bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consensus Gene Expression Subtypes Of Epithelial Tumors
Authors: Sadanandam Anguraj 
Published: March 2016

AbstractWhile the heterogeneity of cancer is increasingly appreciated, it is also clear that recurrently deregulated pathways are shared between tumors across tissue types. To identify similarities in subsets of tumors from multiple epithelial organs, we performed transcriptome profile analysis of different epithelial tumors and cell lines (n=2928) from 17 different organs. We identified three to seven consensus gene expression subtypes in epithelial tumors and cell lines, irrespective of the organ-specific origin. These consensus subtypes showed biological significance. Moreover, we identified specific gene signatures that could be used to develop clinical assays for future application of this classification system. Overall, our study identifies consensus transcriptome subtypes across organ-specific tumors and highlights new avenues for precision therapy irrespective of the organ of origin.
Impact of soil and air contaminants on the composition of rail-head surface rust
Authors: El-Hashemy Mohammed Abd El-Samea , Nazeer Ahmed Abdel 
Published: March 2016

Purpose
– The purpose of this paper is to explore the environment around the rail track at different sites in Nile Delta region, Egypt, through the measurements of the air pollutants and corrosive ionic species present in surface soil and also to investigate the impact of the existing contaminants on the composition of iron rust formed on the rail head surface at these sites and then the durability of rail itself.

Design/methodology/approach
– The soil characterization was studied by means of sieve shakers, pH meter, conductivity meter and ion chromatography instrument. Scanning electron microscopy, energy dispersive spectrometry, Fourier transform infrared spectroscopy and X-ray diffraction were used to characterize the rust layer formed on the rail head surface.

Findings
– The results showed the relation between the contaminants and the composition of the rust layer. Magnetite and goethite were the major phases identified in the rust layers. Akaganeite was detected in the marine atmosphere. Iron sulfide and iron oxide nitrate hydroxide were detected in environments rich in H2S and NO2 gases, respectively. The appearance of phases like FeCl2 and FeOCl only at marine atmospheres reflects that the corrosive species in suspended particulate matter like chloride ion have a higher effect on the rust composition of the rail head surface than that in surface soil layer.

Originality/value
– This paper revealed the impact of air and soil contaminants on the composition of rust layer on the rail head surface and may provide guidance for the durability of rails and the necessity for their preservation.
Self-limiting film formation mechanism of zirconium based conversion coating on mild steel
Authors: Ghanbari Alireza , Attar Mohammadreza Mohammadzade 
Published: March 2016

Purpose
– The purpose of this paper is to investigate the film formation mechanism of zirconium-based conversion layer on mild steel. In this way, different approaches were used to show the self-limiting film formation mechanism.

Design/methodology/approach
– To determine this mechanism, film formation was detected using DC polarization, spectrophotometric technique and surface analysis techniques, including field emission scanning electron microscope (FE-SEM) and atomic force microscopy (AFM).

Findings
– DC polarization resistance of surface increased with increasing of mild steel immersion time in the conversion coating bath, reaching to a plateau region. On the other hand, zirconium ion concentration decreased during the beginning of the film formation process and continued with a constant concentration, showing the expiry of the process after some minutes.

Originality/value
– This paper deals with the film formation mechanism of the zirconium-based conversion layer that includes valuable findings to monitor the process.
What firm characteristics determine women ' s employment in manufacturing? Evidence from Bangladesh
Authors: Ahmed Salma , Feeny Simon , Posso Alberto 
Published: March 2016

Purpose– The purpose of this paper is to investigate the principal determinants of women’s employment in the manufacturing sector of Bangladesh using a firm-level panel data from the World Bank’s “Enterprise Survey” for the years 2007, 2011 and 2013. The paper sheds light on the demand-side factors, mainly firm-level characteristics, which also influence this decision.Design/methodology/approach– The authors estimate a fractional logit model to model a dependent variable that is limited by zero from below and one from above.Findings– The results indicate that firm size, whether medium or large, and firms’ export-oriented activities, have an important impact on women’s employment in the manufacturing sector in Bangladesh. Moreover, the authors find that women are significantly more likely to work in unskilled-labour-intensive industries within the manufacturing sector.Research limitations/implications– The research is limited to Bangladesh; however, much of the evidence presented here has implications that are relevant to policymakers in other developing countries.Practical implications– The study identifies factors that affect female employment, that is, where the main constraints to increase female labour force participation. The study focuses on the demand-side factors, which has been somewhat neglected in recent years. As such, it has practical policy implications.Social implications– Focusing on female employment in Bangladesh also sheds light on the nexus between labour market opportunities and social change within a country that is characterised by extreme patriarchy, which has wide-reaching implications.Originality/value– This is an original and comprehensive paper by the authors.
Regulating internet access in UK public libraries: legal compliance and ethical dilemmas
Authors: Muir Adrienne , Spacey Rachel , Cooke Louise , Creaser Claire 
Published: March 2016

Purpose– This paper aims to consider selected results from the Arts and Humanities Research Council (AHRC)-funded “Managing Access to the internet in Public Libraries” (MAIPLE) project, from 2012-2014. MAIPLE has explored the ways in which public library services manage use of the internet connections that they provide for the public. This included the how public library services balance their legal obligations and the needs of their communities in a public space and the ethical dilemmas that arise.Design/methodology/approach– The researchers used a mixed-method approach involving a review of the literature, legal analysis, a questionnaire survey and case studies in five public library authorities.Findings– UK public library services use a range of methods to regulate internet access. The research also confirms previous findings that filtering software is an ubiquitous tool for controlling access to and protecting library users from “inappropriate”, illegal and harmful internet content. There is a general, if sometimes reluctant, acceptance of filtering software as a practical tool by library staff, which seems to contrast with professional codes of ethics and attitudes in other countries. The research indicates that public library internet access will be a valued service for some time to come, but that some aspects of how public library services regulate internet access is currently managed can have socially undesirable consequences, including blocking legitimate sites and preventing users from accessing government services. Education could play a greater part in helping the general population to exercise judgement in selection of materials to view and use. This does not preclude implementing stricter controls to protect children, whilst allowing public libraries to continue providing a social good to those who are unable to otherwise participate in the digital age.Research limitations/implications– The response to the survey was 39 per cent meaning that findings may not apply across the whole of the UK. The findings of this study are compared with and supplemented by other quantitative sources, but a strength of this study is the depth of understanding afforded by the use of case studies.Originality/value– This paper provides both a quantitative and qualitative analysis of how internet access is managed in UK public libraries, including how library services fulfil their legal obligations and the ethical implications of how they balance their role in facilitating access to information with their perceived role as a safe and trusted environment for all members of their communities. The findings add to the international discussion on this issue and stimulate debate and policy making in the UK.
Response to Mirjam J. Curno
Authors: Hauptman Robert 
Published: March 2016

Purpose
– This paper aims to reflect on the area of publication ethics as related to scholarship responding to Curno’s invited paper, “Challenges to ethical publishing in the digital era”.

Design/methodology/approach
– This viewpoint draws up the rich experience of the author over an extended academic career. The constructed view blends empiricism and literary sources to develop justified position.

Findings
– There is resonance with Curno’s view. However, a counter position regarding the effect of the Internet on plagiarism is offered. Opinion is given which extends across disciplines rather than remaining in the confines of science and technology.

Originality/value
– The response to Curno’s paper provides some alternative views and suggests directions in which the landscape of concern might be extended.
A community arts programme for older people: an evaluation
Authors: Stickley Theodore , Hui Ada , Souter Gary , Mills Danielle 
Published: March 2016

Purpose
– The purpose of this paper is to present an evaluation of a community-based arts programme for older people in Nottinghamshire.

Design/methodology/approach
– The evaluation was conducted using a combination of pre- and post-initiative quantitative questionnaires and qualitative focus group interviews. This paper focuses upon the findings from the focus groups.

Findings
– Participants reported feeling more positively about ageing and being more motivated to pursue new opportunities at the end of the programme. Five themes emerged from the focus group interviews, namely age and ageing, the finished product, new opportunities, aspirations and the future and personal benefits. These related to increased confidence, having greater creative expression, meaningful occupation and opportunities for socialisation.

Social implications
– The programme was found to be successful in helping individuals feel more positive about their age, to feel more confident and motivated, to engage with others through mutual creativity, as well as to challenge negative social stereotypes of older people.

Originality/value
– The paper will be of relevance and value to those working with older people and those with an interest in the arts. This evaluation demonstrates the diversity of the older population with older citizen’s voices being at the heart of the programme.
Do computers increase older people’s inclusion and wellbeing?
Authors: Holttum Sue 
Published: March 2016

Purpose
– The purpose of this paper is to consider two recent studies on computer use by older people, who may become increasingly isolated due to infirmity and sensory impairments. Older people are less likely to use computer technology yet it has been suggested that it may help reduce isolation. These studies inquired into older people’s experience with computers.

Design/methodology/approach
– The first paper discussed here explored how a sample of older people in the USA acquired a computer and whether it contributed to their well-being. The second paper was about a similar study with a sample of older people in the UK.

Findings
– In the US sample, people who saw tablet computers being used by a friend were likely to purchase one. In the UK sample, people seemed to have had to overcome more fears of using computer technology, but in both samples, once initial difficulties were overcome, people were enthusiastic about using them. In both, people felt more able to keep up hobbies and interests through finding information or connecting with interest groups online, and able to keep connected with family members.

Originality/value
– In light of increasing migration of services and information to the internet, these studies explored the things that help and hinder older people in terms of using computers, in order to address the digital divide, whereby those unable to use them can be left isolated and with reduced information and support. These studies were able to explore personal meanings of computer use and specific fears and difficulties, which are important to understand in planning for training and support for older people who are not yet on line. They also demonstrated that, alongside face-to-face interaction, being online was experienced as reducing people’s isolation and enhancing their lives.
Stabilization of silica-coated silver iodide nanoparticles by ethanol-washing
Authors: Kobayashi Yoshio , Ayame Tetsuya , Shibuya Kyosuke , Nakagawa Tomohiko , Kubota Yohsuke , Gonda Kohsuke , Ohuchi Noriaki 
Published: March 2016

Purpose
– This paper aims to propose a simple method for stabilizing silica-coated silver iodide (AgI/SiO2) core-shell particles, of which a colloid solution functions as an X-ray contrast agent.

Design/methodology/approach
– A colloid solution of AgI nanoparticles was prepared by mixing silver perchlorate and potassium iodide in water. The AgI/SiO2 nanoparticles were fabricated by a sol-gel method using NaOH, H2O and tetraethylorthosilicate in ethanol in the presence of AgI nanoparticles surface-modified with 3-mercaptopropyltrimethoxysilane.

Findings
– The silica shells of AgI/SiO2 particles were dissolved near the AgI nanoparticle surface, when they were washed by a process composed of centrifugation, removal of supernatant with decantation, addition of water as a washing solution and a shake with a vortex mixer. In contrast, the shells were not damaged by using ethanol as the washing solution, i.e. ethanol-washing. An X-ray photoelectron spectroscopy spectrum of the silica was changed after the ethanol-washing, which indicated that the ethanol-washing had an effect on the chemical bonds in silica. The effect also acted on the silica shells of AgI/SiO2 particles, which did not damage the core-shell structure, i.e. controlled the dissolution of shell.

Originality/value
– The paper demonstrates that the ethanol-washing is quite useful for stabilizing the core-shell structure composed of the silica shells.
Social impact measurement: why do stakeholders matter?
Authors: Costa Ericka , Pesci Caterina 
Published: March 2016

Purpose– This paper aims to discuss the notion of social impact of social impact measurement in social enterprises by supporting the multiple-constituency theory as a contribution to this under-theorised issue. Moreover, the paper proposes the stakeholder-based approach as the most appropriate solution for selection among metrics related to the growing number of social impact measurements.Design/methodology/approach– The paper proposes a review of social impact measurement studies by considering contributions from both academia and practitioners, while providing a reassessment and conceptualisation of this issue in terms of the multiple-constituency theory.Findings– The paper criticises the “golden standard approach” to social impact measurement according to which social enterprises have to find one standardised metric capable of determining an organisation’s real impact. The golden standard approach promotes a more “political view” of social enterprises, according to which multiple stakeholders set performance standards based on their viewpoints regarding the measurement’s purposes.Research limitations/implications– The paper responds to the urgent call to define a theoretical framework that might guide social impact measurement, seeking to avoid the current lack of order and transparency in existing practices that could serve as a vehicle for camouflaging corporate social un-sustainability.Originality/value– The multiple-constituency approach should discourage organisations from opportunistically selecting a social impact measurement with the sole purpose of proving a higher impact, as, within the proposed new perspective, social impact metrics are no longer managed independently by the social enterprises themselves. Instead, these metrics are defined and constructed with the stakeholders. As a result, social enterprises’ manipulative intentions should diminish.
Draft Genome Sequence of
Psychrobacter piscatorii
Strain LQ58, a Psychrotolerant Bacterium Isolated from a Deep-Sea Hydrothermal Vent
Authors: Zhou Meixian , Dong Binbin , Liu Qing 
Published: March 2016

ABSTRACT

Here, we report the 3.1-Mb draft genome sequence of
Psychrobacter piscatorii
strain LQ58, isolated from a deep-sea hydrothermal vent on the East Pacific Rise. The sequence will provide further insight into the environmental adaptation of psychrotolerant bacteria and the development of novel cold-active enzymes for industrial application.
Draft Genome Sequence of the Butyric Acid Producer
Clostridium tyrobutyricum
Strain CIP I-776 (IFP923)
Authors: Wasels François , Clément Benjamin , Lopes Ferreira Nicolas 
Published: March 2016

ABSTRACT

Here, we report the draft genome sequence of
Clostridium tyrobutyricum
CIP I-776 (IFP923), an efficient producer of butyric acid. The genome consists of a single chromosome of 3.19 Mb and provides useful data concerning the metabolic capacities of the strain.
Draft Genome Sequence of
Lactobacillus casei
DPC6800, an Isolate with the Potential to Diversify Flavor in Cheese
Authors: Stefanovic Ewelina , Casey Aidan , Cotter Paul , Cavanagh Daniel , Fitzgerald Gerald , McAuliffe Olivia 
Published: March 2016

ABSTRACT

Lactobacillus casei
is a nonstarter lactic acid bacterium commonly present in various types of cheeses. It is believed that strains of this species have a significant impact on the development of cheese flavor. The draft genome sequence of
L. casei
DPC6800, isolated from a semi-hard Dutch cheese, is reported.
Draft Genome Sequence of
Alcaligenes faecalis
Strain IITR89, an Indole-Oxidizing Bacterium
Authors: Regar Raj Kumar , Gaur Vivek Kumar , Mishra Gayatri , Jadhao Sudhir , Kamthan Mohan , Manickam Natesan 
Published: March 2016

ABSTRACT

We report the draft genome sequence of
Alcaligenes faecalis
strain IITR89, a bacterium able to form indigo by utilizing indole as the sole carbon source. The
Alcaligenes
species is increasingly reported for biodegradation of diverse toxicants and thus complete sequencing may provide insight into biodegradation capabilities and other phenotypes.
Genome Sequence of a Virulent
Pseudomonas aeruginosa
Strain, 12-4-4(59), Isolated from the Blood Culture of a Burn Patient
Authors: Karna S. L. Rajasekhar , Chen Tsute , Chen Ping , Peacock Trent J. , Abercrombie Johnathan J. , Leung Kai P. 
Published: March 2016

ABSTRACT

Pseudomonas aeruginosa
is an opportunistic pathogen that frequently infects wounds, significantly impairs wound healing, and causes morbidity and mortality in burn patients. Here, we report the genome sequence of a virulent strain of
P. aeruginosa
, 12-4-4(59), isolated from the blood culture of a burn patient.
Complete Genome Sequence of PM105, a New
Pseudomonas aeruginosa
B3-Like Transposable Phage
Authors: Pourcel Christine , Midoux Cédric , Bourkaltseva Maria , Pleteneva Elena , Krylov Victor 
Published: March 2016

ABSTRACT

The complete genome of the
Pseudomonas aeruginosa
bacteriophage PM105 is 39,593 bp long. The phage belongs to the B3 family of transposable Mu-like phages, as confirmed by the presence of bacterial DNA joined to the phage genome ends. PM105, together with other B3-like phages, form a newly arising species.
Draft Genome of
Rhodococcus rhodochrous
TRN7, Isolated from the Coast of Trindade Island, Brazil
Authors: Rodrigues Edmo M. , Pylro Victor S. , Dobbler Priscila T. , Victoria Filipe , Roesch Luiz F. W. , Tótola Marcos R. 
Published: March 2016

ABSTRACT

Here, we present a draft genome and annotation of
Rhodococcus rhodochrous
TRN7, isolated from Trindade Island, Brazil, which will provide genetic data to benefit the understanding of its metabolism.
Draft Genome Sequence of a Chlorinated-Ethene Degrader,
Cupriavidus necator
Strain PHE3-6 (NBRC 110655)
Authors: Yonezuka Kenta , Shimodaira Jun , Tabata Michiro , Nagase Shun , Kasai Daisuke , Hosoyama Akira , Yamazoe Atsushi , Fujita Nobuyuki , Fukuda Masao 
Published: March 2016

ABSTRACT

Cupriavidus necator
strain PHE3-6 grows on phenol as a sole carbon source and cometabolizes
cis-
and
trans-
dichloroethenes and trichloroethene. Here, we report the draft genome sequence of PHE3-6, which provides insights into the degradation system of phenol and chlorinated ethenes.
Implementation of routine foot check in patients with diabetes on hemodialysis: associations with outcomes
Authors: Marn Pernat Andreja , Peršič Vanja , Usvyat Len , Saunders Lynn , Rogus John , Maddux Franklin W , Lacson Eduardo , Kotanko Peter 
Published: March 2016

ObjectivePatients with diabetes are at increased risk of foot ulcers, which may result in limb amputations. While regular foot care prevents ulcerations and amputation in those patients with diabetes not on dialysis, evidence is limited in diabetic hemodialysis patients. We investigated the association between the implementation of a routine foot check program in diabetic incident hemodialysis patients, and major lower limb amputations.MethodsIn 1/2008, monthly intradialytic foot checks were implemented as part of standard clinic care in all Fresenius Medical Care North America hemodialysis facilities. Patients with diabetes who initiated hemodialysis between 1/2004 and 12/2007 constituted the preimplementation cohort, and patients starting hemodialysis between 1/2008 and 12/2011 comprised the postimplementation cohort. In addition, we conducted a sensitivity analysis where we excluded patients from the clinics with <10 patients in the postimplementation period and where percent difference in patient with diabetes number between postimplementation and preimplementation period was <20%. We compared lower limb amputation rates employing Poisson regression models with offset of exposure time in these two cohorts.ResultsWe studied 35 513 patients in the preimplementation and 25 779 patients in the postimplementation cohort. In the postimplementation cohort, amputation rate decreased by 17% (p=0.0034). The major lower limb amputation rate was 1.30 per 100 patient years in preimplementation and 1.07 in postimplementation cohort. These beneficial results were corroborated in the multivariate analysis (p=0.0175) and were even more pronounced in the sensitivity analysis (p=0.0083).ConclusionMonthly foot checks are associated with reduction of major lower limb amputations in diabetic incident hemodialysis patients.