bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clarification of Microvibration Nature Measured by Vibraimage Technology. Part 1
Authors: А.А. Косенков 
Published: October 2024

Особенностью устоявшейся практики видеосъёмки в процессе получения параметров виброизображения (ВИ) является учёт всех колебаний головы, попавших в объектив веб-камеры, которые можно разделить на 2 информационных потока: 1) колебания головы как единого целого объекта по отношению к фону преимущественно во фронтальной плоскости (поток 1); 2) внутренние колебания одних частей лица относительно других в границах внешнего контура головы, включая, возможно, мимические движения, моргания, движения глаз, движения мягких тканей, обусловленные сердечными сокращениями и движением крови по крупным сосудам или пульсацию поверхностных сосудов, а также колебания волос на голове (поток 2). Применение маски из папье-маше, полностью закрывавшей лицо в сочетании с трикотажной шапкой позволило устранить влияние потока 2. Таким образом, для анализа был оставлен только поток информации, представленный внешними колебаниями головы. Сравнение основных параметров, полученных при регистрации ВИ в маске и без маски, показало статистически значимые различия. При надетой маске значения поведенческих параметров, которые автор метода В. А. Минкин относит к позитивным, имели существенную тенденцию к увеличению, а негативных параметров — к снижению.
The feature of the established practice of vibraimage (VI) parameters processing is the consideration of all head vibrations captured by webcam, which can be divided into 2 information streams: 1) vibrations of the head as a single object in relation to the background, mainly in the frontal plane (stream 1); 2) internal vibrations some parts of the face relative to others inside the external contour of the head, including, possibly, facial movements, blinking, eye movements, movements of soft tissues caused by heart contractions and the movement of Уточнение природы колебаний, измеряемых посредством технологии виброизображения. Часть 1 159 blood through large vessels or pulsation of superficial vessels as well as vibrations of hair (stream 2). The use of a papier-mâché mask that completely covered the face in combination with a knitted hat made it possible to eliminate the influence of flow 2. Thus, only stream 1 represented by external vibrations of the head was left for analysis. A comparison of the main vibraimage parameters measured with and without the mask showed statistically significant differences for some vibraimage parameters. Measured with the mask the values of behavioral parameters, which vibraimage technology developer — V. A. Minkin classifies as positive, had a significant tendency to increase, and negative parameters — to decrease.
БАЗЫ ДАННЫХ МИНУТНЫХ ЗНАЧЕНИЙ НЕПРЕРЫВНЫХ МОНИТОРИНГОВЫХ ГРАВИМЕТРИЧЕСКИХ НАБЛЮДЕНИЙ НА ОБСЕРВАТОРИИ «АРТИ» ЗА 2021 И 2022 ГОДЫ
Authors: А.С. Бебнев 
Published: October 2024

Приводятся комментарии к базам данных минутных значений непрерывных мониторин- говых гравиметрических наблюдений на обсерватории «Арти» за 2021 и 2022 гг.
Some comments and results on 1-minute databases of the gravity measurements at the observatory “Arti” for 2021 and 2022 are provided in this paper.
The Clinical Application of Quality Nursing Service in Urological Nursing
Authors: Yi Zuohui 
Published: October 2024

Objective: To explore and analyze the clinical application effect of high-quality nursing service in urology nursing. Methods: 400 patients who received treatment in the urology department of our hospital were selected as the study object and randomly divided into two groups. The control group and nursing group, had 200 patients in each group. The control group received the usual nursing mode, while the nursing group received high-quality nursing services. Results: Through comparative analysis, the complication rate of the nursing group was significantly lower than that of the control group, and the satisfaction rate was significantly higher. Conclusion: The application of high-quality nursing service in the nursing of urological patients is remarkable.
RESÍDUOS DO MEDIEVO: A MORTE E O MACABRO EM GIL VICENTE E ARIANO SUASSUNA
Authors: Lima Francisco Wellington Rodrigues 
Published: October 2024

O presente trabalho investigativo revisita a dramaturgia de dois grandes nomes da história do teatro mundial: o teatro medieval português vicentino (Trilogia das Barcas – do Inferno (1517), do Purgatório (1518) e da Glória (1519) –, Auto da História de Deus, Auto da Alma) e o teatro brasileiro de Ariano Suassuna (Auto da Compadecida) -, abordando os elementos significativos e relativos à morte e ao macabro. O nosso objetivo é demonstrar que há semelhanças e diferenças residuais na forma de ver, pensar e sentir a morte e o macabro no teatro vicentino e no de Suassuna; semelhanças e diferenças oriundas de povos e tempos distantes e que, independentemente do tempo e do espaço, continuaram atualizando-se e se modificando continuamente. Para tal, utilizamos os conceitos de resíduo, hibridismo, cristalização e mentalidade trabalhados pela Teoria da Residualidade sistematizada por Roberto Pontes. Para a orientação da nossa pesquisa investigativa, o método de procedimento utilizado será o comparativo. Buscaremos subsídios no corpus teórico da Literatura Comparada e os mesclaremos aos conceitos operativos da Teoria da Residualidade Literária e Cultural.
OS RESÍDUOS MEDIEVAIS DO CORPO GROTESCO EM DONA FLOR E SEUS DOIS MARIDOS, DE JORGE AMADO
Authors: Carvalhêdo Barbosa Iêda , Dias Martins Elizabeth 
Published: October 2024

Busca-se, no presente trabalho, analisar o corpo grotesco no romance de Jorge Amado, Dona Flor e seus dois maridos, no que respeita à liberdade da mulher no trato com seu corpo e na relação estabelecida entre comida e sexo na narrativa. No desejo de compreender como a mentalidade medieval acerca dessa temática manifesta-se ativamente nessa obra, nos baseamos em Baktin (2010) e na Teoria da Residualidade Literária e Cultural, proposta teórico-investigativa sistematizada por Roberto Pontes. Esta pode ser resumida no seguinte: na cultura e na literatura nada é original, tudo é residual; e faz uso dos seguintes conceitos operativos: resíduo, cristalização, mentalidade e hibridação cultural.
FORMAÇÃO LEITORA: UMA ANÁLISE DE ELEMENTOS DA POESIA INFANTIL EM POEMAS SELECIONADOS DOS PIAUIENSES CLIMÉRIO FERREIRA E MARTINS NAPOLEÃO
Authors: Moreira de Carvalho Maria do Carmo , Oliveira Lima Sara Regina 
Published: October 2024

RESUMO: A poesia infantil, como afirma Bordini (1981), sofre com os obstáculos do menosprezo às iniciativas ligadas ao estudo dessa área. A poesia de autores piauiense direcionada a criança é desfavorecida com a falta de estudos, embora aos poucos venham se estabelecendo, a investigação ainda é um tanto limitada, constitui-se por produções de pouco pesquisa no âmbito acadêmico. Tendo como base a teoria literária infantil para a fundamentação do problema, o propósito desta pesquisa é investigar a contribuição da poesia dos autores piauienses, Climério Ferreira (2008) e Martins Napoleão (2003), para a poesia para crianças, como pode ser apreciado por este público, o leitor em formação. Tem, pois, como objetivo discutir os pressupostos da poesia infantil, suas especificidades, verificar como estes textos literários são adequados para a leitura de crianças e sua atuação dentro da literatura piauiense. Pretende-se analisar poemas acessíveis ao público mencionado, considerando as peculiaridades estéticas, elementos, temáticas e formas constituintes da poética infantil, tal como a sonoridade rítmica, elementos linguísticos e formas de construção pela qual induz a interação da criança com o texto possibilitando momentos imaginativos. Um exemplo disso, é o diálogo estabelecido entre o poema Um momento, na minha cidade humilde e a cantiga de roda Ciranda, cirandinha, à medida em que Napoleão integra à temática imagética do poema características do folclore brasileiro e caracteriza-o como de origem popular, o leva a aproximar-se do universo infantil, podendo considerar-se como apropriado e aceito pelo público.
Analisis Postur Kerja Pada Karyawan Dengan Metode Rapid Office Strain Assessment (ROSA) Guna Memperbaiki Fasilitas Kerja Dengan Pendekatan Antropometri
Authors: Diana Diana , Andriani Meri , Dewiyana Dewiyana 
Published: October 2024

Bea Cukai Langsa merupakan sebuah instansi yang bertugas melaksanakan pengawasan dan pelayanan di bidang kepabeanan dan cukai. Dalam menjalankan aktivitas perusahaan tiap harinya, para karyawan kantor menggunakan komputer untuk membantu pekerjaan mereka. Setelah dilakukan observasi terhadap 15 orang karyawan merasakan keluhan nyeri pada bagian leher, bahu, punggung, dan pinggang (Musculoskeletal Disorders) Tujuan penelitian Menentukan tingkat risiko postur kerja yang dialami karyawan saat bekerja didepan komputer dan merancang fasilitas kerja untuk perbaikan fasilitas kerja. Metode yang digunakan yaitu ROSA untuk mengukur risiko yang berkaitan dengan penggunaan komputer, antropometri untuk dimensi tubuh, persentil untuk menentukan ukuran rancangan, dan simulasi catia untuk pengaplikasian hasil rancangan, dan perancangan fasilitas kerja menggunakan pendekatan antropometri. Hasil dan pembahasan terdapat 4 karyawan memiliki skor 8, 6 karyawan memiliki skor 7, 4 karyawan memiliki skor 6 artinya berisiko dan 1 karyawan memiliki skor 5 artinya tidak berbahaya. Ada 7 dimensi yang dipergunakan untuk perancangan kursi yaitu Tinggi Lutut, Pantat Poplitieal, Lebar Pinggul, Tinggi Duduk Tegak, Lebar Bahu, Tinggi Siku Duduk, Panjang Lengan Bawah dan 3 dimensi untuk perancangan meja yaitu Tinggi Siku Duduk, Jangkauan Tangan, Rentang Tangan Siku. Seluruh perhitungan mengunakan persentil 50 dengan beberapa alasan, dikarenakan hasil uji keseragaman data hampir semua seragam. Kesimpulan, tingkat risiko yang dialami 15 karyawan disebabkan dari postur duduk yang berisiko dan kurangnya kesadaran penggunaan fasilitas yang benar, maka dibutuhkan perbaikan postur kerja yang diantaranya yaitu merancang ulang kursi dan meja dengan spesifikasi ukuran dimensi tubuh karyawan menggunakan persentil 50.
Retorno salarial da experiência de migração dos empreendedores e assalariados
Authors: Orellana Vivian dos Santos Queiroz , Aragón Jorge Alberto Orellana , Rosa Samanda 
Published: October 2024

O objetivo deste artigo é investigar o diferencial de rendimento entre migrantes de retorno interestadual e não migrantes inseridos em ocupações empreendedoras ou assalariadas usando dados da Pesquisa Nacional por Amostra por Domicílios (PNAD) de 2015. Para tanto, é aplicada a decomposição detalhada de Oaxaca-Blinder e um método em dois estágios para contornar o problema de autosseleção amostral na estimação das equações de salários. Os resultados mostram que o migrante de retorno de curto e médio prazo inserido como empreendedor ganha um rendimento 19% e 17% menor do que o não migrante na mesma ocupação, respectivamente, sendo negativamente selecionado em atributos produtivos não observados. Já o remigrante assalariado de curto e médio prazo recebe um salário 62% e 49% maior do que o não migrante na mesma ocupação, respectivamente, sendo positivamente selecionado em melhores tributos produtivos não observados. O engajamento do remigrante no empreendedorismo pode ter sido motivado pornecessidade.
Natural Sciences in Secondary Education Following the Spanish Education Reform of 1970
Authors: Martínez Ruiz-Funes María José , Marín-Murcia José Pedro 
Published: October 2024

Abstract
This article deals with the study of natural sciences in non-compulsory secondary education from the end of the nineteenth century until the educational reform in 1970. We begin with a critical review of the ways in which the secondary education curriculum and textbooks of this period conveyed established knowledge about natural sciences. We then examine the evolution of natural sciences textbooks and successive editions thereof produced by different publishers in terms of their design, structure, content, and context, methods which are complemented by information concerning authorship and commercial viability. We conclude by arguing that, since textbook publishers did not undertake substantial innovations between 1970 and the mid-1980s, traditional nineteenth century natural sciences school knowledge prevailed into the 1990s.
Production Systems and Nature in Spanish Textbooks from 1965 to 1990
Authors: Canet Cecilia Valbuena , Rubio Ana María Badanelli 
Published: October 2024

Abstract
The objective of this article is to explore the relationship between concepts relating to nature and production and, by extension, to work, personal prosperity, and Spain's economic growth, as portrayed in compulsory education textbooks between 1965 and 1990. To this end, in our investigation we scrutinize the evolution of the conception and presentation of work, consumer relations, and economic relations in school curricula and in the discursive form that they ultimately took in Spanish school textbooks. In the course of the article, we identify the continuities found in school textbooks as well as the novelties that began to appear with the beginning of developmentalism in Spain.
ANALISIS PERBANDINGAN PERFORMA FHRP PADA ROUTING EIGRP MENGGUNAKAN IPV4 DAN IPV6
Authors: Wahyudi Sandi , Destya Senie 
Published: October 2024

Terbatasnya kapasitas IPv4 yang hanya mendukung sekitar 4,3 miliar alamat unik mendesak pengembangan sistem pengalamatan yang lebih besar. IPv6 dikembangkan untuk mengatasi keterbatasan ini, menyediakan alamat yang lebih luas serta membawa perbaikan dalam manajemen alamat dan keamanan. Pada jaringan yang andal dan efisien, penting untuk menanggulangi kegagalan dan error yang dapat menurunkan Quality of Service (QoS). QoS memastikan jaringan yang memerlukan keandalan, bandwidth tinggi, atau latensi rendah dapat berfungsi optimal. Salah satu metode untuk mengatasi kegagalan jaringan adalah menggunakan First Hop Redundancy Protocol (FHRP), seperti HSRP (Hot Standby Router Protocol) dan GLBP (Gateway Load Balancing Protocol). Penelitian ini menunjukkan bahwa GLBP pada IPv6 memberikan performa jaringan terbaik dibandingkan protokol lainnya. GLBP pada IPv6 mencapai throughput tertinggi sebesar 93.95130523 Bytes dan delay terendah sebesar 1.000519298 detik dalam kondisi normal. Selain itu, pada kondisi gangguan, GLBP pada IPv6 memiliki downtime terendah sebesar 3.7 detik dan packet loss paling rendah sebesar 0,1%.
IMPLEMENTASI STRATEGI PAIKEM DALAM MENINGKATKAN MOTIVASI BELAJAR SISYA DI PASRAMAN SAMIAGA
Authors: Sintia Ni Kadek 
Published: October 2024

Artikel ini bertujuan untuk menganalisis implementasi strategi Pembelajaran, Aktif, Inovatif, Kreatif, Efektif, dan Menyenangkan (PAIKEM) dalam meningkatkan motivasi belajar sisya di Pasraman Samiaga. Pasraman merupakan lembaga pendidikan Hindu yang memiliki peran krusial dalam mewujudkan generasi muda yang bermoral dan berintelektual. Namun pembelajaran yang monoton, sistem pembelajaran kelas rangkap, kurangnya penggunaan teknologi, dan kesenjangan antara materi yang dibutuhkan dan diterima merupakan beberapa hal yang mempengaruhi motivasi belajar sisya. Sebagai salah satu upaya acarya di Pasraman Samiaga yaitu mengimplementasikan strategi PAIKEM. Penelitian ini menggunakan pendekatan kualitatif dengan metode pengumpulan data melalui observasi langsung non partisipan, wawancara langsung tidak terstruktur, dan studi dokumentasi. Analisis data dalam penelitian ini, dilakukan melalui reduksi data, penyajian data, dan penarikan kesimpulan. hasil Hasil analisis data menunjukan bahwa implementasi strategi Pembelajaran Aktif, Inovatif, Kreatif, Efektif, dan Menyenangkan (PAIKEM) di Pasraman Samiaga dapat meningkatkan motivasi belajar sisya. Hal ini terlihat dari peningkatan semangat belajar, sisya tidak merasa tertekan atau tegang, sisya terdorong untuk aktif dan tidak bosan, sisya termotivasi untuk lebih giat belajar, sisya bertanya kepada guru atau teman ketika ada materi yang belum dimen, menyadari pentingnya belajar, dan percaya bahwa usaha yang dilakukan tidak akan menghianati hasil.

Keywords: Strategi, PAIKEM, Motivasi Belajar, Pasraman
Does dance therapy benefit the improvement of blood pressure and blood lipid in patients with hypertension? A systematic review and meta-analysis
Authors: Wang Jialin , Yin Yikun , Yu Zhengze , Lin Qihan , Liu Yongsheng 
Published: October 2024

ObjectiveHypertension is a risk factor of cardiovascular disease. Dance, a type of aerobic exercise, is beneficial as a therapy in reducing blood pressure. This study aimed to systematically review the therapeutic effectiveness of dance therapy (DT) on blood pressure and blood lipid of patients with hypertension.MethodsSearching CNKI, VIP, Wan Fang Databases, CBM, PubMed, EBSCO (MEDLINE), Cochrane Library, and Web of Science to collect randomized controlled trials (RCTs) about dance therapy in the treatment of patients with hypertension according to the inclusion and exclusion criteria, with the search time ranged from the date of database construction to January 2024. The Cochrane risk-of-bias tool and PEDro were used to evaluate the risk of included trials. The meta-analysis was implemented by using RevMan 5.4 and Stata 12.0 software.ResultsA total of 983 patients were included in 11 randomized controlled trials. According to the meta-analysis, compared with the control group, Dance Therapy effectively reduced systolic blood pressure (SBP) [MD = −7.45, 95% CI (−8.50, −6.39), p &lt; 0.0001] and diastolic blood pressure (DBP) [MD = −2.95, 95% CI (−3.78, −2.13), p &lt; 0.0001], and it increased high-density lipoprotein cholesterol (HDL-C) [MD = 0.20, 95% CI (−0.02, 0.42), p &lt; 0.0001]. The subgroup analysis results showed that the treatment efficacy was more excellent with the frequency more than 3 times per week, the cycle less than 12 weeks, and the duration less than 60 min every time.ConclusionThe results indicates that SBP, DBP, and HDL-C in hypertensive patients have been effectively improved after dance therapy intervention. In addition, it is recommended to implement dance therapy for hypertensive patients with a treatment cycle of 12 weeks, and treat at least 3 times a week, with each treatment duration controlled within 60 min.Systematic Review Registration[http://www.crd.york.ac.uk/PROSPERO], identifier [CRD42024500807].
Targeting TGFβ with chimeric switch receptor and secreted trap to improve T cells anti-tumor activity
Authors: Matikhina Tatyana , Cohen Cyrille J. 
Published: October 2024

IntroductionTGFβ is a major immunoinhibitory factor present in the microenvironment of solid tumors. Various cancer types acquire the ability to overexpress TGFβ to escape immune response. Specifically, TGFβ dampens cytotoxic T cell activity, and its presence has been correlated with tumor invasion and poor prognosis.MethodsIn this study, we developed two approaches to counteract the effects of TGFβ and provide a functional advantage to genetically engineered T cells in the immunoinhibitory tumor milieu. We designed a TGFβRI-based co-stimulatory switch receptor (CSRI), comprising the TGFβ receptor I extracellular binding domain and a 4-1BB co-stimulatory signaling moiety. Additionally, we tested the efficacy of a TGFβ-binding scFv trap produced by T cells.ResultsWe demonstrated that both approaches enhanced tumor-specific T cell cytokine secretion, upregulated activation markers, and reduced inhibition markers upon co-culture with melanoma targets. Furthermore, CSRI and the anti-TGFβ trap exhibited improved anti-tumor function in vivo.ConclusionOverall, we show that targeting the TGFβ pathway can enhance cellular immunotherapy.
Identification of beneficial populations for targeted-immunotherapy combinations: tailoring later-line care for patients with pMMR/MSS metastatic colorectal cancer
Authors: Li Dan , Jin Hui , Liu Yan , Liu Jiayin , Zhang Xue , Wang Long , Fan Zhisong , Feng Li , Zuo Jing , Han Jing , Wang Yudong 
Published: October 2024

ObjectiveThis study explores the benefits of targeted-immunotherapy combination in third-line or beyond treatment for microsatellite stable (MSS) metastatic colorectal cancer (mCRC) in a real-world setting.MethodsPatients with MSS mCRC who were treated with either a targeted-immunotherapy combination or targeted therapy alone in the third-line or beyond setting at our hospital from August 2018 to August 2022 were included in the study. Inclusion criteria comprised patients treated with targeted therapy alone or in combination with immunotherapy. Effectiveness was compared between treatments, and patients with the potential to benefit from targeted-immunotherapy combination were identified.ResultsAmong 71 patients, 31 received targeted therapies alone (TT group) and 40 received a combination of targeted therapy and immunotherapy (TI group). The TI group had higher objective response rates (20% vs 3.2%) and disease control rates (82.5% vs 58.1%). The median progression-free survival was significantly better in the TI group (4.6 vs 4.1 months, P = 0.027). Liver metastasis was associated with poor prognosis, while patients with only lung metastases had the longest median progression-free survival of 12.3 months with combination therapy.ConclusionThe study indicates that targeted-immunotherapy combination offers more benefits than targeted therapy alone for MSS mCRC in the third-line or beyond setting.
Tumor-related IGF2BP1-derived molecular subtypes to predict prognosis and immune microenvironment in head and neck squamous cell carcinoma
Authors: Ding Qin , Liu Mingzhu , Pan Yuhui , Wu Ziyi , Wang Jing , Li Yi , Liu Xiaoyong , Lai Jinghua , Hu Dan , Qiu Sufang 
Published: October 2024

BackgroundRecent studies have underscored the biological significance of RNA modifications in tumorigenicity and progression. However, the potential roles of RNA modifications in immune regulation and the formation of the tumor microenvironment (TME) in head and neck squamous carcinoma (HNSC) remain unclear.MethodsWe collected 199 untreated HNSC samples and clinicopathological data from Fujian Provincial Cancer Hospital. MeRIP-seq and RNA-seq were performed to generate methylation and gene expression profiles, respectively. Consensus molecular subtyping was employed to identify prognosis-related genes and RNA modification patterns in HNSC. Experiments confirmed the potential oncogenic behavior influenced by key genes. Molecular subtypes were identified through consensus clustering and validated using external cohort validation sets.ResultsAmong the RNA modification-related genes, IGF2BP1 emerged as the most prognostic. HNSC patients were categorized into high and low IGF2BP1 expression groups. High-expressing patients exhibited poorer survival and reduced chemosensitivity, coupled with increased tumor mutational burden, low PD-L1 expression, and limited immune cell infiltration, indicative of aggressive disease. Analysis revealed two distinct RNA modification patterns associated with IGF2BP1 expression: biosynthetically intense type (BIT) and oncogenically active type (OAT), each characterized by distinct clinical features, outcomes, and biological pathways. In an independent immunotherapy cohort, BIT patients displayed enhanced immune responses and sustained clinical benefits.ConclusionsThis study highlights the crucial link between RNA modification and TME diversity. Evaluating RNA modification in tumors improves our understanding of TME features and supports the development of effective immunotherapy strategies.