bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possible Involvement of the CACNA1E Gene in Migraine: A Search for Single Nucleotide Polymorphism in Different Clinical Phenotypes
Authors: Ambrosini Anna , D'Onofrio Mara , Buzzi Maria Gabriella , Arisi Ivan , Grieco Gaetano S. , Pierelli Francesco , Santorelli Filippo M. , Schoenen Jean 
Published: June 2017

ObjectiveTo search for differences in prevalence of a CACNA1E variant between migraine without aura, various phenotypes of migraine with aura, and healthy controls.BackgroundFamilial hemiplegic migraine type 1 (FHM1) is associated with mutations in the CACNA1A gene coding for the alpha 1A (Cav2.1) pore‐forming subunit of P/Q voltage‐dependent Ca2+ channels. These mutations are not found in the common forms of migraine with or without aura. The alpha 1E subunit (Cav2.3) is the counterpart of Cav2.1 in R‐type Ca2+ channels, has different functional properties, and is encoded by the CACNA1E gene.MethodsFirst, we performed a total exon sequencing of the CACNA1E gene in three probands selected because they had no abnormalities in the three FHM genes. In a patient suffering from basilar‐type migraine, we identified a single nucleotide polymorphism (SNP) in exon 20 of the CACNA1E gene (Asp859Glu – rs35737760; Minor Allele Frequency 0.2241) hitherto not studied in migraine. In a second step, we determined its occurrence in four groups by direct sequencing on blood genomic DNA: migraine patients without aura (N = 24), with typical aura (N = 55), complex neurological auras (N = 19; hemiplegic aura: N = 15; brain stem aura: N = 4), and healthy controls (N = 102).ResultsThe Asp859Glu – rs35737760 SNP of the CACNA1E gene was present in 12.7% of control subjects and in 20.4% of the total migraine group. In the migraine group it was significantly over‐represented in patients with complex neurological auras (42.1%), OR 4.98 (95% CI: 1.69‐14.67, uncorrected P = .005, Bonferroni P = .030, 2‐tailed Fisher's exact test). There was no significant difference between migraine with typical aura (10.9%) and controls.ConclusionsWe identified a polymorphism in exon 20 of the CACNA1E gene (Asp859Glu – rs35737760) that is more prevalent in hemiplegic and brain stem aura migraine. This missense variant causes a change from aspartate to glutamate at position 859 of the Cav2.3 protein and might modulate the function of R‐type Ca2+ channels. It could thus be relevant for migraine with complex neurological aura, although this remains to be proven.
A transnational history of Pentecostalism in West Africa
Authors: Osinulu Adedamola 
Published: June 2017

AbstractOver the past 3 decades, there has been a noticeable increase in the popularity of Pentecostal and Charismatic Christianity in parts of West Africa evident in the proliferation of Pentecostal and Charismatic churches in the region. This paper explores the roots of that movement starting with the arrival of Christianity in West Africa and traces the various transformations that have led up to the current wave of Pentecostal and Charismatic renewal. In compliance with the polycentric hypothesis of origin for the global Pentecostal movement, this paper looks at the actors, organizations, and events that catalyzed and shaped the movement in West Africa starting with the itinerant African preachers that led revival moments at the start of the twentieth century. As such figures like William Wade Harris, Garrick Sokari Braide, Joseph Ayo Babalola, Benson A. Idahosa (Church of God Mission International), Enoch A. Adeboye (Redeemed Christian Church of God), David O. Oyedepo (Living Faith Church Worldwide a.k.a. Winners Chapel International), and Mensa Otabil (International Central Gospel Church) are discussed. Furthermore, the paper argues that rather than viewing Pentecostal organizations in various West African countries as solely independent developments or alternatively as local eruptions of global phenomena, we should view them as part of a regional process of exchanges of discourses and practices by Africans across national borders based on shared political and cultural histories. Particular attention is paid to goings on in Nigeria and Ghana where the Pentecostal and Charismatic movement have had the greatest impact.
Designing service system networks with interruption risks
Authors: Hoseinpour Pooya , Ahmadi‐Javid Amir 
Published: June 2017

AbstractThis paper incorporates interruption risk into designing the network of an immobile service system. The service system consists of service facilities, each serving a set of allocated demand locations. The open facilities may be interrupted randomly because of a variety of facility‐induced risk factors. The goal is to determine which service facilities are established, what service capacities are selected at open facilities, and how to assign the customers to the open facilities in order to maximize the system's overall performance. The problem is formulated as an integer nonlinear programming model and solved by a Lagrangian relaxation algorithm. The numerical experiments illustrate the high performance of the algorithm in large scales. Several managerial implications are also presented to show the effects of service interruption risks.
Detection of desmoplastic melanoma with dermoscopy and reflectance confocal microscopy
Authors: Maher N.G. , Solinas A. , Scolyer R.A. , Puig S. , Pellacani G. , Guitera P. 
Published: June 2017

AbstractBackgroundDesmoplastic melanoma (DM) is frequently misdiagnosed clinically and often associated with melanoma in situ (MIS).ObjectiveTo improve the detection of DM using dermoscopy and reflectance confocal microscopy (RCM).MethodsA descriptive analysis of DM dermoscopy features and a case–control study within a melanoma population for RCM feature evaluation was performed blindly, using data obtained between 2005 and 2015. After retrospectively identifying all DM cases with RCM data over the study period (n = 16), a control group of non‐DM melanoma patients with RCM data, in a ratio of at least 3 : 1, was selected. The control group was matched by age and primary tumour site location, divided into non‐DM invasive melanomas (n = 27) and MIS (n = 27). Invasive melanomas were selected according to the melanoma subtypes associated with the DM cases. The main outcomes were the frequency of melanoma‐specific features on dermoscopy for DM; and the odds ratios of RCM features to distinguish DM from MIS and/or other invasive melanomas; or MIS from the combined invasive melanoma group.ResultsAt least one of the 14 melanoma‐specific features evaluated on dermoscopy was found in 100% of DMs (n = 15 DM with dermoscopy). Known RCM melanoma predictors were commonly found in the DMs, such as pagetoid cells (100%) and cell atypia (100%). The RCM feature of spindle cells in the superficial dermis was more common in DM compared with the entire melanoma control group (OR 3.82, 95% CI 1.01–14.90), and particularly compared to MIS (OR 5.48, 95% CI 1.11–32.36). Nucleated cells in the dermis and the RCM correlate of dermal inflammation were also significant RCM features favouring DM over MIS, as well as invasive melanoma over MIS.ConclusionDermoscopy and RCM may be useful tools for the identification of DM. Certain RCM features may help distinguish DM from MIS and other invasive melanomas. Larger studies are warranted.
CT versus MR Techniques in the Detection of Cervical Artery Dissection
Authors: Hanning Uta , Sporns Peter B. , Schmiedel Meilin , Ringelstein Erich B. , Heindel Walter , Wiendl Heinz , Niederstadt Thomas , Dittrich Ralf 
Published: June 2017

ABSTRACTBACKGROUNDSpontaneous cervical artery dissection (sCAD) is an important etiology of juvenile stroke. The gold standard for the diagnosis of sCAD is convential angiography. However, magnetic resonance imaging (MRI)/MR angiography (MRA) and computed tomography (CT)/CT angiography (CTA) are frequently used alternatives. New developments such as multislice CT/CTA have enabled routine acquisition of thinner sections with rapid imaging times. The goal of this study was to compare the capability of recent developed 128‐slice CT/CTA to MRI/MRA to detect radiologic features of sCAD.METHODSRetrospective review of patients with suspected sCAD (n = 188) in a database of our Stroke center (2008‐2014), who underwent CT/CTA and MRI/MRA on initial clinical work‐up. A control group of 26 patients was added. All Images were evaluated concerning specific and sensitive radiological features for dissection by two experienced neuroradiologists. Imaging features were compared between the two modalities.RESULTSForty patients with 43 dissected arteries received both modalities (29 internal carotid arteries [ICAs] and 14 vertebral arteries [VAs]). All CADs were identified in CT/CTA and MRI/MRA. The features intimal flap, stenosis, and lumen irregularity appeared in both modalities. One high‐grade stenosis was identified by CT/CTA that was expected occluded on MRI/MRA. Two MRI/MRA‐confirmed pseudoaneurysms were missed by CT/CTA. None of the controls evidenced specific imaging signs for dissection.CONCLUSIONSCT/CTA is a reliable and better available alternative to MRI/MRA for diagnosis of sCAD. CT/CTA should be used to complement MRI/MRA in cases where MRI/MRA suggests occlusion.
What is the Role of Experience in Children's Success in the False Belief Test: Maturation, Facilitation, Attunement or Induction?
Authors: Fenici Marco 
Published: June 2017

AbstractAccording to a widely shared view, experience plays only a limited role in children's acquisition of the capacity to pass the false belief test: at most, it facilitates or attunes the development of mindreading abilities from infancy to early childhood. Against the facilitation—and also the maturation—hypothesis, I report empirical data attesting that children and even adults never come to understand false beliefs when deprived of proper social and linguistic interaction. In contrast to the attunement hypothesis, I argue that alleged mindreading abilities in infancy differ significantly from those required to pass the false belief test at age four. I conclude that children's success in the false belief test reflects the acquisition of a novel psychological competence, and argue that social experience in the form of conversation about mental states teaches children to exploit belief reports to predict intelligent behaviour, and induces their acquisition of a capacity to recognize and track others' beliefs across contexts.
A day in the life of a dolphin: Using bio‐logging tags for improved animal health and well‐being
Authors: Alex Shorter K. , Shao Yunli , Ojeda Lauro , Barton Kira , Rocho‐Levine Julie , van der Hoop Julie , Moore Michael 
Published: June 2017

AbstractLittle quantitative information on the behavior, health, and activity level of managed marine mammals is currently collected, though it has the potential to significantly contribute to management and welfare of these animals. To address this, high‐resolution motion‐sensing digital acoustic recording tags (DTAGs) collected data from animals under human care (n = 5) during their daily routine, and classification algorithms were used for gait analysis and event detection. We collected and examined ~57 h of data from five bottlenose dolphins (Tursiops truncatus). Day‐scale changes in behavior and activity level were observed and diurnal changes were detected with lower activity at night (n = 1). During the day, animals spent about 70% of their time swimming. The deepest part of the lagoon is ~3 m and individual dives were typically shallow (~1 m) with the dolphins tending to utilize a fluke and glide gait pattern. Activity level was quantified using overall dynamic body acceleration. A significant relationship between normalized activity level and glide duration during different portions of the dive was measured; animals fluked more during descent and glided more during ascent. This could indicate that even during very shallow dives the dolphins use their positive buoyancy to improve energy economy.
An ameloblastoma associated with cardiofaciocutaneous syndrome
Authors: Toole J. , Napier S. , Marley J. 
Published: June 2017

AbstractThis case describes the management of a plexiform unicystic ameloblastoma in a child with cardiofaciocutaneous syndrome. This was managed conservatively, which has allowed the patient to undergo normal dental development. There are no signs of recurrence 4 years post‐operatively and the use of magnetic resonance imaging in monitoring has ensured the patient's exposure to ionising radiation is minimised. The patient's cardiofaciocutaneous syndrome was linked to a BRAF mutation. This gene is involved in cell proliferation and has recently been shown to have a link with mandibular ameloblastomas. As far as the authors are aware, this is the published first case of an ameloblastoma in a patient with cardiofaciocutaneous syndrome.
Migrant domestic workers and shifting strategies in organizing
Authors: Pérez Nancy 
Published: June 2017

AbstractThe mobilization of domestic workers in the United States has strengthened and grown nationally in the last 15 years, and scholars have been paying particular attention to the ways their organizing has undertaken innovative strategies to address social, cultural, and legal exclusions specific to migrant domestic workers. Research has focused on historicizing the entrenched colonial legacy of servitude and domesticity, but more recently studies have concentrated on documenting the challenges and victories domestic workers have achieved as a result of their legislative state campaigns for a Domestic Worker Bill of Rights. This article reviews recent research that analyzes the complex strategies employed in organizing, and the role that migrant domestic workers play in challenging the boundaries of citizenship and integrating a transnational dimension to domestic worker organizing. Although research shows that enforcement continues to be a central issue in states where a Domestic Workers Bill of Rights has been enacted, migrant domestic workers continue to strengthen the coalitional power that has shown to transform new directions in organizing that demand alternate ways of contemplating workers experiences as generating different principles of justice.
Punishment and status in collective action: How status hierarchiesfoster optimal punishment use
Authors: Vincent Aaron 
Published: June 2017

AbstractI provide a brief overview of the literature on human cooperation, punishment, and social dilemmas. After reviewing relevant literature, I move on to a series of predictions, intertwining findings on punishment, public goods, and social status. Leaning onStatus Characteristics Theory, I explicate how the behavioral expectations that we derive from status positions foster a means of using punishment to secure public goods. Furthermore, I argue that we carry general expectations for high status actors to punish when deemed collectively necessary. Building on this expectation, I articulate how initially status‐homogenous groups can develop status ranks on the basis of punishment behavior, allowing task groups to mimic sanctioning institutions commonly seen in public goods research and everyday life.
The Social‐psychological Aspects of Team Formation: New Avenues for Research
Authors: Bailey Jasmón L. , Skvoretz John 
Published: June 2017

AbstractThe ubiquity of teams in the modern workplace cannot be denied, as Curseu, Kenis, and Raab (2009, p. 30) note, “team formation is a challenge in modern organizations as most of them use teams to perform a variety of organizational tasks.” How teams form is, therefore, a question of much practical interest. Research illustrates that stratified social systems influence the choice and decision‐making behaviors that shape group and team formation (Hechter, 1978). From a structural social psychological perspective (Sell & Kuipers, 2009; Lawler, Ridgeway, and Markovsky, 1993), teams are like microcosmic societies. They represent a process of social cohesion through interaction. Additionally, they can be organic, mechanical, homogeneous, and heterogeneous. In other words, teams are structural and cultural artifacts of societies. Members of society through interaction create these “social artifacts,” which may consist of hierarchically organizing sets of individuals into a group, or multiple groups, relative to power and status dimensions. In this paper, we aim to show how contributions from social psychology have informed research on team formation. Thus, two research questions guide this paper: What are the mechanisms of team formation via partner selection for self‐organizing teams? In what ways, can these studies advance scholarship focusing on the social psychology of inequality? To establish a foundation for understanding the various studies on team formation, we begin with a general overview on how team and team formation has been conceptualized. Next, we examine the social psychological research on team formation via partner selection. In doing so, we note the importance given to the 4 major mechanisms of team formation emerging from the literature: competence, homophily, familiarity, and affect. Lastly, we conclude the paper with a discussion addressing the research questions guiding this paper and suggest opportunities for social psychologists to consider for future team formation studies.
Complete Genomic Sequence of
Dengue virus 1
, Isolated from Plasma Collected from a Haitian Child in 2014
Authors: Elbadry Maha , White Sarah , Loeb Julia , Tagliamonte Massimiliano , Salemi Marco , Beau De Rochars J. Valery Madsen , Okech Bernard , Morris Glenn , Lednicky John 
Published: June 2017

ABSTRACT

An outbreak of dengue fever followed a chikungunya fever outbreak in Haiti in 2014. We detected
Dengue virus 1
(DENV-1) in plasma samples collected between May 2014 and February 2015. A representative isolate was fully sequenced, and phylogenetic analyses indicate that it groups within the genotype V South American and Caribbean DENV-1 clades.
Genome Sequence of Escherichia coli E28, a Multidrug-Resistant Strain Isolated from a Chicken Carcass, and Its Spontaneously Inducible Prophage
Authors: Schmidt Imke , Riedel Thomas , Schober Isabel , Bunk Boyke , Spröer Cathrin , Bierbrodt Anna , Lehnherr Hansjörg , Wittmann Johannes 
Published: June 2017

ABSTRACT

In this study, we sequenced the complete genome of the multidrug-resistant
Escherichia coli
strain E28, which was used as an indicator strain for phage therapy
in vivo
. We used a combination of single-molecule real-time and Illumina sequencing technology to reveal the presence of a spontaneously inducible prophage.
Complete Genome Sequence of Veillonella atypica OK5, the First Transformable Strain in the Species
Authors: Zhou Peng , Xie Gary , Li Xiaoli , Liu Jinman , Qi Fengxia 
Published: June 2017

ABSTRACT

The
Veillonella atypica
strain OK5 was isolated from a human saliva sample and was the first strain shown to be genetically transformable in the
Veillonella
genus. Genetic studies using this strain have helped us gain much insight into the ecology of human oral biofilms. Here, we report the complete genome sequence of
V. atypica
OK5.
Complete Genome of a Panresistant Pseudomonas aeruginosa Strain, Isolated from a Patient with Respiratory Failure in a Canadian Community Hospital
Authors: Xiong Jianhui , Déraspe Maxime , Iqbal Naeem , Krajden Sigmund , Chapman William , Dewar Ken , Roy Paul H. 
Published: June 2017

ABSTRACT

We report here the complete genome sequence of a panresistant
Pseudomonas aeruginosa
strain, isolated from a patient with respiratory failure in Canada. No carbapenemase genes were identified. Carbapenem resistance is attributable to a frameshift in the
oprD
gene; the basis for colistin resistance remains undetermined.
Physical and spectroscopic studies on manganese ions in lead halo borate glasses
Authors: Sekhar K. Chandra , Hameed Abdul , Ramadevudu G. , Chary M. Narasimha , Shareefuddin Md. 
Published: June 2017

Lead halo borate glass systems containing manganese ions have been investigated to study the role of halide ions on the physical, optical and EPR studies. The amorphous phase of the prepared glass samples [Formula: see text]PbX2–(30[Formula: see text])PbO–69.5B2O3–0.5MnO2 with X = F, Cl and Br and [Formula: see text] mol% was confirmed from their X-ray diffraction spectra. Ionic radii of the halides played an important role in the physical properties. From the optical absorption spectra, optical band gap and Urbach energy values were evaluated. The EPR spectra have shown a six-line hyperfine (HF) structure centered at [Formula: see text] and attributed to Mn[Formula: see text] centers in octahedral symmetry. The other signals at [Formula: see text] and 4.3 were attributed to the rhombic surroundings of Mn[Formula: see text] ions. The negative shift in [Formula: see text]-value revealed highly ionic environment around the Mn[Formula: see text] ion in the glass hosts. The HF splitting constant (A), number of spins (N) and susceptibility [Formula: see text] values of the prepared glasses were also reported.
Experimental intermittent ischemia augments exercise-induced inflammatory cytokine production
Authors: Shill Daniel D. , Polley Kristine R. , Willingham T. Bradley , Call Jarrod A. , Murrow Jonathan R. , McCully Kevin K. , Jenkins Nathan T. 
Published: June 2017

Acute exercise-induced inflammation is implicated in mediating the beneficial adaptations to regular exercise. Evidence suggests that reduced oxygen and/or blood flow to contracting muscle alters cytokine appearance. However, the acute inflammatory responses to hypoxic/ischemic exercise have been documented with inconsistent results and may not accurately reflect the ischemia produced during exercise in patients with ischemic cardiovascular diseases. Therefore, we determined the extent to which local inflammation is involved in the response to ischemic exercise. Fourteen healthy males performed unilateral isometric forearm contractions for 30 min with and without experimental ischemia. Blood was drawn at baseline, 5 and 10 min into exercise, at the end of exercise, and 30, 60, and 120 min after exercise. Oxygen saturation levels, as measured by near-infrared spectroscopy, were reduced by 10% and 41% during nonischemic and ischemic exercise, respectively. Nonischemic exercise did not affect cytokine values. Ischemia enhanced concentrations of basic fibroblast growth factor, interleukin (IL)-6, IL-10, tumor necrosis factor-alpha, and vascular endothelial growth factor during exercise, but IL-8 was not influenced by ischemic exercise. In conclusion, the present study demonstrates that ischemic, small-muscle endurance exercise elicits local inflammatory cytokine production compared with nonischemic exercise. NEW & NOTEWORTHY We demonstrate that ischemic, small-muscle endurance exercise elicits local inflammatory cytokine production compared with nonischemic exercise. The present study advances our knowledge of the inflammatory response to exercise in a partial ischemic state, which may be relevant for understanding the therapeutic effects of exercise training for people with ischemic cardiovascular disease-associated comorbidities.