical utility. Here, diverse fast DNA amplifier circuits termed toehold exchange polymerization (TEP) and toehold exchange catalysis (TEC) using toehold exchange‐mediated assembly as a fundamental mechanism are built. Both TEP and TEC with a duplex and a hairpin can respond within minutes to diverse nucleic acid inputs with high fidelity. In addition, the circuits can amplify live‐cell signals for fluorescence imaging target RNA dynamics and discriminating different cell lines. Compared with existing DNA circuits that involve time scales of hours for transducing small signals, TEP and TEC exhibit much faster dynamics, simpler design, and comparable sensitivity. These features make TEP and TEC promising platforms to develop programmable nucleic acid tools and devices and to create fast sensing and processing systems, amenable to wide practical applications.
Microfluidic Shape Analysis of Non‐spherical Graphite for Li‐Ion Batteries via Viscoelastic Particle Focusing
Authors: Park Jee In , Hong Sabin , Jin Daekwon , Lee Won Jun , Kim Kyeong Jin , Lee Young Ki , Lee Seung Woo , Ahn Kyung Hyun , Hwang Jongkook , Kim Ju Min 
Published: September 2024

AbstractThe size and shape of graphite, which is a popular active anode material for lithium‐ion batteries (LIBs), significantly affect the electrochemical performance of LIBs and the rheological properties of the electrode slurries used in battery manufacturing. However, the accurate characterization of its size and shape remains challenging. In this study, the edge plane of graphite in a cross‐slot microchannel via viscoelastic particle focusing is characterized. It is reported that the graphite particles are aligned in a direction that shows the edge plane by a planar extensional flow field at the stagnation point of the cross‐slot region. Accurate quantification of the edge size and shape for both spheroidized natural and ball‐milled graphite is achieved when aligned in this manner. Ball‐milled graphite has a smaller circularity and higher aspect ratio than natural graphite, indicating a more plate‐like shape. The effects of these differences in graphite shape and size on the rheological properties of the electrode slurry, the structure of the coated electrodes, and electrochemical performance are investigated. This method can contribute to the quality control of graphite for the mass production of LIBs and enhance the electrochemical performance of LIBs.