bluuebunny/crossref_metadata_2025_split huggingface dataset:
Back to basics: can unstructured camping promote wellbeing?
Authors: Morrow Rosie , Rodriguez Alison , King Nigel 
Published: March 2017

Purpose
The purpose of this paper is to explore the perceived wellbeing benefits of the unstructured camping experience for young adults.

Design/methodology/approach
This is a cross-sectional descriptive phenomenological study. Young adults between the ages of 21 and 30 years with recent experiences of camping were invited to participate in the study. A descriptive phenomenological approach was taken, involving photograph-guided semi-structured interviews and Colaizzi’s seven-stage analysis framework. Ethical approval was granted by the university where the study was managed.

Findings
Four female participants were interviewed; each interview lasted approximately 60 minutes in duration. Unstructured camping holidays were perceived to heighten general perceptions of health and wellbeing. Five themes emerged: “Getting away”, “Appreciation of the Natural Environment”, “Relationship Maintenance”, “Tranquility and Relaxation” and “Freedom and Adventure/Exploration”. The unstructured nature of the activity encouraged participant’s freewill to appreciate the natural environment and to engage in physical activity. Escape from everyday stressors to a tranquil environment provided the space and time to think and talk, relax and be active.

Originality/value
Green care initiatives could use the unstructured camping experience, or what the authors have framed as the “back to basics” model of camping, as a tool to promote general health and wellbeing in clinical and non-clinical young adult populations. Further research is needed to substantiate the evidence base, especially to probe further around the benefits of the spontaneity of the “back to basics” camping experience, in contrast to the structured group camp experiences the authors advocate in the UK and overseas for children’s leisure or health purposes.
Integrating lipid storage into general representations of fish energetics
Authors: Martin Benjamin T. , Heintz Ron , Danner Eric M. , Nisbet Roger M. 
Published: March 2017

SummaryFish, even of the same species, can exhibit substantial variation in energy density (energy per unit wet weight). Most of this variation is due to differences in the amount of storage lipids. In addition to their importance as energy reserves for reproduction and for survival during unfavourable conditions, the accumulation of lipids represents a large energetic flux for many species, so figuring out how this energy flux is integrated with other major energy fluxes (growth, reproduction) is critical for any general theory of organismal energetics.Here, we synthesize data from a wide range of fish species and identify patterns of intraspecific variation in energy storage, and use these patterns to formulate a general model of energy allocation between growth, lipid storage and reproduction in fishes.From the compiled data we identified two patterns: (1) energy density increases with body size during the juvenile period, but is invariant with body size within the adult size range for most species, and (2) energy density changes across seasons, with depletion over winter, but increases fastest in periods of transition between favourable and unfavourable conditions for growth (i.e. fall).Based on these patterns we proposeDEBlipid, a simple, general model of energy allocation that is closely related to a simplified version of Dynamic Energy Budget theory,DEBkiss. The crux of the model is that assimilated energy is partitioned, with κ fraction of energy allocated to pay maintenance costs first, and the surplus allocated to growth, and 1 − κ fraction of assimilated energy is allocated to accumulating storage lipids during the juvenile phase, and later to reproduction as adults. This mechanism, in addition to capturing the two patterns that motivated the model, was able to predict lipid dynamics in a novel context, the migration of anadromous fish from low‐food freshwater to high‐food marine environments. Furthermore, the model was used to explain intra and interspecific variation in reproductive output based on patterns of lipid accumulation as juveniles.Our results suggest that many seemingly complex, adaptive energy allocation strategies in response to ontogeny, seasonality and habitat quality can emerge from a simple physiological heuristic.
Co‐constructing family therapy in the Asian Chinese family diasporas of mainland China, Malaysia, Macau, Singapore and Taiwan
Authors: Sim Timothy , Yi Fang Xiao , Chan Simon , Teik Cheok Loy Johnben , Sng Sharon , Lo Rebecca , Chao Wentao , Singh Reenee 
Published: March 2017

Asian Chinese families are experiencing constant changes. While commonly known cultural themes such as ‘face’, ‘hierarchy’, ‘harmony’ and ‘filial piety’ are useful references and important caveats in clinical settings, they are most useful when the context of larger socio‐economic and political developments of recent decades is taken into account. This article is co‐authored by seven experienced Asian therapists from China, Hong Kong, Macau, Malaysia, Singapore, Taiwan and the United Kingdom. They share their insights into working with Chinese families in Asia. In addition to considering cultural dimensions, the authors attempt to consolidate the understanding of Asian Chinese families by focusing on the effects of socio‐economic and political development. Other than focusing on the unique characteristics and challenges of working with Chinese families in their region, they highlight the most useful therapeutic stances and approaches when working with Asian Chinese families.Practitioner points

Be mindful that changing family structures affect family dynamics, childcentric values and work‐life balance.
Chinese families expect to receive advice and instruction. Therapists need to be direct and authoritative where appropriate to avoid causing dissatisfaction
Chinese families can be helped to negotiate their emerging needs for the differentiation of self
A possible therapeutic option is use of self and the ability to embrace uncertainty
Digital atmospheres: affective practices of care in Elefriends
Authors: Tucker Ian M. , Goodings Lewis 
Published: March 2017

AbstractThis article develops the concept of digital atmosphere to analyse the affective power of social media to shape practices of care and support for people living with mental distress. Using contemporary accounts of affective atmospheres, the article focuses on feelings of distress, support and care that unfold through digital atmospheres. The power of social media intersects with people's support and care‐seeking practices in multiple ways and not in a straightforward model of ‘accessing or providing support’. Indeed, we find that the caring relations developed through social media often need to be cared for themselves. The article draws on online and interview data from a larger project investigating how practices of care and support are (re)configured in the mental health‐related social media site Elefriends. Users have to negotiate the disruption of moving support online, as well as the possibility of becoming subject to a fragility in care, in which caring for oneself becomes bound up in the ambiguities of caring for others. We argue that understanding how experiences of distress are shaped by social media is essential for understanding the implications of the increased digitisation of mental healthcare.
Phenolic Fractions from Muscadine Grape “Noble” Pomace can Inhibit Breast Cancer Cell MDA‐MB‐231 Better than those from European Grape “Cabernet Sauvignon” and Induce S‐Phase Arrest and Apoptosis
Authors: Luo Jianming , Wei Zheng , Zhang Shengyu , Peng Xichun , Huang Yu , Zhang Yali , Lu Jiang 
Published: March 2017

AbstractTons of grape pomace which still contained a rich amount of plant polyphenols, is discarded after winemaking. Plant polyphenols have multi‐functional activities for human body. In this study, polyphenols of pomaces from Muscadinia rotundifolia “Noble” and Vitis vinifera “Cabernet Sauvignon” were extracted and fractionated, and then they were analyzed with LC‐MS and the inhibitory effects on breast cancer cells were compared. The inhibition on MDA‐MB‐231 cells of fractions from “Noble” was further evaluated. The results showed that polyphenols from 2 grape pomaces could be separated into 3 fractions, and ellagic acid and/or ellagitannins were only detected in fractions from “Noble” pomace. All 3 fractions from “Noble” pomace inhibited MDA‐MB‐231 better than MCF‐7. But fraction 2 from “Cabernet Sauvignon” inhibited MCF‐7 better while fraction 1 and fraction 3 inhibited both 2 cells similarly. Moreover, the fractions from “Noble” pomace rather than “Cabernet Sauvignon” can inhibit MDA‐MB‐231 better. Finally, fractions from “Noble” pomace can induce S‐phase arrest and apoptosis on MDA‐MB‐231. These findings suggested the extracts from grape pomace especially those from “Noble,” are potential to be utilized as health beneficial products or even anti‐breast cancer agents.
Improved disease activity with fosdagrocorat (PF‐04171327), a partial agonist of the glucocorticoid receptor, in patients with rheumatoid arthritis: a Phase 2 randomized study
Authors: Stock Thomas , Fleishaker Dona , Wang Xin , Mukherjee Arnab , Mebus Charles 
Published: March 2017

AbstractAimTo assess efficacy and safety of fosdagrocorat (PF‐04171327), a potential dissociated agonist of the glucocorticoid receptor, in rheumatoid arthritis (RA) patients.MethodsThis multicenter, double‐blind, parallel‐group, active‐ and placebo‐controlled Phase 2 study (NCT00938587) randomized 86 patients (1 : 1 : 1 : 1) to receive fosdagrocorat 10 mg, fosdagrocorat 25 mg, prednisone 5 mg or placebo, all with stable background methotrexate therapy. The primary outcome was change from baseline in Disease Activity Score of 28 joints (DAS28‐4[C‐reactive protein (CRP)]) after 2 weeks of treatment. Secondary outcomes included American College of Rheumatology (ACR) response rates, change from baseline in ACR core components and Health Assessment Questionnaire Disability Index.ResultsAt week 2, improvements from baseline in DAS28‐4(CRP) with fosdagrocorat 10 and 25 mg, prednisone 5 mg and placebo were −1.69, −2.22, −1.17 and −0.96, respectively, and were statistically significantly greater for both fosdagrocorat doses versus placebo (P < 0.05) and for fosdagrocorat 25 mg versus prednisone 5 mg (P < 0.001). The effects of fosdagrocorat on secondary outcomes were generally consistent with those observed for the primary outcome. Adverse events (AEs) were reported for eight (38%), three (14%), four (19%) and 12 (55%) patients treated with fosdagrocorat 10 and 25 mg, prednisone 5 mg and placebo, respectively. Most AEs were mild in severity. Four patients discontinued treatment due to AEs (fosdagrocorat 10 mg, n = 2; placebo, n = 2). There were no serious AEs.ConclusionFosdagrocorat 10 and 25 mg demonstrated efficacy in improving signs and symptoms in RA patients, with manageable AEs. Additional studies are needed to assess the longer‐term safety and efficacy of fosdagrocorat.
Clinical characteristics of multifocal osteonecrosis in Korean patients with rheumatic disease
Authors: Jeong Hye‐Jin , Kim Dam , Cho Soo‐Kyung , Kim Yeesuk , Bae Sang‐Cheol , Sung Yoon‐Kyoung 
Published: March 2017

AbstractAimOsteonecrosis (ON), also known as avascular necrosis, is an important cause of physical disability in rheumatic disease. When this condition affects multiple structures, disability is increased. The purpose of this study was to describe the clinical characteristics of Korean patients with multifocal ON associated with rheumatic disease and to compare them with those of previously reported cases.MethodsWe reviewed the clinical characteristics of eight Korean patients with multifocal ON, defined by the involvement of three or more anatomic sites, associated with rheumatic disease in a single referral academic hospital, and compared them with those of 19 similar cases previously reported in the literature.ResultsAll eight patients were female, with median age of 26 years. All had underlying systemic lupus erythematosus (SLE) and had been using corticosteroids. The most common site affected by ON was the knee joint. However, in contrast to our patients, the previous reported cases had other rheumatic diseases such as myositis, scleroderma and antiphospholipid syndrome. In comparison between Korean multifocal ON patients with SLE and those of previous reports, shoulder joint involvement was higher in previous reports. Common features in patients from both groups were knee joint involvement and prevalent use of corticosteroids.ConclusionOur findings indicate that multifocal ON is common in young SLE patients who have been using corticosteroids and the most commonly involved site is the knee.
Long‐term follow‐up study of community‐based patients receiving XR‐NTX for opioid use disorders
Authors: Williams Arthur Robin , Barbieri Vincent , Mishlen Kaitlyn , Levin Frances R. , Nunes Edward V. , Mariani John J. , Bisaga Adam 
Published: March 2017

Background and ObjectivesExtended‐release naltrexone (XR‐NTX) is FDA‐approved to prevent relapse in patients with Opioid Use Disorder. However little is known about long‐term use among community‐based outpatients.MethodsRetrospective chart review and long‐term follow‐up survey among individuals (N = 168) who entered an outpatient XR‐NTX trial between 2011 and 2015, during which participants were offered three monthly injections of XR‐NTX at no cost. The survey consisted of 35 questions covering a total of four domains: (1) substance use; (2) treatment continuation; (3) barriers; and (4) attitudes.ResultsFifty‐seven respondents were successfully surveyed, including 50% of those initially receiving all three XR‐NTX injections (“study completers”) in the parent study. Study completion was associated with superior outcomes and less likely relapse (defined as daily use), with a much greater time to relapse despite higher rates of concurrent non‐opioid substance use. However the majority of participants discontinued treatment with XR‐NTX at study completion, largely due to attitudes of “feeling cured” and “wanting to do it on my own” rather than external barriers such as cost or side effects.ConclusionPatients who initiate treatment with XR‐NTX might benefit from anticipatory guidance and motivational techniques to encourage long‐term adherence as many will experience internal barriers to continuation. Our findings are reassuring that few patients experience side effects or adverse events complicating the effectiveness or safety of long‐term use of XR‐NTX.Scientific SignificanceAmong outpatients who successfully receive 3 monthly XR‐NTX injections, many will prematurely discontinue treatment due to internal attitudes, such as “feeling cured.” (Am J Addict 2017;26:319–325)
Seat belt repositioning and use of vehicle seat cushions is increased among older drivers aged 75 years and older with morbidities
Authors: Brown Julie , Coxon Kristy , Fong Cameron , Clarke Elizabeth , Rogers Kris , Keay Lisa 
Published: March 2017

ObjectiveGood seat belt fit and positioning is important for crash protection. Older drivers experience problems in achieving good seat belt fit and often reposition seat belts and/or use seat cushions. Comfort influences these behaviours. This work examines the impact of functional morbidities on belt positioning and accessory use and whether comfort mediates this relationshipMethodsMediation analysis was used to examine the relationship between morbidities affecting physical function, comfort, belt repositions and seat cushion use among 380 drivers aged 75 years and older.ResultsMusculoskeletal morbidities increase the likelihood of seat belt repositioning (OR 1.37, 95% CI 1.12–1.67) and comfort partially mediates this relationship (P = 0.03). Morbidities of any type also increase the likelihood of seat cushion use (OR 1.15 95% CI 1.04–1.27), but comfort plays no role in this relationship (P = 0.87).ConclusionGreater awareness among older drivers is needed, to ensure behavioural modifications do not impair their crash protection.
Randomised controlled trial demonstrates that fermented infant formula with short‐chain galacto‐oligosaccharides and long‐chain fructo‐oligosaccharides reduces the incidence of infantile colic
Authors: Vandenplas Yvan , Ludwig Thomas , Bouritius Hetty , Alliet Philippe , Forde Derek , Peeters Stefaan , Huet Frederic , Hourihane Jonathan 
Published: March 2017

AbstractAimWe examined the effects on gastrointestinal (GI) tolerance of a novel infant formula that combined specific fermented formula (FERM) with short‐chain galacto‐oligosaccharides and long‐chain fructo‐oligosaccharides (scGOS/lcFOS), with a 9:1 ratio and concentration of 0.8 g/100 mL.MethodsThis prospective, double‐blind, randomised, controlled trial comprised 432 healthy, term infants aged 0–28 days whose parents decided to not start, or discontinued, breastfeeding. Infant formula with scGOS/lcFOS+50%FERM, scGOS/lcFOS+15%FERM, 50%FERM and scGOS/lcFOS were tested. Parents completed standardised seven‐day diaries on GI symptoms, crying, sleeping and stool characteristics each month until the infants were 17 weeks.ResultsAll the formulas were well tolerated. At four weeks, the overall incidence of infantile colic was significantly lower (8%) with scGOS/lcFOS+50%FERM than scGOS/lcFOS (20%, p = 0.034) or 50%FERM (20%, p = 0.036). Longitudinal modelling showed that scGOS/lcFOS+50%FERM‐fed infants also displayed a persistently lower daily crying duration and showed a consistent stool‐softening effect than infants who received formula without scGOS/lcFOS.ConclusionThe combination of fermented formula with scGOS/lcFOS was well tolerated and showed a lower overall crying time, a lower incidence of infantile colic and a stool‐softening effect in healthy term infants. These findings suggest for the first time that a specific infant formula has a preventive effect on infantile colic in formula‐fed infants.
Diversity of seeds captured by interception exceeds diversity of seeds deposited in traps
Authors: Stone Judy L. , Malloy Ryan , Murray Greg 
Published: March 2017

AbstractSeed dispersal, a key process in terrestrial landscapes, is increasingly important in the face of habitat fragmentation and global climate change. Seed dispersal is also notoriously difficult to characterize, especially in species rich and spatially complex tropical forests. We contrasted assemblages of biotically dispersed seeds collected from four sites using two methods: deposition into seed traps and interception by the capture of frugivorous birds. We also compared seed deposition and interception with local fruit production. Species accumulation curves for seeds deposited in seed traps began to level off sooner than curves for seeds collected from birds captured in mist nets, and extrapolation showed significantly greater estimated species richness for seeds collected from birds than for those deposited in traps. Assemblages from birds and from traps at each site were quite different, with an abundance‐based similarity index of 0.64; this dissimilarity increases if bat‐dispersed seeds are included in the analysis. Common bird‐dispersed species were retrieved from both mist‐netted birds and from seed traps, but numerous locally fruiting understory species were recovered only from birds. We conclude that the sampling of seeds carried by birds provides a valuable complement to other methods of studying seed dispersal in species‐rich tropical forests by revealing relationships between specific dispersers and their seed plants and by creating a more complete account of species diversity of seeds being transported at a given site.
Anti‐N‐methyl‐d‐aspartate receptor encephalitis in Māori and Pacific Island children in New Zealand
Authors: Jones Hannah F , Mohammad Shekeeb S , Reed Peter W , Dunn Paul P J , Steele Richard H , Dale Russell C , Sharpe Cynthia 
Published: March 2017

AimTo investigate the incidence and severity of anti‐N‐methyl‐d‐aspartate (anti‐NMDA) receptor encephalitis in children from New Zealand.MethodA retrospective case series was undertaken of all children (≤18y) diagnosed with anti‐NMDA receptor encephalitis from January 2008 to October 2015.ResultsSixteen patients were identified with anti‐NMDA receptor antibodies in the cerebrospinal fluid, three of whom had an associated teratoma. Fifteen children had Māori and/or Pacific Island ancestry. The incidence of anti‐NMDA receptor encephalitis in Māori children was 3.4 per million children per year (95% confidence interval [CI] 1.4–7.0) and the incidence in Pacific children was 10.0 per million children per year (95% CI 4.3–19.8) compared with 0.2 per million children per year (95% CI 0.0–1.0) in children without Māori or Pacific Island ancestry. Sixty‐seven per cent of children had a good outcome (modified Rankin Score ≤2) at 2 years’ follow‐up. This compares unfavourably with other cohorts despite a shorter median time to first‐line immunotherapy (13d; range 4–89) and a higher proportion of children being treated with second‐line therapy (50%).InterpretationMāori and Pacific Island children have a higher incidence of anti‐NMDA receptor encephalitis and possibly a more severe phenotype. These data suggest a genetic predisposition to anti‐NMDA receptor encephalitis in these populations.
Recruitment and Retention of Low‐SES Ethnic Minority Couples in Intervention Research at the Transition to Parenthood
Authors: Baucom Katherine J. W. , Chen Xiao S. , Perry Nicholas S. , Revolorio Kaddy Y. , Reina Astrid , Christensen Andrew 
Published: March 2017

Low‐SES couples have limited resources to manage the chronic and acute stressors with which they are disproportionately faced. Although these couples are at greater risk for negative individual and relationship outcomes, evaluations of the impact of couple relationship education (CRE) in low‐SES couples have been plagued by methodological problems, most notably challenges associated with recruitment and retention. We review the literature on challenges couples face associated with low‐SES, as well as on recruitment, retention, and CRE in low‐SES, ethnic minority populations. We illustrate some of these challenges in a case study of CRE for low‐SES couples transitioning to parenthood. In this pilot study, 21 couples were recruited from a community health clinic and randomized to either an experimental treatment condition (EXP; N = 11) or a treatment‐as‐usual control condition (TAU; N = 10). This study sought to mitigate documented challenges with recruitment and retention: We leveraged community partnerships, attempted to build and maintain strong relationships with study participants, provided incentives for assessments as well as intervention meetings, and attempted to reduce potential barriers to enrollment and retention. Nonetheless, we had low rates of recruitment and retention. We integrate these findings and experiences with our review of previous work in this area. We make recommendations for future CRE research and practice that have potential implications for public policy in this area.