bluuebunny/crossref_metadata_2025_split huggingface dataset:
Valoración del proceso de enseñanza-aprendizaje en el Trabajo Fin de Grado
Authors: Freire Esparís Pilar , Díaz Vázquez Rosario , Martínez Roget Fidel , Maside Sanfiz José Manuel , Del Rio Araujo María Luisa , Vázquez Rozas Emilia 
Published: October 2017

<p>La Facultad de Ciencias Económicas y Empresariales de la USC está entre las pioneras en la implantación del Trabajo Fin de Grado en la universidad española. En este artículo analizamos la valoración de los agentes implicados (alumnado y profesorado tutor). El trabajo se estructura en cinco ejes clave del proceso de enseñanza-aprendizaje: los elementos de apoyo (tutor, información y actividades formativas), el procedimiento de asignación de temas y tutores, las competencias desarrolladas, la dedicación requerida y el procedimiento de evaluación. Utilizamos datos procedentes de una encuesta realizada a 115 alumnos/as y 56 tutores/as, durante los cursos 2011-2012 y 2012-2013, en los Grados de Economía y ADE. Los resultados indican que el TFG se percibe como una materia con una metodología adecuada para lograr las competencias planteadas y en la que el 82,6% de los estudiantes no considera necesarias actividades formativas complementarias. Los criterios de evaluación utilizados son adecuados según la opinión aportada por el 78,6% del profesorado y el 44,3% del alumnado (el 55,7% restante introduciría variaciones muy poco significativas). Las valoraciones sobre el sistema de asignación de temas y tutores son menos robustas, presentando una fuerte dispersión. El tutor tiene un papel protagonista como transmisor de información. Es él quien demanda información por otras vías, que para el alumnado pueden considerarse subsidiarias. En conclusión, los resultados permiten describir al TFG como una materia con una metodología adecuada para adquirir las competencias planteadas, pero que exige un esfuerzo elevado -y escasamente reconocido- a todos los agentes que participan en ella.</p>
Contributions of foreign, domestic and natural emissions to US ozone estimated using the path-integral method in CAMx nested within GEOS-Chem
Authors: Dunker Alan M. , Koo Bonyoung , Yarwood Greg 
Published: October 2017

Abstract. The Goddard Earth Observing System global chemical transport (GEOS-Chem) model was used at 2°  ×  2.5° resolution to simulate ozone formation for a base case representing year 2010 and a natural background case without worldwide anthropogenic emissions. These simulations provided boundary concentrations for base and natural background simulations with the Comprehensive Air Quality Model with Extensions (CAMx) on a North American domain (one-way nested) at 12 km  ×  12 km resolution over March–September 2010. The predicted maximum daily average 8 h (MDA8) background ozone for the US is largest in the mountainous areas of Colorado, New Mexico, Arizona, and California. The background MDA8 ozone in some of these locations exceeds 60 ppb, when averaged over the 10 days with the largest base-case ozone (T10base average). The background ozone generally becomes both a larger fraction of the base-case ozone in the western US and a smaller fraction in the eastern US when proceeding from spring to summer to the T10base average. The ozone difference between the base and background cases represents the increment to ozone from all anthropogenic sources. The path-integral method was applied to allocate this anthropogenic ozone increment to US anthropogenic emissions, Canadian/Mexican anthropogenic emissions, and the anthropogenic components of the lateral and top boundary concentrations (BCs). Using the T10base average MDA8 ozone, the relative importance of the sources is generally US emissions  >  anthropogenic lateral BCs  >  Canadian/Mexican emissions  ≫  anthropogenic top BCs. Specifically, for 10 US urban areas, the source contributions were 12–53 ppb for US emissions, 3–9 ppb for lateral BCs, 0.2–3 ppb for Canadian/Mexican emissions, and  ≤  0.1 ppb for top BCs. The contributions of the lateral BCs are largest for the higher-elevation US sites in the Intermountain West and along the western boundary of the domain. In Denver, for example, the lateral BCs contribute 44 % to the T10base anthropogenic increment. Averaging over the 10 days in the background case with the largest MDA8 ozone (T10bkgd), the contribution from US emissions is reduced to 3–13 ppb at the 10 urban sites, leading to a reduction in the anthropogenic ozone increment. The contribution of the Canadian/Mexican emissions remains about the same (0.3–2 ppb), and the contribution from the lateral BCs increases (5–10 ppb), especially at the lower-elevation urban sites. The net effect at the urban sites is that the relative importance of the anthropogenic lateral BCs is significantly greater for the T10bkgd average than the T10base average. This is also true for rural sites studied, where the anthropogenic lateral BC contribution becomes as large as 68 % of the anthropogenic increment for the T10bkgd average. In addition to the source apportionment, we also used surface and ozonesonde measurements to evaluate GEOS-Chem and CAMx performance.
Quantitative Detection of Horse Contamination in Cooked Meat Products by ELISA
Authors: Thienes Cortlandt P , Masiri Jongkit , Benoit Lora A , Barrios-Lopez Brianda , Samuel Santosh A , Cox David P , Dobritsa Anatoly P , Nadala Cesar , Samadpour Mansour 
Published: October 2017

Abstract
Concerns about the contamination of meat products with horse meat and new regulations for the declaration of meat adulterants have highlighted the need for a rapid test to detect horse meat adulteration. To address this need, Microbiologique, Inc., has developed a sandwich ELISA that can quantify the presence of horse meat down to 0.1% (w/w) in cooked pork, beef, chicken, goat, and lamb meats. This horse meat authentication ELISA has an analytical sensitivity of 0.000030 and 0.000046% (w/v) for cooked and autoclaved horse meat, respectively, and an analytical range of quantitation of 0.05–0.8% (w/v) in the absence of other meats. The assay is rapid and can be completed in 1 h and 10 min. Moreover, the assay is specific for cooked horse meat and does not demonstrate any cross-reactivity with xenogeneic cooked meat sources.
Paleointensity From Subaerial Basaltic Glasses From the Second Hawaii Scientific Drilling Project (HSDP2) Core and Implications for Possible Bias in Data From Lava Flow Interiors
Authors: Cai S. , Tauxe L. , Cromwell G. 
Published: October 2017

AbstractIn this study, we collected samples from subaerial basaltic glassy margins from the second Hawaii Scientific Drilling Project (HSDP2) core. We employed the rigorous “IZZI” method during the paleointensity experiment combined with the stringent “CCRIT” criteria for data selection to obtain 21 robust paleointensity estimates recorded by glassy margins from 20 lava flows. We compared our new results to published paleointensities from the interiors of the lava flows from HSDP2 and found that our data are systematically lower than those from the interiors of the same lava flows. The reasons for the discrepancy in intensity are still unclear, but one possibility that could not be absolutely excluded is the effect of cooling rate on the more slowly cooled lava flow interiors. Although our new data from the glassy margins are lower than those from the lava flow interiors, they are still overall higher than the expected field of the study site calculated from a geocentric axial dipole model with an ancient average field of 42 ZAm2, either because of a long‐term local anomaly of the field in Hawaii or an insufficient age distribution of our new data (e.g., missing the time period with low field intensities).
Biogeochemical Impact of Snow Cover and Cyclonic Intrusions on the Winter Weddell Sea Ice Pack
Authors: Tison J.‐L. , Schwegmann S. , Dieckmann G. , Rintala J.‐M. , Meyer H. , Moreau S. , Vancoppenolle M. , Nomura D. , Engberg S. , Blomster L. J. , Hendricks S. , Uhlig C. , Luhtanen A.‐M. , de Jong J. , Janssens J. , Carnat G. , Zhou J. , Delille B. 
Published: October 2017

AbstractSea ice is a dynamic biogeochemical reactor and a double interface actively interacting with both the atmosphere and the ocean. However, proper understanding of its annual impact on exchanges, and therefore potentially on the climate, notably suffer from the paucity of autumnal and winter data sets. Here we present the results of physical and biogeochemical investigations on winter Antarctic pack ice in the Weddell Sea (R. V. Polarstern AWECS cruise, June–August 2013) which are compared with those from two similar studies conducted in the area in 1986 and 1992. The winter 2013 was characterized by a warm sea ice cover due to the combined effects of deep snow and frequent warm cyclones events penetrating southward from the open Southern Ocean. These conditions were favorable to high ice permeability and cyclic events of brine movements within the sea ice cover (brine tubes), favoring relatively high chlorophyll‐a (Chl‐a) concentrations. We discuss the timing of this algal activity showing that arguments can be presented in favor of continued activity during the winter due to the specific physical conditions. Large‐scale sea ice model simulations also suggest a context of increasingly deep snow, warm ice, and large brine fractions across the three observational years, despite the fact that the model is forced with a snowfall climatology. This lends support to the claim that more severe Antarctic sea ice conditions, characterized by a longer ice season, thicker, and more concentrated ice are sufficient to increase the snow depth and, somehow counterintuitively, to warm the ice.
Novel Ω‐Shaped Core–Shell Photodetector with High Ultraviolet Selectivity and Enhanced Responsivity
Authors: Hu Mingxiang , Teng Feng , Chen Hongyu , Jiang Mingming , Gu Yuzhu , Lu Hongliang , Hu Linfeng , Fang Xiaosheng 
Published: October 2017

AbstractThe design of nanostructure plays an important role in performance enhancement of low‐dimensional optoelectronic devices. Herein, a novel photodetector (PD) based on electrospun SnO2 nanofibers with Ω‐shaped ZnO shell (SnO2@ZnO) is fabricated. With 87.4% transmittance at 550 nm, SnO2@ZnO PD exhibits a high photo‐to‐dark current ratio up to 104 at around 280 nm. Owing to the additional Ω‐shaped ZnO shell, SnO2@ZnO PD possesses a responsivity of nearly 100 A W−1 under 5 V bias and the illumination of 250 nm light, which is 30‐time enhancement of pristine SnO2 PD. The enhancement is mainly attributed to type‐II energy band structure. Furthermore, by changing the direction of incident light, SnO2@ZnO PD has a high UV selectivity with an UV–vis rejection ratio (R250 nm/R400 nm) as much as 2.0 × 103 at 5 V bias under back illumination, which is fourfold higher than that under face illumination. The UV selectivity improvement may be attributed to light confinement in the Ω‐shaped structure. With both theoretical simulations and experimental comparisons, it is demonstrated that the unique compact Ω‐shaped nanostructure does contribute to photon trapping and gaining process, especially in back‐illumination configuration. The approach can be easily extended to other materials, preparing novel building blocks for optoelectronic devices.
Scaffold‐Based microRNA Therapies in Regenerative Medicine and Cancer
Authors: Curtin Caroline M. , Castaño Irene Mencía , O'Brien Fergal J. 
Published: October 2017

AbstractmicroRNA‐based therapies are an advantageous strategy with applications in both regenerative medicine (RM) and cancer treatments. microRNAs (miRNAs) are an evolutionary conserved class of small RNA molecules that modulate up to one third of the human nonprotein coding genome. Thus, synthetic miRNA activators and inhibitors hold immense potential to finely balance gene expression and reestablish tissue health. Ongoing industry‐sponsored clinical trials inspire a new miRNA therapeutics era, but progress largely relies on the development of safe and efficient delivery systems. The emerging application of biomaterial scaffolds for this purpose offers spatiotemporal control and circumvents biological and mechanical barriers that impede successful miRNA delivery. The nascent research in scaffold‐mediated miRNA therapies translates know‐how learnt from studies in antitumoral and genetic disorders as well as work on plasmid (p)DNA/siRNA delivery to expand the miRNA therapies arena. In this progress report, the state of the art methods of regulating miRNAs are reviewed. Relevant miRNA delivery vectors and scaffold systems applied to‐date for RM and cancer treatment applications are discussed, as well as the challenges involved in their design. Overall, this progress report demonstrates the opportunity that exists for the application of miRNA‐activated scaffolds in the future of RM and cancer treatments.
In Situ Coupling Strategy for the Preparation of FeCo Alloys and Co4N Hybrid for Highly Efficient Oxygen Evolution
Authors: Zhu Xiang , Jin Tian , Tian Chengcheng , Lu Chenbao , Liu Xiaoming , Zeng Min , Zhuang Xiaodong , Yang Shize , He Lin , Liu Honglai , Dai Sheng 
Published: October 2017

AbstractAn in situ coupling approach is developed to create a new highly efficient and durable cobalt‐based electrocatalyst for the oxygen evolution reaction (OER). Using a novel cyclotetramerization, a task‐specific bimetallic phthalocyanine‐based nanoporous organic framework is successfully built as a precursor for the carbonization synthesis of a nonprecious OER electrocatalyst. The resultant material exhibits an excellent OER activity with a low overpotential of 280 mV at a current density of 10 mA cm−2 and high durability in an alkaline medium. This impressive result ranks among the best from known Co‐based OER catalysts under the same conditions. The simultaneous installation of multiple diverse cobalt‐based active sites, including FeCo alloys and Co4N nanoparticles, plays a critical role in achieving this promising OER performance. This innovative approach not only enables high‐performance OER activity to be achieved but simultaneously provides a means to control the surface features, thereby tuning the catalytic property of the material.
Early diagnosis of lymphoma utilising Doppler pulmonary artery flow imaging
Authors: Su Tonglin , Kritharides Leonard , Chow Vincent 
Published: October 2017

AbstractThis case report illustrates the importance of careful Doppler interrogation of pulmonary artery (PA) and pulmonary artery branches in a standard Echocardiographic examination, which can be easily missed or ignored when using portable hand‐held device as this is usually a focussed examination. A comprehensive echocardiogram with dedicated superior vena cava (SVC) and detailed Doppler analysis of the PA added crucial information in the early diagnosis and expedited the commencement of life‐saving therapy in a 38‐year‐old female patient with lymphoma.
Do geographic differences or socioeconomic disparities affect survival in sinonasal squamous cell carcinoma?
Authors: Zhou Albert H. , Chung Sei Y. , Patel Varesh R. , Unsal Aykut A. , Hsueh Wayne D. , Baredes Soly , Eloy Jean Anderson 
Published: October 2017

BackgroundSquamous cell carcinoma (SCC) is the most common malignancy in the sinonasal tract. We present the first population‐based analysis that examines geographic differences in demographic and clinical characteristics, socioeconomic factors, treatment modality, and disease‐specific survival (DSS) of this entity.MethodsAll cases of sinonasal squamous cell carcinoma (SNSCC) were queried using the U.S. Surveillance, Epidemiology, and End Results (SEER) registry from 1973 to 2013. Patients were stratified by geographic location and characteristics such as demographics (age, gender, race, metropolitan/nonmetropolitan status, and income), stage at diagnosis, and treatment modality. Survival data were generated using Kaplan‐Meier regression analysis.ResultsIn total, 6094 patients were identified; 15.3% were from the East, 16.3% from the Midwest, 19.3% from the South, and 49.1% from the West. Patients from the South were younger (p < 0.001). The South had the highest proportion of patients who were black (p < 0.001), lived in nonmetropolitan areas (p < 0.001), and presented with localized disease (p < 0.001). Southern patients also had the lowest median income (p < 0.05), and were least likely to be treated with both surgery and radiotherapy (p < 0.001). The South exhibited the lowest 20‐year DSS compared to all other regions (p < 0.001).ConclusionSNSCC patients from the South had the poorest long‐term DSS, despite being most likely to present with localized disease. The South had the highest proportion of patients who were black, resided in rural or urban towns, had the lowest median income, and did not receive standard combination therapy, compared to the East, Midwest, and West.
A Manganese Pre‐Catalyst: Mild Reduction of Amides, Ketones, Aldehydes, and Esters
Authors: Kelly Colin M. , McDonald Robert , Sydora Orson L. , Stradiotto Mark , Turculet Laura 
Published: October 2017

AbstractA new (N‐phosphinoamidinate)manganese complex is shown to be a useful pre‐catalyst for the hydrosilative reduction of carbonyl compounds, and in most cases at room temperature. The Mn‐catalyzed reduction of tertiary amides to tertiary amines, with a useful scope, is demonstrated for the first time by use of this catalyst, and is competitive with the most effective transition‐metal catalysts known for such transformations. Ketones, aldehydes, and esters were also successfully reduced under mild conditions by using this new Mn catalyst.
More than 50% or Less than 70% Chance: Pragmatic Implications of Single‐Bound Probability Estimates
Authors: Hohle Sigrid Møyner , Teigen Karl Halvor 
Published: October 2017

AbstractProbability estimates can be given as ranges or uncertainty intervals, where often only one of the interval bounds (lower or upper) is specified. For instance, a climate forecast can describe La Niña as having “more than 70% chance” or “less than 90% chance” of occurring. In three experiments, we studied how research participants perceived climate‐related forecasts expressed with lower‐bound (“over X% chance”) or upper‐bound (“under Y% chance”) probability statements. Results indicate that such single‐bound statements give pragmatic information in addition to the numeric probabilities they convey. First, the studies show that these statements are directional, leading the listeners' attention in opposite directions. “Over” statements guide attention towards the possible occurrence of the event and are explained by reasons for why it might happen, while “under” statements direct attention to its possible non‐occurrence and are more often explained by reasons for why the target event might not appear, corresponding to positive (it is possible) versus negative (it is uncertain) verbal probabilities. Second, boundaries were found to reveal the forecaster's beliefs and could be perceived as indicative of an increasing or a decreasing trend. Single‐bound probability estimates are therefore not neutral communications of probability level but might “leak” information about the speaker's expectations and about past and future developments of the forecast. Copyright © 2017 John Wiley & Sons, Ltd.
Simulation‐based evaluation of the linear‐mixed model in the presence of an increasing proportion of singletons
Authors: Bruyndonckx Robin , Hens Niel , Aerts Marc 
Published: October 2017

AbstractData in medical sciences often have a hierarchical structure with lower level units (e.g. children) nested in higher level units (e.g. departments). Several specific but frequently studied settings, mainly in longitudinal and family research, involve a large number of units that tend to be quite small, with units containing only one element referred to as singletons. Regardless of sparseness, hierarchical data should be analyzed with appropriate methodology such as, for example linear‐mixed models. Using a simulation study, based on the structure of a data example on Ceftriaxone consumption in hospitalized children, we assess the impact of an increasing proportion of singletons (0–95%), in data with a low, medium, or high intracluster correlation, on the stability of linear‐mixed models parameter estimates, confidence interval coverage and F test performance. Some techniques that are frequently used in the presence of singletons include ignoring clustering, dropping the singletons from the analysis and grouping the singletons into an artificial unit. We show that both the fixed and random effects estimates and their standard errors are stable in the presence of an increasing proportion of singletons. We demonstrate that ignoring clustering and dropping singletons should be avoided as they come with biased standard error estimates. Grouping the singletons into an artificial unit might be considered, although the linear‐mixed model performs better even when the proportion of singletons is high. We conclude that the linear‐mixed model is stable in the presence of singletons when both lower‐ and higher level sample sizes are fixed. In this setting, the use of remedial measures, such as ignoring clustering and grouping or removing singletons, should be dissuaded.
Brain lesions affecting gait recovery in stroke patients
Authors: Lee Kyoung Bo , Kim Joon Sung , Hong Bo Young , Sul Bomi , Song Seojin , Sung Won Jin , Hwang Byong Yong , Lim Seong Hoon 
Published: October 2017

AbstractObjectivesGait recovery is an important goal in stroke patients. Several studies have sought to uncover relationships between specific brain lesions and the recovery of gait, but the effects of specific brain lesions on gait remain unclear. Thus, we investigated the effects of stroke lesions on gait recovery in stroke patients.Materials and MethodsIn total, 30 subjects with stroke were assessed in a retrograde longitudinal observational study. To assess gait function, the functional ambulation category (FAC) was tested four times: initially (within 2 weeks) and 1, 3, and 6 months after the onset of the stroke. Brain lesions were analyzed via overlap, subtraction, and voxel‐based lesion symptom mapping (VLSM).ResultsAmbulation with FAC improved significantly with time. Subtraction analysis showed that involvement of the corona radiata, internal capsule, globus pallidus, and putamen were associated with poor recovery of gait throughout 6 months after onset. The caudate nucleus did influence poor recovery of gait at 6 months after onset. VLSM revealed that corona radiata, internal capsule, globus pallidus, putamen and cingulum were related with poor recovery of gait at 3 months after onset. Corona radiata, internal capsule, globus pallidus, putamen, primary motor cortex, and caudate nucleus were related with poor recovery of gait at 6 months after onset.ConclusionResults identified several important brain lesions for gait recovery in patients with stroke. These results may be useful for planning rehabilitation strategies for gait and understanding the prognosis of gait in stroke patients.
Ostial right coronary chronic total occlusion: Transesophageal echocardiographic guidance for retrograde aortic re‐entry
Authors: Corrigan Frank E. , Karmpaliotis Dimitrios , Samady Habib , Lerakis Stamatios 
Published: October 2017

AbstractAs antegrade options are limited, intervention upon the ostial right coronary artery (RCA) chronic total occlusion (CTO) warrants a retrograde approach. Landmarks for an aggressive approach are concerning as passage of stiff guidewires or electrocautery near the RCA ostium may result in wire passage into structures other than the aorta. We report the first use of transesophageal echocardiography (TEE) to assist retrograde passage of a guidewire into the aorta. For the ostial RCA CTO, TEE guidance may be considered to assist retrograde passage of aggressive guidewires into the aorta.