bluuebunny/crossref_metadata_2025_split huggingface dataset:
Broccoli seed extracts but not sulforaphane have strong free radical scavenging activities
Authors: Ligen Zou , Yuanfeng Wu , Yuke Shen , Lei Zhang , Mupunga Jothame , Jianwei Mao , Shiwang Liu 
Published: July 2017

SummaryThe abilities of broccoli seed extracts and purified sulforaphane (SF) to scavenge 2,2′‐azinobis [3‐ethylbenzothiazoline‐6‐sulphonate] (ABTS•+), 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH•) and superoxide anions were studied. The free radical scavenging activities of broccoli seed extracts had no exact correlation with SF content, indicating that SF was not the main antioxidant component. The broccoli seed extracts were separated by high‐speed countercurrent chromatography to obtain purified SF, which showed dose‐dependent free radical scavenging activities in the DPPH• and ABTS•+ assays, but its activities were weaker to those of ascorbic acid. The same trend was observed in the chemiluminescence assay. The results showed that broccoli seed extracts had strong free radical scavenging activities that were not attributable to SF.
Individual‐level Foci of Identification at Work: A Systematic Review of the Literature
Authors: Atewologun Doyin , Kutzer Roxanne , Doldor Elena , Anderson Deirdre , Sealy Ruth 
Published: July 2017

AbstractThis paper presents a systematic literature review of individual‐level targets (or foci) of identification, that is, the bases by which one derives a sense of self as a unique being in the context of work. We reviewed 253 articles from over 30 top management journals between 2005 and 2016. In examining foci types, definitions, underpinning theoretical and philosophical assumptions, we catalogue nine categories of individual‐level identification foci (manager, leader, follower, team, organization, occupation‐specific, professional, career and work), finding a dominance of functionalist meta‐theoretical orientations (comprising over half the sample, with interpretivist approaches comprising about a third of studies). Further, we enhance construct clarity in the field; we identify conceptual challenges with extant definitions of key foci, and offer integrative definitions by specifying scope conditions for each identity focus and semantic relationships between various identity foci. We contextualize our discussion of construct clarity to different research orientations in the field and offer possibilities for theoretical developments therein. Third, we offer an integrative framework for positioning work in the field by scope of interest (identity content or context) and identity construction assumptions (stable or evolving), suggesting directions for future research.
Metatheories and Metaphors of Organizational Identity: Integrating Social Constructionist, Social Identity, and Social Actor Perspectives within a Social Interactionist Model
Authors: Haslam S. Alexander , Cornelissen Joep P. , Werner Mirjam D. 
Published: July 2017

AbstractThis review examines three dominant metatheories of organizational identity that are grounded in social constructionist, social identity, and social actor theorizing. It focuses on root metaphors of framing, categorization and personification that are associated with each metatheory and outlines differences in their assumptions, key constructs, and forms of analysis. The review shows how the emphasis of each root metaphor serves to direct research along a particular path in ways that often lead to a siloing of research knowledge. However, while laying bare the foundations of each metatheory and discussing the nature of the empirical projects by which they are supported, we also seek to draw them more closely together. In particular, we do this by elaborating an integrative social interactionist model in which organizational identity is understood to be the product of recursive interaction between bottom‐up and top‐down processes of identity consensualization and contestation.
Intraoperative indocyanine green fluorescent angiography‐assisted modified superior gluteal artery perforator flap for reconstruction of sacral pressure sores
Authors: Chang Chun‐Kai , Wu Chien‐Ju , Chen Chun‐Yu , Wang Chi‐Yu , Chu Tzi‐Shiang , Hsu Kuo‐Feng , Chiu Han‐Ting , Liu Hung‐Hui , Chou Chang‐Yi , Wang Chih‐Hsin , Lin Chin‐Ta , Dai Niann‐Tzyy , Tzeng Yuan‐Sheng 
Published: July 2017

ABSTRACTPressure sores are often observed in patients who are bedridden. They can be a severe problem not only for patients and their caregivers but also for plastic surgeons. Here, we describe a new method of superior gluteal artery perforator flap harvesting and anchoring with the assistance of intraoperative indocyanine green fluorescent angiography. In this report, we describe the procedure and outcomes for 19 patients with grades III and IV sacral pressure sores who underwent the operation between September 2015 and November 2016. All flaps survived, and two experienced wound‐edge partial dehiscence. With the assistance of this imaging device, we were able to acquire a reliable superior gluteal artery perforator flap and perform modified operations with it that are safe, easy to learn and associated with fewer complications than are traditional.
Independent association between age and circadian systolic blood pressure patterns in adults with hypertension
Authors: Deng Ming , Chen Da‐Wei , Dong Yi‐Fei , Lu Peng , Zhan Bi‐Ming , Xu Jian‐Qing , Ji Xi‐Xin , Li Ping , Cheng Xiao‐Shu 
Published: July 2017

Previous studies indicate a preliminary association between age and circadian blood pressure (BP) variation. This association would be affected by confounding factors in real‐world populations. The authors investigated whether this is a convincingly independent association in a real‐world population of adults with hypertension. Clinical data and findings of 24‐hour ambulatory BP monitoring were obtained from 297 consecutive adults with hypertension (60.19±0.77 years). BP dipping patterns were categorized based on the percentage of nocturnal BP drop. Multivariate linear regression analysis identified an independent correlation between age and percentage of nocturnal systolic BPdrop (β=−7.296; 95% CI, −10.430 to −4.162 [P<.001]). Reverse dippers were the oldest and extreme dippers were the youngest. A significant age difference was noted among patients grouped into four BP dipping patterns with and without adjustments for sex, body mass index, drugs, diabetes mellitus, smoking, 24‐hour mean heart rate, and 24‐hour mean systolic and diastolic BP.
Tai Chi for Risk of Falls. A Meta‐analysis
Authors: Lomas‐Vega Rafael , Obrero‐Gaitán Esteban , Molina‐Ortega Francisco J. , Del‐Pino‐Casado Rafael 
Published: July 2017

ObjectivesTo analyze the effectiveness of tai chi for falls prevention.DesignSystematic review and meta‐analysis.SettingPubmed, Scopus, CINHAL, and Physiotherapy Evidence Database (PEDro) were searched to May 26, 2016.ParticipantsOlder adult population and at‐risk adults.InterventionRandomized controlled trials analyzing the effect of tai chi versus other treatments on risk of falls.MeasurementsThe incidence rate ratio (IRR) for falls incidence and hazard ratio (HR) for time to first fall.ResultsThe search strategy identified 891 potentially eligible studies, of which 10 met the inclusion criteria. There was high‐quality evidence of a medium protective effect for fall incidence over the short term (IRR = 0.57; 95% CI = 0.46, 0.70) and a small protective effect over the long term (IRR = 0.87; 95% CI = 0.77, 0.98). Regarding injurious falls, we found very low‐quality evidence of a medium protective effect over the short term (IRR = 0.50; 95% CI = 0.33, 0.74) and a small effect over the long term (IRR = 0.72; 95% CI = 0.54, 0.95). There was no effect on time to first fall, with moderate quality of evidence (HR = 0.98; 95% CI = 0.69, 1.37).ConclusionIn at‐risk adults and older adults, tai chi practice may reduce the rate of falls and injury‐related falls over the short term (<12 months) by approximately 43% and 50%, respectively. Tai chi practice may not influence time to first fall in these populations. Due to the low quality of evidence, more studies investigating the effects of tai chi on injurious falls and time to first fall are required.
Long‐term use of dienogest in the treatment of painful symptoms in adenomyosis
Authors: Osuga Yutaka , Watanabe Manabu , Hagino Atsushi 
Published: July 2017

AbstractAimWe aimed to investigate the safety and efficacy of dienogest (DNG), a progestational 19‐norsteroid, administered for 52 weeks in patients with symptomatic adenomyosis.MethodsA total of 130 patients with adenomyosis received 2 mg of DNG orally each day for 52 weeks. In cases of complicated anemia, patients were treated for anemia prior to receiving the medication. Adverse events and adverse drug reactions were evaluated. The patients' pain symptoms (dysmenorrhea and pelvic pain from adenomyosis) were assessed using a pain‐scoring tool. This was a verbal rating scale comprising a 0–3‐point pain‐severity score measuring disability to work, and an analgesics‐usage score measuring need for analgesics.ResultsThe most common adverse drug reactions included metrorrhagia (96.9%) and hot flush (7.7%). However, in most cases, metrorrhagia was tolerable and no clinically significant changes were observed concerning the incidence or severity of reactions during the 52‐week treatment period. There were no serious adverse events. Both the pain‐severity score and analgesics‐usage score decreased after the start of treatment with DNG. The mean ± standard deviation changes from baseline for the pain score were −3.4 ± 1.8 at 24 weeks and −3.8 ± 1.5 at 52 weeks, respectively.ConclusionThe long‐term use of DNG was well‐tolerated and effective in patients with symptomatic adenomyosis.
Global Cities, Connectivity, and the Location Choice of MNC Regional Headquarters
Authors: Belderbos René , Du Helen S. , Goerzen Anthony 
Published: July 2017

AbstractRegional headquarters (RHQs) perform a crucial bridging function between corporate headquarters, regional affiliates, and other regional actors. Their bridging role and associated connectivity needs lead MNCs to locate their RHQs in highly connected ‘global cities’. We examine how the interplay between global city connectivity, geographic distance, and RHQ roles determine the likelihood that particular cities are chosen as a location for MNCs’ RHQ investments. Our inferences are based on an analysis of location choices for 1031 RHQs among 48 global cities. We find that while the geographic distance of a global city to the MNC's regional affiliates diminishes the likelihood that a given city is chosen, these distance effects disappear when the global city is highly connected. Well connected global cities, furthermore, attract investment in RHQs by MNCs from more distant countries‐of‐origin. On average, city connectivity is a more important characteristic for RHQs that have an entrepreneurial role.
A widespread cyanobacterium supported by polyphasic approach: proposition of Koinonema pervagatum gen. & sp. nov. (Oscillatoriales)1
Authors: Buch Bruna , Martins Mariéllen Dornelles , Branco Luis Henrique Z. 
Published: July 2017

Several new genera originally classified as the genus Phormidium, a polyphyletic and taxonomically complex genus within the Oscillatoriales, were recently described. The simple morphology of Phormidium does not reflect its genetic diversity and the delimitation of a natural group is not possible with traditional classification systems based on morphology alone. Therefore, this study used morphological, ecological, and molecular approaches to evaluate four populations morphologically similar to Ammassolinea, Kamptonema, and Ancylothrix (simple, curved, and gradually attenuated at the ends trichome), found in subtropical and tropical Brazilian regions. 16S rRNA gene sequences grouped all the strains in a highly supported clade with other two European strains isolated from thermal springs surrounding areas. The 16S‐23S ITS secondary structure corroborated the phylogenetic analysis with all the strains having similar structures. Consequently, a genetically well‐defined and cryptic new genus, Koinonema gen. nov., is proposed containing the aquatic, mesophilic, and morphologically homogeneous new species, Koinonema pervagatum sp. nov.
Appearance and characterization of fruit image textures for quality sorting using wavelet transform and genetic algorithms
Authors: Khoje Suchitra 
Published: July 2017

AbstractImages of four qualities of mangoes and guavas are evaluated for color and textural features to characterize and classify them, and to model the fruit appearance grading. The paper discusses three approaches to identify most discriminating texture features of both the fruits. In the first approach, fruit's color and texture features are selected using Mahalanobis distance. A total of 20 color features and 40 textural features are extracted for analysis. Using Mahalanobis distance and feature intercorrelation analyses, one best color feature (mean ofa* [L*a*b* color space]) and two textural features (energya*, contrast of H*) are selected as features for Guava while two best color features (R std, H std) and one textural features (energyb*) are selected as features for mangoes with the highest discriminate power. The second approach studies some common wavelet families for searching the best classification model for fruit quality grading. The wavelet features extracted from five basic mother wavelets (db, bior, rbior, Coif, Sym) are explored to characterize fruits texture appearance. In third approach, genetic algorithm is used to select only those color and wavelet texture features that are relevant to the separation of the class, from a large universe of features. The study shows that image color and texture features which were identified using a genetic algorithm can distinguish between various qualities classes of fruits. The experimental results showed that support vector machine classifier is elected for Guava grading with an accuracy of 97.61% and artificial neural network is elected from Mango grading with an accuracy of 95.65%.Practical applicationsThe proposed method is nondestructive fruit quality assessment method. The experimental results has proven that Genetic algorithm along with wavelet textures feature has potential to discriminate fruit quality. Finally, it can be concluded that discussed method is an accurate, reliable, and objective tool to determine fruit quality namely Mango and Guava, and might be applicable to in‐line sorting systems
Pharmacokinetic–pharmacodynamic integration and modelling of oxytetracycline for the calf pathogensMannheimia haemolyticaandPasteurella multocida
Authors: Lees P. , Potter T. , Pelligand L. , Toutain P.‐L. 
Published: July 2017

A calf tissue cage model was used to study the pharmacokinetics (PK) and pharmacodynamics (PD) of oxytetracycline in serum, inflamed (exudate) and noninflamed (transudate) tissue cage fluids. After intramuscular administration, the PK was characterized by a long mean residence time of 28.3 hr. Based on minimum inhibitory concentrations (MICs) for six isolates each ofMannheimia haemolyticaandPasteurella multocida, measured in serum, integration of in vivo PK and in vitro PD data established area under serum concentration–time curve (AUC0–∞)/MIC ratios of 30.0 and 24.3 hr forM. haemolyticaandP. multocida, respectively. Corresponding AUC0–∞/MIC ratios based on MICs in broth were 656 and 745 hr, respectively. PK‐PD modelling of in vitro bacterial time–kill curves for oxytetracycline in serum established mean AUC0–24 hr/MIC ratios for 3log10decrease in bacterial count of 27.5 hr (M. haemolytica) and 60.9 hr (P. multocida). Monte Carlo simulations predicted target attainment rate (TAR) dosages. Based on the potency of oxytetracycline in serum, the predicted 50% TAR single doses required to achieve a bacteriostatic action covering 48‐hr periods were 197 mg/kg (M. haemolytica) and 314 mg/kg (P. multocida), respectively, against susceptible populations. Dosages based on the potency of oxytetracycline in broth were 25‐ and 27‐fold lower (7.8 and 11.5 mg/kg) forM. haemolyticaandP. multocida,respectively.
Central nervous system infection due to Cryptococcus gattii sensu lato in India: Analysis of clinical features, molecular profile and antifungal susceptibility
Authors: Lahiri Mukhopadhyay Shayanki , Bahubali Veenakumari H. , Manjunath Netravathi , Swaminathan Aarthi , Maji Sayani , Palaniappan Marimuthu , Parthasarathy Satishchandra , Chandrashekar Nagarathna 
Published: July 2017

SummaryCryptococcus gattii species complex has evolved as a pathogen in the last two decades causing infection among both immunocompetent and immunocompromised hosts. We aimed to analyse the clinical features of CNS infection caused by C. gattii sensu lato, molecular and antifungal susceptibility profile of this pathogen. Cases diagnosed to have CNS cryptococcosis were included in the study. Cryptococcus recovered from patient's specimen was identified by standard protocol. Species confirmation, mating type and molecular type determination were performed by PCR based methods. Antifungal susceptibility was tested in VITEK2C to amphotericin B, 5‐flucytosine, fluconazole and voriconazole. Among 199 cases, 20 (10%) were due to C. gattii, comprising of 75% cryptococcal meningitis and 25% cryptococcoma cases. Young adult males were commonly affected. Headache and vomiting were prominent symptoms and 50% were immunocompromised. Among the isolates, 75%, 20% and 5% were C. tetragattii, C. gattii sensu stricto and C. bacillisporus respectively and all had mating type α. Four (20%) isolates of C. tetragattii and the only isolate of C. bacillisporus were resistant to fluconazole. The most common species isolated from south India is C. tetragattii. The study contributes to the epidemiology of C. gattii and reiterates the need for genotyping and antifungal susceptibility testing.
Longitudinal dental maturation of children with complete unilateral cleft lip and palate: A case‐control cohort study
Authors: Tan E. L. Y. , Kuek M. C. , Wong H. C. , Yow M. 
Published: July 2017

Structured AbstractObjectivesMany reports suggest that children with cleft lip and palate (CLP) have delayed dental development and asymmetrical timing of tooth‐pair formation. We aimed to investigate the dental maturation of permanent teeth in children with complete unilateral CLP (UCLP) and compare the findings with non‐CLP children.Setting and sample populationThis case‐control study used 115 radiographs of children with complete UCLP and controls (non‐CLP children matched on age, gender and ethnicity) from a hospital‐based dental clinic in Singapore.Material and methodsOrthopantomographs of 60 children with complete UCLP (5‐9 years old) and 55 children (9‐13 years old) from the same cohort were investigated using the Demirjian's method and compared with controls to determine if there were any differences in dental maturation with age.ResultsDelayed dental maturation was found in the 5‐ to 9‐year‐old children with UCLP compared to controls by 0.55 years (standard deviation: 0.75) (P<.001). There was no significant difference between the dental maturation of children with UCLP and controls in the 9‐ to 13‐year‐old group (P=.744). The group with UCLP had higher risk of asymmetrically developing tooth pairs than the control group for both age groups (P<.001).ConclusionNo difference in dental maturation between UCLP and controls in the 9‐ to 13‐year‐old group was found. However, there was diametrical difference in dental maturation in the 5‐ to 9‐year‐old group, which attenuated as they grew older. There was a consistently higher risk of asymmetrical tooth formation in children with UCLP than in controls.
Concordance between self‐reported and observer‐rated anxiety severity in outpatients with anxiety disorders: The Leiden routine outcome monitoring study
Authors: Schat Anke , van Noorden Martijn S. , Giltay Erik J. , Noom Marc J. , Vermeiren Robert R.J.M. , Zitman Frans G. 
Published: July 2017

ObjectivesAnxiety severity measures can be self‐report or observer‐rated. Although mostly these measures concur, they can diverge markedly. We examined concordance between two anxiety scales: the observer‐rated Brief Anxiety Scale (BAS) and the self‐report Brief Symptom Inventory 12‐item version (BSI‐12), and described associations between patient characteristics and discordance.DesignThe study used an observational design, using prospective data from 2,007 outpatients with DSM‐IV‐TR panic disorder with or without agoraphobia, agoraphobia without panic, social phobia, and/or generalized anxiety disorder.MethodsOverall agreement was described using Pearson's product–moment correlation coefficient. Associations between patient characteristics and discordance (defined as |Z‐BAS‐Z‐BSI‐12| ≥ 1) were evaluated with univariable and multivariable multinomial logistic regression analyses.ResultsOverall correlation between BAS and BSI‐12 was positive and strong (r = .59). Discordance occurred in 24.8% of patients ([Z‐BAS ≥ Z‐BSI‐12 + 1] = 12.2%; [Z‐BAS ≤ Z‐BSI‐12 − 1] = 12.6%). Patients with higher observed than self‐reported anxiety severity did not differ from concordant patients. Patients with lower observed than self‐reported anxiety severity more often had panic disorder, less often had social phobia, and had higher scores on cluster B and C personality characteristics than concordant patients. Lower observed than self‐reported anxiety severity was best predicted by panic disorder, social phobia, and affective lability.ConclusionsResults demonstrate that the use of a single source of information gives a one‐sided view of pathology. A multimethod approach is highly preferable, as this allows for assessment across different domains and through multiple sources of information, and as such, provides clinicians with vital information.Practitioner points

When assessing anxiety severity, the use of self‐report measures provides additional information to observer‐rated measures.

In patients who have strong cluster B and C personality traits, anxiety severity might be overlooked, even by trained observers.

The use of a multimethod assessment strategy is preferable in anxiety severity assessment.
Systems and techniques used in the culture of soft‐shell swimming crabs
Authors: Tavares Camila Prestes dos Santos , Silva Ubiratã Assis Teixeira , Pereira Leandro Angelo , Ostrensky Antonio 
Published: July 2017

AbstractThe academic interest in the production of soft‐shell swimming crabs has increased in direct proportion to the increasing demand worldwide for this gastronomic delicacy. The techniques of obtaining this product are essentially based on the maintenance of swimming crabs at premoult stage in open, semi‐closed or closed farming systems, until the moment of moulting. These different types of systems reflect the biological e environmental control method evolution. To achieve industrial scale production of soft swimming crabs, the option of using closed systems has increased in recent years. This type of system offers several advantages, such as greater control over environmental variables, greater ease of installation, higher storage densities, greater ease of monitoring ecdysis occurrence and, especially, the possibility of incorporating several forms of automation. In this review, the main production systems currently used, as well as the main techniques for obtaining the animals, their management under controlled conditions, harvesting and slaughter, are presented and discussed, focusing on future perspectives for the world production of soft‐shell swimming crabs.