bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reading‐Related Causal Attributions for Success and Failure: Dynamic Links With Reading Skill
Authors: Frijters Jan C. , Tsujimoto Kimberley C. , Boada Richard , Gottwald Stephanie , Hill Dina , Jacobson Lisa A. , Lovett Maureen W. , Mahone E. Mark , Willcutt Erik G. , Wolf Maryanne , Bosson‐Heenan Joan , Gruen Jeffrey R. 
Published: April 2017

AbstractThe present study investigated the relation among reading skills and attributions, naming speed, and phonological awareness across a wide range of reading skill. Participants were 1,105 school‐age children and youths from two understudied populations: African Americans and Hispanic Americans. Individual assessments of children ranging in age from 8 to 15 years were conducted for reading outcomes, cognitive and linguistic predictors of reading, and attributions for success and failure in reading situations. Quantile regressions were formulated to estimate these relations across the full skill span of each outcome. Reading‐related attributions predicted contextual word recognition, sight word and decoding fluency, and comprehension skills. Attributions to ability in success situations were positively related to each outcome across the full span. On three reading outcomes, this relation strengthened at higher skill levels. Attributions to effort in success situations were consistently and negatively related to all reading outcomes. The results provide evidence that the strength of the relation between reading and attributions varies according to reading skill levels, with the strongest evidence for ability‐based attributions in situations of reading success.
Systems biology of cellular membranes: a convergence with biophysics
Authors: Chabanon Morgan , Stachowiak Jeanne C. , Rangamani Padmini 
Published: May 2017

Systems biology and systems medicine have played an important role in the last two decades in shaping our understanding of biological processes. While systems biology is synonymous with network maps and ‘‐omics’ approaches, it is not often associated with mechanical processes. Here, we make the case for considering the mechanical and geometrical aspects of biological membranes as a key step in pushing the frontiers of systems biology of cellular membranes forward. We begin by introducing the basic components of cellular membranes, and highlight their dynamical aspects. We then survey the functions of the plasma membrane and the endomembrane system in signaling, and discuss the role and origin of membrane curvature in these diverse cellular processes. We further give an overview of the experimental and modeling approaches to study membrane phenomena. We close with a perspective on the converging futures of systems biology and membrane biophysics, invoking the need to include physical variables such as location and geometry in the study of cellular membranes. WIREs Syst Biol Med 2017, 9:e1386. doi: 10.1002/wsbm.1386This article is categorized under:

Models of Systems Properties and Processes > Cellular Models
Biological Mechanisms > Cell Signaling
Models of Systems Properties and Processes > Mechanistic Models
A Different Kind of Craving: Incidence and Treatment of Pica After Laparoscopic Roux‐en‐Y Gastric Bypass
Authors: Van Osdol Andrew D. , Kallies Kara J. , Fredrickson Kyla A. , Kothari Shanu N. 
Published: May 2017

AbstractBackgroundIron deficiency can occur in patients after Roux‐en‐y gastric bypass due to altered absorption. Pica, the compulsive craving and intake of non‐nutritive substances, is a rare and poorly understood presentation of iron deficiency. To our knowledge, the rate of pica after RYGB has never been reported.MethodsThe medical records of patients who underwent laparoscopic RYGB from 2001 to 2011 were reviewed. Patients with pica or other abnormal cravings were identified.ResultsPica was identified in 16/959 (1.7%) patients who underwent RYGB during the study period. The most common presenting sign was pagophagia. All patients with pica were female and had multiple risk factors for iron deficiency with 13/16 being premenopausal and 7/16 non‐compliant with oral iron supplementation. Pica symptoms presented at a mean of 3.9 ± 1.9 years after RYGB. Iron deficiency was identified in all 16 patients, with a median ferritin level of 5.0 ng/mL (range 2–27). All 16 patients received intravenous iron and pica symptoms resolved.ConclusionsPica is a rare phenomenon associated with iron deficiency and can occur despite oral iron supplementation. In our experience, intravenous iron can relieve symptoms. Patients considering bariatric surgery should be counseled on pica. Patients with unusual cravings should be evaluated for iron deficiency.
Description and genetic characterization of a newContracaecumlarval type (Nematoda: Anisakidae) from Australia
Authors: Shamsi S. , Turner A. , Wassens S. 
Published: May 2017

AbstractNematode parasites belonging to the genusContracaecumare economically important parasites with zoonotic significance. AdultContracaecumspp. are found in the stomach of marine mammals or piscivorous birds, and larval stages infect a wide range of invertebrates and fish species. Human infection withContracaecumlarvae has been reported in Australia and other countries after the consumption of infected fish. Although the genusContracaecumcomprises numerous species, thus far only fourContracaecumlarval types have been specifically identified, therefore their life cycle and biology are not yet fully understood. In this study, a newContracaecumlarva (type IV), found in the intestinal tissue of carp caught from Coonancoocabil Lagoon, New South Wales, Australia, is described and characterized genetically. It was identified asContracaecum bancrofti,a unique Australian species reported previously from the Australian pelican in Northern Territory, New South Wales, Victoria and South Australia. This study highlights the role of migratory birds and introduced fish species, such as carp, in distributing zoonotic pathogens not only across the continent but also from marine to freshwater systems. Coonancoocabil Lagoon is located in the Murrumbidgee Valley National Park, a highly managed conservation area with native fish in wetlands located in close proximity to several fish farms and hatcheries. Infection of a highly resilient invasive fish species, such as carp, with a zoonotic parasite of low host specificity, such asContracaecumlarvae, should be alarming for aquaculture and environmental authorities.
Nickel-catalysed retro-hydroamidocarbonylation of aliphatic amides to olefins
Authors: Hu Jiefeng , Wang Minyan , Pu Xinghui , Shi Zhuangzhi 
Published: May 2017

AbstractAmide and olefins are important synthetic intermediates with complementary reactivity which play a key role in the construction of natural products, pharmaceuticals and manmade materials. Converting the normally highly stable aliphatic amides into olefins directly is a challenging task. Here we show that a Ni/NHC-catalytic system has been established for decarbonylative elimination of aliphatic amides to generate various olefins via C–N and C–C bond cleavage. This study not only overcomes the acyl C–N bond activation in aliphatic amides, but also encompasses distinct chemical advances on a new type of elimination reaction called retro-hydroamidocarbonylation. This transformation shows good functional group compatibility and can serve as a powerful synthetic tool for late-stage olefination of amide groups in complex compounds.
ZnO@C (core@shell) microspheres derived from spent coffee grounds as applicable non-precious electrode material for DMFCs
Authors: Ghouri Zafar Khan , Al-Meer Saeed , Barakat Nasser A. M. , Kim Hak Yong 
Published: May 2017

AbstractAlthough numerous reports have introduced non precious electrocatalysts for methanol oxidation, most of those studies did not consider the corresponding high onset potential which restricts utilization in real fuel cells. In this study, an −90 mV [vs. Ag/AgCl] onset potential non-precious electrocatalyst is introduced as an applicable anode material for the direct methanol fuel cells. Moreover, the proposed material was prepared from a cheap and abundantly existing resource; the spent coffee grounds. Typically, the spent coffee grounds were facilely converted to core@shell (ZnO@C) microspheres through a two-step approach, involving chemical activation and a subsequent calcination at temperature of 700 °C. Activation of the carbon derived from the spent coffee grounds was performed with ZnCl2 which acts as pore-forming agent as well as a precursor for the ZnO. The structure and morphology were characterized by (XRD), (SEM), and (TEM) analyses while the electrochemical characterizations was evaluated by cyclic voltammetry (CV) technique. Besides the comparatively very low onset potential, the introduced microspheres exhibited relatively high current density; 17 mA/cm2. Overall, based on the advantages of the green source of carbon and the good electrocatalytic activity, the spent coffee grounds-derived carbon can be considered a promise anode material for the DMFCs.
A Photochemical Avenue to Photoluminescent N-Dots and their Upconversion Cell Imaging
Authors: Jin Qingqing , Gubu Amu , Chen Xiuxian , Tang Xinjing 
Published: May 2017

AbstractA photochemical avenue to synthesize nitrogen-rich quantum dots (N-dots) using 2-azido imidazole as the starting material was established for the first time. A production yield of up to 92.7% was obtained. The N-dots were then fully characterized by elemental analysis, IR, XPS, XRD, AFM and TEM. On the basis of the N2 production and in situ IR results, the underlying mechanism for the photochemical formation of N-dots was proposed. These N-dots showed promising optical properties including wavelength-dependent upconversion photoluminescence, and were successfully used in upconversion cell imaging.
Symmetry breaking during homodimeric assembly activates an E3 ubiquitin ligase
Authors: Ye Zhaofeng , Needham Patrick G. , Estabrooks Samuel K. , Whitaker Susan K. , Garcia Brandon L. , Misra Saurav , Brodsky Jeffrey L. , Camacho Carlos J. 
Published: May 2017

AbstractC-terminus of Hsc/p70-Interacting Protein (CHIP) is a homodimeric E3 ubiquitin ligase. Each CHIP monomer consists of a tetratricopeptide-repeat (TPR), helix-turn-helix (HH), and U-box domain. In contrast to nearly all homodimeric proteins, CHIP is asymmetric. To uncover the origins of asymmetry, we performed molecular dynamics simulations of dimer assembly. We determined that a CHIP monomer is most stable when the HH domain has an extended helix that supports intra-monomer TPR-U-box interaction, blocking the E2-binding surface of the U-box. We also discovered that monomers first dimerize symmetrically through their HH domains, which then triggers U-box dimerization. This brings the extended helices into close proximity, including a repulsive stretch of positively charged residues. Unable to smoothly unwind, this conflict bends the helices until the helix of one protomer breaks to relieve the repulsion. The abrupt snapping of the helix forces the C-terminal residues of the other protomer to disrupt that protomer’s TPR-U-box tight binding interface, swiftly exposing and activating one of the E2 binding sites. Mutagenesis and biochemical experiments confirm that C-terminal residues are necessary both to maintain CHIP stability and function. This novel mechanism indicates how a ubiquitin ligase maintains an inactive monomeric form that rapidly activates only after asymmetric assembly.
Systematic evaluation for effects of urine pH on calcium oxalate crystallization, crystal-cell adhesion and internalization into renal tubular cells
Authors: Manissorn Juthatip , Fong-ngern Kedsarin , Peerapen Paleerath , Thongboonkerd Visith 
Published: May 2017

AbstractUrine pH has been thought to be an important factor that can modulate kidney stone formation. Nevertheless, there was no systematic evaluation of such pH effect. Our present study thus addressed effects of differential urine pH (4.0–8.0) on calcium oxalate (CaOx) crystallization, crystal-cell adhesion, crystal internalization into renal tubular cells, and binding of apical membrane proteins to the crystals. Microscopic examination revealed that CaOx monohydrate (COM), the pathogenic form, was crystallized with greatest size, number and total mass at pH 4.0 and least crystallized at pH 8.0, whereas COD was crystallized with the vice versa order. Fourier-transform infrared (FT-IR) spectroscopy confirmed such morphological study. Crystal-cell adhesion assay showed the greatest degree of crystal-cell adhesion at the most acidic pH and least at the most basic pH. Crystal internalization assay using fluorescein isothiocyanate (FITC)-labelled crystals and flow cytometry demonstrated that crystal internalization into renal tubular cells was maximal at the neutral pH (7.0). Finally, there were no significant differences in binding capacity of the crystals to apical membrane proteins at different pH. We concluded that the acidic urine pH may promote CaOx kidney stone formation, whereas the basic urine pH (i.e. by alkalinization) may help to prevent CaOx kidney stone disease.
Effect of Message Type on the Visual Attention of Adults With Traumatic Brain Injury
Authors: Thiessen Amber , Brown Jessica , Beukelman David , Hux Karen , Myers Angela 
Published: May 2017

Purpose
The purpose of this investigation was to measure the effect of message type (i.e., action, naming) on the visual attention patterns of individuals with and without traumatic brain injury (TBI) when viewing grids composed of 3 types of images (i.e., icons, decontextualized photographs, and contextualized photographs).

Method
Fourteen adults with TBI and 14 without TBI—assigned either to an action or naming message condition—viewed grids composed of 3 different image types. Participants' task was to select/sustain visual fixation on the image they felt best represented a stated message (i.e., action or naming).

Results
With final fixation location serving as a proxy for selection, participants in the naming message condition selected decontextualized photographs significantly more often than the other 2 image types. Participants in the action message condition selected contextualized photographs significantly more frequently than the other 2 image types. Minimal differences were noted between participant groups.

Conclusions
This investigation provides preliminary evidence of the relationship between image and message type. Clinicians involved in the selection of images used for message representation should consider the message being represented when designing supports for people with TBI. Further research is necessary to fully understand the relationship between images and message type.
Management of early gastric cancer with positive horizontal or indeterminable margins after endoscopic submucosal dissection: multicenter survey
Authors: Ishii Naoki , Omata Fumio , Fujisaki Junko , Hirasawa Toshiaki , Kaise Mitsuru , Hoteya Shu , Tanabe Satoshi , Ishido Kenji , Ohata Ken , Takita Maiko , Mine Tetsuya , Igarashi Muneki , Yoshida Tatsuya , Takeda Yuichi , Furumoto Yohei , Matsumoto Kenshi , Yahagi Naohisa , Nakashima Hirotaka , Wada Tomonori , Tagata Tomoko , Mitsunaga Atsushi 
Published: May 2017

Abstract
Background and study aims Positive horizontal margins in resected specimens are sometimes encountered after endoscopic submucosal dissection (ESD) for early gastric cancers, and appropriate treatment strategies for these cases are not established. The aim of this study was to evaluate current empirical treatments for patients with positive horizontal or indeterminable margins after ESD.
Patients and methods We performed a multicenter survey and data from 14 hospitals were collected. The pooled proportions of positive horizontal or indeterminable margins and those of patients followed up without early intervention were calculated using a logistic-normal random-effects model. For calculating pooled estimates, subgroup analyses of high- and non-high-volume centers were conducted.
Results A total of 11,796 ESD cases were enrolled and 229 patients (2 %) had positive horizontal or indeterminable margins. Ninety-eight cases were treated within 30 days of ESD and 131 cases were followed up without early treatments. Pooled estimates of positive margins in high- and non-high-volume centers were 1 % (95 % CI: 1 % – 2 %) and 2 % (95 % CI: 1 % – 4 %), respectively, and were not heterogeneous (P = 0.191). The proportion of patients followed up without early intervention ranged from 30 % to 100 %. The pooled estimate was 68 % (95 % CI: 50 % – 83 %). The pooled estimates of high- and non-high-volume centers were 65 % (95 % CI: 38 % – 85 %) and 72 % (95 % CI: 44 % – 89 %), respectively, and were not heterogeneous (P = 0.692).
Conclusion There was insufficient consensus regarding treatment strategies used for early gastric cancer with positive horizontal or indeterminable margins after ESD. Further studies are required to establish a consensus.
Use of over-the-scope clips (OTSC) for hemostasis in gastrointestinal bleeding in patients under antithrombotic therapy
Authors: Lamberts Regina , Koch Anna , Binner Christian , Zachäus Marcus , Knigge Ingrid , Bernhardt Mark , Halm Ulrich 
Published: May 2017

Abstract
Background and study aims In patients taking different regimens of antithrombotic and/or anticoagulant therapy, endoscopic management of gastrointestinal bleeding represents a major challenge due to failing endogenous hemostasis. In this retrospective study we report on success rates with the over-the-scope clip (OTSC) system in upper and lower gastrointestinal bleeding in this high-risk patient population.
Patients and methods Between February 2011 and June 2014, 75 patients were treated with an OTSC for active gastrointestinal bleeding. Success rates with the first endoscopic therapy, rebleeding episodes, their management and the influence of antithrombotic or anticoagulant therapy were analyzed retrospectively.
Results Application of the OTSC resulted in immediate hemostasis (primary success rate) in all 75 patients. However, in 34.7 % a rebleeding episode was noted that could be treated by further endoscopic interventions. Only 3 patients had to be sent to the operating room because of failure of endoscopic therapy. In the rebleeding group the use of antiplatelet therapies was higher (73.1 % vs. 48.9 %).
Conclusions Application of the OTSC in GI bleeding results in a high rate of primary hemostasis. Rebleeding occurs in up to 35 % of patients receiving antithrombotic/anticoagulant therapy but can be managed successfully with further endoscopic treatments. Patients in the rebleeding group were more frequently treated with antiplatelet agents. Radiological or surgical therapy was reserved for a small subgroup not successfully managed by repeated endoscopic therapies. OTSC application is the treatment of choice in high-risk patients when conventional clips used as first-line treatment fail.
Is Knowledge Power? Information and Switching Costs in Agricultural Markets
Authors: Mitchell Tara 
Published: April 2017

AbstractThis article investigates an important channel through which access to information about market prices could increase the prices that producers receive from middlemen. I develop a model of trade between a farmer and a middleman, allowing for middlemen to differ in terms of their social preferences, and provide an empirical test of the theory using a framed field experiment carried out in India. The model predicts a non‐monotonic relationship between the benefit of information and the cost of switching to a new middleman. I find that actual middlemen do differ with regard to their social preferences, and that the benefit of information to the farmer varies with the cost of switching. While it is not possible to confirm a non‐monotonic relationship between the benefit of information and the cost of switching based on these data, the results are consistent with the predictions of the model.
Missing dust signature in the cosmic microwave background
Authors: Vavryčuk Václav 
Published: May 2017

Abstract
I examine a possible spectral distortion of the cosmic microwave background (CMB) due to its absorption by galactic and intergalactic dust. I show that even subtle intergalactic opacity of 1 × 10−7 mag h Gpc−1 at the CMB wavelengths in the local Universe causes non-negligible CMB absorption and decline of the CMB intensity because the opacity steeply increases with redshift. The CMB should be distorted even during the epoch of the Universe defined by redshifts z &lt; 10. For this epoch, the maximum spectral distortion of the CMB is at least 20 × 10−22 W m−2 Hz−1 sr−1 at 300 GHz, which is well above the sensitivity of the COBE/FIRAS, WMAP or Planck flux measurements. If dust mass is considered to be redshift dependent with noticeable dust abundance at redshifts 2–4, the predicted CMB distortion would be even higher. The CMB would also be distorted in a perfectly transparent universe due to dust in galaxies, but this effect is lower by one order than that due to intergalactic opacity. The fact that the distortion of the CMB by dust is not observed is intriguing and questions either opacity and extinction law measurements or validity of the current model of the Universe.
Mindfulness-based Cognitive Therapy and Persistent Pain in Women Treated for Primary Breast Cancer
Authors: Johannsen Maja , O’Connor Maja , O’Toole Mia S. , Jensen Anders B. , Zachariae Robert 
Published: May 2017

Objectives:
The aim of this study was to investigate possible statistical mediators in a randomized controlled trial of mindfulness-based cognitive therapy (MBCT) on pain intensity in women treated for primary breast cancer.

Materials and Methods:
The sample consisted of 129 women treated for breast cancer, presenting with persistent pain, who were randomly assigned to MBCT or a wait-list control. We previously reported a statistically significant and robust effect of MBCT on pain intensity (11-point numeric rating scale), which was included as the primary outcome. The proposed mediators were mindfulness (the Five Facet Mindfulness Questionnaire), self-compassion (the Short-Form Self-Compassion Scale), and pain catastrophizing (the Pain Catastrophizing Scale). Measurement points included baseline (T1), postintervention (T2), and 3- (T3) and 6-month (T4) follow-ups. All indirect effects of the mediators were tested in separate Multilevel Models, using the product-of-coefficients approach with bias-corrected confidence intervals (95% BSCI). The statistically significant mediators were then included in a multiple mediator model.

Results:
Statistically significant indirect effects were found for mindfulness nonreactivity (B=−0.17, BSCI [−0.32 to −0.04]) and pain catastrophizing (B=−0.76, BSCI [−1.25 to −0.47]). No statistically significant indirect effect was found for self-compassion (B=−0.09, BSCI [−0.30 to 0.04]). In a multiple mediator model, including mindfulness nonreactivity and pain catastrophizing, only pain catastrophizing remained statistically significant (B=−0.72, BSCI [−1.19 to −0.33]), explaining 78% of the effect.

Discussion:
The results of the present study may have clinical implications. An increased focus on the proposed mediators may optimize the clinical use of MBCT for persistent pain in women treated for breast cancer.