bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre‐game perceived wellness highly associates with match running performances during an international field hockey tournament
Authors: Ihsan Mohammed , Tan Frankie , Sahrom Sofyan , Choo Hui Cheng , Chia Michael , Aziz Abdul Rashid 
Published: April 2017

AbstractThis study examined the associations between pre‐game wellness and changes in match running performance normalised to either (i) playing time, (ii) post‐match RPE or (iii) both playing time and post‐match RPE, over the course of a field hockey tournament. Twelve male hockey players were equipped with global positioning system (GPS) units while competing in an international tournament (six matches over 9 days). The following GPS‐derived variables, total distance (TD), low‐intensity activity (LIA; <15 km/h), high‐intensity running (HIR; >15 km/h), high‐intensity accelerations (HIACC; >2 m/s2) and decelerations (HIDEC; >−2 m/s2) were acquired and normalised to either (i) playing time, (ii) post‐match RPE or (iii) both playing time and post‐match RPE. Each morning, players completed ratings on a 0–10 scale for four variables: fatigue, muscle soreness, mood state and sleep quality, with cumulative scores determined as wellness. Associations between match performances and wellness were analysed using Pearson's correlation coefficient. Combined time and RPE normalisation demonstrated the largest associations with Δwellness compared with time or RPE alone for most variables; TD (r = −0.95; −1.00 to −0.82, p = .004), HIR (r = −0.95; −1.00 to −0.83, p = .003), LIA (r = −0.94; −1.00 to −0.81, p = .026), HIACC (r = −0.87; −1.00 to −0.66, p = .004) and HIDEC (r = −0.90; −0.99 to −0.74, p = .008). These findings support the use of wellness measures as a pre‐match tool to assist with managing internal load over the course of a field hockey tournament.Highlights
Fixtures during international field hockey tournaments are typically congested and impose high physiological demands on an athlete. To minimise decrements in running performance over the course of a tournament, measures to identify players who have sustained high internal loads are logically warranted.
The present study examined the association between changes in simple customised psychometric wellness measures, on changes in match running performance normalised to (i) playing time, (ii) post‐match RPE and (iii) playing time and post‐match RPE, over the course of a field hockey tournament.
Changes in match running performance were better associated to changes in wellness (r = −0.87 to −0.95), when running performances were normalised to both time and RPE compared with time or RPE alone.
The present findings support the use of wellness measures as a pre‐match tool to assist with managing internal load over the course of a field hockey tournament. Improved associations between wellness scores and match running performances were evident, when running variables were normalised to both playing time and post‐match RPE.
Explaining the isotope effect on heat transport in L-mode with the collisional electron-ion energy exchange
Authors: Schneider P.A. , Bustos A. , Hennequin P. , Ryter F. , Bernert M. , Cavedon M. , Dunne M.G. , Fischer R. , Görler T. , Happel T. , Igochine V. , Kurzan B. , Lebschy A. , McDermott R.M. , Morel P. , Willensdorfer M. 
Published: April 2017

Abstract
In ASDEX Upgrade (AUG), the normalised gyroradius

ρ

⋆

was varied via a hydrogen isotope scan while keeping other dimensionless parameters constant. This was done in L-mode, to minimise the impact of pedestal stability on confinement.
Power balance and perturbative transport analyses reveal that the electron heat transport is unaffected by the differences in isotope mass. Nonlinear simulations with the Gene code suggest that these L-mode discharges are ion temperature gradient (ITG) dominated. The different gyroradii due to the isotope mass do not necessarily result in a change of the predicted heat fluxes. This result is used in simulations with the Astra transport code to match the experimental profiles. In these simulations the experimental profiles and confinement times are reproduced with the same transport coefficients for hydrogen and deuterium plasmas. The mass only enters in the energy exchange term between electrons and ions.
These numerical observations are supported by additional experiments which show a lower ion energy confinement compared to that of the electrons. Additionally, hydrogen and deuterium plasmas have a similar confinement when the energy exchange time between electrons and ions is matched.
This strongly suggests that the observed isotope dependence in L-mode is not dominated by a gyroradius effect, but a consequence of the mass dependence in the collisional energy exchange between electrons and ions.
Monitoring performance using synthetic data for induced microseismicity by hydrofracking at the Wysin site (Poland)
Authors: López-Comino J.A. , Cesca S. , Kriegerowski M. , Heimann S. , Dahm T. , Mirek J. , Lasocki S. 
Published: April 2017

AbstractIdeally, the performance of a dedicated seismic monitoring installation should be assessed prior to the observation of target seismicity. This work is focused on a hydrofracking experiment monitored at Wysin, NE Poland. A microseismic synthetic catalogue is generated to assess the monitoring performance during the pre-operational phase, where seismic information only concerns the noise conditions and the potential background seismicity. Full waveform, accounting for the expected spatial, magnitude and focal mechanism distributions and a realistic local crustal model, are combined with real noise recording to produce either event based or continuous synthetic waveforms. The network detection performance is assessed in terms of the magnitude of completeness (Mc) through two different techniques. First, we use an amplitude threshold, taking into the ratio among the maximal amplitude of synthetic waveforms and station-dependent noise levels, for different values of signal-to-noise ratio. The detection probability at each station is estimated for the whole data set and extrapolated to a broader range of magnitude and distances. We estimate an Mc of about 0.55, when considering the distributed network, and can further decrease Mc to 0.45 using arrays techniques. The second approach, taking advantage on an automatic, coherence-based detection algorithm, can lower Mc to ∼ 0.1, at the cost of an increase of false detections. Mc experiences significant changes during day hours, in consequence of strongly varying noise conditions. Moreover, due to the radiation patterns and network geometry, double-couple like sources are better detected than tensile cracks, which may be induced during fracking.
Asynchronous automated electronic laboratory result notifications: a systematic review
Authors: Slovis Benjamin H , Nahass Thomas A , Salmasian Hojjat , Kuperman Gilad , Vawdrey David K 
Published: April 2017

AbstractObjectiveTo systematically review the literature pertaining to asynchronous automated electronic notifications of laboratory results to clinicians.MethodsPubMed, Web of Science, and the Cochrane Collaboration were queried for studies pertaining to automated electronic notifications of laboratory results. A title review was performed on the primary results, with a further abstract review and full review to produce the final set of included articles.ResultsThe full review included 34 articles, representing 19 institutions. Of these, 19 reported implementation and design of systems, 11 reported quasi-experimental studies, 3 reported a randomized controlled trial, and 1 was a meta-analysis. Twenty-seven articles included alerts of critical results, while 5 focused on urgent notifications and 2 on elective notifications. There was considerable variability in clinical setting, system implementation, and results presented.ConclusionSeveral asynchronous automated electronic notification systems for laboratory results have been evaluated, most from &gt;10 years ago. Further research on the effect of notifications on clinicians as well as the use of modern electronic health records and new methods of notification is warranted to determine their effects on workflow and clinical outcomes.
Treatment of Intracranial Aneurysms With the SILK Embolization Device in a Multicenter Study. A Retrospective Data Analysis
Authors: Pumar José Manuel , Banguero Alexandra , Cuellar Hugo , Guimaraens Leopoldo , Masso Javier , Miralbes Salvador , Blanco-Ulla Miguel , Vazquez-Herrero Fernando , Souto Miguel , Gelabert-Gonzalez Miguel 
Published: April 2017

Abstract

BACKGROUND
Flow-diverter technology has become an important stent-based embolization tool in the treatment of complex cerebrovascular pathology. We report here the experience of 4 Spanish centers with using the SILK flow-diverter (SFD) device.

OBJECTIVE
To evaluate the safety and efficacy of using the SFD in the endovascular treatment of intracranial aneurysms with complex morphology.

METHODS
We retrospectively examined a prospectively maintained database of patients treated with SFD devices between July 2008 and December 2013 at 1 of 4 institutions in Spain. Data regarding patient demographics, aneurysm characteristics, and technical procedure were analyzed. Angiographic and clinical findings were recorded during the procedure and at 12 months postoperatively.

RESULTS
A total of 175 SFD devices were implanted in 157 patients (women/men: 119/38; mean, median, and range of age: 56.2, 56.7, and 19-80 years, respectively), who were treated in a delayed manner (3-6 months from the event) for 180 aneurysms (165 unruptured and 15 ruptured). Adverse events (acute and delayed) were observed in 28.7% of cases (45/157), and most were resolved (19.1%; 30/157). Six months after the procedure, total morbidity and mortality were 9.6% (15/157) and 3.2% (5/157), respectively. Long-term imaging follow-up showed complete occlusion, neck remnants, and residual aneurysm in 78.1% (100/128), 14.0% (18/128), and 7.8% (10/128) of cases, respectively.

CONCLUSIONS
The SFD device is an effective tool for the treatment of challenging aneurysms, and allows complete occlusion within a year of the procedure in most patients, with morbidity and mortality comparable to those previously reported for similar devices.
Radiosurgery for Unruptured Brain Arteriovenous Malformations: An International Multicenter Retrospective Cohort Study
Authors: Ding Dale , Starke Robert M. , Kano Hideyuki , Lee John Y.K. , Mathieu David , Pierce John , Huang Paul , Missios Symeon , Feliciano Caleb , Rodriguez-Mercado Rafael , Almodovar Luis , Grills Inga S. , Silva Danilo , Abbassy Mahmoud , Kondziolka Douglas , Barnett Gene H. , Lunsford L. Dade , Sheehan Jason P. 
Published: April 2017

Abstract

BACKGROUND: The role of intervention in the management of unruptured brain arteriovenous malformations (AVM) is controversial.

OBJECTIVE: To analyze in a multicenter, retrospective cohort study, the outcomes following radiosurgery for unruptured AVMs and determine predictive factors.

METHODS: We evaluated and pooled AVM radiosurgery data from 8 institutions participating in the International Gamma Knife Research Foundation. Patients with unruptured AVMs and ≥12 mo of follow-up were included in the study cohort. Favorable outcome was defined as AVM obliteration, no postradiosurgical hemorrhage, and no permanently symptomatic radiation-induced changes.

RESULTS: The unruptured AVM cohort comprised 938 patients with a median age of 35 yr. The median nidus volume was 2.4 cm3, 71% of AVMs were located in eloquent brain areas, and the Spetzler-Martin grade was III or higher in 57%. The median radiosurgical margin dose was 21 Gy and follow-up was 71 mo. AVM obliteration was achieved in 65%. The annual postradiosurgery hemorrhage rate was 1.4%. Symptomatic and permanent radiation-induced changes occurred in 9% and 3%, respectively. Favorable outcome was achieved in 61%. In the multivariate logistic regression analysis, smaller AVM maximum diameter (P = .001), the absence of AVM-associated arterial aneurysms (P = .001), and higher margin dose (P = .002) were found to be independent predictors of a favorable outcome. A margin dose ≥ 20 Gy yielded a significantly higher rate of favorable outcome (70% vs 36%; P < .001)

CONCLUSION: Radiosurgery affords an acceptable risk to benefit profile for patients harboring unruptured AVMs. These findings justify further prospective studies comparing radiosurgical intervention to conservative management for unruptured AVMs.
Food labeling issues in patients with severe food allergies: solving a hamlet-like doubt
Authors: Fierro Vincenzo , Di Girolamo Francesco , Marzano Valeria , Dahdah Lamia , Mennini Maurizio 
Published: April 2017

Purpose of review
We review the laws on labeling in the international community, the difficulties they pose to the food manufacturers to prepare the food labels and the methodologies to determine the concentration of potential allergens in foods.

Recent findings
European Food Safety Authority and International Life Sciences Institute Europe are evaluating strategies to identify the threshold level of allergen that can trigger a reaction in individuals. The most used techniques to detect the presence of protein in food are Enzyme-linked immunosorbent assay, polymerase chain reaction and real time polymerase chain reaction. Researchers are now trying to apply proteomics to estimate the amount of protein within the food.
In order to protect the health of consumers, the Codex Alimentarius Commission updates constantly the list of allergens. In response to these regulations, some industries have also added some precautionary allergen labeling (PAL). It was generally agreed that PAL statements needed to be visible, simple, and safe. It was suggested that PAL be standardized, an action that would occur if the ‘Voluntary Incidental Trace Allergen Labelling’ process was made mandatory.

Summary
So far, no laboratory technique is able to reassure the consumers about the composition of foods found on the packaging. International authorities produced increasingly stringent laws, but more is still to do.
Early results of partial capitate shortening osteotomy in management of Kienböck disease
Authors: Singer Mohamed S. , Essawy Osama M. , Farag Hosam E. 
Published: April 2017

Background:
Capitate shortening is the best decompression procedure in the management of Kienböck’s disease in patients with ulnar neutral or positive variance, although carpal collapse develops inevitably. The current study was to report our experience in partial capitate shortening osteotomy as an alternative procedure.

Methods:
This was a prospective study of 20 patients with Lichtman stage II and IIIa Kienböck’s disease managed by partial capitate shortening osteotomy.

Results:
At final follow-up (average 36.5 mo), visual analog pain scores improved significantly postoperatively to 3.3. Flexion and extension improved from 62% (±17%) and 52% (±21%) preoperatively to 63% (±13%) and 68% (±13) postoperatively, respectively. The power grip improved significantly from 49% (±16%) to 63% (±12%) postoperatively. The average quick Disability of the Arm Shoulder and Hand Score improved from 60.8(±13.8) to 38.3(±13.9) postoperatively.

Conclusions:
Partial capitate shortening is a simple and effective procedure for the management of ulnar neutral or ulnar positive Kienböck’s disease before the onset of radiocarpal arthrosis without violation of scaphocapitate joint thus avoiding carpal collapse that follows complete capitate shortening.

Type of Study/Level of Evidence:
Therapeutic IV.
Curve Modulation and Apex Migration Using Shilla Growth Guidance Rods for Early-onset Scoliosis at 5-Year Follow-up
Authors: Wilkinson John T. , Songy Chad E. , Bumpass David B. , McCullough Francis L. , McCarthy Richard E. 
Published: April 2017

Background:
The Shilla procedure was designed to correct and control early-onset spinal deformity while harnessing a child’s remaining spinal growth. It allows for controlled axial skeletal growth within the construct, avoiding the need for frequent surgeries to lengthen implants. We hypothesized that curve characteristics evolve over time after initial apex fusion and placement of the Shilla implants. The purpose of this study was to identify trends in curve evolution after Shilla implantation and understand how these changes influence ultimate outcome.

Methods:
A single-center, retrospective review of all patients with Shilla implants in place for ≥5 years yielded 21 patients. Charts and radiographs were reviewed to compare coronal curve characteristics preoperatively, postoperatively, and at last follow-up to note changes in the apex of the primary curve. Also noted were the development of adjacent compensatory curves, the overall vertical spinal growth, and the need for definitive spinal fusion once skeletal maturity was reached.

Results:
Of the 21 patients, the curve apex migrated caudally in 12 patients (57%) and cephalad in 1 patient (5%), with a mean migration of 2.7 vertebral levels. Two patients (10%) developed new, significant compensatory curves (1 caudal and 1 cephalad). All patients demonstrated spinal growth in T1-S1 length following index surgery (mean, 45 mm). At skeletal maturity, 10 patients underwent definitive posterior spinal fusion and instrumentation, and 3 underwent implant removal alone.

Conclusions:
This study constitutes the longest follow-up of Shilla patients evaluating curve and implant behavior. Results of this review suggest that the apex of the fused primary curve shifts in approximately 62% of patients, with nearly all of these (92%) involving a distal migration. Compensatory curves did develop after Shilla placement as well. Overall, these findings represent adding-on distal to the apex after Shilla instrumentation rather than a crankshaft phenomenon about the apex. A better understanding of spinal growth mechanics and outcomes after Shilla placement may improve our ability to appropriately select patients and instrumentation levels.

Level of Evidence:
Level III.
VEPTR: Are We Reducing Respiratory Assistance Requirements?
Authors: Nossov Sarah B. , Curatolo Evan , Campbell Robert M. , Mayer Oscar H. , Garg Sumeet , Cahill and Patrick J. 
Published: April 2017

Background:
The assisted ventilation rating (AVR) indicates the degree of external respiratory support required in children with thoracic insufficiency syndrome (TIS) and early onset scoliosis. For skeletally immature patients with TIS, the vertical expandable prosthetic titanium rib (VEPTR) device can be used to improve lung volume and growth. We hypothesized that patients who underwent early thoracic reconstruction by VEPTR treatment had an improved respiratory status.

Methods:
Preoperative and postoperative AVR ratings were prospectively collected in a multicenter study group and compared to determine change after VEPTR treatment. Patients under 10 years of age at initial implant with minimum of 2-year follow-up data were included. Patients were excluded if there were incomplete data or if initial AVR was normal (breathing on room air). Statistical analysis was performed on groups which had stable, declined, and improved AVR at final follow-up.

Results:
Database search yielded 77 patients with initial abnormal AVR. Average follow-up was 5.6 years. The most frequent primary diagnoses were congenital scoliosis (n=14) and spinal muscular atrophy (n=14). In total, 19 (24%) demonstrated improvement, 9 (12%) patients deteriorated, and 49 (64%) remained at the same level. The average preoperative major curve in those with improvement (58.4 degrees) and those with no change (63.5 degrees) was less than in those with deterioration (85.5 degrees) (P=0.014). The average age in years at implant of those with improvement (4) was less than those declined (6.7) and those with no change (5.5). In total, 16 (84.2%) of those that improved had a normal AVR and did not require respiratory support at last follow-up.

Conclusions:
There is evidence that a subset of patients with early onset scoliosis and TIS who received early thoracic reconstruction with VEPTR treatment show complete resolution of pulmonary support at final follow-up. In total, 89% of 79 patients did not experience respiratory deterioration. A total of 24% (n=19) had a positive change with over 84% (n=16) of this group no longer requiring support.

Level of Evidence:
Level III—prognostic.
Evaluation of Gabapentin and Clonidine Use in Children Following Spinal Fusion Surgery for Idiopathic Scoliosis: A Retrospective Review
Authors: Choudhry Dinesh K. , Brenn B. Randall , Sacks Karen , Shah Suken 
Published: April 2017

Background:
Opioids are the mainstay of therapy for pain relief following posterior spinal fusion (PSF) surgery. Various adjunctive medications are being used to augment analgesia and to reduce opioid-related side effects. At our institution, we have sequentially added 2 adjuncts to a standard morphine patient-controlled analgesia (PCA) regimen. The goal of our study was to evaluate pain control and the benefit of gabapentin and the combination of gabapentin and clonidine, whereas morphine PCA was in use in children following PSF surgery.

Methods:
Following Institutional Review Board approval, data were collected retrospectively from the charts of 127 patients who underwent PSF for idiopathic scoliosis. Children were divided into the 3 following groups: group P, morphine PCA only (42 patients), group G, morphine PCA+gabapentin (45 patients), and group C, morphine PCA+gabapentin+clonidine (40 patients).

Results:
Addition of gabapentin to our regimen improved the outcome, but the addition of transdermal clonidine and gabapentin together were found to be significantly better in some aspects. Children in group G and C used less morphine on postoperative day 1 following surgery, had more PCA demand-free hours, were able to take orals, were able to ambulate sooner, and had a shorter hospital stay than group P. There were no differences in side effects or sedation between the 3 groups.

Conclusions:
In conclusion, additions of postoperative transdermal clonidine and perioperative oral gabapentin together were found to improve functional outcomes following PSF surgery. Group G and C had reduced opioid use and shorter hospital stay than group P. Addition of these adjuncts together was found to be better since group C patients made fewer PCA attempts to obtain morphine over the first 10-hour period postoperatively and were able to ambulate sooner than group G. The PCA pump usage pattern provides useful information about patient comfort and efficacy of adjunctive medications.

Level of Evidence:
Level II—retrospective study.