bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma Glycated CD59, a Novel Biomarker for Detection of Pregnancy-Induced Glucose Intolerance
Authors: Ghosh Pamela , Luque-Fernandez Miguel A. , Vaidya Anand , Ma Dongdong , Sahoo Rupam , Chorev Michael , Zera Chloe , McElrath Thomas F. , Williams Michelle A. , Seely Ellen W. , Halperin Jose A. 
Published: April 2017

OBJECTIVE
Plasma glycated CD59 (pGCD59) is an emerging biomarker in diabetes. We assessed whether pGCD59 could predict the following: the results of the glucose challenge test (GCT) for screening of gestational diabetes mellitus (GDM) (primary analysis); and the diagnosis of GDM and prevalence of large for gestational age (LGA) newborns (secondary analyses).

RESEARCH DESIGN AND METHODS
Case-control study of 1,000 plasma samples from women receiving standard prenatal care, 500 women having a normal GCT (control subjects) and 500 women with a failed GCT and a subsequent oral glucose tolerance test (case patients).

RESULTS
Compared with control subjects, the median (interquartile range) pGCD59 value was 8.5-fold higher in case patients and 10-fold higher in GDM patients, as follows: control subjects 0.33 (0.19); case patients 2.79 (1.4); GDM patients 3.23 (1.43) (P &lt; 0.001); area under the receiver operating characteristic curve 0.92. LGA prevalence was 4.3% in the lowest quartile and 13.5% in the highest quartile of pGCD59.

CONCLUSIONS
One pGCD59 measurement during weeks 24–28 identifies pregnancy-induced glucose intolerance with high sensitivity and specificity and can potentially identify the risk for LGA.
Does IFRS Convergence Promote the Value Relevance of Accounting Information?
Authors: Kristanto Ari Budi 
Published: April 2017

<p>Penelitian ini bertujuan untuk memperoleh bukti empiris mengenai adanya kandungan informasi, relevansi nilai informasi akuntansi dan pertumbuhannya selama proses konvergensi IFRS di Indonesia. Secara khusus penelitian ini dilakukan pada perusahaan perbankan, asuransi dan pembiayaan yang terdaftar di Bursa Efek Indonesia. Kandungan informasi diindikasikan oleh Trading Volume Activity dan Variability of Abnormal Return. Adapun relevansi nilai informasi akuntansi diproksikan oleh koefisien regresi dari fungsi pengaruh informasi akuntansi terhadap harga saham. Hasil penelitian ini menemukan adanya kandungan informasi serta relevansi nilai informasi akuntansi selama periode konvergensi IFRS. Temuan empiris ini menjadi salah satu indikasi adanya manfaat konvergensi IFRS bagi relevansi nilai informasi akuntansi. Berkaitan dengan konvergensi itu sendiri, penelitian ini menemukan bahwa relevansi nilai informasi akuntansi mengalami peningkatan secara bertahap selama periode konvergensi. Relevansi nilai informasi akuntansi ditemukan pada perusahaan dengan rasio saham diperdagangkan yang tinggi serta perusahaan dengan saham yang tidak likuid. Relevansi nilai yang lebih tinggi juga ditemukan pada perusahaan yang terafiliasi dengan perusahaan dari negara yang mengadopsi IFRS.</p>
Eksplorasi dan Perancangan Prototipe Aplikasi Kantor Maya Untuk Meningkatkan Sustainable Competitive Advantage di Perguruan Tinggi
Authors: Pasharibu Yusepaldo , Sunarto Hari , Sugiarto Agus , Silintowe Yunita Budi Rahayu 
Published: April 2017

<p><em>Sustainable competitive advantage for universities could not be separated from the information technology. Actually, some universities have been implemented this information technology, especially virtual office applications. Eventhough, the virtual office applications were implemented, but preliminary research found that those applications used were Online Transaction Processing only, not Online Analytical Processing that can be used to make decision. Based on those explanations, this research had been done to explore and design the virtual office prototype application for universities. Three methods were used to conduct this reseach, which were explorative, validation, and application design. Finally, prototype applications of virtual office dashboard, lecturer dashboard and accreditation dashboard to improve sustainable competitive advantage for universities were presented as this study result.</em></p>
Memetakan Perubahan Organisasi Dalam Desain Learning Organization Pada Usaha Kecil Menengah di Kota Malang
Authors: Mulyono Sugeng , Kresnaini Enlik 
Published: April 2017

<p><em>This research aims at analyzing the implementation of learning organization at small and medium enterprises (SMEs); the effects of learning organization on individuals’ ability; the effects of individuals’ ability on SMEs changes; and the effects of learning organization on changes of SMEs. The population of this research is all SMEs located in Malang and the samples are 298 SMEs taken through multi stages sampling. The primary data were collected using a questionare and interviews, whereas the secondary were obtain from relevant documents. The collected data were analyzed using descriptive and structural equational modelling (SEM). The results show that learning organization has a significant positive effect on individuals’ ability; the individuals’ ability has a significant positive effect on changes of SMEs; and learning organization has a significant positive effect on changes of SMEs, as indicated by C.R &gt; 2 and value of P &lt; 0,05.</em></p>
Pengembangan Komoditas Batik: Determinasi Budaya Ekonomi dan Perubahan Struktur Kebijakan Terhadap Perkembangan Usaha Ekonomi Lokal (Studi Tentang Pengusaha Batik Laweyan Surakarta)
Authors: Setiawati Erma , Nursiam Nursiam , Zulfikar Zulfikar 
Published: April 2017

<p><em>Batik is an Indonesian national culture product that awarded by UNESCO as world cultural heritage. The research takes place in Kampung Batik Laweyan Surakarta which is the oldest and the center of the traditional batik industry in Indonesia. The purpose of this research is 1) to understand the characteristics of economic culture to look at the social culture of Laweyan Batik business, 2) to explain the development of batik trading which is supported by informal economic opportunities, 3) to analyze the changes in political (policy) structure and its anticipating setrategy. This research is a qualitative research using ethnographic approach. The results showed that 1) batik entrepreneurs in Laweyan characterized as bazaar economy culture with reciprocity social relationships, 2) the business relationship is based on trust, 3) government policy on financial assistance for the development of batik Laweyan plays an important role as anticipation to free trade.</em></p>
Perbedaan Earnings Management Berdasarkan pada Tahapan Life Cycle Perusahaan yang Terdaftar di Bei
Authors: Restuti MI Mitha Dwi , Widyaningrum Luluk 
Published: April 2017

<p><em>This study aimed to find out the differences in the earnings management practice based on the company life cycle (growth , mature ,and stagnant). The samples of this study consists of 224 companies in all sectors except the financial and banking, which were listed in Indonesia Stock Exchange (IDX) during 2010-2012. This study used a Kruskal Wallis test to examine whether there were differences the earnings management practice between each level of the life cycle. The results of the study showed that there were no differences in earnings management practice at each level of the life cycle. Afterward, the earnings management practices between growth and mature level, and between mature, and stagnant level are compared. The result showed that there was a significant difference between the earnings management practice by the companies in the growth and mature level, but there was no significant difference in earnings management practice by the companies in mature</em><br /><em>and stagnant level.</em></p>
Anteseden Dan Konsekuensi Audit Delay Pada Perusahaan Perbankan Perioda 2011-2014
Authors: Tehupuring Ronald , Sitanala Theresia Febiengry 
Published: April 2017

<em>Timeliness in financial reporting can contribute to efficient performance for the stock market because it can reduce the asymmetry information, mitigate insider trading, and improve the usefulness decision of information to stakeholders. There were inconsistencies in prior research and the case of delay submission on issuer financial statements to the Financial Service Authority. There were 30 cases for each in 2013 and 2014. This study aimed to examine (1) the negative impact between the company size, profitability, leverage, and the auditor quality on audit delay; (2) the positive impact of audit delay on audit switching; and (3) the positive impact of audit delay and audit delay switching on audit quality in banking companies listed on the Stock Exchange 2011-2014 period. A purposive sampling method is used and as the sample, 30 companies are obtained in four years so the analyzed data was based on 120 observations. The data analysis technique used is multiple linear and logistic regression. Results showed that (1) the size of the company and leverage have no impact on audit delay, while the return on assets and the auditor quality have a negative impact and significantly related to audit delay; (2) audit delay has a positive impact and significantly related to audit switching; (3) audit delay has a positive impact and significantly related to audit quality, while audit switching has no impact on audit quality. This study has contributed in optimizing timeliness performance of financial information reporting, effectiveness and efficiency of audit time range so that general information increased, and The implication for audit quality of financial statements become more reliable. </em>
Coupled neutronic core and subchannel analysis of nanofluids in VVER-1000 type reactor
Authors: Zarifi E. , Jahanfarnia G. , Sepanloo K. 
Published: April 2017

Abstract
This study is aimed to perform the coupled thermal-hydraulic/neutronic analysis of nanofluids as the coolant in the hot fuel assembly of VVER-1000 reactor core. Water-based nanofluid containing various volume fractions of Al2O3 nanoparticle is analyzed. WIMS and CITATION codes are used for neutronic simulation of the reactor core, calculating neutron flux and thermal power distribution. In the thermal-hydraulic modeling, the porous media approach is used to analyze the thermal behavior of the reactor core and the subchannel analysis is used to calculate the hottest fuel assembly thermal-hydraulic parameters. The derived conservation equations for coolant and conduction heat transfer equation for fuel and clad are discretized by Finite volume method and solved numerically using visual FORTRAN program. Finally the analysis results for nanofluids and pure water are compared together. The achieved results show that at low concentration (0.1 percent volume fraction) alumina is the optimum nanoparticles for normal reactor operation.
Precise Fabrication of Fresnel Flash Lens Featured with V-Grooved Microstructures
Authors: Huang M.-S. , Chen Y.-C. 
Published: April 2017

Abstract
A Fresnel lens is characterized by a micrometer-sized v-grooved structure, and its microstructure quality and curvature accuracy strongly influence its illuminance performance. In this study, a mold is designed for fabricating a Fresnel flash lens involving injection compression molding (ICM). The Taguchi method and parametric analysis are applied to examine the effect of process parameters (mold temperature, melt temperature, injection speed, packing pressure, compression pressure, and time) on the molding quality. Increasing the mold temperature and packing pressure generally improves the polymer melt fill in microsized cavities. ICM enables the realization of v-grooved microstructures with an accurate height replication rate (96.1%) as well as high curvature accuracy (6 μm), creating good optical qualities of the fabricated Fresnel lens with respect to maximum illuminance and illuminance uniformity.
Flow Behavior of PP-Polymer Nanocomposites in Capillary and Injection Molding Dies
Authors: Mitsoulis E. , Battisti M. , Neunhäuserer A. , Perko L. , Friesenbichler W. 
Published: April 2017

Abstract
For simulation of thin-wall injection molding, accurate viscosity data measured at shear rates up to 800,000 s−1 and more are important, but not available in any commercial material database. Such data can be measured on conventional injection molding machines with the help of a rheological mold, which is constructed like a standard injection mold with interchangeable dies. It enables operators to measure viscosity in time on their own machines at practically relevant shear rates (from 102 s−1 to 2 × 106 s−1). A special feature allows measuring the pressure dependency of viscosity using closed-loop counter pressure control. Experimental data are evaluated taking into account the melt temperature rise due to dissipative heating. Using capillary dies having different diameters, D, and length-to-diameter L/D ratios, a full rheological characterization has been carried out for a polypropylene-filled nanocomposite, and the experimental data have been fitted both with a viscous model (Cross) and a viscoelastic one (the Kaye – Bernstein, Kearsley, Zapas/Papanastasiou, Scriven, Macosko or K-BKZ/PSM model). Four injection molding dies have been also used to reach apparent shear rates up to 800,000 s−1. Particular emphasis has been given on the pressure-dependence of viscosity. It was found that only the viscoelastic simulations were capable of reproducing the experimental data well, while any viscous modeling always underestimates the pressures, especially at the higher apparent shear rates and L/D ratios.
A Multifunctional Biocompatible Drug Candidate is Highly Effective in Delaying Pathological Signs of Alzheimer’s Disease in 5XFAD Mice
Authors: Segal-Gavish Hadar , Danino Ortal , Barhum Yael , Ben-Zur Tali , Shai Ella , Varon David , Offen Daniel , Fischer Bilha 
Published: April 2017

Background: Metal-ion-chelation was suggested to prevent zinc and copper ions-induced amyloid-β (Aβ) aggregation and oxidative stress, both implicated in the pathophysiology of Alzheimer’s disease (AD). In a quest for biocompatible metal-ion chelators potentially useful for AD therapy, we previously tested a series of nucleoside 5’-phosphorothioate derivatives as agents for decomposition of Cu(I)/Cu(II)/Zn(II)-Aβ-aggregates, and as inhibitors of OH radicals formation in Cu(I) or Fe(II) /H2O2 solution. Specifically, in our recent study we have identified 2-SMe-ADP(α-S), designated as SAS, as a most promising neuroprotectant. Objective: To further explore SAS ability to protect the brain from Aβ toxicity both in vitro and in vivo. Methods: We evaluated SAS ability to decompose or inhibit the formation of Aβ42-M(II) aggregates, and rescue primary neurons and astrocytes from Aβ42 toxicity. Furthermore, we aimed at exploring the therapeutic effect of SAS on behavioral and cognitive deficits in the 5XFAD mouse model of AD. Results: We found that SAS can rescue primary culture of neurons and astrocytes from Aβ42 toxicity and to inhibit the formation and dissolve Aβ42-Zn(II)/Cu(II) aggregates. Furthermore, we show that SAS treatment can prevent behavioral disinhibition and ameliorate spatial working memory deficits in 5XFAD mice. Notably, the mice were treated at the age of 2 months, before the onset of AD symptoms, for a duration of 2 months, while the effect was demonstrated at the age of 6 months. Conclusion: Our results indicate that SAS has the potential to delay progression of core pathological characteristics of AD in the 5XFAD mouse model.
La consolation par la citation : la lettre de Guittone d'Arezzo à un ami ruiné (Lettre III)
Authors: Le Lay Cécile 
Published: April 2017

La consolation par la citation : la lettre de Guittone d'Arezzo à un ami ruiné (Lettre III)
La lettre III de Guittone d'Arezzo, la plus longue de sa correspondance, est une consolatio adressée à son ami Monte Andrea, poète et banquier, pour l'inviter à voir dans ses déboires financiers le levier pour l'acquisition d'un bien moral. La leçon éthique ainsi impartie est étayée par quelque 160 citations d 'auctoritates, parmi lesquelles, comme on pouvait s'y attendre, Sénèque, cité 30 fois, occupe de loin la première place, suivi par Aristote, dont les 20 citations figurent cependant toutes dans la deuxième partie de la lettre. C'est donc en cours de route, et dans le corps même du texte, qu'Aristote devient le point de repère pour cette concrétisation épistolaire du rapport amical. La lettre constitue ainsi un témoignage important du moment où Guittone accède à la connaissance directe d'Aristote, car ses citations sont, de surcroît, le fruit de sa propre translittération en langue vernaculaire du Compendium latin de l'Ethique à Nicomaque.
Après avoir rappelé la façon dont les artes dictandi venaient de codifier le genre épistolaire, et ce afin d'élucider le contexte rhétorique dans lequel s'insère la correspondance de Guittone, l'article poursuit en illustrant le traitement du thème de l'amitié dans la lettre III. A l'issue de cette analyse, il appert que la lettre à l'ami ruiné constitue un double exploit, à la fois conceptuel et littéraire. Guittone est en effet le premier à rédiger une lettre en langue vernaculaire qui transpose dans le genre épistolaire les modalités propres aux Summae d'inspiration morale (en particulier la Summa de vitiis et la Summa de virtutibus de Guillaume Peyrault [ou Perrault], réunies en en seul volume à partir de 1250) ainsi qu'à la parénèse religieuse des sermones , tout en les associant à la référence directe à Aristote. L'amitié, dont cette lettre est le gage, se veut capable de surmonter les différences sociales ou religieuses entre l'épistolier (le «frate Guittone» qu'il devient après sa «conversion») et le destinataire parce qu'elle s'enracine, comme le veut Aristote, dans la raison, la partie la plus noble de l'esprit humain.
Devotissimus et amicus : l'amitié possible entre le poète et le seigneur
Authors: Ferrara Sabrina 
Published: April 2017

«Devotissimus et amicus» : l'amitié possible
entre le poète et le seigneur dans l'épître XIII de Dante
La réflexion sur 1'«amitié» entre Dante, le poète exilé, et Cangrande Della Scala, le puissant seigneur de Vérone, se structure essentiellement à partir de l'Epître XIII, que le poète envoie au seigneur scaliger en guise de dédicace, et d'accessus, à la troisième cantica de la Comédie. L'amitié entre l'épistolier et le seigneur de Vérone semblerait ne pas pouvoir s'accomplir du fait de la disparité sociale des deux protagonistes, car la vraie amitié procède intrinsèquement d'un rapport de réciprocité (Aristote, Ethique à Nicomaque , Vili, III, 1) et donc d'égalité (Ibidem, Vili, VI, 7). Dante franchit cet obstacle une fois qu'il a pu vérifier, ex visu , les immenses vertus et qualités de Cangrande. Celui-ci est par ailleurs le glorieux protagoniste du chant XVII du Paradis , où a lieu une véritable sublimation du seigneur scaliger et qui constitue l'incontournable glose de l'épître. La nouvelle appréciation de Cangrande détermine, dans l'épître, un glissement sémantique du binôme benevolentia/subiectio au binôme devotio/amicitia , lequel définit alors les axes de l'amitié qui se noue entre le poète et le seigneur.
Les lettres de Lapo Mazzei à Francesco Datini : l'amitié entre le notaire et le grand marchand
Authors: Schuller Michelle 
Published: April 2017

Les lettres de Lapo Mazzei à Francesco Datini : l'amitié entre le notaire et le grand marchand
L'amitié entre le notaire Lapo Mazzei et Francesco Datini, le self made man devenu un richissime homme d'affaires, n'est pas née d'une rencontre de travail, mais de l'impression faite sur le grand marchand par la lecture publique d'une épître du notaire aux Prieurs. S'étant rencontrés peu après, leur amitié a duré jusqu'à la mort de Datini, en 1410.
De l'abondante correspondance (allant de 1390 à 1410) qui permet de retracer l'histoire de l'indéfectible amitié entre ces deux hommes, pourtant séparés par leur statut social, leur mode de vie, leur personnalité, il ne reste que les lettres de Lapo Mazzei, conservées par Francesco Datini, lequel classait et rangeait systématiquement tous les documents qui lui parvenaient.
Dans ce recueil, qui constitue pour nous, par la force des choses, un long monologue épistolaire, les lettres de Lapo Mazzei sont elles-mêmes un discours presque ininterrompu sur l'amitié, dont il ne cesse de reformuler les conditions. En homme cultivé, il illustre son discours de références et de citations, puisant en premier lieu dans les textes sacrés et les écrits des Pères de l'Église, mais citant aussi Dante, bien sûr, et Pétrarque, ainsi que Cicéron, Tite-Live, Horace, Virgile, Sénèque.
On voit alterner deux sortes de lettres : les unes, plutôt courtes, ne concernent que des questions d'ordre pratique ; les autres, beaucoup plus longues, sont nourries de réflexions morales, et constituent souvent de véritables sermons. Lapo, le notaire, prêche littéralement son ami marchand. Sous sa plume, le discours de l'amitié prend donc la forme d'une direction spirituelle, dans laquelle la grande affaire est celle du testament de Francesco Datini. Pressé par son ami, celui-ci finira par léguer la majeure partie de sa fortune à la fondation d'une oeuvre publique de bienfaisance : la Casa e ceppo de poveri di Francesco di Marco, dont le siège abrite aujourd'hui l'Archivio di Stato di Prato et conserve les énormes archives datiniennes.
Métamorphoses du mirabile dans la Cronaca de Salimbene de Adam
Authors: Abbruzzetti Véronique 
Published: April 2017

Metamorfosi del mirabile nella Cronaca di Salimbene de Adam.
Nella Cronaca di Salimbene de Adam, frate francescano del '200 che riferisce fatti svolti tra il 1 168 ed il 1287, si trovano avvenimenti storici, fatti «mirabili», ma anche un trattato sul frate Elia, che permette all'autore di enunciare alcune considerazioni sul «cattivo potere », fatti di cronaca e ritratti di frati francescani e domenicani, ritratti spesso umoristici. A partire da alcuni brani della Cronaca , si analizza il senso di mirabile nel Medioevo e la sua prossimità con il miraculum e si formulano le ipotesi di un mirabile introvabile, di una possibile parabolizza-zione del mirabile per dire infine che il mirabile potrebbe non essere un fatto, un racconto che provoca lo stupore, ma il momento stesso dello stupore.