bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coping Strategies of Economically (Partially) Inactive Households: The Case of Croatia
Authors: Bagić Dragan , Dobrotić Ivana , Lažnjak Jasminka , Rodik Petra , Vučkovićjuroš Tanja 
Published: October 2017

Abstract
How do households with inactive or unemployed members face growing risks and uncertainty? The present study tackles this problem with a case study on Croatia, a country at the bottom of the European Union’s (EU) scale of economic activity rate. The low level of activity that has characterized Croatia for more than twenty years has been accompanied by a continuously high unemployment rate, which has further increased since 2009. In this context, households with (long-term) inactive or unemployed members have had to develop alternative coping strategies. In order to identify and examine these strategies, in 2014 we conducted a mixed-method study, including a quantitative survey of 453 households and 37 semi-structured interviews. We identified six household strategies, more or less ‘successful’ in terms of the household’s material position. In this essay we further examine these strategies’ characteristics and implications, with a focus on the profiles of households employing specific strategies.
Scholars (Not) Investigating Srebrenica. Academic Feuds and Other Shortcomings
Authors: Duijzings Ger 
Published: October 2017

Abstract
Fifteen years after the publication of the Srebrenica report by the Netherlands Institute for War Documentation (NIOD), the Srebrenica genocide has not become subject of more scholarly and historical research. On the contrary, academics prefer to keep their hands off the topic, confining themselves to ‘theoretical’, ‘reflexive’, or ‘moralistic’ reflections on the work done by the NIOD team. Symptomatic of the current state of inertia and diminishing professional standards is the recent book by the Dutch historian and psychologist Eelco Runia in which he attacks the NIOD report from a psychoanalytic standpoint.
Wattwaage mit Hebelübersetzung auf Basis eines kommerziellen EMK-Wägesystems
Authors: Hilbrunner Falko , Rahneberg Ilko , Fröhlich Thomas 
Published: October 2017

Zusammenfassung
Bei Waagen nach dem Prinzip der elektromagnetischen Kraftkompensation
wird die auf eine Waagschale wirkende Gewichtskraft eines Wägegutes
durch eine elektromagnetische Gegenkraft kompensiert. Nach dem Stand
der Technik wird der Zusammenhang zwischen dem, die Gegenkraft
erzeugendem Aktorstrom durch eine Spule und der Gewichtskraft des
Wägegutes durch Kalibrierung mit Massenormalen hergestellt. Mit der
für 2018 zu erwartenden Neudefinition der SI-Einheit der Masse durch
Festlegung eines Wertes der Planck-Konstanten wird ein unmittelbarer
Zusammenhang zwischen den mechanischen und elektrischen Größen
geschaffen, so dass das aus Fundamentalexperimenten bekannte
Wattwaagenprinzip zur Kalibrierung von Massen eingesetzt werden kann.
Im vorliegenden Artikel wird eine darauf aufbauende Methode zur
Bestimmung des Kraftfaktors Bl einer kommerziellen EMK-Wägzelle
vorgestellt. Dies geschieht durch die simultane Messung der Spannung
über der im Magnetfeld bewegten Spule und deren Geschwindigkeit.
Dabei wird im vorgestellten Verfahren die Spule gleichzeitig zur
Erzeugung der Bewegung mit einem harmonischen Wechselsignal bestromt.
Die Frequenz der harmonischen Bewegung hat hierbei maßgeblichen
Einfluss auf die Unsicherheit des resultierenden Kraftfaktors. Eine
Trennung der Spannungsanteile über der Spule erfolgt durch simultane
Messung von Strom und Spannung an der Spule und Auswertung unter
Berücksichtigung der vorliegenden Amplituden und Phasenlagen. Die
Spule ist hierbei, wie bei kommerziellen EMK-Wägezellen üblich, über
ein mechanisches Hebelwerk angekoppelt. Durch diese Hebelübersetzung
ist es möglich, mit einem kompakten elektrodynamischen Aktuator
(Spule–Permanentmagnetsystem), einen großen wirksamen Kraftfaktor zu
realisieren.
Im Ergebnis können mit dem System Kräfte in beliebiger Raumrichtung
gemessen bzw. erzeugt werden, wobei die Massebestimmung einen
Spezialfall darstellt, für den zusätzlich die lokale
Fallbeschleunigung bekannt sein muss. Unter Nutzung der gleichen
Methodik kann durch Vertauschung von Eingangs- und Ausgangsgrößen des
Formalismus, die EMK-Wägezelle auch als Positionssensor eingesetzt
werden. Hierbei erfolgt unter Zuhilfenahme eines Referenzgewichtes
(Justiergewichtes) und der Ausgangsspannung des Positionssensors des
Wägesystems eine Kalibrierung der Auslenkung des Koppelstücks. Für
beide Verfahren werden im Gegensatz zu Fundamentalexperimenten
industriell relevante Messunsicherheiten im ppm-Bereich
angestrebt. Es werden Messungen für beide Messmodi auf Basis
kommerziell verfügbarer EMK-Wägezellen und elektrischer Messtechnik
vorgestellt und diskutiert.
Bestimmung der temperaturabhängigen Oberflächenspannung des Eisen-Nickel-Systems mittels elektromagnetischer Levitation
Authors: Leitner Thomas , Klemmer Olivia , Pottlacher Gernot 
Published: October 2017

Zusammenfassung
Für das Eisen-Nickel-Legierungssystem wird die Oberflächenspannung in Abhängigkeit der Temperatur in der flüssigen Phase
untersucht. Hierfür kommt an der Technischen Universität Graz (TU Graz) die Methode des oszillierenden Tropfens (engl.:
oscillating drop, OD) in Kombination mit einer elektromagnetischen Levitations-Apparatur zum Einsatz.
Die elektromagnetische Levitation (EML) stellt eine elegante experimentelle Methode dar, um die Oberflächenspannung und
Dichte von Reinmetallen und Legierungen zu untersuchen, da sie den Anforderungen einer kontaktfreien, behältnislosen
Messmethode genügt. Mittels Hochgeschwindigkeitskameras und Software zur Kantenerkennung wird das Volumen sowie ein
Frequenzspektrum der Oberflächenoszillationen der Probe ermittelt. Aus den Oszillationsfrequenzen kann schließlich die
Oberflächenspannung berechnet werden.
Essentiell für dieses Experiment ist die Temperaturmessung, die ebenfalls kontaktlos mittels Einwellenlängen-Pyrometer
durchgeführt wird, wobei eine Kalibration des Emissionsgrades bei einer Referenztemperatur, z. B. am Schmelz- oder
Erstarrungsplateau erfolgt. Zusätzlich wird seit kurzem ein Zweiwellenlängen-Pyrometer im Quotientenmodus genutzt, um die
Resultate der Temperaturmessung zu überprüfen.
Diese Arbeit enthält aktuelle experimentelle Messergebnisse mit einer Unsicherheitsangabe nach GUM. Die ermittelten
Messdaten werden, sofern verfügbar, mit bereits existierenden experimentellen Daten aus der Literatur verglichen.
Experimental and Analytical Modal Analysis of Cantilever Beam for Vibration Based Damage Identification Using Artificial Neural Network
Authors: Rao P. S. , Ramakrishna V. , Mahendra N. V. D. 
Published: October 2017

AbstractThis paper presented procedures of experimental and analytical modal analysis of cantilever beam used for vibration-based damage identification using an artificial neural network (ANN). It is a part of structural health monitoring. The process of implementing a damage detection strategy for aerospace, civil, and mechanical engineering structures is referred to as SHM. Experimental modal analysis involves acquisition of point-to-point frequency response functions at a set of points for a dynamic model. Analytical modal analysis uses differential equations of motion of a structure using a theoretical and finite element modeling technique. In experimental modal analysis, the transient excitation method of modal testing is conducted using an impact hammer test. We considered two cantilever beams of different materials, i.e., aluminum and stainless steel. Different crack lengths were introduced on the beams by cutting the slot. Slot lengths were 2, 4, 6, 8, and 10 mm, with cracks designated as damage level 1, 2, 3, 4, and 5, respectively. The undamaged cantilever structure was treated as damage level 0. The analytical modal analysis was performed using ANSYS 15. The geometric models for analytical modal analysis were developed using CATIA V5R20. A cantilever beam of longitudinal crack at different crack lengths and materials was considered for analysis. The experimental modal analysis was validated with analytical modal analysis. It was observed that there was no change in the first mode; for higher modes, there is a decrease in natural frequencies with the increase in crack length. Frequency response functions were obtained from the experimental modal analysis. These can be used for damage identification using ANN.
Dmrt5, a Novel Neurogenic Factor, Reciprocally Regulates Lhx2 to Control the Neuron–Glia Cell-Fate Switch in the Developing Hippocampus
Authors: Muralidharan Bhavana , Keruzore Marc , Pradhan Saurabh J. , Roy Basabdatta , Shetty Ashwin S. , Kinare Veena , D'Souza Leora , Maheshwari Upasana , Karmodiya Krishanpal , Suresh Agasthya , Galande Sanjeev , Bellefroid Eric J. , Tole Shubha 
Published: October 2017

Regulation of the neuron–glia cell-fate switch is a critical step in the development of the CNS. Previously, we demonstrated that Lhx2 is a necessary and sufficient regulator of this process in the mouse hippocampal primordium, such that Lhx2 overexpression promotes neurogenesis and suppresses gliogenesis, whereas loss of Lhx2 has the opposite effect. We tested a series of transcription factors for their ability to mimic Lhx2 overexpression and suppress baseline gliogenesis, and also to compensate for loss of Lhx2 and suppress the resulting enhanced level of gliogenesis in the hippocampus. Here, we demonstrate a novel function of Dmrt5/Dmrta2 as a neurogenic factor in the developing hippocampus. We show that Dmrt5, as well as known neurogenic factors Neurog2 and Pax6, can each not only mimicLhx2overexpression, but also can compensate for loss of Lhx2 to different extents. We further uncover a reciprocal regulatory relationship between Dmrt5 and Lhx2, such that each can compensate for loss of the other. Dmrt5 and Lhx2 also have opposing regulatory control onPax6andNeurog2, indicating a complex bidirectionally regulated network that controls the neuron–glia cell-fate switch.SIGNIFICANCE STATEMENTWe identify Dmrt5 as a novel regulator of the neuron–glia cell-fate switch in the developing hippocampus. We demonstrate Dmrt5 to be neurogenic, and reciprocally regulated by Lhx2: loss of either factor promotes gliogenesis; overexpression of either factor suppresses gliogenesis and promotes neurogenesis; each can substitute for loss of the other. Furthermore, each factor has opposing effects on established neurogenic genesNeurog2andPax6. Dmrt5 is known to suppress their expression, and we show that Lhx2 is required to maintain it. Our study reveals a complex regulatory network with bidirectional control of a fundamental feature of CNS development, the control of the production of neurons versus astroglia in the developing hippocampus.Finally, we confirm that Lhx2 binds a highly conserved putative enhancer ofDmrt5, suggesting an evolutionarily conserved regulatory relationship between these factors. Our findings uncover a complex network that involves Lhx2, Dmrt5, Neurog2, and Pax6, and that ensures the appropriate amount and timing of neurogenesis and gliogenesis in the developing hippocampus.
Persistent hyperthyroidism and de novo Graves’ ophthalmopathy after total thyroidectomy
Authors: Tay Wei Lin , Loh Wann Jia , Lee Lianne Ai Ling , Chng Chiaw Ling 
Published: October 2017

Summary
We report a patient with Graves’ disease who remained persistently hyperthyroid after a total thyroidectomy and also developed de novo Graves’ ophthalmopathy 5 months after surgery. She was subsequently found to have a mature cystic teratoma containing struma ovarii after undergoing a total hysterectomy and salpingo-oophorectomy for an incidental ovarian lesion.

Learning points:

It is important to investigate for other causes of primary hyperthyroidism when thyrotoxicosis persists after total thyroidectomy.

TSH receptor antibody may persist after total thyroidectomy and may potentially contribute to the development of de novo Graves’ ophthalmopathy.
Dendritic Cytoskeletal Architecture Is Modulated by Combinatorial Transcriptional Regulation in Drosophila melanogaster
Authors: Das Ravi , Bhattacharjee Shatabdi , Patel Atit A , Harris Jenna M , Bhattacharya Surajit , Letcher Jamin M , Clark Sarah G , Nanda Sumit , Iyer Eswar Prasad R , Ascoli Giorgio A , Cox Daniel N 
Published: October 2017

Abstract
Transcription factors (TFs) have emerged as essential cell autonomous mediators of subtype specific dendritogenesis; however, the downstream effectors of these TFs remain largely unknown, as are the cellular events that TFs control to direct morphological change. As dendritic morphology is largely dictated by the organization of the actin and microtubule (MT) cytoskeletons, elucidating TF-mediated cytoskeletal regulatory programs is key to understanding molecular control of diverse dendritic morphologies. Previous studies in Drosophila melanogaster have demonstrated that the conserved TFs Cut and Knot exert combinatorial control over aspects of dendritic cytoskeleton development, promoting actin and MT-based arbor morphology, respectively. To investigate transcriptional targets of Cut and/or Knot regulation, we conducted systematic neurogenomic studies, coupled with in vivo genetic screens utilizing multi-fluor cytoskeletal and membrane marker reporters. These analyses identified a host of putative Cut and/or Knot effector molecules, and a subset of these putative TF targets converge on modulating dendritic cytoskeletal architecture, which are grouped into three major phenotypic categories, based upon neuromorphometric analyses: complexity enhancer, complexity shifter, and complexity suppressor. Complexity enhancer genes normally function to promote higher order dendritic growth and branching with variable effects on MT stabilization and F-actin organization, whereas complexity shifter and complexity suppressor genes normally function in regulating proximal-distal branching distribution or in restricting higher order branching complexity, respectively, with spatially restricted impacts on the dendritic cytoskeleton. Collectively, we implicate novel genes and cellular programs by which TFs distinctly and combinatorially govern dendritogenesis via cytoskeletal modulation.
Toward a qualitative understanding of binge-watching behaviors: A focus group approach
Authors: Flayelle Maèva , Maurage Pierre , Billieux Joël 
Published: October 2017

Background and aims
Binge-watching (i.e., seeing multiple episodes of the same TV series in a row) now constitutes a widespread phenomenon. However, little is known about the psychological factors underlying this behavior, as reflected by the paucity of available studies, most merely focusing on its potential harmfulness by applying the classic criteria used for other addictive disorders without exploring the uniqueness of binge-watching. This study thus aimed to take the opposite approach as a first step toward a genuine understanding of binge-watching behaviors through a qualitative analysis of the phenomenological characteristics of TV series watching.

Methods
A focus group of regular TV series viewers (N = 7) was established to explore a wide range of aspects related to TV series watching (e.g., motives, viewing practices, and related behaviors).

Results
A content analysis identified binge-watching features across three dimensions: TV series watching motivations, TV series watching engagement, and structural characteristics of TV shows. Most participants acknowledged that TV series watching can become addictive, but they all agreed having trouble recognizing themselves as truly being an “addict.” Although obvious connections could be established with substance addiction criteria and symptoms, such parallelism appeared to be insufficient, as several distinctive facets emerged (e.g., positive view, transient overinvolvement, context dependency, and low everyday life impact).

Discussion and conclusion
The research should go beyond the classic biomedical and psychological models of addictive behaviors to account for binge-watching in order to explore its specificities and generate the first steps toward an adequate theoretical rationale for these emerging problematic behaviors.
Relabáló/refrakter Hodgkin-lymphoma brentuximab vedotin kezelése. Hazai tapasztalatok
Authors: Molnár Zsuzsa , Pinczés László Imre , Piukovics Klára , Istenes Ildikó , Wolf Krisztina , Csukly Zoltán , Szomor Árpád , Illés Árpád , Miltényi Zsófia 
Published: October 2017

Abstract: Introduction: The treatment of relapsed or refractory Hodgkin lymphoma is still a major therapeutic challenge. The use of brentuximab vedotin, an anti-CD30 antibody-drug conjugate, represents a promising approach for these patients, however clinical outcomes have not yet been evaluated in Hungary. Aim: Our aim was to assess the efficacy, safety and outcome of brentuximab vedotin treatment in Hungarian Hodgkin lymphoma patients. Method: In this retrospective case note review we enrolled patients at 6 clinical sites countrywide who were diagnosed with Hodgkin lymphoma and received brentuximab vedotin between 1 January 2013 and 31 December 2016. Results: A total of 86 patients were treated with brentuximab vedotin during the examined period. Before therapy initiation 66% of our patients had advanced-stage disease. Overall response rate to brentuximab vedotin, administered before autologous hematopoietic stem cell transplantation (n = 54) was 66.6%, complete remission rate was 42.6%. Thirty patients received brentuximab vedotin after AHSCT, 46.67% responded to treatment, 30% achieved complete remission. Thirty-six patients received the drug as a single-agent therapy, 50 patients were given brentuximab vedotin in combination, 39 of them with bendamustin. Toxicity was observed only in 13.95% of our patients, most common symptom was skin rash. Based on our analysis the estimated 5-year overall survival rate was 78.7%, the estimated progression free survival rate was 23.59 months (95% CI: 19.50–27.68). Conclusion: Brentuximab vedotin carries a substantial improvement in the treatment of relapsed or refractory Hodgkin lymphoma. Our results underline prior observations published in the literature. The use of brentuximab vedotin in combination can be beneficial, however further investigation is needed on the subject. Orv Hetil. 2017; 158(41): 1630–1634.
A Waldenström-macroglobulinaemia és betegségre szabott kezelése
Authors: Szemlaky Zsuzsanna , Mikala Gábor 
Published: October 2017

Abstract: Waldenström’s macroglobulinaemia is a form of lymphoplasmocytic lymphoma that preferentially localizes to the bone marrow and causes a special syndrome characterized by monoclonal IgM hypersecretion. Recent results point to the fact that this disease has at least three different pathobiological forms with different clinical presentation. While mutations of MYD88 occur in 95–97% of the cases, there are CXCR4 mutations in 30–40%, ARID1A mutations in 17% and CD79B mutations in approximately 10% of afflicted individuals. CXCR pathway signaling is able to transcriptionally silence tumor suppressors induced by MYD88 activation. Patients with mutated MYD88 and CXCR4 present with higher tumor burden, slower developing and less deep response upon therapy with more frequent resistance. In this review, based on the most recent data, a treatment selection advice is provided for the therapy of symptomatic patients. Orv Hetil. 2017; 158(41): 1604–1614.
Las representaciones sociales: una forma de investigar la realidad educativa
Authors: Fernández Sierra Myriam , Hernández Pichardo Análida 
Published: October 2017

El presente artículo plantea un acercamiento a la concepción de representación social con el propósito de identificar elementos para su abordaje, partiendo de us génesis e identificando algunos de los representantes que desde la psicología social y la sociología han aportado consideraciones valiosas que transforman el estudio de las representaciones sociales en un ámbito de amplias posibilidades en la investigación educativa. Se espera abrir un debate sobre la construcción de las representaciones sociales como espacio de búsqueda de sentido en lo educativo, aportando elementos de los hallazgos investigativos de las autoras sobre las representaciones sociales de los adolescentes en el ámbito educativo.
CARING FOR “PARENTLESS” CHILDREN: AN EXPLORATION OF WORK STRESSORS AND RESOURCES AS EXPERIENCED BY CAREGIVERS IN CHILDREN’S HOMES IN GHANA
Authors: Darkwah Ernest , Asumeng Maxwell , Daniel Marguerite 
Published: October 2017

The experience of stress by workers in any work environment has negative impacts on employee health and productivity. However, work resources are known to have possible neutralizing impacts on the negative effects of stress depending on the availability of those resources and the extent to which employees are able to identify and utilize them. This study explores this stress–resource relationship and its implications in a work context where the lives of vulnerable children depend on the wellbeing and productivity of their employed caregivers. Qualitative exploratory techniques were used to investigate the sources and nature of stressors experienced by caregivers and the extent to which caregivers identify and utilize resources available in that work environment. Participants comprised 41 caregivers from 2 children’s homes in Ghana. It emerged that aspects of the work environment that were identified as stressors also tended to be identified as resources for caregivers. These included the children, the work environment, institution–community relations, and relationships between caregivers and their own families. Caregiver faith and intrinsic motivation stood out as the most frequently reported of the resources upon which caregivers drew to cope with their jobs.