bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infrared reflectance spectroscopy of MgAl2O4 nanoparticles substituted by K+ ions
Authors: Ahmad Javed , Qadeer Awan M. , Yasmin Roomana , Sabir Maria , Anwar Shafiq , Ehsan Mazhar M. , Hamad Bukhari Syed 
Published: November 2017

The infrared reflectivity spectra for potassium-doped polycrystalline magnesium aluminates Mg[Formula: see text]K[Formula: see text]Al2O4 (x=0, 0.25, 0.50, 0.75, 1) are measured in the frequency range between 10–15, 500 cm[Formula: see text] using FTIR spectrometer at room-temperature. Four optical phonon modes are observed in measured spectra, which are fitted by Lorentz oscillator model for semiconducting behavior and Lorentz–Drude model for metallic behavior. Moreover, optical parameters are also determined for these modes which may attribute to spinel structure for samples Mg[Formula: see text]K[Formula: see text]Al2O4, their reflectivity spectra shows a typical semiconducting nature. To study ionicity and effect of polarization, Born and Szigeti effective charges are calculated from longitudinal optical and transverse optical (LO–TO) splitting of modes for all samples. Optical bandgap has been estimated through optical conductivity ([Formula: see text]([Formula: see text])) and found to be x dependent.
Olaratumab Exerts Antitumor Activity in Preclinical Models of Pediatric Bone and Soft Tissue Tumors through Inhibition of Platelet-Derived Growth Factor Receptor α
Authors: Lowery Caitlin D. , Blosser Wayne , Dowless Michele , Knoche Shelby , Stephens Jennifer , Li Huiling , Surguladze David , Loizos Nick , Luffer-Atlas Debra , Oakley Gerard J. , Guo Qianxu , Iyer Seema , Rubin Brian P. , Stancato Louis 
Published: November 2017

Abstract
Purpose: Platelet-derived growth factor receptor α (PDGFRα) is implicated in several adult and pediatric malignancies, where activated signaling in tumor cells and/or cells within the microenvironment drive tumorigenesis and disease progression. Olaratumab (LY3012207/IMC-3G3) is a human mAb that exclusively binds to PDGFRα and recently received accelerated FDA approval and conditional EMA approval for treatment of advanced adult sarcoma patients in combination with doxorubicin. In this study, we investigated olaratumab in preclinical models of pediatric bone and soft tissue tumors.
Experimental Design: PDGFRα expression was evaluated by qPCR and Western blot analysis. Olaratumab was investigated in in vitro cell proliferation and invasion assays using pediatric osteosarcoma and rhabdoid tumor cell lines. In vivo activity of olaratumab was assessed in preclinical mouse models of pediatric osteosarcoma and malignant rhabdoid tumor.
Results: In vitro olaratumab treatment of osteosarcoma and rhabdoid tumor cell lines reduced proliferation and inhibited invasion driven by individual platelet-derived growth factors (PDGFs) or serum. Furthermore, olaratumab delayed primary tumor growth in mouse models of pediatric osteosarcoma and malignant rhabdoid tumor, and this activity was enhanced by combination with either doxorubicin or cisplatin.
Conclusions: Overall, these data indicate that olaratumab, alone and in combination with standard of care, blocks the growth of some preclinical PDGFRα-expressing pediatric bone and soft tissue tumor models. Clin Cancer Res; 24(4); 847–57. ©2017 AACR.
Value of Excess Pressure Integral for Predicting 15‐Year All‐Cause and Cardiovascular Mortalities in End‐Stage Renal Disease Patients
Authors: Huang Jui‐Tzu , Cheng Hao‐Min , Yu Wen‐Chung , Lin Yao‐Ping , Sung Shih‐Hsien , Wang Jiun‐Jr , Wu Chung‐Li , Chen Chen‐Huan 
Published: November 2017

Background

The excess pressure integral (
XSPI
), derived from analysis of the arterial pressure curve, may be a significant predictor of cardiovascular events in high‐risk patients. We comprehensively investigated the prognostic value of
XSPI
for predicting long‐term mortality in end‐stage renal disease patients undergoing regular hemodialysis.

Methods and Results

A total of 267 uremic patients (50.2% female; mean age 54.2±14.9 years) receiving regular hemodialysis for more than 6 months were enrolled. Cardiovascular parameters were obtained by echocardiography and applanation tonometry. Calibrated carotid arterial pressure waveforms were analyzed according to the wave‐transmission and reservoir‐wave theories. Multivariable Cox proportional hazard models were constructed to account for age, sex, diabetes mellitus, albumin, body mass index, and hemodialysis treatment adequacy. Incremental utility of the parameters to risk stratification was assessed by net reclassification improvement. During a median follow‐up of 15.3 years, 124 deaths (46.4%) incurred. Baseline
XSPI
was significantly predictive of all‐cause (hazard ratio per 1
SD
1.4, 95% confidence interval 1.15‐1.70,
P
=0.0006) and cardiovascular mortalities (1.47, 1.18‐1.84,
P
=0.0006) after accounting for the covariates. The addition of
XSPI
to the base prognostic model significantly improved prediction of both all‐cause mortality (net reclassification improvement=0.1549,
P
=0.0012) and cardiovascular mortality (net reclassification improvement=0.1535,
P
=0.0033).
XSPI
was superior to carotid‐pulse wave velocity, forward and backward wave amplitudes, and left ventricular ejection fraction in consideration of overall independent and incremental prognostics values.

Conclusions

In end‐stage renal disease patients undergoing regular hemodialysis,
XSPI
was significantly predictive of long‐term mortality and demonstrated an incremental value to conventional prognostic factors.
Combined serum free light chain levels are associated with carotid atherosclerosis in type 2 diabetes mellitus
Authors: Aberer Felix , Tripolt Norbert Joachim , Scharnagl Hubert , Zedler Julian , Eder Michaela , Oulhaj Abderrahim , Stojakovic Tatjana , Sourij Harald 
Published: November 2017

Background: Patients with type 2 diabetes mellitus face an increased risk of cardiovascular events compared to non-diabetic counterparts. Chronic inflammation and activation of the immune system, including B-lymphocyte maturation is believed to play a role in atherosclerosis. Recent investigations suggest combined serum free light chains as a potential biomarker for cardiovascular events. The aim of this analysis was to investigate the association of combined serum free light chain with carotid atherosclerosis in subjects with type 2 diabetes mellitus. Methods: We performed a cross-sectional analysis of data from a prospective single centre 2-year study of 97 patients with type 2 diabetes mellitus and insufficiently controlled cardiovascular risk factors. Complete data on combined serum free light chain, high-sensitivity C-reactive protein were available for 75 subjects. Results: We analysed data of 26 female and 49 male subjects, aged 59 ± 8 years. Their mean body mass index was 31.6 ± 4.4 kg/m2, and the median B-score was 2 (interquartile range: 0–3). Significant positive correlations between combined serum free light chain and the B-score ( r = 0.38; p = 0.001) as well as combined serum free light chain and high-sensitivity C-reactive protein ( r = 0.35; p = 0.002) were observed. The adjusted odds ratio for a half standard deviation increase in combined serum free light chain was 1.48 (95% confidence interval: 1.05–2.05) in an ordinal regression model for carotid B-score. Conclusion: In our study, combined serum free light chain was associated with carotid atherosclerosis in subjects with type 2 diabetes mellitus.
The Impact of Time to Rate Control of Junctional Ectopic Tachycardia After Congenital Heart Surgery
Authors: Lim Joel Kian Boon , Mok Yee Hui , Loh Yee Jim , Tan Teng Hong , Lee Jan Hau 
Published: November 2017

Background: Junctional ectopic tachycardia (JET) after congenital heart disease (CHD) surgery is often self-limiting but is associated with increased risk of morbidity and mortality. Contributing factors and impact of time to achieve rate control of JET are poorly described. Methods: From January 2010 to June 2015, a retrospective, single-center cohort study was performed of children who developed JET after CHD surgery . We classified the cohort into two groups: patients who achieved rate control of JET in ≤24 hours and in >24 hours. We examined factors associated with time to rate control and compared clinical outcomes (mortality, duration of mechanical ventilation, length of intensive care unit [ICU], and hospital stay) between the two groups. Results: Our cohort included 27 children, with a median age of 3 (interquartile range: 0.7-38] months. The most common CHD lesions were ventricular septal defect (n = 10, 37%), tetralogy of Fallot (n = 7, 25.9%), and transposition of the great arteries (n = 4, 14.8%). In all, 15 (55.6%) and 12 (44.4%) patients achieved rate control of JET in ≤24 hours and >24 hours, respectively. There was a difference in median mechanical ventilation time (97 [21-145) vs 311 [100-676] hours; P = .013) and ICU stay (5.0 [2.0-8.0] vs 15.5 [5.5-32.8] days, P = .023) between the patients who achieved faster rate control than those who didn’t. There was no difference in length of hospital stay and mortality between the groups. Conclusion: Our study demonstrated that time to achieve rate control of JET was associated with increased duration of mechanical ventilation and ICU stay.
Diagnósticos de Enfermagem Identificados em Pessoas Idosas com Diabetes mellitus
Authors: Lacerda Nivaneide Ferreira Ramos de Sousa , Lima Pollyanna Viana 
Published: November 2017

O objetivo foi Identificar os diagnósticos de enfermagem em pessoas idosas com Diabetes mellitus atendido em uma Estratégia Saúde da Família. Metodologia: Trata-se de um estudo de casos múltiplos, realizado com 20 idosos portadores de Diabetes mellitus, realizado em setembro e outubro de 2017. Para a coleta de dados foi utilizado dois instrumentos: Questionário Sóciobiodemográfico e Econômico e Roteiro para anamnese e exame físico. O projeto obteve aprovação do Comitê de Ética em Pesquisa da Faculdade Independente do Nordeste, com parecer de aprovação nº 2.261.878. Resultados: Foram encontrados 14 diagnósticos diferentes, entre os mais evidenciados, destaca-se: risco de integridade da pele prejudicada (100%); risco de lesão (100%); risco para infecção (100%); dor crônica (100%); síndrome do idoso frágil (60%); risco de trauma (50%), acuidade visual prejudicada (50%) e risco de quedas (50%). Considerações Finais: Foi evidenciado que os idosos apresentam inúmeros problemas relacionados ao diabetes e são extremamente susceptíveis a complicações.
O Autismo e as Dificuldades no Processo de Aprendizagem Escolar
Authors: Ferreira Mônica Misleide Matias , França Aurenia Pereira de 
Published: November 2017

Este artigo aborda sobre a temática do autismo e as dificuldades no processo de aprendizagem escolar, ressaltando o ensino aprendizagem e adaptação a escola. De modo que, desenvolva adequadamente as competências cognitivas e sociais das crianças autista. O artigo em pauta objetivou-se a compreender o processo de aprendizagem da criança autista no ambiente escolar. A metodologia utilizada para desenvolver o presente estudo é de ordem bibliográfica, uma pesquisa qualitativa de autores renomados como: Mantoan (2006), Varella (2011), Wendell (2013), Orrú (2013), Mello (2013) entre outras fontes. Observou-se que é de grande relevância o tema em questão, para que profissionais, familiares e a sociedade compreenda como se dá a aprendizagem de criança portadora de autismo. A criança autista necessita de métodos e acompanhamento especializado.
Pengaruh suplementasi vitamin e (α-tokoferol) terhadap kadar gamma glutamil transferase (ggt) dan kadar nitric oxide (no) pada tikus (Studi pada tikus rattus novergicus strain wistar jantan terpapar inhalasi uap benzene)
Authors: Roziana Roziana , Subagio Hertanto Wahyu , Suhartono Suhartono , Widyastiti Nyoman Suci 
Published: November 2017

Latar Belakang : Paparan benzene dapat menyebabkan stres oksidatif, diantaranya ditandai dengan peningkatan kadar GGT dan kadar NO. Vitamin E dapat mengurangi dan mencegah produksi radikal bebas. Reaktivitas hidrogen fenolik pada kelompok hidroksil α-tokoferol akan menstabilkan elektron tidak berpasangan pada radikal bebas.Tujuan : Membuktikan pengaruh suplementasi vitamin E terhadap kadar GGT dan kadar NO pada tikus jantan terpapar uap benzene.Metode : Penelitian ini adalah penelitian eksperimen pada binatang coba dengan rancangan post test only controlled group design. Sampel 35 ekor tikus strain wistar jantan dibagi secara random dalam enam kelompok yaitu kontrol negatif, kontrol positif dan empat kelompok perlakuan suplementasi vitamin E dosis bertingkat (X1 = 1,8 IU; X2 = 3,6 IU; X3 = 7,2 IU; dan X4 = 14,4 IU per hari untuk setiap 200 gram berat badan tikus). Setiap kelompok kecuali kontrol negatif dipapar 300 ppm uap benzene selama 2 minggu (6 hari/minggu, 6 jam/hari). Pengukuran kadar GGT menggunakan metoda Kinetik Colorimetric dan kadar NO menggunakan metoda Colorimetric Gries dilakukan pada setiap kelompok. Hasil : Suplementasi vitamin E berpengaruh menurunkan kadar GGT (p=0,0001). Pengaruh paparan benzene terhadap peningkatan kadar GGT dapat dicegah dengan baik pada dosis suplementasi vitamin E 14,4 IU/200gr BB tikus/hari. Suplementasi vitamin E tidak berpengaruh terhadap kadar NO.Simpulan : Ada pengaruh suplementasi vitamin E terhadap penurunan kadar GGT dan tidak ada pengaruh suplementasi vitamin E terhadap penurunan kadar NO.
Peran modul MP-ASI dalam perilaku pemberian MP-ASI pada ibu anak bawah dua tahun (BADUTA)
Authors: SP Sri Hapsari , Margawati Ani , Nugraheni SA. 
Published: November 2017

Background : Lack of complementary feeding behavior is one of the problems in Indonesia. Nutrition education about complementary feeding among mother from infants aged 6-24 months should be carried out to support compelementary feeding behavior. Module with an easily language punctuated by images and can be learned at home is expected to incerase complementary feeding behavior among mothers from child under two years old.Method : The design of this research was quasi-experimental with non-randomized pre-test and post-test control group design. Training of complementary feedings module were given for four meetings. The annalyze were conducted by SPSS program. Result : This study found that the median age of subjects between two group are adults. The median duration of education are 9 years. There was no difference of Financial families outcome in the both of groups is low. Nutrition education with module can increase complementary feeding behavior at intervention group and the improvement of this scores better than control group. Complementary feeding behavior retention increased significant among 2 weeks and 1 month after intervention.Conclusion : Nutrition education with module contribute to improve complementary feeding behavior among mothers from child under two years old.
Star-forming complexes in the polar ring galaxy NGC660
Authors: Smirnova Ksenia I. , Wiebe Dmitri S. , Moiseev Alexei V. 
Published: November 2017

Abstract
Galaxies with polar rings consist of two subsystems, a disk and a ring, which rotate almost in orthogonal planes. In this paper, we analyze the parameters characterizing the composition of the interstellar medium and star formation in star-forming complexes belonging to polar ring galaxy NGC660. We show that star-forming regions in the ring of the galaxy are distinctly different from those in the galaxy disk. They possess substantially lower infrared luminosities, which is indicative of less dust mass in these regions than in a typical disk star-forming region. UV and Hα luminosities also appear to be lower in the ring, which is likely a consequence of its relatively recent formation.
Last Copies Initiative: Permanent Conservation of Print Collection in Canada
Authors: Gamache Pierre 
Published: November 2017

AbstractThis article is a written version of the presentation “Last Copies Initiative: Permanent Conservation of Print Collections in Canada” made in November 2016 in Göttingen, Germany. This article describes the Canadian context that enabled this initiative, its success in the development of its framework, and the issues it faced in its implementation. It concludes on lessons learned and next steps.
Optimization of melon oil methyl ester production using response surface methodology
Authors: Aliozo O. S. , Emembolu L. N. , Onukwuli O. D. 
Published: November 2017

Abstract
In this research work, melon oil was used as feedstock for methyl ester production. The research was aimed at optimizing the reaction conditions for methyl ester yield from the oil. Response surface methodology (RSM), based on a five level, four variable central composite designs (CCD)was used to optimize and statistically analyze the interaction effect of the process parameter during the biodiesel production processes. A total of 30 experiments were conducted to study the effect of methanol to oil molar ratio, catalyst weight, temperature and reaction time. The optimal yield of biodiesel from melon oil was found to be 94.9% under the following reaction conditions: catalyst weight - 0.8%, methanol to oil molar ratio - 6:1, temperature - 55°C and reaction time of 60mins. The quality of methyl ester produced at these conditions was within the American Society for Testing and Materials (ASTM D6751) specification.
Rental and Management Policy of Municipal Residential Buildings: Housing Policy. Case Study of Riga (Part One)
Authors: Puķītis Armands , Puķīte Iveta , Geipele Ineta 
Published: November 2017

Abstract
The present scientific article is the first part of two publications, where the authors obtain results from the scientific research for municipal residential property legal aspects and housing policy, as well as risks in the maintenance of the housing stock. To ensure the fulfillment of the functions prescribed by law in relation to the provision of living space, each municipality owns a number of rental apartments. Some municipalities even build special dwellings aimed to fulfil this function. Housing management involves the implementation of a specific process prescribed by both the law and the principles of good governance. However, all management processes are subject to risks that can endanger the implementation of the entire management process. To ensure efficient and high-quality maintenance of the management process, risk assessment is required. In order to successfully implement all these activities, first of all, there is a need for a legal framework that will stipulate the obligations, responsibilities, rights of the persons involved, as well as a series of measures that determine the actions to be taken to ensure the successful maintenance of the housing stock. The aim of the article is to investigate and analyse the regulation of the rent of the legal relations of the municipal property that is used as rental apartments, the management processes of municipal residential property and their compliance with regulatory enactments, as well as to define risks that prevent the efficient and high-quality maintenance of the housing stock.
Porous Metallic Biomaterials Processing (Review) Part 1: Compaction, Sintering Behavior, Properties and Medical Applications
Authors: Popescu Ileana Nicoleta , Vidu Ruxandra , Bratu Vasile 
Published: November 2017

Abstract
Over the last few decades, researchers has been focused on the study of processing using different methods of new biocompatible and/or biodegradable materials such as permanent or temporary medical implants in reconstructive surgery. The advantages of obtaining biomedical implants by Powder Metallurgy (P/M) techniques are (i) obtaining the near-net-shaped with complex forms, (ii) making materials with controlled porosity or (iii) making mechanically resistant sintered metallic materials used as reinforcing elements for ceramic/polymeric biocompatible materials. In this first part of the 2-part review, the most used and newest metallic biomaterials obtained by P/M methods are presented, along with their compaction and sintering behavior and the properties of the porous biomaterials studied in correlation with the biomedical domain of application.
Literature as a Political Tool: Whig Efforts to Prevent the Election of Martin Van Buren
Authors: Pecina Jozef 
Published: November 2017

Abstract
Starting with Andrew Jackson, presidential candidates in the United States used campaign biographies as useful political tools, and since 1824 no presidential election year has passed without a campaign biography. Martin Van Buren, President Jackson’s successor in the White House, became a target of a vicious campaign intended to prevent his election. His Whig opponents used a number of literary genres to slander him, including a mock campaign biography and a novel. The article focuses on the portrayal of Martin Van Buren in The Life of Martin Van Buren, allegedly written by Davy Crockett in 1835, and a novel named The Partisan Leader; A Tale of the Future, written by Nathaniel Beverley Tucker in 1836. Though being of different genres, these curious and obscure works have certain things in common - they were written under pseudonyms, their main goal was to prevent the election of Martin Van Buren and both of them failed in their goal.
“Cinematic” Gravity’s Rainbow: Indiscernibility of the Actual and the Virtual
Authors: Grmusa Lovorka Gruic 
Published: November 2017

Abstract
Acknowledging that all media interpenetrate without any one being privileged as original, this paper focuses on the influence and omnipresence of screen technologies, cinematography in particular, asserting its capacities to act as a dominant technological and cultural force, which surveys and controls the economy, affects human consciousness, and implements its own ideologically tainted reality. More specifically, the analysis demonstrates the impact of cinematography within Thomas Pynchon’s Gravity’s Rainbow, emphasizing intermedial reflexivity from screen to paper, its unfolding and animation, representations and mutations, but also the notion that virtuality dominates actuality (Virilio, The Vision 63), or, in Deleuze’s terms, the two coalesce within the crystal-image, for the real and the imaginary, the actual and the virtual, although distinct, are indiscernible (Deleuze, Cinema 2 68-69). The study is grounded in Paul Virilio’s theoretical framework and his criticism of the colonization of the real by the virtual, and in Gilles Deleuze’s account on cinematic taxonomy and how cinematography partakes in the emergence of a new notion of reality and history. By appropriating, repurposing, and reshaping the techniques, forms, and contents of cinematography, and at the same time being critical of its effects, Pynchon uses paper surface for transition of his ideas, validating the repercussions of intermediation as a cultural force and unveiling literature’s performativity, its ability to shelter/entertain the “cinematic,” which in turn revolutionizes and animates fiction.
Analytical Model Development for Unified 2D Electron Gas Sheet Charge Density of AlInN/GaN MOSHEMT
Authors: Amarnath Gaini , Lenka Trupti Ranjan 
Published: November 2017

Abstract
We have developed a unified analytical model for computation of 2D electron gas sheet charge density in AlInN/GaN metal-oxide-semiconductor high electron mobility transistor device structure. This model has been developed by incorporating the variation in lowest three energy sub-bands and Fermi level energy in the quantum-well with respect to gate voltage. We noticed that the dependency of lowest sub-band energy with Fermi energy having two fields, which are the lowest sub-band energy is greater and lesser than the Fermi level energy. According to these two fields, we have developed the fermi energy and sheet charge density expressions in each field. By combining each field of the models, developed a unified 2D electron gas sheet charge density model. The Fermi level and sheet charge density are interdependent in the model development. The developed model results are compared with TCAD simulation results and obtain a good consistency between them. This model is fitted to other metal-oxide-semiconductor high electron mobility transistor devices also with modifications in related physical values.