bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Erythromycin on Orocecal Transit Time in Normal Healthy Male Subjects: A Double‐Blind, Placebo Controlled Study
Authors: Minocha Anil , Gallo Steven H 
Published: March 2016

OBJECTIVE: To investigate the effect of erythromycin on orocecal transit time (OCTT) in 17 healthy male subjects in a double‐blind, placebo controlled crossover trial.SUBJECTS AND METHODS: After an overnight fast, each subject received 250 mg erythromycin base, 500 mg erythromycin base or placebo on three different days. A standardized breakfast meal plus 20 g lactulose was administered 30 mins after ingestion of the test dose. Exhaled breath was collected and hydrogen concentration was assessed over 4 h. Hydrogen concentrations over time for each session were analyzed by a generalized logistic function generating a sigmoidal curve. The ‘front’ transit time (T1) was taken as the time when a sustained rise in breath hydrogen concentration was first observed. The midpoint from baseline to peak hydrogen concentration was denoted T2 and represented the time when approximately half of the test meal had reached the cecum.RESULTS: There was no effect of erythromycin on OCTT. The T1 (mean ± SEM) was 103.2±11.2, 103.3± 15.3 and 70.9±15.9 mins for placebo, 250 mg erythromycin base and 500 mg erythromycin base, respectively (P>0.05). Similarly, the T2 was 113.3±11.3, 113.9± 16.5 and 99.3±15.3 mins for the three regimens.CONCLUSIONS: Oral administration of erythromycin does not alter OCTT in healthy male subjects.
Duodenal Ulcer and Helicobacter pylori Infection at High Altitude: Experience from Southern Saudi Arabia
Authors: Ahmed M El Bagir K , Al-Knawy BA , Al-Wabel AH , Foli AK 
Published: March 2016

OBJECTIVE: To study the clinical presentation, endoscopic features and prevalence of Helicobacter pylori in duodenal ulcer (DU) patients in southern Saudi Arabia, located 3150 m above sea level, and to compare results with those from low altitude regions of the Kingdom.METHODS: Prospective study of patients with proven DU referred for upper gastrointestinal endoscopy at Asir Central Hospital, Abha, southern Saudi Arabia over an 18‐month period.RESULTS: Of 126 patients with proven DU, 72% were men and mean age was 40.4 years (range 18 to 68). Twenty‐eight per cent were smokers and only 5% used nonsteroidal anti‐inflammatory drugs. Thirty‐eight patients (30%) presented with hematemesis or melena, and the majority had a single ulcer. Nineteen per cent of patients with dyspepsia had DU and 96% had H pylori. These results are comparable with those reported from the low altitude, warmer regions of Saudi Arabia.CONCLUSIONS: Age of patients and the male:female ratio were similar to those in developing countries. The frequency of smoking is lower than in western countries and no patient in this report consumed alcohol. High altitude did not affect the prevalence of DU or the frequency of H pylori because the results were comparable with those from the low altitude areas of the Kingdom of Saudi Arabia and other lowland developing countries. Although great socioeconomic changes have increased the incidence of heart disease, the patterns of DU and H pylori infection assume those in developing nations.
Patients’ Diets and Preferences in a Pediatric Population with Inflammatory Bowel Disease
Authors: Green Timothy J , Issenman Robert M , Jacobson Kevan 
Published: March 2016

PURPOSE: To determine the dietary practices of the pediatric inflammatory bowel disease population at the Children's Hospital of the Hamilton Health Sciences Corporation and the reported effectiveness of those diets.PATIENTS AND METHODS: A questionnaire mailed to 153 pediatric patients was returned by 125 patients (76 Crohn's disease [CD] and 49 ulcerative colitis [UC] patients) - an 82% response rate.RESULTS: The median age of respondents was 13 years, and 62% were male. Ninety per cent and 71% of CD and UC patients, respectively, had changed their diets since diagnosis. Caloric supplements (eg, BOOST [Mead Johnson Nutritionals]), sole source nutrition, low fibre and lactose-free diets were used by more than 15% of CD patients, whereas lactose-free, nonspicy, low acid, additive-free, caloric supplement and low fibre diets were used by more than 15% of UC patients. A diet supplement was more commonly used in CD patients (P<0.05) and an additive-free diet in UC patients. Corn and corn products, nuts, milk and bran were avoided by more than 20% of CD and UC patients; however, more CD than UC patients avoided corn and corn products. In addition, UC patients (more than 20%) also avoided tomato, other dairy (nonfluid milk-based products and foods containing milk products), chocolate, cheese, wheat, tomato sauces and fruit juice. A benefit was reported for 103 of 141 reported diets, with the most commonly alleviated symptoms being abdominal pain, diarrhea and flatulence.CONCLUSION: Many children with inflammatory bowel disease have altered their diets to manage their disease and have attributed symptomatic relief to these diets.
Implementing Dynamically Evolvable Communication with Embedded Systems through WEB Services
Authors: Jammalamadaka Sasi Bhanu , A Vinaya Babu , A Trimurthy 
Published: March 2016

<p>Embedded systems that monitor and control safety and mission critical system are communicated with by a HOST located at a remote location through Internet. Such kind of embedded systems are developed to be dynamically evolvable with respect to syntax, semantics, online testing and communication subsystems. All these systems are to be dynamically evolvable and the components needed for evolution are also to be added into the embedded system. Architectural models describe various components using which dynamically evolvable sub-systems are realised through implementation by using specific and related technologies. Implementation system describe the platform, code units and the interlacing of various processes/tasks to the elementary level of details. WEB services place an excellent platform for implementing dynamically evolvable systems due to the use of open standards.</p><p> </p><p>This paper presents an implementation system that is related to dynamically evolvable communication and other sub-systems using web services technologies.</p>
Predictable Models and Experimental Measurements for Electric Properties of Polypropylene Nanocomposite Films
Authors: Thabet Ahmed , Mobarak Youssef A. 
Published: March 2016

<span>This paper processed and characterized cost-fewer polypropylene (PP) nanocomposite films; an experimental work has been investigated for studying the electric properties of the new nanocomposite materials and compared with unfilled industrial materials in a frequency range up to 1 kHz. A small addition of nanoparticles (clay, and fumed silica) to polypropylene showed appreciable improvement in the electric reactance and conductance at different frequency up to 1kHz, in addition, an electric spectroscopy has been measured the electric properties of polypropylene with and without nanoparticles under variant temperatures (20°C, and 60°C). Cambridge Engineering Selector (CES) program were carried out the electrical/mechanical predictable models for the suggested materials. Finally, this paper leads to synthesize electrical insulating polypropylene nanocomposite films where the electrical properties are properly maintained in order to achieve more cost-effective, energy-effective and hence environmentally better materials for the electrical insulation technology.</span>
Novel ROADM modelling with WSS and OBS to Improve Routing Performance in Optical Network
Authors: G.R. Kavitha G.R , T.S. Indumathi 
Published: March 2016

The area of optical network is on constant point of focus among the research communities owing to potential advantage of long distance communication as well as the routing issues associated with it. Majority of the implemented techniques calls for using expensive hardware or adopting narrowed technical assumptions, for which reason the routing performance couldn’t be optimized to a large extent. The present manuscript proposes a novel technique called as Optimized Routing for Peak Traffic under the scenario of uncertainties in the existing traffic scenario. The proposed solution presents some potential principle that is incorporated in the ROADM design for enhancing the capabilities of the proposed system. The system is evaluated under multiple scenarios of analysis using blocking probabilities, OSNR, bit error rate, iteration etc. The outcome of the proposed system is compared with the one of the existing significant study to benchmark it.
High Performance Control of Grid Connected Cascaded H-Bridge Active Rectifier Based on Type II-Fuzzy Logic Controller with Low Frequency Modulation Technique
Authors: Dabbaghjamanesh M. , Moeini A. , Ashkaboosi M. , Khazaei P. , Mirzapalangi K. 
Published: March 2016

This paper tries to employ a fuzzy logic (FL) controller type II to control the Cascaded H-Bridge (CHB) active rectifier. This controller has strong performance, specially, when a low switching frequency Selective Harmonic Elimination (SHE) method is used. In order to regulate all of the DC link voltages, the optimum voltage balancing strategy in the low frequency modulation technique is used in the proposed method. Finally, the performance and effectiveness of the proposed method is validated in MATLAB environment. All the simulation and result has been simulated by MATLAB software.
Design of Three-Phase Three-Switch Buck-Type Rectifier for Pre-Charging Application
Authors: S Anandh , S Vijayan , Paramasivam Paramasivam 
Published: March 2016

The main objective of a pre-charging circuit in variable frequency drives is to pre-charge the DC-bus capacitor without any voltage and current overshoot within the specified time. In exisiting variable frequency drives seperte pre-charging circuits (or) thyristor bridges were used due to this drives power density, cost becomes high and control technique becomes complex. This paper presents about the design of three-phase three-switch buck-type rectifier for pre-charging application used in variable frequency drives which elimates the disadvantages of existing techniques. In this paper we will discuss about design procedure of pre-charging circuit of an 800KW converter with dc-link output voltage of 775V at an input ac voltage of 550V, 60Hz, selection of power and passive components, voltage and current stress of power transistors. In the final this paper discusses about loss distribution of the components and comparison of new converter technique with existing pre-charging techniques.
Technical and Economic Evaluation of Hybrid wind/PV/Battery Systems for Off-Grid Areas using HOMER Software
Authors: Gheiratmand Alireza , Effatnejad Reza , Hedayati Mahdi 
Published: March 2016

Incremental consumption of electrical energy, reduction of fossil fuel resources and environmental pollution problems caused by them are the main reasons, which tend the managers and officials in countries energy sector to develop use of renewable systems. In the not-too-distant future the use of renewable energy such as wind and solar will be very important and will play predominant role in economic indices of power systems. In recent years, technological advances in renewable energy and increasing price of petroleum products promote system managers to use low-cost and low-emission energy resources in form of hybrid systems and widespread propagation of electricity generation have been developed in remote areas. In Hybrid systems two or more sources of renewable energy is typically adopted, which increases the reliability of these systems. In this paper, the technical and economical consideration of a wind and solar hybrid system to supply electrical energy for a number of remote users (aid and medical emergency Shelter in Yazd) is provided. In order to investigate optimization and economic analysis of the proposed hybrid system, the HOMER software is used. The results of Simulation in HOMER software show that Solar cells and wind systems with average generation power of 896 kWh/yr. and 343 kWh/yr., consist proportion of 72 and 28 percent of the total generated energy respectively, which are dedicated to satisfy the loads
Close Loop V/F Control of Voltage Source Inverter using Sinusoidal PWM, Third Harmonic Injection PWM and Space Vector PWM Method for Induction Motor
Authors: Ojha Sandeep , Pandey Ashok Kumar 
Published: March 2016

<p>The aim of this paper to presents a comparative analysis of Voltage Source Inverter using Sinusoidal Pulse Width Modulation Method, Third Harmonic Injection Pulse Width Modulation Method and Space Vector Pulse Width Modulation Two level inverter for Induction Motor. In this paper we have designed the Simulink model of Inverter for different technique. An above technique is used to reduce the Total Harmonic Distortion (THD) on the AC side of the Inverter. The Simulink model is close loop. Results are analyzed using Fast Fourier Transformation (FFT) which is for analysis of the Total Harmonic Distortion. All simulation are performed in the MATLAB Simulink / Simulink environment of MATLAB.</p>
Development of Class D Inverter for Acoustics Energy Transfer Implantable Devices
Authors: Husin Siti Huzaimah , Md Saat Mohd Shakir , Yusop Yusmarnita , Abdul Ghani Zamre , Nguang Sing Kiong 
Published: March 2016

The working principle of half-bridde Class D Parallel-Resonant Inverter (PRI) as power amplifier is presented in this paper. Simulation of the model is carried out using Proteus. In order to verify the simulation results, an experimental verification is done. This inverter is used to excite the PZT transducers at the suggested resonant frequency of 416 kHz with power level transferred through Acoustics Energy Transfer (AET) concept at about 80mW. As experimental outcome result, the system managed to transfer energy at 66mW to the receiver side.
The VWF-GPIb axis in ischaemic stroke: lessons from animal models
Authors: Denorme Frederik , De Meyer Simon F. 
Published: March 2016

SummaryStroke is a leading cause of death and long-term disability worldwide. Ischaemic stroke is caused by a blood clot that obstructs cerebral blood flow. Current treatment mainly consists of achieving fast reperfusion, either via pharmacological thrombolysis using tissue plasminogen activator or via endovascular thrombectomy. Unfortunately, reperfusion therapy is only available to a limited group of patients and reperfusion injury can further aggravate brain damage. Hence, there is an urgent need for better understanding of ischaemic stroke pathophysiology in order to develop novel therapeutic strategies. In recent years, the pathophysiological importance of von Willebrand factor (VWF) in ischaemic stroke has become clear from both clinical and experimental studies. In particular, binding of VWF to platelet glycoprotein Ib (GPIb) has become an interesting target for ischaemic stroke therapy. Recent insights show that inhibting the VWF-GPIb interaction could result in a pro-thrombolytic activity improving cerebral reperfusion rates and concurrently reducing cerebral ischaemia/reperfusion damage. This review gives an overview of the experimental evidence that illustrates the crucial role of the VWF-GPIb axis in ischaemic stroke.
Русский Экзистенциализм: Достоевский – Бкрдяев [Russian Existentialism: Dostoevsky – Berdyaev]
Authors: Сердюкова Елена 
Published: March 2016

В статье анализируется становление экзистенциализма в России в кон- тексте творчества Достоевского и Бердяева. Внимание акцентируется на формирование экзистенциального мироощущения Бердяева, в центре учения которого находится понимание личности как духа, как существо- вания. Для Бердяева Достоевский предстает как «великий антрополог», которого интересует человек, отпущенный на свободу. Бердяев заявляет об экзистенциальном характере всей русской философии и видит в До- стоевском предтечу русского экзистенциализма.
[The paper shows the evolution of Existentialism in Russia in the context of Dostoevsky’s and Berdyaev’s work. The focus is on Berdyaev’s Existentialist sensibility, which centres on the concept of the individual as spirit, as existence. For Berdyaev, Dostoevsky is the “great anthropologist,” who is interested in Man released into freedom. Berdyaev points to the existentialist character of the whole of Russian philosophy and identifies Dostoevsky as the precursor of Russian Existentialism.]
A new proof of a theorem of Hubbard and Oberste-Vorth
Authors: Radu Remus , Tanase Raluca 
Published: March 2016

AbstractWe give a new proof of a theorem of Hubbard and Oberste-Vorth (Real and Complex Dynamical Systems, pp. 89-132, 1995) for Hénon maps that are perturbations of a hyperbolic polynomial and obtain the Julia set $J^{+}$

J
+

inside a polydisk as the image of the fixed point of a contracting operator. We also give different characterizations of the Julia sets J and $J^{+}$

J
+

which prove useful for later applications.
Optimal coincidence point results in partially ordered non-Archimedean fuzzy metric spaces
Authors: Abbas Mujahid , Saleem Naeem , De la Sen Manuel 
Published: March 2016

AbstractIn this paper, we introduce best proximal contractions in complete ordered non-Archimedean fuzzy metric space and obtain some proximal results. The obtained results unify, extend, and generalize some comparable results in the existing literature.
Diagnostics of ulcus cruris venosum
Authors: Pljakic A. , Dörler M. , Stücker M. 
Published: March 2016

SummaryClinical diagnostics of venous leg ulcers set the course for efficient therapy. Precise clinical findings with an objectification of signs and symptoms of chronic venous insufficiency are essential. Duplex ultrasound investigations of the leg veins are necessary in the very early stages after the appearance of leg ulcers. Furthermore, not only a clinical investigation of the arterial perfusion but also the determination of the ankle-brachial-index is obligatory. Microbiological diagnostics are currently seen as useful in Germany, due to discussions on MRSA, even though they don´t have an immediate therapeutic consequence without the presence of clinical signs of infection. Therapeutic achievements can be objectified by a continuous documentation of the wound size, the wound bed, the wound exudate and signs of infection as well as the life quality of patients with chronic wounds.
Marine Omega3 wound matrix for the treatment of complicated wounds
Authors: Trinh T. T. , Dünschede F. , Vahl C.-F. , Dorweiler B. 
Published: March 2016

Summary
Introduction Complicated wounds in the lower extremity can arise as a consequence of insufficient soft-tissue coverage after amputations in diabetic patients. The Kerecis® Omega3 wound matrix is a decellularized skin matrix derived from codfish and represents an alternative treatment option to achieve wound healing.
Methods 5 patients with diabetes mellitus and complicated wounds in the lower limb with exposed bony segments were treated with the Omega3 wound matrix between November 2014 and November 2015. Following initial debridement in the operating room, the wound matrix was applied and covered with a silicone mesh. In the further course, wound treatment was conducted on outpatient setting.
Results In total, 7 wounds were treated with localization at the level of the thigh (n=2) and the forefoot (n=5). For the wounds at the thigh, it took 26 weeks to achieve wound closure, whereas the wounds at the level of the forefoot showed healing times between 13 and 41 weeks. In all patients, a reduction of analgetics intake was noted when the treatment with the Omega3 wound matrix was initiated.
Conclusion The Kerecis® Omega3 wound matrix represents a viable treatment option in complicated wounds in the lower limb of diabetic patients to circumvent an otherwise necessary proximalization of amputation level. Further studies comparing the Omega3 wound matrix with appropriate control groups of standard therapies for soft-tissue conditioning/coverage like negative pressure therapy, biosurgery and other acellular dermal matrices are warranted.
Licensing Contracts: Control Rights, Options, and Timing
Authors: Crama Pascale , De Reyck Bert , Taneri Niyazi 
Published: March 2016

Research and development (R&D) collaborations, common in high-tech industries, are challenging to manage because of technical and market risks as well as incentive problems. We investigate how control rights, options, payment terms, and timing allow the innovator to capture maximum value from its R&D collaborations with a marketer. Our study reveals a counterintuitive result; the innovator may, under certain conditions, prefer to grant launch control rights or buyout options to the marketer despite the fact that both terms restrict its downstream actions. We demonstrate that a menu of contracts is not necessary to address the adverse selection problem because the menu can be replicated by a single option contract. We show that timing, through renegotiation or delayed contracting, as well as the careful allocation of control rights and options can have a significant influence on the value of collaborative R&D. We provide recommendations on the optimal contract structure and timing based on two project characteristics, novelty of the R&D process and market-potential variability. This paper was accepted by David Hsu, entrepreneurship and innovation.
Waist circumference in coronary heart disease versus type-two diabetes
Authors: Shi Wendan , Neubeck Lis , Gallagher Robyn 
Published: March 2016

Obesity-related chronic illness is an international health issue. Waist circumference can assess central adiposity, which is strongly associated with cardiovascular disease and type two diabetes mellitus. Aim: This study evaluates the effectiveness of waist circumference in comparison to body mass index as measured at different locations in adults with cardiovascular disease or type two diabetes mellitus, and responsiveness of these measures to weight change. Results: All measures were significantly correlated with body mass index (r>0.80), with the strongest correlations measured at midline between lowest rib and top of iliac crest in females (r=0.89), and measured at widest level for males (r=0.83). All sites were accurate in detecting high cardiovascular disease risk (AUC>0.80). The site most responsive to weight change was at midline in females and at narrowest level in males. Conclusion: A general protocol for waist circumference should be established for assessing visceral fat, predicting cardiovascular disease risks and monitoring weight change.