bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-Term Follow-Up in Patients with Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features (NIFTP) Without a Suspicion of Persistent Disease in Postoperative Assessment
Authors: Rosario Pedro , Mourão Gabriela , Oliveira Luís , Calsolari Maria 
Published: November 2017

AbstractThe objective was to determine whether negative assessment after surgery is a predictor of no relevant change of the results in subsequent evaluations in patients with noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP). Six months after surgery, “absence of persistent disease” was defined when concentration of thyroglobulin (Tg) is ≤2 ng/ml in patients undergoing total thyroidectomy and ≤10 ng/ml in those undergoing lobectomy, in the absence of antithyroglobulin antibodies (TgAb), and neck ultrasonography (US) without abnormalities. One hundred thirteen patients met the definition of “absence of persistent disease”. The patients were followed up for 18–150 months. None of the patients developed structural disease. In the 56 patients undergoing total thyroidectomy, 380 Tg measurements were obtained and an increase in concentrations was not observed in any of them. During the same period, 332 US scans were performed and a suspicious lymph node was detected on only one occasion, but was not metastatic on fine needle aspiration (FNA). In the 57 patients undergoing lobectomy, 382 Tg measurements were obtained and increases or persistent concentrations>10 ng/ml were not observed in any patient. During the same period, 376 US scans were performed and nodules with an indication for FNA were detected in 4 patients, but malignancy was not confirmed in any of them. Finally, TgAb were not elevated in any of the 762 measurements obtained from the 113 patients. After complete resection of NIFTP, negative postoperative assessment can be used to exclude the need for long-term repetition of these tests.
Quality Control of Valerianae Radix by Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) Spectroscopy
Authors: Nikzad-Langerodi Ramin , Arth Katharina , Klatte-Asselmeyer Valerie , Bressler Sabine , Saukel Johannes , Reznicek Gottfried , Dobeš Christoph 
Published: November 2017

Abstract(Acetoxy-)valerenic acid and total essential oil content are important quality attributes of pharmacy grade valerian root (Valerianae radix). Traditional analysis of these quantities is time-consuming and necessitates (harmful) solvents. Here we investigated an application of attenuated total reflection Fourier transform infrared spectroscopy for extractionless analysis of these quality attributes on a representative sample comprising 260 wild-crafted individuals covering the Central European taxonomic diversity of the Valeriana officinalis L. s. l. species aggregate with its three major ploidy cytotypes (i.e., di-, tetra- and octoploid). Calibration models were built by orthogonal partial least squares regression for quantitative analysis of (acetoxy-)valerenic acid and total essential oil content. For the latter, we propose a simplistic protocol involving apolar extraction followed by gas chromatography as a reference method for multivariate calibration in order to handle the analysis of samples taken from individual plants. We found good predictive ability of chemometric models for quantification of valerenic acid, acetoxyvalerenic acid, total sesquiterpenoid acid, and essential oil content with a root mean squared error of cross-validation of 0.064, 0.043, and 0.09 and root mean squared error of prediction of 0.066, 0.057, and 0.09 (% content), respectively. Orthogonal partial least squares discriminant analysis revealed good discriminability between the most productive phenotype (i.e., the octoploid cytotype) in terms of sesquiterpenoid acids, and the less productive ones (i.e., di- and tetraploid). All in all, our results demonstrate the application of attenuated total reflection Fourier transform infrared spectroscopy for rapid, extractionless estimation of the most important quality attributes of valerian root and minimally invasive identification of the most productive phenotype in terms of sesquiterpenoid acids.
Regeneration, restoration and resurrection: scholastic inquiries into the nature of bodily growth and decay
Authors: Gilleard Chris 
Published: November 2017

AbstractBeginning in the twelfth century, a renaissance in Western European learning took place as law, medicine, natural philosophy and theology began to emerge as academic disciplines. Functioning in the context of a Christian world view, concerns over the ‘truth of human nature’ and the status of the body led numerous scholastic writers to focus on matters of the body, its growth and decay, ageing and longevity, life and death. Such issues that had long preoccupied the world of antiquity were re-oriented by the juxtaposition of medicine, philosophy and theology in the schools of Bologna, Montpelier and Paris. Stimulated in part by theological questions concerning the state of the body at the time of creation, after the fall and its re-constitution at the resurrection, the introduction of newly translated works by Aristotle, Avicenna and Galen saw these concerns expand into systematic attempts to explain ageing, longevity and the preservation of health. Within this tradition, Arnold of Villanova’s treatise on the radical moisture serves as an important illustration of these developments. While his writing was rooted in classical medicine and philosophy, less orthodox undercurrents can be detected seeking to preserve youth and extend life by alchemy and magic. Such treatises vied with the orthodoxies of Aristotle and Avicenna, while claiming the authority of the learned doctors themselves. This paper concludes by suggesting that both traditions–the orthodox and the heterodox–are evident to this day, even if couched in different terminologies.
Regenerative medicine: from the laboratory looking out
Authors: Edwards Jennifer , Thomas Richard , Guilliatt Robert 
Published: November 2017

AbstractRegenerative medicine has a rich and pluralistic history, characterised by a patchwork of innovation and blind alleys. As scientific researchers, our understanding of this hybrid field of regeneration in a historical and cultural context is far from complete, in part due to the range of non-medical contributory disciplines and a fascination with the future directions of research. This paper explores the different definitions of regenerative medicine and highlights issues faced in regenerative medicine research. We argue that a closer relationship between regenerative medicine and the humanities would enable researchers to better understand the historical context, ethical implications and public perception of this rapidly developing field. In many cases, this would be through better awareness of the existing expertise available in humanities research, which is often not visible to those in the laboratory.
Estimating the Size Selectivity of Trap Nets using a Gill-Net Selectivity Experiment: Method Development and Application to Lake Whitefish in Lake Huron
Authors: Zhao Yingming , Morbey Yolanda E. 
Published: November 2017

Abstract
Fisheries management requires information about the size selectivity of the fishing gears, but often the experimental data to estimate size selectivity are absent. We developed a two-stage method to use data from an experimental survey for one type of gear (gill nets) to estimate the size selectivity of another type of gear (trap nets) based on the commercial catch data from both gear types, and we applied this method to Lake Whitefish Coregonus clupeaformis in Lake Huron. In stage I, an information-theoretic approach (Akaike's information criterion) was used to select among five candidate models for the size selectivity of experimental gill nets. A double logistic function (a dome-shaped curve skewed to the right) was chosen as the best model to describe the size selectivity of gill nets targeting Lake Whitefish. In stage II, we estimated the size selectivity of trap nets by applying the model of size selectivity from experimental gill nets to commercial catch data from trap-net and gill-net fisheries operating in a similar region and temporal period. Trap-net selectivity was fitted by using a symmetric logistic equation. This two-stage method predicted that 513-mm FL Lake Whitefish are fully selected by gill nets with a mesh size of 114 mm, whereas ≥615-mm FL fish are fully selected by commercial trap nets.
Received April 12, 2017; accepted September 8, 2017 Published online November 9, 2017
Explaining the Third Reich: Swedish students' causal reasoning about the Nazi seizure of power in Germany
Authors: Wendell Joakim 
Published: November 2017

ABSTRACTThe topic of this study is how Swedish students aged 15–16 use causal reasoning in history when given a high‐stakes task about explaining a historically significant event, the rise of the Nazi regime in Germany. The study is based on student texts from the Swedish national test in history. The student texts are mainly analysed with regards to how many, and what kinds of, causal factors are used by the students. The study finds that while most students are able to combine agents and situational factors in their explanations, the explanations show a recurring theme of combining a generic sense of economic crisis with Hitler and the German people as the important agents, to the detriment of other causes that could open up for different interpretations of why the Nazi regime came to power. To counteract this, the study suggests increased emphasis on some contextual factors in teaching practices.
Higher education policy in Canada and Germany: Assessing multi-level and multi-actor coordination bodies for policy-making in federal systems
Authors: Jungblut Jens , Rexe Deanna 
Published: November 2017

Abstract
Modern governments are increasingly faced with problems of policy coordination. However, coordination does not come naturally to organizations as it demands overcoming institutionalized working modes. Thus, countries have to find ways to tackle these problems to ensure efficient provision of public services. This contribution focuses on a specific and complex case, namely policy coordination for higher education policy in federal systems. The main research interest is to analyse the way in which coordination bodies responsible for higher education policy in two federal countries, Canada and Germany, organize their activities. Through this the study contributes to the understanding of the relevance of policy coordination in multi-level and multi-actor policy-making environments as well as the particular institutions that are dedicated to this task. Both coordination bodies are found to have many commonalities. However, the persisting differences, which can be traced to constitutional surroundings, also stress the importance of local conditions.
Higher education governance and policy: an introduction to multi-issue, multi-level and multi-actor dynamics
Authors: Chou Meng-Hsuan , Jungblut Jens , Ravinet Pauline , Vukasovic Martina 
Published: November 2017

AbstractThis thematic issue introduces the multifaceted nature of contemporary public policy – its multi-level, multi-actor and multi-issue features – using the case of higher education policies from around the world. To do so, this introduction first describes how higher education as a policy sector should be garnering far more attention from scholars interested in political, economic and social transformation. A framework for identifying and accounting for how the ‘multi-s’ characteristics configure and re-configure public policy is then introduced. Next, this thematic issue’s contributions are summarized with highlights of how they bring to life the different ‘multi-s’ features. This introduction concludes with a discussion of what the proposed framework of the ‘multi-s’ offers to studies of higher education policy coordination. In so doing, the objectives of this thematic issue are to highlight what the case of higher education policy coordination offers to studies of public policy and to initiate a dialogue between all social scientists and practitioners interested in the increased complexity of governing, producing and using knowledge today.
Higher education governance and policy in China: managing decentralization and transnationalism
Authors: Mok Ka Ho , Han Xiao 
Published: November 2017

Abstract
China has experienced significant social, economic and political transformations since its economic reform started in the late 1970s. Considerable changes in its policy-making and implementation approaches have also emerged. Confronted with the intensified tension between the call for efficiency and strong pressure to improve social welfare, the Chinese government had no choice but to become instrumentally pragmatic in adopting different governance strategies to address the increasingly complex social, economic and political developments. Thus, neoliberal tenets were introduced. This article sets out to examine, against the wider policy context, how neoliberal tenets, particularly its emphasis on market principles, have been injected in higher education governance. This article aims to explore how the multi-faceted dynamics shaped the development of transnational higher education and influenced the governance of Sino-foreign cooperation universities.
The irony of epistemic learning: epistemic communities, policy learning and the case of Europe’s hormones saga
Authors: Dunlop Claire A 
Published: November 2017

Abstract
Epistemic communities are at their most powerful in novel and technically complex policy issues when decision-makers’ and stakeholders’ understandings are rudimentary. A successful epistemic community reduces uncertainty through policy learning. These lessons enable policy actors to recognize their preferences thus making such issues more tractable. However, policy learning is dynamic and has various modes. Where an epistemic community’s advice points in unfavourable policy directions, rival lessons may be crafted by policy actors thus threatening an epistemic community’s place as principal teacher on an issue. What happens to the influence of epistemic communities that do not attend to these alternative interpretations? Can epistemic communities teach in the ‘wrong’ mode? Using the empirical case of the long-running hormone growth promoters saga in the European Union (EU) we show how, even in complex technical issues, learning in the epistemic mode may not dominate for long. Specifically, we identify a key barrier to epistemic communities’ influence neglected in the literature: the ‘irony of epistemic learning’. In setting the foundational knowledge on novel issues, epistemic communities provide non-specialist governance actors with the resources to oppose the very knowledge these experts have created thereby curtailing their influence. We conclude with a discussion about whether epistemic communities can and should overcome this irony.
The limitations of policy learning: a constructivist perspective on expertise and policy dynamics in Dutch migrant integration policies
Authors: Scholten Peter 
Published: November 2017

Abstract
This article zooms in on the role of policy learning in non-incremental policy change. Can policy learning contribute to ‘policy punctuations’ or ‘paradigmatic change’? This question is addressed from a constructivist angle. Within the constructivist approach debate rages on whether, and if so under what conditions, there could be a relationship between policy learning and policy change. The discourse coalition framework renounces the cognitivist concept of policy learning, whereas the critical frame analysis framework claims that critical reflection at the level of policy frames can lead to fundamental ‘frame shifts’. This article reviews these two constructivist frameworks for policy analysis in terms of how they conceptualize and theorize the relation between policy learning and policy change. Besides offering a discussion of the theoretical assumptions of the two constructivist approaches that have been selected, this article offers an empirical congruence analysis of learning and change. This congruence analysis will be applied to one specific case: migrant integration policy-making in the Netherlands (2000–2015). This involves a clear case study where various non-incremental policy changes have taken place, from an integrationist to an assimilationist approach, which makes it a revelatory case for an in-depth study of policy learning and policy change.
Ruling out learning and change? Lessons from urban flood mitigation
Authors: Witting Antje 
Published: November 2017

Abstract
This article shows how particular rule configurations can create conditions for learning from experimentation on an operation level. It does so by using the IAD framework in a diagnostic analysis of decisions to fund the development of drainage in the Denver Metropolitan Area before and after the 2013 Colorado Flood. The discussion first synthesizes recent developments in this research area. Then, it demonstrates how formal institutional analysis can be used to address existing gaps. To conclude, recommendations for further research to develop our understanding of the link between learning and change are presented.
Wicked tendencies in policy problems: rethinking the distinction between social and technical problems
Authors: Newman Joshua , Head Brian W 
Published: November 2017

AbstractComplex or intractable policy problems, often called ‘wicked’ problems, have been a feature of public policy research since the early 1970s. Observers have generally assumed that these wicked problems constitute a distinct category of policy problems, based on the notion that some problems – those characterised as substantially technical or scientific in nature – lend themselves to traditional linear problem-solving methods, whereas other problems that are social in nature tend to be wicked. By examining three cases where scientific knowledge is central to the debate – climate change, genetically modified foods and hydraulic fracturing – we argue that all policy problems can exhibit wicked tendencies, regardless of the amount of scientific information available to decision-makers. Therefore, the reliance on increased information in resolving wicked problems is unlikely to be sufficient or effective.
When, why and how institutional change takes place: a systematic review and a future research agenda on the importance of policy entrepreneurship in macroeconomic bureaucracies
Authors: Bakir Caner , Gunduz K Aydin 
Published: November 2017

Abstract
Political science and public policy scholars have long emphasised the importance of understanding institutional change and policy entrepreneurship. This review article is a response to this call in the context of reform in macroeconomic bureaucracies. Adopting a ‘systematic’ approach to reviewing the literature, this paper investigates when, why and how institutional reform in key monetary and fiscal macroeconomic bureaucracies (i.e. central banks, treasuries, and ministries of finance) takes place. It reviews 29 selected articles on reforms in these bureaucracies published in Thomson & Reuters Web of Knowledge’s Social Science Citation Index, JSTOR, Sage and Wiley databases from 1980 to 2015. It shows that the current state of knowledge about institutional change in key macroeconomic bureaucracies is characterised by a lack of sufficient bridge-building among variants of institutional approaches as well as between institutional theory and public policy theory, resulting in persistent knowledge gaps. Against this background, the present review contributes to the body of knowledge on this topic in two main areas. First, it reviews the literature systematically to provide an overview of the key theoretical and empirical characteristics of when, how and why institutional reform takes place in these bureaucracies. Second, it identifies gaps and future avenues of research to stimulate progress in this important area of study.
For safety’s sake: the strategies of institutional entrepreneurs and bureaucratic reforms in Swedish crisis management, 2001–2009
Authors: Petridou Evangelia , Sparf Jörgen 
Published: November 2017

Abstract
This study focuses on the bureaucratic reforms in Sweden which resulted in the creation of the Secretariat for Crisis Management and the Swedish Civil Contingencies Agency. We investigate the mechanisms that lead to divergent change through the critical juncture analytical approach. The study’s findings suggest that the bureaucratic reforms were the result of the critical juncture between 2001 and 2009, which included, inter alia, the release of a commission of inquiry report, a major political crisis and a national election. Moreover, we situate entrepreneurial agency in this analysis while we contribute to the theorization of institutional entrepreneurship by focusing on the implementation stage of institutional change. In order to overcome the institutional resistance stemming from an attempt to preserve the existing power structures, institutional entrepreneurs use the following three strategies: (i) the strategy of listening; (ii) the strategy of advertising early success and (iii) the strategy of picking up the phone.
Research on application model of blockchain technology in distributed electricity market
Authors: Cheng S , Zeng B , Huang Y Z 
Published: November 2017

Abstract
In the context of current energy Internet, the emergence of a large number of energy productive consumers will create a new business model. In the decentralized electricity market, the cost of traditional centralized solution construction, management and maintenance is too high, and it is difficult to support the collection, transmission, reception, storage and analysis of massive data. To provide a solution to this phenomenon, we apply the blockchain technology to this distributed electricity market to achieve peer to peer transactions in the power systems. The blockchain technology which is very popular nowadays will be used in power system to establish a credible direct transaction between devices. At first, this article analyzes the future direction of the development of power systems, studies the characteristics of decentralized power systems and summarizes the main issues in the development process. Then, we analyze the basic characteristics of blockchain and put forward a new transaction framework in consideration of problems existing in current energy market. The transaction framework is based on the blockchain technology in the distributed electricity market and includes the pricing method, the power transaction system architecture, various modules of the trading system and the details of the whole transaction system runtime. This framework provides a viable solution for increasingly complex energy transactions.
Modelling the behaviour of fishers and fishes
Authors: Clark Colin W 
Published: November 2017

AbstractI describe my personal evolution as a modeller of behaviour, both human and (non-human) animal behaviour, using dynamic state-variable models. At first I worked in renewable resource Economics, especially the economics of marine fisheries where I collaborated extensively with Gordon R. Munro. Subsequently, in collaboration with Marc Mangel (and many field biologists) I worked in Behavioural Ecology. Mathematical models have played a major role in both of these subjects, but until recently mostly static models were used, on the grounds that dynamic (not to mention stochastic) models were too difficult to work with. I express the hope that our use of relatively simple (but not too simple) dynamic models has established the fact that such models can be extremely helpful, perhaps essential, in understanding many aspects of behaviour.