bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxidation of C18 Hydroxy‐Polyunsaturated Fatty Acids to Epoxide or Ketone by Catalase‐Related Hemoproteins Activated with Iodosylbenzene
Authors: Teder Tarvi , Boeglin William E. , Brash Alan R. 
Published: June 2017

AbstractSmall catalase‐related hemoproteins with a facility to react with fatty acid hydroperoxides were examined for their potential mono‐oxygenase activity when activated using iodosylbenzene. The proteins tested were a Fusarium graminearum 41 kD catalase hemoprotein (Fg‐cat, gene FGSG_02217), a Pseudomonas fluorescens Pfl01 catalase (37.5 kD, accession number WP_011333788.1), and a Mycobacterium avium ssp. paratuberculosis 33 kD catalase (gene MAP‐2744c). 13‐Hydroxy‐octadecenoic acids (which are normally unreactive) were selected as substrates because these enzymes react specifically with the corresponding 13S‐hydroperoxides (Pakhomova et al. 18:2559–2568, 5; Teder et al. 1862:706–715, 14). In the presence of iodosylbenzene Fg‐cat converted 13S‐hydroxy‐fatty acids to two products: the 15,16‐double bond of 13S‐hydroxy α‐linolenic acid was oxidized stereospecifically to the 15S,16R‐cis‐epoxide or the 13‐hydroxyl was oxidized to the 13‐ketone. Products were identified by UV, HPLC, LC–MS, NMR and by comparison with authentic standards prepared for this study. The Pfl01‐cat displayed similar activity. MAP‐2744c oxidized 13S‐hydroxy‐linoleic acid to the 13‐ketone, and epoxidized the double bonds to form the 9,10‐epoxy‐13‐hydroxy, 11,12‐epoxy‐13‐hydroxy, and 9,10‐epoxy‐13‐keto derivatives; equivalent transformations occurred with 9S‐hydroxy‐linoleic acid as substrate. In parallel incubations in the presence of iodosylbenzene, human catalase displayed no activity towards 13S‐hydroxy‐linoleic acid, as expected from the highly restricted access to its active site. The results indicated that with suitable transformation to Compound I, monooxygenase activity can be demonstrated by these catalase‐related hemoproteins with tyrosine as the proximal heme ligand.
Preclinical Biokinetic Modelling of Tc-99m Radiophamaceuticals Obtained from Semi-Automatic Image Processing
Authors: Cornejo-Aragón Luz G. , Santos-Cuevas Clara L. , Ocampo-García Blanca E. , Chairez-Oria Isaac , Diaz-Nieto Lorenza , García-Quiroz Janice 
Published: June 2017

Abstract
The aim of this study was to develop a semi automatic image processing algorithm (AIPA) based on the simultaneous information provided by X-ray and radioisotopic images to determine the biokinetic models of Tc-99m radiopharmaceuticals from quantification of image radiation activity in murine models. These radioisotopic images were obtained by a CCD (charge couple device) camera coupled to an ultrathin phosphorous screen in a preclinical multimodal imaging system (Xtreme, Bruker). The AIPA consisted of different image processing methods for background, scattering and attenuation correction on the activity quantification. A set of parametric identification algorithms was used to obtain the biokinetic models that characterize the interaction between different tissues and the radiopharmaceuticals considered in the study. The set of biokinetic models corresponded to the Tc-99m biodistribution observed in different ex vivo studies. This fact confirmed the contribution of the semi-automatic image processing technique developed in this study.
Vectorial backstepping method–based trajectory tracking control for an under-actuated stratospheric airship
Authors: Liu S. Q. , Gong S. J. , Li Y. X. , Lu Z. R. 
Published: June 2017

ABSTRACTA new trajectory tracking control approach for an under-actuated stratospheric airship is proposed. There is a two-level structure of the proposed controller. A low-level controller based on non-linear vectorial backstepping method, with the rigid-body dynamics expressed on vector form, stabilises the attitude and velocity of the airship, while a high-level controller performs guidance and trajectory tracking task in the three-dimensional (3D) space. Furthermore, a control allocation module based on the active set algorithm is incorporated into the low-level controller to optimise the practical control inputs under constraints of actuator saturation. The closed-loop trajectory tracking control plant is proved to be globally exponentially stable through the Lyapunov theory. Finally, simulations show that the vectorial backstepping trajectory tracking controller can achieve desired tracking performances even if the airship is affected by parametric uncertainties and exogenous disturbances.
THE FULL TAILS GAMMA DISTRIBUTION APPLIED TO MODEL EXTREME VALUES
Authors: del Castillo Joan , Daoudi Jalila , Serra Isabel 
Published: June 2017

AbstractIn this paper, we introduce the simplest exponential dispersion model containing the Pareto and exponential distributions. In this way, we obtain distributions with support (0, ∞) that in a long interval are equivalent to the Pareto distribution; however, for very high values, decrease like the exponential. This model is useful for solving relevant problems that arise in the practical use of extreme value theory. The results are applied to two real examples, the first of these on the analysis of aggregate loss distributions associated to the quantitative modelling of operational risk. The second example shows that the new model improves adjustments to the destructive power of hurricanes, which are among the major causes of insurance losses worldwide.
The Nature of the Relationship Between Corporate Identity and Corporate Sustainability: Evidence from The Retail Industry
Authors: Simões Cláudia , Sebastiani Roberta 
Published: June 2017

ABSTRACT:This article addresses the nature of the interface between corporate sustainability and corporate identity at both the strategic and instrumental levels. We developed an empirical qualitative study in two countries in Southern Europe addressing retailers who are actively engaged in pursuing corporate-sustainability strategies. Data sources include in-depth interviews, observations, and physical artifacts of identity (digital and printed documents). Findings reveal that, at a strategic level, corporate sustainability is embedded in corporate identity reflecting the company’s strategy. Companies also instrumentally use corporate identity to operationalize corporate sustainability strategies. Organizations show different patterns in the way they bridge corporate sustainability and identity. The contributions of this article are threefold: it reports the symbiotic relationship between corporate sustainability and corporate identity; it scrutinizes how corporate sustainability and corporate identity are integrated at the strategic and operational levels; and it establishes distinct patterns at the interface of corporate sustainability and corporate identity.
ω-STABILITY AND MORLEY RANK OF BILINEAR MAPS, RINGS AND NILPOTENT GROUPS
Authors: MYASNIKOV ALEXEI G. , SOHRABI MAHMOOD 
Published: June 2017

AbstractIn this paper we study the algebraic structure ofω-stable bilinear maps, arbitrary rings, and nilpotent groups. We will also provide rather complete structure theorems for the above structures in the finite Morley rank case.
A CO-ANALYTIC COHEN-INDESTRUCTIBLE MAXIMAL COFINITARY GROUP
Authors: FISCHER VERA , SCHRITTESSER DAVID , TÖRNQUIST ASGER 
Published: June 2017

AbstractAssuming that every set is constructible, we find a${\text{\Pi }}_1^1 $maximal cofinitary group of permutations of$\mathbb{N}$which is indestructible by Cohen forcing. Thus we show that the existence of such groups is consistent with arbitrarily large continuum. Our method also gives a new proof, inspired by the forcing method, of Kastermans’ result that there exists a${\text{\Pi }}_1^1 $maximal cofinitary group inL.
Dietaryl-tryptophan leaves a lasting impression on the brain and the stress response
Authors: Höglund Erik , Øverli Øyvind , Andersson Madelene Å. , Silva Patricia , Laursen Danielle Caroline , Moltesen Maria M. , Krogdahl Åshild , Schjolden Joachim , Winberg Svante , Vindas Marco A. , Mayer Ian , Hillestad Marie 
Published: June 2017

AbstractComparative models suggest that effects of dietary tryptophan (Trp) on brain serotonin (5-hydroxytryptamine; 5-HT) neurochemistry and stress responsiveness are present throughout the vertebrate lineage. Moreover, hypothalamic 5-HT seems to play a central role in control of the neuroendocrine stress axis in all vertebrates. Still, recent fish studies suggest long-term effects of dietary Trp on stress responsiveness, which are independent of hypothalamic 5-HT. Here, we investigated if dietary Trp treatment may result in long-lasting effects on stress responsiveness, including changes in plasma cortisol levels and 5-HT neurochemistry in the telencephalon and hypothalamus of Atlantic salmon. Fish were fed diets containing one, two or three times the Trp content in normal feed for 1 week. Subsequently, fish were reintroduced to control feed and were exposed to acute crowding stress for 1 h, 8 and 21 d post Trp treatment. Generally, acute crowding resulted in lower plasma cortisol levels in fish treated with 3×Trp compared with 1×Trp- and 2×Trp-treated fish. The same general pattern was reflected in telencephalic 5-HTergic turnover, for which 3×Trp-treated fish showed decreased values compared with 2×Trp-treated fish. These long-term effects on post-stress plasma cortisol levels and concomitant 5-HT turnover in the telencephalon lends further support to the fact that the extrahypothalamic control of the neuroendocrine stress response is conserved within the vertebrate lineage. Moreover, they indicate that trophic/structural effects in the brain underlie the effects of dietary Trp treatment on stress reactivity.
ASSESSING NITROGEN NUTRITIONAL STATUS, BIOMASS AND YIELD OF COTTON WITH NDVI, SPAD AND PETIOLE SAP NITRATE CONCENTRATION
Authors: ZHOU GUISU , YIN XINHUA 
Published: June 2017

SUMMARYCanopy normalized difference vegetation index (NDVI), soil plant analysis development (SPAD) reading and petiole sap NO3−‒N concentration are increasingly used as quick and non-destructive methods to monitor plant N nutrition and growth status and predict yield of crops. However, little information is available on the comparisons of these three methods in assessing N nutrition, growth and yield for cotton (Gossypium hirsutum L.). Four N rates (0, 34, 67 and 101 kg N ha−1) under two cover conditions [no cover crop and hairy vetch (Vicia villosa) crop] in a 33-year long-term field trial were used to evaluate how canopy NDVI, SPAD reading (related to chlorophyll content) and petiole sap NO3−‒N concentration (conventional method) are able to assess N nutrition and plant biomass and predict yield for cotton. Canopy NDVI and SPAD readings responded less sensitively to N rates than petiole sap NO3−‒N. The responses of NDVI and SPAD reading to N rates were generally reduced due to the winter cover crop with hairy vetch. Significant and positive correlations existed mostly among NDVI, SPAD reading, and petiole sap NO3−‒N concentration. Canopy NDVI during mid-bloom to late bloom and SPAD reading during early bloom to late bloom were effective alternative methods for assessing cotton N nutrition status. The SPAD reading at late bloom was an effective parameter to estimate cotton biomass. The NDVI at early square and SPAD reading during early square to mid-bloom were effective for cotton yield prediction.
Symptoms of depression in a large healthy population cohort are related to subjective memory complaints and memory performance in negative contexts
Authors: Schweizer S. , Kievit R. A. , Emery T. ,   Cam-CAN, Henson R. N. 
Published: June 2017

BackgroundDecades of research have investigated the impact of clinical depression on memory, which has revealed biases and in some cases impairments. However, little is understood about the effects of subclinical symptoms of depression on memory performance in the general population.MethodsHere we report the effects of symptoms of depression on memory problems in a large population-derived cohort (N= 2544), 87% of whom reported at least one symptom of depression. Specifically, we investigate the impact of depressive symptoms on subjective memory complaints, objective memory performance on a standard neuropsychological task and, in a subsample (n= 288), objective memory in affective contexts.ResultsThere was a dissociation between subjective and objective memory performance, with depressive symptoms showing a robust relationship with self-reports of memory complaints, even after adjusting for age, sex, general cognitive ability and symptoms of anxiety, but not with performance on the standardised measure of verbal memory. Contrary to our expectations, hippocampal volume (assessed in a subsample,n= 592) did not account for significant variance in subjective memory, objective memory or depressive symptoms. Nonetheless, depressive symptoms were related to poorer memory for pictures presented in negative contexts, even after adjusting for memory for pictures in neutral contexts.ConclusionsThus the symptoms of depression, associated with subjective memory complaints, appear better assessed by memory performance in affective contexts, rather than standardised memory measures. We discuss the implications of these findings for understanding the impact of depressive symptoms on memory functioning in the general population.
Post-traumatic stress disorder associated with sexual assault among women in the WHO World Mental Health Surveys
Authors: Scott K. M. , Koenen K. C. , King A. , Petukhova M. V. , Alonso J. , Bromet E. J. , Bruffaerts R. , Bunting B. , de Jonge P. , Haro J. M. , Karam E. G. , Lee S. , Medina-Mora M. E. , Navarro-Mateu F. , Sampson N. A. , Shahly V. , Stein D. J. , Torres Y. , Zaslavsky A. M. , Kessler R. C. 
Published: June 2017

BackgroundSexual assault is a global concern with post-traumatic stress disorder (PTSD), one of the common sequelae. Early intervention can help prevent PTSD, making identification of those at high risk for the disorder a priority. Lack of representative sampling of both sexual assault survivors and sexual assaults in prior studies might have reduced the ability to develop accurate prediction models for early identification of high-risk sexual assault survivors.MethodsData come from 12 face-to-face, cross-sectional surveys of community-dwelling adults conducted in 11 countries. Analysis was based on the data from the 411 women from these surveys for whom sexual assault was the randomly selected lifetime traumatic event (TE). Seven classes of predictors were assessed: socio-demographics, characteristics of the assault, the respondent's retrospective perception that she could have prevented the assault, other prior lifetime TEs, exposure to childhood family adversities and prior mental disorders.ResultsPrevalence of Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) PTSD associated with randomly selected sexual assaults was 20.2%. PTSD was more common for repeated than single-occurrence victimization and positively associated with prior TEs and childhood adversities. Respondent's perception that she could have prevented the assault interacted with history of mental disorder such that it reduced odds of PTSD, but only among women without prior disorders (odds ratio 0.2, 95% confidence interval 0.1–0.9). The final model estimated that 40.3% of women with PTSD would be found among the 10% with the highest predicted risk.ConclusionsWhether counterfactual preventability cognitions are adaptive may depend on mental health history. Predictive modelling may be useful in targeting high-risk women for preventive interventions.
The politics of Flamenco: La leyenda del tiempo and ideology
Authors: Casellas Jesús López-Peláez 
Published: June 2017

AbstractFlamenco music has consistently been misrepresented as an exclusively aesthetic construct only concerned with the transmission of essential and timeless values and with the production of beauty. This insidious mystification is a consequence of the influence that several decades of nacionalcatolicismo (the ideological construction of Franco's Spain) has had over flamenco, together with its obscure and unclear origins, about three centuries ago. This paper will suggest that, against this commonly held belief, flamenco music frequently has a political agenda, which may be explicitly expressed in the lyrics of the cantes, or implicitly apparent in the formal and ideological structure of flamenco itself and its recordings. Camarón and Pachón's seminal La leyenda del tiempo (Polygram, 1979) will be explored both in its own right as one of the peaks of contemporary (new) flamenco and also as a clear showcase of how flamenco may be politicized in various ways and serve a clearly ideological purpose without neglecting its musical and aesthetic role.
Beyond the playlist: commercial radio as music culture
Authors: Uimonen Heikki 
Published: June 2017

AbstractThis article presents the historical transformation of Finnish commercial radio popular music policies from 1985 to 2005 and contemplates the role of terrestrial radio in contemporary digital age. It argues that a sender-centred paradigm of early commercial radio was replaced swiftly by receiver-centred paradigm, which has been applied since the early 1990s. The change of radio music cultures is described in detail by dividing it into three different eras:Block Radio, Format RadioandMedia Convergence. The study draws on the research project consisting of case studies analysing the music content of various radio stations. The primary empirical data is composed of 32 interviews of radio personnel and the analysis of 4,500 individual songs broadcast by popular music radio stations with newspaper and journal articles supporting the primary data. Radio music culture is approached theoretically from the ethnomusicological perspective and thus defined as all practices that have an effect on broadcast music, including the processes of acquiring, selecting and governing music. The empirical results of the study show that the transformation of radio music cultures is affected by economic, technological, legal, organisational and cultural factors.
ONLINE AND OFFLINE EFFECTS OF L1 PRACTICE IN L2 GRAMMAR LEARNING
Authors: McManus Kevin , Marsden Emma 
Published: June 2017

AbstractThis study partially replicates McManus and Marsden (2017), who found that providing L1 explicit information (EI) plus task-essential practice led L2 learners to make more accurate and faster interpretations of French morphosyntax. The current study removed the original study’s L1 EI component to examine the role of the L1 practice. This design tested whether providing L1 task-essential practice only (alongside a core treatment of L2 EI plus L2 practice) resulted in similar online and offline learning gains compared to the original study’s L1 EI plus L1 practice. We used the same online and offline tests, with a similar population of English-speaking learners of L2 French (n = 19). For accuracy and speed of online and offline L2 processing, the findings suggest that additional L1 practice without L1 EI was no more beneficial than L2 EI plus L2 practice alone, indicating that the original study’s combination of additional L1 EI with L1 practice appeared to contribute to previously observed learning benefits.
Preoperative malnutrition is associated with increased mortality and adverse outcomes after paediatric cardiac surgery
Authors: Ross Faith , Latham Gregory , Joffe Denise , Richards Michael , Geiduschek Jeremy , Eisses Michael , Thompson Douglas , Radman Monique 
Published: June 2017

AbstractBackgroundMalnutrition is common in children with CHD and is likely to place them at an increased risk for adverse surgical outcomes. We sought to evaluate the impact of preoperative malnutrition on outcomes after paediatric cardiac surgery.MethodsWe conducted a retrospective analysis of patients from age 0 to 5 years undergoing cardiac surgery at Seattle Children’s Hospital from 2006 to 2015. We used regression modelling to examine the impact of malnutrition on surgical outcomes.ResultsWe found a non-linear relationship between low height-for-age and weight-for-age z-scores and mortality after surgery. In the range of z-score ⩽−2, each additional unit decrease in height-for-age or weight-for-age z-score was associated with a 2.9 or 2.1% increased risk for mortality, respectively. Each unit decrease in height-for-age z-score was associated with a 1.2% increased risk for cardiac arrest, 1.1% increased risk for infection, and an average of 1.7 additional hours of mechanical ventilation, 6 hours longer ICU stay, and 13 hours longer hospital stay. Each unit decrease in weight-for-age z-score was associated with a 0.7% increased risk for cardiac arrest, 0.8% increased risk for infection, and an average of 1.9 additional hours of mechanical ventilation and 5.3 additional hours of ICU stay.ConclusionsThis study is unique in demonstrating a significant association between malnutrition and 30-day mortality and other adverse outcomes after paediatric cardiac surgery in a mixed population of CHD patients. By evaluating nutritional status as a continuous variable, we were able to clearly distinguish the point at which malnutrition begins to affect mortality.
Involvement of the Left Supramarginal Gyrus in Manipulation Judgment Tasks: Contributions to Theories of Tool Use
Authors: Lesourd Mathieu , Osiurak François , Navarro Jordan , Reynaud Emanuelle 
Published: June 2017

AbstractObjectives: Two theories of tool use, namely the gesture engram and the technical reasoning theories, make distinct predictions about the involvement of the left inferior parietal lobe (IPL) in manipulation judgement tasks. The objective here is to test these alternative predictions based on previous studies on manipulation judgment tasks using transcranial magnetic stimulations (TMS) targeting the left supramarginal gyrus (SMG). Methods: We review recent TMS studies on manipulation judgement tasks and confront these data with predictions made by both tool use theories. Results: The left SMG is a highly intertwined region, organized following several functionally distinct areas and TMS may have disrupted a cortical network involved in the ability to use tools rather than only one functional area supporting manipulation knowledge. Moreover, manipulation judgement tasks may be impaired following virtual lesions outside the IPL. Conclusions: These data are more in line with the technical reasoning hypothesis, which assumes that the left IPL does not store manipulation knowledge per se. (JINS, 2017, 23, 685–691)
Interleukin 33 exacerbates antigen driven airway hyperresponsiveness, inflammation and remodeling in a mouse model of asthma
Authors: Sjöberg L. C. , Nilsson A. Zoltowska , Lei Y. , Gregory J. A. , Adner M. , Nilsson G. P. 
Published: June 2017

AbstractInterleukin 33 (IL-33) represents a potential link between the airway epithelium and induction of Th2-type inflammatory responses associated with the development of asthma. This study investigated the potential of IL-33 to exacerbate antigen driven asthma responses. An ovalbumin (OVA) asthma model was used in which sensitized C57BL/6 mice were exposed to IL-33 before each OVA challenge. IL-33 given to sensitized mice acted synergistically with antigen and aggravated airway inflammation, hyperresponsiveness and remodeling compared with mice that were only OVA sensitized and challenged and mice that were only exposed to IL-33. Elevated levels of local and systemic mast cell protease mMCP-1, as well as antigen-specific IgE production, were observed following IL-33 administration to sensitized mice. Similarly, exposing OVA-sensitized mice to IL-33 increased the Th2 cytokine levels, including IL-4, IL-5 and IL-13. Furthermore, IL-33 and OVA administration to OVA-sensitized mice increased ILC2s in the lung, suggesting a role for ILC2s in IL-33-mediated exacerbation of OVA-induced airway responses. Collectively, these findings show that IL-33 aggravates important features of antigen-driven asthma, which may have implications for asthma exacerbations.