bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translanguaging practices during storytelling with the app iTEO in preschools
Authors: Kirsch Claudine 
Published: June 2017

Abstract
Whilst contributing to a person’s language, cognitive and personal development and whilst a common practice in the daily lives of bilinguals, translanguaging is rarely observed in educational institutions. The present paper examines the situations and the ways in which preschool children in trilingual Luxembourg translanguage during collaborative storytelling on iTEO, an iPad app which allows for the recording and editing of oral language. Currently 62.4% of children do not speak Luxembourgish on school entry. Language policies focus on the learning of Luxembourgish. This, the small class sizes and the absence of peers with similar language backgrounds may limit the opportunities for translanguaging. The present qualitative, longitudinal study takes a mixed-method approach. The findings show that the 5 focus children in preschool translanguaged frequently, in different ways and for a range of purposes, while drawing on features of several languages. The process of translanguaging depended on the individual child and on contextual factors. We argue that storytelling on iTEO opens up safe translanguaging spaces that contribute to inclusive multilingual pedagogies.
Translanguaging pedagogy in multilingual early childhood classes
Authors: Andersen Katja N. 
Published: June 2017

Abstract
This paper investigates translanguaging practices and pedagogy with very young children in the trilingual country of Luxembourg. Recent research has shown that in early childhood education in Luxembourg there is a focus on Luxembourgish to the exclusion of other languages and that this appears to exclude children with foreign language backgrounds from everyday institutional life. Our research asks how and in which forms can a translanguaging pedagogy offer young multilingual children opportunities to engage in literacy practices. Our empirical qualitative pilot study carried out among children aged 2 to 6 in Luxembourgish early childhood programs clarifies forms of translanguaging when instruction is accompanied by pictures and reading in German. The findings suggest that gesture and body language are part of translanguaging, providing multiple resources that enable the young multilingual learner to make meaning.
The multilingual turn in FL education
Authors: Spinelli Barbara 
Published: June 2017

AbstractThe study reported in this article aimed at exploring the impact of pluralistic pedagogy practices on L3/Ln learners’ reading and writing abilities in a multilingual classroom. Students attended an Intensive Elementary Italian course. The prerequisite to register for this course was knowledge of at least one other Romance Language or previous exposure to the Italian language. Specifically, the investigation examined whether and how the plurilingual system of these learners could affect the development of the language abilities mentioned above. Quantitative and qualitative data were collected using questionnaires and more traditional tests: a writing test and a reading test with a gradual increase in complexity. The results showed that a plurilingual pedagogy facilitated positive interlingual transfers, and consequently the development of both language abilities, particularly writing. It also appeared that connections between reading and writing were established, that is, the improvement of students’ writing skills affected reading comprehension and not vice versa. The development of these language abilities also seemed to be affected by other variables such as the proficiency level of languages present in learners’ plurilingual repertoire. To conclude, possible implications for language teaching/learning are discussed.
Co-constructing a translanguaging space
Authors: Tsuchiya Keiko 
Published: June 2017

AbstractTranslanguaging is an emergent concept in bi/multilingualism and language education. It refers to discursive practices where multiple languages are used by plurilingual individuals as an integrated linguistic repertoire (García and Li Wei 2014). This study focuses on the use of translanguaging in a group discussion in a Content and Language Integrated Learning (CLIL) classroom at a Japanese university, where Japanese students and one Arabic student talked in three Japanese and English as a Lingua Franca (ELF). The study examined why (the function) and how (the process) the participants translanguaged from Japanese to ELF in this particular context. During a forty-minute discussion, the participants spoke in Japanese most of the time, and ELF was used for less than ten minutes in total, especially between a Japanese and an Arabic speaker. Based onGumperz (1982)andKlimpfinger (2007), four functions of translanguaging were identified: (1) addressee specification, (2) assertion, (3) clarification and (4) appealing for linguistic assistance. The process of translanguaging was also examined in relation to turn-taking structure. The results show that the use of response tokens in ELF and meta-linguistic comments functioned as cues for translanguaging. In so doing, the participants co-constructed a translanguaging space.
Pilot KaVA monitoring on the M 87 jet: Confirming the inner jet structure and superluminal motions at sub-pc scales
Authors: Hada Kazuhiro , Park Jong Ho , Kino Motoki , Niinuma Kotaro , Sohn Bong Won , Ro Hyun Wook , Jung Taehyun , Algaba Juan-Carlos , Zhao Guang-Yao , Lee Sang-Sung , Akiyama Kazunori , Trippe Sascha , Wajima Kiyoaki , Sawada-Satoh Satoko , Tazaki Fumie , Cho Ilje , Hodgson Jeffrey , Lee Jeong Ae , Hagiwara Yoshiaki , Honma Mareki , Koyama Shoko , Oh Junghwan , Lee Taeseak , Yoo Hyemin , Kawaguchi Noriyuki , Roh Duk-Gyoo , Oh Se-Jin , Yeom Jae-Hwan , Jung Dong-Kyu , Oh Chungsik , Kim Hyo-Ryoung , Hwang Ju-Yeon , Byun Do-Young , Cho Se-Hyung , Kim Hyun-Goo , Kobayashi Hideyuki , Shibata Katsunori M. 
Published: June 2017

Abstract
We report the initial results of our high-cadence monitoring program on the radio jet in the active galaxy M 87, obtained by the KVN and VERA Array (KaVA) at 22 GHz. This is a pilot study that preceded a larger KaVA–M 87 monitoring program, which is currently ongoing. The pilot monitoring was mostly performed every two to three weeks from 2013 December to 2014 June, at a recording rate of 1 Gbps, obtaining data for a total of ten epochs. We successfully obtained a sequence of good quality radio maps that revealed the rich structure of this jet from ≲1 mas to 20 mas, corresponding to physical scales (projected) of ∼0.1–2 pc (or ∼140–2800 Schwarzschild radii). We detected superluminal motions at these scales, together with a trend of gradual acceleration. The first evidence for such fast motions and acceleration near the jet base were obtained from recent VLBA studies at 43 GHz, and the fact that very similar kinematics are seen at a different frequency and time with a different instrument suggests that these properties are fundamental characteristics of this jet. This pilot program demonstrates that KaVA is a powerful VLBI array for studying the detailed structural evolution of the M 87 jet and also other relativistic jets.
The CGRP receptor antagonist BIBN4096 inhibits prolonged meningeal afferent activation evoked by brief local K+stimulation but not cortical spreading depression-induced afferent sensitization but not cortical spreading depression-induced afferent sensitization
Authors: Zhao Jun , Levy Dan 
Published: June 2017

AbstractIntroductionCortical spreading depression (CSD) is believed to promote migraine headache by enhancing the activity and mechanosensitivity of trigeminal intracranial meningeal afferents. One putative mechanism underlying this afferent response involves an acute excitation of meningeal afferents by cortical efflux of K+and the ensuing antidromic release of pro-inflammatory sensory neuropeptides, such as calcitonin gene-related peptide (CGRP).ObjectivesWe sought to investigate whether (i) a brief meningeal K+stimulus leads to CGRP-dependent enhancement of meningeal afferent responses, and (ii) CSD-induced meningeal afferent activation and sensitization involve CGRP receptor signaling.MethodsExtracellular single-unit recording were used to record the activity of meningeal afferents in anesthetized male rats. Stimulations included a brief meningeal application of K+or induction of CSD in the frontal cortex using pinprick. CSD was documented by recording changes in cerebral blood flow using laser Doppler flowmetery. CGRP receptor activity was inhibited with BIBN4096 (333μM, i.v.).ResultsMeningeal K+stimulation acutely activated 86% of the afferent tested and also promoted in ~65% of the afferents a 3-fold increase in ongoing activity which was delayed by 23.3±4.1 min and lasted for 22.2±5.6 min. K+stimulation did not promote mechanical sensitization. Pretreatment with BIBN4096 suppressed the K+- induced delayed afferent activation, reduced CSD-evoked cortical hyperemia, but had no effect on the enhanced activation or mechanical sensitization of meningeal afferents following CSD.ConclusionWhile CGRP-mediated activation of meningeal afferents evoked by cortical efflux of K+could promote headache, acute activation of CGRP receptors may not play a key role in mediating CSD-evoked headache.Previous presentation of the research, manuscript, or abstractParts of the manuscript have been presented previously only in an abstract form.
Suppression of non-homologous end joining does not rescue DNA repair defects in Fanconi anemia patient cells
Authors: Thongthip Supawat , Conti Brooke A. , Lach Francis P. , Smogorzewska Agata 
Published: June 2017

ABSTRACTSevere cellular sensitivity and aberrant chromosomal rearrangements in response to DNA interstrand crosslink (ICL) inducing agents are hallmarks of Fanconi anemia (FA) deficient cells. These phenotypes have previously been ascribed to inappropriate activity of non-homologous end joining (NHEJ) rather than a direct consequence of DNA ICL repair defects. Here we used chemical inhibitors, RNAi, and Clusterd Regularly Interspaced Short Palindromic Repeat (CRISPR)-Cas9 to inactivate various components of NHEJ in cells from FA patients. We show that suppression of DNA-PKcs, DNA Ligase IV and 53BP1 is not capable of rescuing ICL-induced proliferation defects and only 53BP1 knockout partially suppresses the chromosomal abnormalities of FA patient cells.
Ethical, moral, and theological insights into advances in male pediatric and adolescent fertility preservation
Authors: Ramstein J. J. , Halpern J. , Gadzinski A. J. , Brannigan R. E. , Smith J. F. 
Published: June 2017

SummaryThe successful treatment of boys with cancer has led to increasing attention to preserving their quality of life after completing cancer therapy. One of the top priorities for living a full life is keeping open the opportunity to have children. While sperm banking for males facing sterilizing cancer treatment can be effective, this approach requires subsequent use of reproductive procedures such as in vitro fertilization (IVF) or intrauterine insemination (IUI) to achieve a pregnancy. Advances in fertility preservation techniques may allow pre‐pubertal boys to conceive using advanced stem cell technologies and stem cell transplantation in the future. This review summarizes the ethical positions of leading medical societies and explores the religious and moral stances of major religious institutions regarding these options.
No Pharmacokinetic Interaction Between the Hepatitis C Virus Inhibitors Elbasvir/Grazoprevir and Famotidine or Pantoprazole
Authors: Feng H‐P , Vaddady P , Guo Z , Liu F , Panebianco D , Levine V , Caro L , Butterton JR , Iwamoto M , Yeh WW 
Published: June 2017

AbstractUse of agents to suppress gastric acid secretion is common among patients with hepatitis C virus (HCV) infection. The aims of this open‐label, three‐period, fixed‐sequence study were to evaluate the effect of famotidine and pantoprazole on the pharmacokinetics and safety of elbasvir/grazoprevir fixed‐dose combination (FDC) in 16 healthy subjects. Elbasvir and grazoprevir each exhibited similar pharmacokinetics following single‐dose administration of elbasvir/grazoprevir with or without famotidine or pantoprazole. Geometric mean ratios (GMRs) of grazoprevir AUC(0,∞), Cmax, and C24 (elbasvir/grazoprevir + famotidine or elbasvir/grazoprevir + pantoprazole vs. elbasvir/grazoprevir) ranged from 0.89–1.17. Similarly, GMRs of elbasvir AUC(0,∞), Cmax, and C24 (elbasvir/grazoprevir + famotidine or elbasvir/grazoprevir + pantoprazole vs. elbasvir/grazoprevir) ranged from 1.02–1.11. These results indicate that gastric acid‐reducing agents do not modify the pharmacokinetics of elbasvir or grazoprevir in a clinically relevant manner and may be coadministered with elbasvir/grazoprevir in HCV‐infected patients without restriction.
Evaluation of a novel antimicrobial (lauric arginate ester) substance against biofilm of Escherichia coli O157:H7, Listeria monocytogenes, and Salmonella spp.
Authors: Sadekuzzaman Mohammad , Yang Sungdae , Kim Hyung‐Suk , Mizan Md. Furkanur Rahaman , Ha Sang‐Do 
Published: June 2017

SummaryThe purpose of this study was to evaluate the activity of a novel antimicrobial substance lauric arginate ester (LAE) against selected foodborne pathogens (Escherichia coli O157:H7, Listeria monocytogenes and Salmonella spp.) in biofilm. Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) were determined and showed that LAE exhibits a strong antimicrobial activity. Biofilms were grown on abiotic stainless steel, rubber, MBEC biofilm device) and biotic (lettuce) surfaces. The efficacy of LAE (50, 100 and 200 ppm) at reducing the biofilm cells on these surfaces was examined by applying LAE for 2 h. Results revealed that LAE exhibited the reduction in biofilm bacteria up to 7 log CFU cm−2, 3.5 log CFU cm−2, 4.0 log CFU peg−1 and 1.5 log CFU cm−2 on stainless steel, rubber, MBEC and lettuce surfaces, respectively. Overall, these results suggest that LAE has been shown to be a potential alternative to control bacteria in biofilm mode in food industry.
Effect of salt content on gelation of normal and wooden breast myopathy chicken pectoralis major meat batters
Authors: Xing Tong , Zhao Xue , Cai Linlin , Guanghong Zhou , Xu Xinglian 
Published: June 2017

SummaryThis study investigated the effects of salt content (0–4%) on water holding capacity (WHC), textural characteristics, rheological properties, and microstructure of cooked normal (NOR) and wooden breast (WB) chicken meat batters. Results indicated with 0–2% salt addition, the WB batters had significantly lower WHC and storage modulus (G’) compared with the NORs (P < 0.05). However, these differences were eliminated when salt contents were increased to 3% or 4%. In addition, the NORs formed more regular and pored networks than the WBs (0–2%). Salt level significantly affected the textural properties of both batter types (P < 0.05). The hardness of the WB batters was lower than NORs at all NaCl levels (P < 0.05). Overall, compared with NORs, the WB batters showed inferior gelation properties at salt contents of 0–2%, while increasing salt content to 3–4% can improve the WHC and microstructure of gels.
Enrichment of fresh pasta with antioxidant extracts obtained from artichoke canning by‐products by ultrasound‐assisted technology and quality characterisation of the end product
Authors: Pasqualone Antonella , Punzi Rossana , Trani Antonio , Summo Carmine , Paradiso Vito Michele , Caponio Francesco , Gambacorta Giuseppe 
Published: June 2017

SummaryThis work is aimed at: (i) analysing the extracts obtained from canning by‐products of three artichoke cultivars (Opal, Capriccio and Catanese) for antioxidant parameters; (ii) comparing UHPLC‐ESI‐MS/MS profile, colour, textural properties and cooking performance of fresh pasta enriched of the most antioxidant extract, with control pasta. The concentrated Catanese cv. extracts showed the highest antioxidant activity (1662 μmol Trolox equivalents L−1) and the highest levels of luteolin‐7‐O‐rutinoside, luteolin‐7‐O‐glucoside and apigenin‐7‐O‐rutinoside compared to other cultivars. Fresh pasta enriched of Catanese extract showed higher (P < 0.05) phenolic compounds and antioxidant activity (500 mg gallic acid kg−1 and 1324 μmol Trolox kg−1, respectively) than control pasta (306 mg gallic acid kg−1 and 886 μmol Trolox kg−1, respectively). The extract increased (P < 0.05) pasta brownness (from 19.93 to 23.34), and decreased yellowness (from 27.11 to 23.09), but did not alter textural and cooking parameters. So, pasta was a good vehicle to increase the antioxidant dietary intake.
Effects of thermosonication and orange by‐products extracts on quality attributes of carrot (Daucus carota) juice during storage
Authors: Adiamo Oladipupo Q. , Ghafoor Kashif , Al‐Juhaimi Fahad , Mohamed Ahmed Isam A. , Babiker Elfadil E. 
Published: June 2017

SummaryEffect of thermosonication on carrot juice containing peel (CJPL) and pulp (CJPP) extracts from orange at different concentration (0.5, 2.0 and 4.0 mg GAE per g extracts) of total phenolic contents (TPC) was evaluated for quality attributes. Thermosonication of juice was done at 52 °C, 6 min for CJPL and 60 °C, 5 min for CJPP (values based on our preliminary optimisation results of ultrasound process conditions of the juice) at 40 kHz and 110W. Effect of thermosonication and addition of peel and pulp extracts at highest concentration increased the TPC and antioxidant activity of the juice (P < 0.05). Highest inactivation of microorganisms and better sensory attributes was achieved in thermosonicated CJPP for 21 days. Titratable acidity, pH, browning index and viscosity were improved by thermosonication and at highest extract concentration. °Brix and total carotenoid were not significantly affected by treatments. Therefore, thermosonication at 60 °C and 4.0 mg GAE per g extract concentration of peel and pulp may be used in formulation of functional carrot juice with improved health properties.
Effect of defatted almond flour on cooking, chemical and sensorial properties of gluten‐free fresh pasta
Authors: Martínez Marcela Lilian , Marín María Andrea , Gili Renato Daniel , Penci María Cecilia , Ribotta Pablo Daniel 
Published: June 2017

SummaryThe aim of this work was to analyse the influence of defatted almond flour on soya bean‐based gluten‐free pasta. Optimal cooking time of pasta varied between 2.0 and 3.5 min, while cooking loss ranged 6.1% and 19.7%. The total protein content of samples varied from 30.4% to 41.0% (dry basis, db) in cooked pasta. The total phenols content of cooked samples varied between 1.66 and 2.99 mg ellagic acid equivalent/g, while the antioxidant activity (DPPH•) ranged between 19.1% and 41.9%. The sensory test showed no significant differences between the formulated pasta samples among brightness (3.20–3.27), surface appearance (1.14–1.20), hardness (2.14–2.36) and elasticity (1.56–1.71). Pasta developed is an innovative product that improves nutritional and functional properties of gluten‐free pasta compared to gluten‐free and traditional wheat flour pasta available on market.
Influences of pretreatment and drying methods on composition, micro/molecular structures and some health‐related functional characteristics of dietary fibre powder from orange pulp residues
Authors: Sungsinchai Sirada , Niamnuy Chalida , Jaree Attasak , Devahastin Sakamon 
Published: June 2017

SummaryInfluences of pretreatment methods (washing, blanching, soaking in ethanol), drying methods (hot air‐drying, infrared‐drying, microwave‐drying) and drying temperature on selected characteristics of dietary fibre powder from orange pulp residues were investigated. Pretreatments improved the hydration properties, oil‐holding capacity and glucose dialysis retardation index, but led to losses of fibres, decreased α‐amylase inhibitory activity and aflatoxin B1 adsorption capacity. Hydration properties, oil‐holding capacity and glucose uptake depended on the structure and porosity of the fibre, while the ability to inhibit α‐amylase and AFB1 adsorption depended more on the content and molecular fingerprinting of the fibre. Drying condition did not significantly affect functional properties of the fibre, except for the ability to uptake glucose, inhibit α‐amylase and adsorb AFB1 (P ≤ 0.05). Hot air‐drying at 60 °C resulted in fibre with the highest ability to decrease the rate of glucose and AFB1 adsorption.
Preparation and characterisation of isoflavone aglycone‐rich calcium‐binding soy protein hydrolysates
Authors: Wang Meng‐Ping , Lu Wei , Yang Juan , Wang Jin‐Mei , Yang Xiao‐quan 
Published: June 2017

SummaryIsoflavone aglycone‐rich calcium‐binding soy protein hydrolysates were prepared by subcritical water treatment and subsequent protease hydrolysis. Contaminated β‐glucosidase in the Protease M preparation could effectively convert glycosides into aglycones. Compared with Alcalase hydrolysates, Protease M hydrolysates exhibited higher molecular weight (>5000 Da) and more hydrophobic characteristics because of its weaker proteolytic activity. The antioxidant activity of Protease M hydrolysates was obviously improved. Initial increased DPPH and ABTS radical scavenging rate of Protease M hydrolysates may be ascribed to the conversion of isoflavones (<30 min) and a gradual release of antioxidant peptides. In the later hydrolysis, a gradual exposure of isoflavones involved in the interior of heat‐induced protein aggregates was mainly responsible for further improved antioxidant activities. Higher calcium‐binding capacity (up to 7.86%) with lower yield of peptide–calcium complex was observed for Protease M hydrolysates. These results could help researchers to develop a feasible protocol for producing nutrient‐enhanced soy protein hydrolysates.
Physical, nutritional and antioxidant properties of Zimbabwean bambara groundnut and effects of processing methods on their chemical properties
Authors: Oyeyinka Adewumi Toyin , Pillay Kirthee , Tesfay Samson , Siwela Muthulisi 
Published: June 2017

AbstractThis study examined the physical, nutritional and antioxidant properties of popular Zimbabwean bambara groundnut landraces and the effects of different processing methods on their chemical properties. The physical, nutritional and antioxidant properties of grains of the bambara landraces differed significantly with grain type, and the processing methods investigated had varying effects on the chemical properties of the grains. Bambara had significantly lower protein content than the reference common bean. Protein and carbohydrate content of the grains increased upon dehulling, while tannin (approx. 36%), total phenolic content (approx. 83%) and antioxidant activities (approx. 18%) decreased. Roasting alone seemed to have little or no effect on the nutrient content of the grains, while sifting significantly reduced the phenolic content and antioxidant activity of all the dehulled and roasted samples. The results indicate that roasting bambara grains would be a suitable method as it is relatively more conservative of nutrients and antioxidants than the other methods investigated.