bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Fraud’ and ‘Misleading Commercial Practices’: Modernising the Law of Defects in Consent
Authors: Patti Francesco Paolo 
Published: December 2016

AbstractThe rules provided by the civil codes on defects in consent were designed at a time when the notion of consumer law did not exist and fairness at the pre-contractual stage was not widely considered as a value worthy of protection. Matters have changed radically in the last three decades. The proliferation of rules protecting consumers on a European level, especially through information duties and rights of withdrawal, and the growing impact of general clauses, has led to a fragmentation of domestic contract law. This clash of different sets of rules is particularly conspicuous in the field of unfair commercial practices as the European legislator has not made provision for specific private law remedies for individual consumers in cases of misleading and aggressive commercial practices. This article addresses the particular issue of the applicability of the law of fraudulent misrepresentation to cases of misleading commercial practices. The purpose is to reconsider ‘fraud’ in terms of a defect in consent, in a manner that is both more in line with the modern features of European contract law and better able to counteract new market strategies based on exploiting cognitive weaknesses. The focus is thus put on the relationship between pre-contractual information duties and defective consent, as well as on some insights of law and economics, which demonstrate that ‘consent theories’ or ‘will theories’ cannot provide precise criteria to indicate when a contract should be void. In conclusion, a possible legislative intervention aiming to substitute the rules on fraud for a set of remedies for violation of information duties is discussed.
Investment Bankers in Conflict: The Regime of Inducements in MiFID II and the Member States’ Struggle for Fairness
Authors: Papaconstantinou George A. 
Published: December 2016

AbstractThis article sheds light on the new legal treatment of inducements, under the revised Markets in Financial Instruments Directive, and seeks to address the question whether or not that regime is beneficial for market participants. Inducements constitute a common practice of day-to-day conduct of business by financial institutions. Accordingly, the rules that define their realm of operation are quintessential for both investment firms and investors. The relevant paradigm of conflicts of interest is used. MiFID II has to be implemented only by 3 January 2018. However, the forthcoming regime on inducements derives from gold-plating practices that are already in place in the UK. An examination and assessment of the impact of inducements policy and their adverse effect on retail investors in the UK is an adequate apparatus to draw parallels from. After highlighting the inherent problems of the EU provisions on inducements, an enhanced framework is designed.
Somatic, Endurance Performance and Heart Rate Variability Profiles of Professional Soccer Players Grouped According to Age
Authors: Botek Michal , Krejčí Jakub , McKune Andrew J. , Klimešová Iva 
Published: December 2016

Abstract
This cross-sectional study compared somatic, endurance performance determinants and heart rate variability (HRV) profiles of professional soccer players divided into different age groups: GI (17–19.9 years; n = 23), GII (20–24.9 years; n = 45), GIII (25–29.9 years; n = 30), and GIV (30–39 years; n = 26). Players underwent somatic and HRV assessment and maximal exercise testing. HRV was analyzed by spectral analysis of HRV, and high (HF) and low (LF) frequency power was transformed by a natural logarithm (Ln). Players in GIV (83 ± 7 kg) were heavier (p < 0.05) compared to both GI (73 ± 6 kg), and GII (78 ± 6 kg). Significantly lower maximal oxygen uptake (VO2max, ml•kg-1•min-1) was observed for GIV (56.6 ± 3.8) compared to GI (59.6 ± 3.9), GII (59.4 ± 4.2) and GIV (59.7 ± 4.1). All agegroups, except for GII, demonstrated comparable relative maximal power output (Pmax). For supine HRV, significantly lower Ln HF (ms2) was identified in both GIII (7.1 ± 0.8) and GIV (6.9 ± 1.0) compared to GI (7.9 ± 0.6) and GII (7.7 ± 0.9). In conclusion, soccer players aged >25 years showed negligible differences in Pmax unlike the age group differences demonstrated in VO2max. A shift towards relative sympathetic dominance, particularly due to reduced vagal activity, was apparent after approximately 8 years of competing at the professional level.
Physiological Responses During the Time Limit at 100% of the Peak Velocity in the Carminatti’s Test in Futsal Players
Authors: Floriano Leandro Teixeira , da Silva Juliano Fernandes , Teixeira Anderson Santiago , Salvador Paulo Cesar do Nascimento , Dittrich Naiandra , Carminatti Lorival José , Nascimento Lucas Loyola , Guglielmo Luiz Guilherme Antonacci 
Published: December 2016

Abstract
The aim of this study was to investigate the physiological responses during the time limit at the intensity of the peak velocity of the Carminatti’s test (T-CAR). Ten professional futsal players (age, 27.4 ± 5.8 years, body mass, 78.8 ± 8.5 kg, body height, 175.8 ± 6.8 cm, body fat mass, 14.1 ± 2.6%) took part in the study. The players performed three tests, with an interval of at least 48 hours, as follows: the T-CAR to determine the peak velocity and the maximal heart rate; an incremental treadmill protocol to determine the maximal physiological responses; and a time limit running test at the peak velocity reached in the T-CAR. During the last two tests, a portable gas analyzer was used for direct measurement of cardiorespiratory variables. It was shown that the peak velocity was not significantly different from the maximal aerobic speed achieved in the laboratory (p = 0.213). All athletes reached their maximum oxygen uptake during the time limit test. The maximum oxygen uptake achieved during the time limit test was not different from that observed in the laboratory condition (51.1 ± 4.7 vs. 49.6 ± 4.7 ml·kg-1·min-1, respectively, p = 0.100). In addition, Bland and Altman plots evidenced acceptable agreement between them. On average, athletes took ~140 s to achieve maximum oxygen uptake and maintained it for ~180 s. Therefore, the peak velocity intensity can be used as an indicator of maximal aerobic power of futsal athletes and the time limit can be used as a reference for training prescription.
Physical Performance During Water-Polo Matches: The Effect of the Players’ Competitive Level
Authors: Botonis Petros G. , Toubekis Argyris G. , Platanou Theodoros I. 
Published: December 2016

Abstract
The purpose of the study was to compare playing intensity and performance changes within a water-polo match in players of different competitive levels. High-level (n = 7) and lower-level (n = 7) players performed a progressively increasing speed test of 5 x 200 m swimming and speed corresponding to lactate concentration of 4.0, 5.0 and 10.0 mmol•l-1 was calculated. Repeated sprint ability (8 x 20 m) was tested at pre-, the middle and post-match and a 400 m swimming test was completed at pre and post in five water-polo matches. A t-test and a two-way ANOVA were used for statistical analysis. High-level compared to lower-level players presented higher speed corresponding to lactate concentration of 4.0 and 5.0 mmol•l-1 (p < 0.05). Regardless of the sports level, the mean heart rate was reduced towards the end of the match. High-level players completed a shorter amount of match time with the heart rate lower than 85% of the peak heart rate (p < 0.05). However, when the speed corresponding to lactate concentration of 4.0 mmol•l-1 was used as a covariate, no differences were observed in the heart rate between groups. Both groups decreased repeated sprint and 400 m performance at post- compared to pre-match by 7 ± 3% and 7 ± 4%, respectively. High-level compared to lower-level players showed better performance in repeated sprints at the middle (p < 0.01) and in pre-, post-match 400 m tests (p < 0.01). It was concluded that high-level compared to lower-level players completed the match at a higher playing intensity and presented a lower performance decrement across the match as a result of their higher aerobic endurance.
Performance Assessment in Water Polo Using Compositional Data Analysis
Authors: Ordóñez Enrique García , Pérez María del Carmen Iglesias , González Carlos Touriño 
Published: December 2016

Abstract
The aim of the present study was to identify groups of offensive performance indicators which best discriminated between a match score (favourable, balanced or unfavourable) in water polo. The sample comprised 88 regular season games (2011-2014) from the Spanish Professional Water Polo League. The offensive performance indicators were clustered in five groups: Attacks in relation to the different playing situations; Shots in relation to the different playing situations; Attacks outcome; Origin of shots; Technical execution of shots. The variables of each group had a constant sum which equalled 100%. The data were compositional data, therefore the variables were changed by means of the additive log-ratio (alr) transformation. Multivariate discriminant analyses to compare the match scores were calculated using the transformed variables. With regard to the percentage of right classification, the results showed the group that discriminated the most between the match scores was “Attacks outcome” (60.4% for the original sample and 52.2% for cross-validation). The performance indicators that discriminated the most between the match scores in games with penalties were goals (structure coefficient (SC) = .761), counterattack shots (SC = .541) and counterattacks (SC = .481). In matches without penalties, goals were the primary discriminating factor (SC = .576). This approach provides a new tool to compare the importance of the offensive performance groups and their effect on the match score discrimination.
Optimization of Game Formats in U-10 Soccer Using Logistic Regression Analysis
Authors: Amatria Mario , Lapresa Daniel , Arana Javier , Anguera M. Teresa , Garzón Belén 
Published: December 2016

Abstract
Small-sided games provide young soccer players with better opportunities to develop their skills and progress as individual and team players. There is, however, little evidence on the effectiveness of different game formats in different age groups, and furthermore, these formats can vary between and even within countries. The Royal Spanish Soccer Association replaced the traditional grassroots 7-a-side format (F-7) with the 8-a-side format (F-8) in the 2011-12 season and the country’s regional federations gradually followed suit. The aim of this observational methodology study was to investigate which of these formats best suited the learning needs of U-10 players transitioning from 5-aside futsal. We built a multiple logistic regression model to predict the success of offensive moves depending on the game format and the area of the pitch in which the move was initiated. Success was defined as a shot at the goal. We also built two simple logistic regression models to evaluate how the game format influenced the acquisition of technicaltactical skills. It was found that the probability of a shot at the goal was higher in F-7 than in F-8 for moves initiated in the Creation Sector-Own Half (0.08 vs 0.07) and the Creation Sector-Opponent's Half (0.18 vs 0.16). The probability was the same (0.04) in the Safety Sector. Children also had more opportunities to control the ball and pass or take a shot in the F-7 format (0.24 vs 0.20), and these were also more likely to be successful in this format (0.28 vs 0.19).
Optimization of the Spray-Drying Process for Developing Stingless Bee Honey Powder
Authors: Cuevas-Glory Luis F. , Pino Jorge A. , Sosa-Moguel Odri , Sauri-Duch Enrique , Bringas-Lantigua Madai 
Published: December 2016

Abstract
Response surface methodology was used to optimize the spray-drying process for the development of stingless bee honey powder. The independent variables were: inlet air temperature (110–150 oC) and maltodextrin 10DE content (50–70 % wb). The responses were powder yield, moisture, volatiles retention, solubility time, hygroscopicity, bulk loose, and hydroxymethylfurfural content. Powder moisture content, solubility time, hygroscopicity and loose bulk density were negatively affected by inlet air temperature, while powder yield, volatiles retention and hydroxymethylfurfural content were directly related. Powder yield, volatiles retention and solubility time increased with the rise in maltodextrin content, while moisture content, hygroscopicity, loose bulk density and hydroxymethylfurfural content were negatively affected by maltodextrin content. Multiple response optimization indicated that an inlet air temperature of 150 oC and maltodextrin content of 61 % wb were predicted to provide 40 % powder yield, 4.9 % wb moisture content, 71 % volatiles retention, 242 s solubility time and 232 mg/kg hydroxymethylfurfural content.
Vitamin D supplementation, the metabolic syndrome and oxidative stress in obese children
Authors: Grunwald Tal , Fadia Shruti , Bernstein Bruce , Naliborski Matthew , Wu Shufang , Luca Francesco De 
Published: December 2016

AbstractBackground:Previous studies suggest that vitamin D may play a role in cardiovascular and metabolic health. Oxidative stress has also been implicated in the development of cardiovascular disease. Evidence suggests that vitamin D deficiency may contribute to the occurrence of oxidative stress. This study aimed to determine whether treatment and correction of vitamin D deficiency in obese children led to changes in their metabolic profile, independent of changes in adiposity. In addition, we aimed to determine whether vitamin D deficiency and oxidative stress are causally related in obese children.Methods:In the retrospective arm, chart review identified 32 obese children who experienced normalization of vitamin D deficiency or insufficiency with vitamin D supplementation. We then correlated laboratory and anthropometric data with vitamin D levels. In the prospective arm of the study, urinary 8-isoprostane and hydrogen peroxide were measured before and after correction of vitamin D deficiency/insufficiency and correlated to vitamin D levels in seven patients.Results:In our predominantly Hispanic population of obese children in an urban setting, we demonstrated a cause-effect relationship between vitamin D deficiency and oxidative stress. In contrast, we found no association between vitamin D status, adiposity, and markers of insulin sensitivity, nor any effect of vitamin D treatment on the same parameters.Conclusions:These discordant findings suggest a differential effect of vitamin D on cardiovascular risk factors such as oxidative stress and insulin resistance. To confirm these findings, further prospective studies with larger sample size and longer follow-up are warranted.
Rapid assessment of nonvolant mammals in seven sites in the northern State of Pará, Brazil: a forgotten part of the Guiana Region
Authors: Rossi Rogério Vieira , Miranda Cleuton Lima , Semedo Thiago Borges Fernandes 
Published: December 2016

AbstractThe Guiana Center of Endemism (GCE) extends across Guyana, Suriname, French Guiana, north of the Amazon River and east of the Negro River in Brazil, and Venezuela to the south of the Orinoco River. Regarding diversity of nonvolant mammals, the Brazilian part of this center is less studied, especially the area corresponding to the north of the State of Pará. Seven field trips lasting 12–15 days each were conducted in five conservation units in northern Pará, in order to assess the nonvolant mammalian fauna. Small mammals were captured using conventional and pitfall traps. Medium-sized and large mammals were recorded through direct observations on diurnal transect censuses, collections, camera traps, indirect evidence, and in some cases, interviews. We recorded 60 species distributed in nine orders. Among other contributions, a recently described species of
Membrane protein reconstitution in nanodiscs for luminescence spectroscopy studies
Authors: Zoghbi Maria E. , Altenberg Guillermo A. 
Published: December 2016

AbstractATP-binding cassette (ABC) exporters transport substrates across biological membranes using ATP hydrolysis by a process that involves switching between inward- and outward-facing conformations. Most of the structural studies of ABC proteins have been performed with proteins in detergent micelles, locked in specific conformations and/or at low temperature. In this article, we present recent data from our laboratories where we studied the prototypical ABC exporter MsbA during ATP hydrolysis, at 37°C, reconstituted in a lipid bilayer. These studies were possible through the use of luminescence resonance energy transfer spectroscopy in MsbA reconstituted in nanodiscs. We found major differences between MsbA in these native-like conditions and in previous studies. These include a separation between the nucleotide-binding domains that was much smaller than previously thought, and a large fraction of molecules with associated nucleotide-binding domains in the nucleotide-free apo state. These studies stress the importance of studying membrane proteins in an environment that approaches physiological conditions.
Long-term changes in water quality and ecological status of lakes in the Wielkopolska National Park and its buffer zone with special reference to effectiveness of the lakes’ protection
Authors: Ławniczak Agnieszka E. 
Published: December 2016

Abstract
This paper evaluates water quality and ecological status of lakes located in the Wielkopolska National Park and its buffer zone. Changes in water quality were analyzed from 1974 to 2012 in order to assess the effectiveness of the protection strategies implemented on the studied lakes since 1957, i.e. the date when the park was established. The ecological status of the lakes was assessed with the use of macrophytes as well as hydromorphological and physicochemical analyses performed in 2012. Changes in water quality of the studied lakes within the last 40 years were analyzed based on available published and unpublished data, as well as field studies. All water bodies are characterized by advanced eutrophication. However, evaluation of the ecological status showed good status of the charophyte-dominated lakes, i.e. Lake Wielkowiejskie and Lake Budzyńskie. Lack of significant differences in physicochemical water qualities between the park and its buffer zone indicated that measures implemented to protect the water, particularly in the park, are ineffective. This study shows that more radical conservation measures are necessary to protect and improve the water quality, not only in WPN and its buffer zone but also in the whole catchment area.
The Actuality of the Movable (by the Mover): a Relational Interpretation of Aristotle’s Definition of Motion
Authors: Ugaglia Monica 
Published: December 2016

AbstractThe paper discusses Aristotle’s conception of motion and proposes a new perspective for a reading. Of course, motion can be located between two states of a movable, between potentiality and actuality, but it can also be located between (the state of) a movable and (that of) its mover. It is also argued that this relational perspective is the correct way to understand Aristotle’s definition of motion. When Aristotle defines motion as “the actuality of what potentially is,
Hepatoprotective role of Solenostemma argel growing in Egypt on ethanol induced oxidative damage in rats
Authors: Mohamed Ahmed Mahgoub 
Published: December 2016

Abstract

Objective
The objective of the current study is to investigate the protective effect of Solenostemma argel (S. argel) treatment on ethanol (EtOH)-induced hepatotoxicity in rat liver.

Methods
Forty adult male albino rats were divided into four groups as control, S. argel (100 mg/kg), EtOH (3 g/kg) and S. argel + EtOH groups. S. argel was given 1 h prior to EtOH by oral gavage for 28 days.

Results
The results showed that, administration of EtOH caused a significant decrease (p<0.05) in serum total protein and albumin, whereas ALT and AST and lipid peroxidation (LPO) were increased following EtOH treatment. S. argel treatment significantly (p<0.05) ameliorated the previous parameters. Protein carbonyl, reduced glutathione and LPO levels were significantly (p<0.05) increased along with glutathione-S-transferase activity was decreased (as markers of oxidative stress) in EtOH treated rat liver. Previous oxidative stress was attenuated significantly by S. argel treatment. Moreover, in EtOH group, tumor necrosis factor-α (TNF-α) and nitric oxide (NO) contents and cytochrome P450 2E1 activity were significantly increased in liver tissues showing oxidative organ damage. Co-administration of S. argel with EtOH significantly reversed the inflammation in rat livers.

Conclusion

S. argel had a hepatoprotective role against EtOH-induce oxidative stress and inflammation in rat liver.
Evaluation of laboratory parameters in the diagnosis of acute appendicitis
Authors: Ulukent Suat Can , Şahbaz Nuri Alper , Özyürek Eser Şefik , Sarıcı İnanç Şamil , Akça Özlem , Özgün Mehmet Yiğit , Akbayır Özgür , Kalaycı Mustafa Uygar 
Published: December 2016

Abstract

Introduction
The aim of this prospective study was to investigate the diagnostic value of the fibrinogen level, platelet (PLT) count, mean platelet volume (MPV), lymphocyte count, neutrophil/lymphocyte ratio (NLR) and C-reactive protein (CRP) level with white blood cell (WBC) and neutrophil count in acute appendicitis (AA).

Methods
One hundred and ninety-seven patients who were admitted with the findings of acute abdomen and operated on with a preoperative diagnosis of AA were included in this prospective observational study. After surgery, according to the histopathological results of the appendix, patients were classified as Group 1; with normal histology of appendix vermicularis, Group 2; patients with positive histology for appendicitis with or without perforation, periappendiceal abscess, suppurative, gangrenous or ulcerophlegmonous appendicitis.

Results
In the comparison of the two groups, the difference between CRP and MPV were insignificant (p=0.12 and p=0.09, respectively). WBC, neutrophil count, NLR were significantly higher in Group 2 (p<0.001 for each), whereas fibrinogen levels, lymphocyte count and the PLT counts were significantly higher in Group 1 (p=0.03, 0.002 and 0.003, respectively).

Discussion and conclusion
WBC, neutrophil and NLR are predictive for the diagnosis of AA, whereas elevated levels of fibrinogen, high lymphocyte and PLT count are predictive for non-appendicial pathology with low diagnostic accuracies.