bluuebunny/crossref_metadata_2025_split huggingface dataset:
Micro‐Segmented Flow Technology Applied for Synthesis and Shape Control of Lead Styphnate Micro‐Particles
Authors: Zhao Shuangfei , Yan Fanyuhui , Zhu Peng , Yang Yong , Xia Huanming , Shen Ruiqi , Ye Yinghua 
Published: December 2017

AbstractIn this study, the technology of micro‐segmented flow was applied for continuous synthesis safely and shape control accurately to lead trinitroresorcinate (LTNR) particles. Besides, a micro chemical reaction and crystallization system were built. Crystal shape control technology of LTNR and micro‐segmented flow technology were first combined using the system. Additionally, the effects of the flowing rate and chemical additives on LTNR micro‐particles preparation were researched for shape control. The LTNR micro‐particles were analyzed by XRD, DSC, laser scanning confocal microscope and laser particle size analyzer. The results shows that the LTNR particles size can be controlled from 20 to 400 μm by the flow rate and the concentration of hexadecyl trimethyl ammonium bromide (CTAB), while the shape of LTNR can be controlled by the concentration of glycerol and CTAB. Besides, there is a good linear relationship between the size and the activation energy. This illustrates that the LTNR particles with smaller size are more stable and have higher heat release. This study demonstrated the power of micro‐segmented flow for generation of LTNR micro‐particles with high quality and for tuning of particle properties.
Biochips—New Platforms for Cell‐Based Immunological Assays
Authors: Shao Ning , Qin Lidong 
Published: December 2017

AbstractConsiderable advances have been witnessed in the development of biochips that seek to realize various types of immune cell analysis on microscale platforms and enhance both basic and applied immunological research beyond the capability of conventional methods. Here, state‐of‐the‐art designs and examples for biochip‐based analysis and manipulation of immune cells are reviewed, and the potential of this emerging technology to enhance the understanding of immunology and improve disease diagnosis and treatment is discussed. In particular, some of the recent advances in this field, along with the challenges that must be addressed for these technologies, and their potential in precision medicine are highlighted.
COHERENT INCURRED PAID (CIP) MODELS FOR CLAIMS RESERVING
Authors: Dupin Gilles , Koenig Emmanuel , Le Moine Pierre , Monfort Alain , Ratiarison Eric 
Published: December 2017

AbstractIn this paper, we first propose a statistical model, called the Coherent Incurred Paid model, to predict future claims, using simultaneously the information contained in incurred and paid claims. This model does not assume log-normality of the levels (or normality of the growth rates) and is semi-parametric since it only specifies the first and the second moments; however, in order to evaluate the impact of the normality assumption, we also propose a benchmark Gaussian version of our model. Correlations between growth rates of incurred and paid claims are allowed and the tail development period is estimated. We also provide methods for computing the Claim Development Results and their Values at Risk in the semi-parametric framework. Moreover, we show how to take into account the updating of the estimation in the computation of the Claim Development Results. An application highlights the practical importance of relaxing the normality assumption and of updating the estimation of the parameters.
Direct Costs of a Contact Isolation Day: A Prospective Cost Analysis at a Swiss University Hospital
Authors: Roth Jan A. , Hornung-Winter Claudia , Radicke Isabel , Hug Balthasar L. , Biedert Monika , Abshagen Christian , Battegay Manuel , Widmer Andreas F. 
Published: December 2017

We prospectively evaluated direct costs of contact precautions using on-site observation. Additional mean costs per patient day were calculated for extra materials used, increased workload, and one-off isolation activities. The cost of contact precautions was $158.90 (95% confidence interval, $124.90‒$192.80) per patient day.Infect Control Hosp Epidemiol 2018;39:101–103
The regular reflection→Mach reflection transition in unsteady flow over convex surfaces
Authors: Geva M. , Ram O. , Sadot O. 
Published: December 2017

The non-stationary transition from regular reflection (RR) to Mach reflection (MR) over convex segments has been the focus of many recent studies. Until recently, the problem was thought to be very complicated because it was believed that many parameters such as the radius of curvature, initial angle and geometrical shape of the reflecting surface influenced this process. In this study, experiments and inviscid numerical computations were performed in air ($\unicode[STIX]{x1D6FE}=1.4$) at an incident shock-wave Mach number of 1.3. The incident shock waves were reflected over cylindrical and elliptical convex surfaces. The computations were validated by high-resolution experiments, which enabled the detection of features in the flow having characteristic lengths as small as 0.06 mm. Therefore, the RR →MR transition and Mach stem growth were successfully validated in the early stages of the Mach stem formation and closer to the surface than ever before. The evolution of the RR, the transition to MR and the Mach stem growth were found to depend only on the radius of the reflecting surface. The reflected shock wave adjusts itself to the changing angles of the reflecting surface. This feature, which was demonstrated at Mach numbers 1.3 and 1.5, distinguishes the unsteady case from the self-similar pseudo-steady case and requires the formulation of the conservation equations. A modification of the standard two-shock theory (2ST) is presented to predict the flow properties behind a shock wave that propagates over convex surfaces. Until recently, the determination of the time-dependent flow properties was possible solely by numerical computations. Moreover, this derivation explains the controversial issue on the delay in the transition from the RR to the MR that was observed by many researchers. It turns out that the entire RR evolution and the particular moment of transition to MR, are based on the essential ‘no-penetration’ condition of the flow. Therefore, we proposed a simple geometrical criterion for the RR →MR transition.
The Law of One Price? Price Dispersion on the Auction Market for Fine Wine
Authors: Cardebat Jean-Marie , Faye Benoît , Le Fur Eric , Storchmann Karl 
Published: December 2017

AbstractThis paper examines the strong version of the law of one price (LOOP) on the auction market for fine wine. We draw on worldwide auction prices from eight auction houses,1covering the time period from 2000 to 2012. Employing a hedonic approach, we find significant price premiums in particular in Hong Kong and between auction companies (independent of their locations). The price premiums by far exceed the expected transaction costs, casting doubt on the existence of the strong version of LOOP in the fine wine market. Our results suggest that heterogeneity in buyer preferences may crucially contribute to the observed price dispersion. In particular, although wines suspected of being counterfeits are sold at discounts in Western markets, they fetch price premiums in Hong Kong. (JEL Classifications: Q14, G11)
THE PECULIARITIES OF GERMAN PHILHELLENISM
Authors: ROCHE HELEN 
Published: December 2017

AbstractStudies of German philhellenism have often focused upon the idealization of Greece by German intellectuals, rather than considering the very real, at times reciprocal, at times ambivalent or even brutal, relationship which existed between contemporary Germans and the Greek state from the Greek War of Independence onwards. This review essay surveys historiographical developments in the literature on German philhellenism which have emerged in the past dozen years (2004–16), drawing on research in German studies, classical philology and reception studies, Modern Greek studies, intellectual history, philosophy, art history, and archaeology. The essay explores the extent to which recent research affirms or rebuts that notion of German cultural exceptionalism which posits a HellenophileSonderweg– culminating in the tyranny of Germany over Greece imposed by force of arms under the Third Reich – when interpreting the vicissitudes of the Graeco–German relationship. The discussion of new literature touches upon various themes, including Winckelmann reception at the fin-de-siècle and the anti-positivist aspects of twentieth-century philhellenism, the idealization of ‘Platonic’ homoeroticism in the Stefan George-Kreis, the reciprocal relationship between German idealist philhellenism and historicism, and the ways in which German perceptions of modern Greece's materiality have constantly been mediated through idealized visions of Greek antiquity.
Ancient multiple-layer solutions to the Allen–Cahn equation
Authors: Pino Manuel del , Gkikas Konstantinos T. 
Published: December 2017

We consider the parabolic one-dimensional Allen–Cahn equationThe steady state connects, as a ‘transition layer’, the stable phases –1 and +1. We construct a solution u with any given number k of transition layers between –1 and +1. Mainly they consist of k time-travelling copies of w, with each interface diverging as t → –∞. More precisely, we findwhere the functions ξj (t) satisfy a first-order Toda-type system. They are given byfor certain explicit constants γjk.
Costs of delivery approaches for providing livelihood projects to local communities as part of REDD+ programmes: An analysis from Madagascar
Authors: MACKINNON JAMES L. , ANDRIAMARO LUCIANO , RAMBELOSON ANDONIAINA , RAZAFINDRAZAKASOA MIALY , HARVEY CELIA A. 
Published: December 2017

SUMMARYProviding benefits to local people from forest conservation programmes is an important issue for policy makers. Livelihood projects are a common way to provide benefits, but there is little information about their costs. We analysed 463 livelihood projects in the Ankeniheny-Zahamena Corridor Reducing Emissions from Deforestation and Degradation (REDD+) pilot project in Madagascar to understand how different approaches to delivering livelihood projects affect costs. We compared costs across four approaches: conservation agreements, small grants, direct implementation and application of social safeguards. The approach impacted overall costs and the proportion of funds reaching communities. Projects implemented as safeguards were most expensive and had the lowest proportion of expenditures reaching the community. Projects provided as part of conservation agreements directed the highest proportion of expenditures to communities. Our results highlight that how livelihood projects are delivered has implications for project costs and community benefits and should be an important consideration in the design and implementation of REDD+ and forest conservation policies.
The Limits of Presidential Influence: Two Environmental Directives and What They Mean for Executive Power
Authors: Kennedy Joshua B. 
Published: December 2017

Abstract:The executive order process can be a long and complicated one, as directives may wind their way through various agencies before finding their way onto the president’s desk. Even after these orders have been issued, federal agencies will have a wide degree of latitude under certain conditions as it pertains to implementing them. In this article, I study the history of three separate presidential directives, two dealing specifically with environmental issues and one with general regulatory issues, in order to provide a picture of the process from inception to implementation. I consider three cases and explore the factors that drive presidents in choosing when or whether to issue an order and those that drive federal agencies to react as they do. This article encourages scholars to reconsider what they consider “unilateral,” pointing to the instances in which presidents must engage in bargaining within the executive branch they ostensibly head.
Robust Tverberg and Colourful Carathéodory Results via Random Choice
Authors: SOBERÓN PABLO 
Published: December 2017

We use the probabilistic method to obtain versions of the colourful Carathéodory theorem and Tverberg's theorem with tolerance.In particular, we give bounds for the smallest integer N = N(t,d,r) such that for any N points in ℝd, there is a partition of them into r parts for which the following condition holds: after removing any t points from the set, the convex hulls of what is left in each part intersect.We prove a bound N = rt + O($\sqrt{t}$) for fixed r,d which is polynomial in each parameters. Our bounds extend to colourful versions of Tverberg's theorem, as well as Reay-type variations of this theorem.
Vitrification of bovine embryos followed by in vitro hatching and expansion
Authors: Souza J.F. , Oliveira C.M. , Lienou L.L. , Cavalcante T.V. , Alexandrino E. , Santos R.R. , Rodrigues A.P.R. , Campello C.C. , Figueiredo J.R. , Dias F.E.F. 
Published: December 2017

SummaryThe objective of this study was to assess the effects of bovine embryo vitrification by applying three different vitrification solutions containing ethylene glycol (EG) and dimethylsulphoxide (DMSO) at different concentrations (10, 20 or 25% each) combined with 1.0 M glucose or 1.0 M sucrose, on the in vitro hatching and expansion rates. Healthy oocytes were selected for in vitro maturation and fertilization from 200 bovine ovaries, and subsequently cultured up to the blastocyst stage (n = 800). Control (n = 200) and vitrified cells (n = 100 per treatment; 600 in total) were cultured for an extra 24 or 48 h to evaluate hatching and expansion, respectively. Vitrification significantly decreased embryonic re-expansion and hatching rates independently of the tested solution when compared with control embryos, but solutions with 25% EG + 25% DMSO resulted in the highest re-expansion (75%) and hatching (70%) rates, independently of the added sugar. The addition of sucrose resulted in higher rates of re-expanded and hatched embryos when compared with glucose addition. We concluded that the combination of 25% EG + 25% DMSO and 1.0 M sucrose allowed hatching and expansion of vitrified-warmed bovine embryos produced in vitro.
Health Outcomes for Children in Haiti Since the 2010 Earthquake: A Systematic Review
Authors: Dube Annie , Moffatt Madeline , Davison Colleen , Bartels Susan 
Published: December 2017

AbstractBackgroundHaiti remains the poorest country in the Americas and one of the poorest in the world. Children in Haiti face many health concerns, some of which were exacerbated by the 2010 earthquake. This systematic review summarizes published research conducted since the 2010 earthquake, focusing on health outcomes for children in Haiti, including physical, psychological, and socioeconomic well-being.MethodsA literature search was conducted identifying articles published from January 2010 through May 2016 related to pediatric health outcomes in Haiti. Two reviewers screened articles independently. Included research articles described at least one physical health, psychological health, or socioeconomic outcome among children less than 18 years of age in Haiti since the January 2010 earthquake.ResultsFifty-eight full-length research articles were reviewed, covering infectious diseases (non-cholera [N=12] and cholera [N=7]), nutrition (N=11), traumatic injuries (N=11), mental health (N=9), anemia (N=4), abuse and violence (N=5), and other topics (N=3). Many children were injured in the 2010 earthquake, and care of their injuries is described in the literature. Infectious diseases were a significant cause of morbidity and mortality among children following the earthquake, with cholera being one of the most important etiologies. The literature also revealed that large numbers of children in Haiti have significant symptoms of posttraumatic stress disorder (PTSD), peri-traumatic stress, depression, and anxiety, and that food insecurity and malnutrition continue to be important issues.ConclusionsFuture health programs in Haiti should focus on provision of clean water, sanitation, and other measures to prevent infectious diseases. Mental health programming and services for children also appear to be greatly needed, and food insecurity/malnutrition must be addressed if children are to lead healthy, productive lives. Given the burden of injury after the 2010 earthquake, further research on long-term disabilities among children in Haiti is needed.DubeA,MoffattM,DavisonC,BartelsS.Health outcomes for children in Haiti since the 2010 earthquake: a systematic review.Prehosp Disaster Med.2018;33(1):77–88.
Projection models for health expenses
Authors: Christiansen Marcus , Denuit Michel , Lucas Nathalie , Schmidt Jan-Philipp 
Published: December 2017

AbstractThis note proposes a practical way for modelling and projecting health insurance expenditures over short time horizons, based on observed historical data. The present study is motivated by a similar age structure generally observed for health insurance claim frequencies and yearly aggregate losses on the one hand and mortality on the other hand. As an application, the approach is illustrated for German historical inpatient costs provided by the Federal Financial Supervisory Authority. In particular, similarities and differences to mortality modelling are addressed.
The oldest representative of the family Austropanorpidae (Mecoptera) from the Lower Jurassic of Siberia
Authors: Krzemiński Wiesław , Soszyńska-Maj Agnieszka , Kopeć Katarzyna , Sukatsheva Irena D. 
Published: December 2017

ABSTRACTThe family Austropanorpidae (Mecoptera) was described by Willmann in 1977 from the Eocene of Australia, based on one genus and species, Austropanorpa australis Riek, 1952. During a restudy of the collection of the Paleontological Institute, Russian Academy of Sciences in Moscow, a second and much older representative of this family was found. This specimen, described as Orthophlebia martynovae Sukatsheva, 1985 from Siberia (Russia), was considered until now to be a member of family Orthophlebiidae. We transfer this species to the Austropanorpidae, extending the age of this family back to the Early Jurassic. An updated diagnoses of the family Austropanorpidae and genus Austropanorpa are presented here.
Prediction of aesthetic reconstruction effects in edentulous patients
Authors: Yuan Fusong , Cheng Cheng , Dai Ning , Sun Yuchun 
Published: December 2017

AbstractThe aim of the study is to establish a virtual prediction method to predict aesthetic reconstruction effects in edentulous patients. The facial soft tissue surface data before and after wearing complete dentures of ten edentulous patients were acquired with a facial Three-dimension scanner. Then, the two sets of scanned data were entered into the same coordinate system. Manual interaction was performed to extract the external boundary of the perioral appearance deformation area, and the proportional relationships of key facial anatomical features were measured. A virtual prediction software module was developed based on back-propagation neural networks and a Laplacian deformation algorithm. Virtual prediction of the aesthetic reconstruction effects in the overall appearance of the lower third of the face was performed in 10 edentulous patients. The mean accuracy of the virtual predictions was approximately 0.769 ± 0.205 mm, and there were statistically significant differences between the 10 patients (p < 0.05). The scope of the changes in facial appearance of edentulous patients was smaller than the scope of the lower third of the face. This method can achieve the virtual prediction of soft tissue appearance in the lower third of the face after wearing complete dentures to an extent.
Knockdown of long non-coding RNA H19 inhibits multiple myeloma cell growth via NF-κB pathway
Authors: Sun Yuanyuan , Pan Jing , Zhang Ning , Wei Wei , Yu Shanshan , Ai Limei 
Published: December 2017

AbstractLong non-coding RNAs (lncRNAs) are implicated in the complex network of cancer including Multiple myeloma (MM) and play important roles in tumor development. lncH19 was significantly up-regulated in multiple cancer types, suggesting it is a potential oncogene. However, the exact functions and downstream mechanisms are largely unknown. This study aimed to investigate whether H19 participates in the cell growth of MM and elucidate the underlying mechanism. We found that H19 was abnormally overexpressed in MM cell lines and sorted CD138+ MM bone marrow tissues. H19 knockdown induced by shRNA transfection significantly inhibited proliferation, viability and colony formation in MM cells, as well as inactivated NF-κB pathway. Moreover, combination treatment of H19 knockdown and NF-κB suppression (induced by specific inhibitor PDTC) produced synergistically inhibitory effects. Bone marrow expression of H19 was positively associated with circulating IL-6 or IL-8 level in the same MM patients. And patients with high expression of H19 had a lower survival rate. Taken together, we confirmed the abnormal upregulation of a novel lncRNA, H19, in human MM. H19 was involved in MM cell growth. The linkage between H19 and NF-κB pathway may provide a novel interpretation for the mechanism of H19’s growth regulation in MM.
The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis
Authors: Ogata Kayoko , Tsumuraya Tomoyuki , Oka Kyoko , Shin Masashi , Okamoto Fujio , Kajiya Hiroshi , Katagiri Chiaki , Ozaki Masao , Matsushita Masayuki , Okabe Koji 
Published: December 2017

AbstractTransient receptor potential melastatin-7 (TRPM7) is a bi-functional protein containing a kinase domain fused to an ion channel. TRPM7 is highly expressed in ameloblasts during tooth development. Here we show that TRPM7 kinase-inactive knock-in mutant mice (TRPM7 KR mice) exhibited small enamel volume with opaque white-colored incisors. The TRPM7 channel function of ameloblast-lineage cells from TRPM7 KR mice was normal. Interestingly, phosphorylation of intracellular molecules including Smad1/5/9, p38 and cAMP response element binding protein (CREB) was inhibited in ameloblasts from TRPM7 KR mice at the pre-secretory stage. An immunoprecipitation assay showed that CREB was bound to TRPM7, suggesting that direct phosphorylation of CREB by TRPM7 was inhibited in ameloblast-lineage cells from TRPM7 KR mice. These results indicate that the function of the TRPM7 kinase domain plays an important role in ameloblast differentiation, independent of TRPM7 channel activity, via phosphorylation of CREB.
Discovery of novel solid solution Ca3Si3−x
O3+x
N4−2x
: Eu2+ phosphors: structural evolution and photoluminescence tuning
Authors: Wang Baochen , Liu Yan-gai , Huang Zhaohui , Fang Minghao , Wu Xiaowen 
Published: December 2017

AbstractDiscovery of novel phosphors is one of the main issues for improving the color rendering index (CRI) and correlated color temperature (CCT) of white light-emitting diodes (w-LEDs). This study mainly presents a systematic research on the synthesis, crystal structure variation and photoluminescence tuning of novel (oxy)nitride solid solution Ca3Si3−x
O3+x
N4−2x
: Eu2+ phosphors. XRD refinements show that lattice distortion occurs when x value diverges the optimum one (x = 1). The lattice distortion causes a widening of emission spectrum and an increase of Stokes shift (ΔSS), which leads to a bigger thermal quenching. With decrease of x value, the emission spectrum shows an obvious red-shift from 505.2 to 540.8 nm, which is attributed to the crystal field splitting. The enhanced crystal field splitting also broadens the excitation spectrum, making it possible to serve as the phosphor for near ultraviolet (n-UV) LEDs. A 3-phosphor-conversion w-LED lamp was fabricated with the as-prepared phosphor, which exhibits high CRI (Ra = 85.29) and suitable CCT (4903.35 K). All these results indicate that the Ca3Si3−x
O3+x
N4−2x
: Eu2+ phosphor can serve as the green phosphor for n-UV w-LEDs, with a tunable spectrum by controlling the crystal structure and morphology.