bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploration of the coefficients of correlation of different segmental measurements with total length of disarticulated femoral bones: a systematic review
Authors: Khanal L. , Shah S. , Koirala S. 
Published: July 2017

Abstract
Introduction: In a forensic case with availability of femoral fragments, estimation of the total femoral length of the available segment is one of the steps used for estimating an inidividual's stature. This estimation will be more accurate if the segment has a high coefficient of correlation with the total length of the femur. This article reviews the coefficients of correlation of different segmental measurements with femur length. Materials and Methods: Seventeen articles were selected from PubMed, Google Scholar and other public research sharing sites. Articles with coefficients of correlation of segmental measurements with the total length of the femur were included in the study. Results and Discussion: Among the 17 articles, two were related to measurement of the proximal part of the femur only, one was concerned with femoral shaft measurement only, 7 focus on the distal part only, 3 concerned both proximal and distal parts, and 4 articles included all parts of the femur. Sample sizes varied from 50 to 2388 femur bones. The value of the coefficient of correlation (‘r’) was found to vary with respect to gender and nationality. The value of ‘r’ for several width measurements of the segments had a higher correlation among females compared to male individuals. Conclusion: Though segment 1 of the proximal part, segment 3 of the shaft, and the epicondylar and bicondylar breadths of the distal part of the femur are highly correlated with the total length of femur, an investigator should also consider of gender, race, ethnicity and environmental factors when choosing the femur segment that has the highest value of ‘r’.
A report on the accessory head of Flexor Pollicis Longus and Variations of Forearm Musculature
Authors: Hafez S. 
Published: July 2017

Abstract
Introduction: Gantzer's muscle has drawn attention from several authors owing to the possibility of interosseous nerve compression. This is a report of an accessory head of flexor pollicis longus (FPL, a variant of Gantzer's muscle) and a review of the variations of all muscles of the forearm. Materials and Methods: An accessory head of FPL was discovered in both the right and left antebrachial regions during a cadaver dissection. The muscle was dissected and photographed. Results: The anatomical variation I report is a slender conical muscle joining the FPL. Its origin merged with fibers of the flexor digitorum superficialis. It inserted into the upper part of the middle third of the forearm by joining the medial tendinous part of the FPL; this join was by means of a short cylindrical tendon. The reported muscle was innervated by the anterior interosseous nerve, which was seen to be present posterolateral to the muscle in both forearms. Conclusion: The described muscle might cause pressure problems to the underlying structures especially the anterior interosseous nerve. Variations must be considered during surgical intervention to avoid unintentional damage to healthy tendons. In addition, accessory tendons can potentially be useful in the repair or replacement of damaged tendons through surgical transfer or transplantation. Variations of muscles, especially accessory muscles, may mimic the behavior of soft tissue tumors and can result in nerve compressions. This collection of variations of the forearm musculature will be useful to surgeons in practice as well as students in dissection labs.
Anatomical studies on the cranial and caudal mesenteric arteries of the Barbados Black Belly sheep
Authors: Mohamed R. 
Published: July 2017

Abstract
Introduction: The Barbados Black Belly is a breed of domestic sheep in the Caribbean island of Trinidad. Anatomical studies on the cranial and caudal mesenteric arteries are necessary to know the pattern of its blood supply to gain information in benefit of experimental surgery. Materials and Methods: The thoracic part of the aorta of five sheep was injected with red latex. Careful gross dissection of the cranial and caudal mesenteric arteries was performed either after embedding in 10% formalin solution for 2-3 days. Results: The cranial mesenteric artery originated from the abdominal aorta, caudally to the celiac trunk, giving caudal duodenal artery, jejunal arteries, ileal arteries, ileocolic artery and middle colic artery. The caudal mesenteric artery arises from the aorta, cranially to the external iliac arteries, originating the left colic and cranial rectal arteries. Conclusion: cranial and caudal mesenteric arteries supplied the small and large intestine of the Barbados Black Belly sheep except caudal part of the large intestine which were supplied by the middle and caudal rectal arteries.
β-hydroxy-β-methylbutyrate (HMβ), Physical training and skeletal muscle: a systematic review
Authors: Gonçalves L. , Madureira D. , Santana J. , França E. , Miranda M. , Souza R. , Caperuto E. 
Published: July 2017

AbstractSkeletal muscle mass gain is beneficial in several situations. It improves athlete's performance and quality of life in pathological situations. The existence of different methods that are able to increase muscle mass brings up discussions about nutritional supplements use on physically active individuals. β-hydroxy-β-methylbutyrate is a Leucine metabolite and it's believed to have an anticatabolic effect with different results depending on the type of exercise done. Objective: The objective of this research was to identify and categorize the methodological features and results of β-hydroxy-β-methylbutyrate (HMβ) studies, physical exercise and its effects on skeletal muscle in the last 20 years. Materials and Methods: We carried out a review in the literature using PUBMED and Medline data bases. We analyzed 19 articles from the 4587 initially found, according to the inclusion and exclusion criteria. After the selection we analyzed the date of publishing and country of origin, sample size and type, dosage used, exercise protocol and results on skeletal muscle. Results: Most of the studies came from the USA, were published between the years of 2000 and 2005. Most of the papers used only males and the main dosage used was 3.0g/day with resistance exercise, although endurance exercise and untrained individuals showed some interesting results. Data from these studies varied from increase in muscle mass and muscle strength, recovery of isokinetic and isometric muscle function, decrease in lactate dehydrogenase and proteolysis and decrease in creatine kinase. Conclusion We can conclude that although HMβ has some positive effects on untrained individuals, its effects on trained individuals still need further conirmation.
Protective role of caffeine versus N-acetylcysteine in hyperoxic acute lung injury in neonatal rats
Authors: Sadek A. , Khattab R. , Amer A. , Youssef A. 
Published: July 2017

Abstract
Introduction: Prolonged breathing of high oxygen concentration leads to hyperoxic acute lung injury. Neonatal Respiratory diseases usually require increased supplement of high oxygen concentrations, so neonates are more susceptible to hyperoxic acute lung injury. The aim of this work was to investigate the protective role of caffeine versus N-acetylcysteine against hyperoxic acute lung injury in neonatal rats. Materials and Methods: 32 albino rats aged seven days were used in this experiment. The pups were divided into four groups; 1) Control or normoxic group; rats placed in normoxic chamber where fraction of inspired oxygen (FiO2) was 0.21, 2) Hyperoxic group; rats were placed in hyperoxic chamber (FiO2>0.8) using an oxygen flow of 1.5 Litre/min, 3) Hyperoxia-CAF group; rats exposed to hyperoxia and received a single intra-peritoneal injection of 20 mg/kg caffeine just prior to exposure, and 4) Hyperoxia-NAC group; rats exposed to hyperoxia and received a single intra-peritoneal injection of 150 mg/kg N-acetylcysteine just prior to exposure. 48 hours after exposure, lung specimens were processed for histological and immunohistochemical study using caspase-3, cluster of differentiation-68-antibody (CD68) and interleukin-1-beta (IL-1β). Results: Neonatal hyperoxia led to severe impairment in lung architecture, with a highly significant increase in alveolar macrophages. Also, caspase and IL-1β immune-reaction were increased significantly as compared to control group. Caffeine could improve the histolopathological picture of hyperoxic acute lung injury, and also could decrease alveolar macrophage count and IL-1β immune-reaction better than N-acetylcysteine. Conclusion: Caffeine is more effective than N-acetylcysteine in prophylaxis against hyperoxic acute lung injury in neonates.
“Climate response functions” for the Arctic Ocean: a proposed coordinated modelling experiment
Authors: Marshall John , Scott Jeffery , Proshutinsky Andrey 
Published: July 2017

Abstract. A coordinated set of Arctic modelling experiments, which explore how the Arctic responds to changes in external forcing, is proposed. Our goal is to compute and compare climate response functions (CRFs) – the transient response of key observable indicators such as sea-ice extent, freshwater content of the Beaufort Gyre, etc. – to abrupt step changes in forcing fields across a number of Arctic models. Changes in wind, freshwater sources, and inflows to the Arctic basin are considered. Convolutions of known or postulated time series of these forcing fields with their respective CRFs then yield the (linear) response of these observables. This allows the project to inform, and interface directly with, Arctic observations and observers and the climate change community. Here we outline the rationale behind such experiments and illustrate our approach in the context of a coarse-resolution model of the Arctic based on the MITgcm. We conclude by summarizing the expected benefits of such an activity and encourage other modelling groups to compute CRFs with their own models so that we might begin to document their robustness to model formulation, resolution, and parameterization.
Form and function in hillslope hydrology: in situ imaging and characterization of flow-relevant structures
Authors: Jackisch Conrad , Angermann Lisa , Allroggen Niklas , Sprenger Matthias , Blume Theresa , Tronicke Jens , Zehe Erwin 
Published: July 2017

Abstract. The study deals with the identification and characterization of rapid subsurface flow structures through pedo- and geo-physical measurements and irrigation experiments at the point, plot and hillslope scale. Our investigation of flow-relevant structures and hydrological responses refers to the general interplay of form and function, respectively. To obtain a holistic picture of the subsurface, a large set of different laboratory, exploratory and experimental methods was used at the different scales. For exploration these methods included drilled soil core profiles, in situ measurements of infiltration capacity and saturated hydraulic conductivity, and laboratory analyses of soil water retention and saturated hydraulic conductivity. The irrigation experiments at the plot scale were monitored through a combination of dye tracer, salt tracer, soil moisture dynamics, and 3-D time-lapse ground penetrating radar (GPR) methods. At the hillslope scale the subsurface was explored by a 3-D GPR survey. A natural storm event and an irrigation experiment were monitored by a dense network of soil moisture observations and a cascade of 2-D time-lapse GPR trenches. We show that the shift between activated and non-activated state of the flow paths is needed to distinguish structures from overall heterogeneity. Pedo-physical analyses of point-scale samples are the basis for sub-scale structure inference. At the plot and hillslope scale 3-D and 2-D time-lapse GPR applications are successfully employed as non-invasive means to image subsurface response patterns and to identify flow-relevant paths. Tracer recovery and soil water responses from irrigation experiments deliver a consistent estimate of response velocities. The combined observation of form and function under active conditions provides the means to localize and characterize the structures (this study) and the hydrological processes (companion study Angermann et al., 2017, this issue).
Prognostic factors for survival in metastatic renal cell carcinoma patients with brain metastases receiving targeted therapy
Authors: Yildiz Ibrahim , Bilici Ahmet , Karadurmuş Nuri , Ozer Leyla , Tural Deniz , Kaplan Mehmet A. , Akman Tülay , Bayoglu Ibrahim V. , Uysal Mükremin , Yildiz Yaşar , Tanriverdi Özgür , Yazici Ozan , Sürmeli Zeki , Serdar Turhal Nazim , Bavbek Sevil , Selçukbiricik Fatih , Koca Doğan , Basaran Mert 
Published: July 2017

Background: The primary objective of our study was to examine the clinical outcomes and prognosis of patients with metastatic renal cell carcinoma (mRCC) with brain metastases (BMs) receiving targeted therapy. Patients and methods: Fifty-eight patients from 16 oncology centers for whom complete clinical data were available were retrospectively reviewed. Results: The median age was 57 years (range 30-80). Most patients underwent a nephrectomy (n = 41; 70.7%), were male (n = 42; 72.4%) and had clear-cell (CC) RCC (n = 51; 87.9%). Patients were treated with first-line suni-tinib (n = 45; 77.6%) or pazopanib (n = 13; 22.4%). The median time from the initial RCC diagnosis to the diagnosis of BMs was 9 months. The median time from the first occurrence of metastasis to the development of BMs was 7 months. The median overall survival (OS) of mRCC patients with BMs was 13 months. Time from the initial diagnosis of systemic metastasis to the development of BMs (<12 months; p = 0.001), histological subtype (non-CC; p<0.05) and number of BMs (>2; p<0.05) were significantly associated with OS in multivariate analysis. There were no cases of toxic death. One mRCC patient with BMs (1.7%) experienced treatment-related cerebral necrosis. All other toxicities included those commonly observed with VEGF-TKI therapy. Conclusions: The time from the initial diagnosis of systemic metastasis to the development of BMs (<12 months), a non-CC histological subtype, and a greater number of BMs (>2) were independent risk factors for a poor prognosis.
Validation of Spectrophotometric Methods for the Determination of Total Polyphenol and Total Flavonoid Content
Authors: Matić Petra , Sabljić Marija , Jakobek Lidija 
Published: July 2017

Abstract
The aim of this study was to validate spectrophotometric methods for the measurement of total polyphenol (TP; via the Folin–Ciocalteu method) and total flavonoid (TF) content [via the aluminum chloride (AlCl3) method]. Validation parameters of these methods were determined, including linearity, sensitivity, precision (intra-assay and intermediate), accuracy, LOD, and LOQ. For the validation process, groups of polyphenol standards were used, including phenolic acids (gallic, p-coumaric, caffeic, and chlorogenic acids), flavan-3-ols [(+)-catechin and procyanidins B1 and B2], flavonols (quercetin and quercetin-3-rutinoside), and dihydrochalcones (phloretin and phloretin-2-glucoside). Obtained validation parameters were within acceptable ranges with high determination coefficients, reasonably low LODs and LOQs, and high slopes in the calibration curves for both methods, except for phloretin and phloretin-2-glucoside, for which there were low slopes in the calibration curves for the AlCl3 method. To evaluate differences in polyphenol content, the validated spectrophotometric methods were used to determine TP and TF content in wines (Plavac, Graševina, and Vranac) and juices (blueberry, strawberry, and blackcurrant juice) according to the polyphenol calibration curves. Polyphenol contents were different for both methods in all wines and juices.
The genus Diplommatina Benson, 1849 (Gastropoda: Caenogastropoda: Diplommatinidae) in Nepal, with the description of seven new species
Authors: Budha Prem B. , Naggs Fred , Backeljau Thierry 
Published: July 2017

This paper deals with the taxonomy and faunistics of the genus Diplommatina in Nepal. Altogether 16 species are reported, seven of which are new to science viz. D. abiesiana sp. nov., D. fistulata sp. nov., D. godawariensis sp. nov., D. maipokhariensis sp. nov., D. salgharica sp. nov., D. shivapuriensis sp. nov. and D. syabrubesiensis sp. nov. Information on nine previously reported species is provided: D. exserta Godwin-Austen, 1886, D. folliculus (L. Pfeiffer, 1846), D. miriensis Godwin-Austen, 1917, D. munipurensis Godwin-Austen, 1892, D. oviformis Fulton, 1901, D. pachycheilus Benson, 1857, D. regularis Fulton, 1901, D. silvicola Godwin-Austen, 1886 and D. sperata W.T. Blanford, 1862. Although D. canarica was once reported from Nepal, it is not treated here as it is an endemic of the Western Ghats. A dichotomous identification key for all Nepalese species is presented.
Apoio social ao doente oncológico com base na escala do Medical Outcomes Study
Authors: Portalupi da Trindade Clediane Rita , Hahn Giselda Veronice 
Published: July 2017

Objetivo: mensurar o apoio social disponível aos doentes oncológicos e verificar se os resultados apresentam diferença entre os sexos. Método: estudo quantitativo, do tipo transversal. Para a coleta e análise dos dados utilizou-se a escala do Medical Outcomes Study. Foram entrevistados 80 participantes de ambos os sexos. Os dados foram submetidos à análise estatística. Resultados: os homens manifestaram ter maior apoio material e emocional, acesso à informação e interação social positiva. Entre as mulheres somente a manifestação de Apoio Afetivo apresentou maior destaque. A falta de companheiro e o surgimento do câncer em mulheres mais jovens foram fatores que reduziram o nível de apoio social. Conclusão: a maioria dos participantes revelou ter apoio social disponível, o que permite avaliar que esses indivíduos suprem suas necessidades básicas de apoio. Considera-se importante os profissionais da saúde estarem atentos às necessidades de apoio manifestadas pelas mulheres, pois estas apresentaram menor disponibilidade de apoio.
Secondary gravity wave generation over New Zealand during the DEEPWAVE campaign
Authors: Bossert Katrina , Kruse Christopher G. , Heale Christopher J. , Fritts David C. , Williams Bifford P. , Snively Jonathan B. , Pautet Pierre‐Dominique , Taylor Michael J. 
Published: July 2017

AbstractMultiple events during the Deep Propagating Gravity Wave Experiment measurement program revealed mountain wave (MW) breaking at multiple altitudes over the Southern Island of New Zealand. These events were measured during several research flights from the National Science Foundation/National Center for Atmospheric Research Gulfstream V aircraft, utilizing a Rayleigh lidar, an Na lidar, and an Advanced Mesospheric Temperature Mapper simultaneously. A flight on 29 June 2014 observed MWs with horizontal wavelengths of ~80–120 km breaking in the stratosphere from ~10 to 50 km altitude. A flight on 13 July 2014 observed a horizontal wavelength of ~200–240 km MW extending from 20 to 90 km in altitude before breaking. Data from these flights show evidence for secondary gravity wave (SGW) generation near the breaking regions. The horizontal wavelengths of these SGWs are smaller than those of the breaking MWs, indicating a nonlinear generation mechanism. These observations reveal some of the complexities associated with MW breaking and the implications this can have on momentum fluxes accompanying SGWs over MW breaking regions.
Anthropogenic pollution elevates the peak height of new particle formation from planetary boundary layer to lower free troposphere
Authors: Quan Jiannong , Liu Yangang , Liu Quan , Jia Xingcan , Li Xia , Gao Yang , Ding Deping , Li Jie , Wang Zifa 
Published: July 2017

AbstractNew particle formation (NPF) and subsequent growth are primary sources of atmospheric aerosol particles and cloud condensation nuclei. Previous studies have been conducted in relatively clean environments; investigation of NPF events over highly polluted megacities is still lacking. Here we show, based on a recent yearlong aircraft campaign conducted over Beijing, China, from April 2011 to June 2012, that NPF occurrence peaks in the lower free troposphere (LT), instead of planetary boundary layer (PBL), as most previous studies have found and that the distance of NPF peak to PBL top increases with increasing aerosol loading. Further analysis reveals that increased aerosols suppress NPF in PBL, but enhance NPF in LT due to a complex chain of aerosol‐radiation‐photochemistry interactions that affect both NPF sources and sinks. These findings shed new light on our understanding of NPF occurrence, NPF vertical distribution, and thus their effects on atmospheric photochemistry, clouds, and climate.
Seismic velocity structure in the source region of the 2016 Kumamoto earthquake sequence, Japan
Authors: Shito Azusa , Matsumoto Satoshi , Shimizu Hiroshi , Ohkura Takahiro , Takahashi Hiroaki , Sakai Shinichi , Okada Tomomi , Miyamachi Hiroki , Kosuga Masahiro , Maeda Yuta , Yoshimi Masayuki , Asano Youichi , Okubo Makoto 
Published: July 2017

AbstractWe investigate seismic wave velocity structure and spatial distribution of the seismicity in the source region of the 2016 Kumamoto earthquake sequence. A one‐dimensional mean velocity shows that the seismogenic zone has a high‐velocity and low‐Vp/Vs ratio relative to the average velocity structure of Kyushu Island. This indicates that the crust is relatively strong, capable of sustaining sufficiently high strain energy to facilitate two large (Mj > 6.5) earthquakes in close proximity to one another in rapid succession. Three‐dimensional tomography of the seismogenic zone around the source of the 2016 Kumamoto earthquake sequence yields Vp = 6 km/s and Vs = 3.5 km/s. Most large‐displacement areas (asperities) of the Mj 7.3 event overlap with the seismogenic zone and the overlying surface layer. Aftershock seismicity is distributed deeper than the conventional seismogenic zone, which suggests decreased strength due to fluids or increased stress, both caused by coseismic slip.
Observation and simulation of the ionosphere disturbance waves triggered by rocket exhausts
Authors: Lin Charles C. H. , Chen Chia‐Hung , Matsumura Mitsuru , Lin Jia‐Ting , Kakinami Yoshihiro 
Published: July 2017

AbstractObservations and theoretical modeling of the ionospheric disturbance waves generated by rocket launches are investigated. During the rocket passage, time rate change of total electron content (rTEC) enhancement with the V‐shape shock wave signature is commonly observed, followed by acoustic wave disturbances and region of negative rTEC centered along the trajectory. Ten to fifteen min after the rocket passage, delayed disturbance waves appeared and propagated along direction normal to the V‐shape wavefronts. These observation features appeared most prominently in the 2016 North Korea rocket launch showing a very distinct V‐shape rTEC enhancement over enormous areas along the southeast flight trajectory despite that it was also appeared in the 2009 North Korea rocket launch with the eastward flight trajectory. Numerical simulations using the physical‐based nonlinear and nonhydrostatic coupled model of neutral atmosphere and ionosphere reproduce promised results in qualitative agreement with the characteristics of ionospheric disturbance waves observed in the 2009 event by considering the released energy of the rocket exhaust as the disturbance source. Simulations reproduce the shock wave signature of electron density enhancement, acoustic wave disturbances, the electron density depletion due to the rocket‐induced pressure bulge, and the delayed disturbance waves. The pressure bulge results in outward neutral wind flows carrying neutrals and plasma away from it and leading to electron density depletions. Simulations further show, for the first time, that the delayed disturbance waves are produced by the surface reflection of the earlier arrival acoustic wave disturbances.