bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningioma gigante como causa de alterações psiquiátricas: Relato de caso
Authors: Zanatelli Marcelo Motta , Brumatti Jorge Ismael , Zanatelli Filipe Mota 
Published: January 2018

ResumoMuitos dos pacientes neurológicos procuram auxílio médico devido a sintomas inespecíficos e subjetivos, nem sempre possíveis de diagnóstico claro e imediato. Dentre tais lesões, os tumores de crescimento lento como os meningiomas estão entre os mais encontrados. Pela acomodação cerebral peritumoral, esses tumores podem atingir volumes extremamente grandes com pouco ou nenhum sintoma associado. Relatamos o caso de paciente que estava sob medicação antipsicótica para tratamento de alterações comportamentais, atendido na Santa Casa de Misericórdia de Santos após crise convulsiva e traumatismo cranioencefálico. Durante a avaliação tomográfica foi encontrado volumoso tumor frontal com lise óssea e extensão para gálea e subcutâneo. Foi submetido à craniotomia eletivamente com ressecção completa da lesão de aproximadamente 9 cm e 145 gramas. O paciente recebeu alta no oitavo dia pós-operatório, consciente, orientado e sem sequelas neurológicas. Este relato visa atentar sempre para uma possível lesão ainda não identificada nos casos de pacientes com sintomas inespecíficos neurológicos, devendo a tomografia computadorizada de crânio, procedimento relativamente simples e quase sempre disponível, ser usada para tal fim.
Scoliosis: current overview and treatment considerations
Authors: da Silva Elton Gomes , Kojo Hamilton D. , Joaquim Andrei Fernandes , Shaffrey Christopher I. 
Published: January 2018

AbstractScoliosis presents with lateral curvature of the spine greater than 10 degrees in x-ray and it can be associated with others deformities of the curvature of the spine. The management of this deformity is dependent of the classification and clinical presentation of the patient. This paper purposes to discuss to the initial evaluation of patients with scoliosis, distinguishing the different types of scoliosis and the management of patients with this diagnosis.
Subdural arachnoidal cyst of the spinal cord: etiology, clinical presentation, surgical strategy and results
Authors: Fonseca Joelton , Lynch José Carlos , Policarpo Fabiana , Esteves Celestino , Bomfim Cleber , Welling Leonardo 
Published: January 2018

Abstract
Objective: Of this study is identifying the clinical manifestations, discuss the etiology, and present the surgical treatment nuances and outcomes of patients with sub dural arachnoidal cysts (AC). Method: A retrospective study was carried out with 7 consecutives patients with spinal cord subdural AC, diagnosed, evaluated and operated at the Neurosurgical department of Servidores do Estado Hospital, from 1996 to 2010. The radiological studies, patient records, surgical descriptions and surgical videos, were reviewed, creating a database from which information was collected. The follow-up varied from 2 to 168 months (mean, 48 months). All cysts were histopathological verified. Results: Five AC were located on the thoracic spinal cord, one were located anterior in the cervical region, and one at the lumbar spinal level. The complete resection of the cyst was performed in 4 surgeries. Three patients had cysts located ventral to the cord, which precluded complete excision. The symptoms in four patients demonstrated major improvement. There was no operative death in this series, there was no major complications related to surgery. Conclusion: AC should be considered in the differential diagnosis of lesions causing myelopathy and/or a radicular pain syndrome. Microsurgical resection or generous fenestration in cysts effectively ameliorated patients’ symptomatology.
Spontaneous intracerebral hemorrhage treated by neuroendoscopy – Technical note
Authors: Romero Flávio Ramalho , Zanini Marco Antôno , Ducatti Luiz Gustavo , Gabarra Roberto Colichio 
Published: January 2018

AbstractSpontaneous intracerebral hemorrhage (SICH) is responsible for 10%-15% of the acute stroke. Hematoma or the occlusion of cerebrospinal fluid (CSF) flow by ventricular clotting can result in obstructive hydrocephalus, increasing intracranial pressure, which needs urgent decompression. We report our results of management of spontaneous deep cerebral hematoma by endoscopic approach.
Brainstem cavernous malformation
Authors: Estramiana Ariel Roberto , Pinto de Santana Diana Lara , Figueiredo Eberval Gadelha , Teixeira Manoel Jacobsen 
Published: January 2018

AbstractCavernous malformation (CM) of the central nervous system (CNS) are acquired or developmental vascular malformations that represent the 5% to 15% of all vascular malformations of the CNS. Eighty to ninety percent of CM are supratentorial, 15% infratentorial, and 5% occur in the spinal cord. The subset of brainstem malformation presents as a very difficult paradigm for treating clinicians. The widespread use of magnetic resonance imaging (MRI) has increased the recognition of this disease. Clinical presentation, pathophysiology and treatment are discussed in this article.
Avaliação clínica da descompressão medular anterior em portadores de mielopatia cervical
Authors: Rezende Rodrigo , Junqueira de Faria Fernando , Cardoso Igor Machado , Batista Junior José Lucas , Júnior Chárbel Jacob 
Published: January 2018

Resumo
Objetivo: Avaliação clínica neurológica pré e pós-operatória de pacientes portadores de mielopatia cervical submetidos à descompressão medular por via anterior. Métodos: Utilização das escalas de Nurick e de JOA (Japanese Orthopaedic Association), adaptadas para a população brasileira, no período pré e pós-operatório, como método de mensuração do grau de comprometimento neurológico, aplicando-se o teste t de Student e o teste de Wilcoxon, com significância p < 0,05. Resultados: Participaram do estudo 30 pacientes. A média do JOA no pré-operatório foi de 9,5 (DP = 2,8) e no pós-operatório, de 13,5 (DP = 3,0). O valor médio de Nurick foi de 3,7 (DP = 1,2) e 2,1 (DP = 1,2) no pré e pós-operatório, respectivamente. Conclusão: A descompressão medular via anterior melhorou em cerca de 40% o quadro neurológico inicial, portanto pode ser considerada uma real opção de tratamento para pacientes portadores de mielopatia cervical.
Realidade virtual e estereoscopia no ensino da neuroanatomia e neurocirurgia
Authors: Tostes Ferreira Mauro Augusto , Silva Gusmão Sebastião Nataniel , Spetzler Robert Frederich 
Published: January 2018

Resumo
Objetivo: Por motivos diversos, o ensino da neuroanatomia durante a graduação médica e na residência de neurocirurgia é deficitário. Apresentamos a realidade virtual e a estereoscopia como eventuais métodos complementares de ensino à neuroanatomia e neurocirurgia. Método: Diversa gama de conteúdo digital interativo e estereoscópico foi produzida utilizando esterogramas de dissecações anatômicas. Resultados: A realidade virtual tenta melhor elaborar o ensino da neuroanatomia e neurocirurgia. Embora o trabalho verse sobre neuroanatomia e neurocirurgia, esses recursos podem ser empregados em qualquer área médica. Conteúdo anatômico de excelência foi adquirido e armazenado de modo que pôde ser manipulado por programa de realidade virtual e estereoscopia. Conclusão: A realidade virtual e a estereoscopia são ferramentas úteis no ensino e na aprendizagem da neuroanatomia e da neurocirurgia.
Accuracy of two different criteria for neurophysiological intraoperative monitoring (NIOM) in spine/spinal cord surgeries
Authors: Dominici Michele , Chaloult Erik , Ventura Fabrício Dutra , Comerlato Enio Alberto 
Published: January 2018

Abstract
Objective: Our objective was to compeer the accuracy between two warning criteria during the intraoperative neurophysiologic monitorization for spine/spinal cord surgery. Method: We used two different warning criteria to detect neurological damage. The first criterion was the amplitude reduction of the somatossensory-evoked potentials (SEP) or motor-evoked potentials (MEP) greater than 50% at least in one limb and the second criterion was the complete loss of one of the same potentials. These results were compared with the neurological examination and the sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) was calculated for each criterion. Results: The sensitivity, specificity, PLR and NLR were respectively for criterion 1 and 2 (0,92/0,58; 0,96/0,99; 24/46 and 0,09/0,57). Conclusion: The first criterion suggests a better sensitivity and accuracy as a warning criterion to avoid central neurological damage.
Cateter ventriculoperitoneal migrado para o escroto através de hérnia inguinal – Relato de caso
Authors: da Cunha Eduardo Procaci , Moreira Sérgio , Gomes Mário , Mesquita Isabel , Simões Vítor , Carvalho Ernesto de 
Published: January 2018

ResumoA derivação ventriculoperitoneal é atualmente o método mais utilizado no tratamento da hidrocefalia comunicante. As complicações mais comuns são a disfunção do shunt e infecções. Este relato de caso tem como objetivo apresentar um doente com idas recorrentes ao serviço de urgência por agitação psicomotora e dor abdominal, e cujo cateter distal previamente desconectado encontrava-se alojado no interior do saco escrotal através de hérnia inguinoescrotal. A formação de hérnia inguinal com migração de cateter é um evento raro no adulto, sendo mais comum na criança, possivelmente pela maior taxa de patência do processo vaginal e aumento da pressão intra-abdominal. No momento em que este artigo foi redigido, não foi encontrado caso semelhante na literatura.
Erythropoietin in vasospasm. From bench to bedside?
Authors: Welling Leonardo Christiaan , Welling Mariana Schumacher , Figueiredo Eberval Gadelha , Teixeira Manoel Jacobsen 
Published: January 2018

AbstractAneurysmal subarachnoid haemorrhage is one of the most deleterious acute neurological diseases. The cerebral ischemia secondary to arterial vasospasm occurring after aneurysmal subarachnoid haemorrhage is still responsible for the considerable morbidity and mortality in these patients. Besides the knowledge of basic mechanisms of cerebral vasoespasm following aneurysmal subarachnoid haemorrhage, the prophylaxis and treatment of this pathology however still remain suboptimal. There is some evidence that acute erythropoietin treatment may reduce the severity of cerebral vasospasm and eventually improve outcome in aneurysmal subarachnoid haemorrhage patients. There are underlying mechanisms extend far beyond erythropoiesis: like enhancing neurogenesis, decreasing inflammation and apoptosis inhibition. In this review the authors describe many of the biologic effects, especially experimental studies and clinical studies that reported why the erythropoietin could be beneficial to patients with aneurysmal subarachnoid haemorrhage.
Epidemiology of traumatic spinal injuries in Brazil: systematic review
Authors: Botelho Ricardo Vieira , Gianini Albuquerque Luciana Dini , Junior Rafael Bastianello , Arantes Júnior Aluízio Augusto 
Published: January 2018

AbstractPrevention remains the most effective way to reduce the burden of spinal injuries (SI). Estimating the incidence and causes of SI is essential for the development of prevention programs. To reveal the current state of Brazilian ST epidemiology. To evaluate the current state of Brazilian SI epidemiology, we performed an electronic search using the Lilacs database (Latin American and Caribbean Health Sciences Literature). Fifteen papers and one unsubmitted ongoing study (BH project) reported the epidemiologic status of ST in Brazil. The mean age of SI patients was 34,75 years, and 84% of patients were male. The most commonly affected segment was the cervical spine (36.65%). The incidence ranged from 16 to 26 patients per million per year (average 21 per million per year). The average rate of complete spinal cord injury among five papers was 34%. The average mortality in four papers was 11.58%. Analyzing published national epidemiological data enables the estimation of the current state of Brazilian SI epidemiology.
Infarto cerebral hemisférico: algoritmo de tratamento baseado em evidência
Authors: Campos Wuilker Knoner , Damian Guasti José Antônio 
Published: January 2018

ResumoO infarto cerebral hemisférico maligno tem mortalidade de 80%, apesar do tratamento conservador. Ele representa infarto de mais de 50% do território da artéria cerebral média (ACM), entretanto, nem todos os pacientes irão desenvolver o curso maligno. O objetivo desta revisão foi encontrar os fatores preditivos do curso maligno do edema cerebral maligno e, a partir desses fatores, propor um algoritmo de tratamento e tomadas de decisões para o infarto cerebral hemisférico. Os preditores foram pesquisados em artigos no PubMed. Com base nos preditores encontrados com valor estatístico significativo, estruturou-se um algoritmo de gerenciamento para o infarto cerebral hemisférico. Os fatores preditivos de curso maligno foram: NIHSS > 15 hemisfério dominante e > 20 não dominante; oclusão da artéria carótida interna (ACI) ipsilateral à malformação do círculo de Willis; circulação colateral deficiente; tomografia computadorizada (TC) hipodensidade > 50% e ressonância magnética (RM) difusão > 145 cm3 do território da ACM; outro território vascular envolvido; perda da autorregulação; potencial evocado auditivo patológico; pressão intracraniana (PIC) > 35 mmHg e valores de pico de aminoácidos excitatórios medidos na microdiálise. Entretanto, esses dois últimos fatores aparecem apenas depois que o paciente está herniado. Os trials europeus definiram nível de evidência 1 para craniectomia descompressiva. Craniectomia descompressiva é o tratamento de primeira escolha para os pacientes < 60 anos com curso maligno do infarto hemisférico < 48h. Os fatores preditivos são importantes ferramentas para tomada de decisão quanto à indicação cirúrgica precoce.
Psicocirurgia para tratamento de transtorno obsessivo-compulsivo
Authors: Da Róz Leila Maria , Carvalhal Ribas Eduardo Santamaria , Ballester Gerson , Figueiredo Eberval Gadelha , Teixeira Manoel Jacobsen 
Published: January 2018

ResumoO transtorno obsessivo-compulsivo (TOC) é uma patologia incapacitante tanto na esfera social como na ocupacional. Está associado a uma morbidade bastante alta quando comparado a outras condições psiquiátricas e estima-se atualmente uma prevalência de 2% a 3% na população. Alguns estudos sugerem uma provável relação com uma disfunção do córtex frontal e do cíngulo, envolvendo o circuito de Papez. Esse circuito parece mediar os sintomas ansiosos, visto que lesões cirúrgicas dessas áreas afetam a ansiedade geralmente associada ao TOC. A neurocirurgia ablativa para o tratamento de distúrbios psiquiátricos foi muito utilizada até o desenvolvimento de psicofármacos efetivos. Recentemente, com os avanços técnicos do procedimento cirúrgico, auxiliado pelo conhecimento neurofisiológico, a psicocirurgia tornou-se mais precisa e segura. Porém, sua indicação se restringe como uma alternativa ao tratamento de pacientes com TOC refratário à terapia comportamental e/ ou medicamentosa.
Espondilolistese traumática do áxis – Experiência em 41 casos
Authors: Faleiro Rodrigo Moreira , Godoy Newton José , Campos Rafael Cardoso , Ávila Geraldo 
Published: January 2018

Resumo
Objetivo: Levantamento epidemiológico retrospectivo da prevalência de espondilolistese traumática do áxis no período de cinco anos em HJXXIII – FHEMIG. Métodos: Foram avaliados 1.136 casos de traumatismo raquimedular admitidos no período em HJXXIII – FHEMIG. Resultados: 762 (67%) correspondiam a trauma em segmento cervical, 41 casos (5,3%) a ETA. Predomínio em adultos jovens do sexo masculino. A etiologia mais comum foi acidente automobilístico. Segundo classificação de Levine, o tipo de fratura mais comum foi o tipo I (70,8%), seguido pelo tipo II (16%), tipo IIa (9,6%) e tipo III (3,2%). Conclusão: A espondilolistese traumática do áxis geralmente é uma fratura estável, sendo satisfatoriamente tratada por meio de órtese externa. Os déficits neurológicos são incomuns e, quando presentes, geralmente são decorrentes de lesões associadas.
Usage characteristics and adverse event rates ​of the direct puncture and pull techniques for percutaneous endoscopic gastrostomy in patients with malignant tumors of the upper aerodigestive tract
Authors: Teich Niels , Selig Lars , Liese Susanne , Schiefke Franziska , Hemprich Alexander , Mössner Joachim , Schiefke Ingolf 
Published: January 2018

Abstract
Background and study aims Patients with malignant tumors of the upper gastrointestinal tract are at risk of weight loss. Early supportive nutrition therapy is therefore recommended and usually requires placement of a percutaneous endoscopic gastrostomy (PEG). The aim of this study was to compare adverse events and usage characteristics of the direct puncture technique with those of the traditional pull technique when used in patients with endoscopically passable tumors. The primary endpoint was the rate of inflammatory adverse events (AEs) at the gastrostomy fistula. The secondary endpoint was the long-term rate of puncture-site metastases.
Patients and methods One hundred twenty patients (median age 56; IQR 36, 86 years) were randomized and treated per protocol in this prospective open randomized single-center study. Follow-ups were conducted on the third and seventh post-interventional days, after 1, 3 and 6 months and the last follow-up 5 years after intervention.
Results Within the short-term follow-up period of 6 months after PEG placement, AEs were noted in 47 patients (39.2 %). These included 22 inflammations and 16 device dislocations and were mainly found in the puncture group (33 vs. 14 in the pull group) with a significantly increased incidence in the first month after PEG insertion (P = 0.001). Evaluation of the 5-year data did not reveal any significant differences. The gastrostomy tube was used in 101 patients (84.2 %) (range 18 days to 5 years).
Conclusions Our results favor the pull technique for patients with endoscopically passable tumors of the upper gastrointestinal tract due to less short-term adverse events. Both systems contributed equally to secure long-term use.
Risk of colonic diverticular rebleeding according to endoscopic appearance
Authors: Kawanishi Koki , Kato Jun , Kakimoto Tetsuhiro , Hara Takeshi , Yoshida Takeichi , Ida Yoshiyuki , Maekita Takao , Iguchi Mikitaka , Kitano Masayuki 
Published: January 2018

Abstract
Background and study aims Re-commencement of bleeding (rebleeding) of colonic diverticula after endoscopic hemostasis is a clinical problem. This study aimed to examine whether endoscopic visibility of colonic diverticular bleeding affects the risk of rebleeding after endoscopic hemostasis.
Patients and methods We performed a retrospective review of endoscopic images and medical charts of patients with colonic diverticular bleeding who underwent endoscopic hemostasis. Endoscopic visibility was classified into two types according to visibility of the source of bleeding; source invisibility due to bleeding or attached hematin (type 1), or endoscopically visible responsive vessels (type 2). Rebleeding rates within one year after initial hemostasis were examined.
Results Of 93 patients with successful endoscopic hemostasis, 38 (41 %) showed type 1 visibility, while the remaining presented type 2. All patients received hemostasis with clipping, rebleeding developed in 20 patients (22 %). Type 1 visibility was more likely to be observed in patients with rebleeding (65 % vs. 34 %, P = 0.013). Multivariate analysis revealed that after endoscopic hemostasis, type 1 visibility (invisible source) was the only independent risk factor for colonic diverticular rebleeding (odds ratio, 3.05; 95 % confidence interval, 1.03 – 9.59, P = 0.044). Kaplan-Meier curve showed the cumulative incidence of rebleeding was significantly higher in patients with type 1 visibility than those with type 2 visibility (P = 0.0033, log-rank test)
Conclusion Hemostasis by clipping for colonic diverticular bleeding without definite observation of the source of bleeding may not be sufficiently effective. Other hemostatic methods, including band ligation, should be considered when the source of bleeding is unclear.
Sign-creation in the Seattle DeafBlind community
Authors: Edwards Terra 
Published: January 2018

Abstract
This article examines the social and interactional foundations of sign-creation among DeafBlind people in Seattle, Washington. Linguists studying signed languages have proposed models of sign-creation that involve the selection of an iconic gestural representation of the referent which is subjected to grammatical constraints and is thereby incorporated into the linguistic system. Drawing on 18 months of ethnographic fieldwork and more than 190 hours of video recordings of interaction and language use, I argue that a key interactional mechanism driving processes of sign-creation among DeafBlind people in Seattle is deictic integration. Deictic integration restricts the range of contextual values that the grammar can retrieve by coordinating systems of reference with patterns in activity. This process brings language into alignment with the world as it is perceived by the users of that language, making a range of potentially iconic relations available for selection in the creation of new signs.
The Spanish component in Lingua Franca
Authors: Operstein Natalie 
Published: January 2018

AbstractThe best-documented variety of Lingua Franca (lf), the one spoken in Algiers just before the French colonization of Algeria, comprises three main Romance lexical components; in order of numerical importance, these are Italian, Spanish and French. While it is agreed that the French component is the most recent one, the relationship between the Spanish and the Italian components has given rise to competing diachronic interpretations. This paper examines probable Spanish contributions to Algerinelfin the lexicon, copula and pronominal possession. It contributes to our understanding of the origins and evolution of Algerinelf, as revealed through language-internal analysis of its lexical and structural components.
Language contact in the Philippines
Authors: Gonzales Wilkinson Daniel Wong 
Published: January 2018

Abstract
This article narrates the sociohistory of the Philippines through the lens of a Sinitic minority group – the Chinese Filipinos. It provides a systematic account of the history, language policies, and educational policies in six major eras, beginning from the precolonial period until the Fifth Republic (960 – present). Concurrently, it presents a diachronic narrative on the different linguistic varieties utilized by the ethnic minority, such as English, Hokkien, Tagalog, and Philippine Hybrid Hokkien (PHH). Following an exposition on how these varieties were introduced to the ecology is a discussion focused on contact that highlights potential theories as to how Philippine contact varieties like PHH emerged. How this account contributes to the overall language ecology forms the conclusion. Overall, this article delineates the socio-historical sources that intrinsically play a significant role in the (re)description of Philippine contact varieties. In its breadth, this article goes beyond providing second-hand information, and presents ideas that can be crucial for understanding how Philippine contact languages work.
Primary Cutaneous Spindle Cell Squamous Carcinoma Expressing Smooth Muscle Actin: Diagnostic Pitfalls
Authors: Ahmad Abdullahi , Chung Hye Jin , Bhawan Jag 
Published: January 2018

Abstract:
Alpha smooth muscle actin (SMA) belongs to the actin proteins. It is a known immunohistochemical marker for tumors of mesenchymal origin. There have been reports of expression of SMA in certain epithelial malignancies in the head and neck and genital regions. In this study, the authors report a primary cutaneous spindle cell squamous carcinoma expressing SMA. Both high- and low-molecular-weight keratins and p63 were positive, and S100 protein, SOX10, MART-1/Melan-A, and muscle-specific actin stains were negative. This case highlights that an epithelial tumor could express a mesenchymal marker, thereby making the diagnosis problematic.