bluuebunny/crossref_metadata_2025_split huggingface dataset:
SINYAL TRANSDUKSI DARI BROMELAIN SEBAGAI ANTIINFLAMASI PADA UDEMA TELAPAK KAKI TIKUS YANG DISEBABKAN OLEH KARAGEN
Authors: Sudjarwo Sri Agus 
Published: January 2017

The signal transduction of bromelain as antiinflamatory in carragenan-induced rat paw edema were investigated. SpragueÂ Dawley Rats were divided into the control groups which were given saline, and bromelain groups which received doses ofÂ 10, 20 and 40 mg/kg bromelain (peroral) respectively. This was followed by the administration of 1 % caragenin throughÂ the intraplantar route 30 min after administration Â bromelain or saline. After the carrageenan injection paw volume,Â prostaglandin (PGE2) production and cyclooxigenase (COX)-1 and COX-2 expression was measured. The bromelain inÂ doses of 10, 20 and 40 mg/kg showed 11.3; 45.1 and Â 56.3 % inhibition of paw edema respectively at the Â end of threeÂ hours. The increase in Prostaglandin (PGE2) levels after carrageenan injection was significantly prevented byÂ preadministration of the bromelain at 20 and 40 mg/kg but not bromelain at 10 mg/kg. Bromelain a dose-dependentÂ inhibited both COX-1and COX-2 activity in carrageenin-induced inflammation. Bromelain inhibited COX-2 Â than COX-1Â stronger activity. These results suggest that antiinflammatory effect of bromelain is due to its ability to inhibit PGE2production could be mediated by inhibition mainly on COX-2 than COX-1 activity.Â Keywords: Bromelain, Cyclooxigenase, Prostaglandin
KEMAMPUAN SEL LIMPA NORMAL MENCEGAH TERJADINYA PENYAKIT AUTOIMMUNE PADA MENCIT IL-2RÎ² Î²Î² Î² -/-
Authors: Rifaâ€™i Muhaimin 
Published: January 2017

Adoptive transfer is a potentially curative treatment for both inherited and acquired diseases of hematopoieticÂ compartment and organ failure. The aim of this experiment was to know the potency of normal unfractionated spleen cellsÂ to prevent pathological autoimmunity in IL-2RÎ²-/-mice. Here, we show that the normal unfractionatedspleen cells have aÂ capacity to prevent autoimmune diseases when adoptively transferred to IL-2RÎ²-/-Â mice. Intravenously, and adoptivelyÂ transferred of normal unfractionated spleen cells (107) to IL-2RÎ²-/-mice (3 wks) gave an evidence on preventing the lethalÂ phenotype due to autoimmune disease in IL-2RÎ²-/-mice. The donor cells have a capacity to reverse the status of recipientÂ cells from memory to naÃ¯ve type. In addition, donorcells also have a capacity to regulate the development of granulocyteÂ cells into normal level of homeostasis. These findings suggest that normal unfractionated spleen cells Â could in the futureÂ be used in clinical settings to cure autoimmune diseases.Â Keywords :autoimmune, spleen cells, IL-2RÎ²-/-, mice
PERUBAHAN KADAR SITOKIN DAN MOLEKUL AGREGASI PADA BERBAGAI TINGKAT TROMBOSITOPENIA PADA DEMAM BERDARAH DENGUE
Authors: Djunaedi Djoni 
Published: January 2017

The uncovering of the changes in the concentration of aggregation molecules (vWF, PGI2) and cytokines (TNFÎ±, IL-1Î²,Â IL-6) in different levels of thrombocytopenia in DHF patients can be used as the basis in predicting the occurrence ofÂ thrombocytopenia. A prospective-observational studywas undertaken utilizing a 3-day sequentially drawn vein blood ofÂ inclusive DHF patients. The TNFÎ±, IL-1Î² and IL-6 test was conducted utilizing the quantikine high sensitivity humanÂ cytokine immunoassay, and the vWF and PGI2test was conducted utilizing the ELISA procedure. Â The multivariate andÂ discriminant analyses tests on the deltas between day 1 and 2 observations, and between day 2 and 3 observations ofÂ the 6 variables showed Wilksâ€™ Lambda =0.638 with p=0.008 and platelets and vWF as the most powerful discriminatingÂ variable (70.5.%). The findings of this study indicated that in DHF patients (1) the changing of the concentration of TNFÎ±,Â IL-1Î²and IL-6 cytokines do not play a significant role Â in the mechanism of platelets aggregation, (2) platelets countÂ decreases in a condition in which vWF facilitated platelets aggregation, (3) the changing of a positive contribution of vWFÂ causes a determination of the process of platelets aggregation, and (4) a positive changing of vWFâ€™s concentration can beÂ used as a prognostic indicator of a negative changing of platelets count..Â Key words: Dengue Hemorrhogic Fever, thrombocytopenia, vWF
SKOR KEBOCORAN VASKULER SEBAGAI PREDIKTOR AWAL SYOK PADA DEMAM BERDARAH DENGUE
Authors: Setiati Tatty Ermin , Retnaningsih Anastasia , Supriatna Mohmad , Soemantri Agustinus 
Published: January 2017

The prediction of shock in Dengue Hemorrhagic Fever is difficult to made, hence, is difficult to detect Â shock as early asÂ possible. This results in delayed management and ultimately can cause death. Serum levels of protein, albumin,Â hematocrit, and PEI which are markers of vascular leakage hoped to be able to be used as predictor of Â shock in DHF.Â The aim of this study was to develop a scoring system, the Vascular Leakage Score (VLS) that could be used as theÂ predictor of shock and to define the probability ofshock from each total score. This was a cross-sectional, observationalÂ analytic study, in RSDK, Semarang from 2001-2003. The samples were 138 children with DHF, aged 3-14 years old,Â divided into 52 cases of DHF without shock, and 76 cases of Dengue Shock Syndrome. Serum levels of protein, albumin,Â PEI, and hematocrit were obtained at admission. Then, a classification was made upon the four parameters mentionedÂ above, based on the ROC curve analysis from the previous studies, and based on the WHOâ€™s criteria. To develop aÂ formula for VLS, we gave points-weight for each parameter to calculate the Î²-coefficient, then continued with calculationÂ of DSS probability based on total combination of the four categories above, using a logistic-regression analysis ofÂ multivariate.
HUBUNGAN KADAR SENG SERUM DENGAN TINGGI BADAN ANAK SEKOLAH DASAR PENDERITA GAKY
Authors: Setijowati Nanik 
Published: January 2017

The incidence goiter starts to the extend in Urban area. Not all Elementary School children with goiterexperience ofÂ pursued growth. This indicates that besides low iodine content, there are other elements which also influence growth.Â This research intends to study the relationship between zinc the level of serum and height on elementary school childrenÂ (8 â€“ 12 year) in endemic goitre areas, in Malang Municipality. Data ware collected with cross-sectional study from AugustÂ to December 2000. Blood and urine sample of twenty Â children of each group were examined for zinc serumand iodineÂ urine concentration. Information about diet pattern, socio-economical condition were obtained by structured questionairreÂ for mother and children.This research used Independent T-test, Person Correlation test, and Multiple Regression forÂ statistics analysis. The result showed that: (1). There were significant relationships between energy (r= 0.364, p = 0.012);Â protein (r = 0.481, p = 0.001) and zinc intake (r =0.491, p = 0.001) with height; (2). There were significant difference inÂ energy (p = 0.014), carbohydrate (p = 0.042), lipid( p = 0.014), protein (p = 0.003), and zinc intake(p = 0.004) betweenÂ the two groups examined. The conclusion was that lower height for age was possibly ascribed to lack of energy, protein,Â iodine and zinc intake.Â Key words:zinc serum, iodine urine, height for age, and goiter
PERANAN MAKROFAG PADA PROLIFERASI, DIFERENSIASI DAN APOPTOSIS PADA PROSES HEMATOPOISIS (PENELITIAN PADA LIMPA JANIN TIKUS DAN ASPIRAT SUMSUM TULANG MANUSIA)
Authors: Widjajanto Edi 
Published: January 2017

Macrophage stimulates growth of surrounding cells by various cytokines and growth factors synthesized Â and eliminateÂ apoptotic cells by its phagocytes activity. This study was to evaluate the evidence of macrophage as regulator cells duringÂ haematopoiesis. Haematopoietic activity assessed microscopically by proportion of various haematopoietic blood cells toÂ total nucleated blood cells on imprint preparation of fetal ratus (Wistar) spleen and human marrow aspirate, after Wrightâ€™sÂ stain coloration. Fetal ratus spleen and human marrow aspirate were used to evaluate macrophage as a stimulator cellÂ and suppressor cell respectively. During prenatal period, the proportion of macrophage increased at 14thdays (1.3 Â±Â 0.9%), 16thdays (7.6 Â± 1.8 %), 18thdays (12.9 Â± 2.8 %) and 20thdays prenatal gestation periods (14.1 Â± 3.1%). Thismacrophage increment was associated with the increase of other blood cells, except the proportion of lymphoid cell whichÂ decreased. During postnatal period the macrophage proportion decreased (11.0 Â± 1.7 %), and other bloodcellsÂ proportion continuously increased except lymphoid cells which decreased. Many haematopoietic islands representingÂ active haematopoietic process were found at 14thdays of fetal rat spleen. Macrophage in human hypocellular marrow (n =Â 9) increased and it exceed other blood cells proportion (29 %, p < 0.001) and contained phagocytosed apoptotic bodies.Â This study concludes that high macrophage regulates Â haematopoiesis when it was proportionally low and regulateÂ haematopoiesis when it was proportionally high.Â Keywords:Macrophage, Apoptosis, Haematopoiesis
HUBUNGAN KADAR GULA DARAH SAAT MASUK RUMAH SAKIT DENGANCARDIAC EVENTS PADA PENDERITA INFARK MIOKARD AKUT DI RS DR SARDJITO YOGYAKARTA
Authors: Irawan Bambang , Suharno Suharno , Rochmah Wasilah 
Published: January 2017

Hyperglycaemia is common in patients with acute myocardial infarction with and without diabetes mellitus. There is aÂ positive relationship between hyperglycaemia at thetime of event and highly incidence of mortality and morbidity afterÂ acute myocardial infarction. Consequently, understanding the possible mechanisms through which hyperglycaemiaÂ worsens the prognosis of acute myocardial infarction, as well as effectiveness of its control during acute myocardialÂ infarction, seems to be a great relevance. This study to investigate wether a relationship exists between blood glucoseÂ level on admission and cardiac events in non diabetic patients after an acute myocardial infarction. Method, Â a cohortÂ prospective observational study was done on acute myocardial infarctionâ€™s patients who were hospitalized in ICCU DRÂ Sardjitoâ€™s hospital from March 2002 until October 2004. Subject who met inclusion and exclusion criteria were divided intoÂ 2 groups, the group in which blood glucose level onadmission was â‰¤ 140 mg/dl and the group with bloodglucose onÂ admission was > 140 mg/dl. Cardiac events as well as mortality, cardiac failure, reinfarction and cardiogenic shock wereÂ observed for 6 months. There were 95 subjects, 93 males and 2 females.
PROTEIN FIMBRIA 16 kDa BAKTERI ACINETOBACTER BAUMANNIIDARI URIN PENDERITA INFEKSI SALURAN KEMIH BERPERAN SEBAGAI PROTEIN HEMAGLUTININ DAN ADHESIN
Authors: Noorhamdani Noorhamdani 
Published: January 2017

Acinetobacter baumannii (Acb) is an opportunistic and nosocomial pathogen that ussualy found in clinical specimen fromÂ patients with intensive care. The pathogenic mechanism of this bacteria are not fully elucidated especially potentialÂ activity of its protein as hemaglutinin and adhesion molecul. The aim of this study is to evaluate the Â role of 16 kDaÂ fimbriae protein from urnary tract infection (UTI) patient as hemaglutinin and adhesion molecule. Usingexplorative designÂ this study was started by isolation Acb bacteria from urine of patient that had been determine as UTI clinically andÂ laboratory. After identification this bacteria by microbact system hemaglutination test and isolation Â of its fimbriae fraction,Â 12.5% SDS-PAGE had been used to isolated fimbriae protein, following assay in vitro to adhesion test..The studyÂ showed that the 16 kDa fimbriae protein of Acb bacteria was a hemaglutinin protein that could agglutinate 0.5% miceÂ erythrocytes (1/32), and human blood group O erythrocytes (1/8). Hemaglutination test were negative onerythrocytesÂ from rat, guinea pig, sheep, and human blood group A, B. The 16 kDa fimbriae protein (AF16) was also adhesion proteinÂ that had been revealed by its activity to adherenceto receptor of mice enterocytes. The increasing dose of AF16Â molecules will decrease the amount of Acb bacteria to adherence to enterocytes (p<0.05). The fimbriae of Acb is maybeÂ classified P type.Â Key words:Acinetobacter baumannii, fimbriae, hemaglutinin protein, adhesion protein
PENGARUH CURCUMIN TERHADAP KADAR KOLESTEROL TOTAL, LDL-KOLESTEROL, JUMLAH F2 -ISOPROSTAN, DAN SEL BUSA (FOAM CELL) DINDING AORTA PADA TIKUS DENGAN DIET ATEROGENIK
Authors: Fikriah Ika , Kalim Handono , Dradjat Respati Suryanto 
Published: January 2017

ABSTRACTÂ Death Â caused Â by Â cardiovascular Â and Â cerebrovascular diseases Â are Â still Â the Â highest. Â Atherosclerosis Â due Â toÂ hypercholesterolemia is a predispositioning factor of both diseases. Curcumin has an antioxidant character that can inhibitÂ lipid peroxidase to atherogenesis process. The aim of this study was to observe the effect of curcumin in decreasing totalÂ cholesterol level, LDL-cholesterol, the number of Â F2-isoprostan and foam cell of aortaâ€™s wall of white rats strain wistarÂ after giving atherogenic diet for 10 weeks. There were 6 groups in this study (n=24): atherogenic diet group (group I asÂ positive control), atherogenic diet group + curcumin 50 mg/kg b.w. per day (group II), atherogenic diet group + curcuminÂ 100 mg/kg b.w. per day (group III), atherogenic diet group + curcumin 200 mg/kg b.w. per day (group IV), atherogenic dietÂ group + curcumin 400 mg/kg b.w. per day (group V), normal diet group (group VI as negative control). After 10th, the levelÂ of total cholesterol and LDL-cholesterol were measured by spectrofotometri. Staining F2-isoprostan was done with AvidinÂ Biotin Complex imunohystochemistry method, and staining foam cell with HE-oil Red O. The number of Â F2-isoprostanÂ and foam cells were counting semi quantitatively using Â light microscope. The highest total cholesterol level was found inÂ group I (275,15 Â± 10,01; Mean Â± SD), the highest LDL-cholesterol level was found in group I (158,15 Â± 12,19).Â Statistically total cholesterol level and LDL-cholesterol level in group I were significantly higher (p â‰¤ 0,05) than other
HUBUNGAN ANTARA PENINGKATAN KADAR LEKOTRIEN B4 (LTB-4) DENGAN HIPOSELULARITAS SUMSUM TULANG (PENELITIAN PADA ASPIRAT SUMSUM TULANG)
Authors: Widjajanto Edi 
Published: January 2017

ABSTRACTÂ Previous study on human bone marrow culture showed that leukotrien B-4 (LTB-4) which was added to granulocyte-macrophage and erytroid colony, suppressed the growth of colonies. This study assessed the correlation between LTB-4Â and marrow cellular. Marrow aspirate which was taken from 60 adult patients (26 men and 34 women) suffering fromÂ various haematopoietic problems was examined for amount of LTB-4 and the degree of marrow cellular. ELISA principleÂ was applied for LTB-4 measurement and marrow cellular assessed by counting the member of nucleated cells per cubic-mm of marrow aspirate using microscopic counting chamber principle. Existing difference of the strength of correlation ofÂ LTB-4 Â and Â marrow Â cellular Â was Â analized Â using Â manova and Â path Â analysis Â and Â expressed Â as Â path Â coefficient.TheÂ difference of confounding factors such as gender, age and type of diseases (haematopoitic problems) were controlled andÂ homogenized during statistical analysis using SPSS 10 program. Path coefficient in the multi cellular marrow (n = 60) wasÂ â€“ 0.092 (p = 0.495) and path coefficient in hypo cellular marrow (n = 28) was â€“ 0.406 (p = 0.013). This study concludesÂ that the increase of amount of LTB-4 in hypo cellular marrow is associated with the decrease of marrow cellular.Â Keywords : Leukotrien B-4, Hypocelular marraw, Apoptosis, Hematopoisis
VAKSINASI BCG MENINGKATKAN AKTIVITAS FAGOSITOSIS DAN SEKRESI REACTIVE OXYGEN INTERMEDIATE (ROI) PADA MAKROFAG PERITONEUM KUCING YANG DIINFEKSI DENGAN Mycobacterium tuberculosis
Authors: Tjahajati Ida 
Published: January 2017

ABSTRACTÂ The aim of this experiment was to study the effect of BCG vaccination on phagocyte activity and ROI secretion in catÂ peritoneum macrophages which infected with M.tuberculosis. The experiment used twenty four healthy cats. The animalsÂ were divided in 2 groups, 12 cats in each group. Group I were vaccinated with BCG, group II were control group whichÂ unvaccinated. BCG vaccination was done twice in two weeks interval. Two days after vaccination each cat was infectedÂ by 105Â cfu M.tuberculosis intraperitoneally. The activity of macrophages were measured Â at 1st, 2nd, 12th, and 24th, afterÂ infection using in vitro latex bead phagocyte and NBT reduction assay. Three cats were used to measure the macrophageÂ activity in each period, using triplicate sample for each cat. The results of the experiment showed that the phagocyteÂ activity and ROI secretion increased significantly in vaccination group (P<0.01) compared with the control group, andÂ these activities reached to the plateau level at 2 weeks after infection. Although these enhanced activities were graduallyÂ diminished thereafter, higher levels of these activities were consistently observed until the end of experiment comparedÂ with control group. BCG vaccination increased the cellular immunity especially phagocyte and ROI secretion activities ofÂ peritoneual macrophages in cat infected with M.tuberculosisÂ Key words: BCG, phagocyte, ROI, M.tuberculosis, cat
PENINGKATAN KADAR LEPTIN DENGAN PUFA (Polyunsaturated Fatty Acid) MELALUI AKTIVASI PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR gamma (PPARÎ³) PADA KULTUR PREADIPOSIT KELINCI
Authors: Indra Muhammad Rasjad 
Published: January 2017

ABSTRACTÂ For the past three decades, PUFA has been recognized as importnant energy sources and cell membrane component.Â PUFA also plays key roles in many cellular events such as gene regulation and leptin activation. The role of this fatty acidÂ is still unknown especially in vitro. The purpose of this research was to examine the effect of PUFA of the corn oil inÂ increasing leptin concentration by PPARÎ³ activation. Preadipocyte culture from rabbit was incubated by PUFA of corn oil.Â PUFA have been given on doses 0, 4, 8 and 16 ÂµM. PPARÎ³ protein and leptin levels were analyzed by ELISA. PPARÎ³Â expression Â was Â analyzed Â by Â immunocytochemistry. Â The research Â result Â showed Â that Â every Â treatment Â has Â increasedÂ PPARÎ³ levels inconsistently. PPARÎ³ concentration increased significantly on 4 ÂµM PUFA treatment compared to control,Â 8 and 16 ÂµM PUFA of corn oil. But there were no significant difference between control and 8 ÂµM PUFA treatments.Â Leptin levels increased significantly between administration on 4 ÂµM PUFA and 16 ÂµM PUFA of corn oil administration.Â Leptin levels was not significantly different between control and 8 ÂµM PUFA. There was also strong correlation betweenÂ PPARÎ³ expression and leptin levels. PUFA of corn oil increases leptin levels through PPARÎ³ activation.Â Key words: PUFA, preadipocyte, leptin, PPARÎ³
PERBANDINGAN ANTARA PEMBERIAN ASAM FOLAT, EKSTRAK GINKGO BILOBA, DAN METHYL COBALAMIN TERHADAP INDEKS APOPTOSIS DAN EKSPRESI CASPASE 3 PADA INTOKSIKASI METANOL SEL GANGLION RETINA
Authors: Prayitnaningsih Seskoati , Sumarno Sumarno 
Published: January 2017

ABSTRACTÂ Permanent Â visual Â damage Â caused Â by Â methanol Â intoxication Â has Â been Â associated Â with Â prolonged Â exposures Â to Â bloodÂ formate Â concentrations. Â Formate Â accumulation Â disrupt Â mitochondrial Â energy Â production, Â which Â subsequently Â lead Â toÂ caspase 9, 3 activation and finally causes apoptosis. Â Folic acid (FA) has been used as adjunctive therapy to enhance theÂ rate Â of Â formate Â metabolism. Â Extract Â Ginkgo Â biloba Â (EGb) Â the Â most Â popular Â herbal Â therapy Â possess Â is Â antioxidant Â andÂ antiapoptotic capacity. On the other hand, Methyl cobalamin, a kind of endogenous co enzyme B 12 can promote nucleicÂ acid and protein synthesis. To compare the effect of FA, (EGb), and Methyl Cobalamin (MC) to Apoptotic Index (AI) andÂ Caspase 3 expression of Â retinal ganglion cell induced by methanol intoxication (MI). Experimental study was conductedÂ in Pharmacology and Biomedic laboratory of Brawijaya University for two weeks. Fifteen rats were included, and dividedÂ into five groups: (a) control, (b) Methanol Intoxication only, (c) Folic Acid 1 mg day per os, (d) Extract Ginkgo biloba 50Â mg/kb Â per Â os, Â and Â (e) Â Methyl Â Cobalamin Â 500 Â microgram/kg Â intraperitoneally Â for Â three Â days. Â MI Â were Â done Â by Â givingÂ methanol 4 g/kg in the first day, and 2 g/kg for two days after. Apoptotic Index and Caspase 3 expression were assessed
MANIFESTASI KLINIS DAN LABORATORIS PENDERITA SINDROMA GUILLAIN BARRE DI RUANG PERAWATAN ANAK RSU DR. SAIFUL ANWAR MALANG
Authors: Muid Masdar 
Published: January 2017

ABSTRACTÂ Guillain Barre Syndrome is one of the leading diseases from Acute Flaccid Paralysis after the decrease in poliomyelitis. InGuillain Barre Syndrome, the motoric muscles becomes weak and it could also attack the respiratory muscle which is lifethreatening to patients. The objective of this study is to report Guillain Barre Syndrome cases from June 1999 until June2005 based on the clinical manifestation and laboratory in children care unit of dr. Saiful Anwar hospital. In this researchthere were 38 Guillain Barre Syndrome cases which were diagnosed using the Gilroy and Meyer criteria. 22 patients(57,9%) Â were Â male, Â 16 Â patients Â (42,1%) Â were Â female. Â 18 Â patients Â (43,36%) Â were Â below Â 5 Â years Â of Â age, Â 13 Â patients(34,21%) were between 5 to 10 years of age and 7 patients (18,42%) were between the age of 10 to15 years. The mostcommon infection that precedes was upper respiratory infenction which amounts to 32 cases (84,21%). The latent phasebetween 8 to 14 days were 11 patients (28,94%) and 15 to 21 days were 22 patients (57,89%). The progresive phase 1 to7 days occured in 17 patients (44,73%), 8 to 14 days also in 17 patients (44,73%).The clinical features were paresthesiasfollowed by weakness to 23 patients (60,52%) and weakness only in 15 patients (39,47%). The pattern of weakness bytetraparese Â in Â 5 Â patients Â (13,15%) Â and Â paraparese Â in Â 33 Â patients Â (86,84%). Â The Â distribution Â of Â weakness Â was Â more
FAKTOR-FAKTOR YANG MELATARBELAKANGI MOTIVASI SESEORANG UNTUK MENGGUNAKAN SUNTIKAN SILICONE CAIR DI MALANG TAHUN 2001
Authors: Asmika Asmika , Chuluq Chusnul , Sutrisnani Catur Suci 
Published: January 2017

ABSTRACTÂ Recently it has been reported that some women have suffered from illness complication as the effect of the use the liquidÂ silicone to beautify themselves. Knowledge deprivation and eagerness to achieve complete beauty in an easy and cheapÂ way makes them undertake a short cut which is getting the injection. The research is intended to know some factorsÂ underlying a personâ€™s motivation to use liquid silicone injection in Malang in 2001. The research was a descriptive crossÂ sectional method. The population was person who use liquid silicone injection in Malang 2001, this assume were 20Â persons during the research (June â€“ December 2001). This research showed that 15 respondents (75 %) of the samplesÂ knew the benefits of liquid silicone injection but did not know the effect of the injection, the education of this respondentsÂ were secondary and tertiary level 13 respondents (65 %), 6 respondents (30 %) of the sample working as beauticians, 6Â respondents (30 %) of the samples having salary Â Rp. 250.000,00 - Rp.500.000,00 per month, Â 9 respondents (45 %) ofÂ the samples feeling more beautiful and self confident after getting liquid silicone injection, 6 respondents (30 %) of theÂ samples getting family permission, 12 respondents (60 %) of the samples having a social network to use the injection, 5Â respondents (25 %) of the samples getting secondary health services and 4 respondents (20 %) of the samples getting