bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modernizing a Major Federal Government Survey: A Review of the Redesign of the Current Population Survey Health Insurance Questions
Authors: Pascale Joanne 
Published: June 2016

Abstract
Measurement error can be very difficult to assess and reduce. While great strides have been made in the field of survey methods research in recent years, many ongoing federal surveys were initiated decades ago, before testing methods were fully developed. However, the longer a survey is in use, the more established the time series becomes, and any change to a questionnaire risks a break in that time series. This article documents how a major federal survey – the health insurance module of the Current Population Survey (CPS) – was redesigned over the course of 15 years through a systematic series of small, iterative tests, both qualitative and quantitative. This overview summarizes those tests and results, and illustrates how particular questionnaire design features were identified as problematic, and how improvements were developed and evaluated. While the particular topic is health insurance, the general approach (a coordinated series of small tests), along with the specific tests and methods employed, are not uniquely applicable to health insurance. Furthermore, the particular questionnaire design features of the CPS health module that were found to be most problematic are used in many other major surveys on a range of topic areas.
Role of mast cells in cow metritis
Authors: Wang Guo-Qing , Hou Jin-Long , Huang Huan-Yu , Yuan Chao-Wen 
Published: June 2016

Abstract

Introduction: Bovine postpartum metritis causes great losses. Mast cell (MC)-released mediators participate in uterine inflammation and immune response, but their role in postpartum metritis in cows has not been reported. This study investigated the effect of endometrial MC on the disorder.

Material and Methods: Ten dairy cows, at 6 to 10 days postpartum and with acute purulent metritis made up the experimental group, and 10 comparable healthy cows the control group. Endometrial histamine and IgE levels were determined by ELISA, and the MC particle state and expression of histamine H1 (H1R) and H2 (H2R) mRNA receptors were examined by transmission electron microscope and real-time quantitative PCR, respectively.

Results: Endometrial histamine and IgE levels were significantly higher in the experimental group. In the control group, homogenously distributed size-varied granules were seen in MC cytoplasm of endometrium of lamina propria. In the experimental group however, these showed degranulation with features of reduction. The level of H1R mRNA was lower in the experimental group, but that of H2R mRNA was higher.

Conclusion: The results suggest MC type I hypersensitivity characteristics during metritis, and histamine provocation of local inflammation. High expression of H2R and low expression of H1R inhibited the inflammatory response and prevented excessive uterine tissue damage.
Impact of early castration and health status on the performance of Holstein-Friesian and beef crossbred calves
Authors: Wielgosz-Groth Zofia , Sobczuk-Szul Monika , Nogalski Zenon , Purwin Cezary , Pogorzelska-Przybyłek Paulina , Winarski Rafał 
Published: June 2016

Abstract

Introduction: This article presents the analysis of the correlation between the category and health status of calves and the results of their rearing and levels of selected blood parameters.

Material and Methods: The study included 105 Polish Holstein-Friesian and beef (Limousine, Charolaise and Hereford) crossbred calves. Young bulls were purchased at the age of two to four weeks. The animals underwent quarantine, were dehorned, and 46 young bulls were castrated. The germ horns were removed by burning out. Castration was carried out with a bloodless method using a rubber band. The calves were kept in groups and fed a milk replacer administered via teats from automated milk-feeding stations. After the period of milk feeding, the calves were fed grass silage ad libitum and a concentrate at 2.5 kg/animal/day. The calves were weighed every two weeks. Blood for analyses was sampled at 43 d of age.

Results: After the rearing period finished at the age of six months, young bulls and steers had similar body weights (176.17 and 176.55 kg) and approximate average daily weight gains from birth (0.756 and 0.767 g/day). The healthy calves at six months of age weighed 180.47 kg, whereas the animals which at least once suffered from some diseases during rearing were lighter by approx. 30 kg (P ≤ 0.01). A statistically significant (P ≤ 0.01) difference was found for the count of red blood cells and white blood cells. In comparison with healthy individuals, the diseased animals had less RBC (8.33 and 9.42 1012/L respectively) and more WBC (27.03 and 12.26 109/L respectively).

Conclusion: Castration of young bulls did not have any impact on the results of rearing and health status of the calves. The magnitude of the analysed parameters depended on the health status of the calves. Thus RBC and WBC parameters may be used to predict the health status of calves during rearing.
Different Boosting Systems and their Control Strategies for a Spark Ignition Internal Combustion Engine
Authors: Bolehovský Ondřej , Macek Jan 
Published: June 2016

Abstract
This research uses 1-D simulation in GT-Power for evaluation of boosting systems for a spark ignition engine. Exhaust gas driven (waste-gated turbocharger) and mechanical driven (Roots blower) boosting systems are assessed in both steady state and transient modes in terms of performance, efficiency, fuel consumption, drivability, energy distribution and other aspects that influence gas exchange phase. Moreover, different boost control strategies, particularly at partial load, are also evaluated. Results of the research are aimed at helping identify an optimal boosting system for standardized or real-world drive cycles.
The variety of methodology in Mirror Therapy practice for improving hand function after stroke
Authors: Radajewska Alina , Opara Józef , Mehlich Krzysztof 
Published: June 2016

Abstract
Many studies have shown that a repeated exercises in the mirror visual feedback and motor imagery conditions may help to restore a lasted hand function in stroke patients. The evidence of effectiveness of mirror therapy is promising but the use of this method varies widely within studies. It has been postulated that there is a need to formulate basic rules of mirror therapy application with respect to different stages of stroke or severity of hand paresis. In this article the review of methodological variability of applying mirror therapy to patients after stroke has been presented. The review highlights the benefit effect of mirror therapy on motor recovery and activities of daily living after stroke.
Diverse properties of the mesothelial cells in health and disease
Authors: Kawanishi Kunio 
Published: June 2016

AbstractMesothelial cells (MCs) form the superficial anatomic layer of serosal membranes, including pleura, pericardium, peritoneum, and the tunica of the reproductive organs. MCs produce a protective, non-adhesive barrier against physical and biochemical damages. MCs express a wide range of phenotypic markers, including vimentin and cytokeratins. MCs play key roles in fluid transport and inflammation, as reflected by the modulation of biochemical markers such as transporters, adhesion molecules, cytokines, growth factors, reactive oxygen species and their scavengers. MCs synthesize extracellular matrix related molecules, and the surface of MC microvilli secretes a highly hydrophilic protective barrier, “glycocalyx”, consisting mainly of glycosaminoglycans. MCs maintain a balance between procoagulant and fibrinolytic activation by producing a whole range of regulators, can synthetize fibrin and therefore form adhesions. Synthesis and recognition of hyaluronan and sialic acids might be a new insight to explain immunoactive and immunoregulatory properties of MCs. Epithelial to mesenchymal transition of MCs may involve serosal repair and remodeling. MCs might also play a role in the development and remodeling of visceral adipose tissue. Taken together, MCs play important roles in health and disease in serosal cavities of the body. The mesothelium is not just a membrane and should be considered as an organ.
Survival outcomes after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis from gastric cancer: a systematic review
Authors: Chia Claramae Shulyn , Seshadri Ramakrishnan Ayloor , Kepenekian Vahan , Vaudoyer Delphine , Passot Guillaume , Glehen Olivier 
Published: June 2016

AbstractBackground: The current treatment of choice for peritoneal carcinomatosis from gastric cancer is systemic chemotherapy. Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is a new aggressive form of loco-regional treatment that is currently being used in pseudomyxoma peritoneii, peritoneal mesothelioma and peritoneal carcinomatosis from colorectal cancer. It is still under investigation for its use in gastric cancer.Methods: The literature between 1970 and 2016 was surveyed systematically through a review of published studies on the treatment outcomes of CRS and HIPEC for peritoneal carcinomatosis from gastric cancer.Results: Seventeen studies were included in this review. The median survival for all patients ranged from 6.6 to 15.8 months. The 5-years overall survival ranged from 6 to 31%. For patients with complete cytoreduction, the median survival was 11.2 to 43.4 months and the 5-years overall survival was 13 % to 23%. Important prognostic factors were found to be a low peritoneal carcarcinomatosis index (PCI) score and the completeness of cytoreduction.Conclusion: The current evidence suggests that CRS and HIPEC has a role to play in the treatment of peritoneal carcinomatosis from gastric cancer. Long term survival has been shown for a select group of patients. However, further studies are needed to validate these results.
The Building of Bell-Towers Added to Romanian Churches
Authors: Abrudan Ioan Ovidiu 
Published: June 2016

Abstract
This paper aims to emphasize a specific aspect in the evolution of the architecture of churches built by Romanian Orthodox or Greek-Catholic communities in the Sibiu region, in the second half of the eighteenth century and during the nineteenth century. More exactly, it is the widespread presence, in the ecclesiastical architecture of that county, and also in other Romanian Transylvanian settings, of the western tower, added to the church, which housed the bells and sometimes even clocks. In most cases, the raising of these towers was entrusted to Saxon masons from Sibiu, whose names have been preserved in inscriptions on the walls of edifices, or by their registering in contracts signed by the Romanians who ordered the execution. The involvement of those worthy craftsmen represented an important factor in maintaining the dialogue and cultural exchanges between the two communities that lived together in the Sibiu County region.
Medieval Liturgical Vestments Depicted in the Iconographic Programs of Southern Transylvanian Churches (14th to 16th centuries)
Authors: Stoia Adrian 
Published: June 2016

Abstract
This work sets out to list and describe the liturgical vestments present in panel and mural paintings of churches located in southern Transylvania. The surviving body of such vestments on display in the ”Brukenthal” National Museum of Sibiu and that of the Black Church of Brașov not only confirms their use in religious services, but also the fact that they served as models for Transylvanian ecclesiastical painting. Of Western derivation, this type of vestment reflects a way of thinking and stands testament to social status or to the different hierarchies within the church. It is, at the same time, an indication of the development of this kind of craft, produced by specialized workshops.
The Ethnic Pluralism of the Nineteenth Century in Transylvania according to the Ecclesiastical Painting of the Grecu Brothers
Authors: Boicu Dragoş 
Published: June 2016

Abstract
Despite the development of the iconographic programs, the frescoes painted by the Grecu brothers remind us not only of the large ensembles beyond the Carpathians in Walachia and Moldova but also other Transylvanian decorations. These frescoes express not only the spirit of the time or the mentality of the community to which they belonged, but they also represented an opportunity to show the painters’ originality and personality, their need for personal affirmation and artistic individuality, connected to a new sensitivity of a given historical context. The representation of the inhabiting nations in Transylvania in the Passion’s Cycle highlights the disadvantaged status of the Romanian people who were oppressed by the privileged nations: by the Habsburg military force, the inequitable judgement of Saxons and the torments inflicted by Hungarians through their policies. All of these recreate mutatis mutandis the dramatic setting in which Christ was crucified.
The Translation of German Hymns into Romanian Between Poetry and Pragmatism
Authors: Rudolf Gerhild Ingrid 
Published: June 2016

Abstract
After centuries of celebrating the divine services only in German language, the Evangelical Church A. C. in Romania (ECR) embarked during the last few decades on the use of a second language within church. The traditional “Evangelical-Saxon” identity of the congregations is undergoing a changing process. Having lost most of its members through emigration, the Evangelical Church A. C. in Romania copes with new social circumstances which have also an effect upon the choice of language. Therefore, in 2007, the ECR published a bilingual (German and Romanian) hymnal. Translating hymns is an intricate endeavour. The practical use of a bilingual hymn-book is challenging as well. The German-Romanian Evangelical hymnal is a witness of how the diaspora church accommodates itself to new linguistic conditions.
“Ὁ Χριστὸς, μυστικῶς ἱερουργούμενος ἐν ταῖς ἁγίαις σκηναῖς” – Fr. Dumitru Staniloae and the Rediscovering and Reinterpreting St. Cyril of Alexandria’s Teaching About the State of Perpetual Sacrifice of Jesus Christ
Authors: Streza Ciprian Ioan 
Published: June 2016

Abstract
Father Dumitru Staniloae’s complex and integral vision on the Holy Liturgy comprises all the dimensions of life in the church; it constitutes the object of this study, which intends to re-interpret, systematize, and evaluate the teaching of St. Cyril of Alexandria concerning the importance of the Eucharistic Synaxis in the life of the Church. The Eucharistic celebration is only the visible dimension of the eternal Liturgy of love within the Holy Trinity, whose Altar, Oblation and High Priest is Jesus Christ, the slain Lamb, who lives in a state of permanent sacrifice, who was incarnate, who died and arose again, and sent His Holy Spirit in the Church, so as to radiate among those who open up to Him in faith, and thus saturate them with the dynamism of His own surrender to the Father.
The Spatio-Temporal Dynamics of the Ciprnik Complex Landslide, Tamar Valley, Julian Alps, Slovenia
Authors: Šmuc Andrej , Janecka Karolina , Lempa Michał , Kaczka Ryszard J. 
Published: June 2016

AbstractMass movements represent important processes that shape relief in Alpine areas. In this article, we present the spatio-temporal dynamics of the Ciprnik landslide (Julian Alps, NW Slovenia) and interpret its triggering and evolution. In the study area, mass movement activity is characterised by two phases: normal deposition on the fluvial fans that dominated up to 2000, and a more active phase related to the triggering of the Ciprnik complex landslide and formation of an additional debris-flow fan. The Ciprnik landslide started as a translational movement over the discontinuity plane that was mobilised into a debris-flow. The triggering and slope failure resulted from a combination of tectonics (i.e. dip-slope position of the strata, and strong fracturing), lithology (alternation of thin beds of carbonates and fine-grained clastics), and accumulation of precipitation. The debris-flow fan remains active and interfingers with adjacent active fluvial fans.
Bringing Science into Fiction
Authors: Haynes Roslynn D. 
Published: June 2016

Abstract
Science and its predecessor, alchemy, have been topics of fiction in the West for over five centuries but until late last century novelists, with few exceptions, condemned science and scientists on social and moral grounds. However, since the 1990s, science has acquired a more benign and humane image, associated with combatting deadly viruses, saving endangered species and communicating the urgency of dealing with climate change. Novelists, too, are increasingly intent on authenticity in presenting scientific research and the motives and moral dilemmas of scientists. Such science novels risk being overloaded with scientific facts and explanations, so the craft of the writer involves integrating the necessary scientific information without damaging the artistic integrity of the work. This paper explores, through interviews with authors and in-depth reading of texts, how the following writers accommodated the science component within the life-world of their narrative and took steps to avoid an ‘information dump’: Rebecca Goldstein (The Mind-Body Problem and Properties of Light), William Boyd (Brazzaville Beach), Simon Mawer (Mendel’s Dwarf), Susan Gaines (Carbon Dreams), Clare Dudman (Wegener’s Jigsaw), Richard Powers (The Echo Maker), Barbara Kingsolver (Flight Behavior), and Pippa Goldschmidt (The Falling Sky).
Acromegaly incidence, prevalence, complications and long-term prognosis: a nationwide cohort study
Authors: Dal Jakob , Feldt-Rasmussen Ulla , Andersen Marianne , Kristensen Lars Ø , Laurberg Peter , Pedersen Lars , Dekkers Olaf M , Sørensen Henrik Toft , Jørgensen Jens Otto L 
Published: June 2016

Design
Valid data on acromegaly incidence, complications and mortality are scarce. The Danish Health Care System enables nationwide studies with complete follow-up and linkage among health-related databases to assess acromegaly incidence, prevalence, complications and mortality in a population-based cohort study.

Method
All incident cases of acromegaly in Denmark (1991–2010) were identified from health registries and validated by chart review. We estimated the annual incidence rate of acromegaly per 106 person-years (py) with 95% confidence intervals (95% CIs). For every patient, 10 persons were sampled from the general population as a comparison cohort. Cox regression and hazard ratios (HRs) with 95% confidence intervals (95% CIs) were used.

Results
Mean age at diagnosis (48.7 years (CI: 95%: 47.2–50.1)) and annual incidence rate (3.8 cases/106 persons (95% CI: 3.6–4.1)) among the 405 cases remained stable. The prevalence in 2010 was 85 cases/106 persons. The patients were at increased risk of diabetes mellitus (HR: 4.0 (95% CI: 2.7–5.8)), heart failure (HR: 2.5 (95% CI: 1.4–4.5)), venous thromboembolism (HR: 2.3 (95% CI: 1.1–5.0)), sleep apnoea (HR: 11.7 (95% CI: 7.0–19.4)) and arthropathy (HR: 2.1 (95% CI: 1.6–2.6)). The complication risk was also increased before the diagnosis of acromegaly. Overall mortality risk was elevated (HR: 1.3 (95% CI: 1.0–1.7)) but uninfluenced by treatment modality.

Conclusion
(i) The incidence rate and age at diagnosis of acromegaly have been stable over decades, and the prevalence is higher than previously reported. (ii) The risk of complications is very high even before the diagnosis. (iii) Mortality risk remains elevated but uninfluenced by mode of treatment.
The Chromatin Remodeling ComponentArid1aIs a Suppressor of Spontaneous Mammary Tumors in Mice
Authors: Kartha Nithya , Shen Lishuang , Maskin Carolyn , Wallace Marsha , Schimenti John C 
Published: June 2016

AbstractHuman cancer genome studies have identified the SWI/SNF chromatin remodeling complex member ARID1A as one of the most frequently altered genes in several tumor types. Its role as an ovarian tumor suppressor has been supported in compound knockout mice. Here, we provide genetic and functional evidence that Arid1a is a bona fide mammary tumor suppressor, using the Chromosome aberrations occurring spontaneously 3 (Chaos3) mouse model of sporadic breast cancer. About 70% of mammary tumors that formed in these mice contained a spontaneous deletion removing all or part of one Arid1a allele. Restoration of Arid1a expression in a Chaos3 mammary tumor line with low Arid1a levels greatly impaired its ability to form tumors following injection into cleared mammary glands, indicating that ARID1A insufficiency is crucial for maintenance of these Trp53-proficient tumors. Transcriptome analysis of tumor cells before and after reintroduction of Arid1a expression revealed alterations in growth signaling and cell-cycle checkpoint pathways, in particular the activation of the TRP53 pathway. Consistent with the latter, Arid1a reexpression in tumor cells led to increased p21 (Cdkn1a) expression and dramatic accumulation of cells in G2 phase of the cell cycle. These results not only provide in vivo evidence for a tumor suppressive and/or maintenance role in breast cancer, but also indicate a potential opportunity for therapeutic intervention in ARID1A-deficient human breast cancer subtypes that retain one intact copy of the gene and also maintain wild-type TRP53 activity.
Systematic Genetic Screen for Transcriptional Regulators of the Candida albicans White-Opaque Switch
Authors: Lohse Matthew B , Ene Iuliana V , Craik Veronica B , Hernday Aaron D , Mancera Eugenio , Morschhäuser Joachim , Bennett Richard J , Johnson Alexander D 
Published: June 2016

Abstract
The human fungal pathogen Candida albicans can reversibly switch between two cell types named “white” and “opaque,” each of which is stable through many cell divisions. These two cell types differ in their ability to mate, their metabolic preferences and their interactions with the mammalian innate immune system. A highly interconnected network of eight transcriptional regulators has been shown to control switching between these two cell types. To identify additional regulators of the switch, we systematically and quantitatively measured white–opaque switching rates of 196 strains, each deleted for a specific transcriptional regulator. We identified 19 new regulators with at least a 10-fold effect on switching rates and an additional 14 new regulators with more subtle effects. To investigate how these regulators affect switching rates, we examined several criteria, including the binding of the eight known regulators of switching to the control region of each new regulatory gene, differential expression of the newly found genes between cell types, and the growth rate of each mutant strain. This study highlights the complexity of the transcriptional network that regulates the white–opaque switch and the extent to which switching is linked to a variety of metabolic processes, including respiration and carbon utilization. In addition to revealing specific insights, the information reported here provides a foundation to understand the highly complex coupling of white–opaque switching to cellular physiology.