bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mentha crispa e fembendazol no tratamento de parasitoses: um estudo clínico
Authors: Carlos Camila Zeferino , Nunes Poliana Ferraz , Silva Tainá da , Silva Angélica do Rocio Carvalho 
Published: May 2017

The gastrointestinal parasites are pathogens found in pets, causing serious disorders. Due to its incidence and resistance to drugs commonly used many plants are being studied so they can be used in the treatment of several diseases, such as Mentha crispa. The purpose of this study was to evaluate the effect of Mentha crispa comparatively with fenbendazole in the treatment of parasitic infections in dogs and cats. We used four dogs and six cats for the treatment with fenbendazole and six dogs and five cats for Mentha crispa. As a result, both the extract of Mentha crispa and fenbendazole were effective after the first administration against the parasitc infections found in the dogs, except for Giardia sp, however, it was effective against this species after the second administration. For cats, both treatments were not effective against protozoan, the only genre of parasite found in these animals.
Experimental measurements about harmonic current mitigation of electric vehicle battery chargers
Authors: L. Sainz  , J. Balcells  
Published: May 2017

The expected high penetration of battery chargersfor electric vehicles (EV) in electric networks is foreseen as apotential problem for power quality. Battery chargers are non-linear devices that inject harmonic currents and pollute networkvoltages. Thus, their harmonic emissions must be analyzed andreduced by harmonic mitigation techniques to avoid futureproblems. This paper analyzes and reports some real casemeasurements of harmonics injected by single- and three-phasebattery chargers and their attenuation using line chokeinductances.
DC/DC converters as linkages between photovoltaic plants and module integrated multilevel-inverters
Authors: G. Mehlmann  , F. Schirmer  , M. Zeuß  , G. Herold  
Published: May 2017

In Europephotovoltaic plants are mainlyworking in parallel mains operation. Until now, the solar plants are usually grid connected via central inverter stations or via string inverters. The logical advancement of the string con-cept is the separate connection of each solar module to the grid. Therefore module integrated inverters or multilevel-inverters can be used. This concept has some advantages, as minimized mismatching losses and minimized DC wiring. But the circuit complexity is of course much higher. In this paper the layout and implementation of DC/DC-converters as linkages between solar modules and multilevel-inverters will be presented.
Aktivitas Antimikroba Ekstrak dan Fraksi Ekstrak Daun Rami (Boehmeria virgata (Forst.) Guill Terhadap Beberapa Mikroba Organisme
Authors: Ibrahim Arsyik 
Published: May 2017

ABSTRACT

This study aims to the antimicrobial activity test of leaf extract of B. virgata, and the Minimum Inhibitory Concentration values determine toâ€‹â€‹ against some microbes with solid dilution method The materials in maceration with methanol were obtained with 500 grams, than partitioned with solid liquid partition method to use n-hexane, methanol-soluble extract obtained by n-hexane and methanol extracts insoluble n-hexane, both extracts was chemical component monitoring with Thin Layer Chromatography (TLC), then tested with solid dilution method its activity. Antimicrobial activity test results from both types of extracts, methanol extract soluble fraction of n-hexane showed better than activity methanol extract of insoluble fraction of n-hexane, because it can inhibit the growth of the bacteria E. coli, V. cholerae and S. thyposa, while the methanol extract of n-hexane insoluble only able to inhibit the bacteria V. cholerae, methanol-soluble extract fraction of n-hexane as the active extracts 1000 ug / ml medium that can kill or inhibit of microbes the growth.

Keywords: Leaf B. virgata, Antimicrobial, Methanol extract soluble and insoluble n-hexane, Solid Dilution

ABSTRAK

Penelitian ini bertujuan untuk menguji aktivitas antimikroba ekstrak daun B. virgata, dan menentukan nilai Kadar Hambat Minimum dengan metode dilusi padat terhadap beberapa mikroba uji. Bahan uji diperoleh dengan maserasi 500 gram daun dengan metanol yang dilanjutkan dipartisi dengan n-heksan dengan metode partisi padat cair, diperoleh ekstrak metanol larut n-heksan dan ekstrak metanol tidak larut n-heksan, kedua ekstrak ini dimonitoring komponen kimianya dengan metode Kromatografi Lapis Tipis (KLT), kemudian diuji aktivitasnya dengan metode dilusi padat. Hasil uji aktivitas antimikroba dari kedua jenis ekstrak yang diuji, fraksi ekstrak metanol larut n-heksan menunjukkan aktivitas yang lebih baik dibandingkan dengan fraksi ekstrak metanol tidak larut n-heksan, karena dapat menghambat pertumbuhan bakteri E. coli, V. cholerae dan S. thyposa, sedangkan ekstrak metanol tidak larut n-heksan hanya mampu menghambat bakteri V. cholerae, Fraksi ekstrak metanol larut n-heksan sebagai ekstrak aktif yang dapat membunuh/menghambat pertumbuhan mikroba 1000 Âµg/mL medium.

Kata Kunci: Daun B. virgata, Antimikroba, Ekstrak metanol larut dan tidak larut n-heksan, Dilusi Padat
Evaluasi Penggunaan Antibiotika Berdasarkan Kontraindikasi, Efek Samping, dan Interaksi Obat pada Pasien Rawat Inap dengan Infeksi Saluran Pernapasan Bawah Di Rumah Sakit Panti Rapih Yogyakarta Periode Januari-Juni 2005
Authors: Prasetya Fajar 
Published: May 2017

ABSTRACT

The non-TBC lower respiratory infection is a kind of infection that can attack bronchus, bronchioles and lung, the clinical manifestation can chronicle and severe. Generally the caused in children is virus and bacteria while in adult is bacteria, which is using antibiotics in medical attention. The purpose of research is to find out the infection pattern and the kind of antibiotics and to evaluate the using antibiotics based on effectivity. The non-experimental research that was form in a retrospective survey was done through medical record of patient with the lower respiratory infection in the time limit of January-June 2005 in Panti Rapih Hospital. The using of antibiotics was surveyed from medical record then analyzed using quantitative descriptive and presented in percentage. The results obtained showed that the contraindications and adverse reactions of drugs are not found, the incidence of drug interactions by 22 (16%) of 137 cases and of 29 types of antibiotics are used there are 7 species (24%) of potential antibiotic drug interactions. Several cases of potential interactions occurs not show clinical manifestations in patients. To avoid unwanted adverse reactions serum creatinine should be monitored especially in the use of aminoglycoside antibiotics group.

Keywords: lower respiratory infection, usage, antibiotics evaluation, contraindications, adverse reactions, interactions

ABSTRAK

Infeksi saluran pernapasan bawah non TBC merupakan suatu golongan infeksi yang dapat menyerang bronkus, bronkiolis, dan paru, manifestasi kliniknya dapat bersifat akut dan kronis. Umumnya pada anak-anak penyebabnya adalah virus dan bakteri serta pada orang dewasa penyebabnya adalah bakteri, yang dalam pengobatannya menggunakan antibiotika. Penelitian ini bertujuan mengevaluasi penggunaan antibiotika berdasarkan kontraindikasi, efek samping, dan interaksi obat. Penelitian non eksperimental yang berbentuk survei retrospektif dilakukan melalui rekam medik pasien dengan infeksi saluran pernapasan bawah yang menjalani rawat inap pada kurun waktu Januari-Juni 2005 di RS Panti Rapih Yogyakarta. Penggunaan antibiotika dikaji dari data rekam medik kemudian dianalisis secara deskriftif kuantitatif yang dinyatakan dengan presentase. Hasil penelitian yang diperoleh menunjukan bahwa kontraindikasi dan efek samping obat tidak ditemukan, kejadian interaksi obat sebesar 22 (16%) dari 137 kasus dan dari 29 jenis antibiotika yang digunakan terdapat 7 jenis (24%) antibiotika yang potensial terjadi interaksi obat. Beberapa kasus interaksi yang potensial terjadi tidak menunjukan manifestasi klinik pada pasien. Untuk menghindari efek samping yang tidak dikehendaki perlu dilakukan monitoring serum kreatinin terutama pada penggunaan antibiotika golongan aminoglikosida.

Kata Kunci: infeksi saluran pernapasan bawah, penggunaan, evaluasi antibiotika, kontraindikasi, efek samping, interaksi
Efek Pemberian ?-Mangostin dari Garcinia tetranda Pierre Terhadap Morfologi P.falciparum
Authors: Kuncoro Hadi 
Published: May 2017

ABSTRACT

Morphological changes assay to P. falciparum from the effects of Î±-mangostin from G. tetranda using TEM methods has been done. This test aims to determine the effect of mangostin on P. falciparum by observing morphological ultrastructure of P. falciparum using transmission electron microscope (TEM). Î±-Mangostin known to cause morphological changes in ultrastructure of P.falciparum after contact with Î±- mangostin on the 12 and 24 hour.

Key words: Î±- Mangostin, G. tetranda, P. falciparum, Transmission Electron microscope (TEM)

ABSTRAK

Telah dilakukan pengujian terhadap perubahan morfologi P. falciparum akibat efek pemberian Î±-mangostin dari G. tetranda menggunakan metode TEM. Pengujian ini bertujuan untuk mengetahui efek pemberian mangostin kepada P. falciparum dengan melakukan pengamatan ultrastruktur dari morfologi P. falciparum menggunakan Mikroskop Elektron transmisi (TEM). Diketahui Î±-Mangostin menyebabkan perubahan morfologi pada ultrastruktur dari P.falciparum setelah pemberian Î±-mangostin pada jam ke 12 dan 24.

Kata Kunci: Î±-Mangostin, G. tetranda, P. falciparum, Mikroskop Elektron Transmisi.
Salt Stress induced changes in growth, pigments and protein contents in two horse gram [Macrotyloma uniflorum (Lam.) Verdc] varieties
Authors: C. Sathish G. Kanagaraj* and 
Published: May 2017

Growth parameters and photosynthetic pigments changes in horse gram were investigated under salinity of different concentrations (0, 40, 80. 120mM). The two horse gram varieties Paiyur-2 and CO-1 were sampling was done in young and fully matured leaves were taken from control and salinity treated plants on 15th Days After Treatment (DAT) and 30th DAT. Treatments were planted in pots. Growth parameters such as plant height, lea area, fresh and dry weight of the whole plants decreased in both varieties under salinity stressed condition. Photosynthetic pigments such as total chlorophyll, chlorophyll ‘a’ chlorophyll ‘b’ were significantly reduced in the salinity stressed leaves. Quantitative differences with response to salinity. Were also noticed in the content of soluble protein in two horse gram varieties. Our data revealed that Paiyur-2 maintained lower reduction of growth and higher contents of photosynthetic pigments as well as soluble protein content when compared to variety CO-1 during the adverse effect of salinity stress.
De la pertinence historiographique d'une trajectoire individuelle : Lionel Groulx, la Confédération et le Canada français
Authors: Bock Michel 
Published: May 2017

À partir de la double perspective du genre biographique et de l'histoire intellectuelle, cet article a pour objectif de montrer la pertinence de l'étude du parcours de Lionel Groulx, l'un des principaux penseurs du nationalisme canadien-français des années 1910 à la Révolution tranquille des années 1960, au regard de son rapport à la Confédération canadienne. Avec Groulx, il est possible, en effet, de pénétrer le champ intellectuel canadien-français afin d'en comprendre la configuration et de mettre en perspective les facteurs qui en ont façonné l'évolution au XXe siècle. Une approche consistant à historiciser sa pensée, à la situer dans son contexte intellectuel, politique et religieux, permet aussi de comprendre les tensions internes qu'elle recèle en fonction de ses « constantes » et, surtout, des relations qu'il entretenait avec les autres acteurs du champ intellectuel et au contact desquels ses idées se sont en partie construites. En étudiant Groulx à la fois comme le produit et un critique d'un « système normatif » particulier (Giovanni Levi), l'historien évite d'essentialiser le groulxisme et de le réduire, de manière anhistorique, à une simple juxtaposition de contradictions irréductibles.
Predictors of extended length of stay, discharge to inpatient rehab, and hospital readmission following elective lumbar spine surgery: introduction of the Carolina-Semmes Grading Scale
Authors: McGirt Matthew J. , Parker Scott L. , Chotai Silky , Pfortmiller Deborah , Sorenson Jeffrey M. , Foley Kevin , Asher Anthony L. 
Published: May 2017

OBJECTIVEExtended hospital length of stay (LOS), unplanned hospital readmission, and need for inpatient rehabilitation after elective spine surgery contribute significantly to the variation in surgical health care costs. As novel payment models shift the risk of cost overruns from payers to providers, understanding patient-level risk of LOS, readmission, and inpatient rehabilitation is critical. The authors set out to develop a grading scale that effectively stratifies risk of these costly events after elective surgery for degenerative lumbar pathologies.METHODSThe Quality and Outcomes Database (QOD) registry prospectively enrolls patients undergoing surgery for degenerative lumbar spine disease. This registry was queried for patients who had undergone elective 1- to 3-level lumbar surgery for degenerative spine pathology. The association between preoperative patient variables and extended postoperative hospital LOS (LOS ≥ 7 days), discharge status (inpatient facility vs home), and 90-day hospital readmission was assessed using stepwise multivariate logistic regression. The Carolina-Semmes grading scale was constructed using the independent predictors for LOS (0–12 points), discharge to inpatient facility (0–18 points), and 90-day readmission (0–6 points), and its performance was assessed using the QOD data set. The performance of the grading scale was then confirmed separately after using it in 2 separate neurosurgery practice sites (Carolina Neurosurgery & Spine Associates [CNSA] and Semmes Murphey Clinic).RESULTSA total of 6921 patients were analyzed. Overall, 290 (4.2%) patients required extended LOS, 654 (9.4%) required inpatient facility care/rehabilitation on hospital discharge, and 474 (6.8%) were readmitted to the hospital within 90 days postdischarge. Variables that remained as independently associated with these unplanned events in multivariate analysis included age ≥ 70 years, American Society of Anesthesiologists Physical Classification System class > III, Oswestry Disability Index score ≥ 70, diabetes, Medicare/Medicaid, nonindependent ambulation, and fusion. Increasing point totals in the Carolina-Semmes scale effectively stratified the incidence of extended LOS, discharge to facility, and readmission in a stepwise fashion in both the aggregate QOD data set and when subsequently applied to the CNSA/Semmes Murphey practice groups.CONCLUSIONSThe authors introduce the Carolina-Semmes grading scale that effectively stratifies the risk of prolonged hospital stay, need for postdischarge inpatient facility care, and 90-day hospital readmission for patients undergoing first-time elective 1- to 3-level degenerative lumbar spine surgery. This grading scale may be helpful in identifying patients who may require additional resource utilization within a global period after surgery.
Fifteen microsatellite markers for Herbertia zebrina (Iridaceae): An endangered species from South American grasslands
Authors: Forgiarini Cristiane , Curto Manuel , Stiehl‐Alves Eudes Maria , Bräuchler Christian , Kollmann Johannes , Meimberg Harald , Teixeira de Souza‐Chies Tatiana 
Published: May 2017

Premise of the study:Polymorphic microsatellite loci were developed and used to genotype individuals of Herbertia zebrina (Iridaceae) as a first step for assessment of intraspecific genetic diversity.Methods and Results:Primer pairs for 47 markers were developed: 20 from a microsatellite‐enriched library and 27 from a next‐generation sequencing run using the Illumina MiSeq platform. Of those, 15 loci were considered successful, of which 12 were polymorphic and three were monomorphic. The primers were tested in 50 individuals from three populations of H. zebrina. Two to 14 alleles per locus were identified, and observed and expected heterozygosity were 0.00–0.95 and 0.18–0.89, respectively. Tests of cross‐amplification to evaluate the applicability of these markers showed positive results in one congeneric species, H. darwinii, and in a phylogenetically closely related species, Calydorea crocoides.Conclusions:These microsatellite markers can be used for studies of genetic variation and genetic population structure, as well as to support conservation efforts.
Steep Decay Phase Shaped by the Curvature Effect. I. Flux Evolution
Authors: Lin Da-Bin , Mu Hui-Jun , Lu Rui-Jing , Liu Tong , Gu Wei-Min , Liang Yun-Feng , Wang Xiang-Gao , Liang En-Wei 
Published: May 2017

Abstract
The curvature effect may be responsible for the steep decay phase observed in gamma-ray bursts. To test the curvature effect with observations, the zero time point t
0 adopted to plot the observer time and flux on a logarithmic scale should be appropriately selected. In practice, however, the true t
0 cannot be directly constrained from the data. Thus, we move t
0 to a certain time in the steep decay phase, which can be easily identified. In this situation, we derive an analytical formula to describe the flux evolution of the steep decay phase. The analytical formula reads as

with

, where F

ν
is the flux observed at frequency ν,

is the observer time by setting t
0 at a certain time in the steep decay phase, β is the spectral index estimated around ν, and

is the decay timescale of the phase with

. We test the analytical formula with the data from numerical calculations. It is found that the analytical formula presents a good estimate of the evolution of the flux shaped by the curvature effect. Our analytical formula can be used to confront the curvature effect with observations and estimate the decay timescale of the steep decay phase.
Using Ice and Dust Lines to Constrain the Surface Densities of Protoplanetary Disks
Authors: Powell Diana , Murray-Clay Ruth , Schlichting Hilke E. 
Published: May 2017

Abstract
We present a novel method for determining the surface density of protoplanetary disks through consideration of disk “dust lines,” which indicate the observed disk radial scale at different observational wavelengths. This method relies on the assumption that the processes of particle growth and drift control the radial scale of the disk at late stages of disk evolution such that the lifetime of the disk is equal to both the drift timescale and growth timescale of the maximum particle size at a given dust line. We provide an initial proof of concept of our model through an application to the disk TW Hya and are able to estimate the disk dust-to-gas ratio, CO abundance, and accretion rate in addition to the total disk surface density. We find that our derived surface density profile and dust-to-gas ratio are consistent with the lower limits found through measurements of HD gas. The CO ice line also depends on surface density through grain adsorption rates and drift and we find that our theoretical CO ice line estimates have clear observational analogues. We further apply our model to a large parameter space of theoretical disks and find three observational diagnostics that may be used to test its validity. First, we predict that the dust lines of disks other than TW Hya will be consistent with the normalized CO surface density profile shape for those disks. Second, surface density profiles that we derive from disk ice lines should match those derived from disk dust lines. Finally, we predict that disk dust and ice lines will scale oppositely, as a function of surface density, across a large sample of disks.
Antibacterial Effects of Antiretrovirals, Potential Implications for Microbiome Studies in HIV
Authors: Shilaih Mohaned , Angst Daniel C , Marzel Alex , Bonhoeffer Sebastian , Günthard Huldrych F , Kouyos Roger D 
Published: May 2017

Background Despite being used by more than 18 million people our understanding of the extent of the effects of antiretrovirals on the human body and other organisms remains incomplete. In addition, the direct effect of antiretrovirals on the gut microbiota of HIV-infected individuals has been largely overlooked in microbiome studies concerned with HIV-infected individuals. Methods Here we tested 25 antiretrovirals on Bacillus subtilis and Escherichia coli using a broth microdilution assay to assess whether these drugs have an antibacterial effect. Results We found that several widely used antiretroviral drugs have in vitro antibacterial activity against both gram-positive and gram-negative commensal bacteria. Efavirenz inhibited the growth of B. subtilis with a minimum inhibitory concentration (MIC) of 16 μg/ml (in all three replicates), while 2‘,3‘-dideoxyinosine and zidovudine inhibited the growth of E. coli with an MIC of 16–32 μg/ml and 0.016–0.125 μg/ml (respectively). Conclusions Given the large and increasing number of individuals on antiretrovirals, and the lifelong nature of HIV treatment, this proof-of-concept report could have several potential implications, including an impact of antiretrovirals on bacterial coinfections, as well as potentials for drug discovery and repositioning.