bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative evaluation of lithium estimation for samples collected in different tubes and its stability on storage
Authors: Ikkurthi Saidaiah , Balachander Srinivas , Goyal Bela , Mir Altaf Ahmad , Chakrabarti Subho , Pal Arnab 
Published: January 2018

Abstract
PURPOSE: Lithium (Li) is a well-established drug for the treatment of bipolar affective disorders. Li as a drug is known to possess a narrow therapeutic index. Thus, regular monitoring of blood Li in patients receiving Li therapy is essential. Plain tubes with clot activator are known to interfere with Li estimation. The current study was planned to compare Li estimation in sera from vacutainers with clot activator, and plasma from sodium heparinized vacutainers with that of Li estimation in sera from glass vials. The time-dependant stability of Li estimation on storage at 2°C–8°C for 48 h in these three set of tubes was also evaluated.
MATERIALS AND METHODS: Blood from the patients on Li therapy (n = 100) was collected in 3 different collection tubes: plain vacutainer with clot activator (S), Sodium heparinized vacutainer (P) and Glass vial (G) and was analyzed by ion selective electrode (ISE) analyzer for Li levels. Secondary aliquots were also taken from each type of collection tube and stored at 2°C–8°C. Time-dependant stability of Li estimation was checked at 12 h, 24 h, and 48 h. ANOVA followed by Tukey's posttest was performed to calculate statistical significance taking glass vial as reference collection tube. Bland–Altman plots were plotted to compare between three collection tubes at baseline. Stability on storage was defined when >95% of the samples were within allowable error limit for that time point taking baseline levels as reference.
RESULTS: A mean bias of 0.18 mmol/L and mean percentage bias of 19.9% in Li levels was observed between serum from (S) than serum from (G). This difference was found to be statistically significant. However, statistically nonsignificant mean bias of 0.02 mmol/L and mean percentage bias of 3.34% in Li levels was observed between plasma from (P) and serum from (G). Time-dependant stability was observed more in glass vials as compared to vacutainers with clot activator or sodium heparin.
CONCLUSION: Serum from glass vial should be the preferred method for blood collection to determine Li levels.
Decreasing trend of seroprevalence of hepatic amoebiasis in tertiary care hospital of North India: 2010–2015
Authors: Agrawal Sonu , Verma Nishant , Perumalla Sowjanya , Mirdha Bijay Ranjan 
Published: January 2018

Abstract
BACKGROUND: Globally, amoebic liver abscess, a common extraintestinal complication of intestinal amoebiasis. Diagnosis of hepatic amoebiasis is based on the detection of anti-Entamoeba histolytica immunoglobulin G (IgG) antibody using enzyme-linked immunosorbent assay (ELISA), because of its technique's relatively higher sensitivity and specificity (90%).
AIM: The aim of the present study was to determine the seroprevalence of hepatic amoebiasis in a referral tertiary care hospital in North India.
MATERIALS AND METHODS: The blood samples were tested specifically for anti-E. histolytica IgG antibody using commercially available ELISA kit (RIDASCREEN® E. histolytica IgG [K1721] kit).
RESULTS: A total of 879 patients (n = 879) were evaluated, of which 78.49% (690/879) were positive for anti-E. histolytica IgG antibody. The seroprevalence rates showed a declining trend from 2010 to 2015 with rates falling from 91.4% to 66.7%. He present a study showed the decreasing trend of seroprevalence of hepatic amoebiasis from 2010 to 2015.
CONCLUSIONS: This decrease may be attributed to several factors such as increase in awareness, improved hygienic practices, use of safe drinking water, better socioeconomic condition, and perhaps early treatment sought for intestinal amoebiasis.
Internal quality control of blood products: An experience from a tertiary care hospital blood bank from Southern Pakistan
Authors: Sultan Sadia , Zaheer Hasan Abbas , Waheed Usman , Baig Mohammad Amjad , Rehan Asma , Irfan Syed Mohammed 
Published: January 2018

Abstract
INTRODUCTION: Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients. The main objective of this study is to analyze the IQC of blood products as an indicator of our blood bank performance.
METHODS: An observational cross-sectional study was conducted at the blood bank of Liaquat National Hospital and Medical College, from January 2014 to December 2015. A total of 100 units of each blood components were arbitrarily chosen during the study. Packed red cell units were evaluated for hematocrit (HCT); random platelet concentrates were evaluated for pH, yield, and culture; fresh frozen plasma (FFP) and cryoprecipitate (CP) were evaluated for unit volume, factor VIII, and fibrinogen concentrations.
RESULTS: A total of 400 units were tested for IQC. The mean HCT of packed red cells was 69.5 ± 7.24, and in 98% units, it met the standard (<80% of HCT). The mean platelet yield was 8.8 ± 3.40 × 109/L and pH was ≥6.2 in 98% bags; cultures were negative in 97% of units tested. Mean factor VIII and fibrinogen levels were found to be 84.24 ± 15.01 and 247.17 ± 49.69 for FFP, respectively. For CP, mean factor VIII and fibrinogen level were found to be 178.75 ± 86.30 and 420.7 ± 75.32, respectively.
CONCLUSION: The IQC of blood products at our blood bank is in overall compliance and met recommended international standards. Implementation of standard operating procedures, accomplishment of standard guidelines, proper documentation with regular audit, and staff competencies can improve the quality performance of the transfusion services.
Clinical Study of various Nail Disorders presenting to Dermatology Outpatient Department
Authors: Rathore Praveen K , Goyal Sapna , Kumar Anuj , Garg Parul 
Published: January 2018

ABSTRACT

Aims and objectives
To study the clinical spectrum of nail disorders including congenital, developmental, infectious, neoplastic, degenerative, dermatological, and systemic diseases affecting the nail unit.

Materials and methods
A total of 100 consecutive cases of nail disorders reporting to the dermatology outpatient department in Rohilkhand Medical College & Hospital were examined. Complete dermatological, systemic, hematological examinations, Gram staining, scraping for fungus, nail clipping for potassium hydroxide mount, fungal culture, biopsy from nail bed were undertaken in doubtful cases.

Observations and results
Among 100 cases, the most common was onychomycosis — 28 cases, followed by nail psoriasis — 13 cases, pitting — 10 cases, paronychia — 9 cases, trachyonychia — 5 cases, onycholysis — 4 cases, clubbing — 3 cases, koilonychia — 3 cases, ingrow toenail — 3 cases, pterygium — 3 cases, onychogryphosis — 2 cases, subungual wart — 2 cases, half and half nail — 2 cases, anonychia — 2 cases, longitudinal grooves — 2 cases, clubbing with resorption of fingers — 2 cases, onychomadesis — 1 case, nail discoloration — 1 case, melanonychia — 1 case, pachyonychia congenita — 1 case, beau's line — 1 case, racket nail — 1 case, transverse groove — 1 case.

Conclusion
Among examined cases, onychomycosis was most common followed by another nail disorders.

How to cite this article
Garg P, Kumar A, Rathore PK, Goyal S. Clinical Study of various Nail Disorders presenting to Dermatology Outpatient Department. Int J Adv Integ Med Sci 2017;2(3):125-129.
Assessment of Depression and Anxiety in Chronic Obstructive Pulmonary Disease Patients attending Pulmonary Medicine Department of Rohilkhand Medical College & Hospital, Bareilly, Uttar Pradesh, India
Authors: Sharma Preeti , Kumar Abhishek , Jaiswal Arpit , Sharma Chandra S , Rathi Harsh , Arya Viddur 
Published: January 2018

ABSTRACT

Introduction
Chronic disease like chronic obstructive pulmonary disease (COPD) is associated with various comorbidities. Anxiety and depression are among the common comorbidities and have significant impact on socioeconomic status of the person as well as the course of disease. In our study, we screened COPD patients attending the outpatient department (OPD) of pulmonary medicine for anxiety and depression, using different scales that include questionnaires. About 46.2 and 34.6% cases were found to have depression and anxiety respectively, among all COPD patients (n = 156). Incidence of anxiety and depression was directly proportional to severity of disease. Age, gender, locality, educational, marital, and socioeconomic statuses are some factors that play important roles in the development of these psychiatric comorbidities. Hence, mental assessment of COPD patients should be mandatory with every visit to the OPD.

How to cite this article
Jaiswal A, Kumar A, Rathi H, Sharma CS, Sharma P, Arya V. Assessment of Depression and Anxiety in Chronic Obstructive Pulmonary Disease Patients attending Pulmonary Medicine Department of Rohilkhand Medical College & Hospital, Bareilly, Uttar Pradesh, India. Int J Adv Integ Med Sci 2017;2(3):137-139.
Inorganic carbon and water masses in the Irminger Sea since 1991
Authors: Fröb Friederike , Olsen Are , Pérez Fiz F. , García-Ibáñez Maribel I. , Jeansson Emil , Omar Abdirahman , Lauvset Siv K. 
Published: January 2018

Abstract. The subpolar region in the North Atlantic is a major sink for anthropogenic carbon. While the storage rates
show large interannual variability related to atmospheric forcing, less is
known about variability in the natural dissolved inorganic carbon (DIC) and
the combined impact of variations in the two components on the total DIC
inventories. Here, data from 15 cruises in the Irminger Sea covering the
24-year period between 1991 and 2015 were used to determine changes in total
DIC and its natural and anthropogenic components. Based on the results of an
extended optimum multiparameter analysis (eOMP), the inventory changes are
discussed in relation to the distribution and evolution of the main water
masses. The inventory of DIC increased by 1.43 ± 0.17 mol m−2 yr−1 over the period, mainly driven by the
increase in anthropogenic carbon (1.84 ± 0.16 mol m−2 yr−1) but
partially offset by a loss of natural DIC
(−0.57 ± 0.22 mol m−2 yr−1). Changes in the carbon storage rate
can be driven by concentration changes in the water column, for example due
to the ageing of water masses, or by changes in the distribution of water masses
with different concentrations either by local formation or advection. A
decomposition of the trends into their main drivers showed that variations in
natural DIC inventories are mainly driven by changes in the layer thickness
of the main water masses, while anthropogenic carbon is most affected by
concentration changes. The storage rates of anthropogenic carbon are
sensitive to data selection, while changes in DIC inventory show a robust
signal on short timescales associated with the strength of convection.
EFICIÊNCIA AGRONÔMICA DA CULTURA DA SOJA (Glycine max (L.) Merril) SUBMETIDA A COINOCULAÇÃO.
Authors: Sordi André , Scheneider Fernando , Panizzon Luis Carlos , Lajús Cristiano Reschke , Cericato Alceu , Klein Claudia 
Published: January 2018

A utilização de coinoculante é uma prática de baixo custo para culturas fixadoras de nitrogênio. O presente trabalho teve por objetivo avaliar o efeito da coinoculação na cultura da soja, visando aumentar o rendimento, aplicando os inoculantes nas sementes em sistema de semeadura direta, no município de Guaraciaba - SC. O delineamento experimental foi conduzido em blocos casualizados, arranjados em faixas, com 07 tratamentos, constituídos da combinação de inoculante padrão e Azospirillum, sendo: Não inoculado; Bradyrhizobium 100mL 50kg-1 de sementes; Azospirillum 100mL 50kg-1 de sementes; Azospirillum 50mL + Bradyrhizobium 50mL 50kg-1 de sementes; Azospirillum 100mL + Bradyrhizobium 100mL 50kg-1 de sementes; Azospirillum 150mL + Bradyrhizobium 150mL 50kg-1 de sementes; Azospirillum 200mL + Bradyrhizobium 200mL 50kg-1 de sementes. Foram avaliados rendimento de grãos, massa de mil sementes, índice SPAD (Soil Plant Analysis Development), teor de nitrogênio na folha e a eficiência econômica. O rendimento de grãos e massa de mil sementes foram submetidos à análise de variância pelo teste F e as diferenças entre médias foram comparadas pelo teste de Tukey (P≤0,05). A cultura da soja submetida à coinoculação obteve maior rendimento na dosagem de 400 mL 50kg-1 de sementes, chegando a elevar em até 13,3% em relação a não inoculada, tendo assim diferença estatística. Não houve diferença significativa para a variável massa de mil grãos. A eficiência econômica, apresentou margem líquida positiva, em todas as doses de inoculantes testadas, comparativamente a não inoculada, sendo que a mais expressiva foi também na maior dosagem de coinoculante de 400 mL 50kg-1 de sementes (Azospirillum 200mL + Bradyrhizobium 200mL 50kg-1 de sementes). A análise de regressão revelou correlação entre as doses de coinoculante e os teores de N e o índice de SPAD principalmente em R2, no entanto, observa-se a necessidade de mais estudos para calibração do clorofilômetro na cultura da soja.
Economic productivity loss due to breast cancer in Norway – a case control study using the human capital approach
Authors: Dahl Fredrik A , Šaltytė Benth Jūratė , Aas Eline , Lurås Hilde 
Published: January 2018

We estimate the productivity loss attributable to breast cancer in Norway, using a human capital approach where the value to the national economy of subjects’ labor is estimated through their income. Since the approach takes the viewpoint of the society, it includes reduced labor due to mortality as well as reduction among survivors. A case-control design was used. The Norwegian Cancer Registry identified 2,010 patients aged 45-54 years, with breast cancer as their first life-long malignancy diagnosis in 1992-1996. Statistics Norway matched these with random controls of the same age, marital status and municipality residency, and provided data on pension qualifying income until the year 2005, inflation adjusted to 2012 €. The effect of the cancer diagnosis on income throughout the follow-up period was estimated as the difference between the cases’ and controls’ income, corrected for systematic differences between cases and controls before the diagnosis. A quadratic curve approximation was used to estimate effects after the 13 years follow-up period, and a bootstrap resampling approach was applied to compute confidence intervals (CI). Regression modeling was used to estimate life-long productivity loss as a function of age at diagnosis. This was combined with the current Norwegian age distribution of breast cancer incidence, to estimate the national productivity loss due to breast cancer. For our cohort, the 13-years productivity loss attributable to the diagnosis was estimated to 102,600 € per case, with 95% CI (88,500, 116,700). The life-long estimate was 119,200 €, CI (95,400, 155,600). The annual national productivity loss was estimated to 179,900,000 €, or 58,200 € per case. For those aged < 65 at diagnosis, the estimate was 94,300 € per case. The estimated life-long productivity loss depends heavily on the age at diagnosis. The results can be used for evaluating the societal economic benefit from breast cancer prevention programs. Published: Online December 2017. In print December 2017.
Experiências educativas com narrativa fílmica: problematizando o cinema em sala de aula
Authors: Freisleben Jéssica Maria , Corrêa Milena Regina Duarte 
Published: January 2018

Este trabalho intenta apresentar experiências educativas de problematização de uma narrativa fílmica no ambiente escolar. Configura-se como relato de experiência docente no âmbito da escola pública, com jovens estudantes do 8º ano do Ensino Fundamental, com idade entre 14 e 16 anos. A escola é integrante da rede municipal de educação, da cidade de Santa Maria/RS. A experiência é focada nas questões disparadas pelo encontro com o filme “A Invenção de Hugo Cabret” assistido com duas turmas, nelas buscou-se possibilidades de inventar inusitadas tessituras e relançar outras problematizações com e para os filmes. A perspectiva narrativa foi escolhida para integrar essa investigação, visto que ao narrarmos fazemos escolhas já que narramos de acordo com nossa visão e entendimento de mundo. Enviado em: 06 de junho de 2017.Aprovado em: 13 de julho de 2017.
Imagem fílmica: um encontro que nos convoca a pensar
Authors: Cardonetti Vivien Kelling , Oliveira Marilda Oliveira de 
Published: January 2018

Este texto intenciona movimentar diferentes fluxos de pensamentos a partir das inquietações que dispararam de um encontro fílmico. Em vista das experiências em assistir ao filme ‘A Árvore da Vida’ (2011) em dois cenários distintos (em um contexto distante do âmbito da academia e o outro com os acadêmicos da Graduação em Artes Visuais da Universidade Federal de Santa Maria - RS), buscou-se explorar o atravessamento da imagem fílmica selecionada, das narrativas produzidas nos diários pelos envolvidos na investigação e dos conceitos operados na pesquisa, especialmente os conceitos de imagem-movimento e imagem-tempo (DELEUZE, 1983; 1990; 2010). As problematizações suscitadas a partir deste cruzamento tiveram a potência de afetar e inquietar, possibilitando a produção de diferentes arranjos e tessituras em relação às imagens fílmicas e à experiência educativa. Enviado em: 29 de junho de 2017.Aprovado em: 13 de julho de 2017.
Caminhos de uma pesquisa: a costurografia como outra escrita acadêmica
Authors: Ribetto Anelice , Nascimento Rejane 
Published: January 2018

Este trabalho intenta trazer uma conversa entre uma estudante e uma professora de um programa de Pós-Graduação em Educação e a experiência de uma pesquisa. Apostando em outros contornos metodológicos acontece um deslocamento da produção conceitual da própria escrita. Escrever como costurar. No percurso da pesquisa, a estudante, começa a problematizar a escrita acadêmica como empreitada coletiva, como aposta política, ética e estética. Neste percurso cartografado, a costurografia como manualidade, como um dispositivo. Uma escrita feita à mão, com linhas, agulha e retalhos de jeans. A partir de restos, a costurografia se compõe no tecido e também em outras superfícies possíveis. Feita no jeans e no papel. Gestos mínimos, ínfimos. Uma escrita experimentação. Enviado em: 09 de novembro de 2017.Aprovado em: 30 de novembro de 2017.
Sex differences in the use of social information emerge under conditions of risk
Authors: Brand Charlotte O. , Brown Gillian R. , Cross Catharine P. 
Published: January 2018

Social learning provides an effective route to gaining up-to-date information, particularly when information is costly to obtain asocially. Theoretical work predicts that the willingness to switch between using asocial and social sources of information will vary between individuals according to their risk tolerance. We tested the prediction that, where there are sex differences in risk tolerance, altering the variance of the payoffs of using asocial and social information differentially influences the probability of social information use by sex. In a computer-based task that involved building a virtual spaceship, men and women (N = 88) were given the option of using either asocial or social sources of information to improve their performance. When the asocial option was risky (i.e., the participant’s score could markedly increase or decrease) and the social option was safe (i.e., their score could slightly increase or remain the same), women, but not men, were more likely to use the social option than the asocial option. In all other conditions, both women and men preferentially used the asocial option to a similar degree. We therefore found both a sex difference in risk aversion and a sex difference in the preference for social information when relying on asocial information was risky, consistent with the hypothesis that levels of risk-aversion influence the use of social information.
Adaptation of Nussbaum's Capabilities Framework to Community Mental Health: A Consumer‐Based Capabilities Measure
Authors: Sacchetto Beatrice , Ornelas José , Calheiros Maria Manuela , Shinn Marybeth 
Published: January 2018

AbstractThe capabilities approach provides a rich evaluative framework to guide transformative change in the community mental health system. This study reports the content and construct validity and psychometric properties of a contextualized measure of the extent to which mental health programs foster achieved capabilities. The Achieved Capabilities Questionnaire for Community Mental Health (ACQ‐CMH), adapted from Nussbaum's capabilities framework, was developed previously with consumer collaboration. Content validity was assessed through a collaborative process, involving a panel of eight consumers, staff members, and senior researchers. The resulting shorter version (ACQ‐CMH‐98) was completed by 332 community mental health consumers sampled throughout Portugal. Factor (PCA) analysis, internal consistency reliability, and test–retest reliability over 2 weeks (N = 33) showed good psychometric properties. The resulting six‐factor structure with 48 items explains 48.88% of the total variance (KMO = 0.89; Bartlett p = .00). Internal consistency of the obtained dimensions ranges from .91 to .76. Associations of the measure with recovery, quality of life, and psychological distress scales add further evidence of construct validity. The adaptation of Nussbaum's framework stressed specific components that may enhance understanding and change within the community mental health system.
Auf dem Weg zur Smart Factory: modulare, intelligente Konzepte für die Produktion von Spezialchemikalien der Zukunft
Authors: Reitze Arnulf , Jürgensmeyer Nikolas , Lier Stefan , Kohnke Marco , Riese Julia , Grünewald Marcus 
Published: January 2018

AbstractDie Digitalisierung und Flexibilisierung von Produktionsprozessen bieten in der Spezialchemie die Chance, auf marktseitige Herausforderungen adäquat zu reagieren. Kürzer werdende Produktlebenszyklen, zunehmende Produktindividualisierung und die daraus resultierende Volatilität der Märkte stellen neue Anforderungen an Anlagenbetreiber. Neuartige Konzepte wie modulare Produktionsanlagen sowie Technologieentwicklungen im Rahmen der Industrie 4.0 können dabei helfen, die Smart Factory in der Spezialchemie umzusetzen. Im Folgenden werden die für diesen Wandel notwendigen Konzepte vorgestellt.
Alkoxy Tetrazine Substitution at a Boron Center: A Strategy for Synthesizing Highly Fluorogenic Hydrophilic Probes
Authors: Wu Min , Wu Xiaoai , Wang Yayue , Gu Lei , You Jiao , Wu Haoxing , Feng Ping 
Published: January 2018

AbstractStrongly fluorogenic boron dipyrromethene (BODIPY)–tetrazine probes have been obtained by introducing an alkoxy tetrazine fragment at the boron center. The fluorescence signal from these probes strongly increases by up to 225‐fold after reaction with bioorthogonal coupling partners, and the hydrophilicity of probes is improved, such that they are suitable for live‐cell imaging.