bluuebunny/crossref_metadata_2025_split huggingface dataset:
Process-related value propositions of enterprise social media use for the external communication with end consumers
Authors: Johannsen Florian Andreas 
Published: December 2017

Purpose
The purpose of this paper is to identify process-related value propositions in terms of process execution when using enterprise social media (ESM) for external communication purposes. Additionally, capabilities of ESM technologies to realize the value propositions are identified.

Design/methodology/approach
A literature review of case studies, describing ESM usage for external communication purposes, is performed. Further, face-to-face interviews with employees from companies are conducted to complement the findings retrieved from the literature.

Findings
It is shown that manifold process-related value propositions for different business processes can be realized by ESM application for external communication purposes. However, certain value propositions and the corresponding capabilities of ESM technologies are particularly emphasized.

Research limitations/implications
This research is different from existing studies about ESM usage because an explicit perspective on business processes is taken. Therefore, the findings contribute to the existing body of knowledge of beneficial ESM usage. Analyzing the literature and interview transcripts underlies a certain amount of subjectivity, a circumstance addressed by engaging two researchers in the coding procedure.

Practical implications
Practitioners discussing potentials of ESM application are provided with concrete hints as to which business processes will most likely profit from the use of social technologies for the external communication with customers.

Originality/value
This paper contributes to a better understanding of the beneficial impact of social technologies on business processes and thus prepares the ground for a better alignment of ESM and processes. An extensive overview of value propositions for a company’s business processes has so far not been compiled in this form.
What drives a salesperson’s goal achievement? An empirical examination
Authors: Kumar V. , Goreczny Ashley , Maurer Todd 
Published: December 2017

PurposeThe purpose of this study is to understand how a salesperson’s preset goals, customer satisfaction levels and past performance affect the extent of goal achievement, as well as how job-specific attitudes and emotions affect the relationship between preset goals and goal achievement.Design/methodology/approachThis study uses a modeling framework with both main, moderating and mediating effects, using transaction data and survey results from a telecommunications firm.FindingsThe results indicate that preset goals and customer satisfaction, interestingly, have an inverted-U relationships with goal achievement. Further, attitudes and emotions regarding workplace conduciveness and workplace ethics and diversity, reduce the effect preset goals have on goal achievement. However, attitudes and emotions regarding workplace philosophy strengthens the effect preset goals have on goal achievement, whereas with disagreement, this relationship diminishes.Research limitations/implicationsTwo of the primary limitations of this study are: one, because of the cross-sectional nature of the study, there is limited opportunity to control for unobserved heterogeneity; and two, performance goal achievement, though is important for the firm, is one of many potential goals that affect a salesperson. For example, customer satisfaction goals or a one-time special event goals could play a role. Therefore, only using performance goal achievement could be a limitation of this study.Originality/valueThis study contributes to academic literature in three ways. First, it demonstrates the diminishing effect of customer satisfaction on goal achievement. Second, it identifies an inverse U-shaped relationship between preset goals and goal achievement. Finally, it examines how attitudes and emotions regarding workplace culture (conduciveness, ethics and diversity and philosophy) affect the relationship between preset goals and goal achievement.
Three generational issues in organizational learning
Authors: Sprinkle Therese A. , Urick Michael J. 
Published: December 2017

Purpose
Methods for facilitating learning and knowledge transfer in multigenerational workplaces are of importance to organizations. Yet, intergenerational learning is vastly understudied in academic organizational literature. This conceptual paper aims to recommend future directions for studying intergenerational learning by examining three interrelated considerations.

Design/methodology/approach
General knowledge management concepts, various generationally based perspectives on training and low-stakes development initiatives, are examined by integrating the existing literature.

Findings
The authors suggest that improved learning will occur in organizations that facilitate targeted socialization, respond to new preferences and trends in development programs while leveraging multiple approaches including informal/individualized initiatives (such as on-the-job education, mentorship programs) and embrace multiple types of volunteering activities.

Originality value
Although other work has reviewed intergenerational learning, this is the first research to focus on multigenerational learning while considering tacit and practical learning transference from inside and outside the organization.
CoPs facing rationalization: the politics of community reproduction
Authors: Kilskar Stine Skaufel , Ingvaldsen Jonas A. , Valle Nina 
Published: December 2017

Purpose
This paper aims to explore the relationship between the contemporary forms of manufacturing rationalization and the reproduction of communities of practice (CoPs) centred on tasks and craft. Building on critical literature highlighting the tensions between CoPs and rationalization, this paper aims to develop a nuanced account of how CoPs are reproduced in the context of rationalization.

Design/methodology/approach
A qualitative case study of a CoP involved in the production of automotive components was conducted. Following a change in ownership, the company was instructed to rationalize production according to the principles of lean production. Data were collected through participant observation and semi-structured interviews.

Findings
The CoP of the case study reinterpreted, resisted and redefined the lean production practices according to the established norms and values. In collusion with local management, workers protected the integrity of the community by engaging in hypocritical reporting. While lower-level managers buffered the rationalization pressures, workers would “get the work done” without further interference.

Research limitations/implications
The critical research approach may be applied to a wide range of cases in which informal or professional work organization collides with change programmes driven by management. Future research is encouraged to investigate more closely how CoPs gain access to formal and informal power by enrolling lower-level managers in their joint enterprise and world view.

Practical implications
Managers should be aware that attempts to rationalize community-based work forms may lead to dysfunctional patterns of organizational decoupling.

Originality/value
This study is one of the first to empirically examine the relationship between CoPs and manufacturing rationalization.
The effects of spatial scale and isoscape on consumer isotopic niche width
Authors: Reddin Carl J. , Bothwell John H. , O'Connor Nessa E. , Harrod Chris 
Published: December 2017

Abstract

The mean and variance of ecological variables are dependent on sampling attributes such as the coverage of environmental heterogeneity (sampling extent) and spatial scale. Trophic niche width is often approximated by bulk tissue stable isotopes of C and N, that is, the population isotopic niche. However, recent studies suggest that environmental heterogeneity (experienced by individuals) may be more important in defining the isotopic niche width than trophic variability. We hypothesised that isotopic niche width will increase monotonically with spatial scale, largely produced by environmental variation, for example, nutrient source.

To refine this hypothesis, by describing the shapes of isotope scaling curves, we explored a previously published dataset describing three Chilean intertidal species representing different feeding guilds (grazing snails, suspension‐feeding mussel). We tested these hypotheses on a new, larger dataset describing three functionally analogous intertidal species from Northern Ireland. We generated isotopic variance–area curves from a spatially explicit bootstrap and investigated the scale dependency of environment–isotope relationships, including wave exposure and sub‐habitat heterogeneity.

Spatial scale explained 50% of the variance in population isotopic niche widths (bivariate C‐N ellipse area) by simple, nonlinear relationships. Finer scales (<1–10 km lag) accounted for most variance. Scale dependence was strong for δ15N variance, of which >40% was explained by modelling linear coefficients. A δ15N baseline gradient, or isoscape, dominated δ15N variance scaling patterns, from sheltered, terrestrially influenced embayments to exposed, pelagic‐dominated coastline. Consumer δ13C variance had a weaker scale dependence, plateauing at mesoscales (>20 km lag).

We show that isotopic niche width is strongly dependent on sampling spatial extent, which controls the environmental heterogeneity experienced by individual consumers. Environmental heterogeneity must be accounted for before isotopic niche width can be considered to accurately represent trophic niche width. Studies conducted at different spatial scales are likely to identify different environment–isotope relationships.

We recommend that spatial scale should be incorporated into sampling designs explicitly, easiest by maintaining a consistent lag distance or area within which populations are sampled. Identified isoscapes can be de‐trended, where necessary.

A plain language summary is available for this article.
Editorial: thiopurine‐induced myelosuppression and infections in inflammatory bowel disease patients with a normal TPMT genotype—the perils of ageing
Authors: Willington A. J. , Gearry R. B. 
Published: December 2017

Linked ContentThis article is linked to Broekman et al papers. To view these articles visit https://doi.org/10.1111/apt.14323 and https://doi.org/10.1111/apt.14395.
Editorial: recurrence of Helicobacter pylori infection—still the same after all these years… Authors’ reply
Authors: Hu Y. , Wan J.‐H. , Li X.‐Y. , Zhu Y. , Graham D. Y. , Lu N.‐H. 
Published: December 2017

Linked ContentThis article is linked to Hu et al and Shah and Chey papers. To view these articles visit https://doi.org/10.1111/apt.14319 and https://doi.org/10.1111/apt.14372.
Letter: the neglected analgesic properties of red pepper in the clinical management of the irritable bowel syndrome pain—Authors’ reply
Authors: Beckers A. B. , Weerts Z. Z. R. M. , Masclee A. A. M. , Keszthelyi D. 
Published: December 2017

Linked ContentThis article is linked to Beckers et al and Bortolotti papers. To view these articles visit https://doi.org/10.1111/apt.14294 and https://doi.org/10.1111/apt.14417.
Anti‐infliximab antibody concentrations can guide treatment intensification in patients with Crohn's disease who lose clinical response
Authors: Dreesen E. , Van Stappen T. , Ballet V. , Peeters M. , Compernolle G. , Tops S. , Van Steen K. , Van Assche G. , Ferrante M. , Vermeire S. , Gils A. 
Published: December 2017

SummaryBackgroundThe presence of antibodies towards infliximab (ATI) is associated with lower infliximab (IFX) trough concentrations and loss of response. IFX treatment intensification is effective for restoring response in most, but not all patients with Crohn's disease (CD).AimTo compare outcome, pharmacokinetics and immunogenicity of treatment intensification strategies in patients with CD who lost clinical response to IFX.MethodsA retrospective cohort study was conducted, including 103 patients with CD who lost clinical response during IFX maintenance therapy and therefore received a double dose IFX (10 mg/kg) and/or a next infusion after a shortened interval. IFX and ATI concentrations were measured in consecutive trough samples, just before (T0) and after (T+1) treatment intensification.ResultsClinical response (physicians' global assessment) and biological response and remission (CRP) were restored in 63%, 42% and 24% of patients (evaluated at T+1). Treatment intensification increased IFX trough concentrations from 1.2 μg/mL [0.3‐3.6] at T0 to 3.6 μg/mL [0.5‐10.2] at T+1 (P < .0001). Using a drug tolerant assay, ATI were detected in the T0 sample of 47% of patients. ATI negatively impacted the achieved IFX trough concentration (Spearman r −0.57, P < .0001) and the probability of clinical response (P = 0.034) at T+1. When ATI were quantifiable but <282 ng/mL eq. at T0, combined interval shortening and dose doubling was more effective for restoring therapeutic IFX trough concentrations (≥3 μg/mL at T+1) than dose doubling alone, which in turn was more effective than interval shortening alone (P < .001).ConclusionAntibodies towards infliximab can guide clinical decision‐making on treatment intensification.
Effect of abutment height on interproximal implant bone level in the early healing: A randomized clinical trial
Authors: Blanco Juan , Pico Alexandre , Caneiro Leticia , Nóvoa Lourdes , Batalla Pilar , Martín‐Lancharro Pablo 
Published: December 2017

AbstractObjectiveThe aim of this randomized clinical trial was to compare the effect on the interproximal implant bone loss (IBL) of two different heights (1 and 3 mm) of definitive abutments placed at bone level implants with a platform switched design.Material and methodsTwenty‐two patients received forty‐four implants (6.5–10 mm length and 3.5–4 mm diameter) to replace at least two adjacent missing teeth, one bridge set to each patient—two implants per bridge. Patients were randomly allocated, and two different abutment heights, 1 and 3 mm using only one abutment height per bridge, were used. Clinical and radiological measurements were performed at 3 and 6 months after surgery. Interproximal bone level changes were compared between treatment groups. The association between IBL and categorical variables (history of periodontitis, smoking, implant location, implant diameter, implant length, insertion torque, width of keratinized mucosa, bone density, gingival biotype and antagonist) was also performed.ResultsAt 3 months, implants with a 1‐mm abutment had significantly greater IBL (0.83 ± 0.19 mm) compared to implants with a 3‐mm abutment (0.14 ± 0.08 mm). At 6 months, a greater IBL was observed at implants with 1‐mm abutments compared to implants with 3‐mm abutments (0.91 ± 0.19 vs. 0.11 ± 0.09 mm). The analysis of the relation between patient characteristics and clinical variables with IBL revealed no significant differences at any moment except for smoking.ConclusionsAbutment height is an important factor to maintain interproximal implant bone level in early healing. Short abutments led to a greater interproximal bone loss in comparison with long abutments after 6 months. Other variables except smoking showed no relation with interproximal bone loss in early healing.
Hochdosierte intravenöse Immunglobuline bei dermatologischen Autoimmunerkrankungen
Authors: Hoffmann Jochen H.O. , Enk Alexander H. 
Published: December 2017

ZusammenfassungHochdosierte intravenöse Immunglobuline (IVIg) werden aufgrund ihrer immunmodulatorischen Eigenschaften erfolgreich zur Behandlung dermatologischer Autoimmunkrankheiten eingesetzt. Hierbei stellen der Pemphigus vulgaris und die Dermatomyositis klassische Indikationen dar. Bei den bullösen Autoimmundermatosen kann der adjuvante Einsatz von IVIg als Zweit‐ oder Drittlinientherapie nach Versagen einer kombinierten immunsuppressiven Therapie erfolgen, während in der Behandlung der Dermatomyositis IVIg bereits als adjuvante Zweitlinientherapie nach Versagen einer Steroidmonotherapie eingesetzt werden können. Aufgrund mangelnder Therapiealternativen können IVIg bei schweren Verläufen des Skleromyxödems als Erstlinientherapie eingesetzt werden. In therapierefraktären Fällen einer schweren systemischen Vaskulitis kann die Anwendung von IVIg erwogen werden. Ebenso stellen schwere Fälle eines systemischen Lupus erythematodes eine mögliche Indikation zum Einsatz von IVIg dar. Auch zur Behandlung der toxischen epidermalen Nekrolyse können IVIg bei frühzeitigem und hochdosiertem Einsatz indiziert sein. Häufigere, gut zu behandelnde Nebenwirkungen stellen Kopfschmerzen, Übelkeit, Fatigue und eine febrile Infusionsreaktion dar. Sehr selten kommt es zum Auftreten schwerer Nebenwirkungen wie thromboembolischen Ereignissen, anaphylaktischem Schock oder akutem Nierenversagen. Das Risiko einer viralen Transmission ist sehr gering. Hypothesen zur Wirkweise sind die Hochregulation inhibitorischer Fc‐Rezeptoren, eine reduzierte Halbwertszeit von körpereigenen Immunglobulinen durch Verdrängung aus protektiven Rezeptorbindungen, die direkte Neutralisierung körpereigener Antikörper durch antiidiotypische Antikörper, sowie die Inhibierung der Komplementkaskade.
Atrial deformation correlated with functional capacity in mitral stenosis patients
Authors: Chien Chen‐Yu , Chen Chih‐Wei , Lin Tin‐Kwang , Lin Yu , Lin Jnnu‐Wen , Li Yi‐Da , Chen Chi‐Hsien , Tsai Wei‐Chuan 
Published: December 2017

BackgroundLeft atrial (LA) dysfunction, expressed as impaired LA deformation using two‐dimensional (2D) strain imaging, has been observed in association with rheumatic mitral stenosis (MS). However, the clinical role of speckle tracking echocardiography (STE)‐derived LA strain has rarely been studied in MS.AimThis study aimed to identify the determinants of New York Heart Association (NYHA) functional class in patients with mitral stenosis and to investigate the relationship between left atrial deformation as measured by two‐dimensional STE‐derived LA strain and heart failure symptoms.MethodsSixty‐nine consecutive patients (20 males and 49 females; mean age: 61 ± 14 years) with rheumatic MS were evaluated using comprehensive 2D and color Doppler echocardiography including STE‐derived LA strain (LAS) and peak positive filling strain rate (LASRr) during the LA reservoir phase. Those results were then correlated with NYHA functional class.ResultsThere were 15 (22%) patients in functional class I, 42 (61%) in functional class II, and 12 (17%) in functional class III. There were no significant differences in mitral valve area, pressure gradient, pulmonary artery pressure, LA emptying fraction, or left ventricular ejection fraction between functional classes. Upon multivariate analysis (controlling for diuretics usage), LAS (ß = −0.233, P = .045) and LASRr (ß = −0.277, P = .014) were independent factors in determining NYHA functional class.ConclusionsIn stable patients with MS, NYHA functional class independently correlated with LAS and LASRr. Left atrial (LA) deformation correlated with heart failure symptoms in patients with MS.
Two‐ and three‐dimensional transthoracic echocardiographic assessment of superior vena cava, crista terminalis, and right atrial appendage using the right parasternal approach
Authors: Arisha Mohammed J. , Hsiung Ming C. , Nanda Navin C. , Gupta Ankur , George David C. , Elkaryoni Ahmed , Barssoum Kirolos , Mohamed Ahmed H. , Srialluri Swetha 
Published: December 2017

BackgroundThe noninvasive assessment of superior vena cava (SVC), crista terminalis (CT), and the right atrial appendage (RAA) has clinical implications in determining the right atrium (RA) pressure in adult patients in whom the inferior vena cava cannot be imaged, in planning electrophysiological procedures and for evaluation of thrombi in RA/RAA. It is difficult to image these structures using standard two‐dimensional transthoracic echocardiography (2DTTE), but the right parasternal approach has shown promise in the very few studies published so far.AimThe aim of this study was to show the feasibility of this approach and its usefulness in qualitative and quantitative assessments of these structures by both 2D and three (3D) TTE in patients with and without known cardiac pathologies.Material and MethodsThe study consisted of 38 adult patients, 17 of whom had cardiac pathologies (Group 1) while the remainder (Group 2) had no evidence of heart disease clinically or by echocardiography.Results and ConclusionBoth SVC and RAA could be imaged by 2DTTE and 3DTTE in 53% of 40 patients (two separate groups of 20 consecutive patients) studied demonstrating the technical feasibility of this approach. SVC size and collapsibility, CT and RAA size, and RAA fractional shortening were evaluated in both groups by both 2D and 3DTTE. 3DTTE provided incremental value over 2DTTE by its ability to view en face the SVC in short axis and the base of RAA and RAA volumes resulting in more comprehensive assessment of their size and function.
The effect of dialysis type on left atrial functions in patients with end‐stage renal failure: A propensity score‐matched analysis
Authors: Aksu Uğur , Aksu Derya , Gulcu Oktay , Kalkan Kamuran , Topcu Selim , Aksakal Enbiya , Aksakal Emrah , Sevimli Serdar , Tanboga Ibrahim Halil 
Published: December 2017

IntroductionDespite the widespread use of both hemodialysis (HD) and peritoneal dialysis (PD), there is no study comparing the effects of these dialysis methods on the left atrial (LA) volume and functions. In this study, we investigated the impact of different dialysis methods on the LA volume and function in the patients exposed to chronic pressure overload and volume overload.MethodThis study was carried out on the patients who received dialysis treatment at our healthcare center between March, 2015 and January, 2016. Twenty‐eight patients receiving hemodialysis (HD) treatment and 24 patients under PD treatment were enrolled into the study. Patients were divided into 2 groups according to the dialysis therapy, and the atrial volumetric and mechanical functions were investigated.ResultsAs the basal demographical characteristics of patients in the PD and HD groups were significantly different, 44 patients matched on a 1:1 basis were taken for final analysis (22 HD, 22 PD, and the average age of 42.4 ± 4.8; 73% was male). After propensity score matching analysis, it was determined that left atrial volume index (LAVi) was higher in the HD group while peak LA strain and LA contraction strain were higher in the PD group. Additionally, both strain parameters showed a good negative correlation with LAVi.ConclusionWe demonstrated that the left atrial structure and functions were better in the PD group suggesting that PD may be a relatively better option for the preservation and maintenance of the left atrial functions as compared to HD.
The information content of the implied volatility term structure on future returns
Authors: Wang Yaw‐Huei , Yen Kuang‐Chieh 
Published: December 2017

AbstractWe derive the theoretical relation between the term structure of implied variance and the expected excess returns of the underlying asset. Adopting three alternative approaches to compile the variables representing the information on the implied volatility index level and term structure, we show the important role of the term structure in determining future excess returns of the S&P 500 index. Both the in‐sample and out‐of‐sample analyses suggest that the information content of the term structure variable is significant and a strong complement to that of the level variable, especially for shorter‐term excess returns.