bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fahr disease pada pasien polineuropati diabetikum: Laporan kasus
Authors: Sunaryo Cornelius , Sunaryo Utoyo , Habibie Rizki , Andriani Nurvia 
Published: September 2024

Introduction: Fahr disease is a rare disease that affects less than one in a million people. Calcification in the basal ganglia region is the hallmark of Fahr disease. Genetic mutations or, secondarily, other systemic diseases such as hypoparathyroidism are the root cause of this condition. This case reports Fahr Disease in a patient with diabetic polyneuropathy.
Case Report: A 70-year-old male with complaints of weakness in both legs, right hand trembling, muscle weakness, and a history of uncontrolled diabetes mellitus. On neurological examination, there was a coordination system disorder. Serologic examination results showed Hba 1C levels >14%. CT scan of the brain showed bilateral symmetrical extensive calcifications in the basal ganglia in the left cerebellum.
Conclusion: Fahr Disease was discovered based on clinical findings accompanied by CT scan results showing calcification in the brain. The prognosis of this disease is undetermined, so regular evaluation is needed to assess the progression of this disease.

Pendahuluan: Fahr disease merupakan penyakit langka yang diderita pada kurang dari satu per satu juta penduduk. Kalsifikasi di daerah ganglia basalis merupakan tanda dari Fahr disease. Mutasi genetik atau sekunder oleh penyakit sistemik lain seperti hipoparatiroidisme merupakan penyebab dari penyakit ini. Pada kasus ini melaporkan tentang Fahr disease pada pasien dengan polineuropati diabetikum.
Presentasi kasus: Laki-laki berusia 70 tahun dengan keluhan lemah pada kedua kaki, tangan kanan gemetar, kelemahan otot, dan riwayat diabetes melitus yang tidak terkontrol. Pada pemeriksaan neurologi terdapat gangguan sistem koordinasi. Hasil pemeriksaan serologi didapatkan kadar Hba1c >14%. CT scan otak menunjukkan kalsifikasi luas simetris bilateral pada basal ganglia di serebelum kiri.
Kesimpulan: Fahr disease ditemukan berdasarkan temuan klinis disertai dengan hasil CT scan yang menunjukkan adanya kalsifikasi pada otak. Prognosis penyakit ini belum dapat ditentukan, sehingga perlu dilakukan evaluasi secara berkala untuk menilai perkembangan penyakit ini.
Tatalaksana Terkini Skar Atrofi: Sebuah Tinjauan Literatur
Authors: Darmaputra I Gusti Nyoman 
Published: September 2024

Scars are the culmination of the natural healing and reparative process resulting from the formation of dermal fibrotic scars following inflammation. Atrophic scars are widely characterized by generalized skin atrophy resulting in the loss of skin cells in the epidermis, clinically appearing as the loss of normal dermis. Atrophic scars occur more frequently than hypertrophic and keloid scars, with a ratio of 3:1.9. Atrophic scars present a significant challenge for reconstructive specialists, thus becoming a topic worthy of continuous study based on the latest consensus. The management of atrophic scars is differentiated based on the type of scar. Atrophic acne vulgaris scars can be treated with Resurfacing and Tightening techniques, Dermal Lift, dermal volumization, or combination therapy. Striae alba atrophic scars can be addressed using a combination of jet volumetric remodeling (JVR) with fractional laser. Burn atrophic scars can be treated using ablative and non-ablative laser techniques. Atrophic scars can be prevented by assessing risk, optimal wound care, and selecting surgical techniques appropriate for the type of scar.

Skar adalah hasil akhir dari proses penyembuhan dan reparatif alami sebagai akibat dari pembentukan skar fibrotik dermal pasca peradangan. Skar atrofi secara luas digambarkan dengan adanya atrofi kulit umum yang mengakibatkan hilangnya sel-sel kulit di epidermis yang secara klinis tampak sebagai hilangnya dermis normal. Skar atrofi lebih sering terjadi dibanding skar hipertrofi dan keloid, dengan rasio 3:1.9. Skar atrofi menghadirkan tantangan yang signifikan bagi spesialis rekonstruksi, sehingga menjadi topik yang patut dipertimbangkan untuk terus dikaji secara kontinyu berdasarkan konsensus terbaru. Tatalaksana skar atrofi dibedakan berdasarkan jenis skar. Skar atrofi akne vulgaris dapat diberikan terapi dengan teknik Resurfacing and Tightening, Dermal Lift, volumisasi dermal maupun terapi kombinasi. Skar atrofi striae alba dapat menggunakan kombinasi jet volumetric remodeling (JVR) dengan laser fraksional. Skar atrofi luka bakar dapat menggunakan teknik laser ablatif dan non-ablatif. Skar atrofi dapat dicegah dengan menilai risiko, perawatan luka yang optimal dan pemilihan teknik pembedahan yang sesuai dengan jenis skar.
Reaksi erupsi obat eksantematosa karena ciprofloxacin
Authors: Wahyuni Anak Agung Candra , Pradnyandari Ida Ayu Cintya , Pemayun Tjokorda Dalem 
Published: September 2024

Background: Exanthematous drug eruption is a skin disease induced by drugs and mediated by a type IV hypersensitivity reaction. The characteristic features are erythema macules and multiple morbilliform papules that spread rapidly, widely, and confluently.
Case illustration: A 32 year old woman came to the Emergency Unit Wangaya Regional General Hospital with complaints of reddish spots on her face, neck, chest, stomach, arms, and legs since 5 days before entering the hospital. Complaints accompanied by itching all over the body. The patient has a history of taking the antibiotic ciprofloxacin 3 days ago. In the facial region, anterior thoracic region, abdominal region, antebrachia region, dorsum pedis region, there are multiple erythema macules and papules with generalized and confluent distribution.
Conclusion: The diagnosis of extanthematous drug eruption is made based on the history and physical examination. The main treatment is identifying and stopping the use of the causative drug. Another therapy is pharmacological therapy which is symptomatic. In this case, the patient is given systemic corticosteroids, antihistamine therapy, topical corticosteroids, and antibiotics.

Latar Belakang: Erupsi obat eksantematosa adalah salah satu penyakit pada kulit yang diinduksi oleh obat dan dimediasi oleh reaksi hipersensitivitas tipe IV. Gambaran karakteristik yang khas berupa makula eritema dan papul multipel morbiliformis, menyebar dengan cepat dan luas serta konfluens.
Ilustrasi kasus: Seorang wanita berusia 32 tahun datang ke Unit Gawat Darurat, Rumah Sakit Umum Daerah (RSUD) Wangaya dengan keluhan bintik-bintik kemerahan pada wajah, leher, dada, perut, lengan dan kaki sejak 5 hari sebelum masuk rumah sakit. Keluhan disertai rasa gatal di seluruh tubuh. Pasien memiliki riwayat mengonsumsi antibiotik ciprofloxacin 3 hari yang lalu. Pada regio facialis, regio thorakalis anterior, regio abdomen, regio antebrachia, regio dorsum pedis terdapat macula dan papul eritema multipel dengan distribusi generalisata dan konfluens.
Simpulan: Diagnosis erupsi obat ekstantematosa ditegakkan berdasarkan anamnesis dan pemeriksaan fisik. Penatalaksanaan utama adalah mengidentifikasi dan menghentikan penggunaan obat pennyebab. Terapi lainnya adalah terapi farmakologi yang bersifat simptomatik. Dalam kasus ini pasien diberikan terapi kortikosteroid dan antihistamin sistemik, serta kortikosteroid dan antibiotik topikal.
Riwayat adiksi internet pada anak dengan skizofrenia: laporan kasus
Authors: Kartika Dewa Ayu Bintang , Basudewa I Dewa Gede 
Published: September 2024

Background: Internet addiction is excessive use of the internet by individuals. Internet addiction is characterized by several symptoms in the form of compulsive symptoms, withdrawal symptoms and tolerance symptoms. There are few reported cases of internet addiction in children, especially children with special needs or mental disorders such as schizophrenia.
Case Description: A 14 year old boy came to the Bali Provincial Mental Hospital with complaints of rage and was diagnosed with schizophrenia. During the treatment period, it was discovered that one of the factors that caused the patient to go berserk was that he was not given a gadget to play on the internet. The patient's mood during the initial period of treatment appeared irritable. The patient was given therapy with Quetiapine 2x200mg, Depakote 3x250mg, and Haloperidol 2x2.5mg.
Conclusion: After carrying out an examination using the Internet Addiction Diagnostic Questionnaire, the result was 167, namely Internet Addiction and the results of the Internet Addiction Test (IAT) were moderate Internet addiction.

Latar Belakang: Kecanduan internet adalah penggunaan internet yang dipakai berlebihan oleh individu. Kecanduan internet ditandai oleh beberapa gejala berupa compulsive symptom, withdrawal symptom dan Tolerance symptoms. Sedikit kasus yang dilaporkan mengani adiksi internet pada anak terutama pada anak berkebutuhan khusus atau dengan gangguan mental seperti skizofrenia.
Deskripsi Kasus: Anak laki-laki, 14 tahun datang ke Rumah Sakit Jiwa Provinsi Bali dengan keluhan mengamuk dan didiagnosa dengan Skizofrenia. Dalam masa perawatan didapatkan salah satu faktor yang membuat pasien mengamuk adalah tidak diberikan gadget untuk bermain internet. Mood pasien selama masa awal perawatan tampak irritable. Pasien diberikan terapi dengan Quetiapine 2x200mg, Depakote 3x250mg, dan Haloperidol 2x2,5mg.
Simpulan: Setelah dilakukan pemeriksaan menggunakan Kuisioner Diagnostik Adiksi Internet didapatkan hasil 167 yaitu Kecanduan Internet dan hasil Internet Addiction Test (IAT) adalah kecanduan internet sedang.
Effect of the brass waste recycling process on mechanical properties with investment casting for gear materials
Authors: Erwin Erwin , Sugiyanto Didik , Faturahman Danny , Chan Yefri , Asbanu Husen 
Published: September 2024

This study is an experimental research to analyze the characteristics and mechanical properties of the casting process of recycled brass alloy, which will be used as a material for gears. Currently, the remaining production and waste from brass alloys continue to increase. Another thing is the increase in the need for brass gears, so environmentally friendly material engineering is needed to provide good quality and efficient energy use, especially during the casting process. The casting process uses an electric furnace that melts brass alloys at 526 up to 900 °C within 1 hour and molds to make test specimens. The results of microstructural testing for grain size in recycled brass alloys range from 74.63 μm to 84.57 μm. The maximum tensile strength produced is up to 225.2 MPa, the maximum yield strength is up to 179.8 MPa, and the maximum elongation is up to 7.3 %. The roughness of recycled brass alloys has a maximum Ra value (average roughness) of up to 0.836 μm. Validation was carried out by comparing the mechanical properties of CAC 302 brass products and the study results. The data shows that recycled brass's maximum yield strength value is 179.8 MPa and CAC 302 brass material is 175 MPa, but for the ultimate tensile strength value, the value of recycled brass is far below CAC 302 products. These results can be a consideration for the industry to be able to use recycled brass alloys for gear products because the yield strength value is not far from CAC 302 brass products. The impact result of this study produces recycled brass alloys that are environmentally friendly, efficient in smelting energy consumption, and have good yield strength. The results of this research can benefit the manufacture of gear components made of brass alloys.
Comparison of the hardness value and microstructure of Al6061 in horizontal centrifugal casting with and without mold cooling
Authors: Suprapto Agus , Tsamroh Dewi Izzatus , Andrijono Djoko , Maswain Septian Dwi Irianto 
Published: September 2024

The object of this research is the horizontal centrifugal casting process of the Al6061 alloy. Usually, cast products experience some casting defects, so the horizontal centrifugal casting process is applied to reduce the possibility of casting defects arising. In some casting processes, especially in the production of cylindrical specimens, casting defects such as porosity are encountered. Therefore, horizontal centrifugal casting was applied to overcome this problem. The test results show that the average hardness value for aluminum 6061 specimens resulting from centrifugal casting products with water cooling was 73.3 HRE, while the average hardness value for aluminum 6061 specimens resulting from centrifugal casting products without water cooling was 86.4 HRE. The microstructure results show that the grain size of centrifugal casting products with water cooling was 82.5 µm, whereas without water cooling it was 75 µm. Higher hardness values were obtained in specimens without mold cooling, this is because the conductivity in molds without cooling was higher compared to molds that experienced water cooling. The higher the heat conductivity of the mold, the faster the cooling process of the cast product. The casting process using the horizontal centrifugal method can be carried out to produce cylindrical spare parts
Assessing the efficiency of the effect of innovations on the development of grain processing enterprises
Authors: Yessakhmetova Lyailya , Dzholdasbaeva Gulnar , Saurukova Ainura , Sauranova Meruert , Alibekova Aigul 
Published: September 2024

This study evaluates the impact of the introduction of deep grain processing on the development of grain processing enterprises. The main problems of processing grain crops in the Republic of Kazakhstan have been considered. The need to assess the impact of the innovative process of enterprise development was outlined. The research was carried out in the North-Kazakhstan region; the object of the study was the grain processing industries in the North-Kazakhstan region.
The results show the following:
1) total cost savings when expanding the level of gluten consumption (up to 3 % by weight of the volume of flour consumed) will save USD 18.5 billion. The savings are due to the significant improvement in the baking properties of the flour when adding 1−3 % gluten to the level of the highest quality wheat flour. At the same time, due to the manufacturability of the process and the use of the lowest quality raw materials, the unit cost of gluten in terms of protein is lower than the price of high-quality wheat necessary for baking;
2) in the processing of starch and amino acids, grain starch is the main product of world trade among all goods of the grain processing industry, and gluten ranks only second in terms of world imports. The share of issued patents in the area of starch production is also leading among the sectors of deep grain processing;
3) the implementation of the developed project for deep processing of grain in Northern Kazakhstan could significantly improve the indicators of innovative development of the country: the increase in innovative products of the manufacturing industry in the country as a whole would be 19.1 %. The growth of non-resource exports would equal 1.5 %. The annual increase in the enterprise's revenue could be about USD 0.47 per USD 1 of investment costs compared to the base scenario for the sale of unprocessed wheat.
The scope of practical application of the results extends to the grain industry. The project has a significantly wider range of manufactured products and is focused on the markets of neighboring countries, which could reduce export risks to a minimum and provide stable demand for the company’s products
Determining patterns of the vertical load on a covered wagon roof with a frame in the form of a triangular arch
Authors: Lovska Alyona , Stanovska Iraida , Prokopovych Ihor , Sydorenko Ihor , Muradian Arsen 
Published: September 2024

The object of this paper is the processes of perception and redistribution of loads in the roof of a railroad covered wagon with a frame in the form of a triangular arch.
To reduce the tare of the covered wagon, it is proposed to improve the structure of its roof. A feature of this improvement is that the roof frame is made in the form of a triangular arch with a reinforcing belt. This contributes to the reduction of the total mass of the roof compared to a typical structure. The selection of execution profiles of the beams forming the arch is carried out according to the maximum values of the moments that act in their cross-section. Taking into account the chosen profile of the arches, the calculation of the strength of the roof when it receives vertical loads was carried out. It was established that the strength of the roof under the considered load schemes is within the permissible stress values. Since the improvement of the roof structure contributes to the reduction of its weight by 1.8 % compared to the prototype, the movement of the covered wagon was evaluated under conditions of moving while empty. To this end, a mathematical modeling of the load of the covered wagon in the vertical plane during its movement along the joint unevenness was carried out. On the basis of the performed calculation, it was established that the movement of the wagon is assessed as "good".
Special feature of the results is that the reduction of the tare of the supporting structure of the wagon was achieved by improving its roof, as the least loaded unit.
The field of practical application of the results is railroad transport, including other areas of mechanical engineering. The conditions for the practical use of the results are a symmetrical roof load scheme in operation.
The results of this research could contribute to advancements related to the design of modern structures of freight wagons with improved technical and economic indicators
Development of binders based on the СаО–Fe2O3 system
Authors: Derevianko Victor , Hryshko Hanna , Smolin Denis , Zhurba Ivan , Dubov Taras 
Published: September 2024

The object of research is the processes of structure formation and modeling of the properties of a specialized binder. The development of new binding materials based on production waste with high early strength indicators could make it possible to speed up construction period and is one of the urgent tasks at present. This study focused on the creation of binders based on the СаО–Fe2O3 system. The developed binder of the СаО–Fe2O3 system has the following composition: limestone – 26 %; red slime – 74 %, which has a dense fine-porous structure and high early strength indicators – 22.5 MPa with a density of 1960 kg/m3. There is also an increase in the average density of samples annealed at a temperature of 1200 ℃ for 60 minutes, ground and mixed with water, in comparison with samples fired at 1100 ℃ for 60 minutes, by 500 kg/m3, due to new formations. The prospect of using modified composite binders with special functional properties has been substantiated. The use of production waste based on the СаО-Fe2O3 system could make it possible to obtain materials with high physical and mechanical properties, which makes them promising for application in various areas of the construction industry. The development of such binders will help reduce the environmental impact of the construction industry, owing to the use of affordable and effective components. This approach will not only contribute to the improvement of the quality of building materials but also help reduce the ecological burden on the environment by using alternative resources and industrial waste. The developed binder could be used for the development of solutions for 3d printing, as well as repair of concrete coatings
Effect of box beam wall thickness on the stiffness of the camphor wood timber bridge truss
Authors: Wijaya Handika Setya , Oktaviastuti Blima , Damayanti Fifi , Ariningsih Yeni Sesti 
Published: September 2024

Bridges are vital for community development, and wood is a primary material due to its environmental benefits. However, wood’s moisture absorption can cause swelling and shrinkage, and low-density wood tends to have lower strength. The moment of inertia of a box beam is related to wall thickness and stiffness. Insufficient wall thickness can lead to plastic retention before peak load, reducing structural integrity. Thin walls can cause buckling under compressive loads, leading to failure. Truss bridge failures can also result from design errors. This study aims to analyze the effect of box beam wall thickness on the stiffness of camphor wood timber bridge trusses. Camphor wood with a cross-sectional area of 1,600 mm2 was used, with box beams of dimensions 45×45 mm (12 mm wall), 50×50 mm (10 mm wall), 58×58 mm (8 mm wall), and a solid beam of 40×40 mm (20 mm wall). Physical tests showed the wood’s specific gravity at 0.506 g/cm3 and moisture content at 12.47 %. The highest peak load was 19.613 kN for the BB.58.58.8 variation, which also had the greatest stiffness at 3.502 kN/mm. The BB.58.58.5 variation had the largest moment of inertia at 683,733 mm4 compared to the solid beam SB.40.40.20 at 213,333 mm4. The BB.45.45.12 sample had a t/D ratio 1.93 times larger than BB.58.58.8, indicating a more flexible structure with lower stiffness. This is confirmed by experimental results, showing that BB.45.45.12 had a stiffness 1.73 times lower than BB.58.58.8. Theoretical calculations also showed that BB.45.45.12 had a stiffness 2.03 times smaller than BB.58.58.8. Thus, the t/D ratio is inversely proportional to stiffness. This research contributes valuable insights for developing engineered wood products in construction and bridge design, particularly for village bridges in Indonesia
Determining of the effect of reinforcing microrelief guides on the efficiency of folding integrated covers
Authors: Kyrychok Petro , Paliukh Dmytro 
Published: September 2024

The object of research is the processes of strengthening the working surfaces of profile folding strips made of stainless steel AISI 347 and carbon steel AISI 1005 using laser formation of microrelief guides. The analytical and experimental studies are based on the technique of laser microrelief formation by pulsed laser effects. The main assumption of the study is that the use of laser microrelief formation could increase the hardness and wear resistance of the folding strips, improving the process of folding integrated covers. Analyzing the effect of different hardening methods on the mechanical properties and wear resistance of the working surfaces of folding strips is necessary to achieve this goal. A methodology for assessing microstructural changes and their impact on the mechanical properties of folding strips during laser hardening has been proposed. It has been shown that the formation of microrelief guides by laser pulse exposure reduces the thermal load on the material, increases the uniformity of hardening and wear resistance. The revealed wear rates calculated for carbon steel AISI 1005 are 0.875, and for stainless steel AISI 347 – 0.345. To improve the accuracy and efficiency of the folding process, a methodology has been devised for calculating the quantitative formation of microrelief guides on the working surface of profile folding strips. This will not only improve the wear resistance and mechanical properties of the strips but also optimize production processes. Differences in the results of hardening for stainless steel AISI 347 and carbon steel AISI 1005 were found: the hardness values for AISI 347 are 3,088–4,904 MPa at a load of 50–350 g with a deviation of 37.1 %, and for AISI 1005 – 2141–1665 MPa with a deviation of 22.3 %