bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic review of crosswalks for converting patient-reported outcome measure scores in hip, knee, and shoulder replacement surgery
Authors: Ackerman Ilana N , Soh Sze-Ee , Hallstrom Brian R , Fang Yi Ying , Franklin Patricia , Lützner Jörg , Ingelsrud Lina Holm 
Published: September 2024

Background and purpose: We aimed to systematically review studies of crosswalks for converting patient-reported outcome measure (PROM) scores used in joint replacement, and develop a database of published crosswalks.Methods: 4 electronic databases were searched from January 2000 to May 2023 to identify studies reporting the development and/or validation of crosswalks to convert PROM scores in patients undergoing elective hip, knee, or shoulder replacement surgery. Data on study and sample characteristics, source and target PROMs, and crosswalk development and validation methods were extracted from eligible studies. Study reporting was evaluated using the Mapping onto Preference-based measures reporting Standards (MAPS) checklist.Results: 17 studies describing 35 crosswalks were eligible for inclusion. Unidirectional crosswalks were available to convert hip-specific (Oxford Hip Score [OHS]) and knee-specific (Oxford Knee Score [OKS]) scores to the EQ-5D-3L/EQ-5D-5L. Similar crosswalks to convert disease-specific scores (WOMAC) to the EQ-5D-3L, EQ-5D-5L, and ICECAP-O Capability Index were identified. Bidirectional crosswalks for converting OHS and OKS to the HOOS-JR/HOOS-12 and KOOS-JR/KOOS-12, for converting WOMAC to the HOOS-JR/KOOS-JR, and for converting HOOS-Function/KOOS-Function to the PROMIS-Physical Function were also available. Additionally, crosswalks to convert generic PROM scores from the UCLA Activity Scale to the Lower Extremity Activity Scale in both directions were available. No crosswalks were identified for converting scores in shoulder replacement. Development methods varied with the type of target score; most studies used regression, item response theory, or equipercentile equating approaches. Reporting quality was variable, particularly for methods and results items, impacting crosswalk application.Conclusion: This is the first synthesis of published crosswalks for converting joint-specific (OHS, OKS, HOOS, KOOS), disease-specific (WOMAC), and generic PROMs scores (PROMIS-Physical Function, UCLA Activity Scale, Lower Extremity Activity Scale) used to assess joint replacement outcomes, providing a resource for data harmonization and pooled analysis. Crosswalks were developed using regression methods (9 studies), equipercentile equating methods (5 studies), a combination of equipercentile equating and item response theory methods (2 studies), and a combination of regression and equipercentile equating methods (1 study). A range of crosswalk validation approaches were adopted, including the use of external datasets, separate samples or subsets, follow-up data from additional time points, or bootstrapped samples. Efforts are needed to standardize crosswalk methodology and achieve consistent reporting.
Urinary stone assessment in a single-phase may replace the unenhanced and multiphase computed tomography protocol in painless visible haematuria
Authors: Galtung Kristina Flor , Lauritzen Peter Mæhre , Sandbæk Gunnar , Bay Dag , Baco Eduard , Rud Erik 
Published: September 2024

Objective: Painless visible haematuria (VH) necessitates a computed tomography (CT) usually consisting of one unenhanced and two to three contrast enhanced acquisitions to detect urinary tract stones and malignancy. Recently, we demonstrated that a single nephrographic phase (NP) CT sufficed in detecting malignancy in patients with painless VH. Now, we aim to evaluate the diagnostic performance of single NP CT in stone detection and size measurements in the same cohort.
Material and methods: “A Prospective Trial for Examining Haematuria using Computed Tomography” (PROTEHCT) was a single-center prospective diagnostic study in patients with painless VH between September 2019 and June 2021. All underwent four-phase CT (reference standard) from which a single NP CT (experimental) was extracted. Two randomised readers independently assessed the experimental CT for urinary stones and size. Statistical analysis included diagnostic accuracies and inter-reader agreement (kappa) of experimental CT, and size correlation (Spearman’s ρ) between experimental CT and reference standard.
Results: In 308 included patients (median age: 68 years, 250 males), urinary stones (median size 5 mm) were diagnosed in 21%. The per-patient experimental CT sensitivity was 86% (97% for stones ≥ 5 mm), specificity was 98% and accuracy was 96%. The experimental CT sensitivity for detecting kidney stones was 78% (89% for stones ≥ 5 mm), and 100% for bladder and ureteral stones. No missed stone required active treatment. The inter-reader agreement was almost perfect (96%, k = 0.85). The correlation in stone size was very strong (ρ = 0.91).
Conclusions: A single NP CT is sufficient in detecting and measuring urinary stones in patients with painless VH.
Pengujian In Vitro Serum Antiacne Kombinasi Ekstrak Daun Kemangi dan Rimpang Kunyit
Authors: Fitri Cahyani Mayassa , Halimatushadyah Ernie , Krismayadi  
Published: September 2024

Abstract—Acne is a chronic inflammation of the pilosebaceous follicles which is characterized by excess oil production caused by the bacterium Propionibacterium acnes. The content of flavonoids in basil leaves and the content of curcumin in turmeric rhizome can be used as an anti-acne treatment. The purpose of this study was to determine the anti-acne activity of a single extract of basil leaves and a single extract of turmeric rhizome, to determine the ability of the combination two extracts to inhibit acne-causing bacteria and to formulate combination of basil leaf extract and turmeric rhizome into a serum preparation to determine antibacterial activity against Propionibacterium acnes. The research method used was experimental by testing the antibacterial activity of Propionibacterium acnes in vitro. Antibacterial activity test results in serum showed a negative control, namely serum base did not have an inhibition zone, positive control clindamycin phosphate showed an inhibition zone of 13.20 mm, with a ratio between extracts of turmeric rhizome and basil leaves 1:4, the diameter of the inhibition zone was obtained at a concentration of 30 % of 5.7 mm, 40% concentration of 7.38 mm and 50% concentration of 8.11 mm. Statistical analysis was carried out using the Shapiro-Wilk, Levene Statistics, and One Way Anova methods (p<0.05).
Keywords: acne, basil, p. acnes, serum, turmeric

Abstrak—Jerawat merupakan peradangan kronik folikel pilosebasea yang ditandai dengan adanya produksi minyak berlebih yang disebabkan oleh bakteri Propionibacterium acnes. Kandungan flavonoid pada daun kemangi dan kandungan kurkumin pada rimpang kunyit dapat dimanfaatkan sebagai pengobatan antijerawat. Sediaan farmasi yang dapat digunakan untuk mengatasi masalah kulit berjerawat yaitu serum. Tujuan penelitian ini adalah mengetahui aktivitas antijerawat pada ekstrak tunggal daun kemangi dan ekstrak tunggal rimpang kunyit, mengetahui kemampuan kombinasi kedua ekstrak dalam menghambat bakteri penyebab jerawat dan memformulasikan kombinasi ekstrak daun kemangi dan rimpang kunyit menjadi sediaan serum untuk mengetahui aktivitas antibakteri terhadap Propionibacterium acnes. Metode penelitian yang digunakan adalah eksperimental dengan melakukan uji aktivitas antibakteri Propionibacterium acnes secara in vitro. Hasil uji aktivitas antibakteri pada serum menunjukkan kontrol negatif yaitu basis serum tidak mempunyai zona hambat, kontrol positif clindamycin phospat menunjukkan zona hambat sebesar 13,20 mm, dengan perbandingan antara ekstrak rimpang kunyit dan daun kemangi 1:4 diperoleh hasil diameter zona hambat pada konsentrasi 30% sebesar 5,7 mm, konsentrasi 40% sebesar 7,38 mm dan konsentrasi 50% sebesar 8,11 mm. Analisa statistik dilakukan dengan metode Shapiro-wilk, Levene statistic, dan One Way Anova (p<0,05).
Kata kunci: jerawat, kemangi, kunyit, p. acnes, serum
Feed additives supplementation: a potential strategy to ameliorate heat stress in sheep
Authors: Binuni Rebez E. , Sejian V. , Silpa M.V. , Kalaignazhal G. , Devaraj C. , Nikhil K.T. , Ninan J. , Tüfekci H. , Fonsêca V. F. C. , Chauhan S. S. , DiGiacomo K. , Dunshea F.R. , Lacetera N. 
Published: September 2024

Abstract
Given a significant climate-flexible and socio-economic role in developing nations, environmental heat stress imposes a major financial impact on sheep production systems globally endangering their production, reproduction, and growth. In this regard, the adverse effects of heat stress on sheep production systems have to be addressed through adoption of effective heat alleviation measures like animal management, nutritional management and genetic interventions of which the nutritional interventions seems to be the most cost effective way to alleviate heat stress. Nutritional manipulation for heat stress alleviation in sheep involves the use of antioxidant supplements (Vitamin B; Vitamin E and Selenium; Selenium; Zinc sulphate and folic acid; Vitamin C, Vitamin E, Selenium and Zinc; Naringin; Opuntia ficus-indica f. inermis; Açai oil and Brown seaweed like Ascophyllum nodosum and Sargassum latifolium). Further, electrolyte supplements (Dietary Electrolyte Balance (DEB); Sodium bicarbonate and potassium bicarbonate; Sodium hydroxide) have a beneficial effect on thermal responses, respiratory activities, gas exchange parameters, rumen fermentation, blood buffering capacity and acid-base balance. The mineral mixture supplements (Mineral blocks; Mineral mixture and antioxidants; Chromium; Zinc) play a crucial role in increasing the efficiency of antioxidant defence system, immunity-related parameters, production, reproduction, feed digestibility and insulin sensitivity. Probiotic supplements (Lactobacillus acidophilus, Saccharomyces cervisiae, Propionibacterium freudenreichii, Lactobacillus casei, Enterococcus faecium, Lactobacillus lactis, Bacillus subtilis, Propionibacterium freudenreichii, Pediococcus cerevisiae, Megaspha eraelsdenii, Bacillus licheniformis, Aspergillus oryzae, Schizochytrium limacinum, Trichoderma reesei and Saccharomyces cerevisiae) improve lactational performance, dietary energy utilization and productivity. The probiotics (live Saccharomyces cerevisiae) and prebiotics (mannan oligosaccharide plus b-glucans) used in heat stress alleviation improve dietary energy utilisation. Furthermore, the vital role of herbal supplements (Rosemary, Cinnamon, Turmeric, Clove, Naringin, Chestnut tannins, Giloy stem powder, Curcumin, Rocket oil (watercress oil), Flaxseed, Cornus, Oregano, Thyme, Chamomile flowers, Moringa oleifera, Betaine) has been highlighted to promote feed intake, antioxidant status, growth performance, feed utilization, reproductive performance and immune response. Effective adoption of nutritional strategies can thus ensure sustainable sheep production in this changing climate scenario.
Patient needs, functional requirements, aesthetic preferences and barriers in app-based therapy for knee osteoarthritis
Authors: Erjavec Karmen , Kotnik Petra 
Published: September 2024

Abstract

Introduction. Knee osteoarthritis (KOA) is an infl ammatory condition aff ecting over 25% of adults. Web/mobile technology off ers potential benefi ts in the treatment of KOA by improving access to care and reducing costs by utilising mobile devices for medical care and patient education.

Aim. The study aims to answer the question of what needs, functional requirements and aesthetic preferences patients with knee osteoarthritis have and what barriers and facilitators there are when using an app-based therapy.

Material and methods. We used a qualitative research design with in-depth interviews with 20 patients.

Results and conclusion. Interviewees emphasized that effective KOA management apps must address diverse patient needs, ensure accessibility, offer customizable features, provide comprehensive information and self-management tools, support pain relief, enable remote monitoring, integrate with support communities, and be cost-efficient. These apps should combine functional requirements, such as a simple user interface, integration with wearable devices, educational content, exercise guidance, pain management tools, remote consultations, community support, and feedback mechanisms, with aesthetic preferences for clear, accessible design, large fonts, high-contrast colours, suitable interactive elements, consistent layout, guiding animations, and accessibility features like text resizing, voice commands, and audio descriptions. In conclusion, this study underscores the necessity for KOA management apps to integrate diverse functional requirements and aesthetic preferences, ensuring accessibility, customization, comprehensive information, and support features to enhance usability, effectiveness, and patient satisfaction.
A Modal Analysis of the Cantonese Particle Gamzai
Authors: Lee Margaret Chui Yi , Hsiao Katherine Pei-Yi , Lin Jonah Tzong-Hong 
Published: September 2024

Abstract
This paper offers a novel analysis to account for the semantics of the adverbial approximator gam3zai6. New data are presented, illustrating that gam3zai6 should be distinguished from its apparent scalar counterparts such as almost in English and chabuduo ‘almost’ in Mandarin Chinese. Building upon Portner’s (1998) analysis of the progressive in English, we propose a modal analysis of gam3zai6 as a prospective operator which creates an intensional context for the expressed event/state under the scope of prospectivity. We incorporate the temporal indication into the semantics of gam3zai6, enabling a unified account for the diverse interpretations of gam3zai6-sentences.
“A drink for the Soul”: the Coffee tree and Coffee as a Symbol of the Arab National Mentality
Authors: Kukhareva E. V. 
Published: September 2024

In the complex geopolitical situation of the beginning of the twenty-first century and with the change of the vector of interests towards the countries of the East, attention to all aspects of the life of the peoples of these states is increasing due to the urgent need to understand their cultures, lifestyle, and the world around them. These peoples are increasingly active in the international arena, their role in various fields is becoming more noticeable, and it is important to interact with them at various levels. To do this, it is necessary to know what this people live by, what their priorities are, what is important or secondary for them. The complexity of intercultural communication lies in the fact that the national character and mentality of representatives of different linguistic cultures is based on the existing realities of a particular people’s life, its moral values and attitudes, through which various ethnic communities identify themselves and fix their place and purpose in this world. Symbols and images reflecting these ideas take either a material or verbal shell and convey an ethnic picture of the world of a particular people, which is completely different from the ideas of other ethnic groups about what surrounds them. To understand a representative of another linguistic consciousness, it may not be enough to master the vocabulary and grammar of a foreign language. Significant elements of the language in their semantic part also contain an extra-linguistic component, so-called “background knowledge”, which can be gleaned from the history, mythology, literature, and folklore of the people with whom we are interacting. This extra-linguistic component, according to the author, is of great importance for understanding national mentality and national character. It helps to identify other driving forces of the actions of different peoples in the process of intercultural communication, along with their political and economic interests. In this article, the author considers one of the symbols of the national mentality of the Arabs – the coffee tree and its derivative – the coffee drink, which plays an important role in creating a national collective portrait of Arab society. She also attempts to show how and why they occupy such an important place in the Arab national consciousness.
Positive Blood Culture Profile Through Systematic Review
Authors: Lemos Mauro Victor Castro , Zafred Ivana Fiquene , Silva Luís Cláudio Nascimento da , Aliança Amanda Silva dos Santos , Firmo Wellyson da Cunha Araújo , Nunes Márcio Anderson Sousa 
Published: September 2024

Objective: This study aimed to gather data on the prevalence of microorganisms in the bloodstream.

Theoretical Framework: In this topic, the fundamental theoretical bases for research on Bloodstream Infections (BSI) are presented. Epidemiological, microbiological and clinical aspects stand out, including incidence, microorganisms involved, antimicrobial resistance and clinical and economic impacts. Furthermore, the importance of systematic reviews in the synthesis and critical evaluation of available evidence is discussed.

Method: This study was carried out based on a systematic bibliographic review, where data from articles published in scientific journals in the Google Scholar, Lilacs and PubMed databases were collected and selected, from 2012 to 2019.

Results and Discussion: In the various articles analyzed in this review, 52 different microorganisms were found. Staphylococcus aureus and Klebsiella pneumoniae are the most prevalent in the group of microorganisms observed in positive blood cultures. Regarding gender, it was found that of the 2,210 samples corresponding to the total number of positive blood cultures in the 21 articles analyzed, 36% were positive for males and 64% for females.

Research Implications: Highlights the importance of surveillance and effective control of Bloodstream Infections, especially considering the prevalence of microorganisms such as Staphylococcus aureus and Klebsiella pneumoniae, influencing health practices, public policies and hospital protocols.

Originality/Value: This study contributes to the literature by gathering data on the prevalence of microorganisms in Bloodstream Infections, providing essential insights to improve prevention and control practices, directly impacting public health and patient safety.
Saúde mental em tempos de inteligência artificial: estamos na vanguarda de uma nova era?
Authors: Leite Lucas Tamamaru Santos 
Published: September 2024

A inteligência artificial (IA) vem representando uma revolução na assistência médica, especificamente ao que se refere à saúde mental, cujo potencial leva em conta algoritmos de diagnóstico, análise de dados de diversas fontes e monitoramento de pacientes em tempo real, no entanto, questões associadas à privacidade, ao preconceito e ao risco desta ferramenta substituir o atendimento humano também são evidentes; de modo que a regulamentação e o envolvimento do médico são fundamentais para a sua implantação equitativa; não obstante potencializar a tomada de decisões clínicas e a eficiência, em contrapartida, pode secundar os dilemas morais, perda de autonomia e questões relacionadas ao escopo da prática, o alcance de um equilíbrio entre os pontos fortes e as limitações implica em utiliza-la como um suplemento clínico validado sob supervisão médica; a sua trajetória deve estar alinhada à otimização do tratamento de saúde mental e a manutenção do cuidado compassivo; mas não se pode negar que a sua integração na psiquiatria e psicoterapia é uma realidade.
Typical Errors in Russian-Language Speech of Preschool Children in The Situation of Russian-Kyrgyz Bilingualism
Authors: Galkina E. V. , Krasnoshchekova S. V. 
Published: September 2024

What mechanisms are involved in the acquisition of the Russian language by bilingual children? This question is widely studied on the speech of bilinguals. Most of the research is based on the data of bilingual children’s speech acquiring Russian as a native language, however not the dominant one. In this study, we consider a situation in which Russian is one of the two official languages of the country and the most relevant (dominant) one for the child. The aim of the paper is to analyze speech features of preschool children permanently residing in Kyrgyzstan (Bishkek), to identify speech errors most typical of Russian-Kyrgyz bilingual children, to classify and compare them with those, characteristic of other groups of Russian learners. The material includes children’s oral picture-based narratives collected using the MAIN instrument. The narratives were audio recorded, then transcribed and analyzed. The main method of analysis was functional analysis of speech and language data. The analysis of the material shows that our informants used the same speech strategies as bilingual children acquiring Russian as a non-dominant language. The types of errors arising from the use of bilingual strategies are: non-distinguishing grammar gender due to the interference of the second language, use of original forms instead of oblique ones as well as a tendency to use “frozen” forms and constructions, both due to the strategy of simplification. Along with this, we have noted numerous innovations that are characteristic of Russian-speaking monolingual children of earlier age, as well as errors usual in children with atypical speech development. The errors were of similar nature, while the Russian input had different quantity and quality. This indicates the desire of both bilingual and monolingual children to simplify linguistic phenomena, which is probably an optimal cognitive strategy in the situation of parallel learning several languages.