bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alloimmunisation in transfused patients: serial cross-matching in a population of hospitalised cats
Authors: Hourani Layla , Weingart Christiane , Kohn Barbara 
Published: January 2017

Objectives Cross-matching is currently recommended as part of pre-transfusion testing for repeat transfusions in cats 4 days after having received an initial transfusion. This prospective study determined when and if cats developed positive cross-match (CM) results after having been transfused with AB-compatible blood. Methods Donors were selected according to standard transfusion safety protocols. Twenty-one hospitalised anaemic recipients (blood type A: n = 20; blood type B: n = 1) received 1–4 (median 2) whole blood transfusions (WBTs) over 1–6 days (median 2) in 33 transfusion instances. The tube CM method, including major, minor and recipient control, was employed. Macroscopic and microscopic agglutination reactions were evaluated according to a predetermined scale. CM tests with a positive recipient control could not be evaluated. Results No signs of an acute transfusion reaction were observed. A total of 63 CMs were performed. In one cat with immune-mediated haemolytic anaemia the CM could not be evaluated (positive recipient control). The minor CM was negative in all cases. Fifteen of 20 cats had a negative major CM (MCM) 1–12 days (median 5) after their first transfusion. A positive MCM was observed in five cases after 2–10 days (median 5) post-first WBT. These five cats had received a total of 1–4 (median 2) WBTs. Cats with a negative MCM had received 1–3 (median 2) WBTs. In 51.5% (17/33) of transfusion instances, the cat’s haematocrit increased as expected, with cats with a positive MCM at 40% (4/10) vs 56.5% (13/23) if MCM was negative. Conclusions and relevance Twenty-five percent (5/20) of the feline recipients likely developed alloantibodies against erythrocyte antigens outside of the AB system as early as 2 days post-first WBT. This adds data to the recommendation to include cross-matching in pre-transfusion screening tests.
A retrospective analysis of a pediatric tele-echocardiography service to treat, triage, and reduce trans-Pacific transport
Authors: Rouse Christopher A , Woods Brandon T , Mahnke C Becket 
Published: January 2017

Introduction Tele-echocardiography can ensure prompt diagnosis and prevent the unnecessary transport of infants without critical congenital heart disease, particularly at isolated locations lacking access to tertiary care medical centers. Methods We retrospectively reviewed all infants who underwent tele-echocardiography at a remote 16-bed level IIIB NICU from June 2005 to March 2014. Tele-echocardiograms were completed by cardiac sonographers in Okinawa, Japan, and transmitted asynchronously for review by pediatric cardiologists in Hawaii. Results During the study period 100 infants received 192 tele-echocardiograms: 46% of infants had tele-echocardiograms completed for suspected patent ductus arteriosus, 28% for suspected congenital heart disease, 12% for possible congenital heart disease in the setting of likely pulmonary hypertension, and 10% for possible congenital heart disease in the setting of other congenital anomalies. Of these, 17 patients were aeromedically evacuated for cardiac reasons; 12 patients were transported to Hawaii, while five patients with complex heart disease were transported directly to the United States mainland for interventional cardiac capabilities not available in Hawaii. Discussion This study demonstrates the use of tele-echocardiography to guide treatment, reduce long and potentially risky trans-Pacific transports, and triage transports to destination centers with the most appropriate cardiac capabilities.
The English Police 1829–1856: Consensus or Conflict?
Authors: Harrison Arch 
Published: January 2017

The focus of this paper is the new English police institution during the formative years of its development from 1829 to 1856. It is based on the notion that historical perspectives are important for contemporary policing because of its recurring penchant to re-visit the past in an attempt to rationalise the present and justify the future. For the purpose of this analysis, this paper takes the two principal historical perspectives — orthodoxy and revisionism — and attempts to identify which of these schools of thought is the most persuasive in explaining the emergence of, opposition to, control of and role of the new police. This approach is an adaptation of the comparative model used by Robert Reiner in ‘The Politics of the Police’ (1992b). It is contended that the analysis is an ‘eclectic perspective’ with the conclusion favouring revisionism. In this sense, the birth of the new police institution in London in 1829 is best explained by orthodoxy, whereas the aspects of opposition, control and role during its development and expansion are weighted in favour of revisionism. It is contended that the analysis is an ‘eclectic perspective’ with the conclusion favouring revisionism. In this sense, the birth of the new police institution in London in 1829 is best explained by orthodoxy, whereas the aspects if opposition, control and role during its development and expansion are weighted in favour of revisionism.
The Effects of Eprosartan on Cytoplasmic Free Calcium Mobilisation, Platelet Activation and Microparticle Formation in Hypertension. Could they be Relevant to Stroke Prevention?
Authors: Martínez Silvestre Marcial 
Published: January 2017

The study examined a number of parameters of platelet function and activation in hypertensive patients compared with normotensive patients. It also examined the effects of the angiotensin receptor blocker eprosartan on these parameters. There were 30 patients with stage 1 or stage 2 hypertension plus 31 well-matched controls in this study. Phosphatidylserine, a measure of circulating activated platelets, was expressed more in hypertensive patients than in controls. Eprosartan partially corrected the enhanced platelet reactivity.There were greater numbers of activated platelet microparticles in hypertensive patients compared to controls. Again, eprosartan reduced this hyperproduction. Calcium kinetics of platelets were measured with flow cytometry using fluorescent markers.The free calcium concentration and its rise in response to thrombin were greater in hypertensive patients. Eprosartan significantly changed these parameters towards control values and reduced platelet activation. patients. Thus, eprosartan has the potential to reduce the risk of atherosclerotic events in hypertensive patients.
Impaired olfactory function is related to the presence of neuropathy in adults with type 1 diabetes
Authors: Duda-Sobczak Anna , Araszkiewicz Aleksandra , Urbas Magdalena , Borucki Lukasz , Kulas Katarzyna , Chudzinski Maciej , Suwalska Aleksandra , Zozulinska-Ziolkiewicz Dorota 
Published: January 2017

Introduction: Olfactory dysfunction is suggested to be a clinical manifestation of central diabetic neuropathy. The aim of the study was to assess olfactory function in adult patients with type 1 diabetes. Materials and methods: A total of 106 patients with type 1 diabetes and 30 healthy subjects were included in the study. We evaluated the metabolic control of diabetes and the presence of chronic complications. Olfactory function was assessed with Sniffin’ Sticks. Results: We found a negative correlation between olfactory identification scores and body mass index ( Rs −0.2; p = 0.04) and triglycerides ( Rs = −0.2; p = 0.04). We showed lower olfactory identification scores in neuropathy group versus non-neuropathy group [8 (interquartile range, 7–9) vs 10 (interquartile range, 9–11) points; p = 0.005]. In multivariate linear regression, impaired olfaction was independently associated with neuropathy (beta, −0.3; p = 0.005). In multivariate logistic regression, diabetes duration (odds ratio, 1.06; 95% confidence interval, 1.00–1.11; p = 0.04) and olfactory identification score (odds ratio, 0.61; 95% confidence interval, 0.43–0.85; p = 0.003) were independently associated with neuropathy. Conclusion: Olfactory dysfunction is observed in patients with type 1 diabetes and diabetic peripheral neuropathy.
A Positive Psychology Theoretical Model to Coach Veterans Through Successful Transitions
Authors: Miller Lisa M. 
Published: January 2017

A conceptual model was constructed on the basis of an extensive literature review examining positive psychology topics as related to human resource development. The Problem Research primarily focused on workplace or university settings. Fostering positive psychology in veterans’ work transitions is a new and an important component to human resource development research. The Solution The benefits of focusing on positive psychology in the military to better prepare veterans for the workforce starts with support from research in the workplace and the university setting. Psychological well-being is vital to workplace performance and engagement. Despite the research supporting positive psychology, systematic approaches to developing psychological well-being often go missing in organizations and in the military. The Stakeholders An institution wide implementation of a positive psychology approach imbedded in human resource development would allow for measurement of the impact in the veteran population. Models of positive psychology training would guide the promotion of well-being in military to work transitions.
Singing by Number in Mid-Nineteenth-Century America
Authors: Hansen Linda 
Published: January 2017

Recognizing the broad potential of singing as a facilitator of moral instruction, academic learning, and societal participation, New Hampshire native Asa Fitz (1810–1878) was committed to advancing music and music education. A prolific publisher, editor, and author, he was involved in the production of dozens of works filled with songs and music, designed to further everything from reform movements to congregational singing, spiritualism to family life. As a singing master and music teacher, he instructed both children and other teachers, promoting his song books, his instructional techniques, his personal principles, and his overriding belief that everyone could, and should, learn to sing. Yet, for all that he was well known during his lifetime, little scholarly attention has been paid to the man, his philosophical underpinnings, or his disparate publications. This article focuses on the development of his “new system of figured music,” culminating with the publication of School Songs for the Million! in 1850. It briefly reviews the concept and expressions of alternate systems of musical notation in early to mid-nineteenth-century America and then places Fitz within that context, as he created, developed, and promoted his system to children and teachers. Though School Songs for the Million! was not as commercially successful as some of his other titles, it serves to demonstrate Fitz’s willingness to experiment with unconventional and controversial ideas in an effort to advance participation in music.
Interventional Therapy for Transplant Renal Artery Stenosis Is Safe and Effective in Preserving Allograft Function and Improving Hypertension
Authors: Wang Lili , Liu Bin , Yan Jieke , Wang Yongzheng , Wang Wujie , Wang Wei , Chang Haiyang , Wang Hongwei , Wang Changjun , Li Zheng , Li Yuliang 
Published: January 2017

Purpose: To evaluate the outcomes of percutaneous intervention (PI) for transplant renal artery stenosis (TRAS). Materials and Methods: Doppler ultrasonography was used as the screening tool, and angiography was the diagnostic method for TRAS. The indications for PI were (1) a reduction in lumen diameter of >50% or (2) a mean pressure gradient of >15 mm Hg. Technical success was assessed immediately after the procedure. The short-term results of stenosis were evaluated by serum creatinine (Scr) levels and blood pressure (BP). The long-term results were assessed by graft survival and renal function. Results: From October 2009 to July 2015, a total of 660 patients had kidney transplantation and 22 cases underwent PI. The technical success was 100%. The mean Scr level preintervention was 321.6 ± 167.2 (range, 171.3-862.0) μmol/L, and it decreased to 145.3 ± 44.7 (range, 74.3-260.8) μmol/L 1 month postintervention ( P < .001). Blood pressure was also improved at 1 month postintervention, as assessed by systolic (157.0 ± 13.0 vs 131.0 ± 11.0 mm Hg, P < .001), diastolic (95.0 ± 5.0 vs 77.0 ± 9.0 mm Hg, P < .001), and mean arterial pressure (116.0 ± 7.0 vs 95.0 ± 9.0 mm Hg, P < .001). The patency rate was 100%, 91.7%, and 85.7% at 1, 3, and 12 months, respectively. The secondary patency rate was 100%. Graft survival was 100% during follow-up. There was no significant deterioration in graft function or BP ( P > .05) postintervention when compared to posttransplantation. Conclusions: Percutaneous intervention for TRAS is safe and results in significant improvement both in allograft function and in BP.
Advanced Chronic Venous Insufficiency
Authors: Dua Anahita , Heller Jennifer A. 
Published: January 2017

Introduction: Intervention for advanced chronic venous insufficiency is considered an appropriate standard of care. However, outcomes vary among patients who present in advanced clinical stages of disease. The main objectives of this study were to determine whether racial disparity exists at initial presentation and response to intervention. Methods: A retrospective database was created to include all radiofrequency ablation procedures performed by a single surgeon from January 14, 2009, through May 25, 2011. Demographics, clinical traits, race, procedure, and outcomes were analyzed. Stepwise model selection reduced candidate baseline factors to a final parsimonious model, which was analyzed using analysis of variance. Results: The database consisted of 300 patients with a predominant female (n = 215, 85%) base and 85 (15%) males, with a mean age distribution of 53 years. The mean body mass index was 30.2. Racial distribution revealed Asian (n = 9, 3.3%), Pacific Islander (n = 1, 0.4%), African American (n = 37, 13.6%), and Caucasian (CAU, n = 225, 82.7%). African Americans presented with more advanced clinical stages than the CAU group—C2: African American 21.6%, CAU 36.7%; C4: African American 35%, CAU 24.3%; and C6: African American 35.1%, CAU 7.5%. African Americans demonstrated a higher preoperative venous clinical severity score (VCSS) than their CAU counterparts. Postprocedural decrease in VCSS score was lower in African Americans than their CAU counterparts. Conclusion: African American patients present with more advanced venous insufficiency than CAUs. Postprocedural analysis reveals not only slower ulcer healing times but also higher ulcer recurrence rates.
One-Year Follow-Up After Hybrid Thoracoabdominal Aortic Repair
Authors: van de Graaf Rob A. , Grüne Frank , Hoeks Sanne E. , ten Raa Sander , Stolker Robert Jan , Verhagen Hence J. M. , van Lier Felix 
Published: January 2017

Background: Compared to open thoracoabdominal aortic aneurysm (TAAA) repair, hybrid repair is thought to be less invasive with better perioperative outcomes. Due to the extent of the operation and long recovery period, studying perioperative results may not be sufficient for evaluation of the true treatment effect. The aim of this study is to evaluate 1-year mortality and morbidity in patients with TAAA undergoing hybrid repair. Methods: In a retrospective cohort study, all medical records of patients undergoing hybrid repair for TAAA at the Erasmus University Medical Center between January 2007 and January 2015 were studied. Primary outcome measures were 30-day and 1-year mortality. Secondary outcome measures included major in-hospital postoperative complications. Results: A total of 15 patients were included. All-cause mortality was 33% (5 of the 15) at 30 days and 60% (9 of the 15) at 1 year. Aneurysm-related mortality was 33% (5 of the 15) and 53% (8 of the 15) at 30-day and 1-year follow-up, respectively, with colon ischemia being the most common cause of death. Major complication rate was high: myocardial infarction in 2 (13%) cases, acute kidney failure in 5 (33%) cases, bowel ischemia in 3 (20%) cases, and spinal cord ischemia in 1 (7%) case. Conclusion: The presumed less invasive nature of hybrid TAAA repair does not seem to result in lower complication rates. The high mortality rate at 30 days continues to rise dramatically thereafter, suggesting that 1-year mortality is a more useful clinical parameter to use in preoperative decision-making for this kind of repair.
MynxGrip for Closure of Antegrade Puncture After Peripheral Interventions With Same-Day Discharge
Authors: Pruski Maciej J. , Blachut Aleksandra M. , Konkolewska Magda , Janas Adam , Hrycek Eugeniusz , Buszman Piotr P. , Kiesz Radoslaw S. 
Published: January 2017

Background: This was the first prospective study to assess the safety and efficiency of MynxGrip vascular closure device (VCD) in peripheral interventions with antegrade access. Methods and Results: We enrolled 66 consecutive patients from 1 center. All patients were discharged home on the day of procedure and were observed for adverse events at 1 and 30 days of follow-up. No major complications were observed. The rate of minor complications (conversion to manual or mechanical compression) was 7.6%. Postdischarge, 3% of patients experienced minor complications—small abscess, ipsilateral deep vein thrombosis. In 1 patient, a second VCD was deployed after device failure. The derived device failure rate was 5.9%. No patients required hospitalization. No late bleeding and no hematomas >6 cm were noted. The mean time to discharge was 4 hours and 5 minutes. Conclusion: The MynxGrip was safe and effective in sealing access sites after antegrade femoral artery puncture with same-day discharge.
Dynamic Hip Screw Fixation versus Multiple Screw Fixation for Intracapsular Hip Fracture
Authors: Jettoo Prithee , James Philip 
Published: January 2017

Purpose To compare dynamic hip screw (DHS) fixation with multiple screw fixation for intracapsular hip fractures in terms of complications and conversion to hemiarthroplasty or total hip arthroplasty (THA). Methods Records of 52 884 patients aged ≥50 years who underwent internal fixation using a dynamic hip screw (n=18 014, 34.1%) or multiple screws (n=34 870, 65.9%) for intracapsular femoral neck fracture from September 2007 to September 2013 were extracted from the hospital admission database that covers all admissions to the National Health Service hospitals in England using the ICD-10 and OPCS-4 codes. Gender, age, and Charlson comorbidity score of each patient were recorded, as were complications at specific time intervals and revision to hemiarthroplasty or THA at one and 4 years. Results Compared with DHS fixation, multiple screw fixation resulted in shorter hospital stay (15 vs. 13 days, p<0.001) and lower rates of 30-day myocardial infarction (2% vs. 1.5%, p=0.022), 30-day lower respiratory tract infection (12.4% vs. 10.6%, p=0.001), 90-day mortality (10.4% vs. 8.6%, p=0.001), and avascular necrosis (0.1% vs. 0.06%, p=0.032), but a higher rate of conversion to hemiarthroplasty or THA at one or 4 years (all p<0.001). Conclusion Multiple screw fixation for intracapsular hip fracture was associated with a higher conversion rate to hemiarthroplasty or THA at one and 4 years, compared with DHS fixation.
Predictors of Mortality in Patients with Femoral Neck Fracture
Authors: Major Lisa J , North John B 
Published: January 2017

Purpose To identify patient and procedural factors associated with in-hospital mortality following a femoral neck fracture. Methods Records of 598 female and 259 male consecutive patients aged 29 to 108 (median, 82) years admitted between 2010 and 2014 with femoral neck fracture were retrospectively reviewed to determine patient and procedural factors associated with in-hospital mortality. Results 73% of patients were operated on within 48 hours of admission. The in-hospital mortality was 7.5%, with 2.1% occurring preoperatively and 5.4% postoperatively. Factors associated with increased preoperative mortality included being non-ambulant prior to admission (p=0.015), residence in interim care (p=0.001) or low-level care (p=0.049), having synchronous fractures (p=0.001), and having a concurrent acute medical condition (p<0.001). Patient factors associated with increased in-hospital mortality included male gender (p=0.041), age >80 years (p=0.001), non-ambulatory status (p=0.015), residence in high-level care (p=0.031) or low-level care (p=0.018), American Society of Anesthesiologists grade 4 or 5 (p<0.001), weekend admission (p<0.001), and having an acute medical condition on admission (p<0.001). Procedural factors associated with increased in-hospital mortality included >96-hour delay to surgery from admission (p<0.001), surgery over the weekend (p=0.005), and surgical interventions other than total hip arthroplasty (p<0.05). Conclusion Identification of patient and procedural factors can guide changes in best practice to decrease mortality following a femoral neck fracture.
Conservative versus Surgical Treatment for Displaced Fracture of the Medial Process of the Calcaneal Tuberosity
Authors: Li Bing , Wu Gen-Bin , Yang Yun-Feng 
Published: January 2017

Purpose To compare the outcome following conservative or surgical treatment for displaced fracture of the medial process of the calcaneal tuberosity. Methods 14 men and 4 women aged 20 to 44 years chose to undergo conservative (9 feet) or surgical (10 feet) treatment by a single surgeon for closed displaced fracture of the medial process of the calcaneal tuberosity. The injury mechanism was a fall from a height of <1.5 m; the mean time from injury to treatment was 3 (range, 1–7) days. Conservative treatment comprised immobilisation in a plaster cast. Surgical treatment involved fixation with a half-thread cannulated screw for large fragments (in 6 feet) or a mini-plate for comminuted fragments (in 4 feet). At the final follow-up, the American Orthopaedic Foot and Ankle Society (AOFAS) ankle and hindfoot score was evaluated. Results The conservative and surgery groups were comparable in terms of age, gender, and fracture displacement. The mean follow-up duration was 20 (range, 14–24) months. All patients had bone union; none had implant loosening or breakage. One patient with surgical treatment developed skin numbness at the medial aspect of the heel that resolved following neurotrophic drug treatment for 3 months. The surgery group achieved earlier full weight-bearing (5.8 vs. 7.5 weeks, p<0.001) and return to work (5.9 vs. 8.2 weeks, p=0.048), but comparable AOFAS score (89.0 vs. 88.2, p=0.4). Conclusion Surgery for displaced fracture of the medial process of the calcaneal tuberosity enabled earlier full weight-bearing and return to work but comparable AOFAS score.