bluuebunny/crossref_metadata_2025_split huggingface dataset:
Essential Palatal Myoclonus
Authors: Pandey Bhuwan Raj , Acharya Anup , Singh Madan Mohan 
Published: June 2017

Introduction: Palatal myoclonus is a rare condition presenting with clicking sound in ear or muscle tremor in pharynx. There are two varieties: essential and symptomatic. Various treatment options exists ranging from watchful observation to botulinum toxin injection. We have not found any reported case of palatal myoclonus from our country. Here we present a case of essential palatal myoclonus managed with clonazepam.
Case report: A young female presented in Ear Nose and Throat clinic with complain of auditory click and spontaneous rhythmic movement of throat muscles for eight months. On examination, there was involuntary, rhythmic contraction of bilateral soft-palate, uvula, and base of tongue. Neurological, eye, and peripheral examination were normal. A diagnosis of essential palatal myoclonus was made. It was managed successfully with clonazepam; patient was still on low dose clonazepam at the time of making this report.
Conclusion: Essential palatal myoclonus can be clinically diagnosed and managed even in settings where MRI is not available or affordable.
Diseño de cadena de abastecimiento bajo el concepto de logística inversa para el sector manufacturero de papel en la zona centro del Valle del Cauca.
Authors: Peña Orozco Diego Leon , Bolaños Carranza Diana Fernanda , Salcedo Peláez Paola Fernanda 
Published: June 2017

Hoy en día la utilización de Productos Fuera de Uso (PFU) en la industria manufacturera de papel, ha tomado un mayor interés tanto en el ámbito de los negocios como en la investigación. Este fenómeno se ha dado gracias a la conciencia ambiental que se está estructurando en estas empresas, y también gracias al avance en la gestión de la cadena de suministro.Para la correcta recolección de los PFU, se debe diseñar una cadena de abastecimiento inversa que sea capaz de administrar o gestionar adecuadamente la recolección de estos productos, a un costo logístico menor. Dentro del diseño de la cadena de abastecimiento se tendrán en cuenta todos los componentes necesarios para la recolección del papel, tales como la localización del centro de recuperación para lo cual es necesario contar con la información de tres plantas manufactureras de papel y de centros de reciclajes ubicados en la zona centro del Valle del Cauca.
Implementación de un modelo para la representación vectorial de la actividad eléctrica del corazón en un espacio tridimensional
Authors: NIÑO NIÑO CARLOS ANDRES , Barrero Perez Jaime Guillermo , Peña Quimbayo Mauricio Javier , Infante Vivas Julián Darío 
Published: June 2017

Al implementarse una tarjeta electrónica con la cual se adquiere la información proveniente de tres canales electrocardiográficos cuasi-ortogonales entre sí, V2, aVF, D1 se obtienen los datos necesarios para representar mediante ellos la actividad eléctrica del corazón en un espacio tridimensional. El vectocardiograma representa la actividad eléctrica del corazón en forma vectorial, esta representación necesita definir el origen de coordenadas y el plano principal de proyección de las fuerzas eléctricas del corazón. Este estudio utiliza un método basado en el cálculo de momentos de inercia mecánicos para determinar la dirección correcta del vectocardiograma.
El cortometraje como herramienta innovadora para el alumnado con Altas Capacidades en Educación Primaria
Authors: Fernández del Río Ana Belén , Barreira Arias Alberto José 
Published: June 2017

El presente estudio muestra los resultados de una experiencia implementada con alumnado de Altas Capacidades de Educación Primaria utilizando el cortometraje como estrategia innovadora basada en la animación y creación audiovisual, para la mejora de sus potencialidades. Se pretende, por un lado, analizar la progresión de dichos estudiantes y, por otro, ejemplificar dicho análisis utilizando la técnica short-films, dando a conocer sus posibilidades como herramienta didáctico-pedagógica que promueva la mejora de su potencial creativo. De forma específica, se procura crear, manipular y combinar textos e imágenes de forma creativa, favorecer la adquisición de habilidades sociales, utilizar eficazmente procedimientos de búsqueda, recogida y procesamiento de la información, así como valorar los medios de comunicación social como instrumento para aprender a acceder a informaciones y experiencias. Como método de investigación se utiliza el estudio de casos y también la investigación-acción. La muestra seleccionada de carácter intencional está constituida por 12 estudiantes de Altas Capacidades de Educación Primaria. En el análisis cualitativo de los datos se utilizó el software ATLAS.ti. Tras la intervención se constata una mejora relevante en la creatividad del alumnado; así como un incremento en su motivación, destacando la adquisición y desarrollo de habilidades como el trabajo colaborativo en donde se aprenden estrategias para resolver problemas. Asimismo, habilidades interpersonales como la comunicación, el liderazgo y la capacidad de decisión.
Validity of CAVI measurements for diagnosing hypertension in middle-aged and elderly patients and correlations of these measurements with relevant factors
Authors: Qiao Aike , Song Xiaorui , Peng Kun , Du Guowei , Li Gaoyang , Chen Zhihui 
Published: June 2017

BACKGROUND: The high risk of hypertension in middle-aged and elderly people has led to the development of the cardio-ankle vascular index (CAVI), a novel predictor of cardiovascular events. OBJECTIVE: This paper aimed to determine how reliably hypertension can be diagnosed in middle-aged and elderly people by measuring CAVI. METHODS: One hundred and ninety-five subjects (69 males/126 females; mean age of 56.06 [Formula: see text] 2.08 years) were enrolled. CAVI were measured using a blood pressure and pulse monitor device. RESULTS: The CAVI was positively correlated with age, SBP, PP and PPI in the hypertension group ([Formula: see text] 0.656, 0.388, 0.445, 0.376; all [Formula: see text] 0.05). The mean CAVI was the significant difference between each age group. The ROC results showed that the best diagnostic point was 8.350, where the sensitivity was 72.2% and the specificity was 72.3%. The positive rate of the CAVI was higher than normal blood pressure for those over 60 years of age. CONCLUSION: Compared with normal blood pressure measurements, CAVI measurements are relatively reliable for predicting hypertension in those over the age of 60. More attention should be paid to the CAVI [Formula: see text] 8.350, which may be regarded as a simple and noninvasive reference index of hypertension diagnosis for middle-aged and elderly.
ChainMail based neural dynamics modeling of soft tissue deformation for surgical simulation
Authors: Zhang Jinao , Zhong Yongmin , Smith Julian , Gu Chengfan 
Published: June 2017

BACKGROUND: Realistic and real-time modeling and simulation of soft tissue deformation is a fundamental research issue in the field of surgical simulation. OBJECTIVE: In this paper, a novel cellular neural network approach is presented for modeling and simulation of soft tissue deformation by combining neural dynamics of cellular neural network with ChainMail mechanism. METHOD: The proposed method formulates the problem of elastic deformation into cellular neural network activities to avoid the complex computation of elasticity. The local position adjustments of ChainMail are incorporated into the cellular neural network as the local connectivity of cells, through which the dynamic behaviors of soft tissue deformation are transformed into the neural dynamics of cellular neural network. RESULTS: Experiments demonstrate that the proposed neural network approach is capable of modeling the soft tissues’ nonlinear deformation and typical mechanical behaviors. CONCLUSIONS: The proposed method not only improves ChainMail’s linear deformation with the nonlinear characteristics of neural dynamics but also enables the cellular neural network to follow the principle of continuum mechanics to simulate soft tissue deformation.
Sistema de manufactura reconfigurable y competitividad industrial
Authors: Ortega Jiménez César H. , Eguía Salinas Ignacio 
Published: June 2017

Este artículo ha decidido usar un modelo dinámico de competitividad de la Producción de Alto Rendimiento (High Performance Manufacturing, HPM), que presentelas condiciones actuales en el escenario industrial a nivel mundial,para la futura implementación de Sistemas de Manufactura Reconfigurable (Reconfigurable Manufacturing Systems, RMSs). Así pues, aunque los RMSs pueden ser esenciales para la mejora continua, la globalización ha hecho difícil ganar ventaja (o aún paridad) competitiva a largo plazo con sólo implementar tales sistemas innovadores. Ello se debe en parte a la incesante e impredecible (y a veces predecible) evolución de las estructuras de mercado, de las demandas y de la tecnología de productos y de procesos. Por tanto, puede ser arriesgado el hacer predicciones de posibles rendimientos del impacto de futuros RMSs, desde mucha de la literatura teórica y empírica relacionada con el tema. Además, la evidencia de estudios empíricos en HPM muestra que la piedra angular de la competitividad industrial no es crear una nueva tendencia, sino más bien mejorar continuamente al seleccionar y adaptar, según sea necesario, sólo las practicas avanzadas de producción (PAPs) que se ajusten al contexto especifico de la fábrica, estableciendo vínculos entre las PAPs existentes y las nuevas por instalar. Así pues, tomando el contexto del HPM, se establecen las condiciones actuales para la implementación del RMS. Finalmente, este artículo hace sugerencias en relación alRMSe identifica posibles direcciones para futura investigación.
PRÉSENTATION
Authors: Bouffard Léandre , Lapierre Sylvie 
Published: June 2017

Cette introduction a pour objectif de présenter les contributions au présent dossier sur le bonheur. Auparavant, nous abordons quelques points qui nous semblent comporter un intérêt certain : les « bénéfices » du bonheur, sa contagion, la réticence qu’il suscite, les ingrédients du bonheur que constituent le contact avec la nature et les beaux-arts, enfin, la génétique et l’épigénétique du bonheur.
Using high-throughput sequencing of ITS2 to describe Symbiodinium metacommunities in St. John, US Virgin Islands
Authors: Cunning Ross , Gates Ruth D. , Edmunds Peter J. 
Published: June 2017

Symbiotic microalgae (Symbiodinium spp.) strongly influence the performance and stress-tolerance of their coral hosts, making the analysis of Symbiodinium communities in corals (and metacommunities on reefs) advantageous for many aspects of coral reef research. High-throughput sequencing of ITS2 nrDNA offers unprecedented scale in describing these communities, yet high intragenomic variability at this locus complicates the resolution of biologically meaningful diversity. Here, we demonstrate that generating operational taxonomic units by clustering ITS2 sequences at 97% similarity within, but not across, samples collapses sequence diversity that is more likely to be intragenomic, while preserving diversity that is more likely interspecific. We utilize this ‘within-sample clustering’ to analyze Symbiodinium from ten host taxa on shallow reefs on the north and south shores of St. John, US Virgin Islands. While Symbiodinium communities did not differ between shores, metacommunity network analysis of host-symbiont associations revealed Symbiodinium lineages occupying ‘dominant’ and ‘background’ niches, and coral hosts that are more ‘flexible’ or ‘specific’ in their associations with Symbiodinium. These methods shed new light on important questions in coral symbiosis ecology, and demonstrate how application-specific bioinformatic pipelines can improve the analysis of metabarcoding data in microbial metacommunity studies.
Temporal Information Partitioning Networks (TIPNets): A process network approach to infer ecohydrologic shifts
Authors: Goodwell Allison E. , Kumar Praveen 
Published: June 2017

AbstractIn an ecohydrologic system, components of atmospheric, vegetation, and root‐soil subsystems participate in forcing and feedback interactions at varying time scales and intensities. The structure of this network of complex interactions varies in terms of connectivity, strength, and time scale due to perturbations or changing conditions such as rainfall, drought, or land use. However, characterization of these interactions is difficult due to multivariate and weak dependencies in the presence of noise, nonlinearities, and limited data. We introduce a framework for Temporal Information Partitioning Networks (TIPNets), in which time‐series variables are viewed as nodes, and lagged multivariate mutual information measures are links. These links are partitioned into synergistic, unique, and redundant information components, where synergy is information provided only jointly, unique information is only provided by a single source, and redundancy is overlapping information. We construct TIPNets from 1 min weather station data over several hour time windows. From a comparison of dry, wet, and rainy conditions, we find that information strengths increase when solar radiation and surface moisture are present, and surface moisture and wind variability are redundant and synergistic influences, respectively. Over a growing season, network trends reveal patterns that vary with vegetation and rainfall patterns. The framework presented here enables us to interpret process connectivity in a multivariate context, which can lead to better inference of behavioral shifts due to perturbations in ecohydrologic systems. This work contributes to more holistic characterizations of system behavior, and can benefit a wide variety of studies of complex systems.
Modeling solar energetic particle events using ENLIL heliosphere simulations
Authors: Luhmann J. G. , Mays M. L. , Odstrcil D. , Li Yan , Bain H. , Lee C. O. , Galvin A. B. , Mewaldt R. A. , Cohen C. M. S. , Leske R. A. , Larson D. , Futaana Y. 
Published: June 2017

AbstractSolar energetic particle (SEP) event modeling has gained renewed attention in part because of the availability of a decade of multipoint measurements from STEREO and L1 spacecraft at 1 AU. These observations are coupled with improving simulations of the geometry and strength of heliospheric shocks obtained by using coronagraph images to send erupted material into realistic solar wind backgrounds. The STEREO and ACE measurements in particular have highlighted the sometimes surprisingly widespread nature of SEP events. It is thus an opportune time for testing SEP models, which typically focus on protons ~1–100 MeV, toward both physical insight to these observations and potentially useful space radiation environment forecasting tools. Some approaches emphasize the concept of particle acceleration and propagation from close to the Sun, while others emphasize the local field line connection to a traveling, evolving shock source. Among the latter is the previously introduced SEPMOD treatment, based on the widely accessible and well‐exercised WSA‐ENLIL‐cone model. SEPMOD produces SEP proton time profiles at any location within the ENLIL domain. Here we demonstrate a SEPMOD version that accommodates multiple, concurrent shock sources occurring over periods of several weeks. The results illustrate the importance of considering longer‐duration time periods and multiple CME contributions in analyzing, modeling, and forecasting SEP events.
Reply to comment by Fred L. Ogden et al. on “Beyond the SCS‐CN method: A theoretical framework for spatially lumped rainfall‐runoff response”
Authors: Bartlett M. S. , Parolari A. J. , McDonnell J. J. , Porporato A. 
Published: June 2017

AbstractThough Ogden et al. list several shortcomings of the original SCS‐CN method, fit for purpose is a key consideration in hydrological modelling, as shown by the adoption of SCS‐CN method in many design standards. The theoretical framework of Bartlett et al. [2016a] reveals a family of semidistributed models, of which the SCS‐CN method is just one member. Other members include event‐based versions of the Variable Infiltration Capacity (VIC) model and TOPMODEL. This general model allows us to move beyond the limitations of the original SCS‐CN method under different rainfall‐runoff mechanisms and distributions for soil and rainfall variability. Future research should link this general model approach to different hydrogeographic settings, in line with the call for action proposed by Ogden et al.
Fault estimation of wind turbines using combined adaptive and parameter estimation schemes
Authors: Witczak Marcin , Rotondo Damiano , Puig Vicenç , Nejjari Fatiha , Pazera Marcin 
Published: June 2017

SummaryThis paper addresses the problem of fault estimation in wind turbines using a joint fault and state estimation scheme. The scheme assumes a set of possible faults affecting the dynamics of the wind turbine. Then, a combined adaptive and parameter estimation scheme is developed taking into consideration that process disturbances and sensor noises are unknown but bounded in an ellipsoid. Two subcases are considered depending on the satisfaction of a certain rank condition. The proposed approach is applied to a wind turbine based on a benchmark system model. The benchmark represents relevant fault scenarios, including sensor, actuator, and process faults. The proposed approach focuses on the last group of faults. Finally, the obtained results show that a satisfactory fault estimation is achieved against a set of predefined fault scenarios.
Multicompartment Drug Release System for Dynamic Modulation of Tissue Responses
Authors: Morris Aaron H. , Mahal Rajwant S. , Udell Jillian , Wu Michelle , Kyriakides Themis R. 
Published: June 2017

AbstractPharmacological modulation of responses to injury is complicated by the need to deliver multiple drugs with spatiotemporal resolution. Here, a novel controlled delivery system containing three separate compartments with each releasing its contents over different timescales is fabricated. Core–shell electrospun fibers create two of the compartments in the system, while electrosprayed spheres create the third. Utility is demonstrated by targeting the foreign body response to implants because it is a dynamic process resulting in implant failure. Sequential delivery of a drug targeting nuclear factor‐κB (NF‐κB) and an antifibrotic is characterized in in vitro experiments. Specifically, macrophage fusion and p65 nuclear translocation in the presence of releasate or with macrophages cultured on the surfaces of the constructs are evaluated. In addition, releasate from pirfenidone scaffolds is shown to reduce transforming growth factor‐β (TGF‐β)‐induced pSMAD3 nuclear localization in fibroblasts. In vivo, drug eluting constructs successfully mitigate macrophage fusion at one week and fibrotic encapsulation in a dose‐dependent manner at four weeks, demonstrating effective release of both drugs over different timescales. Future studies can employ this system to improve and prolong implant lifetimes, or load it with other drugs to modulate other dynamic processes.
The Viologen Cation Radical Pimer: A Case of Dispersion‐Driven Bonding
Authors: Geraskina Margarita R. , Dutton Andrew S. , Juetten Mark J. , Wood Samuel A. , Winter Arthur H. 
Published: June 2017

AbstractThe π bonds between organic radicals have generated excitement as an orthogonal interaction for designing self‐assembling architectures in water. A systematic investigation of the effect of the viologen cation radical structure on the strength and nature of the pimer bond is provided. A striking and unexpected feature of this π bond is that the bond strength is unchanged by substitution with electron‐donating groups or withdrawing groups or with increased conjugation. Furthermore, the interaction is undiminished by sterically bulky N‐alkyl groups. Theoretical modeling indicates that strong dispersion forces dominate the interaction between the radicals, rationalizing the insensitivity of the bonding interaction to substituents: The stacking of polarizable π radicals leads to attractive dispersion forces in excess of typical dispersion interactions of small molecules and helps overcome the Coulombic repulsion of bringing two cationic species into contact.
Segmental, Domain‐Selective Perdeuteration and Small‐Angle Neutron Scattering for Structural Analysis of Multi‐Domain Proteins
Authors: Sonntag Miriam , Jagtap Pravin Kumar Ankush , Simon Bernd , Appavou Marie‐Sousai , Geerlof Arie , Stehle Ralf , Gabel Frank , Hennig Janosch , Sattler Michael 
Published: June 2017

AbstractMulti‐domain proteins play critical roles in fine‐tuning essential processes in cellular signaling and gene regulation. Typically, multiple globular domains that are connected by flexible linkers undergo dynamic rearrangements upon binding to protein, DNA or RNA ligands. RNA binding proteins (RBPs) represent an important class of multi‐domain proteins, which regulate gene expression by recognizing linear or structured RNA sequence motifs. Here, we employ segmental perdeuteration of the three RNA recognition motif (RRM) domains in the RBP TIA‐1 using Sortase A mediated protein ligation. We show that domain‐selective perdeuteration combined with contrast‐matched small‐angle neutron scattering (SANS), SAXS and computational modeling provides valuable information to precisely define relative domain arrangements. The approach is generally applicable to study conformational arrangements of individual domains in multi‐domain proteins and changes induced by ligand binding.
Controlling Reaction Selectivity through the Surface Termination of Perovskite Catalysts
Authors: Polo‐Garzon Felipe , Yang Shi‐Ze , Fung Victor , Foo Guo Shiou , Bickel Elizabeth E. , Chisholm Matthew F. , Jiang De‐en , Wu Zili 
Published: June 2017

AbstractAlthough perovskites have been widely used in catalysis, tuning of their surface termination to control reaction selectivity has not been well established. In this study, we employed multiple surface‐sensitive techniques to characterize the surface termination (one aspect of surface reconstruction) of SrTiO3 (STO) after thermal pretreatment (Sr enrichment) and chemical etching (Ti enrichment). We show, by using the conversion of 2‐propanol as a probe reaction, that the surface termination of STO can be controlled to greatly tune catalytic acid/base properties and consequently the reaction selectivity over a wide range, which is not possible with single‐metal oxides, either SrO or TiO2. Density functional theory (DFT) calculations explain well the selectivity tuning and reaction mechanism on STO with different surface termination. Similar catalytic tunability was also observed on BaZrO3, thus highlighting the generality of the findings of this study.
Visible‐Light‐Driven Aza‐ortho‐quinone Methide Generation for the Synthesis of Indoles in a Multicomponent Reaction
Authors: Liu Yi‐Yin , Yu Xiao‐Ye , Chen Jia‐Rong , Qiao Ming‐Ming , Qi Xiaotian , Shi De‐Qing , Xiao Wen‐Jing 
Published: June 2017

AbstractA visible‐light‐driven radical‐mediated strategy for the in situ generation of aza‐ortho‐quinone methides from 2‐vinyl‐substituted anilines and alkyl radical precursors is described. This process enables an efficient multicomponent reaction of 2‐vinylanilines, halides, and sulfur ylides, and has a wide substrate scope and good functional group tolerance. Treatment of the cycloaddition products with a base leads to densely functionalized indoles in a single‐flask operation.