bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of knowledge management on job performance in higher education
Authors: Masa’deh Ra’ed , Shannak Rifat , Maqableh Mahmoud , Tarhini Ali 
Published: February 2017

Purpose
This is an empirical study of knowledge management performance (KMP) at a university and the purpose of this paper is to examine the relationship between knowledge management process (KMPR), KMP and job performance (JP).

Design/methodology/approach
The data were collected using a questionnaire, as the instrument for the primary data collection, with total collected back responses of 207 from university lecturers who have actually participated. Structural equation modeling technique was used to fully analyze the data in order to determine what level of the relationship between knowledge management (KM) and JP existed.

Findings
The main findings were related to confirming the two main hypotheses of the research that were related to testing if there were relationships between the KMPR (represented by seven surrogate measures, namely, knowledge identification, knowledge creation, knowledge collection, knowledge organizing, knowledge storage, knowledge dissemination and knowledge application) and KMP, as well as if the KMP was related to the JP.

Originality/value
This paper focuses on investigating the actual role of KM at a university, which is assumingly a knowledge factory. Contrary to the conventional wisdom that presumes the importance of KM and specially when there is no proper KM regiment in place, the paper reports the limited influence KM has on staff JP. It is one of the few studies that fills the gap in the literature concerned with the relationship between KM and JP and perhaps the first to provide insights about the KM intricacies at a Jordanian University.
Enabling internet banking adoption
Authors: Marakarkandy Bijith , Yajnik Nilay , Dasgupta Chandan 
Published: February 2017

Purpose
The integration of relevant antecedents into TAM would lead to better understanding of the decision factors which act as enablers for the adoption of internet banking. The purpose of the paper is to determine the influence of the antecedents subjective norm, image, banks initiative, internet banking self-efficacy, internet usage efficacy, trust, perceived risk, trialability and government support on the existing constructs of the technology acceptance model (TAM) and to test measurement invariance and the moderating effect of the demographic variables on the relationship between the latent constructs used in this augmented TAM.

Design/methodology/approach
A survey questionnaire was administered on internet banking users and a total of 300 responses were collected. A two-step approach suggested by Hair et al. (2006) and Schumacker and Lomax (2004) was used in this study. The proposed model was assessed using the confirmatory factor analysis approach. The structural model was then tested in order to establish nomological validity. The data based on four demographic dimensions gender, age, income, education were divided into two groups for each of these demographic dimensions. The invariance test was first performed on the measurement model and then on the structural model. The measurement model and structural model were subjected to tests of equivalence of parameters across groups.

Findings
To a large extent the results of the study supports the proposed model and thereby contributes to understand the influence of subjective norm, image, banks initiative, internet banking self-efficacy, internet usage efficacy, trust, perceived risk and government support on internet banking adoption. The predictor variables in the augmented TAM were able to explain 29.9 per cent of the variance in the actual usage of internet banking as compared to the TAM which was able to explain only 26.5 per cent variance in the actual usage of internet banking. A significant difference in the relationship between the different constructs of the model was observed when the model was subjected to multi-group invariance testing.

Research limitations/implications
The study suffers from the same limitations as most other studies involving TAM. In this study self-reported measures about the usage were taken as the actual usage. The findings of the study can be of use to marketers for target-specific marketing by customizing the marketing campaign focussing on the factors that were found to be strong influencers leading to the usage of internet banking for each target audience.

Originality/value
The main challenge in this study was to develop the conceptual model for the internet banking adoption by extending the TAM and to get a robust theoretical support from the extant literature for the relevant factors along with their relationship to uncover new insights about factors responsible for the internet banking adoption. The augmented model had an improved predictive capability and explanatory utility.
Stanley Hollander’s T-shirt test: where marketing history meets psychogeography
Authors: Brown Stephen 
Published: February 2017

Purpose
The aim of this overview is to reflect on the family resemblances between psychogeography and marketing history.

Design/methodology/approach
The paper is informally predicated on the perspectives and philosophies of literary theory in general and New Historicism in particular.

Findings
Using exemplar excerpts from salient published works, marketing’s hitherto overlooked psychogeographical traditions are contemplated and celebrated, the sterling contributions of Stanley C. Hollander above all.

Research limitations/implications
Like poets who don’t know it, marketing historians are unsung contributors to the psychogeographical corpus. There is much more that can be done, however, especially in relation to works of imaginative literature.

Originality/value
This paper aims to uncover past achievements not advance the future agenda.
The Griffiths Question Map: A Forensic Tool For Expert Witnesses’ Assessments of Witnesses and Victims’ Statements
Authors: Dodier Olivier , Denault Vincent 
Published: February 2017

AbstractExpert witnesses are sometimes asked to assess the reliability of young witnesses and victims’ statements because of their high susceptibility to memory biases. This technical note aims to highlight the relevance of the Griffiths Question Map (GQM) as a professional forensic tool to improve expert witnesses’ assessments of young witnesses and victims’ testimonies. To do so, this innovative question type assessment grid was used to proceed to an in‐depth analysis of the interview of an alleged 13‐year‐old victim of a sexual assault and two rapes. Overall, the GQM stressed how the interview was mainly conducted in an inappropriate manner. The results are examined with regard to scientific knowledge on young witnesses and victims’ memory. Finally, it is argued that expert witnesses in inquisitorial systems might use the GQM while encountering difficulties to fulfill the legal standards for expert evidence in adversarial systems because of the lack of studies regarding its reliability.
Performance of the predator Amblyseius swirskii (Acari: Phytoseiidae) on greenhouse eggplants in the absence and presence of pine Pinus brutia (Pinales:Pinaceae) pollen
Authors: Kutuk Halil 
Published: February 2017

AbstractIn Turkey, the western thrips Frankliniella occidentalis (Pergande) is a key pest affecting eggplants grown in greenhouses for which an appropriate control strategy is under investigation. It was observed in a previous study that the release of the beneficial predatory mite Amblyseius swirskii (Athias‐Henriot) alone did not result in an effective control of thrips on eggplants. Since pollen is known to improve control efficiency of predators, this study was undertaken to investigate if provision of pollen to eggplants can greatly improve the efficiency of A. swirskii in controlling thrips. The experiments were carried out in both greenhouse and low tunnel. The provision of pollen led to a significant increase in the predator population density on the eggplants but did not result in an effective control of the thrips populations. In this paper, various factors are discussed that could have affected the efficiency of the predatory mite in controlling F. occidentalis on eggplants.
Patients with non‐substance‐related disorders report a similar profile of childhood trauma experiences compared to heroin‐dependent patients
Authors: Schwaninger Philipp V. , Mueller Sandra E. , Dittmann Rebecca , Poespodihardjo Renanto , Vogel Marc , Wiesbeck Gerhard A. , Walter Marc , Petitjean Sylvie A. 
Published: February 2017

Background and ObjectivesExposure to traumatic events is common among patients with substance use disorders (SUD). In patients with non‐substance‐related disorders, especially with gambling disorders (GD) and internet addiction (IA), traumatic childhood experiences have not been investigated extensively. The objective of this study was to compare trauma histories in patients with GD and IA to patients with heroin dependence.MethodsCross‐sectional surveys including the childhood trauma questionnaire (CTQ) and clinical data among 107 participants; 59 patients with non‐substance‐related disorders (GD [n = 39]; IA [n = 20]) were compared to 28 patients prescribed injectable heroin for opioid dependence in heroin‐assisted treatment (HAT) and to a healthy control group (HC) (n = 20).ResultsThe findings revealed a high prevalence of trauma exposure in all three clinical groups, with 74.4% of patients with GD, 80.0% of patients with IA, and 93.0% of patients in HAT compared to 40% in HC. All three groups (GD, IA, HAT) reported significantly higher levels of “emotional neglect” compared to HC.Conclusions and Scientific SignificanceThe results provide clinically relevant information suggesting that the burden of childhood traumatic experiences may be as common in patients with GD and IA as in patients with heroin dependence. These findings could pose an important starting‐point for treatment. (Am J Addict 2017;26:215–220)
Upregulated expression of La ribonucleoprotein domain family member 6 and collagen type I gene following water‐filtered broad‐spectrum near‐infrared irradiation in a 3‐dimensional human epidermal tissue culture model as revealed by microarray analysis
Authors: Tanaka Yohei , Nakayama Jun 
Published: February 2017

AbstractBackground/ObjectivesWater‐filtered broad‐spectrum near‐infrared irradiation can induce various biological effects, as our previous clinical, histological, and biochemical investigations have shown. However, few studies that examined the changes thus induced in gene expression. The aim was to investigate the changes in gene expression in a 3‐dimensional reconstructed epidermal tissue culture exposed to water‐filtered broad‐spectrum near‐infrared irradiation.MethodsDNA microarray and quantitative real‐time polymerase chain reaction (PCR) analysis was used to assess gene expression levels in a 3‐dimensional reconstructed epidermal model composed of normal human epidermal cells exposed to water‐filtered broad‐spectrum near‐infrared irradiation. The water filter allowed 1000–1800 nm wavelengths and excluded 1400–1500 nm wavelengths, and cells were exposed to 5 or 10 rounds of near‐infrared irradiation at 10 J/cm2.ResultsA DNA microarray with over 50 000 different probes showed 18 genes that were upregulated or downregulated by at least twofold after irradiation. Quantitative real‐time PCR revealed that, relative to control cells, the gene encoding La ribonucleoprotein domain family member 6 (LARP6), which regulates collagen expression, was significantly and dose‐dependently upregulated (P < 0.05) by water‐filtered broad‐spectrum near‐infrared exposure. Gene encoding transcripts of collagen type I were significantly upregulated compared with controls (P < 0.05).ConclusionsThis study demonstrates the ability of water‐filtered broad‐spectrum near‐infrared irradiation to stimulate the production of type I collagen.
Low‐dose prednisone and immunoglobulin G treatment for woman at risk for neonatal alloimmune thrombocytopenia and T helper 1 immunity
Authors: Skariah Annie , Sung Nayoung , Salazar Garcia Maria D. , Wu Li , Tikoo Anjali , Gilman‐Sachs Alice , Kwak‐Kim Joanne 
Published: February 2017

ProblemFetal and neonatal alloimmune thrombocytopenia is an alloimmune disorder resulting from platelet opsonization by maternal antibodies that destroy fetal platelets. As there is no antenatal screening or immunization to prevent sensitization, selection of high‐risk population or the prevention of antenatal sensitization is significantly limited.Method of study(i) A case report of ante‐ and postnatal management of a woman with paternal homozygosity for human platelet antigen‐1(HPA) incompatibility. (ii) A retrospective case‐control study of 11 confirmed FNAIT patients, 8 possible‐FNAIT women, and 10 women with confirmed ITP.ResultAntenatal screening, prevention of maternal sensitization by serial monitoring and immunosuppression with prednisone and intravenous immunoglobulin G (IVIG) infusion resulted in two successful pregnancies without sensitization.ConclusionScreening for couples at risk and prednisone and/or IVIG treatment is an option for women with paternal homozygosity for offending HPA antigen to prevent antenatal sensitization. HPA incompatibility is associated with increased Th1 immunity and NK cell cytotoxicity.
Vagal nerve stimulation reduces infarct size via a mechanism involving the alpha‐7 nicotinic acetylcholine receptor and downregulation of cardiac and vascular arginase
Authors: Kiss A. , Tratsiakovich Y. , Mahdi A. , Yang J. , Gonon A. T. , Podesser B. K. , Pernow J. 
Published: February 2017

AbstractAimsVagal nerve stimulation (VNS) protects from myocardial and vascular injury following myocardial ischaemia and reperfusion (IR) via a mechanism involving activation of alpha‐7 nicotinic acetylcholine receptor (α7 nAChR) and reduced inflammation. Arginase is involved in development of myocardial IR injury driven by inflammatory mediators. The aim of the study was to clarify whether VNS downregulates myocardial and vascular arginase via a mechanism involving activation of α7 nAChR following myocardial IR.MethodsAnaesthetized rats were randomized to (i) sham‐operated, (ii) control IR (30‐min ischaemia and 2‐h reperfusion, (iii) VNS throughout IR, (iv) the arginase inhibitor nor‐NOHA+IR, (v) nor‐NOHA+VNS+IR, (vi) selective α7 nAChR blockade by methyllycaconitine (MLA) followed by VNS throughout IR and (vii) MLA+IR.ResultsInfarct size was reduced by VNS compared to control IR (41 ± 3% vs. 67 ± 2% of the myocardium at risk, P < 0.001). Myocardial IR increased myocardial and aortic arginase activity 1.7‐ and 3.1‐fold respectively (P < 0.05). VNS attenuated the increase in arginase activity compared to control IR both in the myocardium and aorta (P < 0.05). MLA partially abolished the cardioprotective effect of VNS and completely abrogated the effect of VNS on arginase activity. Arginase inhibition combined with VNS did not further reduce infarct size.ConclusionVagal nerve stimulation reduced infarct size and reversed the upregulation of arginase induced by IR both in the myocardium and aorta via a mechanism depending on α7 nAChR activation. The data suggest that the cardioprotective effect of VNS is mediated via reduction in arginase activity.
Systematic review with meta‐analysis: the efficacy and safety of CT‐P13, a biosimilar of anti‐tumour necrosis factor‐α agent (infliximab), in inflammatory bowel diseases
Authors: Komaki Y. , Yamada A. , Komaki F. , Micic D. , Ido A. , Sakuraba A. 
Published: February 2017

SummaryBackgroundBiosimilars of anti‐tumour necrosis factor (TNF)‐α agents have now become clinically available for the treatment of inflammatory bowel diseases (IBD).AimTo perform a systematic review and meta‐analysis to evaluate the efficacy and safety of biosimilars of anti‐TNF‐α agents in patients with IBD.MethodsElectronic databases were searched. The outcomes were the pooled rates of clinical response or remission, sustained clinical response or remission, and adverse events in patients with IBD induced with or switched to biosimilars of anti‐TNF‐α agents.ResultsEleven observational studies reporting outcomes in 829 patients treated with biosimilar of infliximab (CT‐P13) were identified. The pooled rates of clinical response among Crohn's disease (CD) and ulcerative colitis (UC) at 8–14 weeks were 0.79 (95% confidence interval (CI) = 0.65–0.88) and 0.74 (95% CI = 0.65–0.82), respectively, and at 24–30 weeks were 0.77 (95% CI = 0.63–0.86) and 0.77 (95% CI = 0.67–0.85) respectively. Adverse events were rare (CD, 0.08 (95% CI = 0.02–0.26); UC, 0.08 (95% CI = 0.03–0.17)). The pooled rates of sustained clinical response among CD and UC after switching from infliximab to CT‐P13 at 30–32 weeks were 0.85 (95% CI = 0.71–0.93) and 0.96 (95% CI = 0.58–1.00), respectively, and at 48–63 weeks were 0.75 (95% CI = 0.44–0.92) and 0.83 (95% CI = 0.19–0.99) respectively. Adverse events were rare (CD, 0.10, 95% CI = 0.02–0.31; UC, 0.22, 95% CI = 0.04–0.63).ConclusionsCT‐P13 was associated with excellent clinical efficacy and safety profile, supporting its use in the treatment of IBD.
Intra‐patient variability in adalimumab drug levels within and between cycles in Crohn's disease
Authors: Ward M. G. , Thwaites P. A. , Beswick L. , Hogg J. , Rosella G. , Van Langenberg D. , Reynolds J. , Gibson P. R. , Sparrow M. P. 
Published: February 2017

SummaryBackgroundWhether therapeutic drug monitoring for adalimumab needs to be performed at trough has not been defined.AimTo determine intra‐patient adalimumab drug‐level variation and to identify modulating patient and disease factors.MethodsIn this prospective observational study, adult patients with Crohn's disease established on maintenance adalimumab had drug levels measured repeatedly according to pre‐defined schedules (visit 1: day 4–6, visit 2: day 7–9, trough: day 13–14) across two consecutive fortnightly cycles. Disease activity was assessed using Harvey–Bradshaw Index, C‐reactive protein and faecal calprotectin. For this analysis, trough levels ≥4.9 μg/mL were considered therapeutic.ResultsNineteen patients underwent 111 evaluations. Mean intra‐patient drug levels from paired visits between cycles did not differ (visit1 cycle1: 4.81, cycle2: 5.21 μg/mL, P = 0.24, visit2 cycle1: 4.86, cycle2: 4.82, P = 0.91 and trough cycle1: 3.95, cycle2: 3.95, P = 0.99), irrespective of disease activity. Drug levels were stable over the first 9 days (visit 1–2), but declined to trough by a mean 1.06 and 0.89 μg/mL between visit 1 or 2, respectively (P < 0.001). Models using nontemporal factors (smoking, syringe delivery device) and levels at earlier visits accounted for 66–80% of the variance in trough levels. On receiver‐operating curve analysis, thresholds identified in the first 9 days that predicted a therapeutic trough level were similar to the trough threshold itself, with high sensitivity but modest specificity.ConclusionWhile therapeutic drug monitoring should be performed at trough, a drug level ≥4.9 μg/mL obtained during the first 9 days predicts a therapeutic trough drug level with reasonable confidence.
The potential of volatile organic compounds for the detection of active disease in patients with ulcerative colitis
Authors: Smolinska A. , Bodelier A. G. L. , Dallinga J. W. , Masclee A. A. M. , Jonkers D. M. , van Schooten F.‐J. , Pierik M. J. 
Published: February 2017

SummaryBackgroundTo optimise treatment of ulcerative colitis (UC), patients need repeated assessment of mucosal inflammation. Current non‐invasive biomarkers and clinical activity indices do not accurately reflect disease activity in all patients and cannot discriminate UC from non‐UC colitis. Volatile organic compounds (VOCs) in exhaled air could be predictive of active disease or remission in Crohn's disease.AimTo investigate whether VOCs are able to differentiate between active UC, UC in remission and non‐UC colitis.MethodsUC patients participated in a 1‐year study. Clinical activity index, blood, faecal and breath samples were collected at each out‐patient visit. Patients with clear defined active faecal calprotectin >250 μg/g and inactive disease (Simple Clinical Colitis Activity Index <3, C‐reactive protein <5 mg/L and faecal calprotectin <100 μg/g) were included for cross‐sectional analysis. Non‐UC colitis was confirmed by stool culture or radiological evaluation. Breath samples were analysed by gas chromatography time‐of‐flight mass spectrometry and kernel‐based method to identify discriminating VOCs.ResultsIn total, 72 UC (132 breath samples; 62 active; 70 remission) and 22 non‐UC‐colitis patients (22 samples) were included. Eleven VOCs predicted active vs. inactive UC in an independent internal validation set with 92% sensitivity and 77% specificity (AUC 0.94). Non‐UC colitis patients could be clearly separated from active and inactive UC patients with principal component analysis.ConclusionsVolatile organic compounds can accurately distinguish active disease from remission in UC and profiles in UC are clearly different from profiles in non‐UC colitis patients. VOCs have demonstrated potential as new non‐invasive biomarker to monitor inflammation in UC.
Long‐term use of oral nucleos(t)ide analogues for chronic hepatitis B does not increase cancer risk – a cohort study of 44 494 subjects
Authors: Wong G. L.‐H. , Tse Y.‐K. , Yip T. C.‐F. , Chan H. L.‐Y. , Tsoi K. K.‐F. , Wong V. W.‐S. 
Published: February 2017

SummaryBackgroundPatients with chronic hepatitis B (CHB) need long‐term antiviral treatment with nucleos(t)ide analogues (NA). Animal studies suggest that some NA may increase cancer risk, but human data are lacking.AimTo investigate cancer risks in patients with or without NA treatment.MethodsWe conducted a territory‐wide cohort study using the database from Hospital Authority in Hong Kong. The diagnosis of CHB and various malignancies was based on the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) diagnosis codes between 2000 and 2012. Patients exposed to any of the oral NA for CHB were included. The primary outcome was incident cancers. A 3‐year landmark analysis, with follow‐up up to 7 years, was used to evaluate the relative risk of cancers in treated and untreated patients.ResultsA total of 44 494 patients (39 712 untreated and 4782 treated) were included in the analysis. During 194 890 patient‐years of follow‐up, hepatocellular carcinoma developed in 402 (1.0%) untreated patients and 179 (3.7%) treated patients, while other cancers developed in 528 (1.3%) and 128 (2.7%) patients respectively. After propensity score weighting, treated patients had similar risks of all malignancies [weighted hazard ratio (wHR): 1.01, 95% CI: 0.82–1.25, P = 0.899], lung/pleural cancers (wHR: 0.82, 95% CI: 0.52–1.31, P = 0.409) and urinary/renal malignancies (wHR: 1.04, 95% CI: 0.38–2.81, P = 0.944) when compared with untreated patients.ConclusionsOral nucleos(t)ide analogue treatment does not appear to increase cancer risk in patients with chronic hepatitis B. Given the beneficial effect on liver outcomes, our data support the current practice of long‐term anti‐viral therapy.