bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Deposition Conditions on Atmospheric Pitting Corrosion Location Under Evans Droplets on Type 304L Stainless Steel
Authors: Street Steven R. , Cook Angus J.M.C. , Mohammed-Ali Haval B. , Rayment Trevor , Davenport Alison J. 
Published: December 2017

Pit location during atmospheric corrosion of Type 304L stainless steel under MgCl2 droplets depends on initial droplet concentration. Pits formed predominantly in the center of the droplet for concentrations ≥4 M, closer to the perimeter for 1.5 M to 3 M, and were randomly distributed for concentrations ≤1 M. Pits initiated only after the droplets had evaporated to a critical concentration &gt;3 M, where droplets deposited with lower initial concentrations were thinner. The results can be explained in terms of “differential aeration” and IR drop effects, showing that corrosion in “splash zones” may differ from that under aerosol salt deposit layers that deliquesce forming initially saturated solutions.
Validation of spectroscopic gas analyzer accuracy using gravimetric standard gas mixtures: impact of background gas composition on CO2 quantitation by cavity ring-down spectroscopy
Authors: Lim Jeong Sik , Park Miyeon , Lee Jinbok , Lee Jeongsoon 
Published: December 2017

Abstract. The effect of background gas composition on the measurement of CO2 levels was investigated by wavelength-scanned cavity ring-down spectrometry (WS-CRDS) employing a spectral line centered at the R(1) of the (3 00 1)III  ←  (0 0 0) band. For this purpose, eight cylinders with various gas compositions were gravimetrically and volumetrically prepared within 2σ = 0.1 %, and these gas mixtures were introduced into the WS-CRDS analyzer calibrated against standards of ambient air composition. Depending on the gas composition, deviations between CRDS-determined and gravimetrically (or volumetrically) assigned CO2 concentrations ranged from −9.77 to 5.36 µmol mol−1, e.g., excess N2 exhibited a negative deviation, whereas excess Ar showed a positive one. The total pressure broadening coefficients (TPBCs) obtained from the composition of N2, O2, and Ar thoroughly corrected the deviations up to −0.5 to 0.6 µmol mol−1, while these values were −0.43 to 1.43 µmol mol−1 considering PBCs induced by only N2. The use of TPBC enhanced deviations to be corrected to ∼ 0.15 %. Furthermore, the above correction linearly shifted CRDS responses for a large extent of TPBCs ranging from 0.065 to 0.081 cm−1 atm−1. Thus, accurate measurements using optical intensity-based techniques such as WS-CRDS require TPBC-based instrument calibration or use standards prepared in the same background composition of ambient air.
RUBBER CITY GIRL: THE PATH TO THE GOODYEAR MEDAL
Authors: Puskas Judit E. 
Published: December 2017

ABSTRACTAn overview of my 40-year career will be provided, spanning both industry and academe, and two continents. During my industrial years at LANXESS (formerly the Rubber Division of Bayer), I solved long-standing (10-yr) major manufacturing problems related to Taktene-55 and developed on-line and off-line process control tools that are still in operation. I also developed new technologies (bimodal butyl, one-step halobutyl, branched butyl, liquid carbon dioxide process) that resulted in patents. After transferring to academe, I continued the development of new polyisobutylene-based materials. I have held the Bayer (LANXESS) Industrial Research Chair for 12 yr, working closely with the rubber industry. My most important accomplishments include developing advanced elastomers and thermoplastic elastomers for health care, enzyme-catalyzed polymer functionalization, a “green” synthesis of disulfide polymers and gels, and research into natural rubber biosynthesis. Poly(styrene-isobutylene-polystyrene) is used in a Food and Drug Administration–approved drug-eluting stent, implanted in more than six million patients, saving lives. The recently patented poly(alloocimene-isobutylene-alloocimene) is also a potential biomaterial and also a potential halogen-free halobutyl rubber. I will also discuss my adventure of a field experiment at a Brazilian Hevea plantation to verify our laboratory discovery that the rubber content of Hevea latex can be increased by 20–50% using a special method of tapping. My goal now is creating safer breast implants with cancer-fighting and healing properties. I am proud that the Rubber World trade journal listed me among the 125 inventors that influenced rubber technology in a profound way. I thank my family, Professor Joseph P. Kennedy, and Dr. Adel Halasa for their mentorship and support.
Outcomes in patients with late sequelae (healed stage) of Legg-Calvé-Perthes disease undergoing arthroscopic treatment: retrospective case series
Authors: Lee Woo-Yong , Hwang Deuk-Soo , Ha Yong-Chan , Kim Pil-Sung , Zheng Long 
Published: December 2017

Introduction: The residual hip deformities after Legg-Calvé-Perthes disease (LCPD) cause mechanical symptoms and are associated with a pathomechanical environment that can feature femoroacetabular impingement (FAI). The aim of this study is to evaluate the clinical and radiological outcomes in residual or healed LCPD after arthroscopic treatment. Patients and methods: We retrospectively reviewed patients with LCPD amongst patients with FAI who underwent arthroscopic treatment between January 2009 and June 2013. We determined LCPD through 3-dimensional computed tomographic scans and simple radiography of the hip joint. The clinical outcomes were rated using a visual analogue scale pain score (VAS), the modified Harris Hip Score (mHHS) and hip range of motion (ROM) preoperatively and at the 2-year follow-up. All radiographs were assessed using the Tönnis classification system preoperatively and at the final follow-up of each patient. There were 23 patients (14 men, 9 women) with mean age 26.4 (range, 16-49) years undergoing arthroscopic treatment for FAI symptoms because of residual or healed LCPD. Results: At the 2-year follow-up, the mean VAS had improved significantly from 6.7 to 2.1, the mean mHHS had improved significantly from 62.6 to 87.4, and hip flexion and external rotation had improved significantly from 88.7° to 106.5° and from 20.4° to 33.5°, respectively (all p<0.001). The Tönnis osteoarthritis grade had not changed in any patient at the latest follow-up. Conclusions: Arthroscopic treatment for sequelae of LCPD relieved symptoms and improved range of motion, making arthroscopic treatment a good option for the sequelae of LCPD.
Overestimation of the risk of revision with Kaplan-Meier presenting the long-term outcome of total hip replacement in older patients
Authors: Lampropoulou-Adamidou Kalliopi , Karachalios Theofilos S , Hartofilakidis George 
Published: December 2017

Introduction: The purpose of the present study was (i) to review the long-term outcome of cemented Charnley total hip replacements (THRs) performed by 1 surgeon (GH), 20 to 42 years ago, in patients ≥60 years, using both the Kaplan-Meier (KM) and the cumulative incidence (CI) methods, and (ii) to compare the estimations of the 2 statistical methods. Methods: We evaluated the outcome of 306 consecutive primary cemented THRs that were performed in 265 patients. The final clinical, radiographic assessment and satisfaction of living patients were also included. The survivorship was estimated with the use of KM and CI methods and the relative difference between their estimations was calculated. Results: Living patients’ final clinical results were significantly improved in comparison with respective preoperative ones, and all the acetabular and 91% of femoral components considered as well fixed. 95% of these patients reported satisfaction. The risk of revision at 25 years, with revision for aseptic loosening for 1 or both components as the endpoint, with 21 hips at risk, assessed with KM analysis was 6.9% and with CI approach was 3.9%. The relative difference between KM and CI estimations was increasing during follow-up, reaching up to 76.8% at 25 years. Conclusions: We concluded that fixation of implants with cement in older patients had satisfactory long-term results and can serve as a benchmark with which to compare newer fixation methods (hybrid and uncemented) and materials. However, KM method, in studies that include older population with long-term follow-up, may significantly overestimate the risk of revision and clinicians could consider using besides the cumulative incidence of competing risk method.
Leg length discrepancy after total hip arthroplasty: comparison of 3 intraoperative measurement methods
Authors: Nossa Juan M , Muñoz Juan M , Riveros Emilio A , Rueda Guillermo , Márquez Diego , Pérez Javier 
Published: December 2017

Introduction: Total hip arthroplasty (THA) is 1 of the most successful and frequent orthopaedic procedures around the world. Leg length discrepancy is reported in 1% to 60% of cases and is 1 of the most frequent causes of patient dissatisfaction and a common reason for litigation. The aim of this study was to compare leg length discrepancies following THA using 3 different intraoperative measuring methods. Material and methods: We present a prospective cohort study of 454 hips undergoing THA for osteoarthritis between January 2009 and August 2016. We compared postoperative leg length discrepancy using 1 of the following 3 measurement methods: (1A) direct intraoperative comparison of the legs; (1B) measurement with a compass-like device with supra-acetabular fixation, involving length and offset; (1C, D) an intraoperative device that measures the trochanteric/joint ratio. Results: Leg length discrepancy >5 mm was present in 26% of the total study population. Direct intraoperative leg-to-leg assessment resulted in the greatest proportion of leg length discrepancy >5 mm (31%), followed by the compass group (27%) and the least discrepancy was observed in the trochanteric/joint ratio group (15%). The trochanteric/joint ratio assessment method resulted in the greatest reduction in discrepancy when compared to the other methods: discrepancies of 5-10 mm fell by 48% (relative risk [RR] 0.40 CI [confidence interval [CI] 95%, 0.22-0.74), and discrepancies of ≥10 mm fell by 59% (RR 0.52; CI 95%, 0.32-0.84). Conclusions: We conclude that the use of an intraoperative measurement device can reduce the leg length discrepancy, with best results when using the trochanteric/joint ratio device.
Cephalic Vein Transposition is a Durable Approach to Managing Cephalic Arch Stenosis
Authors: Henry Jon C. , Sachdev Ulka , Hager Eric , Dillavou Ellen , Yuo Theodore , Makaroun Michel , Leers Steven A. 
Published: December 2017

Introduction The proximal cephalic vein that enters the axillary vein (cephalic arch) is a common site of stenosis in patients with upper extremity arteriovenous fistulas for hemodialysis (HD). In this study, we present the outcomes of a series of cephalic vein transposition, to determine its utility in the setting of refractory arch stenosis. Methods We conducted a retrospective review of patients undergoing cephalic vein transposition to manage refractory cephalic arch stenosis from January 1, 2008 to August 31, 2015. Demographics, past medical history, access history of the patients as well as procedural details of the surgery to the stenotic segment, patency of the access, and the need for subsequent interventions were recorded. Results Twenty-three patients underwent a cephalic vein transposition during the study period. The patients undergoing cephalic transposition had their current access for an average of 3.0 ± 2.6 years and had an average of 2.3 ± 0.9 interventions on the access prior to the surgery. Complications from the surgery were uncommon (8.7%) and no patient required a temporary tunneled dialysis catheter. The re-intervention rate was 0.2 ± 0.2 interventions per patient per year. At two years, primary patency was 70.9% and cumulative patency was 94.7% for the patients with cephalic transposition. Conclusions Cephalic vein transposition is safe and effective treatment for cephalic arch stenosis without interrupting utilization of the access. The surgical approach to stenosis of the proximal cephalic vein is effective, requires minimal re-interventions, and should be considered for isolated, refractory cephalic arch stenosis in mature arteriovenous fistulas.
Resolution of reactive angioendotheliomatosis in an arteriovenous fistula with innominate vein angioplasty
Authors: Vacharathit Voranaddha , Billings Steven D. , Kirksey Lee 
Published: December 2017

Introduction: Arteriovenous fistulae (AVF)-associated reactive angioendotheliomatosis (RAE) is a very rare entity (three previously reported cases in the literature) that can manifest as extremity wounds. RAE’s etiopathology is unknown. Case description: We report a case of severe limb-threatening upper extremity wound with pathology-proven RAE. This lesion was previously refractory to standard wound care. There was no evidence of limb ischemia or steal syndrome, previously deemed to be the underlying cause of AVF-associated RAE in other reports. Conclusions: Successful endovascular treatment of an ipsilateral innominate vein stenosis led to reduction of venous hypertension, resolution of associated arm edema, and subsequent wound healing. We therefore propose that venous engorgement and hypertension from central venous stenosis is the likely underlying cause for AVF-associated RAE. If this rare entity is encountered in the setting of AVF, there is utility in treating the wound as a sentinel lesion and venography should be conducted to rule out central venous pathology. Vascular intervention complements aggressive local wound management and biopsy is requisite for prompt diagnosis.
Viabahn stent for hemodialysis shunt: efficacy, long segment recanalization and prognostic factors for reintervention
Authors: Salsano Giancarlo , Trezzi Matteo , Barattini Matteo , Puccianti Franca , Romano Nicola , Zattera Tito , Chiappini Nadia , Londrino Francesco , Rolla Davide , Stefanini Teseo 
Published: December 2017

Introduction: The study evaluated the Heparin Bioactive Surface (HBS) Viabahn Stent (W.L. Gore & Associates, Flagstaff, Arizona) efficacy in the maintenance or re-establishment of hemodialysis. Materials and methods: Fifty HBS Viabahn stents deployed in 37 consecutive patients with hemodialysis dysfunction from January 2008 to May 2016 were evaluated in a single-institution retrospective review. Outcomes were stent patency intended as primary circuit patency (PP), assisted primary patency (APP), target lesion primary patency (TLPP) and secondary patency (SP). Moreover, the risk factor analysis for hemodialysis dysfunction that required reintervention was performed. A subgroup analysis was conducted to assess patency of Viabahn stent to treat peripheral venous long segment obstruction (LSO). Results: Overall Kaplan-Meyer PPs were 60% at 12 months and 42% at 24 months. Overall TLPP estimated rates were 68% and 49% at 12 and 24 months, respectively. The corresponding SP rates were 85% and 78% at the same period. Estimated PP rates at 12 and 24 months for stent placement after peripheral venous long segment recanalization procedure were 53% and 31%, respectively. Corresponding SP rates were 82% and 68%, respectively. The APP rates were 79% at 12 months and 61% at 24 months. Female sex, access age and thrombosis were associated with reduced primary patency. Conclusions: Considering the high rates of PP, TLPP, APP and SP, Viabahn stents have been proven effective in maintaining or re-establishing the hemodialysis access. Moreover, stent placement after recanalization of LSO of venous out-flow represented a valid approach to rescue a dysfunctional fistula that would otherwise be abandoned.
Bilateral parotid gland metastases from gastric signet-ring cell carcinoma
Authors: Nichetti Federico , Morano Federica , Fabbri Alessandra , de Braud Filippo , Di Bartolomeo Maria 
Published: December 2017

Introduction: Signet-ring cell (SRC) carcinoma is a common subtype of gastric adenocarcinoma associated with poor prognosis. Metastatic involvement of the parotid gland has been reported in gastric cancer patients, but never bilaterally nor in association with the SRC histotype. Here, we report the first case and a brief review of the literature. Case description: A 47-year-old woman was referred to our center for a signet-ring gastric carcinoma with synchronous hepatic and peritoneal metastases. After 3 lines of chemotherapy, the patient reported a progressive bilateral enlargement in the periauricolar area. An ultrasound of the salivary glands and a fine needle biopsy were diagnostic for parotid metastases of gastric origin. In the literature, only 3 cases of parotid gland metastases arising from gastric cancer are described – none with a feature of SRC carcinoma. Conclusions: To the best of our knowledge, this is the first report of gastric SRC carcinoma with bilateral parotid metastases. This case highlights the importance of considering a parotid enlargement as a possible sign of disease progression in a patient with gastric cancer. Fine-needle biopsy and immunocytochemistry are essential in establishing the origin of the secondary lesion.
Biliary tract rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Associazione Italiana Ematologia Oncologia Pediatrica
Authors: Perruccio Katia , Cecinati Valerio , Scagnellato Angela , Provenzi Massimo , Milano Giuseppe Maria , Basso Eleonora , Manzitti Carla , Cecchetto Giovanni , Alaggio Rita , Di Martino Martina , Schiavetti Amalia , Melchionda Fraia , Affinita Maria Carmen , Chiaravalli Stefano , Miglionico Lucia , Balter Rita , Tamburini Angela , Bisogno Gianni , Ferrari Andrea 
Published: December 2017

Introduction: Rhabdomyosarcoma is a soft tissue malignant musculoskeletal tumor frequent in children. Biliary duct localization is extremely rare, but it is the most common cause of malignant obstructive jaundice in pediatric patients. Methods: This report describes a series of 10 patients under 18 years of age with biliary tract rhabdomyosarcoma who were enrolled, from 1979 to 2004, in 3 consecutive Italian pediatric cooperative protocols that had been drawn up by the Soft Tissue Sarcoma Committee of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP). Results: Considering initial and delayed surgery, tumor resection was achieved in 7 cases, 3 complete with free margins (2 liver transplants) and 4 with microscopic residual disease. Chemotherapy was given to all patients and radiotherapy to 3. At present, 5 patients survive in complete remission 90-200 months after diagnosis while 4 died of disease progression or relapse and 1 of liver transplant-related complications. Conclusions: Better outcomes in this series were associated with the feasibility of conservative surgery due to the favorable location of the tumor, in particular in the common bile duct. Chemotherapy and radiotherapy might obviate the need for demolitive surgery or liver transplant, which were linked to worse outcomes in our series.
Can pancreatic cancer be detected by adrenomedullin in patients with new-onset diabetes? The PaCANOD cohort study protocol
Authors: Antolino Laura , Rocca Mara La , Todde Federico , Catarinozzi Elena , Aurello Paolo , Bollanti Lucilla , Ramacciato Giovanni , D’Angelo Francesco 
Published: December 2017

Introduction: Pancreatic cancer is a leading cause of cancer-related death. Its diagnosis is often delayed and patients are frequently found to have unresectable disease. Patients diagnosed with new-onset diabetes have an 8-fold risk of harboring pancreatic cancer. Adrenomedullin has been claimed to mediate diabetes in pancreatic cancer. New screening tools are needed to develop an early diagnosis protocol. Methods: Patients aged 45-75 years within 2 years of first fulfilling the ADA criteria for diabetes will be prospectively enrolled in this study. Sepsis, renal failure, microangiopathy, pregnancy, acute heart failure and previous malignancies will be considered as exclusion criteria. Results: 440 patients diagnosed with new-onset diabetes will be enrolled and divided into 2 groups: one with high adrenomedullin levels and one with low adrenomedullin levels. Patients will undergo 3 years’ follow-up to detect pancreatic cancer development. Conclusions: Identifying a marker for pancreatic cancer among high-risk patients such as new-onset diabetics might lead to the identification of a subpopulation needing to be screened in order to enable early diagnosis and treatment of a highly lethal tumor. Trial registration: This trial was registered at ClinicalTrials.gov on May 25, 2015 under registration number NCT02456051.
Risk prediction model for disease-free survival in women with early-stage cervical cancers following postoperative (chemo)radiotherapy
Authors: Je Hyoung Uk , Han Seungbong , Kim Young Seok , Nam Joo-Hyun , Park Won , Song Sanghyuk , Song Changhoon , Kim Jin Hee , Kim Juree , Yoon Won Sup , Yoon Mee Sun , Choi Hwa Jin , Kim Joo-Young 
Published: December 2017

Purpose: To investigate disease-free survival (DFS) and prognostic factors following the administration of postoperative (chemo)radiotherapy in patients with early-stage cervical cancers. Methods: The medical records of 1,069 patients from 10 participating institutions were reviewed. Statistically and clinically established factors were considered as candidates for constructing the prediction model. This model was validated, using bootstrapping to correct for optimistic bias. Results: The 5-year DFS rate was 81.1%, with a median follow-up period of 59.6 months. The statistically significant prognostic factors were as follows: pelvic lymph node metastasis, histologic type, parametrial invasion, lymphovascular space invasion, and tumor size. The nomogram for DFS was constructed, and it demonstrated a good discrimination performance, with an internally validated concordance index of 0.72. Conclusions: Our predictive model exhibited accurate predictions and may be useful in designing clinical trials to study if further chemotherapy can reduce the recurrence of disease in high-risk patients.
Impact of coexistent adenomyosis on outcomes of patients with endometrioid endometrial cancer: a propensity score-matched analysis
Authors: Aydin Hulya Ayik , Toptas Tayfun , Bozkurt Selen , Pestereli Elif , Simsek Tayup 
Published: December 2017

Purpose: Despite the common occurrence of adenomyosis in endometrial cancer (EC), there is a paucity and conflict in the literature regarding its impact on outcomes of patients. We sought to compare outcomes of patients with endometrioid type EC with or without adenomyosis. Methods: A total of 314 patients were included in the analysis. Patients were divided into 2 groups according to the presence or absence of adenomyosis. Adenomyosis was identified in 79 patients (25.1%). A propensity score-matched comparison (1:1) was carried out to minimize selection biases. The propensity score was developed through multivariable logistic regression model including age, stage, and tumor grade as covariates. After performing propensity score matching, 70 patients from each group were successfully matched. Primary outcome of the study was disease-free survival (DFS), and the secondary outcomes were overall survival (OS) and disease-specific survival (DSS). Results: Median follow-up time was 61 months for the adenomyosis positive group and 76 months for the adenomyosis negative group. There were no statistically significant differences in 3- and 5-year DFS, OS, and DSS rates between the 2 groups. Five-year DFS was 92% vs 88% (hazard ratio [HR] 1.54 [0.56-4.27]; p = 0.404), 5-year OS was 94% vs 92% (HR 1.60 [0.49-5.26]; p = 0.441), and 5-year DSS was 94% vs 96% (HR 2.51 [0.46-13.71]; p = 0.290) for patients with and without adenomyosis, respectively. Conclusions: Coexistent adenomyosis in EC is not a prognostic factor and does not impact survival outcomes.