bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term outcomes of epilepsy surgery in 85 pediatric patients followed up for over 10 years: a retrospective survey
Authors: Hosoyama Hiroshi , Matsuda Kazumi , Mihara Tadahiro , Usui Naotaka , Baba Koichi , Inoue Yushi , Tottori Takayasu , Otsubo Toshiaki , Kashida Yumi , Iida Koji , Hirano Hirofumi , Hanaya Ryosuke , Arita Kazunori 
Published: March 2017

OBJECTIVEThe aim of this study was to investigate the treatment outcomes and social engagement of patients who had undergone pediatric epilepsy surgery more than 10 years earlier.METHODSBetween 1983 and 2005, 110 patients younger than 16 years underwent epilepsy surgery at the National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders. The authors sent a questionnaire to 103 patients who had undergone follow-up for more than 10 years after surgery; 85 patients (82.5%) responded. The survey contained 4 categories: seizure outcome, use of antiepileptic drugs, social participation, and general satisfaction with the surgical treatment (resection of the epileptic focus, including 4 hemispherectomies). The mean patient age at the time of surgery was 9.8 ± 4.2 (SD) years, and the mean duration of postoperative follow-up was 15.4 ± 5.0 years. Of the 85 patients, 79 (92.9%) presented with a lesional pathology, such as medial temporal sclerosis, developmental/neoplastic lesions, focal cortical dysplasia, and gliosis in a single lobe.RESULTSFor 65 of the 85 responders (76.5%), the outcome was recorded as Engel Class I (including 15 [93.8%] of 16 patients with medial temporal sclerosis, 20 [80.0%] of 25 with developmental/neoplastic lesions, and 27 [73.0%] of 37 with focal cortical dysplasia). Of these, 29 (44.6%) were not taking antiepileptic drugs at the time of our survey, 29 (44.6%) held full-time jobs, and 33 of 59 patients (55.9%) eligible to drive had a driver's license. Among 73 patients who reported their degree of satisfaction, 58 (79.5%) were very satisfied with the treatment outcome.CONCLUSIONSThe seizure outcome in patients who underwent resective surgery in childhood and underwent followup for more than 10 years was good. Of 85 respondents, 65 (76.5%) were classified in Engel Class I. The degree of social engagement was relatively high, and the satisfaction level with the treatment outcome was also high. From the perspective of seizure control and social adaptation, resective surgery yielded longitudinal benefits in children with intractable epilepsy, especially those with a lesional pathology in a single lobe.
Sulfur Hazes in Giant Exoplanet Atmospheres: Impacts on Reflected Light Spectra
Authors: Gao Peter , Marley Mark S. , Zahnle Kevin , Robinson Tyler D. , Lewis Nikole K. 
Published: March 2017

Abstract
Recent work has shown that sulfur hazes may arise in the atmospheres of some giant exoplanets, due to the photolysis of H2S. We investigate the impact such a haze would have on an exoplanet’s geometric albedo spectrum and how it may affect the direct imaging results of the Wide Field Infrared Survey Telescope (WFIRST), a planned NASA space telescope. For temperate (250 K < T
eq < 700 K) Jupiter-mass planets, photochemical destruction of H2S results in the production of ∼1 ppmv of S8 between 100 and 0.1 mbar, which, if cool enough, will condense to form a haze. Nominal haze masses are found to drastically alter a planet’s geometric albedo spectrum: whereas a clear atmosphere is dark at wavelengths between 0.5 and 1 μm, due to molecular absorption, the addition of a sulfur haze boosts the albedo there to ∼0.7, due to scattering. Strong absorption by the haze shortward of 0.4 μm results in albedos <0.1, in contrast to the high albedos produced by Rayleigh scattering in a clear atmosphere. As a result, the color of the planet shifts from blue to orange. The existence of a sulfur haze masks the molecular signatures of methane and water, thereby complicating the characterization of atmospheric composition. Detection of such a haze by WFIRST is possible, though discriminating between a sulfur haze and any other highly reflective, high-altitude scatterer will require observations shortward of 0.4 μm, which is currently beyond WFIRST’s design.
Stellar and Planetary Parameters for K2's Late-type Dwarf Systems from C1 to C5
Authors: Martinez Arturo O. , Crossfield Ian J. M. , Schlieder Joshua E. , Dressing Courtney D. , Obermeier Christian , Livingston John , Ciceri Simona , Peacock Sarah , Beichman Charles A. , Lépine Sébastien , Aller Kimberly M. , Chance Quadry A. , Petigura Erik A. , Howard Andrew W. , Werner Michael W. 
Published: March 2017

Abstract
The NASA K2 mission uses photometry to find planets transiting stars of various types. M dwarfs are of high interest since they host more short-period planets than any other type of main-sequence star and transiting planets around M dwarfs have deeper transits compared to other main-sequence stars. In this paper, we present stellar parameters from K and M dwarfs hosting transiting planet candidates discovered by our team. Using the SOFI spectrograph on the European Southern Observatory’s New Technology Telescope, we obtained R ≈ 1000 J-, H-, and K-band (0.95–2.52 μm) spectra of 34 late-type K2 planet and candidate planet host systems and 12 bright K4–M5 dwarfs with interferometrically measured radii and effective temperatures. Out of our 34 late-type K2 targets, we identify 27 of these stars as M dwarfs. We measure equivalent widths of spectral features, derive calibration relations using stars with interferometric measurements, and estimate stellar radii, effective temperatures, masses, and luminosities for the K2 planet hosts. Our calibrations provide radii and temperatures with median uncertainties of 0.059 R
⊙ (16.09%) and 160 K (4.33%), respectively. We then reassess the radii and equilibrium temperatures of known and candidate planets based on our spectroscopically derived stellar parameters. Since a planet’s radius and equilibrium temperature depend on the parameters of its host star, our study provides more precise planetary parameters for planets and candidates orbiting late-type stars observed with K2. We find a median planet radius and an equilibrium temperature of approximately 3 R
⊕ and 500 K, respectively, with several systems (K2-18b and K2-72e) receiving near-Earth-like levels of incident irradiation.
Evolution of Star Clusters in Time-variable Tidal Fields
Authors: Mamikonyan Ernest N. , McMillan Stephen L. W. , Vesperini Enrico , Low Mordecai-Mark Mac 
Published: March 2017

Abstract
Strong tidal forces can dominate star cluster evolution in merging galaxies, determining their mass-loss rates and lifetimes. In order to model this evolution, we have developed a second-order accurate numerical method for integrating a star cluster in an arbitrary time-variable tidal field. We extend the Kira
N-body integrator to handle these external fields. We obtain realistic tidal histories from a galaxy merger simulation including sink particles, which we interpret as young star clusters. Coupling these tidal accelerations to N-body models of isolated clusters, we perform detailed dynamical studies. This generalizes the formalism previously used to explore the dynamical effects of the galactic tidal field on clusters in circular orbits. We find that, in contrast to previous studies that considered only stellar and dark matter dynamics, tidal interactions between clusters and dense gas in the galactic disk can significantly influence cluster mass loss and lifetimes. Using our models, we develop an effective semianalytic model that can be used for fast estimation of cluster mass loss in a galactic tidal field and to study the evolution of the globular cluster mass function in isolated and merging galaxies.
A Catalog Sample of Low-mass Galaxies Observed in X-Rays with Central Candidate Black Holes
Authors: Nucita A. A. , Manni L. , Paolis F. De , Giordano M. , Ingrosso G. 
Published: March 2017

Abstract
We present a sample of X-ray-selected candidate black holes in 51 low-mass galaxies with z ≤ 0.055 and masses up to 1010
M
⊙ obtained by cross-correlating the NASA-SLOAN Atlas with the 3XMM catalog. We have also searched in the available catalogs for radio counterparts of the black hole candidates and find that 19 of the previously selected sources also have a radio counterpart. Our results show that about 37% of the galaxies of our sample host an X-ray source (associated with a radio counterpart) spatially coincident with the galaxy center, in agreement with other recent works. For these nuclear sources, the X-ray/radio fundamental plane relation allows one to estimate the mass of the (central) candidate black holes, which are in the range of 104–2 × 108
M
⊙ (with a median value of ≃3 × 107
M
⊙ and eight candidates having masses below 107
M
⊙). This result, while suggesting that X-ray emitting black holes in low-mass galaxies may have had a key role in the evolution of such systems, makes it even more urgent to explain how such massive objects formed in galaxies. Of course, dedicated follow-up observations both in the X-ray and radio bands, as well as in the optical, are necessary in order to confirm our results.
Entre blessures de guerre et guerre des blessures : la « balle humanitaire » en débat en Europe et au Japon, 1890-1905
Authors: Daimaru Ken 
Published: March 2017

L’histoire de la « balle humanitaire » permet de poser un nouveau regard sur les transformations de la médecine militaire et de la représentation des blessures de guerre à l’orée du XX e siècle. À partir d’une approche croisée, en Europe et au Japon, du débat médical sur l’évolution des propriétés balistiques des nouvelles armes à feu, ce texte analyse l’émergence et le développement d’un groupe de médecins experts en « balistique lésionnelle ». Ces professionnels participent, au sein des appareils militaires, à l’anticipation des atteintes corporelles et à l’optimisation des effets du feu, dans un but à la fois curatif et vulnérant. Ainsi les médecins collaborent aux dégâts qu’ils contribuent par vocation à réparer. Nous explorons dans cet article le caractère problématique du concept de « balle humanitaire » et l’appropriation par les acteurs médicaux européens et japonais des dispositifs militaires produits dans le « monde civilisé ». Enfin, nous discutons de la mise en débat public de ces questions, autour de la controverse des balles dum-dum et de la « guerre des blessures ».
Aux fondements introuvables de l’État-providence : la loi du 9 avril 1898 à l’épreuve de la Grande Guerre
Authors: Viet Vincent 
Published: March 2017

La loi du 9 avril 1898 est souvent présentée comme le socle fondateur de la législation des accidents du travail, qui aurait défié le temps moyennant des aménagements de pure commodité. Sa pérennisation justifierait qu’on l’étudie isolément. En réalité, ce texte a influencé d’autres législations et produit des excroissances juridiques, garantes de sa longévité. La Grande Guerre en offre une illustration, qui a vu cette loi devenir un élément clé du statut de la main-d’œuvre mobilisée ; servir de ressource juridique au calcul des pensions et gratifications militaires ; enfin, s’hybrider avec l’assistance militaire pour assurer l’indemnisation des mutilés de guerre accidentés du travail. D’où l’intérêt de revenir sur les relations entre la réparation civile des accidents du travail et la réparation militaire des infirmités et des maladies de guerre, qui permettent de comprendre pourquoi l’État-providence n’est pas né de cette loi ni, curieusement, des décombres de la guerre.
Nathalie St/G-R-Anger et l’inquiétante étrangeté de la maison des femmes
Authors: Meyer zum Wischen Michael 
Published: March 2017

En 1972, Marguerite Duras écrivit le scénario d’un film intitulé Nathalie Granger . La même année, Jacques Lacan commença son séminaire novateur Encore sur la sexualité féminine. Il est frappant que Marguerite Duras, qui tourna le film dans sa propre maison, en vint à la qualifier en employant des mots comme « étrange » et « inquiétante ». Cet article essaie, en se servant du scénario de Marguerite Duras, d’approfondir le concept freudien d’« inquiétante étrangeté » eu égard aux élaborations du dernier Lacan. Quant aux femmes, Duras parle « de cette fonction, submergeante, d’enfouissement du discours en un lieu où il s’annule, se tait , se supprime ». On peut comparer cette phrase à une énonciation de Lacan dans Encore où il dit : « S’il y en avait une autre, mais il n’y en a pas d’autre que la jouissance phallique – sauf celle sur laquelle la femme ne souffle mot, peut-être parce qu’elle ne la connaît pas, celle qui la fait pas-toute. »
Perversion et psychose I Leurs différences et leurs interférences dans l’œuvre de Freud
Authors: Kaltenbeck Franz 
Published: March 2017

Les trois structures cliniques – névroses, psychoses et perversions – ne se limitent pas à des tableaux cliniques. Elles posent plutôt des questions existentielles aux êtres parlants qui y sont pris. Ces structures ne se confondent pas. Mais elles peuvent interférer l’une dans l’autre. La perversion peut avoir des répercussions à un moment donné de la vie d’un(e) psychotique, sans qu’on puisse minimiser son incident à un « trait de perversion ». Ce fait observable nous a amené à relire Freud pour savoir ce qui, dans sa théorie, différencie la perversion de la psychose et ce qui les rapproche.
Molecular genetic evaluation of <em>Cichorium endivia</em> L. as an anticancer agent against colorectal cancer
Authors: Hafez Elsayed E , Badr Effat , Mabrouk Yasser , El-Seehy Mohammed , Aggag Sarah 
Published: March 2017

<p>Medicinal plants confer protective effects against a wide range of cancers including colon cancer. <em>Cichorium endivia</em> L. has many biological activities and functions, such as anti-inflammation and hepatoprotective effects. This activity is mainly due to its high levels of antioxidant compounds. The effect of cichorium extract and fluorouracil (5-FU) against colorectal cancer (CRC) induced by 1, 2- Dimethyl hydrazine (DMH) was examined in male albino mice. Where, different doses of cichorium extract (200, 400 and 600 mg/kg body weight) were investigated to determine the significant effective dose against colorectal cancer using differential display-PCR (DD-PCR), DNA sequencing, histopathological and cytological techniques. The results showed that the cichorium extract dose 200 mg/kg body weight was the best one compared to the others (400 and 600 mg/kg body weight). This finding could be a powerful therapeutic against colorectal cancer.</p><p> </p>
Insights into aerosol chemistry during the 2015 China Victory Day parade: results from simultaneous measurements at ground level and 260 m in Beijing
Authors: Zhao Jian , Du Wei , Zhang Yingjie , Wang Qingqing , Chen Chen , Xu Weiqi , Han Tingting , Wang Yuying , Fu Pingqing , Wang Zifa , Li Zhanqing , Sun Yele 
Published: March 2017

Abstract. Strict emission controls were implemented in Beijing and adjacent provinces to ensure good air quality during the 2015 China Victory Day parade. Here, we conducted synchronous measurements of submicron aerosols (PM1) at ground level and 260 m on a meteorological tower by using a high-resolution aerosol mass spectrometer and an aerosol chemical speciation monitor, respectively, in Beijing from 22 August to 30 September. Our results showed that the average PM1 concentrations are 19.3 and 14.8 µg m−3 at ground level and 260 m, respectively, during the control period (20 August–3 September), which are 57 and 50 % lower than those after the control period (4–30 September). Organic aerosols (OAs) dominated PM1 during the control period at both ground level and 260 m (55 and 53 %, respectively), while their contribution showed substantial decreases (∼  40 %) associated with an increase in secondary inorganic aerosols (SIAs) after the parade, indicating a larger impact of emission controls on SIA than OA. Positive matrix factorization of OA further illustrated that primary OA (POA) showed similar decreases as secondary OA (SOA) at both ground level (40 % vs. 42 %) and 260 m (35 % vs. 36 %). However, we also observed significant changes in SOA composition at ground level. While the more oxidized SOA showed a large decrease by 75 %, the less oxidized SOA was comparable during (5.6 µg m−3) and after the control periods (6.5 µg m−3). Our results demonstrated that the changes in meteorological conditions and PM loadings have affected SOA formation mechanisms, and the photochemical production of fresh SOA was more important during the control period. By isolating the influences of meteorological conditions and footprint regions in polluted episodes, we found that regional emission controls on average reduced PM levels by 44–45 %, and the reductions were close among SIA, SOA and POA at 260 m, whereas primary species showed relatively more reductions (55–67 %) than secondary aerosol species (33–44 %) at ground level.
SMART – Sediment Mitigation Actions for the River Rother, UK
Authors: Evans Jennine L. , Foster Ian , Boardman John , Holmes Naomi 
Published: March 2017

Abstract. The River Rother, West Sussex, is suffering from excess sediment which is smothering the river bed gravels. This is thought to be exacerbating issues of pollution and degradation of ecosystems. This project aims to identify the severity, extent, possible causes and potential mitigation options available to reduce these pressures on the river. Data have been collected from ten sites to investigate the amount of sediment stored in the river bed gravels and cores obtained from four small reservoirs to establish rates of sedimentation and contribute to the construction of a temporal sediment budget over the last 50–100 years. Evidence suggests that tributary streams have more stored sediment per m2 upstream of their confluence with the River Rother compared to the Rother itself. Reservoir core data indicate that sediment has accumulated more rapidly in the small reservoirs surrounded by mixed agricultural land compared to one surrounded by ancient woodland. These are preliminary results and work is continuing.
Bedload transport monitoring with acoustic sensors in the Swiss Albula mountain river
Authors: Rickenmann Dieter , Antoniazza Gilles , Wyss Carlos R. , Fritschi Bruno , Boss Stefan 
Published: March 2017

Abstract. Bedload transport measurements with acoustic sensors were obtained during summer 2015 in the Albula River in Switzerland. An impact plate measuring system was used with geophone and accelerometer sensors. This system provides indirect estimations of bedload transport in water courses. In April 2015, 30 impact sensors were installed in a new permanent measuring station to monitor continuously bedload transport in a mountain river with a large annual rate of sediment transport (around 90 000 m3 yr−1). Records of the first year of measurement showed that (i) the signal response in terms of geophone and accelerometer impulses is comparable for both types of sensors; (ii) there is a good correlation between discharge data and impulses recorded by both types of sensors; (iii) the critical discharge at the start of bedload transport is around 5 m3 s−1; (iv) a mean calibration factor for the geophone impulses can be estimated which is in a similar range as values determined from other sites with field calibration measurements.
Real-World Outcomes of Anti-VEGF Treatment for Retinal Vein Occlusion in Portugal
Authors: Vaz-Pereira Sara , Marques Inês P. , Matias João , Mira Filipe , Ribeiro Lígia , Flores Rita 
Published: March 2017

Purpose Retinal vein occlusion (RVO) is an important cause of visual disability in the modern world. We aim to evaluate the real-world outcomes of patients with RVO treated with anti-vascular endothelial growth factor (VEGF) in Portugal. Methods We performed a retrospective, observational, multicenter study including 8 centers across Portugal and 200 patients treated with either ranibizumab or bevacizumab. Data were collected at 3 time points: time of diagnosis (0 time point) and 6 and 12 months after initiating treatment. Demographic and clinical data were collected. Results Median visual acuity (VA) and central macular thickness (CMT) improved in the branch RVO (BRVO), central RVO (CRVO), bevacizumab, and ranibizumab groups at 6 and 12 months compared to baseline, with CMT improving further only in the CRVO and ranibizumab groups between 6 and 12 months (p = 0.002 and p = 0.001, respectively). The CMT was lower in the ranibizumab group compared to the bevacizumab group both at 6 and 12 months (p<0.02). Median CMT improved in both the good and poor baseline VA groups at 6 and 12 months compared to baseline (p<0.001). Median VA only improved for the group with poor baseline VA at 6 and 12 months of follow-up (p<0.001). Regression analysis identified several baseline variables as predictors of visual outcomes at 6 and 12 months, with different results depending on the analyzed group. Conclusions Both treatments were effective, although less effective than results reported in clinical trials. The morphologic response was better with ranibizumab compared to bevacizumab, although functionally there were no differences.
Clinical Relevance of Antimicrobial Testing Results for Dental Restorative Materials
Authors: Farrugia Cher , Haider Julie , Camilleri Liberato , Camilleri Josette 
Published: March 2017

Background The antimicrobial activity of restorative materials is clinically relevant because all dental materials are subject to an environment containing bacteria. This study aimed to investigate the use of 2 methodologies referred to in the literature to assess antimicrobial properties of restorative materials and investigate whether material properties alter results of these traditional methodologies. Methods A number of dental restorative materials – namely, Chemfil Superior®, Spectrum®, Heliobond®, Ionoseal®, Dyract Extra®, Smart Dentin Replacement (SDR®) and Biodentine® – were characterized by scanning electron microscopy (SEM), energy-dispersive spectroscopy (EDS), X-ray diffraction (XRD) analysis, Fourier transform infrared (FT-IR) spectroscopy and pH analysis. Antimicrobial activity was assessed using agar diffusion and biofilm accumulation tests. Key factors affecting results were assessed using analysis of covariance. Results Biodentine after immediate mixing and Ionoseal aged for 6 weeks resulted in an inhibition zone, while significantly higher McFarland readings were observed in the presence of barium when using materials Ionoseal, Dyract and SDR at 24-hour aging. Through analysis of covariance it was shown that material properties affected methodology results. Conclusions Properties of materials affect results of antimicrobial testing, but this may not directly reflect the antimicrobial potential of the material in question. Careful choice of methodology and interpretation of results is important.