bluuebunny/crossref_metadata_2025_split huggingface dataset:
The TEND (Tomorrow's Expected Number of Discharges) Model Accurately Predicted the Number of Patients Who Were Discharged from the Hospital the Next Day
Authors: van Walraven Carl , Forster Alan J. 
Published: October 2017

BACKGROUNDKnowing the number of discharges that will occur is important for administrators when hospital occupancy is close to or exceeds 100%. This information will facilitate decision making such as whether to bring in extra staff, cancel planned surgery, or implement measures to increase the number of discharges. We derived and internally validated the TEND (Tomorrow's Expected Number of Discharges) model to predict the number of discharges from hospital in the next day.METHODSWe identified all patients greater than 1 year of age admitted to a multisite academic hospital between 2013 and 2015. In derivation patients we applied survival‐tree methods to patient‐day covariates (patient age, sex, comorbidities, location, admission urgency, service, campus, and weekday) and identified risk strata having unique discharge patterns. Discharge probability in each risk strata for the previous 6 months was summed to calculate each day's expected number of discharges.RESULTSOur study included 192,859 admissions. The daily number of discharges varied extensively (median 139; interquartile range [IQR] 95‐160; range 39‐214). We identified 142 discharge risk strata. In the validation patients, the expected number of daily discharges strongly predicted the observed number of discharges (adjusted R2 = 89.2%; P < .0001). The relative difference between observed and expected number of discharges was small (median 1.4%; IQR ‐5.5% to 7.1%).CONCLUSIONThe TEND model accurately predicted the daily number of discharges using information typically available within hospital data warehouses. Further study is necessary to determine if this information improves hospital bed management.
How Coordination Trajectories Influence the Performance of Interorganizational Project Networks
Authors: Oliveira Nuno , Lumineau Fabrice 
Published: October 2017

This study examines how the joint use of integrators and contracts either enables or hampers coordination and, in turn, the performance of interorganizational project networks. Using extensive qualitative analyses and sociometric techniques, we investigated coordination among organizations during seven small- and medium-sized building projects. Our longitudinal study reveals how integrators develop connecting functions that, together with contracts’ steering functions, largely drive coordination dynamics. Further data analyses provide insight into how coordination hinges on the prevalence of connecting or steering, which may more or less fit with coordination needs in various project phases. Given these findings, we theorize the contingent nature of the interplay between the use of integrators and contracts throughout projects. Our findings are integrated into a process model of how coordination trajectories lead to different performance levels of interorganizational project networks. Our study has theoretical implications for the literature on project-based organizing and, more broadly, the literature on interorganizational coordination.The online appendix is available at https://doi.org/10.1287/orsc.2017.1151 .
Art and the Public Sphere: From controversy to opinion formation in the making of contemporary art
Authors: Jordan Mel 
Published: October 2017

Abstract
W. J. T. Mitchell first coupled the terms ‘Art’ and the ‘Public Sphere’ in 1992 in the title of his edited book Art and the Public Sphere (1992). The volume was based on the one-day symposium Art and Public Spaces: Daring to Dream.1 Mitchell’s conception of Art and the Public Sphere is specifically addressed by his editorial ‘Introduction: Utopia and critique’ and is further developed in his chapter in the same volume, ‘The violence of public art’. Mitchell’s pairing of public sphere theory with public art is based on a semiological account of artworks; thus he places significance on the interpretation of the meanings constructed from artworks and how various speculations on an artwork’s ‘meaning’ generate conversations in the public realm. I argue that this emphasis limits the way in which we consider the production and function of art because it forces a type of ontological engagement with public art that foregrounds the question ‘what is art of?’ rather than ‘what does art do?’. Mitchell’s account can be considered a public sphere insofar as it causes discussion in the public realm; however, I believe that there is more to be gained for art’s social and political significance if we consider how art functions for opinion formation. I propose that art also operates towards the construction of culture and society rather than simply reflecting upon it. And following Georg W. Bertram, I consider Walter Benjamin’s formation of ‘critical practice’, which proposes that critique is essentially a change of practice as opposed to a negation of society.
“Los indios estaban cabreros”. Historia, sociedad y políticas de la historia en los cambios del relato escolar sobre la conquista de América
Authors: De Amézola Gonzalo 
Published: October 2017

Este trabajo se propone describir el drástico cambio de sentido en el relato de la conquista de América registrado en las últimas dos décadas, que pasó de un tradicional hispanismo acrítico -predominante desde principios del siglo XX hasta los inicios de la década del 90 de esa misma centuria- a una interpretación fuertemente indigenista e igualmente ingenua en los últimos veinte años. Esta inversión de la interpretación se explica en buena medida por las innovaciones en la enseñanza de la Historia impulsadas por las reformas educativas promovidas por la Ley Federal de Educación (1993) y la Ley de Educación Nacional (2006) pero se relaciona también con transformaciones producidas en la sociedad y en la dimensión política e ideológica que hicieron posible esa mutación en la percepción del problema. Asimismo, se intenta de establecer algunas conclusiones sobre los logros y las limitaciones de este reciente tratamiento escolar de la conquista. En el desarrollo del trabajo se emplearán como fuentes la legislación educativa, los nuevos diseños curriculares, otras medidas de política educativa, manuales escolares y encuestas a alumnos secundarios de instituciones públicas y privadas.
Iconology, visual culture and media aesthetics
Authors: Mitchell William John Thomas 
Published: October 2017

The article contains fragments of three chapters form the book Image Science. Iconology, Visual Culture and Media Aesthetics (Chicago 2015), titled The are no Visual Media , Back to the Drawing Board and Foundational Sites and Occupied Spaces . W. J. T. Mitchell created in his previous works the key concepts which imply an approach to images as true objects of investigation – an “image science”. Author, continuing with his influential line of thoughts, amplifies interdisciplinary studies of visual media. The chapters also delve into such topics as conections between new media and architecture or the occupation of space in contemporary popular uprisings. Image science is a call for a method of studying images that overcomes the “two-culture split” between the natural and human sciences.
Coincidence of Numerical Abbreviations in the Western Paulines
Authors: Cole Zachary J. 
Published: October 2017

AbstractThis study tests the possibility that the presence of numerical shorthand in a literary manuscript can hold genealogical significance. The number-writing techniques of a family of New Testament manuscripts are compared, concentrating on coincidental usage of alphabetic numerals in specific passages. It is shown that some - though not all - scribes mimicked the distinctive number-styles of their Vorlage(n), which suggests that in certain cases such abbreviations can function as visual indications of a manuscript’s genealogy.
Einige Überlegungen zum Wort mÈDr „Ohr = Henkel“ im demotischen P.Berlin 6848, 1/21
Authors: Bojowald Stefan 
Published: October 2017

AbstractThis contribution deals with a new analysis of a passage in the Demotic P. Berlin 6848. The focus is on the metaphorical meaning „handle“ for the word „ear“, which has already been assumed by the papyrus’ editors. The likelihood of this interpretation is increased here by examples in the Akkadian, Aramaic and Arabic languages, in which the same association can be found.
P.Oxy. 2174 fr. 5: an Odyssey for Hipponax?
Authors: Prodi Enrico Emanuele 
Published: October 2017

AbstractThis article re-examines P.Oxy. 2174 fr. 5 (Hipponax fr. 74 West = Degani), offers an improved transcription of its text, and questions its relevance to the other fragments of the papyrus, suggesting instead that it may belong to a papyrus of the Odyssey.
Arsinoa-Anagram in Callimachus’ Ektheosis Arsinoes
Authors: Danielewicz Jerzy 
Published: October 2017

AbstractIn the text of the Ektheosis Arsinoes, as we have it, the name of the title character does not appear at all. Although it may be the result of the poem’s fragmentary state of preservation, it seems to be consistent with Callimachus’s stylistic preferences. This article suggests that the missing name ARSINOA can be detected in an anagram hidden in the first half of line 46.
Ἀσπάζομαι Εὐπρέπειαν καὶ πάντας
Authors: Laudenbach Benoît 
Published: October 2017

AbstractThis article is an edition of a 5th century Greek private letter on papyrus, from a Christian context, sent from Alexandria. Written by a son to his mother through another person, the letter is typical of Christian Greek epistolography (Christian turns of phrase, judicial proceedings, food purchase, condolences, formulae valetudinis). It also mentions the St-John’s martyrium of Alexandria.
Five Private Letters on Papyrus in the British Library
Authors: Zellmann-Rohrer Michael W. 
Published: October 2017

AbstractA first edition of five private letters on family and business matters, dating between the second and seventh centuries CE. Of particular note are mentions of the management of ousiac land (text no. 2), a petition before the dux in connection with misappropriation of barley imported to an oasis (no. 4) and, possibly, an imperial visit to Egypt (no. 3).
The Impact of Fiscal Transparency on Corruption: An Empirical Analysis Based on Longitudinal Data
Authors: De Simone Elina , Gaeta Giuseppe Lucio , Mourão Paulo Reis 
Published: October 2017

Abstract
Fiscal transparency is considered an essential feature of public financial management and is supposed to provide beneficial governance effects such as reducing corruption. This paper adds to recent empirical literature that specifically investigates the impact of fiscal information disclosure on corruption. Country-level evidence provided by previous studies is exclusively based on cross-sectional econometric analyses, while the present contribution relies on a wide-ranging, country-level dataset of 116 countries that cover a ten-year time span (2003–2012), and on dynamic panel data estimates. These innovations in terms of data and methods provide new, robust empirical support to the claim that fiscal transparency is negatively correlated with corruption.
PARP-1 and PARP-2 activity in cancer-induced cachexia: potential therapeutic implications
Authors: Barreiro Esther , Gea Joaquim 
Published: October 2017

Abstract
Skeletal muscle dysfunction and mass loss is a characteristic feature in patients with chronic diseases including cancer and acute conditions such as critical illness. Maintenance of an adequate muscle mass is crucial for the patients’ prognosis irrespective of the underlying condition. Moreover, aging-related sarcopenia may further aggravate the muscle wasting process associated with chronic diseases and cancer. Poly(adenosine diphosphate-ribose) polymerase (PARP) activation has been demonstrated to contribute to the pathophysiology of muscle mass loss and dysfunction in animal models of cancer-induced cachexia. Genetic inhibition of PARP activity attenuated the deleterious effects seen on depleted muscles in mouse models of oncologic cachexia. In the present minireview the mechanisms whereby PARP activity inhibition may improve muscle mass and performance in models of cancer-induced cachexia are discussed. Specifically, the beneficial effects of inhibition of PARP activity on attenuation of increased oxidative stress, protein catabolism, poor muscle anabolism and mitochondrial content and epigenetic modulation of muscle phenotype are reviewed in this article. Finally, the potential therapeutic strategies of pharmacological PARP activity inhibition for the treatment of cancer-induced cachexia are also being described in this review.
A novel design of HA-coated nanoparticles co-encapsulating plasmid METase and 5-Fu shows enhanced application in targeting gastric cancer stem cells
Authors: Yang Weifeng , Zhang Houting , Xin Lin 
Published: October 2017

Abstract
Nanoparticles (NPs) are recognized as an attractive vehicles for cancer treatment due to their targeted drug release. Gastric cancer is an important killer disease, and its therapy methods still need improvement. The NPs were prepared using a precipitation method, and were evaluated using transmission electron microscopy (TEM). MTT and Transwell assays were used to determine cell viability and apoptosis. In vivo experiments were performed to validate the effects of NPs on tumor growth. Methioninase (METase)/5-Fu co-encaspulated NPs showed highest ζ size and lowest ζ potential than other NPs. The migration and tumorsphere formation ability of CD44(+) was stronger than CD44(−). The effects of METase/5-Fu co-encaspulated NPs on inhibition cell growth was stronger than that of 5-Fu encaspulated NPs, while HA coated NPs showed significant target ability than that NPs without HA. METase supplementation promoted the inhibition effect of 5-Fu on thymidylate synthetase (TS), as well as cell apoptosis. The in vivo experiments demonstrated that HA coated NPs significantly inhibited tumor growth. It was concluded that HA-coated NPs enhance the target ability, while METase/5-Fu co-encaspulated NPs promote the inhibition effects on tumor growth in gastric cancer.
Numerical Simulation of a Kinetic Cell for in-situ Combustion. A Parametric Study and History Matching Aspects
Authors: Aguilar-Madera Carlos G. , Molina-Espinosa L. , Velasco-Tapia F. 
Published: October 2017

Abstract
The in-situ combustion method is an enhanced oil recovery technique based on the injection of air in petroleum reservoirs with the aim to burn a portion of hydrocarbons. This reduces the oil viscosity improving substantially the oil mobility. Simultaneously other phenomena take place as: distillation, segregation, oil upgrading, among others. In this work, a mathematical model to simulate oil combustion for kinetic cell experiments is presented. The model includes four-phases, nine components and four chemical reactions: coke formation, heavy oil fraction combustion, light oil fraction combustion and coke combustion. This formulation is commonly used to simulate in-situ combustion projects at combustion tubes- and petroleum reservoir-scales. The mass and energy balances were formulated leading to one set of highly coupled ordinary differential equations, which was numerically solved. The predictive model capabilities were tested by comparison with lab data, and it was found that CO and CO2 productions, oxygen uptake and cell temperature evolution agree well with experimental results. At one preliminary stage, the parameters fitting experimental results were inferred by individual manipulation until the best results were found. These parameters were perturbed in order to identify those parameters dominating the global dynamic of process. We found that energy activations and the mass density of oil components are the dominant parameters. We suggest that history matching processes must be focused over these parameters, and for this end, the implementation of advanced computational routines to solve multivariable inverse problems is recommended. In this work, we developed two automatic history matching techniques: one process based on Newton’s method and the second one based on evolutionary algorithms. The Newton’s method showed problems to find the minimum error, meanwhile the evolutionary algorithm was able to optimize the dominant parameters, but at the expense of slow convergence.
In vitro
ovicidal activity of poly lactic acid curcumin-nisin co-entrapped nanoparticle against Fasciola spp. eggs and its reproductive toxicity
Authors: Oyeyemi Oyetunde , Adegbeyeni Odunayo , Oyeyemi Ifeoluwa , Meena Jairam , Panda Amulya 
Published: October 2017

Abstract

Background:
Curcumin and nisin have been widely reported for their antibacterial and anticancer potency. However, their therapeutic applications are hampered by several factors, which necessitate their development into nanosize ranges for improved delivery and activities. Their incorporation into a single nanosynthesized form may suggest desirable efficacy on parasites. The aim of the study was to assess the ovicidal activity of the curcumin-nisin polylactic acid (PLA) entrapped nanoparticle on the Fasciola eggs and its reproductive toxicity.

Methods:
The nanoparticle was formulated by double emulsion method. The eggs of the adult Fasciola spp. were exposed to different concentrations (0.3125–5 mg/mL) of the nanoparticle to monitor hatchability. Mice were exposed to 0.5 mL of the formulated drug at varying concentrations (10–20 mg/kg) and then sacrificed for sperm morphology assay.

Results:
The mean particle size, polydispersity index, and drug entrapment efficiency of the formulated drug were 288.4±24.3 nm, 0.232, and 51.7%, respectively. The highest nanoparticulate concentration (5 mg/mL) showed the least percentage egg hatching (41.7%) compared with the other treatment groups and positive control (albendazole) (45.1%). The aberrations observed in sperm cells were not concentration-dependent and no significant differences were observed in the mean aberrations between the nanoparticulate drug-exposed groups and the negative control (p>0.05).

Conclusions:
The results confirmed the ovicidal activity of the curcumin-nisin nanoparticulate drug against the Fasciola species. The formulation also showed no toxicity to sperm cells. More robust studies on anti-fascioliasis activity of the drug on adult Fasciola spp. and in vivo and in vitro toxicity studies are recommended.
Congenital cataract with LSS gene mutations: a new case report
Authors: Chen Xiaodan , Liu Li 
Published: October 2017

AbstractBackground:Congenital cataract is one of the major causes of blindness and amblyopia in children. About one-third of the cases are inherited.Case presentation:We applied whole exome sequencing for a pediatric patient with congenital cataract, small penis, baldness and absence of eyebrows and detected a compound heterozygous mutation in the lanosterol synthase (Conclusions:We concluded that the mutations affect the structural stability of the protein to some extent.
Hepatitis C virus exposure rate among health-care workers in rural Lower Egypt governorates
Authors: Elbahrawy Ashraf , Elwassief Ahmed , Abdallah Abdallah Mahmoud , Kasem Arafat , Mostafa Sadek , Makboul Khaled , Ali Mohamed Salah , Alashker Ahmed , Eliwa Ahmed Maher , Shahbah Hossam , Othman Mohamed Abdellah , Morsy Mohamed Hanafy , Abdelbaseer Mohamed Ali , Abdelhafeez Hafez 
Published: October 2017

Abstract

Background and Objectives
Studies on hepatitis C virus (HCV) in Egypt supported a strong role for various exposures in the health-care setting. In this study, we attempted to estimate the frequency of HCV exposure among Egyptian health-care workers (HCWs).

Methods
Five hundred and sixty-four (564) HCWs were included in this study. Two hundred and fifty-eight (45.74%) were health-care providers and 306 (54.25%) were non-health-care providers. All HCWs completed both the study questionnaire and provided a blood sample for anti-HCV testing by third-generation enzyme-linked immunosorbent assay. Subsequently, anti-HCV-positive samples were tested for HCV RNA using nested polymerase chain reaction (PCR).

Results
The mean age of included HCWs was 33.0 ± 9.8 years; of them, 319 (56.56%) were males and 245 (43.44%) were females. The mean duration of health-care work was 9.3 ± 6.7 years. The frequency of antibody against hepatitis C virus (anti-HCV) among included HCWs was 8.7% (n = 49). Old age and prolonged duration of health-care work were significantly associated with anti-HCV seropositivity. Forty (81.63%) of 49 with anti-HCV-positive HCWs had positive hepatitis C viremia. The frequency of HCV RNA positivity increased with age. The frequency of eradicated past infection among nurses (36.85%) was markedly higher than that (6.7%) detected in non-health-care providers.

Conclusion
High rate of HCV infection is detected in Egyptian HCWs in rural Lower Egypt governorates. Health-care providers seem to eradicate HCV infection more frequently than non-health-care providers. National screening and treatment of infected HCWs are recommended.
Colorectal stenting for obstruction due to retrorectal tumor in a patient unsuitable for surgery
Authors: Ersan Veysel , Kutlu Ramazan , Erdem Ceyhun , Karagul Servet , Kayaalp Cuneyt 
Published: October 2017

Abstract
Fund of knowledge on palliative treatment of unresectable retrorectal tumors is scare. Here, we reported a non-surgical treatment of a huge retrorectal malignant tumor in an aged and debilitated patient complicated with colorectal obstruction. An 86-year-old male with severe comorbidities was admitted with acute colorectal obstruction owing to an untreated retrorectal malign epithelial tumor. There was a lobulated retrorectal mass, 20 cm × 15 cm at largest size, extending to the superior iliac bifurcation level, caused an obstruction of the rectal lumen. He was not suitable for surgical excision because of the severe comorbidities. Rectal obstruction was palliated by two self-expandable metallic stents. He tolerated the procedures well and post-procedural course was uneventful. After four months, stents were patent and the patient was continent. Stenting for colorectal obstruction owing to a retrorectal tumor can be feasible in patients who are not suitable for surgery (aged, debilitated, advanced tumor). It avoided the surgical trauma to a high-risk patient and ensured the continuity of continence. As far as we know, this was the first report on colorectal stenting for a retrorectal tumor.
Copper nanoparticles as an alternative feed additive in poultry diet: a review
Authors: Scott Abdullah , Vadalasetty Krishna Prasad , Chwalibog André , Sawosz Ewa 
Published: October 2017

Abstract
Copper (Cu) is a vital trace element involved in various physiological and biochemical processes. However, animals can only absorb a small fraction of Cu and the most is excreted, contaminating soil and aquatic environment. Hence, the use of this mineral as a growth promoter is today one of the crucial health and environmental concerns. In recent years, many studies have reported Cu nanoparticles (Cu-NP) as a promising alternative to antibacterial reagents and a growth promoter. Depending on the size, shape, dose and animal species, Cu-NP exhibit a variety of effects on animal performance. Apart from being highly bioavailable, reports have already pointed out the growth-promoting, antibacterial and immune-modulatory effects of Cu-NP. Toxicological studies provide varied results in animal models. However, other studies being undertaken in different animal species have shown the promise of Cu-NP supplementation. Therefore, there is a need to optimise the dose and duration of Cu-NP supplementation for livestock, depending on their biological effects. Moreover, the bioavailability of Cu-NP in livestock still needs further confirmation. In this review, we summarise the benefits and hazardous effects of Cu-NP and the possibility of using Cu-NP as a feed supplement in different animals, in general, and in poultry particularly.