bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender diversity in top management teams and corporate reputation: Evidence from Spanish listed companies
Authors: Martín‐Zamora María‐Pilar , Borralho João Miguel Capela , Hernández‐Linares Remedios 
Published: October 2024

AbstractCompanies gain significant advantages from having a favorable corporate reputation (CR), so researchers have analyzed the factors that contribute to the formation and maintenance of this intangible asset. One of these variables could be gender diversity in management. This study drew on stakeholder, signaling, and critical mass theories to explore how women in firms' top management teams (TMTs) can influence these organizations' CR. A sample of data on Spanish listed companies were collected for the period of 2017–2022. The results reveal that a positive relationship exists between gender diversity in TMTs and CR and that this relationship is moderated by women on boards of directors and by board independence. The findings contribute to the literature by providing evidence of top management's influence on CR. This empirical research also expands the literature on gender diversity in organizations by demonstrating that the positive impact of gender diversity on CR extends beyond boards of directors.
Autoethnographical Research on the Experience of Identity Change as an Artist, Teacher and Teaching Artist
Authors: Jeong Ok‐Hee 
Published: October 2024

AbstractAn autoethnographic exploration of identity formation raises the question of how individuals inhabit, negotiate, accommodate and resist the social groups to which they belong, continually coming to terms with who and what they are. This paper discusses, through this researcher's autobiographical exploration, the ways in which pedagogical discourse and practice produce identities that are constructed within the broader sociocultural context of arts education. As an art educator who has been learning and teaching in the Korean sociocultural context since the 1970s, I have experienced the struggle between my identity as an artist and my identity as a teacher amidst the changes in educational ideology reflected in the Korean national curriculum, which is a set of pedagogical discourses and practices that are constructed within a particular sociocultural context. It can be said that my autobiographical narration has important implications for the practice of art education in connecting individuals and society in an ambiguous and complex future society by enhancing theoretical understanding of wider social phenomena. In this paper, the narrative interpretation of my changing identity as an artist, an art teacher and a teaching artist provides a timely insight into identity shifts in how the artwork we encounter and our perceptions of art are shaped and transformed by our own cultural experiences and recollections of our own personal experiences within the interconnectedness of art and education across time.
Interest rate liberalization and corporate innovation: Evidence from natural experiments in China
Authors: Yu Shuangli , Ke Yun , Quan Xiaofeng , Ding Wenhong 
Published: October 2024

AbstractWe examine whether and how interest rate liberalization affects corporate innovation in China. Using the removal of the interest rate ceiling and floor as exogenous shocks, and the numbers of granted patents to proxy for corporate innovation, we find that corporate innovation increases after interest rate liberalization. Our finding holds through several robustness tests. Furthermore, we show that state‐owned enterprises (SOEs) and non‐SOEs benefit from interest rate liberalization differently: Non‐SOEs benefit more from interest rate ceiling removal, whereas SOEs benefit more from interest rate floor removal. Cross‐sectional analyses also show that the effect is more pronounced when bank competition is higher and when firms rely more on external finance. Exploring potential channels through which interest rate liberalization spurs innovation, we find that although ceiling removal mitigates firms’ financial constraints, floor removal lowers corporate loan costs. Our study provides evidence of how financial reform benefits the real economy.
Risk of Late Implant Loss and Peri‐Implantitis Based on Dental Implant Surfaces and Abutment Types: A Nationwide Cohort Study in the Elderly
Authors: Lee Su Young , Daher René , Jung Jin‐Hyung , Han Kyungdo , Sailer Irena , Lee Jae‐Hyun 
Published: October 2024

ABSTRACTAimThis nationwide population‐based cohort study aimed to assess the incidence of implant complication treatments, including implant removal procedures and peri‐implantitis treatments, in relation to implant surfaces and abutment types.MethodsData from the National Health Insurance Service, covering approximately 50 million individuals, were used. Implants and abutments were categorized by codes, including surfaces such as resorbable blasting media, sandblasted large grit and acid‐etched (SA) and hydroxyapatite coating, along with abutment structures (one‐piece straight, two‐piece straight, angled). The incidence of implant complication treatments was analysed using Kaplan–Meier curves and Cox proportional hazards regression (α = 0.05).ResultsThe study included 2,354,706 implants. The SA group had the lowest hazard ratio for implant removal procedures (p < 0.0001). No significant differences were found in the risk of peri‐implantitis treatments between implant surfaces (p = 0.0587). The risk of implant complication treatments did not differ significantly by the abutment type (p = 0.9542). The incidence rate of implant complication treatments was < 3.9 per 1000 implant‐years across all groups.ConclusionsThe SA group showed a slightly lower risk of late implant loss, whereas no significant association was found for the abutment type groups. All implant and abutment type groups showed an incidence rate of < 3.9 per 1000 implant‐years for complication treatments.
Comparison of targeted web‐based advertising versus traditional methods for recruiting older adults into clinical trials
Authors: Baldyga Kathryn , Iloputaife Ike , Taffet George , LaGanke Nicole , Manor Brad , Lipsitz Lewis A. , Millar Courtney L. 
Published: October 2024

AbstractBackgroundRecruiting older adults into clinical trials can be particularly challenging. Our objective was to determine if targeted web‐based advertising is an effective recruitment strategy.MethodsWe compared the recruitment rates of traditional and targeted web‐based methods for three representative clinical trials involving older adults. All studies utilized traditional recruitment methods initially, but shifted toward primarily targeted web‐based advertising after experiencing slow recruitment rates.ResultsWe found that web‐based advertising reached more individuals compared to traditional methods. Compared to traditional methods, web‐based methods also had at least twice the rate of expressed interest, completion of telephone and in‐person screening, eligibility, and enrollment. Additionally, the proportion of individuals excluded after the telephone screening did not differ according to whether targeted web‐based advertising (STAMINA: 51%; Berries and Steps: 62%; ISTIM: 20%) or traditional methods (STAMINA: 48%; Berries and Steps: 69%; ISTIM: 23%) were used within each study. Those recruited using web‐based advertisements tended to be younger compared to traditional methods, but were similar in racial distribution and education.ConclusionTargeted web‐based advertisements may be more effective in recruiting older adults for clinical trials at a faster rate than traditional recruitment methods, but need further evaluation of compatible study designs, potential population bias, and cost‐effectiveness.
Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis
Authors: Chen Luyun , Ren Zheng , Clark Kelly A. , Lou Carolyn , Liu Fang , Cao Quy , Manning Abigail R. , Martin Melissa L. , Luskin Elaina , O'Donnell Carly M. , Azevedo Christina J. , Calabresi Peter A. , Freeman Leorah , Henry Roland G. , Longbrake Erin E. , Oh Jiwon , Papinutto Nico , Bilello Michel , Song Jae W. , Kaisey Marwa , Sicotte Nancy L. , Reich Daniel S. , Solomon Andrew J. , Ontaneda Daniel , Sati Pascal , Absinta Martina , Schindler Matthew K. , Shinohara Russell T. ,   the NAIMS Cooperative
Published: October 2024

AbstractBackground and PurposeParamagnetic rim lesions (PRLs) are an MRI biomarker of chronic inflammation in people with multiple sclerosis (MS). PRLs may aid in the diagnosis and prognosis of MS. However, manual identification of PRLs is time‐consuming and prone to poor interrater reliability. To address these challenges, the Automated Paramagnetic Rim Lesion (APRL) algorithm was developed to automate PRL detection. The primary objective of this study is to evaluate the accuracy of APRL for detecting PRLs in a multicenter setting.MethodsWe applied APRL to a multicenter dataset, which included 3‐Tesla MRI acquired in 92 participants (43 with MS, 14 with clinically isolated syndrome [CIS]/radiologically isolated syndrome [RIS], 35 without RIS/CIS/MS). Subsequently, we assessed APRL's performance by comparing its results with manual PRL assessments carried out by a team of trained raters.ResultsAmong the 92 participants, expert raters identified 5637 white matter lesions and 148 PRLs. The automated segmentation method successfully captured 115 (78%) of the manually identified PRLs. Within these 115 identified lesions, APRL differentiated between manually identified PRLs and non‐PRLs with an area under the curve (AUC) of .73 (95% confidence interval [CI]: [.68, .78]). At the subject level, the count of APRL‐identified PRLs predicted MS diagnosis with an AUC of .69 (95% CI: [.57, .81]).ConclusionOur study demonstrated APRL's capability to differentiate between PRLs and lesions without paramagnetic rims in a multicenter study. Automated identification of PRLs offers greater efficiency over manual identification and could facilitate large‐scale assessments of PRLs in clinical trials.
Discourses of solidarity and resistance in alternative linguistic spaces: Galician improvised poetry as linguistic collective action
Authors: O'Rourke Bernadette , Dayán‐Fernández Alejandro 
Published: October 2024

AbstractThis article focuses on alternative ways of understanding language in the context of minority language advocacy through an examination of the Galician tradition of singing‐in‐verse, known as regueifa. It proposes the notion of “linguistic collective action” to refer to the battery of resistance and solidarity strategies that lead to social transformation, implemented in grassroots movements linked to language struggles that not only go beyond the binary tropes of “pride” and “profit”, but also transcend traditional ideas of how language revitalization should be carried out. To tap into the dynamics of this social movement, we draw on a multi‐sited ethnography of the interconnected spaces in which urban‐based Galician speakers engage in collective action through the practice of regueifa. We examine how progressive values (e.g.: LGBTQ+ advocacy, feminism, and anti‐neoliberalism) are intertwined with the use of minoritized language reclamation, acting as a trigger for social transformation.
Mental State Attribution Mediates Exogenous Orienting of Attention Triggered by Gaze Cues, but not Other Social Cues
Authors: Eito Hirokazu , Wakabayashi Akio , Ichikawa Makoto 
Published: October 2024

AbstractWe examined the properties in orienting visual attention that are triggered by social cues (eye gaze or pointing finger) and nonsocial cues (an arrow). Particularly, we investigated whether the mental state of others would be modulated by any social cue. We presented an occluder between the cue and target to manipulate the mental state of an agent in cues (i.e., whether the agent is aware of the target). For Experiment 1, the reaction time (RT) to detect the target was prolonged when the target side was occluded only in the gaze‐cue condition, but not for the arrow or the pointing finger. For Experiment 2, the RT of a discrimination task, which demanded greater cognitive demand, was not prolonged for any cue type. These results suggest that the mental state attribution for the agency of the cue, which is affected by an occluder, is specific to the gaze cue, and suggest that it is under top‐down control that requires cognitive resources.
Two plant membrane‐shaping reticulon‐like proteins play contrasting complex roles in turnip mosaic virus infection
Authors: Wu Guanwei , Wang Liping , He Rongrong , Cui Xiaoyan , Chen Xin , Wang Aiming 
Published: October 2024

AbstractPositive‐sense RNA viruses remodel cellular cytoplasmic membranes as the membranous sources for the formation of viral replication organelles (VROs) for viral genome replication. In plants, they traffic through plasmodesmata (PD), plasma membrane‐lined pores enabling cytoplasmic connections between cells for intercellular movement and systemic infection. In this study, we employed turnip mosaic virus (TuMV), a plant RNA virus to investigate the involvement of RTNLB3 and RTNLB6, two ER (endoplasmic reticulum) membrane‐bending, PD‐located reticulon‐like (RTNL) non‐metazoan group B proteins (RTNLBs) in viral infection. We show that RTNLB3 interacts with TuMV 6K2 integral membrane protein and RTNLB6 binds to TuMV coat protein (CP). Knockdown of RTNLB3 promoted viral infection, whereas downregulation of RTNLB6 restricted viral infection, suggesting that these two RTNLs play contrasting roles in TuMV infection. We further demonstrate that RTNLB3 targets the α‐helix motif 42LRKSM46 of 6K2 to interrupt 6K2 self‐interactions and compromise 6K2‐induced VRO formation. Moreover, overexpression of AtRTNLB3 apparently promoted the selective degradation of the ER and ER‐associated protein calnexin, but not 6K2. Intriguingly, mutation of the α‐helix motif of 6K2 that is required for induction of VROs severely affected 6K2 stability and abolished TuMV infection. Thus, RTNLB3 attenuates TuMV replication, probably through the suppression of 6K2 function. We also show that RTNLB6 promotes viral intercellular movement but does not affect viral replication. Therefore, the proviral role of RTNLB6 is probably by enhancing viral cell‐to‐cell trafficking. Taken together, our data demonstrate that RTNL family proteins may play diverse complex, even opposite, roles in viral infection in plants.
A More Efficient and Safer Improved Percutaneous Pedicle Screw Insertion Technique—Trajectory Dynamic Adjustment Technique, Technical Note, and Clinical Efficacy
Authors: Li Hao , Ding Zhiguo , Wei Bin , Ma Zhihao , Xie Jing , Tian Yonghao , Wang Lianlei , Liu Xinyu , Yuan Suomao 
Published: October 2024

ABSTRACTObjectivePercutaneous pedicle screw fixation (PPSF) technique requires a very precise entry point of the Jamshidi needle, which leads to repeated adjustments, damaging the pedicle and increasing radiation exposure. This study was designed to propose an improved percutaneous pedicle screw fixation technique‐trajectory dynamic adjustment (TDA) technique, and evaluate its feasibility and assess the clinical outcomes.MethodA total of 445 patients with lumbar spondylolisthesis or lumbar spinal stenosis associated with instability from June 2017 to May 2022 were included in the retrospective study. They were randomly separated into two groups. Two hundred thirty‐one patients underwent TDA technique (TDA group). Two hundred fourteen patients underwent traditional PPSF technique (PPSF group). All patients underwent postoperative CT to assess the accuracy of screw placement, superior facet joint violation (FJV). The evaluated clinical outcomes were needle insertion time, radiation exposure, blood loss, hospital stay, the Japanese Orthopedic Association (JOA) score, the Visual Analogue Scale (VAS) scores for lower back pain (LBP), and leg pain, lumbar interbody fusion rate, and postoperative complications. The independent‐sample t test and paired t‐test were used for continuous data. The contingency table and Mann–Whitney U test were used for categorical data.ResultsThe time of the insertion in TDA group was significantly lower than that in PPSF group (p < 0.05). Similarly, the fluoroscopy frequency in TDA group was significantly lower than that in PPSF group (p < 0.05). There was no difference in intraoperative blood loss and hospital stay between the two groups (p > 0.05). Overall, there was no significant difference in the proportion of clinically acceptable screws between the two groups (p > 0.05). In addition, the lateral screw misplacement in TDA group was higher. Moreover, FJV rate was significantly lower than that in PPSF group (p < 0.05). In both TDA group and PPSF group, postoperative back and leg pain and the JOA score were significantly improved (p < 0.05). However, there were no significant differences in the pre‐ and postoperative VAS score for back and leg pain and the JOA score, JOA recovery rate, intervertebral fusion rate, and complications rate between the two groups (p > 0.05).ConclusionCompared to traditional PPSF technique, TDA technique is a safer and more effective procedure which has shorter surgical time, lower radiation exposure, and lower facet joint violation rate.
Amur Grape VaMYB4a‐VaERF054‐Like Module Regulates Cold Tolerance Through a Regulatory Feedback Loop
Authors: Lv Kai , Xie Yaping , Yu Qinhan , Zhang Ningbo , Zheng Qiaoling , Wu Jieping , Zhang Junxia , Li Junduo , Zhao Huixian , Xu Weirong 
Published: October 2024

ABSTRACTCold stress can limit the growth and development of grapevines, which can ultimately reduce productivity. However, the mechanisms by which grapevines respond to cold stress are not yet fully understood. Here, we characterized an APETALA2/ethylene response factor (AP2/ERF) which was shown to be a target gene of our previously identified VaMYB4a from Amur grape. We further investigated the molecular interactions between VaMYB4a and VaERF054‐like transcription factors in grapes and their role in cold stress tolerance. Our results demonstrated that VaMYB4a directly binds to and activates the VaERF054‐like gene promoter, leading to its enhanced expression. Moreover, we also explored the influence of ethylene precursors and inhibitors on VaERF054‐like expression and grape cold tolerance. Our findings indicate that VaERF054‐like contribute to cold tolerance in grapes through modulation of the ethylene pathway and the CBF signal pathway. Overexpression of VaERF054‐like in Vitis vinifera ‘Chardonnay’ calli and transgenic grape lines resulted in increased freezing stress tolerance, confirming its role in the cold stress response. We further confirmed the interaction between VaMYB4a and VaERF054‐like in vivo and in vitro. The co‐transformation of VaMYB4a and VaERF054‐like in grape calli demonstrates a synergistic interaction, enhancing the cold tolerance through a regulatory feedback mechanism. Our finding provides new insights into grape cold tolerance mechanisms, potentially contributing to the development of cold‐resistant grape varieties.
Psychiatric Comorbidities in Pediatric Trichotillomania: A Multicenter Cohort Study
Authors: Games Margaux , Sejdiu Zane , Ilyas Erum N. 
Published: October 2024

ABSTRACTBackgroundTrichotillomania (TTM) significantly increases the risk of psychiatric comorbidities. Sparse research in pediatric populations necessitates larger studies to assess these risks. This study investigates the risk of developing psychiatric comorbidities in pediatric TTM patients.MethodsThis case–control study assessed pediatric patients (< 18 years old) with TTM diagnosed between May 18, 2013, and January 1, 2024, using US‐based data from the TriNetX global research network. TTM patients (ICD‐10 diagnostic category F63.3) aged 18 years or younger at diagnosis and control patients (ICD‐10 code Z00.129) matched for age, sex, race, and ethnicity were assessed. Propensity score matching yielded 16,590 patients in each cohort. The analysis assessed subsequent diagnoses of ADHD, conduct disorders, tic disorders, obsessive‐compulsive disorder, anxiety disorders, dissociative, stress‐related, and somatoform disorders, mood disorders, and suicide attempts compared to controls.ResultsTTM patients under 18 years exhibited significantly greater risks of subsequent diagnoses for ADHD (OR: 2.002; CI 1.841–2.178; p < 0.001), conduct disorders (OR: 3.668; 3.2–3.668; p < 0.0001), tic disorders (OR: 2.247; 1.826–2.765; p < 0.0001), obsessive‐compulsive disorder (OR: 11.047; 8.822–13.832; p < 0.0001), anxiety disorders (OR: 3.583; 3.387–3.7; p < 0.0001), dissociative, stress‐related, and somatoform disorders (OR: 6.179; 3.935–9.701; p < 0.0001), mood disorders (OR: 2.476; 2.288–2.68; p < 0.0001), and suicide attempts (OR: 1.81; 1.121–2.924; p = 0.0139) compared to controls. TTM patients had the greatest risk of psychiatric diagnosis 1 year postindex event.ConclusionsPediatric TTM patients have higher psychiatric comorbidity risks, necessitating timely intervention and comprehensive management. Dermatologists can facilitate access to behavioral and pharmacological care, enhancing patient outcomes.
Longitudinal Changes in Estimated Glomerular Filtration Rate Following Repeat Heart Transplant in Children and Young Adults
Authors: Chan Melvin , Silveira Lori , Patterson Daniel J. , Bock Margret E. , Pietra Biagio A. , Everitt Melanie D. , Simpson Kathleen E. , Miyamoto Shelley D. , Auerbach Scott R. 
Published: October 2024

ABSTRACTBackgroundChronic kidney disease (CKD) is common after heart transplantation (HT). There are scarce studies looking at longitudinal changes in estimated glomerular filtration rate (eGFR) after repeat HT (RT) and risk factors for the presence of CKD3 post‐RT.MethodsFirst‐time HT recipients (FT) were matched with RT, based on age at transplant, sex, race, and transplant era. eGFR was derived from CKiD‐U25 formula using creatinine. Changes in eGFR were measured within and between patients using a mixed effects model. Logistic regression and survival analysis were performed to identify significant risk factors for CKD3 presence post‐RT.ResultsThe unmatched cohort included 393 HT recipients and 47 RT. 29 patients in both groups with at least 2 years of follow‐up data underwent matching. Over 6 years, the mean eGFR for FT and RT did not significantly change overtime. For those with CKD3 or higher prior to RT, 73% improved to CKD2 or lower at 2 years post‐RT. Risk factors for CKD3 post‐RT included female sex (OR 17.5 [1.7–181.9], p = 0.017) and greater than two acute kidney injuries (AKI) between FT and RT (OR 1.77 [1.06–2.95], p = 0.03). Approximately 50% of females and those with greater than two AKIs maintained or developed CKD3 at 7.5 and 3 years, respectively.ConclusionThis study provides data on longitudinal changes in eGFR over 6 years and finds that female sex and repeat HT recipients with greater 2 AKIs between transplants are at greatest risk for CKD3 presence post‐RT.
Pediatric Cardiac Xenotransplantation and Expanded Access: Ethical Considerations
Authors: Hurst Daniel J. , Bobier Christopher , Merlocco Anthony , Padilla Luz A. , Rodger Daniel , Cleveland David , Cleveland John D. 
Published: October 2024

ABSTRACTDue to the current organ shortage waitlist, alternatives to allotransplantation are necessary. Xenotransplantation is currently being pursued as one such alternative in adults in need of kidney or heart transplantation. Cardiac xenotransplantation of genetically modified pig hearts has been conducted twice in adults under the United States Food and Drug Administration (FDA) expanded access criteria. Because of the shortage of transplantable hearts for children as well as the lack of mechanical circulatory support in this population, pediatric researchers are exploring FDA expanded access in high‐risk neonates and infants who lack alternative options for survival. The adult cardiac xenotransplantation experience with expanded access can provide lessons and highlight nuances for researchers preparing pediatric application. This includes aspects of informed consent, biosurveillance, and protection of bystanders from potential xenozoonoses.