bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intake of green-plant membrane with dietary oil suppresses postprandial hypertriglyceridemia in rats via promoting excretion of bile acids
Authors: Matsuda Hiroko , Ooi Shinpei , Otokozawa Ryo , Kumazaki Kodai , Udagawa Eri , Asakura Masaya , Suzuki Daisuke , Shirai Takaaki 
Published: December 2017

Abstract
Green-plant membrane is a phytonutrient present in green leafy vegetables at high concentration. Postprandial increases in blood triglyceride levels result in insulin resistance and type 2 diabetes. Additionally, dietary life and eating order also affect postprandial hypertriglyceridemia. In this study, the effects of once-daily intake of green-plant membrane with dietary oil on postprandial hypertriglyceridemia were investigated in vitro and in vivo. In vitro, green-plant membrane bound hydrophobic bile acids but did not inhibit pancreatic lipase activity. Following the administration, green-plant membrane with dietary oil in rats, oral fat tolerance tests, increases in serum triglycerides levels were significantly reduced. Moreover, fecal total lipid and bile acid volumes were significantly increased in rats that administered 200 mg/mL green-plant membrane. These results suggest that green-plant membrane with dietary oil inhibits dietary fat absorption via promotion of bile acid excretion in feces and the effectiveness of eating green-plant membrane, such as green leafy vegetables, with meals.
Rhetorical Accretion and Rhetorical Criticism in William Hazlitt’sEloquence of the British Senate
Authors: Homar Katie 
Published: December 2017

ABSTRACTThis paper examines William Hazlitt’s collection, Eloquence of the British Senate (1807), alongside our interest in reception, accretion, and the rhetorical culture of Parliament. I trace Hazlitt’s interpretation of oratory, including his analysis of remediated, printed speech. Hazlitt investigates the circulation and power of oratory in modern print culture, while beginning a multidisciplinary, career-long interest in rhetoric. By mapping how Hazlitt criticizes the status quo while avoiding partisan exposes of corruption, I argue he thinks like a critical rhetorician in ways that enrich our histories of nineteenth-century rhetoric and help us reflect on our own enterprise as historians of rhetoric.
Voices of the rational and aesthetic in Jung: thermodynamics resonating into complexity
Authors: Schenk Ronald 
Published: December 2017

ABSTRACTJung's writing displays many perspectives, each of which is undergirded by a distinct set of assumptions, style of language, and sensibility of world and psyche. This paper traces some of these perspectives with an eye toward showing how the contemporary cutting edge science of complexity, in fact, is anticipated by and embodied in Jung's work, especially that which gives expression to the psyche as an aesthetic enterprise, particularly alchemy.
How many things are there?
Authors: Beaney Michael 
Published: December 2017

Abstract
‘How many things are there?’ introduces Gottlob Frege (1848–1925), one of the main founders of analytic philosophy whose central concern was with the nature of mathematics, and arithmetic in particular. It considers the question ‘How many things are there?’, concluding a simple answer is not permitted without specifying the relevant concept(s) by means of which to think of the things. If how to answer a given question is not immediately obvious, then we need to identify its possible meanings. Perhaps we will find the intended or relevant meaning by understanding the context; if not, then we may need to imagine possible contexts in which the question has an answer.
Do you know what I mean?
Authors: Beaney Michael 
Published: December 2017

Abstract
From the very origins of philosophy, philosophers have been especially conscious of the inadequacies and limitations of language. But they have disagreed on whether this reflects a corresponding deficiency in thought, on what its explanation and implications are, and on how we should respond—in short, on what this itself means. ‘Do you know what I mean?’ explains that in actual cases of analysis, three different dimensions—interpretive, decompositional, and regressive—are typically involved. It also introduces G. E. Moore (1873–1958) who, alongside Russell, inaugurated analytic philosophy in Britain. Moore’s main interests lay with epistemology (the theory of knowledge) and ethics. The paradox of analysis is also discussed.
Development of the place-based Adelante social marketing campaign for prevention of substance use, sexual risk and violence among Latino immigrant youth
Authors: Andrade E L , Evans W D , Barrett N D , Cleary S D , Edberg M C , Alvayero R D , Kierstead E C , Beltran A 
Published: December 2017

Abstract
Immigrant Latino youth represent a high-risk subgroup that should be targeted with health promotion efforts. However, there are considerable barriers to engagement in health-related programming. Little is known about the engagement possibilities of social marketing campaigns and digital strategies for traditionally ‘hard-to-reach’ immigrants, underscoring the importance of testing these techniques with immigrant Latino adolescents. We developed and piloted a place-based social marketing campaign in coordination with the branded, Positive Youth Development-based (PYD) Adelante intervention targeting risk factors for co-occurring youth substance abuse, sexual risk and violence. Building on prior research, we conducted a four-phase formative research process, and planned the Adelante social marketing campaign based on findings from one group interview and ongoing consultation with Adelante staff (n=8) and four focus groups with youth (n=35). Participants identified four overarching campaign themes, and suggested portrayal of resilient, proud youth who achieved goals despite adversity. Youth guided selection of campaign features and engagement strategies, including message/visual content, stylistic elements, and a mixed language approach. We developed a 12-month campaign to be delivered via print ads, multi-platform social media promotion, contests, youth-generated videos, blog posts, and text messaging. We describe the process and outcome of campaign development and make recommendations for future campaigns.
Institutions, Models of Capitalism and Inequality in Income Distribution: An Empirical Investigation
Authors: Antonelli Gilberto , Calia Pinuccia P , Guidetti Giovanni 
Published: December 2017

AbstractThe article analyses the role of institutions in the determination of income inequality in a sample of OECD countries. Basing on the seminal approach by Amable, the article discusses the theoretical definition of model of capitalism. The basic idea is that each model of capitalism is defined by the cobweb of complementary relationships established among different institutions. Using a set of statistical indicators of the operation of institutions in two different years, 1995 and 2010, the empirical analysis points out five models of capitalism and exhibits how their composition has changed in this lapse of 15 years. In the following sections of the article, we investigate the role played by the model of capitalism in the determination of income distribution, measured through a standard Gini index. After controlling for a set of variables, the econometric evidence shows that different models of capitalism present significantly different levels of income inequality.
Timing and Risk Factors of Postpartum Stroke
Authors: Too Gloria , Wen Timothy , Boehme Amelia K. , Miller Eliza C. , Leffert Lisa R. , Attenello Frank J. , Mack William J. , D'Alton Mary E. , Friedman Alexander M. 
Published: December 2017

OBJECTIVE:
To characterize risk and timing of postpartum stroke readmission after delivery hospitalization discharge.

METHODS:
The Healthcare Cost and Utilization Project's Nationwide Readmissions Database for calendar years 2013 and 2014 was used to perform a retrospective cohort study evaluating risk of readmission for stroke within 60 days of discharge from a delivery hospitalization. Risk was characterized as odds ratios (ORs) with 95% CIs based on whether patients had hypertensive diseases of pregnancy (gestational hypertension or preeclampsia), or chronic hypertension, or neither disorder during the index hospitalization. Adjusted models for stroke readmission risk were created.

RESULTS:
From January 1, 2013, to October 31, 2013, and January 1, 2014, to October 31, 2014, 6,272,136 delivery hospitalizations were included in the analysis. One thousand five hundred five cases of readmission for postpartum stroke were identified. Two hundred fourteen (14.2%) cases of stroke occurred among patients with hypertensive diseases of pregnancy, 66 (4.4%) with chronic hypertension, and 1,225 (81.4%) without hypertension. The majority of stroke readmissions occurred within 10 days of hospital discharge (58.4%), including 53.2% of patients with hypertensive diseases of pregnancy during the index hospitalization, 66.7% with chronic hypertension, and 58.9% with no hypertension. Hypertensive diseases of pregnancy and chronic hypertension were associated with increased risk of stroke readmission compared with no hypertension (OR 1.74, 95% CI 1.33–2.27 and OR 1.88, 95% CI 1.19–2.96, respectively). Median times to readmission were 8.9 days for hypertensive diseases of pregnancy, 7.8 days for chronic hypertension, and 8.3 days without either condition.

CONCLUSION:
Although patients with chronic hypertension and hypertensive diseases of pregnancy are at higher risk of postpartum stroke, they account for a minority of such strokes. The majority of readmissions for postpartum stroke occur within 10 days of discharge; optimal blood pressure management may be particularly important during this period.
Treatment of Low-Risk Endometrial Cancer and Complex Atypical Hyperplasia With the Levonorgestrel-Releasing Intrauterine Device
Authors: Pal Navdeep , Broaddus Russell R. , Urbauer Diana L. , Balakrishnan Nyla , Milbourne Andrea , Schmeler Kathleen M. , Meyer Larissa A. , Soliman Pamela T. , Lu Karen H. , Ramirez Pedro T. , Ramondetta Lois , Bodurka Diane C. , Westin Shannon N. 
Published: December 2017

OBJECTIVE:
To assess efficacy of the levonorgestrel-releasing intrauterine device (LNG-IUD) for treatment of complex atypical hyperplasia or low-grade endometrial cancer.

METHODS:
This retrospective case series included all patients treated with the LNG-IUD for complex atypical hyperplasia or early-grade endometrial cancer from January 2003 to June 2013. Response rates were calculated and the association of response with clinicopathologic factors, including age, body mass index, and uterine size, was determined.

RESULTS:
Forty-six patients diagnosed with complex atypical hyperplasia or early-grade endometrial cancer were treated with the LNG-IUD. Of 32 evaluable patients at the 6-month time point, 15 had complex atypical hyperplasia (47%), nine had G1 endometrial cancer (28%), and eight had grade 2 endometrial cancer (25%). Overall response rate was 75% (95% CI 57–89) at 6 months; 80% (95% CI 52–96) in complex atypical hyperplasia, 67% (95% CI 30–93) in grade 1 endometrial cancer, and 75% (CI 35–97) in grade 2 endometrial cancer. Of the clinicopathologic features evaluated, there was a trend toward the association of lack of exogenous progesterone effect in the pathology specimen with nonresponse to the IUD (P=.05). Median uterine diameter was 1.3 cm larger in women who did not respond to the IUD (P=.04).

CONCLUSION:
Levonorgestrel-releasing IUD therapy for the conservative treatment of complex atypical hyperplasia or early-grade endometrial cancer resulted in return to normal histology in a majority of patients.
Low-Fidelity Simulator for the Standardized Training of Fetoscopic Meningomyelocele Repair
Authors: Belfort Michael A. , Whitehead William E. , Bednov Andrey , Shamshirsaz Alireza A. 
Published: December 2017

BACKGROUND:
Fetoscopic meningomyelocele repair in a gas-filled uterus is a new technique performed in very few centers. There are few opportunities as well as ethical prohibitions on the initial development and subsequent refinement of innovative fetal surgery techniques in humans, and using an animal model is both very expensive and logistically difficult.

METHOD:
We developed a low-fidelity endoscopic fetal surgery simulation using a plastic doll and pieces of chicken breast to simulate a fetal meningomyelocele, and a polyurethane ball to simulate a gas-filled uterus, along with a standard endoscopy system and instruments.

EXPERIENCE:
A unique two-port technique with significant differences from the standard laparoscopic surgery procedure was developed and refined through an iterative phase into a standardized methodology, and the simulator was then used to train three other teams to perform standardized fetoscopic meningomyelocele repair.

CONCLUSION:
A low-fidelity fetoscopic surgery simulator is a useful tool for developing new fetoscopic operations and for training multidisciplinary fetal surgery teams without the need for extensive use of an animal model. This simulator may be used to further explore the human uterus as a new surgical space for additional fetal surgeries.
Clomiphene Stair-Step Protocol for Women With Polycystic Ovary Syndrome
Authors: Jones Tiffanny , Ho Jacqueline R. , Gualtieri Marc , Bruno-Gaston Janet , Chung Karine , Paulson Richard J. , Bendikson Kristin A. 
Published: December 2017

OBJECTIVE:
To compare time to ovulation, ovulation rates, and side effect profile of traditional and the stair-step protocol for ovulation induction using clomiphene citrate in women with polycystic ovary syndrome (PCOS).

METHODS:
We performed a retrospective study of women seeking care for infertility with a diagnosis of PCOS at a university-based infertility clinic from July 2012 to July 2014. We included patients who were resistant to the initial starting dose of 50 mg clomiphene. The primary outcome was time to ovulation. Secondary outcomes included ovulation rates, clinical pregnancy rates, and mild and moderate-to-severe side effects based on dose. For the traditional protocol, higher doses of clomiphene were used each subsequent month if no ovulation occurred. For the stair-step protocol, higher doses of clomiphene were given 7 days after the last dose if no dominant follicles were seen on ultrasonography. Our study had 80% power to detect a 20% difference in ovulation.

RESULTS:
One hundred nine patients were included in the analysis with 66 (60.6%) in the traditional and 43 (39.4%) in the stair-step protocol. Age and body mass index were similar between groups. The time to ovulation was decreased in the stair-step protocol group compared with the traditional protocol group (23.1±0.9 days vs 47.5±6.3 days). Ovulation rates were increased in the stair-step group compared with the traditional group at 150 mg (16 [37%] vs 8 [12%], P=.004) and at 200 mg (9 [21%] vs 3 [5%], P=.01). Pregnancy rates were similar between groups once ovulation was achieved (12 [18.1%] vs 7 [16.3%], P=.08). The stair-step protocol had an increased incidence of mild side effects (vasomotor flushes, headaches, gastrointestinal disturbance, mastalgia, changes in mood; 18 [41%] vs 8 [12%]), but there was no difference in the incidence of severe side effects (headaches, visual disturbances).

CONCLUSION:
For women with PCOS, the stair-step clomiphene protocol is associated with decreased time to ovulation and increased ovulation rates at higher doses when compared with the traditional protocol.
Achieving High Reliability with People, Processes, and Technology
Authors: Saunders Candice L. , Brennan John A. 
Published: December 2017

Summary
High reliability as a corporate value in healthcare can be achieved by meeting the “Quadruple Aim” of improving population health, reducing per capita costs, enhancing the patient experience, and improving provider wellness. This drive starts with the board of trustees, CEO, and other senior leaders who ingrain high reliability throughout the organization. At WellStar Health System, the board developed an ambitious goal to become a top-decile health system in safety and quality metrics. To achieve this goal, WellStar has embarked on a journey toward high reliability and has committed to Lean management practices consistent with the Institute for Healthcare Improvement’s definition of a high-reliability organization (HRO): one that is committed to the prevention of failure, early identification and mitigation of failure, and redesign of processes based on identifiable failures. In the end, a successful HRO can provide safe, effective, patient- and family-centered, timely, efficient, and equitable care through a convergence of people, processes, and technology.
Engaging All Employees in Efforts to Achieve High Reliability
Authors: Benedicto Anne Marie 
Published: December 2017

Dramatic and numerous advances in science, technology, and medicine provide new opportunities to keep people healthy as well as to diagnose, treat, and cure disease. Unfortunately, increasing complexity increases opportunities for mistakes and errors, particularly in healthcare organizations as they struggle to prevent patient harm (Chassin and Loeb 2011). Safety problems persist and harm to patients continues despite widespread attention to the need for improvement (Stelfox et al. 2006).
An engaged and empowered workforce is critical to improving the patient experience, improving health outcomes, and correcting unsafe conditions (Rathert and May 2007). However, all healthcare workers—nurses, physicians, security guards, chaplains, and so many others—are subject to the same stressors and system failures that lead to patient harm. This situation compromises the workforce’s ability to ensure care that is consistently excellent and safe. Patient harm events are further exacerbated by employee fatigue, disengagement, burnout, intimidation, bullying, and violence in the work place.
The Strategic Value of Affiliation Partnerships in Securing Future Relevance
Authors: Saunders Ninfa M. 
Published: December 2017

SUMMARY
Finding the best route to navigate the changing landscape of healthcare has become an obsession for many organizations. Their quest to stay competitive, significant, and ultimately relevant is a continuous discovery process. Many hospitals and health systems have considered affiliations and partnerships as important tactical options. Partnerships can range from loose arrangements, such as nonequity collaborations and management agreements, to total affiliation, as in a merger and acquisition. Whichever option an organization decides to pursue, a comprehensive assessment is necessary to find the best partner—the right fit. Addressing the “why,” “when,” “how,” and “with whom” questions is fundamental. Having the depth and breadth of resources to manage the discovery process is equally important.
Learning from others who have experienced this journey is helpful, as is the support of industry experts. However, one task that cannot be delegated is discerning whether affiliation is right for an organization. That is the responsibility of an organization’s leadership team, which must consider the dynamic forces in play when evaluating an affiliation partnership. Many of the suggested modalities revolve around how the affiliation partnership can provide a value proposition for the entities involved. Furthermore, inevitable challenges emerge when fiercely independent and successful organizations come together at different levels of need and readiness. Anticipating and providing for the potential exit of any member are matters that the partnership must accept and prepare for, and the ability to execute can make or break the trajectory toward a value proposition. A strong resolve to monitor, measure, calibrate, and recalibrate can give a partnership the agility to pivot toward relevance and sustainability.
Stratus Healthcare applied principles of alignment and affiliation in creating the largest collaborative partnership of hospitals in the southeastern United States. Drawing from its affiliation partnership experience with Navicent Health and other member organizations, it has many lessons to share.
Fat Distribution in Schizophrenia Patients
Authors: Sapra Mamta , Lawson Donna , Iranmanesh Ali 
Published: December 2017

Abstract

Background
Introduction of second-generation antipsychotics (SGAs) has reduced neurologic toxicity but are associated with increased weight gain and obesity. The objective of this pilot study is to compare the effects of first-generation antipsychotics (FGAs) and SGAs in patients with schizophrenia on body fat and presumed concomitant metabolic parameters.

Methods
Study compared schizophrenia nondiabetic men treated with FGAs (group 1, n = 5) and men treated with SGAs (group 2, n = 9). Each subject completed psychiatric and endocrine evaluation including severity of psychiatric symptoms, adverse effects, body weight, body composition, and measurements of glucose, insulin, adipokines, and inflammatory markers. Student t test was used for statistical analysis.

Results
Men treated with FGAs had a lower mean body mass index with a trend toward statistical significance (25.3 ± 1.4 vs 29.3 ± 1.7, P = 0.06). Treatment with FGAs was associated with lower waist/height ratio (0.55 ± 0.02 vs 0.62 ± 0.02, P = 0.036) and android fat mass index (0.62 ± 0.01 vs 0.96 ± 0.1, P = 0.03). Homeostasis Model Assessment for insulin resistance values were suggestive of significantly lower peripheral insulin resistance in men treated with FGAs (0.92 ± 0.15 vs 2.3 ± 0.34, P = 0.014).

Conclusions
The results of this study are significant for decreased peripheral insulin resistance in men treated with SGAs in a setting of no significant age difference and only a trend toward higher body mass index, but consistent documentation of increased abdominal fat by 3 different methodologies. Future studies involving larger number of subjects are warranted to verify the present findings.
End-of-Life Care Discussion for Residents With Dementia in Long-Term Care Facilities
Authors: HUANG Hsiu-Li , WENG Li-Chueh , HU Wen-Yu , SHYU Yea-Ing Lotus , YU Wen-Pin , CHEN Kang-Hua 
Published: December 2017

ABSTRACT

Background:
Healthcare professionals play an important role in end-of-life care decisions. Although the factors affecting end-of-life care in long-term care facilities have been well studied in Western contexts, few studies have examined factors affecting end-of-life care discussions for residents with dementia among multidisciplinary professionals in Asian or Taiwanese contexts.

Purpose:
The aim of this study was to explore the factors related to the end-of-life care discussions of registered nurses, social workers, and physicians with residents with dementia and their families.

Methods:
This is a cross-sectional and correlational study. A stratified random sampling was conducted, and self-administered questionnaires were mailed to physicians, registered nurses, and social workers who work in long-term care facilities with accreditation ranks ≥ Grade A in Taiwan.

Results:
Questionnaires were returned by 478 participants (response rate = 94.1%). Fewer than 10% of the participants reported often discussing end-of-life care with residents with dementia and their families. Physicians were significantly more likely to discuss life-sustaining treatment than nurses and social workers. The frequency of professionals discussing advance directives and life-sustaining treatment for residents with dementia was predicted by higher confidence in end-of-life care skills and greater perceived facility support.

Conclusions/Implications for Practice:
Most professionals did not frequently discuss end-of-life care with residents with dementia and their caregivers. Discussions of end-of-life care in long-term care facilities should be promoted by enhancing the confidence of these professionals in providing end-of-life care and creating a supportive environment for end-of-life discussions and care.