bluuebunny/crossref_metadata_2025_split huggingface dataset:
Políticas públicas em saúde, sistema único de saúde e o papel do legislativo municipal: Um estudo sobre os projetos de Lei Ordinária na área da saúde da cidade de Curitiba no período 2008–2011
Authors: Vasconcelos Marta Chaves , Da Silva Christian Luiz , Rotta Cristiano Vieira 
Published: September 2016

As políticas públicas de saúde institucionalizadas pelo Sistema Único de Saúde (SUS) universalizaram os serviços e fortaleceram os conselhos municipais e as administrações públicas municipais para o gerenciamento deste sistema no âmbito local. Esse artigo descreve e avalia os projetos lei ordinária especificamente da área da saúde na cidade de Curitiba no período de 2008 a 2011, com intuito de estabelecer elementos práticos para contribuição deste poder municipal para a consolidação das políticas públicas de saúde no município. Trata-se de uma pesquisa exploratória e aplicada, com uso de fonte de dados secundários e análise quantitativa das informações. Os projetos da área da saúde representam 16,2% do total de projetos lei ordinária, totalizando 96 projetos, esses focam em grande parte da população e fortalecem algumas datas comemorativas. Quanto aos partidos políticos, pode-se observar que há partidos com menor quantidade de vereadores, entretanto propuseram mais projetos lei do que outros partidos políticos com maior número de vereadores. Os resultados demonstram a necessidade de maior integração e participação da sociedade no Conselho Municipal de Saúde e no debate das proposições do Poder Legislativo municipal para fortalecer o papel local no desenvolvimento e aprimoramento da política pública em saúde.
Fibromyalgia in Spondyloarthritis: Effect on Disease Activity Assessment in Clinical Practice
Authors: Wach Jean , Letroublon Marie-Claude , Coury Fabienne , Tebib Jacques Guy 
Published: September 2016

Objective.Spondyloarthritis (SpA) is the second most frequent inflammatory rheumatic disease, characterized by spinal involvement, peripheral arthritis, or enthesitis with marked pain, stiffness, and fatigue. Fibromyalgia (FM) may be associated with SpA, and shares some common symptoms. We aimed to determine how FM influences assessment of SpA disease activity, which is mainly dependent on patient-based outcome measures such as the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) or the Ankylosing Spondylitis Disease Activity Score (ASDAS).Methods.This single-center cross-sectional study included consecutive patients with SpA according to the Assessment of SpondyloArthritis International Society criteria. FM was diagnosed according to the 1990 American College of Rheumatology criteria. Patient characteristics, BASDAI, ASDAS/C-reactive protein (CRP), Bath Ankylosing Spondylitis Functional Index, Bath Ankylosing Spondylitis Metrology Index, and the Medical Outcomes Study Short Form-36 questionnaire were recorded and compared.Results.The study included 103 patients with SpA; 81 with axial and 22 with peripheral forms. Eighteen patients presented with concomitant FM, of whom 12 had axial SpA and 6 peripheral SpA. Demographic characteristics did not differ except for sex, with a female predominance in the FM group that was more marked in peripheral forms. BASDAI was higher in patients with FM [median (IQR): 4.2 (4.2) vs 2.2 (3.1); p = 0.0068], whereas ASDAS-CRP was not significantly different [median (IQR): 2.7 (2) vs 2 (1.3); p = 0.1264]. Nevertheless, median ASDAS-CRP corresponded to high disease activity in patients with SpA or FM compared with moderate activity in non-FM patients.Conclusion.FM is a frequent comorbidity in patients with SpA, especially in peripheral forms. In patients with SpA-FM, disease activity may be overestimated when measured by BASDAI and to a lesser extent by ASDAS-CRP, and this overestimation could lead to inappropriate treatment escalation.
Macular Retinal Sublayer Thicknesses in G11778A Leber Hereditary Optic Neuropathy
Authors: Lam Byron L. , Burke Samuel P. , Wang Mindy X. , Nadayil Gloria A. , Rosa Potyra R. , Gregori Giovanni , Feuer William J. , Cuprill-Nilson Sophia , Vandenbroucke Ruth , Zhang Xiaojun , Guy John 
Published: September 2016

BACKGROUND AND OBJECTIVE:
To determine macular retinal sublayer thickness changes in G11778A Leber hereditary optic neuropathy (LHON).

PATIENTS AND METHODS:
The authors performed a cross-sectional study by segmenting spectral-domain Cirrus OCT (Carl Zeiss Meditec, Dublin, CA) 512 × 128 macular cube scans from a prospective, observational study of G11778A LHON. The thickness of the retinal sublayers of LHON affected subjects and asymptomatic carriers were compared to those of a normal group.

RESULTS:

The study included 20 LHON-affected subjects (13 males; age: 31 years ± 14 years, range: 10 years to 61 years; time since onset of visual loss: 5.9 years ± 8.7 years; 0.4–29.8), 31 asymptomatic LHON carriers (five males; age: 38 years ± 18 years, range: 9 years to 65 years), and 14 normal subjects (five males; age: 39 years ± 13 years, range: 23 years to 61 years). The retinal sublayer thickness parameters were not significantly correlated with age in any of the groups. There were no differences between carriers and normal subjects for thickness of total retina or any sublayer. Affected LHON retinal nerve fiber layer (RNFL) and ganglion cell layer plus inner plexiform layer (GCL+IPL) were thinner, whereas the photoreceptor outer segment (OS) layer was thicker than carriers and normal subjects (
P
values ranged from .042 to < .001), except for the OS layer in the inferior inner ring and temporal outer ring. Differences between groups were not significant in the inner nuclear layer plus outer plexiform layer (INL+OPL). The affected LHON outer nuclear layer plus inner segment layer was thicker in some quadrants, and the affected LHON choroid layer was generally thinner than carriers and normal subjects; however, these differences were not significant after accounting for age.

CONCLUSION:
LHON-affected patients have thickened photoreceptor OS layers in spite of having thinner RNFL and GCL+IPL layers. The findings indicate LHON also has an effect on the morphology of the photoreceptors.

[
Ophthalmic Surg Lasers Imaging Retina
. 2016;47:802–810.]
Regional Changes in Choroidal Thickness in Branch Retinal Artery Occlusion
Authors: Bhullar Paramjit K. , Grewal Dilraj S. , Fekrat Sharon 
Published: September 2016

BACKGROUND AND OBJECTIVE:
To assess regional changes in choroidal thickness in the affected temporal hemifield of eyes with branch retinal artery occlusion (BRAO) compared to the unaffected temporal hemifield of the same eye and to fellow eyes.

PATIENTS AND METHODS:
Six eyes of six patients with unilateral BRAO with fellow eyes serving as controls. Using optical coherence tomography, choroidal thickness was measured at 49 points and averaged for each hemifield.

RESULTS:

In BRAO eyes, choroidal thickness was greater in the affected hemifield (209.5 µm ± 13.9 µm) compared to the unaffected hemifield (181.3 µm ± 8.9 µm;
P
= .001). In fellow-eyes, there was no difference between the two hemifields (180.3 µm ± 18.1 µm vs. 193.7 µm ± 16 µm;
P
= .39). The choroid was thicker in the affected BRAO eye hemifield compared to the corresponding fellow eye hemifield (209.5 µm ± 13.9 µm vs. 180.3 µm ± 18.1 µm;
P
= .01), whereas no difference was observed among unaffected BRAO eye hemifield and corresponding fellow eye hemifield (181.3 µm ± 8.9 µm vs. 193.7 µm ± 16 µm;
P
= .1). Subfoveal choroidal thickness between BRAO and fellow eyes was similar (185.5 µm ± 25.7 µm vs. 194.5 µm ± 20.8 µm;
P
= .4).

CONCLUSION:
The choroid was 15.6% thicker in the affected hemifield of BRAO eyes compared to the unaffected hemifield of same eye and 16.2% thicker than the corresponding hemifield in fellow eyes.

[
Ophthalmic Surg Lasers Imaging Retina
. 2016;47:811–818.]
SUSTAINABLE DESIGN IN PROJECT DELIVERY: A DISCUSSION ON CURRENT AND FUTURE TRENDS
Authors: Widjaja Karno 
Published: September 2016

INTRODUCTION Sustainability principles have become an integral part of the design and construction process for many new construction projects. The selection of the project delivery method (PDM) is extremely important in the effective execution of the project, and plays a critical role in establishing communication and coordination between the key entities: owner, architect, and contractor. The goal of this paper is to hopefully serve as a starting point for further discussion to improve on the AEC industry's current integration of sustainability principles in PDMs. The first step consists of an assessment of current project delivery systems from a sustainable design perspective. This is followed by a determination of the current limitations, and examination of the various disruptions in the industry. Various literature sources are analyzed to form a framework to discuss improvements and optimization strategies beyond the current system. Thereafter, proposed solutions are introduced at both stakeholders, as well as PDM scales. In this paper, the focus for the conducted analysis and proposed methodologies is predicated on new construction projects instead of retrofits due to the resources available. However, the principles can similarly be applied to retrofit scenarios as well, depending on the specific requirements of the individual project at play.
Les phonothèques de l’oral au carrefour de la recherche et de la culture
Authors: Pelen Jean-Noël 
Published: September 2016

Ce texte * correspond à l’introduction faite par Jean-Noël Pelen des rencontres sur les phonothèques de l’oral qui se sont tenues en 1990 à La Baume-lès-Aix. J.-N. Pelen était alors directeur du Centre de Recherches méditerranéennes sur les Ethnotextes, l’Histoire Orale et les Parlers régionaux (CREHOP, Université de Provence - CNRS). Ces journées étaient organisées par la Mission du Patrimoine Ethnologique (Ministère de la Culture), le Groupement de Recherches Nord-Méditerranée, le Groupement de Recherches Atlas linguistiques, Parlers et cultures des régions de France (GdR 009), l’Université de Provence, et avec le soutien de l’Association P.O.L. SUD et de l’AFAS, alors dénommée Association Française d’Archives Sonores et présidée par Marie-France Calas.
Le fonds de disques 78 tours Pathé de musique arabe et orientale donné aux Archives de la Parole et au Musée de la Parole et du Geste de l’Université de Paris : 1911 - 1930
Authors: Ouijjani Hinda 
Published: September 2016

Etudiante en master 2 professionnel « Histoire et médias » du département d’Histoire de l’UFR des Lettres et Sciences humaines de l’Université Paris-Est Créteil, Hinda Ouijjani a effectué en 2011 un stage de cinq mois au Service des documents sonores du Département de l’audiovisuel de la Bibliothèque nationale de France (BnF). Durant ce stage, elle a inventorié et catalogué un fonds de 700 disques 78 tours de musiques arabe et orientale donné, entre 1911 et 1930, par la firme Pathé aux Archives de la Parole, devenu Musée de la Parole et du Geste de l’Université de Paris en 1928. L’auteur restitue ici l’analyse de ce fonds, publiée en deux parties dans les bulletins de l’AFAS n° 38 et 39.
Long-Lived CD4+IFN-γ+ T Cells rather than Short-Lived CD4+IFN-γ+IL-10+ T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection
Authors: Villegas-Mendez Ana , Inkson Colette A. , Shaw Tovah N. , Strangward Patrick , Couper Kevin N. 
Published: September 2016

Abstract
CD4+ T cells that produce IFN-γ are the source of host-protective IL-10 during primary infection with a number of different pathogens, including Plasmodium spp. The fate of these CD4+IFN-γ+IL-10+ T cells following clearance of primary infection and their subsequent influence on the course of repeated infections is, however, presently unknown. In this study, utilizing IFN-γ–yellow fluorescent protein (YFP) and IL-10–GFP dual reporter mice, we show that primary malaria infection–induced CD4+YFP+GFP+ T cells have limited memory potential, do not stably express IL-10, and are disproportionately lost from the Ag-experienced CD4+ T cell memory population during the maintenance phase postinfection. CD4+YFP+GFP+ T cells generally exhibited a short-lived effector rather than effector memory T cell phenotype postinfection and expressed high levels of PD-1, Lag-3, and TIGIT, indicative of cellular exhaustion. Consistently, the surviving CD4+YFP+GFP+ T cell–derived cells were unresponsive and failed to proliferate during the early phase of secondary infection. In contrast, CD4+YFP+GFP− T cell–derived cells expanded rapidly and upregulated IL-10 expression during secondary infection. Correspondingly, CD4+ T cells were the major producers within an accelerated and amplified IL-10 response during the early stage of secondary malaria infection. Notably, IL-10 exerted quantitatively stronger regulatory effects on innate and CD4+ T cell responses during primary and secondary infections, respectively. The results in this study significantly improve our understanding of the durability of IL-10–producing CD4+ T cells postinfection and provide information on how IL-10 may contribute to optimized parasite control and prevention of immune-mediated pathology during repeated malaria infections.
Neurochemistry study of spinal cord in non-human primate (Sapajus spp.)
Authors: Torres-da-Silva K.R. , Da Silva A.V. , Barioni N.O. , Tessarin G.W.L. , De Oliveira J.A. , Ervolino E. , Horta-Junior J.A.C. , Casatti C.A. 
Published: September 2016

<p class="Normale1">The spinal cord is involved in local, ascending and descending neural pathways. Few studies analyzed the distribution of neuromediators in the laminae of non-human primates along all segments. The present study described the classic neuromediators in the spinal cord of the non-human primate <em>Sapajus spp.</em> through histochemical and immunohistochemical methods. Nicotinamide adenine dinucleotide hydrogen phosphate-diaphorase (NADPH-d) method showed neuronal somata in the intermediolateral column (IML), central cervical nucleus (CCN), laminae I, II, III, IV, V, VI, VII, VIII and X, besides dense presence of nerve fibers in laminae II and IX. Acetylcholinesterase (AChE) activity was evident in the neuronal somata in laminae V, VI, VII, VIII, IX, CCN, IML and in the Clarke’s column (CC). Immunohistochemistry data revealed neuronal nitric oxide synthase (nNOS) immunoreactivity in neuronal somata and in fibers of laminae I, II, III, VII, VIII, X and IML; choline acetyltransferase (ChAT) in neuronal somata and in fibers of laminae VII, VIII and IX; calcitonin gene-related peptide (CGRP) was noticed in<strong> </strong>neuronal somata of lamina IX and in nerve fibers of laminae I, II, III, IV, V, VI and VII; substance P (SP) in nerve fibers of laminae I, II, III, IV, V, VI, VII, VIII, IX, X, CCN, CC and IML; serotonin (5-HT) and vesicular glutamate transporter-1 (VGLUT1) was noticed in nerve fibers of all laminae; somatostatin (SOM) in<strong> </strong>neuronal somata of laminae III, IV, V, VI, VII, VIII and IX and nerve fibers in laminae I, II, V, VI, VII, X and IML; calbindin (Cb) in neuronal somata of laminae I, II, VI, VII, IX and X; parvalbumin (PV) was found in neuronal somata and in nerve fibers of laminae III, IV, V, VI, VII, VIII, IX and CC; finally, gamma-amino butyric acid (GABA) was present in neuronal somata of laminae V, VI, VII, VIII, IX and X. This study revealed interesting results concerning the chemoarchitecture of the <em>Sapajus </em>spp<em>.</em> spinal cord with a distribution pattern mostly similar to other mammals. The data corroborate the result described in literature, except for some differences in CGRP, SP, Cb, PV and GABA immunoreactivities present in neuronal somata and in nerve fibers. This could suggest certain specificity for the neurochemistry distribution in this non-human primate species, besides adding relevant data to support further studies related to processes involving spinal cord components.</p>
A Swedish Population-based Study of Adverse Birth Outcomes among Pregnant Women Treated with Buprenorphine or Methadone: Preliminary Findings
Authors: Wurst Keele E. , Zedler Barbara K. , Joyce Andrew R. , Sasinowski Maciek , Murrelle E. Lenn 
Published: September 2016

Background Untreated opioid dependence in pregnant women is associated with adverse birth outcomes. Buprenorphine and methadone are options for opioid agonist medication-assisted treatment during pregnancy. Objective The aim of this study was to describe adverse birth outcomes observed with buprenorphine or methadone treatment compared to the general population in Sweden. Methods Pregnant women and their corresponding births during 2005–2011 were identified in the Swedish Medical Birth Register. Data on stillbirth, neonatal/infant death, mode of delivery, gestational age at birth, Apgar score, growth outcomes, neonatal abstinence syndrome, and congenital malformations were examined. Frequencies were compared using two-sided Fisher's exact tests. Unadjusted estimates of birth outcomes for women treated with buprenorphine or methadone were compared to the registered general population. Results A total of 746,257 pregnancies among 538,178 unique women resulted in 746,485 live births. Among the 194 women treated with buprenorphine ( N = 176) or methadone ( N = 52), no stillbirths or neonatal/infant deaths occurred. Neonatal abstinence syndrome developed in 23.3% and 38.5% of infants born to mothers treated with buprenorphine and methadone, respectively. The frequency of the selected adverse birth outcomes assessed in women treated with buprenorphine as compared to the general population was not significantly different. However, a significantly higher frequency of preterm birth and congenital malformations was observed in women treated with methadone as compared to the general population. Compared with the general population, methadone-treated women were significantly older than buprenorphine-treated women, and both treatment groups began prenatal care later, were more likely to smoke cigarettes, and did not cohabitate with the baby's father. Conclusions An increased frequency of the selected adverse birth outcomes was not observed with buprenorphine treatment during pregnancy. Twofold increased frequency of preterm birth [2.21 (1.11, 4,41)] and congenital malformations [2.05 (1.08, 3.87)] was observed in the methadone group, which may be partly explained by older average maternal age and differences in other measured and unmeasured confounders.
Characterization of Positive Links and the s-invariant for Links
Authors: Abe Tetsuya , Tagami Keiji 
Published: September 2016

AbstractWe characterize positive links in terms of strong quasipositivity, homogeneity, and the
value of Rasmussen and Beliakova-Wehrli's s-invariant. We also study almost positive links, and in
particular, determine the s-invariants of almost positive links. This result suggests that all almost
positive links might be strongly quasipositive. On the other hand, it implies that almost positive
links are never homogeneous links
Unusual conversations: A reflection on the mechanics of internationally engaged public scholarship
Authors: Damiani Jonathan 
Published: September 2016

This article analyses the civic engagement pathways of researchers from the Asia-Pacific and the United States in an effort to see how the principles of what American scholars consider publicly engaged research and creative practice are being enacted in research sites across the globe. The purpose of this ongoing project is to focus on finding ways of connecting American scholars with a network of higher education and research institutions that hold a commitment and passion for social responsibility and civic engagement as it impacts education, research and service for community development overseas. The narrative includes the voices and perspectives of colleagues dedicated to engaged scholarship from across the new region in which I work (the Asia-Pacific), alongside the voices of some of Imagining America’s (IA) 2014 National Conference participants. These conversations serve as a critical reflection on the mechanics of doing public scholarship overseas and frame a new model of internationally engaged scholarship.Keywords: Internationally engaged public scholarship, unusual conversations
Supporting communities of practice: A reflection on the benefits and challenges facing communities of practice for research and engagement in nursing
Authors: De Waal Maretha , Khumisi Oumiki 
Published: September 2016

Because of its potential self-sustainability, communities of practice may serve as useful practice-based knowledge sharing platforms for collaborative research and training, and thereby enhance development of human resources in the health sector. However, communities of practice are complex structures and need support from their host organisations and commitment from their members. This article examines the diverse ways in which communities of nurse educators and practitioners who were part of a funded program in Tshwane District, South Africa evolved over a period of seven years. Adopting an ethnographic approach of reflexivity and learning, we compared and analysed the ways in which the communities of practice became sustainable over time. Our recommendations for institutional support of communities of practice in the health sector are based on the lessons we learned during the program that contributed to the configuration and reconfiguration of some of our communities of practice and the disengagement of others. We believe that our findings may have implications for replicability and sustainability of other communities of practice.Keywords: collaborative learning, collective knowledge, self-sustainability
Profitability of Organic Vegetable Production via Sod Based Rotation and Conventional Versus Strip Tillage in the Southern Coastal Plain
Authors: Ahmadiani Mona , Li Chun , Liu Yaqin , Fonsah Esendugue Greg , Bliss Christine , Brodbeck Brent , Andersen Peter 
Published: September 2016

<p class="sar-body"><span lang="EN-US">There are little economic data concerning the profitability of organic vegetable crops in the Southern Coastal Plain, especially in reference to sod-based rotation and tillage alternatives. A three-year experiment was conducted at the North Florida Research and Education Center-Quincy involving a crop rotation sequence of oats and rye (winter), bush beans (spring), soybean (summer) and broccoli (fall). Bush beans and broccoli were the cash crops. This paper presents analyses of the riskiness of organic production utilizing years in bahiagrass prior to initiating the crop rotation sequence and conventional tillage (CT) versus strip tillage (ST). Methods of “Risk-rated enterprise budget” and “Analyses of Variance-Covariance Matrix (ANOVA)” were utilized for determining relative profitability, and coefficient of variation was applied for measuring riskiness of each treatment. Three years of bahiagrass prior to initiating the crop rotation sequence, in combination with conventional tillage, had the highest profitability and ranked as the least risky scenario. The second most profitable treatment was conventional tillage with four years of bahiagrass. Focusing on strip tillage, four years of bahiagrass with strip-tillage ranked third in term of profitability.</span></p>
Het belonen van commissarissen in aandelen: alignment versus onafhankelijkheid?
Authors: Dijkhuizen T.C.A. 
Published: September 2016

Het belonen van commissarissen in aandelen: alignment versus onafhankelijkheid?
In een tijdsgewricht waarin de aan bestuurders van Nederlandse beursvennootschappen toegekende beloningen steeds breed worden uitgemeten in de landelijke media en publieke ophef tot gevolg hebben, is het evident dat de beloning als onderwerp terug zou komen in het consultatievoorstel tot herziening van de Corporate Governance Code. De auteur bespreekt de voorgestelde principes en best practice bepalingen over de beloning, waarbij hij ingaat op het voorstel om het mogelijk te maken commissarissen in aandelen te belonen. De vraag rijst of met het belonen van commissarissen in de vorm een variabele beloning de onafhankelijkheid van deze commissarissen in het geding komt.