bluuebunny/crossref_metadata_2025_split huggingface dataset:
TÉTANO: RELATO DE CASO
Authors: ROMEIRO Yara Eduarda Franco , CRUZ Taís Sepúlveda da , SILVEIRA Ana Eduarda Souza da , OLIVEIRA Fernanda R. P. Soares , LUZ Eveline De Almeida , BRUM Victor Lopes 
Published: July 2017

<p>Tétano, doença infecciosa aguda, não contagiosa, causada pelas exotoxinas do <em>Clostridium tetani</em>, um bacilo Gram-positivo anaeróbio. O bacilo é normalmente encontrado na forma de esporos (e, por isso, pode viver vários anos no meio ambiente), tendo como reservatórios: pele, fezes, terra, poeira das ruas e trato gastrointestinal de animais. A doença pode ser classificada em acidental ou neonatal. A imunidade permanente ocorre com a vacina, e os filhos de mães imunes apresentam imunidade passiva e transitória até quatro meses. <strong>Objetivo:</strong> este estudo objetiva relatar caso de um paciente portador de tétano acidental, que esteve internado no Hospital São José do Avaí (HSJA), Itaperuna-RJ, no período de março a maio de 2017, justificando-se pela gravidade e dificuldade em se concluir o diagnóstico. <strong>Metodologia: </strong>o estudo se iniciou com a coleta de dados no HSJA, entrevistando o paciente e pessoas que estiveram em contato com o enfermo. Além de embasamento teórico, com extensa revisão bibliográfica em busca de fundamentação teórico-metodológica para o desenvolvimento do estudo, foram utilizados recursos como: anamnese, exame físicos, exames laboratoriais e de imagens. <strong>Resultados: </strong>para elucidar o diagnóstico do paciente foram utilizados critérios clínicos e a dosagem de creatino fosfoquinase. Epidemologicamente, existia história de manipulação de solo e criação de animais. <strong>Conclusão: </strong>é necessário atentar-se à importância da profilaxia com vacinação antitetânica e informação da população quanto à procura de profissionais da saúde frente a ferimentos, queimaduras ou traumatismo suspeitos de conterem a exotoxina, direcionando os mesmos para um diagnóstico mais precoce e, consequentemente, um tratamento eficaz. </p>
Efficacy of 1% Metformin Gel in Patients With Moderate and Severe Chronic Periodontitis: A Randomized Controlled Clinical Trial
Authors: Pradeep A.R. , Patnaik Kaushik , Nagpal Kanika , Karvekar Shruti , Guruprasad C.N. , Kumaraswamy K.M. 
Published: July 2017

Background: The aim of this study is to investigate efficacy of metformin (MF) 1% gel as an adjunct to scaling and root planing (SRP) in the treatment of moderate and severe chronic periodontitis (CP).Methods: Seventy patients were categorized into two treatment groups: 1) SRP plus 1% MF and 2) SRP plus placebo. Clinical parameters were recorded at baseline and 3, 6, and 9 months. They included plaque index (PI), modified sulcus bleeding index (mSBI), probing depth (PD), and clinical attachment level (CAL). Radiologic assessment of intrabony defects (IBDs) and percentage defect depth reduction (DDR%) was done at baseline and 6‐ and 9‐month intervals using computer‐aided software. PD, CAL, and DDR% were evaluated in two subgroups in both the placebo and MF group: 1) initial PD of 5 to 7 mm and 2) initial PD of >7 mm.Results: Mean PD reduction and mean CAL gain was found to be greater in the MF group than the placebo group at all visits. Clinical parameters (PD, CAL) in both subgroups, with initial PDs of 5 to 7 and >7 mm, showed significant improvement in the 1% MF group compared with the placebo group. A significantly greater mean DDR% was found in the MF group than the placebo group at 6 and 9 months in both subgroups, 5 to 7 and >7 mm of initial PD.Conclusion: There was a greater decrease in PD and more CAL gain with significant IBD depth reduction at sites treated with SRP plus locally delivered MF in patients with CP in both initial PD = 5 to 7 and >7 mm subgroups compared with placebo.
The Effectiveness of Mangosteen Peels Extract Against The Total of T Lymphocytes in HIV Patients
Authors: Kurniasari Maria Dyah , Dharmana Edi , Gasem Hussein 
Published: July 2017

Introduction: The Province of West Java is one of the highest HIV sufferers in Indonesia that has increased accumulatively in 2013 to 2014. This condition was proven that in 2014 West Java ranked 4th among the provinces with the highest HIV sufferers in Indonesia. HIV has main target to infect a cell that contains of receptor, CD4. CD4 examination routinely is very important to decide HIV replication process. Meanwhile, CD4 test in the laboratory is quite expensive and not always available in every health facilities. Mangosteen peels extract contains of xanthones as an antioxidant, which is needed for body as a prooxidant that can inhibit the replication of HIV and the activity was seen from the total number of lymphocyte.Method: The human experimental research has been done by Randomized Control Group Pretest-Post Test Design. There were 20 patients sample for each group. In group 1, HIV patients with ARV therapy were given mangosteen peels extract and in group 2, they were given placebo capsule. Wilcoxon Smith test and Mann Whitney U test were used to determine the difference between group 1 and group 2.Result: There is no significant difference between lymphocytes (p: 0.102) to HIV patients with ARV in each group examination. Discussion: The ineffectiveness is caused by the phagocytocity and cytoxity of TNF through the increasing of free radicals in HIV patients.
Factors Related to Open Defecation Behavior Among School-Age Children in West Lombok
Authors: Makhfudli Makhfudli , Rachmawati Praba Diyan , Andini Saskiyanti Ari 
Published: July 2017

Introduction: Open defecation behavior is one cause of poor sanitation, which can lead to various diseases. Open defecation behavior related with cultural factors that become a habit in the daily life in a society which was then followed by their children. This study aimed to analyze factors related to the parental behavior of open defecation in school-age children based on the theory of transcultural nursing in Marce, Sedau Community Health Center Area, West Lombok Indonesia Methods: This was a descriptive research design with cross-sectional approach. Samples were taken by simple random sampling technique and obtained 95 parents of children aged 7-12 years. Independent variables were education level, economy level, cultural values and lifestyle, social and family values, religiosity, technology. The dependent variable was open defecation behavior of the parents in school age children. This research was analyzed using Spearman rho test with significance level α = 0.05.Results: education level (p = 0.000; r = 0.390), economy level (p = 0.003; r = 0.298), cultural values and lifestyle (p = 0.000; r = 0.555), social and family (p = 0.000; r = 0.444), religiosity (p = 0.000; r = 0.300), technology (p = 0.000; r = 0354) has a significant relationship with the parents about the open defecation behavior in school age children.Conclusion: the intervention was needed on the factors that influence the open defecation behavior by nurses participating directly to communities to increase public awareness about the importance of healthy defecate in a closet to avoid the disease.
Health Care-Seeking Behaviour of Coastal Communities in Banyuwangi, Indonesia: Results of A Cross-Sectional Survey
Authors: Sebayang Susy Katikana , Astutik Erni , Dewi Desak Made Sintha Kurnia , Mandagi Ayik Mirayanti , Puspikawati Septa Indra 
Published: July 2017

Introduction: Improving health care-seeking behavior of the coastal communities is a pathway to improve their health. This analysis aims to explore the health care-seeking behavior of the coastal communities in Banyuwangi District to recommend the room for improvement for health promotion and health service improvement for these communities.Method: Data from a cross-sectional survey of metabolic syndrome and mental health conducted in coastal communities in Banyuwangi was used for analysis. Randomly selected participants from a list of members of Family Welfare Development Group (Pembinaan Kesejahteraan Keluarga /PKK) were asked for an interview at corresponding village office in Ketapang, Bangsring, Bulu Agung, Grajagan and Kampung Mandar village. Distribution of health care-seeking behaviors was analyzed individually and where possible were segregated by gender and age.Results: More than half of the coastal communities in Banyuwangi District went to health care service to seek health and 7 out of 10 turned to health care service to seek health for their family members. Women more than men turned to health care service when they or their family members fell ill. Private doctors rather than Puskesmas were more popular. Private midwives were the most popular service for antenatal care (ANC) and delivery. Although there was not a clear increase in health care service utilization over time, we found that contraceptive utilization increased with time.Conclusion: The utilization of health care service in Banyuwangi needs to be more promoted especially for men’s health.
Density and Viscosity of Athabasca Bitumen, a Condensate Sample, and Mixtures Applicable for Expanding-Solvent Steam-Assisted-Gravity-Drainage and Liquid-Addition-to-Steam-for-Enhancing-Recovery Processes
Authors: Nourozieh Hossein , Kariznovi Mohammad , Abedi Jalal 
Published: July 2017

Summary
This paper presents the density and viscosity measurements for a condensate sample, Athabasca bitumen, and Athabasca bitumen/condensate mixtures applicable for in-situ bitumen-recovery methods and pipeline transportation. The measurements for the densities and viscosities are reported at different temperatures (ambient to 200°C) and pressures (atmospheric to 10 MPa). For mixtures, a wide range of solvent fractions (5-50 wt%) is investigated. The data for the mixtures are also evaluated with predictive schemes as well as with correlation models representing certain mixing rules proposed in the literature. The results indicate that mixture densities are well represented by the excess-volume method, with an average absolute relative deviation (AARD) of 0.78%. The Bij model predicts the mixture viscosities with an AARD of 11.7%.
Preparation of ureido-functionalized PVA/silica mesoporous fibre membranes via electrospinning for adsorption of Pb2+ and Cu2+ in wastewater
Authors: Zhou Meimei , Tang Weizhen , Luo Pingping , Lyu Jiqiang , Chen Aixia , Qiao Longkai , Nover Daniel 
Published: July 2017

Abstract
Ureido-functionalized mesoporous polyvinyl alcohol/silica composite nanofibre membranes were prepared by electrospinning technology and their application for removal of Pb2+ and Cu2+ from wastewater was discussed. The characteristics of the membranes were investigated by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and N2 adsorption-desorption analysis. Results show that the membranes have long ﬁbrous shapes and worm-like mesoporous micromorphologies. Fourier transform infrared spectroscopy confirmed the membranes were successfully functionalized with ureido groups. Pb2+ and Cu2+ adsorption behavior on the membranes followed a pseudo-second-order nonlinear kinetic model with approximately 30 minutes to equilibrium. Pb2+ adsorption was modelled using a Langmuir isotherm model with maximum adsorption capacity of 26.96 mg g−1. However, Cu2+ adsorption was well described by a Freundlich isotherm model with poor adsorption potential due to the tendency to form chelating complexes with several ureido groups. Notably, the membranes were easily regenerated through acid treatment, and maintained adsorption capacity of 91.87% after five regeneration cycles, showing potential for applications in controlling heavy metals-related pollution and metals reuse.
Hierarchical prediction of industrial water demand based on refined Laspeyres decomposition analysis
Authors: Shang Yizi , Lu Shibao , Gong Jiaguo , Shang Ling , Li Xiaofei , Wei Yongping , Shi Hongwang 
Published: July 2017

Abstract
A recent study decomposed the changes in industrial water use into three hierarchies (output, technology, and structure) using a refined Laspeyres decomposition model, and found monotonous and exclusive trends in the output and technology hierarchies. Based on that research, this study proposes a hierarchical prediction approach to forecast future industrial water demand. Three water demand scenarios (high, medium, and low) were then established based on potential future industrial structural adjustments, and used to predict water demand for the structural hierarchy. The predictive results of this approach were compared with results from a grey prediction model (GPM (1, 1)). The comparison shows that the results of the two approaches were basically identical, differing by less than 10%. Taking Tianjin, China, as a case, and using data from 2003–2012, this study predicts that industrial water demand will continuously increase, reaching 580 million m3, 776.4 million m3, and approximately 1.09 billion m3 by the years 2015, 2020 and 2025 respectively. It is concluded that Tianjin will soon face another water crisis if no immediate measures are taken. This study recommends that Tianjin adjust its industrial structure with water savings as the main objective, and actively seek new sources of water to increase its supply.
Increased Expression of IRE1α Associates with the Resistant Mechanism of Osimertinib (AZD9291)-resistant non-small Cell Lung Cancer HCC827/OSIR Cells
Authors: Tang Zheng-hai , Su Min-Xia , Guo Xia , Jiang Xiao-Ming , Jia Lin , Chen Xiuping , Lu Jin-Jian 
Published: July 2017

Background:
Osimertinib (OSI), also known as AZD9291, is a third-generation epidermal growth
factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that has been approved for the treatment of non-small
cell lung cancer (NSCLC) patients.

Objective:
Establishment of the OSI-resistant HCC827/OSIR cell line and study of its resistant mechanism.

Method:
The anti-proliferative effect was studied through MTT and colony formation assays. The protein expression
was detected by Western blot assay. The gene was silenced by small interfering RNA. The cellular
morphology was observed by using an optical microscope. The viable cell numbers were counted by trypan blue
staining assay.

Results:
The OSI-resistant HCC827/OSIR cells were established on HCC827 cells with naive EGFR-sensitive
mutation, and the resistant effects of HCC827/OSIR cells were confirmed through MTT and colony formation
assays. The IC50s of HCC827/OSIR cells to other EGFR TKIs, such as gefitinib, erlotinib, afatinib, and
rociletinib was higher than that of the HCC827 cells. The anti-proliferative effects of paclitaxel, pemetrexed,
doxorubicin, and fluorouracil in HCC827 and HCC827/OSIR cells were similar. The expression of inositolrequiring
enzyme 1α (IRE1α) was increased after the cells developed resistance to OSI. The number of viable
cells in both cell lines, particularly in HCC827/OSIR cells, was decreased through knockdown of IRE1α or
pretreatment with STF-083010, an IRE1α inhibitor.

Conclusion:
An increased expression of IRE1α may be one of the resistant mechanisms for OSI-resistant
NSCLC.
Flotation of Chromite as Pre-Treatment of Olivine Before Carbonation for CO2 Sequestration
Authors: Turri Laura , Muhr Hervé , Rech Cristielen , Lapicque François 
Published: July 2017

Background and Objective:For the sake of optimal beneficiation of the products formed in the chemical sequestration of CO2on silicates, extraction of the chromite has been carried out prior to carbonation, by flotation in a lab-scale column.Method:Industrial-grade olivine and serpentine were tested. Flow conditionse.g. gas flow rate, stirring, particle diameter of silicates, and physicochemical considerations (composition if the electrolyte solution) have been examined to optimize the separation efficiency in terms of chromite recovery or enrichment factor.Result:The high performance observed with chromite-enriched olivine allows a multistage flotation process from low-chromite minerals blends to be designed.Conclusion:The lower performance with native olivine was attributed to the existence of mixed chromite-silicate particles.
Analyzing Commuters’ Behavior on Egress Trip from Railway Stations in Yogyakarta, Indonesia
Authors: Irawan Muhammad Zudhy , Putri Monika Kristyana , Belgiawan Prawira Fajarinda , Dwitasari Reslyana 
Published: July 2017

Background:

Prambanan Ekspres Railway is known as one of the commuting modes in Yogyakarta, Indonesia. Sufficient egress modes do not support this railway. Due to lack of urban mass transit facilities, the commuters independently utilize a reliable mode for their mobility, for instance by owning a motorcycle and using overnight parking service facility in their non-home-station.

Objective:
This paper aims to understand the commuters’ behavior on their egress trip when they decide to use the train as their main mode.

Methods:
A direct interview survey on the train was conducted during peak hours from Monday to Friday. By implementing stated preference survey, a logit model was used to analyze mode choice decision from the railway station to activity end destination.

Results:
The results indicate that walking distance to the parking area and bus-waiting time have a more significant impact compared to the walking distance to bus stop and in-bus travel time. Furthermore, the high cost of overnight parking also significantly influences the decision of choosing an egress mode. Otherwise, egress trip cost has less significance to encourage commuters’ to shift to bus mode.
DAYA HAMBAT DEKOK KULIT APEL MANALAGI (Malus sylvestris Mill) TERHADAP PERTUMBUHAN Escherichia coli DAN Streptococcus agalactiae PENYEBAB MASTITIS PADA SAPI PERAH
Authors: Surjowardojo Puguh , Susilorini Tri Eko , Benarivo Vasco 
Published: July 2017

Kulit apel manalagi (Malus sylvestris Mill.) mengandung banyak zat aktif yang dapat berfungsi sebagai antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui kemampuan dari dekok kulit apel manalagi (Malus sylvestris Mill.) dalam menghambat pertumbuhan bakteri Escherichia coli dan Streptococcus agalactiae penyebab mastitis pada sapi perah dan menentukan konsentrasi optimal dalam menghambat pertumbuhan bakteri tersebut. Metode yang digunakan yaitu metode difusi sumuran dengan 4 perlakuan dan 5 ulangan. Perlakuan tersebut terdiri dari konsentrasi 10%, 20%, 30% dan iodips sebagai perlakuan standart. Hasil penelitian ini menunjukkan bahwa dekok kulit apel manalagi (Malus sylvestris Mill.) dengan konsentrasi 10%, 20% dan 30% mampu menghambat pertumbuhan bakteri, dimana perlakuan yang paling baik yaitu pada konsentrasi 30%. Hasil perhitungan rata-rata luas zona hambat dekok kulit apel manalagi (Malus sylvestris Mill.) dalam menghambat pertumbuhan bakteri Escherichia coli adalah berbeda sangat nyata (P<0,01) dan hasil perhitungan pada bakteri Streptococcus agalactiae adalah tidak berbeda nyata (P>0,05). Kesimpulan dari hasil penelitian ini adalah konsentrasi 10%, 20% dan 30% dapat menghambat pertumbuhan bakteri Escherichia coli dan Streptococcus agalactiae. Konsentrasi 10%, 20% dan 30% belum dapat mengimbangi kekuatan daya hambat dari iodips dalam menghambat pertumbuhan bakteri Escherichia coli, akan tetapi padaÂ bakteri Streptococcus agalactiae mampu untuk menghambat pertumbuhannya.Â Kata kunci: kulit apel manalagi, dekok, daya hambat antibakteri, bakteri patogen.
KUALITAS SEMEN CAIR SAPI BALI SELAMA PENYIMPANAN SUHU RUANG MENGGUNAKAN PENGENCER SKIM MILK DENGAN PENAMBAHAN FILTRAT KECAMBAH KACANG HIJAU
Authors: Fadilah Zenni Nur , Isnaini Nurul , Ihsan Muhammad Nur 
Published: July 2017

Penelitian ini bertujuan untuk mengetahui kualitas semen cair sapi Bali yang menggunakan pengencer skim milk dengan penambahan filtrat kecambah kacang hijau selama penyimpanan di suhu ruang (29oC). Hasil penelitian diharapkan dapat menjadi kajian ilmiah serta sumber informasi bagi akademisi dan Balai Inseminasi Buatan. Materi penelitian yang digunakan adalah semen segar sapi Bali yang dipelihara secara intensif di BBIB Singosari Malang dengan kriteria umur 6-11 tahun, motilitas massa ++ dan motilitas individu 50-70%. Metode penelitian yang digunakan adalah percobaan laboratorium menggunakan pola Rancangan Acak Kelompok (RAK) dengan 4 perlakuan dan 5 kali ulangan, P0 sebagai kontrol (100% Skim Milk + 0% Filtrat Kecambah Kacang hijau); P1 (98% SM + 2% FKKH); P2 (96% SM + 4% FKKH) dan P3 (94% SM + 6% FKKH). Analisis data yang yang digunakan adalah Analisis Ragam atau Analysis of Variant (ANOVA), apabila terdapat perbedaan yang nyata atau sangat nyata maka dilakukan uji jarak berganda Duncan. Hasil penelitian menunjukkan bahwa penambahan filtrat kecambah kacang hijau ke dalam pengencer skim milk memberikan perbedaan yang tidak nyata (P>0,05) terhadap kualitas semen cair sapi Bali selama penyimpanan suhu ruang (29oC) baik motilitas individu, viabilitas maupun abnormalitas spermatozoa.Â Kata kunci: antioksidan, motilitas, viabilitas, abnormalitas
KUALITAS SPERMATOZOA SWIM UP KAMBING PERANAKAN ETAWAH HASIL PEMBEKUAN MENGGUNAKAN METODE VITRIFIKASI DENGAN PERSENTASE GLISEROL YANG BERBEDA
Authors: Hikamawan Saka Wahyu , Cipatadi Gatot , Wahjuningsih Sri 
Published: July 2017

The objective of this research was to examine the effect of glycerol addition in different percentage to quality of swim up spermatozoa from Etawah Grade buck that frozen with vitrification method. This research was carried out at Frozen Semen Laboratory, Sumbersekar, Faculty of Animal Husbandry, Brawijaya University from February 2016 to March 2016. This research design was experimental laboratory using completely randomized design and the data were analyzed using Analysis of Variance (ANOVA) one way pattern, followed by the multiple test Duncan. There were four treatments in this research (P0= Tris-Yolk + 0% Glycerol, P1= Tris-Yolk + 7% Glycerol, P2= Tris-Yolk + 14% Glycerol, P3= Tris â€“ Yolk + 21% Glycerol). Each treatment consisted of ten replications. The results showed that addition of glycerol was significantly different (P<0,01) on the percentage of post thawing motility, viability, and total spermatozoa motility. It was concluded that addition of glycerol 7% gave the best result on spermatozoa quality.Â Keywords : swim up, glycerol, frozen semen, vitrification, post thawing motility
INHIBITION OF Malus sylvestris Mill. PEELEXTRACT USING ETANOL SOLVENT ON THE GROWTH OF Streptococcus agalactiae AND Escherichia coli CAUSING MASTITIS
Authors: Putra Kanzul Kamal , Setyowati Endang , Susilorini Tri Eko 
Published: July 2017

The purpose of this research was to find the resistibility of Manalagi apple peel extract, using etanol, to the growth of was to determine the antibacterial activity of Manalagi apple peel (Malus sylvestris Mill) extract in various solvent using ethanol concentration against the growth of Streptococcus agalactiae and Escherichia coli bacteria that causing mastitis.The research methodwas experimental using Completely Randomized Design with 4 treatments and 6 replication. The treatments consisted of P1 (10%), P2 (20%), P3 (50%) concentrations and P0 (10%) iodips as the control. The variable measured was diameter of inhibition zone. The data were analyzed using ANOVA and continued by Duncanâ€™s New Multiple Range Test (DMRT) test if there was significantly difference result. The result of the inhibition zone of Manalagi apple peel extract using etanol in preventing the growth of Streptococcus agalactiae and Escherichia coli bacteria was different (P<0,01). In P2 (30%) concentration, the extract resistibility to the growth of Streptococcus agalactiae bacteria was equivalent to P0 (iodips) and in P3 (50%) concentration, the extract resistibility to Escherichia coli bacteria was greater than P0 (iodips). Manalagi apple peel extract using etanol can be used as a natural antiseptic solution for teat dipping on dairy cows. The recommendation from the research was using extract Manalagi apple peel with etanol solvent concentration of 30% as a solution of teat dipping.Â Keywords : Manalagi apple peel, Teat dipping, Mastitis, Streptococcus agalactiaeand Escherichia coli