bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dental fear among transgender individuals ‐ a cross‐sectional survey
Authors: Heima Masahiro , Heaton Lisa J. , Ng Henry H. , Roccoforte Elisabeth C. 
Published: October 2017

ABSTRACTAimsThe aims of this study were to: (1) evaluate the level of dental fear among transgender individuals and (2) investigate specific predictors of dental fear in individuals who identify as transgender.Method and resultsAn anonymous survey among transgender adults was conducted using both a web‐based and paper survey. The survey included the Dental Fear Survey (DFS), history of hormonal interventions, perceived gender roles, and demographic information. The bivariate analyses did not show a significant difference in DFS between sex assigned at birth (p = 0.628) or among gender identities (p = 0.109). A regression model analysis for the level of DFS by using participants’ demographic information as independent variables indicated the fear and experience of discrimination/maltreatment were significant predictors of dental fear; standardized beta coefficients (p‐value) were 0.35 (p = 0.017) and 0.28 (p = 0.041), respectively.ConclusionThe fear and experiences of discrimination/maltreatment were significantly positively associated with their level of dental fear.
Aligning Funding and Need for Family Planning: A Diagnostic Methodology
Authors: Fan Victoria Y. , Kim Sunja , Choi Seemoon , Grépin Karen A. 
Published: October 2017

AbstractWith limited international resources for family planning, donors must decide how to allocate their funds to different countries. How can a donor for family planning decide whether countries are adequately prioritized for funding? This article proposes an ordinal ranking framework to identify under‐prioritized countries by rank‐ordering countries by their need for family planning and separately rank‐ordering them by their development assistance for family planning. Countries for which the rank of the need for family planning is lower than the rank of its funding are deemed under‐prioritized. We implement this diagnostic methodology to identify under‐prioritized countries that have a higher need but lower development assistance for family planning. This approach indicates whether a country is receiving less compared to other countries with similar levels of need.
Mainstreaming ‘Women’ without feminisms in psychology
Authors: Thompson Lucy 
Published: October 2017

AbstractAlthough it has been argued that feminist work has gained recognition in mainstream psychology (Eagly, Eaton, Rose, Riger, & McHugh, ), these arguments tend to cite a proliferation of research in high‐ranking Euro‐American academic journals, on topics that concern women or gender in psychology. However, the majority of this work is not presented as explicitly feminist. Rather, it tends to be incorporated into mainstream spaces under the umbrella of the psychology of women. This is often interpreted uncritically to mean the study of womanhood as a stable category or variable, reproducing binary accounts of sex and gender that are largely devoid of feminist analysis. Not only do these interpretations reify essentialist constructions of womanhood; they also convert transformative feminist politics into singular and special interest ‘women's issues’. Indeed, broad feminist theoretical perspectives remain largely absent at the fundamental levels of mainstream psychological knowledge production (Eagly et al., ; Eagly & Riger, ). Thus, while credit has been given to the growing visibility of issues concerning women and gender in the discipline, less critical attention has been paid to the broader absence of feminist language in this work. As such, instances of mainstream inclusion have come to take priority over broader issues of feminist exclusions in psychology. Taking a critical position on the discipline from within the context of the Global North, this paper questions the state of mainstream inclusions and reasserts the transformative potentials of diverse feminisms (Liebert, Leve, & Hui, ), arguing that current inclusions of women without feminisms in psychology are problematic. Drawing on recent mobilisations of the psychology of women in the interests of ‘male psychology’, it is argued that the transformative potentials of feminist psychologies are more likely to be stifled than supported by mainstream inclusions.
“Treading in sand”: A qualitative study of the impact of austerity on inequalities in mental health
Authors: Mattheys Kate , Warren Jonathan , Bambra Clare 
Published: October 2017

AbstractSuccessive UK governments since 2010 have adopted policies of austerity characterized by public spending and social security cuts. There has been little qualitative research exploring the effects of these policies on inequalities in mental health. This article presents findings from a case study of Stockton‐on‐Tees, a local authority in the North East of England with exceptionally high spatial and socio‐economic inequalities. Qualitative interviews were undertaken with people experiencing mental health problems in different areas of the local authority, alongside interviews with key stakeholders. The findings offer an insight into spatial inequalities in people's lives, and the impact of deprivation on mental health. They suggest that austerity measures are having a damaging impact on individuals and communities in the most deprived areas of this unequal place, whilst leaving those from less deprived areas relatively unscathed—with the exception of increased job insecurity. The cuts in social security are impacting on health through both material and psychosocial pathways including increased financial hardship and chronic stress. The intrusion of the state into people's everyday lives was such that the notion of the “home as an asylum” was broken, giving many no respite from the draining day‐to‐day experiences of poverty. The findings are discussed in relation to the continuing program of welfare changes and public spending cuts in the United Kingdom, including avenues for further research and key recommendations for policymakers.
Accounting for uncertainties in ammonia emission from manure applied to grassland
Authors: Goedhart P. W. , Huijsmans J. F. M. 
Published: October 2017

AbstractA recent study has raised doubts about the ammonia emission reduction achieved in the Netherlands when applying manure to grassland by means of low‐emission techniques such as narrow band and shallow injection. The critics claim that percentages of ammonia released to the atmosphere associated with low‐emission techniques might even overlap with that from surface broadcast spreading given the large alleged experimental uncertainties in measurements. Consequently, the rationale behind the regulations to which farmers are exposed is questioned. In this study, it is shown that the alleged large uncertainties were obtained by means of an erroneous statistical method and that the real uncertainties are much smaller. It is also shown that, even when there is a large uncertainty in individual measurements, previous conclusions about differences in emission between different manure application techniques are still valid. It is further argued in this study that uncertainty in the percentage of applied ammonia emitted is implicitly taken into account in any comparative statistical analysis conducted in the past.
A uniform method for the simultaneous blood group phenotyping of Fya, Fyb, Jka, Jkb, S, s̅, P1, k applying lateral‐flow technique
Authors: Caesar A. , Meyer S. , Trost N. , Neuenschwander K. , Geisen C. , Frey B. M. , Gassner C. , Schwind P. 
Published: October 2017

Background and ObjectivesA lateral flow assay for simultaneous blood group typing of ABO, RhD, C, E, c, e, Cw and K with stable end‐point and without centrifugation is in routine use since several years (MDmulticard®).The typing of extended phenotype parameters belonging to the Duffy, Kidd, MNSs blood group systems and others, however, has not yet been demonstrated for this technique.Reliable detection of Fyx, a weak Fyb phenotype with a pronounced quantitative reduction of the number of Fyb antigens on the erythrocyte surface, remains a weakness of current serological blood grouping techniques.Material and MethodsThe performance characteristics of the following reagents were evaluated in donor and patient samples in lateral flow technology (MDmulticard®): Anti‐Fya, ‐Fyb, ‐Jka, ‐Jkb, ‐S, ‐s̅, ‐P1 and ‐k. The sensitivity to detect Fyx was in addition evaluated with Fyx positive samples, which had been preselected by MALDI‐TOF MS‐based genotyping.ResultsAll results obtained with the MDmulticard® were in full accordance with those of the CE‐certified reference products for all the eight reagent formulations used: Anti‐Fya, ‐Fyb, ‐Jka, ‐Jkb, ‐S, ‐s̅, ‐P1 and –k. Also, all Fyx phenotypes of the selected population of 93 positive samples, originally identified by MALDI‐TOF MS‐based genotyping, were reliably detected by the lateral flow assay.ConclusionExtended phenotype blood group parameters, including the serologically challenging Fyx phenotype, can be determined simultaneously, rapidly and accurately using the lateral flow (MDmulticard®) technology, even in cases when IgG class antibodies are the only source of diagnostic antibodies.
Use of computed tomography and minimum intensity projection in the detection of lobar pneumonia mimicking lung lobe torsion in a dog
Authors: Lee Sang‐Kwon , Cho Kyoung‐Oh , Alfajaro Mia Madel , Lee Juhwan , Yu Dohyeon , Choi Jihye 
Published: October 2017

AbstractA 10‐year‐old female spayed Dachshund was referred with progressive coughing for 1 month. The dog was tentatively diagnosed with right middle lung torsion based on pleural effusion, vesicular emphysema, abruptly ending bronchus in consolidated right middle lung, and no contrast enhancement of the affected lobe on radiography and computed tomography (CT). There was no evidence of torsion upon thoracotomy, and histological examination confirmed lobar pneumonia. The CT images were reevaluated using minimum intensity projection and revealed normal bronchial courses. The minimum intensity projection technique can be to assist in evaluation of the bronchial tree for dogs with suspected lung lobe torsion and other pulmonary diseases.
Dilution Factor of Quantitative Bacterial Cultures Obtained by Bronchoalveolar Lavage in Patients with Ventilator-Associated Bacterial Pneumonia
Authors: Drusano George L. , Corrado Michael L. , Girardi Gino , Ellis-Grosse Evelyn J. , Wunderink Richard G. , Donnelly Helen , Leeper Kenneth V. , Brown Mona , Malek Tasnova , Hite Robert Duncan , Ferrari Michelle , Djureinovic Danijela , Kollef Marin H. , Mayfield Lisa , Doyle Ann , Chastre Jean , Combes Alain , Walsh Thomas J. , Dorizas Krisztina , Alnuaimat Hassan , Morgan Brooks Edward , Rello Jordi , Torre Cristopher Alan Mazo , Jones Ronald N. , Flamm Robert K. , Woosley Leah , Ambrose Paul G. , Bhavnani Sujata , Rubino Christopher M. , Bulik Catharine C. , Louie Arnold , Vicchiarelli Michael , Berman Colleen 
Published: October 2017

ABSTRACT

Ventilator-associated bacterial pneumonia (VABP) is a difficult therapeutic problem. Considerable controversy exists regarding the optimal chemotherapy for this entity. The recent guidelines of the Infectious Diseases Society of America and the American Thoracic Society recommend a 7-day therapeutic course for VABP based on the balance of no negative impact on all-cause mortality, less resistance emergence, and fewer antibiotic treatment days, counterbalanced with a higher relapse rate for patients whose pathogen is a nonfermenter. The bacterial burden causing an infection has a substantial impact on treatment outcome and resistance selection. We describe the baseline bronchoalveolar lavage (BAL) fluid burden of organisms in suspected VABP patients screened for inclusion in a clinical trial. We measured the urea concentrations in plasma and BAL fluid to provide an index of the dilution of the bacterial and drug concentrations in the lung epithelial lining fluid introduced by the BAL procedure. We were then able to calculate the true bacterial burden as the diluted colony count times the dilution factor. The median dilution factor was 28.7, with the interquartile range (IQR) being 11.9 to 53.2. Median dilution factor-corrected colony counts were 6.18 log
10
(CFU/ml) [IQR, 5.43 to 6.46 log
10
(CFU/ml)]. In a subset of patients, repeat BAL on day 5 showed a good stability of the dilution factor. We previously showed that large bacterial burdens reduce or stop bacterial killing by granulocytes. (This study has been registered at ClinicalTrials.gov under registration no. NCT01570192.)
In Vitro
Combination of Isavuconazole with Echinocandins against Azole-Susceptible and -Resistant Aspergillus spp
Authors: Raffetin A. , Courbin V. , Jullien V. , Dannaoui E. 
Published: October 2017

ABSTRACT

In vitro
combinations of isavuconazole with echinocandins were evaluated against 30
Aspergillus
strains with a two-dimensional checkerboard microdilution method and an agar-based diffusion method. With the checkerboard method, the three combinations showed indifferent interactions for all strains. With the agar-based method, indifferent interactions were found for all strains for isavuconazole-micafungin and isavuconazole-anidulafungin. For the isavuconazole-caspofungin combination, indifference was found in 24/30 strains, synergism in 4/30 strains, and antagonism in 2/30 strains.
Activity of Meropenem-Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in a Murine Model of Pyelonephritis
Authors: Weiss William J. , Pulse Mark E. , Nguyen Phung , Peterson Kelly , Silva Jessica , Simecka Jerry W. , Valtierra David , Sabet Mojgan , Griffith David C. 
Published: October 2017

ABSTRACT

The recently approved combination of meropenem and vaborbactam (Vabomere) is highly active against Gram-negative pathogens, especially
Klebsiella pneumoniae
carbapenemase (KPC)-producing, carbapenem-resistant
Enterobacteriaceae
. We evaluated the efficacy of meropenem-vaborbactam against three clinically relevant isolates in a murine pyelonephritis model. The data indicate that the combination of meropenem and vaborbactam significantly increased bacterial killing compared to that with the untreated controls. These data suggest that this combination may have utility in the treatment of complicated urinary tract infections due to KPC-producing, carbapenem-resistant
Enterobacteriaceae
.
Putative Integrative Mobile Elements That Exploit the Xer Recombination Machinery Carrying
bla
IMI
-Type Carbapenemase Genes in Enterobacter cloacae Complex Isolates in Singapore
Authors: Koh Tse H. , Rahman Nurdyana Binte Abdul , Teo Jeanette W. P. , La My-Van , Periaswamy Balamurugan , Chen Swaine L. 
Published: October 2017

ABSTRACT

Whole-genome sequencing was performed on 16 isolates of the carbapenemase-producing
Enterobacter cloacae
complex to determine the flanking regions of
bla
IMI
-type genes. Phylogenetic analysis of multilocus sequence typing (MLST) targets separated the isolates into 4 clusters. The
bla
IMI
-type genes were all found on Xer-dependent integrative mobile elements (IMEX). The IMEX elements of 5 isolates were similar to those described in Canada, while the remainder were novel. Five isolates had IMEX elements lacking a resolvase and recombinase.
Emotional reactions in parents of the youth who experienced the Utøya shooting on 22 July 2011; results from a cohort study
Authors: Holt Tonje , Jensen Tine , Dyb Grete , Wentzel-Larsen Tore 
Published: October 2017

Objective and settingThe objective of this study was to provide knowledge about the emotional reactions in parents whose offspring experienced a mass shooting on Utøya island in Norway in 2011. The research questions included whether parents’ reactions were influenced by their offspring’s symptom level, age, living situation and parental gender.DesignThe study was designed as an open cohort study. The data were collected at two time points; 4–5 months and 14–15 months after the shooting.ParticipantsThe participants were 531 parents of youth exposed to the Utøya island attack.Outcome measuresThe Parental Emotional Reaction Questionnaire measured parents’ reactions, and University of California, Los Angeles Post-traumatic Stress Disorder Reaction Index measured youths' post-traumatic stress symptoms.ResultsParental emotional reactions were positively related to post-traumatic stress reactions in offspring at wave 1: Est.=0.20, 95% CI 0.10 to 0.30, p<0.001, over time (wave 1and wave 2 nested within individuals): Est.=0.23, CI 0.13 to 0.32, p<0.001, and at wave 2: Est.=0.26, CI 0.12 to 0.39, p<0.001. Youths’ age was not significantly related to parental emotional reactions, neither at wave 1: Est.=0.19, CI −0.40 to 0.77, p=0.531, over time: Est.=0.26, CI −0.27 to 0.79, p=328, nor at wave 2: Est.=0.32, CI −0.41 to 1.05, p=0.389. Mothers were more emotionally upset than fathers both at wave 1: Est.=−5.66, CI −7.63 to −3.69, p<0.001, over time: Est.=−5.36, CI −7.18 to −3.55, p<0.001, and at wave 2: Est.=−5.33, CI −7.72 to −2.53, p<0.001.ConclusionsThe findings suggest that parenting after trauma should be addressed in outreach programmes and in planning of healthcare services.
Change in non-alcoholic beverage sales following a 10-pence levy on sugar-sweetened beverages within a national chain of restaurants in the UK: interrupted time series analysis of a natural experiment
Authors: Cornelsen Laura , Mytton Oliver T , Adams Jean , Gasparrini Antonio , Iskander Dalia , Knai Cecile , Petticrew Mark , Scott Courtney , Smith Richard , Thompson Claire , White Martin , Cummins Steven 
Published: October 2017

BackgroundThis study evaluates changes in sales of non-alcoholic beverages in Jamie’s Italian, a national chain of commercial restaurants in the UK, following the introduction of a £0.10 per-beverage levy on sugar-sweetened beverages (SSBs) and supporting activity including beverage menu redesign, new products and establishment of a children’s health fund from levy proceeds.MethodsWe used an interrupted time series design to quantify changes in sales of non-alcoholic beverages 12 weeks and 6 months after implementation of the levy, using itemised electronic point of sale data. Main outcomes were number of SSBs and other non-alcoholic beverages sold per customer. Linear regression and multilevel random effects models, adjusting for seasonality and clustering, were used to investigate changes in SSB sales across all restaurants (n=37) and by tertiles of baseline restaurant SSB sales per customer.ResultsCompared with the prelevy period, the number of SSBs sold per customer declined by 11.0% (−17.3% to −4.3%) at 12 weeks and 9.3% (−15.2% to −3.2%) at 6 months. For non-levied beverages, sales per customer of children’s fruit juice declined by 34.7% (−55.3% to −4.3%) at 12 weeks and 9.9% (−16.8% to −2.4%) at 6 months. At 6 months, sales per customer of fruit juice increased by 21.8% (14.0% to 30.2%) but sales of diet cola (−7.3%; −11.7% to −2.8%) and bottled waters (−6.5%; −11.0% to −1.7%) declined. Changes in sales were only observed in restaurants in the medium and high tertiles of baseline SSB sales per customer.ConclusionsIntroduction of a £0.10 levy on SSBs alongside complementary activities is associated with declines in SSB sales per customer in the short and medium term, particularly in restaurants with higher baseline sales of SSBs.
DFT study on thermo-elastic properties of Ru2FeZ (Z = Si, Ge, Sn) Heusler alloys
Authors: Iftikhar Aneeza , Ahmad Afaq , Ahmad Iftikhar , Rizwan Muhammad 
Published: October 2017

We studied the thermo-elastic properties of Ru2FeZ (Z[Formula: see text]=[Formula: see text]Si, Ge, Sn) Heusler alloys within the framework of density functional theory. Thermo-elastic properties corresponding to elastic modulus, anisotropy, phase stability, elastic wave velocities, thermal stability, Debye temperature, melting temperature, thermal conductivity and formation energy are calculated. The elastic constants C[Formula: see text] predict the structural and dynamical stabilities while the formation energies show thermal stability of the alloys at 0 K. Pugh’s and Poisson’s ratios display the ductile nature of alloys. All alloys are anisotropic and we also observed that Ru2FeSn is the hardest material than Ru2FeSi and Ru2FeGe. Moreover, longitudinal mode of vibrations are also observed and are maximum along [100], [110] and [111] directions than the transverse mode of vibrations.
Tumor PDCD1LG2 (PD-L2) Expression and the Lymphocytic Reaction to Colorectal Cancer
Authors: Masugi Yohei , Nishihara Reiko , Hamada Tsuyoshi , Song Mingyang , da Silva Annacarolina , Kosumi Keisuke , Gu Mancang , Shi Yan , Li Wanwan , Liu Li , Nevo Daniel , Inamura Kentaro , Cao Yin , Liao Xiaoyun , Nosho Katsuhiko , Chan Andrew T. , Giannakis Marios , Bass Adam J. , Hodi F. Stephen , Freeman Gordon J. , Rodig Scott J. , Fuchs Charles S. , Qian Zhi Rong , Nowak Jonathan A. , Ogino Shuji 
Published: October 2017

Abstract
Expression of the immune checkpoint ligand CD274 (programmed cell death 1 ligand 1, PD-L1, from gene CD274) contributes to suppression of antitumor T cell–mediated immune response in various tumor types. However, the role of PDCD1LG2 (PD-L2, CD273, from gene PDCD1LG2) in the tumor microenvironment remains unclear. We hypothesized that tumor PDCD1LG2 expression might be inversely associated with lymphocytic reactions to colorectal cancer. We examined tumor PDCD1LG2 expression by IHC in 823 colon and rectal carcinoma cases within two U.S.-nationwide cohort studies and categorized tumors into quartiles according to the percentage of PDCD1LG2–expressing carcinoma cells. We conducted multivariable ordinal logistic regression analysis to assess the associations of tumor PDCD1LG2 expression with Crohn-like lymphoid reaction, peritumoral lymphocytic reaction, intratumoral periglandular reaction, or tumor-infiltrating lymphocytes, controlling for potential confounders, including microsatellite instability, CpG island methylator phenotype, long-interspersed nucleotide element-1 methylation, and KRAS, BRAF, and PIK3CA mutations. Tumor PDCD1LG2 expression was inversely associated with Crohn-like lymphoid reaction (Ptrend = 0.0003). For a unit increase in the three-tiered ordinal categories of Crohn-like lymphoid reaction, a multivariable OR in the highest (vs. lowest) quartile of the percentage of PDCD1LG2–expressing tumor cells was 0.38 (95% confidence interval, 0.22–0.67). Tumor PDCD1LG2 expression was not associated with peritumoral lymphocytic reaction, intratumoral periglandular reaction, tumor-infiltrating lymphocytes, or patient survival (Ptrend &gt; 0.13). Thus, tumor PDCD1LG2 expression is inversely associated with Crohn-like lymphoid reaction to colorectal cancer, suggesting a possible role of PDCD1LG2-expressing tumor cells in inhibiting the development of tertiary lymphoid tissues during colorectal carcinogenesis. Cancer Immunol Res; 5(11); 1046–55. ©2017 AACR.