bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green synthesis of CdFe2O4 by Terminalia catappa leave extract for photodegradation methyl red dye by response surface methodology
Authors: Hariani Poedji Loekitowati , Salni Salni , Yusmartini Eka Sri , Aprinati Nabila , Ahadito Bijak Riyandi 
Published: October 2024

Green synthesis using plant extracts is an eco-friendly approach that reduces the hazards associated with chemical usage. This study aimed to synthesize a CdFe2O4 ferrite compound utilizing Terminalia catappa leaves extract and evaluate its photocatalytic efficiency in degrading Methyl red dye. The X-ray diffraction (XRD) analysis confirms the synthesis of CdFe2O4, which has a crystallite size mean of 18.10 nm. The composite exhibits magnetic properties with a saturation magnetization of 28.34 emu/g, a band gap of 1.78 eV, and a BET surface area of 84.23 m2/g. The optimal photodegradation process was determined using Response Surface Methodology (RSM) based on an experiment with Central Composite Design (CCD). The variables examined included the solution pH, the initial concentration of the dye, and the irradiation time. The interplay of three variables demonstrated their reciprocal influence on photodegradation efficiency. The quadratic model is appropriate for modeling the photodegradation of Methyl red dye. The photodegradation efficiency of 96.56% is achieved under optimal conditions, which include a pH of 6.33, an initial dye concentration of 39.93 mg/L, and an irradiation time of 52.26 min. Empirical investigations on the reusability of CdFe2O4 have shown remarkable stability. Experimental kinetics confirm that the pseudo-first-order model is a suitable description for the photodegradation of Methyl red dye by CdFe2O4.
The novel Zn-doped hexagonal perovskite Ba7In6Al2O19: electrical conductivity and hydration
Authors: Animitsa Irina , Korona Daniil , Bushueva Arina , Andreev Roman , Nokhrin Sergey 
Published: October 2024

The novel phase Ba7In5.9Zn0.1Al2O18.95 with hexagonal perovskite structure was obtained by solid-state technique. The substitution of In3+ by the Zn2+ leads to the expansion of the lattice parameters and cell volume. It was established that the investigated sample is capable of water incorporation from the gas phase; the degree of hydration reaches 1.42 mol H2O, which is significantly higher than that for the undoped phase (0.41 mol H2O). This is a result of the expansion of the hexagonal layer that facilitates the placement of OH–-groups. The oxide-ion and proton conductivities for the doped Ba7In5.9Zn0.1Al2O18.95 sample were higher than those for the undoped composition, Ba7In6Al2O19, by 0.50 and 0.75 orders of magnitude (500 °C), respectively. The new phase Ba7In5.9Zn0.1Al2O18.95 demonstrates the predominant protonic conductivity at Т ≤ 500 °C and pH2O = 1.93·10−2 atm.
Reproducing Experimental H/V Spectral Ratios of Ambient Vibrations: Empirical Testing of Current Numerical Models
Authors: Tanzini Anna , Paolucci Enrico , Albarello Dario 
Published: October 2024

Abstract
Horizontal-to-vertical spectral ratios of ambient vibrations represent an important tool to provide information about the seismic configurations of subsoil. This requires the application of inversion procedures based on numerical models aiming at reproducing observations from hypothetical subsoil configurations. In the current literature, several models have been proposed on purpose, which, however, provide different outcomes when applied to the same configuration. To evaluate how and at what extent the proposed models can fit observations, experimental ambient vibration measurements have been collected at 116 sites in central Italy, in which reliable VS and VP profiles were available from standardized downhole measurements. The comparison between experimental curves and outcomes from all the alternative models proposed in the literature has been carried out. This comparison confirms some theoretical findings about the best-performing models but also reveals that a significant fit is obtained only in about 80% of cases. This suggests that all the considered models present important limitations, possibly related to the general assumption of a 1D subsoil configuration and suggests caution in considering outcomes of the current inversion procedures.
New Aspects of the Antibiotics Use in Ophthalmology: the View of a Clinical Pharmacologist
Authors: Knorring G. Yu. 
Published: October 2024

For infectious and inflammatory eye lesions, the main methods of controlling pathogens include antibacterial agents of various classes and antiseptics. However, the use of these agents has a number of limitations: they are able to act primarily on the surface of the eye tissue, and in accordance with clinical recommendations, they should be used as an addition to antibacterial therapy.Antibacterial therapy remains the main recommendation for the treatment of bacterial eye infections, both in the anterior segment and in deeper lesions. In most countries, drugs from the group of fluoroquinolones and aminoglycosides are more often prescribed empirically, to which an acceptable level of sensitivity of microorganisms remains. Among aminoglycosides, the greatest sensitivity of eye infection pathogens is currently determined to netilmicin.The review examines the prospects and effectiveness of using netilmicin as monotherapy, as well as in combination with fluoroquinolones for topical treatment of bacterial infections in ophthalmology, and provides examples of the successful use of netilmicin.
The Potential of a Laser-Aspiration Solution for Refractive Lens Exchange
Authors: Arakelyan D. E. , Kopaev S. Yu. , Il’inskaya I. A. , Pominova V. V. 
Published: October 2024

Introduction. This review presents the current knowledge about the methods of lens surgery for the correction of refractive errors in patients with presbyopia and other refractive errors. And also about possible methods of minimization of ultrasound load during the surgery.Purpose. To present current relevant literature scientific knowledge on refractive lens surgery, possible ways of minimization of ultrasound load and new IOL models.Material and methods. To perform the review the literature references were searched through the abstract databases PubMed and Scopus for the period up to and including 2023 using the keywords “zero phaco”, “refractive lens exchange”, “presbyopia”, “femtosecond laser”, “U/S phaco”, “premium IOL”, “refractive error surgery”, “endothelial dystrophy”. A total of 76 articles related to the review topic were selected.Results. Multiple studies confirmed efficacy, safety and fast visual rehabilitation after lens surgery with maximal ultrasound load reduction, in particular in patients with metabolic disorders and predisposition to corneal dystrophies.Conclusion. The literature review suggests that with increasing patient expectations and the use of premium IOLs in the era of refractive lens surgery, predictability and accuracy have become essential. Thus, the technology of safe lens femtosurgery has greatly improved surgical techniques and has revolutionized ophthalmic surgery in recent decades.
Endoscopic Laser Cyclodestruction: Clinical Aspects
Authors: Kulikov A. N. , Skvortsov V. Yu. , Tulin D. V. 
Published: October 2024

Glaucoma is one of the main causes of irreversible vision loss worldwide, its prevalence is increasing with age, reaching 10 % in individuals over 90 years old. Combined surgical treatment of cataract and glaucoma has proven to be safe and effective, reducing overall treatment costs. Minimally invasive glaucoma surgery (MIGS) combined with cataract surgery has become a popular alternative to traditional methods. One such intervention is endoscopic laser cyclodestruction (ELCD), aimed at reducing the production of aqueous humor.Objective: To evaluate the conditions for achieving maximum efficacy and safety of endoscopic laser cyclodestruction (ELCD) in the combined surgical treatment of glaucoma and cataract.Methods. A clinical study was conducted involving 110 patients (56 males and 54 females) with a mean age of 73.7 years, who underwent combined surgery (phacoemulsification + ELCD). Inclusion criteria were stages I-IV glaucoma and initial complicated cataract, while exclusion criteria included lens subluxation and presence of uveal processes or their consequences. ELCD was performed using the Endo Optiks Inc (USA) video-endoscopic ophthalmic laser device. Patients were evaluated preoperatively and followed up at 1, 3, 6, 9, 12, 18, 24, 36, 48, and 60 months postoperatively. The primary safety outcomes included the frequency of intraand postoperative complications, and efficacy outcomes were based on intraocular pressure (IOP) reduction.Results. No hemorrhagic complications were noted. An inflammatory reaction was observed in 18.2% cases, which was managed with subconjunctival injections of prourokinase. The frequency of postoperative IOP elevation correlated negatively with preoperative IOP levels. ELCD demonstrated a statistically significant reduction in IOP and medication burden, with a complete success rate of 52.7 % and a partial success rate of 90.3 %. The extent of cyclodestruction (180–360°) did not significantly affect IOP reduction outcomes.Conclusion. ELCD, performed as part of combined surgery for glaucoma and cataract, proved to be effective and safe, achieving significant IOP reduction and decreasing the need for antiglaucoma medications. Recommendations include avoiding vaporization effects during surgery and preferring patients with preoperative IOP above 27 mm Hg for optimal outcomes.
Efficiency and Safety of the Domestic Device KERATOLINK for the Treatment of Patients with Bacterial Corneal Ulcers
Authors: Seliverstova K. E. , Iomdina E. N. , Yani E. V. 
Published: October 2024

Ultraviolet cross-linking (CXL) of corneal collagen is one of the promising methods for treating bacterial corneal ulcers.Purpose of the work: to evaluate the effectiveness and safety of the use of a new domestic device for corneal CXL KERATOLINK in the treatment of patients with a bacterial corneal ulcer.Materials and methods. Local CXL was performed in 24 patients (24 eyes) aged from 18 to 74 years, who made up the main group. The comparison group included 10 patients of the same age group. To treat ulcerative lesions, drug therapy (antibacterial, corticosteroid, tear replacement and reparative) was used in both groups, but CXL was also used in the main group. The CXL procedure was performed for 5 minutes using the “accelerated cross-linking 2 — ACL 2” program. Each patient underwent 3 procedures with an interval of 2 days. Ophthalmological examination in the main group before treatment, 3 days after the 1st, 2nd and 3rd procedures, as well as 1, 3, 6 months after completion of CXL included visometry, tonometry, microbiological examination of discharge, determination of the size of the defect, optical coherence tomography of the anterior department of the eye (OCT-AS). The comparison group was examined at the same time using the same set of methods.Results. All CXL procedures were completed without complications, no adverse events were identified, and in all cases the recovery period was uneventful. 6 months after CXL, the average uncorrected visual acuity increased from 0.029 ± 0.026 to 0.195 ± 0.175. Already 3 days after the third CXL procedure, there was an absence of microorganisms in the cultures, a significant decrease in the area and depth of the corneal defect (associated with its almost complete epithelization) and a decrease in inflammatory edema according to OCT-АS data. The average period of epithelization of the ulcerative defect was 12 days. Subsequently, stable healing was observed for 6 months, no relapses were detected. In the comparison group, on the 15th day of observation, complete epithelialization was achieved in only 40% of patients.Conclusion. CXL using the KERATOLINK device is a technically simple, minimally invasive method for treating corneal ulcers. A significant reduction in epithelialization time and an increase in visual acuity indicate the effectiveness and safety of the accelerated CXL procedure. The use of an accelerated local CXL protocol with a significant reduction in exposure time helps to increase the comfort and tolerability of the procedure, as well as reduce the risk of complications.
Prevention of Dry Eye Syndrome Before Phacoemulsification of Cataracts in Patients with a History of Cosmetic Procedures in the Periorbital Area
Authors: Trubilin А. V. , Poluninа E. G. , Trubilin V. N. , Zakatianskii V. S. 
Published: October 2024

Phacoemulsification of cataracts in modern ophthalmological practice has reached its peak in terms of safety, predictability of the result and patient satisfaction with the result obtained. The effect of dry eye syndrome on the effectiveness of this surgical intervention has been studied to a large extent, but new risk factors affecting the development of dry eye syndrome arise, such as cosmetic intervention in the periorbital zone (botulinum toxin injections in the periorbital zone, eyelash extensions, blepharoplasty). The effect of these risk factors for the development of dry eye syndrome (DES) on the course of the postoperative period has not been sufficiently studied. An important aspect in preparing patients for ophthalmic surgery, in particular, for phacoemulsification of cataracts, which has moved into the category of, among other things, refractive surgeries, is stabilization of the ocular surface and relief of signs and symptoms of DES.Materials and methods. The study included 117 patients who were planned to undergo phacoemulsification of cataracts. All 117 patients were female for the unification of the study. The first group included 85 people with risk factors for developed dry eye syndrome (botox, tattooing, eyelash extensions, blepharoplasty) in the preoperative period of at least 3 years after cosmetology intervention in the periorbital area. The second control group included 32 patients without risk factors for development in the form of cosmetology intervention in the periorbital area in the preoperative period. The first group was divided into 3 subgroups depending on the type of patient preparation for surgery: 1A (main group) — 30 patients: tear replacement therapy without complex therapy (eyelid hygiene according to the developed technique + massage in the periorbital area), 1B — 29 patients: tear replacement therapy + complex therapy according to the developed technique; 1B — 26 patients: tear replacement therapy + complex therapy according to the standard technique. As the study showed, in the presence of risk factors for the development of dry eye syndrome in the preoperative period before phacoemulsification, including a history of cosmetic interventions in the periorbital area, an increased risk of developing a severe form of dry eye syndrome and an inflammatory process in the early postoperative period was noted at a 2-week observation period. This group of patients is recommended to undergo a set of therapeutic physiotherapeutic procedures — eyelid hygiene + massage in the periorbital area, aimed at restoring the functional activity of the meibomian glands and increasing the stability of the tear film, which reduces the incidence of severe dry eye syndrome and inflammation in the postoperative period after cataract phacoemulsification by 19.89%.
Variability of Antibiotic Concentration in Solutions for Intracameral Administration in Cataract Surgery
Authors: Svetozarskiy S. N. , Igonin G. S. , Starostenko V. V. , Shcherbakova S. V. , Andreev A. N. , Smetankin I. G. 
Published: October 2024

Purpose: to evaluate the variability of cefuroxime concentration for intracameral administration during preparation of ex tempore solutions under conditions of real clinical practice.Materials and methods. Two operating room nurses participated in the study, each prepared 20 samples of cefuroxime solution for intracameral administration according to a uniform dilution protocol. The concentration of antibiotic in the solutions was measured by photocolorimetric method.Results. The experiment modelling the conditions of real clinical practice demonstrated a significant difference of cefuroxime concentrations in solutions prepared ex tempore. The mean antibiotic concentration in samples prepared by 2 nurses was 1.189 [1.075; 1.383] mg/ml and 1.019 [0.984; 1.10] mg/ml, respectively, p = 0.0002. The range of variation was 0.4 mg/ml, or 40.5 % of the minimum recorded value.Conclusion. High variability of cefuroxime concentration during ex tempore preparation may lead to a number of undesirable events. Unintentional overdosing causes the development of serous retinal detachment and anterior chamber toxic syndrome. Low antibiotic content can be considered as one of the reasons for the development of infectious complications caused by cefuroxime-sensitive bacterial strains. Improvement of approaches, substances and routes of administration of antimicrobial agents to improve the safety of cataract surgery in the conditions of changing structure and increasing resistance of ocular microbiota seems to be an urgent scientific task.
Experience of Using Scleral Contact Lenses in Keratoconus in Combination with Dry Eye Syndrome
Authors: Slonimsky A. Yu. , Averich V. V. 
Published: October 2024

Relevance. Currently, a number of numerous publications have proven the comorbidity of keratoconus (CC) with dry eye syndrome (dry eye). The modern method of optical rehabilitation of CC includes scleral rigid gas-permeable lenses (SGCL). In addition to compensating for refractive disorders, this type of lens has increasingly been used in the treatment of SSG, in order to protect the cornea and tear film. Purpose: to assess the change in the state of the precorneal tear film in CC in combination with SSG against the background of wearing SGCL.Patients and methods. 31 patients (62 eyes) with bilateral stabilized non-operated CC of various stages were examined, for whom individual SGCLS were selected. A comprehensive assessment of the condition of the tear film included the following methods: biomicroscopy of the anterior segment of the eye using vital dyes, functional tests (Norn, Schirmer, Jones test), OCT-meniscometry, as well as filling out the OSDI questionnaire by patients and an oral survey on subjective sensations against the background of wearing this type of lenses. The studies were carried out before, after 1 and 3 months on the background of wearing lenses.Results. Prior to the selection of SGCL, an increase in the areas of staining of the ocular surface with vital dyes, a decrease in the results of functional tests and OCT meniscometry, as well as high scores according to the OSDI questionnaire were recorded. After 1 month of wearing lenses, the indicators of all studies showed a tendency to improve the condition of the tear film, and after 3 months there were significant changes relative to the initial data. An oral survey showed full adaptation to the SGCL and wearing comfort in 87 % of cases.Conclusion. A comprehensive assessment of the condition of the tear film in CC in combination with signs of SSG before and against the background of wearing individual SGCL indicates an improvement in the condition of the ocular surface and stabilization of the precorneal tear film, which proves the effectiveness of this type of correction for both optical and protective purposes.
Retinal Map of Peripheral Retinal Degenerations and Tears. Part 2. Non-rhegmatogenous Chorioretinal Degenerations
Authors: Shaimova V. A. , Islamova G. R. , Klyuchko N. A. , Shaimov T. B. , Kuchkildina S. Kh. , Dmukh T. S. , Ivin M. S. , Askaeva A. A. , Kravchenko T. G. , Fomin A. V. 
Published: October 2024

This part of the work describes the results of a multimodal examination of patients with non-rhegmatogenous chorioretinal peripheral degenerations.Objective: to conduct a multimodal study of the vitreoretinal interface of chorioretinal degenerations, to determine their place in the classification of peripheral degenerations to create an informative retinal map of peripheral retinal degenerations.Materials and methods. Patient examinations included traditional and additional ones: the ultrawide-angle fundus imaging with the Clarus 500 or VISUCAM 500 (Carl Zeiss Meditech Inc., Dublin, USA) and wide-field OCT Line scanning using the “sliding method” with SOLIX and RTVue XR Avanti (Optovue Inc. USA).Results. During the period of 2014-2024, 1304 peripheral degenerations and retinal tears were identified through the multimodal examination of 614 patients (959 eyes). Chorioretinal dystrophy was found in 134 patients: paving-stone degeneration — 75 (5.75 %), retinal drusen — 45 (3.45 %), Doyne honeycomb retinal dystrophy — 8 (0.61 %), retinal pigment epithelium hypertrophy (RPE) — 6 (0.46 %). Based on these studies, a clinical and topographic classification of peripheral degenerations and retinal tears is presented.Conclusion. In this article (part 2) we present studies of a group of nonrhegmatogenous chorioretinal degenerations with no changes in the vitreoretinal interface. The multimodal diagnostics of peripheral retinal degenerations have enabled the creation of a retinal map in order to systematize knowledge and improve treatment tactics.
A Case Report of Implantation of the Multifocal Intraocular Lens in a Patient with Marfan’s Syndrome
Authors: Shukhaev S. V. , Petrosyan Yu. M. , Mordovtseva E. A. 
Published: October 2024

Purpose: To demonstrate a case report of successful implantation of multifocal IOL in patients with Marfan syndrome.Materials and methods. A young patient with Marfan’s syndrome asked to the clinic. Examination revealed ectopia of the lens in both eyes. Given his active lifestyle and the desire to get rid of glasses, he was offered surgical treatment with implantation of a multifocal IOL. Lens phacoemulsification was performed with implantation of a modified capsular tension ring, and a trifocal IOL (PanOptix) in the bag.Results. In the late postoperative period, the maximum corrected visual acuity for near in the right eye was 0.9, in the left — 0.8; for the average distance — 0.7 on both eyes; for the distance on the right eye — 1.0, on the left — 0.8.Conclusion. This clinical case demonstrated that in some cases, ectopia of the lens in Marfan syndrome is not a contraindication to the implantation of a multifocal IOL.