bluuebunny/crossref_metadata_2025_split huggingface dataset:
Suicides par intoxication dans la région de Souss-Massa-Drâa au Maroc
Authors: Mahir Siham , Soulaymani Abdelmajid , Hami Hind , Mokhtari Abdelrhani , Benali Doha , Ouammi Lahcen , Windy Maria , Bencheikh Rachida Soulaymani 
Published: October 2017

Introduction ?: la région de Souss-Massa-Drâa est l’une des régions du Maroc concernée par la problématique des intoxications suicidaires et les dimensions exactes de ce phénomène sont encore mal dégagées. Objectif ?: la présente étude vise à décrire les caractéristiques des patients, des toxiques suspectés et des intoxications et déterminer les facteurs de risque qui peuvent influencer l’évolution des patients. Méthodes ?: il s’agit d’une étude rétrospective de tous les cas d’intoxications suicidaires répertoriés entre 1981 et 2007 par le Centre Anti Poison et de Pharmacovigilance du Maroc. Résultats ?: durant la période d’étude, 1 130 cas d’intoxications suicidaires ont été colligés. L’âge moyen des victimes était de 25 ± 10,1 ans avec un sex-ratio (M/F) de 0,4. Le nombre de décès le plus élevé a été enregistré chez les patients intoxiqués par la paraphénylène diamine (48 décès) suivi par l’acide chlorhydrique (15 décès). L’étude de la corrélation montre une forte liaison entre l’évolution vers la guérison et les femmes appartenant au groupe d’âge d’adolescent d’une part, et d’autre part entre l’évolution vers le décès et les hommes appartenant aux autres groupes d’âge. Les patients intoxiqués par la paraphénylène diamine ont douze fois plus de risque d’évoluer vers le décès (IC95 %?: 7,4 % - 19,2 %) que ceux intoxiqués par d’autres produits toxiques. Les signes respiratoires et cardiovasculaires étaient les plus associés au décès avec un risque de 9,8 (IC95 %?: 6,3 % - 15,9 %) et 3,6 (IC95 %?: 2,3 % - 5,7 %). Parmi les 937 cas pour lesquels l’évolution est connue, 89 sont décédés, soit 9,5 %.
Épidémiologie et facteurs de risque des intoxications volontaires au Mali
Authors: Diallo Tidiane , Hami Hinde , Maiga Ababacar , Coulibaly Boubou , Maiga Diadié , Mokhtari Abdelrhani , Soulaymani Rachida , Soulaymani Abdelmajid 
Published: October 2017

Introduction  : l’intoxication volontaire est un problème médical et social majeur des pays en voie de développement. Le but de cette étude était de décrire les caractéristiques épidémiologiques et cliniques des intoxications aigües volontaires au Mali, ainsi que les facteurs de risque liés à l’évolution de ces intoxications, en vue de diminuer la morbidité et la mortalité liées à cette problématique. Méthodes  : une étude rétrospective des cas d’intoxications volontaires, enregistrés entre 2000 et 2010, dans les dossiers médicaux et les registres de consultation des 15 hôpitaux au Mali, a été réalisée. Résultats  : pendant la période d’étude, 884 cas d’intoxication (233 hommes et 651 femmes) ont été identifiés, soit 28 % de l’ensemble des intoxications déclarées durant la même période. L’âge moyen de victimes était de 23 ± 8,9 ans. Selon nos résultats, les tentatives de suicide et l’avortement par l’ingestion volontaire de produits toxiques sont les circonstances les plus communes (respectivement 62,8 % et 29 % de cas). Les médicaments sont les principaux produits employés par les victimes (74,5 %), particulièrement la chloroquine (65 %), suivis par des produits industriels (9,1 %). Les produits industriels utilisés sont l’acide hydrochlorique (26,7 %), l’hypochlorite sodium (l’eau de javel) (22,2 %) et l’acide sulfurique (15,6 %). Les symptômes d’empoisonnement variaient selon les substances impliquées, la quantité ingérée et le retard de traitement. Parmi les 877 cas dont l’évolution était connue, 86 d’entre eux sont décédés. Conclusion  : le nombre réel d’intoxication volontaire est probablement sous-estimé, à cause des cas non diagnostiqués et non signalés.
Bioclimatic approach to assessing factors influencing shifts in geographic distribution and relative abundance of two flea beetle species (Coleoptera: Chrysomelidae) in North America
Authors: Olfert O. , Weiss R.M. , Soroka J.J. , Elliott R.H. 
Published: October 2017

AbstractCrucifer flea beetle, Phyllotreta cruciferae (Goeze) and striped flea beetle, Phyllotreta striolata (Fabricius) (Coleoptera: Chrysomelidae) are the most chronic and economically important flea beetle pests of cruciferous (Brassicaceae) crops in western Canada. There have been reports that populations of P. striolata are increasing in numbers and expanding their geographic range. Climate is the fundamental factor regulating the distribution and abundance of most insect species. Bioclimate simulation models of the two flea beetle species were developed to assess climatic factors influencing shifts in their geographic distribution and density. The results fostered a better understanding of how the two species responded to selected climate variables. Growing seasons with above average precipitation were predicted to favour the geographic distribution of P. striolata more than P. cruciferae. Both P. cruciferae and P. striolata were sensitive to temperature changes in the range of −2 °C to +2 °C. The ecoclimatic index (suitability index) for P. cruciferae increased with increasing temperatures, whereas the index for P. striolata declined with increasing temperatures. This study highlights the regions of the Prairies and Boreal Plains Ecozones that are most sensitive to shifts of the two populations and which may require changes in insecticidal seed treatments for effective control.
Naringenin Ameliorates Acute Inflammation by Regulating Intracellular Cytokine Degradation
Authors: Jin Lingtao , Zeng Wenfeng , Zhang Fayun , Zhang Chunling , Liang Wei 
Published: October 2017

Abstract
Ungoverned activation of innate and adaptive immunity results in acute inflammatory disease, such as bacteria-induced endotoxemia and fulminant hepatitis by virus infection. Thus, therapeutic control of inflammation is crucial for clinical management of many human diseases. In murine models of LPS- and Con A–induced liver injury, we found that naringenin, a natural predominant flavanone, is capable of protecting against lethality induced by LPS and preventing inflammation-induced organ injury. The protective effect of naringenin is mediated by reducing the levels of several inflammatory cytokines. Unexpectedly, naringenin inhibits TNF-α and IL-6 secretion in macrophages and T cells without interfering with the TLR signaling cascade, cytokine mRNA stability, or protein translation. These results indicate the existence of a posttranslational control mechanism. Further studies show that naringenin enhances intracellular cytokine degradation through lysosome- and TFEB-dependent mechanisms. This study provides evidence that naringenin has the capacity to dampen cytokine production by regulating lysosome function. Thus, naringenin may represent a potential therapeutic agent for controlling inflammation-related diseases.
Mechanisms of the Innate Defense Regulator Peptide-1002 Anti-Inflammatory Activity in a Sterile Inflammation Mouse Model
Authors: Wu Bing Catherine , Lee Amy Huei-Yi , Hancock Robert E. W. 
Published: October 2017

Abstract
Innate defense regulator (IDR) peptide-1002 is a synthetic host defense peptide derivative with strong anti-inflammatory properties. Extending previous data, IDR-1002 suppressed in vitro inflammatory responses in RAW 264.7 murine monocyte/macrophage cells challenged with the TLR4 agonist LPS and TLR2 agonists lipoteichoic acid and zymosan. To investigate the anti-inflammatory mechanisms of IDR-1002 in vivo, the PMA-induced mouse ear inflammation model was used. Topical IDR-1002 treatment successfully dampened PMA-induced ear edema, proinflammatory cytokine production, reactive oxygen and nitrogen species release, and neutrophil recruitment in the ears of CD1 mice. Advanced RNA transcriptomic analysis on the mouse ear transcriptome revealed that IDR-1002 reduced sterile inflammation by suppressing the expression of transmembrane G protein–coupled receptors (class A/1 rhodopsin-like), including receptors for chemokines, PGs, histamine, platelet activating factor, and anaphylatoxin. IDR-1002 also dampened the IFN-γ response and repressed the IFN regulatory factor 8–regulated network that controls central inflammatory pathways. This study demonstrates that IDR-1002 exhibits strong in vitro and in vivo anti-inflammatory activities, informs the underlying anti-inflammatory mechanisms, and reveals its potential as a novel therapeutic for inflammatory diseases.
Modeling of the chemistry in oxidation flow reactors with high initial NO
Authors: Peng Zhe , Jimenez Jose L. 
Published: October 2017

Abstract. Oxidation flow reactors (OFRs) are increasingly employed in atmospheric chemistry research because of their high efficiency of OH radical production from low-pressure Hg lamp emissions at both 185 and 254 nm (OFR185) or 254 nm only (OFR254). OFRs have been thought to be limited to studying low-NO chemistry (in which peroxy radicals (RO2) react preferentially with HO2) because NO is very rapidly oxidized by the high concentrations of O3, HO2, and OH in OFRs. However, many groups are performing experiments by aging combustion exhaust with high NO levels or adding NO in the hopes of simulating high-NO chemistry (in which RO2 + NO dominates). This work systematically explores the chemistry in OFRs with high initial NO. Using box modeling, we investigate the interconversion of N-containing species and the uncertainties due to kinetic parameters. Simple initial injection of NO in OFR185 can result in more RO2 reacted with NO than with HO2 and minor non-tropospheric photolysis, but only under a very narrow set of conditions (high water mixing ratio, low UV intensity, low external OH reactivity (OHRext), and initial NO concentration (NOin) of tens to hundreds of ppb) that account for a very small fraction of the input parameter space. These conditions are generally far away from experimental conditions of published OFR studies with high initial NO. In particular, studies of aerosol formation from vehicle emissions in OFRs often used OHRext and NOin several orders of magnitude higher. Due to extremely high OHRext and NOin, some studies may have resulted in substantial non-tropospheric photolysis, strong delay to RO2 chemistry due to peroxynitrate formation, VOC reactions with NO3 dominating over those with OH, and faster reactions of OH–aromatic adducts with NO2 than those with O2, all of which are irrelevant to ambient VOC photooxidation chemistry. Some of the negative effects are the worst for alkene and aromatic precursors. To avoid undesired chemistry, vehicle emissions generally need to be diluted by a factor of > 100 before being injected into an OFR. However, sufficiently diluted vehicle emissions generally do not lead to high-NO chemistry in OFRs but are rather dominated by the low-NO RO2 + HO2 pathway. To ensure high-NO conditions without substantial atmospherically irrelevant chemistry in a more controlled fashion, new techniques are needed.
Using snowflake surface-area-to-volume ratio to model and interpret snowfall triple-frequency radar signatures
Authors: Gergely Mathias , Cooper Steven J. , Garrett Timothy J. 
Published: October 2017

Abstract. The snowflake microstructure determines the microwave scattering properties of individual snowflakes and has a strong impact on snowfall radar signatures. In this study, individual snowflakes are represented by collections of randomly distributed ice spheres where the size and number of the constituent ice spheres are specified by the snowflake mass and surface-area-to-volume ratio (SAV) and the bounding volume of each ice sphere collection is given by the snowflake maximum dimension. Radar backscatter cross sections for the ice sphere collections are calculated at X-, Ku-, Ka-, and W-band frequencies and then used to model triple-frequency radar signatures for exponential snowflake size distributions (SSDs). Additionally, snowflake complexity values obtained from high-resolution multi-view snowflake images are used as an indicator of snowflake SAV to derive snowfall triple-frequency radar signatures. The modeled snowfall triple-frequency radar signatures cover a wide range of triple-frequency signatures that were previously determined from radar reflectivity measurements and illustrate characteristic differences related to snow type, quantified through snowflake SAV, and snowflake size. The results show high sensitivity to snowflake SAV and SSD maximum size but are generally less affected by uncertainties in the parameterization of snowflake mass, indicating the importance of snowflake SAV for the interpretation of snowfall triple-frequency radar signatures.
GPU-accelerated atmospheric chemical kinetics in the ECHAM/MESSy (EMAC) Earth system model (version 2.52)
Authors: Alvanos Michail , Christoudias Theodoros 
Published: October 2017

Abstract. This paper presents an application of GPU accelerators in Earth system modeling. We focus on atmospheric chemical kinetics, one of the most computationally intensive tasks in climate–chemistry model simulations. We developed a software package that automatically generates CUDA kernels to numerically integrate atmospheric chemical kinetics in the global climate model ECHAM/MESSy Atmospheric Chemistry (EMAC), used to study climate change and air quality scenarios. A source-to-source compiler outputs a CUDA-compatible kernel by parsing the FORTRAN code generated by the Kinetic PreProcessor (KPP) general analysis tool. All Rosenbrock methods that are available in the KPP numerical library are supported.Performance evaluation, using Fermi and Pascal CUDA-enabled GPU accelerators, shows achieved speed-ups of 4. 5 ×  and 20. 4 × , respectively, of the kernel execution time. A node-to-node real-world production performance comparison shows a 1. 75 ×  speed-up over the non-accelerated application using the KPP three-stage Rosenbrock solver. We provide a detailed description of the code optimizations used to improve the performance including memory optimizations, control code simplification, and reduction of idle time. The accuracy and correctness of the accelerated implementation are evaluated by comparing to the CPU-only code of the application. The median relative difference is found to be less than 0.000000001 % when comparing the output of the accelerated kernel the CPU-only code.The approach followed, including the computational workload division, and the developed GPU solver code can potentially be used as the basis for hardware acceleration of numerous geoscientific models that rely on KPP for atmospheric chemical kinetics applications.
Atmospheric inverse modeling via sparse reconstruction
Authors: Hase Nils , Miller Scot M. , Maaß Peter , Notholt Justus , Palm Mathias , Warneke Thorsten 
Published: October 2017

Abstract. Many applications in atmospheric science involve ill-posed inverse problems. A crucial component of many inverse problems is the proper formulation of a priori knowledge about the unknown parameters. In most cases, this knowledge is expressed as a Gaussian prior. This formulation often performs well at capturing smoothed, large-scale processes but is often ill equipped to capture localized structures like large point sources or localized hot spots. Over the last decade, scientists from a diverse array of applied mathematics and engineering fields have developed sparse reconstruction techniques to identify localized structures. In this study, we present a new regularization approach for ill-posed inverse problems in atmospheric science. It is based on Tikhonov regularization with sparsity constraint and allows bounds on the parameters. We enforce sparsity using a dictionary representation system. We analyze its performance in an atmospheric inverse modeling scenario by estimating anthropogenic US methane (CH4) emissions from simulated atmospheric measurements. Different measures indicate that our sparse reconstruction approach is better able to capture large point sources or localized hot spots than other methods commonly used in atmospheric inversions. It captures the overall signal equally well but adds details on the grid scale. This feature can be of value for any inverse problem with point or spatially discrete sources. We show an example for source estimation of synthetic methane emissions from the Barnett shale formation.
Behavioral genetics and thumb sucking in adolescents
Authors: Hatala Jessica 
Published: October 2017

Thumb sucking is a common habit developed by children and begins as early as in utero. However, it becomes problematic when a child continues to suck their thumb past the age of 4 years, when their secondary dentition is developing and preparing to erupt. Prolonged thumb sucking into adolescence can have deleterious effects on dental and skeletal structures based on the duration and how frequent the child engages in this nonnutritive sucking habit. Thumb sucking can lead to various types of effects such as increased overjet, anterior open bite, posterior cross bite, maxillary arch constriction, high palatal vault, and Class II malocclusion. This paper presents a case study, which focuses on chronic thumb sucking in a family, the dental and skeletal changes that the family members experienced, and whether or not this prolonged behavior can be genetically influenced. Based on this case study and the field of behavioral genetics it is possible that there can be a genetic component to the duration of thumb sucking into adolescence.
EDUCAÇÃO FÍSICA E SEMINÁRIOS INTEGRADOS NO ENSINO MÉDIO POLITÉCNICO DO ESTADO DO RIO GRANDE DO SUL
Authors: Silva Lisandra Oliveira , Müller Éder José , Neto Vicente Molina 
Published: October 2017

Objetiva compreender como a Educação Física (EF) no Ensino Médio (EM) Politécnico do Estado do RS está sendo desenvolvida nas escolas e de que maneira é contemplada nos Seminários Integrados (SI) a partir de uma nova Proposta Pedagógica. Realizamos um Estudo de Caso em uma escola estadual durante 10 meses. Os resultados foram organizados em três categorias analíticas e indicam a existência de uma real necessidade de compreensão da Proposta por parte do corpo docente e a utilização da Pesquisa enquanto princípio pedagógico nos SI e nas aulas de EF.
Strange Stage Fellows? Arthur Miller and Harold Pinter
Authors: Greenfield Thomas A. , Carlo Erin M. 
Published: October 2017

Abstract
The body of critical literature concerned with direct comparison between the drama of Arthur Miller and Harold Pinter divides into two contradictory threads. The older, larger thread sees the work of Miller and Pinter as stylistic and intellectual antonyms for one another, an argument grounded in Pinter's early identification with Esslin's The Theatre of the Absurd (1961) and Absurdism's rejection of the kind of dramatic realism and linguistic coherence associated with Miller's best-known works. More recently a small number of critics have introduced a counter thread of interpretations, exploring the means by which Miller and Pinter represent in selected plays similar political, historical, or sociological ideas. This essay takes inspiration from this later thread, presenting a comparison of similarities between Death of a Salesman's Willy Loman and The Homecoming's Max. The article specifically addresses Willy and Max's self-conferral of a bogus ancestral patriarchic authority over their respective households—an authority that is entirely at odds with the actual conditions of their lives.
Estética, historicismo y praxis política: Gramsci y el arte
Authors: Alfaro Salvador Orlando 
Published: October 2017

The critical refections made by Antonio Gramsci on the feld of aesthetics consitute an important source for the study and interpretation of Art from a militant position of historical materialism. The central problem of Gramsci’s aesthetic theory is linked to his notion of historicity and of the relative autonomy of art. Inspite of its determination by culture, society and history, art is characterized by a “concrete historicity”. The degree of complexity of Gramsci’s approach, the relationship between aesthetic and political critique, and popular art and social transformation are the main themes with which the following discussion deals.Realidad: Revista de Ciencias Sociales y Humanidades No. 148, 2016: 81-96
De exceptio plurium litis consortium in erfrechtelijke procedures
Authors: Lavrijssen N. 
Published: October 2017

De exceptio plurium litis consortium in erfrechtelijke procedures
Op 10 maart 2017 heeft de Hoge Raad een arrest gewezen, naar aanleiding waarvan het maar de vraag is of de exceptio plurium litis consortium in de toekomst nog wel met succes kan worden ingeroepen in een dagvaardingsprocedure wanneer er sprake is van een processueel ondeelbare rechtsverhouding. Aan het arrest liggen twee redenen ten grondslag: een doelmatige rechtspleging en overeenstemming met de verzoekschriftprocedure. In deze bijdrage wordt aan de hand van de KEI-wetgeving gezocht naar een mogelijke verklaring voor deze koerswijziging van de Hoge Raad. De auteur vindt een mogelijke verklaring in de toekomstige invoering van één uniforme procedure, ingeleid door een procesinleiding.
A linguagem publicitária na sustentabilidade ambiental
Authors: Almeida Giovana Goretti Feijó de 
Published: October 2017

O objetivo é o de discutir sobre o uso da linguagem publicitária, na perspectiva da sustentabilidade ambiental, colocando a publicidade como prática e como produto que põe em circulação múltiplos significados. Foram analisados anúncios publicitários que utilizam a sustentabilidade ambiental em seus conteúdos como argumento publicitário. Os resultados apontam para a importância da responsabilidade das empresas em fazerem ações publicitárias.Palavras-chave: Publicidade. Discurso publicitário. Sustentabilidade Ambiental.Publicidad de idiomas en la sostenibilidad ambientalResumen: El objetivo es discutir el uso de lenguaje publicitario desde el punto de vista de la sostenibilidad ambiental, la colocación de la publicidad como práctica y como un producto que pone en circulación múltiples significados. anuncios fueron analizados utilizando la sostenibilidad del medio ambiente en su contenido como argumento publicitario. Los resultados apuntan a la importancia de la responsabilidad corporativa en la toma de acciones publicitarias.Palabras clave: Publicidad. Discursos publicidad. Sostenibilidad ambiental.Language advertising in the environmental sustainbilityAbstract: The goal is to discuss the use of advertising language from the perspective of environmental sustainability, placing advertising as a practice and as a product that puts into circulation multiple meanings. advertisements were analyzed using environmental sustainability in their content as an advertising argument. The results point to the importance of corporate responsibility in making advertising actions.Keywords: Advertising. Speeches advertising. Environmental sustainability.