bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metal‐Organic Framework/Layered Carbon Nitride Nano–sandwiches for Superior Asymmetric Supercapacitor
Authors: Ma Longtao , Fan Huiqing , Fu Ke , Zhao Yuwei 
Published: August 2016

AbstractThe Fe‐doped Zeolitic Imidazolate Frameworks/layered CN nano‐sandwiches (Fe‐ZIF/CN) and porous C/layered CN nano‐sandwiches (porous C/CN) were synthesized from a single Metal‐Organic Frameworks/layered CN nano‐sandwich precursor. The Fe‐ZIF/CN and porous C/CN electrode possessed high specific surface area for 1609 and 2048 m2⋅g−1 respectively and they showed high capacitance values for 1096 and 587 F⋅g−1 at the current density of 1 A g−1 under three electrode configuration. The electrochemical performance and stable potential windows of the asymmetric supercapacitors (ASCs) based on FeZIF/CN nano‐sandwiches (positive electrode) and porous C/CN (negative electrode) were further evaluated. The high energy density supercapacitor was successfully realized by the appliances (Fe‐ZIF/CN//porous C/CN), much better than those of the SSCs based on porous C/CN or Fe‐ZIF/CN electrode materials. The advanced ASCs could work within a wide potential window of 0–1.6 V, which contributed to a high specific energy density of 153 W⋅h⋅kg−1. The superior performance was ascribed to the high capacitance and the positive synergistic effects of the two electrodes. These encouraging results revealed a potential in exploiting energy storage appliance with high energy density and power density appliance for practical applications.
Tailor–made Covalent Organic‐Inorganic Polyoxometalate Hybrids: Versatile Platforms for the Elaboration of Functional Molecular Architectures
Authors: Izzet Guillaume , Volatron Florence , Proust Anna 
Published: August 2016

AbstractPost‐functionalization of organically modified polyoxometalates (POMs) is a powerful synthetic tool to devise functional building blocks for the rational elaboration of POM‐based molecular materials. In this personal account we focus on iodoaryl‐terminated POM platforms, describe reliable routes to the synthesis of covalent organic‐inorganic POM‐based hybrids and their integration into advanced molecular architectures or multi‐scale assemblies as well as their immobilization onto surfaces. Valorisation of the remarkable redox properties of POMs in the fields of artificial synthesis and molecular electronic is especially considered.
An α‐{P2W18O62}6–‐Based Supramolecular Hybrid Inorganic‐Organic Compound with Visible Light‐Driven Photocatalytic Properties
Authors: Zhu Xiaofei , Yang Yu , Jiang Ni , Li Bo , Fu Hai , Yin Zifan , Yang Jun 
Published: August 2016

Abstract The α‐[P2W18O62]6–‐based coordination polymer [Cu2(phen)3(H2O)3(P2W18O62)][Cu(phen)2(H2O)]·5H2O (1) (phen = phenanthroline), was hydrothermally synthesized and characterized by single‐crystal and powder X‐ray diffraction, IR and UV/Vis diffuse reflection spectroscopy, and elemental analysis. Structural studies reveal that compound 1 exhibits a three‐dimensional (3D) supramolecular structure based on π–π and hydrogen bonding interactions. In addition, visible light driven photocatalytic experiments of compound 1 were also studied.
Metabolic Surgery for Diabetes Treatment: Sleeve Gastrectomy or Gastric Bypass?
Authors: Lee Wei‐Jei , Chong Keong , Aung Lwin , Chen Shu‐Chun , Ser Kong‐Han , Lee Yi‐Chih 
Published: August 2016

AbstractBackgroundBariatric surgery has gained reputation for its metabolic effect and is increasingly being performed to treat type 2 diabetes mellitus (T2DM). However, there is still a gray area regarding the choice of surgical procedure according to patient characteristics due to inadequate evidences, so far. We aim to compare the efficacy of two most commonly performed bariatric/metabolic surgeries, sleeve gastrectomy (SG) and gastric bypass (GB) with regard to remission of T2DM after surgery.MethodsOutcomes of 579 (349 female and 230 male) patients who had undergone SG (109) or GB (470) for the treatment of T2DM with 1‐year follow‐up were assessed. The remission of T2DM after SG or GB surgery was evaluated in matched groups using the ABCD scoring system. The ABCD score is composed of the age, BMI, C‐peptide levels and duration of T2DM (years).ResultsThe weight loss of the SG patient at 1 year after surgery was similar to the GB patients [26.3 (1.1) vs. 32.6 (1.2) %; p = 0.258]. The mean BMI decreased from 35.7 (7.2) to 28.3 (3.7) Kg/m2 in SG patients at 1 year after surgery and decreased from 36.9 (7.2) to 26.7 (4.5) Kg/m2 in the GB patients. The mean HbA1c decreased from 8.8 to 6.1 % of the SG group and from 8.6 to 5.9 % of the GB group. Sixty‐one (56.0 %) patients of the SG group and 300 (63.8 %) of the GB group achieved complete remission of T2DM (HbA1c < 6.0 %) at 1 year after surgery without statistical difference. However, GB exhibited significantly better glycemic control than the SG surgery in groups stratified by different ABCD score. At 5 year after surgery, GB had a better remission of T2DM than SG (53.1 vs. 35.3 %; p = 0.055).ConclusionsIn conclusion, although both SG and GB are effective metabolic surgery, GB carries a higher power on T2DM remission than SG. ABCD score is useful in T2DM patient classification and selection for different procedures.
Guidelines for Perioperative Care for Liver Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations
Authors: Melloul Emmanuel , Hübner Martin , Scott Michael , Snowden Chris , Prentis James , Dejong Cornelis H. C. , Garden O. James , Farges Olivier , Kokudo Norihiro , Vauthey Jean‐Nicolas , Clavien Pierre‐Alain , Demartines Nicolas 
Published: August 2016

AbstractBackgroundEnhanced Recovery After Surgery (ERAS) is a multimodal pathway developed to overcome the deleterious effect of perioperative stress after major surgery. In colorectal surgery, ERAS pathways reduced perioperative morbidity, hospital stay and costs. Similar concept should be applied for liver surgery. This study presents the specific ERAS Society recommendations for liver surgery based on the best available evidence and on expert consensus.MethodsA systematic review was performed on ERAS for liver surgery by searching EMBASE and Medline. Five independent reviewers selected relevant articles. Quality of randomized trials was assessed according to the Jadad score and CONSORT statement. The level of evidence for each item was determined using the GRADE system. The Delphi method was used to validate the final recommendations.ResultsA total of 157 full texts were screened. Thirty‐seven articles were included in the systematic review, and 16 of the 23 standard ERAS items were studied specifically for liver surgery. Consensus was reached among experts after 3 rounds. Prophylactic nasogastric intubation and prophylactic abdominal drainage should be omitted. The use of postoperative oral laxatives and minimally invasive surgery results in a quicker bowel recovery and shorter hospital stay. Goal‐directed fluid therapy with maintenance of a low intraoperative central venous pressure induces faster recovery. Early oral intake and mobilization are recommended. There is no evidence to prefer epidural to other types of analgesia.ConclusionsThe current ERAS recommendations were elaborated based on the best available evidence and endorsed by the Delphi method. Nevertheless, prospective studies need to confirm the clinical use of the suggested protocol.
The Effect of Fluoropolymer on Wettability Alteration of Sandstone at Elevated Temperatures
Authors: Jin Jiafeng , Wang Yanling , Ren Jinheng , Nguyen Anh V. , Nguyen Tuan A. H. 
Published: August 2016

AbstractGas condensate reservoirs are generally recovered using a pressure depletion drive. Gas can condensate into the liquid phase near the wellbore region when the reservoir pressure falls below the dew point pressure, which can kill gas deliverability. Wettability alteration is an effective means of overcoming this problem; core wettability can be altered from liquid‐wet to gas‐wet to alleviate the effect of condensate accumulation near the wellbore region. To establish the effect of fluoropolymer on wettability alteration in a gas‐condensate reservoir, a gas‐wetting alteration agent was synthesized by emulsion polymerization using different molar ratios of fluorine‐containing monomers and acrylic monomers. FTIR and SEM were performed to analyze the structure of the gas‐wetting agent. Contact angle measurements were used to assess surface alteration by the Owens two‐liquid method. The effects of alteration agent concentration, salt concentration, pH and temperature on gas‐wetting alteration were also evaluated. Results showed that the best molar ratio of fluoropolymer monomer to acrylic monomers was 1:2. The egg‐like structure of the fluoropolymer latex on the core surface mainly contributes to gas‐wetting alteration. The contact angles of brine and oil can be altered from 23° and 0° to 137° and 67° by 1 wt% FP‐2 treatment, respectively. The surface free energy of the core was reduced from 67.52 to 1.66 mN/m. Moreover, the treated cores remain gas‐wetting up to 100 g L−1of salt solution, 120 °C and within the pH range of 5–7. This novel gas‐wetting alteration agent can be used to solve the problem of liquid blocking effects in gas condensate reservoirs and improve gas recovery significantly.
Innovative techniques used to plumb two 57 m height concrete buildings leaning 3.8 and 3.1 %
Authors: Maffei Carlos E. M. , Gonçalves Heloisa H. S. 
Published: August 2016

Abstract
There are about a 100 buildings visibly inclined in the city of Santos. Until the year 2000 some attempts were realized to reduce inclinations of some of those buildings without success. This paper presents the work done to plumb two buildings: Tower A and Tower B of the Condominium Nuncio Malzoni, with 57 m height that were inclined 3.8 and 3.1 %, respectively. Tower A was 2.08 m out of plumb and was brought plumb through an innovative technique in 2000. Another technique, also innovative, was accomplished to correct Tower B, 1.70 m out of plumb in 2010. Before starting the works to plumb the two buildings, a safety assessment analysis was undertaken through a complex computational analysis. The analysis showed that strengthening the structure of Tower A was urgent, since the building could be at risk of structural collapse. Due to structural differences, the Tower B was not in risk of collapse at this time. The inclination of these buildings was corrected using different techniques, which are presented in this paper.
Associations of neighborhood environment with brain imaging outcomes in the Australian Imaging, Biomarkers and Lifestyle cohort
Authors: Cerin Ester , Rainey‐Smith Stephanie R. , Ames David , Lautenschlager Nicola T. , Macaulay S. Lance , Fowler Christopher , Robertson Joanne S. , Rowe Christopher C. , Maruff Paul , Martins Ralph N. , Masters Colin L. , Ellis Kathryn A. 
Published: August 2016

Introduction“Walkable” neighborhoods offer older adults opportunities for activities that may benefit cognition‐related biological mechanisms. These have not previously been examined in this context.MethodsWe objectively assessed neighborhood walkability for participants (n = 146) from the Australian Imaging, Biomarkers and Lifestyle study with apolipoprotein E (APOE) genotype and two 18‐month‐apart brain volumetric and/or amyloid β burden assessments. Linear mixed models estimated associations of neighborhood walkability with levels and changes in brain imaging outcomes, the moderating effect of APOE ε4 status, and the extent to which associations were explained by physical activity.ResultsCross‐sectionally, neighborhood walkability was predictive of better neuroimaging outcomes except for left hippocampal volume. These associations were to a small extent explained by physical activity. APOE ε4 carriers showed slower worsening of outcomes if living in walkable neighborhoods.DiscussionThese findings indicate associations between neighborhood walkability and brain imaging measures (especially in APOE ε4 carriers) minimally attributable to physical activity.
Brachioradial Pruritus as a Harbinger of Syrinx in Chronic Spinal Cord Injury: A Case Report
Authors: Skelton Felicia , Frontera Joel E. 
Published: August 2016

AbstractThis case describes a 56‐year‐old man with known thoracic spinal cord injury undergoing evaluation for a pruritic rash on the dorsolateral aspect of his forearms with no upper extremity neuromuscular symptoms. Common diagnoses were considered and treated with little success. The diagnosis of brachioradial pruritus (BRP) was made, and evaluation for possible causes revealed a large cervicothoracic syrinx. To our knowledge, BRP has not been described previously as the presenting sign of post‐traumatic syringomelia. This patient's clinical course is delineated, as well as a brief review of BRP and its relationship to other cervical spine pathologies.Level of EvidenceV
Carboniferous deposits in the basement of the southwestern West Siberian geosyneclise (Kurgan Region)
Authors: Saraev S.V. , Baturina T.P. , Medvedev A.Ya. , Travin A.V. 
Published: August 2016

Abstract
The 40Ar/39Ar age of volcanics from the sections of core boreholes in the northern Tyumen’–Kostanai trough (Kurgan Region) has been determined. The geologic structure of the northern part of the trough has been refined. The paleogeographic environments and geodynamic settings of formation of Carboniferous deposits have been established by sedimentological, petrological, and geochemical studies of the sections. In the Visean, marine environments with maximum basin depths were predominant. In the Kachar epoch (C1v3-s), the submarine relief of the basin became more complicated; blocks of older rocks appeared in the deposits. The geochemical indicator characteristics of the volcanics—contents of HFSE (Ti, Nb, Ta, Th, and Hf)—are close to those of andesitoids of island arcs and Andean-type active continental margins, as well as present-day andesites from the Kurile–Kamchatka zone. They are an order of magnitude lower than those in similar continental-rift volcanics, among which are volcanics of the Valer’yanovka zone (according to some researchers). The contents of Ni, Co, and V are similar to those in island-arc andesites, including rocks of the Kurile–Kamchatka zone. The Ba/Ta and Ba/La ratios and the proportions of Th, Hf, and Ta in andesitoids of the Valer’yanovka and Kachar Groups are close to the indicator characteristics of island-arc and active-continental-margin volcanics. The Kachar Group siliceous rocks are similar in the Rb/Zr–Nb, Fe–Nb, and Rb–(Y + Nb) correlations to rocks of mature island arcs and active continental margins. The incompatible-element and REE patterns for the Valer’yanovka and Kachar volcanics are typical of island-arc volcanics, including rocks from the Kurile–Kamchatka zone. The indicator geochemical features and petrology of the volcanics and the sedimentologic features of the deposits testify to their formation on an Andean-type active continental margin (western margin of the Kazakhstan paleocontinent) in the Early–Middle Carboniferous.
Gold and silver minerals in low-sulfidaton ores of the Julietta deposit (northeastern Russia)
Authors: Palyanova G.A. , Savva N.E. , Zhuravkova T.V. , Kolova E.E. 
Published: August 2016

Abstract
Gold- and silver-containing pyrites of the Tikhii area at the Julietta deposit (Engteri ore cluster, Magadan Region) were studied by optical and scanning electron microscopy and electron probe microanalysis. One- or two-phase rounded microinclusions consisting of electrum (450–680‰) and/or galena or of petrovskaite and/or uytenbogaardtite, galena, and sphalerite have been found in early pyrites. Later As-pyrites (up to 2.6 wt.% As) contain multiphase xenomorphic microinclusions of acanthite, uytenbogaardtite, freibergite, argentotetrahedrite–tennantite, naumannite, petzite, selenopolybasite-selenostephanite, tellurocanfieldite, and other ore minerals localized in pores, cracks, and interstices. Pyrites that underwent hypergene alterations have rims and veinlets formed by acanthite, goethite, anglesite, plattnerite, and native silver. The presence of rounded ore mineral microinclusions and large pores in the early pyrites suggests the participation of volatiles in the mineral formation and the uptake of large amounts of impurities by pyrite under high-gradient crystallization conditions. The thermobarogeochemical studies of fluid inclusions in quartz have shown that the ore zone formed under boiling-up of hydrothermal medium-concentration NaCl solutions at 230–105 °C. The results of thermodynamic calculations evidence that Ag–Au–S–Se minerals formed under decrease in temperature and fugacity of sulfur (log10fs2 = –22 to –9) and selenium (log10fse2 = –27 to –14) and change of reducing conditions by oxidizing ones in weakly acidic to near-neutral solutions.
Assessing Groundwater Age in Confined Aquifers from the Central Pampean Plain of Cordoba, Argentina
Authors: Maldonado Marina Luciana , Blarasin Mónica Teresa , Cabrera Adriana Edith , Panarello Héctor Osvaldo , Dapeña Cristina 
Published: August 2016

AbstractIn Córdoba Province, Argentina, the population uses groundwater from confined aquifer systems (CASs) for different activities. Therefore, it is necessary to carry out comprehensive studies in order to plan more sustainable use considering that groundwater renewal times can be of several thousands of years. The objective of this research is to evaluate groundwater age in confined aquifers based on hydraulic and isotopic methods. The CASs present variable extension, are multilayered and formed by thin (4–6 m) sand-pebble lenses, and are linked to Neogene fluvial paleosystems. These layers are situated at different depths (120–400 m) and interbedded with thick clay strata. The interpretations made from 2H, 18O, and 3H results and hydraulic calculations suggest that the groundwater is old. Furthermore, an age gradient was observed that increases with depth and flow direction. The 14C ages obtained for the CASs labeled A2, C, and D were 3.6–1.1 ka BP, 10.8 ka BP, and 46.0–40.5 ka BP, respectively. These results indicate that A2 and C contain groundwater recharged during Holocene cold periods, between the Little Ice Age and the ending of the Holocene Climatic Optimum and during the last glaciation. The D CAS contains paleowater that was recharged during the Pleistocene.
Inflammation-driven malnutrition: a new screening tool predicts outcome in Crohn’s disease
Authors: Jansen Irene , Prager Matthias , Valentini Luzia , Büning Carsten 
Published: August 2016

AbstractMalnutrition is a frequent feature in Crohn’s disease (CD), affects patient outcome and must be recognised. For chronic inflammatory diseases, recent guidelines recommend the development of combined malnutrition and inflammation risk scores. We aimed to design and evaluate a new screening tool that combines both malnutrition and inflammation parameters that might help predict clinical outcome. In a prospective cohort study, we examined fifty-five patients with CD in remission (Crohn’s disease activity index (CDAI) <200) at 0 and 6 months. We assessed disease activity (CDAI, Harvey–Bradshaw index), inflammation (C-reactive protein (CRP), faecal calprotectin (FC)), malnutrition (BMI, subjective global assessment (SGA), serum albumin, handgrip strength), body composition (bioelectrical impedance analysis) and administered the newly developed ‘Malnutrition Inflammation Risk Tool’ (MIRT; containing BMI, unintentional weight loss over 3 months and CRP). All parameters were evaluated regarding their ability to predict disease outcome prospectively at 6 months. At baseline, more than one-third of patients showed elevated inflammatory markers despite clinical remission (36·4 % CRP ≥5 mg/l, 41·5 % FC ≥100 µg/g). Prevalence of malnutrition at baseline according to BMI, SGA and serum albumin was 2–16 %. At 6 months, MIRT significantly predicted outcome in numerous nutritional and clinical parameters (SGA, CD-related flares, hospitalisations and surgeries). In contrast, SGA, handgrip strength, BMI, albumin and body composition had no influence on the clinical course. The newly developed MIRT was found to reliably predict clinical outcome in CD patients. This screening tool might be used to facilitate clinical decision making, including treatment of both inflammation and malnutrition in order to prevent complications.
Aggregation of 1-year risks in life and disability insurance
Authors: Djehiche Boualem , Löfdahl Björn 
Published: August 2016

AbstractWe consider large insurance portfolios consisting of life or disability insurance policies that are assumed independent, conditional on a stochastic process representing the economic–demographic environment. Using the conditional law of large numbers, we show that when the portfolio of liabilities becomes large enough, its value on a δ-year horizon can be approximated by a functional of the environment process. Based on this representation, we derive a semi-analytical approximation of the systematic risk quantiles of the future liability value for a homogeneous portfolio when the environment is represented by a one-factor diffusion process. For the multi-factor diffusion case, we propose two different risk aggregation techniques for a portfolio consisting of large, homogeneous pools. We give numerical results comparing the resulting capital charges with the Solvency II standard formula, based on disability claims data from the Swedish insurance company Folksam.
Synergistic effects of ion transporter and MAP kinase pathway inhibitors in melanoma
Authors: Eskiocak Ugur , Ramesh Vijayashree , Gill Jennifer G. , Zhao Zhiyu , Yuan Stacy W. , Wang Meng , Vandergriff Travis , Shackleton Mark , Quintana Elsa , Frankel Arthur E. , Johnson Timothy M. , DeBerardinis Ralph J. , Morrison Sean J. 
Published: August 2016

AbstractNew therapies are required for melanoma. Here, we report that multiple cardiac glycosides, including digitoxin and digoxin, are significantly more toxic to human melanoma cells than normal human cells. This reflects on-target inhibition of the ATP1A1 Na+/K+ pump, which is highly expressed by melanoma. MEK inhibitor and/or BRAF inhibitor additively or synergistically combined with digitoxin to induce cell death, inhibiting growth of patient-derived melanomas in NSG mice and synergistically extending survival. MEK inhibitor and digitoxin do not induce cell death in human melanocytes or haematopoietic cells in NSG mice. In melanoma, MEK inhibitor reduces ERK phosphorylation, while digitoxin disrupts ion gradients, altering plasma membrane and mitochondrial membrane potentials. MEK inhibitor and digitoxin together cause intracellular acidification, mitochondrial calcium dysregulation and ATP depletion in melanoma cells but not in normal cells. The disruption of ion homoeostasis in cancer cells can thus synergize with targeted agents to promote tumour regression in vivo.
MURC deficiency in smooth muscle attenuates pulmonary hypertension
Authors: Nakanishi Naohiko , Ogata Takehiro , Naito Daisuke , Miyagawa Kotaro , Taniguchi Takuya , Hamaoka Tetsuro , Maruyama Naoki , Kasahara Takeru , Nishi Masahiro , Matoba Satoaki , Ueyama Tomomi 
Published: August 2016

AbstractEmerging evidence suggests that caveolin-1 (Cav1) is associated with pulmonary arterial hypertension. MURC (also called Cavin-4) is a member of the cavin family, which regulates caveolar formation and functions together with caveolins. Here, we show that hypoxia increasedMurcmRNA expression in the mouse lung, and thatMurc-null mice exhibited attenuation of hypoxia-induced pulmonary hypertension (PH) accompanied by reduced ROCK activity in the lung. Conditional knockout mice lackingMurcin smooth muscle also resist hypoxia-induced PH. MURC regulates the proliferation and migration of pulmonary artery smooth muscle cells (PASMCs) through Rho/ROCK signalling. Cav1 suppresses RhoA activity in PASMCs, which is reversed by MURC. MURC binds to Cav1 and inhibits the association of Cav1 with the active form of Gα13, resulting in the facilitated association of the active form of Gα13 with p115RhoGEF. These results reveal that MURC has a function in the development of PH through modulating Rho/ROCK signalling.