bluuebunny/crossref_metadata_2025_split huggingface dataset:
Volume, conductance, and scatter parameters of neoplastic and nonneoplastic lymphocytes using Coulter LH780
Authors: Choccalingam Chidambharam 
Published: January 2018

Abstract
PURPOSE: Automated hematology analyzers yield a complete hematological profile including a complete blood count and a differential white blood cell count. The differential count is based on analyses of three parameters, namely, volume, conductance, and scatter (VCS). We aimed to evaluate the VCS parameters, histograms, and scatterplots of neoplastic and nonneoplastic lymphocytes.
MATERIAL AND METHODS: Patients were grouped into four categories, namely, acute lymphoblastic leukemia (ALL), chronic systemic disorders, chronic lymphocytic leukemia (CLL), and acute viral disease. Lymphocytes from all four groups were compared with lymphocytes from normal participants.
RESULTS AND CONCLUSIONS: The histogram for acute viral disease showed a trough at T1, which was slightly obliterated, and the F1 curve mildly extended to the right. The T1 for ALL was replaced with a peak at >40% of the preset limit. The F1 peak was shifted to left for CLL. The scatterplot for viral disease showed lymphocytes extending to the variant lymphocyte window. The lymphocytes of ALL extended to the blast window, with both increase in volume and mild increase in scatter. The lymphocytes in CLL were smaller and located below the normal lymphocyte region. Mean lymphocyte volume was significantly increased in ALL and was significantly decreased in CLL. Mean lymphocyte conductance was significantly increased in CLL and significantly decreased in both acute viral disease and ALL. Mean lymphocyte scatter was significantly decreased in acute viral disease and significantly increased in ALL.
Development of a dry-reagent mix-based polymerase chain reaction as a novel tool for the identification of Acinetobacter species and its comparison with conventional polymerase chain reaction
Authors: Kulkarni Raghavendra D. , Mishra Mukti Nath , Mohanraj Jeevanandam , Chandrasekhar Arun , Ajantha G S. , Kulkani Sheetal , Bhat Shama 
Published: January 2018

Abstract
BACKGROUND: Nosocomial infections are often caused by multidrug-resistant bacteria and the incidence is increasing. Acinetobacter, a Gram-negative bacillus, is commonly associated with the use of intravascular catheterization and airway intubation. Polymerase chain reaction (PCR) for identification of Acinetobacter baumannii	from samples has been standardized that use conventional wet-reagent mix. We have designed and optimized a dry-reagent mix for identification of Acinetobacter species by PCR. The dry-reagent mix can be stored at room temperature, has less chances of contamination, and thus can be used at point-of-care diagnosis.
AIM AND OBJECTIVE: The present work was focused on comparing the sensitivity and specificity of dry-reagent PCR mix over conventional wet-reagent PCR mix for identification of Acinetobacter species.
MATERIALS AND METHODS: Conventional wet-reagent mix based and dry-reagent mix based PCR were carried out for the DNA isolated from Acinetobacter species. The latter was also applied directly on bacterial growth without prior DNA extraction process. Equal numbers of bacterial isolates other than Acinetobacter species were also subjected to identification by the same protocols for determining the sensitivity and specificity of the test.
RESULTS: The Acinetobacter species showed amplification of the target rpoB gene and the band was observed at 397 bp. The dry-reagent PCR mix results matched completely with the conventional wet-reagent PCR mix assay. All the non-Acinetobacter isolates were negative for the PCR. This indicates that the test is highly specific. The dry-reagent mix also contained an enzyme resistant to PCR inhibitors and capable of amplifying DNA directly from cells.
CONCLUSION: Performance of dry-reagent PCR mix without the need for DNA extraction and preparation of a PCR mix proved to be more sensitive and reduce the handling error, minimizes the time, manual work, and skilled labor.
Dilute antiferromagnetism in magnetically doped phosphorene
Authors: Allerdt Andrew , Feiguin Adrian E. 
Published: December 2017

We study the competition between Kondo physics and indirect exchange on monolayer black phos-phorous using a realistic description of the band structure in combination with the density matrixrenormalization group (DMRG) method. The Hamiltonian is reduced to a one-dimensional problemvia an exact canonical transformation that makes it amenable to DMRG calculations, yielding exactresults that fully incorporate the many-body physics. We find that a perturbative description of theproblem is not appropriate and cannot account for the slow decay of the correlations and the completelack of ferromagnetism. In addition, at some particular distances, the impurities decouple formingtheir own independent Kondo states. This can be predicted from the nodes of the Lindhard function.Our results indicate a possible route toward realizing dilute anti-ferromagnetism in phosphorene.
Received: 19 September 2017, Accepted: 12 October 2017; Edited by: K. Hallberg; DOI: http://dx.doi.org/10.4279/PIP.090008
Cite as: A Allerdt, A E Feiguin, Papers in Physics 9, 090008 (2017)
This paper, by A Allerdt, A E Feiguin, is licensed under the Creative Commons Attribution License 3.0.
N-(Dibenzylcarbamothioyl)-3-methylbutanamide: Crystal structure, Hirshfeld surfaces and antimicrobial activity
Authors: Gumus Ilkay , Gonca Serpil , Arslan Birdal , Keskin Ebru , Solmaz Ummuhan , Arslan Hakan 
Published: December 2017

The compound N-(dibenzylcarbamothioyl)-3-methylbutanamide as a thiourea derivative was synthesized and structurally characterized by NMR and FT-IR spectroscopic techniques. The molecular structure of compound was also characterized by single crystal X-ray diffraction method. Crystal data for title compound C20H24N2OS: monoclinic, space group C2/c (no. 15), a = 19.6882(9) Å, b = 9.4045(4) Å, c = 19.5012(8) Å, β = 98.433(2)°, V = 3571.8(3) Å3, Z = 8, μ(CuKα) = 1.665 mm-1, 25057 reflections measured (9.168° ≤ 2Θ ≤ 144.196°), 3500 unique (Rint = 0.0322, Rsigma = 0.0200) which were used in all calculations. The final R1 was 0.0363 (I>2σ(I)) and wR2 was 0.0910 (all data). Intermolecular contacts obtained from X-ray single crystal diffraction study were also explored using both Hirshfeld surfaces and fingerprint plots. Hirshfeld surface analysis showed the occurrence of S···H, O···H and H···H contacts that display an important role to crystal packing stabilization of the thiourea derivative compound. In addition, the compound was evaluated for both their in-vitro antibacterial and antifungal activity.
Valuing new medicines in the early 21:st century
Authors: Steen Carlsson Katarina , Jönsson Bengt 
Published: January 2018

What is the actual value of new medicines? The answer to this question is the key to rational use of new technologies in health care and for design of appropriate incentives for innovation. In this paper we present methods, data and study results for valuing new medical technologies in a life cycle perspective, relevant for development of a new approach to contract and payment for innovation that can replace present systems for pricing and reimbursement. Focus is on value in clinical practice, and on the data needs and methods needed for the development of outcome-based payment systems that balances risks and rewards for innovation in health care. We provide an overview of studies from the Swedish context on the value of new medicines introduced in the treatment of diabetes, cancer, cardiovascular disease and rheumatoid arthritis. These studies using national health data and quality registers emphasise the importance of continuing efforts to collect relevant data for assessment of value after a medicine reaches the market and starts to be used in clinical practice. It is only when medicines are used in clinical practice that the benefits for real-world patient populations can be identified, measured and valued. Analyses of real-world data will also assist further development and tailoring of treatment strategies to optimize the value of the new technology. While an effective patent system rewards innovation for a limited period of time, many innovations may continue to provide value to society long after patent protection, and these values must be included in the assessment of value of innovation.
Toplumun Devrik Cümle Hakkındaki Düşüncesi ve Nesirde Devrik Cümlenin Yeri / Opinion of Society on the Inverted Sentence and the Place of the Inverted Sentence in Prose
Authors: Küçük Serhat , Avcı Yusuf , Şengül Ebru 
Published: December 2017

<p><strong>Abstract</strong></p><p>This study aims to analyse the usage of inverted sentences which we have been witnessing in daily life, language and literature as well as show public perception about the inverted sentences. In the research, eight proses by eight different Turkish writers have been analysed according six factors. The observed data showed that inverted sentences more likely to be used by so-called left-wing writers who wrote about social subjects.</p><p>To collect data about public opinion, a survey, consisting of 12 questions and answered by 500 people, conducted by the researchers. Regarding the last question, which serves most for the work, 772 connotations have been indicated by 448 people and these connotations have been associated with 267 different terms. According to data gathered by the open-ended questions, it could be said that society is in a dilemma as well as linguists. That we have come across different terms in addition to positive and negative answers shows the wealthy world of thought in Turkish society.</p><p><strong>ÖZ</strong></p><p>Bu araştırma, son yıllarda günlük hayatımızda gerek iletişimimizde gerek okuyup yazdıklarımızda sık sık karşılaştığımız devrik cümle kullanımını ve bunun toplum tarafından algılanış biçimini incelemeyi amaçlamaktadır. Araştırmada, sekiz Türk yazarın nesirlerinde devrik cümle kullanımları 6 faktör açısından incelenerek elde edilen veriler ışığında devrik cümleyle ilgili düşünce tarzları ortaya konulmaya çalışılmıştır. Elde edilen bulgular, toplumsal konularda yazılar yazan ve solcu olarak nitelendirilen yazarların devrik cümle kullanım oranlarının daha yüksek olduğunu göstermiştir.</p><p>Araştırmada, devrik cümle yapısı ile ilgili toplum algısını ölçmek amacıyla 500 katılımcının cevapladığı 12 soruluk bir anket çalışmasının sonuçlarına da yer verilmiştir. Çalışmanın amacına en çok hizmet eden son soruya; 448 katılımcıdan 772 çağrışım belirtilmiş, bu çağrışımlar 267 farklı kavramla ilişkilendirilmiştir. Açık uçlu sorudan elde ettiğimiz verilere göre toplumun da tıpkı dilciler gibi devrik cümle hakkında ikileme düşmüş olduğu tespit edilmiştir. Olumlu ve olumsuz yanıtların yanında çeşitli kavramlara rastlamamız toplumumuzun zengin düşünce gücünü göstermektedir. </p>
Ergenlerin Akrana Bağlanma Stillerinin Umutsuzluk Düzeyleri İle İlişkisinin İncelenmesi / Examining the Correlation of the Peer-Attachment Styles with Hopelessness Levels in Adolescents
Authors: Kanak Mehmet , Bilbay Asuman , Balta Dursun 
Published: December 2017

<p>The purpose of this study is to examine the correlation between the peer attachment styles and hopelessness levels in adolescents. The research was a descriptive study based on correlational survey model. The population of the study consisted of a total of 213 students studying in the 6th, 7th, and 8th grades of Erzincan Otlukbeli Fatih Secondary School, and the 9th, 10th, 11th, and 12th grades of Otlukbeli Multi-program Anatolian High School. The data were collected by using the “Beck Hopelessness Scale” (BHS) developed by Beck, Lester and Trexler (1974) to determine the hopelessness levels of the students, and the “Adolescent Friendship Scale” (AFS) developed by Wilkinson (2008) and adapted into Turkish by Ercan (2015) in order to determine the peer attachment styles of adolescents.</p><p>As a result of the analyses carried out in order to determine the hopelessness levels of the participants based on gender and level of teaching, it was observed that there was no significant difference on hopelessness levels in terms of gender (p&gt;.05); on the other hand, the hopelessness scores of high school students were higher compared to secondary school students in terms of level of teaching (p&lt;.05).</p><p>The peer attachment styles of the participants in terms of gender and level of teaching were determined by using t test. As a result of these analyses, it was observed that there was no significant difference in the subscales of attachment styles in terms of gender (secure, avoidant, anxious/ambivalent) (p&gt;.05), there was a significant difference between the mean scores obtained by the secondary school students from Secure Attachment and Avoidant Attachment subscales of the Adolescent Friendship Scale in terms of level of teaching (p&lt;.05); and there was no significant difference between their mean scores of Anxious/ambivalent Attachment subscale (p&gt;.05).</p><p>Pearson Product-Moment Correlation test was used for examining the correlation between peer attachment styles and hopelessness levels of the participants. As a result of the analysis, it was observed that while there was a negative significant correlation between total score of hopelessness level and the secure attachment subscale (p&lt;05), there was no significant correlation between total score of hopelessness level and avoidant and anxious/ambivalent attachment subscales of the participants (p&gt;05). </p><p>As a result of the study, recommendations were offered to the researchers and the staff members working in the field in accordance with the results obtained. </p>
Foucault’un İktidar Görüşleri Işığında Erdal Öz’ün Yaralısın Romanı / Yaralisin, the Novel by Erdal Oz, in the Light of Foucault’s Power Theory
Authors: Üstün Koray 
Published: December 2017

<p><strong>Abstract</strong></p><p>In the light of the power concepts theorized by Michel Foucault, this article investigates Erdal Oz's novel Yaralisin (You’re Wounded). Foucault’s power structure that systematized in Subject and Power (1961), History of Sexuality (1984), Birth of Prison (1975), The Birth of Biopolitics (2004), has similarities with crime production that the novel reflects. Accordingly, individuals are being standardized in the prison through programs, strategies and technics that the power structure determined. In this process, there is no direct enforcement on the individual. The power structure connects the individual to itself through knowledge and body. In Oz’s novel the subject depending on space changing are being standardized and transformed into the “Nuri” character, as we read in the text. At the base of becoming standard individual through lost of identity, there is crime production. As for crime production, it takes shape in accordance with space. In the novel, space dependent suffering, inflicted on individuals, places the subject on a hierarchical plane, as Foucault has also indicated, and brings an end to existence. The power structure, cutting off the individual from his private space, taking him first into the interrogation room, and then to the prison, has made him a part of the system and has objectified him. The digestive effect of the power structure has become even more concrete with the presence of the second person narrator within the narrative plane; depersonalization has taken place within the new order.</p><p><strong>Öz</strong></p><p>Bu makalede Michel Foucault’un kuramsallaştırdığı iktidar kavramı ışığında Erdal Öz’ün <em>Yaralısın</em> romanı incelenmiştir. Foucault’nun <em>Özne ve İktidar </em>(1961),<em> Cinselliğin Tarihi </em>(1984)<em>, Hapishanenin Doğuşu </em>(1975)<em>, Biyopolitikanın Doğuşu</em> (2004) gibi kitaplarında sistemleştirdiği iktidar, romanda aktarılan suç üretimi ile paralellik taşımaktadır. Bireyler, iktidar tarafından belirlenen program, strateji ve tekniklerle hapishanelerde tek tipleştirilmektedir. Bu süreçte bireyler üzerine doğrudan bir yaptırım uygulanmaz; iktidar, bilgi ve beden yönetimi üzerinden bireyi kendine bağlar. Öz’ün romanında da uzamsal değişimlere bağlı olarak tekil özneler, tek tipleştirilerek metindeki karşılığıyla “Nuri”lere dönüşür. Bireyin kendi kimliğini yitirerek tek tipleşmesinin temelinde suç üretimi vardır. Suç üretimi ise uzama göre şekillenir. Romanda uzama göre değişen çektirilen azaplar, Foucault’un da belirttiği gibi özneyi hiyerarşik düzleme yerleştirir ve varoluşu sona erdirir. İktidar, özneyi kişisel mekânından ayırıp önce sorgu odasına ardından da hapishaneye götürerek onu düzenin bir parçası hâline getirmiş ve nesneleştirmiştir. İktidarın sindirici etkisi, anlatı düzlemindeki ikinci tekil anlatıcının varlığıyla daha da somutlaşmış; kurulan düzen içerisinde özne yitimi gerçekleşmiştir. </p>
Türkiye Türkçesinde -ma Ekinin Yapım Eki Olarak İşlevleri / Functions of the Derivative Suffix -ma in Turkey Turkish
Authors: Bayraktar Erten Nesrin 
Published: December 2017

<p><strong>Abstract</strong></p><p>Functions of the suffix -ma suffix can be classified under three groups in Turkey Turkish. This suffix produces adjectives that are related with root meanings like dönme dolap, sallama çay, gömme dolap, and adjectives like bodoslama atla, silme doldur etc. Besides these functions, it produces permanent nouns like gözleme, sarma, dolma, dondurma, kuzukapama, sürme, etc. This study investigates the suffix -ma as a derivational form and its functions have been classified. The study also evaluates the frequency with which it is used to coin permanent nouns and adjectives. </p><p> <strong>Öz</strong></p><p>-ma ekinin Türkiye Türkçesinde işlevlerini başlıca üç grupta toplamak mümkündür. -ma eki ile bir yandan dönme dolap, sallama çay, gömme dolap gibi örneklerde eklendiği eylem tabanıyla ilişkili sıfatlar ve bodoslama atla, silme doldur gibi zarflar yapılırken, öte yandan da gözleme, sarma, dolma, dondurma, kuzukapama, sürme örneklerinde görüldüğü gibi kalıcı adlar yapılmıştır. Kalıcı adlar içinde yemek adları, oldukça önemli bir yer tutmaktadır. Bu çalışmada -ma eki, bir yapım eki olarak değerlendirilecek ve örnekler çerçevesinde tasnif edilerek kalıcı ad ve sıfat yapımında kullanıldığı yerlerdeki sıklık ele alınacaktır.</p>
Practices of farmers in production and marketing of tomato in Nsukka Local Government Area of Enugu State, Nigeria
Authors: Iwuchukwu Juliana , Nwobodo Cynthia , Ugwuja Emmanuel I. 
Published: December 2017

The study described socio-economic characteristics, production, consumption and marketing patterns of tomato farmers as well as constraints they encounter in tomato production in Nsukka Local Government Area of Enugu State, Nigeria. One hundred and twenty tomato farmers randomly selected form twelve villages in the area constituted sample for the study. Data were collected with interview schedule and questionnaire and were presented with frequency, percentage and mean scores. Findings show that the respondents were mainly married (71%) women (72.5%) who were literate with mean age and mean farming experience of 42.22 years and 17.21years respectively. Greater proportion of the respondents grew tomatoes on communal land (31.7%) with personal savings (42.5%) and hired labour (45%). They grew tomatoes during rainy season (54.1%) using personal reserved seeds (53.3%). Lack/poor storage facility (M=2.00) and fluctuation in price of tomato (M = 2.13) were some of the serious constraints to production and marketing of tomatoes respectively in the area. The study recommends that government, non-governmental organisations, self help development organisations/agencies as well as philanthropists should assist in provision of storage facilities for tomatoes so as to reduce losses and ensure preservation and availability of the product all year round at reasonable and stable price.
Normothermic Regional Perfusion Experience of Organ Procurement Organizations in the US
Authors: Sellers Marty T. , Philip Jennifer L. , Brubaker Aleah L. , Cauwels Roxane L. , Croome Kristopher P. , Hoffman Jordan R. , Neidlinger Nikole A. , Reynolds Andrea M. , Wall Anji E. , Edwards John M. 
Published: October 2024

ImportanceDespite the unmet need for donor organs, organ use from donation after circulatory determination of death (DCD) donors has been limited by inferior transplant outcomes. Normothermic regional perfusion (NRP) improves recipient outcomes and organ utilization from DCD donors. There is variability in NRP policies and experience among US organ procurement organizations (OPOs).ObjectivesTo determine OPO experience, identify operational inconsistencies, and explore needs related to NRP.Design, Setting, and ParticipantsThis survey study included 55 OPOs in the US that had recovered DCD organs and completed a survey on operational, administrative, and educational components related to NRP in November to December 2023. Data analysis was performed from February to April 2024.Main Outcome and MeasuresThe primary outcome was the number of OPOs participating in and/or anticipating NRP participation. Secondary outcomes were NRP implementation barriers, OPO education practices, and future needs regarding consensus NRP recommendations and standards.ResultsOf 55 respondents, 11 (20%) were chief executive officers, 8 (15%) were chief operating officers, and 36 (65%) were medical directors or chief clinical officers. Forty-nine OPOs facilitated NRP cases: 26 OPOs (53%) facilitated both thoracoabdominal NRP (TA-NRP) and abdominal NRP (A-NRP) cases, 16 OPOs (33%) facilitated only TA-NRP, and 7 OPOs (14%) facilitated only A-NRP. OPOs reported 606 NRP cases (421 TA-NRP [69%], 185 A-NRP [31%]); median (range) case experience was 8 (1-52). Fifty-two of 55 OPOs (95%) thought standardized guidance documents would be helpful. All 49 OPOs facilitated NRP at a transplant center’s request; 39 (80%) had NRP initiated by a nonlocal transplant center. Twenty-three of 49 OPOs (47%) participated in NRP without a policy and without a policy pending approval. Positive donor hospital feedback was received by 29 OPOs (59%), primarily focused on increased organs transplanted and prerecovery communication. Allocation challenges were experienced by 21 OPOs (43%); their median (range) case volume was higher than those with no reported allocation challenges (11 [3-52] vs 6.5 [1-29]; P = .03). Eleven OPOs (22%) had incorporated NRP into general donor hospital education.ConclusionsIn this survey study of US OPOs, wide variation existed with respect to NRP experience and practice. Allocation challenges occurred more frequently with increased NRP experience. NRP guidelines and standardization were desired by most OPOs to decrease allocation challenges and maximize the gift of organ donation.
Instantaneous Tiltmeter Triggered by Dynamic Wetting Behavior
Authors: Zhan Fei , Li Nan , Wang Lei , Wang Shuizhong , Liu Jing , Song Guoyong 
Published: October 2024

AbstractA novel instantaneous tiltmeter with dynamic and static monitoring functions is reported that is based on liquid metal dynamic wetting behavior in a bio‐fabricated anisotropic microchannel. The proposed system achieves instantaneous tiltmeter functionality, offering a broad detection range (−90°–90°) with high precision (0.05°), a rapid reaction time (0.11 s), and enhanced durability. Moreover, a seamless integration has enabled water wave detection, language programming, and human limb monitoring. Especially, the integration of tiltmeter and a 3D motion platform results in a surface structure scanning system capable of effectively performing large area (>200 cm2) and height difference scanning functions. This innovative approach holds great potential for transformative changes in the fields of advanced manufacturing, flexible robotics, and the flexible sensing, further facilitating widespread adoption.