bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differentiating tidal and groundwater dynamics from barrier island framework geology: Testing the utility of portable multifrequency electromagnetic induction profilers
Authors: Weymer Bradley A. , Everett Mark E. , Houser Chris , Wernette Phil , Barrineau Patrick 
Published: August 2016

Electromagnetic induction (EMI) techniques are becoming increasingly popular for near-surface coastal geophysical applications. However, few studies have explored the capabilities and limitations of portable multifrequency EMI profilers for mapping large-scale ([Formula: see text]) barrier island hydrogeology. The purpose of this study is to investigate the influence of groundwater dynamics on apparent conductivity [Formula: see text] to separate the effects of hydrology and geology from the [Formula: see text] signal. Shore-normal and alongshore surveys were performed within a highly conductive barrier island/wind-tidal flat system at Padre Island National Seashore, Texas, USA. Assessments of instrument calibration and signal drift suggest that [Formula: see text] measurements are stable, but vary with height and location across the beach. Repeatability tests confirm [Formula: see text] values using different boom orientations collected during the same day are reproducible. Measurements over a 12 h tidal cycle suggest that there is a tide-dependent step response in [Formula: see text], complicating data processing and interpretation. Shore-normal surveys across the barrier/wind-tidal flats show that [Formula: see text] is roughly negatively correlated with topography and these relationships can be used for characterizing different coastal habitats. For all surveys, [Formula: see text] increases with decreasing frequency. Alongshore surveys performed during different seasons and beach states reveal a high degree of variability in [Formula: see text]. Here, it is argued that surveys collected during dry conditions characterize the underlying framework geology, whereas these features are somewhat masked during wet conditions. Differences in EMI signals should be viewed in a relative sense rather than as absolute magnitudes. Small-scale heterogeneities are related to changing hydrology, whereas low-frequency signals at the broadest scales reveal variations in framework geology. Multiple surveys should be done at different times of the year and tidal states before geologic interpretations can confidently be made from EMI surveys in coastal environments. This strategy enables the geophysicist to separate the effects of hydrology and geology from the [Formula: see text] signal.
Correlation of Ki-67 indices from biopsy and resection specimens of neuroendocrine tumours
Authors: Barnes J , Johnson SJ , French JJ 
Published: August 2016

INTRODUCTIONNeuroendocrine tumours (NETs) are a heterogeneous group of tumours with a highly variable presentation and prognosis. Management decisions are complex. Ki-67 levels in tissue samples are a key indicator used to grade tumours and guide treatment. This study assessed whether the Ki-67 index and tumour grade generated from tissue samples correlated with that assessed in resection specimens.METHODSThis was a retrospective cohort analysis of all patients who had both a tissue sample and a resection specimen analysed in our trust, a tertiary referral centre, during 2012 and 2013.RESULTSData from 36 patients were reviewed. Ki-67 indices from tissue samples and resection specimens showed strong correlation (r=0.95, p<0.001). Tumour grading was the same in the tissue sample and resection specimens for 22 patients (61.1%). In four patients (11.1%), the tissue sample overestimated the grade while in ten (27.8%), the sample underestimated the grade.CONCLUSIONSIn most cases, the Ki-67 index and tumour grade from the tissue sample matched that of the resection specimen. However, in nearly 40% of cases, the tissue sample grading did not match the resection tumour grading. In the majority of these, the tissue sample underestimated disease activity. A low Ki-67 index in a tissue sample should therefore be taken as provisional and should not, in isolation, persuade clinicians to choose a more conservative treatment approach if there is clinical, biochemical or radiological evidence suggestive of a more aggressive disease pathology.
Koncepce liberalismu a demokracie v edukačním procesu: dekonstrukce neoliberální dominance v RVP
Authors: Květina Jan 
Published: August 2016

Abstrakt: Tato studie si klade za cíl posoudit, do jaké míry je současný vzdělávací program českého gymnaziálního školství determinován základními principy liberálně-demokratické ideologie, a v jakém rozsahu je schopen formovat v postojové rovině žáků pluralistické paradigma. Pro realizaci tohoto výzkumného cíle práce využívá diskurzivní analýzy klíčových kompetencí definovaných v RVP, jejímž prostřednictvím identifikuje hlavní hodnotové inkoherence tohoto materiálu a zároveň dokazuje, že ve vzdělávacím systému dominuje jednostranná interpretace liberálních a demokratických hodnot založená na principech neoliberálních dogmat. Klíčová slova: vzdělání, pluralismus, neoliberalismus, demokracie, RVP, diskurzivní analýza.
Current Progress of Capacitive Deionization for Removal of Pollutant Ions
Authors: Gaikwad Mahendra S. , Balomajumder Chandrajit 
Published: August 2016

AbstractA mini review of a recently developing water purification technology capacitive deionization (CDI) applied for removal of pollutant ions is provided. The current progress of CDI for removal of different pollutant ions such as arsenic, fluoride, boron, phosphate, lithium, copper, cadmium, ferric, and nitrate ions is presented. This paper aims at motivating new research opportunities in capacitive deionization technology for removal of pollutant ions from polluted water.
Chances, risks and limitations of neoadjuvant therapy in surgical oncology
Authors: Lordick Florian , Gockel Ines 
Published: August 2016

AbstractOver the last decades, neoadjuvant treatment has been established as a standard of care for a variety of tumor types in visceral oncology. Neoadjuvant treatment is recommended in locally advanced esophageal and gastric cancer as well as in rectal cancer. In borderline resectable pancreatic cancer, neoadjuvant therapy is an emerging treatment concept, whereas in resectable colorectal liver metastases, neoadjuvant treatment is often used, although the evidence for improvement of survival outcomes is rather weak. What makes neoadjuvant treatment attractive from a surgical oncology viewpoint is its ability to shrink tumors to a smaller size and to increase the chances for complete resection with clear surgical margins, which is a prerequisite for cure. Studies suggest that local tumor control is increased in some visceral tumor types, especially with neoadjuvant chemoradiotherapy. In some other studies, a better control of systemic disease has contributed to significantly improved survival rates. Additionally, delaying surgery offers the chance to bring the patient into a better general condition for major surgery, but it also confers the risk of progression. Although it is a relatively rare event, cancers may progress locally during neoadjuvant treatment or distant metastases may occur, jeopardizing a curative surgical treatment approach. Although this is seen as risk of neoadjuvant treatment, it can also be seen as a chance to select only those patients for surgery who have a better control of systemic disease. Some studies showed increased perioperative morbidity in patients who underwent neoadjuvant treatment, which is another potential disadvantage. Optimal multidisciplinary teamwork is key to controlling that risk. Meanwhile, the neoadjuvant treatment period is also used as a “window of opportunity” for studying the activity of novel drugs and for investigating predictive and prognostic biomarkers of chemoradiotherapy and radiochemotherapy. Although the benefits of neoadjuvant treatment have been clearly established, the risk of overtreatment of cancers with an unfavorable prognosis remains an issue. All indications for neoadjuvant treatment are based on clinical staging. Even if staging is done meticulously, making use of all recommended diagnostic modalities, the risk of overstaging and understaging remains considerable and may lead to false indications for neoadjuvant treatment. Finally, despite all developments and emerging concepts in medical oncology, many cancers remain resistant to the currently available drugs and radiation. This may in part be due to specific molecular resistance mechanisms that are marginally understood thus far. Neoadjuvant treatment has been one of the major advances in multidisciplinary oncology in the last decades, requiring a dedicated treatment team and an optimal infrastructure for complex oncology care. This article discusses the goals and novel directions as well as limitations in neoadjuvant treatment of visceral cancers.
The role of partial androgen deficiency in aging men in the development of benign prostatic hyperplasia and prostate cancer
Authors: Pechersky Alexander V. 
Published: August 2016

AbstractOnce people reach 35-40 years, they have a decrease in their pool of pluripotent stem cells, and show a violation of tissue renewal, a decrease in the number of cell-producers of testosterone (Leidig cells) and a reduction in testosterone circulating in the blood. Partial androgen deficiency in aging men violates division and differentiation of androgen-dependent cells and increases the risk for development of benign prostatic hyperplasia and prostate cancer. The recovery of testosterone production and regeneration helps make a decrease in proliferative activity, and the rehabilitation of regulation of androgen-dependent cells of the prostate and other tissues and organs, as well as reduce insulin resistance among older men.
Maternity and Absence in Shakespearean Romance
Authors: Hopkins Helen 
Published: August 2016

Abstract
The equivocation of the private life of Elizabethan and Jacobean subjects with the public life of monarchy and state endowed mothers with an import, and therefore a power, not previously acknowledged. These changes provoked a fear of female disruption to patriarchal structures which found its way onto Shakespeare’s stage by the representation of mothers as ‘unnatural’ agents of chaos, associated with witchcraft, murder, dangerous ambition, and infidelity; if not by complete absence, which “posits the sacrifice of the mother’s desire as the basis of the ideal society” (Rose, 1991: 313). I suggest that in the late romances, specifically The Winter's Tale and The Tempest, Shakespeare found a form that could demonstrate the complexity of the mother’s position, while still resolving the action with a satisfactory ending that presented a stable continuation of patriarchal lineage. The fathers rely on a fantasy of parthenogenesis to relocate the role of the mother in themselves, ensuring the children are free from her corruptive influence and the bloodlines are safe. However, as all themes return to maternity - chastity, fertility, lineage for example - the fantasy of eradicating the mother is shown to be limited even in the artificial realm of the romance.
The New Romanian Shakespeare Series on the Move: From Page to Stage and Screen
Authors: Volceanov George 
Published: August 2016

Abstract
This article aims at presenting the impact that the New Romanian Shakespeare edition launched in 2010 by George Volceanov has had on the literati and theatres so far. It is, therefore, a stocktaking exercise and its main goal is to provide Shakespeare scholars with an initial data base for further investigation of theatrical productions which use the new translation as significant moments in the history of Shakespeare’s reception in Romania and, on the other hand, to occasion some reflective remarks on the six years of the series now at its tenth volume and 26 plays plus the Sonnets.
Metagenomic Analysis of Slovak Bryndza Cheese Using Next-Generation 16S rDNA Amplicon Sequencing
Authors: Planý Matej , Kuchta Tomáš , Šoltýs Katarína , Szemes Tomáš , Pangallo Domenico , Siekel Peter 
Published: August 2016

Abstract Knowledge about diversity and taxonomic structure of the microbial population present in traditional fermented foods plays a key role in starter culture selection, safety improvement and quality enhancement of the end product. Aim of this study was to investigate microbial consortia composition in Slovak bryndza cheese. For this purpose, we used culture-independent approach based on 16S rDNA amplicon sequencing using next generation sequencing platform. Results obtained by the analysis of three commercial (produced on industrial scale in winter season) and one traditional (artisanal, most valued, produced in May) Slovak bryndza cheese sample were compared. A diverse prokaryotic microflora composed mostly of the genera Lactococcus, Streptococcus, Lactobacillus, and Enterococcus was identified. Lactococcus lactis subsp. lactis and Lactococcus lactis subsp. cremoris were the dominant taxons in all tested samples. Second most abundant species, detected in all bryndza cheeses, were Lactococcus fujiensis and Lactococcus taiwanensis, independently by two different approaches, using different reference 16S rRNA genes databases (Greengenes and NCBI respectively). They have been detected in bryndza cheese samples in substantial amount for the first time. The narrowest microbial diversity was observed in a sample made with a starter culture from pasteurised milk. Metagenomic analysis by high-throughput sequencing using 16S rRNA genes seems to be a powerful tool for studying the structure of the microbial population in cheeses.
Degradation of Synthetic Dyes by Laccases – A Mini-Review
Authors: Legerská Barbora , Chmelová Daniela , Ondrejovič Miroslav 
Published: August 2016

AbstractLaccases provide a promising future as a tool to be used in the field of biodegradation of synthetic dyes with different chemical structures. These enzymes are able to oxidize a wide range of phenolic substrates without the presence of additional co-factors. Laccases have been confirmed for their potential of synthetic dye degradation from wastewater and degradation products of these enzymatic reactions become less toxic than selected dyes. This study discusses the potential of laccase enzymes as agents for laccase-catalyzed degradation in terms of biodegradation efficiency of synthetic dyes, specifically: azo dyes, triphenylmethane, indigo and anthraquinone dyes. Review also summarizes the laccase-catalyzed degradation mechanisms of the selected synthetic dyes, as well as the degradation products and the toxicity of the dyes and their degradation products.
The awareness of testicular cancer among young males in the Lubelskie Region / Świadomość nowotworu jądra wśród młodych mężczyzn na Lubelszczyźnie
Authors: Piróg Marta , Padała Olga , Podgórniak Marta , Putowski Maciej , Sadowska Monika , Artur Wdowiak 
Published: August 2016

Abstract
Aim. The aim of the study was to analyze the awareness of testicular cancer and prevention behaviors among male residents of the Lubelskie Province.
Material and methods. The study was conducted in 2015 and involved 131 men aged 17 to 38. A questionnaire designed by the authors was used as a research tool. The obtained results were analyzed statistically and the Chi2 test was used.
Results. Using a 0-5 scale, every fourth participant assessed their knowledge as 0, while only 7% assessed it as 5. The average level was 3.1 among students of medicine, while among students of other faculties it was 1.6. The Internet was cited as the most popular source of information about testicular cancer, while the healthcare staff was ranked as the last one. As much as 83.2% of men from the study group had never learnt how to perform testicular self-examination properly. Medical students were more likely to carry out this procedure regularly - 32%, compared to non-medical students - 12%.
Conclusions. The awareness of testicular cancer among the population of young men from the Lubelskie Province is insufficient, which is the main cause of their failure to perform regular self-examinations. The role of general practitioners is too little, despite the fact that most males consider them as the most reliable source of the information. Implementation of education and training programs for prevention of testicular cancer is required.
Zastosowanie elektroterapii TENS w łagodzeniu bólu porodowego / Application of TENS electrotherapy in alleviating labour pain
Authors: Sowa Magdalena , Ciechanowska Katarzyna , Głowacka Iwona 
Published: August 2016

Abstract
Introduction. Easing labour pain is an extremely important issue in obstetric practice. Various physiotherapy methods are increasingly often applied in obstetric practice. Transcutaneous electric nerve stimulation (TENS) aiming at central and peripheral modulation of pain sensation is one of them.
Aim. The aim of the study was to analyse the impact of transcutaneous electrical stimulation (TENS) on easing labour pain.
Summary. The TENS method is regarded as effective since it increases both the pain threshold and secretion of endogenous opioids. Non-pharmacological methods of pain management during labour, including electrotherapy TENS methods are safe and can be used in most patients.
Peripheral cross-linguistic interference in the acquisition of accusative clitics by Romanian–Hungarian simultaneous bilinguals
Authors: Tomescu Veronica , Avram Larisa 
Published: August 2016

AbstractThis paper presents the results of the first study of the acquisition of Accusative clitics in Romanian by Romanian–Hungarian bilingual children. Our data show that the acquisition route is similar to the one in a monolingual setting. An interesting observation which arises from this study is that two structures which are superficially similar in the two languages favour the occurrence of non-target constructions, unavailable in either of the two languages. They occur under bilingual conditions via non-language-specific mechanisms, such as comparison and analogy. This is why their use, age of onset, and end of influence are subject to individual variation. Their analysis reveals that even structures which are the result of non-language-specific mechanisms, when drawing on morpho-syntactic knowledge, can fall within the range of constructions made available by Universal Grammar. The same superficial similarity seems to boost the acquisition of clitics by Romanian–Hungarian bilinguals.
Role of Interferon-Gamma (Ifn-γ) in Immune Response Regulation in Hiv-1 and Hiv-1 + Mycobacterium Tuberculosis (Tb) Infected Patients / Interferona-gamma (Ifn-γ) Loma Imūnās Atbildes Regulēšanā Pacientiem Ar HIV-1 un HIV-1 + mycobacterium Tuberculosis
Authors: Januškevica Inga , Rozentāle Baiba , Hagina Elvīra , Eglīte Jeīena , Kolupajeva Tatjana , Storozenko Jeīena , Guseva Ludmila , Lejnieks Aivars 
Published: August 2016

Abstract
The aim of this research was to investigate the role of IFN-γ in interaction between IL-10, IL-18, IL-1b, CD4 cell counts and HIV-1 RNA viral load in the development of HIV-1 in patients co-infected with Mycobacterium tuberculosis (TB). The study was conducted by Rīga East Clinical University Hospital with data from the HIV-1 register, in collaboration with the RSU Joint Laboratory of Clinical Immunology and Immunogenetics. 200 HIV-1 infected patients and 184 HIV-1 with TB co-infection patients divided in four groups were included in the study. IFN-γ, IL-10, IL-18, IL-1b levels were measured in serum with commercially enzyme-linked immunosorbent assay (ELISA Vector-Best Corporation, Novosibirsk, Russia). CD4 cell counts were measured by flow Partec IVD cytometry (USA). HIV-1 RNA quantification was performed using the COBAS AmpliPrep/COBAS Taqman HIV-1 Test (Germany). All groups were compared with each another. IFN-γ production was significantly lower, and IL-10 and CD4 cell counts were significantly higher, in HIV-1 patients without TB compared with the other groups. The group with HIV-1 and TB had significantly elevated IL-18 production. HIV patients with primary TB had significantly elevated IFN-γ production and HIV-1 RNA viral load and significantly lower IL-10 production.
Decreasing Prevalence of Multidrug-Resistant Acinetobacter Baumannii in Rīga East University Hospital / Multirezistentās Acinetobacter Baumannii Izplatības Mazināšanās Rīgas Austrumu Klīniskajā Universitātes Slimnīcā
Authors: Liepiņš Māris , Sīmanis Raimonds , Lejnieks Aivars 
Published: August 2016

Abstract
There has been an increasing tendency of infections caused by multidrug-resistant organisms (MDRO), including multidrug-resistant Acinetobacter baumannii (MDRAB), in the Rīga East University Hospital (REUH) during the last decade. Over the last two years (2014-2015), this tendency has reversed and the prevalence of MDRAB has decreased considerably. In this study we assessed the prevalence of MDRAB in intensive care units (ICUs), internal medicine, surgery units and analysed antibiotic sensitivity profiles. In addition, we determined if current infection control measures are preventing further increase of infections caused by MDRAB in REUH.
Retrospective Acinetobacter baumannii prevalence data were collected for the period from 2009 until 2012. For the time period from the beginning of 2013 until 2015, after implementing such infection control measures as control of compliance to hand hygiene guidelines, a review of central venous catheter insertion protocols and regular search for sources of MDRAB in hospital environment, prospective follow-up of new cases was conducted. Antimicrobial sensitivity profiles were assessed for the period from 2013 until 2015. Data were processed with the statistical software WHONET 5.5. Bacteria identification and antibiotic susceptibility testing were performed by VITEK 2 compact, BioMerieux, France. The prevalence of MDRAB in the period 2009 to 2013 increased from 71 to 217 cases per year, but from between 2013 (time of implementing infection control measures) and 2015 it decreased to 113 cases in 2015. In the three year period (2013-2015), the proportion of MDRAB causing bloodstream infections (BSI) and central nervous system infections (CNSI) was 15.85% from all identified MDRAB cases. Of the 113 MDRAB infections diagnosed in 2015, BSI was found in 16.81% cases (n = 19). Antibiotic resistance testing showed that colistin is the most effective drug against MDRAB. The majority of Acinetobacter baumannii isolates were resistant to Ampicillin/Sulbactam, Piperacillin/Tazobactam, Ceftazidime, Cefepime, Imipenem, Meropenem, Amikacin, Gentamicin, Tobramycin, and Ciprofloxacin. Over the last two years (2014-2015), prevalence of MDRAB infections decreased considerably. In the time period from 2013 to 2014, resistance of Acinetobacter baumannii increased to imipenem, ciprofloxacin and colistin, while decreased slightly to amikacin. Rigorous infection control measures, such as identification and elimination of new MDRAB sources in environment, review of the central venous catheter insertion protocol and improvements in hand hygiene, are crucial for decreasing distribution of and invasive infections caused by MDRAB in the hospital environment.
The impact of gastroesophageal reflux in the ENT pathology
Authors: Melinte Violeta , Sarafoleanu Codrut 
Published: August 2016

Abstract
Frequently encountered in medical practice, the gastroesophageal reflux (GER) is a chronic condition characterized by the passage of gastric acid or gastric contents into the esophagus. In otorhinolaryngology, the diagnosis of pharyngo-laryngeal or rhinosinusal inflammatory conditions secondary to GER is one of exclusion and it is based on a detailed anamnesis in which we are interested in symptoms, behavioural and medical risk factors, on the ENT clinical examination, the laryngo-fibroscopical assessment, the phoniatric examination, the barite pharyngo-esogastric exam, the upper gastrointestinal endoscopy and the esophageal manometry.
The authors are making a systematization of the contribution of the gastroesophageal reflux has in the ENT pathology, emphasising the sympytoms and the most frequent associated pathological entities.