bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a green spectrophotometric method for simultaneous determination of combined pharmaceutical dosage form (paracetamol and caffeine) using chemometrics technique in comparison with HPLC
Authors: Alattab Bushra , Alarbagi Fares Abdullah , Almaqtari Maher Ali , Alhuraishi Entesar , Al-Maydama Hussein 
Published: October 2024

A green analytical method, a simple, fast, and cost-effective simultaneous spectrophotometric method using two chemometric techniques, the partial least square regression (PLS) and principal component regression (PCR), for determining a combination of paracetamol and caffeine in pharmaceutical formulations was developed. Pretreatment and separation steps are not required in the proposed method. For model construction and validation, various drug concentrations and instrumental spectra of 25 mixed solutions of paracetamol and caffeine were analyzed. The UV analysis of the prepared mixtures was recorded for a selected solvent blank in the wavelength range of 210-300 nm. The digitized absorbance was sampled at 0.2-nm intervals. R2 values of 0.9993 and 0.9994 assigned for the PLS of paracetamol and caffeine and 0.9995 and 0.9991 for the PCR of paracetamol and caffeine, respectively, exhibited greater prediction efficiencies. The obtained results were statistically compared with the results of the HPLC reference method. Concerning accuracy and precision, the statistical comparison revealed no significant differences between the suggested and reference HPLC approaches.
Old Wounds and New Science
Authors: Levin Amy 
Published: October 2024

Review essay on four books about Indigeneity that relate to museums that were published in 2023:
Janet Catherine Berlo, Not Native American Art: Fakes, Replicas, and Invented Traditions.
Jeffrey Gibson, ed, An Indigenous Present.
Cressida Fforde, Hilary Howes, Gareth Knapman, and Lyndon Ormond-Parker, eds, Repatriation, Science, and Identity.
Emma Kowal, Haunting Biology: Science and Indigeneity in Australia.
Selecting the Best Theory to Explain the Formation of Different Universities Based on Sadra’s Philosophy
Authors: Babakhan Alireza , Shafia Mohammad Ali , Rafiei Atani Ata Allah , Aliahmadi Alireza 
Published: October 2024

In recent years, the role of universities in the development of societies has increased. In Iran, as in other countries, universities have made changes to their programs, but it still seems they need some new policies to strengthen the impact of universities on the development of society. While explaining the reasons for the formation of existing universities at the international level, this article attempts to use the framework of Sadra's philosophy to present a new type of university called “wisdom-oriented” university. This university activates the four functions as follows: Graduate education, Development of technology and technical knowledge, Problem-solving and communicating with society (such as industry, government institutions, etc.), and Producing and disseminating of knowledge content. If the wisdom-based university is formed and institutionalized, the following characteristics could be expected: “Avoidance of particularity”, “attention to comprehensiveness and gradual shift to specialization”, “scientific moderation and attention to wisdom”, “fostering creativity, production and accumulation of knowledge content”, “duty-oriented interaction with society”, “unbounded activity”, “continuous effort to come closer to God” and “optimal use of science and technology.”
Impact of ceramic packaging on the quality and safety of Armenian fermented dairy product Matsoun
Authors: Esoyan Syuzanna , Hayrapetyan Ani , Yesayan Tigran , Sargsyan Armine , Chakhmakhchya Armine , Babayan Bella , Sevoyan Garegin , Yesayan Aleksandr 
Published: October 2024

Background: Packaging is essential for food safety, as it acts as a barrier against contaminants that can cause spoilage and affect human health. The Armenian fermented dairy product, matsoun, is packaged not only in plastic and glass but also in clay pots. However, the impact of traditional packaging on the quality and safety of matsoun, especially heavy metal migration, remains under-researched.
Objective: This study aimed to investigate the impact of ceramic packaging material on the quality and safety of matsoun during storage. Specifically, it compared the physicochemical properties (pH, titratable acidity), lactic acid bacteria (LAB) populations, and metal migration during storage.
Methods: Six samples of matsoun were prepared and packaged in sterilized glass and ceramic containers. The samples were stored at 4 °C and analyzed on days 1, 7, and 15 of storage. The parameters measured included pH, titratable acidity, and LAB counts (coccus and bacillus). Heavy metal migration (Cd, Pb, Hg, As) was analyzed using atomic absorption spectroscopy.
Results: The pH of samples packaged in ceramic and glass containers decreased over 15 days of storage, from 4.61 to 4.24 and 4.6 to 4.27, respectively. Titratable acidity increased in both groups, reaching 1.2 % lactic acid. A decrease in bacilli was observed in ceramic-packaged matsoun. The lead concentration remained constant at 0.0045 ppm across all samples. In ceramic containers, cadmium concentration increased from 0.0015 ppm to 0.0029 ppm by day 15.
Conclusion: This study observed a decrease in pH, an increase in titratable acidity, and a relatively constant number of lactic acid bacteria indicating ongoing fermentation. The results showed nondetectable concentrations of arsenic (As) and mercury (Hg). The lead (Pb) concentration in all samples remained within the World Health Organization’s (WHO) allowed limit of 0.02 ppm. However, the concentration of cadmium (Cd) concentration in ceramic-packed increased, exceeding the WHO limit of 0.002 ppm. Further research is necessary to identify the sources of cadmium contamination.
Keywords: food packaging, ceramic, matsou​​n​, heavy metal migration, food safety
Peran Budaya Organisasi Dan Efikasi Diri Dalam Kinerja Karyawan Melalui Kepuasan Kerja Sebagai Variabel Mediasi
Authors: Achmadi Achmadi , Sumail La Ode , Heslina Heslina 
Published: October 2024

Mimpi besar Bank Permata Tbk adalah menjadi bank Top Ten dapat diwujudkana melalui strategi pembalikan arah (Turnaround) dicurigai memakai budaya organisasi dan memiliki efikasi diri. Oleh karena itu, tujuan penelitian adalah mengivestigasi pengaruh budaya organisasi dan efikasi diri terhadap kinerja karyawan melalui kepuasan kerja. Teknik penarikan sampel menggunakan metode sampel jenu, dimana seluruh jumlah popolasi dijadikan sebagai sampel karena terbatas jumlah sampel sebanyak 59 orang sebagai responden pada PT Bank Permata Tbk (PermataBank) Cabang Makassar. Penelitian ini menemukan bahwa budaya organisasi berpengaruh positif dan signifikan terhadap kinerja karyawan, namun efikasi diri tidak berpengaruh signifikan terhadap kinerja karyawan. Budaya organisasi berpengaruh positif dan signifikan terhadap efikasi. Selanjutnya, budaya organisasi dan efikasi diri berpengaruh positif dan signifikan terhadap kepuasan kerja. Kemudian, budaya organisasi berpengaruh positif dan signifikan terhadap kinerja karyawan melalui kepuasan kerja. Pula, efikasi diri berpengaruh positif dan signifikan terhadap kinerja karyawan melalui kepuasan kerja.. Teakhir, budaya organisasi terhadap kepuasan kerja melalui kepuasan kerja.
ANALISIS FRAMING PEMBERITAAN POTENSI TSUNAMI 28 METER DI PESISIR PACITAN JAWA TIMUR (CNN INDONESIA.com DAN SINDONEWS.com)
Authors: Supriatno Djoko , Syah Putra Hilman 
Published: October 2024

Abstrak

Penelitian ini berjudul “ANALISIS FRAMING PEMBERITAAN POTENSI TSUNAMI 28 METER DI PESISIR PACITAN JAWA TIMUR (CNN INDONESIA.com DAN SINDONEWS.com)” tentang pemberitaan yang dilakukan oleh media online CNN Indonesia.com dan SINDOnews.com yang mengulas tentang hasil simulasi dari Badan Meteorologi Klimatologi dan Geofisika (BMKG) terkait gempa dan Tsunami yang berpusat di Pacitan. Tujuan dari penilitian ini adalah untuk mengetahui bagaimana CNN Indonesia dan Sindonews membingkai pemberitaan peringatan BMKG tsunami 28 meter wilayah selatan jawa timur serta untuk mengetahui perbedaan framing yang di lakukan oleh CNN Indonesia dan Sindonews. Teori yang digunakan untuk mengupas penelitian ini adalah Teori Komunikasi, Teori Komunikasi Massa, Teori Kontruksi Realitas Sosial, Framing. Objek penelitian yang diteliti adalah satu pemberitaan dari masing-masing media yang mengulas tentang hasil kontruksi BMKG pada tanggal 12 september 2021. Metode yang digunakan oleh peneliti adalah metode kualitatif dengan paradigma konstruktivis. Teknik analisis yang digunakan adalah model analisis framing Zhongdang Pan dan Gerald M. Kosicki. Hasil penelitian menunjukkan bahwa pembingkaian berita yang dilakukan oleh CNN Indonesia dan Sindonews sama-sama memuat tentang kutipan dan pernyataan dari kepala BMKG terkait hasil simulasi dan hal-hal yang harus dilakukan oleh pemerintah daerah dan masyarakat mengenai potensi gempa dan Tsunami 28 meter di pacitan. Perbedaan dari kedua media hanya berkaitan mengenai bagaimana realitas tersebut di bingkai, CNN Indonesia dalam hal ini lebih memainkan realitas untuk mendapat perhatian dari khalayak umum.
Evaluation of the relationship between thyroid cancer and the concurrent detection of thyroid nodules on the background of primary hyperparathyroidism
Authors: Poppen Alisha 
Published: October 2024

Introduction: Primary Hyperparathyroidism (PHPT) is commonly caused by a benign parathyroid adenoma that results in overactivity of the gland and subsequent hypercalcemia due to elevated parathyroid hormone (PTH). This endocrine pathology is associated with thyroid cancer, specifically Papillary Thyroid Cancer (PTC). However, the explanation for their synchronous presentation is unknown. Moreover, it causes diagnostic and treatment challenges that impact patient outcomes.
Aims and Objectives: To critically analyze published research to address the relationship between PHPT and thyroid cancer, the role of ultrasound imaging in detecting sinister thyroid nodules in PHPT patients and the features of PHPT that predispose the risk of thyroid malignancy.
Study Design: Literature Review
Methodology: Electronic database searches of PubMed and CINAHL Plus through EBSCOhost were conducted using the keywords "primary hyperparathyroidism", "thyroid nodules" and "thyroid cancer". Following application of filters and removal of duplicates, 627 relevant results remained. Articles were screened for eligibility based on predetermined selection criteria. Following a review of titles and abstracts, 10 peer-reviewed articles were chosen for further analysis. The studies included were critically appraised using the EBL Critical Appraisal Checklist.
Results: 10 articles were examined, 2 were prospective cohort studies and 8 were retrospective cohort studies. All studies involved exhaustive medical chart reviews of patients with PHPT, to investigate the concomitance of thyroid malignancy. Six studies established cervical ultrasound as the optimal method of recognition and preoperative localization of thyroid and parathyroid lesions. Overall, the incidence of thyroid cancer among PHPT patients ranged between 2.9% to 32.9%. Four studies established age, gender and PTH levels as risk factors.
Conclusion: The existing literature is consistent with previous studies and purports that individuals with a background fo PHPT are at an increased risk of thyroid cancer. Furthermore the highest likelihood of identifying thyroid cancer is through preoperative localization of parathyroid adenomas by cervical ultrasound, in female patients over the age of 50.
Key Findings: Further research is needed to understand the underlying pathogenesis and genetic mechanisms that encompass the relationship between PHPT and thyroid cancer.
Marketing de serviços de saúde: a satisfação dos beneficiários de planos odontológicos do município de Petrópolis, Rio de Janeiro
Authors: Tavares Lorrane de Souza , Franco Décio Henrique 
Published: October 2024

Na saúde, em especial no setor privado de assistência odontológica, diferenciação nem sempre é possível, por isso a qualidade dos serviços e a excelência no atendimento são essenciais na conquista da satisfação do cliente. O objetivo deste artigo foi medir a satisfação dos clientes usuários de planos odontológicos do município de Petrópolis, no Rio de Janeiro, bem como compreender o marketing de serviços na saúde, através da aplicação de um questionário online respondido por 116 pessoas. Foi possível identificar que 72% não recebeu nenhum tipo de contato por parte da operadora, porém quando este usuário necessita recorrer aos serviços de atendimento, 57% deles dizem ser bem atendidos. Constatou-se que 65% dos beneficiários estão satisfeitos com seus planos, mas alguns pontos precisam de melhorias, como o aumento da rede credenciada, a cobertura dos procedimentos e ampliar o hábito de se comunicar e relacionar com os clientes. Dentre as propostas está o monitoramento por parte das empresas, dos serviços prestados.
Palavras-Chave: Mercado de Serviços de Saúde. Planos de Assistência Odontológica. Satisfação dos Usuários. Odontologia. Serviços Odontológicos.

Abstract: In healthcare, especially in the private dental care, differentiation is not always possible, which is why the quality of services and excellence in care are essential in achieving customer satisfaction. The objective of this article was to measure the satisfaction of customers using insurance dental in the city of Petrópolis, in Rio de Janeiro, as well as to understand the marketing of health services, through the application of an online questionnaire answered by 116 people. It was possible to identify that 72% did not receive any type of contact from the operator, but when this user needs to resort to customer service, 57% of them say they are well attended to. It was found that 65% of beneficiaries are satisfied with their plans, but some points need improvement, such as increasing the accredited network, coverage of procedures and expanding the habit of communicating and relating to customers. Among the proposals is monitoring by companies of the services provided.
Keywords: Health Services Marketing. Insurance Dental. Satisfaction Consumer. Dentistry. Dental Care.
Vericiguat combined with “new quadruple” therapy enhances cardiac function and life quality in patients with heart failure: a single-center prospective study
Authors: Zhao Di , Zhang Yanjuan , Yong Yonghong , Wang Liansheng , Liu Jiabao 
Published: October 2024

ObjectiveTo investigate the therapeutic effect of Vericiguat combined with “new quadruple” drugs on patients with heart failure (HF).MethodsFrom December 1, 2022 to February 1, 2024, 103 patients with heart failure were consecutively enrolled from the cardiology clinic or ward of the First Affiliated Hospital of Nanjing Medical University. Before enrollment, the patients’ left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDD), N-terminal pro-B-type natriuretic peptide (NT-proBNP), liver and kidney function electrolytes, and Minnesota Living with Heart Failure Questionnaire (MLHFQ) and other indicators were measured. Patients diagnosed with reduced ejection fraction (HFrEF) and with heart failure with mildly reduced ejection fraction (HFmrEF) were treated with Vericiguat combined with “ARNI, BB, MRA, SGLT2i” therapy. Patients diagnosed with preserved ejection fraction (HFpEF) were treated with Vericiguat combined with “ARNI, BB, SGLT2i” therapy. The above indicators were rechecked after 1 month of treatment.ResultsFor all patients, comparison after treatment: LVEF (38.1 ± 8.5% vs. 43.1 ± 8.5%, P &lt; 0.01), LVEDD (60.5 ± 8.1 vs. 58.2 ± 7.3 mm, P &lt; 0.01), NT-proBNP (4,567.8 ± 5,163.9 vs. 1,895.6 ± 2,702.1 ng/L, P &lt; 0.01), MLHFQ (45.72 ± 11.09 vs. 32.29 ± 9.41, P &lt; 0.01). Further subgroup analysis showed that Vericiguat combined with “ARNI, BB, SGLT2i or MRA” improved the LVEF and reduced NT-proBNP levels in patients with HFrEF, HFmrEF or HFpEF. and improved patients’ quality of life scores. The intergroup comparison showed the therapeutic effect of the combination was equivalent in HF caused by myocardial Infarction (MI), dilated cardiomyopathy (DCM) or Valvular Heart Disease (VHD).ConclusionVericiguat combined with the “new quadruple” therapy has a significant therapeutic effect on patients with heart failure caused by MI, DCM or VHD.
Effect of double adhesive layer application on micro-tensile dentin bond strength of a universal adhesive
Authors: Al-Zain Afnan O. , Albuqayli Asrar , Albogami Abdulaziz , Alkudsi Abdulghani , Alwabiri Meshari , Koshak Abdullah T. , Alsefri Hattan , Munchow Eliseu A. 
Published: October 2024

IntroductionAchieving optimal dentin bond strength is crucial for the long-term success of adhesive restorations. This study aims to evaluate the impact of double adhesive layer application, with and without light curing between applications, on the micro-tensile dentin bond strength (µ-TBS) of a universal adhesive, in comparison to the conventional single-layer application.MethodsIntact human molars were divided into three groups (n = 15) according to the adhesive application technique using a universal self-etch adhesive (Tetric N-Bond Universal, Ivoclar) as follows: (1) according to the manufacturer's instructions, (2) double-layer application without light curing between layers, and (3) double-layer application with light curing between layers. Samples were immediately tested for µ-TBS, with failure types recorded as adhesive, cohesive, or mixed. Representative samples were observed by scanning electron microscopy. Data were analyzed using multiple-way ANOVA (α = 0.05).ResultsThe double adhesive layer with and without light curing between layers showed similar μ-TBS to that of the control group (p &gt; 0.05).DiscussionFrom a clinical perspective, these findings suggest that the accurate application of a single layer of a universal adhesive can be as effective as more complex techniques. Additionally, the use of universal bonding agents may have contributed to the outcomes observed in this study. In conclusion, double adhesive layer application and light curing between adhesive layers did not increase the µ-TBS with the universal adhesive agent explored.
Adolescent close friendships, self-perceived social acceptance, and peer-rated likeability as predictors of wellbeing in young adulthood
Authors: Shah Emily N. , Szwedo David E. , Allen Joseph P. 
Published: October 2024

IntroductionLinks between interpersonal relationships and physical and psychological functioning have been well-established in the literature. During adolescence, success or distress in peer relationships may have distinct effects on different aspects of wellbeing. The present study aims to examine the ways in which different adolescent peer relationship contexts (i.e., close friendship quality, social acceptance, and likability from peers) can predict outcomes relevant to adult wellbeing (i.e., social anxiety, depression, aggression, social integration, romantic insecurity, job satisfaction, and physical health). Further, the study considers how different developmental stages of adolescence may impact links between peer relationships and wellbeing outcomes.MethodPeer relationship contexts were assessed in early (ages 13–14) and late (ages 17–18) adolescence. Markers of wellbeing were measured in young adulthood (ages 28–30). A path analysis was used to examine whether the developmental timing of adolescent peer relationship contexts could predict wellbeing in young adulthood.ResultsResults suggest that, across adolescence, broader perceived social acceptance may be a more robust predictor of adult wellbeing compared to close friendship quality and peer likability. When examined at early and late adolescence separately, early adolescent social acceptance and late adolescent close friendship quality best predicted outcomes of adult wellbeing.DiscussionImplications and considerations for future research are discussed.
Multifactorial analysis of risk factors for foot ulcers in patients with neurovascular complications of diabetes
Authors: Fan Zibo , Huang Jinyan , Liu Yue , Xie Hao , Yang Qinfeng , Liang Yue , Ding Hong 
Published: October 2024

BackgroundDiabetic foot ulcers (DFU) are a major complication associated with significant morbidity and mortality. While numerous studies have investigated risk factors for these ulcers in general, few have focused specifically on patients with Neurovascular Complications of Diabetes. This study aimed to evaluate the prevalence and risk factors for DFU in this specific population.MethodsWe analyzed data from the National Institutes of Health (NIS) database for the years 2017-2019, involving a cohort of 161,834 patients aged over 18 who were diagnosed with neurovascular complications of diabetes. Demographic characteristics (age, gender, ethnicity), hospital characteristics, comorbidities, and other relevant data were included for analysis. A binary logistic regression model was generated to identify independent risk factors for DFU.ResultsThe prevalence of DFU among patients with neurovascular complications of diabetes was 29.4% during the period from 2017 to 2019. Compared to patients without DFU, those with DFU had longer hospitalization times and higher costs. The multiple regression analysis revealed that Iron-deficiency anemia (OR, 1.10; 95% CI, 1.01-1.11; P=0.019), Hypertension (OR, 1.07; 95% CI, 1.03-1.11; P=0.001), Obesity (OR, 1.08; 95% CI, 1.06-1.11; P&lt;0.001), Peripheral vascular disorders (PVD) (OR, 1.69; 95% CI, 1.65-1.74; P&lt;0.001), Osteomyelitis (OR, 7.10; 95% CI, 6.89-7.31; P&lt;0.001), Tinea pedis (OR, 1.89; 95% CI, 1.59-2.26; P&lt;0.001), Sepsis (OR, 1.24; 95% CI, 1.20-1.28; P&lt;0.001), and onychomycosis (OR, 1.26; 95% CI, 1.13-1.42; P&lt;0.001) were independent predictors for DFU in this population.ConclusionThe study found a high prevalence of DFU in patients with neurovascular complications of diabetes. Identifying and addressing risk factors such as deficiency anemia, hypertension, obesity, PVD, infections, and foot conditions may contribute to reducing the prevalence of DFU in this vulnerable population.