bluuebunny/crossref_metadata_2025_split huggingface dataset:
ПРИБЛИЖЕННЫЙ АЛГОРИТМ МОДЕЛИРОВАНИЯ СТАЦИОНАРНЫХ ДИСКРЕТНЫХ СЛУЧАЙНЫХ ПРОЦЕССОВ С ДВУМЕРНЫМИ РАСПРЕДЕЛЕНИЯМИ ПОСЛЕДОВАТЕЛЬНЫХ КОМПОНЕНТ В ВИДЕ СМЕСИ ГАУССОВСКИХ РАСПРЕДЕЛЕНИЙ
Authors: ОГОРОДНИКОВ В.А. , АКЕНТЬЕВА М.С. , КАРГАПОЛОВА Н.А. 
Published: October 2024

В работе представлен приближенный алгоритм моделирования стационарного дискретного случайного процесса с одномерными и двумерными распределениями его последовательных компонент в виде смеси двух гауссовских распределений. Алгоритм основан на комбинации метода условных распределений и метода исключения. Приведен пример применения алгоритма для моделирования временных рядов максимальной за сутки температуры воздуха.
The paper presents an approximate algorithm for modeling a stationary discrete random process with marginal and bivariate distributions of its consecutive components in the form of a mixture of two Gaussian distributions. The algorithm is based on a combination of the conditional distribution method and the rejection method. An example of application of the proposed algorithm for simulating time series of daily maximum air temperatures is given.
ЧАСТИЧНАЯ МНОГОМЕРНАЯ МОДЕЛЬ С ОШИБКАМИ В ПЕРЕМЕННЫХ И ЕЕ ПРИМЕНЕНИЕ В МОНИТОРИНГЕ ОСЕДАНИЯ ГРУНТА
Authors: ВАН Ц. , ХУ Ф. 
Published: October 2024

С целью решения проблемы, связанной с тем, что матрица коэффициентов многомерной модели c ошибками в переменных (ММОП) содержит постоянные столбцы, модель ММОП расширена до частичной многомерной модели с ошибками в переменных (Ч-ММОП) и предложен новый алгоритм модели Ч-ММОП, основанный на принципе частичной модели с ошибками в переменных (Ч-МОП) и непрямой корректировке. Алгоритм прост и легко реализуем. Для проверки используется пример преобразования координат, а результаты сравниваются с существующим алгоритмом модели ММОП; они показывают эффективность предлагаемого алгоритма. Наконец, алгоритм Ч-ММОП применяется к многоточечной серой модели (МСМ(1,N)) мониторинга оседания грунта. Результаты показывают, что модель Ч-ММОП, предлагаемая в данной статье, лучше учитывает влияние ошибок точек мониторинга, а результаты хорошо соответствуют реальной ситуации.
Aiming at the problem that the coefficient matrix of multivariate errors-in-variables (MEIV) model contains constant columns, the MEIV model is extended to partial multivariate errors-in-variables (P-MEIV), and the new algorithm of P-MEIV model is proposed based on the principle of partial errors-in-variables (PEIV) model and indirect adjustment. The algorithm is simple and easy to implement. An example of coordinate transformation is used for verifying, and the results are compared with the existing MEIV model algorithm, which shows the effectiveness of the proposed algorithm. Finally, the P-MEIV algorithm is applied to the multi-point grey model (MGM(1,N)) of settlement monitoring. The results show that the P-MEIV model proposed in this paper can better consider the influence of monitoring point errors, and the estimated results are in good agreement with the actual situation.
КРИТЕРИИ РАЗРЕШИМОСТИ АСИММЕТРИЧНЫХ РАЗНОСТНЫХ СХЕМ ПРИ ВЫСОКОТОЧНОЙ АППРОКСИМАЦИИ ГРАНИЧНЫХ УСЛОВИЙ
Authors: ПААСОНЕН В.И. 
Published: October 2024

В работе исследуется технология расчета разностных задач с внутренними граничными условиями баланса потоков, построенными с помощью односторонних многоточечных разностных аналогов первых производных произвольного порядка точности. Предлагаемая технология одинаково подходит для любых типов решаемых дифференциальных уравнений и допускает однотипную реализацию при любых порядках точности. Она, в отличие от аппроксимаций, опирающихся на продолженную систему уравнений, не приводит к осложнениям при расщеплении многомерных задач на одномерные. Сформулированы достаточные условия разрешимости и устойчивости реализации алгоритмов методом прогонки для граничных условий произвольного порядка точности. Доказательство основано на приведении многоточечных граничных условий к виду, не нарушающему трехдиагональную структуру матриц, и установлении условий диагонального преобладания в преобразованных строках матрицы, соответствующих внешним и внутренним граничным условиям.
In this paper we study the technology of calculating difference problems with internal boundary conditions of flow balance constructed by means of one-sided multipoint difference analogs of first derivatives of arbitrary order of accuracy. The proposed technology is equally suitable for any type of differential equations to be solved and admits a uniform realization at any order of accuracy. It, unlike approximations based on the continued system of equations, does not lead to complications in splitting multidimensional problems into one-dimensional ones. Sufficient conditions of solvability and stability of the realization of algorithms by the run method for boundary conditions of arbitrary order of accuracy are formulated. The proof is based on the reduction of multipoint boundary conditions to a form that does not violate the tridiagonal structure of matrices, and the establishment of the conditions of diagonal dominance in the transformed matrix rows corresponding to the external and internal boundary conditions.
GALNT3 in Ischemia–Reperfusion Injury of the Kidney
Authors: Wu Wenwen , Fu Ying , Li Honglin , Xiang Yu , Zeng Yuqing , Cai Juan , Dong Zheng 
Published: October 2024

Key Points

N-acetylgalactosaminyltransferase-3 (GALNT3) was downregulated in both ischemic AKI and cisplatin nephrotoxicity.GALNT3 played a protective role in renal tubular cells, and its downregulation contributed to AKI.Mechanistically, GALNT3 protected kidney tubular cells at least partially through O-glycosylation of EGF receptor.

Background
Damages to subcellular organelles, such as mitochondria and endoplasmic reticulum, are well recognized in tubular cell injury and death in AKI. However, the changes and involvement of Golgi apparatus are much less known. In this study, we report the regulation and role of N-acetylgalactosaminyltransferase-3 (GALNT3), a key enzyme for protein glycosylation in Golgi apparatus, in AKI.

Methods
AKI was induced in mice by renal ischemia–reperfusion injury or cisplatin. In vitro, rat kidney proximal tubular cells were subjected to hypoxia/reoxygenation (H/R) injury. To determine the role of GALNT3, its specific inhibitor T3inh-1 was tested in mice, and the effects of GALNT3 overexpression as well as knockdown were examined in the rat renal proximal tubular cells. EGF receptor (EGFR) activation was induced by recombinant EGF or by overexpressing EGFR.

Results
GALNT3 was significantly decreased in both in vivo and in vitro models of AKI induced by renal ischemia–reperfusion injury and cisplatin. T3Inh-1, a specific GALNT3 inhibitor, exacerbated ischemic AKI and suppressed tubular cell proliferation in mice. Moreover, knockdown of GALNT3 increased apoptosis during H/R treatment in rat renal proximal tubular cells, whereas overexpression of GALNT3 attenuated H/R-induced apoptosis, further supporting a protective role of GALNT3. Mechanistically, GALNT3 contributed to O-glycosylation of EGFR and associated EGFR signaling. Activation or overexpression of EGFR suppressed the proapoptotic effect of GALNT3 knockdown in H/R-treated rat renal proximal tubular cells.

Conclusions
GALNT3 protected kidney tubular cells in AKI at least partially through O-glycosylation of EGFR.
De l’inégalité objectivisée à l’inégalité ressentie et aux peurs qu’elle suscite: les réfugiés pris au piège de l’identité
Authors: Moirand Sophie 
Published: October 2024

Résumé: Cet article interroge les relations entre identité et inégalité dans les récits publiés par la presse française, lors de la crise des migrants (ou réfugiés) en Europe (2015-2016). Après un rapide recensement des mots qui disent l’(in)égalité depuis le Siècle des Lumières jusqu’aux études récentes de sciences humaines, l’analyse s’attache à construire le profil sémantique de mots associés rencontrés dans les médias lors de micro-événements liés à cette crise, à partir de leurs cotextes (mots et constructions), telle l’inscription de la peur dans les discours représentés (faire peur vs avoir peur). Cette étude conduit à conclure: d’une part que ce qui sous-tend les formes discursives de clivage identitaire, c’est en fait “la peur de perdre son identité”; d’autre part que l’inégalité “ressentie” à travers une religion ou une ethnie remet en cause l’identité républicaine qui est, historiquement et toujours, celle de la France.Mots-clés: discours des médias; émotion; identité; inégalité; migrant; peur; profil sémantique; sémantique discursive.Abstract: This paper examines the relations between identity and inequality in French newspaper discourse about the migrants’ or refugees’ events in Europe (2015-2016). After compiling the words of (in)equality since the 18th century to recent studies of human and social sciences, the analysis focuses on building the semantic profile of keywords linked to these events within its cotextual relations, as words and constructions of fear in media discourses (cause fear vs feel fear). This study leads to two conclusions: what underlies the discursive forms of identity cleavage is “the fear of losing its own identity”; inequality felt through religion or ethnicity undermines the republican identity, that is, historically and also, the identity of France.Keywords: French Daily Press; Emotion; Identity; Inequality; Migrant; Fear; Semantic Profile; Discursive Semantics.
La figure du “jeune des banlieues” en France: Genèse, mutations et déterritorialisation
Authors: Lochard Guy 
Published: October 2024

Résumé: La “question urbaine” hante depuis très longtemps l’imaginaire collectif français et elle s’est condensée depuis près d’un siècle sur la figure du jeune déviant urbain. Cet article s’attache à mettre en évidence la genèse puis les transformations de ce personnage stéréotypique ainsi que la construction et les déplacements de grandes configurations actantielles qu’il contribue à structurer. Il souligne l’importante mutation intervenue depuis une trentaine d’années avec son ethnicisation. Puis, plus récemment, avec l’apparition de la figure du djihadiste qui est sujette à une forme de déterritorialisation, la menace liée à cette population juvénile pouvant désormais siéger dans des micro-espaces résidentiels des grandes agglomérations ou dans des bourgades provinciales. Faut-il conclure à une dilution de la “question des banlieues” en France? L’auteur reste interrogatif devant le surgissement de moments discursifs comme la récente “affaire Benzema”, relative à la non-sélection en équipe de France de football d’un joueur-vedette d’origine maghrébine. Mots-clés: marginalité urbaine; imaginaire urbain; stéréotypisation; médias; cinéma.Abstract: The “urban issue” haunted for a long time the French collective imagination and has condensed for nearly a century on the stereotypical figure of the young urban deviant. The article attempts to highlight the origins and transformations of this stereotypical character as well as the construction and displacement of large actantial configurations that it helps to structure. It stresses the important transformation that has taken place over thirty years with his ethnicization. Then, more recently, with the appearance of the character of the jihadist — who is subject to a form of deterritorialization — the threat related to this young population may henceforth sit in residential micro areas of large cities or in provincial towns. Must we conclude that there is a dilution of the “question of the suburbs” in France? The author remains questioning when faced with the emergence of discursive moments such as the recent “Benzema affair”, when a star football player of North African origin was not selected for the France team.Keywords: Urban Marginality; Urban Imaginary; Stereotyping; Media; Movies.
Conceptual model of the technology for calculating the similarity threshold of two audio sequences
Authors: Холєв Владислав Олександрович 
Published: October 2024

The paper is focused on the pressing problem of speaker verification by means of voice time series comparison. The aim of this paper is to determine the orders of mel-frequency cepstral coefficients that most accurately describe the difference, between an authentic voice and an artificially generated copy for their further use as input to a neural network model in a resource-limited environment. To achieve this goal, the following tasks were accomplished: a conceptual model of the technology for determining the similarity threshold of two audio series was developed; the orders of fine-frequency cepstral coefficients with the most characteristic differences between the recording and the generated voice were determined on the basis of neural network analysis; an experimental study of the dependence of the execution time and computational load on the created feature vector when assessing the degree of similarity of two time series was conducted; and the optimal similarity threshold was determined on the basis of the chosen dataset. The developed model of the technology for determining the similarity threshold was tested on a dataset that is a combination of the DEEP-VOICE dataset and our own dataset. The demonstrated result of applying the developed technology showed an increase of 43% when using the specified MFCCs compared to using all of them. Based on experimental studies, the DTW acceptance threshold was set at 0.37.
CARACTERIZACION DE PACIENTES CON CÁNCER GÁSTRICO EN EL HOSPITAL UNIVERSITARIO SAN RAFAEL DE TUNJA, 2015 - 2020.
Authors: Ospina Diaz Juan Manuel , Ospina Ariza Laura Victoria , Hernández Perilla Dary Luz , Ortiz Cruz David Leonardo 
Published: October 2024

Contexto: El cáncer gástrico es un problema de salud pública con gran impacto, que alcanzó 1.090.000 casos y 769.000 muertes en el año 2020, a nivel mundial; es la tercera causa de muerte por cáncer en el mundo. Objetivo: Determinar las características clínicas, patológicas y sociodemográficas en pacientes con cáncer gástrico atendidos en el Hospital Universitario San Rafael de Tunja entre el año 2015 y el año 2020. Materiales y métodos: estudio observacional, descriptivo de corte transversal. De los registros del Hospital San Rafael de Tunja se revisaron las historias clínicas de 138 pacientes, ingresados con diagnóstico de carcinoma gástrico, en el período 2015 – 2020. Resultados: edad media 61,7 años, 63,4% hombres; 52,7% provenientes de área rural; 25% con déficit nutricional por índice de masa corporal; 59,4% ya presentaba metástasis, las más frecuentes a Peritoneo, hígado y pulmón; Solo fue posible intervenir quirúrgicamente al 25,5% de los casos; Al momento de evaluación de las historias clínicas había fallecido el 43,5% de los pacientes. Conclusiones: Las condiciones ambientales, culturales y socioeconómicas generan escenarios favorables para aumento de la incidencia de cáncer gástrico de tipo adenocarcinoma, lo que lleva a prever un aumento progresivo de los mismos. Es recomendable establecer protocolos de diagnóstico y capacitación para potencializar el diagnóstico precoz, que haga de la cirugía una opción curativa más efectiva y mejore el pronóstico de los pacientes. Sería conveniente que a nivel regional se estructure un centro observatorio de cáncer que haga vigilancia epidemiológica y georreferenciación de los casos para mejorar las condiciones de seguimiento y control
Palabras Clave: Adenocarcinoma; Gastrectomía; Prevalencia; Metástasis neoplásica. (DeCS)
Characterisation and statistical modelling of shear strength in 12 hardwood timber species from the Congo Basin
Authors: NDIAPI Olivier , NJANKOUO Jacques Michel , OHANDJA Louis Max Ayina , GERARD Jean 
Published: October 2024

Shear strength is a wood property which is fundamental to the design of wood-based products and constructions. This property cannot be predicted at present for lack of sufficient knowledge, mainly because of the large number of timber species that occur in the Congo Basin. The main aim of this study was to provide a preliminary qualification of shearing in Congo Basin timber species, with consideration for its variability. For this purpose, we studied 12 timber species with very different properties, from the least dense to the densest. Their shear strength was determined experimentally using European standards specifications, on the scale of the wood material used. A statistical analysis was conducted. To reduce shear strength variability, the species were assigned to four distinct clusters defined according to FCBA Institute specifications. With a view to developing allowable design stresses to facilitate decision-making, we evaluated the relative goodness-of-fit of five probabilistic shear strength distributions (normal, lognormal, exponential, Weibull 2 parameters and Weibull 3 parameters) that are used in wood-related applications. The results of geometric regression (R2 = 0.81) show that shear strength is well correlated with density. Shear strength can be more reliably predicted with the three-parameter Weibull distribution than with the other distributions. The findings of this study open up new prospects to be considered for the design of wood-based products with regard to shear, when using tropical timber species from the Congo Basin.
PENINGKATAN KETERAMPILAN KOMUNIKASI SISWA KELAS XI OTOMOTIF 3 MELALUI STRATEGI PEMBELAJARAN KOOPERATIF TIPE GALLERY WALK PADA MATA PELAJARAN PENDIDIKAN PANCASILA
Authors: Dini Anggi Arum , Muhibbin Ahmad 
Published: October 2024

<p>Penelitian ini bertujuan untuk mengetahui keefektifan strategi kooperatif tipe <em>gallery wal</em>k dalam meningkatkan keterampilan komunikasi pada mata pelajaran pendidikan pancasila siswa di kelas XI Otomotif 3 SMK Muhammadiyah Kartasura. Jenis penelitian ini adalah Penelitian Tindakan Kelas. Subjek penelitian adalah peserta didik kelas XI Otomotif 3 SMK Muhammadiyah Kartasura dengan objek penelitian keterampilan komunikasi. Instrumen yang digunakan adalah lembar observasi dan dokumentasi. Hasil penelitian menunjukkan bahwa terjadi peningkatan keterampilan komunikasi peserta didik pada siklus I ke siklus II. Pada siklus I persentase keterampilan komunikasi peserta didik hanya mencapai 22,4 % dalam kategori kurang terampil. Pada siklus II keterampilan komunikasi peserta didik meningkat mencapai 78% dalam kategori terampil.</p><strong>Kata Kunci: </strong><em>strategi kooperatif, gallery walk </em>
Enhancing Methodological Approaches for Studying Health Effects of High-Concentration THC Products
Authors: Li Tianjing , Wang George Sam , Bero Lisa , Brooks-Russell Ashley , Tung Gregory , Samet Jonathan M. 
Published: October 2024

For public health protection, informed decision-making relies on having a robust foundation of evidence concerning risks and their prevention. Application of an evidence-based framework depends on the availability of pertinent, scientifically sound data generated by well-directed and valid research endeavors. In this essay, we address the current state of research in humans and the evidential base concerning high-concentration delta-9-tetrahydrocannabinol (delta-9-THC) products, which are readily available in the United States. Furthermore, we explore the intricate challenges faced in carrying out research on these products, which reflect the full range of study design issues: measurement of exposure and outcomes, confounding, selection bias, and the generalizability of findings. We offer recommendations to guide future research toward providing more informative evidence. By following these recommendations, researchers and funders on this emerging topic could move toward generating the valid and comprehensive evidence needed to effectively inform public health initiatives and guide policy decisions regarding high-concentration delta-9-THC products and their use. The urgency of generating such evidence cannot be overstated, given the widespread legalization and increasing availability and use of these products. ( Am J Public Health. 2024;114(S8):S639–S644. https://doi.org/10.2105/AJPH.2024.307724 )
Coupled Modeling of Computational Fluid Dynamics and Granular Mechanics of Sand Production in Multiple Fluid Flow
Authors: Khamitov Furkhat , Shabdirova Ainash , Kozhagulova Ashirgul , Nguyen Hop Minh , Zhao Yong 
Published: October 2024

Summary
Sand production is a significant issue in oil and gas fields with poorly consolidated formations, often involving the multiphase flow of reservoir fluids and solid particles. The multiscale mechanisms of sand production, particularly fluid flow and particle movement, remain poorly understood. This study investigates these mechanisms using a coupled computational fluid dynamics and discrete element method (CFD-DEM) modeling approach. Single and multiple fluid flows of water and heavy oil were simulated with increasing fluid injection velocities, leading to different sand production patterns. The simulation results were compared with experimental results from a large cylindrical specimen of weak artificial sandstone under similar loading conditions. The multiphase conditions created various localized flow and deformation patterns that influenced both fluid and solid production, resulting in shorter transient sand production periods. Microstructures and phenomena such as fingering and water coning were observed, associated with a critical flow rate below which oil displacement was uniform and no water breakthrough occurred. Higher fluid injection velocities and fluid viscosities resulted in greater drag forces, leading to progressive damage zones and explaining the occurrence of single or multiple staged sand production events. The evolution of the microscopic granular structure was visualized under the effect of transient sand production.
Study Protocol: SMILE - Stereotactic Multiple Fraction Radiotherapy for Non-Spine Bone Metastases
Authors: Foerster Robert , Zwahlen Daniel Rudolf , Schroeder Christina , Windisch Paul , Halatsch Marc , Alfieri Alex , Meier Christoph , Hemmatazad Hossein , Aebersold Daniel M. , Buchali André , Habermehl Daniel , Batifi Nidar 
Published: October 2024

Abstract

Background: The SMILE study addresses a significant need in palliative oncology by evaluating the non-inferiority of a shortened, 3-fraction stereotactic body radiotherapy (SBRT) schedule against the traditional 5-fraction approach for non-spine bone metastases in terms of pain control. Optimizing SBRT could significantly enhance the quality of life for patients by providing effective pain relief while minimizing treatment sessions.
Methods: This international, multicenter phase III trial will randomize 162 patients to receive either a 3-fraction regimen (9 Gy per fraction) or a standard 5-fraction regimen (7 Gy per fraction). Outcomes, assessed at 3 months post-treatment, will focus on pain response, quality of life, and control of metastasis. With a hypothesis-driven design, the study will incorporate intent-to-treat and per-protocol analyses, incorporating appropriate measures for data integrity and handling of missing information.
Discussion: If the 3-fraction SBRT regimen demonstrates non-inferiority, it could streamline palliative care protocols, reduce patient burden, and set a new standard for treatment, reflecting a patient-centered approach in palliative radiation oncology.
Trial Registration: The trial has been registered prospectively on ClinicalTrials.gov under the identifier NCT05406063, as of May 3, 2022.
WITHDRAWN: Deciphering PCSK9 and LDLR Gene Expression in Coronary Artery Disease Patients: Implications for Blood Lipid Regulation
Authors: Zahid Aqsa , Batool Andleeb , Khan Muhammad Ajmal , Ahmad Ajaz , Ullah Amin , Wajid Abdul 
Published: October 2024

Abstract

The full text of this preprint has been withdrawn by the authors due to author disagreement with the posting of the preprint. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.