bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of strontium aluminate‐printed nonwoven fabric from recycled cotton cellulose for smart wearable photochromic applications
Authors: Al‐Qahtani Salhah D. , Attia Yasser A. , Al‐Senani Ghadah M. 
Published: September 2024

AbstractSmart photochromic and fluorescent textile refers to garments that alter their colorimetric properties in response to external light stimulus. Cotton fibers have been reported as a main resource for many textile and non‐textile industries, such as automobiles, medical devices, and furniture applications. Cotton is a natural fiber that is distinguished with breathability, softness, cheapness, and highly absorbent. However, there have been growing demands to find other resources for cotton textiles at high quality and low cost for various applications, such as sensor for harmful ultraviolet radiation. Herein, we present a novel method toward luminescent and photochromic nonwoven textiles from recycled cotton waste. Using the screen‐printing technology, a cotton fabric that is both photochromic and fluorescent was developed using aqueous inorganic phosphor nanoparticles (10–18 nm)‐containing printing paste. Both CIE Lab color coordinates and photoluminescence spectra showed that the transparent film printed on the nonwoven fabric develops a reversible green emission (519 nm) under ultraviolet light (365 nm), even at low pigment concentration (2%) in the printing paste. Colorfastness of printed fabrics showed high durability and photostability.
A quantitative survey of correctional mental health professionals on current healthcare and treatment practices for transgender incarcerated persons
Authors: Bakman Paige , Berry Frank , Graham‐Howard Marjorie 
Published: September 2024

AbstractThere is a need for updated survey literature collected from correctional mental health professionals working within prison settings. Up to date research can add to the literature addressing the best practices for mental health treatment of the transgender incarcerated population in order to provide health care professionals and correctional staff with more effective, efficient, and widely understood intervention practices to facilitate the well‐being and safety of this population. Guided by three research aims, 50 mental health professionals from 21 states throughout the United States were surveyed in this quantitative survey regarding their work with the transgender incarcerated population. Results are discussed in terms of implications for the type of care and coordination of care provided by correctional mental health professionals.
Prevalence and associated factors of sexting among Taiwanese adolescents
Authors: Wei Hsi‐Sheng , Hsieh Yi‐Ping , Chen Yi‐Fu , Ma Josef Kuo‐Hsun , Lin Yu‐Sheng 
Published: September 2024

AbstractThis study utilized a large‐scale representative sample to explore the prevalence of sexting and its associated factors among adolescents in Taiwan. A total of 12,954 students in grade 5–12 countrywide were randomly selected to answer the sexting module of an online survey. 13.7% of the respondents reported having ever received sexts on cellphone, and 2.0% had sent sexts to others. The prevalence was higher among older adolescents. Gender differences were also found, in which female students were more likely to receive sexts (15.8% vs. 11.7%), while male students were at higher risk of sending sexts to others (2.9% vs. 1.1%). A series of hierarchical logistic regression were further performed to examine the associations between potential factors and receiving/sending sexts as the outcome variables. Age, gender, and time spending on texting were significantly associated with receiving and ending sexts. Online respect was found positively associated with receiving sexts but negatively associated with sending them. Privacy awareness was found not significantly associated with sexting. As the first national survey on this growing issue in Taiwan, the results of the present study highlighted the existence of sexting among local youth. Practice and policy implications were discussed.
New clinical insights into the treatment of benign uretero‐ileal anastomotic stricture following radical cystectomy and urinary diversion
Authors: Mou Yixuan , Yao Cenchao , Liu Zhenghong , Zhang Pu , Qi Xiaolong , Zhang Dahong , Chen Yiyang , Yu Weiwen , Wang Shuai 
Published: September 2024

AbstractBackgroundBenign uretero‐ileal anastomotic stricture (UIAS) is a potentially serious complication that can arise after radical cystectomy (RC) and subsequent urinary diversion. To preserve residual renal function and improve prognosis, it is crucial to derive insights from experience and tailor individualized treatment strategies for different patients.Patients and MethodsFrom October 2014 to June 2021, a total of 47 patients with benign UIAS underwent endoscopic management (n = 19) or reimplantation surgery (n = 28). The basic data, perioperative conditions, and postoperative outcomes of the two groups were compared and analyzed to evaluate efficacy.ResultsComparing preoperative and postoperative clinical efficacy within the same group, the endoscopic group showed no significant differences in creatinine and blood urea nitrogen (BUN) levels before surgery or after extubation (p > 0.05). However, significant differences were observed in glomerular filtration rate (GFR) levels on the affected side before surgery and after extubation (p < 0.05). In contrast, the laparoscopic reimplantation group did not exhibit significant differences in creatinine, BUN, or GFR levels of affected side before surgery and after extubation (p > 0.05). Postoperative clinical efficacy showed no significant difference in creatinine and BUN levels between the two groups (p > 0.05). However, GFR values of affected side in the endoscopic treatment group decreased more than those in the laparoscopic reimplantation group (p < 0.05). Additionally, the laparoscopic reimplantation group was able to remove the single‐J tube earlier than the endoscopic treatment group (p < 0.05), had a lower recurrence rate of hydronephrosis after extubation (p < 0.05), and experienced a later onset of hydronephrosis compared to the endoscopic treatment group (p < 0.05).ConclusionsBased on our experience in treating UIAS following RC combined with urinary diversion, laparoscopic reimplantation effectively addresses the issue of UIAS, allowing for the removal of the ureteral stent relatively soon after surgery. This approach maintains long‐term ureteral patency, preserves residual renal function, reduces the risk of ureteral restenosis and hydronephrosis, and has demonstrated superior therapeutic outcomes in this study.
Essential Oil Extracted from Lippia sidoides Cham. (Verbenaceae) Induces Cell Cycle Arrest, Apoptosis, and Antimigratory Effects in Melanoma Cells
Authors: Volpe‐Fix Andressa Roehrig , da Silva Sales Felipe , Caperuto Luciana Chagas , Lago João Henrique Ghilardi , Machado‐Jr Joel 
Published: September 2024

AbstractMelanoma, the most aggressive form of skin cancer, poses a substantial global health threat with increasing incidence rates. Although novel targeted therapies have improved melanoma treatment, challenges persist due to poor response rates and drug resistance. Plant‐derived compounds have been crucial in anticancer drug discovery, with many natural products demonstrating the ability to target molecular pathways involved in tumor development. In this study, the anti‐melanoma potential of essential oil extracted from the aerial parts of Lippia sidoides Cham. (EO‐LS), composed mainly by the monoterpene thymol (96 %), was demonstrated. Obtained results demonstrated that EO‐LS disrupted critical cancer hallmarks in A2058 melanoma cells harboring the BRAFV600E mutation. Specifically, EO‐LS induced G1‐phase cell cycle arrest and apoptosis, as assessed by annexin‐V, caspase‐3 activity, and TUNEL assays. EO‐LS also inhibited cell migration and disrupted the AKT signaling pathway, which is a critical regulator of melanoma progression. Furthermore, a dose‐dependent increase in reactive oxygen species (ROS) generation was observed, indicating pro‐oxidant properties. These findings highlighted the significant in vitro anticancer properties of EO‐LS suggesting its potential as a promising molecular scaffold for developing of novel anti‐melanoma candidates.
A Novel Dipterocarpol Derivative That Targets Alpha‐Glucosidase and NLRP3 Inflammasome Activity for Treatment of Diabetes Mellitus
Authors: Danilov Roman D. , Smirnova Irina E. , Galimova Zarema I. , Sokolova Elena V. , Lukyanov Andrey V. , Kalitin Konstantin Y. , Mukha Olga Y. , Babkov Denis A. , Kazakova Oxana B. , Spasov Alexander A. 
Published: September 2024

AbstractType 2 diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia, chronic inflammation, impaired insulin secretion, and/or peripheral insulin resistance. Current α‐glucosidase inhibitors approved for clinical use exhibit limited efficacy compared to other glucose‐lowering agents. In this study, a series of mono‐ and bis‐benzylidene derivatives were synthesized via aldol condensation of 3‐oxo‐dammarane triterpenoids with terephthalic aldehyde. The target mono‐ and bis‐benzylidene derivatives, based on the dammarane triterpenoids hollongdione 1, (20S)‐23,24‐epoxy‐25,26,27‐trinordammar‐3,24‐dione 2, and 24(R,S)‐20(S)‐epoxy‐25‐hydroxy‐dammar‐3‐one 3, were successfully synthesized. Several of these inhibitors demonstrated significantly greater efficacy than the reference drug acarbose. Notably, compound 4 inhibited S. cerevisiae α‐glucosidase with an IC50 of 2.67 μM. Furthermore, the target compounds effectively inhibited NLRP3 inflammasome activation, reducing IL‐1β production in LPS+ATP‐stimulated murine peritoneal macrophages without detectable cytotoxicity. Compound 8, which exhibited dual activity, was further characterized as an inhibitor of NLRP3 activation in peripheral blood mononuclear cells, leading to the prevention of pyroptosis and IL‐1β release. Additionally, compound 8 was shown to promote neuronal survival in LPS+ATP‐treated rat hippocampal slices, highlighting its potential as a promising antidiabetic agent that targets both postprandial hyperglycemia and metaflammation.
Heterocyclic Compounds as CDK9 Inhibitors: Structural Diversity, Mechanism of Action, and Therapeutic Potential in Cancer and Beyond
Authors: Bose Kuntal , Shajahan Afiya , Sreekumar Nandana , Aneesh T. P. 
Published: September 2024

AbstractCyclin‐dependent kinases (CDKs) are crucial proteins involved in key cellular processes, such as cell division and transcription. Their dysregulation plays a significant role in cancer development. Inhibiting cyclin‐dependent kinase 9 (CDK9) impacts several survival pathways in cancer cells, presenting a promising therapeutic approach for various cancers. CDK9, in association with cyclin T1, forms the positive transcription elongation factor b (P‐TEFb) complex, which phosphorylates the C‐terminal domain (CTD) of RNA polymerase II (Pol II). This phosphorylation promotes the transition from transcription initiation to elongation. This review examines recent advancements in CDK9 modulators, with a particular emphasis on compounds currently in clinical trials.
Aldehyde‐based Activation of C2α‐lactylthiamin Diphosphate Decarboxylation on Bacterial 1‐deoxy‐d‐xylulose 5‐phosphate Synthase
Authors: Toci Eucolona M. , Majumdar Ananya , Meyers Caren L. Freel 
Published: September 2024

Abstract1‐Deoxy‐d‐xylulose 5‐phosphate synthase (DXPS) catalyzes the thiamin diphosphate (ThDP)‐dependent formation of DXP from pyruvate (donor substrate) and d‐glyceraldehyde 3‐phosphate (d‐GAP, acceptor substrate) in bacterial central metabolism. DXPS uses a ligand‐gated mechanism in which binding of a small molecule “trigger” activates the first enzyme‐bound intermediate, C2α‐lactylThDP (LThDP), to form the reactive carbanion via LThDP decarboxylation. d‐GAP is the natural acceptor substrate for DXPS and also serves a role as a trigger to induce LThDP decarboxylation in the gated step. Additionally, we have shown that O2 and d‐glyceraldehyde (d‐GA) can induce LThDP decarboxylation. We hypothesize this ligand‐gated mechanism poises DXPS to sense and respond to cellular cues in metabolic remodeling during bacterial adaptation. Here we sought to characterize features of small molecule inducers of LThDP decarboxylation. Using a combination of CD, NMR and biochemical methods, we demonstrate that the α‐hydroxy aldehyde moiety of d‐GAP is sufficient to induce LThDP decarboxylation en route to DXP formation. A variety of aliphatic aldehydes also induce LThDP decarboxylation. The study highlights the capacity of DXPS to respond to different molecular cues, lending support to potential multifunctionality of DXPS and its metabolic regulation by this mechanism.
Toward Artificial Photosynthetic Assemblies Inspired by Photosynthetic Bacteria
Authors: Han Yifei , Li Zhan‐Ting , Tian Jia 
Published: September 2024

AbstractThe photosynthetic assemblies in bacteria, as critical structures in early evolutionary photosynthesis, are pivotal for understanding the molecular mechanisms of photosynthesis and for the design of artificial photosynthetic systems. In recent decades, various artificial systems based on synthetic molecules have been developed to mimic these photosynthetic assemblies from structures to functions. This review summarizes the latest advancements in mimicking the photosynthetic assembly systems, discussing three fundamental models: the chlorosome and related complexes in green bacteria, the chromatophore and reaction center system in purple bacteria, and the phycobilisome and photosystem II (PSII) in cyanobacteria, along with their representative mimicking systems. We also address the challenges and unexplored areas in the simulation of photosynthetic systems.
Two‐Fold Oxidative Coupling of Furan with Indole Provides Modular Access to a New Class of Tetra‐(Hetero)Arylated Furans with Up to Four Different Substituents
Authors: Mhaske Krishna , Gangai Shon , Taneja Neha , Narayan Rishikesh 
Published: September 2024

AbstractHighly arylated propeller‐shaped heteroarenes constitute an intriguing class of molecular scaffolds for material science applications. Among these, tetraarylated furans demonstrate differentiated properties as compared to other similar heterocyclic cores. The synthetic complexity to access tetraarylated furans increases significantly with increasing number of different peripheral aryl groups. There are only a very limited number of methodologies available to access furans with four different (hetero)aryl substituents. Notably, none of these involve direct oxidative coupling on the furan core as the method of choice. Herein, we report the first methodology based on a sequential two‐fold oxidative C−C coupling of furans with indoles to access bis(indolyl)furans (BIFs) ‐ a new class of ‘extremely congested’ tetra‐(hetero)arylated furans with up to four different substituents. The reaction is mediated by inexpensive, earth‐abundant FeCl3⋅6H2O and displays high efficiency, wide substrate scope, modularity and aqueous compatibility. Moreover, we also present the first validation of the distinct aggregation‐caused quenching (ACQ) property of the tetraarylated furans beyond only phenyls as peripheral groups and disclose new mechanistic underpinnings for the same.
High Efficiency and Total Decomposition of Water by Pt−CoFe@CC Catalyst Loaded with a Small Amount of Pt
Authors: Bi Yanqin , Zhao Zenghua , Qian Jianhua , Chen Liangliang , Duan Chunyang 
Published: September 2024

AbstractThe development of bifunctional electrocatalysts coupled with HER and OER activities in the same electrolyte to achieve overall water decomposition is more attractive and challenging for practical applications. Here, we prepared a CoFe‐LDH catalyst via a hydrothermal method, and grew highly dispersed Pt−CoFe@CC bifunctional catalyst on a carbon cloth via the ethylene glycol thermal reduction method. The low content of Pt was limited to CoFe‐LDH to balance the catalytic performance and cost, to achieve effective water decomposition. Surprisingly, the overall decomposition of water can be achieved with a voltage of only 1.6 V and good stability for up to 20 hours. This work provides a design idea and method for combining HER and OER bifunctional electrocatalysts.
A Novel Approach to the Structural Design of Dual‐State Emission Luminogens by Combining Tetraphenylethylene with Anthracene via Dihydroisoxazole
Authors: Lu Wenjun , Zhao Yingyi , Sun Baiwang 
Published: September 2024

AbstractDual‐state emission luminescent materials (DSEgens), which exhibit bright emissions in boththe solid state and solution, have been attracting research interest in the design of multifunctional materials.The delicate manipulation of molecular structures remains challenging in the synthesis of DSEgens. In this article, two novel molecules with dual‐state emission were synthesized by combining tetraphenylethylene with anthracene via dihydroisoxazole. Tetraphenylethylene acts as a solid‐state emitter, while the anthracene core functions as an emitter in the solution state to achieve DSE fluorescence properties. The THF/DCM mixture resulted in successfully obtaining the crystal structures of TPE−An−H and TPE−An−Cl. The quantum yields (QYs) of TPE−An−H were 31 % and 42 % in EA and the solid state, respectively, while TPE−An−Cl exhibited QYs of 32 % and 34 %. The novel synthesis method in this paper combines AIE with ACQ via dihydroisoxazole to achieve dual‐state emission, offering a new and concise approach.
Regulation of Ir Dopant in Mo Oxides by Flame Spray Pyrolysis for Efficient CO2 Hydrogenation
Authors: Sun Xingtao , Yu Jiafeng , Zada Habib , Ge Qingjie , Sun Jian 
Published: September 2024

AbstractMo carbide is recognized as one of the most promising catalysts for CO2 utilization via reverse water‐gas shift (RWGS). However, the catalysts always suffered from low processing capacity, undesired products and deactivation. Herein, an Ir modified MoO3 synthesized by the flame spray pyrolysis (FSP) method exhibits higher reaction rate (63.0 gCO2 gcat−1 h−1) compared to the one made by traditional impregnation method (45.8 gCO2 gcat−1 h−1) over the RWGS reaction at 600 °C. The distinguishing feature between the two catalysts lies in the chemical state and space distribution of Ir species. Ir species predominated in the bulk phase of MoO3 during the quenching process of the FSP method and were mainly in the metallic states, which was revealed by X‐ray absorption spectroscopy (XAS), X‐ray photoelectron spectroscopy (XPS), and time‐of‐flight secondary ion mass spectroscopy (ToF‐SIMS) characterizations. In contrast, the Ir introduced via the impregnation method was mainly on the surface of MoO3 and in the oxidized state. The regulation of Ir dopant in MoO3 catalyst by different methods determines the carbonization process from MoO3 to Mo carbides and thus affects the catalytic performance over RWGS reaction. This work sheds light on the superiority of the FSP method in synthesizing Mo oxides with heteroatoms and further creating an efficient Mo‐based catalyst for CO2 conversion.
Evidence of Differential Prediction of Anxiety and Depression by Diurnal Alpha‐Amylase and Cortisol in Development
Authors: McCurdy Bethany H. , Weems Carl F. , Bradley Travis , Matlow Ryan , Carrión Victor G. 
Published: September 2024

ABSTRACTResearch and theory suggest an important role of neuroendocrine function in emotional development, particularly under conditions of elevated stress. We provide empirical data to clarify associations between alpha‐amylase (AA) and cortisol as well as test the differential linkages among AA, cortisol, and symptoms of anxiety, depression, and posttraumatic stress in children. Children recruited from a low‐income elevated violence community (n = 100; mean age = 10, SD = 0.64; 79% Latino; 67% received free or reduced lunch) were assessed on diurnal levels of AA and cortisol along with assessments of anxiety, depression, and posttraumatic stress symptoms (PTSS). Elevated anxiety symptoms were associated with steeper linear slopes of AA with higher levels of AA in the morning but lower levels of AA in the evening. Depression was associated with differential cubic trajectories of AA when PTSSs were included in the model. Anxiety also predicted differential cubic diurnal trends in cortisol, such that greater anxiety symptoms were associated with relatively higher levels of cortisol in the evening. Again, depression symptoms when PTSS were included predicted diurnal cubic trends with elevated depression associated with lower awakening and midday cortisol that reversed to higher evening cortisol compared to youth with fewer self‐reported depression symptoms.
Neurodiversity in the workplace: An agenda for research and action
Authors: Hartman Lorne M. , Hartman Braxton L. 
Published: September 2024

AbstractThis paper considers human resource practices in the workplace that represent barriers to hiring, onboarding, and managing autistic employees. In particular, we focus on the development of bias‐free selection processes to minimize discrimination against autistic job candidates, determining whether and how accommodations affect productivity of autistic employees, and changing attitudes toward autistic employees in the workplace. Implications for future research and recommendations for autism awareness training are provided. Finally, the alignment of organizational systems that facilitate successful employment experiences for autistic adults is explored.
Why do understorey Licuala palm fruits turn from red to white and then black when ripe?
Authors: Er Kenneth B. H. , Nguyen Derrick H. D. , Yeoh Yi Shuen , Khoo Max D. Y. , Choo Ruisheng , Tay Li Si , Soh Sun Yi , Jamil Zaki , Ang Wee Foong , Loo Adrian H. B. 
Published: September 2024

AbstractLicuala ferruginea Becc., a tropical forest understorey palm, is observed to have fruits that appear red in colour when unripe, turning pink, then white, purple and finally black in colour as they ripen. We monitored 13 fruiting palms in rainforest fragments and recorded the consumption of fruits by animals via camera traps. We also documented the fruiting phenology of two palms in the nursery. In the rainforest fragments, a Cream‐vented Bulbul (Pycnonotus simplex) was observed plucking a mature purple fruit from a L. ferruginea palm, before flying away with the fruit in its beak. This was the only bird that was observed feeding on the mature fruit. A range of mammals, dominated by edge species such as the Long‐tailed Macaque and Wild Boar, were observed to consume L. ferruginea fruits indiscriminately across all five colour stages, thereby limiting the dispersal of the fruits. Forest bulbul gape sizes also matched the fruit size, suggesting that forest bulbuls are the likely dispersers of the palm in the original forest where edge species are not in high densities. We further posit that the initial phase of red fruits, with high contrasting red reflectance against a green foliage background, might be a form of early advertisement to birds. The fruit then turns pink and white, which have high green reflectance and is less contrasting, thereby reducing the conspicuity of the fruit. This allows the fruit to ripen with high fructose and glucose content, and turn purple and black, which are known visual cues for birds. This study provides indicative support for the dispersal syndrome hypothesis and highlights the potential effects of forest fragmentation on plant–frugivore interactions.