bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heel pressures with generic and focused rigid heel cast devices while in a static supine and seated position
Authors: Marshall J. , Branthwaithe H. , Chockalingam N. 
Published: June 2016

Objective: To identify if the choice of material used to make focused rigid cast (FRC) and generic heel cups has an effect on heel pressure in healthy individuals during a static supine and seated position. Method: A repeated measure design was used to compare the effect of two focused rigidity heel devices made from different materials (3M semi-rigid and Benecast FLEX) and a generic polymer gel heel cup device on barefoot heel pressures. Subjects had heel pressures taken while barefoot and with the three different heel devices while in a supine and seated position using the device. Results: We recruited 32 healthy participants (21 females, and 11 males). When comparing Benecast FLEX and 3M semi-rigid focused rigidity casts with barefoot and the generic heel cups significant reductions in pressures were seen in all areas while seated and in the distal area while supine. However, there was no statistical difference between the two FRC devices, or between barefoot and the generic heel cup in either position. Conclusion: This study demonstrates that FRC heel devices effectively reduced heel pressures in healthy individuals and therefore could be used in practice when a reduction in pressure is required for the management of heel pressure ulcers in bedbound or chair-bound patients. Declaration of interest: Materials were supplied from Benecare Medical (who agreed to supply 20 rolls of Benecast FLEX), and the podiatry department of Kent Community Health NHS Trust (who agreed to supply some of the materials).
Meeting in the same space: Encountering, making and performing archive in Siobhan Davies Dance Table of Contents
Authors: Krische Rachel 
Published: June 2016

Abstract
This article will reflect on the experience of the collaborative process of making and performing Table Of Contents (2013–2014), produced by Siobhan Davies Dance. It follows Professor Sarah Whatley’s article for this journal, ‘Digital inscriptions and the dancing body: Expanding territories through and with the archive’ (Choreographic Practices, 5:1), and seeks to further examine and expand notions of archive from a position within a research, making and performance project. Running alongside the main text are blocks of questions generated within the research and creation process. The origins of these were collectively expressed in extensive conversations by the artistic team and then further processed and translated into my own working notebooks. The references included in this article have been selected because they often acted as a spur/provocation to the thought processes underpinning many of the creative decisions at the time of making. Later in the article, I will focus on one specific making methodology out of the five that I undertook within the project, in order to offer an example of how I addressed the area of archive within the investigation.
Implementation of Microfluidic Chip Electrophoresis for the Detection of B-cell Clonality
Authors: Vazan M , Kasubova I , Vanochova A , Lukac P , Plank L , Lasabova Z 
Published: June 2016

Abstract

Introduction: A clonal population of B-cells is defined as those cells arising from the mitotic division of a single somatic cell with the same rearrangement of immunoglobulin genes. This gives rise to DNA markers for each individual lymphoid cell and its progenies and enables us to study clonality in different B-cell malignancies using multiplex polymerase chain reaction - PCR. The BIOMED-2 protocol has been implemented for clonality detection in lymphoproliferative diseases and exploits multiplex PCR reaction, subsequently analyzed by heteroduplex analysis (HDA) using polyacrylamide gel electrophoresis (PAGE). With the advent of miniaturization and automation of molecular biology methods, lab-on-chip technologies were developed and replace partially the conventional approaches. We tested device for microfluidic chip, which is used for B-cells clonality analysis, using a PCR reaction for three subregions called frameworks (FR) of the immunoglobulin heavy locus (IGH) gene.

Material and Methods: For the implementation and comparison of the two methods we analyzed three unknown B-cell chronic lymphocytic leukemia (B-CLL) samples. As positive control (PK) we used one formalin-fixed, paraffin-embedded (FFPE) sample from B-CLL lymph node. The DNA was extracted from FFPE sections and multiplex PCR was used to amplify IGH gene segments. After PCR, the HDA was performed, the DNA fragments were evaluated on the PAGE and the microfluidic chip electrophoresis as well, and the results were compared.

Results: Using HDA with subsequent PAGE, we were able to confirm the clonality of the positive control and the tested samples. The same results were obtained by the Bioanalyzer 2100. The microfluidic chip electrophoresis was persuasive in all tested samples.

Conclusion: The implementation of microfluidic chip electrophoresis for detection of B-cell clonality by BIOMED-2 protocol on the device Agilent 2100 Bioanalyzer was successful and yielded the same results as the HDA - PAGE. Moreover, chip electrophoresis system is faster for preparation and less laborious than the conventional HDA - PAGE method.
Analysis of Autonomic Nervous System Functional Age and Heart Rate Variability in Mine Workers
Authors: Vasicko T , Prindesova-Busikova J , Osina O 
Published: June 2016

Abstract

Introduction: Heavy working conditions and many unpropitious factors influencing workers health participate in development of various health disorders, among other autonomic cardiovascular regulation malfunction. The aim of this study is to draw a comparison of autonomic nervous system functional age and heart rate variability changes between workers with and without mining occupational exposure.

Material and methods: Short term HRV was measured by DiANS PF8 device in men with and without occupational mining exposure (exposure for 10 years at least) using standard orthoclinostathic protocol (each phase 300 sec or 300 heartbeats if heart rate under 60 bpm), excluding those with severe cardiovascular, metabolic, or psychiatric diseases, nicotine and other drugs abuse, as well as those, who underwent heavy stress situation during last year.

Results: Evaluating 41 HRV records among miners (n=24, age 47.9 ± 6.1 years, exposure 22.5 ± 5 years) and non-miners (n=17, age 48.5 ± 6.9 years) we found significantly increased difference between functional age of ANS and calendar age in miners group (+7.2 ± 7.3 years) over against the non-miners group (−1.6 ± 6.5 years). No correlation was found between exposure duration and functional age of ANS difference. Analysis of HRV parameters show significant reduction in total spectral power, LF, HF and rMSSD in mine workers above 48 years of age.

Discussion and conclusion: Our results show that influence of occupational work factors from mining exposure can clearly take part in worsening the reactivity of ANS, which can be associated with greater risk of developing mostly cardiovascular diseases. It is important to think of non-occupational factors improving or deteriorating ANS reactivity and of individual sensitivity to other external factors.
Application of a new method to control microbial quality of foods based on the detection of oxygen consumption
Authors: Lehotová Veronika , Petruláková Monika , Valík Ľubomír 
Published: June 2016

Abstract
New analytical techniques, the GreenLight™ system for rapid enumeration of total viable counts (TVC) were used to estimate the numbers of bacteria inoculated in different levels in broth nutrient media. The new detection methodology was compared with agar plating EN ISO 4833:2003 method showing excellent correlation. The following coefficients of determination R2 = 0.985 and 0.999 were calculated for aerobic Pseudomonas aeruginosa and facultative anaerobic E. coli, respectively. After calibration, the system based on the principle of quenching of luminescence intensity and lifetime of an oxygen-sensitive dye by sample O2 consumed during microbial growth enables to determine the number of microorganisms within less than 24 hours. The higher microbial load the shorter time for determination of viable count is needed. In case of simple food matrix for example, the results can be reached even within one shift of production.
Influence of Tempering on Mechanical Properties of Induction Bents below 540°C
Authors: Jankejech Peter , Fabian Peter , Broncek Jozef , Shalapko Yuriy 
Published: June 2016

Abstract
The article describes basic principles of induction bending and the change of mechanical properties from as received (straight) pipe made from HSLA steel to induction bend. The main purpose of this article is to experiment with tempering temperatures below 540°C. After tempering at 540°C which is the lowest recommended temperature for post bend heat treatment (PBHT) according to CSA specifications (Canadian Standards Association) the induction bend area in many cases does not achieve the minimum required mechanical properties and therefore it is not accepted for usage. In this article mechanical properties such as tensile, toughness, hardness are evaluated. Also the article contains microstructural analyses and comparison of bended and heat treated samples.
Transient Vibrations of an Elastic Cylinder Inserted in the Elastic Medium
Authors: Sulym Heorgij , Timar Imre , Turchyn Ihor 
Published: June 2016

Abstract
Using method of Laguerre polynomials we have obtained the solution of the dynamic problem of the theory of elasticity for elastic cylinder inserted into massive body modeled as a space. The source of non-stationary processes in composite is high intensity force load of the inner surface of the cylinder. On the surface separation of materials of space and cylinder the conditions of ideal mechanical contact are satisfied. The solution is obtained as series of Laguerre polynomials, which coefficients are found from recurrent relations. The results of numerical analysis of transient stress-strain state in elastic space with cylindrical insertion might be used for the technological process of hydraulic fracturing during shale gas extraction.
Modelling the Meshing of Cycloidal Gears
Authors: Nachimowicz Jerzy , Rafałowski Stanisław 
Published: June 2016

Abstract
Cycloidal drives belong to the group of planetary gear drives. The article presents the process of modelling a cycloidal gear. The full profile of the planetary gear is determined from the following parameters: ratio of the drive, eccentricity value, the equidistant (ring gear roller radius), epicycloid reduction ratio, roller placement diameter in the ring gear. Joong-Ho Shin’s and Soon-Man Kwon’s article (Shin and Know, 2006) was used to determine the profile outline of the cycloidal planetary gear lobes. The result was a scatter chart with smooth lines and markers, presenting the full outline of the cycloidal gear.
Coupled Static and Dynamic Buckling Modelling of Thin-Walled Structures in Elastic Range Review of Selected Problems
Authors: Kołakowski Zbigniew , Teter Andrzej 
Published: June 2016

Abstract
A review of papers that investigate the static and dynamic coupled buckling and post-buckling behaviour of thin-walled structures is carried out. The problem of static coupled buckling is sufficiently well-recognized. The analysis of dynamic interactive buckling is limited in practice to columns, single plates and shells. The applications of finite element method (FEM) or/and analytical-numerical method (ANM) to solve interaction buckling problems are on-going. In Poland, the team of scientists from the Department of Strength of Materials, Lodz University of Technology and co-workers developed the analytical-numerical method. This method allows to determine static buckling stresses, natural frequencies, coefficients of the equation describing the post-buckling equilibrium path and dynamic response of the plate structure subjected to compression load and/or bending moment. Using the dynamic buckling criteria, it is possible to determine the dynamic critical load. They presented a lot of interesting results for problems of the static and dynamic coupled buckling of thin-walled plate structures with complex shapes of cross-sections, including an interaction of component plates. The most important advantage of presented analytical-numerical method is that it enables to describe all buckling modes and the post-buckling behaviours of thin-walled columns made of different materials. Thin isotropic, orthotropic or laminate structures were considered.
Avian Crop Function – A Review
Authors: Kierończyk Bartosz , Rawski Mateusz , Długosz Jakub , Świątkiewicz Sylwester , Józefiak Damian 
Published: June 2016

Abstract
The aim of this review is to present and discuss the anatomy and physiology of crop in different avian species. The avian crop (ingluvies) present in most omnivorous and herbivorous bird species, plays a major role in feed storage and moistening, as well as functional barrier for pathogens through decreasing pH value by microbial fermentation. Moreover, recent data suggest that this gastrointestinal tract segment may play an important role in the regulation of the innate immune system of birds. In some avian species ingluvies secretes “crop milk” which provides high nutrients and energy content for nestlings growth. The crop has a crucial role in enhancing exogenous enzymes efficiency (for instance phytase and microbial amylase, β-glucanase), as well as the activity of bacteriocins. Thus, ingluvies may have a significant impact on bird performance and health status during all stages of rearing. Efficient use of the crop in case of digesta retention time is essential for birds’ growth performance. Thus, a functionality of the crop is dependent on a number of factors, including age, dietary factors, infections as well as flock management. It is important to expand knowledge about the crop functions to use them effectively in poultry production. Furthermore, more scientific data is needed in the scope of immunological function of the crop as well as its microecosystem for a better understanding of the avian immune system and enhancing the health of the birds.
Sicheres und einfaches Data Sharing mit SowiDataNet: dokumentieren – veröffentlichen – nachnutzen
Authors: Droß Patrick J. , Linne Monika 
Published: June 2016

Zusammenfassung
SowiDataNet ist eine im Aufbau befindliche Forschungsdateninfrastruktur für die Sozial- und Wirtschaftswissenschaften. Zentraler Baustein ist die Entwicklung eines web-basierten Forschungsdatenrepositoriums, welches es Forscherinnen
Aus Gründen der besseren Lesbarkeit wird im Text abwechselnd die weibliche und die männliche Form verwendet. Gemeint sind stets alle Geschlechter.

erlaubt, ihre Daten sicher und dauerhaft zu dokumentieren, zu publizieren und mit anderen Forschern zu teilen. Die Entwicklung dieses neuen Services orientiert sich am konkreten Bedarf der Fachcommunity, was sich u. a. in der Durchführung einer detaillierten Anforderungsanalyse widerspiegelt. Ein spezieller Fokus liegt zudem auf der flexiblen Einbindung des Repositoriums in die praktischen Workflows des institutionellen Forschungsdatenmanagements.
Publikationskompetenz als neues Tätigkeitsfeld von Bibliotheken
Authors: Keller Alice 
Published: June 2016

Zusammenfassung
Der Aufsatz stellt zwei Modelle des wissenschaftlichen Publizierens gegenüber: das traditionelle Dreiecksverhältnis zwischen Wissenschaft, Verlag und Bibliothek und ein neues Modell, das mit verschiedensten Online-Inhaltsanbietern und Publikationsplattformen arbeitet. Das neue Modell des wissenschaftlichen Publizierens verlangt sowohl von den Autoren als auch von den Bibliotheken neue Fähigkeiten, die hier unter dem Begriff Publikationskompetenz zusammengefasst werden. Auf Seite der Autoren bzw. Forscher kann die Publikationskompetenz als (pro-)aktive Form der Informationskompetenz verstanden werden. Bei den Bibliotheken geht es um den Aufbau von publikationsunterstützenden Services. Um diese Angebote professionell betreiben zu können, bedarf es besonderer Fähigkeiten, die sich oft signifikant vom traditionellen bibliothekarischen Aufgabenspektrum unterscheiden. Diese Veränderungen führen zu weitreichenden Konsequenzen für die Bibliotheken, bieten ihnen aber auch neue Chancen, verstärkt mit den Forschenden direkt in Kontakt zu kommen.
Hospitalization of a child in the Neonatal Intensive Care – parents’ experiences
Authors: Kopeć Agnieszka , Aftyka Anna , Humeniuk Ewa , Rybojad Beata , Rozalska-Walaszek Ilona 
Published: June 2016

Abstract
Introduction. Significant progress in the perinatal and intensive care therapy resulted in a meaningful increase of survival of extremely immature, and burdened with severe diseases neonates. Although infants are the patients of the Neonatal Intensive Care Unit, the needs of their parents should also be noticed and realized. The aim of the study was the analysis of the parents’ experiences of children hospitalized in the NICU.
Material. The research material comprises 39 written contributions of parents of children hospitalized in the NICU.
Method. A qualitative analysis of the text was used. Quotes of parents were classified in three categories: emotions, thoughts and support.
Results. Fear, happiness, joy, uncertainty, stress and shock are the most frequently emotions appearing in the parents’ reports. The most frequently mentioned areas of cognitive reactions of parents include: realization of child’s mortality, realizing problems of the premature birth, search for the guilty, and the reformulation of looking at the world. Parents often described support they received, but also pointed to the areas where support lacked.
Conclusion:

As a result of intense emotions, both positive and negative tint that parents experience at birth of a premature or sick child, multi-disciplinary care is necessary in order to reduce the negative effects of experienced emotions.

Support, including information support for parents of critically ill newborns is a key skill in the practice of doctors taking care of children hospitalized in NICU.

Psychological support is an essential element of the holistic care of the neonate’s family.
Adriamycin - efficacy and possible adverse effects
Authors: Pedrycz Agnieszka , Kramkowska Agnieszka 
Published: June 2016

Abstract
Adriamycin (doxorubicin) is a chemical substance in the anthracycline class with a wide range of applications in oncology and hematology. The mechanism of action of Adriamycin is related to formation of irregular bonds between nucleobases of DNA and inhibition of key enzymes of DNA synthesis - topoisomerase I and II as well as to formation of free radicals damaging DNA.
A major limitation in the drug use is associated with its adverse effects such as cardiotoxicity and hepatotoxicity.
The mechanism of myocardial injury by Adriamycin is linked to an increase in oxidative stress associated with impaired mitochondrial function and structure.
Cardiotoxicity of anthracyclines is classified as: acute, chronic or late (delayed).
Hepatotoxicity of Adriamycin as a damage of the liver is associated with a dysfunction of this organ. Adriamycin studies have shown increased level of transaminase present in 40% of patients treated with Adriamycin. The state was transient and asymptomatic, returning to the initial level even when treatment continued.
Knowledge of cancer diseases contributed to a successive creation of two improved forms of Adriamycin (doxorubicin) – nonpegylated and pegylated formulas of the drug.
The mechanism of anticancer effects of liposomal Adriamycin is similar to the mechanism of conventional Adriamycin, but placement of the molecules of active substance in liposomes has significant influence on the distribution of the drug.
In order to increase the distribution of the drug, a special form of liposomal Adriamycin has been created by covering the surface of the liposomes with a hydrophilic polymer - (MPEG). This process, known as pegylation, decreases the interactions between the lipid bilayer membrane and the plasma components. Pegylated form of the drug is associated with a higher incidence of acute complications.
Do Environmental Education School Coordinators Have a Mission?
Authors: Šimonová Petra , Činčera Jan 
Published: June 2016

Abstract
Teachers who are specialized in environmental education (environmental education school coordinators1) can play an important role in empowering students to shape a sustainable future. In this study, the authors examined a group of Czech environmental education school coordinators. The authors aimed to clarify how they interpret their role at their respective schools, how they perceive their self-efficacy, and what they observe as benefits and barriers to their work as a coordinator. They conducted a qualitative study with focus groups and completed individual in-depth interviews with the coordinators. The results suggest that the coordinators view their work as a mission. The ultimate goal of this mission is to change the children’s behavior to make it more pro-environmental, and, at the same time, to establish this effort as a commitment of the whole school. The authors identified different forms of mission, described development in time and connected them with the perceived self-efficacy of the coordinators.
Interethnic variability of pharmacogenetic biomarkers in Mexican healthy volunteers: a report from the RIBEF (Ibero-American Network of Pharmacogenetics and Pharmacogenomics)
Authors: Fricke-Galindo Ingrid , Jung-Cook Helgi , LLerena Adrián , López-López Marisol 
Published: June 2016

Abstract
Mexico presents a complex population diversity integrated by Mexican indigenous (MI) (7% of Mexico’s population) and Mexican mestizos (MMs). This composition highlights the importance of pharmacogenetic studies in Mexican populations. The aims of this study were to analyze the reported frequencies of the most relevant pharmacogenetic biomarkers and metabolic phenotypes in healthy volunteers from Mexican populations and to assess its interethnic variability across MI and MM populations. After a literature search in PubMed, and according to previously defined inclusion criteria, 63 pharmacogenetic studies performed in Mexican healthy volunteers up to date were selected. These reports comprised 56,292 healthy volunteers (71.58% MM). Allele frequencies in 31 pharmacogenetic biomarkers, from 121 searched, are described. Nine of these biomarkers presented variation within MM and MI groups. The frequencies of CYP2D6*3, *4, *5, *10, *17, *35 and *41 alleles in the MM group were different from those reported in the MI group. CYP2C9*2 and *3 alleles were more frequent in MM than in MI populations (χ2 test, p<0.05). CYP2C19*3 allele was not found in the MM or MI populations reported. For UGT1A1*28, only one study was found. HLA-A*31:01 and HLA-B*15:02 were present in some MM and MI populations. Poor metabolizers for CYP2D6 and CYP2C9 were more frequent in MM than in MI groups (χ2 test, p<0.05). Only 26% of the relevant pharmacogenetic biomarkers searched have been studied in Mexican healthy volunteers; therefore, further studies are warranted. The frequency variation of biomarkers in MM and MI populations could be important for the clinical implementation of pharmacogenetics in Mexico.