bluuebunny/crossref_metadata_2025_split huggingface dataset:
Actors with intellectual disabilities in mental health simulation training
Authors: Attoe Chris , Billon Gregoire , Riches Samantha , Marshall-Tate Karina , Wheildon James , Cross Sean 
Published: June 2017

Purpose
People with intellectual disabilities experience poorer health outcomes than the general population, and a significantly increased risk of mental health comorbidity. Their access to healthcare has been consistently shown as inadequate, and their access to mental health support is still largely wanting. Adequate training and education should improve these shortcomings but there is limited evidence available as to the best way to achieve this. The paper aims to discuss these issues.

Design/methodology/approach
This paper reports on the co-production and co-delivery of a simulation training course to support healthcare professionals to provide care for people with intellectual disabilities, with a particular focus on their mental health needs. This training was designed with actors with intellectual disabilities, who participated as simulated patients in scenarios during the course and subsequently provided feedback on their experience.

Findings
This paper focusses on the positive experiences of the simulated patients, reporting on and interpreting their direct feedback on their experience of contributing to the development and delivery of the course and being involved as co-educators.

Originality/value
It is highlighted that the co-production and delivery of this simulation training with people with intellectual disabilities has the potential to realise some of the key principles called upon when attempting to improve how they are treated, by illustrating concrete participation, independence, and access to fulfilling lives. The value and benefits of interprofessional education to achieve these educational aims is further highlighted, particularly for the potential to generate a sense of shared responsibility within mainstream services in caring for people with intellectual disabilities.
Reconstructing lives: transformative services for human trafficking survivors
Authors: Loomba Arvinder P.S. 
Published: June 2017

Purpose
The purpose of this paper is to introduce a transformative service-based model, which analyzes tripartite service interaction logics among trafficking survivors, anti-trafficking agencies and the community during a process of actively- and passively transformative exchanges. It aims to help researchers and practitioners better understand services that facilitate reintegration of trafficking survivors into society.

Design/methodology/approach
Using theory development from sociological and liminality schools of thought, this paper explores a variety of coping strategies that anti-trafficking agencies can offer human-trafficking survivors in post-trafficking service settings.

Findings
A novel transformative service-based framework extends current conceptualizations of social and service exchange in a tripartite interaction setting. Anti-trafficking agencies can create a supportive community environment to offer trafficking survivors passively transformative services and to cultivate and nurture their coping skills towards reintegration into society.

Research limitations/implications
Important implications for transformative service-based theory and practice of serving trafficking survivors are discussed. In addition, the study limitations are addressed.

Practical implications
The transformative service-based model analyzes tripartite service interaction logics during a process of exchanges between trafficking survivors, anti-trafficking agency and community ecosystem to achieve meaningful post-trafficking reintegration into society.

Social implications
Using the transformative service model, community ties need to be re-established for trafficking survivors to achieve successful reintegration into society, and for communities to heal and restore human dignity.

Originality/value
This research proposes a new framework for actively- and passively-transformative service logic for anti-trafficking agencies to offer assistance to trafficking survivors, based on sociological and liminality schools of thought.
An exploration of servicescapes’ exclusion and coping strategies of consumers with “hidden” auditory disorders
Authors: Beudaert Anthony , Gorge Hélène , Herbert Maud 
Published: June 2017

Purpose
The purpose of this study is both to explore how people with “hidden” auditory disorders experience exclusion in servicescapes and to unfold the coping strategies they set up to deal with it.

Design/methodology/approach
Findings from 15 semi-structured interviews and participant observations with individuals suffering from auditory disorders are presented through the paper.

Findings
The findings indicate that individuals with auditory disorders deploy three types of coping strategies when exposed to sensory overload in servicescapes: choosing between physical servicescapes, opting for electronic devices and e-servicescapes and delegating shopping to relatives.

Practical implications
The study underlines how, through temporary or permanent modifications of servicescape cues, service providers give consumers opportunities to bypass situations involving sensory overload. Implications for e-servicescapes and public policy are also raised.

Originality/value
The findings reveal how the coping strategies used by individuals with auditory disorders contribute to their exclusion from the marketplace on the basis of both individual characteristics and types of servicescapes.
Responding to the global skills crisis
Authors: King Michael , Marshall Anthony , Zaharchuk David 
Published: June 2017

Purpose
An IBM survey of business, government and education leaders concluded that if left unresolved, an emerging global skills crisis will likely have profound effects on businesses and economies worldwide.

Design/methodology/approach
To gauge current skills challenges and assess future needs, the IBM Institute for Business Value in cooperation with Oxford Economics surveyed more than 5,600 global executives representing 18 industries and 48 countries

Findings
Fifty-five percent of all executives surveyed conclude that inadequate investment from private industry is the most important challenge to overcome in addressing skills development in the future.

Practical implications
Personalized learning, powered by data-driven cognitive technologies, can enable personalized education – allowing individuals to readily take more responsibility over their skills future and improve outcomes for stakeholders across the business ecosystem.

Originality/value
Sixty-nine percent of industry executives from outperforming companies…indicate their organizations are already collaborating with ecosystem partners to address skills-related issues, as opposed to less than half of lower performing businesses.
Livelihoods and Child Welfare among Poor Rural Farmers in East Africa
Authors: Inder Brett , Kabore Carolyn , Nolan Sharna , Cornwell Katy , Contreras Suarez Diana , Crawford Anne , Kamara Joseph K. 
Published: June 2017

AbstractThis paper explores aspects of household livelihoods and welfare among poor rural farmers in Kenya, Uganda and Tanzania. The models use data from an extensive cross‐sectional household survey undertaken in 2013 of over 3,500 rural households. Interest is in identifying the main input constraints to improving farm production, with a particular focus on labour constraints, and the impacts of farm production on the well‐being of children — their food security, resilience and engagement in school. The results show low agricultural productivity, and that yields per hectare decline significantly with land size. This is consistent with poor quality land and a labour constraint in agricultural activity: there is insufficient return on labour to justify further investment of effort to cultivate the land, given the typically low‐input, labour‐intensive farming methods. Food shortage models also show that adult labour is relatively unproductive: having more adults in the household produces little reduction in the incidence of food shortages. Overall the results suggest some directions for development interventions, by highlighting that the critical issue for economic and social development among these communities is to improve the productivity of both land and labour.
In Search of Rural Entrepreneurship: Non‐farm Household Enterprises (NFEs) as Instruments of Rural Transformation in Ethiopia
Authors: Alemu Abebe Ejigu , Adesina Jimi O. 
Published: June 2017

AbstractSub‐Saharan Africa is mainly agricultural and rural transformation remains slow owing to weak market‐orientation and entrepreneurship development. This study aims at investigating determinants of households’ enterprise engagement and effect on livelihood. Logit model and propensity score matching were employed to analyse data captured from 415 households in Ethiopia. The empirical model reveals that education, cooperatives, socio‐economy, access to transport, communication, credit, and FTC were drivers of households’ engagement in NFE. Livelihood was also significantly better for engaged households. It is suggested that policies to improve infrastructure, credit and extension, and promote rural cooperation would enhance Africa's smallholders’ enterprise development.
Development and Initial Validation of the Alcohol Expectancy Task
Authors: Kuntsche Emmanuel , Kuntsche Sandra 
Published: June 2017

BackgroundAlthough studies have shown that alcohol expectancies are prominent predictors of alcohol initiation and subsequent drinking levels, the questionnaires used to assess these expectancies among young adolescents have been criticized as being time‐intensive, biased, and inappropriate.MethodsIn response, we developed the Alcohol Expectancy Task (AET), in which 8 scenarios featuring adults in everyday situations and in different emotional states, accompanied by photographs of a range of beverages (4 alcoholic, 8 nonalcoholic), are displayed on a tablet screen, and participants are then asked to tap on the beverage they think the given person had been drinking.ResultsIn a first study among 184 adults (75.1% women; mean age = 37.8, SD = 12.2), results from a repeated‐measures analysis of variance revealed a strong correspondence between the emotions depicted in the scenarios and how the participants interpreted them. In a second study, this time among 283 third and fourth graders (50.2% girls; mean age = 10.6, SD = 0.69), a confirmatory factor analysis confirmed the 4‐factor structure of the AET. The results from a logistic regression analysis showed that the more often young adolescents assigned alcohol to the adults in an arousal‐positive mood than to those in a sedation‐negative mood, the more likely they were to have already consumed alcohol more than twice. Questionnaire‐assessed expectancies were unrelated to adolescents’ drinking and did not affect the associations of the AET.ConclusionsThe AET has the advantage of being time‐efficient and convenient and could overcome certain limitations associated with questionnaire‐based assessments of alcohol expectancy.
APOBEC3G is increasingly expressed on the human uterine cervical intraepithelial neoplasia along with disease progression
Authors: Iizuka Takashi , Wakae Kousho , Nakamura Mitsuhiro , Kitamura Koichi , Ono Masanori , Fujiwara Hiroshi , Muramatsu Masamichi 
Published: June 2017

ProblemAPOBEC3G (A3G) is a cytidine deaminase that exhibits antiviral activity by introducing C‐to‐T hypermutation in viral DNA. We recently observed the distinct presence of C‐to‐T hypermutation of human papillomavirus DNA in uterine cervical intraepithelial neoplasia (CIN), suggesting the possible involvement of A3G in the mutation‐inducing process. Consequently, we investigated the association of A3G expression with CIN progression in this study.Method of studyPatients who had undergone cervical conization due to CIN1 (n=11), CIN2 (n=9), CIN3 (n=12), and micro‐invasive squamous cell carcinoma (n=2) were included. The expression profiles of A3G and p16 proteins in cervical lesions and A3G‐positive immune cells around the lesions were examined by immunohistochemistry.ResultsImmunoreactive A3G protein was detected in the CIN and squamous cell carcinoma lesions. Its expression intensity and positive areas were increased and spread in accordance with the progression of CIN, respectively. The co‐expression of p16 was observed on the A3G‐positive atypical cells. The numbers of A3G‐positive immune cells in CIN3 lesions were significantly higher than those of CIN1‐2 lesions.ConclusionThese findings indicate that A3G is associated with CIN, suggesting its important roles in human papillomavirus‐induced pathophysiological processes such as CIN progression and viral elimination.
Digging into My Past: Archaeology and Humanism in the Canadian Arctic
Authors: Searles Edmund 
Published: June 2017

SUMMARYThe legal battles ensuing from the discovery of the “Kennewick Man” brought mass media attention to a longstanding divide between the science of archaeology and contemporary indigenous peoples. In this essay, I reflect on this divide as experienced from the perspective of a student of archaeology who later became a cultural anthropologist specializing in the anthropology of Inuit/settler relations in Nunavut. Building on the concept of community‐oriented approaches to archaeology, I examine how a humanistic approach to archaeological data can further unite indigenous peoples and professional archaeology.
Technical Performance and Clinical Effectiveness of Drop Type With Adjustable Concentrator‐Cell Free and Concentrated Ascites Reinfusion Therapy
Authors: Yamada Yosuke , Harada Makoto , Yamaguchi Akinori , Kobayashi Yasuko , Chino Takashi , Minowa Takashi , Kosuge Takashi , Tsukada Wataru , Hashimoto Koji , Kamijo Yuji 
Published: June 2017

AbstractCell‐free and concentrated ascites reinfusion therapy (CART) is a very useful treatment method for refractory ascites but is difficult for many hospitals to employ due to its need for specialized equipment. We have therefore developed drop‐type with adjustable concentrator CART (DC‐CART) that uses a drop‐type filtration mechanism and requires only a simple pump and pressure monitor for its concentration process. Easy adjustment of ascites concentration is possible through a recirculation loop, and filter membrane washing is aided by DC‐CART's external pressure‐type filtration to enable the processing of any quality or quantity of ascites. Moreover, the absence of a roller pump before filtration avoids inflammatory substance release from compressed cells. A total of 268 sessions of DC‐CART using ascites from 98 patients were performed with good clinical results at our hospitals between January 2012 and June 2016. This report presents the detailed methods of DC‐CART and summarizes its clinical effectiveness using patient ascites and blood data obtained from 59 sessions between March 2015 and February 2016. This novel technique successfully processed refractory ascites in numerous diseases with no serious adverse events. DC‐CART could concentrate large amounts of ascites (from median weight: 4900 g [max: 20 200 g] to median weight: 695 g; median concentration ratio: 7.4), and a high amount of protein (median weight: 73 g [max: 294 g]) could be reinfused. Serum albumin levels were significantly increased (P = 0.010) and kidney function and systemic hemodynamics were well maintained in treated subjects. Additional concentration of ascites and adjustment of ascites volume were easily performed by recirculation (from median weight: 615 g to median weight: 360 g; median concentration ratio: 1.5). Time was needed during DC‐CART for filter membrane cleaning, especially for viscous ascites. Overall, DC‐CART represents a safe and useful treatment method for various forms of refractory ascites that can be performed at a wide range of health care institutions.
Hypothalamic hamartoma: Neuropathology and epileptogenesis
Authors: Kerrigan John F. , Parsons Angela , Tsang Candy , Simeone Kristina , Coons Stephen , Wu Jie 
Published: June 2017

SummaryHypothalamic hamartomas (HHs) are congenital malformations of the ventral hypothalamus resulting in treatment‐resistant epilepsy and are intrinsically epileptogenic for the gelastic seizures that are the hallmark symptom of this disorder. This paper reviews the neuropathologic features ofHHs associated with epilepsy, with an emphasis on characterizing neuron phenotypes and an ultimate goal of understanding the cellular model of ictogenesis occurring locally within this tissue. We also present previously unpublished findings on Golgi staining ofHH. The microarchitecture ofHHis relatively simple, with nodular clusters of neurons that vary in size and abundance with poorly defined boundaries. Approximately 80–90% ofHHneurons have an interneuron‐like phenotype with small, round soma and short, unbranched processes that lack spines. These neurons express glutamic acid decarboxylase and likely utilize γ‐aminobutyric acid (GABA) as their primary neurotransmitter. They have intrinsic membrane properties that lead to spontaneous pacemaker‐like firing activity. The remainingHHneurons are large cells with pleomorphic, often pyramidal, soma and dendrites that are more likely to be branched and have spines. These neurons appear to be excitatory, projection‐type neurons, and have the functionally immature behavior of depolarizing and firing in response toGABAligands. We hypothesize that the irregular neuronal clusters are the functional unit for ictogenesis. Further research to define and characterize these local networks is required to fully understand the cellular mechanisms responsible for gelastic seizures.
Medical management and antiepileptic drugs in hypothalamic hamartoma
Authors: Helen Cross J. , Spoudeas Helen 
Published: June 2017

SummaryHypothalamic hamartoma may present with epilepsy, specifically gelastic or dacrystic seizures, or endocrine dysfunction, commonly precocious puberty. The epilepsy in many patients is drug resistant, and has a high association with progressive cognitive, learning and behavioral difficulty. Medical treatment of seizures remains problematic, with many resistant to drug treatment. Surgical resection, or disconnection of the hamartoma provides the optimal chance of seizure control but with a relatively high risk of endocrine dysfunction, the result of interference with the hypothalamic‐pituitary axis in many. Careful assessment and monitoring by specialist centers with discussion of optimal intervention is required for individual cases.
Cognition in epilepsy patients with hypothalamic hamartomas
Authors: Wagner Kathrin , Wethe Jennifer V. , Schulze‐Bonhage Andreas , Trippel Michael , Rekate Harold , Prigatano George P. , Kerrigan John F. 
Published: June 2017

SummaryMany patients with epilepsy caused by hypothalamic hamartomas (HHs) have cognitive impairments during the course of the disease or following neurosurgical treatment. The purpose of this study was to assess cognitive function in these patients, as well as factors influencing preoperative cognitive performance and cognitive outcome after neurosurgical treatment. Using the two largest and most detailed neuropsychology datasets on HH and epilepsy from two centers, we retrospectively report on cognitive functions in 48 patients with structural epilepsy due to HH (mean age ± standard deviation [SD] 20 ± 12 years, range 5–53 years, median 16 years; disease duration mean 17 ± 11 years). Intelligence, verbal learning and recall, and speed and executive functions (processing speed and cognitive flexibility) were assessed before and on average 19 (±11) months after surgery (interstitial radiosurgery: N = 22; neurosurgical resection/disconnection: N = 26). Prior to neurosurgical treatment, 52% of patients showed impaired executive and 62% showed reduced verbal memory functions. A trend for a detrimental effect of higher drug load on cognitive functioning was found. After neurosurgical treatment, intellectual functions for the entire cohort tended to increase. This correlated with improved seizure frequency and decreased number of antiepileptic drugs (AEDs). However, postoperative outcomes for individual patients were highly variable, with significant deteriorations in 17% (processing speed) to 34% (cognitive flexibility and verbal learning), and performance increases in 17% (intellectual functioning) up to 39% (processing speed) of the patients. Higher levels of presurgical performance were significant predictors of cognitive decline after surgery. These results are highly relevant for patient consultation and may help with therapeutic decisions.
Gamma Knife radiosurgery for hypothalamic hamartoma preserves endocrine functions
Authors: Castinetti Frederic , Brue Thierry , Morange Isabelle , Carron Romain , Régis Jean 
Published: June 2017

SummaryGamma Knife radiosurgery (GK) is an effective treatment for hypothalamic hamartoma. No precise data are available on the risk of endocrine side effects of this treatment. In this study, 34 patients with hypothalamic hamartoma (HH) were followed prospectively at the Department of Endocrinology, La Timone Hospital, Marseille, France, for a mean follow‐up of >2 years (mean ± standard deviation [SD] 3.6 ± 2 years). Initial pre‐ and post‐GK radiosurgery evaluations were performed, including weight, body mass index (BMI), and a complete endocrinological workup. At diagnosis, eight patients presented with central precocious puberty at a mean age of 5.4 ± 2.4 years. At the time of GK (mean age 18.2 ± 11.1 years), two patients previously treated with surgery presented with luteinizing hormone/follicle‐stimulating hormone (LH/FSH) deficiency. After GK, only one patient presented with a new thyrotropin‐stimulating hormone (TSH) deficiency, 2 years after the procedure. The other pituitary axes remained normal in all but two patients (who had LH/FSH deficiency prior to GK). There was no significant difference between pre‐ and post‐GK mean BMI (26.9 vs. 25.1 kg/m2, p = 0.59). To conclude, in this group of 34 patients, GK did not induce major endocrinologic side effects reported with all the other surgical techniques in the literature. It is, thus, a safe and effective procedure in the treatment of hypothalamic hamartoma.
Public Input Provision in Asymmetric Regions with Labor Market Imperfections
Authors: Gillet Holger , Pauser Johannes 
Published: June 2017

Abstract
This paper examines efficiency in public input provision in two large regions with labor market imperfections. Because employment and pecuniary externalities are associated with public input provision, the provision level exceeds the optimal amount under the presence of wage rigidities in the capital-exporting jurisdiction if only head taxes are used to finance government expenditures. Efficiency in public input provision will remain ambiguous in the capital-importing jurisdiction unless a specific functional form is assumed for the production technology. The constrained efficient provision with public inputs can be restored with an additional tax (subsidy) on capital that is used to strategically influence the interest rate on the common capital market and to increase employment by attracting foreign capital.