bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexe et genre dans les textes de la tradition juive
Authors: Chouraqui Jean-Marc 
Published: August 2017

Résumé
A partir du texte biblique et de ses commentaires talmudiques, midrachiques et cabalistiques, se déploie une problématique complexe aux multiples ramifications sur la question du rapport de l’Un à la dualité, à la différenciation/séparation en écho au concept de « sainteté » / « distinction », dont la transcendance serait le paradigme.
Le texte biblique repère un processus qui s’amorce avec un modèle androgyne (Adam) dans lequel s’entrelace l’Un et la dualité (masculine et féminine) jusqu’à une altérité radicale entre l’Homme et la Femme induisant une sexualité spécifique combinant, dans le droit, plaisir et procréation, et excluant de ce fait l’acte homosexuel. Une lecture cabalistique réaménage le rapport entre unité et dualité « En Haut », et s’interroge sur ce qu’il est advenu « En Bas ».
The Politics of Treaty Signature: The Role of Diplomats and Ties that Bind
Authors: Elsig Manfred , Karolina Milewicz 
Published: August 2017

AbstractThe literature on international cooperation through legal commitments focuses chiefly on treaty ratification. What has received much less attention is that before states ratify treaties, they commit to treaties through the act of signature. This article addresses this research gap by investigating how a state’s decision to sign a treaty is affected by its diplomatic representation during treaty negotiations. Conceptualizing signature as a commitment step, we argue that participation in treaty negotiations translates into a “ties-that-bind” effect creating incentives for diplomats to support the treaty text leading to treaty signature. Our empirical analysis uses a new data set on signature and tests the argument for 52 multilateral treaties concluded between 1990 and 2005. Results confirm that participation in treaty making matters for signature but not necessarily for ratification.
The Coherence of Public Reason
Authors: Lister Andrew 
Published: August 2017

Theories of public reason face a dilemma. If their standard of reasonableness is low, the view will be unacceptably anarchic and self-refuting, while if it is high, the exclusion of unreasonable views will manifest unequal treatment. This paper shows how to avoid this dilemma by distinguishing two models of public reason. The coercion model is vulnerable to the worry about anarchy but not self-defeat, while the reasons model is vulnerable to self-defeat but not anarchy. The coercion model can avoid anarchy without idealizing heavily via aggregation of individual policies into packages. The reasons model can avoid self-refutation by making acceptance of public reason one of the conditions for counting as fully reasonable, which is a natural constraint if the justification of the principle is relational.
Paintbrushes and Crowbars: Richard Rorty and the New Public-Private Divide
Authors: Anderson John P. 
Published: August 2017

In an often-quoted passage, Richard Rorty wrote that “J.S. Mill’s suggestion that governments devote themselves to optimizing the balance between leaving people’s lives alone and preventing suffering seems to me pretty much the last word.” In this article, I show why, for Rorty, maintaining a strong public-private divide that cordons off final vocabularies – the religious, racial, ethnic, sexual, gender, philosophical, and other terms so important for citizens’ private pursuits of self-creation and self-perfection – from public political discourse is a crucial means to accomplishing both of these goals in post-secular liberal democracies. Public political justifications should instead be articulated in the foundation-neutral terms of a shared national vocabulary. Like paintbrushes and crowbars, final and shared vocabularies are different tools for different purposes, and a strong public-private divide helps ensure that no harm comes from their misuse.
Examining the Climatology of Shortwave Radiation in the Northeastern United States
Authors: Hanrahan Janel , Maynard Alexandria , Murphy Sarah Y. , Zercher Colton , Fitzpatrick Allison 
Published: August 2017

AbstractAs demand for renewable energy grows, so does the need for an improved understanding of renewable energy sources. Paradoxically, the climate change mitigation strategy of fossil fuel divestment is in itself subject to shifts in weather patterns resulting from climate change. This is particularly true with solar power, which depends on local cloud cover. However, because observed shortwave radiation data usually span a decade or less, persistent long-term trends may not be identified. A simple linear regression model is created here using diurnal temperature range (DTR) during 2002–15 as a predictor variable to estimate long-term shortwave radiation (SR) values in the northeastern United States. Using an extended DTR dataset, SR values are computed for 1956–2015. Statistically significant decreases in shortwave radiation are identified that are dominated by changes during the summer months. Because this coincides with the season of greatest insolation and the highest potential for energy production, financial implications may be large for the solar energy industry if such trends persist into the future.
Evaluation of Multiple Planetary Boundary Layer Parameterization Schemes in Southeast U.S. Cold Season Severe Thunderstorm Environments
Authors: Cohen Ariel E. , Cavallo Steven M. , Coniglio Michael C. , Brooks Harold E. , Jirak Israel L. 
Published: August 2017

Abstract
Southeast U.S. cold season severe weather events can be difficult to predict because of the marginality of the supporting thermodynamic instability in this regime. The sensitivity of this environment to prognoses of instability encourages additional research on ways in which mesoscale models represent turbulent processes within the lower atmosphere that directly influence thermodynamic profiles and forecasts of instability. This work summarizes characteristics of the southeast U.S. cold season severe weather environment and planetary boundary layer (PBL) parameterization schemes used in mesoscale modeling and proceeds with a focused investigation of the performance of nine different representations of the PBL in this environment by comparing simulated thermodynamic and kinematic profiles to observationally influenced ones. It is demonstrated that simultaneous representation of both nonlocal and local mixing in the Asymmetric Convective Model, version 2 (ACM2), scheme has the lowest overall errors for the southeast U.S. cold season tornado regime. For storm-relative helicity, strictly nonlocal schemes provide the largest overall differences from observationally influenced datasets (underforecast). Meanwhile, strictly local schemes yield the most extreme differences from these observationally influenced datasets (underforecast) in a mean sense for the low-level lapse rate and depth of the PBL, on average. A hybrid local–nonlocal scheme is found to mitigate these mean difference extremes. These findings are traced to a tendency for local schemes to incompletely mix the PBL while nonlocal schemes overmix the PBL, whereas the hybrid schemes represent more intermediate mixing in a regime where vertical shear enhances mixing and limited instability suppresses mixing.
Does Snoring Time Always Reflect the Severity of Obstructive Sleep Apnea?
Authors: Hong Seung-No , Yoo Jun , Song In Sik , Joo Jae Woo , Yoo June Hyuk , Kim Tae Hoon , Lee Heung Man , Lee Sang Hag , Lee Seung Hoon 
Published: August 2017

Objectives: Although it is commonly believed that the degree of snoring reflects the severity of obstructive sleep apnea (OSA), there is often a mismatch between the improvement in OSA and the decrease of snoring time following OSA treatment. The aim of this study was to determine the relationship between OSA severity and snoring time. Methods: A total of 280 subjects who complained of snoring were divided by apnea-hypopnea index (AHI) into 5 groups. The snoring rate (the amount of sleep time spent snoring divided by the total sleep time) and the clinical data including polysomnographic findings were compared and analyzed. Results: There was no significant correlation between AHI and snoring rate (r = −0.038, P = .524). The snoring rate in the control group was significantly lower than that in the moderate ( P < .001) and severe ( P = .003) groups. The snoring rate in the very severe group was significantly lower than those in the mild ( P < .001), moderate ( P < .001), and severe ( P < .001) groups. However, there was no significant difference between snoring rates in the control group and the very severe group ( P = .832). Conclusions: The change in snoring rate according to the severity of AHI showed an inverted U-shaped pattern, with a peak in the moderate OSA group.
Impact of the economic crisis on health-related behaviors in Italy
Authors: Mattei Giorgio , De Vogli Roberto , Ferrari Silvia , Pingani Luca , Rigatelli Marco , Galeazzi Gian Maria 
Published: August 2017

Background: Evidence exists supporting the impact of the Great Recession on health-related behaviors internationally, though few studies are available concerning the Italian population. Aim: To assess the impact of the late 2000s economic crisis on health-related behaviors linked to population mental health in Italy. Methods: Descriptive study. Health indicators came from the Italian Institute of Statistics database (years 2000–2015). Statistics performed by means of linear regression models. Results: Increased smokers (β = 1.68, p = .03), heavy smokers, that is, people smoking 11–20 cigarettes per day (β = 2.18, p = .04) or more than 20 cigarettes per day (β = 1.04, p < .01) and mean number of smoked cigarettes per day (β = 0.56, p = .02) were noticeable. Also, prevalence of overweight increased (β = 0.91, p = .04), while the Italian families’ expenditure for alcoholic beverages decreased (β = –812.80, p = .01). Alcohol consumption decreased (β = –0.60, p < .01), especially in men (β = –0.95, p < .01); binge drinking increased in years 2009–2010. No change was noticeable in the diet indicators collected. Conclusion: The economic crisis may have increased smoking, overweight and binge drinking in Italy (though data on the latter phenomenon are not conclusive), and reduced overall alcohol consumption.
Left atrial volume index in patients with heart failure and severely impaired left ventricular systolic function: the role of established echocardiographic parameters, circulating cystatin C and galectin-3
Authors: Zivlas Christos , Triposkiadis Filippos , Psarras Stelios , Giamouzis Gregory , Skoularigis Ioannis , Chryssanthopoulos Stavros , Kapelouzou Alkistis , Ramcharitar Steve , Barnes Edward , Papasteriadis Evangelos , Cokkinos Dennis 
Published: August 2017

Backround: Left atrial (LA) enlargement plays an important role in the development of heart failure (HF) and is a robust prognostic factor. Fibrotic processes have also been advocated to evoke HF through finite signalling proteins. Methods: We examined the association of two such proteins, cystatin C (CysC) and galectin-3 (Gal-3), and other clinical, echocardiographic and biochemical parameters with LA volume index (LAVi) in patients with HF with severely impaired left ventricular ejection fraction (LVEF). Severe renal, liver, autoimmune disease and cancer were exclusion criteria. Results: A total of 40 patients with HF (31 men, age 66.6 ± 1.7) with LVEF = 25.4 ± 0.9% were divided into two groups according to the mean LAVi (51.03 ± 2.9 ml/m2) calculated by two-dimensional transthoracic echocardiography. Greater LAVi was positively associated with LV end-diastolic volume ( p = 0.017), LV end-systolic volume ( p = 0.025), mitral regurgitant volume (MRV) ( p = 0.001), right ventricular systolic pressure (RVSP) ( p < 0.001), restrictive diastolic filling pattern ( p = 0.003) and atrial fibrillation ( p = 0.005). Plasma CysC was positively correlated with LAVi ( R2 = 0.135, p = 0.019) and log-transformed plasma Gal-3 ( R2 = 0.109, p = 0.042) by simple linear regression analysis. Stepwise multiple linear regression analysis showed that only MRV ( t = 2.236, p = 0.032), CysC ( t = 2.467, p = 0.019) and RVSP ( t = 2.155, p = 0.038) were significant predictors of LAVi. Conclusions: Apart from known determinants of LAVi, circulating CysC and Gal-3 were associated with greater LA dilatation in patients with HF with reduced LVEF. Interestingly, the correlation between these two fibrotic proteins was positive.
Private Rooms in Low Acuity Settings: A Systematic Review of the Literature
Authors: Voigt Jeffrey , Mosier Michael , Darouiche Rabih 
Published: August 2017

Objectives: Determine if the peer-reviewed evidence supports single-patient ward bedrooms in low-acuity care settings within a hospital. Background: New evidence exists since the 2006 Facility Guideline Institute guideline recommended single-bedded rooms (SBRs) in low-acuity care settings. Additionally, prior studies evaluated high-acuity care settings (e.g., critical care) in their recommendations on SBRs. There is a need to reevaluate the evidence. Methods: A systematic review of the literature was completed including electronic and hand searches of references. A data extraction form was utilized. Two reviewers evaluated the studies independently. Studies that were included examined the effect of single-patient rooms on medical surgical ward beds only. Each study was graded using accepted clinical evidence grading instruments. Results: Over 1,400 records were identified. After excluding studies, a total of 49 records were graded. The highest quality evidence identified (Center for Evidence-Based Medicine [CEBM]: 2a, 2b, and Grading of Recommendations, Assessment, Development, and Evaluation [GRADE] C) did not support the use of single-patient rooms for reducing infections, for minimizing patient falls, for reducing medication errors, or for patient satisfaction. Operational efficiencies were improved with SBRs but only addressed the maternity ward. The lowest quality evidence (CEBM: 4/5 and GRADE D) supported the use of single-patient rooms. Conclusions: Based on CEBM and GRADE assessments, there is a lack of high-quality data supporting the use of low-acuity SBRs throughout the entire hospital. Furthermore, it is recommended that more research be conducted on the effect of SBRs, so higher quality evidence is developed.
The impact of medial cuneiform bone variant measures on the severity of hallux valgus: A radiological study
Authors: Erduran Mehmet , Acar Nihat , Demirkiran Nihat D , Atalay Kaan 
Published: August 2017

Purpose: The aetiology of hallux valgus (HV) is multifactorial in nature. The first metatarsocuneiform joint obliquity is a well-known factor in the development of the deformity. The purpose of this study is to assess the correlation of different medial cuneiform radiological measures on the severity of HV. Methods: Full weight-bearing anteroposterior views of 152 feet with different clinical severity are divided into four groups: without deformity and with mild, moderate and severe deformities. Three medial cuneiform angles were assessed, namely, the first metatarsocuneiform angle (MCA), the first metatarsocuneiform slope angle (MCSA) and the medial cuneiform lateral tilt angle (MCLTA). Results: The first MCA average values of groups 1, 2, 3 and 4 were (25.16 ± 5.74°, 27.38 ± 6.14°, 30.27 ± 5.62° and 34.28 ± 6.81°), respectively. Statistical differences were detected between groups (1, 3) and (1, 4) with p values of 0.034 and 0.001, respectively. The average values of the first MCSA of groups 1, 2, 3 and 4 were 19.26 ± 4.97°, 22.54 ± 5.62°, 26.13 ± 6.36° and 32.17 ± 5.85°, respectively. Significant differences were detected between groups (1, 3) and (1, 4) with p values of 0.04 and 0.023, respectively. Average values of the MCLTA of groups 1, 2, 3 and 4 were 80.85 ± 4.49°, 74.56 ± 5.28°, 62.38 ± 6.34° and 58.78 ± 6.25°, respectively. Statistical significances were detected between groups (1, 2), (1, 3) and (1, 4) with p values of 0.026, 0.018 and 0.001, respectively. Conclusions: Increasing the medial cuneiform lateral tilt increases the first metatarsocuneiform articulation obliquity demonstrated by the increase in the first MCSA which in term enhances the progression of varus deformity of the first metatarsal bone explained by the increase in the first MCA.
The Effects of Medical Well Baby Visits in Promoting Earlier First Dental Visits for Children
Authors: Park S. , Momany E.T. , Jones M.P. , Kuthy R.A. , Askelson N.M. , Wehby G.L. , Damiano P.C. , Chi D.L. 
Published: August 2017

The objective of the study was to assess the effects of medical well baby visits in promoting earlier first dental visits. We analyzed Iowa Medicaid claims data (2000–2013). The sample included 4 cohorts of children born in 2000, 2003, 2007, or 2010 and enrolled in Medicaid from birth ( N = 38,211). Children were followed for 3 y. The independent variables were cohort year and medical well baby visit frequency during 3 time periods (birth to age 10 mo, ages 11–19 mo, ages 20–36 mo). We used survival analyses to estimate first dental visit rates. First dental visit rates improved significantly from 2000 to 2013, with children in latter cohorts having significantly earlier first dental visits. Children with more medical well baby visits before age 11 mo had significantly delayed first dental visit rates than children with fewer medical well baby visits. The opposite was observed for children with more medical well baby visits between ages 11 to 19 mo and ages 20 to 36 mo. First dental visit rates for Medicaid-enrolled children have improved, but there continues to be a need for early interventions to improve age 1 dental visits and other preventive oral health behaviors. Knowledge Transfer Statement: The results of this study can be used by policy makers when developing strategies to improve access to dental care for young children in Medicaid. With consideration to promoting earlier preventive dental visits for publicly insured children, this study could lead to early interventions and improved health outcomes.
Funduscopic and Angiographic Characteristics in Early and Late Macular Telangiectasia Type 2
Authors: Jaisankar Durgasri , Gondhale Harshal , Chhablani Jay , Agarwal Manisha , Raman Rajiv 
Published: August 2017

Purpose: To report the morphological and vascular characteristics using funduscopic and angiographic features in different cohort as stratified by stages of macular telangiectasia type 2 (MacTel 2). Methods: A cross-sectional, multicentered study of 149 eyes (75 patients) with MacTel 2 was done. The eyes were divided into 2 groups: early group which includes eyes with stages 1 (40 eyes), 2 (41 eyes), and 3 (32 eyes) of MacTel 2 and late group which includes eyes with stages 4 (13 eyes) and 5 (23 eyes) of MacTel 2. The morphological and vascular characteristics on fundus examination and fluorescein angiography (FA) were studied in both groups and their association was found. Results: The gender (female: odds ratio [OR] = 4.98, P = .040), presence of dilated parafoveal capillaries (OR = 2.668, P = .026), retinal pigment plaques (OR = 27.067, P = .0001), patchy choroidal filling in FA (OR = 3.536, P = .004), and presence of prominent arteriole (OR = 3.434, P = .002) were associated with late stages of MacTel 2. Conclusion: Presence of retinal pigment plaques, dilated parafoveal capillaries, patchy choroidal filling, and female gender are more likely to be associated with late-stage disease.
Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia
Authors: Dovey Oliver M. , Cooper Jonathan L. , Mupo Annalisa , Grove Carolyn S. , Lynn Claire , Conte Nathalie , Andrews Robert M. , Pacharne Suruchi , Tzelepis Konstantinos , Vijayabaskar M. S. , Green Paul , Rad Roland , Arends Mark , Wright Penny , Yusa Kosuke , Bradley Allan , Varela Ignacio , Vassiliou George S. 
Published: August 2017

Key Points
Npm1c and Nras-G12D co-mutation in mice leads to AML with a longer latency and a more mature phenotype than the Npm1c/Flt3-ITD combination. Mutant Flt3 or Nras allele amplification is the dominant mode of progression in both Npm1c/Flt3-ITD and Npm1c/Nras-G12D murine AML.
CLEC-2 contributes to hemostasis independently of classical hemITAM signaling in mice
Authors: Haining Elizabeth J. , Cherpokova Deya , Wolf Karen , Becker Isabelle C. , Beck Sarah , Eble Johannes A. , Stegner David , Watson Steve P. , Nieswandt Bernhard 
Published: August 2017

Key Points
An inactivating point mutation in the hemITAM motif of murine CLEC-2 reproduces the lymphatic defects seen in CLEC-2–deficient mice. CLEC-2 contributes to thrombus stability in vivo independently of hemITAM signaling.
Pharmacotherapeutical strategies in the prevention of acute, vaso-occlusive pain in sickle cell disease: a systematic review
Authors: Sins Joep W. R. , Mager David J. , Davis Shyrin C. A. T. , Biemond Bart J. , Fijnvandraat Karin 
Published: August 2017

AbstractSickle-cell disease (SCD) is characterized by frequent and painful vaso-occlusive crises (VOCs). Various treatments have been evaluated over the years. However, a clear overview is lacking. The objective of this study was to systematically review all pharmacotherapeutical strategies in the prevention of VOCs beyond hydroxyurea. We performed a systematic literature search (MEDLINE, Embase, CENTRAL). Eligible studies were controlled clinical trials evaluating pharmacotherapeutical interventions targeting the reduction of VOCs in patients with SCD. Primary outcomes were the number or duration of SCD-related pain days, VOCs, or hospital admissions for VOCs. Secondary outcomes included time to first VOC or hospital admission for a VOC. A standardized data extraction sheet was used. The methodological quality of studies was assessed using Cochrane’s risk-of-bias tool. A total of 36 studies were included in this review, covering 26 different prophylactic interventions. The most promising interventions for reducing the frequency of either VOCs or hospitalizations were the oral antioxidants l-glutamine and ω-3 fatty acids and the IV antiadhesive agent crizanlizumab. Twenty-three studies did not show any beneficial effect of the intervention under investigation, and 6 studies were either too small or methodologically inadequate to draw conclusions. Because of the heterogeneity of interventions, no meta-analysis was performed. In conclusion, this review identified 3 promising pharmacotherapeutical strategies in the prevention of VOCs in SCD. Importantly, this study highlights the discrepancy between the significant burden of SCD worldwide and the low number of adequate trials performed. This review was registered at PROSPERO (CRD42015025250).