bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intestinal microbiota in children with bronchial asthma
Authors: Sokolova T. S. , Malchuk V. N. , Fedorova O. S. , Kulenich V. V. , Odintsova V. E. , Koshechkin S. I. 
Published: October 2024

Background. Intestinal microbiota is one of the most important factors determining the state of human health, including its influence on the immunological mechanisms regulating the development of allergic diseases in childhood. The role of intestinal microbiota and the gut – lung axis in the development of bronchial asthma (BA) is an important area of research.Aim. To analyze the taxonomic composition of intestinal microbiota in children with BA using 16S rRNA gene sequencing.Materials and methods. The study included patients with BA (n = 50, mean age 10.34 ± 2.99 years) and a group of apparently healthy individuals (n = 49, mean age 10.3 ± 2.8 years). For all patients, medical history was taken, and physical examination and stool test were performed. Patients with BA were assessed for the level of total and specific immunoglobulin (Ig) E and underwent spirometry. The microbiota composition was analyzed by 16S rRNA gene sequencing with subsequent bioinformatic and statistical analysis.Results. Significant differences in the composition of the intestinal microbiota (beta diversity) and a decrease in taxonomic diversity (alpha diversity) were found in patients with BA compared to healthy controls. The intestinal microbiota of patients with BA was characterized by an increase in the abundance of Bacteroides, Parabacteroides, Lachnospira, Roseburia, Akkermansia, Anaerostipes, Sutterella, Odoribacter, Phascolarctobacterium, Butyricimonas, as well as unclassified bacteria from the Rikenellaceae families. The intestinal microbiota of children without BA was characterized by greater abundance of bacteria from Blautia, Bifidobacterium, Dorea, Ruminococcus, Streptococcus, Eubacterium, Acinetobacter, Collinsella, Lactococcus, Catenibacterium genera and unclassified bacteria from the Clostridiaceae and Coriobacteriaceae families. Significant differences in the quantitative abundance of bacteria were revealed depending on the type of sensitization, the level of total IgE, and the value of FEV1.Conclusion. The results obtained indicate the differences in the intestinal microbiota composition in children with BA and healthy children.
Evolution of a buried moat–drift system in the Ewing Terrace uncovering highly dynamic bottom currents at the Argentine margin from the early Oligocene to middle Miocene
Authors: Unland Ellen , Miramontes Elda , Spiess Volkhard , Bozzano Graziella , Kasten Sabine , Schwenk Tilmann 
Published: October 2024

ABSTRACT
The Ewing Terrace is a relatively flat surface formed by the action of bottom currents and part of a contourite depositional system (CDS) at the Argentine continental slope. It is situated in a highly complex oceanographic setting at the Brazil–Malvinas Confluence Zone. Located in water depths of ∼ 1000–1200 m and incised by the Mar del Plata Canyon, the Ewing Terrace is separated into the Northern Ewing Terrace (NET) and the Southern Ewing Terrace (SET). The long-term variations in ocean circulation led to a complex internal architecture of the terrace. As a result, this region represents a unique archive for studying sedimentary features that were eroded, transported, and deposited by along-slope and down-slope processes.
An in-depth data analysis of high-resolution multichannel seismic profiles exhibits a complex sequence of erosional and depositional contouritic features, namely buried moat–drift systems identified in depths of ∼ 370–750 m below the seafloor. They are arranged in migrating sequences and clustered in the early Oligocene to middle Miocene. This pattern is probably attributable to the vertical shift of water masses and to a highly dynamic oceanographic setting with spatial changes influenced by the Brazil–Malvinas Confluence Zone over this particular geological time.
The moat–drift systems reveal significant lateral changes from north to south. In the southern area of the SET the moats are constructional and the associated separated mounded drifts are well developed. In contrast, the northern area exhibits two types of moats, reminiscent of cut-and-fill structures that mirror the significant and rapid changes in bottom-current dynamics.
With these new insights, this study contributes to a better understanding of moat–drift systems and improves the knowledge about past oceanographic dynamics and sediment deposition at the northern Argentine margin.
Environmental impact of conventional manufacturing, green manufacturing initiatives to mitigate the impact and enhancing sustainability
Authors: Jena Madhab Chandra , mishra sarat , moharana himanshu 
Published: October 2024

Abstract

The thesis provides a comprehensive overview of the environmental impacts associated with the lifecycle of products, highlighting the need for sustainable practices and responsible consumption. The study focuses on evaluating the environmental impact of manufacturing processes and exploring the benefits of green manufacturing through a case study conducted at a gravure printing factory. By assessing environmental impacts across various phases of the printing process and proposing green initiatives, the research aims to promote sustainable manufacturing practices within the gravure printing industry. The abstract outlines the different phases of the gravure printing process and their corresponding environmental impacts, ranging from raw material extraction to end-of-life disposal. It also discusses green manufacturing initiatives aimed at mitigating environmental impact throughout the product lifecycle, including sustainable sourcing, energy efficiency, waste reduction, and circular economy principles. Overall, the abstract underscores the importance of integrating green manufacturing practices to achieve environmental stewardship and resource efficiency in industrial operations.
From the Ground Up: Stakeholder Perspectives on Housing Interventions to Reduce Environmentally Mediated Infections
Authors: Acklin Matthias , Graham Jay , Benjamin-Chung Jade 
Published: October 2024

Abstract

Background
Housing conditions are intrinsically linked to human health, with inadequate housing potentially increasing exposure to environmentally mediated pathogens. Housing interventions that aim to improve housing and reduce environmentally mediated infections, such as finished floors and housing upgrades for vector-borne diseases, remain relatively under-explored as health interventions. This study explored facilitators of and barriers to funding, implementing, and scaling up housing improvements as health interventions to reduce environmentally mediated infectious diseases.
Methods
Sixteen key informants (KIs) with direct experience in implementing or working within housing interventions and environmentally mediated infectious diseases in low- and middle-income countries were interviewed using a semi-structured interview format. KIs had diverse backgrounds, including academics researching housing interventions, housing policy advisors, and practitioners implementing housing interventions. A thematic analysis approach was used to identify key themes in interview transcripts, highlighting patterns, commonalities, and variations in participants’ responses.
Results
KIs emphasized the multi-dimensional impacts of housing interventions that are intrinsically linked to Sustainable Development Goals (SDGs), including physical and mental health, as well as environmental, social, and economic dimensions. Moreover, a pronounced shortage of funding and financial systems to address housing interventions was highlighted, alongside the urgent need for more rigorous evidence and cost-benefit analyses. Furthermore, the imperative to raise awareness of the significance of housing and the critical importance of strong collaboration across sectors and stakeholders were stressed. Emphasizing the necessity for project-based and context-specific housing policies, the interviews revealed that contextualizing interventions to their specific setting and fostering community involvement are essential for successful implementation and scale-up.
Conclusions
Housing interventions play a pivotal role in mitigating environmentally mediated diseases. These interventions can complement existing strategies like water, sanitation, and hygiene (WASH) interventions, ensuring comprehensive approaches to healthy housing and sustainable development goals amidst climate change.
Effects on tricuspid regurgitation by different techniques for passing permanent pacemaker leads through the tricuspid valve: a randomized, open-label, superiority clinical trial study protocol
Authors: Hong Jianan , Qiu Zhanyi , Xiao Zhongbo , Ni Xiaobin , Fang Yanling , Wu Shiwan , Xie Yandan , Chen Yequn , Chen Chang , Wu Muli 
Published: October 2024

Abstract

Background
In recent years, lead-induced tricuspid regurgitation (LITR) has attracted increasing attention. At present, there are two commonly used transvalvular ways for pacing lead wires to enter the right ventricle. The first transvalvular approach involves placing the tip of the pacing lead directly through the tricuspid valve into the right ventricle, including ‘Direct-crossing’ and ‘Drop-down’. The second transvalvular approach is to bend the pacing lead so that the reflexed lead body crosses the tricuspid valve and then enters the right ventricle, which is ‘prolapsing’. However, there are no clinical trials to evaluate or compare the effects of the above two different pacing lead transvalvular approaches on tricuspid regurgitation. In this study, we will perform a randomized clinical trial to understand the effect of different transvalvular lead wire transversal techniques on the incidence of tricuspid regurgitation.
Methods
376 subjects with right ventricular single-chamber pacemaker implantation or dual-chamber pacemaker implantation were recruited in the First Affiliated Hospital of Shantou University Medical College. Participants will be randomized into the direct group (‘Direct-crossing’ and ‘Drop-down’) or the bending group (‘Prolapsing’). The primary objective is new tricuspid regurgitation or exacerbation of existing tricuspid regurgitation within 1 year of follow-up.
Discussion
This study aims to verify whether different transvalvular approaches influence the incidence of LITR, and is expected to provide an optimized method for routine pacemaker surgery and improve the long-term prognosis and quality of life of patients.
Trial registration:
Chinese Clinical Trials Registry ChiCTR2100045558. Registered on 19 April 2021.
Effect of Hydrogen Leakage on the Life Cycle Climate Impacts of Hydrogen Supply Chains
Authors: Goita Esther , Beagle Emily A. , Nasta Ansh N. , Wissmiller Derek L. , Ravikumar Arvind , Webber Michael E. 
Published: October 2024

Abstract

Hydrogen is of interest for decarbonizing hard-to-abate sectors because it does not produce carbon dioxide when combusted. However, hydrogen has indirect warming effects. In this work, we conducted a life cycle assessment of electrolysis and steam methane reforming to assess their emissions while considering hydrogen’s indirect warming effects. We find that the primary factors influencing life cycle emissions are the production method and related feedstock emissions, rather than the hydrogen leakage and the indirect warming potential of hydrogen. A comparison between fossil fuel-based and hydrogen-based steel production and heavy-duty transportation showed a reduction in greenhouse gas emissions, of approximately 800 to more than 1400 kgCO2e per tonne of steel and 0.1 to 0.17 kgCO2e per tonne-km of cargo. While any hydrogen production pathway reduces greenhouse gas emissions for steel, this is not the case for heavy-duty transportation. Therefore, we recommend a nuanced approach in choosing application areas for hydrogen.
Lavender-Neroli Oil as an Aromatherapy in Children’s Dental Anxiety Reduction during Anesthesia Injection – A Two-Arm Randomized control trial
Authors: Abdalhai Rama , Tolibah Yasser Alsayed , Alkhatib Racha , Kouchaji Chaza 
Published: October 2024

Abstract

This study aimed to assess the effect of aromatherapy with lavender-neroli oil in managing dental anxiety in children. The sample consisted of 54 children aged between 6–11 years who needed an inferior alveolar nerve block anesthesia injection (IANB) for various treatments in mandibular teeth and then they randomly divided into 2 groups: control groups, and aromatherapy group who asked to inhale the aroma of lavender-neroli oil through a nitrous oxide mask for 5 minutes before anesthesia and during IANB injection. The assessment was made before and after anesthesia using a subjective scale (Facial Image Scale (FIS)), objective pain scale (Face-Legs-Activity-Cry-Consolability (FLACC), and changes in physiological parameters using vital signs (Heart rate-blood pressure-SPO2 saturation). There was a significant reduction in anxiety and pain related to IANB anesthesia injection in the aromatherapy group compared to the control group (P < 0.05), a significantly lower level of blood pressure, and heart rate in the aromatherapy group compared to the control group (P < 0.05), and no change was found for O2 saturation. Aromatherapy with lavender-neroli oil is an effective- simple- low-cost way to manage pediatric dental anxiety and pain during IANB injection.
What is the correlation between thickness and anterior posterior width of masseter muscle in ultrasonography with intermolar width in maxilla and mandible?
Authors: Ahsaie Mitra Ghazizadeh , Safi Yaser , Behnaz Mohammad , Valizadeh Solmaz , Arianezhad S. Marjan , Moosavi Zakaria , Ranji Paniz , Dezfouli Negin Kouchak 
Published: October 2024

Abstract

Background
Knowledge of masseter muscle size can be helpful in choosing more successful and stable orthodontic treatment plans. This study aimed to evaluate masseter muscle width and thickness in ultrasonography (USG) and its correlation with dental arch width.
Methods
In this descriptive-cross-sectional study, 45 participants (25 male (55.5%), and 20 female (45.5%)) were categorized according to their sex and age groups (16–20, 21–25, 26–30 Y.O.). The thickness and anterior-posterior width of the masseter muscle in the rest and clenched states were measured bilaterally using USG with the 7.5 MHz linear probe. Inter-molar width was measured using a metal caliper on dental casts of both jaws. The student t-test analysis was used to compare the means between males and females. The relationship between the width and thickness of masseter muscle and intermolar width was evaluated using Spearman correlation coefficient and Pearson correlation coefficient.
Results
Males exhibited significantly thicker and wider masseter muscles in rest and clenched states (P < 0.001). They also had wider dental arches in upper and lower jaws (P < 0.001). Intermolar width correlated significantly with muscle dimensions in both states (P < 0.05). However, age and sex categorization revealed no significant correlations between muscle parameters and intermolar widths (P > 0.05).
Conclusion
USG can be used to measure muscle thickness as a safe and reproducible method. There is a positive correlation between the masseter muscle width and thickness and intermolar width.
Effect of phosphorus content on the microstructure evolution of highly undercooled Al-60%Si alloys
Authors: Dang Bo , Jian Zengyun , Xu Junfeng 
Published: October 2024

Abstract

In order to investigate the effect of P content on the growth morphology and the growth mode of Si phase, the Al-60%Si alloys with 0.5%P and 1.0%P was subjected to deep undercooling by electromagnetic levitator. The morphology evolution and growth mode of Si phase was studied by analyzing the dynamic images recorded by HSV and the SEM images of as-solidified samples. The results reveal that the morphology of Si phase changed from the large strip shape to coarse bulks and regularly arranged dendrites, then to spheroidal and rod-shaped with increasing of undercooling, and the corresponding growth mode changed from lateral growth to mixed growth, then to continuous growth. The P refines the size of the Si phase by increasing the nucleation rate of Si phase. With rising of P content, the critical undercoolings of growth mode transition decrease, and the experimental results well match the theoretical predicted results.
Predictors of neuropsychiatric manifestations in pediatric patients with lupus
Authors: Jiang Wei , Peng Xin , Dong Liqun , Wu Ling , Liu Qiao , Di Yazhen , Lin Li 
Published: October 2024

Abstract

Early detection of neuropsychiatric systemic lupus erythematosus (NPSLE) in children remains a challenge. Previous studies have found an association between different autoantibodies and the occurrence of NPSLE. This study aimed to describe the autoantibodies, organ disorders, SLEDAI-2K score, and complement levels at diagnosis in systemic lupus erythematosus (SLE) and to investigate the predictors of NPSLE. We reviewed medical records and extracted information on the clinical features, serum autoantibodies, and laboratory test results of hospitalized children with SLE (< 18 years old). Multivariable logistic regression was used to determine the predictors of NPSLE and SLE without neuropsychiatric manifestations. The 22.8% children with NPSLE had higher ANA levels and SLEDAI-2K scores, lower C4 levels, and greater AMA-M2, β2GPI Abs, Anti-Rib-P Ab, ANCA, and LAC positivity at SLE diagnosis. They were also more likely to have fever and more easily developed digestive system complications, macrophage activation syndrome (MAS), and hypothyroidism. The predictors of NPSLE were β2GPI-Abs (OR = 4.603), anti-Rib-P Ab (OR = 4.153), and SLEDAI-2K score (OR = 1.215). The study indicates that the SLEDAI-2K score, β2GPI-Abs, and anti-Rib-P Ab were predictors of NPSLE. Our findings may have implications for NPSLE screening in patients with SLE.
Local structural indices changes during different periods of postherpetic neuralgia: a graphical study in structural covariance networks
Authors: Xiong Jiaxin , Gu Lili , Jiang Xiaofeng , Kuang Hongmei , Lv Huiting , Li Zihan , Xie Yangyang , Luo Qing , Jiang Jian 
Published: October 2024

Abstract

There are few studies reflecting the changes in the properties of brain networks in the postherpetic neuralgia (PHN) patients on long time scales. In this study, we aim to explore the changes in network graph theory indices of structural covariance networks (SCNs) in PHN patients with different disease durations. High-resolution T1 magnetic resonance images were collected from 109 subjects including 63 PHN patients, 25 herpes zoster patients and 21 healthy controls(HCs).We constructed SCNs based on cortical thickness and analyzed the changes in global and regional network measures of PHN patients and HZ patients, and get hubs of each group. We found PHN patients with a disease duration > 6 months had reduced global efficiency(P = 0.035) and increased characteristic shortest path length(P = 0.028). It means PHN patients with a disease duration > 6 months had increased SCN integration and diminished information transfer capability between nodes, which complemented the topological properties of previous PHN networks. Global efficiency and shortest path length can be considered as potential imaging markers for future clinical restaging of PHN. Furthermore, the present study found that the node properties of brain regions associated with cognition and emotion were also altered.
The Magnesium Connection: Impact on Erectile Dysfunction and Mortality
Authors: Chen Xiaobao , Xie Ruoyun , Liu Binhong , Lin Junwei , Jiang Wei , Zheng Huaiying 
Published: October 2024

Abstract

This research examines both the cross-sectional and longitudinal relationships between magnesium depletion score (MDS) and erectile dysfunction (ED), as well as all-cause mortality in individuals diagnosed with ED. The analysis utilized data from the National Health and Nutrition Examination Survey (NHANES). To evaluate the correlation between MDS and ED, along with mortality outcomes, weighted multivariate regression and Cox proportional hazards models were employed. Out of the total 3,917 participants, 1,090 were identified as having ED, and 654 individuals succumbed to all-cause mortality. After controlling for potential confounding variables, it was found that each incremental increase of one point in MDS correlated with a 37% heightened risk of developing ED (OR: 1.37, 95% CI: 1.16–1.62). Furthermore, among those with ED, a greater MDS score was linked to a 30% elevation in the risk of all-cause mortality (HR: 1.30, 95% CI: 1.17–1.45). Sensitivity analyses, which included subgroup evaluations and propensity score matching (PSM), validated the robustness of these results. The findings indicate a significant association between MDS and both the prevalence of ED and the risk of all-cause mortality in individuals suffering from ED, highlighting the critical role of magnesium status in the health of men.
Evaluation of cyst treatment technique, cyst type, size differences and healing by fractal analysis
Authors: KAYGISIZ Ömer Faruk , KARSLI Ebru Deniz 
Published: October 2024

Abstract

Aim
The aim of the study was to evaluate the trabeculation increase of treated mandibular cysts..
Material and Method:
The study included 26 female and 33 male patients (mean: 38.4) with cysts larger than 3 cm in the posterior region of the mandible who were admitted to the same centre. Two groups in treatment technique: marsupialisation (n = 29) and enucleation (n = 30). Four groups in cyst types: dentigerous cyst (n = 21), keratocyst (n = 19), radicular cyst (n = 15) and residual cyst (n = 4). Cyst size was divided into two categories: smaller than 5.5 cm (n = 31) and larger than 5.5 cm (n = 28). Panoramic radiographs (PR) of the patients were analysed at the beginning, 6. month and 12. month.
Result
At the end of the treatment, there was no statistically significant difference in terms of Fractal Analysis (FA) between patients treated with marsupialization and enucleation, but considering that the cysts in the marsupialization group were larger in size, a faster increase in FA was observed in the marsupialization group. When the cysts were grouped according to their size, it was observed that healing tissues in cysts smaller than 5.5 cm reached normal FA values faster, while healing in the middle of cysts larger than 5.5 cm took more time.
Conclusions
FA is a reproducible and reliable method. In large cysts, marsupialization results in a faster recovery, but FA values at the end of treatment are similar to the enucleation group.. Cysts larger than 5.5 cm show a more rapid increase in Fractal Dimension(FD). The centre of the cysts is the area that heals the latest. Studies with larger sample sizes are needed to evaluate the difference in healing between cyst types.