bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of Literacy Instruction That Support Reform in Content Area Classrooms
Authors: Siebert Daniel K. , Draper Roni Jo , Barney Daniel , Broomhead Paul , Grierson Sirpa , Jensen Amy P. , Nielson Jennifer , Nokes Jeffery D. , Shumway Steven , Wimmer Jennifer 
Published: May 2016

AbstractCurrent reforms in content area education present new challenges for literacy educators. These reforms promote engaging students in the practices of the disciplines—teaching students how to participate in an activity in which disciplinary content is produced. Content area literacy (CAL) instruction that supports only the learning of general academic or school literacies undermines these content area reforms and their focus on participation because it does not teach the literacies that students need to participate in the disciplines. In this article, the authors present an argument for why CAL instruction should focus on teaching disciplinary literacies instead of a general academic literacy. The authors show how CAL instruction focused on disciplinary literacies can support the educational goals of both literacy educators and content area reformers. The authors also contrast four corresponding characteristics of both types of CAL instruction and illustrate these with examples.
Helping Students Bridge Inferences in Science Texts Using Graphic Organizers
Authors: Roman Diego , Jones Francesca , Basaraba Deni , Hironaka Stephanie 
Published: May 2016

AbstractThe difficulties that students face when reading science texts go beyond understanding vocabulary and syntactic structures. Comprehension of science texts requires students to infer how these texts function as a unit to communicate scientific meaning. To help students in this process, science texts sometimes employ logical connectives (e.g., because, therefore) that serve as landmarks that students can use to create a mental model of the text. Yet, how often are logical connectives used to mark inferences in science texts, and what can teachers do to support their students when these connectives are absent? This article discusses the frequency and types of logical connectives in four science textbooks and illustrates the types of obstacles that science texts present for students in their inference‐making process. Further, this article offers teachers a practical strategy that they can use to apprentice their students into the ways that science texts function to communicate scientific concepts.
The Safety Behavior Assessment Form: Development and Validation
Authors: Goodson Jason T. , Haeffel Gerald J. , Raush David A. , Hershenberg Rachel 
Published: May 2016

ObjectiveTo develop and validate an easy to administer measure of safety behaviors called the Safety Behavior Assessment Form (SBAF).MethodWe provide reliability and validity evidence from four studies. The first study used a cross‐sectional design with a sample consisting of both clinical (U.S. military Veterans; n = 42) and nonclinical participants (undergraduates; n = 198). Study 2 used a cross‐sectional design with a sample of U.S. military Veterans (n = 215). Study 3 used a pre‐post treatment design with a sample of U.S. military Veterans (n = 42). Study 4 used a 2‐time‐point longitudinal design with a sample of undergraduates (n = 77).ResultsThe SBAF demonstrated strong levels of internal consistency and test‐retest reliability in all four studies. The SBAF also demonstrated predictive and discriminant validity. In Study 3, the SBAF predicted anxious, but not depressive, treatment outcomes in a sample of Veterans. In Study 4, the SBAF predicted prospective changes in anxiety over a 2‐week interval in a sample of undergraduates even after controlling for a competing measure of safety behaviors.ConclusionResults of these four studies indicate that the SBAF is a reliable and valid measure of safety behaviors that can be used in both clinical and nonclinical settings.
Shoshonite-latite series of the Eastern Transbaikalia: 40Ar/39Ar age, geochemistry, and Sr–Nd isotope composition of rocks from the Akatui volcano-plutonic association of the Aleksandrovskii Zavod depression
Authors: Sasim S.A. , Dril S.I. , Travin A.V. , Vladimirova T.A. , Gerasimov N.S. , Noskova Yu.V. 
Published: May 2016

Abstract
The paper presents new data on age, geochemistry, and Sr and Nd isotope composition of rocks from the Akatui massif and comagmatic rocks from the lower unit of the Kailas Formation (Akatui volcano-plutonic association), localized within the Aleksandrovskii Zavod depression. The amphibole 40Ar/39Ar age date the monzogabbro of the early phase of the Akatui massif at 154.8 ± 4.4 Ma; the monzonite of the main phase yields a 40Ar/39Ar age of 160.7 ± 3.9 Ma, and the shoshonite basalt of the lower unit of the Kailas Formation yields a 40Ar/39Ar age of 161.5 ± 1.7 Ma. The leading petrogenetic mechanism for the Akatui volcano-plutonic association is crystal fractional differentiation of melts with minor crustal contamination, which can be suggested from the mineralogical and petrographic features and geochemical and isotope characteristics of rocks. The geochemical data for the Akatui volcano-plutonic association show LILE, LREE, U, Th, and Pb enrichment with a characteristic depletion in high-field strength elements (HFSE), such as Nb and Ti. They are also depleted in P. Sr–Nd isotope data (87Sr/86Sr(160 Ma) = 0.70642–0.70688 and εNd(160 Ma) = – 0.6 to – 2.2) suggest an EMII-type mantle source and could also indicate a negligible degree of crustal contamination in the evolved melts.
Tectonic activity of the early Earth (4.56–3.4(2.7?) Ga)
Authors: Kuzmin M.I. , Yarmolyuk V.V. , Ernst R.E. 
Published: May 2016

Abstract
The paper discusses a possible model of the ancient (Hadean–Archean) Earth’s geodynamic evolution. We believe that the early Earth was characterized by a stagnant lid regime and whole-mantle convection suggesting cells that convect through the whole mantle (from the core–mantle boundary to the lithosphere base). The lid tectonics was perturbed by asteroid–meteorite bombardments that destroyed the primary terrestrial partly granitoid crust. The destroyed crust together with the residual enriched mantle reservoirs sank into the lower mantle. In addition to the crust destruction, the bombardments led to emplacement of a huge proportion of basalt-komatiitic melts, which can be interpreted as mantle overturn events. In the Hadean, the Earth survived frequent large-scale asteroid–meteorite bombardments, which resulted in almost a complete destruction of the primary terrestrial crust. In the Early Archean, the Earth still experienced the same tectonic processes, as in the Hadean; however, meteorite impact was small-scale and the bombardments influenced only a limited area of a common, as it seems to us, subequatorial supercontinent. Those bombardments led to the sagduction of the Archean basalt–komatiiic terrestrial crust, which sank into the mantle, transforming into amphibolite–eclogite rocks giving rise to a tonalite–troondhjemite–granodiorite suite. As preserved in the zircon record, the formation of the Archean mantle-derived magmas occurred as pulses at 4.5, 4.2–4.3, 3.8–3.9, and 3.3–3.4 Ga. These peaks, most likely, correspond to the Hadean–Archean meteorite bombardments. There is evidence of formation of the subcontinental lithospheric mantle (SCLM) beneath the cratons between 3.3 and 3.5 Ga. This SCLM was markedly different from peridotites of modern ophiolites. However, the existence of ophiolitic peridotites indicates that modern style plate tectonic processes were in operation at that time, as we will discuss below. The transition from the early Earth (Hadean–Archean) tectonic style to the recent tectonics occurred between 3.4 (2.7?) and 2.0 Ga.
Impact of projected mid-21st century climate and soil extrapolation on simulated spring wheat grain yield in Southeastern Norway
Authors: PERSSON T. , KVÆRNØ S. 
Published: May 2016

SUMMARYThe effects of soil variability on regional crop yield under projected climate change are largely unknown. In Southeastern Norway, increased temperature and precipitation are projected for the mid-21st century. Crop simulation models in combination with scaling techniques can be used to determine the regional pattern of crop yield. In the present paper, the CSM-CROPSIM-CERES-Wheat model was applied to simulate regional spring wheat yield for Akershus and Østfold counties in Southeastern Norway. Prior to the simulations, parameters in the CSM-CROPSIM-CERES-Wheat model were calibrated for the spring wheat cvars Zebra, Demonstrant and Bjarne, using cultivar trial data from Southeastern Norway and site-specific weather and soil information. Weather input data for regional yield simulations represented the climate in 1961–1990 and projections of the climate in 2046–2065. The latter were based on four Global Climate Models and greenhouse gas emission scenario A1B in the IPCC 4th Assessment Report. Data on regional soil particle size distribution, water-holding characteristics and organic matter data were obtained from a database. To determine the simulated grain yield sensitivity to soil input, the number of soil profiles used to describe the soilscape in the region varied from 76 to 16, 5 and 1. The soils in the different descriptions were selected by arranging them into groups according to similarities in physical characteristics and taking the soil in each group occupying the largest area in the region to represent other soils in that group. The simulated grain yields were higher under all four projected future climate scenarios than the corresponding average yields in the baseline conditions. On average across the region, there were mostly non-significant differences in grain yield between the soil extrapolations for all cultivars and climate projections. However, for sub-regions grain yield varied by up to 20% between soil extrapolations. These results indicate how projected climate change could affect spring wheat yield given the assumed simulated conditions for a region with similar climate and soil conditions to many other cereal production regions in Northern Europe. The results also provide useful information about how soil input data could be handled in regional crop yield determinations under these conditions.
Morphological description and molecular analyses ofTylodelphyssp. (Trematoda: Diplostomidae) newly recorded from the freshwater fishGobiomorphus cotidianus(common bully) in New Zealand
Authors: Blasco-Costa I. , Poulin R. , Presswell B. 
Published: May 2016

AbstractAmong eyeflukes,TylodelphysDiesing, 1850 includes diverse species able to infect the eyes, but also the brain, pericardial sac and body cavity of their second intermediate host. While the genus shows a cosmopolitan distribution with 29 nominal species in Africa, Asia, Europe and America, a likely lower research effort has produced two records only for all of Australasia. This study provides the first description of a species ofTylodelphysand the first record for a member of the Diplostomidae in New Zealand.Tylodephyssp. metacercaria from the eyes ofGobiomorphus cotidianusMcDowall, 1975 is distinguished from its congeners as being larger in all, or nearly all, metrics thanTylodelphys clavata(von Nordmann, 1832),T. conifera(Mehlis, 1846) andT. scheuringi(Hughes, 1929); whereasT. podicipinaKozicka & Niewiadomska, 1960 is larger in body size, ventral sucker and holdfast sizes andT. ophthalmi(Pandey, 1970) has comparatively a very small pharynx and body spination.Tylodelphyssp. exhibits consistent genetic variation for the 28S rDNA, internal transcribed spacer (ITS) andCox1 genes, and phylogenetic analyses confirm that it represents an independent lineage, closely related to North American species. Morphological and molecular results together support the distinct species status ofTylodephyssp. metacercaria, the formal description and naming of which await discovery of the adult. Furthermore, the validity ofT. strigicolaOdening, 1962 is restored,T. cerebralisChakrabarti, 1968 is proposed as major synonym ofT. ophthalmi, and species described solely on the basis of metacercariae are consideredincertae sedis,except those for which molecular data already exist.
The coevolution of recognition and social behavior
Authors: Smead Rory , Forber Patrick 
Published: May 2016

AbstractRecognition of behavioral types can facilitate the evolution of cooperation by enabling altruistic behavior to be directed at other cooperators and withheld from defectors. While much is known about the tendency for recognition to promote cooperation, relatively little is known about whether such a capacity can coevolve with the social behavior it supports. Here we use evolutionary game theory and multi-population dynamics to model the coevolution of social behavior and recognition. We show that conditional harming behavior enables the evolution and stability of social recognition, whereas conditional helping leads to a deterioration of recognition ability. Expanding the model to include a complex game where both helping and harming interactions are possible, we find that conditional harming behavior can stabilize recognition and thereby lead to the evolution of conditional helping. Our model identifies a novel hypothesis for the evolution of cooperation: conditional harm may have coevolved with recognition first, thereby helping to establish the mechanisms necessary for the evolution of cooperation.
The Evx1/Evx1as gene locus regulates anterior-posterior patterning during gastrulation
Authors: Bell Charles C. , Amaral Paulo P. , Kalsbeek Anton , Magor Graham W. , Gillinder Kevin R. , Tangermann Pierre , di Lisio Lorena , Cheetham Seth W. , Gruhl Franziska , Frith Jessica , Tallack Michael R. , Ru Ke-Lin , Crawford Joanna , Mattick John S. , Dinger Marcel E. , Perkins Andrew C. 
Published: May 2016

AbstractThousands of sense-antisense mRNA-lncRNA gene pairs occur in the mammalian genome. While there is usually little doubt about the function of the coding transcript, the function of the lncRNA partner is mostly untested. Here we examine the function of the homeotic Evx1-Evx1as gene locus. Expression is tightly co-regulated in posterior mesoderm of mouse embryos and in embryoid bodies. Expression of both genes is enhanced by BMP4 and WNT3A, and reduced by Activin. We generated a suite of deletions in the locus by CRISPR-Cas9 editing. We show EVX1 is a critical downstream effector of BMP4 and WNT3A with respect to patterning of posterior mesoderm. The lncRNA, Evx1as arises from alternative promoters and is difficult to fully abrogate by gene editing or siRNA approaches. Nevertheless, we were able to generate a large 2.6 kb deletion encompassing the shared promoter with Evx1 and multiple additional exons of Evx1as. This led to an identical dorsal-ventral patterning defect to that generated by micro-deletion in the DNA-binding domain of EVX1. Thus, Evx1as has no function independent of EVX1, and is therefore unlikely to act in trans. We predict many antisense lncRNAs have no specific trans function, possibly only regulating the linked coding genes in cis.
Improved intra-array and interarray normalization of peptide microarray phosphorylation for phosphorylome and kinome profiling by rational selection of relevant spots
Authors: Scholma Jetse , Fuhler Gwenny M. , Joore Jos , Hulsman Marc , Schivo Stefano , List Alan F. , Reinders Marcel J. T. , Peppelenbosch Maikel P. , Post Janine N. 
Published: May 2016

AbstractMassive parallel analysis using array technology has become the mainstay for analysis of genomes and transcriptomes. Analogously, the predominance of phosphorylation as a regulator of cellular metabolism has fostered the development of peptide arrays of kinase consensus substrates that allow the charting of cellular phosphorylation events (often called kinome profiling). However, whereas the bioinformatical framework for expression array analysis is well-developed, no advanced analysis tools are yet available for kinome profiling. Especially intra-array and interarray normalization of peptide array phosphorylation remain problematic, due to the absence of “housekeeping” kinases and the obvious fallacy of the assumption that different experimental conditions should exhibit equal amounts of kinase activity. Here we describe the development of analysis tools that reliably quantify phosphorylation of peptide arrays and that allow normalization of the signals obtained. We provide a method for intraslide gradient correction and spot quality control. We describe a novel interarray normalization procedure, named repetitive signal enhancement, RSE, which provides a mathematical approach to limit the false negative results occuring with the use of other normalization procedures. Using in silico and biological experiments we show that employing such protocols yields superior insight into cellular physiology as compared to classical analysis tools for kinome profiling.
Quantization Effects on Complex Networks
Authors: Wang Ying , Wang Lin , Yang Wen , Wang Xiaofan 
Published: May 2016

AbstractWeights of edges in many complex networks we constructed are quantized values of the real weights. To what extent does the quantization affect the properties of a network? In this work, quantization effects on network properties are investigated based on the spectrum of the corresponding Laplacian. In contrast to the intuition that larger quantization level always implies a better approximation of the quantized network to the original one, we find a ubiquitous periodic jumping phenomenon with peak-value decreasing in a power-law relationship in all the real-world weighted networks that we investigated. We supply theoretical analysis on the critical quantization level and the power laws.
Nonalcoholic Fatty Liver Disease is Associated with Increased Carotid Intima-Media Thickness in Type 1 Diabetic Patients
Authors: Zhang Lei , Guo Kaifeng , Lu Junxi , Zhao Fangya , Yu Haoyong , Han Junfeng , Bao Yuqian , Chen Haibing , Jia Weiping 
Published: May 2016

AbstractA growing body of evidence suggests that NAFLD is associated with an increased risk of incident CVD events both in patients without diabetes and in those with type 2 diabetes (T2DM). However, no published data are available regarding the association between NAFLD and C-IMT in T1DM. A total of 722 patients (371 men) with T1DM were included in this cross-sectional study. The main outcome measures were detection of NAFLD, C-IMT and classical risk factors. The mean age of the subjects was 46.2 years, and 51.1% were male. The prevalence of NAFLD was 15.9%. NAFLD patients had a markedly greater C-IMT (0.81 ± 0.25 vs. 0.69 ± 0.18 mm; p < 0.001) and frequency of carotid plaque (28.9% vs. 16.9%; p < 0.05) than those without fatty liver. Moreover, the differences in C-IMT remained after adjusting for potential confounders. A stepwise linear regression analysis revealed that age (standardized β, 0.326; p < 0.001), NAFLD (standardized β, 0.151, p < 0.001), and hsCRP (standardized β, 0.115, p = 0.008) were independently associated with C-IMT in all subjects. Our data show NAFLD is associated with elevated C-IMT in T1DM independent of conventional cardiovascular disease risk factors.
Strongly Modulated Friction of a Film-Terminated Ridge-Channel Structure
Authors: He Zhenping , Hui Chung-Yuen , Levrard Benjamin , Bai Ying , Jagota Anand 
Published: May 2016

AbstractNatural contacting surfaces have remarkable surface mechanical properties, which has led to the development of bioinspired surface structures using rubbery materials with strongly enhanced adhesion and static friction. However, sliding friction of structured rubbery surfaces is almost always significantly lower than that of a flat control, often due to significant loss of contact. Here we show that a film-terminated ridge-channel structure can strongly enhance sliding friction. We show that with properly chosen materials and geometrical parameters the near surface structure undergoes mechanical instabilities along with complex folding and sliding of internal interfaces, which is responsible for the enhancement of sliding friction. Because this structure shows no enhancement of adhesion under normal indentation by a sphere, it breaks the connection between energy loss during normal and shear loading. This makes it potentially interesting in many applications, for instance in tires, where one wishes to minimize rolling resistance (normal loading) while maximizing sliding friction (shear loading).
CRISPR/Cas9-Mediated Immunity to Geminiviruses: Differential Interference and Evasion
Authors: Ali Zahir , Ali Shakila , Tashkandi Manal , Zaidi Syed Shan-e-Ali , Mahfouz Magdy M. 
Published: May 2016

AbstractThe CRISPR/Cas9 system has recently been used to confer molecular immunity against several eukaryotic viruses, including plant DNA geminiviruses. Here, we provide a detailed analysis of the efficiencies of targeting different coding and non-coding sequences in the genomes of multiple geminiviruses. Moreover, we analyze the ability of geminiviruses to evade the CRISPR/Cas9 machinery. Our results demonstrate that the CRISPR/Cas9 machinery can efficiently target coding and non-coding sequences and interfere with various geminiviruses. Furthermore, targeting the coding sequences of different geminiviruses resulted in the generation of viral variants capable of replication and systemic movement. By contrast, targeting the noncoding intergenic region sequences of geminiviruses resulted in interference, but with inefficient recovery of mutated viral variants, which thus limited the generation of variants capable of replication and movement. Taken together, our results indicate that targeting noncoding, intergenic sequences provides viral interference activity and significantly limits the generation of viral variants capable of replication and systemic infection, which is essential for developing durable resistance strategies for long-term virus control.
Adolescent context of exposure to prescription opioids and substance use disorder symptoms at age 35: a national longitudinal study
Authors: McCabe Sean Esteban , Veliz Philip , Schulenberg John E. 
Published: May 2016

Abstract
The objective of this study was to examine the association of context of prescription opioid exposure (ie, medical or nonmedical) in adolescence with the subsequent risk of nonmedical use of prescription opioids (NMUPO) and substance use disorder (SUD) symptoms at age 35. Multiple cohorts of nationally representative probability samples of U.S. high school seniors (n = 4072) were surveyed through self-administered questionnaires and followed longitudinally from adolescence (modal age 18, graduating classes 1976-1996) to age 35 (1993-2013). Main outcome measures were past-year NMUPO and SUD symptoms. The medical and NMUPO during adolescence was significantly associated with NMUPO at age 35. Relative to no prescription opioid exposure, medical use of prescription opioids without any history of NMUPO during adolescence was not associated with SUD symptoms at age 35. In contrast, compared with no prescription opioid exposure during adolescence, the adjusted odds ratios (AORs) associated with SUD symptoms at age 35 were greater among those with a history of both medical use of prescription opioids and NMUPO during adolescence, AOR = 1.49 (95% CI = 1.13-1.97); and among those who reported NMUPO only, AOR = 2.61 (95% CI = 1.88-3.61). The findings indicate medical use of prescription opioids without any history of NMUPO in adolescence is not associated with SUD symptoms at age 35, whereas any NMUPO in adolescence predicts SUD symptoms at age 35. Screening instruments and preventive intervention programs to reduce NMUPO and SUDs must account for the context associated with prescription opioid exposure during adolescence.