bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Effect of Citrulline Malate Supplementation on Upper-Body Resistance Exercise Performance in Recreationally Resistance-Trained Men
Authors: Gonzalez Adam M. , Spitz Robert W. , Ghigiarelli Jamie J. , Sell Katie M. , Mangine Gerald T. 
Published: November 2017

Abstract
Gonzalez, AM, Spitz, RW, Ghigiarelli, JJ, Sell, KM, and Mangine, GT. Acute effect of citrulline malate supplementation on upper-body resistance exercise performance in recreationally resistance-trained men. J Strength Cond Res 32(11): 3088–3094, 2018—To investigate the effect of citrulline malate (CM) supplementation on upper-body resistance exercise performance, 12 recreationally resistance-trained men (21.4 ± 1.6 years; 163.0 ± 46.2 cm; 85.0 ± 12.4 kg) underwent 2 testing sessions administered in a randomized, double-blind fashion. During each visit, participants were provided either 8 g of CM or a placebo (PL) 40 minutes before beginning a standardized warm-up and initiating a barbell bench press resistance exercise protocol consisting of 5 sets of 15 repetitions at 75% 1 repetition maximum with 2-minute rest intervals. Participants were instructed to complete as many repetitions as possible until either reaching 15 repetitions or muscular failure. Total number of repetitions performed and power output were recorded for each set. Subjective measures of energy, focus, fatigue, and perceived exertion, along with muscle thickness of the triceps brachii, were assessed before and after exercise. Significant (p ≤ 0.05) main effects for time were observed for all variables except for subjective feelings of energy (p = 0.085). A group × time interaction (F = 2.86, p = 0.034, n
2 = 0.21) was observed for repetitions performed, where participants performed more (p = 0.015) repetitions on set 3 during PL (5.7 ± 1.2 repetitions) compared with CM (4.6 ± 1.2 repetitions). However, during set 4, participants tended (p = 0.089) to perform more repetitions during CM (4.8 ± 1.8 repetitions) compared with PL (4.3 ± 1.3 repetitions). No other differences were observed between trials. Supplementation with 8 g of CM 40 minutes before the barbell bench press resistance exercise protocol did not increase exercise performance, augment the muscle swelling response to training, or alter subjective measures of focus, energy, and fatigue in recreationally resistance-trained men.
Phenotype–genotype spectrum of AAA syndrome from Western India and systematic review of literature
Authors: Patt Hiren , Koehler Katrin , Lodha Sailesh , Jadhav Swati , Yerawar Chaitanya , Huebner Angela , Thakkar Kunal , Arya Sneha , Nair Sandhya , Goroshi Manjunath , Ganesh Hosahithlu , Sarathi Vijaya , Lila Anurag , Bandgar Tushar , Shah Nalini 
Published: November 2017

Objective
To study genotype–phenotype spectrum of triple A syndrome (TAS).

Methods
Retrospective chart analysis of Indian TAS patients (cohort 1, n = 8) and review of genotyped TAS cases reported in world literature (cohort 2, n = 133, 68 publications).

Results
Median age at presentation was 4.75 years (range: 4–10) and 5 years (range: 1–42) for cohorts 1 and 2, respectively. Alacrima, adrenal insufficiency (AI), achalasia and neurological dysfunction (ND) were seen in 8/8, 8/8, 7/8 and 4/8 patients in cohort 1, and in 99, 91, 93 and 79% patients in cohort 2, respectively. In both cohorts, alacrima was present since birth while AI and achalasia manifested before ND. Mineralocorticoid deficiency (MC) was uncommon (absent in cohort 1, 12.5% in cohort 2). In cohort 1, splice-site mutation in exon 1 (p.G14Vfs*45) was commonest, followed by a deletion in exon 8 (p.S255Vfs*36). Out of 65 mutations in cohort 2, 14 were recurrent and five exhibited regional clustering. AI was more prevalent, more often a presenting feature, and was diagnosed at younger age in T group (those with truncating mutations) as compared to NT (non-truncating mutations) group. ND was more prevalent, more common a presenting feature, with later age at onset in NT as compared to T group.

Conclusion
Clinical profile of our patients is similar to that of patients worldwide. Alacrima is the earliest and most consistent finding. MC deficiency is uncommon. Some recurrent mutations show regional clustering. p.G14Vfs*45 and p.S255Vfs*36 account for majority of AAAS mutations in our cohort. Phenotype of T group differs from that of NT group and merits future research.
Nitrative DNA damage in cultured macrophages exposed to indium oxide
Authors: Afroz Tahmina , Hiraku Yusuke , Ma Ning , Ahmed Sharif , Oikawa Shinji , Kawanishi Shosuke , Murata Mariko 
Published: November 2017

Abstract

Objectives
Indium compounds are used in manufacturing displays of mobile phones and televisions. However, these materials cause interstitial pneumonia in exposed workers. Animal experiments demonstrated that indium compounds caused lung cancer. Chronic inflammation is considered to play a role in lung carcinogenesis and fibrosis induced by particulate matters. 8-Nitroguanine (8-nitroG) is a mutagenic DNA lesion formed during inflammation and may participate in carcinogenesis. To clarify the mechanism of carcinogenesis, we examined 8-nitroG formation in indium-exposed cultured cells.

Methods
We treated RAW 264.7 mouse macrophages with indium oxide (In2O3) nanoparticles (primary diameter : 30-50 nm), and performed fluorescent immunocytochemistry to detect 8nitroG. The extent of 8-nitroG formation was evaluated by quantitative image analysis. We measured the amount of nitric oxide (NO) in the culture supernatant of In2O3-treated cells by the Griess method. We also examined the effects of inhibitors of inducible NO synthase (iNOS) and endocytosis on In2O3-induced 8-nitroG formation.

Results
In2O3 significantly increased the intensity of 8-nitroG formation in RAW 264.7 cells in a dose-dependent manner. In2O3-induced 8-nitroG formation was observed at 2 h and further increased at 4 h, and the amount of NO released from In2O3-exposed cells was significantly increased at 2-4 h compared with the control. 8-NitroG formation was suppressed by 1400W (an iNOS inhibitor), methyl-β-cyclodextrin and monodansylcadaverine (inhibitors of caveolae-and clathrin-mediated endocytosis, respectively).

Conclusions
These results suggest that endocytosis and NO generation participate in indium-induced 8-nitroG formation. NO released from indium-exposed inflammatory cells may induce DNA damage in adjacent lung epithelial cells and contribute to carcinogenesis.
Intubation Failure During Gastroscopy: Incidence, Predictors and Follow-Up Findings
Authors: Siau Keith , Li Jessie , Fisher Neil C. , Mulder Chris J.J. , Ishaq Sauid 
Published: November 2017

Background: Intubation failure (IF) occurs when an endoscopist is unable to progress via the oropharynx into the upper oesophagus. Aim: To assess incidence and aetiology of IF and predictors of structural pharyngeal abnormalities in patients with IF.Methods: All gastroscopies (n=26,130) performed in our centre, between August 2010 and August 2016 were retrospectively reviewed. Barium radiology and repeat gastroscopy findings were evaluated for structural causes of IF. Patients were categorised into ‘failure to tolerate’ and ‘failure to progress’ based on endoscopy reports.Results: The incidence of IF was 0.95%. Rates of IF varied with endoscopist specialty (p=0.021), but not with patient age, sex or sedation dose. Among cases of IF, structural pharyngeal abnormalities were detected on barium radiology in 28.9%, consisting of cricopharyngeal hypertrophy and/or Zenker’s diverticulum in 73.2%. ‘Failure to progress’ predicted pharyngeal pathology in 55.6%. Predictors of structural causes on barium radiology following IF included: age ≥65 (OR 4.0, 95% CI: 1.8-8.9, p<0.001); indication of dysphagia (OR 5.5, 95% CI: 2.5-11.8, p<0.001), and failure of endoscopic progression (OR 5.2, 95% CI: 2.3-12.0, p<0.001).Conclusion: Patients with IF should be investigated owing to the high risk of underlying pathology, particularly if associated with age ≥65, dysphagia, and failure of endoscopic progression. We propose that IF rates of <1% could be used as a quality indicator in gastroscopy. .Abbreviations: ASGE: Association for Gastrointestinal Endoscopy; CI: Confidence interval; CP: Cricopharyngeus; CPH: Cricopharyngeal hypertrophy; FESD: Flexible endoscopic septum division; GRS: Global rating scale; IF: Intubation failure; JAG: Joint Advisory Group for gastrointestinal endoscopy; NME: Non-medical endoscopist; OR: Odds ratio; SI: Successful intubation; ZD: Zenker’s diverticulum.
Rare Primary Esophageal Paget’s Disease Diagnosed on a Large Bloc Specimen Obtained by Endoscopic Mucosal Resection
Authors: Mori Hirohito , Ayaki Maki , Kobara Hideki , Goda Yasuhiro , Nishiyama Noriko , Masaki Tsutomu 
Published: November 2017

Primary esophageal Paget’s disease is rare. Only a few case reports have described the intraepithelial papillary capillary loop (IPCL) pattern obtained by magnified Narrow Band Imaging (M-NBI) endoscopy in this rare pathology. This report highlights the usefulness of M-NBI and the successful diagnosis using a large bloc specimen obtained by endoscopic mucosal resection with the cap method (EMR−c). A 53-year-old man was referred to endoscopic examination for dysphagia. The endoscopic image revealed a ring-shaped scarring of the esophagus suggestive for eosinophilic esophagitis. The IPCL pattern by M-NBI endoscopy showed an inflammatory pattern, and the entire epithelium of the esophagus was not stained by Lugol iodine spraying. Based on six biopsies randomly performed, a poorly differentiated adenocarcinoma was diagnosed. Since the M-NBI pattern and the histology were completely different, EMR−c was performed to obtain large bloc specimens for a more detailed diagnosis. The pathological findings revealed extensive Paget’s cells infiltration into the epithelium and multifocal invasion from the mucosa to the submucosal layer with adenocarcinoma. In conclusion, a large bloc specimen by EMR-c might be more useful than a small biopsy for an accurate diagnosis of the rare esophageal Paget’s disease.Key words: – – .Abbreviations: EMR−c: endoscopic mucosal resection with cap method; IPCL: intraepithelial papillary capillary loop; LVLs: Lugol-voiding lesions; M-NBI: magnified Narrow Band Imaging; PET-CT: Positron-Emission Tomography and Computed Tomography.
Error compensation in NC machine tools
Authors: Rahou Mohamed , Sebaa Fethi , Cheikh Abdelmadjid , Benmansour Sid Ahmed 
Published: November 2017

This work contributes to the development of new approaches to tolerancing for machining using a machine tool with digital control. Our research is focused in two directions. First, it focuses on the manufacturing tolerances. The aim was to establish procedures for validating ranges of light manufacturing dispersions, manufacturing errors and machine tools with digital control, and cover various types of critical tolerances targeted. The second deals with design tolerances, for which we proposed a method for calculating functional tolerances.
Keywords: Errors, tolerance, manufacturing.
Message from editor
Authors: Ibrahim Dogan 
Published: November 2017

Dear Readers,

It is a great honor for us to publish Volume 7, Issue 1 of Global Journal of Computer Sciences: Theory and Research.

Global Journal of Computer Sciences: Theory and Research (GJCS) is an international online journal for scientists and professionals involved in all aspects of computer sciences. This journal serves as an international platform that fosters theoretical and practical issues and new applications for all scientists and professionals from the field of computer sciences including original research and innovative applications from all parts of the world.

Aim of this issue is to give the researchers an opportunity to share the results of their academic studies. There are different research topics discussed in the articles. For example, Musa Peker, Ali Sasar, Osman Ozkaraca and Gurbuz Akcay examined estimation of HbA1c value using artificial neural networks. Fatih Tekmen and Ozgun Tanriover provided an an assessment of a government website by focusing on website usability evaluation with quickly applicable guidelines. In addition, Abdallah Tubaishat and Sara Sumaidaa carried out research on implementation guidelines for green data centres. Mohamed Rahou, Fethi Sebaa and Abdelmadjid Cheikh Sid Ahmed Benmansour discussed error compensation in NC machine tools. Amel Ourici, Wafa Tourab and Merabet Leila examined direct control of active and reactive power of a doubly fed induction machine. Sekhane Hocine and Labed Djamel investigated standard IEEE test systems 57-bus and Algerian 59-bus together and they concluded that the results of power flow compared with the popular MATPOWER software environment show the exactitude of our code calculation, and the enhancement of voltage profile, especially in buses where STATCOM is placed. Finally, Cigdem Bakir proposed a speech recognition system for Turkish language with hybrid method.

A total number of ten (10) manuscripts were submitted for this issue and each paper has been subjected to double-blind peer review process by the reviewers specialized in the related field. At the end of the review process, a total number of seven (7) high quality research papers were selected and accepted for publication.
We present many thanks to all the contributors who helped us to publish this issue.
Best regards
Prof. Dr. Dogan Ibrahim
Editor â€“ in Chief
El mercadeo de lugares como herramienta estratégica para el municipio de Viotá (Cundinamarca, Colombia)
Authors: Rodríguez González Adriana Rocío , Quijano Omar Guiovanni 
Published: November 2017

Rev.esc.adm.neg
Este artículo, de carácter descriptivo, relata de manera concisa los resultados de investigación obtenidos a partir del estudio realizado en el municipio de Viotá (Cundinamarca, Colombia), en el cual se analizaron las posibles fortalezas y oportunidades de este para la propuesta, el diseño y la creación de un plan de marketing a partir de la valoración y admiración de su historia, arquitectura y paisajes mediante el diseño y la consolidación de una marca ciudad para el municipio que centra todas las características potenciales que posee, con el fin de consolidar y promocionar a Viotá como un destino turístico en el ámbito nacional.
Relaciones entre formación disciplinar, concepciones sobre el aprendizaje y uso de estrategias metacognitivas en estudiantes universitarios de profesorado
Authors: García María-Basilisa , Vilanova Silvia-Lucía , Señoriño Orlanda-Angélica , Medel Gisele-Anahí , Natal Marcela 
Published: November 2017

Detrás de las acciones y estrategias de las personas para aprender o enseñar, existe un cuerpo teórico no explícito, que se configura a partir de un conjunto de supuestos coherentes o incoherentes entre sí, en función de la relación que exista entre lo que el sujeto dice y lo que hace. Estas representaciones implícitas surgen no sólo de la educación formal recibida, sino de la propia historia educativa de cada sujeto y, en el caso de los docentes, orientan de un modo u otro su práctica, tal como lo indican numerosas investigaciones sobre el tema. En este trabajo se analizan las concepciones sobre el aprendizaje y la utilización de estrategias metacognitivas de dos grupos de estudiantes universitarios de profesorado, provenientes de distintas áreas disciplinares: ciencias humanas y ciencias exactas. Los resultados muestran dependencia de las concepciones de aprendizaje con respecto al dominio de formación disciplinar, situación que se da sólo parcialmente en el caso de la utilización de estrategias metacognitivas.
Moldes electroformados para la Industria de los plásticos
Authors: De Laverde Traductora Ilse Koenig 
Published: November 2017

Se describe a la galvanoplastia como uno los métodos clásicos, para la fabricación de moldes en las áreas de la transformación de los plásticos, teniendo en cuenta sus principios, materiales y aplicaciones típicas de moldes fabricados por este método.
Manual de mantenimiento. Parte IX: Reparaciones mayores. Almacén de mantenimiento
Authors: Botero Camilo 
Published: November 2017

Cuando se decide que una máquina debe someterse a una reparación mayor, se deben dirigir todos los recursos técnicos administrativos hacia ella, con el fin de obtener una reparación rápida y eficiente y, disminuir el tiempo de parada de la máquina y evitar el incumplimiento con los clientes. Se describe los pasos a seguir en una reparación mayor de una máquina y los requerimientos necesarios para hacer del almacén de mantenimiento eficiente.
In vitro effect of blood cell counts on multiple-electrode impedance aggregometry in dogs
Authors: Nash Katherine J. , Bacek Lenore M. , Christopherson Pete W. , Spangler Elizabeth A. 
Published: November 2017

Abstract
OBJECTIVE To assess the effect of decreased platelet and WBC counts on platelet aggregation as measured by a multiple-electrode impedance aggregometer in dogs.
ANIMALS 24 healthy dogs.
PROCEDURES From each dog, 9 mL of blood was collected into a 10-mL syringe that contained 1 mL of 4% sodium citrate solution to yield a 10-mL sample with a 1:9 citrate-to-blood ratio. Each sample was then divided into unmanipulated and manipulated aliquots with progressively depleted buffy-coat fractions such that 2 to 3 blood samples were evaluated per dog. The Hct for manipulated aliquots was adjusted with autologous plasma so that it was within 2% of the Hct for the unmanipulated aliquot for each dog. All samples were analyzed in duplicate with a multiple-electrode impedance aggregometer following the addition of ADP as a platelet agonist. The respective effects of platelet count, plateletcrit, Hct, and WBC count on platelet aggregation area under the curve (AUC), aggregation, and velocity were analyzed with linear mixed models.
RESULTS WBC count was positively associated with platelet AUC, aggregation, and velocity; blood samples with leukopenia had a lower AUC, aggregation, and velocity than samples with WBC counts within the reference range. Platelet count, plateletcrit, and Hct did not have an independent effect on AUC, aggregation, or velocity.
CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that WBC count was positively associated with platelet aggregation when ADP was used to activate canine blood samples for impedance aggregometry. That finding may be clinically relevant and needs to be confirmed by in vivo studies.
Analysis of the association between density of Helicobacter spp and gastric lesions in dogs
Authors: Suárez-Esquivel Marcela , Alfaro-Alarcón Alejandro , Guzmán-Verri Caterina , Barquero-Calvo Elías 
Published: November 2017

Abstract
OBJECTIVE To evaluate the correlation between the density of native gastric Helicobacter spp and the presence of gastric lesions in dogs.
ANIMALS 80 dogs of various breeds, sexes, and ages.
PROCEDURES Gastroscopic and histologic examinations were performed for all dogs. Helicobacter spp were detected by combining evaluation of urease activity and results of bacteriologic culture, microscopic observation, and a 16S rRNA PCR assay. The density of Helicobacter-like organisms was evaluated with light microscopy by use of Warthin-Starry modified stain. Correlations were evaluated by use of the Spearman correlation analysis.
RESULTS Gastritis was found in 55 of 80 dogs and classified as mild (n = 31), moderate (16), or severe (8). Of these 55 dogs, only 8 had clinical signs. Histologic examination revealed some degree of lymphocytic-plasmacytic infiltrate, mild eosinophilia, and neutrophilic inflammation in the lamina propria. Seventy-six dogs had positive results for Helicobacter spp. Helicobacter pylori DNA was not detected. Low density and homogeneous distribution of Helicobacter spp were observed in all gastric zones.
CONCLUSIONS AND CLINICAL RELEVANCE A significant correlation between density of Helicobacter spp and gastroscopic or histologic lesions was not detected. These findings supported the contention that there is no correlation between general Helicobacter spp density or numbers and gastritis in dogs.
Effect of meloxicam administration on movement, feeding, and drinking behaviors of transported and nontransported cattle
Authors: Capik Sarah F. , White Brad J. , Larson Robert L. , Van Engen Nicholas , Coetzee Johann F. 
Published: November 2017

Abstract
OBJECTIVE To evaluate the effects of meloxicam on movement, feeding, and drinking behaviors of transported and nontransported cattle.
ANIMALS 100 crossbred beef steers.
PROCEDURES During experiment 1 of a 2-experiment study, calves from a livestock auction received meloxicam (1 mg/kg, PO; n = 50) or a lactose placebo (1 capsule/calf; 50; control), then calves were transported approximately 1,000 km overnight to a feedlot, where they were instrumented with a real-time location-monitoring ear tag, placed in randomly assigned pens (n = 5 pens/treatment), and monitored for 21 days. During experiment 2, calves in pens were administered the treatment opposite that of experiment 1, returned to their pens without undergoing transportation, and monitored for another 21 days. For each experiment, mean daily distance traveled and percentage time spent near feed (PNF) and water (PNW) were calculated on a pen basis and compared between treatments.
RESULTS During experiment 1, mean daily distance traveled, PNF, and PNW did not differ significantly between meloxicam-treated and control calves; however, all 3 behaviors varied significantly by day. During experiment 2, although mean distance traveled was significantly associated with the interaction between day and treatment, it did not differ significantly between meloxicam-treated and control calves within any specific day. Mean PNF and PNW were significantly associated with day only, although no pattern in that effect was evident.
CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that a single dose of meloxicam prior to transportation did not significantly affect the behaviors of transported and nontransported calves.
MENGUKUR URBAN HEAT ISLAND MENGGUNAKAN PENGINDERAAN JAUH, KASUS DI KOTA YOGYAKARTA
Authors: Fawzi Nurul Ihsan 
Published: November 2017

<p>Peningkatan suhu di kawasan perkotaan adalah salah satu dampak dari urbanisasi. Fenomena <em>Urban Heat Island</em> (UHI) merupakan salah satu akibat yang dihasilkan akibat peningkatan suhu tersebut. Diperlukan upaya untuk menilai perubahan suhu apakah dapat berbahaya bagi manusia atau tidak. Melalui pengukuran UHI, pengaruh pembangunan kota terhadap peningkatan suhu dapat diukur. Tujuan penelitian ini adalah untuk memberikan panduan ilmiah tentang perolehan intensitas dan distribusi UHI menggunakan teknik penginderaan jauh. Studi kasus yang dilakukan berada di Kota Yogyakarta, Daerah Istimewa Yogyakarta. Citra penginderaan jauh yang digunakan adalah citra Landsat 8 perekaman tanggal 24 Juni 2013, <em>path/row</em> 120/65. Metode ekstraksi suhu permukaan menggunakan inversi persamaan Planck dengan koreksi emisivitas dan atmosfer menggunakan <em>radiative transfer equation</em>. Hasil pengolahan didapatkan intensitas UHI sebesar <em>±</em>2,5<sup>o</sup>C pada Kota Yogyakarta dan intensitas UHI sebesar <em>±</em>3,23<sup>o</sup>C pada area yang diperluas dengan buffer 1 km dari batas Kota Yogyakarta. Hal ini menunjukkan bahwa pemilihan area penelitian untuk analisis UHI menjadi penting karena mempengaruhi nilai intensitas UHI dan distribusi UHI. Ditemukan kawasan Malioboro dan sekitarnya berpotensi kuat terjadi UHI, sehingga perlu upaya mitigasi UHI pada kawasan tersebut. Pengukuran UHI menggunakan penginderaan jauh dipengaruhi oleh hal-hal yang berkaitan dengan sistem penginderaan jauh, seperti validasi dan akurasi hasil estimasi, pengaruh atmosfer, dan perbedaan waktu intensitas puncak UHI. Metode perolehan UHI dalam penelitian ini dapat menjadi panduan ilmiah yang digunakan untuk dasar evaluasi pembangunan perkotaan untuk lebih baik. </p>