bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating high-frequency quasi-periodic oscillations in the 6374 Å red coronal line observed during the total solar eclipse on August 21, 2017
Authors: Liang Yu 
Published: September 2024

Context. We present the results of the search for high-frequency quasi-periodic oscillations (HFQPOs) in the 6374-Å red line emission from the solar corona during the 2017 total solar eclipse (TSE).
Aims. The existence of HFQPOs of coronal intensity remains unclear. Motivated by previous observations, this paper focuses on searching for the HFQPOs (> 0.1 Hz) during the 2017 TSE.
Methods. Wavelet analysis tools were used to analyze the radiation intensity oscillations in different height layers, local regions of interest (such as the east coronal loop, west cavity, etc.), and coronal feature points as well as changes in oscillations along coronal feature structures and the kinematic wobble of the coronal magnetic features.
Results. We have observed oscillatory signals at multiple spatial locations, which reveal the existence of quasi-periodic slow magnetoacoustic waves. These signals display periods ranging from approximately 3 to 9 seconds, with a notable focus on periods around 4 seconds.
Conclusions. High-frequency quasi-periodic slow magnetoacoustic oscillations (with periods less than 9.63 seconds) have been identified in the inner corona (at heights less than 1.4 R⊙) in the 6374 Å red coronal line radiation.
G321.3–3.9: A new supernova remnant observed with multi-band radio data and in the SRG/eROSITA All-Sky Surveys
Authors: Mantovanini S. , Becker W. , Khokhriakova A. , Hurley-Walker N. , Anderson G. E. , Nicastro L. 
Published: September 2024

Aims. G321.3–3.9 was first identified as a partial shell at radio frequencies a few decades ago. Although it continued to be observed, no additional studies were undertaken until recently.
Methods. In this paper, we present results from a large selection of radio and X-ray data that cover the position of G321.3–3.9. We confirmed G321.3–3.9 as a new supernova remnant (SNR) using data collected by several radio surveys, spanning a frequency range from 200 to 2300 MHz. Stacked eROSITA data from four consecutive all-sky surveys (eRASS:4) provide spectro-imaging information in the energy band 0.2–8.0 keV.
Results. G321.3–3.9 has an elliptical shape with major and minor axes of approximately 1.°7 × 1.°1. From CHIPASS and S-PASS data, we calculate a spectral index α = −0.8 ± 0.2, consistent with synchrotron emission from an expanding shell in the radiative phase. The eROSITA data show an X-ray diffuse structure filling almost the entire radio shell. Based on our spectral analysis, we found the temperature to be approximately 0.6 keV and the column absorption density about 1021 cm−2. Comparing this absorption density to optical extinction maps, we estimated the distance to fall within the range of (1.0–1.7) kpc, considering the 1σ uncertainty range.
Impact of Amphiregulin on Oocyte Maturation and Embryo Quality: Insights from Clinical and Molecular Perspectives
Authors: Kljajic Marija , Ney Jasmin Teresa , Wagenpfeil Gudrun , Baus Simona , Solomayer Erich-Franz , Kasoha Mariz 
Published: September 2024

AbstractIdentifying non-invasive biomarkers which can predict the outcome of intracytoplasmic sperm injection (ICSI) is crucial, particularly in Germany where the challenges are intensified by the Embryo Protection Act. Recent research has highlighted biomarkers within the epidermal growth factor (EGF) family as central to follicular processes, although their predictive utility remains a subject of debate in the literature. Therefore, the primary objective of this study was to investigate the significance of amphiregulin concentrations in follicular fluid and gene expression in mural granulosa cells on oocyte maturation, fertilization, and embryo quality.A total of 33 women were recruited at the University Clinic of Saarland Fertility Center (Homburg, Germany). Follicular fluid aspiration consisted of single/individual aspiration of follicles, enabling a 1 : 1 correlation with retrieved oocytes. Follicular fluid and mural granulosa cell samples from 108 oocytes were analyzed. Amphiregulin levels were determined with enzyme-linked immunosorbent assay, while gene expression was analyzed with the StepOnePlus Real-Time PCR System using TaqMan Fast Advanced Master Mix assays.Results showed that amphiregulin concentrations affect oocyte maturation, fertilization, and embryo quality, while luteinizing hormone concentrations influence oocyte maturation, with significant differences identified between fertilized/unfertilized and good/poor embryo groups. Amphiregulin expression significantly impacts oocyte maturation, with downregulation observed in immature oocytes, while luteinizing hormone/chorionic gonadotropin receptor expression showed no significant differences between groups and did not influence maturation, fertilization, or embryo quality.These findings are very important for advancing infertility treatment, especially in Germany. The results for amphiregulin may provide prognostic insights which could be useful when selecting viable oocytes and embryos. This research underscores the importance of non-invasive biomarkers for optimizing ICSI outcomes and potentially enhancing the success rates of assisted reproductive technology.
Evaluating the Modified American Academy of Pediatrics Screening Algorithm for Critical Congenital Heart Disease
Authors: Hoff Hannah , Quary Sharon , Keesari Rohali , Oster Matthew E. 
Published: September 2024

Objective In 2018, an expert panel recommended two key modifications to the most used algorithm for screening neonates for critical congenital heart disease (CCHD). Our aim was to evaluate the outcomes of the modified algorithm compared with those of the original algorithm in a real-world setting.
Study Design We compared the performance characteristics of an original CCHD algorithm used to screen term neonates at a large hospital system between October 26, 2018, and October 15, 2020, and the recommended modified algorithm used between October 15, 2020, and June 30, 2022. We calculated sensitivity, specificity, false positive rate, proportion of false positives with non-CCHD illness, and error rates of test administration and interpretation for each algorithm.
Results Sensitivity was not significantly different between the modified algorithm compared with the original algorithm (40.00 vs. 12.50%, p ≥0.99), but specificity was lower (and hence false positive rate was higher) in the modified algorithm (99.91 vs. 99.98%, p < 0.001). Despite a higher false positive rate in the modified algorithm, the proportion of false positives with significant non-CCHD illness was similar (36.47 vs. 28.57%, p ≥0.99), a finding that translated to an increase in the number of cases of significant non-CCHD illness detected (11 cases out of 32,178 screens vs. 2 cases out of 32,984 screens). Error rates of test administration and interpretation were similar between the two algorithms.
Conclusion In this limited study, the modified algorithm for CCHD screening using pulse oximetry had a higher false positive rate than that of the original American Academy of Pediatrics algorithm. However, this higher rate led to an increased overall number of cases detected of significant non-CCHD illness.
Key Points
Nulliparous Individuals with Class III Obesity: Adverse Outcomes with Labor versus Planned Cesarean Delivery
Authors: Cagino Kristen A. , Chen Han-Yang , Becker Cabrina , Red Beverly , Chauhan Suneet P. , Mendez-Figueroa Hector 
Published: September 2024

Objective Individuals with class III obesity (body mass index [BMI] ≥ 40 kg/m2) are at increased risk of cesarean delivery (CD) and peripartum complications. We ascertained compositive neonatal and maternal adverse outcomes among individuals with class III obesity who labored versus had planned CD.
Study Design This was a retrospective cohort study from 2016 to 2021 using the National Vital Statistics System database. Nulliparous individuals with class III obesity prepregnancy were included if they had singleton, nonanomalous pregnancies and delivered at 37 to 41 weeks of gestation. Individuals were excluded if they had hypertensive disorders or diabetes. The primary outcome was a composite neonatal adverse outcome (CNAO), consisting of Apgar score less than 5 at 5 minutes, assisted ventilation > 6 hours, neonatal seizure, or neonatal death. The secondary outcome was a composite maternal adverse outcome (CMAO) that included admission to the intensive care unit, maternal transfusion, uterine rupture, or unplanned hysterectomy. A sensitivity analysis using a CMAO without transfusion was performed. A multivariable Poisson regression model was performed to calculate adjusted relative risks (aRRs) with 95% confidence intervals (CIs).
Results Of 192,298 individuals who met inclusion criteria, 169,676 (88.2%) labored and 22,622 (11.8%) had a planned CD. Compared with neonates delivered by planned CD, the risk of CNAO was significantly lower in those who delivered after labor (aRR: 0.79, 95% CI: 0.71–0.87). There was no significant difference in the risk of CMAO between groups (aRR: 1.11, 95% CI: 0.87–1.41). However, the risk of CMAO without transfusion was lower in individuals who labored (aRR: 0.57, 95% CI: 0.40–0.83).
Conclusion In nulliparous individuals with class III obesity, the risk of CNAO and of CMAO without transfusion were significantly lower in individuals who labored, versus those who had a planned CD.
Key Points
Synthesis of 6-Hydroxy-8-chlorooctanoate Ethyl Ester by Chemoenzymatic Method
Authors: Zhang Hongbin , Ding Zhengdong 
Published: September 2024

Abstract6-Hydroxy-8-chlorooctanoate ethyl ester, an intermediate of α-lipoic acid, was synthesized via a chemoenzymatic method. High-throughput screening revealed that keto reductase HGD-1 could effectively catalyze the preparation of 6-hydroxy-8-chlorooctanoate ethyl ester, achieving a substantial conversion rate. The reaction conditions were optimized subsequently, the parameters for the complexation reaction were established as follows: a weight of AlCl3 1.8 times that of the substrate; a reaction time of 4 h; a temperature range of 20–25 °C. The parameters for the enzyme-catalyzed reaction were as follows: a temperature range of 25–30 °C; a reaction time of 4 h; a solution pH of 6.5–7.5; a substrate concentration of 50 g/L; concentrations of keto reductase HGD-1, coenzyme glucose dehydrogenase, and nicotinamide adenine dinucleotide phosphate of 3 g/L, 4 g/L, and 0.05 g/L, respectively. Under these optimal conditions, the substrate conversion rate exceeded 95%, and 92% yield of 6-hydroxy-8-chlorooctanoate ethyl ester is obtained, suggesting a viable, eco-friendly method for synthesizing α-lipoic acid, and it provides a green process route for the industrial production of α-lipoic acid.
Rhinoplasty Training: An Innovative Learning Approach Using Chicken Breast
Authors: Freire Leila , Dolci José Eduardo Lutaif 
Published: September 2024

AbstractMastering rhinoplasty surgical techniques requires extensive learning involving theoretical studies, internships, cadaver laboratories, simulators, nonhuman models, and hands-on practice. A novel method using chicken breast simplifies skill development, offering flexibility and accessibility. Training on chicken breast allows surgeons to refine skills through various techniques and grafts. This study focuses on preservation techniques using chicken as a model. Surgical sequences simulate nasal structures using prepared chicken breasts. Documentation through media illustrates procedures from basic to advanced, using materials akin to traditional rhinoplasty but in reduced quantities. Chicken breast tissue, especially sternal cartilage, offers a suitable substrate for practicing techniques and grafting without live human or cadaveric tissue. This method provides an efficient, safe, and cost-effective approach to learning rhinoplasty.
Increment in Oncovascular Risk Factors and Psychological Distress and Unaltered Vascular Endothelial Function with Advancement of the Stages in Newly Diagnosed Patients with Primary Breast Cancer
Authors: Arora Gokul , Bobby Zachariah , Ganesan Prasanth , Sunitha V. C. , Thalapalliyil Kamila 
Published: September 2024

Abstract
Background and Aims Oncovascular risk factors are common to both cardiovascular diseases and cancer. Adipocytokines, cell adhesion molecules, and psychological distress may have roles in disease progression.
Materials and Methods Eighty subjects including healthy control and patients of different stages of newly diagnosed breast cancer were recruited. The levels of psychological distress, oncovascular risk factors, and endothelial function were estimated.
Results Soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1), adiponectin, and scores of anxiety (Generalized Anxiety Disorder-7 [GAD-7]), depression (Patient Health Questionnaire-9 [PHQ-9]), and perceived stress (Perceived Stress Scale [PSS]) increased with increasing stages of the disease. Vascular endothelial function (brachial artery flow-mediated dilation) among the different stages and healthy controls was comparable. Adiponectin (area under the curve [AUC] = 0.755 at 1.66 µg/mL, sensitivity 70% and specificity 80%), sICAM-1 (AUC = 0.769 at 264 pg/mL, sensitivity 80% and specificity 75%), and sVCAM-1 (AUC = 0.934 at 165 ng/mL, sensitivity 88% and specificity 85%) are useful in the breast cancer diagnosis with receiver operating characteristic curves. PSS (r = 0.688, p < 0.001), PHQ-9 (r = 0.633, p < 0.001), GAD-7 scores (r = 0.674, p < 0.001) and levels of sICAM-1 (r = 0.480, p < 0.001) and sVCAM-1 (r = 0.577, p < 0.00) correlated with disease progression. Perceived stress had maximum independent association with the disease progression. Oncovascular risk factors correlated with perceived stress, anxiety, and depression.
Conclusion Increment in oncovascular risk factors, psychological distress, and their associations were observed with increasing stages of breast cancer. Intervention to prevent incidence of coronary heart diseases and appropriate psychological counseling for patients with breast cancer may be considered for bringing forth better treatment outcome.
Clinical Benefit and Safety of Palbociclib in Hormone Positive Breast Cancer with Visceral Metastasis: Real-World Experience from a Tertiary Cancer Center
Authors: K. S Sandeep , Appachu Sandhya , Diwaker Ravi B. , Vivek Sai , Simha Vijai V.S. 
Published: September 2024

Abstract
Introduction Palbociclib, the first CDK4/6 inhibitor, has shown promising results in phase III clinical studies by enhancing the efficacy of endocrine therapy (ET) in HR +/HER2– advanced breast cancer. However, real-world data on its use in patients with visceral metastatic disease are limited. We aimed to assess the effectiveness and tolerability of palbociclib in this high-risk population across different lines of treatment.
Materials and Methods Patients with hormone-positive metastatic breast cancer who received palbociclib with ET between 2015 and 2021 were grouped into skeletal and visceral metastatic disease. Visceral metastatic diseases were subclassified into lung, liver, and brain metastatic diseases. All subgroups were analyzed for progression-free survival (PFS), toxicity, and prognostic factors. Subgroups were compared using the chi-square test, and survival analyses were done using the Kaplan–Meier test.
Results Among 100 patients who received palbociclib, 70 had progressed on previous ET. The common metastatic site was bone (56%), followed by lung (24%), liver (18%), and brain (2%). With a median follow-up of 37 months, the median PFS of the overall population was 24 months: bone metastasis 27 months, lung 25 months, liver 12 months, and brain 4 months. Weak hormone positivity, ET-resistant metastatic patients, and high grade were associated with poorer responses. The common side effects were neutropenia (40%), anemia (35%), thrombocytopenia (15%), and hepatotoxicity (10%). Three percent of patients discontinued treatment due to toxicity.
Conclusion Palbociclib with ET showed improved PFS and safety in visceral metastatic disease, comparable to randomized controlled trials. However, further studies are required to evaluate its efficacy in extensive visceral metastatic disease and previously heavily treated patients.
Exploring the electronic structure and lithium diffusion kinetics of amorphous tungsten oxide
Authors: Tang Chao , Liu Huachen , Cai Changlong 
Published: September 2024

Density functional theory-based characterization of crystalline tungsten oxide has been well established. Nonetheless, there remains a partial gap in theoretical studies concerning the electrochemical characterization of amorphous tungsten oxide. The electronic structure and diffusion kinetics of amorphous tungsten oxide require a systematic theoretical study. Therefore, we employed second-generation Car–Parrinello molecular dynamics simulations and the density functional theory with HSE06 exchange–correlation hybrid functional to investigate the electronic properties and lithium kinetics of amorphous tungsten oxide (α-WOx, x = 3, 2.5, 2) models. The precise electronic properties of these structures were computed using the HSE06 hybrid functions. The diffusion properties of lithium were determined in the range of 1 × 10−7 to 5 × 10−7 cm2/s by ab initio molecular dynamics. The computational findings provide a critical atomic-scale understanding and contribute to the development of tungsten oxide-based electrochromic devices for practical applications.
Average daily gain in lambs grazing mixed annual forage species compared with single species and relationship to feed on offer
Authors: Clayton E. H. , Fahey H. , Tyndall P. , Lowrie R. , Xu B. , Ataollahi F. , Norton M. R. 
Published: September 2024

Context Annual forage crops provide high-quality fodder for livestock during typical autumn and winter feed-gaps in the south-east of Australia and benefits through rotations in cropping systems. While benefits from intercropping with cereals and pasture or mixing canola and peas have been studied in Australia, the potential animal-production benefits of grazing mixed annual species forage crops have not been examined. Aims To determine average daily gain (ADG) and rumen fluid parameters when sheep graze mixtures of annual fodder crops compared with a single species. Methods Ninety six Dorset × Border Leicester × Merino lambs (mean = 44.3 ± 0.55 kg) were allocated to one of the following four treatment groups (n = 24/treatment) on the basis of sex and liveweight; a single species brassica control (canola) (Br) or annual forage species mixes containing brassica (canola, turnip, radish) and cereal (wheat, cereal rye) (B + C), brassica and legume (vetch, arrowleaf clove) (B + L) or brassica, cereal and legume (B + C + L). Liveweight and rumen fluid parameters were assessed prior to grazing and again 21 and 35 days after the commencement of grazing. Key results Mean ADG from Day 0 to Day 21 was lower for female, but not male, lambs grazing the Br control (231 ± 23 g head−1 day−1) than for those grazing any forage mix (B + C = 292 ± 23 g head−1 day−1, B + L = 296 ± 23 g head−1 day−1, B + C + L = 310 ± 22 g head−1 day−1). Liveweight change over 35 days of grazing was not different between any forage mixtures. Rumen fluid pH was higher (P < 0.001) for sheep grazing forages containing cereals (B + C = 6.97 ± 0.06, B + C + L = 6.86 ± 0.06) than for those grazing brassica or legume (Br = 6.59 ± 0.06, B + L = 6.68 ± 0.06). Total volatile fatty acid concentration was lower and rumen pH was higher when sheep grazed B + C than when they grazed any other forage mix. Conclusions The higher ADG in females grazing mixtures than in those grazing the Br was related to higher dry matter on offer. Further research should determine whether the lower pH observed when sheep grazed brassica and legume than when grazing mixes containing cereals is associated with subacute rumen acidosis and reduced fibre degradation and forage energy utilisation. Implications Mixed forage species can provide higher DM on offer and ADG. Improved rumen efficiency could be related to improved growth.
Revolutionising agriculture for food security and environmental sustainability: A perspective on the role of digital twin technology
Authors: Ametefe Divine Senanu , Hussin Norhayati , John Dah , Dzorgbenya Ametefe George , Adozuka Aliu Abdulmalik , Abdi Ali Zainab 
Published: September 2024

Abstract
The agricultural sector faces escalating challenges from climate volatility, environmental degradation, and rising food demand. Digital twin (DT) technology offers a transformative solution by creating virtual replicas of farms for data-driven decision making, optimising crop management, and enhancing soil health. This study highlights key findings on DT’s role in improving agricultural efficiency, sustainability, and resilience. Global case studies demonstrate successful DT deployment, although challenges persist in developing countries. Recommendations are provided to overcome these barriers. Ultimately, DTs are crucial for advancing sustainable farming, enhancing food security, mitigating environmental impacts, and aligning agriculture with global conservation and food security goals.
Torsional regularization of self-energy and bare mass of electron
Authors: Del Grosso Michael , Popławski Nikodem 
Published: September 2024

Abstract
In the presence of spacetime torsion, the momentum components do not commute; therefore, in quantum field theory, summation over the momentum eigenvalues will replace integration over the momentum. In the Einstein–Cartan theory of gravity, in which torsion is coupled to spin, the separation between the eigenvalues increases with the magnitude of the momentum. Consequently, this replacement regularizes divergent integrals in Feynman diagrams with loops by turning them into convergent sums. In this article, we apply torsional regularization to the self-energy of a charged lepton in quantum electrodynamics. We show that torsion eliminates the ultraviolet divergence of the standard self-energy. We also show that the infrared divergence is absent. In the end, we calculate the finite bare masses of the electron, muon, and tau lepton:

0.4329

MeV

,

90.95

MeV

, and

1543

MeV

, respectively. These values constitute about 85% of the observed, re-normalized masses.
Plasma power-to-X (PP2X): status and opportunities for non-thermal plasma technologies
Authors: Sun Jing , Qu Zhongping , Gao Yuting , Li Tianyu , Hong Jungmi , Zhang Tianqi , Zhou Rusen , Liu Dingxin , Tu Xin , Chen Guoxing , Brüser Volker , Weltmann Klaus-Dieter , Mei Danhua , Fang Zhi , Borras Ana , Barranco Angel , Xu Shaojun , Ma Chuanlong , Dou Liguang , Zhang Shuai , Shao Tao , Chen Guangliang , Liu Dawei , Lu Xinpei , Bo Zheng , Chiang Wei-Hung , Vasilev Krasimir , Keidar Michael , Nikiforov Anton , Jalili Ali Rouhollah , Cullen Patrick J , Dai Liming , Hessel Volker , Bogaerts Annemie , Murphy Anthony B , Zhou Renwu , Ostrikov Kostya (Ken) 
Published: September 2024

Abstract
This article discusses the ‘power-to-X’ (P2X) concept, highlighting the integral role of non-thermal plasma (NTP) in P2X for the eco-friendly production of chemicals and valuable fuels. NTP with unique thermally non-equilibrium characteristics, enables exotic reactions to occur under ambient conditions. This review summarizes the plasma-based P2X systems, including plasma discharges, reactor configurations, catalytic or non-catalytic processes, and modeling techniques. Especially, the potential of NTP to directly convert stable molecules including CO2, CH4 and air/N2 is critically examined. Additionally, we further present and discuss hybrid technologies that integrate NTP with photocatalysis, electrocatalysis, and biocatalysis, broadening its applications in P2X. It concludes by identifying key challenges, such as high energy consumption, and calls for the outlook in plasma catalysis and complex reaction systems to generate valuable products efficiently and sustainably, and achieve the industrial viability of the proposed plasma P2X strategy.