bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized Controlled Trial for Helicobacter pylori Eradication in a Naive Portuguese Population: Is Sequential Treatment Superior to Triple Therapy in Real World Clinical Setting?
Authors: Boal Carvalho Pedro , Magalhães Joana , Dias de Castro Francisca , Rosa Bruno , Cotter José 
Published: April 2017

Introduction: Helicobacter pylori eradication has become increasingly difficult as resistances to several antibiotics develop. We aimed to compare Helicobacter pylori eradication rates between triple therapy and sequential therapy in a naive Portuguese population.Material and Methods: Prospective randomized trial including consecutive patients referred for first-line Helicobacter pylori eradication treatment. Exclusion criteria: previous gastric surgery/neoplasia, pregnancy/lactancy, allergy to any of the drugs. The compared eradication regimens were triple therapy (pantoprazol, amoxicillin and clarithromycin 12/12 hours, 14 days) and sequential therapy (pantoprazol 12/12 hours for 10 days, amoxicillin 12/12 hours for days 1 - 5 and clarithromycin plus metronidazol 12/12 hours during days 6 - 10). Eradication success was confirmed with urea breath test. Statistical analysis was performed with SPSS v21.0 and a p-value < 0.05 was considered statistically significant.Results: Included 60 patients, 39 (65%) female with mean age 52 years (SD ± 14.3). Treatment groups were homogeneous for gender, age, indication for treatment and smoking status. No statistical differences were encountered between sequential and triple therapy eradication rates (86.2% vs 77.4%, p = 0.379), global eradication rate was 82%. Tobacco consumption was associated with a significantly lower eradication success (54.5 vs 87.8%, p = 0.022).Discussion: In this randomized controlled trial in a naive Portuguese population, we found a satisfactory global Helicobacter pylori eradication rate of 82%, with no statistical differences observed in the efficacy of the treatment between triple and sequential regimens.Conclusion: These results support the use of either therapy for the first-line eradication of Helicobacter pylori.
Fatores Associados a Tensão Arterial Não Controlada em Pessoas com Diabetes Tipo 2 Seguidas nos Cuidados de Saúde Primários em Portugal
Authors: Rosendo Inês , Santiago Luiz Miguel , Marques Margarida 
Published: April 2017

Introdução: A hipertensão arterial está associada a maior morbimortalidade na diabetes tipo 2. É assim importante identificar quais as características socio demográficas, hábitos e fatores de risco das pessoas com diabetes tipo 2 que estão associadas a descontrolo tensional de modo a intervir de forma ajustada nesta população.Material e Métodos: Estudo observacional transversal nos cuidados de saúde primários com recolha de dados de pessoas com diabetes tipo 2 aleatorizadas pelos seus médicos de família, estratificados proporcionalmente pelas cinco regiões de saúde de Portugal continental. Variáveis: tensão arterial, idade, sexo, formação, duração da diabetes, HbA1c, hábitos tabágicos, peso, perímetro abdominal, nível de atividade física e adesão à medicação. Análise bivariada e por regressão logística para avaliar a associação independente de cada variável com descontrolo tensional (tensão arterial ≥ 140/90).Resultados: Estudados 709 doentes, 60,2% homens, idade média 66,12 ± 10,47 anos. Após análise de regressão logística, verificou-se que os fatores independentemente associados a não controlo da tensão arterial foram a menor formação académica (p = 0,014), a menor duração da diabetes (p = 0,002), o maior perímetro abdominal (p < 0,001), a maior pressão de pulso (p < 0,001) e o maior nível de atividade física (p = 0,043), assim como o facto de ser fumador (p < 0,001).Discussão: As principais limitações do estudo são o facto da amostra não ser totalmente aleatória e incluir apenas frequentadores dos cuidados primários, um possível vies inter-observador e o facto de ser um estudo transversal e não poder deduzir causalidade.Conclusão: O sub-grupo de pessoas com diabetes tipo 2 identificadas como tendo maior associação a pior controlo tensional deveriam ser alvo de uma abordagem diferente e mais intensiva nos cuidados de saúde primários em relação a este fator de risco. Recomendamos estudos longitudinais e populacionais para confirmar estes resultados.
Metodología para la virtualización computacional de espacios físiscos de la Universidad EAN
Authors: Ardila José , Dorado Ruben 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
Este artículo presenta una metodología enfocada a proyectos de virtualización de espacios físicos. Con virtualización se hace referencia a proyectos en los que se digitaliza de manera interactiva un lugar físico. La metodología se presenta de manera detallada, así como algunos problemas que generalmente se presentan junto con sus posibles soluciones.
Smoothing methods for the treatment of digital texts
Authors: Dorado Ruben 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
This article describes the exploration task known as smoothing for statistical language representation. It also reviews some of the state- of-the-art methods that improve the representation of language in a statistical way. Specifically, these reported methods improve statistical models known as N-gram models. This paper also shows a method to measure models in order to compare them.
Unsupervised acquisition of a markov model for word correction using Wikipedia
Authors: Dorado Rubén 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
This paper presents a work in progress on the area of automatic acquisition of corpora for spelling correction. Wikipedia contains a high quantity of information including relationships between concepts and named annotations. However, it also contains linguistic information such as misspellings written by many of the Wikipedia collaborators. In this paper, we propose an efficient method to analyze the link structure of Web-based dictionaries to construct a list of misspelled words and their corrections. The method is currently being researched and applied to the Wikipedia as a corpus.
La rentabilidad de secar con altas temperaturas los productos del repintado automotriz
Authors: Castaño Iván Danilo 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
Los talleres especializados en la reparación de lámina y pintura de los automóviles, tienen la obligación de ofrecer calidad a sus clientes, lo que implica tener un proceso estandarizado donde la técnica y equipamiento se deben complementar eficientemente. El repintado de automóviles involucra variables tanto físicas como químicas que inciden directamente en el tiempo que se invierte para culminar el proceso satisfactoriamente. En este artículo se analizan cuáles son los parámetros operativos a tener en cuenta para la selección de un horno para el repintado de automóviles, que permita optimizar los tiempos de secado, manteniendo la calidad y respetando los plazos de entrega al cliente.
Separación de una mezcla binaria etanolagua en columna de destilación de platos UDCC por densimetría
Authors: Suárez Cerquera Aidé , Castillo Acosta Camilo Andrés 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
Durante esta investigación se logró separar una mezcla binaria Etanol-Agua al 50% en volumen en el equipo <<columna de destilación de platos EDIBON UDCC 0014/07>>. Durante el proceso se realizaron varias tomas de muestra en el calderín y en el depósito de recogida del producto destilado; la columna de destilación se encuentra controlada desde un computador con sistema SCADA y control PID, desde donde se controlaron las variables de vacío, caudal y temperatura de la máquina para así obtener varias concentraciones de la muestra a través de un tiempo determinado; en el proceso fue de vital importancia que el sistema se encontrara presurizado, debido a que al no haber la presión suficiente la destilación pudiera tardar más tiempo de lo esperado. Se pudo realizar una recuperación del etanol hasta en un 76.6% en volumen lo cual indicó que fue un proceso muy satisfactorio ya que esta concentración es la alcanzada por un alcohol etílico comercial de uso farmacéutico.
Toma de decisiones en escenarios complejos
Authors: Pérez Alcázar Jorge Augusto , Redondo Johan Manuel 
Published: April 2017

ONTARE. REVISTA DE INVESTIGACIÓN DE LA FACULTAD DE INGENIERÍA
En este trabajo se presenta una metodología novedosa para la toma de decisiones basada en la dinámica del sistema y los sistemas dinámicos. Aquí se muestra cómo el diagrama de bifurcaciones es en realidad un mapa de todos los escenarios posibles. Esta herramienta es muy importante para los gerentes y los administradores públicos, porque el ejercicio de la toma de decisiones se torna más sencillo cuando la comprensión del problema se ve mejorada. En este documento mostraremos algunos alcances de esta metodología usando como ejemplo un modelo para la creación de empresas en una zona industrial.
A Comparison of Mixed Gas Foams with N2 and CO2 Foam Fracturing Fluids on a Flow Loop Viscometer
Authors: Harris P. C. 
Published: April 2017

ABSTRACT
A study of the rheological properties of mixed gas foams was conducted on a flow loop viscometer. Variables studied included different ratios of N2 and CO2 in 70-quality foams, base gel concentration, crosslinking agent, and temperature.
The rheological properties of mixed gas foams are very similar to the rheologies of N2 and CO2 foams. This was anticipated, since the rheologies of N2 and CO2 foams are similar. The exact static stability behavior of these foams was not anticipated. Pure CO2 70-quality foams have four to five times the static half-life as pure N2 70-quality foams. Replacement of CO2 by N2 in a 70-quality foam decreased the half-life of the foam. The inclusion of only 20-quality N2 in a 70-quality mixed gas foam decreased the foam stability to equal a pure N2 70-quality foam. We saw no evidence that addition of N2 to a CO2 foam improved its stability.
Previously published foam rheology equations for N2 and CO2 foams1,2 were found to be valid, and only minor adjustment to a few coefficients were needed to include the effects of mixed gases. A BASIC program is included which allows foam viscosity to be calculated as a function of quality, gas type and concentration, external liquid phase power law parameters n' and K', shear rate, and temperature.
Fluid loss characteristics of mixed gas foams were found to be the same as for N2 or CO2 foams.
Nanosafety: Towards Safer Nanoparticles by Design
Authors: Bastús Neus G. , Puntes Víctor 
Published: April 2017

Background:
Nanosafety aims for a solution through the safer design (and re-design) of
nanostructured materials, optimizing both performance and safety, by resolving which structural features
lead to the desired properties and modifying them to avoid their detrimental effects without losing
their desired nanoscale properties in the process. Starting with known toxic NPs, the final aim
should be the re-design of such detrimental specific NP characteristics and to redefine the way they
should be manipulated from the beginning to the end of their life cycle.

Methods:
The researchers reviewed literature in the area of novel nanosafety strategies addressing the
“safe-by-design” paradigm.

Results:
The potential hazards of engineered NPs are not only determined by the physicochemical
properties of the engineered NPs per se but also on the interactions of these NPs with immediate surrounding
environments. The aim of promoting the timely and safe development of NPs cannot be
achieved via traditional studies as they address one material at one time. The development of a safer
design strategy of engineered NPs requires an understanding of both intrinsic (synthetic) properties
together with their extrinsic responses to external stimuli.

Conclusions:
We have summarized recent developments of novel nanosafety strategies addressing the
“safe-by-design” paradigm for optimizing both performance and safety, allowing the comparison of
results of different studies and ultimately providing guidelines for the re-design of safer NPs. The resulting
discussion is intended to provide guidelines for synthetic nanochemists on how to design NPs
to be safe during their full life cycle while maintaining their parental desired properties.
Occlusal caries risk assessment using Cariogram analysis in student aged 11-12 years
Authors: Wardani Riana , Zubaedah Cucu , Setiawan Asty Samiaty 
Published: April 2017

ABSTRACT Introduction: Basic Health Research 2013 showed Dental Caries Index in school age student in West Java was lower than the expected target, with occlusal surface as most affected part. The purpose of this study was to determine the risk status of dental caries in school age student by using cariogram analysis. Methods: Observational research. Study was conducted on 30 student aged 11-12 years with caries high risk on occlusal surfaces. Purposive sampling was taken from students of SDN Cikawari and SDN Mekarjaya Bandung Regency with high DMF-S index. Inclusion criteria: male and female, aged 11-12 years, good systemic health, SDN Mekarjaya and SDN Cikawari Bandung Regency students. Exclusion criteria: suffering from systemic disorder, currently in long-term antibiotic therapy, orthodontic appliance usage. Case history, eating habits and intake of fluoride, caries experience, salivary volume and buffering capacity of each sample was examined using cariogram examination method. Results: The cariogram analysis showed 43% chance of caries avoidance. Diet control was 23.3%, includes two factors: sugary foods and eating frequency. Bacteria control was 11.9% by evaluating both bacterial factors (the amount of plaque and the bacteria Streptococcus mutans). Vulnerability control was 14.4%, including caries prevention by the continuation of fluorine program and other conditions control that affect salivary secretions. Conclusion: Based on cariogram analysis found that all samples who had occlusal surfaces caries were at a high risk category, but still having moderate potential of avoiding new caries occurrence by controlling risk factors.Keywords: Cariogram analysis, Occlusal caries, Aged 11-12 years
Oral manifestations of anemia in HIV/AIDS patients without ARV treatment
Authors: Hidayat Wahyu , Dewi Tenny Setiani , Wisaksana Rudi 
Published: April 2017

AbstractIntroduction: Acquired immunodeficiency syndrome (AIDS) is a set of symptoms caused by decreases of the immune system that was infected by human immunodeficiency virus (HIV). Blood disorders often found in patient with HIV and associated with HIV infection. Mostly found disorders is anemia of chronic disease. The prevalence of anemia in HIV/AIDS patients reaches 70%. Oral manifestations of anemia are atrophy of the papillae on tongue, glossodynia, pallor, angular cheilitis, glossitis, aphthous ulcers/erosive lesions, candidiasis, and geographic tongue. There are many publications that uses anemia as indicator to determine the prognosis of HIV infection, thus the description of oral manifestation of anemia in the non-ARV HIV/AIDS patients is a necessity. The purpose of this study was to describe the oral manifestation of anemia in the non-ARV HIV/AIDS patients. Methods: The methods used were purposive random sampling. Samples were new HIV/AIDS patients who have not got antiretroviral (ARV) treatment. The study included 40 patients in Teratai Clinic Hasan Sadikin Hospital Bandung. Results: Oral manifestations of anemia were found amongst non-ARV HIV/AIDS patients, which were candidiasis in 37 patients, glossodynia in 28 patients, glossitis in 10 patients, and angular cheilitis in 1 patient. Conclusion: From the study found that oral manifestations of anemia that found in non-ARV HIV/AIDS patients were candidiasis, glossodynia, glossitis and angular cheilitis. HIV/AIDS patients with anemia needed to treat more intensive for better prognosis and quality of life.Keywords: Anemia, HIV/AIDS, Candidiasis, Glossitis, Glossodynia
“E ERA UMA VEZ UMA MENINA CHAMADA MARIA”...: A INOVAÇÃO NA TELEDRAMATURGIA BRASILEIRA.
Authors: Silva Rosângela Barbosa da 
Published: April 2017

Este artigo debruça-se na minissérie hoje é dia de Maria, texto de Carlos Alberto Soffredine, sob a luz dos conceitos de Gérard Genette. Busca-se, assim, uma reflexão sobre a estrutura das narrativas no que concerne à inovação na teledramaturgia brasileira. Para tanto, foram analisadas cinco cenas da minissérie que norteiam o presente estudo. Hoje é dia de Maria apresenta aspectos inovadores no que diz respeito à construção narrativa, sobretudo no uso de diversas temporalidades, ao mesmo tempo em que retomou, em termos de abordagem temática e de estilo. Pode-se verificar a criação de uma nova linguagem ficcional que fez uso de diversos tipos de discursos que foram do popular ao erudito, apresentando uma nova forma de se recriar a narrativa televisiva, fazendo uso da intertextualidade.
Molecular Diagnostics in Colorectal Cancer
Authors: YS Rustam Effendi , Rey Imelda 
Published: April 2017

Colorectal cancer (CRC) presents in one of three patterns: sporadic colorectal cancer in those without a family history (65-85%); those with a family history (familial CRC) 10-25% of cases; inherited CRC accounting for less of 10% cases and presents as well-characterized cancer predisposition syndromes including Lynch syndrome (hereditary non-polyposis colorectal cancer/HNPCC) which comprises about 1-5% of all colorectal cancer, and multiple polyps CRC, which includes familial adenomatous polyposis (FAP,1%), rare CRC syndrome 0.1 %). Many efforts have been made to discover the genetic and molecular features of CRC, and there is more evidence that these features determine the prognosis and response to treatment. Colorectal cancer (CRC) is a heterogeneous disease, with three known major molecular groups. The most common is the chromosomal instability group, characterized by an accumulation of mutations in specific oncogens and tumor suppressor genes. The second is the microsatellite instability group, caused by the dysfunction of deoxyribonucleic acid (DNA) mismatch repair genes leading to genetic hypermutability. The CpG island methylation phenotype (CIMP) is the third group, distinguished by hypermethylation. In this review we would like to provide an up-to-date overview of molecular genetic aspects of CRC that are currently important and should guide clinical practice in colorectal cancer in the diagnosis and selection of therapy.
Avaliação da Efetividade da Intervenção Breve para a Prevenção do Uso de Álcool no Trabalho
Authors: Ferreira Maira Leon , Albertoni Maiara Rosa , Silva Nayara Baptista , Sartes Laisa Marcorela Andreoli 
Published: April 2017

O uso de álcool está relacionado a acidentes de trabalho, absenteísmo e piora da saúde do indivíduo. Objetivos: Realizar um estudo piloto para avaliar a efetividade da Intervenção Breve (IB) no contexto laboral para o uso de álcool. Método: Realizou-se um ensaio clínico randomizado não controlado, quantitativo. Um total de 104 participantes fizeram parte do estudo. A metodologia utilizada foi a Screening, Brief Intervention, and Referral to Treatment (SBIRT). Resultados: O grupo 02 (IB) reduziu significativamente o consumo de álcool e o grupo 01 (Feedback/ panfletos) não apontou diferenças significativas. Porém os dois grupos sinalizaram tendências para a redução do consumo. Conclusão: A aplicação da IB no ambiente de trabalho foi viável. Novas pesquisas são necessárias a fim de comprovar a eficácia e efetividade desta intervenção neste contexto.
A criança enquanto condição do sujeito em Freud: apontamentos para uma clínica psicanalítica com crianças
Authors: Barbosa Jane Mara dos Santos , Chaves Wilson Camilo 
Published: April 2017

Tratamos nesse trabalho da contribuição de Freud para a clínica psicanalítica com crianças ao trazer em sua obra apontamentos essenciais para o atendimento como a saída para as dificuldades da criança associar livremente, bem como a peculiaridade do vínculo transferencial estabelecido por ela. Utilizando a análise do caso Hans, Freud orienta o pai da criança na condução da análise da fobia do filho e em Além do princípio do prazer, Freud acentua a importância do discurso do brincar na elaboração dos conflitos psíquicos apresentados pelo sujeito na condição de criança.
Parentalidade em casais homossexuais: Uma revisão sistemática
Authors: Araldi Marina Ortolan , Serralta Fernanda Barcellos 
Published: April 2017

A pesquisa visa compreender como a parentalidade em casais homossexuais é investigada na literatura científica através de uma revisão sistemática. Para tanto, foram selecionados 17 artigos publicados entre 2004 e 2014, nas bases de dados SciELO, PePSIC e Academic Search Premier, em inglês, espanhol, português e francês, com os descritores homosexual parent OR same-sex parent OR homoparental. Resultados indicam que as pesquisas tentam responder como é a parentalidade em casais que diferem da norma a partir do viés heteronormativo. Sendo assim, a edificação da homossexualidade como patologia em décadas anteriores e a permanência desta visão dificultam a revisão de tais conceitos a nível social. Por isto a importância de estudos que gerem uma nova compreensão sob esta população.
Significados de paternidade em famílias monoparentais femininas
Authors: Cúnico Sabrina Daiana , Arpini Dorian Mônica 
Published: April 2017

O presente estudo teve como objetivo conhecer os significados atribuídos à paternidade por mulheres chefes de família. Participaram deste estudo dez mulheres que compunham uma família monoparental e eram provenientes de grupos populares A entrevista, com roteiro semiestruturado, foi um dos instrumentos de coleta de dados assim como o grupo focal. O material coletado foi analisado por meio da análise de conteúdo, que sustentou o surgimento de categorias de análise. Os resultados indicaram, de modo geral, a coexistência de concepções tradicionais e modernas no que se refere aos significados atribuídos à paternidade. Ademais, evidenciou-se uma tendência a ampliação do modelo de paternidade, no qual o pai além de provedor da família é reconhecido por sua presença e afetividade, resgatando a sua importância no ambiente familiar.
Anticancer activity, phytochemical screening and acute toxicity evaluation of an aqueous extract of Aristolochia longa L.
Authors: Benarba Bachir , Pandiella Atanasio , Elmallah Almahy 
Published: April 2017

Aristolochia longa (Aristolochiaceae) is widely used in traditional medicine. The present study was carried out to investigate the cytotoxic activity and the acute toxicity of an aqueous extract of A. longa roots. Also, the phytochemical composition of the extract was evaluated. The cytotoxic effects of the aqueous extract in triple negative breast cancer MDA-MB-231 and HBL-100 cell lines was evaluated by MTT assay. A. longa roots were screened for the presence of phytochemical constituents using the standard qualitative phytochemical procedures. The acute oral toxicity (5000 mg/kg limited dose test) was evaluated. Our results showed that both cells were inhibited in a dose-dependent manner by A. longa aqueous extract. The IC50 of A. longa aqueous extract was estimated after 72h treatment at 40μg/ml and 97μg/ml in HBL100 and MDA-MB-231 cell lines, respectively. A. longa aqueous extract at a concentration of 500μg/ml suppressed effectively the cell growth of HBL100 and MDA-MB-231 cells. TLC analysis revealed the presence of flavonols, flavones and/or flavonoid glycosides as major compounds in the extract. Results of the acute toxicity study suggest the non-toxicity of the A. longa aqueous extract to the liver. Interestingly, the renal function was not affected by the extract administration at 5000mg/kg. A. longa aqueous extract could be toxicologically safe when administered orally in rats in a single dose. A. longa could be considered as a promising and safe source for developing novel therapeutics against breast cancer. Keywords: Aristolochia longa, breast cancer, phytochemical, acute toxicity, TLC.