bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Dosage Regimen on Antihypertensive Medication Compliance
Authors: Keich Ernest W. , Streater James A. , Kennedy Robert J. , Simon Emma T. 
Published: January 2017

Objective: To examine the relationship of the frequency of daily doses and medication compliance for hypertensive patients. Design: Retrospective study, nonrandomized control trial. Setting: Rural, general community. Participants: Convenience sample of 55 outpatients who were prescribed antihypertensive therapy exclusively and whose therapy had been consistent for at least 14 months. Data Extraction: Pharmacy records were accessed to determine the medication compliance of these participants. Main Outcome Measure: Medication compliance differences between participants who were on a once-a-day antihypertensive regimen versus a two-or-more × a day regimen. Results: Patients in the once-a-day regimen group were significantly more compliant than those in the two-or-more × a day group. Conclusions: Consideration must be given to simplification of medication regimens to improve compliance. J Pharm Technol 1994;10:115–7.
Odobromoamide, a Terminal Alkynyl Bromide-Containing Cyclodepsipeptide from the Marine Cyanobacterium Okeania sp.
Authors: Sueyoshi Kosuke , Kudo Takafumi , Yamano Aki , Sumimoto Shimpei , Iwasaki Arihiro , Suenaga Kiyotake , Teruya Toshiaki 
Published: January 2017

Abstract
The bioassay-guided fractionation of the Okinawan marine cyanobacterium Okeania sp. led to the isolation of the novel cyclodepsipeptide odobromoamide (1). The gross structure of 1 was determined by spectroscopic analyses, and its absolute stereochemistry was determined using a variety of different methods, including chemical derivatization and degradation followed by HPLC analysis. In addition, odobromoamide (1) exhibited broad-spectrum cytotoxicity against a human cancer cell line panel.
Para entender o Novo Código de Processo Civil: da dignidade da pessoa humana ao devido processo legal
Authors: Streck Lenio Luiz , Motta Francisco Borges 
Published: January 2017

O presente texto visa a esclarecer e a entender o novo Código de Processo Civil, observando, a partir da dignidade humana, o devido processo legal. Estamos chamando a atenção para o fato de que o novo Código de Processo Civil (Lei n.º 13.105, de 16.3.2015) é, sem dúvida, a primeira grande regulamentação brasileira sobre Processo Civil a ser concebida em um período democrático. Como se sabe, as codificações anteriores foram concebidas em períodos de exceção (1939 e 1973). Partindo dessa premissa, foi dado um belo passo pelo legislador rumo à construção de um modelo democrático de processo. Houve, é certo, mais avanços do que retrocessos. Será demonstrada uma ligação profunda entre dignidade humana e processo democrático conforme estabelece a Constituição do Brasil, em seu art. 5º, LIV, que ninguém será privado de sua liberdade ou bens sem o devido processo legal - como se sabe, a locução devido processo legal corresponde à tradução para o português da expressão inglesa due process of Law - este é o primeiro passo para que nos aproximemos, no contexto do presente trabalho, do tema devido processo legal.
Uma análise conceitual da dignidade como fundamento dos direitos humanos e sua invocação em decisões do STF e da CIDH
Authors: Santos Rafael Seixas , Varella Marcelo Dias 
Published: January 2017

O princípio da dignidade da pessoa humana tem funcionado como fundamento dos Direitos Humanos de modo recorrente em Instituições de relevo nas sociedades democráticas, a exemplo do Supremo Tribunal Federal (STF), no Brasil, e da Corte Interamericana de Direitos Humanos (CIDH). Avaliar como a dignidade pode justificar a aplicação dos Direitos Humanos, inclusive apresentando algumas decisões dessas Cortes, como propõe este texto, contribui para tecer uma fundamentação abrangente a fim de reforçar o emprego da expressão nas diversas esferas sociais. Assim, por meio de uma construção teórica do conceito operacional “dignidade fundamentando Direitos Humanos” e da verificação de seu posicionamento em algumas decisões desses Tribunais, verifica-se a validade e a eficácia do emprego do fundamento. Ainda há amplo campo fértil para o aperfeiçoamento conceitual e para a definição de paradigmas de emprego do fundamento.
Meios autocompositivos de resolução de conflitos coletivos: reflexões sobre a adequação da técnica em favor da efetividade
Authors: Thibau Tereza Cristina Sorice Baracho , Reis Ludmila Costa 
Published: January 2017

O presente artigo propõe-se a analisar as normas que disciplinam os meios autocompositivos de resolução de conflitos no direito brasileiro e confrontá-las com a sua possibilidade de aplicação aos conflitos coletivos. Busca-se problematizar a aplicação das técnicas de conciliação, negociação e mediação às diversas espécies de conflitos, tendo em vista seus traços distintivos. Pretende-se demonstrar que, diante das características inerentes aos conflitos coletivos, impõe-se a busca por soluções técnicas adequadas, sob pena de comprometimento dos resultados consensuais almejados. Assim, apresenta-se a mediação como meio autocompositivo potencialmente adequado para a resolução de conflitos coletivos, desde que seja considerada a necessidade de adequação da técnica às peculiaridades apontadas.
Repensando as fontes do direito na sociedade da informação
Authors: Cunha Paulo Ferreira da 
Published: January 2017

Na linha do que temos vindo a fazer noutros artigos para ramos específicos do Direito e da sua Filosofia (nomeadamente o Penal e o Internacional), o presente artigo recua até aos mais primeiros fundamentos da Teoria do Direito: a questão das fontes. É um rememorar de coisas sabidas e o seu problematizar, depois de muito caminho e experiência percorrida.
Princípio da Ordem Pública no indeferimento de homologação de sentenças arbitrais estrangeiras no Brasil: quando a imprecisão pode levar à desnecessidade
Authors: Ribeiro Gustavo 
Published: January 2017

O artigo enfrenta a aplicação do princípio da ordem pública na homologação da sentença arbitral estrangeira pelo Superior Tribunal de Justiça. O tema é objeto de extenso debate ainda não totalmente consolidado na doutrina e nas cortes. Utilizando-se como marco teórico as concepções delineadas por Jacob Dolinger, desde 1979, indicando a dificuldade e a imprecisão na definição do conteúdo da ordem pública, sugere-se que os indeferimentos dos pedidos de homologação poderiam ter ocorrido sem qualquer alusão à violação à ordem pública. A base da pesquisa consistiu nas sentenças estrangeiras contestadas no período de 2006-2015. Dela, delimitaram-se seis casos cujos pedidos de homologação foram indeferidos pelo Superior Tribunal de Justiça na matéria. Aponta-se que as fundamentações poderiam ter se dado por remissão a critérios objetivos, por exemplo, a ausência de convenção arbitral, a incompetência do juízo arbitral e/ou falta de citação regular de uma das partes - hipóteses previstas na Lei de Arbitragem Brasileira e legislação relacionada. O recurso à ordem pública era desnecessário, embora reflita a complexidade do tema.
Mixed infections in pond fish of Kabardino- Balkarian Republic
Authors: Ахматова  , Akhmatova A. , Житиева  , Zhitieva M. , Казанчев  , Kazanchev M. , Иттиев  , Ittiev A. 
Published: January 2017

The spread and age dynamics of mixed infections in 6 types of fish caused by Trichodina
spp., Trichodinella spp. and other parasites are studied. The method of complete parasitological
autopsy of fish was applied. The differentiation of fish parasites was conducted according to
practice standards. During the examination of 100 fish of various types the following infection
level has been determined: in carp – 52 %, European carp – 46, grass carp – 24, silver carp and
trout – 28, bighead – 14 %. 29,4 % of fish were infected with ecto- and endoparasites. Trichodina
spp. and Trichodinella spp. were detected in 18 % of European carp, 14 % of grass carp, 12 %
of trout, 10 % of silver carp, 8 % of carp, 4 % of bighead. Of the total amount 26,8 % fish were
infected with Trichodina spp., Trichodinella spp., Ichthiophtirius sp. and Dactylorus sp., 31,2 %
– with Trichodina spp., Trichodinella spp., nematodes and cestodes. The infection caused by
Trichodina spp., Trichodinella spp. was increasing with age of the fishes and made in tiny fish 6
%, fingerling fish – 10, 2 years old fish – 20, 3 years old – 30, five years old – 39 % at intensity
of infection 19,2 expl./fish, 28,9; 36,7; 58,8 and 70,5 respectively. Carp fingerlings were infected
with 2–3 species of Trichodina spp., 6 species of Trichodina spp. and Trichodinella spp. were
detected in 3 years old fishes. A high level of infection leads to decreased productivity, condition
factors of fish, technological, commercial and sanitary characteristics of fish production.
Efficacy of the supramolecular complex of Fenbendazole against nematodiasis in sheep
Authors: Скира  , Skira V. , Душкин  , Dushkin A. , Чистяченко  , Chistyachenko Yu. , Халиков  , Khalikov S. , Радионов  , Radionov A. , Белова  , Belova E. , Садова  , Sadova A. , Садов  , Sadov K. , Лимова  , Limova Yu. , Варламова  , Varlamova A. , Архипов  , Arkhipov I. 
Published: January 2017

Objective of research: to study the anthelmintic efficacy of the supramolecular complex of
Fenbendazole used against different nematode species in sheep
Materials and methods: Experiments were carried out on young sheep spontaneously
infected with gastrointestinal strongylates (48 head), Dictyocaulus filaria (42 head), Strongyloides
papillosus (21 head) и Trichocephalus ovis (24 head). In each helminthiasis, the supramolecular
complex of Fenbendazole was given once orally to sheep from various groups at the dose of 3,0;
2,0 and 1,0 mg a.i./kg in comparison with the base preparation Fenbendazole at the doses of 1,0
and 3,0 mg/kg. Sheep which didn’t receive the drug served as controls.
The efficacy of drugs was evaluated before and 18 days after dehelmintization according to the
results of coprolarvoscopic examination by flotation and G. Baermann methods. The registration
of drug activity was performed using the «control test».
Results and discussion: Anthelmintic efficacy was studied and a therapeutic dose for the
supramolecular complex of Fenbendazole produced by chemical mechanical technology using
the Drug Delivery System was determined. In gastrointestinal strongylatoses the supramolecular
complex against D. filaria. at the doses of 3,0; 2,0 and 1,0 mg a.i./kg showed the efficacy of 100;
93,4 and 78% , respectively.
The efficacy of supramolecular complex at the dose of 3,0 mg/kg against S. papillosus was
100 %, and against T. ovis - 98,3 % at 10–13% efficacy of the base preparation Fenbendazole at
the dose of 1,0 mg/kg. The therapeutic dose for the supramolecular complex at main nematodiasis
in sheep was 3,0 mg a.i./kg.
The effectiveness of Albena and Albena in combination with T- and b-activin a in experimental dictyocaulus lambs
Authors: Дегтяревская  , Degtyarevskaya T. 
Published: January 2017

Objective of research. The aim of the research was to investigate the anthelmintic efficiency
of Albena and Albena in combination with T and b-activin a in experimental dictyocaulus lambs.
Materials and methods. Test Albena with 20 % of albendazole and Albena in combination
with T and b-a activin is carried out at the experimental dictyocaulus lambs in August – September
2013 on 18 crossbred lambs aged 4-5 months, free from infection, as confirmed by the results
coprevalence studies by the method of Berman and flotation. Lambs infected with invasive
larvae of Dictyocaulus filaria at a dose of 1000 copies/goal. by providing them with water for oral
administration. In 30 days after infection the lambs were divided into 3 equal groups of 6 animals
each and were kept in machines under conditions that prevent spontaneous infection of lambs.
Lambs of the first group was administered individually orally Albin in the form of 20% of granulated
powder in a dose of 5 mg/kg DW of 0.25 g of granules per 10 kg of body weight. Animals of the
second group asked Albin the same dose and subcutaneously T-activin in a dose of 2 mg/kg
once a day for 1, 3 and 7 days and b-activin in a dose of 5 μg/kg intramuscularly once a day for
5 days. The third group of lambs was used and served as control. The efficacy of the drug was
determined by helminthological autopsy of the lungs of lambs 15 days after deworming.
Results and discussion. Obtained a 100% efficacy of treatment of lambs with Albena in
combination with T and b-activin. Albin at a dose of 5 mg/kg showed 92,3% effective against D.
filaria imaginal. Interenvironment lambs of the control group was 23.5±2,4 EKZ/goal.
The inactivation of helminth eggs with the narrow-bandwidth radiation of excimer lamps
Authors: Липатов  , Lipatov E. , Соснин  , Sosnin Eduard , Авдеев  , Avdeev S. 
Published: January 2017

Objective of research: to study the inactivation of eggs of Opisthorchis felineus and
Diphyllobothrium latum in the water by the narrowband ultraviolet excimer lamp radiation 222 and
282 nm depending on the surface radiation dose.
Materials and methods: Helminth eggs were detected by the Kato technique. The revealed
eggs were flushed into a plastic container with the distilled water and exposed to UV. The
inactivation of eggs was confirmed by the method of optical microscopy.
Results and discussion: It was found that the recovery of helminth eggs from water was 40-
70% more efficient by using UV radiation at 222 nm than at 282 nm.
In addition, the surface radiation dose at 222 nm (up to 5 mJ/cm2) was one order less than at
282 nm (up to 100 mJ/cm2).
Up to 30 % of the initial amount of Opisthorchis felineus eggs were inactivated at 282 nm
surface radiation dose (up to 100 mJ/cm2).
Up to 85 % of the initial quantity of Opisthorchis felineus eggs were inactivated at 222 nm
radiation on the water surface (up to 5 mJ/cm2).
Up to 56 % of Diphyllobothrium latum eggs were inactivated at the comparable 222 nm surface
radiation dose.
Due to the higher photon energy, the more intensive shortwave radiation at 222 nm breaks
shells of Opisthorchis felineus eggs more effectively.
We have a reason to suppose that some features of Diphyllobothrium latum egg shells make
its inactivation at 222 nm less efficient in comparison with the inactivation of Opisthorchis felineus
eggs at the same wavelength of radiation.
The linear growth of roach infected with Ligula Intestinalis plerocercoids in the Chivyrkuysky Bay of the lake Baikal
Authors: Дугаров  , Dugarov Zh. , Ринчинов  , Rinchinov Z. 
Published: January 2017

Objective of research: The purpose of the study is to investigate the influence of Ligula intestinalis plerocercoids on linear growth of roach Rutilus rutilus in the Chivyrkuysky bay of the lake Baikal.
Materials and methods. Roach was caught on a permanent station in the Monakhovo creek of Chivyrkuysky bay of the lake Baikal at the same time interval (June 25-July 5) in 1997-2005. The analysis of roach infection with L. intestinalis plerocercoids was performed based on incomplete parasitological dissections of 807 host specimens at the age of 0+ to 10+. Standard body length (the distance from the tip of the snout to the anterior end of the caudal fin) was used to characterize the linear growth of roach.
Results and discussion. L. intestinalis plerocercoids wasn’t found out in underyearlings (0+) of roach. The host began to be infected with this tapeworm at the age of 1+. The maximum infection level with L. intestinalis plerocercoids was observed in roach at the age of 3+. That one was significantly reduced in the age of 4+. The infection level of roach with L. intestinalis continued to decrease in the next age groups, going down to a minimum at the age of 7+. The roach wasn’t infected with this tapeworm at the age of 8+–10+. A significant reduction of the infection level in the roach in the age classes 4+ and older after the maximum at the age of 3+ was probably associated with parasite-induced mortality of the host during the growth of the age group 3+ to 4+.
A standard body length of roach specimens infected with L. intestinalis at the age of 1+ and 2+ was greater than that of uninfected ones. In contrast, the standard body length of the roach specimens infected with this tapeworm was less than that of uninfected ones in subsequent age classes (3 + -6 +). Differences of standard body length between roach specimens infected with L. intestinalis and uninfected ones were statistically significant in the above-mentioned age groups (1 + 6 +). The effect of L. intestinalis plerocercoids on the linear growth of the roach in Chivyrkuysky Bay of the lake Baikal was manifested in an increase of body length of infected host specimens compared to uninfected ones in young age groups (1+ and 2+) and, vice versa, in one’s decrease in age groups 3+–6 +. We proposed to call this effect “reversive”.
Methodical guidelines for diagnostics, treatment and prevention of canine babesiosis in the central area of the Russian Federation
Authors: Никулина  , Nikulina O. , Новак  , Novak Mikhail , Енгашев  , YEngashyev Syergyey 
Published: January 2017

Objective of research: to study distribution and features of epizootic process at canine babesiosis in the central area of the Russian Federation as well as improvement of diagnostics, treatment and prevention measures.
Materials and methods: Definition of species composition and number of ticks (Ixodidae) on dogs. Statistical analysis of veterinary reports from regional veterinary stations of the Ryazan region. Laboratory microscopic and serological diagnostic test for canine babesiosis.
Results and discussion: Seasonal dynamics of activity of ixodid tick Dermacentor reticulatus (April — June and August — October); maximal extensity of invasion with Babesia spp. (75%); average level of parasitemia in acute and super-sharp form of babesiosis in spring and autumn; clinical parameters of non-sterile immunity in adult and young animals; dependence of the degree of the severity of disease on the age of dogs were determined.
The maximum parasitemia was observed in young (7-23%) and old (6-30%) animals. The average parasitemia was determined in dogs at the age of 3-7 years were 5-11%. The results of hematological and biochemical research revealed that severe acute canine babesiosis is characterized by erythropenia, decreased level of hemoglobin, haematocrit and thrombocytes, leukocytosis, increased level blood bilirubin (by 3-25 times), urea (1,5-5) and creatinine (1,2-3), reduced glucose level (up to 50%).
In babesiosis of light and mild severity, the above-mentioned changes of hematological and biochemical parameters in dogs were not significant. Latent canine babesiosis might be diagnosed by serological test (RAHА) on antibodies to Babesia spp. High efficiency of domestic drugs Babesan (EE = 96,5%), Forticarb (EE = 93,3%), Piro-Stop (EE = 90,9%), Veriben (EE = 82,3%), Neosidin (EE = 75%) for babesiosis in dogs was determined.
The drug Emidonol which has antioxydantic and antihypocsantic properties and was used within 5-7 days for dog treatment, promotes prevention of complications in the form of heart and respiratory failure, and reduction of recovery time. Efficiency of the drug «Bars spot-on» (containing ivermectin) applied against ixodid ticks was detected. Repellent efficiency of the essential oil-based collars «Bar», «Fitodoc» and «Chetyre s hvosticom» used against ixodidosis of dogs, was confirmed, the duration of their action is from 160 to 180 days.
DEVELOPMENT OF NATIONAL SYSTEM OF QUALIFICATIONS IN RUSSIAN FEDERATION: PRACTICE OF APPLICATION OF PROFESSIONAL STANDARDS
Authors: Бутова  , Butova S. , Скачкова  , Skachkova Liudmila , Несоленая  , Nesolenaya O. 
Published: January 2017

Currently, human resources management system in the Russian Federation at the micro and macro levels has serious transformation in connection with the formation
and development of the National Qualifications Framework: professional standards were put in July 2016; national system of assessment of qualifications will start
function in January 2017. The article provides an overview of national qualifications systems, including the European Qualifications Framework. The authors analyze
the causes of the development stages and implementation of professional standards in Russia; present in detail the problems of implementation and use of professional standards in the practice of human resource management of modern organizations.
Expanded Roles for Pharmacy Technicians in the Medication Reconciliation Process: A Qualitative Review
Authors: Irwin Adriane N. , Ham Youngyoon , Gerrity Theresa M. 
Published: January 2017

Background Collection of a complete and accurate medication history is an essential component of the medication reconciliation process. The role of pharmacy technicians in supporting medication reconciliation has been the subject of recent interest. Purpose The purpose of this article is to review the existing literature on pharmacy technician involvement in the medication reconciliation process and to summarize outcomes on the quality and accuracy of pharmacy technician–collected medication histories. Method A literature review was conducted using MEDLINE and Academic Search Premier (1948 – April 2015). Results Sixteen papers were identified, with 12 containing a formal evaluation of outcomes. Three were purely descriptive, and 9 compared the pharmacy technician's performance to pharmacists, nurses, physicians, and/or interdisciplinary teams. Studies used a variety of endpoints, but they demonstrated similar or improved outcomes by engaging pharmacy technicians. Evidence demonstrates that trained pharmacy technicians are able to gather medication histories with similar completeness and accuracy to other health care professionals. Conclusion The use of pharmacy technicians may be a viable strategy for developing and expanding medication reconciliation processes with appropriate supervision. Future efforts should focus on evaluating the impact of expanded roles for pharmacy technicians in the health care system; assessing the need for standardization of pharmacy technician education, training, and certification; and obtaining clarification from state pharmacy boards regarding these expanded roles.