bluuebunny/crossref_metadata_2025_split huggingface dataset:
Linear open circuit voltage‐variable step‐size‐incremental conductance strategy‐based hybrid MPPT controller for remote power applications
Authors: Thangavelu Anuradha , Vairakannu Senthilkumar , Parvathyshankar Deivasundari 
Published: May 2017

This study presents a novel hybrid maximum power point tracking (HMPPT) controller capable of harvesting maximum power from solar panels in a remote power park which can be used for applications such as outdoor uninterruptible power supply, cellular phone and laptop chargers. The proposed HMPPT controller combines two MPPT methods, namely the linear open‐circuit voltage method and variable step‐size incremental conductance method and it has a simple and robust way of tracking MPP based on the relationship between the solar panel characteristics and load line. A 100 W photovoltaic (PV) generation system with soft switched interleaved flyback (SSIFB) converter is built to implement the proposed HMPPT algorithm. The soft switching of flyback converters in the proposed PV‐SSIFB system is achieved by zero voltage switching–pulse width modulation technique. The steady‐state performance under various constant irradiations and transient characteristics for rapidly varying irradiations and load changes are investigated. The effectiveness of the controller in the recommended circuit is verified by the simulation results and validated using a prototype model. Both simulation and experimental results show several advantages, namely accuracy, high tracking speed, minimum power loss and increased adaptability for a wide range of irradiations and load.
Meningioma with Metastatic Malignant Melanoma: An Unusual Coincidence
Authors: Savant H. , Doshi Anand , Sheikh Zafar , Mahajan Vijay 
Published: May 2017

AbstractSimultaneous occurrence of meningioma and brain metastasis as two different histopathologically-proven lesions has been often reported in literature, however, to the best of our knowledge, contiguous occurrence of meningioma and malignant melanoma has not been reported previously in literature. A 50-year-old woman presented with features of raised intracranial pressure and left upper motor neuron signs. Imaging findings were suggestive of right frontoparietal and right parietal extra-axial space occupying extra-axial lesions. Patient underwent right frontotemporoparietal craniotomy with excision of both tumors under general anesthesia. Histopathological analysis was suggestive of transitional meningioma (World Health Organization [WHO] grade I) and malignant melanoma (WHO grade IV). Simultaneous presence of two tumors in the brain might be of the same or different histopathology. In such dual tumors, metastasis cases are varied and one source of it may be melanoma of the skin. Hence, dermatological examination can reveal the primary source of tumor in select cases.
Spontaneous Healing of a Pediatric Scaphoid Proximal Pole Fracture Nonunion
Authors: Riley Nicholas , McNab Ian , Rupani Neal 
Published: May 2017

Background Scaphoid fractures in the pediatric population are rare. The majority of nondisplaced fractures tend to unite; however, there is an increased risk of nonunion in proximal pole fractures. Limited evidence exists in their outcomes, owing to the scarcity of the fracture pattern.
Case Description A 13-year-old boy who presented late after developing a traumatic proximal pole scaphoid fracture developed nonunion. He was treated conservatively owing to it being asymptomatic and developed union at 18 months.
Literature Review No previous case of proximal pole pediatric scaphoid fractures with established nonunion that has developed union with conservative management has been described.
Clinical Relevance The authors highlight a unique case of an established proximal pole scaphoid nonunion in a child progressing to union with nonoperative intervention. Owing to its rarity and difficulty in obtaining research, we recommend consideration of nonoperative management of asymptomatic nondisplaced proximal pole fractures in children.
The Influence of the Type of Surgical Thread and Suture in the Open Carpal Tunnel Syndrome Surgery
Authors: Magalhães Marcelo José Silva , Cruz Beatriz Xavier , Santos Fabrício Conceição dos , Oliveira Isabella Mendes de , Sousa João Pedro Saraiva , Guimarães Thaís de Oliveira , Lopes Thiago Antunes , Hoffmann Ernesto José 
Published: May 2017

AbstractCarpal tunnel syndrome (CTS) is the result of compression and/or traction of the median nerve in the carpal tunnel. It is the most frequent compressive neuropathy of the upper limbs and it is usually idiopathic. Diagnosis is essentially clinical, defined by symptoms and provocative tests. Decompression of the median nerve by section of the transverse carpus ligament is the treatment of choice, but the lack of consensus on the type of suture and surgical thread to be used in the open carpal tunnel decompression surgery justifies the importance of evaluating the comparative results of existing studies, aiming to describe the influence of different types of sutures and surgical threads to guide the professionals about the most appropriate conduct. This is a systematic review of the international and national literature. Four studies comparing the influence of surgical threads and one study evaluating the influence of the type of suture were found. From the comparative studies, it was observed that there is advantage in the use of nonabsorbable suture due to the lower occurrence of inflammation and postoperative wound complications. When using Donatti sutures, wound edge inversion is less likely to occur compared with single individual sutures, but they are also related to longer postoperative pain.
Luminal Obstruction of Double J Stents Due to Encrustation Depends on Indwelling Time: A Pilot Study
Authors: Kadihasanoglu Mustafa , Kilciler Mete , Atahan Ozcan 
Published: May 2017

Abstract
Double J (DJ) stents serve as a therapeutic option to relieve obstruction. However, incrustation can be an important cause of dysfunction of these stents. We investigated the relationship between incrustation of DJ stents and indwelling time using a grading system for luminal occlusion.
The medical records of 42 patients with urolithiasis related to DJ stent incrustation were retrospectively reviewed. All polyurethane DJ stents were examined for severity of incrustation with a grading system based on the occlusion of stent lumen. For the level of grades 3 groups of patients were compared: group 1 included 14 patients whose stents were removed a month after insertion; group 2 included 16 patients whose stents were removed 45 days after insertion; group 3 included 12 patients whose stents were removed 3 months after insertion.
The incrustation of 42 DJ stents was graded from 1 to 3 depending on the occlusion of the DJ stent. Mean age of patients was 39.6±6.71 years and median indwelling time was 50 days. The groups were similar regarding age, sex, and side of DJ stent. In comparison, the grade of incrustation in group 3 was higher than the grades in group 1 and group 2 (p=0.001).
Incrustation is one of the most important complications of DJ stents, and was related to indwelling time. Therefore, close follow-up and frequent DJ stent changes are very important in patients with urolithiasis.
Isoliert hochfrequente vestibuläre Läsion bei Patienten mit chronischen Schwindelbeschwerden
Authors: Hülse Roland , Hülse Manfred , Hörmann Karl , Hölzl Matthias , Birk Richard , Wenzel Angela 
Published: May 2017

Zusammenfassung
In der vorliegenden Studie wurde bei 72 Patienten, die zum Zeitpunkt der Untersuchung bereits seit mehr als 3 Monaten unter Schwindelbeschwerden litten und bei denen bisher keine peripher-vestibuläre Genese der Beschwerden mittels bithermischer und rotatorischer Testung nachgewiesen werden konnte, der hochfrequente Anteil des vestibulo-okulären Reflexbogens mittels des Videokopfimpulstestes (vKIT) analysiert.
Hierzu wurde der vKIT bei 72 Patienten retrospektiv ausgewertet und mit den Ergebnissen von Rotatorik und Kalorik verglichen. Analysiert wurde beim vKIT das Auftreten von Catch-Up Sakkaden sowie der Gain bzw. Gainseparation.
10 Patienten (n=10; 13,8%) zeigten einen pathologischen veränderten hVOR-Bogen bei hochfrequenter Überprüfung mittels vKIT. Der mittlere Gain der restlichen Gruppe (n=62, 86,2%) zeigte sich mit 0,85 bei horizontaler Testung nach rechts sowie mit 0,87 bei 60 ms bei horizontaler Testung nach links normwertig.
Bei Patienten mit chronischen Schwindelbeschwerden, die in der klassischen vestibulären Routinediagnostik mit Kalorik und Rotatorik keine Pathologien aufweisen, sollte eine komplette rezeptor- und frequenzspezifische Diagnostik durchgeführt werden, um eine isoliertes hochfrequentes Schädigungsmuster des vestibulookulären Reflexbogens objektivieren und dokumentieren zu können. Bei einer unklaren Begutachtungssituation sollte daher diese erweiterte Schwindeldiagnostik nicht mehr fehlen.
The challenge of transformative experiences for advance directives: predicting a future with Alzheimer’s disease
Authors: Boerstler Kyle 
Published: May 2017

AbstractSome of the experiences that are possible in life are not relatable to others, nor can one learn about them in other ways, at least not in the sense of what it is like to have lived the experience. L.A. Paul calls these kinds of experiences transformative experiences. This article will incorporate Paul’s concept into an argument that undermines the moral authority of advance directives in situations where the instructions stated in the directive are in direct conflict with the contemporary interests of a patient who suffers from Alzheimer’s disease. Though the conclusion of this paper will be similar to many others in the literature, namely that advance directives should not in all cases be the final authority on how to respect a patient’s autonomy, this article will argue for this kind of a thesis in a unique way because it will emphasize the importance of that which no one can know. The argument contends that the lived experience of Alzheimer’s disease is a transformative experience, such that one cannot weigh the subjective value of what it is like to be a person with Alzheimer’s disease in the relevant way to properly assess the possible future interests and preferences when creating an advance directive. This article is published as part of a collection on self-knowledge in and outside of illness.
Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway
Authors: Crişan Tania O. , Cleophas Maartje C. P. , Novakovic Boris , Erler Kathrin , van de Veerdonk Frank L. , Stunnenberg Hendrik G. , Netea Mihai G. , Dinarello Charles A. , Joosten Leo A. B. 
Published: May 2017

SignificanceHyperuricemia is a metabolic condition intrinsic to gout pathogenesis but also associated with other common metabolic inflammatory diseases. The soluble uric acid-induced priming of monocytes determines a unique shift in cytokine production consisting of high interleukin (IL)-1β but low IL-1 receptor antagonist (IL-1Ra). We investigated metabolic sensors and scanned for transcriptomic pathways and kinase activation to provide mechanistic leads for this process. We describe that uric acid suppresses autophagy and diminishes the antiinflammatory capacity of the cell. The consequences of uric acid exposure are broad and can impact a larger spectrum of inflammatory diseases from gout to metabolic, renal, or cardiovascular diseases or cancer.
Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus
Authors: Jakob Burkhard , Kochlamazashvili Gaga , Jäpel Maria , Gauhar Aziz , Bock Hans H. , Maritzen Tanja , Haucke Volker 
Published: May 2017

Significance
The development and function of the brain depend on the migration of neurons from the proliferative zone in which they are born to their final position. Reelin, a signaling molecule implicated in the developmental disorder lissencephaly and associated with neurologic diseases in humans, plays an important role in directing neuronal migration and brain development. Here, we identify intersectin 1, a large scaffold protein genetically linked to Down syndrome, as a component of the Reelin signaling pathway that is important for brain development and Reelin-mediated augmentation of synaptic plasticity, a cellular model for learning and memory.
Parallel Voice Onset Time shift in Chinese Korean
Authors: Jin Wenhua , Silva David J. 
Published: May 2017

Abstract
This study reveals the existence of a Voice Onset Time shift in the Korean spoken by native speakers residing in northeast China, a shift parallel to those reported in other Korean varieties in Korea, the USA, and Canada. The VOT pattern observed in the Chinese Korean community is argued to represent a change that cannot be simply explained in terms of diffusion via recent dialect contact, or as a feature directly inherited from the source language when it was transplanted into China over a century ago. We suggest that behind the parallel VOT shifts is the power of “drift” that drives the different Korean varieties along similar journeys of language evolution. This study presents an intriguing case where internal changes driven by “drift” may actually be initiated and further supported by language/dialect contact.
Relative frequency and the holistic processing of morphology
Authors: Heffernan Kevin , Sato Yo 
Published: May 2017

Abstract
This study presents apparent-time changes in the morphology of the expression mitai-na ‘similar to’. Based on apparent-time data, we argue that the morphological boundary between mitai and the attributive morpheme -na in the phrase mitai-na has disappeared, and that this complex phrase is now processed as a monomorphemic form. We suggest that relative frequency is the key to understanding the results.
We further supplement our argument with data on the standardization of the adverbial adjective form in the Kansai dialect. Young speakers overwhelmingly use the standard form of adverbials for all adjectives except two: yō ‘a lot, well’ and hayō ‘quickly, early’ (instead of Standard Japanese yoku and hayaku). The three linguistic forms that display unusual behavior (mitai-na and the adverbial forms of yō and hayō) all have a high relative frequency. We conclude that when a complex form occurs more frequently than its components (high relative frequency), then it behaves as a monomorphemic unit. The irregular adverbial forms are leftover from an obsolete system, in the same way that many English irregular past forms are leftover from the Germanic strong verb system. In contrast, the irregular form mitai-na emerged from and competes with the regular inflection paradigm for mitai, illustrating a previously undocumented path for the diachronic emergence of irregular morphology.
A corpus-based analysis of word order variation in Yami relative clause construction
Authors: Chang Hui-Huan , Rau D. Victoria 
Published: May 2017

AbstractYami relative clauses (RCs) can either precede the head noun, for example,kanakan‘child,’ as inko ni-ma-cita o [ji yákneng] a kanakan‘I saw the child who cannot hold still’, functioning as restrictive RCs ([RC] + a + Head NP), or follow it as inko ni-ma-cita o kanakan a [ji yákneng]‘I saw that child, who cannot hold still’, functioning as nonrestrictive RCs for complementation strategy (Head NP + a + [RC]). The VARBRUL results demonstrate that head final RCs are predominant in Yami, and Yami speakers use them to connect the given referent with the previous discourse to convey given information. The study found that Subject head nouns outnumber other grammatical roles of head NPs, and that Subject head noun with Subject RC construction is produced more than any other RC constructions, which indicates that Yami RCs are used to modify the Subject for topic continuity.
Strategic maneuvering with presentational choices in Corporate Social Responsibility (CSR) reports
Authors: Gâţă Anca 
Published: May 2017

Abstract
In the framework of the extended pragma-dialectical theory of argumentation, Corporate Social Responsibility (CSR) reporting is approached in this study as a particular communicative activity type, which can be reconstructed as part of a critical discussion. CSR reports excerpts are viewed in the analysis as parts of a virtual critical discussion in which a company acts as a protagonist maneuvering strategically to defend the standpoint according to which the business is operated ethically, and to convince the audience about what is mentioned in the standpoint. The reconstructed standpoint of a CSR report, We are doing business responsibly, may be regarded as stereotypical, since it corresponds to the institutional point of this regulated type of communicative activity. In the first part of the study, a brief overview is given of the CSR reporting activity, then the concept of strategic maneuvering is presented, under its three aspects (topical potential, audience demand, and presentational techniques), as well as the notion of communicative activity type, with a highlight on the role of the (macro-)context and of institutional preconditions in analytical studies on argumentation. The analysis in the latter part of the study concerns presentational techniques used by the protagonist in the confrontation and in the argumentation stages in CSR reporting, in order to reconcile rhetorical and dialectical aims by maneuvering strategically. The coordinatively and the subordinatively compound structure of argumentation, the symptomatic argument scheme, as well as reformulations of the standpoint, use of emotionally endowed words, concentration of the arguments in the form of nominal sentences acting as headings are among the most important presentational devices constitutive of argumentative moves aimed at convincing the audience that the company acts ethically, but also at promoting a positive image of its business responsibility, which appears to be the ground for winning the discussion.
Practical reasoning in corporate communication with multiple audiences
Authors: Palmieri Rudi , Mazzali-Lurati Sabrina 
Published: May 2017

AbstractCorporate strategic communication has to be designed by considering multiple audiences of stakeholders. In this paper, we study the connection between the audience structure of corporate messages and the structure of the practical argumentation advanced to persuasively justify a business proposal. To this purpose, we combine a conceptual and analytical framework for the reconstruction of multiple audiences – theText Stakeholdersmodel (Palmieri & Mazzali 2016), with a conceptual and analytical framework for the reconstruction of argument schemes – theArgumentum Model of Topics(Rigotti & Greco Morasso 2010). A takeover proposal made by Ryanair for Aer Lingus is examined as an illustrative case in which this integrated framework is applied. We focus our analysis on Ryanair’s offer document to show how the particular structure of the audience is reflected in the selection of specific value and goal premises (endoxa) and in the activation of specific inferential relations (maxims) of practical reasoning.
Effect of epigallocatechin-3-gallate on the increase in type II collagen accumulation in cartilage-like MSC sheets
Authors: Sato Keigo , Mera Hisashi , Wakitani Shigeyuki , Takagi Mutsumi 
Published: May 2017

Abstract
With the aim to increase type II collagen content in the scaffold-free cartilage-like cell sheet using human bone marrow mesenchymal stem cells, we examined the effect of epigallocatechin-3-gallate (EGCG) addition to the chondrogenic medium for the cell sheet culture. The addition of EGCG (10 μM) increased the content of type II collagen 2-fold, while the addition did not markedly change the expression level of the genes encoding type II collagen and Sox 9. The reactive oxygen species level in the cells in cell sheets was thought to be too low to suppress the accumulation of type II collagen. On the other hand, the addition of EGCG markedly decreased both the matrix metalloproteinase-13 concentration in the supernatant of cell sheet culture and the type II collagen degradation activity in that supernatant. Taken together, EGCG may enhance the accumulation of type II collagen by suppressing type II collagen degradation.
Identification and positional distribution analysis of transcription factor binding sites for genes from the wheat fl-cDNA sequences
Authors: Chen Zhen-Yong , Guo Xiao-Jiang , Chen Zhong-Xu , Chen Wei-Ying , Wang Ji-Rui 
Published: May 2017

Abstract
The binding sites of transcription factors (TFs) in upstream DNA regions are called transcription factor binding sites (TFBSs). TFBSs are important elements for regulating gene expression. To date, there have been few studies on the profiles of TFBSs in plants. In total, 4,873 sequences with 5ʹ upstream regions from 8530 wheat fl-cDNA sequences were used to predict TFBSs. We found 4572 TFBSs for the MADS TF family, which was twice as many as for bHLH (1951), B3 (1951), HB superfamily (1914), ERF (1820), and AP2/ERF (1725) TFs, and was approximately four times higher than the remaining TFBS types. The percentage of TFBSs and TF members showed a distinct distribution in different tissues. Overall, the distribution of TFBSs in the upstream regions of wheat fl-cDNA sequences had significant difference. Meanwhile, high frequencies of some types of TFBSs were found in specific regions in the upstream sequences. Both TFs and fl-cDNA with TFBSs predicted in the same tissues exhibited specific distribution preferences for regulating gene expression. The tissue-specific analysis of TFs and fl-cDNA with TFBSs provides useful information for functional research, and can be used to identify relationships between tissue-specific TFs and fl-cDNA with TFBSs. Moreover, the positional distribution of TFBSs indicates that some types of wheat TFBS have different positional distribution preferences in the upstream regions of genes.
Pleiotropic functions of the yeast Greatwall-family protein kinase Rim15p: a novel target for the control of alcoholic fermentation
Authors: Watanabe Daisuke , Takagi Hiroshi 
Published: May 2017

Abstract
Rim15p, a Greatwall-family protein kinase in yeast Saccharomyces cerevisiae, is required for cellular nutrient responses, such as the entry into quiescence and the induction of meiosis and sporulation. In higher eukaryotes, the orthologous gene products are commonly involved in the cell cycle G2/M transition. How are these pleiotropic functions generated from a single family of protein kinases? Recent advances in both research fields have identified the conserved Greatwall-mediated signaling pathway and a variety of downstream target molecules. In addition, our studies of S. cerevisiae sake yeast strains revealed that Rim15p also plays a significant role in the control of alcoholic fermentation. Despite an extensive history of research on glycolysis and alcoholic fermentation, there has been no critical clue to artificial modification of fermentation performance of yeast cells. Our finding of an in vivo metabolic regulatory mechanism is expected to provide a major breakthrough in yeast breeding technologies for fermentation applications.