bluuebunny/crossref_metadata_2025_split huggingface dataset:
Full Abundance Study of Two Newly Discovered Barium Giants
Authors: Vitali Sara , Escorza Ana , Slumstrup Ditte , Jofré Paula 
Published: October 2024

Abstract
Barium (Ba) stars are chemically peculiar stars that show enhanced surface abundances of heavy elements produced by the slow-neutron-capture process, the so-called s-process. These stars are not sufficiently evolved to undergo the s-process in their interiors, so they are considered products of binary interactions. Ba stars form when a former Asymptotic Giant Branch (AGB) companion, which is now a white dwarf, pollutes them with s-process-rich material through mass transfer. This paper presents a detailed chemical characterization of two newly discovered Ba giants. Our main goal is to confirm their status as extrinsic s-process stars and explore potential binarity and white dwarf companions. We obtained high-resolution spectra with UVES on the Very Large Telescope to determine the chemical properties of the targets. We perform line-by-line analyses and measure 22 elements with an internal precision up to 0.04 dex. The binary nature of the targets is investigated through radial velocity variability and spectral energy distribution fitting. We found that both targets are enhanced in all the measured s-process elements, classifying our targets as Ba giants. This is the first time they are classified as such in the literature. Additionally, both stars present a mild enhancement in Eu, but less than in pure s-process elements, suggesting that the sources that polluted them were pure s-process sources. Finally, we confirmed that the two targets are RV variable and likely binary systems. The abundances in these two newly discovered polluted binaries align with classical Ba giants, providing observational constraints to better understand the s-process in AGB stars.
L’archive ouverte HAL-SHS : Comment ça marche, pourquoi s’en servir ?
Authors: Abela Caroline 
Published: October 2024

Tired of having your work locked in the ivory tower? Break out1. C’est ainsi que le mouvement du libre accès à l’information scientifique incite les chercheurs à sortir du modèle économique des publications payantes pour rendre leur production accessible au plus grand nombre. Cette incitation obéit à deux logiques qui s’entrecroisent : d’une part la documentation scientifique est coûteuse, d’autre part le libre accès à l’information scientifique est devenu un enjeu de société, un appel humaniste au partage de la connaissance considérée comme « bien commun ». Dans ce contexte, les archives ouvertes ont pour vocation de faciliter la communication des résultats de la recherche.
« Logement et représentations du logement pour les migrants et populations itinérantes »
Authors: Hoyez Anne-Cécile 
Published: October 2024

Ce séminaire, le troisième des quatre dans le cadre du programme franco-britannique « Migration, santé et bien-être », a eu pour objet l’accès au logement et ses impacts en matière de santé et de bien-être, en France et en Grande-Bretagne, pour les populations migrantes et itinérantes1. Les conditions matérielles de logement sont en effet souvent citées comme l’un des déterminants de la santé et du bien-être.
Effect of sacubitril and valsartan combined with conventional therapy on patients with heart failure
Authors: Wu Zhenyu , Cui Wen , Li Guoliang , Li Ling , Bian Yi 
Published: October 2024

Purpose: To investigate the clinical effectiveness of the combination of sacubitril and valsartan with conventional therapy in the treatment of patients with heart failure.
Methods: This was a retrospective study comprising 100 heart failure patients randomized into study (n = 57) and control groups (n = 43). The study group received sacubitril/valsartan along with conventional drug therapy while control group received only conventional drugs, viz, irbesartan, metoprolol slow release, and furosemide tablets. Echocardiogram showing left ventricular end-systolic diameter (LVESD), left ventricular end-diastolic diameter (LVEDD), left anterior descending artery (LAD), Nterminal pro-b-type natriuretic peptide (NT-proBNP), C-reactive protein (CRP), glomerular filtration rate (eGFR), and homocysteine (HCY) of the two groups were compared before and after treatment. Multiple regression was used to analyze the correlation between re-hospitalization and sacubitril/valsartan intervention.
Results: The study group showed significantly lower LVEF, LVESD, LVEDD, LAD, NT-proBNP, and homocysteine levels after treatment compared to control group (p < 0.05). Re-hospitalization for abnormal cardiovascular events between the two groups was significantly different in the adjusted Cox proportional hazards regression model. Furthermore, multiple regression analysis showed that sacubitril/valsartan treatment was the independent variable (p < 0.001).
Conclusion: Sacubitril/valsartan improves heart function, with reduced incidence of adverse effects without affecting renal function. Further studies are required to validate these findings by expanding sample size, strictly controlling data quality and strengthening follow-up.
Effect of N-acetylcysteine in treatment of COPD with pulmonary interstitial fibrosis, inflammatory factors and VEGF levels
Authors: Yang Jie , Cai Yuanping , Lu Qiaofa , Zhang Bo 
Published: October 2024

Purpose: To investigate the efficacy of N-acetylcysteine as an adjuvant therapy in chronic obstructive pulmonary disease (COPD) with pulmonary interstitial fibrosis (PIF), and its effect on inflammatory factors and serum vascular endothelial growth factor (VEGF) levels.
Methods: A total of 94 patients with COPD-PIF from May 2020 to May 2022 in Wuhan Fourth Hospital, China were equally randomized into study and control groups. Control group was administered conventional treatment while the study group was given N-acetylcysteine in addition to conventional treatment. Therapeutic efficacy, forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), FEV1/FVC, blood gas, pulmonary fibrosis, and oxidative stress were evaluated. Changes in inflammatory factors, serum vascular endothelial growth factor (VEGF), and incidence of adverse drug reactions were compared.
Results: The study group showed significantly higher efficacy, FEV1, FVC, FEV1/FVC compared to control group (p < 0.05). Also, study group showed significantly higher partial pressure of oxygen (PaO2), blood oxygen saturation, superoxide dismutase (SOD), and glutathione (GSH) levels after treatment compared to control group (p < 0.05). Platelet-derived growth factor (PDGF), transforming growth factor (TGF-β), vascular cell adhesion molecule (VCAM), tumor necrosis factor (TNF), interleukin-6 (IL-6), and vascular endothelial growth factor (VEGF) levels after treatment were significantly lower in the study group than in the control group (p < 0.05).
Conclusion: N-acetylcysteine as an adjuvant therapy for COPD-IF is highly effective, improves lung function and oxidative stress, reduces airway inflammation, and VEGF, and attenuates the degree of hypoxia and pulmonary fibrosis with no serious adverse effects. A larger sample size, multicenter, randomized trials to validate these findings and evaluate the downstream regulatory mechanism of Nacetylcysteine in COPD-PIF.
Ling gui shen fu decoction ameliorates cardiac injury in ischemic heart disease rats by regulating ANP32A/HIF2α/HMGB1 signal route
Authors: Gong Juanfen , Chen Yuanyuan 
Published: October 2024

Purpose: To investigate the effect of ling gui shen fu decoction (LGSFD) on cardiac injury and cardiomyocyte apoptosis in rats with ischemic heart disease (IHD), and to elucidate the underlying molecular mechanism.
Methods: An IHD rat model was established by performing coronary artery occlusion surgery on the left anterior descending (LAD) of rats. The rats were assigned equally to 5 groups: sham-operated group (sham group), IHD group, IHD + perindopril group, IHD + low- dose LGSFD group (IHD + LGSFD-L group), and IHD + high-dose LGSFD group (IHD+LGSFD-H group). The LGSFD was given via gavage. A hypoxia-induced cardiomyocyte model was established by subjecting H9C2 cells to hypoxia. Then, LGSFD-containing serum or blank serum was used to treat the hypoxic rat cardiomyocytes (H9C2). The severity of cardiac injury and extent of apoptotic changes in cardiomyocytes was determined using hematoxylin-eosin (H&E) staining and TUNEL staining, while immunoblotting was used to measure the protein expressions of ANP32A, p-AKT, AKT, HIF-2α, p-mTOR, mTOR and HMGB1.
Results: The cardiac injury of rats in the LGSFD groups was significantly reversed, relative to the IHD group (p < 0.05). Moreover, LGSFD reduced the level of apoptosis in hypoxia- induced H9C2 cells and upregulated the concentrations of ANP32A, p-AKT, HIF-2α and p-mTOR. However, the expression levels of HMGB1 were decreased in the heart tissues of IHD rats and hypoxic H9C2 cells. Silencing of ANP32A with ANP32A siRNA (siANP32A) down- regulated ANP32A, p-AKT, HIF-2α and p-mTOR, but up-regulated apoptosis and expression levels of HMGB1 in hypoxic H9C2 cells.
Conclusion: LGSFD ameliorates cardiac injury in IHD rats by inhibiting cardiomyocyte apoptosis via the ANP32A/HIF-2α/HMGB1 axis. Further investigations are recommended into the specific mechanism of LGSFD effect using clinical samples, in order to facilitate its clinical development.
Efficacy of Sini SAN combined with Sijunzi decoction in tic disorder, and intestinal microbiota in children
Authors: Guo Jianbo , Han Yangfei , Hao Feng , Song Lina , Zhang Wei 
Published: October 2024

Purpose: To evaluate the efficacy of Sini SAN and Sijunzi decoction in tic disorder, and intestinal microbiota in children.
Methods: This study enrolled 100 children with tic disorder from April 2020 to January 2023 in First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China. The control group (n = 45) was administered tiapride hydrochloride 50 mg daily, (gradually increased to thrice daily over 1 - 3 months, then reduced to once daily for 1 month, with a total treatment duration of 6 months). On the other hand, the study group (n = 55) received tiapride hydrochloride in addition to traditional Chinese medicine (TCM), including Sini San and Sijunzi decoction with specific herbs (Radix pseudostellariae, white peony), for 6 months. Efficacy, TCM syndrome scores, Yale Global Tic Severity Scale (YGTSS) scores, amino acid neurotransmitter levels, and α-diversity of intestinal microbiota were assessed in both groups before treatment and at 4th and 8th weeks after commencement of treatment.
Results: There was no significant difference in baseline characteristics between the study and control groups, indicating comparability (p > 0.05). The study group had a significantly higher total effectiveness/efficacy (p < 0.05). It exhibited greater improvements in Traditional Chinese Medicine (TCM) syndrome scores and YGTSS scores in the 4th and 8th week of treatment compared to control group (p < 0.05). Additionally, the study group exhibited significant decrease in glutamate and aspartate levels and a significant increase (p < 0.05) in α-diversity of intestinal microbiota except for Simpson index (p > 0.05).
Conclusion: The combination of TCM and tiapride hydrochloride improves efficacy, modulates neurotransmitter levels, alleviates symptoms, and improves α-diversity of intestinal microbiota.
Protective effect of evodiamine on acetic acid-induced gastric ulcers in rats through regulation of ROS/ICAM1/Nrf2 signaling pathway
Authors: Trinh Pham Thi Nhat , Dung Le Tien , Ngoc Pham Hong , Trang Nguyen Thi Thuy , Khoa Nguyen Cuu , Anh Hoang Ngoc , Osipov Alexey V. , Cheremnykh Elena G. , Utkin Yuri N. 
Published: October 2024

Purpose: To investigate the anti-inflammatory and antiprotozoal effects as well as chemical profile of ethanol extracts of Hedyotis diffusa (Rubiaceae) (HDE) and Scutellaria barbata (Lamiaceae) (SBE).
Methods: Dried whole plants collected in Vietnam were extracted with ethanol (30 and 96 %) by maceration for 4 weeks. The resulting extracts obtained after evaporating the solvent were stored in a refrigerator at 4 oC. Mouse carrageenan-induced inflammation and mouse macrophage cell line RAW264.7 were used to assess the in vivo and in vitro anti-inflammatory activities, respectively, while ciliate, Tetrahymena pyriformis was used to determine antiprotozoal effects. Ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) was employed to analyze the chemical profiles of the extracts.
Results: All the extracts manifested anti-inflammatory effects in vitro and in vivo. The HDE exhibited significantly higher in vitro anti-inflammatory activity than SBE (p < 0.05). Furthermore, in vivo antiinflammatory activity was higher in SBE compared to HDE. Both extracts exhibited antiprotozoal effects. The 96 % ethanol extract of both plants were more active than the 30 % ethanol extracts. Analysis by UHPLC‐Q‐TOF- MS revealed the presence of chrysin, apigenin and apigenin derivatives, naringenin, wogonin, quercetin and quercetin derivatives, as well as scutellarin.
Conclusion: The HDE and SBE extracts from Vietnam exhibit significant in vivo and in vitro antiinflammatory activities and in addition, antiprotozoal activity against Tetrahymena pyriformis. These plants, therefore, are potential sources of antiprotozoal agents.
Non-State Actors in Asymmetric Conflicts: What does It Mean and What Follows of It
Authors: Deriglazova L. V. 
Published: October 2024

The article examines the problem of the participation of non-state actors in armed conflicts in the post-war period. The study is based on the theory of asymmetric conflict, which offers hypotheses about the reasons for the paradoxical defeat of developed countries against relatively weak opponents, including non-state actors. The empirical basis of the study is armed conflict databases, which allow us to test sole observations and hypotheses about the characteristics of asymmetric armed conflicts. The study uses the databases of the Uppsala Conflict Data Program Project (Sweden) and the COSIMO Project (University of Heidelberg, Germany) as well as publications of the Stockholm International Peace Research Institute (SIPRI). The study shows that the phenomenon of asymmetric conflicts reflects several important patterns of armed conflicts in the post-war period: the predominance of intrastate over interstate conflicts; the internationalisation of armed conflicts through the involvement of other countries, international organisations or non-state actors; the direct or indirect involvement of great powers in such conflicts; and the majority of armed conflicts occurring in Asia, Africa and the Middle East. Post-war armed conflicts are often referred to as “proxy wars” because the direct participants in the conflict are supported by external actors – states or non-state actors. The issues in conflicts between states and non-state actors are often political in nature, and the fundamental distinction between domestic and foreign policy has been overcome. The post-war period shows a gradual change of attitude towards the participation of non-state actors in armed conflicts, which reflects the recognition of their legitimacy as participants in the conflict, the negotiation and conclusion of agreements on the cessation of hostilities. Non-state actors in armed conflicts are themselves legitimised as representing the interests of particular groups and the goals of their struggle. UN peacekeeping operations since the end of the Cold War confirm these changes. Research on the participation of non-state actors in armed conflict reveals a broadening of the agenda and methodology for the study of post-war armed conflict, reflecting significant changes in the practice of international relations. These changes concern who is recognised as a legitimate actor in international relations, what role non-state actors play in armed conflict, and how non-state actors are viewed by other actors in international relations – states, international governmental and non-governmental organisations.
Potenciando el aprendizaje en lengua y literatura: técnicas activas para estudiantes de segundo año de educación general básica
Authors: Anchundia Vera Aura Elizabeth 
Published: October 2024

Las técnicas activas son estrategias didácticas que implican la participación activa del estudiante en su propio proceso de aprendizaje, fomentando el pensamiento crítico, la creatividad y el desarrollo de habilidades comunicativas. El objetivo principal de este estudio es diseñar una guía de actividades que fortalezca el uso de técnicas activas en la enseñanza de Lengua y Literatura para estudiantes de segundo año de Educación General Básica en la Unidad Educativa "Luis A Martínez". Este estudio se direcciona hacia una ruta mixta y emplea una metodología experimental con un grupo de pretest-postest y la aplicación de una encuesta estructurada para diagnosticar y caracterizar epistemológicamente las debilidades en comprensión lectora. Los resultados mostraron una mejora en los niveles de comprensión lectora, tanto literal, inferencial como crítico, lo que evidencia la eficacia en la implementación de técnicas activas por parte de los docentes. Estos hallazgos contribuyen a enriquecer las prácticas educativas y a fomentar un aprendizaje más participativo y significativo en el aula.
The Fire-ViT Model for Tunnel Fire Detection with Vision Transformer Improvement
Authors: Liu Xiaobing , Mariano Vladimir Y. 
Published: October 2024

Smoke detection in tunnels presents unique challenges, including low light conditions, visual obstructions like smoke and headlights, and the need to analyze ultrahigh-resolution images. To address these challenges, this study introduces an innovative model named Fire-ViT, leveraging the vision transformer (ViT) architecture. Unlike traditional convolutional neural networks that often struggle with false positives under these complex conditions, Fire-ViT incorporates an attention mechanism and multiperceptron layer, significantly enhancing its capability to discern details in high-resolution images specific to tunnel environments. The model’s performance is outstanding, achieving an accuracy rate of 99.87% on a high-resolution tunnel image dataset, markedly surpassing that of conventional models. Notably, Fire-ViT not only elevates detection accuracy and robustness but also cuts training time in half. This efficiency, coupled with its adaptability to the intricate tunnel environment, makes Fire-ViT an ideal solution for early warning systems against fires in tunnels, fulfilling the demand for high-standard, fine-grained fire detection.

Received: 15 June 2024 | Revised: 13 August 2024 | Accepted: 14 September 2024

Conflicts of Interest
The authors declare that they have no conflicts of interest in this work.

Data Availability Statement
The data that support the findings of this study are openly available in Kaggle at https://www.kaggle.com/datasets/xiaobingliu323/ tunnelfire2024/data.

Author Contribution Statement
Xiaobing Liu：Conceptualization, Methodology, Software, Formal analysis, Investigation, Data curation, Writing – original draft, Writing – review & editing, Visualization, Supervision, Project administration, Funding acquisition. Vladimir Y. Mariano: Methodology, Validation, Resources, Writing – review & editing, Supervision, Project administration.
La constitución gratuita del usufructo de inmuebles en un contexto familiar
Authors: Llopis Mengual Pablo 
Published: October 2024

El presente trabajo pretende analizar si, con el objetivo de evitar la progresividad del IRPF y, así, disminuir la carga impositiva familiar total, es económicamente aconsejable que el contribuyente que obtiene numerosas rentas constituya a favor de su hijo el usufructo temporal inter vivos a título gratuito sobre bienes inmuebles en arrendamiento. Para ello, desde el punto de vista tributario, debe tenerse en consideración la situación familiar a los efectos de valorar si es recomendable o no dicha operación. En particular, se debe valorar la posible pérdida del mínimo por descendientes, así como si el inmueble será objeto de transmisión en un futuro. Asimismo, además de comparar la constitución de este derecho real con la donación de la propiedad del inmueble, es necesario el estudio del impacto de las diferentes figuras impositivas, tanto en el ascendiente donante como en el descendiente donatario, en el momento de constitución del usufructo temporal y en la extinción del mismo, instante en el cual se consolida la plena propiedad y se vuelve a la situación inicial.
European Television Industries
Authors: Iosifidis Petros , Steemers Jeanette , Wheeler Mark 
Published: October 2024

The last few decades have witnessed profound changes in the structure, content, technology, regulation and cultural forms of European television industries. Television in Europe operates in an increasingly globalised communications market characterised by commercialisation, fragmentation and transnational ownership. Digital transmission has resulted in an abundance of televisual offerings, operating in a less heavily regulated dual system of competitive private and publicly owned television channels. While these changes offer vast opportunities to both organisations and consumer-citizens in terms of access and choice, they also bring about uncertainties about the future shape of the medium. How will television be funded and watched in the future? Will public broadcasting survive in the modern era? Will consumers respond to technological developments? How can regulation encourage investment, uphold quality and effectively address concentration of media ownership? What is Europe’s position within a global television marketplace?
European Television Industries addresses these issues in the context of developments in technology, changing ownership patterns, legislative change and the much heralded likelihood of convergence between telecommunications, broadcasting and computing. Concentrating on the historical, economic, cultural, technological, and political factors behind change, the book provides an opportunity to construct a conceptual and analytical base on which to judge future developments in television in Europe. Designed for academics, practitioners and students, this book critically evaluates models, frameworks, debates and observations relating to the future of the medium.