bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uric Acid and Neurocognitive Function in Survivors of Childhood Acute Lymphoblastic Leukemia Treated with Chemotherapy Only
Authors: Cheung Yin Ting , Edelmann Michelle N. , Mulrooney Daniel A. , Green Daniel M. , Chemaitilly Wassim , John Neena , Robison Leslie L. , Hudson Melissa M. , Krull Kevin R. 
Published: June 2016

Abstract
Background: Hyperuricemia is implicated in cardiovascular and cerebrovascular diseases. This study evaluated associations between uric acid (UA), cardiovascular health, and neurocognitive function in adolescent and adult survivors of childhood acute lymphoblastic leukemia treated with chemotherapy only.
Methods: 126 adolescent [mean (SD) age 14.6 (5.0); 7.8 (1.7) years postdiagnosis] and 226 adult survivors [age 25.4 (4.2) years; 18.1 (4.4) years postdiagnosis] completed comprehensive neurocognitive testing. Concurrent UA measurements were conducted for both groups. For adult survivors, cardiovascular risk factors were assessed, and UA measurements during adolescence [12.3 (4.0) years before neurocognitive testing] were also collected. UA levels were categorized into quartiles for age- and gender-based ranking, and associations with neurocognitive outcomes were examined.
Results: Survivors demonstrated worse attention, processing speed, and executive functions than population norms (P values &lt; 0.05). Adolescent survivors with elevated UA had poorer attention (P = 0.04), visual-processing speed (P = 0.03), and cognitive flexibility (P = 0.02). UA was not associated with neurocognitive outcomes in adult survivors. Adult survivors developed dyslipidemia (46%), hypertension (32%), and abdominal obesity (26%), and high UA during adolescence was associated with these cardiovascular risk factors as adults (all P values &lt; 0.01). Fine-motor processing speed was slower in adult survivors with dyslipidemia (P = 0.04) and abdominal obesity (P = 0.04). Poorer attention was marginally associated with hypertension (P = 0.06).
Conclusions: Elevated UA is associated with neurocognitive performance in adolescent survivors. In adult survivors, relative elevation of UA during adolescence was predictive of cardiovascular health, which was associated with poorer neurocognitive outcomes.
Impact: Future studies should evaluate the mediating role of chronic cardiovascular health conditions between elevated UA and subsequent neurocognitive impairment in survivors. Cancer Epidemiol Biomarkers Prev; 25(8); 1259–67. ©2016 AACR.
Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation
Authors: Zou Siying , Teixeira Alexandra M. , Yin Mingzhu , Xiang Yaozu , Xavier-Ferruccio Juliana , Zhang Ping-xia , Hwa John , Min Wang , Krause Diane S. 
Published: June 2016

SummaryLeukemia-Associated RhoGEF (LARG) is highly expressed in platelets, which are essential for maintaining normal haemostasis. We studied the function of LARG in murine and human megakaryocytes and platelets with Larg knockout (KO), shRNA-mediated knockdown and small molecule-mediated inhibition. We found that LARG is important for human, but not murine, megakaryocyte maturation. Larg KO mice exhibit macrothrombocytopenia, internal bleeding in the ovaries and prolonged bleeding times. KO platelets have impaired aggregation, α-granule release and integrin α2bβ3 activation in response to thrombin and thromboxane, but not to ADP. The same agonist-specific reductions in platelet aggregation occur in human platelets treated with a LARG inhibitor. Larg KO platelets have reduced RhoA activation and myosin light chain phosphorylation, suggesting that Larg plays an agonist-specific role in platelet signal transduction. Using two different in vivo assays, Larg KO mice are protected from in vivo thrombus formation. Together, these results establish that LARG regulates human megakaryocyte maturation, and is critical for platelet function in both humans and mice.Supplementary Material to this article is available online at www.thrombosis-online.com.
Timing of anticoagulation therapy in patients with acute ischaemic stroke and atrial fibrillation
Authors: Paciaroni Maurizio , Agnelli Giancarlo , Ageno Walter , Caso Valeria 
Published: June 2016

SummaryIn patients with acute stroke and atrial fibrillation (AF), the risk of early recurrence has been reported to range between 0.1% and 1.3% per day. Anticoagulants are the most effective therapy for the prevention of recurrent ischaemic stroke in these patients, but randomised clinical trials have failed to produce any evidence supporting the administration of heparin within 48 hours from stroke onset as it has been associated with a non-significant reduction in the recurrence of ischaemic stroke, no substantial reduction in death and disability, and an increase in intracranial bleeding. As early haemorrhagic transformation is a major concern in the acute phase of stroke patients with AF, determining the optimal time to start anticoagulant therapy is essential. This review which focuses on the epidemiology of recurrent ischaemic stroke and haemorrhagic transformation in patients with acute ischaemic stroke and AF, proposes a model for decision making on optimal timing for initiating anticoagulation, based on currently available evidence.
Notes on three new records of foliicolous lichens from Karnataka Western Ghats, India
Authors: Kumar S. Shravan , Krishnamurthy Y. L. 
Published: June 2016

The paper describes Bapalmuia palmuaris, Byssoloma leucoblepharum and Gyalectidium filicinum as a new record of foliicolous lichens from the Western Ghats parts of Karnataka, India. A brief taxonomic description, remarks, ecological notes and distribution details are provided.
On the reproductive ecology of Suaeda maritima, S. monoica and S. nudiflora (Chenopodiaceae).
Authors: Raju A.J. Solomon , Kumar Rajendra 
Published: June 2016

Floral biology, sexual system, breeding system, pollinators, fruiting and seed dispersal aspects of three Suaeda species, S. maritima, S. monoica and S. nudiflora (Chenopodiaceae) were studied. The flowers of all the three species are hermaphroditic, dichogamous, strongly protogynous with a pistillage phase during the mature bud stage and staminate phase following anthesis, self-compatible exhibiting mixed breeding systems with special adaptation for cross-pollination; but both self- and cross-pollination are vector-dependent. In all, the flowers display a mix of anemophilous and entomophilous traits. Anemophily is effective in high salt marshes while water currents bring about pollination in low salt marshes; insects pollinate the flowers while collecting the forage from pistillate and staminate phase flowers. In these species, the whole plant breaks off and rolls on the floor while shedding its diaspores. Fruits with seeds intact and/or seeds shed from fruits float on water due to their ability for buoyancy. The fruits and seeds thus disperse, settle in the entire extent of salt marshes or coastal areas and germinate in mid-summer season when salinity is very high in high and low salt marshes.
Perch height and the hunting success of the Indian Eagle Owl Bubo bengalensis (Franklin) (Aves: Strigiformes: Strigidae) targeting anuran prey.
Authors: Ramanujam Eric 
Published: June 2016

Investigation into the predation of a pair of Indian Eagle Owls on anurans disclosed the fact that the greatest success (52.17%) was when the owls pounced from a height of less than 2m and the lowest (12.5%) was from a height of 5–6 m. No success was recorded when the owls pounced from over a height of 6m or when they tried wading in water to catch their prey. Overall, 146 pounces were observed and the strike success was 28.7%.
The impact of Craigslist’s entry on competing employment websites
Authors: Brenčič Vera 
Published: June 2016

Abstract
Craigslist, a website that hosts job- and help-wanted ads, expanded rapidly across the states in the USA over a very short period of time, thereby changing abruptly the market structure faced by competing employment websites. We exploit this abrupt change to evaluate its impact on competing websites’ online traffic and pricing. We find that Craigslist’s entry was associated with a decrease in the number of visitors that an average competing employment website attracted and with a decrease in the number of pages an average visitor reviewed during a typical visit. We also find that employment websites lowered some of the fees they charged their users. Overall, these findings offer one explanation for why Craigslist, despite its popularity, had little effect on the unemployment rate in the labor markets it entered: the entry of Craigslist cannibalized online traffic at competing employment websites.

JEL Classification: J20, L10, L86
Partners’ leisure time truly together upon retirement
Authors: Stancanelli Elena , Van Soest Arthur 
Published: June 2016

Abstract
Externalities in leisure are considered an important reason for partners’ joint retirement. This study quantifies the extent to which partners actually spend more leisure time “together” at retirement. Exploiting legal retirement age in France, we identify the effect of retirement on partners’ hours of leisure, distinguishing leisure hours spent together or not. We find that the separate leisure demand of the husband increases dramatically upon his retirement, by about 3 h per day. The wife’s retirement significantly increases both her separate leisure time and the couple’s joint leisure time. Because the wife is typically the last to retire, her retirement often coincides with partners’ joint retirement. Our findings confirm that leisure complementarities in retirement are significant though perhaps not very large quantitatively.

Jel codes: C26, C31, J26, J22
Methodology for the design, production, and test of plastic optical displacement sensors
Authors: Rahlves Maik , Kelb Christian , Reithmeier Eduard , Roth Bernhard 
Published: June 2016

Abstract
Optical displacement sensors made entirely from plastic materials offer various advantages such as biocompatibility and high flexibility compared to their commonly used electrical and glass-based counterparts. In addition, various low-cost and large-scale fabrication techniques can potentially be utilized for their fabrication. In this work we present a toolkit for the design, production, and test of such sensors. Using the introduced methods, we demonstrate the development of a simple all-optical displacement sensor based on multimode plastic waveguides. The system consists of polymethylmethacrylate and cyclic olefin polymer which serve as cladding and core materials, respectively. We discuss several numerical models which are useful for the design and simulation of the displacement sensors as well as two manufacturing methods capable of mass-producing such devices. Prior to fabrication, the sensor layout and performance are evaluated by means of a self-implemented ray-optical simulation which can be extended to various other types of sensor concepts. Furthermore, we discuss optical and mechanical test procedures as well as a high-precision tensile testing machine especially suited for the characterization of the opto-mechanical performance of such plastic optical displacement sensors.
Explaining the Equalising Effect of Panel-Income Changes
Authors: Herault Nicolas 
Published: June 2016

Abstract
Panel-income changes tend to be equalising but existing approaches provide little insight on the nature of this equalising process. I present a new decomposition framework showing explicitly how the equalising effect of panel-income changes depends on the respective size and distribution of panel-income gains and losses. One of the new insights gained from the application to US data for the 1970/2009 period is that most of the equalising effect occurs through income gains rather than income losses even in times of recession.
Qualitative and quantitative central bank communication and inflation expectations
Authors: Hubert Paul 
Published: June 2016

Abstract
We aim to investigate the simultaneous and interacted effects of central bank qualitative and quantitative communication on private inflation expectations, measured with survey and market-based measures. The effects of ECB inflation projections and Governing Council members’ speeches are identified through an instrumental-variables estimation using a principal component analysis to generate relevant instruments. We find that ECB projections have a positive effect on current-year forecasts, and that ECB projections and speeches are substitutes at longer horizons. Moreover, ECB speeches and the ECB rate reinforce the effect of ECB projections when they are consistent, and convey the same signal about inflationary pressures.
Evaluation of Radiological Hazards of Particulates Emissions From a Coal Fired Power Plant
Authors: Suhana J. , Rashid M. 
Published: June 2016

Abstract
Natural minerals may contain radionuclides of natural origin of Uranium-238 (238U) and Thorium-232 (232Th) decay series. Similarly, coal like any other minerals found in nature contains trace amount of such naturally occurring radionuclides including Potassium-40 (40K). The generation of electricity by coal fired power plant (CFPP) releases particulates emission to the atmosphere and deposited on the surrounding area that may increase the natural background radiation level within the facility. This paper presents an evaluation of the natural radioactivity concentration found in the particulates emission from a typical CFPP in Malaysia. Standard Gaussian dispersion model approach was used to predict the potential radiological hazards arising from the particulates released from the stack. The predicted maximum ground level particulate (Cmax) concentration and downwind distance (X) was 52 µg m–3 and 1,600 m of away from the CFPP, respectively. The air dispersion modelling results recorded that the calculated Cmax released from the CFPP was found lower than the national and international ambient air quality limits, which means that radiological hazards due to inhalation of natural radionuclides in particulate released to the environment is insignificant. The findings revealed that, this activity does not impose any significant radiological risk to the human population at large and the operation is in compliance with the national legislation and international practice.
An Environmental Impact Assessment of the underground operations at the designed Petrikov potash mine, Belarus
Authors: Barbikov Dmitry V. , Grechko Anatoly M. , Savchenko Vladimir V. , Zlebova Anzhelika E. , Kurlovich Dmitry M. , Sauchyk Siarhei F. 
Published: June 2016

Abstract
The Petrikov deposits of potash salt is situated in Gomel oblast of Belarus in the south-east of Pripyat Trough, and have Northern and Southern prospects. Underground mining of potash salt will start at the Northern prospect with an area of 166 km2. It is expected that mining will last for between 50-80 years. An Environmental Impact Assessment (EIA) was carried out at the design stage of the Petrikov mining and processing plant. The standard EIA procedure included a set of investigations, including assessments of surface subsidence, changes in groundwater level, changes in productivity of forest phytocoenoses and crops, and assessment of groundwater pollution due to production of potash fertilizers. Maximum values of possible surface subsidence (up to 2.3 m) will occur within the area, where the surface will be affected by the mining of potash layers 1, 2, and 3 of the productive horizon IV-Π, using a long-pillar mining system. Surface subsidence will influence surface topography, surface and groundwater, landscape structure and land resources. The result of surface subsidence will lead to inundation and swamping of land, as well as to an increase in the areas affected by annual floods in the valleys of the Pripyat and Bobrik rivers. Surface subsidence will affect the whole area of the prospect within the limits of planned mining fields, except the areas above safety pillars. In the result of raised groundwater levels the area with groundwater depth of more than 2 m will decrease from 69.1% to 17.8%, and the areas with groundwater depth from 3 to 5 m will disappear. The area with a groundwater depth less than 1 m will increase from 0.1% to 34.0%. In 19.5% of the area the groundwater level will raise above the surface level (the area of inundation). Surface subsidence and change in groundwater level will cause certain decreases in yields of timber and crops, and 2564 ha of forest, 68 ha of arable land and 324 ha of meadows will be inundated. In order to prevent inundation within certain areas protective engineering facilities have been designed, and an arrangement of groundwater monitoring wells has been proposed.
Review of Magnetron Developments
Authors: Vyas Sandeep Kumar , Verma Rajendra Kumar , Maurya Shivendra , Singh V.V.P. 
Published: June 2016

AbstractMagnetrons have been the most efficient high power microwave sources for decades. In the twenty-first century, many of the development works are headed towards the performance improvement of CW industrial magnetrons. In this review article, the development works and techniques, used on different types of magnetrons, for the performance enhancement in the past two decades have been discussed. The article focuses on the state of the art of CW magnetron and the direction it will take in foreseeable future. In addition it also glimpses some of the major variants of magnetron which have further opened up scope in mm-THz spectrum of electromagnetism.
Nous Sommes Charlie: Discussing the EU Reaction to the Growing Risk of Terrorist Attacks
Authors: Capone Francesca 
Published: June 2016

AbstractIn the aftermath of the deadly attacks occurred in France at the beginning of 2015 the European Union has faced an unprecedented wave of terrorism which has led to the adoption of new measures set up to counter the increasing risk of further offences. Terrorism is not new on the EU agenda, in particular since 2001. Several EU Member States have been directly involved in the US “war on terror”, triggered by the 9/11 attacks. In the following years the tragic events occurred in Madrid and London have urged the EU to design a comprehensive counter-terrorism strategy, which is based on four pillars i. e. prevention, protection, pursuit and response. The terrorist attacks carried out in January 2015 have marked the beginning of a new era in the struggle against terrorism and have prompted the adoption of a new policy, based on enhancing citizens’ security, prevention and international cooperation, which added an additional layer to the EU strategy already in place. Despite the immediate response, a few months later Paris and the whole Europe have suffered from an even more dreadful attack, which led to question the effectiveness of the newly adopted approach. In light of the current developments, this contribution has a twofold purpose.
Being Dementia Smart (BDS): A Dementia Nurse Education Journey in Scotland
Authors: Macaden Leah 
Published: June 2016

AbstractThere is a global demographic transition secondary to population ageing. The number of older people living with multimorbidities including dementia has been significantly rising both in developed and developing countries. It is estimated that there would be 74.7 million people living with dementia by 2030 that would escalate to 135.46 million by 2050. 62 % of people with dementia currently live in low and middle income countries that are very poorly resourced to cope with this epidemic. Dementia is now duly recognised as a national priority within the UK and a global priority at the 2013 G8 Summit. Management and care of an individual with dementia requires a multidisciplinary approach with expertise and a competent skill base. Nurses are central to the delivery of dementia care delivery in hospitals, community and residential care settings. It is against this background that this pre-registration integrated dementia curriculum was developed to build capacity and capability with dementia expertise among the future nursing workforce in Scotland in line with the National Dementia Strategy.
Scalable business intelligence with graph collections
Authors: Petermann André , Junghanns Martin 
Published: June 2016

Abstract
Using graph data models for business intelligence applications is a novel and promising approach. In contrast to
traditional data warehouse models, graph models enable the mining of relationship patterns. In our prior work, we
introduced an approach to graph-based data integration and analytics called BIIIG (Business Intelligence with Integrated
Instance Graphs). In this work, we compare state-of-the-art systems for graph data management and analytics with regard to
the support for our approach in Big Data scenarios. To exemplify the analytical value of graph models for business
intelligence, we propose an analytical workflow to extract knowledge from graph-integrated business data. Finally, we show
how we use Gradoop, a novel framework for distributed graph analytics, to implement our approach.
Clustering Big Data streams: recent challenges and contributions
Authors: Hassani Marwan , Seidl Thomas 
Published: June 2016

Abstract
Traditional clustering algorithms merely considered static data. Today's various applications and research issues
in big data mining have however to deal with continuous, possibly infinite streams of data, arriving at high
velocity. Web traffic data, surveillance data, sensor measurements and stock trading are only some examples of
these daily-increasing applications.
Since the growth of data volumes is accompanied by a similar raise in their dimensionalities, clusters cannot be
expected to completely appear when considering all attributes together. Subspace clustering is a general approach that
solved that issue by automatically finding the hidden clusters within different subsets of the attributes rather than
considering all attributes together.
In this article, novel methods for an efficient subspace clustering of high-dimensional big data streams are
presented. Approaches that efficiently combine the anytime clustering concept with the stream subspace clustering paradigm
are discussed. Additionally, efficient and adaptive density-based clustering algorithms are presented for high-dimensional
data streams. Novel open-source assessment framework and evaluation measures are additionally presented for subspace
stream clustering.