bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENTRE VIENA E VERONA: uma estratégia para os dois mundos (1815-1822)
Authors: COSTA WILMA PERES 
Published: May 2016

O artigo propõe-se a estudar alguns pontos nodais da chamada ”Era dos Congressos” (1815-1822) para pensar o modo como se reconfiguraram, naquele perá­odo, as relações entre o Velho e o Novo Mundo. Especial atenção é dada á peculiaridade vivida pela América Portuguesa, em razão da presença da Corte no Rio de Janeiro, o que possibilitava alternativas polá­ticas distintas da América Espanhola. No que se refere ao Congresso de Verona, atribuá­mos especial atenção á s negociações referentes ao tráfico negreiro e á consolidação da monarquia constitucional.Palavras-chave: Congresso de Viena. Congresso de Verona. Chateaubriand. Escravidão. Independência. Monarquia Constitucional. BETWEEN VIENNA AND VERONA: one strategy for two worlds (1815-1822) Abstract: The article proposes to study some nodal points of the so called "Age of Congress (1815-1822) to think how is reconfigured, in that period, the relationship between the Old and the New World. Special attention is given to the peculiarity experienced by Portuguese America, due to the Court's presence in Rio de Janeiro, which enabled different policy alternatives from those in Spanish America. With regard to the Congress of Verona, we assign special attention to negotiations regarding slave trade and the strengthening of constitutional monarchy. Keywords: Congress of Vienna. Congress of Verona. Chateaubriand. Slavery. Independence. Constitutional Monarchy. ENTRE VIENA Y VERONA: una estrategia para los dos mundos (1815-1822)Resumen: El artá­culo propone estudiar algunos puntos de la " Era de los Congresos" (1815-1822) para analisar cómo se reconfiguraron en ese perá­odo, las relaciones entre el Antiguo y el Nuevo Mundo. Se presta especial atención a la peculiaridad experimentada por América portuguesa, a causa de la presencia de la Corte, en Rá­o de Janeiro, lo que permitió alternativas polá­ticas distintas de las que experimentadas por América española. A lo que se refiere al Congreso de Verona, atribuimos especial atención a las negociaciones referentes al comercio de esclavos y la consolidación de la monarquá­a constitucional. Palabras clave: Congreso de Viena. Congreso de Verona. Esclavitud. Independencia. Monarquá­a constitucional.
A DIPLOMACIA PORTUGUESA NO CONGRESSO DE VIENA (1815): a trajetória do primeiro Duque de Palmela, D. Pedro de Sousa Holstein
Authors: BASILIO ROMARIO SAMPAIO 
Published: May 2016

PORTUGUESE DIPLOMACY IN THE VIENNA CONGRESS (1815): the trajectory of D. Pedro de Sousa Holstein, first Duke of Palmela LA DIPLOMACIA PORTUGUÉSA EN EL CONGRESO DE VIENA (1815): la trayectoria del primer Duque de Palmela, D. Pedro de Sousa Holstein
Transition from NICU to Home: Are the Parents Ready to Manage Any Emergency? An Evidence-Based Project
Authors: Murray Chantel H. , Joseph Rachel A. 
Published: May 2016

ABSTRACTTransitioning the care of a previously critically ill infant to home poses many challenges for the parents. Prior to the infant’s discharge, the parents undergo rigorous training to continue the care of their infants at home. Even after training, parents may feel overwhelmed by the thought of managing an emergency at home. This evidence-based practice project aims to provide parents with additional hands-on practice of cardiopulmonary resuscitation (CPR) prior to their infant’s discharge. Based on this project, a program of teaching CPR regularly is established currently in the NICU at Nemours Alfred I. duPont Hospital for Children.
Using a Collaborative Process to Develop Goals and Self-Management Interventions to Support Young Adults With Disabilities at Work
Authors: Nittrouer Christine L. , Shogren Karrie A. , Pickens Julie L. 
Published: May 2016

Purpose:This study examined the impact of using a collaborative process with person-centered teams and a functional assessment of problems in the workplace to design individualized goals and self-management interventions to support young adults with disabilities. These young adults had achieved employment through a customized employment process but were beginning to face challenges maintaining and advancing in their job roles.Method:A single subject, multiple baseline study was conducted with three individuals ages 22–29 years with autism and/or intellectual disability to determine the impact of the intervention on on-task behavior and job task completion.Results:The results suggest that the process can lead to meaningful change in the on-task and job completion behavior of young adults with disabilities in inclusive employment settings, although there were limitations.Conclusion:The findings, outcomes, and implications confirm and extend our understanding of the impact of person-centered teams, goal setting, functional assessment, and self-management after young adults with disabilities are employed in community-based settings.
Primary Oral Melanoma – A Non‐Surgical Approach to Treatment via Immunotherapy
Authors: Castaño Alejandro , Shah Sonal S. , Cicero Giuseppe , El Chaar Edgard 
Published: May 2016

Introduction: Malignant melanoma is an aggressive form of cancer that commonly affects skin and rarely affects the oral cavity. With poorly understood risk factors and an often‐asymptomatic presentation, oral melanoma is difficult to detect until advanced stages of disease. Treatment for oral melanomas has been primarily surgical, and survival rates have been low. However, in recent years, immunotherapy has shown much promise with increased patient survival.Case Presentation: A 49‐year‐old male was referred by his primary dentist to a periodontal clinic for management of an alleged unresolved periodontal abscess. The patient had completed full‐mouth scaling and root planing and consequently developed a large mass in the left posterior maxilla. Incisional biopsies were performed in multiple locations in the maxillary gingivae, and interpretation revealed atypical melanocytic proliferation and primary melanoma. After appropriate work‐up, the patient was treated with two different immunotherapy agents: 1) ipilimumab and 2) pembrolizumab. Results after immunotherapy were favorable, and the tumor significantly decreased in size with no major adverse effects. The response was so strikingly positive that the need for surgical removal was almost eliminated. At the present time, it is unknown whether the patient will receive any surgical treatment barring a recurrence.Conclusions: Oral mucosal pigmentation is a finding commonly encountered by dentists during clinical patient examinations. However, proper diagnosis of pigmented lesions, especially those associated with malignancy, requires investigations that go beyond clinical examination.
Physical Damages of Wood Fiber in Acacia Mangium due to Biopulping Treatment
Authors: Yahya Ridwan , Mucharromah Mucharromah , Silsia Devi , Septiana Septiana 
Published: May 2016

Biopulping is fungal pretreatment of wood chips to reduce unused chemical composition of material in pulping. Preliminary study showed that pretreatment of Phanerochaetachrysosporium to Acacia mangium Willd can reduce lignin and improve holocellulose and cellulose content of the material. Fiber dimension recognized as other important factor for paper properties. The question is how the integrity and dimensions of the wood fiber that has been pretreated with the fungus. The objectives of present study were to know effect of pretreatment of P. chrysosporium to the integrity and dimensions of the fiber. The P. chrysosporium was cultured for 14 days in growth medium, and inoculated to wood chips 5% (w/v) and incubated for 0, 15 and 30 days. The inoculated wood chips were chipped into 1 mm x 1 mm x 20 mm and macerated using franklin solution at 60 oC for 48 hours. Forty fibers from each incubated time were analized their physical damages using a light microscope at a 400 magnification. The inoculated fibers were measured theirs dimensions. The physical damage percentage of fibers pretreated using P. chrysosporium was 0%. Length and wall thickness of the pretreated fibers were can be categorized as middle class and thin fibers, respectively.
L'église de Beauval et la famille Saint.
Authors: Lefebvre François 
Published: May 2016

Der kerk van Beauval en de famille Saint.
De gebroeders Saint, afkomstig uit Beauval in de Somme, hebben bijgedragen tot de opgang van de Franse juteindustrie in de eerste helft van de XlXde eeuw, Hun nakomelingen hebben, vooral in het departement van de Somme, van 1857 tot in dejaren 1890, een machtig industrieel bedrijf opgebouwd, dat een nationale dimensie heeft. Zij waren bewust van hun patronale verplichtin- gen en bezorgd om het welzijn van hun arbeiders, als vele industriëlen toen, en de leiders van Saint Frères, en vooral een ervan, Charles Saint (1826-1902) heeft een reeks sociale verwezenlijkingen tot stand gebracht. De kerk van Beauval, aangekocht in 1888, op kosten van de familie Saint, sluit die reeks af. Men kan vele vragen stellen naar de zin van zo een patronaal initiatief : een daad van medelijden, die getuigt van een diep geloof, een daad van edelmoedigheit — de directie van Saint Frères had de Kerk aan de gemeente Beauval geschonken — een uiting van het patronaat dat waakt op zijn arbeiders en die werk, brood en "de hemel" verschaft of nog een leerzame les wil tonen, dat industriële vooruitgang en christelijke waarden op het einde van de XlXde eeuw kunnen verenigd worden ?
La justice comtale et le négoce de la garance dans la région de Valenciennes (deuxième moitié du XIVe siècle).
Authors: Pavot Catherine 
Published: May 2016

Justice and the Madder-dye Trade in the Valenciennes region in the Second Half of the XVIth Century.
The judiciary sources of the provostry of the Valenciennes Earldom mitigate the picture of the customary sanctions imposed on the circulation, the control and the handling of madder-dye on its territory. In opposition to the intransigence displayed by the Hainault custom and best exemplified by the municipal court and the Valenciennes "Halle aux Draps", the Earl's justice shows more flexibility in the enforcement of the sentences passed. It accepts to negotiate with the profession the possibility of getting part of the seized goods, otherwise to be destroyed, bought back. These sales benefit the Earl's finances without putting the local market at risk, as the smuggled merchandise purchased back by the trade is diposed of outside the borders of the Hainault province.
Les étudiants lillois aux XVe-XVIe siècles.
Authors: Duval Pascale 
Published: May 2016

De Rijselse studenten in de XVde-XVIde eeuw.
Dit artikel wil een beeld geven van de verplaatsingen van de Rijselse studenten tijdens hun hogere studie, in de XVde en XVIde eeuw. Er waren toen in Rijsel relatief veel lagere en latijnse scholen, maar er was geen studium voor wie wou verder studeren. Die leerlingen moesten op reis gaan. Bij het nakijken van verschillende inschrijvingsregisters van universiteiten — geen gemakkelijke taak — kon men een lijst van 800 studenten in die twee eeuwen samenstellen. Die bezochten sommige universiteiten zeer regelmatig. De studie daarvan toont het gedrag van de Rijselse studenten tijdens hun universitaire verplaatsingen.
La formation du réseau communal en France du Nord de 1790 au milieu du XIXe siècle.
Authors: Follain Antoine 
Published: May 2016

De vorming van het gemeentelijk net in Noord-Frankrijk van 1790 tot het midden van de XXste eeuw.
In 1790 erft Frankrijk een net van gemeenten dat voortkwam uit de dorpsgemeenschappen van het Ancien Régime. Het was zeer ongelijk en omvatte 41 000 districten, waarvan meer dan 8 000 in de hier bestudeerde departementen. Men verklaart deze extreme verdeling in 1790 uit de kracht van de dorpsidentiteit en, later, uit de taale weerstand tegen de fusiepolitiek van gemeenten en parochies die in de loop van de XIXde eeuw hoogten en laagten zal kennen. De bevolking veroordeelt aile redenen om kleine gemeenten af te schaffen. Het belang van de godsdienst in het idenditeitsgevoel brengt mee dat een hertekening van het parochienet tijdens het Concordaat ervaren werd als een fusie « voor de godsdienst », die het berusten in het « burgerlijke » verdwijnen aankondigde. Voor de autoriteiten was het bilan steeds ontmoedigend. En zo bleef het probleem van de kleine gemeenten bestaan tot in de XXste eeuw, terwijl in buurlanden, als België, wel recentelijk belangrijke hervormingen van de « eenheden van lokale democratie » doorgevoerd werden.
La Société Saint-Bertin de Saint-Omer, une société de prêtres voués à l'éducation au XIXe siècle. Grandeur et déclin.
Authors: Poteau Eric 
Published: May 2016

De Sint-Bertijnsocieteit in Sint-Omaars, een vereniging van priesters-leerkrachten in de XIXde eeuw. Bloeitijd en verval.
De Sint-Bertijnsocieteit, een burgerlijke vereniging van priesters- leerkrachten opgericht in 1834 in het bisdom Atrecht, had heel wat invloed op het religieuze leven van de streek en meer bepaald de kristelijke opvoeding van de jeugd. De geschiedenis van de vereniging is verbonden met de ontwikkeling van het secundair onderwijs en de uitbreiding van de vrije colleges in Noord- Frankrijk in de xixde eeuw. Na een veelbelovend begin en met de steun van de Fallouxwetten bezitten of besturen de Bertijnse priesters een twaalftal scholen in Sint-Omaars, Dohem, Marcq-en-Barœul, Sint-Winoksbergen, Rijsel, Atrecht... Daarop volgt een moeilijke période wegens de uitbreiding buiten het bisdom en de poging de societeit in een congregatie te veranderen om zo aan de bisschoppelijke voogdij te ontsnappen. Van de Ferry wetten had men geen last te meer omdat het congregatieproject niet doorging. De invloed van de societeit sproot voort uit de combinatie van een elite van priesters, voor het onderwijs, met talrijke politieke sympathisanten. De Sint-Bertijnsocieteit bleef trouw aan het monarchistische gedachtengoed en stond vijandig tegenover het Ralliement aan de Derde Republiek. Zij verdween toen het katholieke onderwijs gestructureerd werd.
Le conseil général du Pas-de-Calais et la formation des instituteurs, 1833-1871.
Authors: Renoncourt Régis 
Published: May 2016

De algemene raad van Pas-de-Calais en de vorming van de onderwijzers, 1833-1871.
In 1873, bij het begin van de Derde Republiek, bezit het département Pas-de-Calais, een van de eerste in Frankrijk qua bevolking en economische acti viteit, geen Normaalschool voor jongens noch meisjes. In het artikel analyseert men de reden van deze eigenaardige toestand en de houding van de algemene raad terzake, enerzijds zijn doorgedreven zin voor économie waar het geld van het département betreft, anderzijds een ingeboren conservatisme en diep wan- trouwen voor de laiciserende normaalschool te Douai, die een tijdje de aspirant leraars ontvangt, gepaard aan de sympatie voor de school van Dohem geleid door séculière priesters, die geen echte normaalschool kan worden en trouwens meer en meer kritiek krijgt van de academische overheid.
Dynamique technologique et politique régionale d’innovation : l’apport de l’analyse statistique des réseaux
Authors: Elouaer-Mrizak Sana , Picard Fabienne 
Published: May 2016

La Commission européenne a engagé une politique d’évolution structurelle des régions par le biais de la politique innovation. La spécialisation intelligente est apparue comme un concept phare soulevant des questions théoriques et méthodologiques importantes. Dans cet article, nous proposons d’utiliser la méthodologie d’analyse statistique des réseaux pour caractériser les tendances d’évolution techno-industrielle d’une région et en étudier les conséquences en termes de politique publique d’innovation. L’analyse statistique des réseaux caractérise les interactions entre les entités (nœuds, liens) et permet de suivre la mise en place de ces connexions et la diffusion des technologies. Les données utilisées sont celles des projets d’innovation technologiques déposés dans la région franc-comtoise et ayant reçu un financement public sur la période 2007-2012. Les résultats obtenus contribuent à interroger les modes d’élaboration des politiques publiques d’innovation. Codes JEL : O38, O25
RIPK1 and PGAM5 Control Leishmania Replication through Distinct Mechanisms
Authors: Farias Luz Nivea , Balaji Sakthi , Okuda Kendi , Barreto Aline Silva , Bertin John , Gough Peter J. , Gazzinelli Ricardo , Almeida Roque P. , Bozza Marcelo T. , Borges Valeria M. , Chan Francis Ka-Ming 
Published: May 2016

Abstract
Leishmaniasis is an important parasitic disease found in the tropics and subtropics. Cutaneous and visceral leishmaniasis affect an estimated 1.5 million people worldwide. Despite its human health relevance, relatively little is known about the cell death pathways that control Leishmania replication in the host. Necroptosis is a recently identified form of cell death with potent antiviral effects. Receptor interacting protein kinase 1 (RIPK1) is a critical kinase that mediates necroptosis downstream of death receptors and TLRs. Heme, a product of hemoglobin catabolism during certain intracellular pathogen infections, is also a potent inducer of macrophage necroptosis. We found that human visceral leishmaniasis patients exhibit elevated serum levels of heme. Therefore, we examined the impact of heme and necroptosis on Leishmania replication. Indeed, heme potently inhibited Leishmania replication in bone marrow–derived macrophages. Moreover, we found that inhibition of RIPK1 kinase activity also enhanced parasite replication in the absence of heme. We further found that the mitochondrial phosphatase phosphoglycerate mutase family member 5 (PGAM5), a putative downstream effector of RIPK1, was also required for inhibition of Leishmania replication. In mouse infection, both PGAM5 and RIPK1 kinase activity are required for IL-1β expression in response to Leishmania. However, PGAM5, but not RIPK1 kinase activity, was directly responsible for Leishmania-induced IL-1β secretion and NO production in bone marrow–derived macrophages. Collectively, these results revealed that RIPK1 and PGAM5 function independently to exert optimal control of Leishmania replication in the host.
Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
Authors: Pilely Katrine , Rosbjerg Anne , Genster Ninette , Gal Peter , Pál Gábor , Halvorsen Bente , Holm Sverre , Aukrust Pål , Bakke Siril Skaret , Sporsheim Bjørnar , Nervik Ingunn , Niyonzima Nathalie , Bartels Emil D. , Stahl Gregory L. , Mollnes Tom Eirik , Espevik Terje , Garred Peter 
Published: May 2016

Abstract
Cholesterol crystals (CC) play an essential role in the formation of atherosclerotic plaques. CC activate the classical and the alternative complement pathways, but the role of the lectin pathway is unknown. We hypothesized that the pattern recognition molecules (PRMs) from the lectin pathway bind CC and function as an upstream innate inflammatory signal in the pathophysiology of atherosclerosis. We investigated the binding of the PRMs mannose-binding lectin (MBL), ficolin-1, ficolin-2, and ficolin-3, the associated serine proteases, and complement activation products to CC in vitro using recombinant proteins, specific inhibitors, as well as deficient and normal sera. Additionally, we examined the deposition of ficolin-2 and MBL in human carotid plaques by immunohistochemistry and fluorescence microscopy. The results showed that the lectin pathway was activated on CC by binding of ficolin-2 and MBL in vitro, resulting in activation and deposition of complement activation products. MBL bound to CC in a calcium-dependent manner whereas ficolin-2 binding was calcium-independent. No binding was observed for ficolin-1 or ficolin-3. MBL and ficolin-2 were present in human carotid plaques, and binding of MBL to CC was confirmed in vivo by immunohistochemistry, showing localization of MBL around CC clefts. Moreover, we demonstrated that IgM, but not IgG, bound to CC in vitro and that C1q binding was facilitated by IgM. In conclusion, our study demonstrates that PRMs from the lectin pathway recognize CC and provides evidence for an important role for this pathway in the inflammatory response induced by CC in the pathophysiology of atherosclerosis.
Multiple IgH Isotypes Including IgD, Subclasses of IgM, and IgY Are Expressed in the Common Ancestors of Modern Birds
Authors: Han Binyue , Yuan Hui , Wang Tao , Li Bo , Ma Li , Yu Shuyang , Huang Tian , Li Yan , Fang Dongming , Chen Xiaoli , Wang Yongsi , Qiu Si , Guo Ying , Fei Jing , Ren Liming , Pan-Hammarström Qiang , Hammarström Lennart , Wang Jun , Wang Jian , Hou Yong , Pan Qingjie , Xu Xun , Zhao Yaofeng 
Published: May 2016

Abstract
Although evolutionarily just as ancient as IgM, it has been thought for many years that IgD is not present in birds. Based on the recently sequenced genomes of 48 bird species as well as high-throughput transcriptome sequencing of immune-related tissues, we demonstrate in this work that the ostrich (Struthio camelus) possesses a functional δ gene that encodes a membrane-bound IgD H chain with seven CH domains. Furthermore, δ sequences were clearly identified in many other bird species, demonstrating that the δ gene is widely distributed among birds and is only absent in certain bird species. We also show that the ostrich possesses two μ genes (μ1, μ2) and two υ genes (υ1, υ2), in addition to the δ and α genes. Phylogenetic analyses suggest that subclass diversification of both the μ and υ genes occurred during the early stages of bird evolution, after their divergence from nonavian reptiles. Although the positions of the two υ genes are unknown, physical mapping showed that the remaining genes are organized in the order μ1-δ-α-μ2, with the α gene being inverted relative to the others. Together with previous studies, our data suggest that birds and nonavian reptile species most likely shared a common ancestral IgH gene locus containing a δ gene and an inverted α gene. The δ gene was then evolutionarily lost in selected birds, whereas the α gene lost in selected nonavian reptiles. The data obtained in this study provide significant insights into the understanding of IgH gene evolution in tetrapods.
Near-field Imaging Point-like Scatterers and Extended Elastic Solid in a Fluid
Authors: Yin Tao , Hu Guanghui , Xu Liwei 
Published: May 2016

AbstractConsider the time-harmonic acoustic scattering from an extended elastic body surrounded by a finite number of point-like obstacles in a fluid. We assume point source waves are emitted from arrayed transducers and the signals of scattered near-field data are recorded by receivers not far away from the scatterers (compared to the incident wavelength). The forward scattering can be modeled as an interaction problem between acoustic and elastic waves together with a multiple scattering problem between the extend solid and point scatterers. We prove a necessary and sufficient condition that can be used simultaneously to recover the shape of the extended elastic solid and to locate the positions of point scatterers. The essential ingredient in our analysis is the outgoing-to-incoming (OtI) operator applied to the resulting near-field response matrix (or operator). In the first part, we justify the MUSIC algorithm for locating point scatterers from near-field measurements. In the second part, we apply the factorization method, the continuous analogue of MUSIC, to the two-scale scattering problem for determining both extended and point scatterers. Numerical examples in 2D are demonstrated to show the validity and accuracy of our inversion algorithms.
A Dimensional Splitting of ETD Schemes for Reaction-Diffusion Systems
Authors: Asante-Asamani E. O. , Wade Bruce A. 
Published: May 2016

AbstractNovel dimensional splitting techniques are developed for ETD Schemes which are second-order convergent and highly efficient. By using the ETD-Crank-Nicolson scheme we show that the proposed techniques can reduce the computational time for nonlinear reaction-diffusion systems by up to 70%. Numerical tests are performed to empirically validate the superior performance of the splitting methods.