Atividade antinociceptiva e anti-inflamatória do extrato hexânico das folhas de Vismia guianensis Aubl. em camundongos
Authors: Nobre Vinicius Ferreira , Almeida Débora Maria Marchesine , Oliveira Addla Thaine Santos , Barboza Ana Caroline Maia , Lucchese Angélica Maria , Rocha Marilene Lopes 
Published: September 2017

<!--[if gte mso 9]><xml> <o:OfficeDocumentSettings> <o:TargetScreenSize>800x600</o:TargetScreenSize> </o:OfficeDocumentSettings> </xml><![endif]--><p><strong>Introdução: </strong>Plantas medicinais são bastante utilizadas no contexto da medicina popular na Bahia. Estas plantas são consideradas medicinais por suas propriedades terapêuticas e são amplamente comercializadas em feiras livres, mercados e usos religiosos diversos. Dentre as quais, <em>Vismia guianensis </em>pertence à família <em>Clusiaceae </em>e se encontra bem distribuída nas regiões Norte e Nordeste do Brasil. Esta planta é conhecida também como lacre ou capianga e utilizada na indústria de corantes e madeira por possuir um látex alaranjado bastante resinoso. <strong>Objetivo: </strong>Avaliar a atividade antinociceptiva e anti-inflamatória do extrato hexânico de <em>Vismia guianensis. </em><strong>Metodologia: </strong>Foi utilizado o extrato hexânico das folhas de <em>Vismia guianensis </em>em modelos de indução algésica em camundongos. Inicialmente, foi realizada uma triagem farmacológica para observar possíveis efeitos da droga sobre o Sistema Nervoso Central dos animais. Em seguida, foram utilizados como modelos de indução algésica o teste de contorções abdominais induzidas por ácido acético e o teste da formalina. <strong>Resultados e Conclusão: </strong>O extrato testado reduziu significativamente as contorções abdominais e o tempo de lambida da pata, demonstrando que possui atividades antinociceptiva e anti-inflamatória.</p><!--[if gte mso 9]><xml> <w:WordDocument> <w:View>Normal</w:View> <w:Zoom>0</w:Zoom> <w:TrackMoves /> <w:TrackFormatting /> <w:HyphenationZone>21</w:HyphenationZone> <w:PunctuationKerning /> <w:ValidateAgainstSchemas /> <w:SaveIfXMLInvalid>false</w:SaveIfXMLInvalid> <w:IgnoreMixedContent>false</w:IgnoreMixedContent> <w:AlwaysShowPlaceholderText>false</w:AlwaysShowPlaceholderText> <w:DoNotPromoteQF /> <w:LidThemeOther>PT-BR</w:LidThemeOther> <w:LidThemeAsian>X-NONE</w:LidThemeAsian> <w:LidThemeComplexScript>X-NONE</w:LidThemeComplexScript> <w:Compatibility> <w:BreakWrappedTables /> <w:SnapToGridInCell /> <w:WrapTextWithPunct /> 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