bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treestrand-Related Injuries Outnumber Projectile-Related Injuries in Arkansas Hunters, 1993–2022
Authors: Haselow Dirk Thomas 
Published: October 2024

Introduction Epidemiologic data on hunting-related injuries is sparse. Most published studies in this arena come from case reports or case series from a trauma department or state trauma registry. Relatively few of the studies have attempted to calculate rates of injury by demographic characteristics or hunting-related activities. In this study, we summarize the epidemiologic trends in hunting-related injuries in Arkansas over the last 30 years. Methods A descriptive analysis of hunter injury data collected by the Arkansas Game and Fish Commission from 1993 to 2022 was performed. Results Analyses showed that the overall number of hunting-related injuries decreased by 0.16 per 100,000 licensees per year during the study period ( P=0.0009). Projectile-related injuries decreased by 0.24 per 100,000 licensees ( P=0.00001), and treestand-related injuries increased by 0.06 per 100,000 licensees ( P=0.02) during the same time (both trends P<0.00001). treestand-related injuries now account for two thirds of all hunting-related injuries reported to the Arkansas Game and Fish Commission. Among hunters subject to hunter education certification mandates, compliance was 48.7%. Conclusions Although projectile-related hunting injuries have decreased in Arkansas in the last 30 years, treestand-related hunting injuries have increased. These injuries are largely preventable if the hunter follows treestand safety recommendations (such as using a body harness and tether at all times when off the ground), as recommended by the Treestand Manufacturers of America. In addition, implementing strategies to improve compliance with hunter education certification also may help reduce injury rates.
An Effective Computational Method for Predicting Self-Interacting Proteins Based on VGGNet Convolutional Neural Network and Gray-Level Co-occurrence Matrix
Authors: Chu Dan-Hua , An Ji-Yong , Nie Xiao-Mei 
Published: October 2024

Introduction: Predicting Self-interacting proteins (SIPs) is a crucial area of research in predicting protein functions, as well as in understanding gene-disease and disease-drug associations. These interactions are integral to numerous cellular processes and play pivotal roles within cells. However, traditional methods for identifying SIPs through biological experiments are often expensive, time-consuming, and have long cycles. Therefore, the development of effective computational methods for accurately predicting SIPs is not only necessary but also presents a significant challenge. Results: In this research, we introduce a novel computational prediction technique, VGGNGLCM, which leverages protein sequence data. This method integrates the VGGNet deep convolutional neural network (VGGN) with the Gray-Level Co-occurrence Matrix (GLCM) to detect Self-interacting proteins associations. Specifically, we initially utilized Position Specific Scoring Matrix (PSSM) to capture protein evolutionary information and integrated key features from PSSM using GLCM. We then employed VGGNet as a predictive classifier, leveraging its capabilities for powerful learning and classification prediction. Subsequently, the extracted features were input into the VGGNet deep convolutional neural network to identify Self-interacting proteins. To evaluate the performance of the VGGNGLCM model, we conducted experiments using yeast and human datasets, achieving average accuracies of 95.68% and 97.72% respectively. Additionally, we compared the prediction performance of the VGGNet classifier with that of the Convolutional Neural Network (CNN) and the state-of-the-art Support Vector Machine (SVM) using the same feature extraction method. We also compared the prediction ability of VGGNGLCM with other existing approaches. The comparison results further demonstrate the superior performance of VGGNGLCM over other prediction models in this domain. Conclusion: The experimental verification further strengthens the evidence that VGGNGLCM is effective and robust compared to existing methods. It also highlights the high accuracy and robustness of the VGGNGLCM model in predicting Self-interacting proteins (SIPs). Consequently, we believe that the VGGNGLCM method serves as a valuable computational tool and can catalyze extensive bioinformatics research related to SIPs prediction.
Long Lasting Insecticide-Treated Nets Utilization and Associated Factors Among Pregnant Women in Shebel Berenta District, Northwest Ethiopia
Authors: Getnet Yeshitla , Teym Abraham , Wubie Moges , Shiferaw Sintayehu , Tilahun Assaye Bayou , Aneley Zelalem , Mekonen Abera Habitamu , Temesgen Habtamu 
Published: October 2024

Background: Insecticide-treated bed nets are cost-effective vector control methods for malaria prevention. Malaria during pregnancy poses a significant health problem in Ethiopia. This study aimed to assess insecticide-treated nets utilization and associated factors among pregnant women in Shebel Berenta District, Northwest Ethiopia. Objective: To assess insecticide-treated bed nets utilization and associated factors among pregnant women in Shebel Berenta District, Northwest Ethiopia, in 2023. Methods: A community-based cross-sectional study was conducted from March 15 to April 30, 2023, on 505 randomly selected pregnant women. Data were collected using a pre-tested structured questionnaire and observational checklist, analyzed with EpiData 3.1 and SPSS 25. Significant factors associated with long-lasting insecticide-treated nets were identified (P < .05, 95% CI) and were reported as statistically significant factors associated with the utilization of insecticide-treated bed nets. Results: The utilization of long-lasting insecticide-treated nets was 45.10% [95% CI: 40.5%-49.2%]. Mothers who had antenatal care follow-up (AOR = 3.359; 95%CI: 1.829, 6.166), mothers with illiterate educational status (AOR = 0.196; 95%CI: 0.064-0.603), and mothers who had received information (message) (AOR = 8.102; 95%CI: 3.942-16.653) were significantly associated with long lasting insecticide-treated net utilization. Conclusion: Utilization of long lasting insecticide-treated nets by pregnant women was 45.1%, which was lower than the WHO standard. Attending antenatal care, receiving information (messages) about malaria and long lasting insecticide-treated net, and mother’s being literate had a substantial impact on long lasting insecticide-treated net utilization. Therefore, efforts should be made to strengthen ANC service, health information and women’s educational status to increase utilization of long lasting insecticide-treated nets.
Magnetic Resonance Imaging – Derived Psoas Muscle Area and Survival in Patients Treated Invasively for Peripheral Arterial Disease
Authors: Söderlund Minea , Huhtamo Henni , Protto Sara , Hernesniemi Jussi A. , Vakhitov Damir , Oksala Niku , Khan Niina 
Published: October 2024

Background and Aims: Psoas muscle parameters estimated from computed tomography images, as surrogates for sarcopenia, have been found to be associated with post-interventional outcomes after a wide range of cardiovascular procedures. The pre-interventional assessment in patients undergoing invasive treatment for peripheral arterial disease is increasingly often carried out with magnetic resonance imaging (MRI), and we therefore sought to investigate the predictive potential of MRI-derived psoas muscle area in this cohort. Methods: A total of 899 patients with available sufficient quality pre-interventional MRI conducted within 6 months prior to treatment undergoing open, endovascular, or hybrid revascularization procedures for claudication and/or limb-threatening ischemia at Tampere University hospital between 2010 and 2020 were retrospectively studied in this single-center cohort study. The follow-up lasted until 17 June 2021. Psoas muscle areas were measured from the magnetic resonance images at the L4 level, and the reliability of muscle parameter measurements was tested with intraclass correlation coefficient analysis. The average psoas muscle area values (mean of left and right psoas surface areas) were z-scored and analyzed separately for men and women. Results: The median follow-up time was 5.9 years (interquartile range (IQR) = 2.7–7.8), and the overall mortality count was 259 (28.8%) (29.5% n = 168/569 for men and 27.6% n = 91/330 for women). The intraclass correlation coefficient analysis showed excellent interrater reliability for psoas muscle measurements. The muscle surface areas were larger in men (mean = 7.58 cm2) compared to women (mean = 5.27 cm2) (p < 0.001). Higher psoas muscle area was associated with better survival in women (p = 0.003, hazard ratio (HR) = 0.71, 95% confidence interval (CI) = 0.6–0.9 per 1 SD), whereas in men, an independent association of the muscle parameter with mortality was not found. Conclusions: MRI-derived psoas muscle area may be a prognostic factor for clinical use.
Preoperative Depression is Associated With a Higher Risk of Bleeding in Type a Aortic Dissection Repair: A Population Study of National Inpatient Sample From 2015-2020
Authors: Li Renxi , Luo Qianyun , Huddleston Stephen J. 
Published: October 2024

Background Depression is highly prevalent in patients with aortic diseases. While depression has been shown to predispose patients to adverse outcomes after surgery, its impact on postoperative outcomes in Stanford Type A Aortic Dissection (TAAD) has not been established. This study aimed to conduct a population-based examination of the effect of preoperative depression on in-hospital outcomes after TAAD using the National/Nationwide Inpatient Sample (NIS) database, the largest all-layer database in the US. Methods Patients undergoing TAAD repair were identified in NIS from the last quarter of 2015-2020. Multivariable logistic regressions were used to compare in-hospital outcomes between patients with and without preoperative depression, adjusted for demographics, comorbidities, hospital characteristics, primary payer status, and transfer status. Results There were 321 (7.50%) patients with depression and 3961 (92.50%) non-depressive patients who underwent TAAD repair. Patients with and without depression had comparable in-hospital mortality (11.84% vs 15.37%, P = 0.35). However, Patients with depression had a higher risk of hemorrhage/hematoma (83.49% vs 76.6%, aOR 1.593, 95 CI 1.161-2.184, P < 0.01) and a higher rate of transfer out (40.81% vs 32.62%, aOR 1.396, 95 CI 1.077-1.81, P = 0.01). All other in-hospital complications, hospital length of stay (LOS), and total hospital charge were comparable between patients with and without depression. Conclusion Preoperative depression is associated with a higher risk of bleeding after TAAD repair. This may be due to anti-depression treatment, such as Selective Serotonin Reuptake Inhibitors (SSRIs), that can disrupt platelet function and lead to abnormal bleeding. While depression is not associated with other major outcomes, preoperative depression screening, as well as hemostatic monitoring and appropriate blood management in patients with depression may be crucial in preventing bleeding complications in TAAD repair.
Possible clinical and radiological predictors of haemorrhagic transformation in acute stroke patients undergoing dual antiplatelet therapy: a clinical study
Authors: Bagnato Maria Rosaria , Maestrini Ilaria , Bruno Leonardo , Ciullo Ilaria , D’Agostino Federica , Lacidogna Giordano , Marrama Federico , Mascolo Alfredo Paolo , Rocco Alessandro , Diomedi Marina 
Published: October 2024

Background: The predictors of intracranial haemorrhagic transformation (HT) in acute ischaemic stroke (AIS) patients undergoing dual antiplatelet therapy (DAPT) are not well known. Objectives: The aim of this study is to identify the possible clinical and radiological predictors of HT in patients, irrespective of clinical indication for this treatment. Design: This study is a monocentric cohort retrospective study. Methods: We enrolled consecutive AIS patients, from our prospective register, admitted to Stroke Unit between June 2021 and June 2023 undergoing DAPT with Acetylsalicylic Acid and Clopidogrel within 72 h from symptoms onset. According to current guidelines, DAPT indication was for patients with a minor stroke, symptomatic intracranial artery stenosis and carotid angioplasty stenting. We collected clinical, demographical and radiological data. We used ABC/2 method to measure stroke volume in magnetic resonance imaging (MRI)/Diffusion-weighted imaging (DWI) sequences performed within 48 h. The primary outcome was the presence of HT at non-contrast brain computed tomography, performed 7 days after commencing DAPT. Results: One hundred ninety-four patients were included. Twenty-eight (14.4%) presented HT. Higher NIH Stroke Scale (NIHSS) and MRI/DWI lesion volume related to increased risk of HT ( p < 0.001). Reperfusion therapy and mechanical thrombectomy (MT), stent placement and a loading dose (LD) of dual antiplatelet or Clopidogrel were associated with a higher occurrence of HT ( p < 0.05). Furthermore, we individuated an NIHSS cut-off value >4 (area under the curve (AUC) 0.80, sensitivity 0.82, specificity 0.65) and a volume cut-off value >8.2 ml (AUC 0.82, sensitivity 0.79, specificity 0.80) associated with an increased risk of HT (respectively, adjusted odds ratio (adj. OR) 6.5, confidence interval (CI) 1.3–32.7, p = 0.024 and adj. OR 11.0, CI 3.1–39.2, p < 0.001). Conclusion: In clinical practice, MT treatment, antiplatelet LD administration, stent placement and clinical severity may relate to a higher risk of HT in patients with AIS and DAPT in the acute phase. In particular, we found that lesion volume cut-off could help to identify patients at greater risk of HT, regardless of the indication for DAPT.
Core psychosocial insights, challenges, and opportunities in the orthopedic surgery care of children and adolescents
Authors: Hamilton Amber A , Wongcharoenwatana Jidapa , Hoellwarth Jason S , Geffner Adam , Mehta Rena , Epstein B Sue , Fabricant Peter D , Fragomen Austin T , Rozbruch S Robert 
Published: October 2024

Purpose: This is the second phase in an investigation of the psychosocial impact of orthopedic surgery on adolescents. What are the core psychosocial factors that shape the experience of adolescent patients aged 11–18 who are undergoing orthopedic surgery? Methods: Two 43-question surveys (preoperative and postoperative) were developed as modified versions of the survey used in phase 1. The preoperative survey was administered 2 weeks before surgery. The postoperative survey was administered 6 weeks later. Responses were collected from free-response and Likert-scale questions exploring patient–physician relationships, office visits/hospital stays, family, peers, academics, sports, and surgical expectations. The survey was administered prospectively to patients aged 11–18 undergoing limb lengthening/reconstruction, pediatric, spine, sports, or hand/upper extremity orthopedic surgery. In all, 135 patients were identified; 105 were enrolled and completed both surveys. Results: There were some statistically significant changes in responses to questions regarding office visits/hospital stays, patient–physician relationships, friends/community, academic performance, and expectations for surgical experience throughout the perioperative period. There were no statistically significant changes in responses to questions regarding the role of parent/family and sports. There was no statistically significant difference between the female and male genders or between age groups in any of the domains. Overall statistical significance in this study did not consistently correlate to clinical significance. Conclusion: Adolescents require psychosocial support from their surgeons, caregivers, and peers in addition to respect for their independence and personal needs. Level of evidence: Level II.
Trends in food and nutrition literacy in obesity: A bibliometric analysis
Authors: Madali-Kafes Berna , Kafes Mustafa 
Published: October 2024

Background Low food and nutrition literacy is a significant factor in obesity prevalence, adversely impacting economic and individual health outcomes, with limited research impeding effective public health interventions. Objectives This study seeks to provide a comprehensive overview of scientific research conducted over the past three decades on food and nutrition literacy in relation to obesity. The objective is to evaluate the thematic focus of studies in this domain. Methods A bibliometric analysis methodology, known as a quantitative technique, was employed to investigate scientific studies published in the Web of Science database between 1995 and 2023. The analysis, conducted using the Bibliometrix library in R StudioIDE, considers key variables such as publication year, authorship, countries of origin, high-impact journals, citations, collaborations, and keywords. Results The research encompasses 755 articles, revealing a notable surge in publications post-2007. Remarkably, studies predominantly concentrate on the food and nutrition literacy of children and adolescents. The most cited author is Velardo, whose 2015 article focuses on defining nutritional literacy. The total number of publications from the 10 countries with the most productive authors in this field is 590, accounting for 78.15% of the dataset. The integration of digital media tools among this demographic has sparked innovative research trends. Conclusions Analysis of the data underscores a shortage of research in the literature, emphasizing the need for future studies to prioritize investigating the connection between food and nutrition literacy and obesity in children and adolescents. Bridging this knowledge gap is imperative for developing effective strategies to address and mitigate the obesity epidemic in these specific age groups.
Motivated information avoidance in an mHealth weight loss intervention: Associations between unmet behavioral goals and likelihood of viewing program messages
Authors: Hurley Lex , Nezami Brooke T , Valle Carmina G , Tate Deborah F 
Published: October 2024

Background Program engagement is positively associated with improved outcomes in mobile health (mHealth) interventions, but little is known about which factors may increase or decrease the likelihood of participants viewing program messages. This study examined the association between daily behavioral goal achievement and likelihood of reading daily messages, and if this relationship is moderated by baseline depressive symptoms in an mHealth weight loss intervention. Methods Data come from a 12-week microrandomized pilot mHealth weight management trial that tested the effects of daily messages on behavioral goals among 52 young adults (78.8% female, 61.5% white, ages 21–35). Conditional growth curve modeling was used to regress message viewing indicators onto the number of daily behavioral goals that participants had not met at the time of message receipt, with testing for moderation by depressive symptoms and controlling for covariates clustered within participants over time. Results For each additional goal not met at the time of message receipt, participants were 34.8% less likely to read any message sent ( p < 0.0001), and this relationship did not appear to be related to depressive symptoms ( p = 0.1). Conclusions Participants may tend to avoid reading program messages when they know they are not meeting goals in a program, possibly due to motivated information avoidance to prevent negative emotional reactions from anticipated negative feedback messages. Future interventions may want to consider ways to contact participants who may be struggling in programs and also avoiding viewing standard message pushes in order to reduce the risk of disengagement.
Association of hs-CRP with Serum Creatinine Levels in Chronic Kidney Diseases
Authors: Goriya Shivani , Priya Nivedita 
Published: October 2024

Introduction Chronic kidney disease (CKD) is a prevalent condition characterized by a progressive decline in kidney function over time. It is associated with various complications, including cardiovascular disease and mortality. Inflammation, as indicated by elevated levels of high-sensitivity C-reactive protein (hs-CRP), has been implicated in the pathogenesis and progression of CKD. Serum creatinine (S. creatinine) levels, on the other hand, are commonly used as a marker to estimate kidney function. Aim The objective of this study was to examine the relationship between hs-CRP levels and S. creatinine levels in CKD patients. By investigating this association, this study aimed to shed light on the potential interplay between inflammation and kidney dysfunction in CKD. Methods We conducted a cross-sectional study in the Parul Sevashram Hospital, Vadodara. The study consisted of 80 CKD patients with 51 males and 29 females. The hs-CRP and creatinine levels were estimated for the study and further evaluated statistically for finding the association between them. Results The study observed a gender distribution with 63.75% male and 36.25% female patients. Among males, 41.17% had hs-CRP levels >2 mg/L, with a mean ± standard deviation (SD) creatinine value of 4.63 ± 0.32 mg/dL. In females, only 13.79% had hs-CRP levels >2 mg/L, with a mean ± SD creatinine value of 4.62 ± 0.30 mg/dL. The statistical analysis using Fisher’s exact test showed a highly significant association between hs-CRP and S. creatinine levels ( P < .01). Conclusion This study demonstrated a strong association between hs-CRP levels and S. creatinine levels in patients with CKD. As S. creatinine levels increased, there was a corresponding rise in hs-CRP levels. This suggests that monitoring hs-CRP levels could be valuable in assessing the progression of renal dysfunction and predicting cardiovascular complications in CKD patients. Further research is needed to fully comprehend the underlying mechanisms driving this association.