bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward Sustainable Livelihoods: Investigating the Drivers of Purchase Behavior for Green Products
Authors: Wei Chiou‐Fong , Chiang Chang‐Tang , Kou Tun‐Chih , Lee Bruce C Y 
Published: January 2017

AbstractGreen consumption involves comprehensive concerns that address the broad scope of sustainability, ecosystem balance, profit‐generation and people. Identifying the factors that influence consumers' purchase behavior enables manufacturers to understand consumers' decision‐making processes and can help them develop more environmentally beneficial products. However, scholars have recently found that a gap exists between environmental concern and consumers' actual purchase behavior. The purpose of this paper is to use cognitive behavior theory to investigate the drivers of green consumption behavior and the missing link in the concern–behavior gap. After collecting 375 valid questionnaires, this study validated the proposed conceptual model using structural equation modeling. The revised model indicates that environmental involvement, informational utility, green advertising skepticism and green trust are antecedent variables of consumer attitudes toward green products. Additionally, this study also provides a possible explanation of and remedies for the concern–behavior gap. Copyright © 2017 John Wiley & Sons, Ltd and ERP Environment
A Synthetic MUC1 Glycopeptide Bearing βGalNAc‐Thr as a Tn Antigen Isomer Induces the Production of Antibodies against Tumor Cells
Authors: Leiria Campo Vanessa , Riul Thalita B. , Oliveira Bortot Leandro , Martins‐Teixeira Maristela B. , Fiori Marchiori Marcelo , Iaccarino Emanuela , Ruvo Menotti , Dias‐Baruffi Marcelo , Carvalho Ivone 
Published: January 2017

AbstractThis study presents the synthesis of the novel protected O‐glycosylated amino acid derivatives 1 and 2, containing βGalNAc‐SerOBn and βGalNAc‐ThrOBn units, respectively, as mimetics of the natural Tn antigen (αGalNAc‐Ser/Thr), along with the solid‐phase assembly of the glycopeptides NHAcSer‐Ala‐Pro‐Asp‐Thr[αGalNAc]‐Arg‐Pro‐Ala‐Pro‐Gly‐BSA (3‐BSA) and NHAcSer‐Ala‐Pro‐Asp‐Thr[βGalNAc]‐Arg‐Pro‐Ala‐Pro‐Gly‐BSA (4‐BSA), bearing αGalNAc‐Thr or βGalNAc‐Thr units, respectively, as mimetics of MUC1 tumor mucin glycoproteins. According to ELISA tests, immunizations of mice with βGalNAc‐glycopeptide 4‐BSA induced higher sera titers (1:320 000) than immunizations with αGalNAc‐glycopeptide 3‐BSA (1:40 000). Likewise, flow cytometry assays showed higher capacity of the obtained anti‐glycopeptide 4‐BSA antibodies to recognize MCF‐7 tumor cells. Cross‐recognition between immunopurified anti‐βGalNAc antibodies and αGalNAc‐glycopeptide and vice versa was also verified. Lastly, molecular dynamics simulations and surface plasmon resonance (SPR) showed that βGalNAc‐glycopeptide 4 can interact with a model antitumor monoclonal antibody (SM3). Taken together, these data highlight the improved immunogenicity of the unnatural glycopeptide 4‐BSA, bearing βGalNAc‐Thr as Tn antigen isomer.
Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates
Authors: Villadsen Klaus , Martos‐Maldonado Manuel C. , Jensen Knud J. , Thygesen Mikkel B. 
Published: January 2017

AbstractGlycobiology is the comprehensive biological investigation of carbohydrates. The study of the role and function of complex carbohydrates often requires the attachment of carbohydrates to surfaces, their tagging with fluorophores, or their conversion into natural or non‐natural glycoconjugates, such as glycopeptides or glycolipids. Glycobiology and its “omics”, glycomics, require easy and robust chemical methods for the construction of these glycoconjugates. This review gives an overview of the rapidly expanding field of chemical reactions that selectively convert unprotected carbohydrates into glycoconjugates through the anomeric position. The discussion is divided in terms of the anomeric bond type of the newly formed glycoconjugates, including O‐, N‐, S‐, and C‐glycosides.
Hit‐Validation Methodologies for Ligands Isolated from DNA‐Encoded Chemical Libraries
Authors: Zimmermann Gunther , Li Yizhou , Rieder Ulrike , Mattarella Martin , Neri Dario , Scheuermann Jörg 
Published: January 2017

AbstractDNA‐encoded chemical libraries (DECLs) are large collections of compounds linked to DNA fragments, serving as amplifiable barcodes, which can be screened on target proteins of interest. In typical DECL selections, preferential binders are identified by high‐throughput DNA sequencing, by comparing their frequency before and after the affinity capture step. Hits identified in this procedure need to be confirmed, by resynthesis and by performing affinity measurements. In this article we present new methods based on hybridization of oligonucleotide conjugates with fluorescently labeled complementary oligonucleotides; these facilitate the determination of affinity constants and kinetic dissociation constants. The experimental procedures were demonstrated with acetazolamide, a binder to carbonic anhydrase IX with a dissociation constant in the nanomolar range. The detection of binding events was compatible not only with fluorescence polarization methodologies, but also with Alphascreen technology and with microscale thermophoresis.
Self‐Assembly of Tunable Heterometallic Ln–Ru Coordination Polymers with Near‐Infrared Luminescence and Magnetocaloric Effect
Authors: Wang Lei , Xie Zhigang , Dang Song , Sun Zhong‐Ming 
Published: January 2017

AbstractA series of heterometallic lanthanide (Ln)–Ru coordination polymers, denoted Gd‐1, Yb‐2, and Nd‐3, were prepared by solvothermal reaction of a carboxylate derivative of [Ru(bpy)3]2+ (Rubpy, bpy=2,2′‐bipyridine), oxalic acid, and Ln(OAc)3 by using the metalloligand strategy. Single‐crystal X‐ray diffraction indicated that the resulting isostructural heterometallic complexes have 1D butterfly‐shaped Ln–Ru‐based coordination chains but show slight differences in the coordination environments of the Ln centers. The introduced Ru(bpy) metalloligands could act as good light‐harvesting antennas to effectively sensitize near‐infrared (NIR) luminescence by energy transfer from the triplet metal‐to ligand charge transfer state of Rubpy units to Ln (Yb or Nd) under the excitation in the visible‐light region. Additionally, dopant‐concentration‐dependent behavior of the Ru‐based emission and sensitized NIR emission was demonstrated in Gd‐1. Finally, the magnetocaloric effect of Gd‐1 was studied. The preparation of such heterometallic coordination polymers offers a versatile platform to investigate dimensionally controlled properties.
Pd‐PEPPSI‐IPentCl: A Useful Catalyst for the Coupling of 2‐Aminopyridine Derivatives
Authors: Khadra Abir , Mayer Stanislas , Organ Michael G. 
Published: January 2017

AbstractThe Pd‐PEPPSI‐IPentCl precatalyst (PEPPSI=pyridine‐enhanced precatalyst preparation stabilisation initiation) has been demonstrated to be highly effective in the coupling of hetero(aryl)chlorides to free 2‐aminopyridine substrates to produce N‐(hetero)aryl‐2‐aminopyridine derivatives. The catalyst has proven to be competent in a number of other difficult cross‐coupling reactions owing to the combination of the 3‐pentyl‐substituted N‐aryl groups and the chlorines on the backbone of the N‐heterocyclic carbene (NHC) core. This same reactivity here allows couplings to take place under very mild conditions (e.g., NaBHT (BHT=2,6‐di‐tert‐butyl‐4‐methylphenol) or carbonate base) such that sensitive functional groups including esters, ketones and nitriles are tolerated. Key is that the same bulk that drives the cross‐coupling also mitigates poisoning of the Pd centre with the 2‐aminopyridine functionality in the starting materials and/or products, which forces the catalyst into inactive, stable resting states.
Donor–Acceptor Control in Grown‐in‐Glass Gallium Oxide Nanocrystals by Crystallization‐driven Heterovalent Doping
Authors: Paleari Alberto , Golubev Nikita V. , Ignat'eva Elena S. , Sigaev Vladimir N. , Monguzzi Angelo , Lorenzi Roberto 
Published: January 2017

AbstractIncorporation of doping ions in nanocrystals is a strategy for providing nanophases with functions directly related to ion features. At the nanoscale, however, doping can also activate more complex effects mediated by perturbation of the nanophase size and structure. Here, we report a paradigmatic case in which we modify grown‐in‐glass γ‐Ga2O3 nanophases by nickel or titanium doping of the starting glass, so as to control the concentration of oxygen and gallium vacancies responsible for the light emission. Optical absorption and luminescence show that Ni2+ and Ti4+ ions enter into the nanophase, but differential scanning calorimetry and X‐ray diffraction indicate that Ni and Ti also work as modifiers of nanocrystal growth. As a result, doping influences nanocrystal size and concentration, which in turn dictate the number of donors and acceptors per nanocrystal. Finally, the chain of effects turns out to control both the intensity and spectral distribution of the light emission.
Change in self‐esteem predicts depressive symptoms at follow‐up after intensive multimodal psychotherapy for major depression
Authors: Dinger Ulrike , Ehrenthal Johannes C. , Nikendei Christoph , Schauenburg Henning 
Published: January 2017

AbstractReduced self‐esteem is a core symptom of depression, but few studies have investigated within‐treatment change of self‐esteem as a predictor of long‐term outcome in depression. This study investigated change in self‐esteem during 8 weeks of multimodal, psychodynamically oriented psychotherapy for 40 depressed patients and tested whether it would predict outcome 6 months after termination. Data was drawn from a randomized clinical pilot trial on day‐clinic versus inpatient psychotherapy for depression. Findings supported the association between change in self‐esteem and follow‐up depression severity, even when controlling for within‐treatment symptom change. Change in self‐esteem was not related to overall symptoms and interpersonal problems at follow‐up. Thus, change in self‐esteem may be an important variable in preventing relapse for depression.Key Practitioner Message

Self‐esteem is related to depressive symptoms and interpersonal problems.
Improvement of self‐esteem during psychotherapy correlates with improvements of symptoms and interpersonal problems.
Change of self‐esteem during psychotherapy predicts depressive symptoms 6 months after termination of therapy.
When treating depressed patients, psychotherapists should work towards an improvement of self‐esteem in order to prevent relapse.
Calcified Myoma of Utero‐Ovarian Ligament in a Pubertal Girl
Authors: Wallach Robert C. 
Published: January 2017

Wallach, R. C. (Dept. of Obstetrics and Gynecology, Beth Israel Medical Center, Mount Sinai School of Medicine, New York, N.Y., USA) Calcified myoma of utero‐ovarian ligament in a pubertal girl.Int J Gynaecol Obstet 14: 567–569, 1976.A calcified myoma of the utero‐ovarian ligament was encountered in a 13‐year‐old girl. The age of the patient and the unusual location prompt this report of a possibly unique entity, and the pertinent literature is cited.
Electromyogram of Pelvic Floor Muscles in Genital Prolapse
Authors: Sharf Benjamin , Zilberman Adolf , Sharf Mordechai , Mitrani Avraham 
Published: January 2017

ABSTRACTIn order to elucidate the pathophysiological mechanisms of genital prolapse, an electromyographic (E.M.G.) survey of the perineal muscles is presented. Fifty women with genital prolapses and stress incontinence, plus 10 women as a control group, were examined. The results pointed to a primary neurogenic lesion in 50% of cases with a denervation pattern in extreme cases. Our hypothesis is that the muscular deficiency in genital prolapse is secondary to a neurogenic lesion. Operations were performed on 31 women, subsequently re‐examined electromyographically. In those cases with severe denervation, the surgical results were poor and relapse occurred. It is suggested that the E.M.G. can be a preoperative prognostic test, as well as a tool in evaluation of conservative treatment in genital prolapse.
Bleeding in Gynecological Surgery: Influence of Low Dose Heparin
Authors: Gjønnæss Halvard , Abildgaard Ulrich 
Published: January 2017

ABSTRACTNinety‐five patients above 50 years who underwent surgical treatment in the Gynecological Department, Aker Hospital, were treated either with low dose heparin or with placebo for 7 days. Two of the heparintreated patients and 2 of the controls received blood transfusions postoperatively. Excluding these 4 patients, the mean fall in hemoglobin concentration was identical in the two groups. The fall in hemoglobin concentration was more pronounced in patients with body weights below 70 kg. Local hematomas were seen more frequently in the heparin series. Clinical signs of thrombophlebitis developed in 2 patients 9 and 12 days postoperatively. One of these patients, who belonged to the heparin series, died from pulmonary embolism.
Permanent Sterilization through a Posterior Colpotomy
Authors: Brenner W. E. , Edelman D. A. 
Published: January 2017

ABSTRACTTo assist gynecologists in their evaluation of sterilization procedures, sterilization of the not recently pregnant patient through a posterior colpotomy is discussed. Patient selection, preoperative and postoperative procedures, surgical technique and difficulties, effectiveness and complications are detailed. Surgical difficulties and early postoperative complications are evaluated from data reported to the International Fertility Research Program on 398 patients sterilized by classical methods through a posterior colpotomy. It appears that skilled vaginal surgeons can perform sterilization through a colpotomy with clinically acceptable rates of surgical difficulties and complications. Some investigational techniques of tubal occlusion performed through a colpotomy may result in lower rates of morbidity.
Postpartum and Postabortion Sterilization
Authors: Purandare B. N. 
Published: January 2017

ABSTRACTTo evaluate the feasibility of postpartum and postabortion sterilization, several studies (including unpublished data) from the India Fertility Research Programme and the International Fertility Research Program were reviewed. Within 36 hours of a term delivery, sterilization by either laparoscopy or laparotomy is associated with clinically acceptable rates of technical difficulties, complications, failures, and duration of hospitalization. Following first trimester abortions, it appears satisfactory to perform sterilization via laparotomy, laparoscopy, colpotomy, or culdoscopy. Following second trimester abortions, sterilization by laparoscopy or laparotomy is satisfactory. Because laparoscopy and culdoscopy require special training and equipment, they are of limited usefulness compared to laparotomy and colpotomy.
Outpatient Culdoscopic Sterilization: an Evaluation
Authors: Holtrop Hugh R. , Goldsmith Alfredo , Edelman David A. , Jr Cedric W. Porter , Sandalls Katherine 
Published: January 2017

ABSTRACTThis study was conducted to evaluate the surgical and early postoperative complications of culdoscopic sterilization. Data were analyzed from three hospitals —one each in Jamaica (180 cases), Lebanon (195 cases), and Singapore (150 cases). In all three, culdocopy had been recently introduced as an outpatient sterilization procedure. Seven (1.3%) of the sterilization procedures could not be completed as a result of complications or failure to visualize both tubes. Technical difficulties occurred in 16.6% of the culdoscopic sterilizations, but most were minor and did not require a change in the planned technique of sterilization. Complications at the time of surgery were infrequent, occurring in only 2.1% of the patients. Early postoperative complications and complaints were reported for 20.2% of the patients but most were inconsequential and did not require treatment. Only 5% of the patients were hospitalized postoperatively. Within one week of the sterilization 90.1 % of the patients had resumed their normal activities. The results of the study demonstrate that there is a place for culdoscopy in outpatient sterilization programs.
Squamous Cell Carcinoma of the Cervix, with Extension in an in situ Fashion into the Endometrium
Authors: Kamalian Nasser , Ghafoorzadeh Djavad 
Published: January 2017

ABSTRACTA 55‐year‐old, white, multiparous woman had an invasive, endocervical, squamous cell carcinoma. The tumor had spread superficially into the entire endometrial cavity. The lesion abruptly terminated at the squamocolumnar junction, and the exocervix was free of invasion. Apparently, the cervical, malignant, squamous epithelium had spread upward in a superficial fashion and had mechanically replaced the columnar epithelium.
Unification of a Septate Uterus: Mahgoub's Operation
Authors: Mahgoub S. El 
Published: January 2017

ABSTRACTA simple surgical technique for unification of a septate uterus is described. The septum and a small strip of fundus are removed with scissors inserted through two small fundal stabs, and the opening is closed with one mattress suture, which forms an anteroposterior suture line no more than 1 cm long. At the end of the operation, an intrauterine contraceptive device is inserted to prevent uterine adhesions. The operation has several advantages: (a) it leaves a capacious uterine cavity of normal appearance, (b) it avoids large uterine incisions, and thus the possibility of postoperative adhesions or weak uterine scars, and (c) it avoids possible injury to the cornual ends of the Fallopian tubes. This article reports favorable results in 17 women treated with this surgical technique
Preoperative Cervical Dilatation with 15(S)15‐Methyl PGF2α Methyl Ester Pessaries
Authors: Chatterjee Tapan K. , Grech Edwin S. , Niles Lalitha 
Published: January 2017

ABSTRACTA clinical trial comparing two vaginal dose schedules of 15(S)15‐methyl prostaglandin F2α (PGF2α) methyl ester (4 or 6 mg) for preoperative dilatation of the cervix is described. The trial included 28 patients at 8–12 weeks' gestation. Vaginal pessaries containing either 1.0 mg (15 patients) or 1.5 mg (13 patients) of the prostaglandin analogue were administered every 3 hours (maximum, 4 doses). The success rates for the two groups were 93% and 100%, respectively. Sixty percent of the patients aborted before the planned vacuum aspiration. Minor side effects, primarily vomiting and diarrhea, occurred in approximately 80% of the cases and were more prominent with the higher dose pessary. It is concluded that the vaginal administration of 15(S)15‐methyl PGF2α methyl ester is highly effective for preoperative dilatation of the cervix before suction curettage abortion.
Laparoscopic Electrocoagulation and Tubal Ring Techniques for Sterilization: A Comparative Study
Authors: Koetsawang Suporn , Srisupandit Suwanee , Cole Lynda Painter 
Published: January 2017

ABSTRACTFrom August 1975 through May 1976, a comparative study was made of the effects of sterilization by standard electrocoagulation and tubal ring application techniques. The two techniques were randomly assigned to 300 patients. Results show that standard electrocoagulation and tubal ring procedures can easily and safely be performed on an outpatient basis, using local anesthetics and analgesics. Rates of surgical complications for both techniques were clinically acceptable, although tubal ring patients had a higher rate. Pain during the procedure and during the immediate recovery period was more severe for tubal ring patients. Despite the higher incidence of surgical complications and pain associated with the ring, many physicians prefer this method of sterilization because it eliminates the possibility, inherent in electrocoagulation, of inadvertent serious electrical burns.
Collagenolytic Activity and Steroid Levels After Administration of Dehydroepiandrosterone Sulfate
Authors: Mochizuki Matsuto , Honda Tomohiko , Tojo Shimpei 
Published: January 2017

ABSTRACTSeventy‐five pregnant women in their 38th to 41st weeks of gestation were given a single intravenous injection of 200 mg of dehydroepiandrosterone sulfate (DHAS). The changes in estriol, 17β‐estradiol and progesterone levels in the serum, the uterine cervix and the myometrium of the placenta‐implanting site were then determined. Estriol levels remained unchanged both in serum and tissue, but the level of 17β‐estradiol increased sharply both in serum and tissue after four hours. The increases of 17β‐estradiol in the serum and the portio vaginalis of the same patient were well correlated (r = 0.79898), but the percentage of increase was much higher in the portio vaginalis than in the serum (p < 0.001). Serum progesterone levels did not change initially, but always decreased within four or eight hours in cases in which labor had started or delivery was accomplished within 24 hours (p < 0.01 at four hours). The total amount of collagenase was determined in ten subjects before and after the administration of DHAS. The total collagenase activity was elevated by an average of 152.3%. The peak of activity was accelerated from the fourth to the second day (p < 0.001) of the culture. A probable mechanism of DHAS action in accelerating cervical ripening is presented.
Implementation of a Successful Outpatient Laparoscopic Sterilization Program in Calcutta
Authors: Lilaram Duru , Basu Subhasree 
Published: January 2017

ABSTRACTThis study presents data on 109 women undergoing laparoscopic sterilization by tubal rings at the Calcutta Medical Research Institute and Hospital. The average operating time was 15 minutes and the average stay in the recovery room was 4 hours. The ovarall complication rate was 18%, including surgical and early postoperative complications. All patients returned for follow‐up. Long‐term follow‐up will be required to determine the rates of delayed complications and the efficacy of the procedure.
Tubal Occlusion via Laparoscopy in Latin America: An Evaluation of 8186 Cases
Authors: Cole Lynda Painter , Colven Christine E. , Goldsmith Alfredo 
Published: January 2017

ABSTRACTEase of performance, safety and effectiveness of laparoscopic sterilization techniques are evaluated for 8186 procedures (6995 interval, 680 postabortion and 511 postpartum) performed in Latin America from June 1972 through February 1978. The tubes were occluded via electrocoagulation or application of the spring‐loaded clip or the tubal ring. Less than 1% of the procedures were declared technical failures (ie, those which were not completed as planned). For all the tubal occlusion techniques, interval patients had the lowest rate of surgical complications. Pregnancy rates were low for the electrocoagulation and for the tubal ring techniques; patients sterilized by the spring‐loaded clip, however, had a significantly higher pregnancy rate.
Continuation of Abdominal Pregnancy Complicated by Preeclampsia Three Weeks After Birth of an Intrauterine Twin
Authors: Ekwempu C. C. 
Published: January 2017

ABSTRACTA case of heterotopic pregnancy in a 22‐year‐old multigravida is presented. The extrauterine baby was delivered alive three weeks after the intrauterine pregnancy had ended at term in spite of an associated preeclampsia. The inhibition of lactation resulting from the continuation of the extrauterine pregnancy resulted in marasmus for the first baby. The implications and especially the etiology of preeclampsia occurring in extrauterine pregnancy are discussed.