bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient Evaluation of Emotional Comfort Experienced (PEECE): developing and testing a measurement instrument
Authors: Williams A M , Lester L , Bulsara C , Petterson A , Bennett K , Allen E , Joske D 
Published: January 2017

ObjectivesThePatientEvaluation ofEmotionalComfortExperienced (PEECE) is a 12-item questionnaire which measures the mental well-being state of emotional comfort in patients. The instrument was developed using previous qualitative work and published literature.DesignInstrument development.SettingAcute Care Public Hospital, Western Australia.ParticipantsSample of 374 patients.InterventionsA multidisciplinary expert panel assessed the face and content validity of the instrument and following a pilot study, the psychometric properties of the instrument were explored.Main outcome measuresExploratory and confirmatory factor analysis assessed the underlying dimensions of the PEECE instrument; Cronbach's α was used to determine the reliability; κ was used for test–retest reliability of the ordinal items.Results2 factors were identified in the instrument and named ‘positive emotions’ and ‘perceived meaning’. A greater proportion of male patients were found to report positive emotions compared with female patients. The instrument was found to be feasible, reliable and valid for use with inpatients and outpatients.ConclusionsPEECE was found to be a feasible instrument for use with inpatient and outpatients, being easily understood and completed. Further psychometric testing is recommended.
Study of connectivity of open framework gravel facies in the Canterbury Plains aquifer using smoke as a tracer
Authors: Burbery Lee F. , Moore Catherine R. , Jones Merren A. , Abraham Phillip M. , Humphries Bronwyn L. , Close Murray E. 
Published: January 2017

Abstract
Open framework gravels (OFGs) are an inherent textural component of alluvial gravel outwash deposited by braided river systems. Being exceptionally permeable, they play an important part in facilitating the transmission of water and contaminants through alluvial gravel aquifers. Understanding how connected OFG facies are is helpful in making informed predictions about groundwater flow and contaminant transport through such aquifer systems. This work examined a section of the Rakaia fan, Canterbury, New Zealand. A 3 × 3 grid of large diameter auger holes was drilled in close proximity to a sea cliff, which provided very good three-dimensional exposure of the fan architecture. A novel smoke tracing experiment and water tracing field tests were conducted to measure the dynamic connectivity of the OFG facies. Smoke proved to be an effective tracer for measuring the interconnectedness of OFGs over set distances of 5 m. The water tracing tests confirmed that OFGs are connected across much longer distances – in excess of 18 m. Results from both tests revealed how rapid, and non-uniform, aqueous transport can be through alluvial outwash materials. The connectivity information will be used to improve realizations of the heterogeneity of the Canterbury Plains aquifer and inform future hydrogeological modelling.
The Genetic Basis of Hepatosplenic T-cell Lymphoma
Authors: McKinney Matthew , Moffitt Andrea B. , Gaulard Philippe , Travert Marion , De Leval Laurence , Nicolae Alina , Raffeld Mark , Jaffe Elaine S. , Pittaluga Stefania , Xi Liqiang , Heavican Tayla , Iqbal Javeed , Belhadj Karim , Delfau-Larue Marie Helene , Fataccioli Virginie , Czader Magdalena B. , Lossos Izidore S. , Chapman-Fredricks Jennifer R. , Richards Kristy L. , Fedoriw Yuri , Ondrejka Sarah L. , Hsi Eric D. , Low Lawrence , Weisenburger Dennis , Chan Wing C. , Mehta-Shah Neha , Horwitz Steven , Bernal-Mizrachi Leon , Flowers Christopher R. , Beaven Anne W. , Parihar Mayur , Baseggio Lucile , Parrens Marie , Moreau Anne , Sujobert Pierre , Pilichowska Monika , Evens Andrew M. , Chadburn Amy , Au-Yeung Rex K.H. , Srivastava Gopesh , Choi William W. L. , Goodlad John R. , Aurer Igor , Basic-Kinda Sandra , Gascoyne Randy D. , Davis Nicholas S. , Li Guojie , Zhang Jenny , Rajagopalan Deepthi , Reddy Anupama , Love Cassandra , Levy Shawn , Zhuang Yuan , Datta Jyotishka , Dunson David B. , Davé Sandeep S. 
Published: January 2017

Abstract
Hepatosplenic T-cell lymphoma (HSTL) is a rare and lethal lymphoma; the genetic drivers of this disease are unknown. Through whole-exome sequencing of 68 HSTLs, we define recurrently mutated driver genes and copy-number alterations in the disease. Chromatin-modifying genes, including SETD2, INO80, and ARID1B, were commonly mutated in HSTL, affecting 62% of cases. HSTLs manifest frequent mutations in STAT5B (31%), STAT3 (9%), and PIK3CD (9%), for which there currently exist potential targeted therapies. In addition, we noted less frequent events in EZH2, KRAS, and TP53. SETD2 was the most frequently silenced gene in HSTL. We experimentally demonstrated that SETD2 acts as a tumor suppressor gene. In addition, we found that mutations in STAT5B and PIK3CD activate critical signaling pathways important to cell survival in HSTL. Our work thus defines the genetic landscape of HSTL and implicates gene mutations linked to HSTL pathogenesis and potential treatment targets.
Significance: We report the first systematic application of whole-exome sequencing to define the genetic basis of HSTL, a rare but lethal disease. Our work defines SETD2 as a tumor suppressor gene in HSTL and implicates genes including INO80 and PIK3CD in the disease. Cancer Discov; 7(4); 369–79. ©2017 AACR.
See related commentary by Yoshida and Weinstock, p. 352.
This article is highlighted in the In This Issue feature, p. 339
<b>Incipient loss of a rainforest mutualism?</b>
Authors: Fischer Johannes H. , Wittmer Heiko U. , Setiawan Endro , Jaffe Sarah , Marshall Andrew J. 
Published: January 2017

We use data from motion-activated remote cameras to document a commensal, and possibly mutualistic, relationship between Bornean Ground Cuckoos and Bearded Pigs in the rainforests of Kalimantan, Indonesia. We hypothesise that birds benefiting from symbiotic relationships may suffer indirect detrimental effects from hunting that targets large mammals in tropical rainforests.
<b>First record of Rusty-spotted Cat <I>Prionailurus rubiginosus</I> (Mammalia: Carnivora: Felidae) from Ramgarh-Vishdhari Wildlife Sanctuary in semi-arid landscape of Rajasthan, India</b>
Authors: Nayak Sailaja , Shah Sunny , Borah Jimmy 
Published: January 2017

Restricted to India and Sri Lanka in its distribution, the Rusty-spotted Cat <I>Prionailurus rubiginosus</I> is the smallest felid in the world. The present distribution of this species in India is to a large extent not thoroughly documented and is based on opportunistic sightings and reports. To date, the northernmost confirmed record of this cat is from Sariska and Ranthambhore Tiger Reserve. In this communication, we present evidence of this species from further south at Ramgarh-Vishdhari Wildlife Sanctuary from the state of Rajasthan.
Risk of Cerebrovascular Events in 178 962 Five-Year Survivors of Cancer Diagnosed at 15 to 39 Years of Age
Authors: Bright Chloe J. , Hawkins Mike M. , Guha Joyeeta , Henson Katherine E. , Winter David L. , Kelly Julie S. , Feltbower Richard G. , Hall Marlous , Cutter David J. , Edgar Angela B. , Frobisher Clare , Reulen Raoul C. 
Published: January 2017

Background:
Survivors of teenage and young adult cancer are at risk of cerebrovascular events, but the magnitude of and extent to which this risk varies by cancer type, decade of diagnosis, age at diagnosis, and attained age remains uncertain. This is the largest-ever cohort study to evaluate the risks of hospitalization for a cerebrovascular event among long-term survivors of teenage and young adult cancer.

Methods:
The population-based TYACSS (Teenage and Young Adult Cancer Survivor Study) (N=178,962) was linked to Hospital Episode Statistics data for England to investigate the risks of hospitalization for a cerebrovascular event among 5-year survivors of cancer diagnosed when 15 to 39 years of age. Observed numbers of first hospitalizations for cerebrovascular events were compared with that expected from the general population using standardized hospitalization ratios (SHRs) and absolute excess risks per 10 000 person-years. Cumulative incidence was calculated with death considered a competing risk.

Results:
Overall, 2782 cancer survivors were hospitalized for a cerebrovascular event—40% higher than expected (SHR=1.4, 95% confidence interval, 1.3–1.4). Survivors of central nervous system (CNS) tumors (SHR=4.6, 95% confidence interval, 4.3–5.0), head and neck tumors (SHR=2.6, 95% confidence interval, 2.2–3.1), and leukemia (SHR=2.5, 95% confidence interval, 1.9–3.1) were at greatest risk. Males had significantly higher absolute excess risks than females (absolute excess risks =7 versus 3), especially among head and neck tumor survivors (absolute excess risks =30 versus 11). By 60 years of age, 9%, 6%, and 5% of CNS tumor, head and neck tumor, and leukemia survivors, respectively, had been hospitalized for a cerebrovascular event. Beyond 60 years of age, every year, 0.4% of CNS tumor survivors were hospitalized for a cerebral infarction (versus 0.1% expected), whereas at any age, every year, 0.2% of head and neck tumor survivors were hospitalized for a cerebral infarction (versus 0.06% expected).

Conclusions:
Survivors of a CNS tumor, head and neck tumor, and leukemia are particularly at risk of hospitalization for a cerebrovascular event. The excess risk of cerebral infarction among CNS tumor survivors increases with attained age. For head and neck tumor survivors, this excess risk remains high across all ages. These groups of survivors, particularly males, should be considered for surveillance of cerebrovascular risk factors and potential pharmacological interventions for cerebral infarction prevention.
Contribution of Tropical Cyclones to Rainfall in the Philippines
Authors: Bagtasa Gerry 
Published: January 2017

AbstractTropical cyclone (TC)-induced rainfall (TC rain) in the Philippines was investigated using a combination of ground and satellite observations to produce a blended 64-yr precipitation dataset. A total of 1673 TCs were examined using best track data from the Japan Meteorological Agency. Rainfall from 100 (~1110 km) of the TC center was considered as TC-induced rainfall. TC rain contribution is highest in the northern Philippines, particularly along the western coast of Luzon (up to 54%), and lowest in the southern islands of Mindanao (6%). The high TC rain contribution is attributed to the enhancement of the Asian southwest monsoon by TCs located to the northeast of the Philippines. An unsupervised clustering method, k-means clustering, was used to divide the archipelago into four climate subtypes according to monthly rainfall variation. Interannual variability of rainfall from climate clusters with high TC rain contribution generally follows the variability of TC rain. On the other hand, the variability of low TC rain clusters is mainly influenced by El Niño–Southern Oscillation (ENSO). All clusters show increasing trends of 16.9%–19.3% decade−1 in TC rain percentage contribution since 2000. This study hypothesizes that this increasing trend is due to changes in the characteristics of TC steering mechanisms and thermodynamic properties east of the Philippines in the past one and a half decades.
A 10-Year Austral Summer Climatology of Observed and Modeled Intraseasonal, Mesoscale, and Diurnal Variations over the Maritime Continent
Authors: Vincent Claire L. , Lane Todd P. 
Published: January 2017

Abstract
The Maritime Continent is one of the wettest regions on the planet and has been shown to be important for global budgets of heat and moisture. Convection in the region, however, varies on several interrelated scales, making it difficult to quantify the precipitation climate and understand the key processes. For example, the diurnal cycle in precipitation over the land varies substantially according to the phase of the Madden–Julian oscillation (MJO), and the diurnal precipitation cycle over the water is coupled to that over the land, in some cases for distances of over 1000 km from the coast.
Here, a 10-yr austral summer climatology of diurnal and MJO-scale variations in rain rate over the land and sea over the Maritime Continent is presented. The climatology is based on mesoscale model simulations with a horizontal grid length of 4 km and satellite precipitation estimates. The amplitude of the observed diurnal precipitation cycle is shown to reach a maximum just prior to the MJO active phase, with a weaker secondary maximum after the MJO active phase. Although these two maxima also exist in the modeled diurnal precipitation cycle, there is less difference between the maxima before and after the MJO active phase than in the observations. The modeled sea-breeze circulation is also shown to possess approximately equal maxima just before and just after the MJO active period, suggesting that the asymmetry of the diurnal precipitation cycle about the MJO active period is related more to moisture availability than kinematic forcing.
Application of A Spreadsheet Program to Control System Design
Authors: Wong Yiu-Kwong 
Published: January 2017

Application of a spreadsheet program to control system design The Symphony spreadsheet program is applied to calculate the frequency response of feedback control systems. A design template which contains the necessary formulae was constructed so that very little knowledge of the program is required to obtain impressive results. The template becomes a powerful tool by providing a fast and efficient means of designing a stable closed-loop system as well as predicting its performance.
Progress of Direct Entry Students on Year 2 B. Eng. Honours Course in Electronic Engineering at Middlesex University
Authors: Fewson D. 
Published: January 2017

Progress of direct entry students on Year 2, BEng Honours course in Electronic Engineering at Middlesex University Transfer of students with good Electronic HNDs into the second year of an Electronic BEng Honours course has proved to be very successful. These students compare very well with those of more conventional entry, and many achieve high honours awards at the end of the course.
Motivating Engineering Undergraduates with Practical Problems
Authors: Ng Lian-Soon , Tan Ooi-Kiang , Jong Ching-Chuen 
Published: January 2017

Motivating engineering undergraduates with practical problems In this paper, a nine-hour practical session suitable for second-year engineering undergraduates is proposed and discussed. The aims and objectives of the practical session, as well as the tasks for the students are clearly formulated. The domains of each task are analysed. The existing practices are reflected and reviewed and a new assessment scheme is proposed.
Enticing Students to Program Microcontrollers
Authors: Haysom M. L. 
Published: January 2017

Enticing students to program microcontrollers Writing microcontroller code requires the application of logic and defined rules. It may have intrinsic appeal to some people, but not to others. This paper presents a strategy which successfully enticed a diverse group of students to program microcontrollers. The strategy is consistent with industrial techniques for microcontroller system development.
Protecting CAD Files During Development: The Sunos SCCS System
Authors: Noras James M. 
Published: January 2017

Protecting CAD files during development: the SunOS SCCS system This is a practical introduction to the Source Code Control System (SCCS) for the development and protection of text-files. Familiar in software projects, it can be a valuable aid for CAD using textual hardware description. A Verilog example illustrates the method, and then the system's most useful features are explained.
Programmable Nonlinear Adc: An Illustrative Example
Authors: Anvekar Dinesh K. , Sonde B. S. 
Published: January 2017

Programmable nonlinear ADC: an illustrative example Programmable nonlinear analog-to-digital conversion is a new topic in EE curricula. With a view to introducing the EE student to the concept of transfer characteristic programmability of an analog-to-digital converter (ADC), a memory-prefetch programmable nonlinear ADC is presented. The design, analytical evaluation, and experimental implementation for the ADC are described.
Basic Computer-Aided Learning for a Control Engineering Course
Authors: Chew K. P. , Renfrew A. C. , Young C. P. L. 
Published: January 2017

Basic computer-aided learning for a control engineering course To allow for variation in the rate at which similarly qualified students accept new material, a computer-based aid has been developed to provide self-paced learning as an adjunct to a formal course in Control Systems. The first stage of the courseware is described and student reaction is surveyed.
Sexual Assaults in Singapore: A Comparative Study of Rapists and Molesters
Authors: Lim Leslie 
Published: January 2017

Sexual assaults vary in terms of severity from molestation, which involves touching, stroking, fondling or grabbing of any part of the victim's body, to rape, where victims have been known to suffer severe emotional trauma. The aim of the study is to compare molesters with rapists using hypotheses that molesters and rapists commit their offences at different times of the day, at differing locations and with differing relationships with their victims. The influence of alcohol on both groups was also studied. Convicted molesters and rapists were given a semi-structured interview in prison. Demographic information and details of each offence were obtained from prison records. Comparisons were made of the demography, time, place, reasons for assault, relationship of offender to victims and the role of alcohol and drugs consumed by the perpetrators. Molesters and rapists were of similar age and ethnicity, but differed in that rapists had attained a lower educational level and were more likely to be single. Rapists were more likely to report having drunk alcohol, committing rape after midnight and in secluded places. Molesters struck in the afternoon hours and usually in crowded places. Victims of molesters tended to be relatives whereas victims of rapists were more likely to be ex-spouses or ex-lovers. Molesters tended to give other reasons for their offences. Differences between molesters and rapists could lead to intervention strategies chiefly targeting the issues of poor socialisation skills in molesters and alcohol counselling for rapists.
Personal Use of Hair Dyes and the Risk of Bladder Cancer: Results of a Meta-Analysis
Authors: Huncharek Michael , Kupelnick Bruce 
Published: January 2017

Objective. This study examined the methodology of observational studies that explored an association between personal use of hair dye products and the risk of bladder cancer. Methods. Data were pooled from epidemiological studies using a general variance-based meta-analytic method that employed confidence intervals. The outcome of interest was a summary relative risk (RRs) reflecting the risk of bladder cancer development associated with use of hair dye products vs. non-use. Sensitivity analyses were performed to explain any observed statistical heterogeneity and to explore the influence of specific study characteristics of the summary estimate of effect. Results. Initially combining homogenous data from six case-control and one cohort study yielded a non-significant RR of 1.01 (0.92, 1.11), suggesting no association between hair dye use and bladder cancer development. Sensitivity analyses examining the influence of hair dye type, color, and study design on this suspected association showed that uncontrolled confounding and design limitations contributed to a spurious non-significant summary RR. The sensitivity analyses yielded statistically significant RRs ranging from 1.22 (1.11, 1.51) to 1.50 (1.30, 1.98), indicating that personal use of hair dye products increases bladder cancer risk by 22% to 50% vs. non-use. Conclusion. The available epidemiological data suggest an association between personal use of hair dye products and increased risk of bladder cancer.
Socioeconomic Factors and the Risk of Anencephaly in a Mexican Population: A Case-Control Study
Authors: Muñoz Julia Blanco , Lacasaña Marina , Aburto Victor Hugo Borja , Sánchez Luisa Elvira Torres , García Ana María García , Carrillo Lizbeth López 
Published: January 2017

Objective. The study was designed to evaluate the association between socioeconomic level (as measured by maternal education, maternal occupation, and monthly family income) and anencephaly. Methods. The authors conducted a case-control study using data from the Epidemiological Surveillance System Register for Neural Tube Defects for three states of the Mexican Republic: Puebla, Guerrero and the State of Mexico. Mothers of 151 cases of infants born with anencephaly and mothers of 151 control infants born during the period March 2000 to February 2001 were interviewed about their socioeconomic characteristics and other factors including reproductive history, use of prenatal care, use of tobacco and alcohol, fever during pregnancy, and folic acid supplementation. Results. After adjustment for potential confounders, a risk gradient was seen with decreasing maternal education. Women with less than a primary school education (adjusted odds ratio [OR] = 3.0; 95% confidence interval [CI] 1.2, 7.6) and women who had completed primary school but had not completed junior high school (adjusted OR=2.2; 95% CI 0.9, 5.7) had higher risks of giving birth to an infant with anencephaly, compared to women with a higher educational level. A monthly income ⩽1,000 pesos (approximately $100 U.S.) was also associated with a higher risk of anencephaly (OR=2.5; 95% CI 1.2, 5.1). Women employed in industry or agriculture during the acute risk period (three months prior to conception to one month after conception) had a risk 6.5 times (95% CI 1.4, 29.6) that of professional and business women. Conclusions. This study helps to identify groups that may be especially vulnerable to this type of congenital malformation so that primary and secondary preventive strategies can be targeted to these groups.
Influence of Social Factors on Avoidable Mortality: A Hospital-Based Case-Control Study
Authors: Bautista Daniel , Alfonso José Luis , Corella Dolores , Saiz Carmen 
Published: January 2017

Objective. The effect of socioeconomic factors on avoidable mortality at an individual level is not well known, since most studies showing this association are based on aggregate data. The purpose of this study was to determine socioeconomic differences between those patients who die of avoidable causes and those who do not die. Methods. A matched case-control study was carried out regarding in-hospital avoidable mortality (Holland's medical care indicators) that occurred in a university hospital serving a Spanish-Mediterranean population during a 30-month period. Results. We studied 82 cases of death from avoidable causes and 300 controls matched on medical care indicators and age. The variables that showed a statistically significant association with in-hospital avoidable mortality were number of diagnoses (the greater the number, the higher the risk), length of stay (patients staying seven or more days presented a lower risk), and education. Those patients with low and middle educational levels showed a greater risk of avoidable mortality (adjusted odds ratio=3.57 and 2.82, respectively) than those patients with higher levels of education. Conclusions. Consistent with the findings of studies based on aggregate data, our case-control analyses indicated that among several socioeconomic variables studied, educational level was significantly associated with the risk of in-hospital avoidable mortality, regardless of age and medical care indicators. Patients with low levels of education (<6 years of schooling) were at highest risk for in-hospital avoidable mortality, followed by those with middle levels of education (7–10 years of schooling).