bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transvaginal extraction of laparoscopic liver resection specimen
Authors: Ersan Veysel , Kayaalp Cuneyt , Aktas Aydin , Gundogan Ersin , Teomete Uygar , Sumer Fatih , Karagul Servet 
Published: December 2017

The application of laparoscopic surgery via the vagina has been introduced at the beginning of this millennium. Here, we report a case of transvaginal extraction of a laparoscopic hepatectomy specimen. An exophytic liver mass originated from segment VI in a 24-year-old female was excised with laparoscopic technique using four trocars (0.5–1.2 cm sizes). The specimen (11 × 8.5 cm) was removed transvaginally instead of an abdominal incision. To the best of our knowledge, only six similar cases have been previously reported, with a patient age range of 32–74 years. Our case, due to younger age, had high cosmetic expectations. Specific to this case, we aimed a better aesthetic outcomes and better convalescence period and, we achieved these objectives. We believe that patient selection and experience on natural orifice specimen extraction were the keys to the success of the operation. We shared this technique with a video presentation.
High level of specific anti-plasmodium falciparum merozoite IgG1 antibodies in rural asymptomatic individuals of dienga, south-eastern Gabon
Authors: Pegha-Moukandja Irène , Imboumy-Limoukou Roméo-Karl , Tchitoula-Makaya Nina , Mouinga-Ondeme Augustin-Ghislain , Biteghe-Bi-Essone Jean Claude , Mba Dieudonne Nkoghe , Lekana-Douki Jean-Bernard , Ndouo Fousseyni S. Toure 
Published: December 2017

Plasmodium falciparum merozoite antigens (PfMAgs) play an essential role in the development of immunity to malaria. Currently, P. falciparum: protein 113 (Pf 113), apical membrane antigen 1 (AMA1), erythrocyte binding antigens (EBA175), and reticulocyte binding protein homologue 5 (RH5) are among the most PfMAgs studied. A comparative analysis of naturally acquired antibodies against these antigens in children would increase our knowledge about the development of protective immunity.
Analysis of antibodies to Pf113, PfAMA1, PfEBA175, and PfRH5 was conducted in rural population during 2013 and 2014. Both prevalence and levels of total IgG anti-PfAMA1 were higher than that of IgG anti-PfEBA175, anti-PfRH5, and anti-Pf113. Seroconversion to PfAMA1 and PfEBA175 occurred moderately in young children and reached to the maximum in adolescent and in adults. High prevalence of IgG anti-Pf113 was observed in young children of 3 to 6 years old in 2013. The four antigens were recognized by IgG 1, 2, 3, and 4 antibodies from a large proportion of the subjects, and all of them induced high levels of specific IgG1 against PfAMA1, PfEBA175, fewer by Pf113 and PfRH5.
Many asymptomatic children had specific IgG1 recognizing multiple antigens, and these IgG1 antibodies could be associated with a reduced risk of developing malaria symptoms.
Az új, csökkentett dózisú, hazai gyártású influenzavakcina (FluArt) forgalomba hozatalát követő első szezonjának biztonságossági vizsgálata
Authors: Vajó Péter , Gyurján Orsolya , Szabó Ágnes Mira , Kalabay László , Vajó Zoltán , Torzsa Péter 
Published: December 2017

Abstract: Introduction: The currently licensed seasonal influenza vaccines contain split, subunit or whole virions, typically in amounts of 15 µg hemagglutinin per virus strain for adult and up to 60 µg in elderly patients. Aim: The present study reports safety data of the newly licensed, reduced dose vaccine with 6 µg of hemagglutinin per strain produced by Fluart (Hungary) after its first season on the market. The main objective of enhanced safety surveillance was to detect a potential increase in reactogenicity and allergic events that is intrinsic to the product in near real-time in the earliest vaccinated cohorts. Method: The study methods were based on the Interim guidance on enhanced safety surveillance for seasonal influenza vaccines in the EU by the European Medicines Agency. Statistics: We used the Fisher exact test with 95% confidence intervals. Results: We studied 587 patients and detected a total 24 adverse events, all of which have already been known during the licensing studies of the present vaccine. The frequencies of the adverse events were not different from what had been seen with the previously licensed 15 µg vaccine. Conclusions: Based on the results, the authors conclude that the new, reduced dose vaccine FluArt is safe and tolerable. Orv Hetil. 2017; 158(49): 1953–1959.
Structural implications of internal swelling reactions in concrete: review and research needs
Authors: Noël Martin , Sanchez Leandro , Tawil Dana 
Published: December 2017

The chemical and physical processes associated with alkali–aggregate reaction and delayed ettringite formation, otherwise known as internal swelling reactions (ISRs), have been the subject of considerable research spanning several decades, yet the implications for affected structures are still open to debate. A major knowledge gap currently exists between the diagnosis and prognosis of ISR mechanisms, and the quantification and management of risk associated with ISR expansion in structures. This lack of understanding of the effects of ISRs on structural behaviour may be attributed to the fact that parameters such as confinement, boundary conditions, anisotropy and loading conditions are complex and vary greatly in existing structures. Furthermore, the correlation between the results of microscopic/macroscopic analyses on concrete core samples and the in situ performance of large-scale structures is still not well understood, even at a fundamental level. The aim of this paper is to summarise current knowledge of the structural implications of ISR mechanisms in concrete structures and stimulate a discussion of the importance of pursuing multi-scale experimental testing programs for the assessment of ageing infrastructure. A parametric analysis is included using the software VecTor2.
The Coupling of Second Language Learning Motivation and Achievement According to Gender
Authors: Mady Callie , Seiling Alexandra 
Published: December 2017

Despite research investigating gender differences in second language motivation, the examination of such differences with a coupling of motivation and achievement evidence is less common. Given that increased motivation is a contributory factor of achievement (e.g., Schmidt et al., 2001) where gender can also be an influencing variable, it is important to examine the influence of gender on motivation and proficiency in second language education. The following article explores the motivation of 87 Grade 6 early French immersion students through the means of a questionnaire, grounded in Gardner’s socio-educational (1985) and MacIntyre’s (1994) willingness to communicate models. Through multiple regression analysis, the questionnaire findings were examined to see, which if any, variables predicted French proficiency as measured through a multi-skills French test. The female participants outperformed the males in French reading, writing and speaking, whereas only one significant difference was found on the questionnaire items (i.e., language awareness). Although the multiple regression analyses showed both increases and decreases in French achievement according to questionnaire items, where there were significant differences being female was associated with increases in French achievement. These findings offer a gateway to further research, as educators strive to offer quality second language education to all.
The Effect of Junior High School Teachers' Motivation and Willingness to Change on the Diversity of Their Teaching Methods
Authors: Zeid Hanan Abu , Assadi Nabil , Murad Tareq 
Published: December 2017

This study attempts examine the influence of motivation and willingness of teachers to change on the diversity of teaching methods. The research question is: What is the influence of junior school teachers' motivations and willingness to change on the diversity of their teaching instructions? The participants of the study are 50 English teachers of Junior High Schools in Northern Israel. The research instruments were three questionnaires. The research’s findings revealed a significant influence of English teachers of Junior High Schools willingness to change on the diversity of teaching methods; the higher the willingness to change, the diversity in teaching modes increases. Another significant effect was also found between the level of teaching motivation and diversity of teaching methods; teachers with high motivation level reported diversification in teaching methods. A final significant effect of level of general motivation and willingness for change was also found; the willingness for change among teachers of high motivation increased. The main research conclusion is that willingness to change, which is connected to motivation, influences the diversity of teaching methods. Therefore, in order to assimilate changes in teachers’ working modes, like diversifying their teaching methods or in any other way, there is a need to encourage and nurture their motivation.
Association of Fat Mass and Obesity-associated Gene (FTO) rs9939609 Variant with Early Onset Obesity among Bataknese and Chinese Children in Indonesia: A Case-control Study
Authors: Lubis Siska Mayasari , Fattah Miswar , Damanik Harun Alrasyid , Batubara Jose Rizal Latief 
Published: December 2017

BACKGROUND: Childhood obesity is associated with the risk of adult obesity and obesity-related chronic disease. The fat mass and obesity-associated gene (FTO) rs9939609 variant are of particular interest because of its association with body mass index (BMI) and obesity-related phenotypes. This study was conducted to investigate the association between FTO gene rs9939609 variant with early onset obesity among Bataknese and Chinese children in Medan, Sumatera Utara, Indonesia.METHODS: The case-control study was carried out at 10 elementary schools in Medan. There were 212 children recruited; 56 early onset obesity and 61 control Bataknese and 49 early onset obesity and 46 control Chinese children. This study included a questionnaire, anthropometric measurements, and blood test analysis. rs9939609 polymorphism genotyping was performed using RT-PCR. Logistic regression, odds ratio (OR) and 95% confidence interval (CI) were calculated to determine the risk of obesity associated with the risk alleles, p<0.05 was considered as statistically significant.RESULTS: This study found a significant association between rs9939609 and early onset obesity in Chinese children (p=0.01), but not in Bataknese. The frequency of AA genotype was lower in the early onset obesity than in the normal weight children, while an OR of 0.69 showed that this genotype may protect against weight gaining and that the TT genotype may predispose to obesity.CONCLUSION: We concluded that the FTO gene rs9939609 is associated with early onset obesity in Chinese ethnicity but not in Bataknese.KEYWORDS: pediatric obesity, FTO gene, rs9939609, polymorphism, Indonesia
Telomere in Aging and Age-Related Diseases
Authors: Meiliana Anna , Dewi Nurrani Mustika , Wijaya Andi 
Published: December 2017

BACKGROUND: The number of elderly population in the world keep increasing. In their advanced ages, many elderly face years of disability because of multiple chronic diseases, frailty, making them lost their independence. Consequently, this could have impacts on social and economic stability. A huge challenge has been sent for biomedical researchers to compress or at least eliminate this period of disability and increase the health span.CONTENT: Over the past decades, many studies of telomere biology have demonstrated that telomeres and telomere-associated proteins are implicated in human diseases. Accelerated telomere erosion was clearly correlated with a pack of metabolic and inflammatory diseases. Critically short telomeres or the unprotected end, are likely to form telomeric fusion, generating genomic instability, the cornerstone for carcinogenesis. Enlightening how telomeres involved in the mechanisms underlying the diseases’ pathogenesis was expected to uncover new molecular targets for any important diagnosis or therapeutic implications.SUMMARY: Telomere shortening was foreseen as an imporant mechanism to supress tumor by limiting cellular proliferative capacity by regulating senescence check point activation. Many human diseases and carcinogenesis are causally related to defective telomeres, asserting the importance of telomeres sustainment. Thus, telomere length assessment might serve as an important tool for clinical prognostic, diagnostic, monitoring and management.KEYWORDS: telomerase, cellular senescence, aging, cancer
La producción fotográfica escolar de Ezequiel Fernández Santana 100 años después (1915-2015)
Authors: Soto Vázquez José , Pérez Parejo Ramón 
Published: December 2017

Recientes estudios han demostrado las interesantes aportaciones de la fotografía escolar al ámbito de la investigación en Historia de la Educación. En este contexto, las fotografías de Ezequiel Fernández Santana, tomadas entre 1915 y 1938, constituyen un hito en la historia de la fotografía escolar de España. Los cristales originales fueron hallados en un vertedero, después fueron restaurados y digitalizados, según los criterios contemporáneos para fondos documentales, así como catalogados para su correcta identificación, cronología, y tema. Su conservación actual permitirá el estudio de la fotografía escolar con fines artísticos y propagandísticos, dado que estos materiales constituyen un ejemplo único en este sentido. El corpus supone un material inédito y exclusivo, no solo por proceder de un mismo fotógrafo, sino también por su cantidad (220 imágenes), su unidad temática, y su perspectiva pedagógica. De este modo se aúna en su figura el valor de la fotografía tomada in media res por el mismo maestro.
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Contextualización: Idioma Maya Mam
Contextualizador: Rosendo Ordóñez Maldonado
Ministerio de Educación de Guatemala
CH’IN TUMILAL
Matz’el nikyb’aj ti’j tb’inchb’en tib’lal jaku onin nimxix ti’j xpich’b’il ti’j tza’n matzaj b’et xnaq’tzb’il teitz tx’otx’ kyxol, xjal. Atzun txilen qe tib’lal machib’ant tu’n Ezequiel Fernández Santana tuj t-ab’q’iyil 1915 ex 1938, ntq’ama’n txilen titz’jleni qe tib’lal toj xnaq’tzb’il twitz kytx’otx’ kyxe’cil amq’ jlajxi nim a’. Nti’taq okq’0’n kyipumal tej kykanet tnejil kyu’n xjal toj jun tenb’il nyaxix tb’anil, oktzun jun aq’untl ti’j tun tb’aj b’inchet ex tu’n tkoletqe kyjatzun okq’o’n xpich’b’il ti’j jatumil itzaj kanet ex ti’ nkyq’ama’n tuj ju’jun anb’il tej kyb’inchet. Atzun jun kyb’an ja’lu tu’n tb’aj q’amet ex tu’n txiyek’at tonb’il ti’j ju’njun xnaq’tzb’il ex tza’n tu’n tajb’en qu’n tuj tumilalxix. Kyaqiltzun b’ib’il aju nti’ lo’maj kyu’n xjal, b’ele tu’ntlaj taq’anb’en junx xjal y nimxix tajlal tu’n tb’aj nuk’b’et, ti’j xnaq’tzb’il ex tu’n tel qniky’ ti’ ntaq’a’n ju’jun tib’lal. Kyjatzun a jun tumilal nkyq’ama’n tib’lal twitz qnab’il ntzaj qe’ tmij jun tanq’ib’il xjal

Tipumal yol: Ujb’il q’ol tnab’il xnaq’tzb’il; b’inchab’il; yek’b’il ex xnaq’tzb’il; jaxnaq’tz, tib’lal
Utilization of Supported Liquid Membrane (SLM) in Separation of Pb(II) by Varying Concentration of Carrier and Feed Solution
Authors: Indarti Dwi , Novitasari Novitasari , Sulistyo Yudi Aris 
Published: December 2017

Supported liquid membrane (SLM) was prepared by reacting host material with carrier compounds. Carrier compound was Polyethylene Glycol-400 (PEG-400) that have been used with the variation of concentration 0, 2, 4, and 6%. The effect of its variations in SLM was characterized by FTIR and the performance was examined by transporting feed solution Pb(NO3)2 with variation 1, 5, 10, 15, and 25 ppm for 3 hours in pH 3. FTIR spectra depicted that the increasing concentration of PEG would arise the intensity of typical PEG’s functional groups such as -OH, C-O-C, and CH2-CH2 sp3. The optimum transport Pb(II) was achieved by SLM with 6% PEG. Variation of feed solution concentration showed the main effect in SLM activity. The higher of feed solution concentration would decrease of transport activity. The % extract and % recovery 1 ppm was higher than 25 ppm with 72,5% and 70,27% than 6,1% and 3,59%, respectively.
Keywords: supported liquid membrane, Pb(II), poly ethylene glycol, extraction and recovery, carrier compound
INTEGRATING THE ROLES OF STAKEHOLDERS IN PREVENTING THE HIV/AIDS TRANSMISSION IN EAST JAVA, INDONESIA
Authors: Koesbardiati Toetik , Kinasih Sri Endah , Mas’udah Siti 
Published: December 2017

HIV/AIDS prevention is very important and absolutely necessary. HIV transmission is now entering a fairly alarming level, in which people with HIV/AIDS in certain subpopulations are emerging. Special steps and resources are thus needed to cope with the condition. There are some phenomena potentially encourage HIV transmissions, such as the increasingly common free sex, homosexuality, the use of unsafe and unsterile syringes in narcotics consumption, commercial sex workers and various high-risk sexual activities. One of the crucial concerns that arises when sending prostitutes back to their hometowns without any coordinated and holistic mechanism is that the prostitutes may cause the spreading of HIV/AIDS in their hometowns. The research objective is to provide the material (input) how the prostitutes themselves may cause the spreading of HIV/AIDS. The research employed descriptive method with a qualitative approach. The results showed that the implementation and the role division in the closure have been highly coordinated and holistic. The leading sector in the role division is the Social Welfare epartment of the Government in Surabaya. In terms of health aspects for the former prostitutes sent back to their hometowns, there has been no policies related to medical screening designed to identify the disease early. Screening is very important for early diagnosis during the post-closure phase. The screening mechanism is that the Provincial Health Department has to optimize the monitoring, coordination, cooperation, agreements and partnerships with stakeholders such as the Local Health Department and the National/Provincial/Distric AIDS Commission, NGOs that are concerned with the problems of HIV-AIDS, international organizations, professional organizations, community leaders, religious leaders and universities.
DNA Microarray for Rapid Detection and Identification of Food and Water Borne Bacteria: From Dry to Wet Lab
Authors: Ranjbar Reza , Behzadi Payam , Najafi Ali , Roudi Raheleh 
Published: December 2017

Background:A rapid, accurate, flexible and reliable diagnostic method may significantly decrease the costs of diagnosis and treatment. Designing an appropriate microarray chip reduces noises and probable biases in the final result.Objective:The aim of this study was to design and construct a DNA Microarray Chip for a rapid detection and identification of 10 important bacterial agents.Method:In the present survey, 10 unique genomic regions relating to 10 pathogenic bacterial agents includingEscherichia coli (E.coli), Shigella boydii, Sh.dysenteriae, Sh.flexneri, Sh.sonnei, Salmonella typhi, S.typhimurium, Brucella sp., Legionella pneumophila,andVibrio cholerawere selected for designing specific long oligo microarray probes. For this reason, the in-silico operations including utilization of the NCBI RefSeq database, Servers of PanSeq and Gview, AlleleID 7.7 and Oligo Analyzer 3.1 was done. On the other hand, thein-vitropart of the study comprised stages of robotic microarray chip probe spotting, bacterial DNAs extraction and DNA labeling, hybridization and microarray chip scanning. In wet lab section, different tools and apparatus such as Nexterion® Slide E, Qarrayminispotter, NimbleGen kit, TrayMixTMS4, and Innoscan 710 were used.Results:A DNA microarray chip including 10 long oligo microarray probes was designed and constructed for detection and identification of 10 pathogenic bacteria.Conclusion:The DNA microarray chip was capable to identify all 10 bacterial agents tested simultaneously. The presence of a professional bioinformatician as a probe designer is needed to design appropriate multifunctional microarray probes to increase the accuracy of the outcomes.
FATORES ASSOCIADOS ÀS INFECÇÕES SEXUALMENTE TRANSMISSÍVEIS EM USUÁRIOS DE CENTRO DE TESTAGEM E ACONSELHAMENTO DA BAHIA
Authors: Ferraz Segundo Flávio Laranjeira , Davoglio Rosane Silvia , Sousa Luise Maria , Canário Djulian Diego Ribeiro do Carmo , Nascimento Ananda Ariane Januário do , Coelho Glória Maria Pinto 
Published: December 2017

As Infecções Sexualmente Transmissíveis constituem importante determinante da carga de doenças na população, principalmente em países subdesenvolvidos e em desenvolvimento. O objetivo deste estudo foi investigar a prevalência e fatores associados a Infecções Sexualmente Transmissíveis em usuários de um Centro de Testagem e Aconselhamento da Bahia. Estudo analítico observacional transversal com 880 participantes, desenvolvido em 2011. Os dados foram coletados dos Formulários de Entrada do Sistema de Informações do Centro de Testagem e Aconselhamento, folha de descrição de atendimentos do usuário e prontuário clínico. Foram realizadas análises univariada e multivariada por Regressão de Poisson. Os resultados mostraram uma prevalência de Infecções Sexualmente Transmissíveis de 11,1%. O HIV foi o agravo mais prevalente (4,2%), seguido da sífilis (4%) e hepatites B (2,1%) e C (2,1%). O uso consistente de preservativo foi baixo, com parceiros fixos (9,5%) e não fixos (16,2%). Na análise ajustada, associaram-se estatisticamente ao desfecho: idade acima de 35 anos, escolaridade entre 8 e 11 anos, origem da clientela de serviços/profissionais de saúde e indicação de amigos/usuários, e preferência por relações homossexuais. Concluiu-se que foi elevada a prevalência de Infecções Sexualmente Transmissíveis em usuários do Centro de Testagem e Aconselhamento estudado, e associaram-se às variáveis sociodemográficas e comportamentais.
Palavras-chave: Infecções sexualmente transmissíveis. Doenças sexualmente transmissíveis. Sorodiagnóstico de HIV/Aids. Hepatite. Sífilis.
INFLUÊNCIA DAS DESIGUALDADES ECONÔMICAS E SANITÁRIAS NA INCIDÊNCIA DA DIARREIA INFANTIL EM MINAS GERAIS, 2010
Authors: André Sílvia Carla da Silva , Dos Santos Ana Paula Milla , Veiga Tatiane Bonametti , Magosso Takayanagui Angela Maria 
Published: December 2017

O objetivo deste estudo foi investigar a associação entre o tipo de disposição final dos resíduos sólidos urbanos e renda per capita com a incidência de internações por diarreia em crianças menores de cinco anos. O estudo epidemiológico, do tipo ecológico e descritivo, foi realizado com dados da Fundação Estadual do Meio Ambiente de Minas Gerais e do Departamento de Informática do Sistema Único de Saúde para 2010. Foram estudadas a incidência de internações por diarreia das regiões do Vale do Jequitinhonha e Triângulo Mineiro, do estado de Minas Gerais. Os dados foram analisados por ANOVA, teste de comparação múltipla de Tukey, cálculo do coeficiente de Pearson e risco relativo, por meio do software SigmaStat, versão 3.5. Os resultados indicaram que a incidência de internações por diarreia em menores de cinco anos foi maior em municípios da região do Vale do Jequitinhonha com disposição final dos resíduos em lixões e com menor renda per capita. Concluiu-se que é necessária a implementação de melhorias intersetoriais para reduzir a morbimortalidade infantil, em especial em regiões mais carentes.
Palavras-chave: Saúde pública. Saúde ambiental. Diarreia infantil. Eliminação de resíduos. Renda per capita.