bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rare cause of epileptic encephalopathy: case report of a novel patient with PEHO-like phenotype and CCDC88A gene pathogenic variants
Authors: Papuc Sorina-Mihaela , Glangher Adelina , Erbescu Alina , Arsene Oana Tarta , Arghir Aurora , Budisteanu Magdalena 
Published: September 2024

Abstract
Background
The Coiled-Coil Domain-Containing Protein 88 A (CCDC88A) gene encodes the actin-binding protein Girdin, which plays important roles in maintaining the actin cytoskeleton and in cell migration and was recently associated with a specific form of epileptic encephalopathy. Biallelic protein-truncating variants of CCDC88A have been considered responsible for progressive encephalopathy with edema, hypsarrhythmia, and optic atrophy (PEHO)-like syndrome. To date, only three consanguineous families with loss-of-function homozygous variants in the CCDC88A gene have been reported. The described patients share many clinical features, such as microcephaly, neonatal hypotonia, seizures, profound developmental delay, face and limb edema, and dysmorphic features, with a similar appearance of the eyes, nose, mouth, and fingers.

Case presentation
We report on a child from a nonconsanguineous family who presented with profound global developmental delay, severe epilepsy, and brain malformations, including subcortical band heterotopia. The patient harbored two heterozygous pathogenic variants in the trans configuration in the CCDC88A gene, which affected the coiled-coil and C-terminal domains.

Conclusions
We detail the clinical and cerebral imaging data of our patient in the context of previously reported patients with disease-causing variants in the CCDC88A gene, emphasizing the common phenotypes, including cortical malformations, that warrant screening for sequence variants in this gene.
Student ultrasound education, current view and controversies. Role of Artificial Intelligence, Virtual Reality and telemedicine
Authors: Daum Nils , Blaivas Michael , Goudie Adrian , Hoffmann Beatrice , Jenssen Christian , Neubauer Ricarda , Recker Florian , Moga Tudor Voicu , Zervides Constantinos , Dietrich Christoph Frank 
Published: September 2024

AbstractThe digitization of medicine will play an increasingly significant role in future years. In particular, telemedicine, Virtual Reality (VR) and innovative Artificial Intelligence (AI) systems offer tremendous potential in imaging diagnostics and are expected to shape ultrasound diagnostics and teaching significantly. However, it is crucial to consider the advantages and disadvantages of employing these new technologies and how best to teach and manage their use. This paper provides an overview of telemedicine, VR and AI in student ultrasound education, presenting current perspectives and controversies.
Porto-mesenteric four-dimensional flow MRI: a novel non-invasive technique for assessment of gastro-oesophageal varices
Authors: Karam Rasha , Elged Basma A. , Elmetwally Omar , El-Etreby Shahira , Elmansy Mostafa , Elhawary Mohammed 
Published: September 2024

Abstract
Objectives
To assess the role of 4D flow MRI in the assessment of gastro-oesophageal varices and in the prediction of high-risk varices in patients with chronic liver disease.

Methods
Thirty-eight patients diagnosed with either oesophageal or gastric varices were included in this single-centre prospective study. 4D flow MRI was used to calculate peak flow, average flow and peak velocity at the portal vein confluence (PV1) and hilum (PV2), splenic vein hilum (SV1) and confluence (SV2), and superior mesenteric vein (SMV). PV and SV fractional flow changes were also measured.

Results
ROC analysis revealed that both PV2 average flow and PV fractional average flow change had 100% sensitivity to predict high-risk patients with the PV fractional peak flow change having the widest area under the curve (AUC) and the highest specificity (92.3%). SV1 average flow, SV2 average flow, SV2 peak flow, and SV2 peak velocity increased significantly in patients with oesophageal compared to gastric varices included (p = 0.022, < 0.001, < 0.001 and 0.001, respectively).

Conclusion
Based on certain porto-mesenteric blood flow, velocity, and fractional flow change parameters, 4D flow MRI showed excellent performance in identifying high-risk patients and giving an idea about the grade and location of varices.

Critical relevance statement
Variceal bleeding is a major consequence of unidentified risky upper GI varices. Thus, by identifying and locating high-risk varices early, either oesophageal or gastric, using a non-invasive method like MRI, adverse events might be avoided.

Key Points

4D flow MRI can be used as a potential alternative for endoscopy to predict patients with high-risk varices.

Based on portal vein fractional flow change, splenic flow and velocity, 4D MRI can predict and locate high-risk varices.

Earlier identification of high-risk varices can allow for interventions to prevent adverse events.

Graphical Abstract
Dynamic priority-based bandwidth allocation scheme for machine type communications
Authors: Amitu David Martin , Akol Roseline N , Serugunda Jonathan 
Published: September 2024

AbstractThe burgeoning realm of Machine Type Communications (MTC) has ushered in a paradigm shift in wireless communication, necessitating innovative strategies to efficiently manage diverse application requirements. This paper presents a pioneering Dynamic Priority-based Bandwidth Allocation (DPBA) scheme tailored specifically for MTC scenarios, encompassing both MTC and Human Type Communications (HTC) coexistence. DPBA employs an adaptive framework addressing dynamic MTC traffic, optimizing resource use while meeting latency constraints and sporadic data patterns. By dynamically prioritizing MTC applications based on requirements, the scheme allocates bandwidth for reliable data delivery. DPBA extends to MTC and HTC coexistence, managing diverse quality demands. This underlines its versatility and capacity to serve distinct needs in a shared spectrum. To substantiate its performance, the DPBA scheme is rigorously evaluated against a spectrum of related allocation methods like Proportional Fairness (PF), Static Priority Scheduling (SPS), and the Machine Learning-based Scheme (MLS), DPBA excels in simulations, minimizing packet loss, latency, enhancing throughput and ensuring fairness, surpassing benchmarks. This research underscores the critical importance of tailored bandwidth allocation strategies in advancing MTC and HTC coexistent environments. With its adaptability, efficiency, and remarkable performance, the DPBA scheme emerges as a cornerstone in the trajectory of wireless communication networks, catering to the distinct requirements of both MTC and HTC applications.
Differences in seasonal dynamics, ecological driving factors and assembly mechanisms of planktonic and periphytic algae in the highly urban Fenhe River
Authors: Zhao Kangxu , Wang Wei , Huang Hanjie , Lv Junping , Liu Xudong , Nan Fangru , Shi Ying , Xie Shulian , Feng Jia 
Published: September 2024

Abstract
Background
Algae play important roles in urban river ecosystems and are the cornerstones of most water quality monitoring programs. Thus, a better understanding of algal community dynamics is needed to support sustainable management of water resources in urban rivers.

Results
In this study, we quantified the seasonal variations in planktonic and periphytic algal community structure in the highly urban Fenhe River and identified environmental factors affecting algal community structure and diversity. We monitored planktonic (drifting) and periphytic (attached) algal communities in the Taiyuan section of the Fenhe River over one year. The results indicated that Cyanophyta was the dominant phylum in both communities, followed by Bacillariophyta and Chlorophyta. Significant differences were observed in the composition of the planktonic and periphytic algal communities. In particular, the periphytic algal community was more diverse than the planktonic community. Water temperature and pH were the main environmental factors affecting planktonic and periphytic algal community structure, respectively, while nutrients were the most significant factor affecting planktonic and periphytic algal diversity. Ecological modeling indicated that the variations in the algal communities of the Fenhe River are mainly driven by stochastic processes. A co-occurrence network developed for the communities displayed positive interactions between the planktonic and periphytic algae.

Conclusions
These findings deepen our understanding of the seasonal interaction between planktonic and periphytic algae and the driving factors affecting community structure in the Fenhe River. They also provide a theoretical basis for the managing and protecting water resources in urban river ecosystems.
A novel application of the micro-wire-electro-discharge-grinding (µ-WEDG) method for the generation of tantalum and brass nanoparticles
Authors: Korgal Akash , Karanth P. Navin , Shettigar Arun Kumar , Madhavi J. Bindu 
Published: September 2024

AbstractThe synthesis of a co-precipitated mixture of tantalum and brass nanoparticles (Ta and Cu/Zn) using a micro-wire-electro-discharge-grinding (µ-WEDG) with a combination of multiple process parameters is explained in this article. Tantalum and brass nanoparticles are produced in a dielectric medium Diel-7500 EDM oil. µ-WEDG represents a cutting-edge mechanical micro-machining technique extensively employed for machining micro rods. This method uses a grinding process that expels debris via melting and evaporation. This process disperses a fraction of nanometre-sized debris within the dielectric medium. Traditionally, this debris consisting of nanoparticles has been classified as unwanted substances and subsequently eliminated from the system. However, it now requires a thorough reassessment for possible usage. Hence, the characterization of tantalum and brass nanoparticles is conducted through Field emission Scanning Electron Microscopy (FE-SEM), energy-dispersive spectroscopy (EDS), and X-ray diffraction (XRD) analyses. The process parameters are capacitance, voltage and spindle speed. The investigation reveals that the mean nanoparticle size of produced tantalum nanoparticles range from 25 to 200 nm, while brass nanoparticles range from 300 to 950 nm. Furthermore, a notable correlation is observed between decreasing capacitance and the corresponding reduction in the shape and size of nanoparticles.
Multi-agent system-based framework for an intelligent management of competency building
Authors: Outay Fatma , Jabeur Nafaa , Bellalouna Fahmi , Al Hamzi Tasnim 
Published: September 2024

AbstractTo measure the effectiveness of learning activities, intensive research works have focused on the process of competency building through the identification of learning stages as well as the setup of related key performance indictors to measure the attainment of specific learning objectives. To organize the learning activities as per the background and skills of each learner, individual learning styles have been identified and measured by several researchers. Despite their importance in personalizing the learning activities, these styles are difficult to implement for large groups of learners. They have also been rarely correlated with each specific learning stage. New approaches are, therefore, needed to intelligently coordinate all the learning activities while self-adapting to the ongoing progress of learning as well as to the specific requirements and backgrounds of learners. To address these issues, we propose in this paper a new framework for an intelligent management of the competency building process during learning. Our framework is based on a recursive spiral Assess-Predict-Oversee-Transit model that is orchestrated by a multi-agent system. This system is particularly responsible of enabling smart transitions between learning stages. It is also responsible of assessing and predicting the process of competency building of the learner and, then, making the right decisions about the learning progress, accordingly. Results of our solution were demonstrated via an Augmented Reality app that we created using the Unity3D engine to train learners on Air Conditioner maintenance.
A novel acoustic micro-perforated panel (MPP) based on sugarcane fibers and bagasse
Authors: Beheshti Mohammad Hosein , Khavanin Ali , Jafarizaveh Mostafa , Tabrizi Akram 
Published: September 2024

AbstractNatural materials are becoming a reliable alternative to traditional artificial materials used in sound absorption insulation. The present study was conducted to investigate the acoustic insulation of micro-perforated panel (MPP) based on sugarcane fibers and bagasse as an available and environmentally friendly material. The absorption properties of single- and double-leaf natural micro-perforated panels (MPP) made of bagasse and also nonnatural MPPs made of Plexiglass were measured using an impedance tube based on ISO 10534–2. Then the effect of bagasse and sugarcane fibers composite on the air gap of MPP was investigated. The results showed the peak sound absorption of the bagasse composite is in the range of 1000 to 2000 Hz, and the sugarcane fiber composite has a higher sound absorption coefficient than the bagasse composite. Also, natural MPPs have a higher absorption coefficient than nonnatural MPPs at all frequencies, and as the panel thickness increases, the peak absorption coefficient shifts to lower frequencies. The peak sound absorption coefficient of double-leaf MPPs made of bagasse is 76%, in the range of 160 to 200 Hz. Using sugarcane fiber composite in the air gap of single- and double-leaf natural MPPs causes the absorption peak to shift to frequencies below 100 Hz. According to the results, natural MPPs have a high sound absorption coefficient at low frequencies. These panels can control sounds with much lower frequencies, especially in a double layer and along with cane fiber composite in their air gap.
Effects of Holistically Conceptualised School-Based Interventions on Children’s Physical Literacy, Physical Activity, and Other Outcomes: A Systematic Review
Authors: Jerebine Alethea , Arundell Lauren , Watson-Mackie Kimberley , Keegan Richard , Jurić Petra , Dudley Dean , Ridgers Nicola D. , Salmon Jo , Barnett Lisa M. 
Published: September 2024

Abstract
Background
Schools are a key setting for promoting children’s physical literacy development. This review aimed to identify school-based interventions that adopted a holistic conceptualisation of physical literacy and examine the effects on children’s physical literacy and any other outcomes, including physical activity (PA).

Methods
Searches were conducted in seven databases (APA PsycINFO, EMBASE, ERIC, CINAHL, Global Health, MEDLINE Complete, SPORTDiscus with Full Text), and Google and Google Scholar, to identify articles published since 1/1/2017. Studies were included if they (i) adopted a holistic conception of physical literacy as represented by the Australian Physical Literacy Framework (APLF), (ii) were grounded in movement, (iii) assessed three or more domains of learning (either quantitatively or qualitatively), and (iv) included children aged 5–14 years. Quantitative research designs needed to provide pre-and post-intervention measures, whereas qualitative designs (e.g. post-intervention interviews) did not. Study selection, data extraction and quality assessment were conducted independently by teams of two authors. For intervention effects, quantitative and qualitative data were synthesised separately. For quantitative data, level of evidence for intervention effects was assessed by physical literacy domain and/or elements/items by examining the proportion of tests with a significant change in the expected direction. Qualitative data were synthesised using the framework synthesis method and mapped to a framework that included APLF domains/elements, PA, and additional outcomes.

Results
Twelve interventions with 1,427 participants from seven countries were identified: six physical education-based, three afterschool, one structured recess, and two multicomponent. All studies assessed the physical domain quantitatively, with strong positive evidence of intervention effects for the controlled designs (10 of 15 tests). For the affective and cognitive domains, evidence was mixed, and there was no evidence for interventions improving the social components of children’s physical literacy (although this was understudied). Most studies assessed PA and one measured cognitive performance; however, there was no evidence for positive intervention effects (i.e. ≥35% of tests reporting an improvement) for either outcome. Five studies assessed intervention effects qualitatively, with positive results reported for all physical literacy domains, PA, and cognitive performance.

Conclusions
Holistic interventions in schools can improve the physical domain of children’s physical literacy. For wider benefits, future interventions should aim to develop all facets of physical literacy, especially domains of learning less frequently targeted and examined.

Trial Registration
PROSPERO CRD42022351317.
What do we Know about Complex-Contrast Training? A Systematic Scoping Review
Authors: Thapa Rohit K. , Weldon Anthony , Freitas Tomás T. , Boullosa Daniel , Afonso José , Granacher Urs , Ramirez-Campillo Rodrigo 
Published: September 2024

Abstract
Background
The complex-contrast training (CCT) method utilizes two exercises with different loads and movement velocities in a set-by-set fashion to induce multiple neuromuscular adaptations. The speculated primary mechanism involves the post-activation potentiation or post-activation performance enhancement (PAPE) of the muscles used during the heavy load (low velocity) exercise, thereby improving the performance of lower load (high velocity) exercise. However, no previous study has attempted to systematically synthesize the available evidence on CCT (e.g., if post-activation potentiation or PAPE was measured during the training sessions during the intervention period). This study aimed to synthesize the available evidence on CCT using a systematic scoping review approach. More specifically, we identified gaps in the literature using an evidence gap map (EGM), and provided future directions for research.

Methods
Three electronic databases (PubMed, Scopus, and Web of Science) were searched up to 20th February 2024. Data were extracted under a PICO framework: (a) Participants-related data (e.g., age, sex, type of sport); (b) Intervention-related data (e.g., duration of training); (c) Comparators (when available); and (d) Outcomes (e.g., measures of physical fitness). Interactive EGMs were created using the EPPI mapper software.

Results
From the 5,695 records screened, 68 studies were eligible for inclusion, involving 1,821 participants (only 145 females from 5 studies). All CCT interventions lasted ≤ 16 weeks. More than half of the studies assessed countermovement jump, sprint, and maximal strength performances. No studies were identified which examined upper-body CCT exercises alone, and no study assessed PAPE during the CCT sessions. Overall, the available evidence was rated with a low level of confidence.

Conclusions
In conclusion, whether CCT produces a PAPE that translates into longitudinal performance gains remains unclear. Moreover, the available evidence on the effects of CCT on various outcomes provides low confidence regarding the most effective way to implement this training method, particularly among females, and beyond long-term interventions.
Role of Cardiorespiratory Fitness, Aerobic, Exercise and Sports Participation in Female Cognition: A Scoping Review
Authors: Weber Vinicius Muller Reis , Queiroga Marcos Roberto , Puranda Jessica L. , Semeniuk Kevin , Macdonald Meaghan Lindsay , Dantas Diego Bessa , da Silva Danilo Fernandes , Adamo Kristi Bree 
Published: September 2024

Abstract
Background
The impact of cardiorespiratory fitness (CRF) on cognition is thought to be mediated by brain-derived neurotrophic factor. Aerobic exercise can increase CRF through various activities, including sports participation. The relationship between these factors in females has yet to be elucidated.

Objective
This review aims to map the current literature on the effects of aerobic exercise, sports participation, and CRF in healthy adult females, with sub-topics of pregnancy and menstrual cycle periodicity.

Methods
A scoping review of the literature was conducted following PRISMA guidelines and the PCC mnemonic (population, concept, and context). The following five databases were screened: CINAHL, Medline, Web of Science, SPORTDiscus, and Scopus. Eligible articles included healthy adult females, investigated aerobic exercise, sports participation or CRF, and linked outcomes to cognition. Data from included manuscripts was extracted and analyzed. Two sub-population groupings (pregnant individuals and menstrual cycle) were established to further aid the interpretation of the findings.

Results
Of the 300 titles and abstracts screened, 74 were eligible for full-text screening, and 28 were included in the scoping review. Of the 28 included, 14 did not control for or report on menstrual cycle phase or sex hormones.

Conclusion
This scoping review found an inverse ‘U’ relationship between aerobic exercise and cognition, demonstrating an optimal dose of aerobic exercise to benefit cognitive functions. As estrogen may impact the relationship between CRF and neural growth factors, more research is needed on this pathway, independent of the menstrual cycle, to determine potential beneficial effects. It is currently unknown whether sports participation can independently impact cognition.
Vascular access in a post-lung transplant patient on maintenance hemodialysis: a case report
Authors: Kawamura Mariko , Nakamura Motonobu , Matsuura Ryo , Odawara Motoki , Kurata Yu , Sakashita Midori , Yamada Daisuke , Hamasaki Yoshifumi , Konoeda Chihiro , Sato Masaaki , Kume Haruki , Nangaku Masaomi 
Published: September 2024

Abstract
Background
An arteriovenous fistula (AVF) is the most common type of vascular access for hemodialysis. As it causes volume overload and sometimes increases pulmonary artery pressure, it is unsuitable for some patients. Herein, we describe a patient with acute kidney disease who required maintenance hemodialysis with vascular access other than an AVF owing to post-lung transplant pulmonary hypertension.

Case presentation
A 50-year-old man with interstitial pneumonia underwent living-donor lobar lung transplantation at our hospital. Weaning from venoarterial extracorporeal membrane oxygenation was achieved; however, the patient required mechanical ventilation owing to pulmonary hypertension. He developed acute kidney disease and required maintenance hemodialysis with sustainable vascular access. Although echocardiography showed a normal ejection fraction, we expected volume overload after arteriovenous access construction to worsen his pulmonary hypertension because of his inadequate pulmonary vascular bed. Therefore, a tunneled central vein catheter was implanted into the right femoral vein as a bridge, and superficialization of the right brachial artery was performed for long-term vascular access.

Conclusions
As this patient had sustained post-transplant pulmonary hypertension and small grafts, we avoided creating arteriovenous access because of concern over the aggravation of pulmonary hypertension. Evaluation of right heart function and pulmonary hypertension is important before arteriovenous access construction.