bluuebunny/crossref_metadata_2025_split huggingface dataset:
TAT-1, a phosphatidylserine flippase, affects molting and regulates membrane trafficking in the epidermis ofC. elegans
Authors: Milne Shae M. , Edeen Philip T. , Fay David S. 
Published: September 2024

ABSTRACTMembrane trafficking is a conserved process required for the movement and distribution of proteins and other macromolecules within cells. TheCaenorhabditis elegansNIMA-related kinases NEKL-2 (human NEK8/9) and NEKL-3 (human NEK6/7) are conserved regulators of membrane trafficking and are required for the completion of molting. We used a genetic approach to identify reduction-of-function mutations intat-1that suppressnekl-associated molting defects.tat-1encodes theC. elegansortholog of mammalian ATP8A1/2, a phosphatidylserine (PS) flippase that promotes the asymmetric distribution of PS to the cytosolic leaflet of lipid membrane bilayers. CHAT-1 (human CDC50), a conserved chaperone, was required for the correct localization of TAT-1, andchat-1inhibition strongly suppressednekldefects. Using a PS sensor, we found that TAT-1 was required for the normal localization of PS at apical endosomes and that loss of TAT-1 led to aberrant endosomal morphologies. Consistent with this, TAT-1 localized to early endosomes and to recycling endosomes marked with RME-1, theC. elegansortholog of the human EPS15 homology (EH) domain-containing protein, EHD1. TAT-1, PS biosynthesis, and the PS-binding protein RFIP-2 (human RAB11-FIP2) were all required for the normal localization of RME-1 to apical endosomes. Consistent with these proteins functioning together, inhibition of RFIP-2 or RME-1 led to the partial suppression ofneklmolting defects, as did the inhibition of PS biosynthesis. Using the auxin-inducible degron system, we found that depletion of NEKL-2 or NEKL-3 led to defects in RME-1 localization and that a reduction in TAT-1 function partially restored RME-1 localization in NEKL-3–depleted cells.ARTICLE SUMMARYEndocytosis is an essential process required for the movement of proteins and lipids within cells. NEKL-2 and NEKL-3, two evolutionarily conserved proteins in the nematodeCaenorhabditis elegans, are important regulators of endocytosis. In the current study, the authors describe a new functional link between the NEKLs and several proteins with known roles in endocytosis including TAT-1, a conserved enzyme that moves lipids between the bilayers of cellular membranes. As previous work implicated NEKLs in developmental defects and cancer, the present study can provide new insights into how the misregulation of endocytosis affects human health and disease.
Do organizations based in Poland need identity leadership? Polish adaptation of the short and full form of identity leadership inventory
Authors: Retowski Sylwiusz , Godlewska-Werner Dorota , van Dick Rolf 
Published: September 2024

PurposeThe study aimed to test the validity and reliability of the Polish version of the identity leadership inventory (ILI) proposed by Steffens, Haslam, Reicher et al. (2014) and to confirm the relationship between identity leadership and various job-related outcomes (i.e., trust in leaders, job satisfaction, work engagement and turnover intentions) among employees from Poland-based organizations. Identity leadership appears to be a universal construct (van Dick, Ciampa, & Liang, 2018) but no one has studied it in Poland so far.Design/methodology/approachThe sample consisted of 1078 employees collected in two independent subsamples from different organizations located in Northern and Central Poland. We evaluated the ILI’s factorial structure using confirmatory factor analysis.FindingsThe results confirm that the 15-item Polish version of the ILI has a four-dimensional structure with factors representing prototypicality, advancement, entrepreneurship and impresarioship. It showed satisfactory reliability. The identity leadership inventory-short form (four items) also showed a good fit with the data. As expected, the relationships between identity leadership and important work-related outcomes (general level of job satisfaction, work engagement, trust toward the leader and turnover intentions) were also significant.Originality/valueDespite the cultural specifics of Polish organizations, the research results were generally very similar to those in other countries, confirming the universality of the ILI as shown in the Global Identity Leadership Development project (GILD, see van Dick, Ciampa, & Liang, 2018; van Dick et al., 2021).
Determinants of SMEs' strategic entrepreneurial innovative digitalization: examining the mediation role of human capital
Authors: Hossain Md Billal , Rahman Mujib Ur , Čater Tomaž , Vasa László 
Published: September 2024

PurposeThis study was inspired by research of strategists on strategic innovation (SI), aiming to provide a unique model to enhance the digitization of small and medium-sized enterprises (SMEs) in Bangladesh to fill the gap toward a digital economy.Design/methodology/approachA survey was used to collect data from 180 SMEs in the manufacturing industry for this research. The results indicate that strategic innovativeness (SI), human capital (HC), infrastructure and technology and resistance to change significantly influence the digitalization in Bangladesh SMEs.FindingsThe link between SI and SMEs' digitalization in Bangladesh is mediated by HC. The results show that HC plays a big role in the connection between SI and the digitalization of SMEs. This study may be valuable for SMEs managers, researchers and policymakers in Bangladesh and other developing nations, who want to learn more about SI in adopting digitalization.Originality/valueThe specialized knowledge and abilities of strategists allow them to establish parallels between the past and present, enabling them to make a sustained forecast about the digital economy. This study encourages small and medium-sized businesses to develop their SI and advance their HC, which could further deject resistance to change toward enhancing and adopting digitalization in SMEs sectors.
Beyond liberalization: employers’ organizations’ varied responses to employment law
Authors: Gooberman Leon , Hauptmeier Marco , Heery Edmund 
Published: September 2024

PurposeA key meta-narrative of Employment Relations in the UK over recent decades has been that of labour market deregulation. However, governments have simultaneously introduced workplace rights legislation that juridified individual employment relationships. Within this process, employers and their representatives, Employers’ Organizations (EOs), are generally depicted as opposing the introduction of employment law or attempting to weaken its application. Contrary to this belief, our research identified a range of other responses to ask: how and why have EO responses varied?Design/methodology/approachThis article draws on primary qualitative and quantitative data from three projects; one examined the totality of EOs in the UK while the others examined topic-specific behaviour of EOs and other actors. The main source is the first project and its 98 interviews with representatives of EOs and related organisations between 2013 and 2017.FindingsWe demonstrate that opposition is not the only EO response to individual employment law by identifying three others: compliance, advocating for law and going beyond legally stipulated requirements by promoting voluntary standards/best practice. The article argues that there are two explanations for this pattern. One is that individual EOs possess different sets of member interests, the other relates to differences in their organizational characteristics.Originality/valueThe article makes two contributions to the literature. One is that our identification of varying responses challenges more unitary accounts emphasising neoliberal and deregulatory patterns. The other lies in our identification of causal forces not previously identified. Both combine to illustrate how the neo-liberal order is not characterised by employer consensus as to regulation.
Computational study on cilia transport of Prandtl nanofluid (blood-Fe3O4) enhancing convective heat transfer along microorganisms under electroosmotic effects in wavy capillaries
Authors: Ajmal Madiha , Mehmood Rashid , Akbar Noreen Sher , Muhammad Taseer 
Published: September 2024

Purpose
This study aims to focuse on the flow behavior of a specific nanofluid composed of blood-based iron oxide nanoparticles, combined with motile gyrotactic microorganisms, in a ciliated channel with electroosmosis.

Design/methodology/approach
This study applies a powerful mathematical model to examine the combined impacts of bio convection and electrokinetic forces on nanofluid flow. The presence of cilia, which are described as wave-like motions on the channel walls, promotes fluid propulsion, which improves mixing and mass transport. The velocity and dispersion of nanoparticles and microbes are modified by the inclusion of electroosmosis, which is stimulated by an applied electric field. This adds a significant level of complexity.

Findings
To ascertain their impact on flow characteristics, important factors such as bio convection Rayleigh number, Grashoff number, Peclet number and Lewis number are varied. The results demonstrate that while the gyrotactic activity of microorganisms contributes to the stability and homogeneity of the nanofluid distribution, electroosmotic forces significantly enhance fluid mixing and nanoparticle dispersion. This thorough study clarifies how to take advantage of electroosmosis and bio convection in ciliated micro channels to optimize nanofluid-based biomedical applications, such as targeted drug administration and improved diagnostic processes.

Originality/value
First paper discussed “Numerical Computation of Cilia Transport of Prandtl Nanofluid (Blood-Fe3O4) Enhancing Convective Heat Transfer along Micro Organisms under Electroosmotic effects in Wavy Capillaries”.
An efficient three-dimensional node localization using recurrent neural networks in unmanned aerial vehicle-assisted wireless networks: an optimization perspective
Authors: Negassa Workeneh Geleta , Gelmecha Demissie J. , Singh Ram Sewak , Rathee Davinder Singh 
Published: September 2024

PurposeUnlike many existing methods that are primarily focused on two-dimensional localization, this research paper extended the scope to three-dimensional localization. This enhancement is particularly significant for unmanned aerial vehicle (UAV) applications that demand precise altitude information, such as infrastructure inspection and aerial surveillance, thereby broadening the applicability of UAV-assisted wireless networks.Design/methodology/approachThe paper introduced a novel method that employs recurrent neural networks (RNNs) for node localization in three-dimensional space within UAV-assisted wireless networks. It presented an optimization perspective to the node localization problem, aiming to balance localization accuracy with computational efficiency. By formulating the localization task as an optimization challenge, the study proposed strategies to minimize errors while ensuring manageable computational overhead, which are crucial for real-time deployment in dynamic UAV environments.FindingsSimulation results demonstrated significant improvements, including a channel capacity of 99.95%, energy savings of 89.42%, reduced latency by 99.88% and notable data rates for UAV-based communication with an average localization error of 0.8462. Hence, the proposed model can be used to enhance the capacity of UAVs to work effectively in diverse environmental conditions, offering a reliable solution for maintaining connectivity during critical scenarios such as terrestrial environmental crises when traditional infrastructure is unavailable.Originality/valueConventional localization methods in wireless sensor networks (WSNs), such as received signal strength (RSS), often entail manual configuration and are beset by limitations in terms of capacity, scalability and efficiency. It is not considered for 3-D localization. In this paper, machine learning such as multi-layer perceptrons (MLP) and RNN are employed to facilitate the capture of intricate spatial relationships and patterns (3-D), resulting in enhanced localization precision and also improved in channel capacity, energy savings and reduced latency of UAVs for wireless communication.
The impact of board diversity on earnings management in Kuwait
Authors: Alqatan Ahmad 
Published: September 2024

Purpose
This paper aims to examine the consequences of board diversity (BD) in Kuwait. In particular, it examines the impact of BD (gender, age and nationality) on earnings management (EM).

Design/methodology/approach
The research uses data from 103 non-financial Kuwaiti-listed companies from 2010 to 2017. The data is collected from the companies’ data from secondary sources such as their annual reports. The data analysis methods are correlation, multi-regression and robust regression. EM is measured using the modified Jones model (1995) and Kothari et al. (2005).

Findings
The findings show a negative association between gender diversity (GD) and EM. It also found a positive relationship between age diversity (AD) and EM and no relationship between national diversity (ND) and EM.

Practical implications
This study’s results have significant implications for investors. The practical empirical findings indicate that GD on the board did not impact on EM. Also, it is more important to have senior directors on the board than AD to reduce EM. There is no need to employ any foreigners because they do not affect EM.

Originality/value
It contributes to the growing body of literature on BD by investigating its effect on EM. Furthermore, building on the broader literature on gender, age and ND by highlighting the critical role that women, young people and foreign directors play in improving boards' monitoring role on EM. More specifically, it contributes to existing knowledge, provides a theoretical contribution and makes a methodological contribution.
Fostering employee autonomy through rewards: a self-determination theory perspective
Authors: Zeshan Muhammad , Rasool Shahid , Di Prima Christian , Ferraris Alberto 
Published: September 2024

Purpose
This paper aims to explain and determine the effect of rewards on employees’ autonomy by investigating the mediating effect of enabling controls on their relationship.

Design/methodology/approach
A three-wave survey strategy has been used to collect data from the alumni of a French business school. Structural equation modelling has been used for measures validating and hypotheses testing.

Findings
The study reveals a positive relationship between rewards and autonomy, mediated by enabling controls.

Practical implications
The study guides the process of administrating rewards to employees in a way that maximizes their autonomy, highlighting the crucial role of supervisors through enabling controls.

Originality/value
The study strives to create consensus regarding the long-existing debate on the effect of rewards on employees’ autonomy with the help of organizational theory literature. By considering the role of enabling controls, it provides a unique, cohesive framework to illustrate the intertwined relationship between the constructs.
Metabolic disturbances in normal-weight obesity: a cross-sectional study of Iranian employees
Authors: Masoumi Seyed Jalil , Kohanmoo Ali , Mohsenpour Mohammad Ali , Jamshidi Sanaz , Eftekhari Mohammad Hassan 
Published: September 2024

Purpose
Normal-weight obesity (NWO), characterized by normal body mass index (BMI) but excess body fat, is a potential contributor to chronic diseases. This study aims to assess the relationship between this phenomenon and some metabolic factors in a population of Iranian employees.

Design/methodology/approach
This cross-sectional study was conducted on Iranian employees from the baseline data of Employees Health Cohort Study, Shiraz, Iran. Anthropometric measures, including weight, height, waist circumference and percentage of body fat, were obtained from the cohort database. The participants were divided into three groups: healthy, normal-weight obese and overweight/obese. Metabolic variables including blood pressure, fasting blood sugar, lipid profile, liver function enzymes and metabolic syndrome were assessed in relation to the study groups.

Findings
A total of 985 participants aged 25–64 years were included. Males with NWO had significantly higher alanine aminotransferase (ALT) levels compared to the healthy group in the fully adjusted model. Also, high-density lipoprotein (HDL) was significantly lower among females with overweight/obesity than healthy group when adjusted for age and energy intake. Furthermore, after adjusting for age and energy intake, both genders in the overweight/obese group showed significantly elevated systolic and diastolic blood pressure, while this was not observed for the NWO group. Lastly, metabolic syndrome was more prevalent in NWO as well as overweight/obesity.

Originality/value
These findings further encourage identification of excess body fat, even in normal-weight individuals, to prevent chronic metabolic diseases. Special attention should be paid to subgroups with sedentary occupations, as they may be at increased risk for NWO-related health issues.
Assessing the sustainable alignment of a sensor-based connected health system with SDGs: an evaluation model and case study
Authors: Díaz Jiménez David , López Ruiz José Luis , González Lama Jesús , Verdejo Espinosa Ángeles 
Published: September 2024

PurposeThe main objective of the study is to address the lack of sustainability assessments of smart connected health systems in the academic literature by presenting an assessment model to determine the alignment of these systems with the 17 Sustainable Development Goals (SDGs) proposed in the 2030 Agenda.Design/methodology/approachAn evaluation model based on decision analysis is proposed that includes three phases: alignment framework, information gathering and assessment. This model measures the alignment of the connected health system with each of the 17 SDGs, identifying the goals and criteria associated with each SDG that the system achieves to satisfy.FindingsThe analysis reveals that the system has achieved more than 24% of the targets among the 17 SDGs. In addition, it identifies four sustainability challenges that the system potentially addresses in relation to the SDGs, providing valuable guidance for researchers and practitioners interested in sustainable health technology development.Practical implicationsThe study's results have significant implications for policymakers and stakeholders in the health and technology sectors.Originality/valueThe originality of this study lies in its comprehensive approach to assessing the sustainability of connected health systems in the context of the SDGs, filling an important gap in the existing literature.
An improved affine mixed‐grid method for frequency‐domain finite‐difference elastic modelling
Authors: Dong Shu‐Li , Chen Jing‐Bo 
Published: September 2024

AbstractIn seismic frequency‐domain finite‐difference modelling, the affine mixed‐grid method effectively eliminates the spatial sampling restriction associated with square meshes of the rotated mixed‐grid method. Nevertheless, the affine mixed‐grid method makes a weighted average of the entire elastic wave equations, resulting in reduced accuracy compared to the average‐derivative method in the case of rectangular meshes. It is worth noting, however, that the average‐derivative method is presently inapplicable to free‐surface scenarios, whereas the affine mixed‐grid method is applicable. By performing weighted averages of the derivative terms instead of the entire elastic wave equations in Cartesian and affine rotated coordinate systems, we have developed an improved affine mixed‐grid method for elastic‐wave frequency‐domain finite‐difference modelling. The proposed improved affine mixed‐grid method 9‐point scheme overcomes the drawback that the accuracy of affine mixed‐grid method is lower than that of average‐derivative method for unequal directional grid intervals. Moreover, the improved affine mixed‐grid method 6‐point scheme provides much higher numerical accuracy than the affine mixed‐grid method 6‐point scheme at either equal or unequal directional grid intervals. On the other hand, the proposed improved affine mixed‐grid method simplifies the coding complexity for implementing free‐surface condition in elastic‐wave frequency‐domain finite‐difference modelling by modifying the elastic parameters of the free‐surface layer and thus constructing the impedance matrix containing the free‐surface condition directly.
Investigation of isotopic linkages between raw materials and black powder
Authors: Hu Can , Huang Yang , Mei Hongcheng , Guo Hongling , Wang Ping , Li Yajun , Deng Xianhe , Zhu Jun 
Published: September 2024

AbstractThe stable isotope analysis of black powder (BP) is of great significance for its comparison and source inference. Previous studies have verified the feasibility of distinguishing different BP samples through stable isotopes. However, the impact of raw materials and synthesis processes on the stable isotopes of BP remains unclear. On the one hand, the raw materials of BP are widely sourced, and whether stable isotopes can distinguish different source materials remains to be studied. On the other hand, the synthesis of BP involves the physical mixing of raw materials, and whether this process leads to isotope fractionation also needs further investigation. To address these problems, stable isotope ratios of 27 charcoals, 15 potassium nitrates, 6 self‐made and 10 commercial BP samples were analyzed. The results showed that the stable isotope ratios can be utilized to distinguish charcoals and potassium nitrates from different manufacturers and batches. No significant differences in the nitrogen and oxygen stable isotope ratios between the self‐made BP and its raw materials were observed, indicating that the physical mixing process does not induce significant fractionation of stable isotopes. However, the carbon stable isotope ratios of charcoal increased (within 2SD) after being synthesized into BP. Due to the utilization of additives and variations in the synthesis process, the correlation between the stable isotope ratios of commercial BP and its raw materials was complex. The findings of this study provide a scientific reference for tracing the source of BP.