bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Fora da Beleza não há salvação”: O movimento de Rubem Alves da fé engajada à teopoesia.
Authors: Terra Kenner Roger Cazotto , De Luiz Rainerson Israel Estevam 
Published: September 2017

Na década de sessenta, na América Latina, surgia uma perspectiva teológica a partir do contexto dos pobres, da sociedade industrial e da própria teologia clássica à luz da fé engajada. Rubem Alves é considerado um dos precursores ou, no mínimo, parte das origens dessa teologia latino-americana conhecida como Teologia da Libertação. Contudo, na sua caminhada intelectual, percebemos o movimento da ênfase do fazer para a prioridade da beleza. Neste artigo, apresentar-se-á o processo alvesiano de distanciamento de uma linguagem teológico-emancipatória para se descobrir livre na beleza dos versos e das crônicas infantis. Alves propõe uma libertação corporal de todas as estruturas tecnológicas e teológicas de repressão, para que o corpo viva o sentido lúdico, imaginativo, poético e dionisíaco da vida. Nesse artigo, para percebermos esse movimento alvesiano, investigaremos as propostas de seu humanismo messiânico e visualizaremos, desde o final da década de 60, os primeiros lampejos de sua teopoesia. Portanto, mostrar-se-á o vanguardismo de Rubem Alves e suas relações frutíferas com as teorias da linguagem e como a poesia, a qual lhe serviu como instrumento de construção de mundo e crítica estética à mecanicidade do saber tecnológico e à teologia tradicional.
KANDUNGAN 226Ra, 210Pb, 210Po DAN 40K PADA BEBERAPA TEMBAKAU ROKOK DI INDONESIA
Authors: Sukmabuana Putu 
Published: September 2017

Kandungan 226Ra, 210Pb, 210Po dan 40K pada beberapa tembakau rokok di Indonesia. Pada penelitian ini telah dilakukan pengukuran radionuklida alam 226Ra, 210Pb, 210Po dan 40K yang terkandung didalam tembakau rokok, tujuannya untuk memperkirakan dosis efektif yang diterima oleh orang yang menghisap asap rokok. Sampel tembakau yang telah diukur meliputi 14 merek rokok yang umum dijual dan dikonsumsi di Indonesia. Konsentrasi 226Ra, 210Pb dan 40K diukur menggunakan spektrometri sinar γ, didapat konsentrasi 226Ra bervariasi dari 2,86 hingga 6,04 Bq/kg, rata-rata 4,18 ± 0.67 Bq/kg, untuk 210Pb bervariasi dari 3,04 hingga 6,76 Bq/kg rata-rata 4,71 ± 0.82 Bq/kg, sedangkan konsentrasi 40K bervariasi dari 23,57 hingga 32,69 Bq/kg rata-rata 26,50 ± 2,08 Bq/kg. 210Po dihitung berdasarkan kesetimbangan radioaktif, hasilnya bervariasi dari 2,65 hingga 5,88 Bq/kg rata-rata 4,09 ± 0,71 Bq/kg. Dengan menggunakan koefisen dosis efektif yang diberikan oleh ICRP, dapat dilakukan estimasi dosis efektif tahunan yang diterima oleh perokok. Rata-rata dosis efektif tahunan untuk 226Ra adalah 80,46 ± 12,93 µSv/tahun, untuk 210Pb rata-rata 28,47 ± 4,96 µSv/tahun, dan 210Po rata-rata 74,31 ± 12,96 µSv/tahun. Dengan menjumlahkan dosis rata-rata dari 226Ra, 210Pb dan 210Po, didapat total estimasi dosis efektif rata-rata pertahun 183,24 µSv/tahun atau sekitar 14,5% dari batas dosis paparan radiasi secara inhalasi di dunia 1260 µSv/tahun. Estimasi dosis efektif radionuklida 40K tidak dapat dilakukan karena koefisien dosis untuk 40K tidak tersedia di ICRP 71.
Prevalence of co-existence genes and clonal spread of ESBL-producing isolates causing hospital and community-acquired infections in Zenica-Doboj Canton, Bosnia and Herzegovina
Authors: Ibrahimagić Amir , Uzunović Selma , Bedenić Branka 
Published: September 2017

Introduction: Co-existence type of ESBL-producing isolates are serious problem in the public health world.
Methods Antibiotic susceptibility was determined by disc diffusion and broth microdilution according to CLSI guidelines. Double-disk synergy test was performed in order to screen for ESBLs/pAmpC beta-lactamases. PCR was used to detect blaESBL/blaampC/blacarb genes. Genetic relatedness of the strains was determined by pulsed-field-gel-electrophoresis (PFGE).
Results In this study 88 of the inpatient isolates (n=126; 10.0%) and 62 of the outpatient (n=184; 6.4%) Beta-lactamase-producing isolates were taken for the study. They included 50.0/29.0% K. pneumoniae, 12.5/30.6% E. coli, 11.4/4.8% A. baumannii, 8.0/14.5% K. oxytoca, 8.0/4.8% E. cloacae, 5.7/8.1% Proteus spp., and less than 3.5% of other isolates. Co-existence of more than two type of beta-lactamases was detected in 77.3% of inpatient and 45.2% of outpatient isolates. Among inpatient isolates, Klebsiella spp. and E. coli were the most frequent isolates which produce more than two type of genes; in ≈ 65% and ≈12% cases. Separately, combination of four: TEM+SHV+CTX-M+OXA-1 beta-lactamases in inpatient K. pneumoniae isolates were detected in 63.6% cases respectively. Differents in antimicrobial resistance were higher to cephalosporins agents in Klebsiella spp., and E. coli at inpatient and outpatient isolates which produce more than two types of beta-lactamases than in isolates which produce one type of beta-lactamases.
Conclusion: This work demonstrates a progressively increasing prevalence of co-existence type of beta-lactamases expecially in inpatient isolates. Continous monitoring and surveillance and proper infection control and prevention practice will limit the further spread of these isolates.
Adherence to antiretroviral therapy and factors affecting adherence among paediatric HIV patients
Authors: Govind Kendre , Yashwant Gabhale , Nikita Shah , Vishal Jadhav , Kunal Nath , Mamta Manglani 
Published: September 2017

Background: Adherence to antiretroviral therapy (ART) is the strongest indicator of successful treatment of Human Immunodeficiency Virus (HIV) among children. The main aim of the present study was to know the prevalence of adherence at our centre and various factors affecting the adherence in children.Methods: It was an observational study done in children less than 15 years of age, affected with HIV. 78 children attending Paediatric Centre of Excellence (PCOE) for HIV L.T.M.G. Hospital, Sion, Mumbai were included in study, Study period was 18 months from January 2012 to June 2013. Complete history of the patients was noted in a pre-designed proforma. Baseline investigations related to HIV were done in all children. Fixed dose combination ART was started in children who fulfilled clinical and/or immunological criteria as per the NACO guidelines. Adherence was estimated using Pill count method..All the data were analysed by using 10.0 version of statistical software SPSS.Results: In this study, male children (57.7%) out numbered the females (42.3%). Majority of study subjects were more than 10 years of age. Overall adherence among subjects was 82.1% at the end of one year and non-adherence was 17.9%. There was no significant association of age and gender of the patients with adherence (p>0.05). Education, employment and knowledge towards medication of care takers was significantly associated with adherence of ART (p<0.05). Adherence of study cases had not showed any significant association with ART treatment regimen (p=0.99). At the end of one year, the mean CD4 count was significantly more as compared to baseline among adherence group and the mean CD4 count was significantly less as compared to baseline among non-adherence group. The most common reason for missed dosage was forgot to take medicine in 29 subjects (37.1 %)..Conclusion: Adherence level in this study was good. Forgot to take the medicine was the main reason given by the patients for non-adherence. Education, employment and knowledge towards medication of care takers was significantly associated with adherence of ART .But further studies are needed to explore various other factors related to adherence in children.
Biosimilars: State of Clinical and Regulatory Science
Authors: Klein Agnes Victoria , Wang Jian , Feagan Brian G. , Omoto Mark 
Published: September 2017

On May 12, 2017, various issues and challenges associated with biologics were discussed during a session of the annual joint conference of Canadian Society for Pharmaceutical Sciences and Canadian Chapter of Controlled Release Society at Hyatt Regency Hotel, Montréal, QC, Canada. An update on the Canadian regulatory guidelines for biosimilars was given, followed by viewpoints expressed by regulatory, academic and industry scientists. Topics of discussion included: reference biologic drug, clinical considerations, immunogenicity, extrapolation and clarification of terminology, product monograph, international collaboration, switching and interchangeability, naming conventions, clinical and non-clinical evaluation, authorization of indications, statistical equivalence, the nor-switch study and biologics marketplace.
Combination of bone graft and resorbable membrane for alveolar ridge preservation: A systematic review, meta‐analysis, and trial sequential analysis
Authors: Troiano Giuseppe , Zhurakivska Khrystyna , Lo Muzio Lorenzo , Laino Luigi , Cicciù Marco , Lo Russo Lucio 
Published: September 2017

AbstractIntroductionAlveolar ridge preservation (ARP) techniques aim to reduce resorption after tooth extraction. The combination of a graft material covered with a resorbable membrane represents one of the most common strategies performed in the clinical practice. The aim of this systematic review is to analyze evidence regarding potential benefits of ARP procedures performed with allogenic/xenogenic grafts in combination with a resorbable membrane coverage in comparison with spontaneous healing.MethodsElectronic databases were screened independently to select studies suitable for inclusion in this review. Horizontal ridge width reduction (HRWR) and vertical ridge height reduction (VRHR) were investigated as primary outcomes and volume changes (VC) as a secondary outcome. Meta‐analysis was performed using the inverse of variance test with a random effect model. Adjustment for Type I and II errors and analysis of the power of evidence was performed with trial sequential analysis (TSA).ResultsSeven studies met the inclusion criteria and were included in the quantitative synthesis. Meta‐analysis revealed that the combination therapy resulted in a lower rate of resorption for both HRWR (−2.19 mm, 95% confidence interval [CI]: −2.67 to −1.71 mm) and VRHR (−1.72 mm, 95% CI: −2.14 to −1.30 mm). For VC no meta‐analysis was performed due to insufficient data. Analysis of the power of the evidence performed with TSA showed that the number of both studies and sockets analyzed is sufficient to validate such findings, despite the high rate of heterogeneity.ConclusionsUse of bone graft covered by a resorbable membrane can decrease the rate of alveolar ridge horizontal and vertical resorption after tooth extraction. The power and reliability of the evidence is strong enough to confirm the above‐mentioned findings, despite the high rate of heterogeneity of included studies.
Estado de la 25-hidroxivitamina D sérica en niños sanos menores de 10 años del área metropolitana de Barranquilla
Authors: Acosta-Bendek Belle Marie , Sánchez-Majana Lucia Patricia , Fonseca-Galé Jennifer , Posada-Valencia Rocío , Rodríguez-Leyton Mylene , Sarmiento-Rubiano Luz Adriana 
Published: September 2017

Objetivo. Evaluar los niveles séricos de 25-hidroxivitamina D (25-OH-D) en niños sanos menores de 10 años del área metropolitana de Barranquilla (AMB). Material y métodos. Estudio descriptivo de corte transversal, que evaluó los niveles séricos de 25-OH-D en 360 niños del AMB en los años 2014-2015. Resultados. El valor promedio de 25-OH-D en la población estudiada fue 32.23±8.56 ng/mL; 46.38% de los niños tenía niveles de vitamina D considerados insuficientes (<30 ng/mL) y 3.05% mostro deficiencia (<20 ng/mL). Soledad y Puerto Colombia fueron los municipios con mayor población en esta condición. Conclusiones. Es necesario generar programas de suplementación nutricional y fomentar estilos de vida que permitan, de forma segura, mejorar los niveles de vitamina D en la población.
Novel insights into the coagulation process for pharmaceutical wastewater treatment with fluorescence EEMs-PARAFAC
Authors: Gou Xiying , Zhang Panyue , Song Yonghui , Qian Feng , Yu Huibing , Zeng Guangming 
Published: September 2017

Abstract
In this study, coagulation process was applied to treat the effluent of pharmaceutical wastewater using polymeric ferric sulfate as a coagulant. Three-dimensional excitation-emission matrix fluorescence spectroscopy coupled with parallel factor analysis (EEMs-PARAFAC) was applied to investigate the fluorescent characteristics of dissolved organic matter (DOM) from pharmaceutical wastewater and the reduction of contaminant and fluorescent variations in the coagulation process. It shows that coagulation was effective to remove contaminants in the effluent of pharmaceutical wastewater, and the optimum coagulate dosage was 0.5 g/L, where the removal efficiency of total organic matter (TOC), UV254, turbidity and NH4+-N were achieved 44.2%, 43.3%, 87.0% and 10.27%, respectively. Five fluorescence components were identified by EEMs-PARAFAC, including one fulvic-like component (C1), one xenobiotic-like component (C2), two humic-like components (C3 and C5) and one protein-like component (C4); DOM of pharmaceutical wastewater was dominated by C3, C4 and C2. Under the optimum coagulation condition, the decreasing order of removal efficiencies was C5 (49.92%), C3 (40.95%), C4 (10.58%), C2 (9.68%) and C1 (5.05%). Principal component analysis (PCA) showed C3, C5 had remarkable correlations with TOC and UV254, suggesting that C3 and C5 may be a good indicator for the reduction of TOC and UV254. PCA indicated that the EEM-PARAFAC could be successfully applied to the evaluation of the coagulation efficiency for pharmaceutical wastewater treatment.
Comparison of Composition and Anticaries Effect of Galla Chinensis Extracts with Different Isolation Methods
Authors: Huang Xuelian , Deng Meng , Liu Mingdong , Cheng Lei , Exterkate R.A.M. , Li Jiyao , Zhou Xuedong , Ten Cate Jacob. M. 
Published: September 2017

Objectives:Galla chinensiswater extract (GCE) has been demonstrated to inhibit dental caries by favorably shifting the demineralization/remineralization balance of enamel and inhibiting the biomass and acid formation of dental biofilm. The present study focused on the comparison of composition and anticaries effect ofGalla chinensisextracts with different isolation methods, aiming to improve the efficacy of caries prevention.Methods:The composition of water extract (GCE), ethanol extract (eGCE) and commercial tannic acid was compared. High performance liquid chromatography coupled to electrospray ionization-time of flight-mass spectrometry (HPLC-ESI-TOF-MS) analysis was used to analyze the main ingredients.In vitropH-cycling regime and polymicrobial biofilms model were used to assess the ability of differentGalla chinensisextracts to inhibit enamel demineralization, acid formation and biofilm formation.Results:All the GCE, eGCE and tannic acid contained a high level of total phenolics. HPLC-ESI-TOF-MS analysis showed that the main ingredients of GCE were gallic acid (GA), while eGCE mainly contained 4-7 galloylglucopyranoses (GGs) and tannic acid mainly contained 5-10 GGs. Furthermore, eGCE and tannic acid showed a better effect on inhibiting enamel demineralization, acid formation and biofilm formation compared to GCE.Conclusions:Galla chinensisextracts with higher tannin content were suggested to have higher potential to prevent dental caries.
Multidirectional Instability: Natural History and Evaluation
Authors: Navlet Miguel García , Asenjo-Gismero Cristina Victoria 
Published: September 2017

Background:
Multidirectional instability (MDI) represents a great challenge to the orthopedic surgeon. When treating these patients we must be aware that instability refers to a symptomatic situation, thus multidirectional instability is defined as symptomatic involuntary instability in two or more directions, and should be clearly differentiated from asymptomatic hyperlaxity.
It may be associated with hyperlaxity, either congenital or acquired following repetitive stress, but also may be present without hyperlaxity, which is rare.

Methods:
We searched in the online data bases and reviewed the relevant published literature available.

Results:
Many differences can be seen in the current literature when identifying these patients, unclear definitions and criteria to be included in this patient group are common.

Conclusion:
Understanding the complex shoulder biomechanics as well as being aware of the typical clinical features and the key examination signs, which we review in this article, is of paramount importance in order to identify and classify these patients, allowing the best treatment option to be offered to each patient.
Controversies in the Surgical Management of Shoulder Instability: Open vs Arthroscopic Procedures
Authors: Huerta Alejandro , Rincón Gustavo , Peidro Lluis , Combalia Andreu , Sastre Sergi 
Published: September 2017

Background:Traumatic anterior instability of the shoulder is a common condition associated with a high recurrence rate in young adults. Operative treatment reduces the risk of recurrence. Several studies have compared arthroscopic and open shoulder instability repair. The purpose of this paper is to perform a review of the literature where both techniques are compared in the repair of the anterior shoulder instability without bone loss.Methods:Prior to arthroscopy, recurrent dislocations were managed by open repair. There have been many studies documenting low recurrence rates after open Bankart stabilization.Initially, arthroscopic fixation reported high failure rates.Results:In the last 20 years, the development of arthroscopic stabilization for recurrent anterior instability has improved failure rates. In comparison with open techniques, arthroscopic procedures have the advantages of decreased morbidity rate, early functional rehabilitation and improved range of motion.Conclusion:The available evidence does not show a statistically significant difference in outcome measures between arthroscopic and open repair for the treatment of recurrent anterior shoulder instability. Given the similar results between the 2 groups, differences in length of hospital stay and cost to the patient and society point to arthroscopic repair as the more judicious treatment approach.
Arthroscopic Soft Tissue Procedures for Anterior Shoulder Instability
Authors: Brown Mathew , Wallace Andrew , Lachlan Andrew , Alexander Susan 
Published: September 2017

Background:Arthroscopy has rapidly transformed the treatment of anterior shoulder instability over the past 30 years. Development of arthroscopic equipment has permitted the investigation and diagnosis of the unstable shoulder, and fixation methods have evolved to promote arthroscopy from an experimental procedure to one of first-line mainstream treatment.Methods:Key research papers were reviewed to identify the fundamental principles in patient diagnosis and appropriate selection for arthroscopic treatment. The evolution of arthroscopy is described in this article to facilitate the understanding of current treatment.Results:Accurate diagnosis of the shoulder instability subtype is essential prior to selection for surgery. Different surgical techniques are described to address different pathology within the glenohumeral joint related to instability and the appropriate method should be selected accordingly to optimise outcome.Conclusion:Anterior shoulder instability can be treated successfully using arthroscopic surgery, but the surgeon must treat each patient as an individual case and recognise the different subtypes of instability, the associated pathological lesions and the limitations of arthroscopy. The article concludes with a suggested algorithm for the treatment of anterior shoulder instability.
Controversies in the Management of the First Time Shoulder Dislocation
Authors: Avila Lafuente José Luis , Moros Marco Santos , García Pequerul José Manuel 
Published: September 2017

Background:Traditionally, initial management of first anterior shoulder dislocations consists of reduction of the glenohumeral joint followed by a period of immobilization and subsequent physical therapy to recover shoulder range of motion and strength. This traditional approach in management is now controversial due to the high rate of recurrence. The aim of this paper is to review and discuss the literature about the global management of patients presenting with first-time traumatic anterior glenohumeral dislocation, analyzing the factors that affect shoulder instability after the first episode of dislocation.Methods:Scientific publications about the management of first-time shoulder dislocations are reviewed. Pubmed is used for that and no limit in the year of publication are stablished. These papers and their conclusions are discussed.Results:Younger patients, patient´s activities and the kind of injury are the most important factors related to the shoulder instability after a first time traumatic dislocation. Authors that recommend surgical treatment after the first episode of dislocation argue that the possibilities of recurrence are high and therefore surgery should be performed before its occurrence. Other authors, however, argue that surgical treatment is demanding, and keep in mind that complications, such as recurrence, stiffness and pain after surgery, are still present.Conclusion:Currently, there is still no consensus in the literature with regard to the management of first episode of shoulder dislocation. It is necessary to analyze carefully every individual case to manage them more or less aggressive to obtain the best result in our practice.
Medial Patellofemoral Ligament Reconstruction Using the Hamstring Tendon for Patellofemoral Joint Instability in an 81-Year-Old Female
Authors: Takahashi Tsuneari , Takeshita Katsushi 
Published: September 2017

Introduction:
Chronic patellofemoral instability occurs mainly in adolescent females and can also be induced by medial patellofemoral ligament (MPFL) injury. There are no case reports of MPFL reconstruction for chronic patellofemoral instability due to MPFL injury in aged populations.

Case Presentation:
81-year-old female presented with left knee pain, giving way, and patellar instability while climbing stairs, which continued for 18 months. Patellar apprehension test was positive, and roentgenogram showed lateral patellar subluxation. Conservative therapy was not successful; hence, we performed a lateral release and MPFL reconstruction surgery.

Operative Procedure:
After arthroscopic lateral release, the hamstring tendon was harvested, and a graft composite made of doubled hamstring tendon and polyester tape with a suspensory fixation device was prepared. Then, a femoral bone tunnel was constructed in a socket shape at the anatomical footprint of the MPFL. The graft was passed through the femoral tunnel, and free ends of the graft composite were sutured to the periosteum of the patella, using two suture anchors at 60° of knee flexion with patellar reduction. Physiotherapy was gradually started using a patella-stabilizing orthosis on the first postoperative day. Her Kujala score improved from 66 to 97 points, and Barthel index score improved from 70 to 100 points at 1 year after surgery. She neither developed patellofemoral joint OA nor had any recurrence of symptoms at the 5-year postoperative follow up.

Conclusion
MPFL reconstruction using the hamstring tendon is an effective procedure for patients with chronic patellofemoral instability even after the age of 80 years.