bluuebunny/crossref_metadata_2025_split huggingface dataset:
B - 25 Documenting the Prevalence of Sleep Disturbances among TBI Survivors: a FITBIR Study
Authors: Caicedo Mariana Rincon , Punt Stephanie E , Hamilton Nancy 
Published: September 2024

Abstract

Objective
The objective of this study is to utilize data from the Federal Interagency Traumatic Brain Injury Research (FITBIR) database to document the short-term prevalence of sleep disorders among a sample of mild Traumatic Brain Injury (mTBI) survivors.

Method
Data was extracted from the FITBIR website. Adult individuals who sustained an mTBI (Rivermead Post Concussion Symptoms Questionnaire; RPQ6) and had a data collection timepoint within 10 days of the injury were included. Measures of demographic characteristics and sleep problems (Pittsburgh Sleep Quality Index; PSQI) were utilized. A total of 74 participants (97% male, 73% white, mean age = 22.49 SD = 11.25) were included. Descriptive analysis were conducted to document the prevalence of sleep problems among this sample.

Results
Across our sample, broad sleep difficulties were common (PSQI Mean = 7.014, Median = 5, SD = 7.56). 47.29% of participants reported severe sleep difficulties (PSQI &gt;5). 14(23.3%) individuals met criteria for insomnia based on their component 5 scores. Among individuals with a bed partner, only 3(7%) endorsed long breathing pauses, suggestive of Central Sleep Apnea (CSA), 16(40%) endorsed snoring, suggestive of Obstructive Sleep Apnea, and 16(22%) endorsed leg twitching, possibly indicative of Restless Leg Syndrome.

Conclusion
This study highlights the prevalence of sleep problems as a salient issue among mTBI patients. The FITBIR is a valuable tool to further TBI research. Future studies should examine the temporal trajectory of sleep problems and its relationship to other outcomes and include more diverse samples.
B - 29 Exploring Sex Differences in Concussion Symptom Reporting between Parents and Children
Authors: Gordon Taryn , Franke Michelle , Thorne Shaylyn , Black Jacy , Burkhart Scott 
Published: September 2024

Abstract

Objective
Concussion evaluation often entails patient completion of symptom checklists and questionnaires. Prior research indicates children often report higher concussion-related symptoms than parents (Johnson et al., 2020; Liu & Hicks, 2020). Furthermore, research indicates sex differences in reported symptoms among children and adolescents. (Preiss-Farzanegan et al., 2009; Frommer et al., 2011). This study aimed to explore these differences and the relationship between self-reported and parent-reported concussion symptoms by sex.

Methods
Children who sustained a concussion were examined in an acute concussion clinic for diagnosis and treatment of injury. In addition to the physical examination, parents were given the Post-Concussion Symptom Inventory Parent Assessment Form (PCSI-P) and children were given the appropriate version of the PCSI based on their age.

Results
44 children (M = 14.05, SD = 2.49; sex: 12 male, 32 female) and 36 parents were included for analysis. Parents reported higher tiredness (M = 3.4, SD = 1.72) than children self-report (M = 2.57, SD = 1.88; t(34) = 2.84, p = 0.007), and higher irritability (M = 3.03, SD = 2.07) children self-report (M = 2.06, SD = 2.17; t(34) = 2.78, p = 0.009). In male and female self-report, males reported higher levels of feeling dazed (M = 3.33, SD = 1.75) than females (M = 1.58, SD = 1.74; t(28) = 2.20, p = 0.036),and higher levels of slowed response (M = 4.00, SD = 1.23) than females (M = 2.13, SD = 1.96; t(27) = 2.04, p = 0.05). No differences were found between parent reports of male and female children.

Conclusion
Our findings highlight discrepancies between parent and child reports of concussion-related symptoms, emphasizing the need for self and parent report assessments in clinical concussion evaluations. Furthermore, sex differences in self-reported symptoms underscore the importance of considering sex-related factors in concussion management and treatment.
B - 34 Brain Network Organization over Time after TBI
Authors: Mullin Hollie AC , Hillary Frank G 
Published: September 2024

Abstract

Objective
Resting-state functional magnetic resonance (rsfMRI) has identified that brain networks become less specialized through declining network segregation as people age. Yet, it is unclear how segregation progresses over time after traumatic brain injury (TBI). This study evaluated segregation in older adults (M = 64.17 years) over a 2-year time period to better understand this phenomenon.

Method
45 participants with TBI (mild-complicated, moderate, and severe) and 41 healthy controls (HCs) received a 20-minute rsfMRI scan at timepoint one, and 25 TBI and 15 HCs received a scan at timepoint two. Data were preprocessed with fMRIPrep. XCP_D was used to divide the brain into 274 regions (19 networks) and 1000 regions (17 networks) using the Brainnetome and Schaefer 1000 atlases. Fisher r-to-z transformed connectivity matrices were used to calculate segregation (strength of connections within a network relative to strength of connections between networks).

Results
Segregation didn’t differ significantly (p &gt; 0.05) between the TBI and HC groups at either timepoint, nor did segregation differ between the TBI group’s first and second timepoint. Segregation did significantly decline between the HC group’s first and second timepoint, but this was only observed using the Schaefer 1000 atlas, t(21.46) = −2.09, p = 0.049 95% CI [−0.049, −0.0001].

Conclusions
The results indicate that brain network segregation remains relatively stable after TBI but declines in healthy, older adults over time. This suggests brain network organization is less flexible post-injury and could potentially serve as a brain biomarker. However, it’s worth noting that choice of brain atlas affects the observation of this finding.
B - 38 Concussion Clinical Outcomes and Recovery Time in Individuals with Pre-Existing Anxiety and/or Depression
Authors: Kegel Nathan E , Anish Eli J , Zynda Aaron J , Giordano Elizabeth G , Todd Madeleine G , Miller Maggie E , Collins Michael , Kontos Anthony P 
Published: September 2024

Abstract

Objective
Post-injury anxiety and mood difficulties are common symptoms following concussion. However, limited research has explored the impact of anxiety and/or depression history on individuals’ clinical outcomes and recovery time post- concussion. This study aims to determine the influence of anxiety and/or depression history on individuals’ clinical outcomes and examine outcomes of those with both anxiety and depression history.

Method
We conducted a retrospective review of 297 concussed patients. All participants completed a clinical interview, Immediate Post-Concussion Assessment and Cognitive Test (ImPACT), Clinical Profile Screen (CP-Screen), and Vestibular/Ocular-Motor Screening (VOMS). Participants were categorized into one of three anxiety-depression subgroups — no anxiety or depression history (NONE), anxiety or depression history (EITHER), or anxiety and depression history (BOTH)— based on clinical interviews.

Results
The BOTH group reported higher symptom burden (CP Screen Total Score; p &lt; 0.001) and performed worse on ImPACT Visual Memory (p = 0.03) compared to NONE and EITHER groups. Overall, recovery time differed significantly between groups (p = 0.006). The NONE group recovered significantly faster than the EITHER group (p = 0.04), and the BOTH group (p = 0.03). However, no significant difference in recovery time was noted between the EITHER and BOTH groups (p = 0.58).

Conclusions
Our results suggest that anxiety/depression history is associated with more severe post-concussion symptoms, worse visual memory, and longer recovery times when compared to those with no history of anxiety or depression. These findings highlight the importance of screening for anxiety and depression history in clinical settings and exploring ways to improve concussion recovery for individuals with anxiety and/or depression history.
B - 39 Resilience in Active Duty US Military Service Members: Factor Analysis and Prediction of Psychological Symptoms in a Mild Traumatic Brain Injury Sample
Authors: Hershaw Jamie , Tra John 
Published: September 2024

Abstract

Objective
The factor structure of the Connor-Davidson Resilience Scale (CD-RISC) varies between cultures, settings, and samples, yet has not been assessed in an active-duty United States (US) military sample. We used factor analysis to characterize resilience in a generalizable sample of active-duty service members (ADSMs) and explored its associations with self-reported psychological outcomes in ADSMs with a history of mild traumatic brain injury (mTBI).

Method
Exploratory factor analysis (EFA) of the 25-item CD-RISC was performed on a non-clinical convenience sample of 212 active duty SMs followed by a confirmatory factor analysis (CFA) for model validation. Hierarchical regressions compared the relationships among the resulting factors and total scores on the Post Traumatic Stress Disorder Checklist (PCL-5), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI) between subgroups with self-reported history of mTBI (n = 60) and TBI-negative controls (n = 54).

Results
EFA returned a 4-factor, 19-item solution. After modifications to improve model fit, CFA validated a 4-factor, 17-item solution: Fortitude, Resoluteness, Decisiveness, and Dedication. The interaction of TBI history with the Decisiveness and Dedication factors significantly predicted BDI and PCL-5 total scores (p &lt; 0.05), but not BAI total scores. Fortitude and Resoluteness did not differentially predict any psychological outcomes between groups.

Conclusion
Four latent factors of resilience that are unique to ADSMs were identified and validated from the 25-item CD-RISC. Decisiveness and Dedication more strongly predicted depressive and PTSD symptoms in ADSMs with a history of mTBI than in controls, suggesting these factors of resilience are especially critical for better psychological outcomes following mTBI in military populations.
B - 55 Diffusion Tensor Imaging Analysis of Former American Football Players Exposed to Repetitive Head Impacts
Authors: Wickham Alana , Adler Charles , Alosco Michael , Arciniega Hector , Balcer Laura , Bernick Charles , Bouix Sylvain , Cummings Jeffrey , Koerte Inga , Lin Alexander , Reiman Eric , Shenton Martha , Stern Robert , Breedlove Katherine , Carrington Holly , Coleman Michael , Daneshvar Daniel , John Omar , Jung Leonard , Kim Nicholas , Tripodis Yorgos , Tuz-Zahra Fatima , Wiegand Tim 
Published: September 2024

Abstract

Objective
Exposure to repetitive head impacts (RHI) has been linked to Chronic Traumatic Encephalopathy (CTE) and neuropathological alterations such as white matter shear injuries. In this study, we use diffusion-tensor imaging (DTI) to investigate in vivo white matter alterations among former American football players. We also investigate how age and factors associated with RHI exposure influence white matter integrity.

Methods
We analyzed data from the DIAGNOSE CTE Research Project, focusing on former American football players (n = 166). The measures included whole-brain Fractional Anisotropy (FA), reflecting water diffusion directionality in white matter, and FreeWater-corrected FA (FAt) accounting for extracellular free water, using FSL Tract-Based Spatial Statistics (TBSS). We performed linear regressions on FA and FAt with age, age of first exposure to football, and estimates of cumulative head impact index (CHII) scores of frequency, linear acceleration, and rotational force controlling for age, body mass index, race, education, and APOE e4 allele presence as covariates.

Results
Both FA (p &lt; 0.00001) and FAt (p &lt; 0.00001) decreased as age increased. Moreover, FA (p &lt; 0.01) and FAt (p &lt; 0.01) were significantly lower with an earlier age of first exposure to football. Finally, FAt decreased as CHII linear acceleration (p &lt; 0.04) and rotational forces (p &lt; 0.02) increased.

Conclusion
Our study reveals age-related declines in both FA and FAt and highlights that the duration and intensity of exposure to RHI have an impact on white matter microstructure later in life. Overall, these results underscore the impact of prolonged exposure to RHI on white matter microstructure.
B - 56 Concussion Symptom Differences by Race/Ethnicity, Sex, and Age in Elementary-Age Children
Authors: Bunt Stephen C , Shurtz Logan , Didehbani Nyaz , Allen Tahnae , Hicks Cason L , Chowdhury Sebastian K , Hynan Linda L , Stokes Mathew , Miller Shane L , Silver Cheryl H , Cullum C M 
Published: September 2024

Abstract

Objective
The influence of race/ethnicity upon symptom presentation after concussion in young children is unclear, although adult studies suggest that white male participants may encounter fewer negative outcomes. This study’s objective was to compare symptoms in elementary-age children in the immediate post-concussion period by race/ethnicity, sex, and age.

Method
Children (N = 392) aged 5–12 years (m = 10.26, SD = 1.83) seen within 30 days of a concussion at a specialty concussion clinic. Participants completed the concussion symptom scale from the Sport Concussion Assessment Tool-5 (SCAT-5). The sample was 55.9% male with overall race/ethnicity 63.3% non-Hispanic White, 19.9% Hispanic/Latino, and 16.8% Black. Two-way (2x3) mixed-design ANOVA models examined number of endorsed SCAT-5 symptoms and total severity by racial/ethnic group, sex, and age. Participants were grouped by the following age ranges: 5–9 (N = 113), 10–11 (N = 143), and 12 years old (N = 134).

Results
Results showed no significant difference in total symptom count [F(2, 391) = 0.799, p = 0.460] nor symptom severity [F(2, 391) = 1.788, p = 0.169] across racial/ethnic groups. Females endorsed more symptoms [F(1, 391) = 20.383, p &lt; 0.001] and greater severity of symptoms [F(1, 391) = 16.826, p &lt; 0.001] than males. No significant symptom differences by age group were found.

Conclusion(s)
Comparison of concussion symptoms by race/ethnicity did not reveal differences for elementary-age children in this sample. As expected, females reported more symptoms than males. More research is needed with larger samples to examine sociodemographic aspects of concussion diagnosis, care, and recovery.
B - 59 Recreational Drug Use Predicts Self-Reported Attention, Memory, and Academic Problems
Authors: Rakichevich Emma , Rakichevich Emma , Bannout Zainab Y , Jacquin Kristine M 
Published: September 2024

Abstract

Objective
Our study examined the association between recreational substance use and neuropsychological impairments.

Method
Over 400 (N = 412) American adults (aged 18–75; M = 32.7, SD = 11.5) were recruited through Prolific to complete an online survey including the Drug Use Survey and Neuropsychological Impairment Scale. Participants reported being men (53.2%), women (42.7%), non-binary (2.2%), and other genders, and white (62.1%), African American/Black (17.0%), Asian/Asian American (8.0%), Hispanic/Latinx (6.8%), or other ethnicities (6.1%). We have no conflicts to report.

Results
Regression analyses showed that frequency of substance use significantly predicted self-reported inattention, F(11, 400) = 7.62, p &lt; 0.001, adj. R2 = 0.15. The best predictors of inattention were cannabis use, non-medical use of prescription psychostimulants, and inhalant use. Similarly, substance use predicted memory problems, F(11, 400) = 4.68, p &lt; 0.001, adj. R2 = 0.09. Strongest predictors of memory problems were cannabis, hallucinogen, and inhalant use. Likewise, cannabis use, inhalant use, and non-medical use of prescription psychostimulants significantly predicted academic problems, F(11, 400) = 3.89, p &lt; 0.001, adj. R2 = 0.07.

Conclusions
As hypothesized, our study found that substance use is a significant predictor of self-reported inattention, memory issues, and academic problems. Specifically, results suggest that cannabis users, non-medical users of prescription psychostimulants, and inhalant users experience more inattention and academic problems than non-users; these substance users and hallucinogen users experience more memory problems. The results of this study contribute to the growing body of literature highlighting the strong connection between recreational substance use and inattention, memory problems, and academic problems.
B - 76 Resilience and Executive Function: Protective Factors for Mental Health Professionals’ Eating Behaviors
Authors: Steinbaugh Ashlynn , Steinbaugh Ashlynn , Rousseau Alexandra , Rathke Laura , Adler Jennifer S , Kaswan Naomi , Hirst Rayna 
Published: September 2024

Abstract

Objectives
Eating disorders (EDs) affect 30 million individuals in the United States with serious health consequences, including fatality. Their impact on mental health professionals (MHPs) working with eating disorder (ED) populations remains understudied. This study aimed to examine the relationship between MHPs’ eating behaviors and potential protective factors.

Method
Professionals (N = 100) completed a survey of demographic information, ED symptoms, resilience, and executive functioning (EF) skills, and completed the Eating Disorder Examination Questionnaire (EDE-Q), the Connor-Davidson Resilience Scale (CD-RISC-10), and the Behavioral Rating Inventory of Executive Function - Adult Version (BRIEF-A).

Results
Nearly half of the participants (44%) indicated current work with ED populations and an average of 6.74 (SD = 9.76) years spent treating individuals with EDs. MHPs reported spending an average of 9% (SD = 16) of their current work-week with ED populations and endorsed ED work-specific stress as a contributor to their eating habits, with one third of MHPs endorsing sub-clinical ED behaviors. Resilience and EF appeared as significant protective factors against ED symptoms (ps &lt; 0.05). GEC, BRI, and MI separately accounted for significant amounts of variance in EDE-Q scores (R2 = 0.12; R2 = 0.08; R2 = 0.13, respectively). There were no significant interactions between time working with individuals with EDs and EF scores on EDE-Q scores (p = ns).

Conclusions
This study is the first to examine ED behaviors, EF, and resilience in MHPs, revealing that resilience and EF serve as protective factors. Such qualities appear critical in preventing the development or exacerbation of professionals’ mental health symptoms.
B - 78 Examining how Adverse Childhood Experiences and the Underlying Processes of Trait and State Impulsivity Influence Suicidal Behavior
Authors: Duran Julia K , Naylor-Tincknell Janett M , Rieske Robert 
Published: September 2024

Abstract

Objective
This study sought to better understand how ACEs, suicidal behavior, and impulsivity are interconnected by first examining the relationships between reported ACEs and levels of trait and state impulsivity as well as how ACEs and multiple dimensions of trait and state impulsivity influence suicidal behavior.

Method
311 participants (19–67 years old; 49.2% male; 40.2% Caucasian) were recruited through Amazon’s Mechanical Turk. Adverse Childhood Experiences and suicidal behaviors were assessed using the ACE-Q and SBQ-R. The short version UPPS-P scale was used to measure negative urgency, lack of premeditation, lack of perseverance, sensation seeking, and positive urgency whereas behavioral lab tasks were used to measure prepotent response inhibition, delay discounting, and distortions in elapsed time.

Results
Simple bivariate regressions revealed ACEs are a significant predictor of prepotent response inhibition and total S-UPPS-P scores as well as the specific subscales of negative urgency, positive urgency, and sensation seeking. Furthermore, a hierarchical regression found total ACE scores, poor time perception, and the tendency to act rashly while experiencing negative emotions (negative urgency) to be significant predictors of total suicidal behavior scores. Lastly, an ordinal logistic regression suggests a greater likelihood that individuals will go from suicidal ideation to planning, and from planning to attempting when they tend to act rashly while experiencing negative emotions, have less regard for consequences (lack of premeditation), and have experienced more ACEs.

Conclusion
By identifying the specific risk factors for suicidal behavior, we can recognize individuals at greater risk of attempting, as well as target and mitigate the effects of these behaviors through intervention.
B - 81 Teleneuropsychological Normative Data for the Spanish CERAD Wordlist for Puerto Rican Adults
Authors: Cintrón Ortiz Bianca P , Zambrana-Bonaparte Hjalmar 
Published: September 2024

Abstract

Objective
The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD) Wordlist is one of the most commonly used and sensitive tests to detect early cognitive decline (Seo et al., 2010). However, few studies have utilized it with the Puerto Rican population, and none have established normative data on its teleneuropsychological (TeleNP) use. Therefore, this study aims to establish normative data for the TeleNP version of the CERAD Wordlist among Puerto Ricans.

Method
124 cognitively healthy (MMSE: M = 28.9, SD = 1.4) Spanish-speaking Puerto Ricans (Female: 71.8%; Age M = 64.6, SD = 7.3; Education M = 15.9, SD = 3.5) completed an online version of the CERAD Wordlist via Zoom. The impact of age and education was investigated using analyses of variance (ANOVA) and Pearson correlations. Descriptive statistics were conducted to generate normative data stratified by statistically significant demographics. Concurrent validity was established between the delayed recall trials of the CERAD Wordlist and MMSE.

Results
Age and education significantly impacted CERAD Wordlist scores (p &lt; 0.01) across all Learning Trials and Delayed Recall. All effect sizes were large, except for moderate sizes in Trial 1 and Wordlist Recognition. Age was inversely correlated to scores, while education was positively correlated. Concurrent validity with TeleNP MMSE was 0.43 (p &lt; 0.001).

Conclusions
This study establishes normative data for Puerto Ricans using the TeleNP version of the CERAD Wordlist, which can improve diagnostic accuracy. Future research on the CERAD Wordlist via TeleNP should explore clinical validity and encompass a broader range of educational backgrounds.