bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gloggnitz contract after completion of the intermediate access at Göstritz
Authors: Haas Dieter , Schachinger Tobias , Lechner Gerhild , Knopf Rudolf 
Published: December 2017

AbstractThe intermediate construction access at Göstritz was planned based on the results of a comprehensive geological investigation programme. The intermediate access minimises the risk of the excavation of the Semmering Base Tunnel through the Grassberg‐Schlagl fault system, which is located in the Otterstock area in Lower Austria. The site consists of an approx. 1000 m long access tunnel, a complex system of shaft head caverns, two shafts with a depth of about 250 m down to the level of the tunnel as well as a system of shaft bottom caverns for the four tunnel drives in the directions of Gloggnitz and Mürzzuschlag. During the construction of the access tunnel, a new shaft head layout was proposed by the contractor in form of value engineering to optimize further construction operation, and the optimized layout was adopted to the contract. At the end of the access tunnel, it turned out that the shaft head cavern system could neither be constructed in the original layout as tendered nor in the newly revised layout due to a geological fault zone, which had not been predicted despite extensive geological investigation in advance. Consequently, ÖBB, designer and contractor worked intensively to find a new feasible design to enable further construction of the cavern system, avoid a standstill of tunnelling works and comply with all approvals.
A review of the Early Mesozoic granitoids in the Qinling Orogen: Implication for gold metallogeny
Authors: Yang Gaoxue , Li Yongjun , Tong Lili , Duan Fenghao , Wang Zuopeng , Wu Le , Ning Wentao 
Published: December 2017

The Qinling Orogen is located between the North China and South China blocks, and considered to form by the multiple accretionary processes, being also characterized by development of voluminous magmatic intrusions as well as abundant mineral resources. Here we compile the geological, geochemical and geochronological data of the Early Mesozoic granitoids from the Qingling Orogen and attempt to constrain the Early Mesozoic tectonic evolution and mechanism of gold mineralization in this region. The Early Mesozoic granitoids are most widespread in the Qinling Orogen, especially in western part, and can be classified into S‐, I‐, I‐A‐types, with the I‐type constituting the major variety. The isotopic ages of the three types granitoids are 200–222 Ma, 185–248 Ma, 210–227 Ma, respectively, indicating overlapping ages with a wide span of I‐type granitoids. The S‐, I‐, I‐A‐type granitoids show obvious zonation characteristics, that is the S‐type granitoids only occurred in southern South Qinling Belt, the I‐type granitoids are most widespread in the western Qinling Orogen, and the I‐A‐type granitoids are mainly exposed in the North Qinling Belt. The S‐type granitoids crystallized at relatively low temperature (800–850 °C) and deep‐crustal level (ca. 8 kb) and derived mainly from partial melting of a clay‐poor psammitic source. The I‐type granitoids formed at high temperature (>925 °C) and pressures above the garnet‐in phase boundary (>1.2 GPa) and derived from greywackes and partially igneous source. Moreover, the I‐A‐type granitoids probably derived from distinct sources with sufficient interaction, or common origin but underwent different degrees of crustal contamination, and generated at high temperatures (ca. 950 °C) and low pressures (1.0–0.2 GPa) conditions. These features indicate the Qinling Orogen experienced subduction, syn‐collisional, and post‐collisional during the Early Mesozoic, and also suggest the S‐, I‐, I‐A‐types granitoids underwent an episodic growth documenting the tectonic regime switchover at this stage. The gold deposits in the western Qinling Orogen can be classified as orogenic, Carlin‐type, and Carlin‐like gold deposits with the formation age of Late Triassic. The orogenic and Carlin‐type gold deposits have no genetic relation to granitic magmatism, but the Carlin‐like gold deposits is related to the synchronous magmatism. Combined with regional geology and metallogenic systems, we suggest that the multi‐stage Qinling Orogenesis resulted in the formation of the Early Mesozoic S‐, I‐, I‐A‐type granitoids and different types of gold deposits with some characteristic differences.
Geochemical characteristics and tectonic setting of the bimodal volcanic rocks in Sepikou region of eastern Tianshan
Authors: Gao Jinggang , Wang Xiaohu , Gao Yunxia , Zhou Yi , Fan Tingbin , Zhang Ning 
Published: December 2017

The Sepikou region is located in the eastern Bogda Mountains of the east Tianshan. The Bogda belt is mainly composed of Carboniferous strata, including the Lower Carboniferous Qijiaojing Formation (C1q), Upper Carboniferous Liushugou Formation (C2l), and Qijiagou Formation (C2qj). Here, we report the petrology, geochemistry, and geochronology of bimodal volcanic rocks from the Upper Carboniferous Liushugou Formation, which is widely distributed in the Sepikou region. The basalts, basaltic andesite, and keratophyre have similar petrochemical characteristics and exhibit the high‐Na, low‐K characteristics belonging to calc‐alkalic rocks. These are characterized by the high abundance of K, Rb, Th, Ba, the depletion of HFSE (Nb, Ta, Zr, and Hf), and the slight depletion of Ti. Chondrite‐normalized rare‐earth elements (REE) patterns for basalts‐keratophyre show right‐leaning parallel curve clusters, together with a slight enrichment in light rare‐earth elements (LREE) contents and low heavy rare‐earth elements (HREE)/LREE ratios. The keratophyre exhibits slightly negative Eu anomalies. Compared with the basalts, the rhyolites have high alkali contents, slightly high ∑REE contents, low heavy rare‐earth elements/LREE ratios, negative εSr(t) (−9.1 to −12.0), low 87Sr/86Sr initial ratio, highly positive εNd (t) (+5.3 to +6.4), and low Pb isotope ratios. The fractionated REE patterns with prominent negative Eu anomalies suggest they were chiefly derived from the mantle magma underplated basaltic body remelting from the depleted mantle source. The LA‐ICP‐MS analysis on zircons from quartz keratophyre and rhyolite yield similar ages of 314.9 ± 1.2 and 314.0 ± 1.1 Ma, respectively, suggest that the major bimodal volcanism took place in the Late Carboniferous epoch. The quartz keratophyre zircons, with the 176Hf/177Hf ratios of 0.282897–0.283097, have highly positive εHf (10.99–19.97) and depleted mantle model ages between 180 and 628 Ma. The mafic rocks were chiefly derived from the depleted mantle with the partial incorporation of crustal components. The bimodal volcanic rocks were formed under a continental rift setting. The rift experienced extension in the early period of the Early Carboniferous and its final closure arose after a late period of the Late Carboniferous.
Global bioethics
Authors: Neuhaus Carolyn P. 
Published: December 2017

AbstractThis August, I participated in the conference “Genome Editing: Biomedical and Ethical Perspectives,” hosted by the Center for the Study of Bioethics at the University of Belgrade and cosponsored by the Division of Medical Ethics of NYU Langone Health and The Hastings Center. The prime minister of Serbia, Ana Brnabić, spoke of the significance of bringing together an international community of bioethicists, acknowledging that ethical, social, and legal issues surrounding gene editing technologies transcend national boundaries. Europe's Oviedo Convention prohibits human germline gene editing, and UNESCO's Universal Declaration on the Human Genome and Human Rights says that germline editing “could be contrary to human dignity,” an assault on humanity itself. Whether one agrees or not, engaging with the idea forces us to think about what it means to be part of the global human community and about the moral significance of the human genome to creating that community. The conference highlighted for me how challenging having international, much less global, conversations about bioethics can be.
Public Health Autonomy: A Critical Reappraisal
Authors: Zimmerman Frederick J. 
Published: December 2017

AbstractThe ethical principle of autonomy is among the most fundamental in ethics, and it is particularly salient for those in public health, who must constantly balance the desire to improve health outcomes by changing behavior with respect for individual freedom. Although there are some areas in which there is a genuine tension between public health and autonomy—childhood vaccine mandates, for example—there are many more areas where not only is there no tension, but public health and autonomy come down to the same thing. These areas of overlap are often rendered invisible by a thin understanding of autonomy. Better integrating newer theoretical insights about autonomy into applied ethics can make discussions of public health ethics more rigorous, incisive, and effective. Even more importantly, bringing modern concepts of autonomy into public health ethics can showcase the many areas in which public health and autonomy have the same goals, face the same threats, and can be mutually advanced by the same kinds of solutions.This article provides a schema for relational autonomy in a public health context and gives concrete examples of how autonomy can be served through public‐health interventions. It marshals insights from sociology, psychology, and philosophy to advance a theory of autonomy and coercion that recognizes three potential threats to autonomy: threats to choice sets, threats to knowledge, and threats to preferences.
Being Better Bodies
Authors: Reynolds Joel Michael 
Published: December 2017

AbstractBioethics has an uneasy relationship with embodiment. Only with vigilance does knowledge of the body as it is lived counterbalance the momentous inertia of knowledge of the body as an object brought about by modern medical sciences. As a field tethered to detached, technical ways of knowing the world, bioethics must toil to treat the body as more than mere material and machine. To be more is, among other things, to be social—to live in the thickets of interdependence and the institutions and practices we build, hone, and defend to facilitate it. I take this tension to define the ultimate stakes of Melinda Hall's The Bioethics of Enhancement: Transhumanism, Disability, and Biopolitics. Hall homes in on transhumanism, the idea that we should embrace technology to vault beyond current human limitations. Yet the work serves as a reminder for all bioethicists and philosophers of how easily one can be led astray by otherwise irreproachable values when they are disconnected from the conditions and realities of human life, including being irremediably interdependent embodied beings. Put more acerbically, the book is a reminder of how thinking goes wrong when divorced from the principal sources out of which human appraisals emerge: our fleshy, messy, social bodies.
Reproductive Rights without Resources or Recourse
Authors: Mutcherson Kimberly 
Published: December 2017

AbstractThe U.S. Supreme Court declared procreation to be a fundamental right in the early twentieth century in a case involving Oklahoma's Habitual Criminal Sterilization Act, an act that permitted unconsented sterilization of individuals convicted of certain crimes. The right that the Court articulated in that case is a negative right: it requires that the government not place unjustified roadblocks in the way of people seeking to procreate, but it does not require the government to take positive steps to help people procreate if they wish to. I argue that a positive legal right is morally necessary in the United States, given the profound significance of procreation, the current barriers to access to care, and the related issues of individual and societal justice. I assume at the outset that the right to procreate should be expansive enough to include a right to noncoital reproduction. The absence of a positive right to procreate reflects not just constitutional tradition but also a governmental and societal commitment to a longstanding set of reproductive hierarchies by which those who fall outside of the traditional framing of family too frequently find their procreative dreams hindered. Reconceiving procreative rights to include a positive right would create greater opportunities to argue and lobby for increased access to technologies that are out of reach for many.
How the Criminalization of Pregnancy Robs Women of Reproductive Autonomy
Authors: Goodwin Michele 
Published: December 2017

AbstractIn 2003, the South Carolina Supreme Court upheld the conviction of Regina McKnight, an African American woman who was convicted at the age of twenty‐two for committing “homicide by child abuse.” She became the first woman in the United States to be arrested, prosecuted, and convicted for experiencing a stillbirth. Rather than an outlier case in the annals of American jurisprudence that stretched law beyond reason while restraining compassion and justice, McKnight's conviction inspired similar prosecutions of other poor black women and then of other women. More than one‐third of states consider pregnant women's illicit drug use a form of child abuse, resulting in unprecedented forms of criminal and civil punishment. Laws previously understood to protect pregnant women from domestic violence during pregnancy, such as fetal protection laws, now serve as the vehicles for prosecuting pregnant women. What these prosecutions and laws expose are the multitudinous ways in which the criminalization of poor pregnant women—and normalization of that criminalization, such that even doctors and nurses are expected to participate in it—serve to humiliate women, interfere with their reproductive health, and ultimately rob women of reproductive autonomy.
The Shifting Landscape of Prenatal Testing: Between Reproductive Autonomy and Public Health
Authors: Ravitsky Vardit 
Published: December 2017

AbstractSince the 1970s, prenatal testing has been integrated into many health care systems on the basis of two competing and largely irreconcilable rationales. The reproductive autonomy rationale focuses on nondirective counseling and consent as ways to ensure that women's decisions about testing and subsequent care are informed and free of undue pressures. It also represents an easily understandable and ethically convincing basis for widespread access to prenatal testing, since the value of autonomy is well established in Western bioethics and widely recognized by funders of health care. In contrast, the public health rationale approaches prenatal testing as designed to reduce the incidence of certain conditions in the population to reduce the burden of disease. This rationale emphasizes the societal consequences of reproduction and the aggregate impact of women's individual reproductive decisions on the overall health of future populations. In this essay, I argue that, despite what could be seen as a persistent failure to meet the ideals of reproductive autonomy, resisting the public health rationale as a basis for prenatal screening is ethically and pragmatically crucial. I recommend policy mechanisms that can enhance reproductive autonomy at a societal level to support choice at the individual level.
Should Clinicians Set Limits on Reproductive Autonomy?
Authors: King Louise P. 
Published: December 2017

AbstractAs a gynecologic surgeon with a focus on infertility, I frequently hold complex discussions with patients, exploring with them the risks and benefits of surgical options. In the past, we physicians may have expected our patients to simply defer to our expertise and choose from the options we presented. In our contemporary era, however, patients frequently request options not favored by their physicians and even some they've found themselves online. In reproductive endocrinology and infertility, the range of options that may be offered or that patients may themselves seek out is continuously widening. Physicians certainly seek to find the option that will result in the best outcome for their patients, but the information to guide us in achieving the best outcome can be vague or conflicting. Add to this the financial and emotional pressures bearing on patients seeking assisted reproduction. In this essay, I explore the extent to which clinicians in reproductive medicine should follow patient requests with which they disagree or instead try to persuade the patient to do something else or simply refuse outright to meet the request. And if persuasion is to be used, what would be legitimate methods? Clearly, coercion is unacceptable, but the line between persuasion and coercion can be elusive. At what point can or should clinicians resist such requests—and to what degree?
Reproductive Autonomy and Regulation—Coexistence in Action
Authors: Deech Ruth 
Published: December 2017

AbstractOn occasion, British in vitro fertilization practitioners look over the ocean to the practice of IVF and embryo research in the United States, wonder why these areas are subject to less regulation than in the United Kingdom, and ask how much less risky and more progressive IVF and embryo research might be if subject to additional federal, or at least state, regulation. To an American audience, imbued with the centuries‐old spirit of independence, regulation and autonomy can seem in tension. From a British perspective, there is no necessary conflict. There is no dissent in the United Kingdom from the proposition that individual activities, services, and industries can be regulated and, at the same time, retain and exercise such autonomy as is their right within a safe sphere. From 1994 to 2002, I was the chair of the United Kingdom's Human Fertilisation and Embryology Authority, which regulates the practice of IVF and embryo research. The existence of the HFEA assures patients that safety and aspects of the practice of assisted reproduction are monitored, leaving them free to choose without worrying about danger, in the same way that the public may take only those drugs that have passed health and safety tests. I would propose that anxious and vulnerable patients do not have more autonomy in a less regulated, market‐driven field.
Multimodal sensor medical image fusion based on mutual‐structure for joint filtering using sparse representation
Authors: Li Weisheng , Xu Xiaofan , Du Jiao 
Published: December 2017

AbstractMultimodal sensor medical image fusion has been widely reported in recent years, but the fused image by the existing methods introduces low contrast information and little detail information. To overcome this problem, the new image fusion method is proposed based on mutual‐structure for joint filtering and sparse representation in this article. First, the source image is decomposed into a series of detail images and coarse images by mutual‐structure for joint filtering. Second, sparse representation is adopted to fuse coarse images and then local contrast is applied for fusing detail images. Finally, the fused image is reconstructed by the addition of the fused coarse images and the fused detail images. By experimental results, the proposed method shows the best performance on preserving detail information and contrast information in the views of subjective and objective evaluations.
Strike kinematics and performance in juvenile ball pythons (Python regius)
Authors: Ryerson William G , Tan Weimin 
Published: December 2017

AbstractThe rapid strike of snakes has interested researchers for decades. Although most work has focused on the strike performance of vipers, recent work has shown that other snakes outside of the Viperidae can strike with the same velocities and accelerations. However, to date all of these examples focus on performance in adult snakes. Here, we use high‐speed video to measure the strike kinematics and performance of 10 juvenile (<6 months of age) ball pythons,Python regius. We find that juvenileP. regiusstrike at levels comparable to larger snakes, but with shorter durations and over shorter distances. We conclude that the juvenileP. regiusmaintain performance likely through manipulation of the axial musculature and accompanying elastic tissues, and that this is a first step to understanding ontogenetic changes in behavior and a potential avenue for understanding how captivity may also impact behavior.
HIV viral load monitoring among key populations in low‐ and middle‐income countries: challenges and opportunities
Authors: Schwartz Sheree R , Kavanagh Matthew M , Sugarman Jeremy , Solomon Sunil S , Njindam Illiassou M , Rebe Kevin , Quinn Thomas C , Toure‐Kane Coumba , Beyrer Chris , Baral Stefan 
Published: December 2017

AbstractIntroductionKey populations bear a disproportionate HIV burden and have substantial unmet treatment needs. Routine viral load monitoring represents the gold standard for assessing treatment response at the individual and programme levels; at the population‐level, community viral load is a metric of HIV programme effectiveness and can identify “hotspots” of HIV transmission. Nevertheless, there are specific implementation and ethical challenges to effectively operationalize and meaningfully interpret viral load data at the community level among these often marginalized populations.DiscussionViral load monitoring enhances HIV treatment, and programme evaluation, and offers a better understanding of HIV surveillance and epidemic trends. Programmatically, viral load monitoring can provide data related to HIV service delivery coverage and quality, as well as inequities in treatment access and uptake. From a population perspective, community viral load data provides information on HIV transmission risk. Furthermore, viral load data can be used as an advocacy tool to demonstrate differences in service delivery and to promote allocation of resources to disproportionately affected key populations and communities with suboptimal health outcomes. However, in order to perform viral load monitoring for individual and programme benefit, health surveillance and advocacy purposes, careful consideration must be given to how such key population programmes are designed and implemented. For example, HIV risk factors, such as particular sex practices, sex work and drug use, are stigmatized or even criminalized in many contexts. Consequently, efforts must be taken so that routine viral load monitoring among marginalized populations does not cause inadvertent harm. Furthermore, given the challenges of reaching representative samples of key populations, significant attention to meaningful recruitment, decentralization of care and interpretation of results is needed. Finally, improving the interoperability of health systems through judicious use of biometrics or identifiers when confidentiality can be maintained is important to generate more valuable data to inform monitoring programmes.ConclusionsOpportunities for expanded viral load monitoring could and should benefit all those affected by HIV, including key populations. The promise of the increasing routinization of viral load monitoring as a tool to advance HIV treatment equity is great and should be prioritized and appropriately implemented within key population programmatic and research agendas.