bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Kusha Swarasa in the Management of Mootravaha Sroto Dusti Vikara
Authors: Chavhan Nagaraj Naik , Shashirekha H.K. , Bargale Sushant Sukumar 
Published: September 2024

Mutravaha Srotas is one among the Abhyantara Srotas, concerned with Utpatti, Visarjana of Mutra and maintaining the Kledata in the body. Causes for kidney function are not specific and might include Obstruction of urination, burning micturition, excessive urination, scanty urination, feeling generally unwell, having a reduced appetite over a period of long duration. Among Trinapanchmula Kusha is the one that promote the urine formation thereby flushing the kidneys and urinary tract while eliminating any excess water retention, and to remove the Mutra from the body. In day today practice it is not up to the mark being Ayurveda Profesionalists as limited utility of Trinapanchamoola in therapeutic usage were common community uses in the form of grass juice in their routine practice for accurate documentation. Here an effort made to understand the utility of drug Kusha Swarasa in clinical practice for the management of Mootravaha sroto vikara. Aims and objectives: To evaluate the effect Kusha of on Mutravaha Srotas. Materials and methods: 30 elderly peoples aged between 60 to 75 years are selected by random sampling method and separated as control and study group. Fresh Leaves of the Kusha grass is taken, juice is extracted and given as per the standard dose of Swarasa. It is given in early morning before having the food for 7 days along with Madhu is used as Anupana and 15 days follow up is done. Observations and result: Kusha Swarasawas effective in elderly old age peoples. Discussion and Conclusion: Kusha Swarasa is significantly effective in treating Mutravaha Sroto Dusti Lakshana of apparently healthy elderly old age peoples.
Keywords- Jara, Kusha, Mutravaha Srotas, Srotas.
The Development and Validation of Stability Indicating HPLC Method for Estimation of Darunavir
Authors: Chabukswar Anurruddha R. , Gadekar Ayushi S 
Published: September 2024

To develop a new simple, precise and accurate HPLC method for estimation of Darunavir in tablet formulation. An isocratic, HPLC method was developed using C-18, 50 x 3 mm, 3.5 µm (X-Terra MS, Waters) column 0.1 % Acetic acid in water: ACN (63:37 v/v) as mobile phase at flow rate of 1.0 ml/min at detection wavelength of 267 nm. The retention time (RT) of drug was 3.123± 0.034 min . The method was validated with respect to linearity, precision, assay, accuracy and robustness. The data of linear regression analysis indicated a good linear relationship over the range of 5-30 μg/ml concentrations with a correlation coefficient(R 2) of 0.9995.The developed method was found to be simple, sensitive, selective, accurate, and precise for analysis of Darunavir and can be adopted for routine analysis of drug in bulk and pharmaceutical dosage form.
Keywords: High performance liquid chromatography (HPLC), Darunavir, method development, Validation.
Nanotechnology: Emerging Platform for Drug Based Delivery System in Cancer
Authors: Misra Charu , Gaur Manish , Gupta Laxmi Narayan 
Published: September 2024

In present scenario cancer has become one of the most difficult global healthcare problems, despite of having library of anti-cancer drugs the problem remains the same due to no specificity, burst release, damaging of normal cells and numerous side effects. Nanotechnology the emerging field gained attention as it offers site specific treatment in various tumors with lesser side effect. Nano carriers, a transport module provide platform to circumvent the problems related with the delivery of anticancer drug in drug delivery systems. Nano carriers help to improve the bioavailability and therapeutic efficiency of antitumor drugs, while providing preferential accumulation at the target site. Various nanocarriers are clinically approved for the delivery of antitumor drugs for their intended actions at the targeted sites. This review illustrates about the various nanocarriers, their importance in the delivery of anticancer drugs, targeting mechanisms of nanoparticles, various method of preparations of nanoparticles and influence of nanotechnology on herbal drug.
Keywords: Nanocarrier, bioavailability, multi drug resistance,
A STUDY ON ANTIBACTERIAL PROPERTY OF HERBAL-BIOPOLYMER NANOENCAPSULATE TREATED FABRIC
Authors: Banupriya J. , Maheshwari V. 
Published: September 2024

The present study deals with the eco friendly antibacterial finish that has been integrated into bamboo/cotton woven treated fabric in the form of nanocapsules using ethanolic terminalia chebula, Rosmarinus officinalis and Opuntia littoralis (2:1:2) ratio and Chitosan biopolymer extracts by exhaust method in order to reduce the bacterial growth on the fabric. This herbals-biopolymer extract was evaluated for activity against medically challenging bacteria such as Staphylococcus aureus and Escherichia coli. The in-vitro antibacteria were performed by AATCC 147 for the treated nanoencapsule coated sample. Then the coated sample was analyzed for morphology using FTIR, FESEM and Cytotoxicity test. Thus the study supports the concept of nano encapsulation providing better additional properties to bamboo/cotton fabric and the application of nanotechnology is one of the supreme ways for humanizing the antibacterial activity.
Buku Ensiklopedia Berbasis Augmented Reality Mengenai Materi Sistem Respirasi Manusia
Authors: Nyoman Maesha Bramanda  , I Wayan Sujana  , Ni Wayan Suniasih  
Published: September 2024

Rendahnya hasil belajar IPAS disebabkan kurangnya bahan ajar yang mampu memvisualisasikan secara konkret dalam pembelajaran. Tujuan penelitian ini yaitu mengembangkan buku ensiklopedia berbasis AR. Jenis penelitian digunakan yaitu penelitian pengembangan dengan model Borg and Gall. Subek yang terlibat dalam penelitian yakni ahli isi pembelajaran, ahli desain pembelajaran, ahli media pembelajaran, uji coba perorangan, uji coba kelompok kecil, dan 35 orang siswa kelas V. Pengumpulam data dilakukan dengan metode observasi, wawancara dan penyebaran angket/kuisioner. Teknik analisis data yang digunakan ada tiga yaitu analisis data deskriptif kualitatif, kuantitatif, dan stastistik inferensial. Hasil penelitian yaitu validator ahli rancang bangun sebesar 93,18%, validator ahli isi materi memperoleh 95,83%, validator ahli desain instruksional memperoleh 93,18%, validator ahli media pembelajaran memperoleh 92,50%, uji coba perorangan memperoleh 99%, dan uji coba kelompok kecil memperoleh 97,5% yang bearti buku ensiklopedia berbasis AR sangat layak digunakan. Disimpulkan buku ensiklopedia berbasis augmented reality efektif diterapkan pada mata pelajaran IPAS. Implikasi penelitian ini bahwa penggunaan materi pembelajaran yang diintegrasikan dengan Augmented Reality cocok digunakan pada masa sekarang.
Analysis of User Satisfaction Level in MyUnnes Financial System Using the EUCS Method
Authors: Setyanto Roberthus , Ridloah Siti , Basit Asman Abdul 
Published: September 2024

Di era perkembangan yang semakin canggih dan berkembang pesat, tanpa kita sadari teknologi sangat berperan penting dalam rutinitas kegiatan sehari-hari. Salah satu perkembangannya yaitu sistem informasi keuangan. MyUnnes-Keuangan merupakan sebuah portal bagi mahasiswa Unnes untuk mengetahui data-data keuangan akademik dan kemahasiswaan tanpa membuka aplikasi lainnya. Untuk menjaga kualitas sebuah sistem informasi diperlukan evaluasi dari faktor kepuasan pengguna. Salah satu metode yang digunakan untuk menganalisis kepuasan pengguna terhadap sistem informasi adalah End User Computing Satisfaction (EUCS). Tujuan dari penelitian ini adalah untuk mengetahui tingkat kepuasan pengguna Sistem Informasi MyUnnes-Keuangan menggunakan metode End User Computing Satisfaction (EUCS) di Universitas Negeri Semarang. Berdasarkan analisis dengan metode EUCS, maka diperoleh hasil variabel content dan variabel accuracy memiliki persentase masing-masing 73% dan 72% yang termasuk kedalam kategori baik. Variabel ease of Use memiliki persentase sebesar 93% yang termasuk kedalam kategori sangat baik. Variabel timeliness dan variabel satisfaction memiliki persentase masing-masing 69% dan 73% yang termasuk kedalam kategori baik, Saran untuk penelitian selanjutnya diharapkan dapat dilakukan pengembangan aplikasi MyUnnes-Keuangan dengan dilakukannya analisis kebutuhan berdasarkan penelitian sebelumnyaKata kunci : Sistem Informasi Keuangan, Kepuasaan, End User Computing Satisfaction. In an era of increasingly advanced and rapid development, technology plays a crucial role in our daily routines, often without us realizing it. One of the developments is financial information systems. MyUnnes-Financial is a portal for Unnes students to access academic and student financial data without the need for other applications. To maintain the quality of an information system, user satisfaction evaluation is necessary. One of the methods used to analyze user satisfaction with information systems is End User Computing Satisfaction (EUCS). The aim of this research is to assess the level of user satisfaction with the MyUnnes-Financial Information System using the End User Computing Satisfaction (EUCS) method at the State University of Semarang. This type of research is descriptive research that uses a qualitative approach. Based on the EUCS analysis, the results show that the content and accuracy variables have a percentage of 73% and 72%, respectively, which fall into the "good" category. The ease of use variable has a percentage of 93%, which is considered "excellent." The timeliness and satisfaction variables each have a percentage of 69% and 73%, placing them in the "good" category. For future research, it is suggested that application development for MyUnnes-Financial be conducted, considering the needs based on previous research.Keywords: Financial Information System, Satisfaction, End User Computing Satisfaction.
Analisis Break Even Point pada Usaha Peternakan Ayam Broiler dengan Sistem Pemeliharaan Sistem Closed House
Authors: Batu Helda R. Lumban , Fitriani Anita , Firman Achmad 
Published: September 2024

Break Even Point merupakan salah satu teknik yang digunakan untuk mengetahui kondisi usaha dalam menjalankan aktivitasnya tidak mendapatkan laba dan tidak mengalami kerugian atau pengeluaran sama dengan penerimaan. Penelitian ini dilakukan untuk mengetahui nilai Break Even Point pada usaha peternakan ayam broiler dengan skala kepemilikan besar di Desa Cigendel Kecamatan Pamulihan Kabupaten Sumedang. Jumlah populasi ternak broiler pada usaha ini adalah 67.000 ekor. Metode yang digunakan pada penelitian ini adalah studi kasus yang bersifat deskriptif analisis dengan teknik pengumpulan data observasi, wawancara dan dokumentasi. Variabel yang diamati adalah biaya produksi, harga jual, volume penjualan,. Berdasarkan hasil penelitian, rata-rata total biaya produksi per periode adalah Rp 2.239.657.788. Rata-rata penerimaan per periode produksi adalah Rp 2.436.708.944. Rata-rata BEP yang diperoleh adalah 33.365 unit dan nilai BEP dalam rupiah adalah Rp 675.052.532. Pada posisi tersebut peternak tidak mendapatkan keuntungan dan kerugian.
The Relationship Between Perceptions of Livestock Participation Rates in the Dairy Cattle Business Insurance Program
Authors: Lyviani Aninda Chika , Sulistyati Marina , Yunasaf Unang 
Published: September 2024

The majority of dairy cattle businesses in Indonesia are smallholder farmers. The government has tried various ways to increase domestic fresh milk production, one of which is increasing the number of intensive dairy cattle in the form of various facilities such as assistance programs, Asuransi Usaha Ternak Sapi (AUTS). Koperasi Unit Desa (KUD) Sarwa Mukti is one of the cooperatives engaged in the dairy cattle business in the Bandung Barat Regency area that received AUTS assistance. Research is needed to see the relationship between perception (cognition and affection) with the level of farmer participation in the AUTS program at KUD Sarwa Mukti. The results of this study can be a source of information and input for all livestock groups, KUD Sarwa Mukti and AUTS organizers for the progress of the program. This research is a survey with purposive sampling and simple random sampling and the outputs are Spearman rank correlation analysis and the interpretation of the degree of relationship with Guilford's rule. A total of 67 farmers with 1-20 dairy cows were the respondents of this study. The results obtained, the perception of dairy farmers who are members of the KUD Sarwa Mukti towards the AUTS program is in the high category (49.3%). Participation in the decision-making, implementation, and utilization stages of the results of dairy farmers who are members of the KUD Sarwa Mukti towards the AUTS program is at a moderate level (82.09%). There is a weak positive relationship between the perception and participation of dairy farmers who are members of the KUD Sarwa Mukti on the AUTS program, with a Spearman Rank correlation coefficient with Guilford's rule of 0.253.
Ultrasound biomicroscopy in dogs suggests postoperative ocular hypertension may be associated with ciliary cleft changes related to cataract surgery
Authors: Smith Hannah L. , Love Kim R. , Westermeyer Hans D. 
Published: September 2024

Abstract

OBJECTIVE
To determine whether novel pre- and postsurgical ultrasound biomicroscopy (UBM) measurements of the canine ciliary cleft (CC) are associated with postoperative ocular hypertension (POH) following cataract surgery and to explore the relationship between intraocular pressure and CC UBM measurements.

METHODS
Following pharmacologic mydriasis, UBM images were obtained from 31 client-owned dogs before elective cataract surgery, immediately postsurgery, and 4 to 6 hours following surgery or while experiencing POH ≥ 25 mm Hg. Presurgery and the pre- to postsurgery change in CC measurements were assessed for association with POH using individual mixed-effects logistic regression models and forward variable selection models. Linear mixed-effects models were used to evaluate the relationship of intraocular pressure to UBM measurements within the same eye across multiple time points.

RESULTS
Presurgical measurements were not predictive of POH development. An increase in pectinate ligament distance and CC area from presurgical baseline to immediate postsurgical measurement was associated with reduced odds of developing POH, while increasing CC length (from apex to mid point on the pectinate ligament) from pre- to postsurgery and immature cataracts was associated with increased odds of POH.

CONCLUSIONs
The change in CC morphology following cataract surgery appears more impactful in the development of POH than individual variations in presurgery CC measurements. Several changes in the CC dimensions following surgery appear associated with POH risk.

CLINICAL RELEVANCE
This understanding of a potential mechanism of POH development opens new avenues for researching preventative measures associated with modifying surgical techniques to influence CC morphology following cataract surgery.
Bitemporal aerial laser scans as an alternative to site index estimation: A case study in the Bohemian Switzerland National Park
Authors: Melichová Zlatica , Vébrová Dana , Marušák Robert , Surový Peter 
Published: September 2024

Abstract
In this work, we present a study about the application of bi-temporal, large interval aerial laser scans for constructing of tree growth models and estimating site index quality based on the measured increments from the laser scans. We compared two LiDAR scans with 14 years of difference in the national park area, where most areas are unmanaged. We derived the increment curve based on the Chapman-Richard growth formula. We used site index estimates from forest management plans from the national scale as the ground truth (both absolute and relative). We constructed three predictive models for site index estimates from bi-temporal scans, in modalities with and without stand age. Including the stand age improved all models, but even without the age, the models performed relatively well for differentiation between better and worse sites. At this moment, it is not directly possible to estimate age from remotely sensed data, but consistent monitoring, with laser scanning or photogrammetry, undoubtedly detects the harvest or dieback, so in the future, age can be considered as a variable easily estimated from remotely sensed data and so remote sensed material are viable source for understanding of forest growth and production.
The protective role of canopy cover against cork oak decline in the face of climate change
Authors: Ribeiro João , Camilo-Alves Constança , Ribeiro Nuno de Almeida 
Published: September 2024

Abstract
Cork oak (Quercus suber L.) mortality has reached alarming proportions in the last decades, exacerbated by climate change. Understanding this phenomenon is crucial in finding mitigation or adaptation strategies. This study conducts a diachronic analysis of cork oak mortality over 10 years using GIS (Geographic Information Systems) tools, focusing on Portugal’s Tagus Lezíria region. Topographic, edaphic and climatic variables were employed to create maps of edaphoclimatic aptitude for cork oaks. Dead trees were identified using remote sensing techniques and crown coverage was determined to calculate the trees’ mortality index. The diachronic analysis aimed the exploration of climate change effects on cork oak mortality. A decrease in precipitation was observed, significantly impacting stands with canopy cover below 40%. Furthermore, a negative effect of solar radiation identified only in stands with canopy cover of 40% suggested its role in cork oak decline. This study introduces a novel perspective, highlighting the protective effect of denser canopy cover against excessive solar radiation and the impact of reduced precipitation. The integrated and diachronic approach provides valuable information for adapting management strategies to climate change challenges.
Analysis of Rural Producers' Performance Indicators: a Case Study of Cooperative Members of the Southern Bahia Cocoa Indication of Origin
Authors: Pereira Maria Gabriella Alves , Lima Angela Maria Ferreira , Sant'Ana Cristiano de Souza , Martins Luís Oscar Silva , Silva Marcelo Santana 
Published: September 2024

Objective: The aim of this study is to investigate performance indicators for cocoa in the southern region of Bahia for the period 2021-2023.

Theoretical Framework: Through a literature review, this study aims to understand the concepts and connections between Geographical Indication and its impacts on socio-economic development as a basis for analyzing qualitative data collected from the Cacau Sul da Bahia Association and the Brazilian Micro and Small Business Support Service to evaluate and compare the impacts over time.

Method: An applied and exploratory approach was used, using secondary data, which was analyzed according to Bardin's (1997) proposal.

Results and Discussion: The research shows the seasonality of cocoa production in the south of Bahia, with production peaks in July, the peak harvest season. Production stability is suggested for the 2021-2023 period. The geographical distribution of producers showed a concentration of production in a few municipalities, as well as the fact that only five maintained regularities over the three years.

Research Implications: The research implies the need for management and planning strategies to ensure the sustainability of the sector and promote greater participation by municipalities in cocoa production in the region.

Originality/Value: This study proposes a comprehensive assessment of the socio-economic and environmental impacts in a region with a product protected by Geographical Indication.
Human Rights in Science: Observations From Ethics Committees on Medical Research Protocols
Authors: Vasco-Morales Santiago , Vasco-Toapanta Cristhian , Guanoluisa-Vasco Alisson , Vasco-Toapanta Gabriel , Toapanta-Pinta Paola 
Published: September 2024

Objective: To determine the frequency with which Research Ethics Committees (RECs) identify breaches of ethical principles in research protocols.

Theoretical Framework: Ethical principles in human research are established in the Nuremberg Code (informed consent and the common good), the Declaration of Helsinki (protection of vulnerable groups), and the Belmont Report (autonomy, beneficence, and justice). These principles are monitored by RECs to protect participants and ensure fairness in resource use. Informed consent ensures autonomy and the integrity of the research.

Method: Searches were conducted in PubMed, Scopus, and Google Scholar up to November 30, 2023. A meta-analysis of single proportions was performed. PROSPERO Registration: CRD42021291893

Results and Discussion: Nine publications were reviewed, revealing violations of the principle of justice in up to 100% of protocols. In Latin America, violations were observed in 9% (95% CI: 7-12) of protocols, while in Europe, the rate was 15% (95% CI: 9-24). Autonomy was observed in 26% (95% CI: 20-33) of protocols, with 17% (95% CI: 13-22) in experimental studies. Observations on beneficence varied between 41.17% and 77.38%. Protocol-specific observations ranged between 5.26% and 27.11%, showing regional disparities among study types. RECs must ensure thorough evaluations to uphold autonomy and maximize benefits for participants.

Research Implications: Provide a foundation for future investigations on the work of RECs, the implementation of ethical principles, and equity in research.

Originality/Value: The publication of observations on ethical principles made by the Research Ethics Committees is essential for drafting new research protocols.
Анализ свободных колебаний стержневых систем с помощью метода конечных элементов в усилиях с расширенными функциями формы
Authors: Ngo H.H. , Lalin V.V. , Le T.Q.T. 
Published: September 2024

For free vibration analysis of rod systems formulation of the finite element force method with extended shape functions obtained by using the mode shapes of a fixed-fixed rod is proposed. Examples illustrating the accuracy of numerical solutions for three types of finite elements are given. The use of proposed approach for the space frame gave differences between numerical solutions dealt with 8 finite elements and exact results less than 5% for the first five natural frequencies.
Для анализа свободных колебаний стержневых систем предложена формулировка метода конечных элементов в усилиях с расширенными функциями формы, полученными с использованием форм колебаний неподвижно закрепленного стержня. Приведены примеры, иллюстрирующие точность численного решения для трех типов конечных элементов. Использование предложенного подхода для пространственной рамы дало различия между численными решениями для восьми конечных элементов и точными результатами менее 5% для первых пяти собственных частот.