bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful Use of Topical Voriconazole 1% Alone as First-Line Antifungal Therapy Against Candida albicans Keratitis
Authors: Al-Badriyeh Daoud , Leung Lok , Davies Geoffrey E , Stewart Kay , Kong David 
Published: September 2024

Objective: To report the successful use of topical voriconazole 1% given alone as primary therapy against a case of Candida albicans keratitis. Case Summary: A 48-year-old previously well man presented to the emergency department with pain and foreign body sensation in the left eye following exposure to dust while driving a forklift He wore weekly disposable soft contact lenses. Anterior stromal scar and dense infiltrate were detected in the left eye. The anterior chamber remained deep, with flare and copious white cells. Intraocular pressure was 12 mm Hg and visual acuity was 20/200. The epithelial defect persisted, with progressive thinning despite topical fluorometholone and ofloxacin 0.3% therapy for 2 days. Microbiology testing revealed C. albicans as the affecting pathogen. Hourly administration of voriconazole 1% eye drops was initiated as antifungal therapy. The corneal infiltrate began to resolve and the epithelial defect decreased in size within 2 days. Visual acuity improved to 20/120. After 4 days of voriconazole use, the epithelial defect was completely healed and visual acuity was 20/30 in the affected eye. No fungi were isolated from a second eye scrape. Discussion: Topical voriconazole as salvage monotherapy to manage fungal keratitis has been previously reported. It can be argued, however, that the primary therapy has facilitated the positive response to subsequent topical voriconazole. To date, there has been no solid evidence to suggest that topical voriconazole is effective when used as primary therapy. The current report provides evidence of topical voriconazole demonstrating clinical success when used as first-line therapy to treat C. albicans keratitis. The use of topical voriconazole can reduce the costs, toxicity, and drug interactions associated with common antifungal therapies. Conclusions: Topical voriconazole 1% eye drops administered alone demonstrated success as first-line therapy against the most common fungal keratitis, C. albicans keratitis.
Treatment of Recurrent Stenotrophomonas maltophilia Ventilator-Associated Pneumonia with Doxycycline and Aerosolized Colistin
Authors: Wood G Christopher , Underwood Elizabeth L , Croce Martin A , Swanson Joseph M , Fabian Timothy C 
Published: September 2024

Objective: To report a case of recurrent Stenotrophomonas maltophilia ventilator-associated pneumonia (VAP) that was successfully treated with doxycycline and aerosolized colistin. Case Summary: A 28-year-old male was admitted with a severe head injury and required mechanical ventilation. The patient developed S. maltophilia VAP on hospital day 17, which was cured after 7 days of treatment with high-dose intravenous trimethoprim/sulfamethoxazole (TMP/SMX). However, on day 34, the patient developed recurrent S. maltophilia VAP that did not respond clinically or demonstrate eradication on follow-up culture after 10 days of TMP/SMX. At that time, TMP/SMX was discontinued and treatment was initiated with intravenous doxycycline and aerosolized colistin. The VAP episode was cured after 14 days of treatment with doxycycline/aerosolized colistin. Discussion: S. maltophilia is an emerging cause of VAP in some centers. This organism is associated with high mortality rates and has few treatment options because it is intrinsically resistant to most drug classes. Recent data suggest that doxycycline and aerosolized colistin each are effective in treatment of other multidrug-resistant organisms, such as Pseudomonas aeruginosa and Acinetobacter baumannii. However, this is the first report describing the use of this antibiotic regimen for S. maltophilia. High-dose TMP/SMX is considered to be the drug of choice primarily based on excellent in vitro activity. Few data exist on how to treat patients who fail therapy with TMP/SMX or cannot receive that drug because of resistance, allergy, or adverse events. Thus, it is important to report alternative methods for treating this infection. Conclusions: The positive clinical response to doxycycline and aerosolized colistin seen in the patient described here suggests that this combination may be an alternative treatment in patients who fail initial treatment or cannot receive standard therapies.
Literacy Promotion: An Essential Component of Primary Care Pediatric Practice: Policy Statement
Authors: Klass Perri , Miller-Fitzwater Anna , High Pamela C. ,   COUNCIL ON EARLY CHILDHOOD, Anderson Ashaunta T. , Dunlap Marny , Hutton John S. , Mendelsohn Alan L. , Navsaria Dipesh , Anyigbo Chidiogo Uzoatu , Burghardt Lindsey , Glusman Mariana , Guevara James P. , Hashikawa Andrew Nobuhide , Loria Hilda Marie , Miller-Fitzwater Anna , Nelson Bergen Ballard , Garro Nicole , Gomez Maritza , Lieser Dina Joy , Parlakian Rebecca , Clark Keisha , Smiley Stephanie , Sells Jill , Alderman Sherri , Bauer Nerissa , Peacock Georgina , Shriver Amy , Takagishi Jennifer , Vanderbilt Douglas , Garagozlo Katiana , Gadhia Ami , Lee Michelle , Recio Lucy 
Published: September 2024

Reading together often with infants and young children strengthens their relationships with parents and caregivers at a critical time in child development, stimulating brain circuitry and early attachment. A positive parenting practice, shared reading helps build the foundation for healthy social-emotional, cognitive, language, and literacy development, setting the stage for school readiness and providing enduring benefits across the life course.
Pediatric physicians and advanced care providers have a unique opportunity to encourage parents and caregivers to establish routines and enjoy conversations around books and stories with their children beginning in infancy. Research has demonstrated that parents read and children learn when pediatricians offer literacy promotion as a practical and evidence-based primary prevention strategy in primary care practice to support early brain and child development. This supports families with a strengths-based approach, shaping a child’s life trajectory and helping mitigate stress and adverse experiences.
The American Academy of Pediatrics (AAP) recommends that pediatricians encourage shared reading, beginning at birth and continuing at least through kindergarten, as a strategy for supporting parents and caregivers, enhancing foundational relationships, promoting positive language-rich interactions, and helping families create nurturing and stimulating home environments. The integration of literacy promotion into pediatric resident education is crucial to achieve that goal and thus is also essential. The AAP supports advocacy toward establishing public and private funding for diverse high-quality, developmentally appropriate children’s books in the languages preferred by the family to be provided at pediatric health supervision visits to all children but especially to children living in underresourced communities. This statement is supported by multiple AAP policies and implementation resources, including the accompanying “Literacy Promotion: An Essential Component of Primary Care Pediatric Practice: Technical Report.”
The Influence of Soviet State Policy on School Everyday Life in Kazakhstan (1945–1955)
Authors: Bimoldanova Aigul , Bekmagambetova Maisara , Bekmagambetov Ruslan 
Published: September 2024

Introduction. The work reconstructs the ideological component of Soviet children’s everyday school life in Kazakhstan, which had a huge impact on their socialization. Methods and materials. The methodological basis of the study is the theory of the sociologist P. Sztompka about the significance of “cultural trauma” in the biography of any generation of people – social tension associated with changes in society, the transformation of its values. The method of narrative interview was used in the work. Interviews were conducted with over 20 respondents whose childhood was spent in Kazakhstan in 1945–1965. Analysis. Archival data and recollections of respondents show that the school, which traditionally carried out a certain order of society, was the main mechanism in the formation of the “new Soviet person.” During the period under study, the “order” was to form a Soviet identity, with which the Soviet school and socio-political organizations represented by the pioneers and the Komsomol in Kazakhstan successfully coped. Everyday school practice reflected the ideological component of school education – all respondents, assessing their childhood from today’s standpoint, are aware of the degree of this influence. Results. A number of mechanisms were analyzed through which the official Soviet authorities formed the consciousness of the future “builders of communism”: the school, ideologized and, in fact, obligatory children’s organizations, and propaganda. The identified correspondence between the propaganda ideal and the real image of a Soviet schoolchild indicates the acceptance and assimilation of socialist values by children in Kazakhstan. The data obtained open up prospects for new research on the history of Soviet children’s everyday lives. Authors contribution. A.A. Bimoldanova proposed the idea and concept of the article and wrote the final text. M.J. Bekmagambetova prepared a historiographic review, was engaged in the identification and analysis of documentary sources from the Archive of the President of the Republic of Kazakhstan, and R.K. Bekmagambetov carried out the transcription and interpretation of the interview materials and the technical design of the text of the article. All three authors interviewed respondents.
President E. Macron and the French Political Crisis in the Aspect of the Legacy of “Gaullism”
Authors: Mulyadi Ahmad , Biryukov Sergei , Chirun Sergey 
Published: September 2024

Introduction. The presidency of Emmanuel Macron during 2017–2023 was marked by the crisis of the regime of the Fifth Republic in France. The authors propose an analysis of the origins and development of this crisis. They emphasize the complex nature of the crisis, which is not opportunistic but systemic. Materials. The research is based on the data of sociological surveys, periodical materials, and electronic sources that allow us to characterize the course and current state of the political crisis of the regime of the Fifth Republic during the presidency of Emmanuel Macron, as well as the processes accompanying it. Analysis. The authors identify and analyze the manifestations of Gaullism as an anti-crisis strategy in the policy of E. Macron. The authors are describing and analyzing the growing political crisis under the leadership of E. Macron and the causes of his government failure. The authors compare the policy of E. Macron and the political strategy of Charles de Gaulle. Results. The authors conclude that E. Macron’s selective use of elements of the Gaullist strategy in order to further legitimize and strengthen the regime of personal power does not bring final success and that French society’s trust in the current government is gradually decreasing, which contributes to the deepening of the systemic crisis of the regime of the Fifth Republic. Author’s contribution. Ahmad Mulyadi prepared a material on the use of elements of Gaullism in the politics of E. Macron, S. V. Biryukov, and S. N. Chirun – on the political process and the crisis in France.
The Theme of the East in the Society of Marxist Historians in the Second Half of the 1920s – Early 1930s
Authors: Danilov Victor 
Published: September 2024

Introduction. Oriental studies was not the leading direction in the activities of the society of Marxist historians (the second half of the 1920s – early 1930s), but it played a significant role in bringing this field of knowledge closer to the practical needs of the current policy of the All-Union Communist Party (Bolsheviks) and the Comintern. Methods and materials. The research is based on traditional methods of historiographical analysis. It uses materials from historical journals of the 1920s and 1930s and archival documents. Analysis. Reports at general meetings of the Society and the History of the East section and publications in the journal “Historian-Marxist” focused on the problems of the history of the national liberation movement in colonial and dependent countries, the policy of tsarist Russia on the southern outskirts of the empire, and socialist transformations in the national republics of the USSR. If in the early years the most influential were the well-known Marxist orientalists M.P. Pavlovich, V.A. Gurko-Kryazhin, and I.M. Reisner, then in the subsequent period Oriental historians who did not have serious scientific authority but firmly adhered to the class approach occupied the leading positions in the society. After the All-Union Conference of Marxist Historians, they focused their attention on criticizing the “old bourgeois schools” in Oriental history and “exposing pseudo-Marxism in their own ranks.” Results. However, they could achieve results in solving only the second task, using, first, discussions about socio-economic formations, about the situation and tasks at the front of the study of the East, and about the non-Marxism of Gurko-Kryazhin’s historical views. The ideological turn of the mid-1930s largely devalued the importance of the research of this generation of Marxist Orientalists, and the authorities recognized the achievements of representatives of academic Oriental studies.
Burial of a Golden Horde Nomad from the Kovalevka Kurgan Cemetery
Authors: Moiseev Vladimir , Pererva Evgeniy , Moiseeva Valentina 
Published: September 2024

Introduction. The article introduces into scientific circulation the archaeological and anthropological materials from the Golden Horde burial of the Kovalevka Kurgan Cemetery. Kurgan No. 35 dating back to the early Iron Age was studied in the course of the fieldwork carried out by the Volgograd State University expedition in the Oktyabrsky district of the Volgograd region in 2021. The Kurgan is located in the southern part of the cemetery on the upper terrace of the right bank of the river Aksai Esaulovsky in an arable field. Methods and materials. Two burials were examined because of the archaeological excavations. The main burial No. 2 dates back to the late Sarmatian period, while the intake burial No. 1 dates back to the middle age period. Analysis and results. New anthropological materials were obtained in the course of the excavations, which complement our understanding of the nomadic population from the Lower Volga region. The bone remains belonged to a male individual of mesomorphic build of about 164.5 cm tall with a long and narrow skull. A set of pathological conditions were recorded on his bones, appearing because of an active lifestyle and professional activity. The outcomes of the archaeological study of the Kurgan No. 35 from the Kovalevka Kurgan cemetery as of 2021 can be used in the museum and local history work, as well as in studies of the Lower Volga regional ancient history. Authors’ contributions. In this study, V.I. Moiseev and V.Yu. Moiseeva prepared a descriptive part of the archaeological material, carried out the funeral rites and grave goods analyses, and prepared conclusions based on the results of the research. E.V. Pererva conducted a study of anthropological material and defined the craniological, osteological, and pathological features of the individual from burial 1 of the Kurgan No. 35.
Studying and Collecting Coins of the Golden Horde in the Russian Empire in the Late 17th – Early 19th Centuries
Authors: Pachkalov Alexander 
Published: September 2024

Introduction. The purpose of the article is to find out the state of Jochi numismatics in the Russian Empire by the end of the 18th and beginning of the 19th centuries. The novelty of the research. For the first time in one work, the currently known information about the origin of the study of the coins of the Golden Horde in the 18th century is presented. The beginning of systematic coin collecting in Russia was laid by Peter I, who himself was one of the first Russian collectors and collected coins, including “Tatar” (i.e. Golden Horde) coins in his collection. Methods and materials. Numismatics is based on information from a number of human sciences: paleography, chronology, etc. Numismatics is characterized by a complex study of coins and attention to their role in historical processes. The materials for writing the article were mainly publications of the late 17th century – early 19th century, containing information about the coins of the Golden Horde. Analysis. In 1714, the Cabinet of Curiosities – the Kunstkamera – was founded in St. Petersburg. Before the emergence of the Hermitage, it was the Kunstkamera, which had its own Mintskabinet, that was the main numismatic treasury of Russia; coins from its collection later entered the Hermitage. There is evidence that Golden Horde coins were also stored in the Kunstkamera of the 18th century. The origin of private coin collecting in Russia, including Juchid coins (collections of Y.V. Bruce, A.P. Volynsky, P.I. Musin-Pushkin, etc.), belongs to the first half of the 18th century. Readings of inscriptions on coins (and, accordingly, definitions) were often erroneous. Rather, the exception is the activity of the orientalist Georg Jacob Kehr (1692–1740), who was in many ways ahead of the level of science of his time and who, judging by the surviving prints, made many correct definitions. Results. There was no systematic fixation of coin finds in the 18th century; only fragmentary information about the places of coin finds (Bolgar and Selitrennoe settlements, etc.) was preserved. At the same time, the base created in the 18th century (the development of private coin collecting, the Mintskabinet in the Kunstkamera, the activities of G.J. Kehr, etc.) contributed to bringing research to a qualitatively new level in the first half of the 19th century.
Transformation of the Model of State-Confessional Relations in Belarus at the End of the 19th Century – 1917
Authors: Lisouskaya Tatsiana 
Published: September 2024

Introduction. The article describes the process of transformation of state-confessional relations in the Belarusian lands as part of the Russian Empire from the end of the 19th century to 1917. Methods and materials. To obtain verified results, the study is based on the analysis of administrative and regulatory materials, office documents of the Mogilev diocese, and domestic and foreign historiography. The study was conducted using an interdisciplinary methodology: historical-typological and historical-comparative methods, formal-legal, and the method of interpretation of legal norms were used. In addition, to identify the features of the socio-political discourse on the issue of changes in state-church relations, discourse analysis was used. Analysis. The historically established model of a religious state with the dominance of the Orthodox Church in the Russian Empire was established in the 19th century on Belarusian lands with a different confessional structure and traditions of state-church relations. The author noted a tendency to transition from the model of a religious state to the model of a secular state – in the period March – October 1917, the Provisional Government tried to establish an identification model of a secular state. This model corresponded to the religious system of Belarusian society with the dominance of the Orthodox Church and the expectations of socio-political actors and also ensured the implementation of religious rights and freedoms of adherents of other religions but was not fully implemented due to the transfer of power to the Bolshevik Party in October 1917. Results. Transformational processes in state-confessional relations in the Belarusian provinces took place in the direction from the model of a religious state to the model of a secular state as accompanying changes in the political system of the Russian Empire. Internal factors in the development of the state-confessional system of the Russian Empire, as well as the peculiarities of the confessional environment of the Belarusian provinces (diversification of the religious structure of Belarusian society, limitation of the rights of traditional actors rooted in the Belarusian religious environment, confessional dualism “Orthodoxy-Catholicism”), did not play a significant role in the transformation processes.
Attitudes and Levels of Concern and Trust Towards COVID-19 Vaccination Among Patients Hospitalized at Shahid Beheshti Hospital in Kashan, Iran
Authors: Momen–Heravi Mansooreh , Arabzadeh Mohammad Ali , Fathizadeh Hadis , Farrahi Razieh 
Published: September 2024

Introduction: This study aimed to explore hospitalized patients' attitudes, concerns, and trust regarding Coronavirus disease 2019 vaccination.
Materials and Methods: This descriptive-cross-sectional study was conducted on 128 patients hospitalized at Shahid Beheshti Hospital in Kashan, Iran, in 2022. Participants were selected using simple random sampling. The questionnaire included questions about demographic information, attitudes towards vaccination (7 items), levels of concern (14 items), and trust (15 items). Data were analyzed using SPSS 26 software. Descriptive statistical analysis and chi-square tests applied.
Results: Fifty-three (41.4%) of cases had a history of two vaccinations. Sinopharm was used in 28.12% of patients. The average attitude score was 8.21 ± 2.88, significantly associated with age (p = 0.02), nationality (p = 0.01), education (p = 0.01), and vaccination history (p = 0.02). The mean concern score was 35.41 ± 11.87, significantly linked to gender (p = 0.01) and vaccination history (p = 0.02). The average trust score was 40.50 ± 13.64, significantly associated with age (p = 0.04), gender (p = 0.01), vaccination history (p = 0.01), hospitalization history due to COVID-19 (p = 0.03), and COVID-19 infection history (p = 0.03).
Conclusion: The vaccination rate among participants was acceptable. However, concerns about vaccination and its complications were the primary reasons for vaccine hesitancy. Given that vaccine acceptance across various community groups is as crucial as vaccine development, it is recommended that health organizations provide information on vaccine benefits and address concerns about potential side effects.