bluuebunny/crossref_metadata_2025_split huggingface dataset:
How coping styles, cognitive distortions, and attachment predict problem gambling among adolescents and young adults
Authors: Calado Filipa , Alexandre Joana , Griffiths Mark D. 
Published: October 2017

Background and aims
Recent research suggests that youth problem gambling is associated with several factors, but little is known how these factors might influence or interact each other in predicting this behavior. Consequently, this is the first study to examine the mediation effect of coping styles in the relationship between attachment to parental figures and problem gambling.

Methods
A total of 988 adolescents and emerging adults were recruited to participate. The first set of analyses tested the adequacy of a model comprising biological, cognitive, and family variables in predicting youth problem gambling. The second set of analyses explored the relationship between family and individual variables in problem gambling behavior.

Results
The results of the first set of analyses demonstrated that the individual factors of gender, cognitive distortions, and coping styles showed a significant predictive effect on youth problematic gambling, and the family factors of attachment and family structure did not reveal a significant influence on this behavior. The results of the second set of analyses demonstrated that the attachment dimension of angry distress exerted a more indirect influence on problematic gambling, through emotion-focused coping style.

Discussion
This study revealed that some family variables can have a more indirect effect on youth gambling behavior and provided some insights in how some factors interact in predicting problem gambling.

Conclusion
These findings suggest that youth gambling is a multifaceted phenomenon, and that the indirect effects of family variables are important in estimating the complex social forces that might inﬂuence adolescent decisions to gamble.
ВИКОРИСТАННЯ ЗЕРНОВИХ ДОБАВОК У ВИРОБНИЦТВІ МОЛОЧНИХ ПРОДУКТІВ З КОМБІНОВАНИМ СКЛАДОМ С И РОВИНИ
Authors: РОМАНЧУК І. О. 
Published: October 2017

У раціоні людей різних вікових груп молочні продукти традиційно займають суттєву частку. Особливо користуються попитом кисломолочні продукти. Технології виробництва резервуарним способом передбачають механічне оброблення кисломолочного згустку, а термізованих продуктів - термомеханічне, в результаті чого може порушуватися структура продукту, відбутися відділення сироватки та розшарування готового продукту. Для запобігання появі недоліків консистенції широко використовують стабілізатори структури. Переважна більшість стабілізаторів, що виконують функції загущувачів та гелеутворювачів, за своєю природою – гідрофільні речовини, які завдяки зв’язуванню вільної вологи та підвищенню в’язкості сумішей, забезпечують утворення необхідної структури. Для продуктів переробки зернових культур такі властивості обумовлені, в першу чергу, наявністю вуглеводів, в меншій мірі – білками та баластними речовинами. Сучасні технології переробки зернових дозволяють одержувати інгредієнти і продукти, які можуть використовуватися в якості структуроутворювачів під час виробництва молочних продуктів з комбінованим складом сировини. Проведено аналіз структуроутворювачів, зокрема, желатину, агару, альгінату натрію, модифікованого крохмалю, рисового борошна, пшеничного та кукурудзяного зернопродуктів для виробництва кисломолочних продуктів. Основними критеріями відбору структуроутворювачів були діапазон температур, за яких стабілізатори виявляли свої гелеутворювальні властивості, вологоутримувальна здатність, в’язкість, здатність до утворення однорідної суміші під час зберігання кисломолочних продуктів. Опрацьовано способи застосування рисового борошна за температури пастеризації сумішей (82±2)0С для кисломолочних напоїв, пшеничного та кукурудзяного зернопродуктів за температури термізації сумішей (74±2)0С для термізованих сиркових виробів. Обґрунтовано використання продуктів переробки зернових, які покращують органолептичні та реологічні показники готового продукту. Розроблено технологічну схему та визначено режими технологічних операцій під час виробництва молочних продуктів з комбінованим складом сировини.
ALKFusions in a Wide Variety of Tumor Types Respond to Anti-ALK Targeted Therapy
Authors: Ross Jeffrey S. , Ali Siraj M. , Fasan Omotayo , Block Jared , Pal Sumanta , Elvin Julia A. , Schrock Alexa B. , Suh James , Nozad Sahar , Kim Sungeun , Jeong Lee Hwa , Sheehan Christine E. , Jones David M. , Vergilio Jo-Anne , Ramkissoon Shakti , Severson Eric , Daniel Sugganth , Fabrizio David , Frampton Garrett , Miller Vince A. , Stephens Philip J. , Gay Laurie M. 
Published: October 2017

AbstractBackgroundGenomic fusions of the anaplastic lymphoma kinase gene (ALK) are a well-established therapy target in non-small cell lung cancer (NSCLC). From a survey of 114,200 clinical cases, we determined the prevalence of ALK rearrangements (rALK) in non-NSCLC tumors and report their responsiveness to therapies targeting ALK.Materials and MethodsComprehensive genomic profiling of 114,200 relapsed and metastatic malignancies, including both solid tumors and hematolymphoid cancers, was performed using a hybrid-capture, adaptor ligation-based next-generation sequencing assay.ResultsOf 114,200 clinical samples, 21,522 (18.8%) were NSCLC and 92,678 (81.2%) were other tumor types. Of the 876 (0.8%) cases with ALK fusions (fALK) or rALK, 675 (77.1%) were NSCLC and 201 (22.9%) were other tumor types. ALK fusions were significantly more frequent in NSCLC (3.1%) than non-NSCLC (0.2%; p &lt; .0001). Patients with non-NSCLC tumors harboring fALK were significantly younger (p &lt; .0001) and more often female (p &lt; .0001) than patients with fALK-positive NSCLC. EML4 was more often the fusion partner in NSCLC (83.5%) versus non-NSCLC tumors (30.9%; p &lt; .0001).ConclusionALK rearrangements can be identified in a wide variety of epithelial and mesenchymal malignancies beyond NSCLC. Anti-ALK therapies can be effective in non-NSCLC tumors driven by fALK, and further study of therapies targeting ALK in clinical trials involving a wider variety of cancer types appears warranted.
Desplazamiento forzado y restitución de tierras en Colombia: Una búsqueda de garantías de no repetición
Authors: Cifuentes Chaparro Sneither Efraín 
Published: October 2017

El presente artículo afirma que, en el contexto de justicia transicional colombiano, el éxito de la política de restitución de tierras depende, en buena medida, de la capacidad institucional para contrarrestar las causas y consecuencias del desplazamiento forzado interno.
De esta forma, explica que la mayoría de las víctimas desplazadas forzadamente pertenecen a grupos poblacionales históricamente marginados y excluidos en el ejercicio de sus derechos; identifica cuáles han sido los principales factores de despojo y abandono forzado de tierras vinculados al desplazamiento forzado que permiten explicarlo como una práctica de guerra para la acumulación; aborda la política pública de atención a la población desplazada forzadamente como una suma de esfuerzos insuficientes para superar el estados de cosas inconstitucional declarado en 2004; y, a partir de ello, reflexiona sobre las limitaciones de la política de restitución de tierras, luego de cumplirse cinco años de su implementación, para el retorno y/o reubicación de las víctimas, bajo garantías de no repetición de los hechos que dieron lugar a las violaciones masivas y sistemáticas a sus Derechos Humanos.
La extensión de jurisprudencia como aporte al procedimiento administrativo colombiano
Authors: Castro López Angie Marcela , Peña Rodríguez Diana Marcela 
Published: October 2017

En el presente artículo desarrollamos el mecanismo creado en el nuevo Código de Procedimiento Administrativo y de lo Contencioso Administrativo, denominado extensión de jurisprudencia, donde como objetivo principal estableceremos su naturaleza jurídica la cual nos permitirá identificar aspectos positivos y negativos encontrados desde su creación, procedimiento y aplicación, dentro del sistema judicial colombiano.
Nuestro artículo busca dar respuesta al siguiente interrogante: ¿Cuáles son las fortalezas y deficiencias de la extensión de jurisprudencia?
Para desarrollar el problema de investigación, y dar respuesta a él, hemos acudido al método cualitativo, apoyándonos en jurisprudencia de las altas cortes, memorias de congresos, foros, debates con ocasión a la presentación de la Ley 1437 de 2011, artículos e información en las páginas oficiales de entidades estatales de todo esto realizamos un análisis y comprensión de la nueva figura, llevándonos a encontrar la ardua labor que deberán desempeñar las entidades Administrativas.
Evaluation of student assessment practices in a medical college
Authors: Elfaki Omer A. , Alamri Abdulaziz A. 
Published: October 2017

Background: The importance of students’ assessment and its role in driving students learning are well recognized. Guidelines for good assessment practice have been developed. The GMC issued important recommendations related to assessment of students’ performance to be followed by medical schools in UK. The Liaison Committee on Medical Education (LCME) developed standards emphasizing the importance of documenting students’ performance. The utility concept of an assessment tool had been proposed by Van der Vleuten stating a number of weighted criteria. Assessment of clinical competence was proposed to be well covered by the model of Miller. No single method of assessment can be recommended to be appropriate for all assessment purposes and all domains of competence. Therefore, multiple methods of assessment are required.Methods: There are 35 courses included in the MBBS program in the college of medicine, KKU. these are taught over five years in addition to a preparatory year and the internship year. the curriculum can still be described as discipline based. a survey was planned to study the current assessment situation. this is a cross-sectional descriptive study. the data collection methods used were survey and study of the documents of the courses. an online questionnaire was developed. the responses were analyzed using descriptive statistics to determine frequencies, averages and percentages. the study was conducted during the period January-May 2014.Results: Twenty course coordinators responded to the survey (57%). Eleven of the courses covered were basic and nine were clinical. Multiple tests as well as multiple methods of continuous assessment were used in the courses studied. Some of the methods used for summative assessment are no longer recommended in current assessment practices in medical education. Real OSCE was used only in one clinical course. Standard setting methods were not used and a fixed pass mark was used instead.Conclusions: Important shortcomings in student assessment system in many of the courses studied were identified. Less educationally desirable assessment methods and practices are still used in some courses such as unattended single long case examination. More attention should be given to technical aspects of assessment.
Brown Jaw Tumors: challenges and outcomes
Authors: Abdelrahman Tarek Elsayed Ftohy 
Published: October 2017

Background: Brown tumors are very rare giant cell lesions that arise as a result of hyperparathyroidism, brown tumors rarely affect the mandible and maxilla and its diagnosis and treatment is very challenging and needs a high index of suspicion.Methods: Retrospective chart review of nine cases diagnosed as brown jaw tumors treated in maxillofacial, head and neck surgery unit, department of surgery, Sohag University hospital.Results: They were 9 patients, 3 males and 6 females with a mean age of 43.3 years. Lesions were located in the mandible (4 cases), maxilla (3 cases), both mandible and maxilla (2 cases). The main presentation was a mass lesion. Clinical examination and serum parathormone, serum calcium, serum phosphorus, neck ultrasonography, parathyroid scan was used for diagnosis. Cases did excision with parathyroidectomy. There was no recurrence during a mean follow up period of 9.3 months. All patients had satisfactory results.Conclusions: All cases with osteolytic lesions in mandible or maxilla the possibility of brown tumors should be kept in mind especially if there is any manifestation of hyperparathyroidism. This report will aid in the recognition and treatment of the jaw brown tumors.
Pilonidal sinus- limberg versus karidakis flap our experience at SIMS, Shivamogga
Authors: A. Madhusudhan , Swamy Madhan D. P. , Arif Mohhamad 
Published: October 2017

Background: The etiology and pathogenesis of sacro-coccygeal pilonidal sinus are not clear. The pathogenesis of the disease is hypothesized to be related to the accumulation of weak and lifeless hair in the intergluteal region, which over time gives rise to foreign body reaction, causing abscess and sinus formation. A deep natal cleft with one of favourable factors enhance sacro-coccygeal pilonidal sinus, e.g., sweating, maceration, bacterial contamination and penetration of hairs. Obesity, trauma, local irritation and a sedentary lifestyle are usually associated with PS. Although pilonidal sinus can be treated using various conservative and surgical methods, recurrence rate remains high. Complete surgical removal of the pilonidal sinus or sinuses and appropriate reconstruction can lead to successful recovery. However, collection of the lifeless hair depends on the anatomy of the intergluteal area, and accompanying risk factors can lead to subsequent recurrence.Methods: The objective of this study is to compare the immediate post-operative and long-term results of Limberg flap and Karydakis flap, which are being widely used now to treat pilonidal sinus disease. It was a retrospective observational study where the patients (total number of patients-30) who underwent both the procedures were compared, Limberg flap (LF; n = 13) and Karydakis flap (KF; n = 17).Results: Present study found out that short and long-term results of the LF and KF procedures are similar. In present study we also noted that all patients with pilonidal sinus disease were men, and most of them had jobs which involved sitting for long durations. Poor hygiene and hirsutism however was not noted in most of the patients, and was not objectively assessed.Conclusions: Both the techniques can be used safely and effectively in sacro coccygeal pilonidal sinus disease.
A comparative evaluation of Transurethral Electro-Vaporisation of Prostate (TUEVP) versus Transurethral Resection of Prostate (TURP) for Benign Prostatic Hyperplasia (BPH)
Authors: Saini Rijul , Saxena Kartik , Makkar Gourav S. , Shivam Shekhar , Desai Sandip , Singh Shivam , Gupta Nishi 
Published: October 2017

Background: Transurethral Resection of Prostate (TURP) has been gold standard of surgical treatment of BPH but nonetheless it is associated with many complications. Transurethral Electro-Vaporisation of Prostate (TUEVP) is a new promising modality which has similar results and better side effect profile.Methods: A prospective, randomised, comparative study was conducted on seventy patients with symptomatic BPH in the Surgery department of Sanjay Gandhi Memorial Hospital, Delhi over two years starting from December 2014. These patients were randomly assigned to two groups- A and B using online random number generator. Patients of group A underwent TUEVP and those of group B underwent TURP. Overall patient satisfaction, patient safety, procedural efficacy and operative ease of the surgeon were compared.Results: Mean operative time (42.1 min in TUEVP and 38.4 min in TURP) and complication rates (14.3% in TUEVP and 11.4% in TURP) were comparable in both groups. Intra-operative bleeding was significantly less (2.9% in TUEVP; 22.9% in TURP) and visual clarity of operative field was significantly better in TUEVP (persistently clear in 97.1% in TUEVP; 77.1% in TURP). The mean catheterisation time (1.14 days in TUEVP and 2.51 days in TURP) and hospitalisation time (2.14 days in TUEVP and 3.1 days in TURP) were significantly shorter in TUEVP.Conclusions: TUEVP is comparable to TURP in terms of patient satisfaction, safety, operative time and procedural efficacy. TUEVP has shorter duration of catheterisation and hospitalisation and is better than TURP in terms of intra-operative bleeding and operative ease of the surgeon.
Association between serum linezolid concentration and haematological toxic effects: a longitudinal study
Authors: Hombal Prashant R. , Gudadappanavar Anupama M. , Javali S. B. 
Published: October 2017

Background: Linezolid is a commonly used antibiotic and reported various drug related adverse effects mainly haematological toxicity like thrombocytopenia, leukopenia and anaemia. But a significant association between linezolid plasma concentration and drug related adverse effects are not documented yet. This longitudinal observational study aims to study the incidence of drug related haematological toxicities and its association with serum Linezolid concentration and also evaluate the clinical outcome.Methods: After obtaining informed consent, each patient (18-50years) was given linezolid (600mg/12hourly), and evaluated for haematological (haemoglobin, platelets, WBCs), renal (as serum creatinine), and hepatic (as serum transaminases status), together with an assessment of drug C min values. These evaluations were repeated once a week or in concomitance with the development of an adverse event up to the end of linezolid therapy. The parametric dependent ‘t’ test was applied (p<0.05) and normality of data were performed by Kolmogorov Smirnov test, follows normal distribution.Results: There was significant reduction in platelet count and haemoglobin value seen from baseline till end of treatment (p<0.001) and there was 13% reduction in WBC count in all patients on day 14 when compared to baseline (p<0.001) indicating haematological toxicity according to WHO toxicity grading scale. All the patients (n=8; 26.6%) who developed drug related haematological toxicity also showed comparable increase in plasma linezolid concentration (C min) >10mg/L at the end of 14days.Conclusions: The capability to monitor plasma linezolid concentration (C min; trough value) once a week may lead to a significant improvement in clinical use of the drug both in terms of efficacy and tolerability as the study observed that there is association between linezolid concentration and risk of developing drug related haematological toxicity.
A influência da apresentação do preço (em formato de áudio) sobre as percepções dos clientes
Authors: Rodrigues Hugo Leonardo , Mainardes Emerson Wagner 
Published: October 2017

Este estudo buscou por meio de experimentos verificar os impactos decorrentes da utilização do dígito “9” no formato de preços (na modalidade de áudio) sobre a percepção das pessoas. A pesquisa foi desenvolvida em 3 experimentos. Em cada um dos experimentos, os respondentes foram divididos em dois grupos, cada um com uma oferta em áudio e com formato de preço diferente (com e sem o dígito nove na oferta). As amostras eram semelhantes entre si. Como instrumento de análise foi utilizado o teste-t student. De um modo geral, os resultados do teste t evidenciaram que a utilização do dígito “9” no formato do preço pode impactar a percepção dos clientes quanto à avaliação do preço, à avaliação da oferta, à intenção de compra, à avaliação da propaganda, à indicação da loja, à avaliação das relações de custo versus benefício e à avaliação do formato da propaganda.
Análise da criação de valor em uma operação de leveraged buyout (LBO) No Brasil
Authors: Mitre Filho Marcelo , Albuquerque Andrei Aparecido de , Paixão Michel Augusto Santana da 
Published: October 2017

Fazendo uso de um modelo de negócio baseado na aquisição de empresas com potencial de crescimento, os private equities desenvolveram as leveraged buyouts (LBOs). Para a aquisição da empresa-alvo, utiliza-se a dívida como pagamento de parte significativa do valor da aquisição. Um dos principais objetivos das LBOs é possibilitar que entidades financeiras realizem um volume considerável de aquisições sem comprometer substancialmente o patrimônio e o capital próprio, mitigando o risco do investimento e maximizando o retorno. Este artigo visa analisar a criação de valor em uma operação de LBO no mercado brasileiro, através do uso do Economic Value Added (EVA®). O método de pesquisa empregado foi o ex post facto, baseado em uma pesquisa qualitativa. O resultado encontrado indica evidências inconclusivas quanto a destruição do valor em uma operação de LBO nacional, considerando outros possíveis elementos responsáveis pelo indicador EVA® negativo.
The effects on nutritional status, bowel habits and tolerance of a high- protein, high-calorie, fiber- and fructo-oligosaccharide-enriched enteral formula: Safety and Effectiveness of Enteral Nutrition in Spanish patients (SENS Study).
Authors: Cuesta Triana F 
Published: October 2017

Background: Enteral nutrition (EN) is an effective nutritional intervention for patients at risk of malnutrition or malnourished. However, complications such as gastrointestinal intolerance, hyperglycemia or refeeding syndrome can be triggered by EN.Aim: To investigate the effects of a tube feeding formula (TFF) on patients’ nutritional status, biochemical status, bowel habits and safety.Methodology: Observational, prospective and multicentre study. Patients ≥18 years, undernourished or at nutritional risk, who were prescribed a high-calorie, high-protein, fiber-fortified TFF (Jevity® Plus HP, Abbott Laboratories S.A) were included. Patients were evaluated over a period of 8 weeks [baseline (V1), 4 weeks (V2) and 8 weeks (V3)].Results: A statistically significant increase in weight (1.5 kg), body mass index (0.6 kg/m2) and nutritional intake (59,7 kcal/day) was observed between V1 and V2. Between V1 and V3, there was a statistically significant decrease in the percentage of individuals with abnormal biochemical markers for glucose, sodium, potassium, total protein and albumin. The number of patients’ bowel movements remained stable throughout the study with a mean of 1.1 daily bowel movements.Conclusion: The TFF was safe and well tolerated, improved patients’ nutritional status, and normalized electrolyte balance and blood glucose levels without altering patients’ bowel habits.
Slickwater Proppant Transport in Hydraulic Fractures: New Experimental Findings and Scalable Correlation
Authors: Alotaibi Msalli A. , Miskimins Jennifer L. 
Published: October 2017

Summary
Slickwater hydraulic fracturing is an important technology that has enabled the oil and gas industry to economically develop enormous unconventional resources. Despite its great success, this technology faces challenges, especially with proppant transport in complex fractures. Very limited work exists in the literature regarding slickwater proppant flow in subsidiary fractures or predictive correlations to estimate settled proppant-dune heights.
This paper provides a scalable correlation to predict dune height across a wide range of flow rates and proppant concentrations in the primary fracture. A unique feature of this correlation is its inclusion of the friction effect; roughness was introduced to the fracture-slot walls. A 30/70-mesh brown sand was used to conduct the slot-flow experiments and build the correlation. This paper also spotlights the proppant-transport mechanism during proppant-dune development in the primary fracture. Understanding this mechanism reveals key information regarding the horizontal and vertical settled-proppant-size distribution. In addition, experimental results are presented to answer the debatable question of whether slickwater can transport proppant into tertiary fractures. In fact, the data show that proppant in slickwater is not only capable of “turning the corner” but also developing high dune levels exceeding 97% of the tertiary fracture-slot heights.