bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gold to aurostibite transformation and formation of Au-Ag-Sb
phases: the Krásná Hora deposit, Czech Republic
Authors: Zachariáš Jiří , Němec Matěj 
Published: August 2017

AbstractRare phases of the Au–Ag–Sb system were recognized in the Krásná Hora Sb-Au
deposit (Sb 1.5–3 wt.%; Au 3–5 ppm), Czech Republic which correspond to
auriferous dyscrasite (up to 7 at.% Au), auriferous allargentum (up to 34
at.% Au), and an unnamed phase with composition similar to the eutectics
(E1, E2) of the experimental Au–Ag–Sb system. The dominant ore mineral is
stibnite with rare native antimony, native gold and a Ag-Au alloy. Textural
relationships are well established: stibnite (early) →gold → aurostibite →
native antimony (late). Gold is present in four generations: Au-1 (0–15 at.%
Ag) is the most abundant type; Au-2 (20–70 at.% Ag) forms thin rims along
intra-grain boundaries of Au-1; Au-3 and Au-4 are rare and almost pure (∼0
at.% Ag). The formationof most of the Au-2 and of Au-Ag-Sb phases is
associated with Ag-mobilization coupled with the Au-1 to aurostibite
transformation via dissolution-precipitation and solid-state diffusion
processes at temperatures <200°C.
New arsenate minerals from the Arsenatnaya fumarole, Tolbachik
volcano, Kamchatka, Russia. VII. Pharmazincite, KZnAsO4
Authors: Pekov Igor V. , Yapaskurt Vasiliy O. , Belakovskiy Dmitry I. , Vigasina Marina F. , Zubkova Natalia V. , Sidorov Evgeny G. 
Published: August 2017

AbstractThe new mineral pharmazincite, KZnAsO4, was found in sublimates
of the Arsenatnaya fumarole at the Second scoria cone of the Northern
Breakthrough of the Great Tolbachik Fissure Eruption, Tolbachik volcano,
Kamchatka, Russia. It is closely associated with shchurovskyite,
dmisokolovite, bradaczekite, arsmirandite, tilasite, johillerite, tenorite,
hematite, aphthitalite and As-bearing orthoclase. Pharmazincite occurs as
prismatic to acicular crystals up to 1 mm long and up to 0.03 mm thick
typically combined in near parallel, radial or chaotic intergrowths,
open-work aggregates or crusts up to 2 mm across. Pharmazincite is
colourless to white, transparent, with a vitreous lustre. It is brittle,
with a stepped fracture and a perfect cleavage parallel to [001].
Dcalc is 4.75 g cm–3. Pharmazincite is optically
uniaxial (–),ω = 1.649(2), ε = 1.642(2). The Raman spectrum is reported. The
chemical composition (wt.%, electron-microprobe data) is: K2O
18.98, CaO 0.14, MgO 1.20, CuO 4.41, ZnO 27.58, Fe2O3
0.15, P2O5 0.50, As2O546.67,
total 99.63. The empirical formula, calculated based on 4 O apfu, is:
(K0.97Ca0.01)∑0.98(Zn0.82Cu0.13Mg0.07Fe0.013+)∑1.03(As0.98P0.02)∑1.00O4.The
strongest reflections of the powder X-ray diffraction pattern
[d,Å(I)(hkl)] are:
6.36 (28)(111), 4.64(45)(220), 4.35(48)(002), 3.260(36)(411),
3.179(100)(222), 2.770(26)(113), 2.676(77)(600), 2.278(15)(602) and
1.710(15)(713, 115). Pharmazincite is hexagonal, a =
18.501(4), c = 8.7114(9) Å, V = 2582.4(8)
Å3 and Z = 24 (single-crystal XRD data). Its
space group is P63, by analogy with synthetic
KZnAsO4 that has a crystal structure based upon a tetrahedral
tridymite-type{ZnAsO4}– framework. It is isostructural with
megakalsilite KAlSiO4. The new mineral is named for its chemical
constituents.
An application of the Rietveld refinement method to the mineralogy of a bauxite-bearing regolith in the Lower Amazon
Authors: Negrão Leonardo Boiadeiro Ayres , Costa Marcondes Lima da , Pöllmann Herbert , Horn Axel 
Published: August 2017

AbstractA comparison of Rietveld refinement results for a bauxite-bearing regolith and its clayey cover in the Amazon region was made with stoichiometric calculations from chemical analysis and partly from thermogravimetric results. For this investigation a profile in the bauxite-bearing regolith occurrence in the ALCOA bauxite mine at Juruti, Brazil was studied. The different minerals, their compositions and their low crystallinity in the different horizons were investigated and the contents determined. It is evident that some minerals show several generations and some chemical composition changes that must be included in the Rietveld refinement. Al-rich hematites and goethites are common along the bauxite profile. Amorphous contents were determined with rutile added as an internal standard and shown to have gibbsite- or kaolinite-like composition. The minerals could be quantified in the different horizons and the difficulties were mainly related to variable crystalline aspects of the phases. Rietveld refinement can be a powerful tool in bauxite prospecting, quality control and during mining and beneficiation of ore minerals using the adapted refinement strategies.
The promises and challenges of using gene mutations for patient stratification in follicular lymphoma
Authors: Weigert Oliver , Weinstock David M. 
Published: August 2017

Abstract
Follicular lymphoma (FL) is a clinically and molecularly highly heterogeneous disease. Most patients achieve long-lasting remissions and have excellent overall survival (OS) with current treatment. However, ∼20% of patients have early progression of disease and short OS. At present, therapies are not guided by individual risk or disease biology. Reliable tools for patient stratification are urgently needed to avoid overtreatment of low-risk patients and to prioritize alternative approaches in high-risk patients. A rapidly expanding repertoire of promising therapeutic options is available for clinical evaluation; however, the numbers of patients with FL and the resources to conduct adequately powered trials are limited. Recent studies have shown that gene mutations can serve as prognostic and/or predictive biomarkers, in particular when integrated into composite risk models. Before translating these findings into routine clinical practice, however, several challenges loom. We review aspects of “clinicogenetic” risk model development and validation that apply to FL and more generally to other cancers. Finally, we propose a crowdsourcing effort that could expedite the development, validation, refinement, and selection of risk models. A new era of collaboration and harmonization is required if we hope to transition from empiric selection of therapeutics to risk-based, biology-guided treatment of patients with FL.
Dealing with the death of a long term patient; what is the impact and how do podiatrists cope?
Authors: Robson Kristy , Williams Cylie M 
Published: August 2017

AbstractBackgroundIt is common for podiatrists and patients to develop long term professional relationships. Patient's decline in health or death may impact a practitioner's mental wellbeing. This research aimed to understand the impact of long term patient death on podiatrists and identify coping strategies.MethodAustralian podiatrists were eligible to participate if they had been practicing longer than 5 years and experienced the death of a long term patient in the previous 12 months. Individual semi‐structured interviews were conducted with podiatrists and were audio‐recorded, transcribed verbatim and individually analysed to identify key themes. Interpretative phenomenological analysis was used to explore the perceptions of podiatrists on the personal and professional impact following the death of a long term patient.ResultsFifteen podiatrists (11 female) with a median of 15 (range 8–50) years' experience participated.Three major themes emerged: acknowledging connections, willing to share and listen, and creating support through starting the conversation. Participants indicated importance in recognition of the emotional influence of professional‐patient relationships. They also discussed the importance of debriefing about death with the right person, which was most commonly colleagues. Participants talked about the emotional impact of death, suggesting the need for supporting discussion and resources, especially for new graduates.ConclusionDeath and dying can be an emotive topic and one which podiatrists may not be prepared for, yet likely to have to deal with throughout their career. These findings enable a better understanding of the impact of patient death and provide possible future directions for the profession to better support podiatrists in this area.
Profiling of cardio‐metabolic risk factors and medication utilisation among Type II diabetes patients in Ghana: a prospective cohort study
Authors: Adua Eric , Roberts Peter , Sakyi Samuel Asamoah , Yeboah Francis Agyemang , Dompreh Albert , Frimpong Kwasi , Anto Enoch Odame , Wang Wei 
Published: August 2017

AbstractBackgroundType II diabetes mellitus (T2DM) is complicated by multiple cardio‐metabolic risk factors. Controlling these factors requires lifestyle modifications alongside utilisation of anti‐diabetic medications. Different glucose lowering [(biguanides (BIGs), sulfonylureas (SUAs), thiazolidinediones (TNZ)], lipid lowering (statins), and anti‐hypertensive medicines [angiotensin converting enzyme inhibitors (ACEIs), calcium channel blockers (CCBs), angiotensin II receptor blockers (ARBs) and central acting drugs (CADs)] have been approved for controlling hyperglycaemia, dyslipidaemia and hypertension respectively. Here, we examined factors that characterise T2DM and explored the response to medication therapy among T2DM patients.MethodsThis prospective cohort study recruited 241 T2DM patients reporting at a clinic in Ghana, from January through to August, 2016. Each patient's demographic, medications and anthropometric data was obtained while information on medication adherence was captured using Morisky adherence scale‐8 (MMAS‐8). Fasting blood samples were collected for biochemical analysis.ResultsThe mean age of participants was 57.82 years for baseline and six‐month follow‐up. Physical activity differed at baseline and follow up (p < 0.05) but not body mass index (BMI). BIG alone, or in combination with SUA and TNZ did not improve glycaemic status at follow up (p > 0.05). Many participants using either ACEI or ARB were able to control their blood pressures. Among dyslipidaemia patients under statin treatment, there was an improved lipid profile at follow‐up.ConclusionsStatin medications are effective for reducing dyslipidaemia in T2DM patients. However, control of modifiable risk factors, particularly blood glucose and to a lesser degree blood pressure is suboptimal. Addressing these will require concomitant interventions including education on medication adherence and correct dietary plans, lifestyle modifications and physical activity.
An agent-based simulation of cooperation in the use of irrigation systems
Authors: Cai Jingjing , Xiong Hang 
Published: August 2017

AbstractThis study presents an agent-based simulation of the formation of cooperation in using irrigation. The simulation model is developed based on our understanding of the underlying mechanisms by which farmer households participate the cooperation. That is, a household first become a potential participant when the cost of cooperation it needs to sustain is not higher than the amount it can afford or is willing to pay; and on top of this, the propensity that the household participates is heavily affected by its personal characteristics and neighborhood effects. We use model to examine the impacts of initial participants and government support on both the reach and velocity of the cooperation diffusion. The model is calibrated to villages with successfully running Water User Association in central China. Our results show that government support plays a critical role but the initial participants do not matter much for different types of initial participants and network structure of the village.
Association of Pelvic and Para-Aortic Lymphadenectomy With Survival in Stage I Endometrioid Endometrial Cancer: Matched Cohort Analyses From the National Cancer Database
Authors: Seagle Brandon-Luke L. , Kocherginsky Masha , Shahabi Shohreh 
Published: August 2017

Purpose To estimate whether pelvic and para-aortic lymphadenectomy was associated with increased survival in stage I endometrioid endometrial cancer. Methods We performed matched cohort analyses of women with stage I endometrioid endometrial cancer who underwent hysterectomy with no lymphadenectomy, pelvic lymphadenectomy, or combined pelvic and para-aortic lymphadenectomy. Cox proportional hazards survival analyses were performed with inverse probability weights. Hazard ratios (HRs) were covariate and propensity score adjusted. Covariates included cancer center type, age, race, Hispanic ethnicity, insurance type, community median income quartile, comorbidity score, history of prior cancer, depth of myometrial invasion, tumor grade, tumor size, lymphovascular space invasion, cytology status, surgical margin status, hospital volume, and use of adjuvant radiotherapy or chemotherapy. Additional analyses included subset analyses by grade, sensitivity analyses with imputation of missing data, and testing for sensitivity to possible unmeasured confounding. Results Median (interquartile range [IQR]) lymph node counts were 0, 10 (5-15), and 20 (15-27) nodes in the no lymphadenectomy, pelvic, and combined pelvic and para-aortic lymphadenectomy–matched cohorts, respectively. Matched cohorts were well balanced. Two analyses were performed: no lymphadenectomy (n = 7,487) versus pelvic lymphadenectomy (n = 7,487), and pelvic lymphadenectomy (n = 7,060) versus combined pelvic and para-aortic lymphadenectomy (n = 7,060). Performance of pelvic lymphadenectomy was associated with increased survival compared with no lymphadenectomy (5-year survival [95% CI], 91.4% [90.2% to 92.6%] v 87.3% [85.9% to 88.8%]; HR, 0.71 [95% CI, 0.64 to 0.78]; P < .001). Addition of para-aortic lymphadenectomy was associated with increased survival compared with pelvic lymphadenectomy alone (5-year survival [95% CI], 91.0% [89.8% to 92.2%] v 89.8% [88.4% to 91.1%]; HR, 0.85 [95% CI, 0.77 to 0.95]; P = .003). Associations were robust to sensitivity analyses. Conclusion Lymphadenectomy was associated with increased survival in stage I endometrioid endometrial cancer. An adequately powered randomized trial is needed.
Distrust in the End-of-Life Care Provided to a Parent and Long-Term Negative Outcomes Among Bereaved Adolescents: A Population-Based Survey Study
Authors: Beernaert Kim , Kreicbergs Ulrika , Fürst Carl Johan , Nyberg Tommy , Steineck Gunnar , Bylund-Grenklo Tove 
Published: August 2017

Purpose Previous research shows that the death of a parent places children at risk for a number of negative outcomes. The role of trust in health care at the end of life has been acknowledged as crucial for patients and adult family members. However, the consequences of children’s distrust in the care provided to their parents remain unknown. Therefore, we investigated the negative long-term outcomes of cancer-bereaved sons’ and daughters’ distrust in the care that was provided to a dying parent. Methods We used a population-based nationwide survey to investigate self-reported distrust in the care provided and possible negative outcomes in 622 (73%) participants who had lost a parent as a result of cancer 6 to 9 years earlier, at ages 13 to 16 years. All participants were 18 years or older at the time of the survey. Results In those who reported no or little trust (ie, distrust) in the health care provided to their dying parents, we found statistically significantly higher risks of various negative outcomes at the time of survey: bitterness toward health care professionals for not having done everything that was possible (crude risk ratio [RR], 3.5; 95% CI, 2.3 to 5.1) and for having stopped treatment (RR, 3.4; 95% CI, 2.1 to 6.0), self-destructiveness (eg, self-injury [RR, 1.7; 95% CI, 1.2 to 2.4]), and psychological problems (eg, moderate to severe depression according to the Patient Health Questionnaire–9 [RR, 2.3; 95% CI, 1.5 to 3.5]). Conclusion In cancer-bereaved former adolescents, distrust in the health care provided to the dying parent is associated with a higher risk of negative long-term outcomes. The health care professionals involved in this care might play an important role in safeguarding the trust of adolescents.
Development of Stepwise-Field-Swept Solid-State NMR of Half-Integer Quadrupoles towards High Digital-Resolution NMR Spectra
Authors: Yamada Kazuhiko 
Published: August 2017

Abstract
Stepwise-field-swept solid-state nuclear magnetic resonance (NMR) experiments, which potentially make it possible to achieve high digital-resolution NMR spectra, are presented using 79/81Br NMR of strontium bromide hydrate. In contrast to the conventional field-swept NMR in which magnetic fields are continuously varied while FID signals are accumulated, FID signals can be observed with a static magnetic field, and the magnetic fields are stepwise changed after each accumulation. Spectral simulations for the field-swept NMR spectra, calculated by a direct diagonalization method in which the Zeeman and quadrupolar Hamiltonians were numerically diagonalized to obtain transition probabilities, are also described. Improvements necessary to achieve high digital-resolution NMR spectra, including the stability of superconducting magnets and DC power supply sources that control the superconducting magnets in non-persistent mode, are briefly discussed.
The effect of chronic musculoskeletal pain on several quality of life dimensions: A critical review
Authors: Wittkopf Priscilla Geraldine , Zomkowski Kamilla , Cardoso Fernando Luiz , Sperandio Fabiana Flores 
Published: August 2017

Background/Aims: Chronic musculoskeletal pain can lead to disability and affect the emotional health of patients. The aim of this critical review was to analyse the relationship between chronic musculoskeletal pain and different quality of life dimensions. Methods: Electronic databases and reference lists were searched for chronic musculoskeletal pain and quality of life. Titles and abstracts were selected against inclusion criteria. Studies needed to evaluate chronic musculoskeletal pain, have a control group with healthy participants and use only validated instruments to assess pain and quality of life. Findings: Eleven studies were selected and analysed. The majority of studies (54.5%) evaluated fibromyalgia patients and 36% did not specify pain site or musculoskeletal condition. A small number of studies used specific instruments to assess musculoskeletal pain and quality of life. The number of painful areas seems to be related mostly with the emotional and social dimensions, whereas disease severity has more influence on physical and emotional dimensions. Pain chronicity is related to a negative effect on all quality of life dimensions. Conclusions: The relationship between chronic musculoskeletal pain and quality of life can vary according to some aspects, such as the number of painful areas, disease severity and pain chronicity. The reliability of generic instruments to evaluate the quality of life of patients with chronic musculoskeletal pain should be better evaluated.
Inhibition of microRNA-214-5p promotes cell survival and extracellular matrix formation by targeting collagen type IV alpha 1 in osteoblastic MC3T3-E1 cells
Authors: Li Q. S. , Meng F. Y. , Zhao Y. H. , Jin C. L. , Tian J. , Yi X. J. 
Published: August 2017

Objectives This study aimed to investigate the functional effects of microRNA (miR)-214-5p on osteoblastic cells, which might provide a potential role of miR-214-5p in bone fracture healing. Methods Blood samples were obtained from patients with hand fracture or intra-articular calcaneal fracture and from healthy controls (HCs). Expression of miR-214-5p was monitored by qRT-PCR at day 7, 14 and 21 post-surgery. Mouse osteoblastic MC3T3-E1 cells were transfected with antisense oligonucleotides (ASO)-miR-214-5p, collagen type IV alpha 1 (COL4A1) vector or their controls; thereafter, cell viability, apoptotic rate, and the expression of collagen type I alpha 1 (COL1A1), type II collagen (COL-II), and type X collagen (COL-X) were determined. Luciferase reporter assay, qRT-PCR, and Western blot were performed to ascertain whether COL4A1 was a target of miR-214-5p. Results Plasma miR-214-5p was highly expressed in patients with bone fracture compared with HCs after fracture (p < 0.05 or p < 0.01). Inhibition of miR-214-5p increased the viability of MC3T3-E1 cells and the expressions of COL1A1 and COL-X, but decreased the apoptotic rate and COL-II expression (p < 0.05 or p < 0.01). COL4A1 was a target of miR-214-5p, and was negatively regulated by miR-214-5p (p < 0.05 or p < 0.01). Overexpression of COL4A1 showed a similar impact on cell viability, apoptotic rate, and COL1A1, COL-II, and COL-X expressions inhibiting miR-214-5p (p < 0.01). Conclusion Inhibition of miR-214-5p promotes cell survival and extracellular matrix (ECM) formation of osteoblastic MC3T3-E1 cells by targeting COL4A1. Cite this article: Q. S. Li, F. Y. Meng, Y. H. Zhao, C. L. Jin, J. Tian, X. J. Yi. Inhibition of microRNA-214-5p promotes cell survival and extracellular matrix formation by targeting collagen type IV alpha 1 in osteoblastic MC3T3-E1 cells. Bone Joint Res 2017;6:464–471. DOI: 10.1302/2046-3758.68.BJR-2016-0208.R2
Low-temperature pyrolysis of oily sludge: roles of Fe/Al-pillared bentonites
Authors: Jia Hanzhong , Zhao Song , Zhou Xiehong , Qu Chengtun , Fan Daidi , Wang Chuanyi 
Published: August 2017

AbstractPyrolysis is potentially an effective treatment of oily sludge for oil recovery, and the addition of a catalyst is expected to affect its pyrolysis behavior. In the present study, Fe/Al-pillared bentonite with various Fe/Al ratios as pyrolysis catalyst is prepared and characterized by XRD, N2adsorption, and NH3-TPD. The integration of Al and Fe in the bentonite interlayers to form pillared clay is evidenced by increase in the basal spacing. As a result, a critical ratio of Fe/Al exists in the Fe/Al-pillared bentonite catalytic pyrolysis for oil recovery from the sludge. The oil yield increases with respect to increase in Fe/Al ratio of catalysts, then decreases with further increasing of Fe/Al ratio. The optimum oil yield using 2.0 wt% of Fe/Al 0.5-pillared bentonite as catalyst attains to 52.46% compared to 29.23% without catalyst addition in the present study. In addition, the addition of Fe/Al-pillared bentonite catalyst also improves the quality of pyrolysis-produced oil and promotes the formation of CH4. Fe/Al-pillared bentonite provides acid center in the inner surface, which is beneficial to the cracking reaction of oil molecules in pyrolysis process. The present work implies that Fe/Al-pillared bentonite as addictive holds great potential in industrial pyrolysis of oily sludge.
Environmental aspects of using gas chromatography for determination of pharmaceutical residues in samples characterized by different composition of the matrix
Authors: Sadkowska Joanna , Caban Magda , Chmielewski Mariusz , Stepnowski Piotr , Kumirska Jolanta 
Published: August 2017

AbstractThis paper aims at presenting the possibilities of applying gas chromatography for the determination of pharmaceutical residues in different matrices. Section one of the study underscores the environmental advantages of employing GC for such analyses. Section two presents the innovative methods for determining pharmaceuticals in the environment. The last section discusses the results of the analysis of the GC and GC-MS market in Poland.According to the literature data, the described methods were applied for the analysis of real samples: wastewaters, surface waters, soil samples. The samples were collected from the Pomerania region and the Gulf of Gdańsk. The pharmaceuticals were determined in various environmental samples. The highest concentrations were found in raw wastewater, medium – in a treated wastewater, and the lowest – in surface water. The most frequently detected pharmaceuticals were: ibuprofen, paracetamol, diclofenac and naproxen, all belonging to NSAIDs.Furthermore, the results of the study of the Polish GC market indicate that a very limited number of entities are currently using chromatographic techniques, and pharmaceutical residues tests are exceptions, mainly due to the lack of the legal requirements in this field and the lack of own laboratories.