bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of Race With Referral Disparities for Patients With Diabetic Foot Ulcers at an Institution Serving Rural and Urban Populations
Authors: Khaleel Mubinah , Garlapaty Ashwin , Hawkins Sam , Cook James L. , Schweser Kyle , Rucinski Kylee 
Published: September 2024

Background: Racial minorities are more likely to develop type 2 diabetes and experience associated microvascular complications. Non-Hispanic Blacks and Hispanics initially present with more severe diabetic foot ulcers (DFUs) and peripheral artery disease (PAD), with an associated 10-fold increase in risk for lower extremity amputation within the first year after diagnosis. This study was designed to determine if race is associated with a failure to refer to specialists for DFU treatment, and the severity of DFU at the time of initial presentation. Methods: Patients were identified from the medical record based on a diagnosis related to diabetic foot complications between January 1, 2018, and June 1, 2023, in the family medicine, endocrinology, orthopaedic, or emergency clinics at a Midwest Academic Hospital serving rural and urban populations. Patients self-reported race, demographics, severity of ulcer based on Wagner ulcer scale at time of referral, eventual amputation status, and measures of social determinants of health including the national Area Deprivation Index (ADI) and Rural-Urban Commuting Area (RUCA) codes were manually extracted and analyzed for correlations with referral status. Results: A total of 597 patients were eligible for inclusion. Race was not associated with lower referral rates ( P > .99) or source of referral ( P = .58) to specialty clinic and ulcer severity at initial examination ( P = .34). Patients who initially presented to the emergency department had more severe ulcers ( P = .016), and higher severity was significantly associated with lower limb amputation vs mild ulcers (odds ratio = 38.8, P = .02). No significant differences in referral source or severity of ulcer at presentation were seen for sex, age, marital status, insurance type, rural status, ADI, time from referral to appointment, or eventual amputation. Conclusion: In this study, we found that patient race was not associated with severity of DFU at presentation or subsequent referral to a Midwest academic specialty orthopaedic clinic for care. Level of Evidence: Level III, retrospective review.
Balance Sparse Decomposition Method with Nonconvex Regularization for Gearbox Fault Diagnosis
Authors: Huang Weiguo , Wang Jun , Du Guifu , Wu Shuyou , Zhu Zhongkui 
Published: September 2024

AbstractAs an important part of rotating machinery, gearboxes often fail due to their complex working conditions and harsh working environment. Therefore, it is very necessary to effectively extract the fault features of the gearboxes. Gearbox fault signals usually contain multiple characteristic components and are accompanied by strong noise interference. Traditional sparse modeling methods are based on synthesis models, and there are few studies on analysis and balance models. In this paper, a balance nonconvex regularized sparse decomposition method is proposed, which based on a balance model and an arctangent nonconvex penalty function. The sparse dictionary is constructed by using Tunable Q-Factor Wavelet Transform (TQWT) that satisfies the tight frame condition, which can achieve efficient and fast solution. It is optimized and solved by alternating direction method of multipliers (ADMM) algorithm, and the non-convex regularized sparse decomposition algorithm of synthetic and analytical models are given. Through simulation experiments, the determination methods of regularization parameters and balance parameters are given, and compared with the L1 norm regularization sparse decomposition method under the three models. Simulation analysis and engineering experimental signal analysis verify the effectiveness and superiority of the proposed method.
Transmission and Dissipation of Vibration in a Dynamic Vibration Absorber-Roller System Based on Particle Damping Technology
Authors: He Dongping , Xu Huidong , Wang Ming , Wang Tao 
Published: September 2024

AbstractThe research of rolling mill vibration theory has always been a scientific problem in the field of rolling forming, which is very important to the quality of sheet metal and the stable operation of equipment. The essence of rolling mill vibration is the transfer of energy, which is generated from inside and outside. Based on particle damping technology, a dynamic vibration absorber (DVA) is proposed to control the vertical vibration of roll in the rolling process from the point of energy transfer and dissipation. A nonlinear vibration equation for the DVA-roller system is solved by the incremental harmonic balance method. Based on the obtained solutions, the effects of the basic parameters of the DVA on the properties of vibration transmission are investigated by using the power flow method, which provides theoretical guidance for the selection of the basic parameters of the DVA. Furthermore, the influence of the parameters of the particles on the overall dissipation of energy of the particle group is analyzed in a more systematic way, which provides a reference for the selection of the material and diameter and other parameters of the particles in the practical application of the DVA. The effect of particle parameters on roll amplitude inhibition is studied by experiments. The experimental results agree with the theoretical analysis, which proves the correctness of the theoretical analysis and the feasibility of the particle damping absorber. This research proposes a particle damping absorber to absorb and dissipate the energy transfer in rolling process, which provides a new idea for nonlinear dynamic analysis and stability control of rolling mills, and has important guiding significance for practical production.
Optimizing model selection across global countries for managing pesticide emission and surface freshwater quality: a hierarchical screening approach
Authors: Huang Yabi , Li Zijian 
Published: September 2024

AbstractPesticides in surface freshwater primarily originate from their emissions in agricultural lands, potentially leading to violations of surface freshwater quality standards. To aid global regulatory agencies in effectively managing surface freshwater quality by estimating and controlling pesticide emission rates, this study proposes a hierarchical screening approach for countries and regions worldwide to select appropriate modeling tools. Hierarchical indicators are introduced to classify countries globally, considering their spatial distribution areas, pesticide emission conditions, and legislative systems. Consequently, different categories of countries are matched with suitable model groups, such as the standard model group for regulatory scenarios, the general model group for continental scenarios, and the advanced model group with high spatial resolution. Results indicated that a total of 193 countries worldwide were categorized into six country groups, of which 153, 34, and 6 countries were found to fit the standard, general, and advanced model groups, respectively, based on the model assignments for these country groups. Furthermore, 12 commonly used pesticides were selected to demonstrate the back-calculation process, which estimates the pesticide emission rate (input) by pesticide surface freshwater quality standards (output) by standard and general model groups. The Advanced model group was not applied in this process due to its intensive computation. An approximate approach was developed to simplify the calculation of the emission rate factor of pesticides using the PWC and TOXSWA selected in the standard model group as well as SWAT in the general model group, serving as a demonstration. This approach can be applied to control pesticide emission rates from surface freshwater quality standards across countries that fit in the standard and general model groups. The results highlight that pesticide fate models selected through the hierarchical screening approach, can assist global countries in establishing a quantitative relationship between pesticide emission rates and surface freshwater quality standards, which can help global agencies manage pesticide emissions and freshwater quality from a legal perspective. There is a need to update and simplify suitable advanced model for calculation demonstration in future studies to aid in pesticide management. Further research is needed to thoroughly investigate pesticide emissions and freshwater residue concentrations under varying conditions.
Testing microbial pest control products in bees, a comparative study on different bee species and their interaction with two representative microorganisms
Authors: Wueppenhorst Karoline , Nack Kevin , Erler Silvio , Pistorius Jens , Alkassab Abdulrahim T. 
Published: September 2024

Abstract
Background
The evaluation of the impact of pesticides on non-target species, like bees, is a crucial factor in registration procedures. Therefore, standardized test procedures have been developed on OECD level assessing the effects of chemicals on honey bees or bumble bees. Unfortunately, these protocols cannot directly be adapted for testing products that contain microorganisms. Interest in the use of microorganisms has increased in recent years due to their specificity to target species while not harming non-target organisms. This study aimed to evaluate optimal conditions to assess the effects of microbial plant protection products on bee species according to currently available test protocols. Some of the most commonly used microorganisms for plant protection, Bacillus thuringiensis subspecies aizawai (B. t. a. ABTS 1857) and Beauveria bassiana (B. b. ATCC 74040) were tested on Apis mellifera, Bombus terrestris, and Osmia bicornis at different temperatures (18, 26, 33 °C) under laboratory conditions.

Results
Exposure to the product containing B. t. a. ABTS 1857 resulted in higher mortality compared to B. b. ATCC 74040 in all tested bee species. A temperature-dependent effect towards higher mortality at higher temperatures of 26 °C or 33 °C was observed in O. bicornis exposed to both microorganisms. A. mellifera showed variable responses, but for B. terrestris there was mostly no effect of temperature when exposed to microorganisms in high concentrations. However, temperature affected longevity of bee species in the non-exposed control group. A. mellifera mortality increased with decreasing temperatures, while B. terrestris and O. bicornis mortality increased with increasing temperatures. A test duration of 15 or 20 days was found to be suitable for testing these microorganisms.

Conclusion
In conclusion, 26 °C should be considered the worst-case scenario for testing B. bassiana on all tested bee species. For testing B. thuringiensis, a temperature of 33 °C is recommended for A. mellifera, whereas B. terrestris and O. bicornis should be tested at 26 °C.
Interfering antibodies may contribute to elevated d-dimer: a case report
Authors: Zilstorff Dorte B. , Hermann Thomas Steffen , Rasmussen Christine , Husum Dorte , Nielsen Jørn Dalsgaard , Wewer Albrechtsen Nicolai J. 
Published: September 2024

Abstract
Background
Plasma levels of d-dimer are elevated in patients with thromboembolisms. Here we investigated the existence of interfering antibodies as a potential cause for elevated d-dimer levels.

Case presentation
A 42-year-old white Caucasian woman with a prior history of pulmonary embolism during her first pregnancy (treated with heparin therapy for 6 weeks postnatally) and hypothyroidism had a persistent elevated d-dimer without any clinical or ultrasound-based signs of thromboembolic conditions during her second pregnancy. We obtained informed consent and plasma was obtained from the patient. d-dimer levels were measured using two different assays. We also tested for the presence of rheumatoid factor, performed dilution series, and finally used an antibody depletion strategy. The two d-dimer assays performed similarly. Using our antibody depletion technique, we observed that ~ 1/3 of the increased plasma levels of d-dimer may be attributed to interfering antibodies.

Conclusions
Our results identify interfering antibodies as a potential contributor to an increased d-dimer in this patient. Our case highlights the potential of heterophilic interference for increased d-dimer and provides a procedure to determine this analytically.
Spatiotemporal dynamics of irrigated cropland water use efficiency and driving factors in northwest China’s Hexi Corridor
Authors: Du Dandan , Dong Bo , Zhang Rui , Cui Shiai , Chen Guangrong , Du Fengfeng 
Published: September 2024

Abstract
Background
Agricultural irrigation is an important practice to safeguard crops against drought and enhance grain yield in arid regions. The Hexi Corridor, known as a classic arid region, faces significant pressure on agricultural production and food security due to the scarcity of water resources. There is an urgent need to investigate agricultural water use of the irrigated regions. Water use efficiency (WUE), defined as the ratio of gross primary productivity (GPP) to actual evapotranspiration (ET), serves as a valuable indicator linking carbon assimilation and water loss. It enables the quantification of areas where water can be utilized more effectively. However, the long-term spatiotemporal dynamics of WUE and driving mechanism in the irrigated areas of the Hexi Corridor remain unclear.

Results
This study used GPP calculated by a light use efficiency model (EF-LUE), ET estimated by an ETMonitor model and irrigated cropland maps across China (IrriMap_CN) to examine the spatiotemporal dynamics of irrigated cropland WUE and its controlling factors in the Hexi Corridor from 2001 to 2018. The results are as following: (1) The average annual WUE was approximately 1.34 ± 0.38 g C kg−1 H2O yr−1, with an increasing trend of 0.012 g C kg−1 H2O yr−1, and faster growth observed during 2011–2018 compared to 2001–2010. (2) The contribution of GPP to WUE trends and WUE interannual variability (IAV) was greater than that of ET. (3) The dominant climatic factors of WUE IAV in the Hexi Corridor were SPEI, precipitation, and soil moisture. (4) The standardized Structural Equation Model (SEM), incorporating the relationship between WUE and factors such as water, energy, NDVI, and water-saving irrigation, explained 81% of the variation in irrigated cropland WUE. Here, biological factors (GPP and NDVI) were the primary factors influencing WUE variability, and water-saving irrigation had a stronger indirect effect than climate factors (water and energy) on variation in WUE.

Conclusions
Our findings offer valuable theoretical insights into the mechanisms governing the interaction between the carbon and water of irrigated cropland, guiding the management of water resources and land in agricultural practices within the Hexi Corridor.
Normalizing fentanyl: interpreting the perceived ‘risk’ of correctional officer work
Authors: Ricciardelli Rosemary , Johnston Matthew S. , Foley Gillian 
Published: September 2024

Abstract
Background
Scholarship on how fentanyl affects the complexities of correctional settings is limited in Canada, as scholars have focused on the prevalence of opioid use and overdose in prisons, as well as community treatment and access following release. Fentanyl constitutes a continuing challenge both in prisons and broader society.

Results
The current qualitative, interview-based empirical study examines how fentanyl is interpreted by correctional officers (COs, n = 99) across federal prisons in Canada, some of whom have worked in institutions with a high presence of fentanyl, while others have less exposure to the drug. We found that while many COs had responded to an overdose during their first or second year on the job, most COs who had did not perceive the event to be psychologically traumatic nor were concerned about the presence and availability fentanyl in their work environment, or they were indifferent. Yet this finding competes with the 41.4% of officers who did express concern about the presence of fentanyl – suggesting both a “normalization” of fentanyl as a workplace hazard as well as an underpinning social concern.

Conclusions
We discuss the implications of these complicated findings in relation to reducing workplace stressors and countering misinformation that, in addition to other potential occupational factors, may be responsible for the concerns of COs tied to the presence of fentanyl.
Evaluation of an automated far ultraviolet-C light technology for decontamination of surfaces and aerosolized viruses in bathrooms
Authors: Kaple Claire E. , Memic Samir , Cadnum Jennifer L. , Donskey Curtis J. 
Published: September 2024

Abstract
Background
Aerosols generated during toilet flushing are a potential source for transmission of viral and bacterial pathogens in bathrooms. However, manual decontamination of bathrooms after each use is not feasible.

Methods
We tested the efficacy of a wall-mounted far ultraviolet-C (UV-C) light technology that only delivers far UV-C when people are not present for decontamination of surfaces and aerosolized viral particles in an unoccupied hospital bathroom. A quantitative disk carrier test method was used to test efficacy against organisms on steel disk carriers placed in 9 sites in the bathroom with an exposure time of 45 min and 2 h; Clostridioides difficile spores were also exposed for 24 h. Efficacy against aerosolized bacteriophage MS2 was tested with a 45-minute exposure.

Results
The far UV-C technology reduced methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Candida auris, and bacteriophage MS2 on steel disk carriers by ≥ 1.2 log10 (range, 1.2 to 4.2 log10) at all test sites after 2 h of exposure. The technology reduced C. difficile spores by < 1 log10 after 2 h exposure, but 4 of 9 test locations had ≥ 2 log10 reductions after 24 h exposure. Aerosolized bacteriophage MS2 was reduced by 4 log10 plaque-forming units in 45 min.

Conclusions
The far UV-C light technology could potentially be useful for automated decontamination of air and surfaces in bathrooms in healthcare and community settings.
Effectiveness of facial anthropomorphism design for improving multimedia learning outcomes: systematic review and meta-analysis
Authors: Kaifeng Liu , Pengbo Su 
Published: September 2024

AbstractA systematic review and meta-analysis were conducted to examine the effectiveness of facial anthropomorphism of learning material design in improving learning and other relevant outcomes. We searched Web of Science, PsycInfo, and PsycArticle for studies published before February 2023. Learning outcomes included transfer, retention, and comprehension. Other relevant outcomes included affective-motivational, effort, and experience outcomes. Outcomes that were reported in at least five independent experiments were meta-analyzed; otherwise, a narrative synthesis was performed. Subgroup analysis by participants’ age and material type was employed for learning outcomes. A total of 33 independent experiments from 13 research articles were identified and analyzed. For learning outcomes, facial anthropomorphism yielded significant improvements in transfer (standardized mean difference [SMD] 0.28, 95% CI 0.15 to 0.40, p < 0.001), retention (SMD 0.31, 95% CI 0.14 to 0.48, p < 0.001), and comprehension (SMD 0.46, 95% CI 0.27 to 0.64, p < 0.001). Anthropomorphism yielded stronger effect in retention among juvenile students and for static learning materials. Additionally, anthropomorphism design achieved significantly positive effects in positive affect, intrinsic motivation, intrinsic motivation change, perceived difficulty, intrinsic cognitive load, germane cognitive load, perceived learning outcome, aesthetics, and enjoyment. Nineteen outcomes were narratively analyzed and mixed results were found. Facial anthropomorphism design of multimedia learning materials can induce positive emotions in learners and improve their intrinsic motivation that in turn facilitates learners’ transfer, retention, and comprehension performance. The study provides valuable insights that can guide educators and multimedia designers in applying facial anthropomorphism with learning materials to facilitate learning outcomes.
Cellular localization of a variant RAPGEF5 protein associated with idiopathic epilepsy risk in the Belgian shepherd
Authors: Cayabyab Dawn D. , Belanger Janelle M. , Xu Claudia , Maga Elizabeth A. , Oberbauer Anita M. 
Published: September 2024

AbstractThe Wnt signaling pathway is critical for normal embryonic development. Disruptions in the Wnt signaling pathway have been linked to neurological disorders. The RAPGEF5 protein is a partner in Wnt signaling and a RAPGEF5 3-bp insertion is associated with increased risk for idiopathic epilepsy in the Belgian shepherd dog. The 3-bp insertion risk variant introduces an alanine residue predicted to disrupt the protein. Wildtype and the risk variant RAPGEF5 cDNAs were cloned into green fluorescent protein (GFP) expression vectors and transfected into canine kidney cells. The cellular localization of each GFP-labeled RAPGEF5 protein was assessed. Variant RAPGEF5 protein was altered in its localization from that of the wildtype protein and rather than localized to the nucleus and cytoplasm as seen for the wildtype, it was predominantly found in the cytoplasm. Belgian shepherds with the risk variant for RAPGEF5 may have altered Wnt signaling due to modified intracellular localization which in turn could thereby contribute to the expression of idiopathic epilepsy.
Not trench-parallel but trench-normal source fault of the 1994 Hokkaido Toho-oki earthquake as revealed by the aftershock relocation using HypoDD
Authors: Katsumata Kei 
Published: September 2024

AbstractIn the southwestern area of the Kurile Islands subduction zone, three large earthquakes including the Mw8.2 1969 and the Mw8.3 1994 Hokkaido Toho-oki earthquakes and the Mw7.8 1975 tsunami earthquake occurred in almost the same location. The three main shocks and their aftershocks were re-determined simultaneously using a double-difference earthquake location method, HypoDD. As a result, the 1969 and the 1975 main shocks and their aftershocks were concentrated near the upper surface of the subducting Pacific plate, indicating that both events were plate boundary megathrust earthquakes as shown by previous studies. On the other hand, the 1994 main shock and its aftershocks were distributed within the Pacific plate indicating that the 1994 event was an intraslab event as reported by previous studies. The result that interplate earthquakes and intraslab earthquakes could be appropriately distinguished is strong evidence that the accuracy of hypocenter determination is sufficiently high. The centroid moment tensor solution of the 1994 main shock has two nodal planes which are parallel or normal to the Kurile Trench. According to the high-resolution hypocenter distribution obtained in the present study, the aftershocks appear to locate on the nodal plane normal to the trench, suggesting that the source fault ruptured by the 1994 main shock was not parallel but normal to the Kurile Trench. Moreover, we found that the Coulomb failure stress change (ΔCFS) produced by the trench-normal fault plane is more likely to trigger the largest aftershock than ΔCFS produced by the trench-parallel fault plane.
Graphical abstract