bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significant reduction in full‐thickness pressure injuries through the quality improvement project that implements alternating pressure air mattresses
Authors: Chang Hui‐Hsiu , Chiang Wen‐Chu , Hsieh Chia‐Chin , Chang Chen‐Shu , Liao Hui‐Chun , Torng Chau‐Chen , Ma Matthew Huei‐Ming 
Published: October 2024

AbstractTo assess a quality improvement project using alternating pressure air mattresses' impact on reducing full‐thickness pressure injuries by enhancing setting accuracy and device utilization. We retrospectively evaluated adult acute care unit patients with inclusion criteria (Braden scores ≤12 or existing full‐thickness pressure injuries) between May 2020 and August 2023. A wound team attempted to enhance the accuracy, utilization and effectiveness of alternating pressure air mattress implementation. The implementation outcomes were setting accuracy and accurate utilization rates. The clinical outcome was the full‐thickness pressure injury proportion. Utilization and allocation gaps were also calculated. The setting accuracy and accurate utilization rates increased (0.59 to 0.88 and 0.15 to 0.37, respectively). The full‐thickness pressure injury proportion decreased (0.17 to 0.06), with a strong negative correlation coefficient (−0.789) (p < 0.001) with accurate utilization rates. The full‐thickness pressure injury proportion declined faster during the project's complete phase than the partial phase (−0.0046 vs. −0.0016; p < 0.05). The utilization gap narrowed (99 to 60); however, the allocation gap increased (1 to 13), suggesting increased alternating pressure air mattress usage among ineligible patients. Targeting high‐risk patients for alternating pressure air mattress utilization and ensuring correct settings, both performed by a dedicated team, substantially reduces the full‐thickness pressure injury incidence.
Artificial intelligence's suggestions for level of amputation in diabetic foot ulcers are highly correlated with those of clinicians, only with exception of hindfoot amputations
Authors: Mert Merve , Vahabi Arman , Daştan Ali Engin , Kuyucu Abdussamet , Ünal Yunus Can , Tezgel Okan , Öztürk Anıl Murat , Taşbakan Meltem , Aktuğlu Kemal 
Published: October 2024

AbstractDiabetic foot ulcers (DFUs) are a growing public health problem, paralleling the increasing incidence of diabetes. While prevention is most effective treatment for DFUs, challenge remains on selecting the optimal treatment in cases with DFUs. Health sciences have greatly benefited from the integration of artificial intelligence (AI) applications across various fields. Regarding amputations in DFUs, both literature and clinical practice have mainly focused on strategies to prevent amputation and identify avoidable risk factor. However, there are very limited data on assistive parameters/tools that can be used to determine the level of amputation. This study investigated how well ChatGPT, with its lately released version 4o, matches the amputation level selection of an experienced team in this field. For this purpose, clinical photographs from patients who underwent amputations due to diabetic foot ulcers between May 2023 and May 2024 were submitted to the ChatGPT‐4o program. The AI was tasked with recommending an appropriate amputation level based on these clinical photographs. Data from a total of 60 patients were analysed, with a median age of 64.5 years (range: 41–91). According to the Wagner Classification, 32 patients (53.3%) had grade 4 ulcers, 16 patients (26.6%) had grade 5 ulcers, 10 patients (16.6%) had grade 3 ulcers and 2 patients (3.3%) had grade 2 ulcers. A one‐to‐one correspondence between the AI tool's recommended amputation level and the level actually performed was observed in 50 out of 60 cases (83.3%). In the remaining 10 cases, discrepancies were noted, with the AI consistently recommending a more proximal level of amputation than what was performed. The inter‐rater agreement analysis between the actual surgeries and the AI tool's recommendations yielded a Cohen's kappa coefficient of 0.808 (SD: 0.055, 95% CI: 0.701–0.916), indicating substantial agreement. Relying solely on clinical photographs, ChatGPT‐4.0 demonstrates decisions that are largely consistent with those of an experienced team in determining the optimal level of amputation for DFUs, with the exception of hindfoot amputations.
Seasonal Influence on 7,12‐Dimethylbenz[a]anthracene‐Induced Mammary Carcinogenesis in Sprague‐Dawley Rats under Controlled Laboratory Conditions
Authors: Löscher Wolfgang , Mevissen Meike , Häuβler Monika 
Published: October 2024

AbstractThere is good evidence in some species, including rats, that circannual rhythms are innate and can occur even under constant environmental conditions. Such circannual rhythms, e.g. in hormone levels and immune system function, may influence tumourigenesis. This prompted us to study 7,12‐dimelhylbenz[a]anthracene(DMBA)‐induced mammary carcinogenesis at different seasons of the year in female Sprague‐Dawley rats under constant environmental conditions (photoperiod, temperature, air humidity, food). DMBA was administered orally at a dose of 5 mg per rat at the first day of the experiment and then at weekly intervals up to a total dose of 20 mg per rat. Rats were palpated once weekly for the presence of mammary tumours. After 13 weeks, they were necropsied for examination of the number and size of mammary tumours. Age‐matched groups of 36‐99 rats were used per experiment. When the experiment was performed twice within 2 years during the same season (spring/summer), tumour incidence (56 and 61%) and tumour burden were almost equal, indicating that data obtained in this way were reproducible. However, the same experiment performed in autumn yielded a significantly lower tumour incidence (34%) and tumour burden. When the experiment was started during winter, tumour incidence was similar to the spring/summer groups, but tumour burden was lower. The data indicate a seasonal variation in the development and growth of DMBA‐induced breast cancer in Sprague‐Dawley rats. One possible explanation for this phenomenon may be the seasonal variation in pineal melatonin production and immune function previously reported in rodents under constant environmental conditions.
Enhanced low‐field energy storage performance in Nd3+‐doped (Bi0.40K0.2Na0.2Sr0.2)TiO3 high‐entropy ceramics
Authors: Lin Jiawei , Liu Tianyu , Meng Dongdong , He Qiang , Ye Wenhui , Ma Jinxu , Chen Kepi 
Published: October 2024

AbstractThe burgeoning requirement for compact electronic devices has intensified research into lead‐free dielectric ceramics that offer superior recoverable energy storage density and efficiency at low electric fields. In this study, we report the synthesis of Nd3+‐doped (Bi0.4K0.2Na0.2Sr0.2)TiO3 perovskite ceramics via the solid‐state reaction technique. The synthesized ceramics adopted a tetragonal crystal structure. As the concentration of Nd3+ ions increased, both the maximum dielectric constant (εm) and its corresponding temperature (Tm) decrease. The incorporation of Nd3+ ions perturbed the long‐range ferroelectric order, leading to diminished maximum polarization (Pm) and remanent polarization (Pr). The ceramics achieved optimal properties with 12 mol% Nd3+ doping, showcasing a significant recoverable energy storage density of 1.50 J/cm3 at a low electric field of 140 kV/cm, along with an exceptional storage efficiency of 94.6%. This research not only highlights a promising candidate for dielectric materials in low electric field applications but also introduces an innovative approach to enhance energy storage performance.
Surface decoration of Nb2O5 hollow fibers by graphene oxide for enhanced photocatalytic degradation of methylene blue
Authors: Ferreira Eduardo de Paulo , Ribeiro Stella Rodrigues Ferreira Lima , Sousa Thiago Sousa e , Cardoso Vicelma Luiz , Reis Miria Hespanhol Miranda 
Published: October 2024

AbstractThis paper describes the fabrication of ceramic Nb2O5 hollow fibers covered by a thin graphene oxide (GO) layer using the vacuum‐assisted dip‐coating process for the efficient photocatalysis degradation of methylene blue (MB) under UVC light irradiation. Pristine and GO‐coated Nb2O5 hollow fibers were evaluated for photocatalytic degradation at different initial dye concentrations and pH values. A photodegradation of 66.4% of the dye molecules was achieved using the pristine Nb2O5 hollow fibers at 57.4 ± 0.1 mg mL1, initial MB concentration of 10 mg L−1, and pH of 11. Under the same experimental conditions, the GO‐coated Nb2O5 hollow fibers degraded 100% of the MB molecules. Additionally, the GO‐coated Nb2O5 hollow fibers were successfully reused for four reaction cycles and exhibited suitable long‐term stability. Thus, the proposed ceramic Nb2O5 hollow fibers with a surface decorated by a GO layer presented suitable characteristics for use as a photocatalyst in MB degradation.
The effect of digital storytelling on nursing students' compliance with isolation precautions and their knowledge levels: A randomized controlled trial
Authors: Bıyık Bayram Sule , Gülnar Emel , Caliskan Nurcan , Torun Kılıç Çiğdem 
Published: October 2024

AbstractBackgroundDigital storytelling is a teaching tool that can help nursing students master the curriculum and improve their skills. This study investigated the effect of digital storytelling on nursing students' knowledge levels and compliance with isolation precautions.MethodologyA pretest‐posttest open‐label randomized controlled trial. This study was conducted in the nursing department of the faculty of health sciences of a university in Türkiye. The sample consisted of 109 fourth‐year nursing students divided into experimental (n = 66) and control (n = 43) groups. Data were collected using a Demographic Characteristics Questionnaire (DCQ), the Isolation Knowledge Test (IKT), the Questionnaire of Students' Opinions on Digital Storytelling (QSODS) and the Scale of Compliance with Isolation Precautions (SCIP). The experimental group participated a digital storytelling activity, whilst the control group received an education based on the curriculum. The data were analysed using the Mann–Whitney U test, the Wilcoxon test, analysis of variance (ANOVA), and the Spearman correlation test.Results and ConclusionsThe experimental group had significantly higher posttest IKT and SCIP scores than the control group (p < 0.05). Both groups had lower IKT and SCIP scores 2 months after the experiment. However, the change was much smaller in the experimental group. Digital storytelling helped the experimental group participants learn about isolation precautions and how to comply with them. Digital storytelling also promotes learning retention. In conclusion, digital tools are effective in distance learning.
Pre‐service teachers' collaborative learning and role‐based drama activity in a virtual reality environment
Authors: Näykki Piia , Pyykkönen Saara , Latva‐aho Jenni , Nousiainen Tuula , Ahlström Emilia , Toivanen Tapio 
Published: October 2024

AbstractBackgroundIn recent years, the use of virtual reality (VR) environments for education has gained interest in research and education. However, little is known about the potential of social VR environments for collaborative learning.ObjectivesThis study explores pre‐service teachers' (PSTs') collaborative learning and role‐based drama activity, focusing on their self‐created fictional avatar characters and their experiences of presence while working on a group‐based virtual drama activity.MethodsPSTs' course on environmental storytelling was used as the context of the study, in which they worked in small groups in a VR environment (AltspaceVR) from the desktop computers due to COVID‐19 restrictions. Qualitative research data were collected via questionnaire (N = 15). The data were analysed using a community of inquiry model to explore the PSTs' experiences of online presence.Results and conclusionThe results showed that the PSTs' experienced creating and acting as virtual characters as meaningful and engaging activities, and elements of presence were manifested in their reflections. Based on this case study, it can be concluded that the interactive virtual drama activity has the potential to foster the experience of presence in online learning.
Efficacy and safety of vancomycin compared with those of alternative treatments for methicillin‐resistant Staphylococcus aureus infections: An umbrella review
Authors: Purja Sujata , Kim Minji , Elghanam Yomna , Shim Hae Jung , Kim Eunyoung 
Published: October 2024

AbstractObjectiveTo summarize the evidence on the efficacy and safety of vancomycin compared with those of alternative treatments in adult patients with methicillin‐resistant Staphylococcus aureus (MRSA) infection.MethodsPubMed, Embase, and Web of Science were searched up to December 15, 2023, for systematic reviews and meta‐analyses comparing vancomycin with alternative MRSA treatments. Primary outcomes included clinical cure and microbiological eradication rates. Organ‐specific safety outcomes were assessed. Summary estimates were recalculated using a random‐effects model. Evidence was graded using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) tool. This study was registered in PROSPERO (CRD42022340359).ResultsThis umbrella review included 19 studies and 71 meta‐analyses (46 efficacy and 25 safety) comparing vancomycin with 10 alternative treatments across different MRSA infection types and populations. GRADE assessment showed that 29.58% of the meta‐analyses were of high quality. Linezolid and daptomycin showed higher efficacy in MRSA‐induced skin and soft tissue infections and pneumonia (moderate evidence quality) and bacteremia (very low evidence quality), respectively, compared with that of vancomycin. Cephalosporins had a higher risk of nausea, whereas linezolid had a higher risk of nausea, diarrhea, and thrombocytopenia than that of vancomycin. Vancomycin posed a higher risk of rash, pruritus, red man syndrome, and nephrotoxicity than that of alternatives.ConclusionsThe quality of evidence supporting the higher efficacy of alternative treatment over vancomycin for MRSA infection was not high. Given varying safety profiles and advancements in therapeutic monitoring, careful consideration of patient‐specific factors and pharmacokinetics is crucial when selecting treatment alternatives to vancomycin.
Refurbishing the marine parasitoid order Pirsoniales with newly (re)described marine and freshwater free‐living predators
Authors: Prokina Kristina I. , Yubuki Naoji , Tikhonenkov Denis V. , Ciobanu Maria Christina , López‐García Purificación , Moreira David 
Published: October 2024

AbstractPirsoniales is a stramenopile order composed of marine parasitoids of diatoms with unique life cycle. Until recently, a single genus, Pirsonia, uniting six species, was known. The recent identification of new free‐living eukaryotrophic Pirsoniales Pirsonia chemainus, Feodosia pseudopoda, and Koktebelia satura changed our understanding of this group as exclusively parasitic. However, their cell ultrastructure and feeding preferences were not fully studied due to the death of the cultures. In this study, we re‐isolated some of these Pirsoniales and established six new strains exhibiting predatory behavior, including a first freshwater representative. This allowed us to describe five new genera and species, as well as to emend the diagnosis of the order Pirsoniales. The 18S rRNA gene phylogenetic analysis revealed the position of new strains within Pirsoniales and their relationships with parasitoid relatives and environmental sequence lineages. Feeding experiments on novel Pirsoniales strains using diverse algal prey showed that they were not able to form trophosomes and auxosomes. The ability of cell aggregation in Pirsoniales was observed for the first time. One of the studied strains contained intracellular gammaproteobacteria distantly related to Coxiella. Ultrastructural analyses revealed a more complex cytoskeleton structure in Pirsoniales than previously thought and supported the monophyly of Bigyromonadea and Pseudofungi.
Is single‐port laparoscopy or vaginal natural orifice transluminal endoscopic surgery the better option for salpingo‐oophorectomy?
Authors: Gülseren Varol , Güngördük Kemal , Uyar Berican Şahin , Özdemir İsa Aykut 
Published: October 2024

AbstractAimTo compare postoperative pain and recovery in patients undergoing oophorectomy with single‐port laparoscopic surgery (SPLS) versus vaginal natural orifice transluminal endoscopic surgery (vNOTES).MethodPatients who underwent salpingo‐oophorectomy with SPLS or vNOTES between 2016 and 2023 were analyzed retrospectively. Oophorectomy was performed based on the presence of an adnexal mass or breast cancer susceptibility gene mutation.ResultsFifty‐two patients underwent oophorectomy with SPLS and 35 underwent vNOTES. Although the mean mass size was slightly larger in the SPLS group than in the vNOTES group (8.0 ± 4.1 vs. 6.8 ± 3.3 cm), the difference was not significant. There was no difference in operating times between SPLS and vNOTES. The mean visual analog scale and faces pain scale scores 2 and 6 h postoperatively were lower in the vNOTES group. The mean quality of recovery‐40 (QoR‐40) score was higher in the vNOTES group (156 ± 14 vs. 148 ± 11; p = 0.009). This analysis identified vNOTES as an independent predictor of a high QoR‐40 score.ConclusionThe vNOTES group experienced less pain during the early postoperative period than the SPLS group. Although the operating and removal times were similar, the port setup time was longer for the vNOTES group.
Is there a mental health wake following the COVID‐19 pandemic on adolescents in a male juvenile prison?
Authors: Fix Rebecca L. , Thompson Kelli R. , Doan Brandon 
Published: October 2024

AbstractLingering effects of the COVID‐19 pandemic loom large in the United States but are particularly of concern in prison settings. In the current study, we examine the ongoing mental health consequences of the pandemic among young people incarcerated in a male juvenile prison. Sequential mixed methods data were obtained—78 young people assigned male at birth completed surveys and 19 completed individual interviews. Seven staff were also interviewed about youth experiences during and following the pandemic. Youth survey results indicated racial and ethnic identity exploration, feeling less safe at night, and experiencing staff harassment were significantly associated with some negative mental health concerns, yet lingering COVID‐19 policies were not. Triangulation with interviews underscored these findings by highlighting more specific concerns related to COVID‐19, such as social isolation, loneliness, and concerns about the indirect effects the pandemic might have on court outcomes and educational goals. Overall, results of the current analysis provide evidence that incarceration continues to be traumatizing and harmful to youth mental health even following the pandemic. To a lesser extent, these results also imply that lingering effects of the pandemic and concurrent cultural and racial tensions have delayed impacts on the mental health of incarcerated youth during this tumultuous time. Taken together, study findings suggests juvenile prisons must implement readiness plans to mitigate these and other harmful effects of juvenile incarceration in the future.
Trends in psychosocial research on LGBTIQ+ populations in Latin America: Findings, challenges, and concerns
Authors: Barrientos Jaime , Nardi Henrique Caetano , Mendoza‐Pérez Juan Carlos , Navarro María Camila , Bahamondes Joaquín , Pecheny Mario , Radi Blas 
Published: October 2024

AbstractPsychosocial research on lesbian, gay, bisexual, transgender, intersex, and queer (LGBTIQ+) populations from Latin America is relatively recent. Initially, research focused mainly on prejudice, using qualitative techniques. Studies on LGBTIQ+ populations, using more sophisticated psychosocial theories such as those of Herek or Meyer, began in the mid‐1990s. This study deals with surveys and scales based on non‐probabilistic samples, LGBTIQ+ populations being the first studied. In the early 2000s, queer and/or LGBTIQ+ theories were introduced, and research has been much more interdisciplinary. This paper describes the theoretical frameworks used in LGBTIQ+ research in Latin America and examines distinctions in the findings from Mexico, Colombia, Chile, Argentina, and Brazil. Future research must involve cross‐cultural studies, systematic or scoping reviews, and studies on non‐binary populations. Finally, the conditions for reimaging LGBTIQ+ research in Latin America are discussed.
A systematic PCR record‐based re‐call of HCV‐RNA‐positive people enables re‐linkage to care and HCV elimination in Austria — The ELIMINATE project
Authors: Balcar Lorenz , Schwarz Michael , Dorn Livia , Jachs Mathias , Hartl Lukas , Weseslindtner Lukas , Pfisterer Nikolaus , Hennlich Barbara , Stückler Annika , Strassl Robert , Voill‐Glaninger Astrid , Hübl Wolfgang , Willheim Martin , Köhrer Karin , Jansen‐Skoupy Sonja , Tomez Sabine , Krugluger Walter , Madl Christian , Burghart Lukas , Antonitsch Lukas , Weidinger Gerhard , Riedl Florian , Laferl Hermann , Hind Julian , Wenisch Christoph , Sebesta Christian , Wachter‐Welzl Julia , Watzl Paul , Neuhauser Magdalena , Chromy David , Mandorfer Mattias , Schmid Daniela , Gschwantler Michael , Reiberger Thomas , Maieron Andreas , Bauer David J.M. , Schwarz Caroline 
Published: October 2024

AbstractBackground and AimsIdentification of people living with hepatitis C virus (HCV) via readily available laboratory records could be a key strategy for macro‐elimination, aligning with the WHO elimination goal. Therefore, the ELIMINATE(ELIMINation of HCV in AusTria East) project aimed to systematically re‐link people with a ‘last‐positive’ HCV‐RNA PCR record to care.MethodsIn 10 major liver centres in Eastern Austria, a systematic readout of ‘last‐positive’ HCV‐RNA PCR test records obtained between 2008 and 2020 were conducted and linked to available patient contact data. Between 2020 and 2023, individuals were contacted first by phone, then by letter, to inform them about the availability of effective direct‐acting antiviral (DAA) treatment and invite them for pre‐treatment evaluation.ResultsThe overall cohort of last‐positive HCV+ individuals included 5695 subjects (62.5% males, mean age 57.3 ± 17.3 years); of note, 1931 (34%) of them had died and 759 (13%) individuals had no valid contact information. Of the remaining 3005 individuals, 1171 (40.0%) had already achieved sustained virological response (SVR) at the time of re‐call. We successfully reached 617 (20.5%), of whom 417 (67.6%) attended their pre‐treatment visit, and 397 (64.3%) commenced DAA‐therapy. HCV cure has been confirmed in 326 individuals, corresponding to an SVR rate of 82.1%.ConclusionThe ELIMINATE project identified 5695 people living with HCV who were ‘lost to care’ despite documented HCV viraemia. While invalid contact data were an evident barrier to HCV elimination, premature deaths among the cohort underscored the severity of untreated HCV. The implementation of a systematic HCV‐RNA PCR recorded‐based re‐call workflow represents an effective strategy supporting the WHO goal of HCV elimination.