bluuebunny/crossref_metadata_2025_split huggingface dataset:
Involvement of the trigeminal nerve secondary to GBM of the cerebellar peduncle – Atypical presentation in a single case
Authors: Fernandes Sérgio Tadeu , Guimarães Toloi José Ricardo , Thimoteo da Silva Pedro Paulo 
Published: January 2018

AbstractGlioblastoma multiforme (GBM) is the most frequent and malignant glial tumour and mainly affects adults aged between 45 and 65 years.1,2 It typically occurs in the cerebral hemispheres, although other locations and related clinical manifestations are described in the literature.1,2 The clinical, neuro-radiological, surgical and neuro-pathological findings are reported of a 44 year-old female patient, who appears to represent the first case of involvement of the trigeminal nerve secondary to infiltration by GBM of the cerebellar peduncle.
Giant pericallosal artery aneurysm – Literature review and report of a rare case
Authors: Guedes Corrêa José Fernando , Sucussel Junior Ari Boulanger , Pires Amorim Rogério Martins , Loiola Lucas Santos , Reis Maristella , Megali Raquel 
Published: January 2018

AbstractGiant pericallosal artery aneurysms are extremely rare. Aneurismatic lesions involving this artery are usually small, tend to early bleeding and might be associated with other lesions. Differential diagnosis of giant aneurysms are not easy and includes tumoral, infectious and vascular mass effect lesions. We report a case of a giant and partially thrombosed left pericallosal artery aneurysm. A 58-year-old man, presented with progressive headaches, seizures and speech alterations initially misdiagnosed as a falx cerebri meningioma. As clinical status continue to worsen, magnetic resonance imaging and digital cerebral angiography were performed and a vascular etiology was considered. The patient was then referred to our hospital for surgical treatment. The peculiarity of this case concerns the difficulty of surgical treatment once the surgeon was not able to obtain control of the afferent artery and the aneurysm neck could not be visualized. Also, the aneurysm adhered to the medial surfaces of the frontal lobes and covered the anterior cerebral arteries. Treatment by means of microsurgical thrombectomy, clipping and resection of the lesion was successfully performed. Microsurgical treatment may provide good results when carefully planned with the help of imaging studies of the lesion. It is essential to keep in mind that flexible approach is of great importance when dealing with giant aneurysmatic lesions of pericallosal artery due to its variety of intraoperative presentation.
“Sinal do redemoinho” em hematoma extradural hiperagudo
Authors: Pereira Carlos Umberto , Andrade Santos Liani Patrícia 
Published: January 2018

Resumo
Objetivo: O presente trabalho apresenta o significado do sinal do redemoinho, que é observado no exame de tomografia computadorizada (TC) em casos de hematoma extradural hiperagudo. Métodos: Foram estudados 12 pacientes com hematoma extradural hiperagudo e que apresentaram sinal do redemoinho ao exame de TC. Resultados: O sexo masculino foi o mais acometido 10:2 feminino. Nove pacientes foram vítimas de acidente de trânsito, dois de queda de altura e um de agressão física. A localização do hematoma foi parietal (sete casos), frontal (três casos) e temporoparietal (dois casos). O sinal do redemoinho foi diagnosticado na TC em todos os casos e confirmada no ato cirúrgico sua relação com sangramento arterial ativo em nove casos. Conclusão: O sinal do redemoinho observado na TC em pacientes com hematoma extradural hiperagudo indica que se deve realizar drenagem cirúrgica urgente, uma vez que sua persistência implica aumento de volume e, consequentemente, aumento da morbimortalidade.
Tratamento cirúrgico para automatismos sexuais em crises parciais complexas: relato de caso e revisão da literatura
Authors: Wanderley Filho Luiz Eduardo Ribeiro , Lelis Lucas Chaves , Portella Junior Caio Sander Andrade , Souza Yuri Andrade , Souza Vitor Andrade 
Published: January 2018

ResumoRelatamos caso raro de crises parciais complexas com automatismos genitais secundárias a tumor temporal. Paciente foi submetida à lobectomia temporal direita com remissão completa dos sintomas. Após revisão da literatura, fica evidenciado que crises podem ser originadas tanto no lobo frontal quanto temporal.
Spinal intramedullary cysticercosis: a case report and literature review
Authors: Santos Araujo Audrey Beatriz , Ribeiro Cambraia Marina Brugnoli , Motta Filho Ricardo Azevedo Moraes , Rezende Gláucia Lara , Vanderlei Alander Sobreira 
Published: January 2018

AbstractNeurocysticercosis is an endemic infeccion in Brazil, but the intramedullary cases are rare, 1,2% to 5,8% of all cases. There are only fifty cases reported until January of 2011. Intramedullary neurocysticerosis is a treatable pathology but if misdiagnosed it could lead to irreversible damage. Twenty eight year old female patient, previously healthy, was admitted due to a fall. She had progressive walking difficulties and impaired sensation in both lower limbs two months before admission. Contrast MRI revealed a round intramedullary cystic lesion at T2 e T3. The patient underwent laminectomy from T2 to T3, and the spinal cord was found locally swollen near the exit root at this level. A mielotomy was performed where a round protrusion was seen near the root. Histological examination of the resected sample showed cysticercosis. After surgical excision she received albendazol and streoids. The patient's neurological function postoperatively was unchanged. One week later, the motor power of her lower limbs were grade 4/5, and she could walk without special support. The function of anal sphincter and bladder regained without compromise. She was back to work. This reflects dramatically in an active portion of population since it affects mostly people between 20 to 45 years. So it still represents a challenge and this paper intend to show our experience and by that help future diagnostics.
Meningocele sacral anterior associada a fístula retotecal e meningite polimicrobiana: relato de caso
Authors: Simon Sola Rodrigo de Almeida , Ferreira Gonçalves Bruno Leonardo Zappa , Almeida e Silva André de , Navarro Juliano Nery , da Silva Junior Nilton Rocha , Brito Leandro Gomes , Carneiro Pontelli Luis Otavio , Abreu Mattos Luiz Gustavo de , Mattos Araujo João Flávio 
Published: January 2018

ResumoMeningoceles sacrais anteriores são exemplos raros de disrafismo espinhal, originados da herniação do saco dural, através de um defeito ósseo na parede anterior sacrococcígea. Essa condição foi descrita pela primeira vez em 1837 por Bryant, e existem, aproximadamente, 250 casos relatados até os dias atuais. A tríade defeito ósseo, malformação anorretal e massa pré-sacral configura a síndrome de Currarino, e tal massa pode consistir de um tumor, de uma meningocele sacral anterior ou da associação de ambos. Tal síndrome apresenta incidência desconhecida, e acredita-se que seja uma desordem de transmissão autossômica dominante. O diagnóstico ainda é desafiador, apesar da evolução dos exames de imagem. Tomografia computadorizada (TC) e ressonância magnética (RNM) são primordiais, sendo a última o melhor exame para caracterização. A radiografia simples pode ajudar demonstrando o defeito ósseo sacral e o sacro em “cimitarra”, sendo indicada para triagem de transmissão familiar. A maioria dos pacientes apresenta constipação e sintomas vesicais compressivos. A meningite é uma complicação rara e séria da meningocele sacral anterior, e a associação entre fístula retotecal e pneumoencéfalo foi relatada em apenas dois artigos de língua inglesa. O tratamento deve ser cirúrgico, uma vez que não há possibilidade de fechamento espontâneo. Em casos não tratados ou com atraso diagnóstico, a mortalidade é superior a 30% quando associados à infecção. Descrevemos um caso de meningocele sacral anterior acometendo uma jovem de 17 anos, assintomática até então, que apresentou meningite polimicrobiana como quadro inicial devido a uma fístula retotecal.
Hemorrhagic intracranial distal (cortical) dissections: five cases and a literature review
Authors: Albuquerque Peres Carlos Michel , Anxionnat Rene , Bracard Serge 
Published: January 2018

Abstract
Objective: To describe and analyze five cases of symptomatic intracranial spontaneous cortical dissections and a review of the literature relating to this disorder. Method: Retrospective analysis of patients undergoing investigation for intracranial hemorrhage. Data were compiled from the medical file and PACS of the Nancy University Hospital. Results: Of 350 patients who underwent investigation for spontaneous intracranial hemorrhage, five patients (four women) harbored intracranial distal dissections, with no evidence of infection, trauma, arterial hypertension, vasculitis. The patients age ranged from 35 to 77 years (mean age 50.8 years). No patient presented with a poor grade SAH (Hunt and Hess grade IV or V). All patients presented with headache. The localization of the vessel abnormality was equally distributed between the anterior and posterior circulation. All patients, except one, harbored an aneurysmal sac angiographically detectable. Conclusion: Dissecting aneurysms of the intracranial distal/cortical arteries are exceedingly rare vascular lesions that produce neurologic symptoms related to their topography and hemorrhagic or ischemic nature. In the aneurysmal forms, the treatment in an urgent fashion may be considered if we consider the risk of re-hemorrhage. The first-choice treatment is coil occlusion of the involved artery at the level of the dissection.
Pacientes com traumatismo cranioencefálico tratados cirurgicamente no serviço de neurocirurgia do Hospital de Base do Distrito Federal (Brasília-Brasil)
Authors: Tavares Cléciton Braga , Sousa Emerson Brandão , Campbell Borges Igor Brenno , Almeida Gomes Braga Francisca das Chagas Sheyla 
Published: January 2018

Resumo
Objetivo: O traumatismo cranioencefálico (TCE) é uma agressão ao encéfalo causada por uma força física externa. No Brasil, é a principal causa de morte de crianças acima de 5 anos de idade e adolescentes. Apresentamos as características epidemiológicas de 194 pacientes com TCE operados no serviço de neurocirurgia do Hospital de Base do Distrito Federal. Métodos: Trata-se de um estudo descritivo, tipo corte transversal, baseado na revisão de prontuários médicos de pacientes com TCE tratados cirurgicamente no período de julho de 2007 a julho de 2012. Resultados: Predomínio do sexo masculino (82,99%); a faixa etária mais comum é de 21-40 anos (67); a maioria apresentava TCE grave (108) e o principal mecanismo do trauma foi agressão física (57) seguida por queda da própria altura (49). Hematoma subdural crônico (63), hematoma extradural agudo (49) e fratura com afundamento (38) foram os principais achados tomográficos. Há uma relação entre hematoma subdural crônico (p < 0,05/OR = 1,272/IC 95%: 1,163-1,391), hematoma subdural agudo (p = 0,008/OR = 3,271/IC 95%: 1,309-8,172) e atropelamento (p < 0,05/OR = 8,804/IC 95%: 2,203-35,185) com TCE grave. Conclusão: A maioria dos pacientes era do sexo masculino, na faixa etária entre 21-40 anos, vítima de agressão física e admitida com TCE grave. Há relação entre atropelamento, hematoma subdural agudo e crônico com a gravidade do TCE.
Amyloidosis presenting as multiple vertebral fractures
Authors: Botelho Ricardo Vieira , Fernandes de Oliveira Matheus , Rotta José Marcus 
Published: January 2018

AbstractAmyloidosis is a plasma cell disorder characterized by the overproduction and tissue deposition of a monoclonal IG light chain or fragments. Musculoskeletal and soft tissue manifestations are arthropathy, myopathy, bone lesions, and lymphadenopathy. It can also present with symptoms and signs that mimic a variety of rheumatic conditions, such as scleroderma, rheumatoid arthritis, Sjögren's syndrome polymyalgia rheumatica, a myeloma or a bone tumour. We describe the case of a 64-year-old white woman with an acute history of fall from own height in whose investigation revealed fractures in T8, T9, T11 and L1. In order to determine the nature of lesion, the patient was submitted to percutaneous biopsy guided by fluoroscopy of T11, without any surgical complications. Pathological findings were compatible with deposition of amyloid protein and amyloidosis. Amyloidosis must be considered in differential diagnosis of pathological fractures together with other osteopenic and lytic conditions, such as bone metastasis, metabolic and infectious diseases.
Revisão de literatura e relato de caso de fístula arteriovenosa craniana cutânea pós-traumática
Authors: Junior Jefferson Rosi , Gadelha de Figueiredo Eberval , Yeng Lin Tchia , Teixeira Manoel Jacobsen 
Published: January 2018

ResumoOs autores descrevem o caso de um doente de 34 anos que, após agressão sofrida em 2008, detectou o surgimento de tumoração no mesmo local em que sofrera a agressão, onde surgiu uma fístula arteriovenosa cutânea pós-traumática, documentada por meio de angiografia digital. Tanto o doente quanto a equipe médica optaram por conduta não cirúrgica, e o doente segue assintomático no seguimento ambulatorial, sem modificação da fístula desde seu diagnóstico.
Tratamento cirúrgico das lesões traumáticas do plexo braquial
Authors: Rodrigues Daniella Brito , Carvalho Viegas Maria Luana , Rogério Juvenal de Souza , Rodrigues Pereira Edmundo Luis 
Published: January 2018

ResumoAs lesões do plexo braquial são frequentemente causadas pela avulsão de raízes nervosas após acidentes automobilísticos de alta energia e geralmente afetam homens jovens, resultando em déficits neurais com elevado potencial de incapacidade grave e permanente. O presente estudo tem como objetivo revisar a literatura pertinente ao tratamento cirúrgico das lesões traumáticas do plexo braquial, ressaltando as principais técnicas e indicações. São discutidas as quatro técnicas cirúrgicas mais comumente utilizadas: reparação direta nas lacerações agudas, neurólise externa, enxertos de nervos e transferência de nervos. Além disso, são analisados a anatomia, a fisiopatologia e os fatores que influenciam a recuperação funcional: idade, intervalo entre a lesão e cirurgia, estado dos dois sítios de coaptação, enxertos de nervos longos, tecido cicatricial, isquemia e grau de lesão da raiz nervosa. A reparação direta é mais utilizada em lacerações agudas, e a transferência de nervos tem se mostrado a técnica cirúrgica mais eficaz, principalmente em combinação com os enxertos de nervos.
Aplicação da escala SF-36 em pacientes operados de tumores da base do crânio
Authors: Servelhere Katiane R. , Fernandes Yvens B. , Ramina Ricardo , Borges Guilherme 
Published: January 2018

Resumo
Introdução: A base do crânio é uma região que pode ser afetada por diferentes tipos de tumores. Os tumores dessa região podem ser benignos ou malignos e se localizarem na cavidade anterior, média ou posterior do crânio. Embora relativamente raras, essas lesões podem afetar significativamente os pacientes em virtude de sua localização anatômica complexa e riscos próprios do manejo cirúrgico. A qualidade de vida de pacientes operados de tumores da base do crânio pode ser prejudicada não somente pelo comprometimento neurológico resultante da lesão anatômica, mas também por problemas psicossociais tais como diminuição da autoconfiança e autoestima, mudança nas atividades de vida diária, dependência, estigma, discriminação, dificuldade de interação social, desemprego, entre outras. Dessa forma, o objetivo deste estudo foi avaliar a qualidade de vida dos pacientes operados de tumores da base do crânio. Método: O estudo incluiu 38 indivíduos que foram avaliados entre seis meses e um ano após a cirurgia usando a escala de qualidade de vida SF-36. Resultados: Todos os pacientes tiveram pontuação acima de 50. Em seis dos oito domínios, nos componentes físico e mental, mulheres pontuaram melhor que homens, especialmente em LAF (limitação por aspectos físicos). Quando comparadas as idades, pacientes acima de 50 anos pontuaram melhor. Quando comparados os sexos, mulheres até 50 anos pontuaram melhor que os homens. Por outro lado, homens com idade superior a 50 anos pontuaram melhor que as mulheres. Conclusão: Embora haja diferenças, estas não foram estatisticamente significantes. Assim, não houve melhora significativa nos quesitos social, físico, psicológico e funcional quando idade e sexo foram comparados.
Atypical teratoid/rhabdoid tumor of the brain – A case with three secondary implants
Authors: Biasi Pedro Radalle , Crusius Paulo Sérgio , Seibert Cláudio Albano , Crusius Marcelo Ughini , Carazzo Charles André , Crusius Cassiano Ughini , Forcelini Cassiano Mateus , Mallmann Adroaldo Baseggio 
Published: January 2018

AbstractAtypical teratoid/rhabdoid (AT/RT) of the brain is a rare malignant pediatric neoplasm that usually affects children around age two. This report is about a male patient, six months of age, who presented with seizures and decreased level of consciousness, progressing to numbness, oculomotor nerve palsy and tetra-spasticity. CT scan showed left cerebellopontine angle tumor. Magnetic resonance imaging (MRI) showed a solid lesion, hypointense on T1W and heterogeneous hyperintense on T2W, enhanced after contrast infusion, accompanied by three solid lesions, rounded and irregular in the left cerebellar hemisphere, occipito-parietal transition and right occipital lobe with no evidence of leptomeningeal spread, forming secondary implants. We conducted a biopsy, which confirmed AT/ RT. Chemotherapic treatment was ineffective and the patient passed away quickly. In the literature review we found about 300 cases reported, as it is, therefore, extremely rare tumor with a mean age at diagnosis of 29 months. It can affect any area of the central nervous system, mainly infratentorial, being its main differential diagnosis medulloblastomas. The findings of secondary implantation without leptomeningeal spread seen in this patient are described in only one other case in literature. The clinical features usually are neurological deficits, seizures and coma. Its genesis stems from mutations in the gene hSNF5/INI1 on chromosome 22. Neuroimaging studies don’t reveal radiological pattern suggesting AT/RT and the diagnosis is possible only through a biopsy with immunohistochemical analysis. The available treatments are ineffective, and death is the outcome, with 84% in six months.
Association Between Body Weight Change Before and After Delivery and Development of Nonmetabolic Syndrome: A Prospective Study
Authors: Ya Zhao , Yue Zeng , Dan Liu , Neng-bo Lin , Yi Luo , Ying Miao , Qin Wan 
Published: January 2018

AbstractThe aim of the work was to investigate the association between body weight change before and after delivery and development of nonmetabolic syndrome in Chinese females aged ≥40 years. We selected 789 participants without metabolic syndrome randomly from a baseline survey performed in Luzhou, China in 2011. We took the group with decreasing or no increasing body mass index difference during a pregnancy as “R-Body Mass Index 1” (n=286) and divided the group with increasing body mass index difference during a pregnancy into “R-Body Mass Index 2” (n=254) and “R-Body Mass Index 3” (n=249) based upon P50. All study participants were followed up every year, and a questionnaire, physical examination, and biochemical detection were administered after 3 years. Of 789 participants, 82 nonmetabolic syndrome women developed metabolic syndrome during 3-year follow-up. The morbidity of metabolic syndrome in the R-BMI1, R-BMI2, and R-BMI3 groups was 5.2%, 11.8%, and 14.9%, respectively. Compared to the R-BMI1 group, the relative risk for R-BMI2 was 1.92 (95% confidence interval: 1.03–3.58, p=0.040) and for R-BMI3 was 2.20 (95% confidence interval: 1.20–4.03, p=0.011). After adjusting for age, BMI, WHR, baseline blood glucose, HbA1c, TG, HDL-C, SBP, DBP, age of menarche and menopause, and delivery times, the relative risks were similar to the unadjusted relative risks. In conclusion, body weight change after delivery was associated with metabolic syndrome: the higher the weight gain, the higher the risk of metabolic syndrome.
Sertindole: EEG Analysis, Tolerability, and Clinical Efficacy
Authors: Kroc Adam , Dębicka Marta , Wierzbicka Aleksandra , Wołkow Lidia , Jernajczyk Wojciech , Wichniak Adam 
Published: January 2018

Abstract
Introduction One of the common side effects of antipsychotic drugs is excessive sedation. The treatment with antipsychotics often manifests as an increase in slow wave activity in electroencephalography (EEG). The aim of this study was to analyze EEG recordings of patients treated with a non-sedative antipsychotic drug sertindole with regard to its adverse effects and clinical efficacy.
Patients and methods EEG recordings of 45 patients (27 females, mean age 30.1±8.7 years) with schizophrenia were analyzed. EEG recordings were categorized based on abnormalities severity. The clinical efficacy was rated on the Clinical Global Impression Scale.
Results Abnormalities from mild to moderate were found in 29% of the group. Clinical improvement was observed in 80% of patients. Sedation/daytime sleepiness was present in 7% of patients. Other side effects were prolongation of QTc (11%, severe 4%), insomnia (9%), extrapyramidal symptoms (7%), and heart palpitations (2%).
Conclusions Patients treated with sertindole do not show side effects similar to those found during treatment with other antipsychotic drugs. Increased slow wave activity in EEG and sedation were absent in the majority of the investigated patients.
Creative entextualizations of discourses about race in multi-sited discursive practices in the Brazilian ‘periphery’
Authors: Guimarães Thayse Figueira , Moita-Lopes Luiz Paulo 
Published: January 2018

Abstract
This paper focuses on Luan’s race performances both on the web and in classroom interaction. Luan is a black young man, who identifies himself as gay. The study is part of a multi-sited ethnographic piece of research on a group of high-school students in the state sector, in the ‘periphery’ of a town on the Rio de Janeiro State north coast, Brazil. The paper is guided by performance and entextualization theorizing. The analysis draws attention to the circulation of racial identity signs, intersected with gender/sexuality meanings, bringing to light what we call creative entextualizations, i.e. the gaps Luan finds to re-organize the meanings in the discursive practices in which he is engaged. The analyses point to positionings and innovative identity performances which come up in conjunction with essentialized views, always perceptible amidst struggles and disputes. Because it draws attention to mobile lives in the ‘periphery’, this study may be said to explode the traditional boundaries between ‘center’ and ‘periphery’.
A Note on the 2017 Landmark US Ruling on the Constitutionality of Prohibiting the Trademarking of Potentially Disparaging Names
Authors: Nick I. M. 
Published: January 2018

The Lanham Act was enacted by the US Congress in 1946 with the overall purpose of regularizing the nation’s registration and use of trademarks. Despite undergoing a number of amendments since its enactment, for the past 70 years, the Act has continued to provide key federal protections against not only the unlawful or deceptive use of trademarks. It also strictly forbad the registration of marks that reasonably could be considered immoral, scandalous, contemptuous, or disparaging. Though hailed by some as an important protection against hateful speech in the public marketplace, others have questioned whether the statute violates the constitutional right to Freedom of Speech. This year, the US Supreme Court issued a ruling that put an official end to this legal controversy. This article provides a detailed description of the case that led to this landmark decision and discusses some of the potential implications for trademarking potentially disparaging brand names.