bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: Copper‐Catalyzed C—O Coupling of Styrenes with N‐Hydroxyphthalimide Through Dihydroxylamination Reactions.
Authors: Xia Xiao‐Feng , Zhu Su‐Li , Zhang Danting 
Published: January 2016

AbstractThe title reaction is successfully performed starting from electron‐neutral or electron‐deficient styrene derivatives, but fails using cyclohexene or norbornene or styrenes with electron‐donating substituents.
ChemInform Abstract: Didecarboxylative Iron‐Catalyzed Bidirectional Aldolization Towards Diversity‐Oriented Ketodiol Synthesis.
Authors: Quintard Adrien , Rodriguez Jean 
Published: January 2016

AbstractThe scalable reaction between 1,3‐acetonedicarboxylic acid and alkyl aldehydes or benzaldehyde to keto‐3,3′‐diols represents a breakthrough from classical multistep procedures to an innovative one‐step approach.
ChemInform Abstract: Catalytic Transformation of Bio‐Derived Furans to Valuable Ketoacids and Diketones by Water‐Soluble Ruthenium Catalysts.
Authors: Gupta Kavita , Tyagi Deepika , Dwivedi Ambikesh D. , Mobin Shaikh M. , Singh Sanjay K. 
Published: January 2016

AbstractBio‐derived furans are efficiently and under moderate reaction conditions transformed into levulinic acid (III) and diketones [(II) and (IV)], resp., using recyclable and water‐soluble ruthenium(II) complexes as catalysts.
ChemInform Abstract: Design of an Indolylphosphine Ligand for Reductive Elimination‐Demanding Monoarylation of Acetone Using Aryl Chlorides.
Authors: Fu Wai Chung , So Chau Ming , Chow Wing Kin , Yuen On Ying , Kwong Fuk Yee 
Published: January 2016

AbstractThe title ligand in low loading applies to the reaction with aryl chlorides having different functional groups.
ChemInform Abstract: Cooperative Photo‐/Lewis Acid Catalyzed Tandem Intramolecular [3 + 2] Cross‐Cycloadditions of Cyclopropane 1,1‐Diesters with α,β‐Unsaturated Carbonyls for Medium‐Sized Carbocycles.
Authors: Wang Zhenjun , Chen Shuai , Ren Jun , Wang Zhongwen 
Published: January 2016

AbstractThe title reaction offers access to 8‐10‐membered carbocycle‐based oxabicyclo[n.2.1] skeletons.
ChemInform Abstract: Lewis Acid Catalyzed Formal Intramolecular [3 + 3] Cross‐Cycloaddition of Cyclopropane 1,1‐Diesters for Construction of Benzobicyclo[2.2.2]octane Skeletons.
Authors: Ma Weiwei , Fang Jie , Ren Jun , Wang Zhongwen 
Published: January 2016

AbstractThe reaction can be scaled up.
ChemInform Abstract: Direct Metal‐Free Synthesis of Diarylamines from 2‐Nitropropane via the Two Fold C—H Functionalization of Arenes.
Authors: Aksenov Alexander V. , Aksenov Nicolai A. , Orazova Naila A. , Aksenov Dmitrii A. , Dmitriev Maksim V. , Rubin Michael 
Published: January 2016

AbstractA novel cascade transformation conveniently affording symmetrical diarylamines possessing electron‐rich substituents from easily available precursors is investigated.
ChemInform Abstract: H2O2 in WEB: A Highly Efficient Catalyst System for the Dakin Reaction.
Authors: Saikia Bishwajit , Borah Parinita , Barua Nabin Chandra 
Published: January 2016

AbstractVarious phenols are synthesized in high yields via Dakin oxidation of substituted hydroxylated benzaldehydes using neat water extract of banana as an all‐in‐one mixture of solvent, catalyst, ligand, base, additive, promoter etc.
ChemInform Abstract: Four‐Component Electrophilic Difunctionalization of Olefins Using Sulfonic Acids, Cyclic Ethers, and NBS.
Authors: Sohail Muhammad , Khan Muhammad , Zhang Yixin , Peng Chang , Chen Qin , Zhao Zongbao K. 
Published: January 2016

AbstractThe novel, highly regio‐ and diastereoselective four‐component reaction affords sulfonate ester derivatives.
ChemInform Abstract: One‐Pot Two‐Step Cycloaddition Reaction for Convenient Synthesis of Polycyclic Spirooxindole‐Fused [1,3]Oxazines.
Authors: Sun Jing , Gong Hui , Yan Chaoguo 
Published: January 2016

AbstractThe novel spirooxindoline fused [1,3]oxazines (V) and (VI) are efficiently synthesized by an one‐pot two‐step domino reaction, which involves the sequential formation of a Huisgens 1,4‐dipole, 1,4‐dipolar cycloaddition and a Diels—Alder reaction.
ChemInform Abstract: Divergent Cyclization Reactions of Morita—Baylis—Hillman Carbonates of 2‐Cyclohexenone and Isatylidene Malononitriles.
Authors: Peng Jing , Ran Guang‐Yao , Du Wei , Chen Ying‐Chun 
Published: January 2016

AbstractZwitterionic dienolates generated from carbonates (II) in the presence of the corresponding organocatalyst undergo divergent cyclization reactions with isatylidene malononitriles.
ChemInform Abstract: Synthesis of 4‐Arylidenepyrazolones by a Gold‐Catalyzed Cyclization/Arylidene Group Transfer Cascade of N‐Propioloyl Hydrazones.
Authors: Ding Zong‐Cang , Tang Hai‐Tao , Li Ren‐Hao , Ju Lu‐Chuan , Zhan Zhuang‐Ping 
Published: January 2016

AbstractThis approach towards preparation of arylidenepyrazolone derivatives relies on a gold‐catalyzed cyclization/1,3‐migration cascade.
ChemInform Abstract: Copper‐Catalyzed Inter‐ and Intramolecular C—N Bond Formation: Synthesis of Benzimidazole‐Fused Heterocycles.
Authors: Rasheed Sk. , Rao D. Nageswar , Das Parthasarathi 
Published: January 2016

AbstractThe reaction cascade combines a Chan—Lam type coupling and a subsequent Ullmann type coupling.
ChemInform Abstract: Clean Synthesis of N‐Pyrrolyl Azoles by Metal‐Free Oxidative Cross‐Coupling Using Recyclable Hypervalent Iodine Reagent.
Authors: Morimoto Koji , Ogawa Ryosuke , Koseki Daichi , Takahashi Yusuke , Dohi Toshifumi , Kita Yasuyuki 
Published: January 2016

AbstractN‐Functionalized azoles are easily synthesized by an oxidative coupling reaction using the recyclable reagent TDIPA under metal‐free and mild reaction conditions.
ChemInform Abstract: Diastereoselective Synthesis of Angularly Fused Pyranochromenes.
Authors: Sarmah Barnali , Baishya Gakul , Hazarika Nabajyoti , Das Pranab Jyoti 
Published: January 2016

Abstract2‐Hydroxy‐6‐methylhept‐5‐ene (I) reacts with salicylaldehydes (II), (IV), and (VI) under TfOH‐catalysis to the pyrano[3.2‐c]chromenes (III), (V), and (VII) in good yields and with high diastereoselectivities.
ChemInform Abstract: RhI/RhIII Catalyst‐Controlled Divergent Aryl/Heteroaryl C—H Bond Functionalization of Picolinamides with Alkynes.
Authors: Martinez Angel Manu , Echavarren Javier , Alonso Ines , Rodriguez Nuria , Gomez Arrayas Ramon , Carretero Juan C. 
Published: January 2016

AbstractWhen Rh(I) catalyst is used, the C—H bonds of aryl groups of picolinamides [e.g. (I)] are functionalized to give ortho‐olefinated benzylamines [e.g. (II)] or phenethylamines [e.g. (XIII)].
ChemInform Abstract: Light Triggered Addition/Annulation of 2‐Isocyanobiphenyls Toward 6‐Trifluoromethyl‐phenanthridines under Photocatalyst‐Free Conditions.
Authors: Tang Xiangyang , Song Shuang , Liu Cuibo , Zhu Rongjiao , Zhang Bin 
Published: January 2016

AbstractA simple and environmental benign direct light‐initiated one‐pot radical addition/annulation of 2‐isocyanobiphenyls is presented.
ChemInform Abstract: Sodium Salts of Anionic Chiral Cobalt(III) Complexes as Catalysts of the Enantioselective Povarov Reaction.
Authors: Yu Jie , Jiang Hua‐Jie , Zhou Ya , Luo Shi‐Wei , Gong Liu‐Zhu 
Published: January 2016

AbstractRing‐fused tetrahydroquinolines with up to three contiguous stereogenic centers are obtained in high yields, excellent diastereoselectivities, and high enantioselectivities, starting either from imines or aldehydes.
ChemInform Abstract: Construction of Benzo‐Fused Indolizines, Pyrrolo[1,2‐a]quinolines via Alkyne—Carbonyl Metathesis.
Authors: Nayak Maloy , Kim Ikyon 
Published: January 2016

AbstractSequential Sonogashira coupling of 2‐(2‐formylpyrrolyl)iodoarenes with terminal alkynes followed by intramolecular alkyne‐carbonyl metathesis reaction yields the title compounds.
ChemInform Abstract: Gold‐Catalyzed Formal [4π + 2π]‐Cycloadditions of Propiolate Derivatives with Unactivated Nitriles.
Authors: Karad Somnath Narayan , Chung Wei‐Kang , Liu Rai‐Shung 
Published: January 2016

AbstractThe title cycloadditions afford oxazinones [e.g. (III)] which are not easily accessible by using conventional methods.
ChemInform Abstract: Gold(I)‐Catalyzed Cycloisomerization of Vinylidenecyclopropane‐enes via Carbene or Non‐Carbene Processes.
Authors: Li De‐Yao , Wei Yin , Marek Ilan , Tang Xiang‐Ying , Shi Min 
Published: January 2016

AbstractThe aromatic ring tethered vinylidenecyclopropane‐enes with less electron‐rich ortho‐substituents [e.g. (I)], isomerize to fused heterocycle [e.g. (II)] via a gold carbene intermediate generated from a rearrangement of vinylidenecyclopropane moiety.
ChemInform Abstract: Catalytic Asymmetric Conjugate Addition of α‐Fluoro β‐Ketophosphonates to Nitroalkenes in the Presence of Nickel Complexes.
Authors: Sung Hyun Ji , Mang Joo Yang , Kim Dae Young 
Published: January 2016

AbstractThe reaction of α‐fluoro β‐ketophosphonates (I) with nitroalkenes [(II) or (IV), resp.] affords the corresponding Michael adducts [(III) or (V), resp.] in high yields, high diastereoselectivities and excellent enantioselectivities.
ChemInform Abstract: Pestalotriols A and B, New Spiro[2.5]octane Derivatives from the Endophytic Fungus Pestalotiopsis fici.
Authors: Liu Ling , Zhao Chen , Li Li , Guo Liangdong , Che Yongsheng 
Published: January 2016

AbstractPestalotriols A and B are screened for their cytotoxicity against HeLa, A549, T24, and MCF‐7 human cancer cell lines.
ChemInform Abstract: Non‐Conjugated Polymer Dots with Crosslink‐Enhanced Emission in the Absence of Fluorophore Units
Authors: Zhu Shoujun , Song Yubin , Shao Jieren , Zhao Xiaohuan , Yang Bai 
Published: January 2016

AbstractReview: [synthetic strategies, optical properties, and potential applications of non‐conjugated polymer dots in biology‐related fields; 47 refs.
Numerische Untersuchungen der hydrodynamischen Dispersion in Kugelschüttungen aus porösen Mikropartikeln
Authors: Barthelmie Eugenia , Sdrenka Sebastian , Ma Yong , Brenner Gunther 
Published: January 2016

AbstractIn der vorliegenden Arbeit wird der Zusammenhang zwischen der Morphologie von Kugelschüttungen aus porösen Mikropartikeln und der hydrodynamischen Dispersion untersucht. Der Ansatz basiert auf der skalenauflösenden Berechnung der Navier‐Stokes‐Gleichungen mittels der Finite‐Volumen‐Methode und auf der lokalen Volumenmittelung zur Bestimmung der effektiven Transportgrößen. Die Ergebnisse zeigen, dass mit der Einführung von Transportporen in einer Kugelpackung die Dispersion deutlich gesteigert werden kann.
Biomechanical model for computing deformations for whole‐body image registration: A meshless approach
Authors: Li Mao , Miller Karol , Joldes Grand Roman , Kikinis Ron , Wittek Adam 
Published: January 2016

SummaryPatient‐specific biomechanical models have been advocated as a tool for predicting deformations of soft body organs/tissue for medical image registration (aligning two sets of images) when differences between the images are large. However, complex and irregular geometry of the body organs makes generation of patient‐specific biomechanical models very time‐consuming. Meshless discretisation has been proposed to solve this challenge. However, applications so far have been limited to 2D models and computing single organ deformations. In this study, 3D comprehensive patient‐specific nonlinear biomechanical models implemented using meshless Total Lagrangian explicit dynamics algorithms are applied to predict a 3D deformation field for whole‐body image registration. Unlike a conventional approach that requires dividing (segmenting) the image into non‐overlapping constituents representing different organs/tissues, the mechanical properties are assigned using the fuzzy c‐means algorithm without the image segmentation. Verification indicates that the deformations predicted using the proposed meshless approach are for practical purposes the same as those obtained using the previously validated finite element models. To quantitatively evaluate the accuracy of the predicted deformations, we determined the spatial misalignment between the registered (i.e. source images warped using the predicted deformations) and target images by computing the edge‐based Hausdorff distance. The Hausdorff distance‐based evaluation determines that our meshless models led to successful registration of the vast majority of the image features. Copyright © 2016 John Wiley & Sons, Ltd.
Multidimensional Polyaniline/Reduced Graphene Oxide/Silica Nanocomposite for Efficient Supercapacitor Electrodes
Authors: Kim Jihoo , Kim Minkyu , Cho Sunghun , Yoon Chang‐Min , Lee Choonghyeon , Ryu Jaehoon , Jang Jyongsik 
Published: January 2016

AbstractThe combination of reduced graphene oxide (RGO) with silica nanoparticles as shaping agents results in an enhanced surface area of RGO by the inhibition of π–π stacking between the RGO sheets, leading to enhanced electrochemical properties of the polyaniline/RGO/silica nanocomposite. The nanocomposite exhibits a multidimensional structure, in which urchin‐like polyaniline nanofibers are grown on the RGO ball and the surface of the silica nanoparticle is entirely sealed with the polyaniline and RGO sheets. The nanocomposite also demonstrates efficient electrochemical properties due to the enhanced surface area, electrical conductivity, and synergetic effects between RGO and polyaniline. This method could pave the way to the development of advanced devices for energy‐storage systems.
Kinetic Passivation Effect of Localized Differential Aeration on Brass
Authors: Kuznetsov Volodymyr , Estrada‐Vargas Arturo , Maljusch Artjom , Berkes Balázs B. , Bandarenka Aliaksandr S. , Souto Ricardo M. , Schuhmann Wolfgang 
Published: January 2016

AbstractInvited for this month's cover are collaborators from Ruhr University Bochum (Germany), Technical University Munich (Germany), and University of La Laguna, Tenerife (Spain). The cover picture shows the passivation effect of a liquid in a brass tube in the presence of oxygen in the gas phase. Read the full text of the article at 10.1002/cplu.201500398.
Enhanced Organic Solar Cell Stability through the Effective Blocking of Oxygen Diffusion using a Self‐Passivating Metal Electrode
Authors: Lee Hansol , Jo Sae Byeok , Lee Hyo Chan , Kim Min , Sin Dong Hun , Ko Hyomin , Cho Kilwon 
Published: January 2016

AbstractA new and simple strategy for enhancing the stability of organic solar cells (OSCs) was developed by using self‐passivating metal top electrodes. Systematic investigations on O2 permeability of Al top electrodes revealed that the main pathways for oxidation‐induced degradation could be greatly suppressed by simply controlling the nanoscale morphology of the Al electrode. The population of nanoscale pinholes among Al grains, which critically decided the diffusion of O2 molecules toward the Al–organic interfaces that are vulnerable to oxidation, was successfully regulated by rapidly depositing Al or promoting lateral growth among the Al grains, accompanied by increasing the deposition thickness. Our observations suggested that the stability of OSCs with conventional architectures might be greatly enhanced simply by controlling the fabrication conditions of the Al top electrode, without the aid of additional secondary treatments.
Development and Application of a Sensor Based on Carbonaceous Materials and Cobalt Phthalocyanine Composite for Electrochemical Determination of Uric Acid
Authors: de Fátima Giarola Juliana , César Pereira Arnaldo 
Published: January 2016

AbstractIn the present paper a voltammetric sensor based on glassy carbon electrode (GCE) and cobalt phthalocyanine (CoPc)/multiwalled carbon nanotube (MWCNT) composite has been successfully prepared for uric acid (UA) determination in real samples. The electrochemical behavior of UA at the GCE‐CoPc/MWCNT has been evaluated by employing cyclic voltammetry. The charge transfer coefficient, α, and the charge transfer rate constant, κs, for electron transfer between CoPc/MWCNT and GCE were calculated as 0.49 and 19.5±0.51 s−1, respectively. Under optimized conditions (pH 7.0 in 0.10 mol L−1 phosphate buffer) the best technique was the square wave voltammetry and responds linearly to UA from 0.2 up to 1.0 mmol L−1 (r=0.997) and 1.25 up to 4.0 mmol L−1 (r=0.991) with limits of detection and quantification of 0.26 and 0.86 mmol L−1, respectively. The developed method was successfully applied for UA determination in real samples of human urine. The modified electrode exhibits sensitive and stable responses and does not show interferences in presence of dopamine and ascorbic acid.
Prussian Blue and Chitosan Modified Carbon Cloth Electrode as a High Performance Sensor of Ascorbic Acid
Authors: Yue Pengwei , Tricard Simon , He Sifa , Wang Ning , Zhao Jihua , Fang Jian , Shen Weiguo 
Published: January 2016

AbstractThe modification of carbon cloth (CC) with Prussian blue (PB) and chitosan (CS) leads to the elaboration of a composite electrode (PB/CS/CC), employed to electrocatalyze the oxidation of ascorbic acid (AA). This electrode exhibits great performances towards the AA detection, thanks to the good conductivity of CC and the efficient catalytic properties of PB. The modified electrode shows a rapid response of less than 2 s, a very high sensitivity of 1.64 A ⋅ M−1 and a good resistance towards common interferences. Its linear range goes from 3×10−7 M to 3×10−4 M (R2=0.993), with a detection limit (S/N=3) of 2.50×10−7 M. Finally, such electrode can detect AA in commercial vitamin C; it is thus a good candidate as a simple and convenient sensor for general applications.
Anticipation, Tax Avoidance, and the Price Elasticity of Gasoline Demand
Authors: Coglianese John , Davis Lucas W. , Kilian Lutz , Stock James H. 
Published: January 2016

SummaryLeast‐squares estimates of the response of gasoline consumption to a change in the gasoline price are biased toward zero, given the endogeneity of gasoline prices. A seemingly natural solution to this problem is to instrument for gasoline prices using gasoline taxes, but this approach tends to yield implausibly large price elasticities. We demonstrate that anticipatory behavior provides an important explanation for this result. Gasoline buyers increase purchases before tax increases and delay purchases before tax decreases, rendering the tax instrument endogenous. Including suitable leads and lags in the regression restores the validity of the IV estimator, resulting in much lower elasticity estimates. Copyright © 2016 John Wiley & Sons, Ltd.
Ultrasound of paediatric appendicitis and its secondary sonographic signs: providing a more meaningful finding
Authors: Reddan Tristan , Corness Jonathan , Mengersen Kerrie , Harden Fiona 
Published: January 2016

AbstractSonography is an important clinical tool in diagnosing appendicitis in children as it can obviate both exposure to potentially harmful ionising radiation from computed tomography scans and the need for unnecessary appendicectomies. This review examines the diagnostic accuracy of ultrasound in the identification of acute appendicitis, with a particular focus on the the utility of secondary sonographic signs as an adjunct or corollary to traditionally examined criteria. These secondary signs can be important in cases where the appendix cannot be identified with ultrasound and a more meaningful finding may be made by incorporating the presence or absence of secondary sonographic signs. There is evidence that integrating these secondary signs into the final ultrasound diagnosis can improve the utility of ultrasound in cases where appendicitis is expected, though there remains some conjecture about whether they play a more important role in negative or positive prediction in the absence of an identifiable appendix.
A comparison of three different VMAT techniques for the delivery of lung stereotactic ablative radiation therapy
Authors: Fitzgerald Rhys , Owen Rebecca , Hargrave Catriona , Pryor David , Barry Tamara , Lehman Margot , Bernard Anne , Mai Tao , Seshadri Venkatakrishnan , Fielding Andrew 
Published: January 2016

AbstractIntroductionThe purpose of this study was to investigate coplanar and non‐coplanar volumetric modulated arc therapy (VMAT) delivery techniques for stereotactic ablative radiation therapy (SABR) to the lung.MethodsFor ten patients who had already completed a course of radiation therapy for early stage lung cancer, three new SABR treatment plans were created using (1) a coplanar full arc (FA) technique, (2) a coplanar partial arc technique (PA) and (3) a non‐coplanar technique utilising three partial arcs (NCA). These plans were evaluated using planning target volume (PTV) coverage, dose to organs at risk, and high and intermediate dose constraints as incorporated by radiation therapy oncology group (RTOG) 1021.ResultsWhen the FA and PA techniques were compared to the NCA technique, on average the PTV coverage (V54Gy) was similar (P = 0.15); FA (95.1%), PA (95.11%) and NCA (95.71%). The NCA resulted in a better conformity index (CI) of the prescription dose (0.89) when compared to the FA technique (0.88, P = 0.23) and the PA technique (0.83, P = 0.06). The NCA technique improved the intermediate dose constraints with a statistically significant difference for the D2cm and R50% when compared with the FA (P < 0.03 and <0.0001) and PA (P < 0.04 and <0.0001) techniques. The NCA technique reduced the maximum spinal cord dose by 2.72 and 4.2 Gy when compared to the PA and FA techniques respectively. Mean lung doses were 4.09, 4.31 and 3.98 Gy for the FA, PA and NCA techniques respectively.ConclusionThe NCA VMAT technique provided the highest compliance to RTOG 1021 when compared to coplanar techniques for lung SABR. However, single FA coplanar VMAT was suitable for 70% of patients when minor deviations to both the intermediate dose and organ at risk (OAR) constraints were accepted.
Evaluation of P‐glycoprotein (Pgp) expression in human osteosarcoma by high‐throughput tissue microarray
Authors: Gao Yan , Liao Yunfei , Shen Jacson K. , Feng Yong , Choy Edwin , Cote Gregory , Harmon David , Mankin Henry J. , Hornicek Francis J. , Duan Zhenfeng 
Published: January 2016

ABSTRACTSurvival of osteosarcoma patients is currently limited by the development of metastases and multidrug resistance (MDR). A well‐established cause of MDR involves overexpression of P‐glycoprotein (Pgp) in tumor cells. However, some discrepancies still exist as to the clinical significance of Pgp in osteosarcoma. We sought to elucidate further whether the Pgp expression correlated with clinical behavior in a series of patients with osteosarcoma via high‐throughput tissue microarray (TMA) analysis. Immunohistochemical analysis of Pgp expression in a TMA of 114 specimens with a retrospective review of 70 osteosarcoma patients admitted to the Massachusetts General Hospital (MGH) was performed. High Pgp expression was correlated with metastasis development and poor response to pre‐operative chemotherapy in osteosarcoma patients. Eighteen of the fifty‐seven patients initially admitted with primary osteosarcoma showed high Pgp expression. Among these 18 patients with high Pgp expression, 13 of 18 (72%) patients eventually developed metastases. There was no significant clinical relevance between Pgp expression and osteosarcoma survival. These results support that high expression of Pgp is important, but cannot be assigned as, an individual predictor in the development of human osteosarcoma. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:1606–1612, 2016.