bluuebunny/crossref_metadata_2025_split huggingface dataset:
The The Influence of Perceived Waiting Time, AI Utilization, and Medication Information Delivery on Word of Mouth: A Qualitative Preliminary Study at Hospital Balikpapan
Authors: Rozet Stefly J. A. , Yusriani Sri , Sitompul Rustina , Supriyanto Edi , Jasmine Khanza , Utomo Kabul Wahyu 
Published: October 2024

Abstract:
There is currently a lack of comprehensive, intuitive, and usable formative evaluation frameworks to improve word of mouth (WOM) at our hospital. Therefore, we aimed to develop and apply such a framework through a literature review analysis. This preliminary study seeks to analyze the influence of perceived waiting time, AI utilization, and medication information delivery on WOM at Hospital Balikpapan through a qualitative approach. Using a literature review method, we examined 20 relevant studies to understand the relationships between waiting time, AI utilization, medication information, patient satisfaction, and WOM. The findings suggest that patient satisfaction plays a crucial role in mediating the effects of waiting time, AI utilization, and medication information on WOM. Additionally, AI-based tools can help reduce waiting times by optimizing scheduling and resource allocation, and improve medication information delivery through AI-led chatbot services, providing accurate and timely drug information to patients. This study highlights the importance of addressing patient expectations and improving communication in pharmaceutical services to enhance patient satisfaction and positive WOM. Furthermore, the acceptance and utilization of AI in healthcare can significantly contribute to better patient experiences. Our review underscores the need for continuous improvement in service delivery and the potential benefits of integrating AI technologies in hospital settings. By focusing on these areas, hospitals can enhance patient satisfaction, leading to increased positive WOM and overall better healthcare outcomes.

Keywords: Perceived waiting time, AI utilization, medication information delivery, patient satisfaction, word of mouth, qualitative study, hospital.
Analysis of Service Excellent at PT Home Tester Indonesia
Authors: Amanda Julia Zahra  
Published: October 2024

Service Excellent is an activity carried out by a service provider with the specific aim of providing satisfaction that can be felt by customers. Services must be connected to consumers' hopes and desires for the products or services offered by a company so that consumers feel satisfaction This Research is executed to find out the applied service excellent that is used by PT. Home Tester Indonesia. The methode of research used is qualitative descriptive that gives the portrayal of service excellent of PT. Home Tester Indonesia. Data collection techniques arecarried out through, namely observation, interviews, and documentation. the result of this research shows the excellent service that is done by PT. Home Tester Indonesia is good based on the attitudes, abilities, attention, actions, and responsibilities performed by the employees of the PT. Home Tester Indonesia. However, those are considered not optimal as the employees performed delayed response in serving the community.
Equisetum diffusummethanol extract attenuates RA by modulating the expression of key biomarkers like COX-2, TNF-α, IL-6, PPAR-γ, and Iκβ in Adjuvant-induced rats.
Authors: Sarkar Sourav , Modak Debabrata , Roy Sudipta Kumar , Ashraf Gouhar Jahan , Chakrabarty Ayan , Sahu Ranabir , Bhattacharjee Soumen 
Published: October 2024

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with subsequent damage to the bone joints. Equisetum diffusum D. Don, from the Equisetaceaefamily, is a native pteridophyte species of the sub-Himalayan region of India and has been reported to have a diverse array of pharmacological properties. The present research is focused on determining the anti-arthritic potential of E. diffusum whole plant methanol extract (EDME) in adjuvant-induced arthritic rats. Treatment with EDME significantly restored paw-edema, arthritic scoring, and normal body weight. EDME treatment also normalized the haematological, biochemical, radiological, and histological status when compared to the arthritic control rats. The methanol extract significantly (p<0.05) attenuated arthritis progression by downregulating the gene expression of pro-inflammatory mediators, like COX-2, TNF-α, IL-6, and upregulating the expression of anti-inflammatory mediators PPAR-γ, Iκβ in a dose-dependent manner. Significantly, EDME also reduced the serum concentration of COX-2, TNF-α, and IL-6 compared to arthritic control rats (p<0.05). The treatment with EDME also normalized the oxidative stress level in liver by restoring the GSH level, CAT and SOD activities and reducing the elevated MDA level. HPTLC and LC-MS/MS analyses of EDME confirmed the presence of potent polyphenols (chlorogenic acid, 4-hydroxycinnamic acid) and flavonoids (kaempferol), thereby suggesting the anti-arthritic property of the plant. All our findings established the anti-arthritic potential of E. diffusumextract in chronic arthritis model on a strong ground.
Optimized simple culture protocol for inducing mature myotubes from MYOD1-overexpressed human iPS cells
Authors: Wada Eiji , Susumu Nao , Okuzaki Yuya , Hotta Akitsu , Sakurai Hidetoshi , Hayashi Yukiko 
Published: October 2024

Abstract

The forced expression system of MYOD1, a master gene for myogenic differentiation, can efficiently and rapidly reproduce muscle differentiation of human induced pluripotent stem cells (hiPSCs). Despite these advantages of the MYOD1 overexpression system, developed myotubes are relatively immature and do not recapitulate several aspects of striated muscle fibers. Here, we developed a simple optimized protocol using an alternative culture medium for maximizing the advantages of the MYOD1 overexpression system, and successfully improved the formation of multinucleated mature myotubes within 10 days. In this study, we generated hiPSCs derived from healthy donors and an individual with congenial muscular dystrophy caused by LMNA mutation (laminopathy), and compared disease-associated phenotypes in differentiated myotubes generated by the conventional method and by our new optimized culture method. Using our optimized method, abnormal myonuclear shape was pronounced in the patient-derived iPSCs. In addition, abnormal accumulation of the nuclear membrane protein emerin was observed in LMNA-mutant hiPSCs. Our new culture method is expected to be widely applicable as a MYOD1 overexpression model of hiPSC-derived skeletal muscle cells for the analysis of a variety of muscle diseases.
Ghrelin ameliorates cognitive deficits and restores dopamine responses to external stimuli in the PFC via D1 receptor signaling in Mecp2 KO mice, a mouse model for Rett syndrome
Authors: Kawahara Yukie , Ohnishi Yoshinori , Takahashi Tomoyuki , Kishikawa Yuki , Yuge Kotaro , Kawahara Hiroshi , Yamashita Yushiro , Matsuishi Toyojiro , Nishi Akinori 
Published: October 2024

Abstract

Rett syndrome is an X-linked neurodevelopmental disorder characterized by cognitive impairments along with sensory and motor deficits. Ghrelin is known to improve cognitive function in various animal models with cognitive deficits. Optimum activation of dopamine D1 receptor signaling in the prefrontal cortex (PFC) plays a critical role in cognitive performance. In this study, we investigated the effects of ghrelin on cognitive function and D1 receptor-mediated dopamine neurotransmission in the PFC of Mecp2 knockout (KO) mice, a mouse model for Rett syndrome. In the modified novel object recognition test, cognitive function was impaired in Mecp2 KO mice, and ghrelin injection (8.6 µg/mouse, s.c.) improved the cognition of objects and investigatory behaviors. In in vivo microdialysis studies, external stimuli such as saline injection and novelty induced increases in dopamine levels in the PFC of wild-type mice, and the dopamine release was bidirectionally regulated by D1 receptors. In the PFC of Mecp2 KO mice, the dopamine responses to external stimuli were attenuated and the dopamine reuptake system was upregulated. Pharmacological analyses revealed that the ability of D1 receptor signaling to inhibit dopamine release would be upregulated and/or its ability to stimulate dopamine release would be downregulated in Mecp2 KO mice. Ghrelin injection restored dopamine responses to external stimuli by adjusting the altered function of D1 receptor signaling. These results suggest that the ability of ghrelin to restore dopamine neurotransmission via D1 receptor-mediated mechanisms likely contributes to its therapeutic effects on cognitive deficits in Mecp2 KO mice.
Green synthesis of zeolite and its regeneration for adsorption of ammonia nitrogen in water
Authors: Cheng Jie , Liu Junjie , Zhang Ze , Wang Jing , Bi Shiming , Tang Xiaojun , Huang Zhujian 
Published: October 2024

Abstract

This study presents a novel green approach for the preparation of zeolite material from fly ash using a combination of mechanochemical method. Compared to traditional methods, this approach reduces energy consumption, minimizes reagent usage, and facilitates the efficient recycling of fly ash. The physicochemical properties of the synthesized zeolite, including crystal structure and porosity, were systematically investigated. The synthesized zeolite was employed for the adsorption of ammonia nitrogen from aqueous solutions, and their adsorption kinetics and thermodynamics were comprehensively studied. The results revealed that the adsorption of ammonia nitrogen onto the zeolite follows the Langmuir adsorption model. Additionally, the zeolite exhibited strong selective adsorption and remarkable resistance to interference from coexisting cations in the aqueous solution. Finally, regeneration experiments were conducted using NaCl, NaClO, and their mixtures to desorb ammonia nitrogen from the spent zeolite. A total of 17 regeneration cycles were performed until the adsorption capacity of the zeolites was exhausted. The adsorption performance of the regenerated zeolite was evaluated to assess the impact of different reagents and regeneration cycles on adsorption efficiency. The optimal regeneration method was identified, leading to the successful valorization of fly ash into zeolite for ammonia adsorption and the development of effective regeneration strategies for spent zeolite.
Long-Term Real-Life Outcomes of Vitrectomy and Air Tamponade for Primary Retinal Detachment Repair
Authors: Mete Maurizio , Maggio Emilia , Prigione Guido , Bruni Enrico , Maraone Giorgia , Tripodi Sarah , Santis Nicoletta , Guerriero Massimo , Pertile Grazia 
Published: October 2024

Abstract

Purpose
To report outcomes of pars plana vitrectomy (PPV) with air tamponade for primary rhegmatogenous retinal detachment (RRD) and investigate the impact of vitreous cortex remnants (VCR) on surgical outcomes.
Methods
A retrospective review of 900 patients treated for uncomplicated primary RRD between 2007 and 2020. Exclusion criteria included axial length > 26 mm, prior retinal surgery, giant retinal tear, PVR grade > B, and inadequate follow-up. Primary outcomes were retinal reattachment rate and best-corrected visual acuity (BCVA).
Results
Of 900 patients, 397 met inclusion criteria. Primary reattachment rate was 88.4%, with significant BCVA improvement. Forty-six eyes experienced RRD recurrence. Complications included cataracts (38.8%), IOP rise (11.4%), and macular edema (8.3%). Better final BCVA was associated with preoperative macular non-involvement and absence of reinterventions. No significant association was found between RRD recurrence and various factors, including VCR removal.
Conclusion
Air tamponade is a safe and effective option for primary RRD treatment. It has no negative effect on the environment and creates less discomfort for patients. VCR removal did not significantly reduce RRD recurrence in the overall number of cases. Further research will help determine the role of VCR in RD recurrence and define in which cases their removal might be beneficial.
Inhibition or promotion? The effects of executive power on R&amp;D investment
Authors: Zuo Xuelian , Luo Shiwen , Zhou Ting 
Published: October 2024

Abstract

This study explored executive power’s influence on corporate R&D investment based on social psychology theory. It also examined the impact of media attention and institutional environment on the relationship between executive power and enterprise R&D investment as an external governance mechanism. Empirical verification was carried out using data on listed companies on China's small and medium-sized board and growth enterprise market from 2013 to 2018. The results show a significant positive correlation between executive power and corporate R&D investment. Further research reveals that ownership power, organizational power, and reputational power significantly promote enterprises’ R&D investments. Expert power has no significant impact on R&D investment. In enterprises with lower media attention, the influence of executive power on R&D investment is more significant. In enterprises with a poorer institutional environment, the influence of executive power on R&D investment is more significant.
Post-traumatic growth experiences of parents of children with congenital deafness: a qualitative study
Authors: Wu Ting , Zhu Chencheng , Zhang Chunjing , Liu Pei , Cui Yuanyuan , Zhang Biaoxin 
Published: October 2024

Abstract

Background
Hearing disability is the most common of the five major disabilities in China, and hearing disability seriously affects human health and quality of life. A child's diagnosis of deafness is an intensely traumatic event for parents, who have to bear multiple pressures and burdens in the process of caring for their child. However, it is crucial for parents to draw good meanings from the traumatic incident and to create new insights into life, which is important for their own physical and mental health and that of their child.
Methods
Using purposive sampling, 15 parents of congenitally deaf children admitted to the Department of Otolaryngology, Head and Neck Surgery of a tertiary-level hospital in Hefei City from April to July 2023 were selected for semi-structured interviews, and Colaizzi's seven-step analysis method was applied to analyze the data and refine the themes.
Results
Six main themes and fourteen sub-themes were summarized in this study: (1) changes in outlook on life, (2) enhancement of health concepts, (3) increased personal strength, (4) change in relationships with others, (5) perceived social support, and (6) positive coping styles.
Conclusion
Parents of children with congenital deafness can experience multifaceted growth in the process of caregiving. Medical staff should pay full attention to the psychological experience of parents of children with congenital deafness, explore their strengths and potentials, increase the degree of social support, and promote coping positively with the level of post-traumatic growth, to enhance the quality of care and the rehabilitation effect of the children.
Impulsivity and Antisocial Behavior in Sports: The Moderating Role of Self-Control
Authors: Lu Congsheng , Shi Bing 
Published: October 2024

Abstract

Impulsivity, often defined as the propensity to act hastily without thoroughly weighing the consequences, is a recognized contributor to antisocial behavior. However, the mechanisms that might mitigate the influence of impulsivity on antisocial tendencies remain unclear. Across two studies, we tested the proposition that self-control moderates this relationship, such that high levels of self-control diminish the connection between impulsivity and antisocial behavior. Study 1, a cross-sectional analysis with 225 professional basketball players, and Study 2, a six-month longitudinal study with 349 professional athletes from various sports, provided evidence supporting this hypothesis. Specifically, the link between impulsivity and antisocial behavior was either negligible (Study 1) or significantly reduced (Study 2) in the presence of stronger self-control. The findings suggest the value of integrating self-control techniques in physical activity contexts to potentially curb antisocial behavior.
Gut microbiota, lipids, immunity, and liver disease: Insights from Mendelian Randomization and murine models
Authors: Lei Langhuan , lin jiali , liang qiuyu , huang xiaozhi , yang xing , shi wei , pan liuxian , li wei , Yang Jianrong 
Published: October 2024

Abstract

Liver diseases, including NAFLD and cirrhosis, are significant health issues. This study used Mendelian Randomization (MR) to identify causal links between gut microbiota, lipidomes, immunophenotypes, inflammatory factors, and liver diseases, while also evaluating the therapeutic potential of Lactobacillus salivarius in NAFLD murine models. Summary statistics from GWAS for gut microbiota traits, lipidome components, immune cell counts, inflammatory cytokines, and liver disease traits were analyzed. MR analysis identified causal relationships, with sensitivity analyses confirming the results. Notable findings included 53 gut microbiota taxa, 28 lipidome components, 92 immune cell types, and 8 cytokines linked to liver diseases. Key taxa like Megamonas funiformis increased liver disease risk, while phosphatidylcholines (PCs) were protective. Immune markers such as CD33 on CD33dim HLA-DR- correlated with higher risk, while CD3 on CD39 + resting Tregs and LIF/LIF-R were protective. In vivo, Lactobacillus salivarius treatment significantly improved metabolic and hepatic parameters. The study emphasizes the causal role of gut microbiota and related factors in liver diseases and highlights Lactobacillus salivarius as a promising therapeutic option for NAFLD.
The Mechanistical Principles and Engineering Application of Top- Cutting for Roadway Protection in Advance of the Working Face
Authors: Li Zhaotai , Zhou Yuejin , Xu Xiaoding , Xiao Yuhang , Xu Yunong 
Published: October 2024

Abstract

In coal mining operations, it is often challenging to control the deformation of the roadway in front of the working face. The excessive stress from the surrounding rock of the working face and the difficulties in caving the goaf roof have led to a prominent factor that hinders safe and efficient production in coal mines. For this reason, a mechanical model of the stress field in the advance roadway of the working face is established, and the stress evolution law of the surrounding rock before and after cutting the roof of the roadway is analyzed. Key parameters such as cutting depth, cutting angle, and hole spacing are determined through theoretical calculation, numerical simulation with 3DEC numerical software, and field testing. A kind of roof cutting and pressure relief techniques (TCPAF) for enhanced roadway safeguarding in advance mining face is proposed, and its effectiveness is verified through field testing. The results indicate that the stress on the low-stress side of the leading roadway remains slightly increased, while on the high-stress side, stress decreases significantly,optimizing the stress environment of the surrounding rock. In addition, the research results provide a scientific basis for similar conditions of roadway deformation.
Mechanism of anti-reflective crack extension of glass fiber grating validated through finite element simulation
Authors: Bai Wenjun 
Published: October 2024

Abstract

In highway maintenance, asphalt overlays are commonly employed to enhance the performance of aging asphalt pavements. Over time, joints and cracks in the old pavement, particularly those involving horizontal displacement, tend to propagate as reflection cracks. Fiberglass grids are extensively used to mitigate or prevent these reflective cracks due to their beneficial properties. However, existing indoor evaluation methods for reflection cracks face several limitations, including large specimen geometries, poor operability, significant variability in fatigue test results, and inadequate simulation of real traffic conditions with monotonous loading and single-indicator evaluations. To address these issues, this study designed a new test method for evaluating the anti-reflective cracking performance of fiberglass grating. The developed method aimed to rationally select appropriate fiberglass grating and elucidate the reflective crack propagation process in the cover layer. A novel index, termed the “destruction rate,” was introduced to assess the performance of fiberglass grating against reflective cracking. The study investigated the role of fiberglass grating in crack propagation and the underlying mechanisms. The Superpave rotary compaction method was employed to measure the volumetric parameters of the mixture, while indirect tensile strength, resilience modulus, and creep tests were conducted to determine the mixture's basic parameters. Composite specimens, with a maximum dimension of 150 mm, were evaluated using the new index “destruction rate” to characterize the performance of fiberglass grating during fatigue tests. The crack expansion mechanism was analyzed using HMA fracture mechanics and subsequently simulated and validated using ABAQUS finite element software. The results indicated that the destruction rate effectively characterized the anti-reflective crack performance of fiberglass grating and that composite specimens helped reduce variability in fatigue test results. This approach provided valuable support for evaluating grating performance and conducting theoretical research. HMA fracture mechanics calculations revealed that the destruction of the grating preceded that of the asphalt overlay layer, with reliable predictions of anti-reflective crack performance confirmed through ABAQUS finite element simulations.
Conservation agriculture enhances maize yields and profitability in Mexico's semi-arid highlands
Authors: Saldivia-Tejeda Abel , Uribe-Guerrero Miguel Ángel , Rojas-Cruz Juan Manuel , Guera Ouorou Ganni Mariel , Verhulst Nele , Fonteyne Simon 
Published: October 2024

Abstract

Rainfed agriculture in semi-arid regions is affected by variable rainfall patterns, resulting in low yields under conventional farming systems. To address this issue, cropping systems based on conservation agriculture were evaluated in 2 field experiments on 17 farmers' fields in the semi-arid highlands of Queretaro, Mexico, from 2013 to 2020, to assess yields and profitability. Monocropped maize (Zea mays L.) under conventional tillage was compared to growing maize on permanent beds with soil mulch, either monocropped or in rotation with triticale (X Triticum Secale Wittmack), oats (Avena sativa L.), or common beans (Phaseolus vulgaris L.). In the San Juan del Rio field experiment, maize yields on permanent beds averaged from 2,475 to 3,517 kg ha− 1 over five years, exceeding 70% the yields under conventional tillage.. In the Cadereyta field experiment, 4-year average maize yields on permanent beds ranged from 979 to 1,382 kg ha− 1 with no significant difference to those under conventional tillage. In farmers' fields, maize on permanent beds yielded an average of 3,717 kg ha− 1, 70% higher than with conventional tillage. The most profitable system was permanent beds with a maize-bean rotation in field experiments and with maize monocropping in farmers' fields. Overall, conservation agriculture can improve maize yields and profitability in Central Mexico's semi-arid highlands.