bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal trends in concordance between ICD-coded and cardiac biomarker-classified hospitalisation rates for acute coronary syndromes: a linked hospital and biomarker data study
Authors: Zemedikun Dawit , Hung Joseph , Lopez Derrick , Knuiman Matthew , Youens David , Briffa Tom G , Sanfilippo Frank , Nedkoff Lee 
Published: October 2024

BackgroundSince 2000, the definition of myocardial infarction (MI) has evolved with reliance on cardiac troponin (cTn) tests. The implications of this change on trends of acute coronary syndrome (ACS) subtypes obtained from routinely collected hospital morbidity data are unclear. Using person-linked hospitalisation data, we compared International Classification of Diseases (ICD)-coded data with biomarker-classified admission rates for ST-segment elevation MI (STEMI), non-STEMI (NSTEMI) and unstable angina (UA) in Western Australia (WA).MethodsWe used linked hospitalisation data from all WA tertiary hospitals to identify patients with a principal diagnosis of STEMI, NSTEMI or UA between 2002 and 2016. Linked biomarker results were classified as ‘diagnostic’ for MI according to established criteria. We calculated age-standardised and sex-standardised rates (ASSRs) for ICD-coded versus biomarker-classified admissions by ACS subtypes and estimated annual change in admissions using Poisson regression adjusting for age and sex.ResultsThere were 37 272 ACS admissions in 30 683 patients (64.2% male), and 96% of cases had linked biomarker data, predominantly conventional cTn at the start and high-sensitive cTn from late 2013. Despite lower ASSRs, trends in MI classified with a diagnostic biomarker were concordant with ICD-coded admissions rates for both STEMI and NSTEMI. Between 2002 and 2010, STEMI rates declined by 4.1% (95% CI 5.0%, 3.1%) and 3.4% (95% CI 4.6%, 2.3%) in ICD-coded and biomarker-classified admissions, respectively, and both plateaued thereafter. For NSTEMI between 2002 and 2010, the ICD-coded and biomarker-classified rates increased 8.0% per year (95% CI 7.2%, 8.9%) and 8.0% (95% CI 7.0%, 9.0%), respectively, and both subsequently declined. For UA, both ICD-coded and biomarker-classified UA admission rates declined in a steady and concordant manner between 2002 and 2016.ConclusionsThe present study supports the validity of using administrative data to monitor population trends in ACS subtypes as they appear to generally reflect the redefinition of MI in the troponin era.
The mSQUASH is a feasible and valid measurement tool to uniformly assess daily physical activity in patients with rheumatic diseases
Authors: van der Kraan Yvonne M , Gensler Lianne , Paap Davy , Thovmasyan Ellen , Ausma Noa , Kokol Helene , Carbo Marlies , Kieskamp Stan C , de Leeuw Karina , van der Geest Kornelis S M , Bootsma Hendrika , Spoorenberg Anneke , Arends Suzanne 
Published: October 2024

BackgroundThe modified Short QUestionnaire to ASsess Health-enhancing physical activity (mSQUASH) was originally developed and validated in Dutch patients with axial spondyloarthritis (axSpA). To support world-wide distribution, applicability and comparability of measuring physical activity, our aim was to perform translation and cross-cultural adaptation of the mSQUASH into English, field testing in other rheumatic diseases and clinical validation in patients with axSpA.MethodsThe Dutch mSQUASH was translated into English according to forward–backward Beaton protocol. Semistructured interviews were conducted in representative samples of patients with axSpA (n=13), Sjögren’s disease (n=10), systemic lupus erythematosus (n=10) and giant cell arteritis/polymyalgia rheumatica (n=10) to verify relevance, comprehensiveness and comprehensibility. For construct validity (n=95), Spearman correlations were used with clinical outcome assessments. For test–retest reliability (n=82), intraclass correlation coefficients (ICC) were calculated. For responsiveness (n=80), standardised response means (SRM) were calculated stratified by Anchor method.ResultsTranslation and cross-cultural adaptation of the mSQUASH into English were successfully carried out, which can serve as basis for other translations. Only minor adaptations and clarifications were implemented. Fair correlations were found between mSQUASH and Axial Spondyloarthritis Disease Activity Score (ρ=−0.31), Bath Ankylosing Spondylitis Functional Index (ρ=−0.37) and Assessment of SpondyloArthritis International Society-Health Index (ρ=−0.30). Test–retest reliability was very good (ICC: 0.87). Responsiveness corresponded to the direction of self-reported changes in physical activity (SRM: 0.72 for improved, 0.06 for stable and −0.74 for worsened).ConclusionThe mSQUASH showed good linguistic and face validity according to field testing in different rheumatic diseases. Clinical validation confirmed good construct validity, test–retest reliability and responsiveness in patients with axSpA, which supports the use of the mSQUASH in clinical practice and research.
Depression, anxiety and cognitive function in persons with inflammatory rheumatic diseases: cross-sectional results from the German National Cohort (NAKO)
Authors: Callhoff Johanna , Berger Klaus , Albrecht Katinka , Strangfeld Anja 
Published: October 2024

ObjectiveTo assess the presence of mental health disorders in persons with rheumatoid arthritis (RA), ankylosing spondylitis (AS), psoriatic arthritis (PsA), systemic lupus erythematosus (SLE) and Sjögren’s disease (SjD) (all: inflammatory rheumatic disease, iRMD) in a population-based cohort.MethodsBaseline data from 101 601 participants of the German National Cohort (NAKO) were analysed. Self-reported physician’s diagnoses of depression and anxiety, the depression scale of the Patient Health Questionnaire (PHQ-9), the Generalised Anxiety Disorder Symptoms Scale (GAD-7), the depression section of the Mini-International Neuropsychiatric Interview (MINI) and cognitive tests on memory and executive functions were analysed. Results of participants with iRMD were compared with participants with osteoarthritis (OA), stratified by age and sex. Cognitive function was described for iRMD and OA using a linear regression model, adjusted for sex and education.Resultsn=3257 participants (3.2%) had an iRMD (2.3% RA, 0.6% AS, 0.5% PsA, 0.2% SLE, 0.1% SjD) and n=24 030 (24%) had OA. Physicians’ diagnoses of depression (26% vs 21%), anxiety (15% vs 11%), current depressive (PHQ-9 ≥10: 13% vs 9.0%) and anxiety symptoms (GAD-7 ≥10: 8.6% vs 5.8%) were more frequent in iRMDs compared with OA. In all age groups, women were more often affected than men. Linear regression models showed no differences in neuropsychological test results between iRMD and OA.ConclusionIndividuals with iRMD frequently experience mental disorders. The study provides an assessment of both self-report and test-based occurrences in this group. Depression and anxiety are more frequent in iRMD compared with OA, whereas levels of cognitive dysfunction were comparable.
Toxicity of crude oil: a systematic review of the acute impacts on Cnidaria
Authors: Vasconcelos Bruna Cristina Ferreira , Cordeiro Ralf Tarciso Silva , Gomes Paula Braga 
Published: October 2024

Cnidarians are ecosystem engineers that play a fundamental role in food webs. However, they are increasingly threatened by anthropogenic activities, such as oil spills, which can cause acute sublethal effects and in some cases, mortality. The literature on this theme is limited and fragmented, with diverse objectives and methodologies, making it challenging to identify consistent patterns and knowledge gaps. This article aims to provide a systematic review of the acute impacts of crude oil and petroleum hydrocarbons on members of the Phylum Cnidaria, to synthesize and integrate the available data. The research followed the PRISMA 2020 guidelines, and employed the search terms: “ crude oil” AND “acute” AND (Cnidaria OR coral), along with the names of each Cnidarian class. The search was restricted to articles published in English from 2013 to 2023, excluding studies that did not directly address the core topic. The number of records collected was relatively low, with only 30 articles identified from 20 studies. The highest number of publications occurred in 2022, and the USA was the most represented country. The Class Anthozoa, particularly corals (order Scleractinia), was the most studied. Research focused on the effects of crude oil on gametes, embryos, larvae, and adults, with most studies examining adult organisms. The majority (56.6%) utilized mixtures of crude oil hydrocarbons, while a smaller proportion (36.6%) focused on pure aromatic hydrocarbons. Most experiments employed water accommodated fractions (36.6%) and continuous flow system (20%). The most common exposure durations (30%) were 96 and 48 h, with exposure times ranging from 18 h to several days. There was significant variation in methodological approaches, underscoring the need for standardized protocols. Research on adult cnidarians primarily assessed health and morphology, lethality, genetic alterations, and symbiont efficiency. In contrast, studies on early life stages focused on lethality, larval metamorphosis, and settlement. Overall, the results indicate that responses vary considerably, particularly concerning exposure time and oil concentration, with sublethal effects at different levels. Further studies incorporating a broader range of species, novel approaches, and the combined effects of elevated temperature and UV radiation are crucial to advancing our understanding of oil impacts on cnidarians.
Atypical Presentation of Tertiary Syphilis
Authors: Cholley Paul , Stievenart Julien , Fayard Damien , Cassagnes Lucie 
Published: October 2024

Syphilis is a sexually transmitted infection characterized by multiple stages. Cardiovascular involvement is a manifestation of tertiary syphilis, occurring between 10 and 40 years after the primary infection. The authors present a case of atypical presentation of tertiary syphilis in a 49-year-old male patient who was admitted to the hospital with bilateral transient loss of vision. Contrast-enhanced CT imaging revealed thoracic aortitis with carotid occlusion, coronary artery stenosis, ischemic stroke, myocardial infarction, and multiple intracardiac thrombi. A postmortem autopsy revealed positive laboratory results for syphilis, which was corroborated by medical autopsy findings of syphilitic aortitis. Keywords: CT-Angiography, Aorta, Cardiac, Vascular, Tertiary Syphilis © RSNA, 2024
Screening of Diabetes‐Associated Autoantigens and Serum Antibody Profiles Using a Phage Display System
Authors: Lin Jun , Wang Zhenyu , Wang Hongtao , Li Yuping , Liu Yao , He Yige , Liu Qian , Chen Zichuan , Ji Yuan 
Published: October 2024

Aims/Introduction: Phage display method is a crucial tool to find novel clinically valuable diabetes‐associated autoantigens and identify known autoantigen epitopes that are associated with diabetes and could provide scientific support and guidance for the artificial construction and synthesis of Type I diabetes mellitus (T1DM) novel biomarkers.Materials and Methods: The phage display system was used for the “biopanning” of T1DM serum. Following the sequencing of the phage DNAs, the homologous sequences of the above fusion heptapeptide were further investigated by BLAST to track the origin of the polypeptide sequences. The antibody spectrum revealed new T1DM‐associated epitopes and antibodies.Results: A total of 1200 phage DNA were sequenced and 9 conserved polypeptide sequences were collected. It was confirmed that the zinc transporter and islet amyloid protease were among them. The conserved polypeptide sequence 8 and another three distinctive polypeptide sequences derived from Proteus were discovered. Furthermore, we expressed recombinant proteins with homologous polypeptide sequences for the human islet amyloid polypeptide (IAPP) and polypeptide precursor human zinc transporter 8 (ZNT8). Through clinical sample detection for the serum from T1DM (n = 100) and T2DM (n = 200) patients, results demonstrate the importance and relevance of these polypeptides in the recognition and classification of various forms of diabetes.Conclusion: Human pancreatic and concurrent bacterial‐derived protein antigens and their epitopes were identified in this research by the phage display system, which is crucial for distinguishing different types of diabetes.
Comparison of Histological, Clinical, and Radiographic Outcomes of Postextraction Ridge Preservation by Allogenic Bone Grafting With and Without Injectable Platelet‐Rich Fibrin: A Double‐Blinded Randomized Controlled Clinical Trial
Authors: Talebi Ardakani Mohammad Reza , Rezaei Esfahrood Zeinab , Mashhadiabbas Fatemeh , Hatami Masoud 
Published: October 2024

Objectives: This randomized controlled clinical trial compared the histological, clinical, and radiographic outcomes of postextraction ridge preservation by allogenic bone grafting with and without injectable platelet‐rich fibrin (I‐PRF).Materials and Methods: Twenty single‐rooted maxillary and mandibular teeth to be extracted and replaced by dental implants were randomly divided into two groups (n = 10). Cone‐beam computed tomography (CBCT) scans were obtained preoperatively to assess bone dimensions and ridge width. The teeth were then extracted, and tooth socket preservation was performed with allograft and collagen type 1 in the control group and allograft, collagen type 1, and I‐PRF in the intervention group. CBCT scans were obtained again 3 months after the first stage of surgery, and the second stage of surgery was performed for implant placement, ridge width measurement, and obtaining a biopsy sample. Radiographic bone width, clinical bone width, and radiographic bone height were measured. A histomorphometric method was applied to quantify residual graft material, new bone formation, and nonmineralized tissues. The data were analyzed with Student’s t‐test and Mann–Whitney U test (α = 0.05).Results: The intervention group showed a significantly smaller reduction in radiographic bone width (P = 0.038) and clinical bone width (P = 0.033), reduction in radiographic bone height (P = 0.213) was not significant. A significantly lower percentage of residual graft particles (P = 0.021) and a significantly higher mean percentage of newly formed bone (P = 0.038) than the control group. However, the difference in the percentage of nonmineralized tissue (P = 0.208) was not significant.Conclusion: Despite the optimal outcome of ridge preservation in both groups, the application of allograft plus I‐PRF yielded superior histological, clinical, and radiographic results compared with allograft alone, and this difference was significant in most variables.
Clinical Outcomes of Double-Kissing Crush or Double-Kissing Culotte in Nonleft Main Bifurcation Lesions: The ROUTE Trial
Authors: Kahraman Serkan , Cizgici Ahmet Y. , Guner Ahmet , Tasbulak Omer , Panc Cafer , Dogan Arda C. , Ulutas Ahmet E. , Gurbak Ismail , Bulut Umit , Avci Yalcin , Demir Ali R. , Yalcin Ahmet A. , Kalkan Ali K. , Erturk Mehmet 
Published: October 2024

BACKGROUND:
Double-kissing (DK) crush and DK culotte are the recommended 2-stent strategies in true coronary bifurcation lesions. However, it is a matter of curiosity about which of the DK crush and DK culotte stenting techniques will have superior results. We aimed to compare the clinical outcomes of DK crush and DK culotte stenting in nonleft main coronary artery bifurcation.

METHODS:
Consecutive patients who received DK crush or DK culotte technique for de novo true nonleft main coronary artery bifurcation lesion were categorized according to which treatment they received. The primary end point of the study was target lesion failure as a composite end point of target lesion revascularization, target vessel myocardial infarction, and cardiac death. Secondary end points were all-cause death and definite stent thrombosis.

RESULTS:

A total of 202 patients were categorized as DK crush (101 patients) or DK culotte (101 patients) techniques. The target lesion failure had occurred frequently in the DK crush (10.9%) compared with the DK culotte (3.0%;
P
=0.028) that was mainly driven by increased target lesion revascularization (9.9% in the DK crush versus 3.0% in the DK culotte;
P
=0.045). The number of patients with target vessel myocardial infarction (3.0% in the DK crush versus 2.0% in the DK culotte;
P
=0.651) and cardiac death (1.0% in the DK crush versus 0.0% in the DK culotte;
P
=0.315) was higher in the DK crush. There were no differences in terms of definite stent thrombosis and all-cause death between groups.

CONCLUSIONS:
In the present analysis, DK culotte was associated with lower 1-year target lesion failure rates compared with DK crush in true nonleft main coronary artery bifurcations.

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT04789161.
The “Wisdom Poem” in Job 28 and its Role in Job’s Final Discourse (Job 27–31)
Authors: Frish Rachel 
Published: October 2024

Abstract
This article offers a fresh interpretation of Job 28 suggesting that it reflects the devout manifestation of the conventional concept of wisdom endorsed by Job’s friends. Articulated by Job, this serves as a rhetorical device in his counterargument to traditional wisdom and his challenge of God himself. The article further demonstrates that the “wisdom poem” is not an independent text but rather serves a distinct function in the rhetorical strategy of Job 27–31, which comprises Job’s final, emphatic rebuttal of his friends’ charges, framed as an oath of innocence.
Comparative analysis of intestinal flora community composition and diversity of Anas platyrhynchos and Anser fabalis in the Yellow River Delta
Authors: Liu Junpeng , Li Linqi , Shao Yan , Li Wenjuan , Li Yanzhao , Wang Hongguo , Wang Yanmei , Zhou Zhihao , Wang Jun , Shang Shuai 
Published: October 2024

Abstract
The Yellow River Delta wetland is a habitat for wintering waterfowl, where mallard (Anas platyrhynchos) and tundra bean goose (Anser fabalis) are commonly observed. Although the intestinal flora plays a pivotal role in maintaining host health and promoting nutrient absorption, it remains unclear whether the same overwintering habitat and challenging feeding conditions specifically affect the composition and diversity of intestinal flora in both species. Here, high-throughput sequencing was used to compare the intestinal bacterial communities of mallard and tundra bean goose from the same region. There was no significant difference in alpha diversity and beta diversity between the two species. Firmicutes and Proteobacteria were the two predominant phyla, accounting for more than 50.00% of the total. They enhanced the nutrient absorption and metabolic efficiency during overwintering. Catellicoccus was the most dominant genus in the intestinal flora of tundra bean goose, accounting for 33.91%, whereas Clostridium sensu stricto 1 was the most dominant genus in mallard, accounting for 7.34%. This difference is considered to be related to the feeding habits of these two species. No significant differences in the structure and diversity of intestinal bacterial communities were observed between mallard and tundra bean goose, and the similarity of intestinal flora between them was high. This study deepens our understanding of the intestinal flora of two coexisting species with different dietary preferences in the Yellow River Delta. It also lays the foundation for waterfowl disease prevention in this area, carrying significant scientific and practical implications for biodiversity and ecosystem conservation.
Manuscripts with the Seal of the Safavid Shrine in Ardabil at the Hekimoğlu Ali Paşa Library in Istanbul
Authors: Tanındı Zeren 
Published: October 2024

Abstract
Shaykh Safi al-Din Ishaq (d. 1334), who founded the Safavid (Safaviyya) Sufi order and gave his name to the Safavid dynasty, lived in Ardabil in northwestern Iran. Shah Ismaʿil (d. 1524), founder of the Safavid state, was buried in a tomb adjoining that of Shaykh Safi. Over time, a complex of buildings grew up around these two tombs and diverse objects were endowed to what became the Shakh Safi al-Din Shrine. Today, the holdings of some libraries and museums in Istanbul include manuscripts containing endowment annotations and the endowment seal of the shrine, most of which also contain the endowment seal of Hekimoğlu Ali Paşa (d. 1758), an Ottoman statesman, as well as a calligrapher, man of letters, and patron of poets. Ali Paşa served for five years in Tabriz, where he established a waqf, as well as in Ardabil and the surrounding region, before being appointed grand vizier (g.v. 1732–35, 1742–43). Shortly after he returned to the capital, he founded a complex there with a library on the grounds, to which he endowed his books, including a large number of works by poets who wrote in Persian. I argue that it must have been Ali Paşa who brought to Istanbul the manuscripts containing the endowment seal and endowment annotations of the Shaykh Safi al-Din Shrine in Ardabil.
The Mevlevīḫāne of Salonica
Authors: Tanman M. Baha 
Published: October 2024

Abstract
Although there is quite a rich bibliography on the history of the Mevlevīḫāne of Salonica, which holds a prominent place among the Mevlevi lodges in Ottoman Europe, the visual sources that could illuminate its architectural features were limited until today to some exterior photographs from the early twentieth century. The building itself no longer exists, save for a few scant traces. I decided to write this article when, at an auction in 2019, I came across some personal items and official documents belonging to Salahaddin Efendi, the last postnişīn (sheikh of a dervish lodge) of this mevlevihane, as well as photographs of its courtyard, kitchen, türbe (mausoleum) and cemetery, and, most importantly, the plan of the main building, which houses the semāʿḫāne (hall in which the semāʿ [the Mevlevi ceremony of prayer, song, and dance] is performed) and the türbe. I hope this essay will be of interest to those who work on Ottoman Sufi architecture and the history of the Mevlevi order in Rumelia.
Mavīzāb and Fuqqāʿ: An Ilkhanid-Period Dispute as Evidence in the Sphero-Conical Vessels Debate
Authors: Rugiadi Martina , Ghouchani † Abdullah , Keyghobadi Roshanak , Allegranzi Viola 
Published: October 2024

Abstract
The monolithic designation of “sphero-conical vessels,” chosen to circumvent the long-standing modern debate around the function of these objects, does not satisfy the multiplicity of terms and uses that they had in the past. A munāẓara (disputation) by Zangi al-Bukhari titled “Dispute between the mavīzāb and the fuqqāʿ of the Iranians” (presented here in full translation) provides new insight into one such use, while also expanding our understanding of everyday life in late thirteenth–early fourteenth-century Baghdad.
Drawing from this Persian work and from Arabic medieval cookery books, this essay connects the physical qualities of drinks and associated etiquettes of consumption to the materiality of surviving objects. Still raisin drinks were ladled from large metal bowls into smaller ones. Earthenware sphero-conical vessels, perhaps a group among those resembling pinecones, were used individually, to gulp down the foam of effervescent drinks.
Selected Phenomena from the Arabic Dialect of the Jews of Damascus
Authors: Matsa Shay 
Published: October 2024

Abstract
This article presents, for the first time, a range of features in Judeo-Damascene (JD), the spoken dialect of the Jews of Damascus, that distinguish it from the common Damascene (CD) dialect of the non-Jewish communities. The article is based on recorded interviews with Damascene Jews. This Jewish dialect is distinct from the Arabic dialect spoken by the Muslim and Christian populations of Damascus not only lexically—in the use of vocabulary from Hebrew and Romance sources—but also in some features of its phonology and morphology. Distinctive forms appear in verbal inflections, pronouns, prepositions, and other morphological categories. The article also compares JD with other Jewish dialects and vernaculars in the Levant and shows some interesting links between JD and Christian Damascene.