bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vaccines and allergy: Back to the right places
Authors: Moschese Viviana , Montin Davide , Ottaviano Giorgio , Sgrulletti Mayla , Beni Alessandra , Costagliola Giorgio , Sangerardi Maria , Santilli Veronica , Miraglia Del Giudice Michele , Rizzo Caterina , Martire Baldassarre ,   within the Italian Society of Pediatric Allergology and Immunology (SIAIP) Vaccine Committee
Published: September 2024

AbstractHypersensitivity reactions represent one of the most common causes of hesitancy for adherence to national vaccination programs. The majority of hypersensitivity reactions after vaccination are mild, and anaphylaxis is reported to be rare, although it remains challenging to estimate the frequency attributed to each single vaccine, either because of the lower number of administered doses of less common vaccines, or the administration of simultaneous vaccine in most of the vaccination programs. Although literature remains scattered, international consensus guides clinicians in identifying patients who might need the administration of vaccines in protected environments due to demonstrated hypersensitivity to vaccine components or adjuvants. Here we provide the current guidance on hypersensitivity reactions to vaccines and on vaccination of children with allergy disorders.
A review of the perioperative management of direct oral anticoagulants for pediatric anesthesiologists
Authors: Furman Kara , Giustini Andrew , Branstetter Joshua , Woods Gary , Downey Laura A. 
Published: September 2024

AbstractBackgroundAlthough direct oral anticoagulants (DOACs) have been used in the adult population for over a decade, DOACs use has begun to rise in pediatric populations since FDA approval of rivaroxaban and dabigatran, DOACs offer several advantages for pediatric patients, to other anticoagulants, including a similar safety profile, minimal lab monitoring, and ease of administration. The rise in DOAC use has led to an increasing number of pediatric patients managed on DOACs presenting for elective and urgent procedures. Perioperative management of anticoagulation is often challenging for providers due to the lack of expert consensus guidelines and the difficulty in balancing a patient's thrombotic risk with bleeding risk for a given procedure.AimsUsing the most up to date literature, we provide a focused review on the perioperative management of DOACs in pediatric patients.ConclusionsThis work presents a focused review for pediatric anesthesiologists on clinically available DOACs, perioperative monitoring and management of DOACs, as well as options and indications for reversal. While consensus expert practice guidelines are still needed, we hope this work will familiarize perioperative physicians with these agents, recommended uses, and potential perioperative management.
Perioperative anesthetic management of patients with hypoplastic left heart syndrome undergoing the comprehensive stage II surgery—A review of 148 cases
Authors: Müller Matthias , Lurz Florian , Zajonz Thomas , Edinger Fabian , Yörüker Uygar , Thul Josef , Schranz Dietmar , Akintürk Hakan 
Published: September 2024

AbstractBackgroundPatients with hypoplastic left heart syndrome undergo the comprehensive stage 2 procedure as the second stage in the hybrid approach toward Fontan circulation. The complexity of comprehensive stage 2 procedure is considered a potential limitation, and limited information is available on its anesthetic management. This study aims to address this gap.MethodsA single‐center retrospective cohort study analyzed 148 HLHS patients who underwent comprehensive stage 2 procedure, divided into Group A (stable condition, n = 116) and Group B (requiring preoperative intravenous inotropic therapy, n = 32). Demographic data, intraoperative hemodynamics, anesthetic management, and postoperative outcomes were collected.ResultsEtomidate (40%) was the most common induction agent, followed by esketamine (24%), midazolam (16%), and propofol (13%). Inhaled induction was rarely necessary (2%), occurring only in Group A patients. No statistical differences were found between groups for induction drug choice. Post‐cardiopulmonary bypass management included moderate hypoventilation, inhaled nitric oxide (100%), and hemodynamic support with milrinone (97%) and norepinephrine (77%). Group B patients more frequently required additional levosimendan (20%) and epinephrine (18%). Extracorporeal membrane oxygenation was necessary in 8 patients (5%) with no between‐group differences. Switching from fentanyl to remifentanil reduced postoperative ventilation time overall. However, Group B experienced significantly longer ventilation (6.3 vs. 3.5 h) and ICU stay (22 vs. 14 days). In‐hospital mortality was 5% overall (Group A: 4%, Group B: 9%). Long‐term survival analysis revealed a significant advantage for Group A.ConclusionThe use of short‐acting opioids and adjusted ventilation modes enables optimal pulmonary blood flow and rapid transition to spontaneous breathing. Differentiated hemodynamic support with milrinone, norepinephrine, supplemented by levosimendan and epinephrine in high‐risk patients, can mitigate the effects on the preoperatively volume‐loaded right ventricle. However, differences in long‐term survival probability were observed between groups.Trial RegistrationLocal ethics committee, Medical Faculty, Justus‐Liebig‐University‐Giessen (Trial Code Number: 216/14).
You cannot spell risk without “I‐S”: The disclosure of information systems risks by Fortune 1000 firms
Authors: Whitaker Jonathan , Thekdi Shital 
Published: September 2024

AbstractCybersecurity events can cause business disruptions, health and safety repercussions, financial costs, and negative publicity for large firms, and executives rank cybersecurity as a top operational concern. Although cybersecurity may be the most publicized information systems (IS) risk, large firms face a range of IS risks. Over the past three decades, researchers developed frameworks to categorize and evaluate IS risks. However, there have been few updates to these frameworks despite numerous technological advances, and we are not aware of any research that uses empirical data to map actual IS risks cited by large firms to these frameworks. To address this gap, we coded and analyzed text data from Item 1A (Risk Factors) of the fiscal year 2020 Securities and Exchange Commission Forms 10‐K for all Fortune 1000 firms. We build on prior research to develop a framework that places 25 IS risks into four quadrants and 10 categories, and we record the number and type of IS risks cited by each firm. The risk of cyberattack is cited by virtually all Fortune 1000 firms, and the risk of software/hardware failure is cited by 90% of Fortune 1000 firms. Risks associated with data privacy law compliance are cited by 70% of Fortune 1000 firms, and risks associated with internet/telecommunications/power outage, human error, and natural disasters/terrorism are cited by 60% of Fortune 1000 firms. We perform additional analysis to identify differences in risk citation based on industry and financial measures.
Exploring dynamic public trust in mega infrastructure projects during online public opinion crises of extreme climate emergencies: Users’ behaviors, trust dimensions, and effectiveness of strategies
Authors: Wang Yang , Gong Ruoyan , Xu Peizhi , Shen Chen 
Published: September 2024

AbstractThe vulnerability of mega infrastructure projects (MIPs) has generated online public opinion crises, leading to public trust damage. However, few studies focused on the online dynamic trust of MIPs in such crises from the perspective of multiple users. Based on situational crisis communication theory, this study aims to explore the dynamic public trust in MIPs during online public opinion crises of extreme climate emergencies. The extreme heavy rainstorm event in Zhengzhou City, China, was selected as the case. Content analysis, the curve fitting method, and sentiment analysis were conducted to process the collected data from multiple users. The results indicated that the opinions of trust damage were set by “media practitioners” and led by “elites,” whereas the opinions of trust repair were directed by “elites,” led by “media practitioners,” and defended by “individuals.” Besides, trust dimensions would change over time; integrity‐based and competence‐based trust diffused alternatively. “Diminish,” “deny,” and “rebuild” strategies were proved to be the most effective strategies in integrity‐based, competence‐based, and competence and integrity–based trust repair, respectively. The findings can contribute to the authorities monitoring online public opinions in extreme climate emergencies and repairing trustworthy images.
The Use and Impact of Well‐Being Metrics on Policymaking: Developers' and Users' Perspectives in Scotland and Italy
Authors: Battaglia Fabio 
Published: September 2024

ABSTRACTGross domestic product (GDP) is frequently used as a proxy for well‐being. Such use of GDP is problematic for many reasons, for GDP excludes activities that contribute to well‐being and includes others that have a negative impact instead. As a result, a vast array of metrics has been developed to complement or replace it and put well‐being at the heart of policymaking. Nonetheless, previous research has shown that their use and impact on policymaking has been limited. This article examines the use and impact of well‐being metrics according to their own developers and intended users in the crucial cases of Scotland and Italy, focusing specifically on the two countries' official well‐being frameworks. Despite being at the forefront of the well‐being debate, both countries have never been studied in this regard before. This article fills this gap, collating views from more than 100 stakeholders, including statisticians, members of interest groups, policymakers and journalists. Findings show that the vast majority of informants could not cite any examples of cases in which either framework impacted on policymaking, or in which they themselves had used these. In some cases, this was due to them not being aware of what such frameworks were in the first place. Those who could identify some examples were those who were or used to be part of the government. Examples would, however, tend to be vague, in some instances remarkable yet merely anecdotal, and still in others the result of an ‘ex‐post rationalisation’.
Improving recognition of early clinical decline: Determining reliability and validity of the Garvey clinical warning curves
Authors: Garvey Paula K. , Himes Hannah , Sampson Marlene , McNett Molly 
Published: September 2024

AbstractBackgroundNew graduate nurses have difficulty recognizing and managing the early signs of clinical decline, resulting in a Failure to Rescue (FTR) event and preventable patient death. To address this gap, Garvey developed a series of Clinical Warning Curves as an instructional tool for new graduate nurses in an academic medical center. The Garvey Clinical Warning Curve models depict the progression of clinical changes in six body systems that occur before cardiac arrest.AimsThe purpose of this study was to establish the content validity, reliability, and usability of the Garvey Clinical Warning Curves among healthcare experts and new‐graduate nurses.MethodsThe current study was a cross‐sectional, observational, validation survey design. Content experts used the content validity index (CVI) to evaluate the Curves.ResultsAll but the temperature curves were rated as “acceptable” (CVI >0.60) for relevance, clarity, and ambiguity. The new graduate nurses who reviewed the case studies and placed patients onto the Clinical Warning Curves did so similarly, generating high intraclass correlation (ICC) scores. The usability survey components measured the perceptions of acceptability, appropriateness, and feasibility for the use of the six Clinical Warning Curves in practice settings. All components of the Curves had an average score of 4.0 or greater except for the level of complexity which scored 3.88.Linking Evidence to ActionThe Garvey Clinical Warning Curves emerged as valid and reliable tools that aid new graduate nurses in recognizing subtle signs of clinical decline. Because timely recognition and communication of clinical decline are key to preventing FTR events and avoiding patient deaths, it would be beneficial to provide the Clinical Warning Curves as a bedside resource for new graduate nurses during their orientation to the unit or within a nurse residency program.
Life Cycle Impact Assessment (LCIA), A Decision Making Approach in Waste Water Treatment Plant: A Case Study
Authors: Kushwah Anand , Jangir Vikas , Sundriyal Sanjay , Paswan Kamlesh , Kumar Ajay 
Published: September 2024

Environmental foot print of a waste water treatment plant is an important criterion to assess the performance of treatment unit. The novel waste water treatment technology was used to clean waste water up to a certain limit. Therefore, in whole process, beginning from electricity production to final disposal of water these treatment technologies can affect our environment. This environmental foot print can be determined by using CML 2000 guideline. In final performance of a waste water treatment plant environmental ill effects should also be incorporated instead of only using treatment efficiency, CML 2000 gives environmental performance. In this study four waste water treatment technologies namely Activated Sludge Process, up flow Anaerobic Sludge Blanket, Membrane Biofilm Bioreactor, Fluidized Aerobic Bed were taken. The environmental performance of all these novel technologies was assessed on the basis of eutrophication, global warming potential and removal efficiency, characterization factors are normalized by using CML 2000 guideline. The maximum and minimum results of Acidification was obtained as 0.2215 & 0.0569 in UASB and FAB respectively. The maximum and minimum results of Eutrophication was attained as 0.564 & 0.055 in MBBR and ASP respectively.
Nijenhuis operators with a unity and F$F$‐manifolds
Authors: Antonov Evgenii I. , Konyaev Andrey Yu. 
Published: September 2024

AbstractThe core object of this paper is a pair , where is a Nijenhuis operator and is a vector field satisfying a specific Lie derivative condition, that is, . Our research unfolds in two parts. In the first part, we establish a splitting theorem for Nijenhuis operators with a unity, offering an effective reduction of their study to cases where has either one real or two complex conjugate eigenvalues at a given point. We further provide the normal forms for ‐regular Nijenhuis operators with a unity around algebraically generic points, along with seminormal forms for dimensions 2 and 3. In the second part, we establish the relationship between Nijenhuis operators with a unity and ‐manifolds. Specifically, we prove that the class of regular ‐manifolds coincides with the class of Nijenhuis manifolds with a cyclic unity. Extending our results from dimension 3, we reveal seminormal forms for corresponding ‐manifolds around singularities.
Gaze Behaviors, Estimated Quiet Eye Characteristics, and Decision Making of Nonexpert Assistant Referees Judging Offside Events in Soccer
Authors: Albaladejo-García Carlos , Luis-del Campo Vicente , Morenas Jesús , Moreno Francisco J. 
Published: September 2024

The study analyzed the gaze behavior and decision-making performance of 20 soccer assistant referees while judging offside events. Specifically, gaze behaviors, gaze entropy, and estimated quiet eye (eQE; defined as the last fixation prior to the attacker’s ball pass) characteristics (i.e., location, onset, offset, and duration) were analyzed in relation to decision-making accuracy. Although a significant number of fixations were observed on the offside line, the highest viewing time corresponded to the ball carrier. The gaze behavior indicated a high distribution of fixations, as evidenced by high stationary gaze entropy (>90%). The assistant referees also distinguished offside from onside positions above chance. However, they displayed nonprolonged eQE on the offside line. As a result, no significant relationships were found between the eQE characteristics and decision-making accuracy. The study concludes that the absence of more functional gaze behaviors, specifically with longer eQE focused on the offside line, impaired the decision-making accuracy of nonexpert assistant referees in soccer.
Moseley Law for Atomic Orbital Exponents
Authors: Tchougréeff A. L. 
Published: September 2024

Abstract
The piecewise linear dependence of orbital exponents $$\xi $$ characterizing either nonorthogonal Slater or orthogonal minimum atomic parameters/Moscow–Aachen–Paris (MAP) radial parts of atomic orbitals is theoretically derived from a plausible model of electronic subshell energy and compared with their values derived from a pragmatic Koga basis set covering the elements from H to Lr ($$Z = 103$$). So derived values of exponents as well follow piecewise linear laws as functions of the nuclear charge $$Z$$. The linear branches of the $$\xi $$ vs. $$Z$$ fairly follow the structure of the Periodic Table being specific for the segments of the $$Z$$ values corresponding to p-, d- and f-elements, respectively. In details, however, the parameters of the theoretical linear dependencies of orbital exponents $$\xi $$ on $$Z$$ and those derived from the pragmatic basis set (referred to as experimental) differ from each other which will be addressed elsewhere.
Highly Stable MOFs-Derived Cu–Co Composite Metal Oxides for Catalytic Oxidation of Toluene
Authors: Jinbo Wang  , Xia Bin , Qin Ruixiang , Zhao Shuai , Qiu Yifang , Li Jing , Wang Yu 
Published: September 2024

Abstract
CuCoOx was prepared by in situ pyrolysis of Cu2+ partially substituted MOF-74 precursor with Co-MOF as a template for catalytic oxidation of toluene. T90 (the temperature corresponding conversion of 90%) was only 212°C, at 1000 ppm toluene and weight hourly space velocity (WHSV) of 36 000 mL g–1 h–1. In addition, the conversion was maintained above 97% for 74 h of continuous reaction at 260°C. Even if after 2400 ppm 1,2-dichloroethane (1,2-DCE) poisoning for 2 h, the toluene conversion was still up to 93%, demonstrating excellent stability and resistance to deactivation of catalyst. Furthermore, The high activity and stability of CuCoOx could be attributed to the large specific surface area as well as the high Co2+/Co3+, Cu2+/Cu+, and Olatt/Oads molar ratios.
The therapeutic effects of Juglans regia Linn (Walnut) extracts on oral Candida infection
Authors: Hamida Talia , Bouderba Nora Nahal , Slimani Alaa 
Published: September 2024

The difficulties associated with oral Candida infection management necessitate the development of novel antifungal medicines in order to widen the spectrum of activity against Candida albicans. The aim of this work is to study the oral anticandidal activity of Juglans regia L. cultivated in Algeria. This plant was chosen due to its traditional use for the treatment of oral infections. Methanolic, ethanolic, butanolic, ethylic acetate and acetonic extracts of the bark of J. regia L. were extracted in a Soxhlet device and screened for in vitro activity against C. albicans. Plant preparations were screened for antifungal activity using a standard agar well diffusion assay. Following a study of the antimicrobial activity of plant extracts, their minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values were determined using a broth microdilution assay. Among J. regia L. extracts, ethylic acetate extract had potent antifungal activity against Candida strain with diameters of inhibition ranging from 15.16±0.76 to 20.83±0.76 mm, followed by acetonic extract with diameters of inhibition ranging from 14.83±0.76 to 19.33±0.28 mm. The J. regia L. demonstrated MIC values ranging from 0.46875 to 3.75 mg mL-1 and the lowest MIC was recorded for ethylic acetate, acetonic extracts and AMB at 0.46875 mg mL-1. The ethylic acetate extract showed the lowest MFC value (0.9375 mg mL-1), followed by butanolic extract (3.125 mg mL-1). These results indicate that J. regia L. bark extracts can contain compounds with therapeutic potential against oral C. albicans and, hence, their possible use as therapeutic agents for oral candidiasis.
Impact of agricultural inputs on the abundance of heavy metals (Cu, Zn) in soil, water, and plants in the south of Algeria
Authors: Guesmia Hadjer , Tarai Nacer , Ouamane A. Tarek , Guimeur Kamel , Masmoudi Ali , Djellouli Amir 
Published: September 2024

he aim of our study is to assess the impact of agricultural inputs on the levels of heavy metals, specifically copper (Cu) and zinc (Zn), in soil, water, and plants in the oasis of El Ghrous, Branis, and Sidi Okba in Algeria. The existence of perilous substances in the surroundings is a significant ecological issue, endangering both human well-being and agricultural output. The overuse of fertilizers and pesticides may be causing heavy metals build-up. The aim will be to highlight a better understanding of the concentrations of copper (Cu) and zinc (Zn), considering as detrimental contaminants, after extensive utilization of agricultural inputs. In order to examine the levels of trace metals (TMs), we performed additional tests by comparing field samples using metal analysis techniques that involved ammonium acetate and EDTA, and detection by atomic absorption spectrophotometry. Our findings suggest that in soils affected by fertilizers and phytosanitary agents, the concentrations of Cu++ and Zn++ are below levels that would cause toxicity. Indeed, the levels of Cu++ are measured at 6.14 µg/g and the levels of Zn++ are measured at 4.97 µg/g. Nevertheless, the copper contents in irrigation waters from sites 01 and 02 beyond the levels that are considered dangerous. Similarly, copper levels in plants are categorized as hazardous. The findings emphasize the significance of implementing integrated pest management strategies in order to reduce the negative consequences of excessive use of agricultural inputs. Additionally, our study imposes the need to closely monitoring agricultural practices in order to mitigate environmental and public health hazards. Implementing sustainable farming practices and employing effective resource management strategies is crucial for safeguarding agricultural ecosystems and guaranteeing sustainable food production in the long run. Adopting an all-encompassing strategy is crucial for preserving the well-being of both the ecosystem and the populace.
Effect of stationary factors on the yield and chemical composition of essential oils of Tetraclinis articulata (Vahl) Masters from Sdama Chergui massif’s (Tiaret, North-West Algeria)
Authors: Bensaadi Nawel , Mhamed Maatoug , Maatoug Zakaria Zineddine , Kamel Kamel 
Published: September 2024

This paper aims to study the influence of exposure, altitude, and soil pH on the yield and chemical composition of essential oils (EOs) from the leaves of Tetraclinis articulata (Vahl) Masters, developed in the Sdama Chergui massif in northwestern Algeria. These EOs were obtained by hydrodistillation, resulting in average yields of 0.33±0.13 %, 0.29±0.07 %, 0.24±0.07 %, and 0.2±0.03 %, recorded at the south, west, north, and east exposures, respectively. Upon analyzing the obtained EOs by gas chromatography coupled with mass spectrometry (GC/MS), a total of chemical molecules grouped into 22 families were identified. The predominant compounds were Bornyl acetate (9.14 %, 7.95 %, 11.20 %, and 9.78 %), Limonene (5.03 %, 7.18 %, 5.76 %, and 5.41 %), α-Pinene (4.97 %, 5.26 %, 5.09 %, and 4.79 %), Camphor (7.53 %, 3.69 %, 3.01 %, and 5.91 %), and Borneol (5.20 %, 6.26 %, 4.93 %, and 5.11 %). Additionally, the analysis of these molecules by Factorial Analysis of Mixed Data (PCAmix) revealed that exposure, altitude, and soil pH have little effect on the yield and chemical composition of the essential oils of Tetraclinis articulata. Finally, careful attention to stationary parameters is crucial for obtaining essential oils of high quality and optimal quantity.