bluuebunny/crossref_metadata_2025_split huggingface dataset:
A proximity based macro stress testing
framework
Authors: Waelchli Boris 
Published: November 2016

Abstract
In this a paper a non-linear macro stress testing methodology with focus on early warning is developed.
The methodology builds on a variant of Random Forests and its proximity measures. It is embedded
in a framework, in which naturally defined contagion and feedback effects transfer the impact of stressing a
relatively small part of the observations on the whole dataset, allowing to estimate a stressed future state. It
will be shown that contagion can be directly derived from the proximities while iterating the proximity based
contagion leads to naturally defined feedback effects. Since the methodology is Random Forests based the
framework can be estimated on large numbers of risk indicators up to big data dimensions, fostering the stability
of the results while reducing inaccuracies in estimated stress scenarios by only stressing a small part of
the observations. This procedure allows accurate forecasting of events under stress and the emergence of a
potential macro crisis. The framework also estimates a set of the most influential economic indicators leading
to the potential crisis, which can then be used as indications of remediation or prevention.
Some non-unique fixed point theorems of Ćirić type using rational-type contractive conditions
Authors: Olatinwo Memudu Olaposi 
Published: November 2016

Abstract
In this paper, we prove some fixed point theorems of Ćirić type for mappings having non-unique fixed points by employing rational-type contractive conditions and the notion of comparison functions. Our results are generalizations, extensions and improvements of some previous and corresponding results in the literature.
Safe Distance, Dark Tourism, and Ambivalent Spatial Relation in Gillian Plowman’s Yours Abundantly, From Zimbabwe, and Christine Evans’s Trojan Barbie
Authors: Dundar Eda Dedebas 
Published: November 2016

AbstractColonial adventures and imperialistic travels have taken a new pattern as in the cases of humanitarian travel and dark tourism in the twenty-first century. Dark tourism not only satisfies Western individual’s hunger for orientalism labeling the touristic site a marginal and exotic landscape, but also uncovers the touristic undercurrents involved in the voyage. In this article, by utilizing the immediacy of the theatre genre, I argue that dramatic literature shares similar ambivalent spatial relations with humanitarian travel in that they both locate themselves between proximity and remoteness in their relation to the other. Similarly, by staging metatheatrical aspects, Plowman’s
“A community of storytellers and translators”: Ubu and the Truth Commission
Authors: Planche Jill 
Published: November 2016

AbstractDoes the space of performance play a dynamic role in South Africa twenty years after the end of apartheid? Can theatre tell the stories that resonate in a landscape of ambiguity and uncertainty, where fragile and fractured memories remain concealed? The post-apartheid milieu produces a complex audience dislocated by spaces of inherited physical and mental boundaries. Theatre played an important oppositional role during apartheid. Now, the challenge for theatre is far more entangled and calls for theatre-making that heightens the community’s critical social and political reflection.
Synthesis and crystal structure of [2-(menthoxycarbonyl)ethyl]tris(8-quinolinato)tin
Authors: Tian Laijin , Zhang Shuai , Yao Yanze , Shi Xiaowen 
Published: November 2016

AbstractIn this study, [2-(Menthoxycarbonyl)ethyl]tris(8-quinolinato)tin, MenOCOCH
The crystal structure of 1-(4-bromophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)ethanol, C18H20BrFN2O1
Authors: Zhang Yang , Wang Su , Sun Juan 
Published: November 2016

Abstract
C18H20BrFN2O1, monoclinic, P21/c (no. 14), a = 14.1884(10) Å, b = 5.3673(4) Å, c = 22.3768(15) Å, β = 93.293(2)°, V = 1701.3(2) Å3, Z = 4, Rgt(F) = 0.0510, wRref(F2) = 0.1384, T = 273 K.
Applicability of biobased packaging materials for long shelf-life food products
Authors: Peelman Nanou , Ragaert Peter , Verguldt Elien , Devlieghere Frank , De Meulenaer Bruno 
Published: November 2016

AbstractThe research aim was to evaluate the applicability of biobased plastics for packing long shelf-life food products, both on laboratory and industrial scale. Therefore, the shelf-life (room temperature) of tortilla chips, dry biscuits and potato flakes packed under air or modified atmosphere (MAP) in xylan and cellulose-based packages was evaluated and compared with their shelf-life in reference (conventional) packaging materials. These tests were followed by packaging trials on industrial lines. Furthermore, overall migration studies and printability tests were performed. Most of the biobased packages showed sufficient barrier towards moisture and gasses to serve as a food packaging material and MAP packaging of long shelf-life food products is possible. But for very moisture-sensitive food products (e.g. dry biscuits), no suited packaging material was found. The quality of the tortilla chips and potato flakes could be guaranteed during their shelf-life, even if packaging materials with lower barrier properties were used. Still, brittleness and seal properties are critical for use on industrial scale (important for use on vertical flow packaging machines). Furthermore, the films were printable and migration tests showed compliance with legislation. This study shows promising results towards the industrial application of biobased packaging materials for long shelflife food products.
Genealogie als intertextuelles Spiel
Authors: Schollmeyer Jonas 
Published: November 2016

AbstractIn Book 1 of theArgonautica, Apollonios Rhodios counts out the names of 55 heroes who set off to win the Golden Fleece. All the heroes are given genealogical details that often contribute to their characterisation. Only Admetus’ γενεή is passed over in silence by the catalogue. This was noted already by H. Fränkel, who suspected a lacuna in the text. However, there is another solution to the problem. The distinctive relationship of Admetus to his parents is detailed nowhere more clearly and drastically than in Euripides’Alcestis. In what is perhaps the most bitter agon in Greek tragedy, the father and son quarrel so severely that Admetus throws his parents out of the house and from then on wishes not to be regarded as their son. Apollonios assumes a knowledge of this famous quarrel among his readers or hearers, and he shows the sad consequences of this unreconciled generational conflict by breaking the convention of filiation and silently calling to mind the unresolved problems of theAlcestis.
The Problem of the Instrument Stabilization During Hydrographic Measurements
Authors: Felski Andrzej , Naus Krzysztof , Wąż Mariusz 
Published: November 2016

Abstract
Performing any measurement on watercraft is connected with many additional difficulties caused by the sea-environment. The most important is the problem of spatial stabilization of measurement systems, which are usually fastened to craft body. As soon as usually these measurement are executed during the move of the craft additional question is the accuracy of execution the planed trajectory.
This is a problem for all investigators, especially when system use spatially configured beams of any antennas or other sensors, regardless is it receiving or transmitting one.
Different aspects of these question are the subject of research activity of Institute of Navigation and Maritime Hydrography of Polish Naval Academy. In this paper the review of works executed in last years are presented.
Geodetic and Geodynamic Studies at Department of Geodesy and Geodetic Astronomy Wut
Authors: Brzeziński Aleksander , Barlik Marcin , Andrasik Ewa , Izdebski Waldemar , Kruczyk Michał , Liwosz Tomasz , Olszak Tomasz , Pachuta Andrzej , Pieniak Magdalena , Próchniewicz Dominik , Rajner Marcin , Szpunar Ryszard , Tercjak Monika , Walo Janusz 
Published: November 2016

Abstract
The article presents current issues and research work conducted in the Department of Geodesy and Geodetic Astronomy at the Faculty of Geodesy and Cartography at Warsaw University of Technology. It contains the most important directions of research in the fields of physical geodesy, satellite measurement techniques, GNSS meteorology, geodynamic studies, electronic measurement techniques and terrain information systems.
Vasculo-Neuronal Coupling: Retrograde Vascular Communication to Brain Neurons
Authors: Kim Ki Jung , Ramiro Diaz Juan , Iddings Jennifer A. , Filosa Jessica A. 
Published: November 2016

Continuous cerebral blood flow is essential for neuronal survival, but whether vascular tone influences resting neuronal function is not known. Using a multidisciplinary approach in both rat and mice brain slices, we determined whether flow/pressure-evoked increases or decreases in parenchymal arteriole vascular tone, which result in arteriole constriction and dilation, respectively, altered resting cortical pyramidal neuron activity. We present evidence for intercellular communication in the brain involving a flow of information from vessel to astrocyte to neuron, a direction opposite to that of classic neurovascular coupling and referred to here as vasculo-neuronal coupling (VNC). Flow/pressure increases within parenchymal arterioles increased vascular tone and simultaneously decreased resting pyramidal neuron firing activity. On the other hand, flow/pressure decreases evoke parenchymal arteriole dilation and increased resting pyramidal neuron firing activity. InGLAST-CreERT2;R26-lsl-GCaMP3mice, we demonstrate that increased parenchymal arteriole tone significantly increased intracellular calcium in perivascular astrocyte processes, the onset of astrocyte calcium changes preceded the inhibition of cortical pyramidal neuronal firing activity. During increases in parenchymal arteriole tone, the pyramidal neuron response was unaffected by blockers of nitric oxide, GABAA, glutamate, or ecto-ATPase. However, VNC was abrogated by TRPV4 channel, GABAB, as well as an adenosine A1receptor blocker. Differently to pyramidal neuron responses, increases in flow/pressure within parenchymal arterioles increased the firing activity of a subtype of interneuron. Together, these data suggest that VNC is a complex constitutive active process that enables neurons to efficiently adjust their resting activity according to brain perfusion levels, thus safeguarding cellular homeostasis by preventing mismatches between energy supply and demand.SIGNIFICANCE STATEMENTWe present evidence for vessel-to-neuron communication in the brain slice defined here as vasculo-neuronal coupling. We showed that, in response to increases in parenchymal arteriole tone, astrocyte intracellular Ca2+increased and cortical neuronal activity decreased. On the other hand, decreasing parenchymal arteriole tone increased resting cortical pyramidal neuron activity. Vasculo-neuronal coupling was partly mediated by TRPV4 channels as genetic ablation, or pharmacological blockade impaired increased flow/pressure-evoked neuronal inhibition. Increased flow/pressure-evoked neuronal inhibition was blocked in the presence of adenosine A1 receptor and GABABreceptor blockade. Results provide evidence for the concept of vasculo-neuronal coupling and highlight the importance of understanding the interplay between basal CBF and resting neuronal activity.
Comorbidities, treatment patterns and cost-of-illness of acromegaly in Sweden: a register-linkage population-based study
Authors: Lesén Eva , Granfeldt Daniel , Houchard Aude , Dinet Jérôme , Berthon Anthony , Olsson Daniel S , Björholt Ingela , Johannsson Gudmundur 
Published: November 2016

Objective
Acromegaly is a complex endocrine disease with multiple comorbidities. Treatment to obtain biochemical remission includes surgery, medical therapy and radiation. We aimed to describe comorbidities, treatment patterns and cost-of-illness in patients with acromegaly in Sweden.

Design
A nationwide population-based study.

Methods
Patients with acromegaly were identified and followed in national registers in Sweden. Longitudinal treatment patterns were assessed in patients diagnosed between July 2005 and December 2013. The cost-of-illness during 2013 was estimated from a societal perspective among patients diagnosed between 1987 and 2013.

Results
Among 358 patients with acromegaly (48% men, mean age at diagnosis 50.0 (s.d. 15.3) years) at least one comorbidity was reported in 81% (n = 290). The most common comorbidities were hypertension (40%, n = 142), neoplasms outside the pituitary (30%, n = 109), hypopituitarism (22%, n = 80) and diabetes mellitus (17%, n = 61). Acromegaly treatment was initiated on average 3.7 (s.d. 6.9) months after diagnosis. Among the 301 treated patients, the most common first-line treatments were surgery (60%, n = 180), somatostatin analogues (21%, n = 64) and dopamine agonists (14%, n = 41). After primary surgery, 24% (n = 44) received somatostatin analogues. The annual per-patient cost was €12 000; this was €8700 and €16 000 if diagnosed before or after July 2005, respectively. The cost-of-illness for acromegaly and its comorbidities was 77% from direct costs and 23% from production loss.

Conclusions
The prevalence of comorbidity is high in patients with acromegaly. The most common first-line treatment in acromegalic patients was surgery followed by somatostatin analogues. The annual per-patient cost of acromegaly and its comorbidities was €12 000.
Silent somatotroph tumour revisited from a study of 80 patients with and without acromegaly and a review of the literature
Authors: Chinezu Laura , Vasiljevic Alexandre , Trouillas Jacqueline , Lapoirie Marion , Jouanneau Emmanuel , Raverot Gérald 
Published: November 2016

Background
Silent somatotroph tumours are growth hormone (GH) immunoreactive (IR) pituitary tumours without clinical and biological signs of acromegaly. Their better characterisation is required to improve the diagnosis.

Materials and methods
Twenty-one silent somatotroph tumours were compared to 59 somatotroph tumours with acromegaly. Tumours in each group were classified into GH and plurihormonal (GH/prolactin (PRL)/±thyroid-stimulating hormone (TSH)) and into densely granulated (DG) and sparsely granulated (SG) types. The two groups were then compared with regards to proliferation (Ki-67, p53 indexes and mitotic count), differentiation (expression of somatostatin receptors SSTR2A–SSTR5 and transcription factor Pit-1) and secretory activity (% of GH- and PRL-IR cells).

Results
The silent somatotroph tumours represented 2% of all tested pituitary tumours combined. They were more frequent in women than in men (P = 0.002), more frequently plurihormonal and SG (P < 0.01), with a lower percentage of GH-IR cells (P < 0.0001) compared to those with acromegaly. They all expressed SSTR2A, SSTR5 and Pit-1. The plurihormonal (GH/PRL/±TSH) tumours were mostly observed in women (sex ratio: 3/1) and in patients who were generally younger than those with acromegaly (P < 0.001). They were larger (P < 0.001) with a higher Ki-67 index (P = 0.007).

Conclusions
The silent somatotroph tumours are not uncommon. Their pathological diagnosis requires the immunodetection of GH and Pit-1. They are more frequently plurihormonal and more proliferative than those with acromegaly. A low secretory activity of these tumours might explain the normal plasma values for GH and insulin-like growth factor 1 (IGF1) and the absence of clinical signs of acromegaly.
Microencapsulación mediante secado por aspersión de aceite de mora (Rubus glaucus) extraido con CO2 supercrítico
Authors: Figueroa Martínez Paola Milena , Hurtado Benavides Andrés Mauricio , Ceballos Ortíz Miguel Angel 
Published: November 2016

El aceite de mora es un ingrediente natural con potencial en la industria cosmética y alimentaria, a su vez puede experimentar degradación oxidativa en condiciones ambientales. Por ello, se extrajo aceite a partir de semillas de mora empleando fluidos supercríticos y, posteriormente, se microencapsuló mediante secado por aspersión y se evaluó la influencia de diferentes condiciones de operación en el rendimiento, y la eficiencia del proceso. Se emplearon como materiales encapsulantes: masterdry, goma arábiga y maltodextrina. Se estudió el tamaño y morfología de las microcápsulas. Se determinó que en el proceso de microencapsulación la temperatura de entrada fue la única variable estadísticamente significativa que afectó el rendimiento y la eficiencia, cuando se usaron como encapsulantes masterdry y goma arábiga. El caudal de alimentación fue estadísticamente significativo sólo para el rendimiento del proceso y lo influenció negativamente cuando se usó maltodextrina. La goma arábiga resultó ser el mejor encapsulante entre los tres estudiados. Se obtuvieron microcápsulas con tamaños entre 8,2 y 14 μm, con superficie continua en las paredes y ausencia de poros. Se comprobó que la microencapsulación con los tres encapsulantes permitió proteger el aceite y conservar mayoritariamente su perfil de ácidos grasos.
PENGARUH Implantasi HCG PADA PERKEMBANGAN TELUR, Pematangan Akhir Gonad, dan Pemijahan Ikan Tor soro
Authors: Subagja Jojo , Gustiano Rudhy 
Published: November 2016

Penelitian tentang implantasi hormon Human Chorionic Gonadotropin (HCG) dengan tujuan untuk mengetahui pengaruhnya terhadap perkembangan pematangan akhir gonad dan pemijahan ikan Tor soro telah dilakukan di Instalasi Riset Plasma Nutfah Perikanan Budidaya Air Tawar, Cijeruk-Bogor. Perlakuan dosis hormon yang diimplantasikan adalah: 300; 400; 500 IU.Kg-1 bobot tubuh dan kontrol (tanpa hormon). Hasil penelitian menunjukkan ada perbedaan nyata antara perlakuan pada pengamatan ke 25 dan 50 hari setelah implantasi, yaitu pemberian pelet hormon dengan kadar 500 IU.kg-1 bobot tubuh, menghasilkan perkembangan diameter oosit paling besar dengan rataan diameter oosit 3,07 ± 0,31 mm dibandingkan dengan perlakuan lainnya, diikuti perlakuan kontrol, 300 IU.kg-1 bobot tubuh dan 400 IU.kg-1 bobot tubuh, dengan nilai rataan berturut-turut 2,11 ± 0,53 mm; 1,97 ± 0,55 mm; dan 0,87 ± 0,50 mm. Keberhasilan pemijahan pada dosis implan 500 IU. kg-1 bobot tubuh mencapai 100% dengan kisaran waktu laten antara 25 dan 27 jam dengan suhu inkubasi 22°C—24°C, serta larva normal berkembang mencapai 90,19%.Study aimed to identify the effect of Human Chorionic Gonadotropin hormone implantation on gonadal development, final maturation, and spawning of Tor soro was conducted at Research Instalation of Germ Plasm Cijeruk-Bogor. Experimental dosage of hormone treated were 300, 400, 500 IU kg-1 body weight and control (without hormonal treatment). The result showed a significant difference between each treatment observed at the 25th and 50 th day after implantation. Hormon pellet at dosage 500 IU kg-1 body weight produced the biggest oocytes with average diameter 3.07 ± 0.31 mm, and followed by control, 300 IU treatment and 400 IU treatment with average diameter were 2.11 ± 0.53 mm, 1.97 ± 0.55 mm and 0.87 ± 0.50 mm, respectively. Succesful spawning rate of Tor soro treated hormone pellet of 500 IU kg-1 body weight reached of 100% at latentcy time of 25—27 hour (incubation temperature of 22°C—24°C) and larvae developed normally of 90.19%.
DETEKSI GEN-GEN PENYANDI FAKTOR VIRULENSI PADA BAKTERI VIBRIO
Authors: Kadriah Ince Ayu Khairani , Susianingsih Endang , Sukenda Sukenda , Yuhana Munti , Harris Enang 
Published: November 2016

Penelitian untuk mendeteksi gen-gen penyandi virulensi dilakukan denganmenggunakan isolat bakteri yang diisolasi dari budidaya udang windu di berbagai daerah di Sulawesi Selatan dan Jawa. Pada penelitian ini digunakan primer spesifik untuk mendeteksi gen-gen virulen toxR gene, hemolysin (vvh) gene, dan GyrB gene dengan metode PCR. Dari 35 isolat yang diisolasi, 20 isolat terdeteksi memiliki gen virulensi dan 8 di antaranya memiliki dua gen virulen. Spesies bakteri yang memiliki gen virulen adalah: V.harveyi, V. parahaemolyticus, V. mimicus, dan V. campbelli
KIT ENZYME-LINKED IMMUNOSORBENT ASSAY UNTUK DETEKSI WSSV PADA UDANG
Authors: Madeali Mun Imah , Nurhidayah Nurhidayah 
Published: November 2016

Komponen dasar yang penting dan menentukan keberhasilan pengendalian suatu penyakit dalam bidang perikanan adalah informasi tentang patogen secara dini, cepat, dan akurat, serta epidemi penyakit di lapangan. Teknik serologi, khususnya ELISA, merupakan salah satu teknik yang menjanjikan untuk keperluan tersebut, karena relatif mudah dan murah, serta berpeluang untuk digunakan secara langsung di lapangan. Telah dilakukan uji lapang terhadap perangkat Kit ELISA yang telah diproduksi oleh Balai Riset Perikanan Budidaya Air Payau. Hasil uji lapang menunjukkan bahwa Kit ELISA dapat digunakan untuk mendeteksi penyakit WSSV pada udang windu, dengan waktu ± 3 jam untuk setiap kali pengujian mulai persiapan sampai pembacaan hasil uji. Hasil Kit ELISA lebih cepat dibandingkan dengan metode PCR yang memerlukan waktu 24 jam. Biaya yang diperlukan untuk mendeteksi satu sampel juga lebih ekonomis yaitu ± Rp 35.000,- dibandingkan dengan PCR (Rp 150.000,- – Rp 300.000,-) per sampel
PERTUMBUHAN DAN SINTASAN UDANG VANAME (Litopenaeus vannamei) DENGAN KOMBINASI PAKAN BERBEDA DALAM WADAH TERKONTROL
Authors: Tahe Suwardi , Suwoyo Hidayat Suryanto 
Published: November 2016

Pakan merupakan satu di antara faktor yang perlu diperhatikan dalam sistem budidaya udang di tambak, karena berpengaruh terhadap pertumbuhan, sintasan, dan efisiensi biaya produksi. Penelitian ini bertujuan untuk mengetahui kombinasi pakan yang tepat terhadap pertumbuhan dan sintasan udang vaname (Litopenaeus vannamei). Penelitian dilaksanakan di Instalasi Perbenihan Balai Riset Perikanan Budidaya Air Payau. Wadah yang digunakan adalah bak fiber glass ukuran 1 m x 1 m x 0,7 m sebanyak 9 buah. Setiap bak diisi air laut salinitas 32 ppt sebanyak 500 L dan dilengkapi 1 buah aerasi. Hewan uji yang digunakan adalah tokolan udang vaname dengan bobot rata-rata 0,45 g/ekor dan ditebar kepadatan 100 ekor/bak. Penelitian diset menggunakan Rancangan Acak Lengkap dengan 3 perlakuan yaitu: (A) pakan PV 100%, (B) pakan PV 75% + pakan EB 25%, dan (C) pakan PV 50% + EB 50%, masing-masing perlakuan diulang tiga kali. Selama pemeliharan 85 hari, udang diberi pakan dosis 50-5% dari total bobot biomassa/hari. Hasil penelitian yang diperoleh menunjukkan bahwa kombinasi pakan berpengaruh nyata (P<0,05) terhadap pertumbuhan, sintasan, rasio konversi pakan, dan produksi udang vaname. Pertumbuhan dan sintasan udang vaname terbaik yaitu masing-masing 6,31g dan 86% diperoleh pada perlakuan B bila dibanding perlakuan lainnya.