bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experience in creating primary cultures of endometrial cancer and studying cells carrying phenotype of cancer stem cells
Authors: Filippova S. Yu. , Mezhevova I. V. , Chembarova T. V. , Novikova I. A. , Verenikina E. V. , Zhenilo O. E. , Polovodova V. V. , Shaposhnikov A. V. , Shalashnaya E. V. , Maslov A. A. , Ishonina O. G. 
Published: September 2024

Purpose of the study. Was to investigate the possibility of applying the method of spheroid formation in culture for assessment of the endometrial cancer (EC) tumor stem cells (TSC) content in complex samples containing various tumor cells and microenvironment.Materials and methods. Primary cultures were obtained from fragments of tumors removed during surgery as a first stage of treatment at the Department of Gynecological Oncology, the National Medical Research Center for Oncology. After enzymatic disaggregation of tissue, cell suspension was passaged in DMEM medium containing 10 % fetal bovine serum and 1 % gentamicin to obtain primary two-dimensional cultures. To study the ability of cells to form spheroids, the primary culture was removed from the culture plate and passaged with 2.0 × 104 cells per well of a six-well plate (n = 6) in DMEM medium containing 0.35 % agarose and growth factors EGF (20 ng/ml) and FGF (20 ng/ml). After two weeks of cultivation, the average size, number of formed spheroids, and frequency of spheroid formation were determined. For those cultures that had formed spheroids, immunofluorescent staining of the two-dimensional culture for the marker CD133 was performed, after which the frequency of CD133+ cells was determined.Results. A total of nine primary cultures of EC were obtained, five of which formed spheroids within two weeks of cultivation under non-adhesive conditions. In these cultures, small polygonal CD133+ cells showed the strongest association with spheroid formation, which were associated with the largest spheroids (98–110 μm in diameter).Conclusion. There is a large number of microenvironmental cells in mixed cultures of CSC, some of which may express CD133, including healthy stem cells that also form spheroids in soft agar. A more detailed study of CSC subpopulations compared to normal endometrium is required to establish a link between the observed diversity of cells in culture and their ability to form spheroids and other characteristics of tumor stem cells.
Eight New Substellar Hyades Candidates from the UKIRT Hemisphere Survey
Authors: Schneider Adam C. , Cushing Michael C. , Stiller Robert A. , Munn Jeffrey A. , Vrba Frederick J. , Bruursema Justice , Williams Stephen J. , Liu Michael C. , Bravo Alexia , Faherty Jacqueline K. , Rothermich Austin , Calamari Emily , Caselden Dan , Kabatnik Martin , Sainio Arttu , Bickle Thomas P. , Pendrill William , Stevnbak Andersen Nikolaj , Thévenot Melina 
Published: September 2024

Abstract
We have used the UKIRT Hemisphere Survey combined with the UKIDSS Galactic Cluster Survey, the UKIDSS Galactic Plane Survey, and the CatWISE2020 catalog to search for new substellar members of the nearest open cluster to the Sun, the Hyades. Eight new substellar Hyades candidate members were identified and observed with the Gemini/GNIRS near-infrared spectrograph. All eight objects are confirmed as brown dwarfs with spectral types ranging from L6 to T5, with two objects showing signs of spectral binarity and/or variability. A kinematic analysis demonstrates that all eight new discoveries likely belong to the Hyades cluster, with future radial velocity and parallax measurements needed to confirm their membership. CWISE J042356.23+130414.3, with a spectral type of T5, would be the coldest (T
eff ≈ 1100 K) and lowest-mass (M ≈ 30 M
Jup) free-floating member of the Hyades yet discovered. We further find that high-probability substellar Hyades members from this work and previous studies have redder near-infrared colors than field-age brown dwarfs, potentially due to lower surface gravities and supersolar metallicities.
Nitrogen Abundance Distribution in the Inner Milky Way
Authors: Pineda Jorge L. , Horiuchi Shinji , Anderson L. D. , Luisi Matteo , Langer William D. , Goldsmith Paul F. , Kuiper Thomas B. H. , Fischer Christian , Gong Yan , Brunthaler Andreas , Rugel Michael , Menten Karl M. 
Published: September 2024

Abstract
We combine a new Galactic plane survey of hydrogen radio recombination lines (RRLs) with far-infrared surveys of ionized nitrogen, N+, to determine nitrogen abundance across Galactic radius. RRLs were observed with the NASA Deep Space Network Station 43 70 m antenna and the Green Bank Telescope in 108 lines of sight spanning −135°< l < 60°, at b = 0°. These positions were also observed in [N ii] 122 μm and 205 μm lines with the Herschel Space Observatory. Combining RRL and [N ii] 122 μm and 205 μm observations in 41 of 108 samples with high signal-to-noise ratio, we studied the ionized nitrogen abundance distribution across Galactocentric distances of 0–8 kpc. Combined with existing solar neighborhood and outer Galaxy N/H abundance determinations, we studied this quantity’s distribution within the Milky Way’s inner 17 kpc for the first time. We found a nitrogen abundance gradient extending from Galactocentric radii of 4–17 kpc in the Galactic plane, while within 0–4 kpc the N/H distribution remained flat. The gradient observed at large Galactocentric distances supports inside-out galaxy growth, with the additional steepening resulting from variable star formation efficiency and/or radial flows in the Galactic disk, while the inner 4 kpc flattening, coinciding with the Galactic bar’s onset, may be linked to radial flows induced by the bar potential. Using SOFIA/FIFI-LS and Herschel/PACS, we observed the [N iii] 57 μm line to trace doubly ionized gas contribution in a subsample of sight lines. We found negligible N++ contributions along these sight lines, suggesting mostly singly ionized nitrogen originating from low-ionization H ii region outskirts.
A Statistical Analysis of Crab Pulsar Giant Pulse Rates
Authors: Doskoch Graham M. , Basuroski Andrea , Halley Kriisa , Sookram Avinash , Rodriguez-Ramos Iliomar , Nahata Valmik , Rahman Zahi , Zhang Maureen , Uhlmann Ashish , Lynch Abby , Lewandowska Natalia , Miranda Nohely , Schmiedekamp Ann , Schmiedekamp Carl , McLaughlin Maura A. , Reichart Daniel E. , Haislip Joshua B. , Kouprianov Vladimir V. , White Steve , Ghigo Frank , Heatherly Sue Ann 
Published: September 2024

Abstract
A small number of pulsars are known to emit giant pulses (GPs), single pulses much brighter than average. Among these is PSR J0534+2200, also known as the Crab pulsar, a young pulsar with high GP rates. Long-term monitoring of the Crab pulsar presents an excellent opportunity to perform statistical studies of its GPs and the processes affecting them, potentially providing insight into the behavior of other neutron stars that emit bright single pulses. Here, we present an analysis of a set of 24,985 Crab GPs obtained from 88 hr of daily observations at a center frequency of 1.55 GHz by the 20 m telescope at the Green Bank Observatory, spread over 461 days. We study the effects of refractive scintillation at higher frequencies than previous studies and compare methods of correcting for this effect. We also search for deterministic patterns seen in other single-pulse sources, possible periodicities seen in several rotating radio transients and fast radio bursts, and clustering of GPs like that seen in the repeating fast radio burst FRB 121102.
Fermi and eROSITA Bubbles as Persistent Structures of the Milky Way
Authors: Shimoda Jiro , Asano Katsuaki 
Published: September 2024

Abstract
The Fermi and eROSITA bubbles (FBs and eRBs), large diffuse structures in our Galaxy, can be the by-products of steady star formation activity. To simultaneously explain the star formation history of the Milky Way (MW) and the metallicity of ∼Z
⊙ at the Galactic disk, a steady Galactic wind driven by cosmic rays (CRs) is required. For tenuous gases with a density of ≲10−3 cm−3, CR heating dominates over radiative cooling, and the gas can maintain the virial temperature of ∼0.3 keV, ideal for escape from the Galactic system as the wind. A part of the wind falls back onto the disk like a Galactic fountain flow. We model the wind dynamics according to the Galactic evolution scenario and find that the scale height and surface brightness of the X-ray and the hadronic gamma-ray emissions from such fountain flow region can be consistent with the observed properties of the FBs and eRBs. This implies that the bubbles are persistent structures of the MW existing over (at least) the last ∼1 Gyr rather than evanescent structures formed by nontrivial, ∼10 Myr past Galactic center transient activities.
Observations of Kappa Distributions in Solar Energetic Protons and Derived Thermodynamic Properties
Authors: Cuesta M. E. , Cummings A. T. , Livadiotis G. , McComas D. J. , Cohen C. M. S. , Khoo L. Y. , Sharma T. , Shen M. M. , Bandyopadhyay R. , Rankin J. S. , Szalay J. R. , Farooki H. A. , Xu Z. , Muro G. D. , Stevens M. L. , Bale S. D. 
Published: September 2024

Abstract
In this paper, we model the high-energy tail of observed solar energetic proton energy distributions with a kappa distribution function. We employ a technique for deriving the thermodynamic parameters of solar energetic proton populations measured by the Parker Solar Probe Integrated Science Investigation of the Sun EPI-Hi high-energy telescope, over energies from 10 to 60 MeV. With this technique, we explore, for the first time, the characteristic thermodynamic properties of the solar energetic protons associated with an interplanetary coronal mass ejection (ICME) and its driven shock. We find that: (1) the spectral index or, equivalently, the thermodynamic parameter kappa of solar energetic protons (κ
EP) gradually increases, starting from the pre-ICME region (upstream of the CME-driven shock), reaching a maximum in the CME ejecta (κ
EP ≈ 3.5), followed by a gradual decrease throughout the trailing portion of the CME; (2) the solar energetic proton temperature and density (T
EP and n
EP) appear anticorrelated, a behavior consistent with subisothermal polytropic processes; and (3) values of T
EP and κ
EP appear to be positively correlated, indicating an increasing entropy with time. Therefore, these proton populations are characterized by a complex and evolving thermodynamic behavior, consisting of multiple subisothermal polytropic processes, and a large-scale trend of increasing temperature, kappa, and entropy. This study and its companion study by Livadiotis et al. open up a new set of procedures for investigating the thermodynamic behavior of energetic particles and their shared thermal properties.
Outcomes of Minimally Invasive Locking Plate Osteosynthesis for Periprosthetic Distal Femur Fractures following Primary Total Knee Arthroplasty
Authors: Gannamani Subramaniam , Kavikondala Raghu , Joseph Vinay Mathew , Harsha Takkalapally , Rachakonda Kamalakar Rao , Reddy Annappareddy V. Gurava 
Published: September 2024

Abstract

Introduction:
Periprosthetic distal femur fractures have been on the rise with an increasing number of total knee arthroplasties being performed. In addition to regular fixation principles in distal femur fractures, periprosthetic fractures pose additional challenges due to osteoporotic bone and preexisting medical comorbidities.

Materials and Methods:
We retrospectively analyzed 31 patients who underwent surgical fixation with a locking plate using a minimally invasive technique for periprosthetic distal femur fractures at a single level 1 orthopedic hospital for 4 years.

Results:
Out of the 31 patients included in the study, 21 were female. The mean age of the study population was 65.63 years, ranging from 51 to 82 years. The mean time to union was 14.32 weeks, with a range from 12 to 22 weeks. The average Knee Society Score was 78.2, which is considered a good outcome. There was one case of implant failure in our case series, which could be attributed to immediate weight bearing.

Conclusion:
In conclusion, we found that fixation of supracondylar femur fractures associated with stable nonstemmed total knee arthroplasty with a locking plate using a minimally invasive technique yielded good results.
Arthroscopic Rotator Cuff Repair in the Elderly: Long-Term Outcomes
Authors: Sangani Karthik , Adla Deepthi Nandan Reddy 
Published: September 2024

Abstract

Introduction:
Rotator cuff tear (RCT) is one of the most common ailments around the shoulder. Its incidence increases significantly with age. However, owing to the variable healing potential and retear rates, the ideal management of RCT in the elderly is still up for debate. The purpose of this study is to observe and analyze the long-term functional outcomes in patients older than 60 years of age, who have undergone arthroscopic RCT repair.

Methods:
Fifty-seven cases who had undergone arthroscopic RCT repair with a minimum postoperative follow-up for 3 years were identified, in this single surgeon monocentric retrospective study. They were assessed using shoulder pain and disability index (SPADI) scoring.

Results:
Out of the 57 patients with ages more than 60 years, 10 were beyond 70 years of age. The mean age of the group was 65.2 years (standard deviation [SD] =4.86) ranging from 60 to 84 years. The mechanism of injury was atraumatic in 27 cases. The mean follow-up period was 57.9 months (SD = 15.7). The cases were categorized based on the number of rotator cuff tendons involved in the tear. The mean SPADI% for pain in all the cases was 0.98% (SD = 2.1). Forty-two out of the total 57 cases had a SPADI of 0%. They were completely asymptomatic, with their operated shoulder as good as the other. No statistically significant correlation was found between the SPADI scores and the number of tendons repaired (r = 0.06).

Conclusion:
An optimal tension-free arthroscopic repair of the RCT can yield good results even in the elderly. The age of the patient, the duration of the tear before surgery, and the size of the tear should not be considered as a stand-alone factor to deny surgical management if the fatty infiltration is within a limit. Irrespective of the retear rates the overall functional outcomes are still good.
SOCIAL AND ECONOMIC DEVELOPMENT OF THE NORTH OSSETIAN ASSR DURING THE 5TH AND 6THFIVE-YEAR PLANS
Authors: БАБАЕВ Т.З. 
Published: September 2024

В статье рассматривается влияние развития народного хозяйства Северной Осетии на уровень жизни граждан республики в 1950-е гг., в период прохождения регионом значительных преобразований. Основное внимание уделено промышленности и сельскому хозяйству, которые столкнулись с множественными вызовами в повышении материального благосостояния граждан. Несмотря на трудности, с помощью государственной поддержки и помощи со стороны промышленных предприятий аграрный сектор смог не только восстановиться после военных разрушений, но и значительно увеличить свою производственную мощность. В статье анализируются периоды пятой и шестой пятилеток, когда происходила активная реконструкция и строительство новых промышленных объектов, способствовавших расширению производственных мощностей и увеличению выпуска промышленной продукции. Отмечено, что промышленное производство стало ведущим сектором экономики республики; уделено внимание развитию новых отраслей, включая машиностроение. Параллельно шло значительное укрупнение колхозов и повышение эффективности сельскохозяйственного производства. В статье подчеркивается, что взаимодействие промышленных и аграрных секторов, подкрепленное государственными инвестициями и политикой, способствовало общему росту и улучшению уровня жизни населения в Северной Осетии.
The article examines the impact of the development of the national economy of North Ossetia on the standard of living of citizens of the republic in the 1950s, a period of significant transformations in the region. The main attention is paid to industry and agriculture, which faced multiple challenges in improving the material well-being of citizens. Despite the difficulties, with the help of state support and assistance from industrial enterprises, the agricultural sector was able not only to recover from the devastation of war, but also to significantly increase its production capacity. The article analyzes the periods of the fifth and sixth five-year plans, when there was an active reconstruction and construction of new industrial facilities, which contributed to the expansion of production capacity and an increase in industrial output. It is noted that industrial production became the leading sector of the republic's economy; attention is paid to the development of new industries, including mechanical engineering. In parallel, there was a significant consolidation of collective farms and an increase in the efficiency of agricultural production. The article emphasizes that the interaction of industrial and agricultural sectors, supported by government investment and policy, contributed to overall growth and improvement of the standard of living of the population in North Ossetia.
THE EFFECTS OF MONEY PRIMING ON RISK-TAKING BEHAVIOR
Authors: Okamura Yasuto 
Published: September 2024

Studies have found that exposure to money influences human behaviors. This study examines the effects of money priming on risk-taking. When either exposed or not exposed to money priming, participants responded to the likelihood that they would engage in unsafe behaviors and the perceived risk of these behaviors. The results revealed that individuals tended to exhibit more risky behavior when they were exposed to money priming. The theoretical implications of these findings and various directions for further research are discussed.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0710/a.php" alt="Hit counter" /></p>
STRATEGIC MARKETING ORIENTATIONS FOR SOCIAL VALUE GENERATION: SYSTEMATIC LITERATURE REVIEW AND RESEARCH AGENDA
Authors: Mazzarolo Aloisio Henrique , Mainardes Emerson Wagner , Sepulcri Lara Mendes Christ Bonella , Polastri de Olive Anna Beatriz Simonetti 
Published: September 2024

<p>This study aimed to identify research that addresses strategic marketing orientations from a social perspective and to discuss how studies in this area have been related over time. From the Web of Science database, we analyzed 104 studies and conducted a systematic literature review followed by bibliometric analysis. The bibliometric analysis showed the main focus of studies on strategic marketing orientation aimed at generating social value: service-dominant logic (SD-Logic), social entrepreneurship, customer participation in innovation, innovation capabilities, product development, and social marketing. The analysis and reading of the selected articles allowed us to conclude that investigations into strategic marketing orientations with a social bias are scarcely present in the literature, highlighting the need for further studies to develop knowledge on the subject.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0821/a.php" alt="Hit counter" /></p>
SELECTING EXERCISES TO IMPROVE LONG JUMP PERFORMANCE FOR K54 MALE STUDENTS OF NAM DINH UNIVERSITY OF TECHNOLOGY EDUCATION
Authors: Kien Nguyen Trung , Anh Nguyen Duc , Dong Tran Van , Kiên Lê Trung , Ngan Nguyen Thuy 
Published: September 2024

Using regular scientific research methods, 18 exercises were selected to improve long jump performance for K54 male students at Nam Dinh University of Technology Education. Initial application of selected exercises in practice has shown good effectiveness in improving long jump performance for K54 male students at the Nam Dinh University of Technology Education.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0701/a.php" alt="Hit counter" /></p>
PERCEIVED BARRIERS TO PHYSICAL ACTIVITY AMONG COLLEGE STUDENTS: BASIS FOR INTERVENTION PROGRAM
Authors: Dagum Junessa S. , Cabanog Lawrence T. , Auman Irene May M. , Galaura Lenziel L. 
Published: September 2024

The researchers were motivated to conduct this study to help the researchers know and become aware of all the problems and challenges of college students, as well as their perceived barriers and, through information gathered, students in the university. The purpose of this study was to determine the perceived barriers to physical activity and its relevance to college students— the 379 college students from different departments at a private institution in the University of Mindanao. To analyze the data, the researcher used the descriptive- survey research design, a modified questionnaire from a prior study, and mean and Pearson’s r to analyze the data. The findings revealed that the participants’ exposure and differences in perceived barriers to physical activity by gender, age, and year level are high. The level of exposure and gender, age, and year level of the respondents are significantly related. In addition, this refers to a person’s behavior as an obstacle to carrying out a prescribed health action. A person’s perception of barriers or limitations differs enormously, leading to a cost or benefit analysis.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0770/a.php" alt="Hit counter" /></p>
ICT LITERACY AND ADOPTION OF P.E. TEACHERS: BASIS FOR INTERVENTION
Authors: Singson Ivy V. , Abajar Junry H. 
Published: September 2024

Despite all of the advantages of incorporating information and communication technology (ICT) into education, applying ICT to the subject of physical education (P.E.) remains a significant challenge for teachers due to the specific nature of the class: the motor aspect, constraints on space, time, and preparation, and so on. This study was conducted to determine the readiness of physical education teachers at the University of Mindanao for ICT- assisted instruction. It used a quantitative, descriptive approach using descriptive statistics to determine the level of ICT literacy and ICT adoption of physical education teachers in teaching and learning. Complete enumeration was used to select the respondents. An online survey was administered to 35 qualified teachers from all branches of the University. The instruments used were adapted and improved from two different research projects. Three experts validated the test questionnaire and rubric in the field with a very good descriptive result. The data gathered were tallied and treated using the following statistical tools: the mean, standard deviation, and Pearson's r. Overall, results show that teachers' ICT literacy and ICT adoption were high. The study further indicates that physical education teachers are more likely to use ICT applications and resources such as the internet, multimedia computers, projector systems, PowerPoint presentations, or word processor programs, especially during teaching and learning sessions. Further, the researcher found that ICT literacy is positively correlated with ICT adoption. Implications of the study results were presented.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0870/a.php" alt="Hit counter" /></p>
TΗΕ PEDAGOGICAL ATTITUDE, DEALING AND MANAGING BEHAVIOR ISSUES IN THE MODERN SCHOOL: TRIBUTΙΟΝ TO THE TEACHER AND WRITER KOSTAS CHRISTAKIS
Authors: Fragkouli Aspasia 
Published: September 2024

In the context of the tribute to the author and professor Kostas Christakis, we focus on his books "Behaviour Problems of Children and Adolescents" and "Behaviour Problems in School Age" in order to discuss issues regarding the pedagogical attitude, as well as the treatment and management of students' behaviour issues in modern schools. The aim of this project is to highlight long-standing pedagogical issues around the prevention, assessment and treatment of behavioural difficulties of students in the school environment. The conclusions highlight the theoretical and practical pedagogical approaches and actions of teachers in the modern, inclusive school (Christakis, G. K., 2023, 2006).<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0721/a.php" alt="Hit counter" /></p>