bluuebunny/crossref_metadata_2025_split huggingface dataset:
Der ideale Ort?
Authors: Strauss Alexander 
Published: December 2017

Liebe Leserin, lieber Leser,Schwangerschaft und Geburt sind als ursprüngliche und sehr intime Lebensabläufe nicht mit Behandlung erfordernden Gesundheitsstörungen gleichzusetzen. Ein möglichst ungestörter Verlauf der Entbindung mit Eins-zu-Eins-Betreuung der Gebärenden durch ihre Hebamme hilft geburtshilfliche Komplikationen und konsekutive Eingriffe zu vermeiden. Prozesszufriedenheit der Schwangeren bzw. der werdenden Eltern wird dabei allerdings nicht nur durch augenscheinlich leicht objektivierbare Qualitätskriterien abgebildet. Geburtshilfliche Sicherheit von Mutter und Kind unter Wahrung größtmöglicher Selbstbestimmung der Schwangeren markieren in diesem Kontext unverrückbare Zielpunkte. Dies umfasst damit auch die grundsätzliche Freiheit der werdenden Mutter, über den Ort der Geburt unabhängig entscheiden zu können. Das individuelle Setting wird dabei vom mütterlichen Bestreben getragen sein, in einer geschützten (häuslichen) Umgebung und in Tuchfühlung mit supportiv wirkenden Personen ihr Kind zur Welt zu bringen. Äußere Stellgrößen wie räumliche Gegebenheiten, Licht, Geräusche, Stimmen nehmen dabei ebenso wie Achtsamkeit auf Intimsphäre, Begleitung oder Bewegungsmöglichkeit den Charakter maßgeblicher Entscheidungsgrößen an.
CpdA is involved in amino acid metabolism in Shewanella oneidensis MR-1
Authors: Kasai Takuya , Kouzuma Atsushi , Watanabe Kazuya 
Published: December 2017

Abstract
Cyclic 3′,5′-adenosine monophosphate (cAMP) phosphodiesterase (CPD) is an enzyme that catalyzes the hydrolysis of cAMP, a signaling molecule affecting diverse cellular and metabolic processes in bacteria. Some CPDs are also known to function in cAMP-independent manners, while their physiological roles remain largely unknown. Here, we investigated physiological roles of CPD in Shewanella oneidensis MR-1, a model environmental bacterium, and report that CPD is involved in amino-acid metabolism. We found that a CPD-deficient mutant of MR-1 (ΔcpdA) showed decreased expression of genes for the synthesis of methionine, S-adenosylmethionine, and histidine and required these three compounds to grow in minimal media. Interestingly, deletion of adenylate cyclases in ΔcpdA did not restore the ability to grow in minimal media, indicating that the amino acid requirements were not due to the accumulation of cAMP. These results suggest that CPD is involved in the regulation of amino acid metabolism in MR-1 in a cAMP-independent manner.
Effects of Thermal Resistance on One-Dimensional Thermal Analysis of the Epidermal Flexible Electronic Devices Integrated with Human Skin
Authors: Li He , Cui Yun 
Published: December 2017

Abstract
Nowadays, flexible electronic devices are increasingly used in direct contact with human skin to monitor the real-time health of human body. Based on the Fourier heat conduction equation and Pennes bio-heat transfer equation, this paper deduces the analytical solutions of one - dimensional heat transfer for flexible electronic devices integrated with human skin under the condition of a constant power. The influence of contact thermal resistance between devices and skin is considered as well. The corresponding finite element model is established to verify the correctness of analytical solutions. The results show that the finite element analysis agrees well with the analytical solution. With bigger thermal resistance, temperature increase of skin surface will decrease. This result can provide guidance for the design of flexible electronic devices to reduce the negative impact that exceeding temperature leave on human skin.
The potential of a human rights approach for accelerating the implementation of comprehensive restrictions on the marketing of unhealthy foods and non-alcoholic beverages to children
Authors: Granheim Sabrina Ionata , Vandevijvere Stefanie , Torheim Liv Elin 
Published: December 2017

Summary
Overweight and obesity in children is rising at the global level, particularly in low- and middle-income countries. Among the causes for this increase is the marketing of unhealthy food and beverage products, which affects children’s food preferences, purchasing requests and consumption patterns. The need to address harmful marketing to children has been recognized at the World Health Organization, with Member States having agreed in 2010 to implement a set of recommendations to restrict such practices. Concurrently, there is an increasing understanding of unhealthy food and malnutrition as human rights concerns. This paper explores the potential of existing legally and non-legally binding human rights instruments for accelerating the implementation of comprehensive restrictions to reduce harmful marketing of unhealthy foods and beverages to children. Four relevant themes were identified in existing human rights instruments: (i) the best interest of the child should be considered above all other interests; (ii) the rights to health and adequate food cannot be realized without supportive healthy environments; (iii) children should be protected from economic exploitation; and (iv) the persuasive marketing of unhealthy food and beverage products is explicitly recognized as a threat to the rights to food and health. In conclusion, existing human rights instruments could be harnessed to advance public health measures to restrict the marketing of unhealthy food and beverage products to children. Policy-makers and advocates should draw from these instruments and refer to State’s obligations within international and domestic human rights law to strengthen their efforts to restrict harmful marketing practices to children.
Stability and constrained control for positive two-dimensional systems with delays in the second FM model
Authors: Shen Jian , Wang Weiqun 
Published: December 2017

Abstract
This paper addresses the stability and control problem of linear positive two-dimensional discrete-time systems with multiple delays in the second Fornasini–Marchesini model. The contribution lies in three aspects. First, a novel proof is provided to establish necessary and sufficient conditions of asymptotic stability for positive two-dimensional delayed systems. Then, a state-feedback controller is designed to ensure the non-negativity and stability of the closed-loop systems. Finally, a sufficient condition for the existence of constrained controllers is developed under the additional constraint of bounded control, which means that the control inputs and the states of the closed-loop systems are bounded. Two examples are given to validate the proposed methods.
A Sharp Version of the Hörmander Multiplier Theorem
Authors: Grafakos Loukas , Slavíková Lenka 
Published: December 2017

AbstractWe provide an improvement of the Hörmander multiplier theorem in which the Sobolev space ${{L^{r}_{s}}}(\mathbb R^{n})$ with integrability index r and smoothness index s > n/r is replaced by the Sobolev space with smoothness s built upon the Lorentz space $L^{n/s,1}(\mathbb R^{n})$.
Transforming the Role of the Clinical Faculty Coordinator in the Dedicated Education Unit
Authors: Auxier Nicole , Simpson Holly 
Published: December 2017

Abstract
The dedicated education unit (DEU) clinical education model has been identified nationally as an innovative model for clinical nursing education. This article identifies the core values of the DEU clinical faculty coordinator role and describes the transformation of this role across three clinical models. The role has been adapted to fit the needs of acute care, post-acute care, and community nursing DEU models, meeting the needs of the clinical educational environment and clinical staff as well as student learning outcomes.
Accessory Auricles: Systematic Review of Definition, Associated Conditions, and Recommendations for Clinical Practice
Authors: Amirhassankhani Sasan , Lloyd Mark S. 
Published: December 2017

Abstract
Accessory auricles are rare congenital abnormalities embryologically derived from the first branchial arch. Presentation may be variable with locations grouped into anatomical zones based on the frequency of location found in the literature. This study reviewed the papers between 1981 and 2017. Findings included an association with syndromes including Goldenhar, VACTERL, Treacher–Collins, Townes–Brocks, and Wolf–Hirschhorn. Based on histological and embryological evidence, the term “accessory auricle” is best used as an umbrella term to define this difference. Finally, indications are provided for imaging and laboratory investigations to guide the physician treating patients with accessory auricles.
Primary Closure of Oroantral Communication Using Pedicled Buccal Fat Pad Following Maxillary Cyst Enucleation
Authors: Emes Yusuf , Aga Uğur , Cesur Anil , Soluk-Tekkesin Merva , Aybar Büket , Alatli Canan 
Published: December 2017

Abstract
Odontogenic keratocyst (OKC) is a clinically aggressive developmental odontogenic cyst with a high recurrence rate as 62%. Oroantral communication (OAC) is a gateway through the maxillary sinus and the oral cavity, which, if not treated, will develop into oroantral fistula or chronical sinus diseases. Different methods for closure of OAC were described but only few of them have common usage. In recent years, the use of a pedicled buccal fat pad (BFP) in closure of large oroantral defects has been become popular. In our patient, the OAC resulted from the surgical removal of OKC was closed with BFP.
Coalescence and linkage disequilibrium in facultatively sexual diploids
Authors: Hartfield Matthew , Wright Stephen I. , Agrawal Aneil F. 
Published: December 2017

AbstractUnder neutrality, linkage disequilibrium (LD) results from physically linked sites having non-independent coalescent histories. In obligately sexual organisms, meiotic recombination is the dominant force separating linked variants from one another, and thus in determining the decay of LD with physical distance. In facultatively sexual diploid organisms that principally reproduce clonally, mechanisms of mitotic exchange are expected to become relatively more important in shaping LD. Here we outline mathematical and computational models of a facultative-sex coalescent process that includes meiotic and mitotic recombination, via both crossovers and gene conversion, to determine how LD is affected with facultative sex. We demonstrate that the degree to which LD is broken down by meiotic recombination simply scales with the probability of sex if it is sufficiently high (much greater than 1/NforNthe population size). However, with very rare sex (occurring with frequency on the order of 1/N), mitotic gene conversion plays a particularly important and complicated role because it both breaks down associations between sites and removes within-individual diversity. Strong population structure under rare sex leads to lower average LD values than in panmictic populations, due to the influence of low-frequency polymorphisms created by allelic sequence divergence acting in individual subpopulations. These analyses provide information on how to interpret observed LD patterns in facultative sexuals, and determine what genomic forces are likely to shape them.
Clinically Important sex differences in GBM biology revealed by analysis of male and female imaging, transcriptome and survival data
Authors: Yang Wei , Warrington Nicole M. , Taylor Sara J. , Carrasco Eduardo , Singleton Kyle W. , Wu Ningying , Lathia Justin D. , Berens Michael E. , Kim Albert H. , Barnholtz-Sloan Jill S. , Swanson Kristin R. , Luo Jingqin , Rubin Joshua B 
Published: December 2017

AbstractSex differences in the incidence and outcome of human disease are broadly recognized but in most cases not adequately understood to enable sex-specific approaches to treatment. Glioblastoma (GBM), the most common malignant brain tumor, provides a case in point. Despite well-established differences in incidence, and emerging indications of differences in outcome, there are few insights that distinguish male and female GBM at the molecular level, or allow specific targeting of these biological differences. Here, using a quantitative imaging-based measure of response, we found that temozolomide chemotherapy is more effective in female compared to male GBM patients. We then applied a novel computational algorithm to linked GBM transcriptome and outcome data, and identified novel sex-specific molecular subtypes of GBM in which cell cycle and integrin signaling were identified as the critical determinants of survival for male and female patients, respectively. The clinical utility of cell cycle and integrin signaling pathway signatures was further established through correlations between gene expression and in vitro chemotherapy sensitivity in a panel of male and female patient-derived GBM cell lines. Together these results suggest that greater precision in GBM molecular subtyping can be achieved through sex-specific analyses, and that improved outcome for all patients might be accomplished via tailoring treatment to sex differences in molecular mechanisms.One Sentence SummaryMale and female glioblastoma are biologically distinct and maximal chances for cure may require sex-specific approaches to treatment.
A solution to the hand-eye calibration in the manner of the absolute orientation problem
Authors: Deniz Cengiz , Cakir Mustafa 
Published: December 2017

Purpose
This paper aims to introduce a simple hand-eye calibration method that can be easily applied with different objective functions.

Design/methodology/approach
The hand-eye calibration is solved by using the closed form absolute orientation equations. Instead of processing all samples together, the proposed method goes through all minimal solution sets. Final result is chosen after evaluating the solution set for arbitrary objectives. In this stage, outliers can be excluded optionally if more accuracy is desired.

Findings
The proposed method is very flexible and gives more accurate and convenient results than the existing solutions. The mathematical error expression defined by the calibration equations may not be valid in practice, where especially systematic distortions are present. It is shown in the simulations that the solution which results the least mathematical error in systems may have incorrect, incompatible results in the presence of practical demands.

Research limitations/implications
The performance of the calibration performed with the proposed method is compared with the reference methods in the literature. When the back-projection error is benchmarked, which corresponds to the point repeatability, the proposed approach is considered as the most successful method among all others. Due to its robustness, it is decided to make tooling-sensor calibrations by the recommended method, in the robotic non-destructive testing station in Ford-OTOSAN Kocaeli Plant Body Shop Department.

Originality/value
Arranging the well-known AX = XB calibration equation in quaternion representation as Q_A = Q_x × Q_B × Q_x reveals another common spatial rotation equation. In this way, absolute orientation solution satisfies the hand-eye calibration equations. The proposed solution is not presented in the literature as a standalone hand-eye calibration method, although some researchers drop a hint to the relative formulations.
Growth in containership sizes to be stopped?
Authors: Malchow Ulrich 
Published: December 2017

Purpose
The increase of containership sizes driven by the need to create greater economies of scale seems to be an endless process. Vessels of more than 21,000 TEU are presently on order. The purpose of this paper is to question whether a positive effect still remains at present mega ship sizes and, even if this was the case, whether such presumably small effect would be outweighed by costly operational impacts for the lines and the ports out of the huge ship sizes.

Design/methodology/approach
The effect of increasing ship sizes on the three major cost items in container shipping have been investigated by extrapolating founded regression curves, applying respective physical laws and referring lumpsum crewing cost (as the major part of the vessel’s running costs) to various ship sizes.

Findings
In this paper, it is shown that further effects of lower slot costs lessen while ships get larger. Hence, a further increase in ship sizes would not significantly reduce transport costs anymore. In contrast, the necessary efforts to prepare the ports for ships of ever-increasing size are growing over proportionally with every additional metre of draught and/or beam. It is shown that an ongoing increase of containership sizes, e.g. in the Europe-Far East trade, does not bring any further benefit, neither for the ports and their terminals nor even for the lines itself and not even for the shippers! It is an amazing mechanism that all stakeholders act rationally on their own, but the overall effect for all of them (including the public) has turned into negative.

Originality/value
The results may pave the way for a closer cooperation among ports, e.g. within the Hamburg-Le Havre range. Ports and terminals may see the opportunity to escape the spiral of ongoing efforts for deepening and widening the fairways and installing ever-bigger gantry cranes by agreeing on a joint policy with regard to maximum ship size.
Internationalisation within liner shipping
Authors: Prockl Günter , Kinra Aseem , Kotzab Herbert 
Published: December 2017

PurposeContainer shipping is generally considered a global business. This truth may not hold from a single-company perspective. The companies’ physical operation networks show that container carriers operate differently and follow different paths in their internationalisation development. Additionally, the degree of internationalisation, measured on the basis of sea-oriented operations, differs from that measured according to land-oriented front-end marketing and sales activities. The purpose of this study is to further examine the internationalisation patterns of shipping lines.Design/methodology/approachAn examination of the front-end activities and the structures of leading container-shipping companies is conducted. The sales office networks of the sector’s 20 largest companies worldwide (by twenty-foot equivalent unit capacity) are analysed as key indicators. The numbers of sales offices are measured by analysing the websites of the sample (20 companies), as well as annual reports and other publicly available data sources.FindingsThe findings show that not all shipping companies are international, by virtue of the industry. While it is difficult to observe differences in the overall patterns of the sales networks at a macro level, some companies differ in their activities. The data set also shows that market share and total capacity are not necessarily good indicators of a carrier’s worldwide presence.Research limitations/implicationsThis research is based on secondary data. Other important transactional and market-oriented considerations should be examined before drawing conclusions about the internationalisation of container-shipping companies and of the industry.Originality/valueThis paper contributes to the relevant existing research, particularly by adding its view on the demand-oriented criteria as suggested by Dunning and Lundan (2008).
Formate hydrogenlyase and formate secretion ameliorate H2 inhibition in the hyperthermophilic archaeon Thermococcus paralvinellae
Authors: Topçuoğlu Begüm D. , Meydan Cem , Orellana Roberto , Holden James F. 
Published: December 2017

SummarySome hyperthermophilic heterotrophs in the genus Thermococcus produce H2 in the absence of S° and have up to seven hydrogenases, but their combined physiological roles are unclear. Here, we show which hydrogenases in Thermococcus paralvinellae are affected by added H2 during growth without S°. Growth rates and steady‐state cell concentrations decreased while formate production rates increased when T. paralvinallae was grown in a chemostat with 65 µM of added H2(aq). Differential gene expression analysis using RNA‐Seq showed consistent expression of six hydrogenase operons with and without added H2. In contrast, expression of the formate hydrogenlyase 1 (fhl1) operon increased with added H2. Flux balance analysis showed H2 oxidation and formate production using FHL became an alternate route for electron disposal during H2 inhibition with a concomitant increase in growth rate relative to cells without FHL. T. paralvinellae also grew on formate with an increase in H2 production rate relative to growth on maltose or tryptone. Growth on formate increased fhl1 expression but decreased expression of all other hydrogenases. Therefore, Thermococcus that possess fhl1 have a competitive advantage over other Thermococcus species in hot subsurface environments where organic substrates are present, S° is absent and slow H2 efflux causes growth inhibition.
Collaborative model for training and credentialing point‐of‐care ultrasound: 6‐year experience and quality outcomes
Authors: Cormack Carolynne J , Coombs Peter R , Guskich Kate E , Blecher Gabriel E , Goldie Neil , Ptasznik Ronnie 
Published: December 2017

AbstractIntroductionPoint‐of‐care ultrasound (PoCUS) is a rapidly growing area, providing physicians with a valuable diagnostic tool for patient assessment. This paper describes a collaborative model, utilising radiology department ultrasound expertise, to train and credential physicians in PoCUS. A 6‐year experience of the implementation and outcomes of the programme established within the emergency departments of a large, multi‐campus hospital network are presented.MethodsA collaborative model was initially developed and implemented between radiology and emergency departments. Key elements of the programme included hospital executive support, close collaboration with stakeholders, resource allocation, appointment of a sonographer educator, clear scope of practise and robust quality processes.ResultsParticipation grew from 36 emergency physicians in 2011 to 96 physicians in 2016. A total 11064 scans were logged with the programme in the 6‐year period. Routine quality audit of 61.8% (6836/11064) of all scans included 2836 Focussed Assessment by Sonography in Trauma (FAST) and 1422 Abdominal Aortic Aneurysm (AAA) examinations. False‐positive or false‐negative diagnoses occurred in 3.6% (102/2836) FAST and 1.3% (19/1422) AAA cases. No adverse clinical outcomes were reported to involve programme‐compliant scans.ConclusionA collaborative model to train and credential physicians in PoCUS has been successfully implemented. The programme grew significantly, produced excellent quality outcomes and resolved many issues of potential conflict related to PoCUS.