bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between High Endocardial Unipolar Voltage and Improved Left Ventricular Function in Patients with Ischemic Cardiomyopathy
Authors: Park Ki , Lai Dejian , Handberg Eileen M. , Moyé Lem , Perin Emerson C. , Pepine Carl J. , Anderson R. David 
Published: August 2016

We know that endocardial mapping reports left ventricular electrical activity (voltage) and that these data can predict outcomes in patients undergoing traditional revascularization. Because the mapping data from experimental models have also been linked with myocardial viability, we hypothesized an association between increased unipolar voltage in patients undergoing intramyocardial injections and their subsequent improvement in left ventricular performance.
For this exploratory analysis, we evaluated 86 patients with left ventricular dysfunction, heart-failure symptoms, possible angina, and no revascularization options, who were undergoing endocardial mapping. Fifty-seven patients received bone marrow mononuclear cell (BMC) injections and 29 patients received cell-free injections of a placebo.
The average mapping site voltage was 9.7 ± 2 mV, and sites with voltage of ≥6.9 mV were engaged by needle and injected (with BMC or placebo). For all patients, at 6 months, left ventricular ejection fraction (LVEF) improved, and after covariate adjustment this improvement was best predicted by injection-site voltage. For every 2-mV increase in baseline voltage, we detected a 1.3 increase in absolute LVEF units for all patients (P=0.038). Multiple linear regression analyses confirmed that voltage and the CD34+ count present in bone marrow (but not treatment assignment) were associated with improved LVEF (P=0.03 and P=0.014, respectively).
In an exploratory analysis, higher endocardial voltage and bone marrow CD34+ levels were associated with improved left ventricular function among ischemic cardiomyopathy patients. Intramyocardial needle injections, possibly through stimulation of angiogenesis, might serve as a future therapy in patients with reduced left ventricular function and warrants investigation.
Right Ventricular Enlargement within Months of Arteriovenous Fistula Creation in 2 Hemodialysis Patients
Authors: Ragupathi Loheetha , Johnson Drew , Marhefka Gregary D. 
Published: August 2016

Surgically created arteriovenous fistulae (AVF) for hemodialysis can contribute to hemodynamic changes. We describe the cases of 2 male patients in whom new right ventricular enlargement developed after an AVF was created for hemodialysis. Patient 1 sustained high-output heart failure solely attributable to the AVF. After AVF banding and subsequent ligation, his heart failure and right ventricular enlargement resolved. In Patient 2, the AVF contributed to new-onset right ventricular enlargement, heart failure, and ascites. His severe pulmonary hypertension was caused by diastolic heart failure, diabetes mellitus, and obstructive sleep apnea. His right ventricular enlargement and heart failure symptoms did not improve after AVF ligation.
We think that our report is the first to specifically correlate the echocardiographic finding of right ventricular enlargement with AVF sequelae. Clinicians who treat end-stage renal disease patients should be aware of this potential sequela of AVF creation, particularly in the upper arm. We recommend obtaining preoperative echocardiograms in all patients who will undergo upper-arm AVF creation, so that comparisons can be made postoperatively. Alternative consideration should be given to creating the AVF in the radial artery, because of less shunting and therefore less potential for right-sided heart failure and pulmonary hypertension. A multidisciplinary approach is optimal when selecting patients for AVF banding or ligation.
Giant Right Coronary Artery Aneurysm Associated with a Fistula Draining into the Superior Vena Cava
Authors: Dolapoglu Ahmet , Ott David A. 
Published: August 2016

Giant coronary artery aneurysm associated with a coronary–cameral fistula is an uncommon condition. Such aneurysms are usually associated with other cardiac diseases, such as coronary atherosclerosis, and therefore might augment myocardial ischemia in adults. The main indications for surgical intervention are severe coexisting coronary artery disease, evidence of embolization, and aneurysmal enlargement or rupture.
We describe a large right coronary artery aneurysm and a coronary–cameral fistula that drained into the superior vena cava. The surgical repair was successful.
CONVERSAÇÕES ENTRE ARTES E CIÊNCIAS SOCIAIS NOS LIMITES DO CONTEMPORÂNEO
Authors: Fletcher John , Pacheco Agenor Sarraf , Chaves Ernani Pinheiro 
Published: August 2016

Este estudo visa analisar diálogos recentes e, muitas vezes, divergentes entre as artes visuais e as ciências sociais, de maneira a ajudar na compreensão de nosso presente conflituoso e polifônico. Os diálogos em questão problematizam operações estéticas de sociedades complexas, bem como encaram diferentes experiências como parte de um conjunto de histórias interligadas e sobrepostas, cada uma das quais com seu próprioprograma e ritmo de desenvolvimento, todos coexistindo e interagindo entre si. Com o intuito de traçar, longe de um colecionismo de materiais heterogêneos, uma descrição analítica e reflexão interpretativa, o presente trabalho busca encadeamentos teóricos a partir de intelectuais da filosofia e sociologia Pós-Modernas, da antropologia Pós-Moderna do seminário de Santa Fé e das premissas Pós-Colonial e Descolonial. Com um aporte de autores como Fredric Jameson, Jean Baudrillard, James Clifford, Homi Babha, Edward Said, Walter Mignolo, Adolfo Alban, Joaquín Barriendos, entre outros, visamos reiterar, portanto, uma agendainterpretativa destituída dos processos de colonização do poder, do ser, do ouvir, do fazer e do ver para se pensar artes visuais em sociedades periféricas globais.Palavras-Chave: Arte, cultura, regimes visuais, etnografia do pensamento.
A LITERATURA LATINO- AMERICANA E AS ALEGORIAS NACIONAIS DE “CONCIERTO BARROCO”
Authors: CAIXETA Maryllú de Oliveira 
Published: August 2016

A identidade problemática da América Latina reflete-se na recorrência do tema na literatura realizada nessa parte do continente. As imagens de Caliban, do antropófago e a atribuição de um sentido barroco à experiência latino- americana caracterizam uma parte expressiva da literatura em questão. O “Concierto Barroco” de Carpentier exemplifica, por meio do personagem Amo, as dificuldades da elite crioula em encontrar uma origem nobre para si na Europa de seus avós e mesmo de identificar-se com ela. O personagem escravo músico Filomeno naturaliza a fabulação, assim como o Amo, e transita abusadamente entre as hierarquias, alegorizando o sentido barroco da identidade em questão. O jazz é o produto crioulo, antropofágico e barroco de negros cuja origem apagada na história foi substituída pela fabulação nos spiritual, num caminho musical que renovou a música moderna no mundo todo. É significativo que Carpentier tenha criado por meio de Filomeno a unidade da experiência americana, cuja fronteira é o México. PALAVRAS- CHAVE: barroco; antropofagia. Literatura latino- americana.
VANGUARDA REVOLUCIONÁRIA E INDIGENISMO DESDE O PONTO DE VISTA COSMOPOLITA DE CÉSAR VALLEJO
Authors: SOUZA Carla Damêane Pereira de 
Published: August 2016

Esta pesquisa foi feita com a intenção de dinamizar a interpretação do tema Ibndigenismo em algumas obras de César Vallejo (1892-1938), desde o seu ponto de vista cosmopolita enfatizando a estreita relação que o unia ao seu contemporâneo José Carlos Mariátegui (1894- 1930). Frente às chamadas Vanguardas do século XX, apontar a proposta do Amauta no Peru como um movimento comprometido em unir as ideologias políticas e estéticas que eventualmente estão incorporadas na poética de Vallejo durante os anos em que viveu em Paris.PALAVRAS- CHAVE: Poesia; Vanguarda; Identidade Cultural; Política.
A CRISE DE SENTIDO E A GLOBALIZAÇÃO CONTRA- HEGEMÔNICA NA LITERATURA DE LÍNGUA PORTUGUESA
Authors: RIBEIRO Giselle Rodrigues 
Published: August 2016

Cada vez mais se evidencia uma grande crise de sentido no mundo predominantemente capitalizado em que vivemos. Não obstante, podemos já perceber uma reação a este respeito. Trata-se do fenômeno da globalização contra- hegemônica, conforme este conceito é delineado por Boaventura de Sousa Santos em A globalização e as Ciências Sociais. Neste texto, objetivamos, então, pontuar como esta tendência apresenta-se já idealizada e presente na tessitura literária em língua portuguesa. Para tanto, consideramos duas obras de amplitude bem distintas, são elas Ensaio sobre a cegueira, do português José Saramago e Místida, de Abdulai Sila, escritor da Guiné- Bissau, livro este de que examinamos o primeiro capítulo, embora muitas das considerações a se realizar estejam relacionadas a toda a composição. Além disso, é necessário pensar que antes de adentrarmos a abordagem da própria ação de resistência que configura a globalização contra- hegemônica é preciso por em evidencia contra o quê determinados grupos se insurgem. Este é, portanto, o procedimento que seguimos nesta exposição.PALAVRAS- CHAVE: Globalização contra- hegemônica; literaturas de língua portuguesa; resistência; literaturas da Guiné-Bissau.
A TRANSMIDIALIDADE COMO ESTRATÉGIA DISCURSIVA
Authors: Sousa Silvia Maria de 
Published: August 2016

O trabalho discute, à luz da semiótica do discurso, os conceitos de transmidiação e intermidialidade, buscando descrever estratégias enunciativas e modos de interação derivados da “convergência” (JENKINS, 2008) entre TV e internet. Elege-se como objeto de investigação telenovelas da Rede Globo e conteúdos a elas relacionados, disponibilizados no portal GShow (http://gshow.globo.com). A partir da formulação de uma “semiótica das práticas” (FONTANILLE, 2005; 2008), as denominadas narrativas transmidiáticas são tomadas como textos construídos em face da congregação de diferentes mídias: TV, computador, celular, livro, e-book, câmera fotográfica etc. Postula-se que esses textos condensam diferentes práticas semióticas e se expandem por meio de estratégias que envolvem múltiplas plataformas.
Risk of Cause-Specific Death in Individuals With Diabetes: A Competing Risks Analysis
Authors: Baena-Díez Jose Miguel , Peñafiel Judit , Subirana Isaac , Ramos Rafel , Elosua Roberto , Marín-Ibañez Alejandro , Guembe María Jesús , Rigo Fernando , Tormo-Díaz María José , Moreno-Iribas Conchi , Cabré Joan Josep , Segura Antonio , García-Lareo Manel , Gómez de la Cámara Agustín , Lapetra José , Quesada Miquel , Marrugat Jaume , Medrano Maria José , Berjón Jesús , Frontera Guiem , Gavrila Diana , Barricarte Aurelio , Basora Josep , García Jose María , Pavone Natalia C. , Lora-Pablos David , Mayoral Eduardo , Franch Josep , Mata Manel , Castell Conxa , Frances Albert , Grau María ,   on behalf of the FRESCO Investigators
Published: August 2016

OBJECTIVE
Diabetes is a common cause of shortened life expectancy. We aimed to assess the association between diabetes and cause-specific death.

RESEARCH DESIGN AND METHODS
We used the pooled analysis of individual data from 12 Spanish population cohorts with 10-year follow-up. Participants had no previous history of cardiovascular diseases and were 35–79 years old. Diabetes status was self-reported or defined as glycemia &gt;125 mg/dL at baseline. Vital status and causes of death were ascertained by medical records review and linkage with the official death registry. The hazard ratios and cumulative mortality function were assessed with two approaches, with and without competing risks: proportional subdistribution hazard (PSH) and cause-specific hazard (CSH), respectively. Multivariate analyses were fitted for cardiovascular, cancer, and noncardiovascular noncancer deaths.

RESULTS
We included 55,292 individuals (15.6% with diabetes and overall mortality of 9.1%). The adjusted hazard ratios showed that diabetes increased mortality risk: 1) cardiovascular death, CSH = 2.03 (95% CI 1.63–2.52) and PSH = 1.99 (1.60–2.49) in men; and CSH = 2.28 (1.75–2.97) and PSH = 2.23 (1.70–2.91) in women; 2) cancer death, CSH = 1.37 (1.13–1.67) and PSH = 1.35 (1.10–1.65) in men; and CSH = 1.68 (1.29–2.20) and PSH = 1.66 (1.25–2.19) in women; and 3) noncardiovascular noncancer death, CSH = 1.53 (1.23–1.91) and PSH = 1.50 (1.20–1.89) in men; and CSH = 1.89 (1.43–2.48) and PSH = 1.84 (1.39–2.45) in women. In all instances, the cumulative mortality function was significantly higher in individuals with diabetes.

CONCLUSIONS
Diabetes is associated with premature death from cardiovascular disease, cancer, and noncardiovascular noncancer causes. The use of CSH and PSH provides a comprehensive view of mortality dynamics in a population with diabetes.
Efficacy and Safety of Liraglutide Added to Capped Insulin Treatment in Subjects With Type 1 Diabetes: The ADJUNCT TWO Randomized Trial
Authors: Ahrén Bo , Hirsch Irl B. , Pieber Thomas R. , Mathieu Chantal , Gómez-Peralta Fernando , Hansen Troels Krarup , Philotheou Areti , Birch Sune , Christiansen Erik , Jensen Thomas Jon , Buse John B. ,   for the ADJUNCT TWO Investigators
Published: August 2016

OBJECTIVE
To investigate the efficacy and safety of liraglutide added to capped insulin doses in subjects with type 1 diabetes.

RESEARCH DESIGN AND METHODS
A 26-week, placebo-controlled, double-blind, parallel-group trial enrolling 835 subjects randomized 3:1 receiving once-daily subcutaneous liraglutide (1.8, 1.2, and 0.6 mg) or placebo added to an individually capped total daily dose of insulin.

RESULTS
Mean baseline glycated hemoglobin (HbA1c) (8.1% [65.0 mmol/mol]) was significantly decreased with liraglutide versus placebo at week 26 (1.8 mg: –0.33% [3.6 mmol/mol]; 1.2 mg: –0.22% [2.4 mmol/mol]; 0.6 mg: –0.23% [2.5 mmol/mol]; placebo: 0.01% [0.1 mmol/mol]). Liraglutide significantly reduced mean body weight (–5.1, –4.0, and –2.5 kg for 1.8, 1.2, and 0.6 mg, respectively) versus placebo (–0.2 kg). Significant reductions in daily insulin dose and increases in quality of life were seen with liraglutide versus placebo. There were higher rates of symptomatic hypoglycemia (21.3 vs. 16.6 events/patient/year; P = 0.03) with liraglutide 1.2 mg vs. placebo and of hyperglycemia with ketosis &gt;1.5 mmol/L with liraglutide 1.8 mg vs. placebo (0.5 vs. 0.1 events/patient/year; P = 0.01).

CONCLUSIONS
In a broad population of subjects with long-standing type 1 diabetes, liraglutide added to capped insulin reduced HbA1c, body weight, and insulin requirements but with higher rates of hypoglycemia for liraglutide 1.2 mg and hyperglycemia with ketosis for liraglutide 1.8 mg.
Predictors of 30-day readmission after aneurysmal subarachnoid hemorrhage: a case-control study
Authors: Greenberg Jacob K. , Guniganti Ridhima , Arias Eric J. , Desai Kshitij , Washington Chad W. , Yan Yan , Weng Hua , Xiong Chengjie , Fondahn Emily , Cross DeWitte T. , Moran Christopher J. , Rich Keith M. , Chicoine Michael R. , Dhar Rajat , Dacey Ralph G. , Derdeyn Colin P. , Zipfel Gregory J. 
Published: August 2016

OBJECTIVEDespite persisting questions regarding its appropriateness, 30-day readmission is an increasingly common quality metric used to influence hospital compensation in the United States. However, there is currently insufficient evidence to identify which patients are at highest risk for readmission after aneurysmal subarachnoid hemorrhage (SAH). The objective of this study was to identify predictors of 30-day readmission after SAH, to focus preventative efforts, and to provide guidance to funding agencies seeking to risk-adjust comparisons among hospitals.METHODSThe authors performed a case-control study of 30-day readmission among aneurysmal SAH patients treated at a single center between 2003 and 2013. To control for geographic distance from the hospital and year of treatment, the authors randomly matched each case (30-day readmission) with approximately 2 SAH controls (no readmission) based on home ZIP code and treatment year. They evaluated variables related to patient demographics, socioeconomic characteristics, comorbidities, presentation severity (e.g., Hunt and Hess grade), and clinical course (e.g., need for gastrostomy or tracheostomy, length of stay). Conditional logistic regression was used to identify significant predictors, accounting for the matched design of the study.RESULTSAmong 82 SAH patients with unplanned 30-day readmission, the authors matched 78 patients with 153 nonreadmitted controls. Age, demographics, and socioeconomic factors were not associated with readmission. In univariate analysis, multiple variables were significantly associated with readmission, including Hunt and Hess grade (OR 3.0 for Grade IV/V vs I/II), need for gastrostomy placement (OR 2.0), length of hospital stay (OR 1.03 per day), discharge disposition (OR 3.2 for skilled nursing vs other disposition), and Charlson Comorbidity Index (OR 2.3 for score ≥ 2 vs 0). However, the only significant predictor in the multivariate analysis was discharge to a skilled nursing facility (OR 3.2), and the final model was sensitive to criteria used to enter and retain variables. Furthermore, despite the significant association between discharge disposition and readmission, less than 25% of readmitted patients were discharged to a skilled nursing facility.CONCLUSIONSAlthough discharge disposition remained significant in multivariate analysis, most routinely collected variables appeared to be weak independent predictors of 30-day readmission after SAH. Consequently, hospitals interested in decreasing readmission rates may consider multifaceted, cost-efficient interventions that can be broadly applied to most if not all SAH patients.
Nerve transfers for restoration of finger flexion in patients with tetraplegia
Authors: Bertelli Jayme A. , Ghizoni Marcos F. 
Published: August 2016

OBJECTIVE
The purpose of this paper was to report the authors' results with finger flexion restoration by nerve transfer in patients with tetraplegia.

METHODS
Surgery was performed for restoration of finger flexion in 17 upper limbs of 9 patients (8 male and 1 female) at a mean of 7.6 months (SD 4 months) after cervical spinal cord injury. The patients' mean age at the time of surgery was 28 years (SD 15 years). The motor level according to the ASIA (American Spinal Injury Association) classification was C-5 in 4 upper limbs, C-6 in 10, and C-7 in 3.
In 3 upper limbs, the nerve to the brachialis was transferred to the anterior interosseous nerve (AIN), which was separated from the median nerve from the antecubital fossa to the midarm. In 5 upper limbs, the nerve to the brachialis was transferred to median nerve motor fascicles innervating finger flexion muscles in the midarm. In 4 upper limbs, the nerve to the brachioradialis was transferred to the AIN. In the remaining 5 upper limbs, the nerve to the extensor carpi radialis brevis (ECRB) was transferred to the AIN. Patients were followed for an average of 16 months (SD 6 months). At the final evaluation the range of finger flexion and strength were estimated by manual muscle testing according to the British Medical Research Council scale.

RESULTS
Restoration of finger flexion was observed in 4 of 8 upper limbs in which the nerve to the brachialis was used as a donor. The range of motion was incomplete in all 5 of these limbs, and the strength was M3 in 3 limbs and M4 in 1 limb. Proximal retrograde dissection of the AIN was associated with better outcomes than transfer of the nerve to the brachialis to median nerve motor fascicles in the arm. After the nerve to the brachioradialis was transferred to the AIN, incomplete finger flexion with M4 strength was restored in 1 limb; the remaining 3 limbs did not show any recovery. Full finger flexion with M4 strength was demonstrated in all 5 upper limbs in which the nerve to the ECRB was transferred to the AIN. No functional downgrading of elbow flexion or wrist extension strength was observed.

CONCLUSIONS
In patients with tetraplegia, finger flexion can be restored by nerve transfer. Nerve transfer using the nerve to the ECRB as the donor nerve produced better recovery of finger flexion in comparison with nerve transfer using the nerve to the brachialis or brachioradialis.
Automated analysis of security protocols with global state
Authors: Kremer Steve , Künnemann Robert 
Published: August 2016

Security APIs, key servers and protocols that need to keep the status of transactions, require to maintain a global, non-monotonic state, e.g., in the form of a database or register. However, most existing automated verification tools do not support the analysis of such stateful security protocols – sometimes because of fundamental reasons, such as the encoding of the protocol as Horn clauses, which are inherently monotonic. A notable exception is the recent tamarin prover which allows specifying protocols as multiset rewrite (msr) rules, a formalism expressive enough to encode state. As multiset rewriting is a “low-level” specification language with no direct support for concurrent message passing, encoding protocols correctly is a difficult and error-prone process. We propose a process calculus which is a variant of the applied pi calculus with constructs for manipulation of a global state by processes running in parallel. We show that this language can be translated to msr rules whilst preserving all security properties expressible in a dedicated first-order logic for security properties. The translation has been implemented in a prototype tool which uses the tamarin prover as a backend. We apply the tool to several case studies among which a simplified fragment of PKCS#11, the Yubikey security token, and an optimistic contract signing protocol.
Development of SSR markers for the genus Patellifolia (Chenopodiaceae)
Authors: Nachtigall Marion , Bülow Lorenz , Schubert Jörg , Frese Lothar 
Published: August 2016

Premise of the study:Microsatellite primers were developed to promote studies on the patterns of genetic diversity within Patellifolia patellaris (Chenopodiaceae) and the relationship between the three species of the genus Patellifolia.Methods and Results:The genomic sequence from P. procumbens was screened for simple sequence repeats (SSRs), and 3648 SSRs were identified. A subset of 53 SSR markers was validated, of which 25 proved to be polymorphic in the three species except for the P. webbiana–specific marker JKIPat16. The number of alleles ranged from 85 in P. patellaris, 187 in P. procumbens, and 202 in P. webbiana.Conclusions:The set of 25 new markers will facilitate studies of the relationships between the three Patellifolia species and of the spatial and temporal distribution of genetic diversity within the species.
Impact des évolutions démographiques sur l'épargne et les marchés financiers
Authors: d’Albis Hippolyte 
Published: August 2016

Dans cet article, l'hypothèse d' asset meltdown , qui anticipe une forte baisse des prix des actifs causée par le passage à la retraite des cohortes nombreuses du baby boom est discutée. Dans un premier temps, la corrélation entre variables financières et démographiques est présentée, ainsi que les principaux arguments théoriques qui soutiennent l'hypothèse. Dans un second temps, il est démontré que ces arguments résistent difficilement à une analyse poussée. En particulier, les effets globaux du passage à la retraite des baby boomers sur l'épargne et les prix de marché laissent penser que l'épargne totale des ménages ne devrait pas diminuer dans les prochaines années et que le lien entre les variables démographiques et les prix de marché est difficile à établir. Si l'hypothèse d' asset meltdown ne semble pas robuste, la prise en compte des variables démographiques permet néanmoins de mieux comprendre les dynamiques des variables financières. Classification JEL : G10, J10.