bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of microbial control measures on farmstead cheesemaking and antimicrobial resistance of Staphylococcus aureus and Enterococcus spp. isolates
Authors: Kang Il‐Byeong , Kim Dong‐Hyeon , Chon Jung‐Whan , Seo Kun‐Ho 
Published: December 2017

AbstractThe effect of microbial control measures in farmstead cheese making was evaluated in a small dairy farm in Gyeong‐gi province, Korea. Teat washing and pasteurization significantly (p < .05) reduced the level of indicator bacteria (mesophilic aerobes, total coliforms, and Escherichia coli). However, farmstead cheeses were contaminated with increased levels of mesophilic aerobes, total coliforms, Staphylococcus aureus, and Enterococcus faecium during post‐pasteurization steps, including the cheesemaking process and ripening. S. aureus isolates from cheese samples exhibited antibiotic resistance to penicillin/ampicillin, whereas teat and milk samples showed resistance to erythromycin/ciprofloxacin. Enterococcus spp. isolates had the highest proportion of organisms resistant to erythromycin and tetracycline among multidrug‐resistant strains. To ensure the safety of farmstead cheese, customized management systems and intervention methods should be established by focusing on control measures for not only preprocessing and pasteurization but also post‐pasteurization steps.Practical applicationsOwing to renewed interest in specialty cheeses, small‐scale farmstead cheeses are actively produced worldwide. However, because of various manufacturing steps, including milking, pasteurization, ripening, and storage, farmstead cheese could pose a high risk for the presence of foodborne pathogens. In the current study, teat washing and milk pasteurization effectively reduced microbial contamination loads. However, farmstead cheeses were contaminated post‐pasteurization with increased levels of indicator and pathogenic microorganisms. Comprehensive management systems should be implemented and should focus not only on preprocessing and pasteurization but also on post‐pasteurization steps to ensure the safety of farmstead cheese.
Links between sleep and daytime behaviour problems in children with Down syndrome
Authors: Esbensen A. J. , Hoffman E. K. , Beebe D. W. , Byars K. C. , Epstein J. 
Published: December 2017

AbstractBackgroundIn the general population, sleep problems have an impact on daytime performance. Despite sleep problems being common among children with Down syndrome, the impact of sleep problems on daytime behaviours in school‐age children with Down syndrome is an understudied topic. Our study examined the relationship between parent‐reported and actigraphy‐measured sleep duration and sleep quality with parent and teacher reports of daytime behaviour problems among school‐age children with Down syndrome.MethodThirty school‐age children with Down syndrome wore an actigraph watch for a week at home at night. Their parent completed ratings of the child's sleep during that same week. Their parent and teacher completed a battery of measures to assess daytime behaviour.ResultsParent reports of restless sleep behaviours on the Children's Sleep Habits Questionnaire, but not actigraph‐measured sleep efficiency, was predictive of parent and teacher behavioural concerns on the Nisonger Child Behaviour Rating Form and the Vanderbilt ADHD Rating Scales. Actigraph‐measured sleep period and parent‐reported sleep duration on the Children's Sleep Habits Questionnaire was predictive of daytime parent‐reported inattention. Actigraph‐measured sleep period was predictive of parent‐reported hyperactivity/impulsivity.ConclusionThe study findings suggest that sleep problems have complex relationships to both parent‐reported and teacher‐reported daytime behaviour concerns in children with Down syndrome. These findings have implications for understanding the factors impacting behavioural concerns and their treatment in school‐age children with Down syndrome.
The Spanish version of the Self‐Determination Inventory Student Report: application of item response theory to self‐determination measurement
Authors: Mumbardó‐Adam C. , Guàrdia‐Olmos J. , Giné C. , Raley S. K. , Shogren K. A. 
Published: December 2017

AbstractBackgroundA new measure of self‐determination, the Self‐Determination Inventory: Student Report (Spanish version), has recently been adapted and empirically validated in Spanish language. As it is the first instrument intended to measure self‐determination in youth with and without disabilities, there is a need to further explore and strengthen its psychometric analysis based on item response patterns.MethodThrough item response theory approach, this study examined item observed distributions across the essential characteristics of self‐determination.ResultsThe results demonstrated satisfactory to excellent item functioning patterns across characteristics, particularly within agentic action domains. Increased variability across items was also found within action‐control beliefs dimensions, specifically within the self‐realisation subdomain.ConclusionsThese findings further support the instrument's psychometric properties and outline future research directions.
Hepatocellular carcinoma in a free‐living marmoset (Callithrix sp.) with concomitant biliary trematodiasis
Authors: Díaz‐Delgado J. , Sanches T. C. , dos Santos‐Cirqueira C. , Coimbra A. A. C. , Guerra J. M. , Joppert A. , Di Loretto C. , Rizardi M. B. , Sansone M. , Nagamori F. O. , Gonçalves P. S. , Ressio R. , Iglezias S. , Fernandes N. C. C. A. , Kanamura C. , Groch K. R. , Catão‐Dias J. L. 
Published: December 2017

AbstractHepatocellular carcinoma (HCC) is rare in New World primates. We report the gross, microscopical, and immunocytochemical features of a spontaneous HCC in a free‐living marmoset (Callithrix sp.). Hepatitis B and C virus and aflatoxin immunohistochemistry were negative; however, concomitant intra‐ and extrahepatic biliary trematodiasis could have played a role.
The clustering and morphology of chondrocytes in normal and mildly degenerate human femoral head cartilage studied by confocal laser scanning microscopy
Authors: Karim Asima , Amin Anish K. , Hall Andrew C. 
Published: December 2017

AbstractChondrocytes are the major cell type present in hyaline cartilage and they play a crucial role in maintaining the mechanical resilience of the tissue through a balance of the synthesis and breakdown of extracellular matrix macromolecules. Histological assessment of cartilage suggests that articular chondrocytes in situ typically occur singly and demonstrate a rounded/elliptical morphology. However, there are suggestions that their grouping and fine shape is more complex and that these change with cartilage degeneration as occurs in osteoarthritis. In the present study we have used confocal laser scanning microscopy and fluorescently labelled in situ human chondrocytes and advanced imaging software to visualise chondrocyte clustering and detailed morphology within grade‐0 (non‐degenerate) and grade‐1 (mildly degenerate) cartilage from human femoral heads. Graded human cartilage explants were incubated with 5‐chloromethylfluorescein diacetate and propidium iodide to identify the morphology and viability, respectively, of in situ chondrocytes within superficial, mid‐ and deep zones. In grade‐0 cartilage, the analysis of confocal microscope images showed that although the majority of chondrocytes were single and morphologically normal, clusters (i.e. three or more chondrocytes within the enclosed lacunar space) were occasionally observed in the superficial zone, and 15–25% of the cell population exhibited at least one cytoplasmic process of ~ 5 μm in length. With degeneration, cluster number increased (~ 50%) but not significantly; however, the number of cells/cluster (P < 0.001) and the percentage of cells forming clusters increased (P = 0.0013). In the superficial zone but not the mid‐ or deep zones, the volume of clusters and average volume of chondrocytes in clusters increased (P < 0.001 and P < 0.05, respectively). The percentage of chondrocytes with processes, the number of processes/cell and the length of processes/cell increased in the superficial zone of grade‐1 cartilage (P = 0.0098, P = 0.02 and P < 0.001, respectively). Processes were categorised based on length (L0 – no cytoplasmic processes; L1 < 5 μm; 5 < L2 ≤ 10 μm; 10 < L3 ≤ 15 μm; L4 > 15 μm). With cartilage degeneration, for chondrocytes in all zones, there was a significant decrease (P = 0.015) in the percentage of chondrocytes with ‘normal’ morphology (i.e. L0), with no change in the percentage of cells with L1 processes; however, there were significant increases in the other categories. In grade‐0 cartilage, chondrocyte clustering and morphological abnormalities occurred and with degeneration these were exacerbated, particularly in the superficial zone. Chondrocyte clustering and abnormal morphology are associated with aberrant matrix metabolism, suggesting that these early changes to chondrocyte properties may be associated with cartilage degeneration.
Analytic survey of 57 cases of oral metastases
Authors: Liu Yingci , Vargo Richard J. , Bilodeau Elizabeth A. 
Published: December 2017

BackgroundOral lesions have been reported among the first signs of an undiagnosed metastatic disease. Accurate diagnosis of an occult metastasis remains critical in determining the treatment course. Previous studies regarding oral metastatic tumors present varied data regarding the most frequent metastases to the oral cavity. These discrepancies echo the changes in incidence rates for certain malignancies over time and demonstrate the need for periodic updates in oral metastasis studies.MethodsUsing Text Information Extraction System, a de‐identified pathology database, we compiled 57 cases over a period of 19 years using key terms to search for oral metastases.ResultsFor both males and females, the most common primary sites were lung (21.1%), liver (12.3%), breast (10.5%), kidney (10.5%), and colorectal (8.8%). We found an equal number of lung and breast metastases in females and metastases from the liver to be the most prevalent for males. In most of our cases (54.9%), the patient had no history of the primary malignancy and the oral lesion preceded awareness of the widespread cancer.ConclusionsAs a departure from many previous case series, we found lung and breast metastases to be equally numerous in women and liver as the most common oral metastasis in men. Also, we identified a tendency for the patient to present with a previous history in certain malignancies, such as breast cancer, whereas in other malignancies, such as renal cell carcinoma, our data demonstrated a propensity to present in the oral cavity without history of a primary tumor.
Fitting motivational content and process: A systematic investigation of fit between value framing and self‐regulation
Authors: Woltin Karl‐Andrew , Bardi Anat 
Published: December 2017

AbstractObjectiveValues are often phrased as ideals that people seek to approach, but they can also be conceptualized as counter‐ideals that people seek to avoid. We aimed to test whether individuals endorse more strongly values that are framed in line with their predominant self‐regulatory motivation, using individual difference scales in promotion/prevention (Higgins, 1997) and in behavioral approach/inhibition (Carver & White, 1994). To address this systematically, we developed approach‐ and avoidance‐framed versions of the Portrait Value Questionnaire‐RR (PVQ‐RR; Schwartz et al., 2012).MethodParticipants completed approach‐ and avoidance‐framed PVQ‐RR versions in two studies measuring regulatory focus or motivational orientation (together 414 U.S. adults, 48% female, ages 18–69) and one study manipulating motivational orientation (39 UK high school students, 79% female, ages 16–19).ResultsValue framing consistently interacted with both self‐regulation variables. However, a fit between self‐regulation and value framing resulted in greater value endorsement only for promotion‐focused and approach‐oriented (not prevention‐focused and avoidance‐oriented) participants. This may be because values are more naturally understood as ideal states that people seek to approach.ConclusionsOur findings provide first insights into the psychological process of person–value framing fit affecting value endorsement. We discuss implications for cross‐cultural value research and research on value‐congruent behavior.
The work and challenges of care managers in the implementation of collaborative care: A qualitative study
Authors: Overbeck G. , Kousgaard M. B. , Davidsen A. S. 
Published: December 2017

Accessible summaryWhat is known on the subject?

In collaborative care models between psychiatry and general practice, mental health nurses are used as care managers who carry out the treatment of patients with anxiety or depression in general practice and establish a collaborating relationship with the general practitioner. Although the care manager is the key person in the collaborative care model, there is little knowledge about this role and the challenges involved in it.

What this paper adds to existing knowledge?

Our study shows that before the CMs could start treating patients in a routine collaborative relationship with GPs, they needed to carry out an extensive amount of implementation work. This included solving practical problems of location and logistics, engaging GPs in the intervention, and tailoring collaboration to meet the GP’s particular preferences.

Implementing the role requires high commitment and an enterprising approach on the part of the care managers. The very experienced mental health nurses of this study had these skills. However, the same expertise cannot be presumed in a disseminated model.

What are the implications for practice?

When introducing new collaborative care interventions, the care manager role should be well defined and be well prepared, especially as regards the arrival of the care manager in general practice, and supported during implementation by a coordinated leadership established in collaboration between hospital psychiatry and representatives from general practice.

AbstractIntroductionIn collaborative care models for anxiety and depression, the care manager (CM), often a mental health nurse, has a key role. However, the work and challenges related to this role remain poorly investigated.AimTo explore CMs’ experiences of their work and the challenges they face when implementing their role in a collaborative care intervention in the Capital Region of Denmark.MethodsInterviews with eight CMs, a group interview with five CMs and a recording of one supervision session were analysed by thematic analysis.ResultsThe CM carried out considerable implementation work. This included finding suitable locations; initiating and sustaining communication with the GPs and maintaining their engagement in the model; adapting to the patient population in general practice; dealing with personal security issues, and developing supportive peer relations and meaningful supervision.DiscussionWe compare our findings to previous studies of collaborative care and advanced nursing roles in general practice. The importance of organizational leadership to support the CM's bridge‐building role is emphasized.Implications for practiceThe planners of new collaborative care interventions should not only focus on the CM's clinical tasks but also on ensuring the sufficient organizational conditions for carrying out the role.
Valve morphogenesis in Diploneis smithii (Bacillariophyta)
Authors: Idei Masahiko , Sato Shinya , Tamotsu Nagumo , Mann David G. 
Published: December 2017

Diploneis species have perhaps the most complex valve structure among pennate diatoms. The development of this structure was studied in Diploneis smithii and begins with the formation of a primary band, which then develops secondary arms at both poles and the center, as in the classic Chiappino–Volcani model of raphid diatom ontogeny. Spine‐like projections grow out from the primary band and secondary arms to establish the transapical ribs (virgae) of the mature valve and themselves develop spines, which are spaced first oppositely and then alternately and fuse with each other to delimit the stria pores. Subsequently, new pattern and structures develop both externally (formation of bifurcating projections that fuse to delimit the outer, sieve‐like layer of the valve) and internally (growth and fusion of flanges from the first‐formed ribs to create the longitudinal canals and deposition of a hymenate strip over the internal face of each stria). Comparisons are made with morphogenesis in other diatoms. Diploneis smithii ontogeny suggests how very slight developmental changes might have created the very variable external morphology of Diploneis species. It also indicates that the longitudinal canals of Diploneis and Fallacia have different origins, since the porous external wall is not formed as a unilaterally attached flap in Diploneis and the canal is internal to the first‐formed rib–stria system in Diploneis, but external to it in Fallacia.
Effect of Continuous Digital Hypothermia on Lamellar Inflammatory Signaling When Applied at a Clinically‐Relevant Timepoint in the Oligofructose Laminitis Model
Authors: Dern K. , van Eps A. , Wittum T. , Watts M. , Pollitt C. , Belknap J. 
Published: December 2017

BackgroundAlthough continuous digital hypothermia (CDH) protects lamellae from injury in the oligofructose (OF) model of sepsis‐related laminitis (SRL), conflicting results exist from these studies regarding effects of CDH on lamellar inflammatory events.Hypothesis/ObjectivesTo determine the effect of CDH on lamellar inflammatory events in normal and OF‐treated horses when instituted at a clinically relevant time point (onset of clinical signs of sepsis in this model).AnimalsStandardbred geldings (n = 15) aged 3–11 years were used.MethodsIn a randomized, controlled discovery study, animals were administered either OF (OF group, n = 8) or water (CON group, n = 8) by nasogastric tube and CDH was initiated in one forelimb (ICE) 12 hours later. Lamellar tissue samples were collected 24 hours after initiation of CDH (ICE and ambient [AMB] forelimbs). Lamellar mRNA concentrations of inflammatory mediators and lamellar leukocyte numbers were assessed using qPCR and immunohistochemistry, respectively; values from four sample groups (CON AMB, OF AMB, CON ICE, and OF ICE) were analyzed using mixed model linear regression.ResultsAlthough lamellar mRNA concentrations of multiple inflammatory mediators (IL‐1β, IL‐6, CXCL1, MCP2, COX‐2) were increased after OF administration (OF AMB group versus CON AMB; P < 0.05), only 2 inflammatory mediators (IL‐6 and COX‐2) and lamellar leukocyte numbers were decreased with CDH (OF ICE versus OF AMB; P < 0.05).Conclusions and Clinical ImportanceContinuous digital hypothermia initiated at a time point similar to that commonly used clinically (clinical onset of sepsis) resulted in a more focused inhibition of inflammatory signaling.
Proportion of fine roots, but not plant biomass allocation below ground, increases with elevation in arctic tundra
Authors: Blume‐Werry Gesche , Lindén Elin , Andresen Lisa , Classen Aimée T. , Sanders Nathan J. , von Oppen Jonathan , Sundqvist Maja K. 
Published: December 2017

AbstractQuestionsRoots represent a considerable proportion of biomass, primary production and litter input in arctic tundra, and plant allocation of biomass to above‐ or below‐ground tissue in response to climate change is a key factor in the future C balance of these ecosystems. According to optimality theory plants allocate C to the above‐ or below‐ground structure that captures the most limiting resource. We used an elevational gradient to test this theory and as a space‐for‐time substitution to inform on tundra carbon allocation patterns under a shifting climate, by exploring if increasing elevation was positively related to the root:shoot ratio, as well as a larger plant allocation to adsorptive over storage roots.LocationArctic tundra heath dominated by Empetrum hermaphroditum close to Abisko, Sweden.MethodsWe measured root:shoot and fine:coarse root ratios of the plant communities along an elevational gradient by sampling above‐ and below‐ground biomass, further separating root biomass into fine (<1 mm) and coarse roots.ResultsPlant biomass was higher at the lower elevations, but the root:shoot ratio did not vary with elevation. Resource allocation to fine relative to coarse roots increased with elevation, resulting in a fine:coarse root ratio that more than doubled with increasing elevation.ConclusionsContrary to previous works, the root:shoot ratio along this elevational gradient remained stable. However, communities along our study system were dominated by the same species at each elevation, which suggests that when changes in the root:shoot ratio occur with elevation these changes may be driven by differences in allocation patterns among species and thus turnover in plant community structure. Our results further reveal that the allocation of biomass to fine relative to coarse roots can differ between locations along an elevational gradient, even when overall above‐ vs below‐ground biomass allocation does not. Given the functionally different roles of fine vs coarse roots this could have large implications for below‐ground C cycling. Our results highlight the importance of direct effects vs indirect effects (such as changes in plant community composition and nutrient availability) of climate change for future C allocation above and below ground.
Romantic Ecocriticism Lately
Authors: Nersessian Anahid 
Published: December 2017

AbstractThis article surveys studies in Romanticism over the course of the last decade, focusing particularly on work that engages what might loosely be called ecological concerns. In contrast to standard accounts of “ecocriticism,” however, it holds that the most generative work being done in this field and, with these interests at heart, is not explicitly ecocritical. Instead, the article finds in the rhetorically attentive contributions of Romanticist scholars a kind of by‐the‐way environmentalism that remains admirably cautious about the consequences of a literary criticism deemed activist in and of itself. Building on Merleau‐Ponty's concept of the phantom limb, and on Veronica Forrest‐Thomson's critique of reflexively “naturalized” and mimetic interpretations of poetic texts, the discussion groups together critics who adopt and develop what I refer to as a phenomenological formalism. It then pursues the ramifications of this disciplinary turn in very recent works of scholarship situated in the 18th century and Romantic period.