bluuebunny/crossref_metadata_2025_split huggingface dataset:
CRYOGENIC RAPIDCREEKITE OF THE MALAYA NIZHNEUDINSKAYA CAVE (EASTERN SIBERIA)
Authors: БАЗАРОВА Е.П. , КАДЕБСКАЯ О.И. , РУБЦОВА М.Н. , КОРОТЧЕНКОВА О.В. , КОНОНОВ А.М. 
Published: September 2024

Методами электронной микроскопии и порошковой дифракции исследованы морфология и минеральный состав криогенных образований пещеры Малая Нижнеудинская, приуроченной к многолетнемерзлым породам. В пещере круглогодично держится околонулевая температура, в результате чего в подземной полости широко развиты ледяные образования. Выявлено, что при замерзании растворов и последующем частичном испарении льда формируется криогенный остаток, сложенный гипсом, кальцитом и редким минералом рапидкрикитом Ca2(SO4)(CO3) 4H2O. Рапидкрикит образует радиально-лучистые сростки игольчатых кристаллов длиной до 200 мкм. Источником серы, по мнению авторов, являются локально развитые прослои гипса в перекрывающих известняки некарстующихся породах. Это вторая в мире находка рапидкрикита в обстановке спелеокриоминералогенеза и первая находка данного минерала в карстовых полостях на территории России.
The morphology and mineral composition of cryogenic formations of the Malaya Nizhneudinskaya Cave have been studied by electron microscopy and X-ray powder diffraction. This cave is confined to permafrost. The temperature in the cave is near zero all year round, as a result of which ice formations are widely developed in the cave. When solution freezes, and the subsequent partial evaporation of ice occurs, a cryogenic residue composed of gypsum, calcite, and a rare mineral rapidcreekite Ca2(SO4)(CO3)·4H2O is formed. Rapidcreekite forms radial-radiant aggregates of acicular crystals of up to 200 μm in length. In our opinion, the source of sulfur is represented by the locally developed interlayers of gypsum in the non-karsting rocks overlaying the limestones. This is the second finding of rapidcreekite in the speleo-cryomineralogenesis environment in the world and the first discovery of this mineral in the caves in Russia.
CHARACTERISTICS OF GLACIAL FEEDING OF RIVERS
Authors: КОНОВАЛОВ В.Г. 
Published: September 2024

Метод регионального расчета гидрологического режима оледенения включает определение многолетних изменений ледникового стока и ледникового питания в речных бассейнах Северного полушария. Информационной основой для гидрологических и гляциологических расчетов служили: данные мониторинга параметров оледенения в бассейне р. Рона за 1971-2016 гг.; многолетние измерения осадков и температуры воздуха на метеорологических станциях, расположенных на территории Швейцарии. Установлено, что результаты линейной экстраполяции пространственно-временных изменений высотно-площадных характеристик классифицированных совокупностей ледников в речных бассейнах являются достаточной входной информацией для расчета гидрологического режима оледенения. Адекватное описание процесса формирования внутригодового и многолетнего ледникового питания рек должно учитывать различия в абляции, зависящие от пяти типов деятельной поверхности ледников и их высотно-площадных характеристик. Получены удовлетворительные абсолютные и относительные оценки отклонений между измеренным стоком и суммой осадков, испарения и ледникового питания в верховье р. Рона, гидропост Порт-дю-Се, в течение 1971-2010 гг., а также между измеренными и рассчитанными объемами годовых осадков в бассейне р. Рона за 1971-2016 гг.
The elaborated method of regional calculation of the hydrological regime of glaciation includes determination of long-term changes in glacial runoff and glacial feeding in river basins. For the Rhone River basin, monitoring data on glaciation parameters over the period of 1971-2016 and long-term data on precipitation and air temperature at weather stations of Switzerland were used for hydrological and glaciological calculations. The results of linear extrapolation of spatiotemporal changes in the altitude-area characteristics of the classified groups of glaciers proved to be sufficient for calculating the hydrological regime of glaciation. An adequate description of seasonal and long-term glacial feeding of rivers should take into account spatiotemporal variations in the ablation of glaciers depending on the five types of active glacier surface and their altitude-area characteristics. Satisfactory absolute and relative estimates of differences between the measured runoff and the amount of precipitation, evaporation, and glacial feeding in the upper Rhone River in 1971-2010 (Porte du Scex gauging station), as well as between the measured and calculated annual precipitation in the Rhone River basin for 1971-2016, were obtained.
MOULINS: FORMATION AND SIGNIFICANCE
Authors: МАВЛЮДОВ Б.Р. 
Published: September 2024

На основе собственных данных и литературных источников автором рассмотрены причины и условия формирования и изменения ледниковых колодцев. Ледниковые колодцы могут формироваться выше уровня воды в ледниковых трещинах в толще льда и не могут образовываться ниже уровня воды. Цилиндрическая форма ледниковых колодцев связана с разбрызгиванием водных струй на некоторой глубине от поверхности ледника. Рассмотрены вопросы, связанные с разными механизмами образования колодцев, их глубиной, возрастом, колебаниями уровня воды. Показана возможная связь ледниковых колодцев с внутренней дренажной системой ледников. Изучена связь колодцев с надвигами в толще льда, поскольку имеются ледники, у которых вода через колодцы до ложа не проникает.
The reasons and conditions for the formation and change of moulins are considered on the base of author’s own data and on published data. Moulins can form above the water level in crevasses in the ice column and cannot form below the water level. The cylindrical shape of moulins is associated with the spraying of water jets at a certain depth from glacier surface. Questions related to different mechanisms of moulin formation, their depth, age, water level fluctuations are considered. A possible connection between moulins and the internal drainage system of glaciers is shown. Since there are glaciers in which water does not penetrate to the bed through moulins, the question of the connection between moulins and thrusts in the ice thickness is being considered.
DESIGN OF FIELD EXPERIMENTS FOR SUBSTANTIATION OF PERMAFROST MONITORING TECHNOLOGY
Authors: ГЛИНСКИХ В.Н. , ФЕДОСЕЕВ А.А. , НИКИТЕНКО М.Н. , МИХАЙЛОВ И.В. , БУХТИЯРОВ Д.А. 
Published: September 2024

С целью обоснования технологии мониторинга многолетнемерзлых пород проведены теоретический анализ и моделирование полевых экспериментов высокоразрешающего геофизического метода импульсного электромагнитного зондирования. Для выбора оптимальных параметров зондирующей системы определена зависимость регистрируемой электродвижущей силы от расстояния между источником и приемником сигналов. На основе измерений температуры на геофизическом полигоне и выявленной зависимости между удельным электрическим сопротивлением и температурой рассчитаны вариации электросопротивлений приповерхностных супесей и суглинков за период с конца января по начало апреля 2022 г. Прослежена динамика изменения границы между сезонномерзлыми и нижележащими породами. С использованием рассчитанных по измеренной температуре электросопротивлений выполнено численное моделирование электродвижущей силы для установления зависимости сигналов от перемещения границы вследствие промерзания. Предложены подходы к верификации полученных результатов.
The work is aimed at the theoretical development and modeling of field experiments for a high-resolution geophysical technique of transient electromagnetic sounding in order to substantiate a permafrost monitoring technology. To select the optimal parameters of the sounding system, we established the dynamics of changes in the registered electromotive force in terms of the distance between the signal transmitter and receiver. Based on field temperature measurements at the geophysical test site and the elucidated interrelation between the electrical resistivity and temperature values, we calculated the variations in the resistivity of the near-surface loams and clay loams for the period late January - early April 2022. The dynamics of changes in the boundary between seasonally frozen and underlying rocks was traced. Using the resistivity values calculated from the measured temperatures, we carried out numerical modeling of the electromotive force amplitude to identify the dependence of the signals on the shift of the boundary due to freezing. In addition, approaches were proposed to verification of the results obtained.
ON THE 90TH ANNIVERSARY OF PROFESSOR LEV NIKOLAEVICH KHRUSTALEV
Authors: ЕМЕЛЬЯНОВА Л.В. 
Published: September 2024

Отражены основные этапы научной и педагогической деятельности Л.Н. Хрусталева, одного из выдающихся ученых в области инженерного мерзлотоведения, заслуженного изобретателя Коми АССР, заслуженного деятеля науки Российской Федерации, доктора технических наук, заслуженного профессора Московского государственного университета имени М.В. Ломоносова.
This paper describes the milestones in the scientific and pedagogical activity of one of the outstanding scientists in the field of permafrost engineering L.N. Khrustalev, Honored Inventor of the Komi ASSR, Merited Scientist of the Russian Federation, Doctor of Technical Sciences, Honored Professor of Lomonosov Moscow State University.
Vaccine Completion and Timeliness Among Children in the Military Health System: 2010–2019
Authors: Romano Celeste J. , Burrell Monica , Bukowinski Anna T. , Hall Clinton , Gumbs Gia R. , Conlin Ava Marie S. , Ramchandar Nanda 
Published: September 2024

OBJECTIVE
Few studies have evaluated pediatric vaccination coverage in the Military Health System, although some evidence suggests lower than ideal coverage. This study assessed vaccine completion and timeliness among military dependents through age 24 months.

METHODS
Children born at military hospitals from 2010 through 2019 were identified using Department of Defense Birth and Infant Health Research program data. Vaccine completion and timeliness were assessed for diphtheria, tetanus, and pertussis; polio; measles, mumps, and rubella; hepatitis B; Haemophilus influenzae type b; varicella; and pneumococcal conjugate individually and as a combined 7-vaccine series; rotavirus was assessed separately. Modified Poisson regression models were used to calculate risk ratios (RRs) and 95% confidence intervals (CIs) for noncompletion and delays, adjusting for demographic characteristics.

RESULTS
Of 275 967 children, 74.4% completed the combined 7-vaccine series, and 36.2% of those who completed the series had delays. Completion peaked at 78.7% among children born in 2016 and 2017. Among all vaccines, completion was lowest for rotavirus (77.5%), diphtheria, tetanus, and pertussis (83.1%), Haemophilus influenzae type b (86.6%), and pneumococcal conjugate (88.4%). Risk for noncompletion was higher among children born to younger pregnant parents (adjusted RR = 1.33; 95% CI = 1.27–1.40) and with a well-child care location change (adjusted RR = 1.10; 95% CI = 1.09–1.12). Risk for delays paralleled that for noncompletion.

CONCLUSIONS
Vaccine completion and timeliness generally improved among military children, but greater noncompletion of vaccine series with more versus fewer doses and disparities for younger and mobile service members suggest system barriers remain.
АНАЛИЗ И ОЦЕНКА ЭФФЕКТИВНОСТИ ЭКОНОМИЧЕСКОЙ ПОЛИТИКИ В СТРОИТЕЛЬНОМ КОМПЛЕКСЕ РФ
Authors: В.А. Басалаев 
Published: September 2024

В статье рассматриваются содержание и особенности экономической политики в строительном комплексе Российской Федерации. Анализируются основные проблемы развития строительной сферы, методы и инструменты экономической политики, направленные на их решение. Проведена оценка эффективности экономической политики в строительстве, выявлены ключевые направления ее повышения.
The article examines the content and features of economic policy in the construction complex of the Russian Federation, analyzes the main problems of the development of the construction sector, methods and tools of economic policy aimed at solving them. An assessment of the effectiveness of economic policy in construction has been carried out, and key areas for its improvement have been identified.
STUDY OF SOCIAL-EMOTIONAL DEVELOPMENT: THE IMPACT OF FATHERLESSNESS
Authors: Kuswanto Cahniyo Wijaya , Meriyati Meriyati , Pratiwi Dona Dinda , Sakinah Dini 
Published: September 2024

This problem is motivated by the fact that there are still many children who are fatherless because of divorced parents and fathers who are not present in the development of their social and emotional development have not yet developed. This study aims to find out how the impact of fatherlessness on the social and emotional development of children who have divorced parents, and children whose fathers are not present in development. The subjects of this research were 10 single parents/transferential care parents for early childhood children aged 5-6 years. The results of the research on the impact of fatherlessness on social- emotional development who experienced divorced parents had social-emotional development that was not well developed, children were still able to interact with other people but had a shy, quiet, introverted nature, preferring to be alone. the impact of fatherlessness on the social-emotional development of divorced parents has a social-emotional development that begins to develop the ability to interact with the environment and be cooperative. For the ability to interact with the surrounding environment, to be cooperative, to be tolerant, and to be empathetic well even though it is only limited to family members and closest friends. The findings that researchers found on the impact of fatherlessness on social-emotional development occurred in fatherless children, because of divorced parents and fathers who were not present in development. Children who experience divorced parents are more likely to be hampered by aspects of social-emotional development compared to fatherless children who are missing their parents’ role during the development process.<p> </p>
The Synergistic Health Threats of State Laws Targeting Marginalized Groups in the United States
Authors: Underhill Kristen , Earnshaw Valerie A. , Nelson Kimberly M. 
Published: September 2024

Discriminatory state laws have deleterious effects on the health of socially marginalized groups. Health care clinicians, institutions, researchers, and research funders have tended to view different discriminatory laws in isolation, focusing on particular issues or groups. In contrast, intersectionality calls attention to the overlapping and synergistic systems of oppression that discriminatory legislation promotes or upholds, warranting an integrated analysis of these laws. In this analytic essay, we assess discriminatory state laws simultaneously and discuss their implications for health care clinicians, institutions, and researchers. We present a multifunctional model of law and population health that describes how discriminatory law affects health outcomes among marginalized groups. We then draw on publicly available legislation trackers to identify 30 states that have enacted legislation since 2020 that targets Black people and other people of color; lesbian, gay, bisexual, and queer people; transgender and nonbinary people; and women and other birthing people. Finally, we call for a coordinated, multilateral, and forceful effort by health care professionals, institutions, researchers, and research funders to counter these laws and address their predictable health consequences. ( Am J Public Health. 2024;114(12):1335–1343. https://doi.org/10.2105/AJPH.2024.307830 )
Coupled role of climate and tectonics in the deposition of the late Quaternary sedimentary sequence in the southern margin of the central Ganga Plain, India
Authors: Yadav Mukesh , Shukla U.K. , Gurumurthy G.P. , Ali Sajid , Kumar Kamlesh , Sharma Anupam 
Published: September 2024

ABSTRACT
The Ganga Plain’s sedimentation is primarily controlled by Himalayan tectonics, variations in monsoon intensity, and glacier size. However, the significance of intrabasinal tectonics, which is an interplay of the Himalaya tectonics and basement tectonic configuration of the Ganga Plain, in comprehending the late Quaternary Ganga Plain sedimentation remains unclear. In this study, the sediment provenance and extent of weathering experienced by the sediments are studied using the mineralogical and geochemical (major, trace, and rare earth elements) composition of a sedimentary cliff sequence exposed at the Ramnagar locality near the cratonic peripheral bulge in the southern Ganga Plain. In the Ramnagar cliff sediment section, two sediment packages, designated SP-A and SP-B, are identified based on mineralogy, texture, and geochemistry. These packages of sediments show mild chemical weathering and distinct geochemical compositions. The lower part (SP-A) of the Ramnagar cliff section is characterized by higher contributions from mafic sources (pyroxene, feldspar, and mica as dominant minerals), while the upper part (SP-B) is predominately derived from felsic sources (mica and feldspar as dominant minerals), which are supplied via the peninsular and the Himalayan rivers, respectively. The southern part of the central Ganga Plain shows evidence of a shift in the sediment provenance from mafic to felsic source rock at 40 ka. This study demonstrates how weathering and sedimentation are controlled by both regional tectonics and climate in the southern margin of the central Ganga Plain.
A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its role in cholesterol metabolism
Authors: Oh Kwangyeon , Yuk Minju , Yang Soyoun , Youn Jiyeong , Dong Qian , Wang Zhaoming , Song Nan 
Published: September 2024

Abstract

High-sensitivity C-reactive protein (hsCRP) is a representative biomarker of systemic inflammation and is associated with numerous complex diseases. To explore the biological pathways and functions underlying chronic inflammation, we conducted a genome-wide association study (GWAS) and several post-GWAS analyses of the hsCRP levels. This study was performed on data from 71,019 Koreans and is one of the largest East Asian studies. Overall, 69 independent single nucleotide polymorphisms (SNPs) were identified, including 12 novel variants located within SHE, RP11-740C1.2, FCRL6, STEAP1B, AC002480.5, TOMM7, SPPL3, RP11-216P16.6, RP11-209K10.2, CTC-490E21.12, CYP2F2P, CBLC, and PVRL2. The implicated genes and pathways are primarily involved in cholesterol metabolism and the immune response. A phenome-wide association study was performed based on a polygenic risk score constructed using 69 hsCRP-associated SNPs. Notably, the alleles associated with higher hsCRP levels appeared to be associated with lower low-density lipoprotein cholesterol levels (P=1.69 × 10-33, β=-1.47). Our findings provide evidence of a link between hsCRP and cholesterol as well as the clinical importance of hsCRP. Specifically, we suggest that genetically determined hsCRP levels may be useful for predicting the potential risk of cardiovascular or other diseases related to lipid metabolism.
Research on the spatial aggregation characteristics of medical and health facilities in the Yangtze River Delta urban agglomeration based on POI
Authors: Yumeng Wang , Qunshan Tao 
Published: September 2024

Abstract

Understanding the spatial layout structure and its influencing factors on the supply of medical and health resources in the Yangtze River Delta urban agglomeration is crucial for promoting regional integration and achieving balanced inter-regional medical service development. This study investigates the Yangtze River Delta urban agglomeration using kernel density analysis and average nearest neighbor distance analysis. By utilizing Gaode open-source POI data from 2023, the spatial aggregation characteristics of medical and health facilities in the region are examined. Additionally, the geographical detector method is employed to explore the factors influencing regional imbalance, focusing on population density, traffic accessibility, policy inclination, and residents' income levels. The findings reveal a clear spatial clustering of medical and health facilities, with the lowest clustering observed in professional public health institutions. Shanghai serves as the core of clustering, with notable agglomeration in all metropolitan areas, while the Anhui urban agglomeration shows weaker overall clustering. The spatial clustering of medical and health facilities results from the interaction of multiple factors, with combined factors having a more significant impact than single factors. Policy inclination emerges as the most significant single factor affecting clustering. These results offer valuable insights for the sustainable and healthy development of the medical industry in the Yangtze River Delta urban agglomeration and provide data support for fostering coordinated regional integration.
Synergic action of microRNAs and Wnts delivered by motor neuron EVs in promoting AChR clustering
Authors: Agostini Rachele , Ceccaroli Paola , Polidori Emanuela , Ferracin Manuela , Pace Ilaria , Maggio Serena , Cioccoloni Andrea , Battistelli Michela , Matacchione Giulia , Sbriscia Matilde , Olivieri Fabiola , Cesca Fabrizia , Stocchi Vilberto , Guescini Michele 
Published: September 2024

Abstract

Background
The neuromuscular junction (NMJ) establishment occurs through complex communication events between motor neurons and muscle fibers; however, the molecular mechanisms leading to NMJ formation have yet to be fully elucidated. Little is known about the significance of extracellular vesicles (EVs) in mediating the interaction between motor neurons and muscle fiber in the NMJ establishment; this study investigates the role of motor neuron-derived EVs during aneural pre-patterning.
Methods
NSC-34 cells have been used as a model of motor neurons; EVs have been isolated during neurite development using a serial ultracentrifugation protocol specifically adjusted to isolate large and small EVs. Subsequently, isolated EVs were quantified through Nanoparticles Tracking Assay and characterized by Western Blot and TEM analysis. Small RNA seq analysis of the miRNAs loaded into EVs has been validated with specific quantitative RT-PCR assays. Subsequently, online web resources predicted the miRNA downstream targets to be involved in Wnt signaling, and their modulation in response to EV treatment was investigated.
Results
NGS analysis of small RNAs carried by NSC-34-derived EVs identified a total of 245 microRNAs, most of which are up-regulated in NSC-34 cells and EVs, along with neurite stretching. Prediction analysis highlighted that many of these miRNAs synergically target the Wnt signaling pathway. Moreover, we found that NSC-34-derived EVs carry Wnts, such as Wnt11, Wnt4 and Wnt3a. Since several studies pointed out the role of the Wnt-associated signaling network in NMJ formation, we investigated the role of EVs in muscle pre-patterning and demonstrated that EV administration to myotubes increases acetylcholine receptor (AChR) cluster formation as revealed by immunofluorescence staining with α-bungarotoxin.
Moreover, myotube treatment with NSC-34-derived EVs led to GSK3β and JNK phosphorylation, followed by β-catenin nuclear translocation, suggesting that neuron-derived EVs can induce AChR clustering through Wnt pathway activation.
Conclusion
These data demonstrate that EVs released from differentiated motor neurons carry multimodal signals, miRNAs, and Wnts, which can stimulate AChR clustering in myotubes, a fundamental preparatory stage for NMJ formation. These new data highlight that EVs may play a role in the NMJ establishment and function under physiological and pathological conditions, particularly neurodegenerative diseases.