bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Serenoa repens Alcohol Extract on Benign Prostate Hyperplasia
Authors: Saidi Skender , Stavridis Sotir , Stankov Oliver , Dohcev Sasho , Panov Sasho 
Published: October 2017

Abstract
An increasing tendency has recently emerged for the use of phytotherapeutic agents as alternative to commercial pharmacological agents for the treatment of benign prostate hyperplasia (BPH). The purpose of this study is to evaluate the effects of Serenoa repens alcohol extract treatment on BPH patients’ symptoms and major parameters during one-year follow-up.
The study was performed on 70 men aged 40 - 79 years (mean 60.58) with symptomatic BPH that were divided into a group of 40 patients treated with Serenoa repens extract (SRT) and a control group of 30 patients that received no treatment and were observed only. The following parameters were determined at the time of diagnosis (baseline), and after 6 and 12 months: prostate size, serum prostate-specific antigen (PSA) and uroflowmetry parameters including maximum flow rate (MFR), average flow rate (AFR) and post-voiding residual volume (PVRV). In addition, the relevant patient symptoms were evaluated using the International Prostate Symptom Score (IPSS) system.
The patients in the SRT group showed a statistically significant increment of the average MFR and AFR values and reduction of PV relative to the control group (p<0.05). The significant differences between the proportion of patients with prostate volume >40 ml in the SRE treated group vs. control group was observed (p<0.05). The mean IPSS score was highly significantly reduced in the SRT group (p<0.01).
The mild improvements of the urine flow, prostate size and IPSS score during 12 months treatment with the Serenoa repens extract indicate possible efficiency of this phytotherapeutic agent in patients with BPH.
Consideration of the Therapeutic Potential of Irrigants in Endodontic Therapy
Authors: Nogo-Zivanovic Dajana , Bjelovic Ljiljana , Ivanovic Vladimir , Kanjevac Tatjana , Tanaskovic Irena 
Published: October 2017

Abstract
The main objective of endodontic treatment is to remove vital and necrotic remnants of pulp tissue and microorganisms and their toxic products from the root canal. During chemo-mechanical endodontic preparation, a smear layer is formed on the wall of the canals. Due to an inability to remove all tissue remnants and the smear layer from the root canal by mechanical instrumentation, it is necessary to use irrigation to ensure sufficient cleaning and disinfection of the largest part of the root canalicular system. The most commonly used irrigants are sodium hypochlorite (Na-OCl), ethylenediaminetetraacetic acid (EDTA), citric acid and chlorhexidine (CHX). Recently, the irrigants QMix and MTAD have been introduced to the market. They are a mixture of different components having antimicrobial, organolytic and mineralytic effects on canal detritus and the smear layer. This review article investigates irrigants in terms of the nature of their effect, their efficiency, optimal concentration, and method of use, and the interactions between the irrigants most commonly used in endodontic therapy are discussed, with special emphasis on QMix and MTAD.
Динамічні здібності чи динамічні здатності?
Authors: Bogodistov Yevgen 
Published: October 2017

Ціль дослідження – проаналізувати концепції динамічних здібностей для формування коректної термінології.
Дизайн/Метод/Підхід дослідження. Дана теоретична статя базується на лінгвістичному аналізі ключових наукових робіт з динамічних здібностей.
Результати. Проаналізовано історичний розвиток динамічних здібностей із моменту запровадження терміну й до сьогодення. У роботі описано головні проблеми концепції, що можуть впливати на її розуміння і, як наслідок, коректний переклад. Розглянуто новітні розвитки теорії і дві пов’язані із цим наукові дискусії. Проаналізовано визначення організаційних здібностей та їх вплив на розуміння динамічних здібностей організації. Наведено основні визначення динамічних здібностей, що відображають різні аспекти наукової дискусії, що точиться навколо концепції.
Теоретичне значення дослідження. Дане дослідження важливе для розвитку концепції динамічних здібностей в українському науковому сегменті, оскільки в роботі запропоновано підхід для однозначного розуміння термінології цієї концепції.
Оригінальність/Цінність/Наукова новизна дослідження. У зв’язку із тим, що залежно від розуміння концепції, переклад термінології українською мовою може бути різним, запропоновано термінологію, яка найбільш точно відповідає сучасному її розумінню.
Тип статті – теоретична.
Dynamic managerial capabilities: lessons from non-profits in highly dynamic environments
Authors: Botts Moritz Martin 
Published: October 2017

Purpose. Drawing on the concept of dynamic managerial capabilities, to propose a model that incorporates managerial human and social capital, and managerial cognition in the dynamic capabilities framework.
Design/Method/Approach. The study is an empirical in the context of the current conflict in the eastern Ukraine and is an analysis a non-profit field with an extremely high dynamic environment. The data was collected using a quantitative survey with 70 private corps, non-commissioned officers, and higher-ranked officers.
Findings. The model provides a direct relationship between dynamic capabilities and dynamic managerial capabilities, whereby the latter is constituted by the perceived manager’s competence (manager’s human capital), manager’s team (manager’s social capital), and manager’s goal congruence towards the goals of the organization (managerial cognition).
Theoretical implications. This paper expanded the body of research on dynamic managerial capabilities by developing the following arguments: (1) dynamic managerial capabilities directly influence organizational dynamic capabilities; (2) managerial social capital mediates relationships between managerial human capital and organizational dynamic capabilities; (3) managerial social capital mediates relationships between managerial cognition and organizational dynamic capabilities.
Originality/value. This research not only shows how a non-profit organization can act efficiently, it is also an example of an application of strategic management theory to a practical field with life or death consequences.
Research limitations/Future research. This research opens avenues for future research on dynamic capabilities in non-profit organizations.
Paper type – empirical.
Apropiacionismos y resignificaciones de la obra “Various small fires” de Ed Ruscha. / Appropriationism and reinterpretations of the artwork “Various small fires” of Ed Ruscha
Authors: Mínguez García Hortensia 
Published: October 2017

Durante más de cincuenta años, los libros de artista de Ed Ruscha han favorecido una particular tendencia apropiacionista. Por ejemplo, su obra “Various Small Fires” (1964) ha sido “reescrita” por autores como Bruce Nauman (1969), Jonathan Monk (1969), Lucas Batten y Jonathan Sadler (2003), Thomas Galler (2009), Scott McCarney (2010), Doro Boehme y Eric Baskauskas (2010) y Marcella Hackbard (2010), generándose con ello, un movimiento de apropiacionionismos y resignificaciones que se cierra, al menos temporalmente, con “Various Small Shipwreck… and big Fires” (2016) de autoría propia.El objetivo del presente texto, es el de analizar dichas obras y sus relación con “Various Small Fires”, tomando a Ed Ruscha como fundador de discursividad, y al libro en sí, como icono para la memoria colectiva de los amantes de este género artístico y para la historia del hombre en general. Un análisis que nos ayudará a visualizar cómo algunos artistas bajo la figura del replicante han rehecho el estilo ruschiano para la construcción de nuevos discursos que, inevitablemente refractan, nuestras actuales prácticas de creación y producción editorial en un mundo cada vez más globalizado y dominado por los medios de comunicación masiva. Appropriationism and reinterpretations of the artwork “Various small fires” of Ed RuschaFor over fifty years, the artist’s books of Ed Ruscha have generated an appropriationist trend around the world. For example, his work “Various Small Fires” (1964) has been “rewritten” by authors such as: Bruce Nauman (1969), Jonathan Monk (1969), Luke Batten and Jonathan Sadler (2003), Thomas Galler (2009), Scott McCartney (2010), Doro Boehme and Eric Baskauskas (2010) and Marcella Hackbard (2010), etc. All of them have generated an appropriationist movement and resignifications which is closed, at least temporarily, with “Various Small Shipwreck ... and big Fires” ( 2016) of own authorship. The objetive of this text is to analyze these works and their relation to “Various Small Fires”, taking Ed Ruscha as founder of discourses, and the book itself, as an icon for the collective memory of lovers of this artistic genre and our history, too. Aso, this analysis will help us visualize how some artists under the figure of replicant have remade the style of Ruscha for the construction of new discourses that, inevitably, refracted our current practices of creating and publishing in an increasingly globalized world dominated by mass media.
La edición incómoda. Del ensamblaje como estrategia artística en las publicaciones periódicas / Uncomfortable editing. Assembly as an artistic strategy in periodicals.
Authors: Méndez Llopis Carles 
Published: October 2017

El presente texto parte del principio collage como iniciador de una revuelta representacional e institucional en el arte de la que el assemblage forma parte. Con ello se pretende profundizar en la teorización de las revistas ensambladas como medio de expresión, donde la experimentación artística por medio de la edición se formaliza a través del ensamblaje como estrategia que le otorga sentido. De este modo, llegar a vislumbrar no sólo la determinación del ensamblar como lógica y modus operandi idóneo para la concreción de estas publicaciones periódicas, sino también para la cimentación de sus tácticas de democratización artística en su crear colaborativo.Uncomfortable editing. Assembly as an artistic strategy in periodicals.The current letter starts at the collage principle as an initiator of a representational and institutional revolt in art, in which assemblage is involved. As a result, the text attempts to deepen in theorizing the assembling magazines as a medium of expression in which the artistic experimentation, by means of editing, formalizes through the assembly as a strategy that gives it meaning. Thus, the scope is to discern not only the determination of the assembly as a logical and appropriate modus operandi for the realization of these periodicals, but also for the foundation of their tactics of artistic democratization in their collaborative development.
Fatores facilitadores na implantação das estratégias de segurança dopaciente: estudo descritivo-exploratório
Authors: Oliveira João Lucas Campos de , Reis Gislene Aparecida Xavier dos , Souza Verusca Soares de , Costa Maria Antonia Ramos , Valera Ingrid Mayara Almeida , Matsuda Laura Misue 
Published: October 2017

Objetivo: investigar, na perspectiva de enfermeiros gestores, os meios/fatores que facilitam o processo de implantação de estratégias de segurança do paciente. Método: participaram 72 enfermeiros gestores de quatro hospitais universitários do estado do Paraná, por meio de entrevista individual, gravada e norteada pela questão “F ale-me sobre aspectos que facilitam a implantação das estratégias de segurança neste hospital”. Os depoimentos foram transcritos na íntegra, submetidos à análise de conteúdo na modalidade temática. Resultados: das falas emergiam duas categorias temáticas: “F erramentas da gestão como facilitadores na impl a n t a ç ã o d a s e s t r a t é g i a s d e s e g u r a n ç a d o p a c i e n t e ” e “ P r o c e s s o s e d u c a t i v o s : m e i o s que facilitam a implantação de estratégias de segurança do paciente”. C onclusão: constatou-se que o apoio da alta gerência contribuiu sobremaneira à implantação das estratégias de segurança, além da liderança militante por este bem e o aperfeiçoamento do capital humano — estritamente veiculado à característica de ensino das instituições.
Perfil das gestantes de alto risco hospitalizadas em uma maternidade: estudo descritivo
Authors: Azevedo Rosangela de Oliveira , Campos Ferreira Helen , Silvino Zenith Rosa , Pompeu Christovam Barbara 
Published: October 2017

Objetivo: descrever o perfil das gestantes de alto risco atendidas na maternidade do HUAP. Método: pesquisa documental, descritiva e retrospectiva, de abordagem quantitativa, realizada em um hospital de Niterói/RJ. Os dados foram coletados em 2013, por meio de 148 prontuários de gestantes de alto risco internadas no hospital, no período de 1º de julho de 2011 a 30 de junho de 2012; e tratados por estatística descritiva. Resultados: a maior parte das gestantes era jovem (até 30 anos), com companheiro e residiam na região Metropolitana II/RJ. Metade delas possuía de um a dois filhos vivos, 59,5% eram multigestas; 79,1% nunca abortaram; e 64,5% entre as que manifestaram parto anterior (n=93) foram submetidas à cesárea. Em relação à realização do pré-natal, 93,3% apresentaram registro de frequência às consultas. A maior parte das gestantes procurou o hospital por livre demanda (42,6%) por apresentarem sintomatologia de clínica geral. Foram identificadas 59 causas para a internação, com maior ocorrência em razão de amniorrexe prematura e de hipertensão arterial. Conclusão: os resultados apresentados podem desencadear propostas de protocolos de atendimento e acompanhamento dessa clientela.
Effect of intranasal ghrelin administration on the compulsive behavior patterns and the level of anxiety after the vital stress exposure to rats
Authors: Yakushina Natalia D. , Tissen Ilia Yu. , Lebedev Andrei A. , Pshenichnaya Anna G. , Bychkov Eugenii R. , Tsikunov Sergey G. , Shabanov Petr D. 
Published: October 2017

Aim. The effect of the intranasal ghrelin on the compulsive behavior and the anxiety in rats after exposure to vital stress was assessed in Wistar rats using a number of behavioral tests: marble test, elevated plus maze, open field and “resident intruder” test.
Methods. In the buring marble test, the behavioral components of the obsession (obsessive and obtrusive thoughts) and compulsions (obtrusive behavior), aimed to reduce anxiety, were modeled. Mental trauma was caused by a stressful effect, the essence of which was the experience of the animals of the circumstances of the death of a partner from the actions of a predator. A group of rats were placed once in the terrarium to a tiger python.
Results. After the action of vital mental stress in rats, two connected behavioral phenomena were observed: a high level of anxiety and an increase in the number of buried balls. This was accompanied by a decrease in communicability. Intranasal administration of ghrelin (10 µg in 20 µl for 7 days) after presentation of the vital stress reduced the level of anxiety, and also normalized the commpulsive behavior (the number of buried balls).
Conclusion. Thus, brain ghrelin is an important component of psychotraumatic mechanism. Ghrelin can potentially be considered as correctors of obsessive-compulsive disorders on the background of PTSD. Use of intranasal administration of ghrelin the clinic will allow the use of small doses of substances and thereby reduce their possible toxic effects.
Effect of astressin, a corticoliberin antagonist, on aggression and anxiety-fobic states in male rats reared in social isolation
Authors: Lebedev Andrei A. , Pshenichnaya Anna G. , Yakushina Natalia D. , Bychkov Eugenii R. , Shabanov Petr D. 
Published: October 2017

Aim. Intraspecific behavior, emotional and explorative activity were investigated after intranasal administration of astressin, a non-selective antagonist of CRF receptors, in the male rats reared in social isolation from 21 to 93 days.
Results. In the “resident-intruder” test there was an increased level of aggression and communications in isolated rats compared to grouped animals. After intranasal administration of astressin (20 μg in 20 μl), rats grown in isolation demonstrated an increase in aggression and decreased in communicability compared to intact animals reared in isolation. In the “open field” test a level of motor activity was increased in rats grown in isolation compared to grouped animals. The anxiety-phobic state, as well as behavior in an elevated plus maze, revealed enhance of anxiety and fear in rats reared in isolation. After astressin administration to isolated animals the levels of anxiety and fear significantly decreased.
Conclusion. The results of the work revealed that the antagonist of the CRF receptor astressin disinhibited aggression, removing anxious and phobic state in male rats reared in social isolation. The results prove the necessity of taking into account CRF mechanisms in the formation of the social isolation syndrome and the possibility of using CRF receptor antagonists to control the central mechanisms of stress and dependence in ontogenesis.
Effect of novelty stress on behavioral responses of Danio rerio and assessment of dose-dependent effects of anxiolytics of benzodiazepine structure with phenazepam as an example
Authors: Shabanov Petr D. , Lebedev Viktor A. , Lebedev Andrei A. , Bychkov Eugenii R. 
Published: October 2017

The effect of benzodiazepine anxiolytic phenazepam in Danio rerio was investigated. Previously, Danio rerio showed the effects of other anxiolytics, dia_zepam and chlordiazepoxide. The analysis of the anxiolytic effect of phenazepam in Danio rerio was carried out for the first time.
Methods. A stress test on novelty situation was used: a fish was placed first in a beaker with a dissolved pharmacological substance (or water) and then into a novel tank for 6 min, where the trajectory, the path length, the number of movements to the upper part of the novel tank, the number and time of the pattern of “freezing” for each min of the experiment were measured.
Results. In response to the novelty of tank, the fish was shown to react by submerging to the bottom, increasing the freezing, and reducing the number of movements to the upper half of the novel tank. After phenazepam exposure (administration), the fish was not only in the lower, but also in the upper part of the novel tank. The average path length did not change significantly in the range of the doses used. The number and time of the freezing, as well as the time spent in the lower part of the novel tank, 2-fold decreased compared to the control group of animals and showed a dose-dependent effect. The number of movements to the upper part of the novel tank for the experiment increased significantly from 1 in the control to 57 after phenazepam in a dose of 1 mg/l. When analyzing the dynamics of the parameters for each min, it was shown that the time of the fish in the lower part of the novel tank decreased from 3th min of the experiment with the use of phenazepam in a dose of 0.5 mg/l. At the same time, the number of movements of fish to the upper part of the novel tank significantly increased more than 2 times from 3th min of the experiment with the use of phenazepam in a dose of 1 mg/l.
Conclusion. The described method to study behavioral responses of Danio rerio on novelty stress is high sensitive in comparison with traditional behavioral methods of studing tranquilizers. The prospect of using Danio rerio as animal model in behavioral pharmacology is significant and does not concede research on rodents.
Prevalencia de embarazo en adolescentes, Yopal-Casanare, Colombia 2013-2014
Authors: Hernández Ávila Alejandra , Barrera Rodríguez Edwin Jesús , Castañeda Porras Oneida 
Published: October 2017

Objetivo: establecer la prevalencia de embarazo en mujeres adolescentes desde los registros de nacidos vivos del municipio de Yopal entre 2013-2014.Materiales y métodos: estudio descriptivo transversal desde la base de datos del módulo de nacidos vivos del Registro Único de Afiliados del Departamento Nacional de Estadística (DANE), suministrado por la Secretaría de Salud de Yopal. Se incluyeron registros completos de toda gestante menor de 19 años. Se estudiaron sus características sociodemográficas, antecedentes de la gestación y características específicas del nacimiento. Análisis mediante estadística descriptiva.Resultados: el 21,9 % (1.286/5.848) de registros correspondieron a gestantes adolescentes entre 10-19 años, con edad promedio 17,4 ± 1,47 años; edad promedio del padre 23,9 ± 5,66 años; mediana de embarazos = 1 (rango = 1-4); más de cuatro controles prenatales 707 (55,0 %); primigestantes 1.033 (80,3 %); periodo intergenésico menor de dos años 54 (25,7 %); parto espontáneo 894 (69,5 %) y cesárea 392 (30,5 %); presentaron bajo peso al nacer 54 (4,2 %) neonatos.Conclusión: la prevalencia del embarazo en adolescentes en Yopal fue superior a la nacional, de 19,5 %; las gestantes adolescentes del área rural acceden menos a los controles prenatales. Estos datos conllevan revisar y fortalecer las estrategias municipales de prevención de este evento.
Las infecciones de transmisión sexual: un problema de salud pública que Colombia debe enfrentar
Authors: Gaitán-Duarte Hernando 
Published: October 2017

El actual número de la Revista Colombiana de Obstetricia y Ginecología presenta un reporte de políticas públicas que resume la Estrategia Global de la Organización Mundial de la Salud (OMS) contra las Infecciones de Transmisión Sexual (ITS) para los años 2016 – 2021 en cumplimiento de la Agenda 2030 para el Desarrollo Sostenible que acordaron los países pertenecientes a las Naciones Unidas (UN), con el fin de lograr las metas para poner fin a la pobreza, proteger el planeta y garantizar la prosperidad para todos (1). El documento se enfoca también en los pasos que deberá dar Colombia para poder cumplir con las metas de la estrategia.La estrategia, que sigue la aproximación de la OMS a los problemas de salud pública, enfoca la atención a tres infecciones de transmisión sexual: la infección gonocócica, por el virus del papiloma humano y la sífilis, infecciones que conllevan serias consecuencias sobre la salud de la y la calidad de vida de la población en especial en las personas más vulnerables en Colombia.El documento hace una serie de recomendaciones a los países para que los gobiernos nacionales definan las políticas que permitan orientar acciones sostenibles que en el tiempo faciliten la construcción de capacidades institucionales, interinstitucionales y de gobernanza que garanticen la aplicación de las intervenciones que han demostrado ser seguras, efectivas y económicamente viables para el manejo de estas infecciones, con el fin de lograr su impacto en la mayor cantidad de personas vulnerables dentro de un escenario de respeto a los derechos humanos equidad de género y equidad en salud(2). Las acciones que incluye la estrategia están enfocadas en: a) el fortalecimiento de la vigilancia, la vigilancia y la evaluación del programa y el progreso; b) la prevención de las ITS; c) el diagnóstico precoz; d) el adecuado manejo de la paciente y su (s) pareja (s) y e) los enfoques para llegar a las poblaciones más vulnerables.