bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bond Strength of a Novel One Bottle Multi-mode Adhesive to Human Dentin After
Six Months of Storage
Authors: Manfroi Fernanda Borguetti , Marcondes Maurem Leitão , Somacal Deise Caren , Borges Gilberto Antonio , Júnior Luiz Henrique Burnett , Spohr Ana Maria 
Published: June 2016

Objective:
The aim of the study was to evaluate the microtensile bond strength (µTBS) of Scotchbond Universal to dentin using the etch-and-rinse or the self-etch technique after 24 h and 6 months of storage.

Materials and Methods:
Flat dentin surfaces were obtained in 24 third molars. The teeth were divided into four groups: G1 – Scotchbond Universal applied in the etch-and-rinse mode; G2 – Scotchbond Universal applied in the self-etch mode; G3 – Scotchbond Multi-Purpose; G4 – Clearfil SE Bond. A block of composite was built on the adhesive area. The tooth/resin sets were cut parallel to the long axis to obtain 40 beams (~0.8 mm2) for each group. Twenty specimens were immediately submitted to the µTBS test, and the remaining 20 were stored in water for 6 months. Failures and the adhesive interface were analyzed by SEM.

Results:
According to two-way ANOVA, the interaction between adhesive and storage time was significant (p=0.015).The µTBS (MPa) means were the following: 24 h – G1 (39.37±10.82), G2 (31.02±13.76), G3 (35.09±14.03) and G4 (35.84±11.06); 6 months – G1 (36.99±8.78), G2 (40.58±8.07), G3 (32.44±6.07) and G4 (41.75±8.25). Most failures were mixed. Evidence of hybrid layer and numerous resin tags were noted for Scotchbond Universal applied with the etch-and-rinse mode and Scotchbond Multi-Purpose. A thinner hybrid layer and fewer resin tags were noted for Scotchbond Universal applied in the self-etch mode and Clearfil SE Bond.

Conclusion:
The results indicate that the µTBS for Scotchbond Universal is comparable to the gold-standard adhesives. Scotchbond Universal applied in the self-etch mode and Clearfil SE Bond revealed higher bond stability compared to the etch-and-rinse mode.
CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes
Authors: Dawed Adem Y. , Donnelly Louise , Tavendale Roger , Carr Fiona , Leese Graham , Palmer Colin N.A. , Pearson Ewan R. , Zhou Kaixin 
Published: June 2016

OBJECTIVE
Thiazolidinediones (TZDs) are putatively transported into the liver by OATP1B1 (encoded by SLCO1B1) and metabolized by CYP450 2C8 enzyme (encoded by CYP2C8). While CYP2C8*3 has been shown to alter TZD pharmacokinetics, it has not been shown to alter efficacy.

RESEARCH DESIGN AND METHODS
We genotyped 833 Scottish patients with type 2 diabetes treated with pioglitazone or rosiglitazone and jointly investigated association of variants in these two genes with therapeutic outcome.

RESULTS
The CYP2C8*3 variant was associated with reduced glycemic response to rosiglitazone (P = 0.01) and less weight gain (P = 0.02). The SLCO1B1 521T&gt;C variant was associated with enhanced glycemic response to rosiglitazone (P = 0.04). The super responders defined by combined genotypes at CYP2C8 and SLCO1B1 had a 0.39% (4 mmol/mol) greater HbA1c reduction (P = 0.006) than the poor responders. Neither of the variants had a significant impact on pioglitazone response.

CONCLUSIONS
These results show that variants in CYP2C8 and SLCO1B1 have a large clinical impact on the therapeutic response to rosiglitazone and highlight the importance of studying transporter and metabolizing genes together in pharmacogenetics.
Does β-Cell Autoimmunity Play a Role in Cystic Fibrosis–Related Diabetes? Analysis Based on the German/Austrian Diabetes Patienten Verlaufsdokumentation Registry
Authors: Konrad Katja , Kapellen Thomas , Lilienthal Eggert , Prinz Nicole , Bauer Maria , Thon Angelika , Rietschel Ernst , Wiemann Dagobert , Holl Reinhard W. 
Published: June 2016

OBJECTIVEResearch on β-cell autoimmunity in cystic fibrosis (CF)–related diabetes (CFRD) is still rare. We aimed to analyze the frequency of β-cell autoimmunity and the influence on age at diabetes onset, insulin requirement, type of insulin therapy, and hypoglycemic or ketoacidotic events in patients with CFRD compared with antibody-negative patients with CFRD in the Diabetes Patienten Verlaufsdokumentation (DPV) registry.RESEARCH DESIGN AND METHODSWe analyzed data of 837 patients with CFRD in the German/Austrian DPV database by multivariable mixed-regression modeling.RESULTSIn our cohort, 8.5% of patients with CFRD (n = 72) were found to be β-cell antibody positive. There was a female preponderance in this patient group: 65.3 vs. 57.6%. Diabetes onset (median [interquartile range]) was earlier (14.00 [10.15–15.90] vs. 16.10 [13.50–21.20] years; P &lt; 0.005), and insulin dose/kg body weight was higher (0.95 [0.61–1.15] vs. 0.67 [0.33–1.04] IU/kg; P &lt; 0.05). There were also differences in the type of insulin treatment. Insulin pump therapy was used significantly more often in patients with CFRD with β-cell autoimmunity (18.2 vs. 6.4%; P &lt; 0.05). The differences for multiple daily injections (ICT) and conventional therapy (CT) were not significant (ICT: 67.7 vs. 79.0%; CT: 15.2 vs. 14.6). Oral antidiabetic agents were rarely used in both groups. Rate of severe hypoglycemia with coma and rate of ketoacidosis were higher in antibody-positive patients (hypoglycemia with coma: 8.0 vs. 1.4, P &lt; 0.05; ketoacidosis: 9.3 vs. 0.9, P &lt; 0.05).CONCLUSIONSPresence of β-cell autoantibodies in our cohort of patients with CFRD (8.5%) appeared to be greater than in the general population and was associated with female sex, earlier onset of diabetes, and higher insulin requirement. Insulin pump therapy was used significantly more often in patients with β-cell antibodies. Severe hypoglycemia and ketoacidosis were significantly more frequent in CFRD with β-cell autoimmunity compared with β-cell antibody-negative patients with CFRD.
Naissance d'Electre
Authors: Moreau Alain 
Published: June 2016

The birth of Electra.
The origins of the myth of Electra are perhaps to be looked for in the Mesopo- tamian area. At any rate, there is no mention of that heroine in Homer. A mere name for a long time, she very progressively came in to existence in Hesoid, Xanthos, or on some vase paintings. Aischylos kept her in a passive role, as a character devoid of any heroism. On the contrary, Sophocles and Euripides brought the to its term, and with them Electra becomes a powerful and impressive, even bloodthirsty, character, worthy of her mother to whom she bears close resemblance : the heroine has achieved her full stature. Meanwhile, the gods have withdrawn into the blakground and Orestes has become a dimmer character.
Galba et Tarraco : à propos de Suétone, Galba, XII, 1
Authors: Le Roux Patrick 
Published: June 2016

Galba and Tarraco : on Suetonius' Galba XII, 1.
In his French translation of Suetonius' Galba, XII, 1, H. Ailloud did not pay enough attention to the technical character of the vocabulary used by the As a result, there are errors of interpretation and the historical importance of the text is distorted. In Suetonius' work, the psychological portraits of Roman do not correspond to abstract models ; they are expressive of actual between individuals and the reality of imperial politics. This paper aims to point out the need for fruitful collaboration between philologists and historians in their search for new approaches to Roman political history.
Les combats de coq furent-ils un sport ?
Authors: Dumont Jacques 
Published: June 2016

"Was cock-fighting a sport ?" .
In Greece the cock was a bird recently imported from India via Persia in the 6th century BC. Stripped of its exotic allurement and a good deal of its sacredness it was soon to be used as a lover's gift and a plaything. The Greeks insisted on reading into cockfighting a real agôn on the pattern of heroic contests, while it was only a ludus , a game determined by the bird's instincts and the very peculiar biological structure of its eye : double fovea. The game may have been a way to compensate for the loss of military power in Athens, but, despite Elian's anecdote, it never was a noble activity. In a like spirit, the Greeks long opposed any gladiatorial fight on their soil.
Teucros dans Hélène d'Euripide
Authors: Karsaï György 
Published: June 2016

Teucros arrive en Egypte avec un but précis dans la tragédie d'Euripide : il doit rencontrer Théonoé, la prophétesse pour mettre fin à ses souffrances en apprenant d'elle l'itinéraire qu'il devra suivre pour arriver à Chypre, où il trouvera une nouvelle patrie (vv. 140-150).
De l'autre côté nous avons une Hélène, fidèle épouse de Ménélas, qui vit en Egypte depuis le début de la guerre de Troie, grâce à a ruse d'Héra. Elle a un seul objectif dans sa vie : retourner à Sparte, c'est-à-dire retrouver son mari, sa famille, prouver son innocence et regagner sa place dans la société.
Hélène et Teucros sont les deux personnages de la pièce qui ont besoin d'informations pour réaliser leur plan. C'est une question de vie ou de mort d'obtenir les informations nécessaires : ni l'une ni l'autre ne pourra continuer son chemin qu'après avoir réussi dans Yagôn qui les oppose (vv. 68-163).
Hélène se trouve dans une situation sans espoir : les assauts amoureux du nouveau roi - le frère de Théonoé ! - rendent sa vie de plus en plus difficile et sa fidélité (pareille à celle d'une Pénélope) est en danger. Elle doit fuir ce mariage en vue, mais pour préparer son évasion, elle doit connaître l'histoire de la guerre de Troie, l'opinion des Grecs sur le « fantôme Hélène », le degré de haine de ses compatriotes contre elle.
La première scène de la pièce peut être interprétée dans plusieurs perspectives :
1) c'est une rencontre d'Hélène et du monde grec duquel elle avait été arrachée de force il y a très longtemps ;
2) les rencontres d'Hélène avec les hommes dans la pièce, l'examen en parallèle des scènes Hélène-Teucros et Hélène-Ménélas ;
3) les niveaux de connaissance du monde ;
4) les moyens utilisés par Hélène et par Teucros pour arriver à leurs fins ;
5) manipulation et caractère d'Hélène et de Teucros dans la tragédie d'Euripide.
Les fora tripartites de Gaule romaine : norme ou normalisation ?
Authors: Sablayrolles Robert 
Published: June 2016

Roman Gaul's tripartite fora : normative or normalized ?
It has been traditionally held since the studies by R. Goodchild, A. Grenier and J. B. Ward- Perkins till those by C. Goudineau or P. Gros, that the three-component y»ni in Roman Gaul are derived from a North Italian pattern, later developed and propagated from southern to Belgic Gaul. The results of recent excavations at St Bertrand de Comminges provide food for thought. The notion of norm is likely to need nuancing and be reserved more to the political, economic and social environment of the financing partners than to the actual execution of the building. As a matter of fact, the amount of local intervention in that field appears to be at least as important as that of the rules pertaining to urbanistic or architectural cartoons.
Du parchemin à l'édition critique
Authors: François Paul 
Published: June 2016

From parchment to critical edition.
Any research based on a literary document is expected to rely on a dependable text. Meant for a public only slightly informed of the conditions and procedure of a scientific edition this contribution deals with the supports, the material presentation and the reproduction of ancient texts. It then describes the accidents that may adulterate their transmission, the processes of recension and collation of the manuscripts, the principles at work in the emendation and establishment of the text down to the writing of the critical apparatus. Livy's book XXIX supplies instances and illustrations of those various stages.
À propos du réemploi d'éléments architectoniques lors de reconstructions antiques : quelques exemples à Belo
Authors: Fincker Myriam , Sillières Pierre 
Published: June 2016

About the reemployment of architectonic elements in ancient reconstructions : a few instances from Belo
Summary. The study of the chief buildings of Belo, a Roman town in Betica, chiefly that of its Capitolium, its temple of Isis and its rampart shows the importance for the city's history of two great phases of destruction, towards 50 and 250 A.D., presumably brought about by earthquakes. The observations carried out on those monuments induce one to think that the method of reconstruction consisted in the reemployment in the new fabric of a number of blocks from the previous wrecked buildings, carved blocks in particular. It is the reemployment of decorative architectural elements which explains the chronological gap of over half a century between the Augustan decor of monuments of the High Empire Belo and the edifices proper which the stratigraphie excavation unmistakably ascribes to the second half of the century.
DISCOVERY OF BROAD SOFT X-RAY ABSORPTION LINES FROM THE QUASAR WIND IN PDS 456
Authors: Reeves J. N. , Braito V. , Nardini E. , Behar E. , O’Brien P. T. , Tombesi F. , Turner T. J. , Costa M. T. 
Published: June 2016

ABSTRACT
High-resolution soft X-ray spectroscopy of the prototype accretion disk wind quasar, PDS 456, is presented. Here, the XMM-Newton reflection grating spectrometer spectra are analyzed from the large 2013–2014 XMM-Newton campaign, consisting of five observations of approximately 100 ks in length. During the last observation (OBS. E), the quasar is at a minimum flux level, and broad absorption line (BAL) profiles are revealed in the soft X-ray band, with typical velocity widths of

km s−1. During a period of higher flux in the third and fourth observations (OBS. C and D, respectively), a very broad absorption trough is also present above 1 keV. From fitting the absorption lines with models of photoionized absorption spectra, the inferred outflow velocities lie in the range

. The absorption lines likely originate from He and H-like neon and L-shell iron at these energies. A comparison with earlier archival data of PDS 456 also reveals a similar absorption structure near 1 keV in a 40 ks observation in 2001, and generally the absorption lines appear most apparent when the spectrum is more absorbed overall. The presence of the soft X-ray BALs is also independently confirmed by an analysis of the XMM-Newton EPIC spectra below 2 keV. We suggest that the soft X-ray absorption profiles could be associated with a lower ionization and possibly clumpy phase of the accretion disk wind, where the latter is known to be present in this quasar from its well-studied iron K absorption profile and where the wind velocity reaches a typical value of 0.3c.
THE ALFALFA Hα SURVEY. I. PROJECT DESCRIPTION AND THE LOCAL STAR FORMATION RATE DENSITY FROM THE FALL SAMPLE
Authors: Sistine Angela Van , Salzer John J. , Sugden Arthur , Giovanelli Riccardo , Haynes Martha P. , Janowiecki Steven , Jaskot Anne E. , Wilcots Eric M. 
Published: June 2016

ABSTRACT
The ALFALFA Hα survey utilizes a large sample of H i-selected galaxies from the ALFALFA survey to study star formation (SF) in the local universe. ALFALFA Hα contains 1555 galaxies with distances between ∼20 and ∼100 Mpc. We have obtained continuum-subtracted narrowband Hα images and broadband R images for each galaxy, creating one of the largest homogeneous sets of Hα images ever assembled. Our procedures were designed to minimize the uncertainties related to the calculation of the local SF rate density (SFRD). The galaxy sample we constructed is as close to volume-limited as possible, is a robust statistical sample, and spans a wide range of galaxy environments. In this paper, we discuss the properties of our Fall sample of 565 galaxies, our procedure for deriving individual galaxy SF rates, and our method for calculating the local SFRD. We present a preliminary value of log(SFRD[M
⊙ yr−1 Mpc−3]) = −1.747 ± 0.018 (random) ±0.05 (systematic) based on the 565 galaxies in our Fall sub-sample. Compared to the weighted average of SFRD values around z ≈ 2, our local value indicates a drop in the global SFRD of a factor of 10.2 over that lookback time.
SPITZER IRAC SPARSELY SAMPLED PHASE CURVE OF THE EXOPLANET WASP-14B
Authors: Krick J. E. , Ingalls J. , Carey S. , Braun K. von , Kane S. R. , Ciardi D. , Plavchan P. , Wong I. , Lowrance P. 
Published: June 2016

ABSTRACT
Motivated by a high Spitzer IRAC oversubscription rate, we present a new technique of randomly and sparsely sampling the phase curves of hot Jupiters. Snapshot phase curves are enabled by technical advances in precision pointing as well as careful characterization of a portion of the central pixel on the array. This method allows for observations which are a factor of approximately two more efficient than full phase curve observations, and are furthermore easier to insert into the Spitzer observing schedule. We present our pilot study from this program using the exoplanet WASP-14b. Data of this system were taken both as a sparsely sampled phase curve as well as a staring-mode phase curve. Both data sets, as well as snapshot-style observations of a calibration star, are used to validate this technique. By fitting our WASP-14b phase snapshot data set, we successfully recover physical parameters for the transit and eclipse depths as well as the amplitude and maximum and minimum of the phase curve shape of this slightly eccentric hot Jupiter. We place a limit on the potential phase to phase variation of these parameters since our data are taken over many phases over the course of a year. We see no evidence for eclipse depth variations compared to other published WASP-14b eclipse depths over a 3.5 year baseline.
Complexité de l’accueil des nouvelles parentalités en maternité
Authors: Dorso Marie-Émilie , Teissier Emmanuelle 
Published: June 2016

Cet article illustre des expériences autour des nouvelles formes de parentalité au sein d’une maternité. Il dresse un état des lieux non exhaustif de ces situations « atypiques », soulignant toute la complexité de ces nouveaux types de filiation et les questions qui se posent pour le devenir de l’enfant et de sa famille.
« Papa, Maman, bobos… »
Authors: Rajablat Marie , de Truchis-Ramière Vésiane 
Published: June 2016

L’unité Esquirol est une unité d’hospitalisation à temps complet pour enfants et adolescents. Notre travail inclut une juste et nécessaire proximité avec les familles. Pour ces jeunes patients, famille rime avec famille d’origine, famille recomposée, décomposée, adoption, famille d’accueil, services sociaux, etc. Alors comment transformer l’accueil de ces jeunes et leurs parents en une rencontre nouvelle et créatrice où chacun a une place et où la proximité des êtres devient moins insoutenable ?
Les pionniers de la participation au Maroc. Espace de reclassement et constitution d’un savoir autonome
Authors: Cheynis Éric 
Published: June 2016

Cet article est consacré aux agents qui fondent leur position sur l’élaboration, la promotion et la mise en œuvre, au Maroc, de la participation, afin d’en écarter toute approche téléologique, ou diffusionniste et désincarnée car sans acteur. Il porte sur une période particulière – la décennie au tournant du xx e siècle – avant que ne s’institutionnalisent des dispositifs, des pratiques et des rôles. Dans ce contexte, il met au jour le rôle d’intermédiaires qui ont contribué à importer au Maroc la participation tout en s’imposant comme des experts de cette dernière. L’analyse aborde la participation comme un espace de reclassement social et professionnel et spécifie les compétences nécessaires à une « entrée en expertise » : expériences professionnelles antérieures, connaissances du terrain, savoirs académiques mais aussi passé militant. Au final, l’article met en relation deux histoires à l’origine de l’invention de positions sociales nouvelles : celle de rôles et de postes en train de se faire et liée à une offre de participation de la part de bailleurs étrangers et celle des hommes et des femmes qui les occupent.
Donner la parole aux étrangers ? De la création d’une participation politique à l’usage ethnicisé de la catégorie d’« étranger » par les municipalités
Authors: Flamant Anouk 
Published: June 2016

Cet article s’intéresse à deux conseils de résidents étrangers existants dans les villes de Nantes et de Strasbourg dans les années 2000. Il questionne l’usage paradoxal de la catégorie d’« étranger » par les pouvoirs publics. En premier lieu, cet article permet de comprendre comment une citoyenneté territoriale est définie par l’intermédiaire de ces instances participatives. Ensuite, il révèle le fait que la distinction entre « national » et « étranger » est inadéquate pour comprendre quelle est la population ciblée par ces conseils. Ainsi, cet article démontre comment les villes ont recours à des critères ethniques au sein de la République française pour définir le public de leurs politiques d’intégration et de lutte contre les discriminations. Finalement, cet article vise à comprendre l’utilisation de critères ethniques dans les politiques publiques françaises.
La Turquie en quête d’un nouveau positionnement au Moyen-Orient
Authors: Marcou Jean 
Published: June 2016

Avant les révoltes arabes de 2011, la Turquie apparaissait comme une puissance régionale ambitieuse, accumulant les succès diplomatiques. La déstabilisation du Moyen-Orient a remis en cause cette dynamique positive. Le positionnement d’Ankara dans le conflit syrien est loin d’être clair. Ses ambiguïtés à l’égard des djihadistes ont suscité méfiance et tensions. Les relations d’Ankara avec Moscou, Téhéran et Le Caire sont au plus bas, tandis qu’un rapprochement avec Riyad est amorcé.
HMBPP Analog Prodrugs Bypass Energy-Dependent Uptake To Promote Efficient BTN3A1-Mediated Malignant Cell Lysis by Vγ9Vδ2 T Lymphocyte Effectors
Authors: Kilcollins Ashley M. , Li Jin , Hsiao Chia-Hung Christine , Wiemer Andrew J. 
Published: June 2016

Abstract
Vγ9Vδ2 effector T cells lyse cells in response to phosphorus-containing small molecules, providing primates a unique route to remove infected or malignant cells. Yet, the triggering mechanisms remain ill defined. We examined lysis mediated by human Vγ9Vδ2 effector T cells in response to the naturally occurring (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate (HMBPP) or a synthetic cell-permeable prodrug, bis (pivaloyloxymethyl) (E)-4-hydroxy-3-methyl-but-2-enyl phosphonate. CD27+/CD45RA− Th1-like effector cells killed K562 target cells through a mechanism that could be enhanced by either compound or TCR Ab and blocked by Src inhibition or butyrophilin 3 isoform A1 (BTN3A1) disruption. Pretreatment at 4°C decreased HMBPP-induced lysis but did not reduce lysis induced by bis (pivaloyloxymethyl) (E)-4-hydroxy-3-methyl-but-2-enyl phosphonate. Together, our results show that internalization of HMBPP into target cells is required for BTN3A1-dependent lysis by Vγ9Vδ2 effector T cells. The enhanced activity of the prodrug analog is due to its ability to bypass the pathways required for entry of HMBPP. These findings support an inside-out model of T cell triggering driven by small-molecule induction of BTN3A1.