bluuebunny/crossref_metadata_2025_split huggingface dataset:
Κοροναϊός του σκύλου: ένας όχι ‘αθώος’ ιός
Authors: NTAFIS (Β. ΝΤΑΦΗΣ) V. , PAPANASTASSOPOULOU (Μ. ΠΑΠΑΝΑΣΤΑΣΟΠΟΥΛΟΥ) M. , XYLOURI (E.ΞΥΛΟΥΡΗ) E. 
Published: February 2018

Canine coronavirus (CCoV) is a significant aetiologic agent of acute diarrhoea in dogs, specially in puppies. An important characteristic of coronaviruses is their high genetic variability, due to increased mutation frequency and sporadic recombination events. Due to this genetic variability, CCoV is classified in two distinct types, type I and II. CCoV type I strains share increased genetic similarity with Feline coronavirus strains, while CCoV type II consists of the typical reference CCoVs. Moreover, type II strains are classified into one of two subtypes, which include the classical strains (CCoV-IIa) and the new strains (CCoV-IIb), which emerged as a result of recombination among CCoV and Porcine transmissible gastroenteritis virus. Typical disease signs of CCoV infection are anorexia, depression, lethargy, as well as vomiting and diarrhoea. Mortality rate is low, especially in adult dogs with no infection signs. Most dogs recover within 7-10 days. Mixed infections with other viruses, bacteria or parasites may lead to more severe clinical disease. Currently, CCoV appears to have spread worldwide and has been related to mild, acute diarrhoea. However, during the last years, novel CCoV strains associated with outbreaks of lethal gastroenteritis have been detected in Australia and Europe. Genome analysis revealed that these strains shared low similarity with prototype reference strains of CCoV, suggesting that atypical, divergent strains may be related to more severe clinical signs. In addition, over the past decade, strains with an ability to trespass the intestinal tract, leading to lethal systemic infection, have also been isolated. These strains have attracted scientific interest, with research focusing on experimental infections, identification of genetic markers and prophylaxis. Pantropic CCoV strains have been detected across Europe, suggesting that the new, highly pathogenic biotype is circulating among canine population. The high genetic variability of CCoV, the severe mixed infections and the antigenic differences among CCoV types and subtypes raise questions regarding the protective efficacy of the currently commercially available vaccines.
Intestinal morphograhy of broilers fed diets supplemented with perlite
Authors: GHIASI GHALEHKANDI J. , HASSANPOUR S. , EBRAHIMNEHZAD Y. , BEHESHTI R. , MAHERI-SIS N. 
Published: February 2018

Aim of the study was to investigate effects of different levels of perlite on intestinal morphometry in broilers (Ross 308). A hundred and eighty broiler cockerels were randomly allocated into three experimental groups (3 replications and 20 broilers per pen) and fed experimental diets supplemented with different levels of perlite (0%, 2%, 4%). At 21, 28, 35 and 42 days of the study, 2 broilers were randomly selected from each replication, slaughtered and various sections of small intestine (1, 10, 30, 50, 70 and 90% of small intestine length) sampled for morphometry characteristics. Villi height, crypts depth and villus height / crypt depth ratio were measured microscopically. According to the results, a significant difference was observed on small intestine morphology post-perlite supplementation in experimental groups compared to control group. Supplementation of diet with perlite (2%) significantly increased average villi height in various sections of small intestine (1, 70 and 90%) in experimental birds on days 28 and 35 (P < 0.05). In addition, similar findings were observed after addition of perlite (4%) on villi height on day 42 (P <0.05). Furthermore, on day 28, average villi height and depth of liberkuhn crypts in small intestine (10%) differed significantly in cockerels fed diets containing 2% perlite in comparison to controls (P < 0.05). These results suggest that supplementation of perlite in broilers’ diet can improve intestinal morphometry.
Risk analysis factors for local recurrence in Ewing’s sarcoma
Authors: Albergo J. I. , Gaston C. L. L. , Parry M. C. , Laitinen M. K. , Jeys L. M. , Tillman R. M. , Abudu A. T. , Grimer R. J. 
Published: February 2018

Aims The aim of this study was to analyse a group of patients with non-metastatic Ewing’s sarcoma at presentation and identify prognostic factors affecting the development of local recurrence, in order to assess the role of radiotherapy. Patients and Methods A retrospective review of all patients with a Ewing’s sarcoma treated between 1980 and 2012 was carried out. Only those treated with chemotherapy followed by surgery and/or radiotherapy were included. Patients were grouped according to site (central or limb) for further analysis of the prognostic factors. Results A total of 388 patients were included in the study. Of these, 60 (15%) developed local recurrence at a mean median of 27 months (sd 24, range 7 to 150) and the five-year local recurrence-free survival (5yrLRFS) was 83%. For central tumours, the size of the tumour and histological response to chemotherapy were found to be significant factors for local recurrence. For limb tumours, local recurrence was affected by intralesional and marginal resections, but not by the histological response to chemotherapy. Radiotherapy in those with a marginal resection reduced the risk of local recurrence (5yrLRFS: 96% versus 81%, p = 0.044). Conclusion Local recurrence significantly affects the overall survival in patients with a Ewing’s sarcoma. For those with a tumour in a limb, radiotherapy reduced the risk of local recurrence, especially in those with a marginal margin of excision, but the effect in central tumours was less clear. Radiotherapy for those who have had a wide margin of resection does not reduce the risk of local recurrence, regardless of the histological response to chemotherapy. Cite this article: Bone Joint J 2018;100-B: 247–55.
The challenge of Monteggia-like lesions of the elbow
Authors: Jungbluth P. , Tanner S. , Schneppendahl J. , Grassmann J-P. , Wild M. , Hakimi M. , Windolf J. , Laun R. 
Published: February 2018

AimsThe aim of this retrospective multicentre study was to evaluate mid-term results of the operative treatment of Monteggia-like lesions and to determine the prognostic factors that influence the clinical and radiological outcome.Patients and MethodsA total of 46 patients (27 women and 19 men), with a mean age of 57.7 years (18 to 84) who had sustained a Monteggia-like lesion were followed up clinically and radiologically after surgical treatment. The Mayo Modified Wrist Score (MMWS), Mayo Elbow Performance Score (MEPS), Broberg and Morrey Score, and Disabilities of the Arm, Shoulder and Hand (DASH) score were used for evaluation at a mean of 65 months (27 to 111) postoperatively. All ulnar fractures were stabilized using a proximally contoured or precontoured locking compression plate. Mason type I fractures of the radial head were treated conservatively, type II fractures were treated with reconstruction, and type III fractures with arthroplasty. All Morrey type II and III fractures of the coronoid process was stabilized using lag screws.ResultsGood results were found for the MMWS, with a mean of 88.4 (40 to 100). There were 29 excellent results (63%), nine good (20%), seven satisfactory (15%), and one poor (2%). Excellent results were obtained for the MEPS, with a mean of 90.7 (70 to 100): 31 excellent results (68%), 13 good (28%), and two fair (4%). Good results were also found for the functional rating index of Broberg and Morrey, with a mean score of 86.6 (57 to 100). There were 16 excellent results (35%), 22 good (48%), six fair (13%), and two poor (4%). The mean DASH score was 15.1 (0 to 55.8). Two patients had delayed wound healing; four patients had nonunion requiring bone grafting. One patient had asymptomatic loosening of the radial head prosthesis.ConclusionMonteggia-like lesions are rare. With correct identification, classification, and understanding using CT scans followed by appropriate surgical treatment that addresses all components of the injury, good to excellent mid-term results can be achieved. Cite this article: Bone Joint J 2018;100-B:212–18.
Can next generation sequencing play a role in detecting pathogens in synovial fluid?
Authors: Tarabichi M. , Shohat N. , Goswami K. , Parvizi J. 
Published: February 2018

Aims The diagnosis of periprosthetic joint infection can be difficult due to the high rate of culture-negative infections. The aim of this study was to assess the use of next-generation sequencing for detecting organisms in synovial fluid. Materials and Methods In this prospective, single-blinded study, 86 anonymized samples of synovial fluid were obtained from patients undergoing aspiration of the hip or knee as part of the investigation of a periprosthetic infection. A panel of synovial fluid tests, including levels of C-reactive protein, human neutrophil elastase, total neutrophil count, alpha-defensin, and culture were performed prior to next-generation sequencing. Results Of these 86 samples, 30 were alpha-defensin-positive and culture-positive (Group I), 24 were alpha-defensin-positive and culture-negative (Group II) and 32 were alpha-defensin-negative and culture-negative (Group III). Next-generation sequencing was concordant with 25 results for Group I. In four of these, it detected antibiotic resistant bacteria whereas culture did not. In another four samples with relatively low levels of inflammatory biomarkers, culture was positive but next-generation sequencing was negative. A total of ten samples had a positive next-generation sequencing result and a negative culture. In five of these, alpha-defensin was positive and the levels of inflammatory markers were high. In the other five, alpha-defensin was negative and the levels of inflammatory markers were low. While next-generation sequencing detected several organisms in each sample, in most samples with a higher probability of infection, there was a predominant organism present, while in those presumed not to be infected, many organisms were identified with no predominant organism. Conclusion Pathogens causing periprosthetic infection in both culture-positive and culture-negative samples of synovial fluid could be identified by next-generation sequencing. Cite this article: Bone Joint J 2018;100-B:127–33.
Mid-term outcomes of routine proximal row carpectomy compared with proximal row carpectomy with dorsal capsular interposition arthroplasty for the treatment of late-stage arthropathy of the wrist
Authors: Gaspar M. P. , Pham P. P. , Pankiw C. D. , Jacoby S. M. , Shin E. K. , Osterman A. L. , Kane P. M. 
Published: February 2018

Aims The aims of this study were to compare the mid-term outcomes of patients with late-stage arthritis of the wrist treated with proximal row carpectomy (PRC) and dorsal capsular interposition (DCI) arthroplasty with a matched cohort treated with routine PRC alone. Patients and Methods A total of 25 arthritic wrists (24 patients) with pre-existing degenerative changes of the proximal capitate and/or the lunate fossa of the radius were treated with PRC + DCI over a ten-year period. This group of patients were matched 1:2 with a group of 50 wrists (48 patients) without degenerative changes in the capitate or lunate fossa that were treated with a routine PRC alone during the same period. The mean age of the patients at the time of surgery was 56.8 years (25 to 81), and the demographics and baseline range of movement of the wrist, grip strength, Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score, and Patient-Rated Wrist Evaluation (PRWE) score were similar in both groups. Results At a mean follow-up of 5.9 years (1.8 to 11.8), significant improvements in mean grip strength, the flexion-extension arc of movement of the wrist, QuickDASH, and PRWE scores were seen in both groups. There was no diifference between the groups for any of the outcomes. One patient in the PRC + DCI group required additional surgery for a deep infection, while two in the PRC group had complications (one wound dehiscence requiring revision closure, one transient radial sensory neuritis). One patient in each group required total arthrodesis of the wrist for progressive degenerative radiocarpal changes. A total of 70 patients (93%) were satisfied with the outcomes. Conclusion PRC with DCI is an effective form of treatment for late-stage arthritis of the wrist involving the capitolunate joint, with mid-term outcomes that are similar to those in patients without degenerative changes affecting the capitate or lunate fossa who are treated with a routine PRC alone. Cite this article: Bone Joint J 2018;100-B:197–204.
Assessing Character Strengths in Youth With Intellectual Disability: Reliability and Factorial Validity of the VIA-Youth
Authors: Shogren Karrie A. , Shaw Leslie A. , Raley Sheida K. , Wehmeyer Michael L. , Niemiec Ryan M. , Adkins Megan 
Published: February 2018

AbstractThis article reports the results of an examination of the endorsement, reliability, and factorial validity of the VIA–Youth and assessment of character strengths and virtues developed for the general population in youth with and without intellectual disability. Findings suggest that, generally, youth with intellectual disability endorsed character strengths as being like them at lower levels, although few differences were significant. Issues related to measurement, particularly the establishment of measurement invariance, emerged for some virtues. Reliability of the scale was similar across the two groups. Implications for future research and practice are discussed.
The Perceived Role of Direct Support Professionals in the Health Promotion Efforts of Adults With Developmental Disabilities Receiving Support Services
Authors: Leser Kendall A. , Pirie Phyllis L. , Ferketich Amy K. , Havercamp Susan M. , Wewers Mary Ellen 
Published: February 2018

Abstract
Direct support professionals (DSPs) play a large social role in the lives of people with developmental disabilities (DD) and have the potential to influence their health behaviors. Six qualitative focus groups (n = 48) were conducted with DD community agency administrators, DSPs, family members and adults with DD to better understand the perceived role of DSPs in the health promotion efforts of those with DD. Findings from this study suggest that DSPs experience several barriers when trying to promote the health of those with DD, one of which is fear of violating the rights of people with DD. Future work should identify ways to overcome the barriers experienced by DSPs, so that they can better assist people with DD with health promotion efforts.
Use of Transition Resources by Primary Care Providers for Youth With Intellectual and Developmental Disabilities
Authors: Dressler Paul B. , Nguyen Teresa K. , Moody Eric J. , Friedman Sandra L. , Pickler Laura 
Published: February 2018

AbstractYouth with intellectual and developmental disabilities (IDD) often experience difficulties with successful transition from pediatric to adult healthcare. A consultative Transition Clinic for youth with IDD was piloted as a quality improvement project, and assessed the engagement of primary care providers (PCPs) for transition planning after patients were seen in clinic. Although many PCPs found the clinic and resources useful, individual and systemic barriers often prohibited them from participating in transition planning for this patient population. These findings highlight systemic barriers that need to be addressed to ensure successful transition, as well as the need for a specialized Transition Clinic with involvement of specialists with expertise in IDD, such as Developmental-Behavioral Pediatrics, to assist throughout transition process.
Espacios de Formación Integral: transformaciones y desafíos para la enseñanza y la docencia de Ciencias Económicas y Administración
Authors: Castillo Jimena , Correa Natalia , Parentelli Varenka , Romero Melina 
Published: February 2018

Espacios de Formación Integral; Modalidades pedagógicas alternativas; Concepciones docentes; Desafíos en la docencia universitaria
The Effects of Dietary Whey Lactose and Lactobacillus Agilis Bacteria on the Growth Performance, Physicochemical Conditions of the Digestive Tract and the Caecal Microbial Ecology of Broiler Chickens
Authors: Szczurek Witold , Alloui Mohamed Nabil , Józefiak Damian 
Published: February 2018

Abstract
The principal goal of this study was to assess the responses of broiler chickens raised on floor litter to the 2% dietary level of lactose (LAC) originating from dried whey fed in combination with live culture of Lactobacillus agilis bacteria (90 million cells/kg diet) in terms of the performance and basic postslaughter parameters, the lumen pH in some alimentary tract segments, concentration of volatile fatty acids (VFA ) in the total (T) and undissociated (UD) forms and count of selected microbial populations in the caeca determined by fluorescent in-situ hybridisation (FISH). A parallel aim was to evaluate the outcomes from the combined supplementation in comparison with feeding of LAC and the L. agilis bacteria as separate dietary supplements. Six hundred and forty Ross 308 chickens were placed in 16 floor pens (40 birds per pen having equal sex ratio) and were provided with free access to the feed (a mash maize-wheat-soybean meal-based diet) and water. Dietary treatments provided from day 8 to 42 of age were: LAC-free basal diet (CON), LAC-containing diet (CON + LAC), LAC-free diet with the addition of L. agilis (CON + BAC) and LAC-containing diet with addition of L. agilis (CON + LAC + BAC). The LAC supplementation caused significant decreases in the luminal pH of the crop, ileum and caeca, and the addition of the L. agilis bacteria reduced the pH in the crop and caeca. The overall concentration of total (T) volatile fatty acids was higher in the caeca of broilers receiving the LAC-containing diets. Both the LAC and the BAC supplements, independently from one another, resulted in significantly greater caecal levels of UD acetate, propionate and butyrate. The FISH analysis revealed that counts of Bacteroides sp./Prevotella sp. group were higher after the inclusion of LAC in the feed. All three dietary supplementations significantly reduced the total counts of the family Enterobacteriaceae and decreased the number of naturally occurring C. perfringens bacteria compared with the basal control diet (CON). Neither LAC inclusion nor BAC addition to the diet affected the counts of the Clostridium coccoides/Eubacterium rectale group. The synergistic effects of the simultaneous supplementation of LAC and L. agilis were found on the T butyrate concentration and on C. perfringens and the Enterobacteriaceae counts. No improvements in the body weight gains and post-slaughter traits were observed due to uncombined and combined supplementation with 2% LAC and L. agilis, indicating that the shifts in composition of the caecal microbiota toward a healthier composition by using these additives were not large enough to create the positive growth rate and processing yields responses in broilers maintained in a litter-floor environment.
Relations Among Poor Sleep, Anxiety and Depression Among the Students of Health Sciences
Authors: Jurgita Andruškienė , Šarūnė Barsevičienė , Asta Mažionienė , Akvilė Virbalienė 
Published: February 2018

AbstractThe research in the area of health sciences students’ sleep quality and mood disorders is lacking in Lithuania, as well as other European countries. The aim of this study was to compare prevalence of poor sleep, anxiety and depression among the students according to the study programmes and to assess the relations among poor sleep, depression and anxiety. The study sample consisted of 672 Klaipeda State University of Applied Sciences students (95.5% were female), from 18 to 46 years of age. Sleep quality was evaluated by Pittsburgh Sleep Quality Index, anxiety by Hospital Anxiety and Depression Scale, sociodemographic questions were used. The chi-square test or Fisher exact test was used to estimate association between categorical variables. P-values less than 0.05 were interpreted as statistically significant. Poor sleep was more prevalent among Beauty Therapy (26.4%, 95% CI 22.2-30.56) and Nursing (21.3%, 95% CI 17.42 – 25.17) students, as compared with persons studying in Oral Health programmes (14.8%, 95% CI 11.46 – 18.17), p<0.05. Depression mean score was higher in Beauty Therapy students (4.76), as compared to Oral Health (3.69) students, p<0.05. Beauty Therapy (9.99) or Physiotherapy students (8.24) had higher anxiety mean score, as compared to Oral Health students (7.14), p<0.05. Anxiety mean score was significantly higher (8.45) among the ones with disturbed sleep, as compared to normally sleeping students (5.86), p<0.001. Depression mean score (4.77) was higher among the students having disturbed sleep, as compared to the students which sleep was not disturbed (2.87), p<0.001. Poor sleep and anxiety were more prevalent among the students aged 20 years and older as compared to the students, aged 18 and 19 years. Second and third year students more often had poor sleep or anxiety as compared to the first-year students. Poor sleep and anxiety were more common among Beauty Therapy and Physiotherapy students than among Oral Health Students. Among the students who slept poorly, symptoms of anxiety and depression were statistically significantly more frequent than those students whose sleep was not disturbed. Depression and anxiety mean scores were statistically significantly higher among the students who had poor sleep, as compared to the ones who had normal sleep, in all age and year of studying groups.
Malik Ṣadr al-Dīn Tabrīzī and the Establishment of Mongol Rule in Iran
Authors: Zakrzewski Daniel 
Published: February 2018

Abstract
Malik Ṣadr al-Dīn Tabrīzī (d. 668/1269–70) was one of the most important individuals to the establishment of Mongol rule in Iran. His biography illustrates like few others not only themes of mobility and cross-cultural contacts across Eurasia but also the importance of local elites to the formation of the empire of Chinggis Khan and his descendants. Malik Ṣadr al-Dīn belonged to a notable family of Tabriz and served as governor of his native city soon after the definitive Mongol conquest of 628/1231. He traveled to Mongolia in 649/1251 and was put in charge of implementing a revised imperial taxation system in northwestern Iran by Great Khan Möngke. Then Malik Ṣadr al-Dīn remained a key player in the financial administration of the emerging Ilkhanate as Möngke’s brother Hülegü asserted his claims to the northwestern core area of Mongol Iran against his enemies from the house of Jochi. Despite connections of Malik Ṣadr al-Dīn’s family to the Jochids, he continued as governor of Tabriz where he also acted as a patron of Persian literature until his death. So far Malik Ṣadr al-Dīn has gone almost unnoticed in historical scholarship.
From the West to the East, from the Sky to the Earth: A Biography of Jamāl al-Dīn
Authors: Yang Qiao 
Published: February 2018

Abstract
Jamāl al-Dīn (Zhamaluding 札馬魯丁 d. ca.1289) is probably the most successful and best-documented Muslim astronomer who was active in the Mongol Yuan court. He migrated from Central or West Asia to China and introduced Islamic astronomical, geographical and cartographic knowledge into China. In spite of his high official position and the honorable titles that were granted to him, his biographic information in Chinese sources is scattered, and there is uncertainty in identifying him in non-Chinese sources. This paper attempts to reconstruct Jamāl al-Dīn’s life and activities by an in-depth reading and interpretation of the biographic information, supplementing and enriching it with biographies of Jamāl al-Dīn’s contemporary astronomers in the Mongol Empire. This article argues that Jamāl al-Dīn achieved success and honor due to his knowledge in various fields that interested the Mongols, his correct reading of the imperial ideology and the political map, and the extensive social networks he built for himself during the decades he lived in China.