bluuebunny/crossref_metadata_2025_split huggingface dataset:
Continuity From Prelinguistic Communication to Later Language Ability: A Follow-Up Study From Infancy to Early School Age
Authors: Määttä Sira , Laakso Marja-Leena , Ahonen Timo , Tolvanen Asko , Westerholm Jari , Aro Tuija 
Published: October 2016

Purpose
This longitudinal study examined the development of prelinguistic skills and the continuity of communication and language from the prelinguistic stage to school age.

Method

Prelinguistic communication of 427 Finnish children was followed repeatedly from 6 to 18 months of age (
n
= 203–322 at ages 6, 9, 12, 15, and 18 months), and its associations with language ability at ages 2;0 (
n
= 104), 3;0 (
n
= 112), 4;7 (
n
= 253), 5;3 (
n
= 102), and 7;9 (
n
= 236) were examined using latent growth curve modeling.

Results
Prelinguistic development across several skills emerged as a rather stable intraindividual characteristic during the first 2 years of life. Continuity from prelinguistic development to later language ability was indicated. The common level and growth of prelinguistic skills were significant predictors of language ability between ages 2;0 (years;months) and 7;9; the percentage explained varied between 10.5% and 53.3%. A slow pace of development across multiple skills, in particular, led to weaker language skills.

Conclusions
The results support (a) the idea of a developmental continuum from prelinguistic to linguistic ability and (b) the dimensional view of language ability by indicating that individual variations in early communication skills show consistency that extends beyond the toddler years. Our results also advocate developmental surveillance of early communication by emphasizing the significance of growth in predicting language development.

Supplemental Material

https://doi.org/10.23641/asha.14963937
Dipole modes with depressed amplitudes in red giants are mixed modes
Authors: Mosser B. , Belkacem K. , Pinçon C. , Takata M. , Vrard M. , Barban C. , Goupil M.-J. , Kallinger T. , Samadi R. 
Published: October 2016

Context. Seismic observations with the space-borne Kepler mission have shown that a number of evolved stars exhibit low-amplitude dipole modes, which is referred to as depressed modes. Recently, these low amplitudes have been attributed to the presence of a strong magnetic field in the stellar core of those stars. Subsequently, and based on this scenario, the prevalence of high magnetic fields in evolved stars has been inferred. It should be noted, however, that this conclusion remains indirect.
Aims. We intend to study the properties of mode depression in evolved stars, which is a necessary condition before reaching conclusions about the physical nature of the mechanism responsible for the reduction of the dipole mode amplitudes.
Methods. We perform a thorough characterization of the global seismic parameters of depressed dipole modes and show that these modes have a mixed character. The observation of stars showing dipole mixed modes that are depressed is especially useful for deriving model-independent conclusions on the dipole mode damping. We use a simple model to explain how mode visibilities are connected to the extra damping seen in depressed modes.
Results. Observations prove that depressed dipole modes in red giants are not pure pressure modes but mixed modes. This result, observed in more than 90% of the bright stars (mV ≤ 11), invalidates the hypothesis that depressed dipole modes result from the suppression of the oscillation in the radiative core of the stars. Observations also show that, except for visibility, seismic properties of the stars with depressed modes are equivalent to those of normal stars. The measurement of the extra damping that is responsible for the reduction of mode amplitudes, without any prior on its physical nature, potentially provides an efficient tool for elucidating the mechanism responsible for the mode depression.
Conclusions. The mixed nature of the depressed modes in red giants and their unperturbed global seismic parameters carry strong constraints on the physical mechanism responsible for the damping of the oscillation in the core. This mechanism is able to damp the oscillation in the core but cannot fully suppress it. Moreover, it cannot modify the radiative cavity probed by the gravity component of the mixed modes. The recent mechanism involving high magnetic fields proposed for explaining depressed modes is not compliant with the observations and cannot be used to infer the strength and prevalence of high magnetic fields in red giants.
Endovascular Neurosurgery in the Northern Macro- region of Rio Grande do Sul: Part I
Authors: Vanzin José , Azambuja Jr Nério , Frighetto Leonardo , Frohlich Alan , Varela Daniel , Mesquita Filho Paulo , Roman Alex , Manzato Luciano 
Published: October 2016

Introduction The city of Passo Fundo, in the north of the Rio Grande do Sul state, has been standing out in the health care field for many years. The state has become a reference in endovascular interventional neuroradiology. We will cover 10 years of experience in this area and divide our observations in 3 parts: cerebral angiograms (part I), carotid angioplasties (part II) and intracranial aneurysms (part III). The goal of part I is to statistically assess the cerebral angiograms, their indications, risks and complications, as well as to do a technical review.
Materials and Methods A retrospective study from 2005 to 2015 with a total of 5,567 interventional neuroradiology procedures performed. A total of 4,114 angiograms, 639 embolizations of intracranial aneurysms, 414 carotid angioplasties, 143 embolizations of cerebral arteriovenous malformations, 32 embolizations of dural arteriovenous fistulas, 102 cerebral vasospasm treatments, 21 treatments of epistaxis, 36 embolizations of craniocervical tumor, 25 thrombolysis of ischemic stroke, 18 vertebroplasties and 13 embolizations of arteriovenous malformations of the face.
Results A total of 4,084 procedures performed, 21,811 vessels studied, average vase 7.62/2.82 vessel and patient/procedure. Of these, 2,536 were diagnostic procedures and 1,548 angiographic controls. Of the total, 1,188 patients received only an angiogram, 27.14% of which were therapeutic procedures. We obtained a total of 3.89% complications: 2.33% reflection vasovagal, 0.56% allergic skin reaction, anaphylactic shock 0.07%, 0.27% femoral hematoma, 0.26% transient neurological deficit, 0.12% permanent neurological deficit and no case of death.
Conclusion Cerebral angiography in adults, children and infants is a safe procedure with low risk of permanent neurological complications.
Factors Associated with Knee Stiffness following Surgical Management of Multiligament Knee Injuries
Authors: Westermann Robert , Cook Shane , Glass Natalie , Amendola Ned , Wolf Brian , Bollier Matthew , Hanley Jessica 
Published: October 2016

AbstractPostoperative knee stiffness can influence outcomes following operative treatment of multiligament knee injuries (MLKIs). The purpose of this study was to evaluate patient and surgical factors that may potentially contribute to stiffness following surgery for MLKIs. All surgically managed MLKIs involving two or more ligaments over a 10-year period at a single level one trauma center were included in this study. A retrospective review was performed to gather objective data related to the development of knee stiffness after surgery. Patients were classified as “stiff” postoperatively if they (1) had a flexion contracture greater than 10 degrees, (2) failed to reach 120 degrees of flexion at final follow-up, or (3) underwent a manipulation under anesthesia with or without arthroscopic lysis of adhesions to improve range of motion. Patient and surgical factors were evaluated systematically to determine factors associated with stiffness. The mean age of the cohort was 27.6 years at the time of surgery and mean follow-up was 50 weeks. Overall, 26/121 (21.5%) knees were diagnosed with postoperative stiffness. In the acute postoperative phase, 17 patients underwent manipulation under anesthesia. There were no significant differences in age, body mass index, associated injuries, mechanism, external fixation use or surgical timing (acute vs. chronic) between stiff and normal knees. Factors associated with the development of postoperative stiffness included knee dislocation (p = 0.04) and surgical intervention on three or more ligaments (p = 0.04). Careful attention to postoperative rehabilitation regimens should be given to patients with knee dislocations and/or those undergoing reconstruction or repair of three or more injured ligaments. Surgeons may utilize spanning external fixation if necessary without increasing the rate of long-term stiffness. Further, acute surgery does not appear to influence rates of postoperative stiffness or the need for manipulation.
Zehn Jahre Qualitätsmanagement: Wahrnehmung und Stellenwert aus Sicht von Hausärzten in einem Ärztenetz
Authors: Kühlein T. , Madlo-Thiess F. , Wambach V. , Schaffer S. 
Published: October 2016

Zusammenfassung
Hintergrund: Vor 10 Jahren wurde Qualitätsmanagement (QM) für den ambulanten Sektor verpflichtend eingeführt.
Ziel der Arbeit: Wir wollten wissen, wie die Einführung von QM von Hausärzten erlebt wurde, welchen Stellenwert es heute für sie hat und wie sie die Zukunft von QM einschätzen.
Material und Methoden: In einem qualitativen Studiendesign wurden Ärzte eines Ärztenetzes in Experteninterviews anhand eines semistrukturierten Interviewleitfadens befragt. Die verschriftlichten Interviews wurden in einem zunächst induktiven, dann deduktiven Prozess in Triangulation kodiert. In einem Diskussions- und Einigungsprozess konnten Themenfelder und Kodefamilien identifiziert werden. Die Befragung endete nach Informationssättigung.
Ergebnisse: Für die Standardisierung einiger Basisprozesse wie Hygiene bestand Einverständnis. QM ließe sich jedoch kaum auf einen Bereich übertragen, der wesentlich von zwischenmenschlicher Beziehung und Kommunikation geprägt sei. Die Ärzte gaben an, QM auf ein erträgliches und für sie sinnvolles Maß reduziert zu haben. Zertifizierung wurde weiterestgehend abgelehnt. Die Erwartungen für die nächsten 10 Jahre waren im Sinne immer mehr bürokratischer Vorgaben eher pessimistisch.
Schlussfolgerung: Die gesetzliche Einführung von QM war ein Eingriff der Gesellschaft in den professionellen Bereich der Ärzte. Statt passivem Widerstand und Beschränkung von QM auf ein erträgliches Minimum könnte eine engagierte eigenständige Qualitätsarbeit helfen, gesellschaftliches Vertrauen zurückzugewinnen, um die notwendige professionelle Autonomie zu erhalten.
Ergebnisse strukturierter Fokusgruppenarbeit zur Professionalisierung des zahnärztlichen Gutachterwesens in Deutschland
Authors: Brauer H. , Walther W. , Dick M. 
Published: October 2016

Zusammenfassung
Hintergrund: Im Mittelpunkt der professionellen Selbstkontrolle steht in der Medizin das Gutachterwesen. Um im zahnärztlichen Gutachterwesen einen gezielten Entwicklungsimpuls zu setzen, wurde eine Reflexion aus der Perspektive der Gutachter initiiert.
Methodik: 5 Gruppendiskussionen zum Thema „Professionalisierung des zahnärztlichen Gutachterwesens“ wurden mit 32 erfahrenen Gutachtern als Diskutanten durchgeführt und mittels qualitativer Inhaltsanalyse ausgewertet.
Ergebnisse: Die Auswertung ergab einen Katalog mit 68 Ideen, welche in 15 Kategorien eingeteilt wurden. Diskutierte Lösungsansätze waren z. B. Gutachter-Qualitätszirkel, kollegialer/interprofessioneller Austausch, Supervision bei Neugutachtern und Feedback für Gutachter/Zahnärzte.
Schlussfolgerung: Mehr Reflexivität trägt zu einer Verbesserung des Gutachterwesens sowie zur Qualitätssicherung bei der Begutachtung bei.
Errata: Selbstmanagementförderung bei chronischer Krankheit für Menschen mit Migrationshintergrund – ein Gruppenkurs mit Peer-Ansatz als Beitrag zu gesundheitlicher Chancengerechtigkeit
Authors: Zanoni S. , Gabriel E. , Salis Gross C. , Deppeler M. , Haslbeck J. 
Published: October 2016

Erratum
Zanoni S, Gabriel E, Salis Gross C, Deppeler M, Haslbeck J. Selbstmanagementförderung bei chronischer Krankheit für Menschen mit Migrationshintergrund – ein Gruppenkurs mit Peer-Ansatz als Beitrag zu gesundheitlicher Chancengerechtigkeit. Gesundheitswesen 2016;
Bei diesem Beitrag wurde der engl. Titel korrigiert. Korrekt ist: Chronic Disease Self-management Support for People with a Migrant Background:
towards a Peer-led Group Program to Improve Equity in Health
Lability of secondary organic particulate matter
Authors: Liu Pengfei , Li Yong Jie , Wang Yan , Gilles Mary K. , Zaveri Rahul A. , Bertram Allan K. , Martin Scot T. 
Published: October 2016

Significance
Mass lability of atmospheric organic particulate matter, meaning its tendency to evaporate, is an important property in the mechanisms governing the climate and health effects. This property can be governed by both the volatility and the molecular diffusivity of the constituent organic species. An experimental approach presented herein highlights a nonlabile-to-labile transition at a threshold humidity for material representative of anthropogenic particulate matter. The behavior differs markedly from materials representing biogenic sources, which lack such a transition. Accounting for this transition in the interpretation of laboratory datasets collected at low relative humidity can potentially reduce discrepancies between modeled and observed concentrations of particulate matter in urban regions.
Horizontal gene transfer is more frequent with increased heterotrophy and contributes to parasite adaptation
Authors: Yang Zhenzhen , Zhang Yeting , Wafula Eric K. , Honaas Loren A. , Ralph Paula E. , Jones Sam , Clarke Christopher R. , Liu Siming , Su Chun , Zhang Huiting , Altman Naomi S. , Schuster Stephan C. , Timko Michael P. , Yoder John I. , Westwood James H. , dePamphilis Claude W. 
Published: October 2016

Significance
Horizontal gene transfer (HGT) is the nonsexual transfer and genomic integration of genetic materials between organisms. In eukaryotes, HGT appears rare, but parasitic plants may be exceptions, as haustorial feeding connections between parasites and their hosts provide intimate cellular contacts that could facilitate DNA transfer between unrelated species. Through analysis of genome-scale data, we identified >50 expressed and likely functional HGT events in one family of parasitic plants. HGT reflected parasite preferences for different host plants and was much more frequent in plants with increasing parasitic dependency. HGT was strongly biased toward expression and protein types likely to contribute to haustorial function, suggesting that functional HGT of host genes may play an important role in adaptive evolution of parasites.
Synthetically derived bat influenza A-like viruses reveal a cell type- but not species-specific tropism
Authors: Moreira Étori Aguiar , Locher Samira , Kolesnikova Larissa , Bolte Hardin , Aydillo Teresa , García-Sastre Adolfo , Schwemmle Martin , Zimmer Gert 
Published: October 2016

Significance
Since the discovery of bat influenza A-like genomic sequences (provisionally designated HL17NL10 and HL18NL11), it was uncertain whether these sequences encode infectious viruses and, if so, which cells might support propagation of these viruses. Using chimeric vesicular stomatitis virus (VSV) encoding HL18 or HL17, a particular cell line of canine origin was found to be highly susceptible to infection. Taking advantage of this cell line, we succeeded to generate recombinant HL17NL10 and HL18NL11. These viruses revealed marked differences to conventional influenza A viruses because they do not use the same receptor, in addition to initiating infection from the basolateral site of polarized epithelial cells. The established reverse genetic system will undoubtedly help characterizing these hitherto uncultivable viruses.
Herbivore teeth predict climatic limits in Kenyan ecosystems
Authors: Žliobaitė Indrė , Rinne Janne , Tóth Anikó B. , Mechenich Michael , Liu Liping , Behrensmeyer Anna K. , Fortelius Mikael 
Published: October 2016

Significance
The living conditions of plant-eating mammals can be modeled by reverse-engineering the functional shapes of their teeth. Here we introduced and tested a scoring scheme for describing functional properties of large mammalian herbivore teeth to capture their relationship to environmental conditions. We found that minimum Net Primary Productivity is the environmental variable best predicted by dental traits. These findings refine and provide direct biological context to previously reported results, where traits were found to predict overall climate rather than limiting conditions. We propose that nonavailability of the preferred plant foods (e.g., during dry seasons or longer dry periods), rather than the properties of average foods consumed, is the main functional link between climate and herbivore teeth.
Structure of the mitochondrial ATP synthase from
Pichia angusta
determined by electron cryo-microscopy
Authors: Vinothkumar Kutti R. , Montgomery Martin G. , Liu Sidong , Walker John E. 
Published: October 2016

Significance
Living cells need fuel in the form of adenosine triphosphate, or ATP, to stay alive. This fuel is generated by a molecular machine made of two motors joined by a rotor. One generates rotation by using energy provided by oxidative metabolism or photosynthesis; the other uses energy transmitted by the rotor to make ATP molecules from its building blocks, adenosine diphosphate, or ADP, and inorganic phosphate. The structure has been determined of a fungal machine, isolated from its cellular power stations, the mitochondria, where the machine operates. It provides unsuspected details of the blueprint of the machine and how it works. The working principles of the fungal machine apply to similar machines in all species.
The savings problem in the original position: assessing and revising a model
Authors: Brandstedt Eric 
Published: October 2016

AbstractThe common conception of justice as reciprocity seemingly is inapplicable to relations between non-overlapping generations. This is a challenge also to John Rawls’s theory of justice as fairness. This text responds to this by way of reinterpreting and developing Rawls’s theory. First, by examining the original position as a model, some revisions of it are shown to be wanting. Second, by drawing on the methodology of constructivism, an alternative solution is proposed: an amendment to the primary goods named ‘sustainability of values’. This revised original position lends support to intergenerational justice as fairness.
The isoflavone fraction from soybean presents mRNA maturation inhibition activity
Authors: Kurata Masashi , Murata Yuki , Momma Keiko , Fouad Ali Mursi Intisar , Takahashi Masakazu , Miyamae Yusaku , Kambe Taiho , Nagao Masaya , Narita Hiroshi , Shibuya Yasuyuki , Masuda Seiji 
Published: October 2016

Abstract
Recent findings indicate that mRNA splicing inhibitors can be potential anticancer candidates. We have previously established a screening system which monitors mRNA processing in order to identify mRNA processing inhibitors. Among a number of dietary resources, isoflavone fractions showed an inhibitory effect of mRNA processing. These findings demonstrate that a variety of dietary sources have an impact on mRNA biogenesis.
InMoDe: tools for learning and visualizing intra-motif dependencies of DNA binding sites
Authors: Eggeling Ralf , Grosse Ivo , Grau Jan 
Published: October 2016

Abstract

Summary
Recent studies have shown that the traditional position weight matrix model is often insufficient for modeling transcription factor binding sites, as intra-motif dependencies play a significant role for an accurate description of binding motifs. Here, we present the Java application InMoDe, a collection of tools for learning, leveraging and visualizing such dependencies of putative higher order. The distinguishing feature of InMoDe is a robust model selection from a class of parsimonious models, taking into account dependencies only if justified by the data while choosing for simplicity otherwise.

Availability and Implementation
InMoDe is implemented in Java and is available as command line application, as application with a graphical user-interface, and as an integration into Galaxy on the project website at http://www.jstacs.de/index.php/InMoDe.
Flares, wind and nebulae: the 2015 December mini-outburst of V404 Cygni
Authors: Mu noz-Darias T. , Casares J. , Mata Sánchez D. , Fender R. P. , Armas Padilla M. , Mooley K. , Hardy L. , Charles P. A. , Ponti G. , Motta S. E. , Dhillon V. S. , Gandhi P. , Jiménez Ibarra F. , Butterley T. , Carey S. , Grainge K. J. B. , Hickish J. , Littlefair S. P. , Perrott Y. C. , Razavi-Ghods N. , Rumsey C. , Scaife A. M. M. , Scott P. F. , Titterington D. J. , Wilson R. W. 
Published: October 2016

Abstract
After more than 26 years in quiescence, the black hole transient V404 Cyg went into a luminous outburst in June 2015, and additional activity was detected in late December of the same year. Here, we present an optical spectroscopic follow-up of the December mini-outburst, together with X-ray, optical and radio monitoring that spanned more than a month. Strong flares with gradually increasing intensity are detected in the three spectral ranges during the ∼10 days following the Swift trigger. Our optical spectra reveal the presence of a fast outflowing wind, as implied by the detection of a P-Cyg profile (He i–5876 Å) with a terminal velocity of ∼ 2500 km s−1 . Nebular-like spectra – with an Hα equivalent width of ∼500 Å – are also observed. All these features are similar to those seen during the main June 2015 outburst. Thus, the fast optical wind simultaneous with the radio jet is most likely present in every V404 Cyg outburst. Finally, we report on the detection of a strong radio flare in late January 2016, when X-ray and optical monitoring had stopped due to Sun constraints.
Factors Affecting Speech Perception Improvement Post Implantation in Congenitally Deaf Adults
Authors: O’Gara Suzanne J. , Cullington Helen E. , Grasmeder Mary L. , Adamou Maria , Matthews Emily S. 
Published: October 2016

Objectives:To identify factors preimplantation associated with postimplantation speech perception improvement in the adult congenitally deaf population.Design:Forty-four adult cochlear implant (CI) patients who had a severe to profound hearing loss from birth were identified from this centre’s database. Eight preimplantation factors, speech intelligibility, preimplantation hearing levels, communication mode, preimplantation speech perception scores, progression of hearing loss, age at implantation, hearing aid use preimplantation, and gender, were recorded during the CI assessment process. These factors were investigated to determine their effect on speech perception improvement postimplantation. The outcome measures were the improvement in scores for the BKB Sentence test and CUNY Sentence test with lipreading after implantation. In the final analysis, 26 patients were included in the CUNY analysis, and 30 patients were included in the BKB analysis.Results:Speech intelligibility rating, preimplantation hearing levels, and communication mode were shown to be significantly associated with improvements in speech perception postimplantation.Conclusion:Three factors were identified that affected speech perception improvement postimplantation: speech intelligibility, preimplantation hearing levels, and communication mode. These factors can be used to counsel CI patients regarding potential speech perception improvements from cochlear implantation, although these are based on average data and may not reflect individual performance.