bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of the upcycling trend using ultrafiltrate of water from the production of collagen from fish skin in hair care cosmetics
Authors: Igielska‐Kalwat Joanna , Kilian‐Pięta Ewa , Siedlecki Maciej 
Published: September 2024

AbstractThe aim of the research problem of the article was to try to popularize the upcycling trend in the production of sustainable cosmetics and to confirm their effectiveness. The development of recycled raw materials is a new discovery in the chemical industry. Manufacturers emphasize the production of more environmentally friendly raw materials. Conscious consumers choose cosmetics whose production is based on sustainable development. Instead of throwing away waste from various industries, let us use it to produce active substances used in hair cosmetics. The production of the collagen series was created in accordance with the principles of upcycling, which involves obtaining collagen water, which is waste generated during the production of supplements. The main goal of the work was to learn cosmetic recipes for styling, washing and conditioning hair based on collagen waste, as well as to compare the results of people using the product in question. The aim of the study was also to demonstrate the effectiveness of the treatment in preventing split ends and hair breakage, usually caused by mechanical stress (brushing), as well as to confirm the effectiveness of other tests. The article presents procedures and parameters confirming the effectiveness of treatment with the tested hair products. The following tests were carried out: hair thickness and density, colour uniformity, shine factor and scalp hydration. All parameters numerically confirmed the beneficial effects of products containing collagen water used in hair care.
Health risk assessment of metal contamination in Malaysian rice (Oryza sativa): The impact of parboiling on toxic metal reduction prior to cooking
Authors: Goh Ngee Chuang , Noor Nurul Shahfiza , Mohamed Rafeezul , Tualeka Abdul Rohim , Zabidi Muhammad Azrul , Aziz Mohd Yusmaidie 
Published: September 2024

SummaryMetal contamination in rice grains is a critical global issue, posing serious health risks and affecting food safety, especially in countries like Malaysia where rice is a staple food. This study aimed to assess the effectiveness of various cooking treatments, with a focus on parboiling before absorption cooking (PBA), in reducing metal contamination in Malaysian rice. Metal levels were measured using tandem inductively coupled plasma mass spectrometry (ICP‐MS/MS), and health risks were assessed following USEPA guidelines. Parboiling before absorption cooking was found to eliminate 77.9% of toxic metals and 68.4% of essential metals while keeping arsenic (As), cadmium (Cd) and lead (Pb) concentrations below permissible limits. Deterministic health risk assessment indicated that PBA reduced hazard index by 84.5% and lifetime carcinogenic risk (LCR) from As exposure by 88.9%. Hazard quotient for nickel (Ni) and zinc (Zn) remained acceptable for all age groups except for As in children, where LCR exceeded permissible limits. Monte Carlo simulations revealed that over 95% of individuals across age groups faced unacceptable non‐carcinogenic and carcinogenic risks from As exposure, regardless of cooking method. In conclusion, PBA effectively lowered metal concentrations and health risks, especially for toxic metals in rice. Future studies could enhance risk assessment accuracy by analysing metal bioavailability and speciation of metals particularly As.
Platform's preference information sharing in the presence of private label
Authors: Liu Xiaomin , Li Wenping 
Published: September 2024

AbstractIn recent years, platforms have launched their private labels based on valuable consumer data and efficient supply chains. At the same time, some platforms share consumers’ preference information to help manufacturers in producing suitable products. In this paper, we consider a scenario where a platform sells its private label product directly and the manufacturer sells its national brand product through the platform. This study mainly investigates the platform's preference‐sharing strategy. We find that a win–win situation between the platform and manufacturer occurs when the proportion taken by the platform is high, information accuracy is low, and adjustment cost is extremely low. Otherwise, a lose–win, win–lose, or lose–lose scenario may arise. Furthermore, when the adjustment cost is extremely high or low, information sharing can be arranged through some payments. Finally, the study demonstrates that sharing preference information can either increase or decrease consumer surplus and social welfare.
His‐bundle pacing from the right atrium: Solving pacemaker implantation challenges post‐TriClip
Authors: Onishi Yoshimi , Barengo Alberto , Fioravanti Francesco , Rampa Lorenzo , Paglino Gabriele , Della Bella Paolo 
Published: September 2024

AbstractIntroductionThis case report highlights the novel role of His‐bundle pacing (HBP) from right atrium, not just for preserving cardiac function, but also for avoiding interference with TriClip devices.Methods and ResultsA 78‐year‐old female with severe tricuspid regurgitation received two TriClip devices. Postprocedure, frequent significant sinus pauses required a pacemaker. HBP was chosen to avoid lead complications. Under local anesthesia, a His pacing lead was inserted via the axillary vein using specialized catheter. Follow‐ups over 2.5 years showed stable parameters with no complications.ConclusionHBP is effective for patients with TriClip devices, ensuring optimal cardiac function and lead stability.
Hair regrowth in alopecia areata and re‐pigmentation in vitiligo in response to treatment: Commonalities and differences
Authors: Yamaguchi Hiroki L. , Yamaguchi Yuji , Peeva Elena 
Published: September 2024

AbstractBoth alopecia areata (AA) and vitiligo share common pathogenesis involving, interferon‐γ (IFN‐γ) and interleukin‐15 (IL‐15) signalling pathways that activate cytotoxic CD8+ T lymphocytes. These shared mechanisms may explain why both diseases respond to currently available treatments (e.g. topical/systemic corticosteroid) and emerging treatment modalities. As compared with the speed of re‐pigmentation in vitiligo lesions, the regeneration of pigmented terminal hair follicles in AA lesions appears fast in response to treatments targeting the inhibition of the Janus kinases (JAKs) and other kinases. We summarize the commonalities and differences between AA and vitiligo focusing on the treatment modalities, followed by recent findings associated with hair follicle stem cells (HFSC) in hair bulge (HBg) and melanocyte stem cells (McSC) in HBg and hair germ (HGm). We then discuss how HFSC and HGm‐McSC are involved in the initiation of anagen phase, followed by pigmented terminal hair regrowth in the recovering AA lesions in association with immunology. We also discuss how HBg‐McSC contribute to the migration of fully dendritic mature melanocytes into interfollicular epidermis and the equal distribution of melanin in recovering vitiligo lesions. Finally, we present four hypotheses to elucidate the delayed distribution of melanin by mature melanocytes in depigmented vitiligo lesions from the aspects of stem cell biology, as compared with quick hair recovery in AA: (1) McSC are less abundant than HFSC. (2) McSC require a long travel, whereas HFSC reside close to hair regeneration trigger point. (3) Keratinocyte scaffold to accept melanin is not well preserved, whereas scaffold for hair regrowth is well preserved. (4) Inhibitors targeting JAKs and other kinases have less direct effects on melanocyte proliferation and differentiation in vitiligo than hair regrowth in AA. Our review provides an overview of treatment modalities and bridges the gap between scientific advancement and clinical practice in AA and vitiligo management.
Dietetic research involvement is associated with the European region where a dietitian is working and their highest degree qualification
Authors: Eglseer Doris , Joossens Sofie B. A. , Kontogianni Meropi D. , O'Reilly Sharleen L. ,   EFAD Research and Evidence Based Practice Committee
Published: September 2024

AbstractBackgroundResearch is the foundation of the dietetic profession and of evidence‐based guidelines/practice. The present study aimed to examine the level of research involvement among dietitians in Europe.MethodsA cross‐sectional study was conducted among dietitians across Europe using the validated Research Involvement Questionnaire (RIQ), which assigns participants to four levels of research involvement. The survey link was distributed through various channels; for example, National Dietetic Association (NDA) members of European Federation of the Associations of Dietitians (EFAD), the EFAD eNewsletter, national newsletters, etc. Data were analysed with SPSS, using descriptive statistics, statistical tests and ordinal logistic regression analysis with the level of research involvement as the dependent variable.ResultsIn total, 257 European dietitians completed the survey (84.6% female). Most participants held a Master's degree (46.1%), followed by a Bachelor's degree (27.3%) or Doctorate (25.7%). One‐third of participants were involved at level 3 or 4 (leading research, leadership in research), whereas most were involved at level 1 (evidence‐based practice) or 2 (collaboration in research). The multivariate regression analysis showed that dietitians' research involvement was higher in dietitians with a Doctorate and in Northern/Southern Europe compared to Eastern/Western Europe.ConclusionsDietitians have low levels of research involvement in practice even when highly qualified. Interventions to motivate dietitians to be more involved in research projects are important, as well as interventions to facilitate dietitians' research activities. This would inform the discipline's evidence base, strengthen the professional status of dietitians and increase their reputation within the healthcare sector.
The opportunities and limits of open science for LGBTIQ+ research
Authors: Leskinen Emily A. , Horne Sharon G. , Ryan William S. , van der Toorn Jojanneke 
Published: September 2024

AbstractThe open science (OS) movement has the potential to fundamentally shape how researchers conduct research and distribute findings. However, the implications for research on lesbian, gay, bisexual, trans, intersex, and queer/questioning (LGBTIQ+) experiences present unique considerations. In this paper, included in the special issue on Reimagining LGBTIQ+ Research, we explore how the OS movement broadens access to and comprehension of LGBTIQ+ experiences while simultaneously imposing limitations on the representation of these identities and raising concerns about risks to LGBTIQ+ researchers and participants. Our research focuses on three facets of the OS movement. First, we examine practices related to open data, which advocates that data should be accessible to other researchers to analyze. Yet, providing access to such data challenges may compromise trust between the research team and study participants. Second, we examine practices related to open replicable research, particularly as it has the potential to both highlight and erase the experiences of groups within the LGBTIQ+ community. Finally, we consider how open access, making scholarly articles free to the public, may help educate a broader audience on the lived experiences of LGBTIQ+ people, but in regions where these identities remain heavily stigmatized and/or criminalized, access may be blocked or individuals could be penalized for retrieving this information.
A stomate by any other name? The open question of hornwort gametophytic pores, their homology, and implications for the evolution of stomates
Authors: Fortin James Paul , Friedman William E. 
Published: September 2024

SummaryAdvances in bryophyte genomics and the phylogenetic recovery of hornworts, mosses, and liverworts as a clade have spurred considerable recent interest in character evolution among early embryophytes. Discussion of stomatal evolution, however, has been incomplete; the result of the neglect of certain potential stomate homologues, namely the two‐celled epidermal gametophytic pores of hornworts (typically referred to as ‘mucilage clefts’). Confusion over the potential homology of these structures is the consequence of a relatively recent consensus that hornwort gametophytic pores (‘HGPs’ – our term) are not homologous to stomates. We explore the occurrence and diverse functions of stomates throughout the evolutionary history and diversity of extinct and extant embryophytes. We then address arguments for and against homology between known sporophyte‐ and gametophyte‐borne stomates and HGPs and conclude that there is little to no evidence that contradicts the hypothesis of homology. We propose that ‘intergenerational heterotopy’ might well account for the novel expression of stomates in gametophytes of hornworts, if stomates first evolved in the sporophyte generation of embryophytes. We then explore phylogenetically based hypotheses for the evolution of stomates in both the gametophyte and sporophyte generations of early lineages of embryophytes.
Unravelling drivers of local adaptation through evolutionary functional–structural plant modelling
Authors: de Vries Jorad , Fior Simone , Pålsson Aksel , Widmer Alex , Alexander Jake M. 
Published: September 2024

Summary

Local adaptation to contrasting environmental conditions along environmental gradients is a widespread phenomenon in plant populations, yet we lack a mechanistic understanding of how individual agents of selection contribute to this evolutionary process.

Here, we developed a novel evolutionary functional–structural plant (E‐FSP) model that recreates local adaptation of virtual plants along an environmental gradient. First, we validate the model by testing if it can reproduce two elevational ecotypes of Dianthus carthusianorum occurring in the Swiss Alps. Second, we use the E‐FSP model to disentangle the relative contribution of abiotic (temperature) and biotic (competition and pollination) selection pressures to elevational adaptation in D. carthusianorum.

Our results suggest that elevational adaptation in D. carthusianorum is predominantly driven by the abiotic environment. The model reproduced the qualitative differences between the elevational ecotypes in two phenological (germination and flowering time) and one morphological trait (stalk height), as well as qualitative differences in four performance variables that emerge from G × E interactions (flowering time, number of stalks, rosette area and seed production).

Our approach shows how E‐FSP models incorporating physiological, ecological and evolutionary mechanisms can be used in combination with experiments to examine hypotheses about patterns of adaptation observed in the field.
Variation of chin morphology and mandibular incisor length in different facial divergence patterns: New insights from CBCT records
Authors: Ghafari Joseph G. , Ziade Eliane G. , Kassab Ammar , Saadeh Maria , Macari Anthony T. 
Published: September 2024

AbstractAimEvaluate constitutional differences in chin morphology and volume, and mandibular tooth size, between different facial divergence patterns.Materials and MethodsThe sample consisted of 284 pretreatment cone beam computed tomography (CBCT) images of growing and non‐growing patients who were stratified into 4 groups based on mandibular plane inclination to cranial base (SN) angle. Linear and angular measurements were made on the lateral CBCT images: mandibular lateral incisor crown (I‐C) total (I‐A) lengths, the distances between point D (centre of symphysis) and both incisor apex (D‐A) and menton (D‐Me) and between cemento‐enamel junction and menton (CEJ‐Me); chin width at the level of the central incisor apex (CWA) and point D (CWD); and the angles of the anterior and posterior symphyseal slopes. The volume of the symphysis was measured using a specialized 3D imaging software. Group differences and associations between parameters were gauged through the three‐way ANOVA analysis.ResultsI‐C, I‐A, D‐A, D‐Me and CEJ‐Me were greater in the hyperdivergent group (p < .001). CWA and CWD were wider in the hypodivergent group (p = .003). Volume of the chin and inter‐slope angles were similar in all groups (p > .05). The anterior slope angle decreased with hyperdivegence (p < .005) in opposite pattern to the posterior slope angle (p < .005).ConclusionsShape differences in mandibular symphysis were observed between opposite divergence patterns. Mandibular incisors were longer with hyperdivergence and shorter with hypodivergence. However, chin volumes were similar across divergence groups. These findings underline the role of genetic and environmental factors that impact facial growth.
Low‐energy differential target multiplexed SCS derivative reduces pain and improves quality of life through 12 months in patients with chronic back and/or leg pain
Authors: Peacock Jeffery , Provenzano David , Fishman Michael , Amirdelfan Kasra , Bromberg Todd , Schmidt Todd , White Thomas , Grewal Prabhdeep , Justiz Rafael , Calodney Aaron , El‐Naggar Amr , Shah Binit , Esposito Michael , Gatzinsky Kliment , Kallewaard Jan Willem , Poree Lawrence , Cleland Andrew , Rice Calysta , Theis Erin , Noel Kate , LaRue Maddie 
Published: September 2024

AbstractIntroductionEnergy‐reducing spinal cord stimulation (SCS) approaches have the potential to impact patient experience with rechargeable and non‐rechargeable SCS devices through reducing device recharge time or enhancing device longevity. This prospective, multi‐center study evaluated the safety, effectiveness, and actual energy usage of differential target multiplexed (DTM) endurance therapy, a reduced energy DTM SCS derivative.MethodsSubjects who reported an overall pain visual analog score (VAS) of ≥6/10 cm and an Oswestry Disability Index score of 21–80 out of 100 at baseline with moderate to severe chronic, intractable back and/or leg pain were eligible. Evaluation visits occurred at 1, 3, 6, and 12 months post‐device activation. The primary objective was to characterize change in overall pain intensity, as measured by VAS, from baseline to 3‐month visit.ResultsFifty‐seven subjects enrolled at 12 US sites from November 2020 through June 2021, 35 were implanted with a rechargeable SCS device, and 27 completed the 12‐month visit. Subjects experienced a 50.4% mean reduction in overall pain from baseline at the 3‐month follow‐up that was sustained through 12 months. Additional outcomes including changes in overall, back, and leg pain intensity, quality of life, disability, therapy satisfaction, safety, and current battery usage are shown through 12‐month follow‐up.ConclusionThe use of DTM endurance SCS therapy in this study resulted in reductions in pain relief through 12 months, demonstrating that energy‐reducing stimulation patterns can provide clinical benefit. Clinically effective, reduced energy SCS derivatives have the potential to impact patient experience through either reduced recharge requirements or increased device longevity.
10. Complex regional pain syndrome
Authors: van der Spek Daniël P. C. , Dirckx Maaike , Mangnus Thomas J. P. , Cohen Steven P. , Huygen Frank J. P. M. 
Published: September 2024

AbstractIntroductionComplex regional pain syndrome (CRPS) is a clinical disorder that can develop following surgery or trauma. Based on the most prominent underlying pathophysiological mechanisms, CRPS can be classified into different subtypes, namely inflammatory, nociplastic/neuropathic, vasomotor, and motor. Depending on the subtype, personalized treatment can be applied. If conservative treatments are insufficient or ineffective, more invasive treatments may be recommended. This article provides an overview of the most recent insights into CRPS and discusses the most common invasive treatments.MethodsThe literature regarding interventional treatments for CRPS has been systematically reviewed and summarized.ResultsBisphosphonates are effective in treating the inflammatory subtype, while ketamine can provide pain relief for the nociplastic/neuropathic subtype. Sympathetic blocks are effective in addressing vasomotor disturbances. For patients with refractory symptoms, neurostimulation is a viable option due to its multimechanistic properties for all subtypes. End‐of‐line motor disturbances may benefit from intrathecal baclofen.ConclusionsCRPS is a debilitating condition with an unpredictable course. The effectiveness of treatment varies from patient to patient. When conservative approaches prove insufficient, gradual progression to invasive treatments based on the underlying subtype is recommended.
Recalcitrant extensive dermatophytosis in twin brothers with APECED syndrome
Authors: Najeeb Aysha , Gaurav Vishal , Dudani Pankhuri , Das Shukla , Gupta Somesh 
Published: September 2024

AbstractChronic mucocutaneous candidiasis (CMC) is characterized by recurrent infections with Candida spp., often linked to primary immunodeficiencies. We report a case of two 8‐year‐old monozygotic twin brothers presenting with extensive dermatophytosis, later diagnosed with autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy (APECED) syndrome due to a homozygous p.M1V mutation in the AIRE gene. The twins exhibited widespread skin and nail infection, along with malabsorption, dental caries, and other autoimmune manifestations. This case highlights the novel presentation of extensive dermatophytosis in APECED, underscoring the variability in clinical expression even within a single family.
Further evidence for endozoochory in a mycoheterotrophic orchid Cyrtosia septentrionalis: seed dispersal by the masked palm civet Paguma larvata
Authors: Suetsugu K. 
Published: September 2024

Abstract
Cyrtosia septentrionalis, an orchid species, is notable for its sausage‐shaped red fleshy fruits, which can reach up to 10 cm in length. Previous research identified frugivorous and omnivorous birds, especially the brown‐eared bulbul Hypsipetes amaurotis (Pycnonotidae, Passeriformes), as key seed dispersers of C. septentrionalis in natural habitats. This finding challenges conventional belief that orchid seeds are primarily wind‐dispersed. Moreover, given the rarity of specialized co‐evolutionary relationships between fruits and frugivores, C. septentrionalis may also rely on mammals for seed dispersal in certain regions.
We aimed to explore the fruit consumption habits of animals other than birds. Motion sensor‐equipped cameras were used to observe interactions with the fruits of C. septentrionalis and assess the viability of seeds post‐consumption.
The observations revealed three animal species consuming the fruits, with the masked palm civet Paguma larvata (Viverridae, Carnivora) identified as a dominant consumer in the investigated population. Microscopy analysis of seeds retrieved from P. larvata faeces indicated that the seeds remained intact and viable after passing through the digestive system of this carnivorous mammal.
The above discovery suggests a potential role for carnivorous mammals in seed dispersal of C. septentrionalis, alongside birds, thus broadening our understanding of the complex seed dispersal strategies employed by orchids.