bluuebunny/crossref_metadata_2025_split huggingface dataset:
A meta‐analysis of the relation between therapeutic alliance and treatment outcome in eating disorders
Authors: Graves Tiffany A. , Tabri Nassim , Thompson‐Brenner Heather , Franko Debra L. , Eddy Kamryn T. , Bourion‐Bedes Stephanie , Brown Amy , Constantino Michael J. , Flückiger Christoph , Forsberg Sarah , Isserlin Leanna , Couturier Jennifer , Paulson Karlsson Gunilla , Mander Johannes , Teufel Martin , Mitchell James E. , Crosby Ross D. , Prestano Claudia , Satir Dana A. , Simpson Susan , Sly Richard , Lacey J. Hubert , Stiles‐Shields Colleen , Tasca Giorgio A. , Waller Glenn , Zaitsoff Shannon L. , Rienecke Renee , Le Grange Daniel , Thomas Jennifer J. 
Published: February 2017

AbstractThe therapeutic alliance has demonstrated an association with favorable psychotherapeutic outcomes in the treatment of eating disorders (EDs). However, questions remain about the inter‐relationships between early alliance, early symptom improvement, and treatment outcome. We conducted a meta‐analysis on the relations among these constructs, and possible moderators of these relations, in psychosocial treatments for EDs. Twenty studies met inclusion criteria and supplied sufficient supplementary data. Results revealed small‐to‐moderate effect sizes, βs = 0.13 to 0.22 (p < .05), indicating that early symptom improvement was related to subsequent alliance quality and that alliance ratings also were related to subsequent symptom reduction. The relationship between early alliance and treatment outcome was partially accounted for by early symptom improvement. With regard to moderators, early alliance showed weaker associations with outcome in therapies with a strong behavioral component relative to nonbehavioral therapies. However, alliance showed stronger relations to outcome for younger (vs. older) patients, over and above the variance shared with early symptom improvement. In sum, early symptom reduction enhances therapeutic alliance and treatment outcome in EDs, but early alliance may require specific attention for younger patients and for those receiving nonbehaviorally oriented treatments.
Caribbean massive corals not recovering from repeated thermal stress events during 2005–2013
Authors: Neal Benjamin Paul , Khen Adi , Treibitz Tali , Beijbom Oscar , O'Connor Grace , Coffroth Mary Alice , Knowlton Nancy , Kriegman David , Mitchell B. Greg , Kline David I. 
Published: February 2017

AbstractMassive coral bleaching events associated with high sea surface temperatures are forecast to become more frequent and severe in the future due to climate change. Monitoring colony recovery from bleaching disturbances over multiyear time frames is important for improving predictions of future coral community changes. However, there are currently few multiyear studies describing long‐term outcomes for coral colonies following acute bleaching events. We recorded colony pigmentation and size for bleached and unbleached groups of co‐located conspecifics of three major reef‐building scleractinian corals (Orbicella franksi, Siderastrea siderea, and Stephanocoenia michelini; n = 198 total) in Bocas del Toro, Panama, during the major 2005 bleaching event and then monitored pigmentation status and changes live tissue colony size for 8 years (2005–2013). Corals that were bleached in 2005 demonstrated markedly different response trajectories compared to unbleached colony groups, with extensive live tissue loss for bleached corals of all species following bleaching, with mean live tissue losses per colony 9 months postbleaching of 26.2% (±5.4 SE) for O. franksi, 35.7% (±4.7 SE) for S. michelini, and 11.2% (±3.9 SE) for S. siderea. Two species, O. franksi and S. michelini, later recovered to net positive growth, which continued until a second thermal stress event in 2010. Following this event, all species again lost tissue, with previously unbleached colony species groups experiencing greater declines than conspecific sample groups, which were previously bleached, indicating a possible positive acclimative response. However, despite this beneficial effect for previously bleached corals, all groups experienced substantial net tissue loss between 2005 and 2013, indicating that many important Caribbean reef‐building corals will likely suffer continued tissue loss and may be unable to maintain current benthic coverage when faced with future thermal stress forecast for the region, even with potential benefits from bleaching‐related acclimation.
Dissociated patterns of anti‐correlations with dorsal and ventral default‐mode networks at rest
Authors: Chen Jingyuan E. , Glover Gary H. , Greicius Michael D. , Chang Catie 
Published: February 2017

Abstract:Previous studies of resting state functional connectivity have demonstrated that the default‐mode network (DMN) is negatively correlated with a set of brain regions commonly activated during goal‐directed tasks. However, the location and extent of anti‐correlations are inconsistent across different studies, which has been posited to result largely from differences in whether or not global signal regression (GSR) was applied as a pre‐processing step. Notably, coordinates of seed regions‐of‐interest defined within the posterior cingulate cortex (PCC)/precuneus, an area often employed to study functional connectivity of the DMN, have been inconsistent across studies. Taken together with recent observations that the DMN contains functionally heterogeneous subdivisions, it is presently unclear whether these seeds map to different DMN subnetworks, whose patterns of anti‐correlation may differ. If so, then seed location may be a non‐negligible factor that, in addition to differences in preprocessing steps, contributes to the inconsistencies reported among published studies regarding DMN correlations/anti‐correlations. In this study, they examined anti‐correlations of different subnetworks within the DMN during rest using both seed‐based and point process analyses, and discovered that: (1) the ventral branch of the DMN (vDMN) yielded significantly weaker anti‐correlations than that associated with the dorsal branch of the DMN (dDMN); (2) vDMN anti‐correlations introduced by GSR were distinct from dDMN anti‐correlations; (3) PCC/precuneus seeds employed by earlier studies mapped to different DMN subnetworks, which may explain some of the inconsistency (in addition to preprocessing steps) in the reported DMN anti‐correlations. Hum Brain Mapp 38:2454–2465, 2017. © 2017 Wiley Periodicals, Inc.
Cornea and its adaptation to environment and accommodation function in veiled chameleon (Chamaeleo calyptratus): ultrastructure and 3D transmission electron tomography
Authors: Akhtar Saeed , Khan Adnan A , Albuhayzah Hussain A , Almubrad Turki M 
Published: February 2017

AbstractWe investigate the ultrastructural features and 3D electron tomography of chameleon (Chamaeleon calyptratus) which is a native of desert environments of Saudi Arabia. The corneas of the chameleon were fixed in 2.5% glutaraldehyde containing cuprolinic blue in sodium acetate buffer for electron microscopy and tomography, and observed under a JEOL 1400 transmission electron microscope. The thin cornea (21.92 μm) contained 28–30 collagen fibril lamellae. The middle stromal lamellae (from 13 to 19) contained keratocytes with a long cell process and filled with granular material. The CF diameter increased from lamella 1 (30.44 ± 1.03) to Lamella 5 (52.83 ± 2.00) then decreased towards the posterior stoma. The percentage of large CF diameters (55–65 nm) was very high in the lamellae L14 (38.8%) and L15 (85.7%). The mean PGs area of the posterior stroma (448.21 ± 24.84 nm2) was significantly larger than the mean PGs area of the anterior, (309.86 ± 8.2 nm2) and middle stroma 245.94 ± 8.28 nm2). 3D electron tomography showed the distribution of PGs around and over the CF. Variable diameters of CFs in the anterior stroma may provide compact lamellae which may restrict the low wavelength of light. Variable diameters of CFs in the anterior stroma may provide compact lamellae which may restrict the low wavelength of light. This accommodation function is achieved by bending of the cornea. During bending the anterior stroma was stretched and the posterior stroma was compressed due to the presence of small CFs. The middle stroma remained stiff due to the presence of large CFs. Large proteoglycans not only maintain hydration for a longer period of time, but also act as a lubricant to neutralise the shear forces in the anterior and posterior stroma during bending.
The Consumption of Household Goods, Bargaining Power and their Relationship with a Conditional Cash Transfer Program in Peru
Authors: García Luis 
Published: February 2017

AbstractThis research assesses the effect of the JUNTOS cash transfer program on the consumption of certain merit goods (such as food) and demerit goods (such as alcoholic drinks). We address the following question: What is the impact of the cash transfer on the consumption of these goods? This research utilises socioeconomic information from the Peruvian National Household Survey 2009–2014. The results of the fixed‐effects estimates show that the JUNTOS program's beneficiary households spend a large proportion of the family budget on food consumption, children's clothing and education, while no impact is found on consumption of soft drinks, alcoholic drinks and tobacco. Copyright © 2017 John Wiley & Sons, Ltd.
Diffusion tensor imaging of the human calf: Variation of inter‐ and intramuscle‐specific diffusion parameters
Authors: Schlaffke Lara , Rehmann Robert , Froeling Martijn , Kley Rudolf , Tegenthoff Martin , Vorgerd Matthias , Schmidt‐Wilcke Tobias 
Published: February 2017

PurposeTo investigate to what extent inter‐ and intramuscular variations of diffusion parameters of human calf muscles can be explained by age, gender, muscle location, and body mass index (BMI) in a specific age group (20–35 years).Materials and MethodsWhole calf muscles of 18 healthy volunteers were evaluated. Magnetic resonance imaging (MRI) was performed using a 3T scanner and a 16‐channel Torso XL coil. Diffusion‐weighted images were acquired to perform fiber tractography and diffusion tensor imaging (DTI) analysis for each muscle of both legs. Fiber tractography was used to separate seven lower leg muscles. Associations between DTI parameters and confounds were evaluated. All muscles were additionally separated in seven identical segments along the z‐axis to evaluate intramuscular differences in diffusion parameters.ResultsFractional anisotropy (FA) and mean diffusivity (MD) were obtained for each muscle with low standard deviations (SDs) (SDFA: 0.01–0.02; SDMD: 0.07–0.14(10−3)). We found significant differences in FA values of the tibialis anterior muscle (AT) and extensor digitorum longus (EDL) muscles between men and women for whole muscle FA (two‐sample t‐tests; AT: P = 0.0014; EDL: P = 0.0004). We showed significant intramuscular differences in diffusion parameters between adjacent segments in most calf muscles (P < 0.001). Whereas muscle insertions showed higher (SD 0.03–0.06) than muscle bellies (SD 0.01–0.03), no relationships between FA or MD with age or BMI were found.ConclusionInter‐ and intramuscular variations in diffusion parameters of the calf were shown, which are not related to age or BMI in this age group. Differences between muscle belly and insertion should be considered when interpreting datasets not including whole muscles.Level of Evidence: 3Technical Efficacy: Stage 1J. Magn. Reson. Imaging 2017;46:1137–1148.
Dual echo Dixon imaging with a constrained phase signal model and graph cuts reconstruction
Authors: Stinson Eric G. , Trzasko Joshua D. , Fletcher Joel G. , Riederer Stephen J. 
Published: February 2017

PurposeThe purpose of this work is to derive and demonstrate constrained‐phase dual‐echo Dixon imaging within a maximum likelihood framework solved with a regularized graph‐cuts‐guided optimization.Theory and MethodsDual‐echo Dixon reconstruction is fundamentally underdetermined; however, adopting a constrained‐phase signal model reduces the number of unknowns and the nonlinear problem can be solved under a maximum likelihood framework. Period shifts in the field map (manifesting as fat/water signal swaps) must also be corrected. Here, a regularized cost function promotes a smooth field map and is solved with a graph‐cuts‐guided greedy binary optimization. The reconstruction shown here is compared to two other prevalent Dixon reconstructions in experimental phantom and human studies.ResultsReconstructed images of the water and fat signal are shown for a phantom study, and in vivo studies of foot/ankle, pelvis, and CE‐MRA of the thighs. The method shown here compared favorably with the other two methods. Large field inhomogeneities on the order of 20 ppm were resolved, thereby avoiding the fat and water signal swaps present in images reconstructed with the other methods.ConclusionConstrained‐phase dual‐echo Dixon imaging solved with a regularized graph‐cuts‐guided optimization has been derived and demonstrated to successfully separate water and fat images in the presence of large magnetic field inhomogeneities. Magn Reson Med 78:2203–2215, 2017. © 2017 International Society for Magnetic Resonance in Medicine.
Glutathione‐S‐transferase P1 may predispose children to a decline in pulmonary function after stem cell transplant
Authors: Stark Julie , Renbarger Jamie , Slaven James , Yu Zhangsheng , Then Jenny , Skiles Jodi , Davis Stephanie 
Published: February 2017

AbstractRATIONALEPulmonary complications after hematopoietic stem cell transplant (SCT) are associated with increased mortality. Genetic markers for those at risk for pulmonary impairment post‐SCT have not been widely investigated.METHODSForty‐nine patients were retrospectively selected from a single institution's biorepository with linked clinical data. All subjects performed pre‐SCT PFTs. Genotyping was conducted using the Infinium Exome‐24 BeadChip. Four single nucleotide polymorphisms (SNPs) were selected (rs1800871, rs1695, rs1800629, rs12477314) and evaluated for association with PFT parameters as change over time from baseline. Associations between SNPs and PFT parameters were assessed and adjusted for the following confounding variables: age, gender, and race.RESULTSUsing the recessive genetic model, patients with one or two minor alleles for the glutathione S‐transferase P1 (GSTP1) SNP rs1695 had a lower decline in FEV1 and FEF25‐75 at 1‐year post‐SCT compared to patients who were homozygous for the ancestral allele (adjusted P‐values <0.01 and 0.02, respectively). No other SNPs were significantly associated with other PFT parameters.CONCLUSIONSOur findings suggest that GSTP1 genotype may be associated with lung function during the first year post‐SCT. Identifying and investigating genes that predispose patients to pulmonary complications after SCT may allow for more personalized patient management based on pre‐emptive genetic testing. The glutathione S‐transferase gene merits further investigation.
Influence of chorionicity and gestational age at single fetal loss on risk of preterm birth in twin pregnancy: analysis of STORK multiple pregnancy cohort
Authors: D'Antonio F. , Thilaganathan B. , Dias T. , Khalil A. ,   on behalf of the Southwest Thames Obstetric Research Collaborative (STORK)
Published: February 2017

ABSTRACTObjectiveSingle intrauterine death (sIUD) in twin pregnancy is associated with a significant risk of cotwin demise and preterm birth (PTB), especially in monochorionic (MC) twins. However, it is yet to be established whether the gestational age at loss may influence the pregnancy outcome. The aim of this study was to explore the risk of PTB according to the gestational age at diagnosis of sIUD.MethodsThis was a cohort study of all twin pregnancies booked for antenatal care in a large regional network of nine hospitals over a 10‐year period. Ultrasound data were matched to hospital delivery records and to a mandatory national register for stillbirth and neonatal loss provided by the Centre for Maternal and Child Enquires. Cases with double fetal loss at the time of the scan and cases of sIUD occurring at or after 34 weeks of gestation were not included in the analysis. The relative risk (RR) of PTB at < 34, < 32 and < 28 weeks of gestation in twin pregnancies complicated by sIUD was assessed and compared with that in twin pregnancies without fetal loss. The risk of PTB at < 34 weeks was stratified according to the gestational age at diagnosis of sIUD. The risk of PTB in twin pregnancy after sIUD according to the gestational age at death was also explored.ResultsThe analysis included 3013 twin gestations (2469 dichorionic (DC) and 544 MC). Median gestational age at birth was lower in the pregnancies complicated by sIUD compared with those that were not (32.0 weeks: interquartile range (IQR), 29.0–34.3 weeks vs 36.7 weeks: IQR, 35.0–37.6; P < 0.001) and this difference persisted when stratifying the data according to chorionicity (P < 0.0001 for both MC and DC pregnancies). The risk of PTB at < 34 weeks (RR, 4.3 (95% CI, 3.5–5.2)), < 32 weeks (RR, 6.1 (95% CI, 4.6–8.1)) and < 28 weeks (RR, 12.4 (95% CI, 6.9–22.2)) of gestation was higher in pregnancies complicated by sIUD compared with those which did not experience fetal loss. This association was observed both in MC and DC twin gestations. When compared with DC pregnancies, MC twins affected by sIUD were not at significantly increased risk of PTB before either 34, 32 or 28 weeks of gestation. The risk of PTB at < 34 weeks of gestation was higher when the sIUD occurred at a later gestational age (chi‐square test for trend, P < 0.001).ConclusionsTwin pregnancies complicated by sIUD, regardless of the chorionicity, have a significantly higher risk of PTB at < 34, < 32 and < 28 weeks of gestation. The risk of PTB at < 34 weeks of gestation was higher when the sIUD occurred in the second half of the pregnancy. Large prospective multicenter studies with shared protocols for prenatal management are needed to ascertain the actual risk of spontaneous PTB in twin pregnancies affected by sIUD. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Technical note: Option‐based costing and the volatility portfolio
Authors: de Treville Suzanne , Cattani Kyle , Saarinen Lauri 
Published: February 2017

AbstractIt has been clearly established that a cost premium for responsiveness may be justified for profitable time‐sensitive products, and that this cost premium may suffice to render production in a high‐cost environment competitive. Time‐insensitive products considered in isolation seldom justify a cost premium, leading many decision makers to conclude that their production does not belong in a high‐cost environment. This leads to a manufacturing‐location decision in which profitable and time‐sensitive products are produced in a high‐cost environment and time‐insensitive products are transferred to a low‐cost environment. Responsiveness, however, requires a capacity buffer that provides the option to meet a demand peak for a profitable, time‐sensitive product. Leftover capacity can then be ideally deployed to manufacture time‐insensitive products to stock. We propose that the cost of the capacity buffer be considered as an option cost and assigned to the time‐sensitive product: “option‐based costing”. We then demonstrate use of demand volatility to create a portfolio of products that are time sensitive and insensitive to generate profit and increase competitiveness. Option‐based costing combined with a volatility portfolio reveals opportunities to produce competitively in high‐cost environments that have typically been considered unfeasible.
Echocardiography of coarctation of the aorta, aortic arch hypoplasia, and arch interruption: strategies for evaluation of the aortic arch
Authors: Goudar Suma P. , Shah Sanket S. , Shirali Girish S. 
Published: February 2017

AimEchocardiography is the modality of choice for the diagnosis and serial follow-up of aortic arch pathology. In this article, we review the types of obstruction of the aortic arch, various classification schemes of coarctation of the aorta and interrupted aortic arch, methodology for optimal echocardiographic imaging of the aortic arch, and key echocardiographic measurements for accurate diagnosis of obstruction and hypoplasia of the aortic arch. Finally, we will discuss the limitations of echocardiography in optimal imaging of the aortic arch and the use of other non-invasive imaging modalities such as CT or MRI to provide additional information in these cases.BackgroundCoarctation of the aorta is the more common lesion of the two, with an estimated incidence of four in every 10,000 live births in the United States of America. Interrupted aortic arch is rarer, with an incidence of 19 per one million live births.1 There is a spectrum of pathology of obstruction of the aortic arch, ranging from coarctation of the aorta with and without hypoplasia of the arch to interrupted aortic arch. Both these lesions are frequently encountered in congenital cardiology practice, and will be discussed in the remainder of this article. Obstruction of the aortic arch in the setting of hypoplastic left heart structures or atresia of the aortic valve is beyond the scope of this review and will not be discussed further.
The use of a three-dimensional print model of an aortic arch to plan a complex percutaneous intervention in a patient with coarctation of the aorta
Authors: Ghisiawan Nalini , Herbert Carrie E. , Zussman Matthew , Verigan Adam , Stapleton Gary E. 
Published: February 2017

AbstractRecently, three-dimensional printing of heart models is being used to plan percutaneous and surgical interventions in patients with CHD. We describe a case where we used a three-dimensional print model to plan a complex percutaneous intervention in a patient with coarctation of the aorta.
Oral Function Improves Interfacial Integrity and Sealing Ability Between Conventional Glass Ionomer Cements and Dentin
Authors: Toledano Manuel , Osorio Raquel , Cabello Inmaculada , Osorio Estrella , Toledano-Osorio Manuel , Aguilera Fátima S. 
Published: February 2017

AbstractThe aim of this study was to investigate if load cycling affects interfacial integrity of glass ionomer cements bonded to sound- or caries-affected dentin. A conventional glass ionomer, Ketac Bond, and a resin-modified glass ionomer (Vitrebond Plus), were applied to dentin. Half of the specimens were load cycled. The interfaces were submitted to dye-assisted confocal microscopy evaluation. The unloaded specimens of sound and carious dentin were deficiently hybridized when Ketac Bond was used. Ketac Bond samples showed an absorption layer and an adhesive layer that were scarcely affected by fluorescein penetration (nanoleakage), in sound dentin. Nevertheless, a higher degree of micropermeability was found in carious dentin. In Ketac Bond specimens, load cycling improves the sealing capability and remineralization at the cement–dentin interface as porosity and nanoleakage was reduced. In contrast, samples treated with Vitrebond Plus exhibited a Rhodamine B-labeled absorption layer with scarce nanoleakage in both sound and carious unloaded dentin. The adhesive layer was affected by dye sorption throughout the porous cement–dentin interface. Samples treated with Vitrebond Plus had significant increases in nanoleakage and cement–dye sorption after load cycling. Within the limitations of an in vitro study, it is expected that conventional glass ionomers will provide major clinical efficacy when applied to carious-affected or sound dentin.