bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupational exposure in MR facilities due to movements in the static magnetic field
Authors: Andreuccetti Daniele , Biagi Laura , Burriesci Giancarlo , Cannatà Vittorio , Contessa Gian Marco , Falsaperla Rosaria , Genovese Elisabetta , Lodato Rossella , Lopresto Vanni , Merla Caterina , Napolitano Antonio , Pinto Rosanna , Tiberi Gianluigi , Tosetti Michela , Zoppetti Nicola 
Published: August 2017

PurposeThe exposure of operators moving in the static field of magnetic resonance (MR) facilities was assessed through measurements of the magnetic flux density, which is experienced as variable in time because of the movement. Collected data were processed to allow the comparison with most recent and authoritative safety standards.MethodsMeasurements of the experienced magnetic flux density B were performed using a probe worn by volunteers moving in MR environments. A total of 55 datasets were acquired nearby a 1.5 T, 3 T, and 7 T whole body scanners. Three different metrics were applied: the maximum intensity of B, to be compared with 2013/35/EU Directive exposure limit values for static fields; the maximum variation of the vector B on every 3s‐interval, for comparison with the ICNIRP‐2014 basic restriction aimed at preventing vertigo effects; two weighted‐peak indices (for “sensory” and “health” effects: SENS‐WP, HLTH‐WP), assessing compliance with ICNIRP‐2014 and EU Directive recommendations intended to prevent stimulation effects.ResultsPeak values of |B| were greater than 2 T in nine of the 55 datasets. All the datasets at 1.5 T and 3 T were compliant with the limit for vertigo effects, whereas six datasets at 7 T turned out to be noncompliant. At 7 T, all 36 datasets were noncompliant for the SENS‐WP index and 26 datasets even for the HLTH‐WP one.ConclusionsResults demonstrate that compliance with EU Directive limits for static fields does not guarantee compliance with ICNIRP‐2014 reference levels and clearly show that movements in the static field could be the key component of the occupational exposure to EMF in MR facilities.
Temporally resolved parametric assessment of Z‐magnetization recovery (TOPAZ): Dynamic myocardial T1 mapping using a cine steady‐state look‐locker approach
Authors: Weingärtner Sebastian , Shenoy Chetan , Rieger Benedikt , Schad Lothar R. , Schulz‐Menger Jeanette , Akçakaya Mehmet 
Published: August 2017

PurposeTo develop and evaluate a cardiac phase‐resolved myocardial T1 mapping sequence.MethodsThe proposed method for temporally resolved parametric assessment of Z‐magnetization recovery (TOPAZ) is based on contiguous fast low‐angle shot imaging readout after magnetization inversion from the pulsed steady state. Thereby, segmented k‐space data are acquired over multiple heartbeats, before reaching steady state. This results in sampling of the inversion‐recovery curve for each heart phase at multiple points separated by an R‐R interval. Joint T1 and
estimation is performed for reconstruction of cardiac phase‐resolved T1 and
maps. Sequence parameters are optimized using numerical simulations. Phantom and in vivo imaging are performed to compare the proposed sequence to a spin‐echo reference and saturation pulse prepared heart rate–independent inversion‐recovery (SAPPHIRE) T1 mapping sequence in terms of accuracy and precision.ResultsIn phantom, TOPAZ T1 values with integrated
correction are in good agreement with spin‐echo T1 values (normalized root mean square error = 4.2%) and consistent across the cardiac cycle (coefficient of variation = 1.4 ± 0.78%) and different heart rates (coefficient of variation = 1.2 ± 1.9%). In vivo imaging shows no significant difference in TOPAZ T1 times between the cardiac phases (analysis of variance: P = 0.14, coefficient of variation = 3.2 ± 0.8%), but underestimation compared with SAPPHIRE (T1 time ± precision: 1431 ± 56 ms versus 1569 ± 65 ms). In vivo precision is comparable to SAPPHIRE T1 mapping until middiastole (P > 0.07), but deteriorates in the later phases.ConclusionsThe proposed sequence allows cardiac phase‐resolved T1 mapping with integrated
assessment at a temporal resolution of 40 ms. Magn Reson Med 79:2087–2100, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
Tomoelastography of the native kidney: Regional variation and physiological effects on in vivo renal stiffness
Authors: Marticorena Garcia Stephan Rodrigo , Grossmann Markus , Lang Sophia Theresa , Tzschätzsch Heiko , Dittmann Florian , Hamm Bernd , Braun Jürgen , Guo Jing , Sack Ingolf 
Published: August 2017

PurposeTo measure normal renal stiffness in adults, taking into account regional variation, hydration, and urinary status.MethodsThirty‐six healthy volunteers were examined by tomoelastography based on MR elastography at four frequencies, from 40 to 70 Hz and multifrequency shear wave speed recovery. Regional wave speeds were derived for the medulla, cortex (inner cortex and outer cortex), and renal pelvis, and examined for age‐related effects. Subgroups were repeatedly examined for reproducibility, amount of prior water drinking, and urinary status. Variations in renal perfusion were simulated ex vivo using a porcine kidney subjected to venous water inflow at different pressures.ResultsShear wave speed (stiffness) of renal parenchyma was 2.46 ± 0.12 m/s (inner cortex: 2.91 ± 0.17 m/s; outer cortex: 2.52 ± 0.11 m/s; medulla: 2.15 ± 0.08 m/s) without side differences and a tendency toward softening with age (P = 0.028). Corresponding intraclass correlation for reproducibility coefficients were 0.78 (inner cortex: 0.80; outer cortex: 0.81; medulla: 0.80). Water drinking resulted in slightly higher values in inner cortex and lower values in medulla (both P = 0.039), which was consistent with the results in perfused specimens. A full bladder led to higher renal pelvis stiffness (P = 0.004), whereas renal parenchyma remained uninfluenced. Stiffness of the porcine renal cortex increased with venous inflow pressure, whereas medulla stiffness decreased.ConclusionsTomoelastography provides full field of view maps of renal stiffness with highly detailed resolution and sensitivity to physiological effects related to age and fluid–solid tissue interactions. These basic data could be used to compare pathological conditions in the future. Magn Reson Med 79:2126–2134, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
A scalable detection and prevention scheme for voice over internet protocol (VoIP) signaling attacks using handler with Bloom filter
Authors: Ganesan Vennila , msk Manikandan 
Published: August 2017

SummaryIn this paper, a two‐tier model has been developed that includes a Handler and a Bloom filter (HBF). In the first‐tier, the handler detects both the flooding and fake signaling attacks. The Bloom filter, in the second‐tier, prevents both the attacks before reaching the victim. In the existing systems, the packet level features are used which do not perform well for detection and prevention of both the attacks. In this work, flow level features are applied in both tiers. The proposed model is implemented on the innocent Session Initiation Protocol (SIP) server in the VoIP network. The two‐tier model ensures the reliability and trustworthiness between the service provider and the customer. Besides, it also provides billing information along with the exact call duration to a customer who makes a call. The experimental results show that the HBF results in a reduced detection time of 9 seconds with the reduced false positive (FP) of less than 1% and the false negative (FN) of 0.002% and also preserves the voice call quality during media conversation.
NomadiKey: User authentication for smart devices based on nomadic keys
Authors: Souza Artur , Cunha Ítalo , B Oliveira Leonardo 
Published: August 2017

SummaryThe growing importance of smart devices calls for effective user authentication mechanisms. We argue that state‐of‐the‐art authentication mechanisms are either vulnerable to known attacks or do not meet usability needs. To address this problem, we designed NomadiKey, a user‐to‐device authentication mechanism based on nomadic keyboard keys. NomadiKey increases security level by placing keys at different screen coordinates each time it is activated. Besides, NomadiKey preserves usability by maintaining the traditional relative position of keys. To increase security even further, we also design an extension to NomadiKey that uses out‐of‐band channels to thwart shoulder‐surfing adversaries. We compare NomadiKey with other user authentication mechanisms under different attacks using statistical models and simulation. We also evaluate NomadiKey's usability with 20 users. Our results show that NomadiKey increases security compared to widely deployed PIN authentication with limited impact on authentication times.
Psychometric evaluation of a multi‐dimensional measure of satisfaction with behavioral interventions
Authors: Sidani Souraya , Epstein Dana R. , Fox Mary 
Published: August 2017

ABSTRACTTreatment satisfaction is recognized as an essential aspect in the evaluation of an intervention's effectiveness, but there is no measure that provides for its comprehensive assessment with regard to behavioral interventions. Informed by a conceptualization generated from a literature review, we developed a measure that covers several domains of satisfaction with behavioral interventions. In this paper, we briefly review its conceptualization and describe the Multi‐Dimensional Treatment Satisfaction Measure (MDTSM) subscales. Satisfaction refers to the appraisal of the treatment's process and outcome attributes. The MDTSM has 11 subscales assessing treatment process and outcome attributes: treatment components’ suitability and utility, attitude toward treatment, desire for continued treatment use, therapist competence and interpersonal style, format and dose, perceived benefits of the health problem and everyday functioning, discomfort, and attribution of outcomes to treatment. The MDTSM was completed by persons (N = 213) in the intervention group in a large trial of a multi‐component behavioral intervention for insomnia within 1 week following treatment completion. The MDTSM's subscales demonstrated internal consistency reliability (α: .65 − .93) and validity (correlated with self‐reported adherence and perceived insomnia severity at post‐test). The MDTSM subscales can be used to assess satisfaction with behavioral interventions and point to aspects of treatments that are viewed favorably or unfavorably.
How Short Is Short, and Why? A Probable Case of Proportionate Dwarfism From Egypt's Third Intermediate Period in the Dakhleh Oasis, Egypt
Authors: Molto J. E. , Kirkpatrick C. L. 
Published: August 2017

AbstractThis study describes a probable proportionate dwarf from a Third Intermediate Period cemetery at Ain Tirghi in the Dakhleh Oasis, Egypt. The skeleton (Burial 22 or B22) is an adult woman estimated to be in her mid‐to‐late thirties. Most medical literature defines an adult stature of 2 standard deviations below the population mean as an indicator for clinically short stature, with some bioarchaeologists and clinicians identifying severe short stature at 3 standard deviations below the population mean. B22 satisfies either criteria when compared with the Ain Tirghi adult female population mean for measurements of the radii and femora, as well as the summed measurements of the femora and tibiae. Her limb proportions were normal, and this, with a lack of morphological abnormalities, eliminated several possible causes of small stature (e.g. achondroplasia). The differential diagnosis for an individual with short stature and normal proportions indicates that she represents a probable case of pituitary dwarfism or hypopituitarism. B22 was buried in the same fashion as adjacent burials in a family group burial and showed no differential indication of physiological stress or illness. Contextualised with the Egyptological and archaeological evidence of dwarfism in Egypt, this case study considers the social perceptions of dwarfism in ancient Egypt and suggests that pituitary dwarfs, like disproportionate dwarfs, likely led normal, if not privileged lives. Therefore, according to the social theory of disability, B22 was not necessarily disabled despite her impairment. Copyright © 2017 John Wiley & Sons, Ltd.
Early Pregnancy Weight Gain Exerts the Strongest Effect on Birth Weight, Posing a Critical Time to Prevent Childhood Obesity
Authors: Broskey Nicholas T. , Wang Peng , Li Nan , Leng Junhong , Li Weiqin , Wang Leishen , Gilmore L. Anne , Hu Gang , Redman Leanne M. 
Published: August 2017

ObjectiveGestational weight gain (GWG) is associated with infant birth weight and childhood obesity; however, the patterns of GWG on infant birth weight are poorly understood.MethodsThis analysis in 16,218 mother‐child dyads from Tianjin, China, determined the risk of infant size at birth according to GWG occurring throughout the first and second trimester (early GWG) or during the third trimester (late GWG), according to maternal prepregnancy BMI and the 2009 Institute of Medicine recommendations.ResultsExcessive GWG in early and late pregnancy had an increased risk for large‐for‐gestational‐age (LGA) infants (odds ratio [OR]: 2.4; 95% confidence interval [CI]: 1.5‐4.0, P < 0.001). Regardless of prepregnancy BMI, excessive GWG early in pregnancy (< 24 weeks) was associated with an increased risk of LGA infants (OR: 2.5; 95% CI: 2.1‐3.1, P < 0.001), and inadequate early GWG was associated with a higher risk of small‐for‐gestational‐age (SGA) infants (OR: 1.4; 95% CI: 1.2‐1.7, P < 0.001).ConclusionsThe pattern of GWG early in pregnancy, regardless of GWG later in pregnancy, had the greatest impact on infant size at birth. Interventions initiated early in pregnancy may facilitate better adherence to the GWG guidelines and minimize the risk of LGA and SGA infants, a potential precursor for childhood obesity.
Optimal control problem for some integrodifferential equations in Banach spaces
Authors: Diallo Mouhamadou Alpha , Ezzinbi Khalil , Sène Abdoulaye 
Published: August 2017

SummaryIn this work, we study the existence and stability of solutions for an optimal control problem governed by an integrodifferential equation with compact control set in the space L1([0,b];X). The stability results, in the sense of Baire category theory, for optimal control problems are obtained by the theory of set‐valued mapping and the notion of essential solutions for optimal control problems.
Propanolysis of arenesulfonyl chlorides: Nucleophilic substitution at sulfonyl sulfur
Authors: Iazykov Mykyta , Canle Moisés , Santaballa J. Arturo , Rublova Ludmila 
Published: August 2017

AbstractWe have studied the mechanism of solvolysis of arenesulfonyl chlorides by propan‐1‐ol and propan‐2‐ol at 303‐323 K. Kinetic profiles were appropriately fit by first‐order kinetics. Reactivity increases with electron‐donating substituents. Ortho‐alkyl substituted derivatives of arenesulfonyl chlorides show increased reactivity, but the origin of this “positive” ortho‐effect remains unclear. Likely, ortho‐methyl groups restrict rotation around the C‐S bond, facilitating the attack of the nucleophile. No relevant reactivity changes have been found with propan‐1‐ol and propan‐2‐ol in terms of nucleophile steric effect. The existence of isokinetic relationships for all substrates suggests a single mechanism for the series. Solvolysis reactions of all substrates in both alcohols show isokinetic temperatures (Tiso) close to the working temperature range, which is an evidence of the process being influenced by secondary reactivity factors, likely of steric nature in the TS. Solvation plays a relevant role in this reaction, modulating the reactivity. In some cases, the presence of t‐Bu instead of Me in para‐ position leads to changes in the first solvation shell, increasing the energy of the reaction (ca. 1 kJ·mol−1). The obtained results suggest the same kinetic mechanism of solvolysis of arenesulfonyl chlorides for propan‐1‐ol and propan‐2‐ol, as in MeOH and EtOH, where bimolecular nucleophilic substitution (SN2) takes place with nucleophilic solvent assistance of one alcohol molecule and the participation of the solvent network involving solvent molecules of the first solvation shell.
Effect of anionic surfactant on alginate‐chitosan polyelectrolyte multilayer thickness
Authors: Kaygusuz Hakan , Micciulla Samantha , Erim F. Bedia , von Klitzing Regine 
Published: August 2017

ABSTRACTAlginate and chitosan are among the most common biopolyelectrolytes. Surfactants can be included in alginate and chitosan formulations in order to improve their physical and functional properties. In the present study, the effect of the anionic surfactant sodium dodecyl sulfate (SDS) on alginate‐chitosan polyelectrolyte multilayer (PEM) films is reported for the first time. Layer‐by‐layer deposition technique was employed to prepare the PEM samples and the samples were characterized by ellipsometry, X‐ray reflectivity, atomic force microscopy, and quartz crystal microbalance with dissipation. Incorporation of SDS into PEM formulations increased the film thickness and an increased adsorption behavior between alginate and chitosan layers are observed. Since the concentration of SDS was below its critical micelle concentration, no micelle formation was expected and hydrophobic‐hydrophobic interaction between alginate and SDS might be the main reason. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2017, 55, 1798–1803
Patterns of stress coping and depression among patients with head and neck cancer: A Japanese cross‐sectional study
Authors: Ichikura Kanako , Yamashita Aya , Sugimoto Taro , Kishimoto Seiji , Matsushima Eisuke 
Published: August 2017

AbstractObjectivePatients with head and neck cancer (HNC) experience many stressful problems with breathing, eating, swallowing, and/or speaking. The aim of this study was to (a) identify the clusters of HNC patients based on their stress coping strategies and (b) evaluate the differences in clinical data and depression among the identified HNC patients' coping clusters.MethodsWe conducted a single‐center, cross‐sectional study with self‐completed questionnaires for patients with HNC between April and August 2013. We measured stress coping (an abbreviated version of the COPE Inventory: Brief COPE) and depression (the Japanese version of the Beck Depression Inventory‐II: BDI‐II).ResultsOf the 116 patients who completed all the questionnaires, 81 (69.8%) participants were 60 to 79 years old and 105 (90.5%) were men. Cluster analysis based on the standardized z score of Brief COPE showed that patients were classified into 3 clusters, labeled “dependent coping,” “problem‐focused coping,” and “resigned coping.” The ANOVA revealed that depression (BDI score) was significantly higher in the dependent‐coping cluster compared with the problem‐focused coping.ConclusionsThis study indicates that patients with a dependent‐coping pattern may account for the largest HNC population and are likely to suffer from depression. Dependent coping includes smoking, drinking, seeking support, or engaging self‐distraction. In the future, we should develop psychological intervention programs focused on coping strategies and enhancement of the support system for patients with HNC.
Factors influencing time to seeking medical advice and onset of treatment in women who are diagnosed with breast cancer in Serbia
Authors: Stamatovic L. , Vasovic S. , Trifunovic J. , Boskov N. , Gajic Z. , Parezanovic A. , Icevic M. , Cirkovic A. , Milic N. 
Published: August 2017

AbstractObjectiveStreamlining the diagnosis is a key factor in improving the treatment outcomes for breast cancer. The aim of this study was to determine factors influencing time to seeking medical advice and treatment onset in women who are diagnosed with breast cancer in Serbia.MethodsThe study was a multicenter, cross‐sectional national survey, performed at 10 oncology centers in Serbia. Time intervals spent throughout the complex diagnostic pathway were evaluated using a validated questionnaire administered to women with breast cancer (n = 800). Total interval (TI) was determined using predefined time scales, including one referring to patient interval (PI), and several related to health care system interval (SI).ResultsMean PI, SI, and TI were 4.5, 9.2, and 12.9 weeks, respectively; 20% of patients had a PI>12 weeks. Based on the multivariate regression model, longer PI was associated with perceived lack of time and personal disregard or trivialization of detected symptoms and signs. Women who were supported by family members or friends and had at least a secondary level education tended to have a shorter PI. Longer PI was correlated with a longer SI, while regular self‐examination, having been diagnosed by an oncologist, and living in a major city were associated with shorter SI.ConclusionsSeveral factors, related to psychological, demographic, behavioral, and health system characteristics, determined both the time to seeking medical advice and treatment onset for breast cancer. These findings support review and refining of national strategies and policies to promote early detection, diagnosis, and treatment of breast cancer.
Avoidance of androgen deprivation therapy in radiorecurrent prostate cancer as a clinically meaningful endpoint for salvage cryoablation
Authors: Ginsburg Kevin B. , Elshafei Ahmed , Yu Changhong , Jones J. Stephen , Cher Michael L. 
Published: August 2017

BackgroundTo investigate the ability of salvage cryoablation of the prostate (SCAP) to delay the need for androgen deprivation therapy (ADT) in local recurrence after radiation therapy to the prostate using the Cryo‐On‐Line Database (COLD) registry.MethodsThe COLD registry is comprised of a combination of retrospectively and prospectively collected data on patients undergoing primary and SCAP. Patients with local recurrence after radiation therapy were identified. Kaplan‐Meier analysis was used to calculate ADT‐free survival.ResultsWe identified 898 patients that have undergone SCAP in the COLD registry. Overall, the calculated 5‐year ADT‐free survival probability was 0.713. When stratified by D'Amico risk group, 264 high‐risk patients (71.9%), 234 intermediate‐risk (86.7%),and 228 low‐risk (87.7%) were free of ADT post‐SCAP. This correlates with a 5‐year ADT‐free survival of 60.7, 73.9, and 82.4%, respectively. Patients with post‐SCAP PSA nadir of <0.2 ng/mL had a 5 year ADT‐free survival of 87.1% compared to 48.7% with a PSA nadir ≥0.2 ng/mL. Pre‐operative ADT use or full versus partial gland SCAP did not have an effect on ADT use post‐operatively. In 118 (55.4%) of patients with post‐operative biochemical recurrence, ADT was not used.ConclusionFor patients with local recurrence after radiation, SCAP is an option that provides a high chance of avoiding or delaying ADT. The potential to delay ADT and its associated side effects should be a part of counseling sessions with the patient when discussing treatment options for locally recurrent prostate cancer after radiation. Avoidance of ADT is more clinically relevant than PSA elevation.