bluuebunny/crossref_metadata_2025_split huggingface dataset:
“You gotta respect”: Mexican-origin Adolescents’ Perspectives on Respect in Organized Activities
Authors: Ettekal Andrea Vest , Gaskin Erin R. , Lin Alex R. , Simpkins Sandra D. 
Published: November 2016

Respect is crucial for promoting participation and positive experiences in organized activities, especially among ethnically diverse youth. However, little is known regarding how Mexican-origin adolescents conceptualize respect and specifically how to promote respect in activities. Guided by theory and previous research, we used qualitative content analysis to elucidate perspectives on respect and features involved in the development of respect in activities. Our sample consisted of 18 Mexican-origin 7th graders who resided in the Southwest of the U.S., an area with a history of inter-ethnic group tensions. The adolescents in this study described three different types of respect: humanity respect, respect for culture, and linguistic respect. Potential features involved in the development of respect were identified, including individual- (e.g., moral virtues), contextual (e.g., welcoming atmosphere), and inter-personal (e.g., shared experiences) features. This study increases out depth of understanding of respect in activities, identifies areas for researchers to pursue in future research, and unveils potential implications for designing activities that promote positive, respectful relationships.
Assessment of Hospital Staff’s Knowledge of Osteopathic Manipulative Medicine: A Survey-Based Study
Authors: Smith-Kelly Jessica B. , Cardenas Andres 
Published: November 2016

Abstract

Context: Research has shown that osteopathic manipulative treatment (OMT) in hospitalized patients can shorten hospital length of stay. However, hospital staff may be unfamiliar with OMT and its use in this setting.

Objective: To assess a hospital staff’s knowledge of osteopathic manipulative medicine (OMM) and investigate whether there is a correlation between job category and knowledge of OMM.

Methods: The study used a 13-item survey that was developed using SurveyMonkey. A brief description stating the purpose of the survey with a hyperlink to the survey was sent in an e-mail to the employee LISTSERV at Good Samaritan Regional Medical Center. This LISTSERV included all 1933 employees at the medical center. After 10 days the survey was closed and the responses were collected and interpreted by a statistician and the primary investigator. Incomplete surveys were included.

Results: A total of 474 employees (24.5%) returned the survey. Of these respondents, 267 (66.9%) responded that OMM could be done in the hospital. Only 97 respondents (24.6%) reported seeing OMM performed in the hospital. Physicians had the highest awareness of OMM (53.7%), compared with all other employees (7%).

Conclusion: An overall lack of knowledge exists regarding OMM among hospital staff, especially nonphysician employees, at a medical clinic.
Effectiveness of Shared Medical Appointments Targeting the Triple Aim Among Patients With Overweight, Obesity, or Diabetes
Authors: Trickett Kristi H. , Matiaco Paul M. , Jones Kathryn , Howlett Bernadette , Early Kathaleen Briggs 
Published: November 2016

AbstractBackground:Obesity and diabetes are epidemic in the United States, with many treatment options having limited long-term efficacy. A possible effective medical management tool is the shared medical appointment (SMA), which offers an efficient and cost-effective approach to behavior change and aligns with the Triple Aim (reduce costs, improve population health, and improve patient care experience) set forth by the Institute for Healthcare Improvement.Objectives:To assess the effectiveness of SMAs to achieve the Triple Aim and to improve the management of overweight/obesity or diabetes.Methods:Peer-reviewed literature from PubMed was searched by the keywordsshared medical appointments,group medical appointment, andgroup medical visit, with no date restrictions and limited to English publications with sample sizes greater than or equal to 20.Results:Eight articles met inclusion criteria. The Triple Aim was not referenced in the studies, but most reported some combination of reduced costs, improved care, and improved outcomes or patient satisfaction.Conclusions:Potential benefits of SMAs include improved patient outcomes and satisfaction. Osteopathic and, in particular, primary care medicine could likely benefit from moving toward greater adoption of SMAs; however, more randomized controlled trials are needed to assess their effectiveness with regard to the Triple Aim.
High speed fabrication of absorbance-enhanced micro–nanostructures on nickel surface using hundred-nanosecond pulsed laser
Authors: Fu Jinxiang , Zhang Jingyuan , Liang Hao , Wang Yibo , Zhang Zhiyan , Liu Yannan , Lin Xuechun 
Published: November 2016

Abstract
We report the generation of micro–nanostructures on nickel surface using a pulsed laser with pulse duration of 100/200 ns. The blacken nickel, which is covered with dense broccoli-like clusters having strong light trapping capacity covering broad spectrum (200–2000 nm), can be produced at a high laser scanning speed up to 100 mm/s. The absorbance of the blacken nickel can be over 98% in the UV, more than 97% in the visible, and over 90% in the near IR. In addition, by treating the nickel surface with two crossing scans of the laser, highly organized and shape-controllable periodic arrays of hump-craters can be fabricated.
Single crystalline growth of a soluble organic semiconductor in a parallel aligned liquid crystal solvent using rubbing-treated polyimide films
Authors: Matsuzaki Tomoya , Shibata Yosei , Takeda Risa , Ishinabe Takahiro , Fujikake Hideo 
Published: November 2016

Abstract
For directional control of organic single crystals, we propose a crystal growth method using liquid crystal as the solvent. In this study, we examined the formation of 2,7-dioctyl[1]benzothieno[3,2-b][1]benzothiophene (C8-BTBT) single crystals using a parallel aligned liquid crystal (LC) cell and rubbing-treated polyimide films in order to clarify the effects of LC alignment on anisotropic C8-BTBT crystal growth. Based on the results, we found that the crystal growth direction of C8-BTBT single crystals was related to the direction of the aligned LC molecules because of rubbing treatment. Moreover, by optical evaluation, we found that the C8-BTBT single crystals have a aligned molecular structure.
Efficient separation of semiconducting single-wall carbon nanotubes by surfactant-composition gradient in gel filtration
Authors: Thendie Boanerges , Omachi Haruka , Miyata Yasumitsu , Shinohara Hisanori 
Published: November 2016

Abstract
Gel filtration is a powerful method of separating and purifying semiconducting single-wall carbon nanotubes (s-SWCNTs) from their metallic (m-) counterpart. However, a small amount of m-SWCNTs usually remains, thus reducing the purity of the s-SWCNTs obtained. We have investigated the effect of elution with a gradient concentration of the surfactant on the separation and purity of s-SWCNTs. By utilizing the controlled low-gradient elution (CLGE) that we have developed, the purity of s-SWCNTs is improved to 94% from the 90% obtained with the conventional separation. Furthermore, CLGE simultaneously allows diameter-based separation of small-diameter s-SWCNTs, which indicates a promising utilization of CLGE for s-SWCNT separation.
Two centuries of nitrogen dynamics: Legacy sources and sinks in the Mississippi and Susquehanna River Basins
Authors: Van Meter K. J. , Basu N. B. , Van Cappellen P. 
Published: December 2016

AbstractGlobal flows of reactive nitrogen (N) have increased significantly over the last century in response to agricultural intensification and elevated levels of atmospheric deposition. Despite widespread implementation conservation measures, N concentrations in surface waters are often remaining steady or continuing to increase. Although such lack of response has been attributed to time lags associated with legacy N stores in subsurface reservoirs, it is unclear what the magnitudes of such stores are and how they are partitioned between shallow soil and deeper groundwater reservoirs. Here we have synthesized data to develop a 214 year (1800–2014) trajectory of N inputs to the land surface of the continental U.S. We have concurrently developed a parsimonious, process‐based model, Exploration of Long‐tErM Nutrient Trajectories (ELEMeNT) that pairs this input trajectory with a travel time‐based approach to simulate transport and retention along subsurface pathways. Using the model, we have reconstructed historic nitrate yields at the outlets of two major U.S. watersheds, the Mississippi River Basin (MRB) and Susquehanna River Basin (SRB). Our results show significant N loading above baseline levels in both watersheds before the widespread use of commercial N fertilizers, largely due to the conversion of forest and grassland to row crop agriculture. Model results also allow us to quantify the magnitudes of legacy N in soil and groundwater pools and to highlight the dominance of soil legacies in MRB and groundwater legacies in SRB. Approximately 55% and 18% of the current annual N loads in the MRB and SRB were found to be older than 10 years of age.
A case of tetanus treated with Kampo medicines such as Kakkonto and Shakuyakukanzoto
Authors: Nakae Hajime , Saito Yuri , Okuyama Manabu , Igarashi Toshiko 
Published: December 2016

CaseA 74‐year‐old man developed tetanus 3 days after working with cow and poultry manure. Kakkonto and shakuyakukanzoto, traditional Japanese herbal medicines that are effective for the relief of pain primarily related to muscle contraction, were given to control the trismus and painful contracture of the neck. Generalized convulsions were controlled without the use of muscle relaxants.OutcomeAfter 30 days, the patient was discharged from the hospital without any sequelae.ConclusionKakkonto and shakuyakukanzoto may be useful for the control of muscle spasms resulting from generalized tetanus.
Propellane: von chemischen Kuriositäten zu “explosiven” Materialen und Naturstoffen
Authors: Dilmaç Alicia M. , Spuling Eduard , de Meijere Armin , Bräse Stefan 
Published: December 2016

AbstractPropellane bilden eine einzigartige Verbindungsklasse, die derzeit aus deutlich mehr 10 000 Vertretern besteht, die alle zwei mehr oder weniger invertierte tetraedrische Kohlenstoffatome aufweisen, die drei Ringbrücken gemeinsam haben. Die zentrale Einfachbindung zwischen den beiden Brückenköpfen ist in den kleineren Gebilden deutlich geschwächt, was zu ungewöhnlichen Reaktivitäten dieser strukturell interessanten Propeller‐artigen Moleküle führt. Dieser Aufsatz soll die Synthesen solcher Propellane und ihr Auftreten in den Materialwissenschaften, Naturstoffen sowie der medizinischen Chemie hervorheben. Die Umwandlung von [1.1.1]Propellan zu Brückenkopfderivaten von Bicyclo[1.1.1]pentan einschließlich Oligomeren sowie Polymeren mit Bicyclo[1.1.1]penta‐1,3‐diyl‐Wiederholungseinheiten wird besonders herausgestellt. Eine Auswahl von Naturstoffen mit größeren Propellanuntereinheiten wird detailliert diskutiert. Außerdem werden Heteropropellane und anorganische Propellane angesprochen. Der historische Hintergrund wird kurz anhand der grundlegenden Arbeiten von David Ginsburg, Günther Snatzke, Kenneth B. Wiberg, Günter Szeimies und anderen angerissen.
ClimaCon: An Autonomous Energy Efficient Climate Control Solution for Smart Buildings
Authors: Farag Wael A. 
Published: December 2016

AbstractIn modern buildings, climate control is an essential aspect to ensure the utmost comfort for the occupants, even though, this very feature represents 40% ~ 70% of the energy consumption of these buildings. Therefore, using energy efficient climate control systems becomes a crucial requirement of modern smart buildings. In this paper, we propose an autonomous energy‐efficient climate control solution “ClimaCon”. ClimaCon is an external extension to any Heat Ventilation and Air Conditioning (HVAC) system. The main objective of this solution is to achieve the best thermal comfort for individuals in all building zones with the least possible energy consumption. The solution consists of several closed loops to control the HVAC actuators while getting measurements and feedback signals through wireless sensing nodes. These nodes are distributed across pre‐determined locations in the building zones. ClimaCon theory of operation is based on observing the thermal comfort of occupants based on predicted mean vote index, and maintaining it within pre‐specified limits; while allowing the execution of various energy saving profiles. The performance of ClimaCon is evaluated using many test cases and extensive simulation studies. These studies prove the ability of the proposed solution to maintain the thermal comfort of occupants in various zones while implementing different energy saving profiles.
Zirconium(IV)‐Catalyzed Ring Opening of on‐DNA Epoxides in Water
Authors: Fan Lijun , Davie Christopher P. 
Published: December 2016

AbstractDNA‐encoded library technology (ELT) has spurred wide interest in the pharmaceutical industry as a powerful tool for hit and lead generation. In recent years a number of “DNA‐compatible” chemical modifications have been published and used to synthesize vastly diverse screening libraries. Herein we report a newly developed, zirconium tetrakis(dodecyl sulfate) [Zr(DS)4] catalyzed ring‐opening of on‐DNA epoxides in water with amines, including anilines. Subsequent cyclization of the resulting on‐DNA β‐amino alcohols leads to a variety of biologically interesting, nonaromatic heterocycles. Under these conditions, a library of 137 million on‐DNA β‐amino alcohols and their cyclization products was assembled.
Improving the Solubility of Artificial Ligands of Streptavidin to Enable More Practical Reversible Switching of Protein Localization in Cells
Authors: Tachibana Ryo , Terai Takuya , Boncompain Gaelle , Sugiyama Shigeru , Saito Nae , Perez Franck , Urano Yasuteru 
Published: December 2016

AbstractChemical inducers that can control target‐protein localization in living cells are powerful tools to investigate dynamic biological systems. We recently reported the retention using selective hook or “RUSH” system for reversible localization change of proteins of interest by addition/washout of small‐molecule artificial ligands of streptavidin (ALiS). However, the utility of previously developed ALiS was restricted by limited solubility in water. Here, we overcame this problem by X‐ray crystal structure‐guided design of a more soluble ALiS derivative (ALiS‐3), which retains sufficient streptavidin‐binding affinity for use in the RUSH system. The ALiS‐3–streptavidin interaction was characterized in detail. ALiS‐3 is a convenient and effective tool for dynamic control of α‐mannosidase II localization between ER and Golgi in living cells.
Direct C3‐Arylation of 2 H‐Indazole Derivatives with Aryl Bromides by using Low Loading of a Phosphine‐free Palladium Catalyst
Authors: Belkessam Fatma , Aidene Mohand , Soulé Jean‐François , Doucet Henri 
Published: December 2016

AbstractThe palladium‐catalyzed direct arylation of 2 H‐indazoles with aryl bromides for the preparation of 3‐aryl‐2 H‐indazoles was found to proceed in high yields when using only 0.5–0.1 mol % Pd(OAc)2 catalyst and KOAc as inexpensive base. A wide variety of electron‐deficient and electron‐rich aryl bromides and also heteroaryl bromides has been successfully employed. Both electron‐withdrawing and electron‐donating substituents on the 2 H‐indazoles are also tolerated. Moreover, the reaction can be performed in the “green” solvent cyclopentyl methyl ether.
A Ligand‐Free Pt3Cluster Catalyzes the Markovnikov Hydrosilylation of Alkynes with up to 106Turnover Frequencies
Authors: Rivero‐Crespo Miguel A. , Leyva‐Pérez Antonio , Corma Avelino 
Published: December 2016

AbstractThe Pt‐catalyzed hydrosilylation of alkynes is the procedure of choice to obtain vinylsilanes, and is claimed to be the most relevant application of Pt in organic synthesis. More than half a century after its discovery, only β‐vinylsilanes (anti‐Markovnikov addition) are obtained with simple Pt catalysts, whereas α‐vinylsilanes (Markovnikov addition) remain elusive compounds. Here the catalysis of the Markovnikov hydrosilylation of terminal alkynes by Pt3clusters, in parts‐per‐million amounts, to give a wide variety of α‐vinylsilanes in reasonable isolated yields and with turnover frequencies that can reach up to one million per hour is reported. Moreover, these α‐vinylsilanes are reactive in well‐stablished C−C bond‐forming cascade reactions, in which the corresponding β‐isomers are unreactive. Besides its efficiency and synthetic usefulness, this catalytic system is an excellent example of how the atom‐by‐atom aggregation of a catalytic metal leads to a different selectivity for a given reaction
Integrative genomic analysis identifies ancestry‐related expression quantitative trait loci on DNA polymerase β and supports the association of genetic ancestry with survival disparities in head and neck squamous cell carcinoma
Authors: Ramakodi Meganathan P. , Devarajan Karthik , Blackman Elizabeth , Gibbs Denise , Luce Danièle , Deloumeaux Jacqueline , Duflo Suzy , Liu Jeffrey C. , Mehra Ranee , Kulathinal Rob J. , Ragin Camille C. 
Published: December 2016

BACKGROUNDAfrican Americans with head and neck squamous cell carcinoma (HNSCC) have a lower survival rate than whites. This study investigated the functional importance of ancestry‐informative single‐nucleotide polymorphisms (SNPs) in HNSCC and also examined the effect of functionally important genetic elements on racial disparities in HNSCC survival.METHODSAncestry‐informative SNPs, RNA sequencing, methylation, and copy number variation data for 316 oral cavity and laryngeal cancer patients were analyzed across 178 DNA repair genes. The results of expression quantitative trait locus (eQTL) analyses were also replicated with a Gene Expression Omnibus (GEO) data set. The effects of eQTLs on overall survival (OS) and disease‐free survival (DFS) were evaluated.RESULTSFive ancestry‐related SNPs were identified as cis‐eQTLs in the DNA polymerase β (POLB) gene (false discovery rate [FDR] < 0.01). The homozygous/heterozygous genotypes containing the African allele showed higher POLB expression than the homozygous white allele genotype (P < .001). A replication study using a GEO data set validated all 5 eQTLs and also showed a statistically significant difference in POLB expression based on genetic ancestry (P = .002). An association was observed between these eQTLs and OS (P < .037; FDR < 0.0363) as well as DFS (P = .018 to .0629; FDR < 0.079) for oral cavity and laryngeal cancer patients treated with platinum‐based chemotherapy and/or radiotherapy. Genotypes containing the African allele were associated with poor OS/DFS in comparison with homozygous genotypes harboring the white allele.CONCLUSIONSAnalyses show that ancestry‐related alleles could act as eQTLs in HNSCC and support the association of ancestry‐related genetic factors with survival disparities in patients diagnosed with oral cavity and laryngeal cancer. Cancer 2017;123:849–60. © 2016 American Cancer Society.
Understanding Reactivity Patterns in Light‐Induced Nitrile Imine Mediated Tetrazole–Ene Cycloadditions
Authors: Blasco Eva , Sugawara Yuuki , Lederhose Paul , Blinco James P. , Kelterer Anne‐Marie , Barner‐Kowollik Christopher 
Published: December 2016

AbstractA rationale for predicting photochemical tetrazole activation in the popular nitrile imine mediated tetrazole–ene cycloaddition (NITEC) reaction, based on a combined theoretical and experimental study, is reported. DFT calculations of three tetrazole derivatives reveal that the efficiency of intersystem crossing is determined by the chromophore moiety. This species is critical in dictating the reactivity of the tetrazoles towards nitrile imine formation, yet mere inspection of the chromophore moiety's absorptivity is insufficient for predicting the tetrazole's photochemical reactivity.
Palladium(II)‐Catalysed Aminocarbonylation of Terminal Alkynes for the Synthesis of 2‐Ynamides: Addressing the Challenges of Solvents and Gas Mixtures
Authors: Hughes N. Louise , Brown Clare L. , Irwin Andrew A. , Cao Qun , Muldoon Mark J. 
Published: December 2016

Abstract2‐Ynamides can be synthesised through PdII catalysed oxidative carbonylation, utilising low catalyst loadings. A variety of alkynes and amines can be used to afford 2‐ynamides in high yields, whilst overcoming the drawbacks associated with previous oxidative methods, which rely on dangerous solvents and gas mixtures. The use of [NBu4]I allows the utilisation of the industrially recommended solvent ethyl acetate. O2 can be used as the terminal oxidant, and the catalyst can operate under safer conditions with low O2 concentrations.
Model‐based Optimal Sabatier Reactor Design for Power‐to‐Gas Applications
Authors: El Sibai Ali , Rihko Struckmann Liisa K. , Sundmacher Kai 
Published: December 2016

AbstractThe existing infrastructure for natural gas storage and transport made the Sabatier process an attractive step within the power‐to‐gas process chain for intermittent renewable energy storage. A model‐based optimal design for the methanation of carbon dioxide with hydrogen to methane under process‐wide constraints is presented. After inclusion of the downstream units into the analysis, the product methane fulfils the specifications for the natural gas grid. The optimization goal was to maximize the space–time yield by applying the systematic flux‐oriented elementary process function methodology. The optimum temperature and concentration profiles along the reaction coordinate were first determined, after which they were approximated using two reaction configurations: 1) a hydrophilic membrane reactor and 2) a cascade of polytropic reactors with interstage condensation. The results show that an optimized cascade of three polytropic fixed bed reactors (e.g., optimum temperature profile) and two intermediate condensation steps is the best technical approximation for maximizing the space–time yield.