bluuebunny/crossref_metadata_2025_split huggingface dataset:
Framing the Multi‐Centre Qualitative Research Design as a Novel Methodology for Nursing and Healthcare Research: Reflections and A Methodological Discussion
Authors: Bayuo Jonathan , Wong Frances Kam Yuet , Li Yan , Lu Wenze , Wong Arkers Kwan Ching 
Published: October 2024

ABSTRACTAimTo discuss the multi‐centre qualitative methodology as a unique design, articulate its guiding paradigm/theoretical perspectives, and highlight its methodological and methodical issues. A secondary objective is to generate further scholarly discourse regarding the multi‐centre approach within the broader qualitative research tradition.DesignMethodological discussion.FindingsRather than an emphasis on only experiences, the multi‐centre approach is presented as a unique design which also focuses on uncovering why a phenomenon or problem exists and perceptions regarding the phenomenon/problem. With its focus on capturing multiple subjective realities, the multi‐centre qualitative design is arguably underpinned by pragmatist constructivism which offers a robust framework for researching phenomenon in a way that is both theoretically informed and practically relevant. Methodologically, the multi‐centre qualitative research design emphasises a problem‐centred enquiry, collaborative approach and rigorous study protocols, systematic site selection, contextual immersion and sensitivity and methodical flexibility.ConclusionWith the rapidly evolving nursing and global health landscape, the multi‐centre design lends itself to exploring and capturing perceptions on a larger scale compared to single site studies. Careful planning, availability of adequate resources, rigorous protocols and quality assurance plans are critical to ensuring its success.Implications for Profession and Patient CareThe multi‐centre approach offers the possibility of undertaking the same study across multiple settings/locations which has the potential to improve representation and strengthen transferability.ImpactThis methodological discussion offers clarity regarding the use of the multi‐centre approach and offering strategies for its subsequent uptake in nursing and healthcare research.Reporting MethodNot applicable.Patient and Public ContributionNo patient or public contribution.
Association of Triglyceride‐Glucose Index, Triglyceride to High‐Density Lipoprotein Cholesterol Ratio, and Related Parameters With Prehypertension and Hypertension
Authors: Yang Shijie , Zhang Yuqing , Zhou Zhanyang , Duan Xiaochun 
Published: October 2024

ABSTRACTThe objective of this study was to investigate the association between triglyceride to high‐density lipoprotein cholesterol ratio (TG/HDL‐c), triglyceride‐glucose index (TyG), and related parameters (TyG‐BMI, TyG‐WC) with prehypertension and hypertension over 45 years old. According to the blood pressure diagnosis, the enrolled individuals were divided into two groups, which were prehypertension and hypertension. In multivariate logistic regression analysis, after adjusting for confounders, the highest quartile groups of TG/HDL‐c, TyG, and related parameters showed a significantly increased risk of hypertension compared to the lowest quartile groups, and there was associated with hypertension when comparing the highest TG/HDL‐c to the lowest TG/HDL‐c and corresponding ORs were 1.416 (1.234, 1.625) and 1.029 (0.893, 1.187), respectively. Furthermore, when comparing the fourth quartile to the first quartile of TG/HDL‐c, TyG index, and related parameters, respectively, both corresponding ORs of hypertension were higher than prehypertension. Elevated TyG, TyG‐BMI, TyG‐WC index, and TG/HDL‐c ratio levels were associated with hypertension in individuals over 45 years. Moreover, the receiver operating characteristic curve was used to compare the predictive ability of each parameter in identifying people with hypertension suggested that the TyG‐WC index ([Area under the curve] AUC: 0.601 [CI: 0.588–0.615]), TyG‐BMI, and TyG were more significant than TG/HDL‐c in distinguishing hypertension. However, in the prehypertension population, the area under the ROC curve for TyG‐BMI (0.543 [CI: 0.530–0.556]) was better than that of other parameters. They have the potential to become cost‐effective monitors in the hierarchical management of hypertension.
Prognostic understanding among caregivers of persons with dementia: A scoping review
Authors: Balasubramanian Ishwarya , Andres Ellie Bostwick , Poco Louisa Camille , Malhotra Chetna 
Published: October 2024

AbstractIntroductionDespite the influence of caregivers' prognostic understanding (PU) on the end‐of‐life care for persons with dementia (PwDs), the literature on PU of caregivers of PwDs is sparse. We conducted a scoping review to understand the variation in existing definitions and measurement of caregivers' PU for PwDs. We also aimed to synthesize the prevalence of caregivers' correct PU and the factors (caregiver, PwD and healthcare related) associated with it.MethodsWe systematically searched four databases—MEDLINE/PubMed, EMBASE, SCOPUS, and CINAHL. We included studies where study participants were informal caregivers, their PU was assessed, and measurement tool was implicitly described. We excluded studies where study participants were paid caregivers.ResultsOut of the 2160 studies screened, we included 15 published between 2009 and 2023. The included studies measured caregivers' PU as limited estimated life expectancy, understanding that dementia is incurable and life‐limiting. Estimated life expectancy was the most common measure of PU among caregivers to PwDs. Across studies, around 90% of caregivers acknowledged dementia as incurable, while only about 40% acknowledged it as life‐limiting. Caregivers of PwDs who were sicker (acute medical problems or functional dependence) and those who had discussed goals of care with healthcare providers were more likely to have more accurate PU for PwDs. Caregivers' with better PU were more likely to state a preference for comfort‐focused care, and their PwDs were likely to receive fewer burdensome interventions and experience greater comfort during the dying process.ConclusionOur findings highlight the need for a comprehensive measure to assess the multifaceted nature of caregivers' PU, delve deeper into factors influencing caregivers' PU, and explore its impact on caregivers themselves.
Inflation Expectation Uncertainty in a New Keynesian Framework
Authors: FUEST ANGELA , SCHMIDT TORSTEN 
Published: October 2024

AbstractThis study analyzes inflation expectation uncertainty and the effect on economic activity. Within a New Keynesian framework, we estimate the effect of an inflation expectation uncertainty shock on the macroeconomy. Inflation expectation uncertainty negatively affects the inflation rate and the output gap, without having a distinct effect on the level of inflation expectations. Second, we provide a theoretical foundation for the effect of inflation expectation uncertainty in a New Keynesian‐type model, in which uncertainty affects economic activity via the supply side and the demand side of the economy. The results suggest that the demand channel outweighs the supply channel.
Familiarity Breeds Contagion∗
Authors: AGARWAL SUMIT , MURLIDHARAN ADITYA , NISHESH NAMAN , TANTRI PRASANNA 
Published: October 2024

AbstractAlthough the literature has studied the impact of social ties on credit markets, the possibility of social relations causing contagion remains unexplored. We study the Indian caste system and the group loan structure, where members screen and monitor each other. Using loan‐month level data provided by a nonbanking lender, we find that shocks take the form of a loan default contagion within local caste networks, plausibly due to preexisting economic linkages. Several robustness tests rule out delayed propagation of shocks being mischaracterized as a contagion. Thus, we highlight a dark side of social ties in credit markets.
Multicentric Retrospective Study on Safety and Efficacy of a Novel Injectable Poly‐l‐Lactic Acid for Buttocks Recontouring
Authors: Russo Paola Rosalba , Bovani Bruno , De Angelis Francesca , Forte Riccardo , Vercesi Franco , Salti Giovanni 
Published: October 2024

ABSTRACTBackgroundPoly‐l‐lactic acid (PLLA) injectables have gained increasing attention in aesthetic medicine due to their biocompatibility and long‐lasting effects. Although their primary application centers around facial rejuvenation, their potential for off‐label use in other body areas has been investigated, demonstrating promising outcomes in terms of both efficacy and safety.AimThis study aims to assess the safety and efficacy of a novel 630 mg PLLA‐based filler (GANA X), in buttocks treatment.MethodsSix physicians treated 51 patients for buttock aesthetic treatment across six different medical facilities in Italy. A survey was filled by both physicians and patients regarding treatment safety, efficacy, and change in quality of life.ResultsWe reported minor or mild adverse events, self‐resolving within the next few days. Both physicians and patients confirmed notable aesthetic improvements following treatment, varying from moderate to significant enhancement. These effects endured throughout follow‐up visits spanning up to 24 months. Patient‐reported outcomes indicated elevated self‐esteem and improved quality of life posttreatment.ConclusionsThe high level of satisfaction reported by both physicians and patients highlights the efficacy and tolerability of GANA X filler for buttocks treatment, encouraging their use and research for off‐label body areas.
Identification of Rust Resistance Genes in Wheat (Triticum aestivum L.) Using Molecular Markers and Host–Pathogen Interaction Tests
Authors: Pal Dharam , Kumar Subodh , Bhardwaj Subhash Chander , Gangwar Om Prakash , Pal Anjali , Patial Madhu , Watpade Santosh , Harikrishna  , Mallick Niharika , Fandade Vikas , Roy J. K. 
Published: October 2024

ABSTRACTThe leaf rust (Puccinia triticina f. sp. tritici), stripe rust (Puccinia striiformis f. sp. tritici), and stem rust (Puccinia graminis f. sp. tritici) are major fungal constraints affecting wheat production worldwide. Identifying and deploying wheat varieties with diverse resistance are the best ways to manage all the rusts. Therefore, a continuous search goes on to identify diverse germplasm with effective rust resistance that expresses at different stages of plant growth (seedling and adult plant). A set of 22 rust resistant wheat genotypes and 4 checks (controls), viz., Avocet‐Yr10, Avocet ‐Yr15, Agra Local, and respective positive checks were studied for characterising rust resistance genes using host–pathogen interactions complemented by molecular markers. Among 22 elite genotypes, 05 genotypes amplified 191 bp fragment with marker PSY1E1, confirmed the presence of gene Lr19/Sr25. These genotypes also expressed resistance to most virulent leaf rust pathotypes, 77‐5 and 77‐9 in host–pathogen interaction test (HPI). Seven genotypes showed the presence of Lr34/Yr18/Sr57/Pm38/Ltn1 in homozygous state, whereas G4 showed its presence in heterozygous condition. Among 22 genotypes, 16 genotypes possessed Yr10. Five genotypes (22.7%) exhibited two gene combinations, Lr19/Sr25, and Yr10 as revealed through the detection of 191 bp fragment with marker PSY1E1 and 260 bp fragment with co‐dominantly inherited microsatellite marker Xpsp3000, respectively. All five genotypes (G2, G3, G8, G9, and G18) also expressed brown glumes controlled by the gene Rg1 tightly linked to Yr10 on the 1BS chromosome. Broad spectrum rust resistance present in these lines in good agronomic backgrounds could be used as potent genetic donors for diverse and durable rust resistance breeding programmes in wheat.
Effects of temperature and light on early sporophyte development of Saccharina japonica and S. latissima (Phaeophyta)
Authors: Jung Jae Woo , Xing Qikun , Kim YoungWoo , Lee Na Young , Park Ji‐Sook , Yarish Charles , Lindell Scott , Heo Jin Suk , Kim Jang K. 
Published: October 2024

AbstractSaccharina japonica is common aquaculture species in Asia, whereas S. latissima is cultivated in North America and Europe. This study aims to select superior strains using breeding techniques for high‐temperature tolerance and faster development at the early sporophytic stage. Qualitative experiments were conducted to observe the reproduction and early development of sporophytes under different temperatures (5, 10, 15, and 20°C) and light conditions (5 and 40‐μmol photons m−2 s−1) for 20 days after male and female gametophytes were crossed. Two female (F05 and F15, S. japonica; FB and FO, S. latissima) and male (M06 and M14, S. japonica; MB and MO, S. latissima) gametophyte strains in each species were used. No inter‐specific crosses were made. Four possible intraspecific crosses were cultured. Regardless of the species, the development of sporophytes was observed earlier at 10°C than all other temperatures (5, 15, and 20°C). No sporophytes were observed at 20°C during the experiment. The crosses of F15xM14 (S. japonica) and FBxMB (S. latissima) showed higher thermal tolerance and rapid development of sporophytes than other crosses. These results suggest that optimal reproduction and early development of sporophytes can vary from species to species of the same genus and even between strains of the same species.
The effectiveness of cognitive linguistics‐inspired language pedagogies: A systematic review
Authors: Liu Dilin , Qin Jie 
Published: October 2024

AbstractThis systematic review synthesizes the literature (involving 62 empirical studies) regarding the effectiveness of cognitive linguistics‐inspired language pedagogies (CL‐ILPs) on second language (L2) learning. It begins with an overview of the main theoretical tenets of cognitive linguistics followed by a description of the data selection, coding, and analysis. Then, besides noting a sharp increase of research on CL‐ILPs in the past 20 years, the review presents four main findings: (a) While various language features have been taught in CL‐ILPs, the teaching targets of CL‐ILPs have been mainly low‐schematic constructions, such as phrasal verbs and prepositions, but a few recent studies have explored the teaching of clause‐ or sentence‐level structures including conditional clauses, (b) conceptual metaphor, cognitive grammar, construction grammar, and cognitive semantics have been the main guiding cognitive linguistics theories applied in language teaching, and the hallmark teaching practices of CL‐ILPs include the use of technology‐supported or technology‐delivered visuals, schemas, and diagrams; embodied activities; and group and/or pair work, (c) methodologies used in CL‐ILP research have become increasingly sophisticated, and (d) CL‐ILPs have been found to be effective in 93.5% (i.e., 58) of the 62 reviewed studies covering learners of different age groups, first languages, and learning contexts. These findings are discussed to uncover insights concerning CL‐ILP research. Pedagogical implications and future research directions are also discussed.
Emergency medical supply planning considering prepositioning and dynamic in‐kind donation management in healthcare coalitions
Authors: Wang Qingyi , Zhang Renshan , Luo Li 
Published: October 2024

AbstractThis study tackles an integrated emergency medical supply planning problem, which incorporates supply prepositioning and dynamic in‐kind donation management in healthcare coalitions. Although this problem is vital for field practice, it is not investigated in the existing emergency supply planning literature. To fill the gap, we propose a two‐stage stochastic programming model, which facilitates the planning of emergency medical supply prepositioning before disasters and dynamic supply transshipment and in‐kind donation solicitation and distribution after disasters. With a case study on the healthcare coalition of West China Hospital in Sichuan Province of China under the background of the COVID‐19 epidemic, the proposed model and seven comparison models are optimally solved to show the effectiveness and benefits of our model. We conduct sensitivity analysis to generate managerial insights and policy suggestions for better emergency medical supply management practices in healthcare coalitions.
Mandibular bone imaging assessment in thalassemia – a systematic review
Authors: da Silva Larissa Conrado , Marques Pedro Albuquerque Counago , Oliveira dos Santos Bruna Cristina , Cruz Thalyta Cristina Souza da Silva , de Andrade Bruno Augusto Benevenuto , Ortega Karem L. , Munhoz Luciana , Tenório Jefferson R. 
Published: October 2024

AbstractObjectiveThis systematic review aimed to verify if individuals with thalassemia present changes in radiomorphometric indices and fractal analysis that can be accessed using panoramic radiographs.Material and methodsObservational studies that evaluated cortical and trabecular bone patterns in dental routine radiographs were selected from six bibliographic databases. Risk of bias was analyzed using the Joanna Briggs Institute Critical Appraisal Checklists. Quality of evidence was verified using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.ResultsTwo hundred three studies were initially retrieved from databases. Three cross‐sectional studies, encompassing a total of 129 thalassemic patients, were deemed eligible after applying the inclusion criteria. Bone mineral density (BMD) evaluations were performed using panoramic radiographs and considered the following radiomorphometric indexes: mandibular cortical index (MCI), mandibular cortical width (MCW), panoramic mandibular index (PMI). Fractal dimension analysis (FDA) and simple visual estimation (SVE) were also employed. Overall, FDA and MCW from thalassemia individuals were lower than controls.ConclusionFDA and MCW are frequently altered in patients with thalassemia and may be employed as screening tools for reduced BMD. However, the certainty of evidence for this outcome was very low, mainly due to methodological flaws.
Revisiting the sequence symmetry analysis design
Authors: Madsen Jeppe Ekstrand Halkjær 
Published: October 2024

AbstractThe purpose of this paper is to re‐examine the sequence symmetry analysis (SSA) in a mathematical framework to improve the understanding and use of the design. The mathematical properties of the crude, null‐effects, and adjusted sequence ratios (SR) are analyzed in the presence of prescription time‐trends and unmeasured time‐invariant confounding. The theoretical results are illustrated in a simulation study. The crude SR can be interpreted as an estimator of the hazard ratio (HR) of treatment when the allowed time between initiation of the treatment and the outcome drug is small. The HR can easily be estimated flexibly as a function of covariates, such as age and sex, using logistic regression. The crude SR implicitly adjusts for unmeasured time‐invariant confounding, whereas the null‐effects SR, and thereby the adjusted SR, make little sense unless treatment and outcome are strictly independent. The use of the adjusted SR should be abandoned. Another design should be used if it is infeasible to require treatment and outcome sufficiently close. The crude SR can be modeled flexibly with logistic regression to estimate covariate‐dependent HRs or at least to test whether the HR depends on covariates.
Macroevolutionary trends and diversification dynamics in the hindgut order Clevelandellida (Ciliophora, Armophorea)
Authors: Pecina Lukáš , Rurik Ivan , Vďačný Peter 
Published: October 2024

AbstractClevelandellids are highly diversified and widespread unicellular eukaryotic organisms inhabiting the digestive tract of a broad spectrum of invertebrates and vertebrates. Time‐calibrated phylogeny of clevelandellids was built to reconstruct their ancestral hosts using stochastic mapping, investigate their coevolution with animal hosts using an event‐based tree reconciliation approach and examine the impact of hosts on their diversification dynamics and molecular evolution using the MuSSE method and phylogenetic regression. The progenitor of the analysed representatives of the order Clevelandellida colonized the hindgut of anurans in the Late Jurassic. Later on, clevelandellids switched from anuran to other terrestrial poikilotherm vertebrate and invertebrate hosts. Panesthiine cockroaches served as a source for at least four independent colonization waves into millipedes and non‐panesthiine cockroaches. Duplication events, duplications followed by host switching and inertia were recognized as the most relevant coevolutionary processes shaping the common history of clevelandellids and their animal hosts over geological time. Clevelandellids associated with panesthiine cockroaches were revealed to have significantly higher net‐diversification rates than ciliates living in millipedes, non‐panesthiine cockroaches and poikilotherm vertebrates. Clevelandellids show some interesting macroevolutionary trends, including clustering specific for higher taxa of their hosts, no backward transfers from invertebrate to vertebrate hosts and host‐dependent diversification dynamics.
Hybrid Surrogate Modeling Approach for Data Reduction and Design Space Exploration of Turbine Blades
Authors: Ali Sazeed S. , Yadav Vikas S. , Nouri Behnam , Ghani Abdulla 
Published: October 2024

Abstract
The conventional iterative optimization of turbine blades using computer-aided engineering simulations is resource-intensive, with high costs and time demands, as well as significant challenges in computational requirements and data management. The three-dimensional (3D) simulation data generated from computational fluid dynamics (CFD) and finite element analysis (FEA) for various blade geometries can range from hundreds of gigabytes to multiple terabytes, complicating long-term storage and access. To address this, we propose a machine learning-based methodology for data reduction and prediction of 3D surface field data. Our approach involves developing a convolutional variational auto-encoder (VAE), consisting of an encoder and a decoder. The encoder compresses the input data into a representation of reduced dimensionality in a latent space, while the decoder reconstructs the data from this latent space back to its original form. This significantly reduces the amount of stored data, facilitating long-term use. Additionally, we train a fully connected feedforward multilayer perceptron (MLP) to map geometry parameters, which generate blade variations, to the latent space. By combining the MLP with the VAE's trained decoder, we create our proposed multilayer perceptron–variational auto-encoder (MLP–VAE) hybrid model capable of predicting surface field data for new, unseen blade geometries. The MLP–VAE generates latent representations and surface field results with high accuracy (&gt;97%) and without additional computational costs, offering a highly efficient and scalable solution for turbine blade optimization.