bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk prediction model of physical frailty for a rural older population: a cross-sectional study in Hunan Province, China
Authors: Guo Xiuyan , Shi Chunhong 
Published: February 2025

IntroductionPhysical frailty is a common medical syndrome characterized by low muscle strength, low endurance, and reduced physiological function that leads to significantly negative health outcomes in older adults. This study investigated the risk variables among rural older adults in Hunan Province, China, and developed a physical frailty prediction model to inform policymaking to enhance their health and well-being.MethodsThis study was conducted from July 22 to September 3, 2022. A total of 291 participants were recruited using stratified cluster random sampling from five large villages in Hunan Province. Frailty screening was performed based on the Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale, Geriatric Depression Scale 15-item version (GDS-15), Falls Efficacy Scale-International (FES-I), and Mini Nutrition Assessment-Short Form (MNA-SF). A logistic regression analysis was performed to identify the predictive factors for physical frailty and develop a physical frailty prediction model based on the area under the receiver operating characteristic (ROC) curve (AUC), sensitivity, specificity, and Youden index.ResultsThe physical frailty prevalence among rural older adults in Hunan Province was 21.31% (n = 62). Household income and expenditure [odds ratio (OR): 1.826, 95% confidence interval (CI): 1.142–2.918], physical exercise frequency (OR: 1.669, 95% CI: 1.137–2.451), depressive symptoms (OR: 9.069, 95% CI: 3.497–23.516), and fear of falling (OR: 3.135, 95% CI: 1.689–5.818) were identified as significant predictors of physical frailty in rural older individuals. The AUC for the frailty predictive model was 0.860 (95% CI: 0.805, 0.914). The sensitivity and specificity at the optimal cutoff value were 80.6 and 76.0%, respectively, with a Youden index of 0.566.ConclusionThe prediction model constructed in this study demonstrated promise as a potential tool for evaluating physical frailty risk in older adults, which can contribute to healthcare providers’ screenings for high-risk populations. Further multidimensional and experimental intervention studies should be conducted to prevent the occurrence and delay the progression of physical frailty in older adults.
Global burden of trichomoniasis: current status, trends, and projections (1990–2021)
Authors: Wei Xingmin , Liu Lu , Liu Kun , Qin Xiaoang , Wu Jianjun , Jiang Lou , Shang Longjian 
Published: February 2025

ObjectivesTrichomoniasis one of the most neglected sexually transmitted diseases (STDs), imposes a significant global disease burden. This study aims to assess the burden and trends of trichomoniasis from 1990 to 2021 and to project its incidence from 2022 to 2050.MethodsThis study utilized data from the Global Burden of Disease 2021 study for secondary analysis. We determined the age-standardized incidence rate (ASIR) and disability-adjusted life years (DALYs) of trichomoniasis by sex, age, and socio-demographic index (SDI) level. Changes in burden trends across sex and age were explored from 1990 to 2021, using joinpoint regression. The incidence of trichomoniasis was projected for the period 2022 to 2050, using R software.ResultsFrom 1990 to 2021, the estimated annual percentage change (EAPC) in the global ASIR of trichomoniasis was 0.09 (95% CI: 0.06 to 0.13). In 2021, the global ASIR of trichomoniasis was 4,133.41 per 100,000 people (95% UI: 3,111.37 to 5,583.56 per 100,000). By population group, the ASIR was higher in men (4,353.43 per 100,000) than in women (3,921.31 per 100,000) in 2021, while the DALY rate was significantly higher in women than in men (6.45 vs. 0.23 per 100,000). When divided by age groups, the trend in ASIR among women aged 30–54 years aligned closely with the overall population incidence trend. In 2021, ASIRs were highest in low SDI regions, and the projected ASIRs by 2050 are 5,680.57 per 100,000 in males and 5,749.47 per 100,000 in females.ConclusionTrichomoniasis represents a significant global disease burden, particularly among women in low-income areas and individuals aged 30–54 years. The study highlights the need for targeted strategies to reduce the burden of trichomoniasis-related infections, especially in vulnerable populations.
High-throughput, pan-leukocyte biomarkers for the detection of inflammation in human breastmilk and stool
Authors: Dunnet M. J. , Morison I. M. , Bond D. M. , Hore T. A. 
Published: February 2025

BackgroundDNA methylation can be used to track cellular identity. We have previously developed a high-throughput, cost-effective DNA methylation pipeline containing two loci, HOXA3 and MAP4K1, that can quantify leukocyte proportion amongst a range of background tissues. Here, we apply this pipeline to two clinically relevant tissue samples: breastmilk and stool.ResultsWe report that our leukocyte methylation assay can quantify the proportion of leukocytes in breastmilk, and find leukocyte levels fluctuate dramatically in concert with infection severity. We benchmarked our leukocyte methylation pipeline in stool samples against the commonly used faecal calprotectin assay. Our results show a high concordance between the two methods indicating the viability of our DNA methylation biomarkers in the context of intestinal inflammation.Conclusion:The data presented here emphasise the clinical applicability of our high-throughput DNA methylation assay in the context of mastitis and intestinal inflammation.
Comparison of bacterial vaginosis symptoms reported in social media vs. those reported by patients
Authors: Velmahos Andriana H. , Cooley Demidkina Briah , Mitchell Caroline M. 
Published: February 2025

IntroductionThere is an increasing tendency to seek health information online rather than through medical professionals. However, the easy accessibility of information online allows for an increased risk of encountering medical misinformation.MethodsWe compared descriptions of symptomatology of bacterial vaginosis (BV) on four social media platforms: Instagram, Facebook, YouTube and X (Twitter). We then compared the frequency of discussion of symptoms with patients' report of symptoms in clinically diagnosed BV, vulvovaginal candidiasis and vulvodynia.ResultsSocial media was more likely to report burning (45% of posts), itching (45%) or pain (23%) as symptoms of BV than patients (moderate-severe itching 30%, burning 21% or pain 21%). Although pain was reported more often by people with vulvodynia, other symptoms were not different across diagnoses.DiscussionSocial media overemphasizes the ability of symptoms to allow self-diagnosis of vaginitis, which can lead to delayed treatment, highlighting the need to promote accurate health information online.
Digital economy, consumption structure and rural economic transformation: a case study of China
Authors: Liu Yang , Chen Wenjuan , Zhang Xu , Liao Wenmei 
Published: February 2025

IntroductionPromoting rural economic transformation is an important foundation for achieving agricultural modernization. Under the background of rural revitalization strategy, digital technology is increasingly being applied in the agricultural sector, and the digital economy is becoming a new driving force for China's rural economic transformation.MethodsBased on China's provincial panel data from 2013 to 2020, this paper uses the two-way fixed effect model, intermediary effect model, and panel threshold model to deeply analyze the impact and internal mechanism of the digital economy development on rural economic transformation.Results and discussionThe research shows that the digital economy significantly promotes China's rural economic transformation, and this conclusion is still valid after robustness tests such as selecting historical data as instrumental variables. The mechanism test confirms that the digital economy promotes rural economic transformation by optimizing residents' consumption structure. In addition, the digital economy has a single threshold effect on the rural economic transformation based on the level of consumption structure. After crossing the threshold value, its promotion effect on the rural economic transformation is more prominent, indicating that the impact of the digital economy on the rural economic transformation will show the non-linear characteristics of increasing ‘marginal effect' due to the different levels of consumption structure; Heterogeneity analysis found that compared to southern regions, the digital economy in northern regions has a more significant promoting effect on rural economic transformation. This study deepens the understanding of the motivation for rural economic transformation and the effects, mechanisms, and regional differences of the digital economy empowering rural economic transformation. Based on this, this paper proposes that the government fully realize the digital economy's important role in rural economic transformation, actively innovate and promote digital technology, continue to expand and strengthen the consumer Internet, adjust measures to local conditions, and try to achieve coordinated development.
Mortality Outcome Associated with Specific KRAS, NRAS, and BRAF Hot-Spot Mutations in Metastatic Colorectal Cancer Patients: A Retrospective Cohort Study
Authors: Abdelgadir Omer , Kuo Yong-Fang , Khan M. Firoze , Okorodudu Anthony O. , Cheng Yu-Wei , Dong Jianli 
Published: February 2025

Background/Objective: The prognostic value of specific hot-spot mutations within KRAS, NRAS, and BRAF genes in metastatic colorectal cancer (mCRC) genes remains debatable. This study explores whether certain KRAS, NRAS, and BRAF mutations are associated with the risk of all-cause mortality in mCRC. Methods: We retrospectively analyzed records of 494 patients with mCRC treated at the University of Texas Medical Branch between January 2016 and July 2023. Data on genetic mutations and clinicopathological features were collected for this analysis. We estimated survival probabilities and conducted multivariable Cox proportional hazards regression to evaluate the impact of specific mutations on all-cause mortality risk. Results: KRAS c.35G>T (p.Gly12Val) and c.34G>T (p.Gly12Cys) mutations were significantly associated with an increased risk of all-cause mortality in the overall mCRC population and the treated mCRC subgroup. KRAS c.38G>A (p.Gly13Asp) was significantly associated with an increased risk of all-cause mortality in the treated mCRC subgroup but BRAF c.1799T>A (p.Val600Glu) was significantly associated with an increased risk of all-cause mortality in the overall mCRC population. No significant association was observed between NRAS mutations and mortality risk in mCRC, possibly due to their lower frequency or different biological effects compared to KRAS and BRAF mutations. Conclusions: These findings suggest that specific KRAS [c.35G>T (p.Gly12Val), c.34G>T (p.Gly12Cys), and c.38G>A (p.Gly13Asp)] and BRAF c.1799T>A (p.Val600Glu) mutations may have prognostic value in mCRC. However, given the single-center study design and lack of direct therapeutic implications, larger multicenter studies are needed to substantiate these results and better define the clinical relevance of these mutations.
New Combination and Two Synonyms of Indocalamus Nakai (Poaceae: Bambusoideae) from China Based on Morphological Characters and Phylogenetic Evidence
Authors: Gao Liqin , Li Yonglong , Wang Chengkun , Wang Jianqing , Yang Guangyao , Zhang Wengen 
Published: February 2025

Based on several sources of evidence from morphology, the micromorphology of the abaxial leaf epidermis, and a phylogenetic analysis using complete chloroplast genome data, a new combination and two new synonyms are reported in the genus Indocalamus Nakai. Indocalamus cordatus T. H. Wen et Y. Zou is synonymized with I. tessellatus (Munro) P. C. Keng, and I. multinerus (W. T. Lin et Z. M. Wu) W. T. Lin is synonymized with I. chebalingensis W. T. Lin. As a new combination, I. mollis (H. R. Zhao et Y. L. Yang) L. Q. Gao, W. G. Zhang et G. Y. Yang was created and is supplementally described. In addition, the lectotype of I. chebalingensis is designated herein.
Online Food Delivery Apps in the Modern Era: A Contemporary Perspective
Authors: Madhuritha M , Nedumaran G 
Published: February 2025

Online food ordering is one of the fastest-growing sectors of the Indian e-commerce market. Online ordering is perhaps the easiest and most convenient option whether through a fast food chain’s website or mobile application, or a site or app that offers more options for food delivery from various eateries. The platforms offer varieties of cuisines like fast food, Indian, Chinese, Italian, and more. In these days, the culture of eating out is replaced by the culture of eating in. Due to this, it is seen that more Indian households have online food delivery services. The best well-known food online delivery services include Zomato, Swiggy, Food Panda, and many more. This paper is conceptual in nature and mainly deals with the Notion of OFD Apps, Role of OFD Apps in current Scenario, various technologies adopted by online food delivery apps, Copious business models and revenue streams of Zomato, SWOT analysis and the future of Online food apps and their potential innovations.
Оценка огнезащитной эффективности лакокрасочного покрытия при его эксплуатации
Authors: Аносова Е.Б. , Фатыхов Р.Р. , Ерёмина Ж.Ю. 
Published: February 2025

Для огнезащиты строительных конструкций, изготовленных из древесины, широкое распространения получили лакокрасочные материалы. Механизм их действия может быть связан с поведением при термическом воздействии. В зависимости от состава, огнезащитные лакокрасочные материалы при термическом воздействии образуют плотный несгораемый слой, или же проявляют интумесцентные свойства. Интумесцентные огнезащитные составы, многократно увеличивающиеся при тепловом воздействии и образующие негорючий пенно-коксовый слой, являются наиболее распространенными и эффективными покрытиями. Для подтверждения интумесцентного действия у исследованного образца интерьерной огнезащитной краски по дереву был проведен эксперимент с использованием синхронного термического анализа (СТА). Данный метод анализа является одним из информативных и точных инструментальных методов, позволяющих решить широкий круг задач, связанных с изучением воздействия повышенной температуры и пламени пожара. Характеристики образцов лакокрасочных материалов, полученные с применением СТА: температура, соответствующая степени превращения материала, скорость уменьшения массы при повышенной температуре, зольный остаток, наличие экзотермических эффектов на кривой ДСК, позволяют предположить механизм огнезащиты ЛКП. Использование искусственно состаренных образцов краски, наряду со свеженанесенными, позволяет оценить эксплуатационные свойства лакокрасочного материала, рекомендованного к оптово-розничной продаже в России.
For fire protection of building structures made of wood, paint and varnish materials are widely used. The mechanism of their action may be related to the behavior of thermal exposure. Depending on the composition, flame-retardant paints and varnishes form a dense fireproof layer under thermal exposure, or exhibit intumescent properties. Intumescent flame retardants, which multiply under thermal influence and form a non-flammable foam-coke layer, are the most common and effective coatings. To confirm the intumescent effect of the studied sample of interior flame retardant paint on wood, an experiment was conducted using synchronous thermal analysis (STA). This method of analysis is one of the informative and accurate instrumental methods that allow solving a wide range of tasks related to the study of the effects of elevated temperature and fire flames. Characteristics of the sample obtained with the use of STA: the temperature corresponding to the degree of transformation of the material, the rate of mass reduction at elevated temperature, ash residue, the presence of exothermic effects on the DSC curve, suggest the mechanism of fire protection of the paints and varnishes form. The using of artificially aged paint samples, along with freshly applied ones, allows us to evaluate the performance properties of the paint and varnish material recommended for wholesale and retail sale in Russia.
KAITAN INTELLECTUAL CAPITAL TERHADAP RASIO PROFITABILITAS PERUSAHAAN INDUSTRI BARANG KONSUMSI YANG TERDAFTAR DI BURSA EFEK INDONESIA PADA PERIODE 2014-2015
Authors: Dermawan Elizabeth Sugiarto 
Published: February 2025

ABSTRACT This study aimed to investigate the association Intellectual Capital and profitability ratios consumer goods industries listed in the Indonesia Stock Exchange (BEI) in the period 2014-2015. Intellectual Capital is measured by the Value Added Intellectual Coefficient (VAIC) and the company’s financial performance is measured by Return on Assets (ROA). Hypothesis testing cross section data in this study using multiple linear regression model with a significance level of 5%. F test results showed that the VACA, VAHU, and STVA have significant influence jointly on profitability ratios. The results of this study also concluded that the cross section partially only VAHU consistent positive significantly effect on the profitability ratio (ROA), while VACA and STVA consistent no significantly effect on the profitability ratio (ROA). In time series data is not normal so that the study was tested with non-parametric test. Data hypothesis testing time series with Spearman’s Rho show a correlation between VACA, VAHU, and STVA entirely significant positive to ROA. Keywords: intellectual capital, profitability ratio, consumer goods industry. ABSTRAK Penelitian ini bertujuan untuk menginvestigasi kaitan Intellectual Capital terhadap rasio profitabilitas perusahaan industri barang konsumsi yang terdaftar di Bursa Efek Indonesia (BEI) pada periode 2014-2015. Intelectual Capital diukur dengan Value Added Intellectual Coefficient (VAIC) dan kinerja keuangan perusahaan diukur dengan Return on Asset (ROA). Uji hipotesis data cross section dalam penelitian ini menggunakan model regresi linear berganda dengan tingkat signifikansi sebesar 5%. Hasil uji F menunjukkan bahwa VACA, VAHU, dan STVA mempunyai pengaruh yang signifikan secara bersama-sama terhadap rasio profitabilitas perusahaan. Hasil penelitian ini secara cross section juga menyimpulkan bahwa secara parsial hanya VAHU konsisten berpengaruh signifikan terhadap rasio profitabilitas (ROA), sedangkan VACA dan STVA konsisten tidak berpengaruh signifikan terhadap rasio profitabilitas (ROA). Secara timeseries data penelitian ini tidak normal sehingga diuji dengan uji non parametrik. Uji hipotesis data timeseries dengan Spearman’s Rho menunjukkan kaitan VACA, VAHU, dan STVA yang seluruhnya signifikan positif terhadap ROA. Kata Kunci: modal intelektual, rasio profitabilitas, sektor industri barang konsumsi.
KETERKAITAN ANTARA SISTEM PENGENDALIAN MANAJEMEN, SET KESEMPATAN INVESTASI, INOVASI, KINERJA DAN KEBIJAKAN AKUNTANSI
Authors: Mulya Ali Sandy , Mayangsari Sekar 
Published: February 2025

ABSTRACT This study aimed to analyze several causal relationship between several variables. First, the influence of management control systems, innovation, investment opportunity set on financial performance. Second, the influence of innovation, management control system and performance on investment opportunity set. Last, the influence of performance on the choice of accounting policies. The samples were used 151 respondents from listed companies. The results showed that only management control systems give influence on financial performance, while innovation and investment opportunity set do not influence on financial performance. The other results show that performance influence on accounting policies. Furthermore, innovation, management control system and performance do not affect investment opportunity set. Keywords: management control system, investment opportunities set, innovation, financial performance, accounting policies. ABSTRAK Penelitian ini bertujuan untuk menganalisis pengaruh inovasi, sistem pengendalian manajemen, dan set kesempatan inovasi terhadap kinerja. Penelitian ini juga menganalisis pengaruh inovasi, sistem pengendalian manajemen dan kinerja pada set kesempatan investasi. Terakhir, penelitian ini ingin menguji pengaruh set kesempatan investasi pada kinerja. Sampel yang digunakan adalah perusahaan publik. Hasil penelitian menunjukkan bahwa sistem pengendalian manajemen berpengaruh signifikan pada kinerja, sedangkan inovasi dan set kesempatan investasi tidak berpengaruh pada kinerja. Hasil lain menunjukkan bahwa inovasi, sistem pengendalian manajemen dan kinerja tidak mempengaruhi set kesempatan investasi. Terakhir, kinerja perusahaan berpengaruh signifikan pada pemilihan kebijakan akuntansi. Kata Kunci: sistem pengendalian manajemen, set kesempatan investasi, inovasi, kinerja, kebijakan akuntansi.
Edipo, mito y realidad
Authors: Rebella Griselda 
Published: February 2025

La autora intenta vincular los mitos narrados en la Antigüedad que han jalonado la historia del psicoanálisis, particularmente elde Edipo, con expresiones de la cultura de la época cuyas trazas marcan hoy un pensamiento cuestionador hacia sus lados vigentes,cuestionables, obsoletos o en transformación. Así como los bardos tomaban parte de la verdad del hecho y lo transformaban como argamasa en sus manos, llegando evolucionados acorde a cada época, hasta nuestros días, hoy no podemos hacer a un lado los cambios y transformaciones sucesivas en la configuración familiar con las familias adoptivas, monoparentales, gays, «recompuestas», etc., que nos exigen seguir investigando. ¿Sigue siendo el complejo de Edipo el nuclear de las neurosis? ¿Qué lugar le damos hoy a lo transgeneracional? ¿Dónde ubicamos la culpa freudiana?Se plantea lo efímero de las verdades construidas que una y otra vez relanzan nuevos movimientos. Desde Freud, con las oscuridades acerca de las diferencias de vivencias edípicas entre géneros, hasta nuestros días, donde parece más adecuado hablar de funciones estructurantes, la autora toma conceptos de otros autores para pensar parcialmente algunas de las vicisitudes actuales acerca del tema.
Emotional Intelligence and Its Effect on Person-Centered Care: A Qualitative Study of Nursing Professionals in Jordan
Authors: Batiha Abdul-Monim 
Published: February 2025

Background
Emotional intelligence (EI) is increasingly recognized as a critical factor in health care, enhancing empathy, communication, and patient outcomes. However, its specific role in promoting person-centered care (PCC) in culturally diverse settings, such as Jordan, is underexplored. This study investigates the qualitative impact of EI on PCC among Jordanian nursing professionals.

Method
This qualitative study employed thematic analysis of focus group discussions with 30 nursing professionals. Braun and Clarke's six-step framework guided the analysis, identifying themes related to the influence of EI on PCC practices.

Results
The analysis identified four primary themes: enhanced empathy, improved teamwork, effective conflict resolution, and positive patient outcomes. Participants described how EI enabled culturally sensitive interactions, strengthened nurse-patient trust, and fostered collaboration among health care teams.

Conclusion

The findings highlight the integral role of EI in delivering PCC. Incorporating EI training into nursing education and professional development can increase empathy, teamwork, and culturally responsive patient care.

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J Contin Educ Nurs.
2025;56(3):119–124.]