bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neurodevelopmental Outcomes in Children Vertically Exposed to Chikungunya Virus: A Two Years Follow-up Study
Authors: Quintans Maria D. S. , Vianna Renata A. de O. , Velarde Luis G. C. , de Oliveira Solange A. , Fernandes Alexandre R. , Bueno Arnaldo C. , Cardoso Claudete A. A. 
Published: September 2024

Objectives:
To monitor by the first 24 months of life, children born to mothers with laboratory evidence of chikungunya virus (CHIKV) infection during pregnancy or up to 8 weeks before it, and to describe abnormalities in head circumference (HC), auditory and ophthalmological assessments and neuroimaging tests during the follow-up period.

Method:
This is a observational, descriptive, longitudinal and prospective study of children born to mothers who had a rash and a positive test for CHIKV during pregnancy or up to 8 weeks before it. They were admitted between November 2015 and May 2019 in the outpatient multidisciplinary clinic to investigate acute exanthematous disease. The exposed children were followed up by a multidisciplinary team and underwent periodic measurements of the HC. The Denver II test was applied, in addition to transfontanellar ultrasound (TU) to evaluate neurodevelopmental outcomes during the study period. Ophthalmological and auditory examinations, echocardiography and laboratory tests were also included.

Results:
We included in the study 27 children vertically exposed to CHIKV. All children had a negative polymerase chain reaction test for the virus collected at the first outpatient visit (mean age of 16.8 days and standard deviation of 8 days). No clinical condition compatible with congenital infection at birth was reported. A change in HC characterized by macrocephaly and mild global delay development was observed in a 1-year-old child whose mother was infected in the peripartum, but with normal TU. Changes in the TU were observed in 2 other children with nonspecific subependymal cystic malformation that was not evident by the cranial computed tomography. The other children monitored showed normal results in the Denver II test, in the HC and TU. No changes were identified on ocular ophthalmoscopy or auditory brainstem response test. Two children had an increase in serum ferritin levels during the first year of life, with the others’ inflammatory disease markers normal.

Conclusions:
Our study added knowledge about the neurodevelopment of children exposed to CHIKV during pregnancy by a longitudinal and prospective follow-up, throughout their first 24 months of life. We did not observe a negative impact of exposure to the virus on the neurological examination, global developmental test or measurements of the HC of these children.
Improving Provider Education and Overall Disease Management in Patients With Polycystic Ovarian Syndrome Presenting to a Dermatology Clinic
Authors: Gaudette Laura E. , Codier Louisa , Garcia-Albea Victoria 
Published: September 2024

Aims
The aim of the study was to implement a quality improvement project using the Lean Six Sigma framework of Define, Measure, Analyze, Improve, and Control in an outpatient urban medical dermatology clinic; educate providers about polycystic ovarian syndrome; increase endocrinology referrals; and optimize spironolactone use in these patients ages 12–45 years old.

Background
Patients with polycystic ovarian syndrome experience delays in endocrinology referrals and often suboptimally treated with spironolactone because of lack of provider understanding.

Method
Lean Six Sigma was used to increase provider ability to diagnose and manage polycystic ovarian syndrome, improve spironolactone dosing, and increase endocrinology referral rates through education. Pre-intervention collection occurred July to September 2023. Intervention occurred from September to December 2023. Post-intervention occurred December 2023 to February 2024. Provider surveys were collected through Microsoft Forms, and endocrinology referral rates were collected through the electronic health record, Epic.

Results
Improved provider understanding of polycystic ovarian syndrome was demonstrated in survey results for rate of recognition, confidence, and awareness of diagnostic criteria. Referral rates increased by 90% via SlicerDicer tool within Epic.

Conclusion
Through further education, dermatology providers can improve identification of the polycystic ovarian syndrome, patient outcomes, and patient experience. With identification of the need in this department, there is a platform to incorporate a multidisciplinary clinic.
The effects of health beliefs and acculturation on the acceptance of human papillomavirus vaccination among Asian Indian parents in the United States
Authors: Mullassery Daisy , Posmontier Barabara 
Published: September 2024

ABSTRACT

Background:
The available limited literature and Centers for Disease Control data suggest that human papillomavirus (HPV) vaccination acceptance is lower among Asian Indians than the general population in the United States.

Purpose:
The purpose of the study was to determine the effects of health beliefs, subjective norms, acculturation, and demographics on HPV vaccination acceptance among Asian Indian parents.

Methodology:
Using a comparative descriptive cross-sectional study design, immigrant and first-generation Asian Indian parents of 9- to 16-year-old children were recruited (N = 171). The survey comprised the Health Belief and Subjective Norms instrument and the Suinn-Lew Asian Self-Identity Acculturation Scale. The analysis included parametric and nonparametric tests.

Results:
Participants who expressed higher levels of perceived barriers were less likely to accept HPV vaccination (odds ratio [OR] = 0.47, p = .016). Spousal opinion negatively correlated with HPV vaccination acceptance (OR = 0.57, p = .006). However, subjective norms positively predicted HPV vaccination acceptance (OR = 1.69, p = .039). Participants who perceived that friends and family approved of the vaccination also had significantly higher rates of vaccination acceptance (OR = 11.99, p = .001).

Conclusions:
The results revealed unique factors in the acceptance of HPV vaccination in Asian Indians that were not examined or understood before. The applied Health Beliefs and Subjective Norms theoretical framework suggested that perceived barriers, subjective norms, and the opinions of spouses, friends, and family predicted HPV vaccination acceptance.

Implications:
Educational interventions targeting providers, spouses, family, and community members with influential effects on parents may positively affect HPV vaccination acceptance. Providers should note that this population welcomes the provider's recommendations.
Atypical Primary Sclerosing Cholangitis Findings on a 99mTc-Mebrofenin Scan
Authors: Maharaj Masha , Govender Trisha , Kashala Lusamba , Gounden Strinivasen , Sadhabiriss Dhiren , Chotey Nivesh , Korowlay Nisaar 
Published: September 2024

Abstract
We present an 80-year-old woman with cholestatic liver disease. Ultrasound, CT, and MR cholangiopancreatography showed no substantial findings. The patient was referred for a hepatobiliary scan to examine the physiological pathway of bilirubin and to determine for any level of obstruction. The findings on the hepatobiliary scan suggested intrinsic pathology affecting the entire biliary tree, and histology was recommended. Histology confirmed primary sclerosing cholangitis (PSC). Although hepatobiliary scintigraphy in biliary stasis is well-known and well-published, hepatobiliary scintigraphy in PSC in adults is not well-documented. The hepatobiliary scintigraphy provided the primary and definitive imaging technique in directing the management and diagnosis of PSC in our patient.
The Relationship Between Social Media Use, Nurse Characteristics, and Job Decision-Making
Authors: Nelson-Brantley Heather V. , Parchment Joy , Chipps Esther , Hedenstrom Lisa , Montgomery Aoyjai P. , Ruffin Asiah , Lyman Bret , McHugh Allison 
Published: September 2024

OBJECTIVE
To describe nurses' use of social media and examine the relationship between social media use, nurse characteristics, and job decision-making.

BACKGROUND
Social media shares information, connects, and influences thought. A gap remains in understanding how nurses use social media for professional purposes.

METHODS
A national survey of RNs and advanced practice RNs included demographics, questions about which social media platforms respondents use personally and professionally, and engagement activities on each platform. Data analysis included descriptive statistics, Cramér's V test, and binomial logistic regression.

RESULTS
Eight hundred twelve nurses participated. Platforms and activities used by nurses varied significantly by age, job title, and employment. The majority (61%) of respondents were satisfied or highly satisfied with their job, yet about one-third intended to leave their position or organization within 1 to 12 months.

CONCLUSIONS
Nurse leaders should adopt a strategic, data-informed approach to leverage social media in attracting and retaining a diverse nursing workforce.
Evaluation of the Movement and Play Opportunities and Constraints Associated With Containers for Infants
Authors: Alghamdi Zainab S. , Orlando Julie M. , Lobo Michele A. 
Published: September 2024

Purpose:
Containers (eg, strollers, bouncers) are an important part of infants’ environment but may negatively impact infant development and health. This study evaluated movement and play opportunities, constraints, and manufacturers’ developmental claims for infant containers.

Methods:
Containers were identified through Amazon.com. A content analysis of identified products was conducted to identify movement and visual-manual play opportunities, constraints, and developmental claims.

Results:
Content was analyzed for 460 containers. Containers varied in their movement and play opportunities; however, most did not incorporate toys and restricted trunk movement, self-directed locomotion, and independent head and trunk control. Containers, especially those with built-in toys, often had claims related to gross motor, sensory, and fine motor development.

Conclusion:
These findings demonstrate the variability of movement and play opportunities observed across and within categories of infant containers. General recommendations about container use may be less effective than more specific education to parents about selecting and implementing containers.
Development and Validation of Nosocomial Bacterial Infection Prediction Models for Patients With Systemic Lupus Erythematosus
Authors: Restrepo Escobar Mauricio , Jaimes Barragán Fabián , Vásquez Duque Gloria María , Aguirre Acevedo Daniel Camilo , Peñaranda Parada Édgar Alfonso , Prieto-Alvarado Johana , Mesa-Navas Miguel Antonio , Calle-Botero Estefanía , Arbeláez-Cortés Álvaro , Velásquez-Franco Carlos Jaime , Vergara-Serpa Óscar , Del-Castillo-Gil David Julián , Gordillo-González Camilo Andrés , Guzmán-Naranjo Luis Carlos , Granda-Carvajal Paula Andrea , Jaramillo-Arroyave Daniel , Muñoz-Vahos Carlos Horacio , Vélez-Marín Mariana , Hernández-Zapata Johanna , Eraso-Garnica Ruth , Vanegas-García Adriana Lucía , González-Naranjo Luis Alonso 
Published: September 2024

Background
Hospital-acquired bacterial infections are associated with high morbidity and mortality rates in patients with systemic lupus erythematosus (SLE). This study aimed to develop and validate predictive models for the risk of hospital-acquired bacterial infections in patients with SLE.

Methods
A historical cohort study was designed for development, and another bidirectional cohort study was used for external validation. The risk of bacterial infection was assessed upon admission and after 5 days of hospitalization. Predictor selection employed the least absolute shrinkage and selection operator (LASSO) techniques. Multiple imputations were used to handle missing data. Logistic regression models were applied, and the properties of discrimination, calibration, and decision curve analysis were evaluated.

Results
The development cohort comprised 1686 patients and 237 events (14.1%) from 3 tertiary hospitals. The external validation cohort included 531 patients and 84 infection outcomes (15.8%) from 10 hospital centers in Colombia (secondary and tertiary level). The models applied at admission and after 120 hours of stay exhibited good discrimination (AUC > 0.74). External validation demonstrated good performance among patients from the same tertiary institutions where the models were developed. However, geographic validation at other institutions has been suboptimal.

Conclusions
Two predictive models for nosocomial bacterial infections in patients with SLE are presented. All infection prevention recommendations should be maximized in patients at moderate/high risk. Further validation studies in diverse contexts, as well as clinical impact trials, are necessary before potential applications in research and clinical care.
68Ga-FAPI Response Evaluation Pitfall in a Patient With Esophageal Cancer After Neoadjuvant Therapy
Authors: Liu Huipan , Liu Yuhong , Zhang Jianwen , Chen Yue 
Published: September 2024

Abstract
We report the 68Ga-FAPI PET/CT findings of inflammatory changes and fibrosis in a 55-year-old woman with a history of esophageal cancer after neoadjuvant therapy, which needs to be differentiated from other esophageal diseases during evaluation.
Journal Metrics of the Journal of Craniofacial Surgery: An Analysis Based on the Journal Citation Report 2024
Authors: Tekin Mustafa Said , Durna Yusuf M. , Bahşi İlhan 
Published: September 2024

Objectives:
This study aims the analysis of the journal metrics of Journal of Craniofacial Surgery based on 2024 Journal Citation Reports (JCR) data.

Methods:
In the Journal Citation Reports 2024, shared by Clarivate Analytics on June 20, 2024, the journal metrics of the Journal of Craniofacial Surgery were examined in detail.

Results:
According to the reports published by Clarivate Analytics in 2024, the journal’s impact factor in 2023 was determined as 1.0 and the impact factor excluding self-citations was calculated as 0.8. These values show that the impact factor of the journal has increased in recent years. Also, it is seen that the Journal of Craniofacial Surgery, which has been in the fourth quartile (Q4) among the journals in the “Surgery” category for the last 10 years, has risen to the third quartile (Q3) this year.

Conclusions:
The increase in the impact factor and ranking of the Journal of Craniofacial Surgery shows that the journal has strengthened its position in the scientific field and is moving toward higher levels. However, it is suggested that other metrics should be taken into consideration in addition to the impact factor.
Deep learning detection of dynamic exocytosis events in fluorescence TIRF microscopy
Authors: Lachuer Hugo , Moebel Emmanuel , Macé Anne-Sophie , Masson Arthur , Schauer Kristine , Kervrann Charles 
Published: September 2024

AbstractSegmentation and detection of biological objects in fluorescence microscopy is of paramount importance in cell imaging. Deep learning approaches have recently shown promise to advance, automatize and accelerate analysis. However, most of the interest has been given to the segmentation of static objects of 2D/3D images whereas the segmentation of dynamic processes obtained from time-lapse acquisitions has been less explored. Here we adapted DeepFinder, a U-net originally designed for 3D noisy cryo-electron tomography (cryo-ET) data, for the detection of rare dynamic exocytosis events (termed ExoDeepFinder) observed in temporal series of 2D Total Internal Reflection Fluorescent Microscopy (TIRFM) images. ExoDeepFinder achieved good absolute performances with a relatively small training dataset of 60 cells/∼12000 events. We rigorously compared deep learning performances with unsupervised conventional methods from the literature. ExoDeepFinder outcompeted the tested methods, but also exhibited a greater plasticity to the experimental conditions when tested under drug treatments and after changes in cell line or imaged reporter. This robustness to unseen experimental conditions did not require re-training demonstrating generalization capability of ExoDeepFinder. ExoDeepFinder, as well as the annotated training datasets, were made transparent and available through an open-source software as well as a Napari plugin and can directly be applied to custom user data. The apparent plasticity and performances of ExoDeepFinder to detect dynamic events open new opportunities for future deep-learning guided analysis of dynamic processes in live-cell imaging.
Advertising ultra-processed foods around urban and rural schools in Kenya
Authors: Karugu Caroline H. , Asiki Gershim , Wanjohi Milka , Ojiambo Veronica , Sanya Richard , Laar Amos , Holdsworth Michelle , Vandevijvere Stefanie , Agyemang Charles 
Published: September 2024

AbstractBackgroundMarketing of ultra-processed foods (UPFs) can influence purchase intentions and consumption of such foods, especially among children. There is limited evidence on the extent to which UPFs are marketed around schools in low-and middle-income countries (LMICs), including Kenya. We assessed the extent, content, and type of advertising of ultra-processed/unhealthy foods around schools in urban and rural settings in Kenya.MethodsThis cross-sectional study assessed advertising of food and beverages within a 250m radius around schools in Kenya between June to July 2021. We conducted the study in three counties (Nairobi-urban, Mombasa-coastal urban city, and Baringo-rural). Each county was stratified into high and low socioeconomic status (SES) sub-counties. Within each, we randomly selected schools and collected detailed information on advertising around the schools. The information gathered included the location, type of food and beverage product advertised, and the promotional techniques used. We used the NOVA classification and International Network for Food and Obesity/NCDs Research Monitoring and Action Support (INFORMAS) methods to categorize the food and beverages advertised based on processing level and core (healthy)/non-core(unhealthy) groups. We determined the extent of advertisements using descriptive analysis frequencies, and median (interquartile ranges). Poisson regression was used to determine the factors associated with UPF advertisements.ResultsIn total, 2300 food and beverage advertisements were mapped around the 500 schools. There was a higher median number of advertisements in urban areas (median=25, Interquartile range (IQR)=25,160) compared to rural areas (median=10, IQR= 4, 13). Of these advertisements, approximately 48.0% were UPFs. The most common promotional strategy used was cartoon and company-owned characters, while the most frequent premium offer was price discounts. In the multivariate analysis, there was a significantly higher rate of advertisements of UPFs in Baringo County (prevalence rate ratios (PRR): 1.17, 95% CI: 1.01-1.36) compared to the urban Nairobi County, and in lower compared to higher SES settings (PRR: 1.10, 95% CI: 1.01-1.20).ConclusionUPFs are frequently advertised around schools with promotional strategies that may be appealing to children. There is a need to restrict the marketing of unhealthy foods around schools to children in Kenya.
Co-developing a comprehensive disease policy model with stakeholders: the case of malaria during pregnancy
Authors: Fernandes Silke , Briggs Andrew , Hanson Kara 
Published: September 2024

AbstractIntroductionUnderstanding the holistic impact of malaria during pregnancy is essential for improving maternal and child outcomes in malaria endemic settings. To be able to design appropriate research and conduct robust policy analyses, a comprehensive model of the underlying disease, representing the current understanding of mechanisms and consequences is essential. This study aimed to illustrate a methodology to co-develop a disease model with expert stakeholders using malaria during pregnancy as a case study.MethodsAn initial steering group was convened to develop a first model of malaria during pregnancy and its consequences for mother and child based on their understanding of the literature. Subsequently, this model was refined using a Delphi process to gain consensus amongst twelve experts, representing the disciplines of health economics, mathematical modelling, epidemiology and clinical medicine, working in the field of malaria during pregnancy. Experts reviewed drafts of the conceptual model and provided feedback in two rounds of semi-structured questionnaires with the aim of identifying the most important health outcomes and relationships in both mother and child as well as the most relevant stratifiers for the model. Consensus on any final disagreement was reached after two consensus meetings.ResultsThe final model is a comprehensive disease model of malaria during pregnancy, including ten maternal and ten child outcomes with four stratifiers. The model developed in this study should be of value to malaria researchers, funders, evaluators and decision makers, though some adaptation will be required for each specific context and purpose. In addition, the methodology and process followed in this study is replicable and can guide researchers aiming to develop a conceptual model for other conditions.Discussion & ConclusionThe model resulting from this study highlights the complexity required to depict appropriately the consequences of malaria during pregnancy for both the mother and the child. It also demonstrates how to conduct a rigorous process to develop a disease model. In addition the study has helped to identify a number of areas with scarce data and need for further research.FundingThis study from part of the IMPROVE and IMPROVE-2 studies, which received financial support from the EDCTP2 programme under Horizon 2020 (TRIA.2015-1076, TRIA.2015-1076b); the UK Department of Health and Social Care, the UK Foreign Commonwealth and Development Office, the UK Medical Research Council, and Wellcome Trust, through the Joint Global Health Trials scheme (MR/P006922/1); and the Swedish International Development Cooperation Agency.
Past and present of registered nurse in China--descriptive analysis of longitudinal national statistics of registered nurse
Authors: Yin Lihong , Qiu Liwen , Zhang Guozhou 
Published: September 2024

AbstractBackgroundChina is now in the midst of period of large population aging, which coincides with a global nurse shortage. What added to this problem is the high turnover rate among nurses.MethodsThe longitudinal national statistics of registered nurses were analyzed in order to provide a broad background to understand and interpret the high turnover rate among nurses properly.ResultsA great number of beds, predominantly hospital-based beds, has been hurriedly prepared for potential inpatients in past two decades, and accordingly the increase of medical professionals especially registered nurses. The workload discrepancies of registered nurses among three tiers of hospitals may come from different sources.ConclusionThis discrepancy is helpful in understanding of high nurse burnout and turnover rate though it seems as inherent systematic problems. A trend of high quality medical service attracting more inpatients has shown, this may cause concerns rather than an satisfied answer, were this trend continued.