bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phosphate Fertilization Improve Productivity and Chemical-Bromatological Composition of Leaf Blade of Unburned Pasture
Authors: Silva Luiz Carlos da , Almeida Lobo Francisco de 
Published: October 2024

Objective: We evaluate the effects of phosphate fertilization on the leaf blade productivity of unburned Brachiaria brizantha, cv. Marandu, as well its chemical-bromatological composition compared to the pasture burning in the southwestern Amazon.

Theoretical Framework: Brazilian Amazon has one of the highest proportion of planted pastures in Brazil and the Brachiaria brizantha is the most used species. The burning is an important factor that lead to the gradual degradation of pastures. These circumstances generate pastures with low capability of providing feed for cattle farming. The improvement caused by burnings occurs only in short periods after burning. Some alternative sources with a low content of soluble P, in turn, increases biomass productivity and the nutritional value of cultivated species.

Method: A field experiment was carried out in a completely randomized blocks design. The treatments consisted of unburned pasture treated with 0, 25, 100 and 200 kg ha-1 of P compared to the pasture burning. After applying the treatments, the pasture was desiccated in order to homogenize the plant emergence and growth after the period without rain from July to September.

Results and Discussion: The dose of 100 kg ha-1 of P for unburned pasture promoted better productivity and mineral nutrient concentrations, and leaf quality for animal consumption was improved. Values of acid detergent fiber, neutral detergent fiber, lignin and crude protein indicate an adequate bromatological composition of leaf for animal consumption at 56 days of growth.

Research Implications: The practical and theoretical implications of this research are discussed, providing insights into how the results can be applied or influence practices in the field of pasture management without fire using. These implications could encompass on how to apply and how much of an alternative phosphate must be applied to the soil to supply phosphorus for B. brizantha instead of using fire in the pasture management.

Originality/Value: This study contributes to the literature by highlighting the superiority of phosphorus application from alternative source allied to N and K fertilization compared to the pasture burning practice in the Southwestern Amazon. This innovative approach can be used as a base for new researches and applied in the level of cattle farmers.
PENERAPAN SAHAM SERI A DWI WARNA PADA HOLDING BUMN PUPUK
Authors: MUNINGGAR RORO AJENG 
Published: October 2024

The purpose of this scientific research is to analyze the implementation of Article 2A paragraph (2) of Government Regulation Number 72/2016 concerning the obligation for the State of Indonesia, especially to have special shares in subsidiaries of former SOEs. The State of the Republic of Indonesia c.q the Ministry of SOEs followed up PP 72/2016 by issuing a letter to the Fertilizer SOE Holding to assign shares with privileges to PT PKT, PT PKG, PT PKC, and PT PIM. The establishment of the Fertilizer SOE Holding itself was carried out based on PP 28/1997 and PP 54/2011. The normative research method uses the law as a source of approach and research material to obtain conclusions that are carried out with the deductive method. The results of this study explain that the transfer of the same owned by the State of the Republic of Indonesia to PT PKT, PT PKG, PT PKC, and PT PIM to the Fertilizer SOE Holding was carried out before the enactment of PP 2/2016 which took effect on the date of promulgation on December 31, 2016. Based on this, PT PKT, PT PKG, PT PKC, and PT PIM have no obligation to issue Series A Dwi Warna Shares as per Article 2A paragraph (2) PP 72/2016. This obligation applies to ex-BUMN companies whose transfer of shares of the State of Indonesia to SOEs occurs after the entry into force and promulgation of PP 72/2016. Also included is PT PSP which is an ex-spin off company
Fatores de risco cardiovasculares após infarto agudo do miocárdio em uma cidade do estado de Minas Gerais
Authors: Flora Giovana dos Santos , Bendia Heuller Alexandre Marteline , Veiga Aline Alves da , Silva Jaqueline  Miranda Pena da , Reis Cristiano Mendes dos , Silva Gustavo Henrique de Melo da , Silva Márcia Giovane Rodrigues da , Silva Eveline Cristina da , Silva Juliana Santiago da 
Published: October 2024

Objetivo: Identificar os principais fatores de risco cardiovasculares que permanecem na vida dos pacientes com diagnóstico de Infarto Agudo do Miocárdio (IAM). Métodos: Trata-se de um estudo observacional do tipo transversal, com caráter descritivo e exploratório, incluindo análise quantitativa. Os dados foram levantados por meio da entrevista de 50 pacientes do ambulatório de cardiologia em uma cidade de Minas Gerais, no período de novembro de 2020 a fevereiro de 2021. Resultados: Dos entrevistados, 100% apresentaram algum fator de risco cardiovascular avaliado, tendo como resultados relevantes o aumento do índice de massa corporal, tabagismo, estresse e consumo de alimentos ricos em gorduras e açúcar, alta prevalência de hipertensão arterial e diabetes mellitus, além da maioria dos entrevistados apresentarem conhecimento acerca dos fatores de risco cardiovasculares. Conclusão: Faltam medidas preventivas na rotina dos entrevistados, e esta é essencial para evitar os riscos, buscar uma melhor qualidade de vida e evitar a recorrência de IAM.
Activities of Human Rights Organizations to Protect the Rights of Citizens in the Field of Receiving Services in Microfinance Organizations
Authors: Свистунов С.В. 
Published: October 2024

Актуальность темы исследования обусловлена необходимостью развития и совершенствования деятельности правозащитных организаций по защите прав граждан в сфере получения услуг в микрофинансовых организациях в Российской Федерации. В среде общественных объединений в рамках ассоциаций, союзов, деятельность которых частично связана с защитой прав граждан в сфере получения потребительских краткосрочных займов в микрофинансовых организациях, работа по оказанию юридической помощи носит формальный характер, что вызывает обоснованное недоверие со стороны граждан. Это связано, в том числе, с низким уровнем информированности граждан в регионах о возможности получения такой помощи, отсутствием централизованной информатизации, недооценкой эффективности участия общественных организаций в осуществлении работы по защите прав граждан в сфере получения услуг в микрофинансовых организациях. Целью исследования является совершенствование деятельности правозащитных организаций по защите прав граждан в сфере получения потребительских (краткосрочных) займов в микрофинансовых организациях. Во исполнение поставленной цели автор наметил ряд задач: определить направление деятельности общественных организаций в этой области, их потенциал; определить характер мер для эффективной работы правозащитных организаций, осуществляющих защиту прав граждан в сфере получения потребительских (краткосрочных) займов в микрофинансовых организациях.
The relevance of the topic raised is formulated by the need to develop and improve the activities of human rights organizations to protect the rights of citizens in the field of receiving services in microfinance organizations in the Russian Federation. Among public associations within associations, unions, whose activities are partly related to the protection of the rights of citizens in the field of obtaining consumer short-term loans from microfinance organizations, the work of providing legal assistance is of a formal nature, which causes justified mistrust on the part of citizens. This is due, among other things, to the low level of awareness of citizens in the regions about the possibility of receiving such assistance, the lack of centralized informatization, and underestimation of the effectiveness of the participation of public organizations in the implementation of work to protect the rights of citizens in the field of receiving services in microfinance organizations. The purpose of the study is to improve the activities of human rights organizations to protect the rights of citizens in the field of obtaining consumer (short-term) loans from microfinance organizations. In order to fulfill this goal, the author outlined a number of tasks: to determine the direction of activity of public organizations in this area, their potential; determine the nature of measures for the effective work of human rights organizations, protecting the rights of citizens in the field of obtaining consumer (short-term) loans in microfinance organizations.
From the Decree of the President of the Russian Federation dated November 9, 2022 No. 809 "On Approval of the Fundamentals of State Policy for the Preservation and Strengthening of Traditional Russian Spiritual and Moral Values" to the Federal Law of the Same Name?
Authors: Мохов А.А. 
Published: October 2024

Важнейшему документу стратегического планирования — Указу Президента РФ от 9 ноября 2022 г. № 809 — исполняется два года. Его отправные положения используются также при разработке других документов. Однако в плане практической реализации его положений имеется ряд практических трудностей. Успешная реализация положений этого документа требует внесения ряда изменений и дополнений в законодательство. Одним из векторов развития законодательства в контексте сохранения и укрепления традиционных российских духовно-нравственных ценностей может стать одноименный федеральный закон.
The most important strategic planning document, as Decree of the President of the Russian Federation No. 809 dated November 9, 2022, turns two years old. Its starting points are also used in the development of other documents. However, there are a number of practical difficulties in the practical implementation of its provisions. The successful implementation of the provisions of this document requires a number of amendments and additions to the legislation. The federal law of the same name may become one of the vectors of legislative development in the context of preserving and strengthening traditional Russian spiritual and moral values.
Pengaruh Disiplin Kerja, Pengalaman Kerja, dan Komitmen Organisasi Terhadap Kinerja Karyawan Pada PT Al-Shofa Duta Mandiri
Authors: Latifa Najwa , Agusdin Agusdin , Suryatni Mukmin 
Published: October 2024

This study aims to determine the Influence of Work Discipline (X1), Work Experience (X2), and Organizational Commitment (X3) on Employee Performance at PT Al-Shofa Duta Mandiri Mataram. The type of research used is causal associative research. The technical analysis used is Multiple Linear Regression using SPSS. In this study, a sample determination technique was used by the saturated sampling method or census, so that the respondents in this study were all employees of PT-Al-Shofa Duta Mandiri Mataram totaling 50 employees. The results of the analysis showed that: (1) Work Discipline had a positive and significant effect on Employee Performance at PT-Al-Shofa Duta Mandiri Mataram (2) Work Experience had a positive and significant effect on Employee Performance at PT-Al-Shofa Duta Mandiri Mataram (3) Organizational Commitment had a positive and significant effect on Employee Performance at PT-Al-Shofa Duta Mandiri Mataram. With the presentation of the results of the analysis above, the company can pay more attention to the environment around the workplace, the company must be able to overcome the problems around the workplace so that employees are comfortable working, then can increase work activities in the team as well as an assessment of employee attitudes and free employees to innovate so that employees feel recognized and still maintain a state where employees can enjoy all existing infrastructure, With the help of infrastructure, employees will find it easier to complete tasks, all of which are done to improve employee performance.
Reduction in the level of dehydroepiandrosterone as an indicator of stress-associated reproductive health disorders. Review
Authors: Semenyuk L. M. , Yuzvenko T. Y. , Kozachuk Y. S. , Zahorodnya O. S. 
Published: October 2024

The issue of changes in reproductive steroidogenesis in women of childbearing age arises from disruptions in the ovarian‑menstrual cycle and their consequences (e.g., infertility, miscarriage, premature delivery, decreased libido, and signs of sexual dysfunction). The war in Ukraine has exacerbated the existing demographic crisis, highlighting the strategic importance of reproduction for the country. Under the conditions of martial law, the stress level in the human body increases, leading to an increase in cortisol levels. The relationship between stress and increased cortisol levels and women’s reproductive function has been sufficiently studied. However, the problem of the correlation between stress, hypercortisolemia, and changes in the level of dehydroepiandrosterone (DHEA), as a precursor of steroidogenesis, and the reproductive function of women remains under active investigation. DHEA is considered a precursor to the production of sex hormones (testosterone, estrogen, progesterone), but it is also produced in greater amounts as a moderator of the stress response. Researchers studying the effects of DHEA on the human body note that the ratio of DHEA to cortisol has been associated with increased stress resistance: with DHEA levels higher than cortisol levels, stress resistance increases, and women experience fewer negative consequences from the same stressors compared to individuals with a lower DHEA/cortisol ratio. Researchers of menstrual function in teenagers have reached similar conclusions. When reviewing recent papers on the value of DHEA levels for ovarian reserve, we found numerous studies reporting improvements in IVF outcomes in women with low follicular reserves. It is to the works of reproductive scientists that we owe information about the positive role of pro‑androgenic steroids in improving fertility, especially in the context of using androgens in ovulation stimulation protocols. Taking into account all of the above, we consider the use of DHEA in the pre‑gravid stage to be promising for women with hypoandrogenism, stress‑related menstrual disorders, and functionally increased cortisol levels.
Postoperative hypoparathyroidism: relevance, prevention, treatment. Review
Authors: Shidlovsky V. O. , Shidlovsky O. V. , Morozovich I. I. , Privrotskyi V. M. 
Published: October 2024

The aim of this article is to review the main aspects of postoperative hypoparathyroidism, causes and mechanisms of development, prevention, treatment, its results and consequences. Postoperative hypoparathyroidism is a frequent complication of operations on the thyroid gland. It reduces the quality of life of patients, and in some cases leads to disability and death. An analysis of the methods for preventing intraoperative injuries of the parathyroid glands, prevention of postoperative hypoparathyroidism and their assessment by various authors was carried out. Attention is drawn to the fact that uncontrolled drug therapy of postoperative hypoparathyroidism has several side effects that cause the development of complications in the functioning of organs and systems of the body: hearing, vision, cardiovascular, nervous and urinary systems, musculoskeletal system, gastrointestinal tract. Impaired quality of life, significantly impacting physical, mental, or emotional health, has been documented in many studies using standardized instruments validated for chronic illness. Therefore, the prevention and reduction of the permanent form of this complication is of particular importance and relevance. It should be noted that scientific interest in the problem of postoperative hypoparathyroidism is supported by the contradictory results of research by modern authors, especially regarding the prevention of the development of functional insufficiency of the parathyroid glands. Summarizing the considered publications devoted to postoperative hypoparathyroidism in thyroid surgery, it is worth emphasizing that the problem remains relevant and not fully resolved. The risks of postoperative hypoparathyroidism can be divided into factors related to the patient (polymorbidity, vitamin D deficiency, female gender, young age), as well as to the disease that became an indication for surgery (goiter, progressive malignant tumor, hyperthyroidism, autoimmune thyroiditis), and with surgical intervention (volume of surgical intervention, repeated operations, experience of the surgeon).
Gastrointestinal effects of incretin hormone receptor agonists
Authors: Tkach S. M. , Tretyak O. E. , Dogotar V. B. 
Published: October 2024

Agonists of incretin receptors (AIRs), such as glucagon‑like peptide‑1 (GLP‑1) and glucose‑dependent insulinotropic peptide (GIP), are widely used in the complex treatment of type 2 diabetes mellitus (T2DM) and obesity worldwide. To date, there are 7 AIRs approved by the FDA and available for clinical use. The effect of these drugs on the gastrointestinal tract (GI) and the liver is significant and has significance in the clinical practice of gastroenterology and hepatology. Widespread use of this class of drugs has shown that, while effective in treating T2DM, obesity, and metabolic‑associated steatotic liver disease (MASLD), they also have undesirable side effects, most often gastrointestinal, such as nausea, vomiting, diarrhea, and constipation. These side effects, commonly associated with delayed gastric emptying, may decrease their significant benefits in the treatment of T2DM, reduce body weight and improve cardiometabolic status, and may become a barrier to their use at higher doses. In many studies, these side effects are dose‑dependent, most of them are observed during dose escalation, and they tend to improve with continued use, although the mechanisms of this improvement are still unclear. Recent concerns also relate to the risks of using GLP‑1 receptor agonists in perioperative patient management, given that increased residual gastric content in patients treated with ARI increases the risk of aspiration in these patients. Therefore, when using short‑acting ARIs, it is not recommended to take them on the day of surgery, and when using long‑acting drugs, discontinue their use at least 7 days before surgery, or even earlier if necessary. Many other ARIs are expected to be approved soon and will enter the therapeutic armamentarium.
Oncocytic cells in the punctate of a thyroid gland nodule. Is there a reason to suspect cancer
Authors: Palamarchuk V. O. , Smolovik N. V. , Kuts N. V. , Tovkai O. A. 
Published: October 2024

Oncocytic metaplasia can occur in various thyroid conditions. Individual cells, follicles, or groups of follicles may show signs of oncocytic metaplasia, such as in irradiated thyroid gland, nodular goiter, and chronic lymphocytic thyroiditis, as well as in long‑term autoimmune hyperthyroidism (Graves’ disease). Malignant nodes from oncocytic cells are even rarer. According to the world literature, the prevalence of oncocytic carcinoma (OC) among all thyroid cancers is from 3% to 5%. Among nodes that had oncocytic cells in the cytological sample, oncocytic carcinoma is detected in 5.0—49.1% of cases; and the overall prevalence of malignancy among such nodes (including papillary and follicular cancer, oncocytic variant and OC) is 35.8%.
Objective — to establish a connection between the presence of oncocytes in punctate thyroid nodules and the detection of cancer on histopathological examination; to investigate the possibility of using the presence of oncocytes in the punctate as a predictor of the presence of cancer.
Materials and methods. A monocentric retrospective study was conducted involving 487 patients who underwent primary surgery between January 2019 and December 2023 for nodular and multinodular goiter (TBSRTC III, IV, V). All patients underwent thyroidectomy or hemithyroidectomy, supplemented with neck dissection and lymphadenectomy.
Results. Among 487 patients with thyroid nodules categorized as Bethesda III, IV, or V, malignancy was identified in 211 cases. Of these, 36 patients exhibited oncocytic changes in the punctate, while 175 patients did not. In the remaining 276 patients, cancer was not diagnosed, including 60 cases with detected oncocytic cells and 216 cases without such changes on cytological examination. The data were analyzed for each patient group according to the Bethesda classification. The highest test performance (specificity and overall efficiency) was observed in patients with Bethesda III, though sensitivity was zero. Similarly, in patients with Bethesda IV and V, sensitivity remained extremely low, resulting in low overall efficiency despite high specificity.
Conclusions. The study did not establish a significant relationship between the presence of oncocytic cells in punctate thyroid nodules (Bethesda III, IV, V) and the subsequent diagnosis of thyroid cancer. Therefore, the presence of oncocytic cells in thyroid nodules cannot be considered a reliable predictor of malignancy. Additionally, the presence of oncocytes does not appear to be a negative prognostic factor for malignancy compared to their absence.
Quality of life assessment with SIBDQ in children with upper gastrointestinal pathology
Authors: Shlieienkova H. O. , Tsiura O. M. , Voloshyn K. V. , Pavlenko N. V. , Voloshyna L. H. , Slobodianiuk O. L. , Muzyka O. O. 
Published: October 2024

Functional and organic diseases of the digestive system today occupy one of the leading places in the structure of somatic pathology of childhood and adolescence and negatively impact young patients’ quality of life. Among the gastrointestinal tract diseases, the first place is occupied by the pathology of the gastroduodenal zone in children. Gastrointestinal diseases rarely occur in isolation in the form of damage to only the upper or lower parts of the digestive system, especially in childhood. Therefore, in the presence of dysfunction symptoms and pathological changes in the upper gastrointestinal tract, it is advisable to use non‑invasive means to diagnose pathological changes in the lower gastrointestinal tract.
Objective — to analyze the quality of life using the Short Inflammatory Bowel Disease Questionnaire (SIBDQ) in children and adolescents with upper gastrointestinal tract pathologies.
Materials and methods. The study involved 174 children who visited the Kharkiv city children’s clinical hospital No 19 with complaints about upper gastrointestinal disorders (7—18 years old). Patients were interviewed using the self‑reported inflammatory bowel disease quality of life questionnaire SIBDQ, which assesses physical, social and emotional well‑being (the result is determined from 10 to 70 points, where 10 is the worst condition).
Results. The median SIBDQ score for the entire sample was 51 points [Q1; Q3: 45; 58], with 47.1±3.7% of respondents having up to 50 points. In girls, the median was significantly lower than in boys — 49 [40; 55] versus 55 [49.0; 65.5] (pU=0.05). According to the nature of the endoscopic picture, 55% of children with gastroesophageal and duodenogastric reflux, 38.6% of children with erythematous duodenopathy, 45.9% of children with erosive and ulcerative changes and 61.5% of patients with esophagitis had a low SIBDQ score. Boys with low SIBDQ scores were more prone to gastroesophageal and duodenogastric reflux. All other endoscopic changes were significantly more common (p <0.05) in girls with less than 50 points according to the survey results.
Conclusions. In 47% of children with complaints of upper gastrointestinal dysfunction, the quality of life score was low by the SIBDQ (< 50). The median SIBDQ score in girls was significantly lower than in boys: 49 [40; 55] versus 55 [49.0; 65.5] points (pU=0.05), respectively. Girls with instrumentally confirmed esophagitis had significantly lower SIBDQ scores compared to boys with esophagitis and girls with other gastrointestinal disorders — 41.5 [37; 46] (p <0.05). The use of the SIBDQ questionnaires in school‑age children and adolescents is advisable not only for lower gastrointestinal tract diseases but also for gastroduodenal zone diseases.