bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of poor health-related quality of life among outpatients with rheumatoid arthritis in Jordan
Authors: Jarab Anan S. , Al-Qerem Walid , Abu Heshmeh Shrouq R. , Alzoubi Karem H. , Al Hamarneh Yazid N. , Akour Amal 
Published: October 2024

Objective
The purpose of this study was to assess the health-related quality of life (HRQOL) and investigate the variables contributing to reduced HRQOL in patients with rheumatoid arthritis.

Methods
The present cross-sectional study was conducted on patients diagnosed with rheumatoid arthritis at two teaching hospitals in Jordan using a convenience sampling technique. The participants were interviewed face-to-face during the scheduled appointment at the outpatient rheumatology clinic. The HRQOL was evaluated by the validated EuroQol-5 Dimension (EQ-5D) questionnaire, which included the EQ-5D utility index that evaluated HRQOL in terms of 5 domains, including mobility, self-care, usual activities, pain/discomfort, and anxiety/depression, and the EQ-5D visual analogue scale (EQ-5DVAS), which evaluated HRQOL on a vertical scale ranging from 0 (worst imaginable health) to 100 (best imaginable health). The validated short version of the 19-item Compliance Questionnaire for Rheumatology (CQR-5) was used to evaluate medication adherence. The Clinical Disease Activity Index (CDAI) was used to assess disease activity among the study participants. A stepwise quantile regression model (q = 0.5) was conducted to explore the factors associated with the EQ-5DUtility Index and EQ-5DVAS scores.

Results
In total, 261 patients with RA participated in the study. The median (interquartile range) of the EQ-5DUtility Index and EQ-VAS scores was 0.552 (0.006–0.726) and 0.506 (0.233–0.690), respectively. Regression analysis results demonstrated that medication non-adherence (regression coefficient (β) = -0.348, P<0.01), not performing regular physical activity (β = -0.209, P<0.01), and higher disease activity as measured by the CDAI score (β = -0.015, P<0.01) were significant predictors of a lower EQ-5DUtility Index score. In addition, medication non-adherence (β = -0.199, P<0.01), not performing regular physical activity (β = -0.117, P<0.01), increased body mass index (BMI) (β = -0.009, P<0.01), and higher CDAI score (β = -0.009, P<0.01) were significant predictors of low EQ-5DVAS score.

Conclusions
Patients with RA experienced significantly impaired HRQOL. Medication non-adherence, not performing regular physical activity, increased body weight, and increased disease activity were identified as determinants of poor HRQOL among patients with RA in the present study. Treating physicians should encourage regular physical activity, maintaining a healthy body weight, and controlling disease activity to improve HRQOL in patients with RA.
Hamiltonian isotopies of relatively exact Lagrangians are orientation-preserving
Authors: Smith Jack 
Published: October 2024

Abstract
Given a closed, orientable Lagrangian submanifold L in a symplectic manifold (X, ω), we show that if L is relatively exact then any Hamiltonian diffeomorphism preserving L setwise must preserve its orientation. In contrast to previous results in this direction, there are no spin hypotheses on L. Curiously, the proof uses only mod 2 coefficients in its singular and Floer cohomology rings.
Deformations of pairs of codimension one foliations
Authors: Ndiaye Ameth , Wade Aïssa 
Published: October 2024

Abstract
The notion of a linear deformation of a codimension one foliation into contact structures was introduced in [5]. This concept is a special type of deformation of confoliations. In this paper, we study linear deformations of pairs of codimension one foliations into contact pairs. Applications of our main result are also provided.
Thermal modification of Lantana camara stalks and its characterization
Authors: Dan Sanmitra , Kumar Shailendra , Nagarajappa Giridhar B. , Pandey Krishna K. 
Published: October 2024

Abstract
This paper deals with value addition and utilization of Lantana camara, an invasive species with unprecedented rate of growth, by thermal modification. Lantana
camara stalks were thermally modified using vacuum heat treatment (VHT), oil heat treatment (OHT), and steam heat treatment (SHT) at 180 °C and 200 °C and subsequently changes in physical, chemical and mechanical properties were studied. Weight loss was observed in vacuum and steam heat treated samples due to thermal degradation while oil heat treated samples showed weight gain due to oil uptake. SHT exhibited the highest (19 %) weight loss at 200 °C. The color of the modified lantana attained uniform dark colour, OHT exhibited the most intense effect on colour changes. Fourier transform infrared (FTIR) and Fourier transform near infrared (FTNIR) spectroscopic analyses indicated degradation of hemicellulose and change in cellulose crystallinity due to heat treatment. Dimensional stability of thermally modified Lantana stalks improved across treatments, with SHT achieving the highest anti-swelling efficiency of 67.3 % at 200 °C and lowest water absorption (43 %) after 72 h of water soaking. The dynamic modulus of elasticity of thermally modified Lantana remained constant in all the treatment processes. Overall, the results indicate that thermal modification can increase utilization potential of L. camara.
A formal approach to reanalysis and the Early Semantic Stability Hypothesis: exploring the test case of the negative counterfactual marker ʾilmale in Hebrew and Aramaic
Authors: Bar-Asher Siegal Elitzur A. 
Published: October 2024

Abstract
This study delves into the intricate process of reanalysis, wherein linguistic expressions undergo grammatical or semantic changes, or sometimes both. The primary objective of this study is to explore the theoretical aspects surrounding historical changes of this nature. To facilitate a comprehensive understanding of the topic, we provide a formal description of reanalysis as an analytical tool. Our formal description allows for the differentiation of various change scenarios, enabling us to identify distinct types of shifts from one analysis to another. This approach not only focuses on what has been reanalyzed, be it the morphology, syntax, or the semantics, but also emphasizes the interplay between all three linguistic modules (Form, Grammar, and Meaning) and their relationships. This holistic perspective enables a systematic examination of the significance of what remains constant at both points in time during the reanalysis process. The key insight arising from this analysis leads us to propose and substantiate the Early Semantic Stability Hypothesis. This hypothesis posits that the truth-conditional semantics of the original proposition remain unchanged throughout reanalysis, either in all contexts or in specific “bridging contexts” where the reanalysis occurs. To demonstrate these phenomena, we present a compelling test case, focusing on the development of the counterfactual conditional marker ʾilmale in Hebrew and Aramaic. Through a detailed examination of the syntactic and semantic reanalyses it underwent, we observe the emergence of unique semantic features. By adopting a formal semantic perspective, we address fundamental questions such as the level of ambiguity required for reanalysis to take place, the potential existence of universal constraints on reanalysis, and potential motivations driving these linguistic changes. This investigation provides valuable insights into the intricate mechanisms at play during reanalysis and contributes to the broader understanding of linguistic evolution and development.
Sub-picosecond biphasic ultrafast all-optical switching in ultraviolet band
Authors: Dong Xiaoxiang , He Yonglin , Zhu Tao , Gao Renxian , Hu Lingyun , Li Jiayu , Ren Peiwen , Li Jian-Feng , Li Ming-De , Yang Zhilin 
Published: October 2024

Abstract
Ultrafast all-optical control has been a subject of wide-spread attention as a method of manipulating optical fields using light excitation on extremely short time scales. As a fundamental form of ultrafast all-optical control, all-optical switching has achieved sub-picosecond switch speeds in the visible, infrared, and terahertz spectral regions. However, due to the lack of suitable materials, ultrafast all-optical control in the ultraviolet range remains in its early stages. We demonstrate sub-picosecond all-optical switching in the ultraviolet wavelength by designing a Si3N4-ITO Fabry–Pérot resonance aligns with the edge of the interband transition region of ITO. The response time of 500 fs achieved at a pump fluence as low as 0.17 mJ/cm2. Notably, unlike conventional binary switches (0, 1), this biphasic all-optical switch enables the modulation of optical intensity with positive, zero, and negative ΔR/R (0, 1, −1) at the same wavelength, all achieved with a switching speed of 680 fs at a pump fluence of 0.45 mJ/cm2. This work establishing a new pathway for all-optical control in the ultraviolet spectrum, the biphasic switch provides an extra degree of freedom for all-optical modulation.
The crystal structure of 4-chloro-2-formylphenyl 4-methylbenzenesulfonate, C14H11ClO4S
Authors: Liu Tao , Li Yang-Gang , Li Zhong-Yan , Yuan Lin 
Published: October 2024

Abstract
C14H11ClO4S, monoclinic, P21/c (no. 14), a = 8.2472(13) Å, b = 22.431(4) Å, c = 7.9308(13) Å, β = 106.278(2)∘, V = 1,408.3(4) Å3, Z = 4, Rgt
(F) = 0.0363, wRref
(F
2) = 0.0996, T = 296(2) K.
Geographic Tunnel Vision and the Past and Future of Democracy
Authors: Markoff John 
Published: October 2024

Abstract
In the twenty-first century, the democracy bequeathed by the past confronts major, diverse challenges. In thinking about how it might be reimagined, it is important to look beyond conceptions of democracy that are associated with a distinctive Western tradition, indicated at an early point by Athens two and a half millennia ago. Recent scholarship has questioned some clear connection of that specific ancient experience with the democracy that has developed since the late eighteenth century, challenging in several ways what might be called “epistemic exclusion.” One challenge concerns a long debate about Athenian uniqueness. A second concerns how the founding generation of modern democracy thought about, or did not think about, Athenian practices. A third concerns whether a broader geography of influence has infused the entire modern history of democracy in which much innovation has happened in peripheral places in hierarchies of wealth and power. These reflections have implications for where to look for good ideas to construct a better democratic future.
Materialversorgung effizient automatisieren
Authors: Schuler Lisa , Schneider Markus 
Published: October 2024

Abstract
Traditionally, assembly cells are supplied with materials manually by a logistics worker using a tugger train. The tasks include transporting, loading and unloading small load carriers. Alternatively, the supply can be fully automated. Three scenarios (manual with tugger train, automated with mobile cobot and automated with modified assembly cell structure) are tested in real life and compared in terms of effort, cost and efficiency and used to determine the efficient automated supply with rapid cost equalisation.
Fertigungsprozessanalyse eines mittels Innenhochdruck-Umformung hergestellten Bauteils
Authors: Reuter Thomas , Massalsky Kristin , Burkhardt Thomas 
Published: October 2024

Abstract
Series manufacturers in the field of hydroforming do not always have the necessary database for predictive maintenance, especially for the production of complex hydroformed components. Small and medium-sized companies in particular often lack the resources to acquire, process and profitably utilize these data sets under production conditions. The IHU processes that occur in practice are usually highly complex, both in terms of geometry and against the background of additional process steps (punching, plunging). This results in large amounts of data and complex data analyses, which are reflected in the data processing costs. A data analysis is to be carried out on the basis of a complex hydroforming process and its additional benefit for quality management and predictive maintenance is to be explained.
NPR3 is regulated by gonadotropins and modulates bovine cumulus cell expansion
Authors: De Cesaro Matheus P , de Macedo Mariana P , da Rosa Paulo R A , dos Santos Joabel T , Mea Ricardo D , da Nóbrega Janduí E , Duggavathi Raj , Gasperin Bernardo G , Gonçalves Paulo Bayard D , Bordignon Vilceu 
Published: October 2024

In briefThe natriuretic peptide system, particularly the C-type natriuretic peptide (CNP) and natriuretic peptide receptor 2 (NPR2), plays a critical role in regulating mammalian ovarian functions, including oocyte–cumulus cell communication and meiotic maturation. However, the contribution of natriuretic peptide receptor 3 (NPR3) to these processes has not been thoroughly investigated. Data from this study provide compelling evidence that NPR3 is involved in modulating gonadotropin signaling and regulating cumulus cell expansion in cattle.AbstractThe significant role of CNP and its receptor 2 (NPR2) in regulating oocyte meiotic maturation and facilitating communication between oocytes and surrounding cumulus cells has been well documented in various mammalian species including mice, cattle and swine. However, further investigation is needed to ascertain whether natriuretic peptide receptors (NPRs) are involved in regulating other essential ovarian functions. Hence, this study aimed to explore the potential involvement of NPRs in the regulation of cumulus expansion and oocyte meiotic maturation in bovine cumulus–oocyte complexes (COCs). The findings revealed that NPR3 mRNA abundance was downregulated by follicle-stimulating hormone and luteinizing hormone in cumulus cells of bovine COCs during in vitro maturation (IVM), while NPR2 mRNA levels were not affected by gonadotropins. Inhibition of the epidermal growth factor receptor (EGFR) during IVM of COCs prevented the NPR3 mRNA downregulation induced by gonadotropins in cumulus cells. Additionally, treatment of COCs during IVM with an NPR3 agonist (cANP4–23) inhibited cumulus expansion induced by gonadotropins. This inhibitory effect was further intensified when COCs were cotreated with cANP4–23 and CNP. These findings provide robust evidence indicating that normal cumulus expansion in bovine COCs involves an inhibitory effect of gonadotropins on NPR3 mRNA expression, which is mediated via EGFR signaling. The study also provides evidence that CNP and NPR3 interact synergistically to regulate cumulus expansion in response to gonadotropins.
The Hidden Metaphysics of J. M. E. McTaggart’s Paradox: Influence on The Analytic Philosophy of Time
Authors: Šulcas Adomas 
Published: October 2024

This paper discusses the various interpretations of McTaggart’s paradox that have been proposed throughout the 20th and the 21st centuries. It is argued that the traditional interpretation of McTaggart’s paradox, one which states that no metaphysical assumptions are required, is unfounded, but is nevertheless vital to the development of the analytic philosophy of time. To support such a position, various works of McTaggart and R. Ingthorsson are cited, aiming to show the intention of the creator of the paradox. It is argued that if McTaggart’s metaphysical premises are accepted, the potential number of interpretations gets narrowed down; however, it is also shown that many of the critiques and discussions arising from the analytic philosophy of time’s discourse can be relatively easily resolved. It is thus concluded that an interpretation of McTaggart’s paradox that includes his metaphysical premises not only makes the paradox itself less ambiguous, but it also shows the importance of metaphysics to the analytic philosophy of time.
Aristotle and the Problem of Universal Accessibility in Leisure
Authors: Deng Lianchong 
Published: October 2024

Leisure is both a necessary precondition for, and the ultimate purpose of, human activities. As such, it is commonly understood as a state of contemplation practiced for its own sake. However, this view raises a problem regarding its universal accessibility. Aristotle’s ethical and political theories demand leisure as a universally embraced way of life, while contemplative leisure appears impractical for common people. There are broadly two approaches to fix this problem: (a) distinguishing leisure of two sorts, and (b) expanding the semantic scope of contemplation. Nevertheless, they both come with certain limitations. I propose redefining leisure as a moral-psychological concept aligned with the allegedly hexis-state of the soul. This redefinition presents leisure as a basic human condition, offering a possible solution to the problem of its universal accessibility.
Natūrfilosofinės subjekto ir gamtos apibrėžtys: F. W. J. Schellingas ir I. H. Grantas
Authors: Junelis Domas 
Published: October 2024

Straipsnyje tyrinėjama subjekto ir gamtos samprata bei jų santykis F. W. J. Schellingo natūrfilosofijoje (Naturphilosophie), daugiausia remiantis šiuolaikine I. H. Granto interpretacija. Aiškinama, kad natūrfilosofija, subjektą traktuojanti kaip gaminamą gamtos, o pačią gamtą kaip absoliutų produktyvumą, tuo pačiu metu kritiškai atsigręžia į I. Kanto transcendentalinio idealizmo polinkį hipostazuoti subjektą jį atskiriant nuo gamtos. Straipsnyje taip pat teigiama, kad natūrfilosofija priartėja prie materialistinės logikos, pagal kurią subjektas, kaip gamtos produktyvumo produktas, yra vienas iš gamtos momentų, todėl jo pretenzijos galutinai apibrėžti gamtą yra nevaisingos. Teigiama, kad šis negalutinumas yra ne epistemologinio trūkumo pasekmė, bet pačios gamtos ir jos produktų ontologinė padėtis.
Rapid recovery after total hip arthroplasty: direct anterior approach combined with PENG block and lateral cutaneous femoral nerve block
Authors: Eremin I. K. , Daniliyants A. A. , Ermakova N. A. , Baysarov U. A. , Molarishvili Z. M. , Semenov N. A. , Zagorodniy N. V. 
Published: October 2024

Introduction The "gold" standard for the treatment of late stages of coxarthrosis is total hip arthroplasty. Direct anterior approach (DAA) refers to minimally invasive surgical interventions in orthopaedics. Extended anesthetic measures in combination with low-traumatic surgical techniques may reduce postoperative pain and accelerate patient's recovery.The purpose of the study was to compare the recovery times of patients after hip arthroplasty using DAA in combination with PENG block, lateral cutaneous femoral nerve (LCFN) block and without extended anesthetic measures.Materials and methods A prospective randomized comparative clinical study was performed, which involved 62 patients divided into two groups: the study one (n = 29) and the control one (n = 33). In both groups, arthroplasty was performed using DAA. Patients of the study group underwent PENG block and LCFN block. The patients in the control group did not receive extended anesthesia. The evaluation criteria were pain assessment using the visual analogue scale (VAS), administration of painkillers, patient’s mobility and the length of hospital stay.Results The VAS score for pain in the study group were lower than in the control group after 6 hours — 3.7 (3.4; 4.1) and 4.3 (4.2; 4.8); 24 hours after surgery — 3.5 (3.3; 3.6) and 4.1 (3.9; 4.5) (p < 0.001). After 48 hours, the indices were comparable: 3.5 (3.1; 4.1) and 3.7 (3.6; 3.9) (p = 0.19). The rate of requests for pain relief in the first 24 hours was lower in the study group than in the control group: 2 (1; 2) and 3 (2; 3) cases (p = 0.003). The results of the manual muscle test after 6 hours and 24 hours were comparable (p > 0.05). The time interval between the end of the operation and the first walking on crutches was shorter in the study group — 3.1 hours (2.9; 3.4) and 3.98 hours (3.8; 4.2) (p < 0.001). The length of hospital stay was shorter in the study group: 1.5 (1.2; 2) and 2.5 (2; 3) days (p < 0.001).Discussion Lower postoperative pain allows faster activation of patients, thus improving the results of the early rehabilitation period.Conclusion The use of PENG block and LCFN block in arthroplasty with the use of DAA has clinical effectiveness in the first 24 hours, and helps to accelerate the postoperative recovery of patients.
Clinical, functional and neuropsychological status of joint replacement patients
Authors: Dzhigkaev A. H. , Tynterova A. M. , Kozenkov I. I. , Khaibulin E. V. , Trofimova E. V. , Popadin K. Yu. , Gunbin K. V. , Goncharov A. G. 
Published: October 2024

Introduction The number of hip and knee replacement surgeries is increasing annually in Russia and worldwide. The majority of patients receiving joint arthroplasties are elderly women.The objective was to assess the clinical, functional and neuropsychological status of patients undergoing total knee or hip replacement.Material and methods The study included 448 patients admitted for elective surgery of total knee or hip replacement at the Department of Traumatology and Orthopedics of the Federal Center for High Medical Technologies (CHMT, Kaliningrad Region). Anthropometric parameters of the patients were measured, the medical history and concomitant diseases recorded. Common blood count and biochemistry test were evaluated preoperatively. Neuropsychological examination included assessment of cognitive and executive functions, levels of distress, depression, anxiety and somatization.Results Almost all patients studied were found to have varying degrees of obesity. A typical combination of concomitant pathology in volunteers was stage 2 hypertension, risk degree 2–3, and chronic gastritis in remission. Half of the volunteers showed moderate and high levels of distress, depression, anxiety and somatization. A significant number of volunteers showed moderate to high levels of cognitive decline. Age- and sex-related blood counts were slightly different from the normal ranges for a CBC and biochemistry. Changes in leukocyte count were detected.Discussion Leukocyte counts indicated the osteoarthritis induced inflammatory process in most patients. Mitochondrial dysfunction and aging of the immune system contributed to the “proinflammatory status.” The high rate of cognitive impairment in volunteers was associated with age and comorbidity, cardiovascular conditions, in particular. Distress and anxiety were associated with emotional reactions to surgery.Conclusion The factors reported can affect the duration and course of rehabilitation. The “pro-inflammatory status” of patients can complicate the healing of a postoperative wound. Neuropsychological disorders noted during postoperative rehabilitation can have a significant impact on physical recovery, social and professional adaptation.