bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decommissioning Using Reverse Reeling
Authors: Ripley A. , Roux A. , Young S. 
Published: October 2024

With numerous offshore facilities coming to the end of their operational life cycle, operators are looking at options to extend the life of their aging assets or where no viable alternative exists, complete decommissioning of the field. Decommissioning in Australia involves the removal of all surface and subsurface infrastructure used to support the oil and gas industry and is a requirement under the Offshore Petroleum and Greenhouse Gas Storage Act 2006, where titleholders are responsible for the full costs and safe removal of all offshore infrastructure, (NOPSEMA, 2020).
It is estimated that over the next few decades the majority of the oil and gas fields in Australia will be decommissioned and to align with the legislative act, operators are already taking steps to understand and address the decommissioning costs, requirements and methodologies, and in some instances have already started the process of retiring and removing their facilities.
The scale of the challenge is vast, the Centre of Decommissioning Australia, (CODA, 2020) has conducted a review on behalf of a number of the Australian operators and reported that in Australia alone, 6660km of export and infield pipelines and 1500km of umbilicals, excluding spools, flexible jumpers, risers, flying leads etc. have been installed and will be required to be removed or left in-situ with the agreement of the Australian legislative body, NOPSEMA. The cost associated with the decommissioning of the offshore assets is significant with government estimates of up to $60bn AUD, (Wood Mackenzie, 2020).
A Game Changer: Initiating a Massive Movement of Permanent Magnet Motor Application for Electric Submersible Pump Design in Remote Area Operation, Sangasanga Oil Field Indonesia
Authors: Ridlah Muhammad Rasyid , Amal Panji Ikhlasul , Hidayat Teguh Rachman , Almadani Nadir Faisal , Wijaya I. Pandu , Lobanov Andrei , Maltsev A. , Minniakhmetov Nail 
Published: October 2024

Abstract
The application of electric submersible pumps by transforming kinetic energy into boosting pressure is widely recognized in optimizing well performance. However, it becomes challenging under remote area operations due to limited electric power supply resources. Power supply failures result in additional pump maintenance, thus shortening ESP run life and increasing operational costs eventually. This paper will introduce a solution to this challenge, i.e., innovative permanent magnet motor technology (PMM), and present successful PMM applications in the ESP system to reduce power consumption and prevent ESP failure in a mature oil field in Sangasanga, Indonesia. Permanent magnet motor (PMM) technology is designed with magnetic material and unique apparatus for in-situ re-magnetize to generate a constant rotor magnetic field, thus resulting in greater torque and maximum pump rotation and ultimately reducing the power consumption. In addition, it works under high downhole temperatures of up to 480F without de-magnetization risk. In a three-year study, ESP design with PMM technology was implemented in several oil wells. ESP performance is evaluated and compared by parameters, i.e., annual power consumption, ESP run life, and production sustainability. The parameters are presented for three different case studies which compare three production wells equipped with conventional asynchronous ESP motors (AM) and PPM motor. The campaign for PMM installation was started in 2019. Now, 40 % of ESP wells in the Sangasanga field have been equipped with PMM. With conventional AM motors, the average power consumption for ESPs is around 117,582 kWh a year. The number decreases by about 24-30% with PMM. Meanwhile, the operating cost decreases linearly accordingly. Moreover, the installation of PMM shows a promising result in securing production sustainability since it prevents unplanned shutdowns due to power shortages. As a result, the improvement has delivered an additional value of about $ 111,650 for each well annually. In addition, compared to the conventional AM motor, ESP's run life has increased from 3.5 years to 4 years by using PMM. The decrease in electricity usage also creates a domino effect on carbon emissions for better environmental sustainability.
Trend Analysis for Calibrated Active System Volume and Differential Flow Significantly Reduces False Positive Kick Alarm During Drilling
Authors: Ding Danhong , Mei Yunyi , Ge Su , Yong Fengwei , Lu Yaozhong , Ge Yunhua 
Published: October 2024

Abstract
Rapid kick detection is an essential part of rig safety. Identifying potential kick events in time is valuable and is an urgent and critical task for rig personnel and remote Operation Support Center(OSC) users. A new monitoring system has been developed by firstly calibrating the active system volume for pipe and cuttings displacement during drilling and then by detecting a statistically significant trend in the observed data rather than to rely solely on absolute values and threshold crossing to maximize the sensitivity whilst minimizing the number of false alarms.
More than hundreds of historical kick alarms were reviewed and the corresponding mud logging data before the events occurred were displayed in log format against time for clear identification of anomalies in three different tracks: one track for pit volume, one for flow-in and flow-out, the third hole depth, bit depth and block position. By applying an automated rule-based system, the states of rig activities are also displayed simultaneously by detection of bit movement, pump, rotation status and other elements. It is noticed that the data absolute value, data noise, and rig operations such as sudden string movements and flow transients has significant interference to the detection of kick event and that the differential flow is more sensitive early kick indicator than pit volume in most of the historical cases.
A pit volume calibrated for drill pipe and cuttings displacement during drilling and a trend analysis by applying Page-Hinkley method for monitoring both active system volumes and differential flows are established and the monitoring system is updated. The system has been tested and refined with the data flows of the historical cases in labs to maximize the sensitivity whilst minimizing the number of false alarms. A significant reduction of false positive alarms is achieved by reducing triggering of 1-2 alarms per well per week while maintaining a 100% true positive identification rate by comparing 1-2 alarms per day per well in the old system which was relied solely on absolute values and threshold crossing.
This paper summarizes the current methods for the detection of kick event, the study and the findings from replay of historical kick alarm cases, the methods of calibrating pit volume during drilling operation, the algorithms for rig state detection, and the application of early kick detection methods of differential flow and flow-back fingerprint.
Having Sexual Partners Lowers the Risk of Glaucoma-A Mendelian Randomization Study
Authors: Zhuang hua , Zhang Wu-Zhen 
Published: October 2024

Abstract

Objectives: Previous paper suggested that engaging in sexual activity exacerbated glaucoma symptoms. However, we challenge this viewpoint and designed this Mendelian randomization(MR) study to uncover the truth.
Methods: To investigate the causal relationship between the two, this experiment utilized single nucleotide polymorphism(SNPs) related to "lifetime number of sexual partners" (LNSP) from the United Kingdom Biobank (UKB) and SNPs associated with glaucoma from the FinnGen Database. There were a total of 63 SNPs highly correlated with LNSP at the genome-wide significant level, which were merged with glaucoma-related SNPs. After removing their palindromic sequences, MR was conducted using the TwoSample-MR R package. Additionally, tests for heterogeneity and pleiotropy were performed using R programming.
Results: In the glaucoma group, MR analysis showed: inverse variance weighted(IVW)(OR=0.758, P=0.030), MR Egger(OR=0.654,P=0.475), simple mode (OR=0.854,P=0.657), weighted median (OR=0.819, P=0.221) and weighted mode(OR=0.803,P=0.501). In the primary open angle glaucoma (POAG) group, the result showed: IVW(OR=0.897,P=0.570), MR Egger(OR=0.425, P=0.335), simple mode(OR=1.659, P=0.412), weighted median(OR=1.052, P=0.855) and weighted mode(OR=1.464,P=0.533). Heterogeneity and pleiotropy were not detected in either group. The funnel plots for both groups were relatively symmetrical.
Conclusion: We reveal the truth that having sexual partners not only does not increase the overall incidence of glaucoma but, conversely, also lowers its incidence. Therefore, glaucoma patients should pursue a fulfilling sexual life with your partners with peace of mind.
Cross-species transcriptome analysis of the subthalamic and para-subthalamic nuclei reveal mRNA patterns unique to primate and relevant to neuropsychiatry
Authors: Dumas Sylvie , Ricci Alessia , Rubino Eleonora , Rosenkilde Marie Biviano , Francois Chantal , Karachi Carine , Wallen-Mackenzie Åsa 
Published: October 2024

Abstract

The ventromedial subthalamic nucleus (STN) is associated with affective function via limbic brain networks. Clinical data indicate the anterior aspect of ventromedial STN as an important target in Deep brain stimulation (DBS) intervention of psychiatric disorder, including Obsessive-compulsive disorder (OCD), for which Selective serotonin reuptake inhibitors (SSRIs) are prescribed. However, far from all patients respond to either SSRIs or DBS. Despite clinical relevance, the primate STN is lacking in molecular and anatomical detail. Here, transcriptome data generated in mice was implemented in comparative analysis with macaque and human. Remarkable species differences were observed. Serotonin receptor 2c (HTR2C) mRNA was identified in a distinct ventromedial STN profile in macaque and human, non-paralleled in mouse. This included the medial tip and anteromedial STN, where HTR2C was distributed in patterns matching reports of serotonergic innervation. In primates, but not mice, a previously undescribed far-anterior STN brain area was uncovered, and the anterior, but not posterior, STN was found to border the hypothalamic para-STN. In both mice and primates, gradients of HTR2C mRNA allowed para-STN to be subdivided into core and shell domains. Dorsal to STN, para-STN was partly embedded in the Medial forebrain bundle (MFB), a DBS target in OCD and depression. Transcriptome data visualized in serial sections and 3D brain fly-through videos challenge current atlases of STN, pSTN, and MFB anatomy in mice and primates. Differential mRNA patterns in the primate, including unique HTR2C profiles, may provide openings for drug discovery and enhanced anatomical precision, and uncover neurobiological underpinnings of psychiatric disorders.
Keratinocyte-Driven Dermal Collagen Formation in the Axolotl skin
Authors: Satoh Akira , Ohashi Ayaka , Sakamoto Hirotaka , Kuroda Junpei , Kondo Yohei , Kamei Yasuhiro , Nonaka Shigenori , Furukawa Saya , Yamamoto Sakiya 
Published: October 2024

Abstract

Type I collagen is a major component of the dermis and is formed by dermal fibroblasts. The development of dermal collagen structures has not been fully elucidated despite the major presence and importance of the dermis. This Lack of understanding is due in part to the opacity of mammalian skin and it has been an obstacle to cosmetic and medical developments. We succeeded in revealing the process of dermal collagen formation using the highly transparent skin of the axolotl and fluorescent collagen probes. We clarified that epidermal cells, not dermal fibroblasts, primarily contribute to dermal collagen formation. Fibroblasts play a role in modifying the collagen fibers already built by keratinocytes. We confirmed that collagen production by keratinocytes is a widely conserved mechanism in other model organisms. Our findings demand the current consensus about dermal collagen formation to change and lead to innovations in cosmetology and skin medication.
Perpetrating-Suffering Intimate Violence: Self-Harm-Suicide Thoughts and Behaviors, Mental Health, and Alcohol Use among Mexican Youth during COVID-19
Authors: Chainé Silvia Morales , Bacigalupe Gonzalo , García Rebeca Robles , López-Fuentes Alma Luisa , Romero Violeta Félix 
Published: October 2024

Abstract

Background
The COVID-19 epidemic had a deleterious impact on mental health and substance abuse as well as an increase in several forms of violence including self-harm, and interpersonal violence, among youth from low- and middle-income countries. However, the relationship among these variables and its directionality have not been established. The study describes the trends and relationship directionality between these variables among young adults during the COVID-19 pandemic in Mexico.
Methods
This longitudinal cohort study comprises an evolving group of young Mexican adults: 1,390 participants aged 18 in 2021, 654 aged 19 in 2022, and 442 aged 20 in 2023. Proportions by sex—50% were matched in every cohort, and the evolution-age sample accomplishment accounted for 47% in 2022 and 32% in 2023.
Results
According to a structural equation model, which fit the data from 195 iterations with 246 parameters (X² [2,722] = 8,327.33, p < 0.001), yielding a CFI of 0.946, a TLI of 0.943, and an RMSEA of 0.029 [0.028–0.029]), perpetrating intimate violence, preceded by suffering intimate violence, combined with suffering anxiety symptoms, was associated with self-harm suicide thoughts and behaviors (ShSTB), marked distress, dysfunction, and somatization symptoms. The relationship was stronger in women and 20-year-old Mexicans. In men, this pathway was exclusively associated with ShSTB. Suffering from intimate violence has been associated with depression, anxiety, and PTSD symptoms, as well as harmful alcohol use.
Conclusion
During an epidemic, prevention programs should be designed to warn about self-harm-suicide thoughts and behavior, not only to ensure the safety of the victims of intimate-personal-violence victim but also to prevent the suicidal behavior of perpetrators.
Effect of duration of ECMO application on prolonged mechanical ventilation after lung transplantation in patients with idiopathic pulmonary fibrosis
Authors: Tian Jing , Jin Ke , Wang Song , Zhang Jingyu , Cui Lan , Xu Hongyang 
Published: October 2024

Abstract

Background Lung transplantation is the optimal treatment choice, while extracorporeal membrane oxygenation (ECMO) provides cardiopulmonary support during the perioperative period of lung transplantation. Currently, there is no reported research on the ECMO withdrawal and duration of mechanical ventilation in idiopathic pulmonary fibrosis (IPF) patients undergoing lung transplantation. Therefore, this study aims to evaluate the impact of ECMO duration on prolonged mechanical ventilation (MV) time in patients, attempting to explore the relationship between the two. Methods This study included 170 patients with IPF who underwent lung transplantation under ECMO technology. The patients were divided into normal and delayed groups based on the ECMO application time of 72 hours. A multifactor logistic regression analysis was conducted to explore the independent risk factors for prolonged mechanical ventilation time (more than 3 days), and restricted cubic spline was used to investigate the relationship between ECMO application time and MV time. Receiver operating characteristic (ROC) was further utilized to assess the performance of ECMO application time in predicting prolonged mechanical ventilation time for patients. Results The gender and ECMO application time of patients with IPF are independent risk factors for prolonged MV time. In post-lung transplant patients, for each additional hour of ECMO application time, the risk of MV exceeding 3 days increases by 0.15 times. A restrictive cubic spline plot of ECMO application time and MV time shows a nonlinear relationship between the two groups, with an area under the ROC curve of 0.854 (95% CI 0.796–0.913, P < 0.05). Conclusion After lung transplantation, there is a nonlinear relationship between the application time of ECMO and MV time in patients with IPF. The application time of ECMO can predict well the extension of MV in patients during ICU stay. Therefore, clinicians can assess the duration of MV in patients with IPF based on the application time of ECMO, further avoiding complications related to MV.
Laparoscopic right adrenalectomy: Is it necessary to use liver retraction trocar?
Authors: Soltani Mohammad Hossein , Hassani Hamed , Jadidi Sajedeh , Narouie Behzad , Darzi Mohammad Mehdi , Jowzi Ali , Dadpour Mehdi 
Published: October 2024

Abstract

Background and aims:
We aimed to evaluate the surgical outcomes and complications in patients who underwent right laparoscopic adrenalectomy (RLA) with or without using a liver retractor trocar.
Materials and Methods
In this cohort study, all patients who were candidates for RLA were included. One surgeon did not use a liver retractor at all while it was used by the others. All the pre-operative, peri-operative and surgical complications including hospitalization, surgical duration, Hb drop and pack cell injection, conversion to open surgery, and ICU admission were compared between the two groups.
Results
A total of 228 patients were included in this study: 60 patients in the group without liver retraction and 168 patients in the group with liver retraction. There were no differences in pre-operative data including sex (p = 0.740), history of surgery (p = 0.618), age (0.682), BMI (0.864), risk of anesthesia (p = 0.418), and tumor size (p = 0.218) between two groups. There were also no significant differences in peri-operative data and surgical complications including pack cells injection (p = 0.882), re-hospitalization (0.682), conversion of procedure to open surgery (p = 0.990), ICU admission (p = 0.782), hemoglobin drop (p = 0.662), surgical duration (p = 0.188), hospitalization duration (p = 0.062) and pathology report (0.916) between the two groups
Conclusion
According to the results of this study, the use or non-use of liver retraction in laparoscopic right adrenalectomy by an expert surgeon has no significant impact on peri-operative and post-operative outcomes and surgical complications. We do not recommend the routine use of a liver retractor trocar for this surgery, but only when the surgeon feels the need for it intraoperatively, which is rare in experienced surgeons.
The landscape of the bacteriome and mycobiome at different stages of root caries and the cross-kingdom interactions of the core species
Authors: Ji Mengzhen , Xiong Kaixin , Fu Di , Chi Yaqi , Wang Ye , Yao Lin , Yang Xueqin , Yan Yujia , Zhu Hualing , Li Yanyao , Ren Biao , Zou Ling 
Published: October 2024

Abstract

Background
The unbalanced oral microbiome is considered the key pathogenic agent for root caries, the most common tooth disease in elderly individuals; however, the bacteriome and mycobiome at different stages of root caries, especially from the same individual, are not clear.
Results
In this study, superficial and deep root caries plaques from thirty patients with different levels of root caries simultaneously in the oral cavity were collected, whereas sound root surface plaques from their healthy teeth served as caries-free controls. The full-length sequencing results of 16S and 18S rDNA analysis via the self-controlled method on the basis of the same patients indicated that the different stages of root caries represented different microbiota, including Streptococcus mutans and Actinomyces sp. HMT448 in superficial root caries and Prevotella sp. in deep root caries. Candida albicans was the most abundant fungal species from all the plaques, while it showed strong interspecies interactions with S. mutans and Actinomyces sp. Their interactions were closely associated with the different stages of root caries. An in vitro model further confirmed that C. albicans was able to increase the growth, biofilm formation and cariogenicity of S. mutans and A. viscosus through the activation of the arginine biosynthesis pathway, indicating its key roles in the development of root caries.
Conclusion
Our study revealed the first landscape of the microbiome from different stages of root caries and indicated that targeting the interactions of core species may be a practical way to prevent and treat clinical root caries.
Multi-resistant ST 258 Klebsiella pneumoniae presenting a hypermucoviscous phenotype
Authors: Souza Alessandra Beatriz dos Santos Rondon , Pinheiro Felipe Ramos , Dávila Alberto Martín Rivera , Chagas Thiago Pavoni Gomes , Penna Bruno de Araújo , Pereira Renata Freire Alves , Aguiar-Alves Fábio 
Published: October 2024

Abstract

To characterize phenotypically and genotypically a strain of Klebsiella pneumoniae ST258 isolated from an immunosuppressed patient treated at a University Hospital in Brazil, it was performed Antimicrobial Susceptibility Testing, Analysis of the Ability to form Biofilm, Genome Sequencing and String Test. The sample was characterized as a non-biofilm-forming, multi-resistant and hypermucoviscous strain. Genomic analysis revealed the presence of resistance genes, virulence genes and plasmids. This is the first report of hypervirulent hypermucoviscous KPC ST258 in Rio de Janeiro, Brazil. KPC ST258 represents a significant global health threat due to the limited available treatment to fight these infections. This observation poses a threat to the community and hospital environments, highlighting the need for increased surveillance to detect these strains.
Multi-parametric MRI combined with radiomics for the diagnosis and grading of endometrial fibrosis
Authors: Wang Huanhuan , Zhu Li , Zhu Hui , Meng Jie , Liang Huanhuan , Li Danyan , Hu Yali , Zhou Zhengyang 
Published: October 2024

Abstract

Background Accurate evaluation of endometrial fibrosis can help clinicians schedule individual treatment. This study aims to explore the application value of multi-parametric MRI (MP-MRI) combined with radiomics in the diagnosis and grading of endometrial fibrosis, aiming to construct models that can effectively distinguish endometrial fibrosis and compare the diagnostic performance of radiomics models established by different machine learning algorithms. Methods A total of 74 patients with severe endometrial fibrosis(SEF), 41 patients with mild to moderate fibrosis (MMEF)confirmed by hysteroscopy, and 40 healthy women of reproductive age were prospectively enrolled. All participants underwent T2 and DWI sequence scans during the periovulatory period. By freely delineating the volume of interest (VOI) of the endometrium in three subgroups, radiomic features were extracted and selected. Two feature selection methods and four machine learning classifiers were combined in pairs to establish five prediction models [model1 (T2 + ADC + clinical data), model2 (T2 + ADC), model3 (T2), model4 (ADC), and model5 (clinical data)], resulting in a total of 40 classification models. The predictive performance of all models was evaluated using the area under the curve (AUC), F1 score, and accuracy (ACC). Results Among the 40 classification models, the "UFS-LR" model, which combined unsupervised feature selection (UFS) with the logistic regression (LR) classifier, performed the best, with an average AUC of 0.92 on the test set. Among the five models constructed via UFS-LR, model1 exhibited the best performance, with average AUC, F1 score, and ACC values of 0.92, 0.79, and 0.81, respectively. The T2-related models had higher average AUC values than model4 and model5 did, especially in the MMEF and SEF groups. Among the optimal features selected from different models, T2-related features accounted for the largest number and had the highest weight. Conclusions Machine learning-based MP-MRI radiomics analysis exhibited excellent performance in grading endometrial fibrosis and has great potential for providing robust support for clinical diagnosis and treatment.