bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary wound closure of diabetic foot ulcers by debridement and stitching
Authors: Ahmed M.E. , Mohammed M.S. , Mahadi S.I. 
Published: November 2016

Objective: The role of stitching in healing diabetic foot ulcers (DFUs) has little attention, with few reports published on the technique. This study aimed to report on the role of stitching in healing of neuropathic DFUs. Method: This comparative study was between patients with diabetes with neuropathic foot ulcers who had undergone wound stitching and those on conventional wound care. The study was carried in Jabir Abu Eliz Diabetic Center Khartoum (JADC) during between January 1 2011 and January 1 2013. All patients presented with neuropathic diabetic septic foot on the plantar aspect or extending up the leg were included. Initial surgical sharp debridement under intravenous broad spectrum antibiotics was performed and oral antibiotics were given 3 days later after the results of the bacterial culture were received. Regular wound debridement was performed with the aim of pairing the wound edges for stitching. Primary closure was performed when the wound was clean from any necrotic tissues and partial closure when the wound was still oozy to secure drainage and avoid splaying of the wound edges. All patients were using either crutches or wheel chair initially until any sepsis cleared and then proper off-loading by shoes purpose made in our centre. Results: A 160 patients with neuropathic DFUs that needed debridement and frequent dressing changes as outpatients were included. Both groups had the same tap water wound dressing either daily, every other day or every two days according to the wound progress. Absorbent dressings and negative pressure wound therapy (NPWT) were unavailable. Half of the patients (n=80) had debridement, frequent dressing change using tap water throughout the period of study (group 1) while the rest (n=80) in addition to wound debridement underwent stitching of their wounds (group 2). Complete healing was achieved in 46 patients in Group 1 (57.5%) compared with 19 patients (23%) in group 2 (p=0.001). The average number of dressings used was 19 in stitch group compared with 30 in the non-stitch group (p=0.000). The average duration of healing in stitch group was 2.9 months compared with 5.7 months in non-stitch group (p=0.000). Conclusion: Stitching of neuropathic DFUs reduced the duration of wound healing and the frequency of wound dressing change.
Evaluation of the assessment and documentation of chronic wounds in residential social care in the Czech Republic
Authors: Saibertová S. , Pokorná A. 
Published: November 2016

Objective: Accurate evaluation of non-healing, chronic wounds followed by the selection of an appropriate therapeutic strategy is a must for the foundation of health-care management. Assessment of non-healing chronic wounds in clinical practice in the Czech Republic is not standardised in acute care settings or in residential social care facilities. The aim of the study was to analyse the methods being used to assess non-healing, chronic wounds in residential social services in the Czech Republic, where more patients with chronic wounds are present because of the increasing incidence of wounds in old age. Method: The research was carried out at 66 residential social care institutions across all regions of the Czech Republic. A mixed model was used for the research (participatory observation including creation of field notes and content analysis of documents for documentation and analysis of qualitative and quantitative data). The same methodology was used in previous work which has been done in acute care settings in 2013. Results: The results of this research have corroborated the inconsistencies in procedures used by general nurses for assessment of non-healing, chronic wounds. However, the situation was found to be more positive with regard to the evaluation of basic/fundamental parameters of a wound (e.g. size, depth and location of the wound) compared with the evaluation of more specific parameters (e.g. exudate or signs of infection). This included not only the number of observed variables, but also the action taken. Both were improved when a consultant for wound healing was present. Conclusion: An effective strategy for wound management depends on the method and scope of the assessment of non-healing, chronic wounds in place in clinical practice in observed facilities; improvement may be expected following the general introduction of ‘non-healing, chronic wound assessment’ algorithm.
Evaluating a native collagen matrix dressing in the treatment of chronic wounds of different aetiologies: a case series
Authors: Ricci E. , Cutting K.F. 
Published: November 2016

Objective: To collate clinical evidence on the use of a native collagen matrix dressing, consisting of a fibrillary collagen network, in patients with a variety of chronic wounds. Method: Patients whose wounds had not improved in the eight weeks before the beginning of the evalutaion were recruited. All participants had their dressings changed twice weekly and received standard adjunctive wound care as part of their treatment. Data, collected over a 4-week period, included: patient demographics, wound surface area measurements, Bates-Jensen score, level of wound pain, wound infection status, wound bed preparation staging score, depth of wound according to tissue type, and photographic imaging of patients' wounds. Results: We recruited 19 patients with 20 wounds and a mean wound duration of 66.6 months (range: 4–480 months). There was a mean decrease in wound surface area of 29% (median reduction: 47%). A reduction in the Bates-Jensen score was demonstrated in 85% of cases. Wound pain reduced by 66.66% and the wound bed preparation score reduced in 16 wounds with four remaining static. No adverse events arose. Conclusion: This case series provides clinical evidence on the use of a native collagen matrix dressing in the management of hard-to-heal wounds that have previously received local standard therapy. The decrease in wound surface area together with other data indicating improved wound status suggests that a native collagen matrix dressing supports healing and improves quality of life through reduction in wound pain.
High-Sensitivity Troponin I in Stable Patients with Atherosclerotic Disease in the TRA 2°P - TIMI 50 Trial
Authors: Eisen Alon , Bonaca Marc P , Jarolim Petr , Scirica Benjamin M , White Harvey D , Tendera Michal , Dellborg Mikael , Nicolau Jose C , Morais Joao , Fox Keith A A , Bohula Erin A , Murphy Sabina A , Braunwald Eugene , Morrow David A 
Published: November 2016

Abstract

BACKGROUND
Cardiac troponin I, measured with a high-sensitivity assay (hs-TnI), is well-established for risk prediction in acute coronary syndromes. However, its prognostic role in stable atherosclerotic disease, particularly for future myocardial infarction (MI), is less well defined.

METHODS
We measured hs-TnI (Abbott ARCHITECT) in 15833 patients with prior MI, ischemic stroke, or peripheral arterial disease from the placebo-controlled Thrombin Receptor Antagonist in Secondary Prevention of Atherothrombotic Ischemic Events (TRA 2°P)–Thrombolysis in Myocardial Infarction (TIMI) 50 trial of the platelet inhibitor vorapaxar, excluding patients with recent MI (&lt;30 days). hs-TnI was categorized into 5 groups based on the detection limit (1.9 ng/L), 99th percentile reference limit (26 ng/L), and tertiles in between (1.9–26 ng/L), as well as sex-specific reference limits.

RESULTS
Higher hs-TnI concentration was associated with older age, male sex, and increased atherosclerosis burden. hs-TnI identified a graded 3-year risk of cardiovascular death, MI, or stroke from 5.0% to 18.6% (P &lt; 0.001), driven by cardiovascular death and MI (P &lt; 0.001). This risk was independent of established clinical risk indicators, B-type natriuretic peptide and C-reactive protein [adjusted hazard ratio 2.70 (95% CI, 1.96–3.71), P &lt; 0.001 for hs-TnI &gt;26 ng/L vs &lt;1.9 ng/L]. In patients with prior MI, there was a pattern of greater absolute benefit with vorapaxar in patients with an increased hs-TnI (absolute risk difference 1.9% with hs-TnI &gt;26 ng/L vs 0.3% with hs-TnI &lt;1.9 ng/L; P interaction = 0.82).

CONCLUSIONS
In stable patients with established atherosclerosis, hs-TnI concentrations effectively stratified the risk of new or recurrent cardiovascular (CV) events, in particular CV death and MI. High-risk patients with prior MI identified by increased hs-TnI had a substantial absolute improvement in net clinical outcome with vorapaxar.
Electronic Reverse Auctions in Public Construction Procurement – Empirical Evidence from the Czech Republic
Authors: Hanák T. 
Published: November 2016

AbstractElectronic reverse auctions (e-RAs) are considered to be an effective tool for negotiating tender prices and achieving cost savings. Furthermore, if multicritera evaluation is used, it can be expected that e-RAs will also contribute to achieving benefits in other areas, e.g. helping to minimize life-cycle costs. This study aims to analyse the mutual relationships between selected e-RA variables. More specifically, correlation analysis is applied to explore real e-RA data representing public tenders for construction work. This study’s findings reveal that the correlations examined are generally weak or very weak. Furthermore, it has been found that the value of correlation coefficients varies depending on the type of structure, and that public tenders are usually evaluated solely on the basis of the criterion of the lowest bid price. Recommendations for public authorities in using e-RAs in the role of the buyer are also provided at the end of this paper.
Multicriteria Selection of Water Insulation Technology for Foundation Walls in an Existing Building
Authors: Rosłon J. , Seroka M. 
Published: November 2016

AbstractIn the authors’ opinion, the issue of incorrectly functioning water insulation of foundation walls in the existing buildings in Poland is currently rather common. The paper includes a multicriteria analysis aimed at arranging the selected options of the foundation wall vertical water insulation technology in an existing model historic building using the weighted sum, entropy and AHP methods. Each of the studied solutions was evaluated in terms of the following criteria: costs of construction works, time of execution of construction works, popularity of using particular insulation options by other contractors, durability of the executed insulation and the degree of nuisance of the executed works.
Quality of Life of People with Disabilities from Sport Participation Point of View
Authors: Nemček Dagmar 
Published: November 2016

Summary
The aim of the study was to compare the satisfaction with quality of life indicators (QoLI) and quality of life domains (QoLD) scores between people with physical disabilities (PPD) and people who are deaf or hard of hearing (PD/HH) from sport participation point of view. The study included 315 individuals with PPD (n = 150; male = 76) and PD/HH (n = 165; male = 85) divided into two groups of those who are regularly participating in sport and those who are not participating in any sport activity in their leisure. The second part of the Subjective Quality of Life Analysis (S.QUA.L.A.) was used. The Pearson chi-square test was used to determine the differences in 23 QoLI and 5 QoLD between PPD and PD/HH from sport participation point of view and student’s two-sample t-test was used to compare overall quality of life (QoL). We found that PD/HH who are participating regularly in sport presented significantly higher satisfaction with 7 evaluated QoLI and with all 5 QoLD. Overall QoL score was significantly higher (p < .01) in PD/HH. In the group of people who are not participating in sport we found significantly higher satisfaction with 13 QoLI in PD/HH and with 8 QoLI in PPD. Satisfaction with 4 QoLD was significantly higher in PD/HH and only with domain (physical health) were significantly higher satisfied PPD (p < .01). Overall QoL score did not show significant differences between groups of people with disabilities who are not participating in any sport. The results of our study confirmed that PD/HH have significantly higher QoL comparing PPD no matter if they participating in sport or not. This evaluation measured by S.QUA.L.A shows that it is a suitable tool to asses QoL in people with different kinds of disabilities.
p-Laplacian Equations in ℝ
N
with Finite Potential via the Truncation Method
Authors: Liu Xiangqing , Zhao Junfang 
Published: November 2016

Abstract
We consider the problem

-

Δ
p

⁢
u

+

a
⁢

(
x
)

⁢

|
u
|

p
-
2

⁢
u

=

|
u
|

q
-
2

⁢
u

{-\Delta_{p}u+a(x)\lvert u\rvert^{p-2}u=\lvert u\rvert^{q-2}u}

in

ℝ
N

{\mathbb{R}^{N}}

, where

1
<
p
<
N

{1<p<N}

,

p
<
q
<

p
*

=

N
⁢
p

N
-
p

{p<q<p^{*}=\frac{Np}{N-p}}

,

Δ
p

{\Delta_{p}}

is the p-Laplacian operator, and the potential function a is positive, bounded and verifies suitable decay assumptions. The existence of infinitely many solutions of the equation is proved via the truncation method.
Microbial nitrogen production, nitrogen balance and excretion of urinary purine derivatives in Corriedale ewes under water deprivation
Authors: Nejad Jalil Ghassemi , Oskouian Ehsan , Kim Byong-Wan , Lee Bae-Hun , Sung Kyung-Il 
Published: November 2016

Abstract
The objective of this study was to determine microbial N production, and urinary excretion of PDs in Corriedale ewes under water deprivation. Nine Corriedale ewes (average BW=45±4.5 kg) were individually fed diets based on maintenance requirements in metabolic crates. Ewes were assigned to three treatment groups according to a 3×3 Latin square design for 3 periods of 21 days duration. The treatments were free access to water (FAW ), 2h water deprivation (2hWD), and 3h water deprivation (3hWD) following feeding. Daily water intake decreased linearly as water deprivation time following feeding increased. Feed intake and fecal excretion were not different among the treatment groups. Urine weight and volume were higher in FAW than water deprived groups. Nitrogen balance including urinary N, retained N, urinary N/intake N, and retained N/intake N were lower in FAW group than other treatment groups, whereas no differences were observed in intake N, fecal N, digestible N, and fecal N/intake N among the treatment groups. Allantoin concentration tended to be higher in FAW group than 2hWD and 3hWD groups while no differences were observed in uric acid, xanthine+hypoxanthine and creatinine concentrations. Microbial N production per DOMR was higher in 2hWD and 3hWD groups than FAW group whereas no differences were observed between 2hWD and 3hWD groups. Index of PDC decreased linearly with water deprivation. It is concluded that water deprivation following feeding, especially 2 h water deprivation in ewes improved microbial N production.
Die Normativität des Krankheitsbegriffs: Zur Genese und Geltung von Kriterien der Krankhaftigkeit
Authors: Hucklenbroich Peter 
Published: November 2016

Zusammenfassung
The question whether the concept of disease is descriptive or normative, is controversial in philosophical debates. A philosophical investigation of medical pathology concerning this question has hitherto been lacking. This paper is based on the reconstruction of general medical pathology as outlined in earlier work of this author. Key concepts of medical pathology are: disease entity, pathologicity, disease criterion, disease value, medical indication. The criteria of pathologicity and the general pathology are briefly sketched. It is shown that these conceptions constitute a dimension of objective value that is rooted in the psychosomatic human nature but is compatible with additional, superposed subjective or sociocultural values concerning disease. The concept and procedure of medical indication constitute the bridge between objective disease values and subjective values or norms. In deciding whether treatment is needed and demanded, the values of the ill subject are decisive. Thus, the controversy between naturalists and normativist may be transformed into a coalition.
Reflective Equilibria in Metrology?
Authors: Schlaudt Oliver 
Published: November 2016

Abstract
In this paper I propose to read the history of systems of units, and in particular the current reform of the International System of Units (SI), understood as a set of measuring norms, in the light of reflective equilibria. The idea is that the model of reflective equilibria actually applies to processes which can be empirically observed or studied. This can help us to understand the nature of normativity and to shed light on its relativity to, and dependence on, practice.
Uncoupling of cardiac and respiratory rhythm in atrial fibrillation
Authors: Platiša Mirjana M. , Bojić Tijana , Pavlović Siniša U. , Radovanović Nikola N. , Kalauzi Aleksandar 
Published: November 2016

AbstractRearranged origin of heart rhythm in patients with atrial fibrillation (AF) influences the regulation of the heart and consequently the respiratory rhythm, and the bidirectional interaction of these rhythms not documented. Hence, we examined coupling of the RR interval and the respiration (Resp) signal by coherence, Granger causality and the cross-sample entropy method of time series analysis in patients with AF and a healthy control group. In healthy subjects, the influence of respiration on cardiac rhythm was found as increased coherence at the breathing frequency (BF) range, significantly stronger interaction and synchrony from Resp to RR than from RR to Resp. On the contrary, in patients with AF, coherence at BF diminished, there were no causal interactions between signals in both directions, which resulted in equally great asynchrony between them. In AF, the absence of full functionality of the sinoatrial node, as an integrator of neural cardiac control, resulted in diminished vagal modulation of heart periods and consequently impaired bidirectional cardio-respiratory interaction.
Remarks on Hodge numbers and invariant
complex structures of compact nilmanifolds
Authors: Yamada Takumi 
Published: November 2016

Abstract
If N is a simply connected real nilpotent Lie group with a Γ-rational complex structure, where Γ is a lattice in N, then
for each s, t.We study relations between invariant complex structures
and Hodge numbers of compact nilmanifolds from a viewpoint of Lie algberas.
Geological model of Lobodice underground gas storage facility based on 3D seismic interpretation
Authors: Kopal Lukáš , Čížek Pavel , Milička Ján 
Published: November 2016

Abstract
The Lobodice underground gas storage (UGS) is developed in a natural aquifer reservoir located in the Central Moravian part of the Carpathian Foredeep in the Czech Republic. In order to learn more about the UGS geological structure a 3D seismic survey was performed in 2009. The reservoir is rather shallow, 400–500 m below the surface. This article describes the process workflow from the 3D seismic field data acquisition to the creation of the geological model. The outcomes of this workflow define the geometry of the UGS reservoir, its tectonics and the sealing features of the structure. Better geological knowledge of the reservoir will reduce the risks involved in the localization of new wells for increasing UGS withdrawal rates.
Genus of abstract modular curves with level-ℓ structures
Authors: Cadoret Anna , Tamagawa Akio 
Published: November 2016

Abstract
We prove – in arbitrary characteristic – that the genus of abstract modular curves associated to bounded families of continuous geometrically perfect

𝔽
ℓ

{\mathbb{F}_{\ell}}

-linear representations of étale fundamental groups of curves goes to infinity with

ℓ

{\ell}

. This applies to the variation of the Galois image on étale cohomology groups with coefficients in

𝔽
ℓ

{\mathbb{F}_{\ell}}

in 1-dimensional families of smooth proper schemes or, under certain assumptions, to specialization of first Galois cohomology groups.
Biomarker strategies: the diagnostic and management process of patients with suspected AMI
Authors: Möckel Martin , Slagman Anna , Searle Julia 
Published: November 2016

Abstract
Security standards of our times largely exclude a discharge of patients with chest pain from the emergency departments (EDs) based on clinical assessment alone. Given the increasing use and consequently crowding of EDs worldwide and the large proportion of patients who present to the EDs with, however vague, signs and symptoms of acute coronary syndrome, there is a strong clinical and public health need to achieve a faster but safe rule-in and rule-out of acute myocardial infarction (AMI) to direct patients onto the correct management pathway. A number of approaches for a faster rule-in and rule-out of AMI are currently under research and evaluation and some have already been integrated into current guidelines and/or implemented into the clinical routine in selected centers. This article summarizes these different diagnostic strategies for patients with suspected AMI, using cardiac troponin alone or in combination with copeptin.
The City through the Eyes of Expressionism
Authors: Demčišák Ján 
Published: November 2016

Abstract
The process of industrialization and urban growth and the development of cities in the first three decades of the 20th century are inevitably related to rapid social changes. The new attitude to life, which corresponds to this process, affected the aesthetic perception and the work of artists as well. The study shows the sensitiveness of German expressionism to the dynamics, drive and chaos of the new city life. The expressionistic picture of the city is clearly ambivalent; it oscillates between fascination on the one hand and antipathy on the other. Expressionism also reflects the social alienation and the feeling of being lonely in a crowd as new phenomena of the 20th century.
Forcing variables in simulation of transpiration of water stressed plants determined by principal component analysis
Authors: Durigon Angelica , Lier Quirijn de Jong van , Metselaar Klaas 
Published: November 2016

AbstractTo date, measuring plant transpiration at canopy scale is laborious and its estimation by numerical modelling can be used to assess high time frequency data. When using the model by Jacobs (1994) to simulate transpiration of water stressed plants it needs to be reparametrized. We compare the importance of model variables affecting simulated transpiration of water stressed plants. A systematic literature review was performed to recover existing parameterizations to be tested in the model. Data from a field experiment with common bean under full and deficit irrigation were used to correlate estimations to forcing variables applying principal component analysis. New parameterizations resulted in a moderate reduction of prediction errors and in an increase in model performance. Agsmodel was sensitive to changes in the mesophyll conductance and leaf angle distribution parameterizations, allowing model improvement. Simulated transpiration could be separated in temporal components. Daily, afternoon depression and long-term components for the fully irrigated treatment were more related to atmospheric forcing variables (specific humidity deficit between stomata and air, relative air humidity and canopy temperature). Daily and afternoon depression components for the deficit-irrigated treatment were related to both atmospheric and soil dryness, and long-term component was related to soil dryness.