bluuebunny/crossref_metadata_2025_split huggingface dataset:
In search of sustainable legitimacy of private firms in China
Authors: Liang Xin , Xiu Lin , Wu Sibin , Zhang Shujuan 
Published: June 2017

PurposePrivate firms in China are like the third child in a family, constantly struggling to establish their position in an environment favoring their state-owned and collective siblings. The purpose of this paper is to discover some long-term-oriented legitimacy building strategies for private firms in China.Design/methodology/approachThis paper examines the effect of both internal and external institutional factors on long-term legitimacy for private enterprises. The authors integrate stakeholder perspective and institutional theory to provide a framework of building sustainable legitimacy.FindingsThe authors’ framework delineates that a private company can build sustainable legitimacy through catering long-term legitimacy conferring to constituents such as customers, social responsibility and patriotism in the external institutional environment.Practical implicationsThe authors’ framework further indicates how private firms could leverage internal institutional environment through developing appropriate mission, culture, leadership and human resources practices in conformity to the demands of constituents for gaining long-term legitimacy.Originality/valueThis paper is the first to address the short-term nature of legitimacy building strategies proposed in the past literature. In addition, it is also the first attempt to explore the multiplicity in legitimacy in China in search of long-term legitimacy building approaches.
Optimization of the reefed parachute using genetic algorithm
Authors: Yang Xue , Yu Li , Zhao Xiao-Shun 
Published: June 2017

Purpose
The purpose of this paper is to find optimal reef parameters to minimize the maximum instantaneous opening load for a reefed parachute with geometry and environmental parameters given in the model.

Design/methodology/approach
The dynamic model Drop Test Vehicle Simulation (DTVSim) is used to model the inflation and descent of the reefed parachute system. It is solved by the fourth-order Runge–Kutta method, and the opening load values are thereby obtained. A parallel genetic algorithm (GA) code is developed to optimize the reefed parachute. A penalty scheme is used to have the maximum dynamic pressure restricted within a certain range.

Findings
The simulation results from DTVSim fit well with experimental data from drop tests, showing that the simulator has high accuracy. The one-stage and two-stage reefed parachute systems are optimized by GA and their maximum opening loads are decreased by 43 and 25 per cent, respectively. With the optimal reef parameters, two of the peaks in the opening load curve are almost equal. The velocity, loiter time and flight path angle of the parachute system all change, but these changes have no negative effect on the parachute’s operational performance.

Originality/value
An optimization method for reefed parachute design is proposed for the first time. This methodology can be used in the preliminary design phase for a reefed parachute system and significantly improve design efficiency.
Investigation of rotating stall characteristics in a centrifugal pump impeller at low flow rates
Authors: Zhou Peijian , Wang Fujun , Mou Jiegang 
Published: June 2017

Purpose
Rotating stall is an unsteady flow phenomenon that causes instabilities and low efficiency in pumps. The purpose of this paper is to investigate the rotating stall characteristics and unsteady behavior of stall cells in a centrifugal pump impeller at low flow rates.

Design/methodology/approach
A developed large eddy simulation with dynamic mixed nonlinear model is performed to evaluate the unsteady flow in a centrifugal pump impeller. The rotating stall flow field through the centrifugal pump impeller is analyzed under three typical flow rates. Frequency spectrum analysis are carried out on the series of pressure fluctuation to get the rotating stall characteristics. The size and intensity of stall cells are also analyzed using time-averaged vorticity and static pressure.

Findings
The rotating stall cell first occurs in the suction side of the blade and exhibits an obvious life cycle including decay mergence, shedding, growing and development with a low frequency. With the decrease of flow rate, the amplitude of pressure fluctuations in the impeller tends to be larger, the propagated speed of stall cells and rotating stall frequency tends to be smaller, but the number of cells remains unchanged. The size of stall cells increases as the flow rate decreases, but intensity changes is very little.

Originality/value
The rotating stall characteristics in a centrifugal pump impeller under low flow rates are presented first using a developed large eddy simulation approach.
All that glitters is not gold
Authors: Church Allan H. , Del Giudice Matthew , Margulies Alyson 
Published: June 2017

Purpose
Formal assessment and development of executives have become standard practices in organizations. There is a need, however, to determine what levers are available to maximize the impact and return on investment of initiatives. The purpose of this paper is to present outcomes and learnings from a multi-method approach to evaluating behavior change following the implementation of PepsiCo’s Senior Leader Development Center, a comprehensive process designed to accelerate capability at the executive level.

Design/methodology/approach
Learnings are presented based on analyses from three independent data sources collected throughout the 18-month program: behavioral change ratings from managers, direct reports, and peers via a 360 survey; attitudinal measures from participants’ post-program completion; and third-party observations by an internal facilitator.

Findings
Overall, findings indicate that while program rigor and content do matter as baseline components, principles of participant engagement and commitment emerged as most essential to delivering programs with sustained impact.

Research limitations/implications
This case is based on leaders in a high-touch multi-trait multi-method assessment and development program in one organization. Additional research is needed to explore in other settings.

Practical implications
Results and implications are organized by each of the four key stages of the assessment and development process: conduct data-based assessments, deliver feedback and insights, build the development plan, and take action to implement the plan. Findings and recommendations for practice regarding each stage are discussed.

Originality/value
Few case studies or applied research exist that focus on the execution and outcomes associated with senior executive assessment and development programs in major corporations. This paper offers findings regarding the overall impact of such a program and key learnings from its sustained effort in a complex multi-national organization. The discussion and implications in this paper may directly influence how other organizations design and manage future talent management interventions with similar types of senior-level populations.
An integrative model of trust and leadership
Authors: Hasel Markus C. , Grover Steven L. 
Published: June 2017

PurposeThe purpose of this paper is to examine the interplay between different streams of trust and leadership and their impact on motivation and performance. The model answers recent calls for a better understanding of underlying mechanisms in these interactions.Design/methodology/approachThe authors drew from contemporary leadership and trust theories to develop ten propositions teasing out how specific person- and role-oriented leadership behaviors interact with calculus-, identification-, knowledge-based trust, motivation, and performance.FindingsThe model accentuates the complexity of the interactions between trust, leadership, and follower outcomes. It guides future empirical research to unravel these intricate relations and accentuates their complexity.Research limitations/implicationsThe ten propositions act as guidelines in mastering the complex art of leadership by understanding how behaviors affect followers. An important limitation originates in the detailed analysis of leadership and trust. Focusing on specific leadership behaviors and trust types leaves further scope for future research into additional behaviors and cofounding variables to arrive at a more holistic picture of the underlying mechanisms that make or break an effective leader.Originality/valueContemporary theories on leadership and trust frequently view the different streams as overall constructs in lieu of multi-faceted phenomena. The model is a first of its kind in that it fuses contemporary leadership and trust theory to develop a set of propositions based on specific interactions between leadership behaviors and different forms of trust.
Pharmacokinetics and pharmacodynamics of bococizumab, a monoclonal antibody to PCSK9, after single subcutaneous injection at three sites [NCT 02043301]
Authors: Wang Ellen Q. , Plotka Anna , Salageanu Joanne , Sattler Catherine , Yunis Carla 
Published: June 2017

SummaryAimTo characterize the single‐dose pharmacokinetics (PK) and pharmacodynamics (PD) of bococizumab, a monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9), administered subcutaneously (s.c.) to the abdomen, thigh, or upper arm (NCT02043301).MethodsSeventy‐five adults with low‐density lipoprotein cholesterol (LDL‐C) ≥130 mg/dL and not on background lipid‐lowering therapy were randomized (1:1:1) to a single 150‐mg s.c. dose of bococizumab administered to the abdomen, thigh, or upper arm. Blood samples for bococizumab and lipids were collected for 12 weeks postdose.ResultsPlasma bococizumab concentration‐time profiles and PK parameters were generally similar across injection sites. Mean maximum observed concentration (Cmax) ranged from 8.14 to 11.9 μg/mL, and area under the concentration‐time curve (AUCinf) ranged from 160.3 to 198.9 µg∙day/mL. The median time to Cmax (Tmax) ranged from 4.25 to 6.93 days. Similar LDL‐C concentration‐time profiles were observed across injection sites, with mean (% coefficient of variation) maximum reductions in LDL‐C of −57.5% (15.8), −57.0% (25.9), and −55.0% (24.1) for the abdomen, thigh, and upper arm, respectively. Adverse events (AEs) were mostly mild and generally similar across injection sites. Commonly reported AEs were upper respiratory tract infection (9.3%), headache (6.7%), and injection site reaction (6.7%). One serious AE was reported (ischemic colitis), which was not considered related to study drug.ConclusionsSimilar PK profiles and robust LDL‐C reductions were observed following a single 150‐mg s.c. injection of bococizumab administered to the abdomen, thigh, or upper arm in untreated subjects with LDL‐C ≥130 mg/dL. Bococizumab was generally well tolerated following a single 150‐mg s.c. administration in this subject population.
Laparoscopic surgery for sigmoid colon cancer after multiple operations including urinary diversion with Indiana pouch: A case report
Authors: Iwamoto Kazuya , Takahashi Hidekazu , Haraguchi Naotsugu , Nishimura Junichi , Hata Taishi , Matsuda Chu , Yamamoto Hirofumi , Mizushima Tsunekazu , Doki Yuichiro , Mori Masaki 
Published: June 2017

AbstractA 73‐year‐old man with lower abdominal pain was diagnosed at our hospital with sigmoid colon cancer. He had previously undergone radical cystectomy with Indiana pouch construction and gastrectomy to treat bladder cancer and gastric cancer, respectively. We performed a laparoscopic Hartmann's operation with Japanese D3 lymph node dissection. We observed severe adhesion in the abdominal cavity; adhesions between the urostomy and sigmoid colon were particularly severe. The tumor had invaded to the distal rectum, which had adhered to the pubic bone and the previously reconstructed urinary pouch. By performing careful and persistent laparoscopic dissection, we completed the operation without damaging the urostomy and with no remnant tumor tissue (R0). The postoperative course was uneventful, and the patient was doing well with no evidence of cancer recurrence 1 year after surgery.
Increased renal concentrating ability after long‐term oral desmopressin lyophilisate treatment contributes to continued success for monosymptomatic nocturnal enuresis
Authors: Ikeda Hirokazu , Watanabe Tsuneki , Isoyama Keiichi 
Published: June 2017

ObjectivesTo investigate renal concentrating ability after long‐term fast‐melting oral desmopressin lyophilisate treatment in children with monosymptomatic nocturnal enuresis.MethodsThe present retrospective study involved 58 children (43 boys, 15 girls; aged 6–12 years) with nocturnal enuresis receiving oral desmopressin lyophilisate. After treatment for 4 weeks with a complete response, patients were placed on a reduced dose of 120 μg on alternate days. Moring urine osmolality was measured using urine samples obtained after medication and non‐medication dry nights. Patients who experienced ≥1 wet nights/month during alternate‐day oral desmopressin lyophilisate treatment or within 6 months after its cessation were assigned to the relapse group, whereas those who experienced <1 wet night/month were assigned to the continued success group.ResultsThe continued success and relapse groups included 41 and 17 patients, respectively. The mean duration of treatment was 18.5 and 18.3 months in the continued success group and relapse group, respectively. There was no significant difference in morning urine osmolality after medication nights between the continued success and relapse groups; however, morning urine osmolality after non‐medication nights was significantly higher in the continued success group than in the relapse group (P < 0.0001). Similarly, nocturnal urine volume was significantly higher in the relapse group than in the continued success group (P = 0.046).ConclusionsThese results suggest that patients receiving long‐term oral desmopressin lyophilisate treatment develop increased nocturnal renal concentrating ability, which results in sustained dryness even after treatment cessation.
Recent progress in immunotherapy for urological cancer
Authors: Obara Wataru , Kato Renpei , Kato Yoichiro , Kanehira Mitsugu , Takata Ryo 
Published: June 2017

AbstractCancer immunotherapy for urological tumors had made progress for several decades, but recent advances in immunotherapy, as therapeutic vaccines or immune checkpoint inhibitors, have drastically changed the present treatment strategy. Recently, nivolumab and atezolizumab have been approved by the Food and Drug Administration for treatment of urological cancers. Additional immune checkpoint inhibitors and vaccines are being tested in clinical trials. Despite advances in these therapeutic modalities, benefits are limited to a subset of patients. New agents and novel combinations will also continue to create new immunotherapy strategies. Further development of biomarkers for predicting response is required to achieve optimal efficacy with these therapeutic interventions.
Optimal policy and the role of social contacts in a search model with heterogeneous workers
Authors: Stupnytska Yuliia , Zaharieva Anna 
Published: June 2017

AbstractThis paper develops a search model with heterogeneous workers and social networks. High‐ability workers are more productive and have a larger number of professional contacts. Firms can choose between a vacancy in the regular market and a job opening in the referral market. The model predicts that a larger number of social contacts is associated with a larger wage gap between high‐ and low‐ability workers and a larger difference in the unemployment rates. The net welfare gain of referrals is estimated at 1.2%. There are three reasons for the inefficiency of the decentralized equilibrium. First is the traditional search externality described by Hosios. Second, firms share their profits with workers, whereas the social optimum implies that full surplus should be given to firms in the referral market. This inefficiency can be internalized by means of referral subsidies. Third, there is the “pooling inefficiency” in the regular market. If high‐ability workers are sufficiently more productive they impose a positive externality on low‐ability workers and should be rewarded by positive transfers. On the contrary, if productivity differences are small, high‐ability workers achieve unreasonably high wages by referring each other and reduce employment chances of low‐ability workers. In this latter case, high‐ability workers should be penalized. If optimal policy is implemented the net welfare gain of referrals rises up to 1.8%.
A case of presumed autoimmune subepidermal blistering dermatosis treated with oclacitinib
Authors: Aymeric Estelle , Bensignor Emmanuel 
Published: June 2017

BackgroundAutoimmune subepidermal blistering dermatoses (ASBD) are a group of severe autoimmune dermatoses rarely described in dogs. Their treatment usually necessitates the long term use of medications potentially associated with adverse effects. In humans, Janus Kinase (JAK) inhibitors have been demonstrated to be of value in some cases of autoimmune skin disease.Hypothesis/ObjectivesTo evaluate oral oclacitinib, a JAK‐1 predominant inhibitor, in one case of ASBD in a dog.Case reportA 5‐year‐old German shepherd cross‐bred dog was presented with an acute onset of ulcerative and blistering skin lesions on the face, oral cavity, lateral trunk and limbs. Associated systemic signs were not seen. A clinical diagnosis of ASBD was supported by the finding of subepidermal clefts and visualization of the epidermal basement membrane zone at the bottom of the clefts on histopathological examination. Treatment was initiated with prednisolone at 1.2 mg/kg twice daily. Because of severe adverse effects and relapse, when the prednisolone dose was reduced, oclacitinib therapy was administered at 0.5 mg/kg twice a day. A complete resolution of clinical signs was noted after one month and no relapse was observed after twelve months of treatment. No adverse effects were reported.ConclusionThe use of oclacitinib may be useful for the treatment of some autoimmune skin diseases in dogs. Further controlled studies are needed to confirm our findings.
Mobile-assisted Language Learning (MALL) for ESL Learners: A Review of Affordances and Constraints
Authors: Hashim Harwati , Md. Yunus Melor , Amin Embi Mohamed , Mohamed Ozir Nor Azwa 
Published: June 2017

Nowadays, mobile technology is changing the landscape of language learning and is seen as the next frontier being researched for its potential in enhancing the teaching and learning of English language. The portability of mobile devices is believed to bring new methods that can shape learning styles and pedagogies which could become more personalised and allow learners to learn on the move; thus, enhance English language teaching and learning. This creates the potential for significant change in the teaching and learning of English as Second Language (ESL). Taking mobile learning as the setting within which developments in Mobile-assisted Language Learning (MALL) may be understood, this paper offers reflections on what Mobile-assisted Language Learning (MALL) has potentially offered and the constraints that might be faced by the English as Second Language (ESL) learners when using MALL. Above all, it was a challenging issue to cover learning tasks by using a mobile device particularly in learning English as Second Language (ESL). Nevertheless, mobile devices which are popular among students are motivational tools to be used in education as well as various learning activities. This was proven by many researchers who have shown the positive outcomes. Hence, we should admit that mobile devices are finding their way into classrooms in the student’s pockets, and we have to ensure that educational practice can include this mobile technology in effective and productive ways particularly for English as Second Language (ESL) learning.
Sīrah Of The Prophet’s Early Life In Musnad of Aḥmad: An Analytical Study Of Qurʿānic References In Sīrah Nabawiyyah
Authors: Azmi Ahmad Sanusi 
Published: June 2017

Reviews of early Muslim sources confirm that some verses of the Qur’ān have been perceived by Muslim scholars as direct references to the narratives of the Prophet’s early life. These selected verses are deemed to contain information about Muḥammad’s genealogy, birth, childhood and other aspects of his youth. Modern scholars have, however, argued about the appropriateness and authority of these Qur’ānic references as being the true bearers of information of the Prophet’s biography. Since the ḥadīth is regarded as an authoritative exegetical tool employed to explore more deeply the meaning of the Qur’ān, and one of which contains a vast source of information about the Prophet’s life, it is indispensable to analyse the works of ḥadīth and its scholars’ views on the narratives of sīra nabawiyya. This study aims to explore the narratives of the Prophet’s early life in Musnad of Aḥmad and analyse Aḥmad’s perspective regarding Quranic references to the Prophet’s early life. The study is qualitative in nature in which the researcher utilised both critical and analytical approached as its methodology. The study in its finding espouses that the rarity of Qur’ānic reference to Muḥammad’s early life in Musnad of Aḥmad, an enormous inventory of ḥadīth of the ninth century, indicates one scholar’s views about Muḥammad’s early life. It is obvious that Aḥmad make no connection between the Quran and the narratives of the Prophet’s early life, even though verses that are widely used by the author of sīra as an allusion to Muḥammad’s early life.