bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resolving the Ubiquitous Small-Scale Semipermanent Features of the General Ocean Circulation: A Multiplatform Observational Approach
Authors: Wijffels S. E. , Gebbie G. , Robbins P. E. 
Published: October 2024

Abstract
Based on 20 years of Argo and ship/animal-borne/glider hydrographic profile data, we derive a new high-resolution hydrographic Atlas and associated circulation field for the oceans above 2000 dbar. Satellite altimetric observations are used to explicitly regress out eddy noise in the fit, greatly reducing one of the major sources of noise. Geostrophic shears are found from the fitted geopotential anomaly fields. Ekman velocities are estimated using satellite wind stresses. Both Argo trajectory observations at 1000 dbar and surface drifter observations are used to reference geostrophic shears derived from the Atlas hydrography. Surface drifter velocities are analyzed with an additional wind friction term to remove the wind-related flow. Agreement between the surface geostrophic (referenced to Argo trajectories) and drifter-based surface velocity is high at both large scales and mesoscales, lending confidence to the derived geostrophic circulation fields. The Atlas reveals standing mesoscale eddies and meanders in western boundary systems and the braided jet structure of the Antarctic Circumpolar Current. In the interior, the upper-ocean flow consists of a highly baroclinic large-scale Sverdrup flow and smaller-scale (∼200-km width) semizonal jets, which are more barotropic (low vertical shear) and have an average zonal width of around 5000 km. These semizonal jets are globally ubiquitous—found in all basins pole to pole. The many permanent mesoscale features of the mean general circulation contrast with that predicted by theories of the large-scale flow in simplified flat-bottomed domains. The Atlas presents a new opportunity to benchmark modern high-resolution ocean and climate models.

Significance Statement
This study exploits the radical increase in the number of observations of the ocean vertical structure in the past 20 years due to the use of robotic profilers. Combined with satellite observations, this much larger data coverage allows us to uncover the structure of the mean (or time average) ocean and its flow at much smaller horizontal length scales than in the past, like going from a blurry view to a clear one. In this new view, we find small permanent eddies and meanders of major ocean flows and jets around islands and through bathymetric constrictions. We also find ubiquitous semizonal striations throughout the global ocean interior. In the past, these were only seen at the surface, but we now show they reach down to at least 2000 m and comprise a significant part of the ocean’s mean flow field. These features are likely important to how the ocean mixes heat and other important quantities such as oxygen and carbon around Earth.
Near-Surface Particulate Backscattering Observations with Bio-Optical Lagrangian Drifters
Authors: Bellacicco Marco , Pitarch Jaime , Organelli Emanuele , Zoffoli Maria Laura , Concha Javier A. , Falcini Federico , Li Mengyu , Marullo Salvatore , Rio Marie-Helene , Santoleri Rosalia , Centurioni Luca R. 
Published: October 2024

Abstract
Particulate matter concentration is an essential ocean variable (EOV) useful for understanding biogeochemical processes, improving ocean productivity estimates, and constraining coupled physical and biogeochemical numerical models. While direct observations of this parameter are difficult to obtain, the optical backscattering coefficient of marine particles (bbp) can be used as a reliable proxy. However, most in situ multispectral bbp measurements are ship-borne or obtained from moored systems, thus with a limited spatial and temporal coverage. Utilizing Surface Velocity Programme (SVP) drifting buoys with self-contained backscatter sensors designed for extended deployment periods offers a promising solution for collecting data in challenging marine environments. In this study, we presented for the first time the integration of a commercially available, high-frequency, and multispectral optical backscatter sensor into an SVP drifter, the so-called backscatter optical-SVP (BO-SVP) drifter designed to collect bbp measurements near the ocean surface. The bbp measurements obtained by the BO-SVP drifter were reliable over a wide range of environmental conditions, showing a good agreement with independent datasets (relative bias < 10%; relative standard deviation < 36%). The BO-SVP drifter captures the satellite sub- and pixel-scale variability by combining the Lagrangian approach and a high-frequency sampling. This configuration enables the acquisition of measurements across numerous pixels in a single day, enhancing validation activities for ongoing and future satellite products and the quantification of associated uncertainties. The measurements acquired by these platforms can offer valuable insights into particle distribution at fine spatial scales, daily variability, and its relationship with water masses type and ocean dynamics.
How can we do authentic co-construction with autistic secondary pupils?
Authors: Glass Devyn , Gillett Sadie , Yuill Nicola 
Published: October 2024

Purpose of the research: Co-constructed digital storytelling methods have the potential to provide authentic children’s perspectives for planning health and education support. The Our Stories project investigated how this method can be applied with autistic children and young people (CYP). A year-long sub-project supported four autistic CYP in a mainstream secondary school in the UK to create short videos illustrating how they manage their sensory and emotional experiences during the school day. The CYP were supported by a member of the Special Educational Needs and Disabilities team, a specialist autism teacher, a researcher, and filmmakers from a disability-led community interest company. This paper reflects on how we can authentically co-construct digital stories with autistic secondary pupils. Major findings: We identified two broad messages for genuinely participatory research. The first was how the structure of sessions changed, from an initial assumption of imposing structure to achieve the research aims to the negotiation of a messy, more fluid means of working to suit the CYP’s needs and wishes. Second was a change in the intended purpose of the stories, from a product to support reflection and understanding about emotional regulation, to each CYP’s own unfolding of purpose. Conclusion: We draw out general implications for co-construction in participatory research in terms of awareness of how to work with power relations in ways that keep the young person at the centre of analysis, and which recognise the need for space for CYP to construct their own meanings.
Examining the Independent and Interactive Carryover Effects of Cognitive and Physical Exertions on Physical Performance
Authors: Pabla Rahul K. , Graham Jeffrey D. , Watterworth Michael W. B. , La Delfa Nicholas J. 
Published: October 2024

Objective This study compared the effects of prior cognitive, physical, and concurrent exertion on physical performance. Background Fatiguing cognitive and physical exertions have been shown to negatively affect subsequent task performance. However, it is not clearly understood if concurrent physical and cognitive effort may exaggerate the negative carryover effects on physical task performance when compared to cognitive or physical exertion alone. Method Twenty-five participants completed four isometric handgrip endurance trials on different days. The endurance trials were preceded by four, 15-minute experimental manipulations (cognitive, physical, concurrent, control). Electromyography (EMG) and force tracing performance were monitored, with handgrip strength measured pre and post. Subjective ratings of mental and physical fatigue, as well as affect, motivation, and task self-efficacy, were also assessed. Results Handgrip strength decreased following both physical (−14.4% MVC) and concurrent (−12.3% MVC) exertion manipulations, with no changes being observed for the cognitive and control conditions. No differences were observed across conditions for endurance time, EMG, nor tracing performance. When compared to the control conditions, perceptions of mental and physical fatigue were higher following the experimental manipulation. Endurance trial self-efficacy was lower for the mental, physical and concurrent conditions compared to control. Conclusion The concurrent condition resulted in similar decreases in strength as the physical fatigue condition, but otherwise resulted in similar carryover effects on endurance performance across all conditions. Further study is required at higher exposure levels, or for longer exposure durations, to further probe the influence of concurrent physical and cognitive effort on task performance. Application Concurrent cognitive and physical effort resulted in similar physical performance decrements to physical effort alone.
Feasibility of prospective error reporting in home palliative care: A mixed methods study
Authors: Kurahashi Allison M , Kim Grace , Parry Natalie , Hung Vivian , Lokuge Bhadra , Goldman Russell , Bernstein Mark 
Published: October 2024

Background: Prospectively tracking errors can improve patient safety but little is known about how to successfully implement error reporting in a home-based palliative care context. Aim: Explore the feasibility of implementing an error reporting system in a home-based palliative care program in Toronto, Canada, and describe the possible factors that may influence uptake. Design: A convergent mixed-methods approach was used. Participants prospectively documented errors using a novel reporting tool and completed monthly surveys. Following the reporting period, we conducted a semi-structured interview exploring participants’ experiences and perceived factors influencing reporting behaviors. Error, survey, and interview data were analyzed separately, then integrated for comparison. Setting and participants: Thirteen palliative care physicians from a single home-based palliative care organization in Toronto, Canada anonymously reported errors between October 2021 and September 2022. Of these, six participated in the exit interview. Results: Participants reported 195 errors; one-third ( n = 65) involved internal staff or systems. Three themes describe the factors impacting the likelihood of reporting errors: (1) High levels of cognitive burden decreases the likelihood of error reporting; (2) Framing errors as opportunities to learn rather than reason for punishment improves likelihood of error reporting; (3) Knowing that error data will improve patient safety motivates individuals to report errors. Conclusions: Physicians are amenable to error reporting activities so long as data is used to improve patient safety. The collaborative nature of care in a home-based palliative care context may present unique challenges to translating error reporting to improved patient safety.
Prime Factors Influencing the Reluctance Expressed Toward Orthodontic Treatment Among a Tribal Population with No Prior History of Orthodontic Treatments in the Community: A Cross-sectional Study
Authors: Digumarthi Uday Kumar , Prakash R. 
Published: October 2024

Background Perceiving a need for orthodontic treatment is a heuristic process usually conditioned by the interplay between motivational factors and influencing factors in a community with orthodontic awareness and a history of already ongoing or completed orthodontic treatments. Using a verbally assigned index to elicit candid responses, the current study aimed at assessing reluctance toward orthodontic treatment in adolescents with clinically ascertained malocclusion in a community with no prior history of orthodontic treatment. Objectives Tribal adolescents from two regions with clinically ascertained malocclusion but no previous access to orthodontic treatment were evaluated for willingness or reluctance to undergo orthodontic treatment using a verbally assigned Simplified Malocclusion Index for Layperson Evaluation (SMILE index). Methods 2,835 tribal adolescents belonging to the tribal regions of Paderu and Parvathipuram in Andhra Pradesh were questioned to analyze factors related to reluctance toward orthodontic treatment in those with malocclusion. Necessary permission and consent were obtained from the institutional ethical clearance committee, tribal authorities, school authorities, and parents or guardians. Clinical screening employing appropriate infection prevention protocol under natural daylight was used to determine the presence of malocclusion. A verbally assigned SMILE index in the vernacular language of the students with malocclusion was used to record candid responses to analyze possible reluctance toward treatment. Specific reasons for reluctance to undergo treatment were documented and tabulated separately. Pearson chi-square statistical analysis of the data was performed to determine if there was any gender bias. Results At Paderu, of the 68% of the tribal adolescents presenting with malocclusion, the verbally assigned SMILE index revealed that 84.03% of the adolescents were reluctant. The chi-square statistical analysis of the data indicated a gender bias ( X2 (1, N = 2,016) = 35.99, p < .0001). At Parvathipuram, of the 93% of the tribal adolescents presenting with malocclusion, the SMILE index assigned revealed that 93.05% of the adolescents were reluctant. The chi-square statistical analysis of the data indicated a gender bias ( X2 (1, N = 819) = 6.42, p = .11). Conclusion The use of the SMILE index allows for a qualitative analysis of reluctance based on the candid subjective inputs from each individual. The study reveals a high degree of orthodontic awareness among the tribal adolescents, and any reluctance toward orthodontic treatment is mainly related to difficulty in access to treatment.
Factors affecting retention of occupational therapists in adult mental health service: A systematic review with narrative synthesis
Authors: Yan Wenting , Ohlsen Sally , Wood Emily 
Published: October 2024

Introduction: There are over 43,000 occupational therapists across the United Kingdom, with mental health occupational therapists being acknowledged as a main workforce of OT services. However, staff shortages are occurring, and urgent action is needed to retain this important workforce. Methods: The systematic literature search was conducted in the CINAHL, PsycINFO and Scopus databases to identify research literature published since 2008. Due to the heterogeneity of the included studies, a narrative synthesis was utilized. Results: A total of 20 studies (21 papers) were included in the review. Five thematic factors – well-being at work, organizational work environment factors, job resources, supervision and staffing, along with various subtheme factors emerged from the synthesis. The findings suggest that retaining mental health occupational therapists is a complex issue, affected by many factors. The study emphasizes the triangular relationship among three aspects of well-being (job satisfaction, professional identity and burnout) at work and introduces the concept of a ’Retention Ecosystem’. This illustrates how subtheme factors interconnect and influence the retention of mental health occupational therapists. Conclusion: The retention of mental health occupational therapists is revealed to be a multifaceted challenge. There is a need for developing more targeted, meaningful and holistic strategies for retaining the current mental health occupational therapist workforce.
The Dysregulation of the Glymphatic System in Patients with Psychosis Spectrum Disorders Minimally Exposed to Antipsychotics: La dérégulation du système glymphatique en présence de troubles psychotiques chez des patients peu exposés à des antipsychotiques
Authors: Korann Vittal , Panganiban Kristoffer J. , Stogios Nicolette , Remington Gary , Graff-Guerrero Ariel , Chintoh Araba , Hahn Margaret K. , Agarwal Sri Mahavir 
Published: October 2024

Objective The pathophysiological mechanisms influencing psychosis spectrum disorders are largely unknown. The glymphatic system, which is a brain waste clearance pathway, has recently been implicated in its pathophysiology and has also been shown to be disrupted in various neurodegenerative and vascular diseases. Initial studies examining the glymphatic system in psychosis spectrum disorders have reported disruptions, but the findings have been confounded by medication effects as they included antipsychotic-treated patients. In this study, we used diffusion tensor imaging analysis along the perivascular space (DTI-ALPS) as a technique to measure the functionality of the glymphatic system in a sample of antipsychotic-minimally exposed patients with psychosis spectrum disorders and healthy controls. Methods The study included 13 antipsychotic-minimally exposed (2 weeks antipsychotic exposure in the past 3 months/lifetime) patients with psychosis spectrum disorders and 114 healthy controls. We quantified water diffusion metrics along the x-, y-, and z-axes in both projection and association fibres to derive the DTI-ALPS index, a proxy for glymphatic activity. Between-group differences were analyzed using two-way ANCOVA controlling for age and sex. Partial correlations were used to assess the association between the ALPS index and clinical variables. Results Analyses revealed that antipsychotic-minimally exposed psychosis spectrum disorder patients had a lower DTI-ALPS index value than healthy controls in both hemispheres and the whole brain (all P < 0.005). Significant differences were also observed between the x and y projections/associations between patients and healthy controls ( P < 0.001). Furthermore, we did not find any significant correlations (all P > 0.05) between the DTI-ALPS index with age, body mass index, symptomatology, and metabolic parameters. Conclusion This study shows that the glymphatic system is dysregulated in antipsychotic-minimally exposed patients with psychosis spectrum disorders. Understanding the mechanisms that influence the glymphatic system may help to understand the pathophysiology of psychosis spectrum disorders as proper waste clearance is needed for normal brain functioning.
Determining method of optimal process parameters using Taguchi method and technique for order preference by similarity to ideal solution in plastic injection molding
Authors: Kim Ju Song , Yang Won-Chol 
Published: October 2024

Many plastic injection molding (PIM) process optimization problems are multi-objective optimization problems that optimize multiple mechanical properties. This paper proposed a determining method of optimal process parameters and their effect ranks using Taguchi method and TOPSIS in the PIM. TOPSIS was used to convert multiple mechanical properties into single comprehensive response. It was selected as a reasonable multi-attribute decision-making (MADM) method from among some well-known MADM methods based on mean rank correlation coefficient and mean absolute rank deviation. Taguchi method was used to design experiment and find the optimal process parameters. The proposed method was applied to determine the optimal values of the process parameters: melt temperature (MT), packing pressure (PP), cooling time (CT), and injection pressure (IP) for improving tensile strength, elasticity module, flexural modulus, and impact strength in the PIM with Acrylonitrile-Butadiene-Styrene compound as plastic materials and AISI 1020 as mold materials. The optimal values of the process parameters were MT of 280°C, PP of 28 MPa, CT of 22 s, and IP of 50 MPa, and their effect ranking was IP (51.941%), PP (32.280%), CT (9.045%), and MT (6.734%). The method could be widely applied to not only the PIM process optimization but also various manufacturing process optimization problems.
Outcomes Associated with the use of High Dose Corticosteroids and IL-6 Inhibitors for the Treatment of Acute Respiratory Distress Syndrome Secondary to SARS COV-2
Authors: Milic Tessa , Shah Kieran , Mitra Anish , Stabler Sarah 
Published: October 2024

Background During the COVID-19 pandemic, treatment strategies evolved rapidly. The RECOVERY trial established corticosteroids as the standard care for reducing mortality in COVID-19 patients. However, some critical care clinicians began using doses higher than those recommended in RECOVERY. Objective To characterize the use of high-dose corticosteroids and IL-6 inhibitors in critically ill COVID-19 patients and examine their association with adverse drug events (ADEs). Methods A retrospective cohort study of 320 electronic health records (January 1, 2020 - June 30, 2022) was conducted on COVID-19 patients requiring high-flow oxygen or mechanical ventilation. Patients were categorized based on corticosteroid dose: “high dose dexamethasone” (daily dose greater than 12 mg and/or for longer than 10 days), “low dose dexamethasone” (daily dose 12 mg or less for 10 days or less), and “no dexamethasone” (no corticosteroid therapy). Subgroups were created based on IL-6 inhibitor use. Results High-dose dexamethasone was associated with increased odds of ADEs compared to low dose (OR 2.55, 95% CI 1.45 to 4.49) and no dexamethasone (OR 6.29, 95% CI 2.08 to 19.03). No additional efficacy benefit was observed in patients receiving high dose corticosteroids when compared to low dose corticosteroids. Patients receiving both an IL-6 inhibitor and high-dose dexamethasone had further increased odds of ADEs. High-dose dexamethasone was also associated with increased mortality compared to low dose (OR 3.78, 95% CI 1.97-7.25) and no dexamethasone (OR 15.22, 95% CI 3.27-70.74). Conclusions Acknowledging the risk for residual confounding, higher doses of dexamethasone were associated with increased ADEs and mortality. These findings highlight the need for careful consideration of the use of high-dose dexamethasone.
The Application of Ficus Species in the Treatment of Neurological Disorders
Authors: Alam Adib , Mazumder Papiya Mitra 
Published: October 2024

Background Neurological diseases represent a pressing global health concern; the World Health Organization reports that neurological conditions rank as the second leading cause of death worldwide. In the last quarter century, we have witnessed a remarkable 36% surge in global neurological mortality rates. Several factors, including oxidative stress, genetic variability, natural aging process, inflammation, hypertension, diabetes, infections, vitamin deficiencies, metabolic imbalances, chemical exposures, endocrine disorders, and dietary supplements, are implicated in the initiation and progression of various neurological diseases. Purpose This comprehensive review aims to shed light on the neuroprotective attributes of distinct Ficus and their phytoconstituents that have been harnessed for treating neurological diseases and demonstrating neuroprotective effects. Methods A literature search was conducted to obtain information about the study of neurological disease and their treatment using database and search engine like Google Scholar, Research gate, monograph, reference book, SciFinder, PubMed/Medline, Scopus, and Science Direct. Results Ficus species have exhibited remarkable neuroprotective qualities through various mechanisms of action. Moreover, these plants contain a diversity of bioactive such as flavonoids, polyphenols, terpenoids, tannins, alkaloids, glycosides, sterols, and vitamins that proven effective in enhancing memory, reducing anxiety, increasing neurotransmitter levels, mitigating neurodegeneration, and playing pivotal roles in neuroprotection. Conclusion This review consolidates the promising potential of Ficus species in the treatment of neurological diseases, paving the way for future scientific research in the development of novel herbal neuroprotective medications.