bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Dynamics of Family Financial Socialization: Impact on Financial Self-efficacy and Financial Behavior
Authors: Kaur Rajwinder , Singh Manjit 
Published: September 2024

Purpose: The objectives of the study include examining the role of family financial socialization (FFS) in shaping young adults’ financial self-efficacy (FSE), understanding how FSE contributes to financial behavior (FB), and exploring the mediating role of FSE in the relationship between FFS and FB of young adults. Design/Methodology: Using a quantitative technique, data were collected from 395 university students in Punjab, India. The study utilized partial least squares structural equation modeling (PLS-SEM) to scrutinize and decipher the intricate interconnections among the variables. Findings: The results support the hypotheses, demonstrating the significant influence of FFS on FSE and FB, as well as the mediating role of FSE. Practical/Social Implications: Educational institutions and policymakers can integrate these findings into financial education programs to boost financial literacy and self-efficacy among young adults. Additionally, policymakers can encourage parents to actively engage in open financial discussions with their children. Originality/Value: This study broadens the scope of existing research by investigating FFS through multiple dimensions and focusing on university students in Punjab, a previously underexplored demographic. It also uniquely examines the mediating role of FSE in the relationship between FFS and FB.
Exploring the Landscape of Polymerase Chain Reaction in Indian Medical Research: A Scientometric Analysis
Authors: Hazarika Rima , Sudhier K. G. 
Published: September 2024

Background and Aims: The polymerase chain reaction (PCR) has revolutionised medical research in India by offering a rapid and precise method for amplifying deoxyribonucleic acid (DNA) sequences crucial for various applications in healthcare. It aims to investigate publication growth, leading authors, productive journals, collaborating countries, keywords, institutional affiliations and funding agencies involved in PCR-related research within India. Methodology: A scientometric analysis assessed India’s PCR research performance using 10,509 articles from Scopus (2013-2022). Biblioshiny and VOSviewer aided data analysis, while Microsoft Excel facilitated computations. Results: The finding reveals the continuous growth in PCR publications, with significant contributions from researchers like Aman Sharma from the Post Graduate Institute of Medical Education and Research (Chandigarh) and journals like the Indian Journal of Medical Microbiology. Notable contributors hail from the All India Institute of Medical Sciences (AIIMS), New Delhi. International collaborations, especially with the United States, underscore the global outreach of PCR research in India. Keyword analysis reveals emerging trends and research themes in PCR, reflecting its evolving role in addressing contemporary health challenges. Funding agencies such as the Indian Council of Medical Research and the Ministry of Science and Technology, India (DBT) are crucial in supporting PCR research endeavours. Conclusions: This study provides valuable insights into the dynamics of PCR research in India, highlighting areas for future investigation and collaboration to further advance medical research and healthcare outcomes.
Efficacy of ultrasonography and color-Doppler for early prediction of hemodialysis arteriovenous fistula unassisted maturation
Authors: Chaudhary Shailendra K , Dikshit Nitin Arun , Yadu Neha , Parihar Anit , Kohli Neera , Dwivedi Durgesh Kumar 
Published: September 2024

Background: Arteriovenous fistula (AVF) failure is a prevalent concern for patients with end-stage kidney disease on hemodialysis. Recognizing the efficacy of ultrasound Doppler in post-operative AVF evaluation, this study sought to discern the predictive capabilities of various ultrasonographic and color-Doppler metrics for early AVF outcomes. Methods: This single-center, prospective cohort study spanned 1 year and, post ethical clearance, included all patients who underwent native AVF creation surgery and were subsequently referred for standard post-operative ultrasound Doppler assessment. Parameters such as fistula size, cephalic vein area and diameter, and AVF flow velocity and rates were assessed on post-operative day 2, week 2, and week 6. These initial findings were juxtaposed with later outcomes to determine unassisted AVF results. Results: Of the initial cohort of 40 patients, 75% encountered AVF failure, whereas 25% realized successful unassisted AVF maturation. A notable observation was the significant variance in AVF flow rates as early as post-operative day 2. A threshold of >246 ml/min was indicative of successful unassisted AVF maturation, leading to a sensitivity of 80% and a specificity of 70%. Although the cephalic vein diameter on post-operative day 2 lacked a robust association with AVF outcomes, a cut-off of >3.4 mm, when combined with flow rate testing, augmented the cumulative sensitivity to 92%. Conclusion: Ultrasound Doppler stands out as a valuable quantitative imaging modality, adept at prognosticating AVF outcomes from as early as post-operative day 2. In particular, a flow rate exceeding 246 ml/min and a cephalic vein diameter surpassing 3.4 mm are salient indicators for the early prediction of successful AVF outcomes.
Continuing the conversation about echolalia and gestalt language development: A response to Haydock, Harrison, Baldwin, and Leadbitter
Authors: Venker Courtney E , Lorang Emily 
Published: September 2024

Although gestalt language development incorporates some neurodiversity-affirmative strategies (e.g. embracing echolalia), it is also associated with numerous ideas, assertions, and clinical strategies that lack theoretical and empirical support. For this reason, we believe it is premature to embrace gestalt language development as a neurodiversity-affirmative practice. Given the potential for miscommunication, we must strive for clarity and precision in our terminology (e.g. making a clear distinction between delayed echolalia and the broader set of ideas that comprise gestalt language development). The field of autism will benefit from in-depth discussions about the relationship between neurodiversity-affirmative practices and evidence-based practices. Lay Abstract It was recently suggested that a set of ideas known as gestalt language development be embraced as a neurodiversity-affirmative practice. Neurodiversity refers to the idea that people interact with the world in many different ways and that there is not a single right way to do so. Some aspects of gestalt language development, such as embracing autistic communication, are consistent with neurodiversity. However, gestalt language development is also associated with numerous ideas, assertions, and clinical strategies that lack theoretical and empirical support. For this reason, we believe it is premature to embrace gestalt language development as a neurodiversity-affirmative practice. We propose that it is important to make sure we use language that differentiates between delayed echolalia and the broader set of ideas that comprise gestalt language development. We also suggest that it is important to discuss the relationship between neurodiversity-affirmative practices and practices supported by research evidence.
Canadian Real-World Study Long-Term Clinical Results Using Dupilumab for Chronic Rhinosinusitis With Polyps
Authors: Kilty Shaun J. , Lasso Andrea 
Published: September 2024

Background Dupilumab, an anti-IL4 receptor-α monoclonal antibody, was the first biologic to be approved in Canada for the treatment of Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). In phase III clinical trials, it has demonstrated to be effective in reducing nasal polyp size and the severity of symptoms, improve disease-specific quality of life, and to have an acceptable safety profile. This study aims to present long-term follow-up data on disease-specific sinonasal outcomes of patients with CRSwNP who have been treated with dupilumab for up to 3 years in a real-world setting. Methods Retrospective review of electronic medical records of a single Canadian rhinology center evaluating disease-specific sinonasal outcomes that are routinely collected for clinical care. This study included all patients who received dupilumab for the treatment of CRSwNP and who had completed at least one follow-up visit. The Sino-Nasal Outcome Test (SNOT)-22 was used to evaluate treatment symptom improvement. Results Ninety-nine patients started dupilumab therapy during the study period. The mean SNOT-22 at the start of therapy was 61.1 (±22.91) At the time of the review, 65 patients had completed 1 year of therapy, 40 had completed 2 years of therapy, and 18 had completed 3 years of therapy. The mean SNOT-22 score at these timepoints was 16.75 (±13.86), 15.02 (±14.40), and 10.22 (±11.56), respectively. Conclusion This real-world study shows that in patients with CRSwNP treated with dupilumab, improvement in disease-specific quality of life seen after 1 year continues and can be maintained at 3 years of treatment.
Three-Year Outcomes After Posterior Nasal Neurectomy in Perennial Moderate and Severe Allergic Rhinitis Patients
Authors: Zhang Bin , Wang Jiayan , Wang Wei , Xu Ting , Jia Xujing , Chen Manman , Xu Ming 
Published: September 2024

Background Posterior nasal neurectomy (PNN) has been shown to reduce the symptom burden of patients with perennial moderate and severe allergic rhinitis (AR). Objectives To evaluate the long-term safety and effectiveness of PNN for the treatment of perennial moderate and severe AR. Methods A prospective 3-year single-arm study was conducted in which the reflective total nasal symptom score (rTNSS) and total non-nasal symptom score (rTNNSS) were collected preoperatively and at 3 months, 6 months, 1 year, 2 years, and 3 years postoperatively. Results A total of 213 patients with AR were recruited and received PNN, of whom 154 patients completed the 3-year follow-up. The mean rTNSS of the long-term follow-up patients improved from 7.74 (95% confidence interval [CI] 7.507-7.974) at baseline to 2.604 (95% CI 2.221-2.986), P < .001, at 6 months and showed sustained improvement to 3.156 (95% CI 2.806-3.506), P < .001, at 3 years. The mean rTNNSS ranged from 1.301 (95% CI 1.112-1.491) at baseline to 0.564 (95% CI 0.441-0.688) ( P < .001) at 6 months and showed sustained improvement to 0.641 (95% CI 0.533-0.749) ( P < .001) at 3 years. The rTNSS subscores (sneezing, congestion, rhinorrhea, and itching) and rTNNSS subscores (lacrimation, eye itching, postnasal drip, and cough) remained significantly improved from the baseline at all follow-up time points (all P < .001). Conclusion Posterior nasal neurectomy significantly and sustainably alleviated nasal and non-nasal symptoms of perennial moderate and severe AR and improved patient quality of life through 3 years postprocedure.
Suture Tying Force for Cut-Out during Radial Meniscus Tear Repair: A Biomechanical Evaluation of Failure Loads during the Knot-Tying Process
Authors: Massey Patrick A. , Dudoussat Edwin , Montgomery Carver , Scalisi Wayne , McBride Hayden , Rutz Robert , Solitro Giovanni F. 
Published: September 2024

ObjectiveThe purpose of the study was to determine average tensile forces resulting in suture failure while tying a knot during repair of complete radial meniscus tears and to compare the failure tensile force based on meniscus tissue location: the peripheral (red-red) versus inner (white-white).DesignThis study was designed as a cadaveric biomechanical study using 24 menisci harvested from fresh frozen cadaveric knees with midbody radial tears. Tears were repaired using 2-0 nonabsorbable suture in both the inner meniscus and the peripheral meniscus. A force gauge was used to measure the tension of a surgeon’s knot until failure of either the suture or the meniscus tissue. Statistical analysis was performed comparing suture failure tensile forces between inner and peripheral sutures using 2-sample t test.ResultsSuture repairs primarily failed due to meniscal tissue cut-out after suture tensioning (96%). There was no statistical difference in failure mode between medial and lateral meniscus for both the inner (100% cut-out) and the peripheral (92% cut-out; P = 0.703) sutures. The peripheral sutures failed as significantly higher loads (54 ± 26 N) than the inner sutures (36 ± 11 N, P = 0.006). The peripheral meniscus tissue tolerated significantly higher tension at failure (36 ± 7 N) than the inner meniscus (26 ± 7 N, P < 0.001).ConclusionWhen tying parallel sutures to repair a radial meniscus tear, suture tensile forces above 30 N may tear through meniscus tissue. Surgeons should not use suture tying forces above 30 N when repairing radial meniscus tears with parallel sutures. The peripheral meniscus can withstand higher knot-tying forces than the inner meniscus, so surgeons should consider tying the peripheral suture before the inner suture.
Quality of Internet-Based Information on COVID-19 and Dentistry
Authors: Ayar Muhammet Kerim 
Published: September 2024

Aim: Dentists and their patients were at high risk for COVID-19 infection. As websites serve as a primary information source for many, this cross-sectional study aimed to assess the validity and reliability of information provided by websites regarding COVID-19 and dentistry. Materials and Methods: An online search was conducted on Google.com using the keywords ‘SARS CoV-2 and dentistry’, ‘COVID-19 and dentistry’ and ‘Coronavirus and dentistry’. The first 50 websites for each keyword were screened in incognito mode. After excluding duplicates, inaccessible and irrelevant websites, 88 websites remained for analysis. These websites were evaluated using the Health on the Net Foundation Code of Conduct (HON code) and the Journal of the American Medical Association (JAMA) benchmarks, which assess authorship, attribution, disclosure and currency of information. Descriptive statistical analyses, chi-square tests and one-way ANOVA were performed. Results: A total of 88 websites were found suitable for quality assessment. Only three of the websites had HON code accreditation. The mean JAMA benchmark score was 3.75 ± 0.7. The majority of the websites (62.5%) were academic, with a JAMA score of 3.84 ± 0.5. News and non-profit sites had the highest JAMA scores (4.0). Significant differences in JAMA scores were observed across different types of websites ( p < .05). Conclusions: The study found that the quality of websites providing information about COVID-19 and dentistry was generally high, especially among academic sites. This highlights the importance of high-quality online information to ensure that dentists and patients have access to accurate and reliable data during the pandemic.
Investigation of Cyclooxygenase-2 Expression in Tissue: Protein and mRNA Levels Compared Between Patients with Oral Squamous Cell Carcinoma and Oral Lichen Planus
Authors: Yazdandoust Yasaman , Arab Fatemeh , Kamyab Kambiz , Mohtasham Nooshin , Farshbaf Alieh , Sadeghi Ensieh Sagheb , Mohajertehran Farnaz 
Published: September 2024

Aim: Cyclooxygenase-2 (COX-2) is a crucial enzyme in the prostaglandin cascade. Overexpression of the COX-2 enzyme has been associated with the pathogenesis and progression of certain cancers, including oral cancer. This study aimed to investigate the quantitative expression and immunohistochemistry (IHC) expression of COX-2 in tissue samples from patients with oral squamous cell carcinoma (OSCC) and oral lichen planus (OLP) to gain insight into its potential role in the pathogenesis of these oral diseases. Methods: A total of 76 samples were analyzed, consisting of 25 cases of OSCC, 27 cases of OLP, and 24 cases of normal oral mucosa. COX-2 expression was analyzed using IHC staining and quantitative polymerase chain reaction (qPCR). Statistical analysis was performed using the Chi-squared, Spearman’s, and Fisher’s exact tests, with significance declared at a P value of <.05. Results: The mRNA expression of COX-2 in OSCC tissues (3.17 ± 1.02) was found to be significantly higher than in OLP (1.65 ± 0.72) and normal (1.08 ± 0.79; P < .01). In addition, protein expression of COX-2 was significantly higher in cancer tissues than in normal and OLP ( P < .05). The oral cavity was the most common tumor site in the studied cases, representing 56% of OSCC cases, as determined by qPCR analysis ( P < .05). Conclusion: Understanding the involvement of COX-2 in these oral diseases has implications for the development of targeted therapies and personalized treatment approaches. Also, the identification of COX-2 as a potential biomarker may contribute to improved diagnostic accuracy and prognosis in patients with OSCC and OLP. Moreover, the qPCR method could be as effective a technique as IHC to evaluate COX-2 amplification.
Prehospital computed tomography in a rural district for rapid diagnosis and treatment of stroke
Authors: Ibsen Jørgen , Hov Maren Ranhoff , Tokerud Gunn Eli , Fuglum Julia , Linnerud Krogstad Marianne , Stugaard Marie , Ihle-Hansen Hege , Lund Christian Georg , Hall Christian 
Published: September 2024

Background: Early diagnosis and triage of patients with ischemic stroke is essential for rapid reperfusion therapy. The prehospital delay may be substantial and patients from rural districts often arrive at their local hospital too late for disability-preventing thrombolytic therapy due to prolonged transport times. Methods: Hallingdal District Medical Centre (HDMC) is located in a rural area of Norway and is equipped with a computed tomography (CT) scanner. We established emergency pathways of CT imaging and thrombolytic treatment of patients with acute ischemic stroke at HDMC. During office hours these pathways were managed by a radiographer and a general physician supported by videoconference from the Primary Stroke Centre. Outside office hours we remotely controlled the CT exam and supported telestroke guided paramedics handling and examining the patients. With a primary aim of demonstrating the feasibility of this de novo concept we enrolled patients in the period 2017–2021 into a comparative cohort observational study. We compared patients treated at HDMC (the Rural CT group) to patients from two other rural regions in Norway with similar distances to their local hospital but without access to a rural CT scanner (the Reference group). Results: A total of 86 patients were included in the Rural CT group (mean age 74, 52% male, 43% stroke mimics), and 69 patients were included in the Reference group (mean age 70, 42% male, 28% stroke mimics). Median time from onset of symptoms to completed CT examination was 93 min in the Rural CT group as compared to 240 min in the Reference group ( p < 0.05). In patients receiving intravenous thrombolysis time from onset of symptoms to treatment was median 124 min in the Rural CT group and 213 min in the Reference group, p < 0.05. The frequency of thrombolysis for ischemic stroke did not significantly differ between the two groups. Conclusion: Combining prehospital rural CT examination with telestroke guided diagnosis and thrombolytic treatment by paramedics may facilitate earlier initiation of thrombolysis for patients with ischemic stroke.
Suitability of Minced Cartilage From Osteochondral Lesions of the Talus for Immediate Autograft Reimplantation
Authors: Williamson Emilie R. C. , Zhang Zijun , Motsay Morgan , Manchester Maggie , Campbell John T. , Cerrato Rebecca A. , Maloney Patrick J. , Schon Lew C. , Jeng Clifford L. 
Published: September 2024

Background: Particulated autograft cartilage implantation is a surgical technique that has been previously described for the repair of osteochondral lesions of the talus (OLT). It uses cartilage fragments harvested from the OLT that are minced into 1-2-mm3 fragments and then immediately reimplanted back into the chondral defect and sealed with fibrin glue during a single-stage surgery. The purpose of this study was to characterize the suitability of these minced cartilage fragments as immediate autograft for the treatment of OLTs. Methods: Thirty-one patients undergoing primary arthroscopic surgery for their OLT consented to have their loose or damaged cartilage fragments removed and analyzed in the laboratory. Harvested specimens were minced into 1- to 2-mm3 fragments and cell count, cell density, and cell viability were determined. In addition, physical characteristics of the OLT lesion were recorded intraoperatively and analyzed including size, location, Outerbridge chondromalacia grade of the surrounding cartilage, density of underlying bone, and whether the surgeon thought the OLT was primarily hyaline or fibrocartilage. Results: An average of 419 000 cells was able to be obtained from the harvested OLT fragments. The cells were 71.2% viable after mincing. Specimens from younger patients and from lesions with worse chondromalacia adjacent to the OLT had significantly higher cell numbers. Those from lateral lesions and with worse neighboring chondromalacia had a significantly higher cell density. None of the remaining physical OLT characteristics studied seemed to significantly affect cell number or viability. Conclusion: A large number of viable cells are available for immediate autografting by removing the loose or damaged cartilage from an OLT and mincing it into 1- to 2-mm3 fragments. These can be reimplanted into the chondral defect in a single-stage surgery. Future clinical studies are needed to determine if the addition of these live autologous cells either alone or in conjunction with other techniques significantly improves the quality of the repair tissue and clinical outcomes. Level of Evidence: Level IV, case series.
Evaluating the Femoral Atherosclerotic Plaque in Psoriasis Patients and Controls: A Case-Control Study
Authors: Ngo Vinh Minh , Ngo Hoang Xuan , Nguyen Hao Trong 
Published: September 2024

Background Psoriasis is a chronic inflammatory disease that can affect the skin or the cardiovascular system. The presence of femoral atherosclerotic plaque could be a promising sign in predicting cardiovascular risk for these patients. Objective The study aims to evaluate the prevalence of femoral atherosclerotic plaque between psoriasis and control individuals. Methods This case-control study involved 40 patients diagnosed with vulgaris psoriasis and 40 non-psoriasis individuals matched by age group and gender. We used clinical signs and symptoms to diagnose psoriasis and evaluated the disease’s severity using the Psoriasis Area and Severity Index (PASI). The atherosclerotic plaque on the femoral artery was detected using Doppler ultrasound to measure the femoral artery intima-media thickness (fIMT). Data were analyzed by SPSS 25. Results Male patients accounted for the proportion of 72.5%. In the psoriatic group, the mean value of PASI was 12.91 ± 6.73 (points). The proportion of femoral atherosclerotic plaque was significantly higher in the psoriasis compared to the controls (32.5% vs 10%; P = 0.014). Some factors associated with the femoral atherosclerotic plaque include age, smoking, and hypertension ( P < 0.05). Hypertension was an independent risk factor for femoral atherosclerotic after regression analysis. Conclusion Femoral atherosclerotic plaque is higher in psoriasis patients. This result emphasizes the need to screen for cardiovascular comorbidities in these patients.