bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between trace elements and cognitive function among hemodialysis patients in Turkey
Authors: Oruc Meric , Asan Furkan , Mercan Selda , Kose Sennur , Kirpinar Mehmet Murat , Poyraz Burc Cagri , Trabulus Sinan , Savrun Feray Karaali , Altiparmak Mehmet Riza 
Published: October 2024

AbstractIntroductionCognitive impairment is common among patients with hemodialysis. Hemodialysis patients have theoretical risks for both deficiency and accumulation of trace elements. We aimed to investigate the relationship between cognitive dysfunction and whole blood levels of trace elements in hemodialysis patients. We also aimed to examine the effect of baseline trace element status and cognitive dysfunction on mortality.MethodsMaintenance hemodialysis patients and age‐and sex‐matched controls were included. The whole blood levels of trace elements were measured by inductively coupled plasma mass spectrometry. Cognitive impairment was defined as a score of ≤24 points on the Montreal Cognitive Assessment test. Executive dysfunction was also defined as Trails A score of more than 75 s and Trails B score of more than 180 s.FindingsForty‐two patients and 35 controls were included. Cognitive impairment was detected in 69% of the patients and 45.7% of the controls (p = 0.039). Cognitively impaired patients had lower education years (p = 0.003) and higher whole blood levels of manganese (Mn) and lead (Pb) (p = 0.026, p = 0.019, respectively) compared to patients without cognitive impairment. Mn levels were also found statistically higher in patients with executive dysfunction compared to patients without executive dysfunction (p = 0.005). Lower education years and higher Pb levels were independent risk factors for cognitive impairment in hemodialysis patients (odds ratio [OR] 0.589 [95% confidence interval, CI 0.400–0.866, p = 0.007] and OR 1.047 [95% CI 1.001–1.096, p = 0.047, respectively]).DiscussionCognitive impairment, especially impaired executive function, is common among patients with hemodialysis patients. Cognitive impairment is not found to be associated in cross‐sectional analysis with several modifiable end‐stage renal disease‐ and dialysis‐associated factors. The accumulation of trace elements especially Mn and Pb might exacerbate the cognitive dysfunction in hemodialysis patients.
Perceived Impact of Healthcare Relationships and Interactions on Parental Experiences of Prenatal Diagnosis and Termination of Pregnancy for Foetal Anomaly on the Island of Ireland
Authors: Heaney Suzanne , Tomlinson Mark , Aventin Áine 
Published: October 2024

ABSTRACTObjectiveThe aim of this study was to explore parents' experiences of their relationships and interactions with healthcare professionals (HCPs) during care related to prenatal diagnosis and termination of pregnancy for foetal anomaly (TOPFA).MethodsA qualitative approach was used. Participants included 33 parents (23 women and 10 men) from Northern Ireland (n = 11) and Ireland (n = 22) who had a TOPFA. Data collection methods included semi‐structured interviews and written narrative accounts. Data were analysed using thematic analysis.ResultsFindings confirmed that TOPFA was a traumatic, life‐altering experience for parents, impacting their health and well‐being. The actions, behaviours and words of HCPs impacted how parents perceived and interpreted their healthcare experiences and their access to services and supports. In relation to this, five themes are presented: (1) the importance of compassionate and non‐judgemental care, (2) the value of effective information and communication, (3) the desire for compassionate care for baby and facilitation of memory making, (4) the need for continuity of care and (5) parents' experiences of healthcare relationships during times of legislative change.ConclusionThis research reveals the important role HCPs play in helping parents cope with prenatal testing and TOPFA. Parents who had a positive relationship with an HCP, in which information was communicated effectively and compassionate and non‐judgmental care was provided, felt more supported and more able to accept and adapt to their loss.Patient and Public ContributionAn advisory group composed of parents who had experienced TOPFA and HCPs with experience in caring for such families were involved in the study from the outset, contributing to the design and development of data collection materials, interpretation of the findings and design of dissemination materials.
Interdisciplinary Approach to Consumer Financial Behavior: Developing a Conceptual Framework
Authors: Warchlewska Anna 
Published: October 2024

ABSTRACTThe purpose of this article is to develop a conceptual framework of consumer financial behavior with a multidisciplinary approach. Consumer financial behavior is the subject of research in many scientific disciplines, although it is of greatest interest to economists, sociologists, psychologists, and philosophers. The frailty and still insufficient functionality, as well as the lack of application of the models may result from constantly changing macro and microeconomic factors, changing trends, the impact of generational affiliation, and conceptual‐theoretical inconsistencies. Taking into consideration current attitudes toward understanding consumer financial behavior, a contribution to literature is an attempt to diagnose the components of a functional model for financial behaviors, in particular, the diagnosis of input and output factors in the decision‐making process. The proposed model of consumer financial behavior consists of five elements: type of consumer, type of financial product, motivation, abilities, and opportunities, and the factors determining them may be both economic and noneconomic.
Effectiveness of Mobile Application Disease Self‐Management Programme on Mental Health and Self‐Management of Patients With Hypertension: A Randomised Controlled Trial
Authors: Lee Mei‐Chen , Liu Chuan‐Chieh , Wang Wen‐Hug , Lin Mei‐Hsiang , Liao Pei‐Hung , Chen Meng‐Qi 
Published: October 2024

ABSTRACTBackgroundHypertension is a chronic disease that consumes considerable medical resources.AimThe aim of this study is to evaluate a model able to develop and assess the effectiveness of a mobile application disease self‐management programme regarding mental health and self‐management for patients with hypertension.MethodsA randomised controlled trial and single‐blind random assignment was employed to group the participants. A total of 100 patients were collected from the cardiology clinic of a teaching hospital in Taiwan. There were 50 participants in each group: the mobile application group (experimental group) and the routine care (control group). The primary outcome measures were mental health and self‐management.ResultsThis study discovered that the intervention improved the mental health and self‐management of the experimental group. The results for the experimental group revealed significantly improved effects and outcomes superior to those of the control group.ConclusionsThe study results verified that a mobile application disease self‐management programme could improve the mental health and disease self‐management of patients with hypertension.
Economic Analysis of Falls in a Private Hospital in Southern Brazil—A Case–Control Study
Authors: Gonzalez Victor Antoniazi , Febras Larissa Luma Tomasi , de Lima Cássia Cristina Damásio , Alves Belisa Marin , dos Santos Daniel Teixeira , Souza Mariana Almudi , Carvalho Sidiclei Machado , Rohsig Vania , Pille Arthur , Wolf Jonas , Maccari Juçara Gasparetto , Mutlaq Mohamed Parrini , Nasi Luiz Antônio 
Published: October 2024

ABSTRACTIntroductionIn‐hospital falls represent significant health and economic concerns, but previous studies regarding the economic cost of falls do not account for other cofounders (comorbidities and clinical aspects) in this cost evaluation.AimThe aim of this study is to analyse the cost of in‐hospital falls comparing those who had falls to nonfalls patients while accounting for several risk factors associated with falls.MethodsData were collected from January 2020 to December 2022, in a private hospital in Brazil. The sample was divided into two groups: one with patients who fell and the other with nonfallers on a 1:2 ratio, and these groups were matched to avoid confounding variables.ResultsThe median cost for patients who experienced falls was US$7520.26 compared to US$6144.24 for those without falls (p < 0.01). This trend was especially marked in men aged 20–40 who suffered falls and showed a significantly elevated median cost of US$29 722.02 distinguishing them from those without falls with a median cost of US$1179.48 (p < 0.01).ConclusionHospital falls significantly increase financial costs compared to nonfall cases, irrespective of comorbidities, length of stay or case‐mix variations. The findings recommend a universal precautions approach to fall prevention in hospitals, targeting all hospitalised patients to effectively minimise the economic burden associated with in‐hospital falls.
Nurse Experiences of Caring for Medically Compromised Adolescents With Eating Disorders in General Hospital Environments: A Scoping Review
Authors: Gamlath Inuri , Buchanan‐Hagen Sally , Alexander Louise , Searby Adam 
Published: October 2024

ABSTRACTEating disorders encompass a spectrum of mental health conditions that are characterised by a preoccupation with eating, exercise, body weight or shape. The trajectory of eating disorders can result in hospitalisation for medical complications, such as electrolyte imbalance, extremely low weight and other medical issues that require urgent inpatient attention. Typically, care for adolescents with medically compromised eating disorders occurs in general medical settings, with most care provided by nurses who may or may not have the training and experience to provide quality care for this complex mental health condition. The aim of this scoping review is to examine literature surrounding the experience of nurses caring for adolescents admitted to general medical wards (non‐mental health settings) with medically compromised eating disorders. We used Arksey and O'Malley's (2005) five‐step scoping review process to conduct this review. A systematic search of the literature located 476 relevant papers, and after screening, 10 were included in the final review. Most included papers were qualitative in methodology, with one using a mixed‐methods design. The papers examined in this scoping review found common themes among nurses who were providing care for adolescents with medically compromised eating disorders being cared for in medical wards (non‐mental health settings): a lack of preparation to care for individuals with eating disorders, a high emotional and psychological toll on nurses providing care and a degree of stigma towards adolescents with eating disorders, including a belief that eating disorders were a ‘choice.’ This review indicates that to provide quality and safe care for adolescents with eating disorders admitted to general medical wards, nurses require specialised training. In addition, the care of adolescents with medically compromised eating disorders requires the support of trained mental health nurses, especially where nurses on general medical wards are novice or have limited mental health training. We recommend further research into support structures to prevent burnout and turnover that is prevalent when providing care to individuals with eating disorders.
Incidence and Risk of Coronavirus Disease 2019 Hospitalization Among Unvaccinated Children
Authors: Zerbo Ousseny , Timbol Julius , Hansen John R. , Goddard Kristin , Layefsky Evan , Ross Pat , Fireman Bruce , Nguyen Dao , Greenhow Tara L. , Klein Nicola P. 
Published: October 2024

ABSTRACTObjectivesThe aim of this study is to determine the incidence and risk factors associated with COVID‐19 hospitalization among unvaccinated children.MethodsChildren aged 0– < 18 years, members of Kaiser Permanente Northern California (KPNC), were followed from March 1, 2020, until the earliest occurrence of: chart‐confirmed COVID‐19 hospitalization, disenrollment from KPNC, age 18 years, receipt of COVID‐19 vaccine, death, or study end (December 31, 2022). We calculated the incidence rate of hospitalization by SARS‐CoV‐2 variant period and by age group. We determined risk factors for hospitalization using Poisson regression. We also conducted descriptive analyses of hospitalized cases.ResultsAmong 1,107,799 children, 423 were hospitalized for COVID‐19 during follow‐up. The incidence of hospitalization increased with each new SARS‐CoV‐2 variant and was highest among children aged < 6 months. Among the < 6‐month‐olds, the incidence rate per 100,000 person‐months was 7 during predelta, 13.3 during delta, and 22.4 during omicron. Black (RR = 2.05, 95% CI: 1.33–3.16) and Hispanic children (RR = 1.82, 95% CI: 1.34–2.46) and children with any comorbidities were at high risk of hospitalization (RR = 3.81, 95% CI: 2.94–4.95). Overall, 20.3% of hospitalized children were admitted to an intensive care unit (ICU), but ICU admission was 36.1% among 12– < 18‐year‐olds. The majority of ICU admits (91.8%) had no comorbidities.ConclusionChildren too young to be vaccinated had the highest incidence of COVID‐19 hospitalization, while adolescents had the highest proportion of ICU admissions. To prevent severe disease in children and adolescents, everyone eligible should be vaccinated.
Frequency and Genotype‐Dependence of intrinsic chronotropic insufficiency among patients with congenital long QT syndrome
Authors: Kulkarni Veda K. , Pinsky Alexa M. , Bos J. Martijn , Neves Raquel , Bains Sahej , Giudicessi John R. , Allison Thomas G. , Ackerman Michael J. 
Published: October 2024

AbstractIntroductionLong QT syndrome (LQTS) is a cardiac channelopathy characterized by QT prolongation and a potential for arrhythmic syncope, sudden cardiac arrest or deaths (SCA/SCD). It has been speculated that patients with LQTS might have a primary sinoatrial node (SAN) phenotype of chronotropic insufficiency (CI). This has not been demonstrated convincingly before because of the potentially confounding effects of beta blocker (BB) therapy. Herein, we set out to determine whether untreated patients with LQTS demonstrate intrinsic CI.Methods and ResultsA retrospective review of all treadmill exercise stress tests (TEST) was performed on patients with one of the three most common LQTS genotypes: LQT1, LQT2, and LQT3. For each patient, the first TEST completed while off BB was analyzed. Patients with prior left cardiac sympathetic denervation (LCSD) therapy were excluded. CI was defined as having an age‐ and gender‐predicted peak heart rate (HR) < 85% and/or a predicted HR reserve (HRR) < 80%. Overall, 463 LQTS patients (245 LQT1, 125 LQT2, and 93 LQT3) were included (267 female [58%]; mean age at time of TEST [29 ± 17 years]). Mean % predicted peak HR for all LQTS patients was 87.6% (range 42.9% ‐ 119.1%) and mean % predicted HRR was 80% (range 19.1% ‐ 153%). Overall, half of all LQTS patients (n = 234; 51%) displayed CI; 64% of patients with LQT1 (n = 157), 37% with LQT2 (n = 46), and 33% with LQT3 (n = 31). Patients with LQT1 were most likely to exhibit CI compared to patients with LQT2 (p < .0001) and LQT3 (p < .0001). CI was significantly more common in LQT1 compared to controls (p < .0001), while there was no difference between LQT2 (p = .5) or LQT3 and controls (p > .9). Presence of CI was not a predictor of LQTS‐associated symptoms, BB side effects or likelihood of future breakthrough cardiac events (BCE).ConclusionsPatients with LQTS, particularly LQT1, demonstrate a SAN phenotype of CI. If assessing BB therapy effect by impact on peak HR, the patient's pretreatment peak HR, rather than an age‐ and gender‐predicted maximum HR, should be used.
Medical diagnosis based on artificial intelligence and decision support system in the management of health development
Authors: Chen Kaipeng , Luo Liqing , Tan Ye , Chen Gengcong 
Published: October 2024

AbstractBackgroundMedical diagnosis plays a critical role in our daily lives. Every day, over 10 billion cases of both mental and physical health disorders are diagnosed and reported worldwide. To diagnose these disorders, medical practitioners and health professionals employ various assessment tools. However, these tools often face scrutiny due to their complexity, prompting researchers to increase their experimental parameters to provide accurate justifications. Additionally, it is essential for professionals to properly justify, interpret, and analyse the results from these prediction tools.MethodsThis research paper explores the use of artificial intelligence and advanced analytics in developing Clinical Decision Support Systems (CDSS). These systems are capable of diagnosing and detecting patterns of various medical disorders. Various machine learning algorithms contribute to building these assessment tools, with the Network Pattern Recognition (NEPAR) algorithm being the first to aid in developing CDSS. Over time, researchers have recognised the value of machine learning‐based prediction models in successfully justifying medical diagnoses.ResultsThe proposed CDSS models have demonstrated the ability to diagnose mental disorders with an accuracy of up to 89% using only 28 questions, without requiring human input. For physical health issues, additional parameters are used to enhance the accuracy of CDSS models.ConclusionsConsequently, medical professionals are increasingly relying on these machine learning‐based CDSS models, utilising these tools to improve medical diagnosis and assist in decision‐making. The different cross‐validation values are considered to remove the data biasness.
The impact of climate change anxiety on premenstrual syndrome: A cross‐sectional study
Authors: Yesildere Saglam Havva , Mizrak Sahin Berrak 
Published: October 2024

AbstractObjectiveClimate change is thought to have possible effects on changes in the menstruation process, which covers an important period of time in women's lives. Our study aimed to determine the impact of climate change anxiety on premenstrual syndrome (PMS) in women of reproductive age.MethodsThis is a cross‐sectional study. The research was conducted online using various digital platforms between December 2023 and February 2024. This study was conducted on 456 women of reproductive age. The Personal Information Form, PMS Scale and Eco‐Anxiety Scale were used for the data collection. The level of statistical significance was set at p < 0.05.ResultsThe prevalence of PMS was 44.7%. The average score for the Eco‐Anxiety Scale was 27.28 ± 6.44. A significant majority of participants (81.4%) stated that climate change would affect women's health, and 81.1% thought that they were affected by climate change. The Eco‐Anxiety Scale scores were higher in women with PMS (p < 0.05). The results of the binary logistic regression analysis showed that being affected by climate change (odds ratio [OR] = 2.109, 95% confidence interval [CI] = 1.045–4.259, p = 0.035), age at menarche (OR = 1.249, 95% Cl = 1.073–1.453, p = 0.004) and Eco‐Anxiety Scale scores were significant predictors of PMS (OR = 0.828, 95% Cl = 0.791–0.867, p < 0.001).ConclusionThe results of our study showed that women with PMS had higher Eco‐Anxiety Scale scores. Given the global effects of climate change, it is important to investigate its effects as a risk factor for the emergence of PMS. Furthermore, women's healthcare providers play an important and beneficial role in adapting to a changing climate; these efforts will have long‐term impacts.
Can food sovereignty be institutionalised? Insights from the Cuban experience
Authors: Botella‐Rodríguez Elisa , González‐Esteban Ángel Luis 
Published: October 2024

AbstractCuba stands out among Latin American nations for its efforts to institutionalize food sovereignty (FS) through the promotion of alternative small‐scale farming, making it a prime case study for this model. This paper examines the extent to which Cuba has institutionalized FS and the factors driving this process from an agrarian political economy perspective. Public policies, sustainable practices and key actors—including a ‘partner state’—have advanced agroecology as a core strategy to reduce food imports since the early 1990s. However, other entities, such as the military enterprise Grupo de Administración Empresarial S.A. (GAESA), may be seen as obstacles to this strategy. Whilst these struggles and tensions are not unique to Cuba, the island stands out for its decisive steps in institutionalizing FS. Cuba has achieved significant ‘pockets’ or ‘spaces’ of FS, despite lacking a fully consolidated domestic food system.
Safety and efficacy of tisotumab vedotin with cervical cancers: A systematic review and meta‐analysis
Authors: Mokresh Muhammed Edib , Alomari Omar , Varda Abdullah , Akdag Goncagul , Odabas Hatice 
Published: October 2024

AbstractBackgroundTisotumab vedotin (TV) holds promise for treating recurrence or metastatic cervical cancer (r/mCC), with recent FDA approval for second‐line use in recurrent or metastatic cases. Our research aims to evaluate TV's efficacy and safety in these patients, focusing on overall survival (OS) and progression‐free survival (PFS) outcomes.MethodsWe searched five electronic databases in February 2024, retrieved articles, screened them based on inclusion and exclusion criteria, and assessed their quality. A meta‐analysis of the extracted data was performed and applied a random‐effects model for our analysis.ResultsThe search identified 86 articles, with six meeting the inclusion criteria. Meta‐analysis revealed 80.8% and 48.0% OS at 6 and 12 months, and a 29.9% PFS at 6 months. Combined treatment with carboplatin or pembrolizumab showed 33.0% PFS at 1 year and 15.1% at 2 years. The objective response rate (ORR) was 21.0%, reaching 43.3% with combined treatment. Confirmed disease control rate (CDCR) was 70.0% overall and in combination. The median duration of response (DOR) was 6.1 months, increasing to 9.5 months in combined treatment, with a consistent time to response (TTR) of 1.4 months. Adverse events included ocular issues (conjunctivitis 30.3%, dry eye 18.7%) and common side effects (nausea 38.4%, epistaxis 35.7%).ConclusionThis systematic review and meta‐analysis highlights the potential of TV as a treatment option for r/mCC patients. However, healthcare providers must communicate safety profiles and recommend prophylactic measures for optimal patient outcomes. Further studies, particularly assessing combination treatments, are needed to clarify TV's role in treatment algorithms and improve clinical outcomes.
Trust at the border: identifying risk and assessing credibility on reality television
Authors: SMITH‐KHAN LAURA , PILLER INGRID , TORSH HANNA 
Published: October 2024

AbstractEvery day, officers working at international airports investigate potential risks to state safety and security. But how do they decide who they can trust, and also ensure that the broader public trusts them to conduct this work? This article explores these questions through an examination of the reality television show Border Security: Australia's Front Line. Through critical discourse analysis of a collection of 108 televised airport encounters, we explore the aspects of communication, behaviour, and identity made salient in officers’ evaluations of passengers’ credibility and critically examine the assumptions underlying them. Further, we consider how power and role divisions are implicated in the construction of passenger and officer credibility, both within border encounters and in discourses about them. Our analysis makes a novel contribution to the literature on credibility assessments in intercultural communication, demonstrating how an institutional and social ‘culture of disbelief’ is constructed vis‐à‐vis certain groups through seemingly banal border work.