bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased Risk for Adhesive Capsulitis of the Shoulder following Cervical Disc Surgery
Authors: Kang Jiunn-Horng , Lin Herng-Ching , Tsai Ming-Chieh , Chung Shiu-Dong 
Published: May 2016

AbstractShoulder problems are common in patients with a cervical herniated intervertebral disc (HIVD). This study aimed to explore the incidence and risk of shoulder capsulitis/tendonitis following cervical HIVD surgery. We used data from the Taiwan “Longitudinal Health Insurance Database”. We identified all patients who were hospitalized with a diagnosis of displacement of a cervical HIVD and who underwent cervical surgery (n = 1625). We selected 8125 patients who received cervical HIVD conservative therapy only as the comparison group matched with study patients. We individually tracked these sampled patients for 6 months to identify all patients who received a diagnosis of shoulder tendonitis/capsulitis. We found that incidence rates of shoulder tendonitis/capsulitis during the 6-month follow-up period were 3.69 (95% CI: 2.49~5.27) per 100 person-years for the study group and 2.33 (95% CI: 1.89~2.86) per 100 person-years for the comparison group. Cox proportional hazard regressions showed that the adjusted hazard ratio for shoulder tendonitis/capsulitis among patients who underwent cervical disc surgery was 1.66 (95% CI = 1.09~2.53) when compared to comparison group. We concluded that patients who underwent surgery for a cervical HIVD had a significantly higher risk of developing shoulder capsulitis/tendonitis in 6 months follow-up compared to patients who received cervical HIVD conservative therapy only.
Visual processing during natural reading
Authors: Weiss Béla , Knakker Balázs , Vidnyánszky Zoltán 
Published: May 2016

AbstractReading is a unique human ability that plays a pivotal role in the development and functioning of our modern society. However, its neural basis remains poorly understood since previous research was focused on reading words with fixed gaze. Here we developed a methodological framework for single-trial analysis of fixation onset-related EEG activity (FOREA) that enabled us to investigate visual information processing during natural reading. To reveal the effect of reading skills on orthographic processing during natural reading, we measured how altering the configural properties of the written text by modifying inter-letter spacing affects FOREA. We found that orthographic processing is reflected in FOREA in three consecutive time windows (120–175 ms, 230–265 ms, 345–380 ms after fixation onset) and the magnitude of FOREA effects in the two later time intervals showed a close association with the participants’ reading speed: FOREA effects were larger in fast than in slow readers. Furthermore, these expertise-driven configural effects were clearly dissociable from the FOREA signatures of visual perceptual processes engaged to handle the increased crowding (155–220 ms) as a result of decreasing letter spacing. Our findings revealed that with increased reading skills orthographic processing becomes more sensitive to the configural properties of the written text.
TaMCA1, a regulator of cell death, is important for the interaction between wheat and Puccinia striiformis
Authors: Hao Yingbin , Wang Xiaojie , Wang Kang , Li Huayi , Duan Xiaoyuan , Tang Chunlei , Kang Zhensheng 
Published: May 2016

AbstractMetacaspase orthologs are conserved in fungi, protozoa and plants, however, their roles in plant disease resistance are largely unknown. In this study, we identified a Triticum aestivum metacaspase gene, TaMCA1, with three copies located on chromosomes 1A, 1B and 1D. The TaMCA1 protein contained typical structural features of type I metacaspases domains, including an N-terminal pro-domain. Transient expression analyses indicated that TaMCA1 was localized in cytosol and mitochondria. TaMCA1 exhibited no caspase-1 activity in vitro, but was able to inhibit cell death in tobacco and wheat leaves induced by the mouse Bax gene. In addition, the expression level of TaMCA1 was up-regulated following challenge with the Puccinia striiformis f. sp. tritici (Pst). Knockdown of TaMCA1 via virus-induced gene silencing (VIGS) enhanced plant disease resistance to Pst and the accumulation of hydrogen peroxide (H2O2). Further study showed that TaMCA1 decreased yeast cell resistance similar to the function of yeast metacaspase and there was no interaction between TaMCA1 and TaLSD1. Based on these combined results, we speculate that TaMCA1, a regulator of cell death, is important during the compatible interaction of wheat and Pst.
Characterizing dynamic local functional connectivity in the human brain
Authors: Deng Lifu , Sun Junfeng , Cheng Lin , Tong Shanbao 
Published: May 2016

AbstractFunctional connectivity (FC), obtained from functional magnetic resonance imaging (fMRI), brings insights into the functional organization of the brain. Recently, rich and complex behaviour of brain has been revealed by the dynamic fluctuation of FC, which had previously been regarded as confounding ‘noise’. While the dynamics of long-distance, inter-regional FC has been extensively studied, the dynamics of local FC within a few millimetres in space remains largely unexplored. In this study, the local FC was depicted by regional homogeneity (ReHo), and the dynamics of local FC was obtained using sliding windows method. We observed a robust positive correlation between ReHo and its temporal variability, which was shown to be an intrinsic feature of the brain rather than a pure stochastic effect. Furthermore, fluctuation of ReHo was associated with global functional organization: (i) brain regions with higher centrality of inter-regional FC tended to possess higher ReHo variability; (ii) coherence of ReHo fluctuation was higher within brain’s functional modules. Finally, we observed alteration of ReHo variability during a motor task compared with resting-state. Our findings associated the temporal fluctuation of ReHo with brain function, opening up the possibility of dynamic local FC study in the future.
Rapid green assembly of antimicrobial nanobunches
Authors: Byeon Jeong Hoon 
Published: May 2016

AbstractAntimicrobial nanobunches with different amounts of chitosan-capped Ag were prepared by continuous gas-liquid green route under ultrasound irradiation. Spark-produced aerosol Cu nanoparticles were directly injected into an ultrasound Ag(I)-chitosan reaction cell for efficient hydrosolization of the Cu particles and the subsequent incorporation of Ag and chitosan on Cu. Subsequently, electrospraying was used to form of chitosan-capped Cu-Ag nanobunch coatings. The time required for reducing the bacterial proliferation to 50% dropped to ~1 h at a nanobunch concentration of 10 μg mL−1 from the 2.0 min Ag(I) reaction time, and was further decreased to ~0.5 h by increasing the concentration of the nanobunches to 90 μg mL−1. The nanobunches were directly coated onto the substrate using an electrospray device to fabricate transparent films and composite fibers. The antimicrobial activity of the composite carbon fibers was then evaluated via the disc diffusion method.
The Effect of Auditory Information on Patterns of Intrusions and Reductions
Authors: Slis Anneke , van Lieshout Pascal 
Published: May 2016

PurposeThe study investigates whether auditory information affects the nature of intrusion and reduction errors in reiterated speech. These errors are hypothesized to arise as a consequence of autonomous mechanisms to stabilize movement coordination. The specific question addressed is whether this process is affected by auditory information so that it will influence the occurrence of intrusions and reductions.MethodsFifteen speakers produced word pairs with alternating onset consonants and identical rhymes repetitively at a normal and fast speaking rate, in masked and unmasked speech. Movement ranges of the tongue tip, tongue dorsum, and lower lip during onset consonants were retrieved from kinematic data collected with electromagnetic articulography. Reductions and intrusions were defined as statistical outliers from movement range distributions of target and nontarget articulators, respectively.ResultsRegardless of masking condition, the number of intrusions and reductions increased during the course of a trial, suggesting movement stabilization. However, compared with unmasked speech, speakers made fewer intrusions in masked speech. The number of reductions was not significantly affected.ConclusionsMasking of auditory information resulted in fewer intrusions, suggesting that speakers were able to pay closer attention to their articulatory movements. This highlights a possible stabilizing role for proprioceptive information in speech movement coordination.
Using Tag-Return Models to Estimate the Number of Times Fish Are Captured in Fisheries with High Catch-and-Release Rates
Authors: McCormick Joshua L. 
Published: May 2016

Abstract
Exploitation rates are often estimated using tag-return studies. However, in fisheries with a catch-and-release component, exploitation rate or fishing mortality may not be the most important metric of interest. Instead, angler catch rates (e.g., fish caught per hour), total catch (including fish that are harvested or released), or the average number of times an individual fish is caught may be a better measure of fishery performance. However, if anglers remove tags from fish before release, then catch estimates will be negatively biased because tag removal will not be accounted for. In this study, maximum likelihood estimation methods were used to estimate catch in fisheries with high rates of catch and release. Right-censored models were used to accommodate tags that may or may not be removed by anglers. Model-derived maximum likelihood estimates of mean catch were relatively unbiased under two simulated fishery scenarios. There was a nonlinear, positive relationship between the percentage of tags that were removed from fish before release and the standard error of estimated mean catch. Although the models performed well at estimating catch in the simulations, more study is needed to evaluate how possible violation of model assumptions can affect catch estimates.
Received October 19, 2015; accepted February 4, 2016 Published online May 26, 2016
Test-Retest Reliability of the Binaural Interaction Component of the Auditory Brainstem Response
Authors: Ferber Alexander T. , Benichoux Victor , Tollin Daniel J. 
Published: May 2016

Objectives:
The binaural interaction component (BIC) is the residual auditory brainstem response (ABR) obtained after subtracting the sum of monaurally evoked from binaurally evoked ABRs. The DN1 peak—the first negative peak of the BIC—has been postulated to have diagnostic value as a biomarker for binaural hearing abilities. Indeed, not only do DN1 amplitudes depend systematically upon binaural cues to location (interaural time and level differences), but they are also predictive of central hearing deficits in humans. A prominent issue in using BIC measures as a diagnostic biomarker is that DN1 amplitudes not only exhibit considerable variability across subjects, but also within subjects across different measurement sessions.

Design:
In this study, the authors investigate the DN1 amplitude measurement reliability by conducting repeated measurements on different days in eight adult guinea pigs.

Results:
Despite consistent ABR thresholds, ABR and DN1 amplitudes varied between and within subjects across recording sessions. However, the study analysis reveals that DN1 amplitudes varied proportionally with parent monaural ABR amplitudes, suggesting that common experimental factors likely account for the variability in both waveforms. Despite this variability, the authors show that the shape of the dependence between DN1 amplitude and interaural time difference is preserved. The authors then provide a BIC normalization strategy using monaural ABR amplitude that reduces the variability of DN1 peak measurements. Finally, the authors evaluate this normalization strategy in the context of detecting changes of the DN1 amplitude-to-interaural time difference relationship.

Conclusions:
The study results indicate that the BIC measurement variability can be reduced by a factor of two by performing a simple and objective normalization operation. The authors discuss the potential for this normalized BIC measure as a biomarker for binaural hearing.
Photographic Measurements Partially Correlate to Nasal Function and Appearance among Adult Cleft Patients
Authors: Keijser Klara , Nowinski Daniel , Mani Maria 
Published: May 2016

Background:
Unilateral cleft lip and palate (UCLP) affects nasal function and appearance. There is a lack of objective measurements to evaluate these features. This study analyzes whether objective measurements on photographs correlate with nasal function and/or appearance among adults treated for UCLP.

Methods:
All patients with UCLP born from 1960 to 1987 treated at the Uppsala University Hospital were invited (n = 109). Participation rate was 68% (n = 74); mean follow-up was 35 years. An age-matched control group (n = 61) underwent the same tests. Nostril area, nasal tip deviation angle, and width of the nostril were measured on photographs and were compared with functional tests and with appearance as assessed by self-assessment questionnaire, professional panel, or laymen panel.

Results:
The photographically measured nostril area correlated with nasal volume (acoustic rhinometry) among UCLP patients, both cleft side and noncleft side, and controls (0.331, P = 0.005; 0.338, P = 0.004; and 0.420, P < 0.001, respectively). For the patients’ noncleft side and controls, the area correlated inversely with airflow resistance at inspiration (noncleft side: −0.245, P = 0.043; controls: −0.226, P = 0.013). Laymen assessment of nasal appearance correlated with width ratio of the patients (0.27, P = 0.022) and with nasal tip deviation angle and area ratio of the controls (0.26, P = 0.041, and 0.31, P = 0.015, respectively).

Conclusions:
Photographic measurements correlate partially with both functional tests of the nose and panel ratings of appearance. No correlation was found with self-assessment of appearance. Evaluation of photographs needs to be combined with patient-reported outcome measures to be a valuable endpoint of nasal appearance.
Extensive Mine-Shrapnel and Gunshot Wound Closure Using Keystone Island Perforator Flaps
Authors: Sliesarenko Sergii V. , Badiul Pavlo O. , Sliesarenko Kirill S. 
Published: May 2016

Background:
During military operations, one aspect of a plastic surgeon’s work is to restore extensive and deep wound defects in a short period of time and provide a high degree of functional recovery to the damaged area. Because many injuries caused by military operations cannot be closed using a primary suture, the specialist has to select another surgical approach to close the wound defect. Surgeons must select methods that not only cover the extensive wound defect in 1 step but also allow skin coverage that is anatomically, functionally, and visually similar to the surrounding tissues to reduce the length of the hospital stay and ensure optimal functional recovery of the damaged organ.

Methods:
From 2014 to 2015, 25 patients underwent 36 reconstructions at our center after receiving mine-shrapnel and gunshot wounds. All reconstructions occurred during the acute period and used keystone island perforator flaps. The authors’ wound management technique was characterized by an aggressive surgical and antibiotic therapy protocol.

Results:
In all cases, after surgical debridement, the mine-shrapnel and gunshot wound defects were completely closed in 1 stage during the acute period. The working time in the operating room to perform the transposition of the flap ranged from 45 to 90 minutes, with an average of 68 minutes. All displaced flaps were similar in structure and color to the surrounding tissues and did not change the contours of the body. The adequate restoration of skin allowed patients to begin early recovery of functional activity.

Conclusions:
Local keystone island perforator flaps can be considered one of the primary methods of plastic closure of extensive defects caused by mine-shrapnel and gunshot wounds at different anatomical locations, providing that the tissue surrounding the defect is intact and usable as a donor resource.
DIEP Flap for Breast Reconstruction Using Epidural Anesthesia with the Patient Awake
Authors: de la Parra Miguel , Camacho Marco , de la Garza Jonatan 
Published: May 2016

Background:
Many articles have been published about breast reconstruction using the deep inferior epigastric perforator (DIEP) flap; however, few articles have been published in plastic/reconstructive surgery journals describing the difference between anesthetic techniques and recovery in microsurgical patients.

Methods:
We analyzed 16 patients who underwent DIEP flap for breast reconstruction. Patients were divided into 2 groups: group 1: general anesthesia (n = 9); group 2: epidural block with the patient awake (n = 7). In group 2, the peridural block was done at 2 levels: thoracic (T2–T3) and lumbar (L2–L3).

Results:
The success rate was 100% with no partial or total loss of the flap. There was no difference between groups in regard to postoperative pain in the first 5 days (Visual Analog Scale). Analgesia used in group 1 was buprenorphine and ketorolac, and in group 2, only ketorolac without opioid derivatives. Immediate postoperative recovery was better in the peridural group than in the group administered general anesthesia (P = 0.0001).

Conclusions:
DIEP flap with peridural block and the patient awake during surgery is a feasible technique with better recovery in the immediate postoperative period, achieving good analgesia level with minimal intravenous medication.
Case Management Ethics
Authors: Sminkey Patrice V. , LeDoux Jeannie 
Published: May 2016

Purpose:
The purpose of this discussion is to draw attention to the considerable pressure on professional case managers today to coordinate with multiple stakeholders, with responsibilities that put them at the forefront of contact with payers and providers. This discussion raises awareness of how case managers, and board-certified case managers in particular, must demonstrate that they adhere to the highest ethical standards, as codified by the Commission for Case Manager Certification's Code of Professional Conduct for Case Managers.

Primary Practice Settings:
This discussion applies to case management practices and work settings across the full continuum of health care.

Implications for Case Management Practice:
As advocates for clients (individuals receiving case management services) and their families/support systems, case managers must adhere to the highest of ethical and professional standards. The Code of Professional Conduct for Case Managers is an indispensable resource for case managers to ensure that they place the public interest above their own, respect the rights and inherent dignity of clients, maintain objectivity in their relationships with clients, and act with integrity and fidelity with clients and others, as stipulated by the code.
Objective Measures of Pre-lens Tear Film Dynamics versus Visual Responses
Authors: Szczesna-Iskander Dorota H. , Alonso-Caneiro David , Iskander D. Robert 
Published: May 2016

ABSTRACTPurposeTo ascertain whether there is a correlation between objective measures of pre-lens tear film surface quality (TFSQ) dynamics and visual quality responses.MethodsThirty one subjects wore a pair of silicone hydrogel lenses for 1 hour before measurements. Acquisition of TFSQ dynamics was conducted for each subject in suppressed blinking conditions. A Placido disk videokeratoscope was fitted with an internal target and a video streaming output. Subjects were asked to focus on the target and indicate the just noticeable decrease in visual quality. The recorded videos and the subjective responses were saved for further analysis, for which a new videokeratoscopy image processing technique, based on calculating a texture feature (homogeneity), was developed. The estimated times of lens dewetting were then associated with the subjective responses.ResultsThe dewetting point of the lens was identified in 82% of recordings. The group median time of subjective response was 3.5 s post-dewetting point, which corresponded to about 4.3% decrease in TFSQ. In the remaining measurements, either no substantial change in TFSQ or changes related to post-blink slow movement of the lipid layer were observed. The former was not associated with any noticeable change in subjective visual quality whereas the latter usually created visually identifiable temporal disturbance resulting in a subjective response. A small but statistically significant correlation (r2= 0.32, p < 0.001) was found between objectively estimated point of dewetting and the subjective response, corresponding to just noticeable change in visual quality.ConclusionsThe new technique proved to be sufficiently sensitive to identify the distinct two-phase process of pre-lens TFSQ dynamics. Changes in objectively determined pre-lens TFSQ can also be identified subjectively, but there exists, in general, a certain lag between the two responses. The estimated times of lens dewetting could be utilized for in vivo assessment of contact lens wetting parameters.
Effect of Masking on Subjective Responses to Daily Disposable Contact Lenses
Authors: Keir Nancy , Luensmann Doerte , Woods Craig A. , Bergenske Peter , Fahmy Mary , Fonn Desmond 
Published: May 2016

ABSTRACT

Purpose
To explore the effect of masking on subjective responses when wearing daily disposable (DD) contact lenses.

Methods
In an adaptation phase, habitual wearers of Manufacturer-A (MFA) (n = 43) and Manufacturer-B (MFB) (n = 53) wore MFA-brand 1 or MFB-brand 1 DDs, respectively, for 30 days, open-label. Subjects were then randomly assigned to one of two experiments. Each experiment included two, 3-day crossover phases. An enhanced version of MFA and MFB lenses (MFA-brand 2 and MFB-brand 2) were worn contralaterally to evaluate potential differences in masking result between manufacturers. Experiment 1: subjects were fully masked to lens and packaging (FM) then unmasked (UM). Experiment 2: subjects were FM then partially masked using an over-label (PM). Comfort ratings (0–100) were recorded for each lens daily and preference between lenses was recorded on day 3 for each crossover phase. The mean difference between 0–100 ratings or preference when FM or PM versus UM for the same lens was considered a measurement of the effect associated with masking. The purpose of the study was withheld from subjects to minimize bias.

Results
The effect associated with masking for habitual wearers of MFA and MFB lenses was less than 1 out of 100 (0 ± 2.5) in both experiments. Fifty-eight subjects (60%) expressed no preference when FM. This decreased to 29 (30%) when UM or PM (proportion test, p < 0.001). Approximately half the subjects had a change in lens preference when they were UM or PM, primarily in favor of their habitual lens manufacturer.

Conclusions
Masking did not have a measurable impact on 0–100 ratings with the DD lenses used in this study but did have an impact on lens preference. Subjects were more likely to express a preference when they handled the lenses and were exposed to the lens packaging and, in some cases, able to read the lens brand and lens manufacturer.