bluuebunny/crossref_metadata_2025_split huggingface dataset:
Direct Thrombin Inhibitor Resistance and Possible Mechanisms
Authors: Cardinale Maria , Ha Michael , Liu Michael H. , Reardon David P. 
Published: December 2016

Objective To report 3 cases in which doses of bivalirudin higher than commonly used in clinical practice were required in order to achieve therapeutic anticoagulation as monitored by the activated partial thromboplastin time (aPTT). Case Summary The medical records of 3 patients who required large doses of bivalirudin to remain therapeutic were thoroughly reviewed. In all 3 patients, bivalirudin was initiated at a rate appropriate for the patients' renal function and titrated using a nurse-driven protocol with recommended dose adjustments based on aPTT. Indications for bivalirudin were anticoagulation in intra-aortic balloon pump, treatment of deep vein thrombosis, and heparin-induced thrombocytopenia with thrombosis. Target aPTT was achieved between 25.5 and 134 hours after initiation despite appropriate titration intervals per protocol. Discussion Bivalirudin is a direct thrombin inhibitor frequently used off-label for the medical management of heparin-induced thrombocytopenia. It typically exhibits predictable, dose-dependent anticoagulation. Heparin-induced thrombocytopenia was suspected in 2 of the 3 cases and confirmed in 1. In all 3 patients, target aPTT was initially achieved with doses between 0.456 and 1.0 mg/kg/h after a median of 30.7 hours; up to 1.8 mg/kg/h was required to maintain therapeutic aPTT. In 2 of the cases, the international normalized ratio also increased unexpectedly upon achievement of therapeutic aPTT values. Conclusion Direct thrombin inhibitors may be subject to resistance mechanisms similar to those previously described in patients receiving heparin. The anticoagulation status of these patients remains unknown.
New records of host-parasite relationships between Coenagrion scitulum (Rambur, 1842) (Odonata) and water mite larvae (Hydrachnidia) in core and edge host populations
Authors: Zawal Andrzej , Therry Lieven , Stoks Robby , Michoński Grzegorz 
Published: December 2016

AbstractThe relationships between water mite larvae parasitizing
Anti-Anisakis sp. antibodies in serum of healthy subjects. Relationship with αβ and γδ T cells
Authors: Zamora Vega , García-Ballesteros Carlos , Benet-Campos Carmen , Ballester Ferrán , Cuéllar Carmen , Andreu-Ballester Juan C. 
Published: December 2016

AbstractAnisakiosis is nowadays one of the nematodoses more prevalent in Spain, with rates that oscillate between 0.43% in Galicia (N.W. Spain), and 15.7% and 22.1% in inland and southern regions, respectively. Likewise, it has been proved that
Spermatological characteristics of the enigmatic monogenean Dictyocotyle coeliaca Nybelin, 1941 (Monopisthocotylea: Monocotylidae) reveal possible adaptation to endoparasitism
Authors: Bruňanská Magdaléna , Mackiewicz John S. , Poddubnaya Larisa G. 
Published: December 2016

AbstractSpermatological characters of
Intra and inter species genetic variability of transferrin receptor gene regions in Trypanosoma evansi isolates of different livestock and geographical regions of India
Authors: Sarkhel Souti Prasad , Gupta S.K. , Kaushik Jyoti , Singh Jarnail , Saini Vijesh Kumar , Kumar Sanjay , Kumar Rajender 
Published: December 2016

Abstract, the aetiological agent of Surra affects a wide range of livestock and wild animals in India. In the present study, we studied intra- and inter species genetic variability in the transferrin receptor encoding gene regions
Prevalence and molecular characterization of Theileria equi and Babesia caballi in jereed horses in Erzurum, Turkey
Authors: Guven Esin , Avcioglu Hamza , Deniz Ahmet , Balkaya İbrahim , Abay Ugur , Yavuz Şevki , Akyüz Muzaffer 
Published: December 2016

AbstractEquine piroplasmosis (EP) is a hemoprotozoan tick-borne disease with worldwide distribution that is caused by
Lobbying as a Guard against Extremism
Authors: Zudenkova Galina 
Published: December 2016

AbstractThis paper analyzes endogenous lobbying over a unidimensional policy issue. Individuals differ in policy preferences and decide either to take part in lobbying activities or not. They are assumed to be group rule-utilitarian such that they follow the rule that, if followed by everyone else in their special interest group, would maximize their group’s aggregate welfare. Once formed, lobbies make contributions to the incumbent government in exchange for a policy favor as in a common-agency model. I show the existence of equilibrium with two organized lobbies. Individuals with more extreme preferences are more likely to join lobbying activities. Therefore, the lobbyists are rather extremists than moderates. However, the competition between those extreme lobbies results in a more moderate policy outcome relative to that initially preferred by the biased government. Lobbies therefore guard against extremism, while acting as moderators of the government’s preferences.
Effectiveness of mesenchymal stems cells cultured by hanging drop vs. conventional culturing on the repair of hypoxic-ischemic-damaged mouse brains, measured by stemness gene expression
Authors: Lou Yongli , Guo Dewei , Zhang Hui , Song Laijun 
Published: December 2016

AbstractIn this study, we investigated the therapeutic effects of Human Mesenchymal Stem Cells (hMSCs) cultured by hanging drop and conventional culturing methods on cerebellar repair in hypoxic-ischemic (HI) brain injured mice. Real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR) was used to analyze the expression levels of three stemness genes, Oct4, Sox2 and Nanog, and the migration related gene CXCR4. MSC prepared by hanging drop or conventional techniques were administered intranasally to nine day old mice, and analyzed by MRI at day 28. Results indicate that the MSCs, especially the hanging drop cultured MSCs, significantly improved the mice’s cerebellar damage repair. MSCs derived from the hanging drop culture were smaller than those from the conventional culture. The gene expression levels were significantly increased for the MSCs derived from the hanging drop culture. The mechanism might relate to the fact that the hanging drop cultured MSCs can be kept in an undifferentiated state, resulting in its higher expression level of migration receptor of CXCR4.
Spontaneous rupture of a splenic artery aneurysm during the third trimester of pregnancy
Authors: Peker Nuri , Vicdanlı Nazif Harun , Demir Ahmet , Bozan Mehmet Buğra , Gündoğan Savaş 
Published: December 2016

Abstract
Spontaneous rupture of a splenic artery aneurysm (SAA) during pregnancy is a rare but life-threatening situation typically presenting with sudden and unexpected fetal and maternal death. The etiology is unclear; however, there is a strong association between pregnancy and the rupture of a SAA. Maternal and fetal prognosis is poor and mortality rates remain at 70% and 90%, respectively. Here, we present a case report of the spontaneous rupture of a SAA at the 35th week of gestation, which presented as suddenly developed hypovolemic shock ending in fetal and maternal death.
Eight-Element Antenna Array for LTE 3.4–3.8 GHz Mobile Handset Applications
Authors: Yang Lingsheng , Ji Ming , Cheng Biyu , Ni Bo 
Published: December 2016

Abstract
In this letter, an eight-element Multiple-input multiple-output (MIMO) antenna system for LTE mobile handset applications is proposed. The antenna array consists of eight 3D inverted F-shaped antennas (3D-IFA), and the measured –10 dB impedance bandwidth is 3.2–3.9 GHz which can cover the LTE bands 42 and 43 (3.4–3.8 GHz). By controlling the rotation of the antenna elements, no less than 10 dB isolation between antenna elements can be obtained. After using the specially designed meandered slots on the ground as decoupling structures, the measured isolation can be further improved to higher than 13 dB between the antenna elements at the whole operating band.
Almost Periodic Solution in a Lotka–Volterra Recurrent Neural Networks with Time-Varying Delays
Authors: Yang Li , Li Zhouhong , Pang Liyan , Zhang Tianwei 
Published: December 2016

Abstract:
By means of Mawhin’s continuation theorem of coincidence degree theory and Lyapunov function, some simple sufficient conditions are obtained for the existence and stability of a unique positive almost periodic solution of a delayed Lotka–Volterra recurrent neural networks. To a certain extent, the work in this paper corrects the defect of a recent paper. Finally, an example and simulations are given to illustrate the feasibility and effectiveness of the main result.
Study of the Shock Wave–Turbulent Boundary Layer Interaction Using a 3D von Kármán Length Scale
Authors: Xu Jing-Lei , Song You-Fu , Zhang Yang , Bai Jun-Qiang 
Published: December 2016

Abstract
Traditional turbulence models are initially formulated and calibrated under incompressible conditions. Thus, these models are always of low fidelity when extended to high speed, complex and compressible flows. In this work, a compressible von Kármán length scale is proposed for compressible flows considering the variable densities. The length scale is the ratio between the new vorticity and its gradient. The new length scale is actually based on phenomenological theory, which is then integrated into the KDO (turbulence Kinetic energy Dependent Only) turbulence model, arriving at a compressible model called CKDO (Compressible KDO). In the CKDO turbulence model, all the extra terms produced by compressibility are modeled as dissipation. Compression corners of 8, 16, 20 and 24 angles are studied within SST, SA, KDO and CKDO. These test cases are known as the typical shock wave–boundary layer interactions. The results show that the new length scale in CKDO is able to well capture the surface pressure and skin friction distributions. Besides, compared with the standard von Kármán length scale, the new length scale in CKDO can better capture the size and position of the separation bubble. With the increase of the corner angle, CKDO shows more prominent potential for describing compressible flows.
High efficiency and low roll-off green OLEDs with simple structure by utilizing thermally activated delayed fluorescence material as the universal host
Authors: Zhao Bo , Miao Yanqin , Wang Zhongqiang , Wang Kexiang , Wang Hua , Hao Yuying , Xu Bingshe , Li Wenlian 
Published: December 2016

Abstract
We achieved high-efficiency and low-roll-off green fluorescent and phosphorescent organic light-emitting diodes (OLEDs) simultaneously by adopting the thermally activated delayed fluorescence material of bis[4-(9,9-dimethyl-9,10-dihydroacridine)phenyl]sulfone as the universal host. At a luminance of 1000 cd/m2, fluorescent OLEDs based on C545T get a current efficiency, power efficiency, and external quantum efficiency (EQE) of 31.8 cd/A, 25.0 lm/W, and 9.26%, respectively. This is almost the highest efficiency based on C545T at the luminance of 1000 cd/m2 to date. On the other hand, phosphorescent OLEDs with Ir(ppy)3 as the emitter realize a maximum current efficiency, power efficiency, and EQE of 64.3 cd/A, 62.4 lm/W, and 18.5%, respectively. More important, the EQE remains 17.8% at the representative luminance of 1000 cd/m2 and the roll-off ratio is just 3.78%. The transient photoluminescence decay measurement demonstrates that the up-conversion of host triplet excitons plays a key role in the high efficiency and low roll-off. More detailed discussions are also given.
Synthetic utility of endocyclic cleavage reaction
Authors: Manabe Shino , Ito Yukishige 
Published: December 2016

Abstract
Existence of endocyclic cleavage reaction is now clearly shown from experimental evidence of endocyclic cleavage reaction as well as computational chemistry. Not only stereoelectronic factor, several factors could be main factors for endocyclic cleavage reaction. Endocyclic cleavage reaction is useful for 1,2-cis aminoglycoside formation, which is difficult by conventional glycosylation. By using endocyclic cleavage reaction, several glycosides with 1,2-cis aminoglycoside were prepared.
Quest for electroconducting structural polymers: CNTs/Polybond nanocomposites with improved electrical and mechanical properties
Authors: Sarfraz Muhammad 
Published: December 2016

Abstract
Electroconducting structural polymer-based nanocomposites were prepared by incorporating carbon nanotubes (CNTs) into commercially available Polybond (PB) using the melt compounding technique. The structural, morphological, electrical, thermal, mechanical, and chemical properties of the nanocomposites were investigated via Fourier-transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), differential scanning calorimetry, thermogravimetric analysis, high resistance meter, a Universal Testing Machine (UTM), and chemical resistivity measurements, respectively. FTIR spectra showed the successful grafting of CNT functional groups onto polymer chains. SEM analysis confirmed that the optimum state of dispersion was made for the nanocomposites. Electrical conductivity, melting transition temperatures, mechanical properties, and chemical resistance were improved by incorporating CNTs into PB.
The guilty brain: the utility of neuroimaging and neurostimulation studies in forensic field
Authors: Mameli Francesca , Scarpazza Cristina , Tomasini Emanuele , Ferrucci Roberta , Ruggiero Fabiana , Sartori Giuseppe , Priori Alberto 
Published: December 2016

AbstractSeveral studies have aimed to address the natural inability of humankind to detect deception and accurately discriminate lying from truth in the legal context. To date, it has been well established that telling a lie is a complex mental activity. During deception, many functions of higher cognition are involved: the decision to lie, withholding the truth, fabricating the lie, monitoring whether the receiver believes the lie, and, if necessary, adjusting the fabricated story and maintaining a consistent lie. In the previous 15 years, increasing interest in the neuroscience of deception has resulted in new possibilities to investigate and interfere with the ability to lie directly from the brain. Cognitive psychology, as well as neuroimaging and neurostimulation studies, are increasing the possibility that neuroscience will be useful for lie detection. This paper discusses the scientific validity of the literature on neuroimaging and neurostimulation regarding lie detection to understand whether scientific findings in this field have a role in the forensic setting. We considered how lie detection technology may contribute to addressing the detection of deception in the courtroom and discussed the conditions and limits in which these techniques reliably distinguish whether an individual is lying.
The semiotics of sensation: A. J. Greimas and the experience of meaning
Authors: Schleifer Ronald 
Published: December 2016

AbstractIt has been the life-long ambition of A. J. Greimas to analyze the nature of meaning, and in his work he has consistently described meaning as a felt experience, what he calls the “feeling of understanding.” This essay examines the Greimassian investigation of meaning as experiential – which is to say sensational – as well as cognitive by analyzing, by means of Greimas’s “semiotic square,” P. M. S. Hacker’s recent exploration of the relationship between sensation and cognition undertaken in terms of the semantics of ordinary-language philosophy. That is, the essay subjects what it calls “the illusion of immediacy” in ordinary-language philosophy to the systematic analysis of the “semantic formalism” of the semiotic square in order to demonstrate that the seeming “given” of ordinary language theory – the “logico-grammatical terrain and . . . the conceptual landscape” that Hackers describes – can be profitably analyzed in terms of the interaction of semiotic constraints. It concludes by touching on the ways Greimassian semiotics is congruent with – and perhaps supported by – recent neurological understandings of sensate experience.
Les études de société selon la perspective de la sémiotique greimassienne
Authors: de Barros Diana Luz Pessoa 
Published: December 2016

RésuméLe propos de cette étude est de montrer comment les sémioticiens de ligne française ont contribué, surtout au Brésil, à produire des connaissances sur les discours sociaux. Lors de précédentes études, nous avons montré que l’une des préoccupations majeures des sémioticiens latino-américains était d’expliquer les processus de signification de l’homme et de la société dans leurs pays. Selon nous, la cause en revient à deux questions principales : d’une part, le paradigme dans lequel s’inscrivent la théorie et la méthodologie de la sémiotique ; d’autre part, les conditions d’accueil et de développement de la sémiotique au Brésil et plus généralement en Amérique latine. Trois parties composent notre article : dans la première partie, nous montrons que les relations de la proposition sémiotique avec la société, avec l’histoire et la culture sont préalablement données, en raison du paradigme théorico-méthodologique de la sémiotique et de son projet analytique. Nous y soulignons également que la sémiotique n’implique ni les excès du formalisme qui nie l’histoire, ni ceux de l’idéologisme qui ignore l’intégration entre la réalité sociale et l’organisation linguistique ; dans la deuxième partie, nous traitons des conditions d’accueil de la sémiotique au Brésil et en Amérique latine ; enfin, dans la troisième partie, nous présentons deux exemples brésiliens de ces études de société.
Structural Determination of a DNA Oligomer for a Molecular Spin Qubit Lloyd Model of Quantum Computers
Authors: Yamamoto Satoru , Nakazawa Shigeaki , Sugisaki Kenji , Maekawa Kensuke , Sato Kazunobu , Toyota Kazuo , Shiomi Daisuke , Takui Takeji 
Published: December 2016

Abstract
The global molecular and local spin-site structures of a DNA duplex 22-oligomer with site-directed four spin-labeling were simulated by molecular mechanics (MM) calculations combined with Q-band pulsed electron-electron double resonance (PELDOR) spectroscopy. This molecular-spin bearing DNA oligomer is designed to give a complex testing ground for the structural determination of molecular spins incorporated in the DNA duplex, which serves as a platform for 1D periodic arrays of two or three non-equivalent electron spin qubit systems, (AB)n or (ABC)n, respectively, enabling to execute quantum computing or quantum information processing (Lloyd model of electron spin versions): A, B and C designate non-equivalent addressable spin qubits for quantum operations. The non-equivalence originates in difference in the electronic g-tensor. It is not feasible to determine the optimal structures for such DNA oligomers having molecular flexibility only by the MM calculations because there are many local minima in energy for their possible molecular structures. The spin-distance information derived from the PELDOR spectroscopy helps determine the optimal structures out of the possible ones acquired by the MM calculations. Based on the MM searched structures, we suggest the optimal structures for semi-macromolecules having site-directed multi-spin qubits. We emphasize that for our four molecular spins embedded in the DNA oligomer the Fajer’s error analysis in PELDOR-based distance measurements was of essential importance.
Limited Cognitive Resources Explain a Trade-Off between Perceptual and Metacognitive Vigilance
Authors: Maniscalco Brian , McCurdy Li Yan , Odegaard Brian , Lau Hakwan 
Published: December 2016

Why do experimenters give subjects short breaks in long behavioral experiments? Whereas previous studies suggest it is difficult to maintain attention and vigilance over long periods of time, it is unclear precisely what mechanisms benefit from rest after short experimental blocks. Here, we evaluate decline in both perceptual performance and metacognitive sensitivity (i.e., how well confidence ratings track perceptual decision accuracy) over time and investigate whether characteristics of prefrontal cortical areas correlate with these measures. Whereas a single-process signal detection model predicts that these two forms of fatigue should be strongly positively correlated, a dual-process model predicts that rates of decline may dissociate. Here, we show that these measures consistently exhibited negative or near-zero correlations, as if engaged in a trade-off relationship, suggesting that different mechanisms contribute to perceptual and metacognitive decisions. Despite this dissociation, the two mechanisms likely depend on common resources, which could explain their trade-off relationship. Based on structural MRI brain images of individual human subjects, we assessed gray matter volume in the frontal polar area, a region that has been linked to visual metacognition. Variability of frontal polar volume correlated with individual differences in behavior, indicating the region may play a role in supplying common resources for both perceptual and metacognitive vigilance. Additional experiments revealed that reduced metacognitive demand led to superior perceptual vigilance, providing further support for this hypothesis. Overall, results indicate that during breaks between short blocks, it is the higher-level perceptual decision mechanisms, rather than lower-level sensory machinery, that benefit most from rest.SIGNIFICANCE STATEMENTPerceptual task performance declines over time (the so-called vigilance decrement), but the relationship between vigilance in perception and metacognition has not yet been explored in depth. Here, we show that patterns in perceptual and metacognitive vigilance do not follow the pattern predicted by a previously suggested single-process model of perceptual and metacognitive decision making. We account for these findings by showing that regions of anterior prefrontal cortex (aPFC) previously associated with visual metacognition are also associated with perceptual vigilance. We also show that relieving metacognitive task demand improves perceptual vigilance, suggesting that aPFC may house a limited cognitive resource that contributes to both metacognition and perceptual vigilance. These findings advance our understanding of the mechanisms and dynamics of perceptual metacognition.
L’Écriture de voyage d’après Les Mémoi­res de Joseph Frank
Authors: Dručkutė Genovaitė 
Published: December 2016

Straipsnyje Jozefo Franko Memuarai analizuojami kaip pasakojimas apie kelionę. Susitelkiama į vil­nietiškąjį laikotarpį, apimantį 1804–1823 metus, kai daktaras Frankas dirbo Vilniaus universiteto pro­fesoriumi. Aptarus žanrinius Memuarų ypatumus, parašymo aplinkybes, autoriaus tikslą ir vertimus iš prancūzų kalbos į kitas kalbas, toliau tiriama ke­liautojo žvilgsnio struktūra, nagrinėjama centro ir periferijos problema. Keliautojo žvilgsnį apibūdina nuostaba, pastanga lyginti ir vertinti. Į jo akiratį pa­tenkanti aplinka vertinama sumaišties, kaitos, suiru­tės, nepastovumo, maišto ir tvarkos opozicijomis. Vilnius ir universitetas laikomi bandymų lauku, tam tikra antiutopija. Franko Memuaruose Vilniaus uni­versitetas iškyla kaip miesto centras, pažangių idėjų kūrimo ir įgyvendinimo vieta.