bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of 10-year SAO OMI ozone profile (PROFOZ) product using Aura MLS measurements
Authors: Huang Guanyu , Liu Xiong , Chance Kelly , Yang Kai , Cai Zhaonan 
Published: January 2018

Abstract. We validate the Ozone Monitoring Instrument (OMI) ozone
profile (PROFOZ v0.9.3) product including ozone profiles between
0.22 and 261 hPa and stratospheric ozone columns (SOCs) down to 100, 215, and
261 hPa from October 2004 through December 2014 retrieved by the Smithsonian
Astrophysical Observatory (SAO) algorithm against the latest Microwave Limb
Sound (MLS) v4.2x data. We also evaluate the effects of OMI row anomaly (RA)
on the retrieval by dividing the data set into before and after the
occurrence of serious RA, i.e., pre-RA (2004–2008) and post-RA (2009–2014).
During the pre-RA period, OMI ozone profiles agree very well with MLS data.
After applying OMI averaging kernels to MLS data, the global mean biases (MBs) are within 3 % between 0.22 and 100 hPa,
negative biases are within 3–9 % for lower layers, and the standard deviations (SDs) are
3.5–5 % from 1 to 40 hPa, 6–10 % for upper layers, and 5–20 %
for lower layers.
OMI shows biases dependent on latitude and solar zenith angle (SZA), but MBs and SDs are
mostly within 10 % except for low and high altitudes of high latitudes and SZAs.
Compared to the retrievals during the pre-RA period, OMI retrievals during
the post-RA period degrade slightly between 5 and 261 hPa with MBs and SDs
typically larger by 2–5 %, and degrade much more for pressure less than ∼ 5 hPa, with larger MBs by up
to 8 % and SDs by up to 15 %,
where the MBs are larger by 10–15 % south of 40∘ N due to the
blockage effect of RA and smaller by 15–20 % north of 40∘ N due
to the solar contamination effect of RA. The much worse comparisons at high
altitudes indicate the UV1 channel of pixels that are not flagged as RA is
still affected by the RA. During the pre-RA period, OMI SOCs show very good
agreement with MLS data with global mean MBs within 0.6 % and SDs of
1.9 % for SOCs down to 215 and 261 hPa and of 2.30 % for SOC down to
100 hPa. Despite clearly worse ozone profile comparisons during the post-RA
period, OMI SOCs only slightly degrade, with SDs larger by 0.4–0.6 %
mostly due to looser spatial coincidence criteria as a result of missing
data from RA and MBs larger by 0.4–0.7 %. Our retrieval comparisons
indicate significant bias trends, especially during the post-RA period. The
spatiotemporal variation of our retrieval performance suggests the need to
improve OMI's radiometric calibration to maintain the long-term stability and
spatial consistency of the PROFOZ product.
Mechanism of groundwater inrush hazard caused by solution mining in a multilayered rock-salt-mining area: a case study in Tongbai, China
Authors: Zeng Bin , Shi Tingting , Chen Zhihua , Xiang Liu , Xiang Shaopeng , Yang Muyi 
Published: January 2018

Abstract. The solution mining of salt mineral resources may contaminate
groundwater and lead to water inrush out of the ground due to brine leakage.
Through the example of a serious groundwater inrush hazard in a large salt-mining area in Tongbai County, China, this study mainly aims to analyse the
source and channel of the inrushing water. The mining area has three
different types of ore beds including trona (trisodium hydrogendicarbonate
dihydrate, also sodium sesquicarbonate dihydrate, with the formula
Na2CO3 × NaHCO3 × 2H2O, it is a
non-marine evaporite mineral), glauber (sodium sulfate, it is the inorganic
compound with the formula Na2SO4 as well as several
related hydrates) and gypsum (a soft sulfate mineral composed of calcium
sulfate dihydrate, with chemical formula CaSO4 × 2H2O).
Based on characterisation of the geological and hydrogeological conditions,
the hydrochemical data of the groundwater at different points and depths were
used to analyse the pollution source and the pollutant component from single
or mixed brine by using physical–chemical reaction principle analysis and
hydrogeochemical simulation method. Finally, a possible brine leakage
connecting the channel to the ground was discussed from both the geological and
artificial perspectives. The results reveal that the brine from the trona mine is
the major pollution source; there is a NW–SE fissure zone controlled by the
geological structure that provides the main channels through which brine can
flow into the aquifer around the water inrush regions, with a large number
of waste gypsum exploration boreholes channelling the
polluted groundwater inrush out of the ground. This research can be a
valuable reference for avoiding and assessing groundwater inrush hazards in
similar rock-salt-mining areas, which is advantageous for both groundwater
quality protection and public health.
Towards a monitoring system of temperature extremes in Europe
Authors: Lavaysse Christophe , Cammalleri Carmelo , Dosio Alessandro , van der Schrier Gerard , Toreti Andrea , Vogt Jürgen 
Published: January 2018

Abstract. Extreme-temperature anomalies such as heat and cold waves may have strong impacts on human activities and health. The heat waves in western Europe in 2003 and in Russia in 2010, or the cold wave in southeastern Europe in 2012, generated a considerable amount of economic loss and resulted in the death of several thousands of people. Providing an operational system to monitor extreme-temperature anomalies in Europe is thus of prime importance to help decision makers and emergency services to be responsive to an unfolding extreme event. In this study, the development and the validation of a monitoring system of extreme-temperature anomalies are presented. The first part of the study describes the methodology based on the persistence of events exceeding a percentile threshold. The method is applied to three different observational datasets, in order to assess the robustness and highlight uncertainties in the observations. The climatology of extreme events from the last 21 years is then analysed to highlight the spatial and temporal variability of the hazard, and discrepancies amongst the observational datasets are discussed. In the last part of the study, the products derived from this study are presented and discussed with respect to previous studies. The results highlight the accuracy of the developed index and the statistical robustness of the distribution used to calculate the return periods.
(Des)colonialidad del poder en 13 pueblos en defensa del agua, el aire y la tierra
Authors: Velazco Salvador 
Published: January 2018

En este artículo se analiza el documental de Francesco Taboada, 13 pueblos en defensa del agua, el aire y la tierra (2008), desde la perspectiva de la “colonialidad del poder”, entendiendo este concepto, de acuerdo con Walter Mignolo, como la subordinación del conocimiento y la cultura de grupos subalternos y excluidos que viene aparejada con la modernidad occidental. Taboada pone de relieve el papel jugado por el movimiento de los 13 pueblos del Estado de Morelos en una lucha que podríamos señalar como épica por la defensa no sólo de los recursos naturales (agua, tierras y bosques) sino de los derechos plenos de las comunidades indígenas. Esta obra es un referente obligado para documentar los movimientos de los pueblos y las luchas sociales que se están librando en el México neoliberal de nuestros días.
Las “perspectivas caleidoscópicas” en los videos musicales Afterlife y Porno: from the Reflektor Tapes de Arcade Fire
Authors: Ledezma G. María Isabel 
Published: January 2018

Este artículo desarrolla la noción de “perspectiva caleidoscópica” en dos videos musicales pertenecientes a la banda canadiense Arcade Fire titulados Afterlife y Porno: from the Reflektor Tapes. Estos trabajos audiovisuales exponen tres tópicos fundamentales: el mito de Orfeo y Eurídice, el componente negro o “la negritud”, característico de Brasil y Haití, y los procesos ritualísticos asociados a las comunidades afrocaribeñas como el vudú o la santería candomblé. La manera como estos tópicos son insertados en la narrativa de los videos musicales permite suponer que existe, en estos, un juego constante de apropiaciones y distanciamientos, en simultaneidad, los cuales asemejan a la dinámica de los caleidoscopios, y que son usados en los videos con fines estéticos. El producto final del uso de estas dinámicas es la presentación de dos videos musicales que trascienden su función de productos promocionales y de marketing para convertirse en trabajos artísticos que reivindican las prácticas identitarias de la comunidad afrocaribeña. Palabras claves: medios audiovisuales, identidad cultural, Caribe, Brasil
Fighting over the Dead: John Wesley, Ritualism, and the Politics of Church and State in 1870s England
Authors: Danker Ryan Nicholas 
Published: January 2018

ABSTRACT
John Wesley was to play a surprisingly contemporary role in the political debates of Victorian England. Nonconformist Methodists and High Church Anglicans battled for ‘rights’ to the evangelical leader. Presenting their differing ‘Wesleys’ to the world, the authors of books and pamphlets painted Wesley as one of their own within a contentious political environment with high stakes for the establishment of Church and State. That Wesley would have found Victorian politics foreign was not the authors' concern. The episode discussed here represents one in the long journey to grasp the multifaceted and elusive Wesley and to define Methodism.
Low-pressure monopolar electroresection of the prostate for glands sized > 70 vs. < 70 cc performed with continuous irrigation and suprapubic suction: perioperative and long-term outcome
Authors: Wilhelm Konrad , Cazana Ioana Maria , Schoenthaler Martin , Katzenwadel Arndt , Spaeth Johannes , Miernik Arkadiusz 
Published: January 2018

Abstract
Purpose
To evaluate long-term efficacy and safety of low-pressure transurethral resection of the prostate for prostates < 70 cc (group 1) vs. > 70 cc (group 2).

Patients and methods
In this study patients operated with monopolar TURP between 2009 and 2012 were evaluated retrospectively. During surgery a specially designed trocar (18 Fr) was placed suprapubically and connected to a suction pump to maintain stable low-pressure conditions. After sample size calculations, long-term follow-up was completed for 70 invited patients in each group up to 9/2015.

Results
Follow-up period was 57 vs. 56 months for group 1 and 2, respectively (p = 0.56). At baseline there was no significant difference in age, IPSS, peak flow, and post void residual (PVR). Mean prostate volume was 47 cc (15–65) vs. 100 cc (70–163). Mean operating time was 55.4 vs. 82.6 min (p = 0.00). Blood transfusion was necessary in 0.0 vs. 2.9% (p = 0.16), and 0.0 vs. 1.4% developed TUR syndrome (p = 0.32). At follow-up mean relative improvement in IPSS was 63 vs. 57% (p = 0.29), QoL 64 vs. 64% (p = 0.93), peak flow 139 vs. 130% (p = 0.85), and PVR 58 vs. 63% (p = 0.80). Long-term complications included recurring adenoma in 1.4 vs. 4.3% (p = 0.31), and stricture in 7.2 vs. 5.8% (p = 0.73). 1 patient in each group reported worsening incontinence symptoms.

Conclusions
In terms of safety and efficacy, the aforementioned modality of standardized monopolar TURP using suprapubic suction was non-inferior for prostates > 70 cc compared to the same procedure for prostates < 70 cc. This technique is a potential low-cost alternative for clinics that cannot afford modern laser approaches.

Study register number
DRKS00006527.
Fratura proximal do fêmur e lesão vascular em adultos – Relato de caso
Authors: Labronici Pedro José , Santos Filho Fernando Claudino dos , Diamantino Yuri Leander Oliveira , Loureiro Eduardo , Ezequiel Maria Cristina Diniz Gonçalves , Alves Sérgio Delmonte 
Published: January 2018

ResumoComplicações vasculares no tratamento cirúrgico da fratura do quadril são raras. A depender da lesão arterial, pode ocorrer um grave sangramento intraoperatório ou formação de hematoma subagudo com desenvolvimento de pseudoaneurisma arterial. Na literatura, as complicações mais frequentes relatadas são a formação de grandes hematomas locais após osteossíntese com parafuso deslizante do quadril. O objetivo do presente relato foi demonstrar um caso de lesão arterial tardia após osteossíntese proximal do fêmur.
Beyond Form and Fancy: The Merchant Palaces of Kazimierz Dolny in Poland
Authors: Jakobiec Katie 
Published: January 2018

AbstractThis article builds upon Jan Białostocki's seminal bookThe Art of the Renaissance in Eastern Europeby examining two merchant palaces in the port city of Kazimierz Dolny on the Vistula River in Poland but departs from his interpretation of them. Focusing on the stucco architecture and relief-sculpture of their façades, the article argues against Białostocki's traditional reading of imitation as being driven by artistic influence, and, through the study of the city's mercantile and pilgrimage context, it proposes instead that a notion of imitation that was deeply immersed in sophisticated practices of copying and reference making. It concludes that the merchant community in Kazimierz Dolny was aiming to forge a new civic identity in order to contend in a broader social, religious and economic realm that was traversed by merchants, travellers and pilgrims alike.
‘Let us Sin with Salvin’: Architecture and Authority at the Tower of London, 1896–1905
Authors: Inglesby Roisin 
Published: January 2018

AbstractThe Tower of London is one of the most famous sites in the world, yet its recent architectural history has been almost entirely overlooked. This article represents the first attempt to explore the architectural approach taken by the Tower authorities at the turn of the twentieth century. It analyses the on-going programme of restoration undertaken by the Office of Works during this period in the context of the Tower's singular status as military garrison, historic monument and preeminent tourist attraction, and it considers the Office's stance in relation to increasing public and parliamentary interest in the preservation and restoration of historic buildings. Historic Royal Palaces' collection of architectural drawings offers an unexplored insight into the activities of the Office of Works during this time. Through a close reading of these drawings I show that, contrary to what has previously been supposed, the Office's interventions continued well past the radical restorations of the 1880s and into the twentieth century, as they sought to control the historical narrative of the site through its architecture.
Belastbare und effiziente Wissenschaft
Authors: Glöckner Andreas , Fiedler Susann , Renkewitz Frank 
Published: January 2018

Zusammenfassung. Die Replikationskrise innerhalb der Psychologie hat eine Diskussion über gängige Praktiken im Forschungsprozess und die beteiligten Institutionen ausgelöst. Wir stellen Maßnahmen vor, die dazu beitragen können, Forschung effizienter und Forschungsergebnisse belastbarer zu machen, indem sie eine strategische Ausrichtung und stärkere Verzahnung von Forschungsprozessen in Gang setzen. Die notwendigen Veränderungen setzen dabei auf der Ebene des Individuums sowie der Institutionen an und betreffen die Inhaltsbereiche Theorie, Empirie und Evidenzakkumulation. Über die bekannten eher spezifischen Maßnahmen zur Verbesserung der Reproduzierbarkeit hinaus, zielen unsere Vorschläge darauf ab, die Voraussetzungen für effizientes wissenschaftliches Arbeiten zu verbessern, indem u. a. (i) die exakte Spezifikation und die kritische Testung und Revision von Theorien wieder stärker in den Mittelpunkt der Forschung gerückt werden, (ii) eine Kultur der Transparenz, akzeptierten Fehlbarkeit und Offenheit für Empirie- aber insbesondere auch Theorierevision etabliert wird, (iii) diese Kultur und die damit verbundene Methodik als integrale Bestandteile durchgängig in der Lehre verankert werden und (iv) Evidenz und Theorien in fortlaufend dezentral aktualisierten und miteinander verknüpften Theorie- und Empirie-Datenbanken zusammengeführt werden.
Cerling and Ehleringer Receive 2017 Excellence in Earth and Space Science Education Award
Authors:   AGU
Published: January 2018

Thure Cerling and James Ehleringer received the 2017 Excellence in Earth and Space Science Education Award at the American Geophysical Union Fall Meeting Honors Ceremony, held on 13 December 2017 in New Orleans, La. The award honors “a sustained commitment to excellence in geophysical education by a team, individual, or group.”
The epigenetically regulated miR-494 associates with stem-cell phenotype and induces sorafenib resistance in hepatocellular carcinoma
Authors: Pollutri Daniela , Patrizi Clarissa , Marinelli Sara , Giovannini Catia , Trombetta Elena , Giannone Ferdinando A. , Baldassarre Maurizio , Quarta Santina , Vandewynckel Y. P. , Vandierendonck A. , Van Vlierberghe H. , Porretti Laura , Negrini Massimo , Bolondi Luigi , Gramantieri Laura , Fornari Francesca 
Published: January 2018

AbstractHepatocellular carcinoma (HCC) represents the second cause of cancer-related mortality worldwide and is associated with poor prognosis, especially in patients not amenable for curative treatments. The multi-kinase inhibitor sorafenib represents the first-line treatment option for advanced HCC; nevertheless, its effectiveness is limited due to tumor heterogeneity as well as innate or acquired drug resistance, raising the need for new therapeutic strategies. MicroRNAs (miRNAs) involvement in treatment response as well as their safety and efficacy in preclinical models and clinical trials have been widely documented in the oncologic field, including HCC. Here, we identified miR-494 upregulation in a subgroup of human and rat HCCs with stem cell-like characteristics, as well as multiple epigenetic mechanisms involved in its aberrant expression in HCC cell lines and patients. Moreover, we identified p27, puma and pten among miR-494 targets, contributing to speed up cell cycle progression, enhance survival potential in stressful conditions and increase invasive and clonogenic capabilities. MiR-494 overexpression increased sorafenib resistance via mTOR pathway activation in HCC cell lines and, in line, high miR-494 levels associated with decreased sorafenib response in two HCC animal models. A sorafenib-combined anti-miR-494-based strategy revealed an enhanced anti-tumor potential with respect to sorafenib-only treatment in our HCC rat model. In conclusion, our findings suggested miR-494 as a possible therapeutic target as well as a candidate biomarker for patient stratification in advanced HCC.
Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria
Authors: Samanta Krishna , Mirams Gary R. , Parekh Anant B. 
Published: January 2018

AbstractMitochondrial Ca2+ homoeostasis regulates aerobic metabolism and cell survival. Ca2+ flux into mitochondria is mediated by the mitochondrial calcium uniporter (MCU) channel whereas Ca2+ export is often through an electrogenic Na+–Ca2+ exchanger. Here, we report remarkable functional versatility in mitochondrial Na+–Ca2+ exchange under conditions where mitochondria are depolarised. Following physiological stimulation of cell-surface receptors, mitochondrial Na+–Ca2+ exchange initially operates in reverse mode, transporting cytosolic Ca2+ into the matrix. As matrix Ca2+ rises, the exchanger reverts to its forward mode state, extruding Ca2+. Transitions between reverse and forward modes generate repetitive oscillations in matrix Ca2+. We further show that reverse mode Na+–Ca2+ activity is regulated by the mitochondrial fusion protein mitofusin 2. Our results demonstrate that reversible switching between transport modes of an ion exchanger molecule generates functionally relevant oscillations in the levels of the universal Ca2+ messenger within an organelle.
CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts
Authors: Tabet Ricardos , Schaeffer Laure , Freyermuth Fernande , Jambeau Melanie , Workman Michael , Lee Chao-Zong , Lin Chun-Chia , Jiang Jie , Jansen-West Karen , Abou-Hamdan Hussein , Désaubry Laurent , Gendron Tania , Petrucelli Leonard , Martin Franck , Lagier-Tourenne Clotilde 
Published: January 2018

AbstractExpansion of G4C2 repeats in the C9ORF72 gene is the most prevalent inherited form of amyotrophic lateral sclerosis and frontotemporal dementia. Expanded transcripts undergo repeat-associated non-AUG (RAN) translation producing dipeptide repeat proteins from all reading frames. We determined cis-factors and trans-factors influencing translation of the human C9ORF72 transcripts. G4C2 translation operates through a 5′–3′ cap-dependent scanning mechanism, requiring a CUG codon located upstream of the repeats and an initiator Met-tRNAMeti. Production of poly-GA, poly-GP, and poly-GR proteins from the three frames is influenced by mutation of the same CUG start codon supporting a frameshifting mechanism. RAN translation is also regulated by an upstream open reading frame (uORF) present in mis-spliced C9ORF72 transcripts. Inhibitors of the pre-initiation ribosomal complex and RNA antisense oligonucleotides selectively targeting the 5′-flanking G4C2 sequence block ribosomal scanning and prevent translation. Finally, we identified an unexpected affinity of expanded transcripts for the ribosomal subunits independently from translation.
Comparison of Adaptation between the Major Connectors Fabricated from Intraoral Digital Impressions and Extraoral Digital Impressions
Authors: Gan Ning , Ruan Yaye , Sun Jian , Xiong Yaoyang , Jiao Ting 
Published: January 2018

AbstractThe objective was to compare the adaptation between the major connectors of removable partial dentures derived from intraoral digital impressions and extraoral digital impressions. Twenty-four volunteers were enrolled. Each volunteer received an intraoral digital impression and one extraoral digital impression digitized from conventional gypsum impression. A software was used to create the major connectors on digital impression datasets. After all the virtual major connectors designed from Group intraoral digital impressions (Group I) and Group extraoral digital impressions (Group E) were directly fabricated by 3D printing technique, the adaptation of the final major connectors in volunteers’ mouths were measured. The adaptation ranged from 159.87 to 577.99 μm in Group I while from 120.83 to 536.17 μm in Group E. The adaptation of major connectors in Group I were found better at the midline palatine suture while the adaptation of major connectors in Group E were found better at the two sides of the palatal vault. In both groups, the highest accuracy in adaptation was revealed at the anterior margin of the major connectors. It is feasible to manufacture the major connectors by digital impression and 3D printing technique. Both the adaptation of the two kinds of digital impressions were clinical acceptable.