bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socialist and Revisionist Zionisms, 1917–1939
Authors: Stanislawski Michael 
Published: April 2017

Abstract
Britain gained control over Palestine in the “mandate” system created by the League of Nations after the debacle of the World War I. “Socialist and revisionist Zionisms, 1917–1937” outlines the rise in Palestine of the socialist Zionist parties—both the Marxist Zionists and the Utopian Zionists—and their virtual monopoly over the basic institutions of the Jewish community in Palestine. It also describes the right-wing Revisionist Zionism and its founder, Vladimir Jabotinsky. The reversal of British policy on Palestine and its proposal for the partition of the country into Jewish and Arab states was met with opposition by most of the Zionist groups, as well as the Palestinian nationalist movement.
Transformations of Zionism since 1995
Authors: Stanislawski Michael 
Published: April 2017

Abstract
For a short while after Rabin’s death, right-wing politicians and religious leaders became less inflammatory, but soon Israeli politics returned to normal. The swing from left to right repeated time and time again: parties on the left, the middle, and the right have been riven by splits into smaller parties, which therefore inevitably hold the balance of power, while the country as a whole is split down the middle on domestic and foreign policies. “Transformations of Zionism since 1995” tracks the results of recent elections, notes the importance of the huge increase in immigrants from the Soviet Union, describes the modernization of the Israeli economy, and highlights the dramatic rebirth of Orthodox Zionism.
A scalable moment-closure approximation for large-scale biochemical reaction networks
Authors: Kazeroonian Atefeh , Theis Fabian J , Hasenauer Jan 
Published: April 2017

Abstract

Motivation
Stochastic molecular processes are a leading cause of cell-to-cell variability. Their dynamics are often described by continuous-time discrete-state Markov chains and simulated using stochastic simulation algorithms. As these stochastic simulations are computationally demanding, ordinary differential equation models for the dynamics of the statistical moments have been developed. The number of state variables of these approximating models, however, grows at least quadratically with the number of biochemical species. This limits their application to small- and medium-sized processes.

Results
In this article, we present a scalable moment-closure approximation (sMA) for the simulation of statistical moments of large-scale stochastic processes. The sMA exploits the structure of the biochemical reaction network to reduce the covariance matrix. We prove that sMA yields approximating models whose number of state variables depends predominantly on local properties, i.e. the average node degree of the reaction network, instead of the overall network size. The resulting complexity reduction is assessed by studying a range of medium- and large-scale biochemical reaction networks. To evaluate the approximation accuracy and the improvement in computational efficiency, we study models for JAK2/STAT5 signalling and NFκB signalling. Our method is applicable to generic biochemical reaction networks and we provide an implementation, including an SBML interface, which renders the sMA easily accessible.

Availability and implementation
The sMA is implemented in the open-source MATLAB toolbox CERENA and is available from https://github.com/CERENADevelopers/CERENA.

Supplementary information
Supplementary data are available at Bioinformatics online.
Growth Differentiation Factor 5 Accelerates Wound Closure and Improves Skin Quality During Repair of Full-Thickness Skin Defects
Authors: Schiefer Jennifer L. , Held Manuel , Fuchs Paul C. , Demir Erhan , Plöger Frank , Schaller Hans-Eberhard , Rahmanian-Schwarz Afshin 
Published: April 2017

ABSTRACT

BACKGROUND:
A fast and stable wound closure is important, especially for extended and unstable wounds found after burn injuries. Growth can regulate a variety of cellular processes, including those involved in wound healing. Growth differentiation factor 5 (GDF-5) can accelerate fibroblast cell migration, cell proliferation, and collagen synthesis, which are essential for wound healing. Nevertheless, no standardized evaluation of the effect of GDF-5 on the healing of full-thickness wounds has been published to date.

METHODS:
Five full-thickness skin defects were created on the backs of 6 minipigs. Three wounds were treated with GDF-5 in different concentrations with the help of a gelatin-collagen carrier, and 2 wounds served as control group. The first was treated with the gelatin carrier and an Opsite film (Smith & Nephew, Fort Worth, Texas), and the other was treated solely with an Opsite film that was placed above all wounds and renewed every second day.

RESULTS:
Growth differentiation factor 5 accelerates wound closure (10.91 [SD, 0.99] days) compared with treatment with the carrier alone (11.3 [SD, 1.49] days) and control wounds (13.3 [SD, 0.94] days). Epidermal cell count of wounds treated with GDF-5 revealed a higher number of cells compared with the control group. In addition, mean epidermal thickness was significantly increased in GDF-5–treated wounds compared with the control wounds.

CONCLUSIONS:
Because of its ability to improve skin quality, GDF-5 should be considered when developing composite biomaterials for wound healing.
Sodium Tetradecyl Sulfate: A Review of Clinical Uses
Authors: Jenkinson Helena A. , Wilmas Kelly M. , Silapunt Sirunya 
Published: April 2017

BACKGROUND
Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have been reported.

OBJECTIVE
To describe the clinical uses of STS, as well as efficacy and adverse effects.

METHODS
Review of studies searchable on PubMed from 1938 to 2016 describing clinical uses of STS to determine efficacy and adverse effects associated with various applications.

RESULTS
Sodium tetradecyl sulfate has shown efficacy in the treatment of varicose veins, telangiectasias, hemangioma, pyogenic granuloma, cherry angioma, Kaposi sarcoma, lymphangioma circumscriptum, digital mucous cyst, ganglion cyst, glomangioma, angiokeratoma of Fordyce, pseudocyst of the auricle, and verruca. Commonly reported side effects include pain, erythema, swelling, hyperpigmentation, telangiectatic matting, and ulceration. Serious side effects such as anaphylaxis, pulmonary embolism, stroke, and myocardial infarction have also been reported. Most sources were case reports and small prospective studies, as such the strength of data supporting many uses is limited by small sample sizes and lack of controls.

CONCLUSION
Although not always the most effective method of treatment in off-label usage, use of STS has been frequently selected for a variety of applications for reasons of simplicity, low cost, lack of availability of technologically advanced equipment, and intricacies related to anatomic location.
A multi-model approach to assessing local and global cryo-EM map quality
Authors: Herzik Mark A. , Fraser James S. , Lander Gabriel C. 
Published: April 2017

AbstractThere does not currently exist a standardized indicator of how well a cryo-EM-derived model represents the density from which it was generated. We present a straightforward methodology that utilizes freely available tools to generate a suite of independent models and to evaluate their convergence in an EM density. These analyses provide both a quantitative and qualitative assessment of the precision of the models and their representation of the density, respectively, while concurrently providing a platform for assessing both global and local EM map quality. We further use standardized datasets to provide an expected model–model agreement criterion for EM maps reported to be at 5 Å resolution or better. Associating multiple atomic models with a deposited EM map provides a rapid and accessible reporter of convergence, a strong indicator of highly resolved molecular detail, and is an important step toward an FSC-independent assessment of map and model quality.
On statistical modeling of sequencing noise in high depth data to assess tumor evolution
Authors: Rabadan Raul , Bhanot Gyan , Marsilio Sonia , Chiorazzi Nicholas , Pasqualucci Laura , Khiabanian Hossein 
Published: April 2017

AbstractOne cause of cancer mortality is tumor evolution to therapy-resistant disease. First line therapy often targets the dominant clone, and drug resistance can emerges from preexisting clones that gain fitness through therapy-induced natural selection. Such mutations may be identified using targeted sequencing assays by analysis of noise in high-depth data. Here, we develop a comprehensive, unbiased model for sequencing error background. We find that noise in sufficiently deep DNA sequencing data can be approximated by aggregating negative binomial distributions. Mutations with frequencies above noise may have prognostic value. We evaluate our model with simulated exponentially expanded populations as well as data from cell line and patient sample dilution experiments, demonstrating its utility in prognosticating tumor progression. Our results may have the potential to identify significant mutations that can cause recurrence. These results are relevant in the pretreatment clinical setting to determine appropriate therapy and prepare for potential recurrence pretreatment.
Characterisation of Trichuris muris secreted proteins and extracellular vesicles provides new insights into host-parasite communication
Authors: Eichenberger Ramon M. , Talukder Md Hasanuzzaman , Field Matthew A. , Wangchuk Phurpa , Giacomin Paul , Loukas Alex , Sotillo Javier 
Published: April 2017

AbstractWhipworms are parasitic nematodes that live in the gut of more than 500 million people worldwide. Due to the difficulty in obtaining parasite material, the mouse whipworm Trichuris muris has been extensively used as a model to study human whipworm infections. These nematodes secrete a multitude of compounds that interact with host tissues where they orchestrate a parasitic existence. Herein we provide the first comprehensive characterisation of the excretory/secretory products of T. muris. We identify 148 proteins secreted by T. muris and show for the first time that the mouse whipworm secretes exosome-like extracellular vesicles (EVs) that can interact with host cells. We use an Optiprep® gradient to purify the EVs, highlighting the suitability of this method for purifying EVs secreted by a parasitic nematode. We also characterise the proteomic and genomic content of the EVs, identifying >350 proteins, 56 miRNAs (22 novel) and 475 full-length mRNA transcripts mapping to T. muris gene models. Many of the miRNAs putatively mapped to mouse genes involved in regulation of inflammation, implying a role in parasite-driven immunomodulation. In addition, for the first time to our knowledge, we use colonic organoids to demonstrate the internalisation of parasite EVs by host cells. Understanding how parasites interact with their host is crucial to develop new control measures. This first characterisation of the proteins and EVs secreted by T. muris provides important information on whipworm-host communication and forms the basis for future studies.
Risk and teenage parenthood: an early sexual health intervention
Authors: Robinson Sally , Robinson Carol 
Published: April 2017

Purpose
The purpose of this paper is to outline the development of a resource designed to support practitioners, who are not sexual health specialists, but who work with young people who may be at risk of teenage pregnancy or parenthood. Its aim was to enable practitioners to carry out an assessment using a screening tool, and to use educational interventions designed to reduce risk-taking behaviour or refer to a sexual health specialist. A research project to examine the perceptions of practitioners who had used the resource is reported.

Design/methodology/approach
The resource was based on a local needs assessment and developed by a multi-agency working group. The research utilised an online questionnaire and telephone interviews with practitioners.

Findings
Practitioners reported using the screening tool with young people with an average age of 13.1 years. They thought the educational interventions provided knowledge and helped with communication, self-awareness, reflection, confidence, attitudes and values clarification.

Research limitations/implications
The project was based in one county in England. A sample of 17 per cent of the practitioners responded to the questionnaire, and they might be biased towards those who had engaged most, or most positively, with the resource. Three practitioners undertook interviews. The views and behaviours of young people are yet to be evaluated.

Originality/value
Within a climate of limited resources, the findings suggest that the project is providing an acceptable proportionate universalist, early sexual health intervention for young people.
The moderating role of social media usage in the relationship among multicultural experiences, cultural intelligence, and individual creativity
Authors: Hu Shangui , Gu Jibao , Liu Hefu , Huang Qian 
Published: April 2017

Purpose
The purpose of this paper is to explore the moderating role of social media usage in the relationship among multicultural experiences, cultural intelligence, and creativity.

Design/methodology/approach
This study conducted a questionnaire survey in three public universities in China and obtained 310 useful responses from international students.

Findings
The authors categorized social media usage into informational and socializing usage. Findings show that socializing social media usage strengthens the relationship between multicultural experiences and cultural intelligence, whereas informational social media usage does not strengthen such relationship.

Research limitations/implications
The findings suggest that practitioners, such as managers or university administrators, should focus on well-designed multicultural activities in the development of individual creativity. They should also acknowledge the enabling role of cultural intelligence in developing individual creativity and realize that social media usage should be differentiated from the outcomes of its usage.

Originality/value
This study contributes to the knowledge on the moderating role of social media usage in the relationship between multicultural experiences and creativity based on experiential learning theory. The study presents the relationship among multicultural experiences, cultural intelligence, and creativity. Moreover, by investigating the moderating roles of informational and socializing social media usage, the authors presented that an IT contingent view of multicultural experiences is helpful in understanding the relationship between multicultural experiences and cultural intelligence.
The information ethics perception gaps between Chinese and American students
Authors: Chang Christina Ling-hsing , Chen Jim Q. 
Published: April 2017

PurposeThe purpose of this paper is to understand the impact of Chinese culture on the information ethics perception gaps between Chinese and American students.Design/methodology/approachUsing a qualitative approach, this study utilizes Kohlberg’s Cognitive Moral Development model and an open-ended questionnaire to measure and analyze the gaps among information ethics perceptions of students from Taiwan, Mainland China, Hong Kong, and the USA, and to assess the extent to which the gaps are influenced by Chinese culture.FindingsStudents’ perceptions of intellectual property, information accuracy, privacy, and accessibility (PAPA) are deeply influenced by national culture. Sub-cultures have significant impact on the perceptions. Political systems, history, and legal environment may also play a role in the differences of PAPA perceptions among the three Chinese societies. The study also revealed that accuracy and intellectual property are the most deficient areas of moral developments in both Chinese and American samples.Research limitations/implicationsThe sample sizes from Hong Kong and the USA were relatively small due to resource and time constraints. In addition, the subjects from Hong Kong and the USA were a little bit older than the subjects from Taiwan and Mainland China due to the fact that universities in HK and USA tend to have more non-traditional students than in universities in Mainland China and Taiwan. Second, the questionnaire is a limited means of studying moral reasoning because the results are likely to reflect espoused theory rather than theory-in-use.Practical implicationsThe educational implication of this study calls for a renewed approach to educate students on the importance of information ethics for the sake of sustained economic development.Originality/valueThe novelty of this research lies in its interpretation of students’ PAPA perceptions and fresh insights from a Chineseguanxiperspective.
How does accreditation influence staff perceptions of quality in residential aged care?
Authors: Hogden Anne , Greenfield David , Brandon Mark , Debono Deborah , Mumford Virginia , Westbrook Johanna , Braithwaite Jeffrey 
Published: April 2017

PurposeQuality of care in the residential aged sector has changed over the past decade. The purpose of this paper is to examine these changes from the perspectives of staff to identify factors influencing quality of residential aged care, and the role and influence of an aged care accreditation programme.Design/methodology/approachFocus groups were held with 66 aged care staff from 11 Australian aged care facilities. Data from semi-structured interviews were analysed to capture categories representing participant views.FindingsParticipants reported two factors stimulating change: developments in the aged care regulatory and policy framework, and rising consumer expectations. Four corresponding effects on service quality were identified: increasing complexity of resident care, renewed built environments of aged care facilities, growing focus on resident-centred care and the influence of accreditation on resident quality of life. The accreditation programme was viewed as maintaining minimum standards of quality throughout regulatory and social change, yet was considered to lack capacity of itself to explicitly promote or improve resident quality of life.Research limitations/implicationsFor an increasingly complex aged care population, regulatory and societal change has led to a shift in service provision from institutional care models to one that is becoming more responsive to consumer expectations. The capacity of long-established and relatively static accreditation standards to better accommodate changing consumer needs comes into question.Originality/valueThis is the first study to examine the relationship between accreditation and residential aged care service quality from the perspectives of staff, and offers a nuanced view of “quality” in this setting.
The “celebrities” in finance: a citation analysis of finance journals
Authors: Calma Angelito 
Published: April 2017

Purpose
The purpose of this paper is to examine the ten highly ranked journals in finance, and identify the most published authors, most cited articles, top publishing countries, top publishing universities, top publication years and the most discussed topics using keywords.

Design/methodology/approach
Using the services of the Web of Science™ (WoS), all the available data about each journal’s published articles were extracted. A total of 6,029 articles containing 23,521 keywords and 208,905 cited references were analysed.

Findings
Results indicate that Viscusi, Chemmanur and Statman are the most published authors. The most cited article is Fama and French’s (1993) article – Common risk factors in the returns on stocks and bonds – with 522 citations. The most cited author is Eugene Fama with 2,848 citations followed by Michael Jensen with 1,367 citations. USA and England contributed more articles than any other country, where US University of California System ranked first. “Information”, “risk” and “market” were the most discussed topics. Findings from this study reveal not only the popular authors, articles and topics in the scholarly finance literature, but also the lesser-known areas of research, which may need attention.

Originality/value
It is the first large-scale citation analysis study of its kind, representing data from 178 years of combined publication history.
Misreporting, Optimal Incentives, and Auditing
Authors: Loyola Gino , Portilla Yolanda 
Published: April 2017

AbstractWe propose a model that rationalizes the adoption of a misreporting system allowing managerial earning manipulation. A key element of our approach is the possibility of a tacit collusion between the board and the top management at the expense of shareholders and outside investors. Our framework predicts that the adoption of a misreporting system is mainly related to (i) the cost to the management of implementing such a system, (ii) the level of incentives and punishment the board faces, and (iii) the degree of independence/integrity of external auditors.
Are The Statue and The Clay Mutual Parts?
Authors: Walters Lee 
Published: April 2017

AbstractAre a material object, such as a statue, and its constituting matter, the clay, parts of one another? One wouldn't have thought so, and yet a number of philosophers have argued that they are. I review the arguments for this surprising claim showing how they all fail. I then consider two arguments against the view concluding that there are both pre‐theoretical and theoretical considerations for denying that the statue and the clay are mutual parts.