bluuebunny/crossref_metadata_2025_split huggingface dataset:
Les médecins de famille et la santé mentale : une expertise en mal de reconnaissance ou une pratique différente de celle des psychiatres ?
Authors: Karazivan Philippe , Leclaire Marie , Andres Cédric 
Published: June 2017

Le système de santé au Québec a connu, dans la foulée du Plan d’action en santé mentale, des transformations majeures dans les services publics destinés à la santé mentale. Plusieurs patients, autrefois suivis en psychiatrie, se voient désormais orientés et traités en première ligne. Cette réforme fût mise en place alors qu’on connaissait paradoxalement assez peu la pratique et les besoins des omnipraticiens qui prodiguent les soins en santé mentale à une vaste proportion de la population. Les études évaluant leur pratique clinique démontrent une divergence dans l’application des guides de pratique par rapport aux psychiatres et concluent souvent à une compétence moindre sur le plan des compétences diagnostiques. L’objectif de cette étude est de comprendre la nature de la pratique des omnipraticiens en santé mentale, leurs besoins et surtout les limites perçues par eux-mêmes de leurs prises en charge. À l’aide d’une méthodologie qualitative d’analyse de contenu, nous avons analysé 57 demandes de consultation des omnipraticiens envers une équipe spécialisée en santé mentale. Les demandes analysées révèlent certaines particularités de cette pratique : l’incertitude liée au vaste spectre de la normalité, l’aspect longitudinal de la relation et la proximité du soma, et permettent de dégager certains axes autour desquels on peut d’ores et déjà articuler les efforts de collaboration, d’enseignement et d’organisation de soins en santé mentale de première ligne.
O PAPEL DA LÍNGUA PORTUGUESA NA COMPOSIÇÃO DE UMA ELITE POLÍTICA EM TIMOR-LESTE: SUBSÍDIOS PARA UMA DISCUSSÃO POLÍTICO-LINGUÍSTICA SOBRE LUSOFONIA
Authors: Silveira Alexandre Cohn da 
Published: June 2017

O presente artigo busca discutir a relação entre a língua portuguesa e a formação de uma elite política na República Democrática de Timor-Leste (RDTL), a dos presidentes da república do período democrático. Trata-se de verificar como a língua portuguesa contribui para a constituição dessa elite após a guerrilha de resistência contra a Indonésia, bem como analisar possíveis contribuições que as relações estabelecidas pela língua (também relações de poder) trazem para a produção de um discurso favorável à presença da língua portuguesa no país. Para tanto, são analisadas as biografias oficiais três presidentes timorenses, a partir das quais um debate interdisciplinar é desenvolvido. De um lado, estudiosos da teoria das elites e da sociologia do poder, tais como Bourdieu (1983, 1989, 2015), Saint-Martin (2008), Coradini (2001, 2003), Seidl (2013), Codato (2008), Anjos (2006) e Dallabrida (2001) auxiliam o entendimento quanto à formação, à conversão e à manutenção das elites; e, de outro lado, os estudos das Políticas Linguísticas por Makoni e Meinhof (2006), Mariani (2004) , Shohami (2006) e Rajagopalan (2003), permitem um entendimento pontual sobre discursos produzidos sobre a língua. O que se percebe é que a língua portuguesa, tal como aconteceu em outras ex-colônias lusitanas, foi acessada por uma pequena elite local de timorenses que possuíam contato direto com a metrópole e depois, dadas as circunstâncias políticas e de guerra que o país asiático vivenciou, a língua foi discursivizada como artefato político, constituindo um projeto nacionalista lusófono que nem sempre corrobora com as dinâmicas linguísticas do cotidiano.
O PATRIARCALISMO EM “GABRIELA, CRAVO E CANELA”: O ESTILHAÇAR DO RITUAL IDEOLÓGICO RADICAL
Authors: Queiroz Ana Patrícia Cavalcanti 
Published: June 2017

A obra Gabriela, cravo e canelade Jorge Amado tem como cenário a cidade de Ilhéus, em 1925, quando o patriarcalismo tinha força e circulação. Nos propomos a analisar os personagens Malvina, Gabriela e Nacib a fim de traçar seus perfis subversivos e evidenciar como eles romperam com o discurso machista filiado a ideologia patriarcal que era circulado e, consequentemente, preservado na conjuntura Coronelista, na qual a mulher era marginalizada. Além disso, pretende-se relacionar a subversão desses personagens com o processo de desidentificação abordado por Pêcheux (1995). A partir de conceitos da Análise de Discurso (doravante AD), evidenciamos tanto a desidentificação de Malvina, Gabriela e Nacib quanto a dos cidadãos(-sujeitos) de Ilhéus no que concerne à ideologia e ao discurso vigente da época.
Serum N‐glycome alterations in breast cancer during multimodal treatment and follow‐up
Authors: Saldova Radka , Haakensen Vilde D. , Rødland Einar , Walsh Ian , Stöckmann Henning , Engebraaten Olav , Børresen‐Dale Anne‐Lise , Rudd Pauline M. 
Published: June 2017

Using our recently developed high‐throughput automated platform, N‐glycans from all serum glycoproteins from patients with breast cancer were analysed at diagnosis, after neoadjuvant chemotherapy, surgery, radiotherapy and up to 3 years after surgery. Surprisingly, alterations in the serum N‐glycome after chemotherapy were pro‐inflammatory with an increase in glycan structures associated with cancer. Surgery, on the other hand, induced anti‐inflammatory changes in the serum N‐glycome, towards a noncancerous phenotype. At the time of first follow‐up, glycosylation in patients with affected lymph nodes changed towards a malignant phenotype. C‐reactive protein showed a different pattern, increasing after first line of neoadjuvant chemotherapy, then decreasing throughout treatment until 1 year after surgery. This may reflect a switch from acute to chronic inflammation, where chronic inflammation is reflected in the serum after the acute phase response subsides. In conclusion, we here present the first time‐course serum N‐glycome profiling of patients with breast cancer during and after treatment. We identify significant glycosylation changes with chemotherapy, surgery and follow‐up, reflecting the host response to therapy and tumour removal.
Connections matter: Updraft merging in organized tropical deep convection
Authors: Glenn I. B. , Krueger Steven K. 
Published: June 2017

AbstractWhen tropical cumulus convection is organized, the spacing between updrafts is reduced, and deep convective cloud tops are higher. The relative importance of various processes through which organization increases cloud top heights is not well understood. It is likely that decreased spacing between updrafts in organized convection increases the frequency of convective updraft merging. What is the relative importance of merging in determining an updraft parcel's detrainment height? We investigated updraft parcel merging in organized deep convection using results from a large eddy simulation. We used Lagrangian parcel trajectories (LPTs) to locate merging events. LPTs that merge reach detrainment heights 1.5 km higher on average than LPTs which do not merge. Merged LPTs are more buoyant than nonmerged LPTs, implying less dilution due to entrainment. Using mutual information analysis, we found that merging, cloud base vertical velocity, and cloud base area are about equally important in determining parcel detrainment height.
New particle formation from sulfuric acid and amines: Comparison of monomethylamine, dimethylamine, and trimethylamine
Authors: Olenius Tinja , Halonen Roope , Kurtén Theo , Henschel Henning , Kupiainen‐Määttä Oona , Ortega Ismael K. , Jen Coty N. , Vehkamäki Hanna , Riipinen Ilona 
Published: June 2017

AbstractAmines are bases that originate from both anthropogenic and natural sources, and they are recognized as candidates to participate in atmospheric aerosol particle formation together with sulfuric acid. Monomethylamine, dimethylamine, and trimethylamine (MMA, DMA, and TMA, respectively) have been shown to enhance sulfuric acid‐driven particle formation more efficiently than ammonia, but both theory and laboratory experiments suggest that there are differences in their enhancing potentials. However, as quantitative concentrations and thermochemical properties of different amines remain relatively uncertain, and also for computational reasons, the compounds have been treated as a single surrogate amine species in large‐scale modeling studies. In this work, the differences and similarities of MMA, DMA, and TMA are studied by simulations of molecular cluster formation from sulfuric acid, water, and each of the three amines. Quantum chemistry‐based cluster evaporation rate constants are applied in a cluster population dynamics model to yield cluster concentrations and formation rates at boundary layer conditions. While there are differences, for instance, in the clustering mechanisms and cluster hygroscopicity for the three amines, DMA and TMA can be approximated as a lumped species. Formation of nanometer‐sized particles and its dependence on ambient conditions is roughly similar for these two: both efficiently form clusters with sulfuric acid, and cluster formation is rather insensitive to changes in temperature and relative humidity. Particle formation from sulfuric acid and MMA is weaker and significantly more sensitive to ambient conditions. Therefore, merging MMA together with DMA and TMA introduces inaccuracies in sulfuric acid‐amine particle formation schemes.
A novel approach to evaluate soil heat flux calculation: An analytical review of nine methods
Authors: Gao Zhongming , Russell Eric S. , Missik Justine E. C. , Huang Maoyi , Chen Xingyuan , Strickland Chris E. , Clayton Ray , Arntzen Evan , Ma Yulong , Liu Heping 
Published: June 2017

AbstractThere are no direct methods to evaluate calculated soil heat flux (SHF) at the surface (G0). Instead, validation and cross evaluation of methods for calculating G0 usually rely on the conventional calorimetric method or the degree of the surface energy balance closure. However, there is uncertainty in the calorimetric method itself, and factors apart from G0 also contribute to nonclosure of the surface energy balance. Here we used a novel approach to evaluate nine different methods for calculating SHF, including the calorimetric method and methods based on analytical solutions of the heat diffusion equation. The SHF (Gz) measured by a self‐calibrating SHF plate at a depth of z = 5 cm below the surface (hereafter Gm_5cm) was deployed as a reference. Each SHF calculation method was assessed by comparing the calculated Gz at the same depth (hereafter Gc_5cm) with Gm_5cm. The calorimetric method and simple measurement method performed best in determining Gc_5cm but still underestimated Gm_5cm by 19% during the daytime. Possible causes for this underestimation include errors and uncertainties in SHF measurements and soil thermal properties, as well as the phase lag between Gc_5cm and Gm_5cm. Our results indicate that the calorimetric method achieves the most accurate SHF estimates if self‐calibrating SHF plates are deployed at two depths (e.g., 5 cm and 10 cm), soil temperature and water content measurements are made in a few depths between the two plates, and soil thermal properties are accurately quantified.
Geochemistry of the Bagnold dune field as observed by ChemCam and comparison with other aeolian deposits at Gale Crater
Authors: Cousin Agnes , Dehouck Erwin , Meslin Pierre‐Yves , Forni Olivier , Williams Amy J. , Stein Nathan , Gasnault Olivier , Bridges Nathan , Ehlmann Bethany , Schröder Susanne , Payré Valérie , Rapin William , Pinet Patrick , Sautter Violaine , Lanza Nina , Lasue Jérémie , Maurice Sylvestre , Wiens Roger C. 
Published: June 2017

AbstractThe Curiosity rover conducted the first field investigation of an active extraterrestrial dune. This study of the Bagnold dunes focuses on the ChemCam chemical results and also presents findings on the grain size distributions based on the ChemCam Remote Micro‐Imager and Mars Hand Lens Imager images. These active dunes are composed of grains that are mostly <250 μm. Their composition is overall similar to that of the aeolian deposits analyzed all along the traverse (“Aeolis Palus soils”). Nevertheless, the dunes contain less volatiles (Cl, H, and S) than the Aeolis Palus soils, which appear to be due to a lower content of volatile‐rich fine‐grained particles (<100 μm) or a lower content of volatile‐rich amorphous component, possibly as a result of (1) a lower level of chemical alteration, (2) the removal of an alteration rind at the surface of the grains during transport, (3) a lower degree of interaction with volcanic gases/aerosols, or (4) physical sorting that removed the smallest and most altered grains. Analyses of the >150 μm grain‐size dump piles have shown that coarser grains (150–250 μm) are enriched in the mafic elements Fe and Mn, suggesting a larger content in olivine compared to smaller grains (<150 μm) of the Bagnold dunes. Moreover, the chemistry of soils analyzed in the vicinity of the dunes indicates that they are similar to the dune material. All these observations suggest that the olivine content determined by X‐ray diffraction of the <150 μm grain‐size sample should be considered as a lower limit for the Bagnold dunes.
Development
Authors: Kiely Ray 
Published: June 2017

Abstract
The relationship between globalization and development is a problematic one, not only in the real world, but also because there is a lack of clarity over both terms in the debate. For example, the study of development rose to prominence in the period after 1945, but classical political economy's focus on the wealth of nations had been effectively concerned with development. In the postwar period, development was something which largely focused on the nation‐state, but it was also a global phenomenon, much of which was concerned, as we will see, with whether the global context hindered or boosted developmental prospects. Most of the debate, however, is concerned with the relationship between the globalization of the past 30 years, and developmental prospects for poorer countries. But even this is complicated by the fact that there are different meanings of development, particularly as in recent years some critical thinkers have questioned the idea that development is desirable (Escobar 1995). The bulk of this entry will focus on the relationship between globalization and development in recent years, but to do this, some consideration of the postwar period is also needed. There are therefore three sections: the first examines development in the postwar period up until the neoliberal turn in the late 1970s and early 1980s; second, the question of globalization is briefly examined, and related to the development debate and, specifically, renewed modernization theory; and third, the relationship between contemporary globalization and development is examined in some depth, in part through a defense of the debates over development theory that are too often regarded as being out of date in the global era.
Chemotaxonomy in Relation to Molecular Phylogeny of Plants
Authors: Wink Michael , Waterman Peter G. 
Published: June 2017

AbstractThe sections in this article areIntroductionThe Establishment of Chemotaxonomy as a Research DisciplineDevelopments in Small Molecule Chemotaxonomy Over the Past 25 YearsMolecular Biology and Plant TaxonomyComparison between Patterns of Secondary Metabolites and Molecular PhylogenyAcknowledgements
Spatial and Temporal Variation in Vacuolar Contents
Authors: Tomos A.D. , Leigh R.A. , Koroleva O.A. 
Published: June 2017

AbstractThe sections in this article areIntroductionFunctional Roles of VacuolesGeneric Factors Affecting Vacuolar Solute CompositionEvidence for Heterogeneous Distribution of SolutesStorage of WaterConclusions
Vacuolar Transport of Secondary Metabolites and Xenobiotics
Authors: Martinoia E. , Klein M. , Geisler M. , Sánchez‐Fernández R. , Rea P.A. 
Published: June 2017

AbstractThe sections in this article areIntroductionCommon Pathways for DetoxificationSecondary Energized Transporters andABCTransportersCharacteristics of VacuolarABCTransportersConclusions and OutlookNoteAcknowledgments
Protein–Protein Interactions in Plant Thioredoxin Dependent Systems
Authors: Meyer Yves , Miginiac‐Maslow Myroslawa , Schürmann Peter , Jacquot Jean‐Pierre 
Published: June 2017

AbstractThe sections in this article areIntroductionDescription of the Chloroplastic and Cytosolic Systems in Eukaryotic PlantsMechanism of Thioredoxin Catalysis and ConsequencesMolecular Properties of the Thioredoxin Dependent Enzymes and Protein–Protein Recognition PropertiesNew Approaches for the Characterization of Thioredoxin TargetsConclusions
Protein–Protein Interactions in the Regulation of Plant Gene Transcription
Authors: Zhou Dao‐Xiu 
Published: June 2017

AbstractThe sections in this article areIntroductionPlantDNA‐Binding Transcription FactorsCombinatory Interactions and the Regulation of Specific Gene ExpressionInteraction with Signaling ProteinsExtensive Protein Interactions Leading to the Assembly of Transcriptional Initiation ComplexesConclusions
The Composition and Structure of Plant Primary Cell Walls
Authors: O'Neill Malcolm A. , York William S. 
Published: June 2017

AbstractThe sections in this article areIntroductionDefinition of the WallThe Composition of the Primary Cell WallThe Macromolecular Components of Primary WallsDetermination of the Structures of Primary Wall PolysaccharidesOligosaccharide Profiling of Cell Wall PolysaccharidesThe Structures of the Polysaccharide Components of Primary WallsThe Pectic PolysaccharidesOther Primary Wall ComponentsGeneral Features of Wall Ultrastructural ModelsConclusionsAcknowledgements
Non‐Enzymic Cell Wall (glyco)Proteins
Authors: Johnson Kim L. , Jones Brian J. , Schultz Carolyn J. , Bacic Antony 
Published: June 2017

AbstractThe sections in this article areIntroductionHydroxyproline‐Rich Glycoproteins (HRGPs)Glycine‐Rich Proteins (GRPs)Other Wall ProteinsConclusionAcknowledgements
‘Omics’ Approaches Towards Understanding Plant Phosphorus Acquisition and Use
Authors: Lan Ping , Li Wenfeng , Schmidt Wolfgang 
Published: June 2017

Abstract

Low availability of inorganic phosphate (Pi) induces dramatic changes in developmental and metabolic programs as well as in transcriptomic, proteomic and metabolomics profiles. Technical advances in ‘bottom‐up’ omics technologies have allowed novel and integrative insights into acclimative responses of plants, most of which are readily applicable to the development of Pi‐efficient crops. In this chapter, recent omics‐based progress in the genome‐wide analysis of transcriptional and post‐transcriptional gene regulation, Pi starvation‐induced histone modifications, and metabolic alterations that lead to remodelling of membrane lipids and rerouting of the carbohydrate flux is reviewed. Inferred from publicly available data sets, suites are further defined of commonly identified Pi‐responsive genes and proteins as core Pi starvation‐inducible (PSI) genes (the ‘phosphatome’) and proteins in the model species
Arabidopsis thaliana
.
Impacts of lung and tumor volumes on lung dosimetry for nonsmall cell lung cancer
Authors: Lei Weijie , Jia Jing , Cao Ruifen , Song Jing , Hu Liqin 
Published: June 2017

AbstractThe purpose of this study was to determine the impacts of lung and tumor volumes on normal lung dosimetry in three‐dimensional conformal radiotherapy (3DCRT), step‐and‐shoot intensity‐modulated radiotherapy (ssIMRT), and single full‐arc volumetric‐modulated arc therapy (VMAT) in treatment of nonsmall cell lung cancers (NSCLC). All plans were designed to deliver a total dose of 66 Gy in 33 fractions to PTV for the 32 NSCLC patients with various total (bilateral) lung volumes, planning target volumes (PTVs), and PTV locations. The ratio of the lung volume (total lung volume excluding the PTV volume) to the PTV volume (LTR) was evaluated to represent the impacts in three steps. (a) The least squares method was used to fit mean lung doses (MLDs) to PTVs or LTRs with power‐law function in the population cohort (N = 32). (b) The population cohort was divided into three groups by LTRs based on first step and then by PTVs, respectively. The MLDs were compared among the three techniques in each LTR group (LG) and each PTV group (PG). (c) The power‐law correlation was tested by using the adaptive radiation therapy (ART) planning data of individual patients in the individual cohort (N = 4). Different curves of power‐law function with high R2 values were observed between averaged LTRs and averaged MLDs for 3DCRT, ssIMRT, and VMAT, respectively. In the individual cohort, high R2 values of fitting curves were also observed in individual patients in ART, although the trend was highly patient‐specific. There was a more obvious correlation between LTR and MLD than that between PTV and MLD.
Alloy‐Based Anode Materials toward Advanced Sodium‐Ion Batteries
Authors: Lao Mengmeng , Zhang Yu , Luo Wenbin , Yan Qingyu , Sun Wenping , Dou Shi Xue 
Published: June 2017

AbstractSodium‐ion batteries (SIBs) are considered as promising alternatives to lithium‐ion batteries owing to the abundant sodium resources. However, the limited energy density, moderate cycling life, and immature manufacture technology of SIBs are the major challenges hindering their practical application. Recently, numerous efforts are devoted to developing novel electrode materials with high specific capacities and long durability. In comparison with carbonaceous materials (e.g., hard carbon), partial Group IVA and VA elements, such as Sn, Sb, and P, possess high theoretical specific capacities for sodium storage based on the alloying reaction mechanism, demonstrating great potential for high‐energy SIBs. In this review, the recent research progress of alloy‐type anodes and their compounds for sodium storage is summarized. Specific efforts to enhance the electrochemical performance of the alloy‐based anode materials are discussed, and the challenges and perspectives regarding these anode materials are proposed.
Alternatives to Phosphinooxazoline (t‐BuPHOX) Ligands in the Metal‐Catalyzed Hydrogenation of Minimally Functionalized Olefins and Cyclic β‐Enamides
Authors: Biosca Maria , Magre Marc , Coll Mercè , Pàmies Oscar , Diéguez Montserrat 
Published: June 2017

AbstractThis study presents a new series of readily accessible iridium‐ and rhodium‐phosphite/oxazoline catalytic systems that can efficiently hydrogenate, for the first time, both minimally functionalized olefins and functionalized olefins (62 examples in total) in high enantioselectivities (ees up to >99%) and conversions. The phosphite‐oxazoline ligands, which are readily available in only two synthetic steps, are derived from previous privileged 4‐alkyl‐2‐[2‐(diphenylphosphino)phenyl]‐2‐oxazoline (PHOX) ligands by replacing the phosphine moiety by a biaryl phosphite group and/or the introduction of a methylene spacer between the oxazoline and the phenyl ring. The modular design of the ligands has given us the opportunity not only to overcome the limitations of the iridium‐PHOX catalytic systems in the hydrogenation of minimally functionalized Z‐olefins and 1,1‐disubstituted olefins, but also to expand their use to unfunctionalized olefins containing other challenging scaffolds (e.g., exocyclic benzofused and triaryl‐substituted olefins) and also to olefins with poorly coordinative groups (e.g., α,β‐unsaturated lactams, lactones, alkenylboronic esters, etc.) with enantioselectivities typically >95% ee. Moreover, both enantiomers of the hydrogenation product could be obtained by simply changing the configuration of the biaryl phosphite moiety. Remarkably, the new catalytic systems also provided excellent enantioselectivities (up to 99% ee) in the asymmetric hydrogenation of another challenging class of olefins – the functionalized cyclic β‐enamides. Again, both enantiomers of the reduced amides could be obtained by changing the metal from Ir to Rh. We also demonstrated that environmentally friendly propylene carbonate can be used with no loss of enantioselectivity. Another advantage of the new ligands over the PHOX ligands is that the best ligands are derived from the affordable (S)‐phenylglycinol rather than from the expensive (S)‐tert‐leucinol.magnified image