bluuebunny/crossref_metadata_2025_split huggingface dataset:
Illegal Detectorism and Archaeological Heritage: Criminal and Administrative Punitive Systems in Spain
Authors: Yáñez Ana 
Published: January 2017

AbstractThis paper details the punitive responses that Spain’s legal system has established for attacks
on archaeological goods through the use of metal detectors. These responses to illegal acts are not the
same across the board; sometimes they stem from the criminal justice system (in the most serious cases)
and sometimes from the Public Authorities. Below, I have analysed these responses and their scope in
an aim to provide a broad view of the different instruments related to the fight against archaeological
looting.
Influence of expanded graphite coming from the electrochemical oxidation of phenol on cement-polymer matrix
Authors: Ślosarczyk Agnieszka , Krawczyk Piotr 
Published: January 2017

Abstract
In presented article the polymer-modified cement mortars with expanded graphite covered by the oligomer film, being a by-product of phenol electro-oxidation, were investigated. The changes in the morphology of EG and EG/oligomer as well as in the microstructure of cement-polymer composites modified with EG/oligomer were verified using the scanning electron microscopy (SEM). The evaluation of adhesion between EG/oligomer and cement-polymer mortar based on the mechanical tests, especially their flexural behavior. It was shown that the oligomer film formed on EG surface made graphite flakes more durable and resistant to bending. Moreover, the oligomer due to the interaction with polymer network in cement-polymer mortar led to the improvement of flexural toughness of composite.
Content of PAHs, activities of γ-radionuclides and ecotoxicological assessment in biochars
Authors: Gondek Krzysztof , Mierzwa-Hersztek Monika , Smreczak Bożena , Baran Agnieszka , Kopeć Michał , Mróz Tomasz , Janowski Paweł , Bajda Tomasz , Tomczyk Anna 
Published: January 2017

Abstract
The aim of this research was to determine the effect of thermal conversion temperature and plant material addition to sewage sludge on the PAHs content and the activity of selected γ-radionuclides in biochars, and to conduct an ecotoxicological assessment. The pyrolysis of the mixtures of sewage sludge and plant materials at 300°C and such temperature caused an increase in the contents of 2- and 3-ring hydrocarbons. During the pyrolysis of organic materials at 600°C, the amount of the following compounds was reduced in biochars: benzo[b]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, indeno[1,2,3c,d]pyrene, dibenzo[a,h]anthracene, and benzo[g,h,i]perylene. Among γ-radioisotopes of the elements, natural radiogenic isotopes were dominant. 137Cs was the only artificial radioactive isotope. The pyrolysis of the mixtures of municipal sewage sludge and plant materials revealed that isotope 40K had the highest radioactive activity. In the case of other analysed nuclides, activities of 212Pb, 214Pb, 214Bi, and 137Cs were determined after the sample pyrolysis. The extracts from the mixtures of sewage sludge and plant materials were non-toxic to Vibrio fischeri.
Model development of integrated CPOx reformer and SOFC stack system
Authors: Pianko-Oprych Paulina , Hosseini Seyed Mehdi , Jaworski Zdzislaw 
Published: January 2017

Abstract
The main purpose of this study was to develop a mathematical model, in a steady state and dynamic mode, of a Catalytic Partial Oxidation (CPOx) reformer – Solid Oxide Fuel Cell (SOFC) stack integrated system in order to assess the system performance. Mass balance equations were written for each component in the system together with energy equation and implemented into the MATLAB Simulink simulation tool. Temperature, gas concentrations, pressure and current density were computed in the steady-state mode and validated against experimental data. The calculated I–V curve matched well the experimental one. In the dynamic modelling, several different conditions including step changes in fuel flow rates, stack voltage as well as temperature values were applied to estimate the system response against the load variations. Results provide valuable insight into the operating conditions that have to be achieved to ensure efficient CPOx performance for fuel processing for the SOFC stack applications.
Water-borne pressure-sensitive adhesives acrylics modified using amorphous silica nanoparticles
Authors: Czech Zbigniew , Maciejewski Zbigniew , Kondratowicz-Maciejewska Krystyna 
Published: January 2017

AbstractThe application of water-borne pressure-sensitive adhesives (PSA) based on acrylics is increasing in a variety of industrial areas. The have been used for manufacturing of double sided and carrier free mounting tapes, splicing tapes, marking and sign films, self-adhesive labels, packaging tapes, protective films and diverse high quality medical materials. Nano-sized inorganic fillers can modify diverse adhesive and self-adhesive coating properties such as tack, peel adhesion, shear strength at 20°C and 70°C, and removability Amorphous synthetic silica nanoparticles in form of water dispersions: Ludox PX-30 (30 wt.% silica stabilizing with counter ion sodium), Ludox PT-40 (40 wt.% silica stabilizing with counter ion sodium), Ludox PT-40AS (40 wt.% silica stabilizing with counter ion ammonium), and Ludox PW-50 (50 wt.% silica stabilizing with counter ion sodium) (from Grace) in concentrations between 1 and 5wt.% were used for modifying of water-born pressure-sensitive adhesive acrylics: Acronal 052, Acronal CR 516 (both BASF) and Plextol D273 (Synthomer) properties. It has been found in this study that the nano-technologically reinforced system containing of Acronal 052 and amorphous silica Ludox PX-30 showed a great enhancement in tack, peel adhesion and shear strength. In this paper we evaluate the performance of Acronal 052 modified with amorphous silica Ludox PX-30.
Serum level of apelin-13 negatively correlated with NT-proBNP in heart failure patients
Authors: Goidescu Cerasela Mihaela , Anton Florin Petru , Leucuța Daniel Corneliu , Mircea Petru Adrian , Vida-Simiti Luminița Animarie 
Published: January 2017

Abstract

Background: Apelin is a potent endogenous inotropic peptide with a major role in counteracting the aldosterone and angiotensin II and their negative effects on the cardiovascular system. The exact role of apelin in the patho-physiology of this disease is not well understood. We aimed to investigate the possible associations of apelin-13 with clinical and paraclinical characteristics in HF patients as well as studying its dynamics during the course of the heart failure.

Method: We performed a prospective observational cohort single-center study. We compared the baseline serum levels of apelin-13 and NT-proBNP level in 53 heart failure patients (acute heart failure, chronic compensated heart failure and chronic decompensated heart failure). We divided the patients according to the apelin-13 level: above and below the median, and we analyzed the relationship between serum apelin-13 and the clinical, echocardiographic, electrocardiographic and biological parameters. Twenty patients were followed-up (after an average time interval of 9 months), investigating the same parameters.

Results: The median of apelin-13 was 495pg/mL (IQR 276-845pg/mL). We found strong, negative correlation between the serum levels of apelin-13 and NT-proBNP (Spearman rho= −0.83, p<0.001). For the reassessed patients the median apelin level was significantly higher at follow-up (460 pg/mL, IQR 342-871 pg/mL) as compared with the baseline level (395 pg/mL, IQR 270-603 pg/mL), p=0.019, and maintained the negative correlation with NT-proBNP level (Spearman’s rho −0.7, p<0.001. The Low Apelin-13 group have higher NT-proBNP levels and also contains all the patients in NYHA IV class heart failure, 71% of the acute HF patients, and 7 of 8 patients who died before follow-up.

Conclusion: Apelin-13 was negatively correlated with NT-proBNP. The Low Apelin-13 group contained the majority of the patients with a negative outcome (death before follow-up), most of the patients who presented with acute HF and all the patients in NYHA IV class.
Genetic polymorphisms of glutathione S transferase and cervical intraepithelial neoplasia
Authors: Daniel Mureșan , Cătană Andreea , Popp Radu Anghel , Dumitraș Diana Elena , Stamatian Florin , Buzoianu Anca Dana , Rotar Ioana Cristina 
Published: January 2017

Abstract

Aim: The present study aim to analyze the relationship between GST M/T genotypes of glutathione S-transferases and cervical intraepithelial neoplasia.

Materials and Methods: A prospective case-control study has been designed including 69 cases with different degrees of cervical dysplasia and 107 controls. All patients had been examined colposcopically. For every patient both cervical and blood specimen have been obtained. The peripheral blood was used for GST M/T genotyping. The statistical analysis was performed using OR and chi-square at a level of significance inferior to 0.05.

Results: No statistically significant differences had been found between cases and controls for GST T-/M- geno-type (T-/M-, χ2=0.03, p= 0.8610) and T+/M+ χ2=0.65, p = 0.4197. Patients with in situ carcinoma had significant GST genotype association for T-/M+ genotype (OR=4.66, CI 95% [0.6528,24.9725], χ2=4.6, p=0.0314) and for T+/M- genotype (OR=0.12, CI 95% [0.0027,0.9465], χ2=0.05, p=0.0219).

Conclusion: The combination of GST genotypes can be included in a predictive score for patients with cervical carcinoma.
Inhibitory effects on the HMG-CoA Reductase in the chemical constituents of the Cassia mimosoides Linn
Authors: Shen Chuangpeng , Huang Liping , Xiang Hua , Deng Minzhen , Gao Huahong , Zhu Zhangzhi , Liu Min , Luo Guangbo 
Published: January 2017

Abstract
Cassia mimosoides Linn has been used from ancient times and used for treating hepatitis for its supposedly medically beneficial properties. In this study, different constituents of the Cassia mimosoides Linn (β-Sitosterol, Oleanolic Acid, Emodin, Carotene, Resorcinol, Luteolin, and α-L-Rhamnose) were evaluated for potential anti-HMG-CoA reductase effect. The inhibitory effects of HMG-CoA reductase of Cassia mimosoides Linn extracts and Pravastatin inhibitor at different concentrations (at doses of 1, 5, 25 or 125 μg/mL, respectively) in reaction system (70 mmol/L phosphate buffer, 200mmol/L NADPH, 5 μg HMG-CoA reductase, 2 mmol/L EDTA, 2 mmol/L cysteamine, 0.06% BSA) into 37°C preheat HMG-CoA for initiating this reaction, and then determined the change of HMG-CoA reductase activity (ΔAΔt) at 340 nm, the inhibition ratio of HMG-CoA reductase activity and its dynamic change of inhibitory effect within 15 min and the descent rate of NADPH. Emodin, Luteolin, β-Sitosterol, Oleanolic Acid, α-L-Rhamnose and Carotene showed good inhibition of HMG-CoA reductase activity. Among them, only the Emodin (1 and 5 μg/mL) groups showed a significant decrease of HMG-CoA reductase activity compared to the Pravastatin (1 and 5 μg/mL) groups respectively. In addition, the HMG-CoA reductase activity in the Emodin and Luteolin (25 and 125 μg/mL) groups was clearly lower than the Pravastatin (25 and 125 μg/mL) groups respectively. And the Emodin and Luteolin (1, 5, 25 or 125 μg/mL) groups exhibited a stable effect on inhibiting the HMG-CoA reductase within 15 min. These findings further support the exploration of Cassia mimosoides Linn as a potential agent for the treatment of hepatitis in future studies.
Influence of Selected Factors on the Sawing Capacity of Sawmills in the Czech Republic
Authors: Bomba J. , Böhm M. , Šedivka P. , Friess F. , Orálková R. 
Published: January 2017

Abstract
The paper deals with the influence of selected factors on the sawing capacity of small and medium-sized sawmills with a sawing capacity to 99 999 m3/year under the conditions of the Czech Republic. One of the objectives was to analyze the current state of production technology and machinery. In total, data was analyzed from 195 sawmills that were divided into five groups according to the volume of processed timber. A production function was created from the ascertained results in order to determine the sawing capacity for small and medium-sized sawmills. It was found out that sawing capacity is mostly affected by the number of employees. The influence of the degree of mechanization and the main sawing technology was evaluated, too.
Biodiversity Evaluation of Geotrichum candidum Link. Is Arthrosporic Nucleus Number in Geotrichum candidum related to the Fungus Biodiversity?
Authors: Koňuchová M. , Lehotová V. , Šípková A. , Piecková E. , Valík Ľ. 
Published: January 2017

Abstract

Geotrichum candidum species exhibits properties of both moulds and yeasts and its affiliation to one of the groups has been intensively discussed. It is because this filamentous microscopic fungus is displaying substantial morphological variability and wide phenotypic diversity. The present study assesses the variability of arthrosporic nucleus number of twelve isolates of G. candidum originating from artisanal manufacturing and ripened traditional Slovak cheeses. Results showed that arthrospores of the studied isolates contained on average 1.5 ± 0.7 (on the Gorodkova medium) and 1.5 ± 0.6 (on the McClary medium) Hoechst 33258-stained nuclei (range 1–4 nuclei on both agars) after a 7-day cultivation at 25°C. Majority of arthrospores comprised one nucleus, irrespective to the used nutrient-limited medium. Generally, a higher relative nucleus number per arthrospore was exhibited in yeast-like isolates with microscopic structure composed predominantly of spores, while it was lower in vegetative hyphae. These isolates originated from ewe’s lump cheese. Our study reveals that the arthrosporic nucleus number of the G. candidum strains is closely related to morphotype and origin of this yeast.
Verbs of Command and the Status of Their Embedded Complements in Chinese
Authors: Colum Yip Chak-Lam 
Published: January 2017

Abstract
This paper argues against Yue’s (1999) view that complements to verbs of commands (jiao ‘to ask/to tell,’ qing ‘to request,’ quan ‘to persuade,’ etc.) are embedded imperatives with a covert [+second person] subject pronoun. Evidence against the embedded imperative analysis include the presence of partial control, the absence of blocking effect in long-distance binding, the incompatibility between these complement clauses and the polite imperative marker qing, and the fact that Yue’s proposed covert [+second person] pronoun cannot be made overt. Since verbs of commands participate in object control, the present proposal agrees with Zhu’s (1982) treatment of verbs of command as pivotal verbs. Finally, complement clauses of verbs of command are not embedded imperatives as bie can also appear with third person subjects, which shows that the negator does not mark imperative but irrealis and deontic modality. Hence, its presence in complements of verbs of command does not lead to an embedded imperative analysis.
Comparing Methods for Computing the Time of Concentration in a Medium-Sized Hungarian Catchment
Authors: Nagy E. D. , Torma P. , Bene K. 
Published: January 2017

Abstract
One of the most often-used parameters that describes morphology and runoff from a watershed is the time of concentration (Tc). At gauged watersheds, Tc can be determined using rainfall and a runoff hydrograph, while for ungauged watersheds, empirical equations are used. A good initial estimate of Tc greatly improves the accuracy of runoff predictions. In our study, we applied 14 empirical equations to determine Tc. Tarján Creek, which is located in northeastern Hungary, was selected as the trial gauged watershed. It is located in a mountainous region with an area of 72 km2. The input parameters for the empirical equations were determined using geoinformatical tools. To evaluate the accuracy of the empirical equations, HEC-HMS was used to model the runoff. Using the measured runoff data, both continuous and event-based models were calibrated. For direct runoff, Clark’s unit hydrograph was selected. Tc is one of the input parameters for this model. After the calibration, the estimates from the empirical equations for Tc were compared to the HEC-HMS calibrated values for each subwatershed. The empirical estimates varied greatly. The Wisnovszky-equation, which is most often used in Hungary, underestimated Tc.
Utilization of Historical Maps in the Land Use Change Impact Studies: A Case Study from Myjava River Basin
Authors: Valent P. , Rončák P. , Maliariková M. , Behan Š. 
Published: January 2017

Abstract
The way land is used has a significant impact on many hydrological processes that determine the generation of flood runoff or soil erosion. Advancements in remote sensing which took place in the second half of the 20th century have led to the rise of a new research area focused on analyses of land use changes and their impact on hydrological processes. This study deals with an analysis of the changes in land use over a period of almost three centuries in the Myjava River catchment, which has an outlet at Šaštín-Stráže. In order to obtain information about the way the land was used in the past, three historical mappings representing various periods were used: the first (1st) military mapping (1764-1787), second (2nd) military mapping (1807-1869), and a military topographic mapping (1953-1957). The historical mappings have been manually vectorised in an ArcGIS environment to identify various land use categories. The historical evolution of land use was further compared with a concurrent land use mapping, which was undertaken in 2010 and exploited remote sensing techniques. The study also quantifies the impact of these changes on the long-term catchment runoff as well as their impact on flows induced by extreme precipitation events. This analysis was performed using the WetSpa distributed hydrological model, which enables the simulation of catchment runoff in a daily time step. The analysis showed that the selected catchment has undergone significant changes in land use, mainly characterized by massive deforestation at the end of the 18th century and land consolidation in the middle of the 20th century induced by communist collectivisation. The hydrological simulations demonstrated that the highest and lowest mean annual runoffs were simulated in the first (1st military mapping) and the last (concurrent land use monitoring) time intervals respectively with the smallest and largest percentages of forested areas.
Evaluation of Macroinvertebrate Data Based on Autoecological Information
Authors: Juhász I. 
Published: January 2017

Abstract
Various data (biological, chemical, hydrological and morphological) have been gathered within the frame of the monitoring of the Water Framework Directive from 2007 in Hungary. This data only used a status assessment of certain water bodies in Hungary. The macroinvertebrates indicate many environmental factors well; therefore, they are very useful in detecting changes in the status of an environment. The main aim in this research was to investigate changes in environmental variables and decide how these variables cause big changes in the macroinvertebrate fauna. The macroinvertebrate data was processed using the ASTERICS 4.0.4 program. The program calculated some important metrics (i.e., microhabitat distributions, longitudinal zonation, functional feeding guilds, etc.). These metrics were compared with the chemical and hydrological data. The main conclusion is that if we have enough of a frequency and quality of macroinvertebrate data, we can understand changes in the environment of an ecosystem.
Subgenic Pol II interactomes identify region‐specific transcription elongation regulators
Authors: Harlen Kevin M , Churchman L Stirling 
Published: January 2017

AbstractTranscription, RNA processing, and chromatin‐related factors all interact with RNA polymerase II (Pol II) to ensure proper timing and coordination of transcription and co‐transcriptional processes. Many transcription elongation regulators must function simultaneously to coordinate these processes, yet few strategies exist to explore the complement of factors regulating specific stages of transcription. To this end, we developed a strategy to purify Pol II elongation complexes from subgenic regions of a single gene, namely the 5′ and 3′ regions, using sequences in the nascent RNA. Applying this strategy to Saccharomyces cerevisiae, we determined the specific set of factors that interact with Pol II at precise stages during transcription. We identify many known region‐specific factors as well as determine unappreciated associations of regulatory factors during early and late stages of transcription. These data reveal a role for the transcription termination factor, Rai1, in regulating the early stages of transcription genome‐wide and support the role of Bye1 as a negative regulator of early elongation. We also demonstrate a role for the ubiquitin ligase, Bre1, in regulating Pol II dynamics during the latter stages of transcription. These data and our approach to analyze subgenic transcription elongation complexes will shed new light on the myriad factors that regulate the different stages of transcription and coordinate co‐transcriptional processes.
A Robust and Powerful Set-Valued Approach to Rare Variant Association Analyses of Secondary Traits in Case-Control Sequencing Studies
Authors: Kang Guolian , Bi Wenjian , Zhang Hang , Pounds Stanley , Cheng Cheng , Shete Sanjay , Zou Fei , Zhao Yanlong , Zhang Ji-Feng , Yue Weihua 
Published: January 2017

Abstract
In many case-control designs of genome-wide association (GWAS) or next generation sequencing (NGS) studies, extensive data on secondary traits that may correlate and share the common genetic variants with the primary disease are available. Investigating these secondary traits can provide critical insights into the disease etiology or pathology, and enhance the GWAS or NGS results. Methods based on logistic regression (LG) were developed for this purpose. However, for the identification of rare variants (RVs), certain inadequacies in the LG models and algorithmic instability can cause severely inflated type I error, and significant loss of power, when the two traits are correlated and the RV is associated with the disease, especially at stringent significance levels. To address this issue, we propose a novel set-valued (SV) method that models a binary trait by dichotomization of an underlying continuous variable, and incorporate this into the genetic association model as a critical component. Extensive simulations and an analysis of seven secondary traits in a GWAS of benign ethnic neutropenia show that the SV method consistently controls type I error well at stringent significance levels, has larger power than the LG-based methods, and is robust in performance to effect pattern of the genetic variant (risk or protective), rare or common variants, rare or common diseases, and trait distributions. Because of the SV method’s striking and profound advantage, we strongly recommend the SV method be employed instead of the LG-based methods for secondary traits analyses in case-control sequencing studies.