bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current Evidence Supporting the Link Between Dietary Fatty Acids and Cardiovascular Disease
Authors: Hammad Shatha , Pu Shuaihua , Jones Peter J. 
Published: December 2015

AbstractLack of consensus exists pertaining to the scientific evidence regarding effects of various dietary fatty acids on cardiovascular disease (CVD) risk. The objective of this article is to review current evidence concerning cardiovascular health effects of the main dietary fatty acid types; namely, trans (TFA), saturated (SFA), polyunsaturated (PUFA; n‐3 PUFA and n‐6 PUFA), and monounsaturated fatty acids (MUFA). Accumulating evidence shows negative health impacts of TFA and SFA; both may increase CVD risk. Policies have been proposed to reduce TFA and SFA consumption to less than 1 and 7 % of energy intake, respectively. Cardiovascular health might be promoted by replacing SFA and TFA with n‐6 PUFA, n‐3 PUFA, or MUFA; however, the optimal amount of PUFA or MUFA that can be used to replace SFA and TFA has not been defined yet. Evidence suggests of the potential importance of restricting n‐6 PUFA up to 10 % of energy and obtaining an n‐6/n‐3 ratio as close as possible to unity, along with a particular emphasis on consuming adequate amounts of essential fatty acids. The latest evidence shows cardioprotective effects of MUFA‐rich diets, especially when MUFA are supplemented with essential fatty acids; namely, docosahexaenoic acid. MUFA has been newly suggested to be involved in regulating fat oxidation, energy metabolism, appetite sensations, weight maintenance, and cholesterol metabolism. These favorable effects might implicate MUFA as the preferable choice to substitute for other fatty acids, especially given the declaration of its safety for up to 20 % of total energy.
In Vitro Acetylcholinesterase‐Inhibitory Properties of Enzymatic Hemp Seed Protein Hydrolysates
Authors: Malomo Sunday A. , Aluko Rotimi E. 
Published: December 2015

AbstractThe aim of this work was to characterize the structural and functional properties of hemp seed protein‐derived acetylcholinesterase (AChE)‐inhibitory enzymatic hydrolysates. Hemp seed protein isolate hydrolysis was performed using six different proteases (pepsin, papain, thermoase, flavourzyme, alcalase and pepsin + pancreatin) at different concentrations (1–4 %). The degree of hydrolysis was directly related to the amount of protease used but had no relationship with AChE‐inhibitory activity. Amino acid composition results showed that the hemp seed protein hydrolysates (HPHs) had high levels of negatively charged amino acids (39.62–40.18 %) as well as arginine. The 1 % pepsin HPH was the most active AChE inhibitor with ~6 µg/mL IC50 value when compared to 8–11.6 µg/mL for the other HPHs. Mass spectrometry analysis showed that most of the peptides in all the hydrolysates were less than 1000 Da in size. However, the pepsin HPHs contained larger‐sized peptides (244–1009 Da) than the papain HPHs (246–758 Da), which in turn was larger than the alcalase HPH (246–607 Da). The higher AChE‐inhibitory effects of the pepsin HPHs may be due to increased synergistic effects from a wider peptide size range when compared to the papain and alcalase HPHs that had narrower ranges. The narrow peptide size range in the alcalase HPH confirms the higher efficiency of this protease in releasing small‐sized peptides from food proteins.
Quantification of Nonanal and Oleic Acid Formed During the Ozonolysis of Vegetable Oil Free Fatty Acids or Fatty Acid Methyl Esters
Authors: Tavassoli‐Kafrani M. H. , Foley P. , Kharraz E. , Curtis J. M. 
Published: December 2015

AbstractThe ozonolysis of unsaturated lipids is a process that has been used to generate aldehydes, acids, alcohols, and other biobased chemical intermediates. Reported here is a method that can be used to measure the formation of nonanal and oleic acid during the ozonolysis of unsaturated vegetable oil fatty acids or their methyl esters to indicate the extent of the ozonolysis reaction. Derivatization was performed using boron trifluoride in methanol solution to transform nonanal and oleic acid into nonanal dimethyl acetal and oleic acid methyl ester, respectively. Undecanal and 10‐heptadecenoic acid were used as internal standards and separation was performed using gas chromatography coupled with a flame ionization detector. The method was validated by performing a standard addition procedure in which nonanal or oleic acid standards were spiked into samples collected during the ozonolysis of oleic acid or canola oil fatty acid methyl ester (FAME). Linear regression results indicated that the measured nonanal and oleic acid are in good agreement with the actual amounts of nonanal and oleic acid added to the sample with at least 98 % recovery. The application of the method was demonstrated by the successful measurement of nonanal and oleic acid formed throughout the ozonolysis process for high oleic canola oil FAME.
Studying the influence of Bulletin Board System technologies on the communication culture of pre-internet Turkish-speaking online communities: a socio-technical approach
Authors: Furman Ivo 
Published: December 2015

AbstractHow does the technological infrastructure of a communications medium influence the culture of an online community? Taking up a socio-technical (STS) approach to online communities and computer mediated communication, this study introduces and explores the communication culture of Bulletin Board Systems (BBS) active in Turkey between 1995 and 1996. In the first part of the study, the researcher provides a brief history of BBS networks worldwide and of pre-Internet communication networks in Turkey. In the second part, using a sample from a privately owned archive of correspondences from Hitnet, a national-scale FidoNet-style BBS network popular in Turkey between 1992 and 1996, the study documents how some of the technical constraints on the level of hardware, software, and human-computer interaction (HCI) influenced the communication culture of the Hitnet community. At the same time, the study pays especial attention to the workarounds devised by community members to work around these constraints.
The Free Republican Party in the political cartoons of the 1930s
Authors: Başaran İnce Gökçen 
Published: December 2015

AbstractThe Free Republican Party (FRP; Serbest Cumhuriyet Fırkası), founded and dissolved in 1930, represented the second attempt to transition to a multi-party system in Turkey, following the formation of the Progressive Republican Party (Terakkiperver Cumhuriyet Fırkası) in 1924. In contrast to the oppositional establishment of the latter, the FRP seemed to be a state-originated project whose establishment was decided upon by the elites of the day, led by Mustafa Kemal Atatürk. Its representation in contemporary cartoons is deemed important today given the political cartoon’s ability to simplify complex political messages into understandable symbols and metaphors and to address or reach those who may not be literate. Taking into account the social structure of society during this period, this aspect of the reach of cartoons becomes particularly important. Political cartoons’ ability to both support the text in a newspaper and penetrate historical memory through stereotypes is also significant in terms of the representation of personalities and events. This article will attempt to analyze the formation of the FRP and the depiction of its elites through newspaper cartoons. Three prominent and pro-Republican People’s Party (Cumhuriyet Halk Partisi) newspapers of this period—namely Cumhuriyet, Milliyet, and Vakit—will provide the material for the content and thematic analysis of the study.
Gender and memory in the films of Tomris Giritlioğlu and Yeşim Ustaoğlu
Authors: Başcı Pelin 
Published: December 2015

AbstractThis article offers a critical reading, from the perspective of gender studies, of films produced in the politically charged environment of the 1990s and 2000s by directors Tomris Giritlioğlu and Yeşim Ustaoğlu. Giritlioğlu’s Ms. Salkım’s Diamonds (Salkım Hanımın Taneleri, 1999) and Autumn Pain (Güz Sancısı, 2008) were based on Yılmaz Karakoyunlu’s novels Salkım Hanım’ın Taneleri (1990) and Güz Sancısı (1992), while Ustaoğlu’s Waiting for the Clouds (Bulutları Beklerken, 2004) was inspired by Yorgo Andreadis’ biography, Tamama (1993). The films claim artistic license in presenting individual stories, yet they embellish their representation through documentary footage about silenced historical traumas, depicting female subjects as the store of traumatic national memories, such as the exodus of Pontic Greeks in 1916, the anti-minority Wealth Tax of 1942, and the anti-Greek pogroms of 1955. Underscoring Julia Kristeva’s notion of the “feminine” as a crucial aspect of these films, this article traces two strategies used by the directors: (1) recording personal stories in order to complicate nationalist narratives and their appeal to essentialized identities, and (2) gendering trauma as female suffering inflicted by patriarchal authority. The article concludes that, regardless of their public positions to the contrary, the directors engage in feminist politics by questioning the relationship between women and the nation, by broaching issues of social justice, and by highlighting the hybridity of identities and plurality of cultures.
Intergenerational Mobility and Equality of Opportunity
Authors: Torche Florencia 
Published: December 2015

AbstractIntergenerational mobility—the association between parents’ and adult children’s economic wellbeing—is an important sociological concept because it provides information about inequality of opportunity in society, and it has gained relevance in the recent past due to the increase economic inequality in most of the affluent world. This article provides an overview of the different measures of mobility used by sociologists and economists, as well as main empirical findings about mobility. I then move to topics that push mobility analysis beyond its bivariate focus: The association between intergenerational mobility and economic inequality, the mechanisms for mobility, and the validity of mobility as a measure of inequality of opportunity. I suggest that the association between mobility and inequality is likely spurious, driven by varying institutional arrangements across countries, and that mobility analysis is most useful when focused on describing the bivariate intergenerational association across countries and over time.
Modeling, Statistics and Political Circumstances
Authors: Lepenies Philipp 
Published: December 2015

AbstractThe notion of “economic development” dominates aid policy. A nation’s per capita Gross Domestic Product (gdp) determines whether that country is considered developed or less developed, and the standard measure of any developmental progress isgdpgrowth. This article investigates the evolution of the concept of economic development, as it emerged from a specific combination of modeling, statistics and political circumstances. In this story, Arthur Lewis played a decisive role, but only by building upon Colin Clark’s first global national income statistics, an indispensible foundation for Lewis’s seminal model of economic development. This model was embraced by policy makers longing for a theoretical framework to clarify and operationalize the hitherto vague concept of development. More importantly, however, the statistical indicator on which Lewis based his theory had already been universally accepted. In other words: statistics came before theory. This holds important lessons for alternative development ideas. It explains why the idea of economic development remains so firmly entrenched and suggests the conditions that might be necessary for an alternative theory to take hold.
Hausdorff Dimension of Sets of Escaping Points and Escaping Parameters for Elliptic Functions
Authors: Gałązka Piotr , Kotus Janina 
Published: December 2015

AbstractLetbe a non-constant elliptic function. We prove that the Hausdorff dimension of the escaping set offequals 2q/(q+1), whereqis the maximal multiplicity of poles off. We also consider theescaping parametersin the familyfβ=βf, i.e. the parametersβfor which the orbit of one critical value offβescapes to infinity. Under additional assumptions onfwe prove that the Hausdorff dimension of the set of escaping parametersεin the familyfβis greater than or equal to the Hausdorff dimension of the escaping set in the dynamical space. This demonstrates an analogy between the dynamical plane and the parameter plane in the class of transcendental meromorphic functions.
COST-EFFECTIVENESS OF RADIOFREQUENCY ABLATION VERSUS LASER FOR VARICOSE VEINS
Authors: Shepherd Amanda C. , Ortega-Ortega Marta , Gohel Manj S. , Epstein David , Brown Louise C. , Davies Alun H. 
Published: December 2015

Objectives: Although the clinical benefits of endovenous thermal ablation are widely recognized, few studies have evaluated the health economic implications of different treatments. This study compares 6-month clinical outcomes and cost-effectiveness of endovenous laser ablation (EVLA) compared with radiofrequency ablation (RFA) in the setting of a randomized clinical trial.Methods: Patients with symptomatic primary varicose veins were randomized to EVLA or RFA and followed up for 6 months to evaluate clinical improvements, health related quality of life (HRQOL) and cost-effectiveness.Results: A total of 131 patients were randomized, of which 110 attended 6-month follow-up (EVLA n = 54; RFA n = 56). Improvements in quality of life (AVVQ and SF-12v2) and Venous Clinical Severity Scores (VCSS) achieved at 6 weeks were maintained at 6 months, with no significant difference detected between treatment groups. There were no differences in treatment failure rates. There were small differences in favor of EVLA in terms of costs and 6-month HRQOL but these were not statistically significant. However, RFA is associated with less pain at up to 10 days.Conclusions: EVLA and RFA result in comparable and significant gains in quality of life and clinical improvements at 6 months, compared with baseline values. EVLA is more likely to be cost-effective than RFA but absolute differences in costs and HRQOL are small.
DEFINING ELIGIBILITY CRITERIA FOR FUNDING POLICIES AROUND IN VITRO FERTILIZATION
Authors: Menon Devidas , Nardelli Alexa A. , Motan Tarek , Klein Kristin , Stafinski Tania 
Published: December 2015

Objectives: This review aims to assess the state of the science around the potential impact of certain patient characteristics on the safety and effectiveness of in vitro fertilization (IVF).Methods: Following Cochrane Collaboration guidelines and the PRISMA statement, a comprehensive systematic review of reviews and recent primary studies examining the impact of paternal age and maternal age, smoking, and body mass index (BMI) on the safety and effectiveness of IVF was performed. Papers, published between January 2007 and June 2014, were independently reviewed and critically appraised by two researchers using published quality assessment tools for reviews and primary studies. Due to heterogeneity across papers (different study designs and patient selection criteria), a qualitative analysis of extracted information was performed.Results: Seventeen papers (ten systematic reviews and seven primary studies) were included. They comprised evidence from retrospective observational studies in which maternal age, BMI, and smoking status were explored as part of secondary analyses of larger studies. The majority of papers found that the likelihood of achieving a pregnancy was lower among women who were >40 years, had a BMI ≥ 25 and smoked. Advanced maternal age and BMI were also associated with higher rates of preterm birth and low birth weight.Conclusions: Based on available evidence, it may be appropriate to consider “maternal age” and “morbid obesity” in public funding policies that aim to maximize the effectiveness of IVF. However, given inconsistencies in the effect of smoking across different pregnancy-related outcomes, support for incorporating it into funding conditions appears weak.
Infective endocarditis prophylaxis: current practice trend among paediatric cardiologists: are we following the 2007 guidelines?
Authors: Naik Ronak J. , Patel Neil R. , Wang Ming , Shah Nishant C. 
Published: December 2015

AbstractBackgroundIn 2007, the American Heart Association modified the infective endocarditis prophylaxis guidelines by limiting the use of antibiotics in patients with cardiac conditions associated with the highest risk of adverse outcomes after infective endocarditis. Our objective was to evaluate current practice for infective endocarditis prophylaxis among paediatric cardiologists.MethodsA web-based survey focussing on current practice, describing the use of antibiotics for infective endocarditis prophylaxis in various congenital and acquired heart diseases, was distributed via e-mail to paediatric cardiologists. The survey was kept anonymous and was distributed twice.ResultsData from 253 participants were analysed. Most paediatric cardiologists discontinued infective endocarditis prophylaxis in patients with simple lesions such as small ventricular septal defect, patent ductus arteriosus, and bicuspid aortic valve without stenosis or regurgitation; however, significant disagreement persists in prescribing infective endocarditis prophylaxis in certain conditions such as rheumatic heart disease, Fontan palliation without fenestration, and the Ross procedure. Use of antibiotic prophylaxis in certain selected conditions for which infective endocarditis prophylaxis has been indicated as per the current guidelines varies from 44 to 83%. Only 44% follow the current guidelines exclusively, and 34% regularly discuss the importance of oral hygiene with their patients at risk for infective endocarditis.ConclusionSignificant heterogeneity still persists in recommending infective endocarditis prophylaxis for several cardiac lesions among paediatric cardiologists. More than half of the participants (56%) do not follow the current guidelines exclusively in their practice. Counselling for optimal oral health in patients at risk for infective endocarditis needs to be optimised in the current practice.
Impact of postoperative complications on hospital costs following the Norwood operation
Authors: McHugh Kimberly E. , Pasquali Sara K. , Hall Matthew A. , Scheurer Mark A. 
Published: December 2015

AbstractIntroductionPatients undergoing the Norwood operation consume considerable healthcare resources; however, detailed information regarding factors impacting hospitalisation costs is lacking. We evaluated the association of postoperative complications with hospital costs.MethodsIn the present study, we utilised a unique data set consisting of prospectively collected clinical data from the Pediatric Heart Network Single Ventricle Reconstruction trial linked at the patient level with cost data for 10 hospitals participating in the Children’s Hospital Association Case Mix database during the trial period. The relationship between complications and cost was modelled using linear regression, accounting for the skewed distribution of cost, adjusting for within-centre clustering and baseline patient characteristics.ResultsA total of 334 eligible Norwood records (97.5%) were matched between data sets. Overall, 82% suffered from at least one complication (median 2; with a range from 0 to 33). Those with complications had longer postoperative length of stay (25 versus 12 days, p<0.001), more total ventilator days (7 versus 5 days, p<0.001), and higher in-hospital mortality (17.6 versus 3.4%, p<0.006). Mean adjusted hospital cost in those with a complication was $190,689 (95% CI $111,344–$326,577) versus $120,584 (95% CI $69,246–$209,983) in those without complications (p=0.002). Costs increased with the number of complications (1–2 complications=$132,800 versus 3–4 complications=$182,353 versus ⩾5 complications=$309,372 [p<0.001]).ConclusionsThis merged data set of clinical trial and cost data demonstrated that postoperative complications are common following the Norwood operation and are associated with worse clinical outcomes and higher costs. Efforts to reduce complications in this population may lead to improved outcomes and cost savings.
Nurse Perspectives on the Practical, Emotional, and Professional Impacts of Living and Working in Post-earthquake Canterbury, New Zealand
Authors: Johal Sarbjit S. , Mounsey Zoe , Brannelly Petula , Johnston David M. 
Published: December 2015

AbstractIntroductionThis report explores nurses’ perspectives following the Canterbury (New Zealand) 2010-2011 earthquake sequence and the subsequent recovery process.ProblemLittle is known about the experiences of health care professionals during a disaster recovery process, and this research generates insights about the challenges faced.MethodsQualitative semi-structured interviews were undertaken with 11 nurses from the Christchurch (New Zealand) area to explore the challenges faced by the nurses during and following the earthquakes. The interviews took place three years after the start of the earthquake experience to enable exploration of longer term aspects of the recovery process. The interview transcripts were analyzed and coded using a grounded theory approach.ResultsThe data analysis identified that the nurses had faced a number of challenges and these were characterized as practical, emotional, and professional. While some of the challenges were short-lived in the aftermath of the earthquakes, some were long-lasting due to the extended nature of the recovery process. Dealing with house damage, insurance negotiations, and working in damaged environments had a negative impact on the nurses. The nurses experienced a range of emotions, both negative and positive, after the disaster, though many had needed time to elapse before feeling able to reflect on their experiences.DiscussionThe findings suggest that secondary stressors have a negative impact on the psychosocial recovery process. The nurses recognized that they received support from others and were also required to focus on others. Keeping busy appeared to be the most common coping strategy. This lack of reflection on their experiences may have resulted in delayed emotional responses. Some of the nurses changed their work role, hours, and responsibilities suggesting that working in this environment was having a detrimental impact.ConclusionThe research indicates the challenges faced by nurses in the initial impact of the earthquakes and during the longer term recovery process. There is a need to consider the psychosocial impact of working and living in a post-disaster context and to develop support packages to ensure the health and well-being of nurses in this environment.JohalSS,MounseyZ,BrannellyP,JohnstonDM.Nurse perspectives on the practical, emotional, and professional impacts of living and working in post-earthquake Canterbury, New Zealand.Prehosp Disaster Med.2016;31(1):10–16.