bluuebunny/crossref_metadata_2025_split huggingface dataset:
BLISS: quantitative and versatile genome-wide profiling of DNA breaks in situ
Authors: Yan Winston X. , Mirzazadeh Reza , Garnerone Silvano , Scott David , Schneider Martin W. , Kallas Tomasz , Custodio Joaquin , Wernersson Erik , Gao Linyi , Li Yinqing , Federova Yana , Zetsche Bernd , Zhang Feng , Bienko Magda , Crosetto Nicola 
Published: December 2016

AbstractWe present a method for genome-wide DNA double-strand Breaks (DSBs) Labeling In Situ and Sequencing (BLISS) which, compared to existing methods, introduces several key features: 1) high efficiency and low input requirement by in situ DSB labeling in cells or tissue sections directly on a solid surface; 2) easy scalability by performing in situ reactions in multi-well plates; 3) high sensitivity by linearly amplifying tagged DSBs using in vitro transcription; and 4) accurate DSB quantification and control of PCR biases by using unique molecular identifiers. We demonstrate the ability to use BLISS to quantify natural and drug-induced DSBs in low-input samples of cancer cells, primary mouse embryonic stem cells, and mouse liver tissue sections. Finally, we applied BLISS to compare the specificity of CRISPR-associated RNA-guided endonucleases Cas9 and Cpf1, and found that Cpf1 has higher specificity than Cas9. These results establish BLISS as a versatile, sensitive, and efficient method for genome-wide DSB mapping in many applications.
Private sector firms, social responsibility and poverty reduction
Authors: Hipsher Scott 
Published: December 2016

PurposeThe purpose of this paper is to explore the perspectives of workers in one of the least developed economies (Cambodia) on the creation of new job and livelihood opportunities created by foreign firms or foreign investment.Design/methodology/approachQualitative: randomly selected interviews of individuals.FindingsIndividuals working in international organizations find international business activities increase their livelihood options and therefore help to improve their lives.Research limitations/implicationsAn exploratory approach using convenience sampling was taken which limits generalizing the results to a broader population.Practical implicationsThe concepts explored can be used by individual firms when formulating their social responsibility programmes and the ethical implications of their business practices in emerging markets as well as by governments in creating public policies concerning poverty reduction.Social implicationsPresents and respects the views of lower income individuals working in the tourism industry whose voices are often overlooked when corporate social responsibility and public policies are designed.Originality/valueProvides a perspective about poverty reduction of individuals from low-income backgrounds whose lives are directly impacted by international investment and trade.
Organic consumers’ price knowledge, willingness-to-pay and purchase decision
Authors: Rödiger Manika , Plaßmann Sabine , Hamm Ulrich 
Published: December 2016

Purpose
The purpose of this paper is to gain insights into organic consumers’ price sensitivity by investigating price knowledge, willingness-to-pay and real purchase decision.

Design/methodology/approach
Organic food consumers’ price knowledge, willingness-to-pay and real purchase decision were examined in a comprehensive field study with 642 respondents. An innovative method was used to collect data for products that were truly relevant to the respondents: before entering the shop, respondents were asked about the items on their shopping list, the prices they expected to find and the maximum prices they were willing to pay. If respondents stated a willingness-to-pay value below the actual store price, they were approached again after shopping to verify their purchase decision.

Findings
The great majority of respondents failed to estimate the correct store price. The deviation between the estimated price and the actual store price was on average 19.9 per cent. The respondents were willing to pay on average 52.7 per cent above store prices. It was revealed that in 67.0 per cent of the cases, respondents bought a product even though the store price was higher than the willingness-to-pay they stated upon entering the store.

Practical implications
Category-specific insights into price knowledge and willingness-to-pay of organic consumers might be used for price differentiation strategies.

Originality/value
To the authors’ knowledge, this is the first study to investigate organic consumers’ item- and store-specific price knowledge, willingness-to-pay and real purchase decision in a single-source approach.
Festival connections
Authors: Black Niki 
Published: December 2016

Purpose
The purpose of this paper is to examine the contribution of small-scale, rural festivals to the social sustainability of their host communities. Small-scale, community originated festivals proliferate the rural landscape throughout the UK and yet despite this, festival research has focussed predominantly on large, urban events and on their economic impact (Wood, 2009; Gibson and Connell, 2011). This paper seeks to address the perceived research gap by examining these events through a lens of social sustainability.

Design/methodology/approach
The research uses a case study approach focussed on four festivals in Northumberland, UK. Individual interviews and focus groups were conducted with festival organisers, key figures and visitors. Following a constructivist grounded theory method four principle indicators were identified to determine festival contribution to community social sustainability. These indicators are: contribution to community pride and localness, enhancement of knowledge and understanding, contribution to the continuity of local culture and enablement of networks of connectivity.

Findings
The findings demonstrate the networks of connections which festivals enable between the culture, heritage and people (individuals and groups) of a place. By focussing on four indicators the paper shows the social impact of connections through the festival processes and content. The paper argues that small-scale festivals in rural locations can contribute to social sustainability if they demonstrate a balance of both consistency and innovation and accessibility and openness within the locale.

Originality/value
This paper addresses the gap in social impact research into rural festivals and presents an original approach to identify festival impact on community social sustainability.
A 3E typology of visitors at an electronic dance music festival
Authors: Kruger Martinette , Saayman Melville 
Published: December 2016

Purpose
The purpose of this paper is to determine the motives of visitors to an electronic dance music (EDM) festival in South Africa and clustered the participants according to these motives.

Design/methodology/approach
Based on a visitor survey at the oldest EDM festival in South Africa, namely, H2O, five motives for attending H2O were identified (fun and dance; novelty; excitement, group identity and entertainment; lifestyle and well-being; and travel and escape), while the results revealed three clusters of EDM festival visitors: enthusiasts, energizers and electros. The results demonstrated that clustering EDM festival visitors based on their motives is a useful market segmentation tool as it yields a clear and direct profile and understanding of different types of attendees and their preferences.

Findings
The results as well as findings emphasize how EDM events can play a role in expanding tourism, especially youth travel, by hosting more EDM festivals in the country.

Originality/value
The study proposes a 3E typology of EDM festival visitors that could be applied to other EDM festival and event markets. This research, therefore, makes a clear contribution to the literature on EDM festivals and events and the market that this distinct music genre attracts.
Constructs of quality in higher education services
Authors: Sunder M. Vijaya 
Published: December 2016

Purpose
The purpose of this paper is to present various quality constructs, their application, success and shortcomings, in higher education (HE) services.

Design/methodology/approach
This paper aims at reviewing the quality constructs in higher education services through a general review. The paper is organised to highlight different quality practices which higher education institutions have followed from 1990s till date. The paper is scoped to discuss about total quality management (TQM), Kaizen, Six Sigma, Lean and Lean Six Sigma (LSS) comparing their value addition and shortcoming in imbibing quality into the higher education. Publications indexed in Scopus database are considered for the review. The focus of the search in the selected publications was to identify the success and shortcomings of various quality constructs in HE services.

Findings
The requirement for a quality construct in higher education industry is an important finding of the paper. Alongside this, the reasons behind the shortcoming of quality practices used in higher education system were highlighted. The findings include the opportunities for future research for imbibing quality culture in HE.

Research limitations/implications
The literature discussed in the part of the paper is restricted to TQM, Kaizen, Six Sigma, Lean and LSS. Though the usage of such quality practices in HE originated in 1990s, there is no one robust sustainable practice till date, which proved to be a pacesetter. This paper validates this assertion, which helps both academicians and practitioners with a new perspective.

Originality/value
This paper would serve as an excellent resource for both academicians and practitioners to understand the history of quality which contributed to the improvement in HE services, and how the quality excellence has evolved over the years. The paper concludes with a discussion on opportunities for future research to develop quality frameworks for HE services.
Measuring business performance in the airport context: a critical review of literature
Authors: Fasone Vincenzo , Zapata-Aguirre Sandra 
Published: December 2016

Purpose
Over 15 years have passed since the first paper was published applying data envelopment analysis (DEA) to measure airport productivity. Since then, a wave of studies has appeared refining and validating this technique as one of the most reliable in the airport context. The purpose of this paper is to conduct a critical review of this accumulated literature.

Design/methodology/approach
This paper presents an exhaustive review of approximately 60 peer-reviewed published papers on business performance measurement through DEA applications in the airport industry.

Findings
The paper analyses the research on DEA technique chronologically and by geography. Managerial and academic practitioners’ interest in conducting performance measurement studies has grown and benchmarking techniques have become more sophisticated.

Research limitations/implications
Despite the popularity of the methodological framework of DEA, it can be improved by further research to continue refining and exploiting deeply the basic DEA scores. Some innovations have appeared from studies using alternative approaches to DEA, e.g. a Bayesian approach.

Practical implications
The conclusions explore the research contribution, its final value delivered to airport management and some practical aspects and recommendations for the selected field of work.

Originality/value
The paper explores the contribution of research to final value delivered to airport management by describing the main complementary procedures refining DEA technique scores for improving the operational efficiencies of airports through benchmarking. As well as by presenting the results of the assessment of major determinants of efficiency at airports around the world.
Healthcare service quality model
Authors: Sumaedi Sik , Yarmen Medi , Yuda Bakti I. Gede Mahatma 
Published: December 2016

Purpose
The purpose of this paper is to develop and test a multi-level healthcare service quality (HSQ) model in Jakarta, Indonesia.

Design/methodology/approach
The research used a quantitative research method. Data were collected via a survey with questionnaire. The respondents are 154 patients of a healthcare institution in Jakarta, Indonesia.

Findings
The research result shows a multi-level HSQ model. The HSQ model consists of three primary dimensions, namely, healthcare service outcome, healthcare service interaction, and healthcare service environment. Healthcare service outcome has three subdimensions, i.e. waiting time, medicine, and effectiveness. Healthcare service interaction has three dimensions, namely, soft interaction, medical personnel expertise, and hard interaction. Healthcare service environment has two dimensions, which are equipment condition and ambient condition.

Research limitations/implications
This research was only conducted in one healthcare institution in Jakarta, Indonesia. The data collection using convenience sampling method as well as the use of small sample size caused the limitation of the research results in representing across the customer of the healthcare institution. This study can be replicated with larger sample size and involving more healthcare institutions in order to examine the stability of the HSQ model.

Practical implications
Healthcare institution’s managers can use the HSQ model to monitor, measure, and improve their service quality.

Originality/value
There is a lack of research that develops and tests HSQ model based on multi-level approach in the context of developing country. This paper has fulfilled the gap.
Effect of bank-specific and governance-specific variables on the productivity and profitability of banks
Authors: Narwal Karam Pal , Pathneja Shweta 
Published: December 2016

Purpose
The purpose of this paper is to analyze the effect of bank-related variables and corporate governance-related variables on the productivity and profitability of public and private sector banks in India.

Design/methodology/approach
The Malmquist productivity index is applied to determine the productivity of different banks. Further, return on average assets is used as profitability of banks. The regression analysis is further used to assess the effect of different bank-related and governance-related variables on performance of banks.

Findings
Nearly all the bank-specific variables explain the productivity and profitability of banks but a weak relationship is observed between individual governance variables and performance variables. Two governance variables, i.e. board meetings and remuneration explicate the profitability of the public sector banks and only duality explains the profitability of the private sector banks. No significance is found between productivity and governance variables.

Originality/value
The study addresses the embryonic issue of corporate governance in the banking sector. The uniqueness of the paper lies in that no study has evaluated the effect of these variables on productivity and profitability of banks simultaneously.
An examination of the status and evolution of country image research
Authors: Lu Irene R.R. , Heslop Louise A. , Thomas D. Roland , Kwan Ernest 
Published: December 2016

PurposeCountry image (CI) has been one of the most studied topics in international business, marketing, and consumer behaviour of the past five decades. Nevertheless, there has been no critical assessment of this field of research. The purpose of this paper is to understand the status and evolution of CI research.Design/methodology/approachThe authors review 554 articles published in academic journals over 35 years. The authors examine publication, authorship, and research procedure trends in these articles as an empirical and quantitative assessment of the field. The authors identify weaknesses and strengths, and the authors address disconcerting and encouraging trends.FindingsThe authors find a number of laudatory trends: CI research is becoming less US-centric, more theory driven, more sophisticated in methodology, evaluating more diverse product categories, and making use of multiple cue studies. There are, however, two major methodological concerns: poor replication and questionable generalizability of findings. The authors also noted the influence of CI articles has been decreasing, as well as their rate of publication in top tier journals.Originality/valueSince the authors present data that reflect actual practices in the field and how such practices have changed across time, the authors believe the study is of substantial value to CI researchers, journal editors, and instructors whose curriculum includes CI. The critical assessment and subsequent recommendations are accordingly empirically justified.
The variable nature of country-to-brand association and its impact on the strength of the country-of-origin effect
Authors: Andéhn Mikael , L’Espoir Decosta Patrick 
Published: December 2016

Purpose
Recent research has shown that the country-of-origin (COO) effect – the influence on consumers’ attitudes and purchase behavior derived from a brand’s perceived association with a country – is inextricably linked to consumer perception. The purpose of this paper is to examine this shift by considering origin as a characteristic derived from perceived association and also by proposing that this association varies by degree, rather than simply acting as a binary attribute in its effect on consumer attitudes.

Design/methodology/approach
Data from a test series in which respondents (n=100) rated 38 brand-country pairs were put to split-half multi-group analysis tests to capture the moderating influence of association strength (AS) on several facets of country image (CI) simultaneously.

Findings
AS is a variable that exerts a moderating influence on how different dimensions of CI influence consumers’ evaluation of brands.

Research limitations/implications
The findings indicate that origin, as a characteristic, should be considered an association that is variable by degree and not as dichotomous. The implications of such a shift are broad, not only for the theoretical understanding of the COO effect but also for marketing and brand management practice. Accounting for AS allows for more accurate prediction of how consumers will react to COO.

Originality/value
The paper explicitly demonstrates that the strength of country-brand association moderates COO’s influence on brand equity. Such a relationship had previously only been theoretically implied but had not been empirically tested across multiple categories of products on multiple levels of CI.
Factors influencing online learning in an organisational context
Authors: Montgomerie Kristina , Edwards Margot , Thorn Kaye 
Published: December 2016

Purpose
The purpose of this paper is to understand the factors perceived to influence successful online learning in organisations.

Design/methodology/approach
Utilising an exploratory, qualitative approach, 20 participants were involved in semi-structured interviews before, during and after their involvement in an online development programme.

Findings
Key factors perceived to influence participants’ learning, in order of their perceived influence, are online considerations (such as time allocation and discipline), peer support and technical delivery. Organisational culture was also found to have some influence, however further research is required to establish the extent this influence. The compounding or mitigating effect of the interplays of these factors was highlighted.

Research limitations/implications
Although the study is limited by its small sample, it provides a basis for the further exploration of online learning in an organisational context and draws attention to the effect of the interplay of factors affecting learning. Research into the longitudinal influence of online learning in organisations, and particularly research which enables breakdown by learning style may assist in the development of programmes suitable for most participants.

Originality/value
Online learning is becoming a common tool for employee development in the workplace and yet little is known about the factors that influence learning in this environment. This paper offers new insights into that gap through a progressive evaluation of factors facilitating or inhibiting online learning.
Burden of herpes zoster and postherpetic neuralgia in Japanese adults 60 years of age or older: Results from an observational, prospective, physician practice‐based cohort study
Authors: Sato Keiko , Adachi Koichi , Nakamura Hiroyuki , Asano Kazuhiro , Watanabe Akihiro , Adachi Riri , Kiuchi Mariko , Kobayashi Keiju , Matsuki Taizo , Kaise Toshihiko , Gopala Kusuma , Holl Katsiaryna 
Published: December 2016

AbstractApproximately one in three persons will develop herpes zoster during their lifetime, and it can lead to serious complications such as postherpetic neuralgia. However, evidence on burden of herpes zoster and postherpetic neuralgia in Japan is limited. This prospective, observational, multicenter, physician practice‐based cohort study was conducted in Kushiro, Hokkaido, Japan (Clinicaltrials.gov identifier NCT01873365) to assess the incidence and hospitalization rates of herpes zoster, and the proportion, clinical burden and risk factors for postherpetic neuralgia in adults aged 60 years or more. Within the study area, 800 subjects developed herpes zoster and 412 were eligible for the study. Herpes zoster incidence was 10.2/1000 person‐years and higher among women and older subjects. Subjects with herpes zoster required on average 5.7 outpatient consultations. Herpes zoster‐associated hospitalization rate was 3.4% (27/800). The proportion of postherpetic neuralgia and other complications was 9.2% (38/412) and 26.5% (109/412), respectively. Statistically significant association with the development of postherpetic neuralgia was male sex (odds ratio [OR], 2.51; 95% confidence interval [CI], 1.17–5.38), age of 70–74 years (OR, 3.51; 95% CI, 1.09–11.3), immunosuppressive therapy (OR, 6.44; 95% CI, 1.26–32.9), severe herpes zoster pain at first consultation (OR, 3.08; 95% CI, 1.10–8.62) and rash on upper arms (vs no rash on upper arms; OR, 3.46; 95% CI, 1.10–10.9). Considerable herpes zoster and postherpetic neuralgia burden exists among elderly in Japan, and there may be predictive factors at the first visit which could be indicative of the risk of developing postherpetic neuralgia.
Might constraint be compatible with care? Home care as a situational ethics
Authors: Hennion Antoine , Vidal‐Naquet Pierre A. 
Published: December 2016

AbstractRespecting the autonomy and will of people has legitimately led to strictly control the use of constraint in care activities, and promote a care ethics centred around people's needs and wills. But constraint is underlying in any action aiming at making people do something, even with their consent, especially when their ability to evaluate what is best for them may be altered. Ceaselessly present in care, this ordinary, silent constraint should not be only deemed as a necessary evil to be prevented. In contrast with this legally‐based view, the paper adopts a pragmatic perspective. Leaning on minute case studies carried out at disable people's homes, the empirical section takes up some key troubling moments between caregivers and patients as trials capable of revealing ‘constraint in practice’: a situation of uncertainty, doubt, hesitations on the appraisal of what is happening and how to deal with it, banning any clear‐cut distinction between technical gestures and moral values. Having outlined the characters of such a ‘situational ethics’, the authors argue in conclusion that, provided caregivers are never quits with its use, constraint is compatible with care, and assume that care theories could fruitfully support this advocacy to ‘maintaining the trouble’ in care practices.