bluuebunny/crossref_metadata_2025_split huggingface dataset:
Βιβλιοπαρουσίαση: Ελένη Λοΐζου (2021). «Το παιχνίδι στην προσχολική εκπαίδευση. Η αλληλένδετη σχέση του με τη μάθηση και την ανάπτυξη». Πεδίο
Authors: Συμεωνίδου Σιμώνη 
Published: October 2024

«Τα παιδία παίζει» λέει η γνωστή μας έκφραση. Αλλά τι σημαίνει η έκφραση αυτή για τον καθένα και την καθεμιά; Για κάποιους σημαίνει ότι τα παιδιά είναι φτιαγμένα για να παίζουν. Για άλλους σημαίνει ότι μπορεί τα παιδιά να παίζουν, αλλά άλλο το παιχνίδι, και άλλο η μάθηση. Κάποιοι άλλοι χρησιμοποιούν την έκφραση ειρωνικά, όταν οι ενήλικες παίζουν. Το βιβλίο της Ελένης Λοΐζου «Το παιχνίδι στην προσχολική εκπαίδευση. Η αλληλένδετη σχέση του με τη μάθηση και την ανάπτυξη» απαντά στα πιο πάνω ερωτήματα αλλά και σε πολλά άλλα και συνδέει τη θεωρία με την πράξη με τον καλύτερο δυνατό τρόπο.
On the interrelationships between Iraqi EFL learners’ classroom environment, foreign language classroom anxiety and willingness to communicate: A SEM approach
Authors: Abdulkareem Obaid Alyaa , Zeraatpishe Mitra , Faravani Akram 
Published: October 2024

Different factors play their roles in communication especially when the concern is a foreign language such as classroom environment, foreign language classroom anxiety and willingness to communicate. The purpose of the present study is to investigate the relationship among EFL Iraqi learner’s classroom environment, foreign language classroom anxiety and willingness to communicate. First, from among the available 260 English university students at Babylon university, 204 EFL intermediate language learners who studied English language were selected. The selection was based on their score in Cambridge Quick Placement Test 2004(QPT). The participants, then filled three questionnaires of anxiety, classroom environment, and willingness to communicate. The three questionnaires were filled out by the participants. To consider the extent of the interrelationships among classroom environment, willingness to communicate and speaking anxiety, a model of associations among them was proposed. To analyze the obtained data, structural equation modelling (SEM) was used and the model was probed using AMOS. Results of SEM indicated a complete fit and significant interrelationship among the variables were found. The findings have several implications for EFL teachers and learners.
Development of a prediction model for 30-day COVID-19 hospitalization and death in a national cohort of Veterans Health Administration patients–March 2022—April 2023
Authors: Bui David P. , Bajema Kristina L. , Huang Yuan , Yan Lei , Li Yuli , Rajeevan Nallakkandi , Berry Kristin , Rowneki Mazhgan , Argraves Stephanie , Hynes Denise M. , Huang Grant , Aslan Mihaela , Ioannou George N. 
Published: October 2024

Objective
The epidemiology of COVID-19 has substantially changed since its emergence given the availability of effective vaccines, circulation of different viral variants, and re-infections. We aimed to develop models to predict 30-day COVID-19 hospitalization and death in the Omicron era for contemporary clinical and research applications.

Methods
We used comprehensive electronic health records from a national cohort of patients in the Veterans Health Administration (VHA) who tested positive for SARS-CoV-2 between March 1, 2022, and March 31, 2023. Full models incorporated 84 predictors, including demographics, comorbidities, and receipt of COVID-19 vaccinations and anti-SARS-CoV-2 treatments. Parsimonious models included 19 predictors. We created models for 30-day hospitalization or death, 30-day hospitalization, and 30-day all-cause mortality. We used the Super Learner ensemble machine learning algorithm to fit prediction models. Model performance was assessed with the area under the receiver operating characteristic curve (AUC), Brier scores, and calibration intercepts and slopes in a 20% holdout dataset.

Results
Models were trained and tested on 198,174 patients, of whom 8% were hospitalized or died within 30 days of testing positive. AUCs for the full models ranged from 0.80 (hospitalization) to 0.91 (death). Brier scores were close to 0, with the lowest error in the mortality model (Brier score: 0.01). All three models were well calibrated with calibration intercepts <0.23 and slopes <1.05. Parsimonious models performed comparably to full models.

Conclusions
We developed prediction models that accurately estimate COVID-19 hospitalization and mortality risk following emergence of the Omicron variant and in the setting of COVID-19 vaccinations and antiviral treatments. These models may be used for risk stratification to inform COVID-19 treatment and to identify high-risk patients for inclusion in clinical trials.
Care-related quality of life of informal caregivers of stroke survivors: Cross-sectional analysis of a randomized clinical trial
Authors: Villa-García Lorena , Salvat-Plana Mercè , Slof John , Pérez de la Ossa Natalia , Abilleira Sònia , Ribó Marc , Hidalgo-Benítez Verónica , Inzitari Marco , Ribera Aida 
Published: October 2024

Purpose
We aimed to describe the intensity of care and its consequences on informal caregivers of stroke survivors according to the degree of care receivers’ functional dependence for activities of daily living; and to identify the factors associated with caregivers’ care-related quality of life.

Methods
Cross-sectional analysis of prospective data collected in a cost-utility study alongside the RACECAT trial in Catalonia (Spain). One-hundred and thirty-two care receiver-caregiver pairs were interviewed six months after stroke. Functional dependence for activities of daily living was measured with the Barthel index. We assessed caregivers care-related quality of life with the CarerQoL, which measures seven dimensions of subjective burden (CarerQoL-7D) and a happiness score (CarerQoL-VAS). We evaluated the association between characteristics of informal caregivers, characteristics of care receivers, and intensity of care, and the caregiver’s care-related quality of life (subjective burden and happiness) in a hypothesized model using a structural equation model.

Results
Of the 132 caregivers, 74,2% were women with an average age of 59.4 ± 12.5 years. The 56.8% of them were spouses. The care intensity ranged from a mean of 24h/week for mild to 40h/week for severe dependence. Most caregivers (76.3%) were satisfied with their task, regardless of dependence, but showed increasing problems in caring for severely dependent persons. Being a woman (coeff. -0.23; 95%CI: -0.40, -0.07), spending more time in care tasks (coeff -0.37; -0.53, -0.21) and care receiver need of constant supervision (coeff 0.31; -0.47, -0.14) were associated with higher burden of care, irrespective of the degree of dependence. Caregiver burden (coeff 0.46; 0.30–0.61) and care receiver anxiety or depression (coeff -0.19; -0.34, -0.03) were associated with lower caregiver happiness.

Conclusions
The findings suggest the importance of developing mainly two types of support interventions for caregivers: respite and psychosocial support. Especially for women with high caring burden and/or caring for persons with high levels of anxiety or depression.
Identifying individuals at high risk for dementia in primary care: Development and validation of the DemRisk risk prediction model using routinely collected patient data
Authors: Reeves David , Morgan Catharine , Stamate Daniel , Ford Elizabeth , Ashcroft Darren M. , Kontopantelis Evangelos , Van Marwijk Harm , McMillan Brian 
Published: October 2024

Introduction
Health policy in the UK and globally regarding dementia, emphasises prevention and risk reduction. These goals could be facilitated by automated assessment of dementia risk in primary care using routinely collected patient data. However, existing applicable tools are weak at identifying patients at high risk for dementia. We set out to develop improved risk prediction models deployable in primary care.

Methods
Electronic health records (EHRs) for patients aged 60–89 from 393 English general practices were extracted from the Clinical Practice Research Datalink (CPRD) GOLD database. 235 and 158 practices respectively were randomly assigned to development and validation cohorts. Separate dementia risk models were developed for patients aged 60–79 (development cohort n = 616,366; validation cohort n = 419,126) and 80–89 (n = 175,131 and n = 118,717). The outcome was incident dementia within 5 years and more than 60 evidence-based risk factors were evaluated. Risk models were developed and validated using multivariable Cox regression.

Results
The age 60–79 development cohort included 10,841 incident cases of dementia (6.3 per 1,000 person-years) and the age 80–89 development cohort included 15,994 (40.2 per 1,000 person-years). Discrimination and calibration for the resulting age 60–79 model were good (Harrell’s C 0.78 (95% CI: 0.78 to 0.79); Royston’s D 1.74 (1.70 to 1.78); calibration slope 0.98 (0.96 to 1.01)), with 37% of patients in the top 1% of risk scores receiving a dementia diagnosis within 5 years. Fit statistics were lower for the age 80–89 model but dementia incidence was higher and 79% of those in the top 1% of risk scores subsequently developed dementia.

Conclusion
Our models can identify individuals at higher risk of dementia using routinely collected information from their primary care record, and outperform an existing EHR-based tool. Discriminative ability was greatest for those aged 60–79, but the model for those aged 80–89 may also be clinical useful.
The Relationship between Regime ‘Type’ and Civic Education: The Cases of Three Chinese Societies, Hui Li (2021)
Authors: Chen Sicong 
Published: October 2024

Review of: The Relationship between Regime ‘Type’ and Civic Education: The Cases of Three Chinese Societies, Hui Li (2021)
Singapore: Springer, 159 pp.,
ISBN 978-9-81165-233-2, e-book, £67.55
Gallstone Disease Is Associated With an Increased Risk of Inflammatory Bowel Disease: Results From 3 Prospective Cohort Studies
Authors: Mi Ningning , Yang Man , Wei Lina , Nie Peng , Zhan Shukai , Nguyen Long H. , Smith Fang Gao , Acharjee Animesh , Liu Xudong , Huang Junjie , Xia Bin , Yuan Jinqiu , Meng Wenbo 
Published: October 2024

INTRODUCTION:
Gallstone diseases affect intestinal inflammation, bile flow, and gut microbiota, which in turn may increase the risk of inflammatory bowel disease (IBD). However, epidemiological studies exploring the associations between gallstone diseases and subsequent IBD risk have been limited.

METHODS:
This is a combined analysis of 3 prospective cohort studies (Nurses' Health Study, Nurses' Health Study II, and UK Biobank) and replicated in a case-control study (Chinese IBD Etiology Study). We evaluated the hazard ratios (HRs)/odds ratios (ORs) between gallstone diseases with IBD risk by Cox logistic regression or conditional logistic regression, adjusting for demographic characteristics, lifestyles, comorbidities, and medication usage.

RESULTS:
We identified 3,480 cases of IBD over 2,127,471 person-years of follow-up in the 3 cohort studies. The participants with gallstone disease had a 38% increase in the risk of IBD (HR 1.38, 95% confidence intervals [CI] 1.21–1.59), 68% increase in Crohn's disease (HR 1.68, 95% CI 1.38–2.06), and 24% increase in ulcerative colitis (HR 1.24, 95% CI 1.03–1.49). In Chinese IBD Etiology Study, we found even larger magnitude of effects between gallstone diseases and IBD risk (IBD: OR 3.03, 95% CI 2.32–3.97; Crohn's disease: OR 5.31; 95% CI 3.71–7.60; ulcerative colitis: OR 1.49; 95% CI 1.07–2.06). There were no major differences in the estimated associations between the presence of unremoved gallstones and prior cholecystectomy with IBD risk.

DISCUSSION:
Gallstone disease was linked to an increased risk of IBD and its subtypes, independent of traditional risk factors. Further research is needed to confirm these associations and clarify the underlying biological mechanisms.
Liver Dysfunction and Systemic Inflammation Drive Organ Failures in Acute Decompensation of Cirrhosis: A Multicentric Study
Authors: Verma Nipun , Roy Akash , Valsan Arun , Garg Pratibha , Ralmilay Samonee , Girish Venkitesh , Kaur Parminder , Rathi Sahaj , De Arka , Premkumar Madhumita , Taneja Sunil , Goenka Mahesh Kumar , Duseja Ajay 
Published: October 2024

INTRODUCTION:
Hospitalized patients with acute decompensation (AD) of cirrhosis are at risk of progressing to acute-on-chronic liver failure (ACLF), significantly increasing their mortality. The aim of this study was to identify key predictors and patient trajectories predisposing to ACLF.

METHODS:
In this multicenter, prospective study spanning 2 years, clinical, biochemical, and 90-day survival data were collected from 625 patients with AD (European Association for the Study of the Liver criteria) across North, South, and East India. We divided the cohort into a Derivation cohort (DC: 318 patients) and a Validation cohort (VC: 307 patients). Predictive models for pre-ACLF were derived, validated, and compared with established scores such as model for end-stage liver disease (MELD) 3.0 and chronic liver failure Consortium acute decompensation.

RESULTS:
Of 625 patients (mean age 49 years, 83% male, 77.5% with alcohol-related liver disease), 32.2% progressed to ACLF. Patients progressing to ACLF showed significantly higher bilirubin (10.9 vs 8.1 mg/dL), leukocyte counts (9,400 vs 8,000 per mm3), international normalized ratio (1.9 vs 1.8), and MELD 3.0 (28 vs 25) but lower sodium (131 vs 134 mEq/L) and survival (62% vs 86%) compared with those without progression (P < 0.05) in the DC. Consistent results were noted with alcohol-associated hepatitis, infection and hepatic encephalopathy as additional risk factors in VC. Liver failure at presentation (odds ratio: 2.4 [in DC], 6.9 [in VC]) and the 7-day trajectories of bilirubin, international normalized ratio, and MELD 3.0 significantly predicted ACLF progression (P < 0.001). A new pre-ACLF model showed superior predictive capability (area under the curve of 0.71 in DC and 0.82 in VC) compared with MELD 3.0 and chronic liver failure Consortium acute decompensation scores (P < 0.05).

DISCUSSION:
Approximately one-third of AD patients in this Indian cohort rapidly progressed to ACLF, resulting in high mortality. Early identification of patients at risk can guide targeted interventions to prevent ACLF.
Method for the design and evaluation of binary sensitivity tests
Authors: Wilrich Cordula , Wilrich Peter-Th. 
Published: October 2024

Abstract
For many materials or specimen, their resistance to stress is an important (safety) characteristic. The target value is the event stress, i.e., the value of the stress at which the (adverse) event occurs. Depending on the test procedure and the test items, the event stress cannot always be measured directly but must be determined by binary sensitivity tests. A method for the evaluation of binary sensitivity tests based on the principle of Maximum Likelihood is presented and compared to other methods (traditionally) applied. Sensitivity testing of explosives and fatigue testing of metallic materials are used as real examples to illustrate application of the method and to compare actual results. The method presented delivers not only the estimate of the stress at any specified probability of the event but also the respective 95 % confidence interval. Application of the method is facilitated because it does not require the data to be obtained in a staircase procedure, can process any kind of input data (e.g., as measured or logarithmic), and does not require the stress levels to be equidistant. The method is easily applicable for any laboratory because it is implemented into an Excel file, which is made freely available at https://www.statistics-wilrich.info.
El nuevo gobierno de Milei y China
Authors: Villasenin Lucas 
Published: October 2024

Resumen
La llegada al gobierno de Javier Milei en Argentina constituye una novedad para la historia política argentina y también para el análisis de las relaciones con la República Popular China. El gobierno que comenzó el 10 de diciembre de 2023 es un resultado de la profunda crisis económica que atraviesa el país y de la habilidad del líder libertario de sumar apoyos a partir del descontento social. Este cambio de gobierno vino de la mano de un marcado cambio en materia de política internacional para el Estado argentino. Las tensiones abiertas por el nuevo presidente que sistémicamente declara en contra del gobierno chino ponen en riesgos los avances obtenidos en 52 años de relaciones bilaterales entre ambos países. El acelerado desarrollo del vínculo sino-argentino en las últimas décadas actualmente se ve afectado por decisiones como el rechazo a incorporarse al bloque ampliado de los BRICS o mantener vínculos con funcionarios en Taiwan de China. En este artículo se destacan las implicancias concretas de la llegada de Milei al Gobierno para la relación bilateral entre ambos países y se analizan las perspectivas futuras en función de la dinámica global en curso.
Synthesis, structure and optically limiting NLO properties of a distorted cubane-like cluster (µ-Cl)(µ
3-WSe4)(CuPPh3)3
Authors: Chen Meng-Ting , Liang Qing-Wen , Pan Song , Jia Ai-Quan , Zhang Qian-Feng 
Published: October 2024

Abstract
Treatment of [Et4N]2[WSe4] with three equivalents of CuCl and PPh3 (Ph = phenyl) in a mixed solvent of 25 mL of CH2Cl2 and 5 mL of DMF afforded a distorted cubane-like cluster [(µ-Cl)(µ
3-WSe4)(CuPPh3)3] (1), which has been structurally characterized by single-crystal X-ray diffraction. The coordination geometry of the tungsten center and two copper atoms is tetrahedral, whereas that of the other copper atom is triangular. Regarding the NLO properties, a large optical limiting effect with a threshold of 0.91 J cm−2 was observed with laser pulses of 7 ns at 532 nm.
Cosméticos com presença de disruptores endócrinos e gestação: percepção de risco pelos profissionais de saúde
Authors: Souza Laís dos Santos Rocha , Oliveira Neta Ana Izabel de , Gomes Júlia Souza , Andrade e Silva Érika , Emidio Suellen Cristina Dias , Paraiso Alanna Fernandes 
Published: October 2024

Objetivo: conhecer a percepção dos profissionais de saúde da Atenção Primária à Saúde quanto aos riscos associados ao uso de cosméticos que contêm disruptores endócrinos durante a gestação. Métodos: trata-se de um estudo qualitativo. Os participantes foram 17 profissionais de saúde que fazem consultas às gestantes na Atenção Primária à Saúde. A coleta de dados ocorreu por meio de entrevista semiestruturada. Para a análise das entrevistas, contou-se com a Análise de Conteúdo, e com referenciais teóricos de pesquisadores da área. Resultados: observou-se que há pouco conhecimento da maioria dos participantes sobre o conceito de disruptores endócrinos, os quais relataram pouca segurança para recomendarem, ou não, sobre o uso de cosméticos e produtos de higiene pessoal e, ainda, poucos demonstraram conhecer os riscos que possam apresentar à saúde. Conclusão: os profissionais de saúde mostraram que há uma fragilidade quanto ao seu conhecimento sobre os riscos dos disruptores endócrinos presentes nos cosméticos, e, consequentemente, encontram dificuldades para orientar as gestantes a reduzirem as exposições prejudiciais. Contribuições para a prática: sensibilização dos profissionais para a necessidade constante de atualizações para prestarem aconselhamento com segurança às gestantes.
Improving Time to Goals of Care Discussions in Invasively Ventilated Preterm Infants
Authors: Gentle Samuel J. , Cohen Charli , Carlo Waldemar A. , Winter Lindy , Hallman Madhura 
Published: October 2024

BACKGROUND AND OBJECTIVES
The challenge of identifying preterm infants with bronchopulmonary dysplasia (BPD) that need tracheostomy placement may delay goals of care (GOC) discussions. By identifying infants with a low probability of ventilation liberation, timely GOC discussions may reduce the time to tracheostomy. Our SMART aim was to reduce the postmenstrual age (PMA) of GOC discussions by 20% in infants with BPD and prolonged invasive ventilatory requirement by October 2020.

METHODS
Our group conducted a quality improvement initiative at the University of Alabama at Birmingham. Infants were included if born at &lt;32 weeks’ gestation and exposed to invasive ventilation for ≥2 weeks beyond 36 weeks’ PMA. Interventions included (1) consensus of BPD infants at risk for tracheostomy dependence, (2) monthly multidisciplinary tracheostomy meetings, and (3) development and utilization of tracheostomy educational content for families. Statistical process control charts were used for all analyses.

RESULTS
A total of 79 infants were included in analyses, of which 44 infants either received a tracheostomy or died. From X-mR control chart analysis, there was special cause variation in the time to GOC discussions, which decreased from 62 to 51 weeks’ PMA related to monthly multidisciplinary conferences. The average PMA at tracheostomy decreased from 80 weeks to 63 weeks with no change in the frequency of tracheostomy placement or discordant GOC discussions in which infants survived to hospital discharge without a tracheostomy.

CONCLUSIONS
In infants with ventilator-dependent BPD, standardization of GOC discussions reduced the PMA of GOC discussions and tracheostomy.
UTILIZATION OF SHRIMP HEAD AND FISH BONE MEAL FROM FISHERIES WASTE AS LOCAL FISH FEED INGREDIENTS IN LINGGA
Authors: Agriandini Maulina , Purnamasari Tina , Kartika Nurmayuni , Tartila Shobrina Silmi Qori , Oktary Rini , Pratiwi Lastri , Rahayu Sri Panca 
Published: October 2024

The problem faced by fish farmers in Lingga is that the feed is quite expensive and rarely found on the local market. The existence of shrimp heads and fish bones are often found in Dabo as waste from processed shrimp crackers and fish balls that have not been utilized. The research aimed to evaluate the quality of fish feed from local fish meal, shrimp head meal and fish bone meal based on organoleptic, physical, and chemical tests. The treatments tested in this study consist of three threatments, namely: feed A (48%), feed B (35%), and feed C (comercial feed). The organoleptic showed that feed have a fibrous texture, typical coconut aroma, and brown color. The results of water stability showed that feed A (86,50 minutes±1,63), B (87,00 minutes±1,29), C (91,75 minutes±0,96) and dispersion of solids feed A (9,38% ±0,95), B (9,50%±0,71), C (8,63%±0,85). The sinking velocity showed that feed A (3,79 cm/s±0,23), B (3,32 cm/s±0,24), C (4,61 cm/s±0,18). The hardness level of feed A (91,63%±1,38), B (91,38%±2,66), C (94,63%±2,14). The proximate of feed has a moisture of 7,53% (A); 5,28% (B); 6,69% (C), ash of 19,95% (A); 17,85% (B); 12,03% (C), crude protein of 49,07% (A); 36,14% (B); 31,23% (C), crude lipid of 4,28% (A); 4,90% (B); 11,63% (C), and carbohydrate 19,19% (A); 35,84% (B); 38,43% (C). The results of physical and proximate indicated that ingredients local feedstuff have the potential as fish feed except moisture and ash.
On the problem of neuropathic pain component diagnosis in patients with cancer pain syndrome
Authors: Spasova A. P. , Dorozhenko A. M. , Ryazankina A. A. , Barysheva O. Yu. , Burganova A. N. , Goncharova E. V. 
Published: October 2024

Neuropathic pain component occurs in every second patient with pain syndrome caused by a malignant tumor. Detection of the neuropathic component of pain syndrome is crucial for selection of effective analgesia.The review presents an application algorithm for an updated system of neuropathic pain component assessment in oncological patients.