bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond annual metrics: Linking seasonal population dynamics to vertical oyster reef growth
Authors: Pfennings Kai , Hoffmann Tom K. , Hitzegrad Jan , Paul Maike , Goseberg Nils , Wehrmann Achim 
Published: September 2024

AbstractOysters are ecosystem engineering species building reef‐like biogenic structures in temperate shallow water environments, serving as biodiversity hotspots. Recently, also their ecosystem services such as fish nursery, pollutants sink and self‐sustaining coastal protection mechanisms came into a research focus. In light of accelerated sea level rise and increasing environmental dynamics, a determination of vertical growth rates of these biosedimentary structures is paramount in assessing their resilience. This study embarked on a comprehensive survey of seasonal vertical reef growth rates using terrestrial laser scanning and related population dynamics of two intertidal reefs built by the non‐native oyster Magallana gigas in the Wadden Sea. We quantified median reef growth at 19.8 mm yr−1 for the Kaiserbalje reef and 17.5 mm yr−1 for the Nordland reef. Additionally, we tested the hypothesis that the seasonal variations in reef growth rates correspond to the local population dynamics, mainly the parameters of shell length and abundance which mirror delayed effects from previous spawning events. Shell growth rates were 0.03–0.06 mm d−1 in winter and 0.10–0.16 mm d−1 in summer, mean oyster abundance from autumn 2019 to spring 2022 was 627 ± 43 ind. m−2 and 338 ± 87 ind. m−2 at the Kaiserbalje and Nordland reefs respectively. Minor reef growth in the topmost reef area reflects an emerging equilibrium of the vertical reef position to actual sea level. Our findings are in accordance with growth of natural Crassostrea virginica reefs on the US East Coast, indicating potential resilience to actual and predicted sea level rise scenarios. Moreover, understanding local hydro‐morphodynamic feedback linked to sea level rise will be vital in predicting the three‐dimensional stability of these biosedimentary structures and habitats.
Harnessing Oxoammonium Salts for Oxidations in Organic Synthesis and Catalysis: Origins and Applications
Authors: Wang Yongtao , Wen Zeyu , Liu Jiaxin , Sun Wenjing , Sun Wanqi , Hu Qixuan , Li Haoran 
Published: September 2024

AbstractThe oxoammonium cation has been identified as the true oxidant intermediate in many aerobic oxidations promoted by long‐lived nitroxide radicals. Various oxoammonium salts have been synthesized and utilized to perform these oxidation reactions. In addition to alcohol dehydrogenation and oxidative coupling reactions, new types of reactions involving oxoammonium salts have recently been reported. This concept aims to discuss these oxidations from the perspective of reaction mechanisms, with a focus on progress made since 2019. Beyond the electron transfer route for synthesizing oxoammonium salts, four types of reaction mechanisms are included.
A novel solar radiation forecasting model based on time series imaging and bidirectional long short‐term memory network
Authors: He Zhaoshuang , Zhang Xue , Li Min , Wang Shaoquan , Xiao Gongwei 
Published: September 2024

AbstractThe instability of solar energy is the biggest challenge to its successful integration with modern power grids, and accurate prediction of long‐term solar radiation can effectively solve this problem. In this study, we proposed a novel long‐term solar radiation prediction model based on time series imaging and bidirectional long short‐term memory network. First, inspired by the computer vision algorithm, the recursive graph algorithm is used to transform the one‐dimensional time series into two‐dimensional images, and then convolutional neural network is used to extract the features from the images, thus, the deeper features in the original solar radiation data can be mined. Second, to solve the problem of low accuracy of long‐term solar radiation prediction, a hybrid model BiLSTM‐Transformer is used to predict long‐term solar radiation. The hybrid prediction model can capture the long‐term dependencies, thereby further improving the accuracy of the prediction model. The experimental results show that the hybrid model proposed in this study is superior to other single models and hybrid models in long‐term solar radiation prediction accuracy. The accuracy and stability of the hybrid model are verified by many tests.
Quantifying Effects and Ingestion of Several Pristine Microplastics in Two Early Life Stages of Freshwater Mussels
Authors: Kudla Yaryna M. , Ijzerman Moira M. , Bennett C. James , Gillis Patricia L. , Kidd Karen A. , Prosser Ryan S. 
Published: September 2024

Abstract
Microplastics have been found in freshwater systems, and in turn have been detected in freshwater bivalves. However, there is limited research that defines the toxicity of microplastics to native freshwater bivalves that have long been imperiled in North America. Our objective was to determine whether a suite of pristine microplastics has an adverse effect on two early life stages of unionid freshwater mussels. Glochidia of Lampsilis fasciola (a Canadian species at risk) and Lampsilis siliquoidea (widespread across Canada) were individually exposed to spheres of polystyrene (6 and 90 μm), polyethylene (28, 90, and 1000 μm), and cellulose acetate (1000 μm), as well as fibers of polyethylene terephthalate (60 μm). After 24 h, there was no significant decrease in glochidia viability in either species. Juvenile L. siliquoidea mussels were also exposed to spheres of polystyrene (6 and 90 μm) and polyethylene (28 μm), and fibers of polyethylene terephthalate (60 μm) in individual 28-day subchronic tests followed by a 7-day depuration period. Burial was assessed weekly, and ingestion of each microplastic was compared in nondepurated and depurated mussels. There was no sustained effect on juvenile burial with any microplastic tested. Ingestion of microplastics was concentration dependent, and depuration occurred for all particles and size ranges tested. The results suggest that pristine microplastics were not acutely toxic to the early life stages of these freshwater mussels, but that the energetic costs associated with particle uptake and depuration, which were not measured in our study, may have an impact on fitness that warrants further investigation. In addition, testing with other shapes and polymers of microplastics typically detected in the environment is recommended. Environ Toxicol Chem 2024;43:2557–2568. © 2024 The Author(s). Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Enhancing high‐temperature stability of limonene‐loaded nanostructured lipid carriers with various solid lipids
Authors: Feng Simin , Tian Yitong , Sheng Jialu , Yu Jiahao , Lin Yang , Hileuskaya Kseniya , Kraskouski Aliaksandr , Li Huiliang , Lin Zhihong , Shao Ping 
Published: September 2024

AbstractIn this research, nanostructured lipid carriers (NLCs) loaded with limonene were developed using various solid lipids. The impact of high temperatures on the characteristics of NLCs was investigated. NLCs exhibited zeta potential values exceeding |30| mV, indicating excellent homogeneity and stability. Increasing the carbon chain length of monoglycerides from C15 to C21 resulted in a corresponding increase in particle size of NLCs from 219.1 ± 1.1 to 243.3 ± 0.9 nm. However, the particle size remained relatively constant with an increase in the number of solid lipid carbon chains. Encapsulation efficiency of limonene increased from 66.0 ± 0.7% to 86.2 ± 0.8% with an increase in the number of solid lipid carbon chains. The result showed that more ester bonds facilitated the dissolution of the target and enhanced the interaction forces between solid lipids and the target. X‐ray diffraction, Fourier transform‐infra‐red spectroscopy and differential scanning calorimetry analyses confirmed effective encapsulation of limonene in NLCs, resulting in good stability. NLCs prepared from various solid lipids exhibited varying properties. Glycerol triglyceride demonstrated superior stability and homogeneity of nanoparticles under high‐temperature conditions compared to other solid lipids. This study provides enhancing the thermal stability of limonene‐loaded NLCs and proposes a novel approach for their practical application.
Comprehensive Analysis of Juvenile Nasopharyngeal Angiofibromas via Whole‐Exome Sequencing
Authors: Kumari Kiran , Afroj Shariya , Madhry Deeksha , Verma Yash , Kairo Arvind K. , Thakar Alok , Sikka Kapil , Verma Hitesh , Verma Bhupendra 
Published: September 2024

ABSTRACTIntroductionThe molecular basis and mechanisms of juvenile nasopharyngeal angiofibromas (JNA) pathogenesis are still unknown. Despite being a rare and benign neoplasm, JNA is a locally aggressive and potentially destructive head and neck neoplasm, typically found in young males. The advancement of genome technologies and analytical tools has provided an unparalleled opportunity to explore the intricacy of JNA. The present study provides the first evidence of the involvement of Y‐chromosome genes in JNA.MethodsA total of 13 JNA patients at an advanced disease stage and five age‐matched male controls were registered for this study. Whole‐exome sequencing (WES) analysis was conducted followed by functional analysis to understand the molecular mechanism of the JNA.ResultsWES analysis revealed a high prevalence of mutations in 14 genes within the protein‐coding, male‐specific region of the Y‐chromosome of young males (mean age: 13.8 ± 2.4) with JNA. These mutations, occurring at 28 distinct positions, were characterized as moderate to high impact and were prevalent in nine JNA patients but not in the control group. The most frequently mutated genes were USP9Y and UTY, followed by KDM5D, DDX3Y, and TSPY4. The expression of USP9Y, UTY, and DDX3Y was found to be co‐modulated, implying their coordinated regulation as a complex. Furthermore, somatic mutations were detected in genes previously linked to JNA.ConclusionThe wide array of genetic mutations in the Y‐chromosome male‐specific region, along with the somatic alterations identified in JNA, provides novel insights into JNA pathophysiology.
Energy‐efficient channel selection algorithm with reduced collision probability in cognitive radio networks
Authors: Srivastava Anushree , Pal Raghavendra , Prakash Arun , Tripathi Rajeev , Gupta Nishu , Alkhayyat Ahmed 
Published: September 2024

AbstractThe growing demand for radio spectrum, driven by widespread communication devices, has led to spectrum congestion. Cognitive radio networks (CRNs) offer a solution by allowing secondary users (SUs) to access primary users' (PUs) channels without causing interference. This paper presents an energy‐efficient channel selection algorithm aimed at reducing collision probability and energy consumption during spectrum sensing. A prediction‐based model forecasts PU channel availability, enabling selective sensing. The results show a significant reduction in energy consumption, with the proposed method consuming 57.9% energy compared to 63.7% for a recent existing method. The proposed approach enhances spectrum management in next‐generation wireless systems by minimizing interference and optimizing energy use.
Electrospun poly(ε‐caprolactone)/poly(glycerol sebacate) aligned fibers fabricated with benign solvents for tendon tissue engineering
Authors: Iorio Francesco , El Khatib Mohammad , Wöltinger Natalie , Turriani Maura , Di Giacinto Oriana , Mauro Annunziata , Russo Valentina , Barboni Barbara , Boccaccini Aldo R. 
Published: September 2024

AbstractThe electrospinning technique is a commonly employed approach to fabricate fibers intended for various tissue engineering applications. The aim of this study is to develop a novel strategy for tendon repair through the use of aligned poly(ε‐caprolactone) (PCL) and poly(glycerol sebacate) (PGS) fibers fabricated in benign solvents, and further explore the potential application of PGS in tendon tissue engineering (TTE). The fibers were characterized for their morphological and physicochemical properties; amniotic epithelial stem cells (AECs) were used to assess the fibers teno‐inductive and immunomodulatory potential due to their ability to teno‐differentiate undergoing first a stepwise epithelial to mesenchymal transition, and due to their documented therapeutic role in tendon regeneration. The addition of PGS to PCL improved the spinnability of the polymer solution, as well as the uniformity and directionality of the so‐obtained fibers. The mechanical properties were in the range of most TTE applications, specifically in the case of PCL/PGS 4:1 and 2:1 ratios. Compared to PCL alone, the same ratios also allowed a better AECs infiltration and growth over 7 days of culture, and triggered the activation of tendon‐related genes (SCX, COL1, TNMD) and the expression of tenomodulin (TNMD) at the protein level. Concerning the immunomodulatory properties, both PCL and PCL/PGS fibers negatively affected the immunomodulatory profile of AECs, up‐regulating both anti‐inflammatory (IL‐10) and pro‐inflammatory (IL‐12) cytokines over 7 days of culture. Overall, PCL/PGS 2:1 fibers fabricated with benign solvents proved to be the most suitable composition for TTE application based on their topographical cues, mechanical properties, biocompatibility, and teno‐inductive properties.
Finite element analysis part 2 of 2: Glenohumeral bone stress distribution depends on implant configuration for anatomic and reverse stemless shoulder implants
Authors: Housset Victor , Srikumaran Umasuthan , Daudet Jean‐Marie , Fradet Léo , Bianco Rohan‐Jean , Nourissat Geoffroy 
Published: September 2024

AbstractPurposeOur purpose was to quantify stresses in the bone surrounding stemless implants in various configurations.MethodsA detailed finite element model of the glenohumeral joint was used to simulate abduction kinematics before and after arthroplasty and to measure bone stresses around the implants. Two digital patients were simulated: one healthy and one with supraspinatus muscle impairment (deficiency). Two anatomic total shoulder arthroplasty (TSA) configurations were placed in a 135° cutting plane. Two reverse shoulder arthroplasty (RSA) configurations with cutting angles of 135° and 145° were simulated with asymmetrical and symmetrical polyethylene cups, respectively, to obtain humeral neck‐shaft angles of 145°.ResultsCompared with preoperative models, TSA preserved and RSA restored abduction kinematics. The bone mechanical stresses were located mainly around the central stud of the TSA and were more peripheral to the RSA humeral components. The RSA configuration with the 145° cutting angle and symmetrical cup generated the lowest maximal bone stress and bone volume involvement. Stresses in the scapular cortical bone were highest in the supraspinatus fossa for TSA and the crest of the acromion for RSA.ConclusionEarly stability and glenohumeral bone stress change with implant configuration and should not be extrapolated from anatomic clinical data to reverse configurations.Level of EvidenceDiagnostic tests or criteria; Level IV.
Evaluation of the biodegradability of hazardous industrial solid waste: Study of key parameters
Authors: Auset M. , Margarit L. , Cuadros J. , Fernández‐Ruano L. , Claramunt M. , Mundet X. 
Published: September 2024

AbstractThe biological stability of solid waste is one of the main problems related to the environmental impact of landfills and their long‐term emission potential. Current European legislation (European Landfill Directive, EC/99/31) introduced the need to reduce biodegradable organic compounds deposited in landfills; however, it set neither official parameters nor methods to define the stability of such a waste. In Spain, biodegradability is generally evaluated using the biological oxygen demand/chemical oxygen demand (BOD5/COD) ratio, measuring it on the leachate, thus not considering the non‐soluble fraction and therefore creating false negatives. To solve this problem, the biodegradability of hazardous industrial waste has been determined by measuring its respirometric activity (AT4). Our results show that the measure of the AT4 is independent of the enrichment with a microbial inoculum, and a sample size no higher than 20 g could be a reasonable value for a sensitive biodegradability determination. The highest respirometric index is obtained in waste with pH values between 6.5 and 10.5. Furthermore, respirometric biodegradability values are independent of traditional parameters of organic matter characterization such as BOD5/COD ratio, volatile content, and total and dissolved organic carbon. Consequently, the AT4 parameter provides new information on the composition and stability of organic matter in hazardous industrial waste. Its incorporation into pre‐disposal waste characterization protocols allows to identify waste that exceeds recommended biodegradability thresholds. This approach ensures that only waste meeting specified biodegradability standards is deposited, avoiding landfill emissions and related environmental impacts, and thereby improving the overall effectiveness and sustainability of waste management practices.
High rate of uncontrolled hypertension among adults receiving integrated HIV and hypertension care with aligned multi‐month dispensing in Malawi: results from a cross‐sectional survey and retrospective chart review
Authors: Whitehead Hannah S. , Phiri Khumbo , Kalande Pericles , van Oosterhout Joep J. , Talama George , Phiri Sam , Moucheraud Corrina , Moses Agnes , Hoffman Risa M. 
Published: September 2024

AbstractIntroductionPeople living with HIV have high rates of hypertension. Integrated HIV and hypertension care with aligned multi‐month dispensing of medications (MMD) could decrease the burden of care for individuals and health systems. We sought to describe hypertension control and evaluate its association with different durations of MMD among Malawian adults receiving integrated care with aligned dispensing of antiretroviral therapy (ART) and antihypertensive medication.MethodsWe conducted a cross‐sectional survey and retrospective chart review of adults (≥18 years) receiving integrated HIV and hypertension care on medications for both conditions for at least 1 year, with aligned MMD at seven clinics in Malawi. Data were collected from July 2021 to April 2022 and included socio‐demographics, clinical characteristics, antihypertensive medications and up to the three most recent blood pressure measurements. Bivariate analyses were used to characterize associations with hypertension control. Uncontrolled hypertension was defined as ≥2 measurements ≥140 and/or ≥90 mmHg. Chart reviews were conducted for a random subset of participants with uncontrolled hypertension to describe antihypertensive medication adjustments in the prior year.ResultsWe surveyed 459 adults receiving integrated care with aligned dispensing (58% female; median age 54 years). Individuals most commonly received a 3‐month aligned dispensing of ART and antihypertensive medications (63%), followed by every 6 months (16%) and every 4 months (15%). Hypertension control was assessed in 359 respondents, of whom only 23% had controlled hypertension; 90% of individuals in this group reported high adherence to blood pressure medications (0−1 missed days/week). Control was more common among those with longer aligned medication dispensing intervals (20% among those with 1‐ to 3‐month dispensing vs. 28% with 4‐month dispensing vs. 40% with 6‐month dispensing, p = 0.011). Chart reviews were conducted for 147 individuals with uncontrolled hypertension. Most had high self‐reported adherence to blood pressure medications (89% missing 0−1 days/week); however, only 10% had their antihypertensive medication regimen changed in the prior year.ConclusionsUncontrolled hypertension was common among Malawian adults receiving integrated care with aligned MMD and was associated with shorter refill intervals and few antihypertensive medication escalations. Integrated care with aligned MMD is promising, but further work is needed to understand how to optimize hypertension outcomes.
A hybrid repair strategy for full‐thickness cartilage defects: Long‐term experimental study in eight horses
Authors: Fugazzola Maria C. , De Ruijter Mylène , Veraa Stefanie , Plomp Saskia , van Buul Ward , Hermsen Gied , van Weeren René 
Published: September 2024

AbstractThe objective of this study was to evaluate a non‐resorbable implant for the focal repair of chondral defects in eight adult horses with 12‐month follow‐up. The bi‐layered construct composed of a polycarbonate‐urethane‐urea biomaterial which was printed in 3D fashion onto a bone anchor was implanted into surgically created osteochondral defects into the femoropatellar joints of eight horses. The analysis of post‐mortem outcomes were compared to defects treated with microfracture in the same animal on the contralateral femoropatellar jointfemoropatellar joint. The overall macroscopic scoring after 12 months yielded higher scores in the OCI‐treated stifles compared to MF treatment (p = 0.09) with better quality and filling of the defect. Histology revealed good anchorage of repair tissue growing into the 3D structure of the implant and histopathology scoring for adjacent native cartilage showed no difference between groups. MRI and micro‐CT showed overall less sclerotic reactions in the surrounding bone in the implant group and no foreign body reaction was detected. Biomechanical analysis of the repair tissue revealed a significantly higher peak modulus (p < 0.05) in the implant group (0.74 ± 0.45) compared to the microfracture control group (0.15 ± 0.11). Dynamic loading yielded higher values for the repair tissue overgrowing the implant group (0.23 ± 0.17) compared to the microfracture control (0.06 ± 0.06) (p < 0.05). The bi‐layered osteochondral implant provided a safe implant for focal repair of full‐thickness osteochondral defects, as no adverse reaction was seen within the joints and the level of degeneration of adjacent cartilage to the repair site was not different compared to that seen in defects treated with microfracture after 12 months.
A Novel Incident Circular Polarized Light Raman Optical Activity (ICP‐ROA) Spectrometer With Advanced Polarization Control
Authors: Hofmann Klaus , Martin Luisa , Fischer Ingo 
Published: September 2024

ABSTRACTThe design and setup of a novel and simple backscatter Raman optical activity (ROA) spectrometer with incident light circular polarization (ICP) is presented, constructed from commercially available components. Incident light polarization is controlled using a combination of waveplates, compensating for unwanted birefringence and beam offsets. Realignment of the spectra in post‐processing reduced artifacts caused by spatial offsets. Spurious signals from achiral solvents like toluene and water are almost completely removed. The setup was validated by measuring references samples, including α‐pinene, carvone, and glucose in aqueous solution. The spectra show very good agreement with previously published results.