bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing native parasitoids of the invasive pest Drosophila suzukii (Diptera: Drosophilidae) in the Southeastern USA
Authors: Neupane Subin B , Schmidt Jason M , Snyder William E , Hudson William G , Wang Xingeng , Buffington Matthew , Daane Kent M , Sial Ashfaq A 
Published: October 2024

Abstract
Drosophila suzukii (Matsumura) (Diptera: Drosophilidae), commonly known as spotted-wing Drosophila (SWD), is an invasive insect pest threatening the economy of many small fruit farms in the Americas and Europe. Biological control using parasitoids is a promising strategy for improving the sustainable management of SWD. To use the parasitoids as biocontrol agents, recognizing and understanding the presence and preference of North American native parasitoids and their local adaptation is necessary. We conducted 2 season-long field explorations of North American native parasitoids of SWD during 2021 and 2022 at major blueberry-producing locations in southeast GA, USA. A total of 371 parasitoids of Drosophila were collected using fruit-baited sentinel traps and classified into 3 families: Figitidae, Pteromalidae, and Diapriidae. Leptopilina boulardi (Hymenoptera: Figitidae) and Pachycrepoideus vindemmiae (Hymenoptera: Pteromalidae) were the most abundant species. The abundance of parasitoids was higher during the peak blueberry ripening period through the end of the harvest season compared to all other phenological stages. Out of the North American native parasitoids of SWD that we collected, Pachycrepoideus vindemmiae successfully parasitized SWD in its natural habitat, and L. boulardi only parasitized SWD larvae at a low rate of 7% in the laboratory, but it failed to emerge from all the parasitized SWD. Ultimately, we found that the existing North American native parasitoids were inadequate to suppress the SWD in these locations. Planned intervention with the classical release of Asian native specialist parasitoids in addition to the existing SWD management approaches was deemed necessary in these areas.
Spontaneous thrombosis of an unroofed coronary sinus: case report
Authors: Gupta Krishna , Kasargod Prabhakar Chethan Ram , Kueh Shaw Hua 
Published: October 2024

Abstract

Background
Unroofed coronary sinus (UCS) is a rare congenital anomaly and is usually found incidentally. While coronary sinus thrombosis (CST) can occur following instrumentation of the coronary sinus, spontaneous CST is a rare occurrence and only a few cases have been reported to date. The presence of both rare entities concurrently has not been reported previously.

Case summary
A 57-year-old man presented with rectal bleeding and was in hypovolaemic shock. On computed tomography (CT), he was found to have ischaemic colitis as well as an incidental finding of a Type IV UCS with CST. He was initially managed with intravenous heparin infusion but developed life-threatening upper gastrointestinal bleeding, requiring endoscopic clipping of a gastric ulcer. The patient was recommenced on intravenous heparin and later transitioned to oral anticoagulant without further events.

Discussion
In UCS, the coronary sinus communicates with the left atrium. The majority of patients are asymptomatic, and the anomaly usually goes undetected. In this patient, UCS was found incidentally with concurrent spontaneous CST. The ischaemic colitis was likely due to cardioembolism from the CST. In the absence of evidence-based practice, we described our cautious approach to anticoagulation in this critically unwell patient. Furthermore, advances in cardiac intervention have seen an increasing need to instrument the coronary sinus and an increased awareness of coronary sinus anomalies is important. Cardiac CT provides an excellent imaging tool for assessing the coronary sinus anatomy (as demonstrated in this case) and can be helpful in pre-procedural planning.
The impact of large aneurysm diameter on the outcomes of thoracoabdominal aneurysm repair by fenestrated and branched endografts
Authors: Gallitto Enrico , Tsilimparis Nikolaos , Spath Paolo , Faggioli Gianluca , Stana Jan , Logiacco Antonino , Fernandez-Prendes Carlota , Pini Rodolfo , Rantner Barbara , Mascoli Chiara , Cappiello Antonio , Gargiulo Mauro 
Published: October 2024

AbstractOBJECTIVESAim of the study was to analyse the impact of preoperative thoracoabdominal aneurysm diameter on the outcomes of fenestrated/branched endografting.METHODSPatients who underwent endovascular thoracoabdominal repair at 2 European centres (2011–2021) were analysed. Median diameter was calculated; the third quartile was considered a cut-off. Outcomes were compared in 2 groups based on the diameter value. Primary endpoints were technical success, spinal cord ischaemia and 30-day/in-hospital mortality. Survival, freedom from reintervention and target visceral vessels instability were follow-up outcomes.RESULTSOut of 247 thoracoabdominal aortic aneurysms, the median diameter was 65 mm, first quartile was 57 mm; third quartile was 80 mm, set as cut-off value. Fifty-nine (24%) patients had diameter ≥80 mm. Custom-made and off-the-shelf branched endograft were used in 160 (65%) and 87 (35%), respectively. Technical success was 93% (&lt;80 mm: 91% vs ≥80 mm: 94%; P = 0.47). Twenty-three (9%) patients had spinal injury (&lt;80 mm: 7% vs ≥80mm: 17%; P = 0.03). Twenty-two (9%) patients died within 30-day/in-hospital (&lt;80 mm: 7% vs ≥80 mm: 15%; P = 0.06). Multivariate analysis did not report preoperative diameter ≥80 mm as significant risk factor for primary endpoints. The median follow-up was 13 (interquartile range: 2–37) months and at 3-year survival and freedom from reintervention rates were 65% and 62%, respectively. After univariate and multivariate analyses, preoperative diameter ≥80 mm was considered an independent risk factor for reinterventions [hazard ratio (HR): 1.9; 95% confidence interval (CI) 1.1–3.6; P = 0.04], and for target visceral vessels instability (HR: 3.1; 95% CI: 1.3–5.1; P = 0.04), occurred in 45 (18%) cases. However, after competing risk methods, preoperative diameter did not show significance for follow-up results.CONCLUSIONSA preoperative thoracoabdominal aortic aneurysm diameter &gt;80 mm has not had a direct impact on early technical and clinical outcomes. A diameter≥80 mm is considered risk factor for reinterventions and target vessels instability is considered separately during follow-up.
European multicentre study evaluating the prognosis of peripheral early-stage lung adenocarcinoma patients operated on by segmentectomy or lobectomy
Authors: Lula Lukadi Joseph , Costa Rita , Rushwan Amr , Barreda Clara Forcada , Domjan Matic , Marinucci Beatrice Trabalza , Jasovic Crt , Özgür Emrah Gökay , Savu Cornel , Rendina Erino Angelo , Bekiroglu Nural , Fernandes Pedro , Jimenez Marcelo , Stupnik Tomaz , D’Andrilli Antonio , Martinod Emmanuel , Brunelli Alessandro 
Published: October 2024

Abstract

OBJECTIVES
To analyse impact of segmentectomy on oncological outcomes of different peripheral early-stage lung adenocarcinoma patterns.

METHODS
Retrospective multicentre study including patients who underwent either lobectomy or segmentectomy in 6 European centres from 2015 to 2021, for ≤2 cm pathological peripheral lung adenocarcinoma. Overall and disease-free survivals were assessed by cox-regression and lung cancer-specific survival by competing regression analyses to adjust for patient- and tumour-related factors both in the entire dataset and the in aggressive adenocarcinoma patterns dataset.

RESULTS
Lobectomy and segmentectomy were performed in 481 (71%) and 193 (29%) patients, respectively. Propensity score matching was performed (n = 191). One hundred and 8 patients had a least an aggressive pattern. Five-year disease-free, overall and lung cancer-specific survivals were similar between patients who underwent lobectomy or segmentectomy in both entire and aggressive pattern datasets. In patients with aggressive pattern, 5-year disease-free (lobectomy 87.3%; segmentectomy 86.6%, P = 0.62), overall (lobectomy 86.4%; segmentectomy 95.6%, P = 0.61) and lung cancer-specific (lobectomy 100%; segmentectomy 95.6%, P = 0.13) survivals did not differ. Segmentectomy was not an independent risk factor for disease-free survival, neither for overall survival nor for lung cancer-specific survival in any of the 2 datasets. In patients with aggressive pattern, loco-regional recurrence (linearized risks: lobectomy 8.21; segmentectomy 11.3) was higher in patients who underwent segmentectomy.

CONCLUSIONS
Resection should not be extended (to lobectomy) on patients who underwent segmentectomy for pathologically proven early-stage adenocarcinoma with aggressive patterns.
Differential responses of woodland caribou to fire and forestry across boreal and montane ecosystems—a literature review
Authors: Stevenson Suzanne , Finnegan Laura , Johnson Chris , McKay Tracy 
Published: October 2024

Abstract
Ecosystem-based management (EBM) is a landscape-level management and planning process that is common across North America. A primary tenet of EBM is that the area and intensity of anthropogenic disturbance should mimic the historical natural disturbance of the focal ecosystem. Biodiversity should persist, at least at a coarse scale, where anthropogenic disturbance, such as forest harvesting, matches natural disturbance. However, EBM is failing some species, particularly those that are dependent on old forest. Across many areas of Canada, woodland caribou (Rangifer tarandus caribou) are declining because of the direct and indirect effects of habitat loss and fragmentation. This is even though forest management often follows the principles of EBM. We conducted a qualitative comparison of the responses of woodland caribou to wildfire and forest harvesting, considering a broad range of responses, including habitat selection and distribution, forage, movement patterns, and population dynamics. We found that while wildfire and forest harvesting both influence caribou, the negative effects are generally greater following forest harvesting. For example, wildfire and forest harvesting result in the loss of habitat, but caribou are more likely to shift, abandon or contract their range in response to harvest. The literature also suggested a stronger negative population response of caribou to forest harvest when compared to wildfire. This difference could be the result of greater residual forest structure associated with wildfire as well as the extensive resource roads that are necessary for forestry operations. Although there is sound theoretical support for EBM, the practice, as implemented, may not be effective for maintaining the habitat and ultimately populations of woodland caribou.
I want to climb to the tops of trees! Factors facilitating the development of ivy vines in central European forests
Authors: Wyka Jakub , Dyderski Marcin K , Grzędzicka Emilia , Lešo Peter , Piechnik Łukasz , Kajtoch Łukasz 
Published: October 2024

Abstract
Lianas, which are considered to form tree-related microhabitats, are known as important elements of tropical forests; however, their ecological function and relationships with host trees (phorophytes) in temperate forests are poorly known. This gap in knowledge stems from a low species diversity and abundance of lianas in temperate forests. An exception is common ivy (Hedera helix), which is widely distributed and is currently increasing its abundance in temperate forests. In this study, we examined the relationships between ivy vines with features of their phorophytes, using Central European upland mixed forests as an example. We assess the presence and density of ivy within 69 study plots, established in the forest interior and ecotone. We use generalized linear mixed-effects models to assess drivers of ivy’s presence and its density, while accounting for the tree diameter at breast height, bark roughness, and the canopy light transmittance. We show that ivy is able to grow on nearly all tree species, although it prefers phorophytes with rough bark and a large diameter. Large generative individuals (ivy vines that produce fruits) were found mostly on veteran trees (usually oaks, alders, or pines). For its growth, ivy requires tree phorophytes with only a moderate transparency of light through the tree crowns, which is likely related to evergreen leaves that enable ivy vines to also develop during leaf-off periods. The features of phorophytes preferred by ivy indicate that the vine finds optimal conditions for development in old patches of tree stand, often in areas inaccessible or unprofitable for forest management. We propose using large and fruiting ivy vines as indicators of old-growth forests that deserve protection, which would be in line with the current policy of sustaining and restoring close-to-natural forests in Europe.
Higher-order epistasis within Pol II trigger loop haplotypes
Authors: Duan Bingbing , Qiu Chenxi , Lockless Steve W , Sze Sing-Hoi , Kaplan Craig D 
Published: October 2024

Abstract
RNA polymerase II (Pol II) has a highly conserved domain, the trigger loop (TL), that controls transcription fidelity and speed. We previously probed pairwise genetic interactions between residues within and surrounding the TL for the purpose of understanding functional interactions between residues and to understand how individual mutants might alter TL function. We identified widespread incompatibility between TLs of different species when placed in the Saccharomyces cerevisiae Pol II context, indicating species-specific interactions between otherwise highly conserved TLs and their surroundings. These interactions represent epistasis between TL residues and the rest of Pol II. We sought to understand why certain TL sequences are incompatible with S. cerevisiae Pol II and to dissect the nature of genetic interactions within multiply substituted TLs as a window on higher-order epistasis in this system. We identified both positive and negative higher-order residue interactions within example TL haplotypes. Intricate higher-order epistasis formed by TL residues was sometimes only apparent from analysis of intermediate genotypes, emphasizing complexity of epistatic interactions. Furthermore, we distinguished TL substitutions with distinct classes of epistatic patterns, suggesting specific TL residues that potentially influence TL evolution. Our examples of complex residue interactions suggest possible pathways for epistasis to facilitate Pol II evolution.
Longitudinal Changes in Peak Expiratory Flow Predict Risk for Incident Dementia
Authors: Donahue Patrick T , Balasubramanian Aparna , Xue Qian-Li , Schrack Jennifer A , Carlson Michelle C 
Published: October 2024

Abstract

Background
Impaired respiratory function, measured via peak expiratory flow (PEF), has been associated with increased dementia risk. However, much of the current literature uses cross-sectional measures of PEF, whereas longitudinal relationships between changes in respiratory function and dementia risk are underexplored.

Methods
Using 10 years of data (2011–2021) from 2 439 adults ages 65 and older in the National Health and Aging Trends Study, we examined whether 5-year changes in PEF (2011–2016) were associated with risk for incident dementia over the subsequent 5-year period (2017–2021). PEF slopes for each participant were estimated using linear mixed-effects models and then grouped into quartiles: rapid, moderate, mild, and no declines. Discrete-time Cox proportional hazards models were used to estimate the risk for incident dementia by PEF slope category while controlling for several health and sociodemographic characteristics.

Results
After excluding dementia cases during the exposure window (2011–2016), we identified 338 cases of incident dementia (13.9%) between 2017–2021. Rapid PEF declines between 2011–2016 were associated with 85% higher risk for incident dementia between 2017–2021 compared to those with no declines in PEF (hazard ratio = 1.85; 95% confidence interval [1.24, 2.76]). Results were robust to several sensitivity analyses.

Conclusions
These findings demonstrate that declines in PEF may precede declines in cognition, suggesting that respiratory function may be an important dementia risk factor in older adults. Additionally, these findings highlight the utility of measuring PEF via a peak flow meter, which is a simple and inexpensive measure of respiratory function.
Delineating Care Recipient Burden Constructs: Development and Validation of the CARE-2B Scale for Care Recipient Self-Perceived Burden and Proxy Assessment of Caregiver Burden
Authors: Kuharic Maja , Mulhern Brendan , Sharp Lisa K , Turpin Robin S , Pickard A Simon 
Published: October 2024

Abstract

Background and Objectives
Care Recipient Self-Perceived Burden (CR-SPB) to Caregivers is an important but overlooked aspect within the caregiver-care recipient relationship. This study aimed to 1) develop and validate the CARE-2B (Care Recipient's Two Burden) Scale, assessing both CR-SPB and their proxy assessment of caregiver burden (Proxy-CB); 2) examine whether the CR-SPB and Proxy-CB differ from caregiver burden’s own assessment and other health and social care constructs.

Research Design and Methods
Data were collected from 504 caregiver-care recipient dyads in the US using an online panel between August 2022 and February 2023. Care recipients completed the CARE-2B Scale, which includes two subscales: their self-perceived burden (CR-SPB) and their proxy assessment of caregiver burden (Proxy-CB). Care recipients also completed measures related to health, well-being: SPB-scale, EQ-5D-5L, and EQ-HWB. Caregivers completed CarerQoL and ASCOT-Carer. Psychometric analysis included exploratory and confirmatory factor analysis, item response theory (IRT), and construct validity.

Results
CR-SPB correlated strongly with the SPB-Scale (r=0.73), while Proxy-CB correlated more strongly with caregiver-reported burden (r=0.61). Both CR-SPB and Proxy-CB items demonstrated good discrimination and information coverage in IRT analysis. EFA further supported the distinctiveness of CR-SPB and Proxy-CB, with CR-SPB items loading on a separate factor from caregiver burden and health constructs, while Proxy-CB aligned with caregiver-reported burden.

Discussion and Implications
The CARE-2B Scale innovatively assesses both CR-SPB and Proxy-CB from the care recipient's perspective, providing new insights into the caregiving relationship. This dual-perspective measure has implications for enhancing care strategies for individuals with chronic conditions or disabilities and their caregivers.
A real scale application of a novel set of spatial and similarity features for detection and classification of natural seismic sources from distributed acoustic sensing data
Authors: Huynh C , Hibert C , Jestin C , Malet J -P , Lanticq V 
Published: October 2024

SUMMARY
Distributed acoustic sensing (DAS) turns a fibre optic into a very dense network of equally distributed seismic sensors. We focused on the high-density sampling of the seismic wavefield, expressed in strain rates, measured by DAS. Classical approaches used to identify seismic signals rely on the recorded features at one station, but it is difficult to include spatial information in case of dense seismic station networks. This work aims at introducing new spatial and similarity features for seismic event classification suitable to analyse DAS observations. We propose a processing chain based on the XGBoost algorithm and the use of specifically designed spatiotemporal and similarity features for the event classification, and Markov random field for the spatial clustering. The methodology is designated to be applied on a continuous stream of DAS observations. We tested our processing chain to detect earthquakes and quarry blasts recorded in the region by permanent seismic networks and included in the RENASS catalogue. These events are part of a strain-rate seismic survey carried out during a 3 weeks campaign of DAS measurements along à 91 km fibre optic cable deployed in the central Pyrenees mountains (France). Despite the high anthropogenic activities along the fibre optic path, the proposed method succeeded in detecting earthquakes of magnitude &gt;0.4 and quarry blasts of magnitude &gt;1.0 while limiting the number of false alarms. This performance is particularly noteworthy for low-magnitude events, where detection is accomplished despite a lower signal-to-noise ratio compared to traditional seismometers. The methodology opens the door to real time detection and classification of seismic events measured with long-distance fibre optic systems.
Suitability of smoking cessation support from social and community service organizations: perspectives of Dutch clients
Authors: Visser Judith E M , Burger Judith , Rozema Andrea D , Kunst Anton E , Kuipers Mirte A G 
Published: October 2024

Abstract
Social and community service organizations (SCSOs) may be a promising new environment to more successfully reach people with a lower socioeconomic position (SEP) for smoking cessation support. However, studies that investigate clients’ perspectives of the suitability of SCSOs as a setting to discuss smoking are scarce. This study aimed to (i) investigate the suitability of smoking cessation support provided by SCSOs, according to people with a low SEP, and (ii) explore their reasons for considering it suitable or unsuitable. Semi-structured interviews were conducted with 19 individuals with a low SEP who smoked regularly (N = 14) or had smoked regularly (N = 5). They have been in contact with SCSOs in a specific neighborhood in Amsterdam. Data were analyzed using a thematic approach. Participants generally considered SCSOs as suitable for providing smoking cessation support, as professionals are involved, build a relationship of trust, and offer personalized and holistic support. SCSOs are located nearby and familiar, they provide support in both group and individual settings and might offer additional supportive (group)activities. A number of participants expressed doubts about the waiting time for support, the fact that the needed support might exceed professionals’ expertise, and the lack of aftercare. SCSOs can be an additional opportunity for providing smoking cessation support that aligns with the circumstances of lower SEP people. To harness the potential, smoking cessation could be integrated into education programs and training among professionals could be promoted. Policy changes within and outside SCSOs would be needed.
The Genocide Convention is “Our Cause”: International Women’s Advocacy for the Criminalization of Genocide, 1945–1952
Authors: Kimble Sara L 
Published: October 2024

Abstract
In 1948, the United Nations Convention on the Prevention and Punishment of the Crime of Genocide was official recognized under international law. Few, however, understand the role of international women’s rights organizations in the politics of the convention, the ratification process, and its application in the immediate postwar era. Rooted in their knowledge of Nazi atrocities and wartime activism, women’s organizations supported Raphael Lemkin’s campaign, but also critiqued the convention’s failure to address sexual violence and political repression of certain vulnerable groups. This article explores how women’s rights leaders supported the Genocide Convention as a crucial mechanism for preventing a repetition of atrocities, how they committed early on to applying the law to intervene and protect human rights, and how fissures later emerged between these various international women’s rights groups in the Cold War era.