bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Performance Indicator Development: A Study at The Ministry of Foreign Affairs of The Republic of Indonesia
Authors: Andari Nestri Retno , Akbar Rusdi 
Published: September 2024

Research aims: This study evaluates the development of performance indicators using the performance blueprint analysis tool and determines the institutional factors that play a role in the development of performance indicators.
Design/Methodology/Approach: Qualitative research with a case study approach was conducted at the Indonesian Ministry of Foreign Affairs.
Research findings: The Ministry of Foreign Affairs' performance indicator development has applied the principle of logical flow so that the programs and activities set have supported the strategic goals. In addition, most of the performance indicators include results and quality-oriented. However, weak documentation means that the logic flow is not well illustrated. This research captures the phenomena of isomorphism (coercive, mimetic, and normative), institutional logic, and institutional entrepreneurship in the performance measurement system (including the development of performance indicators) at the Ministry of Foreign Affairs. In addition, 15 institutional factors play a role in the development of performance indicators in the Ministry of Foreign Affairs, namely external parties, institutional idealism, initiation, efforts (related to accountability and performance indicator development), human resources, mindset, documentation, monitoring and evaluation (M&E), leadership commitment, logical framework principles, the role of stakeholders, business processes, reward and punishment, training, and information systems.
Theoretical contribution/Originality: This research complements knowledge related to evaluating the development of performance indicators with performance blueprint analysis and institutional factors that play a role in the development of performance indicators, as well as knowledge about the phenomenon of institutional isomorphism, logic and entrepreneurship in government agencies.
Practitioner/Policy implication: Ministries/agencies and regulatory agencies can use the performance blueprint analysis tool so that they can develop appropriate indicators and support policy making.
Research limitation/Implication: The research focused only on the Ministry of Foreign Affairs, so the results do not reflect the development of performance indicators in other government agencies. In addition, the interviews did not take the point of view of external parties who have a relationship with the development of performance indicators of the Ministry of Foreign Affairs.
Korpusy tekstów w leksykografii jednojęzycznej i przekładowej czesko-polskiej
Authors: Charciarek Andrzej 
Published: September 2024

Artykuł poświęcony jest roli danych korpusowych w leksykografii jednojęzycznej i przekładowej. Ich wykorzystanie może w istotny sposób wpłynąć na budowę artykułu hasłowego w słowniku jednojęzycznym i przekładowym, czego dowodem jest analiza czeskiej jednostki leksykalnej klika. Przeprowadzona analiza pokazała możliwości opisu znaczenia jednostki za pomocą korpusu jednojęzycznego i wskazanie jej obcojęzycznych ekwiwalentów z wykorzystaniem korpusu równoległego. Tekst posłuży do głębszej refleksji nad tworzeniem siatki hasłowej, formy artykułu hasłowego i kryteriów ustanawiania par przekładowych.
Nazwy Gra komputerowa, Gra wideo, Gra cyfrowa w polszczyźnie. Analiza semantyczno-pragmatyczna
Authors: Kaszewski Krzysztof 
Published: September 2024

Celem artykułu jest opis i porównanie charakterystyk językowo-komunikacyjnych trzech najogólniejszych nazw GRY WIDEO w polszczyźnie. Główne źródła danych stanowiły słowniki języka polskiego, Narodowy Korpus Języka Polskiego oraz przekazy pochodzące z mediów wyspecjalizowanych zajmujących się grami wideo. Badania wykazały, że analizowane jednostki różnią się znaczeniem słowotwórczym i realnym, łączliwością znaczeniową oraz częstością występowania w dyskursie i zasięgiem społecznym.
The Effect of Teachers' Level of Self-Regulated Learning and Internet Self-Efficacy on Teaching Innovation in the Constructivist Curriculum
Authors: Budhi Santosa Eka , Sukmawati Fatma , Juwita Ratna , Prihatin Relly , Tri Cahyono Budi , Suparmi  
Published: September 2024

In the era of modern education, innovation in teaching is a crucial aspect for improving learning quality. This study aims to find out the extent to which Internet Self-Efficacy (ISE) of teachers affects learning innovation in the constructivist curriculum and the extent to which Self-Regulated Learning (SRL) affects teachers in making learning innovations in the constructivist curriculum. The research method used is quantitative with a survey approach. Data was collected through a questionnaire filled out by 97 junior high school teachers in Central Java who implemented a constructivist curriculum. Based on the results of the regression analysis, it was found that in the condition that teachers have a high level of Internet self-efficacy, self-regulated learning (SRL) has a significant effect on the learning innovations that are carried out by teachers. Another condition is the influence of SRL with low teacher ISE on teacher learning innovation. In the condition of low self-efficacy levels, SRL indicators of metacognitive skills, time management, and environmental settings did not have a significant effect on teachers' learning innovation. These findings indicate that teachers with high levels of self-regulated learning (SRL) and internet self-efficacy tend to be more innovative in implementing teaching methods that are in accordance with the principles of constructivism. The implications of this study emphasize the importance of developing teachers' self-regulated learning (SRL) and internet self-efficacy skills through continuous training and professional development programs to improve the quality of teaching in constructivist curricula.
Penerapan Pembelajaran Learning Cycle 5E Terhadap Penguasaan Konsep Mahasiswa Pada Materi Hukum Newton
Authors: Kholil Munawar , Arahman Emy 
Published: September 2024

Tujuan dari penelitian ini adalah untuk mngetahui pengaruh pembelajaran Learning Cycle 5E terhadap penguasaan konsep fisika mahasiswa pada materi Hukum Newton. Penelitian ini merupakan penelitian kuasi eksperimen dengan desain two group pretest-posttes design. Teknik analisis data menggunakan uji independent sample t test, hasil uji independent sample t test untuk data pretest pada nilai sig (2-tailed) adalah 0,847 dan nilai ini lebih besar dari 0,05 artinyaÂ kemampuan awal penguasaan konsep kelas eksperimen dan kelas kontrol tidak berbeda signifikan secara statistik. SedangkanÂ hasil uji independent sample t test untuk data posttest nilai sig (2-tailed) adalah 0,000 dan nilai ini lebih kecil dari 0,05 artinya rata-rata kemampuan akhir penguasaan konsep kelas eksperimen (75,61)Â dan kelas kontrol (64,61)Â berbeda signifikan secara statistik dengan perbedaan rata-rata sebesar 11. hasil ini menunjukkan bahwa pembelajaranÂ learning cycle 5E dapat dianggap sebagai metode pembelajaran yang efektif untuk meningkatkan penguasaan konsep mahasiswa pada materi Hukum Newton.
Pengaruh Strategi Discovery Learning dan Gaya Kognitif terhadap Kemampuan Pemecahan Masalah dalam Pembelajaran Fisika
Authors: Sholikhan Sholikhan , Sayyadi Muhammad 
Published: September 2024

Penelitian ini bertujuan untuk mengetahui :(1)perbedaan kemampuan pemecahan masalah antara penerapan pembelajaran discoveri dengan ekspositori (2). Perbedaan kemampuan pemecahan masalah antara siswa yang mempunyai kemampuan gaya kognitif field independent dengan field dependent. (3).Pengaruh interaksi pembelajaran discoveri dan gaya kognitif terhadap kemampuan pemecahan masalah. Penelitian ini merupakan penelitian eksperimen semu yang melibatkan 120 siswa SMA, dengan rancangan percobaan analisis factor 2x2, dan rancangan penelitian pre test post test control group design. Ada 3 variable yang digunakan yaitu variable bebas strategi pembelajaran discoveri, dan variable terikat kemampuan pemecahan masalah, sedang gaya kognitif sebagai variable moderator. Data gaya kognitif diperoleh melalui angket, sedangkan data tentang kemampuan pemecahan masalah diperoleh melalui tes. Hasil penelitian menunjukan bahwa 1) ada perbedaan kemampuan pemecahan masalah, antara penerapan pembelajaran discoveri dengan ekspositori (2). Ada perbedaan kemampuan pemecahan masalah antara siswa yang mempunyai kemampuan gaya kognitif field independent dengan field dependent; 3) ada pengaruh interaksi antara pembelajaran discoveri dan gaya kognitif terhadap kemampuan pemecahan masalah
Radio‑absorbing composite materials and coatings based on aluminum and iron oxides for electromagnetic radiation shielding
Authors: Tumilovich M. V. , Peñalosa Ovalle D. I. , Boiprav O. V. 
Published: September 2024

Radio‑absorbing composite materials, coatings and shields based on aluminum and iron oxides have been developed for protection of microwave devices from electromagnetic radiation (EMR). The patterns of changes in the characteristics of EMR reflection and transmission of electromagnetic shields based on the said powder‑like oxides have been established. It has been shown that the use of these composite materials for EMR shields can reduce the EMR reflection coefficient by 2–10 dB in the frequency range of 0.7–17.0 GHz and in the microwave range, and improve the operational properties of existing electromagnetic shields for the protection of electronic devices used for processing of limited distribution information, as well as in architectural electromagnetic shielding systems.Keywords. Composite materials, electromagnetic radiation, elecomagnetic radiation shields, aluminum and iron oxides.
Characterization of Variably Protease-Sensitive Prionopathy by Capillary Electrophoresis
Authors: Myskiw Jennifer , Bailey-Elkin Ben A , Avery Kristen , Barria Marcelo A , Ritchie Diane L , Cohen Mark L , Appleby Brian S , Booth Stephanie A 
Published: September 2024

Abstract

Variably Protease Sensitive Prionopathy (VPSPr) is a rare human prion disease that, like Creutzfeldt-Jakob disease (CJD), results in the deposition of abnormally folded prion protein aggregates in the brain and ultimate fatality. Neuropathology and clinical features of VPSPr are heterogeneous. However, the key discriminating feature is the relative sensitivity of the pathological prion protein to proteinase digestion compared to that typically seen in other human prion cases. Three major fragments of 23, 17 and 7 kDa are characteristic of the disease following digestion with proteinase K. We recently reported the utility of the highly adaptive and reproducible ProteinSimple™ capillary electrophoresis (CE) system to perform protein separation of PK digested prion protein in CJD. Consequently, we explored capillary-based electrophoresis (CE) technology as a sensitive method to detect and characterize VPSPr in a cohort of 29 cases. The unique 7 kDa fragment has high intensity, particularly in cases with the codon 129 VV genotype, but can be missed by regular Western blotting due to the small size. However, this fragment is readily detected by CE in all cases. In addition, the flexibility of CE produced highly reproducible, semi-quantitative data for determining relative proteinase K sensitivity and epitope mapping of representative cases from each codon 129 genotype (VV, MV and MM).
Metabolomics Analysis Reveals Potential Biomarkers for Diffuse Axonal Injury
Authors: Chen Weiliang , Wang Guanjun , Wu Jiayi , Li Shengwen , Yao Chunyu , Su Wen , Xu Lisheng 
Published: September 2024

Abstract

Background
Metabolism is essential for life maintenance, neurological function and injury repair, yet its role in diffuse axonal injury (DAI) is not fully understood.
Methods
30 DAI patients and 34 non-DAI patients were recruited based on the classification criteria using Magnetic Resonance Imaging (MRI) within 30 days of admission in this exploratory research. Serum samples and clinical parameters were collected upon admission, with the Glasgow Outcome Scale Extended (GOSE) at 6 months post-injury used as the neurological functional outcome. The metabolome was assayed using liquid chromatography-mass spectrometry.
Results
The DAI group and non-DAI group showed significant differences in pupillary light reflex, Glasgow Coma Scale (GCS) score, and Marshall computed tomography (CT) score, as well as in the expression levels of 27 metabolites in serum. Random forest analysis indicated that Lysophosphatidylcholine (LPC) 22:3 sn-2 and carnitine C8:1 greatly contributed to distinguishing DAI patients from non-DAI patients (MeanDecreaseGini: 3.81, 5.16). The combined prediction of DAI using these two metabolites yielded an area under the curve (AUC) of 0.944, which was higher than the combination of clinical parameters.
Conclusions
The serum metabolomics revealed potential biomarkers for DAI and has significant value for exploring pathogenesis, determining early diagnosis, and improving long-term neurological function.
From intervention studies to national programs, what are the favoring and hindering factors? A scoping review
Authors: Rola Renata Cristina Ferreira , Ramirez Tatiana Rivera , Kroeger Axel 
Published: September 2024

Abstract

Background
The translation of successful health projects into public health practice is among the most relevant challenges to pursue better health results, including the outcomes established by the United Nations sustainable development goals (SDGs). Healthcare interventions proven cost-effective should be expanded into broader policies and practices. This process is called scaling-up and its success depends on several factors. To critically think about how to scale-up projects or adapt programs, it is necessary to identify potential barriers and facilitators. In this sense, this study aims to document the type of public health programs which have been scaled up, describe the favoring and hindering factors of this process, and critically analyze the findings about it.
Methods
To reach this goal, this project used the scoping review method to synthesize the knowledge of a certain theme through available publications. The databases used in this review were PubMed, Web of Science, Cochrane Library, Scopus, VHL, Scielo, and Google Scholar.
Results
Through the selection process from a total of 7,027 search hints, 30 relevant papers were included. The found factors that impacted the scaling-up process were organized based on categories of the ExpandNet/WHO framework. The results indicate that poor "user organization", "institutional environment" and "resource mobilization" were the most frequently mentioned hindering factors for scaling-up processes. Favoring factors included strong leadership, well defined roles, good coordination, positive political environment and community support and engagement.
Conclusion
Hindering and favoring factors do not exist in isolation, but are correlated, interact, enhance or hinder one another. Beyond the practical advice given in this paper, further research recommended that investigates the association between different factors.
Factors associated with male recruitment in a multi-site randomized behavioral clinical trial targeting the metabolic syndrome: analysis of screening and recruitment data from the ELM trial
Authors: Suzuki Sumihiro , Yeh Chen , Crane Melissa M. , Daniels Bryce , Lohse Barbara , Karavolos Kelly , Olinger Tami , Nicklas Jacinda , Powell Lynda H. 
Published: September 2024

Abstract

Background
Males are underrepresented in behavioral clinical trials of lifestyle change or weight loss. Little is known about factors that facilitate or deter males from participating in such trials. The aim of this exploratory study was to describe the sample of males recruited into a multi-site behavioral trial targeting lifestyle change and remission of the metabolic syndrome and to investigate factors associated with trial interest at different stages of recruitment and overall. Similar analyses were performed for female participation to investigate the uniqueness or consistency with the findings for males.
Methods
Data collected at various stages of recruitment in an ongoing multi-site behavioral clinical trial were used. A series of logistic regressions compared respondents who moved forward to the next step of the screening process versus those who did not. These analyses were stratified by sex. A chi-squared test was used to directly compare proportions of men and women who chose to advance to the next step.
Results
Males who showed interest in the trial were more likely to be self-aware of their current health risk. Comparison of males and females showed that men tended to lose interest earlier in the recruitment process (58.3% of men vs. 66.5% of women attended an in-person information session, p < 0.001), but the proportion that moved forward among those who demonstrated initial interest was similar in men and women.
Conclusion
Efforts to increase male enrollment in behavioral clinical trials will benefit from a focus on early stages of recruitment, aiming to increase potential participants’ initial levels of interest and awareness of their health risk. As men and women differ in the reasons they choose to participate in a behavioral trial, recruitment should be tailored to sex to maximize trial participation.
Trial registration
ClinicalTrials.gov number, NCT04036006, https//clinicaltrials.gov/study/NCT04036006
Genome-wide Mendelian randomization and single-cell RNA sequencing analyses identify the causal effects of glucocorticoids on inflammatory disorders of breast
Authors: Chen Shuran , Xue Lei , Li Lixiang , Yin Zhenglang , Yang Wencan 
Published: September 2024

Abstract

Background
Inflammatory disorders of breast(IDB) is a common reason for glucocorticoids(GCs) treatment in women. However, there are no studies elucidating the relationship between GCs and the risk of IDB in general population. Therefore, we employed Mendelian randomization (MR) to explore the causal associations between GCs and IDB.
Methods
A two-sample MR analysis was performed using the summary statistics sourced from the largest genome-wide association studies(GWAS) conducted in GCs, glucocorticoid receptor-related mRNAs(GRs) and IDB. Inverse-variance weighting (IVW), MR‒Egger, and weighted median (WM) were further supported by several sensitivity analyses. Metascape and Single-cell RNA sequencing(scRNA-Seq) were used to analyze the functions and distribution of GRs.
Results
We detected causal genetic associations between GCS and IDB (OR, 1.22 (95% CI, 1.019– 1.462), P = 0.021). Further WM measure (OR, 1.294 (95% CI, 1.002– 1.671), P = 0.048) also showed similar results. No causal association was found between GCs and Childbirth-Associated Breast Infections. ScRNA-Seq confirmed that GRs were expressed in almost all immune cells, but more highly expressed in macrophages. The expression quantitative trait locus (eQTL) data suggest that NR1I3 is a high-risk factor for IDB.
Conclusions
We are the first to use MR analysis to explore the causal relationships between GCs and IDB, revealing an increased risk of IDB with GCs. These may caused by the highly expressed GRs on macrophages in breast tissue.
Therapeutic and Analgesic Efficacy of Photobiomodulation Therapy (PBMT) in the Management of Trigeminal Neuralgia: A Case Report
Authors: Al-Kufi Hani M. , Alhumadi Almustafa , Ali Marwah S. , Al-Deen Dhyaa M.J. Hirz 
Published: September 2024

Abstract

Purpose: The aim of this study is to evaluate the therapeutic and analgesic effect of PBMT in management of trigeminal neuralgia.
Methods: A 42-year-old female patient was chosen for this study. She experienced severe, unilateral, electrical-like pain episodes originating from specific points on the right side of her face, including the zygomatic region, infraorbital area, lateral side of the nose, and the upper right portion of the upper lip. The pain episodes were typically triggered by specific activities, such as speaking or washing her face. The procedure utilized photobiomodulation therapy with an EPIC X 940 nm diode laser. The laser settings included: power density of 0.5 W/cm², continuous wave (CW) emission mode, laser beam diameter on the target area of 3 cm, spot size of 7.065 cm², and an exposure time of 30 seconds for each trigger point. Treatment sessions were conducted three times per week, with a total of 12 sessions. As for the points of application, Laser irradiation was administered to each trigger area along the course of the maxillary branch of the trigeminal nerve.
Results: The results obtained from the study show a significant reduction in VAS after 12 sessions and after a period of 6 and 12 months postoperatively following PBMT.
Conclusions: According to the results obtained from the study, PBMT was effective in reducing pain in patients with idiopathic TN and can be considered an adjunctive method to pharmacotherapy, offering more satisfactory results without adverse effects. To achieve the maximum therapeutic effect using PBMT, correct diagnosis and proper knowledge of laser-tissue interaction are essential.
Exon 1 Methylation Status of CDH13 is Associated with Decreased Overall Survival and Distant Metastasis in Patients with Postoperative Colorectal Cancer
Authors: Xiang PengCheng , Li PengJu , Yuan Xiaoqi , Zhao Xiuhao , Xiao Zitian , Chen Bingguan , Biskup Ewelina , Han Junyi 
Published: September 2024

Abstract

Background
Cadherin 13 (CDH13) is a member of the cadherin superfamily that exerts tumor-suppressive effects on cancers derived from epithelial cells. Although hypermethylation of CDH13 promoter has been reported in various cancers, its prognostic value for colorectal cancer (CRC) is still controversial. The methylation alterations of CDH13 within exon 1 have not yet been investigated.
Methods
A total of 49 CRC patients were recruited for the prospective study. The methylation status of CpG sites was quantified by Bisulfite Amplicon Sequencing (BSAS) in malignant tissues and adjacent non-malignant tissues. The primary endpoint of the study was overall survival (OS) after surgery. The relationship between methylation level with pathological stage and OS was also evaluated.
Results
Compared with adjacent tissues, the overall average methylation level within exon 1 was significantly increased in tumor tissues (p < 0.001). The association study showed that the hypermethylation status of the CpG1 site was non-significantly associated with the presence of distant metastasis (p = 0.032). Moreover, the hypermethylation of two CpG sites, including CpG1 (p = 0.003) and CpG5 (p = 0.032), was associated with worse OS in CRC. Co-hypermethylation of CpG1 and CpG5 sites was significantly associated with a worse clinical outcome (HR: 4.43 [95% CI:1.27–15.46]; p = 0.019) in multivariate Cox regression analysis.
Conclusion
The methylation level of CDH13 exon 1 in CRC tissue was significantly higher than in adjacent non-malignant tissues. Hypermethylation at the CpG1 site suggests a risk of distant metastasis in CRC. The hypermethylation of the CpG1 site and CpG5 site, including the co-hypermethylation of these two sites, may serve as a valuable prognostic biomarker.