bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis with the Help of Digital Technology of Moments in Farms with and without Reinforcement Frame
Authors: Дегтярев Г.В. , Модар С. 
Published: September 2024

Постановка задачи. Рассматривается задача сравнительного анализа цифровыми технологиями моментов в фермах покрытия с каркасом и без каркаса усиления при исследовании параметров работы посредством математического анализа. Результаты. В результате применения цифровых технологий, при использовании метода конечных элементов, осуществлены расчеты моментов в фермах покрытия без каркаса и с каркасом. Конструкция каркаса, предложенная авторами, позволяет значительно расширить диапазон возможных отработок моментов в фермах покрытия, что наглядно доказано с применением математического анализа при исследовании массива цифр, полученных в результате расчетов. Выводы. Результаты исследования позволяют сделать вывод о существенном положительном влиянии предложенного каркаса на распределение моментов в ферме покрытия. Полученные результаты позволяют считать, что разработанная конструкция каркаса усиления расширит область применения типовых ферм покрытия при технологическом перевооружении производственных процессов, а также при реальном восстановлении ферм, поврежденных при техногенном воздействии или боевых действиях, что особо актуально для ряда стран.
Statement of the problem. The problem of comparative analysis by digital technologies of moments in coating farms with a frame and without a reinforcement frame is considered in the study of operation parameters by means of mathematical analysis. Results. As a result of the application of digital technologies, using the finite element method, calculations of moments in coating farms without a frame and with a frame were carried out. The frame design proposed by the authors makes it possible to significantly expand the range of possible developments of moments in the coating farms, which is clearly proved using mathematical analysis in the study of an array of figures obtained as a result of calculations. Conclusions. The results of the study allow us to conclude that the proposed framework has a significant positive effect on the distribution of moments in the coating farm. The results obtained suggest that the developed reinforcement frame design will expand the scope of application of standard coating farms in the technological re-equipment of production processes, as well as in the real restoration of farms damaged by man-made impact or hostilities, which is especially important for a number of countries.
Pelatihan Penggunaan Aplikasi SPSS dan Mendeley Bagi Guru dan Calon Guru Matematika
Authors: Rasikin Widiawati , Chika Rahayu  , Helni Indrayati  
Published: September 2024

Aplikasi SPSS dan Mendeley adalah dua aplikasi yang sangat membantu dalam menyelesaikan suatu karya ilmiah yang berkaitan dengan pengolahan data serta sumber rujukan. Dengan berkembangnya teknologi, kedua aplikasi tersebut sangat diperlukan dan tidak dapat dihindari dalam karya ilmiah khususnya bagi guru dan calon guru matematika. Untuk itu, kegiatan pengabdian ini bertujuan untuk memberikan pemahaman bagi guru dan calon guru matematika dalam menggunakan aplikasi SPSS untuk mengolah data dan aplikasi Mendeley untuk pembuatan daftar pustaka. Pemberian pemahaman tersebut dilakukan dengan cara pemateri memberikan teori dan praktek secara langsung dengan diimbangi peserta yang menggunakan laptop masing-masing yang sudah terinstal aplikasi SPSS dan Mendeley. Subjek pengabdian berasal dari kalangan guru dan calan guru matematika yang berjumlah 70 peserta. Hasil pengabdian menunjukkkan bahwa guru dan calon guru matematika memperoleh pemahaman dalam menggunakan aplikasi SPSS dan Mendeley. Mereka memiliki antusias yang besar dalam mengikuti kegiatan tersebut dan begitu pentingnya memahami penggunaan kedua aplikasi ini. Untuk itu, aplikasi SPSS dan Mendeley menjadi wadah khususnya bagi guru dan calon guru matematika yang sedang menekuni suatu karya ilmiah dan pengolahan data. Perkembangan teknologi telah menuntut adanya pemahaman akan teknologi-teknologi terkini.
Kata kunci: Pelatihan, aplikasi SPSS, aplikasi Mendeley
Brand Personality Selebriti Sebagai Strategi Komunikasi Krisis
Authors: Shabrina Almira , Nugrahani Rah Utami , Nasywa Shafina , Aminia Atala 
Published: September 2024

Pemanfaatan media social TikTok ini menjadikan es teh menjadi salah satu brand minuman yang menjadi top of mind minuman grab and go di Indonesia. Namun, bak pisau bermata dua, penggunaan media sosial menjadi salah satu penyebab permasalahan yang dapat menimbulkan reputasi yang buruk di mata konsumen. Untuk mencegah Citra Perusahaan yang semakin buruk, Es Teh Indonesia melakukan pergantian Chief Executive Officer yang kini dijabat oleh Nagita Slavina. Untuk itu, penelitian ini melihat bagaimana brand personality Nagita Slavina sebagai strategi komunikasi krisis. Penelitian ini menggunakan metode penelitian kualitatif deskriptif untuk melihat bagaimana fenomena pergantian CEO ini menjadi sebuah citra bagi Es Teh Indonesia. Peneliti melakukan penelitian kepada enam informan Generasi Z yang berdomisili di pulau jawa dan mengkonsumsi es teh Indonesia lebih dari 6 kali. Hasil penelitian menunjukan bahwa brand personality Nagita Slavina kurang efektif dalam menangani manajemen krisis yang telah dilakukan oleh Es Teh Indonesia.
Kata Kunci: Brand Personality, Manajemen Krisis, Es Teh Indonesia
Exotic Stable Branches with Efficient TOV Sequences
Authors: Essick Reed 
Published: September 2024

Abstract
Modern inference schemes for the neutron star (NS) equation of state (EoS) require large numbers of stellar models constructed with different EoS, and these stellar models must capture all the behavior of stable stars. I introduce termination conditions for sequences of stellar models for cold nonrotating NSs that can identify all stable stellar configurations up to arbitrarily large central pressures along with an efficient algorithm to build accurate interpolators for macroscopic properties. I explore the behavior of stars with both high- and low-central pressures. Interestingly, I find that EoSs with monotonically increasing sound-speed can produce multiple stable branches (twin stars) and that large phase transitions at high densities can produce stable branches at nearly any mass scale, including sub-solar masses while still supporting stars with M > 2 M
⊙. I conclude with some speculation about the astrophysical implications of this behavior.
Birth of Rapidly Spinning, Overmassive Black Holes in the Early Universe
Authors: Inayoshi Kohei , Ichikawa Kohei 
Published: September 2024

Abstract
The James Webb Space Telescope (JWST) has unveiled numerous massive black holes (BHs) in faint, broad-line active galactic nuclei (AGNs). The discovery highlights the presence of dust-reddened AGN populations, referred to as “little red dots (LRDs),” more abundant than X-ray-selected AGNs, which are less influenced by obscuration. This finding indicates that the cosmic growth rate of BHs within this population does not decrease but rather increases at higher redshifts beyond z ∼ 6. The BH accretion rate density deduced from their luminosity function is remarkably higher than that from other AGN surveys in X-ray and infrared bands. To align the cumulative mass density accreted to BHs with the observed BH mass density at z ≃ 4–5, as derived from the integration of the BH mass function, the radiative efficiency must be doubled from the canonical 10% value, achieving significance beyond the >3σ confidence level. This suggests the presence of rapid spins with 96% of the maximum limit among these BHs under the thin-disk approximation, maintained by prolonged mass accretion instead of chaotic accretion with randomly oriented inflows. Moreover, we derive an upper bound for the stellar mass of galaxies hosting these LRDs, ensuring consistency with galaxy formation in the standard cosmological model, where the host stellar mass is limited by the available baryonic reservoir. Our analysis gives a lower bound for the BH-to-galaxy mass ratio that exceeds the typical value known in the nearby universe and aligns with that for JWST-detected unobscured AGNs. Accordingly, we propose a hypothesis that the dense, dust-rich environments within LRDs facilitate the emergence of rapidly spinning and overmassive BH populations during the epoch of reionization. This scenario predicts a potential association between relativistic jets and other high-energy phenomena with overmassive BHs in the early universe.
Perspectives and attitudes of South African medical professionals towards active euthanasia
Authors: Steyn Willem-Johan , Bondo Mukinay C. 
Published: September 2024

Background: Active euthanasia is a controversial subject both globally and in South Africa. Recent legal cases have kept this topic in the public discourse. Yet, there remains a dearth of quality local research on this issue. This study aimed to explore the views of medical professionals towards active euthanasia to gain a better understanding of this phenomenon in South Africa.Methods: A descriptive-interpretive qualitative research design, using semi-structured in-depth interviews of purposively sampled South African medical professionals, was used to collect the data. The data were analysed using an inductive thematic analysis framework, which included familiarisation, coding, summarising, theme development and thematic review, revision and interpretation.Results: Four general themes, with sub-themes, were identified and inductively analysed: modern medical practice and euthanasia; the problem of suffering in end-of-life care; euthanasia is complex; palliative care in South Africa is poor. Some themes and sub-themes were common to all participants while other themes underscored more diverse views – often because of religious factors.Conclusion: Active euthanasia is a complex and nuanced issue. An understanding of the perceptions and attitudes of medical professionals will contribute to the overall discussion of this phenomenon in ethical, legal, social and political spheres in South Africa. This is of utmost importance given the relevance of this topic in South Africa in the 21st century.Contribution: This study highlights the complex nature of active euthanasia in South Africa among medical professionals while providing a greater understanding of its nuances and the strengths and weaknesses of arguments for or against it.
Serum nutritional predictive biomarkers and risk assessment for anastomotic leakage after laparoscopic surgery in rectal cancer patients
Authors: Shayimu Paerhati , Awula Maitisaidi , Wang Chang-Yong , Jiapaer Rexida , Pan Yi-Peng , Wu Zhi-Min , Chen Yi , Zhao Ze-Liang 
Published: September 2024

BACKGROUND
Anastomotic leakage (AL) is one of the severest complications after laparoscopic surgery for middle/low rectal cancer, significantly impacting patient outcomes. Identifying reliable predictive factors for AL remains a clinical challenge. Serum nutritional biomarkers have been implicated in surgical outcomes but are underexplored as predictive tools for AL in this setting. Our study hypothesizes that preoperative serum levels of prealbumin (PA), albumin (ALB), and transferrin (TRF), along with surgical factors, can accurately predict AL risk.
AIM
To determine the predictive value of preoperative serum nutritional biomarkers for rectal cancer AL following laparoscopic surgery.
METHODS
In the retrospective cohort study carried out at a tertiary cancer center, we examined 560 individuals who underwent laparoscopic procedures for rectal cancer from 2018 to 2022. Preoperative serum levels of PA, ALB, and TRF were measured. We employed multivariate logistic regression to determine the independent risk factors for AL, and a predictive model was constructed and evaluated using receiver operating characteristic curve analysis.
RESULTS
AL occurred in 11.96% of cases, affecting 67 out of 560 patients. Multivariate analysis identified PA, ALB, and TRF as the independent risk factor, each with an odds ratio of 2.621 [95% confidence interval (CI): 1.582-3.812, P = 0.012], 3.982 (95%CI: 1.927-4.887, P = 0.024), and 2.109 (95%CI: 1.162-2.981, P = 0.031), respectively. Tumor location (< 7 cm from anal verge) and intraoperative bleeding ≥ 300 mL also increased AL risk. The predictive model demonstrated an excellent accuracy, achieving an area under the receiver operating characteristic curve of 0.942, a sensitivity of 0.844, and a specificity of 0.922, demonstrating an excellent ability to discriminate.
CONCLUSION
Preoperative serum nutritional biomarkers, combined with surgical factors, reliably predict anastomotic leakage risk after rectal cancer surgery, highlighting their importance in preoperative assessment.
Adjuvant chemotherapy for isolated resectable colorectal lung metastasis: A retrospective study using inverse probability treatment weighting propensity analysis
Authors: Gao Zhao , Wu Shi-Kai , Zhang Shi-Jie , Wang Xin , Wu Ying-Chao , Jin Xuan 
Published: September 2024

BACKGROUND
The benefit of adjuvant chemotherapy (ACT) for patients with no evidence of disease after pulmonary metastasis resection (PM) from colorectal cancer (CRC) remains controversial.
AIM
To assess the efficacy of ACT in patients after PM resection for CRC.
METHODS
This study included 96 patients who underwent pulmonary metastasectomy for CRC at a single institution between April 2008 and July 2023. The primary endpoint was overall survival (OS); secondary endpoints included cancer-specific survival (CSS) and disease-free survival (DFS). An inverse probability of treatment-weighting (IPTW) analysis was conducted to address indication bias. Survival outcomes compared using Kaplan-Meier curves, log-rank test, Cox regression and confirmed by propensity score-matching (PSM).
RESULTS
With a median follow-up of 27.5 months (range, 18.3-50.4 months), the 5-year OS, CSS and DFS were 72.0%, 74.4% and 51.3%, respectively. ACT had no significant effect on OS after PM resection from CRC [original cohort: P = 0.8; IPTW: P = 0.17]. No differences were observed for CSS (P = 0.12) and DFS (P = 0.68) between the ACT and non-ACT groups. Multivariate analysis showed no association of ACT with better survival, while sublobar resection (HR = 0.45; 95%CI: 0.20-1.00, P = 0.049) and longer disease-free interval (HR = 0.45; 95%CI: 0.20-0.98, P = 0.044) were associated with improved survival.
CONCLUSION
ACT does not improve survival after PM resection for CRC. Further well-designed randomized controlled trials are needed to determine the optimal ACT regimen and duration.
Effects of postoperative treatment with chemotherapy and cellular immunotherapy on patients with colorectal cancer
Authors: Ding Zhen-Yu , Piao Ying , Jiang Tong , Chen Juan , Wang Yi-Nuo , Yu Hui-Ying , Zheng Zhen-Dong 
Published: September 2024

BACKGROUND
The outcome of surgical treatment for colorectal cancer (CRC) remains unsatisfactory and warrants further exploration and optimization.
AIM
To clarify the impact of chemotherapy plus cellular immunotherapy [dendritic cell-cytokine-induced killer (DC-CIK) cell immunotherapy] on patients after CRC surgery and to explore the mediating variables.
METHODS
A total cohort of 121 patients who underwent CRC surgery between July 2020 and October 2023 were selected. The sample comprised a control group of 55 patients who received the XELOX chemotherapy regimen and a research group of 66 patients who received XELOX + DC-CIK immunotherapy. We performed comparative analyses of the clinical and pathological data of the two groups, including efficacy, the incidence of adverse events (diarrhea, myelosuppression, gastrointestinal reactions, and peripheral neuritis), serum levels of tumor markers [carcinoembryonic antigens and carbohydrate antigens (CA)19-9 and CA242], and T-cell subsets [cluster of differentiation (CD)3+, CD3+ CD4+, CD3+ CD8+, natural killer (NK), and NK T cells]. We also conducted preliminary univariate and multivariate analyses of the variables that affected the efficacy of the treatments.
RESULTS
We found a significantly higher rate of treatment efficacy in the research group than in the control group, with a statistically lower incidence of adverse events. Both groups showed a reduction in serum tumor markers after treatment but there was no marked intergroup difference. After treatment, the various T-cell subgroup indicators in the control group were significantly lower than those in the research group. The indices of T-cell subsets in the research group showed no significant change from preoperative levels. Univariate analysis revealed a significant correlation between TNM staging, tumor differentiation, and the rates of nonresponse to treatment in CRC patients after surgery. Multivariate results indicated that the treatment approach significantly affected the efficacy of postoperative CRC treatment.
CONCLUSION
We concluded that XELOX + DC-CIK immunotherapy for postsurgical CRC patients offers reduced rates of treatment-induced adverse events, improved curative effects, enhanced immunity, and increased physiological antitumor responses.
Comparison of efficacy and safety of nab-paclitaxel and oxaliplatin + S-1 and standard S-1 and oxaliplatin chemotherapy regimens for treatment of gastric cancer
Authors: Wang Yi-Cong , Feng Long , Wang Gong-Ping , Yu Peng-Jie , Guo Can , Cai Bao-Jia , Song Yan , Pan Ting , Lin Bo-Hao , Li Yuan-Dong , Xiao Jing-Jing 
Published: September 2024

BACKGROUND
Gastric cancer (GC) is a relatively frequent clinical phenomenon, referring to malignant tumors emerging in the gastric mucosal epithelial cells. It has a high morbidity and mortality rate, posing a significant threat to the health of patients. Hence, how to diagnose and treat GC has become a heated topic in this research field.
AIM
To discuss the effectiveness and safety of nab-paclitaxel in combination with oxaliplatin and S-1 (P-SOX) for the treatment of GC, and to analyze the factors that may influence its outcomes.
METHODS
A total of 219 eligible patients with advanced GC, who were treated at Qinghai University Affiliated Hospital Gastrointestinal Oncology between January 2018 and March 2020, were included in the study. Among them, 149 patients received SOX regimen and 70 patients received S-1 regimen. All patients underwent both preoperative and postoperative chemotherapy consisting of 2-4 cycles each, totaling 6-8 cycles, along with parallel D2 radical surgical treatment. The patients were followed up for a period of three years or until reaching the event endpoint.
RESULTS
The short-term and long-term efficacy of the P-SOX group was significantly higher than that of the SOX group, and the safety was manageable. Cox multivariate analysis revealed that progression-free survival was associated with perioperative chemotherapy efficacy, tumor diameter ≤ 2cm, high differentiation, and early cTNM (T stands for invasion depth; N stands for node metastasis; M stands for distant invasion) stage.
CONCLUSION
In comparison to the SOX regimen, the P-SOX regimen demonstrates improved short-term and long-term efficacy with tolerable adverse reactions. It is anticipated that the P-SOX regimen will emerge as a first-line chemotherapy option for GC. Patients with GC who receive effective perioperative chemotherapy (Response Evaluation Criteria in Solid Tumors 1.1, Tumor Regression Grade), have a tumor diameter ≤ 2cm, exhibit high degree of differentiation, and are at an early cTNM stage show better prognosis.
Relationship between intracranial pressure and neurocognitive function among older adults after radical resection of rectal cancer
Authors: Song Bo , Li Li-Ping , Wang Xiao-Lin , Guo Yong , Li Jun 
Published: September 2024

BACKGROUND
Older patients are prone to postoperative cognitive decline after laparoscopic rectal cancer surgery, which may be associated with increased intraoperative intracranial pressure (ICP). This study investigated the correlation between intraoperative ICP changes, as indicated by measurements of the optic nerve sheath diameter (ONSD) using ultrasonography, and subsequent cognitive function to provide better patient care.
AIM
To evaluate changes in ICP and associated postoperative neurocognition in older adults after laparoscopic radical resection for rectal cancer.
METHODS
We included 140 patients who visited the Mianyang Central Hospital for malignant rectal tumors, measured their ONSDs before surgery and 30 and 60 minutes after the Trendelenburg position during surgery, and evaluated the patients’ cognitive function 1 day before surgery and 1, 4, and 7 days after surgery. The Mini-Mental State Examination (MMSE) and confusion assessment method (CAM) scores of the patients with different ONSDs were compared at different times after surgery.
RESULTS
In patients with an ONSD greater than 5.00 mm (group A1), the MMSE scores at 1 day and 4 days after surgery were significantly lower than those of patients with an ONSD less than or equal to 4.00 mm (group A2) (P < 0.05). The CAM scores of group A1 were significantly higher than those of group A2 (P < 0.05). The MMSE scores of group A1 on days 1 and 4 after surgery were significantly lower than those 1 day before and 7 days after surgery (P < 0.05), while the CAM scores 1 day and 4 days after surgery were significantly higher than those 1 day before and 7 days after surgery.
CONCLUSION
Decline in cognitive function among older adults after the procedure may be related to intracranial hypertension during surgery.
Prevention and management of postoperative deep vein thrombosis in lower extremities of patients with gastrointestinal tumor
Authors: Shu Liang , Xia Cheng-Wei , Pang Yu-Fan 
Published: September 2024

BACKGROUND
Deep vein thrombosis (DVT) is a significant postoperative concern, particularly in patients undergoing surgery for gastrointestinal (GI) cancers. These patients often present multiple risk factors, including advanced age and elevated body mass index (BMI), which can increase the likelihood of thromboembolic events. Effective prophylaxis is crucial in this high-risk population to minimize complications such as DVT and pulmonary embolism (PE). This study investigates a comprehensive DVT prevention protocol, combining mechanical and pharmacological strategies alongside early mobilization, to evaluate its effectiveness and safety in reducing postoperative thrombosis rates among GI cancer surgery patients.
AIM
To evaluate the effectiveness and safety of postoperative DVT prevention strategies in patients with GI cancer.
METHODS
A prospective cohort study was conducted involving 100 patients who underwent surgery for GI tumors between January and December 2022. All patients received a standardized DVT prevention protocol, which included risk assessment, mechanical prophylaxis, pharmacological prophylaxis, and early mobilization. The primary endpoint was the incidence of DVT within 30 days postoperatively. Secondary outcomes included the occurrence of PE, bleeding complications, and adherence to the protocol.
RESULTS
The overall incidence of DVT was 7% (7/100 patients). One patient (1%) developed PE. The adherence rate to the prevention protocol was 92%. Bleeding complications were observed in 3% of patients. Significant risk factors for DVT development included advanced age [odds ratio (OR): 1.05; 95% confidence interval (95%CI): 1.01-1.09], higher BMI (OR: 1.11; 95%CI: 1.03-1.19), and longer operative time (OR: 1.007; 95%CI: 1.001-1.013).
CONCLUSION
Implementing a comprehensive DVT prevention and management protocol for patients undergoing GI tumor surgery resulted in a lower incidence. Strict adherence and individualized risk assessment are crucial for optimizing outcomes.