bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of polymeric nanoparticles with different functionalities to produce new biocatalysts
Authors: Everton Stefanni S. , Pinto Martina C. C. , Neves Thalita , Cipolatti Eliane Pereira , Manoel Evelin Andrade , Freire Denise Maria Guimarães , Schmal Martin , Pinto José Carlos 
Published: October 2024

AbstractThis study aimed to synthesize functionalized nanosupports via emulsion polymerization to develop new promising nanobiocatalyts via enzyme immobilizations. The co‐monomers methyl methacrylate, divinylbenzene and the epoxy monomer glycidyl methacrylate (GMA) were used. The performance of the nanobiocatlysts was evaluated in hydrolysis and esterification reactions after the immobilization of lipase B from Candida antarctica (CAL B). Firstly, the nanosupports functionalized in situ with 25% and 50% w/w of GMA were successfully synthesized. In esterification reactions, the nanobiocatalysts containing 25% (w/w) of GMA were more active, achieving 254 U.g−1, or an enzyme activity per area of 2.8 U.m−2; such value was higher than the one obtained when the commercial matrix Octadecyl Sepabeads was used (328 U.g−1, 2.4 U.m−2). Such results point out that there is an optimum concentration of GMA epoxide groups that should be incorporated into the supports. The greater enzymatic activity obtained for 25% of GMA nanobiocatalyst was achieved not only because of their textural properties, but also due to a favorable interaction between the epoxide groups and CAL B. These results highlight the potential use of the heterofunctional matrices for the synthesis of new market‐competitive biocatalysts.
Stable Long‐Term Cycling of Room‐Temperature Sodium‐Sulfur Batteries Based on Non‐Complex Sulfurised Polyacrylonitrile Cathodes
Authors: Blázquez‐Moreno Jesús M. , Páez Jerez Ana L. , Tesio Alvaro Y. , Benítez Almudena , Caballero Álvaro 
Published: October 2024

AbstractThe cost‐effectiveness and high theoretical energy density make room‐temperature sodium‐sulfur batteries (RT Na−S batteries) an attractive technology for large‐scale applications. However, these batteries suffer from slow kinetics and polysulfide dissolution, resulting in poor electrochemical performance. The sulfurised polyacrylonitrile (SPAN) cathode is postulated as a suitable material due to the retention of sulfur through covalent bonds and the increase in the conductivity of sulfur. Furthermore, in this work the synthesis of SPAN has been carried out using simple synthesis methods, making it scalable, economical, and without the use of toxic compounds. The incorporation of the SPAN material helps mitigate the shuttle effect, reducing the capacity loss and improving both the efficiency and lifespan of Na−S batteries. The SPAN‐based cathode demonstrates that this RT Na−S battery configuration shows high stability, reaching 1000 cycles with a capacity loss per cycle of 0.11 % and a satisfactory specific capacity of 400 mAh/gs at a high rate of 2 C. This study demonstrates that the utilisation of SPAN derived from a non‐complex synthesis can be a viable alternative for enhancing the future of Na−S batteries technology.
Loss of Control Eating in Adults With Impulsive and/or Inattentive Tendencies
Authors: Christie Laura , Smith‐Spark James H. , Teodorini Rachel D. 
Published: October 2024

ABSTRACTObjectivePrevious research has tended to consider impulsive, inattentive, and loss of control eating (LOC) tendencies as symptoms of greater pathologies in treatment‐seeking samples. However, inattentive and impulsive tendencies and LOC often co‐occur. Although LOC is an important diagnostic component of disordered eating (ED), it has recently been argued to be a dysregulated eating behavior in its own right. The purpose of the current self‐report study was, therefore, to investigate the association between impulsive and inattentive tendencies and LOC in adults after accounting for ED.MethodA community sample of 516 adults was surveyed online about their inattentive and impulsive tendencies, LOC, and ED behaviors.ResultsA hierarchical multiple linear regression revealed ED, inattentive, and impulsive symptoms to be independent, significant, positive predictors of LOC.DiscussionThese findings suggest that the levels of inattentive and, to a lesser extent, impulsive tendencies are significantly associated with LOC in adults, even after ED is accounted for. Moreover, inattentive tendencies were found to be more significantly associated with LOC than impulsive tendencies. These are novel and important findings that can be used to inform both clinicians and individuals with inattentive and impulsive tendencies alike of this association. Considering the well‐documented adverse health and wellbeing outcomes associated with LOC, future feasibility trials are needed aimed at treating this co‐occurrence.
Circular economy practices in international business: What do we know and where are we heading?
Authors: Kansheba Jonathan Mukiza , Fubah Clavis Nwehfor , Acikdilli Gaye 
Published: October 2024

AbstractThe circular economy (CE) has gained the focus of scholars and policymakers as it is related to achieving sustainable development. Multinational corporations (MNCs) are adopting and implementing CE models, especially given their resources, global presence, and ability to share best practices across borders. However, a knowledge gap exists on how CE is practiced within the international business (IB) context. This study seeks to harmonize the existing literature on CE practices in IB using a bibliometric and systematic literature (content) review approach. Our findings of citation and network analyses using the co‐authorship, citation, co‐citation, bibliometric coupling, and co‐occurrence techniques provide the current situation as well as identify three trending research themes in the CE‐IB literature. The study also offers several potential avenues for future research.
Future sick leave, disability pension, and unemployment among patients with cancer after returning to work: Swedish register‐based matched prospective cohort study
Authors: Hiyoshi Ayako , Alexanderson Kristina , Tinghög Petter , Cao Yang , Fall Katja , Montgomery Scott 
Published: October 2024

AbstractIntroductionDespite increasing numbers of working‐age cancer survivors, evidence on their future work‐related circumstances is limited. This study examined their future sick leave, disability pension, and unemployment benefits compared to matched cancer‐free individuals.MethodsA matched cohort study was conducted using nationwide Swedish registers. In total, 94,411 individuals aged 25 to 59 years when diagnosed with incident cancer in 2001–2012 and who returned to work after cancer were compared with their matched cancer‐free individuals (N = 354,814). Follow‐up started from the year before cancer diagnosis and continued up to 14 years. Generalized estimating equations were used to calculate incidence rate ratios (IRR) and odds ratios for the difference between cancer survivors and matched cancer‐free individuals.ResultsCompared with cancer‐free individuals, cancer survivors had six times higher sick‐leave days per year after cancer (IRR 6.25 [95% CI, 5.97–6.54] for men; IRR, 5.51 [5.39–5.64] for women). This higher number of sick‐leave days declined over time but a two‐fold difference persisted. An approximate 1.5 times higher risk of receiving disability pension remained during follow‐up. The unemployment days tended to be lower for cancer survivors (IRR, 0.84 [0.75–0.94] for men; IRR, 0.91 [0.86–0.96] for women). Risk of sick leave and disability pension was higher among those with leukemia, colorectal, and breast cancer than skin and genitourinary cancers.ConclusionsCancer survivors who returned to work experienced a high and persisting sick leave and disability pension for over a decade. Prolonged receipt of a high amount of benefits may have long‐term adverse impacts on financial circumstances; more knowledge to promote the environment that encourages returning to and remaining in work is needed.
Single‐cell multiplex immunocytochemistry in cell block preparations of metastatic breast cancer confirms sensitivity of GATA‐binding protein 3 over gross cystic disease fluid protein 15 and mammaglobin
Authors: Li Joshua J. X. , Cheng Hiu Yu , Lee Conrad H. C. , Ng Joanna K. M. , Tsang Julia Y. , Tse Gary M. 
Published: October 2024

AbstractBackgroundMetastatic breast cancers are frequently encountered in cytology and require immunocytochemistry (ICC). In this study, traditional and multiplex ICC (mICC) for GATA‐binding protein 3 (GATA3), gross cystic disease fluid protein 15 (GCDFP15), and mammaglobin (MMG) were performed with the aim of validating mICC in cell blocks, with further single‐cell expression pattern analysis to identify the single markers and combinations of markers most sensitive in subtypes of breast cancer.MethodsGATA3, GCDFP15, and MMG were paired with OptiView 3,3′‐diaminobenzidine and Ventana DISCOVERY Purple and Blue, respectively, with cyclical and serial staining. Bright‐field imaging was performed with the Mantra 2 system and analyzed with the inForm Tissue Finder (Akoya Biosciences). Cell detection and phenotyping were further confirmed by two pathologists.ResultsIn the 36 cases studied, traditional ICC and mICC demonstrated good concordance (kappa coefficient, >0.5; p < .01) at three cutoffs (1%, 5%, and 50%), except for GATA3 at the 1% cutoff. Single‐marker positivity outnumbered double‐marker positivity and the exceedingly rare triple‐marker positivity (<3%). GATA3 was the leading single marker–positive phenotype in all breast cancer subtypes, except for MMG in estrogen receptor–positive, progesterone receptor–positive, and human epidermal growth factor receptor 2–positive (ER+/PR+/HER2+) breast cancers. Limited to two markers, GATA3/MMG included the greatest number of tumor cells for luminal breast cancers (ER+/PR+/HER2+, 60.6%; ER+/PR+/HER2+, 31.4%), whereas HER2‐overexpressed breast cancers (27.4%) and triple‐negative breast cancers (26.4%) favored the combination of GATA3/GCDFP15.ConclusionsFor a single marker, GATA3 displayed the highest sensitivity. The addition of MMG for hormone receptor‐positive breast cancers and GCDFP15 for hormone receptor‐negative breast cancers further increased sensitivity. The low proportion of multimarker‐positive cells suggested that the coexpression observed with traditional ICC is attributable to intratumoral heterogeneity, not genuine coexpression.
A cluster‐based incremental potential approach for reduced order homogenization of bones
Authors: Ju Xiaozhe , Xu Chunli , Xu Yangjian , Liang Lihua , Liang Junbo , Tao Weiming 
Published: October 2024

AbstractWe develop a cluster‐based model order reduction (called C‐pRBMOR) approach for efficient homogenization of bones, compatible with a large variety of generalized standard material (GSM) models. To this end, the pRBMOR approach based on a mixed incremental potential formulation is extended to a clustered version for a significantly improved computational efficiency. The microscopic modeling of bones falls into a mixed incremental class of the GSM framework, originating from two potentials. An offline phase of the C‐pRBMOR approach includes both a clustering analysis spatially decomposing the micro‐domain within an RVE and a space–time decomposition of the microscopic plastic strain fields. A comparative study on two different clustering approaches and two algorithms for mode identification is additionally conducted. For an online analysis, a cluster‐enhanced version of evolution equations for the reduced variables is derived from an effective incremental variational formulation, rendering a very small set of nonlinear equations to be numerically solved. Several numerical examples show the effectiveness of the C‐pRBMOR approach. A striking acceleration rate beyond 104 against conventional FE computations and that beyond 103 against the original pRBMOR approach are observed.
Rational Strategies for Preparing Highly Efficient Tin‐, Bismuth‐ or Indium‐Based Electrocatalysts for Electrochemical CO2 Reduction to Formic acid/Formate
Authors: Yang Ziyuan , Jin Yuxia , Feng Zhongbao , Luo Peng , Feng Changrui , Zhou Yifan , An Xiaowei , Hao Xiaogang , Abudula Abuliti , Guan Guoqing 
Published: October 2024

AbstractElectrochemical carbon dioxide reduction reaction (CO2RR) is an environmentally friendly and economically viable approach to convert greenhouse gas CO2 into valuable chemical fuels and feedstocks. Among various products of CO2RR, formic acid/formate (HCOOH/HCOO−) is considered the most attractive one with its high energy density and ease of storage, thereby enabling widespread commercial applications in chemical, medicine, and energy‐related industries. Nowadays, the development of efficient and financially feasible electrocatalysts with excellent selectivity and activity towards HCOOH/HCOO− is paramount for the industrial application of CO2RR technology, in which Tin (Sn), Bismuth (Bi), and Indium (In)‐based electrocatalysts have drawn significant attention due to their high efficiency and various regulation strategies have been explored to design diverse advanced electrocatalysts. Herein, we comprehensively review the rational strategies to enhance electrocatalytic performances of these electrocatalysts for CO2RR to HCOOH/HCOO−. Specifically, the internal mechanism between the physicochemical properties of engineering materials and electrocatalytic performance is analyzed and discussed in details. Besides, the current challenges and future opportunities are proposed to provide inspiration for the development of more efficient electrocatalysts in this field.
Recent Progress in the Electrochemical Formation of C−N Bonds for Construction of Organic Compounds via the Use of NOx/NOx−
Authors: Wu Shutao , Liu Fei 
Published: October 2024

AbstractEmissions of nitrogen oxide (NOx) species (NO and NO2) and nitrate/nitrite NOx−, such as NO3− and NO2−, have led to serious water pollution and climate challenges. How to remove these wastes is a global problem that urgently needs to be addressed. As reported, electrochemical catalytic technology under ambient conditions is of great interest for NOx/NOx− removal. Additionally, the in situ utilization of surface‐adsorbed nucleophilic intermediates generated from the electrochemical reduction of NOx/NOx− can provide a sustainable strategy for building C−N bonds, upgrading waste NOx/NOx− into value‐added organic products, such as amines, oximes, amides, and amino acids, while remediating the environment. This review summarizes the most recent progress in the construction of nitrogen compounds by coupling electrochemical NOx/NOx− reduction reactions with inorganic/organic substrates, focuses on understanding the adsorption–transformation mechanism during the NOx/NOx− reduction process, and discusses multiple side reactions and complex pathways. Important strategies, such as coupled system development and catalyst preparation, are also presented to broaden the range of nitrogen compounds and improve yields. Finally, a few key challenges and future research directions for the development of efficient and low‐cost electrochemical C−N coupling processes are discussed.
Meconium as an Analyte for Androgen Exposure: Analysis Through Varying Maternal‐Fetal Biomarkers
Authors: Knudsen Nicole , Tang Stacey , Lauzon Sylvie , Dhaurali Supriya , Snyder Nathaniel W. , Voegtline Kristin M. 
Published: October 2024

ABSTRACTMeconium, the first stool produced by neonates, has been used as an analyte for exogenous fetal exposures. However, few studies have investigated the relationship between meconium and androgen exposure in utero. Here, we examine the associations of testosterone and dehydroepiandrosterone (DHEA) across maternal antenatal salivary testosterone, cord blood, meconium, and infant salivary testosterone. A total of 47 women with singleton, uncomplicated pregnancies, and their infants were included in this study. Participants were recruited from an academic obstetric clinic. Maternal saliva was collected at 36‐weeks’ gestation. Cord blood and meconium were collected at birth. Infant salivary testosterone was collected at 1 and 4 weeks of age. Multivariate model results showed that meconium testosterone was associated with neonatal testosterone at 1 (F = 5.62, p = 0.029) and 4 weeks (F = 4.28, p = 0.048) postnatal age; no sex differences were detected. This study suggests meconium is a valuable tool for evaluating endogenous androgen exposure and should be used in future studies to investigate the fetal hormonal milieu.
A Supramolecular Gel that Exhibits Multi‐Stimuli Responsiveness and High Conductivity through Host‐Guest Interactions
Authors: Wang Jie , Wu Xiaojing , Cai Hongyan , Li Hang , Zhang Pizheng , Qin Bo 
Published: October 2024

AbstractA network‐structured supramolecular gel is constructed through host‐guest interactions between conjugated ligands and metal ions, leading to enhanced mechanical properties and excellent electrical conductivity. This overcomes the problem of insufficient conductance due to the presence of solvent in the interstitial region of the supramolecular gel. Supramolecular gels can undergo reversible sol‐gel transitions by controlling the pH or temperature of the system. In addition, a method has been developed to determine the specific binding ratio of host‐guest molecules by conductivity tests, and has been used to verify the specific binding ratio of crown ether to potassium ions. To explain the high conductivity of supramolecular metallic gels, DFT and SEM have been employed to elucidate their conductivity mechanism.
Model‐ versus data‐uncertainty for concrete members and connections in cyclic loading
Authors: Fardis Michael N. 
Published: October 2024

AbstractLarge databases of cyclic tests on flexure‐ or shear‐critical concrete members and shear‐critical connections of columns to beams or slabs are used to estimate the uncertainty inherent in experimental data in literature—as read by users. To this end, the predictions of two different, presumably independent, design‐oriented models for the properties of interest are used to establish the “central tendency” of data, against which individual tests or small groups thereof are assessed. Properties considered are: (a) the cyclic ultimate chord‐rotation of flexure‐controlled members with continuous or lap‐spliced deformed bars, (b) the cyclic shear strength of shear‐critical members, (c) the chord‐rotation at yielding of rectangular columns with plain bars, and (d) the cyclic shear strength of shear‐controlled beam‐column and slab‐column joints. Results suggest that the data from each test campaign have a certain degree of bias, specific to it. Test campaigns with ratio of estimated average deviation from the “central tendency” to the standard deviation of campaign deviations (called “data uncertainty”) which is far into the tail of the Normal distribution may be excluded as questionable. This systematic bias, along with other types of “data uncertainty” addressed in this work, seem to contribute to the apparent scatter of model predictions with respect to cyclic test results the equivalent of a coefficient of variation of model‐to‐test‐ratio of at least 10% and possibly as high as 25%–30%. Model uncertainty seems to contribute to this scatter the equivalent of a coefficient of variation of at least 15% in shear‐controlled connections, or as much as 25% in the case of flexural deformation capacity of members with deformed bars; the cyclic shear resistance of members and—with the reservation of the small number of tests—the chord‐rotation at yielding of members with plain bars, are in‐between.
Acrylamide induces spatiotemporal metabolic profiling disturbance via targeting taurine and hypotaurine metabolism during early zebrafish development
Authors: Wang Anli , Zeng Jia , Song Xiaoran , Huang Yingyu , Yao Jianxin , Zhu Li , Gao Yuchen , Wang Binjie , Wu Yuanzhao , Xu Zhongshi , Zheng Ruonan , Qin Yazhou , Wang Jiye , Yao Weixuan , Wan Xuzhi , Li Haoyu , Zhuang Pan , Jiao Jingjing , Zhuang Shulin , Zhang Yu 
Published: October 2024

AbstractAcrylamide, an endocrine‐disrupting emerging contaminant from both the environment and food processing, has been linked to cardiac developmental toxicity in zebrafish. However, the mechanisms involved in the cardiac developmental toxicity from long‐term exposure to acrylamide remain unclear. This study provides in‐depth evidence on the metabolic regulation of zebrafish embryos with acrylamide exposure. A comprehensive metabolites analysis of four different acrylamide exposures (0, 0.5, 1.0, and 2.0 mM) at different zebrafish developmental stages (6, 24, 48, 72, 96, and 120 h post fertilization, hpf) was performed. Metabolite changes throughout the zebrafish development (6–120 hpf) were closely associated with taurine and hypotaurine metabolism. The pattern of significantly changed metabolites revealed that acrylamide strongly disrupts taurine and hypotaurine metabolism related to a deficient cardiovascular system. Moreover, acrylamide exposure disrupted the de novo synthesis of taurine via cysteine sulfinic acid decarboxylase during early zebrafish embryogenesis. In addition, taurine supplementation (10 mM) effectively alleviates acrylamide‐induced deficient cardiovascular system. Our results demonstrate that acrylamide exposure has a detrimental effect on early heart development in zebrafish due to the inhibition of de novo synthesis of taurine.
A finite volume scheme employing the multipoint flux approximation with diamond stencil for the diffusive‐viscous wave equation on general polyhedral meshes
Authors: Yang Di , Gao Zhiming , Yan Wenjing 
Published: October 2024

AbstractBased on three‐dimensional seismic wave, simulations have become a pivotal aspect of seismic exploration. The diffusive‐viscous wave equation, initially proposed by Goloshubin et al., is frequently utilized to describe seismic wave propagation in fluid‐saturated media. However, obtaining numerical solutions for this equation has become an urgent issue in recent years. In this study, we present a cell‐centered finite volume scheme utilizing a multipoint flux approximation that employs a “diamond stencil” on general polyhedral meshes to address the diffusive‐viscous wave equation. Numerical tests exhibit that this new scheme attains optimal convergence, and its effectiveness is demonstrated through simulating vibrations induced by an earthquake source.
Effects of Waste Generation on the Load Capacity Factor: A Novel Waste Management Assessment for OECD Countries
Authors: Pata Ugur Korkut , Pata Selin Karlilar , Erdogan Sinan 
Published: October 2024

ABSTRACTThe increase in global waste generation is an important issue directly addressed in the Sustainable Development Goal (SDG)‐12 and OECD countries produce large amounts of waste. In this context, the study examines the influence of waste generated and recycled on the load capacity factor (biocapacity/ecological footprint) in 28 OECD countries from 2000 to 2021 using novel panel data approaches. The study employs augmented mean group and novel half‐panel jackknife estimation approaches within the Load Capacity Curve (LCC) hypothesis and confirms the LCC for OECD nations. In addition, the long‐term prediction results illustrate that waste generation increases environmental destruction, while waste recycled supports the increase in the load capacity factor. The study recommends policymakers in OECD countries to support economic growth and increase investment in waste recycling technologies to achieve SDG‐12.