bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vaping causes an acute BMI‐dependent change in pulmonary blood flow
Authors: Burrowes K. S. , Seal M. , Noorababaee L. , Pontré B. , Dubowitz D. , Sá R. C. , Prisk G. K. 
Published: October 2024

AbstractVaping use has skyrocketed especially among young adults, however there is no consensus on how vaping impacts the lungs. We aimed to determine whether there were changes in lung function acutely after a standard vaping session or if there were differences in lung function metrics between a healthy never‐vaping cohort (N = 6; 27.3 ± 3.0 years) and a young asymptomatic vaping cohort (N = 14; 26.4 ± 8.0 years) indicating chronic changes. Pulmonary function measurements and impulse oscillometry were obtained on all participants. Oxygen‐enhanced and Arterial Spin Labelling MRI were used to measure specific ventilation and perfusion, respectively, before and after vaping, and in the control cohort at baseline. MRI metrics did not show any significant differences in specific ventilation or perfusion after vaping. Heart rate increased post‐vaping (68.1 ± 10.5 to 71.3 ± 8.7, p = 0.020); however, this and other metrics did not show a nicotine dose‐dependent effect. There was a significant negative correlation between BMI and change in mean perfusion post‐vaping (p = 0.003); those with normal/low BMI showing an increase in perfusion and vice versa for high BMI. This may be due to subjects lying supine during vaping inhalation. Pulmonary function metrics indicative of airways resistance showed significant differences between the vaping and control cohorts indicating early airway changes.
Neonatal reference intervals for serum steroid hormone concentrations measured by LC-MS/MS
Authors: Olthof Anouk , Naafs Jolanda C. , Zwaveling-Soonawala Nitash , Heinen Charlotte A. , Hannema Sabine E. , Hillebrand Jacquelien J. , Boelen Anita , van Trotsenburg Paul A.S. , Heijboer Annemieke C. 
Published: October 2024

Abstract

Objectives
Congenital adrenal hyperplasia (CAH) is a rare, inherited disorder of adrenal steroid synthesis. In many countries it is part of the neonatal screening program enabling early diagnosis and treatment. In case of an abnormal neonatal screening result or when other differences of sexual development (DSD) are suspected, measurement of serum steroid hormones using liquid chromatography coupled to mass spectrometry (LC-MS/MS) is needed for further diagnosis. However, reliable age- and sex-specific reference intervals (RIs) for serum steroid hormones during the neonatal period are missing. We therefore aimed to establish LC-MS/MS based RIs for serum steroid hormones in neonates.

Methods
Serum was obtained from healthy term neonates at two time points: 130 samples at day 3–8 (T1, time of the neonatal screening) and 126 samples at day 13–15 (T2, two weeks old). Concentrations of cortisol, cortisone, corticosterone, 11-deoxycortisol, 21-deoxycortisol, 11-deoxycorticosterone, testosterone, androstenedione, and 17-hydroxyprogesterone (17-OHP) were measured using LC-MS/MS.

Results
RIs (in nmol/L) were established for T1 and T2: cortisone (19.3–215;18.0–212), cortisol (10.0–407;8.4–446), corticosterone (<31;<50), 11-deoxycortisol (0.73–4.6;0.70–3.6), 17-OHP (<4.9;<5.1), androstenedione (0.3–1.8;0.3–2.7), 11-deoxycorticosterone (<0.2;<0.2), and 21-deoxycortisol (<1;<1), respectively. Testosterone differed between boys and girls: RIs at T1 and T2 for boys were 0.27–4.3 and 0.63–13.9, and for girls<0.30 and <0.47, respectively.

Conclusions
We established LC-MS/MS based RIs for cortisol, cortisone, corticosterone, 11-deoxycortisol, 21-deoxycortisol, 11-deoxycorticosterone, testosterone, androstenedione, and 17-OHP in neonates in the first and second week of life.
Nonlinear poro thermal vibration and parametric excitation in a magneto-elastic embedded nanobeam using homotopy perturbation technique
Authors: Anitha Lakshmanan , Vadivukarasi Loganathan , Selvamani Rajendran , Dimitri Rossana , Tornabene Francesco 
Published: October 2024

Abstract
The primary focus of this study is to analyze the nonlinear vibration patterns and parametric excitation of embedded Euler–Bernoulli nanobeams subjected to thermo-magneto-mechanical loads. The Euler–Bernoulli nanobeam is developed with external parametric excitation. By utilizing nonlocal continuum theory and nonlinear von Karman beam theory, the governing equation of motion is derived. Subsequently, the homotopy perturbation technique is employed to determine the vibration frequencies. Finally, the modulation equation of Euler–Bernoulli nanobeams is derived for simply supported boundary conditions. The impacts of magnetic potential, temperature, damping coefficient, Winkler coefficient, and nonlocal parameters are tested numerically on nonlinear frequency–amplitude and parametric excitation–amplitude responses. Results demonstrate that physical variables significantly influence both nonlinear frequency behavior and parametric excitation.
On bivariate fractal interpolation for countable data and associated nonlinear fractal operator
Authors: Pandey Kshitij Kumar , Secelean Nicolae Adrian , Viswanathan Puthan Veedu 
Published: October 2024

Abstract
Fractal interpolation has been conventionally treated as a method to construct a univariate continuous function interpolating a given finite data set with the distinguishing property that the graph of the interpolating function is the attractor of a suitable iterated function system. On the one hand, attempts have been made to extend the univariate fractal interpolation from a finite data set to a countably infinite set. On the other hand, fractal interpolation in higher dimensions, particularly the theory of fractal interpolation surfaces (FISs), has received increasing attention for more than a quarter century. This article targets a two-fold extension of the notion of fractal interpolation by providing a general framework to construct FISs for a prescribed set consisting of countably infinite data on a rectangular grid. By using this as a crucial tool, we obtain a parameterized family of bivariate fractal functions simultaneously interpolating and approximating a prescribed bivariate continuous function. Some elementary properties of the associated nonlinear (not necessarily linear) fractal operators are established, thereby allowing the interaction of the notion of fractal interpolation with the theory of nonlinear operators.
A novel miniaturized microstrip filtering power divider with high selectivity based on composite right/left-handed (CRLH) concept
Authors: Danaeian Mostafa 
Published: October 2024

Abstract
This paper proposes a compact microstrip filtering power divider (FPD) with high selectivity and equal power division ratios based on the composite right/left-handed (CRLH) concept. The proposed equal microstrip FPD is designed by cascading two CRLH unit cells and a grounded via hole. The proposed CRLH unit cell is realized by an interdigital capacitor loaded between two transmission lines (TL) on the upper metal layer and the fractal/meander complementary split-ring resonator (FMCSRR) on the ground plane. The grounded via hole has been used to improve frequency selectivity and out-of-band rejection of the proposed microstrip FPD. The equivalent circuit model compared with full-wave simulation results of the proposed microstrip FPD has been provided. The proposed microstrip FPD has been fabricated and measured, and a good agreement has been found between the simulation and measurement results. The proposed microstrip FPD has a passband covering 2.38–2.45 GHz, and its measured 3 dB fractional bandwidth is about 2.9 %. The total size of the proposed microstrip FPD is 0.17 λ
g × 0.07 λ
g. Compared with other reported FPDs, the presented microstrip FPD has many advantages like compact size, low loss, easy fabrication, extremely sharp rejection skirts around the desired passband and high selectivity.
Psychiatric hospitalizations among adolescents during the pandemic in Italy: a retrospective study
Authors: Di Lorenzo Rosaria , Cutino Anna , Morgante Martina , Panini Giulia , Rovesti Sergio , Filippini Tommaso , Ferri Paola 
Published: October 2024

Abstract

Objectives
The COVID-19 pandemic has negatively impacted child and adolescent mental health. The study outcome was the evaluation of the pandemic impact on adolescents’ hospitalizations in an acute psychiatric ward.

Methods
With an observational and retrospective design, we collected selected variables among adolescents hospitalized in an acute psychiatric ward from 01/07/2017 to 30/06/2022. Data were statistically processed.

Results
Our sample consisted of 118 minors with an average age of 15.7 ± 1.2 SD, mostly represented by females (61 %) and Italians (60.2 %), who made 204 hospitalizations in the study period. The admissions by years drastically decreased in 2020 concomitantly with the lockdown and increased in the first half of 2022. The admission rate was higher in winter and spring, except in 2020 when all admissions decreased (p=0.000). Females more frequently were hospitalized for suicidal behavior and acute anxiety (p=0.000) and were discharged with acute stress reactions, eating disorders, and mood disorder diagnoses (p=0.000). Differently, males more frequently were hospitalized for aggressive behavior (p=0.000) and discharged with ADHD diagnosis (p=0.000). At multiple linear regression, the duration of hospitalization (dependent variable) was negatively associated with “the pandemic period” (p=0.017) and “absent aggressive behavior” (p=0.003), and positively with “autism” diagnosis (p=0.000).

Conclusions
We highlighted the more stressful impact of COVID-19 pandemic on female adolescents, who required more frequently psychiatric hospitalizations due to suicidal behavior, anxiety and mood disorders.
The role of the O2O blended teaching model in improving the teaching effectiveness of physical education classes
Authors: Qiao Honghui 
Published: October 2024

Abstract
The deep fusion of Internet technology and education is constantly pushing forward the reform of university education. Traditional educational ideas, concepts, and models cannot keep pace with the times, and hybrid teaching has become a new way of education in colleges and universities. To improve the teaching effect of physical education classes, the study used a blended teaching model and designed a teaching evaluation and performance prediction model under the blended teaching model based on an improved cluster analysis method and attention mechanism. The lab results indicated that under the blended teaching model, students’ performance increased by 12.89 points, and the level of skill mastery and proficiency increased by 26.52 and 28.55%, respectively, with grades more inclined to high score distribution. “Excellent” grade clustering increased by 77.71%, and “Good” grade clustering increased by 19.01%. The minimum error sum of squares of the improved clustering algorithm was 58.18 and 36.25% lower than the other two algorithms, and the clustering results were more relevant. The two-way attention mechanism algorithm predicted higher accuracy results and performed best on all four evaluation metrics, with a prediction accuracy of 98.23%, an accuracy of 98.42%, and an F1 value of 91.78%. This hybrid teaching model is more in line with the characteristics of the physical education teaching discipline, successfully cultivates students’ independent learning ability, stimulates students’ love for physical education courses, and achieves better teaching results.
Die Muttersprache, die schweigt, und die Stiefmuttersprache, die erzählt. Zu Aharon Appelfelds Sprachpoetik zwischen Deutsch und Hebräisch
Authors: Müller Judith 
Published: October 2024

Abstract
Ausgehend vom Begriff Grenzsprache untersucht der Aufsatz den Appelfeld’schen zentraleuropäischen Raum unter Einbezug der erzählten Sprachen einerseits sowie die Relation von Mehrsprachigkeit, der deutschen und der hebräischen Sprache andererseits. Die hebräischsprachigen Texte Appelfelds behandeln oft deutschsprachige Figuren in einem multilingual geprägten Raum. Im vorliegenden Aufsatz werde ich den Roman כל אשר אהבתי
[Alleswas ich liebte, 1999] analysieren und anhand der Erzählung von Räumen, der Figurensprache und der Thematisierung von Mehrsprachigkeit das Deutsche und weitere Sprachen im Hebräischen hervorheben. Es wird zu beobachten sein, dass sich liminale Lebensformen nicht nur in der Biographie, sondern auch im Schreiben finden: In anderen Worten, die sprachliche Transgression führt zur Schaffung einer persönlichen Literatursprache, die Appelfelds Beziehung zu seinen Sujets aber auch zur Leserschaft prägt.
ImageJ and smartphone app chemistry analyzer using image-based colorimetric assay for quantitative detection of melamine
Authors: Chang Yin-Chiung , Wu Kuo-Hui , Wang Je-Chuang , Huang Wen-Chien 
Published: October 2024

Abstract
A smartphone-assisted microchemistry analyzer with an image-based colorimetric assay using ImageJ and a smartphone app detection method was successfully developed for the quantitative detection of melamine (MEL). The color changes of the MEL in the colloidal gold lateral flow immunoassay strip were captured and analyzed using a smartphone-controlled analyzer with an LED light source and a smartphone camera. The smartphone camera and light source were used to read the colorimetric signal from the strip, and a smartphone app was written and installed onto the smartphone. The quantitative analysis was validated with ImageJ and smartphone app colorimetric analysis. The limits of detection (LODs) for ImageJ and the smartphone app were calculated as 0.30 and 0.07 mg/L, respectively. The highly quantitative relationships between the MEL concentrations and the optical density and gray value of the ImageJ and smartphone app detection method. The designed image-based biosensor is successfully applied to detect MEL in solution of standard MEL and commercial milk samples.
Cutting-edge techniques in low-temperature electrochemical water splitting: advancements in hydrogen production
Authors: Merouani Slimane , Aissa Dehane  , Hamdaoui Oualid 
Published: October 2024

Abstract
This review provides a comprehensive examination of strategies aimed at advancing low-temperature electrolysis for sustainable hydrogen production. It begins by exploring the significance and challenges associated with water splitting, followed by an in-depth discussion on the fundamentals of electrochemical water splitting and crucial performance indicators, including reversible hydrogen electrode potential, specific and mass activities, overpotential, Tafel slope, stability and durability, and Faradaic and energy efficiencies. The article then extensively discusses various emerging strategies, such as decoupled water electrolysis, hybrid water electrolysis (including reagent-sacrificing, pollutant-degrading, and value-added types), tandem water electrolysis, microbial electrolysis cells (covering reactor configurations, electrode materials, microbial populations, and substrates), and the application of external stimuli like ultrasonic, magnetic, and super gravity fields. Additionally, the challenges and advancements in seawater electrolysis are reviewed, with a focus on electrocatalysts, seawater electrolyzers, and future directions. Furthermore, the article addresses current challenges in electrolysis and electrolyzer development, offering perspectives on the future of these techniques. By delving into these strategies, this review aims to contribute to the advancement of clean energy technologies and the transition towards a hydrogen-based economy.
Collaborative online international learning (COIL): an engaging strategy for narrowing learning distances between two continents
Authors: Cardoso Catarina , Duarte Clara C. , Silva Erick J.R. , Fardilha Margarida 
Published: October 2024

Abstract

Objectives
Internationalization is a gold standard of higher education institutions ensuring students’ contact with different environments, including different languages and different cultures. Recently, a universal model has emerged: the Collaborative Online International Learning (COIL), a teaching/learning example of internationalization at home highly driven by the COVID-19 pandemic that boosted online interactions. COIL aims to develop intercultural consciousness and collaborative learning environments among students and faculty from different countries.

Methods
Here we describe and analyze a COIL experience developed between two countries, Portugal and Brazil, in the Biomedical Sciences field with the active participation of approximately 100 undergraduate students. The pedagogical experience was evaluated through different methods including students’ questionnaires which contained qualitative and quantitative evaluations.

Results
Overall, 84.2 % of students rated the COIL experience with the first and second highest ratings (4 and 5, on a 1 to 5 scale), indicating a high overall satisfaction level.

Conclusions
Students considered that there was a mutual exchange and development of new knowledge and acquisition of group work skills despite the time-zone difference.
Algorithm for managing the safety of remote cardiac rehabilitation in the integrated telemedicine system "IS-Cardio"
Authors: Kotelnikova E. V. , Posnenkova O. M. , Bogdanova T. M. , Senchikhin V. N. , Gridnev V. I. 
Published: October 2024

Aim. To testing the safety algorithm of remote cardiac rehabilitation (RCR) programs performed on the basis of the integrated telemedicine system (TMS) "IS-Cardio".Material and methods. The object of a single-center pilot study was the safety algorithm for home physical training (PT) programs embedded in the TMS "ISCardio" cardiac rehabilitation module. Its functionality ensured the implementation of 12-week aerobic PT programs with an intensity of 55-70%, duration 90-300 min/week and a target level of individual exercise tolerance of 8-12 on the 6-20 Borg scale. The number of adverse events was assessed, defined as an individual exercise tolerance level of ³13.Results. The study included 33 patients (men, 75%; mean age, 56±8 years). The activity of patients in the RCR was 2,4±0,7 РT per week with a total duration of 56,5±29,8 min/week. Twelve patients (39,6%) fully completed the PT program, exercising at least 3 times/week for at least 30 min/session. One adverse event was recorded, which required extraordinary transmission of blood pressure, heart rate, ECG recording and remote consultation.Conclusion. The use of TMS with a computerized module for monitoring PT parameters makes it possible to safely perform RCR in patients with cardiovascular disease. The safety of РT programs using an algorithm providing stopping the program with subsequent remote consultation should be ensured. The necessary components of TMS that determine the safety of RCR are the initial stratification of patients, remote monitoring based on self-monitoring devices, and a feedback function.
Troponin I potential in assessing the unfavorable outcome risk in patients with cardiovascular diseases
Authors: Ivanova A. A. , Ievlev R. V. , Kutsenko V. A. , Kapustina A. V. , Imaeva A. E. , Balanova Yu. A. , Metelskaya V. A. , Shalnova S. A. , Drapkina O. O. 
Published: October 2024

Aim. To analyze the associations of high-sensitivity cardiac troponin I (hs-cTnI) levels with outcomes in patients with cardiovascular diseases and to evaluate its prognostic capability for adverse cardiovascular events.Materials and methods. The study included 10688 people aged 35-64 years (59,3% women) who were participants in the ESSE-RF and ESSE-RF2 multi-center observational studies, who had data on the hs-cTnI level. The hs-cTnI level in the specimens was determined with chemiluminescence microparticle immunoassay. From the total sample, groups of people with a coronary artery disease or myocardial infarction (CAD+MI group) and a cerebrovascular accident (CVA group) were identified. The following composite endpoint was chosen: cardiovascular death, non-fatal MI, or non-fatal stroke. The median follow-up period was 7,5 years.Results. A higher hs-cTnI level was associated with an increased likelihood of composite endpoint both in the population sample as a whole (odds ratio (OR)=1,51; 95% CI 1,29-1,79, p<0,001) and in the groups of CAD+MI (OR=1,54; 95% CI 1,23-1,92, p<0,001) and stroke (OR=3,52; 95% CI 1,97-6,29, p<0,001). The threshold values of 4 pg/ml for women and 6 pg/ml for men make it possible to predict adverse outcomes in the groups of CAD+MI and stroke (Area Under the Curve (AUC)=0,8 and 0,89, respectively). Kaplan-Meier survival curves showed significantly lower probability of composite endpoint absence in individuals with hs-cTnI levels ³4/6 pg/ml in both study groups.Conclusion. The study data suggest that hs-cTnI is a promising prognostic biomarker in groups of patients with cardiovascular disease. The selected threshold values make it possible to estimate the probability of an unfavorable outcome in patients CAD, MI, and stroke with high sensitivity and specificity.
2024 Clinical practice guidelines for Stable coronary artery disease
Authors: Barbarash O. L. , Karpov Yu. A. , Panov A. V. , Akchurin R. S. , Alekyan B. G. , Alekhin M. N. , Aronov D. M. , Harutyunyan G. K. , Belenkov Yu. N. , Boytsov S. A. , Boldueva S. A. , Boschenko A. A. , Bubnova M. G. , Bulkina O. S. , Vasyuk Yu. A. , Galyavich A. S. , Glezer M. G. , Golubev E. P. , Golukhova E. Z. , Grinstein Yu. I. , Davidovich I. M. , Yezhov M. V. , Zavadovsky K. V. , Irtyuga O. B. , Karpov R. S. , Koziolova V. V. , Koziolova N. A. , Korennova O. Yu. , Kosmacheva E. D. , Koshelskaya O. A. , Kukharchuk V. V. , Lopatin Yu. M. , Merkulov E. V. , Mironov V. M. , Martsevich S. Yu. , Mirolyubova O. A. , Mikhin V. P. , Nedoshivin A. O. , Nikulina N. N. , Nikulina S. Yu. , Oleinikov V. E. , Panchenko E. P. , Perepech N. B. , Petrova M. M. , Protasov K. V. , Saidova M. A. , Samko A. N. , Sergienko I. V. , Sinitsyn V. E. , Skibitsky V. V. , Soboleva G. N. , Shalaev S. V. , Shaposhnik I. I. , Shevchenko A. O. , Shiryaev A. A. , Shlyakhto E. V. , Chumakova G. A. , Yakushin S. S. 
Published: October 2024

Russian Society of Cardiology (RSC)With the participation of: the National Society for the Study of Atherosclerosis (NOA), the Atherothrombosis National Society, the Russian Association of Cardiovascular Surgeons, the Russian Society of Cardiosomatic Rehabilitation and Secondary Prevention (RosOKR), the Russian Society of Radiologists and Radiologists (RSRR), the Russian Association of Ultrasound Diagnostics Specialists in Medicine (RASUDM), the Russian Scientific Society for X-ray Endovascular Diagnosis and Treatment
2024 Clinical practice guidelines for Hypertension in adults
Authors: Kobalava Zh. D. , Konradi A. O. , Nedogoda S. V. , Shlyakhto E. V. , Arutyunov G. P. , Baranova E. I. , Barbarash O. L. , Bobkova N. V. , Boytsov S. A. , Bubnova M. G. , Vavilova T. V. , Villevalde S. V. , Galyavich A. S. , Glezer M. G. , Grineva E. N. , Grinstein Yu. I. , Drapkina O. M., O. M. , Zhernakova Yu. V. , Zvartau N. E. , Irtyuga O. B. , Kislyak O. A. , Koziolova N. A. , Kosmacheva E. D. , Kotovskaya Yu. V., Yu. V. , Libis R. A. , Lopatin Yu. M. , Nebiridze D. V. , Nedoshivin A. O. , Nikulina S. Yu. , Ostroumova O. D. , Oschepkova E. V. , Ratova L. G. , Salasiuk A. S. , Skibitsky V. V. , Tkacheva O. N. , Troitskaya E. A. , Chazova I. E. , Chesnikova A. I. , Chumakova G. A. , Shalnova S. A. , Shestakova M. V. , Yakushin S. S. , Yanishevsky S. N. 
Published: October 2024

The Russian Society of Cardiology (RKO)With the participation of: Russian Scientific Medical Society of Internal Medicine (RSMSIM)Approved by the Research and Practical Council of the Ministry of Health of the Russian Federation (12.09.2024)