bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case study of records management practices in historic motor sport
Authors: Joseph Pauline 
Published: November 2016

Purpose
This paper aims to report on empirical research that investigated the records management practices of two motor sport community-based organisations in Australia.

Design/methodology/approach
This multi-method case study was conducted on the regulator of motor sport, the Confederation of Australian Motor Sport Ltd (CAMS) and one affiliated historic car club, the Vintage Sports Car Club (VSCC), in Western Australia. Data were gathered using an online audit tool and by interviewing selected stakeholders in these organisations about their organisation’s records management practices.

Findings
The findings confirm that these organisations experience significant information management challenges, including difficulty in capturing, organising, managing, searching, accessing and preserving their records and archives. Hence, highlighting their inability to manage records advocated in the best practice Standard ISO 15489. It reveals the assumption of records management roles by unskilled members of the group. It emphasises that community-based organisations require assistance in managing their information management assets.

Research limitations/implications
This research focused on the historic car clubs; hence, it did not include other Australian car clubs in motor sport. Although four historical car clubs, one in each Australian state, were invited to participate, only the VSCC participated. This reduced the sample size to only one CAMS-affiliated historical car club in the study. Hence, further research is required to investigate the records management practices of other CAMS affiliated car clubs in all race disciplines and to confirm whether they experienced similar information management challenges. Comments from key informants in this project indicated that this is likely the case.

Practical implications
The research highlights risks to the motor sport community’s records and archives. It signals that without leadership by the sport’s governing body, current records and community archives of CAMS and its affiliated car clubs are in danger of being inaccessible, hence lost.

Social implications
The research highlights the risks in preserving the continuing memory of records and archives in leisure-based community organisations and showcases the threats in preserving its cultural identity and history.

Originality/value
It is the first study examining records management practices in the serious leisure sector using the motor sport community.
Development and feasibility of the misuse, abuse, and diversion drug event reporting system (MADDERS®)
Authors: Treister Roi , Trudeau Jeremiah J. , Van Inwegen Richard , Jones Judith K. , Katz Nathaniel P. 
Published: November 2016

Background and ObjectivesInappropriate use of analgesic drugs has become increasingly pervasive over the past decade. Currently, drug abuse potential is primarily assessed post‐marketing; no validated tools are available to assess this potential in phase II and III clinical trials. This paper describes the development and feasibility testing of a Misuse, Abuse, and Diversion Drug Event Reporting System (MADDERS), which aims to identify potentially abuse‐related events and classify them according to a recently developed classification scheme, allowing the quantification of these events in clinical trials.MethodsThe system was initially conceived and designed with input from experts and patients, followed by field‐testing to assess its feasibility and content validity in both completed and ongoing clinical trials.ResultsThe results suggest that MADDERS is a feasible system with initial validity. It showed higher rates of the triggering events in subjects taking medications with known abuse potential than in patients taking medications without abuse potential. Additionally, experts agreed on the classification of most abuse‐related events in MADDERS.Discussion and ConclusionsMADDERS is a new systematic approach to collect information on potentially abuse‐related events in clinical trials and classify them. The system has demonstrated feasibility for implementation. Additional research is ongoing to further evaluate its validity.Scientific SignificanceCurrently, there are no validated tools to assess drug abuse potential during clinical trials. Because of its ease of implementation, its systematic approach, and its preliminary validation results, MADDERS could provide such a tool for clinical trials. (Am J Addict 2016;25:641–651)
Do directly acting antiviral agents for HCV increase the risk of hepatic decompensation and decline in renal function? Results from ERCHIVES
Authors: Butt A. A. , Ren Y. , Marks K. , Shaikh O. S. , Sherman K. E. ,   For the ERCHIVES study
Published: November 2016

SummaryBackgroundDirectly acting antiviral agents (DAA) have been associated with hepatic decompensation, especially in patients with pre‐treatment cirrhosis, but this risk is not well defined.AimTo determine the incidence of hepatic decompensation, liver transplantation, death and worsening renal function in patients treated with a Paritaprevir/ritonavir, Ombitasvir, Dasabuvir (PrOD), sofosbuvir/simeprevir or sofosbuvir/ledipasvir regimen.MethodsWe followed ERCHIVES participants treated with the above regimens for up to 12 weeks post‐treatment. We excluded those with HIV, HBsAg+ and pre‐existing diagnosis of hepatic decompensation and hepatocellular carcinoma.ResultsOf 3728 persons on PrOD, 1578 on sofosbuvir/simeprevir and 10 440 on sofosbuvir/ledipasvir, incidence rates (95% CI) of hepatic decompensation/1000 patient‐years were 10.6 (5.89–17.36) for the PrOD, 32.4 (20.74–48.16) for the sofosbuvir/simeprevir and 13.0 (9.74–17.10) for the sofosbuvir/ledipasvir. Among those with baseline cirrhosis, these rates were 36.9 (19.1–64.5), 61.8 (38.2–94.5) and 41.1 (29.9–55.2) respectively, while among those without cirrhosis at baseline, these rates were 2.7 (0.6–8.0), 7.5 (1.5–21.8) and 2.7 (1.2–5.4). Advanced fibrosis was associated with increased risk of hepatic decompensation in all groups [HR (95% CI) per 0.5 unit increase in FIB‐4 score: PrOD 1.11 (1.07–1.16); sofosbuvir/simeprevir 1.03 (1.01–1.05); sofosbuvir/ledipasvir 1.02 (1.01–1.03)]. There were no deaths. Proportion of persons with eGFR decrease >30 ml/min/1.73 m2 was higher among the PrOD group, but presence of cirrhosis did not appear to affect this.ConclusionsThe incidence of hepatic decompensation in persons treated with PrOD, up to 12 weeks after completion of treatment, was comparable to those treated with sofosbuvir/ledipasvir regimen, and was lower than among those treated with a sofosbuvir/simeprevir regimen. Such risk was predominantly observed in those with pre‐treatment cirrhosis.
An interactive training programme to treat body image disturbance
Authors: Gledhill Lucinda J. , Cornelissen Katri K. , Cornelissen Piers L. , Penton‐Voak Ian S. , Munafò Marcus R. , Tovée Martin J. 
Published: November 2016

ObjectivesAnorexia nervosa (AN) is a life‐threatening mental health condition. A core feature is a disturbance of body image, such that sufferers see themselves as fatter than they actually are.DesignWe tested the effectiveness of a novel training programme to recalibrate our participants’ perception of body size.MethodsIn a novel adaptation of a cognitive bias training programme, participants judged the body size of a series of female bodies and were given feedback to improve their accuracy over four daily training sessions. In Study 1, we recruited young women with high concerns about their body size for a randomized controlled study. In Study 2, we then applied the training programme to a case series of women with atypical AN.ResultsIn Study 1, the training programme significantly improved the body size judgements of women with high body concerns compared to controls. We also found evidence of improved body image and reduced eating concerns in this group. In Study 2, the programme again recalibrated the body size judgements of women with atypical AN. We also saw evidence of a clinically meaningful reduction in their body size and eating‐disordered concerns.ConclusionsThis training has the potential to be a valuable treatment used together with more traditional talking therapies.
Statement of contribution

What is already known on this subject?

A core feature of anorexia nervosa (AN) is an overestimation of body size; sufferers believe themselves to be larger than they are in reality. This study shows that an individual's perceptual boundary between what they classify as a fat versus a thin body is not immutable; it can be changed through a cognitive bias training programme.

What does this study add?

This means that body size overestimation may now be treatable.

Critically, as well as improving the accuracy of body size judgements, we also found a clinically significant improvement in participants’ eating‐disordered concerns.

This demonstrates that a targeted behavioural training regime can change body perception, and the central role that body overestimation has in eating‐disordered beliefs.
What affects perceptions of neighbourhood change?
Authors: Gosse Meghan , Ramos Howard , Radice Martha , Grant Jill L. , Pritchard Paul 
Published: November 2016

Key Messages

Residents of Halifax do not perceive economic or social and cultural changes in their neighbourhoods; however, they do perceive those to the built environment.
When residents of Halifax perceive changes in their neighbourhoods, they tend to be positive about them.
Tabular and regression analysis show that sense of belonging increases positive perceptions of neighbourhood change and older age decreases positive views of change.
Inferior vena cava collapsibility index, renal dysfunction, and adverse outcomes in patients with broad spectrum cardiovascular disease
Authors: Kim Yong‐Hyun , Kim Sunwon , Kim Jin‐Seok , Lim Sang‐Yup , Shim Wan‐Joo , Ahn Jeong‐Cheon , Song Woo‐Hyuk 
Published: November 2016

AimsThe clinical implication of the inferior vena cava collapsibility index (IVCCI) has not been well evaluated in patients with various cardiovascular diseases.Method and resultsThe relationships between clinical characteristics and echocardiographic indicators of the systemic intravascular volume status [IVCCI; the ratio of the early transmitral and early myocardial diastolic velocities (E/Em)] were evaluated at baseline, and the clinical status during follow‐up was compared across the IVCCI levels. Among 1166 patients (mean age=63.8±13.4 years), 934, 171, and 61 had high (≥50%), intermediate (25%–50%), and low (<25%) IVCCIs, respectively. Age‐, sex‐, and body mass index‐adjusted serum creatinine (sCr) levels were highest in patients with low IVCCI (P=.002) and E/Em >15 (P<.001). During follow‐up (1108±463 days), 67 patients died, and 38 of these deaths were cardiovascular related. Age, body mass index, heart failure (HF), sCr levels, and a low IVCCI (vs high IVCCI: hazard ratio [HR]=3.193, 95% confidence interval [CI]=1.297–7.857, P=.012) were associated with all‐cause mortality in multivariable analysis. HF, diuretic use, and a low IVCCI (vs high IVCCI: HR=4.428, 95% CI=1.406–13.104, P=.007) were significantly associated with cardiovascular mortality.ConclusionA low IVCCI was significantly associated with reduced renal function and was an independent risk factor for adverse outcomes, regardless of underlying cardiovascular disease and renal function.
Castration alters the number and structure of dendritic spines in the male posterodorsal medial amygdala
Authors: Zancan Mariana , Dall'Oglio Aline , Quagliotto Edson , Rasia‐Filho Alberto A. 
Published: November 2016

AbstractThe posterodorsal medial amygdala (MePD) is responsive to androgens and participates in the integration of olfactory/vomeronasal stimuli for the display of sexual behavior in rats. Adult gonadectomy (GDX) affects the MePD structural integrity at the same time that impairs male mating behavior. At the cellular level, dendritic spines modulate excitatory synaptic transmission, strength, and plasticity. Here, we describe the effect of GDX on the number and shape of dendritic spines in the right and left MePD using confocal microscopy and 3D image reconstruction. Age‐matched adult rats were intact (n = 6), submitted to a sham procedure (n = 4) or castrated and studied 90 days after GDX (n = 5). The MePD neurons have a density of 1.1 spines/dendritic μm composed of thin, mushroom‐like, stubby/wide, and few ramified or atypical spines. Irrespective of brain hemisphere, GDX decreased the dendritic spine density in the MePD, but induced different effects on each spine type. That is, compared to control groups, GDX reduced (i) the number (up to 50%) of thin, mushroom‐like, and ramified spines, and (ii) the size and the neck length of thin spines as well as the head diameter of ramified spines. Besides, GDX increased the number of stubby/wide and atypical spines (up to 140% and 400%, respectively). These data show that GDX promotes a cellular and synaptic reorganization in a spine‐specific manner in the MePD. By altering the number and shape of these connectional elements, GDX can affect the neural transmission and hinder the function of integrated brain circuitries in the male brain.
Identification and management of elder physical abuse in the routine of dentistry – a systematic review
Authors: Silva Luanderson O. , Souza‐Silva Bianca N. , de Alcântara Rodrigues José Lucas , Rigo Lilian , Cericato Graziela O. , Franco Ademir , Paranhos Luiz R. 
Published: November 2016

ObjectiveTo perform a systematic search in the literature in order to verify whether the dentists are able to identify and manage cases elder physical abuse.BackgroundDentists may play an important legal role contributing to the management of abused patients through the identification of injuries in their face, head and neck.Materials and methodsThe present systematic review was performed following the PRISMA Statement and was registered in the PROSPERO database. A search was conducted in the following electronic databases: PubMed, LILACS, SciELO, Embase, Web of Science, OpenGrey, Google Scholar. Specifically, the last two databases were used to search the ‘grey literature’. The research question was based on the PVO strategy for systematic exploratory review. Two examiners determined the eligibility criteria for selecting the studies and performed all the research steps.ResultsThe initial search resulted in 842 studies, from which eight were considered eligible. Six studies used questionnaires to assess the perception, knowledge and attitudes of dentists towards the identification and management of cases of elder abuse, while two studies assessed this information through personal interviews. Two studies were rated as high quality, while six studies reached moderate quality. Male and female dentists were assessed separately in six studies. Only three studies specified the aggressor.ConclusionThe dentists revealed insufficient knowledge on elder abuse. Most of the dentists are not able to identify and manage these cases in the clinical routine.
Is There a Too‐Big‐to‐Fail Discount in Excess Returns on German Banks’ Stocks?
Authors: Nitschka Thomas 
Published: November 2016

AbstractSince the global financial crisis, German and other European banks’ stocks have underperformed compared with the overall euro‐area stock market. Does this observation reflect the explicit state guarantee for too‐big‐to‐fail (TBTF) banks? In that case, investors have an incentive to hold stocks of systemically important banks because they provide insurance against disaster risk through the state guarantee. Indeed, recent studies reveal a TBTF discount in large US banks’ stock returns. Does this finding pertain to German (representing continental European) banks too? The main results of this paper suggest that it does. Risk‐adjusted returns on a German bank stock index were negative in the period from 1973 to 2014. The key driver of this finding is an unanticipated, adverse shock to the German banking sector at the beginning of the global financial crisis. This shock increased the probability of a bank default and thus the insurance value of government support.
Association between dental caries experience and sense of coherence among adolescents and mothers
Authors: Lage Carolina Freitas , Fulgencio Livia Bonfim , Corrêa‐Faria Patricia , Serra‐Negra Junia Maria , Paiva Saul Martins , Pordeus Isabela Almeida 
Published: November 2016

BackgroundSense of coherence (SOC) is associated with oral health.AimInvestigate associations between dental caries experience and SOC among mothers and adolescents.DesignA cross‐sectional study was conducted with 1195 adolescents and their mothers. Data were collected through a questionnaire, the short version of the SOC and oral clinical examinations. The data were statistically analyzed using bivariate analysis, Poisson regression models with robust variance, and Spearman's correlation coefficient.ResultsThe prevalence of dental caries experience was 41.8%. A moderate correlation was found between the SOC of mothers and adolescents (r = 0.563; P < 0.001). A higher mother's SOC (PR: 0.44; 95% CI: 0.36–0.53) and adolescent's SOC (PR: 0.46; 95% CI: 0.39–0.55) were protective factors against dental caries experience in the adolescents. The prevalence of dental caries experience was higher among adolescents with visible plaque (Model 1—PR: 1.77; 95% CI: 1.53–2.04; Model 2—PR: 1.59; 95% CI: 1.37–1.84) and those whose families were in a lower economic class (Model 1—PR: 1.56; 95% CI: 1.35–1.80; Model 2—PR: 1.57; 95% CI: 1.36–1.81).ConclusionDental caries in adolescents was associated with social determinants evaluated through the sense of coherence.
Investigation into the Physiological Significance of the Phytohormone Abscisic Acid in Perkinsus marinus, an Oyster Parasite Harboring a Nonphotosynthetic Plastid
Authors: Sakamoto Hirokazu , Suzuki Shigeo , Nagamune Kisaburo , Kita Kiyoshi , Matsuzaki Motomichi 
Published: November 2016

AbstractSome organisms have retained plastids even after they have lost the ability to photosynthesize. Several studies of nonphotosynthetic plastids in apicomplexan parasites have shown that the isopentenyl pyrophosphate biosynthesis pathway in the organelle is essential for their survival. A phytohormone, abscisic acid, one of several compounds biosynthesized from isopentenyl pyrophosphate, regulates the parasite cell cycle. Thus, it is possible that the phytohormone is universally crucial, even in nonphotosynthetic plastids. Here, we examined this possibility using the oyster parasite Perkinsus marinus, which is a plastid‐harboring cousin of apicomplexan parasites and has independently lost photosynthetic ability. Fluridone, an inhibitor of abscisic acid biosynthesis, blocked parasite growth and induced cell clustering. Nevertheless, abscisic acid and its intermediate carotenoids did not affect parasite growth or rescue the parasite from inhibition. Moreover, abscisic acid was not detected from the parasite using liquid chromatography mass spectrometry. Our findings show that abscisic acid does not play any significant roles in P. marinus.
Better Nurse Autonomy Decreases the Odds of 30‐Day Mortality and Failure to Rescue
Authors: Rao Aditi D. , Kumar Aparna , McHugh Matthew 
Published: November 2016

AbstractResearch PurposeAutonomy is essential to professional nursing practice and is a core component of good nurse work environments. The primary objective of this study was to examine the relationship between nurse autonomy and 30‐day mortality and failure to rescue (FTR) in a hospitalized surgical population.Study DesignThis study was a secondary analysis of cross‐sectional data. It included data from three sources: patient discharge data from state administrative databases, a survey of nurses from four states, and the American Hospital Association annual survey from 2006–2007.MethodsSurvey responses from 20,684 staff nurses across 570 hospitals were aggregated to the hospital level to assess autonomy measured by a standardized scale. Logistic regression models were used to estimate the relationship between nurse autonomy and 30‐day mortality and FTR. Patient comorbidities, surgery type, and other hospital characteristics were included as controls.FindingsGreater nurse autonomy at the hospital level was significantly associated with lower odds of 30‐day mortality and FTR for surgical patients even after accounting for patient risk and structural hospital characteristics. Each additional point on the nurse autonomy scale was associated with approximately 19% lower odds of 30‐day mortality (p < .001) and 17% lower odds of failure to rescue (p < .01).ConclusionsHospitals with lower levels of nurse autonomy place their surgical patients at an increased risk for mortality and FTR.Clinical RelevancePatients receiving care within institutions that promote high levels of nurse autonomy have a lower risk for death within 30 days and complications leading to death within 30 days. Hospitals can actively take steps to encourage nurse autonomy to positively influence patient outcomes.
Response to Karen Lebacqz and Stephen Palmquist
Authors: Green Ronald M. 
Published: November 2016

AbstractI respond here to the essays by Karen Lebacqz and Stephen Palmquist, beginning with my debt of gratitude to Lebacqz for her understanding of the methodological depth I try to bring to the analysis of bioethical issues. I further illustrate that observation here by reviewing the logic of my approach to the issue of wrongful life. At the same time, in connection with human genetic enhancement, I acknowledge that I may have not properly appreciated the seriousness of the problem of sin. To Palmquist's assertion that my criticisms of Kant's treatments of grace miss the way Kant has confined himself to being a philosophical (as opposed to biblical) theologian, I argue that Kant's problem lies instead in his poor application of his own compelling insights about the depths of human sinning. I close with an appreciation of Palmquist's observation of some important points of contact between Kant's understanding of sin and that of Kierkegaard.