bluuebunny/crossref_metadata_2025_split huggingface dataset:
Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation
Authors: Tzannou Ifigeneia , Papadopoulou Anastasia , Naik Swati , Leung Kathryn , Martinez Caridad A. , Ramos Carlos A. , Carrum George , Sasa Ghadir , Lulla Premal , Watanabe Ayumi , Kuvalekar Manik , Gee Adrian P. , Wu Meng-Fen , Liu Hao , Grilley Bambi J. , Krance Robert A. , Gottschalk Stephen , Brenner Malcolm K. , Rooney Cliona M. , Heslop Helen E. , Leen Ann M. , Omer Bilal 
Published: August 2017

Purpose Improvement of cure rates for patients treated with allogeneic hematopoietic stem-cell transplantation (HSCT) will require efforts to decrease treatment-related mortality from severe viral infections. Adoptively transferred virus-specific T cells (VSTs) generated from eligible, third-party donors could provide broad antiviral protection to recipients of HSCT as an immediately available off-the-shelf product. Patient and Methods We generated a bank of VSTs that recognized five common viral pathogens: Epstein-Barr virus (EBV), adenovirus (AdV), cytomegalovirus (CMV), BK virus (BKV), and human herpesvirus 6 (HHV-6). The VSTs were administered to 38 patients with 45 infections in a phase II clinical trial. Results A single infusion produced a cumulative complete or partial response rate of 92% (95% CI, 78.1% to 98.3%) overall and the following rates by virus: 100% for BKV (n = 16), 94% for CMV (n = 17), 71% for AdV (n = 7), 100% for EBV (n = 2), and 67% for HHV-6 (n = 3). Clinical benefit was achieved in 31 patients treated for one infection and in seven patients treated for multiple coincident infections. Thirteen of 14 patients treated for BKV-associated hemorrhagic cystitis experienced complete resolution of gross hematuria by week 6. Infusions were safe, and only two occurrences of de novo graft-versus host disease (grade 1) were observed. VST tracking by epitope profiling revealed persistence of functional VSTs of third-party origin for up to 12 weeks. Conclusion The use of banked VSTs is a feasible, safe, and effective approach to treat severe and drug-refractory infections after HSCT, including infections from two viruses (BKV and HHV-6) that had never been targeted previously with an off-the-shelf product. Furthermore, the multispecificity of the VSTs ensures extensive antiviral coverage, which facilitates the treatment of patients with multiple infections.
Practice Patterns, Attitudes, and Barriers to Palliative Care Consultation by Gynecologic Oncologists
Authors: Buckley de Meritens Alexandre , Margolis Benjamin , Blinderman Craig , Prigerson Holly G. , Maciejewski Paul K. , Shen Megan J. , Hou June Y. , Burke William M. , Wright Jason D. , Tergas Ana I. 
Published: August 2017

Purpose: We sought to describe practice patterns, attitudes, and barriers to the integration of palliative care services by gynecologic oncologists. Methods: Members of the Society of Gynecologic Oncology were electronically surveyed regarding their practice of incorporating palliative care services and to identify barriers for consultation. Descriptive statistics were used, and two-sample z-tests of proportions were performed to compare responses to related questions. Results: Of the 145 respondents, 71% were attending physicians and 58% worked at an academic medical center. The vast majority (92%) had palliative care services available for consultation at their hospital; 48% thought that palliative care services were appropriately used, 51% thought they were underused, and 1% thought they were overused. Thirty percent of respondents thought that palliative care services should be incorporated at first recurrence, whereas 42% thought palliative care should be incorporated when prognosis for life expectancy is ≤ 6 months. Most participants (75%) responded that palliative care consultation is reasonable for symptom control at any stage of disease. Respondents were most likely to consult palliative care services for pain control (53%) and other symptoms (63%). Eighty-three percent of respondents thought that communicating prognosis is the primary team’s responsibility, whereas the responsibilities for pain and symptom control, resuscitation status, and goals of care discussions were split between the primary team only and both teams. The main barrier for consulting palliative care services was the concern that patients and families would feel abandoned by the primary oncologist (73%). Ninety-seven percent of respondents answered that palliative care services are useful to improve patient care. Conclusion: The majority of gynecologic oncologists perceived palliative care as a useful collaboration that is underused. Fear of perceived abandonment by the patient and family members was identified as a significant barrier to palliative care consult.
Bidding for Multiple Keywords in Sponsored Search Advertising: Keyword Categories and Match Types
Authors: Du Xiaomeng , Su Meng , Zhang Xiaoquan (Michael) , Zheng Xiaona 
Published: August 2017

Although keyword auctions are often studied in the context of a single keyword in the literature, firms generally have to participate in multiple keyword auctions at the same time. Advertisers purchase a variety of keywords that can be categorized as generic-relevant, focal-brand, and competing-brand keywords. At the same time, firms also have to choose how the keywords can be matched to search queries: exact, phrase, or broad. This study empirically examines how keyword categories and match types influence the performance of advertising campaigns. We build a hierarchical Bayesian model to address the endogeneity problem contained in the simultaneous equations of the click-through rate, the conversion rate, cost per click, and rank, and we use the Markov Chain Monte Carlo method to identify the parameters. Our results suggest that it is important to differentiate among the various bidding strategies for various keyword categories and match types. We also report results related to financial performance such as number of sales, profit, and return on investment for different keywords. These findings shed light on the practice of sponsored search advertising by offering insights into how to manage ad campaigns when advertisers have to bid on multiple keywords. The online appendix is available at https://doi.org/10.1287/isre.2017.0724 .
Aportes para pensar la integración docencia, investigación y extensión universitaria, desde una experiencia en el campo “envejecimiento y vejez”
Authors: Ludi María del Carmen , Messina Carina 
Published: August 2017

El objetivo del artículo es compartir algunas reflexiones desde una perspectiva de integración con relación a nuestra práctica docente en las cátedras Intervención Profesional1 y en proyectos de extensión e investigación en el campo“envejecimiento y vejez”.Se trabajan dimensiones que conforman dicha articulación, las que posibilitan mostrar el potencial de generación de conocimiento e intervención de la universidad en cuanto a la realidad social en que se inserta y de la cual forma parte.En el desarrollo de la práctica preprofesional de los estudiantes, la extensión universitaria y la investigación, se constituyen en herramientas fundamentales para el trabajo de diferentes temáticas, en nuestro caso “envejecimiento y vejez”. Especialmente, teniendo en cuenta la inserción en organizaciones institucionales, público estatales y público societales, con las que se comparte la producción de saberes y diseño de estrategias de intervención tendientes a transformar situaciones problemáticas ligadas a las manifestaciones de la cuestión social.
Experiências de convergência entre ensino, pesquisa e extensão na formação inicial de futuros pedagogos
Authors: Medeiros Montanini Cristiane Aparecida , Moreira da Rocha Veiga Adriana 
Published: August 2017

O presente artigo apresenta os resultados do Trabalho de Conclusão do Curso de Pedagogia, a partir de pesquisa desenvolvida e orientada pelas autoras, realizada na Universidade Federal de Santa Maria, no ano de 2014. O objetivo geral foi analisar as experiências vivenciadas na relação entre o ensino, pesquisa e extensão pelos acadêmicos do curso de Pedagogia Licenciatura Plena da própria universidade. A revisão teórica do trabalho abordou os significados do ensino, da pesquisa e da extensão para a formação universitária e as possibilidades de estudos oferecidos no percurso da graduação. Utilizando uma abordagem qualitativa, por meio de questões abertas propostas aos estudantes, a pesquisa colheu relatos das experiências individuais vivenciadas durante o percursoacadêmico. As contribuições dos sujeitos da pesquisa foram analisadas mediante a Análise Textual Discursiva (ATD) proposta por Roque Moraes (2007). Os resultados corroboram com a importância do tripé ensino-pesquisa-extensão na formação e na docência universitária.
Microintervenciones didácticas para la alfabetización de adultos en contextos adversos
Authors: Dallia Micaela , Oggioni Mariana , Rudzki Natasha , Sánchez Lorena , Carrió Cintia 
Published: August 2017

En este artículo se relata la experiencia de aprendizaje mutuo entre un grupo de voluntarios–estudiantes avanzados de la carrera de Letras y un grupo deadultos de una comunidad aborigen. El objetivo del proyecto apuntó a la alfabetización inicial de adultos de la comunidad, quienes no contaban con conocimientos previos o con experiencias escolares mínimas. Con clarospropósitos de interrelación, aprendizaje y reconocimientos de las diferencias culturales, se abordó el trabajo desde una metodología de alfabetización que fuemutando y adaptándose a las necesidades del medio, lo que pone de manifiesto la necesidad de continuo diálogo y retroalimentación entre las tareas de extensión einvestigación. El objetivo concreto, planteado desde el equipo, fue lograr avances básicos en la escritura, en la lectura y la posibilidad de rubricar la propia identidad(el propio yo). El desafío consistió en readaptar las expectativas y sobrellevar los obstáculos sociales, organizativos y epistemológicos. Estos últimos, especialmente, resaltando las tensiones entre formación y actuación de los conocimientos.
El ejercicio del derecho a la educación y la comunicación en la formación universitaria a partir de una propuesta de extensión
Authors: Boeykens Aixa 
Published: August 2017

El Proyecto de Curricularización de la Extensión “Periodismo en la Universidad y la Escuela Secundaria desarrolla producciones comunicacionales entre estudiantes y docentes de ambos niveles educativos. Este proceso de trabajositúa a la extensión como una instancia de diálogos y aprendizajes entre actores e instituciones. Se producen contenidos periodísticos desde una perspectiva queconsidera a la comunicación como un derecho y a los medios como un servicio público. A partir de 2016 y durante 2017 investigaremos qué incidencias tiene laformación en extensión en los estudiantes del ciclo medio y superior. Este trabajo se lleva adelante en el Taller de Producción Periodística de la Licenciatura en Comunicación Social de la Facultad de Ciencias de la Educación de la Universidad Nacional de Entre Ríos en conjunto con la cátedra Sociología de la Educación.
Resultados y desafíos de la educación experiencial en costos y gestión para el Centro de Emprendedores de la Economía Social y Solidaria
Authors: Puccio José , Valli Romina Carola , De Greef Melisa , Fail Alejandra Del Carmen 
Published: August 2017

El presente trabajo tiene la finalidad de analizar y reflexionar sobre una práctica de extensión de educación experiencial desarrollada en la Facultad de CienciasEconómicas de la Universidad Nacional del Litoral. Se realiza un abordaje sobre la implementación de la misma, su vinculación con diversas iniciativas dentro de la Universidad, los resultados y beneficios tanto para los alumnos, como para los docentes y la comunidad a la cual está destinada dicha práctica destacando la importancia de enseñar y aprender de “otra forma”, de relacionar el aprendizaje académico con la vida real y el desarrollo de conciencia social por parte de la comunidad educativa. Los contenidos planteados tienen que ver con los costos yla generación de resultados. Además se describen los inconvenientes detectados y los desafíos para futuras implementaciones de esta enriquecedora experiencia.
Agenda Redes
Authors: Revista de Extensión Universitaria +E 
Published: August 2017

Unión Latinoamericana de Extensión Universitaria (ULEU)Comisión Permanente de Extensión de la Asociación Universidades de Grupo Montevideo (AUGM)Red Nacional de Extensión Universitaria (REXUNI) del Consejo Interuniversitario Nacional (CIN)Universidad Nacional del Litoral (UNL)
Implementasi Kurikulum 2013 pada Anak Berkebutuhan Khusus (ABK) di SD Muhammadiyah Sapen Yogyakarta
Authors: Mayasari Mayasari 
Published: August 2017

This paper seeks to analize the implementation of 2013 Curricula in the case of students with disability at a Muhammadiyah Elementary School in Yogyakarta. The research found that the implementation is done gradually in a way to adapt to the condition of the students. In the teaching process, a student with disability may choose a subject that he/she needs to learn. The learning objectives and outputs can be modified to meet the level of the student’s ability or by adapting the length of learning to be longer than other non-disabled students.The supporting factors include no discrimination among all students of various abilities and the local government support. The challenging factors include the lack of special assistance teachers, the inefficiency in the learning process, and the lack of disability knowledge among the teachers.[Tujuan penelitian ini untuk menganalisis Implementasi Kurikulum 2013 pada ABK di SD Muhammadiyah Sapen, Yogyakarta. Jenis penelitian adalah penelitian kualitatif, dengan pendekatan fenomenologis. Penelitian menemukan bahwa implementasi kurikulum 2013 di SD Muhammadiyah Sapen dilakukan secara bertahap dan disesuaikan dengan gradasi berat atau ringannya kondisi peserta didik. Dalam proses pembelajaran ABK dapat menentukan sendiri tema atau hal yang akan dipelajarinya pada hari tersebut. Selanjutnya untuk penyusunan RPP, khusus untuk anak ABK, SK/KD bisa diturunkan dan disesuaikan berdasarkan kemampuan anak.Faktor pendukung terlaksananya kegiatan ini meliputi adanya kerjasama yang baik antar guru dan orang tua dan adanya dukungan penuh dari pemerintah provinsi dan pemerintah kabupaten/kota. Pemerintah bertanggungjawab dalam mempersiapkan atau memberikan bantuan profesional kepada guru dan kepala sekolah untuk melaksanakan kurikulum di kabupaten/kota terkait. terjalinnya kerjasama yang baik dengan Diknas-diknas, diantaranya Diknas pariwisata. Faktor penghambatnya meliputi, belum tersedianya tenaga khusus untuk penanganan anak tunarungu dan tunagrahita, belum adanya Guru Pendamping Khusus, kurang efisiennya waktu pembelajaran, dan masih kurangnya pemahaman guru tentang penanganan masalah anak-anak ABK.]
Modul Kimia Berbasis EPUB untuk Siswa Tunanetra: Materi Larutan Elektrolit dan Non-Elektrolit
Authors: Satrio Benny Yanuar Dwi 
Published: August 2017

Nowadays, teaching tools, especially for chemistry subject, are limited. Several studies have been conducted to advance the teaching tools through Research and Development approach. The aim of this research is to generate a digital module in chemistry using the subject of electrolyte and non-electrolyte solution through .epub format. This research has been drawn upon procedural development model by Borg and Gall. The development of Epub module of chemistry has been supervised and peer reviewed by senior lecturers (expert in material and media subject) and senior high school teachers of student with special needs by considering the perspective of student with visual disabilities. The chemistry module has been assessed and scored by material experts with percentage of 87.14% which represents very good quality, whereas the media experts score 85,45% which means a very good quality. According to high school teachers for student with visual disabilities’, the score is 86.4%. The score from 7 students with visual disabilities shows 94% which signifies a very good quality of chemistry module.[Saat ini, media pembelajaran khususnya untuk mata pelajaran kimia masih terbatas. Berbagai studi telah dilakukan untuk mengembangkan media pembelajaran melalui metode Research and Development (R&D). Tujuan penelitian untuk menghasilkan modul digital kimia dengan materi pokok larutan elektrolit dan non elektrolit dalam format .epub. Penelitian telah dilakukan dengan model pengembangan prosedural oleh Borg dan Gall. Pengembangan epub modul kimia dibimbing oleh dosen pembimbing dan mendapatkan penilaian dari peer reviewers, dosen ahli (ahli materi dan ahli media), guru siswa difabel netra, dan siswa difabel netra. Hasil penelitian menunjukkan bahwa modul kimia yang dikembangkan, menurut penilaian ahli materi mendapatkan persentase keidealan 87,14% dan kualitas Sangat Baik (SB), sedangkan menurut penilaian ahli media mendapatkan skor persentase keidealan 85,45% dan kualitas Sangat Baik (SB). Berdasarkan penilaian guru siswa difabel netra SMA/MA, modul kimia mendapatkan persentase keidealan 86,40% dan kualitas Sangat Baik (SB) dan berdasarkan respons tujuh siswa difabel netra mendapatkan persentase keidealan 94%.]
Foreign language learning anxiety of foreign students while learning Turkish as a foreign language<p>Türkçeyi yabancı dil olarak öğrenen yabancı uyruklu öğrencilerde yabancı dil öğrenme kaygısı
Authors: Yalçın Süleyman Barbaros , Sarıgül Ece 
Published: August 2017

The aim of this study is to examine the anxiety levels of foreign students towards Turkish language , to determine their relations with the four main language skills ( writing , speaking, listening, reading) which are generally accepted as the main language skills, to determine the other difficulties they face while learning a foreign language, to diagnose continuity condition of the anxiety after they have started learning Turkish and finding out possible solutions for the issues sourcing from anxiety. The participants of this research are 19 students who studied at different departments of Necmettin Erbakan University in 2016-2017 academic year.They all participated the study voluntarily. The qualitative research model has been used as a research model in this study. A semi-structured interview form developed by the researches containing 6 open ended questions has been used as a data collection tool. The main results and themes that are obtained from data analysis can be summarized as follows: anxiety theme during the the process of learning Turkish, language , language proficency theme, strategy themes during language learning process, linguistic competencies theme, effects of social environment theme and motivational contributions of the instructors’ theme. There are also some suggestions both for language teachers and learners in the conclusion part of the study.Extended English abstract is in the end of PDF (TURKISH) file.ÖzetBu çalışmada, yabancı dil olarak Türkçe öğrenen bireylerde bulunan Türkçe öğrenmeye ilişkin kaygıların neler olduğunun ortaya konması; bu kaygıların, dilin dört temel becerisi yazma, konuşma, dinleme ve okuma becerilerinin hangileri ile ilgili olduğunun belirlenmesi, yabancı dil öğrenmede karşılaştıkları diğer sorunların saptanması, Türk dilini öğrenmeye başladıktan sonra bu kaygılarının ve sorunlarının devam edip etmediğinin tespit edilmesi, devam eden kaygılarının ve sorunlarının hangi aşamada olduğu, tespit edilen kaygı ve sorunların çözümüne yönelik önerilerin ortaya konması amaçlanmıştır.Buna yönelik olarak araştırmada, Necmettin Erbakan Üniversitesi’nde 2016-2017 öğretim yılında Türkçe öğrenim gören 19 yabancı uyruklu öğrenciyle çalışılmıştır. Araştırma nitel araştırma yöntemi ile gerçekleştirilmiştir. Çalışmada veri toplama aracı olarak ise araştırmacılar tarafından hazırlanmış olan 6 açık uçlu soruyu içeren yarı yapılandırılmış görüşme formu kullanılmıştır. Verilerin analizi sonucunda elde edilen öncelikli temalar şunlardır: Türkçe öğrenme sürecinde yaşanan kaygı temaları, dil yeterliliği temaları, sosyal çevrenin etkisi temaları, öğrenme sürecindeki strateji temaları ve motivasyon temaları olarak belirlenmiştir. Çalışmanın sonuç bölümünde ise hem öğrencilere hem de öğretim elemanlarına önerilerde bulunulmuştur.// Annotate Highlight
Sustainability of green jobs in Portugal: a methodological approach using occupational health indicators
Authors: Moreira Sandra , Vasconcelos Lia , Santos Carlos Silva 
Published: August 2017

Abstract

Objective
This study aimed to develop a methodological tool to analyze and monitor the green jobs in the context of Occupational Health and Safety.

Methods
A literature review in combination with an investigation of Occupational Health Indicators was performed. The resulting tool of Occupational Health Indicators was based on the existing information of “Single Report” and was validated by national’s experts.

Results
The tool brings together 40 Occupational Health Indicators in four key fields established by World Health Organization in their conceptual framework “Health indicators of sustainable jobs. ” The tool proposed allows for assessing if the green jobs enabled to follow the principles and requirements of Occupational Health Indicators and if these jobs are as good for the environment as for the workers’ health, so if they can be considered quality jobs.

Conclusions
This shows that Occupational Health Indicators are indispensable for the assessment of the sustainability of green jobs and should be taken into account in the definition and evaluation of policies and strategies of the sustainable development.
Preventive measures and lifestyle habits against exertional heat illness in radiation decontamination workers
Authors: Endo Shota , Kakamu Takeyasu , Sato Sei , Hidaka Tomoo , Kumagai Tomohiro , Nakano Shinichi , Koyama Kikuo , Fukushima Tetsuhito 
Published: August 2017

Abstract

Objectives
The aim of this study was to reveal the current state of preventive measures and lifestyle habits against heat illness in radiation decontamination workers and to examine whether young radiation decontamination workers take less preventive measures and have worse lifestyle habits than the elder workers.

Methods
This was a cross-sectional study. Selfadministered questionnaires were sent to 1,505 radiation decontamination workers in Fukushima, Japan. Five hundred fifty-eight men who replied and answered all questions were included in the statistical analysis. The questionnaire included age, duration of decontamination work, previous occupation, lifestyle habit, and preventive measures for heat illness. We classified age of the respondents into five groups: &lt;30, 30-39, 40-49, 50-59, and ≥60 years and defined the workers under 30 years of age as young workers. Logistic regression analysis was used to reveal the factors associated with each lifestyle habit and preventive measures.

Results
In comparison with young workers, 50-59-year-old workers were significantly associated with refraining from drinking alcohol. Workers 40 years of age or older were significantly associated with cooling their bodies with refrigerant. Furthermore, 30-39-year-old workers and 40-49-year-old workers were significantly associated with adequate consumption of water compared to young workers.

Conclusion
The results of our study suggests that young decontamination workers are more likely to have worse lifestyle habits and take insufficient preventive measures for heat illness. This may be the cause of higher incidence of heat illness among young workers.