bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factor de penalidad de tags RFID instalados en vidrios de vehículos
Authors: Pineda Edwin , Neira Ernesto , Pantoja John J. , Vega Félix , Pedraza César 
Published: March 2017

Este documento presenta un estudio sobre la identificación de los principales parámetros que intervienen en el factor de penalidad para Tags RFID cuando son instalados sobre el vidrio frontal de los vehículos. Evaluamos las cuatro variables con importancia relevante sobre este factor de penalidad: Tipo de vidrio, película polarizada, la polarización de la onda electromagnética, y el tipo de tag. La evaluación se realiza mediante pruebas experimentales basadas en la técnica de Diseño Experimental. A partir de los resultados, se logra obtener un modelo simplificado para determinar el factor de penalidad de acuerdo a las variables analizadas.
Estandarización del modelo de negocios para el modelado estándar de datos
Authors: Reyna Monteverde Tino Eduardo 
Published: March 2017

Este artículo presenta un nuevo enfoque para determinar El Modelo Funcional de Negocio que se requiere para el modelo de datos del futuro sistema automatizado. El alcance de este nuevo esquema cubre la típica actividad empresarial que requiere de sistemas de información para la toma de decisiones empresariales. Se analizan los patrones de las áreas funcionales de toda empresa, llegando a presentar los esquemas estándar para cada una de ellas. Estos patrones son demostrados y sustentados debidamente. Los Sistemas Informáticos durante su vida útil sufren una serie de ajustes vía mantenimiento. Estos cambios generan muchos costos en tiempo y dinero. La estratégia para evitar esta situación es tomar como base un modelo de negocio estándar, el cual pueda ser personalizado vía parâmetros de acuerdo a los requerimentos particulares del usuario. Con el objetivo de encontrar el Modelo estándar de negocio se demuestra que son cuatro las Macro funciones básicas que de manera universal deben estar presentes en toda área de Negocios. Estas macro funciones son presentadas y detalladas. Para llegar a este esquema se demuestra que el servicio entregado por todas las áreas que forman la empresa son Productos tipo Servicio y por lo tanto deben cumplir de manera holística con el Ciclo de Vida de Producto (cuatro etapas del Ciclo). Los modelos se presentan tanto de manera gráfica como analítica. En base a este modelo de negocio estándar, se determinarán los requerimientos de información, imprescindibles para la etapa de análisis de los Sistemas de Información.
Association of CKD with Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation
Authors: Lüders Florian , Kaier Klaus , Kaleschke Gerrit , Gebauer Katrin , Meyborg Matthias , Malyar Nasser M. , Freisinger Eva , Baumgartner Helmut , Reinecke Holger , Reinöhl Jochen 
Published: March 2017

Background and objectives
Despitethe multiple depicted associations of CKD with reduced cardiovascular and overall prognoses, the association of CKD with outcome of patients undergoing transcatheter aortic valve implantation has still not been well described.

Design, setting, participants, & measurements
Data from all hospitalized patients who underwent transcatheter aortic valve implantation procedures between January 1, 2010 and December 31, 2013 in Germany were evaluated regarding influence of CKD, even in the earlier stages, on morbidity, in-hospital outcomes, and costs.

Results
A total of 28,716 patients were treated with transcatheter aortic valve implantation. A total of 11,189 (39.0%) suffered from CKD. Patients with CKD were predominantly women; had higher rates of comorbidities, such as coronary artery disease, heart failure at New York Heart Association 3/4, peripheral artery disease, and diabetes; and had a 1.3-fold higher estimated logistic European System for Cardiac Operative Risk Evaluation value. In-hospital mortality was independently associated with CKD stage ≥3 (up to odds ratio, 1.71; 95% confidence interval, 1.35 to 2.17; P<0.05), bleeding was independently associated with CKD stage ≥4 (up to odds ratio, 1.82; 95% confidence interval, 1.47 to 2.24; P<0.001), and AKI was independently associated with CKD stages 3 (odds ratio, 1.83; 95% confidence interval, 1.62 to 2.06) and 4 (odds ratio, 2.33; 95% confidence interval, 1.92 to 2.83 both P<0.001). The stroke risk, in contrast, was lower for patients with CKD stages 4 (odds ratio, 0.23; 95% confidence interval, 0.16 to 0.33) and 5 (odds ratio, 0.24; 95% confidence interval, 0.15 to 0.39; both P<0.001). Lengths of hospital stay were, on average, 1.2-fold longer, whereas reimbursements were, on average, only 1.03-fold higher in patients who suffered from CKD.

Conclusions
This analysis illustrates for the first time on a nationwide basis the association of CKD with adverse outcomes in patients who underwent transcatheter aortic valve implantation. Thus, classification of CKD stages before transcatheter aortic valve implantation is important for appropriate risk stratification.
Toxicidade do extrato hidroalcoólico das folhas de Cissus sicyoides
Authors: Dias Gabriela Tafaela , Lima Caliandra Maria Bezerra Luna , Lira Andressa Brito , Ramalho Josue Amaral , Oliveira Kardilandia Mendes , Diniz Margareth Fátima Formiga Melo 
Published: March 2017

Cissus sicyoides L. (cipó-anil, insulina vegetal), pertence à família Vitacea, é muito empregada pela população para o tratamento de diabetes. O objetivo desta pesquisa foi realizar uma triagem fitoquímica do extrato hidroalcóolico das folhas de C. sicyoides para utilizá-lo como fonte primária na realização do ensaio toxicológico com Artemia salina L. Foram realizados testes fitoquímicos do extrato hidroalcoólico das folhas de C. sicyoides para pesquisa dos metabólitos secundários e foi avaliado a atividade toxicológica utilizando cistos de A. salina para quantificar a concentração letal média (CL50). O extrato apresentou esteróides, taninos, flavonóides e saponinas, compostos que já haviam sido encontrados em outros estudos dessa espécie. Apresentou alta toxicidade frente à A. salina, reportando Concentração Letal Média (CL50) de 930,7 g mL-1, servindo de parâmetro para a realização de estudos posteriores em modelos animais com a pretensão de alcançar mais resultados para um uso seguro da planta da C. sicyoides.
Coadministration of Canagliflozin and Phentermine for Weight Management in Overweight and Obese Individuals Without Diabetes: A Randomized Clinical Trial
Authors: Hollander Priscilla , Bays Harold E. , Rosenstock Julio , Frustaci Mary Ellen , Fung Albert , Vercruysse Frank , Erondu Ngozi 
Published: March 2017

OBJECTIVE
To assess the efficacy and safety of coadministration of canagliflozin (CANA) and phentermine (PHEN) compared with placebo (PBO) and CANA or PHEN monotherapies in individuals who were overweight and obese without type 2 diabetes.

RESEARCH DESIGN AND METHODS
This 26-week, phase 2a, randomized, double-blind, PBO-controlled, multicenter, parallel-group study enrolled individuals who were obese or overweight without type 2 diabetes (N = 335, aged 18–65 years, BMI ≥30 to &lt;50 kg/m2 or BMI ≥27 to &lt;50 kg/m2 with hypertension and/or dyslipidemia). Participants were randomized (1:1:1:1) to receive PBO, CANA 300 mg, PHEN 15 mg, or coadministration of CANA 300 mg and PHEN 15 mg (CANA/PHEN) orally once daily. The primary end point was percent change in body weight from baseline to week 26; key secondary end points were the proportion of participants achieving weight loss ≥5% and change from baseline in systolic blood pressure.

RESULTS
CANA/PHEN provided statistically superior weight loss from baseline versus PBO at week 26 (least squares mean difference –6.9% [95% CI –8.6 to –5.2]; P &lt; 0.001). CANA/PHEN also provided statistically superior achievement of weight loss ≥5% and reduction in systolic blood pressure compared with PBO. CANA/PHEN was generally well tolerated, with a safety and tolerability profile consistent with that of the individual components.

CONCLUSIONS
CANA/PHEN produced meaningful reductions in body weight and was generally well tolerated in individuals who were overweight or obese without type 2 diabetes. Further studies are warranted to evaluate potential use of this combination for long-term weight management.
Fotografias como estratégia metodológica: perscrutando formas de tratamento pronominais brasileiras, moçambicanas e angolanas
Authors: Balsalobre ￼ Sabrina Rodrigues Garcia 
Published: March 2017

<div class="page" title="Page 132"><div class="section"><div class="layoutArea"><div class="column"><p><span>Brasil, Moçambique e Angola compartilham da língua portuguesa. Entretanto, esse sistema linguístico é atualizado de modos particulares em função de cada um dos contextos nacionais e de suas idiossincrasias. Particularmente, essa situação é válida ao se observar os usos pronominais da língua portuguesa em suas variedades brasileira, angolana e moçambicana. Ao se considerar apenas situações de interlocução, o sistema dispõe de pronomes pessoais que contemplam recursos pragmáticos de cortesia, intimidade, polidez, distanciamento hierárquico etc. por meio de formas como </span><span>tu</span><span>, </span><span>você</span><span>, </span><span>o senhor/a senhora</span><span>, </span><span>vocês</span><span>, </span><span>os senhores/as senhoras</span><span>. Além dessas formas pronominais, ainda está disponível sistemicamente ao falante a ausência do pronome (ou forma zero), em que a marca pessoal é demonstrada pela desinência verbal. Para a realização dessa pesquisa comparativa entre as três variedades do português, algumas escolhas metodológicas foram decisivas. Em especial, fez-se imprescindível o resgate de uma metodologia utilizada por pesquisadores brasileiros nos anos 1980. Trata-se do emprego de fotografias como motivador para a realização das entrevistas com os informantes. A partir da seleção das imagens de perfis sociais, foi possível realizar as entrevistas com os informantes. A proposta feita aos entrevistados era que lhes seria indicada, para cada imagem, uma instrução específica contendo um pedido acerca de endereço, referência a uma pessoa, o preço de determinado produto etc. Tendo compreendido a instrução, o informante estabelecia um diálogo com a pessoa da fotografia – a maioria dos informantes compreendia prontamente a proposta da entrevista e produzia naturalmente diversas formas de tratamento. Em geral, há a possibilidade de se estabelecer algumas tendências no comportamento linguístico dos informantes de um mesmo país, corroborando com a assertiva de que o português brasileiro, o moçambicano e o angolano são variedades linguísticas autônomas. </span></p></div></div></div></div>
Paleografia versus Alfabetização. Reflexões sobre História Social da Cultura Escrita
Authors: Castillo Gómez Antonio , Sáez Carlos 
Published: March 2017

Tradução ao português do texto "<em>Paleografía versus Alfabetización. </em><em>Reflexiones sobre Historia Social de la Cultura Escrita</em>", originalmente em espanhol, elaborada por Leonardo Lennertz Marcotulio e Adriana Angelita da Conceição.
The Roles of Information Technology in Islamic Bank Knowledge Management: A study of Two Syariah Banks in Palu
Authors: Nurdin Nurdin 
Published: March 2017

Information technology has been considered as a vital tool for modern organizations to support their knowledge management projects. Previous studies have found that success knowledge management projects were supported by various information technology infrastructures. They addressed how information technology has succesfully implemented to support knowledge management project within conventional banks. However, limited study has been proposed regarding how information technology play roles in support knowledge management project within Islamic banks. Through the case study approach, the author studied the use of information technology for knowledge management process within two Bank Syariah (Bank Mandiri and Bank BNI Syariah) in Palu Central Sulawesi. The author collected data through observation, written material, and in-depth interviews with key informants from both banks. The findings show that information technology infrastructures have played important roles in support knowledge management projects within the Islamic banks. Those information technology infrastructures includes internet, intranet, websites, communication application such as email, and social media. This study sheds light and provides new insight on how information technology has succesfully used to support knowledge management within Islamic banks. The results benefits both academic and practioners in Islamic banks and knowledge managemet area. As the social media was an important finding for knowledge management in Islamic banks, future research need to focus on how social media should be used for knowledge management projects in Islamic banks
The impact of preoperative epidural injections on postoperative infection in lumbar fusion surgery
Authors: Singla Anuj , Yang Scott , Werner Brian C. , Cancienne Jourdan M. , Nourbakhsh Ali , Shimer Adam L. , Hassanzadeh Hamid , Shen Francis H. 
Published: March 2017

OBJECTIVELumbar epidural steroid injections (LESIs) are performed for both diagnostic and therapeutic purposes for a variety of indications, including low-back pain, the leading cause of disability and expense due to work-related conditions in the US. The steroid agent used in epidural injections is reported to relieve nerve root inflammation, local ischemia, and resultant pain, but the injection may also have an adverse impact on spinal surgery performed thereafter. In particular, the possibility that preoperative epidural injections may increase the risk of surgical site infection after lumbar spinal fusion has been reported but has not been studied in detail. The goal of the present study was to use a large national insurance database to analyze the association of preoperative LESIs with surgical site infection after lumbar spinal fusion.METHODSA nationwide insurance database of patient records was used for this retrospective analysis. Current Procedural Terminology codes were used to query the database for patients who had undergone LESI and 1- or 2-level lumbar posterior spinal fusion procedures. The rate of postoperative infection after 1- or 2-level posterior spinal fusion was analyzed. These study patients were then divided into 3 separate cohorts: 1) lumbar spinal fusion performed within 1 month after LESI, 2) fusion performed between 1 and 3 months after LESI, and 3) fusion performed between 3 and 6 months after LESI. The study patients were compared with a control cohort of patients who underwent lumbar fusion without previous LESI.RESULTSThe overall 3-month infection rate after lumbar spinal fusion procedure was 1.6% (1411 of 88,540 patients). The infection risk increased in patients who received LESI within 1 month (OR 2.6, p < 0.0001) or 1–3 months (OR 1.4, p = 0.0002) prior to surgery compared with controls. The infection risk was not significantly different from controls in patients who underwent lumbar fusion more than 3 months after LESI.CONCLUSIONSLumbar spinal fusion performed within 3 months after LESI may be associated with an increased rate of postoperative infection. This association was not found when lumbar fusion was performed more than 3 months after LESI.
Breast Cancer—Major changes in the American Joint Committee on Cancer eighth edition cancer staging manual
Authors: Giuliano Armando E. , Connolly James L. , Edge Stephen B. , Mittendorf Elizabeth A. , Rugo Hope S. , Solin Lawrence J. , Weaver Donald L. , Winchester David J. , Hortobagyi Gabriel N. 
Published: March 2017

AbstractAnswer questions and earn CME/CNEThe revision of the eighth edition of the primary tumor, lymph node, and metastasis (TNM) classification of the American Joint Commission of Cancer (AJCC) for breast cancer was determined by a multidisciplinary team of breast cancer experts. The panel recognized the need to incorporate biologic factors, such as tumor grade, proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression prognostic panels into the staging system. AJCC levels of evidence and guidelines for all tumor types were followed as much as possible. The panel felt that, to maintain worldwide value, the tumor staging system should remain based on TNM anatomic factors. However, the recognition of the prognostic influence of grade, hormone receptor expression, and HER2 amplification mandated their inclusion into the staging system. The value of commercially available, gene‐based assays was acknowledged and prognostic input added. Tumor biomarkers and low Oncotype DX recurrence scores can alter prognosis and stage. These updates are expected to provide additional precision and flexibility to the staging system and were based on the extent of published information and analysis of large, as yet unpublished databases. The eighth edition of the AJCC TNM staging system, thus, provides a flexible platform for prognostic classification based on traditional anatomic factors, which can be modified and enhanced using patient biomarkers and multifactorial prognostic panel data. The eighth edition remains the worldwide basis for breast cancer staging and will incorporate future online updates to remain timely and relevant. CA Cancer J Clin 2017;67:290–303. © 2017 American Cancer Society.
Trends in attractiveness of general practice as a career: surveys of views of UK-trained doctors
Authors: Lambert Trevor W , Smith Fay , Goldacre Michael J 
Published: March 2017

BackgroundIt is current UK policy to expand the numbers of newly qualified doctors entering training to become GPs, to meet increased demand.AimTo report on trends in young doctors’ views on the attractiveness of general practice as a career, compared with hospital practice.Design and settingQuestionnaire surveys in the UK.MethodSurveys of doctors, 3 years after graduation, conducted in successive year-of-qualification cohorts between 1999 and 2015.ResultsThe overall response rate from contactable doctors was 55%. In response to the statement‘General practice is more attractive than hospital practice for doctors at present’, 59% of doctors agreed in the 1999 survey, 77% in 2005, and only 36% in 2015. One-third of doctors agreed that their exposure to general practice had been insufficient for them to assess it as a career option, but this improved over time: agreement fell from 39% in 1999 to 28% in 2015. As a factor influencing specialty choice, enthusiasm for, and commitment to, the specialty was rated as very important by 65% of intending GPs in 2015, up from 49% in 1999; the corresponding figures for intending hospital doctors were 91% in 2015, up from 61% in 1999.ConclusionOver the 16 years covered by this study, the attractiveness of general practice has fallen relative to hospital practice. This may not necessarily reflect a decline in attractiveness of general practice in absolute terms; rather, it may reflect a greater increase, over time, in the appeal of hospital practice.
Healing incisional surgical wounds using Rose Hip oil in rats
Authors: Da Costa Cavalcante Lainy Carollyne , Prado Pessôa Thyago Cezar , Gonçalves Ribeiro Júnior Rubens Fernando , Yasojima Edson Yuzur , De Figueiredo Chaves Soares Rosa Helena , Henriques Brito Marcus Vinicius , Herbster Gouveia Eduardo Henrique , Nascimento Galvão Lucas , Rodrigues Ramos Suzana , Almeida Carneiro Adan Kristian , Amaral Serruya Yuri Aarão , Malta de Moraes Mateus 
Published: March 2017

Purpose: To evaluate incisional surgical wound healing in rats by using Rose Hip (Rosa rubiginosa L.) oil.
Methods: Twenty-one days after the oophorectomy procedure, twenty-seven female, adult, Wistar rats were distributed into three groups: Control group (wound treatment with distilled water); Collagenase group (treatment with collagenase ointment); and Rose Hip group (wound treatment with Rose Hip oil). Each group was distributed according to the date of euthanasia: 7, 14 and 21 days. The wound was evaluated considering the macroscopic and microscopic parameters.
Results: The results indicated differences in the healing of incisional wounds between treatments when compared to control group. Accelerated wound healing was observed in the group treated with Rose Hip oil in comparison to the control and collagenase, especially after the 14th day. Morphometric data confirmed the structural findings.
Conclusion: There was significant effect in topical application of Rose Hip oil on incisional surgical wound healing.
The Use Of Spikes Protocol In Cancer: An Integrative Review
Authors: De Sousa Fernando Henrique , Engrácia Valenti Vitor , P. Hamaji Mariana , De Sousa Carla Ap. P. , Garner David Matthew , Sawada Namie Okino 
Published: March 2017

This is an integrative review which aimed to evaluate the use of the SPIKES protocol in Oncology. We selected articles published in Medline and CINAHL databases between 2005-2015, in English, with the descriptors defined by the Medical Subject Headings (MeSH):cancer, neoplasms, plus the uncontrolled descriptor: protocol spikes.
Six articles met the inclusion criteria and were analyzed in full, three thematic categories were established: aspects inherent to the health care professional; Aspects related to the patient and aspects related to the protocol. The main effects of the steps of SPIKES protocol can provide the strengthening of ties between health professionals and patients, and ensure the maintenance and quality of this relationship.
The results indicate an important limiting factor for effective doctor-patient relationship, the little training provided to medical professionals communication of bad news, verified by the difficulty reported in this moment through interviews in the analyzed studies.
Portrait of leptospirosis in the State of Acre, Brazil
Authors: Cirilo Costa Eloizy Mariana Dias de Medeiros , Gomes Lucena Ivina , Alves de Medeiros Januário Kalina Ligia , Nunes Alves de Sousa Milena 
Published: March 2017

Introduction: Leptospirosis is an acute bacterial disease, that has global distribution and manifests itself in subclinical or asymptomatic way, having mild or severe conditions that can lead to the death of the patient.
Objective: To identify, among the municipalities of the state of Acre, Brazil, those with the highest incidence of leptospirosis between 2010 and 2015, and in addition, to determine the prevalence of this disease between the sexes.
Methods: Descriptive study, of documentary character, with epidemiological base and quantitative approach. It was made by available documents through the Department of Informatics of the Unified Health System of Brazil (DATASUS) and also by the Health Secretary of State of Acre (SESACRE). Variables were selected as sex, age and year of notification. Regarding the analysis, it is emphasized that it was quantitative and descriptive and the results were presented in tables built in Microsoft Word.
Results: It was found that the capital of the state of Acre, Rio Branco, led every year, contributing to the higher proportion of notifications related to leptospirosis. Regarding gender, there was a predilection for males and among age groups, the period of 20 to 39 years contributes to the greater number of cases of the disease.
Conclusion: Leptospirosis is a worldwide public health problem and in the state of Acre, the high rainfall, the agglomeration of low income combined with inadequate sanitation, collaborate to infestation of transmitters animals, providing high rates of the disease. Thus, it appears that these high numbers can probably be attributed to the ineffectiveness of preventive activities, as well as insufficient investment directed to social policies and infrastructure sectors.
Keywords: Infectious Disease. Leptospirosis. Prevalence. Incidence.