bluuebunny/crossref_metadata_2025_split huggingface dataset:
Limit-point criteria for polynomials in a non-oscillatory expression
Authors: Read T. T. 
Published: July 2016

SynopsisSeveral criteria are given for some or all polynomials in an expression M(y) = –(py′)′+qy which is non-oscillatory on (0, ∞) to be limit-point. One of these states that if M is non-oscillatory and , then every polynomial in M is limit-point.
The non-monotonicity of solutions in swirling flow
Authors: McLeod J. B. , Parter S. V. 
Published: July 2016

SynopsisThis paper studies the boundary-value problem arising from the behaviour of a fluid occupying the region 0 ≦ x ≧ 1 between two rotating discs, rotating about a common axis perpendicular to their planes, when the discs, are rotating in the same sense with speeds 0 ≦ Ω0<Ω1. The equations which describe the axially symmetric similarity solutions of this problem arewith the boundary conditionswhere ε = v/2Ω1 and v is the kinematic viscosity.The major result is: There is an ε0 such that for 0<ε≦ε0 there does not exist a solution 〈H(x,ε), G(x,ε)〉 with G′(x,ε)≧0.
The limit-point, limit-circle nature of rapidly oscillating potentials
Authors: Atkinson F. V. , Eastham M. S. P. , McLeod J. B. 
Published: July 2016

SynopsisThe Weyl limit-point, limit-circle nature of the equation y″(x)–q(x)y(x) = 0(0≦ x< ∞) is analysed When q(x) has the form q(x) = xαp(xβ), where α and β are positive constants and p(t) is a continuous periodic function of t.
Second-order differential expressions whose squares are limit-3
Authors: Eastham M. S. P. , Zettl A. 
Published: July 2016

SynopsisSecond-order expressions –d2/dx2+qwhose squares are of limit-3 type are constructed. The construction is simpler than others in the literature. The functionqcan be chosen to be infinitely differentiable and decreasing and to satisfyq(x)≧ –x2(logx)2+ε(x→∞) for a given ε>0.
Strong limit-point and Dirichlet criteria for ordinary differential expressions of order 2n
Authors: Hinton Don 
Published: July 2016

SynopsisConditions are given which ensure that a weighted 2nth order ordinary differential equation on a half-line satisfy the strong limit-point and Dirichlet conditions. Perturbation terms are permitted which either satisfy certain pointwise bounds or integral type bounds. Not all of the coefficients of the equation are required to be non-negative.
The endomorphism near-ring of an infinite dihedral group
Authors: Meldrum J. D. P. 
Published: July 2016

SynopsisIn this paper, we determine the semigroup End D of endomorphisms of the infinite dihedral group D, and give a multiplication table for it. We determine the additive structure of the near-rings E(D) generated by the endomorphisms of D, A(D) generated by the automorphisms of D and I(D) generated by the inner automorphisms of D, and determine their radicals and all their maximal right ideals.
On semilinear elliptic boundary value problems in unbounded domains
Authors: Bose Deb Kumar 
Published: July 2016

SynopsisWe consider the possibility of solving semilinear elliptic boundary value problems in unbounded domains. We first treat the case when the non-linear terms are independent of terms involving gradients. Using a monotone iteration scheme, we show that the existence of a weak subsolution v and a weak supersolution w ≧ v, implies the existence of a weak solution u, and v ≦ u ≦ w. We also state conditions which guarantee the existence of a solution when only a subsolution is known to exist. Next, we suppose the non-linear terms can depend on gradient terms. Using a method developed in [4], based on perturbation theory of maximal monotone operators, we prove the existence of a H2(Ω) solution lying between a given H2(Ω) subsolution v and a given H2(Ω) supersolution w ≧ v.
Toxocara Canis infestation with encephalitis
Authors: Mikhael Nadia Z. , Montpetit Vital J.A. , Orizaga Manuel , Rowsell Harry C. , Richard Michael T. 
Published: July 2016

SUMMARYThe syndrome “visceral larva migrans” produced by migration of nematode larvae (commonly Toxocara species) in the extraintestinal tissues in unusual hosts, including man (particularly children of dirt eating age), with the production of reactive granulomatous lesions, was first described in 1952. About 200 cases have been reported since. Well documented cases are rare due to the difficulty in histological verification. Three cases have been reported in Canada but these were not verified. We believe the present report is the first verified case of visceral larva migrans in Canada and the fifth case of human cerebral involvement by Toxocara in the English literature. It is hoped that this report will emphasize the need for further research into the role of host versus parasite and will underline the potential danger, albeit remote, of household pets to children. Indeed, prevention is the only line of attack, as there is no effective drug against the migrating larvae of Toxocara.
HL-A Frequencies in Patients with Multiple Sclerosis
Authors: Paty D.W. , Mervart H. , Campling B. , Rand C.G. , Stiller C.R. 
Published: July 2016

SUMMARY:The histocompatibility antigens (HL-A) have been determined in 100 multiple sclerosis (M.S.) patients and 143 randomly selected controls. In the M.S. group there was a statistically significant increase in the frequency of HL-A 7 and W 18 with an insignificant increase in HL-A 3. The variance from normal HL-A patterns in the M.S. population may play some role in establishing the substrate for this disease. Studies in experimental animals have shown that susceptibility to autoimmune disease and to virus infection is linked to the major histocompatibility locus. This has interesting implications for both the “slow virus” and the “autoimmune” theories of the etiology of multiple sclerosis.
Relative Prognostic Significance of Vasospasm Following Subarachnoid Hemorrhage
Authors: Weir Bryce , Rothberg Charles , Grace Michael , Davis Faye 
Published: July 2016

SUMMARY:A retrospective analysis of 274 patients with intracranial aneurysms, diagnosed either angiographically or at autopsy between 1968 and 1973 at the University of Alberta, was carried out. One hundred and forty-six patients had intracranial clipping of the aneurysm. Clinical and radiologic data were abstracted from the chart and the angiographic studies. Probability of survival curves were constructed. Associations between various clinical factors and survival at two months were demonstrated. The most important prognostic factors were the clinical grade at angiography or surgery, followed by the presence of preoperative spasm, hematoma or focal edema, elevated blood pressure on admission, time interval from hemorrhage to surgery and age. The data lends some support to the policy of operating on patients in good neurological condition, even if their pre-operative angiogram shows spasm.
The Nature of Primary Vocal Tremor
Authors: Hachinski V.C. , Thomsen I.V. , Buch N.H. 
Published: July 2016

SUMMARY:Three elderly women with marked progressive voice tremor, without other neurological symptoms, and negative family histories were investigated.All had a 4-5 Hz respiratory tremor in expiration and, to a lesser degree, in inspiration; and all had vocal tremulousness synchronous with their respiratory irregularity. Articulation of phonemes was normal. In two cases the neurological examination was otherwise normal; in the third case there was a minimal 7½ Hz tremor in the left thumb and index finger.Simultaneous speech and vocal air pressure recordings, as well as cinematographic studies of the vocal apparatus and diaphragm were carried out.It is suggested that these cases represent primarily an action tremor of respiration, that they belong in the spectrum of essential tremor, and hence may be amenable to treatment with propranolol.
Laying the Ghost of ‘Muscles Versus Movements’
Authors: Phillips C.G. 
Published: July 2016

It is certainly a mark of great wisdom to the organizer of this meeting to have chosen Charles Phillips as our Guest Lecturer for this meeting.Whilst I am grateful for this opportunity of saying a few words of introduction, I am sure it can be said of Charles Phillips that very little introduction is necessary, since we meet him at the most important meetings in Neurophysiology around the world. Any meeting on the motor system, of course, is not complete without the participation of Dr. Phillips. However, some of the less old-timers than myself, and the students, might be interested in the beginnings of Dr. Phillips’ career in neurophysiology and to know that he was first a clinical neurologist beginning his medical studies in Oxford just before the war, where he came under the influence of Sir Charles Sherrington with Jack Eccles as his tutor.
Clinical Problems of Motor System Disease
Authors: Richardson J.C. 
Published: July 2016

SUMMARY:This prologue to a symposium of research studies on motor mechanisms is a general commentary by a clinical neurologist. The vast extent and intricacy of modern basic neurological scientific knowledge presents a rather bewildering challenge to reasonable clinical application. In some degree this is being handled by complex and diverse neurological subspecialization. It is recalled that many past advances in the knowledge of neurological disease were achieved by a series of alternating and supporting bedside and laboratory observations and studies.The varied disorders of movement and muscle tone which signal disordered motor mechanisms will continue to demand explanation and will keep the human model in a leading research position. Clinical and laboratory research leading to part discoveries of mechanisms of disease is sometimes productive of dramatic new means of therapy. The story of Wilson’s disease is briefly reviewed in that context. Some recent studies on hypoxic myoclonus are described with the evidence of a serotonin defect and useful related therapy.
Physiopathology of Experimental Parkinsonism in the Monkey
Authors: Poirier Louis J. , Filion Michel , Larochelle Louis , Péchadre Jean-Claude 
Published: July 2016

SUMMARY:Postural or Parkinson-like tremor, which results from the impairment of mechanisms which are predominantly lateralized in the brain, is most likely related to the combined impairment of the dopaminergic nigrostriatal pathway and the corresponding rubro-olivo-cerebello-rubral loop (without excluding the possibility that other nervous mechanisms interconnected with these structures may represent an alternative disturbance). The integrity of the internal division of the pallidum and the ventrolateral area of the thalamus and their efferent fibers as well as the motor cortex and certain of its cortico-subcortico-spinal pathways (Figures 1 and 2) is apparently an essential feature for the elaboration of the rhythmic bursts associated with the appearance of postural tremor. The integrity of the spinal sensory roots and the rubro-tegmentospinal tract is not a prerequisite for the expression of postural tremor, a condition which seems essential for the production of rigidity. The latter facts suggest that the disturbances which subserve these two types of motor impairment, often concomitantly present in Parkinsonism, partially involve the impairment of different mechanisms although the loss of the DA fibers originating in the substantia nigra and ending in the neostriatum (Figure 1) appears to represent a disturbance common to both types of disorders.Bradykinesia which may be associated with an impairment of catecholamine metabolism (and more especially the neostriatal DA mechanisms) on both sides of the brain may also result from bilateral lesions of the pallidum or of its outflow corresponding, in the main, to the pallidothalamic fibers ending in the ventrolateral thalamus. The latter types of lesion most likely exclude the influence of the monoaminergic, cholinergic and gabaminergic activities normally originating in the striopallidal system and influencing the activity transmitted to other CNS mechanisms. Severe akinesia, however, apparently depends on more profound and generalized disturbances of brain monoamine metabolism with or without the involvement of other ill-defined mechanisms. At any rate the impairment of the brain DA mechanisms (and especially those of the neostriatum) seems to represent a major feature in the production of the Parkinsonian type of akinesia. Further work is needed to establish the relative importance of the loss of catecholaminergic mechanisms other than those of the neostriatum in the production of akinesia.
Congenital Displacement of Temporal Cortex into the Central Spinal Canal
Authors: Silver David A. , Robertson David M. 
Published: July 2016

SUMMARY:This is a report of the first recorded observation of displacement of temporal cortex into the central spinal canal in an infant with the Arnold Chiari malformation, platybasia, aqueductal atresia, hydrocephalus and meningomyelocele. The combination of an absent tentorium, absent right cerebellar hemisphere and malformed fourth ventricular roof provided the anatomical background for this unique event.
Recurrent Spontaneous Seizure State Induced by Prefrontal Kindling in Senegalese Baboons, Papio Papio
Authors: Wada J.A. , Osawa T. , Mizoguchi T. 
Published: July 2016

SUMMARY:In our earlier study of amygdaloid kindling in Papio papio (Pp), the development of partial complex seizure and of focal motor seizure was correlated with bifrontal theta discharge and increasing Rolandic spike discharge respectively and the final stage was characterized by primary generalized convulsive seizure. Since the latter seizure pattern is known to originate from the frontal focus in man, the frontal cortex became suspect in the development of the final stage seizure pattern. Daily prefrontal stimulation showed that Pp can be kindled from this site, culminating in a recurrent spontaneous seizure state identical to that induced by amygdaloid kindling in this species. However, our observation did not support our original assumption regarding the genesis of primary generalized convulsive seizure. Prefrontal and amygdaloid kindling are significantly different with respect to morphology, distribution and propagation of afterdischarge and interictal spike discharge, and speed and pattern of clinical seizure development. Most intriguingly, inter-ictal behavioral aberration associated with depth EEG changes was observed only in the prefrontal animals and not in the amygdaloid animals.
Frontal Lobe and Kindling in the Rat
Authors: Corcoran Michael E. , Urstad Harald , McCaughran James A. , Wada Juhn A. 
Published: July 2016

SUMMARY:To test the hypothesis that the cortex participates in amygdaloid kindling in rats, bilateral aspiration lesions were made in various cortical areas in rats prior to kindling. Lesions in orbital cortex (on the dorsal lip of the rhinal sulcus) or prefrontal cortex (area 10) significantly retarded the rate of amygdaloid kindling; lesions in motor cortex, anterior cingulate cortex, or visual cortex were without effect. Detailed analysis indicated that the orbital lesioned and frontal-lesioned rats kindled relatively normally up to the second-last stage of amygdaloid kindling, in which stage they perseverated significantly longer than the controls and the other lesioned rats. These results suggest that areas of the frontal lobe participate in the elaboration and generalization of amygdaloid seizures in rats. Although retarded in rate, kindling nonetheless occurred in the lesioned rats, indicating that these cortical areas are not essential for the development of amygdaloid seizures.
Anesthetic Barbiturates in Refractory Status Epilepticus
Authors: Young G.B. , Blume W.T. , Bolton C.F. , Warren K.G. 
Published: July 2016

SUMMARY:Two patients with previous cerebral damage and seizures and three patients with acute inflammatory cerebral lesions developed status epilepticus. They were unresponsive to standard anticonvulsants, but anesthetic barbiturates (thiopental and pentobarbital) stopped the seizures promptly.
Bilateral Symmetrical Brain Lesions in Tricyclic Antidepressant Overdosage
Authors: Sabet Laila M. 
Published: July 2016

SUMMARY:The cerebral pathology in a case of tricyclic antidepressant overdose by amitriptyline is described. A review of the literature of similar cases is summarized. The relation of the cerebral lesions to the development of a hypertensive episode possibly induced by amitriptyline is discussed.
Glycosylated Hemoglobins In Friedreich's Ataxia
Authors: Draper P. , Shapcott D. , Langlois M. , Lemieux B. 
Published: July 2016

SUMMARY:In a study of glycosylated hemoglobins in Friedreich's Ataxia patients and in family members, the level was found to be higher in insulin dependent diabetics than in healthy non-diabetic control subjects (p<0.01), but was similar to non-ataxic diabetic control subjects. Results for non-diabetic Friedreich's Ataxia patients and siblings were similar to those for non-diabetic control subjects while levels were slightly increased in the heterozygotes. It is concluded that in Friedreich's Ataxia patients and family members (apart from the insulin dependent diabetics), there was no hyperglycemia sufficient to be detected as an increase in glycosylated hemoglobins.
Lecithin: Cholesterol Acyltransferase Activity and Fatty Acid Composition of Erythrocyte Phospholipids in Friedreich's Ataxia
Authors: Huang Y.S. , Marcel Y.L. , Vezina C. , Barbeau A. , Davignon J. 
Published: July 2016

SUMMARY:In a study of the fatty acid composition of erythrocyte membrane phospholipids in Friedreich's ataxia, a lower percentage of linoleic acid in phosphatidylcholine was demonstrated. An enzyme involving the exchange of lipids between plasma and erythrocyte membrane, lecithin: cholesteryl acyltransferase (LCAT) was also studied. It was found that the LCA Tactivity had a trend towards low values. However, crossing-over studies indicated that when the LCAT enzyme of patients was exposed to its own substrate it gave low activity values but that the result reverted to normal when control substrate was used
Effects of Glutamate and Aspartate on Ataxic Gait Induced by 3-Acetyl Pyridine in Rats
Authors: De Michele G. , Jolicoeur F.B. , Rondeau D.B. , Butterworth R.F. , Barbeau A. 
Published: July 2016

SUMMARY:The main purpose of this study was to examine the effects of intraventricular injections of glutamate and aspartate on the walking gait of rendered ataxic by the administration of 3-acetyl pyridine. Both amino acids significantly improved the walking gait of these animals. The effects of other substances known to have a stimulatory influence on locomotor activity in rats were also investigated. Amphetamine, apomorphine and thyrotropin releasing hormone (TRH) had no effect on the ataxic gait of 3-AP treated animals. Substance P significantly improved the gait of ataxic animals, but to a lesser extent than that seen with glutamate and aspartate.
Friedreich's Ataxia 1980 An Overview of the Physiopathology
Authors: Barbeau André 
Published: July 2016

SUMMARY:Phase three of the Quebec Cooperative Study of Friedreich's Ataxia was devoted to an understanding of the physiopathology of individual symptoms on the basis of previously discovered biochemical leads. The present paper attempts to pull these results together by presenting, as a hypothesis, a unifying scheme of possible interactions and relationships. The central core of this hypothesis is the demonstration in Friedreich's ataxia of a state of mitochondrial energy deprivation. This is indirectly responsible for such associated and important symptoms as muscle weakness, dying-back neuropathy, scoliosis and hypertrophic cardiomyopathy. Secondarily, and possibly as an independent but linkedevent, the entry of glucose into cells and pyruvate oxidation, are slowed down, favoring the development of diabetes. As a consequence, tissue concentrations of glutamic acid and aspartic acid are decreased, particularly in more vulnerable areas such as the cerebellum, brain stem and dorsal root ganglia. This tissue deficiency in putative excitatory neurotransmitters is directly responsible for the symptom of ataxia. This conclusion is reinforced by the correction of the ataxia in glutaexperimental animals, by the intraventricular injection of the same amino acids, and not by the injection of other stimulants of motricity. The observed mitochondrial energy deprivation could be the metabolic consequence of major changes in the linoleic acid (18:2) composition of inner mitochondrial membrane phospholipids, such as cardiolipin. Such decreases in membrane 18:2 could be the result of interference with the normal incorporation of this fatty acid to lipoproteins and/or cell membranes. It is at this level that the search for the specific enzyme defect in Friedreich's ataxia is continuing.
Migraines Inhabituelles
Authors: Roy Louis E. 
Published: July 2016

SUMMARY:From 123 hospital charts with a diagnosis of migraine, seen between the years 1974 and 1978, ten cases have been selected of complicated migraine and three cases of migraine with special features. A review, and a discussion of the clinical characteristics, and of the treatment of these unusual migraines has been made. The three cases with special features include migraine in association with hyperlipidemia, with Raynaud's disease and with meningioma.
The Relationship Between Cerebral Blood Flow and the EEG in Normals
Authors: Menon Devidas , Koles Zoltan , Dobbs Allen 
Published: July 2016

SUMMARY:Using the Xel33 inhalation technique, measurements of the blood flow to the left and right parietal and temporal regions of the cerebrum were obtained in 5 healthy individuals while simultaneously recording their EEGs. Up to 3 measurements were obtained from each of the subjects the first while they were mentally at rest and the others while they were engaged in prescribed forms of mental activity. Relationships between the measured blood flow through grey matter, initial slope index, relative grey weight, percent grey flow and power in the delta, delta-theta, alpha, beta and gamma rhythms of the EEG were examined. The results showed that for the subject group as a whole there was a strong correlation between the power present in the low frequency components of EEG and the grey flow and relative grey weight parameters of blood flow. On an individual basis, the observed relationships were highly variable particularly at high flow rates and at low relative grey weights, but became much more definitive at low flows and high weights. The results as they relate to previous work of this kind are discussed.
Oculodermal Melanosis (Naevus of Ota) Complicated by Multiple Intracranial Tumors
Authors: Horsey W.J. , Bilbao J.M. , Nethercott J. , Myers R. , Hoffman H.J. 
Published: July 2016

A thirty-seven year old, East Indian female was admitted to St. Michael's Hospital on July 26, 1979 complaining of headache, diplopia, nausea and vomiting.In April of 1978 she was referred to a neurologist for investigation of headache. Neurological examination was normal. An X-ray of her skull revealed a lytic lesion, 2 cms. in diameter, in the right frontal area. A bone scan showed no abnormality. Further study was refused. A left facial “birth mark” was noted.