bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preoperative perineural invasion in rectal cancer based on deep learning radiomics stacking nomogram: A retrospective study
Authors: Zhao Zhi-Chun , Liu Jia-Xuan , Sun Ling-Ling 
Published: September 2024

BACKGROUND
The presence of perineural invasion (PNI) in patients with rectal cancer (RC) is associated with significantly poorer outcomes. However, traditional diagnostic modalities have many limitations.
AIM
To develop a deep learning radiomics stacking nomogram model to predict preoperative PNI status in patients with RC.
METHODS
We recruited 303 RC patients and separated them into the training (n = 242) and test (n = 61) datasets on an 8: 2 scale. A substantial number of deep learning and hand-crafted radiomics features of primary tumors were extracted from the arterial and venous phases of computed tomography (CT) images. Four machine learning models were used to predict PNI status in RC patients: support vector machine, k-nearest neighbor, logistic regression, and multilayer perceptron. The stacking nomogram was created by combining optimal machine learning models for the arterial and venous phases with predicting clinical variables.
RESULTS
With an area under the curve (AUC) of 0.964 [95% confidence interval (CI): 0.944-0.983] in the training dataset and an AUC of 0.955 (95%CI: 0.900-0.999) in the test dataset, the stacking nomogram demonstrated strong performance in predicting PNI status. In the training dataset, the AUC of the stacking nomogram was greater than that of the arterial support vector machine (ASVM), venous SVM, and CT-T stage models (P < 0.05). Although the AUC of the stacking nomogram was greater than that of the ASVM in the test dataset, the difference was not particularly noticeable (P = 0.05137).
CONCLUSION
The developed deep learning radiomics stacking nomogram was effective in predicting preoperative PNI status in RC patients.
Specific features of the development of the construction industry in the conditions of sanctions
Authors: Sharyapova E. A. , Zhelnina E. S. , Andreeva A. A. 
Published: September 2024

The article argues that construction has always been a necessary and the largest sector of the national economy in the Russian Federation (RF). Construction, which is a long production cycle, is characterized by the active movement of material, technical and human resources, which always indicates the relevance of considering the problems of this industry. In the article the author analyzes the development of the construction industry in modern conditions in Russia, and also puts forward theses about the causes of possible and probable risks and threats to the evolution of the construction industry under international sanctions against the Russian Federation.
Responsibility of information intermediaries: Comparative analysis of activity in Russia and abroad
Authors: Tarasevich A. M. , Khodot K. Yu. , Kolmogorov M. V. 
Published: September 2024

The present article is devoted to the consideration of civil liability of information intermediaries as subjects of civil legal relations and their activities in Russia and abroad. It is argued that in the modern world information has become one of the key resources influencing all spheres of society. The role of information intermediaries, which provide access to information, is becoming more and more significant. In modern society, with their direct participation the creation of information space, as well as influence on the formation of public opinion takes place. The authors conducted a comparative analysis of the activities of information intermediaries in Russia and abroad, taking into account their role in ensuring information security and protecting freedom of speech. The study reveals similarities and differences in the work of information intermediaries in different countries and assesses their impact on public development. The specific features of the work of information intermediaries in these or those states are shown, responsibility mechanisms for ensuring effective protection of information security and development of free information space are proposed. Based on a comparative analysis of the activities of information intermediaries in Russia and abroad, the authors conclude that it is necessary for the state to take a more active part in regulating and controlling the activities of information intermediaries. Their responsibility should be based on the principles of fairness, proportionality and protection of users’ rights, rather than on censorship and restrictions on freedom of speech.
Efektifitas Website Desa Sebagai Media E-Government Dalam Pelayanan Publik Di Desa Margahayu Tengah Menggunakan Pendekatan Rasch Model
Authors: Nur Rahmadianie Fathya 
Published: September 2024

Technological advances have brought us into the era of "e-services". Scholars and academics are trying to understand the impact of e-services on people's lives, satisfaction, and future service quality. With the advent of e-government, this understanding has led us to a better framework for delivering e-services. In 2017, Diskominfo and DPMD of Bandung Regency Government have implemented the installation of OpenSID-based village websites. This study aims to determine the level of effectiveness of the village website as an e-government media in public services in Margahayu Tengah Village. This research was analyzed using the Rasch Model. This research was conducted by distributing questionnaires in the form of google form links to the community with several questions related to the village website that the community can access. This study uses Rasch modes in interpreting the results of quantitative research. The sample of this study consisted of 53 respondents and the results showed that respondents still quite understand how to access the village website and the level of effectiveness of the village website as an e-government media in public services is quite good.

ABSTRAK

Kemajuan teknologi telah membawa kita ke era "layanan elektronik". Ahli ilmu dan akademisi sedang berusaha memahami dampak layanan elektronik terhadap kehidupan, kepuasan, dan kualitas layanan di masa mendatang. Dengan munculnya pemerintahan elektronik (e-government), pemahaman ini telah mengarahkan kita ke kerangka kerja yang lebih baik dalam memberikan layanan elektronik. Pada tahun 2017, Diskominfo dan DPMD Pemerintah Kabupaten Bandung telah mengimplementasikan pemasangan website desa berbasis OpenSID. Penelitian ini bertujuan untuk mengetahui tingkat efektifitas website desa sebagai media e-government dalam pelayanan publik di Desa Margahayu Tengah. Penelitian ini dianalisis menggunakan Model Rasch. Penelitian ini dilakukan dengan membagikan kuesioner berupa link google formulir kepada masyarakat dengan beberapa pertanyaan yang berkaitan dengan website desa yang masyarakat dapat di akses oleh masyarakat. Penelitian ini menggunakan rasch modes dalam menginterpretasikan hasil penelitian kuantitatif. Sampel dari penelitian ini terdiri dari 53 responden dan hasil penelitian menunjukan bahwa responden masih cukup memahami cara mengakses website desa dan tingkat efektifitas website desa sebagai media e-government dalam pelayanan publik cukup baik.
ENSINO SUPERIOR E PRÁTICAS INCLUSIVAS
Authors: Araújo Alves Josemery , Venâncio Martins Maria Helena , Marçal da Piedade Ana Catarina 
Published: September 2024

The research aims to analyze the perception of students with Specific Needs at the University of Algarve/Portugal regarding inclusion. Specifically, it analyzes inclusive practices, accessibility, the main barriers, and challenges faced by students in their academic lives. The sample (N= 32) is composed of a group of students assisted by the Support Office for Students with Special Educational Needs (GAENEE), aged between 19 and 40 years (M= 24.09; SD= 6.60). The participants answered a survey designed for the study available online. From the analysis and data interpretation, based on thematic analysis, it was found that the measures applied by UAlg generally responded to the e student's needs, although some expressed a certain dissatisfaction. The students feel included and respected, which suggests that UAlg and GAENEE have been developing inclusive practices for non-discrimination and effective participation of these students in university life. Although teaching staff revealed willingness to adapt pedagogical practices to the student's specific needs, the results suggest the need for improved professional qualifications for teachers, and greater knowledge of inclusive methodologies and practices. The present study highlights that there is still some way to go towards an Inclusive University, allowing the results to be used to improve the institutional response, plan actions, and set new targets for action, contributing to the improvement of the inclusion policy and academic support for these students in the university environment.
Impact of baseline body mass index on the long-term prognosis of advanced hepatocellular carcinoma treated with immunotherapy
Authors: Wang Yu-Qin , Pan Di , Yao Zhi-Yuan , Li Yu-Qi , Qu Peng-Fei , Wang Run-Bang , Gu Qing-Hao , Jiang Jie , Han Zheng-Xiang , Liu Hao-Nan 
Published: September 2024

BACKGROUND
Primary liver cancer is the sixth most common cancer worldwide, with hepatocellular carcinoma (HCC) being the most prevalent form. Despite the current availability of multiple immune or immune combination treatment options, the prognosis is still poor, so how to identify a more suitable population is extremely important.
AIM
To evaluate the clinical effectiveness of combining lenvatinib with camrelizumab for patients with hepatitis B virus (HBV)-related HCC in Barcelona Clinic Liver Cancer (BCLC) stages B/C, considering various body mass index (BMI) in different categories.
METHODS
Retrospective data were collected from 126 HCC patients treated with lenvatinib plus camrelizumab. Patients were divided into two groups based on BMI: The non-overweight group (BMI < 25 kg/m2, n = 51) and the overweight/obese group (BMI ≥ 25 kg/m2, n = 75). Short-term prognosis was evaluated using mRECIST criteria, with subgroup analyses for non-overweight (BMI: 18.5-24.9 kg/m2), overweight (BMI: 25-30 kg/m2), and obese (BMI ≥ 30 kg/m2) patients. A Cox proportional hazards regression analysis identified independent prognostic factors for overall survival (OS), leading to the development of a column-line graph model.
RESULTS
Median progression-free survival was significantly longer in the obese/overweight group compared to the non-overweight group. Similarly, the median OS was significantly prolonged in the obese/overweight group than in the non-overweight group. The objective remission rate and disease control rate for the two groups of patients were, respectively, objective remission rate (5.88% vs 28.00%) and disease control rate (39.22% vs 62.67%). Fatigue was more prevalent in the obese/overweight group, while other adverse effects showed no statistically significant differences (P > 0.05). Subgroup analysis based on BMI showed that obese and overweight patients had better progression-free survival and OS than non-overweight patients, with obese patients showing the best outcomes. Multifactorial regression analysis identified BCLC grade, alpha-fetoprotein level, portal vein tumor thrombosis, and BMI as independent prognostic factors for OS. The column-line graph model highlighted the importance of BMI as a major predictor of patient prognosis, followed by alpha-fetoprotein level, BCLC classification, and portal vein tumor thrombosis.
CONCLUSION
BMI is a long-term predictor of the efficacy of lenvatinib plus camrelizumab, and obese/overweight patients have a better prognosis.
A High-Resolution Geochemical and Petrological Investigation of Bifurcating Chromitite Layers of the UG1 Footwall at Impala Platinum Mine, Rustenburg
Authors: Roelofse Frederick , Magson Justine , Nicholson Mariska , Nyakane Tshepo 
Published: September 2024

Abstract
One of the most enigmatic features of the world’s largest layered intrusion, the Paleoproterozoic Rustenburg Layered Suite of the Bushveld Complex, is the bifurcation of chromitite layers associated with the UG1 chromitite. Despite nearly a century of research, no consensus exists regarding the process(es) responsible for the formation of these bifurcated chromitites. Here we report the results of a high-resolution geochemical and petrological investigation conducted on an ∼195 m2 exposure of anorthositic footwall of the UG1 exposed by mining activities at No. 11 Shaft, Impala Platinum Mine, Rustenburg. Samples were taken from four sample cuts across the footwall exhibiting complex chromitite bifurcations in order to study lateral and vertical variations in the mineral chemistry of plagioclase and chromite and the Sr-isotopic composition of plagioclase as determined by LA-MC-ICP-MS. Our investigation supports the idea that several processes were responsible for the formation of the macroscopic features observed in the studied exposure. A sequence of numerous alternating layers of thin chromitite and anorthosite occurring between a thick basal and upper chromitite layer likely formed during a period of intense seismicity related to the emplacement of the Bushveld Complex. Chromite within these chromitite layers is thought to have nucleated and grown in situ on the chamber floor from a basal magma layer with a composition close to the chromite–plagioclase cotectic. This happened in response to the introduction of evolved, H2O-rich interstitial melts from the compacting crystal mush into the basal magma layer, a process aided by repeated shock waves passing through the chamber. Evidence for the involvement of H2O-enriched melts in the genesis of these thin chromitite layers is preserved in plagioclase that is anomalously calcic and poor in K2O compared to the plagioclase found in the intervening anorthosite layers and the relative abundance of phlogopite within chromitite layers. Additional bifurcations formed in response to the injection of chromite-rich slurries from the thick upper chromitite layer into the sequence below.
French energy imperialism in Vietnam and the conquest of Tonkin (1873-1885)
Authors: Campagne Armel 
Published: September 2024

Cet article montre que la conquête française du Vietnam a été entreprise notamment dans l'optique de l’appropriation de ses ressources en charbon, et que l’impérialisme française était dans ce cas un « impérialisme énergétique ». Il défend ainsi l’idée qu’on peut analyser la conquête française du Tonkin et de l’Annam (1873-1885) comme étant notamment le résultat d’une combinaison des impérialismes énergétiques de la Marine, de l’administration coloniale cochinchinoise, des politiciens favorables à la colonisation et des hommes d’affaires. Au travers des archives militaires, diplomatiques et administratives et d’une réinterprétation de l’historiographie existante, il explore la dynamique de l’impérialisme énergétique français au Vietnam durant la phase de conquête.
Creating Supply, Creating Demand: Gas and Electricity in Montréal from the First World War to the Great Depression
Authors: Hatton-Proulx Clarence 
Published: September 2024

Réduire l’utilisation d’énergie est un impératif urgent pour les sociétés occidentales. Pourtant, il est dur d’anticiper comment cela se fera et quelles conséquences seront engendrées. Cet article avance que l’étude de l’histoire énergétique aide à comprendre la flexibilité des systèmes énergétiques. À partir du cas de Montréal, il analyse la fluctuation de l’offre et de la demande en électricité et en gaz entre la Première Guerre mondiale et la Grande dépression, une période marquée autant par l’expansion que par la stagnation des systèmes énergétiques. En étudiant les activités de la compagnie énergétique monopolistique de la ville ainsi que les pratiques des consommatrices et consommateurs d’énergie, cet article propose une typologie de quatre différents types de flexibilité énergétique : flexibilité à la hausse menée par les fournisseurs, flexibilité à la baisse menée par les fournisseurs, flexibilité à la hausse menée par les consommateurs, flexibilité à la baisse menée par les consommateurs. Les conclusions de cette analyse ont des répercussions importantes sur l’analyse des mégaprojets énergétiques futurs et sur le façonnement de la consommation d’énergie. Elles montrent aussi comment l’histoire énergétique révèle la manière dont les structures héritées du passé influencent les décisions futures.
Les dépenses de la Sécurité sociale à l’épreuve de la Covid-19
Authors: Dort Aurélie 
Published: September 2024

La crise sanitaire représente un coût certain pour l’État et la Sécurité sociale, mais elle traduit aussi un interventionnisme étatique important à travers le Ségur de la santé et la mise en place d’une réforme longtemps attendue : la création d’une nouvelle branche de la Sécurité sociale.
Certification de crise et crise de la certification : les comptes de la Sécurité sociale et la Covid-19
Authors: Kott Sébastien 
Published: September 2024

Les comptes des organismes de sécurité sociale traduisent l’activité d’un secteur très particulier tant par ses missions que par son organisation. Le déploiement d’une comptabilité en droits constatés ne s’y est pas fait sans difficultés comme en témoigne le caractère chaotique des premiers actes de certification du régime général. On pouvait penser que la situation s’était améliorée et que la qualité comptable était assurée. Mais les comptes du régime général se sont de nouveau heurtés à l’écueil de leur certification lors de la crise sanitaire. Cette certification de crise traduit alors une forme de crise de la certification des comptes publics en ce qu’elle met en lumière autant la spécificité de l’information financière des entités non marchandes que le statut particulier de l’organe chargé de cette certification : une institution supérieure de contrôle qui maintient sa ligne en dépit des circonstances… mêmes exceptionnelles.
L’OMC et le FMI en soutien aux pays pauvres contre la Covid-19 : leçons pour l’avenir
Authors: Pellet Rémi 
Published: September 2024

Pour aider les pays pauvres contre les conséquences économiques et financières de la pandémie mondiale de Covid-19, l’Organisation mondiale du commerce (OMC) leur a permis de « lever », sous certaines conditions, les brevets sur les vaccins contre la Covid-19. D’autre part, le Fonds monétaire international (FMI) a augmenté les droits de tirage spéciaux (DTS) pour que les États pauvres puissent s’endetter à des taux faibles et sans conditionnalité. Malheureusement ces deux décisions n’ont pas eu les effets escomptés et elles étaient critiquables dans leur principe même.
Beliefs affecting ART adherence in newly diagnosed HIV-positive participants in Manzini, Eswatini
Authors: Mango Thabiso , Kasese-Hara Mambwe , Mulaudzi Mamakiri 
Published: September 2024

Background: Achieving optimal adherence to antiretroviral therapy (ART) is challenging. Consistency in HIV care and treatment is crucial for achieving viral load suppression and preventing HIV-related illnesses, disease progression to AIDS, mortality, drug resistance, and onward transmission.Objectives: The purpose of this research was to gain a comprehensive understanding of the beliefs that play a role in determining the level of ART adherence among individuals newly diagnosed with HIV. By examining these beliefs, the researchers aimed to identify potential barriers and facilitators to adherence, ultimately contributing to the development of effective interventions and strategies to improve ART adherence.Method: An exploratory qualitative approach was employed in this study, utilising the Theory of Planned Behaviour (TPB) as its theoretical framework. To gather insights, in-depth interviews were conducted with 19 participants recruited post diagnosis, who shared their beliefs regarding ART adherence. Thematic analysis identified beliefs, categorised under TPB precursors, namely behavioural outcomes, subjective norms, and perceived behavioural control.Results: Participants emphasised health improvement, treatment effectiveness, and disease prevention as advantages to ART adherence, while disadvantages included fear of lifelong commitment, side effects, and stigma. ART adherence was enhanced by family support but impeded by a number of social factors. Participants expressed confidence in creating personal reminders or seeking external help, but anticipated various challenges.Conclusion: The research has shown that the beliefs affecting ART adherence in individuals recently diagnosed with HIV but not yet on treatment are like those that have been reported to influence adherence in HIV-positive participants currently receiving treatment.
Improved Culture Positivity Rate after Modified Culture Technique of Dialysis Effluent Fluid in Peritoneal Dialysis-related Peritonitis Cases
Authors: Gupta Shilpi , Hazra Nandita 
Published: September 2024

Abstract

Background and Aims:
Continuous ambulatory peritoneal dialysis (CAPD) peritonitis is one of the common complications and direct causes of death in the majority of patients undergoing peritoneal dialysis. The laboratory plays an important role in the management of such patients by guiding definitive antimicrobial therapy. The purpose of the present study is to compare the culture positivity rate before and after implementation of revised International Society for Peritoneal Dialysis guidelines, 2016 as well as to study the etiology and antimicrobial susceptibility pattern of causative organisms in our center.

Materials and Methods:
This ambispective study was conducted in the Department of Microbiology in a tertiary care hospital in North India. A training session of laboratory staff on revised culture techniques of CAPD fluid was undertaken in March 2018. The CAPD fluids received from October 2017 to February 2018 and April to July 2018 were labeled as pre- and post-intervention groups, respectively.

Results:
Out of 70 samples received from the clinically suspected peritonitis episodes, 28 (40%) belonged to confirmed CAPD peritonitis cases. After the intervention, the culture negativity rate dropped from 68.7% to 8.3%. The rate of bacterial and fungal isolates was 87.5% and 12.5%, and most of the isolates showed low resistance to antimicrobials.

Conclusion:
The study highlights the importance of training laboratory staff on standard guidelines, which resulted in an increased culture positivity rate in CAPD fluids. Identification and antimicrobial susceptibility patterns of isolated pathogens will help the clinicians in initiating appropriate management.