bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Computational Investigation of the Equilibrium Constants for the Fluorescent and Chemiluminescent States of Coelenteramide
Authors: Min Chun‐Gang , Pinto da Silva Luís , Esteves da Silva Joaquim C. G. , Yang Xi‐Kun , Huang Shao‐Jun , Ren Ai‐Min , Zhu Yan‐Qin 
Published: November 2016

AbstractIn spite of recent advances in understanding the mechanism of coelenterate bioluminescence, there is no consensus about which coelenteramide specie and/or state are the light emitter. In this study, a systematic investigation of the geometries and spectra of all possible light emitters has been performed at the TD ωB97XD/6‐31+G(d) level of theory, including various fluorescent and chemiluminescent states in vacuum, in a hydrophobic environment and in aqueous solution. To deduce the most probable form of the fluorescent and chemiluminescent coelenteramide emitter, the equilibrium constants for the fluorescent and chemiluminescent states connecting the various species have been calculated. ωB97XD gives a qualitatively good description of fluorescent and chemiluminescent structures. Coelenteramide is formed in a “dark” chemiluminescent state and must evolve to a bright fluorescent state. Moreover, the photoacidity of the phenol group is significantly higher in the fluorescent state than in the chemiluminescent state, which allows the formation of phenolate coelenteramide and clarifies its role as the bioluminescent emitter.
Tailored Fabrication of Transferable and Hollow Weblike Titanium Dioxide Structures
Authors: Hiltunen Arto , Lahtonen Kimmo , Saari Jesse , Ojanperä Anniina , Sarlin Essi , Wondraczek Holger , Efimov Alexander , Kaunisto Kimmo , Vivo Paola , Maccato Chiara , Barreca Davide , Fardim Pedro , Tkachenko Nikolai , Valden Mika , Lemmetyinen Helge 
Published: November 2016

AbstractThe preparation of weblike titanium dioxide thin films by atomic layer deposition on cellulose biotemplates is reported. The method produces a TiO2 web, which is flexible and transferable from the deposition substrate to that of the end application. Removal of the cellulose template by calcination converts the amorphous titania to crystalline anatase and gives the structure a hollow morphology. The TiO2 webs are thoroughly characterized using electron microscopy, X‐ray diffraction, and X‐ray photoelectron spectroscopy to give new insight into manufacturing of porous titanium dioxide structures by means of template‐based methods. Functionality and integrity of the TiO2 hollow weblike thin films were successfully confirmed by applying them as electrodes in dye‐sensitized solar cells.
Complete Conversion of PbI2 to Methyl Ammonium PbI3 Improves Perovskite Solar Cell Efficiency
Authors: Wang Lili , Lin Wei‐Chun , McCleese Christopher , Kovalsky Anton , Zhao Yixin , Burda Clemens 
Published: November 2016

AbstractOne major disadvantage to the two‐step deposition method of perovskite films is the incomplete conversion from PbI2 to perovskite resulting in the presence of a thick PbI2 layer, which hinders charge carrier transportation. In this study, a quaternary ammonium salt has been used to manipulate the crystallization of PbI2 in the first deposition step, which leads to facile incorporation of the methylammonium iodide into the Pb‐I lattice and promotes the conversion of PbI2 to perovskite leading to improved device performance.
Catalytic Macroporous Biohydrogels Made of Ferritin‐Encapsulated Gold Nanoparticles
Authors: Kumari Sushma , Häring Marleen , Gupta Sayam Sen , Díaz Díaz David 
Published: November 2016

AbstractReported is a modular approach for the incorporation and stabilization of gold nanoparticles inside a three‐dimensional macroporous hydrogel made of ferritin. The strategy, which involves the dynamic templating of surfactant H1 domains, demineralization, and remineralization helps to overcome aggregation and degradation issues usually associated with bare‐metal‐based nanocatalysts. The catalytic activity of the so‐synthesized bionanocomposite hydrogel was demonstrated in both nitroaldol (Henry) and nitroreduction model reactions in aqueous solution at room temperature. An interesting synergistic effect between basic residues of the protein and the gold nanoparticles was found in the nitroaldol reaction when carried out in water in the presence of a phase‐transfer catalyst. Furthermore, the reduction of 4‐nitrophenol and 4‐nitroaniline catalyzed by the nanocomposite scaffold in the presence of NaBH4 proceeded significantly faster than that using other known Au‐ and Ag‐based catalysts under similar conditions.
Discrimination of Octahedral versus Trigonal Bipyramidal Coordination Geometries of Homogeneous TiIV, VV, and MoVI Amino Triphenolate Complexes through Nitroxyl Radical Units
Authors: Badetti Elena , Lloveras Vega , Romano Francesco , Di Lorenzo Rosalia , Veciana Jaume , Vidal‐Gancedo José , Zonta Cristiano , Licini Giulia 
Published: November 2016

AbstractInvited for the cover of this issue is the group of Giulia Licini at Università di Padova, Italy, in collaboration with the NANOMOL research group at the Institute of Materials Science of Barcelona, Spain. The cover image shows the change in geometry of an amino triphenolate vanadium(V) complex, which is detected by EPR spectroscopy.
Vendor‐derived differences in injury‐induced pain phenotype and pharmacology of Sprague–Dawley rats: Does it matter?
Authors: Kristensen P.J. , Heegaard A.M. , Hestehave S. , Jeggo R.D. , Bjerrum O.J. , Munro G. 
Published: November 2016

AbstractBackgroundOutbred Sprague–Dawley (SD) rats are a commonly used strain in preclinical pain research. Here, we established empirically how SD rats obtained from different vendors might vary in sensitivity to injury and pharmacotherapy.MethodsChronic Constriction Injury (CCI) or complete Freund's adjuvant (CFA) hindpaw inflammation was induced in male SD rats sourced from three to four different vendors, respectively. Neuropathic hypersensitivity was evaluated over 58 days using von Frey filaments, pinprick stimulation and the hot plate test. Pharmacological sensitivity was evaluated by treatment with gabapentin (100 mg/kg, p.o.) or morphine (3 mg/kg, s.c.). CFA‐induced hyperalgesia and sensitivity to morphine (0.3–6 mg/kg, s.c.) was measured using a digital Randall–Selitto device. In addition, paw weight gain was used as an index of peripheral oedema.ResultsSignificant differences between the vendor‐supplied SD rats in relation to onset, magnitude and resolution of hypersensitivity after CCI were observed. Although all sub‐strains eventually developed a robust and reversible neuropathic hypersensitivity to mechanical stimulation, the thermal hypersensitivity varied. Whereas pharmacological response to gabapentin varied enormously, the response to morphine was both robust and much more consistent between sub‐strains. Despite a similar degree of CFA‐induced hypersensitivity, the paw oedema level differed between sub‐strains. Here, morphine dose‐dependently alleviated the CFA‐induced hypersensitivity, with only a subtle difference in sensitivity between sub‐strains observed.ConclusionsOur data reveal that the source of vendor used to obtain SD rats may be one key factor responsible for ‘between laboratory variation’ in reproducing sensitivity to some drugs targeting various pathophysiological mechanisms in specific animal pain models.SignificanceThe choice of vendor used to source the same strain of rat for use in preclinical pain research can profoundly affect the level of nociceptive hypersensitivity and response to reference analgesics in neuropathic versus inflammatory models.
An All‐solid‐state Polymeric Membrane Ca2+‐selective Electrode Based on Hydrophobic Alkyl‐chain‐functionalized Graphene Oxide
Authors: Yin Tanji , Li Jinghui , Qin Wei 
Published: November 2016

AbstractAn all‐solid‐state polymeric membrane Ca2+‐selective electrode based on hydrophobic octadecylamine‐functionalized graphene oxide has been developed. The hydrophobic composite in the ion‐selective membrane not only acts as a transduction element to improve the potential stability for the all‐solid‐state Ca2+‐selective electrode, but also is used to immobilize Ca2+ ionophore with lipophilic side chains through hydrophobic interactions. The developed all‐solid‐state Ca2+‐selective electrode shows a stable potential response in the linear range of 3.0×10−7–1.0×10−3 M with a slope of 24.7±0.3 mV/dec, and the detection limit is (1.6±0.2 )×10−7 M (n=3). Additionally, due to the hydrophobicity and electrical conductivity of the composite, the proposed all‐solid‐state ion‐selective electrode exhibits an improved stability with the absence of water layer between the ion‐selective membrane and the underlying glassy carbon electrode. This work provides a simple, efficient and low‐cost methodology for developing stable and robust all‐solid‐state ion‐selective electrode with ionophore immobilization.
Co2O3‐NH2‐MCM‐41 Decorated Graphite as an Effective Electrode: Synthesis, Characterization and its Application for Electro‐catalytic Oxidation of Acid Red 1
Authors: Fan Yiang , Wu Yunhai , Fang Peng , Sha Haitao , Cha Ligen , Ming Zhu 
Published: November 2016

AbstractThe graphite electrode decorated with Co2O3‐NH2‐MCM‐41 was successfully fabricated and the potential for applying this electrode for electro‐catalytic oxidation of Acid Red 1 (AR1) was investigated. The Co2O3‐NH2‐MCM‐41 was characterized by Scanning Electron Microscope (SEM), Brunauer‐Emmett‐Teller (BET), X‐ray diffraction (XRD) and Fourier transform infrared spectra (FTIR). Electrochemical measurements including cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were employed to investigate electrochemical activity of graphite anode with Co2O3‐NH2‐MCM‐41. The electro‐catalytic oxidation process was carried out via varying different parameters such as voltage, electrolyte pH, electrolyte concentration, current density and interelectrode distance. The results revealed the maximum removal ratio of AR1 was 99.8 %. The AR1 solution was tested during the degradation process by CV analysis at different scan rates, UV‐Vis spectral analysis and gas chromatography−mass spectrometry (GC/MS). The linear relationship between peak current and scan rates indicated an adsorption controlled process for AR1 degradation, UV‐Vis analysis revealed that the degradation process took place through reactions such as destruction of azo groups, benzene ring, naphthalene ring and so on, GC/MS analysis demonstrated that AR1 was finally destructed to small molecules by analyzing intermediates during degradation process.
A Printed and Microfabricated Sensor Device for the Sensitive Low Volume Measurement of Aqueous Ammonia
Authors: Brannelly N. T. , Killard A. J. 
Published: November 2016

AbstractThe measurement of low concentrations of ammonia in small sample volumes is required in biological, biomedical and environmental measurement applications. However, achieving this without instrumentation remains challenging. Here, sensor devices for the measurement of ammonia in a liquid were developed. These were based on the fabrication of polyaniline nanoparticle films onto screen printed interdigitated electrodes using inkjet printing and their integration into a polymer microfabricated device with polytetrafluroethylene membrane and air flow path between the membrane and the sensor. Samples of ammonia in phosphate buffered saline of 52 μL were measured using electrochemical impedance. While water vapour and ions from the buffer did result in a decrease in sensor impedance, this was eradicated by displacement of the headspace above the sensor with air. This, in combination with the adjustment of the sample to pH to 11 allowed the quantification of ammonia from 0 to 200 μM with a limit of detection of 25 μM. The device has the potential to be used for sensitive, low volume measurement applications of ammonia at point‐of‐test and point‐of‐care.
A Polymer Multilayer Based Amperometric Biosensor for the Detection of Lactose in the Presence of High Concentrations of Glucose
Authors: Lopez Francesca , Ma Su , Ludwig Roland , Schuhmann Wolfgang , Ruff Adrian 
Published: November 2016

AbstractWe report on the development of an amperometric polymer multilayer‐based biosensor for the determination of lactose in the presence of high concentrations of glucose. The sensor platform consists of a two‐layer system with the first layer (sensing layer) comprising cellobiose dehydrogenase (CDH) bound by electrostatic interactions in a favourite orientation for efficient direct electron transfer. The second layer on top of the sensing element consists of a specifically designed hydrophilic polymer which co‐entraps glucose oxidase (GOx) and catalase (CAT). This bi‐enzymatic system is able to remove glucose (up to a concentration of at least 140 mM) in the outer layer of the modified electrode and thus prevents the interfering analyte from reaching the active CDH layer. Moreover, the concomitantly generated H2O2 is efficiently removed by means of CAT. The linear range for the detection of lactose was from 10 to 100 μM. The sensor is able to detect lactose at low concentrations in lactose‐free milk samples. Sample pre‐treatment consist of a simple dilution step. Quantification of the lactose content in lactose‐free dairy products showed that the amount of lactose is below the threshold given by the manufacturer.
A Fast Electrochemical Quartz Crystal Microbalance,which Acquires Frequency and Bandwidth on Multiple Overtones
Authors: Petri Judith , Hochstädt Sebastian , Nentwig Tristan , Pausch Ansgar , Langhoff Arne , Johannsmann Diethelm 
Published: November 2016

AbstractAn electrochemical quartz crystal microbalance (EQCM) is described, which measures the shifts of frequency and bandwidth on multiple harmonics with a time‐resolution of 10 milliseconds. The technique requires the process under study to be repetitive. Examples are square wave amperometry and cyclovoltammetry. Data acquisition is fast because the raw data consist of traces of the electrical admittance at fixed frequencies. A few (∼10) such time traces are acquired sequentially at a set of frequencies evenly spaced around the crystal's resonance. Since all time‐traces are triggered by the same repetitive process, plots of the conductance G(ωi, t) and the susceptance B(ωi, t) from constant time delays, t, versus frequency can be produced a posteriori. The shifts, ΔG(ωi) and ΔB(ωi) quantify a difference between two resonance curves, pertaining to the sample's reference state and the state at time t. Fitting a difference of two resonance curves to these data, one obtains shifts of frequency, Δf(t) and shifts of bandwidth, ΔΓ(t), versus time. This procedure is repeated for the different overtones. Given the repetitive nature of the process, one may accumulate and average, which lowers the noise down to a few tens of mHz. The capabilities of this instrument are demonstrated with two examples, which are copper deposition/dissolution and electro‐responsivity of a polymer film containing weakly acidic side groups.
Association between depression and resilience in older adults: a systematic review and meta‐analysis
Authors: Wermelinger Ávila Maria Priscila , Lucchetti Alessandra Lamas Granero , Lucchetti Giancarlo 
Published: November 2016

ObjectiveThe objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations.MethodA systematic review and meta‐analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta‐analysis recommendations on three databases (PubMed/Medline, Scopus, and Web of Science) with no language restrictions, using a Boolean expression. For inclusion in the study, articles had to assess the older population (60 years or older), assess both depressive and resilience symptoms, and investigate the association between these two variables. Articles not employing validated resilience and depression scales or assessing populations younger than 60 years were excluded. The quality of the selected studies was assessed using the Quality Assessment Tool for Quantitative Studies.ResultsA total of 1094 articles were retrieved from the three databases, 367 of which were duplicates and therefore excluded, giving 727 articles for analysis. Of these articles, seven met the eligibility criteria. All of the included articles were observational and cross‐sectional, found an inverse relationship between depression and resilience, and were conducted in three countries: the USA, China, and Belgium. A moderate inverse correlation was found on the meta‐analysis (r = −0.35, 95% confidence interval: −0.41 to −0.28).ConclusionFew studies were found on this subject in the older population. An association between greater resilience and less depressive symptomatology was identified, albeit based on cross‐sectional studies. These results highlight the need for further studies in the area and the importance of fostering the use of interventions to promote resilience in older adults as a means of preventing and managing depressive symptoms in this population. Copyright © 2016 John Wiley & Sons, Ltd.
A COMMUNITY MENTAL HEALTH PROFESSIONAL DEVELOPMENT MODEL FOR THE EXPANSION OF REFLECTIVE PRACTICE AND SUPERVISION: EVALUATION OF A PILOT TRAINING SERIES FOR INFANT MENTAL HEALTH PROFESSIONALS
Authors: Shea Sarah E. , Goldberg Sheryl , Weatherston Deborah J. 
Published: November 2016

ABSTRACTThe Michigan Association for Infant Mental Health identified a need for reflective supervision training for infant mental health (IMH) specialists providing home‐based services to highly vulnerable infants and their families. Findings indicate that this pilot of an IMH community mental health professional development model was successful, as measured by the participants’ increased capacity to apply reflective practice and supervisory knowledge and skills. Furthermore, IMH clinicians demonstrated an increase in the frequency of their use of reflective practice skills, and their supervisors demonstrated an increase in their sense of self‐efficacy regarding reflective supervisory tasks. Finally, the evaluation included a successful pilot of new measures designed to measure reflective practice, contributing to the growing body of research in the area of reflective supervision.
In vivo terahertz reflection imaging of human scars during and after the healing process
Authors: Fan Shuting , Ung Benjamin S. Y. , Parrott Edward P. J. , Wallace Vincent P. , Pickwell‐MacPherson Emma 
Published: November 2016

We use terahertz imaging to measure four human skin scars in vivo. Clear contrast between the refractive index of the scar and surrounding tissue was observed for all of the scars, despite some being difficult to see with the naked eye. Additionally, we monitored the healing process of a hypertrophic scar. We found that the contrast in the absorption coefficient became less prominent after a few months post‐injury, but that the contrast in the refractive index was still significant even months post‐injury. Our results demonstrate the capability of terahertz imaging to quantitatively measure subtle changes in skin properties and this may be useful for improving scar treatment and management.
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Prevalence and clinical impact of cachexia in chronic illness in Europe, USA, and Japan: facts and numbers update 2016
Authors: von Haehling Stephan , Anker Markus S. , Anker Stefan D. 
Published: November 2016

AbstractCachexia is a serious clinical consequence of almost all chronic diseases when reaching advanced stages. Its prevalence ranges from 5–15% in end‐stage chronic heart failure to 50–80% in advanced malignant cancer. Cachexia is also frequently occurring in patients with chronic kidney disease, chronic obstructive pulmonary disease (COPD) or neurological diseases, and rheumatoid arthritis. Mortality rates of patients with cachexia range from 15–25% per year in severe COPD through 20–40% per year in patients with chronic heart failure or chronic kidney disease to 20–80% in cancer cachexia. In the industrialized world (North America, Europe, and Japan) where epidemiological data are to some degree available, the overall prevalence of cachexia (due to any disease and not necessarily associated with hospital admission) is growing with the growth of the chronic illness prevalence, and it currently affects around 0.5–1.0% of the population, i.e. around 6–12 million people. From this, one can estimate that 1.5–2 million deaths are occurring in patients with cachexia per year. It is also a very significant health problem in other parts of the globe, but epidemiological data are scarce. The multifactorial nature of cachexia is now much better understood, and particularly, the role of inflammatory mediators and the imbalance of anabolism and catabolism are considered important therapeutic targets. Several approaches to develop cachexia and muscle wasting treatments have failed to be successful in phase III clinical trials, but new approaches are in development. Given the high prevalence and very high mortality associated with cachexia, advances are urgently needed for patients worldwide.
The different paths to post‐merger identification for employees from high and low status pre‐merger organizations
Authors: Lipponen Jukka , Wisse Barbara , Jetten Jolanda 
Published: November 2016

SummaryA well‐known downside of organizational mergers is that employees fail to identify with the newly formed organization. We argue that developing an understanding of factors that affect post‐merger identification requires taking the pre‐merger status of the merger partners relative to each other into account. This is because relative pre‐merger status determines employees' susceptibility to different aspects of the merger process. Specifically, for employees of a high status pre‐merger organization, we expected post‐merger identification to be strongly influenced by (i) pre‐merger identification and (ii) the perceived change in the status. In contrast, we expected post‐merger identification of employees of a low status pre‐merger organization to be strongly affected by the perceived justice of the merger event. Longitudinal data were obtained from a merger of two public sector organizations and the results supported our hypotheses. Our study shows that the extent to which pre‐merger identification, status change, and justice are important determinants of post‐merger identification depends on the relative pre‐merger status of the merger partners. Our discussion focuses on theoretical implications and managerial ramifications of these findings. Copyright © 2016 John Wiley & Sons, Ltd.
Selective solid‐phase extraction using a molecularly imprinted polymer for the analysis of patulin in apple‐based foods
Authors: Lucci Paolo , Moret Sabrina , Bettin Sara , Conte Lanfranco 
Published: November 2016

The aim of this work was to evaluate the use of a molecularly imprinted polymer as a selective solid‐phase extraction sorbent for the clean‐up and pre‐concentration of patulin from apple‐based food products. Ultra high pressure liquid chromatography coupled to ultraviolet absorbance detection was used for the analysis of patulin. The molecularly imprinted polymer was applied, for the first time, to the determination of patulin in apple juice, puree and jam samples spiked within the maximum levels specified by the European Commission No. 1881/2006. High recoveries (>77%) were obtained. The method was validated and found to be linear in the range 2–100 μg/kg with correlation coefficients greater than 0.965 and repeatability relative standard deviation below 11% in all cases. Compared with dispersive solid‐phase extraction (QuEChERS method) and octadecyl sorbent, the molecularly imprinted polymer showed higher recoveries and selectivity for patulin.The application of Affinisep molecularly imprinted polymer as a selective sorbent material for detection of patulin fulfilled the method performance criteria required by the Commission Regulation No. 401/2006, demonstrating the suitability of the technique for the control of patulin at low ppb levels in different apple‐based foods such as juice, puree and jam samples.