bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual wide‐band miniaturized negative group delay circuit using open circuit stubs
Authors: Taher Hany , Farrell Ronan 
Published: January 2018

AbstractIn this letter, dual band negative group delay circuit (DBNGDC) utilizing a couple of one quarter guided wave length (
) open circuited stubs (OCSs) is presented. The centre frequencies (
) are fully controlled with the stub lengths. On the other hand, the target negative group delay (NGD) is obtained using couple of resistors (
) that connect each OCS to the main microstrip line. The designed DBNGDC accomplishes 52% size diminution compared with smallest size has ever been achieved before. Moreover, 0.2 and 0.4 GHz zero‐NGD bandwidths (BW) are achieved.
Liquids electrical characterization sensor using a hybrid SIW resonant cavity
Authors: Caleffo Ricardo Caranicola , Correra Fatima Salete 
Published: January 2018

AbstractA new sensor based on substrate integrated waveguide (SIW) technology is proposed as an option for liquids electrical characterization. The sensor employs a rectangular waveguide resonant cavity filled with air, with two opposite side walls implemented by closely spaced metallic vias. The resulting structure is a hybrid SIW resonant cavity. The two noncontinuous walls of the hybrid SIW cavity allow the liquid insertion, filling its entire internal volume. The resonance frequency of the hybrid SIW cavity is used to determine the dielectric constant of the liquid to be characterized. A sensor using a hybrid SIW cavity operating in TE101 mode was designed to resonate at 5.9 GHz when filled with air. The sensor was employed to measure the dielectric constant of binary mixtures of distilled water and ethanol. Dielectric constants ranging from 21 to 79 were obtained, corresponding to measured resonance frequencies from 1,247 to 647 MHz, respectively. Good agreement was observed between computational electromagnetic simulation and experimental results. The dependence of the volumetric fraction of ethanol in the binary mixture on the sensor resonance frequency was expressed using a third‐order polynomial approximation.
Compact dual band slotted triangular monopole antenna for RFID applications
Authors: Dehmas M. , Azrar A. , Mouhouche F , Djafri K. , Challal M. 
Published: January 2018

AbstractThis paper presents a compact monopole antenna for radio frequency identification (RFID) systems. The proposed antenna is a dual band structure that can operate in the frequency ranges [0.797–1.004 GHz] and [2.234–2.934 GHz]. Consequently, the antenna covers widely the two UHF bands dedicated for RFID applications which are [0.860–0.960 GHz] and [2.380–2.520 GHz]. Moreover, the antenna is compact and its wide band nature makes it suitable for several applications other than RFID (GSM, UMTS, Wi‐Fi, Bluetooth, etc.). The proposed antenna has been fabricated and its reflection coefficient measured where a good agreement is observed with the simulated results.
Vivaldi tapered slot reflectarray loaded with dumbbell‐shaped ring resonator
Authors: Phua Y. N. , Lim E. H. , Chung B. K. 
Published: January 2018

AbstractThe Vivaldi tapered slot antenna is incorporated with a dumbbell‐shaped microstrip ring resonator for designing a reflectarray that can achieve a maximum phase range of 371° and a −1‐dB gain bandwidth of 10.6%. Use of travelling‐wave radiator has made possible full phase range and low phase sensitivity.
A directivity enhanced structure for the Vivaldi antenna using coupling patches
Authors: Gao Chong , Li En , Zhang Yunpeng , Guo Gaofeng 
Published: January 2018

AbstractA novel structure to improve the directivity of the Vivaldi antenna by adding three metal patches on the end‐fire is introduced. The two side patches that were close to the radiator change the E‐field distribution of the traveling wave, and the middle patch was a director. The strong coupling between the radiator and side patches led to the constraint of much E‐field energy between the side coupling patches, and this structure reduces the current on the end of radiation aperture. Compared with the other antennas, the Vivaldi antenna with the two side coupling patches did not compromise the frequency range, but decreased the radiation of the side lobes especially at high frequencies. The measured results showed that this proposed antenna operated in an ultra‐wide frequency range of 2 GHz to 18.7 GHz. The directivity of the proposed antenna has been greatly improved, with a maximum increment of 4 dB at 15 GHz. This enhanced structure showed good universality for the other Vivaldi antennas.
Current tunable barium hexaferrite millimeter wave resonator
Authors: Popov M. A. , Zavislyak I. V. , Srinivasan G. 
Published: January 2018

AbstractThis report is on non‐linear magneto‐electric (ME) interactions due to an electric current in single crystal M‐type barium hexaferrite (BaM). The interaction results in variations in the magnetic order parameters and manifests as tuning of magnetic modes in a BaM resonator in the U‐band. A DC current along the c‐axis of the ferrite is found to tune the frequency of the magnetic mode by 400 MHz when the sample is in the single‐domain state and by 70 MHz in the multi‐domain state for currents up to 20 mA and applied voltages up to 75 V. The current tuning of the frequency is found to be linear with electric power for both single‐domain and multi‐domain resonances. The shift in mode frequency due to current is found to be an order of magnitude higher than shift that could be attributed to Joule heating. The current tuning of the resonator demonstrated here is of interest for miniature, self‐biased millimeter wave ferrite devices.
Novel wideband chaotic approach LNA with microcontroller compatibility for 5G wireless secure communication
Authors: Jayawickrama Chamindra , Kumar Sandeep , Song Hanjung 
Published: January 2018

AbstractThe tremendous growth of recent technologies toward secure communication networks requires two application goals: (1) encrypted message signal and (2) wide bandwidth operation. This work proposes a wide bandwidth disembodied polynomial chaos approach low‐noise amplifier (LNA) with microcontroller compatibility for 5G wireless secure communication. Two different architectures are proposed for achieve desired goal. First architecture approach uses three‐state variable Lorenz system which novitiate into discrete mode by using Euler method and make compatibility with microcontroller. The characteristics of output chaotic waveforms from first approach realized by using bifurcation and Lyapunov exponent methods. The propose first novel design methodology reproduce its dynamical behavior with conventional continuous‐time system and provides three output chaotic states which is used to encrypt message at the physical layer and achieves security in the telecommunication technologies. While in second architecture, LNA is designed using disembodied polynomial chaos approach which reproduce chaotic output signal over wide bandwidth ranging from 2 to 10 GHz. The LNA is implemented and fabricated using TSMC 45 nm commercial process and reveals minimum noise figure up to 1.5 dB. The fabrication chip of chaos approach LNA under the power consumption of 3.2 mW made good correlation with simulation ones.
Study of a parasitic U‐slot patch array antenna with characteristic mode analysis
Authors: Yeung Sai Ho , Wang Chao‐Fu 
Published: January 2018

AbstractThis letter presents and analyses a novel parasitic U‐slot patch array antenna, designed by combining the characteristic of U‐slot patch antenna and the characteristic of parasitically coupled antenna elements. Characteristic mode analysis is performed on the novel antenna to reveal the potential of the new radiating structure.
Reduced size of the λg/4 transmission line using immitance scaling for RF device applications
Authors: Lee Tae‐Hyeon , Yoon Ki‐Cheol , Son Kwang‐Chul 
Published: January 2018

AbstractThis article presents the proposed reduced size of the λg/4 transmission line (TL) using immitance scaling. The proposed compact size of the TL is used for immitance scaling, which is composed of folded open stubs and series TL. It can be the design for distributed elements instead of lumped elements in a shunt capacitor, which is therefore called the folded open stubs. The proposed compact TL can be applied to a Wilkinson power divider (combiner), hybrid branch line coupler, and stub band‐pass filter in microwave applications.
Simplified optical generation of microwave signal based on polarization multiplexing using an optical phase modulator
Authors: Xu Wenjing , Gao Xinlu , Zhao Mingyang , Xie Mutong , Huang Shanguo 
Published: January 2018

AbstractA new method to generate microwave signal with frequency doubled of the RF signal using an optical phase modulator by simply adjusting the polarization angle of the polarizer without any optical filters is experimentally proposed. The optical carrier is 19 dB lower than the 2 first‐order sidebands, which is better than the traditional optical carrier suppression double sideband modulation scheme. After detected by a high speed photodiode, a high spectrum purity 28 GHz microwave signal is generated easily. In addition, as pure optical carrier can also be recovered easily, the proposed scheme is cost‐effective and may be useful for the radio over fiber system with wavelength reuse.
Electromagnetic band gap waveguide and bends substrate integrated waveguide
Authors: Grine Farouk , Djerafi Tarek , Khalef Rostom , Benhabiles Mohamed Ttaoufik , Riabi Mohamed Lahdi 
Published: January 2018

AbstractA planar waveguide and a rounded bend is proposed, designed, and implemented through a hybrid structure of substrate integrated waveguide (SIW) and electromagnetic bandgap (EBG) material. In order to design the EBG waveguide, a square lattice of air holes situated between two metal plates is used. The SIW line and bend are inserted on EBG waveguide to enhance performance. These devices were fabricated and measured. The experimental results show a homogeneous agreement with the simulation. The combination EBG‐SIW covers almost the whole EBG bandwidth of 6 GHz (17%) around 35 GHz. The proposed hybrid integration technique presents a competitive candidate for the development of millimeter‐wave circuits and systems.
The economic burden of overactive bladder in the United States: A systematic literature review
Authors: Powell Lauren C. , Szabo Shelagh M. , Walker David , Gooch Katherine 
Published: January 2018

AimsOveractive bladder (OAB) affects up to 17% of the United States (US) population. This study aimed to synthesize estimates of direct and indirect costs of OAB in the US and compare costs among those with and without OAB.MethodsA systematic review was performed using MEDLINE/PubMed and Embase, from 2003 to 2016, following PRISMA guidelines. The target population was adults with idiopathic OAB or urge urinary incontinence from the US. Data were extracted on study and patient characteristics, all‐cause and OAB‐specific direct costs, resource use, and indirect costs. Costs were inflated to a common price year of 2016 USD.ResultsEighteen studies were included. Mean insurer paid all‐cause total direct healthcare costs ranged from 8168 to 15 569 USD, and OAB‐specific costs ranged from 656 to 860 USD per‐patient annually. Estimates of the incremental costs for OAB patients compared to non‐OAB comparators ranged from 43% to 117%. One study estimated total annual indirect costs of OAB at 11 134 USD per‐patient.ConclusionsThe range of direct healthcare costs reported for managing patients with OAB varied, but was relatively small given the differing contributing data sources, study designs, and cost definitions. Direct costs were consistently higher among patients with OAB versus non‐OAB comparisons, from a 1.4‐ to >2‐fold increase annually. OAB‐specific costs made up a small proportion of all‐cause costs, highlighting the clinical and economic impact of OAB‐related conditions such as falls, urinary tract infection, and depression. Few studies were identified that examined the indirect costs of OAB in the US.
Pharmacist Intervention for Blood Pressure Control in Patients with Diabetes and/or Chronic Kidney Disease
Authors: Anderegg Maxwell D. , Gums Tyler H. , Uribe Liz , MacLaughlin Eric J. , Hoehns James , Bazaldua Oralia V. , Ives Timothy J. , Hahn David L. , Coffey Christopher S. , Carter Barry L. 
Published: January 2018

ObjectivesThe objectives of this study were to determine if hypertensive patients with comorbid diabetes mellitus (DM) and/or chronic kidney disease (CKD) receiving a pharmacist intervention had a greater reduction in mean blood pressure (BP) and improved BP control at 9 months compared with those receiving usual care; and compare Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC 7) guideline and 2014 guideline (JNC 8) BP control rates in patients with DM and/or CKD.MethodsThis cluster randomized trial included 32 medical offices in 15 states. Clinical pharmacists made treatment recommendations to physicians at intervention sites. This post hoc analysis evaluated mean BP and BP control rates in the intervention and control groups.Main resultsThe study included 335 patients (227 intervention, 108 control) when mean BP and control rates were evaluated by JNC 7 inclusion and control criteria. When JNC 8 inclusion and control criteria were applied, 241 patients (165 intervention, 76 control) remained and were included in the analysis. The pharmacist‐intervention group had significantly greater mean systolic blood pressure reduction compared with usual care at 9 months (8.64 mm Hg; 95% confidence interval [CI] −12.8 to −4.49, p<0.001). The pharmacist‐intervention group had significantly higher BP control at 9 months than usual care by either the JNC 7 or JNC 8 inclusion and control groups (adjusted odds ratio [OR] 1.97, 95% CI 1.01–3.86, p=0.0470 and OR 2.16, 95% CI 1.21–3.85, p=0.0102, respectively).Principal conclusionsThis study demonstrated that a physician‐pharmacist collaborative intervention was effective in reducing mean systolic BP and improving BP control in patients with uncontrolled hypertension with DM and/or CKD, regardless of which BP guidelines were used.
Structure, function and evolution of the hemerythrin‐like domain superfamily
Authors: Alvarez‐Carreño Claudia , Alva Vikram , Becerra Arturo , Lazcano Antonio 
Published: January 2018

AbstractHemerythrin‐like proteins have generally been studied for their ability to reversibly bind oxygen through their binuclear nonheme iron centers. However, in recent years, it has become increasingly evident that some members of the hemerythrin‐like superfamily also participate in many other biological processes. For instance, the binuclear nonheme iron site of YtfE, a hemerythrin‐like protein involved in the repair of iron centers in Escherichia coli, catalyzes the reduction of nitric oxide to nitrous oxide, and the human F‐box/LRR‐repeat protein 5, which contains a hemerythrin‐like domain, is involved in intracellular iron homeostasis. Furthermore, structural data on hemerythrin‐like domains from two proteins of unknown function, PF0695 from Pyrococcus furiosus and NMB1532 from Neisseria meningitidis, show that the cation‐binding sites, typical of hemerythrin, can be absent or be occupied by metal ions other than iron. To systematically investigate this functional and structural diversity of the hemerythrin‐like superfamily, we have collected hemerythrin‐like sequences from a database comprising fully sequenced proteomes and generated a cluster map based on their all‐against‐all pairwise sequence similarity. Our results show that the hemerythrin‐like superfamily comprises a large number of protein families which can be classified into three broad groups on the basis of their cation‐coordinating residues: (a) signal‐transduction and oxygen‐carrier hemerythrins (H‐HxxxE‐HxxxH‐HxxxxD); (b) hemerythrin‐like (H‐HxxxE‐H‐HxxxE); and, (c) metazoan F‐box proteins (H‐HExxE‐H‐HxxxE). Interestingly, all but two hemerythrin‐like families exhibit internal sequence and structural symmetry, suggesting that a duplication event may have led to the origin of the hemerythrin domain.
Protective effect of carvedilol alone and coadministered with diltiazem and prednisolone on doxorubicin and 5‐fluorouracil‐induced hepatotoxicity and nephrotoxicity in rats
Authors: Akindele Abidemi J. , Oludadepo Gabriel O. , Amagon Kennedy I. , Singh Dhirendra , Osiagwu Daniel D. 
Published: January 2018

AbstractThis study investigated the protective effects of carvedilol alone and coadministered with prednisolone and diltiazem on doxorubicin (DOX) and 5‐fluorouracil (5‐FU)‐induced toxicity. Each of 2 pools of 70 female rats were randomly allotted into 10 groups of 7 animals each and treated as follows: Group 1: normal saline (10 mL/kg); Group 2: normal saline and DOX (40 mg/kg)/5‐FU (20 mg/kg) alone; Group 3: gallic acid (200 mg/kg) and DOX/5‐FU; Group 4: carvedilol (0.075 mg/kg) and DOX/5‐FU; Group 5: carvedilol (0.15 mg/kg) and DOX/5‐FU; Group 6: carvedilol (0.30 mg/kg) and DOX/5‐FU; Group 7: diltiazem (3.43 mg/kg) and DOX/5‐FU; Group 8: diltiazem (3.43 mg/kg), carvedilol (0.15 mg/kg), and DOX/5‐FU; Group 9: prednisolone (0.57 mg/kg) and DOX/5‐FU; and Group 10: prednisolone (0.57 mg/kg), carvedilol (0.15 mg/kg), and DOX/5‐FU. Treatments were done p.o. for 16/14 days for the DOX/5‐FU models. DOX/5‐FU was administered i.p. to the rats in Groups 2‐10 on day 14/10‐14. On day 17/15 (DOX/5‐FU), blood samples were collected, and liver and kidneys of rats were harvested for antioxidant and histopathological assessments. Carvedilol alone and coadministered with prednisolone significantly (P < .05) decreased alanine aminotransferase level compared with administration of DOX alone. Carvedilol alone and coadministered with diltiazem significantly (P < .05) decreased creatinine level compared with administration of DOX/5‐FU alone. Carvedilol alone and coadministered with diltiazem and prednisolone significantly (P < .05) increased the level of hepatic superoxide dismutase and catalase, and decreased malondialdehyde compared with DOX administration alone. Histopathological observations correlated with results of biochemical and antioxidant analyses. Carvedilol administered alone and coadministered with diltiazem and prednisolone reduced the effect of DOX/5‐FU‐induced hepatic and renal toxicities due to enhanced in vivo antioxidant activity. The protective effect was more prominent in the doxorubicin model compared with the 5‐fluorouracil test. Coadministration of carvedilol with either diltiazem or prednisolone did not show better protection relative to carvedilol alone.
Effects of seed mixture sowing with resistant and susceptible rice on population dynamics of target planthoppers and non‐target stemborers and leaffolders
Authors: Li Zhuo , Wan Guijun , Wang Long , Parajulee Megha N , Zhao Zihua , Chen Fajun 
Published: January 2018

AbstractBACKGROUNDThe widespread planting of insect‐resistant crops has caused a dramatic shift in agricultural landscapes, thus raising concerns about the potential impact on both target and non‐target pests worldwide. In this study, we examined the potential effects of six seed mixture ratios of insect‐resistance dominance [100% (R100), 95% (S05R95), 90% (S10R90), 80% (S20R80), 60% (S40R60), and 0% (S100)] on target and non‐target pests in a 2‐year field trial in southern China.RESULTSThe occurrence of the target pests Nilaparvata lugens and Sogatella furcifera decreased with an increase in the ratio of resistant rice, and mixture ratios with ≥90% resistant rice significantly increased the pest suppression efficiency, with the lowest occurrences of the non‐target pests Sesamia inferens, Chilo suppressalis and Cnaphalocrocis medinalis for S100 and S10R90 seed mixture ratios. Furthermore, there were no significant differences in the 1000‐grain dry weight and grain yield between R100 and other treatments with ≥80% resistant seeds in the mixture (S20R80, S10R90 and S05R95).CONCLUSIONS10R90 produced a good yield and provided the most effective control of both target and non‐target pests, with the potential to significantly reduce the application of chemical pesticides for integrated pest management in paddy fields. It is further presumed that the strategy of seed mixture with resistant and susceptible rice would be advantageous for rice yield stability. © 2018 Society of Chemical Industry
Design, expression, and characterization of the hybrid antimicrobial peptide T‐catesbeianin‐1 based on FyuA
Authors: Xu Huihui , Tie Kunyuan , Zhang Yang , Feng Xin , Cao Yuan , Han Wenyu 
Published: January 2018

The overuse of antibiotics has resulted in the emergence of antibiotic‐resistant bacteria, which presents an urgent need for new antimicrobial agents. At present, antimicrobial peptides have attracted a great deal of attention from researchers. However, antimicrobial peptides often affect a broad range of microorganisms, including the normal flora in a host organism. In the present study, we designed a novel hybrid antimicrobial peptide, expressed the hybrid peptide, and studied its specific target. The hybrid peptide, named T‐catesbeianin‐1, which includes the FyuA‐binding domain of pesticin and the peptide catesbeianin‐1, was designed and expressed in Pichia pastoris X‐33. Then, we determined the antimicrobial activity, cytotoxicity, and specific target of the peptide. T‐catesbeianin‐1 has strong antimicrobial activity and binds to FyuA to inhibit or kill Escherichia coli present in clinical specimens and mixed‐species culture. In summary, these findings suggested that T‐catesbeianin‐1 might be promising and specific antibiotic agent for therapeutic application against fyuA+ E. coli.
Antifungal dipeptides incorporating an inhibitor of homoserine dehydrogenase
Authors: Skwarecki Andrzej S. , Schielmann Marta , Martynow Dorota , Kawczyński Marcin , Wiśniewska Aleksandra , Milewska Maria J. , Milewski Sławomir 
Published: January 2018

The antifungal activity of 5‐hydroxy‐4‐oxo‐l‐norvaline (HONV), exhibited under conditions mimicking human serum, may be improved upon incorporation of this amino acid into a dipeptide structure. Several HONV‐containing dipeptides inhibited growth of human pathogenic yeasts of the Candida genus in the RPMI‐1640 medium, with minimal inhibitory concentration values in the 32 to 64 μg mL−1 range. This activity was not affected by multidrug resistance that is caused by overexpression of genes encoding drug efflux proteins. The mechanism of antifungal action of HONV dipeptides involved uptake by the oligopeptide transport system, subsequent intracellular cleavage by cytosolic peptidases, and inhibition of homoserine dehydrogenase by the released HONV. The relative transport rates determined the anticandidal activity of HONV dipeptides.
Semi‐autonomous image‐guided brain tumour resection using an integrated robotic system: A bench‐top study
Authors: Hu Danying , Gong Yuanzheng , Seibel Eric J. , Sekhar Laligam N. , Hannaford Blake 
Published: January 2018

AbstractBackgroundComplete brain tumour resection is an extremely critical factor for patients' survival rate and long‐term quality of life. This paper introduces a prototype medical robotic system that aims to automatically detect and clean up brain tumour residues after the removal of tumour bulk through conventional surgery.MethodsWe focus on the development of an integrated surgical robotic system for image‐guided robotic brain surgery. The Behavior Tree framework is explored to coordinate cross‐platform medical subtasks.ResultsThe integrated system was tested on a simulated laboratory platform. Results and performance indicate the feasibility of supervised semi‐automation for residual brain tumour ablation in a simulated surgical cavity with sub‐millimetre accuracy. The modularity in the control architecture allows straightforward integration of further medical devices.ConclusionsThis work presents a semi‐automated laboratory setup, simulating an intraoperative robotic neurosurgical procedure with real‐time endoscopic image guidance and provides a foundation for the future transition from engineering approaches to clinical application.