bluuebunny/crossref_metadata_2025_split huggingface dataset:
The myths of economic development and the ‘must do's’ to avoid them
Authors: Collits Paul 
Published: December 2015

AbstractLocal economic development has recently emerged in Western nations, including across Australasia, as both a concern of local and regional governments and as a profession. The connections between theory and practice have been complex, and defining best practice is difficult. It seems clear, however, that generally practice is far from perfect, and often reflects poor thinking and a lack of understanding of the underlying drivers of economic development. Academic fads have often driven practice, and there are many myths associated with local economic development practice. The paper unpacks some of the most persistent and important myths, and suggests ways for practitioners, regional leaders and stakeholders alike to overcome the traps associated with the myths.
Correlation between Fusarium head blight severity and DON content in triticale as revealed by phenotypic and molecular data
Authors: Miedaner Thomas , Kalih Rasha , Großmann Maren S. , Maurer Hans P. 
Published: December 2015

AbstractFusarium head blight (FHB) in triticale (× Triticosecale Wittmack) results in yield losses and mycotoxin contamination, for example, by deoxynivalenol (DON). This study aimed to analyse the correlation between FHB severity and DON content in a DH population of 146 entries across environments. Additionally, Fusarium damaged kernel (FDK) rating, heading stage and plant height were recorded. Highly significant (P < 0.001) genotypic variances were found throughout, but also significant (P < 0.001) genotype–environment interaction variances occurred. Correlation between FHB severity and heading stage or plant height was low (r = 0.144 and r = −0.153, P < 0.10). A prediction of DON content from FHB severity or FDK rating is not possible caused by low correlations (r = 0.315 and 0.572, respectively, P < 0.001). A common quantitative trait locus (QTL) for all FHB‐related traits was found on wheat chromosome 2A being of minor importance for FHB severity, but of high importance for DON content and FDK rating. Another QTL on rye chromosome 5R was more important for FHB severity. In conclusion, DON content has to be measured in triticale after selection for FHB severity to gain for healthy and mycotoxin‐reduced feed.
Ultrasound and computed tomography of the iliosacral lymphatic centre in dogs with anal sac gland carcinoma
Authors: Pollard R. E. , Fuller M. C. , Steffey M. A. 
Published: December 2015

AbstractIn this prospective study, we hypothesized that computed tomography (CT) would identify more normal and abnormal iliosacral lymph nodes (LNs) than abdominal ultrasound in dogs with anal sac gland carcinoma (ASGC). Twelve client‐owned dogs with ASGC but without distant metastasis were enrolled. Abdominal ultrasound and contrast‐enhanced CT scans of the abdomen were obtained. Iliosacral LNs were counted and assessed for location, laterality and size. Significantly (P < 0.00001) more iliosacral LNs were identified with CT (61) than ultrasound (30), including significantly (P = 0.00012) more medial iliac LNs with CT (33) than ultrasound (19). There was no difference in number of internal iliac LNs identified with CT versus ultrasound. Significantly (P = 0.000061) more sacral LNs were identified with CT (15) than ultrasound (0). Ultrasound identified slightly more (7) abnormal iliosacral LNs than CT (5). Contrast CT was able to identify more normal but not more abnormal LNs than ultrasound.
THE DEVELOPMENT OF WEB-BASED MANAGEMENT INFORMATION SYSTEM FOR THE CHILD MALNUTRITION SURVEILLANCE
Authors: Delimayanti Mera K. , Mulyono Sigit , Waluyanti Fajar T. 
Published: December 2015

The monitoring process of children’s health (nutrition fulfillment) carried out by Puskesmas (Community Health Center/ CHC) officials as front personnel of health services for local communities is not well implemented yet. In addition, the unavailability of the early warning system for the identification of child malnutrition had worsen the problem. It is primarily caused by less accurate patient recording system within CHCs, as well as ineffective and inefficient data reporting since the process is carried out manually. This research proposes an alternative early detecting system of child malnutrition within a number of regions in which CHCs are located based on the development of web-based system for the child malnutrition surveillance and integrated into an Internet network to facilitate its usage by medical personnel. The system is mainly aimed to ease CHC officials to input such systematic patient data that it is relatively fast to identify if there is a possible indication of child malnutrition within a particular area. The system is expected to be an early warning detector of children malnutrition cases and assist the head of health authority as a decision maker to take initiatives accordingly. Recommendations from the system are made available for users following which, health authority and the public can monitor the operation of the system directly by accessing the output data from the nutritional status study of a certain area.
ROLE OF ENTREPRENEURIAL LEADERSHIP AND COMMERCIALIZATION OF UNIVERSITY RESEARCH: A REVIEW
Authors: Pane Sri Gustina , Kumar M Dileep 
Published: December 2015

Recently, universities are playing active role in economic development of the country, besides their traditional role of teaching and research. Research has shown that the increasing global trend of entrepreneurial activities emerging in major academic institutions have left universities with no choice but to re-invent their operational activities and engage themselves in entrepreneurial activities to remain competitive globally. However this transformation required entrepreneurial leadership that can lead universities to enhance the commercialization of their research. Thus, in this regard, entrepreneurial leadership is inevitable for universities. Current study provided the review of literature which argues the need for entrepreneurial leadership in the context of commercialization of university research.
GLOBAL POSITIONING SYSTEM AND GLOBAL SYSTEM FOR MOBILE COMMUNICATION MODEM APPLICATION AS CAR POSITION AND FUEL MONITORING SYSTEM
Authors: Anisah Masayu , Taqwa Ahmad , Amperawan Amperawan , Evelina Evelina , Rasyad Sabilal 
Published: December 2015

The distribution of fuel oil carried by the tanker to the Fuel Stations is hard to be monitored. There are cases where the driver, who steals the fuel from the tank, harder to be tracked down. To overcome this problem, researchers used Global Positioning System and Global System for Mobile Modem Communication as an application. The research integrates multiple electronic Global Positioning System device, ultrasonic sensor, Arduino and mobile modem in the system. The device is placed in the carriage fuel tank of the tanker. This system aims to determine the car's position and content of the fuel tank. It will retrieve current car position and carriage content and send it over Short Message and voice call over Mobile modem. A program, built with Delphi will retrieve the message and point out the car position and tank level accurately on Google Maps. The results obtained indicated that the error is approximately ± 0.05 and deviation is 0 latitude and 0.00362 longitude. For further development, we plan to improve two parameters by increasing warnings with the increase in the capacity of the sensors. From the overall discussion in this study, it can be concluded that the equipment content monitoring system can be well applied.
BIOSORPTION OF HEAVY METALS BY SCENEDESMUS SP. ISOLATED FROM THE TEMPORARY WATERS OF ENDAU ROMPIN, JOHOR, MALAYSIA
Authors: Muhammad Nmaya Muhammad , Gogoba Ishaq Aisha , Agam Mohammed Arif , Matias-Peralta Hazel Monica , Khaled Nadiah , Alhaji Yabagi Jibrin , Kimpa Muhammad Isa 
Published: December 2015

Contamination of soil and water by heavy metals threatens the well-being of humans and the natural environment. The need for a cost-effective and efficient method for their removal has led researchers to develop interest in microorganisms that show resistance to these toxic metals. In this work, we used inductive coupled plasma mass spectroscopy to detect the presence of heavy metals Aluminum (Al), lead (Pb), Nickel (Ni) and Copper (Cu) in the wild pond Sungai Buaya, in Johor Malaysia. This research shows the biosorption ability of living cells of micro algae Scenedesmus sp. as a function of metal concentration for these metals. It was found that 78% of Al, 74% of Pb, 24% of Cu and 16% of Ni was taken up by the microalgae. This shows that Scenedesmus sp. has potential for use in further research works particularly in bioremediation of contaminated water and also biosynthesis of nanoparticles.
PRELIMINARY STUDY ON IN VITRO PROPAGATION OF Macaranga tanarius (Mahang)
Authors: Abdullah Nazirah , Hassan Nor Hasnida , Yahya Muhammad Fuad , Koter Rosdi , A. Rahman Siti Suhaila , Ismail Haliza , Khalid Rozidah , Abdullah Samsul Bahrin , Abdullah Rohani 
Published: December 2015

Macaranga tanarius locally known as Mahang, belongs to Euphorbiaceae family is a native plant in Malaysia. This invasive species is mostly found in disturbed forest. Macaranga genus is a medium size tree and can grow up to 24 m tall. Macaranga genus is a fast growing species, evergreen trees with soft and light wood. M. tanarius wood can be used to produce high quality particle board and pulp besides other usage as good firewood. Phytochemical studies on M. tanarius have discovered the presence of tannin that can be used as toughing agent on fishing net as well as dyeing agent. The leaves extract of this species have shown potential as an antioxidant when tested with 2, 2 – diphenyl-picrylhydrazyl (DPPH) anti-oxidant assay. Due to its benefits in multiple industries, production of sustainable and high quality planting material cannot be avoided. Tissue culture is one of the best approaches to meet this demand. In this preliminary study, surface sterilization protocol for M. tanarius using seed as explants has been developed. 3 different surface sterilization methods have been tested. Based on the percentage of contamination and response, the best method for surface sterilization of M. tanarius is by using 30% of Chlorox® which produced more than 90% clean culture and the best response among other methods; swelling (38%), formation of roots (8%), shoots (2%) as well as minimum amount of damage tissues. Explants from germinated plantlets in vitro were further tested on four different basal medium to find the most suitable basal medium for M. tanarius growth which were full strength Woody Plant Media (WPM), half strength Woody Plant Media (½ WPM), Murashige and Skoog media (MS) and half strength Murashige and Skoog media (½ MS). Explants cultured on WPM basal medium produced healthy rooted plantlet in terms of size and colour of shoot and leaves. ½ WPM media can also induce rooting in M. tanarius whereas in MS and ½ MS media the explants turn to brown and died. For shoot multiplication experiment, WPM medium supplemented with different types of cytokinin; BAP and TDZ at different concentration have been tested. WPM medium supplemented with 0.1 mg/l TDZ showed the highest percentage of shoot induction with 100% shoot induced and average produces three new shoots per explants.
ORNITHINE DECARBOXYLASE GENE EXPRESSION IN HUMAN LUNG ADENOCARCINOMA CELL (A549) TREATED WITH POMEGRANATE JUICE
Authors: Abdul Ghani Radiah , Nik Abdul Malek Nik Nurasyikin , Md. Yusof Najwa Farhah , Jamil Elyna Fatini 
Published: December 2015

The polyamine biosynthesis pathway plays a significant role in cell growth, both normal and malignant. As polyamines are crucial in cellular growth and differentiation, they are linked to the development of cancer, with higher polyamine level observed in cancerous cells than in healthy cells. Accordingly, suppressing the polyamine pathway has been found to disrupt tumour development. Chemoprevention is considered a more feasible option in cancer management than chemotherapy, with a focus on natural chemopreventive agent. Pomegranate is known to inhibit several progression of lung cancer, although prior studies on the chemopreventive effect of pomegranate on lung cancer did not explore into polyamine pathway. Hence, this study investigated the effect of pomegranate juice on the polyamine pathway, by focusing on the biosynthesis involving ornithine decarboxylase (ODC), the rate limiting enzyme in the pathway. Quantitative polymerase chain reaction (qPCR) was applied to quantify the changes in ODC gene expression in A549 cells treated with pomegranate. The inhibition of growth was determined using Trypan Blue exclusion and the changes in intracellular polyamine in pomegranate treated cells was observed using High Performance Liquid Chromatography (HPLC). It was found that there was inhibition of A549 cell growth and reduced in intracellular polyamine content in pomegranate treated cells. The ODC expression was significantly inhibited compared to untreated cells, with a 48-fold difference. While this finding supports the hypothesis, there is much yet to be elucidated regarding its exact mechanism.
Analysis of complications of reverse total shoulder arthroplasty
Authors: Russo Raffaele , Rotonda Giuseppe , Ciccarelli Michele , Cautiero Fabio 
Published: December 2015

Purpose: the aim of this study was to analyze complications of reverse total shoulder arthroplasty (RTSA) used to treat different shoulder diseases.
Methods: from March 2000 to March 2013, 195 RTSA were implanted by the senior Author. The indications for reverse prosthesis surgery were secondary osteoarthritis (OA) in 49 cases, irreparable rotator cuff tear (RCT) in 48 cases, and complex humeral fractures in 75 cases, while 19 were patients requiring surgical revision for first prosthesis implant. We used different prostheses with different designs.
Results: the clinical and radiological results of all the patients were analyzed retrospectively at an average follow-up of 7 years. The cases were divided into four groups on the basis of the diagnosis and complications were classified as perioperative, postoperative, or late. The mean total Constant score improved from 28 to 69 points in the OA group; from 21 to 70.8 points in the irreparable RCT group, to 76.4 in the fracture group, and from 16.6 to 59.8 points in the revision group. Scapular notching was observed in 59 cases (30.2%). Thirty-three other complications (16.9%) were observed, namely: hematomas (n=3), instability of the humeral component (n=1), scapular spine fractures (n=2), ulnar nerve deficit (n=2), long thoracic nerve palsy (n=2), deep infections (n=2), periprosthetic fractures (n=6), glenoid fractures (n=2), implant loosening (n=2), anterior deltoid muscle deficiency (n=2) and periarticular heterotopic calcifications (n=9).
Conclusions: the rates of complications, especially fractures, reported in the present study were lower than those reported in the current literature.
Level of evidence: Level IV, therapeutic case series.
Herramientas didácticas para el desarrollo técnico musical del guitarrista clásico a través de ejes problémicos
Authors: Quevedo Barrero Cesar Augusto , Samper Arbeláez Andrés , Posada Ramos Carlos 
Published: December 2015

<p>Este artículo presenta los resultados de un estudio desarrollado por el área de guitarra clásica del Departamento de Música de la Pontificia Universidad Javeriana (PUJ) en Bogotá, Colombia. El estudio indagó sobre las dificultades técnico-musicales más recurrentes entre estudiantes de guitarra de los programas infantil y juvenil, pregrado y posgrado de la PUJ. Con base en las dificultades detectadas se realizó una recopilación de material musical para apoyar el desarrollo de habilidades en la formación del guitarrista clásico. El material pedagógico resultante hace énfasis en el desarrollo musical, plantea una estructura no lineal de aprendizaje, incorpora el uso de materiales latino americanos e incluye ejercicios de improvisación, lectura a primera vista y grafías no convencionales. La metodología empleada fue de carácter cualitativo y se fundamentó en un ejercicio triple de reflexión didáctica, sistematización de materiales existentes y creación de piezas originales.</p>
UNA PROPUESTA EXPERIMENTAL EN LA ENSEÑANZA DE LA MÚSICA EN SECUNDARIA
Authors: BOTELLA NICOLÁS ANA MARÍA , ADELL VALERO JOSÉ RAFAEL 
Published: December 2015

<p>En el presente artículo se pretende describir una experiencia enfocada hacia la enseñanza de la Música en Secundaria, aplicando el Método Cooperativo por Proyectos. Se trata de determinar su eficacia y pertinencia en el marco del aprendizaje por competencias mediante un proceso de investigación-acción que se llevó a cabo con alumnos de 2º y 3º de ESO. Para comprobar su efectividad se ha contrastado dicho método con otro de referencia: la Clase Magistral. Las conclusiones se justifican mediante un análisis estadístico, realizado de manera cualitativa y cuantitativa.</p><p>La propuesta se realiza con el fin de comprobar si ésta experiencia da respuesta a las necesidades sociales que exige el mundo actual y también si favorece que el alumnado piense y actúe de manera reflexiva colaborando con los demás y actuando desde una perspectiva creativa y crítica, siguiendo los conceptos teóricos de Schafer, Delalande, Reibel y Paynter.</p>
Dynamical Downscaling of ERA-Interim Temperature and Precipitation for Alaska
Authors: Bieniek Peter A. , Bhatt Uma S. , Walsh John E. , Rupp T. Scott , Zhang Jing , Krieger Jeremy R. , Lader Rick 
Published: December 2015

AbstractThe European Centre for Medium-Range Weather Forecasts interim reanalysis (ERA-Interim) has been downscaled using a regional model covering Alaska at 20-km spatial and hourly temporal resolution for 1979–2013. Stakeholders can utilize these enhanced-resolution data to investigate climate- and weather-related phenomena in Alaska. Temperature and precipitation are analyzed and compared among ERA-Interim, WRF Model downscaling, and in situ observations. Relative to ERA-Interim, the downscaling is shown to improve the spatial representation of temperature and precipitation around Alaska’s complex terrain. Improvements include increased winter and decreased summer higher-elevation downscaled seasonal average temperatures. Precipitation is also enhanced over higher elevations in all seasons relative to the reanalysis. These spatial distributions of temperature and precipitation are consistent with the few available gridded observational datasets that account for topography. The downscaled precipitation generally exceeds observationally derived estimates in all seasons over mainland Alaska, and it is less than observations in the southeast. Temperature biases tended to be more mixed, and the downscaling reduces absolute bias at higher elevations, especially in winter. Careful selection of data for local site analysis from the downscaling can help to reduce these biases, especially those due to inconsistencies in elevation. Improved meteorological station coverage at higher elevations will be necessary to better evaluate gridded downscaled products in Alaska because biases vary and may even change sign with elevation.
Assimilation of Infrared Radiance Observations with Sensitivity to Land Surfaces in the Canadian Ensemble–Variational System
Authors: Dutta S. K. , Garand L. , Heilliette S. 
Published: December 2015

AbstractThis study highlights recent progress at the Canadian Meteorological Centre in the assimilation of Atmospheric Infrared Sounder (AIRS) and Infrared Atmospheric Sounding Interferometer (IASI) radiance observations that are sensitive to land surfaces. The assimilation is carried out using the Canadian global ensemble–variational system. That system benefits from flow-dependent background-error statistics that include covariances between surface skin temperature and atmospheric variables. Up to 142 channels from both AIRS and IASI are assimilated. A detailed database of spectral surface emissivity is used. Forecasts are evaluated against ERA-Interim analyses, own-cycle analyses, and radiosonde observations. A conservative approach is taken, with restrictive conditions on topography and surface emissivity. From 2-month assimilation experiments, a significant positive impact is obtained in the Northern Hemisphere extratropics beyond day 2 from the surface to the upper troposphere. The impact is mixed in other regions, depending on level or forecast lead time. Causes for these mixed results are examined in view of future experiments and eventual operational implementation.
Comparison of Simulated Polarimetric Signatures in Idealized Supercell Storms Using Two-Moment Bulk Microphysics Schemes in WRF
Authors: Johnson Marcus , Jung Youngsun , Dawson Daniel T. , Xue Ming 
Published: December 2015

Abstract
Microphysics parameterization becomes increasingly important as the model grid spacing increases toward convection-resolving scales. The performance of several partially or fully two-moment (2M) schemes within the Weather Research and Forecasting (WRF) Model, version 3.5.1, chosen because of their well-documented advantages over one-moment (1M) schemes, is evaluated with respect to their ability in producing the well-known polarimetric radar signatures found within supercell storms. Such signatures include the ZDR and KDP columns, the ZDR arc, the midlevel ZDR and ρHV rings, the hail signature in the forward-flank downdraft, and the KDP foot. Polarimetric variables are computed from WRF Model output using a polarimetric radar simulator. It is found that microphysics schemes with a 1M rimed-ice category are unable to simulate the ZDR arc, despite containing a 2M rain category. It is also found that a hail-like rimed-ice category (in addition to graupel) may be necessary to reproduce the observed hail signature. For the microphysics schemes that only contain a graupel-like rimed-ice category, only very wet graupel particles are able to reach the lowest model level, which did not adequately reduce ZDR in this signature. The most realistic signatures overall are found with microphysics schemes that are fully 2M with a separate hail category.
KRAS mutant lung cancer: progress thus far on an elusive therapeutic target
Authors: Bhattacharya Saveri , Socinski Mark A. , Burns Timothy F. 
Published: December 2015

AbstractThe KRAS mutation remains the most common driver mutation in patients with non‐small cell lung cancer (NSCLC) and confers a poor prognosis. Thus far, efforts to target this mutation over the last two decades have been unsuccessful. Over the past 5 years, many efforts to develop drugs that target the RAS‐RAF‐MEK‐ERK (MAPK) pathway have resulted in enhanced understanding of the KRAS mutant NSCLC and have provided optimism that this disease can be targeted.