bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maximal Aerobic Power in Aging Men: Insights From a Record of 1-Hour Unaccompanied Cycling
Authors: Capelli Carlo 
Published: April 2017

Purpose: To analyze best 1-h unaccompanied performances of master athletes in ages ranging from 35 to 105 y to estimate the decay of maximal aerobic power (MAP) across the spectrum of age. Methods: MAP at the various ages was estimated by computing the metabolic power () maintained to cover the distances during best 1-h unaccompanied performances established by master athletes of different classes of age and by assuming that they were able to maintain an equal to 88% of their MAP during 1 h of exhaustive exercise. Results: MAP started monotonically decreasing at 47 y of age. Thereafter, it showed an average rate of decrease of ∼14% for the decades up to 105 y of age, similar to other classes of master athletes. Conclusions: The results confirm, by extending the analysis to centennial subjects, that MAP seems to start declining from the middle of the 5th decade of age, with an average percentage decay that is faster than that traditionally reported, even when one maintains a very active lifestyle. The proposed approach may be applied to other types of human locomotion for which the relationship between speed and is known.
Psychometric Properties of the Brazilian Portuguese Version of the PARmed-X for Pregnancy
Authors: Bgeginski Roberta , DeSousa Diogo A. , Barroso Bruna M. , Vettorazzi Janete , Mottola Michelle F. , Schuch Felipe B. , Ramos José Geraldo L. 
Published: April 2017

Background:The Physical Activity Readiness Medical Examination (PARmed-X) for Pregnancy aims to facilitate the communication between the health care provider, the fitness professional and the pregnant woman. The purpose of the current study was to test the psychometric properties of the Brazilian Portuguese version of the PARmed-X for Pregnancy.Methods:Reliability and validity of psychometric properties of the Brazilian Portuguese version of the PARmed-X for Pregnancy were tested in 107 women recruited from the Hospital de Clínicas de Porto Alegre. Participants completed the first page of the instrument twice with a minimal interval of 1 week for test-retest reliability analysis. The absolute and relative contraindications to exercise on page 2 of the document were completed by the obstetrician.Results:Results indicated good evidence of construct validity. The isolated items in the PARmed-X document presented a large heterogeneity in kappa coefficients ranging from very low estimates to perfect estimates. The overall indication of prescription of physical activity, nonetheless, presented a good kappa coefficient of 0.749.Conclusions:The Brazilian Portuguese version of the PARmed-X for Pregnancy can be applied as a valid tool for medical screening by health care providers to help inform safe exercise prescription during pregnancy.
Energy Expenditure in Vinyasa Yoga Versus Walking
Authors: Sherman Sally A. , Rogers Renee J. , Davis Kelliann K. , Minster Ryan L. , Creasy Seth A. , Mullarkey Nicole C. , O’Dell Matthew , Donahue Patrick , Jakicic John M. 
Published: April 2017

Background:Whether the energy cost of vinyasa yoga meets the criteria for moderate-to-vigorous physical activity has not been established.Purpose:To compare energy expenditure during acute bouts of vinyasa yoga and 2 walking protocols.Methods:Participants (20 males, 18 females) performed 60-minute sessions of vinyasa yoga (YOGA), treadmill walking at a self-selected brisk pace (SELF), and treadmill walking at a pace that matched the heart rate of the YOGA session (HR-Match). Energy expenditure was assessed via indirect calorimetry.Results:Energy expenditure was significantly lower in YOGA compared with HR-Match (difference = 79.5 ± 44.3 kcal; P < .001) and SELF (difference = 51.7 ± 62.6 kcal; P < .001), but not in SELF compared with HR-Match (difference = 27.8 ± 72.6 kcal; P = .054). A similar pattern was observed for metabolic equivalents (HR-Match = 4.7 ± 0.8, SELF = 4.4 ± 0.7, YOGA = 3.6 ± 0.6; P < .001). Analyses using only the initial 45 minutes from each of the sessions, which excluded the restorative component of YOGA, showed energy expenditure was significantly lower in YOGA compared with HR-Match (difference = 68.0 ± 40.1 kcal; P < .001) but not compared with SELF (difference = 15.1 ± 48.7 kcal; P = .189).Conclusions:YOGA meets the criteria for moderate-intensity physical activity. Thus, YOGA may be a viable form of physical activity to achieve public health guidelines and to elicit health benefits.
Isotemporal Analysis of the Association of Objectively Measured Physical Activity With Depressive Symptoms: Results From Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
Authors: Rethorst Chad D. , Moncrieft Ashley E. , Gellman Marc D. , Arredondo Elva M. , Buelna Christina , Castañeda Shelia F. , Daviglus Martha L. , Khan Unab I. , Perreira Krista M. , Sotres-Alvarez Daniela , Stoutenberg Mark 
Published: April 2017

Background:The burden of depression among Hispanics/Latinos indicates the need to identify factors related to depressive symptoms. This paper examines the relationship of physical activity (PA) and sedentary behavior (SB) with depressive symptoms in Hispanic/Latinos.Methods:The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a population-based, cohort study of Hispanic/Latinos in 4 United States metropolitan areas. Objectively measured PA was coded into: sedentary behavior (SB), light-intensity (LPA), moderate-intensity (MPA), and vigorous-intensity (VPA); and the Center for Epidemiological Studies Depression Scale-10 assessed depressive symptoms. Multiple regression analysis utilizing isotemporal substitution, adjusted for relevant covariates, examined PA as predictors of depressive symptoms.Results:Substitution of 1 hour of SB with VPA resulted in a significant decrease in depressive symptoms (β = –1.215, P = .021). Similar decreases were observed when VPA replaced LPA (β = –1.212, P = .021) and MPA (β = –1.50 P = .034). MPA and LPA were not associated with lower depressive symptoms.Conclusions:Previous research has focused on the relationship of MVPA on depressive symptoms. Our results suggest these constructs should be examined separately as they may have unique relationships with depressive symptoms. The association of SB with greater depressive symptoms confirms previous reports.
Paradoxos do diagnóstico psicanalítico nos autismos
Authors: Vorcaro Angela Maria Resende 
Published: April 2017

Apresenta-se a constituição subjetiva tal como concebida por Freud e Lacan, por meio do desdobramento do nó borromea- no, na trama dos registros Real, Simbólico e Imaginário. As duas primeiras posições de cruzamento dos registros são detalhados para apresentar uma hipótese do atamento de tais registros nos autismos. Conclui-se apontando bases das operações clínicas do tratamento do autismo com os conceitos de construção e de ato em psicanálise.
Bentonitas da Formação Irati no setor sul da Bacia do Paraná
Authors: Silva Aurelio Fagundes , Dani Norberto , Remus Marcus Vinicius Dornelles , Sommer Margot Guerra , Horn Bruno Ludovico Dihl 
Published: April 2017

Este artigo tem como objetivo identificar e apresentar argumentos mineralógicos e químicos que demonstrem a existência de níveis de bentonitas inseridos na Formação Irati, em afloramentos a leste da cidade de Aceguá, sul do Rio Grande do Sul. Tratam-se de níveis com pequena espessura (em média 4 cm) e grande extensão lateral, constituídos de argilitos maciços branco-acinzentados a esverdeados que, em campo, contrastam com os folhelhos que compõem a Formação Irati. As bentonitas da Formação Irati se caracterizam por serem compostas predominantemente por Ca-montmorilonita e formam a matriz fina da rocha, na qual se encontram dispersos cristais primários, ou magmáticos, com tamanho não superior a areia muito fina. Entre os principais minerais primários identificados e representativos do ambiente vulcânico explosivo, encontram‑se pseudomorfos de β-quartzo, sanidina, biotita, zircão, apatita e ilmenita, além de fragmentos de quartzo e feldspatos (splinters). Mais raramente, encontram-se fragmentos de meso e macrocharcoals dentro das camadas de bentonita, que contrastam com a maturidade e tipo de matéria orgânica não vegetal do folhelho Irati. Com base na geoquímica da rocha e na cristaloquímica da montmorilonita neoformada nos níveis de bentonita, infere-se sobre a natureza do vulcanismo precursor. Ambas as metodologias apontam que nesse período as cinzas vulcânicas que alcançaram a Bacia do Paraná originaram-se de vulcanismo com composição intermediária, em concordância com o que é conhecido sobre as manifestações da Província Vulcânica Choiyoi Inferior, sincrônica com a sedimentação da Formação Irati na Bacia do Paraná.
Climatological Characteristics of Typical Daily Precipitation
Authors: Pendergrass Angeline G. , Deser Clara 
Published: April 2017

AbstractPrecipitation is often quantified by the amount that falls over a given period of time but not the rate at which most of it falls or the rate associated with the most frequent events. Here, three metrics are introduced to distill salient characteristics of typical daily precipitation accumulation based on the full distribution of rainfall: rain amount peak (the rain rate at which the most rain falls), rain frequency peak (the most frequent nonzero rain rate), and rain amount width (a measure of the variability of typical precipitation accumulation). These metrics are applied to two observational datasets to describe the climatology of typical daily precipitation accumulation: GPCP 1° daily (October 1996–October 2015) and TMPA 3B42 (January 1998–October 2015). Results show that the rain frequency peak is similar to total rainfall in terms of geographical pattern and seasonal cycle and varies inversely with rain amount width. In contrast, the rain amount peak varies distinctly, reaching maxima on the outer edges of the regions of high total precipitation, and with less seasonal variation. Despite that GPCP and TMPA 3B42 are both merged satellite–gauge precipitation products, they show substantial differences. In particular, the rain amount peak and rain amount width are uniformly greater in TMPA 3B42 compared to GPCP, and there are large discrepancies in their rain frequency distributions (peak and width). Issues relating to model evaluation are highlighted using CESM1 as an illustrative example and underscore the need for observational datasets incorporating measurements of light rain.
Quantifying Medical Student Education and Exposure to Otolaryngology
Authors: Wong Kevin , Jang Minyoung , Gilad Amir , Levi Jessica R. 
Published: April 2017

Objectives: Evaluate the educational and exposure opportunities provided to students by national otolaryngology organizations. Methods: Twenty-four otolaryngology organizations and subspecialty societies were reviewed for medical student involvement opportunities, educational and enrichment opportunities, costs of involvement, and available research and travel scholarships. Results: Nine organizations (37.5%) offered membership; 6 charged a membership fee, averaging $73 ± $30 (mean ± SD). Membership was limited to associate status for 7 organizations (77.8%; 7/9). Three organizations (12.5%) provided service opportunities, 4 (16.7%) allowed students to vote, and 1 (4.2%) allowed students to endorse others for membership. Most organizations allowed students to attend conferences (95.8%), and 19 (79.2%) allowed students to present research. Twenty-one (87.5%) organizations charged a conference registration fee ($366 ± $300). Seven organizations (29.2%) offered research scholarships, and 5 (20.8%) offered travel awards. Conclusions: Opportunities exist for medical students to attend conferences and present research; however, educational and enrichment activities in other areas were limited. Future efforts may be warranted to increase the number and type of opportunities for students.
Iyoite, MnCuCl(OH)3 and misakiite, Cu3Mn(OH)6Cl2: new members of the atacamite family from Sadamisaki Peninsula, Ehime Prefecture, Japan
Authors: Nishio–hamane D. , Momma K. , Ohnishi M. , Shimobayashi N. , Miyawaki R. , Tomita N. , Okuma R. , Kampf A. R. , Minakawa T. 
Published: April 2017

AbstractTwo new members of the atacamite family were discovered recently in the Sadamisaki Peninsula, Ehime Prefecture, Japan. Iyoite, MnCuCl(OH)3, is an Mn-Cu ordered analogue of botallackite, while misakiite, Cu3Mn(OH)6Cl2, is an Mn-rich analogueof kapellasite. Both minerals occur in manganese ore crevices in close association with one another. Iyoite forms radial and dendritic aggregates consisting of pale green, bladed crystals. Misakiite commonly exists in emerald green, tabular, hexagonal crystals. The densities of iyoite andmisakiite were calculated to be 3.22 and 3.42 g cm–3 based on their empirical formulae and powder X-ray diffraction data. Under the same axial setting of botallackite, iyoite is monoclinic, space group P21/m, a = 5.717(2), b = 6.586(2), c= 5.623(3) Å, β = 88.45(3)° and V = 211.63(15) Å3. Misakiite is trigonal, space group P3m1, with a = 6.4156(4), c = 5.7026(5) Å and V = 203.27(3) Å3. The structures of both mineralsare classified as layer type and the two are closely related. These new minerals were formed by the reaction between seawater and naturally-occurring manganese ores including native copper. These minerals are challenging to produce synthetically. Misakiite was synthesized successfully usinga hydrothermal method, while iyoite could not be made.
New minerals with a modular structure derived from hatrurite from the pyrometamorphic rocks. Part III. Gazeevite, BaCa6(SiO4)2(SO4)2O, from Israel and the Palestine Autonomy, South Levant, and from South Ossetia, Greater Caucasus
Authors: Galuskin E. V. , Gfeller F. , Galuskina I. O. , Armbruster T. , Krzątała A. , Vapnik Y. , Kusz J. , Dulski M. , Gardocki M. , Gurbanov A. G. , Dzierżanowski P. 
Published: April 2017

AbstractThe new mineral gazeevite, BaCa6(SiO4)2(SO4)2O (R3m,a= 7.1540(1),c= 25.1242(5) Å,V= 1113.58(3) Å3,Z= 3), was found in an altered xenolith in rhyodacites ofthe Shadil-Khokh volcano, Southern Ossetia and at three localities in larnite pyrometamorphic rocks of the Hatrurim Complex; Nahal Darga and Jabel Harmun, Judean Mountains, Palestinian Autonomy, and Har Parsa, Negev Desert, Israel. Larnite, fluorellestadite–fluorapatite, srebrodolskite–brownmilleriteand mayenite-supergroup minerals are the main minerals commonly associated with gazeevite. Gazeevite is isostructural with zadovite and aradite; the 1:1 typeAB6(TO4)2(TO4)2W, occurs together with the structurallyrelated minerals of the nabimusaite series, 3:1 type AB12(TO4)4(TO4)2W3, whereA= Ba, K, Sr...;B= Ca, Na...;T= Si, P, V5+, S6+, Al...;W= O2–,F–. Single antiperovskite layers {[WB6](TO4)2} in the structure type of gazeevite–zadovite and triple {[W3B12](TO4)4} layers in arctite–nabimusaite areintercalated with singleA(TO4) layers. These minerals with an interrupted antiperovskite structure are characterized by a modular layered structure derived from hatrurite, Ca3(SiO4)O. Gazeevite is colourless, transparent, with a white streakand vitreous lustre. Gazeevite is brittle, shows pronounced parting and imperfect cleavage on {001}; it is uniaxial (–), ω = 1.640(3), ε = 1.636(2) (λ = 589 nm) and nonpleochroic; Mohs' hardness is ∼4.5, VHN50 = 417 kg mm–2. The calculateddensity is = 3.39 g cm–3. The main lines of the calculated powder X-ray diffraction pattern are as follows (d(Å)/I/hkl): 3.58/100/110, 3.07/91/021, 2.76/47/116, 1.789/73/220, 3.29/60/113, 2.78/36/024, 2.12/25/125, 2.21/21/208. Raman spectra of gazeeviteare compared with spectra of other minerals. The formation of gazeevite and minerals of the nabimusaite–dargaite series is connected with high-temperature alteration of an early assemblage of clinker minerals affected by later fluids generated by volcanic activity or combustion processes.
DIO2 Thr92Ala Reduces Deiodinase-2 Activity and Serum-T3 Levels in Thyroid-Deficient Patients
Authors: Castagna Maria Grazia , Dentice Monica , Cantara Silvia , Ambrosio Raffaele , Maino Fabio , Porcelli Tommaso , Marzocchi Carlotta , Garbi Corrado , Pacini Furio , Salvatore Domenico 
Published: April 2017

AbstractContext:A substantial proportion of athyreotic levothyroxine (LT4)-treated patients experience hypothyroid-like symptoms. During LT4 replacement, levels of the active hormone triiodothyronine (T3) strictly depend on type 2-deiodinase (D2)-mediated activation of LT4. The Thr92Ala polymorphism and the 258 G/A in the DIO2 gene have been associated with various clinical conditions.Objectives:To investigate the effects of DIO2 polymorphisms in thyroid hormone homeostasis.Design:We compared the presurgical hormonal status of thyroidectomized LT4-treated patients who had a similar thyroid-stimulating hormone (TSH) level with their postsurgery status and analyzed their DIO2 genotype in a subgroup of 102/140 (72.8%) of patients. We measured the enzymatic properties of Thr92Ala in living cells and in relevant generated mouse models.Subjects and methods:A total of 140 thyroidectomized subjects were included. Serum free T3 (FT3), free thyroxine, and TSH levels were directly measured. Immunohistochemistry and immunoblotting were performed for D2 protein.Results:The DIO2 genotyping revealed an association between low FT3 values and Thr92Ala. Specifically, the mean postsurgery FT3 levels were significantly lower in patients carrying the mutated allele(s) than in wild-type patients, in whom FT3 postsurgical levels were similar to presurgery levels. The −258 G/A variation was not associated with hormonal alteration. We found that endogenous wild-type D2 and Thr92Ala share the same subcellular localization but differ in protein stability. Importantly, Thr92Ala reduced D2-mediated thyroxine to T3 conversion.Conclusions:Thyroidectomized patients carrying Thr92Ala are at increased risk of reduced intracellular and serum T3 concentrations that are not adequately compensated for by LT4, thus providing evidence in favor of customized treatment of hypothyroidism in athyreotic patients.
Refining Dynamic Risk Stratification and Prognostic Groups for Differentiated Thyroid Cancer With TERT Promoter Mutations
Authors: Kim Tae Hyuk , Ki Chang-Seok , Kim Hye Seung , Kim Kyunga , Choe Jun-Ho , Kim Jung-Han , Kim Jee Soo , Oh Young Lyun , Hahn Soo Yeon , Shin Jung Hee , Jang Hye Won , Kim Sun Wook , Chung Jae Hoon 
Published: April 2017

Abstract

Context:
Currently, no recurrence or mortality risk systems consider molecular testing when predicting thyroid cancer outcomes.

Objective:
We developed an integrative prognostic system that incorporates telomerase reverse transcription (TERT) promoter mutations into the recently proposed risk reclassification system after initial therapy [dynamic risk stratification (DRS)] to better categorize and predict outcomes.

Design:
A total of 357 differentiated thyroid cancer (DTC) patients without initial distant metastasis were enrolled. Among patients with mutated TERT and wild-type, recurrence-free survival (RFS) was compared according to DRS grouping. Cox regression was used to calculate adjusted hazard ratios (AHRs) to derive AHR groups. Performance of the AHR grouping system with respect to prediction of structural recurrence and cancer-specific survival (CSS) was assessed against the current DRS system and the tumor/node/metastasis (TNM) classification.

Results:
Among 357 patients, there were 90 recurrences and 15 cancer-related deaths during a median of 14 years of follow-up. Patients in higher AHR groups were at higher risk of recurrence (10-year RFS for AHR 1, 2, 3, and 4: 94.9%, 82.7%, 50.2%, and 23.1%; P &lt; 0.001) and cancer-related death (10-year CSS: 100.0%. 98.7%, 94.2%, and 76.9%; P &lt; 0.001). The proportions of variance explained (PVEs) for the ability of AHR and DRS grouping to predict recurrence were 22.4% and 18.5%. PVEs of AHR and TNM system to predict cancer-related deaths were 11.5% and 7.4%.

Conclusions:
The AHR grouping system, a simple two-dimensional prognostic system, is as effective as DRS at predicting structural recurrence and provides clinical implication for long-term CSS in patients with nonmetastatic DTC.
Sex Steroid Hormones and Fracture in a Multiethnic Cohort of Women: The Women’s Health Initiative Study (WHI)
Authors: Cauley Jane A. , Danielson Michelle E. , Jammy Guru Rajesh , Bauer Doug C. , Jackson Rebecca , Wactawski-Wende Jean , Chlebowski Rowan T. , Ensrud Kristine E. , Boudreau Robert 
Published: April 2017

Abstract

Context:
We hypothesize that endogenous sex steroids are associated with fracture risk independent of race/ethnicity.

Design and Setting:
We performed a nested case-control study within the prospective Women’s Health Initiative Observational Study. Incident nonspine fractures were identified in 381 black, 192 Hispanic, 112 Asian, and 46 Native American women over an average of 8.6 years. A random sample of 400 white women who experienced an incident fracture was chosen. One control was selected per case and matched on age, race/ethnicity, and blood draw date. Bioavailable estradiol (BioE2), bioavailable testosterone (BioT), and sex hormone–binding globulin (SHBG) were measured using baseline fasting serum. Conditional logistic regression models calculated the odds ratio (OR) and 95% confidence interval (CI) of fracture across tertiles of hormone.

Results:
In multivariable and race/ethnicity-adjusted models, higher BioE2 (&gt;8.25 pg/mL) and higher BioT (&gt;13.3 ng/dL) were associated with decreased risk of fracture (OR, 0.65; 95% CI, 0.50 to 0.85; P trend = 0.001 and OR, 0.76; 95% CI, 0.60 to 0.96; P trend = 0.02, respectively). The interaction term between race/ethnicity and either BioE2 or BioT was not significant. There was no association between SHBG and fracture risk. In models stratifying by race/ethnicity, higher BioE2 was associated with a lower risk of fracture in both white women (OR, 0.56; 95% CI, 0.36 to 0.87) and black women (OR, 0.61; 95% CI, 0.39 to 0.96). Higher BioT was associated with a significantly lower fracture risk in only black women (OR, 0.65; 95% CI, 0.43 to 1.00), P trend = 0.03.

Conclusions:
Serum BioE2 and BioT are associated with fracture risk in older women irrespective of race/ethnicity and independent of established risk factors for fracture.