bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Enigmatic PE/PPE Multigene Family of Mycobacteria and Tuberculosis Vaccination
Authors: Brennan Michael J. 
Published: March 2017

ABSTRACT

The genome of
Mycobacterium tuberculosis
, the bacterium responsible for the disease tuberculosis, contains an unusual family of abundant antigens (PE/PPEs). To date, certain members of this multigene family occur only in mycobacteria that cause disease. It is possible that the numerous proteins encoded by these mycobacterial genes dictate the immune pathogenesis of this bacterial pathogen. There is also evidence that some of these antigens are present at the cell surface and that they affect the pathology and immunology of the organism in many ways. Also, they elicit both antibodies and T cells, they may be involved in antigenic variation, and they may be good candidates for vaccines and drugs. However, since they are plentiful and extremely homologous, these PE/PPEs are very challenging to study, and it is difficult to be certain what role(s) they have in the pathogenesis of tuberculosis. Consequently, how to develop treatments like vaccines using these antigens as candidates is complex.
Pediatric Acute Otitis Media in the Era of Pneumococcal Vaccination
Authors: Tawfik Kareem O. , Ishman Stacey L. , Altaye Mekibib , Meinzen‐Derr Jareen , Choo Daniel I. 
Published: March 2017

Objectives(1) Describe longitudinal trends in annual prevalence of hospital admission for pediatric acute otitis media (AOM) and complications of AOM (CAOM) since introduction of pneumococcal vaccination in 2000 and (2) describe the longitudinal trend of prevalence of hospital admission for pneumococcal meningitis in children with AOM‐related diagnoses in the postvaccination era.Study DesignRetrospective analysis of Kids’ Inpatient Database from 2000 to 2012.SettingCommunity, nonrehabilitation hospitals.Subjects and MethodsTo determine annual prevalence of admission for AOM/CAOM, nationally weighted frequencies of children aged <21 years with acute suppurative otitis media, acute mastoiditis, suppurative labyrinthitis, and/or acute petrositis were collected. The frequency of coexisting pneumococcal meningitis diagnoses among these patients was also collected. Trend analysis of prevalences of admission for AOM/CAOM and for pneumococcal meningitis occurring in the setting of AOM/CAOM from 2000 to 2012 was performed.ResultsBetween 2000 and 2012, annual prevalence of admission for AOM/CAOM decreased from 3.956 to 2.618 per 100,000 persons (P <. 0001) (relative risk reduction 34%). Declines in admission prevalence were most pronounced in children <1 year of age (from 22.647 to 8.715 per 100,000 persons between 2000 and 2012, P <. 0001) and 1 to 2 years of age (from 13.652 to 5.554 per 100,000 persons between 2000 and 2012, P <. 0001). For all ages, the admission prevalence for pneumococcal meningitis and concomitant AOM/CAOM decreased (from 1.760 to 0.717 per 1,000,000 persons, P <. 0001) over the study period.ConclusionsThe prevalence of hospital admission for pediatric AOM/CAOM has declined since the advent of pneumococcal vaccination. Admission rates for pneumococcal meningitis with AOM/CAOM have similarly declined.
Triagem diagnóstica da doença pulmonar obstrutiva crónica
Authors: Talaia Mário , Almeida Catarina 
Published: March 2017

A espirometria é o método aceite para o diagnóstico da DPOC (Doença Pulmonar Obstrutiva Crónica), uma doença com elevados custos sociais. Para determinadas profissões, nomeadamente as que envolvem robustez física, o risco da DPOC pode ser avaliado através de uma espirometria. Neste trabalho, a partir de uma colecção de dados, foi avaliado o tipo de patologia: doença ventilatória obstrutiva e/ou doença ventilatória restritiva. Os resultados mostram que o volume expiratório forçado no 4º segundo deve ser valorizado em substituição da capacidade vital forçada e um novo indicador de triagem foi introduzido a partir do tipo de escoamento. https://doi.org/10.14195/1647-7723_24_12
Intervenção do exército em situações de risco
Authors: Gil António Campos 
Published: March 2017

Numa situação de plena manifestação de risco, ou seja, numa situação de catástrofe, todos os agentes de proteção civil poderão ser envolvidos, em conformidade com as circunstâncias concretas. Ora, sendo as Forças Armadas um dos agentes de proteção civil, de acordo com o quadro legal nacional, também elas dispõem de meios e unidades que disponibilizam em apoio das autoridades competentes. Nestas circunstâncias os meios a empenhar são os concebidos e organizados de acordo com as missões primárias das Forças Armadas e serão utilizados em conformidade com o princípio do duplo uso. No caso particular do Exército serão essencialmente meios operacionais de Apoio de Serviços e de Engenharia Militar os preferencialmente utilizados, podendo contudo, ser utilizados meios e unidades de qualquer tipo da componente operacional, bem como podem ser disponibilizadas infraestruturas da sua componente fixa, ou seja aquartelamentos dos Regimentos localizados no território nacional. https://doi.org/10.14195/1647-7723_24_17
Some Remarks on the Lie Derivative and the Pullback Equation for Contact Forms
Authors: Dacorogna Bernard , Kneuss Olivier , Neves Wladimir 
Published: March 2017

Abstract
Given the contact forms f and g, and the 1-form h, we discuss the existence of a vector field u verifying

ℒ
u

⁢

(
f
)

=

d
⁢

(

u

⁢

⌟

⁢
f

)

+

u

⁢

⌟

⁢
d
⁢
f

=
h

.

${\mathcal{L}_{u}(f\/)=d(u\,\lrcorner\,f\/)+u\,\lrcorner\,df=h.}$

This is closely related to the pullback equation,where we seek for a diffeomorphism φ satisfying

φ
∗

⁢

(
f
)

=
g

.

${\varphi^{\ast}(f\/)=g.}$
FIR/Submm Spectroscopy with Herschel: First Results from the VNGS and H-Atlas Surveys
Authors: Baes Maarten , Fritz Jacopo , Rangwala Naseem , Panuzzo Pasquale , Wilson Christine D. , Eales Steve , Valtchanov Ivan 
Published: March 2017

AbstractThe FIR/submm window is one of the least-studied regions of the electromagnetic spectrum, yet this wavelength range is absolutely crucial for understanding the physical processes and properties of the ISM in galaxies. The advent of the Herschel Space Observatory has opened up the entire FIR/submm window for spectroscopic studies. We present the first FIR/submm spectroscopic results on both nearby and distant galaxies obtained in the frame of two Herschel key programs: the Very Nearby Galaxies Survey and the Herschel ATLAS.
Hydrogen Production via Low Temperature Water Gas Shift Reaction: Kinetic Study, Mathematical Modeling, Simulation and Optimization of Catalytic Fixed Bed Reactor using gPROMS
Authors: Mohammady Maklavany Davood , Shariati Ahmad , Khosravi-Nikou Mohammad Reza , Roozbehani Behrooz 
Published: March 2017

Abstract
The kinetics study, modeling, simulation and optimization of water gas shift reaction were performed in a catalytic fixed bed reactor. The renowned empirical power law rate model was used as rate equation and fitted to experimental data to estimate the kinetics parameters using gPROMS. A good fit between predicted and experimental CO conversion data was obtained. The validity of the kinetic model was then checked by simulation of plug flow reactor which shows a good agreement between experimental and predicted values of the reaction rate. Subsequently, considering axial dispersion, a homogeneous model was developed for simulation of the water-gas shift reactor. The simulation results were also validated by checking the pressure drop of the reactor as well as the mass concentration at equilibrium. Finally, a multi-objective optimization was conducted for water-gas shift reaction in order to maximize hydrogen formation and carbon monoxide conversion, whereas the reactor volume to be minimized. Implementation of optimal controls leads to increase in hydrogen formation at reactor outlet up to 25.55 %.
More than Words: Examining Actions of Power through Extra-verbal Domains in Theological Education
Authors: Cronshaw Darren , Waldron Barnett Elizabeth 
Published: March 2017

AbstractTheological education, in line with mainstream academic culture, has delivered and assessed content primarily through the exchange of words. In turn, ecclesial practice, liturgy, mission, discipleship, and general teaching in the wider church has reflected this heavy verbal (rhetorical and literary) bias. This article reviews the cultural content and power dynamics of our common modes of delivery and assessment in theological education. Exploring the call to justice, inclusion and wholeness as markers of the way of Jesus and as fundamental rubrics for theological communities we will consider: a) Philosophical and pedagogical constructs that inform the intersection of mainstream academic discourse and mainstream theological education; b) Possibilities for explicitly engaging a diversity of age, gender, culture, agency, cognition and ability as normative anthropological samples; c) Resources already present, but somewhat latent, within Christian tradition for engaging non/extra-verbal theology; d) Examples of tasks in theology which educate beyond words.
Hepatic resection for primary and secondary liver malignancies
Authors: Heinrich Stefan , Lang Hauke 
Published: March 2017

AbstractLiver surgery has become the standard treatment of primary liver cancer and liver metastases from colorectal cancer. Also, patients with non-colorectal liver metastases are increasingly offered surgery due to the low morbidity and excellent long-term results. The evolution of two-stage procedures helps to increase resectability. Also, laparoscopic and robotic liver surgery are constantly developed.
Multimodal constructs – multimodal constructions? The role of constructions in the working memory
Authors: Hoffmann Thomas 
Published: March 2017

AbstractLanguage is a symbolic system, whose basic units are arbitrary and conventionalized pairings of form and meaning. In fact, in light of substantive empirical evidence, Construction Grammar approaches advocate the view that not only words but all levels of grammatical description – from morphemes, words, and idioms to abstract phrasal patterns as well as larger discourse patterns – comprise form-meaning pairings, which are collectively referred to as constructions. In this paper, I will discuss the status of multimodal usage-events (multimodal constructs) for the potential entrenchment of multimodal constructions and their implications for human cognition in general. As I will argue, constructionist approaches need to pay more attention to the role of the working memory in assembling and interpreting constructions. Drawing on verbal as well as gesture constructions, I will show that it is essential to distinguish entrenched constructions that are stored in the long-term memory from form-meaning pairings that are assembled in the working memory (online constructions). Once this distinction is made, the precise role of multimodal constructs and the nature of multimodal constructions can finally be disentangled.
Synthesis and evaluation of N,N-di-alkyl-2-methoxyacetamides for the separation of U(VI) and Pu(IV) from nitric acid medium
Authors: Kumaresan R. , Prathibha T. , Robert Selvan B. , Venkatesan K. A. , Antony M. P. 
Published: March 2017

Abstract
The homologs of N,N-di-alkyl-2-methoxyacetamides (DAMeOA) having three different alkyl chains varying from hexyl to decyl (C6, C8 and C10) were synthesized and characterized by NMR and IR spectral analyses. Extraction behavior of U(VI) and Pu(IV) from nitric acid medium in a solution of 0.5 M of DAMeOA in n-dodecane (n-DD) was studied and the results were compared with those obtained using N,N-di-hexyloctanamide (DHOA) in n-dodecane. The effect of various parameters on the distribution ratio of U(VI) and Pu(IV) in DAMeOA was studied. The extraction of nitric acid increased with decrease in chain length of alkyl group attached to amidic nitrogen atom of DAMeOA and the conditional nitric acid extraction constant was determined. The extraction of nitric acid in DAMeOA/n-DD resulted in the formation of third phase in organic phase and the third phase occurred early with DAMeOA having smaller alkyl chain length. In contrast to this, the distribution ratio (D) of U(VI) and Pu(IV) in DAMeOA/n-DD increased with increase in the concentration of nitric acid and with increase in the chain length of alkyl group attached to amidic nitrogen atom of DAMeOA. The stoichiometry of the metal – solvate was determined from the slope of extraction data. Quantitative recovery of uranium and plutonium from the loaded organic phase was achieved using dilute nitric acid.
Spannungsgeregelte Impedanzspektroskopie mit breitbandigen Anregungssignalen für Lithium-Ionen-Zellen in Kfz-Anwendungen
Authors: Haußmann Peter , Melbert Joachim 
Published: March 2017

Zusammenfassung
Die Impedanzspektroskopie für elektrochemische Systeme ist eine etablierte
Methode zur Charakterisierung der elektrochemischen Eigenschaften von
Lithium-Ionen-Zellen. Anhand der frequenzabhängigen Zellimpedanz ist eine
simultane Analyse unterschiedlicher elektrochemischer Prozesse im Zellinneren möglich. Lithium-Ionen-Zellen für Kfz-Anwendungen
weisen typischerweise einen geringen Innenwiderstand im mΩ-Bereich auf. Die Impedanzspektroskopie an derartigen Messobjekten erfordert daher ein angepasstes Verfahren, bei dem die Anregungssignalform und deren technische Realisierung optimal gewählt sind. In diesem Beitrag wird ein Synthesekonzept für breitbandige Anregungssignale vorgestellt. Der Ansatz basiert auf der inversen Fourier-Transformation und dient zur Erzeugung von Signalen mit geringer Auslenkung im Zeitbereich bei gleichzeitig hoher spektraler Anregungsleistung im betrachteten Frequenzbereich. Verfahren der Strom- und Spannungsanregung werden gegenübergestellt, deren jeweilige Vorteile sich in der Quasi-Spannungsanregung kombinieren lassen. Zur Realisierung der Quasi-Spannungsanregung mit beliebigen Spannungszeitverläufen wird eine geregelte Stromanregung eingesetzt. Mit Hilfe einer modellbasierten Simulation wird der Regler für eine Vielzahl unterschiedlicher Messobjekte mit signifikant abweichenden Impedanzeigenschaften dimensioniert und eine allgemeingültige Vorschrift für die Reglerdimensionierung für beliebige Zellen aufgestellt. Die Eigenschaften des neuen Verfahrens werden durch Messungen an Lithium-Ionen-Zellen belegt. So ermittelte Impedanzspektren zeigen gute Übereinstimmung mit etablierten Messverfahren und erreichen hohe Frequenzauflösung und Ergebnisgüte bei deutlich verkürzter Messdauer und geringerem Ladungsdurchsatz.
Hasűri terhesség élő újszülöttel
Authors: Koltai Tamás , Bacskó György 
Published: March 2017

Abstract: Advanced abdominal pregnancy is extremely rare. Symptoms are often nonspecific, and the diagnosis is frequently missed. Maternal mortality and morbidity are also very high especially if the condition is not diagnosed and managed properly. In abdominal pregnancy there is a high incidence of fetal malformations. We are presenting a case of a 38 year old primigravida with an undiagnosed advanced abdominal pregnancy carried beyond 36 weeks of gestation. We delivered a 2090 g baby from the abdomen. A relaparotomy was necessary on the third postoperative day because of abdominal bleeding. At the time of discharge both mother and baby were doing well. The publication also provides a literature overview, including definition, epidemiology, diagnosis and therapy. Orv. Hetil., 2017, 158(13), 508–511.
META-ANALYSIS OF THE RESEARCH OF IL-6 IN PERIPHERAL BLOOD OF PATIENTS WITH INFLUENZA A(H1N1)pdm09
Authors: Shipilov M. V. , Tutelian A. V. 
Published: March 2017

Interleukin-6 (IL-6) is a potent proinflammatory cytokine, which level is increased in the peripheral blood in many infectious diseases, including the flu A(H1N1)pdm09, in some cases (when the excess of his development of immune cells), resulting not only to strengthen the immune system, but also to the development of a “cytokine storm” is characterized by multi-organ failure and often followed by death. To reduce errors, increase the statistical power and increase the reliability of the results according to different researchers, as well as on the results of their own research was conducted a meta-analysis (a quantitative systematic review) of IL-6 studies in peripheral blood of patients with influenza A(H1N1) pdm09. Question: to determine with a high level of confidence, whether IL-6, a marker of the severity and prognosis of the disease. Searches were carried out research work on this subject in a variety of electronic databases (Medline, EMBASE, the Cochrane Controlled Trials Register, and others), reviews, theses, magazines, conference proceedings, and others. In the process of carrying out a meta-analysis of 5 scientific papers were selected that meet the criteria for inclusion/noninclusion in the study (characteristic of scientific papers, diagnostic criteria, age of patients, comparable groups of patients, the presence of self-control, research methodology, statistical criterion and the total number of independent stu dies). Selected studies have shown sufficient uniformity (homogeneity) comparison groups. The results of the meta-analysis are presented in tables, charts and blobogramme, meta-analysis of 5 scientific papers showed that in moderate and severe influenza A(H1N1)pdm09 noted a significant increase in the concentration of IL-6 in peripheral blood of patients compared with the control a group of individuals (healthy). Severe influenza A(H1N1)pdm09 with a high probability of death is characterized by an even greater increase in IL-6 levels (in comparison with the moderate flow) — 11 pg/ml or more. Thus, the results of a meta-analysis of IL-6 with a high degree of probability is defined as a biomarker of disease severity and prognosis of development. At the same time, a result of meta-analysis of observed quite significant changes of the absolute values of the concentration of IL-6 in peripheral blood, which can be explained by using various test patterns and laboratory equipment, so that necessary to accumulate research experience level IL-6 on one and the same test systems and laboratory equipment.
HAZARDS AND RISKS TO CONSUMERS’ HEALTH CAUSED BY POPSICLES ON SALVADOR BEACHES – BAHIA STATE
Authors: Menezes Renata Oliveira dos Santos , Cardoso Ryzia de Cássia Vieira , Guimarães Alaise Gil 
Published: March 2017

Introduction: Beaches are a place for interaction and leisure, as well as a scenery for the provision of services, including the street food trade. In this segment, different workers with different type of foods are included, especially the popsicles. Methods: This study aimed to characterize microbiologically the popsicles commercialized on the beaches of Salvador, Bahia State. A cross-sectional study was carried out on 13 beaches, with the application of semi- structured questionnaires to 33 vendors to characterize microbiologically the popsicles sold on the beaches of Salvador, Bahia State, and the collecting of 198 samples, which were submitted to analysis: counting of Psychrotrophic microorganisms and coagulase-positive staphylococci, estimation of the Most Likely Number of total and thermolerant Coliforms/Escherichia coli and Salmonella spp research. Results: The results showed that in the microbiological profile, most of the samples were in compliance with the standards. However, 34.3% (68) of non-compliance were recorded, including contamination by the various microorganisms studied, except for Salmonella spp., which was not identified. Conclusion: The study identified risks to the costumer's health, given the contamination in the products, for both groups of sellers.
Breaking bad news of cancer diagnosis - the patient’s perspective
Authors: Dhage Amod S. , Wilkinson Anne R. 
Published: March 2017

Background: Communication between physicians and patients is a fundamental aspect of cancer care. Bad news could be defined as "any information, which adversely affects an individual's view of his or her future”. The aim of the research study was to explore the patient’s perspective on receiving cancer news and their expectations regarding the same.Methods: A cross-sectional study was performed in our tertiary care teaching hospital. 50 consenting cancer patients from 18 to 60 years of age were interviewed on the basis of a structured, validated questionnaire.Results: On analysis of the 50 patients ‘answers, it was found that 37 were females and 13 were males, the average age being 50.07 years. The common diagnosis in females was breast cancer (20 patients) and in males it was lung cancer (5 patients). All the patients wanted relatives present with them when the bad news was broken to them. In 66.6% patients, the news was broken by a junior resident, 15% of the doctors didn't greet the patients, 10% of the patients were told the news suddenly, while 99% of the doctors didn’t explain any positive aspects of the disease related to the treatment outcome.Conclusions: This study provides an insight into the expectations of patients from their physicians with regard to the process of breaking bad news.
Superior vena cava obstruction as manifestation of synovial cell sarcoma: a case report and review of literature
Authors: Dhiman Pravesh , Patil C. N. , Raghupathi Renu 
Published: March 2017

Synovial cell sarcomas are one of the most common soft tissue tumors affecting adolescents and young adults. The common location of these tumors is often extremities. Primary involvement of mediastinum is a very rare presentation of this tumor, only few cases have been reported so far. We are reporting the case of a 27-year-old male patient who presented to us with a history of dyspnoea and chest discomfort of one week duration along with features of SVC obstruction. Chest is a frequently involved site of metastasis and lymphomas but rarely involved in synovial sarcoma. The learning point from this case is that rare causes like synovial sarcoma of mediastinum should always be included in differential diagnosis of mediastinal mass and SVC obstruction. We are reporting this case in view of its rarity. Though uncommon this case report emphasizes that synovial cell sarcoma should also be considered in differential diagnosis of mediastinal mass and early recognition with HPE, IHC and prompt institution of treatment can be lifesaving.
Case control study for risk factors associated with oral cancer in central India
Authors: Dhage Dadasaheb , Patil Sonali , Narlwar Uday , Ughade Suresh , Adikane Hemant 
Published: March 2017

Background: Oral cancer is higher prevalent condition in Asian countries. In India, due to higher proportion of population consuming tobacco in either chewing or smoking and alcohol consumption. Methods: Present matched case control study was carried out in regional cancer institute in central India. The study consists of a total 124 cases and 124 controls. Cases were newly diagnosed patients of oral cancer confirmed by histopathological examination. Results: For cases, the mean age (years) was 47.62, the range being 23-83 years while that of controls was 47.89 years, the range being 24-84 years. Majority were males (83.88%). Majority of cases (79.04%) were past chewers who had OR 2.61. Maximum number of cases (19.36%) were past smokers and maximum number of controls (12.09%) were current smokers who had OR 4.54. Maximum number of cases (30.64%) were former drinker and maximum number of controls (8.87%) were current drinker who had OR 2.97. Conclusions: In summary, oral cancer occurs more commonly in middle aged males. The statistical data of this study provide strong evidence that tobacco chewing, smoking and alcohol could be in a straight line responsible for developing oral cancer in central India.