bluuebunny/crossref_metadata_2025_split huggingface dataset:
MENGURAI KOMPLEKSITAS PENGELOLAAN KOINFEKSI TUBERKULOSIS PADA PENDERITA HUMAN IMMUNODEFICIENCY VIRUS (HIV): TANTANGAN DAN SOLUSI TERKINI
Authors: Rosfita Alfy Rizka Silfa , Marpaung Rie Dahniar Marissa , Syakira Rojwa Azka 
Published: October 2024

Tuberkulosis (TB) adalah infeksi oportunis pada pasien dengan HIV yang menjadi salah satu penyebab utama kematian di seluruh dunia. Koinfeksi TB-HIV terjadi ketika seseorang mengidap TB kemudian terinfeksi HIV pada saat yang bersamaan. pasien dengan infeksi HIV positif memiliki risiko empat kali lebih tinggi mengalami kegagalan pengobatan TB dibandingkan pasien dengan HIV negatif. Sumber data utama dalam penelitian ini adalah publikasi ilmiah yang relevan dengan topik koinfeksi TBC dan HIV. Indonesia baru mencapai 73% dari 90% target keberhasilan pengobatan TB pada tahun 2021. Perkembangan kasus TB multidrug drug resistant (MDR) dan extensively drug resistant (XDR) merupakan tantangan yang dihadapi oleh para klinisi saat menangani HIV. terkait skrining dan diagnosis pasien TB dengan HIV, perlu dilakukan dengan teliti dan efektif. Pemeriksaan meliputi pemeriksaan mikroskopis, uji kultur, GeneXpert, Line Probe Assay, LAM. Penelitian berkualitas tinggi juga harus dilakukan mengenai perpanjangan pengobatan pada ODHA (Orang Dengan HIV/AIDS) TB resisten. Profilaksis diberikan untuk mencegah terjadinya infeksi oportunistik yang umum terjadi di antara orang yang hidup dengan HIV, dan dianjurkan di antara orang dengan koinfeksi TB/HIV dalam kombinasi dengan terapi antiretroviral (ART). Berbagai upaya sangat diperlukan untuk mengatasi faktor risiko serta mengurangi kegagalan pengobatan TB. Perlu adanya penelitian selanjutnya untuk dapat mengembangkan penelitian-penelitian ini dengan strategi yang lebih inovatif dan efektif dalam pengelolaan koinfeksi TBC-HIV, khususnya dalam mengatasi resistensi obat dan meningkatkan kualitas hidup ODHA
Molecular Detection and Phylogenetic Tree of Rotavirus from Human and Sheep, Iraq
Authors: Mayea Khetam Qaid , Sadeq Jenan Nadhim , Neamah Azhar Abdulsada 
Published: October 2024

Group A rotaviruses (RVA) have been linked to acute gastroenteritis in children, as well as young domestic and wild animals. In Iraq few molecular studies involved the genotype profile of rota virus and this is the first study target VP1 gene. Data were collected from January to February 2018 and subsequently examined utilizing a PCR and because of low viral concentration we utilized Nested PCR. Sequenced PCR result at 327 bp fragment in 4 A rota virus-positive samples deposited in GenBank under accession number (MH11809.1, MH118097.1) for human and (MH118095.1, MH118094.1) to sheep. Children samples were identical to the other human A rota virus at (99-100%), with Japan feline-like human G6P and G6P[14] isolated from cattle as well as, animal rota virus (99-100%) similarity with cross relation with human Wa-Like and porcine, moreover Morocco characterized caprine, bovine rotavirus and Slovenian Roe deer ARV.
Health Dietary Program for Patient after Sleeve Gastrectomy: Case - Control Study
Authors: Mohammed Ahmed Harbi , Jawad Huda Baker Hassan 
Published: October 2024

Background: In general, obesity has been increasing at an alarming rate over the past 50 years. In 2022, obesity and its comorbidities accounted for 14.3 percent of this world healthcare expenditure. Weight loss surgery is considered a safe and durable treatment option for obesity. The techniques have been continuously evolving to yield better outcomes. The studies showed that post-operative complications increased with physical inactivity and therefore reduces patient’s quality of life (1), The Gastroenterology Endoscopic Department Al-Kindy-Teaching Hospital – Baghdad-Iraq (2019), mentioned that dietary habits play a significant role in the development of gastrointestinal disorders(2). so that this activity describes the dietary program after sleeve gastrectomy and highlights the role of the interprofessional team in the management of patients with obesity. and the extent to which a patient's behavior conforms to the instructions given by health practitioners (3). Objective: To find out the effectiveness of rehabilitation program on patient's nutritional status after sleeve gastrectomy, to find out the relationship between patient's nutritional status and demographic characteristics (age, sex, and level of education). Material and Methods: The design used in the current study is a quasi-experimental design -experimental design (two -groups comparison), the study was conducted in center of hepatopathy and digestive diseases in AL-Hussein Teaching Hospital at AL-Muthanna city in Iraq. Study Sample: A non-probability (purposive) sample was taken from patients who performed gastric sleeve and the sample was (50) patients. Use questionnaire in this study. Result: It was found that there is an effectiveness of the program on the case group with the post-test when compared with the control group after implementation program. Conclusion: The patient after sleeve gastrectomy have inadequate knowledge concerning dietary. The program which implemented on patients had a benefit feedback on patients.
Comparison study between Sevoflurane/Remifentanil with Isoflurane/Remifentanil to induce hypotension in Rhinoplasty Operations
Authors: Ahmed Rawa Azad , Al-dabbagh Dr. Abdulhameed , Fadhel Dr. Rekawt 
Published: October 2024

Background: Answering the question of “which modality and combination is having the upper handy?” in bleeding control during rhinoplasty surgery through controlled hypotension achieved by administering anesthesia with two different inhalation agents: sevoflurane or isoflurane, both in combination with remifentanil. Numerous studies and articles are published annually, yet the wider question regarding the efficacy of each formula has remained unaddressed.
Methods: This prospective observational study utilized convenient sampling with a total of 100 patients undergoing rhinoplasty. Participants were divided into two groups: one receiving remifentanil combined with sevoflurane and the other receiving remifentanil combined with isoflurane. Controlled hypotension was achieved and monitored throughout the procedure.
Results: Both anesthesia combinations effectively achieved controlled hypotension and created a dry operative field. Notably, the sevoflurane/remifentanil combination resulted in a faster onset of decreased heart rate and mean arterial blood pressure (MAP) within the first 40 minutes of the procedure compared to the isoflurane/remifentanil combination.
Conclusion: The study demonstrated that both sevoflurane/remifentanil and isoflurane/remifentanil combinations are effective in controlling bleeding during rhinoplasty. Sevoflurane/remifentanil showed a quicker initial effect on cardiovascular parameters, but both protocols successfully met the primary goal of minimizing bleeding and enhancing surgical visibility.
Correlation of Recombinant FSH Doses with Follicular and Serum Level Resolvin E1 in Polycystic Ovarian Syndrome Women Undergoing ICSI
Authors: Mohammed Muna Rasool Abdulzahraa Amal Abdulwahid 
Published: October 2024

Background: Reproduction is a intricately structured process achieved by interaction of the higher centers in the brain, the gonads, and different body parts; Whereas infertility is a multifactorial pathological condition affecting approximately 10–15% of couples, especially in industrialized region.RESOLVIN E1 is a member of specialized pro resolving mediator family of bio active lipids. It has anti-inflammatory effects in various inflammatory diseases. A promising researches in their way to prove its positive role in reproduction through direct effect on folliculogenesis. It has a fundamental role in regulating follicular growth and maturation at central and peripheral levels highlighting its possible role in diagnosing and treating infertility problems. High level of RESOLVIN E1 which might play critical role in poly cystic ovarian syndrome due to its anti-inflammatory effects. Objectives: To investigate the correlation of serum and follicular RESOLVIN E1 to gonadotropin (recombinant FSH doses) in PCOS patient undergoing ICSI. Subject, Patients, Materials, and Method: A prospective cross-sectional study conducted in the high institute for infertility diagnosis and assisted reproductive technology /Al Nahrain University /Baghdad /Iraq, from November 2023 till March 2024. Twenty-nine infertile PCOS women who were undergoing intracytoplasmic sperm injection were enrolled in the study. Serum and follicular RESOLVIN E1 at day of oocyte pickup were measured using ELISA technique. Results: The current study shows significantly lower gonadotropins stimulation dose needed for PCOS females (p <0.001). It also revealed no significant correlations between total gonadotropins dose with both serum and follicular fluids resolvin E1, while there were insignificant negative correlations between serum and follicular fluids resolvin E1 with patients’ ages and body mass indices among PCOS females. Conclusions: There is no correlation between the serum and follicular RvE1 levels in PCOS infertile females.
Identification of Virulence Factor and Phylogenetic Study of Pseudomonas aeruginosa Isolated from Fish Product in Iraq using Molecular Techniques
Authors: Hassan Ban Ali , Saeed Asseel Abdulridha 
Published: October 2024

Pseudomonas aeruginosa is a pathogen bacterium that may cause infection and is commonly found in fish, plants, animals, soil, and water. The abundance of fish and seafood contributes to the seafood sector's economic importance. Several nations rely on the abundance of fish and seafood to support their economies. The objective of this study is to isolate P. aeruginosa and investigate its phylogenic similarity and sequencing to that of referred isolates taken from fresh fish (Cyprinus carpio) and marine (Hammour). One hundred and twenty raw fish samples were gathered from the local marketplaces in Al-Diwaniya City. The isolates of pseudomonas aeruginosa were grown on selective agar, such as chrome-genic pseudomonas agar and cetrimide agar, then identified using microbiology. and biochemical testing. According to the findings the result of PCR detection 16SrRNA gene (21.6%), Las B (5.4%),Oprl gene (4.6%). Furthermore, a phylogenic tree was established to identify the genetic proximity of different species of the eight isolate gene sequencings, the following GenBank accession numbers were determined and submitted: PP534998, PP534999, PP535000, PP53501, PP535002, PP535003, PP535004, and PP535006. The results showed that the isolation rate of P. aeruginosa in local carp was (28%) higher than the rate of isolates from marine fish (9%) when employing PCR. P. aeruginosa isolates exhibited high similarity (96%) for strains isolated from the United States, followed by (88%) for strains isolated from Iraq, and a lower similarity percentage (55%) with other strains recovered from the United States. In conclusion, the PCR is a reliable tool for molecularly detecting Pseudomonas aeruginosa that infected both local carp.
Synergistic Activity of Antibiotics and Bio Active Plant Extract: Astudy Against Mdr Gram Negative Bacteria in Kirkuk City
Authors: Ali Tina Artam , Ali Fawwaz Fadhil , Mohammed Lezan Medhat 
Published: October 2024

Increasing multidrug resistance (MDR) is becoming a problematic issue worldwide. Finding alternatives to cope with this rising problem is becoming crucial for community healthcare. The present study aimed to investigate the antibacterial activityCopper oxide nanoparticles (CuONPs) synthesised using hawthorn fruit extract against different MDR gram-negative bacteria isolates. CuoNPs were synthesized from Fresh hawthorn fruits (Crataegus). The biosynthesized copper oxide nanoparticles were Characterization of the synthesised nanoparticles was performed using UV-visible spectroscopy, Scanning Electron Microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), and X-ray diffraction (XRD) to confirm CuONP production and assess their properties. Antibacterial activity was determined by disc diffusion and the healthy diffusion method. The considerable inhibitory action of hawthorn fruit extract was observed in gram-negative bacteria isolates. Also, the green synthesised CuoNPs demonstrated remarkable antibacterial activity against two human pathogenic bacteria when combined with commercially available antibiotics. The current study suggested that CuoNPs have become an essential approach for nanobiotechnology applications in the development of antibacterial treatments for different bacterial infections, particularly for non-treatable antibiotic resistance pathogen.
Calotropis Procera Triggered Biochemical and Molecular Alterations In Breast Cancer Caused By DMBA In Female Albino Rats
Authors: Alrheam Ali I. Abd , Msolly Awatef A. , Alshehri Zafer S. , Alhajlah Sharif H. , Alshehri Faez F. , Basha Manal I. , Almotiri Alhomidi , Saleem Ali. S. A. , Elneam Ahmed IbrahimAbd 
Published: October 2024

Objectives: To investigate the in vivo anticancer effect of Calotropis procera on breast cancer induced in female albino rats with 7,12-dimethyl benz(a) anthracene (DMBA).
Materials and study design: Fresh leaves of C. procera were obtained from 20 plant specimens collected from various regions in the Dawadmi governorate, Riyadh province, KSA (latitude 24.75387 and longitude 46.773686) in August 2022. Three extracts were obtained from C. procera leaves (aqueous, chloroform, and ethanolic extracts). were investigated for their anticancer activity on female albino rats that were classified into five equal groups (n=30): group 1 (control), group 2 (DMBA control), group 3 (DMBA + aqueous extract), group 4 (DMBA + chloroform extract), and group 5 (DMBA + ethanolic extract).
Results: The animals in groups 3, 4, and 5 treated with C. procera leaf extract exhibited a significant decrease in body weight compared to the animals in group 2 who were only given DMBA, and the survival analysis demonstrated a highly significant disparity between the groups, with the DMBA group displaying a greater incidence of tumors in comparison to the groups treated with C. procera. Biochemical findings indicated a notable variation in the average levels of cholesterol, TG, HDL and LDL between the groups.
Conclusion The results imply that aqueous, chloroform, and ethanolic C. procera leaf extracts may have preventive properties against tumor initiation and promotion.
Correlation of Immunological Variables of Interleukin-17 and Heat Shock Protein-70 In Ethnic Women with Polycystic Ovary Syndrome
Authors: Abdulla Zahraa HA. , Abbass Sahlah KH. , Mustafa Evan MO. 
Published: October 2024

Background: Polycystic ovary syndrome (PCOS) is a hormonal imbalance resulting from high levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in females, leading to immature eggs, ovarian cysts, irregular menstrual cycles, infertility, excessive facial hair growth, and acne. Objective: This study was conducted to follow up the therapeutic effect on some blood, hormonal, and immune variables of samples consisting of 35 patients with polycystic ovary syndrome (PCOS) from women suffering from infertility and infertility, and who visited Azadi Teaching Hospital and private laboratories in Kirkuk city, their ages ranged between (18 - 40 years). Materials and Methods: Sample collection and follow-up began by observing some clinical signs in addition to verifying the results of ultrasound examinations from early February 2023 to early November 2023. Each patient’s examinations were followed up before treatment and three months after taking the treatment. The results we obtained after three months of treatment were compared with the results of the examinations of the patients in the pre-treatment stage and the control group. The treatment plan was based on modifying the patient's dietary lifestyle by following a healthy diet and giving treatment consisting of oral contraceptives, fertility drugs and the use of sugar-reducing drugs such as Glucophage or Metformin, in addition to nutritional supplements such as antioxidants. Result: The results of the therapeutic effect on the patients' diagnostic clinical signs showed a significant decrease in their percentages after three months of treatment compared to the pre-treatment stage such as (ovulation disorders - menstrual disorders - obesity - hirsutism - acne -). The results of the statistical analysis of the study showed that the therapeutic effect showed a significant difference in the body mass index (BMI) after three months of treatment compared to the pre-treatment stage and the control group. The therapeutic effect of the immune factors for each Hast Shock protein 70 and Interleukin-17 also showed a significant decrease at the level (0.000 > p) respectively after three months of taking the treatment compared to the pre-treatment stage and the control group. It was found that there is a significant positive correlation between the level of Heat Shock Protein 70 and the cellular kinetic IL-17.
Evaluation of Periapical Granuloma and Radicular Cyst Regarding the Age, Gender and The Lesion Size
Authors: Maqtoof Ahmed Hani , Al-Drobie Dr.Ban F. 
Published: October 2024

Background: Apical periodontitis (AP) is a common infectious disease characterized by inflammation and bone destruction in the periapical tissues due to microbial infection in the dental pulp . AP is the most frequent inflammatory lesion related to teeth, distinguished by a direct pathway to the bone marrow without epithelial barriers if the dental pulp becomes necrotic and infected. Materials and methods: Thirty paraffin embedded tissue blocks of radicular neck resected samples of 18 preapical granulomas and 12 radicular cysts were processed histopatholgically. Results: the mean patients’ age was 34.37 ± 2.95 years; fifteen patients were aged bellow 30 years and 15 patients were equal or above 30 years. The mean lesions size was significantly higher among patients with radicular cysts than preapical granuloma (5.07 ± 1.35 vs. 0.94 ± 0.21; p=0.048. granulomas lesions were slightly higher among females in age group 30-39 years ( 25% vs. 10%), and the radicular cysts lesions were higher among females in all age group as compare to male patients Conclusions: Lesions size was significantly higher among patients with radicular cysts than that of preapical granuloma. A peak incidence between the third and fourth decades of life and predominance among female
Histological study of effect of Leishmania donovani on ileums mice
Authors: AL-Bawi Zainab Fadhil Jawad , Al-Morshidy Kassim Abdulla Hamza , Hussian Raflaa SH 
Published: October 2024

Background: Leishmania Donovani Is A Form Of Internal Parasite That Belongs To The Genus Leishmania And Is The Type Of Hemo-Flagellate Kinetoplastid That Causes Leishmaniasis. Objective: The Present Study Investigated The Effects Of Inoculation With L. Donovani On The Morphology Of The Ileum In Mice. Methods: Balb/C Mice Were Intraperitoneally Inoculated With L.Donovani(3 Animals/ 4group). After 1,2,3 Month, The Ilea Were Collected And Histologically Processed. Conclusions: Donovani Is Induced Histological Change In Ileum Section After The First Month Infection.
Attention Deficit Hyperactivity Disorder among Children with Speech Difficulties
Authors: Dahash Ahlam Hayder , Mohammed Saja Hashem 
Published: October 2024

Abstract: Speech sound disorders and attention deficit / hyperactivity disorder are developmental disorders that can significantly impact academic success. The comorbidity of these disorders may substantially add to the difficulties experienced by the child and require a combined treatment approach. Objectives: (1) to assess sociodemographic characteristics of children’s with speech difficulties (2) to assess attention deficit hyperactivity disorder and speech difficulties (3) to identify the relationship between attention deficit hyperactivity disorder and speech difficulties. Methodology: A descriptive cross-sectional study design was carried out in Baghdad Teaching Hospital. A non- probability (purposive) study sample of (300) child, who attended Hearing and Speech Center for the period from 12/April/2023 to 25/January/2024. The Questionnaire which is composed of: Socio-demographic characteristics, scales of behavioral problem, attention deficit hyperactivity disorder. Results: The study results reveal that the children experiencing severe attention deficit hyperactivity disorder and that significant relationship have been reported among speech sound disorder with attention deficit hyperactivity disorder at p-values= 0.046, also indicates that there was significant relationship among childhood apraxia and attention deficit hyperactivity disorder at p-values= 0.007. Conclusion: The children experience severe of attention deficit hyperactivity disorder, the significant relationship has been reported among speech sound disorder with attention deficit hyperactivity disorder, also indicates that there was significant relationship among childhood apraxia and attention deficit hyperactivity disorder.Recommendations: An intervention program to be planned accordingly and areas of deficit will be targeted in therapy. Liaison with parents and school teachers is indicated in order to achieve the child’s maximum potential.
Molecular Study of (Mycoplasma Pneumoniae, Streptococcus Pneumoniae) in Respiratory Infections Patients in Thiqar Province
Authors: Ajed Rehab Abdulhassan , Jarullah Basim Abdulhussein 
Published: October 2024

The high death and hospitalization rates caused by bacterial respiratory infections make them a major worldwide health problem. Acute otitis media, bacterial rhinosinusitis, pharyngotonsillitis, bronchitis, and community-acquired pneumonia are among the common respiratory tract illnesses caused by common bacterial respiratory infections, which include Streptococcus pneumoniae, Mycobacterium tuberculosis, Haemophilus influenzae, Chlamydia pneumoniae, Mycoplasma pneumoniae, and Legionella pneumophila. The study aimed to detect uncultivated bacteria in respiratory infections patients (Mycoplasma pneumoniae) and Streptococcus pneumoniae that caused respiratory infections and determined if it caused this infection. The study included 140 patients (67males and 73 females) who were suffering from respiratory infections, ages ranging from 10-80 years, in a period from 1 September 2023 to 1 February 2024, all of the 140 samples collected from Nasiriyah Teaching Hospital, Center for Chest Diseases and Respiratory Diseases in Nasiriyah, Souq Al-Shuyoukh General Hospital, Alhussein Teaching Hospital, Private Clinics in Shatrah. Specimens included a sputum sample and oropharyngeal swab for direct detecting by polymerase chain reaction (pcr) Diagnosis is based on the presence of the (16s rRNA) gene to detect (Mycoplasma pneumoniae, Streptococcus pneumoniae) patients had with un-cultivated bacteria where 3\140(2.14%) of patients had infection with Mycoplasma pneumoniae and 6\140(4.28%) with Streptococcus pneumoniae. The present study was conducted that the most detected bacterial in female group 6 (75.0%), while in the male group 2 (25.0%), in addition, the most isolated bacteria in female group were both M. pneumoniae 3 (50.0%), and S. pneumoniae 3 (50%),whil in age groups in first group 3, while non-detected bacteria in both fourth and seventh age group 0, fever and headache are the most abundant symptoms patients, followed by myalgia (90.6%), chill (66%), cough (59%), and dyspnea (36.6%).