bluuebunny/crossref_metadata_2025_split huggingface dataset:
External corporate governance and financial fraud: cognitive evaluation theory insights on agency theory prescriptions
Authors: Shi Wei , Connelly Brian L. , Hoskisson Robert E. 
Published: July 2016

Research summary:Agency theory suggests that external governance mechanisms (e.g., activist owners, the market for corporate control, securities analysts) can deter managers from acting opportunistically. Using cognitive evaluation theory, we argue that powerful expectations imposed by external governance can impinge on top managers' feelings of autonomy and crowd out their intrinsic motivation, potentially leading to financial fraud. Our findings indicate that external pressure from activist owners, the market for corporate control, and securities analysts increases managers' likelihood of financial fraud. Our study considers external governance from a top manager's perspective and questions one of agency theory's foundational tenets: that external pressure imposed on managers reduces the potential for moral hazard.Managerial summary:Many of us are familiar with stories about top managers “cooking the books” in one way or another. As a result, companies and regulatory bodies often implement strict controls to try to prevent financial fraud. However, cognitive evaluation theory describes how those external controls could actually have the opposite of their intended effect because they rob managers of their intrinsic motivation for behaving appropriately. We find this to be the case. When top managers face more stringent external control mechanisms, in the form of activist shareholders, the threat of a takeover, or zealous securities analysts, they are actually more likely to engage in financial misbehavior. Copyright © 2016 John Wiley & Sons, Ltd.
Differential effect of assisted reproductive technology and small‐for‐gestational age on fetal cardiac remodeling
Authors: Valenzuela‐Alcaraz B. , Crispi F. , Cruz‐Lemini M. , Bijnens B. , García‐Otero L. , Sitges M. , Balasch J. , Gratacós E. 
Published: July 2016

ABSTRACTObjectiveFetuses conceived by assisted reproductive technology (ART) and those that are small‐for‐gestational age (SGA) show cardiovascular remodeling in utero; however, these two conditions are often associated. We aimed to evaluate the differential effect of ART and SGA on fetal cardiac remodeling.MethodsThis was a prospective cohort study of term singleton pregnancies seen at our department between April 2011 and September 2013. The cohort was divided according to fetal growth and mode of conception into the following four groups: 102 appropriate‐for‐gestational‐age (AGA) fetuses conceived spontaneously (controls), 72 AGA fetuses conceived by ART (ART‐AGA), 31 SGA fetuses conceived by ART (ART‐SGA) and 28 SGA fetuses conceived naturally (Spont‐SGA). SGA was defined as birth weight < 10th centile. Fetal echocardiography was performed at 28–32 weeks to assess cardiac dimensions, geometry and function.ResultsART fetuses had dilated atria (mean left atrium‐to‐heart area ratio: controls, 15 ± 2.7%; ART‐AGA, 18 ± 4.1%; Spont‐SGA, 14 ± 3.7%) and more globular ventricles (left ventricular sphericity index: controls, 1.77 ± 0.2; ART‐AGA, 1.68 ± 0.2; Spont‐SGA, 1.72 ± 0.2), with normally sized hearts. In contrast, SGA fetuses had enlarged hearts (cardiothoracic ratio: controls, 24 ± 3%; ART‐AGA, 24 ± 4%; Spont‐SGA, 29 ± 6%), preserved atrial size, more globular and concentric hypertrophic ventricles (left ventricle relative wall thickness: controls, 0.48 ± 0.17; ART‐AGA, 0.54 ± 0.13; Spont‐SGA, 0.63 ± 0.23). Both ART and SGA fetuses had decreased longitudinal motion (tricuspid annular ring displacement: controls, 6.5 ± 0.8 mm; ART‐AGA, 5.5 ± 0.7 mm; Spont‐SGA, 5.9 ± 0.6 mm) and impaired relaxation (left isovolumetric relaxation time: controls, 47.0 ± 7.3 ms; ART‐AGA, 50.0 ± 7.9 ms; Spont‐SGA, 49.5 ± 9.3 ms). ART‐SGA fetuses presented a combination of features from both ART and SGA groups.ConclusionSGA and conception with ART were associated with distinct patterns of fetal cardiac remodeling, supporting the concept that they are independent causes of cardiac programming. Copyright © 2016 ISUOG. Published by John Wiley & Sons Ltd.
Classification systems in dynamic environments: an overview
Authors: Pinage Felipe Azevedo , dos Santos Eulanda Miranda , da Gama João Manuel Portela 
Published: July 2016

Data mining and machine learning algorithms can be employed to perform a variety of tasks. However, since most of these problems may depend on environments that change over time, performing classification tasks in dynamic environments has been a challenge in data mining research domain in the last decades. Currently, in the literature, the most common strategies used to detect changes are based on accuracy monitoring, which relies on previous knowledge of the data in order to identify whether or not correct classifications are provided. However, such a feedback can be infeasible in practical problems. In this work, we present a comprehensive overview of current machine learning/data mining approaches proposed to deal with dynamic environments problems. The objective is to highlight the main drawbacks and open issues, as well as future directions and problems worthy of investigation. In addition, we provide the definitions of the main terms used to represent this problem in the literature, such as concept drift and novelty detection. WIREs Data Mining Knowl Discov 2016, 6:156–166. doi: 10.1002/widm.1184This article is categorized under:

Technologies > Classification
Technologies > Machine Learning
A phase I dose-escalation study of LY2875358, a bivalent MET antibody, given as monotherapy or in combination with erlotinib or gefitinib in Japanese patients with advanced malignancies
Authors: Yoh Kiyotaka , Doi Toshihiko , Ohmatsu Hironobu , Kojima Takashi , Takahashi Hideaki , Zenke Yoshitaka , Wacheck Volker , Enatsu Sotaro , Nakamura Takashi , Turner Kellie , Uenaka Kazunori 
Published: July 2016

SummaryBackground MET is a tyrosine kinase receptor involved in the regulation of cell proliferation and migration. Reported here are the phase I dose-escalation results for LY2875358, a monoclonal antibody against MET, in Japanese patients with advanced malignancies. Methods The study comprised a 3 + 3 dose-escalation part for LY2875358 monotherapy in patients with advanced malignancies (Part A) followed by an assessment of LY2875358 in combination with erlotinib or gefitinib in patients with non-small cell lung cancer (Part B). LY2875358 was administered once every 2 weeks. The primary objective was to evaluate the safety and tolerability of LY2875358; secondary objectives included evaluation of pharmacokinetics, pharmacodynamics, and antitumor activity. Results Eleven patients received LY2875358 monotherapy at 3 dose levels (700 mg, N = 3; 1400 mg, N = 3; 2000 mg, N = 5) and 6 patients received LY2875358 2000 mg in combination with erlotinib (N = 3) or gefitinib (N = 3). No dose-limiting toxicities or serious adverse events related to LY2875358 were observed. The most frequently reported drug-related adverse events were hypoalbuminemia (2 patients) in Part A and dermatitis acneiform (4 patients) in Part B. LY2875358 area under the curve (AUC) and maximum concentration (Cmax) increased with dose over the dose range of 700 mg to 2000 mg. A best response of stable disease was achieved by 2/11 patients in Part A and 4/6 patients in Part B (disease control rate: 35 %). Conclusions LY2875358 at doses up to 2000 mg demonstrated a favorable safety and tolerability profile as monotherapy or in combination with erlotinib or gefitinib in Japanese patients with advanced malignancies.
Prevailing-frequency approximation of the coupling ray theory for electromagnetic waves or elastic S waves
Authors: Klimeš Luděk , Bulant Petr 
Published: July 2016

Abstract
The coupling–ray–theory tensor Green function for electromagnetic waves or elastic S waves is frequency dependent, and is usually calculated for many frequencies. This frequency dependence represents no problem in calculating the Green function, but may represent a great problem in storing the Green function at the nodes of dense grids, typical for applications such as the Born approximation. This paper is devoted to the approximation of the coupling–ray–theory tensor Green function, which practically eliminates this frequency dependence within a reasonably broad frequency band.
In the vicinity of a given prevailing frequency, we approximate the frequency–dependent frequency–domain coupling–ray–theory tensor Green function by two dyadic Green functions corresponding to two waves described by their travel times and amplitudes calculated for the prevailing frequency. We refer to these travel times and amplitudes as the coupling–ray–theory travel times and the coupling–ray–theory amplitudes. This “prevailing–frequency approximation” of the coupling ray theory for electromagnetic waves or elastic S waves allows us to process the coupling–ray–theory wave field in the same way as the anisotropic–ray–theory wave field. This simplification may be decisive when storing the tensor Green function at the nodes of dense grids, which is typical for applications such as the Born approximation.
We test the accuracy of the proposed prevailing–frequency approximation of the coupling ray theory numerically using elastic S waves in eight anisotropic velocity models. The additional inaccuracy introduced by the prevailing–frequency approximation is smaller than the inaccuracy of the standard frequency–domain coupling ray theory, and smaller than the additional inaccuracy introduced by many other approximations of the coupling ray theory.
Determination of the reference symmetry axis of a generally anisotropic medium which is approximately transversely isotropic
Authors: Klimeš Luděk 
Published: July 2016

Abstract
For a given stiffness tensor (tensor of elastic moduli) of a generally anisotropic medium, we estimate to what extent the medium is transversely isotropic (uniaxial) and determine the direction of its reference symmetry axis expressed in terms of the unit reference symmetry vector. If the medium is exactly transversely isotropic (exactly uniaxial), we obtain the direction of its symmetry axis. We can also calculate the first–order and second–order spatial derivatives of the reference symmetry vector which may be useful in tracing the reference rays for the coupling ray theory. The proposed method is tested using various transversely isotropic (uniaxial) and approximately transversely isotropic (approximately uniaxial) media.
Hip Resurfacing: International Perspectives
Authors: Girard Julien 
Published: July 2016

Background The hip resurfacing concept was developed for young and active patients, especially for femoral bone stock preservation. However, concerns about metal-on-metal bearings with adverse reactions to metal debris have led to a drop off in hip-resurfacing procedures. Questions/Purposes The goal of this review is to evaluate our current knowledge of survivorship of second-generation hip resurfacing devices and elaborate international perspectives for product improvement. Methods A comprehensive literature search provided information on national joint arthroplasty registers worldwide with a minimum of 3000 reported hip resurfacings. It culminated in the analysis of six registers. Results Long-term data showed that available hip resurfacing device survivorship ranged from 95 to 99.7% with 10 years of follow-up, in selected patient populations. The criteria for success were well known, male gender, good bone quality, head component size greater than 48 mm, and cup inclination less than 45°. On the other hand, the recent recall of some hip-resurfacing devices has resulted in huge medico-legal problems and has discredited all implants. It has brought about the recent evolution of hip resurfacing. Femoral fixation is now available for cemented and cementless surfaces. Bearings are still always metal-on-metal, but new types have come on board. Newer designs suggest that ceramic-on-ceramic, cross-linked polyethylene, and oxinium may be applied in this configuration. Conclusions In 2015, the evolution of hip resurfacing is ongoing in terms of implant design, alternative bearings, and implant fixation with hopes of improving survivorship.
The Survival of Total Knee Arthroplasty: Current Data from Registries on Tribology
Authors: Civinini Roberto , Carulli Christian , Matassi Fabrizio , Lepri Andrea Cozzi , Sirleo Luigi , Innocenti Massimo 
Published: July 2016

Background Polyethylene (PE) wear is a major contributor to implant loosening following total knee arthroplasty (TKA), and advanced bearings in TKA are being investigated with hopes of reducing or eliminate wear-related loosening. Currently, information on knee tribology is available from national joint registries and may be the best tools to evaluate the efficacy and safety of design innovations in joint arthroplasty. Questions/Purposes We performed a review of national joint registries trying to answer the following questions: “Which is the main factor directly related to revisions rate in TKA?” and “Are there new bearing options better than conventional ones?” Methods A review was performed of all published annual reports of National Joint Registers, as well as of the literature. The search was carried out using and comparing the National Joint Registers. Results Current data from registries for total knee arthroplasty indicates that age is the major factor affecting the outcome of primary total knee replacement. The 10-year cumulative revision rate for non-cross-linked PE was 5.8% and for XLPE it was 3.5%. The effect of cross-linked polyethylene was more evident in the younger patients. The survival of the oxidized zirconium (OxZr) femoral component appears better when compared to a similar age group of patients with conventional group of prostheses. Our review suggests that the revision rates are half for the OxZr components compared to conventional CoCr femoral components. Conclusions Age is the most relevant single factor related to revision rate. Cross-linked PE has a statistical lower revision rate at 10 years compared to conventional PE and, in the OxZr group, the revision rate is 2 times lower than Co-Cr in the same group of age.
Experience with the Distally Based Sural Neurocutaneous Flap for Ankle and Heel Wounds
Authors: Sin-To Kwok , Wing-Leung Chan , Yan-Kit Lau 
Published: July 2016

Background/Purpose Soft tissue loss over the ankle and heel is a challenging issue for reconstructive surgeons. The aim of this study is to present the technique of using sural neurocutaneous flap and analyse the results. Methods From 2002 to 2014, 15 cases of sural flap were performed in the Department of Orthopaedics and Traumatology of United Christian Hospital, Hong Kong. All cases were handled by two hand surgeons. The outcomes and complications were reviewed retrospectively. Results The aetiology included trauma (6 cases), neoplasm (4 cases), Achilles tendon repair wound complication (3 cases) and ulcer (2 cases). The age of patients ranged from 21 years to 82 years (average, 61.9 years). The size ranged from 12 cm2 to 99 cm2. The mean follow-up period was 20 months. Eleven flaps healed successfully without significant complications. Conclusion Sural neurocutaneous flap is a reliable flap design with constant vascular anatomy. There is minimal donor site morbidity, and no major vessels are sacrificed. It provides a durable, pain-free, functionally and aesthetically satisfying coverage for ankle and heel wounds.
Remedying Displacement in Frozen Conflicts: Lessons From the Case of Cyprus
Authors: HADJIGEORGIOU Nasia 
Published: July 2016

AbstractThis article examines the jurisprudence of the European Court of Human Rights, in order to assess the effectiveness of the remedies provided and procedures followed by the Immovable Property Commission (IPC), a mechanism that was established by Turkey in order to remedy displaced Greek Cypriots. It recommends changes for the improvement of the IPC and argues that with their adoption, the Commission could act as a blueprint for the establishment of similar remedying bodies in other frozen conflicts as well. Such institutions are not only important in terms of states’ compliance with their human rights obligations, but can also contribute to the resolution of the underlying conflict itself.
Surveillance for Healthcare-Associated Influenza-Like Illness in Pediatric Clinics: Validity of Diagnosis Codes for Case Identification
Authors: Feemster Kristen A. , Odeniyi Folasade M. , Localio Russell , Grundmeier Robert W. , Coffin Susan E. , Metlay Joshua P. 
Published: July 2016

Compared to chart review, a definition based on the International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis code for healthcare-associated influenza-like illness (HA-ILI) among young children in a large pediatric network demonstrated high positive and negative predictive values. This finding suggests that electronic health record–based definitions for surveillance can accurately identify medically attended outpatient HA-ILI cases for research and surveillance.Infect Control Hosp Epidemiol 2016;1–4
Numerical Simulation of Particle-Gas Flow Through a Fixed Pipe, Using One-Way and Two-Way Coupling Methods
Authors: Namazian Z. , Najafi A. F. , Mousavian S. M. 
Published: July 2016

AbstractA numerical simulation of the particle-gas flow in a vertical turbulent pipe flow was conducted. The main objective of the present article is to investigate the effects of dispersed phase (particles) on continuous phase (gas). In so doing, two general forms of Eulerian-Lagrangian approaches namely, one-way (when the fluid flow is not affected by the presence of the particles) and two-way (when the particles exert a feedback force on the fluid) couplings were used to describe the equations of motion of the two-phase flow. Gas-phase velocities which are within the order of magnitude as that of particles, volume fraction, and particle Stokes number were calculated and the results were subsequently compared with the available experimental data. The simulated results show that when the particles are added, the fluid velocity is attenuated. With an increase in particle volume fraction, particle mass loading and Stokes number, velocity attenuation also increases. Moreover, the results indicate that an increase in particle Stokes number reduces the special limited particle volume fraction, according to which one-way coupling method yields plausible results. The results have also indicated that the significance of particle fluid interaction is not merely a function of volume fraction and particle Stokes number.
STAGING FRIENDSHIP: MUSSOLINI AND HITLER IN GERMANY IN 1937
Authors: GOESCHEL CHRISTIAN 
Published: July 2016

ABSTRACTIn September 1937, Benito Mussolini and Adolf Hitler met in Germany. Millions of ostensibly enthusiastic Germans welcomed the Duce. Here were the world's first two fascist dictators, purportedly united in solidarity, representing the ‘115 million’ Germans and Italians against the Western powers and Bolshevism. Most historians have dismissed the 1937 dictators’ encounter as insignificant because no concrete political decisions were made. In contrast, I explore this meeting in terms of the confluence of culture and politics and argue that the meeting was highly significant. Its choreography combined rituals of traditional state visits with a new emphasis on the personality of both leaders and their alleged ‘friendship’, emblematic of the ‘friendship’ between the Italian and German peoples. Seen through this lens, the meeting pioneered a new style of face-to-face diplomacy, which challenged the culture of liberal internationalism and represented the aim of Fascist Italy and Nazi Germany to create a New Order in Europe. At the same time, analysis of this meeting reveals some deep-seated tensions between both regimes, an observation that has significant implications for the study of fascist international collaboration.
PHRENOLOGY, CORRESPONDENCE, AND THE GLOBAL POLITICS OF REFORM, 1815–1848
Authors: POSKETT JAMES 
Published: July 2016

ABSTRACTLike many nineteenth-century sciences, phrenology had global aspirations. Skulls were collected in Egypt and Ceylon, societies exchanged journals between India and the United States, and phrenological bestsellers were sold in Shanghai and Tokyo. Despite this wealth of interaction, existing accounts treat phrenology within neat national and urban settings. In contrast, this article examines phrenology as a global political project. During an age in which character dominated public discourse, phrenology emerged as a powerful political language. In this article, I examine the role that correspondence played in establishing material connections between phrenologists and their political concerns, ranging from the abolition of slavery to the reform of prison discipline. Two overarching arguments run throughout my case-studies. First, phrenologists used correspondence to establish reform as a global project. Second, phrenology allowed reformers to present their arguments in terms of a new understanding of human character. More broadly, this article connects political thought with the global history of science.
Plant carbon and water fluxes in tropical montane cloud forests
Authors: Gotsch Sybil G. , Asbjornsen Heidi , Goldsmith Gregory R. 
Published: July 2016

Abstract:Tropical montane cloud forests (TMCFs) are dynamic ecosystems defined by frequent, but intermittent, contact with fog. The resultant microclimate can vary considerably over short spatial and temporal scales, affecting the ecophysiology of TMCF plants. We synthesized research to date on TMCF carbon and water fluxes at the scale of the leaf, plant and ecosystem and then contextualized this synthesis with tropical lowland forest ecosystems. Mean light-saturated photosynthesis was lower than that of lowland forests, probably due to the effects of persistent reduced radiation leading to shade acclimation. Scaled to the ecosystem, measures of annual net primary productivity were also lower. Mean rates of transpiration, from the scale of the leaf to the ecosystem, were also lower than in lowland sites, likely due to lower atmospheric water demand, although there was considerable overlap in range. Lastly, although carbon use efficiency appears relatively invariant, limited evidence indicates that water use efficiency generally increases with altitude, perhaps due to increased cloudiness exerting a stronger effect on vapour pressure deficit than photosynthesis. The results reveal clear differences in carbon and water balance between TMCFs and their lowland counterparts and suggest many outstanding questions for understanding TMCF ecophysiology now and in the future.