bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlated mid-infrared and X-ray outbursts in black hole X-ray binaries: a new route to discovery in infrared surveys
Authors: John Chris , De Kishalay , Lucchini Matteo , Behar Ehud , Kara Erin , MacLeod Morgan , Panagiotou Christos , Wang Jingyi 
Published: October 2024

ABSTRACT
The mid-infrared (MIR; $\lambda \simeq 3\!\!-\!\!10\ \mu \mathrm{ m}$) bands offer a unique window into understanding accretion and jet formation in Galactic black hole X-ray binaries (BHXRBs). Although difficult to observe from the ground, the Near-Earth Object Wide-field Infrared Survey Explorer (NEOWISE) survey offers an excellent data set to study MIR variability when combined with contemporaneous X-ray data from Monitor of All-sky X-ray Image (MAXI) mission over an $\approx\!\! 15$ yr baseline. Using a new difference imaging pipeline for NEOWISE data, we present the first systematic MIR study of BHXRB outbursts. Analysing a sample of 16 sources, we show variability trends wherein (i) the MIR bands are dominated by jet emission during the hard states, constraining the electron power spectrum index ($p\approx 1\!\!-\!\!4$) in the optically thin regime and indicating emitting regions of few $10\times$ gravitational radii when evolving towards a flat spectrum, (ii) the MIR luminosity ($L_{\mathrm{ IR}}$) scales as $L_{\mathrm{ IR}} \propto L_\mathrm{ X}^{0.82\pm 0.12}$ with the $2\!\!-\!\!10$ keV X-ray luminosity ($L_\mathrm{ X}$) in the hard state, consistent with a jet, and (iii) thermal disc emission dominates the soft states as the jet switches off and suppresses ($\gtrsim\!\! 10\times$) the MIR emission into an inverted spectrum (spectral index $\alpha \approx -1$). We highlight ‘mini’ outbursts detected in NEOWISE (including two previously unreported episodes of MAXI J1828−249 from September 2015 and September 2016) but missed in MAXI due to their faint fluxes’ confusion, exhibiting MIR colours suggestive of thermal disc emission. We highlight that upcoming infrared surveys and the Rubin observatory will be powerful discovery engines for the distinctively large-amplitude and long-lived outbursts of BHXRBs, as an independent discovery route to X-ray monitors.
Diagnosis and Management of Thoracolumbar Spinal Disorders Presenting as Cardiac, Gastrointestinal, and Other False Pain Syndromes
Authors: Brown Nolan J. , Kuo Cathleen , Pennington Zach , Zhang Angie , Choi Ashley E. , Chan Andrew K. , Shahrestani Shane , Bui Nicholas E. , Hatter Matthew J. , Camino-Willhuber Gaston , Pham Martin H. , Oh Michael Y. 
Published: October 2024

Summary of Background Data:
Although pseudoangina is most commonly caused by cervical disc herniation, several cases have been described where thoracic herniation produced symptoms of pseudoangina. If thoracic herniation can produce angina-like pain, then it is important to consider whether pathology of the thoracolumbar spine, in general, can trigger false pain syndromes distinct from pseudoangina.

Objective:
We seek to provide the most comprehensive study regarding the diagnosis and treatment of spinal conditions causing false pain syndromes.

Study Design:
Systematic review of the current literature using PRISMA 2020 recommendations.

Methods:
We queried the literature and systematically selected relevant studies according to PRISMA guidelines.

Results:
Across 22 selected studies, the sample size was 30 patients, and a total of 26 met the criteria for statistical analysis. Seven (26.9%) of these patients presented with a chief complaint of pseudoangina resulting from thoracic disc herniation. 73.1% (19/26) of patients exhibited pain mimicking visceral origin. Overall, 13/19 (68.4%) patients exhibited thoracic spine disease only and 4/19 (21.1%) patients were affected at lumbar levels only, while 2 (10.5%) patients exhibited thoracolumbar herniation. Presentations included abdominal pain (11/19) mimicking appendicitis or pancreatitis, flank pain mimicking renal colic (8/19), and 2 cases of scrotal pain/orchalgia. Symptom durations ranged from acute (<24 h) to 7 years. Treatments were reported for 18/19 patients and all treated patients reported alleviated pain. Seven out of 18 patients were managed conservatively while 11/18 were treated surgically. Misdiagnosis resulted in unnecessary surgery (pancreaticojejunostomy) or other invasive procedures.

Conclusions:
In spinal disorders manifesting with atypical pain syndromes, delay in proper diagnosis and unnecessary treatments can, unfortunately, cause prolonged patient suffering and increased cost of health care. As a result, some have proposed that spinal screening should be incorporated into clinical examinations involving false pain syndromes.
Risk Factors for Increased Opioid Use During Postoperative Intensive Care
Authors: Guichard Lauriane , Engoren Milo C. , Li Yi-Ju , Sigakis Matthew J. , An Xinming , Brummett Chad M. , Mauck Matthew C. , Raghunathan Karthik , Clauw Daniel J. , Krishnamoorthy Vijay 
Published: October 2024

IMPORTANCE:
In the ICU, opioids treat pain and improve ventilator tolerance as part of an analgosedation approach. Identifying predictors of opioid consumption during the ICU course might highlight actionable items to reduce opioid consumption.

OBJECTIVES:
To identify risk factors for opioid use during a postoperative ICU course.

DESIGN, SETTING, AND PARTICIPANTS:
Patients enrolled in the Michigan Genomics Initiative single-center prospective observational cohort study completed baseline preoperative sociodemographic and mental/physical health questionnaires and provided blood samples for genetic analysis. Included patients were 18 years old and older, admitted to ICU postoperatively, and received opioids postoperatively.

MAIN OUTCOMES AND MEASURES:
The primary outcome was ICU mean daily oral morphine equivalent (OME) use. The association between OME and phenotypic risk factors and genetic variants previously associated with pain were analyzed through univariable and multivariable linear regression models.

RESULTS:
The cohort consisted of 1865 mixed-surgical patients with mean age of 56 years (sd, 15 yr). Preoperative opioid users were more likely to continue to receive opioids throughout their ICU stay than opioid-naive patients. OME (log10 scale) was most strongly associated with ICU mechanical ventilation (β = 0.27; 95% CI, 0.15–0.38; p < 0.0001; effect size 1.85 for receiving > 24 hours of mechanical ventilation), preoperative opioid use (β = 0.22; 95% CI, 0.16–0.29; p < 0.0001; effect size 1.67 for receiving preoperative opioids), major surgery (β = 0.21; 95% CI, 0.12–0.30; p < 0.0001; effect size 1.62 compared with minor surgery), and current/former illicit drug use (β = 0.12; 95% CI, 0.01–0.23; p = 0.04; effect size 1.30 for drug use). Younger age, centralized pain, and longer anesthetic duration were also significantly associated with OME but with smaller effect sizes. Selected genetic variants (FKBP5, COMT, and OPRM1) were not associated with OME use.

CONCLUSIONS AND RELEVANCE:
Mechanical ventilation and preoperative opioids were the strongest risk factors for postoperative ICU opioid consumption, whereas psychologic factors and genetic variants were not associated.
Travel Distances for Interhospital Transfers of Critically Ill Children: A Geospatial Analysis
Authors: Joseph Allan M. , Horvat Christopher M. , Davis Billie S. , Kahn Jeremy M. 
Published: October 2024

IMPORTANCE:
The U.S. pediatric acute care system has become more centralized, placing increasing importance on interhospital transfers.

OBJECTIVES:
We conducted a geospatial analysis of critically ill children undergoing interfacility transfer with a specific focus on understanding travel distances between the patient’s residence and the hospitals in which they receive care.

DESIGN, SETTING, AND PARTICIPANTS:
Retrospective geospatial analysis using five U.S. state-level administrative databases; four states observed from 2016 to 2019 and one state from 2018 to 2019. Participants included 10,665 children who experienced 11,713 episodes of critical illness involving transfer between two hospitals.

MAIN OUTCOMES AND MEASURES:
Travel distances and the incidence of “potentially suboptimal triage,” in which patients were transferred to a second hospital less than five miles further from their residence than the first hospital.

RESULTS:
Patients typically present to hospitals near their residence (median distance from residence to first hospital, 4.2 miles; interquartile range [IQR], 1.8–9.6 miles). Transfer distances are relatively large (median distance between hospitals, 28.9 miles; IQR, 11.2–53.2 miles), taking patients relatively far away from their residences (median distance from residence to second hospital, 30.1 miles; IQR, 12.2–54.9 miles). Potentially suboptimal triage was frequent: 24.2 percent of patients were transferred to a hospital less than five miles further away from their residence than the first hospital. Potentially suboptimal triage was most common in children living in urban counties, and became less common with increasing medical complexity.

CONCLUSIONS AND RELEVANCE:
The current pediatric critical care system is organized in a hub-and-spoke model, which requires large travel distances for some patients. Some transfers might be prevented by more efficient prehospital triage. Current transfer patterns suggest the choice of initial hospital is influenced by geography as well as by attempts to match hospital resources with perceived patient needs.
Reading aloud compared with positive expiratory pressure after abdominal surgery. a randomized controlled trial
Authors: Holmgren Erik , Spyckerelle Iris , Hultin Magnus , Nylén Fredrik , Ottander Ulrika , Sahlin Carin , Svensson Johan , Fagerlund Malin Jonsson , Franklin Karl A. 
Published: October 2024

Background:
Without evidence, positive expiratory pressure therapy is a part of rehabilitation worldwide to prevent postoperative hypoxia. Reading aloud could be used as an alternative therapy as lung volumes increases while speaking. We aimed to investigate whether reading aloud is superior to positive expiratory pressure therapy for improving oxygen saturation after abdominal surgery.

Material and Methods:
This crossover randomized controlled trial compared reading a text aloud with positive expiratory pressure therapy in patients on postoperative day 1 or 2 after upper gastrointestinal, colorectal, urological, or gynecological abdominal surgery at Umeå University Hospital, Sweden. The primary outcome was the change in peripheral oxygen saturation compared with baseline at 7 min after the intervention. The secondary outcome was transcutaneous carbon dioxide partial pressure change.

Results:
This study included 50 patients of which 48 patients were analyzed. Peripheral oxygen saturation rapidly decreased to minimum values below baseline immediately after both interventions and then increased to values above baseline after reading aloud (1%, 95% confidence interval 0.2% to 1%, P = 0.004), but not after positive expiratory pressure therapy (−0.2%, 95% confidence interval −1% to 0.4%, P = 0.436). The difference in oxygen saturation was 1% (95% confidence interval 0.1% to 2%, P = 0.039) at 7 min after termination of the interventions. The interventions reduced transcutaneous carbon dioxide partial pressure by similar amounts.

Conclusions:
This trial adds to the evidence against the use of positive expiratory pressure therapy after abdominal surgery. It is even slightly better to read aloud.
A Novel Approach for Improving Midface Aesthetics: A Pilot Study
Authors: Yamamoto Koji 
Published: October 2024

Background:
Asian individuals often seek solutions to address midface depression and enhance nasal alar base morphology to achieve Western facial aesthetics. Current treatment options, including injections and invasive procedures, have limited efficacy and safety. To address these challenges, we introduced the “modified A-10 surgery,” which integrates the Point A-Koji method, titanium plates, and artificial dermis insertion.

Methods:
The efficacy of the modified A-10 surgery was illustrated using a case study of a 22-year-old woman. Surgical planning was based on dental cone-beam computed tomography data, with lateral cephalometric radiographs used to determine the titanium plate dimensions. The surgery involved customized plate alignment, fixation, and artificial dermis insertion.

Results:
The modified A-10 surgery substantially improved facial aesthetics and structural parameters. Facial convexity increased from 15.5 degrees to 23.2 degrees, enhancing the 3-dimensionality. The nasolabial angle shifted from 91.9 degrees to 110.2 degrees, achieving the desired mouth projection. Other measurements, such as the E-line to the lower lip and the distance from point A to the subnasal point, contributed to refined aesthetics. The nasal alar base thickness increased by 2.2 mm (19.5%), correcting the depression.

Conclusions:
The modified A-10 surgery represents a minimally invasive and comprehensive solution for midface depression and nasal alar base enhancement. By combining the Point A-Koji method, titanium plates, and artificial dermis insertion, this surgery successfully achieved improved facial aesthetics and contours. The results validate its potential as a long-term solution, with implications for antiaging interventions and promising avenues for future research.
VISUAL ACUITY LOSS AFTER VITRECTOMY FOR EPIRETINAL MEMBRANE IN EYES WITH GLAUCOMA
Authors: Higashide Tomomi , Udagawa Sachiko , Yamashita Yoko , Tsuchiya Shunsuke , Okuda Tetsuhiko , Kadonosono Kazuaki , Sugiyama Kazuhisa 
Published: October 2024

Purpose:
To investigate the incidence and predictors of visual acuity loss after surgery for epiretinal membrane in glaucomatous eyes.

Methods:
A prospective cohort study examining visual acuity and central visual fields (VFs, Humphrey 10-2) at baseline and 3, 6, and 12 months after vitrectomy with internal limiting membrane peeling for epiretinal membrane in the glaucoma (47 eyes of 43 patients) and control (46 eyes of 46 patients) groups. Visual acuity and VF tests were repeated for ≥1.5 years only for the glaucoma group. Factors associated with substantial visual acuity loss (>0.2 logarithm of the minimal angle of resolution [approximately >2 lines on the Snellen chart] from baseline) were determined using a Cox proportional hazards model.

Results:
Until 1 year postoperatively, no substantial visual acuity loss occurred and postoperative visual acuity improved significantly and similarly in both groups (P < 0.001 vs. baseline, P > 0.15 between 2 groups). Substantial visual acuity loss occurred in 8 eyes (17%) with glaucoma ≥1.5 years postoperatively, which was associated with worse preoperative VF mean deviation and 1-year mean decrease in postoperative VF mean deviation (hazard ratio = 0.83–0.72; P = 0.018, <0.001, respectively).

Conclusion:
Substantial visual acuity loss occurred long after epiretinal membrane surgery in eyes with glaucoma, which was associated with worse preoperative central VFs and greater central VF deterioration during the first postoperative year.
Perceived Susceptibility to and Severity of Cardiovascular Disease Is Associated With Intent to Change Behavior Among Women 25–55 Years Old
Authors: Rountree Lauren , Fukuoka Yoshimi , Sagae Kenji , Zhang Jingwen , Pike Nancy , Brecht Mary-Lynn , Rezk-Hanna Mary , DeVon Holli A. 
Published: October 2024

Background
Risk factors for cardiovascular disease (CVD) among young and middle-aged women have increased, whereas CVD knowledge and awareness remain low.

Aims
The objective of this study was to describe the relationship between the stage of behavior change and awareness, knowledge, and perceptions of CVD among women 25–55 years and identify predictors of the stage of behavior change.

Methods
A cross-sectional online survey of women ages 25–55 years living in the United States was conducted. Awareness was measured with the question “What is the leading cause of death for women in the United States?” Knowledge, perceptions, and the stage of behavior change were measured with the Heart Disease Fact Questionnaire, Health Beliefs Related to CVD, and Precaution Adoption Process Model instruments, respectively. Chi-square and t tests were used to determine differences between awareness, knowledge, and perceptions based on the stage of behavior change. Multiple logistic regression was used to evaluate the relationship between the stage of behavior change and awareness, knowledge, and perceptions.

Results
A total of 149 primarily minority women (n = 105) were included (mean age = 37.15 ± 7.86 years). The perception of CVD susceptibility was associated with increased intention to change behavior (odds ratio, 1.247; 95% confidence interval, 1.101–1.414; P < .001). The perception of CVD severity was associated with reduced intention to change behavior (odds ratio, 0.809; P = .004).

Conclusion
Women who believed they were susceptible to CVD and did not perceive CVD as severe were more likely to report intent to change behavior, suggesting perception of CVD risk is more important than awareness or knowledge. Addressing misperceptions may be a strategy for primary risk reduction.
Functional Capacity, Functional Performance, and Symptoms in People With Heart Failure
Authors: Wang Zequan , Redeker Nancy S. , Tocchi Christine , Kim Kyounghae , Conley Samantha , Chyun Deborah 
Published: October 2024

Background
Heart failure (HF) is a clinical syndrome that has a negative effect on functional status, a multidimensional concept characterizing one's ability to provide for the necessities of life. Symptoms might be associated with different aspects of functional status in HF. However, the terms functional capacity and performance have been misused interchangeably, and no previous review has focused on the extent to which symptoms contribute to functional capacity and performance among people with HF.

Objective
The aim of this study was to comprehensively review and synthesize the existing literature on the relationship between symptoms, functional capacity, and functional performance in people with HF.

Methods
We conducted an integrated review of observational studies in which authors examined the relationship between at least 1 symptom and at least 1 aspect of functional capacity or performance in people with HF 18 years or older. The Joanna Briggs Institute's critical appraisal tools were used to analyze the quality of studies.

Results
We included 23 studies with 7219 participants and an age range of 40 to 86 years. Fifteen symptom measures were used to measure dyspnea, fatigue, pain, insomnia symptoms, depressive symptoms, and anxiety symptoms. Three functional capacity measures were assessed in 9 studies, and 7 functional performance measures were assessed in 17 studies. As often measured with the Six-Minute Walk Test, functional capacity was inversely associated with pain/discomfort, insomnia symptoms, and psychological symptoms. Functional performance, often measured by the New York Heart Association functional class and Medical Outcome Scale Short Form 36, was associated with sleep difficulties, fatigue, depressive symptoms, and anxiety. Four studies combined functional capacity and performance measures to elicit functional status. Depressive symptoms, fatigue, pain, and insomnia symptoms are associated with decreased functional performance and capacity.

Conclusions and Clinical Implications
Commonly, symptoms experienced in HF are associated with declining functional status. However, this finding depends on the measures or metrics used to assess symptoms, functional capacity, and performance. The observed dissimilarities in the relationship between symptoms and functional capacity and performance highlight the conceptual distinctions, suggesting that authors of future studies should judiciously select appropriate dimensions and measures of functional status based on the study's purposes, design, and available resource.
Effect of a colorectal bundle in an entire healthcare region in Switzerland: results from a prospective cohort study (EvaCol study)
Authors: Wiesler Benjamin , Rosenberg Robert , Galli Raffaele , Metzger Jürg , Worni Mathias , Henschel Mark , Hartel Mark , Nebiker Christian , Viehl Carsten T. , Müller Alexandra , Eisner Lukas , Pabst Martina , Zingg Urs , Stimpfle Daniel , Müller Beat P. , von Flüe Markus , Peterli Ralph , Werlen Laura , Zuber Markus , Gass Jörn-Markus , von Strauss und Torney Marco 
Published: October 2024

Introduction:
Standardization has the potential to serve as a measure to mitigate complication rates. The objective was to assess the impact of standardization by implementing a colorectal bundle (CB), which comprises nine elements, on the complication rates in left-sided colorectal resections.

Patients and methods:
This prospective, multicentre, observational, cohort trial was conducted in Switzerland at nine participating hospitals. During the control period, each patient was treated in accordance with the local standard protocol at their respective hospital. In the CB period, all patients were treated in accordance with the CB. The primary endpoint was the Comprehensive Complication Index (CCI) at 30 days.

Results:
A total of 1141 patients were included (723 in the No CB group and 418 in the CB group). The median age was 66 years, and 50.6% were female. Median CCI before and after CB implementation was 0.0 (interquartile range [IQR]: 0.0–20.9). A hurdle model approach was used for the analysis. The CB was not associated with the presence or severity of complications. Older age (odds ratio [OR] 1.02, 95% CI: 1.00–1.03), surgery for malignancy (OR 1.34, 95% CI: 1.01–1.92), emergency surgery (OR 2.19, 95% CI: 1.31–3.41), elevated nutritional risk score (OR 1.13, 95% CI: 1.01–1.24), and BMI (OR 1.04, 95% CI: 1.00–1.06) were associated with higher odds of postoperative complications. In a supplementary per-protocol analysis, for each additional item of the CB fulfilled, the odds of anastomotic leakage (AL) were 24% lower (OR 0.76, 95% CI: 0.64–0.93).

Conclusions:
Dedicated teams can establish high-quality colorectal services in a network of hospitals with a joint standard. The study can serve as a model for other healthcare settings to conduct and implement quality improvement programs. The consistent implementation of the CB items can reduce the occurrence of AL.