bluuebunny/crossref_metadata_2025_split huggingface dataset:
Saccharomyces cerevisiae FLO1Gene Demonstrates Genetic Linkage to Increased Fermentation Rate at Low Temperatures
Authors: Deed Rebecca C , Fedrizzi Bruno , Gardner Richard C 
Published: February 2017

AbstractLow fermentation temperatures are of importance to food and beverage industries working with Saccharomyces cerevisiae. Therefore, the identification of genes demonstrating a positive impact on fermentation kinetics is of significant interest. A set of 121 mapped F1 progeny, derived from a cross between haploid strains BY4716 (a derivative of the laboratory yeast S288C) and wine yeast RM11-1a, were fermented in New Zealand Sauvignon Blanc grape juice at 12.5°. Analyses of five key fermentation kinetic parameters among the F1 progeny identified a quantitative trait locus (QTL) on chromosome I with a significant degree of linkage to maximal fermentation rate (Vmax) at low temperature. Independent deletions of two candidate genes within the region, FLO1 and SWH1, were constructed in the parental strains (with S288C representing BY4716). Fermentation of wild-type and deletion strains at 12.5 and 25° confirmed that the genetic linkage to Vmax corresponds to the S288C version of the FLO1 allele, as the absence of this allele reduced Vmax by ∼50% at 12.5°, but not at 25°. Reciprocal hemizygosity analysis (RHA) between S288C and RM11-1a FLO1 alleles did not confirm the prediction that the S288C version of FLO1 was promoting more rapid fermentation in the opposing strain background, suggesting that the positive effect on Vmax derived from S288C FLO1 may only provide an advantage in haploids, or is dependent on strain-specific cis or trans effects. This research adds to the growing body of evidence demonstrating the role of FLO1 in providing stress tolerance to S. cerevisiae during fermentation.
The Saccharomyces cerevisiae Cdk8 Mediator Represses AQY1 Transcription by Inhibiting Set1p-Dependent Histone Methylation
Authors: Law Michael J , Finger Michael A 
Published: February 2017

Abstract
In the budding yeast Saccharomyces cerevisiae, nutrient depletion induces massive transcriptional reprogramming that relies upon communication between transcription factors, post-translational histone modifications, and the RNA polymerase II holoenzyme complex. Histone H3Lys4 methylation (H3Lys4 me), regulated by the Set1p-containing COMPASS methyltransferase complex and Jhd2p demethylase, is one of the most well-studied histone modifications. We previously demonstrated that the RNA polymerase II mediator components cyclin C-Cdk8p inhibit locus-specific H3Lys4 3me independently of Jhd2p. Here, we identify loci subject to cyclin C- and Jhd2p-dependent histone H3Lys4 3me inhibition using chromatin immunoprecipitation (ChIP)-seq. We further characterized the independent and combined roles of cyclin C and Jhd2p in controlling H3Lys4 3me and transcription in response to fermentable and nonfermentable carbon at multiple loci. These experiments suggest that H3Lys4 3me alone is insufficient to induce transcription. Interestingly, we identified an unexpected role for cyclin C-Cdk8p in repressing AQY1 transcription, an aquaporin whose expression is normally induced during nutrient deprivation. These experiments, combined with previous work in other labs, support a two-step model in which cyclin C-Cdk8p mediate AQY1 transcriptional repression by stimulating transcription factor proteolysis and preventing Set1p recruitment to the AQY1 locus.
PENGARUH KEMUDAHAN PENGGUNAAN, KEMANFAATAN, SIKAP, RISIKO DAN FITUR LAYANAN TERHADAP MINAT ULANG NASABAH BANK BCA DALAM MENGGUNAKAN INITERNET BANKING
Authors: Rithmaya Chitra Laksmi 
Published: February 2017

ABSTRACT The use of Internet as a shopping medium has started to become popular nowadayd. Banking service providers also need to predict the acceptance of the Internet by consumers, and understand why they do such use. This opportunity is used by banks in Indonesia, both government and private banks, because Internet as a media is an innovation that is enough to give the opportunities and challenges in its development. Development of services performed by technology based banking (electronic transaction) in the form of internet banking, mobile based mobile banking (phone banking), the use of ATM (authomatic Teller Machine), Credit Card and others are compulsory for banks in Indonesia to grab market share. Nowadays, internet banking is a major concern and a revolutionary weapon of strategic operations of the bank, for delivering as well as for competing among banks. The problem in this study is whether there are influences of ease of ease of use, usefulness, the attitude of use, risks and service features variables towards the reset interest of the customers of Bank BCA Internet banking. The data used in this study were primary data obtained by distributing questionnaires to customers who use internet banking. By using multiple linear regression analysis, in a simultaneous test using the F test, shown the influence of the independent variables with the dependent variable. Partially, expediency variable (X2) influenced positively and had significant impact on The interest. Partially, attitudinal variables (X3) influenced Positively and had significant impact on the reset interest Partially, risk variable (X4) influenced positively and had Significant impact on the interest. Partially, service features Variables (X5) influenced positively and had significant impact on the reset interest.
THE IMPORTANCE OF COMMUNICATION IN THE TRANSFER OF KNOWLEDGE AND IN THE CREATION OF A SHARED VISION - A CASE STUDY
Authors: Angeloni Maria Terezinha , Homma Rafael Zimmermann , Athayde Filho Luiz Afonso Pereira , Cosentino Aldo 
Published: February 2017

Este artigo tem por objetivo apresentar o Plano de Comunicação, que visa a apoiar a transferência de conhecimento e a criação de uma visão compartilhada entre os integrantes de um Projeto de Pesquisa e Desenvolvimento. O referencial teórico baseia-se nas áreas da Gestão de Projetos, Gestão do Conhecimento e Comunicação Organizacional. Metodologicamente caracteriza-se como uma pesquisa experimental, intraprojeto e interorganizacional. Os resultados ainda não são efetivos em razão do pouco tempo de implantação do projeto; contudo, com base nas ações já implantadas, pode-se inferir que a Comunicação é um elemento importante na transferência do conhecimento e na criação de uma visão compartilhada.
Proposal for improved mixes to produce concrete masonry units with commonly used aggregates available in the Valley of Mexico
Authors: Tena A. , Liga A. , Pérez A. , González F. 
Published: February 2017

Proposal for improved mixes to produce concrete masonry units with commonly used aggregates available in the Valley of MexicoABSTRACTIn this paper, a proposal is done to update the masonry index compressive strength design value f*m for solid concrete masonry units for the masonry guidelines of Mexico´s Federal District Code (NTCM-2004). Solid units were made by taking into account the characteristics of the most commonly used raw materials available in the Valley of Mexico to fabricate such units in the Metropolitan Area of Mexico City. Different tests were conducted for both raw materials and the obtained concrete units. Based upon test results, it is illustrated why it is much better to design masonry structures based upon the experimental data of the units to be used at the construction site rather than using index values proposed in building codes.Keywords: masonry; concrete masonry units; compressive strength.Propuesta de mejora de mezclas para producir piezas de mampostería de concreto empleando materiales comúnmente disponibles en el Valle de MéxicoRESUMENSe presenta un estudio donde se hace una propuesta para actualizar los valores índices de la resistencia a la compresión de mamposterías (f*m) elaboradas con piezas de concreto especificados en las normas de mampostería vigentes en el Distrito Federal. Se realizó un estudio de mercado, donde se tomaron en cuenta las características de los materiales comúnmente utilizados en la actualidad en el Valle de México para la fabricación de piezas de concreto sólidas, incluyendo los resultados de distintas pruebas de laboratorio realizadas a la materia prima. Con base en estos resultados, se ilustran las ventajas de diseñar a la mampostería con base experimental en lugar de utilizar los valores indicativos que se ofrecen en las normas de mampostería.Palabras clave: mampostería; piezas de concreto; resistencia a la compresión. Proposta de melhoria de traços para produzir blocos de alvenaria de concreto utilizando materiais comumente disponíveis no Vale do México RESUMOApresenta-se um estudo onde se propõe uma atualização dos valores do índice de resistência à compressão da alvenaria (f*m) elaborados com blocos de concreto especificados nas normas de alvenaria em vigor no Distrito Federal. Foi realizado um estudo de mercado, que levou em conta as características dos materiais comumente utilizados atualmente no Vale do México para a fabricação de blocos de concreto sólidos, incluindo os resultados de vários testes de laboratório nas matérias-primas disponíveis. Com base nestes resultados, são apresentadas as vantagens de projetar a alvenaria com base experimental em lugar de usar os valores indicativos oferecidos nas normas de alvenaria.Palavras chave: alvenaria; blocos de concreto; resistência à compressão.
Damage assessment in concrete structures using piezoelectric based sensors
Authors: Narayanan A. , Subramaniam K. V. L. 
Published: February 2017

Damage assessment in concrete structures using piezoelectric based sensorsABSTRACTPiezoelectric based PZT (Lead Zirconate Titanate) smart sensors offer significant potential for continuously monitoring the development and progression of internal damage in concrete structures. Changes in the resonant behavior in the measured electrical conductance obtained from electro-mechanical (EM) response of a PZT bonded to a concrete substrate is investigated for increasing levels of damage. Changes in the conductance resonant signature from EM conductance measurements are detected before visible signs of cracking. The root mean square deviation of the conductance signature at resonant peaks is shown to accurately reflect the level of damage in the substrate. The findings presented here provide a basis for developing a sensing methodology using PZT patches for continuous monitoring of concrete structures.Keywords: PZT; electro-mechanical impedance; conductance; microcracks.Evaluación de daños en estructuras de concreto utilizando sensores piezoeléctricosRESUMENLos sensores inteligentes PZT (Lead Zirconate Titanate) basados en piezoeléctricos ofrecen un potencial significativo para monitorear continuamente el desarrollo y la progresión de los daños internos en estructuras de concreto. Se investigan los cambios en el comportamiento resonante a través de la conductancia eléctrica medida, obtenida a partir de la respuesta electromecánica (EM) de un PZT unido a un sustrato de concreto para aumentar los niveles de daño. Los cambios en la resonancia de la conductancia EM se detectan antes de que aparezcan signos visibles de agrietamiento. La desviación cuadrática media de la raíz de la conductancia en los picos resonantes refleja con precisión el nivel de daño en el sustrato. Los hallazgos presentados aquí proporcionan una base para desarrollar una metodología de detección utilizando parches PZT para el monitoreo continuo de estructuras de concreto.Palabras clave: PZT; impedancia electromecánica; conductancia; microfisuras.Avaliação de danos em estruturas de concreto usando sensores piezoelétricos RESUMOOs sensores piezoelétricos inteligentes PZT (Lead Zirconate Titanate) oferecem um potencial significativo para o monitoramento contínuo do desenvolvimento e progressão de danos internos em estruturas de concreto. As alterações de ressonância através da medida da condutância elétrica obtida a partir da resposta eletromecânica (EM) de um PZT ligado a um substrato de concreto é investigada para níveis crescentes de danos. As alterações no perfil de ressonância de condutância EM são detectadas antes de sinais visíveis de fissuras. O desvio quadrático médio da raiz do perfil de condutância nos picos ressonantes é mostrado para refletir com precisão o nível de dano no substrato. Os resultados aqui apresentados fornecem uma base para o desenvolvimento de uma metodologia de detecção usando PZT para monitoramento contínuo de estruturas de concretoPalavras chave: PZT; impedância eletromecânica; condutância; microfissuras.
Industry and Academia Continue Working on Big Ideas for Nanotechnology
Authors: Jacobs Trent 
Published: February 2017

The nanotechnologies enjoying commercial success in the oil field today are small in number, and for the most part, can be categorized as single-well applications. Examples include the dissolvable ball-drop systems used in horizontal well completions and the specialty additives operators are using to enhance drilling fluids.
The next big leap for this area of emerging technology will be the development of nanoparticles that work on larger scales, either in production operations or for fluid treatment.
Counted among the industry’s nanopioneers, Saudi Aramco is getting closer to the deployment of nanoparticles for a number of reservoir-wide applications. Others are working on creating nanoparticles that will improve the performance of waterflooding, and university researchers in Texas are developing a magnetic nanoparticle that aims to make offshore water treatment more efficient, and possibly more economic.
These concepts were presented at SPE’s Annual Technology Conference and Exhibition held last year in Dubai. Taken together, they offer a small, yet compelling, sample of the ideas still working their way through the pipeline.
Kirk Rainey, the vice president of A&I Ventures in Houston and a former chemical-enhanced oil recovery expert at Shell, has been involved with nanotechnology consortiums for more than 7 years. Speaking generally, he explained that the oil and gas industry is interested in nanoparticles partly because of the potential efficiencies they offer. It helps to think of nanoparticles from a chemical perspective; their collectively high-surface-area—typically where chemical reactions take place—means even relatively small volumes can make a big impact.
“The negatives include the fact that in many cases engineering these nanoparticles, or nanostructures, can be very costly,” said Rainey. “And while it may be easy to do on a small scale, learning how to scale something up to the oil field is going to take a lot of effort, and the ability to do that is sometimes unknown.”
That point about scale is very important, especially when discussing reservoir applications. Rainey emphasized that if large doses of nanoparticles are needed, then their cost must be relatively low to justify their use. He said the ability to strike such a balance will separate “laboratory curiosities” from viable commercial products.
Experimental and Numerical Studies of CO2 EOR in Unconventional Reservoirs
Authors: Wilson Adam 
Published: February 2017

This article, written by Special Publications Editor Adam Wilson, contains highlights of paper SPE 179634, “Experimental and Numerical Studies of CO2 EOR in Unconventional Liquid Reservoirs With Complex Fracture Networks,” by Jianlei Sun, SPE, Amy Zou, and David Schechter, SPE, Texas A&M University, prepared for the 2016 SPE Improved Oil Recovery Conference, Tulsa, 11–13 April. The paper has not been peer reviewed.
This study investigates oil-production mechanisms from the matrix into the fracture by simulating two laboratory experiments as well as several field-scale studies and evaluates the potential of using carbon dioxide (CO2) huff ’n’ puff to enhance oil recovery in unconventional liquid reservoirs (ULRs) with nanodarcy-range matrix permeability and complex natural-fracture networks. This study explores the mechanisms contributing to oil recovery with numerical modeling of experimental work and investigates the effects of various parameters on oil recovery.
Introduction
CO2 injection has been recognized as one of the more important and successfully applied enhanced-oil-recovery (EOR) processes in the US since the start of the first commercial CO2-injection project in 1972. Statistics show that, out of the 153 active CO2 EOR projects worldwide, 139 of them are in the US. CO2 flooding is the only EOR method in the US that has been consistent and economical since the drop in oil prices in the 1980s. One of the main advantages of CO2 injection is that CO2 can achieve miscibility with the resident hydrocarbon when minimum miscibility pressure (MMP) is attained.
Although CO2 flooding has demonstrated the potential of increasing oil production in conventional reservoirs, if this EOR process were to be applied to ULRs, the oil-recovery mechanism could not be considered the same as that during a conventional CO2 flooding because of the differences in reservoir petrophysical properties, fluid-phase behavior, and the fundamental mass-transfer mechanisms.
In general, diffusion during gas injection has been recognized as a critical mechanism that affects the oil recovery in fractured reservoirs. If the diffusive flow in the matrix is being neglected during simulation, the calculated result will underestimate productivity.
Furthermore, complex fracture geometry has been proposed for hydraulic fracturing because of the intersection between hydraulic fractures and in-situ natural fractures. Numerous simulation and experimental studies have evaluated production performance of complex fracture networks. However, there is no extensive work regarding the potential of CO2 huff ’n’ puff in complex fracture geometries.
Hip and Knee Osteoarthritis Affects Younger People, Too
Authors: Ackerman Ilana N. , Kemp Joanne L. , Crossley Kay M. , Culvenor Adam G. , Hinman Rana S. 
Published: February 2017

Synopsis Although osteoarthritis (OA) has traditionally been considered a disease of older age, hip and knee OA can and does affect younger adults, with a profound impact on psychosocial well-being and work capacity. Obesity and a history of traumatic knee injury (eg, anterior cruciate ligament rupture and/or meniscal tear) are key risk factors for the accelerated development of knee OA, while structural hip deformities (including those contributing to femoroacetabular impingement syndrome) are strong predictors of early-onset hip OA. In view of these associations, rising rates of obesity and sports injuries are concerning, and may signal a future surge in OA incidence among younger people. Assessment of hip and knee OA in younger people should focus on a patient-centered history, comprehensive physical examination, performance-based measures, and patient-reported outcome measures to enable monitoring of symptoms and function over time. Referral for imaging should be reserved for people presenting with atypical signs or symptoms that may indicate diagnoses other than OA. Nonpharmacological approaches are core strategies for the management of hip and knee OA in younger people, and these include appropriate disease-related education, activity modification (including for work-related tasks), physical therapist- prescribed exercise programs to address identified physical impairments, and weight control or weight loss. High-quality evidence has shown no benefit of arthroscopy for knee OA, and there are no published clinical trials to support the use of hip arthroscopy for OA. Referral for joint-conserving or joint replacement surgery should be considered when nonpharmacological and pharmacological management strategies are no longer effective. J Orthop Sports Phys Ther 2017;47(2):67–79. doi:10.2519/jospt.2017.7286
Le non-recours à la mobilité internationale chez les jeunes avec moins d’opportunités
Authors: Labadie Francine , Talleu Clotilde 
Published: February 2017

Si permettre à de jeunes avec moins d’opportunités d’accéder à la mobilité internationale hors de l’école est un objectif politique important au niveau européen et national, il ne semble pas encore atteint en France. Prenant appui sur une étude qualitative conduite par l’INJEP, cet article montre l’existence de freins – provenant de représentations, normes ou mécanismes institutionnels – présents dans les structures de l’insertion sociale et professionnelle, prescriptrices de première ligne de la mobilité de ces jeunes. Ces obstacles peuvent aboutir à des cas de « non-recours » par « non-proposition », ce qui est particulièrement regrettable au regard des significations que les jeunes accordent à ce type d’expérience : une opportunité de se construire en tant qu’êtres autonomes, libres de faire leurs propres choix et de décider de l’orientation de leur parcours.
Blogging as an Innovative Method of Peer-to-Peer Educational Sharing
Authors: Nedder Melanie M. , Levine Sharon A. , Galligan Caroline , Avery Kathleen Ryan , Eagan-Bengston Elizabeth , Reilly Karen M. 
Published: February 2017

BACKGROUND
Nurses in the cardiac intensive care unit often attend professional education opportunities. However, it is difficult to share this information among nursing staff. Varying schedules, different shifts, and patient acuity limit the amount of time available for peer-to-peer sharing of educational information. A review of the literature revealed scant research on blogging for peer-to-peer education in general and particularly in nursing.

OBJECTIVES
To explore nurses’ perception of the effectiveness of using a blog as a forum to provide peer-to-peer sharing of relevant professional education.

METHODS
Using a simple, free blogging website, the unit’s nursing practice council developed a private blog for educational information sharing among the nursing staff. An online survey was administered to the unit’s staff 15 months after the blog was implemented.

RESULTS
Most respondents indicated that they thought the blog is an effective way to share professional education (86%), keeps them abreast of evidence-based practice (81%), and has led to practice change (59%). Nearly 80% of respondents agreed that they are more likely to attend professional conferences, and 62% would consider contributing blog posts.

CONCLUSION
The survey results suggest that blogging may be an effective method of peer-to-peer sharing of education, although more rigorous research is required in this area.
Electronic Sentinel Surveillance of Influenza-like Illness
Authors: Adnan Mehnaz , Peterkin Donald , Lopez Liza , Mackereth Graham 
Published: February 2017

SummaryBackground: Electronic reporting of Influenza-like illness (eILI) from primary care was implemented and evaluated in three general medical practices in New Zealand during May to September 2015.Objective: To measure the uptake of eILI and to identify the system’s strength and limitations. Methods: Analysis of transactional data from the eILI system; comparative study of influenza-like illness cases reported using manual methods and eILI; questionnaire administered to clinical and operational stakeholders.Results: Over the study period 66% of total ILI cases were reported using eILI. Reporting timeliness improved significantly compared to manual reporting with an average of 24 minutes from submission by the clinician to processing in the national database. Users found the system to be user-friendly.Conclusion: eILI assists clinicians to report ILI cases to public health authorities within a stipulated time period and is associated with faster, more reliable and improved information transfer.