bluuebunny/crossref_metadata_2025_split huggingface dataset:
Explaining the territorial trap: Revisiting the geographical assumptions of International Relations theory
Authors: Kadercan Burak 
Published: October 2024

Abstract
Territory and territoriality lie at the heart of both world politics and International Relations (IR) theory. In terms of IR theory’s geographical assumptions, one of the most influential studies to date has been political geographer John Agnew’s 1994 article on the ‘the territorial trap’ (TTT). While Agnew’s original insights and subsequent research has reached canonical status in political geography, mainstream IR scholarship has yet to fully engage TTT. Political geographers, in turn, have largely dealt with the consequences of TTT for our understanding of world politics. This study offers the first detailed account of the origins of TTT, which are hidden in broad daylight in IR’s own history. The origins of TTT and mainstream IR are intertwined in terms of two dynamics: the racist and colonial origins of IR, and the selective nationalistic ontology that dominated IR especially in the first half of the 20th century. The arguments offered in this study have a wide variety of implications for problematising the ways in which IR-as-epistemological-community approaches territory and territoriality as well as our understanding of the origins and evolution of the present-day global territorial order.
Trends in shigellosis notifications in England, January 2016 to March 2023
Authors: Charles Hannah , Sinka Katy , Simms Ian , Baker Kate S. , Godbole Gauri , Jenkins Claire 
Published: October 2024

Abstract
We reviewed all diagnoses of Shigella species notified to the UK Health Security Agency from January 2016 to March 2023. An overall increase in notifications of shigellosis was seen between 2016 (n = 415/quarter) and 2023 (n = 1 029/quarter). However, notifications dramatically declined between March 2020 and September 2021 during the COVID-19 pandemic (n = 208/quarter) highlighting the impact of travel and social distancing restrictions on transmission. S. sonnei diagnoses were more affected by lockdown restrictions than S. flexneri, most likely due to a combination of species-specific characteristics and host attributes. Azithromycin resistance continued to be associated with epidemics of sexually transmissible S. flexneri (adult males = 45.6% vs. adult females = 8.7%) and S. sonnei (adult males = 59.5% vs. adult females = 14.6%). We detected resistance to ciprofloxacin in S. sonnei from adult male cases not reporting travel at a higher frequency (79.4%) than in travel-associated cases (61.7%). Extensively drug-resistant Shigella species associated with sexual transmission among men almost exclusively had ESBL encoded by blaCTX-M-27, whereas those associated with returning travellers had blaCTX-M-15. Given the increasing incidence of infections and AMR, we recommend that enhanced surveillance is used to better understand the impact of travel and sexual transmission on the acquisition and spread of MDR and XDR Shigella species.
Epidemiology of scarlet fever in Victoria, Australia, 2007–2017
Authors: Phakey Sachin , Campbell Patricia T. , Gibney Katherine B. 
Published: October 2024

Abstract
In the last 10–15 years, there has been a global resurgence of scarlet fever, an infection historically associated with significant morbidity and mortality. It is unknown whether scarlet fever incidence has increased in Australia. We aimed to examine the incidence, predictors and severity of scarlet fever in the state of Victoria, Australia from 2007 to 2017, analyzing scarlet fever emergency department (ED) presentations, hospitalizations and deaths. Of the 1 578 scarlet fever cases during the study period, most occurred in children aged <10 years (1 344, 85%), in males (882, 56%), and during winter and spring months (918, 57%). There were no deaths with scarlet fever, however, 374 cases (24%) were admitted to hospital. The annual incidence of scarlet fever was stable during the study period (mean, 2.5; range, 1.9–3.1 cases per 100 000). Annual incidence was highest in children aged <5 years (19.3 per 100 000), and was 21% higher in males than females, adjusting for age and year (incidence rate ratio, 1.21, 95%CI 1.09–1.34). Whilst scarlet fever ED presentations and hospitalizations were stable in Victoria from 2007 to 2017, the recent identification of a Streptococcus pyogenes variant in Australia associated with epidemic scarlet fever overseas highlights the risk of future outbreaks.
The role of caregiver emotion regulation in youth mental health during the COVID-19 pandemic: A longitudinal study
Authors: Kim Stephanie Gyuri , Rodman Alexandra M. , Rosen Maya L. , Kasparek Steven W. , Mayes Makeda , Lengua Liliana J. , Meltzoff Andrew N. , McLaughlin Katie A. 
Published: October 2024

Abstract
The COVID-19 pandemic has presented youth and families with a broad spectrum of unique stressors. Given that adolescents are at increased risk for mental health and emotional difficulties, it is critical to explore family processes that confer resilience for youth in the face of stress. The current study investigated caregiver emotion regulation (ER) as a familial factor contributing to youth ER and risk for psychopathology following stressful life events. In a longitudinal sample of 224 youth (M
age
= 12.65 years) and their caregivers, we examined whether caregiver and youth engagement in ER strategies early in the pandemic mediated the associations of pandemic-related stress with youth internalizing and externalizing symptoms six months later. Leveraging serial mediation analysis, we demonstrated that caregiver and youth rumination, but not expressive suppression or cognitive reappraisal, mediated the prospective associations of pandemic-related stress with youth internalizing and externalizing symptoms. Greater exposure to pandemic-related stressors was associated with greater caregiver rumination, which, in turn, related to greater rumination in youth, and higher levels of youth internalizing and externalizing symptoms thereafter. Family interventions that target caregiver ER, specifically rumination, may buffer against the consequences of stress on youth engagement in maladaptive ER strategies and risk for psychopathology.
Attention-deficit hyperactivity disorder symptoms and bullying victimization from childhood to adolescence - A within-person cross-lagged approach
Authors: Stenseng Frode , Skalická Věra , Skaug Silje Stokke , Belsky Jay , Wichstrøm Lars 
Published: October 2024

Abstract
Attention-deficit hyperactivity disorder (ADHD) and subclinical symptoms of hyperactivity-impulsivity and inattentiveness coincide with an increased risk of peer victimization. What remains unclear are the developmental dynamics of these associations. In a sample drawn from two Norwegian birth cohorts (n = 872; 49.94 % girls), assessed biennially from age 6 to age 14, reciprocal relations between ADHD symptoms and victimization were examined while controlling for symptoms of anxiety and depression. ADHD symptoms were assessed through clinical interviews with parents, whereas victimization was reported by teachers using questionnaires. Random-intercept cross-lagged panel modeling revealed a consistent reciprocal within-person effect of increased ADHD symptoms on victimization, and vice versa. Analyses of subdimensions of ADHD projected a consistent cross-lagged bidirectional relationship between victimization and inattentiveness symptoms only, whereas no such reciprocity was found for hyperactivity-impulsivity symptoms. Results did not differ by gender. Findings suggest that the social context may constitute a vulnerability factor in the etiology of the inattentive subtype of ADHD, and at the same time, that inattentiveness symptoms pose a risk for becoming victimized.
Early warning signs for SPDEs with continuous spectrum
Authors: Bernuzzi Paolo , Düx Antonia Freya Susanne , Kuehn Christian 
Published: October 2024

Abstract
In this work, we study early warning signs for stochastic partial differential equations (SPDEs), where the linearisation around a steady state is characterised by continuous spectrum. The studied warning sign takes the form of qualitative changes in the variance as a deterministic bifurcation threshold is approached via parameter variation. Specifically, we focus on the scaling law of the variance near the transition. Since we are dealing here, in contrast to previous studies, with the case of continuous spectrum and quantitative scaling laws, it is natural to start with linearisations of the drift operator that are multiplication operators defined by analytic functions. For a one-dimensional spatial domain, we obtain precise rates of divergence. In the case of the two- and three-dimensional domains, an upper bound to the rate of the early warning sign is proven. These results are cross-validated by numerical simulations. Our theory can be generically useful for several applications, where stochastic and spatial aspects are important in combination with continuous spectrum bifurcations.
A familial case of aortic dilatation with p.Tyr470Cys in TGFBR2 in which the phenotype included only vascular lesions
Authors: Yamamoto Hidenori , Tanabe Ayako , Kato Taichi 
Published: October 2024

AbstractHereditary connective tissue diseases have different risks of aortic dissection depending on the causative gene. We report a family with no extravascular phenotype and a clinical diagnosis of familial thoracic aortic aneurysm and dissection, but genetic testing confirmed p.Tyr470Cys in TGFBR2, which is typically the responsible gene for Loeys–Dietz syndrome. Validation of the clinical diagnosis by genetic testing is warranted.
The Will of All in Kant’s Groundwork
Authors: Pendlebury T. A. 
Published: October 2024

AbstractIn Kant’s Groundwork II, the Formula of Universal Law (FUL) seems to be the argumentative link between the notion of a categorical imperative and later formulae (e.g. of humanity), its function as this link dependent on its equivalence to both. Some commentators have denied this equivalence and read the section as a failure. Others have abandoned its expository development by reading later formulae into the FUL. I argue that we need do neither if we distinguish the universality of the FUL from that of the will of all and read Groundwork II as extracting the latter from common moral cognition.
River of fire and ice: infrastructure, territoriality, and the colonization of eastern Hokkaido, Japan, 1600s–1900s
Authors: Watanabe Takehiro , Ito Takeshi 
Published: October 2024

AbstractFrom the seventeenth to the twentieth century, rivers played a key role in the colonization of Hokkaido, a northern island in the Japanese archipelago. The Kushiro River, in eastern Hokkaido, was transformed into infrastructure, a process which shaped the institutions, strategies, and practices of territorial control during the transition from the Tokugawa shogunate (1603–1868) to Imperial Japan (1868–1947). Trade between local Ainu communities and the shogunate's vassals contributed to a river-based territoriality. Later in the 1800s, as the island became territory of the modern state, the river was further converted into infrastructure through settler colonialism, industrial development, land reclamation, and the dispossession of indigenous communities. This transformation empowered the state to probe territories, exert control over labor, and access natural resources. Drawing on research on the political ecology of rivers, this paper focuses on two hydrosocial functions that emerged during the process of reworking river basins into legible and governable spaces: the transportation conduit and the water delivery system. The river's transition from a living system to infrastructure coincided with and furthered the establishment of colonial settlements and the expansion of the Japanese state's imperial reach.
Waves and Instabilities in Saturn's Magnetosheath: 2. Dispersion Relation Analysis
Authors: Cheng I. , Achilleos N. , Blanco‐Cano X. , Bertucci C. , Guio P. 
Published: October 2024

AbstractThe WHAMP (Rönnmark, 1982, https://inis.iaea.org/search/search.aspx?orig_q=RN:14744092) and LEOPARD (Astfalk & Jenko, 2017, https://doi.org/10.1002/2016ja023522) dispersion relation solvers were used to evaluate the growth rate and scale size for mirror mode (MM) and ion cyclotron (IC) instabilities under plasma conditions resembling Saturn's magnetosheath in order to compare observations to predictions from linear kinetic theory. Instabilities and waves are prevalent in planetary magnetosheaths. Understanding the origin and conditions under which different instabilities grow and dominate can help shed light on the role each instability plays in influencing the plasma dynamics of the region. For anisotropic plasmas modeled with bi‐Maxwellian particle distribution, the dispersion, growth rate, and scale size of MM and IC were studied as functions of proton temperature anisotropy, proton plasma beta, and oxygen ion abundance. The dispersion solvers showed that the IC mode dominated over MM under typical conditions in Saturn's magnetosheath, but that MM could dominate for high enough abundance . These water ion‐rich plasma conditions are occasionally found in Saturn's magnetosheath (Sergis et al., 2013, https://doi.org/10.1002/jgra.50164). The maximum linear growth rates for MM ranged from 0.02 to 0.2, larger than expected from observations. The scale size at maximum growth rate ranged from 4 to 12 , smaller than expected from observations. These inconsistencies could potentially be attributed to diffusion and non‐linear growth processes.
The Medium Energy Electron Telescope (MEET): Instrument Fabrication and Testing
Authors: Hogan Benjamin , Li Xinlin , O’Brien Declan , Cantilina Jared , Edgar William , Boyajian Spencer , Zhao Hong , Mei Yang 
Published: October 2024

AbstractThis manuscript is a follow up study to Hogan et al., (2024, https://doi.org/10.1029/2023JA032221) which describes the science motivation and development of the Medium Energy Electron Telescope (MEET). Medium Energy Electron Telescope is a 1U instrument optimized to measure 30–400 keV electrons in the inner radiation belt with fine energy resolution to resolve dynamics of these populations which are not well understood. Here we present the fabrication and testing of MEET to certify its performance in preparation for in‐space measurements. Assembly of an engineering model is shown. This unit has undergone vibration testing and these results are discussed. The electronics of the instrument are tested after these environmental tests including electron measurements with pulse injection and a radioactive source. Test results indicate the instrument is viable for flight on a potential mission by satisfying noise requirements and reproduction of an input flux spectrum. The noise of expected input signals is quantified to be <∼6 keV allowing for <20% dE/E for 30 keV electrons. Strontium‐90 radioactive source tests were conducted. Using measured count rates from MEET's electron energy channels, we reproduce the strontium‐90 spectrum proving the instrument's ability to measure flux of 30–800 keV electrons with fine nominal energy resolution (<20% dE/E for <60 keV, and <10% for >60 keV electrons). These results demonstrate MEET's performance in a relevant environment via ground testing. Medium Energy Electron Telescope is available for future missions to provide novel electron measurements in the inner radiation belt.
Sustained greening of the Antarctic Peninsula observed from satellites
Authors: Roland Thomas P. , Bartlett Oliver T. , Charman Dan J. , Anderson Karen , Hodgson Dominic A. , Amesbury Matthew J. , Maclean Ilya , Fretwell Peter T. , Fleming Andrew 
Published: October 2024

AbstractThe Antarctic Peninsula has experienced considerable anthropogenic warming in recent decades. While cryospheric responses are well defined, the responses of moss-dominated terrestrial ecosystems have not been quantified. Analysis of Landsat archives (1986–2021) using a Google Earth Engine cloud-processing workflow suggest widespread greening across the Antarctic Peninsula. The area of likely vegetation cover increased from 0.863 km2 in 1986 to 11.947 km2 in 2021, with an accelerated rate of change in recent years (2016–2021: 0.424 km2 yr−1) relative to the study period (1986–2021: 0.317 km2 yr−1). This trend echoes a wider pattern of greening in cold-climate ecosystems in response to recent warming, suggesting future widespread changes in the Antarctic Peninsula’s terrestrial ecosystems and their long-term functioning.
Comparative proteomic analysis of regenerative mechanisms in mouse retina to identify markers for neuro-regeneration in glaucoma
Authors: Wang Xiaosha , Frühn Layla , Li Panpan , Shi Xin , Wang Nini , Feng Yuan , Prinz Julia , Liu Hanhan , Prokosch Verena 
Published: October 2024

AbstractThe retina is part of the central nervous system (CNS). Neurons in the CNS and retinal ganglion cells lack the ability to regenerate axons spontaneously after injury. The intrinsic axonal growth regulators, their interaction and roles that enable or inhibit axon growth are still largely unknown. This study endeavored to characterize the molecular characteristics under neurodegenerative and regenerative conditions. Data-Independent Acquisition Mass Spectrometry was used to map the comprehensive proteome of the regenerative retina from 14-day-old mice (Reg-P14) and adult mice after lens injury (Reg-LI) both showing regrowing axons in vitro, untreated adult mice, and retina from adult mice subjected to two weeks of elevated intraocular pressure showing degeneration. A total of 5750 proteins were identified (false discovery rate < 1%). Proteins identified in both Reg-P14 and Reg-LI groups were correlated to thyroid hormone, Notch, Wnt, and VEGF signaling pathways. Common interactors comprising E1A binding protein P300 (EP300), CREB binding protein (CBP), calcium/calmodulin dependent protein kinase II alpha (CaMKIIα) and sirtuin 1 (SIRT1) were found in both Reg-P14 and Reg-LI retinas. Proteins identified in both regenerating and degenerative groups were correlated to thyroid hormone, Notch, mRNA surveillance and measles signaling pathways, along with PD-L1 expression and the PD-1 checkpoint pathway. Common interactors across regenerative and degenerative retinas comprising NF-kappa-B p65 subunit (RELA), RNA-binding protein with serine-rich domain 1 (RNPS1), EP300 and SIN3 transcription regulator family member A (SIN3A). The findings from our study provide the first mapping of regenerative mechanisms across postnatal, mature and degenerative mouse retinas, revealing potential biomarkers that could facilitate neuro-regeneration in glaucoma.
Pharmacokinetics of pulmonary indacaterol in rat lung using molecular imprinting solid-phase extraction coupled with RP-UPLC
Authors: Tarek Mohamed , Ghoniem Nermine S. , Hegazy Maha A. , Wagdy Hebatallah A. 
Published: October 2024

AbstractIndacaterol, a β2 agonist prescribed for long-term management of patients with chronic obstructive pulmonary disease and asthma. In this study the first MISPE cartridges was developed using indacaterol as a template for its selective extraction from rat lung tissues, enabling precise pharmacokinetic evaluation at the drug’s site of action. A molecular imprinting polymer was synthesized using indacaterol as a template, methacrylic acid as a functional monomer and ethylene glycol dimethacrylate as a cross-linker with a molar ratio (1: 4: 20). The polymer was characterized by a high binding capacity of 9840 ± 0.86 and high selectivity with an imprinting factor of 4.53 ± 0.12. The synthesized polymer was utilized as a sorbent in solid-phase extraction to purify and extract indacaterol from lung tissue matrix. The optimum molecularly imprinted solid-phase extraction (MISPE) conditions were 20.0 mg of molecular imprinting polymer and non-imprinting polymer, acetonitrile as the loading solvent, acetonitrile: water (20: 80; by volume) as the washing solvent, and methanol: acetic acid (90: 10; by volume) as the eluting solvent. A pharmacokinetic study was performed for indacaterol in rat lungs using the synthesized and optimized MISPE cartridge as a tool for sample purification. These parameters were determined in the lung tissues of rats emphasizing the local exposure of indacaterol to its target organ. The Cmax and Tmax were 51.020 ± 2.810 µg mL− 1 and 0.083 ± 0.001 h, respectively. The AUC 0−24 and AUC0 − inf were 175.920 ± 1.053 and 542.000 ± 5.245 µg h mL− 1, respectively. The elimination rate constant was 0.014 ± 0.00012 h− 1 and the half-life time was 48.510 ± 0.012 h. This study successfully developed and optimized MISPE cartridges using indacaterol as a template, enabling precise pharmacokinetic evaluation in rat lung tissues. The cartridges demonstrated high binding capacity and selectivity, providing crucial insights into the local exposure of indacaterol at its site of action.
Recalibrated FRIEND equation for peak oxygen pulse is accurate in endurance athletes: the NOODLE study
Authors: Kasiak Przemysław , Kowalski Tomasz , Klusiewicz Andrzej , Zdanowicz Ryszard , Ładyga Maria , Wiecha Szczepan , Mamcarz Artur , Śliż Daniel 
Published: October 2024

AbstractPeak oxygen pulse (O2Ppeak) is an important index of cardiorespiratory fitness (CRF). The FRIEND database is a global source of reference values for CRF. However, no reference equation is tailored for endurance athletes (EA) to predict O2Ppeak. Here, we adjusted the well-established FRIEND equation for O2Ppeak to the characteristics of the EA population. 32 (34.0%) female EA and 62 (66.0%) male well-trained EA underwent maximal cardiopulmonary exercise test on a treadmill. V̇O2max was 4.5 ± 0.5 L min−1 in males and 3.1 ± 0.4 L min−1 in females. O2Ppeak was 23.6 ± 2.8 mL beat−1 and 16.4 ± 2.0 mL beat−1 for males and females, respectively. Firstly, we externally validated the original FRIEND equation. Secondly, using multiple linear regression, we adjusted the FRIEND equation for O2Ppeak to the population of EA. The original FRIEND equation underestimated O2Ppeak for 2.9 ± 2.9 mL beat−1 (P < .001) in males and 2.2 ± 2.1 mL beat−1 (P < .001) in females. The updated equation was 1.36 + 1.07 (23.2 · 0.09 · age − 6.6 [if female]). The new equation explained 62% of the variance and significantly predicted O2Ppeak (R2 = 0.62, β = 0.78, P < .001). The error of the EA-adjusted model was 0.1 ± 2.9 mL beat−1 (P = .82) and 0.2 ± 2.1 mL beat−1 (P = .65) for males and females respectively. Recalibration of the original FRIEND equation significantly enhances its accuracy among EA. The error of the EA-adjusted model was negligible. A new recalibrated equation should be used to predict O2Ppeak in the population of EA.