bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catch-slip behavior observed upon rupturing membrane-cytoskeleton bonds
Authors: Rajasekharan Vivek , Sreenivasan Varun K. A. , Pereira Fred A. , Farrell Brenda 
Published: September 2017

AbstractCells are capable of cytoskeleton remodeling in response to environmental cues at the plasma membrane. The propensity to remodel in response to a mechanical stimulus is reflected in part by the lifetime of the membrane-cytoskeleton bonds upon application of a tensile loading rate. We measure the lifetime and force to rupture membrane-cytoskeleton linkages of a head and neck squamous cell carcinoma (HNSCC) cell line, HN-31 by applying a tensile loading rate (< 60 pN/s) with a handle bound to a cell, while monitoring the displacement of the handle at 2 kHz after averaging. We observe the lifetime increases with loading rate,rfto a maximum after which it decreases with further increase inrf. This biphasic relationship appears insensitive to drugs that target microtubule assembly, but is no longer detectable, i.e., lifetime is independent ofrfin cells with reduced active Rho-GTPases. The loading rate-time relationship resembles catch-slip behavior reported upon applying tensile loads to separate protein complexes. Under small loads the bonds catch to increase lifetimes, under larger loads their lifetime shortens and they dissociate in a slip-like manner. Our data conforms to a model that considers the membrane-cytoskeleton bonds exhibit a load-dependent conformational change and dissociate via two pathways. We also find the membrane-cytoskeleton linkages strengthen with stationary compressive load,FSC(|FSC| < 40 pN), and conclude this metastatic cell line responds to small mechanical stimuli by promoting cytoskeleton remodeling as evident by observing F-actin within the membrane nanotube (10 µm length) formed after bond rupture.
Tissue specific auxin biosynthesis regulates leaf vein patterning
Authors: Kneuper Irina , Teale William , Dawson Jonathan Edward , Tsugeki Ryuji , Palme Klaus , Katifori Eleni , Ditengou Franck Anicet 
Published: September 2017

SummaryThe plant hormone auxin (indole-3-acetic acid, IAA) has a profound influence over plant cell growth and differentiation. Current understanding of vein development in leaves is based on the canalization of auxin into self-reinforcing streams which determine the sites of vascular cell differentiation. However, the role of auxin biosynthesis during leaf development in the context of leaf vein patterning has not been much studied so far. Here we characterize the context specific importance of auxin biosynthesis, auxin transport and mechanical regulations in a growing leaf. We show that domains of auxin biosynthesis predict the positioning of vascular cells. In mutants that have reduced capacity in auxin biosynthesis, leaf vein formation is decreased. While exogenous application of auxin does not compensate the loss of vein formation in auxin biosynthesis mutants, inhibition of polar auxin transport does compensate the vein-less phenotype, suggesting that the site-specific accumulation of auxin, which is likely to be mainly caused by the local auxin biosynthesis, is important for leaf vein formation. Our computational model of midvein development brings forth the interplay of cell stiffness and auxin dependent cell division. We propose that local auxin biosynthesis has the integral role in leaf vascular development.HighlightsBuilt spatially and temporally resolved auxin biosynthesis map in growing leaf primordium of Arabidopsis.Expression domains of auxin biosynthetic enzymes within primordia strongly correlated with leaf vein initiation.Results show that domains of auxin biosynthesis within primordia drive leaf vein initiation and patterning.Highlights and eTOC BlurbUsing modelling and a spatiotemporal analysis of auxin biosynthesis and transport, Kneuper et al. show that tissue specific auxin biosynthesis defines places of vein initiation hence underlining the importance of auxin concentration in vein initiation.
The Perceptual Shaping of Anticipatory Actions
Authors: Maffei Giovanni , Herreros Ivan , Sanchez-Fibla Marti , Friston Karl J. , Verschure Paul F.M.J. 
Published: September 2017

ABSTRACTHumans display anticipatory motor responses to minimize the adverse effects of predictable perturbations. A widely accepted explanation for this behavior relies on the notion of an inverse model that, learning from motor errors, anticipates corrective responses. Here, we propose and validate the alternative hypothesis that anticipatory control can be realized through a cascade of purely sensory predictions that drive the motor system, reflecting the causal sequence of the perceptual events preceding the error. We compare both hypotheses in a simulated anticipatory postural adjustment task. We observe that adaptation in the sensory domain, but not in the motor one, supports the robust and generalizable anticipatory control characteristic of biological systems. Our proposal unites the neurobiology of the cerebellum with the theory of active inference and provides a concrete implementation of its core tenets with great relevance both to our understanding of biological control systems and, possibly, to their emulation in complex artefacts.
Spatial difference analysis of residential energy consumption, income and carbon emissions in China
Authors: Ding Yongxia , Niu Shuwen 
Published: September 2017

Purpose
This paper aims to analyze the internal relationships and tendency of residential energy consumption, income and carbon emissions.

Design/methodology/approach
Taking 30 provinces of China as the analysis unit and dividing them into two types of urban and rural consumer groups, the panel data model was built. In addition, panel unit root test, panel cointegration test and panel Granger causality test were also used.

Findings
The results showed that there are long-run equilibrium relationships between the three variables, which show the regular tendency in the spatial process. The elasticity coefficients of residential energy consumption and CO2 emissions vary across the three regions and decline continuously from the western to central and eastern regions. In addition, geographic location is also an important factor on the energy consumption and CO2 emissions in residential sector.

Originality/value
This paper provides some points for policies on cutting energy use and pollution in residential sector.
Job separation rates of immigrants and natives in the UK during the Great Recession
Authors: Papoutsaki Dafni 
Published: September 2017

Purpose
The purpose of this paper is to assess the probability of job separations of immigrants and natives in the UK before and during the economic crisis of 2008.

Design/methodology/approach
A mixed proportional hazard duration model with a semi-parametric piecewise constant baseline hazard is used on a data sample of inflows into employment.

Findings
It is found that the crisis increased the probability of exits to unemployment for all groups, while immigrants from the new countries of the European Union seemed to have the lowest hazard towards unemployment even after controlling for their demographic and labour market characteristics. More specifically, even when we account for the fact that they tend to cluster in jobs that are most vulnerable to the business cycle, they are still less likely to exit dependent employment than natives. However, this migrant group is adversely affected by the crisis the most.

Research limitations/implications
Possible implications of out-migration of the lower performers are discussed.

Originality/value
This paper makes use of the panel element of the UK Quarterly Labour Force Survey, and uses duration analysis on the individual level to assess the labour market outcomes of natives and immigrants in the UK.
How immigrants helped EU labor markets to adjust during the Great Recession
Authors: Kahanec Martin , Guzi Martin 
Published: September 2017

PurposeThe economic literature starting with Borjas (2001) suggests that immigrants are more flexible than natives in responding to changing sectoral, occupational and spatial shortages in the labor market. The purpose of this paper is to study the relative responsiveness to labor shortages by immigrants from various origins, skills and tenure in the countryvis-à-visthe natives, and how it varied over the business cycle during the Great Recession.Design/methodology/approachUsing data primarily from the EU Labor Force Survey and the EU Statistics on Income and Living Conditions, the authors calculate a wage-based measure of labor shortages in the first stage while in the second stage the authors use them in a first-differences fixed-effects model as a regressor to explain changes in immigrants’ distribution across sectors, occupations and countriesvis-à-visthe natives.FindingsThe authors show that immigrants have responded to changing labor shortages across EU member states, occupations and sectors at least as much and in many cases more flexibly than natives. This effect is especially significant for low-skilled immigrants from the new member states or with the medium number of years since migration, as well as with high-skilled immigrants with relatively few (one to five) or many (11+) years since migration. The relative responsiveness of some immigrant groups declined during the crisis years (those from Europe outside the EU or with 11 or more years since migration), whereas other groups of immigrants became particularly fluid during the Great Recession, such as those from new member states.Research limitations/implicationsThe results suggest that immigrants may play an important role in labor adjustment during times of asymmetric economic shocks, and support the case for well-designed immigration policy and free movement of workers within the EU. Some limitations include alternative interpretations of the wage premium as our measure of shortage, as well as possible endogeneity of this measure in the model.Originality/valueThe results provide new insights into the functioning of the European Single Market and the roles various immigrant groups play for its stabilization through labor adjustment during the times of uneven economic development across sectors, occupations and countries.
Morbidity differential among emigrants’ and non-emigrants’ wives in Kerala, India
Authors: Ali Imtiyaz , Bhagat Ram B. , Shankar Geetika , Verma Raj Kumar 
Published: September 2017

Purpose
The purpose of this paper is to analyze the overall morbidity prevalence and their differentials among emigrants’ and non-emigrants’ wives in Kerala, India.

Design/methodology/approach
The study is based on the third round of The Kerala Migration Survey-2007 data. The third round of KMS was perhaps the first survey which has collected data on Indian emigration and morbidity scenario during 2007 at the household and individual level. Descriptive statistics, binary logistic regression models, and Oaxaca decomposition models were used to examine the disease differentials among emigrants’ and non-emigrants’ wives.

Findings
The paper shows that household size is negatively associated with chronic disease and incidence of morbidity is much lower among emigrants’ wives. The result also shows that among women, those who stay with a husband or whose husbands are elsewhere in India show a higher incidence of morbidity than those whose husbands are abroad, owing to the limited scope of activity as well as freedom in lifestyle and for taking independent decisions. Thus, it can be concluded that for women, the scope of activity and the freedom to live are important factors contributing to the level of morbidity. Blinder-Oaxaca decomposition results show that non-poor households and non-Muslim religion are in a disadvantageous position in terms of chronic morbidity.

Research limitations/implications
This paper is based on the cross-sectional nature of data; this is an obvious limitation on the effect of emigration on morbidity differentials among emigrants’ and non-emigrants’ wives.

Originality/value
There are few or rare studies conducted so far to investigate the effect of migration on the health of the spouses or families left behind.
Private attribute inference from Facebook’s public text metadata: a case study of Korean users
Authors: Choi Daeseon , Lee Younho , Kim Seokhyun , Kang Pilsung 
Published: September 2017

Purpose
As the number of users on social network services (SNSs) continues to increase at a remarkable rate, privacy and security issues are consistently arising. Although users may not want to disclose their private attributes, these can be inferred from their public behavior on social media. In order to investigate the severity of the leakage of private information in this manner, the purpose of this paper is to present a method to infer undisclosed personal attributes of users based only on the data available on their public profiles on Facebook.

Design/methodology/approach
Facebook profile data consisting of 32 attributes were collected for 111,123 Korean users. Inferences were made for four private attributes (gender, age, marital status, and relationship status) based on five machine learning-based classification algorithms and three regression algorithms.

Findings
Experimental results showed that users’ gender can be inferred very accurately, whereas marital status and relationship status can be predicted more accurately with the authors’ algorithms than with a random model. Moreover, the average difference between the actual and predicted ages of users was only 0.5 years. The results show that some private attributes can be easily inferred from only a few pieces of user profile information, which can jeopardize personal information and may increase the risk to dignity.

Research limitations/implications
In this paper, the authors’ only utilized each user’s own profile data, especially text information. Since users in SNSs are directly or indirectly connected, inference performance can be improved if the profile data of the friends of a given user are additionally considered. Moreover, utilizing non-text profile information, such as profile images, can help increase inference accuracy. The authors’ can also provide a more generalized inference performance if a larger data set of Facebook users is available.

Practical implications
A private attribute leakage alarm system based on the inference model would be helpful for users not desirous of the disclosure of their private attributes on SNSs. SNS service providers can measure and monitor the risk of privacy leakage in their system to protect their users and optimize the target marketing based on the inferred information if users agree to use it.

Originality/value
This paper investigates whether private attributes of SNS users can be inferred with a few pieces of publicly available information although users are not willing to disclose them. The experimental results showed that gender, age, marital status, and relationship status, can be inferred by machine-learning algorithms. Based on these results, an early warning system was designed to help both service providers and users to protect the users’ privacy.
Consumer acceptance of mobile payment across time
Authors: Wu Jinnan , Liu Lin , Huang Lihua 
Published: September 2017

Purpose
Although perceived risk and usefulness have been identified as two major factors that influence consumer acceptance of an innovative mobile payment (m-payment), relatively few researchers have explored the impact of affective factors on perceived risk and usefulness, and the relationship between perceived risk and usefulness. Also, it is unclear whether there is a difference in the acceptance intention among users across different diffusion stages of this innovation. The purpose of this paper is to investigate the role of positive emotion in consumer acceptance of WeChat payment across time.

Design/methodology/approach
This study proposed and validated a framework integrating the consumer response system model and the affect heuristic. A total of 484 valid responses were collected through two online surveys at two diffusion stages of WeChat payment technology. The structural equation modeling and multigroup analysis were used to test the hypotheses.

Findings
The results show that users’ acceptance intention is relatively related to perceived risk, perceived usefulness, and positive emotion. Positive emotion has a strong negative impact on perceived risk and a positive impact on perceived usefulness. Also, perceived usefulness strongly decreases users’ perception of risk. Multigroup analyses find that both positive emotion and perceived risk have significant positive and negative impacts on acceptance intention at the stage of market introduction rather than market growth. Rather, the influence of positive usefulness on acceptance intention is significantly higher at the stage of market growth than at market introduction.

Originality/value
This study indicates that exploring the role of positive emotion and the moderating effect of diffusion stages in m-payment acceptance provides a more comprehensive understanding of how to achieve a greater acceptance rate of an innovative m-payment.
Strategic hybrid lateral transshipment for cost-optimized inventory management
Authors: Nakandala Dilupa , Lau Henry , Zhang Jingjing 
Published: September 2017

Purpose
Logistics practitioners must continually improve inventory management processes as they daily respond to the twin drivers of customer satisfaction and cost efficiency. The purpose of this paper is to investigate the scenario of sourcing goods through lateral transshipments in a periodic-review policy setting, against a backdrop of cost optimization objectives.

Design/methodology/approach
The authors develop decision rules that make cost-optimized selection between backordering and combined reactive and proactive lateral transshipment options possible. This necessarily takes account of the trade-off between purchasing, holding and backorder cost components. In addition, the authors use simulation studies to illustrate the superior performance of the proposed decision options.

Findings
According to results of the simulation studies, the proposed two-step decision rule generates the lower inventory cost than the alternative decisions rules. The outperformance of proposed two-step decision rule is valid in different scenario.

Practical implications
This study develops the decision rules to assist wholesaler logistics practitioners to make optimized decisions with regard to whether they should proactively lateral transshipments and if selected, the optimum size of the extra lateral transshipment.

Originality/value
This study has made a significant contribution to the existing knowledge base as it develops decision rules for a combined proactive and reactive approach using lateral transhipments to meet both urgent demand and a part of the demand expected during the supplier lead time in a cost-efficient way.
Barriers to third-party logistics integration: empirical evidence from China
Authors: Huo Baofeng , Wang Qianwen , Zhao Xiande , Hua Zhongsheng 
Published: September 2017

PurposeThe purpose of this paper is to investigate effects of two integrative mechanisms of third-party logistics (3PL) integration (i.e. information sharing and process coordination) between users and providers on relationship satisfaction, and further explores how partnership-surrounding (e.g. legal unprotectability) and partnership-specific barriers (e.g. measurement difficulty and cooperation difficulty) influence 3PL integration in the context of Chinese 3PL practices.Design/methodology/approachUsing data collected from 247 3PL users in China, this study uses the structural equation modeling method to empirically examine the relationship among partnership-surrounding/specific barriers, 3PL integration and relationship satisfaction.FindingsThe results show that information sharing has no significant effect on relationship satisfaction, while process coordination has a positive effect on relationship satisfaction and partially mediates the relationship between information sharing and relationship satisfaction. Furthermore, as partnership-specific barrier, measurement difficulty and cooperation difficulty are negatively related to information sharing and process coordination. Surprisingly, as partnership-surrounding barrier, legal unprotectability is not significantly related to information sharing but is positively related to process coordination.Originality/valueAs a comprehensive study on 3PL user-provider relationship in China, this study extends existing 3PL literature by providing evidence about the importance of 3PL integration and different types of barriers to 3PL integration, also providing managerial implications for 3PL users, providers, law and regulation makers about how to better implement 3PL integration in China.
Strategic characterization of process assets based on asset quality and business impact
Authors: Sanchez-Segura Maria-Isabel , Ruiz-Robles Alejandro , Medina-Dominguez Fuensanta , Dugarte-Peña German-Lenin 
Published: September 2017

Purpose
The purpose of this paper is to present the strategic intangible process assets characterization (SIPAC) methodology illustrated by an example of its application to the field of information technology (IT). This is a pioneering methodology for characterizing the impact and quality of intangible process assets and intellectual capital as levers to achieve organizational objectives. This strategic intellectual capital approach will help to identify both intangible assets and indicators geared to meeting organizational objectives. This is of vital importance since the success of an organization can be construed in terms of goal achievement.

Design/methodology/approach
The paper illustrates an example of the step-by-step application of the proposed methodology at an IT company. The aim is to describe its use in a real case so that other companies can benefit from the replication of the methodology used.

Findings
The proposed methodology (SIPAC) that the authors have designed and applied has been found to be useful and provide an insightful new point of view for strategic decision making in the IT industry taking into account intangible process assets.

Practical implications
The proposed methodology has been exemplified in a real case. This should help organizations to use the methodology to replicate the results.

Originality/value
Each and every organization has know-how represented by intangible assets. This paper meets an identified need to use intangible process assets as levers to help organizations achieve their business goals.