bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Prevalence, Profile, and Risk Factor of Patients with Ulcerative Colitis at Dr. Saiful Anwar Malang General Hospital
Authors: Mustika Syifa , Triana Nanik 
Published: April 2017

Background: The prevalence ulcerative colitis (UC) in RSCM Jakarta in 1991-1995 is 2.5%. The disease affects men and women at similar rates or slightly more common in women than in men. Age of onset follows a bimodal pattern, with a peak at 15-25 years and a smaller one at 55-65 years, although the disease can occur in people of any age. The precise etiology of UC is not well understood. UC is precipitated by a complex interaction of environmental (cigarretes, diet, non-steroidal anti-inflammatory drug/NSAID, etc), genetic, and immunoregulatory factors. This study aimed to identify the prevalence, profile and risk factor of ulcerative colitis in Dr. Saiful Anwar General Hospital Malang.Method: This is a retrospective survey analysis from medical record which was taken from 2170 patients who underwent colonoscopy in Dr. Saiful Anwar General Hospital Malang from January 2010 to December 2014. Demographic setting (sex, age), clinical features, lifestyle, diagnosis based on colonoscopy were analyzed as the variables.Results: Total patients with UC was 176 patients. The prevalence of UC during 2010-2014 was 8.2% at Dr. Saiful Anwar General Hospital. There was a similar prevalence of sex between male and female patients, in which 95 (53.4%) were male and 81 (46.6%) were female. The average age of patients with UC was 41,6 years. Most patients were presented with abdominal pain (32.90%) and weight loss (42.1%). The diagnosis based on colonoscopy were pancolitis (36%), proctosigmoiditis/proctitis (31.81%), and left-sided colitis (21.9%). The risk factors of UC identified in this study were current smoker, use of NSAIDs/traditional herbs/potion and fiber diet. Majority of ulcerative colitis study samples were non-smoker (75%), not consuming herbal treatment/NSAID (60.22%), and rarely consuming fiber (36.93%). There is a significan correlation between frequency of fiber diet and UC (r = -0.106, p = 0.000).Conclusion: The prevalence of UC was 8.2% in our hospital with men and women were equally affected, and average age was 41.6 years. Patients presented with various clinical symptoms, most are abdominal pain and weight loss. The most frequent diagnosis were pancolitis, proctosigmoiditis/proctitis, and leftside colitis. There is a significant correlation between frequency of fiber diet and UC (r = -0.106, p = 0.000).Keywords : ulcerative colitis, prevalence, profile, risk factors
Choledocholithiasis during Pregnancy: Multimodal Approach Treatment
Authors: Koncoro Hendra , Lesmana Cosmas Rinaldi , Philipi Benny 
Published: April 2017

Pregnancy is an important risk factor for growth of choledochal stones. Since choledocholithiasis encountered during pregnancy, which is also a possible cause of pancreatitis and cholangitis, may be the reason for serious morbidity and mortality both for the mother and the fetus, it should be treated. In this article, the results and reliability of endoscopic retrograde cholangiopancreatography (ERCP) application on a pregnant woman accompanied with percutaneous biliary procedures are presented. We report a case of 33-year-old woman at 19th week of gestation with cholestatic jaundice due to a common bile duct (CBD) stone managed by endoscopic retrograde cholangiopancreatography (ERCP). The patient had post ERCP pancreatitis which resolved with medical management. Percutaneous cholecystostomy was also performed to control source of infection in the gallbladder. ERCP is the first procedure that will be preferred in the treatment of choledocholithiasis in pregnancy with the right indications provided that proper precautions have been taken. Possible harmful effects of ionized radiation on fetus during fluoroscopy should be minimalized by giving in short periods and low doses.Keywords:
Diagnostic and Therapeutic Approach in Intestinal Tuberculosis
Authors: Guno Tri Hapsoro , Putra Barry A , Kamelia Telly , Makmun Dadang 
Published: April 2017

Tuberculosis was still a global health problem. Beside lung, tuberculosis also manifest in other organs, one among them is in abdominal organs. Abdominal tuberculosis was a complex disease with unspecific sign and symptoms so that its diagnostic procedure was not rarely inconclusive. We reported a 24 years old woman with chief complain of worsening abdominal pain in all region, accompanied by nausea, vomiting, bloating, and absent bowel movement. She also had a fresh bloody stool. She had an active pulmonary tuberculosis on initiation phase treatment. Physical examination suggest a bowel obstruction sign with distended abdomen and increase bowel sound. Colonoscopy procedure findings was a mass that obstruct bowel lumen in ileocaecal region, suggest for malignancy similar to computerized tomography (CT) scan result, but pathlogic result showed an active colitis without any sign of malignancy. Because of its contradiction, the second colonoscopy was performed and concluded as intestinal tuberculosis, matched with second pathologic examination. Although polymerase chain reaction (PCR) tuberculosis (TB) showed a negative result, a further clinical judgement concluded this as an intestinal tuberculosis case. Patient was finally treated as intestinal tuberculosis with first-line antituberculosis drugs and planned to have colonoscopy evaluation. After general condition was good and obstructive ileus sign was relieved, patient planned for outpatient care.
Inducing and Aggravating Factors of Gastroesophageal Reflux Symptoms
Authors: Mardhiyah Radhiyatam , Syam Ari Fahrial , Setiati Siti 
Published: April 2017

Gastroesophageal reflux disease (subsequently abbreviated as GERD) is a disease commonly found in the community. Several factors have been recognized as inducing and aggravating factors of GERD symptoms such as older age, female gender, obesity, smoking habit, alcohol consumption, certain diet and poor eating habit like eating fatty, spicy, and acid food.
Annular pancreas presenting as gastric outlet obstruction in an adult: a case report
Authors: KC Rabindra , Ghimire B , Singh YP 
Published: April 2017

Annular pancreas is a rare congenital abnormality which arises in the embryo by persistence of pancreatic tissue in the track which the ventral pancreatic bud follows in its rotation round the duodenum. A 21 years old male was admitted because of a non bilious vomiting and epigastric fullness after intake of food. Diagnosis was confirmed with contrast enhanced CT scan of the abdomen. He successfully underwent laparoscopic gastrojejunostomy with uneventful postoperative recovery. Though rare, annular pancreas should be considered as differential diagnosis in patient presenting as gastric outlet obstruction after excluding common causes.Journal of Society of Surgeons of NepalVol. 17, No. 2, 2014, Page: 35-36
Traitement des plaintes d'agression sexuelle envers les enfants dans le système de justice criminel québécois
Authors: Alonzo-Proulx Agnès , Cyr Mireille 
Published: April 2017

Les facteurs influençant le parcours des dossiers d'agression sexuelle (AS) envers les enfants dans le système de justice québécois restent méconnus. Afin de mieux cerner les variables liées à la décision des enquêteurs de fonder le dossier ou des procureurs d'autoriser la plainte, les caractéristiques de l'enfant, de l'AS, du contexte de dévoilement, de la garde, des preuves disponibles et de l'entrevue d'enquête ont été extraites de 169 entrevues et dossiers d'AS. Les résultats des régressions logistiques révèlent certains prédicteurs communs aux deux corps professionnels relativement à la décision d'accepter le dossier, soit l'âge de l'enfant et la corroboration des faits par le suspect. Chez les enquêteurs, plusieurs prédicteurs significatifs s'ajoutent : le fait que le dévoilement soit accidentel, le choix du premier confident et la fréquence des agressions. Chez les procureurs, les autres prédicteurs significatifs mis en évidence sont la protection maternelle, l'adhésion à un guide d'entrevue non suggestif de même que le nombre de faits corroborés par le témoin. Ces résultats montrent l'importance de variables liées à la preuve dans l'acceptation d'un dossier d'AS, mais soulignent également l'importance, dans le parcours judiciaire, des facteurs contextuels tels que le soutien maternel.
Effect of high protein supplementation on growth and nutrient digestibility of broiler
Authors: Hossain MA , Zulkifli I , Soleimani AF 
Published: April 2017

This study was undertaken to compare the growth performance and nutrient digestibility (energy, protein and amino acid) of broilers fed diets containing only vegetable protein (soybean) with birds that received Pro-EL as protein supplement in their diets. Day-old male broiler chicks (n=60; Cobb 500) were randomly distributed into 2 dietary treatment groups, namely control (T1) and supplemented (T2) diets, with 5 birds per replication in a CRD. Birds had a free access to iso-caloric and iso-nitrogenous starter diets in cages up to 21d. The results of FI, LW, LWG and FCR of broilers up to 21 days were poorer (P<0.01) on T2 diet than the broilers fed on T1 diet. The ileal nutrient digestibility of GE and CP was identical (P>0.05), but the majority of the AAs digestibility values were influenced (P<0.05; P<0.01) by treatments except for Gly, Thr, Cys, Val, Ile, Leu, and Phe. The digestibility of Asp, His, Arg, Ala, Pro, Ser, Glu, Tyr and Lys was impaired (P<0.05; P<0.01) in the T2 diet compared to T1 diet except for Met, which was improved (P<01) in T2 diet. It can be concluded that the negative response of broilers fed on protein supplemented diet might arise from the reduced nutrient digestibility of the diet.Bang. J. Anim. Sci. 2017. 46 (1): 44-50
Socio-geographic distribution of livestock and poultry in Bangladesh-A review
Authors: Huque KS , Khan MYA 
Published: April 2017

Bangladesh, a country of 147,570 Km2, had a total human population of 144.0 million in 2011 which is estimated as 160 million in 2015. Livestock that includes cattle, buffalo, goat and sheep and poultry such as, chicken, ducks and pigeons are important to her food and agriculture. Their total population according to Agricultural Census (2008) is 25.67, 0.54, 16.3, 1.29, 97.8, 39.43 and 7.48 million, respectively. The objective of the study was to analyse the concentration of livestock and poultry and their proportional availability to humans of different regions and their distribution to different farm categories. The average distribution range of the above animals and poultry was 19.7 to 361.7, 0.39 to 15.4, 12.4 to 359, 0.3 to 43.0, 105 to 1212, 6 to 746 and 1.5 to 190 per square kilometre, respectively; and that of human population was 86.7 to 8229/Km2. Their distribution, comparing with that of human population, that excludes the use of non-habitable land for them, shows that the average range of each farm animal and poultry available in the country was 21 to 464, 0.28 to 32.3, 8.9 to 412, 1.4 to 46.6, 72.8 to 1875, 24 to 829, and 8.9 to 198 per 1000 people, respectively. The production areas of cattle were classified into four zones (Zone A, Zone B, Zone C and Zone D), and that of each of others into three zones (Zone A, Zone B, and Zone C). They were characterized using the socioeconomic attributes of their respective zone, and the geographic distribution map of each genotype was developed and reported. The Farm household rear 85.6%, 81.0%, 75.6%, 75.8%, 75.5%, 77.5%, and 82.2%, respectively, of the total population of the above animals and poultry, respectively; and the rest is kept by the Non-Farm households. The Non-Farm and the small households together rear 73.9%, 67.1%, 82.6%, 79.9%, 82.2%, 80.2%, and 70.3%, respectively, and this shows that livestock and poultry; in addition to the production of milk, meat and eggs; support livelihood improvement of the land poor farmer in the country. However, the database of animal sourced foods (ASF) produced by them in different regions, their consumptions, wet marketing and the extent of value additions, availability of feeds and fodder, and health problems in addition to regional planning for mitigation of climate pollution of animal origin are utmost concerns for doubling of livestock and poultry production and productivity by 2030.Bang. J. Anim. Sci. 2017. 46 (1): 65-81
Überlieferungs-und Identifizierungsprobleme in den lothringischen Urkunden des Klosters Weißenburg/Wissembourg (Bas-Rhin)
Authors: Haubrichs Wolfgang 
Published: April 2017

Le "Codex traditionum" wissembourgeois nous offre un certain nombre de documents qui sont d'un grand intérêt pour l'histoire de l'époque mérovingienne et carolingienne. Plus de 80 d'entre eux datent du temps précédant l'avènement au trône du roi Pépin. Ces documents nous transmettent de nombreux NL ainsi que NP qui représentent des témoins de haute importance pour l'histoire linguistique dans ses débuts dans l'Est de la Lorraine et de l'"Alsace bossue".
Ce qui rend difficile l'exploitation scientifique de ces documents c'est le fait que quelques scribes des documents originaux - qui d'ailleurs n'ont pas été conservés - ainsi qu'un des copistes travaillant vers 860 étaient bilingues ou même de langue romane. Il est donc quelquefois assez malaisé de distinguer entre des romanismes linguistiques originaires et des romanismes causés par l'appartenance linguistique du copiste.
L'article essaie de mettre au point une méthode par laquelle ce problème devrait être résolu par la comparaison des documents qui nous ont été transmis en double exemplaire.
L'auteur discute ensuite des identifications déjà proposées dans la littérature scientifique, ou propose et explique de nouvelles identifications.
Onomástica de los judíos navarros (siglo XIV)
Authors: Cierbide Martinena Ricardo 
Published: April 2017

Les communautés juives en Navarre étaient situées surtout à Tudela, dans la vallée de l'Ebro, dont la population représentait 27,34% sur l'ensemble de la ville, le long du Chemin de Saint-Jacques, comme Pampelune, Sangûessa, Estella et Viana et aussi dans les petites villes au centre du Royaume.
Quant à l'onomastique de la société juive navarraise au Moyen Âge, on constate un triple système, l'hébreu, le roman et le basque, dont les deux premiers sont majoritaires par rapport à l'autochtone. Les prénoms masculins sont presque tous hébreux, contrairement à ceux des femmes, romans. Le maintien du système hébreu répond, sans doute, au caractère hébraïque de la communauté.
Fondamenti di una onomastica letteraria inmediata
Authors: Brendler Andrea 
Published: April 2017

Au cours de la deuxième moitié du vingtième siècle, l'onomastique littéraire a vécu un grand essor. Les nombreux articles publiés, les monographies et les encyclopédies ont en majorité une chose en commun : ils étudient la dénomination littéraire dans les textes littéraires d'une manière indirecte. Seuls quelques travaia essaient de percer les secrets de la dénomination littéraire par l 'interrogation directe des auteurs. C'est la méthode mentionnée en dernier qui pourrait apporter -en plus de l'analyse traditionnelle indirecte des textes littéraires - un nouvel éclairage à la recherche dans le domaine de la dénomination littéraire.
Le projet présenté s 'est voué à la méthode directe en interrogeant des écrivains italiens sur leur manière de procéder dans le choix des noms, la dénomination et l'utilisation des noms dans leurs œuvres.
Dans cette contribution, les stratégies les plus importantes de ce projet sont présentées.
Active Cryovolcanism on Europa?
Authors: Sparks W. B. , Schmidt B. E. , McGrath M. A. , Hand K. P. , Spencer J. R. , Cracraft M. , Deustua S. E 
Published: April 2017

Abstract
Evidence for plumes of water on Europa has previously been found using the Hubble Space Telescope using two different observing techniques. Roth et al. found line emission from the dissociation products of water. Sparks et al. found evidence for off-limb continuum absorption as Europa transited Jupiter. Here, we present a new transit observation of Europa that shows a second event at the same location as a previous plume candidate from Sparks et al., raising the possibility of a consistently active source of erupting material on Europa. This conclusion is bolstered by comparison with a nighttime thermal image from the Galileo Photopolarimeter-Radiometer that shows a thermal anomaly at the same location, within the uncertainties. The anomaly has the highest observed brightness temperature on the Europa nightside. If heat flow from a subsurface liquid water reservoir causes the thermal anomaly, its depth is ≈1.8–2 km, under simple modeling assumptions, consistent with scenarios in which a liquid water reservoir has formed within a thick ice shell. Models that favor thin regions within the ice shell that connect directly to the ocean, however, cannot be excluded, nor modifications to surface thermal inertia by subsurface activity. Alternatively, vapor deposition surrounding an active vent could increase the thermal inertia of the surface and cause the thermal anomaly. This candidate plume region may offer a promising location for an initial characterization of Europa’s internal water and ice and for seeking evidence of Europa’s habitability.
Worlds without Moons: Exomoon Constraints for Compact Planetary Systems
Authors: Kane Stephen R. 
Published: April 2017

Abstract
One of the primary surprises of exoplanet detections has been the discovery of compact planetary systems, whereby numerous planets reside within ∼0.5 au of the host star. Many of these kinds of systems have been discovered in recent years, indicating that they are a fairly common orbital architecture. Of particular interest are those systems for which the host star is low mass, thus potentially enabling one or more of the planets to lie within the habitable zone of the host star. One of the contributors to the habitability of the Earth is the presence of a substantial moon whose tidal effects can stabilize axial tilt variations and increase the rate of tidal pool formation. Here, we explore the constraints on the presence of moons for planets in compact systems based on Hill radii and Roche limit considerations. We apply these constraints to the TRAPPIST-1 system and demonstrate that most of the planets are very likely to be worlds without moons.
Comparison of Corneal Epithelial Remodeling After Femtosecond Laser–Assisted LASIK and Small Incision Lenticule Extraction (SMILE)
Authors: Ryu Ik-Hee , Kim Bong Jun , Lee Jong-Hyuck , Kim Sun Woong 
Published: April 2017

PURPOSE:
To comparatively investigate changes in epithelial thickness between myopic femtosecond laser–assisted LASIK (FS-LASIK) and small incision lenticule extraction (SMILE).

METHODS:
This study compared the topographic epithelial thickness changes in 175 myopic eyes undergoing FS-LASIK (62 eyes) or SMILE (113 eyes). Epithelial thickness was obtained using spectral-domain optical coherence tomography before surgery and 1 and 3 months after surgery. Topographic epithelial thickness obtained by automatic algorithm and thickness variability (standard deviation over 17 imaged areas) was compared between two groups. Postoperative epithelial thickness changes were correlated with treatment parameters.

RESULTS:

For FS-LASIK, the mean epithelial thickness of the center zone (2 mm in diameter), paracenter (2 to 5 mm), and mid-periphery (5 to 6 mm) increased by 3.4, 4.3, and 2.1
µ
m, respectively, at 1 month and by 4.4, 5.1, and 2.9
µ
m, respectively, at 3 months. There was an increase of 2.5, 3.9, and 4.5
µ
m, respectively, at 1 month and 3.0, 4.2, and 4.9
µ
m, respectively, at 3 months following SMILE. The epithelial thickness did not change between 1 and 3 months postoperatively following SMILE, whereas it increased further after FS-LASIK. A larger increase of epithelial thickness was observed in the central zone at 3 months following FS-LASIK than SMILE, whereas the opposite was observed in the mid-periphery. The topographic thickness variability was greater after FS-LASIK than SMILE. Corneal epithelial thickening was proportional to the amount of myopia correction after both procedures.

CONCLUSIONS:
Topographic epithelial remodeling patterns differ following FS-LASIK or SMILE. Epithelial remodeling appears to stabilize more rapidly following SMILE than FS-LASIK.

[
J Refract Surg.
2017;33(4):250–256.]
Cold tolerance of the spring-feeding larvae of the eyespotted bud moth,Spilonota ocellana(Lepidoptera: Tortricidae)
Authors: Swain J.A. , Judd G.J.R. , Cory J.S. 
Published: April 2017

AbstractIn this study, we explore the low-temperature thresholds of a pest of apple (Malus pumilaMiller; Rosaceae), the eyespotted bud moth,Spilonota ocellanaDenis and Schiffermüller (Lepidoptera: Tortricidae), in the context of spring frost.Spilonota ocellanaoverwinters as a larva, resuming activity and feeding early in the growing season when it could be vulnerable to unexpected freezing temperatures. We determined that the mean supercooling point of spring instars did not differ for larvae within or outside leaf shelters and ranged from −9.1±0.2 °C for fourth instars, to −7.9±0.2 °C for sixth instars. Larval weight increased with instar and was positively related to the supercooling point. As some insects are freeze tolerant and able to recover from freezing, we also exposed larvae to brief freeze events between −4.5 °C and −9.5 °C and found that the median lower lethal temperature, was −7.3±0.4 °C across all instars; indicating thatS. ocellanaspring instars are susceptible to freezing temperatures above their supercooling point. These low-temperature thresholds suggest that in the spring, S. ocellanalarvae are chill susceptible, and a hard frost (<−7 °C) would be necessary to cause significant larval mortality.
Antibody Distance from the Cell Membrane Regulates Antibody Effector Mechanisms
Authors: Cleary Kirstie L. S. , Chan H. T. Claude , James Sonja , Glennie Martin J. , Cragg Mark S. 
Published: April 2017

Abstract
Immunotherapy using mAbs, such as rituximab, is an established means of treating hematological malignancies. Abs can elicit a number of mechanisms to delete target cells, including complement-dependent cytotoxicity, Ab-dependent cellular cytotoxicity, and Ab-dependent cellular phagocytosis. The inherent properties of the target molecule help to define which of these mechanisms are more important for efficacy. However, it is often unclear why mAb binding to different epitopes within the same target elicits different levels of therapeutic activity. To specifically address whether distance from the target cell membrane influences the aforementioned effector mechanisms, a panel of fusion proteins consisting of a CD20 or CD52 epitope attached to various CD137 scaffold molecules was generated. The CD137 scaffold was modified through the removal or addition of cysteine-rich extracellular domains to produce a panel of chimeric molecules that held the target epitope at different distances along the protein. It was shown that complement-dependent cytotoxicity and Ab-dependent cellular cytotoxicity favored a membrane-proximal epitope, whereas Ab-dependent cellular phagocytosis favored an epitope positioned further away. These findings were confirmed using reagents targeting the membrane-proximal or -distal domains of CD137 itself before investigating these properties in vivo, where a clear difference in the splenic clearance of transfected tumor cells was observed. Together, this work demonstrates how altering the position of the Ab epitope is able to change the effector mechanisms engaged and facilitates the selection of mAbs designed to delete target cells through specific effector mechanisms and provide more effective therapeutic agents.