bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interest of systematic tomosynthesis (3D mammography) with synthetic 2D mammography in breast cancer screening
Authors: Liberatore Mathieu , Cucchi Jean-Michel , Fighiera Martine , Binet Anne , Missana Marie Christine , Brunner Philippe , Mourou Michel Yves , Iannessi Antoine 
Published: December 2017

Abstract
Full field digital mammography (FFDM) is the current pillar of breast cancer screening program. However, the emerging technique digital breast tomosynthesis (DBT) has demonstrated a significant increase in the sensibility of cancer detection in several large cohort trials. DBT is particularly helpful for young patients, dense breasts and soft masses due to its ability to reduce overlapping of tissue. In such a population of women, radiologists are more confident and the recall rates are reduced together with a higher positive predictive value. To reduce the breast absorbed doses of screened women and facilitate the workflow, a synthetized two-dimensional (2D) digital mammography (sDM) is obtained from DBT to replace the FFDM. No significant differences regarding detection of anomalies have been reported with respect to FFDM. These results validate a modern strategy for breast cancer screening supported by two views of DBT with sDM. In terms of mean absorbed doses, this strategy is around 1.5 mGy/view and almost equivalent to FFDM. In Europe, major limitations to such evolution are public health policies especially agreements and reimbursement for the technique being used in organized screening.
Study on Mechanical Properties for Shearing Breakage of Oat Kernel
Authors: Zhao Nan , Fu Nan , Li Dong , Wang Li-jun , Chen Xiao Dong 
Published: December 2017

Abstract
Breaking force, deformation, breaking energy, strength, hardness and rigidity of oat kernel under different loading rates (0.02, 0.04, 0.06, 0.08 and 0.10 mm/s) and loading position (ventral and dorsal sides) were determined within a moisture content range of 15.7 %–27.5 % (w.b.) by using a texture analyzer (TA) to investigate mechanical properties for shearing breakage of oat kernel. Complete randomized design was experimented to construct the force–distance curve. In this study, these mechanical properties of oat kernel were expressed as a function of moisture content and loading rate respectively. The result showed that breaking force, energy, strength, hardness and rigidity decreased linearly with the increasing moisture content and increased firstly and decreased then with the increasing loading rate. Deformation had an increasing trend with the increase in moisture content and loading rate. The highest values of breaking force, breaking energy, strength, hardness and rigidity were obtained at 0.08 mm/s loading rate. Moreover the dorsal side of oat kernel had a better shearing capacity compared with ventral side, which reflected in that breaking force, strength and hardness were great significantly at 95 % confident level when dorsal side was loaded.
Lizenz- und Gestattungsproduktion westdeutscher Unternehmen in der ČSSR und der DDR
Authors: Szobi Pavel 
Published: December 2017

Abstract
The article deals with economic relations between the Federal Republic of Germany, German Democratic Republic and Czechoslovakia during the Cold War. Using the example of licensed production, its aim is to illustrate that in spite of ideological boundaries, business relations between West and East flourished in the period of the 1970s and 1980s. The author characterizes institutional conditions for this cooperation, names individual cooperation attempts, and uses the example of the well-known German brand Nivea as a symbol of the West and an example of a successful cooperation. The article reveals the intensive activities of West German companies and their investments in the GDR and Czechoslovakia long before 1989 and shows the potential of analyzing the German-German and the European transformation after 1989 more under the perspective of continuities and discontinuities.
An Efficient Technique for Three-Dimensional Image Visualization Through Two-Dimensional Images for Medical Data
Authors: Gunasekaran Ganesan , Venkatesan Meenakshisundaram 
Published: December 2017

Abstract
The main idea behind this work is to present three-dimensional (3D) image visualization through two-dimensional (2D) images that comprise various images. 3D image visualization is one of the essential methods for excerpting data from given pieces. The main goal of this work is to figure out the outlines of the given 3D geometric primitives in each part, and then integrate these outlines or frames to reconstruct 3D geometric primitives. The proposed technique is very useful and can be applied to many kinds of images. The experimental results showed a very good determination of the reconstructing process of 2D images.
Performance Evaluation of Wavelet-Based Optical Wireless System using On-Off Keying Modulation
Authors: Monga Himanshu , Rani Shilpa , Mehta Pooja 
Published: December 2017

Abstract
The paper investigates the performance of DWT (Discrete Wavelet Transform) and CWT (Continuous Wavelet Transform) techniques based on On – Off keying modulation (OOK) for reduced BER with increase in SNR in optical wireless system. In this work, the effects of Inter-symbol Interference (ISI) and light interference on Artificial Neural Network (ANN) receiver are analyzed and reported. In proposed optical wireless system the On- Off Keying (OOK) modulation is used at receiver to analyze BER and SNR. It is further concluded that error prospect in the received signal relates to the noise level, which is given in terms of obtained SNR value.
Crystal structure of ethyl (E)-5-((2-(3-hydroxybenzoyl)hydrazono)methyl)-3,4-dimethyl-1H-pyrrole-2-carboxylate – water – ethanol (1/1/1), C19H27N3O6
Authors: Lv Liangjun , Hao Zhengli , Lin Long , Wang Yuan 
Published: December 2017

Abstract
C19H27N3O6, monoclinic, P21/c (no. 14), a = 8.132(7) Å, b = 8.762(7) Å, c = 30.22(3) Å, β = 97.19(2)°, V = 2136(3) Å3, Z = 4, R
gt(F) = 0.0579, wR
ref(F
2) = 0.1892, T = 296(2) K.
Stability Study of Morphine and Baclofen Solution in Polypropylene Syringes
Authors: Robert Julien , Sorrieul Jérémy , Kieffer Hélène , Folliard Caroline , Gibory Vincent , Dupoiron Denis , Devys Catherine 
Published: December 2017

AbstractBackgroundThe association of morphine and baclofen is used for the treatment of spasticity related pain. Moving these patients is sometimes difficult. In order to transport these syringes for pump refilling, it could be interesting to demonstrate the stability of the mixture, and so to be able to ensure the best transport conditions of syringes.MethodsA stability indicating UPLC-DAD method was developed and validated according to the ICH guidelines. Two mixtures of morphine and baclofen – a low concentration mixture (morphine 1 mg/mL – baclofen 0.08 mg/mL) and a high concentration mixture (morphine 10 mg/mL – baclofen 1.6 mg/mL) stored in 5±3 °C and 25±2 °C were evaluated for seven days and compared to the initial observed concentrations.ResultsThe stability of the low and high mixture is demonstrated for both storage conditions for seven days thanks to relative concentrations (95 % confidence intervals of the mean of 3 samples) systematically positioned between 95 % and 105 %. No degradation product was observed during the stability study.ConclusionThis study shows the stability of a weakly concentrated mixture and a highly concentrated mixture of morphine and baclofen. Extrapolation of these data to an intermediate mixture may be considered. Further studies will support this hypothesis. This result will allow the transport of the preparation under optimal conditions. Advance preparations for intrathecal pump refills could also be feasible.
Nordkoreas Raketenprogramm – Bedrohung oder Bluff?
Authors: Schmucker Robert H. , Schiller Markus 
Published: December 2017

Kurzfassung:
Die verstärkten nordkoreanische Raketentests halten seit 2014 zusammen mit Kernwaffentests und wüsten Drohungen die Welt in Atem. Doch wie fortgeschritten ist das nordkoreanische Raketenprogramm tatsächlich? Die hier vorgelegte Analyse kommt zu dem Ergebnis, dass es in Nordkorea kein nennenswertes eigenständiges Raketenprogramm gibt und dass alle Raketen, die das Land seit einigen Jahren vermehrt abgeschossen hat, offenkundig aus dem Ausland stammen und zwar praktisch ausschließlich aus dem Gebiet der ehemaligen Sowjetunion und aus China. Dieser Befund macht eine grundsätzliche politische Neubewertung der derzeitigen Krise notwendig und zwar sowohl was die reale Bedrohung durch Nordkoreas Raketenwaffen betrifft als auch mit Blick auf die politische Rolle Moskaus und Pekings.
Trumps Staatsdemontage. Hinter vermeintlichem Chaos betreibt die US-Regierung einen strategischen Umbau des Staates
Authors: Braml Josef 
Published: December 2017

Kurzfassung:
US-Präsident Trumps Handeln wirkt auf viele Beobachter impulsiv und erratisch. Dennoch zeigt es in seiner vermeintlichen Inkohärenz eine klare Linie und ein klares Ziel: Es geht darum, die Rolle des Staates in den USA radikal zu beschneiden. Der Artikel zeichnet die wesentlichen Stationen der Versuche der Trump-Administration nach, auf Bundesebene zu einer deutlichen Verringerung der Staatstätigkeit und zum Abbau von Regulierung zu schreiten und zudem die Steuern zu senken. Die Folgen werden tiefgehend sein. Sie werden zu einer abnehmenden Handlungsfähigkeit des Bundesstaates führen und dessen Verschuldung weiter anheben. Zudem sind nachhaltige Folgen für die internationalen Finanzbeziehungen und den internationalen Handel zu befürchten.
Schnelle Lufttemperaturfühler zur Anwendung in der Präzisionsmesstechnik und Maschinenkalibrierung
Authors: Schüler Ralf , Mammen Helge , Mengs Enrico , Schalles Marc , Fröhlich Thomas 
Published: December 2017

Zusammenfassung
Um die Genauigkeit und Dynamik der Lufttemperaturmessung speziell für Anwendungen in der Interferometrie und
Maschinenkalibrierung zu verbessern, wurde ein neuer hochdynamischer Temperaturfühler in zwei Varianten entwickelt. Der
neue Sensor basiert auf einem drahtgewickelten Pt100-Sensor, der keine Richtungsabhängigkeit in den
dynamischen Eigenschaften aufweist und in einem feuchten Medium kalibriert werden kann. Es gibt zwei Varianten: einen
hochdynamischen Sensor und einen robusteren Sensor mit nur wenig schlechteren dynamischen Eigenschaften. Um die
Genauigkeit zu steigern, wurde der Sensor mit einer integrierten Messelektronik ausgestattet, die eine Kalibrierung der
ganzen Messkette in einem Zug erlaubt. Eine Klimamessstation für 15 drahtgebundene und 15 Funkfühler ist
verfügbar. Die folgenden Parameter wurden erreicht: t
63 = 4.3 s, Messintervall ≥ 0.9 s,
Auf”-lösung: 0.1 mK (drahtgebunden), 1 mK (drahtlos), Genauigkeit: typisch ±50 mK
(abhängig von der Kalibrierung). Weitere Anwendungsgebiete sind z. B. die Überwachung und Qualifizierung von Messräumen,
Klimakammern und Messaufbauten.
A Computational Account of Optimizing Social Predictions Reveals That Adolescents Are Conservative Learners in Social Contexts
Authors: Rosenblau Gabriela , Korn Christoph W. , Pelphrey Kevin A. 
Published: December 2017

As adolescents transition to the complex world of adults, optimizing predictions about others' preferences becomes vital for successful social interactions. Mounting evidence suggests that these social learning processes are affected by ongoing brain development across adolescence. A mechanistic understanding of how adolescents optimize social predictions and how these learning strategies are implemented in the brain is lacking. To fill this gap, we combined computational modeling with functional neuroimaging. In a novel social learning task, male and female human adolescents and adults predicted the preferences of peers and could update their predictions based on trial-by-trial feedback about the peers' actual preferences. Participants also rated their own preferences for the task items and similar additional items. To describe how participants optimize their inferences over time, we pitted simple reinforcement learning models against more specific “combination” models, which describe inferences based on a combination of reinforcement learning from past feedback and participants' own preferences. Formal model comparison revealed that, of the tested models, combination models best described how adults and adolescents update predictions of others. Parameter estimates of the best-fitting model differed between age groups, with adolescents showing more conservative updating. This developmental difference was accompanied by a shift in encoding predictions and the errors thereof within the medial prefrontal and fusiform cortices. In the adolescent group, encoding of own preferences and prediction errors scaled with parent-reported social traits, which provides additional external validity for our learning task and the winning computational model. Our findings thus help to specify adolescent-specific social learning processes.SIGNIFICANCE STATEMENTAdolescence is a unique developmental period of heightened awareness about other people. Here we probe the suitability of various computational models to describe how adolescents update their predictions of others' preferences. Within the tested model space, predictions of adults and adolescents are best described by the same learning model, but adolescents show more conservative updating. Compared with adults, brain activity of adolescents is modulated less by predictions themselves and more by prediction errors per se, and this relationship scales with adolescents' social traits. Our findings help specify social learning across adolescence and generate hypotheses about social dysfunctions in psychiatric populations.
Prismatic Adaptation Modulates Oscillatory EEG Correlates of Motor Preparation but Not Visual Attention in Healthy Participants
Authors: Bracco Martina , Veniero Domenica , Oliveri Massimiliano , Thut Gregor 
Published: December 2017

Prismatic adaption (PA) has been proposed as a tool to induce neural plasticity and is used to help neglect rehabilitation. It leads to a recalibration of visuomotor coordination during pointing as well as to aftereffects on a number of sensorimotor and attention tasks, but whether these effects originate at a motor or attentional level remains a matter of debate. Our aim was to further characterize PA aftereffects by using an approach that allows distinguishing between effects on attentional and motor processes. We recorded EEG in healthy human participants (9 females and 7 males) while performing a new double step, anticipatory attention/motor preparation paradigm before and after adaptation to rightward-shifting prisms, with neutral lenses as a control. We then examined PA aftereffects through changes in known oscillatory EEG signatures of spatial attention orienting and motor preparation in the alpha and beta frequency bands. Our results were twofold. First, we found PA to rightward-shifting prisms to selectively affect EEG signatures of motor but not attentional processes. More specifically, PA modulated preparatory motor EEG activity over central electrodes in the right hemisphere, contralateral to the PA-induced, compensatory leftward shift in pointing movements. No effects were found on EEG signatures of spatial attention orienting over occipitoparietal sites. Second, we found the PA effect on preparatory motor EEG activity to dominate in the beta frequency band. We conclude that changes to intentional visuomotor, rather than attentional visuospatial, processes underlie the PA aftereffect of rightward-deviating prisms in healthy participants.SIGNIFICANCE STATEMENTPrismatic adaptation (PA) has been proposed as a tool to induce neural plasticity in both healthy participants and patients, due to its aftereffect impacting on a number of visuospatial and visuomotor functions. However, the neural mechanisms underlying PA aftereffects are poorly understood as only little neuroimaging evidence is available. Here, we examined, for the first time, the origin of PA aftereffects studying oscillatory brain activity. Our results show a selective modulation of preparatory motor activity following PA in healthy participants but no effect on attention-related activity. This provides novel insight into the PA aftereffect in the healthy brain and may help to inform interventions in neglect patients.
Detection of Epistasis for Flowering Time Using Bayesian Multilocus Estimation in a Barley MAGIC Population
Authors: Mathew Boby , Léon Jens , Sannemann Wiebke , Sillanpää Mikko J 
Published: December 2017

AbstractFlowering time is a well-known complex trait in crops and is influenced by many interacting genes. In this study, Mathew et al. identify two-way and....Gene-by-gene interactions, also known as epistasis, regulate many complex traits in different species. With the availability of low-cost genotyping it is now possible to study epistasis on a genome-wide scale. However, identifying genome-wide epistasis is a high-dimensional multiple regression problem and needs the application of dimensionality reduction techniques. Flowering Time (FT) in crops is a complex trait that is known to be influenced by many interacting genes and pathways in various crops. In this study, we successfully apply Sure Independence Screening (SIS) for dimensionality reduction to identify two-way and three-way epistasis for the FT trait in a Multiparent Advanced Generation Inter-Cross (MAGIC) barley population using the Bayesian multilocus model. The MAGIC barley population was generated from intercrossing among eight parental lines and thus, offered greater genetic diversity to detect higher-order epistatic interactions. Our results suggest that SIS is an efficient dimensionality reduction approach to detect high-order interactions in a Bayesian multilocus model. We also observe that many of our findings (genomic regions with main or higher-order epistatic effects) overlap with known candidate genes that have been already reported in barley and closely related species for the FT trait.
Attention-Deficit/Hyperactivity Disorder and Very Preterm/Very Low Birth Weight: A Meta-analysis
Authors: Franz Adelar Pedro , Bolat Gul Unsel , Bolat Hilmi , Matijasevich Alicia , Santos Iná Silva , Silveira Rita C. , Procianoy Renato Soibelmann , Rohde Luis Augusto , Moreira-Maia Carlos Renato 
Published: December 2017

CONTEXT:
Although very preterm (VP), extremely preterm (EP), very low birth weight (VLBW), and extremely low birth weight (ELBW) newborns seem to have a higher risk of later attention-deficit/hyperactivity disorder (ADHD), the magnitude of the risk is not well-defined.

OBJECTIVE:
To systematically review and meta-analyze the risk of VP/VLBW and EP/ELBW individuals to develop a ADHD categorical diagnosis or dimensional symptomatology compared with controls with normal weight and/or birth age.

DATA SOURCES:
We used PsycINFO, Medline, Embase, and Cochrane databases.

STUDY SELECTION:
We selected cross-sectional, prospective, or retrospective studies with no time or language restriction.

DATA EXTRACTION:
Independent reviewers screened and extracted data using predefined standard procedures.

RESULTS:
In 12 studies (N = 1787), researchers relying on a categorical diagnosis showed that both VP/VLBW and EP/ELBW subjects have a higher ADHD risk (odds ratio [OR] = 3.04 higher than controls; 95% confidence interval [CI] 2.19 to 4.21). In subgroup analyses, we demonstrated that the more extreme the cases, the higher the ORs (VP/VLBW: OR = 2.25 [95% CI 1.56 to 3.26]; EP/ELBW: OR = 4.05 [95% CI 2.38 to 6.87]). We drew data from 29 studies (N = 3504) on ADHD symptomatology and found significant associations with inattention (standardized mean difference [SMD] = 1.31, 95% CI 0.66 to 1.96), hyperactivity and impulsivity (SMD = 0.74, 95% CI 0.35 to 1.13), and combined symptoms (SMD = 0.55, 95% CI 0.42 to 0.68) when compared with controls.

LIMITATIONS:
Heterogeneity was significantly high for all analyses involving the 3 ADHD dimensions.

CONCLUSIONS:
With our results, we provide evidence that VP/VLBW subjects have an increased risk of ADHD diagnosis and symptomatology compared with controls, and these findings are even stronger in the EP/ELBW group. Future researchers should address which risk factors related to prematurity or low birth weight lead to ADHD.
Az akut vestibularis szindróma sürgősségi diagnosztikájával szerzett tapasztalatok
Authors: Tamás T. László , Garai Tibor , Király István , Mike Andrea , Nagy Csaba , Paukovics Ágnes , Schmidt Péter , Szatmári Ferenc , Tompos Tamás , Vadvári Árpád , Szirmai Ágnes 
Published: December 2017

Abstract: Introduction and aim: To diagnose acute vestibular syndrome (AVS) in a prospective study by a new bedside test (providing 1A evidence) based on oculomotor analysis and assessment of hearing loss. To assess the frequency of central and peripheral causes of acute vestibular syndrome in the emergency room. To establish the diagnostic accuracy of acute cranial computed tomography as compared to oculomotor analysis done by video oculography goggles and audiometry. Method: Between 1st March 2016 and 1st March 2017 we documented 125 patients (62 women, 63 men, average age 53 years) in the emergency room of the Petz Aladár County Teaching Hospital using the above bedside and instrumental testing. Diagnosis was verified by cranial magnetic resonance imaging. Results: According to the results of the instrumental examination in AVS in 67% we found a peripheral cause and in 33% a central pathology. In 62% isolated posterior circulation stroke manifested itself by isolated vertigo without additional focal signs and the acute cranial computed tomography showed negative results in 96%. The instrumental examination increased diagnostic accuracy by making the diagnosis of isolated inferior semicircular canal vestibular neuritis possible. Conclusions: The new bedside oculomotor test is suitable for the diagnosis of posterior circulation stroke manifesting with isolated vertigo in early cases, when the routine neuroradiologic methods have a lower sensitivity or are not available. Orv Hetil. 2017; 158(51): 2029–2040.
Refleksja pastoralnoteologiczna nad dokumentem Stolicy Apostolskiej „Przyjęcie Chrystusa w uchodźcach i przymusowo przesiedlonych”
Authors: Ostrowski Maciej 
Published: December 2017

Autor analizuje i komentuje mało znany dokument wydany przez Stolicę Apostolska. Skupia się na teologicznych wątkach zawartych w dokumencie, pomijając inne kwestie w nim zawarte. Zwraca uwagę na konieczność odróżnienia migrantów przymusowo wysiedlonych i uchodźców od innych kategorii, np. migrantów ekonomicznych. Wskazuje na teksty biblijne i te elementy społecznej nauki Kościoła, na które powołują się redaktorzy dokumentu, wzywając do przyjmowania i otoczenia troską uchodźców oraz przymusowo przesiedlonych. Wśród nich na pierwsze miejsce wysuwa się nauczanie o godności każdej ludzkiej osoby, o jedności całej ludzkiej rodziny, o naśladowaniu miłości Boga do każdego człowieka, o chrześcijańskiej gościnności. Najistotniejszym ewangelicznym motywem przyjmowania obcych jest rozpoznanie w nich osoby samego Chrystusa. Motywy te znajdują zatem najgłębsze uzasadnienie w wierze i są jej praktyczną weryfikacją. W komentarzach do fragmentów dokumentu autor odnosi się do charakterystycznych współczesnych sytuacji związanych z przyjmowaniem migrantów, odczytując je w teologicznym świetle, a w konkluzji formułuje kilka pastoralnych wskazań dla Kościoła.