bluuebunny/crossref_metadata_2025_split huggingface dataset:
Widespread sampling biases in herbaria revealed from large-scale digitization
Authors: Daru Barnabas H. , Park Daniel S. , Primack Richard B. , Willis Charles G. , Barrington David S. , Whitfeld Timothy J. S. , Seidler Tristram G. , Sweeney Patrick W. , Foster David R. , Ellison Aaron M. , Davis Charles C. 
Published: July 2017

SUMMARYNon-random collecting practices may bias conclusions drawn from analyses of herbarium records. Recent efforts to fully digitize and mobilize regional floras offer a timely opportunity to assess commonalities and differences in herbarium sampling biases.We determined spatial, temporal, trait, phylogenetic, and collector biases in ∼5 million herbarium records, representing three of the most complete digitized floras of the world: Australia (AU), South Africa (SA), and New England (NE).We identified numerous shared and unique biases among these regions. Shared biases included specimens i) collected close to roads and herbaria; ii) collected more frequently during spring; iii) of threatened species collected less frequently; and iv) of close relatives collected in similar numbers. Regional differences included i) over-representation of graminoids in SA and AU and of annuals in AU; and ii) peak collection during the 1910s in NE, 1980s in SA, and 1990s in AU. Finally, in all regions, a disproportionately large percentage of specimens were collected by a few individuals. These mega-collectors, and their associated preferences and idiosyncrasies, may have shaped patterns of collection bias via ‘founder effects’.Studies using herbarium collections should account for sampling biases and future collecting efforts should avoid compounding these biases.
Resources and capabilities’ effects on firm performance: what are they?
Authors: Ferreira João , Fernandes Cristina 
Published: July 2017

PurposeThe purpose of this paper is to empirically examine the moderating effect of competitive advantage on the resource value and rareness combination and firm performance.Design/methodology/approachThe authors adopted a quantitative research method to achieve the aims of this study. The data collected came from a sample of footwear firms and the hypotheses assessed by multivariate analysis.FindingsThe findings provide insights into previously inconsistent findings regarding the exploitation of resources and capabilities and contribute to resolving these issues by considering the conditions under which the resource value and rareness combination contributes to firm performance levels and the effects of competitive advantage on this relationship. Interestingly, the authors find that it cannot be inferred that the rarer the resources and capabilities combination, the greater the probability of attaining competitive advantage.Research limitations/implicationsAs limitations, the authors would highlight the fact that the results are specific to one particular industrial sector, and thus not susceptible to the drawing of generalisations as well as the fact that the study does not make recourse to triangulating its methodology (for example, through interviews), which would generate more precise, detailed and objective information. The findings have important managerial implications and the authors close by presenting future research directions.Originality/valueThis study offers an explanation for previous mixed findings on the relationship between the resource value and rareness combination and firm performance and makes a contribution regarding how such combinations are of great relevance to the organisation and business strategy to turn in better performance levels.
Creating an interface
Authors: Prieto Leon C. , Phipps Simone T.A. , Osiri John K. , LeCounte John F. 
Published: July 2017

Purpose
This paper, via the use of management and entrepreneurial philosophies from Charles Clinton Spaulding, aims to advocate the integration of African-American Entrepreneurship and Management History into the business curriculum at historically black colleges and universities (HBCUs) as well as predominantly white institutions (PWIs). Along with this curriculum update, the use of critical pedagogy as a form of critical thinking is also recommended to complement the learning process.

Design/methodology/approach
Articles from early and recent newspapers, magazines, journals and books were examined and synthesised to clarify how curriculum modification and critical pedagogy could aid in increased entrepreneurial success.

Findings
The paper concludes with a framework that demonstrates the curriculum interface, including Spaulding’s insights and critical pedagogy, to connect black students to entrepreneurial success.

Originality/value
Although African-Americans surpass Caucasian-Americans in entrepreneurial attempts, blacks lag behind whites in entrepreneurial success. A reason for their higher failure rate is a lack of exposure to positive images who are also black. Integrating African-American Entrepreneurship and Management History into the business curriculum will help ensure that these positive images are sufficiently introduced and explored as a source of learning. Critical pedagogy is also endorsed as a complementary strategy to aid learning, as it is associated with processes that deviate from traditional instruction that often ignores student diversity, to facilitate the expansion of the mind as well as social transformation.
The changing relation between CEOs and shareholders
Authors: de Jong Abe , van der Poel Marieke , Wolfswinkel Michiel 
Published: July 2017

PurposeThis paper aims to present case study evidence on the changes in the relations between chief executive officers (CEOs) of large firms and shareholders in the past three decades of the twentieth century. In line with insights from agency theory, the CEOs have experienced increased scrutiny from their principals, the shareholders. This development has affected financial communication and investor relations as well as stock market prices.Design/methodology/approachThe Dutch electronics firm Royal Philips NV in the transition period of 1971-2001 has been studied using publicly available disclosures and stock market prices. A descriptive case study approach is combined with event study methodology.FindingsIt was observed that the increased emphasis on shareholder interests has affected the interactions between Philips’ respective CEOs and the shareholders’ reactions to strategic decisions as measured by stock price changes. Around the beginning of the twenty-first century, clarity and openness in CEO communication was the norm and deviations were punished with volatile stock prices.Research limitations/implicationsThe study relies on publicly available data.Originality/valueThe case study of Philips can be extrapolated to other exchange-listed firms in the late twentieth century, which faced changed expectations about the role of the CEO, investor relations and the CEO’s accountability toward shareholders. This transition is relevant not only as a historical observation, but also as a background to studies in finance and management about top management and financial markets.
Failure processes of exporting firms: evidence from France
Authors: Lukason Oliver , Vissak Tiia 
Published: July 2017

PurposeThis paper aims to detect failure processes of French exporting firms and study their contingency with export processes.Design/methodology/approachThe sample consisted of 131 bankrupted exporting firms from Bureau van Dijk’s Amadeus database. Factor and cluster analyses of six financial variables from Laitinen’s (1991) model were used to detect failure processes. Export processes were detected with cluster analysis of export share in total turnover. Contingency between failure and export processes was studied with a statistical test.FindingsThree different failure processes existed for exporting firms. Two of these processes, which accounted for 79 per cent of firms, were classified as gradual failure: a step-by-step worsening of financial performance before the bankruptcy was declared. One was a symbiotic process reflecting varying pre-bankruptcy behaviours of different financial variables. Two different types of exporters existed. Most firms (77 per cent) were occasional exporters, while 23 per cent were constantly and more strongly involved in international markets before their bankruptcy was declared. There was no contingency between failure and export processes.Originality/valueThis study is the first one to detect failure processes specifically for exporting firms based on financial variables. In line with previous literature about non-exporting firms, gradual failure processes were most characteristic to exporting firms. The study shows that different types of exporters were not characterized by any unique behaviour of financial variables before their bankruptcy was declared.
Evaluation of intralesional injection of hyaluronic acid compared with verapamil in Peyronie's disease: preliminary results from a prospective, double‐blinded, randomized study
Authors: Favilla V. , Russo G. I. , Zucchi A. , Siracusa G. , Privitera S. , Cimino S. , Madonia M. , Cai T. , Cavallini G. , Liguori G. , D'Achille G. , Silvani M. , Franco G. , Verze P. , Palmieri A. , Torrisi B. , Mirone V. , Morgia G. 
Published: July 2017

SummarySeveral intralesional therapeutic protocols have been proposed for the treatment of Peyronie's disease. Among all, hyaluronic acid (HA) and verapamil have been differently tested. We aimed to evaluate the efficacy of intralesional verapamil (ILVI) compared with intralesional HA in patients with early onset of Peyronie's disease (PD). This is a multi‐centre prospective double‐arm, randomized, double‐blinded study comparing ILVI vs. intralesional HA after 12‐weeks. Sexually active men, older than 18 years and affected by the acute phase of PD were eligible for this study. Patients have been double‐blinded randomly divided into two groups (1 : 1 ratio): Group A received intralesional treatment with Verapamil (10 mg in 5 mL of normal saline water) weekly for 12 weeks, while group B received intralesional treatment with HA (0.8% highly purified sodium salt HA 16 mg/2 mL) weekly for 12 weeks. The primary efficacy outcome was the change from the baseline to the endpoint (12 weeks after therapy) for the penile curvature (degree). The secondary outcome was the change in the plaque size and in the International Index of erectile Function (IIEF‐5) score. The difference between post‐ and pre‐treatment plaque size was −1.36 mm (SD ± 1.27) for Group A and −1.80 mm (SD ± 2.47) for Group B (p‐value = NS). IIEF‐5 increased of 1.46 points (SD ± 2.18) in Group A and 1.78 (SD ± 2.48) in Group B (p‐value ± NS). No difference in penile curvature was observed in Group A, while in Group B the penile curvature decreased of 4.60° (SD ± 5.63) from the baseline (p < 0.001) and vs. Group A. According to PGI‐I results, we found significant difference as concerning patient global impression of improvement (PGI‐I) (4.0 vs. 2.0; p < 0.05). This prospective, double‐arm, randomized, double‐blinded study comparing ILVI vs. HA as intralesional therapy showed greater efficacy of HA in terms of penile curvature and PGI‐I.
Next‐generation sequencing for patients with non‐obstructive azoospermia: implications for significant roles of monogenic/oligogenic mutations
Authors: Nakamura S. , Miyado M. , Saito K. , Katsumi M. , Nakamura A. , Kobori Y. , Tanaka Y. , Ishikawa H. , Yoshida A. , Okada H. , Hata K. , Nakabayashi K. , Okamura K. , Ogata H. , Matsubara Y. , Ogata T. , Nakai H. , Fukami M. 
Published: July 2017

SummaryAzoospermia affects up to 1% of adult men. Non‐obstructive azoospermia is a multifactorial disorder whose molecular basis remains largely unknown. To date, mutations in several genes and multiple submicroscopic copy‐number variations (CNVs) have been identified in patients with non‐obstructive azoospermia. The aim of this study was to clarify the contribution of nucleotide substitutions in known causative genes and submicroscopic CNVs in the genome to the development of non‐obstructive azoospermia. To this end, we conducted sequence analysis of 25 known disease‐associated genes using next‐generation sequencing and genome‐wide copy‐number analysis using array‐based comparative genomic hybridization. We studied 40 Japanese patients with idiopathic non‐obstructive azoospermia. Functional significance of molecular alterations was assessed by in silico analyses. As a result, we identified four putative pathogenic mutations, four rare polymorphisms possibly associated with disease risk, and four probable neutral variants in 10 patients. These sequence alterations included a heterozygous splice site mutation in SOHLH1 and a hemizygous missense substitution in TEX11, which have been reported as causes of non‐obstructive azoospermia. Copy‐number analysis detected five X chromosomal or autosomal CNVs of unknown clinical significance, in addition to one known pathogenic Y chromosomal microduplication. Five patients carried multiple molecular alterations. The results indicate that monogenic and oligogenic mutations, including those in SOHLH1 and TEX11, account for more than 10% of cases of idiopathic non‐obstructive azoospermia. Furthermore, this study suggests possible contributions of substitutions in various genes as well as submicroscopic CNVs on the X chromosome and autosomes to non‐obstructive azoospermia, which require further validation.
Impairment of sperm DNA methylation in male infertility: a meta‐analytic study
Authors: Santi D. , De Vincentis S. , Magnani E. , Spaggiari G. 
Published: July 2017

SummaryConsidering the widespread use of assisted reproductive techniques (ART), DNA methylation of specific genes involved in spermatogenesis achieves increasingly clinical relevance, representing a possible explanation of increased incidence of syndromes related to genomic imprinting in medically assisted pregnancies. Several trials suggested a relationship between male sub‐fertility and sperm DNA methylation, although its weight on seminal parameters alteration is still a matter of debate. To evaluate whether aberrant sperm DNA methylation of imprinted genes is associated with impaired sperm parameters. Meta‐analysis of controlled clinical trials evaluating imprinted genes sperm DNA methylation comparing men with idiopathic infertility to fertile controls. Twenty‐four studies were included, allowing a meta‐analytic evaluation for H19, MEST, SNRPN, and LINE‐1. When a high heterogeneity of the results was demonstrated, the random effect model was used. H19 methylation levels resulted significantly lower in 879 infertile compared with 562 fertile men (7.53%, 95% CI: 5.14–9.93%, p < 0.001), suggesting a 9.91‐fold higher risk ratio to show aberrant sperm DNA methylation (95% CI: 5.55–17.70, p < 0.001, I2 = 19%) in infertile men. The mean MEST methylation level was significantly higher in 846 infertile compared with 353 fertile men (3.35%, 95% CI: 1.41–5.29%, p < 0.001), as well as for SNRPN comparing 301 infertile men with 124 controls (3.23%, 95% CI: 0.75–5.72%, p < 0.001). LINE‐1 methylation levels did not differ between 291 infertile men and 198 controls (0.44%, 95% CI: −2.04–1.16%, p = 0.63). The meta‐analytic approach demonstrated that male infertility is associated with altered sperm methylation at H19, MEST, and SNRPN. Although its role in infertility remains unclear, sperm DNA methylation could be associated with the epigenetic risk in ART. In this setting, before proposing this analysis in clinical practice, an accurate identification of the most representative genes and a cost‐effectiveness evaluation should be assessed in ad hoc prospective studies.
Development of Public Housing in Post‐reform China
Authors: Chen Jie , Yao Lingzhen , Wang Hongwei 
Published: July 2017

AbstractThis paper explores the dynamic nature of the transformation of public housing regimes in urban China since the abolishment of the urban welfare housing system in the late 1990s. We summarize the latest progress in the development of public housing in post‐reform China and investigate the driving forces behind these developments. A close examination of the public rental housing program in Shanghai helps to show that the recent revival of public housing in Chinese cities is mostly driven by the desire for economic growth. We conclude that the state provision of housing could be a short‐run state remedy to alleviate economic imbalance and social inequality. However, in the long run China needs to seek more effective solutions to solve the low‐income population's housing affordability problems.
Digital Subtraction Angiography‐Dynavision in Pretreatment Planning for Embolization of Dural Arterio‐Venous Fistulas
Authors: Botsford Alex , Shankar Jai Jai Shiva 
Published: July 2017

ABSTRACTBACKGROUND AND PURPOSEWe have found DSA‐Dynavision with multiplanar reconstruction very helpful in understanding the complex anatomy and planning of treatment of carotico‐cavernous fistulas. The purpose of our study was to examine whether using DSA‐Dynavision in pretreatment planning results in better outcome after endovascular treatment of dural arterio‐venous fistulas (dAVFs).METHODSPatients with dAVF treated with endovascular embolization were retrospectively identified from our interventional neuroradiology database. Patients were assessed and divided into those with DSA‐Dynavision and those without. They were compared for procedural time, angiographic evidence of cure, rates of resolution of cortical venous reflux (CVR), complications, and need for postembolization surgery.RESULTSEighty‐six percent of 28 patients (mean age 57 years, range 1.67‐84 years) had Borden type 3 DAVF; 7% had Borden type 2; and 7% had Borden type 1. DSA‐Dynavision was used in 14 of 28 (50%) patients. Fewer patients with DSA‐Dynavision required postendovascular embolization surgery (7% vs. 50%, P = .01) and fewer DSA‐Dynavision patients had CVR postprocedure (29% vs. 71%, P = .023). Mean procedural time (207 vs. 249 minutes; P = .40); permanent neurological complication rates (7% vs. 7%, P = 1.0); rate of immediate angiographic occlusion (64% vs. 29%, P = .061), and reported resolution of symptoms (79% vs. 53%, P = .18) were not significantly different. There was no significant difference in follow‐up (mean: 75 vs 120 weeks, P = .47).CONCLUSIONThe use of DSA‐Dynavision in planning of endovascular treatment of dAVF is associated with higher rates of elimination of CVR and less need for postembolization surgery.
An MRI Hyperintense Acute Reperfusion Marker Is Related to Elevated Peripheral Monocyte Count in Acute Ischemic Stroke
Authors: Nadareishvili Zurab , Luby Marie , Leigh Richard , Shah Jignesh , Lynch John K. , Hsia Amie W. , Benson Richard T. , Latour Lawrence L. 
Published: July 2017

ABSTRACTBACKGROUND AND PURPOSEBlood–brain barrier (BBB) disruption detected on magnetic resonance imaging (MRI) in acute ischemic stroke as a hyperintense acute reperfusion marker (HARM) is associated with upregulation of matrix metalloproteinase‐9 (MMP‐9). Although activated leukocytes, including monocytes, are the main source of MMPs, limited data exist to support relationship between leukocyte activation and BBB disruption in patients with acute ischemic stroke. The goal of this study is to investigate the relationship between neutrophils, lymphocytes, and monocytes with BBB disruption detected as HARM (+) in patients with acute ischemic stroke.METHODSWe conducted a retrospective analysis of prospectively collected data in patients who did not receive any reperfusion therapy with acute (<12 hours) ischemic stroke. MRI scans were obtained at baseline, 24 hours, and 5 days. HARM was evaluated on the 24‐hour follow‐up scan.RESULTSThirty‐three patients were studied. HARM was detected in 27% of patients. Median volumes of baseline perfusion (mean transit time [MTT]) deficit (219.4 mL vs. 158.4 mL, P = .029) and DWI infarct growth at 24 hours (18.50 mL vs. .14 mL, P = .017), as well as the median absolute numbers (1 × 103/mm3) of monocytes, were significantly higher in HARM (+) versus HARM (−) patients (0.9 vs. 0.6, p = 0.011).CONCLUSIONIncreased monocyte count associated with HARM supports importance of systemic inflammation in BBB disruption in acute ischemic stroke.
Modified Voltage Control Law for Low Frequency Railway Power Systems
Authors: Laury John , Abrahamsson Lars , Bollen Math 
Published: July 2017

In today’s Swedish and Norwegian low frequency railway power system the voltage at a converter is controlled such that its voltage will drop with increased reactive power output. However, for low frequency railways the influence of active power on voltage is larger compared to public power systems and alternative methods are interesting to investigate.
This paper presents a modified voltage control law for increased load sharing between converter stations and reduce the risk for converter overload in low frequency railways power systems. The modified voltage control law is derived mathematically and tested with different droops for two case studies. The results confirms the increased load sharing between the converter stations.
The results are analysed and discussed; ideas are presented to counteract some of the negative impacts of the modified voltage control law.
Incorporating Life Cycle Assessment (LCA) in Freight Transportation Infrastructure Project Evaluation
Authors: Oduru Soumith Kumar , Lautala Pasi 
Published: July 2017

Transportation industry at large is a major consumer of fossil fuels and contributes heavily to the global greenhouse gas emissions. A significant portion of these emissions come from freight transportation and decisions on mode/route may affect the overall scale of emissions from a specific movement. It is common to consider several alternatives for a new freight activity and compare the alternatives from economic perspective. However, there is a growing emphasis for adding emissions to this evaluation process. One of the approaches to do this is through Life Cycle Assessment (LCA); a method for estimating the emissions, energy consumption and environmental impacts of the project throughout its life cycle.
Since modal/route selections are often investigated early in the planning stage of the project, availability of data and resources for analysis may become a challenge for completing a detailed LCA on alternatives. This research builds on such detailed LCA comparison performed on a previous case study by Kalluri et al. (2016), but it also investigates whether a simplified LCA process that only includes emissions from operations phase could be used as a less resource intensive option for the analysis while still providing relevant outcomes. The detailed LCA is performed using SimaPro software and simplified LCA is performed using GREET 2016 model. The results are obtained in terms of Kg CO2 equivalents of GHG emissions. This paper introduces both detailed and simplified methodologies and applies them to a case study of a nickel and copper mine in the Upper Peninsula of Michigan. The analysis’ are done for three modal alternatives (two truck routes and one rail route) and for multiple mine lives.
Neurotoxic Concentration of Piperacillin during Continuous Infusion in Critically Ill Patients
Authors: Quinton Marie-Charlotte , Bodeau Sandra , Kontar Loay , Zerbib Yoann , Maizel Julien , Slama Michel , Masmoudi Kamel , Lemaire-Hurtel Anne-Sophie , Bennis Youssef 
Published: July 2017

ABSTRACT
This retrospective cohort study included 53 patients admitted to the intensive care unit (ICU), with an average age of 69 years, without neurologic disorder before initiation of a continuous piperacillin infusion at the standard dose and who underwent piperacillin serum concentration monitoring. Among them, 23 developed a neurologic disorder for which the piperacillin causality was chronologically and semiologically suggestive. A concentration threshold of 157.2 mg/liter independently predicted neurotoxicity with 96.7% specificity and 52.2% sensitivity and may constitute a limitation when targeting less susceptible pathogens.