bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-implantation and uterotonic properties of Mentha pulegium L. in female Sprague-Dawley rats
Authors: Sallah Lorraine , Coffie Peter N. , Babatunde Duduyemi M. , Danquah Cynthia Amaning , Baah Fred K. , Mante Priscilla K. , Owusu-Daaku Kofi O. 
Published: September 2024

Background: Some traditional herbs disrupt endocrine-endometrial synchrony, affecting embryo-endometrium communication during fertility. Hormonal imbalances cause non-receptive conditions, leading to anti-implantation or abortion. Historically, Mentha pulegium has served for contraceptive and abortive purposes. Its effects on the post-coital contraceptive and hormonal activities were evaluated.
Methods: Thirty-six Sprague-Dawley female rats were selected based on the presence of copulation plugs and received 200, 500, and 1000 mg/kg of Hydroethanolic leaf extract of Mentha pulegium L. (MPE) for seven days. Reproductive organ weights and serum estrogen and progesterone levels were measured. The resorption index, anti-implantation activity, and pre-implantation loss were also calculated using the number of implantation sites and resorptions in all treatments. Data were presented as mean±standard error mean (SEM), and significance was defined as p<0.05 using one-way ANOVA.
Results: Post-coital administration of MPE resulted in resorptive, pre-implantation loss, and anti-implantation activity. A dose of 200 mg/kg reduced the number of implantations and exhibited a high resorption index, percentage pre-implantation loss, and anti-implantation activity. A marked decline in serum progesterone levels and a significant reduction in serum estrogen and progesterone ratio was observed at 200 mg/kg MPE. A significant increase in uterine weight was observed in the 500 mg/kg treatment. Doses of 500 and 1000 mg/kg resulted in a significant reduction in anti-implantation activity.
Conclusions: The observed anti-implantation activity and pre-implantation loss suggest the abortifacient properties of MPE. However, its effects were seen to be dose-dependent.
Evalution of shear bond strength of brackets bonded using different hydrophobic and hydrophilic adhesives: An invitro study
Authors: Markand Megha Vilas , Patil Tushar , Misal Abhijit , Mahamuni Avinash , Gudadhe Rajshree , Sakhariya Samkit 
Published: September 2024

A review of the long history of orthodontic bonding adhesives shows that many evolutional developments have occurred from the first chemically-cured composite resins to the most recently introduced light-cured color-change adhesives. An ideal orthodontic adhesive should have adequate bond strength while maintaining unblemished enamel after debonding. Therefore, researchers have been working hard to achieve the best quality and gentlest materials for bonding orthodontic brackets.To evaluate the shear bond strength of brackets bonded using four different adhesives in both dry and in moist environment.A total of 80 orthodontically extracted premolars will be selected. They are divided into 4 equal groups of different adhesives which are further sub-divided into 2 group each (dry and in presence of moisture). All the selected teeth will be cleaned and store in saline until it use. All teeth will be mounted on acrylic block. The shear bond strength will be measured by Lloyd’s Universal testing machine. The obtained data will be statistically evaluated using SPSS22 for Windows using ANOVA test at statistical significance.: The shear bond strength of the four groups were tested with Instron universal testing machine; breaking load at which bond failure occurred was recorded and bond strength was calculated. Data obtained was compiled on MS Office Excel Sheet (2007, Microsoft Redmond Campus, Redmond. Washington, United States.)Data was subjected to statistical package for social sciences (SPSS v 21).Statistically significant difference seen between the hydrophobic and hydrophilic adhesives. In the present study we did Tukey’s post hoc test for pairwise comparison of different hydrophobic and hydrophilic adhesives. It show highly significant values. : The greatest bond strength values were achieved with TransbondXT in both dry and saliva contamination condition. These values were significantly greater than those achieved with Greengloo, RMGIC and Aqualine LC. The overall study conclude that TransbondXT was considered the feasible adhesive material for orthodontic bonding followed by Aqualine LC.
El rol de los trabajadores de la salud en el contexto de las politicas reparatorias por violaciones de derechos humanos
Authors: Balaña Sabrina , Kaski Federico , Reinoso Silvana , Rodríguez Javier , Rousseaux Fabiana , Serritella Juliana 
Published: September 2024

En el presente trabajo buscamos dar cuenta de la experiencia y las distintas estrategias queenimos desarrollando en el Centro de Asistencia a Víctimas de Violaciones de Derechos Humanos, “Dr. Fernando Ulloa”, dependiente de la Secretaría de Derechos Humanos de la Nación, en relación con la forma de implementación de las políticas reparatorias en materia de derechos, llevadas adelante por el Estado Nacional, bajo las premisas de Memoria, Verdad y Justicia.
Desarrollaremos las distintas estrategias implementadas, como la Red de Derivación y Asistencia a víctimas, y el Plan Nacional de Acompañamiento y Asistencia a víctimas testigos y querellantes en los juicios por delitos de lesa humanidad. Asimismo, describiremos el marco legal vigente en materia reparatoria, como el armado de las Juntas Médicas en este contexto.
Por último, intentaremos promover la reflexión en torno a la injerencia de las prácticas de los trabajadores de la salud en el proceso de lareparación integral de las víctimas de violaciones de Derechos Humanos, partiendo de la noción de su rol en tanto agentes del Estado.
Effective factors on Migration to Kerman City and Immigrants’ Problems Using Analytical Hierarchy Process Model and Technique for Order of Preference by Similarity to Ideal Solution
Authors: Sanjari Paymaneh , Hashemi Majid , Dehesh Tania , Tabatabaei Sayed Vahid Ahmadi , Faraji Maryam 
Published: September 2024

Introduction: Marginal immigrants cause many problems in economic, social and cultural, physical ,and environmental aspects of cities. This study aims to investigate the factors affecting migration to Kerman city and the problems of marginalized immigrants using the analytical hierarchy process (AHP) and technique for order of preference by similarity to ideal solution (TOPSIS) models.
Methods: This cross-sectional study was conducted in 2022, with a sample size of 147 households selected from Kerman suburban region. The data were collected by a standardized questionnaire measuring effective factors on the migration and the checklist of the immigrant problems.
Results: The most important immigration factors were economic, social, geographical, political, educational and religious-cultural factors, respectively. Among 37 components studied, transferring the job of the family man as the family head, being on the main land, air and rail ways, having a special position at the international level, burying the family’s dead members in the desired city, and the education of the wife or one of the children of the family were the most important components.
According to the results, more than 90% did not have access to public baths, sports facilities, government centers, private institutions, and parks, and recreational spaces.
Conclusion: According to AHP model, economic factors ,and then social factors, were the most important reasons for migrating to the suburbs of Kerman. Therefore, it is suggested to create stable and long-term job opportunities , improve employment and business environment in the cities, and develop infrastructure to control migration to the city capitals.
Flat Foot based on Clarke's Angle Method and Overweight among Medical Students of Universitas Airlangga
Authors: Putri Nelsya Safira Aulia , Arfianti Lydia , Desnantyo Andre Triadi , Wardhani Indrayuni Lukitra 
Published: September 2024

Highlights:

Being overweight can be one of the causes of flat foot.
A person with flat feet may experience pain in the medial malleolus area and discomfort when tiptoeing.

Abstract
Introduction: A flat foot is an arch deformity, and being overweight is one of the risk factors. It can cause problems such as fatigue, pain in the ankle and back, foot pain (especially during long walks or sports), and disturbances in balance and walking patterns. This study aimed to examine the relationship between flat feet (measured using Clarke's angle) and overweight students at the Faculty of Medicine, Universitas Airlangga.
Methods: This study used an observational analytic design with a cross-sectional method, gathering primary data directly from the research sample. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26.
Results: Of the 56 samples meeting inclusion criteria, most cases of flat foot occurred in males. A total of 36 research subjects were overweight or obese, evenly split between females and males. Among the 112 samples, 19 had flat feet, and 93 did not. Chi-square test analysis indicated a highly significant p-value (0.001, p < 0.05), suggesting a significant relationship between flat feet and overweight.
Conclusion: There was a significant relationship between flat feet (measured using Clarke's angle) and overweight. The majority of subjects in this study were overweight based on body mass index (BMI), and most had a non-flat foot arch type. All cases of flat foot were found in subjects with overweight BMI.
Outcomes of Obese Patients Undergoing Primary Total Knee Arthroplasty
Authors: Uvodich Mason E. , Dugdale Evan M. , Pagnano Mark W. , Berry Daniel J. , Abdel Matthew P. , Bedard Nicholas A. 
Published: September 2024

Background:
The rates of obesity among patients undergoing total knee arthroplasty (TKA) have substantially increased. In addition, obesity is a well-established risk factor for complications after TKA. The purpose of this study was to analyze trends in body mass index (BMI) and complication risk among obese patients undergoing primary TKA treated at a single institution over 3 decades.

Methods:
Utilizing an institutional total joint registry, 13,919 primary TKAs performed to treat osteoarthritis between 1990 and 2019 were identified. Patients were stratified by BMI according to the World Health Organization (WHO) classification into 3 groups: non-obese (BMI, <30 kg/m2), WHO Class-I and II obese (BMI, 30 to 39.9 kg/m2), and WHO Class-III obese (BMI, ≥40 kg/m2). Trends in BMI and survivorship free from reoperation, revision, and periprosthetic joint infection (PJI) were analyzed over time while controlling for age, sex, and the Charlson Comorbidity Index.

Results:
Over the study period, there was a 90% increase in the prevalence of Class-II obesity (13% to 25%) and a 300% increase in Class-III obesity (3% to 12%). Analysis of the entire cohort demonstrated a decrease in the 2-year risk of any reoperation, any revision, and PJI (p < 0.05 for all) with time. The risk decreased significantly over time for non-obese patients for any reoperation (p = 0.029) and any revision (p = 0.004) and for Class-III obese patients for any reoperation (p = 0.038) and any revision (p = 0.012), but it remained stable for Class-I and II obese patients. The risk of PJI decreased from 1990 to 2019 for non-obese patients (p = 0.005), but there were no significant changes in PJI risk for any obesity group.

Conclusions:
Despite increasing rates of obesity among our patients who underwent TKA, we observed decreasing risks of reoperation, revision, and PJI over time. The risks of reoperation and revision declined among non-obese patients, remained stable for Class-I and II obese patients, and declined for Class-III obese patients. The PJI risk declined for non-obese patients over the study period, but no such decline occurred for any category of obesity. Despite the decreasing risks of reoperation and revision, further work is needed to improve PJI risk in obese patients.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
WITHDRAWN: A fairer way to compare researchers at any career stage and in any discipline using open-access citation data
Authors: Bradshaw Corey , Chalker Justin , Crabtree Stefani , Eijkelkamp Bart , Long John , Smith Justine , Trinajstic Kate , Weisbecker Vera 
Published: September 2024

Abstract

The pursuit of simple, yet fair, unbiased, and objective measures of researcher performance has occupied bibliometricians and the research community as a whole for decades. However, despite the diversity of available metrics, most are either complex to calculate or not readily applied in the most common assessment exercises (e.g., grant assessment, job applications). The ubiquity of metrics like the h-index (h papers with at least h citations) and its time-corrected variant, the m-quotient (h-index ÷ number of years publishing) therefore reflect the ease of use rather than their capacity to differentiate researchers fairly among disciplines, career stage, or gender. We address this problem here by defining an easily calculated index based on publicly available citation data (Google Scholar) that corrects for most biases and allows assessors to compare researchers at any stage of their career and from any discipline on the same scale. Our ε′-index violates fewer statistical assumptions relative to other metrics when comparing groups of researchers, and can be easily modified to remove inherent gender biases in citation data. We demonstrate the utility of the ε′-index using a sample of 480 researchers with Google Scholar profiles, stratified evenly into eight disciplines (archaeology, chemistry, ecology, evolution and development, geology, microbiology, ophthalmology, palaeontogy), three career stages (early, mid-, late-career), and two genders. We advocate the use of the ε′-index whenever assessors must compare research performance among researchers of different backgrounds, but emphasize that no single index should be used exclusively to rank researcher capability.
Hospital in-reach family-centred social prescribing pilot for children with neurodisability: mixed methods evaluation with social return on investment analysis
Authors: Gordon Laura , Hastry Megan , Bate Angela , Gordon Katie , Greaves Emily , Dimitriadou Simoni , Rapley Tim , Basu Anna Purna 
Published: September 2024

Abstract

Background Social prescribing (SP) link workers (LWs) support individuals to engage with community resources, co-creating achievable goals. Most schemes are community-based, targetting adults. Vulnerable populations including hospitalized children with neurodisability and their families, could also benefit from SP.Aims To pilot a hospital-initiated SP service for children with neurodisability and their families; to explore its feasibility, acceptability and undertake social return on investment (SROI) analysis.Methods Mixed-methods cohort study with SROI analysis. We recruited children aged < 16y with neurodisability, identified during inpatient stays, their parents/carers and siblings. Participants received LW support for 6 months, extending beyond hospital discharge. Pre- and post-intervention pilot data covered profile of needs (Support Star), quality of life (EQ5D/CHU-9D), wellbeing (WEMWBS/CORS) and financial strain. We undertook 22 qualitative observations of family/LW interactions and 39 in-depth interviews with families, LWs, and healthcare professionals (HCPs). Together these data were analysed within a SROI to establish the costs and social value generated.Results Of 48 families supported by the service, 25 were recruited to the evaluation (26 children, aged 10m-15y; 4 siblings; 36 parents). Baseline quality of life and wellbeing indices averaged below population norms. LWs were highly effective at supporting families (only 6/151 goals unmet). Unmet need decreased by 6 months (Support Star, p < 0.001).Trial registration ISRCTN 42100
Prospective association between breakfast consumption frequency and BMI z-score among European school-aged children. The Feel4Diabetes Study.
Authors: Manios Yannis , Kostarellou Panayiota , Anastasiou Costas , Karaglani Evangelia , Iotova Violeta , Usheva Natalya , Tankova Tsvetalina , Rurik Imre , Diakoumopoulou Evanthia , Giménez-Legarre Natalia , Moreno Luis , Lindstrom Jaana , Wikström Katja , Cardon Greet , Makrilakis Konstantinos 
Published: September 2024

Abstract

Background
The long-term effects of breakfast on childhood z-BMI remain inconclusive.
Objective
To prospectively assess the impact of stable and altered breakfast consumption habits on z-BMI change over two years, in school-aged children across six European countries.
Methods
Data of 6,528 children (8.2 ± 1.0 years, 48.9% male) from the Feel4Diabetes study were used. Children's lifestyle behaviors, including breakfast frequency, were assessed through parent-reported questionnaires. Weight and height were objectively measured and converted to z-BMI. Participants were categorized into trajectories combining breakfast consumption habit (i.e. regular consumption, irregular consumption or omission) at baseline and follow up. Logistic regression analyzed the prospective association between breakfast trajectories and z-BMI increase, with adjustment for demographic and lifestyle variables.
Results
A statistically signidficant effect of breakfast trajectories was observed in z-BMI, both at baseline and follow up. Stable skippers was the only trajectory that showed a significant increase in BMI z-score from baseline to follow up (0.891 ± 1.058 vs. 1.034 ± 1.072 respectively, p < 0.05). BMI z-score at follow up of regular eaters (0.615 ± 0.967) was significantly lower, compared to both irregular eaters (1.229 ± 0.890) and stable skippers (both p < 0.05).Stable regular consumption and transition from omission to regular consumption were independently associated with significantly lower risk of z-BMI gain, compared to stable omission [OR,95%CI: 0.55 (0.31,0.97), p = 0.039 and 0.43 (0.21, 0.88), p = 0.021 respectively].
Conclusion
Stable regular breakfast consumption or transition from omission to regular consumption seem to contribute to superior weight regulation in children and to independently protect against z-BMI gain, compared to stable omission. Further studies are warranted to extend the evidence on the breakfast habit-BMI association among children.
Genetic basis of alkaloid divergence in the Solanaceae
Authors: Pérez Pablo , Perez-Mesa Pablo , Pardo Ronald A. , Alseekh Saleh , Rojas-Contreras Sofía , Sierra Gina P. , García D. Estevan , Orejuela Andrés , Fernie Alisdair R. , Lopez-Kleine Liliana , Roda Federico 
Published: September 2024

Abstract

Plant lineages produce distinctive alkaloids, suggesting the existence of evolutionary mechanisms preventing the simultaneous metabolism of multiple alkaloid types in the same species. Tribes in the Solanaceae family produce either tropane alkaloids (TAs) or steroidal glycoalkaloids (SGAs). We integrated genomic, transcriptomic, and metabolomic variation across tens of species representing most Solanaceae tribes to evaluate three possible genetic causes of this mutually exclusive distribution, namely (1) loss of biosynthetic genes, (2) genomic clustering, and (3) regulatory changes. We found that both pathways are produced by multiple phylogenetic clades, suggesting that the differential loss of the biosynthetic pathways across lineages could explain their patchy distributions in the phylogeny. However, TA and SGA genes show contrasting patterns of genomic presence and distribution: SGA genes are grouped in large and dynamic biosynthetic clusters but are present across most species whereas TA genes are sparsely distributed and almost exclusively present in TA-producing species genomes. Additionally, SGA and TA genes are preferentially expressed in species that produce SGAs and TAs respectively, suggesting that expression differences were crucial for the divergence of the two pathways. Our results highlight the asymmetric significance of gene loss, genomic clustering, and gene expression differences in the divergence of TAs and SGAs.
Ordered Networked Analysis of Multimodal Data in Healthcare Simulations: Dissecting Team Communication Tactics
Authors: Zhao Linxuan , Echeverria Vanessa , Tan Yuanru , Yan Lixiang , Li Xinyu , Alfredo Riordan , Dix Samantha , Jaggard Hollie , Wotherspoon Rosie , Osborne Abra , Winter Rebecca , Shaffer David Williamson , Gašević Dragan , Martinez-Maldonado Roberto 
Published: September 2024

Abstract

In highly immersive, team-based healthcare simulations, students must collaborate effectively to complete open-ended learning tasks. These often require students to move among multiple locations within the physical learning space, 1 requiring the development of effective communication tactics to manage complex team dynamics and multiple concurrent dialogue segments. Analysing such distributed team dialogue using only audio data poses significant challenges as it is hard to distinguish how teams temporarily break into smaller groups. This study investigates the integration of audio and spatial data to model embodied team communication tactics in highly-dynamic healthcare simulation scenarios. We employ ordered network analysis (ONA) to examine the order of communication behaviours across coded co-located dialogue segments of teams of nursing students. We also explore the potential of ONA to enhance teaching through a qualitative assessment of its usability with teachers. Results reveal that high-performing teams employ effective team tactics by prioritising primary tasks (i.e., deteriorating patients) and performing critical tasks timely and correctly, while low-performing teams struggle to develop prioritisation tactics (i.e., focus-ing on stable patients) and with team coordination. Interviews with teachers found high-level information in ONA networks interpretable but faced challenges with sequential details and contextualisation. This research offers insights into improving team-based learning and assessment in healthcare education.
Fiscal decentralization and sustainable development in Africa: an empirical investigation from inequality
Authors: Marcel DAMA DIE , Loudi NJOYA , Philémon VOTSOMA 
Published: September 2024

Abstract

There is no consensus among public economists as to which of the central and local governments should perform the redistributive function. While most authors recommend the centralisation of this function (Tiebout, 1956; Musgrave, 1959; Oates, 1972, Tanzi, 1995), some (Buchanan, 1950; Pauly, 1969; Perotti, 1992) have shown that its decentralisation would be equally if not more effective. This paper analyses the effect of fiscal decentralisation on inequality in Africa over the period 2005–2018. Using a sample of 17 African countries, we estimate a panel data model using the Ordinary Least Squares (OLS), Fixed Effects (FE) and Generalized Moment Method (GMM) in System. Our results show that fiscal decentralization reduces environmental and housing inequalities in Africa. These results remain robust to the use of MMG. We suggest the valorisation of local policies in governance policies in Africa.
Jel code: H23, H71.