bluuebunny/crossref_metadata_2025_split huggingface dataset:
Disputed Boundaries of the Self, the Group, and their Environment: What We Learn from Refugees about our Psychic Functioning1
Authors: Luci Monica 
Published: October 2024

AbstractOne of Jung’s most significant contributions concerns the mysterious, inexplicable and always out‐of‐reach nature of the self. In this paper, I will focus on the borders of the self and their nature, location and dynamics of maintenance and change in geographically, historically, and culturally situated subjects. Reflecting on the refugee experience, I intend to gain more insights into our psychic functioning and the dynamics of the self in relation to itself, the other and groups. The experiences of some refugees, marked bysignificant trauma and migration, shed light on how the boundaries of the self are frequently contested and perpetually negotiated with others, and how our subjectivity is shaped by ongoing dynamics of occupation, dispute and/or negotiation, conducted at various levels of our social and individual existence. My argument is that these processes occur at a specific site: the boundaries of the self, involving intrapsychic, interpersonal and group psychological dynamics, with reverberations in the socio‐political and cultural spheres, and reciprocal influences between all these levels. This paper aims to concentrate on the shifts in these boundaries, illustrated through clinical vignettes.
Comply or Explain: Do Firms Opportunistically Claim Trade Secrets in Mandatory Environmental Disclosure Programs?
Authors: JIANG YILE (ANSON) 
Published: October 2024

ABSTRACTThis paper studies whether firms opportunistically make proprietary claims in mandatory environmental disclosure programs with trade secret exemption rules. Examining the mandatory chemical disclosure program in the fracking industry, I find evidence of opportunistic withholding of information among operators that are less likely to have trade secrets. Specifically, I find that these operators claim fewer chemicals as trade secrets when the operating site is in close proximity to water quality monitors. This is only observed among publicly traded operators that face a higher cost of societal backlash when disclosing pollutant information. Further analyses suggest that these operators are concerned about external environmental monitoring, which deters them from opportunistic information withholding. Regarding public and private operators that are more likely to have trade secrets, I do not find strong evidence that their information withholding varies with the monitoring conditions.
Shopping around: Empirical analysis of borrower comparison shopping and mortgage prices
Authors: Jackson Kristoffer (Kip) , Senney Garrett T. 
Published: October 2024

AbstractUsing a novel approach to identifying mortgage price shopping on the universe of mortgages from 2018 to 2020, we find that relatively few borrowers shop, but those who do end saving roughly 11 basis points on average. We also find significant differences by race in the incidence and benefits of shopping. When borrowers do shop, a vast majority engage in simultaneous search. Shoppers show a swifter movement away from commercial banks toward fintechs. Shoppers tend to be more creditworthy, wealthier, live in more urban areas, and apply more often with nondepository lenders. Minority shoppers show less affinity to minority‐owned lenders than corresponding nonshoppers. We also provide evidence that shopping is likely significantly overreported in available survey data.
Hippocampal Nogo66‐NgR1 signaling activation restricts postsynaptic assembly in aged mice with postoperative neurocognitive disorders
Authors: Jia Min , Li Gui‐zhou , Chen Jiang , Tang Xiao‐hui , Zang Yan‐yu , Yang Guo‐lin , Shi Yun Stone , Ma Daqing , Ji Mu‐huo , Yang Jian‐jun 
Published: October 2024

AbstractPostoperative neurocognitive disorders (pNCD) are a common neurological complication, especially in elderly following anesthesia and surgery. Yet, the underlying mechanisms of pNCD remain elusive. This study aimed to investigate the molecular mechanisms that compromise synaptic metaplasticity in pNCD development with a focus on the involvement of Nogo‐66 receptor 1 (NgR1) in the pathogenesis of pNCD in aged mice. Aged mice subjected to anesthesia and laparotomy surgery exhibited anxiety‐like behavior and contextual fear memory impairment. Moreover, the procedure significantly increased NogoA and NgR1 expressions, particularly in the hippocampal CA1 and CA3 regions. This increase led to the depolymerization of F‐actin, attributed to the activation of the RhoA‐GTPase, resulting in a reduction of dendritic spines and changes in their morphology. Additionally, these changes hindered the efficient postsynaptic delivery of the subunit GluA1 and GluA2 of AMPA receptors (AMPARs), consequently diminishing excitatory neurotransmission in the hippocampus. Importantly, administering the competitive NgR1 antagonist peptide NEP1‐40 (Nogo‐A extracellular peptide residues 1–40 amino acids of Nogo‐66) and Fasudil (a Rho‐kinase inhibitor) effectively mitigated synaptic impairments and reversed neurocognitive deficits in aged mice following anesthesia and surgery. Our work indicates that high hippocampal Nogo66‐NgR1 signaling disrupts postsynaptic AMPA receptor surface delivery due to F‐actin depolymerization in the pathophysiology of pNCD.
The Joint Media Engagement Scale (JMES): An instrument for measuring shared media use with children aged 1 to 5 years old
Authors: Koch Felix‐Sebastian , Barr Rachel , Sundqvist Annette 
Published: October 2024

AbstractThe digital media landscape is rapidly shifting, and some children begin using digital media in infancy. As with book reading, young children need adult guidance to learn from digital media. Joint media engagement (JME) occurs when preschool children and their parents actively use digital media together. JME during early childhood is associated with increased learning from media. However, there are no validated scales of JME. In the present study, parents of 353 1‐to‐5‐year olds answered a series of questions about their media use and behaviours. Exploratory factor analysis yielded two scales, one for viewing video content together and one for playing digital games together. Convergent validity was established by comparison to the widely used Television Mediation Scale. Together, these findings establish the JME instrument as a valid and reliable tool for measuring joint media engagement during early childhood.
Course of immune thrombocytopenia according to the site of platelet destruction identified by indium‐111 platelet scintigraphy
Authors: Durand Pauline , Pottier Valérie , Debordeaux Frédéric , Mesguich Charles , Duffau Pierre , Lazaro Estibaliz , Viallard Jean‐François , Rivière Etienne 
Published: October 2024

SummaryIn primary immune thrombocytopenia (ITP), predictors of disease evolution and treatment response are needed. Data based on the site of platelet destruction are scarce. We performed a retrospective single‐centre study of adult patients with primary ITP undergoing at least one Indium‐111 platelet scintigraphy (IPS) between 2009 and 2018. Thirty‐three patients had isolated hepatic platelet destruction (H‐group), and 97 isolated splenic destruction (S‐group). Median age at diagnosis (p < 0.001), proportion of associated cardiovascular (p < 0.001), organ‐specific autoimmune diseases (p = 0.02), dependence on steroids (p = 0.003) and failure to rituximab (p = 0.01) were higher and relapse more frequent (p = 0.03) in H‐group compared to non‐splenectomized patients in S‐group. Splenectomy was only performed in patients from S‐group (as patients with hepatic sequestration are not splenectomized in our centre): 79% were in relapse‐free remission at the end of a median 3.4‐year post‐IPS follow‐up, 16% relapsed. In multivariate analyses, only a history of organ‐specific autoimmune or inflammatory disease was significantly associated with hepatic sequestration (OR = 4.3, 95% CI = 1.2–15, p = 0.02). Patients with isolated hepatic sequestration were older, had more cardiovascular events and organ‐specific autoimmune diseases, greater dependence on steroids, more relapses and a decreased response rate to rituximab suggesting an increased refractoriness to immunomodulatory therapies. Patients with isolated splenic sequestration responded well to splenectomy.
Ecosystem service assessment of coyote stories reveals tradeoffs from human–coyote interactions in rural Vermont, United States
Authors: Morse Joshua W. , Morse Cheryl E. , Gould Rachelle K. 
Published: October 2024

AbstractThe ecosystem system services framework has potential to help clarify wildlife management challenges at the single species scale, but existing methods struggle to capture the complex values and tradeoffs at play in human–wildlife interactions. We worked with community scientists to gather and use stories (n = 150) as a source of ecosystem services data about living alongside eastern coyotes (Canis latrans var) in rural Vermont, United States. Our a priori ecosystem service assessment showed that human–coyote interactions can have simultaneous positive and negative human well‐being impacts at both the sample scale and for individual interviewees. Our research identified emergent themes that lent insight into how interviewees justified different kinds of relationships with coyotes. We applied a tradeoffs lens to evaluate three policy options based on their potential to mitigate ecosystem disservices and maximize ecosystem services from human–coyote interactions. We found that ecosystem services assessment rooted in a dataset of stories revealed policy‐relevant understanding of value conflicts and alignments at the sample scale without overshadowing the nuances of individual interviewees' experiences.
Using key and critical biodiversity areas to identify gaps in the protected area network in the Limpopo Province, South Africa
Authors: Dalziel Alexandra , Evans Mary 
Published: October 2024

AbstractThe Kunming‐Montreal Global Biodiversity Framework (KMGBF) commits signatories to expand the global protection of land and sea by 30% in 2030. Additionally, in South Africa, a local target set in 2016 aims to conserve 16% of terrestrial areas using protected areas within a two‐decade time frame. Concurrently, it is crucial to recognize and prioritize sites where biodiversity must be protected immediately. This recognition has given rise to global Key Biodiversity Areas (KBAs) and South Africa's Critical Biodiversity Areas (CBAs). KBAs are sites of significance for the global persistence of biodiversity. In South Africa, CBAs delineate primarily or partially natural areas needing management. Despite their significance, an assessment of KBAs and CBAs in South Africa's Limpopo province, specifically the Vhembe District, is lacking. Employing GIS techniques, our evaluation focused on the coverage, size, and distribution of protected areas in the Vhembe District. Our analysis revealed that protected areas cover an impressive 38% of the Vhembe District. Critical Biodiversity Areas cover 9465 km2 (36%) of the region. Alarmingly, 70% (6809 km2) of these CBA sites lack protection. Additionally, KBAs cover 30% of the region, with 39% of sites covering approximately 3273 km2 and laying outside the protected area network, rendering them entirely unprotected. Sluggish protected areas establishment rates and a deficiency in the strategic targeting of significant sites have resulted in over 10,000 km2 of land warranting protection, particularly along the Soutpansberg Mountain Range. Moreover, South Africa's national target, established in 2016, which aims to protect a mere 16% of terrestrial areas by 2036, falls short of the global KMGBF target, reinforcing the urgency for an update in national policy and embracing other conservation methods. These findings suggest that, despite the commendable 38% protection of the district, setting a precedent for the rest of the country, there is a crucial need for municipalities, districts, and provinces to draw insights from the shortfalls of the Vhembe District.
Association of Donor Vascular Endothelial Growth Factor Gene Polymorphism With Acute Renal Allograft Rejection
Authors: Prasad Narayan , Yadav Brijesh , Bhatt Mansi , Chauhan Ranjeet , Agrawal Vinita 
Published: October 2024

AbstractBackgroundRecipient's VEGF‐A polymorphisms have been reported to be associated with the risk of acute allograft rejection. However, an association of the donor's VEGF‐A gene polymorphism with rejection remained unelucidated till now.MethodsIn this study, VEGF‐A gene SNPs at nine loci were analyzed in 160 kidney donors and recipients with rejection (rejectors, n = 80) and without rejection (non‐rejectors, n = 80). Blood VEGF‐A mRNA, plasma VEGF level, and intragraft VEGF expression were also analyzed by RT‐PCR, ELISA, and immunohistochemistry, respectively.ResultsOn comparing between the donor and rejectors, the polymorphic genotypes of VEGF –634 C>G [GG genotype, p < 0.0001; OR (95% CI) = 17.74 (5.16–60.96)]; VEGF –1154 G>A [AG genotype, p < 0.0001, OR (95% CI) = 16.07 (3.68–70.15)]; VEGF +936 C>T [CT genotype, p < 0.0001, OR (95% CI) = 178.64 (23.28–1370.9), and TT genotype, p < 0.0001; OR (95% CI) = 3149 (278.91–35 553)]; VEGF –1455 T>C [CC genotype, p value = 0.0464, OR (95% CI) = 3.13 (1.07–9.10)]; VEGF –2578 C>A [CA genotype, p = 0.0426, OR (95% CI) = 4.62 (1.03–20.59), and AA genotype, p value < 0.0001, OR (95% CI) = 21.89 (4.94–97.04)]; VEGF –2549 18 bp Insertion/Deletion [ID genotype, p value < 0.0001, OR (95% CI) = 27.27 (3.61–205.73) and DD genotype, p value < 0.0001, OR (95% CI) = 25.18 (3.30–191.89) were significantly associated with acute rejection risk. On comparing rejectors versus non‐rejectors, GA genotype of VEGF –1190 G>A and TC genotype of VEGF –1455 T>C were associated with the risk of rejection. On comparing donor VEGF between rejectors and non‐rejectors, CG genotype of VEGF –634 C>G, AG of VEGF –1154 G>A; GA of VEGF –1190 G>A were associated with rejection. The blood VEGF‐A mRNA and plasma VEGF levels were higher in the rejectors group compared to non‐rejectors.ConclusionsBesides the recipient's VEGF SNPS, the donor's VEGF SNPs are also associated with the risk of acute rejection and may be closely monitored in evaluation to determine the risk of rejection.
Long‐Term Stability of Marine Forests Facing Moderate Gradual Warming in a Remote Biodiversity Hotspot
Authors: Pessarrodona Albert , Wood Georgina , Grimaldi Camille M. , Goldberg Nisse , Kendrick Gary A. , Starko Samuel , Wernberg Thomas 
Published: October 2024

ABSTRACTAimOcean warming and marine heatwaves are rapidly reconfiguring the composition of seaweed forests—the world's largest coastal vegetated biome. Seaweed forest responses to climate change in remote locations, which constitute the majority of the forest biome, remain however poorly quantified. Here, we examine the temporal stability of the seaweed forests across a global seaweed biodiversity hotspot where several species are predicted to undergo severe range contractions in this century.LocationWestern south coast of Australia.MethodsSeaweed forest canopies were censused at 18 shallow (< 10 m) sheltered reefs between 1997 and 2006 and again between 2021 and 2024 (six sites per location). We also surveyed 24 sites to examine whether temporal changes differed over gradients of wave exposure and depth.ResultsSeaweed forest canopies across all locations showed surprisingly little change in biomass, cover, stand density and species composition over two decades, with strong spatial structuring across depth and exposure gradients persisting over time. The average thermal affinity of forest canopies (i.e., the community temperature index, CTI) did not track warming, suggesting that factors other than temperature (e.g., wave exposure and depth) are more important drivers of forest stand structure and/or that key thermal thresholds have not yet been crossed. Forests in the location with the most pronounced warming exhibited increased thermal bias over time (total bias of 0.8°C–2.2°C), indicating they were dominated by species with cooler affinities than their local temperatures.Main ConclusionsThe greater thermal bias in forests at the warmer edge of southern Australia suggests these will be more susceptible to future warming‐related compositional changes than forests in cooler locations. The relative stability we found contrasts with a current context of rapidly changing seaweed forests nationally and globally, highlighting the need to deepen our ecological understanding of the region so that future changes to its unique biodiversity and ecosystem services can be predicted and mitigated.
Use of continuous glucose monitoring and hybrid closed‐loop therapy in pregnancy
Authors: Benhalima Katrien , Yamamoto Jennifer M. 
Published: October 2024

AbstractContinuous glucose monitoring (CGM) has led to a paradigm shift in the management of pregnant women with type 1 diabetes (T1D), with improved glycaemic control, less hypoglycaemia and fewer pregnancy complications. Data on CGM use in pregnant women with type 2 diabetes (T2D) are limited. A large randomized controlled trial (RCT) on CGM use in people with T2D in pregnancy is ongoing. Small studies on CGM use in women with gestational diabetes (GDM) have suggested improved glycaemic control and better qualification when insulin is needed. However, none of these studies was powered to evaluate pregnancy outcomes. Several large RCTs are ongoing in women with GDM. In addition to CGM, other technologies, such as advanced hybrid closed‐loop (AHCL) systems have further improved glycaemic management in people with T1D. AHCL therapy adapts insulin delivery via a predictive algorithm integrated with CGM and an insulin pump. A large RCT with the AHCL CamAPS® FX demonstrated a 10% increase in time in range compared to standard insulin therapy in a pregnant population with T1D. Recently, an RCT of an AHCL system not approved for use in pregnancy (780G MiniMed) has also demonstrated additional benefits of AHCL therapy compared to standard insulin therapy, with improved time in range overnight, less hypoglycaemia and improved treatment satisfaction. More evidence is needed on the impact of AHCL therapy on maternal and neonatal outcomes and on which glycaemic targets with CGM should be used in pregnant women with T2D and GDM. We review the current evidence on the use of CGM and AHCL therapy in pregnancy.
Efficacy and Safety of Transthoracic Versus Transesophageal Echocardiography for Monitoring Closure of Atrial or Ventricular Septal Defects: A Systematic Review and Meta‐Analysis
Authors: Ben Lele , Zhang Yuanhao , Wang Yu , Xing Weizhen , Cai Jianping , Han Yu 
Published: October 2024

ABSTRACTPurposeFor the repair of atrial/ventricular septal defects (ASD/VSD), transthoracic echocardiography (TTE) is easy to perform, cost‐effective, and does not require general anesthesia and intubation. Still, TTE is not universally accepted. To compare efficacy and safety of TTE versus transesophageal echocardiography (TEE) to guide percutaneous ASD/VSD closure.MethodsPubMed, Embase, and the Cochrane library were searched for articles published from their inception to December 2023. The primary outcome was the procedural success rate. The secondary outcomes were residual shunt, late complications, procedure time, and fluoroscopy time. All meta‐analyses were performed using a random‐effects model.ResultsEight studies and 1295 patients were included. There were no significant differences between TTE and TEE regarding the procedural success rate (OR = 1.93, 95% CI: 0.90–4.13, p = 0.092; I2 = 52.2%, Pheterogeneity = 0.063) and residual shunt rate (OR = 0.81, 95% CI: 0.38–1.76, p = 0.600; I2 = 0%, Pheterogeneity = 0.518). Compared with TEE, TTE reduced the frequency of late complications (OR = 0.25, 95% CI: 0.14–0.43, p < 0.001; I2 = 13.8%, Pheterogeneity = 0.326), reduced the procedure time (WMD = −8.92, 95% CI: −12.08, −5.75, p < 0.001; I2 = 87.4%, Pheterogeneity < 0.001), and reduced the fluoroscopy time (WMD = −5.08, 95% CI: −9.59, −0.56, p = 0.028; I2 = 95.6%, Pheterogeneity < 0.001). The sensitivity analyses showed that the results of the meta‐analyses were robust.ConclusionCompared with TEE, TTE showed no differences regarding the rates of success and residual shunt, but there were lower rates of late complications and shorter procedure and fluoroscopy times.
Support Vector Machines With Uncertainty Option and Incremental Sampling for Kriging
Authors: Xiong Chen , Honeine Paul , Berar Maxime , van Exem Antonin 
Published: October 2024

ABSTRACTThis paper presents a novel approach to pollution assessment by investigating support vector machines (SVM) with an uncertainty option to overcome the limitations of traditional kriging. While kriging is a major tool for geostatistical modelling, allowing to estimate the distribution of contaminants in a region from a small set of samples, it does not allow to extract also the uncertainty map. An uncertainty map is of great interest, as it allows to identify regions of high uncertainty where one should sample in order to reduce high level of uncertainties. In this paper, we propose two variants of the SVM with an uncertainty option, each using a different hinge loss to improve the accuracy and efficiency. These losses allow to estimate different levels of contaminations, as well as uncertainty, such as the three levels: positive, uncertain and negative, namely for pollution estimation: high‐pollution, uncertain and low‐pollution. In addition to the exploration of SVM variants, we propose an innovative active sample selection strategy based on the uncertainty criterion. This strategy is designed to systematically reduce uncertainties in pollution assessment, thus providing adaptability to dynamic environmental changes. An incremental SVM with an uncertainty option is introduced to further optimise the sample selection process. Furthermore, the decision‐making process is refined through the introduction of a novel three‐hinge loss. The corresponding optimization problem and its resolution allow for a more nuanced contamination assessment with multiple levels of estimation, providing a valuable tool for characterising contamination levels with increased granularity. Extensive experiments on synthetic and real data validate the proposed methodology. Synthetic data simulations assess the quality of the approach, while real data from a two‐dimensional porosity measurement demonstrate practical applicability. This research contributes to the advancement of pollution assessment methodologies, providing an adaptable solution for environmental monitoring.