bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Voice’ and ‘Choice’ in Modern Working Practices: Problems With the Taylor Review
Authors: Bales Katie , Bogg Alan , Novitz Tonia 
Published: December 2017

Abstract
In July 2017, the Taylor Review on ‘Modern Working Practices’ was published. Led by Matthew Taylor, the Review aimed to consider the implications of new emerging business models for both worker rights and employer obligations. Its recommendations seem ill-informed, methodologically unsound and, ultimately, unlikely to address the widespread deprivation of workers’ rights within the ‘gig’ economy and contemporary workplace. We shape our critique of the Taylor approach by reference to the constructions of ‘choice’ used in the Review and the limited scope permitted for worker ‘voice’. In particular, we observe an evasion of international labour standards relevant to ‘decent work’ and a lack of attention to fundamental human rights. Identifying methodological flaws in the Report and focusing on three central areas of reform: employment status; zero-hours contracts (ZHCs); and workers’ voice and representation, this article critically analyses a number of the proposals put forward, concluding that many of the Taylor Review recommendations are not only problematic, but dangerous, with potentially serious deregulatory repercussions for UK workers if actioned upon and implemented by the current Government.
HD 156324: a tidally locked magnetic triple spectroscopic binary with a disrupted magnetosphere
Authors: Shultz M , Rivinius Th , Wade G A , Alecian E , Petit V ,   the BinaMIcS Collaboration
Published: December 2017

Abstract
HD 156324 is an SB3 (B2V/B5V/B5V) system in the Sco OB4 association. The He-strong primary possesses both a strong magnetic field and Hα emission believed to originate in its centrifugal magnetosphere. We analyse a large spectroscopic and high-resolution spectropolarimetric data set. The radial velocities (RVs) indicate that the system is composed of two subsystems, which we designate A and B. Period analysis of the RVs of the three components yields orbital periods Porb = 1.5806(1) d for the Aa and Ab components, and Porb = 6.67(2) d for the B component, a PGa star. Period analysis of the longitudinal magnetic field 〈Bz〉 and Hα equivalent widths, which should both be sensitive to the rotational period Prot of the magnetic Aa component, both yield ∼1.58 d. Since Porb = Prot Aa and Ab must be tidally locked. Consistent with this, the orbit is circularized, and the rotational and orbital inclinations are identical within uncertainty, as are the semimajor axis and the Kepler corotation radius. The star's Hα emission morphology differs markedly from both theoretical and observational expectations in that there is only one, rather than two, emission peaks. We propose that this unusual morphology may be a consequence of modification of the gravitocentrifugal potential by the presence of the close stellar companion. We also obtain upper limits on the magnetic dipole strength Bd for the Ab and B components, respectively, finding Bd < 2.6 and <0.7 kG.
A Review of Industry Funding in Randomized Controlled Trials Published in the Neurosurgical Literature—The Elephant in the Room
Authors: Khan Nickalus R , Saad Hassan , Oravec Chesney S , Rossi Nicholas , Nguyen Vincent , Venable Garrett T , Lillard Jock C , Patel Prayash , Taylor Douglas R , Vaughn Brandy N , Kondziolka Douglas , Barker Fred G , Michael L Madison , Klimo Paul 
Published: December 2017

Abstract

OBJECTIVE
To analyze the role of industry sponsorship of randomized controlled trials (RCTs) published exclusively in 3 major North American neurosurgical journals.

METHODS
Our primary objective was to determine whether an association exists between study conclusion(s) in favor of industry sponsored drugs, devices/implants, or surgical techniques and industry sponsorship. The secondary objective was to describe the quality/quantity of these neurosurgical RCTs.

RESULTS
A total of 110 RCTs were analyzed, the majority were published in the Journal of Neurosurgery (85%) and were international in origin (55%). The most common subspecialty was spine (n = 29) and drug study was the most common type (n = 49). Overall quality was good with median Jadad and Detsky scores of 4 (range, 1-5) and 18 (range, 8-21), respectively. There was a statistically significant difference in RCTs with industry funding (31/40, 78%) versus those without (9/70, 13%) that published a favorable conclusion of the new drug, device/implant, or surgical technique (odds ratio [OR], 23.35; P < .0001). Multiple binomial logistic regression analysis identified “number of authors” as mildly protective (OR, 0.79; 95% confidence interval, 0.69-0.91; P = .001) and “industry funding” strongly predictive (OR, 12.34; 95% confidence interval, 2.97-51.29; P = .001) of a positive trial.

CONCLUSION
Industry funding was associated with a much greater chance of positive findings in RCTs published in neurosurgical journals. Further efforts are needed to define the relationship between the authors and financial sponsors of neurosurgical research and explore the reasons for this finding.
Usefulness of Sealants for Dural Closure: Evaluation in an In Vitro Model
Authors: van Doormaal Tristan , Kinaci Ahmet , van Thoor Sander , Redegeld Saskia , Bergmann Wilhelmina , van der Zwan Albert 
Published: December 2017

Abstract

BACKGROUND
Cerebrospinal fluid (CSF) leakage occurs in 4% to 32% of cranial surgeries and is associated with significant patient burden and expense. The use of sealant as an adjunct to primary dural closure is assumed to help prevent CSF leakage.

OBJECTIVE
To examine the utility of different sealants for dural closure using an in Vitro model.

METHODS
We evaluated 9 commonly used dural sealants, including Tachosil (Takeda Inc, Osaka, Japan), Adherus (Hyperbranch Inc, Durham, North Carolina), Duraform (Codman, Raynham, Massachusetts), Tissudura (Baxter, Deerfield, Illinois), Hemopatch (Baxter), TissuePatchDural (Tissuemed, Leeds, United Kingdom), Tisseel (Baxter), Duragen Secure (Integra, Plainsboro, New Jersey), and Duraseal, (Integra). Sealants were tested in 2 novel in Vitro setups using fresh porcine dura: the first tested the acute burst pressure of a sealed 3-mm gap, while the second examined resistance to a pressure wave mimicking intracranial pressure for 72 h.

RESULTS
Adherus showed the highest mean burst pressure (87 ± 47 mmHg) followed by Tachosil (71 ± 16 mmHg) and Duraseal (51 ± 42 mmHg); these were the only 3 sealants showing burst pressures above normal physiological intracranial pressure. In the 72-h setup, only Adherus and Duraseal maintained appropriate sealing for the duration of the experiment. Tachosil released from the dura after 1.4 h (95% confidence interval, −1.8-4.7).

CONCLUSION
Given the high cost of sealants and the results of this study, we advocate a critical attitude toward sealant application as an adjunct to classic dural closure.
Narrative Ethics of Implication
Authors: Meretoja Hanna 
Published: December 2017

AbstractChapter 5 problematizes the prevalent way of conceptualizing the relationship between fiction and history in terms of the actual and the possible. It argues that both fictional and autobiographical narratives have potential to cultivate one’s sense of history as a sense of the possible, and it examines four different aspects of their contribution to historical imagination. The chapter analyzes how Günter Grass’s Hundejahre (1963, Dog Years) and his autobiography Beim Häuten der Zwiebel (2006, Peeling the Onion) explore the historical world of Nazi Germany as a space of possibilities, how they self-reflexively examine—against idealist and determinist conceptions—the way history consists in concrete actions and inactions, how they unearth the ways narrative interpretations of the past shape one’s orientation to the present, and how they address the duty to remember—and to engage with the conditions of possibility of atrocity—through a future-oriented narrative ethics of implication.
Lower extremity nontensioned traction pins: is it a benign procedure?
Authors: Shakir Irshad , Ganash Rajan , Watson J. Tracy 
Published: December 2017

Background:
To evaluate our institution’s infection rate with lower extremity traction pins and ascertain any risk factors. Additionally we sought to evaluate if the location of pin placement provided a higher risk of infection.

Methods:
This was a retrospective case-control study at a level 1 urban university trauma center. Five hundred and fifty six patients had 575 traction pins placed from February 2009 through December 2014. The intervention was bedside application of a centrally threaded 6-mm traction pin in the femur, tibia, or calcaneus. Radiographs were reviewed and zones were denoted. The diaphysis was bisected to determine anterior and posterior margins. The quadrant locations were as follows (1- proximal anterior, 2- proximal posterior, 3- distal anterior, and 4- distal posterior).

Results:
The total pins placed were 575 pins: 320 tibial, 236 femoral, and 19 calcaneal. There was an average of 9.6 mo of follow-up. There were five pin track infections (0.87%), all of which were treated successfully with oral antibiotics. There were two peroneal nerve injuries both which resolved by last follow-up. There was no septic arthritis of the knee. No correlations were noted between diabetes, body mass index, smoking, hypertension, and pin track infections or peroneal nerve injuries. There were 283 pins placed into zone 1, 166 in zone 2, 87 in zone 3, and 20 in zone 4. The 19 calcaneal pins were not categorized into quadrant systems. No correlation was noted between the bone in which the traction pin was placed and pin track infection or peroneal nerve injuries. Of the five pin track infections, all were placed in an eccentric posterior location. Four were in zone 2 and one in zone 4, which was statistically significant (P<0.05). No correlation was found between location of pins and peroneal nerve injury. The average time of pin placement to definitive surgery and pin removal was 2.83 days (0-28 days). There was no correlations between rates of infection and the amount of time in traction.

Conclusions:
This study revealed a low infection rate with 6-mm centrally threaded traction pins in our population. These larger, temporary lower extremity traction pins can be safely placed at the bedside and require no additional equipment for their use. Proximal and posteriorly placed pins in the tibia and femur have a correlation to pin track infections and thus should be avoided. These posteriorly placed pins tether more musculotendinous structures and, thus, are at risk for producing more immediate tissue necrosis with insertion and or use. Nontensioned anterior pins can be used with minimal risk of complication and are recommended.

Level of Evidence:
Prognostic level IV.
Acute Brachial Radiculoplexopathy and Giant Cell Arteritis
Authors: Duval Fanny , Lacoste Idoia , Galli Gaël , Chaumont Hugo , Solé Guilhem , Léger François , Damon-Perrière Nathalie , Rouanet Marie , Le Masson Gwendal , Mathis Stéphane 
Published: December 2017

Introduction:
Giant cell arteritis (GCA), a vasculitis involving large-sized and medium-sized vessels (which most commonly involves temporal arteries), is easily recognized in older patients presenting with headache, scalp tenderness, and raised inflammatory markers. Neurological complications (either central or peripheral) are classically described in GCA.

Case Report:
We report the case of an 85-year-old woman with bilateral acute brachial radiculoplexopathy, a rare neurological complication of GCA. She also presented right oculomotor palsy (with ptosis) and raised inflammatory markers, but she did not complain of the other classic cranial symptoms of the disease. We compare this case with 16 similar cases reported in the medical literature.

Conclusions:
In assessing a patient over 50 years of age with unexplained (unilateral or bilateral) brachial radiculoplexopathy (especially if C5-C6 nerve roots are affected) and elevated inflammatory markers, we would recommend specific enquiries with regard to the manifestations of GCA. The purpose is to reduce the risk of missing the wider spectrum of this condition and minimize the subsequent risk for disability of this treatable disease.
Core Set of Patient-reported Outcomes in Pancreatic Cancer (COPRAC)
Authors: van Rijssen Lennart B. , Gerritsen Arja , Henselmans Inge , Sprangers Mirjam A. , Jacobs Marc , Bassi Claudio , Busch Olivier R. , Fernández-Del Castillo Carlos , Fong Zhi Ven , He Jin , Jang Jin-Young , Javed Ammar A. , Kim Sun-Whe , Maggino Laura , Mitra Abhishek , Ostwal Vikas , Pellegrini Silvia , Shrikhande Shailesh V. , Wilmink Johanna W. , Wolfgang Christopher L. , van Laarhoven Hanneke W. , Besselink Marc G. 
Published: December 2017

Objective:
To establish an international core set of patient-reported outcomes (PROs) selected by both patients and healthcare providers (HCPs) from the United States (US), Europe, and Asia.

Summary Background Data:
PROs are increasingly recognized in pancreatic cancer studies. There is no consensus on which of the many available PROs are most important.

Methods:
A multicenter Delphi study among patients with pancreatic cancer (curative- and palliative-setting) and HCPs in 6 pancreatic centers in the US (Baltimore, Boston), Europe (Amsterdam, Verona), and Asia (Mumbai, Seoul) was performed. In round 1, participants rated the importance of 56 PROs on a 1 to 9 Likert scale. PROs rated as very important (scores 7–9) by the majority (≥80%) of curative- and/or palliative-patients as well as HCPs were included in the core set. PROs not fulfilling these criteria were presented again in round 2, together with feedback on individual and group ratings. Remaining PROs were ranked based on the importance ratings.

Results:
In total 731 patients and HCPs were invited, 501 completed round 1, and 420 completed both rounds. This included 204 patients in curative-setting, 74 patients in palliative-setting, and 142 HCPs. After 2 rounds, 8 PROs were included in the core set: general quality of life, general health, physical ability, ability to work/do usual activities, fear of recurrence, satisfaction with services/care organization, abdominal complaints, and relationship with partner/family.

Conclusions:
This international Delphi study among patients and HCPs established a core set of PROs in pancreatic cancer, which should facilitate the design of future pancreatic cancer trials and outcomes research.
The Effect of Foot Exercises on Wound Healing in Type 2 Diabetic Patients With a Foot Ulcer
Authors: Eraydin Şahizer , Avşar Gülçin 
Published: December 2017

PURPOSE:
The purpose of this study was to investigate the effect of foot exercises on wound healing in type 2 diabetic patients with a diabetic foot ulcer.

DESIGN:
Prospective, randomized controlled study.

SUBJECT AND SETTINGS:
Sixty-five patients from an outpatient clinic with grade 1 or 2 ulcers (Wagner classification) who met study criteria agreed to participate; 60 patients completed the study and were included in the final analysis. Subjects were followed up between February 2014 and June 2015.

METHODS:
Subjects were recruited by the researchers in the clinics where they received treatment. Subjects were randomly allocated to either the control or intervention group. Data were collected using investigator-developed forms: patient information form and the diabetic foot exercises log. Patients in the intervention group received standard wound care and performed daily foot exercises for 12 weeks; the control group received standard wound care but no exercises. The ulcers of the patients in both the intervention and control groups were examined and measured at the 4th, 8th, and 12th weeks. The groups were compared in terms of the ulcer size and depth. To analyze and compare the data, frequency distribution, mean (standard deviation), variance analysis, and the independent samples t test and the χ2 test were used.

RESULTS:
The mean ulcer areas were 12.63 (14.43), 6.91 (5.44), 4.30 (3.70), and 3.29 (3.80) cm2 (P < .05) in the study intervention group, and 24.67 (20.70), 24.75 (20.84), 20.33 (20.79), and 18.52 (21.49) cm2 in the control group in the 4th, 8th, and 12th weeks, respectively. Significant differences were found between diabetic foot ulcer sizes in the study intervention group in the 4th and 12th weeks compared to beginning baseline (P ≤ .05). However, only the 12th week was different from the beginning in the control group (P = .000). The mean depths of the ulcers were 0.56 (0.85), 0.42 (0.68), 0.36 (0.50), and 0.28 (0.38) cm in the study intervention group (P < .05) and 0.61 (0.84), 0.82 (1.07), 0.83 (1.21), and 0.80 (1.26) cm in the control group, respectively, at the baseline, and at the 4th, 8th, and 12th weeks, respectively (P = .000).

CONCLUSION:
The ulcer areas decreased significantly in the study intervention group compared to the control group during the 3 follow-up measurements. An important finding in this study was the DFU area decreased more in those who exercised more. Findings suggests foot exercises should be included in the treatment plan when managing patients with diabetic foot ulcers.
MLK1 and MLK2 Coordinate RGA and CCA1 Activity to Regulate Hypocotyl Elongation inArabidopsis thaliana
Authors: Zheng Han , Zhang Fei , Wang Shiliang , Su Yanhua , Ji Xiaoru , Jiang Pengfei , Chen Rihong , Hou Suiwen , Ding Yong 
Published: December 2017

AbstractGibberellins (GAs) modulate diverse developmental processes throughout the plant life cycle. However, the interaction between GAs and the circadian rhythm remains unclear. Here, we report that MUT9p-LIKE KINASE1 (MLK1) and MLK2 mediate the interaction between GAs and the circadian clock to regulate hypocotyl elongation in Arabidopsis thaliana. DELLA proteins function as master growth repressors that integrate phytohormone signaling and environmental pathways in plant development. MLK1 and MLK2 interact with the DELLA protein REPRESSOR OF ga1-3 (RGA). Loss of MLK1 and MLK2 function results in plants with short hypocotyls and hyposensitivity to GAs. MLK1/2 and RGA directly interact with CIRCADIAN CLOCK ASSOCIATED1 (CCA1), which targets the promoter of DWARF4 (DWF4) to regulate its roles in cell expansion. MLK1/2 antagonize the ability of RGA to bind CCA1, and these factors coordinately regulate the expression of DWF4. RGA suppressed the ability of CCA1 to activate expression from the DWF4 promoter, but MLK1/2 reversed this suppression. Genetically, MLK1/2 act in the same pathway as RGA and CCA1 in hypocotyl elongation. Together, our results provide insight into the mechanism by which MLK1 and MLK2 antagonize the function of RGA in hypocotyl elongation and suggest that MLK1/2 coordinately mediate the regulation of plant development by GAs and the circadian rhythm in Arabidopsis.
Enhancing graduate employability in product design
Authors: Watkins Matthew Alan , Higginson Martin , Clarke Philip Richard 
Published: December 2017

Purpose
The purpose of this paper is to present a case study to discuss approaches taken within a traditional undergraduate degree course to embed employability skills, encourage student uptake of sandwich placement and increase graduate prospects. A number of new initiatives are presented, including working with live industrial clients, formally preparing students for placement applications and the introduction of an externally facing student run design consortium. Alongside these new initiatives, details of the existing sandwich year provision are also considered and their effectiveness.

Design/methodology/approach
A case study-based action research approach presents changes to a specific undergraduate course, measuring the effectiveness over a four-year period using externally collected national Destination of Leavers in Higher Education (DLHE) data and internal student feedback to assess the long-term effects on employability.

Findings
The paper considers improvements in the graduate employability over the four year period covered, in particular, an increase in the graduate employability from 81 to 100 per cent and graduate prospects from 62.5 to 95.2 per cent for sandwich students. Data presented also considers additional student feedback correlating with an increase in their preparedness for employment.

Practical implications
The implications of undertaking the changes highlighted within this paper have been relatively straightforward, due to the small incremental nature of the changes and the opportunities available through the agencies within the university, and should be replicable at least in part at other HE institutions.

Originality/value
This paper considers the impact of employability initiatives undertaken on a single undergraduate course and how these have affected the employability of graduates over a four-year period, supported by student feedback both internally and externally through national feedback mechanisms. It is anticipated that this research would be beneficial for informing and guiding the development of employability on other undergraduate programmes.
Embedding research and enterprise into the curriculum
Authors: Brown Amy 
Published: December 2017

Purpose
The purpose of this paper is to review a year-long project entitled SaP@Parsons, which aims to bridge the gap between our current foundation degree curriculum and a revised curriculum where research and enterprise education were interwoven throughout, helping to better equip our graduates with the enhanced capacity to generate ideas and the skills to make them happen QAA (2012). The project used Student as Producer as a theoretical framework to embed research and enterprise into the curriculum. It was originally led by Professor Mike Neary at the University of Lincoln.

Design/methodology/approach
The paper reflects on the process of embedding research and enterprise education into the curriculum, including the experiences of the author and students.

Findings
It was found that reorientation of the curriculum is possible, without integrating enterprise specific learning aims into the programme to embed enterprise and research, can have a positive impact on both staff and student experience.

Practical implications
The paper provides a summary of strategies and examples of the effective use of Student as Producer as a framework for helping to embed research, enterprise and employability into a foundation degree curriculum and the resultant positive outcomes. The setting for this was HE provision within an FE college.

Originality/value
This paper highlights the innovative nature of the project in seeking to engage students in research and enterprise from level 4, rather than levels 6 or 7 within College-based Higher Education, through working with local social enterprises.