bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clustering of quasars in a wide luminosity range at redshift 4 with Subaru Hyper Suprime-Cam Wide-field imaging
Authors: He Wanqiu , Akiyama Masayuki , Bosch James , Enoki Motohiro , Harikane Yuichi , Ikeda Hiroyuki , Kashikawa Nobunari , Kawaguchi Toshihiro , Komiyama Yutaka , Lee Chien-Hsiu , Matsuoka Yoshiki , Miyazaki Satoshi , Nagao Tohru , Nagashima Masahiro , Niida Mana , Nishizawa Atsushi J , Oguri Masamune , Onoue Masafusa , Oogi Taira , Ouchi Masami , Schulze Andreas , Shirasaki Yuji , Silverman John D , Tanaka Manobu M , Tanaka Masayuki , Toba Yoshiki , Uchiyama Hisakazu , Yamashita Takuji 
Published: October 2017

Abstract
We examine the clustering of quasars over a wide luminosity range, by utilizing 901 quasars at $\overline{z}_{\rm phot}\sim 3.8$ with −24.73 &lt; M1450 &lt; −22.23 photometrically selected from the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) S16A Wide2 date release and 342 more luminous quasars at 3.4 &lt; zspec &lt; 4.6 with −28.0 &lt; M1450 &lt; −23.95 from the Sloan Digital Sky Survey that fall in the HSC survey fields. We measure the bias factors of two quasar samples by evaluating the cross-correlation functions (CCFs) between the quasar samples and 25790 bright z ∼ 4 Lyman break galaxies in M1450 &lt; −21.25 photometrically selected from the HSC dataset. Over an angular scale of 10${^{\prime\prime}_{.}}$0 to 1000${^{\prime\prime}_{.}}$0, the bias factors are $5.93^{+1.34}_{-1.43}$ and $2.73^{+2.44}_{-2.55}$ for the low- and high-luminosity quasars, respectively, indicating no significant luminosity dependence of quasar clustering at z ∼ 4. It is noted that the bias factor of the luminous quasars estimated by the CCF is smaller than that estimated by the auto-correlation function over a similar redshift range, especially on scales below 40${^{\prime\prime}_{.}}$0. Moreover, the bias factor of the less-luminous quasars implies the minimal mass of their host dark matter halos is 0.3–2 × 1012 h−1 M⊙, corresponding to a quasar duty cycle of 0.001–0.06.
Impact of global change on future Ebola emergence and epidemic potential in Africa
Authors: Redding D. W. , Atkinson P. M. , Cunningham A. A. , Lo Iacono G. , Moses L. M. , Wood J. , Jones K. E. 
Published: October 2017

ABSTRACTAnimal-borne or zoonotic human diseases (e.g., SARS, Rabies) represent major health and economic burdens throughout the world, disproportionately impacting poor communities. In 2013-2016, an outbreak of the Ebola virus disease (EVD), a zoonotic disease spread from animal reservoirs caused by the Zaire Ebola virus (EBOV), infected approximately 30,000 people, causing considerable negative social and economic impacts in an unexpected geographical location(Sierra Leone, Guinea, and Liberia). It is not known whether the spatial distribution of this outbreak and unprecedented severity was precipitated by environmental changes and, if so, which areas might be at risk in the future. To better address the major health and economic impacts of zoonotic diseases we develop a system-dynamics approach to capture the impact of future climate, land use and human population change on Ebola (EVD). We create future risk maps for affected areas and predict between a 1.75-3.2 fold increase in EVD outbreaks per year by 2070. While the best case future scenarios we test saw a reduction in the likelihood of epidemics, other future scenarios with high human population growth and low rates of socioeconomic development saw a fourfold increase in the risk of epidemics occurring and almost 50% increase in the risk of catastrophic epidemics. As well as helping to target where health infrastructure might be further developed or vaccines best deployed, our modelling framework can be used to target global interventions and forecast risk for many other zoonotic diseases.Significance StatementDespite the severe health and economic impacts of outbreaks of diseases like SARS or Zika, there has been surprisingly little progress in predicting where and when human infectious disease outbreaks will occur next. By modelling the impacts of future climate, land use and human population change on one particular disease Ebola, we develop future risk maps for the affected areas and predict 1.7-3.2 times as many human Ebola outbreaks per year by 2070, and a 50% increase in the chance that these outbreaks will become epidemics. As well as helping to target where health infrastructure might be further developed or vaccines deployed, our approach can also be used to target actions and predict risk hotspots for many other infectious diseases.
Distinct glycosaminoglycan chain length and sulfation patterns required for cellular uptake of Tau, Aβ, and α-Synuclein
Authors: Stopschinski Barbara E. , Holmes Brandon B. , Miller Gregory M. , Vaquer-Alicea Jaime , Hsieh-Wilson Linda C. , Diamond Marc I. 
Published: October 2017

AbstractTranscellular propagation of aggregate “seeds” has been proposed to mediate progression of neurodegenerative diseases in tauopathies and α-synucleinopathies. We have previously determined that tau and α-synuclein aggregates bind heparan sulfate proteoglycans (HSPGs) on the cell surface. This mediates uptake and intracellular seeding. The specificity and mode of binding to HSPGs has been unknown. We used modified heparins to determine the size and sulfation requirements of glycosaminoglycan (GAGs) binding to aggregates in biochemical and cell uptake and seeding assays. Aggregates of tau require a precise GAG architecture with defined sulfate moieties in the N- and 6-O-positions, whereas α-synuclein and Aβ rely slightly more on overall charge on the GAGs. To determine the genetic requirements for aggregate uptake, we individually knocked out the major genes of the HSPG synthesis pathway using CRISPR/Cas9 in HEK293T cells. Knockout of EXT1, EXT2 and EXTL3, N-sulfotransferase (NDST1), and 6-O-sulfotransferase (HS6ST2) significantly reduced tau uptake. α-Synuclein was not sensitive to HS6ST2 knockout. Good correlation between pharmacologic and genetic manipulation of GAG binding by tau and α-synuclein indicates specificity that may help elucidate a path to mechanism-based inhibition of transcellular propagation of pathology.
Clinically-guided mutation screening of two families with hereditary retinal disease
Authors: Li Jian , Yiming Aierken , Wang Ping 
Published: October 2017

AbstractHereditary retinal disease (HRD) is a series of Mendelian diseases affecting the retina in the eye. The genetic basis of HRD is very complicated, with more than 100 disease-causing genes being identified. Though NGS has allowed rapid and large-scale mutation screening of Mendelian disease, the cost of NGS still prevents its universal application all over the world, for an accurate molecular diagnosis. Here, by clinical guidance from patient phenotypes, we performed targeted molecular diagnosis by direct Sanger sequencing of the most likely candidate gene in two families diagnosed with HRD. Then we identified two novel protein-truncating variants in the gene CRB1. Our results demonstrated the notion that molecular diagnosis and clinical diagnosis can be mutually supplemented and clinically guided direct sequencing is a cost-effective approach for molecular diagnosis and subsequent genetic counseling.
Field evidence for manipulation of mosquito host selection by the human malaria parasite,Plasmodium falciparum
Authors: Vantaux Amélie , Yao Franck , Hien Domonbabele FdS , Guissou Edwige , Yameogo Bienvenue K. , Gouagna Louis-Clément , Fontenille Didier , Renaud François , Simard Frédéric , Constantini Carlo , Thomas Fréderic , Mouline Karine , Roche Benjamin , Cohuet Anna , Dabiré Kounbobr R , Lefèvre Thierry 
Published: October 2017

AbstractWhether the malaria parasitePlasmodium falciparumcan manipulate mosquito host choice in ways that enhance parasite transmission toward humans is unknown. We assessed the influence ofP. falciparumon the blood-feeding behaviour of three of its major vectors (Anopheles coluzzii, An. gambiaeandAn. arabiensis) in Burkina Faso. Host preference assays using odour-baited traps revealed no effect of infection on mosquito long-range anthropophily. However, the identification of the blood meal origin of mosquitoes showed that females carrying sporozoites, the mature transmissible stage of the parasite, displayed a 24% increase in anthropophagy compared to both females harbouring oocysts, the parasite immature stage, and uninfected individuals. Using a mathematical model, we further showed that this increased anthropophagy in infectious females resulted in a > 250% increase in parasite transmission potential, everything else being equal. This important epidemiological consequence highlights the importance of vector control tools targeting infectious females.
Periplasmic form of dipeptidyl aminopeptidase IV fromPseudoxanthomonas mexicanaWO24: purification, kinetic characterization, crystallization and X-ray crystallographic analysis
Authors: Roppongi Saori , Tateoka Chika , Fujimoto Mayu , Iizuka Ippei , Morisawa Saori , Nakamura Akihiro , Honma Nobuyuki , Suzuki Yoshiyuki , Shida Yosuke , Ogasawara Wataru , Tanaka Nobutada , Sakamoto Yasumitsu , Nonaka Takamasa 
Published: October 2017

Dipeptidyl aminopeptidase IV (DAP IV or DPP IV) fromPseudoxanthomonas mexicanaWO24 (PmDAP IV) preferentially cleaves substrate peptides with Pro or Ala at the P1 position [NH2-P2-P1(Pro/Ala)-P1′-P2′…]. For crystallographic studies, the periplasmic form of PmDAP IV was overproduced inEscherichia coli, purified and crystallized in complex with the tripeptide Lys-Pro-Tyr using the hanging-drop vapour-diffusion method. Kinetic parameters of the purified enzyme against a synthetic substrate were also determined. X-ray diffraction data to 1.90 Å resolution were collected from a triclinic crystal form belonging to space groupP1, with unit-cell parametersa= 88.66,b= 104.49,c = 112.84 Å, α = 67.42, β = 68.83, γ = 65.46°. Initial phases were determined by the molecular-replacement method usingStenotrophomonas maltophiliaDPP IV (PDB entry 2ecf) as a template and refinement of the structure is in progress.
Crystallization and X-ray diffraction analysis of native and selenomethionine-substituted PhyH-DI fromBacillussp. HJB17
Authors: Lu Fang , Zhang Bei , Liu Yong , Song Ying , Guo Gangxing , Feng Duo , Huang Huoqing , Yang Peilong , Gao Wei , Guo Sujuan , Yao Bin 
Published: October 2017

Phytases are phosphatases that hydrolyze phytates to less phosphorylatedmyo-inositol derivatives and inorganic phosphate. β-Propeller phytases, which are very diverse phytases with improved thermostability that are active at neutral and alkaline pH and have absolute substrate specificity, are ideal substitutes for other commercial phytases. PhyH-DI, a β-propeller phytase fromBacillussp. HJB17, was found to act synergistically with other single-domain phytases and can increase their efficiency in the hydrolysis of phytate. Crystals of native and selenomethionine-substituted PhyH-DI were obtained using the vapour-diffusion method in a condition consisting of 0.2 Msodium chloride, 0.1 MTris pH 8.5, 25%(w/v) PEG 3350 at 289 K. X-ray diffraction data were collected to 3.00 and 2.70 Å resolution, respectively, at 100 K. Native PhyH-DI crystals belonged to space groupC121, with unit-cell parametersa = 156.84,b = 45.54,c = 97.64 Å, α = 90.00, β = 125.86, γ = 90.00°. The asymmetric unit contained two molecules of PhyH-DI, with a corresponding Matthews coefficient of 2.17 Å3 Da−1and a solvent content of 43.26%. Crystals of selenomethionine-substituted PhyH-DI belonged to space groupC2221, with unit-cell parametersa = 94.71,b= 97.03,c= 69.16 Å, α = β = γ = 90.00°. The asymmetric unit contained one molecule of the protein, with a corresponding Matthews coefficient of 2.44 Å3 Da−1and a solvent content of 49.64%. Initial phases for PhyH-DI were obtained from SeMet SAD data sets. These data will be useful for further studies of the structure–function relationship of PhyH-DI.
Scandals from an island: Testing Anglo-American corporate governance frameworks
Authors: Uddin Shahzad , Jayasinghe Kelum , Ahmed Shaila 
Published: October 2017

PurposeThe purpose of this paper is to provide an account of banking scandals in relation to corporate governance (CG) failures in an emerging economy, arguing that Anglo-American ideas of CG are misplaced in traditional settings.Design/methodology/approachSemi-structured interviews were conducted with key stakeholders. Observations of annual general meetings (AGMs) and the personal working experience of one of the researchers, along with documentation, provided triangulating data on CG practices.FindingsThe authors have found that both of the banks studied had adopted CG practices contrary to the expectations of the Sri Lankan CG codes. Key features of CG practices that emerged from their investigations of these two scandals are ineffectual central bank regulations, familial boards of directors, ceremonial board meetings, biased auditing practices and manipulative AGMs, relying on traditional structures of accountability centred around families, kin and social networks.Research limitations/implicationsThe authors argue, drawing on Weber (1958, 1961, 1968, 1978), that the traditionalist culture mediates the process of rationality in bank governance codes and regulatory frameworks Therefore, practices fall far short of expectations.Originality/valueThe paper builds on the extended critique of shareholder-centric CG models and their transferability to alien contexts. It contributes to the CG studies calling for more appreciation of the need to move beyond the conventional view of CG problems as simply down to conflicts of interests. The authors complement and advance the decoupling debate in CG studies drawing on the Weberian notion of traditionalism.
Impulse buying intentions of young consumers from a hedonic shopping perspective
Authors: Dey Dipanjan Kumar , Srivastava Ankur 
Published: October 2017

Purpose
The purpose of this research paper is to examine predictors of impulsive buying intentions among youngsters from a hedonic shopping perspective. Recent theoretical work suggests that impulsive buying can function as a form of different hedonic shopping value dimensions such as fun, social interactions, novelty, escapism and outside appreciation.

Design/methodology/approach
The present research empirically tests a theoretical model of impulse buying intentions by examining the associations between hedonic shopping value dimensions and intentions in the presence of situational characteristics as moderators. A survey of 333 youngsters aged 15 to 23 is conducted using a structured questionnaire. Constructs are measured using established scales.

Findings
Results indicate that the impulsive buying intentions of youngsters are positively associated with all the five dimensions of hedonic shopping value. Situational characteristics of money and time availability positively moderate this relationship. Task definition negatively moderates the association between impulsive buying intention and hedonic shopping value dimensions.

Research limitations/implications
Two major theoretical implications result from this study. First, the study enabled the conceptualization of a theoretical framework of impulse buying intentions by including five dimensions of hedonic shopping value as important factors in young consumers’ impulse behavior buying intentions. Further, it includes the moderating effects of all the three aspects of situational characteristics in the same model.

Practical implications
The marketers can make use of the shopping value dimensions and the situational characteristics moderators to design and implement marketing strategies so that sales via impulse buying are maximized.

Originality/value
This study provides novel insights on the complex process of impulsive buying by youngsters by expanding the application of the hedonic shopping motives in the presence of situational factors as moderating variables.
Alternative explanations of relationship maintenance intention in mediation
Authors: Ha Hong-Youl , Kim Jang-Gyem , Chung Yongkyun 
Published: October 2017

PurposeThe purpose of this paper is to select the best model among alternative models explaining the relationship maintenance in mediation.Design/methodology/approachFour alternative models are employed in order to select best fit model through the test of each construct using Korean and Indonesian firm data.FindingsThe settlement model out of four alternative models is the best fit model in both Korea and Indonesia. The nexus of experience-settlement is not similar between Korea and Indonesia. The nexus of cost-saving-settlement is similar between two countries.Practical implicationsThe field manager and policy maker get useful information from the findings. In particular, Korea and Indonesia belong to different cultural clusters.Originality/valueThis study contributes to the mediation literature through the suggestion of hypothesized model of relationship maintenance intention in mediation.
Judicial Murder‐Suicides in Van Diemen's Land
Authors: Byard Roger W. , Maxwell Stewart Hamish 
Published: October 2017

AbstractOn the morning of December 17, 1827, nine convicts were executed by public hanging in Hobart Town, the capital of the British colony of Van Diemen's Land (now the Australian state of Tasmania). Two months previously they had drowned senior Constable George Rex on Small Island, which was part of the penal settlement at Macquarie Harbor, in front of five bound and gagged witnesses. They offered no defence at their trial. Examination of the Tasmanian colonial convict records shows that “suicide by lottery” involved convicts choosing two men, one to die and the other to kill him. The witnesses would earn a respite when taken away for the trial, and the murderer would be executed. “Death by gallows” could be considered a nineteenth‐century version of an orchestrated suicide reminiscent of more modern “death by cop.” This category of “judicial” murder‐suicide expands the range of contemporary classifications of dyadic deaths.
Minimally invasive esophagectomy in the lateral‐prone position: Experience of 124 cases in a single center
Authors: Ma Shaohua , Yan Tianshen , Liu Dandan , Wang Keyi , Wang Jingdi , Song Jintao , Wang Tong , He Wei , Bai Jie , Jin Liang 
Published: October 2017

BackgroundMinimally invasive esophagectomy was first introduced as a new technique for esophageal cancer treatment 20 years ago. Performing this procedure in the lateral‐prone position is the most appropriate method. Since May 2013, our center has performed 124 esophageal cancer operations using this procedure. Herein, we share our experience.MethodsWe retrospectively reviewed 124 consecutive patients who had received minimally invasive esophagectomy in the lateral‐prone position from May 2013 to June 2017. The procedure, operative variables, postoperative complications, and oncology outcomes were assessed.ResultsThe surgery was successful in all 124 patients; three cases converted to an abdominal opening procedure during surgery. The mean total lymph node harvest was 19.2: 12.9 in the thoracic cavity and 6.0 in the abdominal cavity. The average total operation duration was 376 minutes and blood loss was 156 mL. No mortality occurred within 30 postoperative days. Forty‐three cases of postoperative morbidity occurred in 38 patients (30.6%), including 11 anastomotic leakages (8.9%), 1 chyle leak (0.8%), 12 lateral recurrent nerve palsies (9.7%), 11 pulmonary complications (8.9%), and 8 other complications (6.5%). A learning curve indicated that blood loss, operation duration, and the number of lymph nodes harvested would improve with time.ConclusionsSurgical and oncological outcomes following minimally invasive esophagectomy for esophageal cancer were acceptable. There are some advantages to this technique compared to previous reports of opening procedures.
A systematic review of nonpharmacological prenatal interventions for pregnancy‐specific anxiety and fear of childbirth
Authors: Stoll Kathrin , Swift Emma Marie , Fairbrother Nichole , Nethery Elizabeth , Janssen Patricia 
Published: October 2017

AbstractBackgroundDespite a sharp increase in the number of publications that report on treatment options for pregnancy‐specific anxiety and fear of childbirth (PSA/FoB), no systematic review of nonpharmacological prenatal interventions for PSA/FoB has been published. Our team addressed this gap, as an important first step in developing guidelines and recommendations for the treatment of women with PSA/FoB.MethodsTwo databases (PubMed and Mendeley) were searched, using a combination of 42 search terms. After removing duplicates, two authors independently assessed 208 abstracts. Sixteen studies met eligibility criteria, ie, the article reported on an intervention, educational component, or treatment regime for PSA/FoB during pregnancy, and included a control group. Independent quality assessments resulted in the retention of seven studies.ResultsSix of seven included studies were randomized controlled trials (RCTs) and one a quasi‐experimental study. Five studies received moderate quality ratings and two strong ratings. Five of seven studies reported significant changes in PSA/FoB, as a result of the intervention. Short individual psychotherapeutic interventions (1.5‐5 hours) delivered by midwives or obstetricians were effective for women with elevated childbirth fear. Interventions that were effective for pregnant women with a range of different fear/anxiety levels were childbirth education at the hospital (2 hours), prenatal Hatha yoga (8 weeks), and an 8‐week prenatal education course (16 hours).ConclusionsFindings from this review can inform the development of treatment approaches to support pregnant women with PSA/FoB.
The cost of simplifying complex developmental phenomena: a new perspective on learning to walk
Authors: Lee Do Kyeong , Cole Whitney G. , Golenia Laura , Adolph Karen E. 
Published: October 2017

AbstractResearchers can study complex developmental phenomena with all the inherent noise and complexity or simplify behaviors to hone in on the essential aspects of a phenomenon. We used the development of walking as a model system to compare the costs and benefits of simplifying a complex, noisy behavior. Traditionally, researchers simplify infant walking by recording gait measures as infants take continuous, forward steps along straight paths. Here, we compared the traditional straight‐path task with spontaneous walking during 20 minutes of free play in 97 infants (10.75–19.99 months of age). We recorded infants’ footfalls on an instrumented floor to calculate gait measures in the straight‐path and free‐play tasks. In addition, we scored videos for other critical aspects of spontaneous walking—steps per bout, shape of walking path, and step direction. Studying infant walking during free play incurred no cost compared with the straight‐path task, but considerable benefits. Straight‐path gait was highly correlated with spontaneous gait and both sets of measures improved with walking age, validating use of the straight‐path task as an index of development. However, a large proportion of free‐play bouts were too short to permit standard gait measures, and most bouts were curved with omnidirectional steps. The high prevalence of these “non‐canonical” bouts was constant over development. We propose that a focus on spontaneous walking, the phenomenon we ostensibly wish to explain, yields important insights into the problems infants solve while learning to walk. Other areas of developmental research may also benefit from retaining the complexity of complex phenomena.