bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacto psicosocial de las secuelas post covid-19 en comunidades vulnerables: Revisión sistemática
Authors: Ponce Pincay Roberto , Navia Pinargote Brenda Nayeli , Delgado Chávez Yandry Howard , Guamán Ávila Jeison Alexander 
Published: September 2024

Introducción: El impacto del COVID-19 en la salud de las personas post infectadas del virus causo problemas psicológicos y emocionales, alterando el comportamiento, y salud mental de la población; la vulnerabilidad en distintos grupos causa más secuelas en niños, geriátricos, embarazadas, adultos jóvenes, personal de salud, personas con comorbilidades, personas de bajos recursos. Objetivo: Determinar el impacto psicosocial de las secuelas del post COVID-19 en comunidades vulnerables Metodología: Se realizo un estudio de revisión sistemática, utilizando varias bases de datos de revistas científicas publicadas durante 2019-2024, en idioma inglés y español. Resultados: La prevalencia de duración de post secuelas del virus varía dependiendo de la vulnerabilidad de cada persona, ya sea de la tercera edad, niños o pacientes oncológicos, con síntomas duraderos que van de los tres a seis meses. Las post secuelas producen efectos psicológicos mentales negativos. Discusión: Se informa sobre la prevalencia de las secuelas post COVID-19 en la población vulnerable. Se analizaron los efectos físicos y emocionales, así como los efectos psicosociales comunes en estos grupos. Es crucial entender el comportamiento humano durante y después de la pandemia debido a las vulnerabilidades que pueden surgir tras la hospitalización o la enfermedad. Conclusión: El COVID-19 ha impactado gravemente a grupos vulnerables, especialmente a personas mayores y niños (81%), causando secuelas físicas, emocionales y psicológicas, teniendo un impacto en la capacidad muscular, orgánica y física de las actividades que se realizaban a diario, repercutiendo en la ansiedad, depresión y estrés postraumático.
Enfermedad Renal en pacientes con diabetes mellitus, factores de riesgo y manifestaciones clínicas
Authors: Fuentes Parrales Jocelyne Elizabeth , Macías Macías Cristhian Gabriel , Villamar Martínez Stefany Johanna , Zambrano Pico Kelly Sabrina 
Published: September 2024

La Enfermedad Renal Diabética es una complicación microvascular que afecta tanto en la diabetes tipo 1 como al tipo 2, incrementando la morbimortalidad en comparación con aquellos que no la padecen. La enfermedad renal crónica es una condición no transmisible que se ha convertido en un importante problema de salud pública a nivel global. Actualmente, aproximadamente 850 millones de personas en el mundo están diagnosticadas con ERC, y se estima que para el año 2030 esta cifra alcanzará los 14,5 millones. Por otro lado, la Nefropatía Diabética se manifiesta en aproximadamente en el 30% de los pacientes con diabetes mellitus tipo 1 (DM1) y en el 40% de aquellos con diabetes mellitus tipo 2 (DM2). Se tuvo como objetivo, analizar la enfermedad renal en pacientes con diabetes mellitus, factores de riesgo y manifestaciones clínicas, se basó en una revisión narrativa de tipo descriptivo, teniendo como resultado que la hipertensión y la obesidad son los factores de riesgo más prevalentes y que entre las manifestaciones clínicas la presión arterial elevada es la más frecuente, seguida de la anemia y la retinopatía diabética, concluyendo que, la integración de estos factores revela la compleja interacción entre la diabetes la hipertensión y la salud renal, haciendo énfasis de la necesidad de un manejo integral que aborde estos aspectos para prevenir y disminuir las complicaciones de la enfermedad renal. El articulo permitirá la aplicación de conocimientos en asignaturas como salud pública y bioquímica y al proyecto de investigación titulado “Utilidad de Cistatina C en la disfunción renal e identificación de factores de riesgo: un camino hacia la medicina preventiva en habitantes de la ciudad de Jipijapa”, conjunto con el proyecto de vinculación denominado "Influencia del laboratorio clínico en la prevención y diagnóstico de la enfermedad renal en pacientes con diabetes mellitus e hipertensión arterial del sur de Manabí. Fase I.".
Prevención y control de la hipertensión y la diabetes: clave para llevar una vida saludable
Authors: Fuentes Parrales Jocelyne Elizabeth , Macías Velastegui Carlos Alejandro , Marcillo Baque Nayeli Beatriz , Salas Salas Josue Magdiel 
Published: September 2024

El artículo aborda la importancia de las enfermedades crónicas no transmisibles (ECNT), como la hipertensión arterial (HTA) y la diabetes tipo 2 (DM2), consideradas una pandemia por la OMS desde principios del siglo XXI. En el presente artículo se tiene como objetivo realizar una revisión sistemática de como la prevención y control de la hipertensión y la diabetes son clave para llevar una vida saludable La metodología se basó en una revisión sistemática utilizando el diagrama de flujo PRISMA. Se incluyeron artículos publicados en los últimos 10 años en inglés y español, centrados en intervenciones de estilo de vida y tratamientos farmacológicos para la prevención y control de HTA y DM2. En el análisis de estos estudios se destacó la importancia de las medidas antropométricas, como la circunferencia de la cintura, para evaluar la obesidad central, un significativo factor de riesgo. Se encontró que la modificación del estilo de vida, incluyendo una dieta saludable y la actividad física regular, es crucial para prevenir y controlar HTA y DM2. Además, se subrayó la necesidad de una intervención interdisciplinaria integral y la educación continua del paciente. En conclusión, el artículo resalta la importancia de una combinación de cambios en el estilo de vida y el uso de medicamentos para el manejo eficaz de HTA y DM2 contribuyendo así a las prevención y control de la hipertensión y la diabetes. La educación del paciente y su familia, junto con un enfoque multidisciplinario, son esenciales para optimizar la gestión de estas condiciones crónicas. El articulo permitirá la aplicación de conocimientos en asignaturas como salud pública y bioquímica y al proyecto de investigación titulado “Utilidad de Cistatina C en la disfunción renal e identificación de factores de riesgo: un camino hacia la medicina preventiva en habitantes de la ciudad de Jipijapa”, conjunto con el proyecto de vinculación denominado "Influencia del laboratorio clínico en la prevención y diagnóstico de la enfermedad renal en pacientes con diabetes mellitus e hipertensión arterial del sur de Manabí. Fase I.".
Proteomic profiling of oleamide-mediated polarization in a primary human monocyte-derived tumor-associated macrophages (TAMs) model: a functional analysis
Authors: Wisitpongpun Prapakorn , Buakaew Watunyoo , Pongcharoen Sutatip , Apiratmateekul Napaporn , Potup Pachuen , Daowtak Krai , Krobthong Sucheewin , Yingchutrakul Yodying , Brindley Paul J. , Usuwanthim Kanchana 
Published: September 2024

Background
Tumor-associated macrophages (TAMs) play a critical function in the development of tumors and are associated with protumor M2 phenotypes. Shifting TAMs towards antitumor M1 phenotypes holds promise for tumor immunotherapy. Oleamide, a primary fatty acid amide, has emerged as a potent anticancer and immunomodulatory compound. However, the regulatory effects of oleamide on TAM phenotypes remain unclear.

Methods
We used real-time quantitative reverse transcription polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA) techniques to study the influence of oleamide on primary human monocyte-derived TAM phenotypes, and we investigated the protein expression profiles based on mass spectrometry to analyze the effect of oleamide on macrophage polarization. Moreover, the advantageous binding scores between oleamide and these target candidate proteins are examined using molecular docking.

Results
Our study revealed that oleamide effectively suppressed the M2-like TAM phenotype by reducing interleukin (IL)-10 production and downregulating M2-like markers, including vascular endothelial growth factor A (VEGFA), MYC proto-oncogene, bHLH transcription factor (c-Myc), and mannose receptor C-type 1 (CD206). Moreover, the conditioned medium derived from oleamide-treated TAMs induces apoptosis of MDA-MB-231 breast cancer cells. Proteomic analysis identified 20 candidate up- and down-regulation proteins targeted by oleamide, showing modulation activity associated with the promotion of the M1-like phenotype. Furthermore, molecular docking demonstrated favorable binding scores between oleamide and these candidate proteins. Collectively, our findings suggest that oleamide exerts a potent antitumor effect by promoting the antitumor M1-like TAM phenotype. These novel insights provide valuable resources for further investigations into oleamide and macrophage polarization which inhibit the progression of breast cancer, which may provide insight into immunotherapeutic approaches for cancer.
Gestão por competências na administração pública brasileira: um estudo bibliométrico no período de 2018 a 2022
Authors: Barreto Laís Karla da Silva , Silva Allan Gustavo Freire da , Mendes Andrhea Carneiro , Adriano Islayne Teixeira , Moura Marcelo Giovanni Correia 
Published: September 2024

O presente trabalho é uma revisão de literatura do tipo bibliométrico, analisando a produção acadêmica publicada sobre gestão por competências no setor público brasileiro. A pesquisa foi conduzida nas bases de dados World Wide Science, Spell e Periódicos Capes, com recorte temporal de 2018 a 2022, utilizando o termo de busca gestão por competências na administração pública. Este artigo apresenta natureza aplicada e quantitativa. A pesquisa foi conduzida por meio de análise de conteúdo considerando aspectos como ano de publicação, autores, periódicos, região do autor, Estados de aplicação da pesquisa, Instituição do autor, Esfera (municipal, estadual ou federal) e área de atuação (educação, saúde, justiça, financeiro, administração e meio ambiente). Após aplicação dos filtros, foram selecionados 29 trabalhos para detalhamento. A partir dos artigos selecionados, foi possível perceber que a análise bibliométrica realizada neste estudo oferece uma visão abrangente da produção científica relacionada ao tema Gestão por Competências que pertence à área de gestão de pessoas no contexto organizacional da Administração Pública Brasileira. Os resultados demonstram que o interesse pelo tema permaneceu estável durante o período, com uma leve queda em 2020, mas retornou ao padrão em 2022. Ao explorar as tendências, lacunas e padrões emergentes, este trabalho visa contribuir para uma compreensão mais profunda do impacto da gestão de pessoas nas organizações públicas, destacando sua importância contínua em ambientes dinâmicos e em constante evolução.
Holistic Review on Mushroom: A Perspective on Production, Economics, Marketing and Constraints in India
Authors: Pandya Maitrak R. , Vahoniya Dilip R. , Rajwadi Alvira 
Published: September 2024

Mushroom cultivation offers humongous potential to improve socio-economical condition of farmers and strengthen food security of world since it serves as utilization of agricultural wastes and offering mushroom and manure from used substrate. It becomes important part at global level due to increasing demand of mushroom. It provides livelihood to most of small and marginal farmers of Bihar, Maharashtra, Odisha and other temperate region of country. For Mushroom cultivation require labor on the daily basis so it provide employment in rural area and it is providing typical management and economical advantages over other allied sector in agriculture. This article provides a chronological study of different research articles published from the year 2013-2024. The present article provides a theme and pattern on which research was conducted and it can be classified into five categories that is socio-economic conditions of growers, production, economic analysis, marketing scenario & value chain and constraints face by growers. The finding indicates that mushroom entrepreneurship is to great extent a metropolitan or semi-metropolitan undertaking. Post-harvest losses can be reduced by providing training and adopting different value addition methods at production level. It requires concentration on various marketing strategies for spread awareness about nutrition content and increasing in demand. Thus, value addition and marketing strategies can help in export of mushroom to earn foreign revenue.
A Systematic Review Analysis on Instructional Leadership Styles: Exploring Research Foci, Conceptual Models, Methodological Designs, and Geographical Distributions
Authors: Paring Ian Reggy B. 
Published: September 2024

Aims: This study explored the various literature on Instructional leadership of secondary school principals. This study aimed to answer the following questions based on (1) the geographic distribution of the distributed leadership literature published globally; (2) methodological designs (qualitative, quantitative, mixed methods) have been adopted and data collection tools used; (3) the nature of literature in terms of research foci; and (4) conceptual frameworks/models are predominant in the relevant literature publications between 2012 and 2022.
Study Design: Systematic review analysis.
Place and Duration of Study: The systematic review of existing literature was carried-out last 2023 and analyzed relevant studies on instructional leadership from 2012-2022.
Methodology: This study utilized the systematic review analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) as the functional research design in answering the research questions. The study used the Google scholar and Eric as the main database search platform for seeking relevant literature. These databases have an advanced search method to set the desired operative words, the year of publication, and it provides the data based such as in-full text version, peer-reviewed, written in English, research design, etc.
Results: As a result of the systematic analysis, this study exposed notable variations in terms of research design employed, and the locale of the study. Based on the synthesis of the various research studies, it was observed that instructional leadership is currently being studied against students, teachers, and school performances. Moreover, the widely used conceptual framework used was exploratory, and a direct effect model.
Conclusion: Finally, the framework provided by this study and the overview of the challenges outlined here may help to improve the delivery of instructional leadership among secondary school principals and will serve as the foundation for future research projects and policy decisions.
Adoption of Cold Reeling as a tool of Selection in the Breeding of “Nistari”: A Multivoltine Breed of Mulberry Silkworm (Bombyx. mori) in West Bengal, India
Authors: Devi Thangjam Ranjita , Chakrabarty Satadal , CM Kishor Kumar 
Published: September 2024

Mulberry silkworm (B. mori) is an economic insect reared for silk. Economic traits of silkworm are highly influenced and deteriorated by fluctuating environmental conditions arising due to global warming. Artificial selection has always played a crucial role in silkworm domestication to improve economic traits. Filament length is important from the perspective of mulberry sericulture. Nistari lines (“Marked” and “Plain”) which is a ruling multivoltine breed in West Bengal, India, have short filament length and economic traits are observed to be deteriorated. Selection of parents with high filament length is hard as the pupa corresponding with higher filament length is sacrificed during the process of reeling in hot temperature in conventional reeling. “Cold reeling is an alternative reeling, devoid of hot temperature, thereby enabling the rescue of pupae for further metamorphosis. Cold reeling can be adopted to select parents with higher filament lengths in mulberry silkworm for successive generations. The present study attempted to increase the filament length of “Marked” and “Plain” lines of Nistari, by selecting parents with high filament length for six consecutive generations by implementing cold reeling. A gradual increase in filament length was observed, in both the Nistari lines over six generations. This approach could enhance the economic value of Nistari silkworms and may be applicable to other breeds, potentially boosting silk production in West Bengal."
Determinants of Infertile of Infertile Women Requesting Assisted Reproduction Techniques in a Low Resource Setting in Western Nigeria
Authors: SI Omisakin , AO Ugwu , JA Olamijulo , CC Makwe , AA Oluwole , OA Kusamotu , OA Fagbolagun , KM Lemomu , TP Adejumo , TI Opemuade , OD Martin-Akinlose , A Awoniyi , OK Ogedengbe , OF Giwa-Osagie 
Published: September 2024

Background: Infertility is an important gynaecological condition with psycho-social, cultural, economic, religious, demographic, and clinical consequences. Although the prevalence of couples having problems with conception has remained relatively stable worldwide, there has been an increase in the proportion of couples seeking fertility services. This substantial increase might reflect the improvement in the advancements in fertility care, improved success rates, increased availability of specialists and or involvement of insurance firms in infertility treatment. Paradoxically, countries in Africa with high infertility burden still lags in fertility care. This study was therefore aims to investigate the types and causes of infertility in patients attending fertility care in an assisted conception Centre in a public tertiary hospital in southwest Nigeria.
Methods: This was a retrospective study of patient records who attended Assisted fertility centre (AFC) of Lagos University Teaching Hospital (LUTH), from January 1st, 2015, to December 31st, 2023. Categorical variables were analysed using percentages while continuous variables were analysed using mean and standard deviation and the association between categorical variables was analysed using chi-square test. The statistical significance level was set at p-value < 0.05.
Results: The mean age and mean duration of infertility of the participants in the study was 40.89±6.8, and 8.14±3.5 respectively. About 72.9% had more than secondary education while almost two thirds of the participants had secondary infertility, 36.1% had previous pelvic surgeries, 11.4% had chronic pelvic pain and menstrual abnormality. Secondary infertility was more prevalent in women who has chronic pelvic pain, or those who has had previous pelvic surgery, previous infertility or previous abortion.
Conclusion: In conclusion our analysis suggests that Secondary infertility is the commonest cause of inability to conceive in our facility. It also revealed that most of our women present late for fertility care at an advanced maternal age.
Screening of Tomato (Solanum lycopersicum) Germplasm against Fusarium Wilt and Tomato Leaf Curl Virus Diseases in Naturally Ventilated Polyhouse
Authors: K Sairam , K Gopal , B Srinivasulu , Ch Ruth , P Rama Devi , M Ravindra Babu , V Padmaja 
Published: September 2024

Aims: Screening of tomato germplasm against fusarium wilt and tomato leaf curl virus diseases in naturally ventilated polyhouse.
Place and Duration of Study: The experiment was conducted during rabi 2020-2021 under naturally ventilated poly house, which located at Center of Excellence, Dr. Y.S.R. Horticultural University, Venkataramannnagudem.
Methodology: Total 21 tomato genotypes which included 18 germplasm lines and 3 commercial cultivars as a check (Arkavikas, Polyana and BSS 1006) collected from the HRS, Venkataramannagudem which were screened against major diseases of tomato under naturally ventilated polyhouse and to find out resistance source.
Results: Among the 21 genotypes screened against tomato leaf curl virus lowest per cent disease incidence was recorded in VRSL (Venkataramannagudem Solanum lycopersicum) -114 (5.88 %), VRSL-134 (6.54 %) and VRSL-136 (6.86 %). Highest per cent disease incidence was recorded in Arka vikas (17.87 %). Among the 21 genotypes screened lowest per cent disease incidence was recorded in VRSL -40 and VRSL-134 (9.79 %). Highest per cent disease incidence was recorded in A.vikas (32.28 %).
Politische Äußerungen von Vorstandsmitgliedern
Authors: Wedemann Frauke 
Published: September 2024

Zusammenfassung
Wie viel politische Meinung kann sich ein Geschäftsleiter erlauben? Dieser Frage kommt angesichts des zunehmenden Trends zu „CEO Activism“ mittlerweile auch in Deutschland erhebliche Relevanz zu. Ihr rechtlicher Rahmen ist allerdings noch wenig ausgearbeitet. Der folgende Beitrag unternimmt es, die Zulässigkeit politischer Äußerungen von AG-Vorstandsmitgliedern auszuloten. Er entwickelt allgemeine Kriterien für die Beurteilung der Zulässigkeit und konkretisiert diese anhand von Fallgruppen.
Das neue KapMuG – Reform mit Licht und Schatten
Authors: Sustmann Marco , Retsch Alexander 
Published: September 2024

Zusammenfassung
Die Mitte Juli 2024 in Kraft getretene Reform des Kapitalanleger- Musterverfahrensgesetzes (KapMuG) soll kapitalmarktrechtliche Masseverfahren effizienter gestalten. Wichtige Neuerungen sind die Ausweitung des Anwendungsbereichs, die Stärkung der Rolle der OLG sowie Adjustierungen beim Maßstab für die Aussetzung der Ausgangsverfahren. Neu ist auch die Möglichkeit, die Vorlage von Beweismitteln durch die Gegenseite zu beantragen. Dieser Beitrag beleuchtet diese Neuerungen und unterzieht sie einer ersten Bewertung.
Die Nachspaltungsveräußerungssperre nach dem Wachstumschancengesetz — Ist der holprige Name Programm?
Authors: Mayer Vivien , Käshammer Daniel 
Published: September 2024

Zusammenfassung
Das Wachstumschancengesetz enthält umfangreiche Anpassungen im Bereich der Missbrauchstatbestände bei Abspaltungen nach § 15 Abs. 2 Satz 2 ff. UmwStG, insbesondere bei der sog. Nachspaltungsveräußerungssperre. In Teilen handelt es sich dabei um eine Nichtanwendungsgesetzgebung zu einem im Januar 2022 veröffentlichten BFH-Urteil, nach dem einer Spaltung nachfolgende Veräußerungen unterhalb der 20-%-Grenze oder nach Ablauf der Fünfjahresfrist unschädlich gewesen wären. Diese Fälle sollen unter der neuen Rechtslage nicht mehr steuerneutral möglich sein. Die Neuregelung ist dabei sehr komplex und erneut auslegungsbedürftig ausgestaltet. Auch die rückwirkende Anwendungsregelung ist kritisch zu bewerten, da sie zuungunsten der Steuerpflichtigen unter Umständen in bereits verwirklichte Spaltungen eingreift. Im vorliegenden Beitrag sollen insbesondere Herausforderungen in der Praxis (Auslegungsfragen und Fallbeispiele) näher beleuchtet werden, z.B. Auslegungsfragen der neuen Legaldefinition des § 15 Abs. 2 Sätze 3 und 7 UmwStG n.F. und in Zusammenhang mit der neuen „Wertverschiebungs-Escape-Klausel“ nach § 15 Abs.2 Satz 6 UmwStG n.F
Seismogenic stress field estimation in the Calabrian Arc region (south Italy) from a Bayesian approach
Authors: Totaro C. , Orecchio B. , Presti D. , Scolaro S. , Neri G. 
Published: August 2016

AbstractA new high‐quality waveform inversion focal mechanism database of the Calabrian Arc region has been compiled by integrating 292 mechanisms selected from literature and catalogs with 146 newly computed solutions. The new database has then been used for computation of posterior density distributions of stress tensor components by a Bayesian method never applied in south Italy before the present study. The application of this method to the enhanced database has allowed us to provide a detailed picture of seismotectonic stress regimes in this very complex area where lithospheric unit configuration and geodynamic engines are still strongly debated. Our results well constrain the extensional domain of Calabrian Arc and the compressional one of the southernmost Tyrrhenian Sea. In addition, previously undetected transcurrent regimes have been identified in the Ionian offshore. The new information released here will furnish useful tools and constraints for future geodynamic investigations.