bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lipodermatosclerosis and Pulmonary Hypertension in Systemic Sclerosis
Authors: Davuluri Srijana , Kapoor Puneet , Nandyala Swarna , Li Shufeng , Simard Julia , Lewis Matthew , Fiorentino David , Chung Lorinda 
Published: October 2024

ImportanceLipodermatosclerosis (LDS) stems from vascular dysfunction and dermal inflammation and thereby is mechanistically similar to systemic sclerosis (SSc). The association of LDS with SSc in the clinical setting has not been well characterized in the literature.ObjectiveTo evaluate the prevalence of LDS in SSc and the association of LDS with vascular complications, particularly pulmonary hypertension, in patients with SSc.Design, Setting, and ParticipantsThis retrospective cohort study used prospectively collected longitudinal data from a cohort of patients from the multidisciplinary rheumatology and dermatology clinic at a single tertiary care center from November 2004 to November 2022. Adult patients (aged ≥18 years at the time of cohort entry) with SSc were included.ExposureClinical diagnosis of LDS based on expert opinion or histopathologic findings.Main Outcomes and MeasuresThe main outcomes included prevalence of LDS, the association of LDS with the macrovascular complications, including pulmonary hypertension, digital gangrene and/or scleroderma renal crisis. Disease complications, including cardiac arrhythmias and heart failure, were compared among patients with and without LDS.ResultsAmong 567 patients with SSc (494 [87.1%] female; mean [SD] age, 53.4 [14.4] years), 25 (4.4%) had LDS and 542 (95.6%) did not have LDS. Skin ulceration occurred in 8 patients with LDS (32.0%). Patients with LDS had higher frequencies of cardiac arrhythmia (11 of 24 [45.8%] vs 145 of 539 [26.9%]), heart failure (7 [28.0%] vs 55 [10.1%]), and pulmonary hypertension (12 [48.0%] vs 137 of 541 [25.3%]) compared with patients without LDS. Frequency of scleroderma renal crisis and digital gangrene did not differ significantly between patients with and without LDS (0 vs 37 [6.8%] and 4 [16.0%] vs 69 of 538 [12.8%], respectively). Among patients with LDS, 9 (36.0%) were either discharged to hospice or died during follow-up compared with 115 patients without LDS (21.2%). Lipodermatosclerosis was associated with pulmonary hypertension (adjusted prevalence odds ratio, 3.10; 95% CI, 1.33-7.25).Conclusions and RelevanceIn this cohort study, LDS was a rare clinical manifestation in patients with SSc but was associated with pulmonary hypertension. Therefore, patients with LDS should be closely monitored and screened for pulmonary hypertension.
Open Access Publishing Metrics, Cost, and Impact in Health Professions Education Journals
Authors: Abdel-Razig Sawsan , Stadler Dora , Oyoun Alsoud Leen , Archuleta Sophia , Ibrahim Halah 
Published: October 2024

ImportancePublishing in health professions education (HPE) journals is an integral component of academic discourse and career progression. Research in this field is shifting to an open access (OA) publishing model.ObjectiveTo identify the characteristics and publishing models of HPE journals and explore potential associations between publication costs and journal metrics.Design, Setting, and ParticipantsThis cross-sectional study was conducted between September 20, 2023, and February 14, 2024, using the World Bank purchasing power parity (PPP) index to analyze relative costs of article processing charges (APCs). Data on journal characteristics, impact metrics, APCs, and waiver or discount were extracted from the National Library of Medicine, Scimago, Scopus, journal websites, and email correspondence with editorial staff of journals. All HPE journals indexed in PubMed, written in or translated into English, and with HPE as a core component of their mission were included in the analysis.Main Outcomes and MeasuresTwo-year impact factor, H-index, cite score, Scientific Journal Ranking, and APC.ResultsAmong the 51 journals included, 27 (53%) adopted OA-only and 24 (47%) adopted hybrid publishing models. The median (IQR) APC for all journals was $2820.00 ($928.00-$3300.00). Associations were observed between impact factor and APC (β coefficient, $386.84; 95% CI, $226.84-$546.84; P &amp;lt; .001) and between cite score and APC (β coefficient, $282.40; 95% CI, $148.12-$416.61; P &amp;lt; .001). Of 20 journal websites with information regarding fee waivers or discounts, 7 journals (35%) confirmed fee waiver or discount. The PPP index analysis of the top 39 countries publishing HPE research showed that the financial burden of meeting the median APC for publication was 1.94 to 10.26 times higher for authors from lower-income countries than for authors from the US.Conclusions and RelevanceResults of this cross-sectional study suggest that adoption by HPE journals of an OA publishing model was high but access to APC waivers or discounts was limited. These factors create barriers to equitable OA practices, necessitating concerted efforts, such as increasing transparency of publishing costs, implementing economic impact analysis, expanding waivers to eligible authors, and applying holistic impact factor scoring.
Emergency Care Use During Pregnancy and Severe Maternal Morbidity
Authors: Declercq Eugene R. , Liu Chia-Ling , Cabral Howard J. , Amutah-Onukagha Ndidiamaka , Diop Hafsatou , Mehta Pooja K. 
Published: October 2024

ImportancePregnant individuals who repeatedly use emergency care during pregnancy represent a population who could be disproportionately vulnerable to harm, including severe maternal morbidity (SMM).ObjectiveTo explore patterns of unscheduled care visits during pregnancy and ascertain its association with SMM at the time of birth.Design, Setting, and ParticipantsThis cohort study used data from a statewide database that linked hospital records to births and fetal deaths occurring between October 1, 2002, and March 31, 2020, in Massachusetts. Pregnant individuals experiencing births or fetal deaths during the study period were included. Data analysis was conducted from June 2022 to September 2024.ExposureThe exposure was 4 or more cases of emergency use, defined as either an emergency department visit or observational stay during pregnancy not resulting in hospital admission. Pregnancy episode was ascertained by subtracting the gestational age at birth from the date of birth.Main Outcomes and MeasuresThe outcome of interest was the odds ratio (OR) for SMM at the time of birth. The algorithm includes 20 conditions or procedures (excluding transfusion) identified through International Classification of Diseases, Ninth Revision and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision codes across the study period.ResultsA total of 774 092 pregnant individuals (mean [SD] age, 31.2 [5.8] years; 16.8% Hispanic, 9.3% non-Hispanic Asian or Pacific Islander, 9.5% non-Hispanic Black, 63.1% non-Hispanic White) with emergency care visits during the pregnancy were included; 31.3% of these individuals had at least 1 visit. Overall, 18.1% had 1 visit and 3.3% had 4 or more visits. Four or more unscheduled visits were common among those younger than age 25 years (8.7%), with Hispanic (5.7%) or non-Hispanic Black (4.9%) race and ethnicity, with public insurance (6.5%), or with a comorbidity (19.0%) or an opioid use–related hospitalization (26.8%) in the year prior to pregnancy. Of those with 4 or more unscheduled visits, 43.8% visited more than 1 hospital during pregnancy. In a multivariable analysis of the likelihood of SMM, those with 4 or more unscheduled visits had an adjusted OR of 1.46 (95% CI, 1.29-1.66) compared with those with 0 visits.Conclusions and RelevanceThis cohort study found that high emergency care use during pregnancy was associated with an increased risk for SMM. With a significant proportion of those with frequent unscheduled visits also using multiple hospitals, solutions that are community-based and integrated across health systems may be most beneficial.
Toward Equitable Interventions in Public Mental Health
Authors: Reininghaus Ulrich , Reinhold Annika S. , Priebe Stefan , Rauschenberg Christian , Fleck Leonie , Schick Anita , Schirmbeck Frederike , Myin-Germeys Inez , Morgan Craig , Hartmann Jessica A. 
Published: October 2024

ImportanceThe field of public mental health is evolving to tackle the profound impact of global challenges such as climate change, migration, and health crises. These issues accentuate health and social inequities, necessitating a focus on how to achieve interventions that are equitable and enhance mental health across all societal strata.ObservationsPopulation-based interventions can inadvertently exacerbate mental health inequities if they are primarily assessed by, and beneficial to, the most advantaged. Dimensional approaches such as the Hierarchical Taxonomy of Psychopathology offer a more nuanced understanding of mental health, capturing the whole spectrum of symptom severity in a culturally sensitive and less stigmatizing way. In addition, adopting intersectional, participatory, and settings-based approaches can help tailor interventions to the unique needs of marginalized groups.Conclusions and RelevanceIn moving toward more equitable interventions in public mental health, it is imperative to adopt an approach that integrates multiple frameworks to address the complexity of mental health inequities. At the core of this integrated approach is the recognition that mental health exists on a continuum. Intersectionality theory can help to identify the root (fundamental) causes of mental health while participatory and settings-based approaches ensure that interventions are relevant, culturally sensitive, and accessible to all. By adopting these approaches, interventions that are not only effective in “shifting the curve” toward better mental health, but are also equitable in their reach and impact, can be developed.
Entropy Increase in Electrolytes for Practical Anode‐Free Lithium Metal Batteries with High‐Loading Cathodes and Lean Electrolyte
Authors: Hu Fan , Chen Jing , Cao Hongshuai , Wang Haikuo , Guo Hao , Ouyang Xiaoping 
Published: October 2024

AbstractAn effective concept of using entropy increase to regulate the nanoscale solvation structure has been proposed to enhance the cycle performance of anode‐free lithium metal batteries (AFLMBs). It includes two mainstream types: entropy increase driven by multiple salts or solvents. However, most current research is based on low‐loading cathodes and mAh‐level battery systems. The relationship between the increase in entropy and practical battery with different high‐loading cathodes and Ah‐levels is seldom reported. In this paper, two mainstream methods of entropy increase are compared, and the relationship of their kinetics parameters, solid electrolyte interphase formation, and cycling performances are studied. It is found that the entropy increases driven by multiple‐solvents are more favorable to the pouch cell with high‐loading cathode and lean electrolytes. The coin cell consists of a copper current collector and a high‐loading cathode (10.5 mg cm−2) performs 40 cycles at discharge rates of 0.5 C, while the cell with a conventional ester electrolyte only last 10 cycles. A large‐capacity pouch cell (4 Ah), with a high‐loading cathode (7.6 mAh cm−2, single side) and lean electrolyte of 1.3 g Ah−1, achieves 500 Wh kg−1 and 20 cycles.
ALD of Metal Fluorides–Potential Applications and Current State
Authors: Atosuo Elisa , Mäntymäki Miia , Ritala Mikko 
Published: October 2024

AbstractMetal fluoride thin films are important materials in a multitude of applications. Currently, they are mostly used in optics, but their potential in energy harvesting and storage is recognized as well. Atomic layer deposition (ALD) is an advanced thin film deposition method that has an ever‐increasing role in microelectronics. The assets of ALD are its capability to produce uniform, stoichiometric, and pure films with precise thickness control even on top of complicated structures, such as high aspect ratio trenches. These characteristics can be beneficial in applications of metal fluoride thin films but so far ALD of metal fluorides has remained much less studied and used than ALD of metal oxides, nitrides, sulfides, and pure metals. This review aims to motivate research on ALD of metal fluorides by surveying potential applications for ALD metal fluoride thin films and coatings. The basics of luminescent applications, antireflection coatings, and lithium‐ion batteries will be discussed. Next, the fundamentals of ALD will be presented followed by a comprehensive summary of the metal fluoride ALD processes published so far.
Synergistic Reduction and Oxidation Resistant Interface Modifier for High‐Voltage and High‐Loading Solid‐State Lithium Batteries
Authors: Wu Jiaxin , You Zichang , Li Meng , Chen Huan , Feng Sheng , Wang Lingchen , Yuan Huihui , Jin Jun , Lu Yan , Wen Zhaoyin 
Published: October 2024

AbstractSolid‐state batteries (SSBs) with high‐voltage cathodes and Li‐anodes offer promising energy density and safety for next‐generation batteries. However, poor contact and electrochemical instability of solid electrolyte interfaces hinder their long‐term performance. Traditional rigid solidification interlayers possess restricted capability to address these issues. Herein, a composite buffer interlayer (CBI) with localized high‐concentration electrolytes (LHCEs) in a flexible polymer scaffold, tackling contact and stability problems and ensuring a perfect interface is developed. The extended electrochemical window provides it with synergistic antioxidation and antireduction capabilities, making it compatible with high‐voltage cathodes and Li anodes, while an in situ formed LiF‐Li3N rich inorganic interface ensures uniform lithium deposition and prevents dendrite formation. This CBI enables lithium symmetric cells to achieve a super high critical current density of 7.2 mA cm−2. Most impressively, coupled with a high‐voltage LiNi0.83Co0.12Mn0.05O2 cathode (NCM83), the full cell achieves 94.1% capacity retention after 125 cycles (coulombic efficiency >99.8%) at a mass loading of 14.6 mg cm−2 and a high voltage of 4.45 V. Additionally, a pouch cell with 17.2 mg cm−2 NCM83 achieves an initial discharge capacity of 3.82 mAh cm−2 an superior cycling stability (75 cycles, 89% capacity retention), showcasing the practical potential of LHCE‐CBI enabled SSBs.
From Local Farms to Supermarket Foods: The Story of the Homogenization of the Argentine Diet Told by the Isotope Ratios of Modern Teeth
Authors: Otero Felipe , Loupias Luciano Lautaro , Mancini Luis Henrique , Bahniuk R Anelize Manuela , Béguelin Marien , Valenzuela Luciano Oscar 
Published: October 2024

ABSTRACTObjectivesNutritional changes over the last century, driven by globalization, hypermarketization, and malnutrition, are global in scale. Large countries in the Global South might be resilient to dietary homogenization due to their natural diversity of regions and ecosystems, which might have prevented the adoption of supermarket diets. Argentina has a wide array of ecosystems and historically different subsistence diets dependent on regional characteristics. We analyzed the spatiotemporal variation of stable isotope values in Argentina using modern teeth to test for regional dietary patterns and its consistence over time.Materials and MethodsWe collected teeth from voluntary donors born between 1940 and 2010, from 72 locations across Argentina. A total of 119 teeth were analyzed for the markers δ
13Cdentine, δ
13Cenamel, δ
15N, and δ
34S. A reconstruction of isotopic niches was performed to estimate dietary patterns across different regions and time periods.ResultsThis study is the first to analyze changes in modern dietary patterns in Argentina using isotopic data measured in contemporary teeth. We showed latitudinal, longitudinal, and temporal differences in isotopic values, reflecting the variation in available resources within the country. Changes in the diet were observed over time, including declining δ
15N values, a reduction in δ
34S range, and a trend toward homogenization of δ
13Cenamel values. Conversely, δ
13Cdentine values remained constant over time, maintaining latitudinal patterns and regional differences across regions.DiscussionThis study increases our understanding of modern population dietary patterns both spatially and over the last 70 years. Our findings suggest that the Argentine population has shifted toward a supermarket diet in recent years.
Association of MIND diet with cognitive decline among Black and White older adults
Authors: Agarwal Puja , Barnes Lisa L. , Dhana Klodian , Liu Xiaoran , Zhang Yanyu , Beck Todd , Cornelis Marilyn C. , Tangney Christy , Rajan Kumar B. 
Published: October 2024

AbstractINTRODUCTIONWe examined the Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet's association with cognitive decline by race among older adults in the Chicago Health and Aging Project.METHODSFive thousand two hundred fifty‐nine participants (73.5 [± 6.0] years, 62% Black participants, 62% female) completed a food frequency questionnaire, and two or more cognitive assessments over 7.8 ± 4.6 years.RESULTSOverall, higher MIND diet was associated with slower cognitive decline (p for trend = 0.0025). The MIND score (range:0‐15) was different between Black and White older adults(6.97 vs. 7.12, p = 0.010). Compared to the lowest tertile, among White participants, the two highest tertiles (MIND score –7: β = 0.0121 [95% confidence interval [CI]: 0.0006, 0.0237]; MIND score –8.5: β = 0.0146 [95% CI: 0.0003, 0.0260]) and among Black participants, only the highest tertile (MIND score –8.5: β = 0.0088 [95% CI: 0.0003, 0.0172]) had association with cognitive decline. Vascular and lifestyle factors attenuated the association only for Black older adults.DISCUSSIONThe MIND diet was associated with slower cognitive decline in Black and White older adults, but this may vary with other lifestyle and vascular factors. Further research is warranted on race‐specific cultural diets considering other risk factors for cognitive decline.Highlights
The intake of Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet components varies by race.
The MIND diet may slow cognitive decline in both Black and White older adults.
This association may vary with other lifestyle and vascular risk factors.
Effects of nanosilica and nanocellulose on poly(butylene adipate‐co‐terephthalate) nanocomposites for food packaging applications
Authors: Sant'Anna Andrade Letícia , de Carvalho Silva Gabriela Cristina , de Oliveira Freitas Lione Viviane , da Silva Emerson Oliveira 
Published: October 2024

AbstractPolymeric materials are highlighted in the global market due to their low cost, excellent properties, and diversity of applications, such as food packaging, which in addition to protecting packaged foods also promotes control and conservation against contaminants. Thus, the objective of this research is to investigate the effects of adding silica nanoparticles and cellulose nanofibers, alone and together, on the properties of poly(butylene adipate‐co‐terephthalate), aiming for application in food packaging. For this purpose, PBAT and the nanofillers were initially mixed in a rheometer to produce masterbatches, and, then, to be processed by a single screw extruder to generate the nanocomposites. The nanocomposites are analyzed by scanning electron microscopy, x‐ray diffraction, thermogravimetric analysis, differential scanning calorimetry, nuclear magnetic resonance, tensile testing, water contact angle, and microbial permeability. In low concentrations, it is observed that the system tends to be less heterogeneous. Nanoparticles do not interfere with thermal stability and present a barrier to microorganisms. Interestingly, in the two conditions studied, polymers with cellulose nanofibers or silica nanoparticles have filtering capacity, being effective as physical barriers to the growth of microorganisms within 60 days. However, the effect on mechanical properties is small, being more pronounced with the use of cellulose nanofibers.
Community college student perceptions of digital anatomy models as a curricular resource
Authors: Baptiste Yvonne M. , Abramovich Samuel 
Published: October 2024

AbstractDigital model platforms and applications are common in anatomy education and continue to grow in number, which suggests that educators and students find use for these tools despite the lack of widely accepted best practices. Consequently, it is a challenge for educators to mindfully integrate digital models into curriculum. This short‐term, longitudinal study investigated the effects of integrating a monoscopic digital model as a teaching tool during lectures on reproductive and endocrine anatomy as an intervention in a community college human anatomy and physiology course. Student use and perceptions of digital models were analyzed for correlation with the nature of the course content and the intervention (n = 92). Academic content significantly affected self‐reported student use (p < 0.001) as well as student perceived usefulness of the model (p = 0.02). These findings support the conjecture that digital anatomy models may be better for achieving certain specific learning goals opposed to all learning goals. Integration of digital models as an instructional method did not consistently influence student behavior but it made a difference in participant ability to recognize this technology outside of the lecture. Overall, participants had a positive perception of digital models, although they were not perceived as more important than all other curricular resources. Inclusion of monoscopic digital models for teaching anatomy should be considered by educators since teaching with digital models can demonstrate strengths and weaknesses for students within the context the of learning objectives, assisting students to make more informed decisions about effective learning tools.
Structural Characteristics and DNA Groove Binding Abilities of Two Zinc‐Based Isoreticular MOFs
Authors: Chatterjee Taposi , Guha Priyam , Dutta Basudeb , Khan Samim , Siddiqui Masoom Raza , Wabaidur Saikh M. , Hedayetullah Mir Mohammad , Mafiz Alam Seikh 
Published: October 2024

AbstractIn this study, we have synthesized two zinc(II)‐based metal‐organic frameworks (MOFs) designated as [Zn(4‐nvp)(bdc)] ⋅ (MeOH) (1) and [Zn2(4‐nvp)2(bpdc)2] ⋅ (DMF) (2) [4‐nvp=4‐(1‐naphthylvinyl) pyridine, H2bdc=1,4‐benzendicarboxylic acid and H2bpdc=4,4′‐biphenyldicarboxylic acid]. Single‐crystal X‐ray diffraction (SCXRD) of both compounds unveiled an interesting paddle‐wheel [Zn2(O2C−C)4] secondary building block (SBB) composed of dinuclear Zn (II) centers and four dicarboxylate groups with a (4,4) square grid topology. These SBBs are interconnected giving rise to an infinite 2D layer architecture. Notably, the grid structure is composed of MeOH molecules in compound 1 and DMF molecules in compound 2, both of them arranged in a free lattice. In both compounds, 3D supramolecular architecture is ultimately formed through the stacking of 2D layers. Since the length of the bpdc ligand is higher than that of the bdc ligand, the solvent‐accessible void volume is comparatively higher for compound 2. To corroborate all non‐bonded interactions, Hirshfeld analysis was carried out for synthesized compounds. DNA binding application was extensively investigated through docking study. Results indicated that the synthesized compounds have strong affinities towards DNA via DNA groove binding. Henceforth, the synthesized compounds 1 and 2 would open the door for their potential applications as particular protein binders and bioactive substances.