bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between self-efficacy and well-being, and distress, in women with unexplained infertility
Authors: Batinic B. , Lazarevic J. , Dragojevic-Dikic S. 
Published: June 2017

IntroductionOne of the most difficult aspects of unexplained infertility treatments are feelings of uncertainty and the perception that infertility is beyond one's personal control, both of which make the infertility situation more threatening and stressful.ObjectivesThe aim of this study was to explore the correlation between general self-efficacy and infertility specific well-being and distress among women with unexplained infertility.MethodsThe sample consisted of 97 women with unexplained infertility aged between 22 and 46 years old (mean age: 33.58), who were recruited from the obstetrics and gynecology clinic “National front”. Mean duration of conception attempts was 3.10 years. The General Self-Efficacy Scale and the Infertility Specific Well-Being and Distress Scales were applied in the study.ResultsThe mean score on the General Self-Efficacy Scale was 32.77 (SD = 4.624), on the Well-Being scale 3.22 (SD = 0.984) and on the Distress scale 1.94 (SD = 0.754). There was a positive correlation between intensity of infertility specific well-being and general self-efficacy (r = 0.502; P < 0.01) and a negative correlation between infertility specific distress and general self-efficacy (r = −0.265; P < 0.01). Women with unexplained infertility with higher self-efficacy expressed higher levels of well-being and lower levels of distress.ConclusionThe results of our study indicate that women with unexplained infertility who perceive their problems as being beyond their control express higher levels of stress and lower levels of well-being. Psychological treatment of women with unexplained infertility should focus on the aspects that can be influenced through psychotherapy.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Complementary and integrative medicine approach for climacteric disorders
Authors: Gamus D. 
Published: June 2017

IntroductionMenopausal symptom clusters of vasomotor symptoms (VMS), sleep and mood symptoms may last for years and might lead to an increased risk of depression.While hormone replacement therapy is still the most effective therapy for reducing VMS, which are the most prominent symptoms of menopause, the majority of women prefer to choose nonhormonal therapies, either because of medical contraindications or personal beliefs and turn to complementary and integrative medicine (CIM).The objective of this presentation is to review the evidence on nonpharmacologic, nonherbal management treatments of CIM in climacteric disorders.MethodsA systematic review of PubMed database was performed using the key-words: acupuncture, hypnosis, yoga, massage, homeopathy and menopause.ResultsThe research of CIM modalities is evolving. The 2015 position statement of the North American menopause society (NAMS) recommended the use of CBT and hypnosis for the management of VMS. The most recent studies on the effect of acupuncture on VMS however yielded conflicting results: while NAMS concluded that acupuncture is not recommended for managing VMS, later studies produced a positive evidence both for managing of VMS and menopause-related sleep disturbances by this therapeutically modality. There is also some evidence that acupuncture, massage and yoga may alleviate symptoms of depression and that individualized homeopathic treatment may be more effective than placebo for depression in perimenopausal and postmenopausal women.ConclusionsThese findings suggest that acupuncture, hypnosis, yoga, massage and homeopathy may be adopted as a part of multimodal approach in treatment of climacteric disorders.Disclosure of interestThe author has not supplied his/her declaration of competing interest.
Coping behaviors in mothers with an atypical child
Authors: Kékes Szabó M. 
Published: June 2017

Nowadays an increased interest seems to be developing concerning the coping strategies of parents with an autistic child. Several studies focused on the gender differences or tried to explore the effect of the levels of the child's behavioral symptoms. Although most of the previous studies made comparisons at a single point in time, some longitudinal research also came to light in the last decades. The results usually confirmed characteristic patterns of the parents’ coping behavior. The aim of this study was to compare coping behaviors in mothers with a child living with autism spectrum disorder (ASD) or Down-syndrome (DS), since until now there has been no investigation into this question, even though it plays an important role in stressful occasions that are inevitable and frequent concomitants of these families’ life. This time a cross-sectional study has been carried out. The selected research method was composed of semi-structured interviews, self-administered questionnaires and participant observation. 5-5 mothers were involved in the study with a child living with ASD or DS. In addition to this, five mothers with a typically developing child also participated in the research. The age of the children varied between four and nine years. According to the earlier studies, a higher level of stress was experienced by atypical children's mothers, and emotion-focused coping strategies were also more often used by them. Task-focused coping was associated with a lower level of experienced stress in the family system. However, further studies are needed to explore other correlations of the examined field.Disclosure of interestThe author has not supplied his/her declaration of competing interest.
Spectrum of medical and social problems in the female opium addicts
Authors: Shigakova F. 
Published: June 2017

AimThe work was initiated to study peculiarities of medical and social problems of the female opium addiction.Materials and methodsWe examined 56 female opiate addicts aged from 18 to 56 (mean age 31.8 ± 1.09 years) hospitalized at the tertiary detox center (Tashkent). Twenty of the examinees (35.7%) were managed for the first time, 36 patients (64.3%) being treated iteratively.Results and discussionSeventeen women were employed, only three of them were working in their specialization. Thirty-nine patients were either unemployed or engaged in the unskilled labor, that is, the one being out of tune with their education level. Eight examinees served penal servitudes, eleven women being detained without imprisonment. The findings reflect disorders in social adaptation of the most examinees. Drug addiction onset time varied from 19 to 25 years (22.1 ± 1.12 years in the average), but the age range from 20 to 23 was the most frequent one. Duration of episodic taking ranged from 1 month to 2.5 years (2.4 ± 0.7 months in the average). In 10 patients (20%) withdrawal syndrome has formed rapidly, in 1–2 months. Drug dose is partially associated with a patient's ability to pay and heroin accessibility.Almost half of our 56 examinees had drug using husband, cohabitant or sex partner. Quality of remissions was found to greatly depend on a drug using sex partner.ConclusionsMedical and social consequences of the female drug addiction are quite severe to mention early psycho-social disadaptation, prostitution and illegal actions, including thefts, document forgery, drug pushing.Disclosure of interestThe author has not supplied his/her declaration of competing interest.
Group art therapy for the management of fear of giving birth
Authors: Ünsalver B.Ö. , Sezen C. 
Published: June 2017

IntroductionFear of giving birth may affect many pregnant women. Fear of childbirth leads to an increase in C-section demands and the ratio of C-section births. Group therapy addresses at least 8 people at the same time, which both saves time and treatment expenses.ObjectivesThe objective of this study was to evaluate the impact of group art therapy for the management of fear of giving birth.MethodsThirty women volunteers in the third trimester of pregnancy who were attending a public women's hospital and who had fear of giving birth were included in the study. They were randomly distributed to 2 groups. First group (n = 15) received 6 sessions of group art therapy. Second group (n = 15) received 6 sessions of psychoeducation regarding fear of giving birth. Each weekly psychotherapy session lasted 130 minutes.ResultsBy the end of the six weeks Beck depression scale (BDS) scores, Beck Anxiety Scale (BAS) scores and Wijma delivery expectancy/experience questionnaire version A (W-DEQ) scores decreased significantly in the group art therapy group (P < 0.001). In contrast, the psychoeducation group showed no significant changes in terms of BDS, BAS, W-DEQ scores.ConclusionsOur study shows that group art therapy may be a promising cost-effective treatment method to manage fear of giving birth in pregnant women. The study needs to be replicated in women coming from different cultures and socioeconomic statuses to establish group art therapy for the treatment of fear of giving birth.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Playing Video Games – Psychical Threat to Adults?
Authors: Toś M. , Wilk E. , Myszczuk A. , Bratek A. , Krzysztof K. 
Published: June 2017

BackgroundVideo games become increasingly popular form of spending free time, therefore they are often a research subject. Researchers focus mainly on video games influence over children's psyche and their social interactions, although video games can also have an impact on adult's behaviour.ObjectivesIncidence of social anxiety disorder and impulsiveness among video game players and non-players.Material and methodsAn anonymous online survey included 263 students of medical university of Silesia (112 M and 151 W). In study group, 142 people (54%) declared to be players. Questionnaire contained questions about playing time, Barratt Impulsiveness Scale and Liebowitz Social Anxiety Scale. Statistical analyses were performed using the statistical software package Statistica 12.ResultsUsing Liebowitz Scale in 168 (64.86%) all studied people lack of phobia was found, moderate social phobia 39 (15.06%), marked social phobia 26 (10.03%), severe social phobia 17(6.56%) and very severe social phobia 9(3.47%). There was no statistical significance between players and non-players (test Chi2P = 0.6521). Also in Barratt Scale statistical significance was not found in attentional impulsiveness (test U M-W P = 0.3267) and in Motor impulsiveness (test U M-W P = 0.3140). Statistical significance was observed in Non-planning impulsiveness (players: 23.68 V non-players: 22.02; test U M-W P = 0.0036).ConclusionsThe study did not show clear influence adult's video games playing over social phobia and impulsiveness occurrence.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Could Deficits in the Recognition of Emotions that Indicate Social Approval be Associated with Musical Performance Anxiety?
Authors: Osório F.L. , Sabino A.D. , Camargo C.M. 
Published: June 2017

IntroductionProper recognition of facial expressions of emotion is crucial for human social relationships. Impairments in the capacity to process facial information may play an important role in the etiology and maintenance of certain mental disorders, especially music performance anxiety (MPA).ObjectiveTo assess the recognition of facial expressions of emotion in musicians compared to a group of subjects from the general population, considering also the presence/absence of MPA.MethodsHundred and fifty amateur and/or professional musicians who regularly take part in public performances (GM) and 150 subjects from the general population (GP) completed a task of facial emotion recognition and were assessed in terms of accuracy and reaction time. The group of musicians was subdivided between subjects with and without MPA indicators. Data were analyzed using Student's t test (P < 0.05) within the statistical package for the social sciences.ResultsGM were less accurate and had a longer reaction time in the recognition of facial happiness (P < 0.001, effect size: 0.25–0.44) compared to GP. Musicians with MPA had a still lower accuracy in the recognition of happiness, as well as longer reaction times for emotions as a whole (P < 0.04; effect size: 0.32–0.40) compared to musicians without MPA.ConclusionThe poorer performance of musicians in the recognition of happiness suggests difficulties to recognize indicators of social approval, which may negatively affect performance through increased anxiety and negative thoughts that can favor the onset of MPA.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Pharmacogenetic Association Between Glutamatergic Genes and Sri Treatment Response in Obsessive Compulsive Disorder
Authors: Shukla T. , Jabeen Taj R.M.J. , Kulkarni K. , Shetty P. , Viswanath B. , Purushottam M. , Reddy Y.C. , Jain S. 
Published: June 2017

IntroductionPharmacogenetic studies in obsessive-compulsive disorder (OCD) primarily focussing on serotonergic and dopaminergic polymorphisms, provided inconsistent findings. There is recent evidence for glutamatergic abnormalities in OCD.AimsExamine the association glutamatergic genes with serotonin reuptake inhibitor (SRI) response in OCD.ObjectivesTo study pharmacogenetic association between SLC1A1 and GRIN2B polymorphisms with SRI response in OCD.MethodsDSM-IV OCD patients were recruited from a specialty OCD clinic and evaluated using the Yale-Brown obsessive compulsive scale (YBOCS), Mini International Neuropsychiatric Interview (MINI) plus, Clinical Global Impression scale (CGI). They were subsequently reassessed with YBOCS and CGI. To study extreme phenotypes, we included only full responders (> 35% YBOCS improvement and CGI-I score of 1 or 2) to any SRI (n = 191) and non-responders (< 25% YBOCS improvement and CGI-I score ≥ 4) to adequate trial of at least two SRIs (n = 84). Partial responders were excluded. Genotyping was performed using an ABI9700 PCR machine.ResultsGenotype frequencies did not deviate significantly from the values predicted by the Hardy-Weinberg equation. Case-control association analyses revealed no significant association between genotype/allele frequencies with SRI response.ConclusionOur data does not show any association between polymorphisms in glutamatergic genes and SRI response in OCD though such associations have been found in other studies. More SNP's in the same gene could be responsible for the pharmacogenetic associations. More homogenous sample considering symptom dimensions and other phenotypic variables may be needed. It may be critical to go beyond “usual suspect” candidate gene research. In this regard, a novel approach to identify SRI response biomarkers is the use of cellular models.Disclosure of interestThe authors have not supplied their declaration of competing interest.
E-Mental Health for Mental Disorders–Focus on Psychotic Disorders and PTSD
Authors: Gaebel W. 
Published: June 2017

IntroductionE- mental health technologies have developed rapidly over the past years and may support finding solutions to challenges like scarce resources or the treatment gap in psychiatry.ObjectivesProvision of guidance on eMental health technologies in the treatment of post traumatic stress disorder and psychotic disorders.MethodsTwo evidence- and consensus-based EPA Guidance papers on eMental health technologies for the treatment of post-traumatic stress disorder and psychotic disorders were developed.ConclusionsThe evidence on the efficacy of e-mental health interventions for the treatment of PTSD and psychotic disorders is promising. However, more research is needed in the field.Disclosure of interestUnterstützung bei Symposien/Symposia Support− Janssen-Cilag GmbH, Neuss− Aristo Pharma GmbH, Berlin− Lilly Deutschland GmbH, Bad Homburg− Servier Deutschland GmbH, MünchenFakultätsmitglied/Faculty Member− Lundbeck International Neuroscience Foundation (LINF), Dänemark
Serum of Bipolar Patients Induces Pro-inflammatory Activation of Macrophages
Authors: Dubou Serafim S. , Ferrari P. , Colombo R. , Paul Géa L. , Migliorini Parisi M. , Becker M. , Ascoli B.M. , Fries G. , Kauer-Sant’anna M. , Kapczinski F. , Klamt F. , Guma F. T.C.R. , Ribeiro Rosa A. , Barbé-Tuana F.M. 
Published: June 2017

IntroductionEvidence has suggested that immune imbalance is involved with bipolar disorder (BD); however, its precise mechanism is poorly understood.ObjectiveThis study investigated whether biochemical changes in the serum from BD patients could modulate the phenotype of macrophages.MethodsEighteen subjects with BD and healthy individuals (n = 5) were included in this study. The human monocyte cell line U-937 was activated with PMA (phorbol 12-myristate 13-acetate) and polarization was induced with RPMI-1640 media supplemented with 10% serum from each patient for 24 h. Gene expression of selected M1 and M2 markers was assessed by qPCR.ResultsMacrophages exposed to serum of manic and depressive BD patients displayed an increase of IL-1β (6.40 ± 3.47 and 9.04 ± 5.84 versus 0.23 ± 0.11; P < 0.05) and TNF-α (2.23 ± 0.91 and 2.03 ± 0.45 versus 0.62 ± 0.24; P = 0.002 and P = 0.004, respectively) compared to remitted group. In parallel, U-937 macrophages treated with serum of patients in acute episode displayed a down-regulation of CXCL9 (0.29 ± 0.20 versus 1.86 ± 1.61; P = 0.006) and CXCL10 expression (0.36 ± 0.15 and 0.86 ± 0.24 versus 1.83 ± 0.88; P < 0.000 and P = 0.04) compared to remitters.ConclusionsOur results are consistent with previous studies showing that changes in peripheral blood markers could modulate M1/M2 polarization in BD. The evidence of macrophages as source of inflammatory cytokines might be helpful to unravel how the mononuclear phagocyte system can be involved in the etiology of BD.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Bipolar Disorder and Cannabis
Authors: Jmii G. , Zghal M. , Ghali F. , Mezghenni M. , Jouini L. , Robbana L. , Ellouze F. , Mrad F. 
Published: June 2017

IntroductionPeople with bipolar disorder frequently struggle with substance abuse and dependence. Typically, cannabis is the most commonly abused drug in individuals with bipolar disorder. Some investigators have implied that cannabis may actually be mood stabilizing in patients with bipolar disorder. However, the relationships between cannabis use and bipolar disorders are complex and remain incompletely described.ObjectiveThe aim of this study was to identify the characteristics of addiction to cannabis in bipolar patients type I and determine the consequences of cannabis on the expression of bipolar illness and prognosis.MethodsThis is a comparative cross-sectional study which included patients followed in the psychiatry department of the G Razi hospital for bipolar disorder type I and for substance dependence according to DSM IV diagnostic criteria. Hetero-questionnaire on sociodemographic variables, clinical and treatment.ResultsThe average age was 41 years. The average hospital stay was 9.18 days. 33.33% of patients were monitored regularly. Most patients were single and worked as a day labourer. Cannabis was the most consumed substance. Cannabis use was prior to the expression of psychiatric illness in 55% of cases. The average number of hospitalisation in patients with a cannabis addiction was significantly greater than that observed in the non-addicted group. Similarly, the average number of suicide attempts among patients with cannabis addiction was significantly higher than the group without cannabis addiction.ConclusionsAggressive drug abuse treatment immediately after a first psychiatric hospitalisation might decrease rates of recurrence and new cases of cannabis use disorder in the course of bipolar disorder.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Caregiver Depression Screening in a Child and Adolescent Clinic Seeking Consultation for their Children with Attention-deficit/Hyperactivity in Oman
Authors: Balushi N. Al , Samir A.A. 
Published: June 2017

IntroductionStudies have shown that caregivers of children with (ADHD) are at a higher risk of mood disorders such as depression. The presence of mood disorders among the caregivers of children with ADHD has negative repercussion in terms of prognostic indicator, utilization of the health care service and the resultant quality of life.ObjectivesTo solicit the performance of indices of depression among caregivers of children with ADHD and to explore the relationship between severity of mood score, subtypes of ADHD and socio-demographic factors.MethodsA cross-sectional study conducted in a tertiary hospital in Oman dispensing child and adolescent mental health services. Arabic-version of PHQ-9 was used screen for the presence of depression among the caregivers of children diagnosed with ADHD based on DSM 5. The severity and subtypes of ADHD were quantified using Vanderbilt ADHD Parent/Teacher Rating Scale. Socio-demographic background and clinical data were gathered from medical records or attending caregivers.ResultsThe study included 100 caregivers of children with ADHD. Most of the primary caregivers were mothers (92%). Using the cutoff score of 12 on the PHQ-9, rates of depression for the mother was 14%. Some socio-demographic factors were strongly associated with severity of depressive symptom.ConclusionThis study suggests that depressive symptoms as elicited by PHQ-9 are common among caregivers of children with ADHD. The rate of depressive symptoms is higher compared to the general population in Oman. This study lays groundwork for contemplating mechanisms to mitigate depressive symptoms among caregivers of children with ADHD.Disclosure of interestThe authors have not supplied their declaration of competing interest.
Cognitive Vulnerability to Depression in Adolescents with Depression, their Healthy Siblings and a Control Group: A Cross-sectional Study
Authors: Chartier G. , Garel P. , Herba C. , Booij L. 
Published: June 2017

IntroductionAt least half of first depressive episode appear before adulthood. A negative cognitive bias is present among individuals who suffer from major depression. This bias is also reported among individuals at high risk of major depression (e.g. child of depressed mother). When present, cognitive vulnerability may predispose to major depression. No study to date aimed to evaluate the cognitive vulnerability of siblings of depressed individuals.Objectives and aimsTo review the principles behind cognitive vulnerability. To assess cognitive vulnerability in depressed adolescents, in healthy siblings and in a control group.MethodsEighty adolescents (27 adolescents treated for depression, 24 healthy siblings and 29 controls), aged between 12 and 20 years old, were recruited and assessed using validated measures of bio-psycho-social vulnerabilities. All diagnoses were confirmed using a K-SADS interview. Cortisol level samples were obtained through morning saliva. Cognitive vulnerability was assessed using self-report questionnaires (CES-D, LEIDS-R, EPQ) as well as computer-based tasks (Ekman's tasks of facial recognition and the movie for assessment of social cognition [MASC]). We translated the MASC from German to French. The parents of the adolescents also filled the LEIDSR and the CESD.ResultsThe LEIDS-R presented a significant increase in certain subscales (hopelessness, aggression and rumination) compared to the healthy siblings and the controls. Interestingly, there was also a correlation between the LEIDS R results of the parents and of the depressed adolescent (r = 0.43, P = 0.04).ConclusionsThe LEIDSR appears to be the most sensitive task to detect cognitive vulnerability. A relation between the parent response and the depressed adolescent response could be found.Disclosure of interestThe authors have not supplied their declaration of competing interest.