bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endogenous Oxytocin, Vasopressin and Aggression in Domestic Dogs
Authors: MacLean Evan L. , Gesquiere Laurence R. , Gruen Margaret E. , Sherman Barbara L. , Martin W. Lance , Carter C. Sue 
Published: June 2017

AbstractAggressive behavior in dogs poses public health and animal welfare concerns, however the biological mechanisms regulating dog aggression are not well understood. We investigated the relationships between endogenous plasma oxytocin (OT) and vasopressin (AVP) – neuropeptides that have been linked to affiliative and aggressive behavior in other mammalian species – and aggression in domestic dogs. We first validated enzyme-linked immunosorbent assays (ELISAs) for the measurement of free (unbound) and total (free + bound) OT and AVP in dog plasma. In Experiment 1 we evaluated behavioral and neuroendocrine differences between a population of pet dogs with a history of chronic aggression toward conspecifics and a matched control group. Dogs with a history of aggression exhibited more aggressive behavior during simulated encounters with conspecifics, and had lower free, but higher total plasma AVP than matched controls, but there were no group differences for OT. In Experiment 2 we compared OT and AVP concentrations between pet dogs and a population of assistance dogs that have been bred for affiliative and non-aggressive temperaments, and investigated neuroendocrine predictors of individual differences in social behavior within the assistance dog population. Compared to pet dogs, assistance dogs had higher free and total OT, but there were no differences in either measure for AVP. Within the assistance dog population, dogs who behaved more aggressively toward a threatening stranger had higher total AVP than dogs who did not. Collectively these data suggest that endogenous OT and AVP may play critical roles in shaping dog social behavior, including aspects of both affiliation and aggression.
Validation of Salivary Oxytocin and Vasopressin as Biomarkers in Domestic Dogs
Authors: MacLean Evan L. , Gesquiere Laurence R. , Gee Nancy , Levy Kerinne , Lance Martin W. , Carter C. Sue 
Published: June 2017

AbstractBackgroundOxytocin (OT) and Vasopressin (AVP) are phylogenetically conserved neuropeptides with effects on social behavior, cognition and stress responses. Although OT and AVP are most commonly measured in blood, urine and cerebrospinal fluid (CSF), these approaches present an array of challenges including concerns related to the invasiveness of sample collection, the potential for matrix interference in immunoassays, and whether samples can be collected at precise time points to assess event-linked endocrine responses.New MethodWe validated enzyme-linked immunosorbent assays (ELISAs) for the measurement of salivary OT and AVP in domestic dogs.ResultsBoth OT and AVP were present in dog saliva and detectable by ELISA and high performance liquid chromatography – mass spectrometry (HPLC-MS). OT concentrations in dog saliva were much higher than those typically detected in humans. OT concentrations in the same samples analyzed with and without sample extraction were highly correlated, but this was not true for AVP. ELISA validation studies revealed good accuracy and parallelism, both with and without solid phase extraction. Collection of salivary samples with different synthetic swabs, or following salivary stimulation or the consumption of food led to variance in results. However, samples collected from the same dogs using different techniques tended to be positively correlated. We detected concurrent elevations in salivary and plasma OT during nursing.Comparison with Existing MethodsThere are currently no other validated methods for measuring OT/AVP in dog saliva.ConclusionsOT and AVP are present in dog saliva, and ELISAs for their detection are methodologically valid.
COMPUTATIONAL COMPLEX PREDATOR-PREY DYNAMICS
Authors: Chaudhuri Adwitiya , Hassan SK. Sarif 
Published: June 2017

ABSTRACTTwo species predator-prey with stage structure of mature and immature mathematical models are studied over the last few decades.Xin-an Zhang et alstudied a mathematical model with stage structure of two species in 2010. In this article, an attempt has been made to comprehend the coupled predator-prey dynamics with mature-immature stage structure and compare the dynamics with the existing model. The present model studied byXin-an Zhang et alis purely realistic with assumptions of positive parameters. From the mathematical curiosity, we wonder to investigate the same with complex parameters and compared with the foreseen results. In addition, the present model is slightly modified to see some new dynamics of some additional fixed point including the previous fixed points.
Analysis of the survival capacity of mutual funds: a systematic review of the literature
Authors: Fabregat-Aibar Laura , Terceño Antonio , Barberà-Mariné M. Glòria 
Published: June 2017

Purpose
The purpose of this paper is to carry out a literature review to determine which variables have the greatest impact on the survival capacity of mutual funds, and if these variables also have an influence on the various ways in which mutual funds disappear.

Design/methodology/approach
The authors carry out a systematic review of the literature on mutual funds and identify the main features that affect their capacity for survival.

Findings
The results show that most of the articles are based on data from the US market and that the two most studied variables are the return and the size of the fund. Furthermore, the relationship between the behaviour of variables and the disappearance of funds has mainly been analysed by comparing surviving and non-surviving funds, but without specifying the way in which they disappeared. Finally, the results show that there is no single methodology for examining the survival of funds.

Originality/value
In the financial literature, no previous literature review has focused on the factors that influence the survival capacity of mutual funds. The authors consider that this review will provide a broader and more realistic vision of the level of academic interest in this field and identify any gaps that exist in the literature available.
The Impact of Projected Climate Change Scenarios on Nitrogen Yield at a Regional Scale for the Contiguous United States
Authors: Alam Md Jahangir , Goodall Jonathan L. , Bowes Benjamin D. , Girvetz Evan H. 
Published: June 2017

AbstractImproved understanding of the potential regional impacts of projected climatic changes on nitrogen yield is needed to inform water resources management throughout the United States (U.S.). The objective of this research is to look broadly at watersheds in the contiguous U.S. to assess the potential regional impact of changes in precipitation (P) and air temperature (T) on nitrogen yield. The SPAtially Referenced Regression On Watershed attributes model and downscaled P and T outputs from 14 general circulation models were used to explore impacts on nitrogen yield. Results of the analysis suggest that projected changes in P and T will decrease nitrogen yield for the majority of the contiguous U.S., including the watersheds of the Chesapeake Bay and Gulf of Mexico. Some regions, however, such as the Pacific Northwest and Northern California, are projected to face climatic conditions that, according to the model results, may increase nitrogen yield. Combining the projections of climate‐driven changes in nitrogen yield with projected changes in watershed nitrogen inputs could help water resource managers develop regionally specific, long‐term strategies to mitigate nitrogen pollution.
EMPIRE, COMMUNITY, AND CULTURE ON THE MIDDLE EUPHRATES. DURENES, PALMYRENES, VILLAGERS, AND SOLDIERS
Authors: KAIZER TED 
Published: June 2017

Abstract
The focus of this paper is on the Middle Euphrates: Dura-Europos as its best-known urban settlement; a series of villages known mostly from two papyrological dossiers situated along the river; and the military stations on the Euphrates. The paper asks questions about the impact (or lack of it) of the culture of Palmyra on the region's communities. It is argued that Dura-Europos remains our best case study for social and religious life in a Near Eastern small town under the Roman empire, and that the only evidence that actually makes the town look potentially ‘untypical’ is the idiosyncratic source material related to its Palmyrene inhabitants. The paper also questions the traditional periodization of Dura's history and puts forward the hypothesis that at two points during the so-called ‘Parthian phase’ Palmyrenes took advantage of a power vacuum along the Middle Euphrates and became the dominant military factor in the region.
Twelve‐month use of herbal medicines as a remedy for mental health problems in Japan: A cross‐national analysis of World Mental Health Survey data
Authors: Iwanaga Mai , Iwanaga Hiroo , Kawakami Norito ,   On behalf of the World Mental Health Japan Survey Group
Published: June 2017

AbstractAimThe purpose of this study was to clarify the frequencies and sociodemographic and other characteristics around use of herbal medicine as a remedy for mental health problems in Japan.MethodsData from the World Mental Health Japan (WMHJ) Survey and US National Comorbidity Survey Replications were analyzed. The WMHJ was conducted in 2002 to 2006, with 4129 respondents. National Comorbidity Survey Replications was conducted in 2002 to 2003, with 9282 respondents. The interview asked the respondents about their use of several types of herbs for mental health problems. Frequencies of use of herbal medicine were compared between Japan and the United States. Multiple logistic regression analyses were conducted to determine sociodemographic and mental health‐related correlates of 12‐month herbal medicine use. Relevant sampling weights were used to adjust for the sampling designs.ResultsThe proportion for use of herbal medicines as a remedy for mental health problems in the past 12 months was lower (0.4%) in Japan than that in the United States (3.7%). Low education in both countries (P < .05) was significantly associated with nonuse of herbal medicine. Any anxiety disorder in Japan was significantly associated with herbal medicine use (P < .01), while any mental disorder categories were significantly associated in the United States (P < .01).DiscussionThe frequency for use of herbal medicine among patients with mental health problems in the past 12 months was much lower in Japan compared to the United States. Persons with high educational attainment and anxiety disorders used herbal medicine as a remedy for mental health problems more frequently in Japan.
The Arts as a Venue for Developmental Science: Realizing a Latent Opportunity
Authors: Goldstein Thalia R. , Lerner Matthew D. , Winner Ellen 
Published: June 2017

Children in all cultures readily engage in artistic activities, yet the arts (dance, drama, drawing, and music) have traditionally been marginal topics in the discipline of developmental science. We argue that developmental psychologists cannot afford to ignore such naturalistic activities that involve so many basic phenomena—attention, engagement, motivation, emotion regulation, understanding of others, and so on. Despite historical issues with research methodologies and overdrawn conclusions, a current wave of methodologically rigorous studies shows the depth of arts learning, as well as how arts engagement can be harnessed for transfer to other skills. Here, we present 21 exemplary research case studies, covering an age range of 18 months to 17 years old and discuss how the arts are no more difficult to study than other real‐world developmental phenomena and deserve a thorough examination.
Behavioural implications of traditional treatment and closed‐loop automated insulin delivery systems in Type 1 diabetes: applying a cognitive restraint theory framework
Authors: Kahkoska A. R. , Mayer‐Davis E. J. , Hood K. K. , Maahs D. M. , Burger K. S. 
Published: June 2017

AbstractAs the prevalence of obesity in Type 1 diabetes rises, the effects of emerging therapy options should be considered in the context of both weight and glycaemic control outcomes. Artificial pancreas device systems will ‘close the loop’ between blood glucose monitoring and automated insulin delivery and may transform day‐to‐day dietary management for people with Type 1 diabetes in multiple ways. In the present review, we draw directly from cognitive restraint theory to consider unintended impacts that closed‐loop systems may have on ingestive behaviour and food intake. We provide a brief overview of dietary restraint theory and its relation to weight status in the general population, discuss the role of restraint in traditional Type 1 diabetes treatment, and lastly, use this restraint framework to discuss the possible behavioural implications and opportunities of closed‐loop systems in the treatment of Type 1 diabetes. We hypothesize that adopting closed‐loop systems will lift the diligence and restriction that characterizes Type 1 diabetes today, thus requiring a transition from a restrained eating behaviour to a non‐restrained eating behaviour. Furthermore, we suggest this transition be leveraged as an opportunity to teach people lifelong eating behaviour to promote healthy weight status by incorporating education and cognitive reappraisal. Our aim was to use a transdisciplinary approach to highlight critical aspects of the emerging closed‐loop technologies relating to eating behaviour and weight effects and to promote discussion of strategies to optimize long‐term health in Type 1 diabetes via two key outcomes: glycaemic control and weight management.
Spontaneous intercostal artery bleeding in a hemodialysis patient
Authors: Durey Areum , Kim Young Sam , Kim Ah Jin 
Published: June 2017

AbstractSpontaneous rupture of an intercostal artery (ICA) is a rare but could be a life‐threatening emergency requiring prompt diagnosis and intervention for optimal outcome. We report a patient presented with swelling in his right‐side back which started immediately after scheduled hemodialysis and continued to increase in size. Contrast computed tomography scan revealed soft tissue attenuated lesion with internal enhancing dots which suggested expanding hematoma with active bleeding. Arteriography detected focal contrast extravasation from seventh ICA, and transcatheter arterial embolization was successfully done. To the best of our knowledge, this is the first report describing spontaneous bleeding of ICA in a hemodialysis patient.
Survey: nutrition, body condition and activities of dogs in Switzerland
Authors: Gerstner K. , Liesegang A. 
Published: June 2017

SummaryInterest in species‐appropriate activities and nutrition of dogs increases. A huge variety of feedstuff available, myths and different feeding theories confuse dog owners and lead to inadequate nutrition of their pets. As one result, obesity in pets can be observed with a high incidence in veterinary practice. Although comorbidities of obesity are well known, only few pet owners realize consequently the necessity of weight reduction to support their pet's health. We hypothesized that pet owners in Switzerland underestimate body condition of their dogs and are unsure about how to manage nutritional challenges. This study assessed the current nutrition, owner's perception of body weight and body condition score (BCS) of their dog. At a dog exhibition, dog owners filled in a questionnaire on age, breed, activity, housing, nutrition and source of information for questions concerning nutrition. Owners evaluated the BCS with the help of a poster and determined the ideal weight of their dog. Body weight was measured and BCS evaluated by two veterinarians. The study included 43 bitches [25 (58%) spayed] and 35 male dogs [21 (60%) neutered] with an age of 4.7 ± 3.6 years (mean ± STD). Average current body weight was 18.9 kg ± 14.1 and corresponded approximately to the ideal body weight estimated by the owners (18.6 kg ± 14.1). Four (5%) of the dogs were judged by the owners to be underweight, 55 (70%) ideal, 14 (18%) overweight and five (6%) obese. Owner's evaluation of BCS averaged 4.54 ± 1.13; veterinary's evaluation was significantly higher with 5.20 ± 1.20 (difference of 0.77 ± 0.59; P < 0.05). Although the awareness of the importance of adequate nutrition and activity for pets is rising among pet owners, they are overwhelmed by the variety of diets and sources of information available. This might lead to malnutrition and identifies a clear need for competent specialists of pet nutrition.
The future of dream science
Authors: Bulkeley Kelly 
Published: June 2017

AbstractThis article describes the future prospects of scientific dream research. Three frontiers of investigation hold special promise: neuroscientific studies of the brain–mind system's activities during sleep (such as during lucid dreaming); systematic analyses of large collections of dream reports from diverse populations of people; and psychotherapeutic explorations of the multiple dimensions of personal and collective meaning woven into the dream experiences of each individual. Several helpful books on the science of sleep and dreaming are mentioned for further study.
Blastomyces dermatitidis peritonitis complicating peritoneal dialysis
Authors: Sanghvi Yogesh , Somers Douglas 
Published: June 2017

AbstractFungal peritonitis is an uncommon complication in peritoneal dialysis patients. We report a case of blastomyces dermatitis peritonitis in a nonimmunocompromised peritoneal dialysis patient, who initially presented with symptoms of lower extremity weakness and altered mental status. Peritoneal blastomycosis is rare condition and not previously reported in end stage renal disease patients on peritoneal dialysis. Fungal peritonitis can present with subtle clinical findings so a high index of suspicion is needed as early detection and treatment may decrease mortality and morbidity.
КЛІНІЧНИЙ ВИПАДОК ЗАВІЗНОЇ ТРОПІЧНОЇ МАЛЯРІЇ НА БУКОВИНІ
Authors: Boyko Yu. I. , Moskaliuk V. D. , Andrushchak M. O. , Sokolenko M. O. , Holiar O. I. 
Published: June 2017

Малярія – трансмісивна інфекційна хвороба, якій властиві періодичні напади гарячки, збільшення печінки та селезінки, анемія. Її спричиняють п’ять видів плазмодіїв: триденну малярію - P. vivax, чотириденну - P. malariae, особливий вид триденної - P.ovale, тропічну - P. falciparum та раніше невідому knowlesi-малярію - P. knowlesi.Малярія продовжує залишатись великою проблемою сучасної медицини. Загальна частка захворюваності на малярію становить 2,6 % від усіх захворювань у світі. Поширеність малярії залежить від соціальних, природних та біологічних факторів. Завезені випадки малярії з тропіків можуть з’явитися у помірному кліматі в будь-який час. Значну проблему становить лікування цієї недуги у зв’язку із відсутністю протималярійних препаратів в Україні.
Мікробіологічна характеристика та динаміка змін біоценозу тканин ясен у хворих на генералізований катаральний гінгівіт із хронічним та загостреним перебігом під впливом проведеної комплексної терапії
Authors: Kuzniak N. B. , Shostenko A. A. 
Published: June 2017

Generalized catarrhal gingivitis occupies one of the first places among diseases of periodontal tissues in young people, which is confirmed by numerous studies of both foreign and domestic scientists.The aim of the study – to examine the condition of microbiocenosis of gingival tissues in patients with generalized catarrhal gingivitis with various clinical course, assessment of the effect of the proposed step-wise complex therapy on the clinical and laboratory indices of the disease.Materials and Methods. The article presents the data of a comparative analysis of gingival tissue microbiocoenos is peculiarities and the results of correction of the indices changes in 82 patients with generalized catarrhal gingivitis with variable clinical course. The objective state of the oral cavity and gums was established on the basis of the dynamics of the following tests: a simplified hygiene index (OHI-S), Müllmann, Cowel, and papillary-marginal-alveolar index (PMA).Results and Discussion. To determine the biocenosis of gingival tissues, a classical bacterial culture method was used to determine the quantitative and specific composition of the microflora. Opportunistic streptococcal microflora of the oral cavity was found to occupy a leading role in the development of chronic catarrhal gingivitis, while staphylococci and the fungi of Candida genus are the main agents provoking exacerbations. A comprehensive treatment was elaborated and introduced into practice supposing the use of professional hygienic measures, anti-inflammatory, antibacterial, immunomodulating drugs and probiotics at different stages of treatment. Conclusions. The use of traditional antibiotic therapy in patients with chronic generalized catarrhal gingivitis with additional inclusion of bifidobacterin and cycloferon optimized the effectiveness of treatment: recovery of gum tissue was achieved in 93.5 % of patients and was accompanied by complete elimination of possible pathogens in the gingival tissues.
Прогностичні маркери проліферації та апоптозу в пацієнтів на вузлові форми зоба на фоні автоіму-нного тиреоїдиту
Authors: Bedenyuk A. D. , Sheremet M. I. , Sydorchuk L. P. , Shidlovskyi V. O. 
Published: June 2017

Мета роботи: вивчити процеси апоптозу та проліферації в пункційному матеріалі щитоподібної залози (ЩЗ) при вузловому зобі на фоні автоімунного тиреоїдиту ВЗАІТ з використанням імуногістохімічного методу дослідження, а також визначити індекс проліферативної активності.Матеріали і методи. На пункційному матеріалі ЩЗ, отриманому від 75 хворих із гістологічно верифікованим діагнозом ВЗАІТ, проведено імуногістохімічне дослідження шляхом використання моноклональних антитіл проти Fas, FasL, Bcl-2, P53 та Ki67 антигенів.Результати досліджень та їх обговорення. Результати показали ступінь проліферативної активності тканини ЩЗ при ВЗАІТ. Виявлено високу проліферативну активність лімфоїдної тканини, помірну проліферативну активність тиреоцитів у ділянці лімфоїдної інфільтрації і низьку – поза нею. Виражена експресія Fas та FasL на тиреоцитах, у ділянках лімфоїдної інфільтрації побічно свідчить про те, що при ВЗАІТ відбуваються імунологічно зумовлені процеси апоптозу тиреоцитів. Збільшення кількості імунореактивних клітин, що експресують Ki67 у ділянці лімфоїдної інфільтрації і деструкції тиреоцитів, свідчить про регенерацію фолікулярного епітелію як компенсаторно-пристосувальну реакцію органа. Виражена експресія bsl-2 у лімфоцитах запобігає вхід клітин в апоптоз і подовжує час виживання клітин. Спостерігалася висока експресія протеїну р53 в ядрах тиреоцитів та фолікулярних просвітах, яку можна пояснити мутаціями гена р53, що дозволяє клітинам знайти толерантність до апоптичної дії ефекторів імунної системи.