bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Idol talks!” AI-driven image to text to speech: illustrated by an application to images of deities
Authors: Sherly P. Steffy , Velvizhy P. 
Published: October 2024

Abstract
This work aims to provide an innovative solution to enhance the accessibility of images by an innovative image to text to speech system. It is applied to Hindu and Christian divine images. The method is applicable, among others, to enhance cultural understanding of these images by the visually impaired. The proposed system utilizes advanced object detection techniques like YOLO V5 and caption generation techniques like ensemble models. The system accurately identifies significant objects in images of Deities. These objects are then translated into descriptive and culturally relevant text through a Google text-to-speech synthesis module. The incorporation of text generation techniques from images introduces a new perspective to the proposed work. The aim is to provide a more comprehensive understanding of the visual content and allow visually impaired individuals to connect with the spiritual elements of deities through the immersive experience of auditory perception through a multimodal approach to make them feel inclusive in the community. This work is also applicable to preserve Cultural Heritage, Tourism and integrating with Virtual Reality (VR) and Augmented Reality (AR). Images of the artistic cultural legacy are hardly available in annotated databases, particularly those featuring idols. So we gathered, transcribed, and created a new database of Religious Idols in order to satisfy this requirement. In this paper, we experimented how to handle an issue of religious idol recognition using deep neural networks. In order to achieve this outcome, the network is first pre-trained on various deep learning models, and the best one which outperforms others is chosen. The proposed model achieves an accuracy of 96.75% for idol detection, and an approximate 97.06% accuracy for text generation according to the BLEU score.
Hyperdimensional computing: a framework for stochastic computation and symbolic AI
Authors: Heddes Mike , Nunes Igor , Givargis Tony , Nicolau Alexandru , Veidenbaum Alex 
Published: October 2024

AbstractHyperdimensional Computing (HDC), also known as Vector Symbolic Architectures (VSA), is a neuro-inspired computing framework that exploits high-dimensional random vector spaces. HDC uses extremely parallelizable arithmetic to provide computational solutions that balance accuracy, efficiency and robustness. The majority of current HDC research focuses on the learning capabilities of these high-dimensional spaces. However, a tangential research direction investigates the properties of these high-dimensional spaces more generally as a probabilistic model for computation. In this manuscript, we provide an approachable, yet thorough, survey of the components of HDC. To highlight the dual use of HDC, we provide an in-depth analysis of two vastly different applications. The first uses HDC in a learning setting to classify graphs. Graphs are among the most important forms of information representation, and graph learning in IoT and sensor networks introduces challenges because of the limited compute capabilities. Compared to the state-of-the-art Graph Neural Networks, our proposed method achieves comparable accuracy, while training and inference times are on average 14.6× and 2.0× faster, respectively. Secondly, we analyse a dynamic hash table that uses a novel hypervector type called circular-hypervectors to map requests to a dynamic set of resources. The proposed hyperdimensional hashing method has the efficiency to be deployed in large systems. Moreover, our approach remains unaffected by a realistic level of memory errors which causes significant mismatches for existing methods.
360° CZT-SPECT/CT cameras: 99mTc- and 177Lu-phantom-based evaluation under clinical conditions
Authors: Hoog Christopher , Koulibaly Pierre-Malick , Sas Nicolas , Imbert Laetitia , Le Rouzic Gilles , Popoff Romain , Badel Jean-Noël , Ferrer Ludovic 
Published: October 2024

Abstract
Purpose
For the first time, three currently available 360° CZT-SPECT/CT cameras were compared under clinical conditions using phantom-based measurements.

Methods
A 99mTc- and a 177Lu-customized NEMA IEC body phantom were imaged with three different cameras, StarGuide (GE Healthcare), VERITON-CT versions 200 (V200) and 400 (V400) (Spectrum Dynamics Medical) under the same clinical conditions. Energy resolution and volumetric sensitivity were evaluated from energy spectra. Vendors provided the best reconstruction parameters dedicated to visualization and/or quantification, based on their respective software developments. For both 99mTc- and 177Lu-phantoms, noise level, quantification accuracy, and recovery coefficient (RC) were performed with 3DSlicer. Image quality metrics from an approach called “task-based” were computed with iQMetrix-CT on 99mTc visual reconstructions to assess, through spatial frequencies, noise texture in the background (NPS) and contrast restitution of a hot insert (TTF). Spatial resolution indices were calculated from frequencies corresponding to TTF10% and TTF50%.

Results
Despite the higher sensitivity of VERITON cameras and the enhanced energy resolution of the V400 (3.2% at 140 keV, 5.2% at 113 keV, and 3.6% at 208 keV), StarGuide presents comparable image quality. This highlights the need to differentiate sensitivity from count quality, which is influenced by hardware design (collimator, detector block) and conditions image quality as well as the reconstruction process (algorithms, scatter correction, noise regulation). For 99mTc imaging, the quantitative image optimization approach based on RCmean for StarGuide versus RCmax for V200 and V400 systems (RCmean/RCmax: 0.9/1.8; 0.5/0.9; 0.5/0.9 respectively—Ø37 mm). SRTB10/50 showed nearly equivalent spatial resolution performances across the different reconstructed images. For 177Lu imaging, the 113 keV imaging of the V200 and V400 systems demonstrated strong performances in both image quality and quantification, while StarGuide and V400 systems offer even better potential due to their ability to exploit signals from both the 113 and 208 keV peaks. 177Lu quantification was optimized according to RCmax for all cameras and reconstructions (1.07 ± 0.09—Ø37 mm).

Conclusions
The three cameras have equivalent potential for 99mTc imaging, while StarGuide and V400 have demonstrated higher potential for 177Lu. Dedicated visual or quantitative reconstructions offer better specific performances compared to the unified visual/quantitative reconstruction. The task-based approach appears to be promising for in-depth comparison of images in the context of system characterization/comparison and protocol optimization.
Pleiotropic regulatory function of the RNA chaperone Hfq in the Pseudomonas protegens FD6
Authors: Wen Deyu , Hu Jieyu , Gao Ziying , Xing Chenglin , Xiao Yao , Wu Tao , Wu Xiaogang , Zhang Qingxia 
Published: October 2024

AbstractThe rhizosphere bacterium Pseudomonas protegens FD6, which is associated with the production of antibiotics such as pyoluteorin (PLT) and 2,4-diacetylphloroglucinol (2,4-DAPG), has strong antagonistic effects on phytopathogens. Hfq is a conserved RNA chaperone involved in the regulation of stress tolerance, antibiotic production, and bacterial virulence. Here, we determined the regulatory effects of Hfq on biocontrol traits in P. protegens FD6. Mutation of hfq in FD6 reduced the growth rate, swimming and swarming ability, and production of proteases, siderophores, and hydrogen cyanide (HCN). Transmission electron microscopy revealed that disruption of hfq led to the loss of flagella. Furthermore, Hfq exerted a suppressive effect on biofilm formation and PLT production while not affecting antagonistic activity and control effect against tomato bacterial wilt. However, Hfq positively regulated the production of 2,4-DAPG and activated the phlD expression. Additionally, mutation of hfq abolished the function of the type VI secretion system (T6SS) due to a decrease in the expression of T6SS-related genes. Overall, these results suggest that Hfq plays a pleiotropic role in modulating the expression of biocontrol trait-related genes in P. protegens FD6.
Multiomic Characterization and Molecular Profiling of Nuclear Protein in Testis Carcinoma
Authors: Kroening Gianna , Luo Jia , Evans Mark G. , Adeyelu Tolulope , Ou Sai-hong Ignatius , Arter Zhaohui L. , Wise-Draper Trisha M. , Sukari Ammar , Azmi Asfar S. , Braxton David R. , Elliott Andrew , Bryant David A. , Oberley Matthew J. , Kim Chul , Shapiro Geoffrey I. , French Christopher A. , Nagasaka Misako 
Published: October 2024

PURPOSE

Nuclear protein in testis carcinoma (NC) is an underdiagnosed and aggressive squamous/poorly differentiated cancer characterized by rearrangement of the gene
NUTM1
on chromosome 15q14. Co-occurring alternations have not been fully characterized.

METHODS
We analyzed the genomic and immune landscape of 54 cases of NC that underwent DNA- and RNA-based NGS sequencing (Caris).

RESULTS

While NC is driven by
NUTM1
fusion oncoproteins, co-occurring DNA mutations in epigenetic or cell cycle pathways were observed in 26% of cases. There was no significant difference between the fusion partner of
NUTM1
and co-occurring gene mutations. RNA sequencing analysis showed increased
MYC
pathway activity in NC compared with head and neck squamous cell carcinoma (HNSCC) and lung squamous cell carcinoma (LUSC), which is consistent with the known pathophysiology of NC. Characterization of the NC tumor microenvironment using RNA sequencing revealed significantly lower immune cell infiltration compared with HNSCC and LUSC. NC was 10× higher in patients with HNSCC and LUSC younger than 50 years than in those older than 70 years.

CONCLUSION

To our knowledge, this is the first series of NC profiled broadly at the DNA and RNA level. We observed fewer intratumoral immune cells by RNA sequencing, which may be associated with anecdotal data of lack of immunotherapy benefit in NC. High
MYC
pathway activity in NC supports ongoing trials targeting
MYC
suppression. The incidence of NC among patients younger than 50 years with LUSC/HNSCC supports testing for NC in these patients. The prognosis of NCs remains dismal, and future studies should focus on improving the response to immunotherapy and targeting MYC.
Mechanisms of drug resistance in nutrient-depleted colorectal cancer cells: insights into lysosomal and mitochondrial drug sequestration
Authors: Köse Serra Gülse , Güleç Taşkıran Aliye Ezgi 
Published: October 2024

ABSTRACT
This Review delves into the mechanisms behind drug resistance in colorectal cancer (CRC), particularly examining the role of nutrient depletion and its contribution to multidrug resistance (MDR). The study highlights metabolic adaptations of cancer cells as well as metabolic adaptations of cancer cells under low nutrient availability, including shifts in glycolysis and lipid metabolism. It emphasizes the significance of MDR1 and its encoded efflux transporter, P-glycoprotein (P-gp/B1), in mediating drug resistance and how pathways such as HIF1α, AKT, and mTOR influence the expression of P-gp/B1 under limited nutrient availability. Additionally, the Review explores the dual roles of autophagy in drug sensitivity and resistance under nutrient limited conditions. It further investigates the involvement of lysosomes and mitochondria, focusing on their roles in drug sequestration and the challenges posed by lysosomal entrapment facilitated by non-enzymatic processes and ABC transporters like P-gp/B1. Finally, the Review underscores the importance of understanding the interplay between drug sequestration, lysosomal functions, nutrient depletion, and MDR1 gene modulation. It suggests innovative strategies, including structural modifications and nanotechnology, as promising approaches to overcoming drug resistance in cancer therapy.
Appropriate sagittal positioning of femoral components in total knee arthroplasty to prevent fracture and loosening
Authors: Wan Qian , Han Qing , Liu Yang , Chen Hao , Zhang Aobo , Zhao Xue , Wang Jincheng 
Published: October 2024

AimsThis study aimed to investigate the optimal sagittal positioning of the uncemented femoral component in total knee arthroplasty to minimize the risk of aseptic loosening and periprosthetic fracture.MethodsTen different sagittal placements of the femoral component, ranging from -5 mm (causing anterior notch) to +4 mm (causing anterior gap), were analyzed using finite element analysis. Both gait and squat loading conditions were simulated, and Von Mises stress and interface micromotion were evaluated to assess fracture and loosening risk.ResultsDuring gait, varied sagittal positioning did not lead to excessive Von Mises stress or micromotion. However, under squat conditions, posterior positioning (-4 and -5 mm) resulted in stress exceeding 150 MPa at the femoral notch, indicating potential fracture risk. Conversely, +1 mm and 0 mm sagittal positions demonstrated minimal interface micromotion.ConclusionSlightly anterior sagittal positioning (+1 mm) or neutral positioning (0 mm) effectively reduced stress concentration at the femoral notch and minimized interface micromotion. Thus, these positions are deemed suitable to decrease the risk of aseptic loosening and periprosthetic femoral fracture.
Spindle vibration induced optical performance deterioration and its trans-scale characterization for diamond turned large-aperture optics
Authors: Guo Pan , Xiong Zhiwen , Dong Zengwen , Zhang Shaojian 
Published: October 2024

In ultra-precision diamond turning of large-aperture optics, the spindle vibration (SV) would cause a deterioration of optical performance. To discuss this issue, the spindle vibration was first excited by a series of designed mass center errors for diamond turning of large-aperture optics. Then, a trans-scale characterization was developed to reveal its dynamic behaviors by combining a white light interferometer and laser interferometer. Next, the amplitude variations were quantitatively evaluated by surface texture parameters and the scale bandwidth was revealed through power spectrum density (PSD). Finally, the point spread function (PSF), encircled energy ratio (EER), and modulation transfer function (MTF) were analyzed and compared. The results indicated that, with the increased SV, Sq and Sz increased and Ssk and Sku showed a transition from skew to normal height distribution. PSD showed that spindle vibration mainly affected the large-scale components rather than the small-scale components. The shape of PSF changed from a standard ring to a dispersed half ring. At the 1 µm radius of the Airy disk, the EER decreased from 82.0% (no SV) to 27.5% (high SV). At the scale of 200mm−1, the MTF decreased from 0.84 (no SV) to 0.44 (high SV). The work provides a fundamental understanding of the evolutionary mechanism of spindle vibration induced optical performance deterioration.
Integrasi Metode Gravity dan Metode Geomagnetik Menggunakan Dekonvolusi Euler untuk Delineasi Struktur pada Sistem Panas Bumi di Kawasan Candi Umbul-Telomoyo, Magelang, Jawa Tengah
Authors: Hanatha Fauzi Daffa , Hamid Hanafiah 
Published: October 2024

Penelitian berlokasi di daerah outflow Candi Umbul -Telomoyo yang memiliki sistem panas bumi yang ditandai dengan adanya manifestasi air panas. Pemetaan struktur bawah permukaan dilakukan dengan metode geomagnet dan gravity dengan menggunakan analisis euler deconvolution untuk memperjelas orientasi, kedalaman, dan lokasi struktur. Hasil yang diperoleh berdasarkan nilai gravity, zona manifestasi berada pada nilai anomali gravity rendah dengan nilai 3,3 mgal hingga 7,4 mgal dan terdapat zona anomali tinggi di sebelah selatan manifestasi dengan nilai 7,4 mgal hingga 13,4 mgal. Berdasarkan nilai geomagnet, terdapat nilai magnetik rendah pada daerah manifestasi dengan nilai -472,8 nT hingga -89,7 nT dan terdapat nilai tinggi pada bagian selatan dengan nilai -89,7 nT hingga 415,4 nT. Zona anomali rendah pada daerah manifestasi mata air panas diinterpretasikan sebagai zona hancuran akibat struktur dan telah teralterasi. Hasil euler deconvolution menunjukkan adanya sesar utama berarah barat-timur yang diinterpretasikan sebagai sesar pengontrol panas bumi di daerah penelitian. Perhitungan euler deconvolution pada anomali geomagnet didapatkan struktur sedalam ±156,8 m dan pada anomali gravity didapatkan struktur sedalam ±524,9 m.
Concept and development of a telemedical supervision system for anesthesiology in operating rooms using the interoperable communication standard ISO/IEEE 11073 SDC
Authors: Roth Jonas , Voigt Verena , Yilmaz Okan , Schauwinhold Michael , Czaplik Michael , Follmann Andreas , Pereira Carina B. 
Published: October 2024

Abstract

Objectives
Discussion of a telemedical supervision system for anesthesiology in the operating room using the interoperable communication protocol SDC. Validation of a first conceptual demonstrator and highlight of strengths and weaknesses.

Methods
The system includes relevant medical devices, a central anesthesia workstation (AN-WS), and a remote supervision workstation (SV-WS) and the concept uses the interoperability standard ISO/IEEE 11073 SDC. The validation method involves a human patient simulator, and the system is tested in an intervention study with 16 resident anesthetists supervised by a senior anesthetist.

Results
This study presents a novel tele-supervision system that enables remote patient monitoring and communication between anesthesia providers and supervisors. It is composed of connected medical devices via SDC, a central AN-WS and a mobile remote SV-WS. The system is designed to handle multiple ORs and route the data to a single SV-WS. It enables audio/video connections and text chatting between the workstations and offers the supervisor to switch between cameras in the OR. Through a validation study the feasibility and usefulness of the system was assessed.

Conclusions
Validation results highlighted, that such system might not replace physically present supervisors but is able to provide supervision for scenarios where supervision is currently not available or only under adverse circumstances.
Linguistic Justice and Ethnic Minority Education in Vietnam
Authors: Nguyen Tien-Duc , Tran-Thi Thu-Thuy 
Published: October 2024

Abstract
The relationship between language and education is deeply intertwined, with each domain exerting a profound influence upon the other. Drawing on international law on minority rights, the right to education and protection of endangered languages, this article seeks to probe the extent to which linguistic justice in the education of ethnic minorities in Vietnam is realized, an important issue in the preservation and promotion of ethnic cultural identity and linguistic diversity. It argues that despite the alignment of Vietnamese laws with international standards, as suggested by a legal positivist approach, ethnic minorities in Vietnam still encounter significant challenges when attempting to use their native languages in educational contexts. This article examines the hurdles faced by ethnic minorities in Vietnam in achieving linguistic justice for ethnic minorities in Vietnam from the perspective of international law. By exploring this intersection, it contributes to a deeper understanding of the complex issues surrounding language rights and minority rights within the context of Vietnamese education policy.
Crystal structure of dicarbonyl (μ2-indole-2-carboxylato κ2
O:O′)tris(triphenylarsine-κAs)dirhodium(I) acetone solvate, C68H56As3NO5Rh2
Authors: Elmakki Mohammed A. , Alexander Orbett T. , Venter Johan A. , Roodt Andreas 
Published: October 2024

Abstract
C68H56As3NO5Rh2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 14.048(4) Å, b = 14.569(4) Å, c = 17.942(5) Å, α = 92.273(9)°, β = 112.728(9)°, γ = 115.910(9)°, V = 2948.7(13) Å3, Z = 2, R
gt(F) = 0.0378, wR
ref(F
2) = 0.0990, T = 100 K.
Improving effect and mechanism on service performance of asphalt binder modified by PW polymer
Authors: Zhang Honggang , Xuan Weian , Chen Jie , Sun Xiaolong , Zhu Yunchu 
Published: October 2024

Abstract
To achieve the improving effect of polymer material on the sustainability of asphalt pavement materials, the PW modifier was selected as anti-aging modifier of asphalt. The microscopic morphology and structural characteristics of polymer modifier were characterized by using focused ion beam electron microscopy and energy-dispersive spectrometer. The functional group composition of the PW modifier was analyzed by Fourier transform infrared spectroscopy. The PW-modified asphalt was prepared for ultraviolet (UV) aging resistance evaluation. The microscopic morphology and surface roughness evolution of polymer-modified asphalt were investigated during the whole period of UV aging. Under the condition of UV aging, the functional group composition of polymer-modified asphalt was studied. The results showed that the microscopic morphology of the PW polymer modifier was mainly crystal structure, mainly composed of C and O elements. The PW polymer modifier could improve the aging resistance of asphalt binder effectively and alleviate the generation of asphalt microcracks in the process of UV aging. The addition of PW polymer modifier could inhibit the formation and accumulation of typical functional group inside asphalt binder during the UV aging period, which could achieve the effective control of asphalt UV aging behavior.
РАСШИРЕННЫЙ СРАВНИТЕЛЬНЫЙ СПЕКТРАЛЬНЫЙ АНАЛИЗ РАЗЛИЧНЫХ БИОМАТЕРИАЛОВ С ПРИМЕНЕНИЕМ МАТЕМАТИЧЕСКИХ МЕТОДОВ ОБРАБОТКИ
Authors: Е.В. ТИМЧЕНКО , П.Е. ТИМЧЕНКО , О.О. ФРОЛОВ , Л.Т. ВОЛОВА , И.В. БАЖУТОВА , М.Ю. ВЛАСОВ 
Published: October 2024

Проведены эксперименты по применению математических методов обработки для расширенного сравнительного анализа состава биоматериалов и брефоматриксов. В качестве основных математических методов обработки спектров комбинационного рассеяния (КР) исследуемых биоматериалов использованы линейный дискриминантный анализ (LDA), ROC-анализ. Установлено, что деминерализованные биоматериалы из ювенильного дентина обладают меньшей антигенностью по сравнению с брефоматриксами.
Experiments are conducted on the use of mathematical processing methods for an expanded comparative analysis of the composition of biomaterials and brefomatrices. The linear discriminant analysis and ROC analysis are used as the main mathematical methods for processing the Raman spectra of the biomaterials under study. It is found that demineralized biomaterials from juvenile dentin are less antigenic compared to brefomatrices.