bluuebunny/crossref_metadata_2025_split huggingface dataset:
PASAR TENAGA KERJA KABUPATEN BANGKALAN
Authors: Wijanarko Andri , Chrismardani Yustina 
Published: October 2016

<p>Kabupaten Bangkalan is a gateway that has been connected Madura island with Surabaya City, the capital city of East Java Province, through Suramadu bridge. This study investigates the pattern of labor demand in Bangkalan. The pattern of labor demand is very important to be known, especially by Division of Social, Manpower and Transmigration Bangkalan, the authorized which provide guidance and address the labor problems</p><p>The method used is technically primary data collection through surveys and interviews to the company (employer) in five main districts, namely District of Bangkalan, District of Socah, District of Kamal, District of Labang and District of Burneh. The purpose of this study to know the pattern of demand for labor in Bangkalan so that The Bangkalan Agency of Social, Manpower and Transmigration can use the results of such research in developing planning strategies more better targeted.</p>Based on the survey, in 2016 is expected to increase the labor demand at high school education level who initially was balanced between primary education and highschool education level of workers. Likewise, in 2017 and 2018 was still dominated by the high school education level of workers, followed by undergraduate level. Recommendations from this study is the need for attention and follow-up of the The Bangkalan Agency of Social, Manpower and Transmigration to be able to open a Training Center more in some locations, especially Training Centre at the district level to train the workforce skills at the level of high school education, and implement the Job Fair in order to facilitate labor undergraduate level to get a job.
Deriving Effective Soil Water Retention Characteristics from Shallow Water Table Fluctuations in Peatlands
Authors: Dettmann Ullrich , Bechtold Michel 
Published: October 2016

Core Ideas
This is a new approach for determining in situ peat soil water retention characteristics.
It only requires data on water table changes, precipitation, and microrelief.
Water table rises are used to invert for water retention parameters.
Applicability is demonstrated for field data from a peatland.
This approach should be applicable to other shallow groundwater systems.We have developed a novel and simple approach that can be used to derive effective in situ soil water retention characteristics from field monitoring time series in peatlands. The simplicity of the approach is given by the very limited data requirements, which comprise only precipitation, water table, and, if relevant, microrelief data. Our approach is built on two main assumptions: (i) for shallow groundwater systems, the soil moisture profile is always close to hydrostatic equilibrium; and (ii) during short time periods of high precipitation, the water storage change due to lateral fluxes is small compared with the precipitation input. Given these assumptions, the height of a water table rise due to a precipitation event mainly depends on the soil water retention characteristics, the precipitation amount, the initial water table depth, and, if present, the microrelief. In this study, this dependency was used to determine the effective van Genuchten parameters by Bayesian inversion assuming a uniform soil profile. We applied our concept to field data from a peatland with microrelief. Results indicated that observations of water table rises caused by precipitation events can contain sufficient information to constrain the soil water retention characteristics around monitoring wells in peatlands to plausible ranges. In principle, the approach should also be applicable to other shallow groundwater systems. Application limits and potential systematic errors are discussed.
Giovanna Borradori: The American Philosopher. Conversations with Quine, Davidson, Putnam, Nozick, Danto, Rorty, Cavell, McIntyre and Kuhn. Transl. by Rosanna Crocitto. The University of Chicago Press. Chicago 1994. 178 pp.
Authors: Rivera José Luis 
Published: October 2016

Giovanna Borradori: The American Philosopher. Conversations with Quine, Davidson, Putnam, Nozick, Danto, Rorty, Cavell, McIntyre and Kuhn. Transl. by Rosanna Crocitto. The University of Chicago Press. Chicago 1994. 178 pp.
Por que a mídia é tão parcial e adversária da minha posição? A hipótese da "hostile media perception"
Authors: Gomes Wilson 
Published: October 2016

<em>O trabalho discute o muito disseminado sentimento, que afeta os membros de certos grupos e em certas circunstâncias, de que os meios de comunicação são tendenciosos contra o nosso lado e favorecem o lado adversário, assim como os mecanismos que lhe são subjacentes. Este ensaio tem como foco a sensação, convicção ou opinião, compartilhada por pessoas altamente envolvidas com certos temas ou assuntos, de que os conteúdos e abordagens da mídia são tendenciosos e adversários se e quando incongruentes com o ponto de vista ideológico, político ou religioso do próprio sistema de referências intelectual, moral e afetivo. Para tanto, o artigo resenha os argumentos mais constantes nos quase trinta anos de literatura especializada sobre a “hostile media perception” (HMP), modelo teórico-metodológico importante no campo dos estudos dos efeitos da comunicação, resumindo pontos de vista e apontando direções da pesquisa. </em>
Un médicament « monstrueux » : débats publics et couverture médiatique de la tragédie de la thalidomide au Canada, 1961–1963
Authors: Baillargeon Denyse , Commend Susanne 
Published: October 2016

Cet article s'attarde au drame de la thalidomide qui a frappé le Canada en 1962. S'appuyant sur divers documents d'archives, y compris des lettres envoyées au ministre fédéral de la Santé par des citoyens et citoyennes, et sur la couverture de la tragédie par les médias, il cherche principalement à analyser les débats que la naissance des bébés phocomèles ont provoqués afin de mieux cerner la conception que les sociétés canadienne et québécoise se faisaient des personnes handicapées au début des années 1960. Inspirée de la grille de classification développée par la philosophe française Marie-Claire Cagnolo au sujet des « logiques » qui ont présidé au traitement de ces personnes à travers l'histoire, l'étude conclut qu'une « logique séparatiste d'élimination » s'est alors clairement manifestée, en même temps qu'une « logique paternaliste de réparation » se faisait jour, mais sans que n'apparaisse une « logique sociétale d'intégration » qui aurait exigé de considérer le sort de tous les enfants handicapés, et pas seulement des bébés thalidomidiens, comme ce fut le cas.
The Currency of Consciousness: Neurology, Specialization, and the Global Practices of Medicine
Authors: Casper Stephen T. 
Published: October 2016

This article explores the formation of a global community of neurologists between 1918 and 1970. Relying chiefly upon documents located in Anglo-American archives, its argument follows a narrative from money to memory, and posits that this global community of neurologists formed not out of a shared science and medicine of the nervous system, but out of shared dispositions in tastes, values, and culture. The localism and heterogeneity of the science and medicine of the nervous system was in fact so pronounced that neurologists – especially when they worked as “global citizens” – were forced to focus upon their superficial commonalities rather than examine local distinctions. This avoidance of a direct effort to define the content of neurology – or at least to confront their differences – exercised a peculiar influence on the specialty. Neurologists and their “official memory” became negotiated, and even imagined constructs. Consequently, these diverse cultures were ultimately subordinated to dominant economic interests.
Lithium posttreatment confers neuroprotection through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats
Authors: Zheng Jian , Liu Zhen , Li Weishan , Tang Jiaxin , Zhang Dongwei , Tang Xiaobo 
Published: October 2016

OBJECTIVEInflammation and apoptosis are two key factors contributing to secondary brain injury after intracerebral hemorrhage (ICH). The objective of this study was to evaluate the effects of lithium posttreatment on behavior, brain atrophy, inflammation, and perihematomal cell death. Furthermore, the authors aimed to determine the role of the pro-apoptotic glycogen synthase kinase-3β (GSK-3β) after experimental ICH.METHODSMale Sprague-Dawley rats (n = 108) were subjected to intracerebral infusion of semicoagulated autologous blood. Window of opportunity and dose optimization studies of lithium on ICH-induced injury were performed by measuring neurological deficits. Animals with ICH received vehicle administration or lithium posttreatment (60 mg/kg) for up to 21 days. Hemispheric atrophy was evaluated. Perihematomal cell death was quantified through terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labeling (TUNEL). The number of myeloperoxidase (MPO)-positive neutrophils and OX42-positive microglia in the perihematomal areas were calculated. Western blotting was used for the quantification of GSK-3β, heat shock protein 70 (HSP70), nuclear factor-κB p65 (NF-κB p65), and cy-clooxygenase-2 (COX-2).RESULTSLithium, at a dose of 60 mg/kg initiated from 2 hours after injury, exhibited the best effects of improving neurological outcomes 3, 5, 7, 14, 21, and 28 days after ICH, reduced the hemispheric atrophy at 42 days after surgery, and reduced the number of TUNEL-positive cells, MPO-positive neutrophils, and OX42-positive microglia in the perihematomal areas. Furthermore, lithium posttreatment modulated GSK-3β, increased HSP70, and decreased NF-κB p65 and COX-2 expression in the ipsilateral hemisphere.CONCLUSIONSLithium posttreatment at a dose of 60 mg/kg, initiated beginning 2 hours after injury, improves functional and morphological outcomes, and inhibits inflammation and perihematomal cell death in a rat model of semicoagulated autologous blood ICH through inactivation of GSK-3β.
Activation of peroxisome proliferator-activated receptor–γ by a 12/15-lipoxygenase product of arachidonic acid: a possible neuroprotective effect in the brain after experimental intracerebral hemorrhage
Authors: Xu Ruobing , Wang Shu , Li Weishan , Liu Zhen , Tang Jiaxin , Tang Xiaobo 
Published: October 2016

OBJECTIVEIn this study, the authors investigated the involvement of 15(S)-hydroxyeicosatetraenoic acid (15(S)-HETE) in the regulation of peroxisome proliferator-activated receptor–γ (PPARγ) after intracerebral hemorrhage (ICH) and its effects on hemorrhage-induced inflammatory response and oxidative stress in an experimental rodent model.METHODSTo simulate ICH in a rat model, the authors injected autologous whole blood into the right striatum of male Sprague-Dawley rats. The distribution and expression of 12/15-lipoxygenase (12/15-LOX) were determined by immunohistochemistry and Western blot analysis, respectively. Immunofluorescent double labeling was used to study the cellular localization of 12/15-LOX, and 15(S)-HETE was measured with a 15(S)-HETE enzyme immunoassay kit. Neurological deficits in the animals were assessed through behavioral testing, and apoptotic cell death was determined with terminal deoxynucleotidyl transferase–mediated biotinylated dUTP nick-end labeling.RESULTSRats with ICH had increased expression of 12/15-LOX predominantly in neurons and also in oligodendrocytes, astrocytes, and microglia. Moreover, ICH elevated production of 15(S)-HETE in the brain area ipsilateral to the blood injection. The PPARγ agonist, exogenous 15(S)-HETE, significantly increased PPARγ protein levels and increased PPARγ-regulated gene (i.e., catalase) expression in the ICH rats. Reduced expression of the gene for the proinflammatory protein nuclear factor κB coincided with decreased neuron damage and improved functional recovery from ICH. A PPARγ antagonist, GW9662, reversed the effects of exogenous 15(S)-HETE on the PPARγ-regulated genes.CONCLUSIONSThe induction of 15(S)-HETE during simulated ICH suggests generation of endogenous signals of neuroprotection. The effects of exogenous 15(S)-HETE on brain hemorrhage–induced inflammatory responses and oxidative stress might be mediated via PPARγ.
Household Air Pollution from Cooking Fuels: An Environmental and Public Health Challenge
Authors: Joon Vinod , Chandra Avinash 
Published: October 2016

Cooking is central to our lives. Nearly 40% of the world population and about half of population of developing countries of Asia, Africa and Latin America rely on biomass fuels for their cooking energy needs and 84% of them reside in rural areas. When used in simple cooking stoves, these fuels emit substantial amounts of toxic pollutants that include respirable particles, carbon monoxide, oxides of nitrogen and sulfur, benzene, formaldehyde, 1,3-butadiene, and poly aromatic compounds. In households with limited ventilation as is common in rural household of developing countries, exposures experienced by household members have been measured to be many times higher than World Health Organization’s indoor air quality guidelines. Due to customary role of woman in cooking, she is exposed more. As children are often carried on their mother’s back or lap while the cooking is in progress, they are also exposed to high levels of cooking smoke and therefore are at risk of getting respiratory problems. Research studies give moderate to strong evidence linking household air pollution with chronic lung and other diseases making it a major public health problem of poor nations where it accounts for much of morbidity and over a million deaths annually. Also, fuel gathering adds time and transport burden on women and children, limiting their time for education and other productive work. In addition to health risks, incomplete combustion of biomass fuels are also responsible for greenhouse gas emissions which are the key environmental concern for climate change today.
Antitumor effects of iridomyrmecin in HeLa cervical cancer cells are mediated via apoptosis induction, loss of mitochondrial membrane potential, cell cycle arrest and down-regulation of PI3K/Akt and up-regulation of lncRNA CCAT2 expression
Authors: Lin Li , Cheng Xiao-Ling , Li Ming-Zhe , Wang Tao , Dong Min-Hai , Wang Zhen-Yu , Liao Min 
Published: October 2016

<p class="Abstract">The main purpose of the current study was to study the antitumor effects of iridomyrmecin against human cervical cancer cells (HeLa). Its effects on apoptosis induction, cell cycle phase distribution, PI3K/Akt signalling pathway and long non-coding RNA (lncRNA) were also investigated. Cytotoxic effects of iridomyrmecin were evaluated by MTT assay while the apoptotic effect was assessed by flow cytometry using annexin V-FITC assay. Western blot assay was used to study effects on PI3K/Akt signalling pathway. Results exhibited that iridomyrmecin led to concentration-dependent as well as time-dependent growth inhibitory effects. Iridomyrmecin-treated cells showed signs of early and late apoptosis. Iridomyrmecin treatment also led to sub-G1 cell cycle arrest as well as induced loss of mitochondrial membrane potential (ΔΨm). Further, Western blot assay revealed that iridomyrmecin treatment resulted in down-regulation of PI3K/Akt protein expressions in a dose-dependent manner while as it up-regulated lncRNA CCAT2 expression.</p><p class="Abstract"><strong>Video Clip</strong>:</p><p class="Abstract"><a href="https://youtube.com/v/4mKwQAi3Qbk">Flow cytometry for cell cycle analysis</a>: 3 min 20 sec</p><p> </p>
Combined tibial plateau levelling osteotomy and tibial tuberosity transposition for treatment of cranial cruciate ligament insufficiency with concomitant medial patellar luxation
Authors: Leonard Katherine , Kowaleski Michael , Saunders William , McCarthy Robert , Boudrieau Randy 
Published: October 2016

SummaryObjectives: To describe the surgical technique and report short-term outcome for combined tibial plateau levelling osteotomy and tibial tuberosity transposition (TPLO-TTT) as an option in the treatment of cranial cruciate ligament insufficiency with concomitant medial patellar luxation.Methods: Medical records were reviewed (2011–2013) of dogs that underwent a standard tibial plateau levelling osteotomy followed by a tibial tuberosity transposition in the frontal plane and stabilized with pin and tension-band wire fixation as a component of surgical treatment for combined cranial cruciate ligament insufficiency and medial patellar luxation. Signalment, fixation method together with any ancillary procedures, function at the in-hospital follow-up examinations, and any complications were recorded. Healing was assessed retrospectively based on the grading criteria of the International Society Of Limb Salvage.Results: Fifteen stifle joints in 11 dogs were identified; 13 stifles were available for in hospital follow-up. All 13 achieved union (3 with grade III/IV and 10 with grade IV/IV radiographic healing scores); mean time to healing was 10.6 (± 2.9) weeks. Patellar ligament thickening was also identified radio-graphically in seven of the 13 of stifle joints. All dogs were reported to have mild or no lameness at their last follow-up examination. No catastrophic or major postoperative complications occurred that required additional surgery. Patellar re-luxation did not occur in any of the 13 stifles available for in-hospital follow-up.Clinical significance: The TPLO-TTT was found to be a reliable and effective technique when used as a part of the treatment of combined cranial cruciate ligament insufficiency with concomitant medial patellar luxation in this series of dogs.Supplementary Material to this article is available online at http://dx.doi.org/10.3415/VCOT-15-12-0195.
Clinical, radiographic, and magnetic resonance imaging findings of gastrocnemius musculotendinopathy in various dog breeds
Authors: Harms Oliver , Konar Martin , Staudacher Anne , Langer Anna , Thiel Cetina , Kramer Martin , Schaub Sebastian , von Pückler Kerstin , Kaiser Susanne 
Published: October 2016

SummaryObjectives: To describe clinical, radio-graphic, and magnetic resonance imaging (MRI) findings in 16 dogs diagnosed with gastrocnemius musculotendinopathy.Methods: Retrospective evaluation of medical records, radiographs, and MRI results, as well as follow-up completed by telephone questionnaire.Results: Most dogs had chronic hindlimb lameness with no history of trauma or athletic activities. Clinical examination revealed signs of pain on palpation without stifle joint instability. Seven dogs had radiographic signs of osteophyte formation on the lateral fabella. Magnetic resonance imaging revealed T2 hyperintensity and uptake of contrast agent in the region of the origin of the gastrocnemius muscle. Changes were found in the lateral and medial heads of the gastrocnemius. Conservative treatment resulted in return to full function in 11 dogs. Two dogs showed partial restoration of normal function, one dog showed no improvement. Two dogs were lost to follow-up.Clinical significance: Gastrocnemius musculotendinopathy is a potential cause of chronic hindlimb lameness in medium to large breed dogs. A history of athletic activity must not necessarily be present. Magnetic resonance imaging shows signal changes and uptake of contrast agent in the region of the origin of the gastrocnemius muscle. A combination of T1 pre- and post-contrast administration and T2 weighted sequences completed by a fat-suppressed sequence in the sagittal plane are well-suited for diagnosis. Conservative treatment generally results in return to normal function.Supplementary Material to this article is available online at http://dx.doi.org/10.3415/VCOT-16-01-0015.
Characterization of polymorphic microsatellite markers in Pinus armandii (Pinaceae), an endemic conifer species to China
Authors: Dong Wan‐Lin , Wang Ruo‐Nan , Yan Xiao‐Hao , Niu Chuan , Gong Lin‐Lin , Li Zhong‐Hu 
Published: October 2016

Premise of the study:Pinus armandii (Pinaceae) is an important conifer tree species in central and southwestern China, and it plays a key role in the local forest ecosystems. To investigate its population genetics and design effective conservation strategies, we characterized 18 polymorphic microsatellite markers for this species.Methods and Results:Eighteen novel polymorphic and 16 monomorphic microsatellite loci of P. armandii were isolated using Illumina MiSeq technology. The number of alleles per locus ranged from two to five. The expected heterozygosity ranged from 0.061 to 0.609 with an average of 0.384, and the observed heterozygosity ranged from 0.063 to 0.947 with an average of 0.436. Seventeen loci could be successfully transferred to five related Pinus species (P. koraiensis, P. griffithii, P. sibirica, P. pumila, and P. bungeana).Conclusions:These novel microsatellites could potentially be used to investigate the population genetics of P. armandii and related species.
Microbiological Trends and Antimicrobial Resistance in Peritoneal Dialysis-Related Peritonitis, 2005 to 2014
Authors: Zelenitsky Sheryl A. , Howarth Jacy , Lagacé-Wiens Philippe , Sathianathan Christie , Ariano Robert , Davis Christine , Verrelli Mauro 
Published: October 2016

Background Information related to the microbiology of peritonitis is critical to the optimal management of patients receiving peritoneal dialysis (PD). The goal was to characterize the microbiological etiology and antimicrobial susceptibilities of PD-related peritonitis (PDRP) from 2005 to 2014, inclusive. Methods The distribution of organisms in culture-positive PDRP was described for new episodes and relapse infections, and further detailed for monomicrobial and polymicrobial peritonitis. Annual and overall rates of PDRP were also characterized. Antimicrobial susceptibility rates were calculated for the most common and significant organisms. Results We identified 539 episodes of PDRP including 501 new and 38 relapse infections. New episodes of peritonitis were associated with a single organism in 85% of cases, and 44% of those involved staphylococci. Polymicrobial PDRP was more likely to involve gram-negative organisms, observed in 58% versus 24% of monomicrobial infections. Antimicrobial resistance was relatively stable from 2005 to 2014. Methicillin resistance was present in 57% of Staphylococcus epidermidis and 20% of other coagulase-negative staphylococci. Methicillin-resistant Staphylococcus aureus (MRSA) accounted for only 11% of S. aureus peritonitis compared with 2% in our previous study of PDRP from 1991 to 1998. Ciprofloxacin resistance in Escherichia coli increased from 3% in our previous study to 24% in 2005 – 2014. Conclusions This study characterizes important differences in the distribution of organisms in new episodes of PDRP and relapse infections, as well as monomicrobial versus polymicrobial peritonitis. It also shows relatively stable rates of antimicrobial resistance from 2005 to 2014, but some increases compared with our previous study.