bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluasi penggunaan rekam medis elektronik di rumah sakit: Studi kasus di Rumah Sakit Wahidin Sudiro Husodo Mojokerto
Authors: Siswanto Sheila Aprilia , Nisak Umi Khoirun 
Published: September 2024

Background: Evaluation of the use of medical records is very important. The Mandatory Use of Software Technologies (MMUST) model was created to address this problem focusing exclusively on the environment. Various studies have been conducted with MMUST as a theoretical basis. MMUST has 8 variables which include: system quality, information quality, performance expectancy, social influence, attitude, overall satisfaction, and net benefits.Objectives: This study aims to assess the use of Electronic Medical Records at the Regional General Hospital Wahidin Sudiro Husodo Mojokerto using the Model For Mandatory Use Of Software Technologies and then sharing suggestions or guidelines to increase the use of electronic medical records.Methods: This study used quantitative analytics. The study population was all employees and the study sample was doctors and nurses who were randomly taken in proportion estimation. The sample size is 100. The study was conducted in January 2024 at Wahidin Sudiro Husodo Hospital Mojokerto. Data were collected through questionnaires and in-depth interviews and analyzed using linear regression.Results: The results of the analysis show that Information Quality (IQ) influences Information Satisfaction (IS) (p=0,000). This means that health workers at the DR Regional General Hospital. Wahidin Sudiro Husodo Mojokerto agrees that quality data can be obtained from Electronic Medical Records. But in reality, the use of Electronic Medical Records at the DR Regional General Hospital. Wahidin Sudiro Husodo Mojokerto is still low.Conclusion: Use of Electronic Medical Records in DR General Hospital. Wahidin Sudiro Husodo Mojokerto is still low because respondents stated that many information components have not been accommodated by Electronic Medical Records.
AWARENESS ABOUT COVID-19 AND ITS VARIANTS AMONG AFGHANISTANI POPULATION- A RETROSPECTIVE STUDY
Authors: Forqani Mohammad Sharif , Sabawoon Mohammad Naser , Sharif Muhammad Shafi 
Published: September 2024

Introduction: Corona virus caused COVID-19 is an unusual, highly contagious infectious disease caused by recently identified severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a clinical threat and presented a major health crisis worldwide in the absence of a specific vaccine or antiviral drugs. Its severity increases due to its rapidly mutating genotype.
Aim: This study is retrospective analysis awareness in Afghanistani population about COVID-19 and its different variants.
Material and Methods: For obtaining data a questionnaire on general knowledge about COVID-19 and its variants was prepared and distributed among the various classes of population in Afghanistan. The questions like the name, age, sex, education, province, COVID-19 vaccination status and some basic questions about COVID-19 and its variants etc were included to obtain their responses. Questionnaire was prepared in both English and Afghani language to penetrate the population knowledge. The data thus obtained was analyzed using basic statistical techniques for proper understanding of different aspects of awareness.
Results and Discussion: Study reported that educated population of Afghanistan especially medical, nursing, pharmacy and other healthcare sectors were found to be well aware with COVID-19, its causes and prevention. Large educated pool of population about 41.5% did not received even a single shot of Covid vaccine the unusual reasons were God will save them, lack of time, money and more than 10% won’t believe in Covid. Prominent anti Covid vaccines administered to Afghanistani population were Covaxin, Covishield, and Johnson & Johnson. Good thing is that with the technological advancements and internet facilities most of the population possesses basic knowledge about COVID-19.
Conclusion: Since a significant large population did not receive even single shot of COVID-19 vaccination, this is an alarming situation because Corona is a rapidly mutating virus and its virulence will pose serious threats to mankind in future. Extensive study is required to find out the root cause of public negligence.
A STUDY ON PRESCRIBING PATTERNS OF ANTI-DIABETIC DRUGS IN TYPE 2 DIABETIC PATIENTS
Authors: Gunda Raghavendra Kumar , Ram N Kodanda 
Published: September 2024

Objective: The main objective of the study is to assess the prescribing patterns of antidiabetic drugs in type 2 diabetic patients.
Methodology: A prospective observational study was conducted in Department of Endocrinology in Sri Care Hospitals, Narasaraopet for a period of 6 months. Patient of both genders who were diagnosed with diabetes were included in the study.
Results: A total of 150 patients were recruited for the study, 53.34% of the patients were males and 46.66% of the patients were females. Most of the patients were in the age group of 50-59 years i.e 28.6%. This study also revealed the common predominant comorbid condition of 30% with diabetes mellitus. In this study different therapy observed for monotherapy is Insulin in 21 (46.67%), dual therapy is Metformin & Glimepiride in 32 (46.38%), and triple therapy is Metformin + Glimepiride + Voglibose in 22 (61.12%) patients.
Conclusion: This study concludes that prescriptions were rational. Current investigation focussed on rational choice of drug based on demographic data, associated conditions and complications would give additional insights into prescribing patterns in diabetes mellitus
Mitigasi Bencana Berbasis Kearifan Lokal Di Desa Kaidundu Barat Kabupaten Bone Bolango
Authors: Eraku Sunarty Suly , Baruadi Moh. Karmin 
Published: September 2024

Kaidundu Barat Village is structurally part of Bulawa Sub-district, geographically West Kaidundu Village is located between Pinomontiga village in Bulawa Sub-district. The topographic conditions of Kaidundu Barat Village are located in hilly/highland areas and some lowlands and coastal areas. Kaidundu Barat Village was also affected by landslides which resulted in damaged houses, although there were no casualties but it is estimated to have a very large loss. Therefore, it is necessary to socialize and educate local wisdom-based disaster mitigation to the community who mostly live in the area to socialize disaster mitigation so that in this case the surrounding community can be aware of disasters arising from the coastal area of Kaidundu Barat Village in Bulawa District. The main objective of this activity is to socialize and educate local wisdom-based disaster mitigation. This activity was carried out through the method of material presentation and questions and answers about how to act in the face of disasters, local wisdom-based disaster mitigation and landslide disaster mitigation and environmental conservation are very important to protect the community and the environment from the negative impacts of disasters. Based on the results of community service in the seminar activities, it shows that the participants, namely the people of Kaidundu Barat village, are very enthusiastic and satisfied with this activity. Local wisdom-based disaster mitigation has the potential to improve community preparedness and response to disasters by utilizing local knowledge and culture. Local wisdom-based disaster mitigation must involve the active role of the community in the planning process, decision-making, and implementation of mitigation measures. This seminar activity improved the community's understanding of risk and provided a sense of ownership of mitigation measures. Future development of this activity program should involve disaster mitigation education in the school curriculum or extension programs to increase understanding and awareness about disaster.
Efektifitas Lilin Aromaterapi Serbuk Daun Cengkeh Terhadap Kematian Nyamuk Aedes aegypti
Authors: Mustafa Mustafa , Muhlisa Muhlisa , Arba Susan , Irwan Ristyanisari 
Published: September 2024

Latar Belakang: Demam berdarah adalah infeksi virus yang dibawa nyamuk Aedes aegypti yangmenyebabkan penyakit mirip flu yang parah dan, terkadang menyebabkan komplikasi yang berpotensimematikan yang disebut demam berdarah. Pemberantasan nyamuk bisa memanfaatkan berbagaitumbuhan yang ada di sekitar mayarakat. Tujuan Penelitian: untuk mengetahui efektivitas lilinaromaterapy serbuk daun cengkeh terhadap kematian nyamuk Aedes aegypti. Metode: Penelitian inimenggunakan penelitian eksperimental dengan metode post test only group control design. Sampelnyamuk yang digunakan adalah nyamuk Aedes Sp betina yang sudah dewasa. Jumlah sampel nyamukyang digunakan sebanyak 150 ekor. Percobaan penelitian dilakukan sebanyak 3 kali denganmelakukan pengamatan selama 12 jam. Pengamatan dimulai pada pukul 09.00 – 21.00. Hasil: padapenelitian percobaan pertama jumlah kematian nyamuk 100%, percobaan kedua 76% dan percobaanketiga 56 %. Sedangkan pada kontrol (lilin tanpa campuran serbuk daun cengkeh) tidak didapatkanadanya kematian nyamuk pada percobaan satu sampai dengan percobaan ketiga. Suhu rata-rata padapenelitian ini yaitu 30,1oC dan kelembaban 74%. Kesimpulan: Lilin aroamterapy serbuk daun cengkeh memiliki efektifitas terhadap kematian nyamuk Aedes aegypti
Perbandingan Kualitas Kompos Ampas Tahu Dengan Serbuk Kayu Mengunakan Media Takakura
Authors: Purwiningsih Dwi Wahyu 
Published: September 2024

Latar Belakang: Menurut WHO, sampah adalah barang yang berasal dari kegiatan manusia yangtidak lagi digunakan, tidak dipakai dan tidak disenangi.Solusi penanganan sampah yang dapat digunakan dengan proses pengomposan. Kompos adalah pupuk yang berasal dari proses pelapukanbahan yang berupa kotoran hewan, dan sampah organik. limbah ampas tahu sebagai kompos denganpenambahan EM4 sebagai aktivator. Dengan tambahan Serbuk kayu yang dihasilkan dari prosespenggergajian.Takakura adalah alat pengomposan sampah organik Tujuan Penelitian: tujuanpenilitian adalah untuk mengetahui kualitas kompos ampas tahu dengan serbuk kayu mengunakanmedia takakura. Metode: jenis penilitian ini Eksperimen. Lokasi penelitian di kampus B programstudi D-III Sanitasi Poltekkes Kemenkes Ternate. Populasi dan sampel dalam penelitian ini adalahsampah organik sebanyak 40kg, kemudian ampas tahu 20 kg dengan serbuk kayu 20 kg. Hasil: Hasilpenelitian menunjukkan bahwa nilai ampas tahu sudah memenuhi syarat SNI 2803:2010 dengan nilai suhu yaitu 32oC pH yaitu 7,5 dan kelembaban 60% serta serbuk kayu juga sudah memenuhi syaratSNI 2803:2010 dengan nilai suhu yaitu 30o C, pH yaitu 7,5 dan kelembaban 40%. Waktu pengomposan ampas tahu selama 20 hari dengan jumlah kompos sebanyak 5 ons dan serbuk kayumemiliki waktu pengomposan selama 20 hari dengan jumlah kompos 2 kg. Kesimpulan: Kualitaskompos baik dari serbuk kayu maupun ampas tahu sudah menunujukkan kualitas yang memenuhisyarat.
Sparta and Euripides’ Electra
Authors: Beer David George 
Published: September 2024

From early on the myths of Agamemnon and Orestes had political overtones. In the Iliad it is Agamemnon as king of Mycenae who leads the Argive forces against Troy but, just as early, Agamemnon and Orestes seem to have been closely associated with Laconia. This article provides a political interpretation of Euripides’ Electra in which I argue that Electra is an anti-Spartan tragedy arising from Sparta’s desire to control Argos. Although the mythological background is the Trojan War, the tragedy reflects the deleterious effects of the Peloponnesian War. Unlike in Aeschylus’ Oresteia and Sophocles’ Electra where the curse on the royal house forms the central background, the larger focus in Euripides’ tragedy is on the territory of Argos. This point is clearly suggested by having the skene depict a farmer’s hut which, situated somewhere in the mountains, is emblematic of Argive territory. Argos is a polis divided between two hostile parties: Orestes and Electra, the legitimate successors of the former Argive king, Agamemnon, and pro-Spartan usurpers, the Tyndarids, represented in the play by Clytemnestra and supported in the epilogue by her Tyndarid brothers, the Dioscuri. Castor, their spokesman, provides a completely unsatisfactory moral solution to the revenge of Orestes and Electra, a solution that is simply designed to serve Spartan interests. By imposing a life-long exile on Agamemnon’s children, his legal heirs, Castor leaves Argos open for the Spartans to take control. The tragedy contrasts a heroic past with a sordid present which accounts for the so called ‘Low Style’ of Electra. I shall suggest a date between 421–417 BC for the play’s production, when there was an insecure peace between Athens and Sparta and the politics of Argos assumed much importance.
Evaluating cells metabolic activity of bioinks for bioprinting: the role of cell-laden hydrogels and 3D printing on cell survival
Authors: Mazzoldi Elena Laura , Gaudenzi Giulia , Ginestra Paola Serena , Ceretti Elisabetta , Giliani Silvia Clara 
Published: September 2024

IntroductionTissue engineering has advanced significantly in recent years, owing primarily to additive manufacturing technology and the combination of biomaterials and cells known as 3D cell printing or Bioprinting. Nonetheless, various obstacles remain developing adequate 3D printed structures for biomedical applications, including bioinks optimization to meet biocompatibility and printability standards. Hydrogels are among the most intriguing bioinks because they mimic the natural extracellular matrix found in connective tissues and can create a highly hydrated environment that promotes cell attachment and proliferation; however, their mechanical properties are weak and difficult to control, making it difficult to print a proper 3D structure.MethodsIn this research, hydrogels based on Alginate and Gelatin are tested to evaluate the metabolic activity, going beyond the qualitative evaluation of cell viability. The easy-to-make hydrogel has been chosen due to the osmotic requirements of the cells for their metabolism, and the possibility to combine temperature and chemical crosslinking. Different compositions (%w/v) are tested (8% gel-7% alg, 4% gel-4% alg, 4% gel-2% alg), in order to obtain a 3D structure up to 10.3 ± 1.4 mm.ResultsThe goal of this paper is to validate the obtained cell-laden 3D structures in terms of cell metabolic activity up to 7 days, further highlighting the difference between printed and not printed cell-laden hydrogels. To this end, MS5 cells viability is determined by implementing the live/dead staining with the analysis of the cellular metabolic activity through ATP assay, enhancing the evaluation of the actual cells activity over cells number.DiscussionThe results of the two tests are not always comparable, indicating that they are not interchangeable but provide complementary pieces of information.
A pig model exploring the postnatal hair follicle cycle
Authors: Li Shujuan , Zou Quan , Jiang Yao , Wang Yi , Ding Xiangdong 
Published: September 2024

IntroductionThe hair follicle (HF) is a micro-organ capable of regeneration. A HF cycle consists of an anagen, catagen and telogen. Abnormalities in the HF cycle can lead to many hair disorders such as hair loss. The pig is a good biomedical model, but there are few data on their HF cycle. The aim of this study was to classify the pig HF cycle and determine the feasibility of the pig as an animal model for human HF cycle.MethodsSkin samples from 10 different postnatal (P) days Yorkshire pigs was collected to determine the key time points of the first HF cycle in pig by H&amp;E staining, immunofluorescence staining, q-PCR and western-blot.ResultsBy morphological observation and detection of markers at different stages, pig HF cycle was classified into three main periods - the first anagen until P45, catagen (P45–P85), telogen (P85–P100), and next anagen (&gt;P100). In addition, we examined the expression of important genes AE15, CD34, Versican, Ki67 et al. related to the HF cycle at different stages of pig HF, indicating that pig and human share similarities in morphology and marker gene expression patterns of HF cycle.DiscussionOur findings will facilitate the study of HF cycle and offer researchers a suitable model for human hair research.
Fabrication and characterization of hybrid thermoelectric materials based on aligned nanowires
Authors: Lee Min-Jeong , Kim Chae Yoon , Lim Jae-Hong 
Published: September 2024

This study introduces the synthesis of a hybrid thermoelectric material with enhanced conductivity and a high Seebeck coefficient, leveraging the properties of Te nanowires (NWs) and the conductive polymer PEDOT:PSS. Te NWs were synthesized using the galvanic displacement reaction. To further enhance conductivity, Ag-Te NWs were synthesized under optimized conditions via the Ag topotactic reaction, achieving desired results within 7 min using ethylene glycol and AgNO3. This hybrid material exhibited an electrical conductivity of 463 S/cm, a Seebeck coefficient of 69.5 μV/K at 300 K, and a power factor of 260 μW/mK2. These metrics surpassed those of conventional Te/PEDOT:PSS hybrids by a factor of 3.6, highlighting the superior performance of our approach. This study represents a significant advancement in thermoelectric materials, improving both conductivity and efficiency.
Predictive value of neutrophil to lymphocyte ratio for clinical outcome in patients with atrial fibrillation: a systematic review and meta-analysis
Authors: Peng Lei , Liu Li , Chai Miaomiao , Cai Zhonggui , Wang Deqi 
Published: September 2024

BackgroundThe association between the Neutrophil-to-Lymphocyte Ratio (NLR) and the prognosis of Atrial Fibrillation (AF) has been extensively studied, yet clinical outcomes have varied. Consequently, this analysis was undertaken to explore the link between NLR and the prognostic markers of AF.MethodsWe conducted an exhaustive search across electronic databases, including PubMed, Embase, Web of Science, and the Cochrane Library, to investigate the correlation between the NLR and indicators of adverse clinical outcomes associated with AF from the database establishment date through March 31, 2024. In this study, the recurrence rate of AF was the primary outcome measure, while the secondary outcome measures were mortality, stroke, and left atrial thrombus. Odds ratio (OR), relative risk (RR), hazard ratio (HR) and standard mean difference (SMD) with a 95% confidence interval (CI) were integrated for assessment, and the stability of prognostic outcomes and publication bias were verified by sensitivity analysis and Egger's test, respectively. Subgroup analyses were performed to pinpoint the sources of heterogeneity.ResultsThis analysis included 20 studies, encompassing a total of 59,256 patients. Our statistical analysis of both categorical and continuous variables revealed that an elevated NLR was significantly associated with increased risks in AF patients for recurrence (categorical variable: OR = 1.39, 95% CI = 1.21–1.60; continuous variable: SMD = 0.49, 95% CI = 0.24–0.74), mortality (categorical variable: OR = 1.87, 95% CI = 1.59–2.20), stroke (categorical variable: OR = 1.56, 95% CI = 1.13–2.17; continuous variable: SMD = 0.77, 95% CI = 0.63–0.91), and left atrial thrombus (categorical variable: OR = 1.87, 95% CI = 1.27–2.75; continuous variable: SMD = 0.59, 95% CI = 0.30–0.89). Subgroup analyses found that high NLR was significantly linked to AF recurrence when the NLR was &gt;3. High NLR was significantly linked to the risk of stroke in AF when the NLR was ≤3.ConclusionsThis study suggested that a high NLR is significantly linked to prognostic risk markers of AF, and NLR may be an effective biomarker for the prognosis of AF in clinical practice.Systematic Review RegistrationPROSPERO (CRD42024530970).
Serum high sensitive C-reactive protein level and its correlation with lipid profile among dyspeptic patients with or without Helicobacter pylori infection in East Gojjam zone, Ethiopia
Authors: Baye Gelagey , Wondmneh Bayu , Ashenef Baye , Jemal Mohammed , Baylie Temesgen 
Published: September 2024

IntroductionDyspepsia is a group of symptoms located in the gastroduodenal area of the upper gastrointestinal tract characterized by epigastric pain, postprandial completeness, or early satiety and occasionally related to heartburn. Helicobacter pylori is the major causative agent of dyspepsia and gastric-related disorders; besides, it alters different metabolic processes in the human body, such as lipid metabolism and inflammatory processes. Even though dyslipidemia and inflammation are independent risk factors for cardiovascular disorders, we are assessing the interaction between serum lipids and highly sensitive C reactive protein levels among dyspeptic patients to predict potential cardiovascular disorders.ObjectivesTo assess serum high sensitive C reactive protein levels and its correlation with lipid profile among dyspeptic patients.MethodsA hospital-based comparative cross-sectional study was conducted from May 2022 to March 2023 in East Gojjam, Ethiopia. One hundred Helicobacter pylori-positive and 100 Helicobacter pylori-negative dyspeptic patients were included. Data were checked for completeness and entered into SPSS version 26.0 software and analyzed. The association between variables was determined by Pearson correlation analysis. A p-value &lt;0.05 was considered statistically significant.ResultThe mean serum high sensitive C reactive protein was 8.09 ± 7.84 mg/L, and serum high-density lipoprotein, low-density lipoprotein, total cholesterol, and triglyceride were (35.35 ± 7.5, 105.07 ± 87.63, 142.31 ± 71.31, 160.07 ± 43.06) mg/dl, respectively, for Helicobacter pylori positive dyspeptic patients. Among these values, high-density lipoprotein is negatively correlated with high sensitive C reactive and total cholesterol is positively correlated with high sensitive C reactive levels among Helicobacter pylori-infected dyspeptic patients with a p-value &lt; 0.05, but in Helicobacter pylori negative dyspeptic patients, there is no significant correlation between lipid profile and high sensitive C reactive levels.ConclusionSerum high sensitive C reactive levels had a negative correlation with high-density lipoprotein and a positive correlation with total cholesterol among Helicobacter pylori-positive dyspeptic patients. Therefore, the significant interaction between serum lipid levels and inflammation exacerbates the potential risk of cardiovascular disorders among Helicobacter pylori-positive dyspeptic patients.