bluuebunny/crossref_metadata_2025_split huggingface dataset:
Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation
Authors: Moorer Megan C. , Hebert Carla , Tomlinson Ryan E. , Iyer Shama R. , Chason Max , Stains Joseph P. 
Published: January 2017

ABSTRACT
In skeletal tissue, loss or mutation of the gap junction protein connexin 43 (Cx43, also known as GJA1) in cells of the osteoblast lineage leads to a profound cortical bone phenotype and defective tissue remodeling. There is mounting evidence in bone cells that the C-terminus (CT) of Cx43 is a docking platform for signaling effectors and is required for efficient downstream signaling. Here, we examined this function, using a mouse model of Cx43 CT-truncation (Gja1 K258Stop). Relative to Gja1+/− controls, male Gja1−/K258Stop mice have a cortical bone phenotype that is remarkably similar to those reported for deletion of the entire Cx43 gene in osteoblasts. Furthermore, we show that the Cx43 CT binds several signaling proteins that are required for optimal osteoblast function, including PKCδ, ERK1 and ERK2 (ERK1/2, also known as MAPK3 and MAPK1, respectively) and β-catenin. Deletion of the Cx43 CT domain affects these signaling cascades, impacting osteoblast proliferation, differentiation, and collagen processing and organization. These data imply that, at least in bone, Cx43 gap junctions not only exchange signals, but also recruit the appropriate effector molecules to the Cx43 CT in order to efficiently activate signaling cascades that affect cell function and bone acquisition.
Predictors of mortality following conservatively managed fractures of the odontoid in elderly patients
Authors: Bajada S. , Ved A. , Dudhniwala A. G. , Ahuja S. 
Published: January 2017

Aims Rates of mortality as high as 25% to 30% have been described following fractures of the odontoid in the elderly population. The aim of this study was to examine whether easily identifiable variables present on admission are associated with mortality. Patients and Methods A consecutive series of 83 elderly patients with a fracture of the odontoid following a low-impact injury was identified retrospectively. Data that were collected included demographics, past medical history and the results of blood tests on admission. Radiological investigations were used to assess the Anderson and D’Alonzo classification and displacement of the fracture. The mean age was 82.9 years (65 to 101). Most patients (66; 79.5%) had a type 2 fracture. An associated neurological deficit was present in 11 (13.3%). All were treated conservatively; 80 (96.4%) with a hard collar and three (3.6%) with halo vest immobilisation. Results The rate of mortality was 16% (13 patients) at 30 days and 24% (20 patients) at one year after injury. A low serum level of haemoglobin and the presence of a neurological deficit on admission were independent predicators of mortality at 30 days on binary logistic regression analysis. A, low level of haemoglobin, admission from an institution, a neurological deficit and type 3 fractures were independent predictors of mortality at one year. Conclusion We suggest that these easily identifiable predictors present on admission can be used to identify patients at high risk and guide management by a multidisciplinary team. Cite this article: Bone Joint J 2017;99-B:116–21.
Minimally invasive periacetabular osteotomy using a modified Smith-Petersen approach
Authors: Khan O. H. , Malviya A. , Subramanian P. , Agolley D. , Witt J. D. 
Published: January 2017

AimsPeriacetabular osteotomy is an effective way of treating symptomatic hip dysplasia. We describe a new minimally invasive technique using a modification of the Smith-Peterson approach. We performed a prospective, longitudinal cohort study to assess for any compromise in acetabular correction when using this approach, and to see if the procedure would have a higher complication rate than that quoted in the literature for other approaches. We also assessed for any improvement in functional outcome.Patients and MethodsFrom 168 consecutive patients (189 hips) who underwent acetabular correction between March 2010 and March 2013 we excluded those who had undergone previous pelvic surgery for DDH and those being treated for acetabular retroversion. The remaining 151 patients (15 men, 136 women) (166 hips) had a mean age of 32 years (15 to 56) and the mean duration of follow-up was 2.8 years (1.2 to 4.5). In all 90% of cases were Tönnis grade 0 or 1. Functional outcomes were assessed using the Non Arthritic Hip Score (NAHS), University of California, Los Angeles (UCLA) and Tegner activity scores.ResultsThe mean pre-operative lateral centre-edge angle was 14.2° (-5° to 30°) and the mean acetabular index was 18.4° (4° to 40°). Post-operatively these were 31° (18° to 46°) and 3° (-7° to 29°), respectively, a significant improvement in both (p < 0.001). Allogenic blood transfusion was required in two patients (1.2%). There were no major nerve or vascular complications, and no wound infections. At the time of last follow-up, we noted a significant improvement in functional outcome scores: UCLA improved by 2.31 points, Tegner improved by 1.08 points, and the NAHS improved by 25.4 points (p < 0.001 for each). Hypermobility and longer duration of surgery were significant negative predictors for a good post-operative UCLA score, while residual retroversion was a positive predictor of post-operative UCLA score.ConclusionWe have found this approach to be safe and effective, facilitating early recovery from surgery. Cite this article: Bone Joint J 2017;99-B:22–8.
Functional outcomes of conservatively managed acute ruptures of the Achilles tendon
Authors: Lawrence J. E. , Nasr P. , Fountain D. M. , Berman L. , Robinson A. H. N. 
Published: January 2017

Aims This prospective cohort study aims to determine if the size of the tendon gap following acute rupture of the Achilles tendon shows an association with the functional outcome following non-operative treatment. Patients and Methods All patients presenting within two weeks of an acute unilateral rupture of the Achilles tendon between July 2012 and July 2015 were considered for the study. In total, 38 patients (nine female, 29 male, mean age 52 years; 29 to 78) completed the study. Dynamic ultrasound examination was performed to confirm the diagnosis and measure the gap between ruptured tendon ends. Outcome was assessed using dynamometric testing of plantarflexion and the Achilles tendon Total Rupture score (ATRS) six months after the completion of a rehabilitation programme. Results Patients with a gap ≥ 10 mm with the ankle in the neutral position had significantly greater peak torque deficit than those with gaps < 10 mm (mean 23.3%; 7% to 52% vs 14.3%; 0% to 47%, p = 0.023). However, there was no difference in ATRS between the two groups (mean score 87.2; 74 to 100 vs 87.4; 68 to 97, p = 0.467). There was no significant correlation between gap size and torque deficit (τ = 0.103), suggesting a non-linear relationship. There was also no significant correlation between ATRS and peak torque deficit (τ = -0.305). Conclusion This is the first study to identify an association between tendon gap and functional outcome in acute rupture of the Achilles tendon. We have identified 10 mm as a gap size at which deficits in plantarflexion strength become significantly greater, however, the precise relationship between gap size and plantarflexion strength remains unclear. Large, multicentre studies will be needed to clarify this relationship and identify population subgroups in whom deficits in peak torque are reflected in patient-reported outcome measures. Cite this article: Bone Joint J 2017;99-B:87–93.
Detection of mercury by a new sensor based CPE modified with extract of takaout plant
Authors: Ait sidi mou Abdelaziz , Ouarzane Aicha , El Rhazi Mama 
Published: January 2017

A new carbon paste electrode (CPE) modified with extractÂ takaoutÂ was developed for the determination of mercury using square wave voltammetry (SWV).Â Compared with carbon paste electrode, the anodic peak current had a significant increase at the modified electrode. Under the optimized conditions (amount of modifier 3%, 0.1 M acetate buffer pH 2, accumulation potential -0.6 V, accumulation time 300 s, resting time 10 s, frequency 25 Hz, pulse amplitude 0.050 V, step height 2 mV), a linear response was obtained in the concentration range from 3.1 to 11 ÂµM Hg(II) and the detection limit was 0.42 ÂµM. The results indicate that this electrode is sensitive and effective for determination of Hg2+Â in the tap water sample.
Chemical composition, antioxidant potential and phenolic profile of oil mill waste water from Tunisian olive varieties (Chetoui and Chemlali)
Authors: Khemakhem Sellami Maissa , Khemakhem Ibtihel , Mkadmini Khaoula , Bouzouita Nabiha 
Published: January 2017

Oil mill waste water (OMWW) is of great interest due to the presence of valuable resources such as biophenols that can be recovered as food additives and pharmaceuticals. The aim of this study is to investigate the variation of physicochemical composition of OMWW from Chetoui and Chemlali varieties, to evaluate phenolic composition, antioxidant potential and phenolic profile of OMWW extracts under native and acidified conditions. Liquid-liquid extraction was performed for the extraction of polyphenols. Antioxidant activity was investigated by DPPHâ€¢, ABTSâ€¢+ and FRAP tests. Phenolic compounds content was determined by HPLC-DAD method. OMWW from Chetoui variety has been shown to contain an important amount of K, Ca and Na whereas Chemlali cultivar was rich in Mg. Phenolic extract from Chetoui fruit (COCt) has beenÂ shown to contain the highest amount of polyphenols (2.48 Â± 0.21 g L-1) as well as an appreciable content of flavonoids (9.39 Â± 0.32 g L-1). However, phenolic extract from Chemlali fruit (COCm) has been shown to have the highest content of proanthocyanidins (0.39 Â± 0.00 g L-1). Acidification treatment improved polyphenol recovery of extracts from both varieties. COCt was more active using DPPH (EC50 of 7.5 mg L-1) and FRAP tests. However, COCt and COCm exhibited the same activity using ABTS test. In general, acidification treatment decreased antioxidant activity of extracts. COCt has been shown to contain higher amount of hydroxytyrosol when compared to COCm (157.16 Â± 0.820 and 23.440 Â± 0.440 mg g-1 D.W. of extract, respectively) as revealed by HPLC-DAD analysis.Â
Direct use of mineral fertilizers MAP, DAP, and TSP as heterogeneous catalysts in organic reactions
Authors: Bahammou Imane , Esaady Ayoub , Boukhris Said , Ghailane Rachida , Habbadi Nouzha , Hassikou Amina , Souizi Abdelaziz 
Published: January 2017

In this paper, we reported the first use of phosphate fertilizers (MAP, DAP, and TSP) as heterogeneous catalysts for organic reactions.Â Their catalytic activities were investigated in the first time in Knoevenagel condensation of various aromatic aldehydes with malononitrile at room temperature.Â These minerals phosphate showed high catalytic activities and ability to be recovering and reusing without a significant loss in their catalytic activities.Â In order to reach the optimal reaction conditions for Knoevenagel condensation, we carried out a kinetic study of the effect of reaction time, the effect of solvent, the amount of catalysts and the variation of the range of the particles size the more active.Â The best conditions were obtained by the use of these fertilizers (MAP, DAP, and TSP) in their commercial status, simply crashed in powder, without any purification, using ethanol as solvent.Â These phosphate fertilizers prove to be very promising and effective heterogeneous catalysts for the condensation of Knoevenagel.
Synthesis, Characterization, Aggregation behaviors, Antioxidant and Anti-inflammatory activities of Unmetalled and metallophthalocyanines bearing 2(3,4-dimethoxyphenyl)ethanol and 4-Hydroxybenzaldehyde groups
Authors: Sulaiman Abduallah 
Published: January 2017

Novel metallophthalocyanines (M: Co, Cu, Ni) containing 2(2-methoxyphenyl)ethanol and 3-Hydroxybenzaldehyde groupsÂ were synthesized and characterized.The structures were confirmed by IR, UV/vis, 1H NMR, 13C NMR, mass spectroscopy Â and elemental analysis. The aggregation behavior of these compounds was investigated in DMSO.Â In addition; the compounds 4-9 were investigated for anti-oxidant activities by super oxide radical; DPPH (2,2-Diphenyl-1-picrylhydrazyl); and hydroxyl radical scavenging assays; in which most of themÂ displayed significant antioxidant activities. Furthermore; compounds 4-9Â Â were evaluated for anti-inflammatory activity by indirect hemolytic and lipoxygenase inhibition assays and revealed good activity.
DIVERSITY OF PLANTS USED FOR PLAITED CRAFTS BY THE DAYAK IBAN-DÉSA IN KABUPATEN SINTANG, KALIMANTAN BARAT, INDONESIA
Authors: DEWI ASIH PERWITA , ARIYANTI NUNIK SRI , WALUJO EKO BAROTO 
Published: January 2017

DEWI, A. P., ARIYANTI N. S. & WALUJO, E. B. 2016. Diversity of plants used for plaited crafts by the Dayak Iban-Désa in Kabupaten Sintang, Kalimantan Barat. Reinwardtia 15(2): 67 – 79. — Many plants are used for making plaited crafts such as basketry and woven mats by the Dayak Iban-Désa, a sub-tribe of the Dayak in Kalimantan Barat, Indonesia. The Dayak Iban-Désa gather the craft materials mostly from the plants in the forest. However, the habitats of these plants are being threatened by deforestation. The diversity of plants used for crafts is here documented. This study recorded the scientific names of plant species used for the craft plaiting, and observed abundance of plants used for craft. Information about the plants used were gathered using non-structural interview and focus group discussion (FGD) with the informants and participants. The abundance of plaited plants was observed in 46 plots of 10 × 10 m2 plots by participative ecological method. Nineteen plants species were used as plaited material, belonging to four families: Arecaceae, Poaceae, Pandanaceae and Zingiberaceae. Two species of rattan (Calamus sp. and Plectocomiopsis wrayi Becc.) have the highest Index Cultural Significance (ICS) value. Those species were considered as the most valuable plant materials because of the quality of fiber, intensity on harvesting, and the resulting quality of plaited craft products. However, the demand for high quality products is not always supported by the availability of plant materials in the forest. Therefore, the cultural significance of plants (the ICS values) and their availability should be considered when determining the conservation strategy for each of these species.
The effects of ultraviolet and visible light on common furs: Color changes, photooxidation and the use of Tinuvin 292 as a photoprotectant
Authors: Rogge Corina E. , Shullman Anya 
Published: January 2017

Abstract
In order to determine the light sensitivities of commonly encountered furs, 17 furs from 12 species were exposed to 1.97 Mlx hours of light from a xenon arc lamp, filtered either to simulate window-filtered daylight or to remove all ultraviolet (UV) radiation. Comparison with coexposed Blue Wools showed that most samples were relatively lightfast (Blue Wool 5 or better), with darker specimens being more lightfast. Examination of the Commission internationale de l'éclairage (CIE) L*a*b* values revealed fading but also other changes: some furs darkened, and other experienced changes in b* values. Removal of UV radiation prevented darkening and usually decreased the magnitude of ΔE76 but did not prevent color changes, and one species exhibited greater change under visible light. Changes in color were accompanied by photooxidation of the keratin of all species as assessed by attenuated total reflectance infrared spectroscopy; the extent of photooxidation was decreased by filtering out UV radiation. Pre-exposure treatment with a spray application of a 1% solution of Tinuvin 292, a hindered amine light stabilizer, offered some protection against both UV and visible light-induced changes. Tinuvin 292 pre-exposure also helped prevent keratin photooxidation and light-induced mechanical damage and thus may be an appropriate preventative treatment when light exposure is unavoidable.
Cleaning protocol for mercuric chloride–contaminated herbarium cabinets at the Smithsonian Museum Support Center
Authors: Fallon Doug , Peters Melinda , Hunt Michael , Koehler Kirsten 
Published: January 2017

Abstract
Mercuric chloride has been used to control insect and fungal infestations in natural history collections for the past two centuries. Due to health concerns, its use was discontinued in the mid-1980s, but specimens treated with mercuric chloride are commonly found in modern collections and present a hazard to collection staff and researchers. Cabinets used to store mercuric chloride–treated specimens also become contaminated with the substance and represent a source of exposure even after specimens are removed. A team at the US National Herbarium, in coordination with the Smithsonian’s Office of Safety, Health and Environmental Management, developed a protocol to clean herbarium cabinets that were contaminated with mercuric chloride. Cabinets were cleaned with 70% ethanol and laboratory wipes, and effectiveness was measured using a portable mercury vapor analyzer and surface wipe sampling. Cleaning with ethanol was found to be more effective than just removing treated specimens, but the differences in reduction of airborne and surface mercury concentrations were not statistically significant. This study provides important insight and guidance for museums seeking to eliminate legacy mercuric chloride contamination from their herbarium cabinets.
Effect of tennis education on problem solving skills in university students<p>Tenis eğitiminin üniversite öğrencilerinin problem çözme becerisi üzerine etkisi
Authors: Vatansever Serife , Özen Güçlü 
Published: January 2017

This study has been carried out with the aim of analyzing and comparing problem solving skills of the students taking or not taking tennis education. Total 80 university students, 40 of whom taking tennis education and 40 of whom not taking these education have participated on the basis of volunteering. This research was conducted in an experimental model. In this study, Problem Solving Inventory adapted into Turkish language by Şahin, Şahin and Heppner (1993) and developed by Heppner and Peterson (1982) has been used. While the trail group participated in a tennis training program of 3 days a week, 2 hours a day and a total of 3 months, the control group continued their normal life without participating in any regular work.Statistical findings have been obtained by means of SPSS 20.0 packaged software. The Independent-t test was applied to examine the difference between the experimental and control groups and the effect of the gender independent variable. And for calculating the difference of pre-test and posttest, Test of Paired Sample was applied According to the parameter of problem solving skill, there was a significant difference between value of the pre-test and value of the post-test on experimental group (<0,05), pbut There was no significant difference between pre-test and post-test values depending on gender variable (>0,05). As a result, it is thought that exercises have a positive change on problem solving skills on the students who taking tennis education. ÖzetBu çalışma tenis eğitimi alan ve almayan öğrencilerin, problem çözme becerilerini inceleme ve karşılaştırma amacı ile yapılmıştır. Çalışmaya tenis eğitimi alan 40 öğrenci ile bu eğitimi almayan 40 öğrenci olmak üzere toplam 80 öğrenci gönüllü olarak katılmıştır. Araştırma deneme modelinde tasarlanmıştır. Çalışmada, Hepner ve Peterson (1982) tarafından geliştirilen, Türkçe’ye uyarlaması ise Şahin, Şahin ve Heppner (1993) tarafından yapılan Problem Çözme Envanteri kullanılmıştır. Deneme grubu haftada 3 gün, günde 2 saat ve toplamda 3 aylık bir tenis eğitimi programına katılırken kontrol grubu herhangi bir düzenli çalışmaya katılmadan normal yaşamlarına devam etmiştir. Verilerin değerlendirilmesinde ve hesaplanmış değerlerin bulunmasında SPSS 20.0 istatistik paket program kullanılmıştır. Deneme ve kontrol grupları arasındaki fark ve cinsiyet bağımsız değişkeninin etkisinin incelenmesi için Bağımsız-t testi yapılmıştır. Ön test-son test arasındaki farklılığın tespiti için ise, Bağımlı-t testi yapılmıştır. Araştırmada, problem çözme becerisi değişkenine göre, deney grubu ön test-son test değerleri arasında anlamlı farklılık bulunmuş (p<0,05), cinsiyet değişkenine bağlı olarak ön test-son test değerleri arasında anlamlı farklılık bulunamamıştır p>0,05). Sonuç olarak, tenis eğitimi alan öğrencilerde problem çözme becerileri egzersize bağlı olumlu yönde değişiklik gösterdiği düşünülmektedir.
Introduction: From Comparative Arts to Interart Studies
Authors: Fischer-Lichte Erika 
Published: January 2017

AbstractThe essays assembled in this volume were initially presented at the concluding conference of the International Doctoral School “InterArt Studies” held at the Freie Universität Berlin from June 25-27, 2015. The school bore the label “international” not just because its students hailed from five different continents. Rather, it was called that because it was born out of the collaboration with the Copenhagen Doctoral School in Cultural Studies, Literature and the Arts, later joined by the Doctoral School of Goldsmiths College, London, and the Graduate School of Arts and Sciences at Columbia University, New York. During these nine years (2006-2015) of research, it was generously funded by the German Research Council.
Is Brazil a Postcolonial Country?
Authors: Iñigo Clavo María 
Published: January 2017

AbstractThe starting point of this essay is the text written by Pierre Bourdieu and Loïc Wacquant entitled “The Cunning of the Imperialist Reason,” in which they discuss the pertinence of transferring concepts regarding race from the American context to the Brazilian context. The authors maintain that this transfer is a ‘false friend’ because the same words are used to signify different things. In this article, I argue that certain uses of postcolonial theory in Brazil might also function as ‘false friends,’ particularly in the use of complex notions of Mestizaje within the art world. The key point of departure for this essay is the following contradiction: abroad, Brazil attracts a great deal of international interest due to its postcolonial condition, and the power of its discourses of racial hybridity through concepts such as cultural anthropophagy which challenge eurocentric paradigms. But, internally, postcolonial studies have attracted little or no interest, especially in academic circles. Why? We will use the exhibition Mestizo Histories (2015) as a case study for this purpose.