bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hydrothermal iron flux variability following rapid sea level changes
Authors: Middleton Jennifer L. , Langmuir Charles H. , Mukhopadhyay Sujoy , McManus Jerry F. , Mitrovica Jerry X. 
Published: April 2016

AbstractSea level changes associated with Pleistocene glacial cycles have been hypothesized to modulate melt production and hydrothermal activity at ocean ridges, yet little is known about fluctuations in hydrothermal circulation on time scales longer than a few millennia. We present a high‐resolution record of hydrothermal activity over the past 50 ka using elemental flux data from a new sediment core from the Mir zone of the TAG hydrothermal field at 26°N on the Mid‐Atlantic Ridge. Mir sediments reveal sixfold to eightfold increases in hydrothermal iron and copper deposition during the Last Glacial Maximum, followed by a rapid decline during the sea level rise associated with deglaciation. Our results, along with previous observations from Pacific and Atlantic spreading centers, indicate that rapid sea level changes influence hydrothermal output on mid‐ocean ridges. Thus, climate variability may discretize volcanic processing of the solid Earth on millennial time scales and subsequently stimulate variability in biogeochemical interactions with volcanic systems.
Non‐Radiative Energy Transfer Mediated by Hybrid Light‐Matter States
Authors: Zhong Xiaolan , Chervy Thibault , Wang Shaojun , George Jino , Thomas Anoop , Hutchison James A. , Devaux Eloise , Genet Cyriaque , Ebbesen Thomas W. 
Published: April 2016

AbstractWe present direct evidence of enhanced non‐radiative energy transfer between two J‐aggregated cyanine dyes strongly coupled to the vacuum field of a cavity. Excitation spectroscopy and femtosecond pump–probe measurements show that the energy transfer is highly efficient when both the donor and acceptor form light‐matter hybrid states with the vacuum field. The rate of energy transfer is increased by a factor of seven under those conditions as compared to the normal situation outside the cavity, with a corresponding effect on the energy transfer efficiency. The delocalized hybrid states connect the donor and acceptor molecules and clearly play the role of a bridge to enhance the rate of energy transfer. This finding has fundamental implications for coherent energy transport and light‐energy harvesting.
Identifizierung des Schlüsselenzyms der Roseoflavinbiosynthese
Authors: Schwarz Julia , Konjik Valentino , Jankowitsch Frank , Sandhoff Roger , Mack Matthias 
Published: April 2016

AbstractDie Bakterienarten Streptomyces davawensis und Streptomyces cinnabarinus produzieren Roseoflavin, das einzige bekannte natürliche Analogon von Riboflavin (Vitamin B2) mit antibiotischer Wirkung. Roseoflavin kann als natürlicher Antimetabolit bezeichnet werden und soll aus Riboflavin über das Schlüsselintermediat 8‐Demethyl‐8‐aminoriboflavin (AF) synthetisiert werden. Der ortsspezifische Austausch einer Methylgruppe des Dimethylbenzolrings von Riboflavin gegen eine Aminogruppe (der zu AF führt) ist mechanistisch schwierig. Der Biosyntheseweg von Riboflavin zu AF war unklar, und das/die zugehörige/n Enzym/e war/en unbekannt. Systematische Gendeletions‐ und ‐expressionsexperimente sowie biochemische Analysen zeigten jetzt, dass das vom Gen BN159_7989 aus S. davawensis kodierte Enzym mehrere chemischer Reaktionen katalysieren kann: Ausgehend von Riboflavin‐5′‐phosphat bildet BN159_7989 8‐Demethyl‐8‐aminoriboflavin‐5′‐phosphat.
Self‐Assembled Amphiphilic Water Oxidation Catalysts: Control of O−O Bond Formation Pathways by Different Aggregation Patterns
Authors: Yang Bing , Jiang Xin , Guo Qing , Lei Tao , Zhang Li‐Ping , Chen Bin , Tung Chen‐Ho , Wu Li‐Zhu 
Published: April 2016

AbstractThe oxidation of water to molecular oxygen is the key step to realize water splitting from both biological and chemical perspective. In an effort to understand how water oxidation occurs on a molecular level, a large number of molecular catalysts have been synthesized to find an easy access to higher oxidation states as well as their capacity to make O−O bond. However, most of them function in a mixture of organic solvent and water and the O−O bond formation pathway is still a subject of intense debate. Herein, we design the first amphiphilic Ru‐bda (H2bda=2,2′‐bipyridine‐6,6′‐dicarboxylic acid) water oxidation catalysts (WOCs) of formula [RuII(bda)(4‐OTEG‐pyridine)2] (1, OTEG=OCH2CH2OCH2CH2OCH3) and [RuII(bda)(PySO3Na)2] (2, PySO3−=pyridine‐3‐sulfonate), which possess good solubility in water. Dynamic light scattering (DLS), scanning electron microscope (SEM), critical aggregation concentration (CAC) experiments and product analysis demonstrate that they enable to self‐assemble in water and form the O−O bond through different routes even though they have the same bda2− backbone. This work illustrates for the first time that the O−O bond formation pathway can be regulated by the interaction of ancillary ligands at supramolecular level.
Rhodium‐Catalyzed Intramolecular C−H Silylation by Silacyclobutanes
Authors: Zhang Qing‐Wei , An Kun , Liu Li‐Chuan , Guo Shuangxi , Jiang Chenran , Guo Huifang , He Wei 
Published: April 2016

AbstractSilacyclobutane was discovered to be an efficient C−H bond silylation reagent. Under the catalysis of RhI/TMS‐segphos, silacyclobutane undergoes sequential C−Si/C−H bond activations, affording a series of π‐conjugated siloles in high yields and regioselectivities. The catalytic cycle was proposed to involve a rarely documented endocyclic β‐hydride elimination of five‐membered metallacycles, which after reductive elimination gave rise to a Si−RhI species that is capable of C−H activation.
Parietal Bone Thickness and Vascular Diameters in Adult Modern Humans: A Survey on Cranial Remains
Authors: Eisová Stanislava , Rangel de Lázaro Gizéh , Píšová Hana , Pereira‐Pedro Sofia , Bruner Emiliano 
Published: April 2016

ABSTRACTCranial bone thickness varies among modern humans, and many factors influencing this variability remain unclear. Growth hormones and physical activity are thought to influence the vault thickness. Considering that both systemic factors and energy supply influence the vascular system, and taking into account the structural and biomechanical interaction between endocranial vessels and vault bones, in this study we evaluate the correlation between vascular and bone diameters. In particular, we tested the relationship between the thickness of the parietal bone (which is characterized, in modern humans, by a complex vascular network) and the lumen size of the middle meningeal and diploic vessels, in adult modern humans. Our results show no patent correlation between the thickness of parietal bone and the size of the main vascular channels. Values and distributions of the branching patterns, as well as anatomical relationships between vessels and bones, are also described in order to provide information concerning the arrangement of the endocranial vascular morphology. This information is relevant in both evolutionary and medical contexts. Anat Rec, 299:888–896, 2016. © 2016 Wiley Periodicals, Inc.
Organotypic slice cultures of human gastric and esophagogastric junction cancer
Authors: Koerfer Justus , Kallendrusch Sonja , Merz Felicitas , Wittekind Christian , Kubick Christoph , Kassahun Woubet T. , Schumacher Guido , Moebius Christian , Gaßler Nikolaus , Schopow Nikolas , Geister Daniela , Wiechmann Volker , Weimann Arved , Eckmann Christian , Aigner Achim , Bechmann Ingo , Lordick Florian 
Published: April 2016

AbstractGastric and esophagogastric junction cancers are heterogeneous and aggressive tumors with an unpredictable response to cytotoxic treatment. New methods allowing for the analysis of drug resistance are needed. Here, we describe a novel technique by which human tumor specimens can be cultured ex vivo, preserving parts of the natural cancer microenvironment. Using a tissue chopper, fresh surgical tissue samples were cut in 400 μm slices and cultivated in 6‐well plates for up to 6 days. The slices were processed for routine histopathology and immunohistochemistry. Cytokeratin stains (CK8, AE1/3) were applied for determining tumor cellularity, Ki‐67 for proliferation, and cleaved caspase‐3 staining for apoptosis. The slices were analyzed under naive conditions and following 2–4 days in vitro exposure to 5‐FU and cisplatin. The slice culture technology allowed for a good preservation of tissue morphology and tumor cell integrity during the culture period. After chemotherapy exposure, a loss of tumor cellularity and an increase in apoptosis were observed. Drug sensitivity of the tumors could be assessed. Organotypic slice cultures of gastric and esophagogastric junction cancers were successfully established. Cytotoxic drug effects could be monitored. They may be used to examine mechanisms of drug resistance in human tissue and may provide a unique and powerful ex vivo platform for the prediction of treatment response.
Gold Nanoparticles Supported on Fibrous Silica Nanospheres (KCC‐1) as Efficient Heterogeneous Catalysts for CO Oxidation
Authors: Qureshi Ziyauddin S. , Sarawade Pradip B. , Hussain Irshad , Zhu Haibo , Al‐Johani Hind , Anjum Dalaver H. , Hedhili Mohamed Nejib , Maity Niladri , D'Elia Valerio , Basset Jean‐Marie 
Published: April 2016

AbstractGold nanoparticles (Au NPs) of different sizes were supported on fibrous silica nanospheres (KCC‐1) by various methods. The size and the location of the Au NPs on the support were found to depend on the preparation method. The KCC‐1‐supported Au NPs were thoroughly characterized by using HR‐TEM, XRD, X‐ray photoelectron spectroscopy, UV, and Brunauer–Emmett–Teller surface area measurements and were applied in catalysis for the oxidation of CO. The catalytic performance is discussed in relation to the morphological properties of KCC‐1.
Enzyme‐Catalyzed Carbonyl Olefination by the E. coli Protein YfeX in the Absence of Phosphines
Authors: Weissenborn Martin J. , Löw Sebastian A. , Borlinghaus Niels , Kuhn Miriam , Kummer Stefanie , Rami Fabian , Plietker Bernd , Hauer Bernhard 
Published: April 2016

AbstractThe Wittig‐type carbonyl olefination reaction has no biocatalytic equivalent. To build complex molecular scaffolds, however, C−C bond‐forming reactions are pivotal for biobased economy and synthetic biology. The heme‐containing E. coli protein YfeX was found to catalyze carbonyl olefination by reaction of benzaldehyde with ethyl diazoacetate under aerobic conditions in the absence of a triphenylphosphine oxophile. The reaction was performed in whole cells and showed a product formation of 440 mg L−1 in 1 h. It was, moreover, shown that the reaction could be performed under Wittig‐analogue conditions in the presence of triphenylphosphine or triphenylarsine.
Glycomimetics Targeting Glycosyltransferases: Synthetic, Computational and Structural Studies of Less‐Polar Conjugates
Authors: Ghirardello Mattia , de las Rivas Matilde , Lacetera Alessandra , Delso Ignacio , Lira‐Navarrete Erandi , Tejero Tomás , Martín‐Santamaría Sonsoles , Hurtado‐Guerrero Ramón , Merino Pedro 
Published: April 2016

AbstractThe Leloir donors are nucleotide sugars essential for a variety of glycosyltransferases (GTs) involved in the transfer of a carbohydrate to an acceptor substrate, typically a protein or an oligosaccharide. A series of less‐polar nucleotide sugar analogues derived from uridine have been prepared by replacing one phosphate unit with an alkyl chain. The methodology is based on the radical hydrophosphonylation of alkenes, which allows coupling of allyl glycosyl compounds with a phosphate unit suitable for conjugation to uridine. Two of these compounds, the GalNAc and galactose derivatives, were further tested on a model GT, such as GalNAc‐T2 (an important GT widely distributed in human tissues), to probe that both compounds bound in the medium–high micromolar range. The crystal structure of GalNAc‐T2 with the galactose derivative traps the enzyme in an inactive form; this suggests that compounds only containing the β‐phosphate could be efficient ligands for the enzyme. Computational studies with GalNAc‐T2 corroborate these findings and provide further insights into the mechanism of the catalytic cycle of this family of enzymes.
Enantiopure Functional Molecular Motors Obtained by a Switchable Chiral‐Resolution Process
Authors: van Leeuwen Thomas , Gan Jefri , Kistemaker Jos C. M. , Pizzolato Stefano F. , Chang Mu‐Chieh , Feringa Ben L. 
Published: April 2016

AbstractMolecular switches, rotors, and motors play an important role in the development of nano‐machines and devices, as well as responsive and adaptive functional materials. For unidirectional rotors based on chiral overcrowded alkenes, their stereochemical homogeneity is of crucial importance. Herein, a method to obtain new and functionalizable overcrowded alkenes in enantiopure form is presented. The procedure involves a short synthesis of three steps and a solvent‐switchable chiral resolution by using a readily available resolving agent. X‐ray crystallography revealed the mode of binding of the motor with the resolving agent, as well as the absolute configuration of the motor. 1H NMR and UV/Vis spectroscopy techniques were used to determine the dynamic behavior of this molecular motor. This method provides rapid access to ample amounts of enantiopure molecular motors, which will greatly facilitate the further development of responsive molecular systems based on chiral overcrowded alkenes.
ChemInform Abstract: ON THE PHASE CHROMIUM TELLURIDE (CRTE3)
Authors: KLEPP K. O. , IPSER H. 
Published: April 2016

AbstractEin Haltepunkt bei 718 K in der DTA‐Kurve von Cr‐Te mit 75‐95 Atom‐% Te und ein zusätzlicher bei 753 K für 72.5 Atom‐% Te beweisen die Existenz einer Phase CrTe3, die sich bei 753 K peritektisch zersetzt.
ChemInform Abstract: DIRECT REMOTE OXIDATION OF ACYCLIC ACETATES, MACROCYCLIC ACETATES, AND MACROLIDES
Authors: EIGENDORF G. K. , MA C.‐L. , MONEY T. 
Published: April 2016

AbstractDie direkte Oxidation der Titelverbindungen (I), (IIIa) und (V) liefert Gemische isomerer Monoketone (II) (Oxidation am C‐2 bis C‐6 fmdet kaum statt), (IV) ((IIIb) und (IIIc) reagieren ähnlich) bzw. (VI).
ChemInform Abstract: OPTICAL ACTIVITY AND ABSOLUTE CONFIGURATION OF 5,6,11,12‐TETRAHYDRO‐2,3,8,9‐TETRAMETHOXY‐5,11‐METHANODIBENZO(A,E)CYCLOOCTATETRAENE
Authors: OGURA F. , NAKAO A. , NAKAGAWA M. 
Published: April 2016

AbstractUmsetzung des Nitrils (I) mit CH2I2 ergibt das Glutarsäuredinitril (IIa) (racemische/meso‐Form), dessen Hydrolyseprodukt, die Dicarbonsäure(+/‐)‐(IIb), zu dem Diketon(+/‐)‐(IIIa) cyclisiert wird.
ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL SCREENING OF 1,2,3‐TRIAZOLE DERIVATIVES OF NAPHTHALENE, QUINOLINE, PYRIDINE
Authors: LIVI O. , FERRARINI P. L. , TONETTI I. , SMALDONE F. , ZEFOLA G. 
Published: April 2016

AbstractDurch Umsetzung des Aminonaphthalins (I) mit Natriumnitrit und Natriumazid bzw. des Chlorchinolins (II) und des Chlorpyridins (V) mit Natriumazid erhält man die Azide (II), (IV) und (VI).
ChemInform Abstract: SYNTHESIS AND PHOTOBIOLOGICAL PROPERTIES OF 4,8‐DIMETHYL‐5′‐CARBOXYPSORALEN: A MAJOR METABOLITE OF 4,5′,8‐TRIMETHYLPSORALEN
Authors: MARCIANI S. , GUIOTTO A. , RODIGHIERO P. , GIA O. , RODIGHIERO G. , PATHAK M. A. 
Published: April 2016

AbstractDas Diphenol (I) reagiert mit Acetessigester (II) zum Cumarin (III).
ChemInform Abstract: BISMUTH(III) METHOXIDES
Authors: GATTOW G. , LINGENFELDER R. 
Published: April 2016

AbstractDurch Umsetzung methanolischer Lösungen von LiOCH3 mit BiCl3 im Molverhältnis 1: l bis 4:1 bei 0 °C werden die Methoxide (I) mit nahezu quantitativer Ausb. erhalten.
ChemInform Abstract: SOME UNUSUAL METHYLATIONS AND ARYLATIONS OF PLATINUM(II) CHLORIDES BY ORGANOTIN COMPOUNDS. THE CARBON‐13 NMR SPECTRA OF BISARYL(η‐CYCLOOCTA‐1,5‐DIENE)PLATINUM(II) COMPLEXES
Authors: DAWOODI Z. , EABORN C. , PIDCOCK A. 
Published: April 2016

AbstractDer Platin‐cyclooctadienyl‐Komplex (I) reagiert mit Tetramethylzinn (II) unter Substitution eines Chloratoms durch die Methylgruppe.
ChemInform Abstract: THE PREPARATION AND STEREOCHEMISTRY OF 1‐(CHLOROETHYL)‐4‐METHYL‐6,7‐DIMETHOXYISOCHROMAN
Authors: MCCALL J. M. , TENBRINK R. E. , KAMDAR B. V. , CHIDESTER C. 
Published: April 2016

AbstractAus den Carbinol (I) und dem Chlorpropionaldehydacetal (II) entsteht ein Gemisch der Cyclisierungsprodukte (III) und (IV).
ChemInform Abstract: STUDIES ON 1‐ALKYL‐2(1H)‐PYRIDONE DERIVATIVES. XXVII. THE DIELS‐ALDER REACTIONS OF 1‐METHYL‐2(1H)‐PYRIDONE WITH METHYL ACRYLATE AND ACRYLONITRILE
Authors: TOMISAWA H. , HONGO H. , KATO H. , NARAKI T. , FUJITA R. 
Published: April 2016

AbstractDas Pyridon (I) reagiert mit Acrylsäuremethylester (II) in 30%iger Gesamtausbeute zu einem Gemisch der Cycloaddukte (III)‐(V), die sich nicht trennen lassen.
ChemInform Abstract: TOTAL SYNTHESIS OF DL‐HOP ETHER, AN IRIDOID MONOTERPENE
Authors: IMAGAWA T. , MURAI N. , AKIYAMA T. , KAWANISI M. 
Published: April 2016

AbstractAus dem Ester (Ia) wird durch Reduktion mit Lithiumaluminiumhydrid der Alkohol (Ib) erhalten, der zu (Ic) acyliert wird.
ChemInform Abstract: STUDIES OF PYRAZINES. V. PREPARATION OF 2‐ALKYLPYRAZINES FROM ALKYL 2‐PYRAZINYL SULFONES
Authors: KONAKAHARA T. , GOKAN K. , IWAMA M. , TAKAGI Y. 
Published: April 2016

AbstractDie Pyrolyse der 2‐Pyrazinylalkylsulfone (I) führt zu 2‐Alkylpyrazinen (II), Pyrazin (III) und SO2.
ChemInform Abstract: ROTATING DISK AND RING DISK ELECTRODE STUDIES OF TIN IN NEUTRAL PHOSPHATE SOLUTION
Authors: DO DUC H. , TISSOT P. 
Published: April 2016

AbstractDie Auflösungsreaktionen der Sn‐Elektrode V01′ ihrer PHSSiViCTUPE 1388611 Sich durch die Ring‐Scheiben‐Methode charakterisieren.
ChemInform Abstract: AN X‐RAY PHOTOELECTRON SPECTROSCOPY STUDY OF THE PASSIVITY OF AMORPHOUS IRON‐MOLYBDENUM ALLOYS
Authors: HASHIMOTO K. , NAKA M. , ASAMI K. , MASUMOTO T. 
Published: April 2016

AbstractIm Gegensatz zu kristallinen Legierungen ohne Cr auf Fe‐Basis fördert steigender Mo‐Gehalt in amorphen Fe‐Mm‐P‐C‐Legierungen die Passivierung in IN HCI.
ChemInform Abstract: PREPARATION AND CHARACTERIZATION OF (RAC‐5,7,7,12,14,14,‐HEXAMETHYL‐1,4,8,11‐TETRAAZOCYCLOTETRADECANE)COPPER(II) O‐MERCAPTOBENZOATE HYDRATE, (CU(TET B)(O‐SC6H4CO2)).H2O, A COMPLEX WITH A CUN4S (MERCAPTIDE) CHROMOPHORE
Authors: HUGHEY J. L. IV , FAWCETT T. G. , RUDICH S. M. , LALANCETTE R. A. , POTENZA J. A. , SCHUGAR H. J. 
Published: April 2016

AbstractDer in trockener Luft beständige Titelkomplex (I) wird durch Behandlung des aus hydratisiertem Cu(II)‐perchlorat und dem N4‐Makrocyclus bei pH 11 gebildeten kationischen 1:1‐ Komplex mit einem Überschuß des Dinatriumsalzes von o‐Mercaptobenzoesäure synthetisiert.
ChemInform Abstract: METAL BINDING TO FOUR DIFFERENT SITES IN ADENINE LIGANDS. CRYSTAL STRUCTURES OF 2:1 METHYLMERCURY COMPLEXES WITH ADENINE AND 9‐METHYLADENINE
Authors: PRIZANT L. , OLIVIER M. J. , RIVEST R. , BEAUCHAMP A. L. 
Published: April 2016

AbstractAus einer wäßrigen Mischung von 9‐Methyladenin, Methylquecksilberperchlorat und NaOH im Verhältnis l :2: 1 wird der 2:1‐Komplex (I) erhalten.
ChemInform Abstract: SYNTHESIS AND REACTIONS OF 2‐IMINOCYCLOHEXANEDITHIOCARBOXYLIC ACID
Authors: TAKESHIMA T. , YANO A. , FUKADA N. , HIROSE Y. , MURAOKA M. 
Published: April 2016

AbstractAus dem Ammoniumdithiocarboxylat (II), das durch Behandlung von Cyclohexanon (I) mit einem Überschuß an CS2 in wäßrigem Ammoniak entsteht, wird die Titelverbindung (III) mit Essigsäure freigesetzt.
ChemInform Abstract: CHEMISTRY IN HYDROGEN FLUORIDE. 6. OXIDATIVE FLUORINATION OF AROMATIC COMPOUNDS
Authors: FEIRING A. E. 
Published: April 2016

AbstractDie beiden p‐substituierten Toluole (I) reagieren mit verschiedenen Oxidationsmitteln wie Bleidioxid, Nickeldioxid, Co(III)‐acetat, Co(III)‐fluorid, Silber(II)‐ fluorid oder Silber(II)‐oxid in f1.
ChemInform Abstract: REACTIONS OF PHTHALIC ANHYDRIDE WITH 2‐AMINO ALCOHOLS
Authors: WICKS Z. W. JUN. , CHEN G.‐F. 
Published: April 2016

AbstractDie Reaktion zwischen Phthalsäureanhydrid (I) und′ den Aminoalkoholen (II) zu den Folgeprodukten (III) bis (V) wird untersucht.
ChemInform Abstract: DIINDENE (INDENE DIMER): A TRIBOLUMINESCENT COMPOUND
Authors: NOLAND W. E. , LANDUCCI L. L. , DARLING J. C. 
Published: April 2016

AbstractDie z.B. mit Phosphorsäure vorgenommene Dimerisierung von lH‐Inden (Ia) und seinem 3‐Methyl‐Analo‐ ‐gon (Ib) führt zu den beiden Dimeren (II).
ChemInform Abstract: SYNTHESIS OF 7‐FLUOROBENZ(A)ANTHRACENE
Authors: NEWMAN M. S. , LILJE K. C. 
Published: April 2016

AbstractBenz(a)anthracen (Ia) wird zu (Ib) nitriert und nach Reduktion zum Amin (Ic) in das Diazoniumsalz (Id) umgewandelt.
ChemInform Abstract: CONDENSED THIOPHENE RING SYSTEMS. PART 21. 5‐ARYLTHIENO(3,2‐C)PYRAZOLES AND ATTEMPTED PREPARATION OF 5‐ARYLTHIENO(2,3‐C)PYRAZOLES, RESULTING IN A NOVEL THIOPHENE TO PYRROLE TRANSFORMATION
Authors: COLBURN V. M. , IDDON B. , SUSCHITZKY H. , GALLAGHER P. T. 
Published: April 2016

AbstractWährend die reduktive Cyclisierung der Anile (I) ‐ erhältlich aus dem Aldehyd (IX) mit entsprechenden Aminen ‐ mit Triethylphosphit zu den Produkten (IIa) (daneben das (abtrennbare) Aminophosphonat (III)) bzw. (IIb) führt, werden bei gleicher Behandlung aus den (I)‐Isomeren (IV) ‐ analog erhältlich aus dem Aldehyd (XIV) ‐ unerwarteterweise die Cyanpyrrole (V) gebildet (Diskussion des Bildungsmechanismus).
ChemInform Abstract: CYCLOADDITION OF CHIRAL NITRONES. ASYMMETRIC SYNTHESIS OF ISOXAZOLIDINES
Authors: BELZECKI C. , PANFIL I. 
Published: April 2016

AbstractBei der Reaktion mit Phenylisocyanat (II) erhält man aus den Nitronen (I) die Addukte (III), mit Acrylester (IV) erhält man die Addukte (V).
ChemInform Abstract: A PREPARATION OF 3‐AMINO‐4,5‐DIARYL‐1,2,4‐TRIAZOLES
Authors: DAVIDSON J. S. 
Published: April 2016

AbstractThiobenzanilide (I) werden mit Hydrazin‐hydrat zu Benzamidrazonen (II) umgesetzt, die mit Bromcyan zu 3‐Amino‐1 ,2,4‐triazolen (III) cyclisieren.
ChemInform Abstract: GENERAL METHOD FOR THE PREPARATION OF N‐MONOSUBSTITUTED 3‐ISOTHIAZOLE AND 3‐(1,2,5‐THIADIAZOLE)AMINES. PREPARATION OF A NEW CLASS OF 2‐SUBSTITUTED 1,2,5‐THIADIAZOL‐3(2H)‐ONES
Authors: ROKACH J. , HAMEL P. , GIRARD Y. , READER G. 
Published: April 2016

AbstractAus dem Isothiazolon (Ia) bzw. dem Isothiadiazolinon (Ib) erhält man bei der Methylierung die Salze (II), die bei der Behandlung mit Ammoniak zu den Aminen (III) umlagern.
ChemInform Abstract: PRODUCTS OF 1,8‐CINEOLE OXIDATION BY A PSEUDOMONAD
Authors: MACRAE I. C. , ALBERTS V. , CARMAN R. M. , SHAW I. M. 
Published: April 2016

AbstractAus Eukalyptusblättern wurde eine Bakterie isoliert, die in naher Verwandtschaft zu Pseudomonas flava steht.
ChemInform Abstract: DRUG‐INDUCED MODIFICATIONS OF THE IMMUNE RESPONSE. 1. SUBSTITUTED 1‐PHENYLISOQUINOLINES
Authors: ST. GEORGIEV V. , CARLSON R. P. , VAN INWEGEN R. G. , KHANDWALA A. 
Published: April 2016

AbstractAus dem Phenethylamin (I) erhält man über das Amid (III) das Dihydroisochinolin (IV), das zum Tetrahydroisochinolin (V) reduziert wird.
ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF 2,3,4,5‐TETRAHYDRO‐1,5‐METHANO‐1H‐3‐BENZAZEPINES
Authors: MAZZOCCHI P. H. , STAHLY B. C. 
Published: April 2016

AbstractDie Synthese des Benzazepins (VII) gelingt ausgehend von dem Alkohol (I) über die bislang unbekannte Dicarbonsäure (IV).
ChemInform Abstract: SYNTHESIS OF P‐ AND M‐(ADAMANTYL)ARYLCHLOROSILANES
Authors: MIRONOV V. F. , FEDOTOV N. S. , EVERT G. E. , KUZNETSOVA M. G. , KISIN A. V. 
Published: April 2016

AbstractErhitzt man Chloradamantan (I), Phenyltrichlorsilan (II) und Aluminiumchlorid im Verhältnis 4213:1, dann entstehen die m‐, p‐Adamantyl‐phenyl‐trichlorsilane (III) neben 3,5‐Diadamantyl‐phenyl‐trichlorsilan (IV).
ChemInform Abstract: REACTION OF THREE‐COORDINATE PHOSPHORUS CHLORIDES WITH NONSYMMETRICAL FUNCTIONALLY SUBSTITUTED ACETALS
Authors: GAZIZOV M. V. 
Published: April 2016

AbstractPhosphortrichlorid (I) reagiert mit dem Acetal (II) im Molverhältnis 1:1 zur Verbindung (III), mit Molverhältnis 1:3 bildet sich die Verbindung (IV); in Anwesenheit von Acetanhydrid entstehen die Substanzen (III), (VI) und (VII) sowie Polymere.