bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing evidence-based continuous quality improvement strategies in an urban Aboriginal Community Controlled Health Service in South East Queensland: a best practice implementation pilot
Authors: Hogg Sandra , Roe Yvette , Mills Richard 
Published: January 2017

EXECUTIVE SUMMARY

Background:
The Institute for Urban Indigenous Health believes that continuous quality improvement (CQI) contributes to the delivery of high-quality care, thereby improving health outcomes for Aboriginal and Torres Strait Islander people. The opening of a new health service in 2015 provided an opportunity to implement best practice CQI strategies and apply them to a regional influenza vaccination campaign.

Objective:
The aim of this project was to implement an evidence-based CQI process within one Aboriginal Community Controlled Health Service in South East Queensland and use staff engagement as a measure of success.

Method:
A CQI tool was selected from the Joanna Briggs Institute Practical Application of Clinical Evidence System (PACES) to be implemented in the study site. The study site was a newly established Aboriginal and Torres Strait Islander Community Controlled Health Service located in the northern suburbs of Brisbane. This project used the evidence-based information collected in PACES to develop a set of questions related to known variables resulting in proven CQI uptake. A pre implementation clinical audit, education and self-directed learning, using the Plan Do Study Act framework, included a total of seven staff and was conducted in April 2015. A post implementation audit was conducted in July 2015.

Results:
There were a total of 11 pre- and post-survey respondents which included representation from most of the clinical team and medical administration. The results of the pre implementation audit identified a number of possible areas to improve engagement with the CQI process including staff training and support, understanding CQI and its impacts on individual work areas, understanding clinical data extraction, clinical indicator benchmarking, strong internal leadership and having an external data extractor. There were improvements to all audit criteria in the post–survey, for example, knowledge regarding the importance of CQI activity, attendance at education and training sessions on CQI, active involvement with CQI activity and a multidisciplinary team approach to problem solving within the CQI process.

Conclusion:
The study found that the implementation of regular, formally organized CQI strategies does have an immediate impact on clinical practice, in this case, by increasing staff awareness regarding the uptake of influenza vaccination against regional targets. The Plan Do Study Act cycle is an efficient tool to record and monitor the change and to guide discussions. For the CQI process to be effective, continued education and training on data interpretation is pivotal to improve staff confidence to engage in regular data discussions, and this should be incorporated into all future CQI sessions.
Transformation of an Aviation Turboshaft Engine Into a Experimental Jet Engine for Laboratory Testing Unstable Radial Compressor Work
Authors: Hocko Marián , Polansky Jiri 
Published: January 2017

The article deals with the use of a small aviation turboshaft engine for laboratory purposes. This study describes its transformation into an experimental device for research and education. Various constructional, technological and controlling modifications and settings of the gas turbine test stand were carried out and tested on a stationary configuration. The stationary system can be used as a small backup power generator or as a drive unit for a compressor, pump, etc. New control systems, electronic elements and methods of measuring rotations, pressure and temperature are tested for educational and research purposes. The study includes a schematic description of modelling measurements and subsequent numerical evaluation of the thermodynamic characteristics of the cycle in an experimental gas turbine. The laboratory device presented here is, thanks to technological, material and thermodynamic research, suitable for educating and testing the knowledge of future aviation and mechanical engineers.
The content of the article is a description of the use of transformed small turboshaft engine into small jet engine by means of experimental testing of unstable work of the radial compressor under laboratory conditions.
Draft Genome Sequences of 15 Staphylococcus aureus Isolates Recovered from Raw Milk and Associated Milk Filters from Victoria, Australia
Authors: McMillan Kate , Allnutt Theodore R. , Fox Edward M. 
Published: January 2017

ABSTRACT

This study describes draft whole genomes of 15
Staphylococcus aureus
isolates from dairy farms located in Victoria, Australia. Two novel sequence types (ST3183 and ST3184) were identified among these isolates.
Draft Genome Sequence of Pseudomonas aeruginosa Strain Hex1T Isolated from Soils Contaminated with Used Lubricating Oil in Argentina
Authors: Luján Adela M. , Feliziani Sofía , Smania Andrea M. 
Published: January 2017

ABSTRACT

Pseudomonas aeruginosa
Hex1T was isolated from soils contaminated with used lubricating oil from a garage in Córdoba, Argentina. This strain is capable of utilizing this pollutant as the sole carbon and energy source. Here, we present the 6.9-Mb draft genome sequence of Hex1T, which contains many heavy metal-resistance genes.
Direct-to-consumer advertising of success rates for medically assisted reproduction: a review of national clinic websites
Authors: Wilkinson Jack , Vail Andy , Roberts Stephen A 
Published: January 2017

ObjectivesTo establish how medically assisted reproduction (MAR) clinics report success rates on their websites.SettingWebsites of private and NHS clinics offering in vitro fertilisation (IVF) in the UK.ParticipantsWe identified clinics offering IVF using the Choose a Fertility Clinic facility on the website of the Human Fertilisation and Embryology Authority (HFEA). Of 81 clinics identified, a website could not be found for 2, leaving 79 for inclusion in the analysis.Primary and secondary outcome measuresOutcome measures reported by clinic websites. The numerator and denominator included in the outcome measure were of interest.Results53 (67%) websites reported their performance using 51 different outcome measures. It was most common to report pregnancy (83% of these clinics) or live birth rates (51%). 31 different ways of reporting pregnancy and 9 different ways of reporting live birth were identified. 11 (21%) reported multiple birth or pregnancy rates. 1 clinic provided information on adverse events. It was usual for clinics to present results without relevant contextual information such as sample size, reporting period, the characteristics of patients and particular details of treatments.ConclusionsMany combinations of numerator and denominator are available for the purpose of reporting success rates for MAR. The range of reporting options available to clinics is further increased by the possibility of presenting results for subgroups of patients and for different time periods. Given the status of these websites as advertisements to patients, the risk of selective reporting is considerable. Binding guidance is required to ensure consistent, informative reporting.
Efficacy of combined conservative therapies on clinical outcomes in patients with thumb base osteoarthritis: protocol for a randomised, controlled trial (COMBO)
Authors: Deveza Leticia A , Hunter David J , Wajon Anne , Bennell Kim L , Vicenzino Bill , Hodges Paul , Eyles Jillian P , Jongs Ray , Riordan Edward A , Duong Vicky , Min Oo Win , O'Connell Rachel , Meneses Sarah R F 
Published: January 2017

IntroductionManagement of thumb base osteoarthritis (OA) using a combination of therapies is common in clinical practice; however, evidence for the efficacy of this approach is lacking. The aim of this study is to determine the effect of a combination of conservative therapies for the treatment of thumb base OA compared with an education control group.Methods and analysisThis is a randomised, controlled, single-centre, two-arm superiority trial with 1:1 allocation ratio; with assessor and statistician blinded. Participants are blinded to the trial's hypothesis and to the interventions received by the opposite group. A total of 204 participants will be recruited from the community and randomised using a computer-generated schedule. The intervention group will receive education for joint protection and OA, a splint for the base of the thumb, hand exercises and topical diclofenac sodium 1% gel over 6 weeks. The control group will receive education for joint protection and OA alone. Main inclusion criteria are pain ≥40 mm (Visual Analogue Scale, 0–100) at the base of the thumb, impairment in hand function ≥6 (Functional Index for Hand Osteoarthritis, 0–30) and radiographic thumb base OA (Kellgren Lawrence grade ≥2). Participants currently receiving any of the intervention components will be excluded. Outcomes will be measured at 2, 6 and 12 weeks. The primary outcome is change in pain and hand function from baseline to 6 weeks. Other outcomes include changes in grip and pinch strength, quality of life, presence of joint swelling and tenderness, duration of joint stiffness, patient's global assessment and use of rescue medication. Analysis will be performed according to the intention-to-treat principle. Adverse events will be monitored throughout the study.Ethics and disseminationThis protocol is approved by the local ethics committee (HREC/15/HAWKE/479). Dissemination will occur through presentations at international conferences and publication in peer-reviewed journals.Trial registration numberACTRN12616000353493; Pre-results.
Improvement of microwave magnetic properties by inserting nonmagnetic layer
Authors: Li Xiaoting , An Chao , Wang Zhen , Xu Chunlong , Shi Gang , Wang Jinguo , Hou Zhaoyang , Xi Li 
Published: January 2017

Co/NM (nonmagnetic Ag and SiO2)/Co sandwich structure films with different thicknesses of NM were fabricated on Si(111) substrate via oblique radio frequency sputtering. With increasing thickness of nonmagnetic Ag [Formula: see text], in-plane magnetic anisotropy field [Formula: see text] initially increased from 100 Oe of [Formula: see text] nm to 220 Oe of [Formula: see text] nm, and then decreased when [Formula: see text] nm. Resonance frequency showed the same tendency with maximum 5.2 GHz when [Formula: see text] nm. Damp factor increased from 0.02 for [Formula: see text] for [Formula: see text] nm. The same result was observed in inserting oxide nonmagnetic SiO2 layer. This can be attributed to the competition between interface energy and exchange coupling energy.
Kinetics of circulating progenitor cell mobilization during submaximal exercise
Authors: Niemiro Grace M. , Parel Justin , Beals Joseph , van Vliet Stephan , Paluska Scott A. , Moore Daniel R. , Burd Nicholas A. , De Lisio Michael 
Published: January 2017

Circulating progenitor cells (CPCs) are a heterogeneous population of stem/progenitor cells in peripheral blood that includes hematopoietic stem and progenitor cells (HSPCs and HSCs), endothelial progenitor cells (EPCs), and mesenchymal stem cells (MSCs) that are involved in tissue repair and adaptation. CPC mobilization during exercise remains uncharacterized in young adults. The purpose of this study was to investigate the kinetics of CPC mobilization during and after submaximal treadmill running and their relationship to mobilization factors. Seven men [age = 25.3 ± 2.4 yr, body mass index = 23.5 ± 1.0 kg/m2, peak O2uptake (V̇o2peak) = 60.9 ± 2.74 ml·kg−1·min−1] ran on a treadmill for 60 min at 70% V̇o2peak. Blood sampling occurred before (Pre), during [20 min (20e), 40 min (40e), 60 min (60e)], and after exercise [15 min (15p), 60 min (60p), 120 min (120p)] for quantification of CPCs (CD34+), HSPCs (CD34+/CD45low), HSCs (CD34+/CD45low/CD38−), CD34+MSCs (CD45−/CD34+/CD31−/CD105+), CD34−MSCs (CD45−/CD34−/CD31−/CD105+), and EPCs (CD45−/CD34+/CD31+) via flow cytometry. CPC concentration increased compared with Pre at 20e and 40e (2.7- and 2.4-fold, respectively, P < 0.05). HSPCs and HSCs increased at 20e compared with 60p (2.7- and 2.8-fold, respectively, P < 0.05), whereas EPCs and both MSC populations did not change. CXC chemokine ligand (CXCL) 12 (1.5-fold; P < 0.05) and stem cell factor (1.3-fold; P < 0.05) were increased at 40e and remained elevated postexercise. The peak increase in CPCs was positively correlated to concentration of endothelial cells during exercise with no relationship to CXCL12 and SCF. Our data show the kinetics of progenitor cell mobilization during exercise that could provide insight into cellular mediators of exercise-induced adaptations, and have implication for the use of exercise as an adjuvant therapy for CPC collection in hematopoietic stem cell transplant.NEW & NOTEWORTHY Using a comprehensive evaluation of circulating progenitor cells (CPCs), we show that CPC mobilization during exercise is related to tissue damage, and not plasma concentrations of CXC chemokine ligand 12 and stem cell factor. These data have implications for the use of exercise interventions as adjuvant therapy for CPC mobilization in the context of hematopoietic stem cell transplant and also support the role of mobilized progenitor cells as cellular mediators of systemic adaptations to exercise.
Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve–Dependent Regulation of NKG2D and CCR5
Authors: Song Yanfang , Gan Yu , Wang Qing , Meng Zihong , Li Guohua , Shen Yuling , Wu Yufeng , Li Peiying , Yao Ming , Gu Jianren , Tu Hong 
Published: January 2017

Abstract
Mice housed in an enriched environment display a tumor-resistant phenotype due to eustress stimulation. However, the mechanisms underlying enriched environment–induced protection against cancers remain largely unexplained. In this study, we observed a significant antitumor effect induced by enriched environment in murine pancreatic cancer and lung cancer models. This effect remained intact in T/B lymphocyte-deficient Rag1−/− mice, but was nearly eliminated in natural killer (NK) cell–deficient Beige mice or in antibody-mediated NK-cell–depleted mice, suggesting a predominant role of NK cells in enriched environment–induced tumor inhibition. Exposure to enriched environment enhanced NK-cell activity against tumors and promoted tumoral infiltration of NK cells. Enriched environment increased the expression levels of CCR5 and NKG2D (KLRK1) in NK cells; blocking their function effectively blunted the enriched environment–induced enhancement of tumoral infiltration and cytotoxic activity of NK cells. Moreover, blockade of β-adrenergic signaling or chemical sympathectomy abolished the effects of enriched environment on NK cells and attenuated the antitumor effect of enriched environment. Taken together, our results provide new insight into the mechanism by which eustress exerts a beneficial effect against cancer. Cancer Res; 77(7); 1611–22. ©2017 AACR.
High-Intensity Interval Training in Patients With Heart Failure With Reduced Ejection Fraction
Authors: Ellingsen Øyvind , Halle Martin , Conraads Viviane , Støylen Asbjørn , Dalen Håvard , Delagardelle Charles , Larsen Alf-Inge , Hole Torstein , Mezzani Alessandro , Van Craenenbroeck Emeline M. , Videm Vibeke , Beckers Paul , Christle Jeffrey W. , Winzer Ephraim , Mangner Norman , Woitek Felix , Höllriegel Robert , Pressler Axel , Monk-Hansen Tea , Snoer Martin , Feiereisen Patrick , Valborgland Torstein , Kjekshus John , Hambrecht Rainer , Gielen Stephan , Karlsen Trine , Prescott Eva , Linke Axel 
Published: January 2017

Background:
Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart failure with reduced ejection fraction. The present multicenter trial compared 12 weeks of supervised interventions of HIIT, MCT, or a recommendation of regular exercise (RRE).

Methods:
Two hundred sixty-one patients with left ventricular ejection fraction ≤35% and New York Heart Association class II to III were randomly assigned to HIIT at 90% to 95% of maximal heart rate, MCT at 60% to 70% of maximal heart rate, or RRE. Thereafter, patients were encouraged to continue exercising on their own. Clinical assessments were performed at baseline, after the intervention, and at follow-up after 52 weeks. Primary end point was a between-group comparison of change in left ventricular end-diastolic diameter from baseline to 12 weeks.

Results:

Groups did not differ in age (median, 60 years), sex (19% women), ischemic pathogenesis (59%), or medication. Change in left ventricular end-diastolic diameter from baseline to 12 weeks was not different between HIIT and MCT (
P
=0.45); left ventricular end-diastolic diameter changes compared with RRE were −2.8 mm (−5.2 to −0.4 mm;
P
=0.02) in HIIT and −1.2 mm (−3.6 to 1.2 mm;
P
=0.34) in MCT. There was also no difference between HIIT and MCT in peak oxygen uptake (
P
=0.70), but both were superior to RRE. However, none of these changes was maintained at follow-up after 52 weeks. Serious adverse events were not statistically different during supervised intervention or at follow-up at 52 weeks (HIIT, 39%; MCT, 25%; RRE, 34%;
P
=0.16). Training records showed that 51% of patients exercised below prescribed target during supervised HIIT and 80% above target in MCT.

Conclusions:
HIIT was not superior to MCT in changing left ventricular remodeling or aerobic capacity, and its feasibility remains unresolved in patients with heart failure.

Clinical Trial Registration:

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT00917046.
Telemedicine Can Replace the Neurologist on a Mobile Stroke Unit
Authors: Wu Tzu-Ching , Parker Stephanie A. , Jagolino Amanda , Yamal Jose-Miguel , Bowry Ritvij , Thomas Abraham , Yu Amy , Grotta James C. 
Published: January 2017

Background and Purpose—
The BEST-MSU study (Benefits of Stroke Treatment Delivered Using a Mobile Stroke Unit) is a comparative effectiveness trial in patients randomized to mobile stroke unit or standard management. A substudy tested interrater agreement for tissue-type plasminogen activator eligibility between a telemedicine vascular neurologist and onboard vascular neurologist.

Methods—
On scene, both the telemedicine vascular neurologist and onboard vascular neurologist independently evaluated the patient, documenting their tissue-type plasminogen activator treatment decision, National Institutes of Health Stroke Scale score, and computed tomographic interpretation. Agreement was determined using Cohen κ statistic. Telemedicine-related technical failures that impeded remote assessment were recorded.

Results—
Simultaneous and independent telemedicine vascular neurologist and onboard vascular neurologist assessment was attempted in 174 patients. In 4 patients (2%), the telemedicine vascular neurologist could not make a decision because of technical problems. The telemedicine vascular neurologist agreed with the onboard vascular neurologist on 88% of evaluations (κ=0.73).

Conclusions—
Remote telemedicine vascular neurologist assessment is reliable and accurate, supporting either telemedicine vascular neurologist or onboard vascular neurologist assessment on our mobile stroke unit.

Clinical Trial Registration—

URL:
http://www.clinicaltrials.gov
. Unique identifier: NCT02190500.
Problem un ou deux phonèmes? w języku polskim
Authors: Wągiel Marcin 
Published: January 2017

The un ou deux phonèmes? problem in PolishThe paper deals with the so-called un ou deux phonèmes? problem in Modern Polish. The framework adopted by the author is the theory and methodology of Axiomatic Functionalism, i.e., a functional semiotic approach developed by Jan W. F. Mulder in association with Sándor G. J. Hervey which is mainly based on linguistic ideas of André Martinet. The analysis focuses on the phonological interpretation of sequences of palatalized labials and [j], nasal diphthongs, and affricates in Polish. The author argues that nasal diphthongs and palatal and retroflex affricates should be interpreted monophonematically, whereas it is both adequate and economical to interpret sequences of palatalized labials and [j] and alveolar affricates as realizations of sequences of two separate phonemes. Problem un ou deux phonèmes? w języku polskimNiniejszy artykuł poświęcony jest tzw. problemowi un ou deux phonèmes? we współczesnej polszczyźnie. Aparatem pojęciowym wykorzystanym przez autora jest teoria i metodologia funkcjonalizmu aksjomatycznego, tj. funkcjonalnego opisu semiotycznego opracowanego przez Jana W. F. Muldera we współpracy z Sándorem G. J. Herveyem, który bazuje na koncepcjach lingwistycznych André Martineta. Analiza skupia się na interpretacji fonologicznej sekwencji spalatalizowanych spółgłosek labialnych oraz [j], dyftongów nazalnych, a także afrykat w języku polskim. Autor argumentuje, że dyftongi nazalne oraz afrykaty palatalne i retrofleksyjne powinny być interpretowane monofonemicznie, natomiast interpretacja sekwencji spalatalizowanych spółgłosek labialnych i [j] oraz afrykat alweolarnych jako realizacji sekwencji dwóch niezależnych fonemów jest zarówno adekwatna, jak i ekonomiczna.
Międzynarodowa konferencja naukowa "Nowoczesne systemy slawistycznej informacji bibliograficznej – dziś i jutro" (Warszawa, 8–9 października 2015)
Authors: Rudnik-Karwatowa Zofia 
Published: January 2017

International scientific conference Nowoczesne systemy slawistycznej informacji bibliograficznej – dziś i jutro (Warsaw, 8–9 October 2015)The article is a report from a conference organised in Warsaw on 8–9 October 2015 by the Slavic Academic Information Centre (Institute of Slavic Studies, Polish Academy of Sciences), the Slavic Foundation and the Linguistic Bibliography Committee of the International Committee of Slavists. It was the second conference over the span of the last three years devoted to the newest trends in and future development of Slavic studies information systems. Międzynarodowa konferencja naukowa Nowoczesne systemy slawistycznej informacji bibliograficznej – dziś i jutro (Warszawa, 8–9 października 2015)Artykuł stanowi sprawozdanie z międzynarodowej konferencji zorganizowanej w Warszawie 8–9 października 2015 roku przez Centrum Slawistycznej Informacji Naukowej Instytutu Slawistyki Polskiej Akademii Nauk, Fundację Slawistyczną i Komisję Bibliografii Lingwistycznej przy Międzynarodowym Komitecie Slawistów. Była to druga na przestrzeni ostatnich trzech lat konferencja poświęcona najnowszym trendom w systemach slawistycznej bibliograficznej oraz ich rozwojowi w przyszłości.
Precipitation Drivers of Cropping Frequency in the Brazilian Cerrado: Evidence and Implications for Decision-Making
Authors: Spangler Keith R. , Lynch Amanda H. , Spera Stephanie A. 
Published: January 2017

Abstract
The Amazon basin has been subjected to unprecedented rates of land-use change over the past several decades, primarily as a result of the expansion of agriculture. Enhanced rain forest conservation efforts toward the end of the twentieth century slowed deforestation of the Amazon but, in turn, increased demand for land repurposing in the adjacent Cerrado (savanna) region, where conservation regulations are less strict. To maintain or increase yields while minimizing the need for additional land, agricultural producers adopted a form of intensification in which two rain-fed crops are planted within a single growing season (double cropping). Using 10 years (August 2002 to July 2012) of MODIS and TRMM data, it is demonstrated that there exists a threshold growing season rainfall amount (1759 mm) for double cropping. But more nuanced is the relationship between observable precipitation information available to farmers at the time of planting decision and the choice to “double crop” in a given year. An evaluation of decision-available precipitation characteristics provides strong evidence for the importance of high rainfall frequency during a critical period prior to, and including, the rainy season onset.