bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does maternal education moderate the relationship between adolescent cannabis use and mental health in early adulthood?
Authors: Sawyer Gemma , Howe Laura D. , Hickman Matthew , Zammit Stanley , Hines Lindsey A. 
Published: September 2024

AbstractIntroductionSocioeconomic disadvantage has been associated with cannabis use and poor mental health. It is therefore hypothesised that lower maternal education, a proxy for socioeconomic disadvantage, may increase the risk of cannabis‐related mental health and substance use consequences.MethodsA total of 5099 participants from the Avon Longitudinal Study of Parents and Children reported cannabis use via questionnaires at 16 or 18. Logistic regression was used to examine the relationship between any and regular (weekly or more) adolescent cannabis use with depression, anxiety, psychotic experiences, and problematic cannabis use at age 24. Maternal education was included as an effect modifier. Missing data were addressed through multiple imputation using chained equations.ResultsIn total, 36.5% of participants reported adolescent cannabis use and, of these, 14% reported regular use. Adolescent cannabis use was associated with an increased likelihood of anxiety and problematic cannabis use; however, there was little evidence of moderation by maternal education. Regular cannabis use was associated with an increased likelihood of problematic cannabis use, with little evidence of moderation by maternal education. There was weak evidence that the association between regular cannabis use and depression (interaction p‐value = 0.024) and anxiety (interaction p‐value = 0.056) was stronger in people with high maternal education.Discussion and ConclusionsAdolescent cannabis use is associated with increased risk of anxiety and cannabis use disorder, but there was insufficient evidence that childhood socioeconomic position (proxied by maternal education) modifies this relationship. Improved public health messages for all adolescents about these risks may be warranted.
Acquired motor speech disorders in childhood epilepsy
Authors: Eyre Michael , Rose Steve , Gwynn Rachel , Pressler Ronit M. , Clark Maria 
Published: September 2024

AbstractAimTo evaluate a group of children with epilepsy and motor speech regression, with the aim of characterizing their speech disorders, electrographic features, and outcomes.MethodChildren referred to a tertiary developmental epilepsy clinic with epilepsy and motor speech regression were identified retrospectively. A clinical history was taken, and longitudinal speech and cognitive data were recorded. Speech samples were scored for severity and speech features. Seizure frequency and epileptiform discharges in the interictal electroencephalogram were analysed.ResultsEighteen children (10 female) were evaluated, including seven with Landau–Kleffner syndrome and six with Rasmussen syndrome. Speech regression occurred at a mean age of 5 years (SD = 2 years 6 months), which was concurrent with seizure onset or peak seizure burden in eight children. Speech features included dysarthria (n = 13), phonological errors (n = 7), and dyspraxia (n = 6). Electrographic abnormalities occurred most frequently in the left centrotemporal and right frontal regions. Among children who were followed up, intelligibility of speech was affected in 13 at baseline and seven at follow‐up (p = 0.03). Expressive language standardized scores increased from a mean (SD) of 50.0 (11.3) to 91.4 (27.8) in children with Landau–Kleffner syndrome (mean change = 41.4, 95% confidence interval [CI] 0.04–82.8, p = 0.0498) and decreased from 75.2 (15.3) to 59.0 (9.8) in children with Rasmussen syndrome (mean change −16.2, 95% CI −9.0 to −23.4, p = 0.002) over the follow‐up.InterpretationMotor speech disorders in epilepsy were severe, multifarious, and often fluctuated with seizure burden. Symptoms typically improved, especially in children with Landau–Kleffner syndrome, but rarely fully resolved.
Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy
Authors: Dubey Vaibhav , Tanday Neil , Irwin Nigel , Tarasov Andrei I. , Flatt Peter R. , Moffett R. Charlotte 
Published: September 2024

AbstractBackgroundPancreatic islet β‐cell mass expands during pregnancy, but underlying mechanisms are not fully understood. This study examines the impact of pregnancy and cafeteria diet on islet morphology, associated cellular proliferation/apoptosis rates as well as β‐cell lineage.MethodsNon‐pregnant and pregnant Ins1Cre/+;Rosa26‐eYFP transgenic mice were maintained on either normal or high‐fat cafeteria diet, with pancreatic tissue obtained at 18 days gestation. Immunohistochemical changes in islet morphology, β‐/α‐cell proliferation and apoptosis, as well as islet cell identity, neogenesis and ductal cell transdifferentiation were assessed.ResultsPregnant normal diet mice displayed an increase in body weight and glycaemia. Cafeteria feeding attenuated this weight gain while causing overt hyperglycaemia. Pregnant mice maintained on a normal diet exhibited typical expansion in islet and β‐cell area, owing to increased β‐cell proliferation and survival as well as ductal to β‐cell transdifferentiation and β‐cell neogenesis, alongside decreased β‐cell dedifferentiation. Such pregnancy‐induced islet adaptations were severely restricted by cafeteria diet. Accordingly, islets from these mice displayed high levels of β‐cell apoptosis and dedifferentiation, together with diminished β‐cell proliferation and lack of pregnancy‐induced β‐cell neogenesis and transdifferentiation, entirely opposing islet cell modifications observed in pregnant mice maintained on a normal diet.ConclusionAugmentation of β‐cell mass during gestation arises through various mechanisms that include proliferation and survival of existing β‐cells, transdifferentiation of ductal cells as well as β‐cell neogenesis. Remarkably, cafeteria feeding almost entirely annuls pregnancy‐induced islet adaptations, which may contribute to the development of gestational diabetes in the setting of dietary provoked metabolic stress.
The Exteriority of Thinking: Hegel and Heidegger
Authors: Khurana Thomas 
Published: September 2024

AbstractIn The Culmination, Robert Pippin offers a stunning reassessment of the achievements of absolute idealism. Having developed some of the most persuasive defenses of Hegel's absolute idealism to date, Pippin now argues that Heidegger's trenchant critique of Hegel has revealed a dogmatism at the very heart of absolute idealism: an unwarranted identification of what is with what is discursively knowable. This dogmatic identification leads to a distorted understanding of the meaning of Being, a reifying account of beings, and a neglect of our own finitude. In this article, I defend Hegel against these charges. The upshot of this discussion is twofold. Rather than evading the question of the exteriority of being, I argue, Hegel in fact aims to reveal that this exteriority is internal to thinking itself. And rather than identifying the meaning of being with discursive knowability, Hegel shows that the meaning of being resides in a form of freedom that goes beyond the self‐transparency of knowing.
Poststroke seizures and epilepsy increase the risk of dementia among stroke survivors: A population‐based study
Authors: Sung Kuan‐Lin , Kuo Miao‐Jen , Yang Hsin‐Yi , Tsai Ching‐Fang , Sung Sheng‐Feng 
Published: September 2024

AbstractObjectiveWith global aging, the occurrence of stroke and associated outcomes like dementia are on the rise. Seizures and epilepsy are common poststroke complications and have a strong connection to subsequent dementia. This study examines the relationship between poststroke seizures (PSS) or poststroke epilepsy (PSE) and dementia using a national health care database.MethodsWe conducted a retrospective study using data from the Taiwan National Health Insurance Research Database from 2009 to 2020. We identified acute stroke patients from 2010 to 2015, excluding those with pre‐existing neurological conditions. Based on age, sex, stroke severity level, and the year of index stroke, patients with PSS or PSE were matched to those without. The main outcome was incident dementia.ResultsThis study included 62 968 patients with an average age of 63 years, with males accounting for 62.9%. Of them, 60.3% had ischemic strokes, and 39.7% had hemorrhagic strokes. After an average follow‐up period of 5.2 years, dementia developed in 15.9% of patients who had PSS or PSE, as opposed to 8.4% of those without these conditions. A time‐dependent Fine and Gray competing risk analysis showed that PSS and PSE were significantly associated with dementia across all stroke types. Subgroup analyses revealed significantly increased risk of dementia across all age groups (<50, 50–64, and ≥65 years), sexes, and various stroke severity levels. The link between PSS or PSE and dementia was particularly pronounced in men, with a less distinct correlation in women.SignificanceThe risk of incident dementia was higher in patients with PSS or PSE. The potential for therapeutic interventions for seizures and epilepsy to reduce poststroke dementia underscores the importance of seizure screening and treatment in stroke survivors.
Explaining the penetrating role of technology in online foreign language learning achievement
Authors: Huang Fangwei , Zhang Haijing 
Published: September 2024

AbstractThis study aims to integrate the technology acceptance model, classroom environment theory, and positive psychology theory to explore the relationships among learners' technology acceptance (TA), perceived online classroom environment (POCE), emotional states (enjoyment, anxiety, boredom, and burnout), and academic achievement in online classes. Six hundred and sixty‐two university students learning Chinese as a foreign language participated in the survey and completed the reading test. The results of partial least square‐structural equation modeling reveal that TA influences reading achievement directly and indirectly through anxiety (with the reversed mediating effect) and enjoyment, and the online classroom environment mediated the relationship between TA and learning emotions (except anxiety). These findings suggest that technology factors may shape the affordance of online classrooms and penetrate environmental and emotional variables to impact FL learning outcomes. Multigroup analysis with different self‐online learning time underscores that enjoyment and anxiety differ in two different effect paths (POCE‐enjoyment) and (TA‐anxiety), implying enjoyment may be more environment‐related while anxiety may be more technology‐related in the online foreign language classroom. This study provides both theoretical and pedagogical implications.
Males miss and females forgo: Auditory masking from vessel noise impairs foraging efficiency and success in killer whales
Authors: Tennessen Jennifer B. , Holt Marla M. , Wright Brianna M. , Hanson M. Bradley , Emmons Candice K. , Giles Deborah A. , Hogan Jeffrey T. , Thornton Sheila J. , Deecke Volker B. 
Published: September 2024

AbstractUnderstanding how the environment mediates an organism's ability to meet basic survival requirements is a fundamental goal of ecology. Vessel noise is a global threat to marine ecosystems and is increasing in intensity and spatiotemporal extent due to growth in shipping coupled with physical changes to ocean soundscapes from ocean warming and acidification. Odontocetes rely on biosonar to forage, yet determining the consequences of vessel noise on foraging has been limited by the challenges of observing underwater foraging outcomes and measuring noise levels received by individuals. To address these challenges, we leveraged a unique acoustic and movement dataset from 25 animal‐borne biologging tags temporarily attached to individuals from two populations of fish‐eating killer whales (Orcinus orca) in highly transited coastal waters to (1) test for the effects of vessel noise on foraging behaviors—searching (slow‐click echolocation), pursuit (buzzes), and capture and (2) investigate the mechanism of interference. For every 1 dB increase in maximum noise level, there was a 4% increase in the odds of searching for prey by both sexes, a 58% decrease in the odds of pursuit by females and a 12.5% decrease in the odds of prey capture by both sexes. Moreover, all but one deep (≥75 m) foraging attempt with noise ≥110 dB re 1 μPa (15–45 kHz band; n = 6 dives by n = 4 whales) resulted in failed prey capture. These responses are consistent with an auditory masking mechanism. Our findings demonstrate the effects of vessel noise across multiple phases of odontocete foraging, underscoring the importance of managing anthropogenic inputs into soundscapes to achieve conservation objectives for acoustically sensitive species. While the timescales for recovering depleted prey species may span decades, these findings suggest that complementary actions to reduce ocean noise in the short term offer a critical pathway for recovering odontocete foraging opportunities.
YouTubing Remittances, Revealing (Dis)connectedness: Copresence as Fiction, Ideal and Heuristic on the YouTube Channel of Western Union
Authors: Boccagni Paolo , Marconi Valentina , Brodesco Alberto 
Published: September 2024

ABSTRACTSending and receiving remittances is central to the negotiation of transnational family life, and to nourishing a sense of copresence among physically distant parties. Although the lived experience of this transaction has a very intimate and personal basis, it is also subject to increasing visual and public representation, as a part of the working of dedicated migration industries. Based on an in‐depth exploration of the advertising materials on the YouTube channel of Western Union (WU), we analyse how money circulation is made visible, emplaced in migrant life circumstances and co‐produced through visual narratives that illuminate the micro‐foundations of copresence and its structural limitations. While following the rationale of a commercial product, and despite their idealized contents, WU's stories are revealing about the relational affordances for virtual copresence, its shortcomings and the social embeddedness of remittances in family life.
Factors Associated With Decision to Treat or Not to Treat Helicobacter pylori Infection in Children: Data From the EuroPedHp Registry
Authors: Le Thi Thu Giang , Werkstetter Katharina , Kotilea Kallirroi , Bontems Patrick , Cabral José , Cilleruelo Maria Luz , Kori Michal , Barrio Josefa , Homan Matjaž , Kalach Nicolas , Lima Rosa , Tavares Marta , Urruzuno Pedro , Misak Zrinjka , Urbonas Vaidotas , Koletzko Sibylle ,   for the Helicobacter pylori Special Interest Group of ESPGHAN
Published: September 2024

ABSTRACTBackgroundEuropean and North‐American guidelines on management of H. pylori infection in children provide the option not to treat even if the infection is endoscopically confirmed. We used data from the EuroPedHp Registry to identify factors associated with therapy decisions.MethodsWe included treatment‐naïve patients reported between 2017 and 2020 from 30 centers in 17 European countries. Multivariable logistic regression identified factors including comorbidities within and outside the gastrointestinal (GI) tract influencing the decision for or against therapy.ResultsOf 1165 patients (52% females, median age 12.8), 28% (321/1165) reported any alarm symptom, 26% (307/1165) comorbidities, and 16% (192/1165) did not receive eradication treatment. Therapy was initiated less often in children having any GI comorbidity (57%, n = 181), particularly in those with eosinophilic esophagitis (60%, n = 35), inflammatory bowel disease (54%, n = 28), and celiac disease (43%, n = 58), compared to those with non‐GI (86%, n = 126) or no comorbidity (89%, n = 858), despite similar frequencies of alarm and non‐alarm symptoms, ulcers, erosions, and nodular gastritis. Patients with GI and without comorbidities remained more likely untreated in high versus low H. pylori prevalence countries (p < 0.0001). In children without comorbidities, factors favoring therapy included older age, being overweight, having symptoms, erosions, antral nodularity, and available antibiotic susceptibility results.ConclusionIn this cohort, H. pylori‐infected children with GI comorbidities compared to no comorbidity showed 75% reduced chance of receiving eradication therapy. We found no evidence supporting different management strategies in infected patients with GI comorbidities compared to all pediatric patients with endoscopically proven H. pylori infection.
Recovery of bioactive compounds from oil palm waste using green extraction techniques and its applications
Authors: Chew Sook Chin , How Yu Hsuan , Hasan Zafarizal Aldrin Bin Azizul , Chu Chee Chin 
Published: September 2024

SummaryOil palm (Elaeis guineensis) is a major oil crop that significantly contributes to the Indonesia's and Malaysia's economic growth. However, oil palm processing for oil extraction generates substantial waste, such as palm kernel cake, palm‐pressed fibre, oil palm empty fruit bunches and palm oil mill effluent, which pose noticeable environmental challenges. This review explores green extraction techniques for palm waste processing, which include microwave‐assisted extraction, deep eutectic solvents, ultrasound‐assisted extraction, supercritical fluid extraction, enzyme‐assisted extraction and subcritical water extraction. The potential for industry scaling, mechanisms, applications and challenges of each technique used for oil palm waste are discussed. Microwave‐assisted extraction, ultrasound‐assisted extraction and supercritical fluid extraction are particularly promising for large‐scale production, while deep eutectic solvents paired with ultrasound‐assisted extraction show the potential to improve extraction efficiency. This review also reveals that green extraction techniques are sustainable alternative to conventional techniques by effectively recovering valuable compounds from waste with reduced environmental impact. Additionally, the diverse applications of bioactive compounds (vitamin E, phytosterols, phenolics, polyphenols and flavonoids) extracted from oil palm waste in food, pharmaceutical, cosmetic and other industries are also presented. Valuable components such as cellulose, dietary fibres and bioactive peptides derived from the waste can be applied in food coatings, high‐protein products and drug delivery systems. Biosorbents, biofuels and biodegradable products derived from the waste would also provide environmental benefits. Future research should focus on optimising the green extraction techniques for industrial use to promote responsible production and circular waste management to foster health and environmental safety.
Chemical composition and sensory profile of Spirogyra neglecta (Hassall) Kützing
Authors: Sriwattana Sujinda , Chokumnoyporn Napapan , Brennan Charles , Prinyawiwatkul Witoon 
Published: September 2024

SummaryThe proximate composition, selected amino acid composition, and chemical constituents of Spirogyra neglecta (Hassall) Kützing, a freshwater algae collected from Phrae province, Thailand was investigated. It was found to be a good source of protein (29.42% dry wt. basis) and fibre (6.70% dry wt. basis). The total amino acid content was 2611.85 mg/100 g edible. The chemical constituents were characterised by GC–MS, which demonstrated that it contained phytol (62.10%), ethyl 5,8,11,14,17‐icosapentaenoate (8.55%) among others. Based on its chemical composition results, it could serve as a potential ingredient with high nutritional values in the food and nutraceutical industry. Furthermore, the descriptive sensory profile consisting of 17 descriptors, namely, green colour, glossy, filamentous, aroma (algae, grassy, fishy, and earthy), flavour (algae, grassy, fishy, and earthy), sweet, bitter, and texture (fibrousness and softness), mouthfeel (entire mouth‐coating), and aftertaste (astringent), were successfully developed to allow characterisation of the sensory quality of this algae.
Experiences of Mental Health Nurses in Providing Care to Patients Receiving Electroconvulsive Therapy in South Korea
Authors: Ahn Suyoun , Shin Soyoung , Joung Jaewon 
Published: September 2024

ABSTRACTIn recent years, the demand for electroconvulsive therapy has been increasing in South Korea. However, there are problems due to mental health nurses' lack of understanding about electroconvulsive therapy and the absence of systematic education. This study aimed to explore mental health nurses' experiences of providing care to patients receiving electroconvulsive therapy in South Korea. We used content analysis to analyse the data collected from focus group interviews with 22 mental health nurses working in mental health hospitals. The results revealed four themes and 10 subthemes. More specifically, the results showed that mental health nurses consider themselves helpers in recovery. They pursue the physical and emotional well‐being of patients receiving electroconvulsive therapy and strive to ensure that patients receive electroconvulsive therapy comfortably and safely. However, contentious issues such as concerns about patient dignity and autonomy lead to differing perceptions and attitudes towards electroconvulsive therapy and cause internal conflict during therapeutic interactions. Furthermore, insufficient education on electroconvulsive therapy leads to a lack of knowledge and difficulties in fulfilling the role of an information provider. The shortage of coping measures and support systems for issues such as extensive adverse effects and restricted medication increases the work burden immensely. These findings can serve as foundational data for the development of standardised nursing practices and systematic education for electroconvulsive therapy.
Handling Out‐of‐Sample Areas to Estimate the Unemployment Rate at Local Labour Market Areas in Italy
Authors: Benedetti Roberto , Piersimoni Federica , Pratesi Monica , Salvati Nicola , Suesse Thomas 
Published: September 2024

SummaryUnemployment rate estimates for small areas are used to efficiently support the distribution of services and the allocation of resources, grants and funding. A Fay–Herriot type model is the most used tool to obtain these estimates. Under this approach out‐of‐sample areas require some synthetic estimates. As the geographical context is extremely important for analysing local economies, in this paper, we allow for area random effects to be spatially correlated. The spatial model parameters are estimated by a marginal likelihood method and are used to predict in‐sample as well as out‐of‐sample areas. Extensive simulation experiments are used to assess the impact of the auto‐regression parameter and of the rate of out‐of‐sample areas on the performance of this approach. The paper concludes with an illustrative application on real data from the Italian Labour Force Survey in which the estimation of the unemployment rate in each Local Labour Market Area is addressed.