bluuebunny/crossref_metadata_2025_split huggingface dataset:
Highly Dispersed ZnO Sites in a ZnO/ZrO2 Catalyst Promote Carbon Dioxide‐to‐Methanol Conversion
Authors: Zhang Xibo , Yu Xiang , Mendes Rafael G. , Matvija Peter , Melcherts Angela E. M. , Sun Chunning , Ye Xinwei , Weckhuysen Bert M. , Monai Matteo 
Published: October 2024

AbstractZnO/ZrO2 catalysts have shown better activity in the CO2 hydrogenation to methanol compared with single component counterparts, but the interaction between ZnO and ZrO2 is still poorly understood. In particular, the effect of the ZrO2 support phase (tetragonal vs. monoclinic) was not systematically explored. Here, we have synthesized ZnO/ZrO2 catalysts supported on tetragonal ZrO2 (ZnO/ZrO2‐t) and monoclinic ZrO2 (ZnO/ZrO2‐m), which resulted in the formation of different ZnOx species, consisting of sub‐nanometer ZnO moieties and large‐sized ZnO particles, respectively. ZnO/ZrO2‐t exhibited a higher methanol selectivity (81 vs. 39 %) and methanol yield (1.25 vs. 0.67 mmol g−1 h−1) compared with ZnO/ZrO2‐m. The difference in performance was attributed to the redox state and degree of dispersion of Zn, based on spectroscopy and microscopy results. ZnO/ZrO2‐t had a high density of ZnOx‐ZrOy sites, which favored the formation of active HCOO* species and enhanced the yield and selectivity of methanol along the formate pathway. Such ZnO clusters were further dispersed on ZrO2‐t during catalysis, while larger ZnO particles on ZnO/ZrO2‐m remained stable throughout the reaction. This study shows that the phase of ZrO2 supports can be used to control the dispersion of ZnO and the catalyst surface chemistry, and lead to enhanced catalytic performance.
Silylene [PSiP] Pincer Cobalt(II) Chloride–Catalyzed Alkene Hydrosilylation
Authors: Dong Yanhong , Zhang Min , Li Xiaoyan , Sun Hongjian 
Published: October 2024

ABSTRACTSilylene metal complexes exhibit excellent catalytic activity and selectivity in homogeneous catalysis. However, there are relatively few examples of silylene metal complexes as catalysts for the hydrosilylation of alkenes. In order to study the effect of a silylene ligand on the catalytic performance of [PSiP] pincer Co(II) chloride for alkene hydrosilylation, the PMe3 ligand in (MeSi(C6H4‐PPh2)2)Co (PMe3)Cl (1) was replaced by a silylene ligand, and a silylene [PSiP] pincer Co(II) chloride, (MeSi(C6H4‐PPh2)2)Co (PhC (NtBu)2Si)Cl (2), was used as catalyst to study its catalytic activity in alkene hydrosilylation. It was confirmed that silylene Complex 2 has excellent catalytic activity for alkene hydrosilylation with Ph2SiH2 as a hydrogen source. For alkene hydrosilylation, compared to phosphine Complex 1, silylene Complex 2 does not need NaBHEt3 as an additive. In addition, for aromatic alkenes, silylene Complex 2 has anti‐Markovnikov selectivity, while phosphine Complex 1 provides Markovnikov products in the presence of NaBHEt3.
Evaluation of the safety of PD‐1/PD‐L1 inhibitors for immunotherapy in patients with malignant tumors after COVID‐19 infection: A single‐center cohort study
Authors: Liao Kaili , Cheng Jinting , Hu Yujie , Zhang Beining , Huang Peng , Liu Jie , Zhang Wenyige , Hu Huan , Bai Xinyi , Qian Yihui , Guo Daixin , Ai Kun , Zhu Yuchen , Huang Long 
Published: October 2024

AbstractIntroductionAn increasing body of evidence suggests a close association between COVID‐19 infection and the safety of PD‐1/PD‐L1 inhibitor therapy in cancer patients. However, the available data concerning these impacts remain limited and occasionally contradictory.Material and MethodsWe conducted a retrospective analysis of cancer patients who received PD‐1/PD‐L1 inhibitor therapy at the same institution from November 2022 to May 2023. After excluding patients with missing information, a total of 224 cases were included. In our study, immune‐related adverse events (irAEs) that occurred during the hospitalization of patients were included in the analysis. Further analysis of inter‐subgroup differences was conducted following a 1:2 propensity score matching. Statistical analyses were performed using the Fisher's exact, chi‐squared, and Mann–Whitney U‐tests.ResultThe results showed that no statistically significant differences between the two subgroups in the incidence of irAEs, changes in immune function before and after using PD‐1/PD‐L1 inhibitors, and alterations in hepatic and renal function (p > 0.05).ConclusionOur findings suggest that infection with COVID‐19 does not significantly impact the safety of PD‐1/PD‐L1 inhibitors in cancer patients. Most cancer patients used PD‐1/PD‐L1 inhibitors during COVID‐19 infection (asymptomatic or mild infection) did not experience exacerbation of their underlying condition, nor did they exhibit a substantial increase in toxic side effects.
EphA‐Mediated Regulation of Stomatin Expression in Prostate Cancer Cells
Authors: Nishida Masanari , Sato Akira , Shimizu Akio , Rahman Nor Idayu A. , Wada Akinori , Kageyama Susumu , Ogita Hisakazu 
Published: October 2024

ABSTRACTBackground and AimsTumor growth and progression are affected by interactions between tumor cells and stromal cells within the tumor microenvironment. We previously showed that the expression of an integral membrane protein, called stomatin, was increased in cancer cells following their association with stromal cells. Additionally, stomatin impaired the Akt signaling pathway to suppress tumor growth. However, it remains unclear how stomatin expression is regulated. To explore this, we examined the cell surface molecules that can transduce the intercellular communication signals between cancer cells and stromal cells.ResultsAmong these molecules, EphA3 and EphA7 receptors and their ligand ephrin‐A5 were found to be expressed in prostate cancer cells, but not in prostate stromal cells. Cell‐to‐cell contact of prostate cancer cells through the EphA–ephrin‐A interaction suppressed stomatin expression, while knockdown of EphA3/7 or ephrin‐A5 increased stomatin expression. This increase contributed to an inhibition of prostate cancer cell proliferation. Intracellularly, the binding of ephrin‐A to EphA attenuated extracellular signaling‐regulated kinase (ERK) activation that promoted stomatin expression. Furthermore, ELK1 and ELK4, which are Ets family transcription factors phosphorylated by ERK, were involved in the induction of stomatin expression. We also found that higher Gleason score prostate cancer tissue samples had increased activation of EphA, while the stomatin expression and activated ERK and ELK levels were all low. In the mouse xenograft tumor samples generated by implantation of prostate cancer cells, EphA3 phosphorylation was attenuated and the ERK–ELK signaling and stomatin expression were enhanced in the area where stromal cells infiltrated the tumor.ConclusionThe EphA‐mediated signaling suppresses the ERK–ELK pathway, leading to the reduction of stomatin expression that affects prostate cancer malignancy.
The Performance of Ethylene Partial Oxidation on Group IB Metal Stepped Surfaces
Authors: Huang Hong , Guo Zhongyuan , Wei Li , Xiong Wei , Li Hao 
Published: October 2024

Group IB metal catalysts, particularly Ag, Au, and Cu, exhibit particular selectivity for ethylene oxide (EO) formation, while Ag demonstrating the highest performance so far. Previous studies have explored the EO formation mechanism on (100) and (111) surfaces of group IB metals, but the reaction mechanism on the (211) facet (analogous to the edge sites of a catalyst particle) remains poorly understood. Herein, we fill in the knowledge gap by analyzing ethylene partial oxidation to EO on the (211) surfaces of Ag, Au, and Cu through density functional theory (DFT) calculations, scaling relationship analysis, and microkinetic modeling. Our study demonstrates that the (211) surface decreases the energy barrier for the dissociation of oxygen molecules into oxygen atoms, while unfavorable for the production of EO. Therefore, we should preserve an appropriate concentration of (211) surface on the nanoparticles when designing catalysts for the ethylene epoxidation reaction.
Investigating the Effects of Induction Heating on a Submerged Hollow Cylindrical Element
Authors: Shami Umar Tabrez , Shami Tabrez Aslam 
Published: October 2024

ABSTRACTThis article proposes an induction heating element that addresses heat transfer and thermal homogenization while being fully submerged in a liquid, specifically focusing on heating of water as a case study. The design calculations, fabrication, and realization of a resonant induction heating system that heats the proposed heating element are presented. The geometric shape of proposed heating element is a hollow cylinder that maintains structural strength while delivering required thermal energy because of an external time‐varying magnetic field. Detailed mathematical modeling of the proposed heating element's equivalent electric circuit has been presented while considering physical parameters including diameter, thickness, height, material properties, magnetic field frequency, and skin effect. A laboratory scale prototype of the induction heating system including the proposed heating element has been built, and experiments have been demonstrated. The experimental results of the working induction heating resonant inverter and RLC resonant circuit inductance and capacitance with induction load are presented. Additionally, the results of thermographic images and temperature–time profile of the water sample, which was heated using the proposed heating element, are provided to demonstrate the heating element's reliability and practicality. This research contributes to the field of induction heating technology by investigating a heating element that is submerged in a liquid medium, resulting in a uniform temperature distribution throughout the liquid. The conventional method of heating water in a stainless steel cup‐shaped container is an inefficient heat transfer process. In stainless steel cup‐shaped containers, a portion of the energy input used to boil the water is lost to the environment through the surface area of the container that is not in direct contact with the water. This heat loss occurs due to the container's design, which exposes a large surface area to the surrounding environment, allowing thermal energy to dissipate through conduction, convection, and radiation.
Relationship Between Evolutionary Diversity and Aboveground Biomass During 150 Years of Natural Vegetation Regeneration in Temperate China
Authors: Tian Qilong , Zhang Xiaoping , Wang Miaoqian , He Jie , Xu Xiaoming , He Liang , Yi Haijie , Wang Haojia 
Published: October 2024

ABSTRACTWhile the link between plant species diversity and biomass has been well‐studied, the impact of evolutionary diversity on community biomass across long timescales or ongoing change remains a subject of debate. We elucidated the association between evolutionary diversity and community aboveground biomass (AGB) using an ideal experimental system with over 150‐year history of natural vegetation regeneration. Higher phylogenetic diversity facilitated the sampling effect under the influence of environmental filtering, and caused an increase in AGB. Phylogenetic structure varied from aggregation to dispersion during the later period of vegetation recovery (70–150 years), which was correlated with increases in niche complementarity and increasing AGB. Woody plant evolutionary diversity was used as a key to predict the relationship between vegetation recovery and AGB, with a total explanatory power of ~84.7%. Mixed forests composed of evergreen conifers and deciduous broadleaf forests had higher carbon sequestration potential than that of pure forests, which is advantageous for increasing top‐stage AGB. This research expands our knowledge of the causes and effects of biodiversity and ecosystem function dynamics over time and space, which is important for accurately predicting future climate change effects.
An Invasion Risk Assessment of Alien Woody Species in Potential National Park Sites in Xinjiang, China, Under Climate Change
Authors: Zhang Fei‐Xue , Li Hong‐Li , Wan Ji‐Zhong 
Published: October 2024

ABSTRACTThe invasion of alien woody species may have broad ecological, economic, and health impacts on ecosystems and biodiversity under climate change. Previous studies showed that disrupting the biodiversity conservation mechanisms in protected areas can seriously threaten natural ecosystems and the protection of rare and endangered species in such protected areas. However, there is currently no standard for evaluating the invasion risk of woody plants under climate change when establishing national parks in China. Therefore, we used a species distribution model to evaluate the invasion risk of 250 invasive alien woody species in potential national park sites in Xinjiang under climate change. The results indicated that the probability of forest invasion in the potential Altai Kanas National Park was determined to be significantly higher than that of the average level in Xinjiang nature reserves, both under current and future climate conditions. At the same time, the probability of invasive woody species invading coniferous forests, broad‐leaved forests, and grassland ecosystems is higher in the Altai Kanas and Tianshan potential national parks. We found that Acer negundo, Robinia pseudoacacia, and Amorpha fruticose in potential parks in Xinjiang have higher invasion potential and thus require heightened vigilance to stop their spread. This study contributes to the monitoring and management of national parks and provides an actionable foundation for protecting ecosystem functions and minimizing the potential risk of invasive alien species under climate change.
From Pb‐based MAPbI3−xClx to Pb‐free FASnI3−xClx and CsSbCl4 derivatives fabrication in atmospheric conditions for optoelectronic and solar cell applications
Authors: Kamruzzaman M. , Hossain Md. Faruk , Zapien J. Antonio , Karim A. M. M. Tanveer , Das H. N. , Helal M. A. 
Published: October 2024

AbstractMAPbI3 is the most attractive perovskite, but toxicity and instability issues hinder its commercial applications. Stability can be improved by halide mixing; however, Pb‐free perovskites are designed to alleviate the toxicity and to enable green photovoltaics (PVs). To this end, MAPbI3‐xClx, FASnI3‐xClx and CsSbCl4 films are deposited by spay pyrolysis technique in atmospheric conditions. SEM images demonstrated that through this process, high quality film fabrication is possible. Color of the precursor solutions changes with stirring time. High crystallinity and existence of mixed‐phases are confirmed by XRD analysis. Compositions greatly impact the morphology and optical properties. Value of α is larger than 105 cm−1 for all films. Band gaps of FASnI3‐xClx and CsSbCl4 are 1.46 eV and 1.52 eV, which are more suitable for PVs, optoelectronic applications than MAPbI3‐xClx (Eg = 1.59 eV). The efficiency was obtained as 16.34%, 9.90%, and 13.08% for deposited MAPbI3‐xClx, FASnI3‐xClx, and CsSbCl4 films. The lower efficiency can further be enhanced by optimizing parameters, and in this study it was found as 20.78%, 11.93%, and 18.02%. Theoretical calculations show the films can easily produce O2 by a strong oxidation process. Thus, the favorable characteristics of FASnI3‐xClx and CsSbCl4 make alternative Pb‐free perovskites for PV, electronic, and optoelectronic applications.image
A distributed load balancing architecture based on in‐band network telemetry
Authors: Li Mingfa , Shi Huiling , Tan Lizhuang , Zhang Wei 
Published: October 2024

AbstractA data center (DC) is supposed to efficiently distribute the bandwidth of the network to provide high‐quality traffic transmission. However, the load imbalance issue can easily occur due to the complex topology and traffic features. Equal‐Cost Multi‐Path(ECMP) distributes traffic on different paths but doesn't consider network congestion. Although HULA solved some of ECMP's problems, it can easily congest the best path. RPS randomly distributes packets across multiple paths, potentially causing packet reordering in certain scenarios. This paper presents DHLB, a distributed hop‐by‐hop load balancing architecture based on in‐band network telemetry. With active In‐band network telemetry, DHLB gathers essential load information and systematically records it in a load information table. DHLB distributes traffic proportionally on different paths based on their load degree. We build a fat tree topology on mininet to verify the performance of our design. Experimental results indicate that DHLB outperforms other schemes regarding average Flow Completion Time (FCT). It also performs better on additional overhead than another probe‐based scheme.
Incorporating multiracial and multiethnic experiences into genetic counseling practice and research: A necessary opportunity
Authors: Lowe Chenery , Gomez‐Stafford Justin , Martschenko Daphne O. 
Published: October 2024

AbstractThe conflation of race and genetic ancestry can have harmful consequences. Biological conceptualizations of race have long been used to justify inequities and distract from social structures that afford opportunities to some that are unjustly denied to others. Despite recent efforts within the scientific community to distinguish between the sociopolitical constructs of race and ethnicity and the biological constructs of genetic ancestry and genetic similarity, their conflation continues to influence genomic research and its translation into clinical care. One overlooked aspect of this problematic conflation is the extent to which discrete monoracial and monoethnic categorization systems persist and perpetuate unequal benefit‐sharing in the clinical translation of genomic technologies. In genetic service delivery, reliance on discrete racial and ethnic categories undermines the clinical translation of genomic technologies for large segments of the global population. For multiracial and multiethnic individuals, who have complex identities that defy discrete categorization systems, the potential benefits of genomic discoveries are especially elusive. Scholars have recently begun to call for the inclusion of multiracial, multiethnic, and admixed individuals in race, ethnicity, and ancestry frameworks in genetics and genomics. However, little work has been done to explore and address the unique challenges and opportunities posed by multiracial/multiethnic individuals in genetic counseling specifically. We discuss how conceptualizing diversity along discrete racial and ethnic lines perpetuates inequitable patient care and limits efforts to increase inclusion and belonging within genetic counseling. Moreover, we argue that ongoing efforts to mitigate racial inequity must actively challenge the paradigm of monoracial and monoethnic categories to accomplish their goal.
Emergence of IGH::CCND1 rearrangement and mutations in TP53, BTK, and BCL2 associated with therapy resistance in chronic lymphocytic leukemia
Authors: Wei Qing , Fang Hong , Jing James M. , Segura‐Rivera Roman , Medeiros L. Jeffrey , Wang Wei 
Published: October 2024

AbstractChronic lymphocytic leukemia (CLL) is an indolent low‐grade B‐cell neoplasm that generally responds well to treatment. Rarely, CLL cases exhibit an IGH::CCND1 rearrangement, presenting a diagnostic challenge in distinguishing between clonal evolution within CLL and an independent mantle cell lymphoma. We report a case of CLL with the emergence of an IGH::CCND1 rearrangement and mutations associated with treatment resistance, including TP53, BTK, and BCL2, during disease progression. Immunophenotypic, cytogenetic, and molecular analyses support that these alterations are secondary events within the CLL clone. This case demonstrates dynamic clonal selection and expansion in response to treatments, which, in turn, contributes to treatment resistance.
In this lifetime: A narrative inquiry examining older, Black, same‐gender‐loving male couples’ relationship resiliency and longevity
Authors: Ferguson Alfonso L. , Johnson Marlon , Rose Breon , Landrum DaeQuawn 
Published: October 2024

AbstractThis narrative inquiry examines the humanistic experiences of three Black, same‐gender‐loving (SGL) male couples to understand what contributes to their resiliency and longevity. Through quare theory as an analytical frame for thematic analysis, findings highlighted storytellers’ eras of assimilation, respect, and wisdom as tools for fostering relationship resiliency and longevity. Counseling practitioners, educators, and researchers are encouraged to broach and avoid reductionist viewpoints when cultivating belongingness and improving and maintaining connections with this population.
MRI at low field: A review of software solutions for improving SNR
Authors: Ayde Reina , Vornehm Marc , Zhao Yujiao , Knoll Florian , Wu Ed X. , Sarracanie Mathieu 
Published: October 2024

AbstractLow magnetic field magnetic resonance imaging (MRI) ( < 1 T) is regaining interest in the magnetic resonance (MR) community as a complementary, more flexible, and cost‐effective approach to MRI diagnosis. Yet, the impaired signal‐to‐noise ratio (SNR) per square root of time, or SNR efficiency, leading in turn to prolonged acquisition times, still challenges its relevance at the clinical level. To address this, researchers investigate various hardware and software solutions to improve SNR efficiency at low field, including the leveraging of latest advances in computing hardware. However, there may not be a single recipe for improving SNR at low field, and it is key to embrace the challenges and limitations of each proposed solution. In other words, suitable solutions depend on the final objective or application envisioned for a low‐field scanner and, more importantly, on the characteristics of a specific low field. In this review, we aim to provide an overview on software solutions to improve SNR efficiency at low field. First, we cover techniques for efficient k‐space sampling and reconstruction. Then, we present post‐acquisition techniques that enhance MR images such as denoising and super‐resolution. In addition, we summarize recently introduced electromagnetic interference cancellation approaches showing great promises when operating in shielding‐free environments. Finally, we discuss the advantages and limitations of these approaches that could provide directions for future applications.
Energy optimal path planning for wheeled mobile robots with circular obstacle
Authors: Kim Youngjin , Singh Tarunraj 
Published: October 2024

AbstractThe energy optimal motion planning algorithm for a differential drive robot with a circular obstacle in the maneuver space is introduced in this article. Rather than the traditional unicycle model, a non‐canonical state space model of the kinematics of a wheeled mobile robot is used to formulate the optimal control problem. The necessary conditions for optimality are formally derived using calculus of variations, resulting in constraints for the costates when the inequality constraint become active, revealing that the controls are required to be continuous. The optimality conditions permit decomposing the motion planning problem in two independent segments: prior to and after activation of the inequality constraints. Analytical expressions for the evolving states and control are found to be a function of Jacobi elliptic functions, permitting reducing the optimal control problem to a root‐finding problem. A comprehensive parametric study is included to demonstrate the impact on the optimal trajectories by varying the radius of the obstacle. The study shows that there are three distinct maneuver strategies with respect to the size of the obstacle. Furthermore, by including entering and exit time as optimization variables, a methodology for generalizing the development to any given motion scenario is developed and numerically illustrated.