bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fra Israels til palestinernes beste venn?
Authors: Waage Hilde Henriksen 
Published: September 2024

Etter 1948 var Norge en av Israels aller beste venner. Palestinernes skjebne vakte ingen interesse. De var glemt. Etter krigen i 1967 forandret disse holdningene seg. Israel var blitt en okkupasjonsmakt. Det palestinske flyktningproblemet var like uløst. PLO hadde også endret politikk, var blitt langt mer kompromissvillig og gikk inn for en tostatsløsning. Like fullt hadde Norge den mest restriktive politikken overfor PLO i hele Vest-Europa. Først i 1986 fikk PLO et informasjonskontor i Norge. I 1989 kom Norges første offisielle besøk til PLO i Tunis. Gjennom hele 1980-tallet var Arbeiderpartiet pådriveren for den nye norske politikken. Den var bygd på det nye tillitsforholdet til PLO og det nære forholdet til Israel. I 1993 forhandlet Norge fram Oslo-avtalen. Norges nære forhold til Israel hadde gjort Norge akseptabel. PLO skjønte også at det trengte en Israel-venn. Men i Norge var det ikke lenger noen sterk sympati for Israel. Det var den norske rollen som gjorde at Norge ikke kunne føre noen demonstrasjonspolitikk og markere standpunkter som Israel fant uakseptable. Først under Gazakrigen i 2023 har Norge hatt en ny pådriverrolle, også internasjonalt, for å få slutt på krigen og få i gang forhandlinger om en tostatsløsning.
Abstract in English:From Israel’s to the Palestinians’ Best Friend?After 1948, Norway became one of Israel’s closest friends. The fate of the Palestinians did not arouse any interest. After the war in 1967, these attitudes changed. Israel had become an occupying power. The Palestinian refugee problem remained unresolved. The PLO had also changed its policy and advocated for a two-state solution. Nevertheless, Norway had the most restrictive policy towards the PLO in all of Western Europe. It was not until 1986 that the PLO received an information office in Norway. In 1989, Norway made its first official visit to the PLO in Tunis. Throughout the 1980s, the Labour Party was the driving force behind the new Norwegian policy. It was built on the new trust relationship with the PLO and the close relationship with Israel. In 1993, Norway negotiated the Oslo Accords. Norway’s close relationship with Israel had made it possible. The PLO also realized that it needed a friend of Israel. However, there was no longer strong sympathy for Israel in Norway. Norway’s role forced Norway to pursue a policy acceptable for Israel. Only during the Gaza War in 2023 has Norway been at the forefront internationally in efforts to end the war and initiate negotiations for a two-state solution.
EFIKASI KONSORSIUM Bacillus sp. DAN Pseudomonas fluorescens TERHADAP LAYU FUSARIUM PADA TANAMAN CABAI RAWIT (Capsicum frutescens L.)
Authors: Agustina Nensi , Purnawati Arika , Prasetyawati Endang Triwahyu , Lestari Safira Rizka 
Published: September 2024

Fusarium oxysporum f.sp. capsici merupakan patogen penting pada cabai rawit karena menyebabkan penyakit layu, merugikan dan menurunkan produksi hingga 50%. Pengendalian secara kimiawi menggunakan fungisida telah banyak dilakukan namun berdampak negatif terhadap lingkungan. Berdasarkan percobaan di lapangan, aplikasi konsorsium bakteri Bacillus sp. dan Pseudomonas fluorescens dapat mengendalikan penyakit layu Fusarium. Tujuan dari penelitian ini adalah untuk mengetahui tingkat efikasi dan pengaruh aplikasi konsorsium Bacillus sp. dan Pseudomonas fluorescens terhadap penyakit layu yang disebabkan oleh F. oxysporum f.sp. capsici. Penelitian ini dilakukan dengan menginokulasi 100 ml F. oxysporum f.sp. capsici (104 spora ml-1) dan 25 ml konsorsium bakteri (109 CFU mL-1), lalu diamati tingkat efikasi dan pengaruhnya terhadap perkembangan penyakit layu Fusarium. Rancangan penelitian ini adalah Rancangan Acak Lengkap (RAL) yang terdiri dari dua faktor yaitu konsorsium Bacillus sp. (Ba9) dengan Pseudomonas fluorescens, konsorsium Bacillus sp. (Ba17) dengan Pseudomonas fluorescens, ulangan sebanyak tiga kali dan analisis data menggunakan uji Tukey's HSD. Hasil penelitian bahwa konsorsium bakteri dapat menurunkan intensitas penyakit rata-rata 45-66%.
RESPON PERKECAMBAHAN BENIH SORGUM (Sorghum bicholor [L.]Moench)TERHADAP PRIMING DENGAN LARUTAN POLYETHYLENE GLYCOL-6000
Authors: Sakti Alfiana Revo , Pramono Eko , Agustiansyah Agustiansyah , Kamal Muhammad Ratih 
Published: September 2024

Ketersediaan benih sorgum yang bermutu menjadi salah satu pendukung bagi budidaya tanaman. Benih yang mengalami kemunduran akibat lamanya periode penyimpanan perlu diperbaiki dengan menerapkan perlakuan priming. Tujuan penelitian adalah untuk mengetahui respon perkecambahan benih sorgum, Numbu dan UPCA-S1, yang telah disimpan 35 bulan dalam ruang simpan bersuhu ±18ºC terhadap perlakuan priming dengan konsentrasi bertaraf Polyethylene glycol (PEG-6000). Penelitian ini dilaksanakan di Laboratorium Benih dan Pemuliaan Tanaman Fakultas Pertanian Universitas Lampung dari bulan April sampai dengan Mei 2021. Percobaan priming yang menggunakan PEG-6000 dengan konsentrasi meningkat 0, 5, 10, 15, dan 20% ini diterapkan pada benih sorgum Numbu dan UPCA-S1. Lama perendaman benih dalam larutan PEG-6000 adalah 24 jam. Percobaan ini menggunakan faktor tunggal PEG-6000 dengan lima taraf konsentrasi dengan dua ulangan. Respon perkecambahan benih sorgum terhadap konsentrasi PEG-6000 yang meningkat dilihat dengan regresi menggunakan perangkat lunak pengolah data Minitab-17. Hasil menunjukkan bahwa respon perkecambahan benih terhadap konsentrasi PEG-6000 yang meningkat adalah kuadratik. Daya berkecambah benih sorgum Numbu dan UPCA-S1 mencapai maksimum 88% dan 98% yang masing-masing dicapai pada konsentrasi PEG-6000 9% dan 16%.
PENGARUH SISTEM OLAH TANAH DAN PEMUPUKAN NITROGEN JANGKA PANJANG TERHADAP DISTRIBUSI AGREGAT TANAH DALAM PERTANAMAN KACANG HIJAU (Vigna radiata L.) PADA TANAH ULTISOL
Authors: Subandi Ricky Dwi , Afandi Afandi , Afrianti Nur Afni , Banuwa Irwan Sukri 
Published: September 2024

Penelitian ini bertujuan untuk mengetahui pengaruh sistem olah tanah terhadap distribusi agregat tanah, pengaruh pemupukan nitrogen terhadap distribusi agregat tanah, dan interaksi keduanya terhadap distribusi agregat tanah. Penelitian ini menggunakan rancangan acak kelompok (RAK) disusun secara faktorial dengan 2 faktor dan 4 ulangan. Faktor pertama yaitu sistem olah tanah yang meliputi olah tanah intensif (T1), olah tanah minimum (T2) dan tanpa olah tanah (T3). Faktor kedua yaitu pemupukan nitrogen dosis urea 0 kg ha-1 (N0) dan 50 kg dosis urea ha-1 (N2). Variabel pengamatan meliputi persentase distribusi agregat, C- organik, dan data produksi kacang hijau. Hasil penelitian menunjukkan bahwa persentase distribusi agregat tertinggi terdapat pada perlakuan tanpa olah tanah (T3) dan produksi kacang hijau tertinggi pada perlakuan pemupukan nitrogen dosis nrea 50 kg ha-1 (N2). Tidak terdapat interaksi antara sistem olah tanah dan pemupukan nitrogen terhadap C- organik serta distribusi agregat tanah.
Growth Dynamics and Density of Pine Wood after Resin Harvesting in the Lingonberry Forest Type in the Leningrad region
Authors: Штрахов С.Н. , Данилов Д.А. , Зайцев Д.А. 
Published: September 2024

В статье рассмотрено восстановление ширины годичного слоя и формирование базисной плотности древесины сосны обыкновенной в насаждении, пройденном подсочкой. По образцам древесины определяли её базисную плотность и изучали динамику радиального прироста с его последующей индексацией. Полученные количественные данные обрабатывали методами вариационной статистики. Установлено влияние ширины зоны поздней ксилемы на плотность древесины, показано снижение вариации показателей прироста за 40-летний период после подсочки по сравнению с 20-летним периодом. У наиболее крупных деревьев после подсочки прирост относительно модельных значений кривой хода роста восстановился быстрее, чем у деревьев более мелких ступеней толщины.
The article considers the recovery of annual growth width after resin harvesting and the formation of basic wood density of a plantation of common pine passed by felling. Its basic density was determined for the samples of wood and the dynamics of wood growth was studied with its indexation. The obtained quantitative data were processed by methods of variation statistics. The influence of the width of the late xylem zone on wood density was established, and a decrease in the variation of growth indices for the period of 40 years after resin harvesting relative to the period of 20 years was shown. For the largest tree thickness classes, growth relative to model values of the growth progress curve recovered faster after resin harvesting than for trees of smaller thickness stages.
Using Fractal Methods to Assess Soil Structure after the Creation of Firebreaks
Authors: Цветков И.В. , Кульнев В.В. , Кумани М.В. , Насонов А.Н. , Абду­жаб­баров Х.М. , Трегубов О.В. , Похваленко В.А. , Ухтомский В.Г. 
Published: September 2024

Представлена новая методика оценки качества механической обработки почв и подстилающих пород, основанная на измерении фрактальных характеристик изображений их срезов. Методику предлагается использовать для повышения эффективности механической обработки субстрата при организации противопожарных минерализованных полос. При этом обосновывается применение фрактальных методов для оценки изменения структуры субстрата, возникающего вследствие внешнего воздействия, которое в данном случае осуществляется плужным каналокопателем при различных углах наклона режущей пластины и скоростях его перемещения в толще грунта. Планирование эксперимента и обработка его результатов проводились на основе предположения о том, что как почвы, так и грунты зоны аэрации представляют собой неоднородную диссипативную систему с самоорганизованной критичностью состояний, которые закономерно изменяются в процессе внешнего воздействия на субстрат. При этом наблюдается эффект самоорганизованной критичности диссипативной системы, отличительным признаком которого является проявление самоподобия составляющих ее элементов. То есть в основе описываемого метода лежит изучение масштабной инвариантности структурных элементов грунта в процессе внешнего механического воздействия. На основе предложенной методики разработаны оптимальные режимы работы специального оборудования и механизмов для среднесуглинистых тёмно-серых лесных почв.
This paper presents a new method for assessing the quality of mechanical processing of soils and underlying rocks based on measuring the fractal characteristics of their section images. The method is proposed to be used to improve the efficiency of mechanical processing of the substrate when organizing fire-prevention mineralized strips. At the same time, the use of fractal methods is substantiated for assessing changes in the structure of the substrate arising from external action, which, in this case, is carried out by a plow channel digger at different angles of inclination of the cutting plate and speeds of its movement in the soil thickness. The experiment was planned and its results were processed based on the assumption that both soils and aeration zone soils are a heterogeneous dissipative system with self-organized criticality of states that change regularly during external action on the substrate. In this case, the effect of self-organized criticality of the dissipative system is observed, the distinctive feature of which is the manifestation (self-similarity) of its constituent elements. That is, the described method is based on the study of the scale invariance of soil structural elements during external mechanical action. Based on the proposed methodology, optimal operating modes of special equipment and mechanisms for medium-loamy dark-gray forest soils have been developed.
Trifarotene alleviates skin photoaging injury by inhibition of JNK/c-Jun/MMPs
Authors: Fei Xuan , Yang Lele Zixin , Zhang Jingjing , Li Xiang , Pan Mengtian , Xu Guangchen , Zhang Cuixia , Liu Fei , Fang Weirong 
Published: September 2024

Abstract
Long-term exposure to ultraviolet (UV) radiation induces skin photoaging, which manifests as oxidative stress, inflammation, and collagen degradation. Multiple approaches (topical or systemic retinoids, antioxidants, alpha-hydroxy acids, laser, surgery) are used in the treatment of photoaged skin, and the use of topical retinoids is currently a primary clinical treatment. Previous studies revealed that retinoic acid promotes keratinocyte proliferation and reduces melanin deposition and matrix metalloproteinase (MMP) secretion; it also causes potential allergic and inflammatory damage to the skin. This study aimed to investigate the therapeutic effects and mechanisms of trifarotene, a functional retinoic acid analog, on UV-irradiated photoaging ICR and BALB/c nude mice and UVB photodamaged human epidermal keratinocyte (HaCaT) cells by examining indicators such as collagen, oxidoreductase, and inflammatory factor presence through histochemical staining, Western blot, and ELISA. Results suggested that trifarotene significantly reduced UV-induced photoaging in mouse skin tissue, potentially by reducing oxidative stress damage and inflammatory factor release, and inhibiting melanin deposition and collagen degradation by downregulating MMP expression. Concentrations of malondialdehyde, tyrosinase, interleukin-6, interleukin- 12, and tumor necrosis factor-alpha in photoaged skin decreased, while SOD content in photodamaged HaCaT cells significantly increased. Trifarotene (3.3 μmol L–1) inhibited phosphorylated JNK and c-Jun expression both independently and collaboratively with the JNK activator anisomycin, demonstrating that trifarotene mitigates UV-induced collagen degradation and apoptosis through inhibition of the JNK/c-Jun/MMPs signaling pathway.
Analysis of doxorubicin and fullerenol in rat serum by micellar electrokinetic capillary chromatography
Authors: Injac Rade , Sertić Miranda , Glavač Nina Kočevar 
Published: September 2024

Abstract
A new micellar electrokinetic capillary chromatographic (MEKC) method has been developed and optimized for simultaneous quantitation of doxorubicin (Dox) and fullerenol (Frl) in rat serum. The separation was carried out in a capillary (48.5–40 cm to the detector – 50 µm id fused-silica capillary with bubble cell, 150 µm) at an applied voltage of 25 kV and temperature of 25 °C. For the background electrolyte 10 mmol L–
1 borate buffer pH 9.3 plus 15 mmol L–1 phosphate buffer pH 7.0 (with the final pH of the mixture adjusted to 7.0 with HCl), with added 10 % (V/V) methanol, and 15 mmol L–1 sodium dodecyl sulfate as a surfactant, were used. The hydrodynamic injection was carried out at 5.0 kPa during the period of 100 s. Linear calibration curves were established over the concentration range 0.5–500.0 mg L–
1 for Dox and 10.0–500.0 mg L–
1 for Frl (at 234 nm). The proposed MEKC procedure was fully validated and applied for the deter mination of Dox and Frl in Wistar rats after intra pe ritoneal administration of both molecules.
Exploring novel pharmacological trends: Natural compounds in dry eye disease management
Authors: Rák Tibor , Csutak Adrienne 
Published: September 2024

Abstract
Dry eye disease (DED) is an ocular condition characterized by altered tear film homeostasis, resulting in symptoms like tear film instability, hyperosmolarity, inflammation, and neurosensory abnormalities. It affects visual acuity and quality of life and is influenced by age, gender, and environmental factors. The first line of treatment consists of dynamically developing artificial tears, gels, and eyelid sprays, which can be supplemented with natural ingredients for enhanced efficacy. Other therapeutic steps include auto-logous serum tears, anti-inflammatory and immunosuppressive eyedrops, or oral tablets. Management also targets Meibomian gland dysfunction and the ocular surface micro-biome. This article explores various therapeutic approaches, including natural compounds and complementary strategies. Natural compounds, such as vitamins, and herbal substances (e.g., trehalose), offer promising benefits in enhancing tear film stability and ocular surface protection. Apitherapeutic products like manuka honey and propolis exhibit antibacterial and anti-inflammatory properties. Additionally, human tissue-derived solutions, such as auto-logous serum tears and amniotic membrane extracts, hold the potential for ocular surface regeneration. Other strategies, including polyherbal eye drops, liposomal eyelid sprays, and microbiome-supporting solutions offer alternative therapeutic avenues. Moreover, patient education, lifestyle modifications, and interdisciplinary collaboration play crucial roles in DED management, emphasizing the importance of holistic care approaches.
Personalization of thiopurine therapy: Current recommendations and future perspectives
Authors: Urbančič Dunja , Pasha Flaka , Šmid Alenka , Mlinarič-Raščan Irena 
Published: September 2024

Abstract
Despite great therapeutic advances in the field of biologics, small synthetic molecules such as thiopurines, including azathioprine, mercaptopurine, and thioguanine, remain an important therapeutic pillar in the treatment of inflammatory bowel disease, other autoimmune disorders, and cancer. This review presents the latest guidelines for thiopurine administration, highlighting the importance of individualized therapy guided by pharmacogenomics. It emphasizes dose adjustment based on nudix hydrolase 15 (NUDT15) and thiopurine S-methyltransferase (TPMT) genotype, along side thiopurine S-methyltransferase activity and thiopurine metabolic profile. In addition, the article takes a critical look at emerging research in the field of thiopurine pharmaco genomics featuring novel genetic markers and technological developments in genetic testing. Finally, the potential of integrated approaches that combine genetic, meta bolic, and clinical factors to further individualize thiopurine therapy is highlighted.
Optimizing High-Performance Concrete Properties Containing Blast Furnace Slag and Marble Powder
Authors: Edeb Belkacem , Allout Naas , Benkhelil Mahmoud , Guettala Salim 
Published: September 2024

Abstract
Building and industrialization-related environmental harm is becoming an increasingly serious concern. In an effort to create an eco-friendly high-performance concrete (HPC), this paper addresses the idea of partially replacing cement with recyclable industrial waste. The current study will experimentally examine the slump, the strengths of compressive (SC) and porosity (P) of fifteen HPC mixtures manufactured from locally available resources. Hence, the effects of utilizing marble powder (MP) as a mineral additive in binary mixes and ternary with cement (PC) and granulated ground blast furnace slag (GGBFS) on the HPCs properties were studied in order to develop statistical models based on mixture design. Highly accurate prediction graphs and models were created for HPC workability, P at 28-day, SC at 7 and 28-day. All responses have satisfactory coefficients of correlation (R2 ≥ 0.76). Replacing cement with GGBFS causes a rise in slump in mixtures. Nevertheless, that only remains relevant when the mixtures have a small MP percentage (≤ 25%). A minor decrease in SC can be attributed by an increase of GGBFS. After 28-day, using GGBFS alone caused a little drop in SC; however, when GGBFS and PC were mixed, SC increased, in comparison with reference composition, and the porosity was reduced. Conversely, SC is superior with lower porosity when a small amount of MP is utilized. The best combination is HPC14, containing 5% GGBFS; it offers an optimal equilibrium among the three qualities; with HPC4’s (15%GGBFS+5%MP) qualities, being almost identical to those of reference HPC15, a lower amount of cement may also be utilized. Findings encourage the use of MP and GGBFS to partially replace cement to produce eco-friendly and cost-effective HPC. An extremely high correlation coefficient indicated a strong relationship between P and SC.
Research on the Application of Computer Vision Technology and Optimization of Space Design in a Smart Home Environment
Authors: Peng Mengzhou , Kang Xiaoran , Zhang Xun , Zhao Chenxu 
Published: September 2024

Abstract
This study aims to explore the application of computer vision technology in smart home environments and its influence on space design optimization. Through the comprehensive application of image recognition and processing technology, the behavior patterns of family members, the placement status of household items, and the real-time changes in the indoor environment in smart home systems are deeply analyzed. The experimental results show that computer vision technology can effectively improve smart home systems’ perception and analysis ability, providing data support for automatically adjusting indoor environments and providing personalized service. At the same time, this study also focuses on the optimization strategy of space design based on computer vision technology and puts forward a series of humanized design schemes through reasonable arrangement of cameras and sensors, real-time analysis of user behavior data and environmental parameters, aiming at improving living comfort and achieving efficient use of energy. This study reveals the internal relationship between computer vision technology and space design, which complement each other and jointly promote the intelligent and humanized development of smart homes.
Numerical modeling and fatigue analysis of the dynamic response of main pump cable in nuclear power plant
Authors: Jingqi Wang , Lixia Guo , Wei Liu , Yadong Wang , Dongfang Wu , Zimeng Chen 
Published: September 2024

Abstract
The structural temperature rise and thermal stress caused by operation current and ambient temperature are some of the main factors affecting cable fatigue life. Combined with the operating and environmental conditions of the main cooling pump of the nuclear power plant, the thermal-structural coupling field numerical modeling and fatigue analysis of the 6kV single-core and three-core cable of the main pump is carried out. Based on obtaining the steady-state operating current, the motor start-up transient current, and the circulating ambient temperature, the thermal-structural coupling field numerical model of the main pump cable is established using the load transfer method to obtain the thermal and stress field distribution of the internal structural layer. The load history of one cycle is extracted for the fatigue numerical simulation of the main pump cable. The stress time history of the cable structure layer was constructed by the stress calculation results and the load time history of a single period, and the fatigue life of the main pump cable was obtained based on the S-N curve of the main insulation material and the Miner’s linear cumulative damage theory. The simulation results show that the force acting on the main pump cable by the operating current and ambient temperature is an approximately symmetric cyclic load of constant amplitude. The life cycle of the cable can reach 2.235*e4 times, and the overall life of the cable is about 63.97 years. This study can provide theoretical guidance for the safety and reliability design and state operation and maintenance of the main pump cable of the nuclear power plant.