bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global epidemiology and socioeconomic correlates of hypopharyngeal cancer in 2020 and its projection to 2040: findings from GLOBOCAN 2020
Authors: Mousavi Seyed Ehsan , Ilaghi Mehran , Mirzazadeh Yasaman , Mosavi Jarrahi Alireza , Nejadghaderi Seyed Aria 
Published: September 2024

BackgroundHypopharyngeal cancer (HC) comprises less than 5% of all malignant tumors in the head and neck. They often present at an advanced stage, thereby resulting in high mortalities. We aimed to report the epidemiology of HC globally, regionally, and nationally by age, sex, and socioeconomic status in 2020 and its projection to 2040.MethodsData on HC incidence and mortality were extracted from the GLOBOCAN 2020. Age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and mortality-to-incidence ratios (MIRs) were calculated. We used bivariate correlation test, presenting results through Pearson’s correlation coefficient (r) to investigate the correlation between the metrics, human development index (HDI), and current healthcare expenditure (CHE) as a percentage of gross domestic product (GDP) (CHE/GDP).ResultsIn 2020, there were 84254 new HC cases globally (ASIR: 0.91 per 100000). Moreover, HC resulted in 38599 mortalities in 2020 (ASMR: 0.41). Furthermore, the global MIR of HC was 0.45. The ASIR and ASMR of HC were higher in men than women. Also, HDI demonstrated significant correlations with HC ASIR (r= 0.249, p&lt;0.01), ASMR (r= 0.185, p&lt;0.05), and MIR (r= -0.449, p&lt;0.001). Moreover, a weak significant correlation was also observed between CHE/GDP and MIR (r= -0.295, p&lt;0.001). The number of new HC cases and mortalities were estimated to increase by 50% and 55% in 2040, respectively.ConclusionHC is a relatively rare cancer but with a substantial sex and geographic divide in distribution. Key priorities should thus include establishing high-quality cancer registries worldwide.
Research hotspots and future trends in lipid metabolism in chronic kidney disease: a bibliometric and visualization analysis from 2004 to 2023
Authors: Wang Ying , Liu Tongtong , Liu Weijing , Zhao Hailing , Li Ping 
Published: September 2024

BackgroundDisorders of lipid metabolism play a key role in the initiation and progression of chronic kidney disease (CKD). Recently, research on lipid metabolism in CKD has rapidly increased worldwide. However, comprehensive bibliometric analyses in this field are lacking. Therefore, this study aimed to evaluate publications in the field of lipid metabolism in CKD over the past 20 years based on bibliometric analysis methods to understand the important achievements, popular research topics, and emerging thematic trends.MethodsLiterature on lipid metabolism in CKD, published between 2004 and 2023, was retrieved from the Web of Science Core Collection. The VOSviewer (v.1.6.19), CiteSpace (v.6.3 R1), R language (v.4.3.2), and Bibliometrix (v.4.1.4) packages (https://www.bibliometrix.org) were used for the bibliometric analysis and visualization. Annual output, author, country, institution, journal, cited literature, co-cited literature, and keywords were also included. The citation frequency and H-index were used to evaluate quality and influence.ResultsIn total, 1,285 publications in the field of lipid metabolism in CKD were identified in this study. A total of 7,615 authors from 1,885 institutions in 69 countries and regions published articles in 466 journals. Among them, China was the most productive (368 articles), and the United States had the most citations (17,880 times) and the highest H-index (75). Vaziri Nosratola D, Levi Moshe, Fornoni Alessia, Zhao Yingyong, and Merscher Sandra emerged as core authors. Levi Moshe (2,247 times) and Vaziri Nosratola D (1,969 times) were also authors of the top two most cited publications. The International Journal of Molecular Sciences and Kidney International are the most published and cited journals in this field, respectively. Cardiovascular disease (CVD) and diabetic kidney disease (DKD) have attracted significant attention in the field of lipid metabolism. Oxidative stress, inflammation, insulin resistance, autophagy, and cell death are the key research topics in this field.ConclusionThrough bibliometric analysis, the current status and global trends in lipid metabolism in CKD were demonstrated. CVD and DKD are closely associated with the lipid metabolism of patients with CKD. Future studies should focus on effective CKD treatments using lipid-lowering targets.
Effect of Parenting Style, attachment to parents and self-compassion on the occurrence and recovery motivation for non-suicidal self-injury in adolescents
Authors: Liu Pei , Liu Jianbo , Li Yi , Lu Jianping 
Published: September 2024

BackgroundNon-suicidal self-injury (NSSI) is a worldwide mental health problem that deserves thorough investigation. This study aims to explore the effect of parenting styles, attachment to parents, and self-compassion on the occurrence of non-suicidal self-injury (NSSI) behavior in adolescents and whether these factors influence their recovery motivation.MethodsA total of 132 adolescents who had engaged in NSSI within the last year and 72 adolescents who had never engaged in NSSI were recruited from the Shenzhen Kangning Hospital and from primary and secondary schools and communities. Differences in the Hamilton Depression Scale (HAMD), Inventory of Parent and Peer Attachment (IPPA), Egma Minn av. Bardndosnauppforstran (EMBU), and Self-Compassion Scale (SCS) of participants were compared. A binary logistic model was established to measure the odds ratios of these variables on the occurrence of NSSI. In the NSSI adolescent sample, separate binary logistic models were created with NSSI impulse inhibition, NSSI resistance activity, and NSSI recovery motivation as dependent variables and with parenting styles, attachment to parents, and self-compassion as independent variables.ResultsCompared with adolescents with no NSSI behavior, those who had engaged in NSSI within the past year had higher scores on the HAMD, as well as higher EMBU-negative father parental behavior (punishment, excessive interference, rejection, and overprotection), EMBU-negative mother parental behavior (excessive interference, rejection, and punishment), and SCS negative self-compassion scores. Moreover, adolescents with NSSI had lower EMBU-father emotional warmth, EMBU-mother emotional warmth, IPPA-attachment to father, IPPA-attachment to mother, and SCS positive self-compassion scores. Current depressive symptoms and maternal punishment are risk factors for NSSI in adolescents, while positive self-compassion was a protective factor. Positive self-compassion can positively predict NSSI impulse inhibition, NSSI resistance activity, and NSSI recovery motivation. However, we unexpectedly found that the father’s emotional warmth negatively predicts NSSI resistance activity.ConclusionThis study found that positive self-compassion has a significant impact on the prevention of and recovery from NSSI behavior in adolescents.
Negative impact of online gambling problematic in disabled and non-disabled university students: exploring the risk profile
Authors: Suriá-Martínez Raquel , García-Castillo Fernando , Villegas-Castrillo Esther , López-Sánchez Carmen , Carretón-Ballester Carmen 
Published: September 2024

IntroductionThe rise of online gambling has brought about significant concerns, particularly regarding its impact on university students. This issue becomes even more complex when considering students with disabilities.ObjectivesThis research examines the gambling profile and beliefs of university students based on whether they have a disability. In turn, it seeks to identify if there is a typology of at-risk gamblers according to the disability variable. Finally, it aims to find out the prevalence of gambling among students depending on whether they have a disability and the typology of at-risk gambler.MethodA total of 704 university students (135 with disabilities and 569 without disabilities) completed the NODS Belief Questionnaire to assess problems associated with gambling and to generate a typological grouping of risk gamblers, as well as a questionnaire designed specifically for the gambler profile.ResultsIt was found that a small percentage of participants engage in gambling on a daily basis, with a higher frequency among students with disabilities. In addition, it was observed that the behavior and concern about financial expenditure on gambling interferes with their daily activities and is a cause for concern, with higher risk being observed to a greater extent in students with disabilities.DiscussionThese data suggest the importance for universities and relevant authorities to address these problems comprehensively, providing adequate resources for students with disabilities and promoting a culture of wellbeing that discourages problematic gambling activities and encourages healthy alternatives for entertainment and stress management.
Unveiling the burden of COPD: perspectives on a patient-reported outcome measure to support communication in outpatient consultations—an interview study among patients
Authors: Gronhaug Louise Muxoll , Farver-Vestergaard Ingeborg , Frølund Jannie Christina , Lindström Egholm Cecilie , Ottesen Anders Løkke 
Published: September 2024

IntroductionChronic Obstructive Pulmonary Disease (COPD) profoundly affects physical, psychological, and social aspects of life, yet these issues often remain unaddressed. Patient-Reported Outcomes Measures (PROM) have the potential to address these issues by promoting person-centered communication. However, their impact in COPD practice remains uncertain. This study aimed to investigate how patients with COPD perceive the usefulness of a new holistic PROM for general palliative care (PRO-Pall) before and during outpatient consultations.MethodsSemi-structured telephone interviews were conducted with patients diagnosed with moderate to very severe COPD, 2-5 days after consultation at a respiratory outpatient clinic in Denmark. Interviews were transcribed verbatim and analyzed inductively using qualitative content analysis.ResultsNine patients (five males; mean age: 66 years) participated in the study with four themes emerging: (1) Unlocking thoughts: Completing PRO-Pall stimulated patients’ self-reflection, which revealed previously overlooked COPD-related issues, particularly psychosocial challenges. (2) Unmasking concerns: Patients felt encouraged to be honest, rather than concealing their concerns. (3) Breaking the ice: PRO-Pall responses enabled direct questioning by healthcare professionals during consultations, initiating discussions on patients’ sensitive yet vital COPD-related matters. (4) Deepening the dialogue: Healthcare professionals’ targeted and attentive approach fostered more holistic and meaningful discussions, providing most patients with a deeper understanding of psychosocial issues affecting their well-being.ConclusionCompleting PRO-Pall prior to outpatient consultations prompted most patients with COPD to unveil previously unacknowledged psychosocial challenges. During consultations, addressing these challenges initiated open discussions on individual concerns, enhancing most patients’ understanding of the multifaceted burden of COPD.
Insights into the Metabolite Profiles of Two Camellia (Theaceae) Species in Yunnan Province through Metabolomic and Transcriptomic Analysis
Authors: Niu Miao , Li Ranyang , Li Xiongyu , Yang Hongyan , Ding Jianliang , Zhou Xianxiu , He Yuqi , Xu Yawen , Qu Qian , Liu Zhiwei , Li Jiahua 
Published: September 2024

Tea (Camellia sinensis) falls into the family Theaceae, is a valuable commercial crop, and tea products made from its buds and young leaves are favored by consumers all over the world. The more common Thea plant is Camellia sinensis (C. sinensis), but its most important relative, Camellia taliensis (C. taliensis), is also utilized by locals in the area of cultivation to manufacture tea. In this investigation, C. taliensis (DL) and C. sinensis (QJZ) were characterized in terms of their agronomic traits, physicochemical indices, metabolomics, and transcriptomics. The leaf area of DL is larger than that of QJZ; the color of DL’s buds and leaves is yellowish-green, while that of QJZ’s is green. DL’s buds and leaves are more densely velvety than those of QJZ. The HPLC results indicated that the physicochemical contents varied considerably between the two samples, with DL having greater concentrations of EGCG and GABA than QJZ, while QJZ had remarkably higher concentrations of C, CA, and EGC than DL. A total of 2269 metabolites and 362,190,414 genes were positively identified, with the number of DAMs and DEGs being 1001 and 34,026, respectively. The flavonoids, phenolic acids, and alkaloid metabolites were dramatically different between the two tea group plants. Bioinformatics profiling revealed that the DAMs and DEGs of the two tea group plants interacted with each other and were involved in metabolic pathways, including “biosynthesis of secondary metabolites”, “biosynthesis of amino acids”, “biosynthesis of cofactors”, “phenylpropanoid biosynthesis”, and “flavonoid biosynthesis”. Overall, these results provide statistical support for germplasm conservation and production for both C. taliensis and C. sinensis.
Phytoseiid Mites: Trees, Ecology and Conservation
Authors: Ozman-Sullivan Sebahat K. , Sullivan Gregory T. , Cakir Seyma , Bas Huseyin , Saglam Damla , Doker Ismail , Tixier Marie-Stephane 
Published: September 2024

The highly variable ’leafscapes’ of plants across the world represent billions of square metres of mite habitat. The phytoseiid mites (Acari: Phytoseiidae), an extremely species-rich group of mostly generalist predators, are providers of ecosystem services for humanity worth many hundreds of millions of dollars annually by helping suppress phytophagous mites and insects in forests, agro-ecosystems, shade-houses and home gardens. In this study, the phytoseiid mite assemblages on the leaves of four species of common tree species, namely oak (Quercus cerris var. cerris), poplar (Populus deltoides, P. nigra) and walnut (Juglans regia), were compared. The three data sets used were generated in three independent seasonal studies in Samsun Province, Türkiye, between 2018 and 2022. In total, mite species in 18 families, including 15 families on walnut, were recorded. Nineteen phytoseiid species in 13 genera, Amblydromalus, Amblyseius, Euseius, Kampimodromus, Neoseiulella, Neoseiulus, Paraseiulus, Phytoseius, Transeius, Typhlodromina, Typhlodromips, Typhlodromus and Typhloseiulus, were collected. Only Eusieus amissibilis was collected from all three tree genera, whereas 14 species were collected from only one tree genus. Shannon diversity and Jaccard similarity indexes were calculated for mite families and phytoseiid genera and species. Potential reasons for the observed differences in the phytoseiid assemblages on the different host trees are explored in depth. In the ‘big picture’, global biodiversity, likely including many undescribed phytoseiid species, is threatened by widespread habitat degradation and destruction, especially in the tropics, and accelerating climate change, and rapidly stopping them is imperative.
Comparative Assessment of the Impact of COVID-19 Lockdown on Air Quality: A Multinational Study of SARS-CoV-2 Hotspots
Authors: Ould Boudia Ahmed , Asheesh Mohamed , Adusei-Mensah Frank , Bounab Yazid 
Published: September 2024

In response to the global COVID-19 pandemic, nations implemented lockdown measures to contain the virus. This study assessed air pollution levels during and after lockdowns, focusing on the following heavily affected locations: Oulu and Helsinki in Finland, Paris in France, Madrid in Spain, Milan in Italy, and Wuhan in China. Air Quality Index (AQI) data from these locations over two years were analyzed to understand the effects of lockdowns. The study compared COVID-19 lockdowns in these six cities with SARS-CoV-2 measurements using statistical methods. Variations in outdoor pollutants were evaluated through tests, revealing significant differences. Parametric analyses and regression were employed to study the impacts of lockdown measures on pollution and their relationships. The study comprehensively analyzed the effects of COVID-19 lockdowns on air quality, identifying differences, quantifying changes, and exploring patterns in each city. Pollutant correlations varied among cities during the lockdowns. Regression analysis highlighted the impact of independent variables on pollutants. Decreases in NO2 were observed in Helsinki, Madrid, Oulu, Paris, and Milan, reflecting reduced traffic and industrial activities. Reductions in PM2.5 and PM10 were noted in these cities and in Wuhan, except for O3 levels, which increased. The reduction in human activities improved air quality, particularly for NO2 and PM10. Regional variations underscore the need for tailored interventions. The study observed a substantial decrease in both PM2.5 and NO2 levels during the COVID-19 lockdowns, indicating a direct correlation between reduced human activities, such as transportation and industrial operations, and improved air quality. This underscores the potential impact of environmental measures and suggests the need for sustainable practices to mitigate urban pollution.
Metode Weight Product Untuk Pemilihan Pestisida Yang Sesuai Dengan Jenis Hamanya
Authors: Lubis FFitri Amelia Sari , Nurcahyo Gunadi Widi , Sovia Rini 
Published: September 2024

Technological developments are now growing rapidly in various fields, including the implementation of technology in everyday life, including the world of business and organizations. Digital technology includes information, computing, communications and connectivity, becoming a key factor for achieving sustainable competitive advantage in various industries. The use of technology also provides benefits such as sales monitoring, business recommendations and better decision making. Decision Support System (DSS) is a system that is deliberately created to assist certain parties in making decisions with quality and objective results, in an effective and efficient way of working, and does not depend solely on subjective decisions or based on wrong parameters. . The Weight Product (WP) method is one of the solution methods in Decision Support Systems. Choosing the best product is an important decision in various aspects of life, from purchasing consumer goods to choosing technology in business. UD. Anugrah Jaya Tani is one of the kiosks in Sayur Mahincat village, Kec. Barumun Selatan, Padang Lawas Regency, which operates in the agricultural sector and sells various types of pesticides, herbicides and fertilizers. Pesticides are chemical substances and other materials used to control various pests. For farmers, the types of pests are mites, pest plants, plant diseases caused by fungi (fungi), bacteria and viruses, nematodes (worms that damage roots), snails, mice, birds and other animals that are considered detrimental. This research aims to determine pesticides that are suitable for the type of pest on plants. The method used is a Decision Support System (DDS), namely Weight Product (WP). The data used is 10 data with 6 predetermined criteria. The results of this research are based on the final value obtained from each alternative, the pesticide with the highest value is considered the best alternative and the result is that Alternative A5 is the best pesticide with the highest value of 0.1396, namely Sidabas. This means that the pesticide is considered to best meet the specified criteria with the weight given.
Characteristics of shungite particles of different fractional composition and design of compositions of particulate-filled polymer composite materials with different types of structures
Authors: Pykhtin A. A. , Simonov-Emelyanov I. D. , Kovaleva A. N. , Tsvetkova K. S. 
Published: September 2024

The paper presents the results of studies of technological properties (bulk and true density, particle size of the general fraction, particle size distribution, packing coefficient and maximum packing degree of filler particles, etc.) of shungite particles of different batches produced by LLC Nadvoitsky TDM Plant LLC (Karelia, RF).For the first time for shungite particles of different sizes the values of packing density (kуп) and maximum content of dispersed phase (φm) in DFPCM were determined, which allows to calculate generalized and reduced structure parameters, to carry out classification by structural principle and to design compositions of high-tech polymer composites with given properties.Practically all possible compositions of DFPCM with shungite particles of different sizes and different types of disperse structure are presented.
THE EXISTENCE OF FILLERS IN CONVERTING THE WRITTEN LANGUAGE TO SPOKEN LANGUAGE
Authors: Sarira Pret , Mahmud Murni , Affandi Akhmad , Burhamzah Muftihaturrahmah 
Published: September 2024

This article investigated and examined filler words' types, functions, and factors in students' speech while converting the written language to spoken language at the English department of Universitas Negeri Makassar in the pedagogy of speaking class.Â Subjects are non-native English speakers but EFL students. This article uses qualitative research techniques. The data were collected from classroom observations, interviews, and transcription. The transcriptions were interpreted and grouped using the theory of Rose (1998). The occurrences of fillers were analyzed by the idea of Clark and Tree (2002), and the causes and function of fillers were analyzed by the theory of Kharismawan (2017) and Duvall et al. (2014). The findings showed that: (1) The students produced lexical and non lexical fillers while converting the written language to spoken language.Â (2) Fillers appear at the beginning, middle, and near or the end of the utterance.Â (3) The findings showed that the students produced fillers as hesitation devices, empathizing devices, mitigating devices, editing terms devices, and time-creating devices. Besides, a word cannot be categorized as a filler if it stands or works as a conjunction in an utterance.Â (4) Lastly, this research found that the filler causes were divided attention, infrequent words, and nervousness.