bluuebunny/crossref_metadata_2025_split huggingface dataset:
Choosing Wisely: Resource Stewardship Education in Canadian Medical Schools
Authors: Muntyanu Anastasiya , Jebanesan Danusha , Kuling Peter 
Published: February 2017

AbstractResource stewardship has important implications in terms of healthcare costs as well as patient safety. Currently, there is limited formal teaching in the undergraduate curriculum in Canadian medical schools that addresses this topic. Recently, Choosing Wisely Canada has launched a student campaign to integrate Choosing Wisely concepts into the curriculum, hoping to challenge medical students into thinking about value-based healthcare and patient safety. This article intends to highlight need for resource stewardship education, including associated test costs and its impact on the healthcare system. The strategies currently being implemented at the University of Ottawa will also be discussed. RésuméL’intendance des ressources a d’importantes répercussions sur les coûts liés aux soins de santé, ainsi que sur la sécurité des patients. À l’heure actuelle, le curriculum de premier cycle des écoles de médecine canadiennes comporte peu d’enseignement formel à ce sujet. Récemment, Choisir avec soin (version francophone de « Choosing Wisely Canada ») a lancé une campagne étudiante pour intégrer les concepts de Choisir avec soin au curriculum, dans l’espoir d’encourager les étudiants en médecine à réfléchir aux soins de santé et à la sécurité des patients fondés sur la valeur. Cet article cherche à souligner l’importance de la formation sur l’intendance des ressources, incluant les coûts associés aux examens et leur impact sur le système de soins de santé. Les stratégies mises en œuvre à l’Université d’Ottawa à l’heure actuelle seront également présentées.
Study of the severity of stroke at the time of presentation in diabetic patients correlating with glycemic control
Authors: Patibandla Sivaji , Appikatla Tumbanatham , K. Jayasingh 
Published: February 2017

Background: Diabetes mellitus is a well-recognized risk factor for stroke. The NIHSS (National institute of health stroke scale) is a tool used objectively to quantify the impairment caused by a stroke. However, the effect of glycemic control regardless of the presence of DM on the clinical picture of stroke and its impact on the severity is not fully investigated. There are numerous studies on microvascular complications but there are only a few studies on strokes in diabetics. Therefore, this study was conducted to assess the impact of diabetes on the pattern and severity of stroke in our population.Methods: This is cross sectional observational study, carried at Mahatma Gandhi Medical College And Research Institute, Pondicherry, India from December 2014-15. Sixty patients who presented with features of stroke and satisfy inclusion criteria were enrolled in study. Stroke pattern was identified using CT scan and severity of stroke was assessed by NIHSS score. Statistical analysis was done by using chi-square test (p <0.005 = significant).Results: The mean age in patients was 61.683±12.97. The ratio of male to female was 2.1:1 showing male preponderance. With increase in HbA1c levels more number of cases were found to have severe stroke and it is statically significant (p = 0.0001) as per NIHSS score.Conclusions: In diabetic patients the severity of stroke is related to glycemic control. Higher the blood HbA1c level, more severe is the neurological impairment. Hence effective lowering of HbA1c level may reduce the occurrence of severe neurological impairment in diabetic patients. We suggest the need for routine monitoring of HbA1c level may be used as a measure for secondary prevention of stroke in diabetic patients.
Enhanced Lateral Bone Augmentation With a Perforated Resorbable Barrier Membrane
Authors: Carrion Julio A. , Wang Howard H. , Masselli Joseph , Iacono Vincent J. 
Published: February 2017

Introduction: To the best of the authors’ knowledge, this is the first case report to describe the use of a perforated resorbable barrier membrane (PRBM) to enhance lateral bone augmentation for implant site development.Case Presentation: A 41‐year‐old female presented to the Advanced Specialty Education Program in Periodontics at Stony Brook University, Stony Brook, New York, for implant consultation regarding a missing maxillary right lateral incisor. The tooth had been lost as a result of trauma 10 years prior to presentation. Clinical examination and radiographs showed significant horizontal ridge deficiency (<5 mm) that supported a staged intervention. Horizontal bone augmentation was performed following guided bone regeneration principles using a mineralized mixed corticocancellous (70:30) allograft followed by a PRBM. A cone beam computed tomography scan was obtained before surgery and 8 months after treatment, from which volumetric width changes were quantified. A bone biopsy was obtained at the time of implant placement to measure new vital bone (NVB) formation, residual graft (RG) particles, and connective tissue (CT) formation. Dimensional width changes were assessed during reentry for implant placement. The lateral bone gain was 5.0 mm, clinically and radiographically. Histologically, the amount of NVB formation, RG particles, and CT infiltration was 38.1%, 38.9%, and 23.1%, respectively. Implant placement was uneventful, with no further need for bone augmentation.Conclusions: Previous studies using similar techniques and regenerative materials have shown an average of 3.5 mm of horizontal bone augmentation. The use of a PRBM appeared to significantly enhance lateral bone augmentation. An ongoing clinical trial is underway to confirm these results.
The Implementationof Reference Services on the Library of State Universities in Surabaya
Authors: Dharma Gumelar Satya , Dwi P Andri , Anggraini Dini , Fuadillah Risma , Irlando K. Rona , Rakhma P. Mega , Firda Meyrinda , Setiyawan Agus , Yusna Darista , Islahnia R. Nindhita , Ahmad Gani Aditya , Eko B. Septian 
Published: February 2017

Layanan referensi perpustakaan merupakan layanan di perpustakaan yang secara langsung berhubungan dengan pembaca. Layanan referensi bertujuan untuk membantu para pengguna untuk merujuk ke sumber informasi yang dicari untuk kepentingan studi dan riset. Penelitian yang disusun dengan metode pendekatan deskriptif kuantitatif ini disusun dengan tujuan untuk Untuk mengetahui implementasi layanan berdasarkan koleksi, layanan, sarana dan prasarana serta sumber daya manusia pada layanan referensi yang ada di perpustakaan perguruan tinggi negeri di Surabaya yaitu di perpustakaan Universitas Negeri Surabaya, Universitas Airlangga, Universitas Islam Negeri Sunan Ampel, Universitas Pembangunan Nasional dan Institut Teknologi Sepuluh Nopember. Selain ingin mengetahui implementasinya tujuan dari penelitian ini yaitu untuk mengetahui kendala yang ada pada masing-masing layanan referensi. Responden pada penelitian ini adalah pustakawan referensi perpustakaan perguruan tinggi negeri di Surabaya. Metode pengumpulan data yang digunakan dalam penelitian ini yakni dengan menggunakan cara wawancara dan mengamati obyek penelitian yang berupa layanan referensi di seluruh perpustakaan perguruan tinggi negeri di kota Surabaya. Berdasarkan hasil pengamatan pada seluruh perpustakaan perguruan tinggi negeri di Surabaya yaitu sebagian besar dapat dikatakan masih rendah dalam pelayanan memberikan informasi melalui layanan referensi, dimana masih minimnya kegiatan yang diberikan pustakawan kepada pengguna, pengguna belum maksimal dalam memanfaatkan layanan bahkan koleksi pada layanan referensi. Karena pengguna lebih memilih mencari informasi elektronik melalui media online, sehingga berdampak tidak termanfaatkannya koleksi buku di layanan referensi, dimana fenomena tersebut menjadi kendala utama bagi layanan referensi perpustakaan perguruan tinggi negeri di Surabaya saat ini. Solusi yang dapat diambil untuk mengatasi permasalahan yang ada yaitu sebaiknya pihak perpustakaan menambahkan beberapa kegiatan layanan referensi seperti bimbingan pemustaka, bimbingan penelusuran dan juga mengadakan layanan e-referens untuk mengatasi pengguna yang lebih memilih sumber informasi dalam bentuk elektronik dibandingkan bentuk cetak.
Screening of In Vitro Antidiabetic Activity of Herbal Formulation Meshashringi
Authors: Poshan Kumar Sahu  , Pushpa Prasad  , Amit Roy  
Published: February 2017

Diabetes is diagnosis by hyperglycemia due to absolute or relative deficiency of insulin. Today’s lifestyle has been changed and sharp increase in the incidence and prevalence of diabetes mellitus has been perceived. The antidiabetic drugs reduce the gastrointestinal glucose production and absorption through the inhibition of carbohydrate digesting enzymes such as α- amylase and α-glucosidase. The present study was aimed to investigate in vitro antidiabetic activity of aqueous extract of Meshashringi formulation using enzyme inhibitory assays. The Meshashringi was evaluated against α-amylase, α-glucosidase and dipeptidyl peptidase-IV (DPP-IV). The Meshashringi revealed 50% inhibitory activity for α-amylase, α-glucosidase and DPP-IV enzyme at 106.00 μg/ml, 124.91 μg/ml and 160.67 μg/ml, respectively. Consequently, the standard drug Acarbose exhibited 50% inhibitory activity for α-amylase, α-glucosidase and DPP-IV enzyme at 37.80 μg/ml, 65.06 μg/ml and 48.22 μg/ml, respectively. The Meshashringi formulation produces dose dependent antidiabetic activity.
CO2 EOR Simulation in Unconventional Liquid Reservoirs: An Eagle Ford Case Study
Authors: Phi Tuan , Schechter David 
Published: February 2017

Abstract
The purpose of this work is to perform an improved method to optimize different CO2 Enhanced Oil Recovery (EOR) processes in unconventional liquid reservoirs, particularly in the volatile oil region of the Eagle Ford shale. Previous simulation studies of CO2 EOR in the unconventional liquid reservoirs were not done in full field-scale and were not history matched before applying CO2 EOR to the model. Without history matching step, the simulation might generate misleading results in CO2 EOR studies. The dual-porosity, structured grid model in this paper will be history-matched with actual data collected from the field to ensure the results of CO2 EOR study to be meaningful. In addition, we are implementing the simulation in the dual-porosity mode to account for the presence of natural fractures which have been observed on Eagle Ford outcrop.
First, all data will be gathered from public sources. These data include production reports, outcrop map, natural fracture, hydraulic fracture, geology, rock, and fluid. Multiple grid sizes and number of refinements for hydraulic fractures will be tested to ensure the accuracy of the simulation is preserved yet speed up computational time. Several sensitivity analyses will be conducted to investigate which parameters from the matrix system and the natural fracture system would have a significant impact on the incremental oil recovery. These parameters will be adjusted scientifically in the process of history matching to capture the primary depletion. Then, this history-matched model will be used to apply multiple CO2 EOR studies.
The history matched model suggests that matrix porosity in the volatile oil region of Eagle Ford shale might be overestimated in many previous investigations. Also, the sensitivity analyses show that the natural fracture permeability perpendicular to the direction of the horizontal well has a significant impact on oil rates in numerical simulation. Among different CO2 EOR methods tested in this research, huff-n-puff yields the most promising outcome as compared to continuous injection and WAG (Water-alternating-gas) in both oil production and economic performance in the volatile oil region of the Eagle Ford shale. In some circumstances, continuous injection method might yield great utilization efficiency but it contains high possibility of negative incremental oil recovery at the end of EOR practice due to pressure loss during CO2 injection time, incomplete miscible process between CO2 and residual oil, and viscous fingering.
EOR in Tight Reservoirs, Technical and Economical Feasibility
Authors: Joslin K. , Ghedan S. G. , Abraham A. M. , Pathak V. 
Published: February 2017

Abstract
Field experience indicates that primary depletion of tight oil formations, using multistage fractured horizontal wells, commonly recovers only 5 to 10% of OOIP. The impact of various EOR techniques on recovering additional oil from these formations is still not fully understood. This paper investigates the applicability of feasible EOR methods and determines their technical and economic success over the natural depletion process under different well and fracture designs. Additionally, the study investigates the minimum reservoir permeability required for success.
To achieve the objectives, both black oil and compositional simulation models were generated for a Western Canadian tight reservoir containing volatile oil. In addition to primary, the EOR recovery processes that were considered include waterflooding, immiscible-N2 and miscible-CO2 gas flooding. Combinations of these techniques, coupled with the effects of various well and fracture design parameters were technically explored, and economically ranked using a comprehensive economic analysis. Furthermore, the optimal case of each process was subjected to sensitivity on matrix permeability to determine the minimum permeability at which these methods can be applicable.
In the EOR scenarios evaluated, the highest cumulative oil produced was associated with the closest well and fracture spacing, and longest fracture half length. With a larger well spacing (in the order of 400 m), the wells were found to be too far apart to offer any benefit from any EOR technique. Additionally, the capital expenditure of tight-oil projects is high and therefore greatly influences the economic success. Several scenarios yielded similar NPV values, however, the IRR performances and CAPEX requirements helped further evaluate and rank the scenarios.
For the reservoir model used, waterflood was found to be uneconomical at the initial permeability levels investigated (around 0.3 md) and required a minimum permeability threshold (1 mD) to become profitable. The primary recovery mechanisms in waterflooding are pressure maintenance and areal sweep, which were more pronounced in the N 2flood. This was the best recovery technique based on NPV. However, the best recovery technique based on oil recovery was the miscible-CO2 flood. It offered an increase in oil recovery factor from 11% to 23% over the best natural depletion case, which was a result of increased oil mobility by dissolution of CO2. At lower permeability values (down to 0.03 mD) immiscible-N2 flood became the most effective method via pressure maintenance within the drainage area. For even tighter reservoirs (under 0.03mD), natural depletion remained the best option for this reservoir.
This paper provides an elaborate workflow for evaluating and optimizing EOR techniques in tight oil formations through an integrated modeling approach. It helps to identify the most technically and economically proficient techniques under different levels of permeability, well spacing and fracture parameters.
Experimental Study and Modeling of Cryogenic Fracturing Treatment of Synthetic Rock Samples Using Liquid Nitrogen under Tri-Axial Stresses
Authors: Yao B. , Wang L. , Patterson T. , Kneafsey T. J. , Yin X. , Wu Y. 
Published: February 2017

Abstract
Cryogenic fracturing is a waterless stimulation technology that uses cryogenic fluids to fracture unconventional oil and gas reservoirs, which, to date, are rarely investigated and poorly understood. This study aims to investigate the efficacy and feasibility of cryogenic fracturing technology in enhancing the permeability of unconventional reservoir rock analogs. Laboratory cryogenic fracturing experiments and finite difference modeling are integrated to reveal the processes and mechanism of cryogenic fluids on creating fractures in synthetic rock samples.
The 8-inch cubic rock samples were initially prepared by embedding eight tiny thermocouples on their diagonals to the depth of 4 inches, so real-time temperature distribution in the samples can be monitored during the experiments. Confined with true tri-axial stresses, liquid nitrogen was injected into the borehole to crack the synthetic rock samples at low pressure (~15 psi) and reservoir temperature (~85 °C) via a tubing-casing type wellhead. Before and after the liquid nitrogen stimulation, acoustic measurements and pressure decay tests were carried out to evaluate the fracture generation and permeability enhancements of the rock samples. The experimental processes were modeled using TOUGH2-EGS by integrating the Mogi–Coulomb failure criterion into the fracture generation module.
Comparison of pre- and post-stimulation pressure decay curves showed significant permeability enhancements of the synthetic rock samples after liquid nitrogen stimulation. Delay of acoustic signal arrivals measured on rock faces indicated that multiple fractures have been created inside the rock samples. Temperature profiles recorded during the liquid nitrogen stimulation mapped the temperature distribution through the rock samples. Rock properties were measured and input into the modified TOUGH2-EGS model to simulate the experiments, the results from modeling successfully reproduced the experimental results, in terms of temperature profiles, a general fracture morphology, and pressure decay curves.
Cryogenic stimulation is proved to be capable of generating fractures and enhancing the matrix permeability in the near-wellbore area at low injection pressure. The controlling factors in affecting the cryogenic fracturing effect are captured by the modified finite difference model, providing a useful tool for design and predication of field-scale applications.
An Improved Practical Solution for Modeling Single Phase Multi-Fractured Horizontal Well Performance
Authors: Behmanesh H. , Anderson D. M. , Thompson J. M. , Nakaska D. W. 
Published: February 2017

Abstract
Analytical modeling of multi-fractured horizontal well performance can be overly complex and cumbersome due to the use of Laplace space and pseudo-time. State-of-the-art analytical solutions are typically developed using Laplace space, which is not easily understood and often requires numerical inversion. Pseudo-time (for gas reservoirs) is iterative and has demonstrated issues with accuracy, particularly in stress-sensitive reservoirs. In this work, we present a new, practical semi-analytical model which provides a direct time domain solution using the succession of steady-states method without the need for pseudo-time.
The well-reservoir description used in our approach is based on the enhanced fracture region model introduced by Stalgarova and Mattar (2012). It is a composite system consisting of a stimulated (inner) region connected to a fracture and adjacent to an unstimulated (outer) region. Wattenbarger's bounded linear flow solution (1998) is utilized to account for linear flow contributions from both regions, in succession. The proportion of flow through time from the inner and outer regions is determined using a transient productivity index during transient flow and using material balance during boundary-dominated flow.
The accuracy of the model is evaluated by comparing its results to an equivalent numerical model, encompassing a wide variety of tight oil and gas descriptions with varying reservoir properties and operating conditions. For all cases studied, this model achieves either the same consistency with numerical simulation results, in comparison to its Laplace space counterpart. This new model is also more accurate for gas reservoirs with pressure-dependent rock and fluid properties. The associated nonlinearities are handled using a modified productivity index during transient flow, which is a function of the average reservoir pressure within the region of influence. This average pressure is traditionally calculated using a material balance performed over the area of investigation through an iterative procedure. In order to avoid such a procedure, an explicit relationship has been developed which correlates the average reservoir pressure to the initial reservoir pressure and the bottomhole flowing pressure. This new technique provides a simple engineering workflow and an alternative to numerical simulation for modeling complex fracture networks.
To the authors knowledge, this is the first analytical model which does not require an iterative approach to obtain its solution during transient flow. Since it is solved in the time domain (unlike models in Laplace space), it can be more easily implemented in a spreadsheet application. It is also more accurate, requires less calculation effort and can be extended to accommodate additional complexities, such as multiphase flow.
Coupling of Wellbore and Surface Facilities Models with Reservoir Simulation to Optimize Recovery of Liquids from Shale Reservoirs
Authors: Fragoso Alfonso , Trick Mona , Harding Thomas , Selvan Karthik , Aguilera Roberto 
Published: February 2017

Abstract
The objective of this paper is to couple wellbore and surface production facilities models with reservoir simulation for a shale reservoir that contains dry gas, condensate and oil in separate containers. The goal of this integration is to improve liquid recoveries by dry gas injection and gas recycling.
Methods published up to now to investigate possible means of improving recovery from shales have concentrated on laboratory work and the reservoir itself, but have ignored the surface and wellbore production facilities. The coupling of these facilities in the simulation work is critical, particularly in cases involving condensate and oil reservoirs, gas injection and recycling operations. This is so because a change in pressure in the reservoir is reflected almost immediately in a change in pressure in the wellbore and in the surface installations.
The development presented in this paper considers multi-stage hydraulically fractured horizontal wells. Dry gas is injected into zones that contain condensate and oil. Gas stripped from the condensate production is re-injected in the condensate zone in a recycling operation.
The study leads to the conclusion that liquid recoveries can be maximized by utilizing continuous and huff and puff gas injection schemes. In general, huff and puff injection provides better results in terms of production and economics. Molecular diffusion is found to play a crucial role in continuous gas injection operations. Conversely, the effect of this phenomenon is negligible in huff and puff gas injection. This research demonstrates that proper design of wellbore and surface installations, including for example downhole pumps and compressors, is important as they play a critical role in the performance of production and injection operations, and in maximizing recovery of liquids from shale reservoirs.
The novelty of the methodology developed in this paper is the coupling of models that handle surface facilities, wellbores, numerical simulation including oil, condensate and dry gas reservoirs, gas injection and gas-condensate recycling operations. Essentially the shale containers, wellbore and surface facilities are ‘talking’ to each other continuously. To the best of our knowledge this integration for shales has not been published previously in the literature.