bluuebunny/crossref_metadata_2025_split huggingface dataset:
Secondary Prevention of Cervical Cancer: ASCO Resource-Stratified Clinical Practice Guideline
Authors: Jeronimo Jose , Castle Philip E. , Temin Sarah , Denny Lynette , Gupta Vandana , Kim Jane J. , Luciani Silvana , Murokora Daniel , Ngoma Twalib , Qiao Youlin , Quinn Michael , Sankaranarayanan Rengaswamy , Sasieni Peter , Schmeler Kathleen M. , Shastri Surendra S. 
Published: May 2017

(Abstracted from J Global Oncol 2017; DOI:10.1200/JGO.2016.006577)
The aim of the guideline was to provide global resource-stratified, evidence-based recommendations on the secondary prevention of cervical cancer, while accounting for wide variations in resource levels and health systems. These are the first cervical cancer screening guidelines that offer recommendations tailored to resource availability in the settings where women live.
Gynecological and Obstetrical Outcomes After Laparoscopic Repair of a Cesarean Scar Defect in a Series of 38 Women
Authors: Donnez Olivier , Donnez Jacques , Orellana Renan , Dolmans Marie-Madeleine 
Published: May 2017

(Abstracted from Fertil Steril 2017;107:289–296)
As the number of cesarean deliveries has continued to rise worldwide in recent decades, cesarean scar defects have been increasingly described.
Non-invasive Prenatal Testing and the Unveiling of an Impaired Translation Process
Authors: Murdoch Blake , Ravitsky Vardit , Ogbogu Ubaka , Ali-Khan Sarah , Bertier Gabrielle , Birko Stanislav , Bubela Tania , De Beer Jeremy , Dupras Charles , Ellis Meika , Granados Moreno Palmira , Joly Yann , Kamenova Kalina , Master Zubin , Marcon Alessandro , Paulden Mike , Rousseau François , Caulfield Timothy 
Published: May 2017

(Abstracted from J Obstet Gynaecol Can 2017;39(1):10–17)
Noninvasive prenatal testing (NIPT) using cell-free DNA (cfDNA) is an exciting new technology with many potential clinical benefits. However, the commercialization of these tests and the potential economic benefits to the laboratories that perform the testing have led to concern that the limitations are being downplayed and the benefits overstated.
SERI Surgical Scaffold in 2-Stage Breast Reconstruction: 2-Year Data from a Prospective, Multicenter Trial
Authors: Karp Nolan , Choi Mihye , Kulber David A. , Downey Susan , Duda Gloria , Kind Gabriel M. , Jewell Mark L. , Murphy Diane K. , Lehfeldt Max R. , Fine Neil 
Published: May 2017

Background:
Soft-tissue support devices are used during breast reconstruction. This study investigated long-term clinical data following SERI Surgical Scaffold (SERI) implantation, a bioresorbable, silk-derived scaffold for soft-tissue support.

Methods:
This was a prospective, multicenter study in 103 subjects who received SERI during stage 1 of 2-stage breast reconstruction with subpectoral tissue expander placement (Natrelle Style 133V; Allergan plc, Dublin, Ireland) followed by subpectoral breast implant placement. Investigator satisfaction (11-point scale: 0, very dissatisfied and 10, very satisfied) at 6 months was the primary endpoint. Ease of use, satisfaction, scaffold palpability/visibility, breast anatomy measurements via 3D images, SERI integration, histology, and safety were also assessed through 2 years after stage 1 surgery.

Results:
Analyses were performed on the per-protocol population (103 subjects; 161 breasts) with no protocol deviations that could affect outcomes. Ease of use and subject and investigator satisfaction with SERI were high throughout 2 years. Breast anatomy measurements with 3D images demonstrated long-term soft-tissue stability of the lower breast mound. Key complication rates per breast were tissue/skin necrosis and wrinkling/rippling (8.1% each) and seroma, wound dehiscence, and breast redness (5.0% each). Over 2 years, 4 breasts in 4 subjects underwent reoperation with explantation of any device; 2 breasts required SERI explantation. SERI was retained in 98.8% of breasts (159/161) at 2 years.

Conclusions:
SERI was associated with high and consistent levels of investigator and subject satisfaction and demonstrated soft-tissue stability in the lower breast through 2 years. SERI provides a safe, long-term benefit for soft-tissue support in 2-stage breast reconstruction.
AmpliVue Is a Practical and Timely Test for the Detection of HSV From Keratitis Specimens
Authors: Kowalski Regis P. , Karenchak Lisa M. , Dhaliwal Deepinder K. , Mammen Alex 
Published: May 2017

Objective:
The laboratory diagnostic detection of herpes simplex virus (HSV) from eye samples must be practical, timely, and definitive for appropriate therapy. Although polymerase chain reaction (PCR) and/or cell culture can be definitive, HSV results can be delayed. Enzyme Linked Virus Inducible System (ELVIS) is a test that can provide results within 24 to 48 hr. We evaluated “AmpliVue HSV 1+2 Assay” as a molecular colorimetric test that can detect HSV (1 or 2) DNA within 1 hr.

Methods:
Cornea/conjunctival samples were tested retrospectively with AmpliVue against 53 true-positive and 20 true-negative specimens collected in chlamydial transport medium. All clinical specimens were tested by cell culture isolation, PCR, and ELVIS for routine patient care.

Results:
The sensitivity of AmpliVue against ocular samples that were both culture-positive and PCR-positive was 84%. The specificity of AmpliVue was 100%. Only one clinical sample was HSV-2 positive, whereas all others tested positive for HSV-1. Based on PCR-positive and cell culture-negative samples, AmpliVue (11 of 17) tested more positive than ELVIS (0 of 17) (P=0.003, Fisher Exact).

Conclusions:
AmpliVue is moderately sensitive and highly specific as a practical and timely diagnostic test for detecting ocular HSV. Expertise is readily achieved and the test is straightforward with easy interpretation. Negative AmpliVue testing must be confirmed with PCR. AmpliVue has potential as an office-based diagnostic test.
Fungal Keratitis Associated With Airborne Organic Debris and Soft Contacts Lenses: Case Reports and Review of the Literature
Authors: Hodkin Michael J. , Gustus Ryan C. 
Published: May 2017

Objectives:
To report two cases of fungal keratitis in soft contact lens wearers who were exposed to environmental mold.

Methods:
Case reports, with review of the relevant literature.

Results:
Two otherwise healthy middle-aged women who were soft contact lens wearers developed fungal keratitis about 1 week after heavy exposure to environmental mold. Culture results showed Aspergillus from one patient and the unusual combination of Trichoderma and Penicillium from the other. Both were treated with topical natamycin, topical fluoroquinolone antibiotic prophylaxis, and periodic ulcer debridement. After many weeks of treatment, both ulcers healed with subsequent scarring. Because the ulcers were located in the peripheral cornea in both cases, excellent final visual acuities were achieved. Fungal keratitis cases like these are rarely seen at our referral clinic, which is located in the temperate climate of northeastern Indiana.

Conclusions:
In addition to the usual recommended contact lens care guidelines, it may be prudent for eye care providers to warn patients against wearing their contact lenses in situations likely to result in heavy exposure to organic matter or, at the very least, to wear tight-fitting goggles for eye protection.
Predictors of bile tree pathology in patients presenting with gallbladder disease
Authors: Rahal Mahmoud A. , Rammal Mohammad O. , Karaoui Walid , Hallal Ali , Tamim Hani , Shaib Yasser 
Published: May 2017

Background
Patients with gallstone disease can present with elevated liver function tests (LFTs). It is often challenging to differentiate those with a common bile duct (CBD) stone from those without a CBD stone on the basis of the LFTs levels. In this study, we aim to evaluate the predictors of a CBD stones among patients presenting with symptomatic gallbladder disease and elevated LFTs.

Patients and methods
We retrospectively examined all patients who had undergone a cholecystectomy between January 2010 and December 2015. Patients with symptomatic cholelithiasis and increased LFTs were included. Patient characteristics, imaging findings, lab findings, endoscopic interventions, and operative report were recorded and evaluated. The diagnosis of CBD stones was made on the basis of ERCP and IOC findings.

Results
We included 354 patients in the final analysis. Of these, 113 (32%) had confirmed choledocholithiasis. The prevalence of CBD stones among biliary colic, acute cholecystitis, and pancreatitis patients was 47, 25, and 26%, respectively. γ-Glutamyl transferase and direct bilirubin had the highest sensitivities for CBD stones among these patients (83 vs. 79%). In the setting of biliary colic, total bilirubin was highly predictive of CBD stones with a positive predictive value of 85%. In the setting of acute cholecystitis, elevated LFTs were even less significant in predicting stones, with a positive predictive value of less than 40% for most.

Conclusion
Although γ-glutamyl transferase and bilirubin levels showed a relatively higher sensitivity for CBDS compared with the other LFTs, these were not reliable enough because of high false-positive as well as false-negative values, especially in patients presenting with acute cholecystitis.
Mosquito-Borne Diseases as a Global Health Problem: Implications for Pregnancy and Travel
Authors: Diouf Khady , Nour Nawal M. 
Published: May 2017

Importance
Mosquitoes are the most common disease vectors worldwide. A combination of factors, including changes in public health policy, climate change, and global travel, has led to the resurgence and spread of these diseases in our modern world. Pregnant women are vulnerable to a number of these illnesses, and obstetricians are likely to encounter pregnant travelers who have been exposed.

Objective
This review was conducted to summarize knowledge of mosquito-borne diseases and their relevance in pregnancy. This will allow obstetricians to provide proper advice regarding travel and prepare providers to recognize manifestations of these illnesses in the pregnant woman.

Evidence Acquisition
A review of the current literature was performed to summarize the various manifestations of mosquito-borne illnesses in pregnant women and discuss obstetric outcomes and management of disease in pregnancy.

Results
Mosquito-borne illnesses usually manifest after a period of incubation lasting from days to weeks. Symptoms usually include a febrile illness but may be nonspecific and may masquerade as pregnancy-specific illnesses such as preeclampsia or HELLP (hemolysis, elevated liver enzyme levels, and low platelet levels); a large number of patients remain asymptomatic. Pregnancy-related outcomes include spontaneous abortion, intrauterine fetal demise, intrauterine transmission to the fetus, and congenital anomalies. Management during pregnancy is mainly supportive. Precautions against disease include protective clothing and insect repellents. Vaccines are either available or in development.

Conclusions and Relevance
Mosquito-borne disease should be considered in pregnant women who present with a febrile illness and a relevant exposure history. Prompt recognition can allow supportive treatment to the mother and fetal resuscitation and surveillance.

Target Audience
Obstetricians and gynecologists, family physicians.

Learning Objectives
After completing this activity, the learner should be better able to describe the presentation, symptoms, and diagnosis of mosquito-borne diseases including malaria, chikungunya, dengue, yellow fever, West Nile virus, Zika, and filariasis; describe the risks of mosquito-borne diseases to the pregnant woman and her fetus; and outline the management considerations for pregnant women with specific mosquito-borne infections.
The Risks of Marijuana Use During Pregnancy
Authors: Volkow Nora D. , Compton Wilson M. , Wargo Eric M. 
Published: May 2017

(Abstracted from JAMA 2017;317(2):129–130)
This article highlights the risks associated with the use of marijuana during pregnancy. In the context of marijuana’s legalization in 29 states and Washington, DC, and the antinausea effects of tetrahydrocannabinol, the main psychoactive ingredient in it, there is an increased risk of pregnant women turning to marijuana to control nausea in the first trimester.
Imaging plus X: multimodal models of neurodegenerative disease
Authors: Oxtoby Neil P. , Alexander Daniel C. 
Published: May 2017

Purpose of review
This article argues that the time is approaching for data-driven disease modelling to take centre stage in the study and management of neurodegenerative disease. The snowstorm of data now available to the clinician defies qualitative evaluation; the heterogeneity of data types complicates integration through traditional statistical methods; and the large datasets becoming available remain far from the big-data sizes necessary for fully data-driven machine-learning approaches. The recent emergence of data-driven disease progression models provides a balance between imposed knowledge of disease features and patterns learned from data. The resulting models are both predictive of disease progression in individual patients and informative in terms of revealing underlying biological patterns.

Recent findings
Largely inspired by observational models, data-driven disease progression models have emerged in the last few years as a feasible means for understanding the development of neurodegenerative diseases. These models have revealed insights into frontotemporal dementia, Huntington's disease, multiple sclerosis, Parkinson's disease and other conditions. For example, event-based models have revealed finer graded understanding of progression patterns; self-modelling regression and differential equation models have provided data-driven biomarker trajectories; spatiotemporal models have shown that brain shape changes, for example of the hippocampus, can occur before detectable neurodegeneration; and network models have provided some support for prion-like mechanistic hypotheses of disease propagation. The most mature results are in sporadic Alzheimer's disease, in large part because of the availability of the Alzheimer's disease neuroimaging initiative dataset. Results generally support the prevailing amyloid-led hypothetical model of Alzheimer's disease, while revealing finer detail and insight into disease progression.

Summary
The emerging field of disease progression modelling provides a natural mechanism to integrate different kinds of information, for example from imaging, serum and cerebrospinal fluid markers and cognitive tests, to obtain new insights into progressive diseases. Such insights include fine-grained longitudinal patterns of neurodegeneration, from early stages, and the heterogeneity of these trajectories over the population. More pragmatically, such models enable finer precision in patient staging and stratification, prediction of progression rates and earlier and better identification of at-risk individuals. We argue that this will make disease progression modelling invaluable for recruitment and end-points in future clinical trials, potentially ameliorating the high failure rate in trials of, e.g., Alzheimer's disease therapies. We review the state of the art in these techniques and discuss the future steps required to translate the ideas to front-line application.
Method of analysis of asymmetrical thermal field in a double insulated wire
Authors: Golebiowski Jerzy , Zareba Marek 
Published: May 2017

Purpose
The purpose of this article is investigating the impact of the spatially variable heat transfer coefficient on the thermal field in the double insulated wire.

Design/methodology/approach
The effect of the air boundary layer was modelled by means of changing the total heat transfer coefficient on the external perimeter of the wire. This leads to an elliptical boundary problem with Hankel’s condition dependent on the angular coordinate. The eigenfunctions of the problem were determined analytically. On the other hand, the unknown coefficients of eigenfunctions and the constants were calculated numerically by solving a respective system of algebraic equations. The steady state current rating was determined with an iterative method.

Findings
By means of the presented method, the thermal field distribution deprived of axial symmetry in the double insulated wire was determined. The obtained results have good physical interpretation and were verified with the finite element method (by means of NISA v. 16 software). The determined values of the steady-state current rating were compared with those calculated by means of the equivalent heat transfer coefficient method and the International Electrotechnical Commission (IEC) standard.

Research limitations/implications
The method is applied to analyse scalar fields in layered cylindrical structures. This could be expanded to the case of a wire of any number of insulation layers. What is more, one could also consider heat sources without axial symmetry and located within the external area.

Originality/value
The analytical method of determining a thermal field deprived of axial symmetry in heterogeneous cylindrical system (the wire composed of three different materials) was developed.
Modelling identity types through agency: part 1 defragmenting identity theory
Authors: Yolles Maurice , Di Fatta Davide 
Published: May 2017

Purpose
There is fragmentation in the academic study of identity theory, and it is dislocated from personality theory. The paper aims to develop a model that resolves both of these issues using autonomous agency theory. It is shown that identities can be evaluated using mindset agency theory. Application is then made to a case study of Donald Trump’s US election campaign.

Design/methodology/approach
In the first of this three-part paper, the fragmented identity theory is examined ontologically to generate a coherent model of multiple identities.

Findings
A new coherent model of multiple identities is created.

Originality/value
There is not currently any that has created coherent theory of multiple identities.
How does entrepreneurial opportunity affect the decision-making process of effectuation?
Authors: Long Dan , Xia Zi-yao , Hu Wang-bin 
Published: May 2017

PurposeThe purpose of this paper is to bridge the obvious gap presented in research on antecedents of effectuation by building a research model from the perspectives of effectuation and entrepreneurial opportunity.Design/methodology/approachThis paper examines the effects of patterns of opportunity discovery and the innovativeness of entrepreneurial opportunity on the decision-making process of effectuation in new venture creation. Eight hypotheses are put forward and examined by hierarchical multiple logistic regression. The data in this paper are based on the first two rounds of survey data from Chinese Panel Study of Entrepreneurial dynamics.FindingsThe empirical results show that patterns of opportunity discovery have significant positive effects (at least partially) on effectuation. Namely, entrepreneurs employing fortuitous discovery tend to use available means and leverage contingency. And with lower innovativeness of opportunity, entrepreneurs are more likely to use affordable loss and leverage contingency.Research limitations/implicationsThe study is limited to each dimension of effectuation based on the single-item measure, which cannot completely reflect the effectual construct. More research should to be done to improve measures of effectuation.Practical implicationsThe findings are useful for entrepreneurs to make effective decisions whether to choose effectuation in the face of different patterns of opportunity discovery. Besides, it provides the advice on how to cope with the innovativeness of opportunity and seize entrepreneurial opportunities to entrepreneurs.Originality/valueThis paper first systematically studies the effects of entrepreneurial opportunity on effectuation, making up for the obvious gap of research on antecedents of effectuation.
Social question and answer sites: the story so far
Authors: Khusro Shah , Alam Aftab , Khalid Shah 
Published: May 2017

PurposeSocial question and answer (SQA) site is one of the factors that boosted up and popularized the vision of social web. It enables community members to post highly valued answers to globally asked questions and information seekers to grab intellectual information in a contextual, concise, and meaningful format at the cost of investing a few minutes. The purpose of this paper is to present a common architecture, history, and a comprehensive review of such sites.Design/methodology/approachA critical and analytical investigation of the state-of-the-art SQA sites and relevant literature has been carried out with the intention to explore the noticeable features of such sites.FindingsBy studying relevant literature, and analysing a number of existing systems, a number of research challenges are identified and a generic architecture of SQA sites is contributed.Practical implicationsThe review contributes a comprehensive knowledge about SQA systems and aims to be helpful to new researchers who want to get a broad picture of SQA systems on a single platform. The domain is in its infancy and requires tremendous efforts from the research community to explore its salient aspects with respect to the human world.Originality/valueThe study inspects SQA sites on a large scale and makes an original contribution by presenting a comprehensive review, future research challenges, and a generic architecture of SQA sites.
Effects of mood states and team identification on pricing in the secondary ticket market
Authors: Ballouli Khalid , Reese Jason , Brown Brandon 
Published: May 2017

Purpose
Although current literature offers support for understanding sport consumer behavior from psychological and sociological perspectives, there is a lack of research that examines the effect of one’s emotional response to team outcomes on subsequent economic decisions. The purpose of this paper is to bridge this gap by studying how emotional responses to sport events moderate a typical endowment bias in the secondary ticket market.

Design/methodology/approach
This research comprised a 3×2×2 between-participants design with emotional state (positive, negative, and neutral), role (seller, buyer), and fan identification (high, low) as the three factors. Prospect theory and social identity theory guided hypothesis development whereby it was proposed that, depending on the affective response of study participants to positive, negative, or neutral publicity concerning the team, team identification would impact the transaction function (buyers vs sellers) on price values for tickets to a future event.

Findings
Findings revealed an interaction effect of emotions and team identification on the endowment effect to the extent that bargaining gaps between sellers and buyers increased or decreased depending on mood states and levels of identification with the team.

Originality/value
This study adds to the literature on emotions and the key role they play in effecting pricing decisions and consumer behavior, especially given fan identification is such a significant area of study with numerous implications for sport business and management.
The influence of vegetable puree containing carotenoids on the nutrient composition and structure of milk yoghurt
Authors: Guz Elena Aleksandrovna , Novitskaya Elena Gennadievna , Kalenik Tatyana Kuzminichna , Levochkina Lyudmila Vladimirovna , Piekoszewski Wojciech 
Published: May 2017

The aim of this study was to develop technology to produce a mashed pumpkin yoghurt rich in β‐carotene and to check its physicochemical properties and nutritional values. The structural and mechanical properties of the yoghurt product, as well its basic nutrient content and antioxidant activity, were studied. Yoghurt fortified with pumpkin puree has the potential to normalise the commensal intestinal microbiota and has potential as a dietary health supplement. The experimental yoghurt samples that were produced had physicochemical properties comparable to commercially produced yoghurt: the pumpkin‐supplemented samples contained 4.5% fibre, 8.5 mg/100 g vitamin C and 8.9 mg/100 g β‐carotene.