bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biopsychosocial factors associated with chronic low back pain disability in rural Nigeria: a population-based cross-sectional study
Authors: Igwesi-Chidobe Chinonso Nwamaka , Coker Bolaji , Onwasigwe Chika N , Sorinola Isaac O , Godfrey Emma L 
Published: September 2017

IntroductionMany people in Nigeria are living with disability due to chronic low back pain (CLBP), with the greatest burden accounted for by people living in rural Nigeria. However, factors associated with disability in rural Nigeria have not yet been established. We investigated the biomechanical and psychosocial predictors of CLBP disability in a rural Nigerian population.MethodsA cross-sectional study of adults with non-specific CLBP recruited from rural communities in Enugu State, South-eastern Nigeria. Measures of self-reported and performance-based disability, pain intensity, anxiety and depression, coping strategies, social support, occupational biomechanical factors, illness perceptions and fear avoidance beliefs were collected by trained community health workers. We used univariate and multivariate analyses.Results200 individuals were recruited. Psychosocial factors were the most important factors associated with CLBP disability, and accounted for 62.5% and 49.1% of the variance in self-reported and performance-based disability, respectively. The significant predictors of self-reported disability were: illness perceptions (β=0.289; p<0.0005), pain intensity (β=0.230; p<0.0005), catastrophising (β=0.210; p=0.001), fear avoidance beliefs (β=0.198; p=0.001) and anxiety (β=0.154; p=0.023). The significant predictors of performance-based disability were: illness perceptions (β=0.366; p<0.0005), social support (β=0.290; p<0.0005), fear avoidance beliefs (β=0.189; p<0.01) and female gender (β=0.184; p<0.01). Illness concern was the most salient dimension of illness perceptions predicting self-reported and performance-based disability.ConclusionsThese results provide evidence which can be used to inform the development of interventions to reduce CLBP disability in rural Nigeria, and may have relevance in other rural African contexts.
Post-traumatic growth and its relationship to quality of life up to 9 years after liver transplantation: a cross-sectional study in Spain
Authors: Pérez-San-Gregorio María Ángeles , Martín-Rodríguez Agustín , Borda-Mas Mercedes , Avargues-Navarro María Luisa , Pérez-Bernal José , Conrad Rupert , Gómez-Bravo Miguel Ángel 
Published: September 2017

ObjectiveLittle is known concerning post-traumatic growth (PTG) after liver transplantation. Against this backdrop the current study analysed the relationship between PTG and time since transplantation on quality of life. Furthermore, it compared PTG between liver transplant recipients and their caregivers.DesignCross-sectional case–control study.SettingUniversity Hospital in Spain.Participants240 adult liver transplant recipients who had undergone only one transplantation, with no severe mental disease, were the participants of the study. Specific additional analyses were conducted on the subset of 216 participants for whom caregiver data were available. Moreover, results were compared with a previously recruited general population sample.Outcome measuresAll participants completed the Posttraumatic Growth Inventory, and recipients also filled in the 12-Item Short-Form Health Survey. Relevant sociodemographic and clinical parameters were also assessed.ResultsIn the sample of 240 recipients, longer time since transplantation (>9 years) was associated with more pain symptoms (p=0.026). Regardless of duration, recipients showed lower scores on most quality of life dimensions than the general population. However, high PTG was associated with a significantly higher score on the vitality quality of life dimension (p=0.021). In recipients with high PTG, specific quality of life dimensions, such as bodily pain (p=0.307), vitality (p=0.890) and mental health (p=0.353), even equalled scores in the general population, whereas scores on general health surpassed them (p=0.006). Furthermore, liver transplant recipients (n=216) compared with their caregivers showed higher total PTG (p<0.001) and higher scores on the subscales relating to others (p<0.001), new possibilities (p<0.001) and appreciation of life (p<0.001).ConclusionsOur findings highlight the protective role of PTG in the long-term outcome of liver transplant recipients. Future studies should analyse and develop psychosocial interventions to strengthen PTG in transplant recipients and their caregivers.
Association of the Alternative Healthy Eating Index (AHEI-2010) with depression, stress and anxiety among Iranian military personnel
Authors: Rahmani Jamal , Milajerdi A , Dorosty-Motlagh A 
Published: September 2017

IntroductionPsychological disorders have a major role in the incidence of chronic diseases and may result in reductions in the cost-effectiveness of the Armed Forces. Previous civilian studies have shown a protective association between healthy eating guidelines and mental disorders, but evidence to support this for a military population is limited. The aim of this study was to examine the association of Alternative Healthy Eating Index (AHEI-2010) with depression, stress and anxiety among Iranian military personnel.MethodA cross-sectional study was conducted on 246 male Army soldiers. Stress, anxiety, depression and dietary intakes were assessed. The association between variables was determined using multivariate logistic regression.ResultsThe prevalence of depression, stress and anxiety in study participants was 15.9%, 10.6% and 27.2% respectively. Participants with the highest adherence to the AHEI-2010 had an 80% lower odds of depression than those with the lowest adherence (OR: 0.20; 95% CI 0.04 to 0.78). Such an association was also found between adherences to the AHEI-2010 and anxiety (OR: 0.28; 95% CI 0.05 to 0.95). No significant association between adherence to the AHEI-2010 and stress was found.ConclusionAn inverse association between adherence to the AHEI-2010 and odds of depression and anxiety was found. Further studies are required to clarify this relationship.
Systematic review and meta-analysis of effectiveness of preoperative embolization in surgery for metastatic spine disease
Authors: Luksanapruksa Panya , Buchowski Jacob M , Tongsai Sasima , Singhatanadgige Weerasak , Jennings Jack W 
Published: September 2017

BackgroundPreoperative embolization (PE) may decrease intraoperative blood loss (IBL) in decompressive surgery of hypervascular spinal metastases. However, no consensus has been found in other metastases and no meta-analysis which reviewed the benefit of PE in spinal metastases has been conducted.ObjectiveTo assess IBL in spinal metastases surgery in a randomized controlled trial (RCT) and cohort studies comparing PE and a control group of non-embolized patients.MethodsA systematic search of relevant publications in PubMed and EMBASE was undertaken. Inclusion criteria were RCTs and observational studies in patients with spinal metastases who underwent spine surgery and reported IBL. Meta-analysis was performed using standardized mean difference (SMD) and mean difference (MD) of IBL. Heterogeneity was assessed using the I2statistic.ResultsA total of 265 abstracts (126 from PubMed and 139 from Embase) were identified through database searching. The reviewers selected six studies for qualitative synthesis and meta-analysis. The pooled SMD of the included studies was 0.58 (95% CI −0.10 to 1.25, p=0.09). Sensitivity analysis revealed that, if the study by Rehaket alwas omitted, the pooled SMD was significantly changed to 0.88 (95% CI 0.39 to 1.36, p<0.001) and PE reduced the IBL significantly. The pooled MD was 708.3 mL (95% CI −224.4 to 1640.9 mL, p=0.14). If the results of the Rehaket alstudy were omitted, the pooled MD was significantly changed to 1226.9 mL (95% CI 345.8 to 2108.1 mL, p=0.006).ConclusionsPE can be effective in reducing IBL in spinal metastases surgery in both renal cell carcinoma and mixed primary tumor groups.
Parametric excitation of optical phonons in weakly polar narrow band gap magnetized semiconductor plasmas
Authors: Sandeep  , Dahiya Sunita , Singh Navneet 
Published: September 2017

An analytical treatment based on the hydrodynamic model of plasmas is developed to study parametric amplification and oscillation of optical phonon modes in weakly polar narrow direct-gap magnetized semiconductor plasmas. Second-order optical susceptibility arising due to nonlinear polarization and the basic operational characteristics of the parametric device, viz. threshold nature, power gain mechanisms and conversion efficiency, are obtained. The effects of doping, magnetic field and excitation intensity, on the above operational characteristics have been studied in detail. Numerical estimates are made for an n-InSb crystal at 5 K duly irradiated by a pulsed 10.6 [Formula: see text] CO2 laser. The analysis suggests the possibility of observing super-fluorescent parametric emission and oscillation in moderately doped n-InSb crystal under off-resonant nanosecond pulsed not-too-high power laser irradiation, the crystal being immersed in a large magnetic field.
Limit Order Strategic Placement with Adverse Selection Risk and the Role of Latency
Authors: Lehalle Charles-Albert , Mounjid Othmane 
Published: September 2017

This paper is split in three parts: first, we use labeled trade data to exhibit how market participants’ decisions depend on liquidity imbalance; then, we develop a stochastic control framework where agents monitor limit orders, by exploiting liquidity imbalance, to reduce adverse selection. For limit orders, we need optimal strategies essentially to find a balance between fast execution and avoiding adverse selection: if the price has chances to go down, the probability to be filled is high, but it is better to wait a little more to get a better price. In a third part, we show how the added value of exploiting liquidity imbalance is eroded by latency: being able to predict future liquidity consuming flows is of less use if you do not have enough time to cancel and reinsert your limit orders. There is thus a rationale for market makers to be as fast as possible to reduce adverse selection. Latency costs of our limit order driven strategy can be measured numerically. To authors’ knowledge, this paper is the first to make the connection between empirical evidences, a stochastic framework for limit orders including adverse selection, and the cost of latency. Our work is a first step to shed light on the role played by latency and adverse selection in optimal limit order placement.
Exploring the Recovery Lakes region and interior Dronning Maud Land, East Antarctica, with airborne gravity, magnetic and radar measurements
Authors: Forsberg Rene , Olesen Arne V. , Ferraccioli Fausto , Jordan Tom A. , Matsuoka Kenichi , Zakrajsek Andres , Ghidella Marta , Greenbaum Jamin S. 
Published: September 2017

Abstract
Long-range airborne geophysical measurements were carried out in the ICEGRAV campaigns, covering hitherto unexplored parts of interior East Antarctica and part of the Antarctic Peninsula. The airborne surveys provided a regional coverage of gravity, magnetic and ice-penetrating radar measurements for major Dronning Maud Land ice stream systems, from the grounding lines up to the Recovery Lakes drainage basin, and filled in major data voids in Antarctic data compilations, such as AntGP for gravity data, ADMAP for magnetic data and BEDMAP2 for ice thickness data and the sub-ice topography. We present the first maps of gravity, magnetic and ice thickness data and bedrock topography for the region and show examples of bedrock topography and basal reflectivity patterns. The 2013 Recovery Lakes campaign was carried out with a British Antarctic Survey Twin Otter aircraft operating from the Halley and Belgrano II stations, as well as a remote field camp located at the Recovery subglacial Lake B site. Gravity measurements were the primary driver for the survey, with two airborne gravimeters (Lacoste and Romberg and Chekan-AM) providing measurements at an accuracy level of around 2 mGal r.m.s., supplementing GOCE (Gravity Field and Steady-State Ocean Circulation Explorer) satellite data and confirming an excellent sub-milligal agreement between satellite and airborne data at longer wavelengths.
The impact of artifact correction methods of RR series on heart rate variability parameters
Authors: Rincon Soler Anderson Ivan , Silva Luiz Eduardo Virgilio , Fazan Rubens , Murta Luiz Otavio 
Published: September 2017

Heart rate variability (HRV) analysis is widely used to investigate the autonomic regulation of the cardiovascular system. HRV is often analyzed using RR time series, which can be affected by different types of artifacts. Although there are several artifact correction methods, there is no study that compares their performances in actual experimental contexts. This work aimed to evaluate the impact of different artifact correction methods on several HRV parameters. Initially, 36 ECG recordings of control rats or rats with heart failure or hypertension were analyzed to characterize artifact occurrence rates and distributions, to be mimicked in simulations. After a rigorous analysis, only 16 recordings ( n = 16) with artifact-free segments of at least 10,000 beats were selected. RR interval losses were then simulated in the artifact-free (reference) time series according to real observations. Correction methods applied to simulated series were deletion, linear interpolation, cubic spline interpolation, modified moving average window, and nonlinear predictive interpolation. Linear (time- and frequency-domain) and nonlinear HRV parameters were calculated from corrupted-corrected time series, as well as for reference series to evaluate the accuracy of each correction method. Results show that NPI provides the overall best performance. However, several correction approaches, for example the simple deletion procedure, can provide good performance in some situations, depending on the HRV parameters under consideration. NEW & NOTEWORTHY This work analyzes the performance of some correction techniques commonly applied to the missing beats problem in RR time series. From artifact-free RR series, spurious values were inserted based on actual data of experimental settings. We intend our work to be a guide to show how artifacts should be corrected to preserve as much as possible the original heart rate variability properties.
EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow–Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction
Authors: Reboll Marc R. , Korf-Klingebiel Mortimer , Klede Stefanie , Polten Felix , Brinkmann Eva , Reimann Ines , Schönfeld Hans-Joachim , Bobadilla Maria , Faix Jan , Kensah George , Gruh Ina , Klintschar Michael , Gaestel Matthias , Niessen Hans W. , Pich Andreas , Bauersachs Johann , Gogos Joseph A. , Wang Yong , Wollert Kai C. 
Published: September 2017

Background:
Clinical trials of bone marrow cell–based therapies after acute myocardial infarction (MI) have produced mostly neutral results. Treatment with specific bone marrow cell–derived secreted proteins may provide an alternative biological approach to improving tissue repair and heart function after MI. We recently performed a bioinformatic secretome analysis in bone marrow cells from patients with acute MI and discovered a poorly characterized secreted protein, EMC10 (endoplasmic reticulum membrane protein complex subunit 10), showing activity in an angiogenic screen.

Methods:

We investigated the angiogenic potential of EMC10 and its mouse homolog (Emc10) in cultured endothelial cells and infarcted heart explants. We defined the cellular sources and function of Emc10 after MI using wild-type,
Emc10
-deficient, and
Emc10
bone marrow–chimeric mice subjected to transient coronary artery ligation. Furthermore, we explored the therapeutic potential of recombinant Emc10 delivered by osmotic minipumps after MI in heart failure–prone FVB/N mice.

Results:

Emc10 signaled through small GTPases, p21-activated kinase, and the p38 mitogen-activated protein kinase (MAPK)–MAPK-activated protein kinase 2 (MK2) pathway to promote actin polymerization and endothelial cell migration. Confirming the importance of these signaling events in the context of acute MI, Emc10 stimulated endothelial cell outgrowth from infarcted mouse heart explants via p38 MAPK-MK2. Emc10 protein abundance was increased in the infarcted region of the left ventricle and in the circulation of wild-type mice after MI. Emc10 expression was also increased in left ventricular tissue samples from patients with acute MI. Bone marrow–derived monocytes and macrophages were the predominant sources of Emc10 in the infarcted murine heart.
Emc10
KO mice showed no cardiovascular phenotype at baseline. After MI, however, capillarization of the infarct border zone was impaired in KO mice, and the animals developed larger infarct scars and more pronounced left ventricular remodeling compared with wild-type mice. Transplanting KO mice with wild-type bone marrow cells rescued the angiogenic defect and ameliorated left ventricular remodeling. Treating FVB/N mice with recombinant Emc10 enhanced infarct border-zone capillarization and exerted a sustained beneficial effect on left ventricular remodeling.

Conclusions:
We have identified Emc10 as a previously unknown angiogenic growth factor that is produced by bone marrow–derived monocytes and macrophages as part of an endogenous adaptive response that can be enhanced therapeutically to repair the heart after MI.
Confucianism and Feminism in Korean Context
Authors: Kim Heisook 
Published: September 2017

AbstractThis paper considers a recent claim that Confucianism and feminism are compatible since both are care ethics. I examine some aspects of contemporary care ethics and compare them with Confucian ethics from a feminist viewpoint. I argue that for Confucianism to be made compatible with feminism, the former must be transformed to the extent that it loses its main features.Care ethics can be feminist ethics only when women have been made moral subjects because of their perceived ability to care for others. Caring in a Confucian culture is not as much a feminine value as a male value. I do not find Confucian ethics as care ethics to be particularly liberating for women. For Confucianism to be viable in a contemporary democratic world, it must be supplemented by feminist ethics that take justice and equality as the primary values.
A Guideline-Based Policy to Decrease Intensive Care Unit Admission Rates for Accidental Hypothermia
Authors: Sequeira Herman R. , Mohamed Hesham E. , Hakimi Neal , Wakefield Dorothy B. , Fine Jonathan 
Published: September 2017

Rationale: Despite guidelines advising passive rewarming for mild accidental hypothermia (AH), patients are frequently admitted to intensive care unit (ICU) for active rewarming using a forced-air warming device. We implemented a new policy at our institution aimed at safely reducing ICU admissions for AH. We analyzed our practice pre- and post-policy intervention and compared our experiences with acute care hospitals in Connecticut. Methods: A retrospective chart review was performed on 203 participants with AH identified by primary and secondary discharge codes. Our new policy recommended passive rewarming on the medical floors for mild hypothermia (>32°C) and ICU admission for moderate hypothermia (<32°C). Practices of other Connecticut hospitals were obtained by surveying ICU nurse managers and medical directors. Results: Over a 3-year period, prior to rewarming policy change, 64% (n = 92) of patients with AH were admitted to ICU, with a mean ICU length of stay (LOS [SD]) of 2.75 (2.2) days. After the policy change, over a 3-year period, 15% (n = 9) were admitted to ICU ( P < .001), with an ICU LOS of 2.11 (0.9) days ( P = 0.005). In both groups with AH, altered mental status, infection, and acute alcohol intoxication were the most common diagnoses at presentation. Alcohol intoxication was more prevalent in the post-policy intervention group, pre 17% versus post 46% ( P < .001). No complications such as dermal burns or cardiac arrhythmias were noted with forced-air warming device use during either time period. Among the 29 hospitals surveyed, 20 used active rewarming in ICU or intermediate care units and 9 cared for patients on telemetry units. Most hospitals used active external rewarming for core body temperature of <35°C; however, 37% of hospitals performed active rewarming at temperatures >35°Cor lacked a policy. Conclusions: Reserving forced-air warming devices for the treatment of moderate-to-severe hypothermia (<32°C) significantly reduced ICU admissions for AH.
Predictive Value of Matrix Metalloproteinases and Their Inhibitors for Mortality in Septic Patients: A Cohort Study
Authors: Serrano-Gomez Sergio , Burgos-Angulo Gabriel , Niño-Vargas Daniela Camila , Niño María Eugenia , Cárdenas María Eugenia , Chacón-Valenzuela Estephania , McCosham Diana Margarita , Peinado-Acevedo Juan Sebastián , Lopez M. Marcos , Cunha Fernando , Pazin-Filho Antonio , Ilarraza Ramses , Schulz Richard , Torres-Dueñas Diego 
Published: September 2017

Purpose: Over 170 biomarkers are being investigated regarding their prognostic and diagnostic accuracy in sepsis in order to find new tools to reduce morbidity and mortality. Matrix metalloproteinases (MMPs) and their inhibitors have been recently studied as promising new prognostic biomarkers in patients with sepsis. This study is aimed at determining the utility of several cutoff points of these biomarkers to predict mortality in patients with sepsis. Materials and Methods: A multicenter, prospective, analytic cohort study was performed in the metropolitan area of Bucaramanga, Colombia. A total of 289 patients with sepsis and septic shock were included. MMP-9, MMP-2, tissue inhibitor of metalloproteinase 1 (TIMP-1), TIMP-2, TIMP-1/MMP-9 ratio, and TIMP-2/MMP-2 ratio were determined in blood samples. Value ranges were correlated with mortality to estimate sensitivity, specificity, positive predictive value, negative predictive value, and area under the receiving operating characteristic curve. Results: Sensitivity ranged from 33.3% (MMP-9/TIMP-1 ratio) to 60.6% (TIMP-1) and specificity varied from 38.8% (MMP-2/TIMP-2 ratio) to 58.5% (TIMP-1). As for predictive values, positive predictive value range was from 17.5% (MMP-9/TIMP-1 ratio) to 70.4% (MMP-2/TIMP-2 ratio), whereas negative predictive values were between 23.2% (MMP-2/TIMP-2 ratio) and 80.9% (TIMP-1). Finally, area under the curve scores ranged from 0.31 (MMP-9/TIMP-1 ratio) to 0.623 (TIMP-1). Conclusion: Although TIMP-1 showed higher sensitivity, specificity, and negative predictive value, with a representative population sample, we conclude that none of the evaluated biomarkers had significant predictive value for mortality.