bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of extracorporeal cardiopulmonary resuscitation on neurological and cardiac outcome after ischaemic refractory cardiac arrest
Authors: Cesana Francesca , Avalli Leonello , Garatti Laura , Coppo Anna , Righetti Stefano , Calchera Ivan , Scanziani Elisabetta , Cozzolino Paolo , Malafronte Cristina , Mauro Andrea , Soffici Federica , Sulmina Endrit , Bozzon Veronica , Maggioni Elena , Foti Giuseppe , Achilli Felice 
Published: October 2017

Background: Extracorporeal cardiopulmonary resuscitation is increasingly recognised as a rescue therapy for refractory cardiac arrest, nevertheless data are scanty about its effects on neurologic and cardiac outcome. The aim of this study is to compare clinical outcome in patients with cardiac arrest of ischaemic origin (i.e. critical coronary plaque during angiography) and return of spontaneous circulation during conventional cardiopulmonary resuscitation vs refractory cardiac arrest patients needing extracorporeal cardiopulmonary resuscitation. Moreover, we tried to identify predictors of survival after successful cardiopulmonary resuscitation. Methods: We enrolled 148 patients with ischaemic cardiac arrest admitted to our hospital from 2011–2015. We compared clinical characteristics, cardiac arrest features, neurological and echocardiographic data obtained after return of spontaneous circulation (within 24 h, 15 days and six months). Results: Patients in the extracorporeal cardiopulmonary resuscitation group ( n=63, 43%) were younger (59±9 vs 63±8 year-old, p=0.02) with lower incidence of atherosclerosis risk factors than those with conventional cardiopulmonary resuscitation. In the extracorporeal cardiopulmonary resuscitation group, left ventricular ejection fraction was lower than conventional cardiopulmonary resuscitation at early echocardiography (19±16% vs 37±11 p<0.01). Survivors in both groups showed similar left ventricular ejection fraction 15 days and 4–6 months after cardiac arrest (46±8% vs 49±10, 47±11% vs 45±13%, p not significant for both), despite a major extent and duration of cardiac ischaemia in extracorporeal cardiopulmonary resuscitation patients. At multivariate analysis, the total cardiac arrest time was the only independent predictor of survival. Conclusions: Extracorporeal cardiopulmonary resuscitation patients are younger and have less comorbidities than conventional cardiopulmonary resuscitation, but they have worse survival and lower early left ventricular ejection fraction. Survivors after extracorporeal cardiopulmonary resuscitation have a neurological outcome and recovery of heart function comparable to subjects with return of spontaneous circulation. Total cardiac arrest time is the only predictor of survival after cardiopulmonary resuscitation in both groups.
Development of a network game for coordination of service delivery to people with a chronic illness
Authors: van den Oord Steven , Bertels Floris , Geurts Jac , Lenstra Remco , Kenis Patrick , Cambré Bart 
Published: October 2017

Introduction In this article, network governance is examined by using a network game that enables participants to interact and communicate about the coordination of service delivery by playing a role in a simulated organizational network. Methods The research design can be described as a data-driven inductive approach in which data were collected during two stages based on a participatory model building approach as a form of action science. The data analysis was a reflexive and iterative process of going back and forth to the thematic analysis of the audiovisual recordings and the content analysis of the surveys. We report the interim findings as well as evaluate the network game based on two game sessions each with 18 participants held in 2017. Results The interim findings of the two game sessions provide various instances in which participants acknowledged the validity of day-to-day practices of network governance. The findings suggest that appointing a network governance form is necessary to coordinate and integrate interactions among and between networks. Conclusion This study presents how a gaming and simulation approach to scholars, public leaders and managers replicates the functioning of organizational networks. Moreover, the approach was experienced as being supportive for informing its participants on how organizational networks are effectively structured, governed and managed in the context of coordinated service delivery for people with a chronic illness in Flanders (Belgium). It is recommended for future research to apply a quasi-experimental research design in which dimensions of network governance are manipulated to examine the behavioral underpinnings of goal-directed networks.
The role of workplace accommodations in the employment of people with disabilities
Authors: Anand Priyanka , Sevak Purvi 
Published: October 2017

AbstractWe explore the role of workplace accommodations in reducing employment barriers and improving the employment of people with disabilities. We do so using data from the 2015 Survey of Disability and Employment on people with disabilities who applied for vocational rehabilitation services in three states. The results show that at least one third of nonworking people with disabilities reported employment barriers that could be addressed by workplace accommodations, such as lack of transportation and an inaccessible workplace. We also find that receiving certain types of workplace accommodations, such as help with transportation, flexible work schedules, or a personal care attendant, is positively correlated with being employed at the time of the survey. Finally, people who are in poor health or have physical disabilities were more likely to perceive workplace inaccessibility as a barrier but less likely to have received accommodations in their current or most recent job. This suggests that people with these characteristics may be good candidates to target for greater access to workplace accommodations.
Glucagon-like peptide receptor agonists attenuate advanced glycation end products-induced inflammation in rat mesangial cells
Authors: Chang Jui-Ting , Liang Yao-Jen , Hsu Chia-Yu , Chen Chao-Yi , Chen Po-Jung , Yang Yi-Feng , Chen Yen-Lin , Pei Dee , Chang Jin-Biou , Leu Jyh-Gang 
Published: October 2017

Abstract
Background
Hyperglycemia-induced advanced glycation end products (AGEs) and receptor for AGEs (RAGE) production play major roles in progression of diabetic nephropathy. Anti-RAGE effect of peroxisome proliferator-activated receptor-delta (PPARδ) agonists was shown in previous studies. PPARδ agonists also stimulate glucagon-like peptide-1 (GLP-1) secretion from human intestinal cells.

Methods
In this study, the individual and synergic anti-inflammatory effects of GLP-1 receptor (exendin-4) and PPARδ (L-165,041) agonists in AGE-treated rat mesangial cells (RMC) were investigated.

Results
The results showed both exendin-4 and L-165,041 significantly attenuated AGE-induced IL-6 and TNF-α production, RAGE expression, and cell death in RMC. Similar anti-inflammatory potency was seen between 0.3 nM exendin-4 and 1 μM L-165,041. Synergic effect of exendin-4 and L-165,041 was shown in inhibiting cytokines production, but not in inhibiting RAGE expression or cell death.

Conclusions
These results suggest that both GLP-1 receptor and PPARδ agonists have anti-inflammatory effect on AGE-treated rat mesangial cells.
Evidence Basis for Regional Anesthesia in Ambulatory Arthroscopic Knee Surgery and Anterior Cruciate Ligament Reconstruction: Part II: Adductor Canal Nerve Block—A Systematic Review and Meta-analysis
Authors: Sehmbi Herman , Brull Richard , Shah Ushma Jitendra , El-Boghdadly Kariem , Nguyen David , Joshi Girish P. , Abdallah Faraj W. 
Published: October 2017

BACKGROUND:
Adductor canal block (ACB) has emerged as an effective analgesic regional technique for major knee surgeries in the last decade. Its motor-sparing properties make it particularly attractive for ambulatory knee surgery, but evidence supporting its use in ambulatory arthroscopic knee surgery is conflicting. This systematic review and meta-analysis evaluates the analgesic effects of ACB for ambulatory arthroscopic knee surgeries.

METHODS:
We conducted a comprehensive search of electronic databases for randomized controlled trials examining the analgesic effects of ACB compared to control or any other analgesic modality. Both minor arthroscopic and anterior cruciate ligament reconstruction (ACLR) surgeries were considered. Rest and dynamic pain scores, opioid consumption, opioid-related adverse effects, time to first analgesic request, patient satisfaction, quadriceps strength, and block-related complications were evaluated. Data were pooled using random-effects modeling.

RESULTS:
Our search yielded 10 randomized controlled trials comparing ACB with placebo or femoral nerve block (FNB); these were subgrouped according to the type of knee surgery. For minor knee arthroscopic surgery, ACB provided reduced postoperative resting pain scores by a mean difference (95% confidence interval) of −1.46 cm (−2.03 to −0.90) (P < .00001), −0.51 cm (−0.92 to −0.10) (P = .02), and −0.48 cm (−0.93 to −0.04) (P = .03) at 0, 6, and 8 hours, respectively, compared to control. Dynamic pain scores were reduced by a mean difference (95% confidence interval) of −1.50 cm (−2.10 to −0.90) (P < .00001), −0.50 cm (−0.95 to −0.04) (P = .03), and −0.59 cm (−1.12 to −0.05) (P = .03) at 0, 6, and 8 hours, respectively, compared to control. ACB also reduced the cumulative 24-hour oral morphine equivalent consumption by −7.41 mg (−14.75 to −0.08) (P = .05) compared to control. For ACLR surgery, ACB did not provide any analgesic benefits and did not improve any of the examined outcomes, compared to control. ACB was also not different from FNB for these outcomes.

CONCLUSIONS:
After minor ambulatory arthroscopic knee surgery, ACB provides modest analgesic benefits, including improved relief for rest pain, and reduced opioid consumption for up to 8 and 24 hours, respectively. The analgesic benefits of ACB are not different from placebo or FNB after ambulatory ACLR, suggesting a limited role of both blocks in this procedure. Paucity of trials dictates cautious interpretation of these findings. Future studies are needed to determine the role of ACB in the setting of local anesthetic instillation and/or graft donor-site analgesia.
No Significant Association Between the Transfusion of Small Volumes of Leukocyte-Depleted Red Blood Cells and Mortality Over 7 Years of Follow-up in Patients Undergoing Cardiac Surgery: A Propensity Score Matched Analysis
Authors: Koster Andreas , Zittermann Armin , Börgermann Jochen , Gummert Jan F. 
Published: October 2017

BACKGROUND:
The impact of red blood cell (RBC) transfusion on long-term clinical outcome is controversial.

METHODS:
We prospectively recorded follow-up data of 6124 cardiac surgical patients who received no transfusion (RBC− group) or 1–2 units of leukocyte-depleted RBC (RBC+ group) at our institution. The primary end point was overall mortality up to 7 years after cardiac surgery; secondary end point was coronary artery revascularization during follow-up. To correct for nonrandomized group assignment, propensity score (PS) matching was performed. A subgroup analysis was also performed in patients with preoperative anemia.

RESULTS:
PS matching was possible in 4118 patients. During a mean follow-up of 4.05 years (range, 0.0–7.3 years), 140 patients (14.6%) died in the RBC− group and 173 (17.2%) died in the RBC+ group. The hazard ratio for the RBC+ group versus the RBC− group was 1.00 (95% confidence interval, 0.79–1.25; P = .969). The number of revascularizations was 96 (9.9%) and 125 (10.6%), respectively, with a hazard ratio of 1.21 (95% confidence interval, 0.92–1.58; P = .166) for the RBC+ group. Preoperative anemia was not a risk factor for postoperative mortality, even when patients were transfused.

CONCLUSIONS:
This PS-matched analysis does not provide evidence for an association of the transfusion of small volumes of leukocyte-depleted RBCs with an increased postoperative mortality in cardiac surgical patients. Moreover, preoperative anemia could not be identified as a risk factor for increased postoperative mortality.
Variations in household microclimate affect outdoor-biting behaviour of malaria vectors
Authors: Ngowo Halfan S. , Kaindoa Emmanuel Wilson , Matthiopoulos Jason , Ferguson Heather M. , Okumu Fredros O. 
Published: October 2017

Background: Mosquito behaviours including the degree to which they bite inside houses or outside is a crucial determinant of human exposure to malaria. Whilst seasonality in mosquito vector abundance is well documented, much less is known about the impact of climate on mosquito behaviour. We investigated how variations in household microclimate affect outdoor-biting by malaria vectors, Anopheles arabiensis and Anopheles funestus. Methods: Mosquitoes were sampled indoors and outdoors weekly using human landing catches at eight households in four villages in south-eastern Tanzania, resulting in 616 trap-nights over 12 months. Daily temperature, relative humidity and rainfall were recorded. Generalized additive mixed models (GAMMs) were used to test associations between mosquito abundance and the microclimatic conditions. Generalized linear mixed models (GLMMs) were used to investigate the influence of microclimatic conditions on the tendency of vectors to bite outdoors (proportion of outdoor biting). Results: An. arabiensis abundance peaked during high rainfall months (February-May), whilst An. funestus density remained stable into the dry season (May-August). Across the range of observed household temperatures, a rise of 1ºC marginally increased nightly An. arabiensis abundance (~11%), but more prominently increased An. funestus abundance (~66%). The abundance of An. arabiensis and An. funestus showed strong positive associations with time-lagged rainfall (2-3 and 3-4 weeks before sampling). The degree of outdoor biting in An. arabiensis was significantly associated with the relative temperature difference between indoor and outdoor environments, with exophily increasing as temperature inside houses became relatively warmer. The exophily of An. funestus did not vary with temperature differences. Conclusions: This study demonstrates that malaria vector An. arabiensis shifts the location of its biting from indoors to outdoors in association with relative differences in microclimatic conditions. These environmental impacts could give rise to seasonal variation in mosquito biting behaviour and degree of protection provided by indoor-based vector control strategies.
Species delimitation in the Caribbean Gesneria viridiflora complex (Gesneriaceae) reveals unsuspected endemism
Authors: Lambert François , Clark John L. , Joly Simon 
Published: October 2017

AbstractAccurate taxonomy and species boundaries are of great importance in biodiversity hotspots with high species endemicity like the Caribbean. Indeed, inaccurate species delimitations can affect biodiversity estimates and influence the decisions taken on conservation issues. The genera Gesneria and Rhytidophyllum constitute the main representatives of the Caribbean Gesneriaceae and contain a few complexes with unclear taxonomic boundaries that are characterized by a confusing history of taxonomic changes and by the presence of several recognized varieties and subspecies. Gesneria viridiflora is a good example of such a complex. Four geographically isolated subspecies are recognized that have similar but variable vegetative and reproductive characters, and numerous taxonomic changes have been suggested in this group over the years. In this study, we used multivariate approaches to delimit distinct clusters of individuals using morphological (qualitative and quantitative characters) and molecular data from four nuclear markers. These groups are then tested using a Bayesian coalescent species delimitation approach and compared using multivariate analyses of bioclimatic variables obtained from occurrence data. The results suggest the presence of four distinct species in this complex according to the unified species concept: G. quisqueyana, G.sintenisii ,G . sylvicola andG .viridiflora . We also maintain G. viridiflora subsp. acrochordonanthe that does not fulfill our criteria for a species but that shows morphological variation associated to a specific geographical area. A distribution map, an identification key to the species, and a taxonomic treatment are provided. The new taxonomy proposed in this study shows an unsuspected species endemism in some regions of the Caribbean and underlines the importance of investigating species delimitation in diversified groups containing taxonomically complex taxa with poorly defined boundaries.
Mind the Teachers! The Impact of Mindfulness Training on Self-Regulation and Classroom Performance in a Sample of German School Teachers
Authors: Rupprecht Silke , Paulus Peter , Walach Harald 
Published: October 2017

<p style="text-align:justify">Teacher wellbeing and performance is affected by their ability to cope with the demands of the profession. This pilot non-randomized, waitlist-controlled study investigated the impact of a mindfulness intervention (Mindfulness-Based Stress Reduction) on teachers' wellbeing, self-regulation ability and classroom performance applying a mixed-method design. The sample was comprised of 32 German school teachers (93% female) which were distributed to a control and intervention group. Compared to the control condition, the intervention showed medium to high effect sizes on most outcome variables at post-test and results were sustained at follow-up. Mediation analyses showed that changes in mindfulness at post-test mediated changes in outcome variables at follow-up. Unexpectedly, the intervention seemed to negatively affect teacher engagement. Qualitative interviews highlighted the way mindfulness may influence teacher engagement and improve performance. Limitations of this study and future directions of research are discussed. </p>
Horrible histories? Vampire television, period drama and spectacle
Authors: Jowett Lorna 
Published: October 2017

Abstract
Vampires are essentially immortal and thus, while contemporary vampire television series are generally set in the present, the epic scale of a vampire’s existence affords vast potential for period drama via flashback. This article examines the different ways vampire TV has accessed the spectacle of period drama, presenting an alternative version of its usual televisual self, and playing with a different set of genre conventions. Period flashbacks are designed to provide novelty and spectacle, and also afford the pleasure of seeing a different version of a well-known character appearing in a new context. Yet, this article argues that contemporary vampire television series, exemplified by Angel (1998–2004), The Vampire Diaries (2009–17), True Blood (2008–14) and Being Human (2008–13), tie this new perspective to recurring characters and ongoing thematic preoccupations, balancing novelty and the epic sweep of historical period with the familiarity and repetition characteristic of serial drama on television. Thus, vampire TV shows integrate elements and conventions of period drama but use them, sometimes subverting and disrupting them, to feed ongoing development of narrative, characters, themes and aesthetics common to many vampire representations. This article identifies and examines similarities between vampire television and period drama, and the ways in which the combination of two sets of televisual conventions both mesh harmoniously and produce interesting tensions in the former.
Cardiovascular Risk Factors in White Collar Workers Under Shift Work
Authors: Vangelova K. 
Published: October 2017

Abstract
Shift work is associated with circadian disruption, disturbs sleep and social life, and modifies disease risk factors, and thus can potentially contribute to various chronic diseases including cardiovascular diseases. The aim of the study was to follow cardiovascular risk in white collar workers under shift work. Cardiovascular risk was studied in sound-engineering staff in sound-recording production. The study encompassed 168 employees (46% males and 54% females) working under shift work of age 48.04 ± 8.8 years and length of service 21.6 ± 4.6 years. Our data show that 31.1% of the investigated employees were hypertensive, of which 22.6% had preliminary physician’s diagnosis of arterial hypertension, showing comparatively high rates of undiagnosed hypertension, higher in males in comparison to females. The TC and HDL-C were slightly higher with the females, while the triglycerides and TC/HDL-C ratio with the males. High rates of smoking, physical inactivity, overweight and obesity were found with both genders, slightly higher with the females. The preventive approach incorporating regular medical surveillance of shift workers and health promotion covering both life style factors and shift work organization is needed for tackling CVD in shift workers for better cardiovascular health.
Determination of Maximum Horizontal Distance (XMHD) Travelled by Landfill Leachate from Lapite Dumpsite in Ibadan, Southwestern Nigeria
Authors: Popoola Olatunde I. , Fakunle Mutiu A. 
Published: October 2017

Abstract
This study was designed to determine Maximum Horizontal Distance (XMHD) travelled by landfill leachate. Twenty - nine Schlumberger Vertical Electrical Soundings (VES) were conducted at 10.0m intervals away from four sides A, B, C and D of Lapite dumpsite. One VES point conducted outside the vicinity of the dumpsite served as a control. VES data were processed. Lowest resistivity values (Y) of VES points and the control point (Yc) were extracted. Curves of Y against X fitted best to yield an equation. XMHD was determined from the generated equation when Y = Yc. The determined (XMHD) on the four sides ranged from78.95m to 179.86m.
A Note On Chess In 19th Century Turkestan
Authors: Markov Georgi 
Published: October 2017

Abstract
A note by A. Chernevski in the 1877 Shakhmatny Listok described two chess variants played in Samarkand, present-day Uzbekistan. One, the “Bukharan game”, is a slightly modified version of shatranj, similar to Rumi chess as described in Murray’s History of Chess. The other, the “Persian game with a queen” resembles to some extent the Persian chess described in 1846 in the Chess Player’s Chronicle but differs from it in several important aspects. Chernevski’s information, which includes recorded games by native players, is absent from later sources on chess history. A summary of Chernevski’s report is provided, with a discussion of several other historical chess variants, and various errors that have crept into their description in the literature.