bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of well‐field configuration on contaminant mass removal and plume persistence for homogeneous versus layered systems
Authors: Guo Zhilin , Brusseau Mark L. 
Published: November 2017

AbstractA three‐dimensional numerical model was used to simulate the impact of different well‐field configurations on pump‐and‐treat mass removal efficiency for large groundwater contaminant plumes residing in homogeneous and layered domains. Four well‐field configurations were tested, Longitudinal, Distributed, Downgradient, and natural gradient (with no extraction wells). The reductions in contaminant mass discharge (CMDR) as a function of mass removal (MR) were characterized to assess remediation efficiency. Systems whose CDMR‐MR profiles are below the 1:1 relationship curve are associated with more efficient well‐field configurations. For simulations conducted with the homogeneous domain, the CMDR‐MR curves shift leftward, from convex‐downward profiles for natural gradient and Longitudinal to first‐order behaviour for Distributed, and further leftward to a sigmoidal profile for the Downgradient well‐field configuration. These results reveal the maximum potential impacts of well‐field configuration on mass‐removal behaviour, which is attributed to mass‐transfer constraints associated with regions of low flow. In contrast, for the simulations conducted with the layered domain, the CMDR‐MR relationships for the different well‐field configurations exhibit convex‐upward profiles. The nonideal mass‐removal behaviour in this case is influenced by both well‐field configuration and back diffusion associated with low‐permeability units.
Nutrients intake, and serum calcium and phosphorus levels: An evidence‐based study
Authors: Jafari Giv Zahra , Avan Amir , Hamidi Farshid , Tayefi Maryam , Khayyatzadeh Sayyed Saeid , Javandoost Ali , Nematy Mohsen , Ferns Gordon A. , Mobarhan Majid Ghayour 
Published: November 2017

IntroductionDietary calcium and phosphorus appear to be important determinants of dyslipidemia and hypertension. We have investigated (1) the prevalence of hypocalcemia and hypophosphatemia in an Iranian population, and (2) the association between nutrient's intake and serum levels of calcium and phosphorus.MethodsA total of 908 individuals were enrolled using a stratified‐cluster sampling method from the Mashhad stroke and heart atherosclerosis disorder (MASHHAD) study. Dietplan6 software was used for 24‐hour recalls and food frequency questionnaire to investigate macro‐ and micronutrient intakes of our population, followed by univariate analysis for evaluation of the association of dairy consumption with serum calcium and phosphorus.ResultsWe observed that the mean dietary Ca intake was 862.4 mg/d (672.7‐1052) for men and 864.2 mg/d (604.5‐1123) for women in our population, which is lower than the dietary reference intake for Ca. Moreover, a significant relationship was detected between serum calcium level and dietary intakes of saturated fatty acids, copper, iodine, sucrose, potato, and juices. Of note, we observed a negative association between copper intake, and serum Ca (P˂.01). Also, a significant association was found between serum phosphorus levels and dietary intakes of chicken meat and fresh fruits. Interestingly, we observed an inverse relationship between tea and Ca/P ratio (eg, ‐r=.098; P=.02).ConclusionWe found that the dietary intake of Ca was not sufficient in our population and was associated with the dietary intake of some macro‐ and micronutrient, supporting further investigation on clinical impact of this condition on calcium/phosphorus deficiency related diseases.
Facile and versatile strategy to prepare magnetic molecularly imprinted particles based on the coassembly of magnetic nanoparticles and amphiphilic random copolymers
Authors: Zhu Lili , Cao Yuhua , Ni Xinjiong , You Aimei , Cao Guangqun 
Published: November 2017

AbstractMagnetic molecularly imprinted polymer nanoparticles for bisphenol A were prepared by coassembling magnetic nanoparticles and amphiphilic random copolymers. Under optimized conditions, bisphenol A as template molecules, magnetic molecularly imprinted polymer particles with regular morphology, small size, good monodispersity, and high content of OA‐Fe3O4 were prepared by the coassembly method using P(MMA‐co‐MAA) with monomer ratio of 9:1. These magnetic molecularly imprinted polymer particles could be rapidly collected by an external magnet within 1 min. The saturated adsorption capacity of the magnetic molecularly imprinted polymer for bisphenol A was 201.5 mg/g, and the imprinting factor was 2.5. The separation factors for bisphenol A to β‐estradiol, estriol, and diethylstilbestrol was 3.1, 2.9, and 3.7, respectively. Unlike assembling amphiphilic copolymer in the selective solvent, the coassembly process was simple and rapid. Therefore, the present work provided a facile and versatile approach to construct magnetic molecularly imprinted polymer nanoparticles under mild conditions.
Acoustic Process Control for Laser Material Processing
Authors: Fischer Balthasar , Rohringer Wolfgang , Panzer Nils , Hecker Sebastian 
Published: November 2017

AbstractListening to an industrial process can reveal relevant information. As a complementary approach to optical process surveillance, monitoring the acoustic emissions is a promising alternative. Yet, acoustic detectors have not been extensively established in process control, one reason being their limited frequency bandwidth. Overcoming the disadvantages of existing microphones, a novel laser‐based acoustic sensor opens new possibilities in industrial acoustic process monitoring.
Longitudinal analyses of adoptive parents’ expectations and depressive symptoms
Authors: Foli Karen J. , Lim Eunjung , South Susan C. 
Published: November 2017

ABSTRACTGrounded in a theoretical model specific to adoptive parents, we examined the relationship between parental expectations and depressive symptoms across time. Assessments of 129 adoptive parents of 64 children were performed at three time points before and after placement of an adopted child with the family: 4–6 weeks pre‐placement and 4–6 weeks and 5–6 months post‐placement. Expectations were assessed in four dimensions: expectations of self as parents, of the child, of family and friends, and of society. Depressive symptoms were assessed with the Center for Epidemiologic Studies‐Depression scale. Associations between parental expectations and depressive symptoms were analyzed, and longitudinal multilevel modeling was conducted to explore influences on expectations over time. Parental expectations changed from pre‐ to post‐placement. With the exception of expectations of self as parent, adoptive parents’ pre‐adoption expectations were affirmed in the post‐adoption time periods. In each expectation dimension, higher affirmation of expectations was correlated with decreased depressive symptoms before and after placement of a child. While parental expectations are not unique to adoptive parents, the essence and characteristics of certain expectations are unique to these parents. When working with adoptive parents, nurses who care for families should assess expectations both pre‐ and post‐placement with awareness of their relationship to depressive symptoms.
Prenatal diagnosis and prognosis of isolated subependymal cysts: A retrospective cohort study
Authors: Yang Mengmeng , Jiang Ying , Chen Qinqing , Lv Min , Luo Qiong 
Published: November 2017

AbstractObjectiveThe objective of this study was to investigate the significance of prenatal diagnosis of subependymal cysts (SEC). Diagnoses were made by brain ultrasonography (bUS) and confirmed by fetal brain magnetic resonance imaging (MRI).MethodsWe reviewed all the cases of isolated SEC diagnosed antenatally in our center from January 1, 2014, to December 31, 2015, and confirmed by fetal MRI. We followed up their evolution throughout pregnancy and the neonatal neurodevelopment at 3, 6, and 12 months using the Gesell Developmental Schedule.ResultsAmong the 91 cases in the cohort, 74 were bilateral and 17 unilateral. The SEC were significantly smaller in unilateral than bilateral cases (P < .001). Among the 35 cases with repeated bUS, SEC remained stable or decreased in size with advancing gestational age in 86% of cases. After excluding terminations of pregnancy (n = 13), neurodevelopment was normal in 75/78 (96%) cases with developmental quotient ≧85.ConclusionIsolated SEC are usually a benign finding. Accurate diagnosis is important to differentiate SEC from other pathologic brain conditions with a combination of brain ultrasonography and MRI.
Has noninvasive prenatal testing impacted termination of pregnancy and live birth rates of infants with Down syndrome?
Authors: Hill Melissa , Barrett Angela , Choolani Mahesh , Lewis Celine , Fisher Jane , Chitty Lyn S. 
Published: November 2017

AbstractBackgroundImplementation of noninvasive prenatal testing (NIPT) as a highly accurate aneuploidy screening test has raised questions around whether the high uptake may result in more terminations of pregnancies and fewer births of children with Down syndrome (DS).AimThe aim of the study was to investigate the impact of NIPT on termination and live birth rates for DS.MethodsLiterature reporting pregnancy outcomes following NIPT was reviewed. Termination rates were calculated for women with a high‐risk NIPT result for DS. Two audits of pregnancy outcomes where NIPT indicated DS were conducted in the United Kingdom and Singapore.ResultsFourteen studies from the United States, Asia, Europe, and the United Kingdom were included in the review. Live births of children with DS were reported in 8 studies. Termination rates following NIPT were unchanged or decreased when compared to termination rates prior to the introduction of NIPT. Audits found 15 of 43 women in the United Kingdom and 2 of 6 in Singapore continued pregnancies following a high‐risk NIPT result.ConclusionsTermination rates following the detection of DS by NIPT are unchanged or decreased compared to historical termination rates. Impact on live birth rates may be minimal in settings where termination rates fall. Population‐based studies are required to determine the true impact.
Tightening behaviour of preloaded stainless steel bolting assemblies
Authors: Stranghöner Natalie , Jungbluth Dominik , Abraham Christoph , Söderman Anders 
Published: November 2017

AbstractPreloaded bolting assemblies made of stainless steel are currently not permitted in steel structures due to the unknown viscoplastic deformation behaviour as well as the unknown tightening behaviour and tightening procedures for these kinds of bolting assemblies. Nonetheless, the construction industry wishes to carry out these types of connections in special cases, e.g. when special requirements exist with regard to corrosion resistance or for architectural reasons. Generally, the tightening behaviour of carbon steel HR and HV bolting assemblies according to EN 14399‐3 and ‐4 cannot simply be transferred uncritically to stainless steel bolting assemblies due to several reasons. Within the scope of the European RFCS research project SIROCO, extensive investigations are currently being conducted on the tightening and preloading behaviour of EN ISO 4014 and EN ISO 4017 bolting assemblies made of austenitic and duplex stainless steels. First results from this project show that a targeted tightening of such assemblies is in principle possible. Specified preloading levels, e. g. Fp,C* and Fp,C, can be achieved with sufficient reliability using suitable lubricants. Herewith, it is possible to define feasible tightening procedures. Furthermore, it could be shown that these bolting assemblies show sufficient ductility and galling of the assemblies can be for sure avoided. The present paper provides an initial insight into the results of the project.
Optimization of the test procedure for slip factor tests according to EN 1090‐2
Authors: Stranghöner Natalie , Afzali Nariman , de Vries Peter , Glienke Ralf , Ebert Andreas 
Published: November 2017

AbstractSlip‐resistant connections are always used when slip and deformation in a bolted connection must be avoided at all costs, e.g. in radio masts and bridges. For some popular surface treatments, slip factors are given in EN 1090‐2, the execution standard for steel structures. For those surface conditions not considered in EN 1090‐2, the slip factor can be determined experimentally according to Annex G of EN 1090‐2. By reviewing slip factor values obtained with the Annex G test procedure and reported in the literature, it becomes obvious that in most cases the slip factors achieved experimentally are not comparable for identical surface conditions. This is potentially caused by different interpretations of the Annex G slip test procedure. As the slip factor is one of the main parameters influencing the bearing capacity of slip‐resistant connections, its determination should be on the safe side and not dependent on the various interpretation possibilities of the test procedure itself. For this reason, the optimization of the Annex G test procedure was thoroughly investigated in the European RFCS research project SIROCO, with the final objective being to enhance its reliability. The focus was on investigating the various test parameters such as type of preload measurement, ascertaining the possible slip planes, test speed, position of slip measurement, clamping length, preload level, evaluation of critical slip load and the performance of the extended creep test. The results achieved in these investigations have already been partly implemented in the revision of the current draft version of EN 1090‐2.
Methylisothiazolinone may induce cell death and inflammatory response through DNA damage in human liver epithelium cells
Authors: Park Eun‐Jung , Kim Sanghwa , Chang Jaerak 
Published: November 2017

AbstractMethylisothiazolinone (MIT) is a powerful biocide and preservative, which is widely used alone or in a 1:3 ratio with methylchloroisothiazolinone (MCIT) under the trade name of Kathons in the manufacture of numerous personal and household products. Considering that Kathons injected intravenously is distributed in the blood and then in the liver, we explored the toxic mechanism of MIT on human liver epithelium cells. At 24 h after exposure, MIT bound to the plasma membrane and the inner wall of vacuoles in the cells, and rupture of the cell membrane and nuclear envelop, autophagosome‐like vacuoles formation and mitochondrial damage were observed. Cell viability dose‐dependently decreased accompanying an increase of apoptotic cells, and the level of LDH, NO, IFN‐gamma, IL‐10 and IL‐8, but not IL‐1β, significantly increased in the culture media of cells exposed to MIT. Additionally, expression of autophagy‐, membrane damage‐ and apoptosis‐related proteins was notably enhanced, and the produced ATP level dose‐dependently decreased with the reduced mitochondrial activity. Furthermore, the increased DNA damage and the decreased transcription activity were observed in MIT‐treated cells. Meanwhile, the intracellular ROS level did not show dose‐dependent change at the same time‐point. Then we explored the role of autophagy in MIT‐induced cytotoxicity by inhibiting or inducing the autophagic signal. Intriguingly, no additional cell death induced by autophagic modulation occurred when MIT was treated. Taken together, we suggest that MIT may induce multiple pathways of cell death and inflammatory response through DNA damage caused by rupture of the nuclear envelope.
Through the Sliding Glass Door: #EmpowerTheReader
Authors: Johnson Nancy J. , Koss Melanie D. , Martinez Miriam 
Published: November 2017

AbstractThis article seeks to complicate the understanding of Bishop's () metaphor of mirrors, windows, and sliding glass doors, with particular emphasis on sliding glass doors and the emotional connections needed for readers to move through them. The authors begin by examining the importance of the reader and the characters he or she meets. Next, the authors extend Bishop's metaphor by exploring the role of readers’ emotional connections to texts and characters. The authors then make recommendations for selecting appropriate books, linking books thematically, and guiding readers in ways to respond. They conclude with a call to action for teachers to consider their responsibility to #EmpowerTheReader.
Microaerophilic alkane degradation in Pseudomonas extremaustralis: a transcriptomic and physiological approach
Authors: Tribelli Paula M , Rossi Leticia , Ricardi Martiniano M , Gomez-Lozano Maria , Molin Søren , Raiger Iustman Laura J , Lopez Nancy I 
Published: November 2017

Abstract
Diesel fuel is one of the most important sources of hydrocarbon contamination worldwide. Its composition consists of a complex mixture of n-alkanes, branched alkanes and aromatic compounds. Hydrocarbon degradation in Pseudomonas species has been mostly studied under aerobic conditions; however, a dynamic spectrum of oxygen availability can be found in the environment. Pseudomonas extremaustralis, an Antarctic bacterium isolated from a pristine environment, is able to degrade diesel fuel and presents a wide microaerophilic metabolism. In this work RNA-deep sequence experiments were analyzed comparing the expression profile in aerobic and microaerophilic cultures. Interestingly, genes involved in alkane degradation, including alkB, were over-expressed in micro-aerobiosis in absence of hydrocarbon compounds. In minimal media supplemented with diesel fuel, n-alkanes degradation (C13–C19) after 7 days was observed under low oxygen conditions but not in aerobiosis. In-silico analysis of the alkB promoter zone showed a putative binding sequence for the anaerobic global regulator, Anr. Our results indicate that some diesel fuel components can be utilized as sole carbon source under microaerophilic conditions for cell maintenance or slow growth in a Pseudomonas species and this metabolism could represent an adaptive advantage in polluted environments.
Correction to: A Micellar Liquid Chromatographic Method for the Determination of Azosemide in Solubilized System
Authors: Malvia Hitesh , Kumar Ashok , Sharma Pratibha , Mishra Ritesh 
Published: November 2017

AbstractIn the original publication of the article, the corresponding author's name was incorrectly published. The corresponding author's name should appear as Ashok Kumar.
Extracellular vesicles: novel vehicles in herpesvirus
infection
Authors: Liu Lingzhi , Zhou Quan , Xie Yan , Zuo Lielian , Zhu Fanxiu , Lu Jianhong 
Published: November 2017

AbstractHerpesviruses are remarkable pathogens that have evolved multiple mechanisms to
evade host immunity, ensuring their proliferation and egress. Among these
mechanisms, herpesviruses utilize elaborate extracellular vesicles, including
exosomes, for the intricate interplay between infected host and recipient cells.
Herpesviruses incorporate genome expression products and direct cellular products
into exosomal cargoes. These components alter the content and function of exosomes
released from donor cells, thus affecting the downstream signalings of recipient
cells. In this way, herpesviruses hijack exosomal pathways to ensure their survival
and persistence, and exosomes are emerging as critical mediators for virus
infection-associated intercellular communication and microenvironment alteration. In
this review, the function and effects of exosomes in herpesvirus infection will be
discussed, so that we will have a better understanding about the pathogenesis of
herpesviruses.
Lattice Boltzmann simulations of low-Reynolds-number flows past fluidized spheres: effect of inhomogeneities on the drag force
Authors: Rubinstein Gregory J. , Ozel Ali , Yin Xiaolong , Derksen J. J. , Sundaresan Sankaran 
Published: November 2017

The formation of inhomogeneities within fluidized beds, both in terms of the particle configurations and flow structures, have a pronounced effect on the interaction force between the fluid and particles. While recent numerical studies have begun to probe the effects of inhomogeneities on the drag force at the particle scale, the applicability of prior microscale constitutive drag relations is still limited to random, homogeneous distributions of particles. Since an accurate model for the drag force is needed to predict the fluidization behaviour, the current study utilizes the lessons of prior inhomogeneity studies in order to derive a robust drag relation that is both able to account for the effect of inhomogeneities and applicable as a constitutive closure to larger-scale fluidization simulations. Using fully resolved lattice Boltzmann simulations of systems composed of fluid and monodisperse spherical particles in the low-Reynolds-number (Re) regime, the fluid–particle drag force, normalized by the ideal Stokes drag force, is found to significantly decrease, over a range of length scales, as the extent of inhomogeneities increases. The extent of inhomogeneities is found to most effectively be quantified through one of two subgrid-scale quantities: the scalar variance of the particle volume fraction or the drift flux, which is the correlation between the particle volume fraction and slip velocity. Scale-similar models are developed to estimate these two subgrid measures over a wide range of system properties. Two new drag constitutive models are proposed that are not only functions of the particle volume fraction and the Stokes number ($St$), but also dependent on one of these subgrid measures for the extent of inhomogeneities. Based on the observed, appreciable effect of inhomogeneities on drag, these new low-Re drag models represent a significant advancement over prior constitutive relations.
Comparison of Different Ranking Methods in Wine Tasting
Authors: Cao Jing , Stokes Lynne 
Published: November 2017

AbstractIn this paper, we compare three ranking methods in wine tasting in terms of their respective accuracy levels. The first two are the original-score average and rank average, which are conventional methods in practice. The third is a relatively new ranking method called Shapley ranking. It is a game-theory-based ranking method, whereby judges are required not to rank order or score all the wines but only to choose a subset that they find meritorious. A simulation study is designed, wherein the data-generating scheme mimics how the real wine-tasting data are produced. We also consider two criteria in the comparison: the squared-error loss, which is a suitable measure when accurate ranking of all wines is of interest; and the percentile loss, which only considers whether the wines are correctly put in a certain subset. The main conclusion from our study is that the ranking based on score average is generally more accurate than that based on rank average. Shapley ranking, with the consideration that it puts less burden on judges in wine tasting, may outperform the other methods in certain conditions. (JEL Classifications: C11, C15, D72, D81)