bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relation between residual stress, interfacial structure and the joint property in the SiO2f/SiO2-Nb joints
Authors: Ma Qiang , Li Zhuo Ran , Yang Lai Shan , Lin Jing Huang , Ba Jin , Wang Ze Yu , Qi Jun Lei , Feng Ji Cai 
Published: June 2017

AbstractIn order to achieve a high-quality joint between SiO2f/SiO2 and metals, it is necessary to address the poor wettability of SiO2f/SiO2 and the high residual stress in SiO2f/SiO2-Nb joint. Here, we simultaneously realize good wettability and low residual stress in SiO2f/SiO2-Nb joint by combined method of HF etching treatment and Finite Element Analysis (FEA). After etching treatment, the wettability of E-SiO2f/SiO2 was improved, and the residual stress in the joint was decreased. In order to better control the quality of joints, efforts were made to understand the relationship between surface structure of E-SiO2f/SiO2 and residual stress in joint using FEA. Based on the direction of FEA results, a relationship between residual stress, surface structure and joint property in the brazed joints were investigated by experiments. As well the FEA and the brazing test results both realized the high-quality joint of E-SiO2f/SiO2-Nb and the shear strength of the joint reached 61.9 MPa.
Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats
Authors: Yan Jingyu , Xie Guoxiang , Liang Chungeng , Hu Yiyang , Zhao Aihua , Huang Fengjie , Hu Ping , Liu Ping , Jia Wei , Wang Xiaoning 
Published: June 2017

AbstractCholestasis is a clinical disorder defined as an impairment of bile flow, and that leads to toxic bile acid (BA) accumulation in hepatocytes. Here, we investigated the hepatoprotective effect of Yinchenhaotang (YCHT), a well-known formulae for the treatment of jaundice and liver disorders, against the cholestasis using the α-naphthylisothiocyanate (ANIT)-induced cholestasis in male Wistar rats. ANIT feeding induced significant cholestasis with substantially increased intrahepatic retention of hydrophobic BAs. The dynamic changes of serum and liver BAs indicated that YCHT was able to attenuate ANIT-induced BA perturbation, which is consistent with the histopathological findings that YCHT significantly decreased the liver damage. YCHT treatment substantially reduced serum alanine aminotransferase (ALT), alkaline phosphatase (AST), total bilirubin (TBIL) and direct bilirubin (DBIL) with minimal bile duct damage in the ANIT treated rats. Elevated mRNA expression of liver IL-6, IL-17A, IL-17F, TGF-β1, α-SMA, TGR5, NTCP, OATP1a1, and ileum ASBT and decreased liver IL-10, FXR, CAR, VDR, BSEP, MRP2, MRP3, MRP4 was also observed in ANIT-induced cholestasis but were attenuated or normalized by YCHT. Our results demonstrated that the BA profiles were significantly altered with ANIT intervention and YCHT possesses the hepatoprotective potential against cholestatic liver injury induced by hepatotoxin such as ANIT.
Phylogenetic constrains on Polyporus umbellatus-Armillaria associations
Authors: Xing Xiaoke , Men Jinxin , Guo Shunxing 
Published: June 2017

AbstractIt has been well established that some Armillaria species are symbionts of Polyporus umbellatus, However, little is known about the evolutionary history of P. umbellatus-Armillaria associations. In this research, we used an analysis based on the strength of the phylogenetic signal to investigate P. umbellatus-Armillaria associations in 57 sclerotial samples across 11 provinces of China. We isolated Armillaria strains from the invasion cavity inside the sclerotia of P. umbellatus and then phylogenetically analyzed these Armillaria isolates. We also tested the effect of P. umbellatus and Armillaria phylogenies on the P. umbellatus-Armillaria associations. We isolated forty-seven Armillaria strains from 26 P. umbellatus sclerotial samples. All Armillaria isolates were classified into the 5 phylogenetic lineages found in China except for one singleton. Among the 5 phylogenetic lineages, one lineage (lineage 8) was recognized by delimitation of an uncertain phylogenetic lineage in previous study. Results of simple Mantel test implied that phylogenetically related P. umbellatus populations tend to interact with phylogenetically related Armillaria species. Phylogenetic network analyses revealed that the interaction between P. umbellatus and Armillaria is significantly influenced by the phylogenetic relationships between the Armillaria species.
Fabrication of nitrogen-doped nano-onions and their electrocatalytic activity toward the oxygen reduction reaction
Authors: Choi E. Y. , Kim C. K. 
Published: June 2017

AbstractNitrogen-doped nano-onions (NNO) were prepared as electrocatalytic materials for the oxygen reduction reaction (ORR). The nano-onions (NO), spherical graphitic material particles, were prepared by pyrolysis of nanodiamonds (ND). Oxidized NO (ONO) was prepared from NO by a modified Hummers’ method, and this was mixed with urea, followed by pyrolysis, resulting in the formation of NNO. The nitrogen content and molar ratio of nitrogen-containing groups in the NNOs were varied by controlling the oxygen content of ONO to explore the effect of nitrogen content on the ORR activity. The formation of NO was confirmed by Raman spectroscopy, X-ray diffraction analysis, and high-resolution transmission electron microscopy. X-ray photoelectron spectroscopy analyses were conducted to confirm the formation of the NNO and the structures of the nitrogen-containing groups in the NNOs. The ORR activities of the NNOs were investigated using a rotating disk electrode. The NNOs showed a higher onset potential than that of NO, and the ORR activity of the NNO could be improved by increasing the number of active sites (nitrogen-containing groups) in the NNO. In addition, the NNO exhibited better long-term stability and resistance toward methanol crossover in the ORR than the platinum-based catalysts.
Cylindrical optimal rearrangement problem leading to a new type obstacle problem
Authors: Mikayelyan Hayk 
Published: June 2017

An optimal rearrangement problem in a cylindrical domainΩ=D× (0, 1) is considered, under the constraint that the force function does not depend on thexnvariable of the cylindrical axis. This leads to a new type of obstacle problem in the cylindrical domain Δu(x′,xn) =χ{v>0}(x′) +χ{v=0}(x′) [∂νu(x′,0) +∂νu(x′, 1)]arising from minimization of the functional ∫Ω½;|∇u(x)|2+χ{v>0}(x′)u(x) dx,wherev(x′) =∫01u(x′,t)dt, and∂νuis the exterior normal derivative ofuat the boundary. Several existence and regularity results are proven and it is shown that the comparison principle does not hold for minimizers.
The Kaleidoscope of Plant Prescriptions: A Case of Teucrium Marum
Authors: Maher Patricia 
Published: June 2017

AbstractHealing unfolds in a process and a plant prescription may not be the first remedy. This article describes a case of a man with gout, a successful environmental lawyer who with the help of homeopathy manifests his artistic side. Moving from snake remedies to a nosode and finally to a plant, the patient undergoes a delicate and inscrutable process of self-transformation.
Vacuum-Assisted Closure Therapy for the Treatment of Poststernotomy Wound Dehiscence in Neonates and Infants
Authors: Carrozzini Massimiliano , Vida Vladimiro , Stellin Giovanni , Padalino Massimo 
Published: June 2017

AbstractWe sought to analyze effectiveness and results of a vacuum-assisted closure system for the treatment of sternal wound dehiscence in newborns and children after cardiac surgery in our institution. Six patients with poststernotomy wound problems (large defects of epithelialization or mediastinitis) were treated with a vacuum-assisted closure (VAC) therapy. Median age was 5 months (range: 1–144); VAC therapy was started with negative pressure −75 mm Hg, continuously. All children achieved healing of the sternal wound and a subsequent closure after a median length of treatment of 8.3 days (range: 4–14). In conclusion, VAC therapy with high negative pressure is safe, effective, and is a well-tolerated therapy in pediatric patients with either early- or late poststernotomy wound dehiscence.
Chrysin Alters microRNAs Expression Levels in Gastric Cancer Cells: Possible Molecular Mechanism
Authors: Mohammadian Farideh , Pilehvar-Soltanahmadi Younes , Alipour Shahriar , Dadashpour Mehdi , Zarghami Nosratollah 
Published: June 2017

Abstract
Background Gastric carcinoma still remains the second most common cause of cancer mortality in the world. Chrysin, as a flavone, has showed cancer chemopreventive activity. The cellular and molecular mechanisms of chrysin in cancer cells have not been fully understood.
Objective In this study, we investigate expression levels of let-7a, miR-9, mir-18a, miR-21, miR-22, miR-34a, miR-126 and mir-221 to describe the anti-cancer effects of chrysin.
Materials and Methods The cytotoxic effects of chrysin were assessed using MTT assay. The effect of chrysin on the microRNAs expression was determined by qRT-PCR.
Results The MTT results for different concentrations of chrysin at different times on the Gastric carcinoma cells showed that IC50 for chrysin was 68.24 µM after 24 h of treatment. Expression analysis identified that miR-18, miR-21 and miR-221 were down regulated whereas let-7a, miR-9, miR-22, miR-34a and miR-126 were up regulated in Gastric carcinoma cell line (p<0.05).
Conclusion Treatment with chrysin can alter the miRNAs expression and these findings might be an explanation for molecular mechanism of chrysin effect on gastric cancer.
Die probabilistische Effizienzgrenze: eine Wirtschaftlichkeitsanalyse von Therapieoptionen im Indikationsgebiet Hepatitis C
Authors: Mühlbacher Axel , Sadler Andrew 
Published: June 2017

Zusammenfassung
Hintergrund Das IQWiG entwickelte die Methodik der Effizienzgrenze, um den gesetzlichen Vorgaben über die Bewertung der Wirtschaftlichkeit von Gesundheitstechnologien nachzukommen. Bislang wurden Effizienzgrenzen nur auf Basis einzelner Endpunkte berechnet. Dies widerspricht der Realität eines multidimensionalen Patientennutzens.
Ziel Zielsetzung der Studie war die Operationalisierung eines multidimensionalen Nutzens und die Berechnung einer Effizienzgrenze unter Berücksichtigung der Unsicherheit bei klinischen Effekt- und Präferenzdaten. Die Fallstudie sollte dokumentieren, wie die methodischen Herausforderungen überwunden werden können, um die Effizienzgrenze zur Wirtschaftlichkeitsanalyse und Entscheidungsfindung im Bereich der Hepatitis C sinnvoll zu nutzen.
Methode Die Operationalisierung des Patientennutzes erfolgte über mehrere patientenrelevante Zielkriterien. Für die Aggregation des Gesamtnutzens wurden Präferenzdaten herangezogen. In einer Monte-Carlo-Simulation mit 10000 Zufallsziehungen wurden patientenrelevante Endpunkte mit einer Beta-Verteilung und Präferenzdaten mit einer Normalverteilung berücksichtigt. Der Gesamtnutzen in Relation zu den Kosten informierte über die Angemessenheit der Preise. Die Parameterunsicherheit wurde mithilfe der Preis-Akzeptanz-Kurve und des Netto-Kosten-Vorteils dargestellt.
Ergebnisse Seit Beginn der antiviralen Therapien zur Behandlung von Hepatitis C wurden große Nutzen- bzw. Effizienzsprünge vollzogen. Auf Basis der hier berücksichtigten Effekt- und Präferenzdaten erwiesen sich die interferonfreien Behandlungsoptionen zum derzeitigen Preisniveau als effizient. Die Therapien der neuesten Generation erzielten einen positiven Netto-Kosten-Vorteil.
Schlussfolgerung Die vom IQWiG beschriebene Methodik zur Berechnung der Effizienzgrenze und der Unsicherheit konnte für den Bereich der HCV Therapie praktisch umgesetzt werden. Die Effizienzgrenze, die Preis-Akzeptanz-Kurve und der Netto-Kosten-Vorteil können im Rahmen der Erstattungsentscheidungen bzw. der Preisverhandlungen wesentliche Informationen beisteuern.
Europäische Zusammenarbeit in der Bewertung von Medizinprodukten – ein Schritt zur grenzüberschreitenden Gesundheitsversorgung
Authors: Mayer Julia , Ettinger Sabine , Nachtnebel Anna 
Published: June 2017

Zusammenfassung
Ziel Ziel des Artikels ist die Darstellung rechtlicher Rahmenbedingungen sowie Erfahrungen in der grenzüberschreitenden Zusammenarbeit bei der Bewertung von Medizinprodukten als Grundlage für Erstattungsentscheidungen. Der mögliche Nutzen transnationaler Kooperation für verschiedene Stakeholdergruppen soll erläutert werden.
Methodik Prozesse und Herausforderungen der abgeschlossenen European Network for Health Technology Assessment (EUnetHTA) Joint Action 2 (JA2) werden zusammengefasst und diskutiert. Die dem Artikel zugrunde liegenden Erfahrungen beruhen auf der Erstellung und Evaluierung von insgesamt 6 Rapid Assessments zu Medizinprodukten, welche während der EUnetHTA JA2 in internationaler Kollaboration verfasst und publiziert wurden. Nutzen, Ziele und Chancen der laufenden EUnetHTA Joint Action 3 (JA3) werden dargestellt.
Ergebnisse Herausforderungen in der europäischen Medizinproduktebewertung umfassen die Themenauswahl und den Zeitpunkt der Bewertung, die Intransparenz des Medizinproduktemarkts sowie das Fehlen europäischer Standards zum systematischen Einbeziehen von PatientInnen. Charakteristika wie inkrementelle Veränderungen und Lernkurven machen es notwendig, Medizinprodukte über ihren gesamten Lebenszyklus hinweg zu begleiten. Der Nutzen der europäischen Zusammenarbeit für Stakeholder ist vielfältig: die aufgrund fehlender Evidenz herrschende Unsicherheit zum Zusatznutzen einer Technologie kann durch Early Dialogues reduziert werden; ein europaweit harmonisierter, transparenter Bewertungsprozess steigert die Nachvollziehbarkeit und Qualität der Berichte; die Arbeitsteilung unter den Health Technology Assessment (HTA)-Organisationen ermöglicht eine ressourcenschonende Bewertung einer größeren Anzahl an Technologien; die Patientenbeteiligung gewährleistet die Berücksichtigung patientenrelevanter Endpunkte. Die Wichtigkeit der grenzübergreifenden Zusammenarbeit im Bereich HTA zeigt sich in der Weiterführung des EUnetHTA Projekts, welches die Festigung der internationalen Kollaboration auch nach Auslaufen der EU-Förderungen zum Ziel hat.
Schlussfolgerung Eine nachhaltige transnationale Kooperation in der Bewertung von Medizintechnologien kann die grenzüberschreitende Gesundheitsversorgung und die effiziente Zusammenarbeit der nationalen Gesundheitssysteme sichern. Der Fokus sollte dabei auf einer flächendeckenden Implementierung gemeinsam entwickelter Methoden und Qualitätsstandards liegen. Die europäische Zusammenarbeit kann zu einem konkreten Nutzen für PatientInnen, ÄrztInnen, HTA-Organisationen und nationale EntscheidungsträgerInnen führen.
Complementing Warm-up with Stretching Routines: Effects in Sprint Performance
Authors: Marinho Daniel , Gil Maria , Cardoso Marques Mario , Barbosa Tiago , Neiva Henrique 
Published: June 2017

AbstactThe present study aimed to examine the effects of using static or dynamic stretching added to the common warm-up routine for short sprint distances and to repeated sprint performance. In 3 different sessions, 16 college-age men (n=10) and women (n=6) performed one of 3 warm-ups followed by a 2×60 m dash sprint time trial (5 min of rest) in a counterbalanced design. The control warm-up consisted of 10 min of light-intensity running, and the 2 experimental warm-ups included a static or dynamic stretching routine (5 exercises) in the control warm-up. Performance (time) and physiological variables (tympanic temperature, heart rate) were monitored. In the first 60 m time trial, there were no differences between the 3 warm-ups tested (F=0.21, p=0.73; ηp
2=0.01), as opposed to that observed in the second (F=7.04, p<0.01; ηp
2=0.32). The participants were 1.7% faster after the static stretching warm-up compared with the control warm-up. The sum of the time performed in the 2 sprints emphasizes these results, with better performances after the static stretching warm-up than the control (1%) or dynamic stretching warm-up (0.7%). These results suggest that including a set of static or dynamic stretching exercises may enhance sprinting performance. The better performance in the second trial after the warm-up including static stretching suggests that this type of stretching may positively influence repeated sprint performance (<10 s sprint).
New possibilities for translation
Authors: Cornelio Dawn M. 
Published: June 2017

Abstract
Pioneered by feminist ethicist and psychologist Carol Gilligan in her 1982 work In a Different Voice, care theory rests, according to philosopher Rita Manning, on four key elements: Moral Attention, Sympathetic Understanding, Relationship Awareness, and Harmony. Combined with the notion of voice present in Gilligan’s title, each of these components represents a key portion of the translator-text-author relationship, particularly when translation is seen as negotiation. In this contribution, after examining the notion of translation as negotiation as Eco describes it, I will offer an overview of the psycho-sociological theory of care, with the aim of presenting it as a framework for ethical decision-making in negotiating the act of translation. The importance of translaboration will become evident through the theories of Ricoeur and an emphasis on the cooperative nature of ethically negotiated decisions; i.e., ‘trans’ and its insistence on moving across, beyond, through; and ‘laboration’ and its insistence on the continuing and ongoing process of working.
Project‐based learning in post‐WWII Japanese school curriculum: an analysis via curriculum orientations
Authors: Nomura Kazuyuki 
Published: June 2017

ABSTRACTIn the 2000s, the new national curriculum, dubbed as the ‘yutoricurriculum,’ introduced a new subject for project‐based learning ‘Integrated Study’ as its prominent feature. Comparing curriculum orientations in project‐based learning in three historical periods after the WWII including Integrated Study, this paper aims to offer a genealogy of postwar Japanese school curriculum primarily based on a critical reading of the national curriculum guidelines on project‐based learning, which is emblematic of the extending power of postwar Japan's curriculum authorities. Although Integrated Study was purportedly child‐centered and put emphasis on each child's personal relevance and each school's autonomy, the finding of this study shows that Integrated Study in the yutori curriculum was rather a technology that disciplined schools, teachers, and classroom processes to shape children into morally good and cognitively flexible Japanese nationals. Despite its rhetoric of child‐centeredness and personal relevance, the introduction of Integrated Study as part of the yutori curriculum was ultimately part of the state's move to gain further control over schooling.
Multiple‐joint exercises using elastic resistance bands vs. conventional resistance‐training equipment: A cross‐over study
Authors: Iversen Vegard M. , Mork Paul Jarle , Vasseljen Ottar , Bergquist Ronny , Fimland Marius S. 
Published: June 2017

AbstractPrevious studies indicate that elastic resistance bands (ERB) can be a viable option to conventional resistance‐training equipment (CRE) during single‐joint resistance exercises, but their efficacy has not been established for several commonly used multiple‐joint resistance exercises. Thus, we compared muscular activation levels in four popular multiple‐joint exercises performed with ERB (TheraBand®) vs. CRE (Olympic barbell or cable pulley machines). In a cross‐over design, men and women (n = 29) performed squats, stiff‐legged deadlifts, unilateral rows and lateral pulldown using both modalities. Multilevel mixed‐effects linear regression analyses of main and interaction effects, and subsequent post hoc analyses were used to assess differences between the two resistance‐training modalities. CRE induced higher levels of muscle activation in the prime movers during all exercises (p < .001 for all comparisons), compared to muscle activation levels induced by ERB. The magnitude of the differences was marginal in lateral pulldown and unilateral rows and for the erector spinae during stiff‐legged deadlifts. In squats the quadriceps femoris activations were substantially lower for ERB. The differences between ERB and CRE were mostly observed during the parts of the contractions where the bands were relatively slack, whilst the differences were largely eliminated when the bands became elongated in the end ranges of the movements. We conclude that ERB can be a feasible training modality for lateral pulldowns, unilateral rows and to some extent stiff‐legged deadlifts, but not for the squat exercise.
A Unified Approach to the Thermodynamics and Quantum Scaling Functions of One-Dimensional Strongly Attractive SU(w) Fermi Gases*
Authors: Yu Yi-Cong , Guan Xi-Wen 
Published: June 2017

Abstract
We present a unified derivation of the pressure equation of states, thermodynamics and scaling functions for the one-dimensional (1D) strongly attractive Fermi gases with SU(w) symmetry. These physical quantities provide a rigorous understanding on a universality class of quantum criticality characterized by the critical exponents z = 2 and correlation length exponent ν = 1/2. Such a universality class of quantum criticality can occur when the Fermi sea of one branch of charge bound states starts to fill or becomes gapped at zero temperature. The quantum critical cone can be determined by the double peaks in specific heat, which serve to mark two crossover temperatures fanning out from the critical point. Our method opens to further study on quantum phases and phase transitions in strongly interacting fermions with large SU(w) and non-SU(w) symmetries in one dimension.
Differentiated Care Pathways for Antiretroviral Therapy Monitoring in Malawi: Expanding Viral Load Testing in Setting of Highly Prevalent Resistance
Authors: Rutstein Sarah E , Compliment Kara , Nelson Julie A E , Kamwendo Deborah , Mataya Ronald , Miller William C , Hosseinipour Mina C 
Published: June 2017

Abstract
We quantified resistance to first-line antiretroviral therapy among previously unmonitored patients in Malawi with viremia (≥1000 copies/mL). Ninety-five percent (n = 57/61) harbored nucleoside/tide reverse transcriptase inhibitor/non-nucleoside reverse transcriptase inhibitor resistance; resistance was more common comparing &gt;2 (97%) versus ≤2 years (87%) on therapy. Immediate switch for persons retained in care may improve monitoring efficiency and maximize clinical outcomes.
Product market competition, R&D investment choice, and real earnings management
Authors: Hsiao Hsiao-Fen , Liao Szu-Lang , Su Chi-Wei , Sung Hao-Chang 
Published: June 2017

Purpose
Recent studies in the accounting literature have investigated the economic consequences of R&D capitalization. Discretionary R&D capitalization for target beating can be characterized as a firm signaling private information on its future economic benefits or as opportunistic earnings management. R&D capitalization also has an impact on a firm’s marginal costs and product market competition. The purpose of this paper is to address how firms choose R&D levels for the purpose of meeting or beating their earnings targets and how this influences sequential product market competition.

Design/methodology/approach
The authors study this issue in a stylized game-theoretic model where R&D choices of a firm are not only strategically made but also used to convey proprietary information to its rival. The model provides a rationale for a firm distorting its R&D level to earn more profits and meet its earnings target.

Findings
The equilibrium result indicates that before the realization of common cost shock, a firm can influence the output of its accounting system (i.e. meeting an earnings target) through adjusting its R&D choices. This firm will overinvest in R&D, and this will give an opportunity to create some reserves to be used later to earn a higher profit and reach the earnings target.

Originality/value
This paper contributes to the research on real earnings management in terms of how R&D capitalization affects a firm’s R&D choices by influencing the output of its accounting system through adjusting its R&D choices and the strategic impact of those choices.