bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tuning the Nucleophilicity of Anion in Lithium Salt to Enable an Anion‐Rich Solvation Sheath for Stable Lithium Metal Batteries
Authors: Zhou Pan , Ou Yu , Feng Qingqing , Xia Yingchun , Zhou Haiyu , Hou Wen‐hui , Song Xuan , Lu Yang , Yan Shuaishuai , Zhang Weili , He Yun , Liu Kai 
Published: October 2024

AbstractTraditional lithium salts typically adhere to the designing principles of enhancing cation‐anion dissociation degree to obtain a high electrolyte conductivity. This promotes the invention of lithium bis(trifluoromethanesulfonyl)imide (LiTFSI), where the symmetric electron‐withdrawing trifluoromethanesulfonyl groups significantly delocalize the negative charge density around the nitrogen atom, thereby weakening the electrostatic interaction between Li+ and the anion. Herein, deviating from the general principle, lithium (methanesulfonyl)(trifluoromethanesulfonyl) imide (LiMTFSI) is deliberately designed by substituting a unilateral electron‐withdrawing trifluoromethyl (─CF3) group of LiTFSI with an electron‐donating methyl (─CH3) group, to tune the nucleophilicity of the anion. This modification enhances Li‐anion interaction, causing the anion to replace the solvent molecules in the Li+ solvation shell. Additionally, the MTFSI− anion exhibits an elevated donor number to facilitate the solubility of LiNO3 in carbonate‐based electrolytes. The synergistic effect of these changes suppresses the decomposition of solvent and helps construct a stable solid electrolyte interphase (SEI) enriched with multiple inorganic lithium salts (e.g., Li2S, Li3N, and LiNxOy) on the Li metal anode, which enables the 500 mAh Li||LiNi0.5Co0.2Mn0.3O2 pouch cell to operate steadily for 150 cycles. It is believed this work would provide new insights and another dimension for designing functional anions beyond their role as charge carriers.
Stable Droplet Manipulation in Multiple Directions on a Magnetically Responsive Micropillar Array Surface
Authors: Liu Xinyuan , Jia Li , Ding Yi , Dang Chao , Yin Liaofei , Xu Jinzhu , Zhang Ruiqi 
Published: October 2024

AbstractDroplets constitute an essential discrete form of liquids and are prevalent in both natural and industrial fields. Droplet manipulation technologies have broad application prospects in various fields, including biomedical devices, chemical engineering, water collection, and so on. The manipulation of surfaces with magnetic responsiveness has emerged as a pivotal technique in droplet control owing to its flexibility and precision in remote operations. In this study, the dynamic rolling behavior of low‐surface‐tension working fluids and water droplets on a superhydrophobic magnetically responsive micropillar array (SMMA) is investigated, with a focus on the mechanisms that generate instabilities during the directional rolling motion of droplets. The factors influencing these instabilities are studied using data analysis. Moreover, techniques for capturing and releasing droplets are investigated, offering significant insights into the efficient handling of minute amounts of liquids in experiments and the automation of intricate chemical processes.
Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects
Authors: Chen Yuanchun , Shangguan Shijie , Lin Zhongyu , Zeng Xuemei , Chan Siew Yin , Qin Xian , Yan Shuangqian 
Published: October 2024

AbstractX‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical tumor treatment through radiotherapy. Despite their widespread use, optimizing X‐ray efficacy remains a critical challenge due to issues such as radiation resistance and damage to surrounding health tissues. Recent advancements in nanotechnology have introduced new opportunities and challenges in cancer diagnosis and treatment. This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. We examine how nanomaterials, including metals, metal oxides, metal sulfides, metal fluorides, rare earth oxides, cluster compounds, metal‐organic frameworks, and nanohybrids, enhance the effectiveness of X‐ray‐triggered treatments. Furthermore, we address the current challenges and future prospects of efficient X‐ray‐triggered cancer therapy, aiming to provide a comprehensive overview for researchers and clinicians in the field.
Mathematical modelling, energy consumption, and quality evaluation of wheat seeds subjected to intermittent drying
Authors: Aranha Ana Caroline Raimundini , Defendi Rafael Oliveira , Suzuki Rúbia Michele , Júnior Oscar de Oliveira Santos , Madrona Grasiele Scaramal , Ferrari Andressa Lopes , Matias Gustavo de Souza , Mogollón Emerson Barrios , Molinari Deise , Ferreira Cintia Stefhany Ripke , Jorge Luiz Mario de Matos 
Published: October 2024

AbstractThis work aims to evaluate the kinetic profile of intermittent drying of wheat seeds using traditional models from the literature and the fractional calculus technique. Furthermore, it aims to verify the application of the intermittent drying process on the amount of antioxidant compounds, protein, and lipid content of the grain, in addition to energy consumption to obtain the desired final moisture content of the wheat. It was verified that the prediction of drying kinetics by Page and fraction order models were similar (modelling efficiency varying between the range of 0.917–0.995, varying the drying condition and wheat cultivar). Regarding antioxidant compounds for the three wheat cultivars, it can be seen that the higher fraction of ethanol (74.0% and 90.36%) used for extraction had greater process efficiency. Regarding the protein content in the three wheat cultivars, lower drying temperatures and intermittency periods result in lower quality losses of material (12.3% for BRS‐Atobá wheat, 9.89% for BRS‐Jacana wheat, and 18.71% for BRS‐Sanhaço wheat). In terms of lipids, it was found that the influence of temperature was greater on the lipid content than on the protein content of the material (for the best drying condition, there were percentage decreases for the best condition of 36.16% for the BRS‐Atobá wheat, 34.9% for BRS‐Jacana, and 52.2% for BRS‐Sanhaço). Regarding energy consumption during the drying process, it can be seen that the conditions used for intermittency and drying time, in addition to the sample conditions, directly impact energy consumption.
Inhibiting lncRNA NEAT1 Increases Glioblastoma Response to TMZ by Reducing Connexin 43 Expression
Authors: Liang Jinxing , Xie Jia‐xiu , He Junhui , Li Yi , Wei Dongmei , Zhou Rongfei , Wei Guining , Liu Xuehua , Chen Qiudan , Li Dongmei 
Published: October 2024

ABSTRACTObjectivesGlioblastoma multiforme (GBM) is considered the most assailant subtype of gliomas, presenting a formidable obstacle because of its inherent resistance to temozolomide (TMZ). This study aimed to characterize the function of lncRNA NEAT1 in facilitating the advancement of gliomas.MethodsThe expression level of NEAT1 in glioma tissues and cells was detected by qRT‐PCR. RNA interference experiment, cell proliferation assay, FITC/PI detection assay, immunoblotting, bioinformatics prediction, a double luciferase reporter gene assay, RNA immunoprecipitation (RIP) assay, SLDT assay and correlation analysis of clinical samples were performed to explore the regulatory effects of NEAT1, miR‐454‐3p and Cx43 and their role in malignant progression of GBM. The role of NEAT1 in vivo was investigated by an intracranial tumor formation experiment in mice.ResultsThe results showed that recurring gliomas displayed elevated levels of NEAT1 compared to primary gliomas. The suppression of NEAT1 led to a restoration of sensitivity in GBM cells to TMZ. NEAT1 functioned as a competitive endogenous RNA against miR‐454‐3p. Connexin 43 was identified as a miR‐454‐3p target. NEAT1 was found to regulate gap junctional intercellular communication by modulating Connexin 43, thereby impacting the response of GBM cells to TMZ chemotherapy. Downregulation of NEAT1 resulted in enhanced chemosensitivity to TMZ and extended the survival of mice.ConclusionsOverall, these results indicated that the NEAT1/miR‐454‐3p/Connexin 43 pathway influences GBM cell response to TMZ and could offer a potential new strategy for treating GBM.
Applicability of heart failure clinical practice guidelines in low‐ and middle‐income countries
Authors: Zieroth Shelley , Giraldo Clara Inés Saldarriaga , Pinto Fausto , Anker Stefan D. , Abraham William T. , Atherton John J. , Butler Javed , Chopra Vijay , Coats Andrew J.S. , Dean Veronica , Filippatos Gerasimos , Zamorano Jose Luis , Zhang Yuhui , Weiskopf Richard B. , Colardelle Yann 
Published: October 2024

AbstractAimsClinical practice guidelines are commonly written by professional societies in high‐income countries (HIC) with limited anticipation of implementation obstacles in other environments. We used heart failure (HF) guidelines as a paradigm to examine this concern, by conducting a survey to understand clinicians' ability to implement HF guidelines and their perceptions of the current HF guideline applicability in low‐ and middle‐income countries (LMIC).Methods and resultsAn online survey of physicians in the database of the Translational Medicine Academy who treat HF patients was offered by email from 5 October to 27 November 2023, inquiring of participants' demographic information, experience, and views of HF guidelines as related to their practice. Of 2622 participating clinicians, 1592 partially completed, and an additional 1030 fully completed the survey. Participants were from 138 countries; 668 practiced in HIC, and 1954 in LMIC. Those from LMIC regarded HF guidelines to be less applicable in their country than did those from HIC (p = 0.0002). Of all those responding, 75.3% indicated that it was somewhat or mostly true that the HF guidelines were mostly applicable to HIC. Those from LMIC, but not HIC indicated that the greatest implementation obstacle was that the guidelines were for HIC (51.3% vs. 43.1%; p = 0.0387). A significantly higher proportion of respondents from LMIC indicated that resources for caring for their patients were somewhat or mostly limiting in most cases, than did those in HIC (41.6% vs. 32.5%, p = 0.0068).ConclusionThis survey examined the widely‐held thought that HF guidelines are broadly applicable to all regions of the world, concluding that such a perception is incorrect. Clinicians from LMIC view the absence of consideration of local resource limitations as the greatest obstacle for guideline implementation. The results regarding HF guidelines likely also have implications for other guidelines and resultant patient outcomes.
Fetal Face: Enhancing 3D Ultrasound Imaging by Postprocessing With AI Applications: Myth, Reality, or Legal Concerns?
Authors: Tonni G. , Grisolia G. , Tonni Silvia , Lacerda Valter Andrade , Ruano Rodrigo , Sepulveda Waldo 
Published: October 2024

ABSTRACTThe use of artificial intelligence (AI) platforms is revolutionizing the performance in managing metadata and big data. Medicine is another field where AI is spreading. However, this technological advancement is not amenable to errors or fraudulent misconducts. International organization and recently the European Union have released principles and recommendations for an appropriate use of AI in healthcare. In prenatal ultrasound diagnosis, the use of AI in daily practice is having a revolutionary impact. Notwithstanding, the diagnostic enhancement should be regulated, and AI applications should be developed to guarantee correct imaging acquisition and further postprocessing.
Bridging Frontiers in Macromolecular and Supramolecular Sciences with Living Cationic Ring‐Opening Polymerization of Self‐Organizable Dendronized Cyclic‐Imino Ethers Generating Soft Frank–Kasper and Quasicrystal Arrays
Authors: Percec Virgil , Sahoo Dipankar 
Published: October 2024

AbstractLiving cationic ring‐opening polymerization accompanied by isomerization of cyclic imino ethers is performed at high temperatures that provide access to the synthesis of self‐organizable systems in their isotropic melt or solution state. This Perspective discusses fundamental mechanistic principles of this polymerization and bridges with the polymerization of dendronized cyclic iminoethers forming polymers that self‐organize soft Frank–Kasper and quasicrystal periodic and quasiperiodic arrays. These two fields represent frontiers in macromolecular and supramolecular science. A brief discussion of the impact of this polymerization on biomaterials and how it impacted contemporary mechanistic investigations is also made. Expected impacts via future synthetic developments and mechanistic investigations are discussed.
Heat transfer and electromagnetic property investigation on the hot air quartz fiber/PTFE capillary/epoxy resin anti/de‐icing composites
Authors: Chen Long , Zhu Chenyang , Chen Weishi , Liu Zhanqiang , Song Qinghua 
Published: October 2024

AbstractTo achieve the wave‐transparent and anti/de‐icing requirements of electromagnetic functional structural components on the windward surface of the aircraft, the PTFE capillary hot air tubes were pre‐buried inside the quartz fiber cloth and the hot air anti/de‐icing quartz fiber/PTFE capillary/epoxy resin (QF/PTFE/EP) composite components was prepared to that met the wave‐transparent performance. A multi‐field coupled numerical finite element simulation model was established, and the anti/de‐icing performance of the QF/PTFE/EP composite with different built‐in tube diameters were investigated by combining experiments and simulations under different hot air temperatures and pressures. The feasibility of hot air anti/de‐icing was verified through anti/de‐icing experiments and numerical simulation. The electromagnetic transmittance of the prepared hot air anti/de‐icing QF/PTFE/EP composite components was tested to characterize the effect on the stealth performance of the aircraft under the service environment. The experimental results demonstrated that with 5 mm tube pitch and hot air of 60°C ± 1°C, the surface temperature of the component with three tube diameters could reach more than 10°C. Furthermore, the decrease in the transmittance of the hot air anti/de‐icing QF/PTFE/EP composite components caused by different incidence angles and two polarization modes was less than 3%.Highlights
The hot air QF/PTFE/EP anti/de‐icing composite components were fabricated.
The heat transfer, anti/de‐icing, and electromagnetic transmittance performance of the hot air QF/PTFE/EP anti/de‐icing QF/PTFE/EP components were investigated.
The experimental and simulation results verified the hot air anti/de‐icing QF/PTFE/EP components met the requirement of aircraft anti/de‐icing and wave transmission.
Continuous positive airway pressure in delivery room in extremely preterm infants: A single‐center retrospective study in China
Authors: Zhang Xiaoting , Chen Long , Zhong Xiaoyun , Ou Jiangfeng , Shi Yuan 
Published: October 2024

AbstractTo assess the beneficial effects of delivery room continuous positive airway pressure (DRCPAP) in extremely preterm infants, a single‐center retrospective study was performed at the Women and Children's Hospital of Chongqing Medical University in China. Infants born between January 2016 and December 2018 were regarded as the control group, and those born between January 2019 and August 2022 were considered as the observation group (DRCPAP group). The primary outcome was tracheal intubation within 72 h after birth. Six hundred and seven patients were included in the study (control: 232; DRCPAP: 375). Compared with the control group, DRCPAP reduced the intubation rate (56.8% vs. 62.9%, OR 0.57, 95% CI 0.34–0.96, p = 0.035), including <28 weeks gestational age (GA) subgroup (61.5% vs. 84.7%, OR 0.12, 95% CI 0.02–0.78, p = 0.027). One‐to‐one propensity score matching (195:195) was used to match the baseline characteristics of patients in DRCPAP and control group. After matching, no significant differences were observed in intubation rate within 72 h between the two groups (20.5% [40 of 195] vs. 22.1% [43 of 195]; p = 0.711). Whether DRCPAP can reduce intubation rate within 72 h requires further investigation.
Combined analysis of a serum mRNA/miRNA marker signature and CA 19‐9 for timely and accurate diagnosis of recurrence after resection of pancreatic ductal adenocarcinoma: A prospective multicenter cohort study
Authors: Buchholz Malte , Lausser Ludwig , Schenk Miriam , Earl Julie , Lawlor Rita T. , Scarpa Aldo , Sanjuanbenito Alfonso , Carrato Alfredo , Malats Nuria , Tjaden Christine , Giese Nathalia A. , Büchler Markus , Hackert Thilo , Kestler Hans A. , Gress Thomas M. ,   for the BioPaC consortium
Published: October 2024

AbstractBackground and AimsTimely and accurate detection of tumor recurrence in pancreatic ductal adenocarcinoma (PDAC) patients is an urgent and unmet medical need. This study aimed to develop a noninvasive molecular diagnostic procedure for the detection of recurrence after PDAC resection based on quantification of circulating mRNA and miRNA biomarkers in serum samples.MethodsIn a multicentric study, serum samples from a total of 146 patients were prospectively collected after resection. Samples were classified into a “No Evidence of Disease” and a “Recurrence” group based on clinical follow‐up data. A multianalyte biomarker panel was composed of mRNAs and miRNA markers and simultaneously analyzed in serum samples using custom microfluidic qPCR arrays (TaqMan array cards). A diagnostic algorithm was developed combining a 7‐gene marker signature with CA19‐9 data.ResultsThe best‐performing marker combination achieved 90% diagnostic accuracy in predicting the presence of tumor recurrence (98% sensitivity; 84% specificity), clearly outperforming the singular CA 19‐9 analysis. Moreover, time series data obtained by analyzing successively collected samples from 5 patients during extended follow‐up suggested that molecular diagnosis has the potential to detect recurrence earlier than routine clinical procedures.ConclusionsTaqMan array card measurements were found to be biologically valid and technically reproducible. The BioPac multianalyte marker panel is capable of sensitive and accurate detection of recurrence in patients resected for PDAC using a simple blood test. This could allow a closer follow‐up using shorter time intervals than currently used for imaging, thus potentially prompting an earlier work‐up with additional modalities to allow for earlier therapeutic intervention. This study provides a promising approach for improved postoperative monitoring of resected PDAC patients, which is an urgent and unmet clinical need.
Constructing Ecotopian Space as a Protest Against the Urban Worldview in Bibhutibhusan Bandyopadhyay’s Literary Oeuvre
Authors: Mukherjee Indrajit 
Published: October 2024

AbstractErnest Callenbach defined an ecotopian space as an ecologically perfect area or form of imaginary society, a place of refuge from the hustle and bustle of modern metropolitan life. The concept of an ecotopia serves as an appeal to avoid acts of violent aggression that are damaging to the environment and calls for a shift in cultural norms to address the present ecological catastrophe. In Bengali writer Bibhutibhusan Bandyopadhyay’s (1894–1950) literary oeuvre, nature becomes a site of dwelling, a sacred locus bearing witness to the hardships of human existence in the construction of ruthless transformation. This chapter examines the complex relationship between the sacred, natural, and cultural realms in his fiction. This chapter considers how the author employed the natural world as a medium to voice his resistance strategy to the rapid growth of urbanization. This chapter explores how Bandyopadhyay purposefully emphasized the environmental thought to coalesce around the importance of conserving forests, wildlife, and flora in an era, particularly when globalization has “given rise to the threat of global warming and mass extinction” (Chakrabarty, 2021, p. 7). Works to be considered include some of Bandyopadhyay’s most prominent nature narratives, such as Pather Panchali (1929), Aparajito (1932), Aranyak (1932), and Ichhamati (1950).
Indigenous Nature Conservation in Meghalaya: Environmental and Religious Dimensions of Tribal Land Ownership Among the Khasi Community
Authors: Bhattacharjee Srijani 
Published: October 2024

AbstractThe paper is an effort to understand the tradition of sacred groves among the Khasi community of Meghalaya and its role in the preservation of nature in the areas inhabited by them. It attempts to historically understand the factors that have contributed to the gradual erosion and destruction of this institution among the Khasi people across years and with changing regimes. The chapter tries to show that apart from factors such as commercial exploitation of forests as usually held responsible for environmental damage, aspects like flaws within the forest administrative structure are also accountable for injuries caused to sacred groves in the Khasi-populated districts of Meghalaya.
Preface
Authors: Huang Minchao , Wu Jianjun , Li Jian , Cheng Yuqiang 
Published: October 2024

AbstractThe continuous development of space exploration technology requires more efficient and economical space transport systems, and there is an urgent need for propulsion systems that are more efficient than chemical propulsion. Solar thermal propulsion (STP) systems have a relatively small size and high specific impulse, thus offering performance advantages in specific space missions. An STP system is generally composed of a concentrator, heat exchanger core, nozzle, and propellant supply system. The concentrator typically uses parabolic mirrors to concentrate sunlight to heat the heat exchanger core at a focal point. The propellant is heated when it flows through the heat exchanger core and is finally expanded and accelerated by a Laval nozzle to generate thrust. In this propulsion mode, the propulsion system can generate a Newton-level thrust by using an expandable whirling-membrane concentrator with an area of approximately 10 m2 to collect solar radiation. Because hydrogen has a small molar mass and can generate a high exhaust velocity, it is an ideal propellant for solar thermal thrusters. The theoretical specific impulse of an STP using hydrogen as a propellant can reach 800 s. However, the low molar mass of hydrogen also reduces the thrust that the engine can provide, limiting the STP system to low-thrust space missions. The main applications of STP systems are orbit transfer and interplanetary exploration, which require a thrust level between 0.1 and 40 N. Figure 1.1 compares the thrust ranges and specific impulse ranges of several common propulsion methods. Chemical propulsion has a large thrust and a low specific impulse, and electric propulsion has a high specific impulse but a very small thrust. Within the size range of currently achievable spacecraft platforms, the specific impulse and thrust characteristics of STP systems are very attractive, and their high specific impulse and moderate thrust fill the gap between chemical and electric propulsion systems; as such, they are expected to be used to increase the payload ratio of orbital transfer vehicles (OTVs) or orbital maneuvering vehicles (OMVs).
Thrust of Solar Thermal Thruster Under Variable Working Conditions
Authors: Huang Minchao , Wu Jianjun , Li Jian , Cheng Yuqiang 
Published: October 2024

AbstractExperiments are conducted on the STP system built in Chap. 9 to test the thrust of the solar thermal thruster under different working conditions. In this chapter, the heating power and propellant flow rate are changed to change the thrust.