bluuebunny/crossref_metadata_2025_split huggingface dataset:
Escalating Health Care Expenditures in Cancer Decedents’ Last Year of Life: A Decade of Evidence from a Retrospective Population-Based Cohort Study in Taiwan
Authors: Hung Yen-Ni , Liu Tsang-Wu , Wen Fur-Hsing , Chou Wen-Chi , Tang Siew Tzuh 
Published: February 2017

Abstract

Background
No population-based longitudinal studies on end-of-life (EOL) expenditures were found for cancer decedents.

Methods
This population-based, retrospective cohort study examined health care expenditures from 2001 to 2010 among 339,546 Taiwanese cancer decedents’ last year of life. Individual patient-level data were linked from administrative datasets. Health care expenditures were converted from Taiwan dollars to U.S. dollars by health-specific purchasing power parity conversions to account for different health-purchasing powers. Associations of patient, physician, hospital, and regional factors with EOL care expenditures were evaluated by multilevel linear regression model by generalized estimating equation method.

Results
Mean annual EOL care expenditures for Taiwanese cancer decedents increased from 2000 to 2010 from U.S. $49,591 to U.S. $68,773, respectively, with one third of spending occurring in the patients’ last month. Increased EOL care expenditures were associated with male gender, younger age, being married, diagnosed with hematological malignancies and cancers other than lung, gastric, and hepatic-pancreatic cancers, and dying within 7–24 months of diagnosis. Patients spent less at EOL when they had higher comorbidities and metastatic disease, died within 6 months of diagnosis, were under care of oncologists, gastroenterologists, and intensivists, and received care at a teaching hospital with more terminally ill cancer patients. Higher EOL care expenditures were associated with greater EOL care intensity at the primary hospital and regional levels.

Conclusion
Taiwanese cancer decedents consumed considerable National Health Insurance disbursements at EOL, totaling more than was consumed in six developed non-U.S. countries surveyed in 2010. To slow increasing cost and improve EOL cancer care quality, interventions to ensure appropriate EOL care provision should target hospitals and clinicians less experienced in providing EOL care and those who tend to provide aggressive EOL care to high-risk patients.
<i>Polisse</i> e a dimensão (in)dizível da violência contra crianças e adolescente
Authors: Roure Glacy Queirós de 
Published: February 2017

Resumo: A teoria psicanalítica referenda a proposta deste artigo de discutir
sobre o filme francês Polissia (2011), de Maïwenn Le Besco. A análise
incide sobre um cinema cuja estética obstaculiza a presença de representações
idealizantes sobre a infância. Reflete sobre o modo como crianças
e adolescentes tem sido violentados no mundo adulto problematizando a
existência de uma espécie de silenciamento a que esses sujeitos são submetidos
em situações de proteção e acolhimento. Interpretada e enquadrada,
a partir de uma discursividade centrada nas categorias agressor e vítima, o
comum desconsiderar na fala da criança a condição de enigma que reveste
toda e qualquer narrativa que envolva situações de abuso e violência.

Palavras-chave: Crianças e adolescentes, Abuso e violência, Infância.
Sektor kultury jako czynnik transformacji miasta przemysłowego w kierunku miasta kreatywnego i inteligentnego? Przykład Łodzi
Authors: Sokołowicz Mariusz , Zasina Jakub 
Published: February 2017

Celem artykułu jest identyfikacja wpływu kultury w mieście na jego rozwój społeczno-gospodarczy w nawiązaniu do coraz bardziej powszechnego trendu polegającego na transformacji gospodarek miejskich w kierunku gospodarek „kreatywnych”. Prezentowane studium przypadku dotyczy Łodzi. W tym celu zbadano percepcję miejskiej oferty kulturalnej wśród mieszkańców. Jako metodę badawczą wykorzystano dynamiczną analizę ewolucji miasta jako systemu społeczno-gospodarczego (podejście systemowe ewolucyjne) wspartą techniką wywiadu kwestionariuszowego. Przeprowadzone badanie wskazuje, że pomimo wielu problemów ekonomicznych, z którymi boryka się to postindustrialne miasto, jest ono zdolne do dostosowania oferty kulturalnej do współczesnych potrzeb, wyeksponowania swojej specyfiki terytorialnej oraz wykorzystania kreatywności mieszkańców jako czynnika rozwoju społeczno-gospodarczego. Artykuł prezentuje ponadto zidentyfikowane problemy i wyzwania, na które musi odpowiedzieć miejska polityka kulturalna.
Znaczenie zimnych okresów późnego vistulianu w rozwoju rzeźby regionu łódzkiego
Authors: Dzieduszyńska Danuta 
Published: February 2017

Celem artykułu jest wykazanie znaczenia rzeźbotwórczej roli okresów cyklicznych powrotów zimna w późnym vistulianie w ewolucji regionu łódzkiego w świetle najnowszych interpretacji stratygraficznych i środowiskowych. Procesy rzeźbotwórcze późnego vistulianu były uruchamiane w środowiskach: stokowym, rzecznym i eolicznym działały w specyficznych warunkach niestabilności klimatycznej. Przejściowość tego okresu powodowała, że zazębiały się procesy charakterystyczne dla środowiska peryglacjalnego, przy udziale zmarzliny oraz dla środowiska umiarkowanego. Zimne fazy potencjalnie sprzyjały aktywności morfogenetycznej, chociaż ich świadectwa nie są w regionie łódzkim tak powszechne jak efekty procesów, które miały miejsce podczas wcześniejszych okresów vistuliańskich.
LEXIKÁLNE INTERFERENČNÉ PRVKY VO VOJVODINSKEJ SLOVENČINE
Authors: Makišova Ana 
Published: February 2017

Predmetom výskumu sú prejavy vojvodinských Slovákov (písané a hovorené). Slovenčina vo vojvodinskom prostredí sa dennodenne dostáva do kontaktu so srbčinou, čo značne vplýva na vyjadrovanie. Zvlášť je to výrazné u používateľov mladšej populácie, hlavne keď ide o súčasné trendy, nové pomenovania, ktoré sa preberajú zo srbčiny. Kontakt vojvodinskej slovenčiny so srbčinou je prirodzený a nevyhnutný. Vojvodinskí Slováci ovládajú oba jazykové systémy (slovenčinu a srbčinu) dostatočne pre každodenné používanie. Žijeme v bilingválnom prostredí, na dorozumievanie okrem slovenčiny používame aj srbčinu, ktorá ovplyvňuje naše vyjadrovanie. Pod vplyvom srbského jazyka použité lexémy často nadobúdajú inú podobu, nespisovnú a paralelne nastáva posun aj v sémantike (pridať – odovzdať; vypraviť – opraviť; Slováčka – Slovenka; nastaviť – pokračovať a pod).
PREDIKCIJA NAMERE ŽENA U SRBIJI DA TRAŽE PROFESIONALNU PSIHOLOŠKU POMOĆ
Authors: Šakotić-Kurbalija Jelena , Trifunović Biljana , Zotović Marija 
Published: February 2017

U cilju utvrđivanja u kojoj meri prisustvo stresnih životnih događaja, traženje psihološke podrške iz neformalnih socijalnih izvora i izbor strategija za suočavanje sa stresom, uz kontrolu uticaja različitih sociodemografskih varijabli, doprinose spremnosti žena u Srbiji da traže profesionalnu psihološku pomoć, prikupljeni su podaci na uzorku od 2206 žena, različitog socio-ekonomskog statusa, starosti od 19 do 76 godina. Namera žena da traže profesionalnu psihološku pomoć operacionalizovana je pitanjem o dosadašnjem iskustvu i planovima za traženje pomoći u budućnosti (Šakotić-Kurbalija, 2011); za procenu stresnih životnih događaja primenjena je modifikovana SLE skala (Survey of Life Events, Bradbury, 1990; modifikacija: Šakotić-Kurbalija, 2011). Brief COPE skalom (Carver, 1997) su ispitane strategije suočavanja sa stresom; dok su od sociodemografskih varijabli prikupljeni podaci o starosti ispitanice, radnom statusu, subjektivnoj proceni visine mesečnih prihoda domaćinstva, stepenu obrazovanja, redosledu rođenja, broju dece i broju članova domaćinstva. Rezultati hijerarhijske višestruke regresione analize pokazuju da je skup analiziranih prediktorskih varijabli statistički značajno povezan sa namerom da se traži profesionalna psihološka pomoć, ali je količina objašnjene varijanse relativno niska. Kao značajni prediktori namere traženja profesionalne psihološke pomoći izdvojeni su: ukupan broj negativnih stresnih događaja koji su se desili u proteklih godinu dana, sklonost ka korišćenju psihoaktivnih supstanci i traženju instrumentalne podrške od drugih, stepen obrazovanja, nekorišćenje poricanja u stresnim situacijama i religioznost. U manjoj meri, ovoj nameri doprinose i nemogućnost oslanjanja na neformalne izvore psihološke podrške, količina pozitivnog stresa, mesečni prihodi domaćinstva i starost ispitanice.
Status Wanita dan Ketahanan Pangan Rumah Tangga Nelayan dan Petani Padi di Kabupaten Muko-Muko Provinsi Bengkulu
Authors: Sukiyono Ketut , Cahyadinata Indra , Sriyoto NFN 
Published: February 2017

Kajian ini menggunakan kerangka konseptual gender dalam menentukan ketahanan pangan. Dengan menggunakan tiga indikator, artikel ini mencoba menunjukkan pengaruh dari status wanita relatif terhadap pria dalam rumah tangga pada ketahanan pangan pada dua rumah tangga yang berbeda basis ekonominya. Penelitian ini dilakukan di Kabupaten Muko-muko Provinsi Bengkulu. Dua ratus sembilan belas responden yang terdiri dari 110 rumah tangga nelayan dan 109 rumah tangga petani padi dipilih dengan menggunakan sampling acak sederhana. Model regresi berganda akan digunakan untuk menentukan faktor-faktor yang berpengaruh terhadap ketahanan pangan rumah tangga. Diantara dua kelompok rumah tangga dan dengan menggunakan ragam pangan sebagai indikator ketahanan pangan rumah tangga, rumah tangga nelayan menunjukkan derajat ketahanan pangan relatif lebih baik dibandingkan rumah tangga petani padi. Hasil penelitian juga menunjukkan bahwa status wanita tidak menunjukkan pengaruh yang nyata terhadap ketahanan pangan rumah tangga meskipun semua memiliki tanda yang sesuai. Sementara itu, pendapatan rumah tangga dan basis ekonomi rumah tangga mempunyai pengaruh yang nyata terhadap ketahanan pangan rumah tangga.
Subgluteal sciatic nerve block in a patient with haemorrhagic shock
Authors: Petrisor Cristina , Muresan Marius , Sallum Yusef 
Published: February 2017

SummaryRegional anaesthesia is not recommended in patients with haemorrhagic shock. This case report aims to raise awareness amongst anaesthetists that regional anaesthesia should be considered in selected cases of moderate haemorrhagic shock. We describe the use of an isolated sciatic nerve block in a morbidly obese patient, with moderate haemorrhagic shock due to arterial bleeding in the popliteal region. A subgluteal approach under real‐time ultrasound guidance, together with the use of peripheral nerve stimulation, aided rapid placement and onset of the regional anaesthesia block.
IMPORTÂNCIA DO CONHECIMENTO EM DERMATOLOGIA PARA ATENDIMENTO À POPULAÇÃO RIBEIRINHA DO RIO AMAZONAS
Authors: De Araújo Rodrigo S , Amorim da Costa Elisa M 
Published: February 2017

O atendimento a populações ribeirinhas do Rio Amazonas requer um conhecimento amplo em dermatologia, possibilitando ao profissional de saúde mais facilidade no diagnóstico e tratamento das afecções que acometem essa população. Este artigo tem como objetivo demonstrar que este conhecimento é de suma importância para qualquer profissional de saúde que realize atendimento a esta população. Este estudo, um relato de experiência, apresenta dados de atendimentos realizados de 08 a 19 de julho de 2013, por um discente da Universidade Severino Sombra, representando a instituição na Operação AssHop (Assistência Hospitalar a populações ribeirinhas do Amazonas), e tem o objetivo de analisar os atendimentos na área de dermatologia. De um total de 176 atendimentos realizados pelo discente, sempre sob supervisão médica, 30 foram dermatológicos, o que corresponde a 17% do total. Destes atendimentos, 33,3% foram dermatofitoses, 16,6% corresponderam à pitiríase alba , 16,6% foram diagnósticos de pitiríase versicolor e 33,3% outras dermatopatias, como molusco contagioso, ceratose actínica e dermatite atópica. Os pacientes receberam o tratamento específico de acordo com o diagnóstico. Constata-se que o conhecimento prévio em dermatologia é fundamental para realizar o atendimento a populações ribeirinhas do Rio Amazonas, visto que há uma grande demanda de quadros clínicos pertencentes a essa área.
Innovative Opioid Peptides and Biased Agonism: Novel Avenues for More Effective and Safer Analgesics to Treat Chronic Pain
Authors: Bedini Andrea , Spampinato Santi 
Published: February 2017

Background:
Chronic pain states are clinically relevant and yet unsolved conditions
impacting on quality of life and representing an important social and economic burden;
these diseases are poorly treated with the currently available drugs, being urgent the need of
innovative analgesics.

In this frame, novel analogues of endomorphin-1 and dermorphin emerge as promising starting
points to develop innovative, more effective analgesics to treat neuropathic pain.

Methods:
An extensive and structured search of bibliographic databases for peer-reviewed
research literature was undertaken using focused review questions; all the retrieved papers
were published on prestigious international journals by the experts of the field and were
carefully analyzed to collect all the information and data necessary to the conceptual framework
of this review.

Results:
One hundred papers were included in this review; forty-one defined the up-to-date
findings on neuropathic pain etiopathogenesis and its currently available treatment options.
Thirty-five papers described all the advantages and drawbacks of using endomorphin-1 (23)
or dermorphin (12) in the frame of neuropathic pain and outlined the most relevant advances
in developing endomorphin-1 and dermorphin analogs useful as potential, innovative analgesics.

Twenty-four papers provided the latest insights into exploiting biased agonism at opioid receptor
as an innovative strategy to develop more effective and safer analgesics.

Conclusion:
This review reports that innovative opioid peptides will be of great help in better
understanding the multifaceted scenario of neuropathic pain treatment, providing very
interesting opportunities for the identification of novel and more effective opioid analgesics
to be employed as medications.
Antimicrobial activity of Micrococcus luteus Cartenoid pigment
Authors: Majeed Huda Z. 
Published: February 2017

Cartenoids are group of pigments ,with enormous types different structurally and functionally, have colors range from red to yellow found in a wide variety of plants, fungi, algae and bacteria. The animals took from food because they cannot made it, on contrary, the plants and microbes produce them due to subjection to environment. The aim of the study is to isolate and characterize the cartenoid pigment from Micrococcus luteus. The pigment extraction was done by acetone, then was characterized with Ultra Violet –Visible spectroscopy (UV–Vis) and Fourier Transform Infrared (FTIR) spectroscopy. Then, it was tested for antibacterial activity against five different bacterial isolates and antifungal activity tests against six different fungal isolates by well diffusion method. The results found that, the extracted pigment having antibacterial activity and antifungal activity and having the ability to absorb UVA rays within the range of 300-500 nm. There were no significant difference in antimicrobial effect of pigment , even when the extraction and isolation were done by two culture medium (Nutrient Broth and Luria Bertani Broth). There were considerable inhibition percentages of adhesion after subjection to Cartenoid pigment ranged between (5.71, 23.84) % for Klebsiella spp. and Pseudomonas aeruginosa respectively and all the 11 isolate changed from Biofilm producer to non-producer. The isolated compound can be used against different bacterial and fungal infections. So they had a great future in medicine, cosmetics and as a sun protecting agent.
EVALUASI PROGRAM SERTIFIKASI KOMPUTER PADA UNIVERSITAS TEKNOLOGI INDONESIA MENGGUNAKAN MODEL CSE-UCLA
Authors: Divayana Dewa Gede Hendra , Sugiharni Gusti Ayu Dessy 
Published: February 2017

Penelitian ini bertujuan untuk mengetahui efektivitas pelaksanaan program sertifikasi komputer pada Universitas Teknologi Indonesia. Penelitian ini tergolong penelitian evaluatif dengan menggunakan model CSE-UCLA yang terdiri dari komponen system assesment, program planning, program implementation, program improvement dan program certification. Subjek penelitian ini terdiri dari: kepala laboratorium, tim pengelola sertifikasi, dan mahasiswa. Metode pengumpulan data dilakukan dengan kuesioner, observasi, wawancara, dan dokumentasi. Teknik analisis data dalam penelitian ini adalah deskriptif kuantitatif untuk menganalisis persentase tingkat efektivitas tiap-tiap komponen dalam model CSE-UCLA dan deskriptif kualitatif untuk menganalisis kendala-kendala yang menyebabkan hasil evaluasi tidak sesuai dengan standar keberhasilannya. Hasil evaluasi program sertifikasi komputer pada Universitas Teknologi Indonesia menunjukkan bahwa rata-rata tingkat efektivitas pelaksanaan program pada komponen system assesment sebesar 84,73%, program planning sebesar 83,87%, program implementation sebesar 85,24%, program improvement sebesar 84,17%, dan program certification sebesar 84,75%. Dengan melihat rata-rata hasil evaluasi pelaksanaan program sertifikasi komputer pada Universitas Teknologi Indonesia secara keseluruhan yaitu sebesar 84,55% maka tingkat efektivitas pelaksanaan program tergolong kategori baik.
Mathematical Study of Temperature Distribution in Human Dermal Part during Physical Exercises
Authors: Gurung Dil Bahadur , Shrestha Dev Chandra 
Published: February 2017

The purpose of this paper is to model metabolic rate that governs the behavior exhibited by various exercises over the period. This model equation is used in one dimensional Pennes’ bio-heat equation to study the temperature distribution in dermal part of tissue layers due to various exercises. The appropriate Dirichlet and Neumann boundary conditions are used. The solution of the bio-heat equation is then obtained using FEM technique and the simulated results are presented graphically. Journal of the Institute of Engineering, 2016, 12(1): 63-76
Prophylactic nimodipine treatment and improvement in hearing outcome after vestibular schwannoma surgery: a combined analysis of a randomized, multicenter, Phase III trial and its pilot study
Authors: Scheller Christian , Wienke Andreas , Tatagiba Marcos , Gharabaghi Alireza , Ramina Kristofer F. , Ganslandt Oliver , Bischoff Barbara , Zenk Johannes , Engelhorn Tobias , Matthies Cordula , Westermaier Thomas , Antoniadis Gregor , Pedro Maria Teresa , Rohde Veit , von Eckardstein Kajetan , Kretschmer Thomas , Kornhuber Malte , Steighardt Jörg , Richter Michael , Barker Fred G. , Strauss Christian 
Published: February 2017

OBJECTIVEIn clinical routines, neuroprotective strategies in neurosurgical interventions are still missing. A pilot study (n = 30) and an analogously performed Phase III trial (n = 112) pointed to a beneficial effect of prophylactic nimodipine and hydroxyethyl starch (HES) in vestibular schwannoma (VS) surgery. Considering the small sample size, the data from both studies were pooled.METHODSThe patients in both investigator-initiated studies were assigned to 2 groups. The treatment group (n = 70) received parenteral nimodipine (1–2 mg/hour) and HES (hematocrit 30%–35%) from the day before surgery until the 7th postoperative day. The control group (n = 72) was not treated prophylactically. Facial and cochlear nerve functions were documented preoperatively, during the inpatient care, and 1 year after surgery.RESULTSPooled raw data were analyzed retrospectively. Intent-to-treat analysis revealed a significantly lower risk for hearing loss (Class D) 12 months after surgery in the treatment group compared with the control group (OR 0.46, 95% CI 0.22–0.97; p = 0.04). After exclusion of patients with preoperative Class D hearing, this effect was more pronounced (OR 0.38, 95% CI 0.17–0.83; p = 0.016). Logistic regression analysis adjusted for tumor size showed a 4 times lower risk for hearing loss in the treatment group compared with the control group (OR 0.25, 95% CI 0.09–0.63; p = 0.003). Facial nerve function was not significantly improved with treatment. Apart from dose-dependent hypotension (p < 0.001), the study medication was well tolerated.CONCLUSIONSProphylactic nimodipine is safe and may be recommended in VS surgery to preserve hearing. Prophylactic neuroprotective treatment in surgeries in which nerves are at risk seems to be a novel and promising concept.Clinical trial registration no.: DRKS 00000328 (https://drks-neu.uniklinik-freiburg.de/drks_web/)
Electron Heating at Kinetic Scales in Magnetosheath Turbulence
Authors: Chasapis Alexandros , Matthaeus W. H. , Parashar T. N. , LeContel O. , Retinò A. , Breuillard H. , Khotyaintsev Y. , Vaivads A. , Lavraud B. , Eriksson E. , Moore T. E. , Burch J. L. , Torbert R. B. , Lindqvist P.-A. , Ergun R. E. , Marklund G. , Goodrich K. A. , Wilder F. D. , Chutter M. , Needell J. , Rau D. , Dors I. , Russell C. T. , Le G. , Magnes W. , Strangeway R. J. , Bromund K. R. , Leinweber H. K. , Plaschke F. , Fischer D. , Anderson B. J. , Pollock C. J. , Giles B. L. , Paterson W. R. , Dorelli J. , Gershman D. J. , Avanov L. , Saito Y. 
Published: February 2017

Abstract
We present a statistical study of coherent structures at kinetic scales, using data from the Magnetospheric Multiscale mission in the Earth’s magnetosheath. We implemented the multi-spacecraft partial variance of increments (PVI) technique to detect these structures, which are associated with intermittency at kinetic scales. We examine the properties of the electron heating occurring within such structures. We find that, statistically, structures with a high PVI index are regions of significant electron heating. We also focus on one such structure, a current sheet, which shows some signatures consistent with magnetic reconnection. Strong parallel electron heating coincides with whistler emissions at the edges of the current sheet.
Rotating Magnetic Structures Associated with a Quasi-circular Ribbon Flare
Authors: Li Haidong , Jiang Yunchun , Yang Jiayan , Yang Bo , Xu Zhe , Hong Junchao , Bi Yi 
Published: February 2017

Abstract
We present the detection of a small eruption and the associated quasi-circular ribbon flare during the emergence of a bipole occurring on 2015 February 3. Under a fan dome, a sigmoid was rooted in a single magnetic bipole, which was encircled by negative polarity. The nonlinear force-free field extrapolation shows the presence of twisted field lines, which can represent a sigmoid structure. The rotation of the magnetic bipole may cause the twisting of magnetic field lines. An initial brightening appeared at one of the footpoints of the sigmoid, where the positive polarity slides toward a nearby negative polarity field region. The sigmoid displayed an ascending motion and then interacted intensively with the spine-like field. This type of null point reconnection in corona led to a violent blowout jet, and a quasi-circular flare ribbon was also produced. The magnetic emergence and rotational motion are the main contributors to the energy buildup for the flare, while the cancellation and collision might act as a trigger.