bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catharsis – Philosophical and Spiritual Aspects of Long-Distance Running
Authors: Nemec Marcel 
Published: May 2016

Summary
The purpose of the study was to identify and analyze the occurrence of cathartic states in a sample of long-distance runners. Data collected via questionnaires were used to evaluate quantitative variables complemented by heuristics while aiming at qualitatively categorize the areas of cathartic states in the context of philosophical and spiritual aspects of long-distance running. The study findings objectify philosophical and spiritual aspects affecting personalities of long-distance runners. The study findings have shown that catharsis represents a relevant philosophical and spiritual aspect affecting long-distance running. We assume that authentic experience of catharsis and its effects motivates runners to perform regular physical activity. The analysis of philosophical and spiritual aspects of long-distance running has revealed a multi-spectral holistic relevance based on the transfer affecting a specific way of life, spectrum of values, ethical personality traits, and also the quality of long-distance runners’ lives.
Determination of Static Characteristics of Flow Flotation Machines Based on Experiments of the Kinetics of the Batch Coal Flotation
Authors: Kalinowski Krystian , Kaula Roman 
Published: May 2016

Abstract
In the theory and a simulation technique of a coal flotation process a density function of a distribution of particles flotability is widely used. The characteristics of this type in the design of the flotation circuits as well as to optimize of the settings of the industrial flotation machines may be used. The density function of the distribution of the fraction f (k) based on the kinetics experiments to measure the recovery of material as a function of time in the laboratory flotation machines (in the batch coal flotation process) is determined. The problems of the determining of the flotability spectrum are relatively well resolved. An important problem is the determination of the concentrate quality. The concentrate quality directly depends on the ash content in the concentrate. In the paper a mathematical model of the separation of the mass of ash at the process of the kinetics of the batch flotation has been proposed. The research at different values of the air flow rate was carried out. The results of the analyses in tables and graphs are shown. The static characteristics of the single-cell of the flow flotation machine based on the characteristics of the distribution density of the fraction f (k) and the distribution of the ash content ak(k) were determined. Knowledge of these relationships will allow for a better assessment of the phenomena occurring in the enrichment process. This may be one of the basic information used in the supervisory control system of the flotation process.
Factors Creating Economic Value Added of Mining Company
Authors: Bluszcz Anna , Kijewska Anna 
Published: May 2016

Abstract
The company’s strategy that focuses on the growth of the company represented by the economic value added (EVA) requires the identification of factors affecting the size of the EVA. For this purpose, in the paper the formula for EVA was transformed in such a way as to reveal the determinants affecting its value. Three levels of disaggregation of EVA were assumed. At the first level EVA depends on the amount of invested capital (IC) and economic spread (EC). At the second level economic spread is expressed using the weighted average cost of capital (WACC) and the return on invested capital (ROIC). The third level takes into account the capital structure (wi), the cost of capital (ki), the profit margin (NOPAT/S) and invested capital turnover ratio (S/IC). Such disaggregation can be continued on the next levels of detail.
Using the method of successive substitutions an analysis of the cause and effect of the mining company, was conducted. In this way, we can indicate which factors and to what extent affected negatively and positively the change of EVA in the analysed year compared to the previous year. Such analysis allows decision makers to determine a strategy directed to the increase of the mining company’s value.
Influence of the A2 motorway on the economic development at local level
Authors: Bogdański Marcin 
Published: May 2016

Abstract
The aim of the paper is to analyze the selected investment in transport infrastructure in terms of its impact on the economy at the local level. The study involves ten gminas within a 60 km radius (approximately 1 hour’s traveling distance) of Poznań. Using the available statistical data set, it was determined whether the construction of the motorway had an impact on the number and the structure of enterprises located in the surveyed communities, the levels of gmina revenues, and the situation on the labour market.
Performed analysis allowed reaching a positive verification of the research hypothesis, which predicts that the A2 did not have a decisive impact on the economic development of the gminas. In all of the included aspects, gminas located along the A2 were characterized by a relatively high level of economic development compared to the Wielkopolskie Voivodship and the rest of Poland. At the same time, the level of development was lower when compared with gminas within the Poznań Poviat. These results suggest that the decisive factor in shaping the level of economic development was their geographic location in relation to the nearby urban agglomeration of Poznań.
Forest fires in Dalmatia
Authors: Šiljković Željka , Mamut Marica 
Published: May 2016

Abstract
Every year the Republic of Croatia, especially in its south part in Dalmatia, faces forest fire risks. The weather is exceptionally conducive to fires, so the main period of fire occurrences is between June and October, characterized by long lasting dry and warm weather with temperatures over 30°C. Research carried out by the authors in 1997 and 2012 have pointed to the fact that human impact is the main cause of ignition. This paper presents an overview of the total number of fires in the period from 1998 to 2012, with the emphasis on forest and woodland fires in the Croatian region of Dalmatia. Data on the situation in Dalmatia refer to the situation in the areas of responsibility of four Dalmatian Police Administrations. Analysis is based on official data of the Croatian Ministry of the Interior and the report of the National councillor for managing and controlling forest fires. The authors have analysed the frequency of forest fires in Dalmatia in a period of fourteen years (1998-2012) comparing it with the previous period, 1989-1996. The results that the authors have obtained reveal how forest fires most commonly (2/3) break out during the warm part of a day, from 09.00 until 18.00 hours in the warm period of the year. Particularly vulnerable are the forests of Aleppo pines and maquis being mostly thermal forests, whilst in the south of the country the forests of Holm oak (Quercus ilex) and English oak (Quercus robur) are at the highest risk. Reforesting of burned areas is very slow and Croatia has been far behind in reforesting in the continental part of the country.
Food as the Representation of Idyllic Landscape of Victorian World in the Novels by Thomas Hardy
Authors: Buda Agata 
Published: May 2016

Abstract
The aim of the paper is to analyse the idea of cooking/eating in two novels by Thomas Hardy: Jude the Obscure and Tess d’Urbervilles. Both works present the idea of food as one of the major points of reference in human relationships. One of the aspects worth analysing is eating as one of the most crucial primary needs. Another one is family eating. The meetings are preceded by careful preparation of meals (e.g. Sunday preparations in Arabella’s house or cooking in the house of the Crick family). The food often becomes the major topic during these meetings, showing in this way the idyllic character of family eating: the looks of dining rooms and kitchens are essential as well as the possibility of talking to each other while eating. This idyllic space of collective eating (according to M. Bakhtin) can be frequently destroyed by social conventions; when Tess was rejected by society, she used to eat alone and did not take care of what she eats. Both novels explore the idea of food making it important for the creation of an idyll.
Role of interlekin-35 as a biomarker in patients with newly diagnosed Hashimoto’s thyroiditis
Authors: Yilmaz Hakki , Cakmak M. , Ceydilek B. , Demir C. , Aktas A. 
Published: May 2016

Abstract
Objective. Interleukin-35 (IL-35), an interleukin-12 (IL-12) cytokine family member, is shown to be a potent immunosuppressive and anti-inflammatory cytokine. Inducible regulatory T cells (Tregs) produce IL-35 that mediates the immune inhibitory function of Tregs. Growing evidence revealed that upregulation of IL-35 expression may play a critical role in the prevention of autoimmune diseases in various experimental autoimmunity models and vice versa. Hashimoto’s thyroiditis (HT) is considered to be a Treg cell-related autoimmune disease with loss of self-tolerance.
Methods. One hundred-twenty eight subjects, newly diagnosed hypothyroid HT patients [56 overt (Group 1), 72 subclinical hypothyroid (Group 2)] and 38 healthy controls (Group 3) were enrolled in the study. The levels of serum IL-35 were determined by enzyme-linked immunosorbent assay (ELISA).
Results. Serum IL-35 levels were lower in the HT group when compared with subclinical HT group [304.5 (834.6) pg/ml vs. 636.1 (1542.0) pg/ml, p=0.004] and control cases [304.5 (834.6) pg/ml vs. 1064.7 (2526.8) pg/ml, p<0.001]. Serum IL-35 levels were inversely associated with thyroid stimulating hormone (TSH; rs=-0.396, p<0.001) and anti-thyroid peroxidase antibodies (TPOAb; rs=-0.571, p<0.001) in whole group. Serum IL-35 were negatively associated with TSH (rs=-0.264, p=0.003) and TPOAb (rs=-0.735, p<0.001) in patients with Hashimoto’s thyroiditis (Group 1 + Group 2).
Conclusion. The results suggest that IL-35 may play a role in the pathogenesis of HT.
Progress in micro RNA focused research in endocrinology
Authors: Voglova K. , Bezakova J. , Herichova Iveta 
Published: May 2016

Abstract
Micro RNAs (miRNAs) are small regulatory molecules of increasing biologists’ interest. miRNAs, unlikely mRNA, do not encode proteins. It is a class of small double stranded RNA molecules that via their seed sequence interact with mRNA and inhibit its expression. It has been estimated that 30% of human gene expression is regulated by miRNAs. One miRNA usually targets several mRNAs and one mRNA can be regulated by several miRNAs. miRNA biogenesis is realized by key enzymes, Drosha and Dicer. miRNA/mRNA interaction depends on binding to RNA-induced silencing complex. Today, complete commercially available methodical proposals for miRNA investigation are available. There are techniques allowing the identification of new miRNAs and new miRNA targets, validation of predicted targets, measurement of miRNAs and their precursor levels, and validation of physiological role of miRNAs under in vitro and in vivo conditions. miRNAs have been shown to influence gene expression in several endocrine glands, including pancreas, ovary, testes, hypothalamus, and pituitary.
Personalized Information Management by Online Stores in 4C Model. Case Study
Authors: Kubicka Anna 
Published: May 2016

AbstractThe increasing complexity of the business environment, growing knowledge requirements, development of information technologies, and competitiveness implies the need of implementation of information management systems. Moreover, welter of information about online customers, their individual behavior, and their expectations force entrepreneurs to manage information in a personalized way. Monitoring Internet users behavior, creating their profiles (based on data about age, sex, lifestyle, interests, family, work, etc.), and controlling current traffic on the Web site give wide range of possibilities in creating a real model of potential customers preference and using it in online communication. This study concentrates on possibilities of using personalized communication in the information management by online stores in 4C model.
The Perceptions of Management on the Benefits of Adopting an Environmental Management Accounting System as a Waste Management Tool
Authors: Doorasamy Mishelle 
Published: May 2016

AbstractThe purpose of this paper is to ascertain the perception of management on the benefits of adopting an environmental management accounting (EMA) system as a waste management tool in a paper and pulp manufacturing company. This paper highlights the benefits of an EMA system and the role and importance of EMA as a decision-making tool in encouraging the adoption of cleaner production (CP) techniques and technologies. This research was based on a case study of a paper and pulp manufacturing company in KwaZulu-Natal. This research was both quantitative and qualitative in nature. Data collection instruments for the study included a Likert-type questionnaire and interviews with the environmental manager and cost accountant but the findings reported in this paper are based on the empirical evidence gathered from the questionnaire which identified that there was positive correlation between environmental performance and CP techniques and technologies. Environmental costs were hidden under general overheads and understated because the company was using a conventional costing system and not an EMA system; hence, environmental costs were not traced back to the products or processes responsible for those costs. It was evident from the qualitative data analysis that management regarded their environmental costs as too insignificant to justify implementation of an EMA system. The consequent reluctance of the company to adopt CP resulted in poor waste management and lower-quality environmental performance.
Parkinsonian Syndrome and Toxoplasmic Encephalitis
Authors: Arbune Anca-Adriana , Arbune Manuela , Stefanescu Victorita 
Published: May 2016

Abstract
Toxoplasmosis encephalitis in patients with human immunodeficiency virus may progress rapidly with a potentially fatal outcome. Less common neurological symptoms associated with this are Parkinsonism, focal dystonia, rubral tremor and hemichorea–hemiballismus syndrome.
A 58 year old woman suddenly lost consciousness and was admitted to the emergency service. Her medical history was unremarkable, except for frequent headaches in the last year, recurrent herpes simplex skin lesions and an episode of urticaria. A computer tomography scan showed supra and infra-tentorial lesions on suggestive of cerebral toxoplasmosis. Both Toxoplasma gondii and HIV tests were positive. In the intensive care unit, antiparasitic and antiretroviral drugs were administered, and she recovered from the coma after six weeks but presented with tetraparesis, diplopia, and depression. The LCD4 count increased from 7 to 128/mm3. The neurological lesions slowly resolved over the next two months, although postural instability, rigidity, bradykinesia and predominantly left side tremor persisted. Mild improvement was achieved after the administration of levodopa.
Associated Parkinsonian syndrome in HIV patients is a rare condition, explained by the location of the brain and basal ganglia lesions, and by the observed effect of Toxoplasma gondii which increases dopamine metabolism in neural cells. Early HIV diagnostic and treatment are necessary to prevent neurological disability.
Comparison of Olympic and Hexagonal Barbells With Midthigh Pull, Deadlift, and Countermovement Jump
Authors: Malyszek Kylie K. , Harmon RoQue A. , Dunnick Dustin D. , Costa Pablo B. , Coburn Jared W. , Brown Lee E. 
Published: May 2016

Abstract
Malyszek, KK, Harmon, RA, Dunnick, DD, Costa, PB, Coburn, JW, and Brown, LE. Comparison of olympic and hexagonal barbells with midthigh pull, deadlift, and countermovement jump. J Strength Cond Res 31(1): 140–145, 2017—Those training for strength and power commonly use different bars and different lifts. The hexagonal barbell (HBar) and Olympic barbell (OBar) are frequently used training implements, and the midthigh pull (MTP) and deadlift (DL) are 2 popular exercises. Therefore, the purpose of this study was to compare force between an HBar and OBar for a MTP, DL, and countermovement jump (CMJ). Twenty resistance-trained men (age = 24.05 ± 2.09 years, ht = 178.07 ± 7.05 cm, mass = 91.42 ± 14.44 kg) volunteered to participate and performed MTP and DL using both bars and a CMJ. Joint angles were recorded for all pulls and the bottom position of the CMJ. Peak ground reaction force (PGRF) was greater in the MTP (3,186.88 ± 543.53 N) than DL (2,501.15 ± 404.04 N) but not different between bars. Midthigh pull joint angles were more extended than DL, and the strongest correlations between isometric and dynamic performance were seen between DL PGRF and CMJ impulse (OBar r = 0.85; HBar r = 0.84). These findings are likely because of the different anatomical characteristics between the MTP and DL and the similarity in joint angles between the DL and CMJ. Therefore, the DL may be an optimal choice for athletes in jump-dependent sports, regardless of bar.
Pallidostriatal Projections Promote β Oscillations in a Dopamine-Depleted Biophysical Network Model
Authors: Corbit Victoria L. , Whalen Timothy C. , Zitelli Kevin T. , Crilly Stephanie Y. , Rubin Jonathan E. , Gittis Aryn H. 
Published: May 2016

In the basal ganglia, focused rhythmicity is an important feature of network activity at certain stages of motor processing. In disease, however, the basal ganglia develop amplified rhythmicity. Here, we demonstrate how the cellular architecture and network dynamics of an inhibitory loop in the basal ganglia yield exaggerated synchrony and locking to β oscillations, specifically in the dopamine-depleted state. A key component of this loop is the pallidostriatal pathway, a well-characterized anatomical projection whose function has long remained obscure. We present a synaptic characterization of this pathway in mice and incorporate these data into a computational model that we use to investigate its influence over striatal activity under simulated healthy and dopamine-depleted conditions. Our model predicts that the pallidostriatal pathway influences striatal output preferentially during periods of synchronized activity within GPe. We show that, under dopamine-depleted conditions, this effect becomes a key component of a positive feedback loop between the GPe and striatum that promotes synchronization and rhythmicity. Our results generate novel predictions about the role of the pallidostriatal pathway in shaping basal ganglia activity in health and disease.SIGNIFICANCE STATEMENTThis work demonstrates that functional connections from the globus pallidus externa (GPe) to striatum are substantially stronger onto fast-spiking interneurons (FSIs) than onto medium spiny neurons. Our circuit model suggests that when GPe spikes are synchronous, this pallidostriatal pathway causes synchronous FSI activity pauses, which allow a transient window of disinhibition for medium spiny neurons. In simulated dopamine-depletion, this GPe-FSI activity is necessary for the emergence of strong synchronization and the amplification and propagation of β oscillations, which are a hallmark of parkinsonian circuit dysfunction. These results suggest that GPe may play a central role in propagating abnormal circuit activity to striatum, which in turn projects to downstream basal ganglia structures. These findings warrant further exploration of GPe as a target for interventions for Parkinson's disease.
Npas1+Pallidal Neurons Target Striatal Projection Neurons
Authors: Glajch Kelly E. , Kelver Daniel A. , Hegeman Daniel J. , Cui Qiaoling , Xenias Harry S. , Augustine Elizabeth C. , Hernández Vivian M. , Verma Neha , Huang Tina Y. , Luo Minmin , Justice Nicholas J. , Chan C. Savio 
Published: May 2016

Compelling evidence demonstrates that the external globus pallidus (GPe) plays a key role in processing sensorimotor information. An anatomical projection from the GPe to the dorsal striatum has been described for decades. However, the cellular target and functional impact of this projection remain unknown. Using cell-specific transgenic mice, modern monosynaptic tracing techniques, and optogenetics-based mapping, we discovered that GPe neurons provide inhibitory inputs to direct and indirect pathway striatal projection neurons (SPNs). Our results indicate that the GPe input to SPNs arises primarily from Npas1-expressing neurons and is strengthened in a chronic Parkinson's disease (PD) model. Alterations of the GPe-SPN input in a PD model argue for the critical position of this connection in regulating basal ganglia motor output and PD symptomatology. Finally, chemogenetic activation of Npas1-expressing GPe neurons suppresses motor output, arguing that strengthening of the GPe-SPN connection is maladaptive and may underlie the hypokinetic symptoms in PD.SIGNIFICANCE STATEMENTAn anatomical projection from the pallidum to the striatum has been described for decades, but little is known about its connectivity pattern. The authors dissect the presynaptic and postsynaptic neurons involved in this projection, and show its cell-specific remodeling and strengthening in parkinsonian mice. Chemogenetic activation of Npas1+pallidal neurons that give rise to the principal pallidostriatal projection increases the time that the mice spend motionless. This argues that maladaptive strengthening of this connection underlies the paucity of volitional movements, which is a hallmark of Parkinson's disease.