bluuebunny/crossref_metadata_2025_split huggingface dataset:
Membership robustness but structural change of the native gut microbiota of bumble bees upon systemic immune induction
Authors: Sauers Logan A. , Bassingthwaite Toby , Sierra-Rivera Bryan , Hampton Kylie J. , Duffield Kristin R. , Gore Haley , Ramirez José L. , Sadd Ben M. 
Published: October 2024

ABSTRACT

Understanding factors influencing the composition and maintenance of beneficial host-associated microbial communities is central to understanding their ecological, evolutionary, and health consequences for hosts. Host immunity is often implicated as a regulator of these microbiota, but immunity may also play a disruptive role, with responses to infection perturbing beneficial communities. Such effects may be more prominent from innate immune responses, with more rapid-acting and often non-specific components, compared to adaptive responses. We investigated how upregulation of antibacterial immunity in the bumble bee
Bombus impatiens
affects its core gut microbiota, testing the hypothesis that immunity-induced perturbation impacts the microbiota structure. Freshly emerged adult bees were fed a microbiota inoculum before receiving a non-pathogenic immune stimulation injection. We quantified microbial communities using 16S rRNA amplicon sequencing and targeted quantitative PCR. Coarse community membership shows apparent robustness, but we find that immune stimulation alters the abundance of two core community members,
Gilliamella
and
Snodgrassella
. Moreover, a positive association in communities between these bacteria is perturbed following a Gram-negative challenge. The observed changes in the gut microbial community are suggestive of immune response-induced dysbiosis, linking ecological interactions across levels between hosts, their pathogens, and their beneficial gut microbiota. The potential for collateral perturbation of the natural gut microbiota following an innate immune response may contribute to immune costs, shaping the evolutionary optimization of immune investment depending on the ecological context.

IMPORTANCE
Our work demonstrates how innate immunity may influence the host-associated microbiota. While previous work has demonstrated the role of adaptive immunity in regulating the microbiota, we show that stimulation of an innate immune response in bumble bees may disrupt the native gut microbial community by shifting individual abundances of some members and pairwise associations. This work builds upon previous work in bumble bees demonstrating factors determining microbe colonization of hosts and microbiota membership, implicating immune response-induced changes as a factor shaping these important gut communities. While some microbiota members appear unaffected, changes in others and the community overall suggests that collateral perturbation of the native gut microbiota upon an innate immune response may serve as an additional selective pressure that shapes the evolution of host innate immunity.
DoubleTES detectors to investigate the CRESST low energy background: results from above-ground prototypes
Authors: Angloher G. , Banik S. , Benato G. , Bento A. , Bertolini A. , Breier R. , Bucci C. , Burkhart J. , Canonica L. , D’Addabbo A. , Lorenzo S. Di , Einfalt L. , Erb A. , Feilitzsch F. v. , Fichtinger S. , Fuchs D. , Garai A. , Ghete V. M. , Gorla P. , Guillaumon P. V. , Gupta S. , Hauff D. , Ješkovský M. , Jochum J. , Kaznacheeva M. , Kinast A. , Kluck H. , Kraus H. , Kuckuk S. , Langenkämper A. , Mancuso M. , Marini L. , Mauri B. , Meyer L. , Mokina V. , Olmi M. , Ortmann T. , Pagliarone C. , Pattavina L. , Petricca F. , Potzel W. , Povinec P. , Pröbst F. , Pucci F. , Reindl F. , Rothe J. , Schäffner K. , Schieck J. , Schönert S. , Schwertner C. , Stahlberg M. , Stodolsky L. , Strandhagen C. , Strauss R. , Usherov I. , Wagner F. , Wagner V. , Zema V. ,   CRESST Collaboration
Published: October 2024

AbstractIn recent times, the sensitivity of low-mass direct dark matter searches has been limited by unknown low energy backgrounds close to the energy threshold of the experiments known as the low energy excess (LEE). The CRESST experiment utilises advanced cryogenic detectors constructed with different types of crystals equipped with Transition Edge Sensors (TESs) to measure signals of nuclear recoils induced by the scattering of dark matter particles in the detector. In CRESST, this low energy background manifests itself as a steeply rising population of events below 200 eV. A novel detector design named doubleTES using two identical TESs on the target crystal was studied to investigate the hypothesis that the events are sensor-related. We present the first results from two such modules, demonstrating their ability to differentiate between events originating from the crystal’s bulk and those occurring in the sensor or in its close proximity.
Unsupervised detection of coordinated fake-follower campaigns on social media
Authors: Zouzou Yasser , Varol Onur 
Published: October 2024

AbstractAutomated social media accounts, known as bots, are increasingly recognized as key tools for manipulative online activities. These activities can stem from coordination among several accounts and these automated campaigns can manipulate social network structure by following other accounts, amplifying their content, and posting messages to spam online discourse. In this study, we present a novel unsupervised detection method designed to target a specific category of malicious accounts designed to manipulate user metrics such as online popularity. Our framework identifies anomalous following patterns among all the followers of a social media account. Through the analysis of a large number of accounts on the Twitter platform (rebranded as X after the acquisition of Elon Musk), we demonstrated that irregular following patterns are prevalent and are indicative of automated fake accounts. Notably, we found that these detected groups of anomalous followers exhibited consistent behavior across multiple accounts. This observation, combined with the computational efficiency of our proposed approach, makes it a valuable tool for investigating large-scale coordinated manipulation campaigns on social media platforms.
Synthesis of porphyrin triads chelated with thallium(III) for studies of ground-state hole/electron transfer
Authors: Wang Jieqi , Taniguchi Masahiko , Bocian David F. , Lindsey Jonathan S. 
Published: October 2024

Four target all-porphyrin triads have been prepared for fundamental studies of ground-state hole/electron transfer. Each triad contains thallium(III) porphyrins as bookends, which bear mesityl groups at the three non-linking meso-positions. The central porphyrin is a free base or thallium(III) porphyrin bearing mesityl or pentafluorophenyl groups at the two non-linking meso-positions. The linker is a 4,4′-diphenylethyne unit joined at the porphyrin meso-positions. The net spacer between the two bookend thallium(III) porphyrins thus consists of diphenylethyne–porphyrin–diphenylethyne and is designed as a superexchange element for through-bond hole/electron transfer. The energetics of the superexchange element are tunable given the nature of the substituents and metalation state of the central porphyrin. The synthesis entailed Sonogashira coupling of two building blocks, a free base bis(4-iodophenyl)porphyrin and a mono-ethynylporphinato thallium(III) chloride. Two benchmark porphyrins also were prepared. Absorption spectral comparisons are provided including of the all-thallium(III) monomer, dimer, and triad.
Maternal Satisfaction With Children’s Vaccination and Its Contributing Factors in Ethiopia: A Systematic Review and Meta‐Analysis
Authors: Assimamaw Nega Tezera , Endalamaw Aklilu , Kelkay Mengistu Makonnen , Gonete Almaz Tefera , Terefe Bewuketu , Zeleke Kassaye Ahmed 
Published: October 2024

Background: Various initiatives are underway to improve maternal satisfaction with the vaccination of children in developing nations. Governments, international organizations, and nongovernmental organizations are actively working to improve healthcare infrastructure, expand service accessibility, improve communication, and foster community engagement. However, despite these efforts, maternal satisfaction with child vaccination services continues to be a significant issue.Objective: This systematic review and meta‐analysis is aimed at assessing the pooled prevalence of maternal satisfaction with the child’s vaccination service and its predictors in Ethiopia.Methods: Scopus, Embase, Web of Science, Google Scholar, PubMed, African Journals Online, and Semantic Scholar were searched to access the included articles. A weighted inverse‐variance random effect model was used to estimate the prevalence of maternal satisfaction with vaccination of children. Variations in pooled prevalence estimates were adjusted by subgroup analysis according to the specific region where the study was conducted. Funnel plot and Egger’s regression test were used to check publication bias. STATA version 14 statistical software was used for meta‐analysis.Results: The combined prevalence of maternal satisfaction with vaccination of children was found to be 73% (95% CI: 72–75; I2 = 0.00%, p value < 0.001). Based on the subgroup analysis, the result revealed that the prevalence of maternal satisfaction with vaccination of children was 63% in SNNPR, 79% in Oromia, and 74% in Amhara.Conclusions: A meta‐analysis of mothers’ satisfaction with vaccination services for their children in Ethiopia found a low level of satisfaction. Therefore, provide regular training and capacity‐building programs for healthcare workers involved in the delivery of vaccination services.
The Nexus Between Medical Care Policy Alienation and Career Success: A Cross‐Sectional Study
Authors: Xu Jia , Xia Chun , Zhu Hui , Ding Xiuzhen 
Published: October 2024

Aim: This study examines the interrelationship between medical staff’s sense of medical care policy alienation (SPA) and their subjective career success and the potential mediating roles of occupational calling (OC) and job satisfaction.Background: Medical staff’s pivotal role in medical care policy implementation outcomes underscores their approach to career success, which affects work efficiency, and willingness to implement medical care policy. Effective policy is anticipated to be positively and rationally implemented, fostering favorable perceptions and career success among policy executors such as medical staff. However, limited research examines the relationship between career outcomes and medical staff′s SPA.Methods: A cross‐sectional study conducted from May to June 2023 collected data from 521 medical staff in 14 hospitals in northern, western, and southern China through questionnaire surveys. The questionnaire measured their SPA, OC, job satisfaction, and career success. A chain multiple mediation model was constructed to explore SPA’s relationship with medical staff’s OC and job satisfaction, resulting in less career success, and whether work overload moderated this relationship.Results: Medical staff’s SPA was negatively related to career success via a chain mediation mechanism involving OC and job satisfaction. Work overload did not moderate SPA’s negative association with OC; however, it moderated its association with job satisfaction. High workload intensified SPA’s association with job satisfaction, increasing the mediating effect on career success compared to those with lower workloads.Conclusion: Medical staff’s SPA was significantly negatively related to career success, reflected in a weakened OC, and decreased job satisfaction. Work overload somewhat moderated the relationship between SPA and job satisfaction. Policymakers and medical stakeholders should emphasize improved communication between medical institutions and staff, which is essential for crafting and disseminating medical care policies. Medical care policy implementation should be enhanced in diverse Chinese contexts to enrich the understanding of medical policy management.
Natural Law, Free Choice, and Moral Responsibility in the Anthropology of John Chrysostom
Authors: Stenger Jan R. 
Published: October 2024

Abstract
In his discussion of virtue and sin, John Chrysostom makes frequent reference to the law of nature. He defines it as a moral norm given by God at the time of creation and argues that on account of it humans know what must be done and what must not be done. This article examines the role of natural law in Chrysostom’s conception of human action, focusing on the relationship between the law and human freedom. It argues that Chrysostom draws on the philosophical idea of natural law in order to explain human moral responsibility and the capacity for good deeds. By clarifying the interplay between natural law and free choice he rejects the doctrine of determinism. It is shown that the concept of natural law is also fundamental for Chrysostom’s instruction as it provides a basis for the moral reformation of the believers’ actions and behaviour.
Making Memories: Countercultural Memory in Irenaeus, Martyrdom of Polycarp, and Apocryphon of James
Authors: Abbott Philip 
Published: October 2024

Abstract
Cultures define themselves largely by how they remember the past; the commemoration of history provides a link to bygone eras that helps determine social dynamics in the present. But not everyone remembers the past in the same manner. Not only do people champion competing historical narratives, but they also memorialize the past in different ways, such as erecting monuments, glorifying a specific person, constructing and honoring an archive, revering a symbol, holding an event that repeats periodically, maintaining an institution, and more. These various hubs of memory creation and preservation are often called “sites of memory.” This article explores how various Christian groups in the second century invested their social memory in divergent sites. These sites not only propagated differing forms of Christian expression, but also diverse notions of what it means to remember. While some championed preservation of the past, others believed that memory entailed radical innovation.
An Early Ofan for Hanukkah, the Temple Menorah, and the Visual Culture of Late Antique Synagogues
Authors: Lieber Laura Suzanne 
Published: October 2024

Abstract
This contribution focuses on an anonymous poem for Hanukkah and its wealth of visual imagery as a window on the interrelationship between liturgical texts and the art of the ancient synagogue. It sets this poem in conversation with the image of the menorah in synagogues excavated in the Land of Israel, as both reflect Jewish liturgical creativity during late antiquity, between the fourth and seventh or eighth centuries. It explores how the visual culture of Jewish late antiquity provided an early medieval payyetan (synagogue poet) with a rich library of objects, symbols, and metaphors for a composition celebrating the Festival of Lights; the poetic synthesis, in turn, yields a richly resonant symbolic matrix of meaning. Attention to light sources (lamps) and the symbolism of light more generally reveals how the material and visual culture of antiquity – particularly the menorah – suffused the piyyut, and how the piyyut could have colored perceptions of familiar experiences and objects. After examining lamps (and particularly menorahs) from a variety of perspectives, we will return to the poem to consider more closely the role that illumination plays in the short, festive lyric.
A Short Note on Agricultural Household’s Farm Income: Evidence from the National Sample Survey 77th Round
Authors: Shukla Vachaspati 
Published: October 2024

An examination of monthly farm income obtained by agricultural households in India presents a very dismal picture of these households. Only a small percentage of agricultural households in India receive a monthly farm income greater than ₹10,000. Furthermore, nearly 70 per cent of agricultural households in India earn a farm income of less than ₹5,000 per month. Agricultural households in several states are too poor even after accounting for income from non-farm sources. A large proportion of agricultural households in Jharkhand, Bihar, Odisha, Uttar Pradesh, West Bengal and Madhya Pradesh are unable to obtain a subsistence level of income. JEL Codes: Q12, D31, R20
Estimation of SAM for India: An Application for India’s Energy Transition Targets
Authors: Chaudhuri Chetana , Pratap Devender , Pohit Sanjib 
Published: October 2024

The social accounting matrix (SAM) for India was historically constructed based on the input–output table (IOT). However, since 2011–2012, the Government of India has been publishing the supply–use table, instead of the IOT. While the erstwhile IOT, published by the Government of India, had the same number of products and industries, the supply–use table provides one ‘supply matrix’ and one ‘use matrix’, each of which is a rectangular table with 140 products and 66 industries (for 2018–2019). Converting the supply–use table to a square IOT and subsequently extending it to SAM require the utilisation of various data sources, numerous steps and adjustments. Despite the usefulness of both IO and SAM matrices in macroeconomic policy design, not much literature is available on these. This study aims to bridge the gap by constructing IOT and SAM for India from the supply–use table incorporating information from many other sources and describing the method of construction of the matrices. Our IO and SAM also focus on various energy sectors, including different sources of power generation, biomass and so on, and disaggregate energy-intensive sectors like cement or aluminium, considering the immense usefulness of the energy-extended macro-structure to the research of energy and environment policies. The study focuses on the construction of a 59 × 59 SAM for India, with the base year of 2021–2022 incorporating three factors of production and ten categories of households. As an application of the newly constructed SAM, we have analysed the employment implication of India’s Nationally Determined Contribution emission commitments. JEL Codes: E16, C67, D57
Correlates of Lifestyle Physical Activity Among Young Arab American Women
Authors: Mansuri Sudaba , Daniel Manju N. , Halloway Shannon , Abboud Sarah , Schoeny Michael E. , Buchholz Susan W. 
Published: October 2024

Background: Young Arab American women are at risk for cardiovascular disease, but there is limited data on their physical activity (PA) engagement. Objectives: The aim of this study was to examine the relationship between PA and its correlates in young Arab American women. The objectives of this study were to: (1) describe self-reported lifestyle PA behaviors of young Arab American women and (2) examine the relationship between their self-reported lifestyle PA, device-measured lifestyle PA (combined moderate /vigorous and steps), and potentially associated factors (demographics, physical measures, individual factors, and behavior cognition factors). Methods: This cross-sectional study was conducted with women 18 to 35 years of age and Arab American (n = 50) in the Midwest Region of the United States. Participants wore ActiGraph GT3X-BT monitors for 7 days; self-report measures included the International Physical Activity Questionnaire, demographics, acculturation, discrimination, religiosity, self-efficacy, and social support. Results: The mean age of participants was 25.5 years ( SD: 5.5; range: 18-35). Per ActiGraph, the average daily steps were 5946 ( SD: 2783); only 24% met the moderate-intensity PA guidelines. Self-efficacy was significantly associated with increased moderate-to-vigorous PA ( B = 0.37; P = .012). Conclusion: The average daily steps for the young Arab American women in this study were of low active classification. More than 75% of the women failed to meet the recommended weekly moderate /vigorous PA guidelines. Our study supports the importance of targeting and tailoring PA interventions on young Arab American women who have low self-efficacy for overcoming barriers to lifestyle PA.
A Study of the Impact of Crypto Assets on Portfolio Risk Management (2019–2022)
Authors: Jotaki Hiroaki , Liu Mengyao , Takahashi Hiroshi 
Published: October 2024

In this study, we examined the impact of crypto assets on the risk-return characteristics of portfolios consisting of traditional assets. First, we examined the optimal portfolio for maximising the Sharpe ratio and found that the Sharpe ratio improves when CMC Crypto 200 Index (CMC) are incorporated to a certain extent into a portfolio consisting of traditional stocks, bonds and commodity indices. In addition, we focused on individual assets comprising crypto assets instead of CMC and incorporated individual crypto assets into a portfolio of conventional traditional assets and found that the Sharpe ratio improved for the majority of individual crypto assets. This is an interesting result as it indicates that crypto assets may contribute to improving the risk-return characteristics of the portfolio. Second, we examined the optimal portfolio for minimising volatility and found that the percentage of crypto assets held was small. This may be due to the fact that the volatility of crypto assets is higher than that of other assets. In this sense, investing in cryptocurrencies is not suitable for investors who want to keep volatility low. JEL Codes: G10, G11, G12
Pharmaceutical Care in Patients with Side Effects to Oral Antineoplastic Agents: A Case Report
Authors: Alarcon Teresa Chinchilla , Muñoz- Cejudo Belen Maria , Mora- Mora Maria Antonia 
Published: October 2024

Background Chronic myeloid leukaemia (CML) is a haematopoietic stem cell disease characterised by the proliferation of granulocytes and their immature myeloid precursors. The treatments recommended are oral treatments dispensed in the outpatient unit (OU) of the hospital’s pharmacy service (PS), where patient-centred pharmaceutical care (PC) is essential to enhance therapeutic adherence, detect drug interactions and create a pharmacist-patient relationship to educate the patient on the main potential toxicities derived from the treatment and warning signs or symptoms requiring immediate attention. Methodology We present the case of a 55-year-old woman, followed up in consultation by the Haematology Service (HS) since October 2021 for CML in the chronic phase. Results She started treatment on nilotinib 300 mg every 12 hours. The patient attended OU and was offered PC. After 12 months, nilotinib was well tolerated, but our patient experienced a loss of effectiveness, so HS decided to switch to dasatinib 100 mg daily. After one year of treatment, our patient was presented with symptoms of swelling and dyspnoea on moderate exertion. In January 2024, following a joint Haematology-Pharmacy session, a switch to bosutinib 400 mg daily was decided. After 15 days of treatment, the patient presented without an appointment due to a pruritic generalised rash on the torso, face, and extremities, being diagnosed with leukocytoclastic vasculitis. Conclusion In conclusion, we describe case reports of a patient who has a lack of effectiveness and ARs in several TKIs and the importance of identifying side effects, through early and close PC, in order for the patient’s evolution to be favourable.