bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oceanic Impetus for Convective Onset of the Madden–Julian Oscillation in the Western Indian Ocean
Authors: Rydbeck Adam V. , Jensen Tommy G. 
Published: February 2017

Abstract
A theory for intraseasonal atmosphere–ocean–atmosphere feedback is supported whereby oceanic equatorial Rossby waves are partly forced in the eastern Indian Ocean by the Madden–Julian oscillation (MJO), reemerge in the western Indian Ocean ~70 days later, and force large-scale convergence in the atmospheric boundary layer that precedes MJO deep convection. Downwelling equatorial Rossby waves permit high sea surface temperature (SST) and enhance meridional and zonal SST gradients that generate convergent circulations in the atmospheric boundary layer. The magnitude of the SST and SST gradient increases are 0.25°C and 1.5°C Mm−1 (1 megameter is equal to 1000 km), respectively. The atmospheric circulations driven by the SST gradient are estimated to be responsible for up to 45% of the intraseasonal boundary layer convergence observed in the western Indian Ocean. The SST-induced boundary layer convergence maximizes 3–4 days prior to the convective maximum and is hypothesized to serve as a trigger for MJO deep convection. Boundary layer convergence is shown to further augment deep convection by locally increasing boundary layer moisture. Warm SST anomalies facilitated by downwelling equatorial Rossby waves are also associated with increased surface latent heat fluxes that occur after MJO convective onset. Finally, generation of the most robust downwelling equatorial Rossby waves in the western Indian Ocean is shown to have a distinct seasonal distribution.
Framingham Risk Score as a Prognostic Predictor of Sudden Sensorineural Hearing Loss: A Preliminary Study
Authors: Chang Young-Soo , Choi Ji Eun , Ahn Jungmin , Ryu Nam-Gyu , Moon Il Joon , Hong Sung Hwa , Cho Yang-Sun , Chung Won-Ho 
Published: February 2017

Objectives/Hypothesis: Predicting the prognosis of idiopathic sudden sensorineural hearing loss (ISSHL) remains challenging. This investigation aimed to apply Framingham Risk Scores (FRS) to assess the combination of prognostic factors following ISSHL and investigate the predictive role of FRS in patients with multiple comorbidities including hypertension, diabetes, and hyperlipidemia. Study design: Retrospective study. Methods: Twenty-one patients presenting with unilateral idiopathic sudden sensorineural hearing loss and multiple comorbidities were surveyed. Framingham Risk Score was calculated, and patients were assigned into high-risk (FRS ≥20%) and low-risk (FRS <20%) groups. Mean pure tone audiometry (PTA) threshold of both groups and hearing outcomes following established criteria were investigated. All patients were treated with the same protocol of oral methylprednisolone. Results: Overall successful recovery rate (complete + marked recovery) was 23.81%. The mean PTA threshold of the low-risk group showed significant improvement (mean PTA ± standard error, SE: pretreatment, 73.23 ± 11.80; posttreatment, 54.89 ± 10.25, P = .002), while the high-risk group did not show significant improvement in mean PTA threshold (mean PTA ± SE: pretreatment, 71.94 ± 11.77; posttreatment, 68.89 ± 12.81, P = .73). Conclusion: Framingham Risk Scores may be useful in predicting outcomes for ISSHL patients with multiple comorbidities.
Factors Associated With Infectious Laryngitis: A Retrospective Review of 15 Cases
Authors: Thomas Carissa M. , Jetté Marie E. , Clary Matthew S. 
Published: February 2017

Objectives: To identify the culturable microbes associated with infectious laryngitis and outline effective treatment strategies. Methods: This is a retrospective chart review of adult patients with persistent dysphonia plus evidence of laryngeal inflammation who underwent biopsy for culture at a tertiary care medical center. Demographic factors, symptoms as reported on validated patient assessment tools, past medical history, social history, culture results, and treatment duration and response were reviewed. Results: Fifteen patients with infectious laryngitis were included in this study. Culture results demonstrated Methicillin-sensitive Staphylococcus aureus (MSSA), Methicillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, Serratia marcescens, and “normal respiratory flora.” In most patients, multiple courses of prolonged antibiotics were needed to treat MSSA or MRSA. Infections associated with other microbes resolved with a single course of antibiotics. Conclusions: In this population, infectious laryngitis is defined as colonization with bacteria not found in the previously characterized laryngeal microbiome of benign vocal fold lesions. In suspected cases of infectious laryngitis, culture is recommended, by biopsy if needed. For MSSA- and MRSA-associated laryngitis, an extended course of antibiotics may be necessary for symptom improvement and resolution of laryngeal inflammation. However, the optimal treatment regimen has yet to be defined and will require larger, prospective studies.
The Yoyo-Man
Authors: Laumond Jean–Paul , Benallegue Mehdi , Carpentier Justin , Berthoz Alain 
Published: February 2017

The paper reports on two results issued from a multidisciplinary research action exploring the motor synergies of anthropomorphic walking. By combining the biomechanical, neurophysiology, and robotics perspectives, it is intended to better understand human locomotion with the ambition to better design bipedal robot architectures. The motivation of the research starts from the simple observation that humans may stumble when following a simple reflex-based locomotion on uneven terrains. The rationale combines two well established results in robotics and neuroscience, respectively: passive robot walkers, which are very efficient in terms of energy consumption, can be modeled by a simple rotating rimless wheel; humans and animals stabilize their head when moving. The seminal hypothesis is then to consider a wheel equipped with a stabilized mass on top of it as a plausible model of bipedal walking. The two results presented in the paper support the hypothesis. From a motion capture data basis of twelve human walkers, we show that the motions of the feet are organized around a geometric center, which is the center of mass, and is surprisingly not at the hip. After introducing a ground texture model that allows us to quantify the stability performance of walker control schemes, we show how compass-like passive walkers are better controlled when equipped with a stabilized 2-degree-of-freedom moving mass on top of them. The center of mass and head then play complementary roles that define what we call the Yoyo-Man. Beyond the two results presented in the paper, the Yoyo-Man model opens new perspectives to explore the computational foundations of anthropomorphic walking.
Association of hypertension and treatment outcomes in advanced stage non-small cell lung cancer patients treated with bevacizumab or non-bevacizumab containing regimens
Authors: Yan Lily Z , Dressler Emily V , Adams Val R 
Published: February 2017

Background Studies suggest that bevacizumab-induced hypertension is prognostic of better outcomes in bevacizumab-treated patients with metastatic colorectal, HER2-negative breast, kidney, and pancreatic cancer. Few have examined this correlation in metastatic non-small cell lung cancer and evaluated whether hypertension independent of bevacizumab can improve the treatment outcomes. Objectives The primary objective was to determine the effect of hypertension on the overall response of advanced non-small cell lung cancer patients from start of the first-line chemotherapy to maintenance therapy. Secondary objectives include the effect of hypertension on the overall survival in all patients and on the overall response in bevacizumab-treated patients. Methods A retrospective chart review for a single institution was conducted from 2008 to 2013 on all patients with advanced non-squamous non-small cell lung cancer who received ≥ 1 cycle of combination chemotherapy. Patients were divided into hypertension versus no hypertension and into bevacizumab versus non-bevacizumab groups. Results Of the 188 advanced non-small cell lung cancer patients evaluated, 62 were treated with bevacizumab-containing regimens. The mean age at diagnosis was 58 years in both the groups. Hypertension independent of bevacizumab did not lead to improved treatment outcomes. However, in the bevacizumab subgroup, hypertensive patients had significantly higher response rates versus non-hypertensive patients (36.7% vs. 12.5%; p = 0.02). There was no significant difference in the overall survival between hypertensive versus non-hypertensive patients. Conclusion While hypertension alone did not significantly improve the treatment outcomes, hypertension in bevacizumab-treated patients with metastatic non-small cell lung cancer led to significantly improved responses. Further prospective studies are needed to confirm the association of hypertension with improved treatment outcomes in metastatic NSCLC.
Assessing analgesia equivalence and appetite following alfaxalone- or ketamine-based injectable anesthesia for feline castration as an example of enhanced recovery after surgery
Authors: Armstrong Tatum , Wagner Marika C , Cheema Jagjit , Pang Daniel SJ 
Published: February 2017

Objectives The primary study objective was to assess two injectable anesthetic protocols, given to facilitate castration surgery in cats, for equivalence in terms of postoperative analgesia. A secondary objective was to evaluate postoperative eating behavior. Methods Male cats presented to a local clinic were randomly assigned to receive either intramuscular ketamine (5 mg/kg, n = 26; KetHD) or alfaxalone (2 mg/kg, n = 24; AlfHD) in combination with dexmedetomidine (25 μg/kg) and hydromorphone (0.05 mg/kg). All cats received meloxicam (0.3 mg/kg SC) and intratesticular lidocaine (2 mg/kg). Species-specific pain and sedation scales were applied at baseline, 1, 2 and 4 h postoperatively. Time taken to achieve sternal recumbency and begin eating were also recorded postoperatively. Results Pain scale scores were low and showed equivalence between the treatment groups at all time points (1 h, P = 0.38, 95% confidence interval [CI] of the difference between group scores 0–0; 2 h, P = 0.71, 95% CI 0–0; 4 h, P = 0.97, 95% CI 0–0). Four cats crossed the threshold for rescue analgesia (KetHD, n = 1; AlfHD, n = 3). At 1 h, more cats in the KetHD (65%) group than in the AlfHD (42%) group were sedated, but statistical significance was not detected ( P = 0.15, 95% CI −1 to 0). Most AlfHD cats (88%) began eating by 1 h vs 65% of KetHD cats ( P = 0.039). Time to recover sternal recumbency did not differ between groups ( P = 0.86, 95% CI −14.1 to 11.8). Conclusions and relevance These results show that AlfHD and KetHD provide equivalent analgesia as part of a multimodal injectable anesthetic protocol. Alfaxalone is associated with an earlier return to eating.
Decision Algorithms for the Retreatment with Viscosupplementation in Patients Suffering from Knee Osteoarthritis: Recommendations from the EUROpean VIScosupplementation COnsensus Group (EUROVISCO)
Authors: Raman Raghu , Henrotin Yves , Chevalier Xavier , Migliore Alberto , Jerosch Jörg , Montfort Jordi , Bard Hervé , Baron Dominique , Richette Pascal , Conrozier Thierry 
Published: February 2017

Background Viscosupplementation (VS) is a symptomatic treatment of knee osteoarthritis. Although systematic reviews of its repeat use showed favorable benefit/risk ratio, no study has focused on the indication of retreatment. Methods A task force was created to look at issues regarding retreatment with VS in knee osteoarthritis. An attempt was made to reach consensus on several issues: (1) to define treatment “success” and “failure,” (2) to determine when to retreat patients successfully treated by a previous VS, (3) to determine how to retreat patients in whom VS failed, (4) to define what to do in case of adverse reaction following previous VS, and (5) to examine the interests of soluble biomarkers to manage retreatment. After debate and review of literature the working group voted on 88 issues. Two “decision trees” were built based on the results of the votes. Results In case of failure, the authors draw attention to the need of a rigorous clinical and radiological analysis, and consider evidence-based medicine. When VS was previously successful, retreatment can be considered after recurrence or increase in pain. However, in subjects with high risk of disease progression, in young patients, and in professional sportsmen, retreatment could be considered systematically, because of the probability of hyaluronic acid to slow osteoarthritis progression. Evidence on soluble biomarkers was not considered as enough strong to support their use as decision tools for patient retreatment. Conclusion The decision algorithms are intended to facilitate consideration of the therapeutic options, in patients with knee osteoarthritis previously treated with VS.
Is surgery always indicated in rachitic coronal knee deformities? Our experience in 198 knees
Authors: Prakash Jatin , Mehtani Anil , Sud Alok , Reddy Baccha K 
Published: February 2017

Introduction: Defective mineralization of osteoid matrix prior to physeal closure causes rickets. Poor calcification of the cartilage matrix in the zone of provisional calcification causes flattened skull, rachitic rosary, bowed legs, coxa vara and brittle bones. The recent literature has seen an increase in the incidence of the disease in both developing and developed nations. We evaluated behaviour of lower limb deformities due to nutritional rickets in 117 patients. Materials and methods: A prospective study was conducted from January 2009 to December 2011 for clinical and radiological evaluation of knee deformities in nutritional rickets. A total of 117 patients with 198 coronal plane knee deformities between 2 years and 12 years age of rickets were enrolled in this study. Results: In our study, there were 65 genu varum and 133 genu valgum deformities. Seven genu varum (10.7%) and 37 genu valgum (28%) deformities were regarded as failure. Fifty eight genu varum got corrected completely obtaining an average of 5° of valgum in an average of 6.3 months. The average rate of spontaneous correction was 1.9° a month. Ninety six valgum got corrected obtaining an average of 4.7 valgum in an average of 13.3 months. The average rate of spontaneous correction was 0.92° a month. Conclusion: Most of the rachitic deformities get corrected with age. Genu varum is having better chances and a faster rate of correction as compared with genu valgum. Early surgery may be indicated in late presenting cases. We believe varum above 4 years and 18° of valgum above 9 years usually do not correct and may require surgical intervention.
The Anterolateral Ligament: An Anatomic Study on Sex-Based Differences
Authors: Daggett Matt , Helito Camilo , Cullen Matthew , Ockuly Andrew , Busch Kyle , Granite Joseph , Wright Barth , Sonnery-Cottet Bertrand 
Published: February 2017

Background: The anterolateral ligament (ALL) has been shown to have an important role in rotatory stability of the knee. While there is abundant research on sex-based differences related to anterior cruciate ligament (ACL) rupture, there is a paucity of literature related to such differences in the ALL. Purpose: To define any sex-based differences in the ALL with regard to length, width, and thickness. Study Design: Descriptive laboratory study. Methods: The ALL was initially evaluated in 165 unpaired knees (92 males and 65 females after exclusion criteria applied). The length, width, and thickness of the ALL were measured using a digital caliper. Width and thickness were measured at the joint line just superior to the lateral meniscus. The Mann-Whitney test and Student t tests were used to compare measurements between males and females. The Pearson product-moment correlation was subsequently used to determine the correlation between height and weight and the statistically different morphometric variables. Results: The mean (±SD) thickness of the ALL in males was 2.09 ± 0.56 mm, almost twice as thick as females (1.05 ± 0.49 mm; P = 8.8 × 10−20). There was also a statistically significant difference in ALL length ( P = 3.8 × 10−7), but no significant difference was found for width. A moderate association was found between donor height and ALL thickness and length. Conclusion: The anatomic measurements of the ALL demonstrate a difference between sexes, and the ALL is significantly thicker in males than females. Clinical Relevance: As the role of the ALL in rotatory stability of the knee becomes better understood, the difference in the thickness of the ALL we have found between the sexes may be another factor why female athletes have an increased incidence of ACL rupture compared with males. This may also help explain why females have issues with knee laxity and rotatory instability.
Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development
Authors: Subramaniam Saravanan , Jurk Kerstin , Hobohm Lukas , Jäckel Sven , Saffarzadeh Mona , Schwierczek Kathrin , Wenzel Philip , Langer Florian , Reinhardt Christoph , Ruf Wolfram 
Published: February 2017

Key PointsMyeloid cell TF-dependent venous thrombosis is under control of PDI and the complement cascade. C5 deficiency reduces fibrin formation and leukocyte PS exposure with normal platelet deposition in flow-restricted vessels.
Assessment of the Level of Abstractness of Material Statement of in Natural Sciences School Textbooks
Authors: Майер  , Mayer Robert 
Published: February 2017

The technique and results of an assessment of Abstractness of more than 20 modern school textbooks on biology, geography, physics and chemistry are
considered by method of pair comparisons. Thus it is assumed that didactic complexity of the textbook is mainly determined by the level of Abstractness
of the material stated in it and depends on: the variety and Abstractness of qualitative explanations, their isolation from everyday life (i); the complexity
of mathematical methods and models, variety of the solved quantitative problems (ii).
The levels of Abstractness of each textbook are determined, their distribution in two-dimensional space of attributes (i) and (ii) is studied. The received
results allow to range textbooks on their didactic complexity.
The Impact of Competition on “Make-or-Buy” Decisions: Evidence from the Spanish Local TV Industry
Authors: Gil Ricard , Ruzzier Christian A. 
Published: February 2017

This paper empirically investigates whether changes in product market competition affect firm boundaries. Exploiting regulation-induced shocks to entry barriers and differences in regulation enforcement across cities to obtain exogenous variation in competition, we establish a negative causal effect of competition (through reduced entry barriers and a larger number of rival firms) on vertical integration in the setting of the Spanish local television industry between 1995 and 2002. Data and the online appendix are available at https://doi.org/10.1287/mnsc.2016.2633 . This paper was accepted by Bruno Cassiman, business strategy.
Optimal Price and Delay Differentiation in Large-Scale Queueing Systems
Authors: Maglaras Costis , Yao John , Zeevi Assaf 
Published: February 2017

We study a multiserver queueing model of a revenue-maximizing firm providing a service to a market of heterogeneous price- and delay-sensitive customers with private individual preferences. The firm may offer a selection of service classes that are differentiated in prices and delays. Using a deterministic relaxation, which simplifies the problem by preserving the economic aspects of price-and-delay differentiation while ignoring queueing delays, we construct a solution to the fully stochastic problem that is incentive compatible and near optimal in systems with large capacity and market potential. Our approach provides several new insights for large-scale systems: (i) the deterministic analysis captures all pricing, differentiation, and delay characteristics of the stochastic solution that are nonnegligible at large scale; (ii) service differentiation is optimal when the less delay-sensitive market segment is sufficiently elastic; (iii) the use of “strategic delay” depends on system capacity and market heterogeneity—and it contributes significant delay when the system capacity is underutilized or when the firm offers three or more service classes; and (iv) connecting economic optimization to queueing theory, the revenue-optimized system has the premium class operating in a “quality-driven” regime and the lower-tier service classes operating with noticeable delays that arise either endogenously (“efficiency-driven” regime) or with the addition of strategic delay by the service provider. This paper was accepted by Gérard Cachon, stochastic models and simulation.
Social Desirability Bias in the 2016 Presidential Election
Authors: Klar Samara , Weber Christopher R. , Krupnikov Yanna 
Published: February 2017

AbstractPartisanship is a stable trait but expressions of partisan preferences can vary according to social context. When particular preferences become socially undesirable, some individuals refrain from expressing them in public, even in relatively anonymous settings such as surveys and polls. In this study, we rely on the psychological trait of self-monitoring to show that Americans who are more likely to adjust their behaviors to comply with social norms (i.e. high self-monitors) were less likely to express support for Donald Trump during the 2016 Presidential Election. In turn, as self-monitoring decreases, we find that the tendency to express support for Trump increases. This study suggests that – at least for some individuals – there may have been a tendency in 2016 to repress expressed support for Donald Trump in order to mask socially undesirable attitudes.
The Unexceptional Gender Gap of 2016
Authors: Burden Barry C. , Crawford Evan , DeCrescenzo Michael G. 
Published: February 2017

AbstractBecause of the particular candidates who ran, the 2016 presidential campaign was defined by gender to a remarkable degree. This led many observers to expect a historically large gender gap in voting. In contrast to these expectations, the gender gap between men and women’s votes in 2016 was only slightly larger than in other recent elections. We argue that an immense gender divide did not emerge because it was constrained by high levels of partisanship in the electorate, especially “negative partisanship” toward the opposing party that leaves little room for gender to matter. In addition, we challenge two common assumptions: that the gender gap helps Democratic candidates and that women were more persuadable than men over the course of the campaign. Both men and women vacillated in their views of Clinton’s honesty during the campaign, with men shifting away from her and toward Trump just before election day.
Development of Processing Maps for AZ81E Magnesium Alloy
Authors: Cao Han-xue , Wu Xue-yan , Liao Hui-min , Hao Meng-yao 
Published: February 2017

Abstract
The hot deformation characteristics of a AZ81E magnesium alloy are studied in the RANGE temperatures from 340 to 430 °C and strain rates ranging between 0.003 and 3.0 s−1 utilizing hot compression tests. Combining Arrhenius equation and Zener-Hollomon parameter, the high temperature flow stress model is proposed and the average activation energy is 166.15 kJ/mol. Processing maps for hot working are developed on the basis of the efficiency of power dissipation with changing temperatures and strain rates. The power dissipation map reveals that the optimum hot working domain is the temperature range of 390–400 °C and strain rate range of 0.03–0.3 s−1.