bluuebunny/crossref_metadata_2025_split huggingface dataset:
Localized measurements of physical parameters within human sperm cells obtained with wide‐field interferometry
Authors: Balberg Michal , Levi Mattan , Kalinowski Ksawery , Barnea Itay , Mirsky Simcha K. , Shaked Natan T. 
Published: January 2017

We developed a new method to identify the separate cellular compartments in the optical path delay (OPD) maps of un‐labeled spermatozoa. This was conducted by comparing OPD maps of fixed, un‐labeled spermatozoa to bright field images of the same cells following labeling. The labeling enabled us to identify the acrosomal and nuclear compartments in the corresponding OPD maps of the cells. We then extracted the refractive index maps of fixed cells by dividing the OPD maps of spermatozoa by the corresponding thickness maps of the same cells, obtained with AFM. Finally, the dry mass of the head, nucleus and acrosome of un‐labeled immobile spermatozoa, was measured. This method provides the ability to quantitatively measure the dry mass of cellular compartments within human spermatozoa. We expect that these measurements will assist label‐free selection of sperm cells for fertilization.
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A Prospective Examination of Perceived Burdensomeness and Thwarted Belongingness As Risk Factors for Suicide Ideation In Adult Outpatients Receiving Cognitive‐Behavioral Therapy
Authors: Teismann Tobias , Glaesmer Heide , von Brachel Ruth , Siegmann Paula , Forkmann Thomas 
Published: January 2017

ObjectiveThe interpersonal‐psychological theory of suicidal behavior posits that 2 proximal, causal, and interactive risk factors must be present for someone to desire suicide: perceived burdensomeness and thwarted belongingness. The purpose of the present study was to evaluate the predictive power of these 2 risk factors in a prospective study.MethodA total of 231 adult outpatients (age: mean = 38.1, standard deviation = 12.3) undergoing cognitive‐behavioral therapy took part in a pretreatment and a midtreatment assessment after the 10th therapy session.ResultsPerceived burdensomeness, thwarted belongingness, and the interaction between these 2 risk factors did not add incremental variance to the prediction of midtreatment suicide ideation after controlling for age, gender, depression, hopelessness, impulsivity, lifetime suicide attempts, and pretreatment suicide ideation. The best predictor of midtreatment suicide ideation was pretreatment suicide ideation.ConclusionResults offer only limited support to the assumptions of the interpersonal theory of suicide.
Parentification and Resilience Among Students With Clinical and Nonclinical Aspirations: A Cross‐Sectional Quantitative Study
Authors: Yew Wan Ping , Siau Ching Sin , Kwong Su Fong 
Published: January 2017

This study examined the relationship between level of parentification and resilience among students with clinical and nonclinical aspirations in Malaysia. A total of 419 college students were surveyed using the Parentification Questionnaire (Jurkovic & Thirkield, ) and Connor–Davidson Resilience Scale (Connor & Davidson, ). Results showed that clinical students were significantly higher in parentification compared with nonclinical students, and parentification positively predicted resilience. Implications for multicultural counseling and research were discussed.Este estudio examinó la relación entre el nivel de parentificación y la resiliencia entre estudiantes con aspiraciones clínicas y no clínicas en Malasia. Se entrevistó a un total de 419 estudiantes universitarios usando el Cuestionario de Parentificación (Jurkovic & Thirkield, ) y la Escala de Resiliencia Connor‐Davidson (Connor & Davidson, ). Los resultados mostraron que los estudiantes clínicos tenían niveles significativamente mayores de parentificación comparados con los estudiantes no clínicos, y la parentificación fue un indicador positivo de resiliencia. Se discuten las implicaciones para la consejería e investigación multiculturales.
Liver imaging reporting and data system category 4 observations in MRI: Risk factors predicting upgrade to category 5
Authors: Sofue Keitaro , Burke Lauren M.B. , Nilmini Viragi , Alagiyawanna Madavi , Muir Andrew J. , Choudhury Kingshuk R. , Jaffe Tracy A. , Semelka Richard C. , Bashir Mustafa R. 
Published: January 2017

PurposeTo identify demographic and imaging features in magnetic resonance imaging (MRI) that are associated with upgrade of Liver Imaging Reporting and Data System (LI‐RADS) category 4 (LR‐4) observations to category 5 (LR‐5), and to assess their effects on risk of upgrade and time to upgrade.Materials and MethodsInstitutional Review Board approval was obtained for this retrospective, dual‐institution Health Insurance Portability and Accountability Act (HIPAA)‐compliant study. Radiologists reviewed 1.5T and 3T MRI examinations for 181 LR‐4 observations in 139 patients, as well as follow‐up computed tomography (CT) and MRI examinations and treatment. A stepwise multivariate Cox proportional hazards model analysis was performed to identify predictive risk factors for upgrade to LR‐5, including patient demographics and LI‐RADS imaging features. Overall cumulative risk of upgrade was calculated by using the Kaplan–Meier method. The cumulative risks were compared in the presence/absence of significant predictive risk factors using the log‐rank test.ResultsThe independent significant predictive risk factors in the 56 LR‐4 observations that upgraded to LR‐5 were mild–moderate T2 hyperintensity (P < 0.001; hazard ratio = 1.84), growth (P < 0.001; hazard ratio = 3.71), and hepatitis C infection (P = 0.02; hazard ratio = 1.69). The overall 6‐month cumulative risk of upgrade was 32.7%. The 6‐month cumulative risk rate was significantly higher in the presence of T2 hyperintensity (P = 0.03; 48.1% vs. 25.4%).ConclusionFor LR‐4 observations, mild–moderate T2 hyperintensity, threshold growth, and hepatitis C infection are associated with significantly higher risk of upgrade to LR‐5. Although mild–moderate T2 hyperintensity was the most useful risk factor for predicting upgrade, actual risk level was only mildly elevated, and the risk of upgrade associated with LR‐4 observations is similar across subtypes.Level of Evidence: 3Technical Efficacy: Stage 5J. MAGN. RESON. IMAGING 2017;46:783–792
Laser alteration on iron sulfides under various environmental conditions
Authors: Weber I. , Böttger U. , Pavlov S. G. , Hübers H.‐W. , Hiesinger H. , Jessberger E. K. 
Published: January 2017

Upcoming lander missions to planetary bodies require new innovative techniques for the in situ investigation of their surfaces and near‐surface materials. In recent years, Raman spectroscopy has been developed to become an excellent laboratory tool for fast petrological and mineralogical investigation of terrestrial and extraterrestrial rocks. Consequently, Raman spectroscopy has successfully been proposed for operation on planetary surfaces. For example, the Raman Laser Spectrometer of the joint European Space Agency and Roscosmos mission ExoMars will, for the first time in space, identify minerals and organic compounds in Martian surface rocks and soils by using Raman spectroscopy.In preparation for space missions, we investigate iron sulfides to measure the influence of various environmental conditions and the effect of laser irradiation itself on the obtained Raman spectra. Iron sulfides are chosen because they are widely disseminated on the Martian surface as known from Martian meteorites, lander missions and remote sensing. They are also present in almost all meteorites as well as on Moon's surface, and they might be present in the rocks of Jupiter's satellites Ganymede and Callisto. We selected the iron di‐sulfides pyrite, marcasite, and chalcopyrite, and the iron mono‐sulfides troilite, and pyrrhotite. Because on Earth in ambient air these iron sulfides are very sensitive to laser irradiation, it is necessary to know how these minerals react during the measurements under conditions that are similar to space environments.Therefore, spectra were taken with various laser power and in various environmental conditions relevant for measurements on Mars, the Moon, and asteroids. These conditions are ambient air, vacuum down to 10−6 mbar, 8 mbar CO2 atmosphere, and temperatures ranging between room temperature (~293 K) and ~10 K. We found that Raman spectra of different iron di‐sulfides are stable under different environmental conditions and with increasing laser power. In contrast, iron sulfides are very sensitive to increasing laser power in ambient air and convert into hematite and magnetite. However, most important for space missions, no effects were found with increasing laser power in vacuum. In addition, a CO2 atmosphere does not affect the Raman spectra for the investigated minerals, a finding particularly important for missions to Mars. Copyright © 2017 John Wiley & Sons, Ltd.
Full discovery: What is the publisher's role?
Authors: Dove John G. 
Published: January 2017

Key points

Our collective authorship and publishing practices do not always end up ensuring that scholarly content is discoverable by readers.
Readers of all kinds rely on a variety of ‘discovery pathways’, such as search engines, library systems, and various electronic links, some of which are blind to the content they desire.
Efforts over the years to improve content discoverability have made great progress, but an increasing amount of freely available content brings up new issues.
The National Information Standards Organization (NISO)’s Discovery to Delivery (D2D) Topic Committee has developed a grid comparing various ways in which content is shared with various ways in which users discover such content.
This article brings to light a few of the current obstacles and opportunities for innovation by publishers, aggregators, search engines, and library systems, and invites Learned Publishing readers to step up and identify others.
Wiener Tauberian theorem for rank one semisimple Lie groups and for hypergeometric transforms
Authors: Pusti Sanjoy , Samanta Amit 
Published: January 2017

AbstractWe prove a genuine analogue of the Wiener Tauberian theorem for , where G is a real rank one noncompact, connected, semisimple Lie group with finite centre. This generalizes the corresponding result on the automorphism group of the unit disk by Y. Ben Natan, Y. Benyamini, H. Hedenmalm, and Y. Weit. We extend this result for hypergeometric transforms and as an application we prove an analogue of Furstenberg theorem on harmonic functions for hypergeometric transforms.
“Why Would I Read a Mobile Review?” Device Compatibility Perceptions and Effects on Perceived Helpfulness
Authors: März Armin , Schubach Sebastian , Schumann Jan H. 
Published: January 2017

ABSTRACTThe proliferation of mobile devices means that mobile‐generated customer reviews are on the rise, though research into their peculiarities and appraisals is rare. With field data and a scenario experiment, the current research demonstrates how recipients perceive mobile‐generated customer reviews fundamentally differently from nonmobile‐generated reviews. First, behavioral field data provide evidence that consumers discount the helpfulness of mobile reviews due to their text‐specific content and style particularities. Second, the scenario experiment shows that identifying a review as written on a mobile device lowers recipients’ perceptions of its value, but only if they use a nonmobile device to read the review. Recipients rely on device information as a source cue to assess compatibility. If they perceive themselves as compatible with the device, recipients perceive the review as more helpful because they attribute the review's content to the quality of the reviewed object; if they regard it as incompatible, recipients assume the review reflects the personal dispositions of the reviewer and discount its helpfulness. Managers of online opinion platforms thus must acknowledge the peculiarities of mobile‐generated reviews and the impact of tagging content as mobile or not.
How Mobile In‐Store Advertising Influences Purchase Intention: Value Drivers and Mediating Effects from a Consumer Perspective
Authors: Bues Mirja , Steiner Michael , Stafflage Marcel , Krafft Manfred 
Published: January 2017

ABSTRACTMobile in‐store advertising is becoming increasingly important, as it offers new options for retailers to communicate with customers at the point of sale. This study investigates how mobile in‐store advertising should be designed in order to be most effective. The authors identify three value drivers (price promotion, location, and personalization) and examine their effect on customers’ purchase intention. The influence of the three value drivers was tested in a large‐scale representative study with a laboratory experimental design. The findings indicate that all three value drivers increase purchase intention. Surprisingly, the authors find that price promotions are the least important value driver, whereas the location of receiving a mobile ad is the strongest driver of purchase intention. An interaction effect between location and personalization was also found to be significant. Personalization close to the product has little impact on purchase intention. The findings have important implications for researchers and retail managers, particularly when designing mobile in‐store advertising campaigns.
Technical Note: A safe, cheap, and easy‐to‐use isotropic diffusion MRI phantom for clinical and multicenter studies
Authors: Pullens Pim , Bladt Piet , Sijbers Jan , Maas Andrew I.R. , Parizel Paul M. 
Published: January 2017

PurposeSince Diffusion Weighted Imaging (DWI) data acquisition and processing are not standardized, substantial differences in DWI derived measures such as Apparent Diffusion Coefficient (ADC) may arise which are related to the acquisition or MRI processing method, but not to the sample under study. Quality assurance using a standardized test object, or phantom, is a key factor in standardizing DWI across scanners.MethodsCurrent diffusion phantoms are either complex to use, not available in larger quantities, contain substances unwanted in a clinical environment, or are expensive. A diffusion phantom based on a polyvinylpyrrolidone (PVP) solution, together with a phantom holder, is presented and compared to existing diffusion phantoms for use in clinical DWI scans. An ADC vs. temperature calibration curve was obtained.ResultsADC of the phantom (808 to 857 ± 0.2 mm2/s) is in the same range as ADC values found in brain tissue. ADC measurements are highly reproducible across time with an intra‐class correlation coefficient of > 0.8. ADC as function of temperature (in Kelvin) can be estimated as with a total uncertainty (95% confidence limit) of ± 1.7%.ConclusionWe present an isotropic diffusion MRI phantom, together with its temperature calibration curve, that is easy‐to‐use in a clinical environment, cost‐effective, reproducible to produce, and that contains no harmful substances.
Numerical modelling of microscopic lubricant flow in sheet metal forming. Application to plane strip drawing
Authors: Carretta Y. , Boman R. , Bech J. , Legrand N. , Laugier M. , Ponthot J.‐P. 
Published: January 2017

SummaryThis paper presents a numerical investigation of microscopic lubricant flows from the cavities to the plateaus of the surface roughness of metal sheets during forming processes. This phenomenon, called micro‐plasto‐hydrodynamic lubrication, was observed experimentally in various situations such as compression sliding tests, strip drawing and cold rolling. It leads to local friction drop and wear reduction. It is therefore critical to achieve a good understanding of this phenomenon. As to move towards that goal, a multiscale fluid–structure interaction model is developed to model lubricant flows at the microscopic scale. These simulations are made possible through the use of the Arbitrary Lagrangian Eulerian (ALE) formalism. In this paper, this methodology is used to study plane strip drawing. The numerical model is able to predict the onset of lubricant escape and the amount of lubricant flowing on the plateaus. Numerical results exhibit good agreement with experimental measurements. Copyright © 2017 John Wiley & Sons, Ltd.
ADHD medications and cardiovascular adverse events in children and adolescents: cross‐national comparison of risk communication in drug labeling
Authors: Sieluk Jan , Palasik Brittany , dosReis Susan , Doshi Peter 
Published: January 2017

AbstractPurposeRegulators approve written medical information for healthcare professionals and consumers, but the consistency of these sources has not been studied. We investigated the consistency of information regarding four cardiovascular risks of attention‐deficit/hyperactivity disorder (ADHD) medications approved in four countries.MethodsProfessional and consumer product labeling for five ADHD medications approved in Australia, Canada, the UK, and the USA were obtained in March/April 2016. Language describing the relationship between medication and elevated blood pressure and/or heart rate, myocardial infarction, stroke, and sudden death was extracted verbatim and classified into one of four categories based on the described relationship between medication and adverse event: “confirmed,” “unconfirmed,” “mixed,” and “not mentioned.” We judged the consistency of messages delivered to healthcare professionals and consumers as either “consistent” or “inconsistent.”ResultsWe obtained 20 healthcare professional labels and 20 corresponding consumer labels for the five ADHD medications registered in all four countries. Not all professional and consumer labeling contained language regarding all four adverse events. Of the 80 theoretically evaluable drug‐risk pairs, 38 (48%) were not evaluable because of absence of mention of the adverse event in the consumer label. For the remaining 42, the potential causal relationship was expressed consistently in professional and consumer labeling in 25 (60%) cases. The cardiovascular risk profile was not described consistently across all four countries for any of the five drugs.ConclusionsProduct labeling provides healthcare professionals and consumers with inconsistent messages regarding the potential causal relationship between stimulant use and specific cardiovascular risks in children and adolescents. Copyright © 2017 John Wiley & Sons, Ltd.
Cover Image, Volume 66, Issue 2
Authors: Tran‐Cong‐Miyata Qui 
Published: January 2017

The cover image, a 3D stationary salami structure of a green/red/black ternary polymer blend and the separated red and green continuous structure, is by QUI TRAN‐CONG‐MIYATA, based on the Editorial In Focus section: Polymer Research at KIT, Japan, DOI: 10.1002/pi.5248.
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A theoretical assignment on excited‐state intramolecular proton transfer mechanism for quercetin
Authors: Yang Dapeng , Yang Guang , Zhao Jinfeng , Zheng Rui , Wang Yusheng , Lv Jian 
Published: January 2017

AbstractIn the present work, we investigate a new chromophore (ie, quercetin) (Simkovitch et al J Phys Chem B 119 [2015] 10244) about its complex excited‐state intramolecular proton transfer (ESIPT) process based on density functional theory and time‐dependent density functional theory methods. On the basis of the calculation of electron densityρ(r) and Laplacian ∇2ρ(r) at the bond critical point using atoms‐in‐molecule theory, the intramolecular hydrogen bonds (O1‐H2⋯O5and O3‐H4⋯O5) have been supported to be formed in the S0state. Comparing the prime structural variations of quercetin involved in its 2 intramolecular hydrogen bonds, we find that these 2 hydrogen bonds should be strengthened in the S1state, which is a fundamental precondition for facilitating the ESIPT process. Concomitantly, infrared vibrational spectra analysis further verifies this viewpoint. In good agreement with previous experimental spectra results, we find that quercetin reveals 2 kinds of excited‐state structures (quercetin* and quercetin‐PT1*) in the S1state. Frontier molecular orbitals depict the nature of electronically excited state and support the ESIPT reaction. Our scanned potential energy curves according to variational O1‐H2and O3‐H4coordinates demonstrate that the proton transfer process should be more likely to occur in the S1state via hydrogen bond wire O1‐H2⋯O5rather than O3‐H4⋯O5because of the lower potential energy barrier 2.3 kcal/mol. Our present work explains previous experimental result and makes up the deficiency of mechanism in previous experiment. In the end, we make a reasonable assignment for ESIPT process of quercetin.
Planar Phase Separation of Weak Polyelectrolyte Brushes in Poor Solvent
Authors: Gao Kai , Kearney Logan T. , Howarter John A. 
Published: January 2017

ABSTRACTPoly(acrylic acid) (PAA) brushes were synthesized on silicon wafer substrates using a silane linker and Z‐group RAFT method, which enables the controlled variation of brush characteristics. Atomic force microscopy (AFM) was used to characterize the brush morphology in the dry state, which ranged from isolated globules to micelles to a continuous film featuring dimples. Surface morphology was primarily determined by total grafted polymer concentration with a critical polymer concentration between 4.5 and 6.5 × 10−23mol/nm2, where the polymer rich regions transition from micellar islands to a continuous film with dimples. However, even at the highest grafting densities and brush strand lengths used in this study, a flat homogenous film was not formed. Morphological consequences of the solvent and thermal history were shown to persist into poorly solvated state after being dried. X‐ray photoelectron spectroscopy (XPS) was used to quantify the degree of remaining salt after drying. It was found that a higher relative amount of salt was retained after drying in the lower grafting density samples. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2017, 55, 370–377
Identification of potential protein quality markers in pathogen inactivated and gamma‐irradiated red cell concentrates
Authors: Chen Deborah , Schubert Peter , Devine Dana V. 
Published: January 2017

PurposePost‐collection manipulations (PCMs) aim to increase blood product safety. However, PCMs improve safety at a cost to quality, causing elevated hemolysis. As hemolysis is linked to red blood cell membrane integrity, a quantitative proteomics approach was employed to assess membrane proteome alterations induced by PCMs.Experimental designThree ABO‐matched whole blood (WB) units were pooled‐and‐split into three identical units. One WB unit was treated with riboflavin/ultraviolet illumination prior to red cell concentrate (RCC) production (RCCWB*). Two WB units were produced into RCC; one was gamma‐irradiated (RCCγ) and the other was left untreated as control (RCCØ). In vitro quality parameters were measured during storage. Membrane protein profiles of RCCØ, RCCγ, and RCCWB* were assessed on selected hemoglobin‐depleted membrane fractions using a quantitative proteomics approach based on iTRAQ.ResultsQuantitative proteomic analysis identified 100 proteins at the membrane, with seven unique proteins exhibiting significant changes in RCCWB* at day 28 of storage. Membrane peroxiredoxin‐2, catalase, and proteasome levels demonstrated robust negative correlation with percentage hemolysis.ConclusionOverall, the in vitro parameters and alterations of membrane protein profiles indicated that pathogen inactivation treatment impacts RCC quality more severely than gamma‐irradiation and that it may induce damage through a predominately oxidative mechanism.