bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrochemical transformations and evaluation of antioxidant activity of some Schiff bases containing ferrocenyl and (thio‐)phenol, catechol fragments
Authors: Smolyaninov I.V. , Poddel'sky A.I. , Baryshnikova S.V. , Kuzmin V.V. , Korchagina E.O. , Arsenyev M.V. , Smolyaninova S.A. , Berberova N.T. 
Published: October 2017

Electrochemical transformations and antioxidant activity of some Schiff bases 1–5 containing ferrocenyl group and (thio‐)phenol, catechol fragments were investigated. Compounds under investigation are: 2‐(ferrocenylmethylene)amino)phenol (1), 2‐((ferrocenylmethylene)amino)‐4,6‐di‐tert‐butylphenol (2), 2‐((ferrocenylmethylene)amino)‐thiophenol (3), 3‐((ferrocenylmethylene)hydrazonomethyl)‐4,6‐di‐tert‐butylcatechol (4) and 2‐((3,5‐di‐tert‐butyl‐4‐hydroxybenzylidene)amino)thiophenol (5).In a case of compounds 1–3 it has shown that the sequence of electrochemical transformations leads to the products of intramolecular cyclization – 2‐ferrocenylbenzoxazole (benzothiazole). o‐Quinone formation occurs during the electrochemical oxidation of catechol‐ferrocene 4 at the first anode stage. Electrochemical oxidation of the redox‐active fragments in Schiff bases 1–4 can be achieved indirectly at a lower potential corresponding to the oxidation of ferrocenyl moiety, consequently these substances can reveal more pronounced antioxidant properties. The antioxidant activities of the compounds were evaluated using 2,2′‐diphenyl‐1‐picrylhydrazyl radical (DPPH) assay, the reaction of 2,2′‐azobis(2‐amidinopropane hydrochloride) (AAPH) induced glutathione depletion (GSH), the oxidative damage of the DNA, the process of lipid peroxidation of rat (Wistar) brain homogenates in vitro. The compounds 1–4 in the antioxidant assays show effectiveness comparable with standard antioxidants (vitamin E, Trolox) and in some parameters superior to them. In the reaction of AAPH with the glutathione compounds 2–5 have a more pronounced protective activity than Trolox. Compounds 1–5 inhibit AAPH induced oxidation damage of the DNA. The more effective inhibitors of the lipid peroxidation process in vitro are molecules containing the bulky tert‐butyl groups: 2 and 4 and Schiff base 3.
Preparations, properties, and formation mechanism of novel cellulose hydrogel membrane based on ionic liquid
Authors: Peng Huafeng , Wang Shaopeng , Xu Hongyao , Dai Guoliang 
Published: October 2017

ABSTRACTCellulose hydrogel membranes were successfully produced by casting the cellulose/1‐butyl‐3‐methylimidazolium chloride (BmimCl) solution into assembling molds, and then coagulated in water. The morphological features and mechanical properties of the prepared hydrogel membranes were characterized by a series of techniques including X‐ray diffraction measurements, scanning electron microscopy measurements, UV–visible light absorption spectrum, and tensile testing. The formation mechanism and the effects of different pre‐gelation temperature, pre‐gelation time, and coagulation batch temperature on the morphology and property of prepared cellulose hydrogel membranes were explored. The result shows that the hydrogel membrane of cellulose with excellent performance can be prepared adopting novel ionic liquid (BmimCl) as solvent through suitable process; the prepared hydrogel membranes present good mechanical properties and excellent transparency. In addition, the model of the hydrogel formation is established. It is believed that this is a promising material in the application of biomedical engineering and medical material. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45488.
Polymeric seal degradation in nuclear power plants: Determination of physical and mechanical properties
Authors: Porter Christopher P. , Bezzina James P. , Clegg Francis , Ogden Mark D. 
Published: October 2017

ABSTRACTTo assess the suitability of different materials as polymeric seals in the Nuclear Industry three commercial samples of nitrile rubber at grades BA40, BA50, and BA60 have been tested. Differential scanning calorimetry was used to find the glass transition temperature (Tg) and a Lloyds Texture Analyser 500 (TA500) was used to find the ratio of energy returned during relaxation against energy applied during compression. The mechanical properties determined from these experiments were then compared against the materials infrared spectra to infer structural characteristics. These were in turn cross‐analyzed against the materials ability to swell in a liquid solvent and absorption behavior in a gaseous solvent. From this information, a statement could be made about each material's capacity to perform as a seal. It was thus found that the high energy retention and low absorption characteristics of BA40 made this material the best choice out of those studied for use as a polymeric seal in the nuclear industry. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45814.
Supercritical CO2 deposition and foaming process for fabrication of biopolyester–ZnO bone scaffolds
Authors: Ivanovic Jasna , Rezwan Kurosch , Kroll Stephen 
Published: October 2017

ABSTRACTSubsequent supercritical CO2‐assisted deposition and foaming process followed by in situ synthesis was used to fabricate functional polylactide (PLA) and polylactide–poly(ɛ‐caprolactone) (PLA–PCL) bone scaffolds. Deposition of zinc bis(2‐thenoyltrifluoroacetonate) as a ZnO precursor onto biopolyester substrates (30 MPa; 110 °C) was followed by fast depressurization to create cellular structure. Contact time was optimized regarding the deposition yield (2 h), while PCL content in PLA was varied (1–10 wt %). Scaffolds impregnated with the precursor were treated with hydrazine alcoholic solution to obtain biopolyester–ZnO composites. Precursor synthesis and deposition onto the scaffolds was confirmed by Fourier‐transform infrared. Processed scaffolds had micron‐sized pores (d50 ∼ 20 μm). High open porosity (69–77%) and compressive strength values (2.8–8.3 MPa) corresponded to those reported for trabecular bone. PLA blending with PCL positively affected precursor deposition, crystallization rate, and compressive strength of the scaffolds. It also improved PLA surface roughness and wettability which are relevant for cell adhesion. ZnO improved compressive strength of the PLA scaffolds without significant effect on thermal stability. Analysis of structural, thermal, and mechanical properties of biopolyester–ZnO scaffolds testified a great potential of the obtained platforms as bone scaffolds. Proposed processing route is straightforward and ecofriendly, fast, easy to control, and suitable for processing of thermosensitive polymers. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45824.
Use of poly(3‐hydroxybutyrate)/niobium oxyhydroxide nanocomposites in photocatalysis: Effect of preparation methods
Authors: Heitmann Rodrigues Ana Pacheli , Rocha Italo Coura , Mottin Arthur Caron , Carlos Alves Oliveira Luiz , de Oliveira Patrício Patrícia Santiago 
Published: October 2017

ABSTRACTIn this work, nanocomposites were obtained by the dispersion of niobium oxyhydroxide into a poly(3‐hydroxybutyrate) (PHB) matrix by different preparative methods. These methods led to changes in the polymer morphology and in their photocatalytic properties. Thermal and structural properties of the nanocomposites were investigated using thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FTIR)–attenuated total reflection (ATR). Scanning electron microscopy images were analyzed in order to observe the different morphologies of nanocomposites as well as the distribution of niobium nanoparticles in the PHB matrix. The chemical interactions between the polymer and niobium nanoparticles were observed in the FTIR–ATR and thermal analyses. The results of TGA and DSC indicated an improvement in the thermal stability of the polymer and the action of inorganic nanoparticles as nucleating agents in the process of heterogeneous nucleation of PHB. The composites exhibited good catalytic activity for the removal of methylene blue dye from an aqueous medium (∼90%) during a photocatalytic process. The different morphologies of PHB/niobium oxyhydroxide composites directly influenced the catalytic activity of the material due to the difference in the dispersion of nanoparticles. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45836.
Fouling evaluation of polyethersulfone (PES)/sulfonated cation exchange resin (SCER) membrane for BSA separation
Authors: Shoparwe Noor Fazliani , Otitoju Tunmise Ayode , Ahmad Abdul Latif 
Published: October 2017

ABSTRACTIn this study, antifouling membranes were prepared through dry wet‐phase inversion method. The incorporation of electrostatistically charged group of sulfonate cation exchange resins (SCER) into polyethersulfone membrane matrix attempts to give a synergistic combination of properties for bovine serum albumin (BSA) removal. The effect of different composition of SCER into the blend membranes were characterized using scanning electron microscopy, atomic force microscopy, porosimeter, attenuated total reflectance Fourier transform infrared spectroscopy, and goniometer. All the prepared membranes were evaluated for BSA separation. The membrane resistance of all membranes decreases with increase in SCER loading. Among all membranes, P3 membrane shows a better fouling, reversible and irreversible resistance for BSA, signifying that the attached BSA on the membrane surface can be easily removed by physical cleaning. The improvement in hydrophilicity of P3 membrane was found to be the dominant factor in mitigating BSA fouling. The results demonstrated that BSA fouling could be alleviated by varying SCER concentration in the polyethersulfone matrix. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45854.
Adaptive Nonlinear Control of Reduced‐Part three‐Phase Shunt Active Power Filters
Authors: Abouelmahjoub Younes , Giri Fouad , Abouloifa Abdelmajid , Chaoui Fatima‐Zahra , Kissaoui Mohammed 
Published: October 2017

AbstractThe problem of controlling reduced‐part three‐phase shunt active power filters is addressed in the presence of nonlinear loads. The control objective is twofold: (i) compensation of the current harmonics and the reactive power absorbed by the nonlinear load in order to ensure a satisfactory power factor correction (PFC) at the grid‐filter connection point; (2) regulation of the DC bus voltage at the inverter input. The considered control problem entails several difficulties including: (1) the high dimension and strong nonlinearity of the system; (ii) the numerous state variables that are inaccessible to measurements; (iii) the system parameter uncertainty. The problem is dealt with by designing a nonlinear adaptive controller with cascade structure including two control loops. The inner‐loop regulator is designed using the Lyapunov technique to ensure the PFC objective, while the outer‐loop involves a linear PI type control law for DC bus voltage regulation. The controller also includes an adaptive observer estimating the grid voltages and impedances parameters. The resulting control performances are formally analyzed using the averaging theory. Simulation results are presented illustrating the performances and the strong robustness of the proposed control strategy.
An optimization‐based web application for synthesis and analysis of biomass‐to‐fuel strategies
Authors: Ng Rex T. L. , Patchin Sean , Wu Wenzhao , Sheth Nihar , Maravelias Christos T. 
Published: October 2017

AbstractWe develop an optimization‐based web application for assessing biomass‐to‐fuels strategies based on the Biomass Utilization Superstructure (BUS) framework. This web application allows researchers with limited knowledge of optimization to assess different technologies employed at different strategies and identify the major cost drivers. The user must only provide the necessary parameters and create an optimization run after identifying the question to be addressed and the assessment metric. The web application generates visual representations of the results once the optimal solution is obtained. Finally, we demonstrate the applicability of the web application through an example. © 2017 The Authors. Biofuels, Bioproducts and Biorefining published by Society of Chemical Industry and John Wiley & Sons, Ltd.
Characteristic component profiling and identification of different Uncaria species based on high‐performance liquid chromatography–photodiode array detection tandem ion trap and time of flight mass spectrometry coupled with rDNA ITS sequence
Authors: Zhao Bingqiang , Huang Yanjun , Chen Qiulan , Chen Qizhao , Miao Hui , Zhu Shuang , Zeng Changqing 
Published: October 2017

AbstractUncaria is a multi‐source herb and its species identification has become a bottleneck in quality control. To study the identification method of different Uncaria species herbs through HPLC–MS coupled with rDNA Internal Transcribed Spacer (rDNA ITS) sequence, both plant morphological traits and molecular identification were used to determine the species of every collected Uncaria herb. The genetic analysis of different Uncaria species was performed using their rDNA ITS sequence as a molecular marker. Meanwhile, the phylogenetic relationships of 22 samples from six Uncaria species were divided and classified clearly. By optimizing the chromatographic conditions, a practical HPLC method to differentiate various varieties of Uncaria herbs was set up based on a set of characteristic components across each species. A high‐performance liquid chromatography–photodiode array detector tandem ion trap and time of flight mass spectrometry technique combined with reference substances was utilized to derive 21 characteristic compounds containing six groups of six Uncaria species in China. Thus, this study provides a feasible method to solve the current problem of confusion in Uncaria species, and makes a significant step forward in the appropriate clinical use, in‐depth research and further utilization of different Uncaria species.
miR‐1 suppresses the proliferation and promotes the apoptosis of esophageal carcinoma cells by targeting Src
Authors: Liao Zhicong , Wang Xiaojun , Liang Hongwei , Yu Ao , ur Rehman Uzair , Fan Qian , Hu Yue , Wang Chen , Zhou Zhen , Wang Tao 
Published: October 2017

AbstractNonreceptor tyrosine kinase c‐Src, also known as Src, is a potent oncogene involved in a series of biological processes including cell growth, differentiation, and apoptosis; however, its expression pattern and function in esophageal cancer is poorly addressed. In this study, abnormal overexpression of Src protein was observed in esophageal cancer tissues, which fuelled the speculation that microRNA‐mediated posttranscriptional regulatory mechanism might be involved. Bioinformatic analyses were applied to identify miRNAs that could potentially target Src. miR‐1 was predicted and further validated as a direct repressor of Src. Moreover, we manipulated knockdown and overexpression experiment on TE‐1 and TE‐10 cells to demonstrate miR‐1 suppressed proliferation and promoted apoptosis in esophageal cancer cells by inhibiting Src. Taken together, this study underlines a negative regulatory mechanism in which miR‐1 serves as a suppressor of Src in esophageal cancer cells and may provide insights into novel therapeutic approaches for esophageal cancer.
Nationwide trends in chemotherapy use and survival of elderly patients with metastatic pancreatic cancer
Authors: van der Geest Lydia G. M. , Haj Mohammad Nadia , Besselink Marc G. H. , Lemmens Valery E. P. P. , Portielje Johanneke E. A. , van Laarhoven Hanneke W. M. , Wilmink J. (Hanneke) W. ,   the Dutch Pancreatic Cancer Group
Published: October 2017

AbstractDespite an aging population and underrepresentation of elderly patients in clinical trials, studies on elderly patients with metastatic pancreatic cancer are scarce. This study investigated the use of chemotherapy and survival in elderly patients with metastatic pancreatic cancer. From the Netherlands Cancer Registry, all 9407 patients diagnosed with primary metastatic pancreatic adenocarcinoma in 2005–2013 were selected to investigate chemotherapy use and overall survival (OS), using Kaplan–Meier and Cox proportional hazard regression analyses. Over time, chemotherapy use increased in all age groups (<70 years: from 26 to 43%, 70–74 years: 14 to 25%, 75–79 years: 5 to 13%, all P < 0.001, and ≥80 years: 2 to 3% P = 0.56). Median age of 2,180 patients who received chemotherapy was 63 years (range 21–86 years, 1.6% was ≥80 years). In chemotherapy‐treated patients, with rising age (<70, 70–74, 75–79, ≥80 years), microscopic tumor verification occurred less frequently (91‐88‐87‐77%, respectively, P = 0.009) and OS diminished (median 25‐26‐19‐16 weeks, P = 0.003). After adjustment for confounding factors, worse survival of treated patients ≥75 years persisted. Despite limited chemotherapy use in elderly age, suggestive of strong selection, elderly patients (≥75 years) who received chemotherapy for metastatic pancreatic cancer exhibited a worse survival compared to younger patients receiving chemotherapy.
Interventional cardiologists: Beware and be aware: An updated report of radiation‐induced cutaneous cancers
Authors: Eagan John T. , Jones Carolynn T. , Roubin Gary S. 
Published: October 2017

AbstractWe describe 5 years of follow‐up of a previously reported case of disabling ionizing radiation (IR)‐related cutaneous cancer in a high‐volume interventional cardiologist. This case illustrates the cycle of exposure, disease, remission, and re‐exposure that demonstrates the cause‐and‐effect relationship between radiation exposure and cutaneous cancer. Prior cautions for working in environments with radiation exposure emphasized strict adherence to the ALARA principle and called for improved radiation protection equipment. New studies stress that radiation exposure should be as near to zero as possible and place a call for research and technologies that mitigate the use of IR for all interventionists.
Corkscrew collaterals in atherosclerosis obliterans
Authors: Fujii Yuichi , Ueda Tomohiro , Uchimura Yuko , Teragawa Hiroki 
Published: October 2017

Key Clinical MessageMarked calcifications in the femoral artery obscured imaging of the artery in computed tomography (CT) and duplex ultrasonography. The presence of corkscrew collateral arteries in patients with Atherosclerosis obliterans (ASO) indicates total artery occlusion.
An 88‐year‐old patient with ADPKD: underscoring the importance of risk factor modification
Authors: Koratala Abhilash , Malpartida Freddy R , Kazory Amir 
Published: October 2017

Key Clinical MessageThe mean age of onset of end‐stage renal disease (ESRD) in autosomal dominant polycystic kidney disease (ADPKD) is between 56 and 69. Our case represents one of the oldest patients with ADPKD, whose chronic kidney disease (CKD) progression rate could be successfully reduced by optimal risk factor modification.
Asymptomatic giant retroperitoneal mass detected at a medical checkup
Authors: Takeda Tsutomu , Asaoka Daisuke , Fukumura Yuki , Watanabe Sumio 
Published: October 2017

Key Clinical MessageThe differential diagnosis of retroperitoneal mass includes liposarcoma, leiomyosarcoma, malignant fibrous histiocytoma, neurofibroma, stromal tumor, teratoma, and lymphoma. Leiomyosarcoma is rare with poorer prognosis than other soft tissue sarcomas. Soft tissue sarcoma of retroperitoneal origin often remains asymptomatic until tumor enlargement, leading to diagnosis at advanced stages.
Unique Reactivity of Dihydrosilanes under Catalysis by Supported Gold Nanoparticles: cis‐1,2‐Dehydrogenative Disilylation of Alkynes
Authors: Saridakis Iakovos , Kidonakis Marios , Stratakis Manolis 
Published: October 2017

AbstractIn contrast to monohydrosilanes (R3SiH), which in the presence of supported gold nanoparticles primarily undergo typical β‐(E)‐hydrosilylation reactions with alkynes, dihydrosilanes (R2SiH2) under catalysis of Au/TiO2 lead to cis‐1,2‐dehydrogenative disilylation reactions at room temperature with high selectivity. The disilyl adducts can be further functionalized through a one‐pot procedure, catalyzed by the same catalyst, to form substituted 2,5‐dihydro‐1,2,5‐oxadisiloles or 1,4‐disila‐2,5‐cyclohexadienes.
Electrochemical Faradaic Spectroscopy
Authors: Jadreško Dijana , Guziejewski Dariusz , Mirčeski Valentin 
Published: October 2017

AbstractFor the purpose of simplification of the electrochemical study under conditions of square‐wave voltammetry (SWV), a simplified form of potential modulation is proposed by replacing the staircase potential ramp with a constant potential. The resulting potential modulation, which could be considered as a pulse form of a chronoamperometric experiment (i. e., square‐wave chronoamperometry), is provisionally termed as electrochemical faradaic spectroscopy, considering the fact that the main tool in the kinetic analysis is the frequency of the potential pulses applied. The proposed technique is illustrated with theoretical analysis of a simple, kinetically controlled electrode reaction of a dissolved redox couple and experimentally verified with the Eu3+(aq)/Eu2+(aq) redox couple at a mercury electrode. The square‐wave chronoamperometry exhibits unique features of the response absent in both conventional SWV and chronoamperometry, widening the range of accessible electrode kinetics.
Molecular ReI Cages: Structural and Luminescent Properties
Authors: Tzeng Biing‐Chiau , Chao An , Lin Mei‐Chun , Lee Gene‐Hsiang , Kuo Ting‐Shen 
Published: October 2017

AbstractVersatile building block [{Re(CO)4}3(C3N3S3)] (1 a; C3N3S3=cyanurate trianion) reacts with linear dipyridyl ligands [i.e., pyrazine (pz), 4,4′‐bipyridine (bpy), 1,2‐bis(4‐pyridyl)ethylene (bpe), bis(4‐pyridyl)acetylene (bpa), and 1,4‐bis(pyridyl‐4‐ylethynyl)benzene (bpb)] and a tripyridyl ligand [1,3,5‐tris(4‐pyridylethynyl)benzene (tpb)] to afford a series of molecular cages [{Re(CO)3}6(L)3(C3N3S3)2] [L=pz (2), bpy (3), bpe (4), bpa (5), bpb (6)] and [{Re(CO)3}9(tpb)3(C3N3S3)3] (7) under solvothermal conditions. Various structural dimensions and motifs can be systematically tuned and obtained by using different dipyridyl and tripyridyl ligands in the reactions. The molecular cages of hexanuclear complexes 2–6 containing dipyridyl ligands feature interesting trigonal‐prismatic structures with different dimensions. Furthermore, nonanuclear complex 7 has a novel triangular‐star structure, and three benzene rings of tpb ligands form a triple‐decker arrangement with significant π⋅⋅⋅π interactions having distances of 3.490(1) and 3.528(1) Å. In addition, molecular cages 1–3 and 5–7 exhibit luminescence in the solid state, and their luminescent properties were also studied.
Everything You Always Wanted to Know about Poly‐l‐lysine Dendrigrafts (But Were Afraid to Ask)
Authors: Francoia Jean‐Patrick , Vial Laurent 
Published: October 2017

AbstractLess than a decade ago, dendrigrafts of poly‐l‐lysine (DGLs) joined the family of polycationic dendritic macromolecules. Resulting from the iterative polycondensation of an N‐carboxyanhydride in water, four generations of the dendrigraft can be obtained on a multigram scale and without chromatographic purification. DGLs share features with both dendrimers and hyperbranched polymers, but turned out to have unique biophysical and bioactive properties. The macromolecules—in their native form or functionalized—have been extensively characterized by various analytical and computational methods, and have already found numerous applications in the biomedical field, such as drug and gene delivery, biomaterials, tissue engineering, bioimaging, and biosensing. Despite a growing interest for DGLs, there is still plenty of room for further exciting developments that could result from a better exposure of these macromolecules, which is the ambition of this short review.