bluuebunny/crossref_metadata_2025_split huggingface dataset:
High-quality genome sequence of the radioresistant bacterium Deinococcus ficus KS 0460
Authors: Matrosova Vera Y. , Gaidamakova Elena K. , Makarova Kira S. , Grichenko Olga , Klimenkova Polina , Volpe Robert P. , Tkavc Rok , Ertem Gözen , Conze Isabel H. , Brambilla Evelyne , Huntemann Marcel , Clum Alicia , Pillay Manoj , Palaniappan Krishnaveni , Varghese Neha , Mikhailova Natalia , Stamatis Dimitrios , Reddy TBK , Daum Chris , Shapiro Nicole , Ivanova Natalia , Kyrpides Nikos , Woyke Tanja , Daligault Hajnalka , Davenport Karen , Erkkila Tracy , Goodwin Lynne A. , Gu Wei , Munk Christine , Teshima Hazuki , Xu Yan , Chain Patrick , Woolbert Michael , Gunde-Cimerman Nina , Wolf Yuri I. , Grebenc Tine , Gostinčar Cene , Daly Michael J. 
Published: July 2017

AbstractThe genetic platforms of Deinococcus species remain the only systems in which massive ionizing radiation (IR)-induced genome damage can be investigated in vivo at exposures commensurate with cellular survival. We report the whole genome sequence of the extremely IR-resistant rod-shaped bacterium Deinococcus ficus KS 0460 and its phenotypic characterization. Deinococcus ficus KS 0460 has been studied since 1987, first under the name Deinobacter grandis, then Deinococcus grandis. The D. ficus KS 0460 genome consists of a 4.019 Mbp sequence (69.7% GC content and 3894 predicted genes) divided into six genome partitions, five of which are confirmed to be circular. Circularity was determined manually by mate pair linkage. Approximately 76% of the predicted proteins contained identifiable Pfam domains and 72% were assigned to COGs. Of all D. ficus KS 0460 proteins, 79% and 70% had homologues in Deinococcus radiodurans ATCC BAA-816 and Deinococcus geothermalis DSM 11300, respectively. The most striking differences between D. ficus KS 0460 and D. radiodurans BAA-816 identified by the comparison of the KEGG pathways were as follows: (i) D. ficus lacks nine enzymes of purine degradation present in D. radiodurans, and (ii) D. ficus contains eight enzymes involved in nitrogen metabolism, including nitrate and nitrite reductases, that D. radiodurans lacks. Moreover, genes previously considered to be important to IR resistance are missing in D. ficus KS 0460, namely, for the Mn-transporter nramp, and proteins DdrF, DdrJ and DdrK, all of which are also missing in Deinococcus deserti. Otherwise, D. ficus KS 0460 exemplifies the Deinococcus lineage.
The WFSA Global Anesthesia Workforce Survey
Authors: Kempthorne Peter , Morriss Wayne W. , Mellin-Olsen Jannicke , Gore-Booth Julian 
Published: July 2017

BACKGROUND:
Safe anesthesia and surgical care are not available when needed for 5 billion of the world’s 7 billion people. There are major deficiencies in the specialist surgical workforce in many parts of the world, and specific data on the anesthesia workforce are lacking.

METHODS:
The World Federation of Societies of Anaesthesiologists conducted a workforce survey during 2015 and 2016. The aim of the survey was to collect detailed information on physician anesthesia provider (PAP) and non-physician anesthesia provider (NPAP) numbers, distribution, and training. Data were categorized according to World Health Organization regional groups and World Bank income groups.

RESULTS:
We obtained information for 153 of 197 countries, representing 97.5% of the world’s population. There were marked differences in the density of PAPs between World Health Organization regions and between World Bank income groups, ranging from 0 to over 20 PAP per 100,000 population. Seventy-seven countries reported a PAP density of <5, with particularly low densities in the African and South-East Asia regions. NPAPs make up a large part of the global anesthesia workforce, especially in countries with limited resources. Even when NPAPs are included, 70 countries had a total anesthesia provider density of <5 per 100,000. Using current population data, over 136,000 additional PAPs would be needed immediately to achieve a minimum density of 5 per 100,000 population in all countries.

CONCLUSIONS:
The World Federation of Societies of Anaesthesiologists Global Anesthesia Workforce Survey is the most comprehensive study of the global anesthesia workforce to date. It is the first step in a process of ongoing data collection and longitudinal follow-up. The authors recommend an interim goal of at least 5 specialist physician anesthesia providers (anesthesiologists) per 100,000 population. A marked increase in training of PAPs and NPAPs will need to occur if we are to have any hope of achieving safe anesthesia for all by 2030.
The initiator caspase Dronc plays a non-apoptotic role in promoting DNA damage signalling in D. melanogaster
Authors: Khan Chaitali , Muliyil Sonia , Ayyub Champakali , Rao Basuthkar J. 
Published: July 2017

ABSTRACT
The phosphorylation of the variant histone H2Ax (denoted γH2Ax; γH2Av in flies) constitutes an important signalling event in DNA damage sensing, ensuring effective repair by recruiting DNA repair machinery. In contrast, the γH2Av response has also been reported in dying cells, where it requires activation of caspase-activated DNases (CADs). Moreover, caspases are known to be required downstream of DNA damage for cell death execution. We show here, for the first time, that the Drosophila initiator caspase Dronc acts as an upstream regulator of the DNA damage response (DDR) independently of executioner caspases by facilitating γH2Av signalling, possibly through a function that is not related to apoptosis. Such a γH2Av response is mediated by ATM rather than ATR, suggesting that Dronc function is required upstream of ATM. In contrast, the role of γH2Av in cell death requires effector caspases and is associated with fragmented nuclei. Our study uncovers a novel function of Dronc in response to DNA damage aimed at promoting DDR via γH2Av signalling in intact nuclei. We propose that Dronc plays a dual role that can either initiate DDR or apoptosis depending upon its level and the required threshold of its activation in damaged cells.
This article has an associated First Person interview with the first author of the paper.
Community engagement for the rapid elimination of malaria: The case of Kayin State, Myanmar
Authors: Kajeechiwa Ladda , Thwin May Myo , Nosten Suphak , Tun Saw Win , Parker Daniel , von Seidlein Lorenz , Tangseefa Decha , Nosten François , Cheah Phaik Yeong 
Published: July 2017

Background: Currently, malaria elimination efforts are ongoing in several locations across Southeast Asia, including in Kayin State (also known as Karen State), Myanmar. This paper describes the community engagement efforts for a pilot malaria elimination project, the challenges encountered and lessons learnt. Methods: Between May 2013 and June 2015, a study on targeted malaria elimination (TME) that included mass drug administration was conducted in four villages (TPN, TOT, KNH, and HKT) of Kayin State. Community engagement efforts included workshops, meetings and house-to-house visits with community members. Exhibitions related to malaria and fun activities were organized for children. In addition, we provided primary care, small individual incentives and village-level incentives. This paper is based on our analysis of data extracted from meeting minutes, field notes, feedback sessions among staff and with community members as well as our own reflections. Results: Average participation across three rounds of MDA were 84.4%, 57.4%, 88.6% and 59.3% for TPN, TOT, KNH and HKT, respectively. Community engagement was fraught with practical challenges such as seasonal tasks of the villagers. There were challenges in explaining difficult concepts like drug resistance and submicroscopic infection. Another was understanding and navigating the politics of these villages, which are located in politically contested areas. Managing expectations of villagers was difficult as they assumed that the community team must know everything related to health. Conclusions: In the TME project, many different community engagement strategies were employed. We encountered many challenges which included logistical, scientific and political difficulties. An approach that is tailored to the local population is key.
Are All Spillovers Created Equal? A Network Perspective on Information Technology Labor Movements
Authors: Wu Lynn , Jin Fujie , Hitt Lorin M. 
Published: July 2017

This study examines how characteristics of an interfirm labor-flow network affect firm productivity. Using employee job histories to trace labor movement between organizations, we construct labor-flow networks for both information technology (IT) and non-IT labor and analyze how a firm’s network structure for the two types of labor affects its performance. We find that hiring IT workers from a structurally diverse network of firms can substantially improve firm productivity, but that the same is not true for non-IT labor, where we find little benefit of network diversity. We hypothesize that these results reflect differences in the types of knowledge diffusion facilitated by different types of labor flows, with IT labor enabling the transfer of new and innovative firm practices, which benefits from diversity, while non-IT labor flows are more closely associated with implementation of complementary organizational practices, which may benefit from a critical mass of workers with a common knowledge base. Together, these results demonstrate the importance of incorporating a network perspective in understanding the full impact of spillover effects from organizational hiring activities. This paper was accepted by Chris Forman, information systems.
Dynamic Quality Ladder Model Predictions in Nonrandom Holdout Samples
Authors: Xu Linli , Silva-Risso Jorge M. , Wilbur Kenneth C. 
Published: July 2017

In light of recent calls for further validation of structural models, this paper evaluates the popular dynamic quality ladder (DQL) model using a nonrandom holdout approach. The model is used to predict data following a regime shift—that is, a change in the environment that produced the estimation data. The prediction performance is evaluated relative to a benchmark vector autoregression (VAR) model across three automotive categories and multiple prediction horizons. Whereas the VAR model performs better in all scenarios in the compact car category, the DQL model tends to perform better on multiple-year horizons in both the midsize car and full-size pickup categories. A supplementary data analysis suggests that DQL model performance in the nonrandom holdout prediction task is better in categories that are more affected by the regime shift, helping to validate the usefulness of the dynamic structural model for making predictions after policy changes. This paper was accepted by Matthew Shum, marketing.
Understanding Team Knowledge Production: The Interrelated Roles of Technology and Expertise
Authors: Teodoridis Florenta 
Published: July 2017

Teamwork is an increasingly important aspect of knowledge production. In particular, factors influencing team formation relative to the composition of expertise are crucial for both organizational performance and for informing policy. In this paper, I draw attention to technology access as a highly influential factor impacting expertise in team formation. I examine the hack of Microsoft Kinect as an exogenous event that suddenly reduced motion-sensing technology costs. I show that great reductions in technology costs substitute for ex ante optimal involvement of area specialists and facilitate involvement of outside-area specialists through collaboration with researchers with broader knowledge—generalists. In other words, technology costs influence the composition of expertise in teamwork, with sufficiently large reductions leading to knowledge creation that combines more broadly across knowledge areas. These findings have important implications for organizations and policy makers in crafting incentives for more diverse knowledge creation through strategic investments that lower technology costs and influence team formation. Data are available at https://doi.org/10.1287/mnsc.2017.2789 . This paper was accepted by Lee Fleming, entrepreneurship and innovation.
Tendon injuries
Authors: Wu Fan , Nerlich Michael , Docheva Denitsa 
Published: July 2017

Tendons connect muscles to bones, ensuring joint movement. With advanced age, tendons become more prone to degeneration followed by injuries. Tendon repair often requires lengthy periods of rehabilitation, especially in elderly patients. Existing medical and surgical treatments often fail to regain full tendon function. The development of novel treatment methods has been hampered due to limited understanding of basic tendon biology. Recently, it was discovered that tendons, similar to other mesenchymal tissues, contain tendon stem/progenitor cells (TSPCs) which possess the common stem cell properties. The current strategies for enhancing tendon repair consist mainly of applying stem cells, growth factors, natural and artificial biomaterials alone or in combination. In this review, we summarise the basic biology of tendon tissues and provide an update on the latest repair proposals for tendon tears. Cite this article: EFORT Open Rev 2017;2:332-342. DOI: 10.1302/2058-5241.2.160075
Book Reviews
Authors: Kenyon Andrew , Cuelenaere Eduard , Damme Kristin Van 
Published: July 2017

Abstract
Media Pluralism and Diversity: Concepts, Risks and Global Trends, Peggy Valcke, Miklós Sükösd and Robert Picard (eds) (2016) London: Palgrave Macmillan, 362 pp., ISBN: 9781137304292, h/bk, $109
New Patterns in Global Television Formats, Karina Aveyard, Albert Moran and Pia Majbritt Jensen (eds) (2016) Bristol: Intellect, 345 pp., ISBN: 9781783207121, p/bk, £35
News for a Mobile-First Consumer, P. M. Pointdexter (2016) New York: Peter Lang, 272 pp., ISBN: 9781433128400, p/bk, Є44
Teaching the ‘people’s music’ at the ‘people’s college’: Popular music education in the junior college curriculum in Los Angeles, 1924–55
Authors: Krikun Andrew 
Published: July 2017

Abstract
The historical foundations of formal popular music education in post-secondary institutions in the United States has rarely been explored. This article provides an overview of the seminal popular music courses and degree programmes at three post-secondary public institutions, from their establishment in the 1920s until the 1950s. Several important music educators responsible for these innovative programmes are profiled, including band director Audre Stong at Pasadena City College, department chair Leslie Clausen at Los Angeles City College and band director Dwight Defty, who introduced the first popular music degree programme, Modern Music, in 1936 at Long Beach City College. Factors that led to the introduction of popular music in the curriculum included the expansion of vocational education in California public schools, softening the boundary between highbrow and lowbrow musical traditions in the Los Angeles music scene, strong local public school music education and the democratic movement towards student- and community-centred education.
Higher order intrinsic weak differentiability and Sobolev spaces between manifolds
Authors: Convent Alexandra , Van Schaftingen Jean 
Published: July 2017

Abstract
We define the notion of higher-order colocally weakly differentiable maps from a manifold M to a manifold N.
When M and N are endowed with Riemannian metrics,

p
≥
1

{p\geq 1}

and

k
≥
2

{k\geq 2}

, this allows us to define the intrinsic higher-order homogeneous Sobolev space

W
˙

k
,
p

⁢

(
M
,
N
)

{\dot{W}^{k,p}(M,N)}

.
We show that this new intrinsic definition is not equivalent in general with the definition by an isometric embedding of N in a Euclidean space; if the manifolds M and N are compact, the intrinsic space is a larger space than the one obtained by embedding. We show that a necessary condition for the density of smooth maps in the intrinsic space

W
˙

k
,
p

⁢

(
M
,
N
)

{\dot{W}^{k,p}(M,N)}

is that

π

⌊

k
⁢
p

⌋

⁢

(
N
)

≃

{
0
}

{\pi_{\lfloor kp\rfloor}(N)\simeq\{0\}}

.
We investigate the chain rule for higher-order differentiability in this setting.
New solutions for critical Neumann problems in ℝ2
Authors: Deng Shengbing , Musso Monica 
Published: July 2017

Abstract
We consider the elliptic equation

{-\Delta u+u=0}

in a bounded, smooth domain Ω in

{\mathbb{R}^{2}}

subject to the nonlinear Neumann boundary condition

{\frac{\partial u}{\partial\nu}=\lambda ue^{u^{2}}}

, where ν denotes the outer normal vector of

{\partial\Omega}

. Here

{\lambda>0}

is a small parameter. For any λ small we construct positive solutions concentrating, as

{\lambda\to 0}

, around points of the boundary of Ω.
Bürgerengagement in Zeiten des demographischen Wandels: Die Rolle von Büchereien und anderen sozialen Infrastruktureinrichtungen im Dorf
Authors: Franzen Nathalie 
Published: July 2017

Zusammenfassung
Durch den wirtschaftlichen und demographischen Strukturwandel in den Dörfern veränderte sich auch das Zusammenleben der ländlichen Gesellschaft: die Infrastruktureinrichtungen wie auch die Arbeitsplätze sind meist in den Ballungsräumen. Dies fordert aber auch das bürgerschaftliche Engagement, das mit neuen Wegen und Angeboten das soziale und kulturelle Leben im Dorf wieder bereichern kann. Gute Beispiele hauptsächlich aus Rheinland-Pfalz werden zeigen, dass so das Miteinander aller Generationen gefördert werden kann.
Optimism, Pessimism, Audit Uncertainty, and Tax Compliance
Authors: Lee Kangoh 
Published: July 2017

AbstractAs the tax authority releases or withholds relevant information, it decrease or increases the extent of uncertainty about the audit probability taxpayers perceive, affecting their reporting behavior and expected tax revenues. The effects of an increase in enforcement uncertainty on the expected tax revenues depend on taxpayer pessimism or optimism and on additional information about the audit probability taxpayers receive. The expected tax revenues tend to increase in response to an increase in audit uncertainty, and the tax authority would have little incentive to release more information to the extent that it cares about tax revenues.
Ultimate Longitudinal Strength of Composite Ship Hulls
Authors: Zhang Xiangming , Huang Lingkai , Zhu Libao , Tang Yuhang , Wang Anwen 
Published: July 2017

AbstractA simple analytical model to estimate the longitudinal strength of ship hulls in composite materials under buckling, material failure and ultimate collapse is presented in this paper. Ship hulls are regarded as assemblies of stiffened panels which idealized as group of plate-stiffener combinations. Ultimate strain of the plate-stiffener combination is predicted under buckling or material failure with composite beam-column theory. The effects of initial imperfection of ship hull and eccentricity of load are included. Corresponding longitudinal strengths of ship hull are derived in a straightforward method. A longitudinally framed ship hull made of symmetrically stacked unidirectional plies under sagging is analyzed. The results indicate that present analytical results have a good agreement with FEM method. The initial deflection of ship hull and eccentricity of load can dramatically reduce the bending capacity of ship hull. The proposed formulations provide a simple but useful tool for the longitudinal strength estimation in practical design.
Modified Minimal Error Method for Nonlinear Ill-Posed Problems
Authors: Sabari M. , George Santhosh 
Published: July 2017

Abstract
An error estimate for the minimal error method for nonlinear ill-posed problems under general a Hölder-type source condition is not known. We consider a modified minimal error method for nonlinear ill-posed problems. Using a Hölder-type source condition, we obtain an optimal order error estimate. We also consider the modified minimal error method with noisy data and provide an error estimate.
Optimisation of Design and Operation Parameters for Multicomponent Separation via Improved Lewis-Matheson Method
Authors: Ching Tiong Ching , Nandong Jobrun 
Published: July 2017

Abstract
Distillation is the most commonly used separation and purification technique in the chemical and allied industries despite that it has been known as the most energy-consuming unit in process industry. The need to reduce this energy consumption has become one of the important focuses in the efficient design and optimization of distillation processes. In the present work, we propose an improved Lewis-Matheson stage-by-stage procedure by incorporating the Fenske equation to enhance the estimation of the non-key component distributions, and thus avoiding infeasible solutions to the stage-by-stage system of equations of mass and energy balances. A modified theta method is also included in the design procedure to satisfy the feed stage matching criteria which help reduces the computational time while increasing the accuracy of feed composition matching. By using the proposed modified Lewis-Matheson method, an optimization is conducted in Matlab environment where the problem formulation takes into account both sets of design and operating parameters with specified product purity as the constraint. The objective function of the optimization is to minimize the Total Annualized Cost (TAC), which includes both capital and operating costs. The effectiveness of the proposed design procedure is demonstrated using an industrial-scale natural gas liquids (NGLs) depropanizer fractionation unit.
Autorität heute – mit Arendt über sie hinaus
Authors: Miller Simone Rosa 
Published: July 2017

AbstractIn her essay “What is authority” Hannah Arendt wonders whether “What was authority?” would have been the more appropriate title. This paper aims to show that authority is indeed a contemporary phenomenon and one that is taking on ever greater significance. Arendt’s work on authority is used to support conclusions that she herself did not draw. These can be useful for the understanding of authority within today’s political and civil realms. With respect to the political system of representative democracies, the paper challenges Arendt’s claim that authority has vanished from contemporary societies and points to two new figures of authority, namely the expert and the populist. It diagnoses the comeback of the old antagonism between a metaphysical and a democratic justification of authority.
Brief aus Norwegen
Authors: Erbacher Christian 
Published: July 2017

Abstract
Building on my experiences as a student, PhD candidate and researcher, this “letter from Norway” presents some characteristics of philosophy at the University of Bergen. First, I describe a basic philosophy course that is obligatory for each student at the university. As this “examen philosophicum” provides a common ground for graduates from all subjects, philosophy is still present in Norwegian public discourse. Second, I follow one specific thread in the history of Bergen’s philosophy department, focusing on the philosophy of language and Wittgenstein studies that began with the first professor and is still practiced, for example with recent digital editing. In this context I also sketch the working conditions for PhD-students and researchers today. Finally, a brief exposition of the original praxeology of Jakob Meløe allows me to formulate what I found so characteristic of philosophy in Bergen: the recognition and appreciation of specific and individual experiences in doing philosophy.
Continuous Addition Polymerization
Authors: Beginn Uwe 
Published: July 2017

AbstractFree- and controlled radical polymerizations have become standard reactions in the research laboratory to prepare a large variety of homo- and copolymers. Hence, the synthetic polymer chemist is frequently asked to supply a colleague or a project partner with 10 - 20 g of some (co)polymer. The usual mode of action is the "batch polymerization": Solvent, initiator and monomers are mixed and heat under an inert atmosphere until (almost) full conversion of the monomer has been achieved. Sometimes the researcher is not aware the fact, that this simple procedure is ineffective when used to prepared larger quantities of homopolymers and it will produce a messy product in many copolymerization reactions.