bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative analysis and optimal allocation of virtual inertia from grid‐forming and grid‐following controlled ESSs
Authors: Zhu Naixuan , Hu Pengfei , Jiang Chongxi , Yu Yanxue , Jiang Daozhuo 
Published: September 2024

AbstractA broad consensus of neutralizing the carbon dioxide emissions facilitates the transition to the renewable energy power system. Meanwhile, the concerns about the volatility of renewable energies are growing as the rotational inertia of power system becomes inadequate. To maintain the frequency stability of power system, some studies for configuring inertia energy storage systems (ESSs) are carried out, mainly focusing on the allocation of virtual inertia from grid‐forming ESS. In contrast, the allocation of virtual inertia from grid‐following ESS has not been well elaborated and the differences in virtual inertia provided by these two modes are yet to be revealed. Based on ‐norm and Kron reduction, firstly, the state‐space model of post‐disturbance system is established, together with the transient performance evaluation. Then the inertia characteristics of both grid‐forming and grid‐following devices are formulated, followed by the unified gradient descent optimization method for allocating virtual inertia. A modified IEEE 39‐bus system and its time‐domain simulations help in the verification of the contribution of this paper. Through the comparative analysis of corresponding optimal results, the conclusions from two aspects are drawn: in terms of transient frequency support, the grid‐forming devices can provide no less than better inertia support; with the higher power capacity and similar energy capacity, the grid‐forming devices can relieve the response pressure of other generators by approximately .
En quête de métaphores, une proposition méthodologique. Le cas des sols agricoles
Authors: Taddei Antonia , Fallot Abigaïl , Perié Leïla 
Published: September 2024

Nous présentons une méthode pour relever les différentes métaphores utilisées dans un domaine scientifique, et voir comment elles peuvent servir au mieux la recherche et ses applications. Prenant comme point de départ les métaphores utilisées pour parler des sols agricoles, nous avons élaboré cette méthode d’enquête métaphorique pour accompagner la compréhension et la formulation de réponses à la hauteur des enjeux sociaux et écologiques autour des sols agricoles. Comme chaque métaphore apporte un éclairage singulier sur la question étudiée, mais laisse d’autres aspects « dans l’ombre », il apparaît essentiel d’étudier et d’utiliser les métaphores dans leur pluralité. La méthode consiste : à révéler une diversité de métaphores ; à les organiser par ensembles ; à préciser et questionner les éléments de compréhension apportés par chaque ensemble, mais également ses limites ; à compléter ces éclairages en interrogeant les spécialistes du sujet. Il en résulte un partage vivant des connaissances et des représentations, ouvert au dialogue entre sciences et société, qui dans le cas des sols offre de nouvelles façons de les considérer et les étudier afin de mieux contrer leur dégradation.
PlantCoopLab, coopérer avec les plantes pour une alimentation durable
Authors: Pouteau Sylvie , Javelle Aurélie , Mouret Sébastien , Pignier Nicole , Pinton Florence , Porcher Jocelyne 
Published: September 2024

Autant le statut des animaux dans les systèmes productifs fait l’objet de débats, autant la définition de la durabilité alimentaire n’implique aucun égard particulier pour les plantes. Le projet PlantCoopLab trouve son inspiration dans ce constat et dans le « tournant végétal » qui appelle à revisiter le statut des plantes. Dans une logique de production économique, faire signifie en général produire des biens ou des services par le travail. Dans le cas des plantes, le « faire » est-il aussi un travail ? Sans pour autant impliquer une personnification, cette question permet de repenser les activités végétales au-delà d’une lecture seulement techniciste, ce qui conduit aussi à reconsidérer le travail effectué avec les plantes. Le projet analyse plus largement la reconnaissance de ce travail comme moyen d’infléchir les pratiques nécessaires à la fourniture de nourritures durables.
Validation de la version francophone de l’Échelle d’Effort Physique
Authors: St-Denis Bianca , Beaudry Simon , Boisgontier Matthieu P. , Cheval Boris , Maltagliati Silvio 
Published: September 2024

Objectif : Pour mieux expliquer l’engagement dans l’activité physique, la Physical Effort Scale (PES) a récemment été développée. L’objectif de la présente étude était de valider la version francophone de cette échelle (PES-FR). Méthodologie : Après traduction de l’échelle originale, la validité structurelle et de construit de la PES-FR a été examinée dans un échantillon de 362 étudiants canadiens francophones (62 % de femmes, Mâge = 20 ans). La stabilité temporelle de l’échelle a été testée dans un second échantillon (n = 101, 79 % de femmes, Mâge = 21 ans) ayant complété deux fois le questionnaire avec sept jours d’écart. Résultats : La structure en deux facteurs de la PES-FR a été soutenue, avec une dimension d’approche et une dimension d’évitement. Les deux sous-échelles présentent une cohérence interne élevée (α = 0,86 pour l’approche et α = 0,89 pour l’évitement). La validité convergente et la validité discriminante ont été confirmées par des corrélations entre l’approche et l’évitement avec plusieurs variables motivationnelles. La validité concurrente de l’échelle a été soutenue par des associations entre le niveau habituel d’activité physique et les tendances d’approche (r = 0,35) et d’évitement (r = −0,21). La stabilité temporelle a aussi été confirmée dans le second échantillon. Conclusions : La PES-FR est un outil fiable et valide pour mesurer les différences individuelles dans l’évaluation de l’effort physique. Les implications pratiques sont discutées au regard des enjeux de promotion de l’activité physique.
NT-pro-BNP Level is Related to Left Ventricular Remodeling in
Patients With Primary Aldosteronism
Authors: Wu Tao , Xu Chenxiao , Tang Lu , Wu Xi , Peng Pengfei , Yue Xun , Cheng Wei , He Shuai , Li Lei , Chen Yucheng , Ren Yan , Sun Jiayu 
Published: September 2024

Abstract
Aims To assess the relationship between the left ventricular remodeling
parameters of cardiac magnetic resonance and NT-pro-BNP in patients with primary
aldosteronism (PA).
Methods Seventy-four PA and 39 essential hypertension patients were
prospectively recruited and underwent cardiac magnetic resonance. Plasma
NT-pro-BNP was measured before patients underwent cardiac magnetic resonance.
Left ventricular remodeling parameters were defined as left ventricular function
parameters, T1 mapping parameters, and strain parameters. Differences in
continuous variables between two groups were analyzed using Student’s t-test or
Mann–Whitney U test. Differences in categorical variables between two groups
were analyzed by chi-squared test. Spearman’s correlation and linear regression
were used to analyze the relationships between left ventricular remodeling
parameters and plasma NT-Pro-BNP level. P<0.05 was considered as
statistically significant.
Results Patients with PA demonstrated higher NT-pro-BNP [86.0 (49.5,
145.5) vs. 45.0 (28.5, 73.5) pg/mL, P=0.001] and Native T1 (1227±41 vs. 1206±43
ms, P=0.015) level than essential hypertension patients. Compared to patients
with normal NT-pro-BNP levels, those with abnormal levels demonstrated different
left ventricular remodeling parameters. NT-pro-BNP level was independently
related to native T1 (β=0.316, P=0.006), extracellular volume (β=0.419,
P<0.001), short-axis global circumferential strain (β=0.429, P<0.001),
four-chamber global longitudinal strain (β=0.332, P=0.002), and four-chamber
global radial strain (β=-0.334, P=0.004) in patients after adjusting for
baseline characteristics.
Conclusions NT-pro-BNP level was related to left ventricular remodeling
parameters derived from cardiac magnetic resonance in patients with PA. This
result implies that clinicians should pay attention to NT-pro-BNP assessment in
patients with PA in routine clinical assessment.
Comparison of Patient-Reported Quality of Life Following Direct-to-Implant Prepectoral and Subpectoral Breast Reconstruction Using BREAST-Q: A Randomized Controlled Trial
Authors: Dyrberg Diana L , Dalaei Farima , Sollie Martin , Bille Camilla , Koudahl Vibeke , Sørensen Jens A , Thomsen Jørn B 
Published: September 2024

Abstract
Background Direct-to-implant breast reconstruction (DIR) is becoming more and more accepted. There is a lack of high-quality studies assessing differences in patient-reported quality of life (QoL) between different implant placement methods. The aim of this randomized controlled (clinical) trial was to compare QoL between women reconstructed by sub- or prepectoral implant placement.
Methods We included women over 18 years eligible for DIR. Patients were randomly assigned to reconstruction by subpectoral or prepectoral implant placement. Assessment of QoL and patient satisfaction was made using the BREAST-Q questionnaire for postmastectomy breast reconstruction and compared between the sub- and prepectoral reconstructed groups preoperatively and after 3 and 12 months of follow-up.
Results A total of 42 women were allocated to sub- or prepectoral reconstruction with 21 patients in each group. There were no differences in patient characteristics between groups. Regarding all the selected BREAST-Q scales: (1) satisfaction with the reconstructed breast, (2) satisfaction with the breast implant, (3) satisfaction with the overall outcome, (4) psychosocial well-being, (5) sexual well-being, and (6) physical well-being—we found no significant differences between the two groups. Assessing each group independently we found, that in both groups sexual well-being improved after surgery postoperatively compared to the preoperative scores.
Conclusion We found high satisfaction and QoL following both sub- and prepectoral breast reconstruction. We found no significant differences between groups suggesting both methods for DIR can be used. Despite our high-quality data, a larger sample size and longer postoperative follow-up are needed to further investigate the differences in QoL between sub- and prepectoral breast reconstruction.
Synthesis of 5-(4-Formylphenyl)barbituric Acid to Access Enolizable Chromophoric Barbituric Acids
Authors: Schade Alexander 
Published: September 2024

AbstractBarbituric acids mono-substituted at the 5-position show keto–enol tautomerism. In the keto form, conjugation to an aryl substituent is interrupted due to the sp³-hybridized carbon atom at the 5-position of barbituric acid. The enol form generates a conjugated π-system to the aryl substituent and acts as an electron-donating group. If the aryl substituent is electron-deficient, a push-pull system is generated that shows typical UV/Vis absorption. These types of compounds are difficult to access synthetically due to their intrinsic convertibility. The synthesis of barbituric acids with a 4-formylphenyl functionality at the 5-position is reported. This compound, 5-(4-formylphenyl)barbituric acid, could be used to introduce extended π-systems with electron-withdrawing groups in great variety by simple condensation reactions. We demonstrate this by a Horner–Wadsworth–Emmons reaction that forms the enolizable dye (E)-5-(4-(4-nitrostyryl)phenyl)barbituric acid.
Structure-Based Virtual Screening and Protein–Protein Docking Analysis of ERBB2 and Associated Proteins for Pediatric Cancer Therapeutic Approaches
Authors: Almazroea Abdulhadi 
Published: September 2024

Abstract
Introduction The Erythroblastosis Oncogene B homolog 2 (ERBB2) protein, also known as human epidermal growth factor receptor 2 (HER2), is a key player in cancer growth, especially in neuroblastoma and gastric cancers. Targeting ERBB2 has led to successful therapies, making it an important focus in cancer research with the potential to improve treatment for HER2-positive cancers.
Objective The primary goal of this research is to employ a multifaceted computational approach to identify potential drug candidates targeting ERBB2. We aim to combine virtual screening, protein–protein docking, and functional partner prediction to provide insights into the molecular interactions and potential efficacy of the identified compounds. Additionally, we intend to assess the safety profiles of these compounds using advanced toxicity prediction tools.
Materials and Methods Relevant protein sequence and structural data for ERBB2 and epidermal growth factor receptor (EGFR) were sourced from publicly available databases. Potential inhibitors from the Enamine and LifeChemicals databases were identified through virtual screening using AutoDock Vina. Functional partners of ERBB2 were explored using STRING, KEGG, and REACTOME servers. The identified compounds were subjected to toxicity prediction using the ProTox-II server.
Results Virtual screening led to the selection of 10 compounds with favorable binding energies (–8.346 to –6.296 kcal/mol) and specific amino acid interactions (Thr5, Arg412, Leu414, and Ser441) with the receptor. On the other hand, EGFR was identified as the best functional partner for ERBB2. The EGFR residues Gln408, Lys463, Phe412, and Asp436 found key residues for the complex formation. The toxicity prediction analysis revealed that the majority of compounds exhibited acceptable safety profiles, although a subset of compounds showed lower prediction scores, suggesting the need for further consideration.
Conclusion This comprehensive computational approach, integrating virtual screening, protein–protein docking, functional partner identification, and toxicity prediction, offers a systematic framework for efficient drug discovery. The identification of potential lead compounds targeting ERBB2, with emphasis on both binding affinity and safety, underscores the significance of such an approach in streamlining the drug development process. By prioritizing compounds with promising efficacy, functional relevance, and acceptable toxicity profiles, this study advances our understanding of potential therapeutic agents, enhancing the likelihood of successful translation from computational predictions to real-world drug candidates.
Coexistence of 21 Hydroxylase Deficiency and Autoimmune Adrenalitis: A Case Report
Authors: Trimeche Oumeyma , Minf Fatma , Salah Dhoha Ben , Frikha Hamdi , Elleuch Mouna , Kacem Faten Hadj , Charfi Nadia , Boujelbene Khouloud , Mnif Mouna , Rekik Nabila , Abid Mohamed 
Published: September 2024

Abstract21-Hydroxylase deficiency (21 OHD) is the most common cause of congenital adrenal hyperplasia (CAH). Despite its relative frequency, many aspects of this disease are understudied. The aim of our case report was to highlight the association between nonclassic CAH (NCCAH) and autoimmunity, and to encourage future research to explore the possible cause-and-effect relationship between CAH and tumorigenesis. Here, we report the case of a 41-year-old woman with a history of nonclassic 21 OHD, who demonstrated typical signs of acute adrenal insufficiency. As it is well known, this is an unusual presentation of NCCAH and therefore a panel of laboratory and radiological exams were conducted in order to determine the associated etiology of the adrenal insufficiency, which revealed to be autoimmune adrenalitis. Another striking particularity of our case is the coexistence of NCCAH and cutaneous T lymphoma in our patient, which to our knowledge has never been reported in literature. This case illustrates the need to scrutiny for the etiology of adrenocortical crisis in the setting of NCCAH. It also emphasizes the possible associations between NCCAH and autoimmunity in one hand and neoplasms on the other hand.
Challenges in Targeting the “Crosstalks” in Cancer Cachexia
Authors: Vallathol Dilip Harindran , Warrier Arun R. 
Published: September 2024

AbstractCancer cachexia syndrome is characterized by involuntary weight loss which usually occurs in advanced malignancies. The pathogenicity of this syndrome is multifactorial, due to a complex interaction of tumor and host factors. The syndrome is closely related to the prognostication of malignancies. Several research works are in progress to target the major effectors of cancer cachexia syndrome. This letter is a nutshell on the current status of the cancer cachexia syndrome—the crosstalks and potential therapeutic targets.
Understanding Cancer Epidemiology in Himachal Pradesh, India
Authors: Ranta Randhir Singh , Sharma Sakshi , Chauhan Manoj 
Published: September 2024

Objective This study investigated the distribution of cancer cases across different age groups, sexes, and regions in Himachal Pradesh, India, with the aim of informing targeted public health strategies.
Materials and Methods Cancer incidence data were collected from various age groups, sexes, and blocks.
Statistical Analysis Chi-square tests were used to assess the significance of differences in cancer patient distribution according to age, sex, and region.
Results Cancer incidence increased with age, peaking in the 58 to 67 years age group. The highest number of patient was reported, particularly among individuals aged 38 years and above. Minimal cases were observed in the youngest age groups (< 17 and 18–27 years), while a significant increase was noted in the middle age groups (28–57 years). Cancer cases were nearly equally distributed between males (50.1%) and females (49.9%). A chi-square value of 180.18 indicated a statistically significant difference in cancer incidence according to age and sex. Gender-specific trends revealed higher cancer incidences in females during middle age (28–57 years) and in males during older age (58 years and above). The highest number of cases was 18.1%, followed by 14.7 and 14.6%, while the lowest incidence was 1.5%.
Conclusion The present study underscores the need for comprehensive and targeted public health strategies to manage cancer burdens effectively. Focusing on high-incidence regions and ensuring equitable health care access for all genders can improve cancer outcomes and reduce mortality rates associated with the disease.
Splenic and Liver Elastography in Prediction of Esophageal Varices and Variceal Severity in Patients with Chronic Liver Disease: A Diagnostic Validation Study
Authors: Panthee Trilochan , Nandolia Khanak K. , Sharma Pankaj , Patnaik Itish , Chauhan Udit 
Published: September 2024

Abstract
Objective The aim of this study was to assess the value of shear wave elastography (SWE) to predict the presence of esophageal varices (EVs) and to predict high-grade EV in patients with chronic liver disease (CLD).
Methods A cross-sectional observational study was conducted. One hundred twenty-one CLD patients were recruited. Liver stiffness (LS) and splenic stiffness (SS) were measured using SWE.
Results Evaluation of LS is superior to SS in predicting the presence of EV. Evaluation of SS is more valuable than LS in grading EV.
Conclusion LS and SS have good diagnostic performance in predicting and grading varices. SWE is simple to incorporate into standard ultrasonography assessments in patients with CLD. SWE can be used as an adjunct to upper gastrointestinal endoscopy to screen and monitor CLD patient.
‘A Reputation to Protect’: Sport-Team Reputation as a Strategic Source of Brand Equity
Authors: Mishra Abhishek , Yousaf Anish , Gannon Martin 
Published: September 2024

AbstractThis study investigates how sports team reputation shapes brand equity through consumers’ relationship satisfaction, life satisfaction, and commitment. Data were collected from India in two stages, with 523 responses used to test relationships among constructs via structural equation modelling. Barring the effects of social responsibility and financial soundness on relationship satisfaction and the effect of life satisfaction on team brand equity, all hypothesised relationships were significant. Self-congruity also positively moderated relationship satisfaction outcomes, including sport-team heritage, spectator orientation, and management style dimensions. The study’s findings provide important insights for managers, highlighting the crucial role of a strong reputation in building consumer-team loyalty. Our research suggests that marketing strategies should focus on enhancing consumer self-identification by involving fans in on-field and off-field successes to foster meaningful connections.
Accreditation as a lever for change in the development of the collaborative practitioner in the Australian health system
Authors: Kent Fiona , Cardiff Lynda , Clark Bronwyn , Gustavs Julie , Jolly Brian , Maundu Josephine , Wilkinson Glenys , Meiklejohn Sarah 
Published: September 2024

Objective Patient expectations in the Australian healthcare system are for coordinated, collaborative practice. There is a need for education institutions, health services, accreditation authorities, and consumers to work together to achieve this goal. As part of a larger body of work, we sought to understand how these stakeholders contribute to the development of collaborative healthcare practice. Method Nineteen focus groups were conducted in 2022 with 84 participants consisting of education providers (n = 62), consumers (n = 10), representatives from the Health Profession’s Education Standing Group (n = 8), and health service practitioners (n = 4). Framework analysis was initially undertaken to understand facilitators of, and barriers to, collaborative practice and learning. In a secondary analysis, the themes were re-organised according to the Bolman and Deal domains of organisational practice, to make explicit the structural, human resource, political, and symbolic factors deemed useful for re-imaging a process for learning about and incentivising collaborative practice. Results There are multiple factors across healthcare settings that both facilitate and challenge the development of collaborative practice. Co-location of professions and participation in formal interprofessional processes such as team meetings and handovers facilitated learning collaborative practice, although traditional cultures which perpetuate siloed models of healthcare, power differentials between the professions, funding structures, and information sharing limited opportunities. The ‘value’ of collaborative practice was facilitated through both consistent curriculum messages throughout health professional courses and positive role modelling. Conclusions Education institutions, health service practitioners, accreditation authorities, and consumers can work together to facilitate the development of collaborative practice through attention to policy and processes, curriculum activities, student participation, health service activities and practice, and resource allocation.