bluuebunny/crossref_metadata_2025_split huggingface dataset:
Right Here Right Now (RHRN) pilot study: testing a method of near-real-time data collection on the social determinants of health
Authors: Naven Lynn , Inglis Greig , Harris Rachel , Fergie Gillian , Teal Gemma , Phipps Rebecca , Stewart Sally , Kelly Lorna , Hilton Shona , Smith Madeline , McCartney Gerry , Walsh David , Tolan Matthew , Egan James 
Published: July 2017

Background
Informing policy and practice with up-to-date evidence on the social determinants of health is an ongoing challenge. One limitation of traditional approaches is the time-lag between identification of a policy or practice need and availability of results. The Right Here Right Now (RHRN) study piloted a near-real-time data-collection process to investigate whether this gap could be bridged.

Methods
A website was developed to facilitate the issue of questions, data capture and presentation of findings. Respondents were recruited using two distinct methods – a clustered random probability sample, and a quota sample from street stalls. Weekly four-part questions were issued by email, Short Messaging Service (SMS or text) or post. Quantitative data were descriptively summarised, qualitative data thematically analysed, and a summary report circulated two weeks after each question was issued. The pilot spanned 26 weeks.

Results
It proved possible to recruit and retain a panel of respondents providing quantitative and qualitative data on a range of issues. The samples were subject to similar recruitment and response biases as more traditional data-collection approaches. Participants valued the potential to influence change, and stakeholders were enthusiastic about the findings generated, despite reservations about the lack of sample representativeness. Stakeholders acknowledged that decision-making processes are not flexible enough to respond to weekly evidence.

Conclusion
RHRN produced a process for collecting near-real-time data for policy-relevant topics, although obtaining and maintaining representative samples was problematic. Adaptations were identified to inform a more sustainable model of near-real-time data collection and dissemination in the future.
Guía de práctica clínica para la detección temprana, el diagnóstico, el tratamiento y el seguimiento de los defectos refractivos en menores de 18 años
Authors: Sanchez Vanegas Guillermo , Buitrago García Diana Carolina , Moreno Carlos , Segura María Margarita , Fernández Jaramillo Juliana , Solano Franco Adriana Andrea , Mayorga Corredor Myriam Teresa , González Luz Esperanza , Giraldo Olga Lucía , Jácome Álvaro , Rodríguez Hernández Andrea Esperanza , Castro Carlos Alberto , Sánchez Ada María , Lamus Ana Milena , Fuentes Wilson Enrique , Medina Roger David , Godoy Casabuenas Natalia , Angulo Sara 
Published: July 2017

Objetivo: generar recomendaciones para la prevención, detección temprana, diagnóstico, tratamiento y seguimiento de defectos refractivos en menores de 18 años, con el fin de apoyar al personal de salud responsable de la atención a estos pacientes en los diferentes servicios.
Materiales y métodos: Un grupo interdisciplinario de profesionales y representantes de pacientes definieron el alcance, objetivos, preguntas y desenlaces de la guía. Se realizó una búsqueda de literatura de revisiones sistemáticas, metaanálisis, ensayos clínicos, estudios de cohorte, estudios de casos y controles en las bases de datos MEDLINE, EMBASE y CENTRAL publicados hasta el 2014. Se evaluó la calidad metodológica de los artículos seleccionados. Posteriormente se elaboraron las tablas de evidencia por medio del software GRADEpro® 3.6 y se generaron las recomendaciones bajo la metodología GRADE.
Resultados:
Se formularon recomendaciones para la detección temprana, diagnóstico,
tratamiento y seguimiento de los defectos refractivos en menores de 18 años. Adicionalmente
se presentan varias preguntas generales de contexto que no generan recomendaciones.
Guía de práctica clínica para la prevención, la detección temprana, el diagnostico, el tratamiento y el seguimiento de la ambliopía en menores de 18 años
Authors: Sanchez Vanegas Guillermo , Buitrago García Diana Carolina , Buitrago García Diana Carolina , Moreno Carlos , Segura María Margarita , Fernández Jaramillo Juliana , Solano Franco Adriana Andrea , Mayorga Corredor Myriam Teresa , González Luz Esperanza , Giraldo Olga Lucía , Jácome Álvaro , Rodríguez Hernández Andrea Esperanza , Castro Carlos Alberto , Sánchez Ada María , Lamus Ana Milena , Fuentes Wilson Enrique , Medina Roger David , Godoy Casabuenas Natalia , Angulo Sara 
Published: July 2017

Objetivo: Generar recomendaciones para la prevención, detección temprana, diagnóstico, tratamiento y seguimiento de la ambliopía en menores de 18 años con el fin de apoyar al personal de salud en los diferentes servicios encargados de la atención.

Materiales y métodos: Se conformó un grupo interdisciplinario para desarrollar la guía. Se definieron alcance, objetivos, preguntas y desenlaces de la guía. Se realizó una búsqueda de guías sobre manejo de Ambliopía, las guías encontradas fueron calificadas con el Instrumento AGREE II. La Guía de Práctica Clínica (GPC) de Ambliopía de la Asociación Americana de Oftalmología AAO del año 2012 (1) cumplió con los requisitos para realizar adopción del conjunto de evidencia y adaptación de recomendaciones. Con el fin de actualizar la citada guía, se realizó una búsqueda de literatura de revisiones sistemáticas, ensayos clínicos, estudios de cohorte, estudios de casos y controles en las bases de datos MEDLINE, EMBASE y CENTRAL publicados desde un año antes de la fecha de búsquedas realizadas por la Guía de la AAO. Se evaluó la calidad metodológica de los artículos seleccionados. Se elaboraron las tablas de evidencia por medio del software GRADEpro® 3.6 y se generaron las recomendaciones bajo la metodología GRADE.
Resultados: Se formularon recomendaciones para la prevención, detección temprana, diagnóstico, tratamiento y seguimiento de la ambliopía en menores de 18 años. Adicionalmente se presentan varias preguntas generales que sirven al lector para contextualizarse en el tema de la GPC pero que no generan recomendaciones.
𝔸-curves on log smooth varieties
Authors: Chen Qile , Zhu Yi 
Published: July 2017

Abstract
In this paper, we study

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-connected varieties from log geometry point of view, and prove a criterion for

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-connectedness. As applications, we provide many interesting examples of

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{\mathbb{A}^{1}}

-connected varieties in the case of complements of ample divisors, and the case of homogeneous spaces. We also obtain a logarithmic version of Hartshorne conjecture characterizing projective spaces and affine spaces.
Production of recombinant porin from Y. pseudotuberculosis in a water-soluble form for pseudotuberculosis diagnostics
Authors: Golotin Vasily , Portnyagina Olga , Chopenko Natalia , Kim Natalia , Rasskazov Valery , Novikova Olga 
Published: July 2017

AbstractOmpF porin from the outer membrane ofYersinia pseudotuberculosiswas cloned into pET-40b(+) plasmid. UsingE. coliRosetta (DE3) strain, MX medium, IPTG concentration of 0.2 mmand post-induction cultivation at 14°C overnight allowed us to obtain a water-soluble form of the recombinant protein (rs-OmpF). Rs-OmpF was shown to have the ordered spatial structure at the levels of secondary and tertiary structure. Rs-OmpF was found to be effective as diagnostic antigen in ELISA for pseudotuberculosis diagnostics.
Medical Image Reliability Verification Using Hash Signatures and Sequential Square Encoding
Authors: Ranjani J. Jennifer , Babu M. 
Published: July 2017

Abstract
Increased growth of information technology in healthcare has led to a situation where the security of patient information is more important and is a critical issue. The aim of the proposed algorithm is to provide a framework to verify the integrity of the medical images. In this paper, the integrity of the medical images is verified by embedding hash signatures using the sequential square embedding technique. This technique is as efficient as the diamond encoding technique but with increased payload capability. The medical image is first divided into the region of interest (ROI) block and the signature block. The hash signatures are determined by dividing the ROI into nonoverlapping blocks. During the data hiding stage, the hash signatures are embedded in randomly chosen pixel pairs in the signature block using the sequential square encoding (SSE) technique. In the experimental results, the data hiding capacity of the proposed SSE technique is verified in terms of peak signal-to-noise ratio. Also, the medical image integrity is substantiated by comparing the L2 norm between computed and extracted hash signatures. Modifications such as contrast enhancement, rotation, scaling, and changing the image information result in increased L2 norm; thus, the integrity of the medical images can be verified. The parameters required for embedding, such as the embedding parameter and the seed for random sequence generation, are encrypted and communicated to the receiving end. Hence, the proposed algorithm provides a secure framework for medical image integrity verification.
Beyond the Myth of the ‘Good Italian’. Recent Trends in the Study of the Italian Occupation of Southeastern Europe during the Second World War
Authors: Fonzi Paolo 
Published: July 2017

Abstract
This article surveys the existing literature on the occupation policy Italy conducted in Southeastern Europe during the Second World War. The whole subject was largely neglected by scholars of contemporary Italian history up to the 1990s, but in the last twenty years a consistent flow of studies has begun to appear. The reasons for the previous disregard of the topic and, now, the growing interest in it are investigated in the first part of this article. The second part focuses on work done in recent years. It evaluates the strengths and weaknesses of this new literature, and maps out a series of a blank spots that should be addressed by future research.
Rethinking the Place of the Second World War in the Contemporary History of Albania
Authors: Kera Gentiana 
Published: July 2017

Abstract
The Second World War in Albania was a central topic of socialist historiography because of the importance laid upon the National Liberation War for the legitimation of the establishment of communist rule in 1944. History writing was a very centralized process, controlled by party institutions responsible for safeguarding the implementation of Marxist‒Leninist principles and party lines. Since the 1990s, the history of the Second World War has been revised in the framework of a general revision of Albanian national history. History writing developed as an open process and now included historians from countries other than Albania, as opposed to the previous state socialist isolation. The extent to which the war history had been distorted and manipulated during socialism has influenced the subsequent process of rewriting that first focused on adjusting the existing narratives. Thus, despite an increasing variety of research topics, the historiography on wartime Albania has remained dominated by political and military history, and by the national master narrative.
Application of rps16 Intron and trnL-trnF Intergenic Spacer Sequences to Identify Rengas clone Riau
Authors: Roslim Dewi Indriyani , Herman Herman 
Published: July 2017

<p>Rengas clone Riau has been identified using morphological characters and molecular technique with a <em>psbA-trnH</em> intergenic spacer, however, this method can only determine its taxonomic status at genus level, namely <em>Gluta</em> sp. This study reports application two DNA barcodes, i.e. <em>rps16 </em>intron<em> </em>and <em>trnL-trnF</em> intergenic spacer, to identify Rengas clone Riau. The methods included collection of the leaves from Kajuik Lake, total DNA isolation, electrophoresis, PCR (polymerase chain reaction), gel purification and sequencing. The <em>rps16 </em>intron size was 659 bp and the <em>trnL-trnF </em>intergenic spacer was 527 bp. The BLASTn analysis showed that sequences of the <em>rps16 </em>intron and the <em>trnL-trnF </em>intergenic spacer of <em>Gluta</em> sp clone Riau had 100% similarity to those of <em>G. renghas </em>deposited in GenBank. These results were supported by high max score, high total score, query cover = 100%, and E-value = 0. The dendrograms also showed the closest relationship of <em>Gluta</em> sp clone Riau with <em>G. renghas </em>deposited in GenBank compared to other species of <em>Gluta</em>. In conclusion, this study succeeded in identifying Rengas clone Riau as <em>Gluta renghas</em> by using sequences of the <em>rps16 </em>intron and the <em>trnL-trnF</em> intergenic spacer. A combination of DNA barcodes could be applied to identify various plants as long as the database for the DNA barcodes is available in public database such as GenBank. </p>
Gene Expression Networks in the Murine Pulmonary Myocardium Provide Insight into the Pathobiology of Atrial Fibrillation
Authors: Boutilier Jordan K , Taylor Rhonda L , Mann Tracy , McNamara Elyshia , Hoffman Gary J , Kenny Jacob , Dilley Rodney J , Henry Peter , Morahan Grant , Laing Nigel G , Nowak Kristen J 
Published: July 2017

AbstractThe pulmonary myocardium is a muscular coat surrounding the pulmonary and caval veins. Although its definitive physiological function is unknown, it may have a pathological role as the source of ectopic beats initiating atrial fibrillation. How the pulmonary myocardium gains pacemaker function is not clearly defined, although recent evidence indicates that changed transcriptional gene expression networks are at fault. The gene expression profile of this distinct cell type in situ was examined to investigate underlying molecular events that might contribute to atrial fibrillation. Via systems genetics, a whole-lung transcriptome data set from the BXD recombinant inbred mouse resource was analyzed, uncovering a pulmonary cardiomyocyte gene network of 24 transcripts, coordinately regulated by chromosome 1 and 2 loci. Promoter enrichment analysis and interrogation of publicly available ChIP-seq data suggested that transcription of this gene network may be regulated by the concerted activity of NKX2-5, serum response factor, myocyte enhancer factor 2, and also, at a post-transcriptional level, by RNA binding protein motif 20. Gene ontology terms indicate that this gene network overlaps with molecular markers of the stressed heart. Therefore, we propose that perturbed regulation of this gene network might lead to altered calcium handling, myocyte growth, and contractile force contributing to the aberrant electrophysiological properties observed in atrial fibrillation. We reveal novel molecular interactions and pathways representing possible therapeutic targets for atrial fibrillation. In addition, we highlight the utility of recombinant inbred mouse resources in detecting and characterizing gene expression networks of relatively small populations of cells that have a pathological significance.
Resistance to Dislodgement of REBILDA® Post System to Intraradicular Dentin
Authors: Ross DDS Daphne , Filloy Esna DDS Carlos E. , Ramírez-Barrantes DDS, MSD, PhD Juan Carlos 
Published: July 2017

Currently there is controversy in the literature about clinical and adhesive effectiveness with respect to adhesive systems aimed to root reinforcement. Thus, the objective of this study was to evaluate the Push-Out bond strength between the Rebilda® post system and the intraradicular dentine. Thus, 28 unirradicular teeth were used, cut and standardized in 16 mm. The root segments were submitted to endodontic treatment; and then randomly divided into two groups, Group 1 (n = 14): Rebilda® DC + Futurabond DC; Group 2 (n = 14): RelyX ARC + Adper Scothbond Multipurpose Plus. Ten specimens from each group were submitted to the Push-Out Test. The remaining 4 specimens from each group were prepared for Scanning Electron Microscopy (SEM) in order to evaluate the formation of resinous extensions at the post-cement-dentin interface. Group 2 showed better results when compared to Group 1 regarding bond strength and in formation of resinous extensions or tags, but there was no statistically significant difference (p>0.05). It was concluded that the REBILDA® Post System promotes adequate bond strength to intraradicular dentin.
The state of the local immune status, the content of neopterin and cortisol in different variants of preterm labor
Authors: Katkova Nadezhda Yu. , Bodrikova Olga I. , Sergeeva Anzhelika V. , Andosova Larisa D. , Shahova Ksenia A. , Bezrukova Irina M. , Pokusaeva Kseniya B. , Ryzhova Nadezhda K. 
Published: July 2017

Premature labour (PL) is one of the most actual and unsolved problem of obstetrics. There are many data in the li terature about the role of the disturbed ratio of pro- and antiinflammatory cytokines, neopterin in the implementation of PL. Many authors support the theory of the predominant fetus factor in the initiation of PL.
The goal of our research is studying of the characteristics of the local immune status, neopterin and cortisol levels in various variants of preterm labour.
Materials and methods. 77 patients were divided into 2 groups. The main group (52 pregnant women with PL) was also divided into 2 subgroups: the first (1A) subgroup consisted of 28 pregnant women with premature rupture of membranes (PROM) without regular labour contractions. Another subgroup (1B) was presented by 24 women with labour activity and unruptured amniotic sac (true PL). In the control group we included 25 women with term labour. The level of the expression of mRNA genes of a congenital immunity in a cervical canal by the test-system ImmunoQuantex (IL1B, IL10, IL18, TNF2, TLR4, GATA3, CD68, B2M), as well as serum levels of neopterin and cortisol. The results were analyzed by standard statistical methods.
Results. There were no significant difference in the expression levels of most of the genes of innate immunity between the study groups (p > 0.05). The investigation of expression of TLR4, GATA3 genes in different types of PL revealed a significant decrease (p < 0.05) in patients with PROM (1A subgroup). In addition in the 1A subgroup the inflammation index was higher (Me = 99,5%, p < 0.01). There were no fundamental difference in the state of the local immune status between groups of true preterm and term labour. Analysis of neopterin content among the subjects showed a significant increase in the main group (PL) compared with the control group (p = 0.0064). The comparison of the neopterin level between different variants of PL had a higher index (p < 0.025). The concentration of cortisol in the study groups had no principle difference from the main (PL) group and control group (p > 0.05). The maximum cortisol level was found in the subgroup 1B (true PL), which is significantly higher than in the subgroup 1A (with PROM) and in the control group (p < 0.01).
Conclusion. The difference in the state of local immune status in different variants of premature labour demonstrates different mechanisms of initiation of preterm labour. It is likely that the ratio of TLR4/GATA3 and index of inflammation determins the onset of preterm labour. The level of neopterin can be used as a marker of the onset of PL. The increase of cortisol determines the role of the fetus factor in the onset of labour.
Pregnancy outcomes features in patients with different severity of asthma
Authors: Lavrova Olga V. , Shapovalova Elena A. , Dymarskaya Yulia R 
Published: July 2017

Purpose of the study. The study of the peculiarities and outcomes of pregnancy and neonatal status in patients with bronchial asthma (BA).
Materials and methods. Studied the course of pregnancy and delivery 1800 women suffering from BA. Patients were conducted and surveyed throughout the period of gestation simultaneously with pulmonologist and obstetrician; thus it was formed a complex of treatment and preventive measures, made recommendations for the primary prevention of allergic diseases of unborn child.
Results. The increase in pregnancy complications in patients with asthma is directly related to the lack of control of the disease, especially in the first trimester of gestation. The lack of ade quate treatment of asthma increases the risk of different pregnancy complications, which has a direct effect on the health status of newborns.
Conclusion. Even severe asthma, is not a contraindication to pregnancy. The main condition for the safety pregnancy and delivery is the timely appointment of a set of preventive and therapeutic measures for control of the disease that not only improve the quality of life of women during gestation, but also improve health status of newborns.
The experience of vaginal birth after cesarean delivery in the Maternity home No 13 of Saint Petersburg
Authors: Leonova Margarita D. , Frederiks Elena V. , Dymarskaya Yulia R. 
Published: July 2017

Introduction. In developed countries the attempts of vaginal delivery after cesarian section are not an unjustified risk, but considered the most favorable outcome. In Russia, unfortunately, obstetricians do not risk offering a vaginal birth to pregnant women after cesarian section, and outpatient doctors often adjust the abdominal delivery from early stages of pregnancy.
The aim of the study: to identify specifics of labor and outcome of delivery for vaginal birth after previous cesarean and determine possible ways to reduce the frequency of abdominal delivery in these patients.
Materials and methods. We conducted a retrospective analysis of 337 histories of delivery of patients after previous cesarean in 2016 in “Maternity hospital No 13”. The main group consisted of 189 patients to whom vaginal birth was planned, of which 82 patients completed the birth in accordance with the previous plan (subgroup 1) and 107 women completed cesarean section (group 2). The control group consisted of 148 women who had cesarean delivery without trial vaginal delivery.
Results. Among the indications for the first cesarean section in the subgroup 1 were: breech malpresentation – 19.7%, fetal hypoxia – 22.4% and abnormalities of the uterine contractile activity – 13.2%. The most common indications for a second operation in the 2nd subgroup were: premature rupture of amniotic fluid and absence of spontaneous labor (28%), lack of cervical muturity (21.5%), abnormalities of the uterine contractile activity (18.7%), fetal hypoxia (14%), abnormal preliminary period (13.1%), placental abruption (1.9%), absence of the effect of induction (amniotomy) (1.9%), cepalopelvic disproportion (0.9%). Thus, the percentage of success of vaginal delivery was 43.3%. At the same time, the fact of the presence of uterine contractions during the previous delivery did not affect the mode of delivery in this pregnancy. The volume of blood loss in cases of vaginal delivery was significantly less than in the subgroups of patients delivered by cesarean section.
Conclusions. The analysis may lead to reviewing indications and terma for the birth after cesarean. Reserve groups have been defined for high chances of vaginal delivery: prolongation of pregnancy up to 41 weeks, induction and augmentation of labor, conservative management of labor with presumed macrosomia, that may help reduce the frequency of repeated abdominal delivery, development of intra- and postoperative complications.