bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fun By Design: The Game Design Activity and Its Iterative Process as (Playful) Learning Practices
Authors: Mariani Ilaria , Ackermann Judith 
Published: June 2016

Abstract
THIS CONTRIBUTION PROPOSES A CRITICAL REVIEW OF THE RESULTS OF A WORKSHOP HELD AT POLITECNICO DI MILANO PROBLEMATISING HOW PLAYFULNESS AND ‘FUN BY DESIGN’ AFFECT GAME DESIGN ACTIVITIES AND CONTRIBUTE TO GIVING STUDENTS A DIFFERENT AWARENESS OF THE PLAY EXPERIENCE. THE PRESENTED ACTIVITIES ARE PART OF THE AUTHORS’ JOINT RESEARCH IN THE DOMAIN OF SITUATED GAMING AS A FORM OF PLAYFUL LEARNING IN HIGHER EDUCATION, WHICH INVESTIGATES THE PART OF BOTH THE DESIGNERS AND THE PLAYERS (ACKERMANN & MARIANI, 2015). THE ANALYSIS INVESTIGATES HOW THE ITERATIVE DESIGN PROCESS SIMULTANEOUSLY ELICITS FUN AND ACTIVATES REFLECTIONS ON THE GAME DESIGN PRACTICE AND THE PLAYTESTING ACTIVITY AS A NODAL MOMENT FOR PLAYERS AND DESIGNERS, WHERE SERIOUSNESS AND PLAYFULNESS INTERSECT.
ALLOWING AND REQUIRING PLAYFUL PARTICIPATION ON MULTIPLE LEVELS, AND AIMING TO EMPHASISE THE PLAYERS’ PERSPECTIVES, WE ASKED 45 STUDENTS TO (1) DESIGN LOCATION BASED MOBILE GAMES, (2) PERFORM THE OBSERVATION/ VERIFICATION PROCESS AND (3) EXPLORE ITS ELUSIVE AND CHALLENGING PHASES. DATA WAS COLLECTED FROM RAPID ETHNOGRAPHIES AND QUESTIONNAIRES COMPILED IN THE PROCESS.
THE CONTRIBUTION EXPANDS THE REASONING FROM THE FUNDAMENTAL DISCOURSE OF MEANINGS EMBEDDED AND COMMUNICATED THROUGH GAMES, TO THE IMPORTANCE OF THE GAME DESIGN ACTIVITY AS A RECURSIVE PROCESS OF KNOWLEDGE ACQUISITION AND AS A SPECIFIC FORM OF PLAYFUL LEARNING.
Making Art – Taking Part!
Authors: Zobl Elke , Huber Laila 
Published: June 2016

Abstract
HOW CAN WE OPEN PARTICIPATORY SPACES PLAYFULLY AND CRITICALLY? OUR ARTICLE RAISES THIS QUESTION IN THE CONTEXT OF A RESEARCH PROJECT AT THE INTERSECTION OF PARTICIPATORY AND INTERVENTIONIST ART, CRITICAL ART EDUCATION AND PARTICIPATORY RESEARCH. IN THE PROJECT “MAKING ART – TAKING PART!” (WWW.TAKINGPART.AT), WHICH THE AUTHORS, ALONG WITH ADDITIONAL TEAM MEMBERS, CONDUCTED WITH STUDENTS AGED 14–16 IN SALZBURG, AUSTRIA, AN ARTISTIC INTERVENTION IN PUBLIC SPACE WAS DEVELOPED BASED ON THE IDEAS, EXPERIENCES, AND DESIRES OF THE STUDENTS. IN A COLLABORATIVE PROCESS, WE EXPLORED STRATEGIES FOR SELF-EMPOWERMENT, DECONSTRUCTION OF ESTABLISHED KNOWLEDGE AND POWER RELATIONS, AND APPROPRIATION BY ARTISTIC AND ART MEDIATION MEANS AROUND THE TOPIC OF “LIVING TOGETHER”. IN THIS PAPER, WE ARGUE THAT BY EMPLOYING SUCH STRATEGIES, A LIMINAL SPACE CAN BE OPENED – IN A PLAYFUL, YET CRITICAL WAY – IN WHICH THE MEANING OF PARTICIPATION IS COLLABORATIVELY NEGOTIATED.
Learning, Gaming, Designing: Using Playful Participation to Create Learning Games Together with High School Students
Authors: Kayali Fares , Schwarz Vera , Götzenbrucker Gerit , Purgathofer Peter 
Published: June 2016

Abstract
THE PAPER DEALS WITH DEVELOPING LEARNING GAMES IN THE AREA OF INFORMATICS AND SOCIETY IN AN INTERDISCIPLINARY COLLABORATION OF RESEARCHERS, UNIVERSITY STUDENTS, AND HIGH SCHOOL STUDENTS IN VIENNA, AUSTRIA. IN THIS PROJECT, WE APPLY MIXED METHODS TO ENSURE MEANINGFUL RESULTS. PLAYING RESEARCH AND GAME ANALYSIS ARE SUPPOSED TO PREPARE SECONDARY SCHOOL STUDENTS FOR THE TASK OF DESIGNING AND CREATING LEARNING GAMES IN A PARTICIPATORY SETTING, USING EXPLORATIVE DESIGN AND DESIGN THINKING. THE STUDENTS ARE SUPPORTED IN DOING SO BY THE ACADEMICS. THE RESEARCHERS WILL ALSO EVALUATE THE OUTCOMES. THE PAPER PRESENTS THE FIRST EXAMPLES OF INFORMATICS AND SOCIETY LEARNING GAMES AND USE THE FOLLOWING APPROACHES TO TRIGGER LEARNING EXPERIENCES: HUMOR AND EXAGGERATION, SHIFT OF PERSPECTIVE, THE PRESENTATION OF FACTS, AND TRIAL AND ERROR. THESE RESULTS FROM THE EARLY STAGES OF THE PROJECT ARE ENCOURAGING AND HINT AT THE POSSIBLE SUCCESS OF PLAYFUL PARTICIPATION IN THE FIELD OF GAME-BASED LEARNING.
Exchanging Engagement: Alternative Arts Engagement in Latin America
Authors: Elliott Matthew David 
Published: June 2016

Abstract
IN 1973, EDUARDO GALEANO (1940-2015), THE URUGUAYAN WRITER AND JOURNALIST CONCLUDED HIS SEMINAL BOOK OPEN VEINS OF LATIN AMERICA WITH THE FOLLOWING: ‘THE LATIN AMERICAN CAUSE IS ABOVE ALL A SOCIAL CAUSE: THE REBIRTH OF LATIN AMERICA MUST START WITH THE OVERTHROW OF ITS MASTERS, COUNTRY BY COUNTRY. WE ARE ENTERING TIMES OF REBELLION AND CHANGE’ (GALEANO, 1973, P. 261). AS GALEANO STATED, THE OPPRESSION OF POPULATIONS AND THE LOSS OF LIVES THROUGHOUT LATIN AMERICA LED TO ‘TIMES OF REBELLION AND CHANGE’. ARTISTS, ACTIVISTS AND THE WIDER COMMUNITY SOUGHT TO CHALLENGE AND RESIST AUTOCRATIC REGIMES TO SEEK ALTERNATIVE WAYS OF UPHOLDING THEIR DEMOCRATIC AND HUMAN RIGHTS. THESE METHODS AND PRACTICE HAVE TRANSCENDED THE DEMOCRATISATION OF THE CONTINENT IN THE 1980S AND 1990S. THE DESIRE TO ADVOCATE CHANGE THROUGH THE ARTS HAS CONTINUED TO BE RADICAL AND PROPOSES AN ALTERNATIVE WAY OF BEING TO COMMUNITIES IN LATIN AMERICA. HOW CAN THIS PRACTICE BE TRANSPOSED TO BENEFIT THE PERSONAL AND SOCIAL DEVELOPMENT OF YOUNG PEOPLE IN THE UK?
THE AUTHOR’S EXPERIENCE OF WORKING WITH YOUNG PEOPLE AND HIS ENCOUNTERS WITH LATIN AMERICAN ARTS PRACTICE LED TO A NEED TO INTERTWINE THESE PRACTICES AND DEVELOP THEATRE AS A MODEL FOR SOCIAL CHANGE, WHICH ENGAGES THE POLITICAL AND SOCIAL RIGHTS OF YOUNG PEOPLE IN THE UK.
THE PAPER IS A PRODUCT OF A SIX-WEEK PRACTICE-BASED RESEARCH PROJECT IN LATIN AMERICA (CHILE, ARGENTINA AND URUGUAY) THAT EXPLORED INNOVATIVE ARTS ENGAGEMENT FOR MARGINALISED YOUNG PEOPLE. THE RESEARCH WAS UNDERTAKEN AS A MEANS TO DEVELOP A HIGH QUALITY ARTS PROVISION FOR YOUNG PEOPLE IN THE UK. THE PAPER FOCUSES ON THREE AREAS: CONTINUITY, SUSTAINABILITY AND ACTIVISM, AND ASKS THE READER: HOW CAN THEATRE ETHICALLY ENGAGE YOUNG PEOPLE IN THE SOCIAL AND POLITICAL DECISIONS THAT SHAPE THEIR SOCIETY? THE RESEARCH WAS FUNDED BY THE WINSTON CHURCHILL MEMORIAL TRUST.
Histoires naturelles, récits de voyage et géopolitique religieuse dans l’Atlantique français XVIe et XVIIe siècles1
Authors: Lachenicht Susanne 
Published: June 2016

Cet article analyse des histoires naturelles et des récits de voyage d’auteurs français du XVIe siècle en portant attention à la dimension confessionnelle de leur discours. Quelles sont leurs fonctions dans la géopolitique religieuse de l’Atlantique français et, plus particulièrement, dans les luttes entre catholiques et huguenots ? Que deviennent les histoires naturelles et récits de voyages au XVIIe siècle ? Perdent-ils de leur importance dans les polémiques françaises entre protestants et catholiques ? Finalement, la Révocation de l’Édit de Nantes met-elle fin aux projets de colonisation huguenote et aux histoires naturelles et récits de voyage confessionnalisés dans l’Atlantique français ?
Feasibility and Impact of an 8-Week Integrative Yoga Program in People with Moderate Multiple Sclerosis–Related Disability
Authors: Cohen Evan T. , Kietrys David , Fogerite Susan Gould , Silva Mariella , Logan Kristen , Barone Donald A. , Parrott J. Scott 
Published: June 2016

Background: This pilot study determined the feasibility of a specifically designed 8-week yoga program for people with moderate multiple sclerosis (MS)–related disability. We explored the program's effect on quality of life (QOL) and physical and mental performance.
Methods: We used a single-group design with repeated measurements at baseline, postintervention, and 8-week follow-up. Feasibility was examined through cost, recruitment, retention, attendance, and safety. Outcomes included the Multiple Sclerosis Quality of Life Inventory (MSQLI), 12-item Multiple Sclerosis Walking Scale (MSWS-12), Timed 25-Foot Walk test (T25FW), 6-Minute Walk Test (6MWT), Nine-Hole Peg Test (NHPT), Five-Times Sit-to-Stand Test (FTSTS), Multidirectional Reach Test (MDRT), maximum expiratory pressure, and Paced Auditory Serial Addition Test-3″ (PASAT-3″).
Results: Fourteen participants completed the study. The program was feasible. There were significant main effects on the 36-item Short Form Health Status Survey Mental Component Summary (SF-36 MCS), Modified Fatigue Impact Scale (MFIS), Bladder Control Scale (BLCS), Perceived Deficits Questionnaire (PDQ), Mental Health Inventory (MHI), MSWS-12, T25FW, NHPT, PASAT-3″, 6MWT, FTSTS, and MDRT-Back. Improvements were found on the SF-36 MCS, MFIS, BLCS, PDQ, MHI, and MSWS-12 between baseline and postintervention. The effect on PDQ persisted at follow-up. Improvements were found on the T25FW, NHPT, 6MWT, FTSTS, and MDRT-Back between baseline and postintervention that persisted at follow-up. The PASAT-3″ did not change between baseline and postintervention but did between postintervention and follow-up.
Conclusions: The yoga program was safe and feasible. Improvements in certain measures of QOL and performance were seen at postintervention and follow-up.
Multidisciplinary Management of Sexual Dysfunction, Perineal Pain, and Elimination Dysfunction in a Woman with Multiple Sclerosis
Authors: Miletta Michela , Bogliatto Fabrizio , Bacchio Leonardo 
Published: June 2016

Background: Multiple sclerosis (MS) is a chronic disease that commonly affects young women and is associated with sexual dysfunction (SD) and lower anourogenital dysfunction, which affect quality of life. We evaluated the importance of an integrated multidisciplinary approach in the Lower Female Ano-Uro-Genital Network (LFAUGN) to manage a variety of complex symptoms.
Methods: A 40-year-old woman with MS and primary concerns about perineal pain and SD was treated by a trained midwife from the LFAUGN and a physical therapist after a multidisciplinary diagnostic process that included gynecologic evaluation for perineal pain and SD, physiatric assessment, urologic assessment for bladder retention (BR), and surgical examination for obstructed defecation syndrome (ODS). Physical therapy was integrated with pharmacologic therapy for ODS and with self-catheterization for BR.
Results: After 5 months of treatment, the patient reported improvement in functional perineal parameters and perineal pain (visual analogue scale score: 9 at T1 vs. 5 at T2), with resolution of pelvic floor hypertonia. Furthermore, ODS and BR symptoms improved (5-item score: 18 of 20 at T1 vs. 10 of 20 at T2; 1 self-catheterization daily, with postvoid residual volume [PRV] &lt;200 mL at T1 vs. 1 self-catheterization weekly, with PRV &lt;100 mL at T2) and sexual satisfaction increased (Female Sexual Function Index score: 18 of 36 at T1 vs. 23 of 36 at T2).
Conclusions: These results suggest that physical therapy, as an integral component of a multidisciplinary approach in a multiprofessional network, may play a pivotal role in improving anourogenital dysfunction and sexual satisfaction.
Using expert elicitation to quantify catchment water balances and their uncertainties
Authors: Sebok E. , Refsgaard J. C. , Warmink J. J. , Stisen S. , Jensen K. H. 
Published: June 2016

AbstractExpert elicitation with the participation of 35 experts was used to estimate a water balance for the nested Ahlergaarde and Holtum catchments in Western Denmark. Average annual values of precipitation, evapotranspiration, and surface runoff as well as subsurface outflow and recharge and their uncertainty were estimated in a multistep elicitation, where experts first gave their opinion on the probability distribution of their water balance component of interest, then the average annual values and uncertainty of water balance components and catchment‐scale water balances were obtained by reaching consensus during group discussions. The obtained water balance errors for the 1055 km2 Ahlergaarde catchment and 120 km2 Holtum catchment were −5 and −62 mm/yr, respectively, with an uncertainty of 66 and 86 mm/yr, respectively. As an advantage of the expert elicitation, drawing on the intuitive experience and capabilities of experts to assess complex, site‐specific problems, the contribution of independent sources of uncertainties to the total uncertainty was also evaluated similarly to the subsurface outflow component, which traditionally is estimated as the residual of the water balance.
A hybrid statistical‐dynamical framework for meteorological drought prediction: Application to the southwestern United States
Authors: Madadgar Shahrbanou , AghaKouchak Amir , Shukla Shraddhanand , Wood Andrew W. , Cheng Linyin , Hsu Kou‐Lin , Svoboda Mark 
Published: June 2016

AbstractImproving water management in water stressed‐regions requires reliable seasonal precipitation predication, which remains a grand challenge. Numerous statistical and dynamical model simulations have been developed for predicting precipitation. However, both types of models offer limited seasonal predictability. This study outlines a hybrid statistical‐dynamical modeling framework for predicting seasonal precipitation. The dynamical component relies on the physically based North American Multi‐Model Ensemble (NMME) model simulations (99 ensemble members). The statistical component relies on a multivariate Bayesian‐based model that relates precipitation to atmosphere‐ocean teleconnections (also known as an analog‐year statistical model). Here the Pacific Decadal Oscillation (PDO), Multivariate ENSO Index (MEI), and Atlantic Multidecadal Oscillation (AMO) are used in the statistical component. The dynamical and statistical predictions are linked using the so‐called Expert Advice algorithm, which offers an ensemble response (as an alternative to the ensemble mean). The latter part leads to the best precipitation prediction based on contributing statistical and dynamical ensembles. It combines the strength of physically based dynamical simulations and the capability of an analog‐year model. An application of the framework in the southwestern United States, which has suffered from major droughts over the past decade, improves seasonal precipitation predictions (3–5 month lead time) by 5–60% relative to the NMME simulations. Overall, the hybrid framework performs better in predicting negative precipitation anomalies (10–60% improvement over NMME) than positive precipitation anomalies (5–25% improvement over NMME). The results indicate that the framework would likely improve our ability to predict droughts such as the 2012–2014 event in the western United States that resulted in significant socioeconomic impacts.
The role of Equatorial Undercurrent in sustaining the Eastern Indian Ocean upwelling
Authors: Chen Gengxin , Han Weiqing , Shu Yeqiang , Li Yuanlong , Wang Dongxiao , Xie Qiang 
Published: June 2016

AbstractBy combining volume transport and salinity analysis from 1958 to 2014, this paper investigates how the transient Equatorial Undercurrent (EUC) sustains the summer‐fall equatorial eastern Indian Ocean (EIO) upwelling. On seasonal time scales, the EIO upwelling is mainly supplied by the salty water from the western basin through a buffering process: The winter‐spring EUC carries the salty water from the western basin eastward, induces downwelling in the EIO, and pushes portion of the salty water below the central thermocline, which subsequently upwells to the central thermocline during summer‐fall and sustains the EIO upwelling. On interannual time scales, enhanced upwelling occurs during positive Indian Ocean Dipole (+IOD) years. The strong summer‐fall EUC associated with the +IOD supplies water for the intensified upwelling. This research provides new knowledge for basin‐scale mass and property exchanges associated with the EIO upwelling, contributing to our understanding of three‐dimensional ocean circulation and climate variability.
Effect of cyclone Nilofar on mesospheric wave dynamics as inferred from optical nightglow observations from Mount Abu, India
Authors: Singh Ravindra P. , Pallamraju Duggirala 
Published: June 2016

AbstractMesospheric nightglow intensities at three emissions (O2(0–1), OH(6–2) bands, and Na(589.3 nm)) from a low‐latitude location, Gurushikhar, Mount Abu (24.6°N, 72.8°E), in India, showed similar wave features on 26 October 2014 with a common periodicity of around 4 h. A convective activity due to the cyclone Nilofar, which had developed in the Arabian Sea during 25–31 October 2014, was found to be the source as this too showed a gravity wave period coherent with that of the mesospheric emissions on the 26th. The periodicities at the source region were obtained using outgoing longwave radiation fluxes (derived from Kalpana‐1 satellite) which were used as a tracer of tropospheric activity. Cyclone Nilofar had two centers located at a distance of 1103 and 1665 km from the observational station. From the phase offset in time between residuals of O2 and OH emission intensities and the observed common periodicity the vertical phase speed and wavelength have been found to be 1.13 ms−1 and 16.47 km. From the wavelet analyses it is seen that the travel time of the wave from the convection region to O2 emission height was around 8.1 h. From these observations the horizontal phase speed and wavelength of the wave in the mesosphere were calculated to be 37.8 ms−1 and 553 km. These results thus provide not only unambiguous evidence on the vertical coupling of atmospheres engendered by the tropical cyclone Nilofar but also the characteristics of waves that exist during such cyclonic events.
Potential new production in two upwelling regions of the western Arabian Sea: Estimation and comparison
Authors: Liao Xiaomei , Zhan Haigang , Du Yan 
Published: June 2016

AbstractUsing satellite‐derived and in situ data, the wind‐driven potential new production (nitrate supply) for the 300 km wide coastal band in two upwelling regions of the western Arabian Sea (AS) during the southwest monsoon is estimated. The upward nitrate flux to the euphotic zone is generally based on the physical processes of coastal transport (Ekman transport and geostrophic transport) and offshore Ekman pumping. The coastal geostrophic current in the western AS influences the upwelling intensity and latitudinal distributions of nitrate supply. The Oman and Somalia upwelling regions have similar level of potential new production (nitrate supply) during the summer monsoon, while the satellite estimates of primary production off Oman are 2 times greater than those off Somalia. The much higher potential f‐ratio in the Somalia upwelling region indicates that the primary production could be limited by availability of other macronutrients (e.g., silicate). The correlation analysis of the primary production and the aerosol optical thickness shows that the Oman upwelling region displays a stronger coupling between the atmospheric deposition and the phytoplankton abundance. The high summertime dust levels in the atmosphere are suggested to contribute to the high primary production in the Oman upwelling region.
Climatology and linear trends of seasonal water temperature and heat budget in a semienclosed sea connected to the Kuroshio region
Authors: Tsutsumi Eisuke , Guo Xinyu 
Published: June 2016

AbstractThe climatology and linear trend of seasonal water temperature and heat budget in a semienclosed sea connected to the Kuroshio region (Seto Inland Sea: SIS) are investigated by constructing and analyzing a gridded data set of water temperature, salinity, and air‐sea heat fluxes. In the SIS, winter‐time water temperature and ocean heat content (OHC) showed a significant increasing trend while those in summer‐time exhibited no significant change. By analyzing the heat budget between the tendency of ocean heat content ∂OHC/∂t and air‐sea net heat flux Qnet, the driving factor of the winter‐time warming trend in the SIS was identified as autumn Qnet, while the unchanged summer‐time OHC is mainly due to decreased spring‐time oceanic heat transport to the SIS from the Kuroshio region. In addition, we showed that the decreased spring‐time heat transport could have been induced by upwelling due to wind curl and wind speed in the shelf‐slope region, heat transport by the Kuroshio south of Shikoku Island, and freshwater input to the SIS from rivers. The importance of both oceanic and atmospheric forcing mechanisms for explaining variation in the water temperature in coastal areas is demonstrated.
Identification and Characterization of D‐Succinylase, and a Proposed Enzymatic Method for D‐Amino Acid Synthesis
Authors: Sumida Yosuke , Iwai Sachio , Nishiya Yoshiaki , Kumagai Shinya , Yamada Toshihide , Azuma Masayuki 
Published: June 2016

AbstractChiral amino acids are important intermediates for the pharmaceutical industry. We have developed a novel one‐pot enzymatic method for D‐amino acid synthesis by the dynamic kinetic resolution of N‐succinyl‐dl‐amino acids using D‐succinylase (DSA) and N‐succinylamino acid racemase (NSAR, EC 4.2.1.113). The DSA from Cupriavidus sp. P4‐10‐C, which hydrolyzes N‐succinyl‐D‐amino acids enantioselectively to their corresponding D‐amino acids, was identified for the first time by screening soil microorganisms. Subsequently, the DSA gene was cloned and overexpressed in Escherichia coli. DSA was shown to comprise two subunits with molecular masses of 26 kDa and 60 kDa. Additionally, the NSAR gene from Geobacillus stearothermphilus NCA1503, which racemizes N‐succinylamino acids, was also cloned and overexpressed in E. coli. The highly purified DSA and NSAR prepared from each recombinant E. coli were characterized and used for D‐amino acid synthesis. A one‐pot enzymatic method converted 100 mM N‐succinyl‐dl‐phenylalanine to D‐phenylalanine in 91.1% conversion with 86.7% ee. This novel enzymatic method may be useful for the industrial production of many D‐amino acids.magnified image
Silver‐Catalyzed Intramolecular C‐2 Selective Acylation of Indoles with Aldehydes: An Atom‐Economical Entry to Indole‐Indolone Scaffolds
Authors: Wang Xiaoxia , Li Zhongfeng , Cao Shengli , Rao Honghua 
Published: June 2016

AbstractA direct annulation reaction of N‐(2‐formylaryl)indoles has been developed, which can provide a new entry to biologically and medicinally important indole‐indolone scaffolds via a silver‐catalyzed direct oxidative coupling between aldehyde CH and sp2 CH bonds for the first time. Remarkably, this strategy displayed excellent functional group compatibilities, thereby suggesting its wide potential for applications in developing and synthesizing new drug‐like compounds containing indole‐indolone frameworks.magnified image
Copper‐Mediated 1,2‐Difunctionalization of Styrenes with Sodium Arylsulfinates and tert‐Butyl Nitrite: Facile Access to α‐Sulfonylethanone Oximes
Authors: Yang Ji , Liu Yan‐Yun , Song Ren‐Jie , Peng Zhi‐Hong , Li Jin‐Heng 
Published: June 2016

AbstractA new copper‐mediated synthesis of α‐sulfonylethanone oximes from styrenes, sodium arylsulfinates and tert‐butyl nitrite (t‐BuONO; TBN) is presented. This intermolecular three‐component method enables the one‐step formation of CN and CS bonds under mild conditions, and represents a new, straightforward approach to α‐sulfonylethanone oximes.magnified image
Nickel(II)‐Mediated Regioselective CH Monoiodination of Arenes and Heteroarenes by using Molecular Iodine
Authors: Khan Bhuttu , Kant Ruchir , Koley Dipankar 
Published: June 2016

AbstractThe 8‐aminoquinoline‐directed, nickel(II)‐mediated ortho‐iodination of benzamides using molecular iodine has been developed. The process is highly regioselective and furnishes only monoiodinated products. A broad range of arenes and heteroarenes with diverse functional groups provided monoiodinated products in good to excellent yields.magnified image