bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENURUNAN CONTAINER INDEX (CI) MELALUI PENERAPAN OVITRAP DI SEKOLAH DASAR KOTA SEMARANG
Authors: Cahyati Widya Hary , Sukendra Dyah Mahendrasari , PS Yunita Dyah 
Published: September 2017

Abstrak
Penggunaan ovitrap terbuat dari botol plastik bekas dan diisi atraktan merupakan salah satu upaya sederhana serta mampu menurunkan populasi nyamuk. Angka Bebas Jentik (ABJ) merupakan salah satu indikator untuk mengetahui tingginya atau rendahnya populasi nyamuk pada suatu lingkungan. ABJ Kota Semarang tahun 2015 yaitu 59%, masih di bawah target (<95%). Tujuan penelitian yaitu untuk mengetahui kemampuan penerapan ovitrap berbasis sekolah dalam menurunkan container index (CI). Jenis penelitian yaitu eksperimen semu, dengan populasi seluruh sekolah dasar di Kota Semarang dan sampelnya yaitu 4 sekolah dasar : SDN Sekaran 01, SDN Pedurungan Tengah 02, SDN Petompon 01, dan SD Tugurejo. Hasil penelitian menunjukkan bahwa penerapan ovitrap mampu menurunkan CI. CI sebelum dan setelah penerapan ovitrap di sekolah menunjukkan penurunan sebesar 40% untuk SDN Sekaran 01, 43% untuk SD Pedurungan Tengah, 57% untuk SDN Petompon 01, dan 25% untuk SDN Tugurejo. Simpulan dalam penelitian ini penerapan ovitrap berbasis sekolah mampu menurunkan CI.

Abstract
Aplication of ovitrap made from plastic bottle and filled attractan is one of the ways to reduce mosquitoes population. LFI Semarang in 2015 is 59 %, still under the target (<95%). The purpose of research to determine the effectiveness of implementation of school-based ovitrap to reduce the population of Aedes. Design research was a quasi experiment, and the population are elementary schools in Semarang City also the sample are SDN Sekaran 01, SDN Pedurungan Tengah 02, SDN Petompon 01, and SDN Tugurejo. The results showed that the application of ovitrap effective to reduce the container index (CI). Before and after the application of ovitrap in schools, the CI showed a decrease : 40% in SDN Sekaran 01, 43% in SD Central Pedurungan, 57% in SDN Petompon 01, and 25% in SDN Tugurejo. The conclusion in this study is ovitrap school-based application is capable to reduce the CI.
Manajemen Sumber Daya Terhadap Mutu Pelayanan Neonatus Di Puskesmas PONED Oesao Kupang
Authors: Fai Isterina Felandina , Pandie David B.W , Ludji Ina Debora Ratu 
Published: September 2017

Terdapat 9 kasus kematian neonatus di tahun 2015 di Puskesmas Oesao.Ditinjau dari aspek sumber daya manusia, aspek peralatan, aspek obataspek bangunan, aspek SOP belum memenuhi syarat. Penelitian ini bertujuan untuk menganalisis pengaruh manajemen sumber daya secara parsial dan simultan terhadap mutu pelayanan neonatus.Jenis penelitian yang digunakan dalam penelitian ini adalahObservasional Analitik desain cross sectional. Lokasi penelitian di Puskesmas Oesao Oesao Kabupaten Kupang. Populasi dalam penelitian ini adalah semua ibu yang memiliki neonatus di wilayah kerja Puskesmas Oesao dari bulan Januari sampai September 2015 sebanyak 396 orang ibu, teknik pengambilan sampel menggunakan teknik sampling acak sederhana dan sampel penelitian sebanyak 67 ibu yang memiliki neonatus. Hasil analisis univariat menunjukkan bahwa aspek SDM, spek peralatan, aspek obat, aspek bangunan, aspek SOP dan mutu pelayanan neonatus termasuk dalam kategori baik. Hasil Analisis bivariat menunjukkan bahwa secara parsial ada pengaruh antara aspek SDM (p value = 0,004), aspek obat(p value = 0,004) terhadap mutu pelayanan neonatus. Hasil analisis multivariat menunjukkan bahwa secara simultan ada pengaruh antara Aspek SDM (p value = 0,004) dan aspek obat (p value = 0,004) terhadap mutu pelayanan neonatus.
Public Health Center Oesao was considered under perform in term of aspect of human resources, aspects of equipment, aspects of medicine, aspects of the building, and on procedural aspects. At same time, there were 9 cases of neonatal deaths in 2015. This study aimed to analyze the influence of resource management partially and simultaneously on the quality of neonatal care. This type of research used in this study was observational analytical cross-sectional design. The population in this study are all mothers who had newborns in PHC Oesao from January to September 2015 as many as 396 people a mother, a technique of sampling using simple random sampling and samples are 67 mothers with newborns. Results of univariate analysis showed that the human resources aspect, spec equipment, medicine aspects, aspects of the building, the quality aspects of the draft SOP neonatal care included in both categories. The results of the bivariate analysis showed that partial no influence between aspects of HR (p=0.004), Aspects of Medicines (p=0.004) on the quality of Neonatal Care. Multivariate analysis showed that simultaneously there is influence between the human resources aspect (p=0.004) and Aspects of Medicine (p=0.004) on the Quality Neonatal Services. It was recommendet to further enhance regular supervision to improve the quality, quantity, resource management and quality neonatal care.
KOMUNIKASI ORANGTUA-REMAJA DAN PENDIDIKAN ORANGTUA DENGAN PERILAKU SEKSUAL BERISIKO PADA REMAJA
Authors: Gustina Erni 
Published: September 2017

Pacaran dan perilaku seksual berkaitan erat satu sama lain. Pacaran akan menghadapkan remaja pada kondisi yang meningkatkan pengalaman seksual. Dilaporkan bahwa perilaku berciuman (48% remaja laki-laki, 30% remaja perempuan), petting (30% remaja laki-laki, 6% remaja perempuan). Tujuan penelitian untuk mengetahui hubungan komunikasi orangtua-remaja, pendidikan orangtua dengan perilaku seksual berisiko pada remaja Tahun 2015. Penelitian ini adalah observasional analitik dengan rancangan cross sectional. Besar sampel adalah 88 orang. Teknik sampling adalah total sampling. Analisa data menggunakan chi square dan regresi logistik. Hasil penelitian didapatkan perilaku seksual remaja risiko rendah (91,2%), komunikasi orangtua-remaja baik (57,2%). Ada hubungan komunikasi orangtua-remaja dengan perilaku seksual berisiko (p=0,03), ada hubungan pendidikan orangtua dengan perilaku seksual berisiko (p=0,04). Simpulan penelitian ada hubungan komunikasi orangtua-remaja, pendidikan orangtua dengan perilaku seksual berisiko dan komunikasi orangtua-remaja merupakan variabel dominan berhubungan dengan perilaku seksual berisiko pada remaja.

Dating and sexual behaviors are closely related to one another. Dating will confront adolescents in conditions that increased the sexual experience. Reported that the behavior of kissing (48% boys, 30% girls), petting (30% boys, 6% girl). The aimed of research to determine the relationship parent-adolescent communication, education of parents with risky sexual behavior in adolescents Year 2015. This study was observational analytic with cross sectional design. The sample size are 88 people. Sampling technique was total sampling. Data were analyzed using chi square and logistic regression. The result showed a low risk of adolescent sexual behavior (91.2%), parent-adolescent communication is good (57.2%). There was a relathionship parent-adolescent communication with risky sexual behavior (p=0.03), there was relationship with the parent education risky sexual behavior (p=0.04). The conclusions of research there was a relationship parent-adolescent communication, education of parents with risky sexual behavior and parent-teenager communication is the dominant variable associated with risky sexual behavior in adolescents.
PERILAKU KONSUMSI MINUMAN RINGAN (SOFTDRINK) DAN PH SALIVA DENGAN KEJADIAN KARIES GIGI
Authors: Fitriati Nur , Hernawan Andri Dwi , Trisnawati Elly 
Published: September 2017

Abstrak
Karies gigi adalah penyakit dengan sejumlah faktor risiko yang ditandai dengan demineralisasi pada gigi. Minuman ringan merupakan faktor ekstrinsik kejadian karies gigi. Data Riskesdas (2013) menunjukkan prevalensi penduduk Indonesia yang bermasalah dengan penyakit gigi dan mulut sebanyak 25,9% dan prevalensi provinsi Kalimantan Barat adalah 20,6%. Prevalensi karies gigi umur 10-14 tahun menurut Profil Kesehatan Kota Pontianak meningkat dari 26,9% (2014) menjadi 30,1% (2015). Tujuan penelitian ini untuk mengetahui hubungan antara konsumsi minuman ringan dengan pH saliva dan kejadian karies gigi pada siswa kelas V SD Binaan UPTD Kecamatan Pontianak Timur Tahun 2016.
Penelitian ini menggunakan desain cross sectionaldengan jumlah sampel 159 orang. Hasil penelitian menunjukkan terdapat hubungan yang bermakna pada variabel frekuensi konsumsi (p value=0,001), waktukonsumsi (p value=0,008), cara konsumsi (p value=0,000), perilaku setelah konsumsi (p value=0,000) dengan pH saliva dan adanya hubungan bermakna antara pH saliva (p value=0,000), angka OHIS (p value=0,022) dengan kejadian karies gigi.
Abstract
Dental caries is disease with a number of risk factors characterized by deminineralization of the tooth. Softdrinks are extrinsic factors on the incidence of dental caries. Riskesdas (2013) indicating that prevalence of West Kalimantan province was 20,6%. The prevalence of dental caries in the 10-14 years age according to Pontianak City Health Profile increased from 26,9% (2014) to 30,1% (2015). The objective of the research is to determine the the relationship between the consumption of softdrinks with pH saliva and the incidence of dental caries in primary school students of class V Patronage UPTD Eastern District of Pontianak 2016.
The research is using cross sectional design with a sample of 159 people. The results is obtained a significant relationship to the variable frequency of consumption (p value = 0,001), time consumption (p value = 0,008), how consumption (p value = 0,000), behavior after consumption (p value = 0,000) with pH saliva and the relationship between pH saliva (p value = 0,000), number OHIS (p value = 0,022) with the incidence of dental caries.
PERAN PETUGAS GIZI DALAM MEMBERIKAN PELAYANAN ASUHAN GIZI PADA PASIEN RAWAT INAP
Authors: Sulistiyanto Anggara Dwi , Handayani Oktia Woro Kasmini , Rustiana Eunike R 
Published: September 2017

Abstrak

Pelayanan gizi rumah sakit merupakan bagian yang sangat vital dari sistem pelayanan paripurna terhadap pasien di rumah sakit.Pelayanan gizi diberikan agar pasien mencapai kondisi yang optimal dalam memenuhi kebutuhan giziataupun mengoreksi kelainan metabolisme. Penelitian ini mengenai bagaimana peran petugas gizi dalam memberikan pelayanan asuhan gizi kepada pasien rawat inap di RSUD dr. R. Soetrasno Kabupaten Rembang. Jenis penelitian adalah penelitian observasional dengan pendekatan kualitatif yang mendekripsikan objek dengan mengamati, melakukan wawancara serta mencatat bagaimana petugas gizi memberikan pelayanan asuhan gizi. Data sampel diambil secara purposive sampling dengan jumlah responden 7 orang. Petugas gizi sudah melaksanakan dengan baik sesuai dengan perannya yaitu melakukan monitoring dan evaluasi pasien terhadap dampak asuhan giziserta melaporkan hasil asuhan gizi kepada dokter atau tenaga kesehatan lain. Perlu pembentukan tim terapi gizi tersandart dengan melibatkan tenaga kesehatan lain agar pelayanan gizi rumah sakit lebih optimal.

Abstract
The hospital nutrition care service is a vital part of the plenary service system to the patients in the hospital. Nutrition care services given to patients in order to achieve optimal conditions in fulfillment of nutritional needs or correcting metabolic abnormalities.This study was conducted to answer whether the role of nutritionists in providing nutrition care services to inpatients in dr. R. Soetrasno hospital, is in accordance with hospital nutrition care service or not.This study was an observational study using qualitative approach, that described object by observing, interviewing and making notes about how is the role of nutritionists. Data was taken using purposive sampling with 7 respondances.Nutritionists already performed their duties properly by doing evaluation to the inpatients and report the results of nutrition care services to the doctor or other health professionals. Hospitals need to create a qualified nutritional therapy team, involving other health professionals.
FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN PRAKTIK PENEMUAN PNEUMONIA BALITA OLEH BIDAN
Authors: Prabawa Hendra Eka , Azinar Muhammad 
Published: September 2017

ABSTRAK

Pneumonia merupakan pembunuh utama balita di dunia yang kurang mendapat perhatian bahkan terlupakan (“the forgotten killer”). Cakupan angka penemuan pneumonia balita di Indonesia tahun 2014 masih belum mencapai target yaitu 29,74% (target 80%). Rendahnya cakupan penemuan pneumonia balita disebabkan antara lain karena deteksi kasus oleh bidan sebagai pemberi pelayanan balita sakit di puskesmas masih rendah. Penelitian ini bertujuan untuk mengetahui faktor – faktor yang berhubungan dengan praktik penemuan pneumonia balita oleh bidan di puskesmas wilayah Kabupaten Pemalang. Metode penelitian ini berjenis explanatory research, menggunakan pendekatan cross sectional, dengan populasi penelitian adalah bidan yang bertugas di ruang rawat jalan KIA puskesmas di Kabupaten Pemalang berjumlah 242 orang. Teknik sampling secara purposive didapat 44 responden. Analisis data secara univariat dan bivariat dengan uji chi square. Hasil penelitian didapatkan faktor yang berhubungan dengan praktik penemuan pneumonia oleh bidan adalah pengetahuan (p=0,000), tugas rangkap (p=0,019), lama memegang program (p=0,007) dan dukungan kepala puskemas (p=0,000). Faktor yang tidak berhubungan adalah umur (p=1,000), sikap (p=0,773), ketersediaan fasilitas (p=0,117) dan dukungan mitra kerja (p=1,000).

ABSTRACT

Pneumonia is the main killer of children under five in the world who received less attention even forgotten ("the forgotten killer"). Coverage under five pneumonia detection rate in Indonesia in 2014 has yet to reach the target of 29.74% (target 80%). The low coverage of infant pneumonia is caused partly because the detection of cases by midwives as the service provider sick children in health centers is still low. This study aimed to identify factors related to the practice of the invention toddler pneumonia by midwives in health centers Pemalang district. This research method was explanatory research using cross sectional approach, the study population are midwife who served in the room KIA clinics in Pemalang amounted to 242 people. Purposive sampling technique obtained 44 respondents. Data analysis of univariate and bivariate with chi square test. The result showed that factors associated with the practice of the invention of pneumonia by midwives are knowledge (p = 0.000), double duty (p = 0.019), long held the program (p = 0.007) and the head support health centers (p = 0.000). Factors unrelated are age (p = 1.000), attitude (p = 0.773), the availability of facilities (p = 0.117) and the support of partners (p = 1.000).
PENGARUH PEMBERIAN BEDONG TERHADAP PERKEMBANGAN MOTORIK BAYI USIA 3 BULAN
Authors: Solikah Siti Nur , Suminar Saka 
Published: September 2017

Pemberian bedong sampai saat ini sudah menjadi tradisi pada masyarakat Indonesia khususnya di Jawa tengah. Sampai saat ini belum diketahui manfaat pentingnya pemberian bedong secara ilmiah tapi justru dapat menghambat perkembangan motorik karena sejak bayi lahir hingga usia tertentubayi tidak mendapatkan kesempatan bergerak bebas dan tidak mendapat stimulasi gerak dari lingkungan.Penelitian ini bertujuan untuk mengetahui pengaruhpemberian bedong terhadap perkembangan motorik pada bayi usia 3 bulan di Desa Cemani Kecamatan Grogol Kabupaten Sukoharjo.Jenis penelitian deskriptif komparatif dengan rancangan penelitian cross sectional. Populasi penelitian ini adalah bayi usia3 bulan di Desa Cemani sebanyak 28. Pengambilan sampel dilakukan dengan tehnik total sampling, jadi semua populasi diambil sebagai sampel penelitian. Instrumen penelitian menggunakan wawancara dan alat DDST. Uji hipotesis yang digunakan adalah uji t test independent.Analisis uji t test independent menunjukkan hasil signifikansi 0,000 (p < 0,05), maka Ho ditolak sehingga terdapat pengaruhpemberian bedong terhadap perkembangan motorik pada bayi usia 3 bulan di Desa Cemani Kecamatan Grogol Kabupaten Sukoharjo. Semakin lama bayi dibedong maka perkembangan motoriknya semakin suspeck, hal ini ditunjukkan dari nilai t -6,232.

Kata kunci: bedong, perkembangan motorik, bayi.

Abstract

The growth and physical development of a baby is considered as a golden age, a precious stage that influence for his or her entire life. Assessment of growth and development needs to be done to find whether a child's growth in normal range or not. Physical growth and achievement of ability occur quickly during the first year, one of which is motoric development. Infant motor development is influenced by several factors, one of which is culture such as baby wrapping for the newborn.This study aims to determine the effect of bedong on motor development in infants aged 3 months in the Village Cemani Grogol District Sukoharjo District. Using comparative descriptive research with cross sectional study design to all the infant age 3 months in Cemani 28 villages. The research instrument used interviews and DDST (Denver Development Screening Test) tools. Hypothesis test used is independent t test. Conclusion: Independent test t test analysis showed the result of significance 0.000 (p <0,05), hence Ho was rejected so that there was influence of giving of bedong to motor development at baby age 3 month in Cemani Village Grogol District Sukoharjo Regency. The longer the baby wrapped then more suspect motor development delayed, this is shown from the value of t -6.232.

Key Words : wrapping, motoric development, newborn
ID:3006 RNA Therapeutics and Anabolic Gene Delivery for Tissue Regeneration
Authors: Hu Yu-Chen 
Published: September 2017

Regenerative medicine requires coordinated functions of cells, materials and appropriate signaling. Recent years have witnessed the marriage of regenerative medicine and gene delivery by which various genes encoding anabolic/catabolic proteins or RNA therapeutics are delivered into cells to potentiate the tissue regeneration. This presentation will focus on the use of viral vectors for genetic modification of mesenchymal stem cells derived from bone marrow or adipose tissue for tissue regeneration. In particular, emphasis is placed on the applications of baculovirus, an emerging nonpathogenic gene delivery vector, for the delivery of various anabolic genes and miRNA mimics/sponges to repair tissues
ID3010 Wnt antagonism in cancer stem cells- targeting stemness of cancers via the Wnt-BETA catenin pathway
Authors: Warrier Sudha 
Published: September 2017

Cancer stem cells (CSCs) are hypothesized to be the pathological counterpart of normal somatic tissue stem cells. The CSC model proposes that tumours are hierarchically organised with a subset of tumour cells at their apex, which possess self-renewal and multilineage differentiation potential. Cancer stem cells, unlike the bulk of the cells within the tumor, are elusive to drug treatment and are unaffected on chemo and radiotherapy. These self-renewing cells are responsible for the flare up of cancer and remission long after treatment. Cancer stem cells have a capacity for unlimited self-renewal, as well as the ability to initiate and drive tumor progression in an animal model.
Activated Wnt/β-Catenin signaling is a key feature of epithelial cancers and is critical for metastasis and epithelial-mesenchymal transition (EMT) , a signature trait of CSCs. We explored the effect of the Wnt antagonist, secreted frizzled related protein 4 (sFRP4) in CSCs in gliomas. We found that sFRP4 chemo-sensitizes GSC-enriched cells to commonly used drugs, by the reversal of EMT and by decreasing drug effluxers. sFRP4 acts at multiple levels of the Wnt- β-Catenin and the Wnt- calcium pathways in inhibiting CSCs. We also identified a novel mechanism of action of sFRP4. These findings could be exploited for designing better targeted strategies to improve chemo-response and eventually eliminate glioblastoma CSCs.
ID2010 Cytotoxicity of aqueous and ethanolic bark extracts of Pithecellobium dulce against human carcinoma cells
Authors: Jalique Shella Mae 
Published: September 2017

Cancer cases continue to increase and kill humans. In this paper, we report a study based on anticancer properties of the aqueous and ethanolic bark extracts of Pithecellobium dulce. Anticancer activities were assayed with standard MTT colorimetric procedure against three human cancer cell lines namely breast (MCF-7), colon (HCT-116), and hepatocellular (HepG2) in different concentrations. The aqueous extract of the plant revealed the highest toxicity on hepatocellular carcinoma (HepG2) cancer cell line with cell viability of 1.71 percent. On the other hand, its ethanol extracts has the highest toxicity on colon carcinoma (HCT-116) with a percent viability of 6.05 percent. Based on the results, the bark of the plant can be used to prepare anticancer drug with proper standardization methods
ID:2041 Animal Component Free Medium Retains the Stability of Hypervariable Region 1 (HV1) of Mitochondrial DNA of Human Full Term Amniotic Fluid Mesenchymal Stem Cells
Authors: Rawi Rohayu Izanwati Mohd 
Published: September 2017

Therapeutic potential of human amniotic fluid (hAF) cells in treating human disease is very promising. Furthermore it provides an alternative in isolating stem cells from an accessible source, where the fluid is merely discarded, thus circumventing the ethical concerns. Mesenchymal stem cell (MSC) is one of the heterogenous cell populations in the amniotic fluid (AF), however, its role and potential for stem cell therapy are yet to be discovered. One of the criteria in establishing the clinical grade of MSCs is the ability of the cells to retain their genomic stability in vitro prior to bedside applications. The microenviroment niche of the culture medium used is important to generate the safe MSCs. As mitochondria play the vital role in metabolic task such as apoptosis and cell proliferation, therefore investigating mitochondria DNA (mtDNA) is essential to mark the stability of stem cell. In this study, we aimed to detect variations of mtDNA across the passage number of cultured human amniotic fluid MSCs (hAFMSCs), cultured in animal component free (ACF) medium, specialised for human MSCs. Polymorphisms of hypervariable region 1 (HV1) in the D-loop of mtDNA were investigated in a series of cultured hAFMSCs (passage 1 and 3) from three different samples (three biological replicates) as well as in their respective fresh samples (control). Extracted DNA samples were subjected to PCR to detect the sequence variations of HV1 (nt16024-16365). The sequences were then analysed using SeqScape v2.5 by comparing the sequences with The Cambridge Reference Sequence (rCRS) for human mtDNA. The common C-to-T transition at position 16223 (C16223T) for all three samples was identified. Another common base transition was also identified for the other two samples at position 16311 (T16311C).
However, one of the samples showed more variants; a C-to-T transition at position 16290 (C16290T), an A-to-G at position 16317 (A16317G) and a G-to-A at position 16319 (G16319A). All variants were identified within the sequence of around 341bp nucleotides and their polymorphisms frequency was consistent for all three samples regardless of their passage numbers when compared to control. This pattern of polymorphisms demonstrates the HV1 mtDNA integrity of hAFMSCs cultured in ACF medium, hence highly suggesting the ability of ACF medium in retaining the stability of stem cells mtDNA in vitro. The ACF medium may serve as a good medium in culturing hAFMSCs that is safe and stable for basic research in stem cell and therapeutic applications.