bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low and high dietary folic acid levels perturb postnatal cerebellar morphology in growing rats
Authors: Partearroyo Teresa , Pérez-Miguelsanz Juliana , Peña-Melián Ángel , Maestro-de-las-Casas Carmen , Úbeda Natalia , Varela-Moreiras Gregorio 
Published: April 2016

AbstractThe brain is particularly sensitive to folate metabolic disturbances, because methyl groups are critical for brain functions. This study aimed to investigate the effects of different dietary levels of folic acid (FA) on postnatal cerebellar morphology, including the architecture and organisation of the various layers. A total of forty male OFA rats (a Sprague–Dawley strain), 5 weeks old, were classified into the following four dietary groups: FA deficient (0 mg/kg FA); FA supplemented (8 mg/kg FA); FA supra-supplemented (40 mg/kg FA); and control (2 mg/kg FA) (alln10 per group). Rats were fedad libitumfor 30 d. The cerebellum was quickly removed and processed for histological and immunohistochemical analysis. Slides were immunostained for glial fibrillary acidic protein (to label Bergmann glia), calbindin (to label Purkinje cells) and NeuN (to label post-mitotic neurons). Microscopic analysis revealed two types of defect: partial disappearance of fissures and/or neuronal ectopia, primarily in supra-supplemented animals (incidence of 80 %,P≤0·01), but also in deficient and supplemented groups (incidence of 40 %,P≤0·05), compared with control animals. The primary fissure was predominantly affected, sometimes accompanied by defects in the secondary fissure. Our findings show that growing rats fed an FA-modified diet, including both deficient and supplemented diets, have an increased risk of disturbances in cerebellar corticogenesis. Defects caused by these diets may have functional consequences in later life. The present study is the first to demonstrate that cerebellar morphological defects can arise from deficient, as well as high, FA levels in the diet.
Milk fat globule membrane coating of large lipid droplets in the diet of young mice prevents body fat accumulation in adulthood
Authors: Baars Annemarie , Oosting Annemarie , Engels Eefje , Kegler Diane , Kodde Andrea , Schipper Lidewij , Verkade Henkjan J. , van der Beek Eline M. 
Published: April 2016

AbstractEpidemiological studies have demonstrated protective effects of breast-feeding on childhood obesity. Differences between human milk and infant milk formula (IMF) in dietary lipid structure may contribute to this effect. In our mouse model, feeding a diet containing large lipid droplets coated with phospholipids (PL) (Nuturis®; PL of milk fat globule membrane (MFGM) fraction origin) in early life protected against excessive body fat accumulation following a diet challenge in adult life. We now set out to determine the relevance of increased droplet size and/or MFGM lipid droplet coating to the observed anti-obesogenic effects in adult life. From day 16 to 42, male mouse pups were exposed to diets with small (S) or large (L) lipid droplets (0·3 v. 2·9 µm average mode diameter, respectively), either without MFGM or with MFGM coating around the lipid droplet, resulting in four groups: S (control diet), L, Scoating and Lcoating (Nuturis® IMF diet). Mice were subsequently challenged with a Western-style diet until dissection at postnatal day 98. A non-challenged group served as reference (REF). We repeatedly determined body composition between postnatal day 42 and 98. At day 98 plasma and gene expression measurements were performed. Only the Nuturis® IMF diet (Lcoating) in early life containing MFGM-coated large lipid droplets reduced body fat mass to a level comparable with the REF group. These data support the notion that the structural aspects of lipids in human milk, for example, both lipid droplet size as well as the MFGM coating, may contribute to its reported protective effect against obesity in later life.
A sporomorph ecogroup model for the Northwest European Jurassic - Lower Cretaceous II : Application to an exploration well from the Dutch North Sea
Authors: Abbink O.A. , Van Konijnenburg-Van Cittert J.H.A. , Van der Zwan C.J. , Visscher H. 
Published: April 2016

AbstractJurassic shallow marine to non-marine depositional sequences are among the most important economic targets in the North Sea. Detailed, ‘high resolution’ stratigraphy of these sequences has become a necessity in both predictive geological exploration models as well as in production reservoir models. In these paralic sequences, palynomorphs are the most abundant (micro) fossil group. Palynology is increasingly challenged to improve the biostratigraphic control, and to support the sequence stratigraphical framework. Based on a recently developed, conceptual Sporomorph EcoGroup model, the quantitative distribution patterns of terrestrial palynomorphs are grouped in six Sporomorph EcoGroups (SEGs), viz. Upland, Lowland, River, Pioneer, Coastal, and Tidally-influenced SEG. Application of the SEG model to data from a marginal marine, uppermost Callovian - Middle Oxfordian section of NAM well F17-4 from the southern part of the Central North Sea Graben allows the recognition of sea-level fluctuations and climate changes. A marked palaeoclimatic shift occurred in the earliest Middle Oxfordian. The relatively cool-subtropical, humid climate changed into a warmer, subtropical-tropical, drier climate. The sea-level reconstructions based on the SEG model are validated against a latest Callovian - Earliest Oxfordian depositional sequence.
New subsurface temperature maps for the Tertiary Lower Rhine Basin and the adjacent Variscan Basement - Germany, The Netherlands, Belgium
Authors: Karg H. , Bücker C. , Schellschmidt R. 
Published: April 2016

AbstractThe regional subsurface temperature field at the transition between the Palaeozoic Variscan Basement and the Cenozoic Lower Rhine Basin in Dutch, German and Belgium territories was mapped up to a depth of 1000 m. Temperature data from 66 wells and 11 coal mine subcrops were available. In 46 wells, temperature logs, covering a cumulative depth interval of 6600 m, were measured for this study.
Reservoir characterisation using process-response simulations: the Lower Cretaceous Rijn Field, West Netherlands Basin
Authors: Alberts L.J.H. , Geel C.R. , Klasen J.J. 
Published: April 2016

AbstractPetroleum geologists always need to deal with large gaps in data resolution and coverage during reservoir characterisation. Seismic data show only large geological structures, whereas small-scale structures and reservoir properties can be observed only at well locations. In the area between wells, these properties are often estimated by means of geostatistics. Numerical simulation of sedimentary processes offers an alternative method to predict these properties and can improve the understanding of the controls on reservoir heterogeneity. Although this kind of modelling is widely used on basin scale in exploration geology, its application on field scale in production geology is virtually non-existent. We have assessed whether the recent developments in numerical modelling can also aid petroleum geologists in the interpretation of the reservoir geology.Seismic data, well data and a process-response model for coastal environments were used to characterise the Lower Cretaceous oil-bearing Rijn Field. Interpretation of seismic and well data led to a definition of the structural setting and the depositional model of the Rijn Member in the area. From the sedimentological interpretation the sea-level history could be estimated, which is the one of the most important input parameters for the process-response model.Application of the process-response simulator to the Rijn Field resulted in approval of the depositional model. The output was presented in a 2-dimensional north-south profile, which corresponds very well to the well logs along this section. The results demonstrate that numerical simulations of geological processes can be very useful as a tool to explore many likely geological scenarios. While it cannot be used to supply a unique solution in many cases, it forms a helpful guide during reservoir characterisation to find an optimal scenario of the controls on deposition of the Rijn Member, which contributes to the understanding of the inter-well reservoir heterogeneity.
Restoration of former wetlands in the Netherlands; effect on the balance between CO2 sink and CH4 source
Authors: van den Bos R. 
Published: April 2016

AbstractDrained coastal peatlands are a source of greenhouse gas (GHG) through abundant CO2 release caused by aerobic peat degradation. Published rates of CO2 fixation and CH4 release for natural peatlands suggest that areas of peat formation are a (small) net source of GHG emission because the radiative effect of emitted CH4 exceeds the CO2 uptake by the vegetation. It is shown here that wetland restoration of reclaimed peat areas in the western Netherlands leads to a reduction of GHG emission because the expected increase in anaerobically generated CH4 release is much smaller than the decrease in aerobically produced CO2.
Redeposited chalk hydrocarbon reservoirs of the North Sea caused by the Chicxulub K-T bolide impact
Authors: Rider M. , Kroon D. 
Published: April 2016

AbstractA widespread, slumped, redeposited, uppermost Cretaceous chalk interval, up to 60m thick, immediately below the Cretaceous-Tertiary (K-T) boundary, recognised in oil company boreholes across the central North Sea and a major hydrocarbon reservoir, we re-interpret as the result of a single, catastrophic event caused by secondary effects related to the bolide impact at Chicxulub. A thin, dark clay bed immediately above the redeposited chalks, we suggest correlates to the outcropping, Iridium rich, Danish ‘Fish Clay’, rapidly deposited after the impact. Physical effects on sea-floor sediments, caused by the K-T bolide impact, have not previously been interpreted in the North Sea.
Stratigraphic architecture of the Upper Cretaceous and Cenozoic along the
southern border of the North Sea Basin in Belgium
Authors: Vandenberghe N. , Van Simaeys S. , Steurbaut E. , Jagt J.W.M. , Felder P.J. 
Published: April 2016

Abstract
The Late Cretaceous and Cenozoic sedimentary record in the Campine Basin
along the southern border of the North Sea Basin is analysed in terms of
sequence stratigraphy. All available biostratigraphic, and in some cases,
magnetostratigraphic data are used to constrain the sequence
chronostratigraphy. The relative geographic extent of the strata is used as
an indication of the relative sea level. Tectonic and eustatic components
could be distinguished in several cases using regional geological
information. Generally, sequences consist of transgressive and highstand
systems tracts only and have flat, abrasion-type lower boundaries. Lowstand
deposits are only identified as infill of erosional space, which generally
implies marked tectonic uplift. Several eustatic and tectonic events can be
correlated with similar events known elsewhere in the North Sea Basin. The
time intervals spanned by the different sequences vary considerably,
pointing out different control mechanisms.
Stable oxygen isotope record of the Eocene-Oligocene transition in the
southern North Sea Basin: positioning the Oi-1 event
Authors: De Man E. , Ivany L. , Vandenberghe N. 
Published: April 2016

Abstract
Preliminary stable oxygen isotope data are presented from the southern
North Sea Basin successions, ranging from the Lutetian to Rupelian. Analyses
were performed on fish otoliths, nuculid bivalves and benthic foraminifera
and are presented as bulk δ18O values relative to a
well established regional sequence stratigraphic framework. The most
significant positive shift in δ18O values clearly falls
at the top of the regionally recognised Bassevelde 3 sequence, which base
corresponds to the Eocene-Oligocene GSSP boundary. The here documented
δ18O shift is closely associated with the base of
the traditional Rupelian unit-stratotype and is tentatively correlated to
the globally recognised Oi-1 event.
Late Oligocene Warming Event in the southern North Sea Basin: benthic foraminifera as paleotemperature proxies
Authors: De Man E. , Van Simaeys S. 
Published: April 2016

AbstractThe investigation of foraminiferal assemblages from a series of Oligocene borehole sections allowed paleoenvironment and paleoclimate reconstructions for the Rupelian and Chattian (Lower and Upper Oligocene) Stages in their type region, the southern North Sea Basin. A striking feature coinciding with the Rupelian-Chattian (R-C) unconformity is the major change in paleotemperature and paleobathymetry. The shallow marine to restricted marine subtropical fauna at the base of the Chattian is in strong contrast with the deeper marine and cooler upper Rupelian assemblages. This study suggests that the early Chattian transgression is genetically related to a widespread major warming pulse, known as the Late Oligocene Warming Event.
A new Ordovician astylospongiid sponge (Porifera) as an erratic from Baltica
Authors: Rhebergen F. 
Published: April 2016

AbstractUntil now hemispherical astylospongiid sponges were invariably referred to as Caryospongia juglans var. basiplana Rauff. Renewed investigations have now shown that part of the material should be assigned to a new genus and species, Tympanospongia vankempeni, which is characterised by a system of very irregular canals. These flat-based sponges originate from the Baltic region and occur in two assemblages of silicified Late Ordovician sponges known exclusively as erratics from The Netherlands and northern Germany. These fossils were transported by the River Eridanos, a former drainage system from the Baltic region that filled the North European Basin during the Miocene to Early Pleistocene. Specimens of Tympanospongia vankempeni gen. et sp. nov. also occur in the Upper Pleistocene of Gotland, Sweden. The new sponge described herein principally differs from other genera of the Astylospongiidae found frequently in the erratic sponge assemblages by its irregular system of apochetes which ramify and anastomose commonly.
A southern North Sea Miocene dinoflagellate cyst zonation
Authors: Munsterman D.K. , Brinkhuis H. 
Published: April 2016

AbstractAn integrated stratigraphical analysis emphasizing organic-walled dinoflagellate cyst (dinocyst) distribution has been carried out on multiple boreholes penetrating the Miocene in the subsurface of the Netherlands (southern North Sea Basin). The bulk of the investigated successions is attributed to the Breda Formation, a regional lithostatigraphical unit most complete in the south-eastern part of the Netherlands. In concert with a first regional integrated bio (chrono) sequence-stratigraphical framework, fourteen informal dinocyst zones for the southern North Sea Miocene (SNSM), and three subzones are proposed for the Breda Formation. By also integrating (chrono)stratigraphic information from Mediterranean and North Atlantic dinocyst studies a first ever detailed age-model is here proposed for the Miocene in the subsurface of the Netherlands.
A sporomorph ecogroup model for the Northwest European Jurassic - Lower Cretaceousi: concepts and framework
Authors: Abbink O.A. , Van Konijnenburg-Van Cittert J.H.A. , Visscher H. 
Published: April 2016

AbstractBased on recent vegetation distribution and an integration of macropalaeobotanical and palynological information, a palaeocommunity model is explored that may permit detailed interpretations of quantitative sporomorph distribution patterns in the Jurassic and Early Cretaceous of NW-Europe in terms of changes in palaeoenvironment (sea-level, climate). The conceptual model is based on the recognition of Sporomorph Ecogroups (SEGs) that reflect broad co-existing plant communities, viz. upland, lowland, river, pioneer, coastal, and tidally-influenced SEGs. In successive palynological assemblages, shifts in the relative abundance of SEGs are thought to be indicators of sea-level changes. Climatic changes may be recognised through significant shifts within the quantitative composition of individual SEGs.
Marine Miocene deposits in the Maaseik well 49W/220 in eastern Belgium: biostratigraphy by means of various microfossil groups.
Authors: Hooyberghs H. , Wouters K. , Spiegler D. 
Published: April 2016

AbstractA micropalaeontological analysis (foraminifera, ostracoda andbolboforma)has been undertaken for the interval between 299.7 and 201.5m of the Maaseik borehole. This interval includes marine glauconitic sands, which are generally not or not strongly decalcified. Independent from each other, the observed taxa of the different microfossil groups indicate a Late (range down to Middle) Miocene age for the interval. On the base of the biozonations of the various microfossil groups, some correlations can be presented with Late Miocene deposits of other areas in Belgium (Antwerp and Campine area), and of other places in NW Europe.
Faults in the Asquempont area, southern Brabant Massif, Belgium
Authors: Debacker T.N. , Herbosch A. , Verbiers J. , Sintubin M. 
Published: April 2016

AbstractThe literature suggests that the Asquempont fault, a supposedly important reverse fault forming the limit between the Lower to lower Middle Cambrian and the Ordovician in the Sennette valley, is poorly understood. Nevertheless, this fault is commonly equated with a pronounced NW-SE-trending aeromagnetic lineament, the Asquempont lineament, and both the geometry of the Asquempont lineament and the supposed reverse movement of the Asquempont fault are used to develop large-scale tectonic models of the Brabant Massif. New outcrop observations in the Asquempont area, the “type locality” of the Asquempont fault, in combination with outcrop and borehole data from surrounding areas, show that the Asquempont fault is not an important reverse fault, but instead represents a pre-cleavage, low-angle extensional detachment. This detachment formed between the Caradoc and the timing of folding and cleavage development and is not related to the aeromagnetic Asquempont lineament. The Asquempont area also contains several relatively important, steep, post-cleavage normal faults. Apparently, these occur in a WNW-ESE-trending zone between Asquempont and Fauquez, extending westward over Quenast towards Bierghes. This zone coincides with the eastern part of the WNW-ESE-trending Nieuwpoort-Asquempont fault zone, for which, on the basis of indirect observations, previously a strike-slip movement has been proposed. Our outcrop observations question this presumed strike-slip movement. The Asquempont fault may be related to the progressive unroofing of the core of the Brabant Massif from the Silurian onwards. Possibly, other low-angle extensional detachments similar to the Asquempont fault occur in other parts of the massif. Possible candidates are the paraconformity-like contacts depicted on the most recent geological map of the Brabant Massif.
A new record of Clidastes (Squamata, Mosasauridae) from the Upper Campanian of the Münster Basin (NW Germany)
Authors: Diedrich C. , Mulder E.W.A. 
Published: April 2016

AbstractFrom Upper Campanian turbiditic marls at Beckum in the Münster Basin (NW Germany) the anterior portion of a mosasaurid premaxilla with abutting fragments of the left and right maxilla is described and referred to the genus Clidastes. It shows the process of tooth replacement very well. This taxon is recorded for the first time from Germany. Clidastes co-existed in central Europe with other mosasaurids such as representatives of the genus Leiodon and Mosasauridae indet.
The Pleistocene College Farm Silty Clay at Great Blakenham, Suffolk, England – additional information on the course of the early River Thames
Authors: Moorlock B.S.P. , Riding J.B. , Hamblin R.J.O. , Allen P. , Rose J. 
Published: April 2016

AbstractThe Pleistocene College Farm Silty Clay Member of the Creeting Formation at Great Blakenham, Suffolk, south-east England is shown to contain indigenous and recycled dinoflagellate cysts and other derived palynomorphs. The indigenous dinoflagellate cysts indicate a marine influence during deposition of the clay, whilst the other palynomorphs demonstrate derivation of sediment from a wide catchment of Carboniferous, Jurassic and Cretaceous bedrocks. It is argued, by comparison with palynological data from the Chillesford Clay Member of the Norwich Crag Formation some 25km to the east, that these sediments were eroded from western, south-central and south-eastern Britain, and transported by the early River Thames to its estuary, where they were redeposited at the western margin of the Crag Basin, during the Early Pleistocene Tiglian TC3 Substage. This interpretation refines earlier research which concluded the College Farm Silty Clay was deposited in a predominantly freshwater environment, such as a lagoon, without any direct access to the sea or major river.
Internal structure and development of an aeolian river dune in The Netherlands, using 3-D interpretation of ground-penetrating radar data
Authors: Van Dam R.L. 
Published: April 2016

AbstractGround-penetrating radar data from a regular grid are used to study the internal structure and development of a 9-m high aeolian river dune in the Dutch Rhine-Meuse delta. The purpose of this investigation was to image the internal sedimentary structures to better understand the development of these aeolian river dunes. Three radar facies can be recognised in the GPR sections. Radar facies 1 has a maximum thickness of 5 to 6 m and is characterised by dipping, parallel reflections with a maximum length of at least 20 m. The reflections from perpendicular sections, analysed using closed-loop correlation in 3-D-interpretation software, form eastward dipping (14°maximum) surfaces. Radar facies 2 is one continuous, sub-horizontal reflection. This high amplitude reflection is most probably caused by a thin organic horizon. Radar facies 3 has a thickness of 3 to 4 m and is made up of sets of short, predominantly eastward to north-eastward dipping reflections separated by rather continuous, sub-horizontal reflections. The eastward dipping surfaces in radar facies 1 are foresets of a dune that was deposited by prevailing westerly winds in the Younger Dryas, the last cold period in the Pleistocene. During the Early Holocene, an increasing vegetation cover stabilised the dune and formed a thin organic horizon. Subsequent resumption of dune forming processes led to the formation of radar facies 3 on top of the vegetated Pleistocene dune. Sedimentation by small dunes, partly eroding each other, led to sets of cross-stratification separated by bounding surfaces. The results suggest a small change in palaeo wind direction.
Soil formation in Late Glacial Meuse sediments related to the Peel Boundary Fault activity
Authors: Miedema R. , Jongmans T. 
Published: April 2016

AbstractMicromorphological studies relating the soil formation history (processes and timing) to activity events of the Peel Boundary Fault (PBF) showed rotation features (circular distribution pattern of sand grains) in mechanically displaced rounded fragments of Bt bands. These features are interpreted as being caused by ‘mudflow’ during active faulting event (PBF event F2). The micromorphological interpretation of Late Weichselian soil formation (clay illuviation, degradation features and offsetting of Bt bands) agrees with the hypothesized 3 PBF periods of fault activity events (Fl, F2 and F3).