bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the application of the finite cell method to static analysis of trabecular bone tissue specimen using high‐resolution microCT data
Authors: Shahmohammadi Mohammad Amin , Fiedler Imke , vom Scheidt Annika , Busse Björn , Düster Alexander 
Published: October 2024

AbstractThis study aims to introduce a robust numerical approach to simulate complex small‐scale mediums such as trabecular bone tissue in form of a cylindrical specimen taken from human vertebra. Consideration of previous related studies indicates that there are several challenges in utilizing standard finite element (FE) techniques for the analysis of such biomechanical structures. This is mainly due to their time‐consuming procedure required for generating geometry conforming meshes. In this regard, the finite cell method (FCM) is an interesting alternative because it is based on the concept of the fictitious domain technique in which underlying meshes do not need to conform to the boundary of the domain. Since the considered trabecular bone tissue consists of a complex small‐scale internal morphology, generating a FE mesh is rather complicated. So, the application of the FCM can be justified by overcoming the mentioned shortcomings of FE methods for this problem. Using FCM, it is possible to simulate the mentioned trabecular cylinder from vertebral body using higher order cells of regular shapes where the geometry is taken care of through the numerical integration. The input for the present numerical tool corresponding to the complex internal morphology of the proposed tissue is given by a high‐resolution microCT scan. The outcome of the FCM will be compared to results obtained by mechanical testing of the specimen.
The temporal dynamics of perceived stress and depression in college students: An ecological momentary assessment
Authors: Feng Guo , Xu Xiaxia , Wu Jie , Lei Jiawei 
Published: October 2024

AbstractPrevious studies have implied that stress is a risk factor for depression, but relatively little is known about how healthy individuals' stress dynamically affects depression as a mood in daily life. Therefore, an ecological momentary assessment study was conducted among 141 college students to test the temporal dynamic effect of daily perceived stress on depression and the underlying mediating and moderating role of rumination. Perceived stress, state rumination, and depression were measured using self‐compiled questionnaire three times a day over 12 days. Trait rumination was measured with the Nolen‐Hoeksema Ruminative Response Scale. Hierarchical linear models with HLM 7.0 were adopted to examine the mediation and moderation effects. In the mediation model, the greater the daily perceived stress at time t, the higher the state rumination at time t + 1, and state rumination at t + 1 positively predicted college students' depression at t + 2. In the moderation model, trait rumination significantly facilitated perceived stress‐induced depression. These results verified that daily perceived stress could affect college students' depression directly or indirectly through the critical mediating mechanism of state rumination, and this effect would be exacerbated with a higher level of trait rumination.
High‐efficiency synthesis of the transparent cyclo‐olefin elastomers with high catalytic activity at high temperature in a gas‐liquid slug flow mini‐tubular reactor
Authors: Liu Xue , Li Hao , Jie Su‐yun , Wang Qi , Chen Zhong‐Ren , Cao Kun , Fan Zhi‐qiang 
Published: October 2024

AbstractA facile approach for synthesis of the ethylene‐norbornene copolymer (ENC) elastomers via creatively utilizing ethylene “rich” and “poor” regions within slug flow was developed by the copolymerization of ethylene (E) and norbornene (NB) in toluene solution under high temperature (90–150°C) and moderate pressure with ultra‐high catalytic activity of 2.7–11.3 × 109 gpolymer molZr−1 h−1 and efficiency of 10–17.5 kgpolymer gZr−1, respectively. For the ENC elastomers with random structure, a sharply decline of tensile strength (σ from 53.5 to 6.4 MPa), Young's modulus (E from 723.6 to 7.5 MPa) and toughness (UT from 60.3 to 12.0 MJ·m−3) were observed with the decrease of glass‐transition temperatures (Tg) of the copolymers, while the elongation at break showed the opposite trend. The ENC elastomers with multiblock structure enhanced stiffness and toughness balance with tensile strength (σ) of 13.6–41.2 MPa, Young's modulus (E) of 23.5–33.7 MPa, toughness (UT) of 31.9–47.3 MJ·m−3, and tunable elongation at break (ε = 325%–515%), which may be attribute to a certain number of controlled tiny PE crystallites acting as critical physical cross‐linking points. Moreover, all of the ENC elastomers exhibited excellent transparency (≥88%). This strategy is rather fascinating because of its simple procedure, the utilization of slug flow pattern to generate the cyclo‐olefin copolymers of diverse structures and properties, usage of only one common metallocene catalyst with two cocatalysts to achieve remarkable activity and efficiency under high temperature and the production of cyclo‐olefin elastomers with excellent performances. It is envisioned that this work would provide new perspective for the employment of flow patterns to make a difference in polymer synthesis.
Mentha aquatica (Water Mint) as a Source of Active Pharmaceutical and Cosmetic Ingredients: A Critical Review
Authors: Pires Patrícia C. , Motallebi Mahzad , Marques Mário Pedro , Correia Mafalda , Sharma Ankur , Damiri Fouad , Hameed Huma , Singh Sachin Kumar , Dua Kamal , Jha Niraj Kumar , Cabral Célia , Veiga Francisco , Paiva‐Santos Ana Cláudia 
Published: October 2024

ABSTRACT
Mentha aquatica L., or water mint, is an important member of the Mentha genus, and has long been used in traditional medicine, mainly to treat respiratory diseases such as the common cold. Nevertheless, although over the years many studies have shown that it's potential grows beyond this use, a review that highlights M. aquatica L.'s true potential is still lacking. Thus, the main purpose of the present article is to provide a thorough and multidisciplinary critical review of M. aquatica L., including its phytochemical characterization, main bioactivities, and current marketed cosmetic products. Many compounds have been identified as part of M. aquatica L. composition, such as terpenes, phenolic acids, phenols, and terpenoids, which have been linked to a vast therapeutic potential, namely anti‐inflammatory, antioxidant, antibacterial, antifungal, antiobesity, and hepatoprotection bioactivities, with additional anticancer potential for several types of tumors (breast, lung, and skin), and psycho and neuroactive potential in depression, or Alzheimer's or Parkinson's disease. Additionally, it has been proven to be suitable for cosmetic application since several cleansing, hydrating, protecting, and/or odor masking products containing it are already available, with the main functions attributed to M. aquatica including refreshing/cooling effects, calming/soothing/relaxing effects, and purifying effects, properties closely related to its anti‐inflammatory and antioxidant bioactivities. Hence, M. aquatica is an extremely versatile plant, with its extracts and essential oils having great therapeutic and cosmetic potential. With many marketed cosmetic products, future studies should focus on this plant's medicinal aspects, so that 1 day it can be part of therapeutic regimens.
Adaptive fixed‐time prescribed performance regulation for switched stochastic systems subject to time‐varying state constraints and input delay
Authors: Chen Xuemiao , Li Jing , Wu Jian , Yang Chenguang 
Published: October 2024

AbstractIn this article, the adaptive fixed‐time prescribed performance (FTPP) regulation is investigated for a class of time‐varying state constrained switched stochastic systems with input delay. The time‐varying barrier Lyapunov function and a compensation system are presented, respectively, to deal with the design problems caused by the existence of both time‐varying state constraints and input delay. Some radial basis function neural networks are used to approximate unknown functions, and the common Lyapunov function method is displayed to handle the switched signals. Besides, by designing a fixed‐time prescribed performance function, the desired adaptive neural controller is constructed. Compared with the existing works for state constrained control problem, the FTPP regulation control scheme is first proposed for time‐varying state constrained stochastic switched systems under input delay, and the adaptive dynamic surface control scheme with the nonlinear filter is designed to solve the problem of “explosion of complexity.” Based on the stochastic stability theory, the FTPP of system output is achieved, other system state variables are restricted in the predefined regions, and all signals of this closed‐loop system remain bounded in probability. Finally, the availability of the proposed control scheme is illustrated via two simulation examples.
Bipartite containment control of multi‐agent systems under DoS attacks: an event‐triggered scheme
Authors: Liu Zihan , Zhang Hao , Wang Zhuping 
Published: October 2024

AbstractThis paper investigates the problem of bipartite containment control for multi‐agent systems (MASs) under denial‐of‐service (DoS) attacks with event‐triggered scheme. The DoS attacks can cause disruptions to communication channels, suspending or crashing services. In order to minimize the impact of the attacks on the control process, this paper introduces a bipartite containment control protocol with a resilient event‐triggered scheme, which enables the MASs not only to resist DoS attacks but also to optimize the utilization of resources and accomplish the control target. After considering the previous, the paper suggests a new observer to estimate the state of agents in order to cope with the unmeasurable state of MASs. Moreover, Zeno behavior avoidance is rendered more effective by the introduction of a positive constant in the event‐triggered function. At last, simulation data and results are given, thus verifying the feasibility of solving the bipartite containment problem under DoS attacks.
Beyond borders: Assessing global sustainability through interconnected systems
Authors: Zhang Junze , Skene Keith R. , Wang Saige , Ji Qiulei , Zheng Heran , Zhou Chaowei , Tian Kailan , Pradhan Prajal , Meadows Michael E. , Fu Bojie 
Published: October 2024

AbstractThe many complex interconnections among countries driven by natural and socio‐economic processes have a crucial impact on regional and global sustainability, yet a robust and systematic way to quantify this impact is lacking. Here we introduce two complementary approaches to bridge this key methodological gap. The first entails constructing a new sustainability index capable of systematically considering pertinent indicators of interdependencies and spillovers between countries. To minimize ambiguities associated with the aggregated index, the second approach establishes a spatial analysis framework, one designed to explicitly incorporate dimensions of interdependence and spillovers, along with buffer and multiplier effects, enabling us to distinguish and gage the impact of spatial interconnections on regional and global sustainability. Overall, the two approaches applied in tandem reinforce the joint principles of ‘one Earth’ and ‘leaving no one behind’, and can help to clarify countries' responsibilities in respect of global sustainable development.
Synthesis and Anticancer Evaluation of Novel Coumarin Derivatives
Authors: Dam Thi Thanh Hai , Chan Doan Phuong Anh , Phan Minh Tan , To Thi Kim Linh , Vo Thanh , Phan Thai Son , Hoang Viet , Le Thi Thanh Huong , Vu Thien Y , Vo Duc Duy , Nguyen Phu Hung , Le Tin Thanh 
Published: October 2024

AbstractNine new coumarin derivatives of 2‐(7‐hydroxy‐2‐oxo‐2H‐chromen‐4‐yl)acetic acid 6a–i have been successfully synthesized through amide coupling with various substituted anilines and 2‐aminopyridines. The synthesized derivatives were screened for anticancer activity using MTT assay on MCF‐7 cell line. The results showed that compound 6b inhibited MCF‐7 cell growth in a dose‐dependent manner and reached 47% inhibition at 40 µM, being better than starting material 5 and references 3 and 5FU drug. Moreover, 6b inhibited significantly 3D tumorsphere formation. The para‐Br substitution of 6b seems to be important for activity. Docking study suggests estrogen receptor and/or 3a‐HSD type 3 protein could be the target(s) for anticancer activity of this class of compounds. Further optimization of compound 6b should lead to more potent compound.
N‐Iodosuccinimide in Oxidative Dimerization of Methyl Cinnamates
Authors: Galgano Pierantonio , Santarsiere Alessandro , Funicello Maria , Lupattelli Paolo , Ciriello Rosanna , Chiummiento Lucia 
Published: October 2024

AbstractHerein the reaction of methy cinnamates with N‐Iodosuccinimide (NIS) is reported and the possible formation of dihydrobenzofuryl dimeric derivatives (DHBF), known for their biological activities, is explored. Having an oxidizing capacity, we studied the behavior of NIS with methyl ferulate and under optimized reaction conditions we obtained its DHBF dimer in 35% yield. It is worth to note that we did not obtain the DHBF in his natural form, but rather as the demethylated compound, likely due to dismutation reactions activated by the presence of water in the solvent. Methyl caffeate reacted with NIS to furnish the DHBF dimer in 15% yield, while methyl coumarate and methyl isoferulate did not give any form of DHBF dimers, showing the importance of a hydroxyl group in para position on an activated system and an electron‐rich aromatic ring. An electrochemical investigation by cyclic voltammetry was carried out on the three cinnamates and confirmed the correlation between dimerization and oxidation potential: methyl ferulate and methyl caffeate dimerize, while methyl coumarate, due to its higher oxidizing potential, does not.
High‐Valence Mn MOF Inspired by Laccase Mediators Enables Versatile Nature‐Mimicking Catalysis
Authors: Xu Lili , Nan Jianli , Han Songxue , Yu Zhixuan , Wu Shuangli , Fang Youxing , Dong Shaojun 
Published: October 2024

AbstractIn nature, active Mn3+ –ligand complexes produced by laccase catalyzed oxidation can act as the low‐molecular mass, diffusible redox mediators to oxidize the phenolic substrates overcoming the limitations of natural enzymes. Learning from the metal–ligand coordination of natural functional units, high‐valence Mn metal–organic framework (Mn MOF) is constructed to simulate the catalysis in natural mediator system. Benefiting from the characteristics of nanoscale size, rich metal coordination unsaturated sites, and mixed valence state dominated by Mn(III), Nano Mn(III)‐TP exhibits superior laccase‐mimicking activity, whose Vmax (maximal reaction rate) is much higher than that of natural laccase. Referring to natural systems, relevant free radical experiments prove that the material induces the production of active oxygen species with the assistance of carboxylic acid, and active oxygen species further oxidize phenolic substrates. Based on its robust performances, the primary oxidative degradation of an emerging pollutant triclosan (TCS) is creatively applied, an important antiasthmatic medicine terbutaline sulfate (TBT) detection, and the synthesis of non‐toxic and black near‐natural dyes for dyeing. By simulating the essential mediators of natural enzymatic catalysis, an Mn MOF‐based material that demonstrates multiple novel applications is successfully developed, which introduces a new reliable strategy for achieving versatile nature‐mimicking catalysis.
Achieving Ultra‐Long Cycle Life of Zn Anode Using ZnSn(OH)6 Coating Layer via Desolvation Effect and Uniform Zn2+ Flux
Authors: Meng Yanhong , Bai Xinyu , Chen Hongming , Zhang Busheng , Liu Zijin , He Xinbo , Zhou Dan 
Published: October 2024

AbstractAqueous zinc‐ion batteries (AZIBs) are considered as a promising energy storage system because of good safety, low cost, abundant resources, and environmental friendliness. However, the bottlenecks including dendrite growth, hydrogen evolution, and corrosion seriously limit their practical application. Herein, a novel ZnSn(OH)6 coating layer with rich hydroxyl groups is employed to achieve highly stable Zn anode. The hydroxyl groups can feasibly interact with H2O molecules, contributing to the desolvation of hydrated Zn2+ and the inhibition of side reactions on Zn anode surface. Furthermore, according to the DFT calculation, the adsorption energy of Zn2+ among various sites on the surface of ZnSn(OH)6 coating layer is relatively large, which helps the uniform distribution of Zn2+ flux and the prevention of dendrite growth. Consequently, the ZnSn(OH)6@Zn anode delivers ultra‐long cycle life (6770 h), low polarization voltage (27 mV), and high Coulombic efficiency (99.2% over 800 cycles) at 1 mA cm−2, 1 mAh cm−2. Besides, the assembled NaV3O8·xH2O//ZnSn(OH)6@Zn full cell can operate stably for 1500 cycles at 2 A g−1 with a high specific capacity of 144.9 mAh g−1, demonstrating an excellent application potential. This simple and effective coating layer with high electrochemical performance provides an appealing strategy for the development of rechargeable AZIBs.
Tailored Permeation Through ≈1 nm Thick Carbon Nanomembranes by Subtle Changes in Their Molecular Design
Authors: Stroganov Vladislav , Nöthel Tabata , Hüger Daniel , Kruk Monika , Neumann Christof , Kozieł Krzysztof , Cyganik Piotr , Turchanin Andrey 
Published: October 2024

AbstractDue to their nanoscale thickness (≈1 nm) and exceptional selectivity for permeation of gases, nanomembranes made of 2D materials possess high potential for energy‐efficient nanofiltration applications. In this respect, organic carbon nanomembranes (CNMs), synthesized via electron irradiation‐induced crosslinking of aromatic self‐assembled monolayers (SAMs), are particularly attractive, as their structure can be flexibly tuned by choice of molecular precursors. However, tailored permeation of CNMs, defined by their molecular design, has not been yet demonstrated. In this work, it is shown that the permeation of helium (He), deuterium (D2) and heavy water (D2O) for CNMs synthesized from biphenyl‐based SAMs on silver (C6H5‐C6H4‐(CH2)n‐COO/Ag, n = 2–6) can be tuned by orders of magnitude by changing the structure of the molecular precursors by just a single methylene unit. The selectivity in permeation of D2O/D2 with an unprecedented value of 200 000 can be achieved in this way. The temperature‐dependent study reveals a clear correlation between the molecular design and the permeation mechanisms facilitating therewith tailored synthesis of molecular 2D materials for separation technologies.
3D Network of Liquid Metal‐Embedded Graphene via Surface Coating for Flexible Thermal Management
Authors: Luo Wenmei , Wei Baojie , Luo Tianlin , Li Baowen , Zhu Guimei 
Published: October 2024

AbstractThe rapid growth of flexible electronics has led to significant demand for relevant accessories, particularly highly efficient flexible heat dissipators. The fluidity of liquid metal (LM) makes it a candidate for realizing flexible thermal interface materials (TIMs). However, it is still challenging to combine LM with a conductive thermal network to achieve the synchronous improvement of thermal conductivity and flexibility. In this work, highly conductive flexible LM@GN/ANF films are made by coating LM nano‐droplets with graphene nanosheets (GN) via sonication, and then they are combined with aramid nanofibers (ANF). The LM@GN/ANF film is found to have a thermal conductivity of 5.67 W m−1 K−1 and a 24.5% reduction in Young's modulus, making it suitable for various flexible electronic applications such as wearable devices and biosensors.
Single‐Atom Catalysts with Isolated Cu1‐N4 Sites for Atopic Dermatitis Cascade Catalytic Therapy via Activating PPAR Signaling
Authors: Kuai Le , Huang Fang , Mao Lijie , Ru Yi , Jiang Jingsi , Song Jiankun , Chen Si , Li Ke , Li Yongyong , Dong Haiqing , Lu Xiangyu , Li Bin , Shi Jianlin 
Published: October 2024

AbstractAtopic dermatitis (AD) is one of the most common allergic skin disorders affecting over 230 million people worldwide, while safe and efficient therapeutic options for AD are currently rarely available. Reactive oxygen species (ROS) accumulation plays a key role in AD's disease progression. Therefore, a novel single‐atom catalyst is designed with isolated Cu1‐N4 sites anchored on carbon support (Cu1‐N4 ISAC), featuring triple antioxidant enzyme‐mimicking activities, for efficient AD cascade catalytic therapy (CCT). The excellent superoxide dismutase (SOD)‐, glutathione peroxidase (GPx)‐, and ascorbate peroxidase (APx)‐like activities of Cu1‐N4 ISACs enable the sequential conversion of O2•− to H2O2 and then to harmless H2O, thereby protecting keratinocytes from oxidative stress damage. Notably, two novel experimental methods are developed to directly prove the SOD‐GPx and SOD‐APx cascade catalytic activities for the first time. In vivo experiments show that Cu1‐N4 ISACs are more potent than a recommended typical medicine (halcinonide solution). Additionally, RNA sequencing and bioinformatic analysis reveal that Cu1‐N4 ISACs reduce inflammation and inhibit ROS production by activating PPAR signaling, which is aberrantly reduced in AD. Therefore, the synthesized catalytic medicine offers an alternative to alleviate AD and has the potential to serve as PPAR agonists for treating similar diseases.
Lower–Middle Ordovician brachiopods from the Eastern Cordillera of Peru: evidence of active faunal dispersal across Rheic and Iapetus oceans
Authors: Colmenar Jorge , Chacaltana César Augusto , Gutiérrez‐Marco Juan Carlos 
Published: October 2024

AbstractNew Floian and early middle Darriwilian brachiopod assemblages of the San José Formation of the Eastern Cordillera of Peru are presented. A new genus and species, Apurimella santiagoi, and two new species, Phragmorthis henrylunae and Nocturnellia ashaninka, are described. The assemblages also contain additional characteristic taxa demonstrating links with other proto‐Andean localities (Peruvian Altiplano, Argentinian Eastern Cordillera, Famatina) as well as with some localities of Baltica (Estonia, Ingria, Norway), Ganderia (Anglesey, Tramore, Indian Bay, Summerford, Miramichi), peri‐Laurentia (Mayo, Svalbard) and Laurentia (Klamath Mountains). Those shared genera indicate dynamic faunal exchanges between the Peruvian Eastern Cordillera and these terranes during the Early–Middle Ordovician transition, suggesting active brachiopod dispersal mechanisms across the Rheic and Iapetus oceans. These connections seem to have still been active by the middle Darriwilian, as suggested by the presence of Phragmorthis in the Darriwilian assemblages of Cuyania and Laurentia. Similarly, the new Peruvian Nocturnellia species is of particular interest, given that this genus is likely to have originated in South China during the Floian, but extended its distribution to Avalonia and to high‐latitude peri‐Gondwana by the Dapingian. It thrived there until the middle Darriwilian, but by that time had also reached the proto‐Andean margin either via Avalonia across the Rheic Ocean or along the Gondwanan coast from high‐latitude settings. All of these occurrences improve our knowledge of Early–Middle Ordovician brachiopod faunas of the northern Central Andean Basin and their relationships with contemporaneous faunas worldwide.