bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship Between Self‐Blame for the Onset of a Chronic Physical Health Condition and Emotional Distress: A Systematic Literature Review
Authors: Callebaut Leah , Molyneux Philip , Alexander Tim 
Published: December 2016

ObjectivePast literature presents contrasting perspectives regarding the potential influence of self‐blame on adjustment to illness. This systematic literature review aimed to summarize findings from all investigations to date that have explored the relationship between self‐blame for the onset of a chronic physical health condition and emotional distress.MethodBetween November 2014 and February 2015, electronic databases were searched for relevant literature. Only those studies which assessed self‐blame directly and related specifically to illness onset were included within the review. The methodological and reporting quality of all eligible articles was assessed, and themes within the findings were discussed using a narrative synthesis approach.ResultsThe majority of studies found self‐blame to be associated with increased distress. However, several concerns with the quality of the reviewed articles may undermine the validity of their conclusions.ConclusionsIt is important for professionals supporting people with chronic physical health conditions to have an understanding of how of self‐critical causal attributions might relate to emotional distress. Further research is required to understand the concept of self‐blame, the factors that may encourage this belief and to develop reliable and valid measures of this experience. Copyright © 2016 John Wiley & Sons, Ltd.Key Practitioner MessageWhat does this study add?

The review presents an exploration of the role of self‐blame in emotional adjustment following the diagnosis of a chronic physical health condition.
This is the first review to synthesize findings from studies measuring self‐blame beliefs directly and specifically for illness onset and their relationship to indicators of distress and wellbeing.
Findings suggest that self‐blame for illness onset is often associated with emotional distress for people with cancer, HIV/AIDS and cardiovascular disease. This has implications for how healthcare professionals respond to self‐blaming beliefs in the context of illness.
Research quality concerns are identified for many of the reviewed studies, highlighting a need for further research on this topic.
The Chemical Route to a Carbon Dioxide Neutral World
Authors: Martens Johan A. , Bogaerts Annemie , De Kimpe Norbert , Jacobs Pierre A. , Marin Guy B. , Rabaey Korneel , Saeys Mark , Verhelst Sebastian 
Published: December 2016

AbstractExcessive CO2 emissions in the atmosphere from anthropogenic activity can be divided into point sources and diffuse sources. The capture of CO2 from flue gases of large industrial installations and its conversion into fuels and chemicals with fast catalytic processes seems technically possible. Some emerging technologies are already being demonstrated on an industrial scale. Others are still being tested on a laboratory or pilot scale. These emerging chemical technologies can be implemented in a time window ranging from 5 to 20 years. The massive amounts of energy needed for capturing processes and the conversion of CO2 should come from low‐carbon energy sources, such as tidal, geothermal, and nuclear energy, but also, mainly, from the sun. Synthetic methane gas that can be formed from CO2 and hydrogen gas is an attractive renewable energy carrier with an existing distribution system. Methanol offers advantages as a liquid fuel and is also a building block for the chemical industry. CO2 emissions from diffuse sources is a difficult problem to solve, particularly for CO2 emissions from road, water, and air transport, but steady progress in the development of technology for capturing CO2 from air is being made. It is impossible to ban carbon from the entire energy supply of mankind with the current technological knowledge, but a transition to a mixed carbon–hydrogen economy can reduce net CO2 emissions and ultimately lead to a CO2‐neutral world.
Relationship of fast‐scale and slow‐scale instabilities in switching circuit with multiple inputs
Authors: Asahara Hiroyuki , Banerjee Soumitro , Kousaka Takuji 
Published: December 2016

SummaryPower converter circuits, such as current‐controlled or voltage‐controlled converters and inverters often have multiple inputs in the controller. The multiple inputs cause high‐frequency and low‐frequency oscillations. In earlier studies, the characteristics of circuits in fast‐scale and slow‐scale dynamics have been investigated. However, in many cases, circuits with multiple inputs have three or more dimensional topology which makes detailed analysis difficult. In this paper, we analyze a simple interrupted electric circuit in order to understand essential characteristics of fast‐scale and slow‐scale dynamics. The advantage of this simple interrupted circuit is that it is possible to derive a 1‐dimensional map, which facilitates rigorous studies. Based on the structure of the return map and the characteristic multiplier, we explain the characteristics of the system. We report the occurrence of pitchfork, period doubling, and border collision bifurcations in slow scale, and period doubling bifurcation in fast scale. We found that local bifurcation, which appears in fast‐scale dynamics, does not significantly affect the global behavior of the system while instabilities in the slow‐scale dynamics strongly affect the system behavior. Copyright © 2016 John Wiley & Sons, Ltd.
Nanoparticle silver coexposure reduces the accumulation of weathered persistent pesticides by earthworms
Authors: Mukherjee Arnab , Hawthorne Joseph , White Jason C. , Kelsey Jason W. 
Published: December 2016

Abstract

Although the use of engineered nanomaterials continues to increase, how these materials interact with coexisting contaminants in the environment is largely unknown. The effect of silver (Ag) in bulk, ionic, and nanoparticle (NP; bare and polyvinyl pyrrolidone–coated) forms at 3 concentrations (0 mg/kg, 500 mg/kg, 1000 mg/kg, 2000 mg/kg; ion at 69 mg/kg, 138 mg/kg, 276 mg/kg) on the accumulation of field-weathered chlordane and dichlorodiphenyldichloroethylene + metabolites (DDX) by Eisenia fetida (earthworm) was investigated. Earthworm biomass and survival were unaffected by treatment. At the 500 mg/kg and 1000 mg/kg exposure levels, NP-exposed earthworms contained significantly greater Ag (194–245%) than did the bulk exposed organisms; NP size or coating had no impact on element content. Generally, exposure to Ag of any type or at any concentration significantly reduced pesticide accumulation, although reductions for DDX (35.1%; 8.9–47.0%) were more modest than those for chlordane (79.0%; 17.4–92.9%). For DDX, the reduction in pesticide accumulation was not significantly affected by Ag type or concentration. For chlordane, the 3 NP exposures suppressed chlordane accumulation significantly more than did bulk exposure; earthworms exposed to bulk Ag contained 1170 ng/g chlordane, but levels in the NP-exposed earthworms were 279 ng/g. At the 500 mg/kg exposure, the smallest coated NPs exerted the greatest suppression in chlordane accumulation; at the 2 higher concentrations, chlordane uptake was unaffected by NP size or coating. The findings show that in exposed earthworms Ag particle size does significantly impact accumulation of the element itself, as well as that of coexisting weathered pesticides. The implications of these findings with regard to NP exposure and risk are unknown but are the topic of current investigation. Environ Toxicol Chem 2017;36:1864–1871. © 2016 SETAC
A method to account for the effect of hydrodynamics on polar organic compound uptake by passive samplers
Authors: Booij Kees , Maarsen Natasja L. , Theeuwen Matthijs , van Bommel Ronald 
Published: December 2016

Abstract

Mass transfer coefficients of the water boundary layer (kw) were measured using alabaster dissolution kinetics in a diffusion cell that was operated at stirring rates between 90 min−1 and 600 min−1, aiming to provide a more robust characterization of the effect of hydrodynamics on the uptake of polar compounds by passive samplers, as compared with characterizations in terms of stirring rates and water flow velocities. The measured kw helped to quantitatively understand calcium sulfate transport through a poly(ethersulfone) membrane and 2 water boundary layers (at both sides of the membrane). Alabaster-based kw value were used to understand atrazine transport in the diffusion cell, allowing the conclusion that atrazine transport in the membrane is via the pore space, rather than via the polymer matrix. The merits of measuring alabaster dissolution rates for passive sampler calibration and application in the field are discussed. The authors propose that passive sampler calibrations be carried out under controlled kw conditions, rather than under controlled stirring rates or flow velocities. This would facilitate the interpretation of passive sampler calibration studies and the translation of laboratory-based water sampling rates to flow conditions that apply in the field. Environ Toxicol Chem 2017;36:1517–1524. © 2016 SETAC
Development of assessment toolkits for improving the diagnosis of the Lewy body dementias: feasibility study within the DIAMOND Lewy study
Authors: Thomas Alan J. , Taylor John Paul , McKeith Ian , Bamford Claire , Burn David , Allan Louise , O'Brien John 
Published: December 2016

ObjectiveThe Lewy body dementias (LBD, dementia with Lewy bodies and Parkinson's disease dementia) are the second most common cause of neurodegenerative dementia but remain under‐recognised, with long delays from initial assessment to diagnosis. Whilst validated instruments have been developed for key symptoms, there is no brief instrument for overall diagnostic assessment suitable for routine practice. We here report the development of such assessment toolkits.MethodsWe developed the LBD assessment toolkits in three stages. First, we conducted a systematic search for brief validated assessments for key symptoms and combined these into draft instruments. Second, we obtained feedback on acceptability and feasibility through two rounds of interviews with our patient and public involvement group. This led to modification of the toolkits. Finally, we piloted the toolkits in a feasibility study in routine dementia and Parkinson's disease services to produce final instruments suitable for routine clinical practice.ResultsEleven clinicians, working in both dementia/memory assessment and Parkinson's disease/movement disorder services, consented to pilot the assessment toolkits and provide feedback on their feasibility. Clinicians worked in routine health service (not academic) settings and piloted the draft toolkits by integrating them into their regular clinical assessments. Feedback obtained informally, by written comments and through qualitative interviews led to modifications and production of final acceptable versions.ConclusionsWe were able to address an important need, the under‐diagnosis of LBD, by developing toolkits for improving the recognition and diagnosis of the LBD, which were acceptable to clinicians working in routine dementia and Parkinson's disease services. © 2016 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons, Ltd.
Entropy Analysis of a Coupled‐Convection Flow through a Vertical Channel Partially Filled by a Porous Medium with Injection/Suction and Slip Boundary Conditions
Authors: Chauhan Dileep Singh , Khemchandani Vinita 
Published: December 2016

AbstractFlow fields, thermal fields, and entropy generation have been investigated for fully developed mixed convection flow between two vertical porous plates. The vertical channel is partially filled by a porous medium, and channel walls are subjected to a constant injection velocity at the left wall and constant suction velocity at the right wall. The viscous dissipation effects and velocity slip for the longitudinal component of the velocity at the channel walls are also taken into account. The momentum and energy equations for the mixed convection problem in the vertical channel are solved by means of the perturbation series method, by taking perturbation parameter proportional to the Brinkman number. For the present problem, numerical solution is also obtained and compared with the analytical solution. The effects of various pertinent parameters on the velocity distribution, temperature distribution, entropy generation rate, and Bejan number are investigated and discussed graphically.
Association between overall rate of change in rising breath alcohol concentration and the magnitude of acute tolerance of subjective intoxication via the Mellanby method
Authors: Morris David H. , Amlung Michael T. , Tsai Chia‐Lin , McCarthy Denis M. 
Published: December 2016

AbstractObjectiveThe magnitude of acute tolerance is a strong predictor of the development of longer‐term chronic tolerance and plays a decisive role in risky decisions (e.g., driving after drinking). Therefore, it is important to identify factors that increase the magnitude of this adaptive process. This study explored whether acute tolerance magnitude varied as a function of the overall rate of increase in breath alcohol concentration (BrAC).MethodsTwenty‐nine young adult social drinkers (M age = 22.55, SD = 3.10; 62.1% women) consumed a moderate dose of alcohol (men: 0.86 g/kg, women: 0.75 g/kg) in a controlled laboratory setting. Subjective intoxication was assessed at matched BrACs (~0.060 g/dl) on each limb of the BrAC curve.ResultsHierarchical regression results indicated that faster overall increases in BrAC on the ascending limb were associated with greater acute tolerance for subjective intoxication ratings (p < .01, R2 = .29).ConclusionsThese results present some of the first evidence that faster increases in BrAC may be associated with greater acute tolerance, as indicated by greater reduction in subjective intoxication across the limbs of the BrAC curve. This greater reduction may, in turn, promote heavier drinking and/or engagement in behaviors for which one is unfit (e.g., driving after drinking).
Population Pharmacokinetics and Exposure–Response Relationship of Carfilzomib in Patients With Multiple Myeloma
Authors: Ou Ying , Doshi Sameer , Nguyen Anh , Jonsson Fredrik , Aggarwal Sanjay , Rajangam Kanya , Dimopoulos Meletios A. , Stewart A. Keith , Badros Ashraf , Papadopoulos Kyriakos P. , Siegel David , Jagannath Sundar , Vij Ravi , Niesvizky Ruben , Graham Richard , Visich Jenn 
Published: December 2016

AbstractA population pharmacokinetic (PK) model and exposure–response (E‐R) analysis was developed using data collected from 5 phase 1b/2 and 2 phase 3 studies in subjects with multiple myeloma. Subjects receiving intravenous infusion on 2 consecutive days each week for 3 weeks (days 1, 2, 8, 9, 15, and 16) in each cycle at doses ranging from 15 to 20/56 mg/m2 (20 mg/m2 in cycle 1 and, if tolerated, escalated to 56 mg/m2 on day 8 of cycle 1). The population PK analysis indicated that among all the covariates tested, the only statistically significant covariate was body surface area on carfilzomib clearance; however, this covariate was unlikely to be clinically significant. Despite inclusion of different populations (relapsed or relapsed/refractory), treatments (carfilzomib monotherapy or combination therapy), infusion lengths (2 to 10 minutes or 30 minutes), and different doses, the E‐R analysis of efficacy showed that after adjusting for baseline characteristics, higher area under the concentration–time curve was associated with improved overall response rate (ORR), from 15 to 20/56 mg/m2. No positive relationships between maximum concentration and ORR were identified, indicating that ORR would not be expected to be impacted by infusion length. For safety end points, no statistically significant relationship between exposure and increasing risk of adverse events was identified. The results of an E‐R analysis provided strong support for a carfilzomib dose at 20/56 mg/m2 as a 30‐minute infusion for monotherapy and combination therapy. This article illustrates an example of application of E‐R analysis to support labeling dose recommendation in the absence of extensive clinical data.
Impact of everolimus on Japanese patients with advanced pancreatic neuroendocrine neoplasms
Authors: Lee Lingaku , Ito Tetsuhide , Igarashi Hisato , Ueda Keijiro , Fujiyama Takashi , Kawabe Ken , Ogawa Yoshihiro 
Published: December 2016

AbstractBackgroundAlthough everolimus has become a key therapeutic agent in patients with advanced pancreatic neuroendocrine neoplasms (PNEN), its efficacy and safety in clinical practice remains unclear.MethodsForty‐seven patients with advanced PNEN treated with everolimus were reviewed retrospectively. To evaluate the safety of everolimus as a long‐term treatment, the patients were divided into two groups according to treatment duration: group A, ≤1 year (n = 21); group B, >1 year (n = 26).ResultsAmong 42 patients with pancreatic neuroendocrine tumors (PNET), the median progression‐free survival, overall survival, and objective response rate were 27.5 months, 60.8 months, and 19.0%, respectively. Two patients with pancreatic neuroendocrine carcinomas (PNEC) with lower Ki‐67 index and well‐differentiated tumors showed favorable responses. More patients in group A discontinued everolimus owing to adverse drug reactions (ADRs) than in group B. The median relative dose intensity was significantly lower in group B than group A (P = 0.045), whereas the drug interruption rate was significantly higher in group B than group A (P < 0.001).ConclusionsEverolimus showed significant clinical benefit in Japanese patients with advanced PNEN. Prevention of severe ADRs by appropriate dose reduction and interruption is necessary for a long‐term continuation of everolimus.
Sucrose replacement in high ratio white layer cakes
Authors: Miller Rebecca A , Dann Orelia E , Oakley Amanda R , Angermayer Megan E , Brackebusch Katherine H 
Published: December 2016

AbstractBACKGROUNDSeveral commercially available alternative sweeteners have potential in reducing the caloric content of baked products. Sugar alcohols and natural sweeteners have similar bulk as sucrose and can replace sucrose directly. High intensity sweeteners have high potency but light weight so bulking agents are often added. This study determined alternative sweeteners and combinations of alternative sweetener and a bulking agent that produced good quality white layer cakes.RESULTSCakes made with maltitol were acceptable but erythritol and fructose produced undesirable cakes. Maltodextrin and polydextrose were acceptable bulking agents, producing cakes that were similar to control cakes. The flavor of cakes sweetened with sucralose was acceptable but those with stevia had a disagreeable metallic aftertaste. Cakes made with sucralose plus maltodextrin were preferred over those containing sucralose plus polydextrose. Consumer acceptance of flavor, texture and overall liking of cakes containing maltitol was similar to sucrose and both were preferred over cakes containing maltodextrin plus sucralose.CONCLUSIONReplacing sucrose with maltitol in white layer cakes reduced the caloric content by 16% with no loss in quality. © 2016 Society of Chemical Industry
Microwave enhanced oxidation treatment of organic fertilizers
Authors: More Abhilasha , Srinivasan Asha , Liao Ping Huang , Lo Kwang Victor 
Published: December 2016

AbstractBACKGROUNDLiquid organic fertilizers (LOFs) are relatively easier to degrade than those of solid organic fertilizers, and the nutrients are readily available for plant uptake. Microwave enhanced advanced oxidation treatment (MW/H2O2‐AOP) was used to convert solid organic fertilizers (insoluble blood meal, bone meal, feather meal, sunflower ash and a mixture) into LOF.RESULTSAfter the MW/H2O2‐AOP treatment, high soluble nitrogen (11–29%), soluble phosphorus (64%) and potassium (92%), as well as low total suspended solids content could be obtained. The resulting LOF would make the nutrients more bioavailable, and would provide some of them for the plant uptake immediately. Temperature and hydrogen peroxide dosage were found to be significant factors affecting nitrogen release from blood meal and feather meal, while temperature and pH were found to be significant factors for solubilizing phosphorus and potassium from bone meal and ash, respectively.CONCLUSIONThe MW/H2O2‐AOP reduced suspended solids, and released nutrients into solution; therefore, it was an effective treatment method to make LOFs. © 2016 Society of Chemical Industry
On the Early Irrigation of Gypseous Lands in Spain
Authors: Herrero Juan 
Published: December 2016

AbstractGypseous lands occur mainly in arid regions of the world, where irrigation is required for profitable agriculture. The study of gypseous soils has been neglected for years in the main stream of the soil science. Agriculture and, more recently, the environmental concerns are challenging research in the countries that have extensive gypsum outcrops. Those challenges have been obvious since at least the 1960s, when economic development in some of these countries led to the construction of new irrigation schemes and associated infrastructures. This paper presents examples of documents about agriculture on gypseous soils in Spain that might be applicable to similar situations elsewhere in the world. Copyright © 2016 John Wiley & Sons, Ltd.
Separating pathways in double‐quantum optical spectroscopy reveals excitonic interactions
Authors: Tollerud Jonathan O. , Davis Jeffrey A. 
Published: December 2016

AbstractTechniques for coherent multidimensional optical spectroscopy have been developed and utilised to understand many different processes, including energy transfer in photosynthesis and many‐body effects in semiconductor nanostructures. Double‐quantum 2D spectroscopy is one variation that has been particularly useful for understanding many‐body effects. In condensed matter systems, however, there are often many competing signal pathways, which can make it difficult to isolate different contributions and retrieve quantitative information. Here, a means of separating overlapping pathways while maintaining the fidelity of the relevant peak/s is demonstrated. This selective approach is used to isolate the double‐quantum signal from a mixed two exciton state in a semiconductor quantum well. The removal of overlapping peaks allows analysis of the relevant peak‐shape and thus details of interactions with the environment and other carriers to be revealed. An alternative pulse ordering identifies a double‐quantum state associated only with GaAs defects, the signature of which has previously been confused with other interaction induced effects. The experimental approach described here provides access to otherwise hidden details of excitonic interactions and demonstrates that the manner in which the double‐quantum coherence is generated can be important and provide an additional control to help understand the many‐body physics in complex systems.
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Solution form of a higher‐order system of difference equations and dynamical behavior of its special case
Authors: Haddad Nabila , Touafek Nouressadat , Rabago Julius Fergy T. 
Published: December 2016

The solution form of the system of nonlinear difference equations

urn:x-wiley:mma:media:mma4248:mma4248-math-0001
where the coefficients a,b,α,β and the initial values x − i,y − i,i∈{0,1,…,k} are non‐zero real numbers, is obtained. Furthermore, the behavior of solutions of the aforementioned system when p = 1 is examined. Copyright © 2016 John Wiley & Sons, Ltd.