bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the wing density and the inflation factor of aircraft
Authors: Huyssen R. J. , Mathews E. H. , Liebenberg L. , Spedding G. R. 
Published: February 2016

ABSTRACTThe aviation industry is dominated by the domain of heavier-than-air, fixed-wing, subsonic flight, and central to any design in this domain is the wing itself. One of the earliest debates in aviation still centres around the usefulness of the wing volume. On the one hand it is held that the wing, as an inevitable necessity, should provide the volume also for the payload. On the other, it is argued that more efficient wings do not even have sufficient volume for the entire wing structure. This work proposes precise definitions of theWing Densityand theInflation Factor, two parameters that can quantitatively reflect the economic and technological trends in aviation. The wing volume of a hypotheticalIdeal Wingis derived from theOperational Parametersof any givenFlight Objectiveand compared to the volume requirement of that flight objective. We conclude that the dominant aircraft configuration of the future is likely to remain within the same family of the current dominant configuration, in conflict with some older predictions.
The Feasibility of an Infection Control “Safe Zone” in a Spinal Cord Injury Unit
Authors: Lones Keshonna , Ramanathan Swetha , Fitzpatrick Margaret , Hill Jennifer N. , Guihan Marylou , Richardson Michael S. A. , Evans Charlesnika T. 
Published: February 2016

We report on healthcare worker use of a safe zone (outside a 3-foot perimeter around the patient’s bed) and personal protective equipment in 2 inpatient spinal cord injury/disorder units. Workers remained within the safe zone during 22% of observations but were less compliant with personal protective equipment inside the zone.Infect Control Hosp Epidemiol 2016;37:714–716
Juxtaposing Constitution-Making and Constitutional-Infringement Mechanisms in Israel and Canada: On the Interplay between Common Law Override and Sunset Override
Authors: Weill Rivka 
Published: February 2016

This article explores the often neglected relationships between constitution-making (including amendment) mechanisms and constitutional-infringement mechanisms by focusing on the override as one of the possible tools to depart from a Constitution. The article suggests that there are two types of override: a ‘common law override’, which is not uniquely Canadian, and a ‘sunset override’. The common law override evolves in the judicial decisions of a given country when the courts require the legislature to explicitly take responsibility for an action. Under the common law override, we may couple together phenomena that are not typically connected, including a means of protecting common law rights, a judicial presumption against delegation of power to administrative agencies, and mechanisms of dealing with procedural or substantive legislative entrenchment. In contrast, the sunset override is a Canadian invention. For the tool to be part of the infringement mechanisms of a country's Constitution, it must be provided for explicitly in that Constitution, and its exercise must be temporary.This article follows the various possible uses of the common law override. It shows that Israel has vast experience with the common law override which may shed light on Israel's future possible exploitation of the sunset override. The article then shows that Israel has adopted the sunset override following the Canadian example. When the Rabin government adopted the tool as part of an exchange deal with the ultra-orthodox religious political party Shas, the terms of the deal included Shas' acquiescence to the peace process in exchange for the Rabin government's use of the override to protect the religious status quo from judicial intervention. In addition, the Israeli justices played an active and unique role in the birth and formulation of the Israeli override. As has happened with the Canadian override, supposedly these circumstances should have made the override illegitimate in Israel. However, this article argues that it is not the political uses of the override that result in its lack of use. Rather, the determining factor is the override's compatibility with the constitution-making process in a given country. From a normative perspective, it is easier for the Israeli legislature to override its own earlier enactments, even those titled Basic Laws, than it is for the Canadian legislature to override the People's enactment of the Charter. Thus, it is expected that Israel might more freely deploy the sunset override were it to become a general mechanism embodied in the Basic Laws, while, in contrast, the sunset override has fallen into disuse in Canada.
Effects of Age of English Exposure, Current Input/Output, and grade on bilingual language performance
Authors: BEDORE LISA M. , PEÑA ELIZABETH D. , GRIFFIN ZENZI M. , HIXON J. GREGORY 
Published: February 2016

AbstractThis study evaluates the effects of Age of Exposure to English (AoEE) and Current Input/Output on language performance in a cross-sectional sample of Spanish–English bilingual children. First- (N= 586) and third-graders (N= 298) who spanned a wide range of bilingual language experience participated. Parents and teachers provided information about English and Spanish language use. Short tests of semantic and morphosyntactic development in Spanish and English were used to quantify children's knowledge of each language. There were significant interactions between AoEE and Current Input/Output for children at third grade in English and in both grades for Spanish. In English, the relationship between AoEE and language scores were linear for first- and third-graders. In Spanish a nonlinear relationship was observed. We discuss how much of the variance was accounted for by AoEE and Current Input/Output.
Weekend Pottery Workshop at White Gum Valley Special School
Authors: Davies Marion J. 
Published: February 2016

Unless there is a specialist art and craft teacher in the school, this area of instruction is left to the classroom teacher. Such was the case at White Gum Valley. As my special interest is pottery, I use this medium for craft lessons. Many students from other classes expressed the desire to take pottery, so I decided to hold a weekend workshop for them.The general aims were to consolidate expressed interest in a rewarding leisure time activity, to help develop mature attitudes, good work habits and responsibility. I also hoped to foster perseverance, care and attention to detail, to increase concentration span and to develop a critical appraisal of one’s work.
Scientists, Career Choices and Organisational Change: Managing Human Resources in Cross Sector R&D Organisations
Authors: Turpin Tim , Garrett-Jones Sam , Diment Kieren 
Published: February 2016

ABSTRACTThe resource-based view of the firm has drawn attention to the role of human resources in building innovative capacity within firms. In ‘high technology’ firms, scientific capability is a critical factor in achieving international competitiveness. Science, however, is a costly business and many firms are entering into cross-sector R&D partnerships in order to gain access to leading edge scientific capability. The Australian Cooperative Research Centres (CRC) program is typical of the ways many governments are seeking to promote such cross-sector R&D collaboration. Scientists are key resources in these organisational arrangements. However, there is only fragmentary information available about why and when scientists choose to work in these cross-sector organisations rather than others, or the impact of changing funding regimes on their career choices. Similarly, there has been little research into the impact of such partnerships and career choices on the organisations in which scientists work. This paper presents some findings from two new ARC funded studies in Australia designed to investigate the careers of scientists and the organisational and career implications of participation in cross-sector R&D collaboration. One of our findings is that CRCs may not endure as long term ‘hybrid’ organisational arrangements as some observers have suggested, but rather remain as transitional structure influencing the partners involved and the careers of scientists. This has important implications for the managers of CRCs as well as those responsible for partner organisations.
On-chip photonic Fourier transform with surface plasmon polaritons
Authors: Kou Shan Shan , Yuan Guanghui , Wang Qian , Du Luping , Balaur Eugeniu , Zhang Daohua , Tang Dingyuan , Abbey Brian , Yuan Xiao-Cong , Lin Jiao 
Published: February 2016

AbstractThe Fourier transform (FT), a cornerstone of optical processing, enables rapid evaluation of fundamental mathematical operations, such as derivatives and integrals. Conventionally, a converging lens performs an optical FT in free space when light passes through it. The speed of the transformation is limited by the thickness and the focal length of the lens. By using the wave nature of surface plasmon polaritons (SPPs), here we demonstrate that the FT can be implemented in a planar configuration with a minimal propagation distance of around 10 μm, resulting in an increase of speed by four to five orders of magnitude. The photonic FT was tested by synthesizing intricate SPP waves with their Fourier components. The reduced dimensionality in the minuscule device allows the future development of an ultrafast on-chip photonic information processing platform for large-scale optical computing.
Weight loss is associated with plasma free amino acid alterations in subjects with metabolic syndrome
Authors: Tochikubo O , Nakamura H , Jinzu H , Nagao K , Yoshida H , Kageyama N , Miyano H 
Published: February 2016

Abstract
Objectives:
The prevalence of metabolic syndrome is increasing worldwide, especially in Asian populations. Early detection and effective intervention are vital. Plasma free amino acid profile is a potential biomarker for the early detection for lifestyle-related diseases. However, little is known about whether the altered plasma free amino acid profiles in subjects with metabolic syndrome are related to the effectiveness of dietary and exercise interventions.

Methods:
Eighty-five Japanese subjects who fulfilled the Japanese diagnostic criteria for metabolic syndrome were enrolled in a 3-month diet and exercise intervention. The plasma free amino acid concentrations and metabolic variables were measured, and the relationships between plasma free amino acid profiles, metabolic variables and the extent of body weight reduction were investigated. Those who lost more than 3% of body weight were compared with those who lost less than 3%.

Results:
Baseline levels of most amino acids in the subset that went on to lose <3% body weight were markedly lower compared with the counterpart, although both groups showed similar proportional pattern of plasma amino acid profiles. The weight loss induced by the diet and exercise intervention normalized plasma free amino acid profiles. For those with a high degree of weight loss, those changes were also associated with improvement in blood pressure, triglyceride and hemoglobin A1c levels.

Conclusions:
These data suggest that among Japanese adults meeting the criteria for metabolic syndrome, baseline plasma free amino acid profiles may differ in ways that predict who will be more vs less beneficially responsive to a standard diet and exercise program. Plasma free amino acid profiles may also be useful as markers for monitoring the risks of developing lifestyle-related diseases and measuring improvement in physiological states.
Singularity of the time-energy uncertainty in adiabatic perturbation and cycloids on a Bloch sphere
Authors: Oh Sangchul , Hu Xuedong , Nori Franco , Kais Sabre 
Published: February 2016

AbstractAdiabatic perturbation is shown to be singular from the exact solution of a spin-1/2 particle in a uniformly rotating magnetic field. Due to a non-adiabatic effect, its quantum trajectory on a Bloch sphere is a cycloid traced by a circle rolling along an adiabatic path. As the magnetic field rotates more and more slowly, the time-energy uncertainty, proportional to the length of the quantum trajectory, calculated by the exact solution is entirely different from the one obtained by the adiabatic path traced by the instantaneous eigenstate. However, the non-adiabatic Aharonov- Anandan geometric phase, measured by the area enclosed by the exact path, approaches smoothly the adiabatic Berry phase, proportional to the area enclosed by the adiabatic path. The singular limit of the time-energy uncertainty and the regular limit of the geometric phase are associated with the arc length and arc area of the cycloid on a Bloch sphere, respectively. Prolate and curtate cycloids are also traced by different initial states outside and inside of the rolling circle, respectively. The axis trajectory of the rolling circle, parallel to the adiabatic path, is shown to be an example of transitionless driving. The non-adiabatic resonance is visualized by the number of cycloid arcs.
Shedding light on ovothiol biosynthesis in marine metazoans
Authors: Castellano Immacolata , Migliaccio Oriana , D’Aniello Salvatore , Merlino Antonello , Napolitano Alessandra , Palumbo Anna 
Published: February 2016

AbstractOvothiol, isolated from marine invertebrate eggs, is considered one of the most powerful antioxidant with potential for drug development. However, its biological functions in marine organisms still represent a matter of debate. In sea urchins, the most accepted view is that ovothiol protects the eggs by the high oxidative burst at fertilization. In this work we address the role of ovothiol during sea urchin development to give new insights on ovothiol biosynthesis in metazoans. The gene involved in ovothiol biosynthesis OvoA was identified in Paracentrotus lividus genome (PlOvoA). PlOvoA embryo expression significantly increased at the pluteus stage and was up-regulated by metals at concentrations mimicking polluted sea-water and by cyclic toxic algal blooms, leading to ovothiol biosynthesis. In silico analyses of the PlOvoA upstream region revealed metal and stress responsive elements. Structural protein models highlighted conserved active site residues likely responsible for ovothiol biosynthesis. Phylogenetic analyses indicated that OvoA evolved in most marine metazoans and was lost in bony vertebrates during the transition from the aquatic to terrestrial environment. These results highlight the crucial role of OvoA in protecting embryos released in seawater from environmental cues, thus allowing the survival under different conditions.
Label-free imaging to study phenotypic behavioural traits of cells in complex co-cultures
Authors: Suman Rakesh , Smith Gabrielle , Hazel Kathryn E. A. , Kasprowicz Richard , Coles Mark , O’Toole Peter , Chawla Sangeeta 
Published: February 2016

AbstractTime-lapse imaging is a fundamental tool for studying cellular behaviours, however studies of primary cells in complex co-culture environments often requires fluorescent labelling and significant light exposure that can perturb their natural function over time. Here, we describe ptychographic phase imaging that permits prolonged label-free time-lapse imaging of microglia in the presence of neurons and astrocytes, which better resembles in vivo microenvironments. We demonstrate the use of ptychography as an assay to study the phenotypic behaviour of microglial cells in primary neuronal co-cultures through the addition of cyclosporine A, a potent immune-modulator.
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells
Authors: Askarian Fatemeh , Ajayi Clement , Hanssen Anne-Merethe , van Sorge Nina M. , Pettersen Ingvild , Diep Dzung B. , Sollid Johanna U. E. , Johannessen Mona 
Published: February 2016

AbstractStaphylococcus aureus is known as a frequent colonizer of the skin and mucosa. Among bacterial factors involved in colonization are adhesins such as the microbial surface components recognizing adhesive matrix molecules (MSCRAMMs). Serine aspartate repeat containing protein D (SdrD) is involved in adhesion to human squamous cells isolated from the nose. Here, we identify Desmoglein 1 (Dsg1) as a novel interaction partner for SdrD. Genetic deletion of sdrD in S. aureus NCTC8325-4 through allelic replacement resulted in decreased bacterial adherence to Dsg1- expressing HaCaT cells in vitro. Complementary gain-of-function was demonstrated by heterologous expression of SdrD in Lactococcus lactis, which increased adherence to HaCaT cells. Also ectopic expression of Dsg1 in HEK293 cells resulted in increased adherence of S. aureus NCTC8325-4 in vitro. Increased adherence of NCTC8325-4, compared to NCTC8325-4ΔsdrD, to the recombinant immobilized Dsg1 demonstrated direct interaction between SdrD and Dsg1. Specificity of SdrD interaction with Dsg1 was further verified using flow cytometry and confirmed binding of recombinant SdrD to HaCaT cells expressing Dsg1 on their surface. These data demonstrate that Dsg1 is a host ligand for SdrD.
Societal Burden and Correlates of Acute Gastroenteritis in Families with Preschool Children
Authors: Mughini-Gras Lapo , Pijnacker Roan , Heusinkveld Moniek , Enserink Remko , Zuidema Rody , Duizer Erwin , Kortbeek Titia , van Pelt Wilfrid 
Published: February 2016

AbstractGastrointestinal infection morbidity remains high amongst preschool children in developed countries. We investigated the societal burden (incidence, healthcare utilization, and productivity loss) and correlates of acute gastroenteritis (AGE) in families with preschoolers. Monthly for 25 months, 2000 families reported AGE symptoms and related care, productivity loss, and risk exposures for one preschooler and one parent. Amongst 8768 child-parent pairs enrolled, 7.3% parents and 17.4% children experienced AGE (0.95 episodes/parent-year and 2.25 episodes/child-year). Healthcare utilization was 18.3% (children) and 8.6% (parents), with 1.6% children hospitalized. Work absenteeism was 55.6% (median 1.5 days) and day-care absenteeism was 26.2% (median 1 day). Besides chronic enteropathies, antacid use, non-breastfeeding, and toddling age, risk factors for childhood AGE were having developmental disabilities, parental occupation in healthcare, multiple siblings, single-parent families, and ≤12-month day-care attendance. Risk factors for parental AGE were female gender, having multiple or developmentally-disabled day-care-attending children, antimicrobial use, and poor food-handling practices. Parents of AGE-affected children had a concurrent 4-fold increased AGE risk. We concluded that AGE-causing agents spread widely in families with preschool children, causing high healthcare-seeking behaviours and productivity losses. Modifiable risk factors provide targets for AGE-reducing initiatives. Children may acquire some immunity to AGE after one year of day-care attendance.
Sesquiterpene emissions from Alternaria alternata and Fusarium oxysporum: Effects of age, nutrient availability and co-cultivation
Authors: Weikl Fabian , Ghirardo Andrea , Schnitzler Jörg-Peter , Pritsch Karin 
Published: February 2016

AbstractAlternaria alternata is one of the most studied fungi to date because of its impact on human life – from plant pathogenicity to allergenicity. However, its sesquiterpene emissions have not been systematically explored. Alternaria regularly co-occurs with Fusarium fungi, which are common plant pathogens, on withering plants. We analyzed the diversity and determined the absolute quantities of volatile organic compounds (VOCs) in the headspace above mycelial cultures of A. alternata and Fusarium oxysporum under different conditions (nutrient rich and poor, single cultures and co-cultivation) and at different mycelial ages. Using stir bar sorptive extraction and gas chromatography–mass spectrometry, we observed A. alternata to strongly emit sesquiterpenes, particularly during the early growth stages, while emissions from F. oxysporum consistently remained comparatively low. The emission profile characterizing A. alternata comprised over 20 sesquiterpenes with few effects from nutrient quality and age on the overall emission profile. Co-cultivation with F. oxysporum resulted in reduced amounts of VOCs emitted from A. alternata although its profile remained similar. Both fungi showed distinct emission profiles, rendering them suitable biomarkers for growth-detection of their phylotype in ambient air. The study highlights the importance of thorough and quantitative evaluations of fungal emissions of volatile infochemicals such as sesquiterpenes.
The Transcriptional Landscape of the Photosynthetic Model Cyanobacterium Synechocystis sp. PCC6803
Authors: Hernández-Prieto Miguel A. , Semeniuk Trudi Ann , Giner-Lamia Joaquín , Futschik Matthias E. 
Published: February 2016

AbstractCyanobacteria exhibit a great capacity to adapt to different environmental conditions through changes in gene expression. Although this plasticity has been extensively studied in the model cyanobacterium Synechocystis sp. PCC 6803, a detailed analysis of the coordinated transcriptional adaption across varying conditions is lacking. Here, we report a meta-analysis of 756 individual microarray measurements conducted in 37 independent studies-the most comprehensive study of the Synechocystis transcriptome to date. Using stringent statistical evaluation, we characterized the coordinated adaptation of Synechocystis’ gene expression on systems level. Evaluation of the data revealed that the photosynthetic apparatus is subjected to greater changes in expression than other cellular components. Nevertheless, network analyses indicated a significant degree of transcriptional coordination of photosynthesis and various metabolic processes, and revealed the tight co-regulation of components of photosystems I, II and phycobilisomes. Detailed inspection of the integrated data led to the discovery a variety of regulatory patterns and novel putative photosynthetic genes. Intriguingly, global clustering analyses suggested contrasting transcriptional response of metabolic and regulatory genes stress to conditions. The integrated Synechocystis transcriptome can be accessed and interactively analyzed via the CyanoEXpress website (http://cyanoexpress.sysbiolab.eu).
Bias-polarity-dependent resistance switching in W/SiO2/Pt and W/SiO2/Si/Pt structures
Authors: Jiang Hao , Li Xiang Yuan , Chen Ran , Shao Xing Long , Yoon Jung Ho , Hu Xiwen , Hwang Cheol Seong , Zhao Jinshi 
Published: February 2016

AbstractSiO2is the most significantly used insulator layer in semiconductor devices. Its functionality was recently extended to resistance switching random access memory, where the defective SiO2played an active role as the resistance switching (RS) layer. In this report, the bias-polarity-dependent RS behaviours in the top electrode W-sputtered SiO2-bottom electrode Pt (W/SiO2/Pt) structure were examined based on the current-voltage (I-V) sweep. When the memory cell was electroformed with a negative bias applied to the W electrode, the memory cell showed a typical electronic switching mechanism with a resistance ratio of ~100 and high reliability. For electroforming with opposite bias polarity, typical ionic-defect-mediated (conducting filament) RS was observed with lower reliability. Such distinctive RS mechanisms depending on the electroforming-bias polarity could be further confirmed using the light illumination study. Devices with similar electrode structures with a thin intervening Si layer between the SiO2and Pt electrode, to improve the RS film morphology (root-mean-squared roughness of ~1.7 nm), were also fabricated. Their RS performances were almost identical to that of the single-layer SiO2sample with very high roughness (root-mean-squared roughness of ~10 nm), suggesting that the reported RS behaviours were inherent to the material property.