bluuebunny/crossref_metadata_2025_split huggingface dataset:
Speaking my patient's language: bilingual nurses’ perspective about provision of language concordant care to patients with limited English proficiency
Authors: Ali Parveen Azam , Johnson Stacy 
Published: September 2016

AbstractAimThe aim of this study was to explore bilingual nurses’ perspective about providing language concordant care to patients with limited English proficiency (LEP) and its impact on patients and nurses. Factors affecting the provision of language concordant care to patients LEP were also explored.BackgroundWith an increase in migration and mobility of people across the world, the likelihood of experiencing language barriers while providing and receiving care is high. Nurses are responsible for providing care to patients regardless of their culture, religion, ethnic background or language. Language barriers, however, are hurdles that hamper development of effective communication between nurses and patients. Eliminating language barriers is a crucial step in providing culturally competent and patient‐centred care.DesignQualitative descriptive study.MethodsDuring January‐August 2015, 59 nurses, working in acute hospitals in the UK, participated in 26 individual in‐depth interviews and three focus group discussions. The data were analysed using thematic analysis.FindingsFour themes: ‘when we speak the same language’; ‘when I speak my patient's language’; ‘what facilitates provision of language concordant care’ and ‘what hinders the provision of language concordant care’ were identified. Factors affecting nurses’ ability to provide language concordant care included individual factors (confidence; years of experience as a nurse; years of experience in the work setting; and relationship with colleagues), patients’ expectation, attitudes of other patients, colleagues and nurse managers, organizational culture and organizational policies.ConclusionBilingual nurses can play a very important role in the provision of language concordant for patients with LEP. Further research is needed to explore patient perspective.
MXRA5 is a TGF‐β1‐regulated human protein with anti‐inflammatory and anti‐fibrotic properties
Authors: Poveda Jonay , Sanz Ana B. , Fernandez‐Fernandez Beatriz , Carrasco Susana , Ruiz‐Ortega Marta , Cannata‐Ortiz Pablo , Ortiz Alberto , Sanchez‐Niño Maria D. 
Published: September 2016

AbstractCurrent therapy for chronic kidney disease (CKD) is unsatisfactory because of an insufficient understanding of its pathogenesis. Matrix remodelling‐associated protein 5 (MXRA5, adlican) is a human protein of unknown function with high kidney tissue expression, not present in rodents. Given the increased expression of MXRA5 in injured tissues, including the kidneys, we have suggested that MXRA5 may modulate kidney injury. MXRA5 immunoreactivity was observed in tubular cells in human renal biopsies and in urine from CKD patients. We then explored factors regulating MXRA5 expression and MXRA5 function in cultured human proximal tubular epithelial cells and explored MXRA5 expression in kidney cancer cells and kidney tissue. The fibrogenic cytokine transforming growth factor‐β1 (TGFβ1) up‐regulated MXRA5 mRNA and protein expression. TGFβ1‐induced MXRA5 up‐regulation was prevented by either interference with TGFβ1 activation of the TGFβ receptor 1 (TGFBR1, ALK5) or by the vitamin D receptor agonist paricalcitol. By contrast, the pro‐inflammatory cytokine TWEAK did not modulate MXRA5 expression. MXRA5 siRNA‐induced down‐regulation of constitutive MXRA5 expression resulted in higher TWEAK‐induced expression of chemokines. In addition, MXRA5 down‐regulation resulted in a magnified expression of genes encoding extracellular matrix proteins in response to TGFβ1. Furthermore, in clear cell renal cancer, von Hippel–Lindau (VHL) regulated MXRA5 expression. In conclusion, MXRA5 is a TGFβ1‐ and VHL‐regulated protein and, for the first time, we identify MXRA5 functions as an anti‐inflammatory and anti‐fibrotic molecule. This information may yield clues to design novel therapeutic strategies in diseases characterized by inflammation and fibrosis.
Fabrication, performance evaluation and optimization of Sal (shorea robusta) seed decorticator
Authors: Shashi Kumar C. , Pradhan Rama Chandra , Mishra Sabyasachi 
Published: September 2016

AbstractSal (Shorea robusta) seed is a nontimber forest product, mainly processed for its oil. This oil is used in various food and nonfood industries. Prior to extraction of oil, sal seeds are manually broken to obtain sal kernel. This traditional manual de‐shelling process is very tedious, time consuming and unhygienic. Hence, in this research, a sal seed decorticator was designed, fabricated and its performance was evaluated. The performance parameters of the machine were tested with varying moisture content from 10.49% to 21.95% (d.b) and different concave clearance varying from 10 mm to 19 mm. The decorticating efficiency, machine efficiency, and kernel percentage were found to have a maximum value of 99.15
0.04%, 93.62
0.87%, and 62.71
1.73%, respectively at 13.63% (d.b) moisture content and 13 mm concave clearance. Results were fitted in response surface methodology to optimize the parameters and to find the level of significance between the independent and dependent variables.Practical applicationsA sal seed decorticator was developed based on physical and mechanical properties of sal seed. The developed machine is designed to run by manpower (manually operated) which can be suitable for hilly and forest region. This decorticator can be used to decorticate sal seeds to get sal kernels. At a seed moisture content of 13.63% (d.b.), the decorticator yields 62.71% of kernels (machine efficiency of 93.62%). These kernels are processed for extraction of oil. This machine is very useful for rural people, farmers and small‐scale industries for post‐harvest processing of sal seeds.
Quality of meta‐analyses in major leading gastroenterology and hepatology journals: A systematic review
Authors: Liu Pengfei , Qiu Yuanyu , Qian Yuting , Chen Xiao , Wang Yiran , Cui Jin , Zhai Xiao 
Published: September 2016

AbstractBackground and AimTo appraise the current reporting methodological quality of meta‐analyses in five leading gastroenterology and hepatology journals, and to identify the variables associated with the reporting quality.MethodsWe systematically searched the literature of meta‐analyses in Gastroenterology, Gut, Hepatology, Journal of Hepatology (J HEPATOL) and American Journal of Gastroenterology (AM J GASTROENTEROL) from 2006 to 2008 and from 2012 to 2014. Characteristics were extracted based on the PRISMA statement and the AMSTAR tool. Country, number of patients, funding source were also revealed and descriptively reported.ResultsA total of 127 meta‐analyses were enrolled in this study and were compared among journals, study years, and other characters. Compliances with the PRISMA statement and the AMSTAR checklist were 20.8 ± 4.2 out of a maximum of 27 and 7.6 ± 2.4 out of a maximum of 11, respectively. Some domains were poorly reported including describing a protocol and/or registration (item 5, 0.0%), describing methods, and giving results of additional analyses (item 16, 45.7% and item 23, 48.0%) for PRISMA and duplicating study selection and data extraction (item 2, 53.5%), and providing a list of included and excluded studies (item 5, 14.2%) for AMSTAR. Publication in recent years showed a significantly better methodological quality than those published in previous years.ConclusionsThis study shows that methodological reporting quality of MAs in the major gastroenterology and hepatology journals has improved in recent years after the publication of the developed PRISMA statement, and it can be further improved.
Can a Healthy Lifestyle Compress the Disabled Period in Older Adults?
Authors: Jacob Mini E. , Yee Laura M. , Diehr Paula H. , Arnold Alice M. , Thielke Stephen M. , Chaves Paulo H. M. , Gobbo Liana Del , Hirsch Calvin , Siscovick David , Newman Anne B. 
Published: September 2016

ObjectivesTo determine whether lifestyle factors, measured late in life, could compress the disabled period toward the end of life.DesignCommunity‐based cohort study of older adults followed from 1989 to 2015.SettingFour U.S. communities.ParticipantsCommunity‐living men and women aged 65 and older (N = 5,248, mean age 72.7 ± 5.5, 57% female, 15.2% minority) who were not wheelchair dependent and were able to give informed consent at baseline.MeasurementsMultiple lifestyle factors, including smoking, alcohol consumption, physical activity, diet, body mass index (BMI), social networks, and social support, were measured at baseline. Activities of daily living (ADLs) were assessed at baseline and throughout follow‐up. Years of life (YoL) was defined as years until death. Years of able life (YAL) was defined as years without any ADL difficulty. YAL/YoL%, the proportion of life lived able, was used to indicate the relative compression or expansion of the disabled period.ResultsThe average duration of disabled years was 4.5 (out of 15.4 mean YoL) for women and 2.9 (out of 12.4 mean YoL) for men. In a multivariable model, obesity was associated with 7.3 percentage points (95% confidence interval (CI) = 5.4–9.2) lower YAL/YoL% than normal weight. Scores in the lowest quintile of the Alternate Healthy Eating Index were associated with a 3.7% (95% CI = 1.6–5.9) lower YAL/YoL% than scores in the highest quintile. Every 25 blocks walked in a week was associated with 0.5 percentage points (95% CI = 0.3–0.8) higher YAL/YoL%.ConclusionThe effects of healthy lifestyle factors on the proportion of future life lived free of disability indicate that the disabled period can be compressed, given the right combination of these factors.
Challenges for Nurses Caring for Individuals with Peripherally Inserted Central Catheters in Skilled Nursing Facilities
Authors: Harrod Molly , Montoya Ana , Mody Lona , McGuirk Helen , Winter Suzanne , Chopra Vineet 
Published: September 2016

ObjectivesTo understand the perceived preparedness of frontline nurses (registered nurses (RNs), licensed practical nurses (LPNs)), unit nurse managers, and skilled nursing facility (SNF) administrators in providing care for residents with peripherally inserted central catheters (PICCs) in SNFs.DesignExploratory, qualitative pilot study.SettingTwo community based SNFs.ParticipantsResidents with PICCs, frontline nurses (RNs, LPNs), unit nurse managers, and SNF administrators.MethodsOver 36 weeks, 56 residents with PICCs and their nurses were observed and informally interviewed, focusing on PICC care practices and documentation. In addition, baseline PICC data were collected on placement indication (e.g., antimicrobial administration), placement setting (hospital vs SNF), and dwell time. Focus groups were then conducted with frontline nurses and unit nurse managers, and semistructured interviews were conducted with SNF administrators to evaluate perceived preparedness for PICC care. Data were analyzed using a descriptive analysis approach.ResultsVariations in documentation were observed during weekly informal interviews and observations. Differences were noted between resident self‐reported PICC concerns (quality of life) and those described by frontline nurses. Deficiencies in communication between hospitals and SNFs with respect to device care, date of last dressing change, and PICC removal time were also noted. During focus group sessions, perceived inadequacy of information at the time of care transitions, limited availability of resources to care for PICCs, and gaps in training and education were highlighted as barriers to improving practice and safety.ConclusionPractices for PICC care in SNFs can be improved. Multimodal strategies that enhance staff education, improve information exchange during care transitions, and increase resource availability in SNFs appear necessary to enhance PICC care and safety.
Green tea extract and catechol‐O‐methyltransferase genotype modify the post‐prandial serum insulin response in a randomised trial of overweight and obese post‐menopausal women
Authors: Dostal A. M. , Arikawa A. , Espejo L. , Bedell S. , Kurzer M. S. , Stendell‐Hollis N. R. 
Published: September 2016

AbstractBackgroundGreen tea extract (GTE) may be involved in a favourable post‐prandial response to high‐carbohydrate meals. The catechol‐O‐methyltransferase (COMT) genotype may modify these effects. We examined the acute effects of GTE supplementation on the post‐prandial response to a high‐carbohydrate meal by assessing appetite‐associated hormones and glucose homeostasis marker concentrations in women who consumed 843 mg of (−)‐epigallocatechin‐3‐gallate (EGCG) or placebo capsules for 11–12 months.MethodsSixty Caucasian post‐menopausal women (body mass index ≥ 25.0 kg m–2) were included in a randomised, double‐blind feeding study. GTE was consumed with a breakfast meal [2784.0 kJ (665.4 kcal); 67.2% carbohydrate]. Blood samples were drawn pre‐meal, post‐meal, and every 30 min for 4 h. Participants completed six satiety questionnaires.ResultsPlasma leptin, ghrelin and adiponectin did not differ between GTE and placebo at any time point; COMT genotype did not modify these results. Participants randomised to GTE with the high‐activity form of COMT (GTE‐high COMT) had higher insulin concentrations at time 0, 0.5 and 1.0 h post‐meal compared to all COMT groups randomised to placebo. Insulin remained higher in the GTE‐high COMT group at 1.5, 2.0 and 2.5 h compared to Placebo‐low COMT (P < 0.02). GTE‐high COMT had higher insulin concentrations at times 0, 0.5, 1.0, 1.5 and 2.0 h compared to the GTE‐low COMT (P ≤ 0.04). Area under the curve measurements of satiety did not differ between GTE and placebo.ConclusionsGTE supplementation and COMT genotype did not alter acute post‐prandial responses of leptin, ghrelin, adiponectin or satiety, although it may be involved in post‐meal insulinaemic response of overweight and obese post‐menopausal women.
Adding glucose to food and solutions to enhance fructose absorption is not effective in preventing fructose‐induced functional gastrointestinal symptoms: randomised controlled trials in patients with fructose malabsorption
Authors: Tuck C. J. , Ross L. A. , Gibson P. R. , Barrett J. S. , Muir J. G. 
Published: September 2016

AbstractBackgroundIn healthy individuals, the absorption of fructose in excess of glucose in solution is enhanced by the addition of glucose. The present study aimed to assess the effects of glucose addition to fructose or fructans on absorption patterns and genesis of gastrointestinal symptoms in patients with functional bowel disorders.MethodsRandomised, blinded, cross‐over studies were performed in healthy subjects and functional bowel disorder patients with fructose malabsorption. The area‐under‐the‐curve (AUC) was determined for breath hydrogen and symptom responses to: (i) six sugar solutions (fructose in solution) (glucose; sucrose; fructose; fructose + glucose; fructan; fructan + glucose) and (ii) whole foods (fructose in foods) containing fructose in excess of glucose given with and without additional glucose. Intake of fermentable short chain carbohydrates (FODMAPs; fermentable, oligo‐, di‐, monosaccharides and polyols) was controlled.ResultsFor the fructose in solution study, in 26 patients with functional bowel disorders, breath hydrogen was reduced after glucose was added to fructose compared to fructose alone [mean (SD) AUC 92 (107) versus 859 (980) ppm 4 h–1, respectively; P = 0.034). Glucose had no effect on breath hydrogen response to fructans (P = 1.000). The six healthy controls showed breath hydrogen patterns similar to those with functional bowel disorders. No differences in symptoms were experienced with the addition of glucose, except more nausea when glucose was added to fructose (P = 0.049). In the fructose in foods study, glucose addition to whole foods containing fructose in excess of glucose in nine patients with functional bowel disorders and nine healthy controls had no significant effect on breath hydrogen production or symptom response.ConclusionsThe absence of a favourable response on symptoms does not support the concomitant intake of glucose with foods high in either fructose or fructans in patients with functional bowel disorders.
Lived experience of blood glucose self‐monitoring among pregnant women with gestational diabetes mellitus: a phenomenological research
Authors: Youngwanichsetha Sununta , Phumdoung Sasitorn 
Published: September 2016

Aims and objectivesTo explore and describe lived experience of blood glucose self‐monitoring among pregnant Thai women with gestational diabetes mellitus.BackgroundSelf‐monitoring of blood glucose is an essential practice among pregnant women with diabetes to prevent complications in pregnancy and the newborn infant.DesignPhenomenological research was employed to understand lived experiences in glycemic control.MethodsThirty participants were approached and interviewed using a semistructured interview guides. Qualitative data were analysed following Colaizzi's method.ResultsThe findings revealed three themes: being worried about diabetes and blood testing, trying to control it and being patient for the child. Their worry comprised three dimensions: (1) wondering about the impacts of diabetes on the child, (2) concern about maternal health and (3) being worried about doing blood test. Trying to control diabetes was composed of three dimensions: (1) learning to test blood glucose, (2) being afraid of elevated blood sugar and (3) being aware of what to eat. Being patient for the child was composed of three dimensions: (1) overcoming food desires, (2) tolerating the fingerprick pain and (3) satisfaction with the outcomes.ConclusionsWomen with gestational diabetes experienced being worried and afraid regarding blood glucose self‐monitoring; however, they could overcome and tolerate this with some difficulties.Relevance to clinical practiceThese findings can be used to guide nursing practice in assessment of perception and response towards blood glucose self‐monitoring in order to improve achievement of a good glycaemic control among pregnant women with gestational diabetes mellitus.
Cultural and religious beliefs and values, and their impact on preferences for end‐of‐life care among four ethnic groups of community‐dwelling older persons
Authors: Ohr Seok , Jeong Sarah , Saul Peter 
Published: September 2016

Aims and objectivesTo explore specific cultural and religious beliefs and values concerning death and dying, truth telling, and advance care planning, and the preferences for end‐of‐life care among older persons from culturally and linguistically diverse backgrounds.BackgroundWhilst literature indicates that culture impacts on end‐of‐life decision‐making significantly, there is limited evidence on the topic.DesignA cross‐sectional survey.MethodsA total of 171 community older persons who make regular visits to 17 day care centres expressed in a questionnaire their; (1) beliefs about death and dying, truth telling, and advance care planning, and (2) preferences for end‐of‐life care.ResultsMore than 92% of respondents believed that dying is a normal part of life, and more than 70% felt comfortable talking about death. Whilst respondents accepted dying as a normal part of life, 64% of Eastern Europeans and 53% of Asia/Pacific groups believed that death should be avoided at all costs. People from the Asia/Pacific group reported the most consensual view against all of the life‐prolonging measures.ConclusionCultural and religious beliefs and values may have an impact on preferences for treatment at end‐of‐life. The study offers nurses empirical data to help shape conversations about end‐of‐life care, and thus to enhance their commitment to help people ‘die well’.Relevance to clinical practiceInformation acquisition to extend understanding of each individual before proceeding with documentation of advance care planning is essential and should include retrieval of individuals’ cultural and religious beliefs and values, and preferences for care. An institutional system and/or protocol that promote conversations about these among nurses and other healthcare professionals are warranted.
Job Satisfaction of People With Intellectual Disabilities in Integrated and Sheltered Employment: An Exploration of the Literature
Authors: Akkerman Alma , Janssen Cees G. C. , Kef Sabina , Meininger Herman P. 
Published: September 2016

AbstractPaying attention to job satisfaction of people with intellectual disabilities, in either integrated or sheltered employment, is important, to increase individual as well as organizational functioning and well‐being. Nevertheless, little is known about job satisfaction of employees with intellectual disabilities and the factors increasing or hindering this. The aim of this study was to explore existing research evidence regarding job satisfaction of people with intellectual disabilities in integrated and sheltered employment settings, and its associated factors. A systematic and comprehensive literature search revealed 13 relevant studies that were examined. Results indicated that people with intellectual disabilities in integrated employment and sheltered employment generally report satisfaction with their jobs. Satisfaction levels appear to be higher in integrated employment. Furthermore it was found that characteristics of the employee and of the employment setting were associated with job satisfaction, as well as social relations, support, and the fit between the employees’ needs and the work environment. Advancements can be made with respect to policy and practice of employment of people with intellectual disabilities. To improve their job satisfaction we suggest an integrative approach, taking into account that job satisfaction is an interplay between personal, situational, and social‐cognitive characteristics. This is reflected in current theoretical frameworks in general job satisfaction literature. Future research on job satisfaction of people with intellectual disabilities could profit from developments in general job satisfaction literature and in addition take account of factors particularly relevant to people with intellectual disabilities, the possible impact of comparison processes, and the development of sound measurement methods. Finally, we advocate for greater insight and involvement of people with intellectual disabilities in career related matters, to enhance their self‐determination and motivation and increase satisfaction.
Oral and dental diseases in a population of domestic ferrets (Mustela putorius furo)
Authors: Nemec A. , Zadravec M. , Račnik J. 
Published: September 2016

ObjectiveDomestic ferrets have been used for many purposes, but recently their popularity as companion animals has increased greatly. However, data on their oral and dental diseases are rare. The objective of this study was therefore to describe oral and dental diseases in a population of client‐owned domestic ferrets.MethodsIn this cross‐sectional clinical study, detailed oral and dental examination and full‐mouth dental radiographs were performed in 57 client‐owned ferrets.ResultsVariations in occlusion and number of roots per tooth were noted in comparison with previously published literature on ferrets. Periodontal disease, attrition/abrasion and dental fractures, especially of the canine teeth, were commonly observed. Periapical disease associated with dental fractures, malocclusion, tooth resorption and neoplasia was uncommon.Conclusion and Clinical RelevanceThis study indicates that thorough oral and dental examination supported by dental radiography under general anaesthesia should be performed in domestic ferrets as a part of regular veterinary care.