bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subjective Spatial Navigation Complaints - A Frequent Symptom Reported by Patients with Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer's Disease
Authors: Cerman Jiri , Andel Ross , Laczo Jan , Vyhnalek Martin , Nedelska Zuzana , Mokrisova Ivana , Sheardova Katerina , Hort Jakub 
Published: November 2017

Background:
Great effort has been put into developing simple and feasible tools capable to
detect Alzheimer's disease (AD) in its early clinical stage. Spatial navigation impairment occurs very
early in AD and is detectable even in the stage of mild cognitive impairment (MCI).

Objective:
The aim was to describe the frequency of self-reported spatial navigation complaints in patients
with subjective cognitive decline (SCD), amnestic and non-amnestic MCI (aMCI, naMCI) and AD
dementia and to assess whether a simple questionnaire based on these complaints may be used to detect
early AD.

Method:
In total 184 subjects: patients with aMCI (n=61), naMCI (n=27), SCD (n=63), dementia due to
AD (n=20) and normal controls (n=13) were recruited. The subjects underwent neuropsychological examination
and were administered a questionnaire addressing spatial navigation complaints. Responses to
the 15 items questionnaire were scaled into four categories (no, minor, moderate and major complaints).

Results:
55% of patients with aMCI, 64% with naMCI, 68% with SCD and 72% with AD complained
about their spatial navigation. 38-61% of these complaints were moderate or major. Only 33% normal
controls expressed complaints and none was ranked as moderate or major. The SCD, aMCI and AD dementia
patients were more likely to express complaints than normal controls (p's<0.050) after adjusting
for age, education, sex, depressive symptoms (OR for SCD=4.00, aMCI=3.90, AD dementia=7.02) or
anxiety (OR for SCD=3.59, aMCI=3.64, AD dementia=6.41).

Conclusion:
Spatial navigation complaints are a frequent symptom not only in AD, but also in SCD and
aMCI and can potentially be detected by a simple and inexpensive questionnaire.
Identification of Bone Metastasis-associated Genes of Gastric Cancer by Genome-wide Transcriptional Profiling
Authors: Lin Mingzhe , Li Xin , Guo Haizhou , Ji Faxiang , Ye Linhan , Ma Xuemei , Cheng Wen 
Published: November 2017

Background:Gastric cancer is one of the leading causes of cancer-related mortality worldwide. Genome-wide transcriptional profiling has provided valuable insights into the molecular basis underlying processes involved in gastric cancer initiation and progression. </P><P> Objective: To understand the pathological and biological mechanisms of gastric cancer metastasis in a genome-wide context. </P><P> Method: In this study, we constructed libraries from blood of gastric cancer patients with, and without, bone metastasis. High-throughput sequencing combined with differential expression analysis was used to investigate transcriptional changes.Results:We identified a total of 425 significantly differentially expressed genes. Protein-protein interaction network analysis suggested that most of these genes are involved in DNA replication, DNA damage response, collagen homeostasis and cell adhesion. Furthermore, our data suggested that NFkappaB and DNA damage response pathways were the key regulators of the bone metastasis associated with gastric cancer. Finally, most of these target genes were involved in pathways such as extracellular matrix organization and extracellular structure organization as revealed by gene set enrichment assay.Conclusion:Our study provides a comprehensive analysis of the transcriptional alterations involved in gastric cancer bone metastasis, which provides greater insights into the complexity of regulatory changes during tumorigenesis and offers novel diagnostic as well as therapeutic avenues.
Predicting Outcome in Patients with Anti-GBM Glomerulonephritis
Authors: van Daalen Emma E. , Jennette J. Charles , McAdoo Stephen P. , Pusey Charles D. , Alba Marco A. , Poulton Caroline J. , Wolterbeek Ron , Nguyen Tri Q. , Goldschmeding Roel , Alchi Bassam , Griffiths Meryl , de Zoysa Janak R. , Vincent Beula , Bruijn Jan A. , Bajema Ingeborg M. 
Published: November 2017

Background and objectives
Large studies on long-term kidney outcome in patients with anti-glomerular basement membrane (anti-GBM) GN are lacking. This study aimed to identify clinical and histopathologic parameters that predict kidney outcome in these patients.

Design, setting, participants, & measurements
This retrospective analysis included a total of 123 patients with anti-GBM GN between 1986 and 2015 from six centers worldwide. Their kidney biopsy samples were classified according to the histopathologic classification for ANCA-associated GN. Clinical data such as details of treatment were retrieved from clinical records. The primary outcome parameter was the occurrence of ESRD. Kidney survival was analyzed using the log-rank test and Cox regression analyses.

Results
The 5-year kidney survival rate was 34%, with an improved rate observed among patients diagnosed after 2007 (P=0.01). In patients with anti-GBM GN, histopathologic class and kidney survival were associated (P<0.001). Only one of 15 patients with a focal class biopsy sample (≥50% normal glomeruli) developed ESRD. Patients with a sclerotic class biopsy sample (≥50% globally sclerotic glomeruli) and patients with 100% cellular crescents did not recover from dialysis dependency at presentation. In multivariable analysis, dialysis dependency at presentation (hazard ratio [HR], 3.17; 95% confidence interval [95% CI], 1.59 to 6.32), percentage of normal glomeruli (HR, 0.97; 95% CI, 0.95 to 0.99), and extent of interstitial infiltrate (HR, 2.02; 95% CI, 1.17 to 3.50) were predictors of ESRD during follow-up.

Conclusions
Dialysis dependency, low percentage of normal glomeruli, and large extent of interstitial infiltrate are associated with poor kidney outcome in anti-GBM GN. Kidney outcome has improved during recent years; the success rate doubled after 2007.

Podcast
This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2017_11_21_CJASNPodcast_18_1_v.mp3
Museus, educação e laboratórios experimentais
Authors: Bejarano Barco Jorge 
Published: November 2017

Durante a última década estive trabalhando em projetos educativos em vários museus de arte e em colaboração com alguns espaços independentes de Medellín, Colômbia. Neste texto para a Revista GEARTE proponho algumas reflexões baseadas em minha experiência no campo da educação em museus e dos laboratórios experimentais. Não pretende ser um artigo em seu sentido stricto, mas uma série de notas modulares, curtas e em desenvolvimento sobre temas que considero pertinentes para pensar o museu e a educação como dimensões contemporâneas e em constante transformação.
PARTISIPASI	POLITIK MASYARAKAT PEDESAAN DALAM PEMILIHAN GUBERNUR JAWA TENGAB TAHUN 2008 (Studi Kasus mengenai Partisipasi Politik Masyarakat Pedesaan di Kecamatan Karanggede, Boyolali dalam Pilgub Jateng 2008)
Authors: Wijaya Sri Herwindya Baskara 
Published: November 2017

<p><em>Every citizen has interest and preference on who should command him/her and</em></p><p><em>on the public policy</em><em>.</em><em> </em><em>The directly election of local leader is part of citizen contribution to the public policy corresponding to the Act No</em><em>.</em><em> </em><em>32 of 2004 about Local Government</em><em>. </em><em>That the governor and vice governor position is not based on the election mechanism by </em><em>DPRD </em><em>like the previous age</em><em>. </em><em>Thus, the society is political participation </em><em>has </em><em>a very important role here. Based on the result of research shows that generally, the rural society in subdistrict Karanggede Boyolali </em><em>has </em><em>the lower participation level in the Central Java's Governor of 2008</em><em>.</em></p>
Memahami Komunikasi Kelompok dalam Pendampingan Korban Kekerasan Jerbasis Gender
Authors: Setiawan Yuliyanto Budi 
Published: November 2017

<p><em>Through this study, some topics</em><em>/</em><em>themes </em><em>which where ever communicated by participants together in a meeting of Support Group, among others violence cases experienced by each member/victim, the form of gender emancipation and </em><em>anti-</em><em>' </em><em>trafficking. The obstacles experienced by a member when her violence case was being handled by the police</em><em>, </em><em>a </em><em>discussion of the adaptation of Support Group with its surrounding environment, felt by the victim</em><em>, </em><em>discussion of business development of the member, the distribution of petrol fund from the Semarang City Government for the unable community as well as discussions on the content of UP-PKDRT No.23/2004. Counselor/Facilitator was noted to use the method of Art Therapy and Method of Discussion during facilitating victims in the mentioned therapy group.</em></p>
Media Sosial yang Dibenci yang Ditakuti
Authors: Watie Errika Dwi Setya 
Published: November 2017

<p><em>Social media users came from every part of society. The presence and acceptance of social media, of course, not only have an impact on the lives of individual users directly, but it is also have an impact on the lives of the state concerned. It should be understood, that the mass media has the ability to build the image and opinions in the minds of users. Currently there are 6 types of social media are present in the community. the negative impact of social media in fact also present along with the increasing positive impact. The number of negative cases that accompany the presence of social media, making social media seems to be something scary. Therefore, should be wise in using social media. </em></p>
Factors Analysis And Profit Achievement For Trading Company By Using Rough Set Method
Authors: Sembiring Muhammad Ardiansyah , Azhar Zulfi 
Published: November 2017

This research has been done to analysis the financial raport fortrading company and it is intimately related to some factors which determine the profit of company. The result of this reseach is showed about New Knowledge and perform of the rule. In discussion, by followed data mining process and using Rough Set method. Rough Set is to analyzed the performance of the result. This reseach will be assist to the manager of company with draw the intactandobjective. Rough set method is also to difined the rule of discovery process and started the formation about Decision System, Equivalence Class, Discernibility Matrix, Discernibility Matrix Modulo D, Reduction and General Rules. Rough set method is efective model about the performing analysis in the company. Keywords : Data Mining, General Rules, Profit,. Rough Set.
Niche shifts after long‐distance dispersal events in bipolar sedges (Carex, Cyperaceae)
Authors: Villaverde Tamara , González‐Moreno Pablo , Rodríguez‐Sánchez Francisco , Escudero Marcial 
Published: November 2017

PREMISE OF THE STUDY:Bipolar species represent the greatest biogeographical disjunction on Earth, raising many questions about the colonization and adaptive processes behind such striking distribution. We investigated climatic niche differences of five Carex bipolar species in North and South America to assess niche shifts between these two regions. Moreover, we assessed potential distribution changes with future climate change.METHODS:We used 1202 presence data points from herbarium specimens and 19 bioclimatic variables to assess climatic niche differences and potential distributions among the five species using ordination methods and Maxent.KEY RESULTS:The niche overlap analyses showed low levels of niche filling and high climatic niche expansion between North and South America. Carex macloviana and C. maritima showed the greatest niche expansion (60% and 96%, respectively), followed by C. magellanica (45%) and C. microglochin (39%). Only C. canescens did not colonize new environments (niche expansion = 0.2%). In contrast, all species but C. magellanica had niche filling that was <40%; hence, they are absent in the south from many environments they inhabit in North America. Climate change will push all species toward higher latitudes and elevation, reducing the availability of suitable environments.CONCLUSIONS:The colonization of South America seems to have involved frequent climatic niche shifts. Most species have colonized new environments from those occupied in the North. Observed niche shifts appear congruent with time since colonization and with current genetic structure within species. In these cold‐dwelling species, climate change will most likely decrease their suitable environments in the future.
Safety of Peritoneal Dialysis after Nonrenal Solid-Organ Transplantation
Authors: Buffet Anne , Guillouët Sonia , Lobbedez Thierry , Ficheux Maxence , Lanot Antoine , Béchade Clémence 
Published: November 2017

Background End-stage renal disease is a well-known complication after solid-organ transplantation, mostly as a result of calcineurin-inhibitor therapy. Among recipients of solid-organ transplants other than kidneys, peritoneal dialysis (PD) has been considered an accessory technique as an increased risk of infectious complications has been reported. The aim of our study was to evaluate the outcome of patients with a liver, heart, or lung transplant who underwent PD for replacement therapy. Methods This was a retrospective, monocentric study. Every adult patient starting PD between January 1, 2001, and December 31, 2016, at our center was included. The history of previous solid-organ transplantation was determined. For the statistical analysis, we considered 2 groups of patients: 1 group having a history of transplantation of an organ other than the kidney (lung, heart, liver), and 1 group that was starting dialysis without any prior history of organ transplantation. Patients who had previously undergone kidney transplantation were excluded. The events of interest were the first peritonitis episode, death, and PD failure, defined as transfer to hemodialysis. Results A total of 383 patients started PD during this period, 13 of whom had a history of organ transplantation. We found no significant difference between the solid-organ transplantation patients and those without a history of transplantation in terms of the occurrence of peritonitis (HR [hazard ratio] 0.91 [0.37 – 2.22]), death (HR 0.83 [0.26 – 2.63]), and PD failure (HR 1.01 [0.32 – 3.22]). Conclusion Peritoneal dialysis appears to be an effective replacement therapy for patients with a previous history of solid-organ transplantation.
Peritoneal Dialysis in Orthotopic Liver Transplantation Recipients
Authors: Saiprasertkit Nalinee , Nihei Camila H. , Bargman Joanne M. 
Published: November 2017

Background In many dialysis programs, there is resistance to initiating peritoneal dialysis (PD) in liver transplant patients needing renal replacement therapy. This retrospective study reviews the outcome of PD in liver transplant patients at a major transplantation and dialysis center. Method We performed a retrospective cohort study in patients who underwent liver transplants and received PD between 1991 and 2016. Patient demographics, laboratory parameters, and adverse events were collected from our electronic database. Results Between 1991 and 2016, 14 patients underwent liver transplants and subsequently received PD. The mean age was 59.0 ± 7.1 years; 42.8% women; the mean time from transplant to PD initiation was 9.7 ± 2.8 years; average follow-up on PD was 31.3 months (range: 9 – 87 months). Hepatitis C was the main cause of liver failure necessitating the transplant (8 patients). Calcineurin inhibitor toxicity was the lead cause of end-stage renal disease (ESRD) (12 patients). The overall peritonitis rate was 39.8 patient-months (0.3 episodes per year at risk). There was 1 patient with relapsing peritonitis, and 1 patient had severe peritonitis and died. Mean survival was 58.9 ± 11.3 months, 4 patients died, 4 received a kidney transplant, 1 patient was transitioned to hemodialysis due to poor ultrafiltration, 1 patient was transferred to another program, 2 remained on PD and 2 patients recovered renal function. Eight patients underwent liver biopsies during their time on PD without complication. Conclusion There appears to be no specific concern related to liver transplant patients undergoing PD. Peritonitis and mortality rates were no different from other solid organ recipients or even from the general PD population. The hepatic graft was never threatened, even during peritonitis. Therefore, these patients should not be denied the option of PD.
Lessons from the Short GRB 170817A: The First Gravitational-wave Detection of a Binary Neutron Star Merger
Authors: Granot Jonathan , Guetta Dafne , Gill Ramandeep 
Published: November 2017

Abstract
The first, long-awaited, detection of a gravitational-wave (GW) signal from the merger of a binary neutron star (NS–NS) system was finally achieved (GW170817) and was also accompanied by an electromagnetic counterpart—the short-duration gamma-ray burst (GRB) 170817A. It occurred in the nearby (

Mpc) elliptical galaxy NGC 4993 and showed optical, IR, and UV emission from half a day up to weeks after the event, as well as late-time X-ray (at

days) and radio (at

days) emission. There was a delay of

between the GW merger chirp signal and the prompt GRB emission onset, and an upper limit of

was set on the viewing angle w.r.t the jet’s symmetry axis from the GW signal. In this letter we examine some of the implications of these groundbreaking observations. The delay

sets an upper limit on the prompt GRB emission radius,

, for a jet with sharp edges at an angle

. GRB 170817A’s relatively low isotropic equivalent γ-ray energy output may suggest a viewing angle slightly outside the jet’s sharp edge,

, but its peak

photon energy and afterglow emission suggest instead that the jet does not have sharp edges and the prompt emission was dominated by less energetic material along our line of sight, at

. Finally, we consider the type of remnant that is produced by the NS–NS merger and find that a relatively long-lived (

s) massive NS is strongly disfavored, while a hyper-massive NS of lifetime

appears to be somewhat favored over the direct formation of a black hole.
Terminologie, terminographie et métalangue guillaumienne : problèmes actuels
Authors: Bottineau Didier 
Published: November 2017

Résumé La métalangue guillaumienne est connue pour sa remarquable complexité. Sa genèse est historiquement orientée par divers paramètres : la dialectique de la continuité et de la rupture avec Saussure ; le rejet de la logique au profit d’un mentalisme dynamique situé dans le sujet parlant ; les relations variables à la psychologie et aux neurosciences ; l’évolution du discours de l’auteur d’un matérialisme réaliste vers une modélisation toujours plus abstraite. Il en résulte un bilan pour le moins contrasté : une métalangue spécifique dont la légitimité se renégocie constamment, doublée d’une influence particulière sur la terminologie la plus classique ; cette hétérogénéité transparaît tant dans la pragmatique des guillaumiens, néo- et trans-guillaumiens actuels, que dans l’existence même de plusieurs dictionnaires terminologiques de la langue de Guillaume, caractérisés par des options terminographiques contrastées.
La « signologie » saussurienne des Notes item (1897-1900) : une terminologie hétérodoxe
Authors: Gandon Francis 
Published: November 2017

Résumé Les Notes Item (1897-1900) font partie de la deuxième étape, selon Amacker (2001) de la pensée de Saussure : celle de la multiplicité des points de vue. Elles oscillent, de fait, du point de vue du locuteur à celui du mot en soi, du signe isolé au système, du synchronique au diachronique. La terminologie des Notes se confronte à une double aporie : remplacer la terminologie existante, jugée inepte ; suturer le gouffre entre points de vue divergents. On s’explique que leur exceptionnelle richesse soit restée sans postérité.
La particule a-t-elle un statut en grammaire anglaise ?
Authors: Guimier Claude 
Published: November 2017

Résumé L’article se donne comme objectif l’examen des emplois du terme « particule » en grammaire anglaise. Le terme a été longtemps utilisé pour désigner l’ensemble des mots indéclinables. Il est également utilisé pour faire référence à des unités qui ne se laissent pas catégoriser dans les classes de mots dont l’existence est postulée par les grammairiens. La liste en est ouverte, mais on y trouve notamment that pronom relatif, to marqueur d’infinitif et les particules adverbiales. Certaines grammaires toutefois proposent de recatégoriser ces unités dans des classes préétablies.
Le connecteur histoire (de) au regard de ses occurrences dans Frantext
Authors: Legallois Dominique 
Published: November 2017

Résumé La première partie de cet article propose une critique du terme de locution prépositive appliqué au connecteur histoire de + inf . Cette expression ne peut en effet être caractérisée par sa seule fonction prépositive, et la notion de locution ne peut lui être appliquée. La seconde partie propose un examen des occurrences du connecteur dans Frantext (datation, constructions, collocations) ; à partir d’observations, nous faisons quelques hypothèses sur les origines de la grammaticalisation d’ histoire de , et nous posons les caractéristiques sémantiques les plus importantes de la construction.
Sémantique du web vs . Semantic Web ?
Authors: Rastier François 
Published: November 2017

Résumé Le programme du Web sémantique entend remplacer le « Web des documents » par le « Web des données » et prolonge ainsi le programme classique de la représentation des connaissances. En revanche, pour une sémantique du Web inspirée par la linguistique de corpus, les connaissances résident dans les textes et les documents qui les véhiculent. Elles ne peuvent donc en être abstraites sans perdre leur valeur contextuelle et leur pertinence. Cela conduit à recontextualiser la notion même de donnée, ainsi qu’à problématiser le rapport entre données et métadonnées.
Campus Intelligent Safety Supervision System Based on RFID
Authors: Chen Ning , Yue Qingqing 
Published: November 2017

In this paper,for the problem of the security of students in primary and secondary schools,we propose a campus intelligent safety supervision system based on RFID technology.Through the use of RFID technology for non-contact automatic recognition features,the system achieves the goal of supervising the school gate, classroom, danger zone entrance and other places in the primary and secondary schools. Then the information of the acquisition is classified,compared,displayed,alarm,etc.The information is automatically acquired and transmitted in real time, which makes the supervision and management of the school more intelligent.Compared with the existing campus management system, the system can be more accurate access to information in real-time, improve the convenience and effectiveness of safety management, and realize the intelligent supervision and management of the students in primary and secondary schools.
Les Maliens en France et aux États-Unis
Authors: Boulanger Claire , Mary Kévin 
Published: November 2017

<p class="resume">Depuis une vingtaine d’années, un nombre croissant d’auteurs s’intéressent à la notion de transnationalisme en tant que paradigme qui permet de sortir de l’analyse unidirectionnelle du fait migratoire (qui oppose notamment pays d’émigration et pays d’immigration) et permet de comprendre l’existence de modes de vies qui transcendent les frontières (Marques, Góis, 2008). Dans cette perspective, les migrants développent des formes actives de participation à des processus économiques, politiques, ou culturels, touchant à la fois la région ou le pays de départ et la région ou le pays de destination, réunis pour l’analyse en un espace social transnational (Faist, 2000). C’est ce que nous entendons ici par « pratiques transnationales ». L’objectif de cet article est d’analyser ces pratiques à travers l’exemple des Maliens en France et aux États-Unis. </p>