bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of Maxillary Deformity with Segmental Osteotomy followed by Implant Insertion in β-Thalassemia Major Patient
Authors: Pektas Zafer Ozgur , Cubuk Secil , Kircelli Beyza , Uckan Sina 
Published: November 2015

ABSTRACT

Aim
The aim of this report is to present the management of the maxillary deformity and subsequent implant therapy of a case with β-thalassemia major.

Background
β-thalassemia is a hematologic disorder that results from the abnormality of the β-globulin chain synthesis. The best known thalassemia-induced dentofacial problem is the maxillary enlargement, and this undesirable growth of maxilla affects not only the facial esthetics but also dental occlusion, and leads to functional deficiency.

Case description
A 16-year-old female patient with â-thalassemia major was referred with the complaints of severe facial deformity and malocclusion, resulting in psychosocial and functional problems for her. The dentofacial deformity was characterized by an excessive premaxillary growth both in sagittal and vertical planes. Anterior maxillary osteotomy was performed with bilateral canines extraction, and dental implants were inserted to the canine regions, following bone healing. Postoperative course was free of problems with the crown restorations in function. Recurrence has not been occurred at 6 years follow-up.

Conclusion
With maintaining hemoglobin level over 10 gm/dl, correction of maxillary defects is stable for long-term in â-thalassemia major patient. Implant application to these patients may lead to unforeseeable results.

Clinical significance
Although having some difficulties, such as overbleeding and stability problems, maxillary enlargement can be treated by segmental osteotomies successfully in β-thalassemia major patient. Implant failure frequency may be higher, but many other studies are needed for determining implant survival rate in β-thalassemia major patients.

How to cite this article
Pektas ZO, Cubuk S, Kircelli B, Uckan S. Management of Maxillary Deformity with Segmental Osteotomy followed by Implant Insertion in β-Thalassemia Major Patient. J Contemp Dent Pract 2015;16(8):704-707.
The Japanese Comfort Women and Sexual Slavery during the China and Pacific Wars
Authors: Norma Caroline 
Published: November 2015

The Japanese military was responsible for the sexual enslavement of thousands of women and girls in Asia and the Pacific during the China and Pacific wars under the guise of providing ‘comfort’ for battle-weary troops. Campaigns for justice and reparations for ‘comfort women’ since the early 1990s have highlighted the magnitude of the human rights crimes committed against Korean, Chinese and other Asian women by Japanese soldiers after they invaded the Chinese mainland in 1937. These campaigns, however, say little about the origins of the system or its initial victims.
The Japanese Comfort Women and Sexual Slavery during the China and Pacific Wars explores the origins of the Japanese military’s system of sexual slavery and illustrates how Japanese women were its initial victims.
Aesthetics of Displacement: Turkey and its Minorities on Screen
Authors: Köksal Özlem 
Published: November 2015

Displacement does not only have an effect on groups’ and individuals’ ways of relating to their identity and their past but the knowledge and experience of it also has an impact on its representation. Looking at films that represent the experience of displacement in relation to Turkey’s minorities, Aesthetics of Displacement argues that there is a particular aesthetic continuity among the otherwise unrelated films. Özlem Köksal focuses on films that bring taboo issues concerning the repression of minorities into visibility, arguing that the changing political and social conditions determine not only the types of stories told but also the ways in which these stories are told.
Focusing on aesthetic and narrative continuities, the films discussed include Ararat, Waiting for the Clouds and Once Upon a Time in Anatolia among others. Each film is examined in light of major historical event(s) and their context (political and social) as well as the impact these events had on the construction of both minority and Turkish identity.
A Management Strategy for the Improvement of Private Universities Lecturers’ Professional Competences
Authors: Suhaemi Mimin Emi , Aedi Nur 
Published: November 2015

<p class="apa">Lecturers are professional educators and scientists whose main job is to transform, develop, and disseminate knowledge, technology, and art through education, research and community services. As professionals, in Indonesia, lecturers are expected to possess pedagogic, personal, social, and professional competences. However, in reality, the professional competences of private university lecturers are still low. It has been established that the masterly of learning materials, the understanding of the pedagogic content and substance, and the use of appropriate teaching and learning methodologies are still low. Thus, the present study aimed to reveal, explain, and find a model of management which can better improve services in the private universities across Indonesia, especially, the improvement of lecturers’ professional competences. The research employed a descriptive-analytic method, which aimed to reveal current events that impact positively on the improvement of private university lecturers’ professional competences. This research, has revealed that the policies of lecturer planning and preparation by teacher training institutions are still weak and less concerned with the aspect of needs assessment or mapping; lecturer competence development has not been handled sufficiently thus, ignoring the stduents needs; the management strategy of lecturers’ competence improvement has not been well-coordinated; the management aspect as well as lecturer continuous professional development has failed to consider reward and punishment, hence affecting lecturer competences. In the effort for further clarification, SWOT analysis was applied which also revealed that among the factors supporting lecturer development was the high motivation and othe inner personal factors. This means there should be special strategies of management development that positively influence lecturer professional competences and quality.</p>
Recycled oceanic crust and marine sediment in the source of alkali basalts in Shandong, eastern China: Evidence from magma water content and oxygen isotopes
Authors: Liu Jia , Xia Qun‐Ke , Deloule Etienne , Chen Huan , Feng Min 
Published: November 2015

AbstractThe magma water contents and cpx δ18O values in alkali basalts from the Fuyanyshan (FYS) volcano in Shandong, eastern China, were investigated by an inverse calculation based on the water content of clinopyroxene (cpx) phenocrysts, the ivAlcpx‐dependent water partitioning coefficient
, and secondary ion mass spectrometer, respectively. The calculated water content (H2O wt.) of magma ranges from 0.58% to 3.89%. It positively correlates with heavy rare earth element concentrations and bulk rock 87Sr/86Sr ratios, and it negatively correlates with Nb/U ratios. However, it is not correlated with bulk Mg# (Mg# = 100 × Mg / (Mg + Fe)) and (La/Yb)n (n represents primitive mantle normalization). Combined with the rather homogenous distribution of water content within cpx grains, these correlations indicate that the water variations among different samples represent the original magma signature, rather than results of a shallow process, such as degassing and diffusion. The δ18O of cpx phenocrysts varies from 3.6‰ to 6.3‰ (±0.5‰, 2SD), which may be best explained by the involvement of components from the lower and upper oceanic crust with marine sediments within the mantle source. The H2O/Ce ratios of the calculated melts range from 113 to 696 and form a positive trend with bulk rock 87Sr/86Sr, which cannot be explained by the recycled Sulu eclogite or by the metasomatized lithospheric mantle. Our modeling calculation shows that the decoupling of εHf and εNd could be caused by the involvement of marine sediments. Combing the high Ba/Th ratios, positive Sr spikes, and low Ce/Pb ratios for the Fuyanshan basalts, we suggest that the hydrous nature of the FYS basalts was derived from the hydrous mantle transition zone with ancient sediments.
Radar‐observed diurnal cycle and propagation of convection over the Pearl River Delta during Mei‐Yu season
Authors: Chen Xingchao , Zhao Kun , Xue Ming , Zhou Bowen , Huang Xuanxuan , Xu Weixin 
Published: November 2015

AbstractUsing operational Doppler radar and regional reanalysis data from 2007–2009, the climatology and physical mechanisms of the diurnal cycle and propagation of convection over the Pearl River Delta (PRD) region of China during the Mei‐Yu seasons are investigated. Analyses reveal two hot spots for convection: one along the south coastline of PRD and the other on the windward slope of mountains in the northeastern part of PRD. Overall, convection occurs most frequently during the afternoon over PRD due to solar heating. On the windward slope of the mountains, convection occurrence frequency exhibits two daily peaks, with the primary peak in the afternoon and the secondary peak from midnight to early morning. The nighttime peak is shown to be closely related to the nocturnal acceleration and enhanced lifting on the windward slope of southwesterly boundary layer flow, in the form of boundary layer low‐level jet. Along the coastline, nighttime convection is induced by the convergence between the prevailing onshore wind and the thermally induced land breeze in the early morning. Convection on the windward slope of the mountainous area is more or less stationary. Convection initiated near the coastline along the land breeze front tends to propagate inland from early morning to early afternoon when land breeze cedes to sea breeze and the prevailing onshore flow.
Characterizing the lifetime and occurrence of stratospheric‐tropospheric exchange events in the rocky mountain region using high‐resolution ozone measurements
Authors: Sullivan John T. , McGee Thomas J. , Thompson Anne M. , Pierce R. Bradley , Sumnicht Grant K. , Twigg Laurence W. , Eloranta Edwin , Hoff Raymond M. 
Published: November 2015

AbstractThe evolution of a Stratospheric‐Tropospheric Exchange (STE) event from 4 to 8 August 2014 at Fort Collins, Colorado, is described. The event is characterized with observations from the Goddard Space Flight Center TROPospheric OZone (TROPOZ) Differential Absorption Lidar, the University of Wisconsin High Spectral Resolution Lidar, and multiple ozonesondes during NASA's Deriving Information on Surface Conditions from Column and Vertically Resolved Observations Relevant to Air Quality and the Front Range Air Pollution and Photochemistry Experiment (FRAPPE) campaigns. Based on the extended TROPOZ observations throughout the entire campaign, it was found that STE events have largely contributed to an additional 10–30 ppbv of ozone at Fort Collins. Additional measurements of ozone and relative humidity from the Atmospheric Infrared Sounder are characterize the transport of the intrusion. The Real‐time Air Quality Modeling System simulated ozone agrees well with the TROPOZ ozone concentrations and altitude during the STE event. To extend the analysis into other seasons and years, the modeled ozone to potential vorticity ratio is used as a tracer for stratospheric air residing below the tropopause. It is found that at Fort Collins, CO, and depending on season from 2012 to 2014, between 18 and 31% of tropospheric ozone corresponds to stratospheric air. A relationship to determine the lifetime of stratospheric air below the tropopause is derived using the simulated ratio tracer. Results indicate that throughout summer 2014, 43% of stratospheric air resided below the tropopause for less than 12 h. However, nearly 39% persisted below the tropopause for 12–48 h and likely penetrated deeper in the troposphere.
The carbon balance pivot point of southwestern U.S. semiarid ecosystems: Insights from the 21st century drought
Authors: Scott Russell L. , Biederman Joel A. , Hamerlynck Erik P. , Barron‐Gafford Greg A. 
Published: November 2015

AbstractGlobal‐scale studies indicate that semiarid regions strongly regulate the terrestrial carbon sink. However, we lack understanding of how climatic shifts, such as decadal drought, impact carbon sequestration across the wide range of structural diversity in semiarid ecosystems. Therefore, we used eddy covariance measurements to quantify how net ecosystem production of carbon dioxide (NEP) differed with relative grass and woody plant abundance over the last decade of drought in four Southwest U.S. ecosystems. We identified a precipitation “pivot point” in the carbon balance for each ecosystem where annual NEP switched from negative to positive. Ecosystems with grass had pivot points closer to the drought period precipitation than the predrought average, making them more likely to be carbon sinks (and a grass‐free shrubland, a carbon source) during the current drought. One reason for this is that the grassland located closest to the shrubland supported higher leaf area and photosynthesis at the same water availability. Higher leaf area was associated with a greater proportion of evapotranspiration being transpiration (T/ET), and therefore with higher ecosystem water use efficiency (gross ecosystem photosynthesis/ET). Our findings strongly show that water availability is a primary driver of both gross and net semiarid productivity and illustrate that structural differences may contribute to the speed at which ecosystem carbon cycling adjusts to climatic shifts.
Synthesis of D‐Desosamine and Analogs by Rapid Assembly of 3‐Amino Sugars
Authors: Zhang Ziyang , Fukuzaki Takehiro , Myers Andrew G. 
Published: November 2015

AbstractD‐Desosamine is synthesized in 4 steps from methyl vinyl ketone and sodium nitrite. The key step in this chromatography‐free synthesis is the coupling of (R)‐4‐nitro‐2‐butanol and glyoxal (trimeric form) mediated by cesium carbonate, which affords in crystalline form 3‐nitro‐3,4,6‐trideoxy‐α‐D‐glucose, a nitro sugar stereochemically homologous to D‐desosamine. This strategy has enabled the syntheses of an array of analogous 3‐nitro sugars. In each case the 3‐nitro sugars are obtained in pure form by crystallization.
Incorporation of a Non‐Natural Arginine Analogue into a Cyclic Peptide Leads to Formation of Positively Charged Nanofibers Capable of Gene Transfection
Authors: Li Mao , Ehlers Martin , Schlesiger Stefanie , Zellermann Elio , Knauer Shirley K. , Schmuck Carsten 
Published: November 2015

AbstractFunctionalization of the tetracationic cyclic peptide (Ka)4 with a single guanidiniocarbonyl pyrrole (GCP) moiety, a weakly basic but highly efficient arginine analogue, completely alters the self‐assembly properties of the peptide. In contrast to the nonfunctionalized peptide 2, which does not self‐assemble, GCP‐containing peptide 1 forms cationic nanofibers of micrometer length. These aggregates are efficient gene transfection vectors. DNA binds to their cationic surface and is efficiently delivered into cells.
Magnetic “Molecular Oligomers” Based on Decametallic Supertetrahedra: A Giant Mn49 Cuboctahedron and its Mn25Na4 Fragment
Authors: Manoli Maria , Alexandrou Sofia , Pham Linh , Lorusso Giulia , Wernsdorfer Wolfgang , Evangelisti Marco , Christou George , Tasiopoulos Anastasios J. 
Published: November 2015

AbstractTwo nanosized Mn49 and Mn25Na4 clusters based on analogues of the high‐spin (S=22) [MnIII6MnII4(μ4‐O)4]18+ supertetrahedral core are reported. Mn49 and Mn25Na4 complexes consist of eight and four decametallic supertetrahedral subunits, respectively, display high virtual symmetry (Oh), and are unique examples of clusters based on a large number of tightly linked high nuclearity magnetic units. The complexes also have large spin ground‐state values (Mn49: S=61/2; Mn25Na4: S=51/2) with the Mn49 cluster displaying single‐molecule magnet (SMM) behavior and being the second largest reported homometallic SMM.
Hydrogen Bond Fluctuations Control Photochromism in a Reversibly Photo‐Switchable Fluorescent Protein
Authors: Morozov Dmitry , Groenhof Gerrit 
Published: November 2015

AbstractReversibly switchable fluorescent proteins (RSFPs) are essential for high‐resolution microscopy of biological samples, but the reason why these proteins are photochromic is still poorly understood. To address this problem, we performed molecular dynamics simulations of the fast switching Met159Thr mutant of the RSFP Dronpa. Our simulations revealed a ground state structural heterogeneity in the chromophore pocket that consists of three populations with one, two, or three hydrogen bonds to the phenolate moiety of the chromophore. By means of non‐adiabatic quantum mechanics/molecular dynamics simulations, we demonstrated that the subpopulation with a single hydrogen bond is responsible for off‐switching through photo‐isomerization of the chromophore, whereas two or more hydrogen bonds inhibit the isomerization and promote fluorescence instead. While rational design of new RSFPs has so far focused on structure alone, our results suggest that structural heterogeneity must be considered as well.
Concise Asymmetric Construction of C2‐symmetric 1,9‐Diarylnonanoids Using a Hypervalent Silicon Complex: Total Synthesis of (−)‐Ericanone
Authors: Kotani Shunsuke , Kai Kosuke , Shimoda Yasushi , Hu Hao , Gao Shen , Sugiura Masaharu , Ogasawara Masamichi , Nakajima Makoto 
Published: November 2015

AbstractBy using a phosphine oxide‐catalyzed enantioselective double aldol reaction, we achieved the concise construction of C2‐symmetric 1,9‐diarylnonanoids, enabling the synthesis of (−)‐ericanone from p‐hydroxybenzaldehyde in 6 steps with 65 % overall yield. The enantioselective double aldol reaction is useful for establishing C2‐symmetric 1,9‐diaryl‐3,7‐dihydroxy‐5‐nonanones with a single operation. Furthermore, the use of o‐nosyl‐protected p‐hydroxybenzaldehyde and a 4,4′‐disubstituted BINAP dioxide catalyst dramatically improved the reactivity and selectivity in the double aldol reaction, enabling the total synthesis of (−)‐ericanone with high yield and with excellent enantiopurity.
Rationale, design and methodology of the image analysis protocol for studies of patients with cerebral small vessel disease and mild stroke
Authors: Valdés Hernández Maria del C. , Armitage Paul A. , Thrippleton Michael J. , Chappell Francesca , Sandeman Elaine , Muñoz Maniega Susana , Shuler Kirsten , Wardlaw Joanna M. 
Published: November 2015

AbstractRationaleCerebral small vessel disease (SVD) is common in ageing and patients with dementia and stroke. Its manifestations on magnetic resonance imaging (MRI) include white matter hyperintensities, lacunes, microbleeds, perivascular spaces, small subcortical infarcts, and brain atrophy. Many studies focus only on one of these manifestations. A protocol for the differential assessment of all these features is, therefore, needed.AimsTo identify ways of quantifying imaging markers in research of patients with SVD and operationalize the recommendations from the STandards for ReportIng Vascular changes on nEuroimaging guidelines. Here, we report the rationale, design, and methodology of a brain image analysis protocol based on our experience from observational longitudinal studies of patients with nondisabling stroke.DesignThe MRI analysis protocol is designed to provide quantitative and qualitative measures of disease evolution including: acute and old stroke lesions, lacunes, tissue loss due to stroke, perivascular spaces, microbleeds, macrohemorrhages, iron deposition in basal ganglia, substantia nigra and brain stem, brain atrophy, and white matter hyperintensities, with the latter separated into intense and less intense. Quantitative measures of tissue integrity such as diffusion fractional anisotropy, mean diffusivity, and the longitudinal relaxation time are assessed in regions of interest manually placed in anatomically and functionally relevant locations, and in others derived from feature extraction pipelines and tissue segmentation methods. Morphological changes that relate to cognitive deficits after stroke, analyzed through shape models of subcortical structures, complete the multiparametric image analysis protocol.OutcomesFinal outcomes include guidance for identifying ways to minimize bias and confounds in the assessment of SVD and stroke imaging biomarkers. It is intended that this information will inform the design of studies to examine the underlying pathophysiology of SVD and stroke, and to provide reliable, quantitative outcomes in trials of new therapies and preventative strategies.
Unravelling Surface Composition of Bimetallic Nanoparticles
Authors: Chen Ching‐Hsiang , Pan Chun‐Jern , Su Wei‐Nien , Sarma Loka Subramanyam , Andra Cun Cun Al , Sheu Hwo‐Shuenn , Liu Din‐Goa , Lee Jyh‐Fu , Hwang Bing‐Joe 
Published: November 2015

AbstractAccurately determining the surface composition of bimetallic nanoparticles (bi‐MNPs) is crucial in assessing their catalytic potential for energy applications and surface‐enhanced Raman scattering (SERS). Despite its importance, characterizing the surface composition of bi‐MNPs is still extremely difficult with existing techniques. Here, we show that the challenge is approached by combining extended X‐ray absorption fine structure (EXAFS) analyses and modeling calculations. A generally applicable methodology using an ethylene glycol‐assisted redox transmetallation (EG‐RTM) strategy has been used to deduce the surface Pt composition of various Pt–Ru bi‐MNPs to facilitate discussion of their electrochemical catalytic efficiency. Further discussion is focused on SERS, related to the surface Ag content of various Ag–Pt bi‐MNPs formed in ethylene glycol solutions at controlled pH values. Although the present methodology is demonstrated on fcc structured bi‐MNPs it should be transferable to bi‐MNP structures with different shapes and also to ternary nanoparticles. The proposed methodology enables us to deduce the surface composition of bi‐MNPs from experimental data directly and to estimate the surface composition under real conditions, when compared to simulation. The ability of the present combined modeling and experimental approach makes it a unique tool in our quest to understand the physical and chemical properties of NPs.
Alkanes from Bioderived Furans by using Metal Triflates and Palladium‐Catalyzed Hydrodeoxygenation of Cyclic Ethers
Authors: Song Hai‐Jie , Deng Jin , Cui Min‐Shu , Li Xing‐Long , Liu Xin‐Xin , Zhu Rui , Wu Wei‐Peng , Fu Yao 
Published: November 2015

AbstractUsing a metal triflate and Pd/C as catalysts, alkanes were prepared from bioderived furans in a one‐pot hydrodeoxygenation (HDO) process. During the reaction, the metal triflate plays a crucial role in the ring‐opening HDO of furan compounds. The entire reaction process has goes through two major phases: at low temperatures, saturation of the exocyclic double bond and furan ring are catalyzed by Pd/C; at high temperatures, the HDO of saturated furan compounds is catalyzed by the metal triflate. The reaction mechanism was verified by analyzing the changes of the intermediates during the reaction. In addition, different metal triflates, solvents, and catalyst recycling were also investigated.