bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manifestações bucais em pacientes acometidos por leucemias agudas: uma revisão de literatura
Authors: Massote Pestana Ana Paula , Peters Ana Karolina , Rocha Floriano Ana Luisa , Casali Bomtempo Caroline , Martins Pereira Rossafa Virgínia , Tinôco Alvim de Souza Fabrício 
Published: September 2024

A leucemia caracteriza-se pela proliferação descontrolada de células originárias de uma mutação hematopoiética. Sua malignidade pode ser classificada de acordo com a linhagem celular, mieloide ou linfoide, e o modo de evolução, aguda ou crônica. As manifestações bucais podem ser os primeiros sinais em um paciente acometido por leucemia aguda, e são de suma importância para se obter o diagnóstico precoce. Foi realizado uma busca de artigos nas bases de dados, Scielo, Pubmed e Biblioteca Virtual de Saúde- BVS, entre os anos 2011 e 2024, utilizando os descritores “Acute myeloblastic leukemia”, “gingival”, “leukemia”, “Hemorrhage”. Foram levantados 70 artigos, e selecionados 30 artigos nos idiomas inglês, português e espanhol, sendo excluídos os estudos que tratavam sobre leucemia crônica e outras neoplasias que não se relacionavam com o tema. Dentre as manifestações bucais mais comuns pode-se citar o aumento gengival, úlceras orais, sangramento gengival espontâneo, petéquias, mucosa pálida, infecções virais e fúngicas. O infiltrado leucêmico se estende ao tecido gengival, causando aumento da espessura gengival e à formação de pseudobolsas periodontais, resultando em infiltração inflamatória secundária. Sendo assim, concluiu-se que para definir um diagnóstico preciso e precoce o cirurgião-dentista deve reconhecer essas alterações bucais, haja vista que podem ser um dos dos primeiros sinais da patologia; para, assim, compor uma equipe multidisciplinar a cuidar do paciente e garantir um melhor prognóstico.
Effects of Microplastic on the Gastrointestinal Tract and Gut microbiome of Sprague Dawley Rats
Authors: Baomar Taher , Al-Mahrooqi Zahra , J. Barry Michael , Al-Habsi Aziz , M.M. Abed Raeid 
Published: September 2024

ABSTRACT
Nowadays there is evidence that animals are exposed to microplastics (MPs) via food, however there is not much known about their effect on tissue of gastrointestinal tract and on gut microbiome. In this study, adult male rats were fed with polyethylene MPs, mixed with standard pellet food for 24 days at different concentrations ranging from 0 to 1000 μg/day. At the end of experiment, rats were euthanized and histopathological investigation using light and electron microscopy and the gut microbiome was analyzed using MiSeq 16S rRNA amplicon sequencing. Microscopic analysis revealed significant impact of MPs on the intestine, including visible changes to the crypt area as well as reduction in mucus secretion. Autophagic vacuoles were observed in the livers of the rats fed with MPs at 100 µg/day. Oxidative stress was evident in rats fed with 1000 µg/day of MPs, as indicated by the presence of myeloid bodies in both intestinal and hepatic cells. The gut microbiome was also affected by MPs. Although, no distinct clusters were formed when the bacterial communities in the different treatments were ordinated by multidimensional scaling (NMDS), the diversity indices including operational taxonomic unit (OTU) richness and Chao1 exhibited an increasing trend with increasing MPs concentration. Pearson correlations revealed a linear increase in the relative sequence abundance of Clostridia (R=0.036, P=0.003) with increasing MPs concentration, but not in the case of other bacterial groups,. Lactobacillus faecis was the most abundant OTU in the entire dataset, and its relative abundance decreased significantly with increasing MPs concentration. We conclude that exposure to MPs can disrupt cellular function and disturb microbiome balance, and in the event of prolonged exposure, organisms might experience unpredictable effects.
Preventive effects of dill oil on potassium bromated-induced oxidative DNA damage in garlic root tips
Authors: Khatab Hoda , Eissa Samia , S. Elhaddad Nagat 
Published: September 2024

In this study, the potential antimutagenic/cytoprotective effect of the oil extract (2.5µg/ml) from Anethum graveolens L. (Dill) on oxidative DNA damage was tested. The experiments were carried out to inhibit mutagenicity induced by potassium bromated (KBrO3-9g/l) in Allium assay using mitotic activities and nuclear DNA contents. Result showed a clear reduction in radical length in all KBrO3-treated groups compared to control plants. Mitotic activity, measured by mitotic index (MI) and mitotic stages, were significantly decreased in meristematic cells after KBrO3 application, The results showed that mitotic index (MI) was decreased to reach about 0.8 at 24 hrs compared with 23.9% in untreated plants. The analysis of potential cyto and genoprotective of dill extract on nuclear DNA contents showed a statistically significant increase in the nuclear DNA content compared to KBrO3-treated roots was observed. Clearly, dill oil showed highly performance in protecting the mitotic cells against mutagenic KBrO3 effects by increasing the MI and decreasing the abnormal chromosomes. Also, the percentage of damage reduction was observed in the pre- (28.9, 57.9 and 46.4 %), simultaneous (53.0, 70.6 and 35.7 %) and post- (37.3, 61.8 and 50 %) treatment. The results of the qualitative study showed that this dill extracts were rich in chemical compounds belonging to several phytochemical classes. GC-MS analysis detected 29 chemical compounds with different concentrations. The predominant ones were Octadecanoic acid (31.75%) and 2-pentanone, 4-hydroxy-4-methyl (16.77). So that these experiments will help to understand and uncover the mechanism of action dill oil against the mutagenic effects of KBrO3 (i.e whether they have a prophylactic or treatment activity).
Assessing Healthcare Equity in Orthopaedic Surgery: An Analysis of Over 24,000 Surgical Cases
Authors: Visco Zachary R. , Chaudry Ezan , Hudson John S. , Lim Moe R. 
Published: September 2024

Introduction:
Health disparities have been widely studied in the primary care and surgical settings. The purpose of this study was to examine surgical access disparities for orthopaedic surgical cases performed at a large academic health center by comparing the relationship between patient demographic factors and surgical wait time.

Methods:
A total of 24,778 orthopaedic surgical cases from 2018 to 2022 at a public, tertiary care, Level I trauma center were retrospectively analyzed to assess for surgical timing disparities based on patient-specific factors, including race, sex, language, and socioeconomic status.

Results:
Elective surgical cases were completed with an average surgical wait time of 28.11 ± 26.34 days. Urgent surgical cases were completed with an average surgical wait time of 1.23 ± 1.50 days. Patient race, sex, language, and socioeconomic status had no effect on surgical wait time for urgent case scheduling. Female patients had longer average wait times in elective cases, whereas race had a weak association with increased wait time. Two-factor interaction analysis showed no multifactorial effects of patient demographic factors on surgical wait time. Patient race and socioeconomic status were associated with increased distance from surgical sites, although increased distance did not correlate with increased surgical wait time.

Conclusion:
Patient demographic factors did not demonstrate clinically notable associations with surgical timing in this patient cohort, in contrast to previous studies demonstrating the effects of race and socioeconomic status on healthcare outcomes and access. Race and socioeconomic status did correlate with increased distance from surgical centers although distance from surgical sites did not correlate with surgical wait time. This contributes to previous literature on healthcare equity and indicates that surgical wait time may not contribute to the known healthcare inequalities seen in minority and marginalized patients.
De la disparition d’une lettre
Authors: Malloy Neil 
Published: September 2024

Cet article lit les traductions anglaise et américaine du Ravissement de Lol V. Stein réalisées par Eileen Ellenbogen et Richard Seaver comme le prolongement de la dynamique du ravissement à l’œuvre dans le roman de Duras. Entre capture et abandon, l’acte de traduire témoignerait de l’impossibilité de réaliser une fusion érotique et langagière avec une histoire originelle qui échappe toujours. Partant du destin des lettres dans les traductions de langue anglaise – l’absence ou l’expansion de ces éléments stylistiques si essentiels à la poétique durassienne –, l’article étudie les effets qu’impliquent les choix des traducteurs quant aux questions de musicalité, d’identité et d’érotisme. Les différences des deux traductions sont mises au jour à travers l’étude de leurs efforts pour aborder la répétition et le rythme de l’écriture durassienne. La traduction, qui ne peut que trancher dans l’ambivalence du texte source, se lit comme une forme de réappropriation subjective et nécessairement incomplète, une expression renouvelée du désir.
« Tout ce qu’on peut savoir quand on ne sait rien, je le sais »
Authors: Matthey-Jonais Eugénie 
Published: September 2024

Le texte La Douleur, de Marguerite Duras, témoigne d’une expérience nuancée du non-savoir qui se retrouve au cœur de l’écrit, dans l’intensité poignante de l’attente de Robert L. par la narratrice, mais aussi dans le paratexte ajouté lors de la publication, en 1985. La préface met en scène un non-savoir du texte par l’auteure avant même que le lecteur soit plongé dans le non-savoir produit par le décalage entre la réalité vécue par la narratrice et les discours d’information, gouvernementaux ou clandestins, qui l’entourent. La disparité entre l’expérience du non-savoir de la narratrice et les discours dominants relayés entre autres par la droite victorieuse fait ressortir une difficulté de penser le politique dans la douleur vive de la fin de la guerre. La perspective philosophique de la narration, basée sur une posture féminine affirmée, est éminemment politique.
« Lire, comme ça ou autrement »
Authors: Larmet Chloé 
Published: September 2024

La réflexion qui suit propose de mettre en regard le travail de mise en scène mené par Éric Vigner en 1993 du texte La Pluie d’été avec le modèle du théâtre lu chez Marguerite Duras. Une phrase d’Ernesto, le personnage central du roman de Duras, servira de point de départ pour éprouver l’hypothèse suivante : les mots « lire comme ça ou autrement » constituent un manifeste théâtral pour Duras autant que pour Vigner, un manifeste esthétique et dramaturgique et que l’on décomposera ici en deux temps. Lire, d’abord. Soit placer le geste théâtral sous l’égide de celui de la lecture et nous verrons ainsi de quelle façon Vigner fait du livre de Duras en tant qu’objet l’élément structurant de sa mise en scène. Une fois cet espace du livre établi, nous étudierons comment l’esthétique de Vigner repose sur une logique d’interruption qui permet au lecteur, comme au spectateur de La Pluie d’été, d’exercer sa liberté. Dans ces écarts entre les mots et les corps, quelque chose du geste de l’écriture propre à Duras devient alors sensible, une scène d’écriture qui peut se lire comme ça, ou autrement.
Des interactions verbales aux scènes romanesques chez Marguerite Duras
Authors: Doneux-Daussaint Isabelle 
Published: September 2024

La gestion des scènes dans les romans de Marguerite Duras revêt des formes très diverses. Elle peut arborer une vraie forme d’écriture scénique comme dans Le Square où aucun changement ne s’opère entre la version romanesque du texte et la version théâtrale. La scène peut aussi figurer sous le mode d’une absence dans la mesure où les principaux protagonistes en sont absents et ne la vivent qu’avec une conscience perceptive avortée. Cette scène dramatique initiale fait l’objet d’une perpétuelle reconstruction par le langage laissant en permanence échapper « la vérité » sur elle. Celle-ci prend alors la forme d’une scène de conversation. L’article étudie les diverses scènes romanesques durassiennes comme les scènes d’attente, de confidence, de disputes, les scènes érotiques, les scènes de déclaration d’amour, les scènes de rencontre et les scènes mondaines dans leur articulation avec les formes de dialogues (dilogue, trilogue et polylogue) de personnages, dans une optique de pragmatique narrative pour en faire resurgir leur mise en texte et leur rôle dans l’économie des romans. Celles-ci sont généralement traitées en détournement des codes génériques et des attentes des lecteurs.
Miopia em crianças em fase escolar e a sua relação com o tempo de exposição a telas: uma revisão integrativa
Authors: Farias Laiza Gallo , Oliveira Ivanilson Santos , Pimentel Rodrigo Fernandes Weyll 
Published: September 2024

A miopia está se tornando cada vez mais prevalente em todo o mundo e pode aumentar o risco de doenças oculares como glaucoma. A exposição prolongada a telas é um fator de risco que tem sido associado a um maior risco de desenvolvimento de miopia em crianças. Com o crescente uso de dispositivos eletrônicos pelas crianças, é importante entender melhor essa relação e avaliar as práticas de uso de telas para prevenir e tratar a miopia. Há poucos estudos que abordam esta temática no Brasil e no mundo. Este estudo tratou-se de uma análise integrativa, realizada em seis fases, conforme o modelo delineado por Mendes, Silveira e Galvão. A busca/amostragem sistematizada foi realizada por meio da busca eletrônica às bases de dados Cumulative Index to Nursing and Allied Health Literature (CINAHL), PubMed, Web of Science (Clarivate), Scientific Electronic Library Online (SCIELO), Scopus e Biblioteca Virtual em Saúde (BVS). Descritores controlados do Medical Subject Headings (MeSH) e Descritores em Ciências da Saúde (DeCS) foram utilizados para efetivar a busca bibliográfica nas bases de dados, conforme a seguinte equação: “miopia” or “myopia” and “Criança” or “Child” and " Tempo de Exposição" or " Níveis Máximos Permitidos” or Threshold Limit Values". Para determinar o nível de evidência dos artigos selecionados, adotou-se a classificação proposta pela Agency for Healthcare Research and Quality (AHRQ). O processo de seleção dos artigos resultou em um total de 139 publicações, sendo 36 excluídos devido à duplicidade, e 100 por não se relacionarem com o tema desta revisão. Foram selecionados seis artigos e os dados foram agrupados em três categorias, a saber: 1- Evidências mistas sobre o tempo de tela e miopia; 2- Impacto do tempo de tela e atividade ao ar livre nas crianças com miopia; 3- Recomendações práticas para mitigar o risco de miopia em crianças. Este estudo considerou que alguns estudos sugerem uma ligação positiva, outros não encontram uma associação significativa, destacando a necessidade de mais pesquisas bem controladas para entender melhor essa relação. Assim ações como: limitar o tempo de tela, incentivar atividades ao ar livre e adotar hábitos visuais saudáveis podem ser estratégias eficazes para mitigar o risco de desenvolvimento de miopia em crianças.
Avaliação in vitro da adesão bacteriana em superfícies de implantes submetidos a implantoplastia
Authors: Lira Jéssica Mendes Damasceno , Souza Cintya de Oliveira , Souza Júnior José Moisés de , Bianchini Marco Aurélio , Alves Júnior Sergio de Melo , Pereira Neto Armando Rodrigues Lopes 
Published: September 2024

Objetivo: O objetivo deste estudo foi avaliar o tratamento de implantoplastia para redução da adesão bacteriana nas superfícies dos implantes e investigar qual o melhor tipo de broca para realizar a implantoplastia. Materiais e Métodos: Dezoito implantes tiveram um lado da superfície alisada e o outro lado permaneceu com as características originais. Os implantes foram divididos em: Grupo 1 (n=6) broca diamantada, Grupo 2 (n=6) broca carboneto de tungstênio e Grupo 3 (n=6) broca multilaminada. Os implantes foram inoculados em 8 horas de exposição à contaminação com cepa Escherichia coli. A análise da adesão bacteriana foi realizada com Microscopia Eletrônica de Varredura (MEV). Resultados: Aplicou-se o teste t de Student, para comparar o lado tratado com o outro lado sem tratamento. Observou-se que não houve diferença significativa, Grupo 1 (p=-1,07), Grupo 2 (p=0,91) e Grupo 3 (p=0,47). Para a comparação entre o melhor desempenho das brocas, foi aplicado o teste ANOVA, onde pelo menos uma das brocas apresentou desempenho melhor, o Fcalculado (5,26) foi maior do que o Ftabelado (3,68). Para verificar qual broca teve melhor desempenho, aplicou-se o teste de Turkey, identificando que a broca diamantada era estatisticamente melhor, a DMS (Diferença Mínima Significativa) foi de 28,89. Conclusão: O tratamento de implantoplastia de forma isolada não foi o suficiente para controlar a adesão bacteriana nas superfícies dos implantes tratados e a melhor broca para ser realizada a implantoplastia é a broca diamantada.
Cuidados paliativos: compreensões da equipe de enfermagem
Authors: Oliveira Emerson Gomes de , Andrade Caio Leonardo Faria , Paula Júnior Newton Ferreira de 
Published: September 2024

A literatura científica tem demonstrado o conhecimento fragilizado dos profissionais de enfermagem acerca dos Cuidados Paliativos e seus princípios. Nesta perspectiva, esta revisão de literatura, de abordagem qualitativa, explorou as compreensões da Equipe de Enfermagem em relação aos Cuidados Paliativos. Para realização desta pesquisa, utilizou-se artigos que correspondiam ao recorte temporal de 2018 a 2024, nas bases de dados: Biblioteca Virtual em Saúde (BVS) e a Scientific Electronic Library Online (SciELO). Foram encontrados 64 artigos que, com base em critérios de inclusão e exclusão, e leitura analítica, resultaram na seleção de 05 artigos para compor o corpus desta pesquisa. Sob esse viés, observou-se que a assistência prestada aos pacientes em Cuidados Paliativos, são ações que possuem como objetivo a melhoria da perspectiva de qualidade de vida de pessoas que vivenciam doenças, ausentes de possibilidades terapêuticas de cura, que ameaçam à vida, e de seus familiares, por meio de prevenção e tratamento oportuno e precoce das manifestações clínicas do sofrimento físico, psíquico, espiritual e social. Além disso, evidenciou-se que a literatura científica enfatiza a importância da compreensão da filosofia e dos objetivos dos cuidados paliativos e destaca a necessidade de saber lidar e compreender os pacientes que estão nessa atenção, de forma holística. No entanto, foram identificadas fragilidades nas escolas formadoras dos diferentes níveis de Enfermagem e em especial na graduação e no exercício da prática de enfermagem, que são essenciais para aprimorar e atualizar o conhecimento dos profissionais no contexto dos Cuidados Paliativos.
Determination of Trace Elements Content of a Popular Traditional Herbal Medicine Used for Internal Hemorrhoids Treatment in Katsina State, Nigeria
Authors: Bello Suleiman , Gide Muhammad Bashir , Rufai Usman Ahmad , Gambo Lawal Mukhtar , Abubakar Hussaini 
Published: September 2024

Study’s Excerpt/Novelty

Assessment of toxic metal concentrations of a widely used traditional herb in Katsina state, was carried out.
Flame atomic absorption spectrophotometry and descriptive statistical analysis was employed in the research.
Pb, Cr, and As were found to be beyond WHO/FAO thresholds.

Full Abstract
There has been an increase in the utilization of traditional herbal drugs for different medications and health care in Katsina state. This is possibly due to the growing need for complementary disease treatment, relative cheapness, availability, and wider distribution. Raw samples of a popularly used traditional herb (locally named - Dan Lambar Rimi) were purchased from local markets, prepared, and analyzed using a flame atomic absorption spectrophotometer for Pb, Cr, As, Co, Ni, and Cd concentrations. The obtained concentrations were then summarized using descriptive statistics in SPSS Version 27. The results for the elements analyzed were Ni (0.83 ± 0.15), Cd (0.20 ± 0.01), Pb (21.5 ± 6.63), As (2.10 ± 0.70), Cr (2.36 ± 0.37), and Co (1.15 ± 0.22) ppm. Cr, Pb and As concentrations were greater than the WHO/FAO threshold limits for herbal medicines, while that of Cd was within the recommended threshold. Furthermore, the concentrations of these metals (As, Cr, and Pb) were greater than the WHO/FAO acceptable threshold in 50% of the herbal samples analyzed. Therefore, these metals can pose a threat to public health, especially considering the conventional way in which this herbal medicine is used. With deliberate improvement in hygiene during its preparation prior to consumption, the risk will be brought to a minimal. Future studies should perform a detailed chemical risk assessment, especially when we look at the increase in the number of diseases of unknown etiology in the region.
The development of flexibility in people of mature age through hatha yoga
Authors: Rogov O. S. , Mikhailova O. V. 
Published: September 2024

Relevance: The level of flexibility development, along with other indicators, determines the level of human health. New approaches to the content of wellness classes for middle-aged and mature people have been developed and substantiated. Physical activity and physical exercises of a health-improving orientation are necessary throughout life. At the same time, each stage of age-related development is characterized by certain features of conducting activities and their orientation. For example, before the age of 35-40, when assimilation processes prevail in the body, classes should have a developmental orientation, and after 40 years - mainly preserving health.The aim of the study is to increase flexibility in women aged 30-45 years through hatha yoga classes.Organization and methods of research. The study involved women aged 35 to 45 years old who practiced yoga at the Lanfen studio in Yekaterinburg for 3 months. The generally accepted Indian method of teaching hatha yoga was used, which is characterized by performing a set of "asanas", which are canonized, typical yoga poses, with a delay in each pose from a few seconds to a minute or more with a slow transition from one pose to another. As a rule, the exercises were performed with low intensity using the principle of absolute concentration on the final result of their actions, as well as compliance with the rules of exercise (consistency and breathing).The results of the study and their discussion. The experimental data obtained in the course of the study allow us to assert that the model of the educational and training process aimed at developing the quality of flexibility, where special attention is paid to warm-up using intensive gymnastics and summing exercises, static-strength and corrective exercises, stretching and relaxation exercises, is really effective in relation to a young age and our climatic conditions. The main provisions of the work can be applied in the professional activities of specialists in the field of recreational physical culture and fitness, in physical culture and wellness work with other population, as well as for the development of flexibility among representatives of various sports.Conclusions. An experimental technique was developed to improve the quality of flexibility, and a pedagogical experiment was conducted for three months. The technique included joint warm-up, a dynamic complex "Surya Namaskar", 3 main complexes, and restorative asanas with pranayama to improve the quality of flexibility. The technique has shown its effectiveness. The overall flexibility indicators of the women tested increased, especially the mobility of the spine improved, since the spine is primarily rebuilt and stretched in this technique.