bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMAL RESULTS ON RECOGNIZABILITY FOR INFINITE TIME REGISTER MACHINES
Authors: CARL MERLIN 
Published: December 2015

AbstractExploring further the properties of ITRM-recognizable reals started in [1], we provide a detailed analysis of recognizable reals and their distribution in Gödels constructible universe L. In particular, we show that new unrecognizable reals are generated at every index $\gamma \, \ge \,\omega _\omega ^{CK}$. We give a machine-independent characterization of recognizability by proving that a real r is recognizable if and only if it is ${\Sigma _1}$-definable over ${L_{\omega _\omega ^{CK,\,r}}}$ and that $r\, \in \,{L_{\omega _\omega ^{CK,\,r}}}$ for every recognizable real r and show that either every or no r with $r\, \in \,{L_{\omega _\omega ^{CK,\,r}}}$ generated over an index stage ${L_\gamma }$ is recognizable. Finally, the techniques developed along the way allow us to prove that the halting number for ITRMs is recognizable and that the set of ITRM-computable reals is not ITRM-decidable.
Triadic analysis of affiliation networks
Authors: BRUNSON JASON CORY 
Published: December 2015

AbstractTriadic closure has been conceptualized and measured in a variety of ways, most famously the clustering coefficient. Existing extensions to affiliation networks, however, are sensitive to repeat group attendance, which does not reflect common interpersonal interpretations of triadic closure. This paper proposes a measure of triadic closure in affiliation networks designed to control for this factor, which manifests in bipartite models as biclique proliferation. To avoid arbitrariness, the paper introduces a triadic framework for affiliation networks, within which a range of measures can be defined; it then presents a set of basic axioms that suffice to narrow this range to the one measure. An instrumental assessment compares the proposed and two existing measures for reliability, validity, redundancy, and practicality. All three measures then take part in an investigation of three empirical social networks, which illustrates their differences.
Cross-sectional association between serum concentrations ofn-3 long-chain PUFA and depressive symptoms: results in Japanese community dwellers
Authors: Horikawa Chika , Otsuka Rei , Kato Yuki , Nishita Yukiko , Tange Chikako , Kakutani Saki , Rogi Tomohiro , Kawashima Hiroshi , Shibata Hiroshi , Ando Fujiko , Shimokata Hiroshi 
Published: December 2015

AbstractThe effect ofn-3 long-chain PUFA (n-3 LCPUFA) on depression in healthy subjects is unclear, and most of the previous studies have focused on populations eating Western diets with lower fish intake. The present study investigated the association between blood levels ofn-3 LCPUFA and depressive symptoms in Japanese community dwellers with highern-3 LCPUFA blood levels. A cross-sectional study was conducted from 2006 to 2008, including 1050 men and 1073 women aged 40 years or older from the National Institute for Longevity Sciences – the Longitudinal Study of Aging. The Center for Epidemiologic Studies Depression Scale (CES-D) was used to assess depressive symptoms. Multiple logistic regression analysis was performed to estimate the OR and 95 % CI for a CES-D score ≥16. Serum concentrations ofn-3 PUFA, but notn-6 PUFA, were inversely associated with depressive symptoms. Compared with the lowest quintile, the adjusted OR for serum EPA at the fourth and fifth quintiles were 0·55 (95 % CI 0·35, 0·85) and 0·64 (95 % CI 0·42, 0·98), respectively, and at the fifth quintile for DHA it was 0·58 (95 % CI 0·37, 0·92), for the presence of depressive symptoms (Pfor trend=0·013 and 0·011, respectively). Serum levels of EPA and DHA were inversely associated with depressive symptoms in Japanese community dwellers with higher blood levels ofn-3 LCPUFA, suggesting thatn-3 LCPUFA intakes corresponding to higher levels in a Japanese population may have implications for a lower prevalence of depression.
Probability and Bias in Generating Supersoluble Groups
Authors: Crestani Eleonora , De Franceschi Giovanni , Lucchini Andrea 
Published: December 2015

AbstractWe discuss some questions related to the generation of supersoluble groups. First we prove that the number of elements needed to generate a finite supersoluble groupGwith good probability can be quite a lot larger than the smallest cardinality d(G) of a generating set ofG. Indeed, ifGis the free prosupersoluble group of rankd⩾ 2 and dP(G) is the minimum integerksuch that the probability of generatingGwithkelements is positive, then dP(G) = 2d+ 1. In contrast to this, ifk–d(G) ⩾ 3, then the distribution of the first component in ak-tuple chosen uniformly in the set of all thek-tuples generatingGis not too far from the uniform distribution.
Solutions ofp-Laplace Equations with Infinite Boundary Values: The case of Non-Autonomous and Non-Monotone Nonlinearities
Authors: Karls Michael A. , Mohammed Ahmed 
Published: December 2015

AbstractFor a non-negative and non-trivial real-valued continuous functionhΩ× [0, ∞) such thath(x, 0) = 0 for allx∈Ω, we study the boundary-value problemwhereΩ⊆ ℝN,N⩾ 2, is a bounded smooth domain and Δp:= div(|Du|p–2DDu) is thep-Laplacian. This work investigates growth conditions onh(x, t) that would lead to the existence or non-existence of distributional solutions to (BVP). In a major departure from past works on similar problems, in this paper we do not impose any special structure on the inhomogeneous termh(x, t), nor do we require any monotonicity condition onhin the second variable. Furthermore,h(x, t) is allowed to vanish in either of the variables.
Can sensitivity to temperature during germination help predict global warming vulnerability?
Authors: Cochrane Anne 
Published: December 2015

AbstractSeed germination is vital for persistence in species that rely on seeds for post-disturbance regeneration. It is a high-risk phase and vulnerable to environmental parameters. Here, I assessed temperature sensitivity for germination in Banksia L.f. (Proteaceae) from south-western Australia, screening all 38 endemic obligate seeder species. A bi-directional temperature gradient plate with 49 temperature combinations (constant and fluctuating) between 5 and 40°C was used to profile germination temperature requirements and identify upper and lower temperature thresholds for germination. Using these data the impact of increasing temperatures on germination in these species was modelled under high and low greenhouse gas scenarios for 2050 and 2070. The results suggest that many Banksia species from the region have wide physiological tolerance for high germination temperatures, although a number of common, but geographically restricted species, such as B. praemorsa, B. oreophila and B. quercifolia, have more narrow temperature windows for germination than at least one of the rarer species (B. verticillata). Only B. dryandroides is expected to decline in germination in the future; however, the optimal germination timing for many species is predicted to occur later under climate warming. In conjunction with declining rainfall, this germination delay will place seedlings closer to the summer dry in this seasonal Mediterranean-climate ecosystem and thus they will be more vulnerable to desiccation. The framework developed here can be used to identify vulnerable species for monitoring of early population decline.
Usefulness of maximal oxygen pulse in timing of pulmonary valve replacement in patients with isolated pulmonary regurgitation
Authors: Legendre Antoine , Richard Ruddy , Pontnau Florence , Jais Jean-Philippe , Dufour Marc , Grenier Olivier , Mousseaux Elie , Ladouceur Magalie , Iserin Laurence , Bonnet Damien 
Published: December 2015

Patients with pulmonary regurgitation after tetralogy of Fallot repair have impaired aerobic capacity; one of the reasons is the decreasing global ventricular performance at exercise, reflected by decreasing peak oxygen pulse. The aims of our study were to evaluate the impact of pulmonary valve replacement on peak oxygen pulse in a population with pure pulmonary regurgitation and with different degrees of right ventricular dilatation and to determine the predictors of peak oxygen pulse after pulmonary valve replacement.The mean and median age at pulmonary valve replacement was 27 years. Mean pre-procedural right ventricular end-diastolic volume was 182 ml/m2. Out of 24 patients, 15 had abnormal peak oxygen pulse before pulmonary valve replacement. We did not observe a significant increase in peak oxygen pulse after pulmonary valve replacement (p=0.76). Among cardiopulmonary test/MRI/historical pre-procedural parameters, peak oxygen pulse appeared to be the best predictor of peak oxygen pulse after pulmonary valve replacement (positive and negative predictive values, respectively, 0.94 and 1). After pulmonary valve replacement, peak oxygen pulse was well correlated with left ventricular stroke and end-diastolic volumes (r=0.67 and 0.68, respectively).Our study confirms the absence of an effect of pulmonary valve replacement on peak oxygen pulse whatever the initial right ventricular volume, reflecting possible irreversible right and/or left ventricle lesions. Pre-procedural peak oxygen pulse seemed to well predict post-procedural peak oxygen pulse. These results encourage discussions on pulmonary valve replacement in patients showing any decrease in peak oxygen pulse during their follow-up.
A Direct Comparison of Real-World and Virtual Navigation Performance in Chronic Stroke Patients
Authors: Claessen Michiel H.G. , Visser-Meily Johanna M.A. , de Rooij Nicolien K. , Postma Albert , van der Ham Ineke J.M. 
Published: December 2015

AbstractObjectives:An increasing number of studies have presented evidence that various patient groups with acquired brain injury suffer from navigation problems in daily life. This skill is, however, scarcely addressed in current clinical neuropsychological practice and suitable diagnostic instruments are lacking. Real-world navigation tests are limited by geographical location and associated with practical constraints. It was, therefore, investigated whether virtual navigation might serve as a useful alternative.Methods:To investigate the convergent validity of virtual navigation testing, performance on the Virtual Tübingen test was compared to that on an analogous real-world navigation test in 68 chronic stroke patients. The same eight subtasks, addressing route and survey knowledge aspects, were assessed in both tests. In addition, navigation performance of stroke patients was compared to that of 44 healthy controls.Results:A correlation analysis showed moderate overlap (r=.535) between composite scores of overall real-world and virtual navigation performance in stroke patients. Route knowledge composite scores correlated somewhat stronger (r=.523) than survey knowledge composite scores (r=.442). When comparing group performances, patients obtained lower scores than controls on seven subtasks. Whereas the real-world test was found to be easier than its virtual counterpart, no significant interaction-effects were found between group and environment.Conclusions:Given moderate overlap of the total scores between the two navigation tests, we conclude that virtual testing of navigation ability is a valid alternative to navigation tests that rely on real-world route exposure. (JINS, 2016,22, 467–477)
A Cross-National Study on the Psychometric Quality of the Italian	Version of the Dutch Work Addiction Scale (DUWAS)
Authors: Balducci Cristian , Avanzi Lorenzo , Consiglio Chiara , Fraccaroli Franco , Schaufeli Wilmar 
Published: December 2015

Abstract. We investigated the psychometric properties of the Italian version of the Dutch Work Addiction Scale (DUWAS) by using an Italian sample (N = 1,027) and a comparable Dutch sample (N = 7,523). We first conducted multigroup confirmatory factor analysis and reliability analysis. We then examined the correlations of the DUWAS with job demands, work-family conflict, job-related affective well-being, and psychological and physical strain. Results showed that a two-factor solution of the DUWAS was equivalent across the Italian and Dutch samples, with data supporting factor variance and covariance equivalence in addition to metric equivalence. Internal consistencies of the DUWAS and its subscales were adequate, and test-retest reliability showed a strong stability of the measure at one year. The DUWAS and its subscales showed a pattern of correlations in the expected direction with the adopted criterion measures. Overall, the Italian version of the DUWAS shows adequate validity and reliability.
The Psychometric Properties of the Scale of Retired Spousal	Intrusion
Authors: Bozoglan Bahadir 
Published: December 2015

Abstract. This study examined the psychometric properties of Retired Spousal Intrusion Scale (SRSI). The calibration study was conducted with a sample of women (n = 687) whose husbands were retired, resulting in a one factor scale consisting of six items. Validation study, discriminant validity and test-retest were conducted in a second sample of women (n = 756) whose husbands were retired. The results of the confirmatory factor analysis revealed that the unidimensional factor model had adequate fit with values x2/df = 4.61, GFI = .98, AGFI = .96, CFI = .96, RMSEA = .06, SRMR = .05. In addition, the correlation of the SRSI with conceptually unrelated measures (dyadic adjustment scale and quality of life) supported the discriminant validity of the SRSI. Finally, analyses showed that SRSI is a valid and reliable measure to assess retired husbands’ intrusion on their wives.
Identification of putative novel O-glycosylations in the NK killer receptor Ncr1 essential for its activity
Authors: Glasner Ariella , Roth Ziv , Varvak Alexander , Miletic Antonija , Isaacson Batya , Bar-On Yotam , Jonjic Stipan , Khalaila Isam , Mandelboim Ofer 
Published: December 2015

AbstractNatural killer (NK) cells kill tumor and virus-infected cells using activating NK cell receptors. One of the major NK-activating receptors is NKp46 and its mouse ortholog Ncr1. NKp46/Ncr1 is expressed exclusively on NK cells and on a subset of innate lymphoid cells. NKp46/Ncr1 was shown to be involved in a myriad of pathologies and immunological settings. Specifically, NKp46/Ncr1 was shown to interact with the viral hemagglutinin (HA) protein and with an unknown tumor/cellular ligand. NKp46 and Ncr1 are structurally similar; however, they are substantially different in their glycosylation patterns. Although the human NKp46 carries both O- and N-glycosylations that are essential for its activity, the mouse Ncr1 was predicted to have N-linked glycosylations only. Here we discovered using prediction algorithms and high-performance liquid chromatography analysis that Ncr1 carries two putative novel O-glycosylations, one of which (Thr 225) is conserved in NKp46. We next used surface plasmon resonance, biochemical, mutational and functional in vitro and in vivo assays to demonstrate that the putative O-glycosylations of Ncr1 are critical for its function.
Patterns and functional implications of rare germline variants across 12 cancer types
Authors: Lu Charles , Xie Mingchao , Wendl Michael C. , Wang Jiayin , McLellan Michael D. , Leiserson Mark D. M. , Huang Kuan-lin , Wyczalkowski Matthew A. , Jayasinghe Reyka , Banerjee Tapahsama , Ning Jie , Tripathi Piyush , Zhang Qunyuan , Niu Beifang , Ye Kai , Schmidt Heather K. , Fulton Robert S. , McMichael Joshua F. , Batra Prag , Kandoth Cyriac , Bharadwaj Maheetha , Koboldt Daniel C. , Miller Christopher A. , Kanchi Krishna L. , Eldred James M. , Larson David E. , Welch John S. , You Ming , Ozenberger Bradley A. , Govindan Ramaswamy , Walter Matthew J. , Ellis Matthew J. , Mardis Elaine R. , Graubert Timothy A. , Dipersio John F. , Ley Timothy J. , Wilson Richard K. , Goodfellow Paul J. , Raphael Benjamin J. , Chen Feng , Johnson Kimberly J. , Parvin Jeffrey D. , Ding Li 
Published: December 2015

AbstractLarge-scale cancer sequencing data enable discovery of rare germline cancer susceptibility variants. Here we systematically analyse 4,034 cases from The Cancer Genome Atlas cancer cases representing 12 cancer types. We find that the frequency of rare germline truncations in 114 cancer-susceptibility-associated genes varies widely, from 4% (acute myeloid leukaemia (AML)) to 19% (ovarian cancer), with a notably high frequency of 11% in stomach cancer. Burden testing identifies 13 cancer genes with significant enrichment of rare truncations, some associated with specific cancers (for example,RAD51C,PALB2andMSH6in AML, stomach and endometrial cancers, respectively). Significant, tumour-specific loss of heterozygosity occurs in nine genes (ATM,BAP1,BRCA1/2,BRIP1,FANCM,PALB2andRAD51C/D). Moreover, our homology-directed repair assay of 68BRCA1rare missense variants supports the utility of allelic enrichment analysis for characterizing variants of unknown significance. The scale of this analysis and the somatic-germline integration enable the detection of rare variants that may affect individual susceptibility to tumour development, a critical step toward precision medicine.
Yak whole-genome resequencing reveals domestication signatures and prehistoric population expansions
Authors: Qiu Qiang , Wang Lizhong , Wang Kun , Yang Yongzhi , Ma Tao , Wang Zefu , Zhang Xiao , Ni Zhengqiang , Hou Fujiang , Long Ruijun , Abbott Richard , Lenstra Johannes , Liu Jianquan 
Published: December 2015

AbstractYak domestication represents an important episode in the early human occupation of the high-altitude Qinghai-Tibet Plateau (QTP). The precise timing of domestication is debated and little is known about the underlying genetic changes that occurred during the process. Here we investigate genome variation of wild and domestic yaks. We detect signals of selection in 209 genes of domestic yaks, several of which relate to behaviour and tameness. We date yak domestication to 7,300 years before present (yr BP), most likely by nomadic people, and an estimated sixfold increase in yak population size by 3,600 yr BP. These dates coincide with two early human population expansions on the QTP during the early-Neolithic age and the late-Holocene, respectively. Our findings add to an understanding of yak domestication and its importance in the early human occupation of the QTP.
Atomic scale simulation of carbon nanotube nucleation from hydrocarbon precursors
Authors: Khalilov Umedjon , Bogaerts Annemie , Neyts Erik C. 
Published: December 2015

AbstractAtomic scale simulations of the nucleation and growth of carbon nanotubes is essential for understanding their growth mechanism. In spite of over twenty years of simulation efforts in this area, limited progress has so far been made on addressing the role of the hydrocarbon growth precursor. Here we report on atomic scale simulations of cap nucleation of single-walled carbon nanotubes from hydrocarbon precursors. The presented mechanism emphasizes the important role of hydrogen in the nucleation process, and is discussed in relation to previously presented mechanisms. In particular, the role of hydrogen in the appearance of unstable carbon structures during in situ experimental observations as well as the initial stage of multi-walled carbon nanotube growth is discussed. The results are in good agreement with available experimental and quantum-mechanical results, and provide a basic understanding of the incubation and nucleation stages of hydrocarbon-based CNT growth at the atomic level.
A self-healable and highly stretchable supercapacitor based on a dual crosslinked polyelectrolyte
Authors: Huang Yan , Zhong Ming , Huang Yang , Zhu Minshen , Pei Zengxia , Wang Zifeng , Xue Qi , Xie Xuming , Zhi Chunyi 
Published: December 2015

AbstractSuperior self-healability and stretchability are critical elements for the practical wide-scale adoption of personalized electronics such as portable and wearable energy storage devices. However, the low healing efficiency of self-healable supercapacitors and the small strain of stretchable supercapacitors are fundamentally limited by conventional polyvinyl alcohol-based acidic electrolytes, which are intrinsically neither self-healable nor highly stretchable. Here we report an electrolyte comprising polyacrylic acid dual crosslinked by hydrogen bonding and vinyl hybrid silica nanoparticles, which displays all superior functions and provides a solution to the intrinsic self-healability and high stretchability problems of a supercapacitor. Supercapacitors with this electrolyte are non-autonomic self-healable, retaining the capacitance completely even after 20 cycles of breaking/healing. These supercapacitors are stretched up to 600% strain with enhanced performance using a designed facile electrode fabrication procedure.
Stimulated Brillouin Scattering Microscopic Imaging
Authors: Ballmann Charles W. , Thompson Jonathan V. , Traverso Andrew J. , Meng Zhaokai , Scully Marlan O. , Yakovlev Vladislav V. 
Published: December 2015

AbstractTwo-dimensional stimulated Brillouin scattering microscopy is demonstrated for the first time using low power continuous-wave lasers tunable around 780 nm. Spontaneous Brillouin spectroscopy has much potential for probing viscoelastic properties remotely and non-invasively on a microscopic scale. Nonlinear Brillouin scattering spectroscopy and microscopy may provide a way to tremendously accelerate the data aquisition and improve spatial resolution. This general imaging setup can be easily adapted for specific applications in biology and material science. The low power and optical wavelengths in the water transparency window used in this setup provide a powerful bioimaging technique for probing the mechanical properties of hard and soft tissue.
Mid-infrared laser emission from Cr:ZnS channel waveguide fabricated by femtosecond laser helical writing
Authors: Peng Ya-Pei , Zou Xiao , Bai Zhengyuan , Leng Yuxin , Jiang Benxue , Jiang Xiongwei , Zhang Long 
Published: December 2015

AbstractThe operation of a mid-infrared laser at 2244 nm in a Cr:ZnS polycrystalline channel waveguide fabricated using direct femtosecond laser writing with a helical movement technique is demonstrated. A maximum power output of 78 mW and an optical-to-optical slope efficiency of 8.6% are achieved. The compact waveguide structure with 2 mm length was obtained through direct femtosecond laser writing, which was moved on a helical trajectory along the laser medium axis and parallel to the writing direction.
Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications
Authors: Matsunaga Ken-ichiro , Kimoto Michiko , Hanson Charlotte , Sanford Michael , Young Howard A. , Hirao Ichiro 
Published: December 2015

AbstractWe present a remodeling method for high-affinity unnatural-base DNA aptamers to augment their thermal stability and nuclease resistance, for use as drug candidates targeting specific proteins. Introducing a unique mini-hairpin DNA provides robust stability to unnatural-base DNA aptamers generated by SELEX using genetic alphabet expansion, without reducing their high affinity. By this method, >80% of the remodeled DNA aptamer targeting interferon-γ (KD of 33 pM) survived in human serum at 37 °C after 3 days under our experimental conditions and sustainably inhibited the biological activity of interferon-γ.