bluuebunny/crossref_metadata_2025_split huggingface dataset:
EASI‐IMS an expedite and secure technique to screen for 25I‐NBOH in blotter papers
Authors: de Morais Damila Rodrigues , Barbosa Ingrid Lopes , Cunha Kelly Francisco , Tripodi Guilherme Lucas , Angolini Célio Fernando Figueiredo , Franco Marcos Fernando , de Aquino Elvis Medeiros , Eberlin Marcos Nogueira , Costa Jose Luiz 
Published: July 2017

AbstractThe increasing number of new psychoactive substances (NPS) and their quick worldwide spreading, often only slightly modified in the form of new derivatives and analogues, have brought the need for fast, wide‐ranging, and unequivocal identification methods in clinical and forensic investigations. Because it usually provides secure results, gas chromatography coupled to mass spectrometry (GC‐MS) has been routinely employed as the standard technique for the detection of NPS in blotter papers. For 25I‐NBOH (N‐(2‐hydroxybenzyl)‐2‐(4‐iodo‐2,5‐dimethoxyphenyl)ethan‐1‐aminium), however, GC‐MS analysis of an blotter paper extract leads to incorrect results. In this work, we investigated whether easy ambient sonic‐spray mass spectrometry imaging (EASI‐IMS), and ambient ionization MS method can be applied directly to the surface of the sample requiring therefore no extraction or sample preparations, would serve as an efficient, sensitive, and secure alternative for 25I‐NBOH screening.
1961–1990 high‐resolution monthly precipitation climatologies for Italy
Authors: Crespi A. , Brunetti M. , Lentini G. , Maugeri M. 
Published: July 2017

ABSTRACTHigh‐resolution monthly precipitation climatologies for Italy are presented. They are based on 1961–1990 precipitation normals obtained from a quality‐controlled dataset of 6134 stations covering the Italian territory and part of the Northern neighbouring regions. The climatologies are computed by means of two interpolation methods modelling the precipitation‐elevation relationship at a local level, more precisely a local weighted linear regression (LWLR) and a local regression kriging (RK) are performed. For both methods, local optimisations are also applied in order to improve model performance. Model results are compared with those provided by two other widely used interpolation methods which do not consider elevation in modelling precipitation distribution: ordinary kriging and inverse distance weighting. Even though all the four models produce quite reasonable results, LWLR and RK show the best agreement with the observed station normals and leave‐one‐out‐estimated mean absolute errors ranging from 5.1 mm (July) to 11 mm (November) for both models. Their better performances are even clearer when specific clusters of stations (e.g. high‐elevation sites) are considered. Even though LWLR and RK provide very similar results both at station and at grid point level, they show some peculiar features. In particular, LWLR is found to have a better extrapolation ability at high‐elevation sites when data density is high enough, while RK is more robust in performing extrapolation over areas with complex orography and scarce data coverage, where LWLR may provide unrealistic precipitation values. However, by means of prediction intervals, LWLR provides a more straightforward approach to quantify the model uncertainty at any point of the study domain, which helps to identify the areas mainly affected by model instability. LWLR and RK high‐resolution climatologies exhibit a very heterogeneous and seasonal‐dependent precipitation distribution throughout the domain and allow to identify the main climatic zones of Italy.
Development and validation of a subcritical 1,1,1,2‐tetrafluoroethane extraction technique: Gas chromatography–mass spectrometry method for the simultaneous determination of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, and polybrominated biphenyl ethers in aquatic products
Authors: Xu Feiyue , Feng Xiaomei , Shi Nianrong , Pan Jiangbo , Zhan Huashu , Han Yuqian 
Published: July 2017

AbstractA simple, rapid, and green method was developed for the simultaneous analysis of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, and polybrominated biphenyl ethers in aquatic products using subcritical 1,1,1,2‐tetrafluoroethane extraction coupled with gas chromatography and mass spectrometry. Effects of the extraction temperature, pressure, and cosolvent volume on the extraction efficiency were investigated by extracting spiked oyster samples. The results show that the maximum extraction efficiency was obtained at 40°C, 12 MPa, and a cosolvent (dichloromethane) volume of 5.0 mL. Under these conditions, the calibration curves had good linearity with square of the correlation larger than 0.998 in the concentration range of 5–800 ng/mL; limit of detection and limit of quantitation were 0.16–2.83 and 0.55–9.43 ng/g, respectively. At spiked levels of 10, 30, and 50 ng/g, the average recoveries were 70.4–80.4% for polycyclic aromatic hydrocarbons, 74.0–83.6% for polychlorinated biphenyls, and 66.9–78.0% for polybrominated biphenyl ethers, with average relative standard deviations of less than 16.3%. The established method has no significant differences in recovery compared to traditional methods and is suitable for the analysis of real samples.
Surf zones regulate larval supply and zooplankton subsidies to nearshore communities
Authors: Morgan Steven G. , Shanks Alan L. , MacMahan Jamie , Reniers Ad J. H. M. , Griesemer Chris D. , Jarvis Marley , Fujimura Atsushi G. 
Published: July 2017

AbstractSurf zone hydrodynamics vary along shorelines potentially affecting the delivery of larvae and zooplankton subsidies to intertidal communities, and, hence, the intensity of postsettlement interactions, growth and reproduction of filter‐feeding foundation species and planktivorous fishes. We investigated the ability of zooplankton assemblages to enter the wide surf zone of the rip‐channeled, more dissipative beach at Sand City, California, and the narrow surf zone of the steep reflective beach at nearby Carmel River State Beach. Every day for a month, we surveyed zooplankton inside and outside the surf zone and concomitant larval settlement of the dominant invertebrate onshore at each site in this upwelling regime. At the more dissipative surf zone, all zooplankters were far more concentrated inside than outside the surf zone. Many taxa increased in the surf zone and the predominant invertebrate on beaches, Emerita analoga, settled abundantly when prevailing northwesterly winds relaxed and waves were small. At the reflective surf zone, concentrations of zooplankters of most taxa were far greater outside than inside the surf zone, and many taxa increased in the surf zone when waves were small. Twice as many taxa were positively correlated inside and outside the surf zone at the dissipative than the reflective surf zone, indicating that zooplankters were more freely exchanged although behavior also played a role. Thus, spatial and temporal variation in surf zone hydrodynamics may regulate subsidies of zooplankton food and larval recruits to nearshore communities with potential cascading effects on community dynamics and structure.
mcp, aer, cheB, and cheV contribute to the regulation of Vibrio alginolyticus (ND‐01) adhesion under gradients of environmental factors
Authors: Huang Lixing , Wang Lu , Lin Xiangzhi , Su Yongquan , Qin Yingxue , Kong Wendi , Zhao Lingmin , Xu Xiaojin , Yan Qingpi 
Published: July 2017

AbstractAdhesion is a key virulence factor of pathogens and can be affected by the environment. Our previously research with RNA‐seq indicated that mcp, aer, cheB, and cheV might play roles in the regulation of adhesion in Vibrio alginolyticus (ND‐01). In order to determine whether and how environmental factors affect adhesion through these genes, gene silencing was performed followed by quantitative real‐time PCR (qRT‐PCR), RNAi, transmission electron microscopy, and adhesion, capillary, and motility assays to verify how these genes influence adhesion. Silencing these genes led to deficiencies in adhesion, chemotaxis, flagellar assembly, and motility. The expression levels of cheA, cheW, and cheY, which are important genes closely related to the functions of mcp, aer, cheV, and cheB, were significantly downregulated in all of the RNAi groups. The expression of mcp, aer, cheV, and cheB under different gradients of temperature, pH, and salinity and after starvation for various durations was also detected, which showed that these genes were sensitive to certain environmental stresses, particularly pH and starvation. Our results indicated that mcp, aer, cheB, and cheV: (1) are necessary for ND‐01 adhesion; (2) play key roles in the bacterial chemotaxis pathway by controlling the expression of downstream genes; (3) might affect adhesion by impacting motility, though motility is not the only route through which adhesion is affected; and (4) contribute to the regulation of ND‐01 adhesion in natural environments with different temperatures, pH levels, and salinities as well as after various starvation periods.
Vascularized ulnar periosteal pedicled flap for forearm reconstruction: Anatomical study and a case report
Authors: Barrera‐Ochoa Sergi , Velez Roberto , Rodriguez‐Baeza Alfonso , De Bergua‐Domingo Josep Maria , Knörr Jorge , Soldado Francisco 
Published: July 2017

AbstractPurposeThrough an anatomical review, the aim of this study is to define the ulnar periosteal branches of the posterior interosseous vessels (PIV). In addition, we report the clinical utility of a vascularized ulnar periosteal pedicled flap (VUPPF), supplied by the investigated PIV, in a complex case of radial nonunion.MethodsTen upper limbs latex colored from fresh human cadavers were used. Branches of the PIV were dissected under 2.5× loupe magnification, noting the periosteal, muscular, and cutaneous branches arising distal to the interosseous recurrent artery. The VUPPF was measured in length (cm) and width (cm).ResultsThe PIV provided a mean 12.8 periosteal branches to the ulna distributed along the most distal 15 cm, with a mean distance between branches of 1 cm, allowing for the design of a VUPPF which measured a mean 12 cm in length and 1.7 cm in width. We used a VUPPF of 7.8 cm in length and 2 cm in width to treat extensive nonvascularized bone graft nonunion with a defect of 2 cm of the left radius in a 6‐year‐old girl, secondary to previous Ewing's Sarcoma reconstruction. Successfully consolidation was achieved 6‐months after surgery. The patient did not present postoperative complications. At 2‐years of follow‐up after surgery, active supination was 80° and pronation 0° (due an incomplete interosseous ossification); grip strength was 80% that of the opposite hand. The patient had resumed all her daily activities.ConclusionsVUPPF may be considered a valuable and reliable surgical option for forearm reconstruction in complex clinical scenarios.
Analysis of a fractional order eco‐epidemiological model with prey infection and type 2 functional response
Authors: Mondal Shuvojit , Lahiri Abhijit , Bairagi Nandadulal 
Published: July 2017

In this paper, we introduce fractional order into an ecoepidemiological model, where predator consumes disproportionately large number of infected preys following type 2 response function. We prove different mathematical results like existence, uniqueness, nonnegativity, and boundedness of the solutions of fractional order system. We also prove the local and global stability of different equilibrium points of the system. The results are illustrated with several examples.
Fast dose optimization for rotating shield brachytherapy
Authors: Cho Myung , Wu Xiaodong , Dadkhah Hossein , Yi Jirong , Flynn Ryan T. , Kim Yusung , Xu Weiyu 
Published: July 2017

PurposeTo provide a fast computational method, based on the proximal graph solver (POGS) – A convex optimization solver using the alternating direction method of multipliers (ADMM), for calculating an optimal treatment plan in rotating shield brachytherapy (RSBT).RSBTtreatment planning has more degrees of freedom than conventional high‐dose‐rate brachytherapy due to the addition of emission direction, and this necessitates a fast optimization technique to enable clinical usage.MethodsThe multi‐helixRSBT(H‐RSBT) delivery technique was investigated for five representative cervical cancer patients. Treatment plans were generated for all patients using thePOGSmethod and the commercially available solverIBM ILOG CPLEX. The rectum, bladder, sigmoid colon, high‐risk clinical target volume (HR‐CTV), andHR‐CTVboundary were the structures included in our optimization, which applied an asymmetric dose‐volume optimization with smoothness control. Dose calculation resolution was 1 × 1 × 3 mm3for all cases. The H‐RSBTapplicator had 6 helices, with 33.3 mm of translation along the applicator per helical rotation and 1.7 mm spacing between dwell positions, yielding 17.5° emission angle spacing per 5 mm along the applicator.ResultsFor each patient,HR‐CTVD90,HR‐CTVD100, rectumD2cc, sigmoidD2cc, and bladderD2ccmatched within 1% forCPLEXandPOGSmethods. Also, similarEQD2 values betweenCPLEXandPOGSmethods were obtained.POGSwas around 18 times faster thanCPLEX. For all patients, total optimization times were 32.1–65.4 s forCPLEXand 2.1–3.9 s forPOGS.ConclusionsPOGSreduced treatment plan optimization time approximately 18 times forRSBTwith similarHR‐CTVD90, organ at risk (OAR)D2ccvalues, andEQD2 values compared toCPLEX, which is significant progress toward clinical translation ofRSBT.
Psychometric investigation of the specific phobia of vomiting inventory: A new factor model
Authors: Maack Danielle J. , Ebesutani Chad , Smitherman Todd A. 
Published: July 2017

AbstractWell‐validated, standardized measures are lacking for the assessment of emetophobia, the specific phobia of vomiting. The Specific Phobia of Vomiting Inventory (SPOVI) was recently developed and shows promise as a useful measure of emetophobia. The goal of the present study was to further examine and investigate the psychometric properties of the SPOVI in a large student sample (n = 1626), specifically focusing on its factor structure, measurement invariance across gender, and convergent/divergent validity. Confirmatory factor analysis results provide support for a one‐factor model of the SPOVI, in contrast to the previously proposed two‐factor model. Internal consistency of the SPOVI was good (α = 0.89) and measurement invariance across gender invariance was supported. The SPOVI also demonstrated good psychometric properties with respect to convergent and divergent validity. The present study's demonstration of the reliability and validity of the SPOVI suggests that the instrument may be a valuable tool for assessing emetophobia symptoms based on its one‐factor structure.
Fat‐based registration of breast dynamic contrast enhanced water images
Authors: Srinivasan Subashini , Hargreaves Brian A. , Daniel Bruce L. 
Published: July 2017

PurposeIn this study, a 3D fat‐based deformable registration algorithm was developed for registering dynamic contrast‐enhanced breast images.MethodsThe mutual information similarity measure with free‐form deformation motion correction in rapidly enhancing lesions can introduce motion. However, in Dixon‐based fat‐water separated acquisitions, the nonenhancing fat signal can directly be used to estimate deformable motion, which can be later used to deform the water images. Qualitative comparison of the fat‐based registration method to a water‐based registration method, and to the unregistered images, was performed by two experienced readers. Quantitative analysis of the registration was evaluated by estimating the mean‐squared signal difference on the fat images.ResultsUsing a scale of 0 (no motion) to 2 ( > 4 voxels of motion), the average image quality score of the fat‐based registered images was 0.5 ± 0.6, water‐based registration was 0.8 ± 0.8, and the unregistered dataset was 1.6 ± 0.6. The mean‐squared‐signal‐difference metric on the fat images was significantly lower for fat‐based registered images compared with both water‐based registered and unregistered images.ConclusionsFat‐based registration of breast dynamic contrast‐enhanced images is a promising technique for performing deformable motion correction of breast without introducing new motion. Magn Reson Med 79:2408–2414, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
Assessment of Reynolds stress components and turbulent pressure loss using 4D flow MRI with extended motion encoding
Authors: Haraldsson Henrik , Kefayati Sarah , Ahn Sinyeob , Dyverfeldt Petter , Lantz Jonas , Karlsson Matts , Laub Gerhard , Ebbers Tino , Saloner David 
Published: July 2017

PurposeTo measure the Reynolds stress tensor using 4D flow MRI, and to evaluate its contribution to computed pressure maps.MethodsA method to assess both velocity and Reynolds stress using 4D flow MRI is presented and evaluated. The Reynolds stress is compared by cross‐sectional integrals of the Reynolds stress invariants. Pressure maps are computed using the pressure Poisson equation—both including and neglecting the Reynolds stress.ResultGood agreement is seen for Reynolds stress between computational fluid dynamics, simulated MRI, and MRI experiment. The Reynolds stress can significantly influence the computed pressure loss for simulated (eg, –0.52% vs –15.34% error; P < 0.001) and experimental (eg, 306 ± 11 vs 203 ± 6 Pa; P < 0.001) data. A 54% greater pressure loss is seen at the highest experimental flow rate when accounting for Reynolds stress (P < 0.001).Conclusion4D flow MRI with extended motion‐encoding enables quantification of both the velocity and the Reynolds stress tensor. The additional information provided by this method improves the assessment of pressure gradients across a stenosis in the presence of turbulence. Unlike conventional methods, which are only valid if the flow is laminar, the proposed method is valid for both laminar and disturbed flow, a common presentation in diseased vessels. Magn Reson Med 79:1962–1971, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
Long‐term outcomes and risks factors for failure of intradetrusor onabotulinumtoxin A injections for the treatment of refractory neurogenic detrusor overactivity
Authors: Joussain Charles , Popoff Mélanie , Phé Véronique , Even Alexia , Bosset Pierre‐Olivier , Pottier Sandra , Falcou Laetitia , Levy Jonathan , Vaugier Isabelle , Chartier Kastler Emmanuel , Schurch Brigitte , Denys Pierre 
Published: July 2017

AimsAims of this study were to assess the long‐term outcomes of Intradetrusor injection of OnabotulinumtoxinA (Botox® injection) associated with clean intermittent‐catheterization (CIC) for the treatment of neurogenic detrusor overactivity (NDO) and to identify risk factors for failure.MethodsNeurological patients with NDO using CIC who had received Botox® injections between January 2001 and September 2013 were included. Clinical, urodynamic and radiological data were recorded. Primary endpoint was failure and withdrawal rates after 3, 5, and 7 years of management. Survival curves of withdrawals and failures of treatment were calculated with a 95‐confidence interval using the Kaplan‐Meier method. Risk factors for failure were determined with univariate analysis and multivariate analysis using Cox model.ResultsOverall, 292 patients, mean age of 40 ± 13, 6 years, were included. Overall, 219 patients (80.6%; IC95% [76.3‐85.4%]) were still treated with Botox® injections after 3 years, 128 (71.1%; IC95% [65.7%, 76.9%]) after 5 years, and 58 (60.8%, IC95% [54.0%, 68.4%]) after 7 years. Failure rate was 12.6% (IC95% [8.6‐16.5%]) after 3 years, 22.2% (IC95% [16.6‐27.3%]) after 5 years, and 28.9% (IC95% [21.9%; 35.3%]) after 7 years of follow‐up. Withdrawal rate after 7 years of follow‐up was 11.3% (n = 33/292). Severe NDO at baseline appears to be a significant risk factor for failure.ConclusionThis study confirms long‐term efficacy and tolerance of Botox® injection in patients with NDO using CIC. Long‐term failure and withdrawal rates remain low but significant, and need to be managed.
Effects of vesical and perfusion pressure on perfusate flow, and flow on vesical pressure, in the isolated perfused working pig bladder reveal a potential mechanism for the regulation of detrusor compliance
Authors: Vince Randy , Tracey Andrew , Deebel Nicholas A. , Barbee Robert W. , Speich John E. , Klausner Adam P. , Ratz Paul H. 
Published: July 2017

AimsAlthough there is evidence that deficits in bladder blood flow negatively impact bladder function, the effects of vesical, and perfusion pressures on bladder perfusion (perfusate flow), and of perfusate flow on vesical pressure, remain poorly understood. The present study used the isolated perfused working pig bladder model to examine the relationships between blood flow, and vesical and perfusion pressures.MethodsVesical arteries of pig bladders obtained from a local slaughterhouse were cannulated and perfused with Krebs‐Henseleit solution at different pressures, and with carbachol to cause bladder contraction. The urethra of each bladder was cannulated to permit filling (10 mL/min), isovolumetric contraction and emptying. A ureter was cannulated with a pressure sensor to monitor vesical pressure.ResultsWhen at rest (50 mL vesical volume), bladder vesical pressure was 8.06 ± 1.5 mmHg and perfusate flow driven by a pressure gradient of 105 mmHg was 22.5 ± 2 mL/min (58.9 ± 7.8 mL/min‐100 g). During filling, vesical pressure increased and flow decreased, but not necessarily in‐parallel. Perfusate flow decreased transiently during isovolumetric contraction, and flow increased during emptying. A reduction in perfusion pressure from ∼105 to ∼40 mmHg reduced flow from ∼70 to ∼20 mL/min‐100g, and reduced flow correlated with reduced vesical pressure.ConclusionPerfusate flow is dependent on bladder perfusion pressure, and not necessarily reciprocally dependent on vesical pressure. Vesical pressure is highly sensitive to the level of perfusate flow, which supports the hypothesis that vesical pressure is dependent on the level of detrusor smooth muscle contractile activity (tone), and that compliance is dependent on bladder perfusion.
Relationship between work–family balance and job satisfaction among employees in China: A moderated mediation model
Authors: Yu Yue , Wang Yuchen , Zhang Jianxin 
Published: July 2017

AbstractPrevious studies have revealed the association between work–family balance and job satisfaction. The present research further explored the underlying mechanism of this association and aimed to provide a moderated mediation model to explain if personality traits moderate the relationship between work–family balance and job satisfaction through work engagement. A cross‐sectional study was conducted in which 263 employees from a petrochemical enterprise in China completed self‐report questionnaires including the Work–Family Balance Scale, the Utrecht Work Engagement Scale, the Big Five Inventory‐10, and the Job Satisfaction Scale. Hierarchical regression analysis and structural equation modeling showed that work engagement partially mediated the relationship between work–family balance and job satisfaction, and the indirect effect was further moderated only by extraversion. Therefore, an integrative moderated mediation model was proposed wherein work–family balance boosts job satisfaction by first enhancing employees’ work engagement, while the indirect effect was in turn moderated by extraversion. The results suggest that interventions for improving job satisfaction may be enhanced by targeting work engagement, especially for employees with higher extraversion.
Dark personality profiles: Estimating the cluster structure of the Dark Triad
Authors: Garcia Danilo , MacDonald Shane 
Published: July 2017

AbstractWe estimated the number of possible dark personality profiles in a large population (N = 18,088) using a subtractive clustering method, which suggested three cluster or dark personality profiles: high malevolent, intermediate malevolent, and low malevolent or benevolent. While the three profiles differed significantly in each dark trait, there was a considerably large cluster overlap.