bluuebunny/crossref_metadata_2025_split huggingface dataset:
ДИСБАЛАНС АДИПОКІНІВ ТА ПОКАЗНИКІВ КЛІТИННОГО ІМУНІТЕТУ В ЩУРІВ З ДІЄТІНДУКОВАНИМ ВІСЦЕРАЛЬНИМ ОЖИРІННЯМ
Authors: Кондро М. М. , Вервега Б. М. , Берегова Т. В. 
Published: October 2024

Вступ. Прогресивне збільшення кількості пацієнтів з ожирінням актуалізувало вивчення порушення функції жирової тканини, яку розглядають не лише як пасивний резервуар для зберігання надлишкового енергетичного субстрату, але як метаболічний активний ендокринний орган, що секретує гормони і цитокіни. Цитокіни й адипокіни жирової тканини беруть участь у регуляції багатьох життєво важливих процесів, дисбаланс яких призводить до розвитку інсулінорезистентності, метаболічного синдрому, цукрового діабету та серцево-судинної патології.
Мета дослідженння – визначити секрецію адипокінів у сироватці крові, жировій тканині та профіль сироваткових цитокінів, оцінити цитоморфологічний стан селезінки у щурів за умов дієтіндукованого ожиріння.
Методи дослідження. Досліди проведено на білих нелінійних щурах-самцях, напрямок включав дослідження механізмів розвитку стеатогепатозу у тварин, які протягом 16 тижнів перебували на висококалорійній дієті (дієта С 11024, Research Dietes, New Brunswick, NJ), найбільш наближеній до можливого характеру харчування осіб з надмірною масою тіла.
Результати й обговорення. У щурів, які впродовж 16 тижнів перебували на висококалорійній дієті з високим вмістом жирів і вуглеводів та зниженим рівнем протеїнів, реєстрували вісцеральне ожиріння без прояву гіперфагії, що супроводжувалось стеатогепатозом. У тварин з дієтіндукованим ожирінням спостерігали зменшення концентрації адипонектину та збільшення вмісту лептину в сироватці крові. Встановлено зростання вмісту лептину в жировій тканині. У щурів, які тривало перебували на висококалорійній дієті, на фоні розвитку вісцерального ожиріння і стеатогепатозу зменшувалися маса селезінки та кількість спленоцитів, що спричиняло дисфункцію імунної системи, одним із проявів якої був дисбаланс вмісту про- і протизапальних цитокінів у сироватці крові.
Висновки. Тривале перебування щурів на висококалорійній дієті зумовлює розвиток вісцерального ожиріння, що характеризується гіпоадипонектинемією (p<0,001) та гіперлептинемією (p<0,01), збільшенням вмісту лептину в жировій тканині (p<0,05). Дисбаланс продукції адипокінів супроводжується зростанням вмісту інтерлейкіну-1β (p<0,01), інтерлейкіну-12 р40 (p<0,001), інтерферону-γ (p<0,05) та зменшенням вмісту інтерлейкіну-4 (p<0,05), інтерлейкіну-10 (p<0,05), трансформуючого фактора росту-β (p<0,01).
A Nearly Similar Powerful Test for Mediation
Authors: van Garderen Kees Jan , van Giersbergen Noud P. A. 
Published: October 2024

Abstract
We derive a new powerful, simple test for mediation. Testing for mediation is empirically important and the no-mediation hypothesis H0:θ1θ2=0 poses a theoretical problem, nonregular at the origin, where standard tests have extremely low rejection probabilities. We prove that a similar test only exists if 1/α∈N. It is unique, but with unfortunate properties. An innovative varying-g method is introduced to derive a nearly similar test, gopt, with power close to the envelope without these undesirable properties, and a second, less similar test, g1.2, with more empirical appeal. Results are illustrated in an educational setting.
Monsoon Winds and Ming Porcelains: Chinese Ceramics and Their Reception in Early Modern South Asia
Authors: Teece Denise-Marie 
Published: October 2024

Abstract
This essay will explore the arrival, acquisition, and reception of Chinese ceramics within early modern South Asia, with a focus on the Mughal dynasty (r. 1526–1857) courtly context. The first step in placing South Asian ceramic collecting practices within the broader historical and geographic circulation of porcelains in the Gulf and Indian Ocean worlds is understanding the breadth and nature of South Asian collections. While the Safavid porcelain collections donated by Shah Abbas to Ardabil, and the massive Chinese porcelain collection of the Ottoman courts held today in Istanbul’s Topkapı Palace are well known and relatively well published, the Chinese ceramic collections of South Asia have received less scholarly attention. Fresh material presented here includes new evidence of the extent of multi-generational Mughal interactions with, and interest in, Chinese ceramics. The broader question to be addressed is how these porcelains were perceived, utilized, and displayed in the South Asian context. Considering textual evidence, contemporary paintings, extant architecture, archaeological finds, and surviving inscribed objects, this essay will argue that Mughal porcelain collections should be understood within the context of their broader collecting activities, and in relation to the porcelain collections and displays of their Timurid ancestors.
Hasht Bihisht: A Spatial Interpretation of the Location, Size, and Layout of Humayun’s Tomb-Garden in the Nizamuddin Area of Mughal Delhi
Authors: Wescoat James L. 
Published: October 2024

Abstract
Humayun’s tomb-garden has many levels of spatial significance that include the garden’s elegant layout, monumental size, and strategic location in the Nizamuddin area of New Delhi. Previous research has shed light on spatial aspects of the tomb’s architecture, visual power, and religio-political symbolism. This article focuses on the garden’s fourfold and ninefold layout, size, and location. It interprets the garden’s hasht bihisht layout through a combination of historical geographic and spatial analysis methods. Conversion of garden measurements to gaz-i Sikandarī (a unit of measurement introduced by Sikandar Lodi [r. 1489–1517], 77.01 cm) units enabled testing hypotheses about garden layout in 5-gaz and 6.5-gaz modules. Topographic analysis sheds light on the garden’s siting in relation to natural landforms, drainage, urbanization, and antecedent architectural sites. Geometrical analysis identifies strong spatial linkages between the tomb-garden, dargāh of the Sufi saint Nizamuddin Awliyaʾ, and grave of Nizamuddin’s poet-disciple Amir Khusraw, with additional connections to antecedent tombs, the city of Dinpanah (Purana Qila), and the Grand Trunk Road from Agra to Delhi. The paper concludes with an interpretation of parallels and connections among Amir Khusraw’s poem Hasht Bihisht, Humayun’s imaginative administrative apparatus, and the hasht bihisht tomb-garden layout.
From the Khan to the Sultan: The Abu’l-Khairid Shāhnāma in the Topkapı Palace Library (H.1488) and Manuscript Production and Presentation under ʿAbdullah bin Iskandar Khan
Authors: Comstock-Skipp Jaimee K. 
Published: October 2024

Abstract
This article examines the sole courtly Shāhnāma of Firdausi to be produced during the Abu’l-Khairid dynasty (commonly called Shaybanid Uzbek, in power 1500–99). It is a lavish—albeit unfinished—copy, and the discussion details the circumstances of its 1564 patronage by the powerful leader ʿAbdullah bin Iskandar Khan (r. 1557–98). Situating the object in the context of Abu’l-Khairid developments in arts and politics during the second half of the sixteenth century, this analysis incorporates the concurrent production of multiple Tīmūr-nāma manuscripts by artisans in Transoxiana. It is posited that the copies of this latter title were made with the intention of conflating Timur’s military conquests with those of ʿAbdullah’s to be the righteous heir of Chinggis Khan. Departing from the 1560s, a final section dwells on the 1590s, during which ʿAbdullah had secured victory and control over the strategic Safavid province of Khurasan. Presented in Istanbul by an embassy arriving from Bukhara, ʿAbdullah’s personal Shāhnāma manuscript was given to the Ottoman sultan Murad III in 1594. This dispatch allows for an examination of the political relations and military coordination between the Ottomans and Abu’l-Khairids, the extent of which are not fully known. These exchanges can, however be gleaned from the Shāhnāma manuscript and the diplomatic circumstances of its transfer.
Large-Scale Surface Air Temperature Bias in Summer over the CONUS and Its Relationship to Tropical Central Pacific Convection in the UFS Prototype 8
Authors: Choi Nakbin , Stan Cristiana 
Published: October 2024

Abstract
This study aims to understand the source of surface air temperature bias over the contiguous United States (CONUS) during boreal summer (June–September) in the Unified Forecast System (UFS) coupled model prototype 8 (P8), developed by the National Centers for Environmental Prediction (NCEP) and the National Oceanic and Atmospheric Administration (NOAA). The focus is on the subseasonal variability defined as a weekly average in weeks 2–5 of forecast leads (total 224 cases; 4 weeks × 2 initialization dates × 4 months × 7 years). The large-scale surface air temperature bias pattern is extracted using the empirical orthogonal function (EOF) analysis. The associated principal component describes the variability of bias for each reforecasting week throughout the 2011–17 reforecasting period. The leading EOF of surface air temperature bias exhibits an east–west dipole pattern over the CONUS, explaining 31.6% of the total variability of weekly temperature bias. This bias pattern is strongly related to the upper-level Rossby wave induced by a bias in convection over the central tropical Pacific. Furthermore, the mean bias of background flow in the extratropics degrades the representation of teleconnections from the tropics to the midlatitudes. UFS P8 has weaker zonal wind over the North Pacific with stronger vertical wind shear than the ERA5 reanalysis. The weak zonal wind hampers the Rossby wave’s propagation, while strong vertical shear reduces its amplitude.
An exploration of factors leading to readiness for organizational health literacy change in community-based health organizations
Authors: Stone Melanie , Wray Ricardo , Rosenfeld Jason , Valerio-Shewmaker Melissa , Wagner Teresa 
Published: October 2024

Introduction Healthcare systems have a responsibility to improve organizational health literacy (OHL) to increase health equity. This study explored two organizational cultural factors, leadership support and staff buy-in, for organizations planning OHL change. Methods Ten community-based health organizations participated in an OHL program. The study design was mixed methods. The qualitative inquiry was interviews with senior leaders to explore awareness of OHL and: impetus to transform, leadership commitment, staff engagement, alignment to organizational goals, and integration of health literacy change with current practices. The quantitative assessment was the Organizational Readiness for Implementing Change (ORIC) questionnaire to assess staff’s perceptions about OHL change readiness. Results Senior leaders articulated the effects of low health literacy in their patient and client population. Support for OHL change was seen at both leadership and staff levels. Impetus for change was primarily a response to a community need or for quality improvement. Most of the non-clinical organizations had higher ORIC scores than the clinical organizations, indicating a perceived higher level of readiness for OHL change. Conclusion Leadership commitment and staff buy-in are important factors of readiness for OHL change. A novel finding is that community-based health organizations are able and willing to engage in OHL change.
Moving in L2 Chinese from childhood to adulthood: Developmental and crosslinguistic factors in bilingual event construal
Authors: Tusun Alimujiang , Wang Yi , Abulajiang Adalaiti 
Published: October 2024

Aims and Objectives/Purpose/Research Questions: The paper examined whether Uyghur-Chinese early successive bilinguals fully acquire motion event construal characteristic of their L2 Chinese, and how factors such as structural overlap between their two languages (i.e., verb-framing) and path type (i.e., presence or absence of boundary crossing) shape the acquisition process. Design/Methodology/Approach: Adopting a developmental approach, we included both child and adult bilinguals within a single design. Participants narrated video clips depicting both boundary-crossing and non-boundary-crossing events (i.e., across vs. up/down). Data and Analysis: The database comprised motion event descriptions of bilinguals representing three age groups (4–6 -year-olds [AG1, no. 48], 8–10 -year-olds [AG2, no. 48], and adult bilinguals [AG3, no. 30]), and Chinese monolinguals (no. 12). Data were analysed in terms of both ‘structural’ (linguistic devices used, and how they were arranged syntactically) and ‘pragmatic’ dimensions of motion expression (how frequently speakers profiled different event components). Findings/Conclusions: Analyses revealed that bilinguals fully established the ‘structural’ aspects of target system at AG2, but the ‘pragmatic’ aspect became target-like at AG3. Structural overlap led to crosslinguistic influence for non-boundary-crossing events while more general effects of path type manifested only at AG1. Originality: The paper enriches current research by featuring a non-Western bilingual community. By focusing on a language pair that is distant genealogically (Turkic vs. Sino-Tibetan) and typologically (agglutinative vs. analytic) but shares key structures in expressing motion, it contributes to a better understanding of the role of structural factors in bilingual event construal. Its developmental approach sheds light on both the process and the product of bilingual language acquisition. Significance/Implications: Our findings confirm that early successive bilinguals can eventually acquire L2-specific patterns of motion construal, but the developmental asymmetry observed between the ‘structural’ and ‘pragmatic’ aspects of motion expression underlines the importance of examining both these aspects for an accurate understanding of bilingual construal of motion events.
Tubulotrabecular adenocarcinoma of the nasopharynx operated by transoral and transpalatal approach in a cat
Authors: Ferenczi Estelle , Ragetly Chantal 
Published: October 2024

Case summary A 10-year-old castrated male crossbreed Birman cat was presented for respiratory difficulties, nasal discharge, dysphagia and wheezing. An obstructive nasopharyngeal mass invading the caudoventral nasal cavity and the left sphenoid sinus was observed on a CT scan. Surgical treatment via a ventral rhinotomy and curettage was performed. Histopathology revealed an adenocarcinoma with tubulotrabecular architecture. The cat’s clinical signs significantly improved postoperatively. After 10 months, a recurrence was documented and a second surgical procedure was performed that allowed the patient to live an additional 6 months without clinical signs and an overall survival time of 19 months after first presentation. Relevance and novel information This case report describes a nasopharyngeal adenocarcinoma treated by ventral rhinotomy in a cat. To our knowledge, there is only one other report describing this surgery on a nasal adenocarcinoma in a cat. The tomodensitometric, endoscopic and unusual histological appearance of the mass are reported. The prognosis after surgical removal of nasal adenocarcinomas in cats is only sparsely documented. This case demonstrates that ventral rhinotomy might be considered if first-line treatment is declined.
Towards a self-applied, mobile-based geolocated exposure therapy software for anxiety disorders: SyMptOMS-ET app
Authors: González-Pérez Alberto , Diaz-Sanahuja Laura , Matey-Sanz Miguel , Osma Jorge , Granell Carlos , Bretón-López Juana , Casteleyn Sven 
Published: October 2024

Objective While exposure therapy (ET) has the potential to help people tolerate intense situation-specific emotions and change avoidance behaviours, no smartphone solution exists to guide the process of in-vivo ET. A geolocation-based smartphone software component was designed and developed to instrumentalize patient guidance in in-vivo ET and its psychological validity was assessed by a group of independent psychology experts. Methods A team of computer scientists and psychologists developed the ET Component for in-vivo ET using geolocation-based technology, following the process-centred design methodology. The ET Component was integrated into the SyMptOMS-ET Android application, which was developed following the co-design methodology. Next, nine independent psychology experts tested and evaluated the ET Component and the SyMptOMS-ET app in the field, following the think-aloud methodology. Participants also completed the Mobile Application Rating Scale (MARS) instrument to quantitatively evaluate the solutions. Results We present the SyMptOMS-ET app’s main features and the ET Component exposure workflow. Next, we discuss the feedback obtained and the results of the MARS instrument. Participants who tested the app were satisfied with the ET Component during exposure scenarios (score of [Formula: see text]4.32 out of 5 [[Formula: see text]0.28] on MARS quality aspects), agreed on the soundness of the theoretical foundations of the solutions developed (score of [Formula: see text]4.57 [[Formula: see text]0.48] on MARS treatment support aspects), and provided minor think-a-loud comments to improve them. Conclusions The results of the expert evaluation demonstrate the psychological validity of the ET Component and the SyMptOMS-ET app. However, further studies are needed to discern the acceptability and efficacy of the mHealth tool in the target population.
10 Years of Communication & Sport: A Review of Theory, Method, and Authorship
Authors: Cummins R. Glenn , Hahn Dustin 
Published: October 2024

Inspired by the regular reflections and suggestions for the future that regularly appear within Communication & Sport, this paper reports the result of a systematic review of a sample of articles from the first 10 vol of the journal to document the most common methods, forms of data employed, theoretical frameworks (and how they are applied), and nationality of author affiliation. Results reflect that the analysis of media texts, either qualitative or quantitative in nature, is the most common methodological approach. Moreover, qualitative approaches dominate the journal. With respect to theories or organizing frameworks, a select few theories appear most frequently, and frameworks related to gender are most common (i.e., hegemonic masculinity, heteronormativity, etc.). Furthermore, most references to theories or framework are just that—mere references. Only a minority of references offered theories as the guiding framework for the articles in which they appeared. To further advance legitimacy of the field, we offer suggestions for expanding the methodological approaches employed within the field, as well as suggestions for the explicit treatment of theory.
Return to Sports after Rotator Cuff Repair
Authors: Marsetio Aldo Fransiskus 
Published: October 2024

Rotator cuff tear (RCT) is one of the most common shoulder disorders in orthopaedic surgery. When conservative treatment fails, arthroscopic rotator cuff repair (RCR) has become the most common procedure to achieve a functional shoulder. Success of rotator cuff repair on athletes is measured by their capability to return to sports (RTS) and return to play (RTP). Most athletes were able to return to the state of preinjury level of play after arthroscopic RCR. Arthroscopic rotator cuff repair has rate of RTS in 75% of patients within an average of 6.4 months. Recreational sports participants was associated with higher rate of RTS, up to more than 90%, even on the patients aged >40 years old. On the contrary, competitive sports and overhead sports athletes were associated with lower rate of RTS. Of all athletes who RTS, only around half of them returned to the equivalent or a higher level of competition. Professional overhead athletes are at higher risk of not returning to their prior level of play. The trends can be observed on performance decline among professional baseball players who underwent RTS. Study on professional football players found no significance difference in RTP rates, performance score, or career longevity between operative and nonoperative group. There are some criteria for RTP after RTS following RCR, namely: time from surgery, pain, range of motion, functional recovery, proprioception, strength and muscular balance, patient perception, psychological readiness, sport-specific training program. Customized rehab protocols for large to massive rotator cuff repairs and patients at increased risk of stiffness should be considered.
Effects of Posterior Tibial Slope on Posterior Cruciate Ligament Injury: A Systematic Review
Authors: Nugroho Johanes Jethro , Konstantino Roy Edward , Anggi Paramitha Dewa Ayu 
Published: October 2024

Introduction and Objective: Posterior cruciate ligament (PCL) injuries occur in an estimated 3% to 37% of all knee injuries. The PCL is the largest and strongest ligament of the knee joint and the primary restraint to posterior tibial translation (PTT) at all flexion angles. Posterior tibial slope (PTS) is an important radiographic measurement defined as the angle between a line perpendicular to the mid-diaphysis of tibia and the posterior inclination of the tibial plateau. Increase of PTS was reported to alter the knee joint kinematics by anteriorly shifting the resting position of tibia and increasing in situ forces on the ACL and counteracts the PTT and reduces force on PCL. In contrast, a decrease of PTS is correlated to significantly higher residual PTT and lower reduction of PTT and increased force on PCL. The literature regarding the effects of decreased PTS on PCL injury is still limited. This study aims to evaluate effects of posterior tibial slope on primary cruciate ligament injury. Material and Method: A comprehensive literature search was conducted in 3 databases, including PubMed, ScienceDirect, and Cochrane Library. Last search was conducted on 17th July 2023. We included prospective and retrospective studies. We presented our results according to PRISMA guidelines. Results: A total of 400 participants from 3 different studies were included in this review. All three studies were retrospective case-control. One study concluded a decrease of PTS was associated with patients with PCL tears. Other studies evaluated further by dividing PTS into lateral PTS and medial PTS. One study found decreased lateral PTS were underlying anatomic risk factors for PCL injury, the other concluded a decreased medial PTS and an increased lateral PTS/medial PTS are associated with increased risk of primary PCL injury. Conclusion: Decrease of PTS is associated with higher risk of PCL injury. Further studies should elaborate and study the effects of PTS including medial PTS and lateral PTS in posterior knee stability.