bluuebunny/crossref_metadata_2025_split huggingface dataset:
The emergence of Fluoroquinolone resistant and Extended-spectrum beta-lactamase-producingSalmonella spp.isolated from Poultry in Pakistan
Authors: Irfan Rimsha , Uzair Bushra , Khan Eid Nawaz , Saeed Abdullah 
Published: October 2024

AbstractThe rise of antimicrobial-resistant and Extended Spectrum Beta Lactamases producingSalmonellastrains in poultry is a severe health threat worldwide, particularly in developing countries like Pakistan. The current study aimed to investigate the isolation and identification of Cefotaxime and Ciprofloxacin-ResistantSalmonellastrains originating from poultry. During this study, 78 (26.0%)Salmonellastrains were isolated from 300 diverse poultry samples. The isolated 78Salmonellastrains were identified asS. pullorum,S. gallinarum,S. enteritidis,S. enterica,S. paratyphi,S. typhimurium,S. typhi,S. arizonae,and 19% otherSalmonella spp. by API 20E method. The antibiotic susceptibility profile showed that 61% of MDRSalmonellastrains were isolated from diverse poultry samples. MDR rates were high in serovarsS. enterica,S. typhimurium,S. enteritidis,S. arizonae,andS. gallinarum. Co-resistant to cefotaxime and ciprofloxacin in 56.4% ofSalmonellastrains was observed. Among 44 phenotypically ESBL-positiveSalmonellastrains, 36 (81.8%) carriedblaCTX-M and 38 (86%) carriedblaCTX-M-1. A High incidence rate ofblaCTX-M andbla-CTX-M-1 was observed amongS. enteritidis(19% and 21%),S. enterica(11% and 16%),S. typhimurium(13% and16%) andS. typhi(3% and 5%). Among 29 phenotypically MBL-positiveSalmonellastrains, 13 (44.8%) carriedblaVIM and 6 (20.6%) carriedblaIMP. The 67% prevalence ofgyrA was observed in fluoroquinolone-resistantSalmonellastrains. The most prevalent fluoroquinolone strains wereS. enteritidis(19%),S. typhimurium(19%),S. typhi(13%), andS. gallinarum(12%). Fluoroquinolone-resistant, MBL, and ESBL-producingSalmonella strainsfrom poultry are a matter of great concern for both livestock and public health, demonstrating the dissemination risk of these microorganisms through the food chain.
Transcriptomic atlas of the morphologic development of the fungal pathogenCoccidioidesreveals key phase-enriched transcripts
Authors: Homer Christina M. , Voorhies Mark , Walcott Keith , Ochoa Elena , Sil Anita 
Published: October 2024

AbstractCoccidioides spp. are highly understudied but significant dimorphic fungal pathogens that can infect both immunocompetent and immunocompromised people. In the environment, they grow as multicellular filaments (hyphae) that produce vegetative spores called arthroconidia. Upon inhalation by mammals, arthroconidia undergo a process called spherulation. They enlarge and undergo numerous nuclear divisions to form a spherical structure, and then internally segment until the spherule is filled with multiple cells called endospores. Mature spherules rupture and release endospores, each of which can form another spherule, in a process thought to facilitate dissemination. Spherulation is unique toCoccidioidesand its molecular determinants remain largely unknown. Here, we report the first high-density transcriptomic analyses ofCoccidioidesdevelopment, defining morphology-dependent transcripts and those whose expression is regulated by Ryp1, a major regulator required for spherulation and virulence. Of approximately 9000 predicted transcripts, we discovered 273 transcripts with consistent spherule-associated expression, 82 of which areRYP1-dependent, a set likely to be critical forCoccidioidesvirulence. ChIP-Seq revealed 2 distinct regulons of Ryp1, one shared between hyphae and spherules and the other unique to spherules. Spherulation regulation was elaborate, with the majority of 227 predicted transcription factors inCoccidioidesdisplaying spherule-enriched expression. We identified provocative targets, including 20 transcripts whose expression is endospore-enriched and 14 putative secreted effectors whose expression is spherule-enriched, of which 6 are secreted proteases. To highlight the utility of these data, we selected a cluster ofRYP1-dependent, arthroconidia-associated transcripts and found that they play a role in arthroconidia cell wall biology, demonstrating the power of this resource in illuminatingCoccidioidesbiology and virulence.
Inconsistency of infant caretakers’ visual exposome with safe infant sleep recommendations: a systematic review and meta-analysis
Authors: de Visme Sophie , Pinhas Yaël , Cohen Jérémie F. , Moon Rachel Y. , Kanits Floortje , Plancoulaine Sabine , Sellier Anne-Laure , Harrewijn Inge , Gras-Le Guen Christèle , Chalumeau Martin 
Published: October 2024

ABSTRACTImportanceRates of sudden unexpected death in infancy (SUDI) remain high in several high-income countries. Several studies reported rates of pictures of sleeping infants or infant sleeping environments that were highly inconsistent with safe infant sleep recommendations (SISRs) to prevent SUDI.ObjectiveTo provide robust and synthetized evidence to decision-makers involved in corrective actions, we systematically assessed the proportion of pictures that were inconsistent with SISRs in the visual exposome of infant caretakers.Data SourcesIn November 2023, we searched PubMed, Web of Science, and Google Scholar.Study SelectionEligible studies included were those reporting the quantitative evaluation of the inconsistency between one or several SISRs and pictures depicting sleeping infants or a sleeping environment intended for an infant in physical and digital public spaces.Data Extraction and SynthesisData were extracted independently by 2 authors. The risk of bias of included studies was assessed with a customized version of Hoy’s tool for prevalence studies. A random-effects logistic regression model was used to obtain summary estimates of proportions of pictures. Between-study heterogeneity was estimated with theI2statistic.Main Outcomes(s) and Measure(s)The proportion of pictures inconsistent with one or several SISRs from the American Academy of Pediatrics.ResultsWe screened 1,086 articles and included 7 studies conducted between 2008 and 2023 that analyzed pictures found in parenting magazines, online and print newspapers, baby diaper packaging, commercial stock photography websites, and Instagram. The overall risk of bias was deemed low. Among the 5,442 pictures depicting sleeping infants or infant sleep environments, the summary estimates of the proportion of inconsistencies with SISRs were 39% for a non-supine sleeping position, 5% for a soft sleeping surface, 8% for sharing the sleeping surface, 14% for an unsafe crib, 58% for soft objects or loose bedding, 17% for a covered head, and 85% for at least one SISR inconsistency. All summary estimates had significant between-study heterogeneity.Conclusions and RelevanceInfant caretakers’ visual exposome is greatly inconsistent with SISRs and could lead to dangerous practices, which should prompt actions from manufacturers, advertisers, newspaper and website editors, social media moderators, and legislators.
Identification of lipid senolytics targeting senescent cells through ferroptosis induction
Authors: Zhang Lei Justan , Salekeen Rahagir , Soto-Palma Carolina , Elsallabi Osama , Ye Hongping , Hughes Brian , Zhang Borui , Nunes Allancer , Lee Kyooa , Xu Wandi , Mohamed Abdalla , Piepgras Ellie , McGowan Sara J. , Angelini Luise , O’Kelly Ryan , Han Xianlin , Niedernhofer Laura J. , Robbins Paul D. 
Published: October 2024

SUMMARYCellular senescence is a key driver of the aging process and contributes to tissue dysfunction and age-related pathologies. Senolytics have emerged as a promising therapeutic intervention to extend healthspan and treat age-related diseases. Through a senescent cell-based phenotypic drug screen, we identified a class of conjugated polyunsaturated fatty acids, specifically α-eleostearic acid and its methyl ester derivative, as novel senolytics that effectively killed a broad range of senescent cells, reduced tissue senescence, and extended healthspan in mice. Importantly, these novel lipids induced senolysis through ferroptosis, rather than apoptosis or necrosis, by exploiting elevated iron, cytosolic PUFAs and ROS levels in senescent cells. Mechanistic studies and computational analyses further revealed their key targets in the ferroptosis pathway, ACSL4, LPCAT3, and ALOX15, important for lipid-induced senolysis. This new class of ferroptosis-inducing lipid senolytics provides a novel approach to slow aging and treat age-related disease, targeting senescent cells that are primed for ferroptosis.
Small-amplitude synchronization in driven Potts models
Authors: Meibohm Jan , Esposito Massimiliano 
Published: October 2024

We study driven q-state Potts models with thermodynamically consistent dynamics and global coupling. For a wide range of parameters, these models exhibit a dynamical phase transition from decoherent oscillations into a synchronized phase. Starting from a general microscopic dynamics for individual oscillators, we derive the normal form of the high-dimensional Hopf bifurcation that underlies the phase transition. The normal-form equations are exact in the thermodynamic limit and close to the bifurcation. Exploiting the symmetry of the model, we solve these equations and thus uncover the intricate stable synchronization patterns of driven Potts models, characterized by a rich phase diagram. Making use of thermodynamic consistency, we show that synchronization reduces dissipation in such a way that the most stable synchronized states dissipate the least entropy. Close to the phase transition, our findings condense into a linear dissipation-stability relation that connects entropy production with phase-space contraction, a stability measure. At finite system size, our findings suggest a minimum-dissipation principle for driven Potts models that holds arbitrarily far from equilibrium.

Published by the American Physical Society
2024
Eyewitness memory for person, object and action information is mediated by interview environment and the presence or absence of rapport
Authors: Taylor Donna A. , J. Dando Coral 
Published: October 2024

Purpose
Obtaining accurate and reliable information from witnesses and victims of crime is essential for guiding criminal investigations and for the successful prosecution of offenders and beyond. Here, the purpose of this study is to investigate the impact of prosocial rapport behaviours and retrieval environment on mock eyewitness memory with an emphasis on the qualitative nature of information recalled in terms of persons, actions, objects and surroundings.

Design/methodology/approach
One hundred participants from the general population took part in mock witness research using a 2 (Environment: face-to-face; virtual) × 2 (Rapport: present; absent) design. Participants individually viewed an event depicting a fight in a bar and were then interviewed 48 h later according to condition.

Findings
Rapport and environment variously emerged as impactful, resulting in significant improvements in correct recall of persons, actions and object information when rapport was present and in virtual environments (VEs) when communicating via avatars. In many instances, the benefits of rapport and environment were additive, but not always. Surroundings information remained consistent across all conditions. Erroneous recall was extremely susceptible to inflation in face-to-face interviews when rapport was absent, in some instances increasing by over 100%. However, virtual interview spaces appeared to dilute the negative effects on retrieval when rapport was absent.

Research limitations/implications
This study concurs with others who have argued that comfortable witnesses are “better” witnesses; however, understanding what “comfort” looks and feels like remains a challenge.

Practical implications
The results, alongside the findings of others, have implications for applied and social cognition and reveal avenues for future research centred on widening access to justice and professional interview training.

Originality/value
This study reveals that prosocial rapport behaviours and VEs significantly enhance the accuracy of eyewitness recall. The findings suggest that virtual interviews can mitigate errors in the absence of rapport, offering valuable insights for criminal investigators and legal professionals. This research is crucial for improving witness interviewing techniques, thereby aiding in the accurate prosecution of offenders and broadening access to justice. The paper is valuable for criminal investigators, legal professionals, forensic psychologists and researchers focused on improving the reliability of eyewitness testimonies and interview methodologies.
Research trends of halal tourism: a bibliometric analysis
Authors: Ratnasari Ririn Tri , Sari Novi Sekar , Ahmi Aidi , Ismail Shafinar 
Published: October 2024

Purpose
The purpose of this study is to analyze studies on halal tourism in Scopus from 2010 to 2021 and reveal trends, impacts, the most influential articles and future research trends.

Design/methodology/approach
The study used data from Scopus in 2010 to 2021 with the topic of halal tourism and obtained 122 data publications. This study uses bibliometric analysis with Biblioshiny analysis tools.

Findings
Halal tourism attracts the attention of academics and practitioners. This study analyzed 122 publications from 2010 to 2021 in Scopus, showing an increase in author contributions of 39.1% per year, peaking in 2021. The most influential article was the work of Battour and Ismail (2016), which emphasized Islamic principles in halal tourism. Mohamed Battour is the lead author, with Indonesia and Malaysia as the leading countries. Future research trends include halal tourist motivation, marketing strategies, mobile applications and artificial intelligence in supporting halal tourism. Collaboration between halal destinations and other industries is also important.

Research limitations/implications
Database searches were only performed on Scopus, so publications not scanned here could not be analyzed. The search for data from this research is also only based on the title regarding halal tourism. Thus, another article that discusses halal tourism but does not have the word “halal tourism” in the title cannot be analyzed.

Originality/value
This research is different from previous research in that this study examines literature published in Scopus on the study of halal tourism from 2010 to 2021.
Financing mode decision of characteristic tourist town based on improved G1 and Z-number-TOPSIS: the Chinese case
Authors: Fang Lingmei 
Published: October 2024

PurposeThe objective is to address financing challenges with an innovative technical approach and provide financial support to facilitate the sustainable development of characteristic tourist towns.Design/methodology/approachIn this study, a novel decision model is proposed, which utilizes the CRITIC improved G1 weighting method to analyze financing factors and applies GRA to enhance the TOPSIS model under a Z-Number fuzzy environment. Finally, sensitivity analysis and comparative assessment were conducted to validate the findings and the model.FindingsThe findings indicate that equity financing is the optimal mode of financing for characteristic tourist towns, with bond financing serving as a viable alternative. Key factors influencing financing include economic benefit, social benefit and policy risk. Managers should carefully consider these factors when selecting financing methods in order to enhance efficiency and mitigate risks.Originality/valueAs a new business model and value creation method of cultural and tourism integration, the financing decision of a characteristic tourism town has always been the key to the overall promotion and operation. The research constructs a financing index system for characteristic tourism towns based on benefit and risk considerations, using the hot spring town in Anhui Province, China, as a case study to evaluate eight financing models.
Open innovation and internationalization of SMEs: a systematic literature review
Authors: TanTai Bingyan , Senik Zizah Che , Mat Isa Rosmah , Muhamad Nur Sa′adah 
Published: October 2024

Purpose
Open innovation (OI) significantly impacts the internationalization of small- and medium-sized enterprises (SMEs) by connecting them with external resources and accelerating their innovation processes. This study aims to systematically evaluate and synthesize existing knowledge on the role of OI in the internationalization of SMEs.

Design/methodology/approach
Through a systematic literature review method, this study critically evaluates 35 articles published between 2003 and 2023, synthesizing existing research from theoretical, contextual, characteristic and methodological perspectives.

Findings
This study identifies theoretical, methodological, characteristics and contextual research gaps and further proposes a research agenda for expanding knowledge in the field. Additionally, it provides an overview of the antecedents of OI adoption, SMEs internationalization outcomes and the influencing mechanisms of OI on SMEs internationalization found in the literature, thereby establishing a foundational knowledge base for future scholars and practitioners in this field.

Originality/value
This review contributes to the existing literature by consolidating current knowledge on the topic and advancing the understanding of the intersection between OI and the internationalization of SMEs.
The role of religious and financial factors in eudaimonic well-being among Indian adults
Authors: Padma Sri Lekha P. , Abdul Azeez E.P. , Sharma Jyoti , John Nijumon K. 
Published: October 2024

Purpose
The available literature has explored the various psychosocial determinants of well-being to some extent. The earlier works have focused primarily on hedonic well-being with little focus on eudaimonic aspects. Therefore, this study aims to understand the role of parent–child religious attendance during childhood, religious connectedness, and financial-material stability on eudaimonic well-being among adults in India.

Design/methodology/approach
The authors used the India data from Global Flourishing Study – Wave 1 that addressed flourishing among adults above 18 years. The authors considered 9,076 Indian adults and used descriptive and correlation statistics. In addition, the authors conducted path analysis and t-test.

Findings
The likelihood of eudaimonic well-being increased with parent–child religious attendance during childhood (ß = −0.044, p < 0.01) along with religious connectedness (ß = −0.112, p < 0.01) and financial-material stability (ß = 0.145, p < 0.01) as an adult. In addition, a significant difference existed in terms of religious connectedness and eudaimonic well-being with income and perceived feelings about income.

Originality/value
This study emphasizes financial stability’s relevance in well-being and suggests the importance of considering religious factors during childhood and adulthood. Emphasizing factors influencing eudaimonic well-being is relevant due to its influence on mental health and quality of life.
Research on the origin and evolution of technical management regulations for railway
Authors: Tian Lei , Sun Yuming , Jia Yonggang 
Published: October 2024

PurposeTo facilitate technical managers and field workers to master and understand the provisions of Technical Management Regulations for Railway more accurately, so as to better serve the comprehensive revision of the Regulations, this paper carries out the research on the traceability and evolution of the provisions of the Regulations.Design/methodology/approachThis paper studies and analyzes the evolution of the 11th edition of the Regulations by analyzing the relevance of clauses and summarizes the historical background of the development of calendar editions of the Regulations. The basic research on the traceability and evolution of the Regulations is carried out from four aspects: the continuity of the development of the Regulations, the authority of contents, the relevance of clauses and the richness of historical materials.FindingsFrom the first edition of the Regulations issued by the former Ministry of Railways in 1950 to the 11th edition, there have been ten comprehensive revisions. There is a strong correlation and continuity between the calendar editions of the Regulations in terms of chapter structure and clauses. Studying the context of the terms of the Regulations is an important way to understand and master the current clauses of the Regulations.Originality/valueThrough the research on the traceability and evolution of the clauses of the Regulations, one is to explore the context of the development of railway technical equipment in China, the other is to clarify the historical background when the provisions were formulated and the third is to trace the development and evolution of the provisions. The revision of the Regulations is based on an accurate grasp of the context of the provisions, which can effectively judge the possible security risks caused by the revision of the provisions and avoid the possible risks in field implementation from the source.
Hybridity as a governmental technique for designing and delivering NAPLAN in Australian schools
Authors: Savage Glenn C. , de Carvalho David 
Published: October 2024

AbstractThis paper explores the utility of hybrid governance as an analytical lens for understanding policy design and delivery in Australian schooling reform. Using the National Assessment Program in Literacy and Numeracy (NAPLAN) as a case study, we argue that its design and delivery processes exemplify hybridity in myriad dimensions. In a federal system in which national schooling reform relies upon negotiation and consensus building amongst a multiplicity of government and non‐government stakeholders, we argue that NAPLAN's hybridity serves as a governmental technique for managing and sustaining collaborative governance arrangements. Hybridity also supports the standardised implementation of the assessment across diverse schooling systems and sectors. While NAPLAN's hybridity generates strategic benefits for Australian governments, it also produces risks. A challenge for policymakers is to harness its benefits while ensuring transparent decision‐making and clear responsibilities and accountabilities. To address risks and leverage opportunities, we argue there are benefits to having a convening agency with authority to manage and sustain hybrid networks at the national scale.Points for practitioners
Hybrid governance offers productive insights into how Australian governments work collaboratively to design and deliver national schooling reforms.
The National Assessment Program in Literacy and Numeracy (NAPLAN) is an exemplary case study for examining hybrid governance in the Australian federation.
Hybrid governance serves as a technique for managing and sustaining collaborative governance arrangements at the national scale and for ensuring NAPLAN's implementation is standardised across Australia's diverse subnational schooling systems and sectors.
Hybridity creates risks and opportunities. A challenge for policymakers is to harness its benefits while ensuring transparent decision‐making and clear responsibilities and accountabilities.
There are benefits to having a convening agency with authority to manage and sustain hybrid networks at the national scale.