bluuebunny/crossref_metadata_2025_split huggingface dataset:
The integrated hydrologic model intercomparison project, IH‐MIP2: A second set of benchmark results to diagnose integrated hydrology and feedbacks
Authors: Kollet Stefan , Sulis Mauro , Maxwell Reed M. , Paniconi Claudio , Putti Mario , Bertoldi Giacomo , Coon Ethan T. , Cordano Emanuele , Endrizzi Stefano , Kikinzon Evgeny , Mouche Emmanuel , Mügler Claude , Park Young‐Jin , Refsgaard Jens C. , Stisen Simon , Sudicky Edward 
Published: December 2016

AbstractEmphasizing the physical intricacies of integrated hydrology and feedbacks in simulating connected, variably saturated groundwater‐surface water systems, the Integrated Hydrologic Model Intercomparison Project initiated a second phase (IH‐MIP2), increasing the complexity of the benchmarks of the first phase. The models that took part in the intercomparison were ATS, Cast3M, CATHY, GEOtop, HydroGeoSphere, MIKE‐SHE, and ParFlow. IH‐MIP2 benchmarks included a tilted v‐catchment with 3‐D subsurface; a superslab case expanding the slab case of the first phase with an additional horizontal subsurface heterogeneity; and the Borden field rainfall‐runoff experiment. The analyses encompassed time series of saturated, unsaturated, and ponded storages, as well as discharge. Vertical cross sections and profiles were also inspected in the superslab and Borden benchmarks. An analysis of agreement was performed including systematic and unsystematic deviations between the different models. Results show generally good agreement between the different models, which lends confidence in the fundamental physical and numerical implementation of the governing equations in the different models. Differences can be attributed to the varying level of detail in the mathematical and numerical representation or in the parameterization of physical processes, in particular with regard to ponded storage and friction slope in the calculation of overland flow. These differences may become important for specific applications such as detailed inundation modeling or when strong inhomogeneities are present in the simulation domain.
Global evaluation of new GRACE mascon products for hydrologic applications
Authors: Scanlon Bridget R. , Zhang Zizhan , Save Himanshu , Wiese David N. , Landerer Felix W. , Long Di , Longuevergne Laurent , Chen Jianli 
Published: December 2016

AbstractRecent developments in mascon (mass concentration) solutions for GRACE (Gravity Recovery and Climate Experiment) satellite data have significantly increased the spatial localization and amplitude of recovered terrestrial Total Water Storage anomalies (TWSA); however, land hydrology applications have been limited. Here we compare TWSA from April 2002 through March 2015 from (1) newly released GRACE mascons from the Center for Space Research (CSR‐M) with (2) NASA JPL mascons (JPL‐M), and with (3) CSR Tellus gridded spherical harmonics rescaled (sf) (CSRT‐GSH.sf) in 176 river basins, ∼60% of the global land area. Time series in TWSA mascons (CSR‐M and JPL‐M) and spherical harmonics are highly correlated (rank correlation coefficients mostly >0.9). The signal from long‐term trends (up to ±20 mm/yr) is much less than that from seasonal amplitudes (up to 250 mm). Net long‐term trends, summed over all 176 basins, are similar for CSR and JPL mascons (66–69 km3/yr) but are lower for spherical harmonics (∼14 km3/yr). Long‐term TWSA declines are found mostly in irrigated basins (−41 to −69 km3/yr). Seasonal amplitudes agree among GRACE solutions, increasing confidence in GRACE‐based seasonal fluctuations. Rescaling spherical harmonics significantly increases agreement with mascons for seasonal fluctuations, but less for long‐term trends. Mascons provide advantages relative to spherical harmonics, including (1) reduced leakage from land to ocean increasing signal amplitude, and (2) application of geophysical data constraints during processing with little empirical postprocessing requirements, making it easier for nongeodetic users. Results of this product intercomparison should allow hydrologists to better select suitable GRACE solutions for hydrologic applications.
The Acculturation of Community Psychology: Is There a Best Way?
Authors: Birman Dina 
Published: December 2016

AbstractIn this paper I describe a community psychology perspective on acculturation and adjustment of immigrants and refugees and suggest that this field of acculturation research has in turn something to offer heuristically as we consider our identity and training for future generations of community psychologists over the next 50 years. I suggest that honoring our heritage, maintaining our disciplinary identity as community psychologists, and sustaining doctoral programs that offer training specific to community psychology are crucial for our survival as a field and is not antithetical to, and is indeed necessary for, interdisciplinary collaborations.
Eine Gesamtproteom‐basierte Auflistung der Hintergrundbinder von Photovernetzern
Authors: Kleiner Philipp , Heydenreuter Wolfgang , Stahl Matthias , Korotkov Vadim S. , Sieber Stephan A. 
Published: December 2016

AbstractAffinitäts‐basiertes Protein‐Profiling (AfBPP) wird weithin zur Identifizierung der Zielproteine bioaktiver Moleküle eingesetzt. Sonden, die Photovernetzer wie Benzophenone, Diazirine und Arylazide enthalten, binden nach UV‐Bestrahlung das Molekül irreversibel an dessen Zielprotein. Bisher ist jedoch nur wenig über Photovernetzer‐spezifische Off‐Targets bekannt, was die Zuverlässigkeit der Ergebnisse einschränkt. Hier wurde deshalb der Proteinhintergrund von Photovernetzern mittels Gel‐freier, quantitativer Proteomik bestimmt. Für jede photoreaktive Gruppe wurden die charakteristischen Off‐Targets identifiziert. Um die Bedeutung der Ergebnisse zu verdeutlichen, wurde H8, ein Inhibitor der Proteinkinase A, mit einer Diazirin‐Einheit modifiziert. Der Vergleich des identifizierten Diazirin‐Hintergrunds mit den erhaltenen Zielproteinen dieser Photosonde lieferte neue Einblicke in deren In‐situ‐Zielproteine. Die Ergebnisse sind wegweisend für die Identifizierung biologisch relevanter Bindungspartner in Experimenten, in denen Photosonden verwendet werden.
Energy‐Saving Electrolytic Hydrogen Generation: Ni2P Nanoarray as a High‐Performance Non‐Noble‐Metal Electrocatalyst
Authors: Tang Chun , Zhang Rong , Lu Wenbo , Wang Zao , Liu Danni , Hao Shuai , Du Gu , Asiri Abdullah M. , Sun Xuping 
Published: December 2016

AbstractIt is highly attractive but challenging to develop earth‐abundant electrocatalysts for energy‐saving electrolytic hydrogen generation. Herein, we report that Ni2P nanoarrays grown in situ on nickel foam (Ni2P/NF) behave as a durable high‐performance non‐noble‐metal electrocatalyst for hydrazine oxidation reaction (HzOR) in alkaline media. The replacement of the sluggish anodic oxygen evolution reaction with such the more thermodynamically favorable HzOR enables energy‐saving electrochemical hydrogen production with the use of Ni2P/NF as a bifunctional catalyst for anodic HzOR and cathodic hydrogen evolution reaction. When operated at room temperature, this two‐electrode electrolytic system drives 500 mA cm−2 at a cell voltage as low as 1.0 V with strong long‐term electrochemical durability and 100 % Faradaic efficiency for hydrogen evolution in 1.0 m KOH aqueous solution with 0.5 m hydrazine.
A Robust and Broadly Applicable Cobalt‐Catalyzed Cross‐Coupling of Functionalized Bench‐Stable Organozinc Pivalates with Unsaturated Halides
Authors: Hammann Jeffrey M. , Lutter Ferdinand H. , Haas Diana , Knochel Paul 
Published: December 2016

AbstractWe report a robust and broadly applicable CoCl2‐catalyzed cross‐coupling between functionalized aryl and heteroaryl zinc pivalates and various electron‐poor aryl and heteroaryl halides (X=Cl, Br, I). Couplings with (E)‐ or (Z)‐bromo‐ or iodo‐alkenes proceed with retention of configuration. Also, alkynyl bromides react with arylzinc pivalates providing arylated alkynes.
Circle of Security Intervention for Parents of Children with Autism Spectrum Disorder
Authors: Fardoulys Claire , Coyne Joe 
Published: December 2016

Circle of Security is an attachment‐based parenting intervention that aims to promote secure parent–child attachment relationships. The current study explored whether the Circle of Security intensive intervention resulted in increased attachment security (assessed before and after completing the intervention) for caregiver–child dyads with Autism Spectrum Disorder. The current study also explored caregivers’ acceptance of the intervention by seeking client feedback and measured each caregiver's perceived sense of parenting competence. Two mothers each with a child under the age of 5 years diagnosed with Autistic Spectrum Disorder participated in the intervention. Results found one dyad shifted from avoidant to secure whilst the other dyad remained secure across time with some changes in behavioural dimensions. Each mother endorsed the intervention as highly valuable to her needs. Perceived parenting competence also increased post‐intervention for both mothers. Replication is recommended in order to generalise the results.
The Value of Complementarity. Integrating the Evidence from Air Survey and ALS in Bohemia
Authors: Gojda Martin 
Published: December 2016

AbstractThis paper offers a contribution to discussion of the value of integrating different airborne perspectives for landscape prospection. A case study in Bohemia, Czech Republic, illustrates how the integration of the results of a long‐term programme of aerial reconnaissance and recently acquired airborne laser scanning (ALS) (LiDAR) data has significantly improved the methodology and knowledge dividend for the study of past landscapes and settlements. Three types of features – barrows/ring ditches, a hillfort, and a nineteenth century artillery redoubts – have been surveyed repeatedly in order to detect the degree to which sites known from differential cropmarking in arable crops are also evident in ALS‐derived digital terrain models (DTMs), and vice versa. It is noted that components of the hillfort and redoubts are clearly evident in the DTMs despite lying in fields that have been intensively cultivated for many decades at least, and are not easily recognized from the ground because their outline is so smoothed. This study illustrates the complementarities of cropmark aerial survey and ALS even in heavily ploughed environments, where there is often an assumption that features recorded as cropmarks have no surface expression, when in fact this often depends on the scale of the features. Copyright © 2016 John Wiley & Sons, Ltd.
Realization of Actuator‐Fault Estimation for Distributed Wireless Networked Control Systems
Authors: Xu Dongmei , Wang Ying , Zhang Liping 
Published: December 2016

AbstractThis paper addresses a study of fault estimation for distributed wireless networked control systems (WNCSs) with actuator multiple faults during industrial automatic processes. Firstly, the model of WNCSs is formulated as linear time periodic systems (LTPSs) according to the periodicity of subsystems in WNCSs. Afterwards, the distributed fault estimation (FE) method for LTPSs is concerned. The strategy of avoiding the problem of structure‐limitation in the FE gain and the realization of the proposed method in the real process are especially detailed. Finally, the proposed FE method is verified on a wireless network control (WiNC) platform.
Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions
Authors: Nicolas Jean‐Marie , Bouzom François , Hugues Chanteux , Ungell Anna‐Lena 
Published: December 2016

AbstractThe dissolution, intestinal absorption and presystemic metabolism of a drug depend on its physicochemical characteristics but also on numerous physiological (e.g. gastrointestinal pH, volume, transit time, morphology) and biochemical factors (e.g. luminal enzymes and flora, intestinal wall enzymes and transporters). Over the past decade, evidence has accumulated indicating that these factors may differ in children and adults resulting in age‐related changes in drug exposure and drug response. Thus, drug dosage may require adjustment for the pediatric population to ensure the desired therapeutic outcome and to avoid side‐effects. Although tremendous progress has been made in understanding the effects of age on intestinal physiology and function, significant knowledge gaps remain. Studying and predicting pharmacokinetics in pediatric patients remains challenging due to ethical concerns associated with clinical trials in this vulnerable population, and because of the paucity of predictive in vitro and in vivo animal assays. This review details the current knowledge related to developmental changes determining intestinal drug absorption and pre‐systemic metabolism. Supporting experimental approaches as well as physiologically based pharmacokinetic modeling are also discussed together with their limitations and challenges. © 2016 UCB Biopharma sprl. Biopharmaceutics & Drug Disposition Published by John Wiley & Sons, Ltd.
Autophagy and the endo/exosomal pathways in health and disease
Authors: Papandreou Margarita‐Elena , Tavernarakis Nektarios 
Published: December 2016

AbstractCell homeostasis requires the concerted action of cellular pathways involved in degradation, trafficking and intercellular communication, which are interlinked to satisfy the cell's needs upon demand. Defects in these pathways instigate the development of several age‐related pathologies, such as neurodegenerative and chronic inflammatory diseases. Autophagy is an evolutionarily conserved and tightly regulated process of degrading cellular constituents. The endosomal and vesicular trafficking pathways contribute to this regulation and share common features with the autophagic process. Recently, autophagy has been implicated in the endosome/exosome secretory pathway. Importantly, current technological advances allow the manipulation of exosomes as drug nanocarriers in pharmaceutical intervention strategies. Here, we survey emerging findings relevant to the crosstalk between autophagy and the endo/exosomal vesicular trafficking pathways. In addition, we discuss novel methodologies that have recently been developed, which allow the utilization of these pathways for targeted drug delivery in disease.
Optimization of enzymatic hydrolysis and fermentation conditions for improved bioethanol production from potato peel residues
Authors: Ben Taher Imen , Fickers Patrick , Chniti Sofien , Hassouna Mnasser 
Published: December 2016

The aim of this work was the optimization of the enzyme hydrolysis of potato peel residues (PPR) for bioethanol production. The process included a pretreatment step followed by an enzyme hydrolysis using crude enzyme system composed of cellulase, amylase and hemicellulase, produced by a mixed culture of Aspergillus niger and Trichoderma reesei. Hydrothermal, alkali and acid pretreatments were considered with regards to the enhancement of enzyme hydrolysis of potato peel residues. The obtained results showed that hydrothermal pretreatment lead to a higher enzyme hydrolysis yield compared to both acid and alkali pretreatments. Enzyme hydrolysis was also optimized for parameters such as temperature, pH, substrate loading and surfactant loading using a response surface methodology. Under optimized conditions, 77 g L−1 of reducing sugars were obtained. Yeast fermentation of the released reducing sugars led to an ethanol titer of 30 g L−1 after supplementation of the culture medium with ammonium sulfate. Moreover, a comparative study between acid and enzyme hydrolysis of potato peel residues was investigated. Results showed that enzyme hydrolysis offers higher yield of bioethanol production than acid hydrolysis. These results highlight the potential of second generation bioethanol production from potato peel residues treated with onsite produced hydrolytic enzymes. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:397–406, 2017
Investigation of Carbon Nanotubes in Mixed Matrix Membranes for Gas Separation: A Review
Authors: Nejad Mahsa Nahavandi , Asghari Morteza , Afsari Morteza 
Published: December 2016

AbstractMixed matrix membranes (MMM) consist of a polymeric base with additive fillers. Zeolites, carbon molecular sieves, graphene and carbon nanotubes (CNTs) are most commonly used fillers in the development of MMMs. Among these materials, CNTs have been proposed recently for gas separation application due to their attractive properties. Although CNTs have excellent separation properties, preparation of CNT‐MMMs is more complicated. To employ CNTs as effective reinforcement in the polymeric matrix, proper dispersion and suitable interfacial adhesion between the CNTs and the polymer matrix have to be guaranteed. In this paper, recent advances and developments on CNTs dispersion and alignment in the matrix were reviewed. Also, a critical comparison of various CNT functionalization methods and different functional groups are given. Applications of CNT‐MMMs in gas separation are also reviewed.
From Biogas to Biofuel: Materials Used for Biogas Cleaning to Biomethane
Authors: Chaemchuen Somboon , Zhou Kui , Verpoort Francis 
Published: December 2016

AbstractBiomethane is one of the biofuel sources produced from biogas which is an important source of renewable energy. Since it is an alternative and clean energy source, its implementation as fuel source applying established energy infrastructure is an attractive opportunity. However, biogas as a source of biomethane contains undesirable compounds, e.g., H2S, NH3, siloxanes, water, etc. and needs to be decontaminated before usage. Biogas cleaning technologies are presented from a material point of view along with their property modifications. A brief discussion of materials applied in technologies with a particular emphasis on biogas cleaning is followed by the alternative properties and possibilities of liquid and solid adsorbents as well as chemical reactions used for biogas cleaning to produce biomethane suitable as fuel source to replace or reduce fossil fuel consumption.
Radioactive seed localization of renal cell carcinoma in a patient with Von Hippel‐Lindau disease
Authors: Hassing Christina Marie Schiøttz , Tvedskov Tove Filtenborg , Kroman Niels , Klausen Thomas Levin , Djurhuus Sissal , Langhans Linnea 
Published: December 2016

Key Clinical MessageThis report describes the case of a patient, who had successful radioactive seed localization (RSL) performed to improve the identification and excision of a renal cell carcinoma. RSL is a new method of preoperative localization, which can ease the surgical procedure, minimize tissue trauma, and ultimately benefit the patient.
Successful outcome of three patients with sickle‐cell disease and fat embolism syndrome treated with intensive exchange transfusion
Authors: Greaves Paul , Mathew Vivek , Peters Catherine , Rowe Susan , Amos Roger J. , Tsitsikas Dimitris A. 
Published: December 2016

Key Clinical MessageFat embolism syndrome (FES) is a rare complication of sickle‐cell disease (SCD) associated with extremely high mortality rates. It affects predominantly non‐SS patients and those with previously mild disease. Rapid institution of exchange transfusion with an aim to reduce HbS to very low levels as soon as FES is suspected can be life‐saving.
Arylation of N‐Methyl‐2‐oxindole with Arylboronic Acids in Water Catalyzed by Palladium(II) Pincer Complexes with a Low Catalyst Loading
Authors: Vignesh Arumugam , Kaminsky Werner , Dharmaraj Nallasamy 
Published: December 2016

AbstractTwo new PdII ONO pincer complexes were utilized efficiently as homogeneous catalysts for the site‐selective C3‐arylation of N‐methyl‐2‐oxindole with arylboronic acids at room temperature in aqueous media to yield a series of 3‐aryl‐N‐methyl‐2‐oxindoles. This catalytic reaction progressed well with a low catalyst loading (0.01 mol %) under open‐flask conditions. Notably, a column‐chromatography‐free method for the quantitative preparation of C3‐arylated N‐methyl‐2‐oxindoles is reported. The catalyst showed good compatibility with wide range of substrates with recyclability in up to five consecutive runs without an appreciable loss of yield.
Synthesis, Crystal Structure, and Properties of Bi3TeBO9 or Bi3(TeO6)(BO3): A Non‐Centrosymmetric Borate–Tellurate(VI) of Bismuth
Authors: Daub Michael , Krummer Michael , Hoffmann Anke , Bayarjargal Lkhamsuren , Hillebrecht Harald 
Published: December 2016

AbstractPale‐yellow single crystals of the new borate tellurate(VI) Bi3TeBO9 were obtained by reaction of stoichiometric amounts of Bi2O3, B2O3, and Te(OH)6 at 780 °C. The non‐centrosymmetric crystal structure (P63, Z=2, a=8.7454(16), c=5.8911(11) Å, 738 refl., 43 param, R1=0.037, wR2=0.093) contains isolated trigonal‐planar BO3 units and nearly undistorted TeO6 octahedra. The Bi3+ cations are located in between in octahedral voids. The BiO6 octahedra are significantly distorted to a [3+3] pattern (2.25/2.50 Å) due to the ns2 configuration. According to the structural features, the formula can be written as Bi3(TeO6)(BO3). Alternatively, the structure can also be described as hcp of oxygen with TeVI and BiIII in octahedral voids and BIII in trigonal‐ planar voids. The vibrational spectra show the typical features of BO3 and TeO6 units with a significant 10B/11B isotopic splitting of the IR‐active B−O valence mode (1248 and 1282 cm−1). The UV/Vis spectrum shows an optical band edge with an onset around 480 nm (2.6 eV). MAS‐NMR spectra of 11B show an anisotropic signal with a quadrupole coupling constant of CQ=2.55 MHz. and a very small deviation from rotational symmetry (η=0.2). The isotropic chemical shift is 20.1 ppm. The second harmonic generation (SHG) test was positive with an activity comparable to potassium dihydrogen phosphate (KDP). Bi3TeBO9 decomposes in air at 825 °C to Bi2TeO5.
Bicyclo[3.2.0]heptane as a Core Structure for Conformational Locking of 1,3‐Bis‐Pharmacophores, Exemplified by GABA
Authors: Vorberg Raffael , Trapp Nils , Carreira Erick M. , Müller Klaus 
Published: December 2016

AbstractThe synthesis and X‐ray crystal structures of syn and anti 4‐N‐Boc‐aminobicyclo[3.2.0]heptane‐1‐carboxylic acids are described. The placement of the N‐Boc‐amino groups in the two stereoisomers in either pseudo‐equatorial or pseudo‐axial positions renders the molecules conformationally locked, with N‐Boc‐protected γ‐aminobutyric acid (GABA) embedded within the bicyclic core. Despite the different conformations of the urethane and distinct crystal packing, the bicyclic core units of the two stereoisomers adopt virtually identical structures. They correspond to in silico models of the parent bicyclic core and a systematic array of disubstituted derivatives. The study documents an intrinsic property of the bicyclo[3.2.0]heptane core to favor adoption of a boat‐like conformation, which is largely unaffected by various substitution patterns. The structural concepts are useful in the design of molecules with spatial and directional fixation of pharmacophoric groups.
Detailed Structural Analysis of a Self‐Assembled Vesicular Amphiphilic NCN‐Pincer Palladium Complex by Wide‐Angle X‐Ray Scattering and Molecular Dynamics Calculations
Authors: Hamasaka Go , Muto Tsubasa , Andoh Yoshimichi , Fujimoto Kazushi , Kato Kenichi , Takata Masaki , Okazaki Susumu , Uozumi Yasuhiro 
Published: December 2016

AbstractInvited for the cover of this issue are the groups of Susumu Okazaki and Yasuhiro Uozumi at the University of Nagoya and at Institute for Molecular Science in Okazaki, respectively. The image depicts an amphiphilic pincer complex, which, as if it has intelligence, self‐constructs vesicular architecture to gain catalytic properties. Read the full text of the article at 10.1002/chem.201603494.