bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors associated with multi-drug-resistant Acinetobacter baumannii nosocomial infections at a tertiary care hospital in Makkah, Saudi Arabia - a matched case–control study
Authors: Al-Gethamy Manal M , Faidah Hani S , Adetunji Hamed Ademola , Haseeb Abdul , Ashgar Sami S , Mohanned Tayeb K , Mohammed Al-Haj , Khurram Muhammad , Hassali Mohamed A 
Published: May 2017

Objective To determine risk factors for multi-drug-resistant Acinetobacter baumannii (MDR-AB) nosocomial infections in intensive care units in a tertiary care hospital, Makkah, Saudi Arabia. Methods We performed a hospital-based, matched case–control study in patients who were admitted to Al Noor Specialist Hospital between 1 January 2012 and 31 August 2012. The study included cases of A. baumannii nosocomial infection and controls without infection. Controls were matched to cases by age and ward of admission. Results The most frequent site of infection was the respiratory tract (77.3%). Susceptibility to antimicrobial MDR-AB was 92.0% for ceftazidime and ciprofloxacin, while it was 83.3% for imipenem, 83.0% for trimethoprim, 79.0% for amikacin, and 72.7% for gentamicin. Multiple logistic regression of risk factors showed that immunosuppression (OR = 2.9; 95% CI 1.5–5.6; p = 0.002), clinical outcome (OR = 0.4; 95% CI 0.3–0.9; p = 0.01), invasive procedures (OR = 7.9; 95% CI 1.8–34.2; p = 0.002), a central venous catheter (OR = 2.9; 95% CI 1.5–5.6; p = 0.000), and an endotracheal tube (OR = 3.4; 95% CI 1.6–7.3; p = 0.001) were associated with MDR-AB. Conclusions Acinetobacter nosocomial infections are associated with admission to the ICU (Intensive care unit) and exposure to invasive procedures.
Hallux Valgus Correction Comparing Percutaneous Chevron/Akin (PECA) and Open Scarf/Akin Osteotomies
Authors: Lee Moses , Walsh James , Smith Margaret M. , Ling Jeff , Wines Andrew , Lam Peter 
Published: May 2017

Background: Minimally invasive surgery is being used increasingly, including for hallux valgus surgery. Despite the growing interest in minimally invasive procedures, there have been few publications on percutaneous chevron/akin (PECA) procedures, and no studies have been published comparing PECA to open scarf/akin osteotomies (SA). Methods: This was a prospective, randomized study of 50 patients undergoing operative correction of hallux valgus using one of 2 techniques (PECA vs open SA). Data were collected preoperatively and on 1 day, 2 weeks, 6 weeks, and 6 months postoperatively. Outcome measures include the American Orthopaedic Foot & Ankle Society Hallux-Metatarsophalangeal-Interphalangeal (AOFAS-HMI) Score, visual analog pain score, hallux valgus angle (HVA), and 1-2 intermetatarsal angle (IMA). Twenty-five patients underwent PECA procedures and 25 patients received SA procedures. Results: Both groups showed significantly improved AOFAS-HMI scores after surgery (PECA group: 61.8 to 88.9, SA group: 57.3 to 84.1, P = .560) with comparable final scores. HVA and IMA also presented similar outcomes at final follow-up ( P = .520 and P = .270, respectively). However, the PECA group showed significantly lower pain level (VAS) in the early postoperative phase (postoperative day 1 to postoperative week 6, P < .001 and P = .004, respectively). No serious complications were observed in either group. Conclusion: Both groups showed comparable good to excellent clinical and radiologic outcomes at final follow-up. However, the PECA group had significantly less pain in the first 6 weeks following surgery. Level of Evidence Level II, prospective comparative study.
Clinically significant depressive symptoms and sexual behaviour among men who have sex with men
Authors: Miltz Ada R. , Rodger Alison J. , Sewell Janey , Speakman Andrew , Phillips Andrew N. , Sherr Lorraine , Gilson Richard J. , Asboe David , Nwokolo Nneka C. , Clarke Amanda , Gompels Mark M. , Allan Sris , Collins Simon , Lampe Fiona C. ,   for the AURAH Study Group
Published: May 2017

BackgroundThe relationship between depression and sexual behaviour among men who have sex with men (MSM) is poorly understood.AimsTo investigate prevalence and correlates of depressive symptoms (Patient Health Questionnaire-9 score ≥10) and the relationship between depressive symptoms and sexual behaviour among MSM reporting recent sex.MethodThe Attitudes to and Understanding of Risk of Acquisition of HIV (AURAH) is a cross-sectional study of UK genitourinary medicine clinic attendees without diagnosed HIV (2013–2014).ResultsAmong 1340 MSM, depressive symptoms (12.4%) were strongly associated with socioeconomic disadvantage and lower supportive network. Adjusted for key sociodemographic factors, depressive symptoms were associated with measures of condomless sex partners in the past 3 months (≥2 (prevalence ratio (PR) 1.42, 95% CI 1.17–1.74; P=0.001), unknown or HIV-positive status (PR 1.43, 95% CI 1.20–1.71; P<0.001)), sexually transmitted infection (STI) diagnosis (PR 1.46, 95% CI 1.19–1.79; P<0.001) and post-exposure prophylaxis use in the past year (PR 1.83, 95% CI 1.33–2.50; P<0.001).ConclusionsManagement of mental health may play a role in HIV and STI prevention.
Chromatin organization at the nuclear periphery as revealed by image analysis of structured illumination microscopy data
Authors: Fišerová Jindřiška , Efenberková Michaela , Sieger Tomáš , Maninová Miloslava , Uhlířová Jana , Hozák Pavel 
Published: May 2017

ABSTRACT
The nuclear periphery (NP) plays a substantial role in chromatin organization. Heterochromatin at the NP is interspersed with active chromatin surrounding nuclear pore complexes (NPCs); however, details of the peripheral chromatin organization are missing. To discern the distribution of epigenetic marks at the NP of HeLa nuclei, we used structured illumination microscopy combined with a new MATLAB software tool for automatic NP and NPC detection, measurements of fluorescent intensity and statistical analysis of measured data. Our results show that marks for both active and non-active chromatin associate differentially with NPCs. The incidence of heterochromatin marks, such as H3K27me2 and H3K9me2, was significantly lower around NPCs. In contrast, the presence of marks of active chromatin such as H3K4me2 was only decreased very slightly around the NPCs or not at all (H3K9Ac). Interestingly, the histone demethylases LSD1 (also known as KDM1A) and KDM2A were enriched within the NPCs, suggesting that there was a chromatin-modifying mechanism at the NPCs. Inhibition of transcription resulted in a larger drop in the distribution of H1, H3K9me2 and H3K23me2, which implies that transcription has a role in the organization of heterochromatin at the NP.
Reductive Approach to Nitrones from N-Siloxyamides and N-Hydroxyamides
Authors: Katahara Seiya , Kobayashi Shoichiro , Fujita Kanami , Matsumoto Tsutomu , Sato Takaaki , Chida Noritaka 
Published: May 2017

Abstract
This article describes the full details of our reductive approach to nitrones from amides. Reduction of N-siloxyamides with the Schwartz reagent [Cp2ZrHCl], followed by addition of an acid provided functionalized nitrones. The developed conditions were then extended to a catalytic version with the Vaska complex [IrCl(CO)(PPh3)2] and (Me2HSi)2O starting from N-hydroxyamides. 1H NMR studies of the Ir-catalyzed reaction revealed that the developed conditions promoted two different types of catalytic reactions including dehydrosilylation of an N-hydroxyl group and subsequent hydrosilylation of an amide carbonyl. A salient feature of our methods is their high chemoselectivity in the presence of a variety of functional groups. In addition, our reductive methods enabled concise synthesis of cyclic and macrocyclic nitrones, which are known to be challenging compounds to access by conventional methods.
Conservative management strategies and stress level in children and adolescents with idiopathic scoliosis
Authors: Zimoń Michalina , Matusik Edyta , Kapustka Bartosz , Durmała Jacek , Doroniewicz Iwona , Wnuk Bartosz 
Published: May 2017

Cel pracyCelem pracy była ocena poziomu stresu u dzieci i młodzieży ze skoliozą idiopatyczną (SI), leczonych zachowawczo metodą Dobosiewicz (DoboMed), w korelacji do parametrów klinicznych i konieczności stosowania terapii za pomocą gorsetu.MetodaGrupę badaną (GB) stanowiło 63 pacjentów (54 dziewczęta) o średniej wieku 14,7 lat. Wszyscy objęci badaniem byli leczeni metodą DoboMed, a 31 pacjentów stosowało także gorset (ortozę). W analizie wzięto pod uwagę stan odżywienia (BMI Z-score) pacjentów, wiek diagnozy, lokalizację skrzywienia oraz czas noszenia gorsetu. Poziom stresu analizowano dwukrotnie (kwestionariusze Bad Sobernheim Questionnaire Deformity (BSSQ-Deformity) oraz Bad Sobernheim Questionnaire Brace (BSSQ-Brace)) na początku i na końcu hospitalizacji.WynikiWiększość dzieci i młodzież z SI leczonych metodą DoboMed odczuwa niski lub średni poziom stresu związany z deformacją kręgosłupa (odpowiednio 58,7% i 36,5%). Znamiennie wyższy poziom stresu (BSSQ-Deformity) stwierdzono w grupie leczonej gorsetem w odniesieniu do grupy leczonej tylko za pomocą kinezyterapii (p<0,05). Pacjenci leczeni gorsetowo prezentowali znamiennie wyższy poziom stresu związany z noszeniem ortozy, niż z samą deformacją kręgosłupa (p<0,0001). Poziom stresu (BSSQ-Deformity) korelował znamiennie z wiekiem chorych, BMI Z-score i liczbą przebytych hospitalizacji (p<0,05). Poziom stresu związany z deformacją był znamiennie zależny od wielkości kąta skrzywienia (kąt Cobb’a) w obu analizowanych podgrupach.WnioskiPoziom stresu pacjentów z SI jest związany ze stopniem nasilenia schorzenia, niezależnie od metody leczenia. Terapia gorsetowa jest czynnikiem indukującym i nasilającym stres. Poziom stresu związanego z gorsetowaniem, przewyższa stres związany z deformacją kręgosłupa. Inne czynniki wpływające na poziom stresu to wiek, stan odżywienia i liczba hospitalizacji. Kompleksowe leczenie powinno obejmować także opiekę psychologiczną młodych pacjentów z SI.
The Polish adaptation of the Life Events Checklist (LEC-5) for PTSD criteria from DSM-5
Authors: Rzeszutek Marcin , Lis-Turlejska Maja , Palich Hanna , Szumiał Szymon 
Published: May 2017

Cel pracyCelem niniejszej pracy była prezentacja wyników badań empirycznych nad polską adaptacją kwestionariusza Life Events Checklist do DSM-5 (LEC-5) służącego do pomiaru ekspozycji na traumatyczne zdarzenia według definicji zaburzenia po stresie traumatycznym (ang. posttraumatic stress disorder, PTSD) w DSM-5.MetodaW badaniu uczestniczyło 172 studentów Wyższej Szkoły Finansów i Zarządzania w Warszawie (WSFiZ), w tym 68 kobiet i 104 mężczyzn w wieku 17–49 lat (M=22,74; SD=6,80). Rzetelność kwestionariusza LEC-5 mierzono metodą stabilności bezwzględnej. Powtórny pomiar zrealizowano po upływie dwóch tygodni w próbie 40 studentów WSFiZ. Trafność pomiaru weryfikowano poprzez analizę korelacji pomiędzy skalami kwestionariusza LEC-5 i skalami kwestionariusza Skali Samooceny PTSD według kryteriów DSM-5 (ang. PTSD Diagnostic Scale for DSM-5; PDS-5) i Skali Wpływu Zdarzeń (ang. Impact of Events Scale; IES) w całej próbie 172 studentów WSFiZ.WynikiWartości współczynników korelacji wewnątrzklasowej otrzymane dla wszystkich skal LEC-5 oraz wartości miar zgodności kappa Cohena oznaczały bardzo wysoką stabilność pomiaru. Uzyskano również istotne korelacje pomiędzy skalami kwestionariusza LEC-5, skalami kwestionariusza PDS-5 i IES wskazujące na trafność zaadaptowanego przez autorów narzędzia.WnioskiUzyskane przez autorów rezultaty potwierdzają zadowalające własności psychometryczne zaadaptowanego narzędzia LEC-5.
KESETIMBANGAN ADSORBSI SENYAWA ORGANIK VOLATIL PADA PERMUKAAN TANAH (SUATU PREDIKSI MODEL)
Authors: Hargono Hargono 
Published: May 2017

Model adsorbsi klasik Langmuir dan BET (Brauer-Emmet-Teller) memberikan titik awal dalam pengembangan model mengenai "equilibrium state" senyawa organik volatil pada permukaan tanah. Moisture content (kandungan air) dalam tanah merupakan faktor kunci (key factor) peristiwa adsorpsi. Prediksi model persamaan diberlakukan untuk tanah kering , lembab dan basah. Pada keseimbangan adsorpsi senyawa organik volatil di udara dan di tanah memberikan korelasi antara konsentrasi uap senyawa organik volatil dikorelasikan dengan moisture content tanah. Teori menunjukkan 3 sub model tanah yang paling dominan adalah adsorpsi yang dilakukan oleh tanah kering (dry soils).
PENENTUAN ENERGI AKTIVASI PEMBAKARAN BRIKET CHAR SAMPAH KOTA DENGAN MENGGUNAKAN METODA THERMOGRAVIMETRY DAN ISOTHERMAL FURNACE
Authors: Himawanto Dwi Aries 
Published: May 2017

Penelitian ini bertujuan mencari energi aktivasi pembakaran briket char sampah kota dengan metoda thermogravimetry dan isothermal furnace. Penelitian diawali dengan pembuatan briket char dengan komposisi 75 % sampah organik dan 25 % yang dilakukan dengan jalan ditekan dalam sebuah mesin pres hingga berbentuk silindris, dengan tekanan pengepresan 250 kg/cm2 dan lama holding time (penahanan tekanan) selama 1 menit. Briket arang sampah kota tersebut dibuat dengan menggunakan perekat tepung kanji dengan berat 20 % dari berat total briket. Berat sampel briket char sampah kota adalah seberat 3 gram. Selanjutnya dilakukan uji laju pembakaran dengan menggunakan dua metode, metode pertama adalah metode thermogravimetry yang dilakukan dengan cara menaikkan temperatur ruang bakar dari temperatur kamar secara bertahap dengan besar kenaikan konstan tiap waktu sebesar 20 0C/menit, sampai sampel bahan bakar terbakar habis, sementara metode yang kedua adalah metode isothermal furnace, dimana briket char sampah akan diletakkan dalam reaktor dengan temperatur ruang tertentu sampai terbakar habis, variasi temperatur ruang bakar yang dipilih adalah 250 0C, 500 0C dan 600 0C . Pada pengujian pembakaran secara isothermal furnace dilakukan pada kecepatan aliran udara 0,1 m/s . Hasil penelitian menunjukkan bahwa metoda isothermal furnace dapat digunakan untuk melakukan perhitungan energi aktivasi pembakaran seperti halnya metoda thermogravimetry, dengan memperhatikan pemilihan suhu reaktor yang dipilih, banyaknya kondisi isothermal yang digunakan serta sifat-sifat fisis dari briket
PENGARUH WAKTU DAN TEMPERATUR SINTER TERHADAP DENSITAS DAN POROSITAS KOMPOSIT ALUMINIUM YANG DIPERKUAT LIMBAH GEOTHERMAL
Authors: Sulardjaka Sulardjaka , Rahman M.S. , Wahyudianto C. 
Published: May 2017

Pembuangan limbah geothermal ke lingkungan akan mengakibatkan masalah pencemaran lingkungan. Untuk mengatasi masalah pembuangan limbah geothermal ke lingkungan, perlu dilakukan upaya untuk memanfaakan limbah geothermal tersebut. Pada penelitian ini memanfaatkan limbah geothermal sebagai penguat pada bahan komposit matrik aluminium. Proses pembuatan komposit dilakukan dengan metode metalurgi serbuk. Pembuatan green body komposit dilakukan dengan penekanan secara uniaxial dengan tekanan kompaksi 250 MPa. Sintering dilakukan di dalam dapur elektrik pada lingkungan gas argon dengan variasi temperatur sinter 550 oC, 550 oC dan 600 oC dengan waktu penahanan sinter 1, 2 dan 4 jam. Pengujian terhadap densitas dilakukan berdasarkan hukum Archimedes. Porositas bahan komposit dihitung dengan membandingkan densitas hasil pengukuran dengan densitas teoritis.
PENGARUH TEKSTUR PERMUKAAN MATERIAL UHMWPE TERHADAP DISTRIBUSI TEGANGAN PADA BEBAN KONTAK STATIC, ROLLING DAN SLIDING
Authors: Jamari Jamari , Priyoga Fajar Hari 
Published: May 2017

Material UHMWPE (Ultra High Molecular Weight Polyethylene) sering digunakan sebagai actebular liner pada sistem sambungan tulang panggul buatan. Fungsi material ini sebagai bantalan dan peredam. Performansi material ini terus dikaji dan ditingkatkan melalui berbagai macam teknologi. Optimasi bentuk tekstur merupakan salah satu cara dalam meningkatkan karakteristik tribologi. Paper ini bertujuan mengkaji pengaruh tekstur permukaan terhadap distribusi tegangan von Mises untuk beban statik, roling dan sliding. Perhitungan tegangan dan distribusinya dilakukan mengunakan metode elemen hingga. Hasil menunjukkan bahwa untuk semua kasus pembebanan baik statik, roling maupun sliding tegangan von Mises yang terbesar terjadi pada tekstur permukaan yang memiliki diameter lubang (cavities) yang terkecil. Selain itu besarnya tegangan maksimum von Mises paling besar terjadi pada kasus beban kontak sliding kemudian kontak roling dan yang paling kecil kontak statik.
Fin junction of ferroelectric thin films
Authors: Carbone Luciano , Chacouche Khaled , Gaudiello Antonio 
Published: May 2017

Abstract
In this paper, starting from a non-convex and nonlocal 3D-variational
model for the electric polarization in a ferroelectric material, and using an asymptotic process based on dimensional reduction,
we analyze junction phenomena for two orthogonal joined ferroelectric thin films. We obtain three different 2D-variational models for joined thin films, depending on how the reduction happens. Indeed, a memory effect of the reduction process appears, and it depends on the competition of the relative thickness of the two films. The guide parameter is the limit of the ratio between these two small thickness.
A new method for converting boundary value problems for impulsive fractional differential equations to integral equations and its applications
Authors: Liu Yuji 
Published: May 2017

Abstract
In this paper, we present a new method for converting boundary value problems of impulsive fractional differential equations to integral equations. Applications of this method are given to solve some types of anti-periodic boundary value problems for impulsive fractional differential equations. Firstly by using iterative method, we prove existence and uniqueness of solutions of Cauchy problems of differential equations involving Caputo fractional derivative, Riemann–Liouville and Hadamard fractional derivatives with order

q
∈

(
0
,
1
)

{q\in(0,1)}

, see Theorem 2, Theorem 4, Theorem 6 and Theorem 8. Then we obtain exact expression of piecewise continuous solutions of these fractional differential equations see Theorem 1, Theorem 2, Theorem 3 and Theorem 4. Finally, four classes of integral type anti-periodic boundary value problems of singular fractional differential equations with impulse effects are proposed.
Sufficient conditions are given for the existence of solutions of these problems. See Theorems 4.1–4.4. We allow the nonlinearity

p
⁢

(
t
)

⁢
f
⁢

(
t
,
x
)

{p(t)f(t,x)}

in fractional differential equations to be singular at

t
=

0
,
1

{t=0,1}

and be involved a super-linear and sub-linear term. The analysis relies on Schaefer’s fixed point theorem. In order to avoid misleading readers, we correct the results in [28] and [65]. We establish sufficient conditions for the existence of solutions of an anti-periodic boundary value problem for impulsive fractional differential equation. The results in [68] are complemented. The results in [81] are corrected. See Lemma 5.1, Lemma 5.7, Lemma 5.10 and Lemma 5.13.
Influence of age, gender and body mass index on late-night salivary cortisol in healthy adults
Authors: Coelli Sabrina , Farias Camila Bergonsi , Soares Ariana Aguiar , Crescente Gabriele Martins , Hirakata Vânia Naomi , Souza Luiza Barboza , Czepielewski Mauro Antônio , Camargo Joíza Lins , Silveiro Sandra Pinho 
Published: May 2017

AbstractBackground:Late-night salivary cortisol (LNSC) is one of the most reliable tests to screen for endogenous Cushing syndrome. This test is simple, inexpensive and noninvasive and has high sensitivity and specificity. The aim of our study was to analyze the putative influence of age, gender and body mass index (BMI) on LNSC levels in a healthy population.Methods:Cross-sectional study conducted in healthy adults. Midnight saliva samples were collected at home. Participants refrained from teeth brushing, eating or drinking for 2 h prior to collection. Salivary cortisol measured by electrochemiluminescence immunoassay (ECLIA). The study was approved by the Ethics Committee of the hospital (number 140073).Results:We evaluated 122 nonsmoking healthy volunteers. Mean age was 35±14 years (range, 18–74 years); 63% were women. Mean BMI was 24±3 kg/mConclusions:The maximum reference value (P97.5) of LNSC was set at 8.3 nmol/L (0.3 μg/dL) using ECLIA. Advanced age was associated with higher LNSC levels, with no evident influence of gender or BMI.
Intensive educational efforts combined with external quality assessment improve the preanalytical phase in general practitioner offices and nursing homes
Authors: Sølvik Una Ørvim , Bjelkarøy Wenche Iren , Berg Kari van den , Saga Anne Lise , Hager Helle Borgstrøm , Sandberg Sverre 
Published: May 2017

AbstractBackground:Errors in the preanalytical phase in clinical laboratories affect patient safety. The aim of this study was to evaluate the effect of intensive educational efforts together with external quality assessment (EQA) of the preanalytical phase from 2013 to 2015 to improve patient identification in primary health care in Norway. In addition, routines for venous and capillary blood sampling were investigated.Methods:A preanalytical EQA was circulated in 2013 by the Norwegian Quality Improvement of Laboratory Examinations (Noklus) to general practitioner offices and nursing homes (n=2000) to obtain information about important issues to focus on before launching an intensive educational program with courses, posters and visits in 2013–2015. Preanalytical EQA surveys were further circulated in 2014 and 2015.Results:The response rate varied between 42% and 55%. The percentages of participants asking for the patients’ name and the Norwegian identification number increased from about 8% in 2013 to about 35% in 2015. The increase was similar for those participating in only one EQA survey and for those who participated in EQA surveys both in 2013 and 2015. Guidelines for venous and capillary blood sampling were not always followed.Conclusions:Educational efforts more than the preanalytical EQA influenced the actions and resulted in an increase in the percentages of participants that followed the guidelines for patient identification. Some aspects of blood sampling routines need improvement.
The impact of pneumatic tube system on routine laboratory parameters: a systematic review and meta-analysis
Authors: Kapoula Georgia V. , Kontou Panagiota I. , Bagos Pantelis G. 
Published: May 2017

AbstractBackground:Pneumatic tube system (PTS) is a widely used method of transporting blood samples in hospitals. The aim of this study was to evaluate the effects of the PTS transport in certain routine laboratory parameters as it has been implicated with hemolysis.Methods:A systematic review and a meta-analysis were conducted. PubMed and Scopus databases were searched (up until November 2016) to identify prospective studies evaluating the impact of PTS transport in hematological, biochemical and coagulation measurements. The random-effects model was used in the meta-analysis utilizing the mean difference (MD). Heterogeneity was quantitatively assessed using the Cohran’sResults:From a total of 282 studies identified by the searching procedure, 24 were finally included in the meta-analysis. The meta-analysis yielded statistically significant results for potassium (K) [MD=0.04 mmol/L; 95% confidence interval (CI)=0.015–0.065; p=0.002], lactate dehydrogenase (LDH) (MD=10.343 U/L; 95% CI=6.132–14.554; p<10Conclusions:This meta-analysis suggests that PTS may be associated with alterations in K, LDH and AST measurements. Although these findings may not have any significant clinical effect on laboratory results, it is wise that each hospital validates their PTS.