bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development, education, and services in children with Down syndrome: a cohort analysis from a clinical database
Authors: Soccorso Cara , Hojlo Margaret , Pawlowski Katherine , Lombardo Angela , Davidson Emily , Sargado Sabrina , DePillis Rafael , Baumer Nicole 
Published: October 2024

BackgroundPrior research has characterized neurodevelopmental phenotypes for Down syndrome (DS), but there is variability in age of milestone attainment and limited identification of early predictors of developmental trajectories. Additionally, less is known about receipt of education and services in relation to development.ObjectiveThis study describes the delivery of education and therapies in the setting of general developmental and behavioral needs in a large clinical cohort of children with DS seen in a specialized Down Syndrome Program (DSP).MethodThe clinically collected data included 814 patients with DS who were seen at a specialty DSP at a large, tertiary pediatric care center from March 2018 to January 2023. Data were collected through caregiver-and clinician-reported history at clinical visits to the program. Descriptive frequencies were utilized to describe participant demographics, skills and behaviors, and receipt of services, across age groups in childhood.ResultsDelays were present across all developmental domains; in particular delays in language, communication, and academic skills, and behavioral challenges were commonly reported. Almost all children received Early Intervention (EI) services, and many young children received non-public therapies after completing EI. Older participants demonstrated more impairments than younger age groups, yet received services at lower rates, particularly behavioral and speech language interventions.ConclusionA snapshot of developmental skill attainment in individuals with DS is provided. Therapies to support the levels of need were reported at much lower frequencies than the level of need reported to target aspects of development and behavior. Several gaps in therapies and educational services were identified. There is an important need for tailoring supports, based on developmental level, to meet individual needs. These findings may help to inform policy change related to developmental and educational services for individuals with DS.
Relationship between emotional intelligence and quality of healthcare among nurses
Authors: Oweidat Islam , Alzoubi Mahmoud , Shosha Ghada Abu , Ta’an Wafa’a , Khalifeh Anas , Alzoubi Majdi M. , Al-Mugheed Khalid , Alabdullah Amany Anwar Saeed , Abdelaliem Sally Mohammed Farghaly 
Published: October 2024

IntroductionHealthcare organizations worldwide face intense competition for survival in an ever-changing environment.ObjectivesThis study aims to examine the relationship between emotional intelligence (EI) and quality of healthcare (QHC) among Jordanian nurses working in governmental hospitals.MethodThis study was conducted using a descriptive correlational design and included a sample of 172 nurses. Participants from five governmental hospitals in Jordan completed online self-administered questionnaires, including the Nurse-Assessed Quality of Nursing Care Scale and the Genos Emotional Intelligence Concise Scale, along with sociodemographic data.ResultsThe participating nurses demonstrated a high level of EI (M = 3.809, SD ± 0.484) and a very high level of QHC (M = 4.260, SD ± 0.372). A statistically significant correlation was found between the total quality of healthcare variables and the total EI variable (r = 0.739, p &lt; 0.01). Additionally, statistically significant correlations were observed between the QHC and EI, as well as their respective dimensions (r = 0.357–0.739). EI was found to be a significant predictor of the QHC (F = 34.872, p ≤ 0.001), with a positive correlation between the two variables (r = 0.733). EI accounted for 59.8% of the variation in the QHC.ConclusionEI is a key predictor of QHC. It plays an essential role in recruiting, staffing, promoting, and nurturing employees, making it a crucial criterion for achieving excellence in healthcare organizations.
Response to treatment with grapiprant as part of a standard multimodal regimen in young dogs with appendicular joint osteoarthritis associated pain
Authors: Enomoto Masataka , Hash Jonathan , Cole Tracey , Porcel Sanchez Maria D. , Thomson Andrea , Perry Erin , Aker Savannah , Nakanishi-Hester Aoi , Haupt Emily , Opperman Logan , Roe Simon , Thompson Nichola Archer , Innes John F. , Lascelles Benedict Duncan Xavier 
Published: October 2024

IntroductionThe response to medical management of young dogs with osteoarthritis (OA) associated pain has not been evaluated. Using an open-label design, the effectiveness, over a 4-month period, of standardized management (grapiprant/fish oil/exercise) for treating OA pain in young dogs was evaluated.MethodsIncluded dogs were 9 months-4 years of age; ≥3.6 kg body weight; had ≥1 appendicular joint with radiographic OA and obvious joint pain; had a Liverpool Osteoarthritis in Dogs (LOAD) score of ≥5. The non-steroidal anti-inflammatory piprant (grapiprant) was given at the recommended dose daily, omega-3 fatty acid supplementation was initiated at 100 mg/kg and then increased to 200 mg/kg daily, and leash exercise was gradually increased to a target of 60 min daily. Client-reported outcome measures (CROMs) and force plate gait analysis were collected at baseline and monthly for 4 months. The index limb was defined as the most severely affected limb at baseline.ResultsForty-eight dogs were enrolled (mean ± SD age of 30.7 ± 10.7 months). Hips, elbows, and stifles were commonly affected. Medication and supplement compliance was excellent (≥95% of target administered), and treatments were well-tolerated. CROMs showed significant improvement over time and at each time point. Overall, peak vertical force (PVF) increased significantly (&lt;0.001), and vertical impulse increased numerically. Increase in PVF from baseline was significant at all time points except 4-months.DiscussionThis study demonstrates a clinically meaningful benefit of a multimodal treatment regimen over a 4-month period for young dogs (&lt;4 years old) with OA-pain. Future work should determine if early, effective treatment is of long-term benefit.
Mitochondrial Genome Assembly and Structural Characteristics Analysis of Gentiana rigescens
Authors: Xie Zongyi , Zhang Yingmin , Wu Lixin , Li Guodong 
Published: October 2024

Gentiana rigescens, an alpine plant with significant medicinal value, possesses a complex genetic background. However, comprehensive genomic research on G. rigescens is still lacking, particularly concerning its organelle genome. In this study, G. rigescens was studied to sequence the mitochondrial genome (mitogenome) and ascertain the assembly, informational content, and developmental expression of the mitogenome. The mitogenome of G. rigescens was 393,595 bp in length and comprised four circular chromosomes ranging in size from 6646 bp to 362,358 bp. The GC content was 43.73%. The mitogenome featured 30 distinct protein-coding genes, 26 tRNA genes, and 3 rRNA genes. The mitogenome of G. rigescens also revealed 70 SSRs, which were mostly tetra-nucleotides. In addition, 48 homologous fragments were found between the mitogenome and the chloroplast genome, with the longest measuring 23,330 bp. The documentation of the mitochondrial genome of G. rigescens is instrumental in advancing the understanding of its physiological development. Decoding the G. rigescens mitogenome will offer valuable genetic material for phylogenetic research on Gentianaceae and enhance the use of species germplasm resources.
MAPAS MENTAIS COMO FERRAMENTA DE ENSINO, APRENDIZAGEM, AVALIAÇÃO E AUTOAVALIAÇÃO EM MATEMÁTICA NOS ANOS FINAIS DO ENSINO FUNDAMENTAL
Authors: Peixoto Nascimemto Samara , De Oliveira Dias Marcelo 
Published: October 2024

O artigo apresenta resultados do mapeamento de pesquisas e de uma intervenção pedagógica que aborda a adoção de mapas mentais como ferramenta de ensino de matemática. A revisão sistemática foi adotada como viés metodológico a fim de apurar como ocorre a utilização dessa ferramenta no ensino de matemática no âmbito de pesquisas acadêmicas e, em seguida, uma proposta de intervenção pedagógica. Os resultados elucidaram lacunas para a abordagem de mapas mentais no ensino de matemática no Ensino Fundamental; escassez de pesquisas referentes a adoção de mapas mentais ligados à disciplina matemática e tendências de adoção de pesquisas de cunho qualitativo. No intuito de superar essa escassez, foi proposta posteriormente uma intervenção por meio de um curso de extensão para docentes com applets desenvolvidos no GeoGebra para a abordagem de habilidades da unidade temática geometria e ao final do curso foi solicitado a construção de mapa mental, a fim de analisar as percepções dos docentes participantes. Desse modo foi possível evidenciar que a implementação da ferramenta dos Mapas Mentais permitiu a análise visual das reflexões desenvolvidas no processo de manipulação das atividades propostas, configurando-se como uma ferramenta significativa para o processo de avaliação e autoavaliação em matemática.
Palavras-chave: Revisão Sistemática, Intervenção Pedagógica, Mapa Mental, Anos Finais do Ensino Fundamental, Geometria.
Human-AI Collaboration: A Student-Centered Perspective of Generative AI Use in Higher Education
Authors: Razmerita Liana 
Published: October 2024

The increasing adoption of generative AI (Gen AI) has made it even more important to investigate how education and learning is transformed. The paper investigates the evolving relationship between humans and AI in performing learning and knowledge-intensive tasks. Based on mixed data collected from business school students, the article explores the evolving relationships between human and AI in knowledge collaboration. The article sets out to address how Gen AI usage affects students’ behavior, their academic work and their attitudes towards AI. It investigates how students use Gen AI in an academic context to support students’ work processes. Our analysis draws on collaborative learning theories and revisits the automation-augmentation paradox in the context of management education. The aim is to address the following research questions: How does collaboration with AI affect student academic work? And how do students in higher education use Gen AI for academic work? We present insights into students’ perception of benefits and drawbacks of using Gen AI, their attitude towards Gen AI, knowledge tasks in which they collaborate or delegate to Gen AI and we discuss the potential risks associated with the use of Gen AI. Students are collaborating with AI using ChatGPT for expanding knowledge on academic themes, summarizing concepts, theories, and generating ideas for research topics and methods. Time saving, enhanced productivity and user-friendliness of the tool were identified as the main benefits associated with Gen AI, whereas the risk of plagiarism, its inaccuracy in responses and the need for prior knowledge were identified as the main drawbacks. While our findings underscore the potential of Gen AI to significantly enhance student learning experiences, they also underscore the importance of exercising caution and awareness of associated risks to automate learning. This study seeks to enrich our comprehension of AI's transformative role in higher education, with a specific focus on the student-centered perspective.
Role of AI-Driven Personalized E-Learning In Enhancing Economic Competitiveness: A Comparative Analysis of Developed And Developing Countries
Authors: Ahmed Sabahat , Meraj Muhammad 
Published: October 2024

This study explores the influence of AI-driven personalized e-learning on the Global Competitiveness Index (GCI) across six countries, comprising three developed (USA, Germany, Japan) and three developing (Pakistan, India and Nigeria) nations, over a span of 17 years (2007-2023). Utilizing a least squares regression model, the analysis incorporates key variables including the Artificial Intelligence Global Index (AIGI), Human Development Index (HDI), and R&D expenditure as control variables to assess their impact on GCI. The model demonstrates a robust fit, with an R2 value of 96.79% and an adjusted R2 value of 96.50%, indicating that AI-enhanced e-learning is a significant predictor as independent variables of economic competitiveness GCI. The findings underscore the significant role of investment in AI and e-learning technologies, particularly in enhancing economic competitiveness, as evidenced by strong positive correlations between GCI and AIGI, HDI, and R&D expenditure. The results are consistent with IBM's research, which highlights the importance of these variables in driving national competitiveness in the global market. The study concludes that AI-driven personalized e-learning is a critical lever for improving GCI, particularly for developing countries aiming to close the competitiveness gap with developed nations. The implications of this research suggest that targeted investments in AI and e-learning can substantially contribute to sustainable economic growth and international competitiveness. This study offers valuable insights for policymakers and educational institutions aiming to enhance their nation's competitiveness through strategic investments in AI-driven educational technologies.
VIRAL TIC-BASED ENCEPHALITIS IN A PREGNANT WOMAN. CLINICAL CASE.
Authors: N.V. Kleban , D.S. Rakhmetova , T.N. Shcherbina , A.N. Baltabekova 
Published: October 2024

The course of acute infections, preeclampsia with symptoms of damage to the central or peripheral nervous system - require to be alert for infectious diseases. In doubtful cases, it is necessary to conduct a bacteriological, virological, serological study of the biomaterial, if necessary, an analysis of the cerebrospinal fluid. A timely correct clinical diagnosis based on a multidisciplinary approach to patient management has a significant impact on a positive outcome of the disease and perinatal outcome. The article presents a case of tick-borne encephalitis, polyradiculoneuritis form, acute course. Shown on a specific example, the difficulty of diagnosing this disease. The information presented in the article is useful for: obstetrician-gynecologists, neonatologists, general practitioners, infectiologists.
Течение острых инфекций, преэклампсии с симптомами поражения центральной или периферический нервной системы – требуют быть настороженным в отношении инфекционных заболеваний. В сомнительных случаях необходимо проводить бактериологическое, вирусологическое, серологическое исследование биоматериала, при необходимости анализ спинномозговой жидкости. Своевременно поставленный правильный клинический диагноз, основанный на мультидисциплинарном подходе к тактике ведения пациентки, существенно влияет на положительный исход заболевания и перинатальный исход. В статье представлен случай клещевого энцефалита у беременной женщины, полирадикулоневритическая форма, острое течение. Показана, на конкретном примере, трудность диагностики данного заболевания. Информация, представленная в статье полезна для: акушер-гинекологов, неонатологов, врачей общей практики, инфекционостов.
Жеделағымдыинфекциялар, орталық немесе перифериялық жүйке жүйесінің зақымдануымен жүретінпреэклампсия-жұқпалыаурулардан сақ болуды талап етеді. Күмәнді жағдайларда биоматериалды бактериологиялық, вирусологиялық, серологиялық зерттеу, қажет болған жағдайдами-жұлынсұйықтығын талдау қажет. Пациентті басқару тактикасына көпсалалы тәсілге негізделген уақтылыдұрыс клиникалық диагноз койылуы аурудың оң нәтижесіне және перинаталдық нәтижеге айтарлықтай әсер етеді. Мақаладажедел ағымды кене энцефалиті, полирадикулоневритикалық түрітуралы жағдай келтірілген. Бұл ауруды диагностикалаудың қиындығы нақты мысалда көрсетілген. Мақалада келтірілген ақпарат пайдалы: акушер-гинекологтарға, неонатологтарға, жалпы тәжірибе дәрігерлерге, инфекционистерге.
Пути развития медицинской микологии в России (Х–XIX вв.): истоки, становление, первые шаги
Authors: Д.В. Заславский , Л.В. Белова 
Published: October 2024

Цель. Проанализировать малоизученные вопросы путей развития медицинской микологии в России (Х–XIX вв.). Материалы и методы. Изучение лечебников, травников, сборников, трактатов и трудов ценителей русской народной медицины, научных трудов и докладов, изданий периодической печати, воспоминаний современников. Представлены редкие фотографии. Обсуждение. Восполнен пробел в историко-медицинской литературе. Дано целостное представление о развитии отечественной медицинской микологии (Х–XIX вв.). Показаны истоки отечественной медицинской микологии в русской народной медицине, ее становление и выделение из общей микологии, первые шаги, полемика ученых, их точки зрения, мнения, предложения, доводы. Проанализированы научные труды, определены приоритеты российских ученых, их вклад в мировую науку. Заключение. Зарождение и становление медицинской микологии в России происходило своими, самобытными путями. Бесценный опыт российских ученых и врачей в изучении медицинской микологии является достоянием отечественной медицины, непреходящей ценностью для следующих поколений.
The purpose. To analyze the poorly studied issues of the development of medical mycology in Russia (10th–19th centuries). Materials and methods. Study of medical books, herbalists, collections, treatises and works of connoisseurs of Russian folk medicine, scientific works and reports, periodicals, memoirs of contemporaries. Rare photographs are presented. Discussion. The gap in the historical and medical literature is filled. A holistic view of the development of domestic medical mycology is given (10th–19th centuries). The article shows the origins of domestic medical mycology in Russian folk medicine, its formation and separation from general mycology, the first steps, the controversy of scientists, their points of view, opinions, proposals, and arguments. Scientific works are analyzed, the priorities of Russian scientists and their contribution to world science are determined. Conclusion. The origin and formation of medical mycology in Russia occurred in its own, original ways. The invaluable experience of Russian scientists and doctors in the study of medical mycology is the property of domestic medicine, an enduring value for future generations.
EV Mobility for Cyber Security and Safety through Communication Protocol
Authors: Uthaman Sreekumar , Dr. Urmila Patil  
Published: October 2024

Government of India have initiated various schemes like FAME for the rapid increase in the electrification of road transportation due to various reasons such as escalating pollution, global warming, etc. This has led to the development and installation of charging infrastructure throughout the country. DC Fast charging systems have been in place for charging EV at a faster rate. EV and EVSE are manufactured based on various DC Fast Charging communication protocols, viz. DC001, CHAdeMO, CCS, and GB/T.
Testing EV charging stations is essential in three main areas: development, installation, and maintenance. Manufacturers of EVs and chargers must guarantee compatibility and dependability at every level. It is crucial that EVs and charging stations operate together securely and without hiccups. Extensive testing can guarantee driver safety and prevent damage to automobiles. The paper goes through the various safety measures needed to be incorporated in the cyber security safety of EVs and EV chargers.
Keywords: EV Mobility, cyber security, communication protocols, EV Charger, BMS, Cyber-attacks, EVSE, EV emulator
Thermal Management of Avionic Packages
Authors: K. Velmurugan  , M. Prabu  , S. Ramanathan  , Jawad Abdul Jaleel Mohammad  , J.V. Shanmukha Sriram  , Nitinchaitanya Prahasith Maddury  , Mohd. Abdul Mukheet  
Published: October 2024

The study uses computer-aided design (CAD) software to design and fabricate printed circuit boards (PCBs). The primary goal is to conduct a thermal study with the goal to determine its suitability for use in avionic applications. A Brushless DC (BLDC) motor is connected to the PCB via 24 Metal Oxide Semiconductor Field Effect Transistors (MOSFETs) which are connected to it by a Pulse Width Modulation Signal (PWMS). Given the potential effect of these MOSFETs' failure on the functionality of the PCB, maintaining their reliability becomes more crucial as external temperatures rise.
The PCB is tested at ambient (28°C) conditions with isolated load, no load, and maximum load settings. Following that, simulated outcomes with Siemens Simcenter FlothermXT are compared with the experimental findings. An in-depth understanding of MOSFET thermal behaviour, including changes in temperature at the component and board levels, is made possible through this comparative analysis. The aim of this iterative approach is to maintain the PCB's safe operation within the set temperature limits.
Keywords: Avionic Package, MOSFET, PCB, Thermal Analysis, Spring Load, Load Condition
Fully Kinetic Simulations of Proton-beam-driven Instabilities from Parker Solar Probe Observations
Authors: Pezzini L. , Zhukov A. N. , Bacchini F. , Arrò G. , López R. A. , Micera A. , Innocenti M. E. , Lapenta G. 
Published: October 2024

Abstract
The expanding solar wind plasma ubiquitously exhibits anisotropic nonthermal particle velocity distributions. Typically, proton velocity distribution functions (VDFs) show the presence of a core and a field-aligned beam. Novel observations made by the Parker Solar Probe (PSP) in the innermost heliosphere have revealed new complex features in the proton VDFs, namely anisotropic beams that sometimes experience perpendicular diffusion. In this study, we use a 2.5D fully kinetic simulation to investigate the stability of proton VDFs with anisotropic beams observed by PSP. Our setup consists of a core and an anisotropic beam population that drift with respect to each other. This configuration triggers a proton beam instability from which nearly parallel fast magnetosonic modes develop. Our results demonstrate that before this instability reaches saturation, the waves resonantly interact with the beam protons, causing perpendicular heating at the expense of the parallel temperature.
Merging Signatures in an Offset Lyman Continuum Emitter at Redshift 3.8
Authors: Yuan Fang-Ting , Zheng Zhen-Ya , Jiang Chunyan , Zhu Shuairu , Lin Ruqiu , Cheng Cheng 
Published: October 2024

Abstract
Lyman continuum (LyC) emitters at z > 3 provide critical samples for studying the contribution of galaxies to the ionizing background in the epoch of reionization. We collect a sample of z > 3 LyC emitters, a dominant fraction (∼60%–70%) of which show spatial offsets between LyC emission and the nonionizing continuum. From this sample, especially, we find a case of an offset LyC emitter, CDFS-6664 (z = 3.797), which shows two components in the high-resolution Hubble Space Telescope and James Webb Space Telescope images. The exceptionally rich data set of CDFS-6664 enables us to extract the two components across multiple wavelengths and estimate their physical properties. We show that CDFS-6664 is consistent with a major merger system with boosted star formation in both components and that the offset LyC emission is most likely associated with the bluer and younger component in this merging system. Our result offers an example in which the offset can be caused by a merger. Future observations of more offset LyC emitters would elucidate the role that mergers play in the escape of LyC photons.