bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: SYNTHESIS OF PUMILIOTOXIN C
Authors: HABERMEHL G. , ANDRES H. , MIYAHARA K. , WITKOP B. , DALY J. W. 
Published: March 2016

AbstractDie Kondensation des Esters (I) mit dem Hydrobromid (II) führt unter Cyclisierung zu dem als Racemat anfallenden Ester (III), dessen Hydrolyse und Decarboxylierung das racemische Octahydrochinolin (IV) als Stereoisomerengemisch ergibt.
ChemInform Abstract: CHEMISTRY OF LEUCOMYCINS. XII. APPLICATION OF THE MODIFIED POLONOVSKI REACTION TO LEUCOMYCIN A3 N‐OXIDE
Authors: NAKAGAWA A. , SUZUKI K. , IWASAKI K. , KAJI K. , OMURA S. , JAKUBOWSKI A. , TISHLER M. 
Published: March 2016

AbstractChemistry of Leucomycins.
ChemInform Abstract: A NEW CAPILLARY‐TYPE CLOSED VISCOMETER FOR MOLTEN SALT RESEARCH
Authors: VAN OS N. , KETELAAR J. A. A. 
Published: March 2016

AbstractDas Viskosimeter eignet sich besonders für präzise Messungen mit Flüssigkeiten, die hohe Dampfdrücke haben, stark korrosiv wirken oder mit der Atmosphäre chemische Reaktionen eingehen.
ChemInform Abstract: COMPETITION BETWEEN AMMONIA AND THE NITRITE ION AS LEAVING GROUPS IN COBALT(III) COMPLEXES. 3. HYDROLYSIS OF NITROAMMINECOBALT(III) COMPLEXES
Authors: BALT S. , DEKKER C. 
Published: March 2016

AbstractDie Kinetik der Aquotisierung der Komplexe (I)‐(V) in schwach alkalischen ammoniakalischen Lösungen wird mit einer spektrophotometrischen Methode untersucht.
ChemInform Abstract: ANION CRYPTATES‐ HIGHLY STABLE AND SELECTIVE MACROTRICYCLIC ANION INCLUSION COMPLEXES
Authors: GRAF E. , LEHN J.‐M. 
Published: March 2016

AbstractDer bereits beschriebene makrotricyclische Ligand (Ia) bildet, wie NMR‐spektroskopisch gezeigt wird, mit F‐, Cl‐ und Br‐, nicht jedoch mit J‐ oder mehratomigen Anionen wie Nitrat, Einschlußverbindungen bei gleichzeitiger Tetraprotonierung.
ChemInform Abstract: NITROSYLATION OF PHENETOLE
Authors: KUZNETSOVA S. S. , KOROVKINA T. YU. , SHARKOVA T. B. 
Published: March 2016

AbstractBei der Umsetzung von Phenetol (I) mit Natriumnitrit in 99,9%iger Schwefelsäure erhält man in 55% Ausbeute p‐Nitroso‐phenetol (II).
ChemInform Abstract: A NEW SYNTHESIS OF DL‐MUSCONE
Authors: BAUMANN M. , HOFFMANN W. , MUELLER N. 
Published: March 2016

AbstractAus Cyclododecanon (I) entsteht mit Butinol in Gegenwart von KOH das Addukt (II), das mit Schwefelsäure/Essigsäure zu (III) umgelagert und kondensiert wird.
ChemInform Abstract: FORMYLATION OF DERIVATIVES OF 2‐PHENYL‐ AND 3‐PHENYL‐5‐HYDROXYBENZOFURANS
Authors: GRINEV A. N. , ZOTOVA S. A. 
Published: March 2016

AbstractDie Vilsmeier‐Formylierung des 3‐Phenylbenzofurans (I) führt zu dem Aldehyd (II), der über das Oxim in ein Nitril und die entpsrechende Carbonsäure umgewandelt wird.
ChemInform Abstract: TETRAHYDRO‐ AND OCTAHYDROPYRIDO(1,2‐A)PYRIMIDIN‐4‐ONES
Authors: YALE H. L. , SPITZMILLER E. R. 
Published: March 2016

AbstractDie Hydrierung der Pyridopyrimidinone (I) zu (II) und (III) über Ra‐Ni wird untersucht.
ChemInform Abstract: STUDIES ON THE CHEMISTRY OF HETEROCYCLES. LVIII. SYNTHESIS OF DERIVATIVES OF 1,1‐DIOXO‐2H‐1,2,4‐BENZOTHIADIAZINE‐3‐CARBOXYLIC ACID FROM 2‐SULFAMOYLOXANILIC ACID ESTERS
Authors: PETYUNIN P. A. , PETYUNIN G. P. , BONDARCHUK I. I. , KOLESNIKOVA T. A. 
Published: March 2016

AbstractDie Sulfanilamide (I) reagieren mit den Alkoxalylchloriden (II) zu Oxanilsäureestern (III), die mit Natriummethylat zu Benzothiadiazinoxiden (IV) cyclisieren.
ChemInform Abstract: AXIAL AND EQUATORIAL PHOSPHORUS‐OXYGEN BASICITY IN A SIX‐MEMBERED RING PHOSPHATE ANION‐ EFFECT OF THE COUNTERCATION
Authors: HONG A. P. , LEE J.‐B. , VERKADE J. G. 
Published: March 2016

AbstractUntersuchungen der Methylierung der aus der Säure dargestellten Salze (I) des starren sechsgliedrigen Ringphosphatanions zeigen, daß die nichtkomplexierenden Na‐, Cs‐ und Tetramethylammonium‐Salze (Ia) bevorzugt das in axialer Position veresterte Isomere (IIIb) bilden.
ChemInform Abstract: PHOSPHORUS‐CONTAINING PRODUCTS FROM THE REACTION OF PROPARGYL ALCOHOLS WITH PHOSPHORUS TRIHALIDES. 4. ALKYL SUBSTITUENT EFFECTS ON OXAPHOSPHOLENE FORMATION
Authors: MACOMBER R. S. , KENNEDY E. R. 
Published: March 2016

AbstractAus den Propargylalkoholen (I) erhält man mit Phosphortrichlorid die Chlorphosphite (II), die bei Ausschluß bzw. rascher Entfernung des gebildeten Chlorwasserstoffs zu den Chlor‐allenen (III) sowie den Cyclisierungsprodukten (IV) führen.
ChemInform Abstract: EXISTENCE OF TWO ISOMERIC FORMS OF CHROMIUM(II) COMPLEXES WITH SATURATED MACROCYCLIC LIGANDS
Authors: DEI A. , MANI F. 
Published: March 2016

AbstractDurch stöchiometrische Umsetzung von Cr(II)‐halogeniden mit den N4‐Liganden in DMFA entstehen die luft‐ und feuchtigkeitsempfindlichen Cr(II)‐Komplexe (I).
ChemInform Abstract: CATIONIC CARBONYL AND RELATED COMPLEXES OF PENTACHLOROPHENYLNICKEL(II)
Authors: WADA M. , OGURO K. 
Published: March 2016

AbstractDer Chloridligand in den trans‐Komplexen (I) ist labil und reagiert mit Ag‐perchlorat in Benzol zu den Produkten (II).
ChemInform Abstract: STEREOSPECIFIC TOTAL SYNTHESIS OF (+)‐ε‐ AND (‐)‐Γ2‐CADINENE
Authors: BURK L. A. , SOFFER M. D. 
Published: March 2016

Abstract(+)‐e‐Cadinen (IV) und (‐)‐′y2‐Cadinen (VI) werden aus dem Enolätherketon (I) über das Methylenketon (III) synthetisiert.
Stroke and Systemic Embolism After Successful Ablation of Typical Atrial Flutter
Authors: Expósito Víctor , Rodríguez‐Entem Felipe , González‐Enríquez Susana , Veiga Gabriela , Olavarri Iván , Olalla Juan J. 
Published: March 2016

ABSTRACTBackgroundFollowing successful cavotricuspid isthmus (CTI) ablation during typical atrial flutter (AFL), anticoagulation therapy is usually withdrawn. However, potential subsequent atrial fibrillation (AF) in these patients may increase embolic risk in the long term. Embolic rates in this setting have not been clearly established. Our aim was to determine the incidence of stroke/systemic embolism following radiofrequency ablation of AFL, particularly in those without a prior history of AF.HypothesisAfter succesful AFL ablation, patients may suffer embolic complications in the long‐term follow‐up, mainly due to asymptomatic AF episodes.MethodsWe conducted a retrospective analysis of all patients who underwent CTI ablation due to AFL in our center between 2006 and 2009.ResultsDuring the study period, 188 patients (mean age, 62.9 ± 8.6 years) underwent CTI ablation; 120 without prior AF were included in the study. At the end of the follow‐up period (mean, 5.0 ± 2.4 years), 56.7% of patients (68/120) remained in sinus rhythm, 7/120 experienced a recurrence of AFL, and 45/120 (38%) developed AF. Ischemic stroke occurred in 11 patients and systemic embolism in 1. Of these patients, 5 had documented AF following AFL ablation. In the remaining 7 cases, previously undiagnosed AF was subsequently diagnosed at the time of stroke/embolism.ConclusionsPatients with AFL who undergo successful ablation are by no means free from embolic complications during long‐term follow‐up, mainly due to a high rate of AF development. Given the difficulties in detecting AF and the uncertainty about the temporal relation of AF and stroke, oral anticoagulation may need to be continued in those patients with underlying stroke risk factors.
Accuracy of advanced cancer patients' life expectancy estimates: The role of race and source of life expectancy information
Authors: Trevino Kelly M. , Zhang Baohui , Shen Megan J. , Prigerson Holly G. 
Published: March 2016

BACKGROUNDThe objective of this study was to examine the source of advanced cancer patients' information about their prognosis and determine whether this source of information could explain racial disparities in the accuracy of patients' life expectancy estimates (LEEs).METHODSCoping With Cancer was a prospective, longitudinal, multisite study of terminally ill cancer patients followed until death. In structured interviews, patients reported their LEEs and the sources of these estimates (ie, medical providers, personal beliefs, religious beliefs, and other). The accuracy of LEEs was calculated through a comparison of patients' self‐reported LEEs with their actual survival.RESULTSThe sample for this analysis included 229 patients: 31 black patients and 198 white patients. Only 39.30% of the patients estimated their life expectancy within 12 months of their actual survival. Black patients were more likely to have an inaccurate LEE than white patients. A minority of the sample (18.3%) reported that a medical provider was the source of their LEEs; none of the black patients (0%) based their LEEs on a medical provider. Black race remained a significant predictor of an inaccurate LEE, even after the analysis had been controlled for sociodemographic characteristics and the source of LEEs.CONCLUSIONSThe majority of advanced cancer patients have an inaccurate understanding of their life expectancy. Black patients with advanced cancer are more likely to have an inaccurate LEE than white patients. Medical providers are not the source of information for LEEs for most advanced cancer patients and especially for black patients. The source of LEEs does not explain racial differences in LEE accuracy. Additional research into the mechanisms underlying racial differences in prognostic understanding is needed. Cancer 2016;122:1905–12. © 2016 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
A Genuine Jahn–Teller System with Compressed Geometry and Quantum Effects Originating from Zero‐Point Motion
Authors: Aramburu José Antonio , García‐Fernández Pablo , García‐Lastra Juan María , Moreno Miguel 
Published: March 2016

AbstractFirst‐principle calculations together with analysis of the experimental data found for 3d9 and 3d7 ions in cubic oxides proved that the center found in irradiated CaO:Ni2+ corresponds to Ni+ under a static Jahn–Teller effect displaying a compressed equilibrium geometry. It was also shown that the anomalous positive g∥ shift (g∥−g0=0.065) measured at T=20 K obeys the superposition of the |3 z2−r2⟩ and |x2−y2⟩ states driven by quantum effects associated with the zero‐point motion, a mechanism first put forward by O'Brien for static Jahn–Teller systems and later extended by Ham to the dynamic Jahn–Teller case. To our knowledge, this is the first genuine Jahn–Teller system (i.e. in which exact degeneracy exists at the high‐symmetry configuration) exhibiting a compressed equilibrium geometry for which large quantum effects allow experimental observation of the effect predicted by O'Brien. Analysis of the calculated energy barriers for different Jahn–Teller systems allowed us to explain the origin of the compressed geometry observed for CaO:Ni+.
Populations of aspen (Populus tremuloides Michx.) with different evolutionary histories differ in their climate occupancy
Authors: Greer Burke T. , Still Christopher , Howe Glenn T. , Tague Christina , Roberts Dar A. 
Published: March 2016

AbstractQuaking aspens (Populus tremuloides Michx.) are found in diverse habitats throughout North America. While the biogeography of aspens' distribution has been documented, the drivers of the phenotypic diversity of aspen are still being explored. In our study, we examined differences in climate between northern and southwestern populations of aspen, finding large‐scale differences between the populations. Our results suggest that northern and southwestern populations live in distinct climates and support the inclusion of genetic and phenotypic data with species distribution modeling for predicting aspens' distribution.
Hydrogen Photoevolution from a Green‐Absorbing Iridium(III)–Cobalt­(III) Dyad
Authors: Jacques Alexandre , Schott Olivier , Robeyns Koen , Hanan Garry S. , Elias Benjamin 
Published: March 2016

AbstractA bis‐cyclometaling ligand afforded a novel IrIII–CoIII dinuclear complex with vectorial electron transfer that evolved hydrogen gas upon yellow‐light irradiation. The supramolecular photosystem provided increased stability during photocatalysis with respect to that of classic bidentate systems.
Electrochemical Synthesis of β‐Cyclodextrin Functionalized Silver Nanoparticles and Reduced Graphene Oxide Composite for the Determination of Hydrazine
Authors: Devasenathipathy Rajkumar , Tsai Shin‐Hung , Chen Shen‐Ming , Karuppiah Chelladurai , Karthik Raj , Wang Sea‐Fue 
Published: March 2016

Abstractβ‐cyclodextrin (β‐CD) functionalized silver nanoparticles (AgNPs) and reduced graphene oxide (RGO) via one step electrochemical potentiodyanamic method has been prepared. Scanning electron microscopy, Energy‐Dispersive X‐ray spectroscopy, electrochemical impedance spectroscopy and cyclic voltammetry were used to study the role of β‐CD on preparation of AgNPs and RGO. RGO/β‐CD/AgNPs modified GCE showed good electrochemical activity towards electro‐oxidation of hydrazine in terms of decreasing the over potential and increasing the peak current. The kinetic parameters such as electron transfer coefficient (α) and diffusion coefficient (Do) of the modified electrode towards hydrazine were determined to be 0.66 and 0.97×10−6 cm2 s−1, respectively. The LOD of our sensor was many folds lower than that of recommended concentration of hydrazine in drinking water by United States Environmental Protection Agency and World Health Organization. The sensor exhibited a wide linear range from 0.08 to 1110 µM and a very low detection limit (LOD) of 1.4 nM. In addition, the sensor selectively determined hydrazine even in the presence of common interferents.
Continuous‐Flow Preparation of a Magnetite@Carbon Composite for High‐Performance Lithium‐Ion Battery Electrodes
Authors: Liu Yunfang , Ren Sen , Chi Weidong , Huang Qigu , Yu Changyuan 
Published: March 2016

AbstractA magnetite@carbon (Fe3O4@C) composite is continuously synthesized by coupling microfluidic synthesis and spraying pyrolysis. The Fe3O4 nanoparticles have an average size of 9.5 nm with narrow size distribution. The porous Fe3O4@C composite used as lithium‐ion battery electrode shows a high reversible capacity (≈710 mAh g−1 at 200 mA g−1) with excellent cycling stability.
The Influence of Personality Traits on Emotion Expression in Bulimic Spectrum Disorders: A Pilot Study
Authors: Giner‐Bartolomé Cristina , Steward Trevor , Wolz Ines , Jiménez‐Murcia Susana , Granero Roser , Tárrega Salomé , Fernández‐Formoso José Antonio , Soriano‐Mas Carles , Menchón José M. , Fernández‐Aranda Fernando 
Published: March 2016

AbstractFacial expressions are critical in forming social bonds and in signalling one's emotional state to others. In eating disorder patients, impairments in facial emotion recognition have been associated with eating psychopathology severity. Little research however has been carried out on how bulimic spectrum disorder (BSD) patients spontaneously express emotions. Our aim was to investigate emotion expression in BSD patients and to explore the influence of personality traits. Our study comprised 28 BSD women and 15 healthy controls. Facial expressions were recorded while participants played a serious video game. Expressions of anger and joy were used as outcome measures. Overall, BSD participants displayed less facial expressiveness than controls. Among BSD women, expressions of joy were positively associated with reward dependence, novelty seeking and self‐directedness, whereas expressions of anger were associated with lower self‐directedness. Our findings suggest that specific personality traits are associated with altered emotion facial expression in patients with BSD. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.
Poor prognosis in human papillomavirus–positive oropharyngeal squamous cell carcinomas that overexpress hypoxia inducible factor‐1α
Authors: Swartz Justin Egidius , Pothen Ajit Joe , van Kempen Pauline Maria Wilhelmina , Stegeman Inge , Formsma Fleurieke Karlijn , Cann Ellen Maria Van , Willems Stefan Martin , Grolman Wilko 
Published: March 2016

AbstractBackgroundHypoxia induces stabilization of the transcription factor HIF‐1alpha (HIF‐1α), associated with (chemo‐)radiotherapy resistance in oropharyngeal squamous cell carcinoma (SCC). We investigated the effect of HIF‐1α expression on survival in relation to human papillomavirus (HPV) status in oropharyngeal SCC.MethodsWe conducted an immunohistochemical analysis of HIF‐1α protein expression and downstream targets carbonic anhydrase‐IX (CA‐IX) and glucose transporter‐1 (GLUT‐1) in 274 patients with oropharyngeal SCC. Overall survival (OS) was analyzed in total and stratified for HPV status and treatment.ResultsIn HPV‐positive tumors (n = 44), HIF‐1α overexpression predicted worse OS (hazard ratio [HR] = 6.23; p = .012), whereas TNM classification or treatment modality did not. In HPV‐negative tumors (n = 218), advanced T and N classification and HIF‐1α overexpression all independently predicted worse OS. However, the effect of HIF‐1α overexpression on OS was lower in HPV‐negative (HR = 1.50; p = .024) than in HPV‐positive tumors.ConclusionHIF‐1α overexpression is associated with worse OS and characterized a subgroup of patients with HPV‐positive oropharyngeal SCC with poor prognosis. Possibly, patients with HIF‐1α overexpressing HPV‐positive tumors should not be eligible for treatment dose deescalation. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1338–1346, 2016
The Effectiveness of Foreign Aid to Women's Equality Organisations in the MENA
Authors: Baliamoune‐Lutz Mina 
Published: March 2016

AbstractWe use panel data (covering the period 2002–2010) from 13 MENA countries and control for several relevant variables, including secondary school enrolments, adult fertility rates, autocracy, and official development assistance targeting family planning and reproductive health. The results suggest that official development assistance to women' equality organisations and institutions is effective in increasing women's political empowerment. We find that autocracy exerts a negative influence on women's political empowerment while higher adolescent fertility rates are associated with smaller proportion of seats held by women in national parliaments. We comment on the policy implications of the main findings. © 2016 UNU‐WIDER. Journal of International Development published by John Wiley & Sons, Ltd.
Measurement of arteriolar blood volume in brain tumors using MRI without exogenous contrast agent administration at 7T
Authors: Wu Yuankui , Agarwal Shruti , Jones Craig K. , Webb Andrew G. , van Zijl Peter C.M. , Hua Jun , Pillai Jay J. 
Published: March 2016

PurposeArteriolar cerebral‐blood‐volume (CBVa) is an important perfusion parameter that can be measured using inflow‐based vascular‐space‐occupancy (iVASO) MRI without exogenous contrast agent administration. The purpose of this study is to assess the potential diagnostic value of CBVa in brain tumor patients by comparing it with total‐CBV (including arterial, capillary and venous vessels) measured by dynamic‐susceptibility‐contrast (DSC) MRI.Materials and MethodsTwelve brain tumor patients were scanned using iVASO (on 7T as part of a research project) and DSC (on 3T as part of routine clinical protocols) MRI. Region‐of‐interest analysis was performed to compare the resulting perfusion measures between tumoral and contralateral regions, and to evaluate their associations with tumor grades.ResultsCBVa measured by iVASO MRI significantly correlated with WHO grade (ρ = 0.37, P = 0.04). Total‐CBV measured by DSC MRI showed a trend of correlation with WHO grade (ρ = 0.28, P = 0.5). The signal‐to‐noise ratio was comparable (P > 0.1) between the two methods, while the contrast‐to‐noise ratio between tumoral and contralateral regions was higher in iVASO‐CBVa than DSC‐CBV in WHO II/III patients (P < 0.05) but comparable in WHO IV patients (P > 0.1). A trend of positive correlation between DSC‐CBV and iVASO‐CBVa was observed (R2 = 0.28, P = 0.07).ConclusionIn this initial patient study, CBVa demonstrated a stronger correlation with WHO grade than total‐CBV. Further investigation with a larger cohort is warranted to validate whether CBVa can be a better classifier than total‐CBV for the stratification of brain tumors, and whether iVASO MRI can be a useful alternative method for the assessment of tumor perfusion, especially when exogenous contrast agent administration is difficult in certain patient populations. J. Magn. Reson. Imaging 2016;44:1244–1255.
A multilevel perspective of interpersonal trust: Individual, dyadic, and cross‐level predictors of performance
Authors: Gupta Naina , Ho Violet , Pollack Jeffrey M. , Lai Lei 
Published: March 2016

SummaryWhile it is generally known that interpersonal trust facilitates individual functioning, few studies have examined the role of specific features of the interpersonal trust network — individual, dyadic, third‐party, and network‐level features — on individual performance. We adopt a multilevel perspective of interpersonal trust to examine how individuals' performance is not only predicted by their individual‐level centrality in the interpersonal trust network but also moderated, at the network level, by the overall centralized nature of that network. Further, we examine whether mutual trust relationships at the dyadic level, as well as shared trust ties to common third parties, can predict individuals' performance. We test our hypotheses with 206 members in 15 professional networking groups and find that interpersonal trust operates at multiple levels to predict members' performance in terms of generating income from business referrals. These findings provide theoretical and practical implications on how interpersonal trust relationships operate and can be managed for performance gains. Copyright © 2016 John Wiley & Sons, Ltd.
Safety assessment of selected medicinal food plants used in Ayurveda through CYP450 enzyme inhibition study
Authors: Kar Amit , Pandit Subrata , Mukherjee Kakali , Bahadur Shiv , Mukherjee Pulok K 
Published: March 2016

AbstractBACKGROUNDAndrographis paniculata, Bacopa monnieri and Centella asiatica are mentioned in Ayurveda for the management of neurodegenerative disorders. These plants and their phytomolecules, such as andrographolide, bacoside A and asiaticoside, were studied for their inhibition potential on pooled CYP450 as well as human CYP3A4, CYP2D6, CYP2C9 and CYP1A2 by CYP‐CO complex assay and fluorogenic assay respectively followed by IC50 determination. Quantification of bioactive compounds present in the extracts was done by RP‐HPLC. Heavy metal content in the selected medicinal plants was determined by atomic absorption spectroscopy.RESULTCYP‐CO complex assay indicated significantly less inhibition potential than standard inhibitor (P < 0.05 and above). A. paniculata showed highest inhibitory activity against CYP3A4 and CYP2D6 (IC50 = 63.06 ± 1.35 µg mL−1; 88.80 ± 3.32 µg mL−1), whereas C. asiatica and B. monnieri showed least inhibitory activity against CYP1A2 (IC50 = 288.83 ± 1.61 µg mL−1) and CYP2C9 (184.68 ± 3.79 µg mL−1), respectively. In all cases the extract showed higher inhibition than the single bioactive compounds. The heavy metals content in the plant extracts were within the permissible limits.CONCLUSIONThe findings suggested that selected food plants and bioactive compounds contributed negligible interaction potential with CYP isozymes and may not possess any harmful effect with regard to their therapeutic application. © 2016 Society of Chemical Industry