bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emphasis Framing and the Role of Perceived Knowledge: A Survey Experiment
Authors: Bullock Justin B. , Vedlitz Arnold 
Published: March 2017

AbstractThe relationship between emphasis framing and public opinion has received considerable attention in political science, psychology, and mass communication studies. However, what moderating role perceived knowledge plays in influencing emphasis framing remains unsettled. We explore this relationship using a survey‐experiment embedded within a large‐N, nationally representative survey that allows us to test two specific hypotheses. First, we empirically test whether an emphasis frame influences policy support. Second, we test the moderating effect of perceived knowledge. We test the emphasis framing effects of the name given to a “hot‐button” political issue, while controlling for other survey treatments. Furthermore, we evaluate the degree to which perceived knowledge of the issue moderates the relationship between the emphasis frame and support for hydraulic fracturing. We find support both for the role emphasis framing plays and for perceived knowledge as a moderator.
Stratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers
Authors: Knudsen Erik S. , Vail Paris , Balaji Uthra , Ngo Hoai , Botros Ihab W. , Makarov Vladimir , Riaz Nadeem , Balachandran Vinod , Leach Steven , Thompson Debrah M. , Chan Timothy A. , Witkiewicz Agnieszka K. 
Published: March 2017

Abstract
Purpose: Pancreatic ductal adenocarcinoma (PDAC) is associated with an immunosuppressive milieu that supports immune system evasion and disease progression. Here, we interrogated genetic, stromal, and immunologic features of PDAC to delineate impact on prognosis and means to more effectively employ immunotherapy.
Experimental Design: A cohort of 109 PDAC cases annotated for overall survival was utilized as a primary discovery cohort. Gene expression analysis defined immunologic subtypes of PDAC that were confirmed in the Cancer Genome Atlas dataset. Stromal and metabolic characteristics of PDAC cases were evaluated by histologic analysis and immunostaining. Enumeration of lymphocytes, as well as staining for CD8, FOXP3, CD68, CD163, PDL1, and CTLA4 characterized immune infiltrate. Neoantigens were determined by analysis of whole-exome sequencing data. Random-forest clustering was employed to define multimarker subtypes, with univariate and multivariate analyses interrogating prognostic significance.
Results: PDAC cases exhibited distinct stromal phenotypes that were associated with prognosis, glycolytic and hypoxic biomarkers, and immune infiltrate composition. Immune infiltrate was diverse among PDAC cases and enrichment for M2 macrophages and select immune checkpoints regulators were specifically associated with survival. Composite analysis with neoantigen burden, immunologic, and stromal features defined novel subtypes of PDAC that could have bearing on sensitivity to immunologic therapy approaches. In addition, a subtype with low levels of neoantigens and minimal lymphocyte infiltrate was associated with improved overall survival.
Conclusions: The mutational burden of PDAC is associated with distinct immunosuppressive mechanisms that are conditioned by the tumor stromal environment. The defined subtypes have significance for utilizing immunotherapy in the treatment of PDAC. Clin Cancer Res; 23(15); 4429–40. ©2017 AACR.
Hang Height of Enteral Nutrition Influences the Delivery of Enteral Nutrition
Authors: Walker Renee , Probstfeld Lauren , Tucker Anne 
Published: March 2017

AbstractPurpose: Adequate enteral nutrition (EN) delivery to critically ill patients is difficult to achieve. Given the large number of unpreventable influences affecting adequate caloric intake, further research on preventable influences of adequate EN administration is warranted. The purpose of this study was to evaluate whether hang height of EN formula, formula viscosity, or flow rate influences pump accuracy and formula delivery. Methods: Formulas of varying viscosities (1.0, 1.5, and 2.0 kcal/mL) were infused at different hang heights (0, 6, 12, and 18 inches) and rates (20, 40, and 80 mL/h). The mean percent difference and the bias between the programmed volume, volume reported, and volume delivered were calculated for the different hang heights, formula compositions, and infusion rates studied. Results: For all prespecified hang heights and infusion rates, the volume delivered was less than the programmed volume and volume reported; the mean percent difference increased as the hang height decreased. The volume was overestimated for both the programmed volume (14.4% ± 5.5%) and volume reported (12.9% ± 6.7%) compared with volume delivered. The overestimation bias was significantly influenced by differences in hang height as well as type of formula (P < .0001, each) but not by rate of delivery (P = .4633 for programmed volume and .8411 for volume reported). Conclusions: Measures should be taken in clinical practice to ensure adequate hang height of EN. Appropriate hang height of EN may result in more accurate delivery of nutrition provisions to the critically ill patient and subsequently reduce complications related to underfeeding.
Minimising compassion fatigue in obstetrics/gynaecology doctors: exploring an intervention for an occupational hazard
Authors: Allen Rosemary , Watt Felice , Jansen Brendan , Coghlan Edwina , Nathan Elizabeth A 
Published: March 2017

Aim: To explore the indicators of occupational stress in a group of obstetrics and gynaecology doctors and to investigate the impact of work-focused discussion groups over a 6 month period. Methods: The ProQOL questionnaire was used to measure the efficacy of monthly psychiatrist-led Balint style discussion groups on minimising Compassion Fatigue (consisting of Secondary Traumatic Stress and Burnout). The 25 doctors were given the given the ProQOL questionnaire to complete: (a) at the initiation of the intervention in July 2015, (b) in October 2015, and (c) in December 2015. Results: Significantly decreased levels of Secondary Traumatic Stress ( p=0.008), Burnout ( p=0.010), as well as significantly increased rates of Compassion Satisfaction ( p=0.035) were recorded. Participants requested that the groups be continued. Conclusions: Psychiatrist-led work focused discussion groups were associated with improved rates of Secondary Traumatic Stress, Burnout, and Compassion Satisfaction in this sample group.
Oxytocin Augmentation in Spontaneously Laboring, Nulliparous Women: Multilevel Assessment of Maternal BMI and Oxytocin Dose
Authors: Carlson Nicole S. , Corwin Elizabeth J. , Lowe Nancy K. 
Published: March 2017

Background:Synthetic oxytocin, the primary tool for labor augmentation, is less effective among obese women, leading to more unplanned cesarean deliveries for slow labor progress. It is not known if obese women require higher doses of oxytocin due to maternal, fetal, or labor factors related to maternal obesity.Objectives:This study had two main objectives: (1) examine the influence of maternal body mass index (BMI) on hourly doses of oxytocin from augmentation initiation until vaginal delivery in obese women; and (2) examine the influence of other maternal, fetal, and labor factors on hourly doses of oxytocin in obese women.Study Design:Longitudinal study of a cohort ( N = 136) of healthy, nulliparous, spontaneously laboring obese women (BMI ≥ 30 kg/m2) who received oxytocin augmentation and achieved vaginal delivery. We performed iterative multilevel analyses to examine the influence of maternal BMI and other factors on hourly oxytocin doses.Results:Maternal BMI explained 16.56% (95% confidence interval [CI] = [13.7, 20.04], p < .001) of the variance in hourly oxytocin doses received in a multilevel model controlling for influence of maternal, fetal, and labor characteristics. Maternal age, gestational age, status of amniotic membranes at hospital admission, and admission cervical dilation examination were not significant; however, neonatal birthweight and cervical dilation at oxytocin initiation were significant predictors of hourly oxytocin dose in these women ( p < .001).Conclusions:Even when parturition preparation has progressed adequately for spontaneous labor initiation, there still may be some obesity-related blunting of myometrial contractility and response to oxytocin used for augmentation.
Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model
Authors: Dalela Deepansh , Santiago-Jiménez María , Yousefi Kasra , Karnes R. Jeffrey , Ross Ashley E. , Den Robert B. , Freedland Stephen J. , Schaeffer Edward M. , Dicker Adam P. , Menon Mani , Briganti Alberto , Davicioni Elai , Abdollah Firas 
Published: March 2017

Purpose Despite documented oncologic benefit, use of postoperative adjuvant radiotherapy (aRT) in patients with prostate cancer is still limited in the United States. We aimed to develop and internally validate a risk-stratification tool incorporating the Decipher score, along with routinely available clinicopathologic features, to identify patients who would benefit the most from aRT. Patient and Methods Our cohort included 512 patients with prostate cancer treated with radical prostatectomy at one of four US academic centers between 1990 and 2010. All patients had ≥ pT3a disease, positive surgical margins, and/or pathologic lymph node invasion. Multivariable Cox regression analysis tested the relationship between available predictors (including Decipher score) and clinical recurrence (CR), which were then used to develop a novel risk-stratification tool. Our study adhered to the Transparent Reporting of a Multivariable Prediction Model for Individual Prognosis or Diagnosis guidelines for development of prognostic models. Results Overall, 21.9% of patients received aRT. Median follow-up in censored patients was 8.3 years. The 10-year CR rate was 4.9% vs. 17.4% in patients treated with aRT versus initial observation ( P < .001). Pathologic T3b/T4 stage, Gleason score 8-10, lymph node invasion, and Decipher score > 0.6 were independent predictors of CR (all P < .01). The cumulative number of risk factors was 0, 1, 2, and 3 to 4 in 46.5%, 28.9%, 17.2%, and 7.4% of patients, respectively. aRT was associated with decreased CR rate in patients with two or more risk factors (10-year CR rate 10.1% in aRT v 42.1% in initial observation; P = .012), but not in those with fewer than two risk factors ( P = .18). Conclusion Using the new model to indicate aRT might reduce overtreatment, decrease unnecessary adverse effects, and reduce risk of CR in the subset of patients (approximately 25% of all patients with aggressive pathologic disease in our cohort) who benefit from this therapy.
Nuclear α-catenin mediates the DNA damage response via β-catenin and nuclear actin
Authors: Serebryannyy Leonid A. , Yemelyanov Alex , Gottardi Cara J. , de Lanerolle Primal 
Published: March 2017

ABSTRACT
α-Catenin is an F-actin-binding protein widely recognized for its role in cell–cell adhesion. However, a growing body of literature indicates that α-catenin is also a nuclear protein. In this study, we show that α-catenin is able to modulate the sensitivity of cells to DNA damage and toxicity. Furthermore, nuclear α-catenin is actively recruited to sites of DNA damage. This recruitment occurs in a β-catenin-dependent manner and requires nuclear actin polymerization. These findings provide mechanistic insight into the WNT-mediated regulation of the DNA damage response and suggest a novel role for the α-catenin–β-catenin complex in the nucleus.
A hidrelétrica de Nova Ponte-MG, Brasil, e a problemática dos deslocamentos compulsórios
Authors: Silva Vicente De Paulo da 
Published: March 2017

Neste trabalho buscou-se apresentar a problemática dos deslocamentos compulsórios como efeitos da opção por grandes empreendimentos. O foco foi a cidade de Nova Ponte, no estado de Minas Gerais, Brasil, onde a construção de uma Usina Hidrelétrica promoveu a submersão de toda a área urbana da cidade e, consequentemente, a construção de uma cidade nova que também se chamou Nova Ponte. O objetivo é mostrar que reconstruir uma cidade não deve ser entendido apenas do ponto de vista da reconstrução de prédios e ruas mas, acima de tudo, da reconstrução da vidacotidiana que vai ganhando densidade. https://doi.org/10.14195/1647-7723_24_8
Towards the Automatic Estimation of Time Delays of Gravitational Lenses
Authors: Hirv A. , Olspert N. , Pelt J. 
Published: March 2017

Abstract
Estimation of time delays from a noisy and gapped data is one of the simplest data analysis problems in astronomy by its formulation. But as history of real experiments show, the work with observed datasets can be quite complex and evolved. By analyzing in detail previous attempts to build delay estimation algorithms we try to develop an automatic and robust procedure to perform the task. To evaluate and compare different variants of the algorithms we use real observed datasets which have been objects of past controversies. In this way we hope to select the methods and procedures which have highest probability to succeed in complex situations. As a result of our investigations, we propose an estimation procedure which can be used as a method of choice in large photometric experiments. We cannot claim that the proposed methodology works with any reasonably well sampled input dataset. However we hope that the steps taken are in correct direction and the developed software will be useful for observational astronomers.
Grigori Kuzmin and Stellar Dynamics
Authors: Zeeuw P. Tim de , Ven Glenn van de 
Published: March 2017

Abstract
Grigori Kuzmin was a very gifted dynamicist and one of the towering figures in the distinguished history of the Tartu Observatory. He obtained a number of important results in relative isolation which were later rediscovered in the West. This work laid the foundation for further advances in the theory of stellar systems in dynamical equilibrium, thereby substantially increasing our understanding of galaxy dynamics.
Some Properties of Galaxy Structures
Authors: Flin Piotr , Biernacka Monika , Godłowski Włodzimierz , Panko Elena , Piwowarska Paulina 
Published: March 2017

Abstract
We analysed some properties of galaxies structures based on the PF catalog of galaxy structures (Panko & Flin 2006) and the Tully NBG catalog (Tully 1988). At first, we analyzed the orientation of galaxies in the 247 optically selected rich Abell clusters, having at least 100 members. The distribution of the position angles of galaxies as well as of two angles describing spatial orientation of the galaxy planes were tested for isotropy, applying three statistical tests. We found the relation between the anisotropy and the cluster richness. The relation between the galaxy alignment and the Bautz-Morgan morphological type of the parent cluster is not present. A statistically marginal relation between the velocity dispersion and cluster richness is observed. We also analyzed ellipticities for 6188 low redshift (z < 0.18) poor and rich galaxy structures which have been examined along with their evolution. Finally, we analyzed the Binggeli effect and found that the orientation of galaxy groups in the Local Supercluster (LSC), is strongly correlated with the distribution of neighbouring groups in the scale up to about 20 Mpc. Analysis of galaxy structures from the PF catalog shows quite different situation - the efect is observed only for more elongated structures (e ≤ 0.3). The effect is present in a distance range of about 60 h−1 Mpc.
Tadeusz Banachiewicz in Tartu (1915 to 1918)
Authors: Flin P. , Panko E. 
Published: March 2017

Abstract
Tadeusz Banachiewicz (1882-1954) was an outstanding Polish astronomer, mathematician and geodesist. He was a professor at the Jagiellonian University in Cracow and director of the Astronomical Observatory (1919-1954), and had a strong influence on Polish astronomy. His achievements led to honorary degrees at universities, fellowships in academies of sciences, and the prestige of high positions in international organizations, such as the International Astronomical Union and the Baltic Geodetic Commission. He is known from both his theoretical and observational studies, his famous motto being: “observo ergo sum”. Here we recall three years of his activity in Tartu, where Tadeusz Banachiewicz made the most important steps in his career. He arrived at Yuryev in October of 1915, employed as a young assistant. In March 1918 he became the extraordinary professor and director of the Astronomical Observatory.
Variability of Double-Peaked Emission Lines in AGNs as a Probe of the Broad-Line Region Structure
Authors: Flohic Hélène M. L. G. 
Published: March 2017

AbstractWe demonstrate that the disk-wind model for the broad-line region (BLR) can explain the variability from single-peaked to double-peaked emission line (DPEL) profiles observed in some active galactic nuclei (AGNs) and can produce realistic single-peaked line profiles if the inclination and size of the line-emitting region are restricted. The main drivers of differences in the line profile is the radial density distribution in the wind, which is likely related to the accretion rate of the AGN. We exploit the extreme case of AGNs with DPELs in order to test different models of perturbations in the accretion disk, and find evidences that the outer regions of the disk are likely unstable to self-gravity. Finally, we devise a new monitoring strategy in order to build a rich dataset in a short time.
The Starburst – AGN Connection: a Critical Review
Authors: Rafanelli P. , La Mura G. , Bindoni D. , Ciroi S. , Cracco V. , Di Mille F. , Vaona L. 
Published: March 2017

AbstractNuclear activity and star formation processes represent two key elements in the evolution of galaxies across the cosmic ages. In spite of very different physical backgrounds, several arguments suggest that they should be closely connected. On the basis of simple theoretical considerations, the transport of appreciable amounts of fuel to the AGN scale is very likely to trigger star formation in the gas. Young stellar populations, in their turn, are expected to affect the properties of the interstellar medium, leading to a complex balance of interactions among nuclear activity and star formation. This scenario is also supported by the observation of super-massive black holes and host galaxy properties, which strongly suggest a common evolutionary track. However, despite several years of extensive investigation, the relationship among the two processes still has to be properly explained. Here we provide a review of some of the most important observations, which are relevant to the issue of the connection among AGN and starburst events. Based on a wide sample of observations, we present an analysis of the spectral signatures connected with AGN and star formation activity. Expanding the concept of the distinction among star forming galaxies and the true active nuclei, we provide systematic evidence for a role of recent starburst events in the circum-nuclear regions of active galaxies and discuss the possibility of its influence onto the AGN environment. We also analyze the age, mass and metallicity properties of star-forming and active galaxies, illustrating that they are arranged in a sequence that is consistent with the identified relation.
Stark Broadening and White Dwarfs
Authors: Dimitrijević Milan S. , Kovačević Andjelka , Simić Zoran , Sahal-Bréchot Sylvie 
Published: March 2017

Abstract
White dwarf and pre-white dwarfs are the best types of stars for the application of Stark broadening research results in astrophysics, since in the atmospheres of these stars physical conditions are very favorable for this line broadening mechanism - in hot hydrogen-deficient white dwarfs and pre-white dwarfs Teff = 75 000–180 000 K and log g = 5.5–8 [cgs]. Even for much cooler DA and DB white dwarfs with the typical effective temperatures 10 000-20 000 K, Stark broadening is usually the dominant broadening mechanism. In this review, Stark broadening in white dwarf spectra is considered, and the attention is drawn to the STARK-B database (http://stark-b.obspm.fr/), containing the parameters needed for analysis and synthesis of white dwarf spectra, as well as for the collective efforts to develop the Virtual Atomic and Molecular Data Center.
VAMDC as a Resource for Atomic and Molecular Data and the New Release of VALD
Authors: Kupka F. , Dubernet M.-L. 
Published: March 2017

Abstract
The Virtual Atomic and Molecular Data Centre (VAMDC) is an EU-FP7 project devoted to build a common electronic infrastructure for the exchange and distribution of atomic and molecular data. Within VAMDC scientists from many different disciplines in atomic and molecular physics collaborate with users of their data and also with scientists and engineers from the information and communication technology community. In this presentation, an overview of the current status of VAMDC and its capabilities is provided. In the second part of the presentation I will focus on one of the databases which have become a part of the VAMDC platform, the Vienna Atomic Line Data Base (VALD). VALD has developed into a well-known resource of atomic data for spectroscopy, particularly in astrophysics. A new release, VALD-3, will provide numerous improvements over its predecessor. This particularly relates to the data contents where new sets of atomic data for both precision spectroscopy (i.e., with data for observed energy levels) as well as opacity calculations (i.e., with data involving predicted energy levels) have been included. Data for selected diatomic molecules have been added, and the new system for data distribution and data referencing provides more convenience in using the third release of VALD.
Ab Initio Determination of Atomic Structure and Stark Broadening Parameters: Pb IV and Recent Results
Authors: Hamdi R. , Nessib N. Ben , Dimitrijević M. S. , Sahal-Bréchot S. 
Published: March 2017

Abstract
We present a review of our previous ab initio calculations of Stark broadening parameters using semi-classical perturbation method for the calculation of Stark widths and shifts, and the SUPERSTRUCURE (SST) code for the determination of atomic structure. SST code takes into account the configuration interactions and relativistic effects. New results are also presented for some spectral lines of Pb IV. Energy levels and oscillator strengths are calculated using Hartree-Fock relativistic approach, and the Stark broadening parameters are determined using a semiclassical perturbation approach.
Spectroscopic Observations of the Recurrent Symbiotic Nova V407 Cyg During 2001 - 2009
Authors: Esipov V. F. , Kolotilov E. A. , Komissarova G. V. , Shenavrin V. I. , Tarasova T. N. , Tatarnikov A. M. , Tatarnikova A. A. 
Published: March 2017

Abstract
We analyze the results of our spectroscopic monitoring of V407 Cyg in 2001–2009. the slow decline in optical brightness connected with the evolution of a Z And-type outburst (maximum in 1998) was observed in 2001–2003. the system returned to quiescence in 2004, and its spectrum returned to nearly the same as in 1994. We estimated the hot component’s temperature from the equivalent width of He II 4686 Å to be ~63 000 K . During 2006–2007 there was no clear evidence of the hot component in the spectra. the equivalent width of Hα dropped to 5Å (in 2007). This passive state was similar to previous passive states observed during 2006–2007 and in 1991.
The Long-Term Spectroscopic Misadventures of AG Dra with a Nod Toward V407 Cyg: Degenerates Behaving Badly
Authors: Shore S. N. , Genovali K. , Wahlgren G. M. 
Published: March 2017

Abstract
We present some results of an ongoing study of the long-term spectroscopic variations of AG Dra, a prototypical eruptive symbiotic system. We discuss the effects of the environment and orbital modulation in this system and some of the physical processes revealed by a comparison with the nova outburst of the symbiotic-like recurrent nova V407 Cyg 2010.