bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detecting Long-term Balancing Selection using Allele Frequency Correlation
Authors: Siewert Katherine M. , Voight Benjamin F. 
Published: March 2017

AbstractBalancing selection occurs when multiple alleles are maintained in a population, which can result in their preservation over long evolutionary time periods. A characteristic signature of this long-term balancing selection is an excess number of intermediate frequency polymorphisms near the balanced variant. However, the expected distribution of allele frequencies at these loci has not been extensively detailed, and therefore existing summary statistic methods do not explicitly take it into account. Using simulations, we show that new mutations which arise in close proximity to a site targeted by balancing selection accumulate at frequencies nearly identical to that of the balanced allele. In order to scan the genome for balancing selection, we propose a new summary statistic,β, which detects these clusters of alleles at similar frequencies. Simulation studies show that compared to existing summary statistics, our measure has improved power to detect balancing selection, and is reasonably powered in non-equilibrium demographic models or when recombination or mutation rate varies. We computeβon 1000 Genomes Project data to identify lo ci potentially subjected to long-term balancing selection in humans. We report two balanced haplotypes - localized to the genesWFS1andCADM2- that are strongly linked to association signals for complex traits. Our approach is computationally efficient and applicable to species that lack appropriate outgroup sequences, allowing for well-powered analysis of selection in the wide variety of species for which population data are rapidly being generated.
A personalized recommendation model for online apparel shopping based on Kansei engineering
Authors: Zhou Xiaoxi , Liang Hui’e , Dong Zhiya 
Published: March 2017

Purpose
Today clothing has become the largest category in online shopping in China, and even in Asia-Pacific. The satisfaction degree of apparel online shopping can be improved by effective personalized recommendation. The purpose of this paper is to propose a personalized recommendation model and algorithm based on Kansei engineering, traditional filtering algorithm and the knowledge relating to apparel.

Design/methodology/approach
Users’ perceptual image and the design elements of apparel based on Kansei engineering are discussed to build the mapping relation between the design elements and user ratings employing verbal protocol, semantic differential and partial least squares. The implicit knowledge and emotional needs pertaining to users are accessed using analytic hierarchy process. A personalized recommendation model for apparel online shopping is established and the algorithm for the personalized recommendation process is proposed. To present the personalized recommendation model, men’s plaid shirts are taken as the example, and the recommendations of apparel for online shopping were implemented and ranked in the context of differing users’ emotional needs. A comparison between the traditional model and this model is made to verify the effectiveness.

Findings
The recommendation model is capable of analyzing data and information effectively, and providing fast, personalized apparel recommendation services in accordance with users’ emotional needs. The experimental results suggest that the model is effective.

Originality/value
Similar researches of recommendation mainly focus on the field of computer science, the basic idea of which is using users’ history accessing records or the preferences of other similar users for determination of users’ preferences. Since the attributes of apparel products are not factored in the approach referred above, the issue of personalized recommendation cannot be solved in a really effective way. Combining Kansei engineering and recommendation algorithm, a framework for apparel product recommendation is presented and it is a new way for improvement of recommendations for apparel products on shopping sites.
Share more, drive less: Millennials value perception and behavioral intent in using collaborative consumption services
Authors: Hwang Jiyoung , Griffiths Merlyn A. 
Published: March 2017

Purpose
This paper aims to investigate how the cognitive value perceptions and affective attitudes of Millennial consumers are related to behavioral intent in the context of collaborative consumption and how such relationships may be moderated.

Design/methodology/approach
Two scenario-based online studies were conducted with young consumers concerning several collaborative consumption services.

Findings
Using structural equation modeling, the authors found that specific dimensions of value perceptions (utilitarian, hedonic and symbolic) have differing effects on young consumers’ attitude and empathy toward collaborative consumption services. The analysis shows no moderating effects for perceived consumer effectiveness (Study 1 and Study 2) but a significant moderating effect for consumer innovativeness (Study 2).

Research limitations/implications
This research identifies important factors for the attitudinal and behavioral outcome of young consumers, an important consumer group for the emerging trend of collaborative consumption. Also, the role of empathy and two personal traits offer insights.

Practical implications
Substantively, the findings guide marketers in the sharing economy in elevating their strategic tactics and effective approaches to reach this important consumer group.

Originality/value
Given the paucity of research on consumer groups in this context, the current research breaks new ground by investigating value perceptions and empathy as drivers of positive reactions and moderating factors within the collaborative economy.
When organisational effectiveness fails
Authors: Fischbacher-Smith Denis 
Published: March 2017

Purpose
The purpose of this paper is to consider the nature of the business continuity management (BCM) process and to frame it within wider literature on the performance of socio-technical systems. Despite the growth in BCM activities in organisations, some questions remain as to whether academic research has helped to drive this process. The paper seeks to stimulate discussion within this journal of the interplay between organisational performance and BCM and to frame it within the context of the potential tensions between effectiveness and efficiency.

Design/methodology/approach
The paper considers how BCM is defined within the professional and academic communities that work in the area. It deconstructs these definitions in order to and set out the key elements of BCM that emerge from the definitions and considers how the various elements of BCM can interact with each other in the context of organisational performance.

Findings
The relationships between academic research in the area of crisis management and the practice-based approaches to business continuity remain somewhat disjointed. In addition, recent work in the safety management literature on the relationships between success and failure can be seen to offer some interesting challenges for the practice of business continuity.

Research limitations/implications
The paper integrates work in safety, crisis and risk management with BCM in order to identify the main areas of overlap and synergy between these areas of academic research. By definition, the need for business continuity represents the risks and cost of failure in organisational performance in the absence of continuity. This calls into question the effectiveness of organisational processes around decision making, control, and strategic management. The paper sets out a series of issues that are in need of further research.

Practical implications
The paper draws on some of the practice-based definitions of BCM and highlights the limitations and challenges associated with the construct. The paper sets out challenges for BCM based upon theoretical challenges arising in cognate areas of research. The aim is to ensure that BCM is integrated with emerging concepts in other aspects of the management of uncertainty and to do so in a strategic context.

Originality/value
Academic research on performance reflects both the variety and the multi-disciplinary nature of the issues around measuring and managing performance. Failures in organisational performance have also invariably attracted considerable attention due to the nature of a range of disruptive events. The paper reveals some of the inherent paradoxes that sit at the core of the BCM process and its relationships with organisational performance.
The role of food processing and appropriate storage technologies in ensuring food security and food availability in Africa
Authors: Adeyeye Samuel Ayofemi Olalekan 
Published: March 2017

Purpose
This paper aims to review scientific contributions that are essential to reduce the challenges to food security in Africa through food processing and appropriate storage technologies.

Design/methodology/approach
Several literature studies on the role of food processing and appropriate storage technologies in ensuring food security and food availability in Africa were critically reviewed.

Findings
The study revealed that the world faces multiple challenges to food security including under nutrition and overconsumption, rising food prices, population growth, rapid diet transitions, threats to agricultural production, inefficient production practices and supply chains and declining investment in food system research. Many people lack adequate amounts of foods that are rich in the nutrients needed for a healthy and productive life. According to FAO, 1996, chronic undernutrition affects 43 per cent of the Africa’s population or some 215 million people in sub-Saharan Africa. Food security is highly instrumental to the economic growth and sustainability of any country. The use of simple but effective on- and off-farm storage facilities and agro-processing technology should be promoted to add value to products and increase their shelf-life. The Strategic Grain Reserve Scheme should be modernized, strengthened and upgraded to a National Food Reserve Program, which will enable it to handle all staples and essential food products. This will help in attainment of national food security goal. It is also crucial to promote and develop agro-processing in the various African countries for the evolution of virile agro-allied industries and rural micro-enterprises.

Research limitations/implications
The paper reviewed the role of food processing and appropriate food storage technologies in ensuring food security and availability in Africa. There are insufficient data and information on adoption of new food processing and appropriate storage technologies in Africa. Although, there have been some instances where the introduction of modern techniques has resulted in products rejection by consumers.

Practical implications
The paper helps in reviewing food situation in Africa and how to make food available for the people and Africa food secured.

Social implications
This paper revealed strategies that could be used to improve food security and ensuring food availability in Africa.

Originality/value
This review paper is of value to policymakers, government agencies responsible for food quality control and assurance and consumers to make food available and affordable for the people.
Quality evaluation of mutton nuggets incorporated with optimized level of flaxseed flour
Authors: Kumar Sudheer , Mendiratta S.K. , Agrawal Ravi Kant , Sharma Heena , Kumar RR 
Published: March 2017

PurposeFlaxseed is considered as a source of functional ingredients because it contains alpha-linolenic acid and high amount of dietary fiber which provides potential health benefits. Therefore, this paper aims to evaluate the effect of flaxseed flour on the quality of mutton nuggets.Design/methodology/approachMutton nuggets were incorporated with three different levels of hydrated flaxseed flour (1:1), namely, 4, 8 and 12 per cent to optimize the level of incorporation. Detailed profile analysis was carried out to study various physico-chemical parameters, texture profile analysis and color values in the product with optimum level and compared with control product.FindingsThere was no significant difference (p> 0.05) in sensory attributes of product with 4 and 8 per cent level of incorporation except for binding; however, significantly lower (p< 0.01) scores were observed for 12 per cent incorporation level. On the basis of sensory scores, 8 per cent level of incorporation was adjudged as optimum. Incorporation of flaxseed flour resulted in significantly lower (p< 0.01) moisture content, but higher (p< 0.01) fat and dietary fiber content. Texture profile analysis showed increased hardness of the product but resulted in decreased springiness and chewiness parameters. Incorporation of flaxseed flour significantly increased (p< 0.01) redness and yellowness of the product which improved overall acceptability.Originality/valueThe research work is original.
Two‐stage Keypoint Detection Scheme for Region Duplication Forgery Detection in Digital Images
Authors: Emam Mahmoud , Han Qi , Zhang Hongli 
Published: March 2017

AbstractIn digital image forensics, copy‐move or region duplication forgery detection became a vital research topic recently. Most of the existing keypoint‐based forgery detection methods fail to detect the forgery in the smooth regions, rather than its sensitivity to geometric changes. To solve these problems and detect points which cover all the regions, we proposed two steps for keypoint detection. First, we employed the scale‐invariant feature operator to detect the spatially distributed keypoints from the textured regions. Second, the keypoints from the missing regions are detected using Harris corner detector with nonmaximal suppression to evenly distribute the detected keypoints. To improve the matching performance, local feature points are described using Multi‐support Region Order‐based Gradient Histogram descriptor. Based on precision–recall rates and commonly tested dataset, comprehensive performance evaluation is performed. The results demonstrated that the proposed scheme has better detection and robustness against some geometric transformation attacks compared with state‐of‐the‐art methods.
Next‐Generation Sequencing Analyses of Bacterial Community Structures in Soybean Pastes Produced in Northeast China
Authors: Lee Mi‐Hwa , Li Fan‐Zhu , Lee Jiyeon , Kang Jisu , Lim Seong‐Il , Nam Young‐Do 
Published: March 2017

AbstractFermented soybean foods contain nutritional components including easily digestible peptides, cholesterol‐free oils, minerals, and vitamins. Various fermented soybean foods have been developed and are consumed as flavoring condiments in Asian regions. While the quality of fermented soybean foods is largely affected by microorganisms that participate in the fermentation process, our knowledge about the microorganisms in soybean pastes manufactured in Northeast China is limited. The current study used a culture‐independent barcoded pyrosequencing method targeting hypervariable V1/V2 regions of the 16S rRNA gene to evaluate Korean doenjang and soybean pastes prepared by the Hun Chinese (SPHC) and Korean minority (SPKM) populations in Northeast China. In total, 63399 high‐quality sequences were derived from 16 soybean paste samples collected in Northeast China. Each bacterial species‐level taxon of SPHC, SPKM, and Korean doenjang was clustered separately. Each paste contained representative bacterial species that could be distinguished from each other: Bacillus subtilis in SPKM, Tetragenococcus halophilus in SPHC, and Enterococcus durans in Korean doenjang. This is the 1st massive sequencing‐based study analyzing microbial communities in soybean pastes manufactured in Northeast China, compared to Korean doenjang. Our results clearly showed that each soybean paste contained unique microbial communities that varied depending on the manufacturing process and location.
Simple and Fast Sample Preparation Followed by Gas Chromatography‐Tandem Mass Spectrometry (GC‐MS/MS) for the Analysis of 2‐ and 4‐Methylimidazole in Cola and Dark Beer
Authors: Choi Sol Ji , Jung Mun Yhung 
Published: March 2017

AbstractWe have developed a simple and fast sample preparation technique in combination with a gas chromatography‐tandem mass spectrometry (GC‐MS/MS) for the quantification of 2‐methylimidazole (2‐MeI) and 4‐methylimidazole (4‐MeI) in colas and dark beers. Conventional sample preparation technique for GC‐MS requires laborious and time‐consuming steps consisting of sample concentration, pH adjustment, ion pair extraction, centrifugation, back‐extraction, centrifugation, derivatization, and extraction. Our sample preparation technique consists of only 2 steps (in situ derivation and extraction) which requires less than 3 min. This method provided high linearity, low limit of detection and limit of quantification, high recovery, and high intra‐ and interday repeatability. It was found that internal standard method with diluted stable isotope (4‐MeI‐d6) and 2‐ethylimidazole (2‐EI) could not correctly compensate the matrix effects. Thus, standard addition technique was used for the quantification of 2‐ and 4‐MeI. The established method was successfully applied to colas and dark beers for the determination of 2‐MeI and 4‐MeI. The 4‐MeI contents in colas and dark beers ranged from 8 to 319 μg/L and from trace to 417 μg/L, respectively. Small quantity (0 to 8 μg/L) of 2‐MeI was found only in dark beers. The contents of 4‐MeI (22 μg/L) in colas obtained from fast food restaurants were significantly lower than those (177 μg/L) in canned or bottled colas.
Moral Cosmopolitanism and Democratic Values
Authors: Held David , Maffettone Pietro 
Published: March 2017

AbstractIn the past four decades topics related to the moral evaluation of global politics have occupied a central part of the philosophical debate. The first three sections of this essay provide a reconstruction of the defining features of the globalization of politics and of the ways in which the latter have contributed to the increased philosophical attention on the moral aspects of global affairs. In sections four to six, we move to the current debate in global political theory. Moral cosmopolitanism has come to articulate the boundaries of reasonable disagreement in global political theory and has implied a deep form of commitment to basic human rights. However, we argue in section six, agreement on basic human rights has not evolved into widespread convergence on a range of central political concepts such as distributive justice and legitimacy. Against this backdrop, in sections 7 to 10, we move on to consider the role of democracy in global politics. The main conclusion that the essay will put forward is that the complexity of the institutional landscape beyond traditional state borders does not automatically lend itself to the mechanical application of democratic institutional forms, but that democratic values can still play an important role.
Clinicians’ perceptions of women's experiences of endometriosis and of psychosocial care for endometriosis
Authors: Young Kate , Fisher Jane , Kirkman Maggie 
Published: March 2017

BackgroundEndometriosis is a complex, chronic condition with known psychological and social implications for women. Little is known about clinicians’ perceptions of the psychosocial aspects of endometriosis and associated care.AimTo describe clinicians’ perceptions of women's experiences of living with endometriosis and of the provision of psychosocial care for endometriosis.Materials and methodsA qualitative approach was taken using semi‐structured interviews with eight gynaecologists and four general practitioners who provide care to women with endometriosis in Victoria, conducted by telephone and in person from June to December 2014.ResultsClinicians’ perceptions of women's experiences of endometriosis were consistent with those reported by women, particularly when discussing potential infertility. However, less comprehensive descriptions of the effects of endometriosis on women's work and social life and intimate relationships were observed. Some clinicians asserted that endometriosis is caused by poor mental health. General practitioners positioned themselves as best placed to provide psychosocial care to women with endometriosis; gynaecologists suggested various potential providers but rarely themselves. Most clinicians assessed themselves as not being adequately trained to understand and provide care for the psychosocial aspects of endometriosis; half of the gynaecologists did not believe it was necessary for them to do so.ConclusionsThe findings of this research demonstrate clinicians’ need for further support in the provision of psychosocial care for women with endometriosis, potentially through expanded clinical guidelines and professional development opportunities.
Pru p 3, a marker allergen for lipid transfer protein sensitization also in Central Europe
Authors: Mothes‐Luksch N. , Raith M. , Stingl G. , Focke‐Tejkl M. , Razzazi‐Fazeli E. , Zieglmayer R. , Wöhrl S. , Swoboda I. 
Published: March 2017

AbstractIn the Mediterranean area, lipid transfer proteins (LTPs) are important causes of plant‐food allergies often associated with severe allergic reactions. There, peach LTP (Pru p 3) seems to be the primary sensitizer, whereas in Central Europe, little is known about the importance of LTP sensitization. In this region, allergen extract‐based diagnosis is often complicated by co‐sensitization to Bet v 1, the major birch pollen allergen, its cross‐reactive food allergens, and profilins. We investigated the role of LTP sensitization in Central European patients displaying strong allergic reactions to plant‐derived food. Analysis of IgE reactivity revealed that ten of thirteen patients were sensitized to Pru p 3, nine to Bet v 1, and two to profilin. Our results showed that LTP sensitization represents a risk factor for severe allergic symptoms in Central Europe. Furthermore, the strong IgE reactivity detected in immunoblots of plant‐food extracts indicated that Pru p 3 can be used as a marker allergen for LTP sensitization also in Central European patients.