bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harnessing Machine Learning for QSPR Modeling of Corrosion Inhibitors in HCl for Mild Steel Protection
Authors: Bouziani Idrissi Mohammed , Moumen Idriss , Taghzouti Sara , Sayin Koray , Chakir El Mahjoub , Zarrok Hassan , Oudda Hassan 
Published: September 2024

Background:
The corrosion of Mild Steel (MS) in harsh acidic environments, such as
Hydrochloric acid (HCl), is a significant industrial issue with environmental consequences. Corrosion
inhibitors, particularly those containing heteroatoms and aromatic rings, are a proven method
for mitigating corrosion. Traditional methods for studying corrosion inhibitors often require resource-
intensive experiments.

Methods:
This study explores the use of Quantitative Structure-Property Relationship (QSPR) modeling,
a Machine Learning (ML) technique, to predict the inhibition efficiency of organic corrosion
inhibitors in HCl environments. Several ML models were employed: Linear Regression (LR), Random
Forest Regression (RF), Support Vector Regression (SVR), Multilayer Perceptron Regression
(MLP), and XGBoost Regression (XGB).

Results:
The investigation revealed that some models achieved exceptional predictive accuracy with
significantly reduced errors and high precision. These models offer a promising avenue for efficient
corrosion inhibitor design, reducing reliance on extensive experimentation.

Conclusion:
This study contributes to the advancement of corrosion science and materials engineering
by introducing innovative strategies for developing effective corrosion inhibitors using machinelearning-
driven QSPR models.
Tofacitinib-Induced Acute Pancreatitis in a Patient with Rheumatoid Arthritis: A Case Report and Review of the Literature
Authors: Boussaa Hiba , Hamdi Ons , Miladi Saoussen , Makhlouf Yasmine , Ben Abdelghani Kawther , Fazaa Alia , Laatar Ahmed 
Published: September 2024

Background:
Acute Pancreatitis (AP) is an uncommon complication that rarely occurs
during Rheumatoid Arthritis (RA). Among the varied etiologies of AP, Drug-induced Pancreatitis
(DIP) remains a rare entity and a rather challenging condition. A large panel of drugs
have been reported to cause pancreatitis; however, there are no cases of tofacitinib-induced pancreatitis
reported in the literature.

Case Presentation:
We have, herein, reported the case of a Tunisian 58-year-old woman with a
four-year history of RA who experienced two episodes of AP; the first one occurred on the second
day of a 3-day series of methylprednisolone intravenous injections, and the second episode
occurred on the sixth-day of tofacitinib administration. Each time, she presented acute abdominal
pain with characteristic radiation to the back. Symptoms resolved spontaneously once
the suspected drug was discontinued. In the event of a negative investigation, including abdominal
ultrasonography and magnetic resonance imaging, and assessment of albumin, calcemia,
triglyceridemia, serum ferritin, and IgG4 levels, DIP was the most likely diagnosis.

Conclusion:
Although DIP is still a rare condition, it remains serious with an increased risk of
mortality. We intended to alert clinicians that in addition to the known side effects of tofacitinib,
pancreatitis may be induced by this drug, especially in predisposed patients.
The Biological Effects of Soy Isoflavones against Myocardial Ischemia-reperfusion Injuries: A Systematic Review
Authors: Heidari-Soureshjani Saeid , jafari Negar , Masoumi Shahab , Abbasnezhad Mohsen , MT Sherwin Catherine 
Published: September 2024

Background:
Myocardial Ischemia-Reperfusion Injury (MIRI) is associated with adverse
cardiovascular outcomes that lead to the death of ischemic cardiomyocytes and, finally, dysfunction
of cardiac tissue.

Objectives:
This systematic review aims to comprehensively investigate and systematically review
the existing literature on the effects of soy isoflavones and their underlying mechanisms in mitigating
MIRI injuries.

Methods:
A systematic search was conducted in high-coverage scientific databases, including Web
of Science, MEDLINE/PubMed, Scopus, Embase, and Cochrane Library. On 6th December, 2023, an
extensive literature search was done using predefined search terms (According to MeSH terms) and
inclusion criteria. Any studies that investigated the effects of soy isoflavones on MIRI injuries were
included. Search strategy, screening of the publications, and data extraction were performed following
PRISMA guidelines 2020.

Results:
Diverse mechanisms underlying the cardioprotective effects of soy isoflavones against
MIRI include antioxidant properties, anti-inflammatory effects, enhanced mitochondrial function,
regulation of apoptosis pathways, improving angiogenesis effects, attenuating heart histological
changes, modulating factors that affect hemodynamic changes, and reducing Ca+2 overload. Although
most studies reported promising effects in reducing the complications of MIRI, a small number
of studies also showed no significant effect in this regard. Also, they did not report any specific
side effects from consuming isoflavones alone.

Conclusion:
The findings suggest that soy isoflavones as a complementary therapeutic strategy potentially
benefit MIRI outcomes and support their role in cardiovascular health. However, further
well-designed clinical trials are warranted to validate these findings and establish their clinical significance
in cardiovascular disease management.
Industry 4.0 in Aircraft Production, Maintenance, Repair, and Overhaul [MRO]: Investigating Use Cases and Associated Patent Landscape
Authors: Bhatia Vineet , Kumar Ajay , Sidharth Sumati , Dogra Namrata , Altarazi Faisal , Singh Jashanpreet 
Published: September 2024

Background:
The aerospace industry has been gradually adopting Industry 4.0 technologies,
such as the Internet of Things [IoT], big data analytics, and cyber-physical systems, to enhance
aircraft maintenance, repair, and overhaul [MRO] operations. These technologies have the
potential to improve operational efficiency, reduce costs, and enhance safety in the MRO sector.

Objective:
This study aims to analyze the current state of Industry 4.0 integration in aircraft
maintenance/MRO operations by examining relevant use cases and conducting a patent landscape
analysis. The primary objectives are to identify the key players, emerging trends, and technological
hotspots in this field, as well as to understand the challenges and opportunities associated with the
integration of Industry 4.0 in aircraft MRO.

Methods:
The research methodology involves a comprehensive literature review to identify and analyze
use cases of Industry 4.0 technologies in aircraft manufacturing and MRO operations. A systematic
approach was adopted to collect and analyze relevant patent data from various patent databases.
The search strategy involved the use of specific keywords related to Industry 4.0 technologies
and aircraft MRO. The retrieved patent documents were then subjected to rigorous analysis,
including bibliometric analysis, technological categorization, and patent landscape mapping.

Results:
The patent landscape analysis revealed a steadily increasing trend in patent filings related
to Industry 4.0 technologies in aircraft MRO. The major players in this field were identified, and
their patent portfolios were analyzed. The analysis of use cases also highlighted that key technological
areas, such as 3-D printing and digital twin technology, are attracting significant attention from
aircraft industry stakeholders.

Conclusion:
The analysis of patent landscapes in the field of aircraft maintenance, repair, and
overhaul [MRO] provides valuable insights into the current state, emerging trends, and future directions
within the industry. These insights are crucial for industry stakeholders, researchers, and policymakers
to make informed decisions regarding technology adoption, investment strategies, and
regulatory frameworks. In conclusion, the examination of patent landscapes serves as a foundational
tool for enhancing transparency, standardization, and reproducibility in research, enabling stakeholders
to navigate the complex landscape of Industry 4.0 in aircraft MRO effectively.
Facile Synthesis of a Nano Redox-Sensitive Castor Oil-Based Amphiphilic Macromolecule: An Assorted Anticancer Carrier in Doxorubicin Delivery
Authors: Saeedi Sara , Alavioon Seyed Iman , Nabid Mohammad Reza 
Published: September 2024

Background:
Cancer is the second most common cause of death worldwide, killing
more than 8 million people every year. The primary treatment is still restricted to conventional
chemotherapy; however, this method has some limitations. Drug delivery systems (DDSs) provide
the possibility to overcome these defects.

Objective:
The main object of the present report is to introduce the first amphiphilic macromolecule
deduced from vegetable oil as a stimulus-responsive drug delivery system.

objective:
The main object of this research is to introduce the first amphiphilic macromolecule deduced from vegetable oil as a stimuli-responsive drug delivery system.

Methods:
Initially, maleated castor oil was synthesized from the reaction of castor oil with 2-hydroxyethyl
disulfide. In the last step, a thiol-ene click reaction was carried out under thermal conditions.
The structure of the polyol was characterized by proton nuclear magnetic resonance (1HNMR)
and Fourier transform infrared spectroscopy (FT-IR). The average size, morphology,
CMC, drug loading drug release properties, and cytotoxicity of the nanocarrier were screened by
different analyses.

Results:
The dynamic light scattering and scanning electron microscopy revealed an appropriate
size (about 66 nm) and spherical morphology of nanoparticles, respectively. Doxorubicin was encapsulated
in polyol with a drug loading efficiency of 83%. in vitro MTT assays confirmed that
the micelles are biocompatible and nontoxic, while drug-loaded micelles possess high antitumor
activity in cancer cells.

Conclusion:
Some advantages of this carrier are its uncomplicated synthesis, stimulus responsiveness
based on vegetable oil, biocompatibility, good stability, and acceptable critical micelle concentration.
Hasta que la dignidad se haga costumbre. Cuidar con el corazón
Authors: Lorenzano Schifrin Sandra Silvina 
Published: September 2024

1.	Cuidar puede ser a veces una pequeña luz en la oscuridad, puede ser el modo de construir un mínimo asidero a la vida. Cuidar una ausencia. Cuidar con el corazón desgarrado. Sacar fuerzas del dolor para ganarle la batalla a las sombras. En un país sembrado de fosas clandestinas, de “cuerpos sin nombre y de nombres sin cuerpo”, 2 de hijas e hijos, madres y padres, hermanas y hermanos que nunca regresaron a casa, el cuidado de una última llamita de esperanza es también, y a pesar de todo, el cuidado de la vida. 2.	¿Cómo se cuenta el horror? ¿Cómo se habla de la violencia, de las muertes, de los desaparecidos? ¿Cómo se crea desde el desgarramiento? Estas preguntas que han estado en el centro de las reflexiones sobre la transmisión de la memoria en América Latina cobran nueva importancia en países que, como México, se encuentran sumergidos en uno de los periodos más violentos de su historia. ¿Cómo se cuenta este “fulgor de sangre”, como lo llama el poeta David Huerta en el poema “Sobre las muertas de Juárez”? Antes de entrar a algunas de las principales autoras, vale la pena que nos detengamos en el concepto de desaparición, tal como lo plantea una de las voces más autorizadas sobre el tema: Pilar Calveiro. 3.	La naturaleza, la maternidad, el compromiso son temas que se entretejen en esta malla sutil de memorias dolidas, encuentro y desencuentros con los ausentes. 1978, 2010 o 2020, la respuesta del Estado es similar: por acción o por omisión. Estamos aún lejos de poder construir esas tres columnas fundamentales de los derechos humanos: memoria, verdad, justicia. El documental es sensible y profundo. La ética, respetuosa de las palabras y los silencios de las víctimas, lo convierte en un conmovedor ejercicio político y amoroso.
Cultura Viva e o transbordamento de fronteira - entrevista com Célio Turino
Authors: Turino Célio , Lima Deborah Rebello , Rodrigues Luiz Augusto F. 
Published: September 2024

Entrevista com Célio Turino concedida aos pesquisadores Deborah Rebello Lima, da UFPR, e Luiz Augusto F. Rodrigues, da UFF, realizada em 23 de abril de 2024.
IMPLEMENTASI SKEMA PEMBIAYAAN PADA HAK CIPTA DALAM EKONOMI KREATIF DIHUBUNGKAN DENGAN ASAS ALTER EGO, TEORI PENGHARGAAN DAN TEORI HASIL KERJA
Authors: Khoirunisa Qorina , Mayana Ranti Fauza , Muchtar Helitha Novianty 
Published: September 2024

Peraturan Pemerintah (PP) Nomor 24 Tahun 2022 tentang Pelaksanaan UU Ekraf menyebutkan bahwa terdapat skema pembiayaan yang diberikan kepada para pelaku ekonomi kreatif berbasiskan kekayaan intelektual (KI) termasuk didalamnyamelalui pemanfaatan Hak Cipta yang bernilai ekonomi. Skema pembiayaan dalam konteksekonomi kreatif dapat mencakup berbagaipendekatan seperti pembiayaan modal ventura, pembiayaan kredit usaha rakyat, pembiayaanmikro, pembiayaan berbasis risiko (PembiayaanModal Kerja dan Investasi). Sebuah ciptaanmemiliki cerminan dari penciptanya (alter ego) dan hal ini tidak dapat dialihkan karna termasuk sebagai hak moral yang melekat mutlak pada penciptanya. Jika skema pembiayaan menjadikankarya dari pencipta sebagai objek jaminan, makaperlu untuk diteliti apakah dalam terjadinyawanprestasi, objek tersebut akan sepenuhnyaberpindah tangan kepada kreditur ataukah hanyasebatas sampai kreditur memenuhi kewajibannya. Proses labour yang membuat hak kekayaan intelektual pada pencipta atau penemu hingga menciptakan suatu karya. Maka sejauh mana asas alter ego, teori reward dan teori labour dapat diimplementasikan dalam skema pembiayaan pada ekonomi kreatif. Metode penelitian yang digunakan oleh penulis dalam riset ini adalah yuridis normatif. Dari penelitian ini didapatkan kesimpulan pertama, tiap hak cipta dapat memiliki nilai yang sangat berbeda karena faktor alter ego. maka semestinyadiberi keleluasaan bagi pencipta untuk dapat bebasmemilih dalam mendapatkan fasilitaspembiayaan,bukan hanya dalam sistem kreditdimana objek ciptaan dapat terancam dialihkan jika pencipta berpotensi gagal bayar. Kedua, Pemenuhan teori reward dalam konteks ekonomiuntuk hak cipta belum sepenuhnya terlaksana. Salah satunya karena pilihan terbatas pendanaanyang dapat diberikan kepada pencipta hanyadalam bentuk kredit. Pemberian reward kepadapencipta masih hanya sebatas konsep teoritis dan tertulis dalam peraturan, namun belum dapatdilaksanakan secara menyeluruh dengan benar-benar menghargai pencipta.
Studi Pengaruh Intentional Learning dengan Metode Writing-to-Learn pada Kemampuan Recall
Authors: Saragih Josua Windy , Noer Afra Hafny , Pebriani Lucia Voni 
Published: September 2024

Penelitian ini dimaksudkan untuk membuktikan pengaruh intentional learning dengan metode writing-to-learn (WTL) pada kemampuan recall. Keberadaan prompt sebagai operasionalisasi WTL pada intentional learning berfungsi sebagai pengarah intensi kepada proses atensi yang lebih terfokus serta kemampuan recall yang meningkat. Penempatan instruksi menulis dan penggunaan writing prompt yang tepat dapat mengarahkan pada kegiatan belajar yang lebih efektif. Dilakukan eksperimen terhadap penempatan writing prompt dengan mengukur kemampuan recall hasil belajar. Terdapat 64 partisipan mahasiswa Psikologi yang dibagi ke dalam 2x2 nonequivalent between subject design, yaitu menulis “dengan prompt” dan “tanpa prompt” serta diberi tahu bahwa terdapat kegiatan menulis “sebelum” dan “sesudah” menonton video pembelajaran. Berdasarkan uji statistik Kruskal-Wallis, ditemukan bahwa terdapat perbedaan signifikan antarkelompok eksperimen (H(3) = 18.391, p < .00). Terdapat perbedaan signifikan pada kemampuan recall pada kedua kelompok menulis “dengan prompt” (z = -24.267, p < .05) serta pada kedua kelompok menulis “tanpa prompt” (z = 13.611, p < .05). Ditemukan bahwa perbedaan penempatan pemberitahuan kegiatan menulis serta penggunaan prompt dalam tulisan memengaruhi atensi partisipan yang berpengaruh pada kemampuan recall. Hal ini membuktikan bahwa terdapat pengaruh intentional learning dengan metode WTL pada kemampuan recall. Namun, prompt yang kurang familiar memunculkan orienting response sehingga hasil dari eksperimen ini perlu dibahas lebih lanjut.
Penerapan Lean Warehousing Pada Gudang Bahan Baku Industri Farmasi PT XYZ
Authors: Diina Tresnafuty Rasyiida , Sriwidodo Sriwidodo , Sylvia Nurrasjid Evi , Kustiyawan Iwa 
Published: September 2024

Persaingan di dunia Industri pada era modern ini memicu para perusahaan untuk meningkatkan daya saing dan kualitas produk sebagai pemenuhan kepuasan pelanggan. Gudang dalam Industri Farmasi berperan dalam menjaga keberhasilan dan kelancaran rantai pasok produk. Setiap aktivitas yang dilakukan di gudang merupakan hal yang sangat penting bagi Industri Farmasi terutama pada aspek penyimpanan dan pengiriman. Gudang bahan baku merupakan tempat penyimpanan bahan baku yang akan digunakan untuk proses produksi, maka dari itu pengelolaan barang persediaan yang tidak efektif dan efisien dapat dilihat dari adanya pemborosan atau waste pada proses di gudang. Penelitian ini bertujuan untuk meningkatkan efisiensi aktivitas pergudangan melalui identifikasi pemborosan (waste) pada kegiatan di gudang bahan baku. Penelitian dilakukan menggunakan tool Value Stream Mapping dan Process Activity Mapping. Setelah waste teridentifikasi, maka tahapan selanjutnya adalah mencari akar permasalahan menggunakan fishbone diagram untuk selanjutnya dibuat rencana usulan perbaikan berupa Future Value Stream Mapping. Diketahui waste yang dominan terjadi adalah waiting dan motion. Usulan perbaikan yang dapat dilakukan yaitu dengan melengkapi informasi dimensi lokasi penyimpanan pada sistem ERP serta peningkatan kesadaran operator dalam menerapkan SOP.
Testing of Daylighting and Heat Load Parameters in Different Design Types of Dairy Cow Housing
Authors: Balková Milada , Lendelová Jana , Karandušovská Ingrid , Žitňák Miroslav 
Published: September 2024

Abstract
The aim of the work was to test the level of daylight conditions and the heat load of animals in the summer season in two identically oriented dairy barns with different construction and material solutions. Measurements were carried out in the same farm and at the same time. A classic massive building – reconstructed barn (RB) for 158 dairy cows with a volume of 34.3 m3 per animal supplemented in summer by motor ventilation (522.15 m3 per animal, total 82,500 m3·h−1) had an indoor daylight factor DF below the limit DFavg, int
= 0.21% (against the recommended DF = 1% for housing dairy cows). In the external feeding alley, which was screened by a shelter and an adjacent building, lighting conditions were compliant with DFavg, ext
= 4.02%. However, the level of heat load as measured by indices was above the limit (THIavg, int
= 84.65) despite the motor ventilation used; in the outdoor feeder THIavg, ext
= 81.63, against the recommended stress-free level THI = 72. Similarly, according to the ETIC assessment, the results were deficient ETICavg, int
= 26.16 and in the outdoor feed ETICavg, ext
= 25.24 against the recommended level of ETIC = 20. The second building, a new barn (NB) for 444 dairy cows was a new large-cubicle indoor structure with 82.53 m3 per animal, with a translucent roof (37.87% of the total 4,927.6 m2 was of translucent polycarbonate triple-pipe roofing). This amount of translucent elements together with large window openings of a total area of 879.6 m2 was also reflected in the values of the daylight factor DFavg, int
= 7.59%. The level of heat load was not significantly lower compared to a massive RB with motor ventilation over a double row of bunks (fans with a total capacity of 82,500 m3·h−1). In NB, no animal cooling features were activated, but technically and spatially they were easily solvable (whether economical ventilation systems with laminar flow, precisely controlled sprinkling of animals, or another combination of evaporative and flow solutions). These efficient types of cooling would be almost impossible to deploy in RB or only with a special renovation of the building, which would be comprehensively costly.
Virtual Simulation Modeling as a Key Element of Warehouse Location Optimization Strategy
Authors: Krynke Marek 
Published: September 2024

Abstract
This article examines the utilization of computer simulation techniques for optimizing warehouse locations, an essential component of efficient supply chain management. The study employs a detailed simulation model built using FlexSim software to analyze various decision-making scenarios and identify the optimal warehouse locations while considering market demand for different products. The model integrates a finite set of decision variables and constraints specific to the logistics problem, offering a structured approach to evaluate alternative strategies. Key stages in the development of the simulation model are outlined, including the definition of input parameters, the execution of simulations, and the interpretation of results. The findings demonstrate that virtual simulation modeling significantly enhances decision-making processes by providing precise insights into the interactions within the distribution network. Additionally, the use of simulation results in considerable time and cost savings by reducing the need for costly physical trials. This research underscores the effectiveness of computer simulation in optimizing warehouse locations, contributing to improved supply chain performance and operational efficiency.
Implementation of the FMEA Method as a Support for the HACCP System in the Polish Food Industry
Authors: Szczyrba Anna , Ingaldi Manuela 
Published: September 2024

Abstract
The main objective of the work was to assess the possibility of using and implementing the FMEA method as an effective support for the HACCP system in a selected food industry enterprise. The research entity was a food enterprise located in central Poland and the subject of the research was canned meat with gravy in glass jars and their production line. In the study, programs such as draw.io, Excel, and Statistica were used. The study was conducted based on interviews with company employees, value stream analysis and nonconformance reports. During the site visit, an assessment of the company’s infrastructure was also carried out to evaluate the possibility of implementing the FMEA method. Data analysis showed that in the examined company there are non-compliances with varying degrees of impact on the final quality of the product or on the production process of this product. The analysis of the company’s infrastructure, in turn, confirms that it is possible to integrate the HACCP system with the FMEA method. The results indicate that the synergy of HACCP and FMEA will bring benefits to the company in the form of improved risk management, quality control and safety in food production. The results of this study suggest that implementing such a connection may bring many, various benefits to food companies not only in Poland but also in another countries.