bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simulated microgravity‐induced dysregulation of cerebrospinal fluid immune homeostasis by disrupting the blood–cerebrospinal fluid barrier
Authors: Yang Jing , Cui Yaoyuan , Zhao Juan , Tang Shiyi , Wang Anqing , Wang Junxiao , Chen Yu , Luo Jilong , Wang Guan , Yan Junhao , Du Jichen , Wang Jiawei 
Published: September 2024

AbstractBackgroundThe blood–cerebrospinal fluid barrier (BCSFB) comprises the choroid plexus epithelia. It is important for brain development, maintenance, function, and especially for maintaining immune homeostasis in the cerebrospinal fluid (CSF). Although previous studies have shown that the peripheral immune function of the body is impaired upon exposure to microgravity, no studies have reported changes in immune cells and cytokines in the CSF that reflect neuroimmune status. The purpose of this study is to investigate the alterations in cerebrospinal fluid (CSF) immune homeostasis induced by microgravity and its mechanisms. This research is expected to provide basic data for brain protection of astronauts during spaceflight.MethodsThe proportions of immune cells in the CSF and peripheral blood (PB) of SMG rats were analyzed using flow cytometry. Immune function was evaluated by measuring cytokine concentrations using the Luminex method. The histomorphology and ultrastructure of the choroid plexus epithelia were determined. The concentrations of intercellular junction proteins in choroid plexus epithelial cells, including vascular endothelial‐cadherin (VE‐cadherin), zonula occludens 1 (ZO‐1), Claudin‐1 and occludin, were detected using western blotting and immunofluorescence staining to characterize BCSFB injury.ResultsWe found that SMG caused significant changes in the proportion of CD4 and CD8 T cells in the CSF and a significant increase in the levels of cytokines (GRO/KC, IL‐18, MCP‐1, and RANTES). In the PB, there was a significant decrease in the proportion of T cells and NKT cells and a significant increase in cytokine levels (GRO/KC, IL‐18, MCP‐1, and TNF‐α). Additionally, we observed that the trends in immune markers in the PB and CSF were synchronized within specific SMG durations, suggesting that longer SMG periods (≥21 days) have a more pronounced impact on immune markers. Furthermore, 21d‐SMG resulted in ultrastructural disruption and downregulated expression of intercellular junction proteins in rat choroid plexus epithelial cells.ConclusionsWe found that SMG disrupts the BCSFB and affects the CSF immune homeostasis. This study provides new insights into the health protection of astronauts during spaceflight.
Exploring the impact of acetylsalicylic acid and conditioned medium obtained from mesenchymal cells, individually and in combination, on cognitive function, histological changes, and oxidant–antioxidant balance in male rats with hippocampal injury
Authors: Zangiabadi Iman , Ilaghi Mehran , Shamsara Ali , Eftekhar‐Vaghefi Seyed Hassan , Saheli Mona , Shabani Mohammad 
Published: September 2024

AbstractBackgroundThe hippocampus is susceptible to damage, leading to negative impacts on cognition. Conditioned medium (CM) obtained from adipose tissue–derived mesenchymal stem cells (MSCs) and acetylsalicylic acid (ASA) have shown neuroprotective effects independently. This study explored the synergistic potential of ASA and CM from adipose‐derived MSCs against hippocampal injury.MethodsAdult male Wistar rats received bilateral hippocampal ethidium bromide (EB) injections to induce hippocampal damage. Rats were treated with ASA and/or CM derived from adipose tissue MSCs every 48 h for 16 days. Behavioral tests (open field test, Morris water maze, novel object recognition, and passive avoidance), oxidative stress, Western blot analysis of brain‐derived neurotrophic factor (BDNF) and cerebral dopamine neurotrophic factor (CDNF) expression, and hippocampal histological investigation were conducted.ResultsAdministration of EB caused impairments in spatial, recognition, and passive avoidance memory, as well as heightened oxidative stress, reduced BDNF/CDNF expression, and pyramidal cell loss in the hippocampal CA1 region. Administration of ASA, CM, or a combination of both mitigated these hippocampal damages and cognitive deficits, elevated BDNF and CDNF levels, and alleviated the CA1 necrosis caused by EB. Moreover, co‐administering ASA and CM resulted in greater improvements in spatial memory compared to administering ASA alone, suggesting possible synergistic interactions.ConclusionsThe ability of ASA, CM obtained from adipose tissue–derived MSCs, and their combination therapy to alleviate hippocampal injuries highlights their promising therapeutic potential as a neuroprotection strategy against brain damage. Our findings provide preliminary evidence of the potential synergistic effects of ASA and CM, which warrants further investigations.
Senior management's sustainability commitment and environmental performance: Revealing the role of green human resource management practices
Authors: Qalati Sikandar Ali , Siddiqui Faiza , Magni Domitilla 
Published: September 2024

AbstractThe significance of firm environmental performance (FEP) has been recognized by academic experts. Nevertheless, a comprehensive exploration of the driving factors behind it remains lacking. In order to bridge this gap, this study employs the perspective of the Triple Bottom Line theory and explores the influence of senior management sustainability commitment (SMSC) and green human resource management practices (GHRMP) on FEP. Furthermore, the study explores the direct and mediating role of GHRMP on the SMSC–FEP relationship. The moderation role of environmental knowledge and green organizational culture was also explored. A questionnaire with closed‐ended questions was sent online to 321 manufacturing companies, followed by analysis using SmartPLS 4.0. The results of this study indicate that SMSC has a significant influence on both GHRMP and FEP. Elucidation is provided in the discourse relating to the theoretical and practical contribution. Additionally, the limitations and potential for further inquiry are specified.
Carbon‐coated current collectors in lithium‐ion batteries and supercapacitors: Materials, manufacture and applications
Authors: Hao Hongqing , Tan Rui , Ye Chunchun , Low Chee Tong John 
Published: September 2024

AbstractThe current collector is a crucial component in lithium‐ion batteries and supercapacitor setups, responsible for gathering electrons from electrode materials and directing them into the external circuit. However, as battery systems evolve and the demand for higher energy density increases, the limitations of traditional current collectors, such as high contact resistance and low corrosion resistance, have become increasingly evident. This review investigates the functions and challenges associated with current collectors in modern battery and supercapacitor systems, with a particular focus on using carbon coating methods to enhance their performance. Surface coating, known for its simplicity and wide applicability, emerges as a promising solution to address these challenges. The review provides a comprehensive overview of carbon‐coated current collectors across various types of metal and nonmetal substrates in lithium‐ion batteries and supercapacitors, including a comparative analysis of coating materials and techniques. It also discusses methods for manufacturing carbon‐coated current collectors and their practical implications for the industry. Furthermore, the review explores prospects and opportunities, highlighting the development of next‐generation high‐performance coatings and emphasizing the importance of advanced current collectors in optimizing energy device performance.
Two‐dimensional carbonitride MXenes: From synthesis to properties and applications
Authors: Zhang Weiwei , Li Shibo , Fan Xiachen , Zhang Xuejin , Fan Shukai , Bei Guoping 
Published: September 2024

AbstractCarbonitride MXenes, such as Ti3CNTx, Ti2C0.5N0.5Tx, and Ti4(C0.2N0.8)3Tx, have attracted much interest in the large family of two‐dimensional (2D) nanomaterials. Like their carbide MXene counterparts, the nanolayered structure and functional groups endow carbonitride MXenes with an attractive combination of physical and chemical properties. More interestingly, the replacement of C by N changes the lattice parameters and electron distribution of carbonitride MXenes due to the greater electronegativity of N as compared to C, thus resulting in significantly enhanced functional properties. This paper reviews the development of carbonitride MXenes, the preparation of 2D carbonitride MXenes, and the current understanding of the microstructure, electronic structure, and functional properties of carbonitride MXenes. In addition, applications, especially in energy storage, sensors, catalysts, electromagnetic wave shielding and absorption, fillers, and environmental and biomedical fields, are summarized. Finally, their current limitations and future opportunities are presented.
Lactonization of Diols Over Highly Efficient Metal‐Based Catalysts
Authors: Tan Xiaomeng , Min Rui , Wang Shiyu , Ning Hui , Mu Baoquan , Cao Ning , Yan Wenjuan , Jin Xin , Yang Chaohe 
Published: September 2024

AbstractLactones has gained increasing attention in recent years due to wide application in polymer and pharmaceutical industries. Traditional synthetic methods of lactones often involve harsh operating temperature, use of strong alkalis and toxic oxidants. Therefore, lactonization of diols under milder conditions have been viewed as the most promising route for future commercialization. A variety of metal catalysts (Ru, Pt, Ir, Au, Fe, Cu, Co, and Zn) have been developed for highly efficient oxidant‐, acceptor‐, base‐ and additive‐free lactonization processes. However, only a few initial attempts have been reported with no further details on catalytic mechanism being disclosed in literature. There demands a systematic study of the mechanistic details and the structure‐function relationship to guide the catalyst design. In this work, we critically reviewed and discussed the structure‐function relationship, the catalytic reaction mechanism, the catalyst stability, as well as the effect of oxidant and solvent for lactonization of diols. This work may provide additional insights for the development of other oxygen‐containing functional molecules for material science and technologies.
Ventenata dubia projected to expand in the western United States despite future novel conditions
Authors: Nietupski Ty C. , Kim John B. , Tortorelli Claire M. , Lemons Rebecca , Kerns Becky K. 
Published: September 2024

AbstractDistributions of both native and invasive species are expected to shift under future climate. Species distribution models (SDMs) are often used to explore future habitats, but sources of uncertainty including novel climate conditions may reduce the reliability of future projections. We explore the potential spread of the invasive annual grass ventenata (Ventenata dubia) in the western United States under both current and future climate scenarios using boosted regression tree models and 30 global climate models (GCMs). We quantify novel climate conditions, prediction variability arising from both the SDMs and GCMs, and the agreement among GCMs. Results demonstrate that currently suitable habitat is concentrated inside the invaded range of the northwest, but substantial habitat exists outside the invaded range in the Southern Rockies and southwestern US mountains. Future suitability projections vary greatly among GCMs, but GCMs commonly projected decreased suitability in the invaded range and increased suitability along higher elevations of interior mountainous areas. Climate novelty did not appear to undermine the prediction reliability in many cases where the climate–species relationship was fully represented by the occurrence data. GCM‐derived variability resulting from variation in future cool season precipitation and temperature seasonality was greatest in the Rocky Mountains. SDM‐derived variability was higher in currently suitable habitat, and few GCMs projections agreed that these areas would contain future suitable habitat. However, while prediction variability was high, many GCM projections agreed that parts of the Rocky, Wasatch, and Uinta Mountains would contain highly suitable habitat in the future. As disturbances in the interior mountains occur in coming decades, reducing some natural barriers to invasion, land managers, and conservationists will need to monitor for ventenata in post‐disturbance environments. Changes to invasion potential may not play out for several decades, but results related to current potential may have applications for early detection and rapid response planning.
High frequency of silent mutations in gyrA gene of Mycobacterium tuberculosis in Indian isolates
Authors: Gupta Anamika , Pal Sudhir K. , Nema Vijay 
Published: September 2024

AbstractReporting any uncommon or untapped changes in bacterial genetics or physiology would be of great importance to support the drug development process. We studied 120 Mycobacterium tuberculosis clinical isolates with different geographical origin within India and their resistance profile and found a significant number of isolates (109) harboring the polymorphism at nucleotide positions 61 and 284 of the gyrA gene. Bioinformatics analysis of these changes for drug binding suggested no significant change in the binding of the drug but have lower binding energies as compared with the wild‐type proteins. Although functionally silent for the gyrA gene, these changes are indicating a silent geographical and evolutionary change that needs to be further studied for drug discovery and bacterial fitness.
Investigation of society's sensitivity to environmental pollution and electronic waste in Turkey
Authors: Yalçın Ahmet Burak , Güneş‐Durak Sevgi 
Published: September 2024

AbstractA questionnaire survey was conducted to identify the factors that are effective in assessing people's attitudes toward e‐waste pollution prevention. Reliability analysis, normality distribution analysis, correlation and regression analysis, independent sample t‐test, and one‐way analysis of variance (ANOVA) were performed on the data obtained through IBM SPSS Statistics 25. In this way, it was determined to what extent the level of public awareness of e‐waste, environmental concerns, empathy, and moral norms toward the environment are affected by socio‐demographic factors. According to the study results, a significant relationship was found between environmental concerns, environmental pollution awareness, environmental responsibility, personal moral norms and educational status, and empathy and moral norms. In addition, limited growth, anthropocentrism, fragility of the balance of nature, educational status, and having children were also found to have a significant relationship with environmental concerns. However, a significant relationship was found between marital status and environmental concerns, empathy and moral norms. A significant relationship was also found between age group and empathy and moral norms.
The dawn of a sexual assault relief center: A 12‐year fact‐finding survey of victims of sexual assault conducted since 2010 by SACHICO, Japan's first rape crisis center
Authors: Kusumoto Yuki , Kobayashi Eiji , Yagi Asami , Ishida Emi , Miyazawa Aya , Kikuchi Kaori , Kudara Kana , Shimada Katsuko , Yamamasu Seiichi , Ueda Yutaka , Kimura Tadashi , Kato Haruko 
Published: September 2024

AbstractObjectiveIn Japan, amidst insufficient legal provisions and governmental support, in 2010, the first rape crisis center, the Sexual Assault Crisis Healing Intervention Center Osaka (SACHICO) was established. We compared SACHICO visitor data from 2010 to 2021 with National Police Agency statistics to clarify the current situation of sexual assault victims in Japan and considered future issues for Japan to address.MethodsThis study was a cross‐sectional study that analyzed the data described below. All visitations to SACHICO between April 2010 and December 2021 were considered targets for data totaling. Data on crime statistics were gathered from the official governmental statistics portal site.ResultsA total of 12 036 visitations occurred, of which 3189 were first‐time consultations; 3100 initial medical examinations were conducted, and no medical examination was conducted in the remaining 89 cases (2.7%). The number of initial medical examinations increased 3.7 times from 2010 to 2021. Victims under the age of 19 comprised 60% of the total number of initial medical examinations (1863/3100). The reporting rate for all 3100 initial medical examinations was only 31.3% (969/3100) of the cases. The proportion of forcible sexual intercourse versus forcible indecency were the converse of those observed among acknowledged cases nationwide and in Osaka Prefecture. For several years, the number of initial medical consultations at SACHICO has exceeded that of acknowledged cases in Osaka Prefecture.ConclusionSupport for victims of sexual assault in Japan is still insufficient. It is necessary to strengthen the system of rape crisis centers system to realize an unbroken chain of support for victims.
Efficacy of non‐lead ammunition distribution programs to offset fatalities of golden eagles in southeast Wyoming
Authors: Slabe Vincent A. , Crandall Ross H. , Katzner Todd , Duerr Adam E. , Miller Tricia A. 
Published: September 2024

AbstractGolden eagles (Aquila chrysaetos) face many anthropogenic risks including illegal shooting, electrocution, collision with wind turbines and vehicles, and lead poisoning. Minimizing or offsetting eagle deaths resulting from human‐caused sources is often viewed as an important management objective. Despite understanding the leading anthropogenic sources of eagle fatalities, existing scientific research supports few practical solutions to mitigate these causes of death. We implemented a non‐lead ammunition distribution program in southeast Wyoming, USA, and evaluated its effectiveness as a compensatory mitigation action to offset incidental take (i.e., fatalities) of golden eagles at wind energy facilities. In 2020 and 2022, we distributed non‐lead ammunition to 699 hunters with big‐game tags specific to our >400,000‐ha study area. These hunters harvested 296 pronghorn (Antilocapra americana), 14 deer (Odocoileus spp.), and 33 elk (Cervus canadensis) in the study area, which accounted for 6.9% and 6.5% of the harvest in these hunt units in 2020 and 2022, respectively. We used road surveys in 2020 to estimate a density of 0.036 (95% CI = 0.018–0.058) golden eagles/km2 during the big game hunting season in our study area. Model output suggests that our non‐lead ammunition distribution program offset the fatality of 3.84 (95% CI = 1.06–23.72) eagles over the course of these 2 hunting seasons. Our work illustrates the potential usefulness of non‐lead ammunition distribution programs as an action to mitigate eagle fatalities caused by wind facilities or other anthropogenic causes of death.
The early peak knee abduction moment waveform is a novel risk factor predicting anterior cruciate ligament injury in young athletes: A prospective study
Authors: Sigurðsson Haraldur Björn , Fl Pétursdóttir Melkorka Katrín , Briem Kristín 
Published: September 2024

AbstractPurposeIn this study, prospective data were used to evaluate whether the early peak knee abduction moment waveform is associated with the risk of anterior cruciate ligament (ACL) injury.MethodsBiomechanical data from 84 athletes who participated in the study as adolescents were analysed after cross‐referencing national health registry data to confirm ACL reconstruction in the subsequent years. The knee abduction moment waveform shape was obtained with cluster analysis for the first 100 ms of a cutting manoeuvre (1776 trials in total) and classified as either containing an early peak knee abduction moment or not, and the odds ratio for later ACL injury was then calculated. Additionally, discrete kinematic and kinetic variables were extracted, and tested against the risk of ACL injury using mixed model logistic regression.ResultsOf 84 athletes, 8 (all female) sustained a total of 13 ACL injuries in the years after motion analysis data collection. Six clusters of knee abduction moment waveform shapes were identified. Two clusters containing 446 trials were classified as an early peak knee abduction waveform. This waveform was associated with a 7.2‐fold increase in the risk of ACL injury (95% confidence interval: 2.4–24.6; p < 0.001). Of the kinematic and kinetic variables tested, only the knee abduction angle at initial contact was associated with an increased risk of ACL injury (p < 0.001).ConclusionThis is the first study to confirm the association between the early peak knee abduction moment waveform and the risk of ACL injury. Using waveforms, instead of discrete peak values of the knee abduction moment, may better represent risky movement patterns. Replicating these findings in a larger cohort will support the use of this method to screen athletes for risk and guide targeted preventive interventions and their efficacy.Level of EvidenceLevel II.
Research on Pulse Current Cathodic Protection Technology for Long‐Distance Pipeline: A Review
Authors: Zhao Qiudie , Li Hongfu , Luo Xiaowu , Shi Yanjie , Li Jian , Wang Chen , Liu Yanming , Lv Xianghong 
Published: September 2024

ABSTRACTAs an important infrastructure for oil and gas transportation, the safe and stable operation of long‐distance pipelines is significant for guaranteeing national energy security and economic development. However, pipelines are susceptible to corrosion due to various factors. Therefore, it is crucial to take effective corrosion protection measures. Pulse current cathodic protection technology, as an advanced pipeline corrosion protection technology, is superior to traditional cathodic protection technology. This paper mainly summarizes the research progress of pulse current cathodic protection technology for long‐distance pipelines in recent years. It briefly discusses the protection mechanism, characteristic parameters, challenges, and development trends of pulse current cathodic protection technology, which provides a useful reference for the further promotion and application of pulse current cathodic protection technology for long‐distance transport pipelines.
On the Impact of Cathodic Polarization on the Chloride Threshold of Carbon Steel in Alkaline Solutions
Authors: Fache Konstantin , Keßler Sylvia , Harnisch Jörg 
Published: September 2024

ABSTRACTThis study investigates the influence of cathodic polarization on the chloride threshold (CT) for carbon steel in alkaline solutions, analogous to reinforcing steel embedded in concrete, with a focus on the electrochemical steel potential as a critical factor for corrosion initiation. The research, incorporating a literature review and potentiostatic tests, reveals that CT shows potential independence at potentials more anodic than −200 mVSCE and increases for potentials more cathodic than −200 mVSCE. The observed increase in CT under cathodic polarization is attributed to alterations in the passive layer composition, supporting the existence of distinct potential regions that govern the onset of corrosion.