bluuebunny/crossref_metadata_2025_split huggingface dataset:
ChemInform Abstract: TOTAL SYNTHESIS OF (.+‐.)‐FURANOEREMOPHILANE‐3,6‐DIONE AND (.+‐.)‐LIGULARONE BY A ROUTE INVOLVING ALKYLATION OF 2,4‐DIMETHYL‐3‐FUROIC ACID
Authors: TADA M. , SUGIMOTO Y. , TAKAHASHI T. 
Published: April 2016

AbstractDas durch Kondensation der Furancarbonsäure (I) mit dem Methoxycyclohexenon (II) zugängliche Furylmethylcyclohexenon (III) wird nach katalytischer Hydrierung säurekatalytisch zum Furanodecalindion (IV) cyclisiert.
ChemInform Abstract: A SIMPLE SYNNTHESIS OF 2‐ACYL INDOLES FROM ISATINS
Authors: BLACK D. S. C. , WONG L. C. H. 
Published: April 2016

AbstractDie Isatine (I) werden zu den Natriumcarboxylaten (II) gespalten, die zu den N‐substituierten Isatinen (IV) alkyliert werden.
ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF 3‐AMINOMETHYL DERIVATIVES OF SOME 5‐ARYL‐1,3,4‐OXADIAZOL‐2‐ONES
Authors: MAZZONE G. , BONINA F. , ARRIGO REINA R. 
Published: April 2016

AbstractDie Oxadiazolone (I) reagieren mit Formaldehyd/Aminen zu den Mannich‐basen (II) bzw. (III).
ChemInform Abstract: SYNTHESIS AND CONFORMATIONAL ANALYSIS OF 7,8‐DIPHENYL‐1,3,4,6,9,9A‐HEXAHYDRO‐2H‐QUINOLIZINES
Authors: TRIGO G. G. , GALVEZ E. , SOELLHUBER M. M. 
Published: April 2016

AbstractAus den Benzaldehyden (I) erhält man mit Z‐Picolyllithium (II) die Carbinole (III), die zu den Piperidinen (IV) hydriert und zu (V) oxidiert werden.
ChemInform Abstract: A NEW SYNTHESIS OF 3H‐PHENOXAZIN‐3‐ONES
Authors: BIRD C. W. , LATIF M. 
Published: April 2016

AbstractDie Diphenylether (I) und (III) (dargestellt durch Kondensation von o‐Chlor‐nitrobenzolen mit Resorcinderivaten) werden reduktiv direkt bzw. über die Hydroxyphenoxazine (IV) zu den Phenoxazinonen (II) bzw. (V) cyclisiert.
ChemInform Abstract: STUDY OF THE CHEMISTRY OF PHENOXAZINES. 12. REACTION OF 2‐SUBSTITUTED PHENOXAZIN‐3‐ONES WITH THIOPHENOLS
Authors: AFANAS'EVA G. B. , VIKTOROVA T. S. , POSTOVSKII I. YA. , BIL'KIS I. I. , SHEIN S. M. 
Published: April 2016

AbstractDas Ethoxyphenoxazinon (I) reagiert in Gegenwart von Salzsäure mit p‐Thiokresol (II) zu einem Gemisch der Tolylthioderivate (III) und (IV).
ChemInform Abstract: INTRA‐ AND INTERMOLECULAR CYCLIZATION OF OLEFINIC TOSYLHYDRAZONES UNDER ACIDIC CONDITIONS. A FACILE SYNTHESIS OF BICYCLIC AZOALKANES
Authors: WILSON R. M. , REKERS J. W. , PACKARD A. B. , ELDER R. C. 
Published: April 2016

AbstractBehandlung der Tosylhydrazone (IIa)‐(IId) mit BF3 ‐etherat führt zur Cyclisierung unter Bildung der bislang unzugänglichen Bicycloazoalkane (III) [ leichtere Bildung von (IIIa), (IIIb) gegen‐ über (IIIc), (IIId)]; neben (IIIc) wird außerdem das intermolekulare Kondensations‐ produkt (IV) isoliert.
ChemInform Abstract: PHOTOCYCLOADDITION OF 3‐ACETOXYBENZO(B)THIOPHENE 1,1‐DIOXIDE TO CYCLOALKENES; A NOVEL SYNTHESIS OF SUBSTITUTED BENZO(B)THIEPINONES
Authors: KIRBY N. V. , REID S. T. 
Published: April 2016

AbstractDas Benzothiophendioxid (I) reagiert mit Cyclohexen zum Cycloaddukt (III), das in Gegenwart von Alkali unter Ringerweiterung zum Benzothiepinon (IV) führt.
ChemInform Abstract: 3,3,7,7‐BIS(10′‐METHYL‐9′,9′‐ACRIDANYL)‐1,2,5,6‐TETRAOXOCANE, A DIOXETANE DIMER, FROM THE REACTION OF 10‐METHYL‐9‐METHYLENE‐9,10‐ACRIDAN WITH SINGLET OXYGEN
Authors: WHITE E. H. , SUZUKI N. , HENDRICKSON W. H. 
Published: April 2016

AbstractDie durch Methylenblau sensibilisierte Photooxidation des Methylenacridans (I) führt über das Spirodioxetan (II) und das ringgeöffnete Peroxobetain (III) zum dimeren Spiroperoxid (IV) und dem Acridon (V).
ChemInform Abstract: REACTIONS OF BORON TRICHLORIDES WITH SILYLAMINES CONTAINING SILICON‐HYDROGEN BONDS
Authors: NEILSON R. H. 
Published: April 2016

AbstractReaktionen von B‐ trichlorid mit Di‐ und Trisilylaminen, die mindestens eine Si‐H‐Bindung enthalten, werden untersucht.
ChemInform Abstract: METAL‐NITROXYL INTERACTIONS. 17. SPIN‐LABELED ADDUCTS OF BIS(HEXAFLUOROACETYLACETONATO)COPPER(II)
Authors: BOYMEL P. M. , BRADEN G. A. , EATON G. R. , EATON S. S. 
Published: April 2016

AbstractDurch Kondensation von Pyridincarbaldehyden mit Pyrrolidin‐ 1‐oxy‐Derivaten wurden die spin‐markierten Liganden (I) und (II) dargestellt.
ChemInform Abstract: PHOSPHOLES AS LIGANDS: PALLADIUM(II) COMPLEXES OF 1‐SUBSTITUTED 3,4‐DIMETHYLPHOSPHOLES. STRUCTURE AND PROPERTIES
Authors: MACDOUGALL J. J. , NELSON J. H. , MATHEY F. , MAYERLE J. J. 
Published: April 2016

AbstractDie 1:2‐molare Umsetzung von Dichlorobis‐ [benzonitril]‐Pd mit den Phospholen unter N2 in Benzol führt zu den Dichloro‐bis‐ [phosphol]‐Komplexen (I) (X: C1), aus denen die Dibromo‐ und Diazido‐Analogen durch metathetische Reaktion mit NaBr oder NaN3 in Methanol/Chloroform darstellbar sind.
ChemInform Abstract: TOTAL SYNTHESIS OF (.+‐.)‐5.BETA‐,8α‐ANDROST‐9(11)‐ENE‐3,17‐DIONE
Authors: KAKUSHIMA M. , ALLAIN L. , DICKINSON R. A. , WHITE P. S. , VALENTA Z. 
Published: April 2016

AbstractDie SnCl4‐katalysierte Diels‐Alder‐Reaktion der Komponenten (I) und (II) liefert ein Gemisch vier isomerer Cycloaddukte, in dem das Isomere (III) überwiegt (55‐65% Anteil am Gemisch).
ChemInform Abstract: SYNTHESIS OF PYRAZINE DERIVATIVES OF STEROID KETONES ‐ STEROID DIHYDROPYRAZIN‐5′‐ONES
Authors: VOLOVEL'SKII L. N. , POPOVA N. V. , YAKOVLEVA M. YA. , KOROTKOV S. A. , SHNEUR V. N. 
Published: April 2016

AbstractSteroid‐dihydro‐pyrazin‐5′‐one.
ChemInform Abstract: THE METHYL GROUP AS PHOSPHATE PROTECTING GROUP IN NUCLEOTIDE SYNTHESES
Authors: SMITH D. J. H. , OGILVIE K. K. , GILLEN M. F. 
Published: April 2016

AbstractAus dem Nucleosid (I) erhält man durch stufenweise Umsetzung mit dem Chlorid (II), Alkoholen und Iod den Ester (III), aus dem über das Derivat (IVa) nach Hydrolyse zu (IVb) in tert.‐Butylamin das Folgeprodukt (IVc) entsteht.
ChemInform Abstract: PREPARATION OF LEVODOPA BY BIOCONVERSIONS
Authors: NINET L. , RENAUT J. 
Published: April 2016

AbstractReview: Für die industrielle Gewinnung von Levodopa(L‐2,3‐Dihydroxy‐phenylalanin) ‐ einem wirksamen Antiparkinson‐ Agens ‐ werden mehrere Bioumwandlungsmethoden vorgeschlagen.
ChemInform Abstract: INDOLE DERIVATIVES. 119. C‐ACYLATION OF METHYL (INDOL‐3‐YL)ACETATE. SYNTHESIS OF 5‐(INDOL‐3‐YL)PYRIMIDINES
Authors: ROZHKOV V. S. , SMUSHKEVICH YU. I. , SUVOROV N. N. 
Published: April 2016

AbstractDie Claisen‐Kondensation des Indolylessigsäuremethylesters (I) mit Dimethylcarbonat (II), Benzoesäuremethylester (V), Ameisensäuremethylester (VII) und Essigsäuremethylester (XV) erfolgt unter Acylierung an der CH2‐Gruppe.
Multi‐scale simulation of falling film short‐path distillation
Authors: Zhu Dong , Huang Feng‐Xia , Xu Song‐Lin , Li Yang 
Published: April 2016

AbstractThis study investigated issues relating to the multi‐scale simulation of falling film short‐path distillation. Both hydrodynamic conditions and gas phase kinetics have a considerable effect on the distillation process. At the micro‐scale, the DSMC (direct simulation Monte Carlo) method was adopted. Both molecular rotation and translation have been taken into account, and we obtained the temperature distribution along the distillation gap. At the meso‐scale, we used Excel as a bridge between the micro‐scale and macro‐scale. We obtained the evaporation efficiency for different temperatures. At the macro‐scale, the evaporation efficiency was used to modify the Langmuir equation, then the modified Langmuir equation was written into the mass transfer source. We used Fluent to carry out the numerical simulation. Thus, the gas phase and liquid phase were coupled. Only considering the gas phase and neglecting any surface wave in the liquid film leads to inaccurate results; this paper makes up for past deficiencies. It is found that the evaporating temperature, condensing temperature, and distillation gap have significant effects on the temperature distribution in the gas phase. The heat and mass transfer processes are correlated with the interfacial vorticity. To quantitatively describe the relation between the interfacial vorticity and concentration in the interface, we proposed a correlation coefficient. It is also observed that the average value ofis 0.63, and the local maximum value ofis usually located in the region of the wave trough.
Quantitative imaging for development of companion diagnostics to drugs targeting HGF/MET
Authors: Huang Fangjin , Ma Zhaoxuan , Pollan Sara , Yuan Xiaopu , Swartwood Steven , Gertych Arkadiusz , Rodriguez Maria , Mallick Jayati , Bhele Sanica , Guindi Maha , Dhall Deepti , Walts Ann E , Bose Shikha , de Peralta Venturina Mariza , Marchevsky Alberto M , Luthringer Daniel J , Feller Stephan M , Berman Benjamin , Freeman Michael R , Alvord W Gregory , Vande Woude George , Amin Mahul B , Knudsen Beatrice S 
Published: April 2016

AbstractThe limited clinical success of anti‐HGF/MET drugs can be attributed to the lack of predictive biomarkers that adequately select patients for treatment. We demonstrate here that quantitative digital imaging of formalin fixed paraffin embedded tissues stained by immunohistochemistry can be used to measure signals from weakly staining antibodies and provides new opportunities to develop assays for detection of MET receptor activity. To establish a biomarker panel of MET activation, we employed seven antibodies measuring protein expression in the HGF/MET pathway in 20 cases and up to 80 cores from 18 human cancer types. The antibodies bind to epitopes in the extra (EC)‐ and intracellular (IC) domains of MET (MET4EC, SP44_METIC, D1C2_METIC), to MET‐pY1234/pY1235, a marker of MET kinase activation, as well as to HGF, pSFK or pMAPK. Expression of HGF was determined in tumour cells (T_HGF) as well as in stroma surrounding cancer (St_HGF). Remarkably, MET4EC correlated more strongly with pMET (r = 0.47) than SP44_METIC (r = 0.21) or D1C2_METIC (r = 0.08) across 18 cancer types. In addition, correlation coefficients of pMET and T_HGF (r = 0.38) and pMET and pSFK (r = 0.56) were high. Prediction models of MET activation reveal cancer‐type specific differences in performance of MET4EC, SP44_METIC and anti‐HGF antibodies. Thus, we conclude that assays to predict the response to HGF/MET inhibitors require a cancer‐type specific antibody selection and should be developed in those cancer types in which they are employed clinically.
Masonry buildings at the borderline to high‐rise – Part 1 / Mauerwerksbauten an der Hochhausgrenze – Teil 1
Authors: Seim Werner , Sommerlade Kai 
Published: April 2016

AbstractThe interaction of vertical and horizontal loads is the decisive combination of actions for multi‐storey buildings with masonry shear walls in most cases. This article presents a simple and clear method, which can be used with modern open floor plans to verify a favourable load transfer of the vertical actions for masonry walls. The method is extended in the second part of the article to be published in one of the coming issues of the journal Mauerwerk for horizontal actions and explained with an example.
Installing windows in composite thermal insulation systems / Fenstermontage in Wärmedämm‐Verbundsystemen
Authors: Jehl Wolfgang , Benitz‐Wildenburg Jürgen 
Published: April 2016

AbstractAccording to the German Association for Composite Thermal Insulation Systems, about 780 million m² of composite thermal insulation systems (ETICS) have up to now been installed in both existing and new buildings in Germany − a trend that is set to continue. Correct window installation in ETICS with a permanent and functional connection to the building fabric requires architects, engineers and contractors to be familiar with the special details of this external wall system [1], [2]. However, experience from expert witness reporting has shown that this is frequently not so and that eliminating any defects subsequently is only possible at great expense.
Sztynort Palace – Damage, repair and contemporary adaptations / Schloss Steinort – Schäden, Sicherung und modellhafte Adaption
Authors: Boekhoff Beate 
Published: April 2016

AbstractThe model project financed by the Deutsche Bundesstiftung Umwelt (German Federal Environmental Foundation) to repair anthropogenic foundation damage to Sztynort Palace was implemented in 2014/15 with the active participation of the Chair for Structural Design of the TU Dresden and thus achieved an exemplary adaptation of the house to future changes of environmental conditions. In addition to securing of the masonry of the northwest tower, which had been severely damaged by settlement, and further technically challenging refurbishment works to the partially collapsed cellar vaults, above all innovative solutions were planned, optimized and implemented to install an effective and modern drainage and rain water management system to the historic house with its complex construction.
Development of High‐Power Density Interleaved dc/dc Converter with SiC Devices
Authors: KITAMURA TATSUYA , YAMADA MASAKI , HARADA SHIGEKI , KOYAMA MASATO 
Published: April 2016

SUMMARYWe developed an interleaved dc/dc converter with SiC devices. We applied full‐SiC modules including MOSFETs and SBDs to the interleaved dc/dc converter to achieve a high‐power density. An SiC has a high temperature resistance, which facilitates an improvement in high‐frequency drives. We achieved a high‐power density by utilizing this high temperature resistance. We also fabricated a prototype and tested it with loads up to 65 kW.
An Electrical Energy Allotment Method for a Large Railway Network
Authors: KOMAKI DAISUKE , YANO KOJIN , FUKUMOTO TAKASHI 
Published: April 2016

SUMMARYRailway operators usually do not consider the limit of the electrical energy supply in Japan. Although technologies have been developed for energy efficiency, the limit on the available electrical energy is not considered. However, railway operators met the limit in summer 2011 after the earthquake off the Pacific coast of Tohoku. In this study, we develop an electrical energy allotment method for a large railway network. The method optimizes train operations to provide better railway service when the energy supply is limited. We also develop a search method to find the optimal operation from very large combinations of operation factors. These optimization and search methods are evaluated using the Tohoku earthquake scenario.
Ce/Au(CN)2–‐Based Coordination Polymers Containing and Lacking Aurophilic Interactions
Authors: Roberts Ryan J. , Ahern John C. , Patterson Howard H. , Leznoff Daniel B. 
Published: April 2016

AbstractNew members of the Ln[Au(CN)2]3·3H2O and [nBu4N]2[Ln(NO3)4Au(CN)2] series Ln = Ce (CeAu3and CeAu respectively) are reported herein where their synthesis, structure and photoluminescence properties are discussed. The first is a 3‐D coordination polymer with aurophilic interactions of 3.35 Å and the latter is a 1‐D coordination polymer that lacks them. At 293 K both CeAu3and CeAu display characteristic CeIII‐based emission atλmax= 393 nm (5d→2FJ), however in CeAu3AuI‐based emission (λmax= 410,1MLCT) dominates the spectrum. At 77 K however, the dominant emission is AuI‐based with characteristic emissions ofλmax= 430 nm (1MLCT) and 490 nm (3MLCT). The key difference in the luminescence of these two materials can be rationalized in terms of their respective structures, through either the aurophilic network and lack thereof and/or the rigidity offered in the 3‐D structure of CeAu3.
Increased pain and muscle glutamate concentration after single ingestion of monosodium glutamate by myofascial temporomandibular disorders patients
Authors: Shimada A. , Castrillon E.E. , Baad‐Hansen L. , Ghafouri B. , Gerdle B. , Wåhlén K. , Ernberg M. , Cairns B.E. , Svensson P. 
Published: April 2016

AbstractBackgroundA randomized, double‐blinded, placebo‐controlled study was conducted to investigate if single monosodium glutamate (MSG) administration would elevate muscle/serum glutamate concentrations and affect muscle pain sensitivity in myofascial temporomandibular disorders (TMD) patients more than in healthy individuals.MethodsTwelve myofascial TMD patients and 12 sex‐ and age‐matched healthy controls participated in two sessions. Participants drank MSG (150 mg/kg) or NaCl (24 mg/kg; control) diluted in 400 mL of soda. The concentration of glutamate in the masseter muscle, blood plasma and saliva was determined before and after the ingestion of MSG or control. At baseline and every 15 min after the ingestion, pain intensity was scored on a 0–10 numeric rating scale. Pressure pain threshold, pressure pain tolerance (PPTol) and autonomic parameters were measured. All participants were asked to report adverse effects after the ingestion.ResultsIn TMD, interstitial glutamate concentration was significantly greater after the MSG ingestion when compared with healthy controls. TMD reported a mean pain intensity of 2.8/10 at baseline, which significantly increased by 40% 30 min post MSG ingestion. At baseline, TMD showed lower PPTols in the masseter and trapezius, and higher diastolic blood pressure and heart rate than healthy controls. The MSG ingestion resulted in reports of headache by half of the TMD and healthy controls, respectively.ConclusionThese findings suggest that myofascial TMD patients may be particularly sensitive to the effects of ingested MSG.What does this study add?’

Elevation of interstitial glutamate concentration in the masseter muscle caused by monosodium glutamate (MSG) ingestion was significantly greater in myofascial myofascial temporomandibular disorders (TMD) patients than healthy individuals.

This elevation of interstitial glutamate concentration in the masseter muscle significantly increased the intensity of spontaneous pain in myofascial TMD patients.
Multi‐stage high order semi‐Lagrangian schemes for incompressible flows in Cartesian geometries
Authors: Cameron Alexandre , Raynaud Raphaël , Dormy Emmanuel 
Published: April 2016

SummaryEfficient transport algorithms are essential to the numerical resolution of incompressible fluid‐flow problems. Semi‐Lagrangian methods are widely used in grid based methods to achieve this aim. The accuracy of the interpolation strategy then determines the properties of the scheme. We introduce a simple multi‐stage procedure, which can easily be used to increase the order of accuracy of a code based on multilinear interpolations. This approach is an extension of a corrective algorithm introduced by Dupont & Liu (2003, 2007). This multi‐stage procedure can be easily implemented in existing parallel codes using a domain decomposition strategy, as the communication pattern is identical to that of the multilinear scheme. We show how a combination of a forward and backward error correction can provide a third‐order accurate scheme, thus significantly reducing diffusive effects while retaining a non‐dispersive leading error term. Copyright © 2016 John Wiley & Sons, Ltd.
Correlated inter‐regional variations in low frequency local field potentials and resting state BOLD signals within S1 cortex of monkeys
Authors: Wilson George H. , Yang Pai‐Feng , Gore John C. , Chen Li Min 
Published: April 2016

AbstractThe hypothesis that specific frequency components of the spontaneous local field potentials (LFPs) underlie low frequency fluctuations of resting state fMRI (rsfMRI) signals was tested. The previous analyses of rsfMRI signals revealed differential inter‐regional correlations among areas 3a, 3b, and 1 of primary somatosensory cortex (S1) in anesthetized monkeys (Wang et al. [2013]: Neuron 78:1116–1126). Here LFP band(s) which correlated between S1 regions, and how these inter‐regional correlation differences covaried with rsfMRI signals were examined. LFP signals were filtered into seven bands (delta, theta, alpha, beta, gamma low, gamma high, and gamma very high), and then a Hilbert transformation was applied to obtain measures of instantaneous amplitudes and temporal lags between regions of interest (ROI) digit–digit pairs (areas 3b–area 1, area 3a–area 1, area 3a–area 3b) and digit–face pairs (area 3b–face, area 1–face, and area 3a–face). It was found that variations in the inter‐regional correlation strengths between digit–digit and digit–face pairs in the delta (1–4 Hz), alpha (9–14 Hz), beta (15–30 Hz), and gamma (31–50 Hz) bands parallel those of rsfMRI signals to varying degrees. Temporal lags between digit–digit area pairs varied across LFP bands, with area 3a mostly leading areas 1/2 and 3b. In summary, the data demonstrates that the low and middle frequency range (1–50 Hz) of spontaneous LFP signals similarly covary with the low frequency fluctuations of rsfMRI signals within local circuits of S1, supporting a neuronal electrophysiological basis of rsfMRI signals. Inter‐areal LFP temporal lag differences provided novel insights into the directionality of information flow among S1 areas at rest. Hum Brain Mapp 37:2755–2766, 2016. © 2016 Wiley Periodicals, Inc.
Label‐free in vivo cellular‐level detection and imaging of apoptosis
Authors: Bower Andrew J. , Marjanovic Marina , Zhao Youbo , Li Joanne , Chaney Eric J. , Boppart Stephen A. 
Published: April 2016

Cell death plays a critical role in health and homeostasis as well as in the pathogenesis and treatment of a broad spectrum of diseases and can be broadly divided into two main categories: apoptosis, or programmed cell death, and necrosis, or acute cell death. While these processes have been characterized extensively in vitro, label‐free detection of apoptosis and necrosis at the cellular level in vivo has yet to be shown. In this study, for the first time, fluorescence lifetime imaging microscopy (FLIM) of intracellular reduced nicotinamide adenine dinucleotide (NADH) was utilized to assess the metabolic response of in vivo mouse epidermal keratinocytes following induction of apoptosis and necrosis. Results show significantly elevated levels of both the mean lifetime of NADH and the intracellular ratio of protein bound‐to‐free NADH in the apoptotic compared to the necrotic tissue. In addition, the longitudinal profiles of these two cell death processes show remarkable differences. By identifying and extracting these temporal metabolic signatures, apoptosis in single cells can be studied in native tissue environments within the living organism.
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Induction of neuronal activation by femtosecond‐pulsed laser irradiation and its potential application for amyloid‐β–induced toxicity assessment
Authors: Lee Seunghee , Yoon Jonghee , Choi Myunghwan , Choi Chulhee 
Published: April 2016

Manipulating neural activity is crucial for studying the neural connectivity and the pathophysiology of neurodegenerative disease. Among various techniques for neural activation, direct optical stimulation method with femtosecond‐pulsed laser is simple and can be specifically applied on a single neuron. Brief irradiation of femtosecond laser pulses on a neuron elevates intracellular calcium, and it propagates to adjacent neurons. However, the mechanisms of laser‐induced neural activation are still unclear. In this report, we have elucidated the mechanism of laser‐induced neural activation which could be mediated by superoxide, specifically blocked by diphenyleneiodonium chloride, and depletion in intracellular calcium storage. Furthermore, we also showed that the propagation of calcium initiated by laser stimulation is dependent on the presence of extracellular calcium as well as electrical and chemical synapses. We verified the applicability of such mechanism for the assessment of neuronal functionality, by measuring calcium elevation, intracellular calcium propagation, ROS increase, and performing cell death assay in vehicle and Aβ‐treated neurons. This work suggests promising applications of the potential for implementing such laser‐induced neural activation for rapid and reliable drug screening.
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