bluuebunny/crossref_metadata_2025_split huggingface dataset:
PAISAGEM E TURISTIFICAÇÃO: ESTUDO DE CASO EM CANOA QUEBRADA E MAJORLÂNDIA, CE, BRASIL.
Authors: Souza Roberto Sakamoto Rezende de 
Published: November 2015

O presente artigo tem como proposta uma análise do processo de turistificação e suas implicações na transformação da paisagem de localidades turísticas litorâneas no Brasil, através de um estudo de caso na região do município de Aracati, no Ceará. Peguntamo-nos inicialmente qual o motivo de Canoa Quebrada ser o destino turístico mais estruturado, e, portanto, preferido pelos turistas que procuram a região. Propõe-se como ponto de partida para a pesquisa a investigação do discurso das fontes oficiais de informação sobre o processo de desenvolvimento turístico da região e o seu confrontamento com observações realizadas em visita de campo.PALAVRAS-CHAVE: Paisagem. Turistificação. Canoa Quebrada. LANDSCAPE AND TOURISTIFICATION: CASE STUDY IN CANOA QUEBRADA AND MAJORLÂNDIA,CE, BRASIL. ABSTRACT: This article presents an analysis of the touristification's process and its implications on the transformation of touristic locations on the Brazilian coast, through a case study that took place in Aracari, located in the state of Ceará. Initially, we wondered what was the reason that made Canoa Quebrada be the most structured touristic destination and, therefore, becoming the tourists' favorite destination in the region. It was proposed as a starting point for research the investigation of information official sources' speeches on the touristic development process in the region and its confrontation with observation during site visits. PAISAJE Y TURISTIFICACIÓN: ESTUDIO DE CASO EN CANOA QUEBRADA Y MAJORLÂNDIA, CE, BRASIL. RESUMEN: El presente artículo tiene como propuesta un análisis del proceso de “turistificación” y sus implicaciones en la transformación del paisaje de asentamientos turísticos costeros en Brasil, a través de un estudio de caso en la región del municipio de Aracati, en el Estado de Ceará. Inicialmente nos preguntamos cual es la razón de por qué Canoa Quebrada se configura como el destino turístico más consolidado en cuanto a infraestructura y servicios y, por lo tanto, preferido por los turistas que buscan la región. Se propone como punto de partida para la investigación el desarrollo de un marco teórico conformado por diversas fuentes oficiales de información sobre el proceso de desarrollo turístico de la región y su confrontación con observaciones realizadas en visita a terreno.
O CORREDOR TRANSFRONTEIRIÇO: INTERAÇÃO E INTEGRAÇÃO ENTRE O AMAPÁ E A GUIANA FRANCESA
Authors: Tostes José Alberto , Ferreira José Francisco Carvalho 
Published: November 2015

Os territórios transfronteiriços se constituem, em simultâneo, espaços de características multifacetadas, natureza diversa e ambientes complexos e espaços de contato e articulação, de encontro e cooperação. Tratados, por muito tempo, como lugares periféricos, eles assumem-se, hoje, como espaços estratégicos. É neste contexto que este artigo propõe o Corredor Transfronteiriço como uma base reflexiva para compreender a interação e integração do Amapá (Brasil) com a Guiana Francesa (França), dois territórios de fronteira. O objetivo principal deste artigo é definir e apresentar o conceito de Corredor Transfronteiriço, oferendo uma possibilidade de entendimento e fortalecimento das relações sócio-políticas, ambientais e econômicas destes territórios, em todas as suas percepções. Palavras-Chave: Corredor Transfronteiriço; integração; territórios de Fronteira; Amapá; Guiana Francesa. TRANSBOUNDARY CORRIDOR: INTERACTION AND INTEGRATION BETWEEN AMAPÁ AND FRENCH GUYANA ABSTRACTCross-border territories are, simultaneously, multi-faceted, diverse and complex environments spaces and contact and articulation, holding and cooperation spaces. Treated, for a long time, as peripheral places, they take up today as strategic ones. In this context, this article proposes the Transboundary Corridor as a reflexive basis for understanding the interaction and integration of Amapá (Brazil) with French Guyana (France), two border territories. The main purpose of this article is to define and introduce the concept of Transboundary Corridor, offering a possibility of understanding and strengthening the socio-political, environmental and economic relations of these two territories, in all its perceptions. Keywords: Transboundary Corridor; integration; border territories; Amapá; French Guyana EL CORREDOR TRANSFRONTEIRIZO: INTERACCIÓN E INTEGRACIÓN ENTRE O AMAPÁ E A GUYANA FRANCESA RESUMENLos Territorios transfronterizos son al mismo tiempo espacios de múltiples facetas, de naturaleza diversa y entornos complejos y espacios de contacto y reunión conjunta y cooperación. Tratada, largo tiempo, como lugares periféricos, son, hoy en día, espacios estratégicos. En este contexto, el presente artículo se propone el Corredor Fronterizo como base reflexiva para la comprensión de la interacción e integración de Amapá (Brasil) con la Guayana Francesa (Francia), dos territorios fronterizos. El propósito principal de este artículo es definir e introducir el concepto de Corredor Transfronterizo, que ofrece una posibilidad de entendimiento y fortalecimiento de las relaciones socio-políticas, ambientales y económicas de estos territorios y su potencial, en todas sus percepciones. Palabras clave: Corredor Transfronterizo; integración; territorios fronterizos; Amapá; Guyana Francesa.
ÁGUA E SANEAMENTO: A MÍDIA VERSUS OS DADOS
Authors: Medeiros Herika Bastos de , Souza Luis Gabriel Rodrigues , Araújo Maria Socorro da Silva 
Published: November 2015

O objetivo desse trabalho é discutir o impacto ambiental e os efeitos dos poluentes ao meio ambientes. Ao mesmo tempo em que os dados de contaminação são divulgados, os governos, em contrapartida, apresentam na mídia planos para o futuro que não são cumpridos. Nesse sentido se faz imprescindível uma gestão ambiental comprometida com a sociedade, visando investimentos que realmente consigam apresentar retorno de melhoria de qualidade das águas. PALAVRAS-CHAVE: Amazônia, Doenças de veiculação hídrica. Saneamento. AGUA Y SANEAMIENTO: LOS MEDIOS DE COMUNICACIÓN FRENTE A LOS DATOS RESUMENEl objetivo de este trabajo es discutir el impacto ambiental y los efectos de los contaminantes para el medio ambiente. Al mismo tiempo que se comuniquen los datos de contaminación, los gobiernos, en cambio, característica en los medios de comunicación los planes para el futuro que no se cumplen. En este sentido si hace imprescindible gestión ambiental comprometida con la sociedad, con el objetivo de las inversiones que realmente pueden presentar retorno de mejora de la calidad del agua. PALABRAS CLAVE: Amazonas, enfermedades transmitidas por el agua. Saneamiento. WATER AND SANITATION: THE MEDIA VERSUS THE DATA SUMMARYThe objective of this work is to discuss the environmental impact and the effects of pollutants to the environment. At the same time that the contamination data are disclosed, Governments, in contrast, feature in the media plans for the future that are not met. In this sense if it makes essential environmental management committed to society, aiming at investments that really can submit return of water-quality improvement. KEYWORDS: Amazon, waterborne diseases. Sanitation.
DESENVOLVIMENTO ARQUITETÔNICO DE JOÃO PESSOA ENTRE 1980 E 1990
Authors: Martins Rayssa Raphaely Souza 
Published: November 2015

Este artigo aborda o desenvolvimento arquitetônico de João Pessoa – Paraíba entre os anos 1985 e 1994, a fim de identificar a repercussão da produção arquitetônica pós-moderna na capital pessoense e suas transformações na paisagem da cidade, através dos exemplares realizados na cidade e identificados através do referencial teórico. PALAVRAS-CHAVE: Desenvolvimento arquitetônico; Pós-moderno; João Pessoa. ARCHITECTURAL DEVELOPMENT OF JOÃO PESSOA BETWEEN 1980 AND 1990 ABSTRACTThis article discusses the architectural development of João Pessoa - Paraíba between the years 1985 and 1994 in order to identify the impact of postmodern architectural production in pessoense capital and its transformations in the landscape of the city, through the copies held in the city and identified by the theoretical framework. KEYWORDS : Architectural Development; Postmodern; João Pessoa. EL DESARROLLO ARQUITECTÓNICO DE JOÃO PESSOA ENTRE 1980 Y 1990 RESUMENEste artículo aborda el desarrollo arquitectónico de João Pessoa - Paraíba entre los años 1985 y 1994 con el fin de identificar el impacto de la producción arquitectónica posmoderna en la capital pessoense y sus transformaciones en el paisaje de la ciudad, a través de las copias realizadas en la ciudad y identificadas por el marco teórico. PALABRAS CLAVE: Desarrollo Arquitectónico; Posmoderno; João Pessoa.
PSYCHOLOGICAL FACTORS IN SHAPING INVESTOR EXPECTATION ON CAPITAL MARKETS
Authors: Mikołajek-Gocejna Magdalena 
Published: November 2015

Investor expectations about the course of future economic processes are one of the key factors influencing their decisions. It seems that expectations play a particular role because they constitute unobservable variables that can account for observable economic phenomena. Getting to know the process of how investor expectations are formed is a crucial element of description, interpretation and forecasting changes in the value of assets on financial markets, and especially changes in stock prices on capital markets which affect the value of publicly traded companies. The aim of this paper is to present the psychological factors shaping investor expectations and influencing the market value of companies, factors determining both the motivational and cognitive inclinations of investors. The main questions that arise from the background of the analysis conducted in this paper are: 1. whether awareness of the psychological determinants of investment decisions enables companies to consciously create long-term investor expectations, inspiring, in a sense, a more fundamental response from the capital market, 2. whether there is the potential to include investor expectations in the value-‑based management process and to make the transition from value-based management to expectations-based management.
THE APPLICATION OF BEHAVIOURAL FINANCE TO ENHANCE VOLUNTARY RETIREMENT SAVINGS – ARE THE SOLUTIONS UNIVERSAL AROUND THE WORLD?
Authors: Sieczkowski WOJCIECH 
Published: November 2015

Behavioural finance is a promising solution to enhance voluntary retirement savings (VRS) and is gaining recognition around the world. Despite this, there may be some limitations to the transferability of its applications. This paper summarizes the key findings relevant to long-term savings and then analyses these aforementioned limitations, by first pointing to some methodological assumptions made, and then looking at the potential set of variables impacting the applications’ transferability.
Histological studies of cellular differentiation during somatic embryogenesis of coconut plumule-derived calli
Authors: Jayaraj K. Lakshmi , Bhavyashree U. , Fayas T.P. , Sajini K.K. , Rajesh M.K. , Karun Anitha 
Published: November 2015

<div><table cellspacing="0" cellpadding="0" align="center"><tbody><tr><td align="left" valign="top"><p>Since coconut is one of the most recalcitrant species to generate <em>in vitro</em>, it is necessary to study in detail about the cellular changes that occur during somatic embryogenesis to enhance our knowledge about this phenomenon. In the present study, coconut plumular tissues, the shoot meristem including leaf primordia, were used as explants for <em>in vitro </em>regeneration studies. Histological studies were carried out in different stages of plumule culture. No noticeable growth was observed in 15 days old cultures. After 30 days, meristematic cells could be identified. Abundance of meristematic cells, foremost to the development of callus structures, was observed after 45 days. After 75 days, globular friable calli were formed and histological studies revealed the presence of meristematic centers which eventually formed somatic embryos. The histological study of matured somatic embryos formed after 120 days of callus initiation showed a clear meristematic zone of parenchyma cells, surrounded by vascular bundles. Histological studies, carried out for certain abnormalities like compact calli, abnormal somatic embryoids with rudimentary shoots and multiplied roots, revealed the presence of intact cotyledonary leaves which seemed to inhibit the apical meristem development of somatic embryoids. The presence of vascular bundles in the early stages of callus formation might lead to the direct formation of meristemoids. These results could aid future studies leading to enhanced control of the somatic embryogenic process and greater efficiency of somatic embryo and plantlet formation in coconut.</p></td></tr></tbody></table></div>
Surgical anatomy and utility of pedicled vascularized tissue flaps for multilayered repair of skull base defects
Authors: Safavi-Abbasi Sam , Komune Noritaka , Archer Jacob B. , Sun Hai , Theodore Nicholas , James Jeffrey , Little Andrew S. , Nakaji Peter , Sughrue Michael E. , Rhoton Albert L. , Spetzler Robert F. 
Published: November 2015

OBJECT
The objective of this study was to describe the surgical anatomy and technical nuances of various vascularized tissue flaps.

METHODS
The surgical anatomy of various tissue flaps and their vascular pedicles was studied in 5 colored silicone-injected anatomical specimens. Medical records were reviewed of 11 consecutive patients who underwent repair of extensive skull base defects with a combination of various vascularized flaps.

RESULTS
The supraorbital, supratrochlear, superficial temporal, greater auricular, and occipital arteries contribute to the vascular supply of the pericranium. The pericranial flap can be designed based on an axial blood supply. Laterally, various flaps are supplied by the deep or superficial temporal arteries. The nasoseptal flap is a vascular pedicled flap based on the nasoseptal artery. Patients with extensive skull base defects can undergo effective repair with dual flaps or triple flaps using these pedicled vascularized flaps.

CONCLUSIONS
Multiple pedicled flaps are available for reconstitution of the skull base. Knowledge of the surgical anatomy of these flaps is crucial for the skull base surgeon. These vascularized tissue flaps can be used effectively as single or combination flaps. Multilayered closure of cranial base defects with vascularized tissue can be used safely and may lead to excellent repair outcomes.
Intracranial application of near-infrared light in a hemi-parkinsonian rat model: the impact on behavior and cell survival
Authors: Reinhart Florian , Massri Nabil El , Chabrol Claude , Cretallaz Celine , Johnstone Daniel M. , Torres Napoleon , Darlot Fannie , Costecalde Thomas , Stone Jonathan , Mitrofanis John , Benabid Alim-Louis , Moro Cécile 
Published: November 2015

OBJECT
The authors of this study used a newly developed intracranial optical fiber device to deliver near-infrared light (NIr) to the midbrain of 6-hydroxydopamine (6-OHDA)-lesioned rats, a model of Parkinson’s disease. The authors explored whether NIr had any impact on apomorphine-induced turning behavior and whether it was neuroprotective.

METHODS
Two NIr powers (333 nW and 0.16 mW), modes of delivery (pulse and continuous), and total doses (634 mJ and 304 J) were tested, together with the feasibility of a midbrain implant site, one considered for later use in primates. Following a striatal 6-OHDA injection, the NIr optical fiber device was implanted surgically into the midline midbrain area of Wistar rats. Animals were tested for apomorphine-induced rotations, and then, 23 days later, their brains were aldehyde fixed for routine immunohistochemical analysis.

RESULTS
The results showed that there was no evidence of tissue toxicity by NIr in the midbrain. After 6-OHDA lesion, regardless of mode of delivery or total dose, NIr reduced apomorphine-induced rotations at the stronger, but not at the weaker, power. The authors found that neuroprotection, as assessed by tyrosine hydroxylase expression in midbrain dopaminergic cells, could account for some, but not all, of the observed behavioral improvements; the groups that were associated with fewer rotations did not all necessarily have a greater number of surviving cells. There may have been other “symptomatic” elements contributing to behavioral improvements in these rats.

CONCLUSIONS
In summary, when delivered at the appropriate power, delivery mode, and dosage, NIr treatment provided both improved behavior and neuroprotection in 6-OHDA-lesioned rats.
Magnetic resonance imaging artifact following anterior cervical discectomy and fusion with a trabecular metal cage
Authors: Elliott Cameron A. , Fox Richard , Ashforth Robert , Gourishankar Sita , Nataraj Andrew 
Published: November 2015

OBJECT
This study was undertaken to evaluate the impact of postoperative MRI artifact on the assessment of ongoing spinal cord or nerve root compression after anterior cervical discectomy and fusion (ACDF) using a trabecular tantalum cage or bone autograft or allograft.

METHODS
The authors conducted a retrospective review of postoperative MRI studies of patients treated surgically for cervical disc degenerative disease or cervical instability secondary to trauma. Standard ACDF with either a trabecular tantalum cage or interbody bone graft had been performed. Postoperative MR images were shown twice in random order to each of 3 assessors (2 spine surgeons, 1 neuroradiologist) to determine whether the presence of a tantalum interbody cage and/or anterior cervical fixation plate or screws imparted MRI artifact significant enough to prevent reliable postoperative assessment of ongoing spinal cord or nerve root compression.

RESULTS
A total of 63 patients were identified. One group of 29 patients received a tantalum interbody cage, with 13 patients (45%) undergoing anterior plate fixation. A second group of 34 patients received bone auto- or allograft, with 23 (68%) undergoing anterior plate fixation. The paramagnetic implant construct artifact had minimal impact on visualization of postoperative surgical level spinal cord compression. In the cage group, 98% (171/174) of the cases were rated as assessable versus 99% in the bone graft group (201/204), with high intraobserver reliability. In contrast, for the assessment of ongoing surgical level nerve root compression, the presence of a tantalum cage significantly decreased visualization of nerve roots to 70% (121/174) in comparison with 85% (173/204) in the bone graft group (p < 0.001). When sequences using turbo spin echo (TSE), a T2-weighted axial sequence, were acquired, nerve roots were rated as assessable in 88% (69/78) of cases; when only axial T2-weighted sequences were available, the nerve roots were rated as assessable in 54% (52/96) of cases (p < 0.01). The presence of anterior plate fixation had minimal impact on visualization of the spinal cord (99% [213/216] for plated cases vs 98% [159/162] for nonplated cases; p = 1.0) or nerve roots (79% [170/216] for plated cases vs 77% [124/162] for nonplated cases; p = 0.62).

CONCLUSIONS
Interbody fusion with tantalum cage following anterior cervical discectomy imparts significant paramagnetic artifact, which significantly decreases visualization and assessment of ongoing surgical level nerve root, but not spinal cord, compression. Anterior plate constructs do not affect visualization of these structures. TSE T2-weighted sequences significantly improve nerve root visualization and should be performed as part of a standard postoperative protocol when imaging the cervical spine following interbody implantation of materials with potential for paramagnetic artifact.
Neuron-derived orphan receptor 1 transduces survival signals in neuronal cells in response to hypoxia-induced apoptotic insults
Authors: Chio Chung-Ching , Wei Li , Chen Tyng Guey , Lin Chien-Min , Shieh Ja-Ping , Yeh Poh-Shiow , Chen Ruei-Ming 
Published: November 2015

OBJECT
Hypoxia can induce cell death or trigger adaptive mechanisms to guarantee cell survival. Neuron-derived orphan receptor 1 (NOR-1) works as an early-response protein in response to a variety of environmental stresses. In this study, the authors evaluated the roles of NOR-1 in hypoxia-induced neuronal insults.

METHODS
Neuro-2a cells were exposed to oxygen/glucose deprivation (OGD). Cell viability, cell morphology, cas-pase-3 activity, DNA fragmentation, and cell apoptosis were assayed to determine the mechanisms of OGD-induced neuronal insults. RNA and protein analyses were carried out to evaluate the effects of OGD on expressions of NOR-1, cAMP response element-binding (CREB), and cellular inhibitor of apoptosis protein 2 (cIAP2) genes. Translations of these gene expressions were knocked down using RNA interference. Mice subjected to traumatic brain injury (TBI) and NOR-1 was immunodetected.

RESULTS
Exposure of neuro-2a cells to OGD decreased cell viability in a time-dependent manner. Additionally, OGD led to cell shrinkage, DNA fragmentation, and cell apoptosis. In parallel, treatment of neuro-2a cells with OGD time dependently increased cellular NOR-1 mRNA and protein expressions. Interestingly, administration of TBI also augmented NOR-1 levels in the impacted regions of mice. As to the mechanism, exposure to OGD increased nuclear levels of the transcription factor CREB protein. Downregulating CREB expression using RNA interference simultaneously inhibited OGD-induced NOR-1 mRNA expression. Also, levels of cIAP2 mRNA and protein in neuro-2a cells were augmented by OGD. After reducing cIAP2 translation, OGD-induced cell death was reduced. Sequentially, application of NOR-1 small interfering RNA to neuro-2a cells significantly inhibited OGD-induced cIAP2 mRNA expression and concurrently alleviated hypoxia-induced alterations in cell viability, caspase-3 activation, DNA damage, and cell apoptosis.

CONCLUSIONS
This study shows that NOR-1 can transduce survival signals in neuronal cells responsible for hypoxiainduced apoptotic insults through activation of a CREB/cIAP2-dependent mechanism.