bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mitochondrial Respiratory Complex Biogenesis: Communication, Gene Expression and Assembly
Authors: Giegé Philippe 
Published: November 2017

AbstractThe sections in this article areIntroductionBiogenesis of Prosthetic Groups Essential for RespirationMitochondrial Respiratory Complexes AssemblyGene Expression for the Biogenesis of Mitochondrial Respiratory ComplexesMitochondria–Nucleus Cross TalkConcluding RemarksAcknowledgements
Supramolecular Structure of the Oxidative Phosphorylation System in Plants
Authors: Heinemeyer Jesco , Dudkina Natalya V. , Boekema Egbert J. , Braun Hans‐Peter 
Published: November 2017

AbstractThe sections in this article areIntroductionStructure and Function ofOXPHOSComplexesI–VSupramolecular Organization of theOXPHOSSystemConcluding RemarksAcknowledgements
The Growing Family of Plant Cyclin‐Dependent Kinases with Multiple Functions in Cellular and Developmental Regulation
Authors: Dudits Dénes , Cserháti Mátyás , Miskolczi Pál , Horváth Gábor V. 
Published: November 2017

Abstract
The sections in this article are

Introduction

Structural Diversity in the Family of Plant
CDKs

Expression Profiles of
CDK
Genes: Structures and Functions of Promoters

Diverse Functions of
CDK
Protein Complexes in Multiple Regulatory Mechanisms

Developmental Consequences of Altered
CDK
Functions

Perspectives

Acknowledgments
CDKInhibitors
Authors: Wang Hong , Zhou Yongming , Acosta Juan Antonio Torres , Fowke Larry C. 
Published: November 2017

AbstractThe sections in this article areIntroductionPlantCDKInhibitors and Sequence UniquenessExpressionInteractions with Cell Cycle Proteins andCDKInhibitionProtein Stability and ModificationsCellular LocalizationCDKInhibitors and Plant Growth and DevelopmentCell Cycle Phase TransitionsCell Cycle Exit and EndoreduplicationConcluding RemarksNotes Added at Proofing StageAcknowledgments
E2F–DP
Transcription Factors
Authors: Ramirez‐Parra Elena , del Pozo Juan Carlos , Desvoyes Bénédicte , de la Paz Sanchez María , Gutierrez Crisanto 
Published: November 2017

Abstract
The sections in this article are

E2F–DP
Transcription Factors: A Historical Perspective

Domain Organization of
E2F–DP
Proteins

Transcriptional and Post‐Translational Regulation of
E2F

E2F–DP
Target Genes

Functional Relevance of
E2F–DP
in Development

E2F
and Epigenetic Regulation of Gene Expression

Concluding Remarks: Complexity of
E2F
‐Dependent Regulation of Gene Expression

Acknowledgments
Function of the Retinoblastoma‐Related Protein in Plants
Authors: Gruissem Wilhelm 
Published: November 2017

Abstract
The sections in this article are

Introduction

Retinoblastoma Proteins and the Tumor Suppressor Concept

The Retinoblastoma Pathway is Conserved in Animals and Plants

Retinoblastoma Proteins form Complexes with
E2F
Transcription Factors to Control Entry into the Cell Cycle

G1
Restriction Point Control is Mediated by Retinoblastoma Protein Phosphorylation

Animal and Plant
DNA
Viruses Target Retinoblastoma Proteins to Induce Host
DNA
Replication

Information on Retinoblastoma Protein Function in Animal Development is Still Incomplete

Retinoblastoma Proteins may have Conserved Functions in Germline Development

Retinoblastoma Proteins Connect Stem Cell Maintenance to Cell Proliferation and Differentiation

Perturbation of
RBR
during Leaf Development Affects Cell Proliferation and Control of
DNA
Replication

Roles of Retinoblastoma Proteins in Transcription Activation and Repression

Retinoblastoma Proteins Interact with Polycomb Group Complexes in Controlling Gene Expression

Conclusion

Acknowledgments
Physiological Relevance and Molecular Control of the Endocycle in Plants
Authors: Vlieghe Kobe , Inzé Dirk , Veylder Lieven De 
Published: November 2017

AbstractThe sections in this article areIntroductionOccurrence and Physiological Role of Endoreduplication in NatureMolecular Control of the EndocycleEnvironmental and Hormonal Control of the EndocycleOutlookAcknowledgments
One‐Pot Domino Synthesis of Diarylalkynes/1,4‐Diaryl‐1,3‐diynes by [9,9‐Dimethyl‐4,5‐bis(diphenylphosphino)xanthene] (Xantphos)–Copper(I) Iodide–Palladium(II) Acetate‐Catalyzed Double Sonogashira‐Type Reaction
Authors: Qiu Shaozhong , Zhang Caiyang , Qiu Rui , Yin Guodong , Huang Jinkun 
Published: November 2017

AbstractThe low loading combination of the complex [9,9‐dimethyl‐4,5‐bis(diphenylphosphino)xanthene] (Xantphos)copper(I) iodide and simple ligand‐free palladium(II) acetate was found to be efficient for the domino synthesis of diarylalkynes by the reaction of aryl halides with trimethylsilylethynylene or bis(trimethylsilyl)acetylene in a single‐step procedure. The unsymmetrical diarylalkynes can be obtained through a one‐pot two‐step approach. The reactions of aryl bromides with 1,4‐bis(trimethylsilyl)butadiyne also furnished the corresponding 1,4‐diaryl‐1,3‐diynes in a similar fashion. This route to diarylalkynes and 1,4‐diaryl‐1,3‐diynes is complementary to previously reported synthetic procedures.magnified image
Toward Aerogel Electrodes of Superior Rate Performance in Supercapacitors through Engineered Hollow Nanoparticles of NiCo2O4
Authors: Li Jianjiang , Chen Shuai , Zhu Xiaoyi , She Xilin , Liu Tongchao , Zhang Huawei , Komarneni Sridhar , Yang Dongjiang , Yao Xiangdong 
Published: November 2017

AbstractA biomass‐templated pathway is developed for scalable synthesis of NiCo2O4@carbon aerogel electrodes for supercapacitors, where NiCo2O4 hollow nanoparticles with an average outer diameter of 30–40 nm are conjoined by graphitic carbon forming a 3D aerogel structure. This kind of NiCo2O4 aerogel structure shows large specific surface area (167.8 m2 g−1), high specific capacitance (903.2 F g−1 at a current density of 1 A g−1), outstanding rate performance (96.2% capacity retention from 1 to 10 A g−1), and excellent cycling stability (nearly without capacitance loss after 3000 cycles at 10 A g−1). The unique structure of the 3D hollow aerogel synergistically contributes to the high performance. For instance, the 3D interconnected porous structure of the aerogel is beneficial for electrolyte ion diffusion and for shortening the electron transport pathways, and thus can improve the rate performance. The conductive carbon joint greatly enhances the specific capacity, and the hollow structure prohibits the volume changes during the charge–discharge process to significantly improve the cycling stability. This work represents a giant step toward the preparation of high‐performance commercial supercapacitors.
Environment‐Adaptive Coassembly/Self‐Sorting and Stimulus‐Responsiveness Transfer Based on Cholesterol Building Blocks
Authors: Xing Pengyao , Tham Huijun Phoebe , Li Peizhou , Chen Hongzhong , Xiang Huijing , Zhao Yanli 
Published: November 2017

AbstractManipulating the property transfer in nanosystems is a challenging task since it requires switchable molecular packing such as separate aggregation (self‐sorting) or synergistic aggregation (coassembly). Herein, a unique manipulation of self‐sorting/coassembly aggregation and the observation of switchable stimulus‐responsiveness transfer in a two component self‐assembly system are reported. Two building blocks bearing the same cholesterol group give versatile topological structures in polar and nonpolar solvents. One building block (cholesterol conjugated cynanostilbene, CCS) consists of cholesterol conjugated with a cynanostilbene unit, and the other one (C10CN) is comprised of cholesterol connected with a naphthalimide group having a flexible long alkyl chain. Their assemblies including gel, crystalline plates, and vesicles are obtained. In gel and crystalline plate phases, the self‐sorting behavior dominates, while synergistic coassembly occurs in vesicle phase. Since CCS having the cyanostilbene group can respond to the light irradiation, it undergoes light‐induced chiral amplification. C10CN is thermally responsive, whereby its supramolecular chirality is inversed upon heating. In coassembled vesicles, it is interestingly observed that their responsiveness can be transferred by each other, i.e., the C10CN segment is sensitive to the light irradiation, while CCS is thermoresponsive. This unprecedented behavior of the property transfer may shine a light to the precise fabrication of smart materials.
Complicating Narratives: Defining and Deconstructing Ethical Challenges in Community Psychology
Authors: Campbell Rebecca , Morris Michael 
Published: November 2017

AbstractIn this concluding essay, we review the case studies presented in this Special Issue and examine whether community psychology has a distinctive approach to defining and resolving the core ethical canons of the Belmont Report (1979): Respect for Persons, Beneficence, and Justice. For two of these Principles—Respect for Persons and Beneficence—community psychologists elaborate upon and extend their definitions to consider their meaning in community‐based, social justice‐oriented research. The field's approach to Respect for Persons is multilevel in nature; in addition to respecting individuals and their diverse identities, we also have obligations to respect our community partnerships, the communities with whom we work, and the populations and cultures represented in our work. Similarly, for community psychologists, Beneficence is a multilevel construct that considers risks and benefits at the group, community, and cultural levels of analysis. With respect to Justice, community psychologists’ views of our ethical responsibilities are qualitatively different in meaning from the original Belmont Report and from disciplinary‐specific interpretations of this principle in ethical guidance documents from psychology, sociology, and evaluation. Our valuing of social change demands that we contribute to individual and group empowerment and liberation, and in so doing, that we avoid collusion with oppressive systems. Thus, we define our ethical responsibilities for promoting Justice as more action‐oriented than do other disciplines. The essay closes with an exploration of future directions for developing a comprehensive ethical framework for community psychology.
Engineering of a DNA Polymerase for Direct m6A Sequencing
Authors: Aschenbrenner Joos , Werner Stephan , Marchand Virginie , Adam Martina , Motorin Yuri , Helm Mark , Marx Andreas 
Published: November 2017

AbstractMethods for the detection of RNA modifications are of fundamental importance for advancing epitranscriptomics. N6‐methyladenosine (m6A) is the most abundant RNA modification in mammalian mRNA and is involved in the regulation of gene expression. Current detection techniques are laborious and rely on antibody‐based enrichment of m6A‐containing RNA prior to sequencing, since m6A modifications are generally “erased” during reverse transcription (RT). To overcome the drawbacks associated with indirect detection, we aimed to generate novel DNA polymerase variants for direct m6A sequencing. Therefore, we developed a screen to evolve an RT‐active KlenTaq DNA polymerase variant that sets a mark for N6‐methylation. We identified a mutant that exhibits increased misincorporation opposite m6A compared to unmodified A. Application of the generated DNA polymerase in next‐generation sequencing allowed the identification of m6A sites directly from the sequencing data of untreated RNA samples.
The impact of land use and land cover changes on East Asian summer monsoon precipitation using the WRF‐mosaic approach
Authors: Zhao Deming , Wu Jian 
Published: November 2017

AbstractBased on satellite‐derived land surface data, the impact of land use and land cover (LULC) changes between the 1980s and 2010s on the monsoon‐related circulation and precipitation over East Asia was explored using the Weather Research and Forecasting (WRF) regional climate model with the mosaic approach, which could consider subgrid‐scale LULC characteristics and the corresponding changes. Simulated results using the satellite‐based LULC data show that the monsoon‐related precipitation and rain belt movement could be well reproduced, whereas the precipitation was generally overestimated. In terms of the general effect of LULC changes between the 1980s and 2010s, the precipitation decreased in the north and increased in the south. Significant subregional characteristics are apparent in China, especially with respect to East Asian summer monsoon (EASM)‐related precipitation. The increased roughness induced weakened near‐surface wind speeds in the southern part of the EASM region, while the decreased roughness resulted in intensified values in the northern part. Meanwhile, the impacted EASM‐related circulation and moisture flux, which could be well explained by the LULC changes induced, influenced the pressure gradient and temperature gradient at low to middle latitudes, resulting in a weakened moisture flux from the southwest and the southeast, whereas it intensified from the South China Sea and at middle to high latitudes. In general, with weakened moisture flux at low to high latitudes, the EASM‐related rain belt's northward movement was restrained. Although the enhanced westerly currents contributed to the increased moisture flux at middle to high latitudes, the precipitation there decreased due to the stronger weakened northward moisture flux.
Cardiovascular and all-cause mortality in patients with intermittent claudication and critical limb ischaemia
Authors: van Haelst S T W , Koopman C , den Ruijter H M , Moll F L , Visseren F L , Vaartjes I , de Borst G J 
Published: November 2017

Abstract

Background
The aim of this study was to evaluate absolute mortality risks and to determine whether changes in mortality risk occurred in patients with intermittent claudication (IC) or critical limb ischaemia (CLI) in the Netherlands between 1998 and 2010.

Methods
Data for patients treated between 1998 and 2010 were obtained from Dutch nationwide registers: the Hospital Discharge Register, Population Register and Cause of Death Register. The registers were used to obtain information regarding IC and CLI hospitalizations, co-morbidities, demographic factors, and date and cause of death. The cohort was split into two time intervals for comparison: 1998–2004 (period 1) and 2005–2010 (period 2). Thirty-day mortality was excluded to eliminate per-admission complications. One- and 5-year cardiovascular and all-cause mortality rates were compared with those of a representative sample of the general Dutch population (28 494 persons) by Cox proportional hazards models.

Results
Some 47 548 patients were included, 34 078 with IC and 13 470 with CLI. In patients with IC, the age-adjusted 5-year mortality risk for cardiovascular disease decreased significantly in period 2 (14·1 per cent) compared with that in period 1 (16·1 per cent) in men only (5-year adjusted hazard ratio (HR) 0·76, 95 per cent c.i. 0·69 to 0·83; P &lt; 0·001). In patients with CLI, the cardiovascular mortality risk decreased significantly only in women, with the 5-year risk reducing from 31·2 per cent in period 1 to 29·2 per cent in period 2 (adjusted HR 0·84, 0·74 to 0·94; P = 0·004). Compared with the general population, the mortality risk in patients with IC was increased between 1·70 (1·58 to 1·83) and 3·20 (2·69 to 3·81) times, and in those with CLI the risk was increased between 2·24 (2·09 to 2·40) and 5·19 (4·30 to 6·26) times.

Conclusion
The risk of premature death in patients with IC and CLI declined significantly in the Netherlands, in a sex-specific manner, over the period from 1998 to 2010. The absolute risk of cardiovascular mortality remains high in these patients.
Mathematical Model for Numerical Simulation of Organic Compound Recovery Using Membrane Separation
Authors: Pelalak Rasool , Heidari Zahra , Soltani Hadi , Shirazian Saeed 
Published: November 2017

AbstractA novel methodology in design and simulation of membrane‐based purification of organic solvents is proposed. A solution of water and alcohol served as model feed. Mass transfer and momentum transfer equations were derived and solved numerically to obtain the process output as function of process parameters. Water was taken as penetrant throughout the simulations. The studied process was pervaporation in which a nonporous polymeric membrane is used for purification of ethanol. Feed inlet concentration and velocity were considered as process input, water outlet concentration and removal efficiency as output. The Maxwell‐Stefan mass transfer approach was applied for estimation of diffusion, the finite element approach for numerical simulation of the process. A lower feed velocity increased the water removal efficiency.
Nitrogen‐Doped Hierarchically Porous Carbon Materials with Enhanced Performance for Supercapacitor
Authors: Zeng Rong , Tang Xiannong , Huang Bingyu , Yuan Kai , Chen Yiwang 
Published: November 2017

AbstractHierarchical porous carbon (HPC) with a high specific surface area is a promising material for supercapacitors, owing to its effective ion diffusion paths and low transport resistance. Herein, a nitrogen‐doped hierarchical porous carbon (NHPC) material was successfully synthesized from a gelatin and graphene oxide composite through a combined solvation volatilization/nano‐CaCO3 template/KOH activation method. The obtained NHPC exhibits a large surface area (SBET=1091 m2 g−1) as well as a combination of electrical double layer capacitance and pseudocapacitance behavior. Benefiting from the advanced synergistic effect of the nitrogen‐doped property and the hierarchically porous structure, NHPC shows a specific capacitance of 234 F g−1 at 0.5 A g−1 in a three‐electrode system. Moreover, a supercapacitor based on NHPC exhibits an excellent cycle life (retaining>98 % after 5000 cycles) and a high energy density up to 9.43 Wh kg−1.
Single Cylindrical Nanopore Electrodes: Surface Functionalization, Unusual Voltammetry, and Size‐Exclusion Properties
Authors: Qian Yuanyuan , Zhu Jiahui , Li Yongxin 
Published: November 2017

AbstractNanopore electrodes have been proved useful tools for fundamental electrochemical research and real applications. In this work, single cylindrical gold nanopore electrodes (SCAuNEs) were fabricated through a laser‐assisted pulling and electrochemical etching method, and then characterized by scanning electron microscopy, cyclic voltammetry, and finite‐element simulations. Our results showed that the electrochemical response of the nanopore electrode corresponds to the diffusion of redox species passing through the nanopore to the underlying gold electrode: surface functionalization of the interior nanopore led to the conversion of surface charge, which could introduce pH‐dependent ion selectivity by electrostatic interaction between redox species and surface functional groups inside the nanopores. It is interesting to find the unusual voltammetric behavior at low concentrations of supporting electrolyte by using single cylindrical nanopore electrodes: the voltammetric limiting current was increased significantly with decreasing supporting electrolyte concentration, but the shift of E1/2 was dependent on the charge change of the redox species. In addition, the distinct size exclusion of two biomolecules, ferritin (ca. 12 nm) and cytochrome C (ca. 3 nm), passing through nanopores at different diameters could be obtained by monitoring the direct electrochemical signals of two biomolecules. This work is important for fundamental electrochemistry and the real applications for counting or separating biomolecules inside cylindrical nanopores.
A Superior Synthesis of Longitudinally Twisted Acenes
Authors: Clevenger Robert G. , Kumar Bharat , Menuey Elizabeth M. , Lee Gene‐Hsiang , Patterson Dustin , Kilway Kathleen V. 
Published: November 2017

AbstractSeven longitudinally twisted acenes (an anthracene, two tetracenes, three pentacenes, and a hexacene) have been synthesized by the addition of aryllithium reagents to the appropriate quinone precursors, followed by SnCl2‐mediated reduction of their diol intermediates, and several of these acenes have been crystallographically characterized. The new syntheses of the three previously reported twisted acenes, decaphenylanthracene (1), 9,10,11,20,21,22‐hexaphenyltetrabenzo[a,c,l,n]pentacene (2), and 9,10,11,12,13,14,15,16‐octaphenyldibenzo[a,c]tetracene (14), resulted in a reduction of the number of synthetic steps. As a consequence their overall yields were increased by factors of 50‐, 24‐, and 66‐fold, respectively. All of the twisted acene syntheses reported here are suitable for the synthesis of at least gram quantities of these remarkable hydrocarbon materials.
A simultaneous approach for the synthesis of multiperiod heat exchanger network using particle swarm optimization
Authors: Silva Gercio P. , Miranda Camila B. , Carvalho Esdras P. , Ravagnani Mauro A. S. S. 
Published: November 2017

AbstractIn the present paper an approach for the synthesis of multiperiod heat exchanger networks (HEN) using particle swarm optimization (PSO) is proposed, wherein all variables are optimized simultaneously. The model uses a stage‐wise superstructure in which stream splitting is considered. The HEN is synthesized for each period individually and a timesharing scheme procedure is used to integrate all the structures of different periods automatically in a unique step. The HEN is able to operate in all the considered conditions and heat transfer devices can be used for different streams in different periods. Two case studies from the literature were used to test the developed model and results for the total annual costs were better than those found in the literature.
Serum cytokine profile and clinicopathological findings in oral lichen planus, oral lichenoid lesions and stomatitis
Authors: Larsen Kristine Roen , Johansen Jeanne Duus , Reibel Jesper , Zachariae Claus , Pedersen Anne Marie Lynge 
Published: November 2017

AbstractThe objective of this study was to examine if clinical and histopathological variables in patients with oral lichen planus (OLP), oral lichenoid lesions (OLL), and generalized stomatitis display different cytokine profiles and if concomitant contact allergy influences this profile. Forty‐nine patients and 29 healthy age‐ and gender‐matched subjects were included. Demographic and clinical data immunohistochemical findings in mucosal specimens, results of contact allergy testing, and serum levels of tumor necrosis factor‐α, interferon‐γ, interleukin (IL)‐6, IL‐10, IL‐12p40, and IL‐12p70 were analyzed and compared between groups. Nineteen patients had OLP, primarily with ulcerative lesions on the buccal mucosa, 19 patients had OLL, and 11 patients had generalized stomatitis. All patients had oral symptoms, mainly stinging and burning. Nineteen patients and 10 healthy subjects had contact allergies, primarily to fragrance ingredients. Patient groups did not differ with regard to oral symptoms, clinical pattern of the lesions, or contact allergy. Serum cytokine levels did not differ between the different patient groups and were not related to histopathological findings. The patients had higher levels of IL‐6 than the healthy subjects. Interferon‐γ, IL‐12p40, and IL‐12p70 were below detection limit. Our findings indicate that OLP, OLL, and generalized stomatitis cannot be discriminated by means of the selected serum cytokines, and that the presence of concomitant contact allergy does not influence the cytokine expression.