bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bilan d'une recherche des Salmonella dans la viande hachée par immunofluorescence
Authors: Catsaras Marc 
Published: February 2018

La recherche des Salmonella dans 10 g, 1 g ou 0,1 g, qui se traduit par 68 résultats faussement négatifs sur 960, par la voie de la bactériologie classique, est positive 67 fois par immunofluorescence.
Pour 320 séries de tubes (de 10-2 à 10-8), 39 d’entre elles permettent d’obtenir un résultat supérieur par immunofluorescence par rapport à la bactériologie classique. Dans la très large majorité des cas il y a seulement 1 tube d’écart.
Effet de la vasopressine sur la fermeture de la gouttière œsophagienne de la chèvre
Authors: Brugère Henri , Mikhaïl M. , Le Bars Henri 
Published: February 2018

Vasopressin effect on closure of reticular groove of goat
Closure of the reticular groove of the goat occurs after an intravenous injection of vasopressin (0.25 i.u./kg).
Recherche des résidus dans les animaux et les viandes fraîches
Authors: Willemart Jean-Pierre , Bouffault Jean-Claude , Egron L. 
Published: February 2018

Deux Directives récentes (85/358/CEE et 86/469/CEE) traitent du problème de la recherche des résidus dans les animaux vivants et dans les viandes fraîches. Elles énoncent un plan de travail qui paraît complet, coordonné et ambitieux.
Néanmoins, un travail considérable est à faire pour mettre au point les méthodes communes nécessaires et s’assurer de leur application homogène dans les 12 Etats membres. Ceci demandera plusieurs années.
En outre, on peut estimer que le coût de la mise en œuvre de ces Directives posera un problème financier dont la solution n’est pas en vue.
Dermatite staphylococcique du mouton compliquée d’ecthyma : à propos de deux cas
Authors: Gourreau Jean-Marie , Louzis Claude , Rehby Liliane , Capafons Michèle , Gente Dominique , Le Doujet Claudine 
Published: February 2018

Staphylococcal dermatitis of sheep associated with contagious pustular dermatitis : study of two cases.
Staphylococcal dermatitis of sheep is a probably frequent but unrecognised affection in France. It can become complicated with contagious pustular dermatitis as the authors describe it through these two observations.
Les perspectives en matière de substances d'intervention thérapeutique et d’aide à la production animale
Authors: Ruckebusch Yves , Raynaud J.-P. 
Published: February 2018

Perspectives in therapeutics and animal health control
The chemicals in the future will be not only for the prevention or treatment of innumerable diseases but for animal health control and improvement of the quality of foods. The next step involves slow releasing systems, immunostimulants, more selective antiinflammatory weapons and chemical restraint. Substances able to promote a quality of food as a correct energy to nutrient ratio will be the challenge of the future.
Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome
Authors: Chandra Smitha CH , Sailakshmi Mo Orkoth Prasannan Anantha , Nagaratnamma Rangaiah 
Published: February 2018

ABSTRACTIn women of reproductive age polycystic ovary syndrome (PCOS) is the common endocrine disorder. It is one of the common causes of infertility due to anovulation. There is no single criterion for the diagnosis of this syndrome. It is crucial to diagnose PCOS early in its course since it has lifelong implications with increased risk for metabolic syndrome, type II Diabetes mellitus (DM), cardiovascular disease, endometrial hyperplasia, infertility and depression. Screening for the impaired glucose (IGT), allows for proper and timely prevention and management of complications. In this cross sectional study, we planned to detect the prevalence of impaired glucose tolerance and diabetes in women with PCOS which will facilitate prevention of long term sequelae. We also studied the extent of the risk for diabetes in patients with PCOS in relation to age, socioeconomic status, rural and urban areas, BMI, waist/hip circumference ratio, family history of PCOS and diabetes mellitusHow to cite this articleSmitha CHC, Sailakshmi MOPA, Nagaratnamma R. Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome. J Med Sci 2017;3(4):116-118.
Novel thermocouples for automotive applications
Authors: Gierth Paul , Rebenklau Lars , Augsburg Klaus , Bachmann Eric , Niedermeyer Lars 
Published: February 2018

Abstract. Measurement of temperatures in engine and exhaust systems in automotive
applications is necessary for thermal protection of the parts and optimizing
of the combustion process. State-of-the-art temperature sensors are very
limited in their response characteristic and installation space requirement.
Miniaturized sensor concepts with a customizable geometry are needed. The
basic idea of this novel sensor concept is to use thick-film technology on
component surfaces. Different standardized and especially nonstandard
material combinations of thermocouples have been produced for the validation
of this technology concept. Application-oriented measurements took place in
the exhaust system of a test vehicle and were compared to standard laboratory
conditions.
Een Europese pijler van sociale rechten
Authors: Pennings F.J.L. 
Published: February 2018

Een Europese pijler van sociale rechten
Op 26 april 2017 heeft de Europese Commissie de aanbeveling voor een Europese pijler van sociale rechten gepubliceerd. Dit is een aanbeveling die ook voorgelegd wordt aan het Europees Parlement en de Europese Raad om deze te onderschrijven. De aanbeveling kent een twintigtal onderwerpen, waarbij de lat veelal hoger wordt gelegd dan in het Handvest van de Grondrechten. Het bijbehorende werkprogramma straalt veel ambitie uit om de sociale dimensie van de Unie daadwerkelijk te versterken. Het belang van de pijler lijkt te liggen in daadwerkelijke uitvoering van dit programma.Aanbeveling van 26 april 2017 voor een Europese pijler van sociale rechten COM(2017)251
Carbon: Chlorophyll Ratios and Net Primary Productivity of Subarctic Pacific Surface Waters Derived From Autonomous Shipboard Sensors
Authors: Burt William J. , Westberry Toby K. , Behrenfeld Michael J. , Zeng Chen , Izett Robert W. , Tortell Philippe D. 
Published: February 2018

AbstractWe present optically derived estimates of phytoplankton carbon (Cphyto) and chlorophyll a concentration (Chl) across a wide range of productivity and hydrographic regimes in the Subarctic Pacific Ocean. Our high‐frequency measurements capture changes in Cphyto and Chl across regional gradients in macronutrient and micronutrient limitations and submesoscale hydrographic frontal zones. Throughout the majority of our survey region, carbon to chlorophyll ratios (Cphyto:Chl) ranged between 50 and 100. Lower values (10–20) were constrained to the highly productive coastal upwelling system along Vancouver Island, whereas higher estimated values (>200) were found directly off the southern British Columbia continental shelf. Further offshore, Cphyto:Chl was less variable, ranging from 50 to 80 in high nutrient low Chl waters in June and from 80 to 120 in the Gulf of Alaska in July. Much of the variability in Cphyto:Chl throughout the study region could be explained by mixed‐layer light levels (i.e., photoacclimation), with additional variability attributed to nutrient‐controlled changes in phytoplankton growth rates in some regions. Elevated Cphyto:Chl ratios resulting from apparent nutrient stress were found in areas of low macronutrient concentrations. In contrast, iron‐limited waters exhibited Cphyto:Chl ratios lower than predicted from the photoacclimation model. Applying the carbon‐based production model, we derived Cphyto and Chl‐based estimates of net primary productivity, which showed good coherence with independent 14C uptake measurements. Our results highlight the utility of ship‐board optical data to examine phytoplankton physiological ecology and productivity in surface marine waters.
Environmental Effects on Mesozooplankton Size Structure and Export Flux at Station ALOHA, North Pacific Subtropical Gyre
Authors: Valencia Bellineth , Décima Moira , Landry Michael R. 
Published: February 2018

AbstractUsing size‐fractionated mesozooplankton biomass data collected over 23 years (1994–2016) of increasing primary production (PP) at station ALOHA (A Long‐Term Oligotrophic Habitat Assessment), we evaluate how changing environmental conditions affect mesozooplankton size structure, trophic cycling, and export fluxes in the subtropical North Pacific. From generalized additive model analysis, size structure is significantly influenced by a nonlinear relationship with sea surface temperature that is mainly driven by the strong 1997–1998 El Niño and a positive and linear relationship with PP. Increasing PP has more strongly enhanced the biomass of smaller (0.2–0.5 mm) and larger (>5 mm) mesozooplankton, increasing evenness of the biomass spectra, while animals of 2–5 mm, the major size class for vertically migrating mesozooplankton, show no long‐term trend. Measured PP is sufficient to meet feeding requirements that satisfy mesozooplankton respiration and growth rates, as determined by commonly used empirical relationships based on animal size and temperature, consistent with a tightly coupled food web with one intermediate level for protistan consumers. Estimated fecal pellet production suggests an enhanced contribution of mesozooplankton to passive particle export relative to the material collected in 150 m sediment traps. In contrast, the biomass of vertically migrants does not vary systematically with PP due to the varying responses of the different size classes. These results illustrate some complexities in understanding how varying environmental conditions can affect carbon cycling and export processes at the community level in open‐ocean oligotrophic systems, which need to be confirmed and better understood by process‐oriented mechanistic study.
Euler‐Vector Clustering of GPS Velocities Defines Microplate Geometry in Southwest Japan
Authors: Savage J. C. 
Published: February 2018

AbstractI have used Euler‐vector clustering to assign 469 GEONET stations in southwest Japan to k clusters (k = 2, 3,..., 9) so that, for any k, the velocities of stations within each cluster are most consistent with rigid‐block motion on a sphere. That is, I attempt to explain the raw (i.e., uncorrected for strain accumulation), 1996–2006 velocities of those 469 Global Positioning System stations by rigid motion of k clusters on the surface of a spherical Earth. Because block geometry is maintained as strain accumulates, Euler‐vector clustering may better approximate the block geometry than the values of the associated Euler vectors. The microplate solution for each k is constructed by merging contiguous clusters that have closely similar Euler vectors. The best solution consists of three microplates arranged along the Nankaido Trough‐Ryukyu Trench between the Amurian and Philippine Sea Plates. One of these microplates, the South Kyushu Microplate (an extension of the Ryukyu forearc into the southeast corner of Kyushu), had previously been identified from paleomagnetic rotations. Relative to ITRF2000 the three microplates rotate at different rates about neighboring poles located close to the northwest corner of Shikoku. The microplate model is identical to that proposed in the block model of Wallace et al. (2009, https://doi.org/10.1130/G2522A.1) except in southernmost Kyushu. On Shikoku and Honshu, but not Kyushu, the microplate model is consistent with that proposed in the block models of Nishimura and Hashimoto (2006, https://doi.org/10.1016/j.tecto.2006.04.017) and Loveless and Meade (2010, https://doi.org/10.1029/2008JB006248) without the low‐slip‐rate boundaries proposed in the latter.
Structural Geology and the Seismotectonics of the 2004 Great Sumatran Earthquake
Authors: Lister G. S. , Forster M. A. , Muston J. E. , Mousavi S. , Hejrani B. 
Published: February 2018

AbstractThe paper sets out a method for structural analysis of seismotectonic data using centroid moment tensors and associated hypocenters from the Global Centroid Moment Tensor project, here illustrated for aftershocks from the 2004 great Sumatran earthquake. We show that the Sumatran segments of the megathrust were subject to compression in a direction near to orthogonal with the margin trend, consistent with the effect of relative movement of the adjacent tectonic plates. In contrast, the crust above the Andaman Sea segments was subject to margin‐orthogonal extension, consistent with motion toward the gravitational potential well accumulated due to prior lateral (westward) rollback of the subducting edge of the northward moving Indian plate. Since this potential well is largely defined by topography, this episode of margin‐orthogonal extension is at least in part “gravity driven.” It did not last long. Within 15 months, an earthquake cluster across an Andaman Sea spreading segment showed a return to kinematics driven by relative plate motion. The transition can be explained if fluid activity temporarily reduced basal friction (or effective stress) but then led to healing so that the megathrust once again began to develop friction‐locked segments. The influence of slab rollback is in developing a gravitational potential well facing the megathrust, hence drawing the overriding crust toward it in the immediate postrupture phase while the megathrust is in a weakened state. Plate tectonics dominates during interseismic gaps, once the megathrust heals, and regains frictional resistance.
Polycationic Synergistic Antibacterial Agents with Multiple Functional Components for Efficient Anti‐Infective Therapy
Authors: Zhu Yiwen , Xu Chen , Zhang Na , Ding Xiaokang , Yu Bingran , Xu Fu‐Jian 
Published: February 2018

AbstractMultifunctional antibacterial photodynamic therapy is a promising method to combat regular and multidrug‐resistant bacteria. In this work, eosin Y (EY)‐based antibacterial polycations (EY‐QEGEDR, R = CH3 or C6H13) with versatile types of functional components including quaternary ammonium, photosensitizer, primary amine, and hydroxyl species are readily synthesized based on simple ring‐opening reactions. In the presence of light irradiation, such antibacterial polymers exhibit high antibacterial efficiency against both Escherichia coli and Staphylococcus aureus. In particular, EY‐QEGEDR elicits a remarkable synergistic antibacterial activity owing to the combined photodynamic and quaternary ammonium antibacterial effects. Due to its rich primary amine groups, EY‐QEGEDR also can be readily coated on different substrates, such as glass slides and nonwoven fabrics via an adhesive layer of polydopamine. The resultant surface coating of EY‐QEGEDCH3 (s‐EY‐QEGEDCH3) produces excellent in vitro antibacterial efficacy. The plentiful hydroxyl groups impart s‐EY‐QEGEDCH3 with potential antifouling capability against dead bacteria. The antibacterial polymer coatings also demonstrate low cytotoxicity and good hemocompatibility. More importantly, s‐EY‐QEGEDCH3 significantly enhances in vivo therapeutic effects on an infected rat model. The present work provides an efficient strategy for the rational design of high‐performance antibacterial materials to fight biomedical device‐associated infections.
The Endeavor of Diarylethenes: New Structures, High Performance, and Bright Future
Authors: Zhang Junji , Tian He 
Published: February 2018

AbstractPhotochromism is a term that describes the photoreversible isomerization between two different states or isomers with distinct performances. Among all the photochromic molecule family, diarylethene is considered one of the most popular star molecules on account of its fast photoresponsibility, excellent thermal stability, fatigue resistance, high photoreaction quantum yield, and conversion ratio as well as good performances in both solution and solid phases. In the past decades, the development of diarylethene is witnessed in molecule design, solution applications, surface/interface assembly, bulky crystals and polymers, optic‐electronic devices fabrication, and biotechnology. This review mainly focuses on the latest development of diarylethenes in recent five years and commences with the newly designed molecular structures with functional ethene bridges and aryl moieties. The application of diarylethenes in materials science, soft materials, molecular data processing, and biomaterials, is further discussed in prospect. A brief summary is given in the end of the review together with some perspectives.
Mn versus Al in Layered Oxide Cathodes in Lithium‐Ion Batteries: A Comprehensive Evaluation on Long‐Term Cyclability
Authors: Li Wangda , Liu Xiaoming , Celio Hugo , Smith Patrick , Dolocan Andrei , Chi Miaofang , Manthiram Arumugam 
Published: February 2018

AbstractNickel‐rich layered oxide cathodes with the composition LiNi1−x−yCoxMnyO2 (NCM, (1−x−y) ≥ 0.6) are under intense scrutiny recently to contend with commercial LiNi0.8Co0.15Al0.05O2 (NCA) for high‐energy‐density batteries for electric vehicles. However, a comprehensive assessment of their electrochemical durability is currently lacking. Herein, two in‐house cathodes, LiNi0.8Co0.15Al0.05O2 and LiNi0.7Co0.15Mn0.15O2, are investigated in a high‐voltage graphite full cell over 1500 charge‐discharge cycles (≈5–10 year service life in vehicles). Despite a lower nickel content, NCM shows more performance deterioration than NCA. Critical underlying degradation processes, including chemical, structural, and mechanical aspects, are analyzed via an arsenal of characterization techniques. Overall, Mn substitution appears far less effective than Al in suppressing active mass dissolution and irreversible phase transitions of the layered oxide cathodes. The active mass dissolution (and crossover) accelerates capacity decline with sustained parasitic reactions on the graphite anode, while the phase transitions are primarily responsible for cell resistance increase and voltage fade. With Al doping, on the other hand, secondary particle pulverization is the more limiting factor for long‐term cyclability compared to Mn. These results establish a fundamental guideline for designing high‐performing Ni‐rich NCM cathodes as a compelling alternative to NCA and other compositions for electric vehicle applications.
Rivaroxaban plasma levels in acute ischemic stroke and intracerebral hemorrhage
Authors: Seiffge David J. , Kägi Georg , Michel Patrik , Fischer Urs , Béjot Yannick , Wegener Susanne , Zedde Marialuisa , Turc Guillaume , Cordonnier Charlotte , Sandor Peter S. , Rodier Gilles , Zini Andrea , Cappellari Manuel , Schädelin Sabine , Polymeris Alexandros A. , Werring David , Thilemann Sebastian , Maestrini Ilaria , Berge Eivind , Traenka Christopher , Vehoff Jochen , De Marchis Gian Marco , Kapauer Monika , Peters Nils , Sirimarco Gaia , Bonati Leo H. , Arnold Marcel , Lyrer Philippe A. , De Maistre Emmanuel , Luft Andreas , Tsakiris Dimtrios A. , Engelter Stefan T. ,   on behalf of the Novel Oral Anticoagulants in Stroke Patients study group
Published: February 2018

ObjectiveInformation about rivaroxaban plasma level (RivLev) may guide treatment decisions in patients with acute ischemic stroke (AIS) and intracerebral hemorrhage (ICH) taking rivaroxaban.MethodsIn a multicenter registry‐based study (Novel Oral Anticoagulants in Stroke Patients collaboration; ClinicalTrials.gov: NCT02353585) of patients with stroke while taking rivaroxaban, we compared RivLev in patients with AIS and ICH. We determined how many AIS patients had RivLev ≤ 100ng/ml, indicating possible eligibility for thrombolysis, and how many ICH patients had RivLev ≥ 75ng/ml, making them possibly eligible for the use of specific reversal agents. We explored factors associated with RivLev (Spearman correlation, regression models) and studied the sensitivity and specificity of international normalized ratio (INR) thresholds to substitute RivLev using cross tables and receiver operating characteristic curves.ResultsAmong 241 patients (median age = 80 years, interquartile range [IQR] = 73–84; median time from onset to admission = 2 hours, IQR = 1–4.5 hours; median RivLev = 89ng/ml, IQR = 31–194), 190 had AIS and 51 had ICH. RivLev was similar in AIS patients (82ng/ml, IQR = 30–202) and ICH patients (102ng/ml, IQR = 51–165; p = 0.24). Trough RivLev(≤137ng/ml) occurred in 126/190 (66.3%) AIS and 34/51 (66.7%) ICH patients. Among AIS patients, 108/190 (56.8%) had RivLev ≤ 100ng/ml. In ICH patients, 33/51 (64.7%) had RivLev ≥ 75ng/ml. RivLev was associated with rivaroxaban dosage, and inversely with renal function and time since last intake (each p < 0.05). INR ≤ 1.0 had a specificity of 98.9% and a sensitivity of 25.7% to predict RivLev ≤ 100ng/ml. INR ≥ 1.4 had a sensitivity of 59.3% and specificity of 90.1% to predict RivLev ≥ 75ng/ml.InterpretationRivLev did not differ between patients with AIS and ICH. Half of the patients with AIS under rivaroxaban had a RivLev low enough to consider thrombolysis. In ICH patients, two‐thirds had a RivLev high enough to meet the eligibility for the use of a specific reversal agent. INR thresholds perform poorly to inform treatment decisions in individual patients. Ann Neurol 2018;83:451–459
Mutations in MICAL‐1cause autosomal‐dominant lateral temporal epilepsy
Authors: Dazzo Emanuela , Rehberg Kati , Michelucci Roberto , Passarelli Daniela , Boniver Clementina , Vianello Dri Valeria , Striano Pasquale , Striano Salvatore , Pasterkamp R. Jeroen , Nobile Carlo 
Published: February 2018

ObjectiveAutosomal‐dominant lateral temporal epilepsy (ADLTE) is a genetic focal epilepsy characterized by auditory symptoms. Two genes, LGI1 and RELN, encoding secreted proteins, are implicated in the etiology of ADLTE, but half of the affected families remain genetically unsolved, and the underlying molecular mechanisms are yet to be clarified. We aimed to identify additional genes causing ADLTE to better understand the genetic basis and molecular pathway underlying this epileptic disorder.MethodsA cohort of Italian ADLTE families was examined by whole exome sequencing combined with genome‐wide single‐nucleotide polymorphism‐array linkage analysis.ResultsWe identified two ADLTE‐causing variants in the MICAL‐1 gene: a p.Gly150Ser substitution occurring in the enzymatically active monooxygenase (MO) domain and a p.Ala1065fs frameshift indel in the C‐terminal domain, which inhibits the oxidoreductase activity of the MO domain. Each variant segregated with ADLTE in a single family. Examination of candidate variants in additional genes excluded their implication in ADLTE. In cell‐based assays, both variants significantly increased MICAL‐1 oxidoreductase activity and induced cell contraction in COS7 cells, which likely resulted from deregulation of F‐actin dynamics.InterpretationMICAL‐1 oxidoreductase activity induces disassembly of actin filaments, thereby regulating the organization of the actin cytoskeleton in developing and adult neurons and in other cell types. This suggests that dysregulation of the actin cytoskeleton dynamics is a likely mechanism by which MICAL‐1 pathogenic variants lead to ADLTE. Ann Neurol 2018;83:483–493