bluuebunny/crossref_metadata_2025_split huggingface dataset:
Behavioural intention to adopt mobile banking among the millennial generation
Authors: Tan Evon , Leby Lau Jasmine 
Published: June 2016

PurposeThe purpose of this paper was to examine the intention to adopt mobile banking services among Generation Y consumers using the unified theory of acceptance and use of technology Unified Theory of Acceptance and Use of Technology (UTAUT) model.Design/methodology/approachThe paper investigated responses from a particular sub-group of Generation Y consumers that is college or university students. The final sample collected was 347 cases, representing a response rate of 90.4 per cent. Two sets of analyses were performed: multiple regression analyses testing the extended UTAUT model and a mediated regression analysis testing the intervening effect of performance expectancy (PE) on the relationship between effort expectancy (EE) and behavioural intention.FindingsMultiple regression analysis revealed PE as the strongest predictor, followed by EE, perceived risk and social influence. The prediction model explained 68.3 per cent of the variance in intention to adopt mobile banking. Mediation analysis supported a partial mediation effect of PE on the relationship between EE and intention to adopt mobile banking.Research limitations/implicationsThis study examined respondents’ intention to adopt mobile banking instead of their actual behaviour. Understanding behavioural intention is essential, but it may not accurately represent actual behaviour. In addition, results from this study may not be generalisable to the whole population of Generation Y college or university students due to selection bias and a lack of information concerning the sampling frame.Practical implicationsThis research identifies the factors that affect the intention to adopt mobile banking among the Generation Y college or university students. Bank operators can use the findings to improve their marketing strategies and services offered to make them more attractive and competitive to students to speed up the mobile banking adoption rate.Originality/valueThis study is one of the few local studies that introduce a practical model of extended UTAUT by including perceived risk to understand the mobile banking adoption intention among millennial generation.
Experiential value and domain-specific innovativeness during freemium game usage: effects on child well-being
Authors: Junior Ladeira Wagner , Oliveira de Santini Fernando , Hoffmann Sampaio Claudio , Araujo Clecio Falcao 
Published: June 2016

Purpose
In specifically examining uses of freemium applications for children, this study aims to investigate the effects on user well-being after the experiential value by examining the influence of experiential value in terms of domain-specific innovativeness; the impact of domain-specific innovativeness in terms of child well-being; the moderating role of child socialization; and the relevance of contextual variables associated with media exposure during freemium game use.

Design/methodology/approach
The study is based on a survey of children who had downloaded freemium games on their smartphones. A total of 410 completed questionnaires were collected from children of 9 to 12 years of age. Confirmatory factor analyses and structural equation models were applied to examine and test the study hypotheses.

Findings
The results indicate that experiential value influences domain-specific innovativeness; domain-specific innovativeness is a significant predictor of well-being; parental materialism and communication with friends significantly moderates domain-specific innovativeness and well-being; and contextual variables do not influence the model.

Practical implications
Public policy managers should be cognizant of these results and should make every effort to prevent the identified relationships from becoming too strong, given the strong effect of domain-specific innovativeness on child well-being.

Originality/value
This paper contributes to the extant literature by incorporating experiential value and domain-specific innovativeness variables within a comprehensive model and by accounting for the effects of relevant contextual variables and the moderating role of child socialization.
Studying long‐term, large‐scale grassland restoration outcomes to improve seeding methods and reveal knowledge gaps
Authors: Rinella Matthew J. , Espeland Erin K. , Moffatt Bruce J. 
Published: June 2016

Summary

Studies are increasingly investigating effects of large‐scale management activities on grassland restoration outcomes. These studies are providing useful comparisons among currently used management strategies, but not the novel strategies needed to rapidly improve restoration efforts. Here we illustrate how managing restoration projects adaptively can allow promising management innovations to be identified and tested.
We studied 327 Great Plains fields seeded after coal mining. We modelled plant responses to management strategies to identify the most effective previously used strategies for constraining weeds and establishing desired plants. Then, we used the model to predict responses to new strategies our analysis identified as potentially more effective.
Where established, the weed crested wheatgrass (Agropyron cristatum L.) increased through time, indicating a need to manage establishment of this grass. Seeding particular grasses reduced annual weed cover, and because these grasses appeared to become similarly abundant whether sown at low or high rates, low rates could likely be safely used to reduce seeding costs. More importantly, lower than average grass seed rates increased cover of shrubs, the plants most difficult to restore to many grassland ecosystems. After identifying grass seed rates as a driver, we formulated model predictions for rates below the range managers typically use. These predictions require testing but indicated atypically low grass seed rates would further increase shrubs without hindering long‐term grass stand development.
Synthesis and applications. Designing management around empirically based predictions is a logical next step towards improving ecological restoration efforts. Our predictions are that reducing grass seed rates to atypically low levels will boost shrubs without compromising grasses. Because these predictions derive from the fitted model, they represent quantitative hypotheses based on current understanding of the system. Generating data needed to test and update these hypotheses will require monitoring responses to shifts in management, specifically shifts to lower grass seed rates. A paucity of data for confronting hypotheses has been a major sticking point hindering adaptive management of most natural resources, but this need not be the case with degraded grasslands, because ongoing restoration efforts around the globe are providing continuous opportunities to monitor and manage processes regulating grassland restoration outcomes.
Phospholipid homeostasis maintains cell polarity, development and virulence in metarhizium robertsii
Authors: Gao Qiang , Lu Yuzhen , Yao Hongyan , Xu Yong‐Jiang , Huang Wei , Wang Chengshu 
Published: June 2016

SummaryThe final product of the glycerol phosphate (GP) pathway is triacylglycerol (TAG) that regulates the homeostasis of energy, fatty acids and phospholipids in cells. The enzymes involved in this pathway have been characterized in many model organisms; however, their contributions to fungal infection are largely unclear. In this study, we performed serial deletion of genes in the GP pathway in the insect pathogenic fungus Metarhizium robertsii. The results indicated that a lysophosphatidate acyltransferase mrLPAAT1 was required for fungal growth, cell differentiation, maintenance of cell polarity and virulence. Lipidomic analysis indicated that deletion of mrLPAAT1 resulted in significant increases in TAG, fatty acids and phosphatidylcholine (PC) but decreased phosphatidic acid (PA), phosphatidylethanolamine (PE) and other species of phospholipids when compared to the wild type. Disruption of the isozymatic gene mrLPAAT2, however, resulted in a reduction in PC but not PA in the mutant cells. There were no changes in development and virulence in ΔmrLPAAT2. Phospholipid feeding assays verified that a PE supplement could rescue the cell differentiation defect in ΔmrLPAAT1. The results of this study reveal that cellular phospholipid homeostasis mediated by the GP pathway regulates fungal growth, cell polarity, differentiation and virulence.
Trichothecenes and aspinolides produced by Trichoderma arundinaceum regulate expression of Botrytis cinerea genes involved in virulence and growth
Authors: Malmierca Mónica G. , Izquierdo‐Bueno Inmaculada , McCormick Susan P. , Cardoza Rosa E. , Alexander Nancy J. , Barua Javier , Lindo Laura , Casquero Pedro A. , Collado Isidro G. , Monte Enrique , Gutiérrez Santiago 
Published: June 2016

SummaryTrichoderma arundinaceum (Ta37) and Botrytis cinerea (B05.10) produce the sesquiterpenoids harzianum A (HA) and botrydial (BOT), respectively. TaΔTri5, an HA non‐producer mutant, produces high levels of the polyketide compounds aspinolides (Asp) B and C. We analyzed the role of HA and Asp in the B. cinerea‐T. arundinaceum interaction, including changes in BOT production as well as transcriptomic changes of BcBOT genes involved in BOT biosynthesis, and also of genes associated with virulence and ergosterol biosynthesis. We found that exogenously added HA up‐regulated the expression of the BcBOT and all the virulence genes analyzed when B. cinerea was grown alone. However, a decrease in the amount of BOT and a down‐regulation of BcBOT gene expression was observed in the interaction zone of B05.10‐Ta37 dual cultures, compared to TaΔTri5. Thus, the confrontation with T. arundinaceum results in an up‐regulation of most of the B. cinerea genes involved in virulence yet the presence of T. arundinaceum secondary metabolites, HA and AspC, act separately and together to down‐regulate the B. cinerea genes analyzed. The present work emphasizes the existence of a chemical cross‐regulation between B. cinerea and T. arundinaceum and contributes to understanding how a biocontrol fungus and its prey interact with each other.
The Structural Origins of Territorial Stigma: Water and Racial Politics in Metropolitan Detroit, 1950s–2010s
Authors: Kornberg Dana 
Published: June 2016

AbstractThis article develops the concept of territorial stigma by analyzing how it can be cultivated at the level of political institutions across administrative divides. I consider the case of Detroit's regional water department, which until 2016 was owned and operated by the city and served over 120 suburban regional municipalities. I start by examining the cooperative city–suburban water system expansion in the 1950s and then analyze the rise of Detroit's first black‐led administration in 1974, after which the water authority became a key regional institution that provided an opportunity for white suburban leaders to organize against the city. I find that suburban leaders advanced their immediate goal of mitigating rate hikes by declaring the city to be greedy and inept, instead of acknowledging structural conditions that increased operational costs. This had the effect of reproducing racialized stereotypes at the political level, which had enduring effects. The argument builds on the existing literature on territorial stigma by (1) identifying state institutions as sites for the propagation of stigma and (2) considering stigmatized places in relation to their non‐stigmatized neighbors. The analysis integrates material‐structural and cultural‐symbolic factors in order to understand the perpetuation of regional urban inequalities.
Why Local Social Forums Emerge Where They do: Beyond Diffusion, Geographical Appropriation
Authors: Dufour Pascale 
Published: June 2016

AbstractSocial forums are, quintessentially, a transnationally mobile institutional enterprise. Since the first World Social Forum in Porto Alegre, Brazil, in 2001, thousands of local initiatives have emerged all over the world. Yet we know very little about the diffusion processes involved. This article examines nine local social forums (LSFs) in two societies (France and Québec) in order to understand how social forums (SFs) spread throughout or within each territory. Aside from the usual factors, such as the presence or absence of an initiator, favorable political opportunity structure and access to resources, I consider the geography of appropriation, with an emphasis on the dimensions of place (where the forums are organized), and scales of action built by activists. First, I show that, as proposed in the social movement literature, SFs spread from the global South to the global North as a direct result of activists willing to reproduce within their localities that which they have seen and experienced on a larger scale. Political opportunity structures and access to resources appear relevant to understanding the longevity of LSFs and their capacity to be more or less encompassing experiences. But beyond these ‘usual suspects’, the geographical appropriation of social forums is an important consideration that helps us understand the specific diffusion of LSFs in each national territory. In Québec, the region is perceived as a ‘given’ by activists and becomes the relevant scale of collective action, while in France, scale building is at stake and LSFs are used as a tool to escape the centralization of the main national organization in the field of global protest.
A review of the available clinical therapies for vulvodynia management and new data implicating proinflammatory mediators in pain elicitation
Authors: Falsetta ML , Foster DC , Bonham AD , Phipps RP 
Published: June 2016

Localised provoked vulvodynia (LPV) is a common, chronic, and disabling condition: patients experience profound pain and a diminished quality of life. The aetiologic origins of vulvodynia are poorly understood, yet recent evidence suggests a link to site‐specific inflammatory responses. Fibroblasts isolated from the vestibule of LPV patients are sensitive to proinflammatory stimuli and copiously produce pain‐associated proinflammatory mediators (IL‐6 and PGE2). Although LPV is a multifactorial disorder, understanding vulvar inflammation and targeting the inflammatory response should lead to treatment advances, especially for patients exhibiting signs of inflammation. NFκB (already targeted clinically) or other inflammatory components may be suitable therapeutic targets.Tweetable abstractVulvodynia is a poorly understood, prevalent, and serious women's health issue requiring better understanding to improve therapy.
A midgut‐specific serine protease, BmSP36, is involved in dietary protein digestion in the silkworm, Bombyx mori
Authors: Liu Hua‐Wei , Li You‐Shan , Tang Xin , Guo Peng‐Chao , Wang Dan‐Dan , Zhou Chun‐Yan , Xia Qing‐You , Zhao Ping 
Published: June 2016

AbstractSerine proteases play important roles in digestion and immune responses during insect development. In the present study, the serine protease gene BmSP36, which encodes a 292‐residue protein, was cloned from the midgut cells of Bombyx mori. BmSP36 contains an intact catalytic triad (H57, D102 and S195) and a conserved substrate‐binding site (G189, H216 and G226), suggesting that it is a serine protease with chymotrypsin‐like specificity. The temporal and spatial expression patterns of BmSP36 indicated that its messenger RNA and protein expression mainly occurred in the midgut at the feeding stages. Western blotting, immunofluorescence and liquid chromatography‐tandem mass spectrometry analyses revealed secretion of BmSP36 protein from epithelial cells into the midgut lumen. The transcriptional and translational expression of BmSP36 was down‐regulated after starvation but up‐regulated after refeeding. Moreover, expression of the BmSP36 gene could be up‐regulated by a juvenile hormone analogue. These results enable us to better define the potential role of BmSP36 in dietary protein digestion at the feeding stages during larval development.
Is Regional Citrate Anticoagulation the Future of Hemodialysis?
Authors: Buturovic‐Ponikvar Jadranka 
Published: June 2016

AbstractCitrate has many characteristics of the ideal anticoagulant for hemodialysis. In addition to immediate and complete anticoagulation in the dialysis circuit, citrate has important effects beyond anticoagulation, mainly in reducing inflammatory response induced by hemodialysis. Citrate has already become the standard anticoagulant in acute kidney injury requiring continuous renal replacement therapy (CRRT), both for adults and children, with the citrate module being a part of modern CRRT monitors. Although the citrate module is not yet available for intermittent hemodialysis, precise infusion pumps, point‐of‐care ionometers and high citrate clearance from high flux dialyzers increase safety while reducing the risk of metabolic complications, both in adult and pediatric patients. Slovenia has a long tradition, high volume and expansion of citrate use in hemodialysis, including long‐term citrate anticoagulation in selected patients. At the Department of Nephrology, University Medical Centre Ljubljana, more than 10 000 citrate procedures were performed in 2015. We believe that regional citrate anticoagulation may replace heparin as the main anticoagulant for intermittent hemodialysis in the not so distant future.
Treatment of Antibody‐Mediated Rejection After Kidney Transplantation – 10 Years’ Experience With Apheresis at a Single Center
Authors: Gubensek Jakob , Buturovic‐Ponikvar Jadranka , Kandus Aljosa , Arnol Miha , Lindic Jelka , Kovac Damjan , Rigler Andreja Ales , Romozi Karmen , Ponikvar Rafael 
Published: June 2016

AbstractAntibody‐mediated rejection (AMR) is a major cause of kidney graft failure. We aimed to analyze treatment and outcome of AMR in a national cohort of 75 biopsy‐proven acute (43 patients, 57%) or chronic active (32 patients, 43%) AMR episodes between 2000 and 2015. The mean patients' age was 46 ± 16 years, the majority was treated with plasma exchange, 4% received immunoadsorption and 7% received both. The majority received pulse methylprednisolone and low‐dose CMV hyperimmune globulin, 20% received bortezomib and 13% rituximab. Concomitant infection was treated in 40% of patients. The immediate treatment outcome was successful in 91%, the 1‐ and 3‐year graft survival rates were 71% and 57%, while 3‐year patient survival was 97%. Chronic active AMR was associated with worse graft survival than acute AMR (log rank P = 0.06). To conclude, intensive treatment with apheresis and additional immunosuppression was effective in reversing AMR, but long‐term graft survival remains markedly decreased, especially in chronic active AMR.
Subendocardial Viability Ratio Is Impaired in Highly Proteinuric Chronic Kidney Disease Patients With Low Estimated Glomerular Filtration Rate
Authors: Ekart Robert , Šegula Anja , Hartman Tanja , Hojs Nina , Hojs Radovan 
Published: June 2016

AbstractProteinuria and estimated glomerular filtration rate (eGFR) are markers of chronic kidney disease (CKD) and cardiovascular disease. With applanation tonometry, pulse wave analysis and many hemodynamic data are available. One of them is the subendocardial viability ratio (SEVR) which represents a non‐invasive measure of myocardial perfusion related to the work of the heart. The aim of our study was to investigate the importance of SEVR in proteinuric CKD patients and healthy subjects. We performed a cross‐sectional study in a cohort of 90 non‐dialysis CKD patients and 39 healthy controls. SEVR was assessed by radial applanation tonometry (SphygmoCor, Atcor, Australia). Blood samples and urine albumin‐to‐creatinine ratio (UACR) were analyzed. CKD patients were divided in four groups according to the UACR and eGFR: CKD group 1: UACR > 1000 mg/g and eGFR < 30 mL/min; CKD group 2: UACR > 1000 mg/g and eGFR >30 mL/min; CKD group 3: UACR <1000 mg/g and eGFR < 30 mL/min and CKD group 4: UACR < 1000 mg/g and eGFR >30 mL/min. Using one‐way ANOVA, we found a statistically significant difference in SEVR only between CKD group 1 and all other CKD groups and healthy control group (P < 0.022). Results of our study show that only CKD patients with UACR more than 1000 mg/g and eGFR below 30 mL/min have significantly lower SEVR.
Characteristics of the Clostridium difficile cell envelope and its importance in therapeutics
Authors: Kirk Joseph A. , Banerji Oishik , Fagan Robert P. 
Published: June 2016

SummaryClostridium difficile infection (CDI) is a challenging threat to human health. Infections occur after disruption of the normal microbiota, most commonly through the use of antibiotics. Current treatment for CDI largely relies on the broad‐spectrum antibiotics vancomycin and metronidazole that further disrupt the microbiota resulting in frequent recurrence, highlighting the need for C. difficile‐specific antimicrobials. The cell surface of C. difficile represents a promising target for the development of new drugs. C. difficile possesses a highly deacetylated peptidoglycan cell wall containing unique secondary cell wall polymers. Bound to the cell wall is an essential S‐layer, formed of SlpA and decorated with an additional 28 related proteins. In addition to the S‐layer, many other cell surface proteins have been identified, including several with roles in host colonization. This review aims to summarize our current understanding of these different C. difficile cell surface components and their viability as therapeutic targets.
Governing the Global Green Economy
Authors: Tienhaara Kyla 
Published: June 2016

AbstractThe concept of a ‘green economy’ has risen to prominence in recent years. However, little has been said about what actors could drive its widespread adoption at the global level. At present, global governance generally occurs in distinct policy domains or ‘silos’; the global environment and the global economy are segregated. Within these domains, authority is highly fragmented among numerous institutions. However, two particular institutions have the broad scope and potentially the capacity to coordinate and steer green economy efforts: the United Nations Environment Programme (UNEP) and the Group of Twenty (G20). This article examines why some (includingUNEPitself) have called for the G20 to take a greater role in steering the green economy and assesses the extent to which it has done so. The article concludes that the G20 was ineffective in promoting a ‘green recovery’ from the Global Financial Crisis (GFC) and has similarly failed to stimulate ‘green growth’. Reform of both the G20 andUNEPcould improve global policy on the green economy, but changes to the G20 would likely have a greater impact.
Measuring the functional redundancy of biological communities: a quantitative guide
Authors: Ricotta Carlo , de Bello Francesco , Moretti Marco , Caccianiga Marco , Cerabolini Bruno E.L. , Pavoine Sandrine 
Published: June 2016

Summary

The preservation of ecosystem processes under ongoing biotic erosion requires that some species within affected communities perform similar functions, a property that is usually defined as functional redundancy. Although functional redundancy has recently become a relevant part of ecological research, so far there is no agreement on its measurement.

The scope of this work is thus to propose a consistent framework based on functional dissimilarities among species for summarizing different facets of functional redundancy. The behaviour of the proposed measures is illustrated with one small artificial data set, together with actual examples on the species functional turnover along successional gradients.

We believe this new framework provides an important contribution for the clarification and quantification of key metrics of community redundancy and vulnerability. The method, for which we provide a simple r function called ‘uniqueness’, further allows summarizing the functional contribution of single species to the overall redundancy of any type of biological community.