bluuebunny/crossref_metadata_2025_split huggingface dataset:
PAWS1 controls cytoskeletal dynamics and cell migration through association with the SH3 adaptor CD2AP
Authors: Cummins Timothy D. , Wu Kevin Z. L. , Bozatzi Polyxeni , Dingwell Kevin S. , Macartney Thomas J. , Wood Nicola T. , Varghese Joby , Gourlay Robert , Campbell David G. , Prescott Alan , Griffis Eric , Smith James C. , Sapkota Gopal P. 
Published: January 2018

ABSTRACT
Our previous studies of PAWS1 (protein associated with SMAD1; also known as FAM83G) have suggested that this molecule has roles beyond BMP signalling. To investigate these roles, we have used CRISPR/Cas9 to generate PAWS1-knockout U2OS osteosarcoma cells. Here, we show that PAWS1 plays a role in the regulation of the cytoskeletal machinery, including actin and focal adhesion dynamics, and cell migration. Confocal microscopy and live cell imaging of actin in U2OS cells indicate that PAWS1 is also involved in cytoskeletal dynamics and organization. Loss of PAWS1 causes severe defects in F-actin organization and distribution as well as in lamellipodial organization, resulting in impaired cell migration. PAWS1 interacts in a dynamic fashion with the actin/cytoskeletal regulator CD2AP at lamellae, suggesting that its association with CD2AP controls actin organization and cellular migration. Genetic ablation of CD2AP from U2OS cells instigates actin and cell migration defects reminiscent of those seen in PAWS1-knockout cells.
This article has an associated First Person interview with the first authors of the paper.
Organisational structures and personal spiritual belief
Authors: Keighley Tom 
Published: January 2018

This paper is based on the author's experience of working with NHS chaplains who may or may not have worked in palliative care areas. ‘A Framework for Spiritual, Faith and Related Pastoral Care’ (1995), developed in response to ‘The Patient's Charter’ (Department of Health (DoH) 1991) provides much of the material that underpins this paper. While certain material within this paper relates directly to palliative care, the main thrust concerns the principles that sustain good organisational practice when trying to meet the increasingly diverse spiritual needs of patients. The Framework paper on which this is based recognises the major changes that have occurred in the nature of care delivery and, therefore, the way in which traditional approaches to chaplaincy have been modified. This paper outlines a number of strategies that can be pursued to facilitate this change and concludes with some specific observations about the significance of change for the palliative care arena.
Teaching spiritual care to nurses: an alternative approach
Authors: Bradshaw Ann 
Published: January 2018

This paper presents an approach to teaching spiritual care that is underpinned by a traditional philosophy of care as agape. In this approach spiritual care is considered a fundamental character of care, not a self-conscious addition. The caring function of the nurse is qualitatively differentiated from that of the religious minister, whose role is considered to be currently underestimated. From this perspective, teaching spiritual care to nurses is not so much achieved through theoretical or experiential analysis and reflection, but by following an established moral pattern; it is not taught so much as caught. It is argued that this traditional approach to spiritual care provides an alternative to current educational ideologies in nursing, and reflects patients' and nurses' own attitudes to – and expectations of – the spiritual dimension of care.
For whenever I am weak, I am strong…
Authors: Cornette Katrien 
Published: January 2018

A large scale empirical study concerning spiritual pain at the end of life was set up by a multi-disciplinary group of palliative care specialists in Flanders, Belgium. All Flemish speaking palliative care health workers were sent a questionnaire concerning spiritual/religious needs, care and growth. This paper focuses on issues relating to spiritual needs and growth of the caregivers. Although respondents considered the ability to identify personal spiritual needs as an important criterion for offering good spiritual care, in-depth analysis suggests a considerable gap between theoretical insight and daily practice. Findings advocate greater awareness and assertiveness among caregivers regarding their own spiritual experiences. A structural implementation of supervision to address the hidden spiritual agenda of the palliative team may need to pre-empt systems that teach how to respond more adequately to patients' spiritual needs.
The concepts of truth telling and informed consent
Authors: Gent Carolyn 
Published: January 2018

In the palliative care setting, nurses are regularly faced with the dilemma of what to tell their patients about the progress of their illness, treatment and their prognosis. This dilemma is not always handled in the best way and there are many difficulties for the nurse. This article examines the legal aspects of informed consent and highlights the dilemmas faced by nurses working in the palliative care field of nursing. This is an area which will remain controversial until open and clear guidance is given to carers on their roles and responsibilities. The objective of this article is to highlight the areas of difficulty where lack of clarity exist in order to provoke discussion on how these problems can be resolved.
Third-generation pure alumina and alumina matrix composites in total hip arthroplasty
Authors: Hannouche Didier , Zingg Matthieu , Miozzari Hermes , Nizard Remy , Lübbeke Anne 
Published: January 2018

Wear, corrosion and periprosthetic osteolysis are important causes of failure in joint arthroplasty, especially in young patients. Ceramic bearings, developed 40 years ago, are an increasingly popular choice in hip arthroplasty. New manufacturing procedures have increased the strength and reliability of ceramic materials and reduced the risk of complications. In recent decades, ceramics made of pure alumina have continuously improved, resulting in a surgical-grade material that fulfills clinical requirements. Despite the track record of safety and long-term results, third-generation pure alumina ceramics are being replaced in clinical practice by alumina matrix composites, which are composed of alumina and zirconium. In this review, the characteristics of both materials are discussed, and the long-term results with third-generation alumina-on-alumina bearings and the associated complications are compared with those of other available ceramics.Cite this article: EFORT Open Rev 2018;3:7-14. DOI: 10.1302/2058-5241.3.170034
Performance of watermelon (Citrullus lanatus L.) in response to organic and NPK fertilizers
Authors: Eifediyi Ehiokhilen Kevin , Remison Samson Uduzei , Ahamefule Henry Emeka , Azeez Kameel Olubukola , Fesobi Phillip Olumide 
Published: January 2018

AbstractThe soil of North-Central Nigeria is home to many plant products that are used as industrial raw materials, and after processing their waste are often left in drainage channels, which ultimately find their way into rivers and streams where they pollute these water bodies, and sometimes some of these materials are burnt, which further aggravates global warming. In addition, the soil of the region is characterized by low organic matter content because of annual bush burnings, which reduce the low humus content of soils. Watermelon requires a fertile soil, which is high in organic matter content, while infertile soils yield an increased production of male flowers at the expense of female flowers, which results in low fruit set. Therefore, a study was carried out at the University of Ilorin Teaching and Research Farm, Ilorin, North-Central Nigeria, during the rainy seasons of 2013 and 2014 to assess the effect of different organic materials on the growth and yield of watermelon. The factors imposed were a control, NPK fertilizer and five organic materials (neem seed cake (NSC), jatropha seed cake (JSC), poultry manure (PM), compost manure (CM), and cow dung (CD)). The experiment was a randomized complete block design (RCBD) replicated thrice. Data collected on soil physico-chemical properties were: organic matter content, soil pH, organic carbon, total N, P, K, Ca, and Mg, bulk density (BD), micro porosity (MIP), macro porosity (MAP), and saturated hydraulic conductivity (KS). Plant parameters evaluated include growth (vine length and number of leaves) and yield (number of fruits per plant, fruit weight per plant, and yield ha−1). Results indicated that the organic matter content increased after the first year’s cropping and declined at the end of the study. The amended plots showed significantly higher values (P < 0.05) with respect to most soil physical properties (MIP), (MAP), and (KS), except the BD, where the values were lower. The bulk density particularly deteriorated on soils that were not organically amended. In addition, the soil chemical properties examined increased following the first year’s cropping, and thereafter declined at the end of the second-year cropping season. The response of watermelon showed that the two years’ yield data ranged between 334 and 402 t/ha, 306 and 390 t/ha, and 38.25 and 59.20 t/ha for NPK, poultry manure, and control treatments respectively. From the results, it was observed that the organic amendments were environmentally more friendly compared to the inorganic amendment (NPK fertilizer) in terms of positive effects on soil structural properties.
Investigation of thysanoptera populations in Hungarian greenhouses
Authors: Orosz Szilvia , Éliás Dávid , Balog Emese , Tóth Ferenc 
Published: January 2018

Abstract
Studies were performed on sweet pepper and on weeds in their surroundings from 2005 to 2007 in the Jászság region, on different vegetables and ornamentals from 2015 to 2016 throughout Hungary, and on some indoor ornamental plants in Budapest and Kecskemét in 2017. These studies were carried out in greenhouses. The main objectives of this work was to clarify the consistency of Thysanoptera populations in these greenhouses and, secondly, as part of the official monitoring of Thrips palmi Karny and Thrips setosus Moulton, the study also focused on the first appearance of these pests in Hungary. An important additional aim was to determine which reservoirs were significant in the risk of Thysanoptera species transmitting tomato spotted wilt virus (TSWV). Regarding the surveys conducted, the most frequent Thysanoptera species present in large numbers during the investigation period in every greenhouse was Frankliniella occidentalis Pergande. Also, a significant amount of Echinothrips americanus Morgan was found on ornamentals in southern Hungary, whereas on indoor ornamental plants only Hercinothrips femoralis O. M. Reuter was found.
Synthesis, characterization, thermal degradation and urease inhibitory studies of the new hydrazide based Schiff base ligand 2-(2-hydroxyphenyl)-3-{[(E)-(2-hydroxyphenyl)methylidene]amino}-2,3-dihydroquinazolin-4(1H)-one
Authors: Ikram Muhammad , Rehman Sadia , Subhan Fazle , Akhtar Muhammad Nadeem , Sinnokrot Mutasem Omar 
Published: January 2018

AbstractThe novel Schiff base ligand 2-(2-hydroxyphenyl)-3-{[(E)-(2-hydroxyphenyl)methylidene]amino}-2,3-dihydroquinazolin-4(1H)-one(H-HHAQ)derived from 2-aminobenzhydrazide was synthesized and characterized by elemental analyses, ES+-MS,1H and13C{1H}-NMR, and IR studies. The characterization of the ligand was further confirmed by single crystal analysis. The Schiff base ligand was complexed with metal ions like Co(II), Ni(II), Cu(II) and Zn(II) to obtain the bis-octahedral complexes. The ligand and its metal complexes were also studied for their urease inhibitory activities. All the tested compounds show medium to moderate activities for the enzyme, whereas the copper based complex was found to be much more active against urease with an IC50=0.3 ± 0.1 μM±SEM, which is even more potent than the standard thiourea. The IC50of the cobalt complex was 43.4±1.2 μM±SEM, whereas that of the nickel complex was 294.2±5.0 μM±SEM. The ligandH-HHAQand the zinc complex were inactive against the tested enzyme.
Oscillation and Periodicity of a Second Order Impulsive Delay Differential Equation with a Piecewise Constant Argument
Authors: Oztepe Gizem S. , Karakoc Fatma , Bereketoglu Huseyin 
Published: January 2018

Abstract
This paper concerns with the existence of the solutions of a second order impulsive delay differential equation with a piecewise constant argument. Moreover, oscillation, nonoscillation and periodicity of the solutions are investigated.
Biodiversity indexes in relation to soil properties in upland fir forests (Abietetum albae)
Authors: Lasota Jarosław , Wiecheć Małgorzata , Błońska Ewa , Brożek Stanisław 
Published: January 2018

Abstract
The aim of this study was to present the relationship between soil properties and biodiversity indexes in upland fir (Abies alba) forest associations (Abietetum albae). Our study was conducted in six areas representing the growth conditions of upland fir forests and the research plots were located in the Roztoczański and Świętokrzyski National Parks as well as Przedbórz, Radomsko, Piotrków and Janów lubelski Forest District. on every plot, the topography was described, soil cores were examined and samples for laboratory analysis were taken. the following characteristics were determined for the soil samples: ph, c, n, ca, Mg, na and K content, particle size, exchangeable acidity, aluminum content and hydrolytic acidity. additionally, enzyme activity in the soil samples (urease and dehydrogenase) was measured. in each test area, the stand characteristics were measured (diameter at breast height and height), floristic characteristics were described and the biodiversity indexes (Shannon, Simpson and Margalef indexes) were calculated. Different soil types (gleysols, Brunic arenosols, gleyic Podzols and hyperdistric cambisols) were recorded for the investigated forest stands and the soils were categorized according to soil texture, c content, enzyme activity and different humus types (moder-mor, moder, moder-mull). the upland mixed coniferous forest sites were characterized by lower biodiversity indexes (2.6 shannon index; 0.72 simpson index; 4.9 Margalef index) while the upland mixed broadleaf forest sites showed higher indexes (3.3 Shannon index; 0.87 Simpson index; 9.4 Margalef index). The site index obtained for the fir stands confirmed these results.
Microencapsulation of Bioactive Compounds from Hibiscus Calyces Using Different Encapsulating Materials
Authors: Piovesana Alessandra , Noreña Caciano Pelayo Zapata 
Published: January 2018

Abstract:
Hibiscus calyces extract was microencapsulated by freeze drying and spray drying using partially hydrolyzed guar gum (PHGG), polydextrose (PD) or gum Arabic (GA) at 10 % as encapsulating agents. The retention of anthocyanins ranged from 59.8 to 64.6 % and from 66.4 to 74.3 %, and for antioxidant activity from 66.54 to 71.71 and 69.90 to 73.26 %, for spray-dried and for freeze-dried powders, respectively. The best result obtained, for the anthocyanins content, reducing capacity and ABTS, was for the powder produced by freeze drying using GA. Regarding physical powder properties, samples produced by spray drying using GA, followed by PHGG had the best results, with values of 95.80 and 95.20 %, 31.33 and 28.87 %, 17.43 and 10.96°C for solubility, hygroscopicity and Tg, respectively. Microscopy analysis also indicated that powders produced by spray drying using GA and PHGG had the best structures, showing particles of spherical shape and without agglomeration.
Influence of Freezing–Thawing Cycle on Water Dynamics of Turbot Flesh Assessed by Low-Field Nuclear Magnetic Resonance and Magnetic Resonance Imaging
Authors: Li Jiaqi , Xia Kexin , Li Yao , Tan Mingqian 
Published: January 2018

Abstract
Turbot is a valuable commercial species due to its high nutrient content. Moisture is an important indicator of meat spoilage. This study elucidated distinctive water dynamics in turbot flesh in the freezing–thawing process by nondestructive low-field nuclear magnetic resonance (LF-NMR) and magnetic resonance imaging (MRI) techniques. T
2 relaxation spectra were utilized to describe the mobility and content of different types of water. Principal component analysis (PCA) revealed a clear discrimination of various freezing–thawing cycles. T
1- and T
2-weighted MRI provided further visualization of internal information for turbot flesh. Microscopic examination clearly identified protein denaturation and structural shrinkage. Furthermore, NMR parameters and conventional physicochemical parameters of color, shear force and thiobarbituric acid-reactive substances showed good correlations. To sum up, the study revealed that LF-NMR and MRI are promising techniques to portray the relationship between the water dynamics and changes of turbot quality properties during the freezing–thawing process.
Numerical Solutions for Radiative Heat Transfer in Ferrofluid Flow due to a Rotating Disk: Tiwari and Das Model
Authors: Mustafa M. , Khan Junaid Ahmad , Hayat T. , Alsaedi A. 
Published: January 2018

Abstract
In this paper, we explore the von-Kármán infinite disk problem for the situation where ferrofluid resides in the space above the rotating disk. Furthermore, flow field is influenced by axial magnetic field. In this study, we treat water as the base fluid which consists of homogeneous suspensions of

F

e

3

O

4

${\rm{F}}{{\rm{e}}_{\rm{3}}}{{\rm{O}}_{\rm{4}}}$

ferromagnetic particles. The main motivation here is to resolve heat transfer problem in the existence of non-linear radiative heat transfer. With the aid of von-Kármán relations, the equations of fluid motion and heat transfer are changed into a set of self-similar differential equations. These equations are dealt by an implicit finite-difference method with high precision. The results reveal that wall heat transfer rate can be improved by increasing solid volume fraction of ferromagnetic particles. Drag coefficient at the disk and heat transfer rate are increased as the strength of Lorentz force is enhanced. Viscous dissipation effect has an important part in improving heart transfer process which is vital in some applications. The results demonstrate that cooling capability of magnetite–water nanofluid is much superior to the conventional coolants. An excellent correlation of present results with the previous published articles is found in the all the cases.
Impact of AC Current Density on Material Corrosion of Distribution Pipelines
Authors: Poberezhny L. , Maruschak P. , Hrytsanchuk A. , Mischuk B. , Draganovska D. , Poberezhna L. 
Published: January 2018

Abstract
Vliv střídavého indukovaného proudu na korozní rychlost oceli St3 a 17GS byl pozorován v simulovaných půdních elektrolytech typických pro Ukrajinu. Ocel St3 je citlivější na přirozené korozní napadení v půdě i na napadení vyvolané střídavým proudem. Byla stanovena nejhorší prostředí z hlediska koroze v elektrolytech obsahujících chloridy či směs chloridů se sírany.
Transnational experiences, language competences and worldviews: contrasting language policies in two recently migrated Greek families in Luxembourg
Authors: Kirsch Claudine , Gogonas Nikolaos 
Published: January 2018

AbstractAgainst the backdrop of the ongoing crisis-led migration from Southern to Northwestern Europe, the present paper reports on a case study of two families who have recently migrated from Greece to Luxembourg. Luxembourg has a trilingual education system and many pupils of migrant background face difficulties on this account. Drawing on the framework of Family Language Policy, this paper explores the language ideologies and management strategies of two families as well as factors influencing their policies. This qualitative study was based on interviews, observations, and videos recorded by one of the families. The findings show that the families have contrasting language ideologies and management strategies that are informed by their differing transnational experiences, competences and worldviews. This study can contribute to a better understanding of the ways in which migrant families use their language resources in their new country.
Analytical modeling of coupled flow and geomechanics for vertical fractured well in tight gas reservoirs
Authors: Wang Ruifei , Gao Xuhua , Song Hongqing , Shang Xinchun 
Published: January 2018

Abstract
The mathematical model of coupled flow and geomechanics for a vertical fractured well in tight gas reservoirs was established. The analytical modeling of unidirectional flow and radial flow was achieved by Laplace transforms and integral transforms. The results show that uncoupled flow would lead to an overestimate in performance of a vertical fractured well, especially in the later stage. The production rate decreases with elastic modulus because porosity and permeability decrease accordingly. Drawdown pressure should be optimized to lower the impact of coupled flow and geomechanics as a result of permeability decreasing. Production rate increases with fracture half-length significantly in the initial stage and becomes stable gradually. This study could provide a theoretical basis for effective development of tight gas reservoirs.
Comparison of the fractional power motor with cores made of various magnetic materials
Authors: Gmyrek Zbigniew , Lefik Marcin , Cavagnino Andrea , Ferraris Luca 
Published: January 2018

Abstract
The optimization of the motor cores, coupled with new core shapes as well as powering the motor at high frequency are the primary reasons for the use of new materials. The utilization of new materials, like SMC (soft magnetic composite), reduce the core loss and/or provide quasi-isotropic core’s properties in any magnetization direction. Moreover, the use of SMC materials allows for avoiding degradation of the material portions, resulting from punching process, thereby preventing the deterioration of operating parameters of the motor. The authors examine the impact of technological parameters on the properties of a new type of SMC material and analyze the possibility of its use as the core of the fractional power motor. The result of the work is an indication of the shape of the rotor core made of a new SMC material to achieve operational parameters similar to those that have a motor with a core made of laminations.
Detection of inter-turn short-circuit at start-up of induction machine based on torque analysis
Authors: Pietrowski Wojciech , Górny Konrad 
Published: January 2018

AbstractRecently, interest in new diagnostics methods in a field of induction machines was observed. Research presented in the paper shows the diagnostics of induction machine based on torque pulsation, under inter-turn short-circuit, during start-up of a machine. In the paper three numerical techniques were used: finite element analysis, signal analysis and artificial neural networks (ANN). The elaborated numerical model of faulty machine consists of field, circuit and motion equations. Voltage excited supply allowed to determine the torque waveform during start-up. The inter-turn short-circuit was treated as a galvanic connection between two points of the stator winding. The waveforms were calculated for different amounts of shorted-turns from 0 to 55. Due to the non-stationary waveforms a wavelet packet decomposition was used to perform an analysis of the torque. The obtained results of analysis were used as input vector for ANN. The response of the neural network was the number of shorted-turns in the stator winding. Special attention was paid to compare response of general regression neural network (GRNN) and multi-layer perceptron neural network (MLP). Based on the results of the research, the efficiency of the developed algorithm can be inferred.