bluuebunny/crossref_metadata_2025_split huggingface dataset:
Australian Indigenous cancer patients’ self-report of diagnosis, treatment and comorbidity data: how does it compare to medical chart review.
Authors: Maresch Bernardes Christina , Diaz Abbey , Baade Peter , Garvey Gail , Valery Patricia Casarolli 
Published: October 2016

Rationale: The quality of patient-centred care relies upon the reliability of the data used to produce performance measures. The agreement between patient self-report and medical chart review among Aboriginal and Torres Strait Islander cancer patients is unknown.Objective: To examine the concordance between patient self-report and medical chart review in determining cancer type, current and previous cancer treatment, comorbidities and patient characteristics associated with agreement.Method: Aboriginal and Torres Strait Islander cancer patients (≥18 years) who had received cancer treatment in the past 30 days (n=208) were recruited. The prevalence, sensitivity, specificity, total agreement and Kappa coefficients (K) were estimated to determine the agreement (yes + yes; no + no) between self-reported data and medical records.Results: 13.5% of the patients could not accurately identify their cancer type. For treatment variables, raw agreement ranged from 70.5% to 92.4%, although, after correcting for chance, there was a lack of consistency for current radiation and past treatment variables (K= -0.01 to 0.48). Sensitivity and specificity were moderate to high for current surgery and chemotherapy. The greatest crude prevalence difference by data source was observed for comorbidities not specified in the questionnaire. Sensitivity and specificity were high for diabetes. Conclusion: investigators and policy makers may rely upon patient self-report for diabetes, current cancer treatment of surgery and chemotherapy. However, should be cautious when considering patient self-report for past treatment and other comorbid conditions.
Process mapping appointments to identify improvements in care delivered to patients who screen positive for depression
Authors: Kim Bo , Rodrigues Stephanie , Dell Natalie S , Elwy Rani 
Published: October 2016

Rationale, aims and objectives After screening positive for depression, many patients do not receive effective medication or maintain optimal contact with practitioners. Our objective was to examine how appointments that patients have after screening positive may affect the delivery of evidence-based and guideline-concordant depression care. Methods We reviewed treatment records for 271 patients who screened positive for depression in primary care across three United States Veterans Health Administration medical facilities. For each patient, we mapped the process of appointments that took place following the positive screen, noting the number of appointments, the service line in which each appointment was held, as well as whether guideline-concordant depression care was in turn received over four months. Results We found that (i) approximately half of the patients who screened positive had no follow-up appointments, (ii) all patients who had two or more follow-up appointments received some – but not necessarily guideline-concordant – mental health treatment, and (iii) there were distinct patterns across the three facilities regarding which service lines’ appointments most often resulted in treatment. Conclusions Our work offers a novel approach of using data on appointments that patients have after screening positive for depression to shed light on current care practices. The number of post-screening appointments can be an informative process measure for improving depression care to become more guideline-concordant. Facilities vary substantially in terms of which service lines they use to attain guideline-concordance, likely due to notable differences in how their primary care, integrated primary care behavioral health, and mental health services are organized.
A comparative study of the mastery of fundamental movement skills between different cultures
Authors: Dos Santos Fernando Garbeloto , Pacheco Matheus Maia , Basso Luciano , Tani Go 
Published: October 2016

<p>It has been suggested that guidance, encouragement and opportunity are crucial factors for children’s motor development. They are especially important to promote the mastery of fundamental movement skills. The present study investigated the association between two elements related to those factors – proposed curriculum of physical education and the most popular sport in a given country – and the incidence of mastery in the FMS in children from 4 to 10 years of age. In order to carry out a cross-cultural comparison, three studies from different countries (Portugal, China and USA) that used TGMD-II were selected. The results indicated association between proposed curriculum and the number of children mastering FMS. This association increases in older age groups of children from USA, the most structured curriculum related to FMS, presenting the highest average percentage of mastery. Additionally, we did not find association of the most popular sports in a given country with the mastery of the related skill. These results are interpreted as evidence for the importance of guidance on the mastery of FMS.</p><p class="Summary"><span lang="EN-US"><br /></span></p>
Disclosing in utero HIV/ARV exposure to the HIV‐exposed uninfected adolescent: is it necessary?
Authors: Jao Jennifer , Hazra Rohan , Mellins Claude A , Remien Robert H , Abrams Elaine J 
Published: October 2016

IntroductionThe tremendous success of antiretroviral therapy has resulted in a diminishing population of perinatally HIV‐infected children on the one hand and a mounting number of HIV‐exposed uninfected (HEU) children on the other. As the oldest of these HEU children are reaching adolescence, questions have emerged surrounding the implications of HEU status disclosure to these adolescents. This article outlines the arguments for and against disclosure of a child's HEU status.DiscussionDisclosure of a child's HEU status, by definition, requires disclosure of maternal HIV status. It is necessary to weigh the benefits and harms which could occur with disclosure in each of the following domains: psychosocial impact, long‐term physical health of the HEU individual and the public health impact. Does disclosure improve or worsen the psychological health of the HEU individual and extended family unit? Do present data on the long‐term safety of in utero HIV/ARV exposure reveal potential health risks which merit disclosure to the HEU adolescent? What research and public health programmes or systems need to be in place to afford monitoring of HEU individuals and which, if any, of these require disclosure?ConclusionsAt present, it is not clear that there is sufficient evidence on whether long‐term adverse effects are associated with in utero HIV/ARV exposures, making it difficult to mandate universal disclosure. However, as more countries adopt electronic medical record systems, the HEU status of an individual should be an important piece of the health record which follows the infant not only through childhood and adolescence but also adulthood. Clinicians and researchers should continue to approach the dialogue around mother–child disclosure with sensitivity and a cogent consideration of the evolving risks and benefits as new information becomes available while also working to maintain documentation of an individual's perinatal HIV/ARV exposures as a vital part of his/her medical records. As more long‐term adult safety data on in utero HIV/ARV exposures become available these decisions may become clearer, but at this time, they remain complex and multi‐faceted.
Photoresponse in graphene induced by defect engineering
Authors: Du Ruxia , Wang Wenhui , Du Jianxin , Guo Xitao , Liu Er , Bing Dan , Bai Jing 
Published: October 2016

Abstract
We present a photoresponse study on a lateral defect/pristine graphene junction device fabricated by a simple plasma irradiation method. The junction between pristine graphene and plasma-modified graphene was created by controlling the location of Ar+ plasma treatment. We found that a distinct photocurrent was generated at the junction by photocurrent line scanning measurements, and further analysis reveals that the photo-thermoelectric (PTE) effect, instead of the photovoltaic (PV) effect, dominates the photocurrent generation at the interface. Additionally, the obtained results suggest that tuning the defect density could be effective in modulating the optoelectronic performance of junctions in our device.
Achievement of a high-mobility FET with a cloud-aligned composite oxide semiconductor
Authors: Yamazaki Shunpei , Shima Yukinori , Hosaka Yasuharu , Okazaki Kenichi , Koezuka Junichi 
Published: October 2016

Abstract
We have recently discovered that films of a widely used In–Ga–Zn oxide (IGZO) with

have different material composition states when sputter-deposited under different conditions using the same polycrystalline IGZO target. Significant improvements in on-state current and mobility (as high as 40 cm2·V−1·s−1) are obtained. The results of local composition analysis indicate that the deposited film is not composed of any known homogeneous IGZO compound and that the components of this film are separated into two types of nanoparticle regions: one type is composed mainly of GaO
x
and GaZnO
x
, which contribute to on/off (switching) characteristics, and the other is composed mainly of InO
x
and InZnO
x
, which contribute to on-state characteristics. These regions constitute a new type of oxide semiconductor (OS) film. The nanoparticles with a blurry boundary extend like a cloud, probably complementing one another. We consider that this OS film has a novel composition, which can be described as a “cloud-aligned composite OS” (CAC-OS).
Evaluation of reference genes for gene expression in red-tailed phascogale (Phascogale calura) liver, lung, small intestine and spleen
Authors: Ong Oselyne T.W. , Young Lauren J. , Old Julie M. 
Published: October 2016

BackgroundReference genes serve an important role as an endogenous control/standard for data normalisation in gene expression studies. Although reference genes have recently been suggested for marsupials, independent analysis of reference genes on different immune tissues is yet to be tested. Therefore, an assessment of reference genes is needed for the selection of stable, expressed genes across different marsupial tissues.MethodsThe study was conducted on red-tailed phascogales (Phascogale calura) using five juvenile and five adult males. The stability of five reference genes (glyceraldehyde-3-phosphate dehydrogenase,GAPDH;β-actin,ACTB;18SrRNA,18S; 28SrRNA, 28S;and ribosomal protein L13A,RPL13A) was investigated using SYBR Green and analysed with the geNorm application available in qBasePLUSsoftware.ResultsGene stability for juvenile and adult tissue samples combined show thatGAPDHwas most stable in liver and lung tissue, and18Sin small intestine and spleen. While all reference genes were suitable for small intestine and spleen tissues, all reference genes except28Swere stable for lung and only18Sand28Swere stable for liver tissue. Separating the two age groups, we found that two different reference genes were considered stable in juveniles (ACTBandGAPDH) and adults (18Sand28S), andRPL13Awas not stable for juvenile small intestine tissue. Except for28S, all reference genes were stable in juvenile and adult lungs, and all five reference genes were stable in spleen tissue.DiscussionBased on expression stability,ACTBandGAPDHare suitable for all tissues when studying the expression of marsupials in two age groups, except for adult liver tissues. The expression stability between juvenile and adult liver tissue was most unstable, as the stable reference genes for juveniles and adults were different. Juvenile and adult lung, small intestine and spleen share similar stable reference genes, except for small intestine tissues where all reference genes were stable in adults butRPL13Awas not suitable in juveniles.
Saberes e práticas de mães de recém-nascidos prematuros perante a manutenção do aleitamento materno Knowledge and practices of mothers of premature newborns in the mainteining of breastfeeding
Authors: Brod Fernanda Regina , Rocha Daniele Lais Brandalize , Santos Reginaldo Passoni dos 
Published: October 2016

Objetivo: Identificar os saberes e práticas de mães de recém-nascidos prematuros frente à manutenção do aleitamento materno. Método: Estudo qualitativo, com delineamento exploratório. Desenvolveu-se a pesquisa em um Banco de Leite Humano, com dez puérperas durante a hospitalização de seus filhos. Para a coleta de dados, realizaram-se entrevistas presenciais com aplicação de questionário semiestruturado. Analisaram-se as respostas, utilizando-se a Técnica de Análise de Conteúdo. Obteve-se o Certificado de Apresentação para Apreciação Ética, da Pontifícia Universidade Católica do Paraná, sob nº 15743513.3.0000.0020. Resultados: Dos discursos, emergiram duas categorias: A consistência do conhecimento apresentado pelas mães; Impacto da orientação profissional sobre a prática de ordenha do leite materno. Conclusão: mesmo apresentando pouca consistência no conhecimento, observou-se impacto positivo da orientação profissional à prática para ordenha do leite materno.
Cost‐Related Medication Behaviors for Patients With and Without Systemic Autoimmune Rheumatic Diseases
Authors: Yee Jeong , Feldman Candace H. , Oakes Emily G. , Ellrodt Jack , Guan Hongshu , Choi May Y. , Karlson Elizabeth W. , Costenbader Karen H. 
Published: September 2024

ObjectiveMedication nonadherence challenges the management of systemic autoimmune rheumatic diseases (SARDs). We investigated cost‐related medication behaviors among patients with SARDs, and compared them to those of patients without SARDs, in a large diverse cohort across the United States.MethodsAs part of the All of Us (version 7), a nationwide diverse adult cohort with linked electronic health records begun in 2017, participants completed questionnaires concerning cost‐related medication behaviors. Chi‐square tests compared responses between patients with SARDs, by disease and medication type, and to those without SARDs. Logistic regression analyses were used to calculate odds ratios (95% confidence intervals [CIs]).ResultsWe analyzed data from 3,997 patients with SARDs and 73,990 participants without SARDs. After adjustment, patients with versus without SARDs had 1.56 times increased odds of reporting unaffordability of prescription medicines (95% CI 1.43–1.70), 1.43 times increased odds of cost‐related medication nonadherence (95% CI 1.31–1.56), and 1.23 times increased odds of using cost‐reducing strategies (95% CI 1.14–1.32). Patients with SARDs who reported unaffordability were 16.5% less likely to receive a disease‐modifying drug (95% CI 0.70–0.99) but 18.1% more likely to receive glucocorticoids (95% CI 0.99–1.42). In addition, unaffordability of prescription medicines was likely to have 1.27 times increased odds of one to two emergency room visits per year (95% CI 1.03–1.57) and 1.38‐fold increased odds of three or more emergency room visits per year (95% CI 0.96–1.99).ConclusionIn this large diverse cohort, patients with versus without SARDs had more self‐reported cost‐related medication behaviors, and those who reported medication unaffordability received fewer disease‐modifying drugs and had more emergency room visits.
Achieving Ultra‐Narrow‐Band Deep‐Red Electroluminescence By a Soliton‐type Dye Squaraine
Authors: Tan Wenle , Yu Yue , Shi Tianyuan , Zhang Lveting , Gan Hanlin , Wang Bohan , Liu Ganlin , Li Mingke , Ying Lei , Ma Yuguang 
Published: September 2024

AbstractDue to the soliton‐like electronic structural characteristics, cyanine dyes typically exhibit spectral behaviors such as large molar extinction coefficients, narrow spectra, and high fluorescence efficiency. However, their extensive applications as emitters in electroluminescence are largely ignored due to their serious emission quenching in the aggregation state. Herein, it is reported a squaraine dye (a type of cyanine) SQPhEt. At different solution concentrations, the unusual decrease in full‐width at half‐maxima (FWHM) with increasing Stokes shift indicates the fluorescence quenching of SQPhEt in the aggregated state is because of the strong self‐absorption effect. A sensitized device structure can help to reduce the doping concentration of dye, which can effectively suppress self‐absorption. Benefitting from the large molar extinction coefficient of SQPhEt, even at low doping concentrations of 0.1 wt%, efficient Förster energy transfer can be achieved. The corresponding spin‐coating sensitized device based on SQPhEt as the dopant exhibits favorable deep‐red emission at 668 nm with a small FWHM of 0.10 eV.
High‐Efficiency Near‐Infrared Iridium(III) Complexes with Tailored Ligands for Solution‐Processed OLEDs with Maximum EQE of 3.75% at 830 nm
Authors: Li Shaman , Zhang Yanxin , Dai Yu , Xu Jingyi , Meng Qing‐yu , Wen Xue‐liang , Qiao Juan 
Published: September 2024

AbstractThe development of highly efficient pure near‐infrared (NIR) emitting organic materials with emission beyond 800 nm is extremely challenging due to the limitation of the energy gap law. Herein, three efficient NIR emitting iridium(III) complexes are developed adopting pyrido[3,4‐b]pyrazine derivatives as the cyclometalated C^N ligands, namely (Epptt)2Iracac (1), (pptt)2Iracac (2), and (ppCz)2Irtmd (3). Due to the enhanced donor–acceptor interaction inside the ligand, the conjugation‐extended and electron‐richer N‐phenylcarbazole unit at the C‐part of the ligands endows complex 3 with a large bathochromic shift of emission peak from 796 to 862 nm in toluene solution, compared with thieno[3,2‐b]thiophene C‐part in complex 2. The solution‐processed OLEDs based on complex 3 achieved a record high maximum external quantum efficiency of 3.75% and low efficiency roll‐off with the emission peak at 830 nm, a champion efficiency in the Ir(III) based OLEDs with emission peak exceeding 800 nm. This work opens a new avenue for the development of high‐efficiency pure NIR organic emitters based on Ir(III) complexes for various applications.
Embryo‐Derived Cathepsin B Promotes Implantation and Decidualization by Activating Pyroptosis
Authors: Li Meng‐Yuan , Wu Ying , Tang Hao‐Lan , Wang Ying , Li Bo , He Yu‐Ying , Yan Gui‐Jun , Yang Zeng‐Ming 
Published: September 2024

AbstractEmbryo implantation and decidualization are crucial for a successful pregnancy. How the inflammatory response is regulated during these processes is undefined. Pyroptosis is an inflammatory form of cell death mediated by gasdermin D (GSDMD). Through in vivo, cultured epithelial cells and organoids, it is shown that pyroptosis occurs in epithelial cells at the implantation site. Compared with those on day 4 of pseudopregnancy and delayed implantation, pyroptosis‐related protein levels are significantly increased on day 4 of pregnancy and activated implantation, suggesting that blastocysts are involved in regulating pyroptosis. Blastocyst‐derived cathepsin B (CTSB) is stimulated by preimplantation estradiol‐17β and induces pyroptosis in epithelial cells. Pyroptosis‐induced IL‐18 secretion from epithelial cells activates a disintegrin and metalloprotease 12 (ADAM12) to process the epiregulin precursor into mature epiregulin. Epiregulin (EREG) enhances in vitro decidualization in mice. Pyroptosis‐related proteins are detected in the mid‐secretory human endometrium and are elevated in the recurrent implantation failure endometrium. Lipopolysaccharide treatment in pregnant mice causes implantation failure and increases pyroptosis‐related protein levels. Therefore, the data suggest that modest pyroptosis is beneficial for embryo implantation and decidualization. Excessive pyroptosis can be harmful and lead to pregnancy failure.
Kidney Injury Evoked by Fine Particulate Matter: Risk Factor, Causation, Mechanism and Intervention Study
Authors: Hou Tong , Jiang Yuqing , Zhang Jiyang , Hu Renjie , Li Sanduo , Fan Wenjun , Chen Rucheng , Zhang Lu , Li Ran , Qin Li , Gu Weijia , Wu Yue , Zhang Lina , Zeng Xiang , Sun Qinghua , Mao Yingying , Liu Cuiqing 
Published: September 2024

AbstractFine particulate matter (PM2.5) is suggested to pose a severe risk to the kidneys by inducing functional degradation and chronic kidney diseases (CKD). This study aims to explore the nephrotoxicity of PM2.5 exposure and the underlying mechanism. Herein, based on the UK Biobank, it is found that per interquartile range (IQR) increase in PM2.5 is associated with a 6% (95% CI: 1%–11%), 7% (95% CI: 3%–11%), 9% (95% CI: 4%–13%), 11% (95% CI: 9%–13%), and 10% (95% CI: 8%–12%) increase in the risk of nephritis, hydronephrosis, kidney stone, acute renal failure, and CKD, respectively. In experimental study, noticeable kidney injury, which is the initiation of kidney diseases, is observed with PM2.5 exposure in C57BL/6N mice (n = 8), accompanied with oxidative stress, autophagy and pyroptosis. In vitro, HK‐2 cells with PM2.5‐stimulation exhibit tubulopathy, increased reactive oxygen species (ROS) generation and activated pyroptosis and autophagy. All changes are abolished by ROS scavenger of N‐acetyl‐L‐cysteine (NAC) both in vivo and in vitro. In conclusion, the study provides evidence showing that PM2.5 exposure is associated with 5 kinds of kidney diseases by directly inducing nephrotoxicity, in which ROS may be the potential target by triggering autophagy and pyroptosis.
Ferromagnetic–Antiferromagnetic Coupling in Gas‐Phase Synthesized M(Fe, Co, and Ni)–Cr Nanoparticles for Next‐Generation Magnetic Applications
Authors: Bohra Murtaza , Giaremis Stefanos , KS Abisegapriyan , Mathioudaki Stella , Kioseoglou Joseph , Grammatikopoulos Panagiotis 
Published: September 2024

AbstractCombining ferromagnetic–antiferromagnetic materials in nanoalloys (i.e., nanoparticles, NPs, containing more than one element) can create a diverse landscape of potential electronic structures. As a result, a number of their magnetic properties can be manipulated, such as the exchange bias between NP core and shell, the Curie temperature of nanoparticulated samples, or their magnetocaloric effect. In this work, such a family of materials (namely M–Cr NPs where M is Fe, Co, Ni, or some combination of them) is reviewed with respect to the tunability of their magnetic properties via optimized doping with Cr up to its solubility limit. To this end, gas‐phase synthesis has proven a most effective method, allowing excellent control over the physical structure, composition, and chemical ordering of fabricated NPs by appropriately selecting various deposition parameters. Recent advances in this field (both experimental and computational) are distilled to provide a better understanding of the underlying physical laws and point toward new directions for cutting‐edge technological applications. For each property, a relevant potential application is associated, such as memory cells and recording heads, induced hyperthermia treatment, and magnetic cooling, respectively, aspiring to help connect the output of fundamental and applied research with current real‐world challenges.