bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Green Tea Supplementation on Anthropometric Indices and Inflammatory Cytokines in Women with Polycystic Ovary Syndrome
Authors: Mombaini Esmat , Jafarirad Sima , Husain Durdana , Haghighizadeh Mohammad Hossein , Padfar Parivash 
Published: February 2017

The present study aimed to determine the effect of a green tea supplement on anthropometric indices and inflammatory factors in women with polycystic ovary syndrome (PCOS). In this randomized clinical trial, 45 women with PCOS were randomly allocated into two groups receiving green tea tablets or placebo. The period of intervention was 45 days. The serum levels of interleukin 6, high‐sensitivity C‐reactive protein, and tumor necrosis factor α were measured before and after intervention period using the related kits. Anthropometric indices also were measured. The mean of body mass index, weight, waist circumference, and body fat percentage in the green tea group were reduced significantly. However, no significant difference was observed between the two groups. Also, there was no significant effect on the levels of inflammatory factors. The present results suggest that daily consumption of green tea tablets did not cause any effect on inflammation biomarkers in PCOS women. However, it may be effective as a complementary treatment for weight control in these women. Copyright © 2017 John Wiley & Sons, Ltd.
ANCIENT MAYA SETTLEMENT, INTERACTION SPHERES, AND GEOPOLITICS IN SOUTH-CENTRAL QUINTANA ROO, MEXICO
Authors: Villamil Laura P. , Sherman R. Jason 
Published: February 2017

AbstractThis paper presents the results of investigations at the ancient Maya site of Margarita in south-central Quintana Roo, Mexico, and relates them to documented patterns at neighboring centers. Following initial settlement of the region in the Middle Preclassic, settlement hierarchies topped by large centers with monumental architecture, carved monuments, and associations with sites to the south emerged in the Late Preclassic to Early Classic periods. In the Late Classic, several primary centers declined and there was a proliferation of affluent urban populations—evidenced by construction of elaborate residential groups—at smaller centers like Margarita. Long-distance cultural affiliations shifted as well, with ceramic and architectural links to western and northern Yucatán becoming pronounced. Many settlements were abandoned in the Terminal Classic, but there is also evidence of the formation of “post-collapse” communities at Margarita and other neighboring sites during the same period.
Surgical Treatment of Acquired Atresia of the External Auditory Ear Canal
Authors: Droessaert Valerie , Vanspauwen Robby , Offeciers Erwin , Zarowski Andrzej , Dinther Joost , Somers Thomas 
Published: February 2017

Introduction Acquired atresia of the external auditory canal is characterized by the formation of fibrous tissue in the medial part. The causes include chronic otitis externa, perforated chronic otitis media, postoperative or idiopathic healing problems. Acquired atresia presents with hearing loss and can be associated with otorrhea.
Objective We analyzed the results of surgery after six months and two years by checking (1) pre- and postoperative hearing thresholds; (2) presence of otorrhea; and (3) whether a dry and patent ear canal is achieved.
Methods We conducted this retrospective study at a tertiary referral center. In total, 27 ears underwent treatment with resection of the fibrotic plug followed by transplantation of a split-thickness skin graft covering the bare bone and tympanic membrane. When necessary, we combined this with a myringoplasty and a (meato-) canalplasty.
Results Otorrhea was present in 59.3% of the patients initially and in 14.8% at six months and 11% at two years postoperative. A dry and patent ear canal was obtained in 55.6% after six months and in 89% of the patients after two years (n = 27). The pure tone average before surgery was 39.1 dBHL (SD = 20 dBHL), at six months 31.4 dBHL (SD = 16.4 dBHL), and at 24 months postop 30.9 dBHL (SD = 17.1 dBHL). We observed a statistically significant improvement of hearing in 63% of the patients at six months (p = 0.005) and in 65% after two years (p = 0.022).
Conclusions Treatment of acquired atresia remains a challenge. Using the appropriate surgical technique, including skin-grafting and regular postoperative check-up, rendered excellent results regarding otorrhea and a moderate improvement of hearing was achieved in 65% of the patients after two years.
P300: Waves Identification with and without Subtraction of Traces
Authors: Romero Ana , Reis Ana , Oliveira Anna , Oliveira Simões Humberto , Oliveira Junqueira Cinthia , Frizzo Ana 
Published: February 2017

Introduction The P300 test requires well-defined and unique criteria, in addition to training for the examiners, for a uniform analysis of studies and to avoid variations and errors in the interpretation of measurement results.
Objectives The objective of this study is to verify whether there are differences in P300 with and without subtraction of traces of standard and nonstandard stimuli.
Method We conducted this study in collaboration with two research electrophysiology laboratories. From Laboratory 1, we selected 40 tests of subjects between 7–44 years, from Laboratory 2, we selected 83 tests of subjects between 18–44 years. We first performed the identification with the nonstandard stimuli; then, we subtracted the nonstandard stimuli from the standard stimuli. The examiners identified the waves, performing a descriptive and comparative analysis of traces with and without subtraction.
Results After a comparative analysis of the traces with and without subtraction, there was no significant difference when compared with analysis of traces in both laboratories, within the conditions, of right ears (p = 0.13 and 0.28 for differences between latency and amplitude measurements) and left ears (p = 0.15 and 0.09 for differences between latency and amplitude measurements) from Laboratory 1. As for Laboratory 2, when investigating both ears, results did not identify significant differences (p = 0.098 and 0.28 for differences between latency and amplitude measurements).
Conclusion There was no difference verified in traces with and without subtraction. We suggest the identification of this potential performed through nonstandard stimuli.
Management of Breast Cancer during Pregnancy: Are We Compliant with Current Guidelines?
Authors: Shlensky Victoria , Hallmeyer Sigrun , Juarez Lourdes , Parilla Barbara 
Published: February 2017

Introduction The purpose of this study was to evaluate the management of patients with breast cancer in pregnancy treated at the Advocate Health Care, to determine whether these patients were treated according to guidelines for pregnant patients, which aim to maximize both fetal and maternal outcomes.
Methods A retrospective chart review was performed at the Advocate Lutheran General Hospital, Christ Medical Center, and Illinois Masonic Medical Center from 2002 to 2012 on patients diagnosed with breast cancer during pregnancy using ICD-9 (International Classification of Diseases - 9th version) codes.
Results Eleven patients between 12 and 37 weeks' gestation matched the search criteria. One patient terminated the pregnancy. Patients in our study were treated appropriately according to guidelines with the following exceptions. Trastuzumab was used in one patient during pregnancy which likely caused the oligohydramnios resulting in an induction of labor at 33 weeks. Three patients were delivered preterm between 34 and 36 weeks without an obstetric indication. Two patients underwent sentinel node biopsy.
Conclusion The diagnosis of breast cancer in pregnancy is an infrequent but devastating diagnosis that is likely to increase. Although sentinel lymph node biopsy is not generally recommended in pregnancy, this may be an outdated guideline as using a low-dose lymphoscintigraphic technique appears to be safe in pregnancy.
Evolution of N/O abundance ratios and ionization parameters from z ∼ 0 to 2 investigated by the direct temperature method
Authors: Kojima Takashi , Ouchi Masami , Nakajima Kimihiko , Shibuya Takatoshi , Harikane Yuichi , Ono Yoshiaki 
Published: February 2017

Abstract
We present N/O abundance ratios, ionization parameters qion, and oxygen abundances O/H for a total of 41 galaxies (11 individual galaxies and a 30-galaxy stack) including Lyα emitters and Lyman break galaxies at z ∼ 2, and investigate galaxy evolution from z ∼ 0 to 2 in conjunction with 208529 local galaxies from the Sloan Digital Sky Survey (SDSS) and nine green pea galaxies (GPs). In contrast with most of the recent studies, we obtain the N/O ratio, qion, and O/H measurements by direct Te methods using [O iii] λ4363 and O iii] λ1665 lines. Based on these reliable measurements, we find that there are z ∼ 2 galaxies with excesses of N/O falling beyond the N/O–O/H relation of the local galaxies while the majority of the z ∼ 2 galaxies have N/O ratios that are nearly comparable with those of z ∼ 0 galaxies in the N/O–stellar mass relation. Our galaxies place the upper limit of the N/O ratio log(N/O) ≤ −1.26 on average, suggesting that the N/O ratio evolves, if at all, by &lt;0.17 dex. Obtaining the reliable measurements free from the N/O–qion–O/H degeneracies, we demonstrate, for the first time, that z ∼ 2 galaxies with offsets in the Baldwin–Phillips–Terlevich (BPT) diagram show (1) only an N/O excess, (2) only a qion excess, or (3) both N/O and qion excesses. We argue that the BPT offsets at z ∼ 2 are not made by one of the (1)–(3) galaxy populations alone, but a composite of (1)–(3) populations. We confirm that these (1)–(3) populations also exist at z ∼ 0, such as GPs and SDSS low-mass and high-SFR galaxies (LMHSs).
The Associated Factors and Clinical Features of Neuropathic Pain After Brachial Plexus Injuries
Authors: Zhou Yingjie , Liu Peixi , Rui Jing , Zhao Xin , Lao Jie 
Published: February 2017

Introduction:
Neuropathic pain in patients with brachial plexus injuries brings complicated obstacles to the treatment and recovery for both surgeons and patients.

Objectives:
The clinical features of neuropathic pain, including pain intensity, type and time phase, need to be investigated. Moreover, possible associated factors need to be explored.

Methods:
A cross-sectional study containing 77 participants was conducted. Their baseline information and injury-related conditions were collected. The Present Pain Index evaluated by the Visual Analog Scale, self-reports using the specific pain questionnaires were used for screening and estimating the patients’ pain. T test, χ2 test, Logistic Regression, and correlation coefficient were used when conducting the statistical analyses.

Results:
The occurrence rate of neuropathic pain in our study was 54.5%. Paresthesia/dysesthesia had the highest average score in our population. Among potential associated factors, smoking (P=0.001), regular alcohol drinking (P=0.001), total brachial plexus injuries (P=0.01), and avulsions (P=0.019) were related to the development of neuropathic pain. Patients with neuropathic pain experienced significantly poorer function of the upper limbs measured by the Disabilities of Arm, Hand and Shoulder questionnaire (P<0.01). There was a significant positive correlation between the function of the upper limbs and pain intensity (r=0.60, P<0.001).

Discussion:
Though the pain type and time phase manifested differently across patients, paresthesia/dysesthesia occurred most commonly. Patients were more likely to develop neuropathic pain if they had total brachial plexus injuries, avulsion and bad life habits. Moreover, the function of the upper limbs was affected by pain.
Estrogen- and Progesterone-Induced Variation in Corneal Parameters According to Hormonal Status
Authors: Bahadir Kilavuzoglu Ayse Ebru , Cosar Cemile Banu , Bildirici Ibrahim , Cetin Omer , Ozbasli Esra 
Published: February 2017

Objectives:
To determine the effects of estrogen and progesterone on corneal thickness, curvature, and biomechanics in healthy corneas according to hormonal status.

Methods:
The study included four groups of females: group A (menstruating, not pregnant, not lactating, and not menopausal; n=100), group B (pregnant; n=50), group C (lactating; n=50), and group D (menopausal; n=50). Group A was subdivided according to age, as subgroup A15–25 (age 15–25 years) and subgroup A>25 (age >25 years). Blood estradiol and progesterone levels were measured in each participant. All the participants underwent a full ophthalmologic examination, including corneal thickness and corneal topography measurement, and evaluation of corneal biomechanical properties.

Results:
The corneal resistance factor and anterior corneal flat keratometry values were significantly higher in group D (P=0.040 and P=0.026, respectively) than in the other three groups. Posterior corneal steep keratometry values were significantly higher in subgroup A>25 during the preovulatory phase than ovulatory and postovulatory phases (P=0.012). In group B, there was a significant negative correlation between gestational week and intraocular pressure (IOP) (r=−0.322, P=0.024). Corneal volume was significantly higher during the early postpartum period than the late postpartum period in group C (P=0.028). Intraocular pressure, Goldman-correlated IOP, and corneal-compensated IOP differed significantly between the groups (P<0.05).

Conclusions:
Blood levels of estrogen and progesterone were associated with variations in IOP, but estrogen and progesterone did not have a consistent effect on topographic parameters or biomechanical properties in healthy corneas.
Not moving: the fundamental but neglected motor function
Authors: Noorani Imran , Carpenter R. H. S. 
Published: February 2017

The function of the motor system in preventing rather than initiating movement is often overlooked. Not only are its highest levels predominantly, and tonically, inhibitory, but in general behaviour it is often intermittent, characterized by relatively short periods of activity separated by longer periods of stillness: for most of the time we are not moving, but stationary. Furthermore, these periods of immobility are not a matter of inhibition and relaxation, but require us to expend almost as much energy as when we move, and they make just as many demands on the central nervous system in controlling their performance. The mechanisms that stop movement and maintain immobility have been a greatly neglected area of the study of the brain. This paper introduces the topics to be examined in this special issue ofPhilosophical Transactions, discussing the various types of stopping and stillness, the problems that they impose on the motor system, the kinds of neural mechanism that underlie them and how they can go wrong.This article is part of the themed issue ‘Movement suppression: brain mechanisms for stopping and stillness’.
Behavioural and computational varieties of response inhibition in eye movements
Authors: Cutsuridis Vassilis 
Published: February 2017

Response inhibition is the ability to override a planned or an already initiated response. It is the hallmark of executive control as its deficits favour impulsive behaviours, which may be detrimental to an individual's life. This article reviews behavioural and computational guises of response inhibition. It focuses only on inhibition of oculomotor responses. It first reviews behavioural paradigms of response inhibition in eye movement research, namely the countermanding and antisaccade paradigms, both proven to be useful tools for the study of response inhibition in cognitive neuroscience and psychopathology. Then, it briefly reviews the neural mechanisms of response inhibition in these two behavioural paradigms. Computational models that embody a hypothesis and/or a theory of mechanisms underlying performance in both behavioural paradigms as well as provide a critical analysis of strengths and weaknesses of these models are discussed. All models assume the race of decision processes. The decision process in each paradigm that wins the race depends on different mechanisms. It has been shown that response latency is a stochastic process and has been proven to be an important measure of the cognitive control processes involved in response stopping in healthy and patient groups. Then, the inhibitory deficits in different brain diseases are reviewed, including schizophrenia and obsessive-compulsive disorder. Finally, new directions are suggested to improve the performance of models of response inhibition by drawing inspiration from successes of models in other domains.
This article is part of the themed issue ‘Movement suppression: brain mechanisms for stopping and stillness’.
A global perspective on bioinformatics training needs
Authors: Brazas Michelle D. , Brooksbank Cath , Jimenez Rafael C. , Blackford Sarah , Palagi Patricia M , De Las Rivas Javier , Ouellette B.F. Francis , Kumuthini Judit , Korpelainen Eija , Lewitter Fran , van Gelder Celia W.G. , Mulder Nicola , Corpas Manuel , Schneider Maria Victoria , Tan Tin Wee , Clements Dave , Davies Angela , Attwood Teresa K. 
Published: February 2017

AbstractIn the last decade, life-science research has become increasingly data-intensive and computational. Nevertheless, basic bioinformatics and data stewardship are still only rarely taught in life-science degree programmes, creating a widening skills gap that spans educational levels and career roles. To better understand this situation, we ran surveys to determine how the skills dearth is affecting the need for bioinformatics training worldwide. Perhaps unsurprisingly, we found that respondents wanted more short courses to help boost their expertise and confidence in data analysis and interpretation. However, it was evident that most respondents appreciated their need for training only after designing their experiments and collecting their data. This is clearly rather late in the research workflow, and suboptimal from a training perspective, as skills acquired to address a specific need at a particular time are seldom retained, engendering a cycle of low confidence in trainees. To ensure that such skill gaps do not continue to create barriers to the progress of research, we argue that universities should strive to bring their life-science curricula into the digital-data era. Meanwhile, the demand for point-of-need training in bioinformatics and data stewardship will grow. While this situation persists, international groups like GOBLET are increasing their efforts to enlarge the community of trainers and quench the global thirst for bioinformatics training.
Social media activity in a festival context: temporal and content analysis
Authors: MacKay Kelly , Barbe Danielle , Van Winkle Christine M. , Halpenny Elizabeth 
Published: February 2017

Purpose
This study explores the multi-phasic experience of festivals to understand the nature, purpose and degree of social media (SM) use before, during and after festival occurrence and how this may inform better engagement of attendees.

Design/methodology/approach
A census of tweets and posts from four festivals’ Twitter handles and Facebook accounts were coded and analyzed across three time points: one week prior, during and one week after the festival. They were coded on nature (e.g. conversational, promotional, informational), purpose (e.g. information-seeking, friendship/relationship) and presence of links, photos, etc. Tests for platform influences on usage were conducted.

Findings
In total, 1,169 tweets and 483 posts were captured. Two-thirds of SM activity occurred during the festivals, one-third pre-festival and minimal activity post festival. Temporal analyses found that while the purpose and nature of the message content varied across festival time points, this was often dependent on SM platform.

Research limitations/implications
Festivals are not taking advantage of the multi-phase experience model and the utility of SM to maintain contact and encourage visitors to continue processing their experience after the festival. This lost opportunity has implications for re-patronizing behaviour and sponsor relationships.

Originality value
Leung et al. (2013a) call for sector specific research to elucidate SM use in tourism. Festivals provide a unique environment of co-created experience. Findings suggest differential usage of SM across festival time frames and platforms that can be used to guide festival organizations’ SM communication to better engage its patrons.
Can smart homes extend people with Alzheimer’s disease stay at home?
Authors: Brunete González Alberto , Selmes Micheline , Selmes Jacques 
Published: February 2017

Purpose
The purpose of this paper is to analyse the needs of people with Alzheimer’s disease and their caregivers in terms of information and communications technology (ICT) and home automation, and how to foster the use of smart devices in their homes and also, to determine whether the use of ICT can extend people with Alzheimer’s disease stay at home in the first stages of the illness, while facilitating their caregivers’ tasks.

Design/methodology/approach
Groups of caregivers, ICT researchers and Alzheimer’s disease experts were gathered to discuss the utility of several solutions. Sessions were grouped into four topics: safety, leisure, activities of daily living and friendly atmosphere. In total, 23 ICT-based solutions to improve life at home of people with Alzheimer’s disease were analysed and grouped under “no interest”, “some interest” and “very interesting”. Caregivers rated these solutions and suggested improvements to them.

Findings
In total, 18 out of 23 proposals were considered “very interesting”, meaning that caregivers considered that they could truly improve the lives of people with Alzheimer’s disease. Caregivers also suggested how to progressively introduce these technical solutions into their homes.

Originality/value
ICT and home automation advances could be very useful if used conveniently. Caregivers consider that smart homes can help people with Alzheimer’s disease in the security, leisure and daily tasks fields, increasing the time they can live alone in their own homes.
Equity incentive and risk taking: evidence from China
Authors: Wang Dong , Wu Desheng 
Published: February 2017

Purpose
China has formally implemented equity incentive for more than 10 years; thus, a considerable number of equity incentive programs has entered the exercise period. This means that it is time to conduct a comprehensive analysis of the incentive effects of equity incentive throughout the whole implementation phase. The purpose of this paper is to examine the relationship between equity incentive, enterprise’s risk taking and risk decisions in China.

Design/methodology/approach
Using sensitivity of executives’ wealth and stock price (Delta) to measure the alignment effect and using sensitivity of executives’ wealth and stock return volatility (Vega) to measure the risk-taking effect, this paper aims to empirically test the relation of equity incentive and enterprise’s risk taking and risk decisions.

Findings
The authors find that Vega is positively related to risk taking; however, this improvement was mainly reflected in the private enterprises rather than state-owned enterprises. In terms of corporate policy choice, the authors find that Vega is positively related to firm focus and leverage. But, they have not found that Vega can promote R&D investment.

Originality/value
Existing studies have mostly concerned about the executives’ opportunistic behavior; however, analyses of the positive effect of equity incentive are limited. The authors use a combination of risk-taking incentives and alignment incentives to test the relationship between equity incentive and risk taking.