bluuebunny/crossref_metadata_2025_split huggingface dataset:
Community Participation in Village Development Planning
Authors: Nadhiro Riza Ayu , Choiriyah Ilmi Usrotin 
Published: September 2024

This study investigates community participation in planning physical development in Suko Village, Sidoarjo District, Indonesia. Employing descriptive qualitative research, the study utilizes interviews, observation, and documentation, with purposive sampling techniques. The results reveal a five-stage model of community involvement: (1) establishment of the Suko Village RPJM drafting team, (2) hamlet meetings, (3) community participation in village development planning, (4) preparation of plans and development plans for community involvement (BPD), and (5) establishment of the Village RPJM, represented by the BPD. This study contributes to the understanding of community participation in development planning and offers insights for enhancing community involvement in urban and rural settings.
Highlight :

Five-stage model: Identifies key stages for community involvement in physical development planning.
Purposive sampling: Ensures diverse stakeholder voices are heard during planning process.
BPD representation: Empowers village representatives to champion community needs in development plans.

Keywords: community participation, physical development, Suko Village, Indonesia, qualitative research
Distancing alters the controllability of emotional states by affecting both intrinsic stability and extrinsic sensitivity
Authors: Malamud Jolanda , Huys Quentin 
Published: September 2024

Abstract

Background: Emotion regulation strategies such as distancing are a core component of many evidence-based, effective psychotherapeutic interventions. They allow individuals to exert more 'control' over their emotional state. However, objectively disentangling how emotion regulation increases control has been difficult for reasons including a lack of a coherent theoretical framework for emotion control and insufficient experimental control over external inputs. Here, we apply a well-established theoretical framework for controllability to a tightly controlled experimental setup to examine the computational mechanisms by which emotion regulation interventions enhance emotional controllability.
Methods: 109 participants were randomized to either a short emotion regulation intervention (distancing) or a control intervention. Both before and after the intervention, participants reported their emotional state along five dimensions repeatedly while watching a series of short, standardized, emotional video clips. A Kalman Filter was used to quantify how multidimensional emotional states changed with video inputs. The consequences of the emotion regulation intervention were examined by Bayesian model comparison, comparing models allowing for a change in intrinsic dynamics and/or input weights. Controllability was quantified using the controllability Gramian.
Results: The Kalman filter captured participants' emotional trajectories, showing that emotional states were affected by the emotional videos; persisted; and interacted with each other. The distancing strategy made emotional states less externally controllable. It did so by altering two aspects of the dynamical system: by stabilizing specific emotional patterns and by reducing the impact of the external video clips.
Conclusions: Our study used a novel approach to examine emotion regulation, finding that a brief distancing intervention increased perceived emotion control by reducing how much external stimuli can control emotional states. This is due to both an increase in the intrinsic stability of certain emotional states; and a reduction of the sensitivity to certain extrinsic affective stimuli.
Bridging the Gap Between GPDR and Software Development: The MATERIALIST Framework
Authors: Saltarella Marco , Desolda Giuseppe , Esposito Andrea , Greco Francesco , Lanzilotti Rosa 
Published: September 2024

Abstract

As software production evolves, privacy is becoming an increasingly important consideration. This is especially true as national and supranational regulations, such as GDPR, require privacy as a mandatory aspect of software development. However, challenges such as a lack of knowledge about privacy and data protection regulations hinder the adoption of effective and compliant privacy implementation mechanisms. To address this issue, this article presents MATERIALIST, a methodological and technological framework that supports stakeholders involved in a software development lifecycle in including GDPR in their activities. Specifically, it provides design patterns that can be selected starting from GDPR articles, code vulnerabilities, and software lifecycle phases. The framework aims to facilitate the adoption of appropriate privacy implementation mechanisms in the software development lifecycle, thereby improving software quality.
WITHDRAWN: Development and Validation of an Integrated Traditional Chinese Medicine and Western Medicine Early Screening Model for Coronary Heart Disease in the Community of Tianjin, China: A Simple and Practical Risk Model for Community Physicians
Authors: yang ji , ZHANG Yao , GAO Shengwei , zhao Yingqiang 
Published: September 2024

Abstract

The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Identifying and integrating consumer-prioritised topics and outcomes in clinical practice guidelines on managing kidney stones
Authors: Tunnicliffe David J , Wickham Ieuan , Jauré Allison , Johnston Brydee , Mallett Andrew J , Mullan Adam , Lloyd Lyn , Scholes-Roberston Nicole , Hassan Hicham Cheikh , Jose Matthew , Lee Vincent , See Emily , Boag Jane , Coolican Helen , Cullen Vanessa , Fortnum Debbie , Jun Min , Krishnasamy Rathika , Lambert Kelly , Craig Jonathan , Light Casey , Nguyen Thu , Scuderi Carla , Viecelli Andrea 
Published: September 2024

Abstract

Aim
The prevention and management of recurrent kidney stones can be challenging and requires patients to modify their diet and daily rountines that impact their quality of life. Our study aims to describe the process of integrating consumer-prioritised topics and outcomes in guidelines on kidney stones to ensure patient relevance.
Methods
Two workshops were convened in Aotearoa New Zealand with people with kidney stones invited to identify topics and outcomes for inclusion in the guidelines. Flipcharts and transcripts were analysed thematically to identify the reasons for participants’ choices.
Results
The topics identified by the twenty-eight participants included education on nutrition, better diagnosis, and individualised nutritional and pharmacological management. Pain, equity of access, anxiety about recurrence, and life participation were identified as important outcomes to be included. Four themes (and subthemes) underpinning priorities were: unresolvable debilitating pain (complexity of exctruciating acute episodic pain, inadequacy of pain relief medication, frustrated by stigma associated with opioids), dissatisfied at delayed access to care (prolonged difficulties in diagnosis, struggling to obtain individualised care), inadequate knowledge to enable self-management (insufficient information on kidney stones, conflicting nutrition advice, cultural deficit), and limiting life participation (restricting life choices, psychological burden of kidney stones).
Conclusions
Participants identified topics that would support symptom management to improve quality of life and reduce the burden on families. Guidelines should provide essential, consistent and clear guidance, particularly on nutrition, to support self-management. Incoporating consumer priorities in guidelines can help to support decision-making and patient-centred care in kidney stones.
Prevalence, associated factors and impact of vitamin B12 deficiency in elderly medical inpatients
Authors: Papakitsou Ioanna , Papazachariou Andria , Filippatos Theodosios 
Published: September 2024

Abstract

Methods
This retrospective cohort study investigates the prevalence of vitamin B12 deficiency, the associated factors and its relation to frailty and functional status. Data were collected from elderly inpatients (≥ 65 years) sequentially admitted to the Internal Medicine Department of a tertiary university hospital. Clinical and laboratory characteristics, including age, gender, somatometric data, cause of admission, past medical history, chronic medication use, and laboratory tests, were recorded. Frailty and functional status were assessed using the Fried Frailty Scale (FFS), Clinical Frailty Scale (CFS), Barthel Index, and Katz Index. Vitamin B12 levels were categorised as deficient (< 200 pg/ml), borderline (200–300 pg/ml), and normal (> 300 pg/ml).
Results
A total of 961 patients were included; the prevalence of vitamin B12 deficiency was found in 9.1%, while 17.3% of the sample had borderline levels. Multivariate analysis identified polypharmacy (≥5 drugs), low albumin levels/GNRI, and nursing home residency as independent factors associated with low B12 levels. Multivariate analyses showed that B12 deficiency was significantly associated with higher frailty rates and lower functional status.
Conclusion
Vitamin B12 deficiency is prevalent among hospitalized elderly patients and is significantly associated with increased frailty and reduced functional status. These findings underscore the importance of routine screening for B12 deficiency in this vulnerable population to improve clinical outcomes and quality of life.
Relationships among premonitory urges, tics, and quality of life in drug-naïve children with tic disorders: A mediation analysis of a Chinese sample
Authors: Wang Xianbin , Xu Hui , Li Yanlin , Hu Shujin , Yang Kai , Zhang Wenyan , Jiang Zhongliang , Cui Yonghua , Li Ying 
Published: September 2024

Abstract

Purpose
Premonitory urges (PUs) are a growing area of interest for research on tic disorders. Understanding the contributions of urges to quality of life (QoL) is important. This study explores the relationships among PUs, tic severity, and QoL in individuals with tic disorders (TDs).
Methods
Clinical data were collected from drug-naïve TD patients aged 6–16 years using the Yale Global Tic Severity Scale (YGTSS), the Premonitory Urge to Tic Scale (PUTS), and the Tourette-Quality of Life Scale (GTS-QOL). Patients were categorized into PU (PUTS > 9) and non-PU (NPU, PUTS = 9) groups. Logistic regression was used to analyze the influence of age and sex on the presence of PUs. Correlation and mediation analyses were performed.
Results
Among 1015 patients with PU and 259 without PU, significant differences (p < 0.05) were found in age, YGTSS scores, and overall GTS-QOL scores and its factors such as obsessive‒compulsive and psychological factors. No significant sex differences were observed (p = 0.291). Age was a significant predictor of PU presence (OR = 1.111, p < 0.001). Mediation analysis revealed that tic severity significantly mediated (p < 0.05) the relationship between PU and overall QoL, and this effect was evident across all YGTSS subscales.
Conclusions
PUs incidence in TD increases with age, correlating with higher tic severity and lower QoL. Tic severity mediates the PU-QoL relationship, but since the direct effect of PUs on QoL is the main factor, improving QoL requires greater attention to PUs over tic symptoms.
Correlation between pelvic bone marrow dose volume parameters and acute hematologic toxicity in neoadjuvant intensity-modulated radiotherapy for locally advanced rectal cancer
Authors: Huang Sicheng , Wang Gang , Wang Wenling , Wu Songyou , Li Xiaokai , Li Yun , Jiang Guangyi 
Published: September 2024

Abstract

Objective
To explore the correlation between pelvic bone marrow dose volume parameters (Vx) and acute haematological toxicity (HT) in patients undergoing neoadjuvant intensity- modulated radiotherapy for locally advanced rectal cancer(LARC), and to provide clinical data to reduce the risk of radiotherapy-associated HT and to optimise radiotherapy planning.
Methods
Seventy-five patients with LARC who underwent neoadjuvant concurrent radiotherapy (CCRT) from October 2019 to November 2023 at the Affiliated Cancer Hospital of Guizhou Medical University were retrospectively analysed. All patients underwent 5-field intensity- modulated radiotherapy (IMRT) with a prescribed dose of 45-50.4 Gy/25–28 times in the planned target (PTV). Simultaneous capecitabine or 5-fluorouracil (5-Fu) chemotherapy was delivered during radiotherapy. Acute HT during radiotherapy was assessed according to the National Cancer Institute Common Toxicity Criteria Version 5.0 (NCI-CTC.V5.0). Logistic regression analyses were used to assess the relationship between the dose-volume of bone marrow in the pelvis (Vx of hip, sacrum, and femur) and acute HT, and the non-linear relationship and threshold effect between the two were further analysed using the generalised additive model (GAM) and segmental regression.
Results
Multifactorial logistic regression analysis showed that there was a significant correlation between total pelvic bone marrow irradiated volume (TV) and coxal bone marrow irradiated volume (CV) at low doses (V5, V10) and ≥ 2 degrees of leukocyte reduction and neutrophil reduction (P < 0.05).There was a significant negative correlation between low-dose (V5, V10, V15) sacral bone marrow irradiated volume (SV) and ≥ 2 degrees of leukocyte reduction (P < 0.05). Threshold effect analysis showed that there was a threshold effect of CV10 with both ≥ 2 degrees of leukopenia and neutropenia, with similar thresholds of 483–495 ml for both.
Conclusion
In neoadjuvant intensity-modulated radiotherapy for rectal cancer, CV is a better predictor of acute HT compared with TV. CV associated with acute HT is mainly concentrated at low dose levels (CV5, CV10, CV15). The threshold of 483 ml for CV10 can be used as a reference for reducing the risk of acute HT and optimising radiotherapy planning in pelvic radiotherapy.
Assessment of Selected Chickpea Accessions for Tolerance to Aluminium and Manganese Toxicities in Solution Culture and Pot Experiments
Authors: Langat Elkanah Kipkoech , Ndemo Richard Onwonga , Karuma Ann 
Published: September 2024

Abstract

A good understanding of existing variability in Mn and Al toxicity tolerance among chickpea accessions is required to tackle ion-induced toxicities through the use of tolerant accessions. This study sought to identify acid-tolerant accessions through hydroponic and pot experiments for promotion and adoption in acidic environments. About 26 accessions were screened in nutrient solutions containing 0, 15, and 60µM Al, and 2 and 150µM Mn concentrations, and in pot experiments of pH levels 4.5 and 6.5. The experiments were conducted in a glasshouse with temperatures averaging 17OC at night and 25OC during the day. Split plot designs with Al and Mn concentrations as the main plot factor and accessions as the sub-plot factor and replicated thrice were used. Relative tolerance index (RTI), relative root length (RRL), relative shoot length (RSL), relative root weight (RRW), and relative shoot weight (RSW) were used as indices for tolerance for Al, and RSL, RSW, and symptom scores for Mn. Accessions Saina 1, ICCVs 11514, 11519, 11504, 11316, and 07114 were consistently tolerant or moderately tolerant across all indices at 15µM Al. Chania 1, ICCVs 03305, 93954, 07313, 96329, and 97110 were sensitive. At 60µM Al, most accessions were sensitive across all indices. Pot RRL results correlated significantly (r = 0.8) with those from the hydroponic experiments at 15µM Al, with ICCV 11504, ICCV 11514, Saina 1, ICCV 07114, Chania 2, ICCV 11316, ICCV 00108, K036, Leldet 068, and ICCV 10515 being moderately tolerant. In screening for tolerance to Mn, ICCV 07313, 07101, 97128, 11514, Chania 2, and Saina 1 were tolerant. Pot RSL values correlated weakly (r = 0.1) with those of hydroponic experiments. In conclusion, ICCV 11514 and Saina 1 emerged as the accessions with moderate tolerance to soil acidic conditions
Case Report: Successful Multidisciplinary Management of Adult Embryonal Sarcoma of the Liver (AESL) Complicated by Pregnancy
Authors: Chang Yau-Ren , Chiang Chi-Yuan , Chen Jen-Shi , Chu Shih-Ming , Chen Tse-Ching , Wu Yu-Tung , Hsieh Chi-Hsun 
Published: September 2024

Abstract

Background
Adult embryonal sarcoma of the liver (AESL) is an exceptionally rare malignancy, accounting for less than 1% of primary hepatic tumors in adults. While typically diagnosed in the pediatric population, its occurrence in adults is extremely uncommon and often presents diagnostic and therapeutic challenges. AESL is characterized by aggressive behavior, rapid growth, and lacks well-established risk factors. The association between AESL and pregnancy is underexplored, with limited understanding of the underlying mechanisms.
Case presentation
A 29-year-old pregnant woman at 16 weeks of gestation presented with escalating right abdominal pain and an enlarging mass. Imaging revealed a sizable cystic liver mass, prompting thorough diagnostic evaluation. Laboratory tests and aspiration cytology were inconclusive, leading to decisive intervention with total right lobectomy and cholecystectomy. Pathological analysis confirmed AESL. The intricacies of managing therapeutic decisions during pregnancy called for a multidisciplinary approach. This included the collective expertise of hepatobiliary surgeons, obstetricians, neonatologists, and oncologists, and encompassed vigilant fetal monitoring alongside subsequent cesarean section. In the postpartum phase, the patient received chemotherapy without evidence of tumor recurrence at the two-year follow-up. Despite a short ICU stay for early infections, the infant showed no serious complications or developmental delays.
Conclusions
Our successful multidisciplinary treatment for AESL during pregnancy emphasizes the importance of tailored care and interdisciplinary collaboration. The positive outcome underscores the significance of individualized treatment for pregnant cancer patients, contributing valuable insights to the limited literature on AESL during pregnancy and showcasing the potential effectiveness of this approach.
A Physics-Informed Stochastic Model for Long-Term Correlation of Earthquakes
Authors: Taroni Matteo , Barani Simone , Zaccagnino Davide , Petrillo Giuseppe , Harris Pietro Artale 
Published: September 2024

Abstract

In this work, a simple physics-informed stochastic earthquake catalog simulator is presented for the modeling of long memory on a single fault (or crustal volume). The simulation combines the fundamental statistical laws of seismology (i.e., the Gutenberg-Richter law and the exponential distribution of inter-event times of spontaneous events) with two physical assumptions: 1) earthquake magnitudes are constrained by the amount of potential energy accumulated within the crustal volume at a given time, 2) existence of an upper boundary for stress on the fault. The consequence is a deviation from the conventional exponential inter-event distribution. We analyze a set of simulated catalogs to inspect long memory. We found that, depending on the relative proportion of energy accumulation and release, catalogs can exhibit complex patterns and long memory behavior. Despite its simplicity, our simulator can replicate the key features of seismic activity observed in real data, thus enabling a consistent physical interpretation.
Dermatoscopic Assessment of Nailfold Capillary Structures in Connective Tissue Diseases
Authors: Dogdu Murat , Altinyazar Hilmi Cevdet , Yilmaz Sema , Demirbas Abdullah , Diremsizoglu Esin 
Published: September 2024

Abstract

This study aimed to evaluate nailfold capillary abnormalities in patients with connective tissue diseases (CTDs) using a videodermatoscope and compare the findings with healthy controls. Seventy-two patients diagnosed with CTDs, including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), systemic sclerosis (SSc), primary Sjögren’s syndrome (SS), undifferentiated connective tissue disease (UCTD), and thirty-three healthy controls, were included. Capillary abnormalities such as enlarged capillaries, avascular areas, tortuous-twisted capillaries, ramified-bushy capillaries, and hemorrhages were assessed at magnifications of ×20, ×30, and ×40. The scleroderma pattern (SScP) was defined by the presence of two or more abnormalities in at least two nailfolds, with a revised SScP excluding tortuous-twisted capillaries. The standard SScP exhibited a sensitivity of 78.57% and a specificity of 96.97%. SScP was observed in 25% of rheumatoid arthritis (RA) cases, 42.9% of primary Sjögren's syndrome (SS) cases, and 57.1% of undifferentiated connective tissue disease (UCTD) cases, but none in primary RP or systemic lupus erythematosus (SLE) cases. The revised SScP showed a sensitivity of 64.29% and a specificity of 100%. It was found in 28.6% of primary SS cases and 42.9% of UCTD cases, but none in primary RP, SLE, or RA cases. One (3%) of healthy controls exhibited SScP, but none showed the revised SScP. There was no statistically significant difference in detecting tortuous-twisted capillaries between patients and healthy controls (p > 0.05). However, there was a significant difference in identifying the other four parameters (p < 0.05). Comparison of magnifications showed no significant difference between ×30 and ×40 (p > 0.05), but a significant difference between ×20 and ×40 in detecting tortuous-twisted capillaries (p < 0.05). No significant correlation was found between disease duration and capillaroscopic abnormalities. Videodermatoscopy is a reliable tool for evaluating nailfold capillaries in connective tissue disease (CTD) patients, with magnifications of ×30 and above providing the most detailed assessments. It effectively differentiates primary and secondary Raynaud's phenomenon and highlights the diagnostic value of capillaroscopy in identifying CTD-specific abnormalities, particularly in systemic sclerosis (SSc).