bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extractos por destilación de Origanum vulgare, Tradescantia spathacea y Zingiber officinale para el manejo de Moniliophthora roreri de Theobroma cacao
Authors: Tamayo España Luz Elena , Ramírez González Sandra Isabel , López Báez Orlando , Quiroga Madrigal Ricardo René , Espinosa Zaragoza Saúl 
Published: January 2018

El cacao es un cultivo de importancia económica, social y ambiental para el sureste mexicano y de gran renombre mundial dada la calidad de materia prima para la elaboración de chocolates. Sin embargo, existen varios factores que afectan la calidad de los granos de cacao, siendo las enfermedades la principal limitante. La moniliasis (Moniliophthora roreri) es la más peligrosa y destructiva del cultivo, y existen pocas alternativas para el manejo orgánico de esta enfermedad. Por ello, en el presente trabajo se evaluó el efecto inhibitorio de los extractos obtenidos por destilación de Origanum vulgare, Tradescantia spathacea y Zingiber officinale sobre M. roreri. Para lo cual se aisló el hongo en laboratorio; se elaboraron los extractos en planta fresca (300 g L-1 y 600 g L-1) y seca (45 g L-1 y 90 g L-1), cada uno obtenido en dos relaciones agua-alcohol (10:0 y 10:1). Se determinó la concentración mínima inhibitoria (CMI) evaluando crecimiento micelial, conidias totales y germinadas. Se realizó análisis de varianza y comparaciones de medias Tukey (p≤ 0.05%). Los resultados muestran que las tres plantas poseen metabolitos capaces de inhibir el crecimiento y formación de conidias a concentraciones de 50 y 40% tanto en planta fresca como seca, utilizando para la mejor extracción de sus metabolitos alcohol, y su CMI fue de 40%. Para la inhibición total del crecimiento y desarrollo de M. roreri para las tres plantas fueron más eficaces los extractos obtenidos a partir de 300 g de material fresco L-1 y como solvente agua-alcohol relación 10:1.
Comportamiento productivo de cinco variedades de alfalfa
Authors: Rojas García Adelaido Rafael , Hernández-Garay Alfonso , Joaquín Cansino Santiago , Maldonado Peralta María de los Ángeles , Mendoza Pedroza Sergio Iban , Álvarez Vázquez Perpetuo , Joaquín Torres Bertín Maurilio 
Published: January 2018

La alfalfa (Medicago sativa L.) es la leguminosa forrajera más utilizada en la alimentación del ganado productor de leche en los Estados Unidos de América y México. El objetivo de esta investigación fue evaluar la respuesta productiva de cinco variedades de alfalfa con intervalos de corte definidos estacionalmente. La investigación se realizó de junio de 2010 a junio de 2011 en el Colegio de Postgraduados, México. Las variedades comerciales evaluadas fueron: San Miguelito, Júpiter, Atlixco, Vía láctea y Cuf 101, las cuales se distribuyeron aleatoriamente en 20 parcelas experimentales de 12 por 9 m, de acuerdo a un diseño de bloques completos al azar con cuatro repeticiones. Las variables evaluadas fueron: tasa de crecimiento, radiación interceptada, índice de área foliar y altura de planta. Las variedades Júpiter y Cuf 101 con 56 y 37 kg MS ha-1 d-1 registraron la mayor y menor tasa de crecimiento, respectivamente. La variedad que mayor radiación interceptada registró fue Júpiter con un promedio anual de 85%; de la cual la distribución estacional a través del año fue 95% en primavera, 93% en verano, 82% en otoño y 80% en invierno. En la estación de verano se encontró el mayor índice de área foliar con 5.4, seguido de primavera, otoño e invierno con 4.4, 3.6 y 2.1, respectivamente.
En conclusión existe una relación positiva, en las cinco variedades de alfalfa, entre radiación interceptada, tasa de crecimiento, índice de área foliar y altura de planta.
Siembra de Cultivos Organopónicos como Praxis del Docente Centrado en Estrategias de Aprendizajes Motivacionales
Authors: Caldera Tovar Pedro Jacobo 
Published: January 2018

El objetivo fundamental de esta investigación es establecer la siembra de cultivos organopónicos como praxis del docente centrado en estrategia de aprendizaje motivacional dirigido a estudiantes para evitar el ausentismo escolar, además de identificar las causas y consecuencias de esta situación problemática, evidenciada en los registros de control llevados diariamente y se debe atender en virtud del ascenso de inasistencia estudiantil. El docente tutor, el coordinador de nivel, pedagogía social, bienestar estudiantil y representantes deben activar un plan en pro del cumplimiento de las normativas legales vigentes. El ausentismo escolar afecta la calidad del aprendizaje de los estudiantes trae como consecuencia el bajo rendimiento escolar, dificultad para comunicarse, debilidades en el trabajo de equipo y conflictos con la comunidad en general. Se busca promover en los estudiantes la participación en los procesos de aprendizaje, asistiendo permanentemente a las actividades escolares. Las estrategias utilizadas se enmarcaron en un plan de acción que incluye diferentes actividades. La metodología estuvo centrada en la investigación acción, centrados en la Teoría de los intereses constitutivos de saberes de Habermas (1968), con bases legales, aportando reflexiones conclusivas que permiten sensibilizar a la colectividad en general sobre esta debilidad que atenta contra la educación como una oportunidad para aprender ciencias, artes y oficios para la vida.
Formación Permanente de los Docentes como Referente de la Calidad Educativa
Authors: Peña Lozada Johana Carolina 
Published: January 2018

El presente artículo de revisión bibliográfica pretende hacer una reflexión para caracterizar la Formación Permanente de los Docentes como Referente de la Calidad Educativa, a través de una revisión documental, a fin de realizar una valoración del componente formación permanente bajo el esquema de la calidad educativa, el análisis apunta a consideraciones hechas por distintos autores, en los aspectos más relevantes, se hace notorio e imperativo la inclusión de políticas, planes y programas de acuerdo a la formación permanente del docente para la consecución de todos los objetivos que persigue la educación en los diferentes espacios que la conforman involucrando la praxis del docente en su accionar con miras a una mejor calidad educativa.
Pattern Of Hand Injuries in a Teaching Hospital of a Developing Country
Authors: Shrestha Kishor Man , Pandey A , Shrestha B 
Published: January 2018

INTRODUCTION: Hand injuries are common and are responsible for a significant hospital emergency visit and most of which are seen by non hand specialists. The pattern of the injuries varies from place to place. It is pertinent that those who may come across the patients understand this pattern. MATERIALS & METHODS: A retrospective review of records of patients presenting with hand injuries to the emergency unit and in OPD unit over two year period was carried out highlighting the pattern of the injury.RESULTS: The common cause of hand injury in these patients was fodder cutter machines which is 53 patients (30.6%) followed by industrial machines injury in 36 patients (20.8%), road traffic accidents in 30 patients (17.3%), physical assault in 19 patients (10.9%), threshing machines in 13 patients (7.5%), fall in 9 patients (5.2%), falling objects in 8 patients (4.6%), door injury in 2 patients (1.15%) and sports injury in 1 patient (0.5%). The injury was more common in young adults between 15 to 34 years of age with the mean age of 24.5 years. Most of the injury occurred during work by fodder cutter machine and industrial machines or other causes as road traffic accidents. In the present study, 17.3% cases had injury on Saturday comprising 80.9% of males and 53.1% of cases had fractures with high incidence of injury of the Right hand which was 53.7%. Most of the cases having fractures were of Gustilo II variety (28.2%) and 94.2% of cases were of minor to moderate grades of severity of hand injury on grading by HISS grading.CONCLUSION: Understanding the pattern of injury can impart positively on the management of hand injuries and for its preventive measures.Journal of Universal College of Medical Sciences (2017) Vol.05 No.01 Issue 15, page: 29-32
Utility of Serum Allergy Test In Patients With Chronic Urticaria
Authors: Bhattarai Sabina , Pradhan K , Sharma S , Pant AD 
Published: January 2018

INTRODUCTION: Chronic urticaria (CU) is a common skin disorder affecting 15– 20% of the people in the general population. It is a frequent disease which presents with wheals, angiooedema or both and lasts for over six weeks or more. OBJECTIVES: To determine the etiology of IgE specific allergens in the causative of CU in the Nepalese population. MATERIALS & METHODS: A prospective cross sectional study was carried out between November 2014- October 2016 on all patients diagnosed as having CU. Blood samples were taken from all patients and asemiquantitative determination of IgE antibodies against a panel of individual allergens was done and data analyzed and interpreted in terms of numbers and percentages. RESULTS: Three hundred and fourteen patients were included in the study with 56% (175) being female and 44% (139) being male. The age of the patients ranged from 5years to 84 years with a mean of 37.33± 14.39 years. The duration of the disease also ranged from 0.15 to 20 years in which 116(36.9%) patients presented with disease of less than 6 months duration while 163(51.9%) patients had the disease for more than 6 months. Two hundred and seventy nine patients (88.9%) showed a positive test to the allergens amongst which most were allergic to plants which included weeds and grass.CONCLUSION: In patients with CU whenever possible it is advisable to send the patient for serum allergy test to determine the causative agent, the avoidance of which can help in the management of urticaria in troublesome patients.Journal of Universal College of Medical Sciences (2017) Vol.05 No.01 Issue 15, Page: 33-36
Occupational Risk: Needle-Stick Injuries and Its Determinants Among the Healthcare Workers
Authors: Ghimire Madhusudan , Sharma Achala , Poudel Anuj , Ghimire Moushami 
Published: January 2018

INTRODUCTION: Needle-stick injuries are common problems among the healthcare workers; it might impact significantly on workers' health and health care delivery services. Sometimes small pinch of infected needle or sharp instrument may lead to big threat in their life and it may go into mortal outcomes.OBJECTIVE: To explore prevalence of needle-stick injuries and its determinants among the healthcare workers in Banke, Pyuthan and Palpa district of Nepal.MATERIALS & METHODS: A cross-sectional study was undertaken in 2015 and that focused on needle-stick injuries and its determinants. Data were collected by using an unstructured pre tested questionnaire from 359 healthcare workers. SPSS-21 windows process was used to analyze the information. RESULTS: Three hundred fifty-nine health care workers: Doctors (23.70%), Allied health workers (37.60%), Nurses (31.80%), and Laboratory staffs (7.00%) were involved in the study. The mean age of health workers was 32.75 ± 10.478 years. 37.60% of total healthcare workers had needle stick injuries.CONCLUSION: The prevalence of needle-stick injuries was associated strongly with age of healthcare workers, depression, social problems and alcohol consumer and, practice of sleepJournal of Universal College of Medical Sciences (2017) Vol.05 No.01 Issue 15, page : 45-48
Fracture of Proximal Humerus & Shaft Managed With Closed Reduction & External Fixation by Joshi External Stabilisation System (Jess) – A Case Report
Authors: Kandel Prakriti Raj , Baral Rajiv , Thakur Abhishek Kumar , Singh Gyaneshwar Prasad , Pathak Laxmi 
Published: January 2018

We are presenting a case of proximal humerus& shaft fracture in a 50 year old female. She sustained injury on her left upper limb in a road traffic accident. It was managed with closed reduction & external fixation by Joshi External Stabilisation System (JESS). Lacerated wound over her left shoulder & arm region was managed with skin grafting. The post-operative period was uneventful. Journal of Universal College of Medical Sciences (2017) Vol.05 No.01 Issue 15, Page: 54-58
Simultaneous Observation of a Flux Rope Eruption and Magnetic Reconnection during an X-class Solar Flare
Authors: Yan X. L. , Yang L. H. , Xue Z. K. , Mei Z. X. , Kong D. F. , Wang J. C. , Li Q. L. 
Published: January 2018

Abstract
In this Letter, we present a spectacular eruptive flare (X8.2) associated with a coronal mass ejection on 2017 September 10 at the west limb of the Sun. A flux rope eruption is followed by the inflow, the formation of a current sheet, and a cusp structure, which were simultaneously observed during the occurrence of this flare. The hierarchical layers of the cusp-shaped structure are well observed in 131 Å observation. The scenario that can be created from these observations is very consistent with the predictions of some eruptive models. Except for the characteristics mentioned above in the process of the flare predicted by classical eruption models, the current sheet separating into several small current sheets is also observed at the final stage of the flux rope eruption. The quantitative calculation of the velocities and accelerations of the inflow, hot cusp structure, and post-flare loops is presented. The width of the current sheet is estimated to be about 3 × 103 km. These observations are very useful in understanding the process of solar eruptions.
IL-10 Paradoxically Promotes Autoimmune Neuropathy through S1PR1-Dependent CD4+ T Cell Migration
Authors: Smith Collin-Jamal , Allard Denise E. , Wang Yan , Howard James F. , Montgomery Stephanie A. , Su Maureen A. 
Published: January 2018

Abstract
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a debilitating condition caused by autoimmune demyelination of peripheral nerves. CIDP is associated with increased IL-10, a cytokine with well-described anti-inflammatory effects. However, the role of IL-10 in CIDP is unclear. In this study, we demonstrate that IL-10 paradoxically exacerbates autoimmunity against peripheral nerves. In IL-10–deficient mice, protection from neuropathy was associated with an accrual of highly activated CD4+ T cells in draining lymph nodes and absence of infiltrating immune cells in peripheral nerves. Accumulated CD4+ T cells in draining lymph nodes of IL-10–deficient mice expressed lower sphingosine-1-phosphate receptor 1 (S1pr1), a protein important in lymphocyte egress. Additionally, IL-10 stimulation in vitro induced S1pr1 expression in lymph node cells in a STAT3-dependent manner. Together, these results delineate a novel mechanism in which IL-10–induced STAT3 increases S1pr1 expression and CD4+ T cell migration to accelerate T cell–mediated destruction of peripheral nerves.
Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway
Authors: Chatfield Simon M. , Grebe Kathrin , Whitehead Lachlan W. , Rogers Kelly L. , Nebl Thomas , Murphy James M. , Wicks Ian P. 
Published: January 2018

Abstract
Neutrophil extracellular traps (NETs) and the cell death associated with it (NETosis) have been implicated in numerous diseases. Mechanistic studies of NETosis have typically relied on nonphysiological stimuli, such as PMA. The human disease of gout is caused by monosodium urate (MSU) crystals. We observed that DNA consistent with NETs is present in fluid from acutely inflamed joints of gout patients. NETs also coat the crystals found in uninflamed tophi of chronic gout patients. We developed a quantitative, live cell imaging assay, which measures the key features of NETosis, namely, cell death and chromatin decondensation. We show that MSU and other physiologically relevant crystals induce NETosis through a molecular pathway that is distinct from PMA and Candida hyphae. Crystals interact with lysosomes to induce NADPH oxidase-independent cell death, with postmortem chromatin decondensation mediated by neutrophil elastase. The resulting MSU-induced NETs are enriched for actin and are resistant to serum and DNase degradation. These findings demonstrate a distinct physiological NETosis pathway in response to MSU crystals, which coats MSU crystals in DNA that persists in tissues as gouty tophi.
Connectivity in Hypergraphs
Authors: Dewar Megan , Pike David , Proos John 
Published: January 2018

AbstractIn this paper we consider two natural notions of connectivity for hypergraphs: weak and strong. We prove that the strong vertex connectivity of a connected hypergraph is bounded by its weak edge connectivity, thereby extending a theorem of Whitney from graphs to hypergraphs. We find that, while determining a minimum weak vertex cut can be done in polynomial time and is equivalent to finding a minimum vertex cut in the 2-section of the hypergraph in question, determining a minimum strong vertex cut is NP-hard for general hypergraphs. Moreover, the problem of finding minimum strong vertex cuts remains NP-hard when restricted to hypergraphs with maximum edge size at most 3. We also discuss the relationship between strong vertex connectivity and the minimum transversal problem for hypergraphs, showing that there are classes of hypergraphs for which one of the problems is NP-hard, while the other can be solved in polynomial time.
Feasibility of a Manualized Occupation-Based Diabetes Management Intervention
Authors: Carandang Kristine M. , Pyatak Elizabeth A. 
Published: January 2018

Abstract
OBJECTIVE. We investigated the feasibility and acceptability of an occupational therapy intervention targeting diabetes management for underserved young adults.
METHOD. Eight participants completed the intervention and a battery of assessments at baseline and after the intervention. At completion, the participants and occupational therapist were interviewed about their experiences with the study. Four categories of assessment questions were used to guide the study: process, resource, management, and scientific.
RESULTS. Successes included recruitment; fulfillment of tasks by staff and partnering clinics; adequate space, financial support, and equipment; and meaningfulness of the intervention for participants. Challenges included scheduling participants for the intervention and follow-up focus groups and providing client centeredness and flexibility while reducing burden on the intervener.
CONCLUSION. This feasibility study allowed us to make necessary revisions to our study protocol before implementing a larger pilot study.
Publication Productivity in the SCM Discipline: 2014–2016
Authors: Maloni Michael J. , Carter Craig R. 
Published: January 2018

AbstractGiven the relatively young age of the supply chain management (SCM) discipline, SCM academic programs must be able to validate their effectiveness to compete for university resources. The research herein supports this by extending a longstanding series that evaluates publication productivity across six major SCM journals. This edition ranks the top 25 most productive SCM schools between 2014 and 2016. With the series now celebrating 50 years, the results therefore allow evaluation of a half century of SCM research. The series also evaluates authorship concentration to assess the continued growth of the SCM discipline. Like previous editions, the results reveal that a core set of schools continue to lead SCM research with some holding strong performance throughout the entire 50 years. However, a moderately large portion of the top-25 schools continues to change as new SCM programs emerge globally. The author concentration analysis confirms these results as the growth of new scholars and new SCM programs continue to consistently expand. As a point of concern, however, the global diffusion of SCM authorship and schools graduating new SCM scholars are slowing.
Optimizing Area Coverage for Time-Differentiated Distribution: A Unidimensional Analysis
Authors: Jat Mohsin Nasir 
Published: January 2018

Abstract
This article studies the problem of optimally locating storage facilities and determining their service areas for the distribution of goods within multiple distance constraints. The problem is relevant for the service systems that maintain inventories of items required for servicing at demand locations within different service time windows (e.g., the after-sales service systems that maintain service parts for critical equipment). A location optimization model is presented that considers a continuous unidimensional coverage under two service distance constraints, demand composition, and inventory and transportation costs. The investigation primarily focuses on the tradeoff between inventory and transportation costs to provide guidelines for the appropriate distribution setups under a set of different conditions. The article adds to the under-researched area of continuous location optimization and offers some novel insights in this area. Some of the existing optimization methods in this area rely on Voronoi partitioning. However, the analysis highlights that Voronoi regions may not be optimum when inventory costs are considered. It also highlights that different cost and demand compositions can result in significantly different optimum location patterns.
Politiques de l’écriture et régimes du collectif dans les avant-gardes littéraires en mai-juin 1968
Authors: Gobille Boris 
Published: January 2018

Cet article explore l’impact de Mai-Juin 68 sur les avant-gardes littéraires françaises. La contestation paraît conforter les écrivains d’avant-garde dans leurs aspirations révolutionnaires. Mais elle les défie tout autant. Ils se doivent de descendre dans l’arène et de former des collectifs. Les politiques de la littérature avant-gardistes, du moins celles qui font reposer la révolution sociale sur une révolution dans le langage armée par le savoir théorique le plus avancé, sont contestées par la prise de parole généralisée, égalitaire, anonyme et profane. Comment les avant-gardes affrontent-elles ce défi ? Trois positions sont examinées. Tel Quel, hostile au mouvement étudiant, intervient comme groupe déjà constitué et réaffirme la coupure entre théoriciens spécialisés et profanes spontanéistes. À l’inverse, le Comité d’action étudiants-écrivains, formé le 18 mai 1968 dans la Sorbonne occupée, s’aligne sur la matrice symbolique de Mai, prône la fusion dans le mouvement révolutionnaire et la rupture avec les privilèges de l’écrivain, et bâtit un « communisme d’écriture » fondé sur l’anonymat et l’impersonnalité. Enfin, l’Union des écrivains, née elle aussi durant les événements, conteste « l’ordre littéraire établi » et interroge les rapports entre l’écriture littéraire et « l’écriture généralisée » de Mai. Elle construit en outre une action collective de type syndical qui, parce qu’elle pose que l’écrivain est un « travailleur » dont il faut empêcher la « mort sociale », rompt avec les mythologies littéraires présentant l’auteur comme un créateur éthéré et solitaire. Le régime de communauté politique propre à Mai-Juin 68 télescope donc le régime de singularité littéraire et contraint les avant-gardes à repenser à la fois leurs politiques de l’écriture et leurs conceptions du collectif. Cet article, qui souhaite contribuer à l’étude des rapports entre champ littéraire et événement critique, interroge enfin ce qu’il advient de ces remaniements dans l’immédiat après-Mai.