bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of clinical pharmacy services within the primary care–mental health integration model at the Tuscaloosa Veterans Affairs Medical Center
Authors: Parikh Mamta , Ebong Ekaette E. , Harris Erin , Barnes Brittany 
Published: August 2016

Abstract
Introduction: The purpose of this review is to evaluate the direct delivery of health care to veterans before and after incorporating clinical pharmacy services within primary care mental health integration (PCMHI) at the Tuscaloosa Veterans Affairs Medical Center. Prior to establishing the role of the clinical pharmacy specialist (CPS) within PCMHI, the primary care providers deferred all mental health assessments to specialty mental health. As the demands of the service grew exponentially, assistance from clinical pharmacy was critical.
Methods: A randomized, computer-generated list of 114 patients selected for the retrospective chart review was used to evaluate clinical outcomes in patients enrolled in the PCMHI clinic 1 year preincorporation and postincorporation of CPS. Outcome measures included the number of patients discharged from the PCMHI clinic upon achieving therapeutic goals or discharged to specialty mental health due to therapeutic failure or adverse drug events with first- and second-line psychotropic agents.
Results: When contrasting the end points, there was a 60% increase in the number of patients who achieved therapeutic goal and a 32% decrease in the number of patients discharged to specialty mental health clinic postincorporation of CPS into PCMHI as compared to preincorporation of CPS (P = .024).
Discussion: The results support the significance of CPS in the PCMHI in providing pharmacotherapy, patient education, and medication monitoring for managing psychiatric conditions, such as depression, anxiety, and insomnia. In addition, patients had greater accessibility to medication and frequent monitoring and follow-up, ultimately improving patient outcomes.
High‐resolution seismic tomography of the 2015 Mw7.8 Gorkha earthquake, Nepal: Evidence for the crustal tearing of the Himalayan rift
Authors: Pei Shunping , Liu Hongbing , Bai Ling , Liu Yanbing , Sun Quan 
Published: August 2016

AbstractThe Mw7.8 Gorkha earthquake struck Nepal and ruptured the boundary between the Indian and Eurasian plates. We conducted 2‐D Pg wave tomography to clarify the seismogenic structure and try to understand causal mechanisms for this large earthquake, using the aftershock data recorded by 15 broadband seismic stations located near the China‐Nepal border. Our high‐resolution results show that coseismic slip area of the main shock is consistent with the high P wave velocity anomaly, and the region of maximum slip has a larger area with higher velocity than the region of initial slip, possibly resulting in the dominant low‐frequency radiation of energy observed after the dominant high‐frequency radiation of energy in the source rupture process. The boundary between these regions of contrasting high and low seismic velocity anomalies suggests a potential crustal tearing at the southern end of the Tangra Yum Co Rift, possibly resulting from different thrust speeds in the Greater Himalaya.
Comparison of coseismic near‐field and off‐fault surface deformation patterns of the 1992Mw7.3 Landers and 1999Mw7.1 Hector Mine earthquakes: Implications for controls on the distribution of surface strain
Authors: Milliner C. W. D. , Dolan J. F. , Hollingsworth J. , Leprince S. , Ayoub F. 
Published: August 2016

AbstractSubpixel correlation of preevent and postevent air photos reveal the complete near‐field, horizontal surface deformation patterns of the 1992Mw7.3 Landers and 1999Mw7.1 Hector Mine ruptures. Total surface displacement values for both earthquakes are systematically larger than “on‐fault” displacements from geologic field surveys, indicating significant distributed, inelastic deformation occurred along these ruptures. Comparison of these two data sets shows that 46 ± 10% and 39 ± 22% of the total surface deformation were distributed over fault zones averaging 154 m and 121 m in width for the Landers and Hector Mine events, respectively. Spatial variations of distributed deformation along both ruptures show correlations with the type of near‐surface lithology and degree of fault complexity; larger amounts of distributed shear occur where the rupture propagated through loose unconsolidated sediments and areas of more complex fault structure. These results have basic implications for geologic‐geodetic rate comparisons and probabilistic seismic hazard analysis.
Trends of perchlorate in Antarctic snow: Implications for atmospheric production and preservation in snow
Authors: Jiang Su , Cox Thomas S. , Cole‐Dai Jihong , Peterson Kari M. , Shi Guitao 
Published: August 2016

AbstractPerchlorate concentration ranges from a few to a few hundred ng kg−1 in surface and shallow‐depth snow at three Antarctic locations (South Pole, Dome A, and central West Antarctica), with significant spatial variations dependent on snow accumulation rate and/or atmospheric production rate. An obvious trend of increasing perchlorate since the 1970s is seen in South Pole snow. The trend is possibly the result of stratospheric chlorine levels elevated by anthropogenic chlorine emissions; this is supported by the timing of a similar trend at Dome A. Alternatively, the trend may stem from postdepositional loss of snowpack perchlorate or a combination of both. The possible impact of stratospheric chlorine is consistent with evidence of perchlorate production in the stratosphere. Additionally, perchlorate concentration appears to be directly affected by the springtime Antarctic ozone hole. Therefore, perchlorate variations in Antarctic snow are likely linked to stratospheric chemistry and ozone over the Antarctic.
Stress rotations due to the M6.5 foreshock and M7.3 main shock in the 2016 Kumamoto, SW Japan, earthquake sequence
Authors: Yoshida Keisuke , Hasegawa Akira , Saito Tatsuhiko , Asano Youichi , Tanaka Sachiko , Sawazaki Kaoru , Urata Yumi , Fukuyama Eiichi 
Published: August 2016

AbstractA shallow M7.3 event with a M6.5 foreshock occurred along the Futagawa‐Hinagu fault zone in Kyushu, SW Japan. We investigated the spatiotemporal variation of the stress orientations in and around the source area of this 2016 Kumamoto earthquake sequence by inverting 1218 focal mechanisms. The results show that the σ3 axis in the vicinity of the fault plane significantly rotated counterclockwise after the M6.5 foreshock and rotated clockwise after the M7.3 main shock in the Hinagu fault segment. This observation indicates that a significant portion of the shear stress was released both by the M6.5 foreshock and M7.3 main shock. It is estimated that the stress release by the M6.5 foreshock occurred in the shallower part of the Hinagu fault segment, which brought the stress concentration in its deeper part. This might have caused the M7.3 main shock rupture mainly along the deeper part of the Hinagu fault segment after 28 h.
Heliospheric plasma sheet (HPS) impingement onto the magnetosphere as a cause of relativistic electron dropouts (REDs) via coherent EMIC wave scattering with possible consequences for climate change mechanisms
Authors: Tsurutani B. T. , Hajra R. , Tanimori T. , Takada A. , Remya B. , Mannucci A. J. , Lakhina G. S. , Kozyra J. U. , Shiokawa K. , Lee L. C. , Echer E. , Reddy R. V. , Gonzalez W. D. 
Published: August 2016

AbstractA new scenario is presented for the cause of magnetospheric relativistic electron decreases (REDs) and potential effects in the atmosphere and on climate. High‐density solar wind heliospheric plasmasheet (HPS) events impinge onto the magnetosphere, compressing it along with remnant noon‐sector outer‐zone magnetospheric ~10‐100 keV protons. The betatron accelerated protons generate coherent electromagnetic ion cyclotron (EMIC) waves through a temperature anisotropy (T⊥/T|| > 1) instability. The waves in turn interact with relativistic electrons and cause the rapid loss of these particles to a small region of the atmosphere. A peak total energy deposition of ~3 × 1020 ergs is derived for the precipitating electrons. Maximum energy deposition and creation of electron‐ion pairs at 30‐50 km and at < 30 km altitude are quantified. We focus the readers' attention on the relevance of this present work to two climate change mechanisms. Wilcox et al. (1973) noted a correlation between solar wind heliospheric current sheet (HCS) crossings and high atmospheric vorticity centers at 300 mb altitude. Tinsley et al. () has constructed a global circuit model which depends on particle precipitation into the atmosphere. Other possible scenarios potentially affecting weather/climate change are also discussed.
Crustal deformation dynamics and stress evolution during seamount subduction: High‐resolution 3‐D numerical modeling
Authors: Ruh Jonas B. , Sallarès Valentí , Ranero César R. , Gerya Taras 
Published: August 2016

AbstractSeamounts or submarine volcanoes frequently collide with the overriding crust along presently active subduction zones locally modifying stress and permanent deformation patterns. Dynamics of this process is not fully understood, and several end‐member scenarios of seamount‐crust interaction are proposed. Here we use high‐resolution 3‐D numerical models to investigate evolution of crustal deformation and stress distribution within the upper plate induced by the underthrusting of subducting seamounts. The dynamical effects of the upper plate strength, subduction interface strength, and strain weakening of the crust are investigated. Experiment results demonstrate that characteristic crustal fracturing patterns formed in response to different seamount‐crust interaction scenarios. Indenting seamounts strongly deform the overriding plate along a corridor as wide as the underthrusting seamount by constantly shifting subvertical shear zones rooted at the seamount extensions. A reentrant develops during initial seamount collision. A topographic bulge atop the seamount and lateral ridges emerge from further seamount subduction. Obtained stress pattern shows areas of large overpressure above the rearward and large underpressure above the trenchward flank of the seamount. Results of numerical experiments are consistent with seismic reflection images and seismic velocity models of the upper plate in areas of seamount subduction along the Middle America Trench and give important insights into the long‐lasting question, whether subducting seamounts and rough seafloor act as barriers or asperities for megathrust earthquakes.
Method of analytical regularization in computational photonics
Authors: Nosich Alexander I. 
Published: August 2016

AbstractWe discuss the advantages of the conversion of electromagnetic field problems to the Fredholm second‐kind integral equations (analytical regularization) and Fredholm second‐kind infinite‐matrix equations (analytical preconditioning). Special attention is paid to specific features of the characterization of metals and dielectrics in the optical range and their effect on the problem formulation and on the methods applicable to the mentioned conversion.
Ethylbenzene [MAK Value Documentation, 2001]
Authors: Hartwig A. ,   MAK Commission
Published: August 2016

Abstract
The article contains sections titled:

Toxic Effects and Mode of Action

Mechanism of Action

Toxicokinetics and Metabolism

Effects in Humans

Single exposures

Repeated exposure

Allergenic effects

Carcinogenicity

Animal Experiments and in vitro Studies

Subacute, subchronic and chronic toxicity

Genotoxicity

In vitro

In vivo

Genotoxicity of ethylbenzene metabolites

Reproductive and Developmental Toxicity

Fertility

Developmental toxicity

Carcinogenicity

Short‐term studies

Long‐term studies

Carcinogenicity studies with ethylbenzene metabolites or mixtures

Other Effects

Manifesto (MAK value/classification)
Isoflurane [MAK Value Documentation, 2007]
Authors: Hartwig A. ,   MAK Commission
Published: August 2016

AbstractThe article contains sections titled:Toxic Effects and Mode of ActionMechanism of ActionToxicokinetics and MetabolismAbsorptionMetabolismEffects in HumansBiomonitoringSingle exposureRepeated exposuresOther effectsAnimal Experiments and in vitro StudiesAcute toxicityReproductive toxicityManifesto (MAK value, classification)
Pyrethrum [MAK Value Documentation, 2008]
Authors: Hartwig A. ,   MAK Commission
Published: August 2016

AbstractThe article contains sections titled:Toxic Effects and Mode of ActionMechanism of ActionToxicokinetics and MetabolismEffects in HumansSingle exposuresRepeated exposureLocal effects on skin and mucous membranesAllergenic effectsDevelopmental and reproductive toxicityGenotoxicityCarcinogenicityAnimal Experiments and in vitro StudiesAcute toxicitySubacute, subchronic and chronic toxicityEffects on skin and mucous membranesAllergenic effectsReproductive and developmental toxicityGenotoxicityCarcinogenicityManifesto (MAK value, classification)
Diagnostic utility of ASL‐MRI and FDG‐PET in the behavioral variant of FTD and AD
Authors: Tosun Duygu , Schuff Norbert , Rabinovici Gil D. , Ayakta Nagehan , Miller Bruce L. , Jagust William , Kramer Joel , Weiner Michael M. , Rosen Howard J. 
Published: August 2016

AbstractObjectiveTo compare the values of arterial spin‐labeled (ASL) MRI and fluorodeoxyglucose (FDG) PET in the diagnosis of behavioral variant of frontotemporal dementia (bvFTD) and Alzheimer's disease (AD).MethodsPartial least squares logistic regression was used to identify voxels with diagnostic value in cerebral blood flow (CBF) and cerebral metabolic rate of glucose (CMRgl) maps from patients with bvFTD (n = 32) and AD (n = 28), who were compared with each other and with cognitively normal controls (CN, n = 15). Diagnostic values of these maps were compared with each other.ResultsRegions that differentiated each disorder from controls were similar for CBF and CMRgl. For differentiating AD from CN, the areas under the curve (AUC) for CBF (0.89) and CMRgl (0.91) were similar, with similar sensitivity (CBF: 86%, CMRgl: 78%) and specificity (CBF: 92%, CMRgl: 100%). Likewise, for differentiating bvFTD from CN performances of CBF (AUC = 0.83) and CMRgl (AUC = 0.85) were equivalent, with similar sensitivity (CBF: 78%, CMRgl: 79%) and specificity (CBF: 92%, CMRgl: 100%). In differentiating bvFTD from AD, classification was again similar for CBF (AUC = 0.87) and CMRgl (AUC = 0.79), as were sensitivity (CBF: 83%, CMRgl: 89%) and specificity (CBF: 93%, CMRgl: 78%). None of the differences in any performance measure were statistically significant.InterpretationASL‐MRI has similar diagnostic utility as FDG‐PET in the diagnosis of AD and bvFTD. Continued development of ASL‐MRI as a diagnostic tool for neurodegenerative dementias is warranted.
Mild and Direct Multiple Deuterium‐Labeling of Saturated Fatty Acids
Authors: Yamada Tsuyoshi , Park Kwihwan , Yasukawa Naoki , Morita Kosuke , Monguchi Yasunari , Sawama Yoshinari , Sajiki Hironao 
Published: August 2016

AbstractWe have established a mild and direct platinum on carbon (Pt/C)‐catalyzed multi‐deuterium labeling of various saturated fatty acids including bioactive compounds with high deuterium efficiencies in a mixed solvent of isopropyl alcohol and deuterium oxide (i‐PrOH)/D2O under neutral conditions at 120 °C without the external addition of deuterium or hydrogen gas.magnified image
Urban American Indian Community Perspectives on Resources and Challenges for Youth Suicide Prevention
Authors: Burrage Rachel L. , Gone Joseph P. , Momper Sandra L. 
Published: August 2016

AbstractAmerican Indian (AI) youth have some of the highest rates of suicide of any group in the United States, and the majority of AI youth live in urban areas away from tribal communities. As such, understanding the resources available for suicide prevention among urban AI youth is critical, as is understanding the challenges involved in accessing such resources. Pre‐existing interview data from 15 self‐identified AI community members and staff from an Urban Indian Health Organization were examined to understand existing resources for urban AI youth suicide prevention, as well as related challenges. A thematic analysis was undertaken, resulting in three principal themes around suicide prevention: formal resources, informal resources, and community values and beliefs. Formal resources that meet the needs of AI youth were viewed as largely inaccessible or nonexistent, and youth were seen as more likely to seek help from informal sources. Community values of mutual support were thought to reinforce available informal supports. However, challenges arose in terms of the community's knowledge of and views on discussing suicide, as well as the perceived fit between community values and beliefs and formal prevention models.
NMR Structure of a Triangulenium‐Based Long‐Lived Fluorescence Probe Bound to a G‐Quadruplex
Authors: Kotar Anita , Wang Baifan , Shivalingam Arun , Gonzalez‐Garcia Jorge , Vilar Ramon , Plavec Janez 
Published: August 2016

AbstractAn NMR structural study of the interaction between a small‐molecule optical probe (DAOTA‐M2) and a G‐quadruplex from the promoter region of the c‐myc oncogene revealed that they interact at 1:2 binding stoichiometry. NMR‐restrained structural calculations show that binding of DAOTA‐M2 occurs mainly through π–π stacking between the polyaromatic core of the ligand and guanine residues of the outer G‐quartets. Interestingly, the binding affinities of DAOTA‐M2 differ by a factor of two for the outer G‐quartets of the unimolecular parallel G‐quadruplex under study. Unrestrained MD calculations indicate that DAOTA‐M2 displays significant dynamic behavior when stacked on a G‐quartet plane. These studies provide molecular guidelines for the design of triangulenium derivatives that can be used as optical probes for G‐quadruplexes.
Type Number Based Steady‐State Error Analysis on Fractional Order Control Systems
Authors: Pan Jinwen , Gao Qing , Qiu Jianbin , Wang Yong 
Published: August 2016

AbstractIn this paper, steady‐state error of fractional order control systems (FOCSs) is analyzed based on the concept of type number. Some practical definitions of the reference and the error for FOCSs with non‐unity feedback are first given. Based on these definitions, the type number concept is first introduced to FOCSs with non‐unity feedback. Then steady‐state error of various types of FOCSs are analyzed respectively via type number concept. It is also shown that FOCSs with type number more than 1 are not able to track particular reference without changing the sign of the tracking error.
Sustaining Competitive Advantage Through Corporate Environmental Performance
Authors: Yadav Prayag Lal , Han Seung Hun , Kim Hohyun 
Published: August 2016

AbstractThis research investigates the relationship between a firm's environmental efforts and the sustainability of its competitive advantage by analyzing the effects of change in firm environmental performance on the persistence of profitability growth. We find that environmental resources allow a firm with superior financial performance to sustain its competitive advantage, and also complement the efforts of a poorly performing firm to hasten recovery from inferior financial performance. Our findings further indicate that firms attain such positive effects through enhanced profit margins resulting from improved environmental performance. Additionally, we observe that a corporate strategy of improving environmental performance demonstrates management's responsibility to maximize the shareholder wealth of a well‐performing firm. The results provide valuable insights to align environmental activities towards developing unique resources for sustaining the competitive advantage. The study provides an empirical support for creating economic value by benefiting the environment. Copyright © 2016 John Wiley & Sons, Ltd and ERP Environment
The Impact of Board Structure on Corporate Social Responsibility: A Temporal View
Authors: Galbreath Jeremy 
Published: August 2016

AbstractTime plays an important role in corporate social responsibility (CSR) decisions. In the context of time and the boardroom, the consideration of CSR can be affected by board structure. For example, because of considerable short‐term pressures, this study posits that insiders on the board are less likely to prioritize the longer‐term time horizons needed to affect CSR. Following this perspective, a hypothesis is put forth that insiders generally have temporal orientations that are more short term in nature and that they therefore have a negative effect on CSR. A study of 300 of Australia's largest firms confirmed this hypothesis. However, when inside director compensation linked to environmental and social metrics and inside director CSR training are introduced as moderating variables, their interactive effects lead to positive results: both positively moderate the negative insider–CSR relationship in environmental and social dimensions. The study contributes to a temporal view of boards of directors, as well as to corporate governance and CSR. Copyright © 2016 John Wiley & Sons, Ltd and ERP Environment
Site‐Specific Labeling of MicroRNA Precursors: A Structure–Activity Relationship Study
Authors: Menzi Mirjam , Pradère Ugo , Wang Yuluan , Fischer Matteo , Baumann Fabienne , Bigatti Martina , Hall Jonathan 
Published: August 2016

AbstractFunctionalized oligoribonucleotides are essential tools in RNA chemical biology. Various synthetic routes have been developed over recent years to conjugate functional groups to oligoribonucleotides. However, the presence of the functional group on the oligoribonucleotide backbone can lead to partial or total loss of biological function. The limited knowledge concerning the positioning of functional groups therefore represents a hurdle for the development of oligoribonucleotide chemical tools. Here we describe a systematic investigation of site‐specific labeling of pre‐miRNAs to identify positions for the incorporation of functional groups, in order not to hinder their processing into active mature miRNAs.
The Conversion of Methanol into Higher Hydrocarbons Catalyzed by Gold
Authors: Gabriel Sam , Scurrell Michael S. 
Published: August 2016

AbstractGold/zinc oxide catalysts prepared by coprecipitation and containing gold particles of approximately 6 nm in diameter are active in the conversion of methanol to higher hydrocarbons under mild conditions. Conversions exceed 97 % under the selected experimental conditions at reaction temperatures of 350 °C, with a turnover number of 0.02 s−1. Both alkanes and alkenes up to C6 are formed, with a selectivity of approximately 44 %C hydrocarbons and 56 %C dimethyl ether. The addition of zeolite‐Y in composite catalysts modifies the product spectrum slightly. Ethene and propene dominate the alkenes formed above 450 °C if a 1:1 HY:Au/ZnO composite is used; the dominant alkane under these conditions is methane. At 475 °C only three hydrocarbons are present with selectivities of 13 (methane), 39 (ethene), and 48 % (propene). The carbon−carbon bond formation was not seen in earlier work when syngas (CO plus H2) was converted with the same Au/ZnO catalyst at high pressure to form mixtures of alcohols and hydrocarbons. This suggests that the formation of higher hydrocarbons from methanol is inhibited in the presence of CO and/or H2, probably due to competitive CO adsorption on the gold surface.