bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Color Doppler Ultrasonography in Differentiation of Graves’ Disease from Thyroiditis: A Prospective Study
Authors: Suresh Rv , Sundarram, KS Thalavai , Sadacharan, Dhalapathy , Ravikumar, Krishnan , Kalpana, S 
Published: August 2017

ABSTRACT

Introduction
Thyrotoxicosis due to Graves’ disease (GD) and destructive thyroiditis (DT) needs differentiation, as management strategy differs. Factors that help in diagnosis are biochemical and nuclear imaging. Utility of high-resolution ultrasonography (HRUSG) and color Doppler (CD) in differentiation is not widely practiced. We undertook the prospective study in the Department of Endocrine Surgery at a tertiary care center among South Indian population in 1 year as a cost-effective model

Materials and methods
Out of 120 newly diagnosed thyrotoxicosis patients, 54 were GD (group I) and 66 were DT (group II) patients. Totally, 55 euthyroid patients served as controls. Parameters analyzed were demography, free thyroid function test (TFT) anti-thyroid-stimulating hormone receptor antibody (TSHrAB), antithyroid peroxidase antibody (ATPO), anti-thyroglobulin antibody (ATG), and Tc-99m thyroid scintigraphy. Parameters analyzed using HRUSG and CD were peak systolic velocity (PSV), end-diastolic volume (EDV), pulsatility index (PI), resistive index (RI) of bilateral superior thyroid artery (STA) and inferior thyroid artery (ITA).

Results
Both groups were age and sex matched. The TFT, ATPO, and ATG were comparable between both groups (p = 0.609). The TSHrAB (IU/mL) was significantly higher in group I (36.11 ± 0.82) than group II (1.23 ± 0.24) (p < 0.001). Mean thyroid volume (mL) was higher in group I (28.9 ± 14.9) than group II (26.2 ± 8.81) (p = 0.022). Mean PSV-STA (cm/s) was statistically higher in group I (54.09 ± 4.67) than group II (28.92 ± 4.39) (p ≤ 0.001). Mean PSV-ITA (cm/s) was higher in group I (32.11 ± 2.45) than group II (25.23 ± 3.45) (p = 0.006). Other parameters measured in both arteries like mean EDV (cm/s), mean RI, and mean PI were comparable between both groups.

Conclusion
The HRUSG with CD evaluation of PSV STA and ITA is a cost-effective alternative to TSHrAB and thyroid scintigraphy in differentiating GD from DT patients. Additionally, we observed that PSV in STA was higher than in ITA in patients with GD. To conclude, HRUSG and CD are simple, cost-effective, and widely available tools in the differentiation of GD from DT.

How to cite this article
Sundarram KST, Sadacharan D, Ravikumar K, Kalpana S, Suresh RV. Role of Color Doppler Ultrasonography in Differentiation of Graves’ Disease from Thyroiditis: A Prospective Study. World J Endoc Surg 2017;9(2):41-45.
Lingual Papillary Thyroid Carcinoma with Bilateral Neck Node Metastasis
Authors: Singh Sachender Pal , Jain Devendra K , Das, Subhabrata 
Published: August 2017

ABSTRACT
Incidence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 in general population and lingual thyroid is the most common ectopic site (90%). The number of reported neoplasms occurring in this tissue seems disproportionately small when compared with the frequency of tumor formation in the normally placed thyroid. Till now only 51 cases of lingual thyroid cancer have been reported in the literature.
We are reporting a case of lingual thyroid carcinoma with bilateral cervical metastasis and absent orthotopic thyroid gland. In our case we approach the tumor via midline lip splitting with lateral mandibulotomy approach which provides us a good exposure of the entire oropharynx (tumor). We have managed the tumor according to the guidelines of differentiated thyroid cancer because of non availability of guidelines for ectopic thyroid cancer. After surgical excision of lingual thyroid and neck dissection radioiodine therapy was given.
The surgical approach to a lingual thyroid cancer as well as adjuvant therapy and natural history remains to be ascertained due to the rarity of the disease. Lip splitting with lateral mandibulotomy and swing approach appears to give adequate exposure to lingual thyroid.

How to cite this article
Singh SP, Das S, Jain DK. Lingual Papillary Thyroid Carcinoma with Bilateral Neck Node Metastasis. World J Endoc Surg 2017;9(2):68-71.
Mini-implant supported Orthodontic Molar Intrusion: An Unconventional Approach for Pre-implant Prosthetics
Authors: Mehta Prathmesh R , Bhimani Rishi A , Badavannavar Anand N 
Published: August 2017

ABSTRACT
Aim
To demonstrate two cases in which mini-implant-supported orthodontic molar intrusion has been performed to regain ideal crown height space (CHS) for implant prosthesis.

Background
Tooth loss is associated with esthetic, functional, and psychological consequences on an individual. Replacement of missing teeth by dental implants has gained significant importance due to promising advantages of implants over conventional prosthesis. Edentulism often results in supra-eruption of antagonistic teeth into the edentulous site, resulting in reduced vertical dimension for tooth replacement, posing a restorative challenge for clinicians. Hence, it is necessary to regain the lost vertical dimension prior to the implant prosthesis, either conventionally by endodontic and prosthetic intervention or by orthodontic intrusion with the aid of temporary anchorage devices (TADs). Mini-implants are a category of TADs that provide a minimally invasive technique for molar intrusion.

Case report
Two patients with missing mandibular molars desiring tooth replacement presented with supra-eruption of antagonist teeth, posing a difficulty during prosthetic treatment. Orthodontic intrusion using mini-implants was performed to regain the lost vertical space simultaneously along with dental implant placement followed by prosthetic rehabilitation.

Conclusion
The present twin case report demonstrates the successful role of mini-implants in orthodontic molar intrusion for establishing an ideal CHS for implant prosthesis to reestablish masticatory function.

Clinical significance
The twin case report demonstrates mini-implant-supported orthodontic molar intrusion as a replacement for conventional gross tooth reduction, for regaining the lost vertical space in cases of supra-eruption of maxillary molar associated with edentulism.

How to cite this article
Mehta PR, Bhimani RA, Badavannavar AN. Mini-implant supported Orthodontic Molar Intrusion: An Unconventional Approach for Pre-implant Prosthetics. Int J Oral Implantol Clin Res 2017;8(1):26-30.
Fractured Miniscrew Retrieval through Flapless Vibration Technique: A Mini Review and Case Report
Authors: Rath Sunil K , Swain Choudhury S , Panda Subhashree M 
Published: August 2017

ABSTRACT
Nowadays, miniscrew anchorage system is encouraged to obtain better results in orthodontic treatment. This system also brings emergency complications like fractures during insertion of these miniscrews. According to protocol flap-raising technique, a periodontist should be consulted during retrieval of the fractured miniscrew. Here, we propose a new technique that can retrieve the fractured implant with uneventful healing by the vibration of micromotor blunt burs or ultrasonic scaler tips with reinsertion in 7 days.
How to cite this article
Rath SK, Swain CS, Panda SM. Fractured Miniscrew Retrieval through Flapless Vibration Technique: A Mini Review and Case Report. Int J Oral Implantol Clin Res 2017;8(1):31-33.
PathfinderTURB: an automatic boundary layer algorithm. Development, validation and application to study the impact on in situ measurements at the Jungfraujoch
Authors: Poltera Yann , Martucci Giovanni , Collaud Coen Martine , Hervo Maxime , Emmenegger Lukas , Henne Stephan , Brunner Dominik , Haefele Alexander 
Published: August 2017

Abstract. We present the development of the PathfinderTURB algorithm for the analysis of ceilometer backscatter data and the real-time detection of the vertical structure of the planetary boundary layer. Two aerosol layer heights are retrieved by PathfinderTURB: the convective boundary layer (CBL) and the continuous aerosol layer (CAL). PathfinderTURB combines the strengths of gradient- and variance-based methods and addresses the layer attribution problem by adopting a geodesic approach. The algorithm has been applied to 1 year of data measured by two ceilometers of type CHM15k, one operated at the Aerological Observatory of Payerne (491 m a.s.l.) on the Swiss plateau and one at the Kleine Scheidegg (2061 m a.s.l.) in the Swiss Alps. The retrieval of the CBL has been validated at Payerne using two reference methods: (1) manual detections of the CBL height performed by human experts using the ceilometer backscatter data; (2) values of CBL heights calculated using the Richardson's method from co-located radio sounding data. We found average biases as small as 27 m (53 m) with respect to reference method 1 (method 2). Based on the excellent agreement between the two reference methods, PathfinderTURB has been applied to the ceilometer data at the mountainous site of the Kleine Scheidegg for the period September 2014 to November 2015. At this site, the CHM15k is operated in a tilted configuration at 71° zenith angle to probe the atmosphere next to the Sphinx Observatory (3580 m a.s.l.) on the Jungfraujoch (JFJ). The analysis of the retrieved layers led to the following results: the CAL reaches the JFJ 41 % of the time in summer and 21 % of the time in winter for a total of 97 days during the two seasons. The season-averaged daily cycles show that the CBL height reaches the JFJ only during short periods (4 % of the time), but on 20 individual days in summer and never during winter. During summer in particular, the CBL and the CAL modify the air sampled in situ at JFJ, resulting in an unequivocal dependence of the measured absorption coefficient on the height of both layers. This highlights the relevance of retrieving the height of CAL and CBL automatically at the JFJ.
Evolution of the vegetation system in the Heihe River basin in the last 2000 years
Authors: Li Shoubo , Zhao Yan , Wei Yongping , Zheng Hang 
Published: August 2017

Abstract. The response of vegetation systems to the long-term changes in climate, hydrology, and social–economic conditions in river basins is critical for sustainable river basin management. This study aims to investigate the evolution of natural and crop vegetation systems in the Heihe River basin (HRB) over the past 2000 years. Archived Landsat images, historical land use maps and hydrological records were introduced to derive the long-term spatial distribution of natural and crop vegetation and the corresponding biomass levels. The major findings are that (1) both natural and crop vegetation experienced three development stages: a pre-development stage (before the Republic of China), a rapid development stage (Republic of China – 2000), and a post-development stage (after 2000). Climate and hydrological conditions did not show significant impacts over crop vegetation, while streamflow presented synchronous changes with natural vegetation in the first stage. For the second stage, warmer temperature and increasing streamflow were found to be important factors for the increase in both natural and crop vegetation in the middle reaches of the HRB. For the third stage, positive climate and hydrological conditions, together with policy interventions, supported the overall vegetation increase in both the middle and lower HRB; (2) there was a significantly faster increase in crop biomass than that of native vegetation since 1949, which could be explained by the technological development; and (3) the ratio of natural vegetation to crop vegetation decreased from 16 during the Yuan Dynasty to about 2.2 since 2005. This ratio reflects the reaction of land and water development to a changing climate and altering social–economic conditions at the river basin level; therefore, it could be used as an indicator of water and land management at river basins.
Brodie abscess of the jaw: An unusual presentation of a rare complication of subacute osteomyelitis
Authors: D'souza Melroy , Xu Jack , John Elizabeth , Parikh Payal 
Published: August 2017

Background: A Brodie abscess is a rare subtype of subacute osteomyelitis which can be acquired from local trauma or hematogenous spread secondary to transient bacteremia. However, to date there have been no reports of the presence of a Brodie abscess in the mandible.Case representation: Here we report a case of a 51-year-old female who presented to the emergency department with a 4-day history of left sided facial pain and trismus after recent dental manipulation. A computed tomography (CT) scan showed the presence of osteomyelitis with a Brodie abscess in the mandibular condyle. Empiric treatment was initiated with ampicillinsulbactam. After seven days of treatment, the antibiotics were switched to ceftriaxone and metronidazole on discharge. Five days later the patient returned to the hospital with the same symptoms that she initially presented with, indicating a failure of treatment. Follow-up CT scan showed the persistence of the Brodie abscess. Subsequently, IV ertapenem was initiated for a duration of eight weeks and the patient was instructed to obtain an oral surgery evaluation as an outpatient.Conclusions: This case highlights a unique presentation of a Brodie abscess, which has been previously exclusively found in long bones, and raises awareness of such a complication in patients whose facial erythema, pain, and swelling may not improve with first line therapy for a simple dental infection. Additionally, we highlight that the unique location of the mandibular condyle poses a treatment challenge and surgical replacement of the jaw appears to be the lone curative modality.
Importância clínica do músculo esternal e suas variações anatômicas: uma revisão sistemática da literatura
Authors: Oliveira Luana Agapito de , Quintana Hananiah Tardivo , Oliveira Flavia De 
Published: August 2017

A presença do músculo esternal é uma variação anatômica que está situada anteriormente ao osso esterno e suas estruturas adjacentes e não tem função totalmente definida. Há na literatura mais relatos de estudos anatômicos sobre o músculo esternal do que sobre as implicações clínicas da sua presença. O objetivo deste estudo foi analisar as descrições existentes das variações anatômicas do músculo esternal, compreendendo, assim, a importância clínica desse conhecimento. Foram avaliados artigos nas línguas portuguesa e inglesa, indexados nas bases de dados PubMed e SciELO, publicados entre 1867 e 2016. Buscou-se verificar os tipos de variações anatômicas do músculo esternal descritas, suas origens e inserções, inervação e irrigação sanguínea. Em seguida, foi relatada a importância clínica do conhecimento dessa variação. O músculo esternal apresenta diversas dimensões e inserções, o que dificulta a determinação de sua função. Devido à localização paraesternal, em exames de imagem o referido músculo pode ser visto como uma nodulação anormal na região da mama e ser confundido com um tumor. O reconhecimento dessa variação antes de procedimentos cirúrgicos na parede torácica evita possíveis complicações e possibilita o uso do tecido como retalho muscular em cirurgias reconstrutivas da mama; também pode ser usado na melhora de resultados estéticos em mamoplastia de aumento ou fornecer cobertura extra para próteses. O conhecimento sobre essa variação anatômica é bastante relevante, pois a percepção da existência do músculo esternal e de suas variações relaciona-se a importantes implicações clínicas em cirurgias de mama e tórax.
Conhecimento dos acadêmicos e profissionais da fisioterapia sobre dor: uma revisão sistemática
Authors: Santos Alan Carlos Nery dos , Barbosa Monique Lima , Souza Anelize Gimenez de , Petto Jefferson 
Published: August 2017

Estudos demonstram que acadêmicos e profissionais da fisioterapia apresentam limitações no conhecimento sobre diversos aspectos do tema “dor”. Isso pode implicar em abordagens inadequadas e em maior sofrimento dos pacientes. Assim, objetivou-se revisar estudos que investigaram o conhecimento de acadêmicos e profissionais da fisioterapia sobre dor, bem como os que propuseram estratégias para modificar tal conhecimento. Trata-se de uma revisão sistemática, e foram consultadas as bases de dados EBSCOhost, LILACS, PubMed, REDALYC e SciELO, por meio do cruzamento das palavras-chave: “pain”, “knowledge”, “education”, “curriculum”, “physical therapy specialty” e os seus correspondentes em português. Foram considerados elegíveis os estudos observacionais ou experimentais que analisaram o conhecimento sobre aspectos clínicos, fisiopatológicos e manejo da dor. Também foram elegíveis os que testaram estratégias para modificar o conhecimento sobre dor. A triagem pelos títulos e resumo resultou em 84 estudos. Contudo, apenas cinco foram incluídos. Esses analisaram o conhecimento sobre aspectos gerais da dor, sendo publicados entre 2003 e 2016. Apenas 60% dos estudos investigaram participantes da fisioterapia, sendo que 100% deles verificaram o conhecimento por meio de questionários autoaplicáveis. Quatro estudos utilizaram questionários validados. Somente 20% testaram estratégias para modificar o conhecimento sobre dor. Os resultados desta revisão indicam que o tema “dor” é abordado apenas como subtema complementar, o que, embora permita o aprendizado, não tem sido suficiente para garanti-lo. Profissionais da fisioterapia apresentam inconsistência entre o conhecimento teórico e os seus papeis no manuseio e na assistência humanizada da dor. Estratégias de ensino-aprendizagem ativas podem aprimorar o conhecimento acadêmico sobre dor.
Uso da corrente russa na reabilitação neurológica de paciente com traumatismo crânio encefálico: relato de caso
Authors: Castro Arley Ribeiro de , Angelo Rita di Cássia De Oliveira , Schwingel Paulo Adriano 
Published: August 2017

Introdução: O traumatismo cranioencefálico (TCE) é qualquer agressão capaz de lesão anatômica ou comprometimento funcional do couro cabeludo, crânio, meninges ou encéfalo, que pode causar importantes perdas cognitivas e motoras. Os principais mecanismos de trauma são os acidentes automobilísticos, quedas e as agressões físicas e/ou lesões por arma de fogo. Este estudo objetivou relatar os efeitos de um protocolo de intervenção fisioterapêutica que inclui o uso da Corrente Russa (CR) na reabilitação de um paciente com TCE. Relato de caso: Paciente do sexo masculino, 26 anos, mecânico, etilista crônico, diagnóstico médico de TCE e hemiparesia esquerda desproporcionada com predominância no membro superior, dependente de cadeira de rodas. A avaliação fisioterapêutica foi constituída de aferição de sinais vitais, avaliação dos reflexos superficiais e tendinosos e do tônus muscular, goniometria e teste de força muscular específico. Após avaliação inicial foi aplicado um protocolo de intervenção fisioterapêutico constituído de exercícios terapêuticos e eletroestimulação com CR, com frequência de duas sessões semanais de 50 minutos de duração, por um período de 16 semanas, seguidas de reavaliação. Conclusão: O protocolo de intervenção aplicado contribuiu para a reabilitação funcional do paciente, verificado pelo ganho de amplitude de movimento das articulações do punho, cotovelo, tornozelo e joelho esquerdos; e aumento na graduação de força muscular dos flexores e extensores do punho e do cotovelo, flexores e extensores do joelho e tornozelo esquerdos. Além disso, a deambulação independente foi restituída,com retorno à atividade profissional.
Mobilidade internacional na graduação em medicina: relato de experiência
Authors: Ferreira Iago Gonçalves , Carreira Luciana Brandão , Botelho Nara Macedo 
Published: August 2017

Introdução: A mobilidade acadêmica nas universidades apresenta-se como uma ferramenta para a internacionalização do ensino superior brasileiro, promovendo a inserção dos estudantes universitários em diferentes contextos culturais e educacionais, agregando tanto novos conhecimentos teóricos como habilidades sociais e linguísticas. Relato de experiência: Este artigo trata‑se de um relato de experiência de um estudante de medicina viabilizado pelo programa de mobilidade internacional Ciência Sem Fronteiras, realizado no curso de Promoção da Saúde do Waterford Institute of Technology, na cidade de Waterford, Irlanda, no período de setembro de 2014 a julho de 2015. O relato apresenta as atividades acadêmicas desenvolvidas na instituição, bem como analisa a contribuição dos programas de intercâmbio para a graduação médica. Conclusão: A mobilidade internacional pode representar um importante instrumento para a formação médica, pois estimula o amadurecimento profissional e pessoal dos estudantes, ao expô‑los a um cenário diferenciado, no qual são incitados a refletir sobre suas práticas e seu conhecimento, ao se deparar com o novo e o diferente. Tais contribuições podem representar o aprimoramento das habilidades médicas e humanísticas dos graduandos, configurando-se como um avanço para o ensino médico no Brasi.
Osteopathic Manipulative Treatment to Manage Ophthalmic Conditions
Authors: Sherman Tatyana , Qureshi Yasmin , Bach Austin 
Published: August 2017

Abstract
Although there is little evidence-based literature regarding osteopathic manipulative treatment for ophthalmic conditions, the general principles and techniques of osteopathic manipulative medicine can be used to manage various ophthalmic pathologic conditions. Additional research to support these treatment options and evaluate the role of OMT as a potential conservative treatment option used by ophthalmologists is needed.
DOSCHEDA: a web application for interactive chemoproteomics data analysis
Authors: Contrino Bruno , Miele Eric , Tomlinson Ronald , Castaldi M. Paola , Ricchiuto Piero 
Published: August 2017

BackgroundMass Spectrometry (MS) based chemoproteomics has recently become a main tool to identify and quantify cellular target protein interactions with ligands/drugs in drug discovery. The complexity associated with these new types of data requires scientists with a limited computational background to perform systematic data quality controls as well as to visualize the results derived from the analysis to enable rapid decision making. To date, there are no readily accessible platforms specifically designed for chemoproteomics data analysis.ResultsWe developed a Shiny-based web application named DOSCHEDA (Down Stream Chemoproteomics Data Analysis) to assess the quality of chemoproteomics experiments, to filter peptide intensities based on linear correlations between replicates, and to perform statistical analysis based on the experimental design. In order to increase its accessibility, DOSCHEDA is designed to be used with minimal user input and it does not require programming knowledge. Typical inputs can be protein fold changes or peptide intensities obtained from Proteome Discover, MaxQuant or other similar software. DOSCHEDA aggregates results from bioinformatics analyses performed on the input dataset into a dynamic interface, it encompasses interactive graphics and enables customized output reports.ConclusionsDOSCHEDA is implemented entirely in R language. It can be launched by any system with R installed, including Windows, Mac OS and Linux distributions. DOSCHEDA is hosted on a shiny-server athttps://doscheda.shinyapps.io/doschedaand is also available as a Bioconductor package (http://www.bioconductor.org/).