bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Metalgel with Liquid Metal Continuum Immobilized in Polymer Network
Authors: Wang Jiacheng , Ye Tingting , Jiao Yiding , Ren Weitong , Li Yiran , Li Xusong , Li Yiran , Li Dan , Li Fangyan , Wang Yuanzhen , Song Jie , Zou Kuangyi , Mao Wei , Wu Ming , Tan Ruiyang , Lu Jiang , He Er , Wang Lie , Chen Hao , Li Luhe , Li Qianming , Bai Chenyu , Gao Rui , Ren Junye , Li Wenfei , Cao Yi , Zhang Ye 
Published: October 2024

AbstractGels are formed by fluids that expand throughout the whole volume of 3D polymer networks. To unlock unprecedented properties, exploring new fluids immobilized in polymer networks is crucial. Here, a new liquid metal‐polymer gel material termed “metalgel” is introduced via fluid replacement strategy, featuring 92.40% vol liquid metal fluid as a continuum immobilized by interconnected nanoscale polymer network. The unique structure endows metalgel with high electrical conductivity (up to 3.18 × 106 S·m‒1), tissue‐like softness (Young's modulus as low as 70 kPa), and low gas permeability (4.50 × 10‒22 m2·s‒1·Pa‒1). Besides, metalgel demonstrates electrical stability under extreme deformations, such as being run over by a 4.5‐metric‐tonne truck, and maintains its integrity in various environments for up to 180 days. The immobilization of high‐volume‐fraction liquid metal fluid is realized by electrostatic interactions is further revealed. Potential applications for metalgel are diverse and include soft electromagnetic shielding, hermetic sealing, and stimulating/sensing electrodes in implantable bioelectronics, underscoring its broad applicability.
Lead‐Free Perovskite Light‐Emitting Diodes
Authors: Tang Weidong , Liu Shengnan , Zhang Gan , Ren Zhixiang , Liu Zhe , Zhang Meng , Zhang Shi‐Yuan , Zou Chen , Zhao Baodan , Di Dawei 
Published: October 2024

AbstractMetal halide perovskites have been identified as a promising class of materials for light‐emitting applications. The development of lead‐based perovskite light‐emitting diodes (PeLEDs) has led to substantial improvements, with external quantum efficiencies (EQEs) now surpassing 30% and operational lifetimes comparable to those of organic LEDs (OLEDs). However, the concern over the potential toxicity of lead has motivated a search for alternative materials that are both eco‐friendly and possess excellent optoelectronic properties, with lead‐free perovskites emerging as a strong contender. In this review, the properties of various lead‐free perovskite emitters are analyzed, with a particular emphasis on the more well‐reported tin‐based variants. Recent progress in enhancing device efficiencies through refined crystallization processes and the optimization of device configurations is also discussed. Additionally, the remaining challenges are examined, and propose strategies that may lead to stable device operation. Looking forward, the potential future developments for lead‐free PeLEDs are considered, including the extension of spectral range, the adoption of more eco‐friendly deposition techniques, and the exploration of alternative materials.
Dynamic Lock‐And‐Release Mechanism Enables Reduced ΔG at Low Temperatures for High‐Performance Polyanionic Cathode in Sodium‐Ion Batteries
Authors: Li Shuqiang , Lu Xueying , Li Yu , Wang Huaizhi , Sun Yufeng , Zhou Qiannan , Yue Jiasheng , Guo Ruiqi , Wu Feng , Wu Chuan , Bai Ying 
Published: October 2024

AbstractLow‐temperature synthesis of polyanionic cathodes for sodium‐ion batteries is highly desirable but often plagued by prolonged reaction times and suboptimal crystallinity. To address these challenges, a novel self‐adaptive coordination field regulation (SACFR) strategy based on a dynamic lock‐and‐release (DLR) mechanism is introduced. Specifically, urea is used as a DLR carrier during synthesis, which dynamically “locks” and “releases” vanadium ions for controlled release, simultaneously “locking” H+ ions to enhance phosphate group release, thereby creating a self‐adaptive coordination field that can intelligently respond to real‐time demands of the reaction system. This dynamic coordination behavior contributes to both an improvement in reaction kinetics and a significant reduction in Gibbs free energy change (ΔG). As a result, the kinetic efficiency and thermodynamic spontaneity of the reaction are greatly enhanced, enabling the efficient synthesis of high‐crystalline Na3V2O2(PO4)2F (NVOPF) at 90 °C within just 3 hours. The as‐prepared NVOPF cathode exhibits exceptional rate performance and ultra‐stable cycling stability across a broad temperature range. Furthermore, the successful kilogram‐scale synthesis underscores the practical potential of the innovative strategy. This work pioneers the regulation of coordination field chemistry for polyanionic cathode synthesis, providing transformative insights into material design.
Nanoplastics: Immune Impact, Detection, and Internalization after Human Blood Exposure by Single‐Cell Mass Cytometry
Authors: Fusco Laura , Gazzi Arianna , Giro Linda , Schefer Roman B. , D'Almeida Sènan Mickael , Cagliani Roberta , Zoccheddu Martina , Uyar Recep , Besbinar Ömur , Çelik Doğantan , Yilmazer Acelya , Mitrano Denise M. , Orecchioni Marco , Delogu Lucia Gemma 
Published: October 2024

AbstractThe increasing exposure to nanoplastics (NPs) raises significant concerns for human health, primarily due to their potential bioaccumulative properties. While NPs have recently been detected in human blood, their interactions with specific immune cell subtypes and their impact on immune regulation remain unclear. In this proof‐of‐concept study, model palladium‐doped polystyrene NPs (PS‐Pd NPs) are utilized to enable single‐cell mass cytometry (CyTOF) detection. The size‐dependent impact of carboxylate polystyrene NPs (50–200 nm) is investigated across 15 primary immune cell subpopulations using CyTOF. By taking advantage of Pd‐doping for detecting PS‐Pd NPs, this work evaluates their impact on human immune‐cells at the single‐cell level following blood exposure. This work traces PS‐Pd NPs in 37 primary immune‐cell subpopulations from human blood, quantifying the palladium atom count per cell by CyTOF while simultaneously assessing the impact of PS‐Pd NPs on cell viability, functionality, and uptake. These results demonstrate that NPs can interact with, interfere with, and translocate into several immune cell subpopulations after exposure. In vivo distribution experiments in mice further confirmed their accumulation in immune cells within the liver, blood, and spleen, particularly in monocytes, macrophages, and dendritic cells. These findings provide valuable insights into the impact of NPs on human health.
Bio‐Inspired Wettability Integrated System for Environmentally Adaptable Fog Harvesting
Authors: Guo Jie , Guo Zhiguang , Liu Weimin 
Published: October 2024

AbstractFog represents an underestimated water resource, particularly in arid coastal areas where the abundance of fog makes fog harvesting a highly viable and operational option. In response to the limitations of traditional fog harvesting techniques, biomimetic fog harvesting materials with special wettable surfaces have emerged as a promising solution, offering a notable enhancement in water collection efficiency (WCE). This work presents a bio‐inspired multi‐strategy fog harvesting material integrated with a wettability contrast pattern and asymmetric wettability. The implementation of multiple strategies at each stage of fog harvesting synergistically improves the WCE of aluminum plates by up to 53%. A solar‐powered active fog‐collecting system is devised based on this material to cope with changing environments, which demonstrates a significant improvement in WCE compared to a conventional fog net, reaching up to 736.67% under a static fog environment. This work provides a viable design of bio‐inspired fog harvesting materials and offers a promising approach for their large‐scale implementation.
Thermally Activated Delayed Fluorescence Sensitizer with Through‐Space Charge Transfer Manipulated by Atom Distribution for Solution‐Processed Deep‐Blue Multi‐Resonance OLEDs
Authors: Shi Song , Wang Xingdong , Zhao Lei , Lv Jianhong , Shao Shiyang , Wang Lixiang 
Published: October 2024

AbstractOrganic light‐emitting diodes (OLEDs) employing multi‐resonance (MR) emitters have attracted much attention due to their high luminescent efficiency and color purity, however, the development of deep‐blue multi‐resonance OLEDs is hindered by the lack of suitable sensitizers. Here a novel design strategy is reported for thermally activated delayed fluorescence sensitizer with high reverse intersystem crossing (kRISC) and radiative transition (kR) rate by regulating atom distribution of a spatially‐aligned carbazole donor/diphenylpyrimidine acceptor structure to manipulate through‐space charge transfer (CT) process. It is found that diphenylpyrimidine acceptor with 1,3‐position nitrogen atoms is un‐conjugated to bridging phenyl moiety by the conjugation node of pyrimidine, while the acceptor with 1,5‐position nitrogen atoms is conjugated to bridging phenyl through conjugation site, opening through‐bond CT pathway via bridging phenyl besides through‐space CT from spatial donor‐acceptor interactions. As a result, the sensitizer with 1,5‐position nitrogen atoms exhibits enhanced oscillator strength by 3.5 folds and accelerated kR of 3.57 × 107 s−1, while keeping high kRISC of 4.03 × 106 s−1 and high singlet (S1) state (2.88 eV). Solution‐processed OLEDs using the sensitizer and deep‐blue multi‐resonance emitter exhibit efficient narrowband electroluminescence with CIE coordinates of (0.14, 0.13) and EQEmax of 15.6%, representing the state‐of‐the‐art device performance for deep‐blue multi‐resonance OLEDs by solution process.
Characterization of modified low‐density polyethylene by cold atmospheric pressure plasma jet treatment in the melt state
Authors: Bertin Maicon , Fiedler Holger , Leitao Erin M. , Bickerton Simon , Verbeek Casparus Johannes Reinhard 
Published: October 2024

AbstractCold plasma treatment in the melt state is a novel area of research focused on producing modified polymers, hence more research on the underlying plasma‐polymer interactions in this context is needed. In this study, low‐density polyethylene (LDPE) was treated with a cold atmospheric pressure plasma jet (CAPPJ) during melt processing in a polymer batch mixer. Electron spin resonance (ESR) results proved that plasma treatment effectively generates free radicals in the material, increasing the room temperature spin concentration by an order of magnitude to 2 × 1015 spins g−1. The generated radicals react mainly by cross‐linking, forming a gel phase of up to 31%, and consequently increasing the polymer's melt viscosity. Furthermore, oxidation was established as solely a thermal effect limited by radical availability at the interface exposed to the atmosphere, whereas plasma exposure did not lead to further oxidation. Interestingly, plasma appears to interact with the thermally created ketone groups, possibly forming unsaturated carbonyl compounds.
A promising pullulan/PLA composite: Influence of pullulan in the scaffolds morphology constructed by 3D printing
Authors: Silva Neto Thalita , Maia Lana S. , Zanata Leonardo , Conceição Monique O. T. , Medeiros Simone F. , Faria Maria Ismênia S. D. , Rosa Derval S. , Mulinari Daniella R. 
Published: October 2024

AbstractManufacturing three‐dimensional scaffolds with significant rough and porous structures is advantageous in tissue regeneration approaches influencing cell growth. Thus, this work aims to study the effect of using different Pullulan contents (PULL) in the poly(lactic) acid (PLA) matrix for 3D printing scaffolds. PLA composites filler with PULL (5 and 10% wt.) were prepared in a thermokinetic mixer, extruded in a machine, and then used to print samples using a fused deposition modeling (FDM) 3D printer. The prepared filaments and scaffolds were characterized using Field emission scanning electron microscopy (FESEM), Fourier‐transform infrared spectroscopy (FTIR), thermogravimetry analyses (TGA), water contact angle (WCA), differential scanning calorimetry (DSC), and hardness techniques. The insertion of PULL into the PLA matrix influenced the increase in diameter and roughness, and density reduction of the composite filaments compared to pristine PLA. Furthermore, the filler promoted an increase in thermal stability, shore hardness, and the development of promising morphological characteristics for cell growth because the walls of the scaffolds are more robust and have more regular‐sized holes. The scaffold fabrication reinforced with 10% PULL presented high surface roughness (up to 1022% if compared with pristine PLA), and open pores can be confirmed successfully compared to pristine PLA. Thus, the use of PULL as a filler in a PLA matrix guarantees the development of composite scaffolds with improved morphological and hardness properties, which could allow the possibility of future research into the application of the proposed material (10% wt. PULL) as an ecologically correct and biocompatible alternative for application in tissue engineering.
Sputtered Zero‐Excess Electrodes with Metallic Seed Layers for Solid‐State Sodium Batteries
Authors: Lowack Ansgar , Grun Paula , Anton Rafael , Auer Henry , Nikolowski Kristian , Partsch Mareike , Kusnezoff Mihails , Michaelis Alexander 
Published: October 2024

AbstractZero‐excess sodium metal solid‐state batteries offer improved safety, lower cost, higher energy density, and reduced resource dependency compared to today's lithium‐ion technology. This study demonstrates the fabrication of zero‐excess electrodes with unprecedented stability during plating/stripping cycles. The fabrication process involves the sputter deposition of 20 nm metallic seed layers – zinc, silver, indium, or tin – onto NASICON (Na3.4Zr2Si2.4P0.6O12) ceramic separators, followed by the sputter deposition of a 30 μm copper current collector. The favorable influence of these seed layers on the in‐situ formation of the sodium|NASICON interface is examined through nucleation and cycling experiments, with a sodium metal reservoir serving as the non‐limiting counter electrode. Due to alloy formation the seed layers – particularly tin – stabilize sodium nucleation and cycling substantially and reduce dendrite formation compared to reference cells with bare copper current collectors. Sodium loss during cycling is primarily attributed to local cracking of the current collector and its partial delamination from the NASICON. Compared to polished NASICON, a roughened surface reduces the resistance e. g. of the counter electrode 200‐fold to approx. 1 Ωcm2 at 3 MPa and suppresses delamination further.
Beyond clinical trials: CDK4/6 inhibitor efficacy predictors and nomogram model from real‐world evidence in metastatic breast cancer
Authors: Liu Binliang , Hu Zhe‐Yu , Xie Ning , Liu Liping , Li Jing , Yang Xiaohong , Xiao Huawu , Zhao Xuran , Tian Can , Wu Hui , Lu Jun , Gao Jianxiang , Hu Xuming , Cao Min , Shui Zhengrong , Tang Yu , Ouyang Quchang 
Published: October 2024

AbstractBackgroundCDK4/6 inhibitors (CDK4/6i) have shown promising results in the treatment of hormone receptor‐positive (HR+) metastatic breast cancer (MBC) when combined with endocrine therapy (ET). It is crucial to evaluate the actual effectiveness and safety of CDK4/6i in clinical practice, as well as to analyze the factors that can predict their outcomes.MethodsPatients with HR+ MBC who received CDK4/6i‐based therapy between May 2016 and May 2023 at Hunan Cancer Hospital were evaluated for progression‐free survival (PFS). Adverse reactions were assessed based on the National Cancer Institute Common Toxicity Criteria (version 5.0).ResultsThis study included 344 patients, with a median PFS (mPFS) of 12.8 months (range: 10.4–15.2 months). After adjustment, Cox multivariate regression analysis revealed that visceral metastasis (specifically liver and brain metastases), Eastern Cooperative Oncology Group Performance Status (ECOG PS) ≥ 1, estrogen receptor ≤ 80%, progesterone receptor ≤ 10%, Ki‐67 > 30%, and treatment in later stages were significant factors associated with reduced PFS. Based on this, we created a prognostic nomogram and validated its performance, obtaining a C‐index of 0.714 (95% confidence interval: 0.640–0.787) as well as reliable calibration and clinical impact. The mPFS of CDK4/6i rechallenge was 7.7 months; for patients who initially discontinued CDK4/6i for reasons other than disease progression, CDK4/6i rechallenge still provided a mPFS of 11.4 months. The tolerability and safety of combining CDK4/6is with ET were manageable. Adverse events led to treatment discontinuation in 3.8% of patients. Neutropenia (29.1%), leukopenia (13.7%), and anemia (4.1%) were the primary grade 3/4 adverse reactions.ConclusionsThis real‐world study highlights the ample efficacy and reasonable safety of combined CDK4/6i and ET in patients with HR+ MBC. Individualized treatment decisions and ongoing safety monitoring are important to optimize the therapeutic benefit of CDK4/6i treatment.
Ethnic and racialized disparities in the use of screening services for pap smears and mammograms in Canada
Authors: Salami Bukola O. , Kalenga Cindy Z. , Olukotun Mary , Renzaho Andre M. N. , Maduforo Aloysius Nwabugo , Serrano‐Lomelin Jesus A. , Tunde‐Byass Modupe , King Regine U. , Richter Solina , Ladha Tehseen , Senthilselvan Ambikaipakan , Bailey Paul , Ospina Maria B. 
Published: October 2024

AbstractBackgroundBreast and cervical cancers pose significant health challenges for women globally, emphasizing the critical importance of effective screening programs for early detection. In Canada, despite the implementation of accessible healthcare systems, ethnic and racialized disparities in cancer screening persist. This study aims to assess ethnic and racialized disparities in breast and cervical cancer screening in Canada.MethodsUsing 2015–2019 data from the Canadian Community Health Survey, we analyzed women aged 18–70 in distinct ethnic and racial groups. The primary outcome was mammography or Papanicolaou test (pap smear). The secondary outcome was time since the last screening. We used weighted multivariable logistic regression to estimate the odds of having a pap smear or mammography across the ethnic and racialized groups, adjusted for relevant covariates. Results were reported as odds ratios (ORs) with 95% confidence intervals (CIs).ResultsWe included 14,628,067 women of which 72.5% were White, 8.4% Southeast Asian, 4.7% South Asian, 3.4% Indigenous, 2.7% Black, 2.0% West Asian, and 1.6% Latin American. In comparison with the White reference group, a higher odds ratio of not having a pap smear was estimated for the West Asian (5.63; CI 3.85, 8.23), South Asian (5.19; CI 3.79, 7.12), Southeast Asian (4.35; CI 3.46, 5.46), and Black groups (2.62; CI 1.82, 3.78). Disparities in mammography screening were found only for the Southeast Asian group with higher odds of not having screening (1.85; CI 1.15, 2.98) compared to the White reference group.ConclusionThis study reveals significant disparities in pap smear and mammography screenings affecting various ethnic groups, particularly in West Asia, South Asian, and Black communities. These findings underscore the urgent need for targeted interventions, policies, and healthcare strategies to address these gaps and ensure equitable access to essential breast and cervical cancer prevention across all ethnicity.
Simultaneous diagnosis of adult‐onset Still's disease and lymphoma: A case report and systematic review of the literature
Authors: Bayala Yannick Laurent Tchenadoyo , Ouedraogo Issa , Mourfou Hervé Eric , Son Bakoubassé Aïssata , Yameogo Wendyam Nadège , Tinni Ismael Ayouba , Zabsonré Tiendrébéogo Wendlassida Joëlle Stéphanie , Ouedraogo Dieu‐Donné 
Published: October 2024

Key Clinical MessageDifferentiating Adult‐Onset Still's Disease (AOSD) from lymphoma is challenging. A 23‐year‐old female presented with polyarthralgia, fever, rash, lymphadenopathy, and abnormal labs. She met AOSD criteria and was diagnosed with non‐Hodgkin lymphoma. Treatment led to improvement.AbstractThe differentiation between Adult‐onset Still's Disease (AOSD) and lymphoma remains challenging in our context. The Faustrel score facilitates the simultaneous diagnosis of these conditions. A 23‐year‐old woman presented with chronic polyarthralgia in a febrile context. A physical examination revealed peripheral joint syndrome, a maculopapular rash on the trunk, and peripheral lymphadenopathy. Laboratory tests showed neutrophils leukocytosis, hyperferritinemia, and a glycosylated ferritin fraction of 12%. A lymph node biopsy revealed a malignant non‐Hodgkin lymphoma, and the patient met the diagnostic criteria for AOSD according to Faustrel. She received corticosteroid therapy and four courses of Rituximab. After 6 months, clinical and biological improvements were noted. It is essential to consider the possibility of an association between atypical clinical presentations of lymphoma and AOSD.
A rare case of lumbar facet fracture‐dislocation and review of the literature
Authors: Wang Chien Chieh , Wu Tsung‐Mu , Chien Chi‐Sheng , Huang Chi‐Ming , Wong Kin Weng 
Published: October 2024

Key Clinical MessageLumbar facet fracture‐dislocation is rare, often due to hyperflexion with rotational force. Abnormal scoliosis on radiography is a key sign, prompting further imaging. Facetectomy and laminectomy ensure safe reduction, while instrumented fusion is an effective surgical treatment.AbstractTraumatic lumbar facet dislocation is an uncommon condition, particularly when unilateral lumbar facet dislocation is accompanied by a contralateral facet fracture. The patient had a locked facet joint at the left L4–L5, a fracture of the right superior articular process of L5 and a comminuted fracture at the peritrochanteric region of the right femur following a fall. Emergent operation was conducted, starting with open reduction and fixation for the right proximal femur, followed by posterior open reduction and posterolateral fusion with instrumentation, without interbody fusion, for the lumbar spine injury. The patient exhibited positive outcomes throughout the follow‐up. This article highlights the trauma mechanism of lumbar facet dislocation, emphasizing hyperflexion with rotational force. Abnormal local scoliosis is a distinctive imaging sign of facet joint dislocation. Facetectomy and laminectomy are recommended for safe reduction and instrumented fusion is considered a safe and effective surgical treatment for facet joint dislocation injuries.