bluuebunny/crossref_metadata_2025_split huggingface dataset:
Room temperature and low temperature toughness improvement in SAN/ASA blends by blending with CPE, HNBR, and BR
Authors: Mao Zepeng , Zhang Jun 
Published: June 2017

ABSTRACTStyrene‐acrylonitrile copolymer (SAN)/acrylonitrile‐styrene‐acrylate terpolymer (ASA) blends (75/25, wt/wt) was toughened by blending with impact modifiers including chlorinated polyethylene (CPE), hydrogenated nitrile butadiene rubber (HNBR), and butadiene rubber (BR) and the impact property was tested at four temperatures (–30, −15, 0, and 25 °C). The combination of CPE and HNBR was imported to toughen the SAN/ASA blends, indicating that CPE and HNBR had similar toughening effect at room temperature but HNBR exhibited a better performance at low temperature. When a little HNBR was substituted by BR, the impact strength improved dramatically with the total content of impact modifiers keeping at 30 phr. After 15 phr CPE, 10 phr HNBR and 5 phr BR were employed into blends together, the impact strength reached to a peak of 14 kJ/m2 at −30 °C while the impact strength of the blends individually toughened by 30 phr CPE or 30 phr HNBR was 5 or 12 kJ/m2, respectively. The toughening mechanism showed that the low glass‐transition temperature (–108 °C) of BR and the compatibilization between BR and matrix accounted for the improvement of toughness. Simultaneously, scanning electron microscopy, dynamic mechanical analysis, flexural and tensile properties, heat distortion temperature, and Fourier transform infrared spectroscopy were measured. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45364.
Thermal, mechanical, and rheological properties of graphite‐ and graphene oxide‐filled biodegradable polylactide/poly(ɛ‐caprolactone) blend composites
Authors: Botlhoko Orebotse Joseph , Ramontja James , Ray Suprakas Sinha 
Published: June 2017

ABSTRACTThe effect of graphite (G) and graphene oxide (GO) dispersions on the thermal, mechanical, rheological properties of biodegradable polylactide (PLA)/poly(ɛ‐caprolactone) (PCL) blend composites has been comparatively investigated. Surface morphology analysis indicates that the degree of morphological stability depends on not only the loading of the filler but also enthalpic interaction between the filler surface and the polymer blend. A significant improvement in the elongation at break (43.8%), with well‐balance of modulus and strength characteristics, is observed for the G‐filled (0.25 wt %) blend composite, whereas the GO‐filled (0.05 wt %) ternary composite shows a strong (∼19 °C) improvement in the thermal stability. Furthermore, the dynamic modulus of the blends increased after composite formation; however, the degree of improvement is greater for the G‐filled blend composites. On the basis of the obtained results, we propose a general description of how the morphology and structure of the blend composites are related to the final properties. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci.2017,134, 45373.
A novel Bayesian inference soft sensor for real‐time statistic learning modeling for industrial polypropylene melt index prediction
Authors: Sun Yuanmeng , Wang Yalin , Liu Xinggao , Yang Chunhua , Zhang Zeyin , Gui Weihua , Chen Xu , Zhu Bochao 
Published: June 2017

ABSTRACTA novel real‐time soft sensor based on a sparse Bayesian probabilistic inference framework is proposed for the prediction of melt index in industrial polypropylene process. The Bayesian framework consists of a relevance vector machine for predicting melt index and a particle filtering algorithm for soft sensor optimization. An online correcting strategy is also developed for improving the performance of real‐time melt index prediction. The method takes advantages of the probabilistic inference and using prior statistical knowledge of polymerization process. Developed soft sensors are validated with ten public databases from UCI machine learning repository and real data from industrial polypropylene process. Experimental results indicate the effectiveness of proposed method and show the improvement in both prediction precision and generalization capability compared with the reported models in literatures. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017, 134, 45384.
Metal‐Ion Induced In Situ Ligand Oxidation for Self‐Assembled Clusters: from Bis(5‐(2‐pyridine‐2‐yl)‐1,2,4‐triazole‐3‐yl)methane to Alcohol or Ketone
Authors: Lin Wei‐Quan , Peng Yuan‐Yuan , Tong Lang , Jia Jian‐Hua , Liu Jun‐Liang , Chen Yan‐Cong , Chen Wen‐Bin , Tong Ming‐Liang 
Published: June 2017

AbstractHydrothermal reactions of metal nitrates and ligand bis(5‐(pyridine‐2‐yl)‐1,2,4‐triazol‐3‐yl)methane (H2L1) gave three cluster compounds, {Cr2}, {Zn12} and {Fe8}. Notably, methylene group of H2L1 was in situ oxidized either to hydroxymethylated (L2‐O)3− in the metallo‐ring {Zn12} or to a rigid carbonylated (L3=O)2− in the screw‐type {Fe8}. In light of comparative experimental results, NO3− was deduced to be of a catalytic role in the ligand oxidation. Metal ion could be regarded as an “induced” tool for clusters generation in self‐assembly process.
Die neue Kienlesbergbrücke in Ulm – Herausforderungen der Objektplanung im komplexen Baukontext
Authors: Akkermann Jan , Vieth Heinz‐Josef , Halaczek Bartlomiej 
Published: June 2017

AbstractDie 270 m lange Kienlesbergbrücke ist die Verbindung für die neue Straßenbahnlinie 2 sowie Fußgänger und Radfahrer zwischen der Ulmer Innenstadt und der nordwestlich gelegenen Wissenschaftsstadt. Die Brücke überquert einen dichten Verkehrsknotenpunkt der Deutschen Bahn in unmittelbarer Nähe zum Ulmer Hauptbahnhof, bei dem zeitgleich die Zufahrt zum Portal des Albabstiegtunnels der Neubaustrecke Stuttgart–Ulm realisiert wird. Die komplexen geometrischen und bauzeitlichen Zwangspunkte bedingten eine hochgradig ungleichförmige Bauwerksgestaltung, welcher der Brückenentwurf auch formal im Kontext der historischen Umgebung gerecht wird. Der wellenförmige, im Querschnitt asymmetrische Überbau folgt als orthotrope Platte ausgebildet dem sich aus der Geometrie ergebenden Kraftfluss. Aufgrund Restriktionen im Baufeld wurde der semi‐integrale Stahlüberbau im Längsverschub erstellt.
Carbazole–azine based fluorescence ‘off–on’ sensor for selective detection of Cu2+ and its live cell imaging
Authors: Christopher Leslee Denzil Britto , Karuppannan Sekar , Vengaian Karmegam Muthu , Gandhi Sivaraman , Subramanian Singaravadivel 
Published: June 2017

AbstractA new carbazole–azine based fluorescent sensor was synthesized and characterized. The selectivity of the sensor for Cu2+ over other counter ions in a dimethyl sulfoxide/H2O mixture was shown through enhancement in fluorescence – an off to on transformation. The specificity of the probe towards Cu2+ was evident in ultraviolet/visible, fluorescence, Fourier transform infrared and mass studies. Application of the probe in the cell imaging and cytotoxicity of living cells is illustrated.
Minimally invasive surgery and its impact on 30-day postoperative complications, unplanned readmissions and mortality
Authors: Sood A , Meyer C P , Abdollah F , Sammon J D , Sun M , Lipsitz S R , Hollis M , Weissman J S , Menon M , Trinh Q-D 
Published: June 2017

Abstract

Background
A critical appraisal of the benefits of minimally invasive surgery (MIS) is needed, but is lacking. This study examined the associations between MIS and 30-day postoperative outcomes including complications graded according to the Clavien–Dindo classification, unplanned readmissions, hospital stay and mortality for five common surgical procedures.

Methods
Patients undergoing appendicectomy, colectomy, inguinal hernia repair, hysterectomy and prostatectomy were identified in the American College of Surgeons National Surgical Quality Improvement Program database. Non-parsimonious propensity score methods were used to construct procedure-specific matched-pair cohorts that reduced baseline differences between patients who underwent MIS and those who did not. Bonferroni correction for multiple comparisons was applied and P &lt; 0·006 was considered significant.

Results
Of the 532 287 patients identified, 53·8 per cent underwent MIS. Propensity score matching yielded an overall sample of 327 736 patients (appendicectomy 46 688, colectomy 152 114, inguinal hernia repair 59 066, hysterectomy 59 066, prostatectomy 10 802). Within the procedure-specific matched pairs, MIS was associated with significantly lower odds of Clavien–Dindo grade I–II, III and IV complications (P ≤ 0·004), unplanned readmissions (P &lt; 0·001) and reduced hospital stay (P &lt; 0·001) in four of the five procedures studied, with the exception of inguinal hernia repair. The odds of death were lower in patients undergoing MIS colectomy (P &lt; 0·001), hysterectomy (P = 0·002) and appendicectomy (P = 0·002).

Conclusion
MIS was associated with significantly fewer 30-day postoperative complications, unplanned readmissions and deaths, as well as shorter hospital stay, in patients undergoing colectomy, prostatectomy, hysterectomy or appendicectomy. No benefits were noted for inguinal hernia repair.
One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis
Authors:   SCANDIV Study Group, Schultz J K , Wallon C , Blecic L , Forsmo H M , Folkesson J , Buchwald P , Kørner H , Dahl F A , Øresland T , Yaqub S , Papp A , Ersson U , Zittel T , Fagerström N , Gustafsson D , Dafnis G , Cornelius M , Egenvall M , Nyström P O , Syk I , Vilhjalmsson D , Arbman G , Chabok A , Helgeland M , Bondi J , Husby A , Helander R , Kjos A , Gregussen H , Talabani A J , Tranø G , Nygaard I H , Wiedswang G , Sjo O H , Desserud K F , Norderval S , Gran M V , Pettersen T , Sæther A 
Published: June 2017

Abstract

Background
Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated with similar mortality, less stoma formation but a higher rate of early reintervention. The aim of this study was to compare 1-year outcomes in patients who participated in the randomized Scandinavian Diverticulitis (SCANDIV) trial.

Methods
Between February 2010 and June 2014, patients from 21 hospitals in Norway and Sweden presenting with suspected perforated diverticulitis were enrolled in a multicentre RCT comparing laparoscopic lavage and sigmoid resection. All patients with perforated diverticulitis confirmed during surgery were included in a modified intention-to-treat analysis of 1-year results.

Results
Of 199 enrolled patients, 101 were assigned randomly to laparoscopic lavage and 98 to colonic resection. Perforated diverticulitis was confirmed at the time of surgery in 89 and 83 patients respectively. Within 1 year after surgery, neither severe complications (34 versus 27 per cent; P = 0·323) nor disease-related mortality (12 versus 11 per cent) differed significantly between the lavage and surgery groups. Among the 144 patients with purulent peritonitis, the rate of severe complications (27 per cent (20 of 74) versus 21 per cent (15 of 70) respectively; P = 0·445) and disease-related mortality (8 versus 9 per cent) were similar. Laparoscopic lavage was associated with more deep surgical-site infections (32 versus 13 per cent; P = 0·006) but fewer superficial surgical-site infections (1 versus 17 per cent; P = 0·001). More patients in the lavage group underwent unplanned reoperations (27 versus 10 per cent; P = 0·010). Including stoma reversals, a similar proportion of patients required a secondary operation (28 versus 29 per cent). The stoma rate at 1 year was lower in the lavage group (14 versus 42 per cent in the resection group; P &lt; 0·001); however, the Cleveland Global Quality of Life score did not differ between groups.

Conclusion
The advantages of laparoscopic lavage should be weighed against the risk of secondary intervention (if sepsis is unresolved). Assessment to exclude malignancy (although uncommon) is advised. Registration number: NCT01047462 (http://www.clinicaltrials.gov).
SNAP‐Tag‐Based Subcellular Protein Labeling and Fluorescent Imaging with Naphthalimides
Authors: Wang Chao , Song Xinbo , Xiao Yi 
Published: June 2017

AbstractGenetically encoded technologies provide methods for the specific labeling and imaging of proteins, which is essential to understand the subcellular localization of these proteins and their function. Herein, we employed naphthalimide, an efficient two‐photon fluorophore, to develop O6‐benzylguanine (BG) derivatives for specific labeling of subcellular proteins and fluorescent imaging through the SNAP‐tag. Three naphthalimide–BG derivatives, TNI‐BG, QNI‐BG, and ONI‐BG, were conveniently synthesized through modular “click chemistry” in high yields. All of them showed high labeling efficiency with SNAP‐tag in solution (≈1–2×103 s−1 m−1) and in bacteria. Among them, ONI‐BG showed high specificity to diffused, histone H2B and mitochondria COX8A targeted SNAP‐tag in mammalian cells. The protein‐labeled naphthalimides exhibited high two‐photon absorption cross‐sections, which indicated their potential application in protein‐specific two‐photon fluorescent imaging, such as two‐photon fluorescent lifetime imaging and two‐photon multicolor imaging. Therefore, ONI‐BG is a versatile tool that can be used to track subcellular proteins through multiple fluorescent techniques.
Tuning Sulfur Oxidation States on Thioether‐Bridged Peptide Macrocycles for Modulation of Protein Interactions
Authors: Perell Gabriella T. , Staebell Rachel Lynn , Hairani Mehrdad , Cembran Alessandro , Pomerantz William C. K. 
Published: June 2017

AbstractThioethers, sulfoxides, and sulfonium ions, despite diverse physicochemical properties, all engage in noncovalent interactions with proteins. Thioether‐containing macrocycles are also attracting attention as protein–protein interaction (PPI) inhibitors. Here, we used a model PPI between α‐helical mixed lineage leukemia (MLL) protein and kinase‐inducible domain interacting (KIX) domain to evaluate oxidation effects on sulfurcontaining macrocycle structure, stability, and protein affinity. Desolvation effects from various polarity states were evaluated computationally and experimentally at the side chain, amino acid, and peptide level. Sulfur‐containing side chains spanned polarity ranges between all‐hydrocarbon and lactam bridges for modulating solubility, cellular uptake, and affinity. Helical propensity studies showed that, although oxidized sulfur‐containing side chains could be tolerated, conformational effects were sequence‐dependent. In some cases, proteolytic stability, binding capacity with KIX, and increased helicity were obtained as first steps toward developing PPI inhibitors.
Conjunction of Pyrrole and Amide Moieties: Highly Anion‐Responsive π‐Electronic Molecules Forming Ion‐Free and Ion‐Pairing Assemblies
Authors: Kuno Atsuko , Tohnai Norimitsu , Yasuda Nobuhiro , Maeda Hiromitsu 
Published: June 2017

AbstractDipyrrolyldiketone BF2 complexes with amide units at pyrrole α‐positions were synthesized in modest yields and showed extremely high anion‐binding affinities because of multiple hydrogen‐bonding interactions. The phenyl‐amide‐substituted derivative formed solid‐state chiral helical structures, wherein π planes were oriented parallel to the helical directions. Examination of anion‐binding behavior using 1H NMR spectroscopy combined with theoretical studies suggested fast pyrrole inversions, particularly for the phenyl‐amide‐substituted derivative. The anion complexes behaved as building units of ion‐pairing assemblies in combination with planar and bulky cations.
Silver(I) Clusters with Carba‐closo‐dodecaboranylethynyl Ligands: Synthesis, Structure, and Phosphorescence
Authors: Hailmann Michael , Wolf Natalia , Renner Rebecca , Hupp Benjamin , Steffen Andreas , Finze Maik 
Published: June 2017

AbstractSalts of anionic silver(I) clusters with the carba‐closo‐dodecaboranylethynyl ligand were obtained from {Ag2(12‐C≡C‐closo‐1‐CB11H11)}n, selected pyridines, and [Et4N]Cl or [Ph4P]Br. Salts of octahedral silver(I) clusters [Et4N]2[Ag6(12‐C≡C‐closo‐1‐CB11H11)4(4‐X‐C5H5N)x] were formed with pyridine (X=H, x=8), 4‐methylpyridine (X=Me, x=8), and 4‐cyanopyridine (X=CN, x=10). In contrast, 3,5‐lutidine (3,5‐Me2Py) did not result in salts of dianionic clusters, even in the presence of excess of [Et4N]Cl or [Ph4P]Br; instead salts of monoanionic AgI7 clusters, [Et4N][Ag7(12‐C≡C‐closo‐1‐CB11H11)4(3,5‐Me2Py)9] and [Ph4P][Ag7(12‐C≡C‐closo‐1‐CB11H11)4(3,5‐Me2Py)13] were obtained. The AgI7 cluster is pentagonal bipyramidal in the former, but is an edge‐capped octahedron in the latter. The 4‐methylpyridine and 3,5‐lutidine complexes show green phosphorescence at room temperature. Although argentophilic interactions give rise to sufficient spin–orbit coupling for intersystem crossing S1→Tn and moderate‐to‐high radiative rate constants, time‐resolved measurements indicate that the quantum yields are greatly influenced by the pyridine ligands, which mainly determine the non‐radiative rate constants. In addition, the crystal structures of [Ag16(12‐C≡C‐closo‐1‐CB11H11)8(Py)9.25(CH3CN)2(CH2Cl2)0.75]⋅CH2Cl2, [Ag8(12‐C≡C‐closo‐1‐CB11H11)4(Py)12], [Ag10(12‐C≡C‐closo‐1‐CB11H11)4(4‐MePy)10Br2], [Ag7(12‐C≡C‐closo‐1‐CB11H11)3(4‐tBuPy)11Cl]⋅(4‐tBuPy), and [Ag9(12‐C≡C‐closo‐1‐CB11H11)4(3,5‐Me2Py)11Cl] were elucidated.
A Photo‐Crosslinkable Biotin Derivative of the Phosphoantigen (E)‐4‐Hydroxy‐3‐Methylbut‐2‐Enyl Diphosphate (HMBPP) Activates Vγ9Vδ2 T Cells and Binds to the HMBPP Site of BTN3A1
Authors: Mattarei Andrea , Enzinger Monika , Gu Siyi , Karunakaran Mohindar Murugesh , Kimmel Brigitte , Berner Nicole , Adams Erin J. , Herrmann Thomas , Amslinger Sabine 
Published: June 2017

AbstractVγ9Vδ2 T cells play an important role in the cross talk of the innate and adaptive immune system. For their activation by phosphoantigens (PAgs), both cell surface receptors, the eponymous Vγ9Vδ2 T cell antigen receptors (Vγ9Vδ2 TCRs) on Vγ9Vδ2 T cells and butyrophilin 3A1 (BTN3A1) on the phosphoantigen‐“presenting” cell, are mandatory. To find yet undetected but further contributing proteins, a biotinylated, photo‐crosslinkable benzophenone probe BioBP‐HMBPP (2) was synthesized from a known allyl alcohol in nine steps and overall 16 % yield. 2 is based on the picomolar PAg (E)‐4‐hydroxy‐3‐methylbut‐2‐enyl diphosphate (HMBPP, 1). Laser irradiation of 2 at 308 nm initiated the photo‐crosslinking reaction with proteins. When the B30.2 domain of BTN3A1, which contains a positively charged PAg‐binding pocket, was exposed to increasing amounts of HMBPP (1), labeling by BioBP‐HMBPP (2) was reduced significantly. Because BSA labeling was not impaired, 2 clearly binds to the same site as natural ligand 1. Thus, BioBP‐HMBPP (2) is a suitable tool to identify co‐ligands or receptors involved in PAg‐mediated T cell activation.
Polar Intermetallics Pr5Co2Ge3 and Pr7Co2Ge4 with Planar Hydrocarbon‐Like Metal Clusters
Authors: Lin Qisheng , Aguirre Kaiser , Saunders Scott M. , Hackett Timothy A. , Liu Yong , Taufour Valentin , Paudyal Durga , Budko Sergey , Canfield Paul C. , Miller Gordon J. 
Published: June 2017

AbstractPlanar hydrocarbon‐like metal clusters may foster new insights linking organic molecules with conjugated π–π bonding interactions and inorganic structures in terms of their bonding characteristics. However, such clusters are uncommon in polar intermetallics. Herein, we report two polar intermetallic phases, Pr5Co2Ge3 and Pr7Co2Ge4, both of which feature such planar metal clusters, namely, ethylene‐like [Co2Ge4] clusters plus the concatenated forms and polyacene‐like [Co2Ge2]n ribbons in Pr5Co2Ge3, and 1,2,4,5‐tetramethylbenzene‐like [Co4Ge6] cluster in Pr7Co2Ge4. Just as in the related planar organic structures, these metal–metalloid species are dominated by covalent bonding interactions. Both compounds magnetically order at low temperature with net ferromagnetic components: Pr5Co2Ge3 through a series of transitions below 150 K and Pr7Co2Ge4 through a single ferromagnetic transition at 19 K. Spin‐polarized electronic structure calculations for Pr7Co2Ge4 reveal strong spin‐orbit coupling within Pr and considerable magnetic contributions from Co atoms. This work suggests that similar structural chemistry can emerge for other rare‐earth/late‐transition‐metal/main‐group systems.
Towards a multilayered permission‐based access control for extending Android security
Authors: Chang Rui , Jiang Liehui , Chen Wenzhi , He Hongqi , Yang Shuiqiao , Jiang Hang , Liu Wei , Liu Yong 
Published: June 2017

SummaryThis paper discusses security issues on the user equipment, which is the “last mile” of social networks. One of the main Achilles' heel of social networks is not the organization of networks themselves, but the user devices, typically Android ones. The existing system of privileges makes it easy to infiltrate the network via applications installed on users' devices. Conventional signature‐based and static analysis methods are vulnerable. Access to privacy‐ and security‐relevant parts of the application programming interface is controlled by the corresponding permission in a manifest file. While requesting access to permissions, it may offer opportunities to malicious codes, which will cause security issues. Few works among permission analysis, however, pay attention to the prevention of permission leakage on both hardware and software frameworks. In this paper we tackle the challenge of providing our multilayered permission‐based security extension scheme on Android platforms. We propose a usage and access control model and an effective method of preventing permission leakage based on ARM TrustZone security extension mechanism. In contrast to previous work, the proposed security architecture provides a permission‐based mandatory access control on Android middleware, Linux kernel, and hardware layers. The evaluation results demonstrate the effectiveness of the proposed scheme in mitigating permission leakage vulnerabilities.
A QoC‐based model for performance and QoE trade‐off in distributed systems
Authors: D'Amato André , Dantas Mario 
Published: June 2017

SummaryThis paper proposes a quality of context (QoC)–based model to enhance trade‐off between system performance and users quality of experience (QoE) in distributed systems. The QoE considers the users subjective perceptions of quality on technology services and depends on context attributes related to the users expectations. In addition, context information can be used to improve performance in context‐aware systems. Therefore, the QoC‐based model proposed in this paper aims to establish performance and QoE trade‐off for resource allocation in distributed systems. With the massive data growth over the past years, the demand for computing capacity has been notably growing in a proportional way. In view of that, the demand for distributed systems has also increased significantly due to the advantages of distributed computing such as cost‐benefit gains, large processing capacity, and an extensive capability for resources sharing. In this sense, the large‐scale utilization of distributed systems has generated problems concerning resource allocation because of the heterogeneous characteristics and continuous evolution of distributed computational devices, resulting in several challenges in terms of environment performance and users' satisfaction trade‐off. The model conceived in this paper provides for an experimental evaluation considering performance and QoE trade‐off by means of simulations. Simulations were performed in order to study complex distributed systems scenarios. Experimental results showed that the proposed QoC model policy has an enhanced performance in comparison with classical approaches.