bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asclepius and Hygieia in Dialectic: Philosophical, Ethical and Educational Foundations of an Integrative Medicine
Authors: Giordano James , Jonas Wayne 
Published: October 2017

In this essay, we posit that modern medicine, in its Asclepian focus, has subordinated the need and importance of Hygieian healing and caring, and in so doing has lost a quality that is essential to medicine, and fundamental to its lasting moral value. We argue that an integrative medicine must be based upon a core philosophical foundation that re-enjoins Asclepian and Hygieian approaches in true conceptual and practical dialectic, such that integration represents a synthesis of these orientations in epistemic, humanitarian and ethical domains. While we assert that a core philosophy is critical to the development and sustainability of an integrative medicine, such claims remain vacant in the absence of some meaningful attempt to put these concepts into action. We believe that to apply such philosophical foundations, an approach is necessary that simultaneously engages education, research, practice and policy. This involves not simply studying and co-opting new (or older, more ancient) modalities in a curative paradigm, but represents a paradigm shift that requires and is based upon understanding of, and skills for the application(s) of the most appropriate types of treatment(s) to affect disease, illness and health in a patient-centered model of care.
Assessment of clot length with multiphase CT angiography in patients with acute ischemic stroke
Authors: Polito Vanessa , La Piana Roberta , Del Pilar Cortes Maria , Tampieri Donatella 
Published: October 2017

Introduction Existing stroke literature demonstrates that rapid recanalization of vessels improves long-term prognosis after acute ischemic stroke. However, further optimization of the speed of the thrombectomy procedure, used to recanalize a blocked vessel, is limited by our minimal knowledge of the clot dimensions pre-procedure. Knowing the clot dimensions would allow planning of the thrombectomy procedure with the appropriate size and length of stent retriever, and determination of the correct site of the stent deployment ensuring total coverage of the clot by the stent retriever. Methods We performed a feasibility study to assess if multiphase computed tomography angiography (mCTA) can be used to estimate clot length by comparing CTA imaging data with imaging data obtained from conventional digital subtraction angiography (DSA). A retrospective chart review was performed of patients with clots in the proximal middle cerebral artery and adequate collateral circulation, who underwent both mCTA and DSA. Results Clot length was not significantly different on 3D mCTA versus mCTA MIPs, nor was it significantly different on MIP mCTA versus DSA. Pathological evidence also supported our ability to measure clot length on mCTA. Conclusions We suggest that mCTA is a reliable and valid measure of clot length in acute ischemic stroke patients.
Adverse Outcomes and Prediction of Cardiopulmonary Complications in Elective Spine Surgery
Authors: Passias Peter G. , Poorman Gregory W. , Delsole Edward , Zhou Peter L. , Horn Samantha R. , Jalai Cyrus M. , Vira Shaleen , Diebo Bassel , Lafage Virginie 
Published: October 2017

Study Design: Retrospective cohort study. Objectives: The purpose of this study was to report incidence of cardiopulmonary complications in elective spine surgery, demographic and surgical predictors, and outcomes. Understanding the risks and predictors of these sentinel events is important for risk evaluation, allocation of hospital resources, and counseling patients. Methods: A retrospective review of the National Surgical Quality Improvement Program (NSQIP) was performed on 60 964 patients undergoing elective spine surgery (any region; laminectomy, arthrodesis, discectomy, or laminoplasty) between 2011 and 2013. Incidence of myocardial infarction, cardiac arrest, unplanned reintubation, on ventilator >48 hours, perioperative pneumonia, and pulmonary embolism was measured. Demographic and surgical predictors of cardiopulmonary complications and associated outcomes (length of stay, discharge disposition, and mortality) were measured using binary logistic regression controlling for confounders. Results: Incidence rates per 1000 elective spine patients were 2.1 myocardial infarctions, 1.3 cardiac arrests, 4.3 unplanned intubations, 3.5 on ventilator >48 hours, 6.1 perioperative pneumonia, and 3.7 pulmonary embolisms. In analysis of procedure, diagnosis, and approach risk factors, thoracic cavity (odds ratio = 2.47; confidence interval = 1.95-3.12), scoliosis diagnosis, and combined approach (odds ratio = 1.51; confidence interval = 1.15-1.96) independently added the most risk for cardiopulmonary complication. Cardiac arrest had the highest mortality rate (34.57%). Being on ventilator greater than 48 hours resulted in the greatest increase to length of stay (17.58 days). Conclusions: Expected risk factors seen in the Revised Cardiac Risk Index were applicable in the context of spine surgery. Surgical planning should take into account patients who are at higher risk for cardiopulmonary complications and the implications they have on patient outcome.
Effects of daratumumab on natural killer cells and impact on clinical outcomes in relapsed or refractory multiple myeloma
Authors: Casneuf Tineke , Xu Xu Steven , Adams Homer C. , Axel Amy E. , Chiu Christopher , Khan Imran , Ahmadi Tahamtan , Yan Xiaoyu , Lonial Sagar , Plesner Torben , Lokhorst Henk M. , van de Donk Niels W. C. J. , Clemens Pamela L. , Sasser A. Kate 
Published: October 2017

Key PointsNK cells decline as daratumumab exposure increases in a maximum effect type dose-response relationship, with no efficacy and safety impact. Remaining PBMC cell fractions maintained the ability to carry out daratumumab-mediated ex vivo ADCC.
Strategy and the Strategist: How It Matters Who Develops the Strategy
Authors: Van den Steen Eric 
Published: October 2017

This paper addresses primarily two questions. First, when (and why) should a company’s strategy be developed by its CEO versus by some outside analyst or other insider? Second, how does strategy interact with vision (in the sense of a strong belief about the right course of action)? The paper studies these questions using a functional definition of strategy as “the smallest set of choices to optimally guide other choices.” Among other things, the paper shows that strategy formulation by the CEO leads to both better strategy and better execution, and that a strategist’s vision may improve execution. In the process, the paper also identifies criteria that make a decision strategic and derives explanations why strategies often reflect the background of the strategist. This paper was accepted by Bruno Cassiman, business strategy.
Performance evaluation of Hydrodynamic Vortex Separator at different hydraulic retention times applied in Recirculating Biofloc Technology system
Authors: Shi Mingming , Ruan Yunjie , Wu Binxin , Ye Zhangying , Zhu Songming 
Published: October 2017

Abstract. Recirculating biofloc technology (RBFT) has been gradually acknowledged for its positive effect on the control of biofloc concentration using a hydrodynamic vortex separator (HDVS). To operate an RBFT system at maximum performance, the removal efficiency of an HDVS at different hydraulic retention times (HRTs) must be fully predictable. Hence, a numerical study of the fluid flow and particle dynamics was performed to characterize the performance of an HDVS at varying HRTs. First, flow simulation was conducted to determine an economical mesh size at an HRT of 248 s. Then, with respect to the total suspended solids (TSS) in the RBFT system and the physical properties of the flocs, two-way coupling of the dense discrete phase model (DDPM) and discrete element model (DEM) methods was used to predict floc tracking in an HDVS. Additionally, the Reynolds averaged Navier-Stokes (RANS) equations with the Reynolds stress turbulence model (RSM) were solved using the finite volume method based on the semi-implicit method pressure-linked equations (SIMPLE) pressure correction algorithm in the computational domain. Finally, pilot-scale studies were conducted to verify the simulation models. Based on the simulation results, floc management in an RBFT system is briefly discussed. Due to limited research on the numerical simulation and operating conditions of an HDVS in an RBFT system, this article describes an original investigation of the modeling approach. Keywords: Computational fluid dynamics, Dense discrete phase model, Discrete element model, Floc management, Flow field, Removal efficiency, Total suspend solids.
Metalinguistic comments and multilingual awareness: Estonian-Russian language contacts in blogs
Authors: Verschik Anna 
Published: October 2017

AbstractThe paper focuses on the manifestation of multilingual awareness (MLA) and the impact of Estonian in Russian-language blogs by ethnic Russians. MLA can be defined as “an ability to focus on linguistic form and to switch focus between form and meaning” (Jessner, Ulrike. 2014. On multilingual awareness or why the multilingual learner is a specific language learner. In Miroslaw Pawlak & Larissa Aronin (eds.),Essential topics in applied linguistics and multilingualism. Studies in Honor of David Singleton, 175–184. Wien: Springer.). The purpose is to show that metalinguistic comments form as a subcategory of metalinguistic awareness, i.e., the latter conditions the former but not vice versa. I consider not only explicit examples of metalinguistic comments, such as discussion on differences between Russian of Russia and Russian in Estonia, proficiency in Estonian, sometimes including discussions on fine points of Estonian grammar, but also implicit and more subtle examples, such as visual separation of Estonian stems and Russian inflections, playful switches from Cyrillic to Latin characters and back within a sentence or even a word. All blogs are in the Live Journal environment, a medium which combines features of stand-alone blogs and social networks. The bloggers are reasonably proficient in Estonian and work or study in a predominantly Estonian-language environment. Data comes from fifteen blogs from the period 2008–2012. The bloggers position themselves as autonomous language users and consider blogs as their private virtual space with an individual language policy. This is in accordance with the views of some contact linguists (e.g., Thomason, Sara Grey. 2007. Language contact and deliberate change.Journal of Language Contact1. 41–62.), who consider change by deliberate decision as one of the mechanisms of contact-induced language change.
Word knowledge in academic literacy skills among collegiate ESL learners
Authors: Zhang Haomin , Xuan Winfred Wenhui 
Published: October 2017

Abstract
The study probed into the relationship between word knowledge and academic literacy skills in college-level English as a second language (ESL) learners. Morphological awareness and vocabulary knowledge were included in the word knowledge measures. In addition, reading comprehension and academic writing were the outcome variables. Using the data from 118 ESL students in Hong Kong, we found that both morphological awareness and vocabulary knowledge contributed to academic literacy skills. More important, direct and indirect effects of word knowledge on academic literacy skills were tested to provide insight into how two facets of word knowledge interact in shaping academic literacy acquisition. The results demonstrated that vocabulary knowledge mediated the relationship between morphological awareness and academic literacy skills. The study suggests that morphological sensitivity could enhance word meaning extraction and local meaning construction, which subsequently facilitates academic literacy skills.
Translanguaging in Yucatec Maya signing communities
Authors: Safar Josefina 
Published: October 2017

AbstractThis article looks at translanguaging practices in four Yucatec Maya communities with a high incidence of deafness in the peninsula of Yucatán, Mexico. Deaf and hearing community members draw from a broad spectrum of semiotic resources to interact with each other and with people from other villages in the region: they sign with different degrees of fluency, speak Yucatec Maya and/or Spanish, gesture, draw, point and incorporate objects in their physical surroundings. Human beings have a general tendency to communicate between and beyond different languages and modalities and to creatively adapt their semiotic repertoires to each other to negotiate meaning. On top of that, I show that sociolinguistic and cultural features of Yucatec Maya communities scaffold translanguaging practices. The rich inventory of conventional co-speech gestures of Yucatec Maya speakers, positive attitudes towards deafness and signed language and a critical amount of shared cultural knowledge facilitate communication between deaf and hearing and contribute to the emergence of similar sign languages in historically unrelated communities. The investigation of Yucatec Maya signing communities through a translanguaging lens allows us to critically deconstruct existing classifications of sign languages and varieties. Yucatec Maya Sign Languages are portrayed as a multi-layered network of different villages, families, generations and overlapping deaf and hearing spaces, where translanguaging takes place.
Effect of Preparation Method on Ag Modified Ti-HMS Catalyst Structure and Catalytic Oxidative Desulfurization Performance
Authors: Wang Fang , Wang Guangjian , Bing Liancheng , Wang Yong , Tian Aixiu , Yi Kaifeng 
Published: October 2017

Abstract
Ag modified mesoporous molecular sieves Ti-HMS were prepared by in-situ synthesis (Ag/Ti-HMS-I), deposition-precipitation method (Ag/Ti-HMS-D) and ultrasound-assisted impregnation methods (Ag/Ti-HMS-U), respectively. The catalytic performance of catalysts in the oxidative desulfurization(ODS) of benzothiophene with hydrogen peroxide (H2O2) has been investigated. The physicochemical properties of the catalysts were characterized by XRD, SEM, BET and FT-IR techniques. Experimental results showed that the catalyst Ag/Ti-HMS-U exhibited the best catalytic activity, and this maybe because the catalyst possessed relatively good mesoporous structure and high Ag dispersion. Under the best operating condition for the catalytic oxidative desulfurization: temperature 60 °C, atmospheric pressure, 0.1 g catalysts, 8 molar ratio of hydrogen peroxide to sulfur, using acetonitrile as extraction solvent for double extraction, the sulfur content in model diesel fuel (MDF) was reduced from 800 ppm to 17 ppm with 97.8% of total sulfur after 1 h.
Yogic practices on oxidative stress and of antioxidant level: a systematic review of randomized controlled trials
Authors: Pal Rameswar , Gupta Navin 
Published: October 2017

Abstract

Background
Many clinical trials have evaluated the oxidative stress reduction and enhancement of antioxidant status following yogic practices, but a review has not been reported earlier. Present study is designed to systematically review the effect of yogic practices on oxidative stress and antioxidant status.

Content
Using the MEDLINE, EMBASE SCOPEMED, and Indian database electronic searches were performed through August 2016 using the keywords yoga AND oxidative stress OR antioxidant which yielded 97 studies. Selections were made to include only experimental studies written in English, published in peer-reviewed journals and investigating the effects of regular yogic practices on oxidative stress and antioxidant status in these studies.

Summary and outlook
Search yielded a total of 97 trials, 11 met rigorous criteria for final systematic review. Healthy population showed overall enhancement of antioxidant status and reduced oxidative stress following yogic practices. Diabetic patients showed increased glutathione, vitamin C content and superoxide dismutase activity and decreased malondialdehyde content following yogic practices. Prediabetic and hypertensive patients showed reduced malondialdehyde content following yogic practices. Renal disease patients showed decreased protein oxidation, and increased superoxide dismutase activity following yogic practices. Regular yogic practices can improve antioxidants and reduce oxidative stress in healthy, diabetic, prediabetic, hypertensive and renal disease patients. Studies on other disease population have rarely been reported and studies are very few to conclude strongly.
Substation Equipment 3D Identification Based on KNN Classification of Subspace Feature Vector
Authors: Guo Weiying , Ji Yong , Luo Yong , Zhou Yan 
Published: October 2017

Abstract
Aiming to realize rapid and efficient three-dimensional (3D) identification of substation equipment, this article proposes a new method in which the 3D identification of substation equipment is based on K-nearest neighbor (KNN) classification of subspace feature vector. First of all, the article uses octree encoding to reduce and denoise the point cloud data obtained by a 3D laser scanner. Secondly, position calibration and size standardization are used for the point cloud after pretreatment. Then, the normalized point cloud is divided into a number of cubes with same size. The cosine of the angle between the positive direction of z axis and a vector from the global centroid of the point cloud to the centroid of each subspace is regarded as the feature of the subspace. All cosines of subspaces constitute the feature of the point cloud. Finally, we classify the subspace feature vector by using the KNN algorithm and improve classification accuracy by using the particle swarm optimization algorithm. The simulation results show that the identification accuracy of the proposed method for unknown substation equipment is about 90% and the proposed method is applicable to low-degree losses. Apparently, this method can accurately identify 3D substation equipment. At the same time, increasing the number of subspaces will improve the accuracy; however, it will increase the recognition time.
Transfusion-associated necrotizing enterocolitis re-evaluated: a systematic review and meta-analysis
Authors: Rai Stientje Esther , Sidhu Amneet Kaur , Krishnan Rohin Jayaram 
Published: October 2017

AbstractContext:Significant controversy exists surrounding the possible association between recent packed red blood cell (PRBC) transfusion and the subsequent development of necrotizing enterocolitis (NEC) in infants. Previous studies and meta-analyses reporting a statistically significant association led to a practice change to withhold enteral feeds in the peri-transfusion period in many centers in an effort to prevent NEC; however, results from more recent studies do not support the existence of an association and, thus, question the validity of this practice change.Objective:This study aimed to perform a systematic review and meta-analysis to determine whether exposure to recent PRBC transfusion (defined as within 48 h) is associated with the subsequent development of NEC stage ≥II (Bell’s criteria) in infants.Methods:Medline, Embase, CINAHL, and the Cochrane Library were searched from inception to October 7, 2015. A gray literature search was also performed. Studies comparing the risk of NEC in infants exposed and unexposed to recent PRBC transfusion were included. Thirteen studies met eligibility criteria, and 10 (n=15,675 infants) were included in the meta-analysis. Three authors independently extracted data, and meta-analysis was performed using a random effects model.Results:We found a statistically significant 45% reduction in the unadjusted odds of NEC in infants exposed to a recent PRBC transfusion (odds ratio=0.55, 95% confidence interval=0.31–0.98).Conclusion:Our results show a protective effect of recent PRBC transfusion on the subsequent development of NEC. The practice of withholding enteral feeds during the peri-transfusion period should be re-evaluated in light of these results.
Procedural Delay in the Developing Middle East
Authors: Economides Kim 
Published: October 2017

AbstractIn this article, I explore whether and how Middle Eastern legal process can be reconciled with the idea of timeliness. The idea that any procedure physically within the Gulf Cooperation Council (GCC) and Middle East and North Africa (MENA) regions could be both fair and expeditious may appear counterintuitive to those brought up in the Anglo-American legal tradition, and the suggestion that there could exist a notion of “timely Middle Eastern procedure” that produced just and fair results is more than likely to be treated as an oxymoron. Administrative, political and legal processes throughout the Levant and Arab world are, when viewed through Western eyes, more than likely to be characterised as corrupt, slow or even Kafkaesque. I argue that procedural delay is an inherently problematic and relative concept, both legally and culturally speaking, which cannot make sense without introducing robust time standards against which court processing time can be evaluated. I seek to elucidate the fundamental nature and causes of procedural delay in relation to civil trials and propose the adoption of a distinct methodology that could be used to more objectively assess court efficiency in handling civil cases throughout the GCC and MENA regions.
(Dicyclohexyl(2-(dimesitylboryl)phenyl)phosphine: en route to stable frustrated Lewis pairs-hydrogen adducts in water
Authors: Sorochkina Kristina , Chernichenko Konstantin , Nieger Martin , Leskelä Markku , Repo Timo 
Published: October 2017

Abstract
The new ansa-phosphinoborane (dicyclohexyl(2-(dimesitylboryl)phenyl)phosphine was synthesized via an one-pot protocol in 67% yield. The compound has been characterized by 1H, 13C, 11B and 31P NMR, and its solid-state structure determined by a single crystal X-ray diffraction analysis. The ansa-phosphinoborane does not react with molecular hydrogen or water at room or elevated temperature. According to performed DFT studies, heterolytic splitting of water or hydrogen by the phosphinoborane are both endergonic but close in thermodynamics. In polar solvents, such as in methanol or acetonitrile, addition of hydrogen is energetically more favorable than of water.