bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of event characteristics on assessing credibility and advice-taking
Authors: Johnson Hana Huang , Johnson Michael D. 
Published: February 2017

PurposeThe purpose of this paper is to examine how the environment surrounding a decision-making event affects whether decision-makers consider the credibility of their advisors and take their advice.Design/methodology/approachIn two experiments, the characteristics of the event and credibility of the advisor were manipulated, the extent to which participants considered the information from the advisor was measured, and whether participants took advice was determined.FindingsDecision-makers are more likely to take advice from advisors when the decision-making event is of low urgency or high criticality because they are more likely to consider information provided by high-credibility advisors.Practical implicationsWithin organizations, decision-makers may be making suboptimal decisions when faced with highly urgent decisions or decisions with low criticality. This study suggests that under these conditions, decision-makers are less likely to consider the information provided by high-credibility advisors. Organizations may consider encouraging decision-makers to override their tendency to disregard advice from credible advisors.Originality/valueThis study introduces a contextual factor relevant to managers, event characteristics, which has an effect on whether decision-makers take advice. A unique experimental design was utilized in which credibility was manipulated across two studies with an explicit (Study 1: resume) vs implicit (Study 2: video) method, and advice-taking was measured with a decision that was clearly right or wrong.
Markets and market boundaries: a social practice approach
Authors: Gosling Martyn , Richard James , Seo Yuri 
Published: February 2017

Purpose
The paper contributes to the debate on a general theory of markets. The purpose of this paper is to develop a market practice model based on social practice theories, and explore new ways of describing market boundaries.

Design/methodology/approach
A conceptual analysis of contemporary marketing directions and market theorizations provides a basis for defining markets and market boundaries in terms of social practices and their performances by market actors.

Findings
Based on the market performances held in place by institutional practices that define, contextualize and stabilize a market, this paper defines market boundaries by nine specific categories of practices, described here as parameters.

Research limitations/implications
This is a conceptual paper. Future research using empirical evidence derived from situated investigations should endeavor to refine the model and practices that define market boundaries.

Originality/value
The paper provides a new conceptualization of markets and market boundaries from the social practice perspective, and advances contemporary market theorizing that puts services at the center of exchange. The paper offers managerial implications by describing alternative means for analyzing markets and developing corresponding competitive strategies. Furthermore, the conception of market boundaries as nine parameters provides insights beyond the geographic and price boundaries typically used to describe market limits and exchange processes when developing policy.
Consumer construal of separation in virtual services
Authors: Hartley Nicole , Green Teegan 
Published: February 2017

Purpose
Service encounters are becoming increasingly virtual through the infusion of computer-mediated technologies. Virtual services separate consumers and service providers both spatially and temporally. With the advent of virtual services is the need to theoretically explain how service separability is psychologically perceived by consumers across the spectrum of computer-mediated technologies. Drawing on construal-level theory, the purpose of this paper is to conceptualize a theoretical framework depicting consumer’s construal of spatial and temporal separation across a continuum of technology-mediated service virtuality.

Design/methodology/approach
The authors conducted two studies: first, to investigate consumers’ levels of mental construal associated with varying degrees of service separation across a spectrum of technology-mediated services; second, to empirically examine consumer evaluations of service quality in response to varying degrees of spatial and temporal service separation. These relationships were tested across two service industries: education and tourism.

Findings
Consumers mentally construe psychological distance in response to service separation and these observations vary across the spectrum of service offerings ranging from face-to-face (no psychological distance) through to virtual (spatially and temporally separated – high psychological distance) services. Further, spatial separation negatively affects consumers’ service evaluations; such that as service separation increases, consumers’ service evaluations decrease. No such significant findings support the similar effect of temporal separation on customer service evaluations. Moreover, specific service industry-based distances exist such that consumers responded differentially for a credence (education) vs an experiential (tourism) service.

Originality/value
Recent studies in services marketing have challenged the inseparability assumption inherent for services. This paper builds on this knowledge and is the first to integrate literature on construal-level theory, service separability, and virtual services into a holistic conceptual framework which explains variance in consumer evaluations of separated service encounters. This is important due to the increasingly virtual nature of service provider-customer interactions across a diverse range of service industries (i.e. banking and finance, tourism, education, and health care). Service providers must be cognisant of the psychological barriers which are imposed by increased technology infusion in virtual services.
Syntrophobacteraceae‐affiliated species are major propionate‐degrading sulfate reducers in paddy soil
Authors: Liu Pengfei , Conrad Ralf 
Published: February 2017

SummaryMethane is an important greenhouse gas and propionate is next to acetate the main intermediate (average 23%) of the carbon flow to CH4 in paddy fields. Sulfate (e.g., gypsum) application can reduce CH4 emissions up to 70%. However, the effect of gypsum application on propionate degradation and the microbial communities involved are not well understood. Therefore, we studied propionate‐dependent sulfate reduction in anoxic microcosms of paddy soils from Italy and the Philippines, combining 16S rRNA and dissimilatory sulfite reductase (dsrB) gene profiling and co‐occurrence network analysis. Sulfate was stoichiometrically reduced in treatments with propionate addition, while CH4 production was partially suppressed. Methane production but not sulfate reduction were suppressed and acetate accumulated after addition of methyl fluoride or fluoroacetate. With methyl fluoride in the presence of sulfate, the accumulated acetate was consumed after the depletion of propionate. Simultaneously, the relative abundances of Syntrophobacteraceae and Desulfovibrionaceae were significantly enhanced, while fluoroacetate repressed Desulfobulbaceae in both soils. Syntrophobacter 16S rRNA and dsrB gene copy numbers were also remarkably increased with gypsum amendment. Network analysis of both 16S rRNA and dsrB genes illustrated a strong co‐occurrence of operational taxonomic units belonging to Syntrophobacteraceae, Desulfovibrionaceae and Desulfobulbaceae. In summary, Syntrophobacteraceae affiliated species were identified as the major propionate‐dependent sulfate reducers in paddy soil. They (together with Desulfobulbaceae) oxidized propionate directly to acetate and CO2, or coupled the oxidation syntrophically to H2/formate‐utilizing Desulfovibrionaceae. The transiently accumulating acetate was preferentially consumed by acetoclastic Methanosarcinaceae.
Overexpression of pregnane X and glucocorticoid receptors and the regulation of cytochrome P450 in human epileptic brain endothelial cells
Authors: Ghosh Chaitali , Hossain Mohammed , Solanki Jesal , Najm Imad M. , Marchi Nicola , Janigro Damir 
Published: February 2017

SummaryObjectiveRecent evidence suggests a metabolic contribution of cytochrome P450 enzymes (CYPs) to the drug‐resistant phenotype in human epilepsy. However, the upstream molecular regulators of CYP in the epileptic brain remain understudied. We therefore investigated the expression and function of pregnane xenobiotic (PXR) and glucocorticoid (GR) nuclear receptors in endothelial cells established from post‐epilepsy surgery brain samples.MethodsPXR/GR localization was evaluated by immunohistochemistry in specimens from subjects who underwent temporal lobe resections to relieve drug‐resistant seizures. We used primary cultures of endothelial cells obtained from epileptic brain tissues (EPI‐ECs; n = 8), commercially available human brain microvascular endothelial cells (HBMECs; n = 8), and human hepatocytes (n = 3). PXR/GR messenger RNA (mRNA) levels in brain ECs was initially determined by complementary DNA (cDNA) microarrays. The expression of PXR/GR proteins was quantified by Western blot. PXR and GR silencing was performed in EPI‐ECs (n = 4), and the impact on downstream CYP expression was determined.ResultsPXR/GR expression was detected by immunofluorescence in ECs and neurons in the human temporal lobe samples analyzed. Elevated mRNA and protein levels of PXR and GR were found in EPI‐ECs versus control HBMECs. Hepatocytes, used as a positive control, displayed the highest levels of PXR/GR expression. We confirmed expression of PXR/GR in cytoplasmic‐nuclear subcellular fractions, with a significant increase of PXR/GR in EPI‐ECs versus controls. CYP3A4, CYP2C9, and CYP2E1 were overexpressed in EPI‐ECs versus control, whereas CYP2D6 and CYP2C19 were downregulated or absent in EPI‐ECs. GR silencing in EPI‐ECs led to decreased CYP3A4, CYP2C9, and PXR expression. PXR silencing in EPI‐ECs resulted in the specific downregulation of CYP3A4 expression.SignificanceOur results indicate increased PXR and GR in primary ECs derived from human epileptic brains. PXR or GR may be responsible for a local drug brain metabolism sustained by abnormal CYP regulation.
Inhibition of transient receptor potential vanilloid‐1 confers neuroprotection, reduces tumor necrosis factor‐alpha, and increases IL‐10 in a rat stroke model
Authors: Hakimizadeh Elham , Shamsizadeh Ali , Roohbakhsh Ali , Arababadi Mohammad Kazemi , Hajizadeh Mohammad R. , Shariati Mehdi , Rahmani Mohammad R. , Allahtavakoli Mohammad 
Published: February 2017

AbstractStroke is a major cause of mortality and long‐term disability in adults. Transient receptor potential vanilloid‐1 (TRPV1) plays a crucial role in neuroinflammation. In this study, the effects of TRPV1 agonist (capsaicin) and antagonist (AMG9810) on cerebral ischemia were investigated. Forty male Wistar rats were assigned to the following experimental groups: sham, vehicle) ischemic), AMG9810 (selective TRPV1 antagonist, 0.5 mg/kg; 3 h after stroke), and capsaicin (1 mg/kg; 3 h after stroke). Stroke was induced by permanent middle cerebral artery occlusion and neurological deficits were evaluated 1, 3, and 7 days after stroke. Then, infarct volume, brain edema, body temperature, mRNA expression of TRPV1, and serum concentrations of tumor necrosis factor‐alpha (TNF‐α) and IL‐10 were measured. Compared to the vehicle group, AMG9810 significantly decreased the infarct volume (P < 0.01). Latency for the removal of sticky labels from the forepaw and the hanging time were significantly decreased and increased, respectively, following administration of AMG9810 (P < 0.01 and P < 0.001 vs. vehicle) 3 and 7 days after stroke. Compared to the sham group, the mRNA expression of TRPV1 was significantly increased in vehicle group (P < 0.01). Administration of AMG9810 significantly increased the anti‐inflammatory cytokine IL‐10 and decreased the inflammatory cytokine TNF‐α (P < 0.05). Moreover, our results indicate that AMG9810 might a promising candidate for the hypothermic treatment of stroke. The findings also suggest a key role for AMG9810 in reducing inflammation after stroke and imply that TRPV1 could be a potential target for the treatment of ischemic stroke.
A study of fatigue crack growth from artificial corrosion pits at welded joints under complex stress fields
Authors: Jie Z. Y. , Li Y. D. , Wei X. 
Published: February 2017

AbstractThe paper studies the effects of artificial corrosion pits and complex stress fields on the fatigue crack growth of full penetration load‐carrying fillet cruciform welded joints with 45° inclined angle. Parameters of fatigue crack growth rate of welded joints are obtained from S‐N curves under different levels of corrosion. A numerical method is used to simulate fatigue crack growth using different mixed mode fatigue crack growth criteria. Using polynomial regression, the crack shape correction factor of welded joints is fitted as a function of crack depth ratios. Because the maximum circumferential stress criterion is simple and easy to use in practice, fatigue crack growth rate is modified using this criterion. The relationship of effective stress intensity factor, crack growth angle and crack depth is studied under different corrosion levels. The simulated crack growth path obtained from the numerical method is compared with the actual crack growth path observed by fatigue tests. The results show that fatigue cracks do not initiate at the edge or bottom of pits but at the weld toes where the maximum stress occurs. The artificial corrosion pits have little effect on the effective stress intensity factor ranges and crack growth angle. The fatigue crack growth rates of welded joints with pits 1 and 2 are 1.15 times and 1.40 times larger than that of the welded joint with no pit, respectively. The simulated crack growth path agrees well with the actual one. The fatigue life prediction accuracy using the modified formulation is improved by about 18%. The crack shape correction factor obtained using the maximum circumferential stress criterion is recommended being used to calculate fatigue life.
Measuring FVIII activity of glycopegylated recombinant factor VIII, N8‐GP, with commercially available one‐stage clotting and chromogenic assay kits: a two‐centre study
Authors: Hillarp A. , Bowyer A. , Ezban M. , Persson P. , Kitchen S. 
Published: February 2017

IntroductionFactor VIII activity (FVIII:C) assays of samples containing glycoPEGylated recombinant FVIII such as turoctocog alfa pegol (N8‐GP) can be associated with differences in FVIII recovery in vitro between various one‐stage activated partial thromboplastin time (APTT)‐based clotting assays and some chromogenic assays. Careful validation and qualification of specific assays and conditions is therefore necessary for the assessment of FVIII:C in samples containing modified FVIII molecules.AimTo assess the ability of various one‐stage clotting and chromogenic FVIII:C assays to measure samples containing N8‐GP compared to unmodified recombinant FVIII (rFVIII) across two laboratory sites.MethodsFactor VIII activity in severe haemophilia A (HA) plasma spiked with a range of concentrations (from low, 0.20 IU mL−1, to high, 0.90 IU mL−1) of N8‐GP and rFVIII, was determined at two laboratory sites using 12 commercially available one‐stage clotting and chromogenic FVIII:C assays. Assays were performed using a plasma calibrator and different analysers.ResultsAcceptable N8‐GP recovery was observed in the low to high concentration samples tested using the majority of the tested APTT reagents with only one reagent causing a significant underestimation as compared to rFVIII. For the chromogenic assays, a slight overestimation was observed with some of the kits. Variability between the two laboratory sites are likely attributable to the use of different analysers with the respective APTT reagents.ConclusionsThese results highlight the need to investigate the performance of modified factor products using standard assays. The performance of different one‐stage clotting assays, APTT reagents, reference calibrators and instrumentation should also be evaluated.
Brooding sea anemones (Cnidaria: Anthozoa: Actiniaria): paragons of diversity in mode, morphology, and maternity
Authors: Larson Paul 
Published: February 2017

AbstractBrooding has been reported in at least 57 species of sea anemone. More than three quarters (44/57) of the species that are known to brood have been described since the last comprehensive treatment of brooding in this lineage. Different authors focusing on different taxonomic groups within sea anemones over the last 115 years have collectively produced an imprecise and inconsistent set of terminology with respect to brooding in general and to the variety of conditions of brooding in particular. In this review, I characterize brooding as a behavior in which offspring are retained by the adult to at least the juvenile stage, in contrast with the more common release of eggs, embryos, or larvae. Brooding occurs in two primary modes, internal and external, in which offspring may be produced via sexual or asexual means. I categorize structures associated with external brooding in three types: pits, chambers, and grooves. Early inferences that external brooding has a primarily bipolar distribution continue to be supported with current data, but it is doubtful that small size and simultaneous hermaphroditism are correlated with brooding in sea anemones. Finally, I identify open questions about brooding in sea anemones and suggest future lines of research that will broaden our understanding of this phenomenon.
Effect of photochemical UV/riboflavin‐mediated cross‐links on different properties of fish gelatin films
Authors: Wang Kun , Wang Wenhang , Wu Xiaomeng , Xiao Jingdong , Liu Yaowei , Liu Anjun 
Published: February 2017

AbstractThe use of riboflavin as photosensitizer in the UV irradiation induced cross‐linking process was studied to improve the properties of fish gelatin (FG) films. In the UV irradiation, the fluorescence spectroscopy results showed that cross‐linking occurred in the film at a riboflavin charge of 0.1% or higher and the viscosity of the FG solution increased as the riboflavin charge increased. The water contact angel of the fish gelatin film with the riboflavin mediated UV irradiation (RmUV) was significantly improved compared with the control FG films at 60 s. Moreover, compared with control FG films, water vapor absorption and water solubility of the RmUV radiated FG films both decreased. The tensile strength and Young's modulus of the RmUV radiated FG films were significantly higher than those of the control FG films whatever in dry or wet state. Based on the above results, the UV/riboflavin irradiation is a potential effective process to improve the performance of FG films.Practical applicationsIn the past decades, the extensive use of plastic packaging has led to increased concerns on plastic waste generated in daily life due to its nonbiodegradable and nonrenewable nature. For that reason, a variety of bio‐based materials including fish gelatin have been developed as environmentally friendly alternatives. The aim of this paper is to explore the potential application of the fish gelatin film with the riboflavin mediated UV irradiation (RmUV) in mainly food‐contacted packing material field. The use of riboflavin as photosensitizer in the UV irradiation induced cross‐linking in fish gelatin (FG) films, which subsequently improved the water resistance and strength properties of FG films. The findings in this study may serve as a platform to improve fish gelatin film performance and potentially extend applications of edible fish gelatin films in food industry.
Image scanning fluorescence emission difference microscopy based on a detector array
Authors: LI Y. , LIU S. , LIU D. , SUN S. , KUANG C. , DING Z. , LIU X. 
Published: February 2017

SummaryWe propose a novel imaging method that enables the enhancement of three‐dimensional resolution of confocal microscopy significantly and achieve experimentally a new fluorescence emission difference method for the first time, based on the parallel detection with a detector array. Following the principles of photon reassignment in image scanning microscopy, images captured by the detector array were arranged. And by selecting appropriate reassign patterns, the imaging result with enhanced resolution can be achieved with the method of fluorescence emission difference. Two specific methods are proposed in this paper, showing that the difference between an image scanning microscopy image and a confocal image will achieve an improvement of transverse resolution by approximately 43% compared with that in confocal microscopy, and the axial resolution can also be enhanced by at least 22% experimentally and 35% theoretically. Moreover, the methods presented in this paper can improve the lateral resolution by around 10% than fluorescence emission difference and 15% than Airyscan. The mechanism of our methods is verified by numerical simulations and experimental results, and it has significant potential in biomedical applications.
A national retrospective study of paediatric end‐stage liver disease as a predictor of change to second‐line therapy in children with autoimmune hepatitis
Authors: Zizzo Andréanne N. , Jimenez‐Rivera Carolina , Kim Joseph , Schreiber Richard A. , Ling Simon C. , Yap Jason , Critch Jeff , Ahmed Najma , Alvarez Fernando , Kamath Binita M. ,   The Canadian Paediatric Hepatology Research Group (CPHRG)
Published: February 2017

AbstractBackground & AimsAdult studies of autoimmune hepatitis (AIH) have shown that the model of end‐stage liver disease is associated with resistance to first‐line treatment. Using a multicentre retrospective database, we sought to determine if the paediatric end‐stage liver disease (PELD) score would similarly predict treatment resistance in paediatric AIH.MethodsOne hundred and seventy‐one children from 13 Canadian centres who fulfilled the International Autoimmune Hepatitis Group (IAIHG) criteria were included and assessed for change to second‐line therapy within 24 months of primary treatment onset. Those with PSC overlap at presentation, or missing data on the PELD variables were excluded. PELD was calculated for all remaining patients. Univariate analysis and receiver‐operator characteristic (ROC) curves were performed to determine the predictive ability of the PELD score to change to second‐line therapy.ResultsA total of 103 children were included with median age of 11 years (range 2‐17). Mean PELD was −2.51±8.58. Second‐line therapy was used within 24 months of diagnosis in 13 patients. Univariate analysis revealed that change to second‐line therapy was associated with higher PELD (P=.028) and internal normalized ratio (INR) (P=.011). ROC curves for PELD and its individual components were performed. The strength of association was strongest with INR (AUC 0.72; CI: 0.58‐0.86) although the composite PELD score also showed some predictive ability (AUC 0.67; CI: 0.52‐0.81).ConclusionIn this paediatric AIH cohort, higher PELD at presentation predicted change to second‐line therapy within the first 2 years of follow‐up. INR appeared to be the main contributor to that association.
Finance Sector Wage Growth and the Role of Human Capital
Authors: Lindley Joanne , Mcintosh Steven 
Published: February 2017

AbstractWe reveal the pervasiveness of the finance sector pay premium, across all OECD countries, as well as all sub‐sectors and occupations within the UK financial sector. Moreover, the UK premium has continued to rise despite the financial crisis. We show that earnings increase faster with value added in certain sub‐sectors of finance, compared to the general economy, providing evidence of profit‐sharing in these sub‐sectors. Other possible explanations, such as workers with higher qualifications or better cognitive skills, or technological change and differing job characteristics, can explain some of the finance sector pay premium, but are not sufficient on their own.