bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns of Acute Ischemic Strokes After Carotid Endarterectomy and Therapeutic Implications
Authors: Lareyre Fabien , Raffort Juliette , Weill Caroline , Marsé Claire , Suissa Laurent , Chikande Julien , Hassen-Khodja Réda , Jean-Baptiste Elixène 
Published: August 2017

Aim: Acute ischemic strokes following surgical treatment of carotid stenosis lead to substantial disability and mortality, and vascular mechanisms underlying their development are not fully elucidated. The goal of this study was to analyze the topographic patterns of acute ischemic stroke following carotid endarterectomy (CEA) on diffusion-weighted and perfusion-weighted magnetic resonance imaging (MRI). Material and Methods: Data were retrospectively collected from consecutive patients who underwent CEA and developed postoperative acute ischemic stroke. Based on the MRI data sets, the lesion patterns of acute stoke were characterized. Morphology of the circle of Willis, the 3-D time-of-flight (3D-TOF) of the cerebral arteries, and status of the carotid circulation were also analyzed in order to determine the vascular mechanisms involved in stroke development. Results: Between January 2008 and May 2015, 821 patients were treated surgically for a symptomatic or asymptomatic carotid stenosis at the University Hospital of Nice. Nineteen (2.3%) patients had an acute ischemic stroke after surgery. Among them, 11 (57.9%) patients had a territorial infarction and 8 (42.1%) patients had an internal watershed infarction, cortical watershed infarction, or mixed border zone infarction. According to imaging data sets, embolic mechanism of stroke was reported for 12 (63.2%) patients, hemodynamic mechanism for 2 (10.5%) patients, and mixed mechanism for 5 (26.3%) patients. An asymmetry on 3D-TOF was observed in 60% and 50% of patients with hemodynamic and mixed stroke and in 25% of patients with embolic stroke. The latter 2 patients with embolic stroke underwent successful mechanical thrombectomy using stent-retriever devices. Conclusion: In this cohort, embolic mechanism leading to postoperative stroke was more frequently observed than hemodynamic mechanism. Immediate characterization of the cerebral lesion by postoperative brain MRI is of utmost importance because it may rapidly identify patients eligible for treatments such as mechanical thrombectomy.
Kindlin-1 is a key protein in hyperbaric oxygen therapy for the treatment of neuropathic pain
Authors: Zhao Baisong , He Erning , Pan Yongying , Xu Haiping , Song Xingrong 
Published: August 2017

Background Hyperbaric oxygen therapy is increasingly used in adjuvant therapies to treat neuropathic pain. However, the specific targets of hyperbaric oxygen treatment in neuropathic pain remain unclear. Recently, we found that hyperbaric oxygen therapy produces an antinociceptive response via the kindlin-1/wnt-10a signaling pathway in a chronic pain injury model in rats. Methods The rats received an intraperitoneal injection of AAV-FERMT1 or an adeno-associated virus control vector 20 days before the chronic constriction injury operation. During five consecutive days of hyperbaric oxygen treatment, mechanical withdrawal threshold and thermal withdrawal latency tests were performed. Then, kindlin-1 expression was examined by real-time polymerase chain reaction and Western blot analysis. Meanwhile, the activation of glial cells and the production of TNF-α, IL-1β, and fractalkine were also determined. Results Our findings demonstrated that hyperbaric oxygen therapy inhibited the chronic constriction injury–induced increase in kindlin-1 expression. Furthermore, overexpression of kindlin-1 reversed the antinociceptive effects of hyperbaric oxygen therapy. The observed hyperbaric oxygen–induced reductions in glial cell activation and neuroinflammation, as indicated by the production of TNF-α, IL-1β, and fractalkine, were also prominently diminished in the group with kindlin-1 overexpression. Conclusions Our findings demonstrate that kindlin-1 is a key protein in the action of hyperbaric oxygen therapy in the treatment of neuropathic pain. Indeed, interference with kindlin-1 may be a drug target for reducing the neuroinflammatory responses of the glial population in neuropathic pain.
Source to sink studies between the Shaleitian uplift and surrounding sags: Perspectives on the importance of hinterland relief and catchment area for sediment budget, Western Bohai Bay Basin, China
Authors: Zhu Xiaomin , Li Shunli , Liu Qianghu , Zhang Zili , Xu Changgui , Du Xiaofeng , Li Huiyong , Shi Wenlong 
Published: August 2017

Source-to-sink system analysis, a cutting-edge topic in the field of earth science, encompasses the whole system, from erosion and transportation to sediment accumulation on the earth’s surface, and involves multidisciplinary collaboration. This current analysis, based on high-precision 3D seismic data, well logs, and other drilling data, using quantitative characterization of the source-to-sink elements, documents that Archean-Proterozoic migmatitic granite, Cambrian-Ordovician carbonate and clastic rocks, and Mesozoic volcaniclastic rocks are developed in the Shaleitian uplift from south to north across large relief differences (up to 2300 m). The relief and size of the catchment in the source area were calculated by denudation recovery, time-depth conversion and high-resolution interpretation on seismic data. Three types of sediment-transporting channel system and 20 catchment areas ([Formula: see text]) were documented around the edges of the uplift: paleovalley channels, fault-controlled channels, and fault-transfer channels. The Paleogene sink is dominated by near-source coarse-grained depositional systems, with the lithofacies characteristics of low lake level (sand rich), lake transgressive (mud rich), and uplift period (sand rich). Three types of boundary conditions developed in the region of the Shaleitian uplift: fault-related steep-slopes (single or multiple), fault ramps, and slope patterns. The bedrock composition, catchment area, channel systems, and fault-border patterns in the Shaleitian uplift jointly controlled the types and scales of sedimentary sandbodies. The south Shaleitian tectonic zone functioned as a high-efficiency coupling system in which reservoir sandbodies were developed (extensive length distance, with well-sorted and round-grained sediments, but weak physical properties). The coupling system for the southwest and west Shaleitian tectonic zones is subordinate (near source and sand rich, sand and mud interbedded, and weak physical properties). The coupling system of the northeast Shaleitian tectonic zone is lowest in efficiency (relatively mud rich).
Post-Transplantation Cyclophosphamide-Based Haploidentical Transplantation as Alternative to Matched Sibling or Unrelated Donor Transplantation for Hodgkin Lymphoma: A Registry Study of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation
Authors: Martínez Carmen , Gayoso Jorge , Canals Carmen , Finel Hervé , Peggs Karl , Dominietto Alida , Castagna Luca , Afanasyev Boris , Robinson Stephen , Blaise Didier , Corradini Paolo , Itälä-Remes Maija , Bermúdez Arancha , Forcade Edouard , Russo Domenico , Potter Michael , McQuaker Grant , Yakoub-Agha Ibrahim , Scheid Christof , Bloor Adrian , Montoto Silvia , Dreger Peter , Sureda Anna ,   on behalf of the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation
Published: August 2017

Purpose To compare the outcome of patients with Hodgkin lymphoma who received post-transplantation cyclophosphamide–based haploidentical (HAPLO) allogeneic hematopoietic cell transplantation with the outcome of patients who received conventional HLA-matched sibling donor (SIB) and HLA-matched unrelated donor (MUD). Patients and Methods We retrospectively evaluated 709 adult patients with Hodgkin lymphoma who were registered in the European Society for Blood and Marrow Transplantation database who received HAPLO (n = 98), SIB (n = 338), or MUD (n = 273) transplantation. Results Median follow-up of survivors was 29 months. No differences were observed between groups in the incidence of acute graft-versus-host disease (GVHD). HAPLO was associated with a lower risk of chronic GVHD (26%) compared with MUD (41%; P = .04). Cumulative incidence of nonrelapse mortality at 1 year was 17%, 13%, and 21% in HAPLO, SIB, and MUD, respectively, and corresponding 2-year cumulative incidence of relapse or progression was 39%, 49%, and 32%, respectively. On multivariable analysis, relative to SIB, nonrelapse mortality was similar in HAPLO ( P = .26) and higher in MUD ( P = .003), and risk of relapse was lower in both HAPLO ( P = .047) and MUD ( P < .001). Two-year overall survival and progression-free survival were 67% and 43% for HAPLO, 71% and 38% for SIB, and 62% and 45% for MUD, respectively. There were no significant differences in overall survival or progression-free survival between HAPLO and SIB or MUD. The rate of the composite end point of extensive chronic GVHD and relapse-free survival was significantly better for HAPLO (40%) compared with SIB (28%; P = .049) and similar to MUD (38%; P = .59). Conclusion Post-transplantation cyclophosphamide–based HAPLO transplantation results in similar survival outcomes compared with SIB and MUD, which confirms its suitability when no conventional donor is available. Our results also suggest that HAPLO results in a lower risk of chronic GVHD than MUD transplantation.
Differential Relationships of Anxiety and Autism Symptoms on Social Skills in Young Boys With Fragile X Syndrome
Authors: Reisinger Debra L. , Roberts Jane E. 
Published: August 2017

Abstract
Social skills are critical for academic, social, and psychological success of children with both typical and atypical development. Boys with fragile X syndrome (FXS) are at high risk for social skill impairments, given intellectual impairments and secondary conditions. The present study examines the impact of adaptive behavior, autism symptoms, and anxiety symptoms to social skills at the composite and subdomain level in boys with FXS across age. This cross-sectional study included boys with FXS (3–14 years) contrasted to age-matched typical control boys. Results revealed that social skills are generally within developmental expectations, with adaptive behavior as the primary predictor. Anxiety and autism symptoms emerged as additive risk factors, particularly in the areas of responsibility and self-control.
AGUADAS PARA GANADERÍA BOVINA EN LOS BAJOS SUBMERIDIONALES Y ÁREAS DE INFLUENCIA
Authors: BASAN NICKISCH M. , LAHITTE A. , SOSA D. , SANCHEZ L. , TOSOLINI R. 
Published: August 2017

En el norte de la provincia de Santa Fe, especialmente en la Cuña Boscosa, Bajos Submeridionales y Domo Occidental, se encuentran más de tres millones de cabezas de ganado vacuno, donde uno de los principales condicionantes en la producción es la irregular calidad del agua subterránea para el abrevado de la hacienda. La fl uctuación entre escenarios hidrológicos secos y húmedos repercute directamente en la producción, donde no solo varía el nivel freático del acuífero libre, único aprovechable, sino fundamentalmente la calidad química del agua.El INTA, articulando con el INA, con el Gobierno de Santa Fe y con Centros de Estudio de la UNL, ha concretado unidades demostrativas de investigación y transferencia en campos de productores y unidades experimentales de la Institución, diseñando y proponiendo distintas tecnologías consensuadas con los productores en lo que hace al manejo del agua de lluvia complementada con la subterránea.3 Sistemas de Aguadas se concretaron con diferentes maneras de aprovechar el agua de lluvia con el agua subterránea, sistematizando terrenos para garantizar el acceso y recarga del acuífero libre, con mecanismos de bombeo mediante energía renovable y con sistemas de succión que lo hacen en la parte superfi cial del acuífero, donde todos convergen a un tanque central de mezcla, para garantizar así que todos los animales tomen agua con la misma calidad química, cualquiera sea el lugar de pastaje.Desde el año 2011 se monitorean las variables de interés, donde la premisa es tener controlada la salinidad del agua en el tanque central de mezcla y que sus variaciones a través del año sean graduales, ya que esto maximiza la producción ganadera. Esto se visualiza en cada uno de los 3sistemas y, fundamentalmente en el tanque central de mezcla, donde la cantidad, calidad y oportunidad durante el año evidencian claramente resultados muy positivos en el lugar estudiado.
SUELOS DE BAJA CAPACIDAD PRODUCTIVA EN SANTA FE: MEJORA CON RESIDUOS LÍQUIDOS DE LA INDUSTRIA ALIMENTARIA
Authors: PILATTI M. A. , GHIBERTO P. J. , FELLI O. M. , BADINO O. 
Published: August 2017

Se evaluó el uso de Residuos Líquidos Orgánicos (RLO) de la industria láctea como mejorador de suelos de baja aptitud productiva de Santa Fe (Argentina). En un Natracualf típico sin cultivos, se aplicaron 6.600 kg materia orgánica/ha/año de RLO (2010 a 2014) comparándose con un lotetestigo. Hubo aporte signifi cativo de materia orgánica (MO), nitrógeno (Nt), fósforo (P); calcio (Ca) y azufre (S) al suelo. El Nt y P se lavaron en profundidad debido a que no hubo extracción por cultivos. La adición de Ca originó reducción del contenido de sodio en el perfi l del suelo, así como de potasio (K) y magnesio (Mg). Con RLO cambió negativamente conductividad hidráulica, intervalo hídrico óptimo, arcilla dispersa en agua y densidad de suelo. Se requiere de una mínima remoción del suelo, rotación de cultivos y agregado de Mg para uso agronómico de RLOproponiéndose las propiedades evaluadas para monitorear.
LAS NORMAS JURÍDICAS Y LAS POLÍTICAS PÚBLICAS SOBRE BOSQUES CULTIVADOS EN LAS REGIONES DEL CENTRO Y DE PATAGONIA EN ARGENTINA
Authors: MINAVERRY C. M. 
Published: August 2017

El eje central de este trabajo es analizar el nivel de desarrollo de las normas jurídicas, de las políticas públicas, y de la idoneidad de las autoridades de aplicación sobre bosques cultivados, en las regiones del Centro y de la Patagonia en Argentina. Se trata de una investigación de carácter exploratorio, donde se aplicó el método de la hermenéutica jurídica y los indicadores ambientales PER. Se puede concluir que los niveles de desarrollo normativo de las provincias no son uniformes, y que la mayoría de las normas jurídicas y de las políticas públicas tienden a establecer incentivos económicos para aprovechar el efecto del mercado, sin orientarse hacia una protección integral de los ecosistemas boscosos, y que las autoridades de aplicación en su mayoría no son técnicamente adecuadas para eso.
EVALUACIÓN DE LA CONVENIENCIA DE LOS MACROTÚNELES EN COMPARACIÓN CON MICROTÚNELES PARA EL CULTIVO DE FRUTILLA EN CORONDA.
Authors: PERNUZZI C. , SORDO M. H. , TRAVADELO M. , MAINA M. , ACETTA P. 
Published: August 2017

El uso del macrotúnel forma parte de las últimas tecnologías incorporadas al cultivo de frutilla en la zona de Coronda (Santa Fe) con un alto nivel de aceptación. El objetivo del presente trabajo fue realizar la evaluación de un proyecto de inversión de una hectárea de macrotúneles dedicada al cultivo de frutillas, comparada con la estructura hasta ahora más usada de microtúneles. A partir de lametodología propia de la formulación y evaluación de proyectos a una tasa de corte de 15% y a 10 años, se elaboró el fl ujo de caja siguiendo un criterio incremental, microtúneles vs macrotúneles. El VAN obtenido fue de 1.986.581 $ y una TIR de 107,5%, criterios aceptables para confi rmar la conveniencia de la inversión. Al menos la producción del macrotúnel debería ser de 2.369 kg adicionales respecto al microtúnel para que se justifi que la inversión, siendo el período de repago de 2 años.
Optimization of Conditions for Obtaining Alginate/Olive Oil Capsules for Application in Dairy Industry
Authors: Poirieux Magalie , Kostov Georgi , Denkova Rositsa , Shopska Vesela , Ivanova Mihaela , Balabanova Tatyana , Vlaseva Radka 
Published: August 2017

Abstract
Encapsulation is a process of incorporation of bioactive substances in a specific matrix. It results in increasing and/or maintaining of the biological agent concentration in the food matrix or the fermentation system. The encapsulation process is influenced by various factors. The aim of the present work was to investigate the influence of alginate type and concentration, homogenization rate and the oil phase amount in the preparation of capsules rich in olive oil. It has been found that emulsions obtained with medium viscosity alginate were characterized by better stability. To establish the joint influence of the factors was used screening design experiment, the optimization features selected being temperature, centrifugal and microscopic stability. The optimal levels of the factors were established and they we applied for capsule preparation. The obtained capsules showed maximum stability and possibility to be used in dairy product manufacture.
Effect of Microencapsulation on Survival and Stability of Bifidobacterium bifidum BB01 Exposed to Simulated Gastrointestinal Conditions and in Different Food Matrices
Authors: Chen He , Ma Donglin , Li Yichao , Liu Yu , Wang Ye 
Published: August 2017

Abstract

Bifidobacterium bifidum BB01 was microencapsulated by extrusion method with sodium alginate. This paper aimed to study the survival rate of microencapsulating Bifidobacterium bifidum BB01 in simulated gastrointestinal conditions, resistance to artificial bile salt and stability during storage. Results showed non-microencapsulated Bifidobacterium bifidum BB01 were more susceptible than microencapsulated under simulated gastrointestinal conditions, and microencapsulated Bifidobacterium bifidum BB01 exhibited a lower population reduction than free cells during exposure to simulated gastrointestinal, The enteric test showed that the microorganism cells were released from the monolayer microcapsules, double microcapsules and trilayer completely in 40min. The viable counts of monolayer microcapsules, double layer microcapsules and triple layer microcapsules decreased by nine magnitudes, four magnitude and one magnitude after 2h, respectively. Moreover, in fruit orange, pure milk and nutrition Express, the optimum storage times of free Bifidobacterium bifidum BB01, monolayer microcapsules, double layer microcapsules and triple layer microcapsules were 21 days, 21 days, 28 days and more than 35 days at 4°C, but at room temperature the optimum storage time were 7 days, 14 days, 21 days and more than 28 days, and the viable counts were maintained at 1×106 CFU g−1 or more.
Effect of Duration and Drying Temperature on Characteristics of Dried Tomato (Lycopersicon esculentum L.) Cochoro Variety
Authors: Yusufe Mawardii , Mohammed Ali , Satheesh Neela 
Published: August 2017

Abstract
The objective of the present study was to standardise the duration and temperatures of the conventional oven drying methods for best physical and sensory characteristics of dried tomato. The experiment consisted of two factor factorial design (3*2) with three levels of drying temperature (70°C, 80°C and 90°C) and two levels of drying duration (7 and 8 hours) with three replications. An improved and high yielding variety (Cochoro) of tomato released in 2007 for processing and widely grown in Ziwai (Maki), Ethiopia was used. Prior to drying, individual tomato fruits were washed and sliced into uniform thickness (8mm); then, the slices were placed on to the drying trays in a single layer to facilitate uniform drying in hot air oven set at predetermined temperatures per the respective treatments. Data were collected on different physical and sensory attributes and analysed using SAS software (version 9.2). The results showed that titratable acidity, total soluble solids and water absorption capacity were significantly (p≤0.001) increased due to the interaction of degree of temperature and duration of oven drying. In contrast, pH and water activity decreased as the drying temperature and duration increased. Drying at 70°C for 7 hours produced dried tomatoes with the highest sensorial acceptability and physical attributes while higher temperatures (80, 90°C) and longer duration (9 hours) significantly detract the quality of dried tomato. Hence, it is possible to add value and preserve tomatoes through oven drying at the right temperature and optimum duration.
Detection of Russian olive witches’-broom disease and its insect vector in Northwestern Iran
Authors: Hajizadeh Abasalt , Khakvar Reza , Bashir Nemat Sokhandan , Zirak Leila 
Published: August 2017

Abstract
Recently, Russian olive trees showing witches’-broom and little leaf symptoms have been widely observed in northwestern and central Iran. Polymerase chain reaction (PCR) and nested PCR assays using phytoplasma universal primer pairs confirmed phytoplasma symptomatic infection of trees. Sequence analyses showed that ‘Candidatus Phytoplasma asteris’ was the causal agent of the disease in these regions. However, RFLP results using restriction enzymes HpaII, EcoRI, HinfI and AluI indicated that the collected isolates in these regions are genetically different. In addition, leafhopper Macropsis infuscata was recognized as a possible insect vector of the disease for the first time.
Experimental Study on the Riveted Joints in Glass Fibre Reinforced Plastics (GFRP)
Authors: Bielawski Radosław , Kowalik Michał , Suprynowicz Karol , Rządkowski Witold , Pyrzanowski Paweł 
Published: August 2017

Abstract
The aim of the paper is to validate the use of measurement methods in the study of GFRP joints. A number of tests were carried out by means of a tensile machine. The studies were concerned with rivet connection of composite materials. One performed two series of tests for two different forces and two fibre orientations. Using Finite Element Method (FEM) and Digital Image Correlation (DIC), strain maps in the test samples were defined. The results obtained with both methods were analysed and compared. The destructive force was analysed and, with the use of a strain gauge, the clamping force in a plane parallel to the annihilated sample was estimated. Destruction processes were evaluated and models of destruction were made for this type of materials taking into account their connections, such as riveting.
Cutting Mechanics and Surface Finish for Turning with Differently Shaped CBN Tools
Authors: Żak Krzysztof 
Published: August 2017

Abstract
In this paper, the basic cutting characteristics such as cutting forces, cutting power and its distribution, specific cutting energies were determined taking into account variable tool corner radius ranging from 400 to 1200 µm and constant cutting parameters typical for hard turning of a hardened 41Cr4 alloy steel of 55±1 HRC hardness. Finish turning operations were performed using chamfered CBN tools. Moreover, selected roughness profiles produced for different tool corner radius were compared and appropriate surface roughness parameters were measured. The measured values of Ra and Rz roughness parameters are compared with their theoretical values and relevant material distribution curves and bearing parameters are presented.