bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of age and body mass index on the yield of stromal vascular fraction
Authors: Alaaeddine Nada , El Atat Oula , Saliba Nagib , Feghali Ziad , Nasr Marwan , Tarabey Bilal , Hilal George , Hashim Hussein 
Published: December 2017

SummaryObjectiveThe aim of this study was to determine the influence of age, body mass index, and site of liposuction on the cell yield of SVF.MethodsA prospective study was performed on 58 patients. The average age was 39 years old, with BMI ≤ 25 or BMI ≥ 25. Fat tissue was harvested from the abdominal region, flanks, or thighs and SVF was isolated.ResultsThe yield of viable SVF was evaluated by trypan blue, and the markers of stem cells were evaluated by flow cytometry. The cells were positive for stem cells markers, the age, sex of the patient had no impact on SVF cell yield with an average of 1.17 × 10^8. However, the BMI > 25 had resulted in higher cell numbers, and the harvest site had a significant impact on cell yield with abdomen being the site of interest.ConclusionThese data demonstrate that the age of the person does not affect the cell yield of SVF; nevertheless, the donor site and BMI might be important factors in affecting cell number.
Influence of Implant Position in Implant‐Assisted Removable Partial Denture: A Three‐Dimensional Finite Element Analysis
Authors: Ortiz‐Puigpelat Octavi , Lázaro‐Abdulkarim Aida , de Medrano‐Reñé Javier‐María , Gargallo‐Albiol Jordi , Cabratosa‐Termes Josep , Hernández‐Alfaro Federico 
Published: December 2017

AbstractPurposeTo determine the ideal position of a dental implant to assist a posterior extended partial removable dental prosthesis (PRDP), through stress values, displacement values, and deformation of periodontal ligament (PDL).Materials and MethodsA finite element analysis of different implant positions was analyzed using a 3D mandible model from a human patient. Test models were created: model A (implant in second molar area), model B (implant in the first molar area), and model C (implant in premolar area). A control model without implant support was also created. Overall displacement values, von Mises stress distribution maps, and nonlinear deformations were evaluated.ResultsSome differences could be observed between test models. The introduction of an implant in the edentulous area, unlike a conventional removable partial denture without implant support, decreases stress values in the biological structures such as: mandible, tooth, soft tissue, and PDL. Placing the implant in the first molar area resulted in improved displacement values, and reduced maximum stress values at the peri‐implant bone area, metal structure, and implant were observed.ConclusionsWithin the limitations of this study we can conclude that placing the implant in the position of the first molar improves biomechanical behavior of implant‐assisted PRDPs.
Bringing the (disabled) body to personality psychology: A case study of Samantha
Authors: Adler Jonathan M. 
Published: December 2017

AbstractObjectivePersonality psychology has largely ignored the experiences of people with disabilities. This article strives to bring the thriving, interdisciplinary field of disability studies to personality psychology via a case study of Samantha (N = 1). Samantha feels that she grew up as a hearing person who could not hear and is now a deaf person who can hear.MethodNarrative identity provides the theoretical, methodological, and analytical framework for the rich, qualitative examination of Samantha's life story, interwoven with approaches from disability studies and intersectionality theory. Two Life Story Interviews (McAdams, 2008), conducted 2 weeks prior to Samantha's cochlear implant surgery and again 7 weeks after the surgery, provide the foundation for this case study and are interpreted alongside additional self‐report measures. Grounded theory methods were used to interpret Samantha's narrative identity.ResultsSamantha's story demonstrates the ways in which narrative identity can serve as a foundation for meaning and psychological well‐being, as well as a demonstration of the ways in which the study of identity can be enriched by perspectives from disability studies.ConclusionsAs an initial effort at integrating personality psychology and disability studies, this article sought to approach this task by privileging ethical representation over generalizability.
Depressive personality vulnerability in chronic physical pain: Centrality of sociotropy
Authors: Shahar Golan , Lerman Sheera F. , Topaz Maayan , Brill Silviu , Shalev Hadar , Rudich Zvia 
Published: December 2017

AbstractObjectiveChronic physical pain is one of modern medicine's principal challenges. Recently, there has been a keen research interest in the role of depressive personality vulnerability (DPV) in the course of chronic pain. This is the first attempt to examine the role of three leading DPV dimensions—sociotropy, autonomy, and self‐criticism—in chronic pain.MethodChronic pain patients (N = 428) were assessed four times as to their pain, disability, anxious depression, and pain‐based catastrophizing. At Time 1, sociotropy, autonomy, and self‐criticism were also assessed. The effects of sociotropy, autonomy, and self‐criticism on pain, disability, anxious depression, and pain‐based catastrophizing were examined using structural equation modeling analyses.ResultsAll DPV dimensions uniquely predicted Time 1, but not Time 2, anxious depression. Sociotropy predicted Time 1 pain and catastrophizing over and above anxious depression, as well as an increase in catastrophizing over time. Autonomy predicted a decrease in catastrophizing and disability, and Time 1 anxious depression predicted an increase in self‐criticism.ConclusionsSociotropy appears to be a unique dimension of DPV in chronic pain.
Benefits of emotional integration and costs of emotional distancing
Authors: Roth Guy , Shahar Bat‐Hen , Zohar‐Shefer Yael , Benita Moti , Moed Anat , Bibi Uri , Kanat‐Maymon Yaniv , Ryan Richard M. 
Published: December 2017

AbstractObjectiveThree studies explored the consequences of the self‐determination theory conception of integrative emotion regulation (IER; Ryan & Deci, 2017), which involves an interested stance toward emotions. Emotional, physiological, and cognitive consequences of IER were compared to the consequences of emotional distancing (ED), in relation to a fear‐eliciting film.MethodIn Study 1, we manipulated emotion regulation by prompting students' (N = 90) IER and ED and also included a control group. Then we tested groups' defensive versus nondefensive emotional processing, coded from post‐film written texts. Study 2 (N = 90) and Study 3 (N = 135) used the same emotion regulation manipulations but exposed participants to the fear‐eliciting film twice, 72 hr apart, to examine each style's protection from adverse emotional, physiological, and cognitive costs at second exposure.ResultsParticipants who had been prompted to practice IER were expected to benefit more than participants in the ED and control groups at second exposure, as manifested in lower arousal and better cognitive capacity. Overall, results supported our hypotheses.ConclusionsThe current studies provide some support for the assumption that in comparison to ED, taking interest in and accepting one's negative emotions are linked with less defensive processing of negative experiences and with better functioning.
REGIONAL 3D MODELLING OF THE PERMO‐CARBONIFEROUS AL KHLATA FORMATION IN THE RIMA AREA, EASTERN FLANK OF THE SOUTH OMAN SALT BASIN
Authors: Al‐Abri F. G. , Heward A. P. , Abbasi I. A. 
Published: December 2017

The glaciogenic Al Khlata Formation (Late Carboniferous – Early Permian) contains important reservoir and seal intervals in oil fields in southern Oman. Here we describe a 3D regional geological model of the Al Khlata Formation and the underlying Misfar Group in a 1750 km2 area in the Eastern Flank of the South Oman Salt Basin. The Misfar Group (Devonian‐Carboniferous?) was included in the model because it also contains glaciogenic facies in the study area. The 3D model is based on wireline logs from 42 wells, palynological zonation in 31 wells, cores from three wells, and a 2011 3D seismic dataset from which three horizons (top‐Huqf, top‐Rahab Shale and top‐Gharif) were interpreted throughout the study area.The combined Al Khlata and Misfar interval varies in thickness in the area from 20 to 730 m over relatively short distances. These large variations in thickness were due to the creation of accommodation in mini‐basins resulting from the removal of underlying Infracambrian salt at the basin margin. In places, some of the available accommodation was occupied by Cambrian sandstones of the Nimr Group and Haima Supergroup, influencing the location and thickness of the Al Khlata mini‐basins. These local depocentres vary in scale, shape and orientation relative to the present‐day salt edge: some are ovoid in plan‐view, others more linear and parallel to the salt edge, and one takes the form of a narrow graben almost perpendicular to the salt edge. By the Early Permian, towards the end of Al Khlata time, deposits become more blanket‐like and uniform, indicating an external or more regional control on base level.Four key lithofacies have been distinguished from wireline logs and were populated zone‐by‐zone through the geological model: sandstone (reservoir), shale (seal), and sandy and silty diamictite. Sandstones are most common towards the base of the Misfar – Al Khlata interval and shales towards the top. The Rahab Shale (Early Permian) at the top of the Al Khlata Formation forms an important seal for oil fields in South Oman, often in combination with seals in overlying intervals. The Rahab Shale was the first widespread seal to be deposited which may have trapped oil migrating from the South Oman Salt Basin during the Palaeozoic.The most common lithofacies in the Misfar – Al Khlata interval in the modelled area is diamictite (60%), which is normally considered to be a waste‐rock lithology. However thick silty diamictites of sufficient extent can seal hydrocarbon accumulations, and some sandy diamictites have the potential to be unconventional reservoir rocks.Even after 50 years of exploration and production of oil from the Al Khlata Formation, there remains potential for further discoveries and overlooked pay zones due to its heterogeneous character and the occurrence of intra‐formational seals.
BURIAL AND THERMAL HISTORY MODELLING OF THE EDIACARAN SUCCESSION IN WESTERN AND SW UKRAINE AND MOLDOVA
Authors: Radkovets N. , Kosakowski P. , Rauball J. , Zakrzewski A. 
Published: December 2017

The Ediacaran (Upper Neoproterozoic) succession in west and SW Ukraine and Moldova rests on a Cryogenian succession or basement. The succession is exposed at the surface along the southern margin of the Ukrainian Shield and dips to the SW towards the Carpathian Overthrust; where burial depths are sufficient, it is mature for oil and gas generation. The Ediacaran succession is made up of terrigenous siliciclastics ranging from conglomerates and sandstones to siltstones and mudstones, and includes a shale interval (the Kalus Beds) which may have source rock potential. Organic matter in the Kalus shales includes Vendotenides sp. (colonial bacteria) together with amorphous OM. This paper presents a study of the Kalus Beds and is based on data from surface and core samples and thin sections, and the results of Rock‐Eval pyrolysis and reflectance analyses. TOC contents in the Kalus shales are in general <0.5 wt%, although the measured TOC was 0.89 wt% and 0.84 wt%, respectively, in samples from the Sokal‐1 borehole and the Mynkivtsi outcrop location in SW Ukraine. The low present‐day TOC in borehole samples may be due to the thermal transformation of the OM originally present. Reflectivity as measured on vitrinite‐like macerals and bitumen in samples from outcrops ranges from 0.63 to 1.28% VRoeq indicating a relatively low level of thermal maturity. However, the generally low TOC values in the outcrop samples mean that the Kalus Beds in general have little hydrocarbon potential in the study area.The burial and thermal history of the Ediacaran succession in SW Ukraine and the Moldovian Platform was reconstructed, and 1D modelling was carried out at the Brody‐1, Chernivtsi‐1, Dobrotvir‐1, Kolynkiv‐1, Litovyzh‐1, Ludyn‐1, Lyman‐1, Peremyshlyany‐1, Sokal‐1 and Voyutyn‐1 boreholes. The results of modelling indicate that maturities equivalent to the onset of the oil window were reached from the Early Devonian through the Early Carboniferous. Slightly higher modelled maturities occurred in boreholes located near the Teisseyre‐Tornquist Zone. The modelled transformation ratio for kerogen in the Kalus Beds is high and may exceed 90% in the boreholes studied.
Liver zonation in children with non‐alcoholic fatty liver disease: Associations with dietary fructose and uric acid concentrations
Authors: Nobili Valerio , Mosca Antonella , De Vito Rita , Raponi Massimiliano , Scorletti Eleonora , Byrne Christopher D. 
Published: December 2017

AbstractBackground & AimsAs dietary components are delivered directly to the periportal zone of the liver lobule, there is the potential for greater injury in this zone (zone 1) compared to the perivenous zone (zone 3). We investigated the associations between dietary fructose consumption and uric acid concentrations and differential zonal injury in periportal and perivenous zones.MethodsA total of 271 children's histological images were scored in 5 periportal and 5 perivenous zones for steatosis, ballooning, inflammation and fibrosis severity. Dietary fructose consumption (g/d) was assessed and uric acid measured in serum. Logistic regression was undertaken to test associations between both high fructose consumption and hyperuricaemia, and histological disease in periportal and perivenous zones.ResultsChildren with a mean age of 12.5 years were included in the study. Inflammation (mean ± SD) was increased in the periportal vs perivenous zones (0.78 ± 0.43 vs 0.41 ± 0.48,P = .041). There were non‐significant trends towards greater steatosis, ballooning and fibrosis in the periportal zone. In the fully adjusted models, high fructose intake was associated with disease in both zones. Example for periportal and perivenous zones, respectively, steatosis 1.56 (1.12, 2.49) and 1.21 (1.09, 2.73); inflammation 4.29 (2.31, 5.88) and 3.69 (2.14, 4.56); and fibrosis 2.72 (1.43, 3.76) and 1.96 (1.24, 2.37). Hyperuricaemia (uric acid ≥5.9 mg/dL) was associated with inflammation in the periportal zone 1.71 (1.17, 2.35); and was associated with steatosis and fibrosis in both zones; for example, for periportal and perivenous zones, respectively, steatosis 2.98 (1.65, 3.23) and 1.14 (1.05, 1.99); and fibrosis, 2.65 (1.35, 2.99) and 1.31 (1.13, 2.17).ConclusionsHigh fructose consumption is associated with disease severity in both lobular zones and hyperuricaemia may be associated with more severe disease in the periportal zone.
Drug‐induced acute liver failure in children and adults: Results of a single‐centre study of 128 patients
Authors: Devarbhavi Harshad , Patil Mallikarjun , Reddy Vishnu V. , Singh Rajvir , Joseph Tarun , Ganga Deepak 
Published: December 2017

AbstractBackground & AimsDrugs producing acute liver failure (ALF) are uncommon and vary geographically. Here we review the implicated drugs, clinical features, laboratory characteristics and outcome of patients with drug‐induced ALF (DIALF). We analysed the predictors of mortality and their relationship with MELD, King's College criteria (KCC) and ALFSG prognostic index.MethodsWe identified DIALF patients from our drug‐induced liver injury (DILI) registry (1997‐2017). RUCAM was used for case adjudication. Patients who fulfilled criteria for acute liver failure and drug‐induced liver injury were included. Primary outcome measure was spontaneous survival or death.ResultsThere were 128 cases of DIALF (14%) among 905 patients with DILI. Mean age was 38 years, 68 (53%) female and 21(16.4%) children <18 years. Combination anti‐TB drugs (ATD) (n = 92, 72.4%) accounted for a majority of DIALF. Others were anti‐epileptic drugs (AED, n = 11, 10%), dapsone (n = 7, 5.5%), hormones (n = 2), ferrous sulphate overdose (n = 2), acetaminophen (APAP) (n = 2), antiretroviral (n = 2), CAM (N = 2), chemotherapy agents (N = 3), amoxicillin‐clavulanic acid (n = 2) and others (n = 3). Forty‐four patients (34%) recovered spontaneously and 84(66%) including 13 children (62%) died. Females, ascites, albumin, bilirubin, INR and MELD were significantly associated with mortality. Mortality was 79% for ATD and 100% for APAP and iron overdose. Area under ROC was 0.76 for MELD and ALFSG index and 0.51 for KCC.ConclusionsFourteen percent of DILI resulted in DIALF. ATD, AED, dapsone and antiretroviral drugs are most common agents. Spontaneous survival was only 34% with an even higher mortality with ATD. Non‐ATD and non‐APAP drugs had a better survival (51%).INR and MELD predicted mortality.
Non‐obese fatty liver disease is associated with lacunar infarct
Authors: Kwak Min‐Sun , Kim Kyung Won , Seo Hyobin , Chung Goh‐Eun , Yim Jeong Yoon , Kim Donghee 
Published: December 2017

AbstractBackground/AimsLacunar infarct, a small subcortical ischaemic lesion, is a known risk factor for future cognitive impairment, dementia and stroke. We evaluated the relationship between fatty liver disease (FLD) and lacunar infarct in a healthy general population.MethodsSubjects who underwent brain magnetic resonance imaging (MRI) and abdominal ultrasonography (US) during health check‐ups from 2007 to 2009 were included. FLD was diagnosed by US. Subjects with a history of cerebrovascular disease, radiological findings consistent with cerebrovascular stenosis or cerebral small vessel disease were excluded.ResultsOf the 1277 subjects, 54 (4.2%) exhibited lacunar infarct, and 514 (40.3%) had FLD. Subjects with lacunar infarct had a higher prevalence of FLD (59.3% vs 39.4%, P = .004). There was significant interaction between obesity (BMI < 25 kg/m2 vs ≥ 25 kg/m2) and FLD for lacunar infarct (P for interaction = .024). Subgroup analysis revealed that non‐obese FLD was more common in the subjects with lacunar infarct than those without (51.7% vs 23.5%, P = .001). However, there was no significant difference in the obese FLD prevalence between these 2 groups. In multivariate models adjusted by age, sex, smoking, alcohol, hypertension and diabetes, FLD was significantly associated with lacunar infarct (odds ratio [OR] 1.97; 95% confidence interval [CI] 1.08‐3.58; P = .027). Non‐obese FLD was associated with lacunar infarct (OR 3.58; 95% CI 1.63‐7.89; P = .002); however, this association remained insignificant in obese FLD. Instead, ageing and hypertension were independent risk factors for lacunar infarct in the obese population.ConclusionsFLD is significantly associated with lacunar infarct, independent of traditional risk factors. This association was prominent in the non‐obese population.
Localized versus regional adaptation in limpet shell morphology across the Iberian Peninsula
Authors: Hines Hunter N. , Morriss Hannah , Saunders Karen , Williams Rachel L. , Young Sarah L. , Stafford Richard 
Published: December 2017

AbstractThe climate‐envelope approach to predicting climate‐induced species range shift is limited. There are many possible reasons for this, but one novel explanation is that species adapt to changes in temperature at the expense of adaptation to other stressors. Here we test this hypothesis using the limpet Patella depressa (Mollusca, Patellidae), over a large geographical area covering most of the Atlantic coast of the Iberian Peninsula, known to consist of a genetically inter‐connected population. We examine limpet shell morphology on four shores in each of three regions, from Northern Spain to Southern Portugal. Within each region, shell morphology (measured as maximum shell profile to length ratio) varied between shore types differing in their insolation, wave action, microhabitat availability and biological factors. However, this ratio, which is known to be an adaptive response to heat stress, was found to be consistently higher in more southern latitudes despite differences between shore types being found in all regions. This implies that localized adaptation to shore type (most likely through phenotypic plasticity) is compromised by factors that change over latitudinal or regional scales, or which could occur in response to climate change. Although such climate‐induced changes may initially be localized, compromised adaptation (through phenotypic or genetic plasticity) may result in altered community interactions and potentially large shifts in community structure.
The incidence and outcomes of delayed response to cardiac resynchronization therapy
Authors: Li Kebei , Qian Zhiyong , Hou Xiaofeng , Wang Yao , Qiu Yuanhao , Sheng Yufeng , Qian Xuesong , Zhou Yong , Zou Jiangang 
Published: December 2017

AbstractBackgroundThe incidence and clinical outcomes of delayed response to cardiac resynchronization therapy (CRT) have not been well clarified. We aimed to observe the incidence and prognosis of delayed response and to identify its possible mechanisms.MethodsA total of 115 CRT patients were retrospectively analyzed in our study. Patients who met the enrollment criteria were divided into two groups: group A, conventional responders who showed response at 1‐year follow‐up, and group B, delayed responders who showed response after 1‐year follow‐up. CRT response was defined as an absolute increase of ≥10% in left ventricular ejection fraction.ResultsFifty‐two patients (61 ± 12 years, 37 male) experienced conventional response to CRT and 17 patients (63 ± 11 years, 10 male) experienced delayed response. The mean follow‐up time was 5.2 ± 2.4 years. The incidence of delayed response was 14.8% (17/115). All‐cause mortality and hospitalization rates for heart failure were similar for delayed and conventional responders. Multivariate logistic regression analysis revealed that scar burden > 35% was an independent predictor of CRT delayed response (odds ratio 8.794, P = 0.038).ConclusionsA significant proportion of patients demonstrated delayed response to CRT. The delayed responders had a good prognosis that was similar to that of conventional responders. More scar burden might be related to the incidence of delayed response.