bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of a Referral‐Only Policy on Wait Time for Outpatient Pediatric Dermatology Appointments
Authors: Herd Tiffany J. , Nopper Amy J. , Horii Kimberly A. 
Published: March 2017

AbstractDecreasing wait time for pediatric dermatology appointments is important to patients. We retrospectively examined the effect of a referral‐only policy on patient wait time for an initial appointment in an academic pediatric dermatology clinic and found a statistically significant decrease in wait time after the policy was instituted.
Dermatomyofibromas Arising in Children: Report of Two New Cases and Review of the Literature
Authors: Ma Janice E. , Wieland Carilyn N. , Tollefson Megha M. 
Published: March 2017

AbstractDermatomyofibroma is a rare, benign mesenchymal proliferation not commonly reported in children. Two patients with biopsy‐proven dermatomyofibroma were identified (one female, one male) at our institution, both with rather atypical clinical presentations. The clinical and histopathologic findings and a review of the literature are presented here. Features of dermatomyofibroma should be recognized and differentiated from those of similar‐appearing entities since the prognosis of this benign tumor is favorable after complete excision.
Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft‐Versus‐Host Disease
Authors: Theiler Martin , Oza Vikash S. , Mathes Erin F. , Dvorak Christopher C. , McCalmont Timothy H. , Yeh Iwei , Sidbury Robert , Cordoro Kelly M. 
Published: March 2017

AbstractEosinophilic pustular folliculitis (EPF) is a rare cutaneous disorder that typically occurs in three clinical contexts: men, individuals who are immunosuppressed or have human immunodeficiency virus, and infants. A fourth subtype occurring 2 to 3 months after hematopoietic stem cell transplantation (HSCT) has recently been described in several adults. We report two cases of EPF arising in children after HSCT. It is important to recognize this form of EPF after HSCT and differentiate it from graft‐versus‐host disease since it responds readily to topical steroids and appears to have an excellent prognosis.
Recent Research Developments Affecting Nonlife Insurance—The CAS Risk Premium Project 2014 Update
Authors: Eling Martin , Jia Ruo 
Published: March 2017

AbstractThis article discusses the main results of the Casualty Actuarial Society Risk Premium Project 2014 update. It reviews the recent research developments in the process of nonlife risk assessment. Of special note, systemic risk continuously attracts a great deal of attention. In the past year, reinsurance studies have increased significantly, driven by progress in optimal reinsurance design and reinsurance asymmetric information. Both topics show the academic reflection of financial crisis in the field of risk and insurance. The evaluation of reserves and the methods mitigating asymmetric information have also received a great deal of attention.
Periorbital melasma: Hierarchical cluster analysis of clinical features in Asian patients
Authors: Jung Y. S. , Bae J. M. , Kim B. J. , Kang J.‐S. , Cho S. B. 
Published: March 2017

BackgroundStudies have shown melasma lesions to be distributed across the face in centrofacial, malar, and mandibular patterns. Meanwhile, however, melasma lesions of the periorbital area have yet to be thoroughly described.MethodsWe analyzed normal and ultraviolet light‐exposed photographs of patients with melasma. The periorbital melasma lesions were measured according to anatomical reference points and a hierarchical cluster analysis was performed.ResultsThe periorbital melasma lesions showed clinical features of fine and homogenous melasma pigmentation, involving both the upper and lower eyelids that extended to other anatomical sites with a darker and coarser appearance. The hierarchical cluster analysis indicated that patients with periorbital melasma can be categorized into two clusters according to the surface anatomy of the face. Significant differences between cluster 1 and cluster 2 were found in lateral distance and inferolateral distance, but not in medial distance and superior distance. Comparing the two clusters, patients in cluster 2 were found to be significantly older and more commonly accompanied by melasma lesions of the temple and medial cheek.ConclusionOur hierarchical cluster analysis of periorbital melasma lesions demonstrated that Asian patients with periorbital melasma can be categorized into two clusters according to the surface anatomy of the face.
Grass filter strip residence time‐trap efficiency relationship
Authors: Akan A. Osman , Atabay Serter 
Published: March 2017

AbstractThis paper investigates the relationship between trap efficiency and residence time in vegetative filter strips under unsteady flow conditions. A mathematical model, based on a kinematic‐wave formulation of overland flow and a mass balance equation for suspended sediments, is employed. An empirical equation is used to estimate sediment removal. The governing equations are written and solved numerically in terms of a set of dimensionless variables. The results indicate that the relationships between the trap efficiency and residence time depend on the shape of the inflow hydrograph. Further analysis of results identified another non‐dimensional parameter that can predict the trap efficiency if only the volume and the peak rate of inflow are known. While the mathematical model employed includes many elements of the sophisticated vegetative filter strip models previously reported, the resulting charts are as easy to use as the oversimplified design methods currently in use
Barriers to innovation in human rabies prophylaxis and treatment: A causal analysis of insights from key opinion leaders and literature
Authors: van de Burgwal L. H. M. , Neevel A. M. G. , Pittens C. A. C. M. , Osterhaus A. D. M. E. , Rupprecht C. E. , Claassen E. 
Published: March 2017

SummaryRabies is an essentially 100% fatal, zoonotic disease, caused by Lyssaviruses. Currently, the disease is vaccine‐preventable with pre‐ and post‐exposure prophylaxis (PrEP and PEP). Still, rabies virus is estimated to cause up to 60,000 human deaths annually, of which the vast majority occurs in rural Asia and Africa, due to the inaccessibility of prophylaxis and non‐existence of treatment. Despite these unmet clinical needs, rabies control mainly focuses on the sylvatic reservoir and drug innovation receives relatively little attention compared to other neglected tropical diseases (NTDs). As such, the lag of innovation in human rabies prophylaxis and treatment cannot be explained by limited return on investment alone. Strategies countering rabies‐specific innovation barriers are important for the acceleration of innovation in human rabies prophylaxis and treatment. Barriers throughout society, science, business development and market domains were identified through literature review and 23 semi‐structured interviews with key opinion leaders worldwide. A subsequent root cause analysis revealed causal relations between innovation barriers and a limited set of root causes. Finally, prioritization by experts indicated their relative importance. Root causes, which are fundamental to barriers, were aggregated into four types: market and commercial, stakeholder collaboration, public health and awareness, and disease trajectory. These were found in all domains of the innovation process and thus are relevant for all stakeholders. This study identifies barriers that were not previously described in this specific context, for example the competition for funding between medical and veterinary approaches. The results stress the existence of barriers beyond the limited return on investment and thereby explain why innovation in human rabies medication is lagging behind NTDs with a lower burden of disease. A re‐orientation on the full spectrum of barriers that hinder innovation in rabies prophylaxis and treatment is necessary to meet unmet societal and medical needs.
Equations, Contractions, and Unique Solutions
Authors: Sangiorgi Davide 
Published: March 2017

One of the most studied behavioural equivalences is bisimilarity. Its success is much due to the associated bisimulation proof method, which can be further enhanced by means of “bisimulation up-to” techniques such as “up-to context.”
A different proof method is discussed, based on a unique solution of special forms of inequations called contractions and inspired by Milner’s theorem on unique solution of equations. The method is as powerful as the bisimulation proof method and its “up-to context” enhancements. The definition of contraction can be transferred onto other behavioural equivalences, possibly contextual and non-coinductive. This enables a coinductive reasoning style on such equivalences, either by applying the method based on unique solution of contractions or by injecting appropriate contraction preorders into the bisimulation game.
The techniques are illustrated in CCS-like languages; an example dealing with higher-order languages is also shown.
Visual Loss from Choroidal Melanoma Mimicking Neurological Syndromes
Authors: Hammamji Karim , Reich Ehud , Arora Amit , Cohen Victoria M.L. , Sagoo Mandeep S. 
Published: March 2017

Melanoma of the eye is rare, but can mimic a range of disorders. This report highlights 2 cases of choroidal melanoma with vision loss mimicking neurological diagnoses. The first patient is a 41-year-old white male with a known history of multiple sclerosis and a previous episode of optic neuritis in the right eye, who presented with a 6-month history of decreased vision in the same eye, and occasional photopsiae. He was treated with 2 courses of oral steroids for presumed recurrent optic neuritis. After a temporary improvement in his symptoms, his vision worsened, following which he had a head MRI, which revealed a solid intraocular mass. He was subsequently diagnosed with a choroidal melanoma for which he was treated successfully with ruthenium-106 plaque brachytherapy. The second patient is a 57-year-old female, who presented with a progressive cerebellar syndrome under investigation by the neurology service, as well as decreased vision in the right eye. Her visual acuity gradually deteriorated and her neurological assessment, which included a PET-CT, revealed uptake in the right eye. The diagnosis of a choroidal melanoma was made, and following conservative treatment with proton beam radiotherapy, she had an enucleation of the eye. Intraocular tumours can masquerade as many different entities. Unexplained unilateral visual loss, especially if it is atypical for a neurological syndrome, should prompt dilated fundoscopy and referral to an ophthalmologist.
The Science of William M. Gray: His Contributions to the Knowledge of Tropical Meteorology and Tropical Cyclones
Authors: Klotzbach Philip J. , Chan Johnny C. L. , Fitzpatrick Patrick J. , Frank William M. , Landsea Christopher W. , McBride John L. 
Published: March 2017

AbstractAdvances in knowledge in tropical meteorological research are discussed in the context of contributions made by Professor William M. Gray. Gray pioneered the compositing approach to observational tropical meteorology through assembling of global radiosonde datasets and tropical cyclone research flight data. In the 1970s, he made fundamental contributions to knowledge of convective–larger-scale interactions. Throughout his career, he wrote seminal papers on tropical cyclone structure, cyclogenesis, motion, and seasonal forecasts. His conceptual development of a seasonal genesis parameter also laid an important framework for both seasonal forecasting as well as climate change studies on tropical cyclones. His work was a blend of both observationally based studies and the development of theoretical concepts. This paper reviews the progress in knowledge in the areas where Dr. Gray provided his largest contributions and describes the scientific legacy of Gray’s contributions to tropical meteorology.
A New Method to Correct Radiosonde Temperature Biases Using Radio Occultation Data
Authors: Tradowsky Jordis S. , Burrows Chris P. , Healy Sean B. , Eyre John R. 
Published: March 2017

AbstractA new method to estimate radiosonde temperature biases using radio occultation measurements as a reference has been developed. The bias is estimated as the difference between mean radio occultation and mean radiosonde departures from collocated profiles extracted from the Met Office global numerical weather prediction (NWP) system. Using NWP background profiles reduces the impact of spatial and temporal collocation errors. The use of NWP output also permits determination of the lowest level at which the atmosphere is sufficiently dry to analyze radio occultation dry temperature retrievals. The authors demonstrate the advantages of using a new tangent linear version of the dry temperature retrieval algorithm to propagate bending angle departures to dry temperature departures. This reduces the influence of a priori assumptions compared to a nonlinear retrieval. Radiosonde temperature biases, which depend on altitude and the solar elevation angle, are presented for five carefully chosen upper-air sites and show strong intersite differences, with biases exceeding 2 K at one of the sites. If implemented in NWP models to correct radiosonde temperature biases prior to assimilation, this method could aid the need for consistent anchor measurements in the assimilation system. The method presented here is therefore relevant to NWP centers, and the results will be of interest to the radiosonde community by providing site-specific temperature bias profiles. The new tangent linear version of the linear Abel transform and the hydrostatic integration are described in the interests of the radio occultation community.
Climatology of Size, Shape, and Intensity of Precipitation Features over Great Britain and Ireland
Authors: Fairman Jonathan G. , Schultz David M. , Kirshbaum Daniel J. , Gray Suzanne L. , Barrett Andrew I. 
Published: March 2017

Abstract
A climatology of precipitation features (or objects) from the Great Britain and Ireland radar-derived precipitation mosaic from 2006 to 2015 is constructed, with features defined as contiguous areas of nonzero precipitation rates. Over the 10 years, there are 54 811 747 nonunique precipitating features over 100 km2 in area, with a median precipitation feature area of 249 km2, median major axis length of 29.2 km, median aspect ratio of 2.0:1, median feature mean precipitation rate of 0.49 mm h−1, and median feature maximum precipitation rate of 2.4 mm h−1. Small-scale precipitating systems are most common, but larger systems exceeding 10 000 km2 contribute close to 70% of the annual precipitation across the study region. Precipitation feature characteristics are sensitive to changes in annual and diurnal environment, with feature intensities peaking during the afternoon in summer and the largest precipitation features occurring during winter. Precipitation intensities less than 5 mm h−1 comprise 97.3% of all precipitation occurrences and contribute 83.6% of the total precipitation over land. Banded precipitation features (defined as precipitation features with aspect ratio at least 3:1 and major axis length at least 100 km) comprise 3% of all precipitation features by occurrence, but contribute 23.7% of the total precipitation. Mesoscale banded features (defined as banded precipitation features with major axis length at least 100 km and total area not exceeding 10 000 km2) and mesoscale convective banded features (defined as banded precipitation features with at least 100 km2 of precipitation rates exceeding 10 mm h−1) are most prevalent in southwestern England, with mesoscale convective banded features contributing up to 2% of precipitation.
Ensemble Probabilistic Prediction of a Mesoscale Convective System and Associated Polarimetric Radar Variables Using Single-Moment and Double-Moment Microphysics Schemes and EnKF Radar Data Assimilation
Authors: Putnam Bryan J. , Xue Ming , Jung Youngsun , Snook Nathan A. , Zhang Guifu 
Published: March 2017

Abstract
Ensemble-based probabilistic forecasts are performed for a mesoscale convective system (MCS) that occurred over Oklahoma on 8–9 May 2007, initialized from ensemble Kalman filter analyses using multinetwork radar data and different microphysics schemes. Two experiments are conducted, using either a single-moment or double-moment microphysics scheme during the 1-h-long assimilation period and in subsequent 3-h ensemble forecasts. Qualitative and quantitative verifications are performed on the ensemble forecasts, including probabilistic skill scores. The predicted dual-polarization (dual-pol) radar variables and their probabilistic forecasts are also evaluated against available dual-pol radar observations, and discussed in relation to predicted microphysical states and structures.
Evaluation of predicted reflectivity (Z) fields shows that the double-moment ensemble predicts the precipitation coverage of the leading convective line and stratiform precipitation regions of the MCS with higher probabilities throughout the forecast period compared to the single-moment ensemble. In terms of the simulated differential reflectivity (ZDR) and specific differential phase (KDP) fields, the double-moment ensemble compares more realistically to the observations and better distinguishes the stratiform and convective precipitation regions. The ZDR from individual ensemble members indicates better raindrop size sorting along the leading convective line in the double-moment ensemble. Various commonly used ensemble forecast verification methods are examined for the prediction of dual-pol variables. The results demonstrate the challenges associated with verifying predicted dual-pol fields that can vary significantly in value over small distances. Several microphysics biases are noted with the help of simulated dual-pol variables, such as substantial overprediction of KDP values in the single-moment ensemble.
Sustainable Climate Change Adaptation in Indian Country
Authors: McNeeley Shannon M. 
Published: March 2017

AbstractMuch of the academic literature and policy discussions about sustainable development and climate change adaptation focus on poor and developing nations, yet many tribal communities inside the United States include marginalized peoples and developing nations who face structural barriers to effectively adapt to climate change. There is a need to critically examine diverse climate change risks for indigenous peoples in the United States and the many structural barriers that limit their ability to adapt to climate change. This paper uses a sustainable climate adaptation framework to outline the context and the relationships of power and authority, along with different ways of knowing and meaning, to illustrate the underpinnings of some tribes’ barriers to sustainable climate adaptation. The background of those structural barriers for tribes is traced, and then the case of water rights and management at the Wind River Reservation in Wyoming is used to illustrate the interplay of policy, culture, climate, justice, and limits to adaptation. Included is a discussion about how the rulings of the Big Horn general stream adjudication have hindered tribal climate change adaptation by limiting the quantity of tribal reserved water rights, tying those rights to the sole purposes of agriculture, which undermines social and cultural connections to the land and water, and failing to recognizing tribal rights to groundwater. Future climate projections suggest increasing temperatures, and changes in the amount and timing of snowpack, along with receding glaciers, all of which impact water availability downstream. Therefore, building capacity to take control of land and water resources and preparing for climate change and drought at Wind River Reservation is of critical importance.
Differential Aging in Place and Depressive Symptoms: Interplay Among Time, Income, and Senior Housing
Authors: Park Sojung , Kim BoRin , Han Yoonsun 
Published: March 2017

Objective: We examined cumulative and differential experiences of aging in place. Method: Data came from the 2002 and 2010 wave of the Health Retirement Study. We modeled the trajectory of later-life depressive symptoms, and how senior-housing environments moderate the negative association between economic disadvantages and depressive symptoms. Results: At baseline, economically disadvantaged older adults were more likely to exhibit depressive symptoms. However, detrimental effects of income group (non-low income vs. moderate income; non-low income vs. low income) on depressive symptoms did not significantly change over time. The age-leveler hypothesis may account for nonsignificant effects of disadvantaged income groups over time. Discussion: Findings suggest that moderate-income seniors may experience positive differentials if they age in place in a supportive senior-housing environment. Moderate-income seniors may have broader opportunities in senior housing compared to private-home peers. Senior housing might partially counter risks such as low mental health, emerging from life-course disadvantage.
Dual task training in persons with Multiple Sclerosis: a feasability randomized controlled trial
Authors: Sosnoff Jacob J , Wajda Douglas A , Sandroff Brian M , Roeing Kathleen L , Sung JongHun , Motl Robert W 
Published: March 2017

Objective: To determine the feasibility of dual task training in persons with Multiple Sclerosis. Design: Randomized, single-blinded controlled trial. Setting: University research laboratory. Participants: A total of 234 individuals inquired about the investigation. After screening, 20 individuals with multiple sclerosis who self-reported problems with multitasking and were ambulatory volunteered for the investigation. 14 participants completed the post-assessment following the 12-week intervention. Intervention: Participants were randomly assigned to either single task training program which focused on balance and walking function ( n=6) or dual task training program that incorporated cognitive tasks in balance and walking training ( n=8). Measures: Before and after the 12-week interventions participants underwent assessments of walking; dual task walking; balance (Berg Balance Scale and balance confidence) and cognition as indexed by the Brief International Cognitive Assessment for MS. Results: There was an 8.5% recruitment rate, a 70% retention rate, and a 100% adherence rate. There was a trend for dual task gait speed to improve in the dual task training group following the intervention (Pre: task 1: 109.8±39, task 2: 104.2±34.1; Post: task 1:127.6±40.1, task 2: 122.8±37.4; P=0.14; η2 = 0.24). There was also a trend for the dual task training group (28.1) to have greater performance than the control group (24.7) on visuospatial memory ( P=0.10; η2= 0.23). There were no changes in cognitive performance during walking trials. Conclusions: The study procedures were found to be feasible and improvements should be made in recruitment efforts going forward. Further examination of dual task training programs in individuals with multiple sclerosis is warranted.