bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bedside Interprofessional Rounding
Authors: Burdick Kailee , Kara Areeba , Ebright Patricia , Meek Julie 
Published: February 2017

Background: Bedside interprofessional rounding is gaining ground as a means to improve collaboration and patient outcomes, yet little is known regarding patients’ perceptions of the practice. Methods: This descriptive study used individual patient interviews to elicit views on interprofessional rounding from 35 patients at a large, urban hospital. Results: The findings identified three major categories: 1) about the rounding process; 2) clinical information; and 3) the impact/value of bedside inter-professional rounding. Discussion: Intentionally eliciting and responding to our patients’ views of interprofessional rounding may help us design methods that are patient centered and effective.
Granulocyte colony-stimulating factor mobilizes dormant hematopoietic stem cells without proliferation in mice
Authors: Bernitz Jeffrey M. , Daniel Michael G. , Fstkchyan Yesai S. , Moore Kateri 
Published: February 2017

Key Points
G-CSF mobilizes dormant HSCs without proliferation. Transplantation defects of mobilized peripheral blood-derived hematopoietic stem and progenitor cells are divisional history independent.
Runx transcription factors in the development and function of the definitive hematopoietic system
Authors: de Bruijn Marella , Dzierzak Elaine 
Published: February 2017

AbstractThe Runx family of transcription factors (Runx1, Runx2, and Runx3) are highly conserved and encode proteins involved in a variety of cell lineages, including blood and blood-related cell lineages, during developmental and adult stages of life. They perform activation and repressive functions in the regulation of gene expression. The requirement for Runx1 in the normal hematopoietic development and its dysregulation through chromosomal translocations and loss-of-function mutations as found in acute myeloid leukemias highlight the importance of this transcription factor in the healthy blood system. Whereas another review will focus on the role of Runx factors in leukemias, this review will provide an overview of the normal regulation and function of Runx factors in hematopoiesis and focus particularly on the biological effects of Runx1 in the generation of hematopoietic stem cells. We will present the current knowledge of the structure and regulatory features directing lineage-specific expression of Runx genes, the models of embryonic and adult hematopoietic development that provide information on their function, and some of the mechanisms by which they affect hematopoietic function.
The clinical spectrum of Erdheim-Chester disease: an observational cohort study
Authors: Estrada-Veras Juvianee I. , O’Brien Kevin J. , Boyd Louisa C. , Dave Rahul H. , Durham Benjamin H. , Xi Liqiang , Malayeri Ashkan A. , Chen Marcus Y. , Gardner Pamela J. , Alvarado Enriquez Jhonell R. , Shah Nikeith , Abdel-Wahab Omar , Gochuico Bernadette R. , Raffeld Mark , Jaffe Elaine S. , Gahl William A. 
Published: February 2017

Key Points
ECD varies in terms of age of onset, clinical presentation, manifestations, organ involvement, disease severity, and survival. ECD is a neoplasm and should be adopted by the field of hematology-oncology following the World Health Organization reclassification.
Inherited and Uncommon Causes of Stroke
Authors: Majersik Jennifer Juhl 
Published: February 2017

ABSTRACT

Purpose of Review: This article is a practical guide to identifying uncommon causes of stroke and offers guidance for evaluation and management, even when large controlled trials are lacking in these rarer forms of stroke.

Recent Findings: Fabry disease causes early-onset stroke, particularly of the vertebrobasilar system; enzyme replacement therapy should be considered in affected patients. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), often misdiagnosed as multiple sclerosis, causes migraines, early-onset lacunar strokes, and dementia. Moyamoya disease can cause either ischemic or hemorrhagic stroke; revascularization is recommended in some patients. Cerebral amyloid angiopathy causes both microhemorrhages and macrohemorrhages, resulting in typical stroke symptoms and progressive dementia. Pregnancy raises the risk of both ischemic and hemorrhagic stroke, particularly in women with preeclampsia/eclampsia. Pregnant women are also at risk for posterior reversible encephalopathy syndrome (PRES), reversible cerebral vasoconstriction syndrome, and cerebral venous sinus thrombosis. Experts recommend that pregnant women with acute ischemic stroke not be systematically denied the potential benefits of IV recombinant tissue plasminogen activator.

Summary: Neurologists should become familiar with these uncommon causes of stroke to provide future risk assessment and family counseling and to implement appropriate treatment plans to prevent recurrence.
Cost-Effective Quality Assurance in Crowd Labeling
Authors: Wang Jing , Ipeirotis Panagiotis G. , Provost Foster 
Published: February 2017

The emergence of online paid micro-crowdsourcing platforms, such as Amazon Mechanical Turk, allows on-demand and at-scale distribution of tasks to human workers around the world. In such settings, online workers come and complete small tasks posted by employers, working for as long or as little as they wish, a process that eliminates the overhead of hiring (and dismissal). This flexibility introduces a different set of inefficiencies: verifying the quality of every submitted piece of work is an expensive operation that often requires the same level of effort as performing the task itself. A number of research challenges arise in such settings. How can we ensure that the submitted work is accurate? What allocation strategies can be employed to make the best use of the available labor force? How can we appropriately assess the performance of individual workers? In this paper, we consider labeling tasks and develop a comprehensive scheme for managing the quality of crowd labeling: First, we present several algorithms for inferring the true classes of objects and the quality of participating workers, assuming the labels are collected all at once before the inference. Next, we allow employers to adaptively decide which object to assign to the next arriving worker and propose several heuristic-based dynamic label allocation strategies to achieve the desired data quality with significantly fewer labels. Experimental results on both simulated and real data confirm the superior performance of the proposed allocation strategies over other existing policies. Finally, we introduce two novel metrics that can be used to objectively rank the performance of crowdsourced workers after fixing correctable worker errors and taking into account the costs of different classification errors. In particular, the worker value metric directly measures the monetary value contributed by each label of a worker toward meeting the quality requirements and provides a basis for the design of fair and efficient compensation schemes. The online appendix is available at https://doi.org/10.1287/isre.2016.0661 .
Sequestration of Catechol and Pentachlorophenol by Mechanochemically Treated Kaolinite
Authors: Ancona Valeria , Di Leo Paola , Pizzigallo Maria Donata Rosa 
Published: February 2017

AbstractThe pollution of soils by organic contaminants, such as phenols, is a serious problem because of the high toxicity and persistence in the environment. Mechanochemical treatments (MTs) of polluted soils with minerals, such as clays and oxides, which have surfaces that exhibit catalytic properties, have been suggested to be a new useful strategy to promote both organic and inorganic pollutant degradation. Nevertheless, much still remains to be studied about the capability of clays to promote pollutant removal by means of the mechanochemical activation of the mineral surfaces. This work investigates the efficiency of the mineral kaolinite in promoting the sequestration of catechol (CAT) and pentachlorophenol (PCP) by MT. A well crystallized kaolinite (KGa-1b) was milled for prolonged times with different amounts of organic molecules so as to obtain two different clay:organic compound ratios. Prolonged grinding and a higher clay mineral:organic compound ratio were found to be more effective in promoting a stronger removal than simple contact. After 1 h of mechanochemical treatment, the PCP and CAT removal percentages were 32% and 20%, respectively. Additionally, a 7-day undisturbed incubation of the milled mixtures produced a trend for increased CAT removal (up to 40%). The interaction mechanism between kaolinite and each organic compound (i.e. CAT and PCP) after a MT was inferred by integrating information from spectroscopic, diffractometric, and chromatographic analyses. X-ray diffraction and Fourier-transform infrared data suggested a strong interaction between CAT and KGa-1b. This interaction mechanism likely occurs through the formation of an inner-sphere complex by H-bonding between the organic molecules and the oxygens of the kaolinite tetrahedral sheet. On the other hand, a weak interaction (i.e. van der Waals type) can occur between the KGa-1b O-planes and the PCP molecules, which likely bind to the external surfaces of KGa-1b.
Applying the Universal Design for Learning Framework for Individuals With Intellectual Disability: The Future Must Be Now
Authors: Smith Sean J. , Lowrey K. Alisa 
Published: February 2017

Abstract
The current research in Universal Design for Learning (UDL) for students with intellectual disability (ID) is briefly summarized and considered in light of the national goals presented by the American Association on Intellectual and Developmental Disabilities (AAIDD) in this article. Additionally, an action plan is provided for researchers and practitioners to extend knowledge on the implementation of the UDL framework inclusive of individuals with ID.
Closed-Tube PCR with Nested Serial Invasion Probe Visualization Using Gold Nanoparticles
Authors: Wang Jianping , Zou Bingjie , Ma Yinjiao , Ma Xueping , Sheng Nan , Rui Jianzhong , Shao Yang , Zhou Guohua 
Published: February 2017

Abstract

BACKGROUND
Detecting DNA biomarkers related to personalized medicine could improve the outcome of drug therapy. However, personalized medicine in a resource-restrained hospital is very difficult because DNA biomarker detection should be performed by well-trained staff and requires expensive laboratory facilities.

METHODS
We developed a gold nanoparticle–based “Tube-Lab” to enable DNA analysis in a closed tube. Gold nanoparticle–modified probes (GNPs) were used to construct an inexpensive and simple DNA sensor for signal readout. The method consists of 3 steps (template amplification, sequence identification, and GNP-based signal readout), bridged by an invasive reaction. With temperature control at each step, the 3 reactions proceed sequentially and automatically in a closed tube without any liquid transfer. We used Tube-Lab to detect different biomarkers in blood, tissue, and plasma, including US Food and Drug Administration–approved pharmacogenomic biomarkers (single nucleotide polymorphisms, somatic mutations).

RESULTS
The combination of PCR-based template replication and invader-based signal amplification allowed detection of approximately 6 copies of input DNA and the selective pick up 0.1% mutants from large amounts of background DNA. This method highly discriminated polymorphisms and somatic mutations from clinical samples and allowed a “liquid biopsy” assay with the naked eye.

CONCLUSIONS
Tube-Lab provides a promising and cost-effective approach for DNA biomarker analysis, including polymorphisms and somatic mutations from blood DNA, tissue DNA, or circulating tumor DNA in plasma, which are critical for personalized medicine.
O PROCESSO DE SEMIFORMAÇÃO NA EDUCAÇÃO: REFLEXÕES POSSÍVEIS E NECESSÁRIAS NA RELAÇÃO INFÂNCIA E INDÚSTRIA CULTURAL.
Authors: Silva Anilde Tombolato Tavares da 
Published: February 2017

Este artigo insere-se num panorama contemporâneo que embasa a essência da infância permeada pela indústria cultural buscando problematizar sua correlação entre a produção de saberes culturais fragmentados que refletem na semiformação e numa pedagogia parcializada na escola contemporânea. Amparados pelo pensamento de Max Horkheimer e Theodor Adorno buscamos lançar um olhar mais atento e crítico para a educação contemporânea que sob a égide da bandeira da formação do indivíduo crítico e transformador, submete-se passivamente ao processo de semiformação e conformação diante dos encantos que se produzem através da Indústria Cultural. Desta forma, confrontar os desafios postos no campo da educação e da prática educativa, os limites e a possibilidade de se assumir a escola como espaço de produção do novo, do não dito, do não pensado em detrimento do que já está instituído.
SÓCRATES, IVAN ILITCH E A EXPERIÊNCIA DO PENSAR FILOSÓFICO
Authors: Miranda José Valdinei Albuquerque 
Published: February 2017

Resumo: Este trabalho tem por objetivo discutir a experiência do pensar filosófico a partir da obra A morte de Ivan Ilitch de Lev Tolstoi e Apologia de Sócrates de Platão. Com estilos diferentes, esses escritos abordam o tema da experiência filosófica, tendo como horizonte de análise a proximidade da morte. Portanto, encontramos nestas duas experiências, um pensar filosófico que se volta para problematizar o sentido da vida em um tempo de proximidade da morte. A experiência de Ivan Ilitch direciona-se a uma profunda análise filosófica de sua existência, permitindo colocar em questão a condição de liberdade e aprisionamento do homem moderno, enquanto que a experiência filosófica de Sócrates nos deixa como herança a sua autêntica preocupação ética com a formação dos jovens atenienses e o valor de uma vida justificada filosoficamente.
Experimental temperature manipulations alter songbird autumnal nocturnal migratory restlessness
Authors: Berchtold Adrienne , Nightingale Ira , Vandermeer Caitlin , MacDougall-Shackleton Scott A. 
Published: February 2017

AbstractMigrating birds may respond to a variety of environmental cues in order to time migration. During the migration season nocturnally migrating songbirds may migrate or stop-over at their current location, and when migrating they may vary the rate or distance of migration on any given night. It has long been known that a variety of weather-related factors including wind speed and direction, and temperature, are correlated with migration in free-living birds, however these variables are often correlated with each other. In this study we experimentally manipulated temperature to determine if it would directly modulate nocturnal migratory restlessness in songbirds. We experimentally manipulated temperature between 4, 14, and 24°C and monitored nocturnal migratory restlessness during autumn in white-throated sparrows (Zonotrichia albicollis). White-throated sparrows are relatively shortdistance migrants with a prolonged autumnal migration, and we thus predicted they might be sensitive to weatherrelated cues when deciding whether to migrate or stopover. At warm temperatures (24°C) none of the birds exhibited migratory restlessness. The probability of exhibiting migratory restlessness, and the intensity of this restlessness (number of infra-red beam breaks) increased at cooler (14°C, 4°C) temperatures. These data support the hypothesis that one of the many factors that birds use when making behavioural decisions during migration is temperature, and that birds can respond to temperature directly independently of other weather-related cues.
Somatisms with the LexemesLábin Hungarian,Nogain Serbian, andLeg/Footin English
Authors: Halupka-Rešetar Sabina , Andrić Edit 
Published: February 2017

AbstractSomatisms are phraseologisms which contain at least one body-part term as a constituent. They make up a considerable part of the phrasemes of any language. In this paper, we focus on the extent to which the equivalent(s) of the termláboccur(s) in Serbian and English somatisms. The research is based on a corpus extracted from both monolingual and bilingual phraseological dictionaries of Hungarian, Serbian, and English. The data are analysed primarily from a cognitive point of view, with the aim of establishing whether the three languages are comparable in terms of the meaning of the idiom as a whole. Degrees of equivalence are established based on whether there is an idiomatic expression in Serbian/English containing the lexemenogaorleg/foot, respectively. Another issue addressed in the paper is the choice of the English term (legvsfoot) in somatisms and the question of whether this choice is arbitrary. Though structure is of secondary importance only, we also take it into account in establishing the degree of equivalence between the items listed in the corpus. Lastly, we stress the similarities and differences noted in the way the body-part terms mentioned are employed in the phraseologisms of the three languages.
Democracy's Twin Challenges: Hans Kelsen and the Problem of Extremist Speech
Authors: Hong Quoc Loc 
Published: February 2017

Abstract
It is well-known that democracy's enemies could rely on the democratic right to free speech to destroy democracy itself. The classic dilemma to be solved, then, is the question whether democracy could defend itself against hostile speech in a way, which would not also endanger the right that forms its own political heart.
What makes the resolution of this dilemma such an arduous task is the principle of consent, which has traditionally constituted democracy's source of legitimacy. This principle is precisely what forms the theoretical Achilles' heel in democracy's self-defense as well, should enemies of this political system choose to pursue its destruction by means of the ballot box. Under that scenario, they would rely on democratic liberties in general, and the right to free speech in particular, to conquer power through the process of majority formation, and subsequently proceed to abolish the process that has made possible their conquest of power in the first place. If democratic government, however, seeks to neutralize this threat by restricting or suspending the democratic rights of democracy's enemies, then it would expose itself to the allegation of betraying the very principle, which constitutes the source of its legitimacy. Democracy's enemies could, after all, credibly allege that laws which are specifically enacted to deprive them of the rights to democratic participation cannot somehow be rooted in their own consent, whereas consent is a sine qua non for the democratic legitimacy of a law. The first challenge to be addressed, therefore, is whether democracy may be able to defend itself against hostile speech in a selfconsistent way.
Related to this is the challenge of how to prevent democracy's efforts at selfdefense from degenerating into a suppression of political dissent in general. Would it be possible for a democratic government to combat extremist speech without endangering the right to free speech itself? This second challenge is one that we have to face whenever a democratic government feels compelled to take measures to defend itself against its enemies. As Susanne Baer has pointed out, “a state engaged in self-defence tends to go too far.”
Drawing on a theory of democracy elaborated by Hans Kelsen under the Weimar Republic, we shall argue in this Article that it is entirely possible for a democratic regime to both suppress the expression of antidemocratic ideas and preserve freedom of speech at the same time.
Public Corruption: Limiting Criminal Immunity of Legislative, Executive and Judicial Officials in Europe
Authors: Hoppe Tilman 
Published: February 2017

Abstract
The constitutions of European states often contain too many categories of officials covered by too broadly defined immunities. At the same time, there is consensus among international organizations that immunities have to be limited to allow effective prosecution of corruption offences. This article examines how public law in European states could limit criminal immunities for officials.
Constitutional Right to Property in Changing Times: The Indian Experience
Authors: Babu R. Rajesh 
Published: February 2017

Abstract
The constitutional right to property has undergone a significant change since India's independence. In the past few decades, the guarantee of property for both alien and domestic right holders went for considerable dilution to sanction the unrestrained power of eminent domain. The arbitrary expropriation of property was justified in the then social and political context of a nascent state. However, since India embarked on the path of liberalization with the policy of promoting international trade and foreign investments, there appeared a progressive and selective modification if its legal regime on property rights to favour alien property and corporate interests. Part of the policy shift involved guarantee and strengthening of the legal environment for protection of foreign property and investment. India's international commitments under the WTO Agreements and several investment protection treaties guaranteed capital and IP exporting states safe and secure property rights in the host state - India, much beyond the existing protection for citizen's property. Remedies for breach and standard of compensation for expropriation, direct or indirect, were judged by international rules and practices, beyond the control of local courts. To the extent that international expropriation and compensation rules provide foreign investors and IPR holders with stronger rights than India’s laws, they are also likely to provide them with stiffer property rights. In addition, change was evident in the nature of ownership of expropriated property. Nationalization (state ownership), which was the primary character of expropriations, was replaced by ‘corporate’ ownership with no respect for public purpose or just compensation. The recent stints of compulsory acquisition of land for SEZ underline the ‘reverse-discrimination’ or double standards perpetrated by the Indian state. The paper attempts to highlight this paradox in India’s property rights regime in the changing global context. The paper argues for a constitutional rethinking on right to property, in the post liberalization context, considering the new social and political realities, particularly from the viewpoint of individual private owners whose identity and livelihood are attached to the property.
Constitutional recognition of the agrarian collective and their rights to govern mineral resources in South Sudan
Authors: Carleton Alexandra 
Published: February 2017

Abstract
Both the ICCPR and the African Charter embody, as a primary principle, the right of a peoples' to freely dispose of their natural wealth and resources (article 1(2) and article 21(1) respectively). Whilst hotly debated as to its legal and political status, operationalising a right could enable agrarian communities to contest the disposal of their mineral wealth. However, such a right ought to be embodied in the constitution, where its alterability is perhaps less subject to political change. Without constitutional standing for collectives to assert claims over land, the State could potentially lease or sell mineral rights (sometimes to multiple extractors at once) irrespective of the environmental, labour and economic considerations.
The secession of South Sudan is demonstrative of the South Sudanese peoples' active reclamation of their natural (and substantial mineral) wealth. This article is a critique of whether the new Transitional Constitution of South Sudan (TCRSS) effectively embodies and operationalises article 1(2) of the ICCPR. It concludes that the TCRSS is dedicated to articulating and protecting (competing) agrarian interests in land and natural resources and in so doing demonstrates the reality of multiple and overlapping mineral and land interests.