bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUMAN PHENOTYPIC MORALITY AND THE BIOLOGICAL BASIS FOR KNOWING GOOD
Authors: Rappaport Margaret Boone , Corbally Christopher 
Published: August 2017

AbstractCo‐creating knowledge takes a new approach to human phenotypic morality as a biologically based, human lineage specific (HLS) trait. Authors from very different backgrounds (anthropology and biology, on the one hand, and astronomy, philosophy, and theology, on the other) first review research on the nature and origins of morality using the social brain network, and studies of individuals who cannot “know good” or think morally because of brain dysfunction. They find these models helpful but insufficient, and turn to paleoanthropology, cognitive science, and neuroscience to understand human moral capacity and its origins long ago, in the genus Homo. An unusual narrative capturing “morality in action” takes the reader back 900,000 years, and then the authors analyze the essential features of moral thinking and behavior as expressed by early and later species on our lineage. In what has primarily been the province of philosophers to date, the authors’ morality model is presented for further scientific testing.
THE ROAD IS MADE BY WALKING: AN INTRODUCTION
Authors: Bennett Pat , Teske John A. 
Published: August 2017

AbstractWe are living in a time of unprecedented challenges: human activity is now the primary driver shaping the planet and we are perilously close to breaching a variety of critical planetary boundaries—a prelude to the possible extinction of our species. How should we be thinking and acting—as persons, communities, institutions and societies—so as to best understand and respond to these challenges? What contribution can the field of science and religion make to develop the knowledge needed to negotiate the civilizational transition we face? Such questions were addressed through a series of dialogues at the 62nd annual conference of the Institute on Religion in an Age of Science in June of 2016—“How Can We Know? Co‐Creating Knowledge in Perilous Times.” This essay sets the background to these challenges and introduces the set of articles in this themed section.
A CONTRIBUTION TO THE DEBATE ON SCIENCE AND FAITH BY CHRISTIAN STUDENTS FROM ABIDJAN
Authors: Bom Klaas , van den Toren Benno 
Published: August 2017

AbstractThe science and faith debate is dominated by Western voices. In order to enrich this debate, the authors study the discourses of different groups of Christian academics and master's students in francophone Africa. This article describes the process of reconstructing and analyzing the discourse of a group of master's students from Abidjan (Ivory Coast) with the help of group model building and focus groups. Three characteristic features that emerge from this discourse include the foundational position of faith, the central role of truth, and the ambiguous connotations of the term “science” in this context. The reconstructed discourse is then brought into conversation with the North Atlantic debate, with a special focus on the concept of scientism.
Complete Genome Sequences of Mumps and Measles Virus Isolates from Three States in the United States
Authors: Magaña Laura C. , Espinosa Alex , Marine Rachel L. , Ng Terry Fei Fan , Castro Christina J. , Montmayeur Anna M. , Hacker Jill K. , Scott Samantha , Whyte Thomas , Bankamp Bettina , Oberste M. Steven , Rota Paul A. 
Published: August 2017

ABSTRACT
We report here the full coding sequence of nine paramyxovirus genomes, including two full-length mumps virus genomes (genotypes G and H) and seven measles virus genomes (genotypes B3 and D4, D8, and D9), from respiratory samples of patients from California, Virginia, and Alabama obtained between 2010 and 2014.
Draft Genome Sequences of Two Enterobacter cloacae subsp.
cloacae
Strains Isolated from Australian Hematology Patients with Bacteremia
Authors: Leong Lex E. X. , Shaw David , Papanicolas Lito , Lagana Diana , Bastian Ivan , Rogers Geraint B. 
Published: August 2017

ABSTRACT

Enterobacter cloacae
is a common member of the gut microbiota in healthy individuals. However, it is also an opportunistic pathogen, capable of causing bacteremia. We report the draft genomes of two
Enterobacter cloacae
subspecies
cloacae
strains isolated from hematology patients with bacteremia. Both isolates carry genes encoding extended-spectrum β-lactamases.
Complete Genome Sequence of a Hobi-Like Virus Isolated from a Nelore Cow with Gastroenteric Disease in the State of São Paulo, Brazil
Authors: Cortez Adriana , Araújo João Pessoa , Flores Eduardo Furtado , Ribeiro Márcio Garcia , Megid Jane , Paes Antonio Carlos , de Oliveira Filho José Paes , Ullmann Leila Sabrina , Malossi Camila Dantas , Heinemann Marcos Bryan 
Published: August 2017

ABSTRACT
The Hobi-like virus presents antigenic and molecular differences in relation to bovine virus diarrhea virus 1 and 2. The description of the complete genome of the Hobi-like virus SV757/15, isolated from a Nelore cow with gastroenteric disease in Brazil, will help in understanding the evolution and diversity of pestiviruses.
Genome Sequence of the Thermophilic Biomass-Degrading Fungus
Malbranchea cinnamomea
FCH 10.5
Authors: Granchi Zoraide , van Pelt Sake , Thanh Vu Nguyen , Olsson Lisbeth , Hüttner Silvia 
Published: August 2017

ABSTRACT

We report here the annotated draft genome sequence of the thermophilic biomass-degrading fungus
Malbranchea cinnamomea
strain FCH 10.5, isolated from compost at a waste treatment plant in Vietnam. The genome sequence contains 24.96 Mb with an overall GC content of 49.79% and comprises 9,437 protein-coding genes.
Draft Genome Sequence of
Sphingobacterium
sp. CZ-UAM, Isolated from a Methanotrophic Consortium
Authors: Steffani-Vallejo José Luis , Zuñiga Cristal , Cruz-Morales Pablo , Lozano Luis , Morales Marcia , Licona-Cassani Cuauhtemoc , Revah Sergio , Utrilla José 
Published: August 2017

ABSTRACT

Sphingobacterium
sp. CZ-UAM was isolated from a methanotrophic consortium in mineral medium using methane as the only carbon source. A draft genome of 5.84 Mb with a 40.77% G+C content is reported here. This genome sequence will allow the investigation of potential methanotrophy in this isolated strain.
Draft Genome Sequence of Aquitalea magnusonii Strain H3, a Plant Growth-Promoting Bacterium of Duckweed (
Lemna minor
)
Authors: Ishizawa Hidehiro , Kuroda Masashi , Ike Michihiko 
Published: August 2017

ABSTRACT

Aquitalea magnusonii
strain H3 is a promising plant growth-promoting bacterium for duckweed. Here, we report the draft genome sequence of strain H3 comprising 4,750,601 bp in 73 contigs. Several genes associated with plant root colonization were identified.
Draft Genome Sequence of the
d
-Xylose-Fermenting Yeast
Spathaspora xylofermentans
UFMG-HMD23.3
Authors: Lopes Daiane D. , Cibulski Samuel P. , Mayer Fabiana Q. , Siqueira Franciele M. , Rosa Carlos A. , Hector Ronald E. , Ayub Marco Antônio Z. 
Published: August 2017

ABSTRACT

Here, we report the draft genome sequence of the yeast
Spathaspora xylofermentans
UFMG-HMD23.3 (=CBS 12681), a
d
-xylose-fermenting yeast isolated from the Amazonian forest. The genome consists of 298 contigs, with a total size of 15.1 Mb, including the mitochondrial genome, and 5,948 predicted genes.
Complete Genome Sequence of Citrobacter freundii 705SK3, an OXA-48-Encoding Wastewater Isolate
Authors: Zurfluh Katrin , Stephan Roger , Klumpp Jochen , Nüesch-Inderbinen Magdalena , Hummerjohann Jörg , Bagutti Claudia , Marti Roger 
Published: August 2017

ABSTRACT

We present the genome sequence of
Citrobacter freundii
705SK3, a wastewater isolate harboring an IncL OXA-48-encoding plasmid. Assembly of the genome resulted in a 5,242,839-bp circular chromosome (GC content, 52%) and two closed plasmids of 296,175 bp and 63, 458 bp in size.
Nasal midazolam vs ketamine for neonatal intubation in the delivery room: a randomised trial
Authors: Milési Christophe , Baleine Julien , Mura Thibault , Benito-Castro Fernando , Ferragu Félicie , Thiriez Gérard , Thévenot Pierre , Combes Clémentine , Carbajal Ricardo , Cambonie Gilles 
Published: August 2017

ObjectiveTo compare the effectiveness of sedation by intranasal administration of midazolam (nMDZ) or ketamine (nKTM) for neonatal intubation.DesignA multicentre, prospective, randomised, double-blind study.SettingDelivery rooms at four tertiary perinatal centres in France.PatientsPreterm neonates with respiratory distress requiring non-emergent endotracheal intubation for surfactant instillation.InterventionsTreatment was randomly allocated, with each neonate receiving a bolus of 0.1 mL/kg in each nostril, corresponding to 0.2 mg/kg for nMDZ and 2 mg/kg for nKTM. The drug was repeated once 7 min later at the same dose if adequate sedation was not obtained.Main outcome measuresSuccess was defined by adequate sedation before intubation and adequate comfort during the procedure. Intubation features, respiratory and cardiovascular events were recorded.ResultsSixty newborns, with mean (SD) gestational age and birth weight of 28 (3) weeks and 1100 (350) g, were included within the first 20 min of life. nMDZ was associated with a higher success rate (89% vs 58%; RR: 1.54, 95% CI 1.12 to 2.12, p<0.01) and shorter delays between the first dose and intubation (10 (6) vs 16 (8) min, p<0.01).Number of attempts, time to intubation, mean arterial blood pressure measures over the first 12 hours after birth and length of invasive ventilation were not different.ConclusionsnMDZ was more efficient than nKTM to adequately sedate neonates requiring intubation in the delivery room. The haemodynamic and respiratory effects of both drugs were comparable.Clinical trialThis clinical trial was recorded on the National Library of Medicine registry (NCT01517828).
Nodes, paranodes and neuropathies
Authors: Fehmi Janev , Scherer Steven S , Willison Hugh J , Rinaldi Simon 
Published: August 2017

This review summarises recent evidence supporting the involvement of the specialised nodal and perinodal domains (the paranode and juxtaparanode) of myelinated axons in the pathology of acquired, inflammatory, peripheral neuropathies.The identification of new target antigens in the inflammatory neuropathies heralds a revolution in diagnosis, and has already begun to inform increasingly targeted and individualised therapies. Rapid progress in our basic understanding of the highly specialised nodal regions of peripheral nerves serves to strengthen the links between their unique microstructural identities, functions and pathologies. In this context, the detection of autoantibodies directed against nodal and perinodal targets is likely to be of increasing clinical importance. Antiganglioside antibodies have long been used in clinical practice as diagnostic serum biomarkers, and associate with specific clinical variants but not to the common forms of either acute or chronic demyelinating autoimmune neuropathy. It is now apparent that antibodies directed against several region-specific cell adhesion molecules, including neurofascin, contactin and contactin-associated protein, can be linked to phenotypically distinct peripheral neuropathies. Importantly, the immunological characteristics of these antibodies facilitate the prediction of treatment responsiveness.
Renal Denervation Suppresses Coronary Hyperconstricting Responses After Drug-Eluting Stent Implantation in Pigs In Vivo Through the Kidney–Brain–Heart Axis
Authors: Uzuka Hironori , Matsumoto Yasuharu , Nishimiya Kensuke , Ohyama Kazuma , Suzuki Hideaki , Amamizu Hirokazu , Morosawa Susumu , Hirano Michinori , Shindo Tomohiko , Kikuchi Yoku , Hao Kiyotaka , Shiroto Takashi , Ito Kenta , Takahashi Jun , Fukuda Koji , Miyata Satoshi , Funaki Yoshihito , Ishibashi-Ueda Hatsue , Yasuda Satoshi , Shimokawa Hiroaki 
Published: August 2017

Objective—
Drug-eluting stent–induced coronary hyperconstricting responses remain an important issue. The adventitia harbors a variety of components that potently modulate vascular tone, including sympathetic nerve fibers (SNF) and vasa vasorum. Catheter-based renal denervation (RDN) inhibits sympathetic nerve activity. We, thus, examined whether RDN suppresses drug-eluting stent–induced coronary hyperconstricting responses, and if so, what mechanisms are involved.

Approach and Results—

Protocol 1: pigs implanted with everolimus-eluting stents into the left coronary arteries underwent coronary angiography at 1 month after implantation for assessment of coronary vasomotion and adventitial SNF formation. Drug-eluting stent–induced coronary hyperconstricting responses were significantly enhanced associated with enhanced coronary adventitial SNF and vasa vasorum formation. Protocol 2: pigs implanted with everolimus-eluting stents were randomly assigned to the RDN or sham group. The RDN group underwent renal ablation. At 1 month, RDN significantly caused marked damage of the SNF at the renal arteries without any stenosis, thrombus, or dissections. Notably, RDN significantly upregulated the expression of α
2
-adrenergic receptor–binding sites in the nucleus tractus solitarius, attenuated muscle sympathetic nerve activity, and decreased systolic blood pressure and plasma renin activity. In addition, RDN attenuated coronary hyperconstricting responses to intracoronary serotonin at the proximal and distal stent edges associated with decreases in SNF and vasa vasorum formation, inflammatory cell infiltration, and Rho-kinase expression/activation. Furthermore, there were significant positive correlations between SNF and vasa vasorum and between SNF and coronary vasoconstricting responses.

Conclusions—
These results provide the first evidence that RDN ameliorates drug-eluting stent–induced coronary hyperconstricting responses in pigs in vivo through the kidney–brain–heart axis.
CloudSat and CALIPSO within the A-Train: Ten Years of Actively Observing the Earth System
Authors: Stephens Graeme , Winker David , Pelon Jacques , Trepte Charles , Vane Deborah , Yuhas Cheryl , L’Ecuyer Tristan , Lebsock Matthew 
Published: August 2017

Abstract
One of the most successful demonstrations of an integrated approach to observe Earth from multiple perspectives is the A-Train satellite constellation. The science enabled by this constellation flourished with the introduction of the two active sensors carried by the National Aeronautics and Space Administration (NASA) CloudSat and the NASA–Centre National d’Études Spatiales (CNES) Cloud–Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) satellites that were launched together on 28 April 2006. These two missions have provided a 10-yr demonstration of coordinated formation flying that made it possible to develop integrated products and that offered new insights into key atmospheric processes. The progress achieved over this decade of observations, summarized in this paper, clearly demonstrate the fundamental importance of the vertical structure of clouds and aerosol for understanding the influences of the larger-scale atmospheric circulation on aerosol, the hydrological cycle, the cloud-scale physics, and the formation of the major storm systems of Earth. The research also underscored inherent ambiguities in radiance data in describing cloud properties and how these active systems have greatly enhanced passive observation. It is now clear that monitoring the vertical structure of clouds and aerosol is essential, and a climate data record is now being constructed. These pioneering efforts are to be continued with the Earth Clouds, Aerosol and Radiation Explorer (EarthCARE) mission planned for launch in 2019.
Natural Bioactive Food Components for Improving Enteral Tube Feeding Tolerance in Adult Patient Populations
Authors: Kuchnia Adam J. , Conlon Beth , Greenberg Norman 
Published: August 2017

AbstractTube feeding (TF) is the most common form of nutrition support. In recent years, TF administration has increased among patient populations within and outside hospital settings, in part due to greater insurance coverage, reduced use of parenteral nutrition, and improved formularies suitable for sole source nutrition. With increasing life expectancy and improved access to TFs, the number of adults dependent on enteral nutrition is expected to grow. However, enteral TF intolerance (ETFI) is the most common complication of TFs, typically presenting with at least 1 adverse gastrointestinal event, including nausea, diarrhea, and constipation. ETFI often leads to reductions in TF volume with associated energy and protein deficits. Potentially ensuing malnutrition is a major public health concern due its effects on increased risk of morbidity and mortality, infections, prolonged hospital length of stay, and higher healthcare costs. As such, there is a need for intervention strategies to prevent and reduce ETFI. Incorporating whole foods with bioactive properties is a promising strategy. Emerging research has elucidated bioactive properties of whole foods with specific benefits for the prevention and management of adverse gastrointestinal events commonly associated with TFs. However, lack of evidence‐based recommendations and technological challenges have limited the use of such foods in commercial TF formulas. This review addresses research gaps by discussing 5 whole foods (rhubarb, banana, curcumin, peppermint oil, and ginger) with bioactive attributes identified through literature searches and clinical experience as having substantial scientific rationale to consider their application for ETFI in adult populations.
Comparison of Clevidipine and Nicardipine for Acute Blood Pressure Reduction in Patients With Stroke
Authors: Allison Teresa A. , Bowman Stephanie , Gulbis Brian , Hartman Heather , Schepcoff Sara , Lee Kiwon 
Published: August 2017

Objective: The aim of this study was to determine whether clevidipine (CLEV) achieved faster blood pressure control compared to nicardipine (NIC) in patients presenting with either an acute ischemic stroke (AIS) or a spontaneous intracerebral hemorrhage (ICH). Methods: This was a retrospective, observational, cohort study conducted in patients with AIS or ICH admitted to the emergency department of a Comprehensive Stroke Center from November 2011 to June 2013 who received CLEV or NIC continuous infusion for acute blood pressure management. Results: The study included 210 patients: 70 in the CLEV group and 140 in the NIC group. There was no difference in mean time (standard deviation [SD]) from initiation of the infusion to goal systolic blood pressure (SBP), CLEV: 50 (83) minutes versus NIC: 74 (103) minutes, P = .101. Comparison of the 2 agents within diagnosis showed no difference. Hypotension developed in 5 (7.1%) CLEV patients versus 14 (10%) NIC patients ( P = .003). There was no difference in the percentage change at 2 hours; CLEV: −20% (16%) versus NIC: −16% (16%), P = .058. Mean (SD) time to alteplase administration from admission was 56 (22) minutes in the CLEV group versus 59 (25) minutes in the NIC group ( P = .684). Conclusions: There was no difference in the mean time from initiation of the infusion to the SBP goal between agents or in the secondary outcomes. Due to the lack of differences observed, each agent should be considered based on the patient care needs of the institution.
Sepsis at a Safety Net Hospital: Risk Factors Associated With 30-Day Readmission
Authors: Weinreich Mark A. , Styrvoky Kim , Chang Shelley , Girod Carlos E. , Ruggiero Rosechelle 
Published: August 2017

Background: Sepsis is a leading cause of hospitalization, and subsequent readmissions are frequent and costly. There is an expanding body of literature describing risk factors for readmissions in patients with sepsis. However, there are little data studying medically underserved patients who typically receive their care at a safety net hospital. Methods: In a retrospective cohort study, we evaluated 1355 sepsis survivors at risk of hospital readmission in fiscal year 2013 at a safety net hospital. We described patient characteristics during their initial and readmission hospitalizations and analyzed risk factors associated with 30-day readmission. Results: The 30-day readmission rate among sepsis survivors was 22.6%. Comorbid conditions associated with readmissions included end-stage renal disease (odds ratio [OR], 1.26; 95% confidence interval [CI], 1.17-1.36), malignancy (OR, 1.14; 95% CI, 1.08-1.21), and cirrhosis (OR, 1.11; 95% CI, 1.02-1.20). Bacteremia during the initial hospitalization (OR, 1.07; 95% CI, 1.01-1.15) and being discharged with a vascular catheter (OR, 1.10; 95% CI, 1.01-1.20) were associated with readmission. Less severe sepsis during the initial hospitalization was associated with a reduced risk of 30-day readmission (OR, 0.91; 95% CI, 0.87-0.94). Conclusions: At a safety net hospital, patients who survived their initial sepsis hospitalization had a 30-day readmission rate to our institution of 22.6% that is comparable to rates described in prior studies. Readmission was commonly due to infection. Factors associated with readmission included multiple comorbid medical conditions, bacteremia, and being discharged with a vascular catheter. Further studies in this population are needed to determine potential modifiability of these risk factors in an attempt to reduce sepsis readmissions.
The Association Between Pregnancy Intention and Breastfeeding
Authors: Keddem Shimrit , Frasso Rosemary , Dichter Melissa , Hanlon Alexandra 
Published: August 2017

Background: Although breastfeeding is associated with proven benefits to both mother and child, there are many factors that influence a mother’s decision to breastfeed. Pregnancy intentionality at the time of conception is associated with postpartum maternal behavior including breastfeeding. Research aim: We sought to understand how maternal and paternal pregnancy intentions were associated with breastfeeding initiation and duration in a nationally representative sample. Methods: We used a cross-sectional, retrospective study of the CDC National Survey of Family Growth data to examine the link between pregnancy intentionality and breastfeeding initiation and duration among women ages 15 to 44 years. Results: We found that whereas the mother’s intention to have a child was a factor in how long she breastfed, the paternal intention to have a child predicted whether the mother breastfed at all. Additionally, Hispanic mothers were most likely to breastfeed and breastfed the longest of any other group. Age and education were also positive predictors of ever breastfeeding. Conclusion: Understanding the father’s and mother’s attitudes toward the pregnancy and influence on breastfeeding intention is important for intervention planning.