bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parametric structure optimization of a main rotor blade as an application for FSI analysis in main rotor optimization process
Authors: Kocjan Jakub , Rogólski Robert 
Published: October 2024

Purpose
Modern warfare and modern battlefield are very demanding. The recent conflicts showed that the usage of the helicopters is very limited and only the best constructions are able to provide support for the operations. The purpose of this research is to show the possibilities of new design tool for main rotor aerostructural optimization. It is a next chapter of the research that is aimed at finding new solutions for rotorcraft constructions.

Design/methodology/approach
This work presents a method of preliminary structure optimization of the main rotor blade using parametric modeling. It is the next step in the main rotor optimization studies. It is the next step after preparing the parametric model for the external shape CFD analysis. As a basis for parametric blade structure calculations, the analytical model is provided in this paper. The equations of rigid blade loads and, as a consequence of the strength elements, stresses are shown. The parametric blade modeling is conducted using the Graphic Integrated Programming language. The parametric design method is shown to be used for various blade planform models and different section airfoils. The structure of a blade is generated automatically after the user enters the parameters. The code-inbuilt analysis systems provide a quick inertia examination of the generated geometry, which is the basis for further optimization. The program calculates the blade loads and verifies them with the given material conditions and proposed safety factors. In the analysis, composite materials for the strength elements were proposed.

Findings
The results of this research showed the application of parametrization into the main rotor blade design loop. It was presented that the main rotor blade structure can be enhanced using fluid-structure interaction (FSI) methods. The time saving with the implementation the process into design loop is shown.

Practical implications
This work can be practically used in the main rotor blade design process. It provides the possibilities to check various blade aerodynamic configuration in a structure strength aspect.

Originality/value
To the best of the authors’ knowledge, there were no published research that combines the main rotor FSI analysis. The method, which is presented in the work, provides a new approach to a rotorcraft design. The application of the parametrization and combining it with the FSI method gives a novel solution for helicopters construction enhancement.
The seawall helps but—: using “material registers” to understand coastal infrastructure for disaster risk management in an island community
Authors: Cajilig Pamela Gloria 
Published: October 2024

PurposeThis paper contributes to discourse about complex disasters by applying cultural lenses to the study of coastal infrastructure (such as seawalls and dikes), thus departing from studies that focus on characterising, assessing, and predicting the physical resilience of hard structural forms that dominate knowledge about coastal infrastructure.Design/methodology/approachThis ethnographic study nuances Philippine coastal infrastructure through examining the material registers of a seawall bordering an island inhabited by artisanal fisherfolk. By “material registers”, this research refers to the socially informed ways of regarding and constructing material configurations and how the latter are enacted and resisted. Data collection was accomplished through focus groups with community leaders, on-site and remote interviews with homeowners, and archival research to further understand the spatial and policy context of the structure.FindingsThe discussion focuses on the seawall’s three material registers (protection, fragility, and misrecognition) and reveals how infrastructure built for an island community of fisherfolk simultaneously fulfils, fails, and complicates the promise of disaster resilience.Research limitations/implicationsThis research demonstrates the potential of “material registers”, a term previously used to analyse architecture and housing, to understand the technopolitics of infrastructure and how materially informed tensions between homeowners' and state notions of infrastructure contribute to protracted experiences of disaster and coastal maladaptation.Practical implicationsThis research signposts the need for disaster risk reduction, climate adaptation, and sustainable development policies that legitimize the construction of infrastructure to recognize the latter's relationship and impact on multiple sphere of coastal life, including housing and citizenship implications.Social implicationsThis research highlights how infrastructure for coastal disaster risk management implicates geographically informed power relations within a community fisherfolk and between their “small” island community and more politically and economically dominant groups.Originality/valueWhereas studies of coastal infrastructure are focused on quantitative and predictive research regarding hard structural forms in megacities, this study apprehends disaster complexity through examining the cultural and contested nature of infrastructure for coastal flood management in an island community of fisherfolk.
Phylogenetic relatedness, not geographic origin, shapes traits across ontogenetic stages for common native and exotic plants in subtropical China
Authors: Liu Zhen , Liang Yuming , Wei Chunqiang , Zhu Biao , Chen Wei , Lu Xinmin 
Published: October 2024

Abstract

Functional traits, which shift as a plant develops from seed to adult and may be phylogenetically conserved, are widely acknowledged to be associated with exotic species invasion. However, existing studies comparing functional traits between native and invasive species often focus on a single ontogenetic stage, yielding mixed results. It remains unclear whether the functional trait differences and their relationship with invasiveness (e.g. range size) of exotic species remain consistent across ontogenetic stages.

In this study, we experimentally compared 18 traits across the seed, early growth and adult stages of 127 native and exotic species from 19 families. These species are common and often co‐occur in the subtropical region of China. We also explored the linkage between these traits, alongside their phylogenetic relatedness with native species and exotic species' range size in China.

Our results show that only seed mass differed between native and exotic species. Moreover, the compositions of traits across all stages and the entire lifespan were primarily influenced by phylogenetic relatedness rather than geographic origin. Further, the range size of exotic species in China positively correlated with their mean phylogenetic distance to native species, with no association with individual functional traits or functional distinctiveness.

Synthesis. Our results emphasize the importance of comparing functional traits across ontogenetic stages between native and exotic species to improve our understanding of the role of functional traits in shaping plant invasion. Our findings also underscore the pivotal role of phylogenetic relatedness in shaping plant functional traits and the distribution of exotic species in their new ranges.
Specificity determinants of pathogens in forest
Authors: Cheng Keke , Yu Shixiao 
Published: October 2024

Abstract

Host‐specific pathogens have long been suggested to act as a major driver of species diversity in tropical forests. However, determining the degree of host specificity of potential pathogens coupled to key cellular characteristics of infection is difficult and time‐consuming. These challenges have delayed progress in relating the functional specificity of pathogenic fungi to ecological consequences.

We tested the pathogenicity of 27 (of 215) fungi that were isolated from surface sterilized roots of seedlings from four common tree species in a diverse subtropical forest. Inoculation experiments showed that six fungi exhibited strong pathogenicity on the host seedlings. Five of these only infected their specific hosts (i.e. host‐specific pathogen species).

Green fluorescent protein labelling revealed that in three host‐specific pathogens fungal hyphae were able to grow into the vascular tissues only in their specific host plant, in contrast to other fungal‐host combinations that exhibit non‐pathogenic interactions. This fluorescent labelling technique allows direct tracking of the progress of fungal infection in different host tissues.

Synthesis. By coupling the green fluorescent protein technique with standard host inoculation experiments, we determined the developmental differences between infections by pathogenic and non‐pathogenic fungi in a relatively simple and straightforward way. Our work provides a useful tool for rapidly screening and categorizing host–fungal interactions, reflecting the functional basis of host specificity of pathogenic fungi. More broadly, this technique can contribute to understanding the roles of pathogens in species coexistence and biodiversity maintenance in forest communities.
Can Trade Policy Uncertainty Drive Green Innovation? Empirical Evidence From the US–China Trade War
Authors: Cao Tingting , Hu Yifan 
Published: October 2024

ABSTRACTChina's rapid economic growth in recent years has coincided with heightened environmental regulations and an upsurge in greenhouse gas emissions, necessitating a greater emphasis on green innovation to mitigate environmental risks. Concurrently, the US–China trade war has elevated trade policy uncertainty (TPU). This study uses the TPU surge from the trade war as a quasi‐natural experiment, employing text analysis of annual reports to assess firms' TPU perceptions. Using a difference‐in‐differences method, we find that increased TPU significantly hinders green innovation. Firms' responses vary with environmental advantages, regulation levels, and government subsidies. Mechanisms include reduced environmental investment, decreased executive attention to environmental issues, and corporate social responsibility. These findings underscore the importance of a stable trading environment for promoting green innovation.
Foraging by predatory ants: A review
Authors: Dejean Alain , Orivel Jérôme , Cerdá Xim , Azémar Frédéric , Corbara Bruno , Touchard Axel 
Published: October 2024

AbstractIn this review, we show that predatory ants have a wide range of foraging behavior, something expected given their phylogenetic distance and the great variation in their colony size, life histories, and nesting habitats as well as prey diversity. Most ants are central‐place foragers that detect prey using vision and olfaction. Ground‐dwelling species can forage solitarily, the ancestral form, but generally recruit nestmates to retrieve large prey or a group of prey. Typically, ants are omnivorous, but some species are strict predators preying on detritivorous invertebrates or arthropod eggs, while those specialized on termites or other ants often have scouts that localize their target and then trigger a raid. They can use compounds that ease this task, including chemical insignificance, mimicry, and venoms triggering submissive behavior. Army ants include 8 Dorylinae and some species from other subfamilies, all having wingless queens and forming raids. Dorylinae from the Old World migrate irregularly to new nesting sites. The foraging of most New World species that prey on the brood of other ants is regulated by their biological cycle that alternates between a “nomadic phase” when the colony relocates between different places and a “stationary phase” when the colony stays in a bivouac constituting a central place. Among arboreal ants, dominant species forage in groups, detecting prey visually, but can use vibrations, particularly when associated with myrmecophytes. Some species of the genera Allomerus and Azteca use fungi to build a gallery‐shaped trap with small holes under which they hide to ambush prey.
Suppressing DUSP16 overexpression induced by ELK1 promotes neural progenitor cell differentiation in mouse models of Alzheimer's disease
Authors: Zhao Huimin , Mu Yao , Liang Anqi , Wei Jie , Lai Sixian , Li Xin , Chen Peipei , Li Hao , He Hua , Liu Xiaoquan , Liu Haochen 
Published: October 2024

AbstractEmerged evidence indicated that stimulating hippocampal neurogenesis is a potential strategy for restoring cognition in AD. Mitogen‐activated protein kinases (MAPKs) play an essential role in neurogenesis. Meanwhile, the enzymatic power of the phosphatases is much greater than that of kinases. Dual‐specificity phosphatase 16 (DUSP16), known to as a phosphatase negatively regulate MAPKs, may be implicated in neural differentiation. Nevertheless, the effect of DUSP16 on cognitive disorders by stimulating neural progenitor cell (NPC) differentiation in AD mice remains unclear. Our study demonstrates an association between DUSP16 SNPs and clinical progression in individuals with mild cognitive impairment (MCI). Besides, increased DUSP16 expression was detected in both 3xTg and SAMP8 mouse models of AD, accompanied by NPC neural differentiation impairments. By silencing DUSP16, the induction of neural differentiation, synaptic transmission, and cognitive benefits were observed in both AD mice. Furthermore, DUSP16 was involved in the process of NPC differentiation through regulating c‐Jun N‐terminal kinase (JNK) phosphorylation and SOX2 expression. Moreover, ETS transcription factor (ELK1) was involved in the DUSP16 transcription, which resulted in the upregulation of DUSP16 at the state of AD. Our data uncovers a potential regulatory role for DUSP16 in adult hippocampal neurogenesis (AHN) and provides a possibility to find a novel strategy for AD intervention.
Engaging under‐represented oldest old in research: An approach for inclusive recruitment
Authors: Paine Naomi , Lowe Melanie , Young Charlotte , Turrell Gavin 
Published: October 2024

AbstractIntroductionThose aged 80 years and over are the fastest‐growing sector of the Australian population but are often excluded from research. Oldest old people living alone, in disadvantaged neighbourhoods, and with ill health or dementia, face additional barriers that may hinder their participation in research.MethodsThis paper contributes timely critical commentary on methodological and ethical approaches to engaging under‐represented people in research. We draw on our experiences and reflections from a study of social exclusion of people aged 80 years and older living alone in government housing in Melbourne, Australia.Results and DiscussionWe suggest key factors to facilitate representation of this population group in future research. These factors include using doorknocking to gain access, cultivating trust with participants and gatekeepers, and conducting face‐to‐face home interviews. We also interrogate ethical and safety issues for researchers and oldest old participants including the potential for informed consent protocols to exclude this population group.ConclusionTo avoid unintentionally excluding the oldest old, researchers need to consider older persons' self‐determination and advocate for methods that ensure oldest old perspectives inform future healthy ageing planning and reduce possible health and well‐being inequities.
Generating and translating evidence for safe and effective medication management in aged care homes
Authors: Ea Annie M. L. , Cross Amanda J. , Martini Angelita , Wesson Jacqueline , Bell J. Simon 
Published: October 2024

Generating and translating high‐quality evidence is integral to providing safe and effective medication management for residents of aged care homes. Residents are often under‐represented in trials of medication effectiveness and safety. This paper reviews opportunities and challenges for generating and translating evidence for safe and effective medication management in aged care homes. There are an increasing number of randomized controlled trials (RCTs) being conducted in aged care homes. Observational studies can also help address the evidence‐practice gap arising from underrepresentation of residents in RCTs. Stepped‐wedge and helix counterbalanced designs may help overcome limitations of traditional RCTs for evaluating medication management interventions in the aged care setting. Strategies for generating evidence include building effective partnerships with aged care homes and organizations, using novel trial designs, leveraging existing data and knowledge sharing through international platforms. Strategies for translating evidence include using quality indicators for audit and feedback, provision of education and training, engaging internal and external stakeholders, and development of local action plans and guideline implementation tools. There is an emerging interest in the role of knowledge brokers to facilitate knowledge translation. Future directions for generating and translating evidence include strengthening international research collaboration, industry partnerships, standardizing aged care home data to support national and international comparisons, and optimizing the use of technology. Initiatives may include improving access to routinely collected administrative health and medication data for conducting high‐quality observational studies. Future studies should assess outcomes prioritized by residents to ensure that medication management strategies are tailored to their needs.
Dual Social Responsibility: The Pathway Effects and Mechanisms of Benevolent and Malevolent Actions on Firm Performance
Authors: Zhang Hong , Zhang Lei 
Published: October 2024

ABSTRACTWhile doing good things, enterprises may also be subject to subjective or unintentional behaviors of doing bad things, and corporate performance is comprehensively affected by its dual social responsibility. Using data from A‐share listed companies from 2010 to 2020, this paper, grounded in signaling theory, legitimacy theory, and stakeholder theory, analyzes the dual‐path effects, comprehensive effects, and boundary effects of corporate social responsibility (CSR) and corporate social irresponsibility (CSIR) on corporate performance. It innovatively introduces innovation efficiency as a mediating variable to examine its transmission mechanism and pathways in the influence of dual social responsibility on corporate performance. The study finds that CSR and CSIR have independent and heterogeneous effects on corporate performance, with the former exhibiting an inverted U‐shaped relationship with corporate performance and the latter consistently exerting a negative impact. The coexistence and interaction of CSR and CSIR have a comprehensive effect on corporate performance, where CSR performance can mitigate the negative impact of CSIR, and there exists a threshold effect. CSR has a nonlinear impact on innovation efficiency, and innovation efficiency plays a significant mediating role in the process of CSR and CSIR affecting corporate performance. The industrial environment competition plays a moderating role in the relationship between a company's dual social behavior and its performance. The higher the industrial environment competition, the more it will accelerate and intensify the negative impact of CSIR on corporate performance. Additionally, it will steepen the inverted U‐shaped curve of CSR influencing corporate performance and shift the inflection point to the left. This study not only extends the boundaries of research on the impact of CSIR on corporate performance but also provides insights for corporate social responsibility governance and ethical decision‐making in business.
Influence of Material, Sterilization, and Disinfection on the Accuracy of Three‐Dimensional Printed Surgical Templates: An In Vitro Study
Authors: Lan Dongping , Zhou Zheqing , Yang Yang , Xu Zhaoyu , Man Yi 
Published: October 2024

ABSTRACTObjectivesTo evaluate the influence of the three‐dimensional (3D) printing technology, material, sterilization, and disinfection on the accuracy of guided surgical templates.Material and MethodsFifty printed resin surgical templates were designed and fabricated using a digital light processing 3D printer with a photopolymerizing resin, and 50 printed metal surgical templates were designed and fabricated using a selective laser melting 3D printer with a titanium alloy. Templates from both groups were randomly divided into five subgroups involving different sterilization and disinfection procedures. The group without any sterilization or disinfection procedure served as the control group, whereas the other groups were used as the study groups (hydrogen peroxide gas plasma sterilization, 5% povidone‐iodine disinfection, 75% ethyl alcohol disinfection, and steam autoclave sterilization). Implant simulations were performed on the 3D‐printed resin models, and postoperative impressions were acquired with scan bodies attached to the implants. All surgical templates were digitally scanned. The root mean square was used to determine and quantify fabrication accuracy and reproducibility, and the definitive and planned implant positions were compared.ResultsThe printed resin templates exhibited lower fabrication accuracy and reproducibility, as well as higher 3D deviations, after steam autoclave sterilization (p < 0.001); however, the printed metal templates were not affected by the different sterilization or disinfection procedures (p > 0.05).ConclusionsPrinted metal surgical templates are viable alternatives for guided implant surgery. Preoperative steam or gas plasma sterilization is recommended, especially for metal templates, as resin templates show deformation and decreased accuracy after steam sterilization.Trial Registrationchictr.org.cn number: ChiCTR2400081334
Superior Prophylactic Effectiveness of a Recombinant FVIIIFc Over Standard Half‐Life FVIII in Hemophilia A: A‐SURE Study
Authors: Oldenburg Johannes , Hay Charles , Peyvandi Flora , Tagliaferri Annarita , Holme Pål Andrè , Álvarez‐Román María Teresa , Biron‐Andréani Christine , Malmström Håkan , Bystrická Linda , Lethagen Stefan ,   the A‐SURE Study Group
Published: October 2024

ABSTRACTObjectivesThe 24‐month, prospective, non‐interventional, European multicenter A‐SURE study evaluated the real‐world effectiveness of prophylaxis using an extended half‐life recombinant factor VIII (FVIII) Fc fusion protein, efmoroctocog alfa (hereinafter rFVIIIFc), compared with prophylaxis using standard half‐life (SHL) FVIII products in patients with hemophilia A.MethodsPrimary endpoints were annualized bleeding rate (ABR), annualized injection frequency, and annualized factor consumption. A comparative study design unique for an observational hemophilia study was implemented to reduce potential confounding in effectiveness estimates, wherein each patient prescribed rFVIIIFc was matched with one receiving SHL FVIII. Propensity scores were used for adjustment in statistical analyses.ResultsOutcomes for all primary endpoints were significantly better in the rFVIIIFc group (n = 184) compared with the SHL FVIII group (n = 170): mean ABR 1.5 versus 2.3 (difference of −0.8; p = 0.0147); mean annualized injection frequency 114.4 versus 169.2 (difference of −54.8; p < 0.0001); and mean annualized factor consumption 243 024.2 versus 288 718.6 International Units (difference of 45 694.5; p = 0.0003). rFVIIIFc was well tolerated, with no inhibitor development.ConclusionsrFVIIIFc has superior prophylactic effectiveness versus SHL FVIII, providing higher bleed protection with fewer injections and lower factor consumption.