bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multichannel Charge Transfer and Mechanistic Insight in Metal Decorated 2D–2D Bi2WO6–TiO2 Cascade with Enhanced Photocatalytic Performance
Authors: Yuan Lan , Weng Bo , Colmenares Juan Carlos , Sun Yugang , Xu Yi‐Jun 
Published: October 2017

AbstractPromising semiconductor‐based photocatalysis toward achieving efficient solar‐to‐chemical energy conversion is an ideal strategy in response to the growing worldwide energy crisis, which however is often practically limited by the insufficient photoinduced charge‐carrier separation. Here, a rational cascade engineering of Au nanoparticles (NPs) decorated 2D/2D Bi2WO6–TiO2 (B–T) binanosheets to foster the photocatalytic efficiency through the manipulated flow of multichannel‐enhanced charge‐carrier separation and transfer is reported. Mechanistic characterizations and control experiments, in combination with comparative studies over plasmonic Au/Ag NPs and nonplasmonic Pt NPs decorated 2D/2D B–T composites, together demonstrate the cooperative synergy effect of multiple charge‐carrier transfer channels in such binanosheets‐based ternary composites, including Z‐scheme charge transfer, “electron sink,” and surface plasmon resonance effect, which integratively leads to the boosted photocatalytic performance.
Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair
Authors: Martella Daniele , Paoli Paolo , Pioner Josè M. , Sacconi Leonardo , Coppini Raffaele , Santini Lorenzo , Lulli Matteo , Cerbai Elisabetta , Wiersma Diederik S. , Poggesi Corrado , Ferrantini Cecilia , Parmeggiani Camilla 
Published: October 2017

AbstractThe communication reports the use of liquid crystalline networks (LCNs) for engineering tissue cultures with human cells. Their ability as cell scaffolds for different cell lines is demonstrated. Preliminary assessments of the material biocompatibility are performed on human dermal fibroblasts and murine muscle cells (C2C12), demonstrating that coatings or other treatments are not needed to use the acrylate‐based materials as support. Moreover, it is found that adherent C2C12 cells undergo differentiation, forming multinucleated myotubes, which show the typical elongated shape, and contain bundles of stress fibers. Once biocompatibility is demonstrated, the same LCN films are used as a substrate for culturing human induced pluripotent stem cell‐derived cardiomyocites (hiPSC‐CMs) proving that LCNs are capable to develop adult‐like dimensions and a more mature cell function in a short period of culture in respect to standard supports. The demonstrated biocompatibility together with the extraordinary features of LCNs opens to preparation of complex cell scaffolds, both patterned and stimulated, for dynamic cell culturing. The ability of these materials to improve cell maturation and differentiation will be developed toward engineered heart and skeletal muscular tissues exploring regenerative medicine toward bioartificial muscles for injured sites replacement.
Cross-Tissue Identification of Somatic Stem and Progenitor Cells Using a Single-Cell RNA-Sequencing Derived Gene Signature
Authors: Schwalie Petra C. , Ordóñez-Morán Paloma , Huelsken Joerg , Deplancke Bart 
Published: October 2017

Abstract
A long-standing question in biology is whether multipotent somatic stem and progenitor cells (SSPCs) feature molecular properties that could guide their system-independent identification. Population-based transcriptomic studies have so far not been able to provide a definite answer, given the rarity and heterogeneous nature of these cells. Here, we exploited the resolving power of single-cell RNA-sequencing to develop a computational model that is able to accurately distinguish SSPCs from differentiated cells across tissues. The resulting classifier is based on the combined expression of 23 genes including known players in multipotency, proliferation, and tumorigenesis, as well as novel ones, such as Lcp1 and Vgll4 that we functionally validate in intestinal organoids. We show how this approach enables the identification of stem-like cells in still ambiguous systems such as the pancreas and the epidermis as well as the exploration of lineage commitment hierarchies, thus facilitating the study of biological processes such as cellular differentiation, tissue regeneration, and cancer.
Sox2 Communicates with Tregs Through CCL1 to Promote the Stemness Property of Breast Cancer Cells
Authors: Xu Yingxi , Dong Xiaoli , Qi Pingping , Ye Yujie , Shen Wenzhi , Leng Liang , Wang Lina , Li Xuefei , Luo Xiaohe , Chen Yanan , Sun Peiqing , Xiang Rong , Li Na 
Published: October 2017

Abstract
As an important component of the tumor microenvironment, CD4+CD25+ Tregs reduce antitumor immunity, promote angiogenesis and metastasis in breast cancer. However, their function in regulating the “stemness” of tumor cells and the communication between Tregs and cancer stem cells (CSCs) remain elusive. Here, we disclose that the primarily cultured Tregs isolated from breast-tumor-bearing Foxp3-EGFP mouse upregulate the stemness property of breast cancer cells. Tregs increased the side-population and the Aldehyde dehydrogenase-bright population of mouse breast cancer cells, promoted their sphere formation in a paracrine manner, and enhanced the expression of stemness genes, such as Sox2 and so forth. In addition, Tregs increased tumorigenesis, metastasis, and chemoresistance of breast cancer cells. Furthermore, Sox2-overexpression tumor cells activated NF-κB-CCL1 signaling to recruit Tregs through reducing the binding of H3K27Me3 on promoter regions of p65 and Ccl1. These findings reveal the functional interaction between Tregs and CSCs and indicate that targeting on the communication between them is a promising strategy in breast cancer therapy.
Mouse Parthenogenetic Embryonic Stem Cells with Biparental-Like Expression of Imprinted Genes Generate Cortical-Like Neurons That Integrate into the Injured Adult Cerebral Cortex
Authors: Varrault Annie , Eckardt Sigrid , Girard Benoît , Le Digarcher Anne , Sassetti Isabelle , Meusnier Céline , Ripoll Chantal , Badalyan Armen , Bertaso Federica , McLaughlin K. John , Journot Laurent , Bouschet Tristan 
Published: October 2017

Abstract
One strategy for stem cell-based therapy of the cerebral cortex involves the generation and transplantation of functional, histocompatible cortical-like neurons from embryonic stem cells (ESCs). Diploid parthenogenetic Pg-ESCs have recently emerged as a promising source of histocompatible ESC derivatives for organ regeneration but their utility for cerebral cortex therapy is unknown. A major concern with Pg-ESCs is genomic imprinting. In contrast with biparental Bp-ESCs derived from fertilized oocytes, Pg-ESCs harbor two maternal genomes but no sperm-derived genome. Pg-ESCs are therefore expected to have aberrant expression levels of maternally expressed (MEGs) and paternally expressed (PEGs) imprinted genes. Given the roles of imprinted genes in brain development, tissue homeostasis and cancer, their deregulation in Pg-ESCs might be incompatible with therapy. Here, we report that, unexpectedly, only one gene out of 7 MEGs and 12 PEGs was differentially expressed between Pg-ESCs and Bp-ESCs while 13 were differentially expressed between androgenetic Ag-ESCs and Bp-ESCs, indicating that Pg-ESCs but not Ag-ESCs, have a Bp-like imprinting compatible with therapy. In vitro, Pg-ESCs generated cortical-like progenitors and electrophysiologically active glutamatergic neurons that maintained the Bp-like expression levels for most imprinted genes. In vivo, Pg-ESCs participated to the cortical lineage in fetal chimeras. Finally, transplanted Pg-ESC derivatives integrated into the injured adult cortex and sent axonal projections in the host brain. In conclusion, mouse Pg-ESCs generate functional cortical-like neurons with Bp-like imprinting and their derivatives properly integrate into both the embryonic cortex and the injured adult cortex. Collectively, our data support the utility of Pg-ESCs for cortical therapy.
Morphological diversity of panicle traits in Kam fragrant glutinous rice (Oryza sativa)
Authors: Lei Qiyi , Zhou Jiangju , Zhang Wenhua , Luo Jing , Wu Kainian , Long Chunlin 
Published: October 2017

Abstract
Panicle traits are the most intuitive and representative features of rice germplasm resources that have been utilized in the determination of its identity, genetic diversity, yield, and quality. Based on the approaches of ethnobotany, cultural anthropology and plant morphology, we analyzed the panicle traits of 95 traditional Kam fragrant glutinous rice landraces according to folk classification in Qiandongnan Prefecture of Guizhou Province in the past 10 years. A total of 95 Kam fragrant glutinous rice landraces were tested, of which 91% consisted of those with awns, and landraces with awn lengths of 2–6 cm comprised 62%. The coefficient of variation (CV) of awn color, husk color and Grain color was more than 50%, thereby indicating extensive morphological variations among the traditional Kam fragrant glutinous rice landraces. The average Shannon–Wiener value (diversity index, H′) for panicle qualitative traits was 0.50, which was significantly higher than that of quantitative traits (0.22), thereby indicating a relatively higher degree of genetic diversity among qualitative traits. Cluster analysis of panicle morphological traits showed that 95 Kam fragrant glutinous rice landraces could be divided into five categories, using the Euclidean distance of 0.68 as threshold. Each cultivar manifested unique panicle traits. The present study on the morphological diversity of Kam fragrant glutinous rice landraces provided basic information that may be utilized for the conservation and sustainable use of Kam fragrant glutinous rice landraces.
How to become a first mover? Mechanisms of military innovation and the development of drones
Authors: Weiss Moritz 
Published: October 2017

AbstractStates generate the hardware of military power by either developing new technologies as first mover or adopting demonstrated technology as second mover. Given that military drones have arguably demonstrated effectiveness and thus proliferate, scholars have produced profound insights into today’s second mover dynamics. Yet, the preceding political process of developing this military technology remains poorly understood. The article’s objective is to explain how states become first movers of military hardware. To this end, it applies four causal mechanisms of military innovation studies to the historical trajectory of the development of drones. I argue that security threats initially formed state interests in drones. Yet, capacity was necessary for success. Politically induced transfers and cross-sector diffusion supplied technological progress. At the same time, distributional implications and legacy systems constrained the development process, but could ultimately be overcome. This mechanismic pathway results from the process-tracing analysis of two separate, but related trajectories in Israel and the United States since the 1970s. Given within-case variation, a sequencing and domain-of-application perspective allows the formulation of scope conditions of the mechanisms behind military innovation. This contributes to a historically contingent, yet generalisable, understanding of the political process of how states generate military power.
JAMAICAN LEGISLATION AND THE TRANSATLANTIC CONSTITUTION, 1664–1839
Authors: GRAHAM AARON 
Published: October 2017

AbstractBetween its first meeting in January 1664 and the final session held under unfree labour in December 1838, the volume of legislation passed by the house of assembly in Jamaica increased exponentially. As in Britain and Ireland, this reflected the growing administrative capacity and political power of the legislature and also the enormous demand for laws and law-making among local interest groups. The rise and fall of slavery and the slave society in the island was therefore underpinned in a large part by the power of its colonial legislature, which also operated within the broader transatlantic constitution structured by imperial politics and law. There was very little though to distinguish the house of assembly from others in British North America, at least in legislative terms, and even after the traumatic imperial disjuncture of 1783 the reformed transatlantic constitution continued to provide a supportive environment for the expansion of legislation within the island of Jamaica.
Molecular and morphological characterization of Belondira coomansi n. sp. (Nematoda: Dorylaimida, Belondiridae) from Iran
Authors: Golhasan B. , Heydari R. , Miraeiz E. , Abolafia J. , Peña-Santiago R. 
Published: October 2017

AbstractA new species belonging to the genus Belondira is described from natural areas in Iran. Belondira coomansi n. sp. is characterized by its general size, the dimensions and appearance of its lip region, presence of distinct labial and post-labial sclerotization, the length of the odontostyle and its inconspicuous lumen and aperture, the length of the neck and its pharyngeal expansion, the reduction of the female anterior genital branch to a simple uterine sac, a very short posterior uterus, the anterior position of the vulva, the length and shape of the caudal region with distinctly thick cuticle at its tip, the length of the spicules, and the presence of only one pair of ventromedian supplements. The new species is close to Belondira brevibulba, B. sacchari, B. tenuidens and B. thornei, and it is compared to them. Molecular characterization (D2–D3 expansion segments of the rRNA large subunit) of the new species is also provided, representing only the second species of this genus for which any DNA sequence data are available.
Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis
Authors: Sahin E , Dizdar D , Dinc M E , Cirik A A 
Published: October 2017

AbstractBackground:Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.Methods:The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).Results:The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p< 0.0175). There were no significant differences between the scores obtained at 3 years and 10 years after allergen-specific immunotherapy (p> 0.0175).Conclusion:Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.
Capitalism, Jacobinism and International Relations: Re-interpreting the Ottoman path to modernity
Authors: Duzgun Eren 
Published: October 2017

AbstractDebates over ‘modernity’ have been central to the development of historical-sociological approaches to International Relations (IR). Within the bourgeoning subfield of International Historical Sociology (IHS), much work has been done to formulate a historically dynamic conception of international relations, which is then used to undermine unilinear conceptions of global modernity. Nevertheless, this article argues that IHS has not proceeded far enough in successfully remedying the problem of unilinearism. The problem remains that historical narratives, informed by IHS, tend to transhistoricise capitalism, which, in turn, obscures the generative nature of international relations, as well as the fundamental heterogeneity of diverging paths to modernity both within and beyond western Europe. Based on the theory of Uneven and Combined Development, Political Marxism, and Robbie Shilliam’s discussion of ‘Jacobinism’, this article first reinterprets the radical multilinearity of modernity within western Europe, and then utilises this reinterpretation to provide a new reading of the Ottoman path to modernity (1839–1918). Such a historical critique and reconstruction will highlight the significance of Jacobinism for a more accurate theorisation of the origin and development of the modern international order, hence contributing to a deeper understanding of the international relations of modernity.
DIFFERENCES IN VISUAL WORD RECOGNITION BETWEEN L1 AND L2 SPEAKERS
Authors: Schröter Pauline , Schroeder Sascha 
Published: October 2017

AbstractInvestigating the impact of linguistic characteristics on visual word recognition in children, we studied whether differences in native (L1) and second language (L2) processing already emerge at the beginning of reading development. German elementary school students in grades 2 to 6 completed a battery of standardized tests and a lexical decision task (LDT). Though L1 speakers outperformed L2 speakers on German skills, groups did not differ in their overall performance on the LDT. However, results from mixed-effect models revealed greater effects for word frequency and length in L2 over L1 speakers, indicating qualitative differences in the sensitivity to linguistic information between groups. This distinction persisted across all grades and after controlling for differences in vocabulary size and reading fluency. Findings extend evidence provided for adult L2 processing, suggesting that varying language exposure shapes the development of the word-recognition system already in the early stages of reading development.
Determinants of takeaway and fast food consumption: a narrative review
Authors: Janssen Hayley G. , Davies Ian G. , Richardson Lucinda D. , Stevenson Leonard 
Published: October 2017

AbstractOut-of-home foods (takeaway, take-out and fast foods) have become increasingly popular in recent decades and are thought to be a key driver in increasing levels of overweight and obesity due to their unfavourable nutritional content. Individual food choices and eating behaviours are influenced by many interrelated factors which affect the results of nutrition-related public health interventions. While the majority of research based on out-of-home foods comes from Australia, the UK and USA, the same issues (poor dietary habits and increased prevalence of non-communicable disease) are of equal concern for urban centres in developing economies undergoing ‘nutrition transition’ at a global scale. The present narrative review documents key facets, which may influence out-of-home food consumption, drawn from biological, societal, environmental, demographic and psychological spheres. Literature searches were performed and references from relevant papers were used to find supplementary studies. Findings suggest that the strongest determinants of out-of-home food availability are density of food outlets and deprivation within the built environment; however, the association between socio-economic status and out-of-home food consumption has been challenged. In addition, the biological and psychological drives combined with a culture where overweight and obesity are becoming the norm makes it ‘fashionable’ to consume out-of-home food. Other factors, including age group, ethnicity and gender demonstrate contrasting effects and a lack of consensus. It is concluded that further consideration of the determinants of out-of-home food consumption within specific populations is crucial to inform the development of targeted interventions to reduce the impact of out-of-home foods on public health.
The effects of spatial survey bias and habitat suitability on predicting the distribution of threatened species living in remote areas
Authors: CARDADOR LAURA , DÍAZ-LUQUE JOSÉ A. , HIRALDO FERNANDO , GILARDI JAMES D. , TELLA JOSÉ L. 
Published: October 2017

SummaryKnowledge of a species’ potential distribution and the suitability of available habitat are fundamental for effective conservation planning and management. However, the quality of information on the distribution of species and their required habitats is highly variable in terms of accuracy and availability across taxa and regions, particularly in tropical landscapes where accessibility is especially challenging. Species distribution models (SDMs) provide predictive tools for addressing gaps for poorly surveyed species, but they rarely consider biases in geographical distribution of records and their consequences. We applied SDMs and variation partitioning analyses to investigate the relative importance of habitat characteristics, human accessibility, and their joint effects in the global distribution of the Critically Endangered Blue-throated MacawAra glaucogularis, a species endemic to the Amazonian flooded savannas of Bolivia. The probability of occurrence was skewed towards more accessible areas, mostly secondary roads. Variability in observed occurrence patterns was mostly accounted for by the pure effect of habitat characteristics (76.2%), indicating that bias in the geographical distribution of occurrences does not invalidate species-habitat relationships derived from niche models. However, observed spatial covariation between land-use at a landscape scale and accessibility (joint contribution: 22.3%) may confound the independent role of land-use in the species distribution. New surveys should prioritise collecting data in more remote (less accessible) areas better distributed with respect to land-use composition at a landscape scale. Our results encourage wider application of partitioning methods to quantify the extent of sampling bias in datasets used in habitat modelling for a better understanding of species-habitat relationships, and add insights into the potential distribution of our study species and opportunities for its conservation.
Intergenerational transmission of family meal patterns from adolescence to parenthood: longitudinal associations with parents’ dietary intake, weight-related behaviours and psychosocial well-being
Authors: Berge Jerica M , Miller Jonathan , Watts Allison , Larson Nicole , Loth Katie A , Neumark-Sztainer Dianne 
Published: October 2017

AbstractObjectiveThe present study examined longitudinal associations between four family meal patterns (i.e. never had regular family meals, started having regular family meals, stopped having regular family meals, maintained having regular family meals) and young adult parents’ dietary intake, weight-related behaviours and psychosocial well-being. In addition, family meal patterns of parents were compared with those of non-parents.DesignAnalysis of data from the longitudinal Project EAT (Eating and Activity in Adolescents and Young Adults) study. Linear and logistic regressions were used to examine the associations between family meal patterns and parents’ dietary intake, weight-related behaviours and psychosocial well-being.SettingSchool and in-home settings.SubjectsAt baseline (1998; EAT-I), adolescents (n 4746) from socio-economically and racially/ethnically diverse households completed a survey and anthropometric measurements at school. At follow-up (2015; EAT-IV), participants who were parents (n 726) and who were non-parents with significant others (n 618) completed an online survey.ResultsYoung adult parents who reported having regular family meals as an adolescent and as a parent (‘maintainers’), or who started having regular family meals with their own families (‘starters’), reported more healthful dietary, weight-related and psychosocial outcomes compared with young adults who never reported having regular family meals (‘nevers’; P<0·05). In addition, parents were more likely to be family meal starters than non-parents.ConclusionsResults suggest that mental and physical health benefits of having regular family meals may be realized as a parent whether the routine of regular family meals is carried forward from adolescence into parenthood, or if the routine is started in parenthood.