bluuebunny/crossref_metadata_2025_split huggingface dataset:
The End of a Custom: A Social Necessity or a Lust for “Modernisation”? The Case of Sergiani in Megala Kalyvia (Trikala, Greece)
Authors: Dimopoulos Konstantinos , Tyrovola Vasiliki , Koutsouba Maria 
Published: November 2017

AbstractThe custom as an act inherently includes the concept of compulsory repetition and expresses the community as a whole. Through custom and ritual, every local or wider community discovers its own identity, but also the ritual is the vehicle through which the inhabitants of the local community give shape to that identity and are influenced by it . The custom of sergiani was a cultural act performed by the inhabitants of the Megala Kalyvia municipality, as the latter forms part of the wider Karagkounides group. The aim of this paper is to shed light on the custom of sergiani performed in Megala Kalyvia (Trikala, Greece), as well as to emphasise on the reasons why the custom stopped being performed. The collection and processing of data is based on the principles of ethnographic study. The new socioeconomic, historical and cultural facts that prevailed let to the discontinuance of the custom and the accompanying dances, as it occurred with other cultural and dance practices, and it was sealed by the historical structure a dependent - in a broader sense - local social and cultural identity. The president of the municipality, as an expression of the occidental perception with foreign cultural influences contrary to the perceptions of its inhabitants, contributed, with his actions, to the alienation of the local cultural identity.
Crystal structure of 4-(4′-(pyridin-4-yl)-[1,1′-biphenyl]-4-yl)pyridin-1-ium catena-poly[{5-carboxy-4′-methyl-[1,1′-biphenyl]-3-carboxylato-κ2
O,O′}-(μ2-4′-methyl-[1,1′-biphenyl]-3,5-dicarboxylato-κ4
O,O′:O′′,O′′′)lead(II)], C52H40N2O9Pb
Authors: Song Wei , Li Shi-Hui , Xu Xue-Li 
Published: November 2017

Abstract
C52H40N2O9Pb, triclinic, P1̅ (no. 2), a = 10.3025(4) Å, b = 14.1740(9) Å, c = 16.0428(9) Å, α = 115.835(6)°, β = 97.680(4)°, γ = 90.493(4)°, V = 2083.7(2) Å3, Z = 2, R
gt(F) = 0.0342, wR
ref(F
2) = 0.0612, T = 293(2) K.
Radioiodination and biological evaluation of mesalamine as a tracer for ulcerative colitis imaging
Authors: Sanad M.H. , Talaat H.M. , Fouzy Ahmed S.M. 
Published: November 2017

Abstract
This study aims to evaluate newly radioiodinated mesalamine (Mes) as a tracer for ulcerative colitis imaging. Mes was labeled with [125I] with chloramine-T (Ch-T) as the oxidizing agent. Labeling factors such as pH, reaction temperature, reaction time, substrate amount and oxidizing agent amount were investigated to optimize the radiochemical yield (98.5%). The labeled compound was separated and purified using thin layer chromatography (TLC), paper electrophoreses and high performance liquid chromatography (HPLC). The biological distribution indicated that the radioiodinated mesalamine localization was highest (72.28%) in microbial model compared to normal mice (29.25%) at 120 min post injection. So, 125I-Mes could be considered as a new radiotracer for ulcerative colitis.
Proportional Representation, Large District Magnitude and Closed Lists
Authors: Buben Radek , Kouba Karel 
Published: November 2017

AbstractChoosing the type of electoral system in new democracies has become a contested issue for social scientists as well as for political actors. Contrary to the state of the public debate on the issue, the article advances the position from a multidisciplinary standpoint (political science, historical sociology, economics) that proportional representation with large districts and closed lists performs better on a variety of key indicators. We review recent literature on the performance of electoral systems especially in post-communist and Latin American democracies. The article identifies the centripetal theory of democracy as a normative basis for our institutional prescriptions and discusses how distinct types of political representation relate to the debate on electoral systems. We focus especially on four main concerns commonly associated with proportional representation (the rise of “extremist” parties, government instability, party system deconsolidation, and corruption and clientelism). Contrary to much of the public debate on electoral systems, we conclude that further steps towards personalization (by opening lists or reducing district magnitude) are not advisable.
Der Begriff der Substanz bei Marx
Authors: Ruschig Ulrich 
Published: November 2017

ZusammenfassungDurchsucht man Marxens Schriften daraufhin, wo und in welchem Zusammenhang ‚Substanz‘ vorkommt, dann stellt man irritiert zweierlei fest:– ‚Substanz‘ findet sich an zentralen Stellen und ist mit einem für die Marxsche Theorie grundlegenden Begriff, dem des Werts, in eminenter Weise verbunden – und obendrein mit dem des sich verwertenden Werts, dem des Kapitals.– Wiewohl der Begriff des Werts eine herausragende Rolle spielt, verwendet der so systematische Marx ‚Substanz‘ in auffälliger Weise uneinheitlich.Diese Uneinheitlichkeit sollte nicht als Marginalie eines misslicherweise ausgerechnet in diesem entscheidenden Punkt unklaren Autors abgetan werden. Sie hat vielmehr einen Grund in der Sache; kann die Uneinheitlichkeit geklärt werden, wird die Sache geklärt.In Marxens Texte gehen Bestimmungen des aristotelischen, eben metaphysischen Substanzbegriffs konstitutiv ein. Zugleich enthalten die Texte eine diesen Substanzbegriff als unwahr zurückweisende Kritik. Für Marxens Aufnahme des Hegelschen Substanzbegriffs, der ja nicht minder metaphysisch ist, gilt Analoges: So wesentlich Hegels Reflexionen über die Substanz für Marxens Kritik der politischen Ökonomie sind, so wesentlich ist zugleich die eine solche Substanz bestreitende Hegel-Kritik. Diese Antinomie ist – theoretisch – nicht zu schlichten, denn sie verdankt sich dem Gegenstand der Kritik der politischen Ökonomie, der kapitalistischen Produktionsweise. Mithin werden weder der Substanzbegriff noch die aufklärerische Kritik desselbigen überflüssig oder gar nichtig: Dialektik ergreift einen zentralen Begriff wie den der Substanz des Werts, der abstrakt menschlichen Arbeit. Deren Antinomie ist Anweisung auf Politik, spezieller den Eingriff in die Geschichte, den Griff des in dem gespenstigen Zug fortschreitender Kapitalakkumulation reisenden Menschengeschlechts nach der Notbremse.
Zur „Letalität“ des Kapitalozän – Anmerkungen zu Jason Moores Verständnis von Grenzen, kapitalistischen Gesellschafts- und Naturzusammenhängen sowie Ursachen von Krisen
Authors: Karathanassis Athanasios 
Published: November 2017

ZusammenfassungJason Moore thematisiert unterschiedliche Ebenen und Qualitäten von Grenzen und Trennungen als Angelpunkt der Entwicklung und Konstitution kapitalistischer Gesellschaften, womit auch die Bildung von Krisen und ihre Zusammenhänge in den Fokus rücken. Hierbei werden sowohl die sozial-ökonomischen Beziehungen als auch gesellschaftliche Naturverhältnisse im Kapitalismus als zusammenhängende Räume erkannt, in denen Grenzziehungen und somit Trennungen historisch-praktisch wirkmächtig werden.Moores Verweis auf herrschafts- bzw. machtkonstituierende Trennungen ist ein Kontrapunkt zu hegemonialen Diskursen und ein theoretischer Ansatzpunkt, der insbesondere mit der Aufhebung dieser Trennungen auch emanzipatorische Auswege aus dem Kapitalozän aufzuzeigen vermag.
Kontingenz und Dezision – (k)ein notwendiges Verhältnis?
Authors: Mokosch Bastian 
Published: November 2017

ZusammenfassungDer Begriff Kontingenz avancierte seit Mitte der 1990er Jahre zu einer Art Leitbegriff der Sozialwissenschaften und erreichte vor allem in Form der postmarxistischen These von der „Grundlosigkeit des Sozialen“ axiomatischen Status in linker Politik- und Sozialtheorie. Dass es vor allem mal explizit, mal latent dezisionistische Theorieprogramme waren, die dem Kontingenzbegriff zu erneuter Popularität verhalfen, ist die ideenhistorische Grundsituation, die im vorliegenden Beitrag als Problem gestellt wird und folgende Frage provozierte: sind die historisch gleichzeitigen Renaissancen von Kontingenz- und Dezisionsbegriff zufällig oder verweisen die Begriffe von Grund auf aufeinander und bilden ein notwendiges Verhältnis? Zunächst soll hierfür augezeigt werden, dass die Semantik des Kontingenzbegriffs durchaus vielschichtig ist und je nach theoretischem Kontext variiert. Zwei Extremformen werden dabei separiert. Eine dieser Extremformen des Begriffs, die gegenwärtig häufig gebrauchte, wird in einem zweiten Schritt als dem Dezisionismus entsprechende Kontingenz ausgewiesen. Zu guter Letzt wird diskutiert, warum dezisionistische Argumentationsketten für Theorien mit progressivem Anspruch überhaupt problematisch sind.
Singapore Sling: F1 Race Team Cognitive Function and Mood Responses During the Singapore Grand Prix
Authors: O'Neill Barry V. , Davies Kirsty M. , Morris-Patterson Tess E. 
Published: November 2017

Abstract
O'Neill, BV, Davies, KM, and Morris-Patterson, TE. Singapore sling: F1 race team cognitive function and mood responses during the Singapore grand prix. J Strength Cond Res 34(12): 3587–3592, 2020—The current investigation measured cognitive performance and subjective ratings of mood and sleep in Formula 1 (F1) race team members during the 2013 Singapore Grand Prix. Two weeks before the Singapore Grand Prix, subjects (n = 16; mean age 33.5 years, range 22–48 years) underwent baseline cognitive assessments and a questionnaire on mood and sleep quality/duration. These assessments were repeated on the race weekend before practice (S1) and after qualifying (S2). A significant increase in simple reaction time (SRT), i.e., slowing of total response time was observed from baseline to S1 (33.69 ± 6.52 ms; p < 0.001) and from baseline to S2 (34.63 ± 8.19 ms; p = 0.002). Mood-related effects were observed with subjective stress levels increased from baseline to S1 (18.06 ± 6.18; p = 0.032) and a decrease in how refreshed the race team members felt between S1 and S2 (18.56 ± 6.14; p = 0.029). In addition, a negative association between change in SRT and change in quality of sleep (R
2 = 0.47; p = 0.016) as well as negative association in how refreshed individuals reported feeling and SRT between S1 and S2 (R
2 = 0.37; p = 0.017). The findings suggest that the demands presented by an F1 race environment have significant effects on cognitive function and mood; however, the exact cause of any decrements would most likely be a combination and interaction of multiple factors. Future research should endeavor to adopt a holistic approach and investigate physiological and cognitive endpoints to fully explore the demands of this challenging motor sport.
A Neural Signature Encoding Decisions under Perceptual Ambiguity
Authors: Sun Sai , Yu Rongjun , Wang Shuo 
Published: November 2017

AbstractPeople often make perceptual decisions with ambiguous information, but it remains unclear whether the brain has a common neural substrate that encodes various forms of perceptual ambiguity. Here, we used three types of perceptually ambiguous stimuli as well as task instructions to examine the neural basis for both stimulus-driven and task-driven perceptual ambiguity. We identified a neural signature, the late positive potential (LPP), that encoded a general form of stimulus-driven perceptual ambiguity. In addition to stimulus-driven ambiguity, the LPP was also modulated by ambiguity in task instructions. To further specify the functional role of the LPP and elucidate the relationship between stimulus ambiguity, behavioral response, and the LPP, we employed regression models and found that the LPP was specifically associated with response latency and confidence rating, suggesting that the LPP encoded decisions under perceptual ambiguity. Finally, direct behavioral ratings of stimulus and task ambiguity confirmed our neurophysiological findings, which could not be attributed to differences in eye movements either. Together, our findings argue for a common neural signature that encodes decisions under perceptual ambiguity but is subject to the modulation of task ambiguity. Our results represent an essential first step toward a complete neural understanding of human perceptual decision making.
The influence of phacoemulsification on various corneal layers in patients with pseudoexfoliation syndrome assessed with confocal in vivo microscopy
Authors: Potemkin Vitaly V. , Varganova Tatyana S. , Terekhova Irina V. , Ageeva Elena V. 
Published: November 2017

Phacoemulsification (PHACO) is the basic procedure of cataract extraction.
Purpose. To assess the impact of PHACO on corneal epithelium layers in patients with pseudoexfoliation syndrome (PEX) by confocal in vivo microscopy.
Methods. 24 patients with PEX syndrome and 18 patients without it were enrolled in the prospective study. In vivo confocal microscopy was performed with assessment of cellular density in corneal epithelial layers, degree of its desquamation, degree of Bowman membrane stiffening and dendritic cells density.
Results. The epithelial cells density didnt change significantly in groups. Confocal microscopy showed high density of dendritic cells and marked desquamation of the epithelium in patients with PEX (p 0,05) after PHACO.
Scleral capsule biophysical properties in the prognosis of the stabilizing effectiveness of orthokeratological myopia correction
Authors: Tarutta Yelena P. , Iomdina Yelena N. , Toloraya Rusadani R. , Kruzhkova Galina V. 
Published: November 2017

Purpose: determine the impact of biophysical properties of the scleral capsule on the stabilizing effect of orthokeratological correction in progressive myopia.
Material and methods. In 57 patients (114 eyes) aged 8-18 (average age 12.5 0.6 years) with myopia from 1.0 to 7.0 D, acoustic scleral density (ASD) was tested. All patients used (during different terms) orthokeratological (OK) lenses Contex OKE-System during the night time. To measure ASD (in conventional units) we used digital analysis of ultrasound tissue histograms obtained with a multifunctional ultrasound diagnostic device Voluson 730 Pro (Kretztechnik AG) with a linear frequency sensor of 10 to 16 mHz. ASD was measured in the posterior pole and in the superior temporal quadrant of the equatorial zone. The anteroposterior axis (APA) was measured by ultrasound biometry using an ultrasound device A/B Scan System Model 837 (Allergan Humphrey, USA). Myopia progression was found in 18 eyes of 9 patients with APA increase over 0.1 mm in 6 months, i. e. in 15.5% of cases, while the remaining 48 patients (96 eyes) showed no myopia progression over the follow-up period.
Results. APA was less in eyes with progressive myopia as compared to those with stabilized myopia, both in the equatorial and the posterior pole zones. In progressive myopia, mean APA was 213 3.6 units in the posterior pole and 208 2.19 units in the equatorial zone. In cases of stable myopia, APA was 2.1% higher in the posterior pole area (217 1.3 units) and 1.86% higher in the equatorial area (212 1.4 units). On average, APA in stable myopia was 4 2.0 units higher than in progressive myopia (р 0.05).
Conclusion. The APA parameter could serve as a prognostic criterion for the myopia course by OK-correction, and as an indicator for choosing treatment tactics.
Adli Olgu Bildirimiyle İlgili İkilemlerde Hekimlerin Tutumları
Authors: Can İsmail Özgür , Direk Neşe , Özdemir Mehmet Hakan 
Published: November 2017

Introduction: Double liability of health professionals occurs in situations in which decleration of forensic case is required. Medical doctors may experience conflicts between legislation and ethical principles. In this study, we aimed to explore the level of knowledge about forensic case declaration of medical doctors working at the XXX Medical Center. Also, we aimed to determine their attitudes and behaviours towards the situations in which ethical principles and legislation conflict is present to their knowledge.
Methods: We used a 22-item questionnaire including items to evaluate the definition of a forensic case, liability of declaration of forensic case, knowledge about legislation and ethical principles, attitudes and behaviour towards the conflicting situations. In total, 106 medical doctors were evaluated.
Results: Sixty-two percent of medical doctors follow legislation and 35% of them follow ethical principles when they face with conflicting situations.
Discussion: We discussed situations in which medical and ethical principles contradict and agree with legislation. We believe that such discussion would be helpful to attitude changes in conflicting situations.
PHARMACOLOGICAL THERAPY OF HEPATOCELLULAR CANCER PRACTICAL ISSUES AND SOLUTIONS
Authors: Breder V. V. , Laktionov K. K. , Davydov M. I. 
Published: November 2017

Pharmaceutical therapy of hepatocellular carcinoma represents a major clinical issue of debate in modern oncology. Until now, Sorafenib remains the only option for the management of locally advanced and metastatic hepatocellular carcinomas, which increases the overall survival of patients. In the absence of alternative treatment, the oncologist understanding of the place, time, the strategic goal and tactical objectives of the pharmaceutical therapy of hepatocellular carcinoma at different stages of cancer is of great importance. The article considers the practical aspects of the Sorafenib therapy of hepatocellular cancer in various clinical situations, and proposes algorithms of accompanying therapy for the underlying liver pathology. It presents the results of Regorafenib therapy, a new multi-kinase inhibitor, which significantly increases survival in the second line therapy of sorafenib-resistant hepatocellular carcinoma. The options of pharmaceutical therapy for hepatocellular carcinoma using cytotoxic and molecular-directed medicines, prospects of modern immunotherapy are discussed.
THE EFFICACY OF POSACONAZOLE FOR PROPHYLAXIS OF INVASIVE MYCOSES IN PATIENTS WITH ACUTE MYELOID LEUKEMIA
Authors: Klyasova G. A. , Okhmat V. A. , Parovichnikova E. N. , Gribanova E. O. , Troitskaya V. V. , Savchenko V. G. 
Published: November 2017

Efficacy of posaconazole for prophylaxis was evaluated in 77 chemotherapy cycles in 59 patients with acute myeloid leukemia (AML) aged 39 (17–62) years from 2012 till 2017. Posaconazole was given in oral suspension 200 mg three times a day after meal during chemotherapy cycle or on 1st day after the cycle. Administration of posaconazole predominated in patients with de novo AML (84.5%) on 1st induction cycles (66.3%). Neutropenia was present in all patients with median duration of 22 days. Median duration of prophylaxis was 21 (2–57) days. Posaconazole prophylaxis was interrupted in 28 (36.4%) of 77 cases, mainly due to diarrhea (28.6%). In 17 (61%) of 28 cases prophylaxis was resumed within a median of 3 days. In 72 (93.5%) of cases duration of posaconazole prophylaxis was ≥ 7 days, in 5 (6.5%) cases < 7 days. Efficacy of prophylaxis was evaluated in cases of posaconazole duration ≥ 7 days. Invasive pulmonary aspergillosis (probable) was in 2 (2.7%) of 72 cases. Administration of posaconazole with duration ≥ 7 days was in 46 cases on chemotherapy cycle, in 26 cases – on first day after the cycle. Patients using Posaconazole after a course of chemotherapy in comparison with patients receiving the drug in the first days of the course had significantly less interruptions of prophylaxis (11,5% vs 41,3%, p=0.009) and a reduction in duration of Posaconazole using (19 days vs 27 days, p=0.007).One case of invasive aspergillosis was registered in each group.We confirmed the efficacy of posaconazole for prophylaxis of invasive mycoses in patients with AML. Administration of posaconazole prophylaxis on first day after the end of chemotherapy cycle results in saving of drug by reducing duration of posaconazole using by 8 days and does not increase the incidence of invasive mycoses.
REAL-LIFE CLINICAL UTILITY OF RAMUCIRUMAB FOR THE TREATMENT OF PATIENTS WITH DISSEMINATED GASTRIC ADENOCARCINOMA: PRELIMINARY REVIEW OF THE EXPERIENCE OF BLOKHIN RUSSIAN CANCER RESEARCH CENTRE
Authors: Besova N. S. , Titova T. A. , Gorbunova V. A. , Gordeeva O. O. , Tryakin A. A. , Snegovoy A. V. , Nasyrova R. Yu. , Rumyantsev A. A. , Voroshilova E. A. , Artamonova E. V. 
Published: November 2017

Angiogenesis has become an important target in the treatment of solid tumors and anti-angiogenic agents are a promising approach to cancer therapy. Ramucirumab, an anti-angiogenic agent specifically targeting vascular endothelial growth factor receptor-2 (VEGFR-2). In April 2014, the FDA approved ramucirumab as a single agent or in combination with paclitaxel for treatment of advanced gastric or gastroesophageal junction adenocarcinoma (GC) that has progressed on or after prior fluoropyrimidine – or platinumcontaining chemotherapy based on data of REGARD and RAINBOW trials.We evaluated the progression free (PFS), overall survival (OS) and safety of ramucirumab in patients (pts) with advanced GC in routine clinical practice From June 2016 to 20 Sep 2017 40 pts with advanced GC were treated with ramucirumab in the second line treatment as single agent (8 pts) or in combination with paclitaxel (26 pts) in N.N.Blokhin National medical research center of oncology.Median PFS (MPFS) and median OS (MOS) was 1,8 and 7,6 mons for monotherapy group. For combination group MPFS was 5,02 mons, MOS was not reached. Ramucirumab had an acceptable safety profile Our data are similar to the data of REGARD and RAINBOW trials.
CLINICAL CASE OF SUCCESFUL APPLICATION OF KADSYLA APPLICATION IN METASTATIC HER2 POSITIVE BREAST CANCER
Authors: Sakaeva D. D. 
Published: November 2017

A clinical case of trastuzumab emtansine in therapy line 4 in patient with metastatic HER2positive breast cancer is provided. After 10 courses of targeted therapy by the drug a complete response to the therapy was obtained. By results of PET CT conducted in the period from December 2015 to September 2017 the complete response is preserved.
Structure modal optimization of a strapdown inertial navigation system for an electric helicopter using an adaptive surrogate model
Authors: Guo Shuzhen , Zheng Xiangming , Ang Haisong 
Published: November 2017

The purpose of this research is to prove the eventuality of using a novel adaptive surrogate model for optimization problems. The adaptive surrogate model is based on iteration sampling and extended radial basis function (ERBF). This method improves the precision by a means that new sample points is placed in the blank area and all the sample points is uniformly distributed in the design region. The precision of the surrogate model is checked using standard error measure to determine whether updating the surrogate model or not. Since the prediction of modal frequencies require structure modal simulations. In order to decrease the number of computer simulations, a Multi-Island GA approach is combined with the adaptive surrogate model to find the optimum modal frequencies of a strapdown inertial navigation system for electric helicopters. The strapdown inertial navigation system is comprised of damping material, counterweight material and inertial navigation sensor. This is a multi-objective functions optimization problem since the modal frequencies are considered from mode 1 to mode 6 in this paper. Several weights of multi-objective functions are utilized to research the modal frequencies. The whole number of 15 sampling points is picked to build the primary surrogate model using Latin hypercube sampling (LHS). The results of adaptive surrogate model show that two new sampling points are needed to reform the precision of the surrogate model under the condition of 2 % confidence bounds. The structure modal optimization results show that the choice of the weights for the multi-objective functions has a major effect on the final optimum modal frequencies. Time- and frequency-domain analysis indicated that the optimum modal frequencies are far away from the excitation frequencies to avoid strapdown inertial navigation system resonance as far as possible.