bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socioeconomic disparities in income, education and geographic location for hypertension among Thai adults: Results from the National Socioeconomic Survey
Authors: Singsalasang Atthawit , Laohasiriwong Wongsa , Puttanapong Nattapong , Phajan Teerasak , Boonyaleephan Suwanna 
Published: October 2017

Background: Hypertension (HT) has been one of the leading global risk factors for health and the leading cause of death in Thailand for decades. The influence of socioeconomic factors on HT has been varied and inconclusive. The aim of this study was to determine the association between socioeconomic determinants and HT in Thailand. Methods: This study used data from the National Socioeconomic Survey, a cross-sectional study that was conducted by the National Statistical Office of Thailand in the years 2005, 2006 and 2007. In our analysis, data were collected on gender, age, marital status, smoking status, education, status of work, occupation, current liability (short-term debt), household monthly income, residential area, region and previously diagnosed HT by a physician. Results: The odds of having HT were significantly higher among those who had household monthly income, education, residential area and region. The participants who had monthly income of <10001 baht (2005: AOR = 3.19, 95%CI:1.47 - 6.92; 2006: AOR 2.53, 95%CI:1.37 - 4.69; 2007: AOR = 3.35, 95%CI: 1.97 - 7.00), were living in Bangkok compared with the Northeast region (2005: AOR = 1.72, 95%CI:1.37 - 2.17; 2006: AOR = 2.44, 95%CI: 1.89 - 3.13; 2007: AOR = 2.63, 95%CI 2.08 - 3.45), lived as an urban resident (2005: AOR= 1.32, 95%CI: 1.12 - 1.56; 2006: AOR= 1.21, 95%CI: 1.02 - 1.43; 2007: AOR= 1.47, 95%CI: 1.18 - 1.62), and finished primary education (2005: AOR =1.21, 95%CI: 1.03 - 1.43; 2006: AOR= 1.23, 95%CI: 1.04 - 1.46; 2007: AOR= 1.18, 95%CI: 1.01 - 1.38) when controlling for other covariates. Conclusion: This study indicated that socioeconomic disparity has an influence on HT. Those with low educational attainment, low income, lived in urban regions, and were metropolitan residents (Bangkok) were vulnerable to HT.
Nutritional and micronutrient status of adolescent schoolgirls in eastern Sudan: A cross-sectional study
Authors: Mahgoub Hyder M. , Fadlelseed Omar E. , Khamis Ammar H. , Bilal Jalal A. , Adam Ishag 
Published: October 2017

Background: Adolescents, especially girls, are susceptible to malnutrition and their diet must be adequate to support their very rapid growth and development. Currently, there is little published data on the nutritional state amongst adolescent girls in Sudan. Methods: A cross sectional study was conducted to assess the nutritional and micronutrient status of adolescent schoolgirls in eastern Sudan during the period of January-February 2015. Weight and height were measured using standard methods. Haemoglobin and ferritin levels were measured using blood samples, and blood films for malaria and stool samples for Schistosoma mansoni were investigated. Nutritional status was assessed according to the WHO 2006 reference values. Copper and zinc concentrations were measured by atomic absorption. Results: Twenty-five (13.7%) out of 183 girls were stunted. Seventy (38.3%) were thin; 17.5, 9.3 and 11.5% had mild, moderate and severe thinness, respectively. Only 10 (5.5%) and six (3.3%) girls were overweight and obese, respectively. The prevalence of anaemia was 77.0%. While there was no significant difference in the haemoglobin, ferritin, copper levels and thinness; thin children had significantly lower zinc (P=0.007). Conclusions: There is a high rate of stunting, thinness and anaemia among adolescent schoolgirls in eastern Sudan. More care has to be taken in order to provide a better nutrition status in the area.
A Concise Tool for Measuring Care Coordination from the Provider's Perspective in the Hospital Setting
Authors: Weston Christine M. , Yune Sehyo , Bass Eric B. , Berkowitz Scott A. , Brotman Daniel J. , Deutschendorf Amy , Howell Eric E. , Richardson Melissa B. , Sylvester Carol , Wu Albert W. 
Published: October 2017

BACKGROUNDTo support hospital efforts to improve coordination of care, a tool is needed to evaluate care coordination from the perspective of inpatient healthcare professionals.OBJECTIVESTo develop a concise tool for assessing care coordination in hospital units from the perspective of healthcare professionals, and to assess the performance of the tool in measuring dimensions of care coordination in 2 hospitals after implementation of a care coordination initiative.METHODSWe developed a survey consisting of 12 specific items and 1 global item to measure provider perceptions of care coordination across a variety of domains, including teamwork and communication, handoffs, transitions, and patient engagement. The questionnaire was distributed online between October 2015 and January 2016 to nurses, physicians, social workers, case managers, and other professionals in 2 tertiary care hospitals.RESULTSA total of 841 inpatient care professionals completed the survey (response rate = 56.6%). Among respondents, 590 (75%) were nurses and 37 (4.7%) were physicians. Exploratory factor analysis revealed 4 subscales: (1) Teamwork, (2) Patient Engagement, (3) Handoffs, and (4) Transitions (Cronbach's alpha 0.84‐0.90). Scores were fairly consistent for 3 subscales but were lower for patient engagement. There were minor differences in scores by profession, department, and hospital.CONCLUSIONThe new tool measures 4 important aspects of inpatient care coordination with evidence for internal consistency and construct validity, indicating that the tool can be used in monitoring, evaluating, and planning care coordination activities in hospital settings.
Optimizing the Profitability and Quality of Service in Carshare Systems Under Demand Uncertainty
Authors: Lu Mengshi , Chen Zhihao , Shen Siqian 
Published: October 2017

Carsharing has been considered as an effective means to increase mobility and reduce personal vehicle usage and related carbon emissions. In this paper, we consider problems of allocating a carshare fleet to service zones under uncertain one-way and round-trip rental demand. We employ a two-stage stochastic integer programming model, in the first stage of which we allocate shared vehicle fleet and purchase parking lots or permits in reservation-based or free-floating systems. In the second stage, we generate a finite set of samples to represent demand uncertainty and construct a spatial–temporal network for each sample to model vehicle movement and the corresponding rental revenue, operating cost, and penalties from unserved demand. We minimize the expected total costs minus profit and develop branch-and-cut algorithms with mixed-integer, rounding-enhanced Benders cuts, which can significantly improve computation efficiency when implemented in parallel computing. We apply our model to a data set of Zipcar in the Boston–Cambridge, Massachusetts, area to demonstrate the efficacy of our approaches and draw insights on carshare management. Our results show that exogenously given one-way demand can increase carshare profitability under given one-way and round-trip price differences and vehicle relocation cost whereas endogenously generated one-way demand as a result of pricing and strategic customer behavior may decrease carshare profitability. Our model can also be applied in a rolling-horizon framework to deliver optimized vehicle relocation decisions and achieve significant improvement over an intuitive fleet-rebalancing policy. The online appendix is available at https://doi.org/10.1287/msom.2017.0644 .
Deactivated CRISPR Associated Protein 9 for Minor-Allele Enrichment in Cell-Free DNA
Authors: Aalipour Amin , Dudley Jonathan C , Park Seung-min , Murty Surya , Chabon Jacob J , Boyle Evan A , Diehn Maximilian , Gambhir Sanjiv S 
Published: October 2017

Abstract

BACKGROUND
Cell-free DNA (cfDNA) diagnostics are emerging as a new paradigm of disease monitoring and therapy management. The clinical utility of these diagnostics is relatively limited by a low signal-to-noise ratio, such as with low allele frequency (AF) mutations in cancer. While enriching for rare alleles to increase their AF before sample analysis is one strategy that can greatly improve detection capability, current methods are limited in their generalizability, ease of use, and applicability to point mutations.

METHODS
Leveraging the robust single-base-pair specificity and generalizability of the CRISPR associated protein 9 (Cas9) system, we developed a deactivated Cas9 (dCas9)-based method of minor-allele enrichment capable of efficient single-target and multiplexed enrichment. The dCas9 protein was complexed with single guide RNAs targeted to mutations of interest and incubated with cfDNA samples containing mutant strands at low abundance. Mutation-bound dCas9 complexes were isolated, dissociated, and the captured DNA purified for downstream use.

RESULTS
Targeting the 3 most common epidermal growth factor receptor mutations (exon 19 deletion, T790M, L858R) found in non-small cell lung cancer (NSCLC), we achieved &gt;20-fold increases in AF and detected mutations by use of qPCR at an AF of 0.1%. In a cohort of 18 NSCLC patient-derived cfDNA samples, our method enabled detection of 8 out of 13 mutations that were otherwise undetected by qPCR.

CONCLUSIONS
The dCas9 method provides an important application of the CRISPR/Cas9 system outside the realm of genome editing and can provide a step forward for the detection capability of cfDNA diagnostics.
Reflection of Barbie Culture on the games of children in the context of gender<p>Barbie kültürünün toplumsal cinsiyet bağlamında çocuk oyunlarına yansımaları
Authors: Ördek İnceoğlu Seval , Aktaş Arnas Yaşare 
Published: October 2017

There are many studies conducted about Barbie dolls. However, it has not been investigated how these toys reflected on gender perceptions of children. That is this topic is still an issue of concern. On the other hand, games give crucial clues regarding making sense of children’s worlds. Through this study, it was aimed to analyze the reflections of Barbie culture on children’s dramatic game processes. The design of the study was case study one of qualitative research designs aiming to obtain information in depth. The participants consisted of seven children in 5-year class of a nursery school and prefer to play in dramatic game center during game time. The data of the study was collected by observations. Within data collection, the whole process was recorded as videos in order to minimize data loss. In total, video record of 280 minutes was obtained. The data was analyzed by content analysis method. It was found out that children frequently emphasized physical features playing with Barbies, besides they involved in gendered conversations. Moreover, it was revealed that Barbie culture increased the gendered utterances of children when handled in terms of gender. Our study is parallel to the results of limited number of studies regarding this matter.Extended English abstract is in the end of PDF (TURKISH) file.ÖzetBarbie bebeklere ilişkin olarak yapılmış bir çok araştırma bulunmaktadır. Ancak bu oyuncakların çocukların toplumsal cinsiyet algılarına nasıl yansıdıkları yeterince araştırılmamıştır. Yani bu konu halen merak konusudur. Oyunlar ise çocukların dünyalarının anlaşılmasında önemli ipuçları sunarlar. Bu çalışmada Barbie kültürünün çocukların dramatik oyun süreçlerine yansımalarının incelenmesi amaçlanmıştır. Araştırmanın yöntemini derinlemesine bilgi edinilmesini amaçlayan nitel araştırma yöntemlerinden durum çalışması oluşturmaktadır. Araştırmanın çalışma grubunu bir anaokulundaki 5 yaş sınıfına devam eden ve oyun zamanında dramatik oyun merkezinde oynamayı tercih eden yedi çocuk oluşturmuştur. Çalışmada veriler gözlemler yoluyla elde edilmiştir. Veri toplama sürecinde, veri kaybını en aza indirmek için sürecin tamamı kamera kaydına alınmıştır. Toplamda yaklaşık 280 dakikalık kamera kaydı elde edilmiştir. Veriler içerik analizi yöntemiyle analiz edilmiştir. Araştırmada çocukların Barbie’lerle oynadıkları sırada sıkça fiziksel özelliklere vurgu yaptıkları, ayrıca cinsiyetçi söylemlerde bulundukları belirlenmiştir. Ayrıca «toplumsal cinsiyet» bakımından ele alındığında Barbie kültürünün çocukların cinsiyetçi söylemlerini beslediği sonucuna ulaşılmıştır. Araştırmamız konuya ilişkin olarak yapılmış sınırlı sayıdaki çalışmanın sonuçlarıyla örtüşmektedir.
The molecular identification of Calodium hepaticum in the wild brown rat (Rattus norvegicus) in Poland
Authors: Buńkowska-Gawlik Katarzyna , Perec-Matysiak Agnieszka , Burzyńska Klaudia , Hildebrand Joanna 
Published: October 2017

Abstractis a parasitic nematode found primarily in rodents but known to infect numerous other mammal species, and causing in humans the hepatic calodiasis. Herein, we present the first finding of
Natural occurrence of microsporidia infecting Lepidoptera in Bulgaria
Authors: Pilarska Daniela , Takov Danail , Hyliš Miroslav , Radek Renate , Fiala Ivan , Solter Leellen , Linde Andreas 
Published: October 2017

AbstractWe examined 34 lepidopteran species belonging to 12 families to determine presence and prevalence of microsporidian pathogens. The insects were collected from May 2009 to July 2012 from 44 sites in Bulgaria.
On the number of maximal independent sets in complete q-ary trees
Authors: Taletskiy Dmitriy S. , Malyshev Dmitriy S. 
Published: October 2017

Abstract
The paper is concerned with the asymptotic behaviour of the number mi(T

q,n
) of maximal independent sets in a complete q-ary tree of height n. For some constants α
2 and β
2 the asymptotic formula mi(T
2,n
)∼ α
2⋅ (β
2)2
n

is shown to hold as n → ∞. It is also proved that

mi
⁡
(

T

q
,
3
k

)
∼

α
q

(
1
)

⋅
(

β
q

)

q

3
k

,
mi
⁡
(

T

q
,
3
k
+
1

)
∼

α
q

(
2
)

⋅
(

β
q

)

q

3
k
+
1

,
mi
⁡
(

T

q
,
3
k
+
2

)
∼

α
q

(
3
)

⋅
(

β
q

)

q

3
k
+
2

$\begin{array}{}
\operatorname{mi}(T_{q,3k})\thicksim \alpha^{(1)}_q\cdot(\beta_q)^{q^{3k}},\operatorname{mi}(T_{q,3k+1})\thicksim \alpha^{(2)}_q\cdot(\beta_q)^{q^{3k+1}},\operatorname{mi}(T_{q,3k+2})\thicksim \alpha^{(3)}_q\cdot(\beta_q)^{q^{3k+2}}
\end{array} $

as k→ ∞ for any sufficiently large q, some three pairwise distinct constants

α
q

(
1
)

,

α
q

(
2
)

,

α
q

(
3
)

$\begin{array}{}
\alpha^{(1)}_q,\alpha^{(2)}_q,\alpha^{(3)}_q
\end{array} $

and a constant bq
.
Limit theorems for the logarithm of the order of a randomA-mapping
Authors: Yakymiv Arsen L. 
Published: October 2017

AbstractLet 𝔖nbe a semigroup of mappings of a setXwithnelements into itself,Abe some fixed subset of the setNof natural numbers, andVn(A) be a set of mappings from 𝔖n, with lengths of cycles belonging toA. The mappings fromVn(A) are calledA-mappings. We suppose that the setAhas an asymptotic densityϱ> 0, and that |k:k≤n,k∈A,m−k∈A|/n→ϱ2asn→ ∞ uniformly overm∈ [n,Cn] for each constantC> 1. A numberM(α) of different elements in a set {α,α2,α3, …} is called an order of mappingα∈ 𝔖n. Consider a random mappingσ=σn(A) having uniform distribution onVn(A). In the present paper it is shown that random variable lnM(σn(A)) is asymptotically normal with meanl(n)=∑k∈A(n)ln⁡(k)/k$l(n)=\sum_{k\in A(\sqrt{n})}\ln(k)/{k}$and varianceϱln3(n)/24, whereA(t) = {k:k∈A,k≤t},t> 0. For the caseA=Nthis result was proved by B. Harris in 1973.
Application of the reduced I-V Blaesser’s characteristics in predicting PV modules and cells conversion efficiency in medium and high insolation conditions
Authors: Rodziewicz Tadeusz , Rajfur Małgorzata , Wacławek Maria 
Published: October 2017

Abstract
The article presents theoretical foundations of application of the reduced I-V Blaesser’s characteristics in predicting a photovoltaic cell/module (PV) efficiency, together with calculation procedures. A detailed analysis of the error of this transformation method of characteristics was carried out. Its practical application in predicting efficiency of operation of various PV cells and modules in medium and high insulation conditions was demonstrated. The practical suitability of the presented method in early detection of ageing phenomena, such as, for example, absorber degradation taking place in PV modules, was demonstrated. The article was prepared on the basis of the results of testing five different PV modules with various constructions, made of different materials and absorbers, such as: c-Si, mc-Si, CIS, a-Si_SJ, a-Si_TJ. The used measurement data were collected during the 16-year period of the experimental PV modules testing system operation in Opole University, equipped with a data acquisition system.
Impact of thermal treatment of mixtures of sewage sludge and plant material on selected chemical properties and Vibrio fischeri response
Authors: Gondek Krzysztof , Baran Agnieszka , Mierzwa-Hersztek Monika , Kopeć Michał 
Published: October 2017

Abstract
The aim of the research was to evaluate the effect of temperature during the treatment process as well as the effect of adding plant materials to sewage sludge on selected chemical properties and Vibrio fischeri response. The mixtures were placed in a chamber furnace, under airless conditions. Two temperature procedures were applied: 300 and 600ºC; the exposure time in both cases was 15 minutes. Thermal treatment of sewage sludge without a plant component is not well-founded and may cause an increase in concentration of trace elements. Using the temperature of 300ºC caused significantly lower changes in the contents of total forms of trace elements than using the temperature of 600ºC. The metals extracted from the studied mixtures were not toxic for the Vibrio fischeri. In the case of the fractional composition of humic compounds, thermal treatment of mixtures of sewage sludge and plant materials is not beneficial in terms of labile fractions, but it had a beneficial effect on stabilizing the durable bonds between C compounds in those mixtures.
The Effect of Inorganic or Organic Zinc on the Morphology of the Intestine in Broiler Chickens
Authors: Levkut M. , Fukasová M. , Bobíková K. , Levkutová M. , Čobanová K. , Levkut M. 
Published: October 2017

Abstract
This study compared the effect of dietary supplementation with an inorganic or organic zinc source on the gut morphology in the jejunum of broilers. One-day-old chickens were fed a basal diet (Control group: BD — 32 mg Zn.kg−1 DM), or the same BD supplemented with 30 mg or 70 mg of Zn per kg of DM in the form of ZnSO4.H2O (Group 1: 30 mg ZnSO4; Group 2: 70 mg ZnSO4), and 30 mg or 70 mg of Zn per kg of DM in the form of zinc chelate of glycine hydrate (Group 3: 30 mg Zn-Gly; Group 4: 70 mg Zn-Gly) for 40 days. The villus height was increased in the groups which received 30 mg ZnSO4 and 70 mg ZnSO4 and or 70 mg ZnSO4, as compared to the BD and 30 mg Zn-Gly. The villus surface was higher in all groups receiving the Zn supplements in comparison to the BD.
The Incidence of Hepatitis E Virus in Domestic Pigs
Authors: Jackova A. , Mandelik R. , Novotny J. , Salamunova S. , Vilcek S. 
Published: October 2017

Abstract
Hepatitis E virus (HEV) is the causative agent of hepatitis E — an emerging zoonotic disease distributed worldwide. The aim of this study was to determine the prevalence of HEV in Slovakian domestic pigs, as this has not been studied yet. Clinical samples (n = 269) from fourteen randomly selected domestic pig farms for three different age categories of pigs were analysed and the subsequently detected isolates were genetically characterized. The reverse transcriptase polymerase chain reaction (RT-PCR) analysis revealed that 32 pigs (11.9 %) of all age categories were HEV RNA positive. The highest occurrence was detected in fattening pigs (14.8 %) and the lowest in weaning pigs (12.5 %). The HEV RNA was not observed at all in the youngest category (the suckling piglets). The phylogenetic analysis revealed that all Slovak HEV isolates clustered into two genetic groups of the genotype HEV-3.
Resolution CM/Res(2016)2 and Centralised Intra Venous Additive Services (CIVAS): Challenges and Opportunities
Authors: Vrignaud Sandy 
Published: October 2017

AbstractThe aim of the European Council’s Resolution CM/res(2016)2 on good reconstitution practices in health care establishments for medicinal products for parenteral use is to guide the health care establishment’s decision as to where reconstitution should take place: in the pharmacy or the clinical area. Injectable preparation in hospital pharmacy is performed in Centralised Intra Venous Additive Services (CIVAS). Nevertheless, challenges such as ensuring the sterility of the preparation, the physicochemical stability of the product, and process validation for instance should be taken into account. This opinion paper examines the challenges, impacts, and responsibilities for pharmacists, nurses, and hospital management related to implementing the resolution, regarding the experience of countries where CIVAS are already implemented. It also discusses the opportunities of implementing CIVAS with regard to patient care safety and potential financial savings.
Urban Geomorphology in Coastal Environment: Man-Made Morphological Changes in a Seaside Tourist Resort (Rapallo, Eastern Liguria, Italy)
Authors: Brandolini Pierluigi , Faccini Francesco , Paliaga Guido , Piana Pietro 
Published: October 2017

Abstract
This research focuses on the reconstruction of the morphological modifications of the coastal floodplain of Rapallo (Eastern Liguria, NW Italy) due to human intervention since the eighteenth century. By the second half of the nineteenth century Rapallo became a popular tourist destination: as a consequence, the urban development of the floodplain started and became very intense after Second World War, strongly modifying former landforms.
The study was carried out using multi-temporal cartographic and photographic comparison, the analysis of geo-thematic cartography and documentation from the Basin Master Plan and the town plan of Rapallo, the interpretation of cores from regional database and field data from direct urban surveys. Man-made landforms were mapped and classified using the new geomorphological legend which is in progress in the framework of the Working Groups on “Cartography” and “Urban Geomorphology” of the Italian Association of Physical Geography and Geomorphology (AIGEO).
The main significant morphological changes were stream diversions and channeling, excavations and filling, quarry activities, embankments along the shoreline and overurbanization. Human interventions, in addition to local geomorphological and climate features, increased flood hazard and risk, which historically affected the city of Rapallo.
Small Farmers in Four Southeast European Countries. A Qualitative Analysis of Life Strategies in Twenty-Five Agricultural Households
Authors: Krstić Nemanja , Derado Augustin , Naterer Andrej , Kumalić Ismet 
Published: October 2017

Abstract
This paper brings an extended Bourdieusian theoretical framework to the analysis of the life strategies of small farmers in four SEE societies (Serbia, Bosnia-Herzegovina, Croatia, and Slovenia). Practices and strategies of farming households are situated in two partially overlapping fields, the formal economy and the informal economy. The paper is based on a qualitative analysis of twenty-five interviewed households. It covers the structural conditions of the households’ participation in both fields of ‘play’, an analysis of household capital (economic-agricultural, social and cultural) and an interpretation of practice (i.e. the strategy dimension). The framework is extended to include an exploration of the households’ reflexivity and agency. The findings suggest that various structural limitations impede the households from developing successful practices in the formal field (unless the households have exceptional levels of agency), and that the most common life strategy is food self-provisioning, along with reliance on practices in the informal field enabled by social capital.