bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Sociologia de Michel Maffesoli e a Gestão Social: gerencie-me ou te devoro
Authors: Pacifico Filho Miguel , Cançado Airton Cardoso , Borges Thelma Pontes 
Published: January 2016

Este trabalho tem o objetivo de aproximar dois referenciais: de um lado, a sociologia de Maffesoli e sua análise da contemporaneidade por meio da relativização de pressupostos sociológicos e filosóficos acerca da realização plena da humanidade em projetos ancorados em um devir e, de outro, a Gestão Social, que se apresenta como proponente de práticas alternativas ao pensamento administrativo tradicional, centrado na racionalidade utilitária. A partir da metodologia de análise comparativa, demonstram-se proposições-chave na obra de Maffesoli, politeísmo popular e socialidade, relacionando-os com a Gestão Social e suas discussões em torno da dialética negativa, o interesse bem compreendido e a esfera pública. Concluiu-se que a Gestão Social se propõe a equacionar questões da contemporaneidade apontadas pela sociologia maffesoliana e que esta pode oferecer àquela os elementos para que se posicione como uma gestão para o que é, para o presente, e não somente para o que deve ser, para um futuro distante e impreciso.
Pre-clinical Evaluation of an Adult Extracoproreal Carbon Dioxide Removal System for Pediatric Application
Authors: Mussin Yerbol , Jeffries Richard , Bulanin Denis , Zhumadilov Zhaksybay , Olzhayev Farkhad , Federspiel William 
Published: January 2016

Introduction. Adult extracorporeal carbon dioxide removal (ECCO2R) systems and pediatric ECMO share the common objectives of having a low blood flow rate and low priming volume while safely maintaining sufficient respiratory support. The Hemolung is a highly simplified adult ECCO2R system intended for partial respiratory support in adult patients with acute hypercapnic respiratory failure. The objective of this work was to conduct pre-clinical feasibility studies to determine if a highly efficient, active-mixing, adult ECCO2R system can safely be translated to the pediatric population. Methods. 14 healthy nonsedated juvenile sheep were used for acute (2 animals) and 7-day chronic (12 animals) in-vivo studies to evaluate treatment safety independently of respiratory related injuries. In all evaluations, we hypothesized that gas exchange capabilities of the Hemolung RAS in this model would be equivalent to the adult configuration performance at similar blood flows - minimum CO2 removal of 50 mL/min at a venous partial pressure of CO2 equal to 45 mmHg. Target blood flow rates were set to a minimum of 280 mL/min. Swan Ganz catheters were used under general anesthesia in the two acute subjects to evaluate blood gas status in the pulmonary artery.Results. The Hemolung RAS was found to have adequate gas exchange and pumping capabilities for full respiratory support for subjects weighing 3 – 25 kg. The Hemolung device was estimated to provide a partial respiratory support for subjects weighing 27 – 34 kg. The seven-day studies in juvenile sheep demonstrated that veno-venous extracorporeal support could be provided safely at low flows with no significant adverse reactions related to device operation.Conclusion. The study outcomes suggest the potential use of the Hemolung RAS in a veno-venous pediatric configuration to safely provide respiratory support utilizing a significantly less complex system than traditional pediatric ECMO.
Un balance de la modernización autonómica y las tensiones intergubernamentales
Authors: Abellán López María Ángeles 
Published: January 2016

En este artículo se propone una visión panorámica de la modernización de las administraciones autonómicas desde su creación hasta la actualidad, en el marco de las relaciones intergubernamentales, sin ánimo de exhaustividad. Diferenciamos, grosso modo, cuatro ciclos modernizadores: el primero se identifica con la búsqueda de legitimidad y supervivencia de las administraciones autonómicas. El segundo se inspira en la Nueva Gestión Pública (NGP) y la irrupción de un paradigma postburocrático que posibilita el desarrollo de nuevas metodologías. El tercer ciclo modernizador se caracteriza por la primacía de la e-administración y la calidad de los servicios públicos. Finalmente, el último ciclo plantea tendencias antagónicas, según su ubiquen antes o después del estallido de la actual crisis económica.
The Integrated Life Cycle Assessment and Optimization Approach for Automotive De-manufacturing Systems
Authors: Alsaadi Naif , Franchetti Matthew 
Published: January 2016

<p class="jbls"><span lang="EN-GB">The Automotive Recycling Industry is addressing one of the biggest problems that the environment can face, the reuse and recycling of End-of-Life Vehicles (ELV). Improper disposal of wastes can create a big problem to the environment. The purpose of this paper is to use the Integrated </span><span lang="EN-GB">Life-Cycle Assessment (LCA) </span><span lang="EN-GB"> and Optimization Approach for Automotive De-manufacturing Systems with the aim of to finding out the most efficient and effective method that can be used to improve global ELV recycling. The United Nations Environment Program (UNEP) defines life cycle assessment is a tool that is used for systematic evaluation of the environmental aspects of either a product or service system in the entire stages of its lifecycle. In this research, second hand material research would be used to determine the current methods used for the disposal of the ELVs. Moreover, cost metrics will be used to determine the economic value of the network. This research will look into study background, the problem statement, hypothesis of the study, objectives of the study, literature review and methodology to outline possible research criteria to draw conclusion on the research topic. The research will be very resourceful to the scientific community because it will help to find the optimal location for the centralized processing facility that will minimize cost and avoid hazard in the environment. </span></p>
An assessment of patients’ knowledge of osteoporosis in Qatar: A pilot study
Authors: Hammoudeh Samer , Abdelrahman Magdi Hassan , Chandra Prem , Hammoudeh Mohammed 
Published: January 2016

Osteoporosis is a disease that affects the bones. It leads to increased risk of fractures as a result of decreased bone mineral density. The goal of this study was to assess the general perception of osteoporosis as well as knowledge of lifestyle, risk factors, and preventive measures among patients in Qatar. The study was conducted between September 2013 and September 2014. The study subjects (n = 93) were patients diagnosed with osteoporosis who attended the Outpatient Rheumatology Clinic at Hamad General Hospital in Doha, Qatar. The results showed that those with a university or graduate degree had a significantly higher level of knowledge about osteoporosis (p = 0.009) than those with less education. Among those in our study, knowledge related to osteoporosis was principally obtained through media sources such as television and radio (39%). In conclusion, osteoporosis patients in Qatar need a better understanding of the disease. Identifying thought patterns related to the perception of osteoporosis and treatment might assist in building a foundation for management modalities and effective preventive strategies for the disease in Qatar.
Association of erythrocytes antioxidant enzymes and their cofactors with markers of oxidative stress in patients with sickle cell anemia
Authors: Al-Naama Lamia M. , Hassan Mea'ad K. , Mehdi Jawad K. 
Published: January 2016

Background:Sickle cell anemia (SCA) is an inherited blood disease with known complications as a result of certain pathophysiological dysfunctions. It has been suggested that an increase in oxidative stress contributes to the incidence of these changes.Objectives:This study investigated the oxidant/antioxidant status of patients with SCA, and evaluated the effect of SCA on antioxidant enzymes and their cofactors.Methods:The study included 42 patients with SCA (in steady state), and a control group of 50 age-matched individuals without SCA. Serum malondialdehyde (MDA), copper, zinc, ferritin and iron levels, red blood cell (RBC) superoxide dismutase (SOD) and catalase levels were measured for the SCA and control groups.Results:Significantly lower levels of antioxidant enzymes (RBC SOD and catalase) and higher serum MDA levels (biomarker of oxidative stress) were found in SCA patients compared to the control group (all p < 0.001). Increased levels of serum ferritin, iron and copper and decreased zinc concentrations were also found in the SCA patients compared to the control group (all p < 0.001). In the SCA group, there were significant negative correlations between MDA levels and RBC SOD, RBC catalase, and serum zinc levels (p < 0.01), while a significant positive correlation between MDA with serum copper and iron levels (p < 0.01) was observed.Conclusion:SCA is associated with alterations in markers of oxidative stress including an increased MDA level, decreased antioxidant enzyme levels, and altered levels of enzyme cofactors (zinc, copper, and iron). This suggests that these antioxidant enzymes could be used as effective therapeutic targets for the treatment of this disease and supplementation of patients with substances with antioxidant properties may reduce the complications of this disease.
VÝVOJ PŮD NA OPUŠTĚNÝCH HALDÁCH PO TĚŽBĚ POLYMETALICKÝCH RUD NA HAVLÍČSKOBRODSKU
Authors: Brádlová Alexandra , Ivanov Martin , Buriánek David 
Published: January 2016

Old slags situated in the areas of former exploitation of polymetallic ore mineralization are places where initial steps of soil evolution in specific conditions can be investigated. Two soil profi les of different age have been studied in the Utín (2nd half of 13th century to 1st half of the 14th century) and Dlouhá Ves (60’s of 20th century) localities. Soil samples of fine fraction were studied including vertical distribution of selected elements (Fe, Pb, As, Ag, Cu; AAS) in context to other soil parameters including loss on ignition (LOI), sequential extraction analysis (SEA), soil exchangeable acidity (pH/KCl), mass specific (χ) and frequency dependent (χFD) magnetic susceptibility. There were higher concentration of Pb (up to 4,700 ppm), Cu and Ag (both up to 100 ppm) in the Utín soils observed mostly in upper part of the soil profile. Arsenic contamination occurs in entire soil profile with average concentration about 3,000 ppm. In the Dlouhá Ves soils, the higher concentrations of Ag, Cu (about 500 ppm) and As (near 13,000 ppm; 70 cm) occur rather in bottom horizons of soil profile. Noticeable positive correlations of LOI vs. Pb (r = 0.96), Cu (r = 0.90), Fe (r = 0.87), Ag (r = 0.94) together with SEA values from Utín soils indicate that studied elements have in fraction bound to organic matter and sulphides have a tendency to be bound rather to organic compounds. This is the main difference between the two localities because the studied elements in Dlouhá Ves soils have in the same fraction tendency to be bound just to sulphides. In addition to presupposed higher pedogenesis degree in distinctly older Utín soils, the difference between two soil profiles is acidobazic conditions in Dlouhá Ves soil profile, in which the pH/KCl is very low. Decomposition of organic matter is also slower in this environment. The lower degree of pedogenesis in Dlouhá Ves is also supported by in average lower values of frequency dependent magnetic susceptibility (χFD = 1–5 %).
STATISTICKÉ ZHODNOCENÍ SEISMICKÉ AKTIVITY ZÓNY MUR-MÜRZ-LEITHA
Authors: Růžička Vít 
Published: January 2016

Mur-Mürz-Leitha fault system represents the most important seismically active zone in the Eastern Alps. Its part of the geological units of the Eastern Alps. Pushing the influence of alpine units to the north during the Cretaceous there was a lateral extrusion, resulting in the formation of shear fractures (eg .: system MML). Based on data provided from the project ACORN, IPE and ZAMG. frequency-magnitude graph and temporal distribution chart since 1980 were compiled. Frequency-magnitude distribution show that borded of completeness of the data since 1980, have a value of magnitude 2 and higher. Therefore, the temporal distribution chart was created just since 1980, and magnitude of 2 and more. Above all the chart takes a set of occurrences of 2000, which number 37 events with a magnitude of 2 and 2 events with magnitude over 4. These occurrences come under the area 4. Then was made another temporal distribution chart since 1980, but this one is only for area 4. In area 4 Ebreichsdorf town is situated that is near the seismic swarm from the years of 2000 and 2013. The seismic swarm from 2013 is the similar like seismic swarm in 2000 just in a slightly smaller. These seismic occurrences of Ebreichsdorf are important, because they were macroseismic felt in the southern regions of the Czech Republic, including Brno.
MODELOVÁ CIRKULACE FLUID V EXPERIMENTÁLNÍ NÁDOBĚ MOCK-UP-CZ
Authors: Šrámek Martin , Kuchovský Tomáš 
Published: January 2016

Experiment simulating the storage of spent nuclear fuel in the canister filled by bentonite mixture took place in the Center of experimental Geotechnics (CEG) on the Faculty of Civil engineering of the Czech Technical University in Prague during the years 2002–2006. After the realisation of the experiment it was shown, that both non-homogeneous geochemical and temperature fields were established. The main aim of the work was focused on the evaluation of the fluid flow characteristics inside the container, especially on the direction and flow velocities influenced by the increased temperature. Numerical modelling using the SHEMAT computer code was used to simulate the fluid flow.Mathematical modelling confirmed the probable formation of the convection cells along the heater with variable velocities depending on the hydraulic and thermal properties of the bentonite mixture and on the physical properties of the saturating fuid. The generated flow field could be the driving force for the geochemical non-homogeneities.
Priming Dental Pulp Stem Cells With Fibroblast Growth Factor-2 Increases Angiogenesis of Implanted Tissue-Engineered Constructs Through Hepatocyte Growth Factor and Vascular Endothelial Growth Factor Secretion
Authors: Gorin Caroline , Rochefort Gael Y. , Bascetin Rumeyza , Ying Hanru , Lesieur Julie , Sadoine Jérémy , Beckouche Nathan , Berndt Sarah , Novais Anita , Lesage Matthieu , Hosten Benoit , Vercellino Laetitia , Merlet Pascal , Le-Denmat Dominique , Marchiol Carmen , Letourneur Didier , Nicoletti Antonino , Vital Sibylle Opsahl , Poliard Anne , Salmon Benjamin , Muller Laurent , Chaussain Catherine , Germain Stéphane 
Published: January 2016

Abstract

Tissue engineering strategies based on implanting cellularized biomaterials are promising therapeutic approaches for the reconstruction of large tissue defects. A major hurdle for the reliable establishment of such therapeutic approaches is the lack of rapid blood perfusion of the tissue construct to provide oxygen and nutrients. Numerous sources of mesenchymal stem cells (MSCs) displaying angiogenic potential have been characterized in the past years, including the adult dental pulp. Establishment of efficient strategies for improving angiogenesis in tissue constructs is nevertheless still an important challenge. Hypoxia was proposed as a priming treatment owing to its capacity to enhance the angiogenic potential of stem cells through vascular endothelial growth factor (VEGF) release. The present study aimed to characterize additional key factors regulating the angiogenic capacity of such MSCs, namely, dental pulp stem cells derived from deciduous teeth (SHED). We identified fibroblast growth factor-2 (FGF-2) as a potent inducer of the release of VEGF and hepatocyte growth factor (HGF) by SHED. We found that FGF-2 limited hypoxia-induced downregulation of HGF release. Using three-dimensional culture models of angiogenesis, we demonstrated that VEGF and HGF were both responsible for the high angiogenic potential of SHED through direct targeting of endothelial cells. In addition, FGF-2 treatment increased the fraction of Stro-1+/CD146+ progenitor cells. We then applied in vitro FGF-2 priming to SHED before encapsulation in hydrogels and in vivo subcutaneous implantation. Our results showed that FGF-2 priming is more efficient than hypoxia at increasing SHED-induced vascularization compared with nonprimed controls. Altogether, these data demonstrate that FGF-2 priming enhances the angiogenic potential of SHED through the secretion of both HGF and VEGF.

Significance
The results from the present study show that fibroblast growth factor-2 (FGF-2) priming is more efficient than hypoxia at increasing dental pulp stem cells derived from deciduous teeth (SHED)-induced vascularization compared with nonprimed controls. Together, these data demonstrate that FGF-2 priming enhances the angiogenic potential of SHED through the secretion of both hepatocyte growth factor and vascular endothelial growth factor.
Mesenchymal Stem Cells and Mononuclear Cells From Cord Blood: Cotransplantation Provides a Better Effect in Treating Myocardial Infarction
Authors: Chen Gecai , Yue Aihuan , Yu Hong , Ruan Zhongbao , Yin Yigang , Wang Ruzhu , Ren Yin , Zhu Li 
Published: January 2016

Abstract

The aim of this study was to evaluate the effect of cotransplanting mononuclear cells from cord blood (CB-MNCs) and mesenchymal stem cells (MSCs) as treatment for myocardial infarction (MI). Transplanting CD34+ cells or MSCs separately has been shown effective in treating MI, but the effect of cotransplanting CB-MNCs and MSCs is not clear. In this study, MSCs were separated by their adherence to the tissue culture. The morphology, immunophenotype, and multilineage potential of MSCs were analyzed. CB-MNCs were separated in lymphocyte separation medium 1.077. CD34+ cell count and viability were analyzed by flow cytometry. Infarcted male Sprague-Dawley rats in a specific-pathogen-free grade were divided into four treatment groups randomly: group I, saline; group II, CB-MNCs; group III, MSCs; and group IV, CB-MNCs plus MSCs. The saline, and CB-MNCs and/or MSCs were injected intramyocardially in infarcted rats. Their cardiac function was evaluated by echocardiography. The myocardial capillary density was analyzed by immunohistochemistry. Both cell types induced an improvement in the left ventricular cardiac function and increased tissue cell proliferation in myocardial tissue and neoangiogenesis. However, CB-MNCs plus MSCs were more effective in reducing the infarct size and preventing ventricular remodeling. Scar tissue was reduced significantly in the CB-MNCs plus MSCs group. MSCs facilitate engraftment of CD34+ cells and immunomodulation after allogeneic CD34+ cell transplantation. Cotransplanting MSCs and CB-MNCs might be more effective than transplanting MSCs or CB-MNCs separately for treating MI. This study contributes knowledge toward effective treatment strategies for MI.

Significance
This study assessed cotransplantation of hematopoietic stem cells (CD34+ cells) and mesenchymal stem cells (MSCs) for treatment of myocardial infarction (MI) in a rat model. The results demonstrate that MSCs and mononuclear cells from cord blood may have synergistic effects and cotransplantation might be more effective in the treatment of MI than transplanting MSCs and CD34+ cells separately. This study contributes knowledge toward a more effective treatment protocol for MI.
La sierra de Cartagena-La Unión (Murcia): un ejemplo de actividad turística a través del patrimonio minero
Authors: Morales Yago Francisco José 
Published: January 2016

El cese final en el año 1991 de la actividad minera en la Sierra de Cartagena-La Unión en la Región de Murcia supuso para esta comarca el inicio de un gran declive económico que no ha encontrado respuesta hasta tiempos recientes, en donde la iniciativa para la puesta en valor del importante legado minero-industrial está sirviendo de base en la creación de un proyecto turístico complementario al tradicional de sol y playa ubicado en La Manga del Mar Menor y demás espacios litorales. El análisis DAFO incluido como metodología principal de este trabajo permitirá a través de la participación de distintos colectivos conocer y analizar el presente así como la proyección de futuro de esta nueva actividad que potencialmente supondrá un importante cambio en la actividad socioeconómica de la comarca y por consiguiente de sus habitantes.
Oscillation up to 1.92 THz in resonant tunneling diode by reduced conduction loss
Authors: Maekawa Takeru , Kanaya Hidetoshi , Suzuki Safumi , Asada Masahiro 
Published: January 2016

Abstract
A large increase in oscillation frequency was achieved in resonant-tunneling-diode (RTD) terahertz oscillators by reducing the conduction loss. An n+-InGaAs layer under the air-bridge electrode connected to the RTD was observed to cause a large conduction loss for high-frequency current due to the skin effect. By introducing a new fabrication process removing the InGaAs layer, we obtained 1.92-THz oscillation, which extended the highest frequency of room-temperature electronic single oscillators. Theoretical calculations reasonably agreed with the experiment, and an oscillation above 2 THz is further expected with an improved structure of the slot antenna used as a resonator and radiator.
Operational stability in pentacene thin-film transistors with threshold voltages tuned by oxygen plasma treatment
Authors: Kimura Yoshinari , Kitamura Masatoshi , Kitani Asahi , Arakawa Yasuhiko 
Published: January 2016

Abstract
Pentacene-based organic thin-film transistors (TFTs) having a SiO2 gate dielectric treated with oxygen plasma have been investigated for control of the threshold voltage. The threshold voltage changed in the wide range from −15 to 80 V, depending on plasma treatment time, AC power for plasma generation, and gate dielectric thickness. The threshold voltage change was attributed to negative charges induced on and/or near the surface of the gate dielectric. The threshold voltage change on the order of 1 V was particularly proportional to plasma treatment time. The predictable change enables the control of threshold voltage in this range. In addition, the effect of gate bias stress on threshold voltage was examined. The results suggested that gate bias stress does not negate the threshold voltage change induced by plasma treatment.
Fabrication of highly (110)-oriented BaCeO3-based proton-conductive oxide thin films by RF magnetron sputtering method
Authors: Sato Tomoya , Inoue Takaaki , Ichinose Daichi , Funakubo Hiroshi , Uchiyama Kiyoshi 
Published: January 2016

Abstract
A proton-conductive BaCe0.9Y0.1O3−δ (BCYO) thin-film, one of the candidates for the electrolyte of intermediate-temperature solid oxide fuel cells (IT-SOFCs), was deposited on (111)Pt/TiO2/SiO2/(100)Si substrate by the RF magnetron sputtering method. The sputtering conditions, i.e., deposition temperature, pressure, and sputtering gases, were examined to improve the crystallinity of the films. The BCYO films deposited at more than 500 °C were well crystallized and showed only 110 diffraction. The addition of O2 into the sputtering gas causes adverse results of lower crystallinity and lower deposition rates. A wide-range XRD reciprocal space mapping also revealed that the (110)-oriented BCYO films can be obtained on (111)Pt/TiO2/SiO2/(100)Si substrates without the need to use any buffer layers. We consider that this BCYO film possibly shows high proton conductivity and may be a suitable material for the SOFC electrolyte because of its high crystallinity.