bluuebunny/crossref_metadata_2025_split huggingface dataset:
Testing the Potential Clastogenic/Cytotoxic Effects of Pesticide CALYPSO 480 SC
Authors: Ficová I. , Galdíková M. 
Published: October 2017

Abstract
The detection of chromosomal damage serves as a tool for the verification of the genotoxic effects of chemical substances in vitro. We used conventional cytogenetic analysis in order to test for the potential genotoxic action of the insecticide thiacloprid (the active ingredient in commercial preparation CALYPSO 480 SC). The test cultures of bovine lymphocytes obtained from the peripheral blood were incubated with the insecticide in concentrations of: 30, 120, 240 and 480 μg.ml−1 for 24 and 48 hours. After 24 hours of incubation, we observed that the increasing concentrations resulted in a significant (P < 0.05; P < 0.01) increase in the frequency of DNA damage. Our experiments showed the presence of aberrations of a non-stable type (chromatid and chromosome breakage). The conventional chromosome analysis was supplemented with fluorescence in situ hybridization for the detection of numeric and stable structural aberrations. Whole chromosome probes for bovine chromosomes 1, 5 and 7 (BTA 1, BTA 5 and BTA 7) were used in the experiments.
Determination of Antibiotic Residues in Milk by Microbial Inhibitory Tests
Authors: Juščáková D. , Kožárová I. 
Published: October 2017

Abstract
Undesirable substances enter the organism of animals mostly via feed, water or veterinary medicines and their residues pass subsequently into the products of animal origin. In dairy cows, sheep and goats these residues are eliminated particularly in milk. Milk intended for human consumption must comply with safety criteria also with respect to residues of antibiotics. The aim of this study was to determine the presence or absence of antibiotic residues in the milk using the tests Milchtest and Premi®Test. While the Milchtest was developed for the determination of antibiotic residues in cow, sheep and goat milk, the Premi®Test is intended for the determination of antibiotic residues in meat juice, liver, kidneys, fish, eggs and in the urine of animals treated with antibiotics. As examined matrices, we used 45 samples of raw cow’s milk collected at 3 agricultural farms and 10 samples of milk offered to consumers at grocery stores. When using the Milchtest, 8 samples tested positive and 10 provided dubious results while testing with the Premi®Test showed that only 6 samples were positive for antibiotics. Comparison of the results confirmed a higher detection sensitivity of Milchtest reflected in higher numbers of positive samples and the detection of dubious results in samples of raw cow’s milk. However, it should be noted that even the Premi®Test, although not intended preferably for the determination of antibiotics in milk, can be used, if needed, for the preliminary screening of antibiotic residues in such a matrix.
Andersen’s leaf-nosed bat (Hipposideros pomona) is still living in the Chittagong Hill Tracts, Bangladesh
Authors: Saha Anik , Feeroz Mohammed Mostafa , Hasan Md. Kamrul 
Published: October 2017

Abstract
We report the recent record of Andersen’s leaf-nosed bat, Hipposideros pomona (Andersen 1918) from a narrow cave in the south-east corner of the Chittagong Hill Tracts (CHT), Bangladesh. The identification was based on morphometric analysis along with dentition structure. This recent finding speaks to the existence of H. pomona in Bangladesh and extends the range of this species over South Asia.
Bearing Estimation Using Double Frequency Reassignment for a Linear Passive Array
Authors: Czarnecki Krzysztof , Leśniak Wojciech 
Published: October 2017

Abstract
The paper demonstrates the use of frequency reassignment for bearing estimation. For this task, signals derived from a linear equispaced passive array are used. The presented method makes use of Fourier transformation based spatial spectrum estimation. It is further developed through the application of two-dimensional reassignment, which leads to obtaining highly concentrated energy distributions in the joint frequency-angle domain and sharp graphical imaging. The introduced method can be used for analysing, a priori, unknown signals of broadband, nonstationary, and/or multicomponent type. For such signals, the direction of arrival is obtained based upon the marginal energy distribution in the angle domain, through searching for arguments of its maxima. In the paper, bearing estimation of three popular types of sonar pulses, including linear and hyperbolic frequency modulated pulses, as well as no frequency modulation at all, is considered. The results of numerical experiments performed in the presence of additive white Gaussian noise are presented and compared to conventional digital sum-delay beamforming performed in the time domain. The root-mean-square error and the peak-to-average power ratio, also known as the crest factor, are introduced in order to estimate, respectively, the accuracy of the methods and the sharpness of the obtained energy distributions in the angle domain.
Influence of Water and Mineral Oil on the Leaks in Satellite Motor Commutation Unit Clearances
Authors: Śliwiński Paweł 
Published: October 2017

Abstract
The article describes the flow rates of mineral oil and water flowing, as working media, through the commutation unit of a hydraulic satellite motor. It is demonstrated that geometrical dimensions of commutation unit clearances change as a function of the machine shaft rotation angle. Methods for measuring the rate of this flow and the pressure in the working chamber are presented. The results of pressure measurements in the working chamber during the transition from the filling cycle to the emptying cycle are included. The pressure in the motor’s working chamber changes linearly as a function of the shaft rotation angle, which has a significant effect on the leakage in the commutation unit clearances. The paper presents new mathematical formulas in the form: Q=f(Δpγ) to calculate the flow rate of water and mineral oil in the commutation unit clearances. The γ factor is described as a function of fluid viscosity and clearance length (the motor shaft rotation angle). The coefficients used in these formulas were determined based on the results of laboratory tests of a motor supplied with water and mineral oil.
Transcatheter Vs. Surgical Closure of Atrial Septal Defects in Adults
Authors: Rudzītis Ainārs , Šablinskis Kristaps , Luriņa Baiba , Cgojeva-Sproģe Irina , Grāve Aļona , Dombrovskis Andis , Stradiņš Pēteris , Ērglis Andrejs 
Published: October 2017

Abstract
Percutaneous transcatheter device closure of secundum atrial septal defects (ASD) has now largely replaced surgical closure in most centres. The aim of this study was to compare results of transcatheter and surgical ASD closure in adults in Latvia during the years 2002–2014 and to analyse long-term outcomes of transcatheter closure. We analysed data from 334 patients with secundum ASD who underwent ASD closure in Pauls Stradiņš Clinical University Hospital. Patients were included into device or surgical closure groups. In the device group, three follow-ups were made 1, 6, and 12 months after the procedure. No follow-up data were available for surgical arm patients beyond their hospitalisation period. The mean age of patients was 45.3 ± 19.9 years for the device group and 40.0 ± 16.9 years for the surgical group (p = 0.023). The mean secundum ASD size in the device and surgical groups was 14.2 ± 5.6 mm and 28.7 ± 10.0 mm, respectively (p < 0.001). No differences were observed regarding procedure success rates: 99.2% in the device group and 100% in the surgical group (p = 0.451). Periprocedural complications generally were more common in the surgical closure group. The study results show a successful introduction of the percutaneous ASD closure method in Latvia with good early and late outcomes and without significant differences in procedure success rate compared to surgical closure.
THz imaging for recycling of black plastics
Authors: Küter Andries , Reible Stefan , Geibig Thomas , Nüßler Dirk , Pohl Nils 
Published: October 2017

Abstract
This paper presents the development of a novel line-camera device in the lower THz-domain which is capable of measuring minute differences in broadband spectral fingerprints of non-conducting materials. The primary focus is sorting black plastics in industrial recycling contexts, where large scale sorting of different types of black plastics remains a challenge. The system operates between 84 GHz and 96 GHz. As the relevant plastics exhibit no specific absorption lines in this frequency range, a broadband approach is necessary to accumulate slight differences in dielectric properties. Using this technique, enough entropy can be gathered that a machine learning algorithm can be trained to differentiate between different materials. This has to work even in the presence of contaminants such as flame retardants, color pigments and dirt. Preliminary results suggest that the THz sensor system is capable of achieving these goals.
Cardiac tamponade in a patient with autoimmune polyglandular syndrome type 2
Authors: Vryonidou Andromachi , Paschou Stavroula A , Dimitropoulou Fotini , Anagnostis Panagiotis , Tzavara Vasiliki , Katsivas Apostolos 
Published: October 2017

SummaryWe describe a case of a 40-year-old woman who was admitted to the intensive care unit with a rapid onset of dyspnea and orthopnea. She presented progressive weakness, weight loss and secondary amenorrhea during last year, while intermittent fever was present for the last two months. Initial biochemical evaluation showed anemia, hyponatremia and increased C-reactive protein levels. Clinical and echocardiographic evaluation revealed cardiac tamponade, which was treated with pericardiocentesis. Pleural fluid samples were negative for malignancy, tuberculosis or bacterial infection. Hormonal and serologic evaluation led to the diagnosis of autoimmune polyglandular syndrome (APS) type 2 (including primary adrenal insufficiency and autoimmune thyroiditis), possibly coexisting with systemic lupus erythematosus. After symptomatic rheumatologic treatment followed by replacement therapy with hydrocortisone and fludrocortisone, the patient fully recovered. In patients with the combination of polyserositis, cardiac tamponade and persistent hyponatremia, possible coexistence of rheumatologic and autoimmune endocrine disease, mainly adrenal insufficiency, should be considered. Early diagnosis and non-invasive treatment can be life-saving.Learning points:In patients with the combination of polyserositis, cardiac tamponade and persistent hyponatremia, possible coexistence of rheumatologic and autoimmune endocrine disease, mainly adrenal insufficiency, should be considered.Early diagnosis and non-invasive treatment can be life-saving for these patients.Primary adrenal insufficiency requires lifelong replacement therapy with oral administration of 15–25 mg hydrocortisone in split doses and 50–200 µg fludrocortisone once daily.
Metalenguaje y metaorganización en la lingüística sistémico-funcional
Authors: González de Requena Farré Juan Antonio 
Published: October 2017

Este artículo pretende llevar a cabo una revisión teórica de la problemática del metalenguaje en la lingüística sistémico-funcional y propone una reducción funcional de la terminología metalingüística presente en la ciencia del lenguaje contemporánea. Desde una perspectiva sistémico-funcional, el lenguaje aparece como un sistema metaorganizado en virtud de ciertas dimensiones metafuncionales (ideacional, interpersonal y textual) y de una estratificación de planos de realización (semántico-discursiva, léxico-gramatical y fonológica-grafológica) basada en relaciones de metarredundancia. En ese sentido, se exploran las opciones de reducir los rendimientos metalingüísticos, metacomunicactivos y metadiscursivos a la gramática constitutiva del lenguaje natural, sin que sea precisa la escisión recursiva de un metalenguaje formalizado de orden superior o de algún metacódigo acotado.
Autológ haemopoeticus őssejt-transzplantáció szerepe T-sejtes lymphomában. Magyar adatok
Authors: Szomor Árpád , Csalódi Renáta , Kosztolányi Szabolcs , Nagy Ágnes , Pammer Judit , Tóth Orsolya , Losonczy Hajna , Alizadeh Hussain , Miltényi Zsófia , Reményi Péter , Piukovics Klára 
Published: October 2017

Abstract: T-cell lymphoma is a poor prognostic hematological malignancy. The generally used – not sufficiently effective – induction chemotherapy should be improved with consolidative autologous hemopoetic stem cell transplantation. The authors describe the role, place and effectiveness of transplantation in this disorder. One hundred thirty three autologous stem cell transplantations were performed in the last 22 years in Hungary. Detailed results are available from the last 6 years. In this period 43 transplantations were carried out in 4 Hungarian centers. Carmustine-etoposide-cytosine arabinoside-melphalan (BEAM) conditioning regimen was used in 95%. The transplantation was done mainly in complete remission (84%), 1 year after transplantation 65% of patients were still in complete remission. Eleven patients died, 82% of them have progressive disease. Brentuximab vedotin has already proved the effectiveness, several other chemoterapeutics, monoclonal antibodies, kinase inhibitors are under investigation. In certain cases allogeneic stem cell transplantation has real indication among therapeutic options. Orv Hetil. 2017; 158(41): 1615–1619.
Thalidomidkezelés relabált, diffúz nagy B-sejtes lymphomában idős betegekben. Három eset bemutatása
Authors: Wohner Nikolett , Varga Gergely , Szloboda Péter , Farkas Péter , Masszi András , Horváth Laura , Szombath Gergely , Várkonyi Judit , Benedek Szabolcs , Masszi Tamás 
Published: October 2017

Abstract: Diffuse large B-cell lymphoma (DLBCL), a high-grade lymphoproliferative disease, is the most common lymphoma in adults, representing 31% of non-Hodgkin lymphomas (NHL). In elderly patients treatment is problematic because of the high toxicity of standard chemotherapy protocols, especially in relapsed cases, where high-dose chemotherapy and haematopoietic stem cell transplantation would be the best choice. More and more data is becoming available on alternative treatment of refractory/relapsed NHL, including studies on the positive effect of thalidomide and second generation IMiDs in DLBCL, which are already part of the standard treatment protocol in myeloma multiplex and myelodysplasia. The broadening use of IMiDs is due to their anti-angiogenetic, immunmodulatory and anti-inflammatory properties. In addition, a component of the E3-ubiquitin ligase complex, named cereblon, has been described in 2010 as the molecular effector of the thalidomide signal transduction pathway. We initiated thalidomide treatment in three elderly patients with relapsed DLBCL. In two cases, patients had CNS involvement, in the third case the patient had primary mediastinal disease. Patients received 100 mg thalidomide in combination with corticosteroids. Two patients showed an excellent response reaching complete remission on imaging; these patients are progression-free 12 and 20 months after the beginning of treatment. One patient with CNS involvement progressed and deceased despite therapy. According to the literature, IMiDs have significant activity in relapsed DLBCL. Our case-report presents promising results in an elderly patient population with aggressive relapsed NHL that usually has very poor outcome, as high-toxicity treatment cannot be given to these patients. Consequently, because of its efficiency, low-cost and low-toxicity, it is recommended to consider thalidomide therapy in elderly patients with high-grade DLBCL. Orv Hetil. 2017; 158(41): 1642–1648.
The Establishment of the 3rd National Reference Standard for Tachypleus Tridentatus Lysate
Authors: Cai Tong , Zhang Guolai , Pei Yusheng , Gao Hua 
Published: October 2017

<p><strong>Objective</strong> To establish the 3rd national reference standard for Tachypleus Tridentatus Lysate Reagent. <strong>Method</strong> <strong>and Results</strong> The candidates of reference standard were studied for the physical and chemical properties, and the stability. To determined its sensitivity by collaboration calibration. <strong>Conclusions</strong> The sensitivity of the 3rd national reference standard for TAL is 0.06EU / ml, lot number is 150603-201003.</p>
Characterization of Ultrahigh-Molecular-Weight Oilfield Polyacrylamides Under Different pH Environments by Use of Asymmetrical-Flow Field-Flow Fractionation and Multiangle-Light-Scattering Detector
Authors: Dalsania Yogesh , Doda Ankit , Trivedi Japan 
Published: October 2017

Summary
Various types of ultrahigh-molar-mass polyacrylamides (HPAMs) and their copolymers and terpolymers used not only in enhanced oil recovery (EOR) but also in drilling, fracturing, water treatment, and tailing applications require an accurate description of polymer molar mass (Mw) and hydrodynamic size for their optimal design. The range of Mw for various types of available HPAMs is between 4 and 30 million g/mol and is typically determined by use of intrinsic-viscosity measurement.
Molecular-weight distribution (MWD) cannot be determined because neither standard with low polydispersity index (PDI) nor gel-permeation-chromatography (GPC) or size-exclusion-chromatography (SEC) techniques exist today for such ultrahigh-molar-mass polymers. Moreover, the solution environment in underground reservoirs, characterized by high temperatures, pH values, and the presence of monovalent and divalent ions, may often lead to changes in polymer-macromolecular conformation. Current techniques, SEC, ultraviolet-visible measurements, and liquid chromatography, are not capable of accurately investigating these complex macromolecular structures for various reasons. In this paper, the asymmetrical-flow field-flow fractionation (AF4) system was used to fractionate four different ultrahigh-molecular-weight HPAM samples, varying in molar mass and commercially used for oilfield applications, in various carrier pH values ranging from 12 to 3 (pH values of 12, 7.4, and 3). The system uses field-flow fractionation (FFF), a family of analytical techniques developed specifically for separating and characterizing macromolecules, colloids, and particles. The theoretical separation range for AF4 is between 103 to 1012 g/mol. Other advantages over conventional GPC/SEC include minimum shear degradation, mild operating conditions, and no sample loss caused by adsorption. The flow system was equipped with a multiangle-light-scattering (MALS) and refractive-index (RI) detectors to measure molar mass and radius of gyration (Rg).
The results show that the observed molecular weight of the polymer aggregate increased substantially as the pH value of the carrier solution decreased from 12 to 3, especially for higher-molar-mass polymers. The sample Rg showed the opposite trend, decreasing as the pH of the carrier solution changed from basic to acidic. For ultrahigh molecular HPAM at high pH, a narrower molar mass and radius distribution was observed with disaggregated molar mass and increased branching or swelling (therefore larger hydrodynamic radius). Use of this direct separation and measurement technique can improve understanding of polymer-macromolecular structure and corresponding changes in the reservoir brines.
In Vitro Cytotoxic Activities of Platinum(II) Complex with 1-Methyl-2-(3'- hydroxypropyl)benzimidazole and 2-(3'-Hydroxypropyl)benzimidazolium Hexa- and Tetrachloroplatinate Salts
Authors: Eren Gokcen , Yilmaz Sukran , Gumus Fatma 
Published: October 2017

Background:
Platinum complexes as antitumor agents have received considerable attention
due to the clinically approved and have been marketed worldwide such as cisplatin, carboplatin,
oxaliplatin or marketed locally such as nedaplatin, lobaplatin and heptaplatin for treatment
of various tumor diseases. However, those drugs still had their own defects and they exhibited side
effects including nephrotoxicity, ototoxicity, neurotoxicity and bone marrow suppression. Therefore
there is still continuing interest in the development of new platinum drugs avoiding their inherent
resistance and toxicity.

Methods:
Two hexa- and tetrachloroplatinate salts and one platinum(II) complex were synthesized
and evaluated for their in vitro cytotoxicities against human HeLa, MCF-7, and MDA-MB-231 cell
lines by the MTT assay.

Results:
The growth inhibitory effect values of compounds 1-3, and cisplatin against the cell lines
were expressed as inhibition %.

Conclusion:
Compound 3 showed appreciable activity for all examined cell lines compared to that
of reference compound cisplatin.
Exploring the Therapeutic Affordances of Self-Harm Online Support Communities: An Online Survey of Members
Authors: Coulson Neil S , Bullock Emma , Rodham Karen 
Published: October 2017

Background
A growing number of online communities have been established to support those who self-harm. However, little is known about the therapeutic affordances arising from engagement with these communities and resulting outcomes.

Objective
The aim of this study was to explore the presence of therapeutic affordances as reported by members of self-harm online support communities.

Methods
In total, 94 respondents (aged 13-63 years, mean=23.5 years; 94% female) completed an online survey exploring their experiences of engaging with a self-harm online support community. Respondents varied in terms of how long they had been accessing an online community, with 22% (21/94) accessing less than 1 year, 39% (37/94) 1 to 2 years, 14% (13/94) 2 to 3 years, and 24.5% (23/94) more than 3 years. Responses were analyzed using deductive thematic analysis.

Results
The results of our analysis describe each of the five therapeutic affordances that were present in the data, namely (1) connection, the ability to make contact with others who self-harm for the purposes of mutual support and in so doing reduce feelings of loneliness and isolation; (2) adaptation, that is, how use of online support varies in relation to the personal circumstances of the individual user; (3) exploration, that is, the ability to learn about self-harm and learn about strategies to reduce or stop self-harming behavior; (4) narration, that is, the ability to share experiences, as well as read about the experiences of others; and (5) self-presentation, that is, how and what users present about themselves to others in the online community.

Conclusions
Our findings suggest that engagement with self-harm online support communities may confer a range of therapeutic benefits for some users, which may serve to minimize the psychosocial burden of self-harm and promote positive coping strategies. In addition, the online nature of the support available may be helpful to those who are unable to access face-to-face support.