bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in Efficiency and Safety Culture After Integration of an I-PASS–Supported Handoff Process
Authors: Sheth Shreya , McCarthy Elisa , Kipps Alaina K. , Wood Matthew , Roth Stephen J. , Sharek Paul J. , Shin Andrew Y. 
Published: January 2016

BACKGROUND AND OBJECTIVES:
Recent publications have shown improved outcomes associated with resident-to-resident handoff processes. However, the implementation of similar handoff processes for patients moving between units and teams with expansive responsibilities presents unique challenges. We sought to determine the impact of a multidisciplinary standardized handoff process on efficiency, safety culture, and satisfaction.

METHODS:
A prospective improvement initiative to standardize handoffs during patient transitions from the cardiovascular ICU to the acute care unit was implemented in a university-affiliated children’s hospital.

RESULTS:
Time between verbal handoff and patient transfer decreased from baseline (397 ± 167 minutes) to the postintervention period (24 ± 21 minutes) (P &lt; .01). Percentage positive scores for the handoff/transitions domain of a national culture of safety survey improved (39.8% vs 15.2% and 38.8% vs 19.6%; P = .005 and 0.03, respectively). Provider satisfaction improved related to the information conveyed (34% to 41%; P = .03), time to transfer (5% to 34%; P &lt; .01), and overall experience (3% to 24%; P &lt; .01). Family satisfaction improved for several questions, including: "satisfaction with the information conveyed” (42% to 70%; P = .02), “opportunities to ask questions” (46% to 74%; P &lt; .01), and “Acute Care team's knowledgeabout my child’s issues” (50% to 73%; P = .04). No differences in rates of readmission, rapid response team calls, or mortality were observed.

CONCLUSIONS:
Implementation of a multidisciplinary I-PASS–supported handoff process for patients transferring from the cardiovascular ICU to the acute care unit resulted in improved transfer efficiency, safety culture scores, and satisfaction of providers and families.
Reglamentos municipales y ornato público (1851-1912) en Zaragoza: la decoración pictórica de fachadas
Authors: Vázquez Astorga Mónica 
Published: January 2016

Este texto tiene como finalidad analizar el compromiso del consistorio municipal zaragozano con el ornato público a través de las disposiciones dictadas en sus reglamentos entre 1851 y 1912, y, de manera concreta, con la decoración pictórica de las fachadas de sus inmuebles privados como medida de embellecimiento y ennoblecimiento urbanos. Asimismo, la cuestión del color en la arquitectura era en estos momentos un tema de actualidad debido al debate suscitado en Europa con motivo de la interpretación de los vestigios de ornamentación pictórica encontrados en la arquitectura de la antigua Grecia.
Value models: Finance, risk, and political economy
Authors: Christophers Brett 
Published: January 2016

AbstractThis article develops a basic typological framework for understanding and analyzing financial risk from a political economy perspective. It is motivated by growing awareness of the contemporary significance of financial risk and by the fact that the political-economic literature on such risk currently lacks a workable heuristic. The framework distinguishes between and fleshes out what I refer to as the principal ‘value models’ of finance: fees, gains, premia, and spreads. Its primary aim is to facilitate the identification and conceptualization of: (1) the different risk configurations characterizing the heterogeneous political economy of finance; and (2) the different ways in which key stakeholders — such as finance capital, non-financial capital, and labor — come to be enrolled in such configurations. It also aims to contribute to the wider project of demystifying not just financial risk in particular but modern finance more generally.
The significant impact of framing coils on long-term outcomes in endovascular coiling for intracranial aneurysms: how to select an appropriate framing coil
Authors: Ishida Wataru , Sato Masayuki , Amano Tatsuo , Matsumaru Yuji 
Published: January 2016

OBJECTIVE
The importance of a framing coil (FC)—the first coil inserted into an aneurysm during endovascular coiling, also called a lead coil or a first coil—is recognized, but its impact on long-term outcomes, including recanalization and retreatment, is not well established. The purposes of this study were to test the hypothesis that the FC is a significant factor for aneurysmal recurrence and to provide some insights on appropriate FC selection.

METHODS
The authors retrospectively reviewed endovascular coiling for 280 unruptured intracranial aneurysms and gathered data on age, sex, aneurysm location, aneurysm morphology, maximal size, neck width, adjunctive techniques, recanalization, retreatment, follow-up periods, total volume packing density (VPD), volume packing density of the FC, and framing coil percentage (FCP; the percentage of FC volume in total coil volume) to clarify the associated factors for aneurysmal recurrence.

RESULTS
Of 236 aneurysms included in this study, 33 (14.0%) had recanalization, and 18 (7.6%) needed retreatment during a mean follow-up period of 37.7 ± 16.1 months. In multivariate analysis, aneurysm size (odds ratio [OR] = 1.29, p < 0.001), FCP < 32% (OR 3.54, p = 0.009), and VPD < 25% (OR 2.96, p = 0.015) were significantly associated with recanalization, while aneurysm size (OR 1.25, p < 0.001) and FCP < 32% (OR 6.91, p = 0.017) were significant predictors of retreatment. VPD as a continuous value or VPD with any cutoff value could not predict retreatment with statistical significance in multivariate analysis.

CONCLUSIONS
FCP, which is equal to the FC volume as a percentage of the total coil volume and is unaffected by the morphology of the aneurysm or the measurement error in aneurysm length, width, or height, is a novel predictor of recanalization and retreatment and is more significantly predictive of retreatment than VPD. To select FCs large enough to meet the condition of FCP ≥ 32% is a potential relevant factor for better long-term outcomes. These findings support our hypothesis that the FC is a significant factor for aneurysmal recurrence.
The effect of increased T2 signal intensity in the spinal cord on the injury severity and early neurological recovery in patients with central cord syndrome
Authors: Schroeder Gregory D. , Hjelm Nik , Vaccaro Alexander R. , Weinstein Michael S. , Kepler Christopher K. 
Published: January 2016

OBJECTIVE
The aim of this paper was to compare the severity of the initial neurological injury as well as the early changes in the American Spinal Injury Association (ASIA) motor score (AMS) between central cord syndrome (CCS) patients with and without an increased T2 signal intensity in their spinal cord.

METHODS
Patients with CCS were identified and stratified based on the presence of increased T2 signal intensity in their spinal cord. The severity of the initial neurological injury and the progression of the neurological injury over the 1st week were measured according to the patient's AMS. The effect of age, sex, congenital stenosis, surgery within 24 hours, and surgery in the initial hospitalization on the change in AMS was determined using an analysis of variance.

RESULTS
Patients with increased signal intensity had a more severe initial neurological injury (AMS 57.6 vs 75.3, respectively, p = 0.01). However, the change in AMS over the 1st week was less severe in patients with an increase in T2 signal intensity (−0.85 vs −4.3, p = 0.07). Analysis of variance did not find that age, sex, Injury Severity Score, congenital stenosis, surgery within 24 hours, or surgery during the initial hospitalization affected the change in AMS.

CONCLUSIONS
The neurological injury is different between patients with and without an increased T2 signal intensity. Patients with an increased T2 signal intensity are likely to have a more severe initial neurological deficit but will have relatively minimal early neurological deterioration. Comparatively, patients without an increase in the T2 signal intensity will likely have a less severe initial injury but can expect to have a slight decline in neurological function in the 1st week.
Geographic variation in climate as a proxy for climate change: Forecasting evolutionary trajectories from species differentiation and genetic correlations
Authors: Schneider Heather E. , Mazer Susan J. 
Published: January 2016

PREMISE OF THE STUDY:Climate change models for California predict a warmer, drier future, potentially resulting in shorter growing seasons. If phenotypic differences between closely related species currently distributed across a moisture and temperature gradient represent adaptations to their abiotic environment, then as conditions become warmer and drier, populations presently adapted to cooler and wetter conditions may evolve to become more similar to those adapted to warmer and drier conditions. Two sister species, Clarkia unguiculata and C. exilis, are distributed across a moisture and temperature gradient in the southern Sierra Nevada, providing an opportunity to predict how this process may occur.METHODS:In a greenhouse experiment using wild‐collected seeds from 11 populations in the southern Sierra Nevada, we examined relationships among elevation, climatic conditions, and population means for each trait, then evaluated bivariate relationships among maternal family means, using raw values and controlling for population and seed mass effects on phenotype.KEY RESULTS:Clarkia exilis occupied warmer, drier conditions, typically at lower elevations, than C. unguiculata did and flowered earlier and faster, producing smaller flowers with lower herkogamy. In C. unguiculata, petal area, herkogamy, and the rate of flower production were positively correlated with days to first flower.CONCLUSIONS:If selection favors earlier flowering, smaller petals, or faster flower production in C. unguiculata, then the genetic correlations among these traits should reinforce their joint evolution. Moreover, the correlations between these traits and herkogamy may promote the evolution of self‐fertilization as an indirect response to selection, a previously unrecognized potential outcome of climate change.
BLACK HOLE MERGERS AND BLUE STRAGGLERS FROM HIERARCHICAL TRIPLES FORMED IN GLOBULAR CLUSTERS
Authors: Antonini Fabio , Chatterjee Sourav , Rodriguez Carl L. , Morscher Meagan , Pattabiraman Bharath , Kalogera Vicky , Rasio Frederic A. 
Published: January 2016

ABSTRACT
Hierarchical triple-star systems are expected to form frequently via close binary–binary encounters in the dense cores of globular clusters (GCs). In a sufficiently inclined triple, gravitational interactions between the inner and outer binary can cause large-amplitude oscillations in the eccentricity of the inner orbit (“Lidov–Kozai (LK) cycles”), which can lead to a collision and merger of the two inner components. In this paper we use Monte Carlo models of dense star clusters to identify all triple systems formed dynamically and we compute their evolution using a highly accurate three-body integrator which incorporates relativistic and tidal effects. We find that a large fraction of these triples evolve through a non-secular dynamical phase which can drive the inner binary to higher eccentricities than predicted by the standard secular perturbation theory (even including octupole-order terms). We place constraints on the importance of LK-induced mergers for producing: (i) gravitational wave sources detectable by Advanced LIGO (aLIGO), for triples with an inner pair of stellar black holes (BHs); and (ii) blue straggler stars, for triples with main-sequence-star components. We find a realistic aLIGO detection rate of BH mergers due to the LK mechanism of ∼1 yr−1, with about 20% of these having a finite eccentricity when they first chirp into the aLIGO frequency band. While rare, these events are likely to dominate among eccentric compact object inspirals that are potentially detectable by aLIGO. For blue stragglers, we find that the LK mechanism can contribute up to ∼10% of their total numbers in GCs.
Des clusters aux écosystèmes industriels locaux
Authors: Torre André , Zimmermann Jean-Benoît 
Published: January 2016

Depuis plusieurs décennies, chercheurs et décideurs sont quasi-unanimes pour considérer le développement local et les systèmes productifs territoriaux comme des allant-de-soi. Certaines notions ont même joué un rôle phare de la pensée et de l’action : districts, SPL, milieux, clusters, technopoles, pôles de compétitivité… Comprendre les enjeux contemporains des rapports entre industrie et territoire nécessite de prendre en compte les évolutions qui se sont dessinées au fil du temps, autour de ces questions de systèmes locaux et de leur insertion dans les dynamiques globales de changement des économies. Notre démarche vise à problématiser et illustrer la manière dont les systèmes industriels localisés, aujourd’hui le plus souvent dénommés « clusters », au-delà des aspects d’interactions locales et globales entre les acteurs, se doivent d’internaliser toujours davantage des dimensions contextuelles de proximité, aussi bien environnementales que sociétales. L’adjonction de ces deux variables conduit à déborder de plus en plus largement du cadre traditionnel et des frontières des mondes de l’industrie et de l’innovation technologique, pour renouveler l’approche des systèmes locaux, vers les questions de systèmes d’affaires ou d’écologie industrielle et territoriale.
Récents enseignements de la théorie des réseaux en faveur de la politique et du management des clusters
Authors: Suire Raphaël , Vicente Jérôme 
Published: January 2016

À la suite d’une abondante littérature sur le rôle important du développement des clusters pour l’innovation et la croissance dans les économies fondées sur la connaissance, les politiques de cluster ont été récemment et de façon croissante remises en cause par les évidences empiriques. Le but de l’article est de montrer qu’en dépit de ce scepticisme croissant, de nouvelles opportunités pour les politiques de soutien aux clusters et leur management collectif existent. Ces opportunités requièrent de passer de la logique du « tout réseau » qui caractérise les « cluster policy guidelines » à des formes plus chirurgicales et ciblées d’incitation à la collaboration dans la R&D, ainsi qu’à des dispositifs renouvelés de coordination, favorisant un ensemble de propriétés structurelles des réseaux le long des phases du cycle de vie des clusters.
Le déploiement des écosystèmes industriels et d’innovation dans le business vert
Authors: Depret Marc-Hubert , Hamdouch Abdelillah 
Published: January 2016

Les technologies vertes constituent aujourd’hui un secteur en plein essor. Cependant, leur déploiement est confronté à de multiples obstacles. Dans ce contexte, les politiques publiques et la capacité des acteurs à faire émerger et à structurer des écosystèmes « verts » sont cruciales. Après une caractérisation générale de ce que recouvre le business vert, l’article souligne le rôle décisif des conditions institutionnelles et des politiques publiques dans les dynamiques d’émergence, de structuration et de performance de ces écosystèmes. Il insiste également sur l’importance des logiques stratégiques des acteurs et de leur capacité à se connecter à des réseaux globaux d’innovation et de valorisation et à s’inscrire d’emblée dans une perspective de marchés mondiaux.
Arrangements institutionnels et écologie industrielle
Authors: Decouzon Cyril , Maillefert Muriel , Petit Olivier , Sarran Alice 
Published: January 2016

Les démarches d’écologie industrielle visent à mutualiser des ressources ou à économiser des flux de matière ou d’énergie. Elles concernent à la fois les entreprises et les territoires. L’objet de cet article est d’analyser l’architecture des formes organisationnelles des synergies de mutualisation liées à la gestion des déchets mis en place. L’analyse des divers outils de coordination (contrats, chartes, etc.) issue de plusieurs cas d’étude montre qu’il existe une architecture institutionnelle régulière dont la logique relève des formes hybrides au sens d’O. Williamson. Le contrat apparaît ainsi à la fois comme un outil de coordination et un outil de gouvernance. Néanmoins, les seuls critères transactionnels se révèlent insuffisants pour différencier les formes organisationnelles et doivent être complétés par une analyse de l’action collective et de ses formes.
Posttranscriptional and Translational Control of Gene Regulation in CD4+ T Cell Subsets
Authors: Istomine Roman , Pavey Nils , Piccirillo Ciriaco A. 
Published: January 2016

Abstract
The immune system is under strict regulatory control to ensure homeostasis of inflammatory responses, lying dormant when not needed but quick to act when called upon. Small changes in gene expression can lead to drastic changes in lineage commitment, cellular function, and immunity. Conventional assessment of these changes centered on the analysis of mRNA levels through a variety of methodologies, including microarrays. However, mRNA synthesis does not always correlate directly to protein synthesis and downstream functional activity. Work conducted in recent years has begun to shed light on the various posttranscriptional changes that occur in response to a dynamic external environment that a given cell type encounters. We provide a critical review of key posttranscriptional mechanisms (i.e., microRNA) and translational mechanisms of regulation of gene expression in the immune system, with a particular emphasis on these regulatory processes in various CD4+ T cell subsets.
Phenotypic detection and molecular characterization of beta-lactamase genes among Citrobacter species in a tertiary care hospital
Authors: Praharaj Ashok Kumar , Khajuria Atul , Kumar Mahadevan , Grover Naveen 
Published: January 2016

Abstract
Objective: To examine the distribution, emergence, and spread of genes encoding beta-lactamase resistance in Citrobacter species isolated from hospitalized patients in a tertiary care hospital. Methods: A prospective study was conducted in a 1000-bed tertiary care center in Pune, India from October 2010 to October 2013. A total of 221 Citrobacter spp. isolates were recovered from clinical specimens from different patients (one isolate per patient) admitted to the surgical ward, medical ward and medical and surgical Intensive Care Units. Polymerase chain reaction (PCR) assays and sequencing were used to determine the presence of beta-lactamase encoding genes. Conjugation experiments were performed to determine their transferability. Isolate relatedness were determined by repetitive element based-PCR, enterobacterial repetitive intergenic consensus-PCR and randomly amplified polymorphic DNA. Results: Among 221 tested isolates of Citrobacter spp. recovered from various clinical specimens, 179 (80.9%) isolates showed minimum inhibitory concentration (MIC) >4 μg/ml against meropenem and imipenem. One hundred and forty-five isolates with increased MICs value against carbapenems were further processed for molecular characterization of beta-lactamase genes. Susceptibility profiling of the isolates indicated that 100% retained susceptibility to colistin. Conjugation experiments indicated that blaNDM-1was transferable via a plasmid. Conclusion: The ease of NDM-1 plasmid transmissibility may help their dissemination among the Citrobacter species as well as to others in Enterobacteriaceae. Early detection, antimicrobial stewardship and adequate infection control measures will help in limiting the spread of these organisms.
Analytic hierarchy process as module for productivity evaluation and decision-making of the operation theater
Authors: Ezzat Abdelrahman E. M. , Hamoud Hesham S 
Published: January 2016

AbstractThe analytic hierarchy process (AHP) is a theory of measurement through pairwise comparisons and relies on the judgments of experts to derive priority scales, these scales that measure intangibles in relative terms. The aim of the article was to develop a model for productivity measurement of the operation theater (OT), which could be applied as a model for quality improvement and decision-making. AHP is used in this article to evolve such a model. The steps consist of identifying the critical success factors for measuring the productivity of OT, identifying subfactors that infl auence the critical factors, comparing the pairwise, deriving their relative importance and ratings, and calculating the cumulative effect according to the attributes in OT. The cumulative productivitycan be calculated by the end and can be compared Ideal productivity to measure the productive of OT in percentage fraction. Hence, the productivity could be calculated. Hence, AHP is a very useful model to measure the productivity in OT.
Tirofiban as Treatment for Acute Retinal Artery Occlusion following Internal Carotid Artery Flow Diverter Implantation
Authors: Pierro Luisa , La Spina Carlo , Corvi Federico , Cicinelli Maria V. , Scomazzoni Francesco , Cappelletti Alberto , Bandello Francesco 
Published: January 2016

Purpose To report a favorable outcome of branch retinal artery occlusion (BRAO) treated by means of early administration of tirofiban, a glycoprotein IIb-IIIa platelet receptor inhibitor. Methods Case report. Results A 65-year-old woman developed dramatic visual impairment in her left eye secondary to BRAO after left internal carotid artery endovascular reconstruction with flow diverter stent implant; visual acuity was hand motion. A dose of intravenous tirofiban was injected 10 minutes after symptoms onset. Fourteen hours after drug infusion, retinal fluorescein angiography revealed a well-perfused macula with a partial reperfusion of the inferior temporal branch of the central retinal artery; visual acuity was 20/20 in both eyes. Conclusions This case supports the effectiveness of tirofiban in secondary BRAO in neurosurgery and may open its usage to further research.
Editor's Notes
Authors: Dooly Melinda 
Published: January 2016

As the year draws to an end, we offer you a variety of articles for the holiday season. This issue’s featured author is Evelyn Arizpe (Glasgow University) and we also have an interview with Jazone Cenoz from the University of the Basque Country, accompanied by our regular research articles, all very relevant to current topics in the teaching and learning of language and literature.
An interview with Dr. Jasone Cenoz on multilingual education and translanguaging
Authors: Hernández-Castillo Núria 
Published: January 2016

Dr. Jasone Cenoz is Professor of Applied Linguistics in the Department of Research Methods at the University of the Basque Country. Her research interests include multilingual education, the acquisition of English as a third language, language learning in school contexts and minority languages. The interview published in this issue was conducted in the autumn of 2015 as part of the meetings held with regard to the author’s doctoral thesis and research interests during a brief stay in Donostia (Spain).