bluuebunny/crossref_metadata_2025_split huggingface dataset:
A hipertrofia adenoideana e sua relação com distúrbios psiquiátricos e neurocognitivos em uma população pediátrica
Authors: Leite Daniel Tinôco , Guércio Wilson Benini , Luz Natália Maria Câmara da , Barone Marcelo Monteiro Vieira Braga , Guércio Janine Oliveira Santos , Ribeiro André Costa Pinto 
Published: September 2024

Introdução: A hipertrofia adenoideana é a causa mais comum de obstrução das vias aéreas superiores em crianças e pode ser facilmente tratada por adenoidectomia. Nessa população, a respiração oral pode implicar em diferentes tipos de distúrbios do sono, instabilidade emocional, disfunção neurocognitiva, hiperatividade, transtornos de conduta, dentre outras alterações psiquiátricas. Objetivo: Avaliar a prevalência dos transtornos psiquiátricos e neurocognitivos em crianças e adolescentes submetidos a adenoidectomia e analisar as características clínico-epidemiológicas dessa população. Material e Métodos: Estudo transversal, de prevalência, em que participaram pacientes submetidos a adenoidectomia no Hospital Universitário da Universidade Federal de Juiz de Fora (HU-UFJF), entre março de 2021 e dezembro de 2023. Resultados: Foram incluídos 102 pacientes com a média de idade de 8,78 anos, com desvio padrão de ±3,16 anos. Todos os pacientes possuíam indicação cirúrgica, sendo que 22,5% deles possuíam previamente diagnóstico de algum transtorno psiquiátrico ou do neurodesenvolvimento. O transtorno mais prevalente foi o transtorno do déficit de atenção com hiperatividade (TDAH), representando 30,4% do total da amostra com diagnóstico prévio. A prevalência dos transtornos foi similar em ambos os sexos, sendo 11,8% no sexo masculino e 10,8% no sexo feminino. Discussão: Neste estudo, o TDAH foi o distúrbio mais prevalente, representando 30,4% dos pacientes com diagnóstico de algum transtorno prévio à cirurgia. A adenoidectomia, quando realizada em crianças com obstrução acentuada da via aérea superior, beneficia o padrão respiratório e pode melhorar a atenção, os distúrbios comportamentais, as funções cognitivas, além de diminuir a necessidade do uso de medicações psiquiátricas comparativamente com o quadro clínico pré-operatório. Conclusão: Os distúrbios psiquiátricos e neurocognitvos têm prevalência importante na população pediátrica com hipertrofia adenoideana. Tais distúrbios devem ser sempre investigados nesse grupo de pacientes e, em caso de confirmação diagnóstica, um tratamento multidisciplinar deve ser instituído.
Royalty Rate as Industry Invariant in IP Transactions and Litigation
Authors: Костин А.В. 
Published: September 2024

В статье показана фундаментальная роль отраслевых ставок роялти в лицензионных договорах и аналитического метода их расчета. Аналитический метод расчета ставок роялти (RoS - Royalty on Sales price) на основе рентабельности продаж (ROS) и прибыли до вычета процентов и налогов (EBIT - Earnings Before Interest and Taxes) отличается высокой точностью и учитывает специфику отраслей, в которых используется объект интеллектуальной собственности. Этот метод широко применяется как в судебных экспертизах, так и в коммерческих сделках, охватывая расчеты убытков, оценку рыночной стоимости исключительных прав, а также определение размеров компенсации и вознаграждения авторам в различных юрисдикциях. Показано, что ставка роялти является ключевым элементом двухкомпонентного ценообразования в лицензионных сделках, обеспечивая гибкость и эффективность в управлении интеллектуальной собственностью.
The article demonstrates the fundamental role of industry royalty rates in licensing agreements and the analytical method for their calculation. The analytical method for calculating royalty rates (RoS - Royalty on Sales price) based on Return on Sales (ROS) and Earnings Before Interest and Taxes (EBIT) is highly accurate and takes into account the specifics of the industries where the intellectual property is used. This method is widely applied both in forensic examinations and in commercial transactions, covering loss calculations, market value assessments of exclusive rights, as well as determining compensation and remuneration for authors in various jurisdictions. It is shown that the royalty rate is a key element of two-component pricing in licensing deals, providing flexibility and efficiency in intellectual property management.
Sequenciamento de próxima geração: novas tecnologias para acessar às comunidades microbianas
Authors: Santana Filho Djalma Moreira 
Published: September 2024

Os sequenciadores de próxima geração, do inglês Next-Generation Sequencing (NGS), são plataformas capazes de gerar milhões de dados de sequências de DNA ou RNA em uma só rodada através da clonagem in vitro, técnica utilizada para incrementar o número de moléculas e permitir a análise. Mas é necessário agrupar informações que deem ao pesquisador condições de decidir qual melhor metodologia adotar. Logo, o objetivo desse artigo foi realizar um estudo de revisão de literatura abordando tecnologias de NGS, compará-las entre si e a métodos mais comuns, mostrando sua importância em microbiologia agrícola e ambiental. O método de Sanger é o principal método de obtenção de sequências conhecido atualmente. Mas, a metodologia adotada pelas plataformas NGS utilizam abordagens que dinamizam o sequenciamento; e o avanço das técnicas vem reduzindo consideravelmente os custos do sequenciamento. Para realizar os estudos foram utilizados dados de artigos e das plataformas das empresas detentoras das tecnologias, realizando-se comparações e análises sobre o tema. Por isso, a pesquisa é de cunho bibliográfico e este artigo caracteriza-se como artigo de revisão de literatura. Várias plataformas de sequenciamento de próxima geração estão disponíveis no mercado, mas são de alto custo e estão restritas a alguns países. Ainda há dificuldade de encontrar algoritmos adequados para analisar a quantidade de dados (sequências) gerados, mas apesar disso os métodos de NGS vêm criando boas expectativas e prometem avanços importantes em estudos com a finalidade de acessar e identificar os grupos que compõem a estrutura da comunidade microbiana em pesquisas ambientais.
GeneXpert Assay in Detection of Pulmonary Tuberculosis and Rifampicin Tuberculosis Resistant in Tehsil Hazro Population; A Cross Sectional Study
Authors: Mehmood Shaukat , Pervaiz Farrah , Mahmood Humaira , RIAZ MEHWISH , Khan Javeria , Diba Farrah 
Published: September 2024

Objective: To determine the prevalence of Tuberculosis and MDR Tuberculosis by GeneXpert assay in Tehsil Hazro District Attock.
Study design: cross sectional study
Place and duration of study: Study was carried out at THQ hospital Hazro of District Attock from January 2019 to December 2020
Patients and Methods: Total 1460 patients of TB suspect were included in the study. First LED microscopy of all TB suspects was done. LED Microscopy positive cases along with suspects having history of HIV, close contacts of MDR TB, all TB cases of retreatment and sputum-negative cases of LED microscopy having positive clinical findings were sent for GeneXpert Assay. Results from the GeneXpert assay were categorized as GeneXpert positive, GeneXpert negative, and MDR Tuberculosis. Determinants of MDR- TB were identified using questionnaires regarding MDR –TB.
Results: Out of total 205 patients on GeneXpert Assay, 43 patients were GeneXpert positive test with no rifampicin resistance, 3 patients were GeneXpert positive with rifampicin resistance and 63 patients were GeneXpert negative but sign and symptoms, X-ray findings and laboratory tests were supporting tuberculosis and according to opinion of TB specialist they were labeled as Sputum negative Tuberculosis. Tuberculosis prevalence in Tehsil Hazro was 0.073. From the results, it was concluded that an overall MDR rate was 2.7% in our study population.
Conclusion: GeneXpert Assay is a rapid technique and reliable for Mycobacterium detection. The main determinants of MDR-TB were the patients who had contact h/o with MDR cases and those who did not follow the treatment regime in their previous Tuberculosis treatment.

Keywords: GeneXpert Assay, LED microscopy, MDR Tuberculosis, Sputum positive TB, Sputum negative TB.
AVALIAÇÃO BIOMECÂNICA E INTERVENÇÕES ERGONÔMICAS PARA A PREVENÇÃO DE DISTÚRBIOS OSTEOMUSCULARES RELACIONADOS AO TRABALHO
Authors: Cunha Leilane Lira da , Castro Gerlane Carvalho , Sá Alisson de Souza , Lopes Bruna Karen Diniz , Medeiros Letícia Pinto Gondim , Filho Ricardo Ernesto Machado , Gondim Medeiros Chaves Fabiola , Silva Thais Bednarczuk da , Silva Thainara Pereira Da , Lima Jefferson Raimundo de Almeida , Ferreira Douglas da Rocha , Cunha Ítalo Iris Boiba Rodrigues da 
Published: September 2024

Introdução: A crescente incidência de distúrbios osteomusculares relacionados ao trabalho (DORT) tem destacado a necessidade urgente de abordagens eficazes para a prevenção desses problemas. Esses distúrbios, muitas vezes causados por esforços repetitivos e posturas inadequadas, impactam negativamente a saúde dos trabalhadores e comprometem a produtividade. Objetivos: Identificar e analisar os principais fatores biomecânicos e ergonômicos que contribuem para a ocorrência de distúrbios osteomusculares no ambiente de trabalho. Materiais e Métodos: Para a obtenção de dados, foram empregados os recursos dos seguintes repositórios: Base de Dados em Scientific Electronic Library Online (SCIELO), PubMed e Literatura Latino-Americana do Caribe em Ciências da Saúde (LILACS). Uma variedade de fontes, incluindo artigos científicos, monografias e periódicos, foi examinada para extrair informações pertinentes sobre o assunto. Resultados e Discussões: A avaliação biomecânica revelou que os principais fatores de risco para distúrbios osteomusculares foram posturas inadequadas e movimentos repetitivos, frequentemente observados em atividades específicas. A análise identificou que a ausência de pausas regulares e a falta de adaptações no ambiente de trabalho contribuíam significativamente para o desenvolvimento desses distúrbios. A discussão destaca que, ao integrar avaliações biomecânicas com intervenções ergonômicas, foi possível mitigar os fatores de risco associados aos DORTs. A abordagem ergonômica demonstrou ser eficaz na redução dos sintomas e na prevenção de novas ocorrências, evidenciando a importância de um ambiente de trabalho adaptado às necessidades dos trabalhadores para promover uma saúde ocupacional duradoura. Conclusão: O estudo confirmou que a combinação de avaliações biomecânicas e intervenções ergonômicas é eficaz na prevenção de distúrbios osteomusculares relacionados ao trabalho. As análises destacaram que a adaptação do ambiente de trabalho e a implementação de práticas ergonômicas apropriadas resultaram em uma redução significativa dos sintomas e na melhoria da saúde dos trabalhadores. Estes achados reforçam a importância de adotar estratégias preventivas e ergonômicas para promover um ambiente de trabalho mais seguro e saudável, minimizando o impacto dos DORTs e melhorando a qualidade de vida dos funcionários.
Upgrading the evolutionary approach to the study of forced oscillations in a resonator
Authors: Erden F. 
Published: September 2024

UDC 517.9
We investigate the possibility of upgrading of the evolutionary approach to solving vector initial-boundary-value problems for the Maxwell equations and solve the equation of forced oscillations in a cylindrical resonator by using the upgraded approach. In addition, the potential for extending the approach to the theory of laser dynamics is discussed.
A source of semiprimeness on inverse and completely regular semigroups
Authors: Mekera Rasie , Yeşil Didem 
Published: September 2024

UDC 512.5
We define

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S
S

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-inverse semigroup and

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S
S

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-completely regular semigroup structures that are not encountered in the literature and are studied in our work for the first time. The properties of these new semigroup types and their relations with the other semigroup types, such as

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S
S

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-idempotent,

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S
S

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-regular,

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S
S

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-nonzero, and

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S
S

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-reduced semigroups, are discussed. Further, the relationship between the source of semiprimeness and the semiprime ideal is analyzed. It is also shown that the intersection of all semiprime ideals is equal to the source of semiprimeness. Moreover, if a function is surjective, then it can be shown that the analyzed two structures are preserved under homomorphism.
A DNA barcode reference library for the Tipulidae (Insecta, Diptera) of Germany
Authors: Fahldieck Moritz , Rulik Björn , Thormann Jana , Mengual Ximo 
Published: September 2024

Tipulidae, commonly known as true crane flies, represent one of the most species-rich dipteran families, boasting approximately 4,500 known species globally. Their larvae serve as vital decomposers across diverse ecosystems, prompting their frequent and close observation in biomonitoring programs. However, traditional morphological identification methods are laborious and time-consuming, underscoring the need for a comprehensive DNA barcode reference library to speed up species determination.
In this study, we present the outcomes of the German Barcode of Life initiative focused on Tipulidae. Our DNA barcode library comprises 824 high-quality cytochrome c oxidase I (COI) barcodes encompassing 76 crane fly species, counting for ca. 54% of the German tipulid fauna. Our results significantly increased the number of European tipulid species available in the Barcode of Life Data System (BOLD) by 14%. Additionally, the number of barcodes from European tipulid specimens more than doubled, with an increase of 118%, bolstering the DNA resource for future identification inquiries.
Employing diverse species delimitation algorithms — including the multi-rate Poisson tree processes model (mPTP), Barcode Index Number assignments (BIN), Assemble Species by Automatic Partitioning (ASAP), and the TaxCI R-script — we successfully match 76-86% of the morphologically identified species. Further validation through neighbor-joining tree topology analysis and comparison with 712 additional European tipulid barcodes yield a remarkable 89% success rate for the species identification of German tipulids based on COI barcodes.
This comprehensive DNA barcode dataset not only enhances species identification accuracy but also serves as a pivotal resource for ecological and biomonitoring studies, fostering a deeper understanding of crane fly diversity and distribution across terrestrial landscapes.
The Future of Referencing Specimens Is Near: Cite the Digital Specimen DOI
Authors: Addink Wouter , Theocharides Soulaine 
Published: September 2024

Specimens are often mentioned in scholarly publications or data infrastructures by referencing the local identifiers attached to the objects held in specimen collections. However, these are often only unique to the issuing institution and not resolvable. Transforming these into globally unique identifiers, such as the 'Darwin Core Triplet' constructed from codes that specify the institution, the collection and the accession or catalog number, is an imperfect solution. These cannot be unambiguously validated nor be dereferenced (Guralnick et al. 2015, Groom et al. 2019), are vulnerable to human error, and rely on accession numbers that sometimes change over time. Earlier approaches to give specimens globally unique and resolvable identifiers had limited success (Page 2009). Attaching labels with new identifiers is too costly and time consuming, apart from digital infrastructure challenges.
The Digital Extended Specimen is a new object on the internet, containing all known information about the specimen, thus acting as a surrogate for the physical object. To distinguish it from its physical counterpart, it needs a new identifier, which also provides a solution to unambiguously and persistently refer to specimens. Digital specimens get Digital Object Identifiers (DOIs) and Persistent Identifiers, in the infrastructure developed in the BiCIKL project (see deliverable D7.1 and this blog post). Ties to these accession or catalog numbers of physical specimens, allow these local identifiers to change over time, while still persistently resolving to the digital object.
DOIs guarantee global uniqueness, persistence and reliable resolution through the oversight of the DOI Foundation and its registration agencies (RAs). DiSSCo, Distributed System of Scientific Collections, is creating a partnership with DataCite RA, where both partners invest to provide Digital Specimen DOIs and enhance their findability, leveraging from their metadata services. This aids the potential of Digital Specimen DOIs to reliably create links with data in other infrastructures, cite individual specimens, and improve the FAIR-ness (Findable, Accessible, Interoperable, Reusable) of specimen data worldwide. We will present how to use these new DOIs in practice.
The use of Digital Specimen DOIs in a publication to reference a specimen is already piloted (Deeleman-Reinhold et al. 2024). All specimen records cited in the publication have been assigned a DOI that points to a digital representation of the specimen, the Digital Specimen, which can evolve over time to become a digital extended specimen by digitally linking it to relevant ecological, environmental, and related data such as the publication itself. The DOIs redirect both to a machine readable and a human readable version and include metadata in the DOI record for machine actionability that is also findable in DataCite Commons. The Crosscite citation formatter offers guidance to users how to cite a Digital Specimen DOI, similar to DOIs that refer to other works.
COVID-19 Pandemic Effects on Angler Effort and a Brown Trout Population in a Driftless Area Stream in Southeast Minnesota
Authors: Dieterman Douglas J. 
Published: September 2024

Abstract
Early opinions of the COVID-19 pandemic included equivocal notions of whether the pandemic would result in more or less angler effort and harvest in recreational fisheries. Early papers also suggested using changes in angling license sales to infer changes in angler effort but expressed concern about adequate assessment of pandemic effects on fisheries because of interruptions to routine assessment programs. To assess pandemic effects on angler effort at a stream trout fishery, a trail camera was installed immediately prior to implementation of a statewide stay-at-home order, at a representative stream trout angling site that is part of a long-term fish monitoring program. The trail camera was deployed through the trout harvest angling season from the peak pandemic year of 2020 through cessation of most restrictions in 2022. Statewide sales of angling licenses and trout stamps were assessed through this time to compare with angler effort measured with the trail camera. Annual trout population assessments were examined for pandemic effects in conjunction with angler effort. Anglers were present on 84% of days in 2020, 66% in 2021, and 69% in 2022. Following the pandemic peak of 603 angler-hours in 2020, angler-hours declined by 23% between 2020 and 2021 and by –16% between 2020 and 2022, whereas statewide sales of licenses and trout stamps only declined by 4% between 2020 and 2021 and 11% between 2020 and 2022, suggesting more angler pressure at the study site than could be inferred by changes in license or trout stamp sales. Higher pressure during the pandemic was due in part to more anglers younger than 20 years old. Despite higher angler pressure in 2020, there was no long-term effect on the Brown Trout population, as adult abundance in 2021 and 2022 exceeded abundance in every year from 2017 to 2020. These data add to a limited number of similar field-based pandemic studies coupling changes in angler use with fish population responses and should provide further insight into the broader assessment of COVID-19 pandemic effects.
Clinical learning of nursing students during the COVID-19 pandemic in Limpopo province, South Africa
Authors: Nchabeleng Linda , Bopape Mamare A. , Manamela Ledile E. , Ntho Tshepo A. 
Published: September 2024

Background: The Nursing Education Programme was affected during the coronavirus disease 2019 (COVID-19) pandemic, resulting in nursing students being unable to participate in the clinical experiential learning required by the South African Nursing Council.Objectives: The study seeks to explore and describe nursing students’ experiences of clinical experiential learning during the COVID-19 pandemic.Method: A qualitative, explorative and descriptive, research design was used in the study. A non-probability purposive sampling method was used, and 55 nursing students participated in the study. Data were collected through six focus group discussions, consisting of 8–12 nursing students in each group. Data were analysed following Tesch’s open coding method.Results: Three themes emerged from the study’s findings: The impact of COVID-19 on the clinical experiential learning of nursing students, the effects of COVID-19 on the mental well-being of nursing students, and nursing students’ experiences of support during the COVID-19 pandemic. Notably, 11 sub-themes emerged.Conclusion: The findings of this study reveal that the COVID-19 pandemic severely disrupted the Nursing Education Programme, highlighting the challenges of inadequate clinical hours, restricted clinical access and the significant psychological impact on students.Contribution: This study adds to the literature on students’ experiences during clinical experiential learning in South Africa during the COVID-19 pandemic.
Evaluation Recovery of Ulcerative Colitis with a Lactobacillus Cocktail Derived from Traditional Dairy Products: In vivo Study
Authors: Rezai Shaghayegh , Ghorbani Elnaz , Khazaei Majid , Nazari Seyedeh Elnaz , Rahmani Farzad , Naimi Hamideh , Afshari Asma , Avan Amir , Ryzhikov Mikhail , Soleimanpour Saman , Mehr Seyed Mahdi Hasanian 
Published: September 2024

Background:
This investigation investigates the anti-inflammatory and fibrinolytic effects of a cocktail of probiotics derived from traditional dairy products in a murine model of ulcerative colitis (UC).

Materials and Methods:
A mix of newly isolated probiotics containing L. plantarum, L. brevis, L. delbrueckii, and L. helveticus was characterized and orally administered to inbred eight-week-old C57BL/6 male mice (n = 6). Clinical symptoms, pathohistological changes, and inflammatory and fibrosis markers were analyzed in the existence and absence of probiotics in colitis mice.

Results:
Dairy lactobacillus probiotics potently attenuated colitis symptoms by decreasing dextran sulfate sodium (DSS)-induced body weight loss, colon shortening, rectal bleeding, and rectal prolapse. Consistently, a cocktail of probiotics could significantly improve histopathological grading by suppressing crypt loss, mucosal damage, and inflammation scores in colitis tissues. Moreover, the mix of probiotics suppressed pro-inflammatory genes including interleukin (IL)-1β, IL-6, tumor necrosis factor-alpha (TNF-α), and interferon-gamma (IFN-γ), and increased anti-oxidant markers and activity such as superoxide dismutase and catalase in colon tissue. Furthermore, compared to the no-treated group, the administration of probiotics reduced fibrosis by decreasing collagen deposition in tissue sections and down-regulating levels of pro-fibrotic genes including alpha-actin-2 (Acta2), collagen (Col) 1a1, and Col 1a2 in colitis tissue homogenates.

Conclusions:
The results show the newly isolated cocktail of probiotics elicits a potent protective effect on UC symptoms in mice model. Further study on these probiotics is required to fully explore their effectiveness, strength, and safety considerations.