bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stakeholder Analysis for Adopting a Personal Health Record Standard in Korea
Authors: Kang Min-Jeoung , Jung Chai Young , Kim Soyoun , Boo Yookyung , Lee Yuri , Kim Sundo , Choi Yeonmi , Lee Eui-Kyung , Kim Sukil 
Published: March 2016

Background: Interest in health information exchanges (HIEs) is increasing. Several countries have adopted core health data standards with appropriate strategies. Objective: This study was conducted to determine the feasibility of a continuity of care record (CCR) as the standard for an electronic version of the official transfer note and the HIE in Korean healthcare. Method: A technical review of the CCR standard and analysis of stakeholders' views were undertaken. Transfer notes were reviewed and matched with CCR standard categories. The standard for the Korean coding system was selected. Stakeholder analysis included an online survey of members of the Korean Society of Medical Informatics, a public hearing to derive opinions of consumers, doctors, vendors, academic societies and policy makers about the policy process, and a focus group meeting with EMR vendors to determine which HIE objects were technically applicable. Results: Data objects in the official transfer note form matched CCR standards. Korean Classification of Diseases, Korean Standard Terminology of Medicine, Electronic Data Interchange code (EDI code), Logical Observation Identifiers Names and Codes, and Korean drug codes (KD code) were recommended as the Korean coding standard. ‘Social history’, ‘payers’, and ‘encounters’ were mostly marked as optional or unnecessary sections, and ‘allergies’, ‘alerts’, ‘medication list’, ‘problems/diagnoses’, ‘results’, and ‘procedures’ as mandatory. Unlike the US, ‘social history’ was considered optional and ‘advance directives’ mandatory. At the public hearing there was some objection from the Korean Medical Association to the HIE on legal grounds in terms of intellectual property and patients’ personal information. Other groups showed positive or neutral responses. Focus group members divided CCR data objects into three phases based on predicted adoption time in CCR: (i) immediate adoption; (ii) short-term adoption (‘alerts’, ‘family history’); and (iii) long-term adoption (‘results’, ‘advanced directives’, ‘functional status’, ‘medical equipment’, ‘vital signs’, ‘plan of care’, ‘social history’). Conclusion: There were no technical problems in generating the CCR standard document from EMRs. Matters of concern that arose from study results should be resolved with time and consultation.
A Systematic Literature Review on Security and Privacy of Electronic Health Record Systems: Technical Perspectives
Authors: Rezaeibagha Fatemeh , Win Khin Than , Susilo Willy 
Published: March 2016

Background: Even though many safeguards and policies for electronic health record (EHR) security have been implemented, barriers to the privacy and security protection of EHR systems persist. Objective: This article presents the results of a systematic literature review regarding frequently adopted security and privacy technical features of EHR systems. Method: Our inclusion criteria were full articles that dealt with the security and privacy of technical implementations of EHR systems published in English in peer-reviewed journals and conference proceedings between 1998 and 2013; 55 selected studies were reviewed in detail. We analysed the review results using two International Organization for Standardization (ISO) standards (29100 and 27002) in order to consolidate the study findings. Results: Using this process, we identified 13 features that are essential to security and privacy in EHRs. These included system and application access control, compliance with security requirements, interoperability, integration and sharing, consent and choice mechanism, policies and regulation, applicability and scalability and cryptography techniques. Conclusion: This review highlights the importance of technical features, including mandated access control policies and consent mechanisms, to provide patients' consent, scalability through proper architecture and frameworks, and interoperability of health information systems, to EHR security and privacy requirements.
Rural and Remote Dental Services Shortages: Filling the Gaps through Geo-Spatial Analysis Evidence-Based Targeting
Authors: Shiikha Yulia , Kruger Estie , Tennant Marc 
Published: March 2016

Background: Australia has a significant mal-distribution of its limited dental workforce. Outside the major capital cities, the distribution of accessible dental care is at best patchy. Objective: This study applied geo-spatial analysis technology to locate gaps in dental service accessibility for rural and remote dwelling Australians, in order to test the hypothesis that there are a few key location points in Australia where further dental services could make a significant contribution to ameliorating the immediate shortage crisis. Method: A total of 2,086 dental practices were located in country areas, covering a combined catchment area of 1.84million square kilometers, based on 50 km catchment zones around each clinic. Geo-spatial analysis technology was used to identify gaps in the accessibility of dental services for rural and remote dwelling Australians. An extraction of data was obtained to analyse the integrated geographically-aligned database. Results: Resolution of the lack of dental practices for 74 townships (of greater than 500 residents) across Australia could potentially address access for 104,000 people. An examination of the socio-economic mix found that the majority of the dental practices (84%) are located in areas classified as less disadvantaged. Output from the study provided a cohesive national map that has identified locations that could have health improvement via the targeting of dental services to that location. Conclusion: The study identified potential location sites for dental clinics, to address the current inequity in accessing dental services in rural and remote Australia.
How Suitable Are Registry Data for Recurrence Risk Calculations? Validation of Diagnoses on 1,593 Families With Congenital Heart Disease
Authors: Ellesøe Sabrina Gade , Jensen Anders Boeck , Ängquist Lars Henrik , Hjortdal Vibeke Elisabeth , Larsen Lars Allan , Brunak Søren 
Published: March 2016

Background: Congenital heart disease (CHD) occurs in approximately 1% of all live births, and 3% to 8% of these have until now been considered familial cases, defined as the occurrence of two or more affected individuals in a family. The validity of CHD diagnoses in Danish administrative registry data has only been studied previously in highly selected patient populations. These studies identified high positive predictive values (PPVs) and recurrence risk ratios (RRRs—ratio between probabilities of CHD given family history of CHD and no family history). However, the RRR can be distorted if registry data are used indiscriminately. Here, we investigated the consequences of misclassifications for the RRR using validated diagnoses on Danish patients with familial CHD. Methods: Danish citizens are assigned a civil registration number (CPR number) at birth or immigration, which acts as a unique identifier in the Danish registries, thus enabling connection of information from several registries. Utilizing the CPR number, we identified Danish patients with familial CHD and reviewed each patient’s file. We compared diagnoses from the registries with those manually assigned, which enabled calculation of the PPVs of diagnoses in the Danish registries, and from this, we deduced the false discovery rate (FDR). To measure the consequences on the RRR, the FDR was applied to a simulated data set with true RRR values of 2 and 10. Results: We validated diagnoses of 2,442 patients from 1,593 families. Of these, 874 patients were misclassified corresponding to an FDR of 36%. Applying this FDR on the simulated data sets, we found that the RRR decreased from 2 and 10 to 1.4 and 5.1, respectively. Lastly, we estimated that 11% of all cases with CHD were familial. Conclusion: We found that approximately one of nine of all cases with CHD are familial, and we also found that 36% of individuals with CHD in administrative medical registries are misclassified, which distort the RRR in simulated scenarios.
Testing for association between RNA-Seq and high-dimensional data
Authors: Rauschenberger Armin , Jonker Marianne A. , van de Wiel Mark A. , Menezes Renée X. 
Published: March 2016

Abstract
Background
Testing for association between RNA-Seq and other genomic data is challenging due to high variability of the former and high dimensionality of the latter.

Results
Using the negative binomial distribution and a random-effects model, we develop an omnibus test that overcomes both difficulties. It may be conceptualised as a test of overall significance in regression analysis, where the response variable is overdispersed and the number of explanatory variables exceeds the sample size.

Conclusions
The proposed test can detect genetic and epigenetic alterations that affect gene expression. It can examine complex regulatory mechanisms of gene expression. The R package globalSeq is available from Bioconductor.
Cutaneous stimulation at the ankle: a differential effect on proprioceptive postural control according to the participants' preferred sensory strategy
Authors: Pavailler Sébastien , Hintzy Frédérique , Horvais Nicolas , Forestier Nicolas 
Published: March 2016

AbstractBackgroundAnkle movements can be partially encoded by cutaneous afferents. However, little is known about the central integration of these cutaneous signals, and whether individual differences exist in this integration. The aim of this study was to determine whether the effect of cutaneous stimulation at the ankle would differ depending on the participants' preferred sensory strategy appraised by relative proprioceptive weighting (RPw).MethodsForty‐seven active young individuals free of lower‐limb injury stood on a force platform either barefoot or wearing a custom‐designed bootee. Vibrations (60 Hz, 0.5 mm) were applied either to the peroneal tendons or to the lumbar paraspinal muscles.ResultsThe barefoot RPw was strongly negatively correlated to the absolute change in RPw measured in the bootee condition (r = −0.81, P < 0.001). Participants were then grouped depending on their barefoot RPw value. The RPw was significantly higher in the bootee condition than in the barefoot condition only for participants with low barefoot RPw.ConclusionsThe external cutaneous stimulation given by the bootee increased the weight of ankle proprioceptive signals only for participants with low barefoot RPw. This result confirmed that optimization of the ankle proprioceptive signals provided by cutaneous afferent stimulation has a differential effect depending on the participants' preferred sensory strategy.
Algorithm-guided goal-directed haemodynamic therapy does not improve renal function after major abdominal surgery compared to good standard clinical care: a prospective randomised trial
Authors: Schmid Sebastian , Kapfer Barbara , Heim Markus , Bogdanski Ralph , Anetsberger Aida , Blobner Manfred , Jungwirth Bettina 
Published: March 2016

Abstract
Background
Acute kidney injury is a common complication after major surgery. In this study, we investigated whether an algorithm-guided goal-directed haemodynamic therapy (GDT) can improve renal outcome compared to good standard clinical care.

Methods
A total of 180 patients undergoing major abdominal surgery were prospectively and randomly assigned to one of two groups: in the GDT group, patients were treated with a GDT algorithm using transpulmonary thermodilution while standard care was applied to the control patients. Change in creatinine was studied as the primary end point, postoperative complications as well as 1-year mortality as secondary outcomes. Haemodynamics in GDT and control patients were compared calculating goal-achievement rates.

Results
Postoperative change in creatinine (18 ± 39 μmol/l (control) vs. 16 ± 42 μmol/l (GDT); mean difference (95 % confidence interval) 1.6 μmol/l (−10 to 13 μmol/l)) was comparable between the GDT and the control group. Postoperative complications and mortality during hospital stay and after 1 year were not influenced by the use of a GDT algorithm. Achievement rates of haemodynamic goals were not higher in the GDT group compared to the already high (>80 %) rates in the control group. Multivariate regression analysis revealed intraoperative hypotension (MAP < 70 mmHg) and postoperative hypovolaemia (GEDI < 640 ml/m2) as risk factors for postoperative renal impairment.

Conclusions
In this study, GDT was not superior to standard clinical care in order to avoid renal failure after major abdominal surgery. The reason for this finding is most likely the high achievement rate of haemodynamic goals in the control group, which cannot be improved by the GDT algorithm.

Trial registration
Clinicaltrials.gov; NCT01035541; registered 17 December 2009.
Convergence theorems for finite families of total asymptotically nonexpansive mappings in hyperbolic spaces
Authors: Ali Bashir 
Published: March 2016

AbstractIn this paper, using a multistep iterative scheme, we establish strong and Δ-convergence theorems for finite families of total asymptotically quasi-nonexpansive mappings in uniformly convex hyperbolic spaces. We then establish Δ- and polar convergence theorems for finite families of total asymptotically nonexpansive mappings in CAT(0) spaces. These new theorems are extensions, improvements, and generalizations of some recently announced results by many authors.
Post-hatching development of mitochondrial function, organ mass and metabolic rate in two ectotherms, the American alligator (Alligator mississippiensis) and the common snapping turtle (Chelydra serpentina)
Authors: Sirsat Sarah K. G. , Sirsat Tushar S. , Price Edwin R. , Dzialowski Edward M. 
Published: March 2016

ABSTRACTThe ontogeny of endothermy in birds is associated with disproportionate growth of thermogenic organs and increased mitochondrial oxidative capacity. However, no similar study has been made of the development of these traits in ectotherms. For comparison, we therefore investigated the metabolism, growth and muscle mitochondrial function in hatchlings of a turtle and a crocodilian, two ectotherms that never develop endothermy. Metabolic rate did not increase substantially in either species by 30 days post-hatching. Yolk-free body mass and heart mass did not change through 30 days in alligators and heart mass was a constant proportion of body mass, even after 1 year. Yolk-free body mass and liver mass grew 36% and 27%, respectively, in turtles during the first 30 days post-hatch. The mass-specific oxidative phosphorylation capacity of mitochondria, assessed using permeabilized muscle fibers, increased by a non-significant 47% in alligator thigh and a non-significant 50% in turtle thigh over 30 days, but did not increase in the heart. This developmental trajectory of mitochondrial function is slower and shallower than that previously observed in ducks, which demonstrate a 90% increase in mass-specific oxidative phosphorylation capacity in thigh muscles over just a few days, a 60% increase in mass-specific oxidative phosphorylation capacity of the heart over a few days, and disproportionate growth of the heart and other organs. Our data thus support the hypothesis that these developmental changes in ducks represent mechanistic drivers for attaining endothermy.
Response Letter to Editor: In response to The Letter to Editor by Dinçer (2016): Concerning “A content analysis and methodological evaluation of meta-analyses on Turkish samples”<p>"Türkiye örnekleminde meta analiz çalışmalarının içerik analizi ve metodolojik değerlendirilmesi" konusunda Dinçer (2016) "Editöre Mektup"a cevaben
Authors: Başol Gülşah 
Published: March 2016

This letter was written in response to Dinçer (2016)’s letter in response to Başol, Doğuyurt and Demir (2016), published in the recent edition of International Journal of Human Sciences. First, the model selection approach followed in the studies by leading author were explained in detail, in order to make it clear that the model selection was not based on a statistical test as it was claimed in Dinçer’s letter. The second part of the letter includes an explanation to the ethical concerns in the letter. ÖzetBu mektup, Uluslararası İnsan Bilimleri süreli yayınında yayımlanan Dinçer’e (2016) ait, Başol, Doğuyurt and Demir (2016) çalışmasına cevaben yazılmış olan editöre mektuba cevap niteliğindedir. Mektubun birinci bölümünde, Dinçer (2016)'da belirtilen, tarafımın dahil olduğu meta analiz çalışmalarında model seçiminde izlenilen yol açıklanmış; Dinçer (2016)'da bahsi geçtiği üzere hetorojenlik testine bağlı olarak model seçiminin çalışmalarımda söz konusu olmadığı ortaya konmuştur. Mektubun ikinci bölümünde, Dinçer (2016)’da dile getirilen etik kaygılara cevap verilmiştir.
On the Inf-Sup Constant of a Triangular Spectral Method for the Stokes Equations
Authors: Su Yanhui , Chen Lizhen , Li Xianjuan , Xu Chuanju 
Published: March 2016

Abstract
The Ladyženskaja–Babuška–Brezzi (LBB) condition is a necessary condition
for the well-posedness of discrete saddle point problems stemming from discretizing
the Stokes equations. In this paper, we prove the LBB condition and provide the (optimal) lower bound for this condition for the triangular spectral method proposed by L. Chen, J. Shen, and C. Xu in [3]. Then this lower bound is used to derive an error
estimate for the pressure. Some numerical examples are provided to confirm the theoretical estimates.
Performance Investigation of Membrane Process in Natural Gas sweeting by Membrane Process: Modeling Study
Authors: Ghasemzadeh Kamran , Jafari Mostafa , sari Amir , Babalou Ali A. 
Published: March 2016

Abstract
The main purpose of this work is the numerical investigation of PEBX membrane performance for natural gas sweeting. Hence, a single-stage process for PEBX membrane was considered in various flow patterns, namely, cocurrent, cross flow and countercurrent to separate a typical natural gas mixture. To this target, a black box numerical model was extended for the ASPEN HYSYS commercial package and also its validation was realized by litterature experimental data. The validation results indicated a good agreement between thoritical results and experimental data. After model validation, the effect of the some significant operating parameters (pressure gradient, stage cut and membrane area) on the performance of PEBX membrane was analysed in terms of acid gases removal percentage. The simulation results presented a noticeable performance of PEBX membrane to produce high purity CH4. In particular, concerning the stage cut effect, it was found that the CO2 and H2S compositions in the permeate side were decreased through the enhancment of stage cut from 0.005 to 0.03, whereas the CH4 composition increased for whole the flow patterns. Moreover, a similar effect was achived for membrane surface area. On the other hand, the transmembrane pressure effect was positive on the PEBX membrane performance during natural gas sweeting.
An analytical study of the endoreversible Curzon–Ahlborn cycle for a non-linear heat transfer law
Authors: Páez-Hernández Ricardo T. , Portillo-Díaz Pedro , Ladino-Luna Delfino , Ramírez-Rojas Alejandro , Pacheco-Paez Juan C. 
Published: March 2016

Abstract
In the present article,
an endoreversible Curzon–Ahlborn engine is studied by considering a non-linear heat transfer law, particularly the Dulong–Petit heat transfer law, using the `componendo and dividendo' rule as well as a simple differentiation to obtain the Curzon–Ahlborn efficiency as proposed by Agrawal in 2009. This rule is actually a change of variable that simplifies a two-variable problem to a one-variable problem. From elemental calculus, we obtain an analytical expression of efficiency and the power output. The efficiency is given only in terms of the temperatures of the reservoirs, such as both Carnot and Curzon–Ahlborn cycles. We make a comparison between efficiencies measured in real power plants and theoretical values from analytical expressions obtained in this article and others found in literature from several other authors. This comparison shows that the theoretical values of efficiency are close to real efficiency, and in some cases, they are exactly the same. Therefore, we can say that the Agrawal method is good in calculating thermal engine efficiencies approximately.
Assessment of selected health behaviors of women after breast cancer therapy
Authors: Prokopowicz Katarzyna , Prokopowicz Grzegorz , Molik Bartosz , Kozdroń Ewa 
Published: March 2016

Abstract
Introduction: Health is highly valued by individuals as well as whole social groups. Lifestyle, and related with this health behaviors are believed to be the main factors that largely determine its condition. Poland is a country, where the number of malignant cancer morbidity is systematically increasing. Breast cancer is the most common among women aged 45 years old. Despite the relative stability of the mortality outcomes the rate of it is still high. This situation is influenced by many factors, including the limited awareness of the value of health-related behaviors.
Material and methods: The study included 70 women aged 45-75 years old. The study and control group consisted of: 36 women with breast cancer and 34 women without cancer in history. The specifically developed questionnaire and the Positive Health Behaviors Scale for Women developed by Hildt-Ciupińska were used in this study. IBM SPSS v. 21.0 was used for statistical analysis and non-parametric U-Mann Whitney test.
Results: The study let determine the level of women's health behaviors. The analysis of the results showed that there are much anomalies in health-related behaviors in both studied groups. The lowest point scale values were reported in the "Physical activity" subscale. The highest values were reported in the "Safety behaviors" and "Caring body" subscale. The disappointing results in statements related with the prevention of cancer were the most alarmous.
Conclusions: The introduction of health prevention awareness programs in the group of women over 45 years of age, may contribute to an increase in the frequency of health-promoting behaviors.
Life cycle assessment of dairy farms
Authors: Taufiq Fierly Muhammad , Padmi Tri , Rahardyan dan Benno 
Published: March 2016

Abstract
In 2013 the population of dairy cattle in Indonesia had reached 636,000 head with a 4.61% growth rate per year. The inputs were energy, water, and feed. These inputs produced outputs, such as emissions, solid waste and liquid waste. This research compared the maintenance systems in modern farms and local farms. The data were collected from 30 local farmers and one modern farm. This research used the life cycle assessment (LCA) method. LCA is based on ISO 14040. LCA consists of several stages: the goal and scope definition, inventory analysis, impact assessment, and interpretation. This research used the cradle to gate concept and fat corrected milk (FCM) as the function unit. The impacts of these activities could generate global warming potential (GWP), acidification potential (AP), and eutrophication potential (EP). The calculations showed that the systems in local farms had the greatest emissions result over all impacts. In the case of local farms, the GWP was 2.34 kg CO2 eq/L of milk FCM, AP was 0.12 g SO2 eq/L of milk FCM, and EP was 18.28 g

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eq/L milk FCM. While the impact from the modern farm was GWP of 1.52 kg CO2 eq/L of milk FCM, AP of 0.02 g SO2 eq/L of milk FCM, and EP of 0.353 g

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eq/L of milk FCM. Based on the total-weighted result, the GWP had the greatest impact from the overall life cycle phase of milk production. The total-weighted result obtained was of 0.298 EUR/L of FCM from a local farm and 0.189 EUR/L of FCM from the modern farm. This amount could be used to remediate the global warming, acidification, and eutrophication impacts of milk production.