bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions of ‘physical activity’ and ‘exercise’ among people living with HIV: A qualitative study
Authors: Vader Kyle , Simonik Alya , Ellis Denine , Kesbian Dirouhi , Leung Priscilla , Jachyra Patrick , Carusone Soo Chan , O'Brien Kelly K 
Published: November 2017

Background/Aims: Many people living with HIV do not engage in regular physical activity and it is unclear how perceptions of physical activity and exercise influence participation. Our aim was to explore individual perceptions of physical activity and exercise in people living with HIV. Methods: We conducted a descriptive qualitative study using face-to-face semi-structured interviews. We recruited adults who self-identified as living with HIV from a speciality hospital in Toronto, Canada. Interviews were audio-recorded, transcribed verbatim, and analysed using thematic analysis. Findings: A total of 14 participants with a median age of 50 years participated in the study. Four themes (and subsequent sub-themes) emerged relating to physical activity and exercise. These included: (1) perceptions of physical activity and exercise (seeing them as a continuum of activity, as a health-promoting behaviour, and that they ‘should’ be a greater priority); (2) benefits (restores physical function, improves mental health, and prevents isolation); (3) risks (physical injury, pain, and fear of ‘overdoing it’); and (4) recommendations for engagement (education, graded activity, and an individualised approach). Conclusions: Findings suggest health care professionals should consider exploring perceptions of physical activity and exercise among people living with HIV to ensure physical activity interventions are individualised to meet their diverse health and wellbeing needs.
Who Helps? Characteristics and Correlates of Informal Supporters to Adults With Disabilities
Authors: Sanderson Kelli A. , Burke Meghan M. , Urbano Richard C. , Arnold Catherine K. , Hodapp Robert M. 
Published: November 2017

Abstract
This study examined who provides informal (or unpaid) supports to people with intellectual and developmental disabilities (IDD). Participants included 657 adult siblings of people with disabilities who responded to a national survey about informal supports in the areas of recreation, employment, and housing. Results indicated that most people with IDD received informal supports, with parents and sibling respondents most often providing those supports. Support was most commonly received in recreation, as opposed to housing or employment. Asked to list nonfamily informal supporters, respondents often mentioned paid staff and disability organizations. Correlates of total numbers of informal supporters included the individual with disability's functioning level and parents' ability to care for their offspring with disabilities.
The Feasibility of Group Video Conferencing for Promotion of Physical Activity in Adolescents With Intellectual and Developmental Disabilities
Authors: Ptomey Lauren T. , Willis Erik A. , Greene J. Leon , Danon Jessica C. , Chumley Tara K. , Washburn Richard A. , Donnelly Joseph E. 
Published: November 2017

Abstract
Physical activity (PA) rates of adolescents with intellectual and developmental disabilities (IDD) are low and effective strategies for increasing PA are limited. The purpose of this study was to assess the feasibility of a group-based PA intervention that was delivered remotely to adolescents with IDD. Participants attended 30-min group PA sessions 3 times a week. PA sessions were delivered in their homes by video conferencing on a tablet computer. Thirty-one participants enrolled and 29 completed the 12-week intervention. Participants attended 77.2% ± 20.8% of scheduled sessions and averaged 26.7 ± 2.8 min of PA/session, with 11.8 ± 4.8 min at moderate- to vigorous intensity. Group-based PA delivered remotely may be a feasible approach for the promotion of PA in adolescents with IDD.
Leukocyte Counts Based on DNA Methylation at Individual Cytosines
Authors: Frobel Joana , Božić Tanja , Lenz Michael , Uciechowski Peter , Han Yang , Herwartz Reinhild , Strathmann Klaus , Isfort Susanne , Panse Jens , Esser André , Birkhofer Carina , Gerstenmaier Uwe , Kraus Thomas , Rink Lothar , Koschmieder Steffen , Wagner Wolfgang 
Published: November 2017

Abstract

BACKGROUND
White blood cell counts are routinely measured with automated hematology analyzers, by flow cytometry, or by manual counting. Here, we introduce an alternative approach based on DNA methylation (DNAm) at individual CG dinucleotides (CpGs).

METHODS
We identified candidate CpGs that were nonmethylated in specific leukocyte subsets. DNAm levels (ranging from 0% to 100%) were analyzed by pyrosequencing and implemented into deconvolution algorithms to determine the relative composition of leukocytes. For absolute quantification of cell numbers, samples were supplemented with a nonmethylated reference DNA.

RESULTS
Conventional blood counts correlated with DNAm at individual CpGs for granulocytes (r = −0.91), lymphocytes (r = −0.91), monocytes (r = −0.74), natural killer (NK) cells (r = −0.30), T cells (r = −0.73), CD4+ T cells (r = −0.41), CD8+ T cells (r = −0.88), and B cells (r = −0.66). Combination of these DNAm measurements into the “Epi-Blood-Count” provided similar precision as conventional methods in various independent validation sets. The method was also applicable to blood samples that were stored at 4 °C for 7 days or at −20 °C for 3 months. Furthermore, absolute cell numbers could be determined in frozen blood samples upon addition of a reference DNA, and the results correlated with measurements of automated analyzers in fresh aliquots (r = 0.84).

CONCLUSIONS
White blood cell counts can be reliably determined by site-specific DNAm analysis. This approach is applicable to very small blood volumes and frozen samples, and it allows for more standardized and cost-effective analysis in clinical application.
Debtors, creditors, and sovereign money: A case for institutional blending and the amalgamated mind
Authors: Oakley Todd 
Published: November 2017

AbstractMuch social cognition and action is dialogical in nature and profitably understood from a second-person perspective. The elemental social roles of “debtor” and “creditor” are of great importance in explaining the structure and history of a wide range of social facts and institutions. Yet these person-level experiences of indebtedness and the mental spaces they engender are not sufficient to account for complex social facts. Sovereign money systems are a leading example where our person-level experiences of exchange lead us astray by actively hindering our ability to grasp money’s macroeconomic functions. This article provides a comprehensive account of money as a distributed cognitive phenomenon. It summarizes and critiques a prior analysis of money as a conceptual blend enabling
Poly(N-isopropylacrylamide)-coated gold nanorods mediated by thiolated chitosan layer: thermo-pH responsiveness and optical properties
Authors: Esquivel Reynaldo , Canale Iván , Ramirez Maricela , Hernández Pedro , Zavala-Rivera Paul , Álvarez-Ramos Enrique , Lucero-Acuña Armando 
Published: November 2017

AbstractA core-shell of colloidal metal-responsive polymer provides an innovative model in functional materials. These core-shell nanocomposites offer the possibility to control some properties, such as particle size, surface plasmon resonance and morphology. In this research, we demonstrate the successful synthesis and functionality of gold nanorods (GNR) coated with the polymers chitosan (Ch) and poly(N-isopropylacrylamide) (PNIPAM). The polymer coatings are performed using a two-step method. First, GNR were coated with a thiolated chitosan (GNR-Ch) by replacing hexadecyltrimethylammonium bromide with a chitosan thiomer. Structural modification of GNR-Ch was monitored by Fourier transform infrared spectroscopy. Then a second polymeric coating was done by in situ free radical polymerization of N-isopropylacrylamide (NIPAM) on GNR-Ch to obtain the nanocomposite GNR-Ch-PNIPAM. The nanocomposite average size was analyzed by dynamic light scattering. The evolution of ζ potentials during the coatings was measured using electrophoretic mobility. GNR-Ch-PNIPAM presented a collapsed structure when heated above the lower critical solution temperature. The particle size of GNR-Ch-PNIPAM was manipulated by changing the pH. Plasmonic properties were evaluated by UV-Vis spectroscopy. Results showed an important blue shift due to the PNIPAM coating thickness. Thermo- and pH-responsive properties of the nanocomposite GNR-Ch-PNIPAM could be used as a drug delivery system.
One-pot synthesis of benzopyrans catalyzed by silica supported dual acidic ionic liquid under solvent-free conditions
Authors: Zhang Qiang , Wei Huaixin , Li Jihang , Zhao Xin , Luo Jun 
Published: November 2017

Abstract
A mild and efficient method was developed for the preparation of tetrahydrobenzo[b]pyrans through a one-pot three-component condensation of aldehydes, malononitrile and dimedone in the presence of silica supported dual acidic ionic liquid (DAIL@SiO2) as a powerful catalyst under solvent-free conditions. This procedure is characterized by mild reaction conditions, simple workup and environmental friendliness. Moreover, the catalyst could be recycled for five times with only a slight loss of catalytic activity.
Enterobiasis epidemiology and molecular characterization of Enterobius vermicularis in healthy children in north-eastern Poland
Authors: Kubiak K. , Dzika E. , Paukszto Ł. 
Published: November 2017

Summary
Enterobiasis is a human intestinal parasitic disease caused by human pinworm, Enterobius vermicularis. Despite being the most prevalent nematode infection in Europe and North America, predominantly among in school aged children, the data concerning infection rate and knowledge of genetic variability of pinworms are incomplete. The aim of the study was the estimation of prevalence and molecular typing of Enterobius vermicularis among healthy children in north-eastern Poland. In 2013 – 2015, 296 individuals (aged 2 – 18 years) from 12 kindergartens, schools and orphanages were examined by the adhesive cellophane tape method. Data on socio-demographic status were collected using a questionnaire. Molecular analysis was performed using the DNA of adult female pinworms and primers targeting the region of cytochrome oxidase I gene. The overall prevalence of enterobiasis was 10.1 %. Enterobius vermicularis infection rates were 3.9 % in children living in families and 32.8 % among the orphans (OR=0.08; 95 % CI: 0.04 – 0.19; p<0.001). There were no associations between distribution of enterobiasis and gender, pets possession and the season of examination. In 43.3 % of the infected children enterobiasis was asymptomatic. Based on a molecular marker three different haplotypes of pinworm were identified. All sequences clustered within type B, together with human E. vermicularis isolates from Denmark, Germany, Greece, and Japan. This paper provides complementary data on the occurrence and intraspecific variability of E. vermicularis in human population in Europe.
Endoscopic treatment of early colorectal cancer – just a competition with surgery?
Authors: Ebigbo Alanna , Probst Andreas , Messmann Helmut 
Published: November 2017

AbstractThe endoscopic treatment of cancerous and precancerous lesions in the gastrointestinal (GI) tract has experienced major breakthroughs in the past years. Endoscopic mucosal resection (EMR) is a simple and efficient method for the treatment of most benign lesions in the GI tract. However, with the introduction of endoscopic submucosal dissection (ESD) and endoscopic full-thickness resection (EFTR), the scope of lesions eligible for endoscopic treatment has been widened significantly even in the colon. These methods are now being used routinely not just for the treatment of benign lesions but also in the curative en bloc resection of early colorectal cancers. The quick, efficient, and noninvasive character of these endoscopic procedures make them not just an alternative to surgery but, in many cases, the methods of choice for the treatment of most early colon cancers and some rectal cancers.
First-line antituberculosis drugs disrupt endocrine balance and induce ovarian and uterine oxidative stress in rats
Authors: Adebayo Olayinka A. , Adesanoye Omolola A. , Abolaji Olalekan A. , Kehinde Aderemi O. , Adaramoye Oluwatosin A. 
Published: November 2017

Abstract

Background:
The first-line antituberculosis (anti-TB) drugs, isoniazid (INH), rifampicin (RIF), ethambutol (EMB), and pyrazinamide (PZA), are effective in the treatment of pulmonary tuberculosis. However, the toxicity of these drugs in the clinical setting limits their use. Here, we evaluated the effects of anti-TB drugs on the reproductive system in female rats.

Methods:
Thirty-five female Wistar rats were assigned into five groups of seven animals each. The control group received normal saline, whereas others received INH (5 mg/kg), RIF (10 mg/kg), EMB (15 mg/kg), and PZA (15 mg/kg) through gavage thrice a week for 8 consecutive weeks.

Results:
Administration of anti-TB drugs significantly (p<0.05) reduced uterine and ovarian weight, as well as the relative weight of the uterus when compared with controls. In addition, anti-TB drugs increased the activities of alanine aminotransferase as well as the level of total bilirubin. Treatment with INH, RIF, and PZA significantly (p<0.05) reduced the levels of follicle-stimulating and luteinizing hormones, estrogen, and prolactin. The INH, RIF, EMB, and PZA caused significant (p<0.05) increases in uterine malondialdehyde (MDA) levels by 281%, 214%, 273% and 190%, respectively, whereas INH and EMB increased the ovarian malondialdehyde by 111% and 129%, respectively. These drugs significantly (p<0.05) decreased the activities of ovarian glutathione-S-transferase and uterine glutathione peroxidase, superoxide dismutase, and catalase. Histology revealed the erosion of uterine mucosa, debris in the lumen of the uterus, congestion, and underdeveloped follicles in ovaries.

Conclusions:
The first-line anti-TB drugs elicited reproductive toxicity in the uterus and ovaries of rats through mechanisms that involved oxidative stress.
On groups with formational subnormal Sylow subgroups
Authors: Monakhov Victor S. , Sokhor Irina L. 
Published: November 2017

Abstract
We investigate a finite group G with

𝔉

{\mathfrak{F}}

-subnormal Sylow subgroups,
where

𝔉

{\mathfrak{F}}

is a subgroup-closed formation and

𝔄
1

⁢
𝔄

⊆
𝔉
⊆

𝔑
⁢
𝒜

{\mathfrak{A}_{1}\mathfrak{A}\subseteq\mathfrak{F}\subseteq\mathfrak{N}%
\mathcal{A}}

.
We prove that G is soluble and the derived subgroup of each metanilpotent subgroup
is nilpotent. We also describe the structure of groups
in which every Sylow subgroup is

𝔉

{\mathfrak{F}}

-subnormal
or

𝔉

{\mathfrak{F}}

-abnormal.
Evaluating stress corrosion cracking behaviour of high strength AA7075-T651 aluminium alloy
Authors: Prabhuraj P. , Rajakumar S. , Lakshminarayanan A.K. , Balasubramanian V. 
Published: November 2017

AbstractThe objective of the present study is to determine the threshold stress level of stress corrosion cracking (SCC) in AA7075-T651 aluminium alloy by suitable experimentation. The test was carried out using a circumferential notch specimen in a horizontal-type constant load SCC setup in a 3.5 wt.% NaCl solution. The time to failure by SCC was determined at various loading conditions. The threshold stress of AA7075-T651 alloy was found to be 242 MPa in a 3.5 wt.% NaCl solution. The various regions of the fractured surface specimen such as machined notch, SCC region and final overload fracture area were examined using scanning electron microscopy (SEM) in order to identify the SCC mechanism.
Crystal structure of 1-(4-fluorophenyl)-N-(5-((triphenylstannyl)thio)thiophen-2-yl)methanimine, C27H20FN3S2Sn
Authors: Meng Fankun , Jia Junying , Liu Hongsheng 
Published: November 2017

Abstract
C27H20FN3S2Sn, monoclinic, P21/n (no. 14), a = 15.631(4) Å, b = 9.865(3) Å, c = 17.256(3) Å β = 108.335(11)°, V = 2525.8(10) Å3, Z = 4, R
gt(F) = 0.0398, wR
ref(F
2) = 0.0917, T = 298 K.
Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines
Authors: Stompor Monika , Świtalska Marta , Wietrzyk Joanna 
Published: November 2017

Abstract
The synthesis of hydroxyflavone derivatives is described. The acyl derivatives of 3-, 6-, 7-hydroxyflavones (compounds 2, 4, 6, respectively) and chrysin (5,7-dihydroxyflavone, 7) were obtained in high yields and evaluated in vitro for their cytotoxic activity against several cancer cell lines of different origin: MCF-7 (breast cancer), A549 (nonsmall cell lung cancer), MES-SA (uterine sarcoma), LoVo (colon cancer), drug-resistant human cancer cells (MES-SA/DX5, LoVo/DX) and also towards non-cancer cell line MCF-10A (normal breast epithelial cells). The flavones modified with acyl group showed higher antiproliferative activity than free hydroxyflavones. The highest activity was noted for 3-acetoxyflavone (2), which proved active against LoVo, LoVo/DX, and MES-SA cell lines (IC50 from 4.7 μM to 7.8 μM, respectively). The highest ability to overcome the barrier of resistance (resistance index=0.82) against the drug-resistant MES-SA/DX5 cells compared to the parental drug-sensitive MES-SA cell line was found for 7-acetoxyflavone (6).
A Sustainability Strategy Assessment Framework Model for Medical Tourism Supply Chain in Asia
Authors: Chung K.-C. , Chang L.-C. 
Published: November 2017

Abstract
This study developed a sustainability policy evaluation for medical tourism supply chain (MTSC) that is validated using the Delphi method and the analytical network process (ANP). This study assessed the criteria through expert survey method by five experts from the government, the academe, and the industry. Results showed that the financial perspective is the heaviest among the criteria, indicating unanimous agreement of the experts and scholars that a healthy financial situation is necessary to integrate the MTSC. This study can provide criteria and correct the overall performance for MTSC entrepreneurs and scholars. Lastly, the conclusion provided MTSC-related insights and suggestions.
Additive Phenotypes Underlie Epistasis of Fitness Effects
Authors: Sackman Andrew M , Rokyta Darin R 
Published: November 2017

Abstract
Gene interactions, or epistasis, play a large role in determining evolutionary outcomes. The ruggedness of fitness landscapes, and thus the predictability of evolution and the accessibility of high-fitness genotypes, is determined largely by the pervasiveness of epistasis and the degree of correlation between similar genotypes. We created all possible pairings of three sets of five beneficial first-step mutations fixed during adaptive walks under three different regimes: selection on growth rate alone, on growth rate and thermal stability, and on growth rate and pH stability. All 30 double-mutants displayed negative, antagonistic epistasis with regard to growth rate and fitness, but positive epistasis and additivity were common for the stability phenotypes. This suggested that biophysically simple phenotypes, such as capsid stability, may on average behave more additively than complex phenotypes like viral growth rate. Growth rate epistasis was also smaller in magnitude when the individual effects of single mutations were smaller. Significant sign epistasis, such that the effect of a mutation that is beneficial in the wild-type background is deleterious in combination with a second mutation, emerged more frequently in intragenic mutational pairings than in intergenic pairs, and was evident in nearly half of the double-mutants, indicating that the fitness landscape is moderately uncorrelated and of intermediate ruggedness. Together, our results indicated that mutations may interact additively with regard to phenotype when considered at a basic, biophysical level, but that epistasis arises as a result of pleiotropic interactions between the individual components of complex phenotypes and diminishing returns arising from intermediate phenotypic optima.
Reseña de: Los nuevos amos de la tierra: Land Grabbing (Liberti, 2015)
Authors: Ochoa Germán Ignacio 
Published: November 2017

Stefano Liberti. 2015. Los nuevos amos de la tierra. Land Grabbing. Bogotá: Penguin Random House Grupo Editorial. 250 pp. ISBN: 9788430616886. [Título original en italiano: Land Grabbing. Come il mercato delle terre crea il nuovo colonialismo].
Reseña de: Capitalism in the Web of Life: Ecology and Accumulation of Capital (Moore, 2015)
Authors: Palacio Germán 
Published: November 2017

Jason Moore. 2015. Capitalism in the Web of Life. Ecology and Accumulation of Capital [Capitalismo en la red de la vida. Ecología y acumulación de capital]. London  New York: Verso Books. 336 pp. ISBN 978-1781689028.
Reseña de: Guardianes de la selva o La odisea del gobierno propio y de la autonomía amazónica (von Hildebrand y Brackelaire, 2012)
Authors: Chapuis Oceane 
Published: November 2017

Martin von Hildebrand & Vincent Brackelaire. 2012. Guardianes de la selva. Gobernabilidad y autonomía en la Amazonia colombiana. Bogotá: GAIA. 248 pp. ISBN: 9789589773062.
La perpetuación del comportamiento antisocial de los jóvenes caboverdianos: un estudio predictivo
Authors: Dias Jorge , Formiga Nilton , Gonçalves Rui Abrunhosa , Cunha Olga , Conde Rita 
Published: November 2017

En Cabo Verde, desde finales de los años 90, se asiste a un creciente aumento del comportamiento antisocial de los jóvenes con edades comprendidas entre los 12 y los 21 años. Sin embargo, el conocimiento de los factores que causan y perpetúan tal comportamiento es aún muy incipiente. Este estudio busca identificar los factores que pueden predecir el comportamiento antisocial reportado en Cabo Verde, utilizando para tal fin, el International Self-Report Delinquency Study -3, (ISRD-3). La muestra estuvo constituida por 535 estudiantes de ambos sexos que asisten a la escuela pública en Cabo Verde, siendo 284 (53%) del sexo femenino y 247 (46.25%) del sexo masculino. La edad de los jóvenes varía entre los 13 y los 21 años, con una media de edad de 16.66 y una desviación estándar de 2.04. Los resultados indican que el sexo es un fuerte predictor de la perpetración de comportamientos antisociales, siendo que los individuos del sexo masculino revelan una mayor probabilidad de involucrarse en comportamientos antisociales. Los adolescentes con menos actitudes antisociales son también los que tienen menores probabilidades de envolverse en comportamientos antisociales. Del mismo modo, aunque sólo se revele marginalmente significativa, los adolescentes que relatan una mayor implicación en actividades antisociales se muestran más propensos a ocupar su tiempo libre en actividades perjudiciales. Estos resultados son analizados en términos de sus implicaciones para la prevención de la delincuencia.