bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of N, P, and Fe availability on Braarudosphaera bigelowii, Trichodesmium, Crocosphaera, and noncyanobacterial diazotrophs: a review
Authors: Cao Wenhui , Yang Qunhui , Ji Fuwu , Liu Cheng 
Published: October 2024

Marine biological nitrogen fixation (BNF) is crucial for introducing “new nitrogen” into the oceans. Over the past 30 years, numerous laboratory and on-board culture experiments have been conducted studying the effects of nutrients such as total dissolved nitrogen (TDN), total dissolved phosphorus (TDP), and dissolved iron (DFe) on marine diazotrophs such as Braarudosphaera bigelowii (B. bigelowii), Trichodesmium, Crocosphaera and noncyanobacterial diazotrophs (NCDs). Most studies concluded that elevated dissolved inorganic nitrogen levels inhibit nitrogen fixation in Trichodesmium, promote its growth, and have minimal effect on B. bigelowii. The impact on NCDs is unclear. Moreover, elevated dissolved inorganic phosphorus (DIP) levels can promote individual growth, population growth, and nitrogen fixation in most diazotrophs in P-limited marine environments. Dissolved organic phosphorus is a potential phosphorous source for diazotrophs in low-DIP environments. Elevated DFe can promote population growth and nitrogen fixation in diazotrophs in Fe-limited marine environments. At present, most diazotrophs have yet to achieve pure culture. Moreover, the effect of nutrients on diazotrophs is mainly limited to the study of a single nutrient, which cannot accurately reflect the actual Marine environment where diazotrophs live. As a result, our understanding of the effect of nutrients on diazotrophs is still insufficient. Future research focusing on the issues above and the development of innovative technologies and methodologies to investigate the impact of marine BNF is highly recommended, which will allow for a more precise assessment of the impact of marine BNF on global primary productivity while providing a scientific foundation for rational evaluation of ocean CO2 uptake and emissions.
Optimizing extubation success: a comparative analysis of time series algorithms and activation functions
Authors: Huang Kuo-Yang , Lin Ching-Hsiung , Chi Shu-Hua , Hsu Ying-Lin , Xu Jia-Lang 
Published: October 2024

BackgroundThe success and failure of extubation of patients with acute respiratory failure is a very important issue for clinicians, and the failure of the ventilator often leads to possible complications, which in turn leads to a lot of doubts about the medical treatment in the minds of the people, so in order to increase the success of extubation success of the doctors to prevent the possible complications, the present study compared different time series algorithms and different activation functions for the training and prediction of extubation success or failure models.MethodsThis study compared different time series algorithms and different activation functions for training and predicting the success or failure of the extubation model.ResultsThe results of this study using four validation methods show that the GRU model and Tanh’s model have a better predictive model for predicting the success or failure of the extubation and better predictive result of 94.44% can be obtained using Holdout cross-validation validation method.ConclusionThis study proposes a prediction method using GRU on the topic of extubation, and it can provide the doctors with the clinical application of extubation to give advice for reference.
The association of dietary insulinemic indices with PI3K, PTEN, and Akt gene expressions in visceral and subcutaneous adipose tissues among individuals undergoing abdominal surgery
Authors: Ahmadirad Hamid , Teymoori Farshad , Farhadnejad Hossein , Shimi Ghazaleh , Asghari Golaleh , Yuzbashian Emad , Zarkesh Maryam , Mirmiran Parvin , Khalaj Alireza 
Published: October 2024

Background/objectiveThe current study investigates the association between dietary insulinemic indices and Akt, PTEN, and PI3K gene expressions in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) among individuals undergoing abdominal surgery.Materials and methodsThis cross-sectional study was conducted on 176 individuals, aged 18–84 years, who had undergone abdominal surgery. The participants were classified based on body mass index (BMI) as normal (BMI &lt; 25 kg/m2), overweight (BMI = 25–29.9 kg/m2), and obese (BMI ≥ 30 kg/m2). The food frequency questionnaire was used to determine dietary glycemic and insulinemic indices. Real-time polymerase chain reaction was conducted for the expression of PI3K, PTEN, and Akt genes.ResultsIn the final adjusted model, in normal-weight patients, there was an inverse relationship between the lifestyle with a higher insulinemic potential and the PI3K gene expression in VAT. In addition, there was an inverse association between dietary insulin load and the Akt gene expression in VAT. However, a higher glycemic index was positively associated with the PTEN gene expression in VAT. In overweight patients, a high insulinemic potential of the diet was associated with higher PTEN gene expression in VAT. In obese individuals, there were positive associations between lifestyle index for insulin resistance and hyperinsulinemia and the PI3K gene expression in VAT. Moreover, the higher insulinemic potential of diet and lifestyle was positively related to a higher expression of the PTEN and Akt genes in VAT.ConclusionOur findings revealed that high insulinemic lifestyles and dietary patterns may be related to the expression of PI3K, PTEN, and Akt in adipose tissues.
Instrumented measures of sedentary behavior and physical activity are associated with depression among children and adolescents: a systematic review and dose–response meta-analysis of observational studies
Authors: Lu Songtao , Sun Jun , Guo Zhiguang , Yi Mingyu , Zhang Yuheng , Wang Jiali , Wang Yue 
Published: October 2024

BackgroundHigher sedentary behavior (SB) and lower physical activity (PA) are associated with negative physical and mental health outcomes. SB and PA can be objectively assessed using inertial sensors to evaluate body movements. This study aimed to quantify the association between instrumented measures of SB (i-SB) and PA (i-PA) and depression among children and adolescents using a systematic review and meta-analysis of observational studies.MethodsAn electronic search was conducted on six databases up to May 12, 2024. A dose–response meta-analysis was conducted to determine the association between i-SB and i-PA and depression, expressed as odds ratios (ORs) and 95% confidence intervals (CIs).ResultsFive cross-sectional and 11 longitudinal studies comprising 26,109 participants met the inclusion criteria. Comparing the most sedentary with the least sedentary groups of participants resulted in a pooled ORs of 1.05 (95% CI 0.94–1.16). Comparing the least active with the most active groups of participants resulted in pooled ORs of 0.93 (95% CI 0.84–1.07), 0.89 (95% CI 0.79–1.00), 0.83 (95% CI 0.66–0.99), and 0.73 (95% CI 0.58–0.89) for light, moderate-to-vigorous (MV), vigorous, and total PA, respectively. Robust error meta-regression analyses showed clear dose–response relationships between i-SB and i-MVPA and depression.ConclusionBoth i-SB and i-PA were significantly associated with risk of depression in children and adolescents, which may become non-significant after mutual adjustment for i-PA and i-SB.Systematic review registration[https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=546666], identifier [CRD42024546666].
Seclusion and mechanical restraint in the wake of the COVID-19 pandemic: an increased use in mental health settings
Authors: Goulet Marie-Hélène , Cassivi Christine , Hupé Catherine , Jean-Baptiste Francelyne , Dumais Alexandre 
Published: October 2024

PurposeCOVID-19 pandemic-related restrictions have significantly changed the environment and the delivery of direct care in all health services, including psychiatric hospitals. The aim of the study is two-fold: 1) to retrospectively assess the incidence of seclusion and mechanical restraint in a Quebec mental health hospital over 4 years; and 2) to assess the impact of the COVID-19 pandemic on their incidence.MethodsWe conducted a retrospective study based on medical records from a Quebec mental health hospital collected (a) from April 2016 to March 2019), (b) from April 2019 to March 2020 (pre-COVID onset), and (c) from April 2020 to March 2021 (post-COVID onset). Descriptive statistics, chi square tests, Mann-Kendall test and Welch’s t-test were performed.ResultsFollowing several years during which the use of restrictive measures remained stable, we have noted a significant increase within the first year following the COVID-19 pandemic. This increase can be seen in the use of both seclusion and restraints, which have risen 205% and 170% respectively.ConclusionThere are a multitude of factors associated with the incidence of seclusion and restraint that have the potential to be triggered during emergencies and global crisis situations, impacting in turn the rights of an already vulnerable population.
Descriptive analysis of 1,048 presentations in the first five years of a zero-suicide framework in a child and youth mental health service in Australia
Authors: Branjerdporn Grace , McCosker Laura K. , Jackson Derek , Gillespie Kerri M. , McDowell Sarah , Chand Sandeep , Joshi Hitesh , Pisani Anthony R. , Stapelberg Nicolas J. C. , Welch Matthew , Turner Kathryn , Woerwag-Mehta Sabine 
Published: October 2024

IntroductionSuicide in children is a significant and unacceptable global phenomenon. This paper provides a descriptive overview of the children presenting in the first five years (2016-2021) of the implementation of the Zero Suicide Framework (ZSF) and Suicide Prevention Pathway (SPP) at a Child and Youth Mental Health Service in Queensland, Australia.MethodsBasic demographic variables (sex, age, socioeconomic status), and changes in presentations over time, are presented for 1,048 children. Completeness of selected SPP components relating to care planning and universal interventions are examined as an indicator of fidelity to the SPP model of care. The paper then focuses on the cohort of children who received care through the SPP in 2020, describing their demographic characteristics and baseline clinical scores.ResultThere was an increase in admissions each year and children presented with a diverse range of clinical needs. The SPP greatly increased the provision of first line interventions for patients.DiscussionA standardized approach to suicide prevention improves consistency in management. These findings may inform the use of the ZSF/SPP in child mental health settings globally.
Prevalence and allergy-related risk factors of overactive bladder in children in Northeast China
Authors: Zheng Yue , Yin Lu , Wang Xiuli , Zhao Chengguang , Du Yue 
Published: October 2024

ObjectiveThe objective of this study was to investigate the prevalence of overactive bladder (OAB) and its risk factors related to allergies among children in Northeastern China.MethodsA community survey on OAB was conducted in Northeast China from 1 April 2022 to 30 April 2022. The survey targeted children aged 5–14 years and utilized questionnaires. A total of 1,394 children were enrolled, and their parents were requested to fill out a questionnaire to provide basic information about the children. This encompassed details regarding the presence or absence of urgent urination unrelated to urinary tract infection, urinary tract infection, allergic rhinitis, asthma or cough variant asthma, atopic dermatitis, anaphylactic conjunctivitis, urticaria, constipation, and attention deficit hyperactivity disorder (ADHD). The prevalence of OAB was calculated. The chi-squared test was used to analyze OAB-related factors, which were subsequently included in the logistic regression model for multi-factor analysis.ResultsThe overall OAB prevalence was 10.7% (120 of 1,121), including 47 mild cases (39.2%), 71 moderate cases (59.1%), and 2 severe cases (1.7%). OAB prevalence decreased with age (p &lt; 0.05). The risk factors associated with OAB were allergic asthma (OR = 1.87, 95%CI: 1.12–3.13), atopic dermatitis (OR = 2.45, 95%CI: 1.61–3.73), anaphylactic conjunctivitis (OR = 1.61, 95%CI: 1.07–2.42), and urticaria (OR = 1.93, 95%CI: 1.40–2.66).ConclusionOAB prevalence among children in Northeastern China was found to be 10.7%, with its risk factors being allergic asthma, anaphylactic conjunctivitis, urticaria, and atopic dermatitis. The identification of allergy-related risk factors may provide new ideas for the prevention and treatment of OAB.
Exploring the utility of bioaerosol metagenomics compared to PCRs for swine pathogen surveillance
Authors: Muwonge Adrian , Gerber Priscilla F. , Wee Bryan A. , Thomson Jill , Wang Jingjing , Halbur Patrick G. , Opriessnig Tanja 
Published: October 2024

IntroductionPathogen introduction and transmission at the farm, regional, or national level are associated with reduced animal welfare and negative impacts on herd economics. Ongoing infectious disease surveillance, active or passive, is therefore of high importance. For optimal resolution, each pig is sampled individually, for example by collecting blood or nasal swabs. In recent years, oral fluids have become very useful for population surveillance at the pen level. Another alternative is sampling the air to capture pathogens circulating across the entire barn via bioaerosols.ObjectiveThis study aimed to examine the potential utility of bioaerosol metagenomics for pathogen detection on pig farms.MethodsBioaerosols via automated air sampler, and oral fluid via pen-based ropes, were collected from each of two Scottish indoor pig farms. All samples were subjected to conventional routine bacterial isolation. Total genomic nucleic acids were extracted for PCR screening for three pig DNA viruses, three bacterial Mycoplasma species and an RNA virus. Illumina shotgun metagenomic sequencing was also conducted.ResultsOral fluids contained more DNA compared to bioaerosol samples. DNA integrity exhibited limited impact on PCR or sequence yield. While Streptococcus suis could be cultured from a single oral fluid sample, reads mapped to S. suis were detectable in all metagenomic samples. Other bacterial pig pathogens, including Mycoplasma hyorhinis, M. hyopneumoniae and M. hyosynoviae, were detected in oral fluid and aerosols by PCR and metagenomics. One of the two farms was PRRSV positive, and the virus was detectable via PCR in oral fluids but not in bioaerosols. Antimicrobial resistance (AMR) gene profiles had less variation between bioaerosols and oral fluids. Some identified AMR genes had strikingly similar abundance overall.ConclusionOverall, these findings indicate that there is potential utility of bioaerosol metagenomics for pathogen surveillance on pig farms; however, more research is needed for technical and cost optimization to allow for routine pathogen detection on livestock farms.
Histopathological Characteristics of Percutaneous Endomyocardial Biopsy in Heart Transplant Rejection Surveillance: A Single Center Experience
Authors: Farcas Anca Otilia , Stoica Mihai Ciprian , Voidazan Septimiu , Maier Ioana Maria , Maier Adrian Cornel , Suciu Horatiu , Sin Anca Ileana 
Published: October 2024

Background: Heart transplantation (HT) remains the ultimate treatment for end-stage heart failure. An endomyocardial biopsy (EMB) is “the gold standard” diagnostic procedure used in HT rejection surveillance. The aim of this study is to provide a detailed analysis of the histopathological characteristics of the EMB and to investigate if there is a correlation between some histopathological changes, such as fibrosis, vasculitis, Quilty effect (Q.E.), myocytes damage, and the presence of episodes of acute rejection. Methods: In this retrospective study, 200 EMBs were included, coming from 65 patients transplanted in the Emergency Institute for Cardiovascular Diseases and Transplantation (ICvDT) Targu Mures between 2012 and 2024. Fibrosis, vasculitis, Q.E., myocyte damage, etc., were microscopically evaluated to see if these parameters correlate with rejection episodes. Results: The mean age was 38.18 years (SD 15.67), 25% of biopsies being recorded in the 41–50 age group. 77.14% of total acute cellular rejection (ACR) was of mild rejection, with most registered in the 11–20 age group; the cases of severe rejection being recorded in the 41–50 age group. Antibody-mediated rejection (AMR) was recorded more frequently in women with a representation of 23.4%, compared to 8.5% of men. 86.7% (39 cases) of the total number of EMBs with fibrosis score 3 and 71.4% (15 cases) of the total EMBs with fibrosis score 2 were recorded in men, compared to the 28.6% (6 cases) of fibrosis score 2 recorded in women (p = 0.013). 50.0% of all the EMB recorded in the 61–70 age group showed fibrosis score 3, compared to 34.8% of those from the 21–30 age group. The Q.E. was identified in 13% of the biopsies and, in some patients, it was observed across 3–4 successive biopsies. Mild vasculitis was associated in 34.9% of cases with ISHLT ≥ 1R and moderate vasculitis was associated in 87.5% of cases with ISHLT ≥ 1R. Conclusions: Fibrosis was detected much more frequently in men and in the 61–70 age group. In addition to the histopathological changes specific to acute rejection, there are other pathological changes, such as the Q.E., and vasculitis and myocytes damage and disarray, that seem to suggest a close connection with rejection, but extensive studies are needed to confirm this.
Determinación de la población eosinofílica en bovinos de la ganadería FACIAG-UTB tratados con autohemoterapia
Authors: Ponce Cepeda Edison , Casierra Cardenaz Angel , Pérez Foyaín Katriana 
Published: October 2024

La AHT, o Autohemoterapia, es un tratamiento que consiste en la reintroducción de sangre autóloga en el organismo para mejorar la respuesta inmune. Este procedimiento se realiza extrayendo sangre de un animal y administrándola nuevamente, generalmente de forma intramuscular. El objetivo de la presente investigación fue evaluar el comportamiento de los eosinófilos en los sujetos de estudio antes y después de la aplicación de autohemoterapia. Se llevó a cabo un estudio experimental en la Universidad Técnica de Babahoyo, utilizando un enfoque cuantitativo con 12 hembras bovinas divididas en dos grupos (dosis de 20 ml y 15 ml de sangre autóloga). Se realizó un hemograma inicial antes del tratamiento y se administró la sangre en la tuberosidad iliaca y caudal. Se tomaron muestras de sangre semanalmente durante cuatro semanas para evaluar la población de eosinófilos, utilizando el equipo IDEXX para el análisis. Los resultados mostraron que, aunque no hubo diferencias significativas en las primeras 24 horas, a partir de la primera semana, los grupos tratados con 15 ml y 20 ml mostraron incrementos significativos en los niveles de eosinófilos. La dosis de 15 ml presentó el valor más alto en la primera prueba, sugiriendo que la autohemoterapia mejora la respuesta inmune en bovinos, especialmente a partir de la primera semana tras el tratamiento.
Talento humano en la calidad de exportación de artesanía en fibra de alpaca
Authors: Huacani Sucasaca Yudy , Mamani Mamani Jesús , Mamani Mamani Ambhar Marjore , Copari Bustamante Roger 
Published: October 2024

La finalidad del estudio es analizar la incidencia del talento humano en la calidad de exportación de artesanía en fibra de alpaca en la Región Puno (Perú). El diseño metodológico responde a un tipo de investigación cuantitativa, no experimental, transversal, hipotético deductivo, el muestreo es aleatorio simple, el instrumento es la encuesta. Las dimensiones de la variable talento humano son explicados por la capacidad humana, la aptitud humana, competitividad humana y compromiso humano. Los resultados de la correlación de Pearson Pearson r = 0.67 y p valor de 0.000 demuestran la incidencia directa y significativa de la capacidad humana, la aptitud humana, competitividad humana y compromiso humano sobre la exportación de la artesanía en fibra de alpaca. Se concluye, tener en cuenta las medidas y estrategias para fortalecer las competencias del talento humano, capacidad, aptitud, competitividad y compromiso por su relación para la mejorar de la calidad de exportación de fibra de alpaca.
MUSEUM REPRESENTATION OF ICONOGRAPFY IN THE FIST YEARS OF SOVIET POWER
Authors: Матвеева Зоя Дмитриевна 
Published: October 2024

Статья посвящена репрезентации иконописи в музейном пространстве, изучению ее стратегий и конкретных практик, существовавших в первые годы советской власти. Анализ экспозиционно-выставочной деятельности музеев позволяет выделить два основополагающих подхода: согласно одному из них, икона представляется как художественно ценное произведение древнерусской живописи, согласно другому, икона показывается как предмет религиозного быта, иллюстрирующий историю религии, систему религиозной и нравственной философии древнерусского человека и сам этот быт в его конкретном реальном воплощении.
The article is devoted to the representation of icon painting in the museum space, the study of its strategies and specific practices that existed in the first years of Soviet power. Analysis of the exposition and exhibition activities of museums allows us to distinguish two fundamental approaches: according to one of them, the icon is presented as an artistically valuable work of ancient Russian painting, according to another, the icon is shown as an object of religious life, illustrating the history of religion, the system of religious and moral philosophy of ancient Russia man and this very life in its concrete real embodiment.
Authors: Чесняк Марина Геннадьевна 
Published: October 2024

Проводится анализ становления Г. К. Праве, как организатора музея и основоположника музейного дела в российском губернском городе начала XX века, определившего структуры и основные направления деятельности ставропольского музея. Автобиографические сведения представляют интерес для исследователей развития музейного дела в Майкопе, Ейске, Кропоткине, Краснодаре, Астрахани и Москве.
The author analyzes the formation of G.K. Prave as the organizer of the museum and the founder of museum business in the Russian provincial city of the early 20th century. He laid the foundations of the structure and the main activities of the Stavropol museum. Autobiographical information is of interest to researchers of the development of museum business in Maikop, Eisk, Kropotkin, Krasnodar, Astrakhan and Moscow
Authors: Горбунова Анастасия Александровна 
Published: October 2024

В статье рассматривается ряд аллегорических изображений Азии, созданных в России в первой половине XVIII века. Представляется, что они внесли вклад в формирование художественного образа мусульманского Востока в русском искусстве. Выявляются изобразительные источники этих аллегорий, исследуется их иконография, определяются основные восточные формы и мотивы, вошедшие в художественный обиход отечественных мастеров и неизменно отождествляемые с мусульманским миром.
The article considers a number of allegorical images of Asia created in Russia in the first half of the 18th century. It seems that they contributed to the formation of the artistic image of the Muslim East in Russian art. The author considers the pictorial sources of these allegories, examines their iconography, identifies the main Oriental forms and motifs that have entered the artistic life of domestic masters and are invariably identified with the Muslim world
SEMANTIC A RICH HOW THE ATTRIBUTE POWER IN ANCIENT RUSSIA
Authors: Цветкова Галина Александровна 
Published: October 2024

Рассматривается социокультурная динамика представлений о богатстве как атрибуте власти и властителя в Древней Руси
The sociocultural dynamics of the ideas about wealth as an attribute of power and ruler in ancient Russia are considered.