bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pola Weiss, registrando cuerpos, movimientos y desbordes
Authors: Lucero Maria Elena 
Published: December 2017

<p>Pola Weiss (1947-1990) es considerada una artista emblem.tica dentro de la videograf.a mexicana contempor.nea. Inaugur. una l.nea de trabajo inusual y de profuso nivel experimental con el uso de c.maras filmadoras. Obras como Videodanza, viva videodanza o Autovideato, de 1979, o Mi co-ra-z.n, de 1986, resaltaron la puesta en escena de movimientos libres y osados y estimularon la expansi.n f.sica en tiempos y espacios singulares. Su obra abri. una serie de interrogantes sobre tem.ticas que ocuparon a las te.ricas feministas. Este trabajo procura trazar algunos se.alamientos te.ricos a partir de las modalidades con las que Pola exhibe e interpreta los cuerpos. Esos rasgos peculiares se enlazan con los desbordes y las din.micas que caracterizan los cuerpos presentes en sus videos, donde la materia, los fluidos org.nicos, las emociones y los movimientos f.sicos se desregulan y perturban las conductas normativas y las convenciones culturales. Para ello, se examinar.n documentos originales del Fondo Pola Weiss existente en el Museo Universitario de Arte Contempor.neo de la Universidad Nacional Aut.noma de M.xico, en pos de analizar su itinerario art.stico. Se considerar.n las reflexiones de Rebecca Schneider sobra la performance y las nociones fundamentales sobre la perspectiva de g.nero de Judith Butler, Carol Maier, Laura Mulvey y Nelly Richard. Finalmente, se arribar. a una serie de conclusiones que nos permitir.n articular los lazos entre la producci.n de la artista y los conceptos provenientes del feminismo. M.s all. de las connotaciones est.ticas, se aportar. una lectura renovada sobre Pola Weiss al subrayar el potencial cr.tico de su legado videogr.fico.</p><p> </p>
Sequencing of
FKS
Hot Spot 1 from Saprochaete capitata To Search for a Relationship to Reduced Echinocandin Susceptibility
Authors: Arrieta-Aguirre Inés , Menéndez-Manjón Pilar , Cuétara María Soledad , Fernández de Larrinoa Iñigo , García-Ruiz Juan Carlos , Moragues María Dolores 
Published: December 2017

ABSTRACT

Saprochaete capitata
, formerly known as
Geotrichum capitatum
, is an emerging fungal pathogen with low susceptibility to echinocandins. Here, we report the nucleotide sequence of the
S. capitata
hot spot 1 region of the
FKS
gene (
FKS
HS1), which codifies for the catalytic subunit of β-1,3-
d
-glucan synthase, the target of echinocandins. For that purpose, we first designed degenerated oligonucleotide primers derived from conserved flanking regions of the
FKS1
HS1 segment of 12 different fungal species. Interestingly, analysis of the translated
FKS
HS1 sequences of 12 isolates of
S. capitata
revealed that all of them exhibited the same F-to-L substitution in a position that is highly related to reduced echinocandin susceptibility.
Elucidating the Pharmacokinetics/Pharmacodynamics of Aerosolized Colistin against Multidrug-Resistant Acinetobacter baumannii and Klebsiella pneumoniae in a Mouse Lung Infection Model
Authors: Lin Yu-Wei , Zhou Qi Tony , Han Mei-Ling , Chen Ke , Onufrak Nikolas J. , Wang Jiping , Turnidge John D. , Howden Benjamin P. , Forrest Alan , Chan Hak-Kim , Li Jian 
Published: December 2017

ABSTRACT

The pharmacokinetics/pharmacodynamics (PK/PD) of aerosolized colistin was investigated against
Acinetobacter baumannii
and
Klebsiella pneumoniae
over 24 h in a neutropenic mouse lung infection model. Dose fractionation studies were performed over 2.64 to 23.8 mg/kg/day, and the data were fitted to a sigmoid inhibitory model. The area under the concentration-time curve over 24 h in the steady state divided by the MIC (AUC/MIC) in the epithelial lining fluid was the most predictive PK/PD index for aerosolized colistin against both pathogens. Our study provides important pharmacological information for optimizing aerosolized colistin.
Hyperbaric Oxygen Reduces Aspergillus fumigatus Proliferation
In Vitro
and Influences
In Vivo
Disease Outcomes
Authors: Dhingra Sourabh , Buckey Jay C. , Cramer Robert A. 
Published: December 2017

ABSTRACT

Recent estimates suggest that more than 3 million people have chronic or invasive fungal infections, causing more than 600,000 deaths every year.
Aspergillus fumigatus
causes invasive pulmonary aspergillosis (IPA) in patients with compromised immune systems and is a primary contributor to increases in human fungal infections. Thus, the development of new clinical modalities as stand-alone or adjunctive therapy for improving IPA patient outcomes is critically needed. Here we tested the
in vitro
and
in vivo
impacts of hyperbaric oxygen (HBO) (100% oxygen, >1 atmosphere absolute [ATA]) on
A. fumigatus
proliferation and murine IPA outcomes. Our findings indicate that HBO reduces established fungal biofilm proliferation
in vitro
by over 50%. The effect of HBO under the treatment conditions was transient and fungistatic, with
A. fumigatus
metabolic activity rebounding within 6 h of HBO treatment being removed.
In vivo
, daily HBO provides a dose-dependent but modest improvement in murine IPA disease outcomes as measured by survival analysis. Intriguingly, no synergy was observed between subtherapeutic voriconazole or amphotericin B and HBO
in vitro
or
in vivo
with daily HBO dosing, though the loss of fungal superoxide dismutase genes enhanced HBO antifungal activity. Further studies are needed to optimize the HBO treatment regimen and better understand the effects of HBO on both the host and the pathogen during a pulmonary invasive fungal infection.
Activation of Porcine Alveolar Macrophages by Actinobacillus pleuropneumoniae Lipopolysaccharide via the Toll-Like Receptor 4/NF-κB-Mediated Pathway
Authors: Li Bi , Fang Jing , Zuo Zhicai , Yin Sirui , He Tingting , Yang Mingxian , Deng Junliang , Shen Liuhong , Ma Xiaoping , Yu Shumin , Wang Ya , Ren Zhihua 
Published: December 2017

ABSTRACTActinobacillus pleuropneumoniaeis the causative agent of porcine contagious pleuropneumonia. Overproduction of proinflammatory cytokines, like interleukin-1β (IL-1β), IL-6, tumor necrosis factor alpha, and resistin, in the lung is an important feature ofA. pleuropneumoniaeinfection. These proinflammatory cytokines enhance inflammatory and immunological responses. However, the mechanism that leads to cytokine production remains unclear. As a major virulence factor ofA. pleuropneumoniae, lipopolysaccharide (LPS) may act as a potent stimulator of Toll-like receptor 4 (TLR4), triggering a number of intracellular signaling pathways that lead to the synthesis of proinflammatory cytokines. Porcine alveolar macrophages (PAMs) are the first line of defense against pathogenic microbes during pathogen invasion. The results of the present study demonstrate thatA. pleuropneumoniaeLPS induces PAMs to produce inflammatory cytokines in time- and dose-dependent manners. Moreover, PAMs were activated byA. pleuropneumoniaeLPS, resulting in upregulation of signaling molecules, including TLR4, MyD88, TRIF-related adaptor molecule, and NF-κB. In contrast, the activation effects ofA. pleuropneumoniaeLPS on PAMs could be suppressed by specific inhibitors, like small interfering RNA and Bay11-7082. Taken together, our data indicate thatA. pleuropneumoniaeLPS can induce PAMs to produce proinflammatory cytokines via the TLR4/NF-κB-mediated pathway. These findings partially reveal the mechanism of the overproduction of proinflammatory cytokines in the lungs of swine withA. pleuropneumoniaeinfection and may provide targets for the prevention ofA. pleuropneumoniae-induced pneumonia. All the data could be used as a reference for the pathogenesis of respiratory infection.
Protocol for developing a Database of Zoonotic disease Research in India (DoZooRI)
Authors: Chatterjee Pranab , Bhaumik Soumyadeep , Chauhan Abhimanyu Singh , Kakkar Manish 
Published: December 2017

IntroductionZoonotic and emerging infectious diseases (EIDs) represent a public health threat that has been acknowledged only recently although they have been on the rise for the past several decades. On an average, every year since the Second World War, one pathogen has emerged or re-emerged on a global scale. Low/middle-income countries such as India bear a significant burden of zoonotic and EIDs. We propose that the creation of a database of published, peer-reviewed research will open up avenues for evidence-based policymaking for targeted prevention and control of zoonoses.Methods and analysisA large-scale systematic mapping of the published peer-reviewed research conducted in India will be undertaken. All published research will be included in the database, without any prejudice for quality screening, to broaden the scope of included studies. Structured search strategies will be developed for priority zoonotic diseases (leptospirosis, rabies, anthrax, brucellosis, cysticercosis, salmonellosis, bovine tuberculosis, Japanese encephalitis and rickettsial infections), and multiple databases will be searched for studies conducted in India. The database will be managed and hosted on a cloud-based platform called Rayyan. Individual studies will be tagged based on key preidentified parameters (disease, study design, study type, location, randomisation status and interventions, host involvement and others, as applicable).Ethics and disseminationThe database will incorporate already published studies, obviating the need for additional ethical clearances. The database will be made available online, and in collaboration with multisectoral teams, domains of enquiries will be identified and subsequent research questions will be raised. The database will be queried for these and resulting evidence will be analysed and published in peer-reviewed journals.
Informing future research for carriage of multiresistant Gram-negative bacteria: problems with recruiting to an English stool sample community prevalence study
Authors: Lecky Donna M , Nakiboneka-Ssenabulya Deborah , Nichols Tom , Hawkey Peter , Turner Kim , Chung Keun-Taik , Thomas Mike , Thomas Helen Lucy , Xu McCrae Li , Shabir Sahida , Manzoor Susan , Alvarez-Buylla Adela , Smith Steve , McNulty Cliodna 
Published: December 2017

ObjectivesThis study aims to highlight problems with recruiting to an English stool sample community prevalence study. It was part of a larger cross-sectional research to determine the risk factors for the presence of extended-spectrum beta-lactamase and carbapenemase-producing coliforms in stool samples of the asymptomatic general English population.SettingFour National Health Service primary care trusts (PCTs) of England representing a different section of the population of England: Newham PCT; Heart of Birmingham Teaching PCT; Shropshire County PCT; and Southampton City PCT.ParticipantsSixteen general practices across the four PCTs were purposefully selected. After stratification of GP lists by age, ethnicity and antibiotic use, 58 337 randomly selected patients were sent a postal invitation.Patients who had died, moved to a different surgery, were deemed too ill by their General Practitioner or hospitalised at the time of mailing were excluded.ResultsStool and questionnaire returns varied by area, age, gender and ethnicity; the highest return rate of 27.3% was in Shropshire in the age group of over 60 years; the lowest, 0.6%, was in Birmingham in the age group of 18–39 years. Whereas only 3.9%(2296) returned a completed questionnaire and stool sample, 94.9% of participants gave permission for their sample and data to be used in future research.ConclusionResearchers should consider the low stool specimen return rate and wide variation by ethnicity and age when planning future studies involving stool specimen collection. This is particularly pertinent if the study has no health benefit to participants. Further research is needed to explore how to improve recruitment in multicultural communities and in younger people.
Rationale and design of GENEiUS: a prospective observational study on the genetic and environmental determinants of body mass index evolution in Canadian undergraduate students
Authors: Morassut Rita E , Langlois Christine , Alyass Akram , Ishola Adeola F , Yazdi Fereshteh T , Mayhew Alexandra J , Reddon Hudson , MacKillop James , Pigeyre Marie , Meyre David 
Published: December 2017

IntroductionObesity is a global epidemic and is a risk factor for developing other comorbidities. Young adulthood is a critical period for body weight change and establishing healthy lifestyle behaviours. The ‘Freshman 15’ suggests that undergraduate students gain 15 lbs (6.8 kg) during their first year of university, although evidence estimates a more modest weight gain of approximately 3–5 lbs (1.4–2.3 kg). Previous studies have only investigated weight change in the first year and do not study potential risk factors. Genetic and EnviroNmental Effects on weight in University Students (GENEiUS) is a prospective observational study which will investigate the environmental and biological determinants of weight change in undergraduate students over 4 years.Methods and analysisThe GENEiUS study will recruit 2500 multiethnic undergraduates aged 17–25 years at McMaster University at the start of their first year and will follow them every 6 months for 4 years. Primary outcomes are obesity traits: body mass index, waist circumference, waist-to-hip ratio, body fat mass and body fat percentage. The contribution of well-established and novel genetic variants for obesity traits and heritability values will be derived from whole-genome single-nucleotide polymorphism genotyping arrays. Civil status, age, sex, ethnicity, length of residence in Canada, religiosity, energy intake, physical activity, exercise motivation, electronic screen time, sleep patterns, history of assault, smoking status, alcohol consumption, medication and drug use, stress, impulsivity, body image perception, self-esteem, anxiety, eating disorders and depression will be investigated for their effect on obesity traits. The findings of the GENEiUS study will be used to help design obesity prevention programme in North American universities with multiethnic populations.Ethics and disseminationEthical approval of the study protocol has been obtained from the Hamilton Integrated Research Ethics Board. Study results will be disseminated through scientific publications, scholarly meetings, and collaborative meetings with university administration and student groups.
Study of coherent beam–beam instability in CEPC-H and Z
Authors: Ohmi Kazuhito 
Published: December 2017

Design work using beam–beam simulation has been done since starting the CEPC and Future Circular Collider (FCC) proposals. In recent [Formula: see text] colliders, a collision scheme with a large crossing angle is popular to overcome the hourglass effect. The crab waist scheme is adopted to further boost luminosity performance. Weak–strong simulations were mainly used in the early stage. Strong–strong simulations have been done since last year for the collision with a large crossing angle. Coherent beam–beam instability has been seen in the simulation for FCC. We discuss the instability for the CEPC. a a A general introduction to the CEPC can be found in Ref. 1.
The Legislation of Leviticus 12 in Light of Ancient Embryology
Authors: Thiessen Matthew 
Published: December 2017

Abstract
Interpreters have provided numerous unsatisfactory reasons for why priestly literature stipulates that women endure a longer impurity after the birth of a girl than they endure after the birth of a boy. This article situates Leviticus 12 within a wide range of medical discourses, found in Hittite, Greek, Roman, Jewish, and Christian literature, in order to illuminate the priestly rationale behind this legislation. It demonstrates that these differing periods of ritual impurity relate to ancient medical beliefs that females developed more slowly than did males. These different articulation rates were believed to result in different lengths of postpartum lochial discharge, which meant that the new mother suffered different lengths of ritual impurity based on the sex of the newborn child.
Edom, Judah, and Converse Constructions of Israeliteness in Genesis 36
Authors: Nash Dustin 
Published: December 2017

Abstract
Genesis 36 contains a distinctively large and heterogeneous body of genealogical materials pertaining to Esau and the kingdom of Edom. The present study suggests that the chapter reached its unique shape as the result of a specifically Judahite discursive project. In particular, a scribe expanded a preexisting priestly genealogy of Esau in order to create a robust boundary between entities defined as Edom and Israel. New interpretations of archaeological evidence from southern Jordan and the Negev reveal the context of dynamic interaction and fluid identities that likely prompted this expansion. The resulting text rejects memories of affiliation between Negevite and south Jordanian peoples in order to elevate Judah’s claim to the name and identity of Israel.
In Search of True-ness: Dialogue Between Political Localism and Theological Ecumenism in Post-Umbrella Movement
Authors: Kung Lap Yan 
Published: December 2017

Abstract
Seeking for true-ness is the core concern of the people of Hong Kong during the Umbrella Movement. That search starts from the political structure (true universal suffrage), and continues through into the formation of identity (true Hongkongese). This article illustrates how the Umbrella Movement has provided the people of Hong Kong with an experience of a truthful politics which is different from the current realpolitik. It sets out to see Hong Kong as their homeland, while developing a new language in terms of political localism. Nevertheless, there is a tendency for such political localism to become too narrow, exclusive and sentimental. The ecumenicity of the church interpreted in the light of Wolfhart Pannenberg’s theology is a different social imaginary. It can challenge both the inclination to narrowness and exclusivism of political localism, and the authoritarianism of the Chinese authorities. It possesses the potential to enrich the people of Hong Kong by allowing them to see that the unity of humankind (creation) is the ground of politics.
Special Issue: International Investment Arbitration in Southeast Asia
Authors: Nottage Luke , Thanitcul Sakda 
Published: December 2017

Abstract
The dynamic economies of the Association of Southeast Asian Nations (ASEAN) have individually concluded many standalone bilateral investment treaties (BITs) and a growing number of bilateral and regional free trade agreements (FTAs), supplemented by intra-ASEAN and ‘ASEAN+’ agreements. These aim to facilitate and protect burgeoning foreign direct investment (FDI) flows, outlined in Part 2, including large outflows recently from several states. Part 3 outlines treaty-making trends, including considerable consistency from many member states as well as some interesting innovations, against the backdrop of persistent problems of poor governance. Part 4 highlights nonetheless the relative paucity of investor-state dispute settlement (ISDS) claims against ASEAN member states, with only a few adverse awards, which helps explain why treaty-based ISDS has not been abandoned. Part 5 also notes several contributions from this ISDS case law to international investment law, and Southeast Asia’s potential to keep influencing its trajectory.
International Investment Arbitration in Myanmar: Bounded Rationality, But Not as We Know It
Authors: Bonnitcha Jonathan 
Published: December 2017

Abstract
In 2011, following almost fifty years of one-party military rule, Myanmar began a process of transition toward democracy. Alongside this process, the Government of Myanmar is pursuing a variety of reforms in the hope of attracting new foreign investment. This article examines elements of the national and international legal environment governing foreign investment in Myanmar. The focus is on Myanmar’s current approach to investment treaties and Myanmar’s experience of investor-state arbitration under such treaties to date, although the article also reviews Myanmar’s national laws that are relevant to international investment arbitration, notably its laws on foreign investment and on arbitration. The article highlights Myanmar’s position to date as a ‘rule-taker’ in the investment treaty regime. It draws attention to important differences between Myanmar’s experience with investment treaties and the experiences of other developing countries, as well as possible points of similarity.
Self-Other Relationship, History and Interpretation
Authors: Sarma Arup Jyoti 
Published: December 2017

Abstract
This paper offers a critical appraisal of Gadamer’s dialogical philosophy of the self-other relationship within the context of interpretation and historical consciousness. According to Gadamer hermeneutics is a theory of interpretation or, rather, the art of interpretation. The task of philosophical hermeneutics is to narrate an ontology of human understanding with the ethical intent of restoring to interpretation a greater sense of “integrity.” The “hermeneutic universe” belongs to the individual worldviews whose structure and content are constructed on the basis of historical precedents. Gadamer situates these precedents in historicity and the tradition of culture, which are resources for their unique interpretations. Gadamer claims that interpretative understanding encounters the other in the dialogical “play” (Spiel) of an ever-unfinished event. The self and the other belong to the horizon of historical consciousness, and it is through this common horizon that the alterity of the other comes into expression.
A Comparison of Ketoprofen and Diclofenac for Acute Musculoskeletal Pain Relief: a Prospective Randomised Clinical Trial
Authors: Ng P , Kam Cw , Yau Hh 
Published: December 2017

ObjectivesTo compare the efficacy and adverse effects of Ketoprofen and Diclofenac in the treatment of acute musculoskeletal pain.MethodsIn a prospective randomised clinical trial, patients admitted to an emergency department with acute musculoskeletal injuries requiring intramuscular (IM) injection for pain treatment were enrolled. The target study patients were Chinese adults who suffered from any musculoskeletal injuries of less than 12 hours. They received either 100 mg of Ketoprofen or 75 mg of Diclofenac. Pain was assessed by a 10-point visual analog score (VAS) and evaluations were performed at 30-minute intervals from treatment. Rescue analgesic was given if insufficient analgesia was achieved by one hour. The outcomes and the adverse effects were recorded.ResultsWe recruited 77 cases in the Diclofenac group and 74 cases in the Ketoprofen group. The demographic data with regards to age, sex and patterns of injury were comparable in both groups. Following the administration of treatment, both groups showed highly statistically significant (P<0.001) reduction in pain level at 30-minute and 60-minute intervals. Comparing the mean decrease of pain level, there was no statistically significant difference between the two groups at 30-minute interval (P=0.6) and 60-minute interval (P=0.5). In each group, there was one patient experiencing skin rash after treatment. Four patients in the Ketoprofen group and one in Diclofenac group required rescue medicine. With respect to the number of admission following treatment, there was no statistically significant difference between the two groups.ConclusionsKetoprofen and Diclofenac are equally effective and safe in the treatment of acute musculoskeletal pain in Hong Kong Chinese population.