bluuebunny/crossref_metadata_2025_split huggingface dataset:
An evaluation of delivery of the parent Preschool Life Skills program via telehealth
Authors: Lee Helena , Gunning Ciara , Leow Jolyene , Holloway Jennifer 
Published: September 2024

AbstractUsing telehealth technology to deliver parent training in evidence‐based intervention has been suggested to increase the accessibility of such interventions and improve skill acquisition and generalization. Within behavior analysis, global restrictions in response to the COVID‐19 pandemic highlighted the need for the development of telehealth supports for families. The current research examined the online delivery of a parent‐mediated implementation of the Preschool Life Skills program (PLS). Four parents completed the parent PLS program with their typically developing children (aged 3–5 years) via weekly videoconferencing sessions. A multiple‐probe experimental design was employed to assess the effect of the intervention on children's preschool life skills and challenging behavior. Parental embedding of PLS strategies during daily activities was also evaluated. The results demonstrated increases in children's preschool life skills, decreases in challenging behavior, and evidence of parent acquisition and use of PLS strategies.
Comparative Study Between Variable Flip Angle and Modified Look–Locker Inversion Recovery for Evaluating Renal Interstitial Fibrosis
Authors: Hua Chenchen , Zhuang Yi , Wang Miaoyan , Cai Ting , Xu Bin , Hao Shaowei , Fang Xiangming , Wang Liang , Zhou Leting 
Published: September 2024

BackgroundVariable flip angle (VFA) and modified Look–Locker inversion recovery (MOLLI) are frequently used for noninvasive evaluation of renal interstitial fibrosis (IF) in chronic kidney disease (CKD). However, controversy remains over which method is preferred.PurposeTo compare the diagnostic efficacy of VFA and MOLLI for T1 mapping in evaluating renal IF.Study TypeProspective.SubjectsFifty‐one participants with CKD (CKD stage 1–5, 35 males) and 18 healthy volunteers (eight males).Field Strength/Sequence3.0 T, three‐dimensional gradient echo sequence for B1+ VFA, and two‐dimensional gradient echo sequence for MOLLI.AssessmentImage quality was assessed on a five‐point scale. Cortex and medulla T1 values (cT1 and mT1), corticomedullary T1 value difference (ΔT1, medulla − cortex), and corticomedullary T1 value ratio (ratio T1, cortex:medulla) were compared between VFA and MOLLI as well as between IF grade (0–4) based on biopsy.Statistical TestsIntraclass correlation coefficient, Bland–Altman analysis, analysis of variance, Kruskal–Wallis test, correlation analysis, and receiver operating characteristics analysis with the area under the curve (AUC). P‐value <0.05 was considered significant.ResultsMOLLI provided significantly better image quality compared to VFA. cT1 and mT1 values significantly differed between VFA and MOLLI (cT1‐VFA: 1771.4 ± 139.4 msec vs. cT1‐MOLLI: 1729.9 ± 132.1 msec; mT1‐VFA: 2076.0 [interquartile range (IQR): 2045.9–2129.9] msec vs. mT1‐MOLLI: 2039.2 [IQR: 1997.8–2071.6] msec). ΔT1 and ratio T1 values were not different between VFA and MOLLI (ΔT1: 300.8 ± 71.4 vs. 306.0 ± 78.4, respectively, P = 0.33 and ratio T1: 0.85 ± 0.038 vs. 0.85 ± 0.041, respectively, P = 0.064). No difference was observed between T1 variables and T1 mapping methods in diagnosing IF.Data ConclusionΔT1 and ratio T1 were not different between VFA and MOLLI. Both VFA and MOLLI are effective for noninvasive assessment of renal IF.Level of Evidence2Technical EfficacyStage 2
Secondary matrix‐associated autologous chondrocyte implantation after failed cartilage repair shows superior results when combined with autologous bone grafting: Findings from the German Cartilage Registry (KnorpelRegister DGOU)
Authors: Weishorn Johannes , Niemeyer Philipp , Angele Peter , Spahn Gunther , Tischer Thomas , Renkawitz Tobias , Bangert Yannic 
Published: September 2024

AbstractPurposeThe aim of this study was to evaluate whether additive autologous bone grafting (ABG) improves clinical outcome and survival in revision matrix‐associated autologous chondrocyte implantation (M‐ACI) after failed cartilage repair (CR).MethodsA retrospective, registry‐based, matched‐pair analysis was performed to compare patient‐reported outcomes and survival in secondary M‐ACI with or without additional bone grafting for focal full‐thickness cartilage defects of the knee and to compare it with those in primary M‐ACI. Patients were matched for age, sex, body mass index, defect size and localization, and number of previous CRs. The Knee Injury and Osteoarthritis Outcome Score (KOOS) was assessed over a follow‐up period of 36 months. The patient acceptable symptomatic state, the clinical response rate and the survival of the subgroups were determined.ResultsA total of 818 patients were matched. Revision M‐ACI (n = 238) with concomitant bone grafting was associated with significantly higher PRO as measured by KOOS (80.8 ± 16.8 vs. 72.0 ± 17.5, p = 0.032) and higher CRR (81.4% vs. 52.0%, p = 0.018) at 36 months compared to patients with revision M‐ACI alone. KOOS and KOOS improvement in these patients did not differ from those who underwent primary M‐ACI (p = n.s.). The combination of M‐ACI and ABG resulted in a significantly higher KOOS at 36 months than M‐ACI alone, regardless of whether bone marrow stimulation (89.6 ± 12.5 vs. 68.1 ± 17.9, p = 0.003) or ACI (82.6 ± 17.0 vs. 72.8 ± 16.0, p = 0.021) was performed before. Additional bone grafting results in equivalent survival rates at 7 years in secondary compared to primary M‐ACI (83% vs. 84%, p = n.s.).ConclusionsRegardless of the type of previous CR, additional bone grafting in secondary M‐ACI improves the clinical outcome, response rate and survival at 36 months compared to M‐ACI alone. Secondary M‐ACI with ABG had comparable clinical response and survival rates to primary M‐ACI. Therefore, subchondral bone should be treated even in cases of mild bone involvement in revision M‐ACI.Level of evidenceLevel III.
Cross‐cultural adaptation of the empowerment scale of pregnant women in China context: An integrative method of translation and linguistic validation
Authors: Liu Yanjia , Che Chong Chin , Hamdan Mukhri , Chong Mei Chan 
Published: September 2024

AbstractAimTo translate the Empowerment Scale for Pregnant Women (ESPW) into Chinese and to assess its linguistic validity.MethodsThe integrative method of the translation process, the Delphi technique, and cognitive interviews were used to implement cross‐cultural adaptation and enhance comprehensibility and linguistic validation. This study recruited 14 experts in the expert review and cognitively reviewed 15 pregnant women.ResultsThe two‐round Delphi method created agreement on cultural applicability. The results of content validity achieved good levels: The item‐level content validity index (CVI) ranged from 0.78 to 1.00, and the scale‐level content validity index, calculated using two different formulas, were 0.97 and 0.81, respectively. Kappa values ranged from 0.74 to 1.00. Pregnant women could understand most of the items and response options in the cognitive interview. The revisions to the wording were made based on suggestions from experts and pregnant women.ConclusionThe prefinal simplified Chinese ESPW was semantically and conceptually equivalent to the English version, which was well prepared for further psychometric tests in the next stage of cross‐cultural adaptation.Patient or Public ContributionThis comprehensive method successfully developed a Chinese tool to measure the empowerment of pregnant women, indicating the international applicability of this tool and the methodological scientific nature. The simplified Chinese ESPW has the potential to support the identification of empowerment levels of pregnant women and the evaluation of the effectiveness of health education and promotion programmes.
The use of bibliometrics in nursing science: Topics, data sources and contributions to research and practice
Authors: Mezquita Belén , Alfonso‐Arias Cristina , Martínez‐Jaimez Patricia , Borrego Ángel 
Published: September 2024

AbstractAimTo describe the use of bibliometrics in nursing and assess their contribution to research and practice.DesignA content analysis was conducted of topics, data sources and applications of bibliometrics in nursing research articles.MethodsThe study universe included 129 bibliometric articles on nursing retrieved from Scopus. A content analysis was performed to identify the purposes and topics of the articles, the sources employed to collect the data, the time frames covered, the amounts of records surveyed, and the features of the nursing literature analysed in bibliometric papers.ResultsNursing bibliometric research revolves around six key areas: global descriptions of the nursing literature, literature on specific nursing research topics, nursing education, nursing profession, nursing research using a certain framework or method, and nursing literature published in a country or region. Studies rely on three types of sources to retrieve the surveyed literature: bibliographic databases, sets of disciplinary journals and samples of documents. Bibliometrics can be employed to advance nursing research (identification of research gaps, establishment of research agendas, assessment of methodological approaches, etc.) and practice (identification of professional competences, categorisation of professional tasks, recognition of educational improvements, etc.), suggesting new avenues for researchers who aim to conduct further bibliometric research in the field. Further research is needed to assess the coverage of the nursing literature by new bibliographic data sources and to explore unaddressed topics such as gender imbalance in authorship.
Screening thrombin inhibitors from Yangxinshi tablets by online capillary electrophoresis‐based immobilized enzyme microreactor and molecular docking
Authors: Liu Wenping , Zhou Rui , Wen Jiake , Li Jin , Du Kunze , He Jun , Yao Yaqi , Chang Yanxu 
Published: September 2024

AbstractIntroductionYangxinshi tablet (YXST) is a effective traditional Chinese medicine in treating cardiovascular diseases such as heart failure and myocardial infarction.ObjectivesThis study aims to develop a method for screening thrombin inhibitors from YXST using an online immobilized enzyme microreactor (IMER) based on capillary electrophoresis (CE).Materials and methodsThrombin (THR) was immobilized on the capillary's inner wall using polydopamine (PDA). The chromogenic substrate S‐2238 was employed to assess thrombin (THR) activity and kinetic parameters. The stability and repeatability of the constructed thrombin‐immobilized enzyme microreactor (THR‐IMER) were evaluated over 40 runs, maintaining 85% of initial activity. The Michaelis–Menten constant (Km) for THR was determined to be 11.98 mM. The half‐maximal inhibitory concentration (IC50) and inhibition constant (Ki) for argatroban on THR were calculated. Ten compounds in YXST were screened for THR inhibitory potency using the THR‐IMER.ResultsSalvianolic acid B and caffeic acid were identified as potential THR inhibitors in YXST, with inhibition rates at 200 μg/mL of 55.06 ± 6.70% and 31.88 ± 4.79%, respectively, aligning with microplate reader assay results. Molecular docking analysis confirmed their interactions with key THR residues, verifying their inhibitory activity.ConclusionThe CE‐based THR‐IMER method was successfully developed for screening thrombin inhibitors from YXST, offering a reliable approach for identifying potential therapeutic compounds.
The CT and pathological features of intestinal inflammatory myofibroblastic tumor
Authors: Zhou Ming , Wang Zhongchao , Sun Jun 
Published: September 2024

AbstractTo explore computed tomography (CT) findings and pathological features of intestinal inflammatory myofibroblastic tumors (IMT). A retrospective review was conducted on the CT features of five patients with pathologically confirmed IMT, which were then compared with the corresponding pathological findings. The study included four female and one male patients. The tumors were located in the rectum (n = 1), small intestine (n = 2), or cecum (n = 2). One patient exhibited a cystic solid mass with exophytic growth and the solid components showed moderate enhancement. Additionally, flaky low‐density, marginal line‐like calcified shadows were observed around the lesions. Two cases presented as solid masses within the lumen of the intestinal tract, showing obvious non‐uniform enhancement along with visible enhancement shadows of small blood vessels. One patient had a metastasis. In two other cases, solid masses grew outside the lumen of the intestinal tract, demonstrating progressive and delayed enhancement on enhanced scans, as well as local nodular enhancement and ring enhancement. These two cases also exhibited focal sarcomatoid lesions, along with their respective IMTs. Histologically, these tumors mainly consist of proliferating spindle myofibroblast cells accompanied by variable infiltration by interstitial inflammatory cells, such as fibroblasts. Immunohistochemical analysis revealed positive staining for smooth muscle actin (SMA) in ~80% of the cells tested, while vimentin staining was positive in ~60% of the cells. Intestinal IMT is an extremely rare tumor with imaging features that can reflect the underlying pathological characteristics to some extent, thus aiding diagnosis.
Scheme using a finite‐volume method for local horizontal derivatives in the spectral model: The non‐hydrostatic case
Authors: Yang Jinhui , Wu Jianping , Song Junqiang , Peng Jun , Yin Fukang , Leng Hongze , Ren Kaijun , Yang Xiangrong 
Published: September 2024

AbstractIn a typical non‐hydrostatic spectral dynamic numerical weather prediction (NWP) kernel, all forecast variables are transformed between grid point and spectral spaces to compute their gradients and solve the implicit problem. This kernel requires numerous spectral transformations, which depend heavily on extensive global communication and significantly hinder parallel computing efficiency. This paper introduces an innovative non‐hydrostatic spectral kernel that incorporates a finite‐volume method within the spectral framework. We have developed a horizontal divergence (D)‐based structure equation, allowing direct computation of most prognostic variables and their horizontal gradients at grid point space. By doing so, the need for spectral transformations is substantially decreased. Our experiments demonstrate that this new approach reduces the cost of spectral transformations by up to 40%, enhancing the overall model efficiency by 15%–22%. Additionally, a series of tests confirmed the accuracy and stability of this new solver.
Explaining compliance with voluntary sustainability standards: A case study from Colombia's coffee belt
Authors: Batistic Paulo Mortara , Dietz Thomas , Börner Jan , Damm Yannic Rudá 
Published: September 2024

AbstractThis paper aims to explain producer compliance with Voluntary Sustainability Standards (VSS), instruments of private governance regarded as key to solving sustainability issues in global value chains. We employ a dataset of 194 Colombian coffee producers who are certified by one or more VSS to break down the factors leading to farmer compliance with environmental criteria linked to VSS. In total, we analyse 19 environmental criteria, derived from 10 obligations from five different sustainability standards. We expect compliance to be explained by different theoretical approaches, being either rational choice, capacity, legitimacy, or opportunity, operationalised by grouping related variables. Rational choice and legitimacy‐related drivers, as well as opportunity, show mostly positive, mild to strong effects on compliance, while capacity variables show no significant effect. We propose that a hybrid approach among theories explains coffee farmers' compliance with environmental VSS requirements, empowering policy‐makers and standard setters to adjust practices and policies accordingly.
Titania‐Cored Janus Multipods as UV‐Protective Pickering Emulsifiers for Sunscreens
Authors: Kwon Jaeyeong , Kim Minji , Kim You‐Jin , Oh Heemuk , Lee Jun Bae , Yi Gi‐Ra , Lee Hyomin 
Published: September 2024

AbstractPickering emulsifiers have gained significant interest as alternatives for conventional surfactants in various applications that includes pharmaceutics, food, homecare products, and cosmetics. However, their function is primarily focused on enhancing emulsion stability of which still remains to be resolved. Herein, Janus multipods are presented that simultaneously shield UV while offering high emulsion stability. These particles are prepared by growing multiple silicon dioxide (SiO2) nanopods using sol–gel method on a spherical titanium dioxide (TiO2) core with a thin SiO2 shell. The incorporation of high refractive index TiO2 in the core is shown to effectively shield UV while the SiO2 shell suppresses the photocatalytic activity. Moreover, by utilizing wax colloidosomes as templates, these multipod nanoparticles are further modified to exhibit Janus characteristics. This leads to strong adsorption of the Janus multipods at the oil/water emulsion interface where the multipod feature additionally reinforces the interfacial stabilization by interdigitation and interlocking of the Janus multipods to suppress detachment of the highly dense particles from the interface. As these Janus multipods offer effective UV protection as well as excellent emulsion stability, it is envisioned that they have great potential in advanced cosmetic formulations which require both enhanced sunscreen performance and better feeling in skincare products.
Injectable PLGA Microscaffolds with Laser‐Induced Enhanced Microporosity for Nucleus Pulposus Cell Delivery
Authors: Nakielski Paweł , Kosik‐Kozioł Alicja , Rinoldi Chiara , Rybak Daniel , More Namdev , Wechsler Jacob , Lehmann Tomasz P. , Głowacki Maciej , Stępak Bogusz , Rzepna Magdalena , Marinelli Martina , Lanzi Massimiliano , Seliktar Dror , Mohyeddinipour Sarah , Sheyn Dmitriy , Pierini Filippo 
Published: September 2024

AbstractIntervertebral disc (IVD) degeneration is a leading cause of lower back pain (LBP). Current treatments primarily address symptoms without halting the degenerative process. Cell transplantation offers a promising approach for early‐stage IVD degeneration, but challenges such as cell viability, retention, and harsh host environments limit its efficacy. This study aimed to compare the injectability and biocompatibility of human nucleus pulposus cells (hNPC) attached to two types of microscaffolds designed for minimally invasive delivery to IVD. Microscaffolds are developed from poly(lactic‐co‐glycolic acid) (PLGA) using electrospinning and femtosecond laser structuration. These microscaffolds are tested for their physical properties, injectability, and biocompatibility. This study evaluates cell adhesion, proliferation, and survival in vitro and ex vivo within a hydrogel‐based nucleus pulposus model. The microscaffolds demonstrate enhanced surface architecture, facilitating cell adhesion and proliferation. Laser structuration improved porosity, supporting cell attachment and extracellular matrix deposition. Injectability tests show that microscaffolds can be delivered through small‐gauge needles with minimal force, maintaining high cell viability. The findings suggest that laser‐structured PLGA microscaffolds are viable for minimally invasive cell delivery. These microscaffolds enhance cell viability and retention, offering potential improvements in the therapeutic efficiency of cell‐based treatments for discogenic LBP.
Tailoring Pseudo‐Graphitic Domain by Molybdenum Modification to Boost Sodium Storage Capacity and Durability for Hard Carbon
Authors: Zhou Yaqin , Wang Yuanlang , Fu Chunyan , Zhou Ji , Song Yijian , Lin Shangyong , Liang Shuquan , Zhou Shuang , Pan Anqiang 
Published: September 2024

AbstractHard carbon (HC) stands out as the most prospective anode for sodium‐ion batteries (SIBs) with significant potential for commercial applications. However, some long‐standing and intractable obstacles, like low first coulombic efficiency (ICE), poor rate capability, storage capacity, and cycling stability, have severely hindered the conversion process from laboratory to commercialization. The above‐mentioned issues are closely related to Na+ transfer kinetics, surface chemistry, and internal pseudo‐graphitic carbon content. Herein, constructing molybdenum‐modified hard carbon solid spheres (Mo2C/HC‐5.0), both the ion transfer kinetics, surface chemistry, and internal pseudo‐graphitic carbon content are comprehensively improved. Specifically, Mo2C/HC‐5.0 with higher pseudo‐graphitic carbon content provides a large number of active sites and a more stable layer structure, resulting in improved sodium storage capacity, rate performance, and cycling stability. Moreover, the lower defect density and specific surface area of Mo2C/HC‐5.0 further enhance ICE and sodium storage capacity. Consequently, the Mo2C/HC‐5.0 anode achieves a high capacity of 410.7 mA h g−1 and an ICE of 83.9% at 50 mA g−1. Furthermore, the material exhibits exceptional rate capability and cycling stability, maintaining a capacity of 202.8 mA h g−1 at 2 A g−1 and 214.9 mA h g−1 after 800 cycles at 1 A g−1.
Rational Linker Design for Enhanced Performance of MOF‐Derived Catalysts in Electrochemical Urea Synthesis
Authors: Zhu Xiaorong , Ge Ming , Yuan Xiaolei , Wang Yijin , Tang Yanfeng 
Published: September 2024

Abstract2D metal–organic frameworks (2D MOFs) offer promising electrocatalytic potential for urea synthesis, yet the underlying reaction mechanisms and structure‐activity relationships remain unclear. Using Cu‐BDC as a model, density functional theory (DFT) calculations to elucidate these aspects are conducted. The results reveal a novel coupling mechanism involving *NO─CO and *NO─*ONCO, emphasizing the impact of linker modifications on Cu spin states and charge distribution. Notably, Cu‐BDC‐NH2 and Cu─BDC─OH emerge as promising catalysts. Additionally, structure‐activity relationships through descriptors like d‐band center, IE ratio, and L(Cu─O), providing insights for rational catalyst design is established. These findings pave the way for optimized catalysts and sustainable urea production, opening avenues for future research and technological advancements.
An Enzyme‐Encapsulated MOF@MOF Nanocomposite for Detecting H2O2 Derived From Superoxide Anion Released by Mitochondria of HeLa Cells
Authors: Niu Jiaqi , Jin Xiaoxin , Wang Xingqi , Ren Zhenhua , Li Bingjie , Liu Xiaoqiang , Wong Danny K.Y. 
Published: September 2024

AbstractIn this work, a horseradish peroxidase (HRP)‐encapsulated metal organic framework (MOF)@MOF nanocomposite is developed for detecting H2O2 converted by dismutation of superoxide anions released from live HeLa mitochondria. Initially, an HRP‐polyacrylic acid cluster is incorporated on a mesoporous, peroxidase‐like Cu/Co‐1,4‐benzenedicarboxylate (BDC) MOF platform to avoid structural change and deactivation of HRP through its interactions with MOF metal ions. Additionally, a Cu/Co‐BDC(HRP)@1,3,5‐benzenetricarboxyate (BTC) core‐shell MOF/MOF structure, also with peroxide‐like properties, serves as a protective matrix for HRP. Then, ultrathin porous carbon shells (UPCS) are adopted to improve the electrical conductivity of the MOF@MOF. The Cu/Co‐BDC(HRP)@BTC|UPCS sensing platform exhibits two linear ranges of 0.05–1 µM and 1–1000 µM with a sensitivity of 172 mA mM−1 cm−2 and 1.63 mA mM−1 cm−2, respectively. A limit of detection of 0.057 µM, good selectivity and stability over 35 days for H2O2 detection are also achieved. After treating the mitochondrial complex with specific inhibitors, amperometric results at the sensing platform confirmed complex I and III within mitochondria as the main electron leakage sites in the electron transfer chains. Therefore, this sensing platform provides a tool that may aid in predicting and even developing treatments for some oxidative stress diseases caused by mitochondrial abnormalities.