bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFICACY AND SAFETY OF BAN HUANG ORAL LIQUID FOR TREATING BOVINE RESPIRATORY DISEASES
Authors: Li Bing , Zhou Xu-Zheng , Niu Jian-Rong , Wei Xiao-Juan , Li Jian-Yong , Yang Ya-Jun , Liu Xi-Wang , Cheng Fu-Sheng , Zhang Ji-Yu 
Published: March 2017

Background: Ban Huang oral liquid was developed as a veterinary compound preparation by the Lanzhou Institute of
Husbandry and Pharmaceutical Sciences of the Chinese Academy of Agricultural Sciences (CAAS). The purpose of
this study was to determine whether the oral liquid preparation of traditional Chinese medicine, Ban Huang, is safe and
effective for treating respiratory diseases in cattle.
Materials and Methods: Acute oral toxicity experiments were conducted in Wistar rats and Kunming mice via oral
administration. The minimum inhibitory concentration of the drug against Mycoplasma bovis in vitro with the double
dilution method was 500 mg/mL, indicating good sensitivity. The results of laboratory pathogen testing, analysis of
clinical symptoms, and analysis of pathological anatomy were combined to diagnose bovine respiratory diseases in 147
Simmental cattle caused by mixed infections of M. bovis, bovine respiratory syncytial virus, bovine parainfluenza virus
type 3, and Mannheimia haemolytica. These cattle were randomly divided into three groups: drug treatment group 1
(treated via Tilmicosin injection), drug treatment group 2 (treated with Shuang Huang Lian oral liquid combined with
Tilmicosin injection), and drug treatment group 3 (treated with Ban Huang oral liquid combined with Tilmicosin
injection). Treatment effects were observed within 7 days.
Results: The results showed no toxicity and a maximum tolerated dose greater than 20 g/kg BW. For the 87 cattle in
drug-treatment group, the cure rate was 90.80%, whereas the response rate was 94.25%. The cure rate of drug treatment
group was increased by 14.13% in comparison with that of drug control group 1 and by 7.47% in comparison with that
of drug control group 2 (both P < 0.05).
Conclusion: This study demonstrates that Ban Huang oral liquid is a safe and effective treatment for bovine respiratory
diseases, especially for mixed infection caused by M. bovis, bacteria, and viruses.
COGNITIVE-ENHANCING PROPERTIES OF MORINDA LUCIDA (RUBIACEAE) AND PELTOPHORUM PTEROCARPUM (FABACEAE) IN SCOPOLAMINE-INDUCED AMNESIC MICE
Authors: Taiwo O Elufioye , Halimah A. Hameed 
Published: March 2017

Background: Cognitive disorders associated with aging have been successfully managed by African traditional
medical practitioners using various plants. This study evaluated the cognitive enhancing potentials of Morinda lucida
(L) Rubiaceae and Peltophorum pterocarpum (DC) ex. K Heyne in scopolamine induced amnesic animals.
Materials and Methods: The anti-amnesic activity of the ethyl acetate extracts of Morinda lucida and Peltophorum
pterocarpum at doses of 4 mg/kg, 6 mg/kg and 8 mg/kg were assessed in scopolamine induced amnesic mice using
Morris water maze test model. Effect of the extracts on the histology of the hippocampus was also evaluated.
Results: The ethyl acetate extract of Morinda lucida and Peltophorum pterocarpum ameliorated scopolamine induced
memory deficit in the animals under study. There was no effect of the extract on the histology of the hippocampus.
However, there was an increase in the density of cells in the hippocampus of treated group as compared to the
untreated.
Conclusion: Morinda lucida and Peltophorum pterocarpum showed considerable enhancement of cognition in
scopolamine induced amnesic mice.
IN VITRO CHEMO-PREVENTATIVE ACTIVITY OF STRELITZIA NICOLAI ARIL EXTRACT CONTAINING BILIRUBIN
Authors: Dwarka Depika , Thaver Veneesha , Naidu Mickey , Koorbanally Neil A. , Baijnath Himansu 
Published: March 2017

Background: The discovery of the only animal pigment, bilirubin, in the plant Strelitzia nicolai has triggered a vast
number of questions regarding bilirubin’s formation and its role in the human body. Recent studies have confirmed that
bilirubin at certain levels have many medical benefits. Various case studies have revealed that bilirubin is a potent
antioxidant. Cervical cancer is one of South Africa’s largest womens’ health crises. It is estimated that it affects one out
of 41 South African women and kills approximately 8 women in the country every day. Thus, the aim of this study was
to investigate if the aril extract of Strelitzia nicolai (Regel and Körn.) containing bilirubin possesses anti-cancer activity
and to determine its effect on the induction of apoptosis.
Materials and methods: The DPPH activity was firstly used to determine the antioxidant effect of the extract.
Thereafter, the cytotoxic effect was tested using the XTT assay. Apoptosis was confirmed and quantified using the
Annexin V-PE kit and the morphology was studied using acridine orange and ethidium bromide. Results: The aril
extract decreased cell viability by 52% and induced apoptosis in HeLa cells; as shown by the Annexin V-PE Apoptosis
detection kit and morphological studies with acridine orange/ethidium bromide staining. Conclusion: The activity of
the extract as a potent antioxidant was immensely enhanced as compared to the bilirubin standard. These results
suggest that S. nicolai aril extract containing bilirubin works synergistically as opposed to bilirubin on its own.
Furthermore, this extract might be a good candidate for the therapeutic intervention of cervical cancer.
STUDIES ON CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITIES OF BIOACTIVE MOLECULES FROM DATE PALM (PHOENIX DACTYLIFERA L.) POLLENS AND SEEDS
Authors: Bentrad Najla , Gaceb-Terrak Rabéa , Benmalek Yamina , Rahmania Fatma 
Published: March 2017

traditions as alternative medicines. The chemical profiling of some plant extracts and essential oils related to different
plants were followed to unveil their most active components. In this paper, Phoenix dactilyfera L was selected as a host
plant to investigate the composition of different organs with different cultivars.
Materials and method: The antibacterial and antifungal activities of the extracts have been tested using different
techniques, including optical density and GC/MS analyses of the natural extracts.
Results: GC/MS analysis revealed the presence of abundant oleic (36.69%) and lauric (20.49%) acids in date seeds.
However,the pollen contains a high amount of palmitic (22.27 %), linoleic (33.4%) and linolenic (17.055%) acids.
Moreover, the largest inhibition zone is obtained with the organic extract of Deglet Nour which showed a strong
antibacterial activity against Escherichia coli and pollen extract showed also a strong inhibition against Escherichia
coli, Staphylococcus aureus, S. aureus MRSA and Enterococcus faecalis. Aqueous extracts of date palm seeds of and
pollen seem to have a fongitoxique activity from a concentration of 6 mg.mL-1 and 12mg.mL-1 of cyanidine; as well as
the organic extracts of pollen with a concentration of 90 μg.mL-1 induce an inhibition to the growth of five special
forms of Fusarium oxysporum.
Conclusion: The bioactive compounds of date palm can be used for drug development and in the food industry.
PREPARATION AND PROPERTIES OF COMPOUND ARNEBIAE RADIX MICROEMULSION GEL
Authors: Chen Jing , He Yanping , Gao Ting , Zhang Licheng , Zhao Yuna 
Published: March 2017

Background: Compound Arnebiae radix oil has been clinically applied to treat burns and scalds for a long time.
However, it is unstable and inconvenient to use. The aim of this study was to prepare a compound Arnebiae radix
microemulsion gel for transdermal delivery system and evaluate its characteristics.
Materials and Methods: Based on the solubility of Shikonin, the active component of Arnebiae radix and the results
of phase studies, adequate ratio of each component in microemulsion was determined. The optimized microemulsion
gel was prepared using Carbomer 940. The gels were characterized in terms of appearance, preliminary stability test
and the content of Shikonin in the compound Arnebiae radix microemulsion gel with HPLC analysis.
Results: The optimized conditions for preparing microemulsion were Tween-80, glycerin, isopropyl myristate (IPM)
with the ratio of 6:3:2. The optimal microemulsion gel was obtained with Carbomer 940 (1.0%).
Conclusion: The prepared compound Arnebiae radix microemulsion gel showed good stability over time. It is more
convenience in application than the previous used formulations.
EVALUATION OF CRUDE FLAXSEED (Linum usitatissimum L.) OIL IN BURN WOUND HEALING IN NEW ZEALAND RABBITS
Authors: Beroual Katiba , Agabou Amir , Abdeldjelil Mohamed-Cherif , Boutaghane Naima , Haouam Saïd , Hamdi-Pacha Youcef 
Published: March 2017

Background: Burns are among the most prevalent injuries in humans with high cost in health care and heavy
prolonged or permanent physical, psychological and social consequences. Commercial antimicrobial creams and
dressing agents are unsuccessful in healing deep burn wounds.
Materials and Methods: A study was conducted to assess the impact of crude linseed oil (LSO) topical application on
burn wounds healing in rabbits in comparison with untreated wounds (NAT) and those treated with Vaseline gel
(VAG) and Cicatryl-Bio ointment (CBO). By the 28th day post burning, skin biopsies were analyzed for histological
and cytological lesions. The presence of various bioactive phytochemical groups in linseed was also screened.
Results: Phytochemical screening has resulted in high concentrations of flavonoids and terpenoids, low amounts of
catechic tannins and total absence of alkaloids and saponosides. All along the trial, the rate of wounds contraction was
found to be significantly higher in burns treated with LSO which had also a significant shorter healing period (26±5.89
days) as compared to the other treatments. LSO healed wounds included less inflammatory cells, complete epithelium
regeneration with a reduced thickness of the new formed dermis, discreet fibrosis, enhanced neo-vascularization,
increased number of collagen fibers, fibroblasts and many myofibroblasts. Additionally, no adverse effects of LSO on
cicatrization process were recorded.
Conclusion: These findings prove the safety and efficaciousness of linseed oil topical application in the therapy of
burn wounds.
ANTI-DIABETIC EFFECTS OF ZHUODUQING FORMULA, A CHINESE HERBAL DECOCTION, ON A RAT MODEL OF TYPE 2 DIABETES
Authors: Feng Xiao-Tao , Tang Shu-Yan , Jiang Yun-Xia , Zhao Wei 
Published: March 2017

Background: Zhuoduqing formula (ZDQ) is a Chinese herbal decoction and used to treat type 2 diabetes in clinical
practice, but the potential evidence needs to be provided.
Materials and Methods: Type 2 diabetic model rats were induced by feeding high fat diet (HFD) and intraperitoneal
injection of streptozotocin (STZ). The model rats were given ZDQ for 4 weeks. Insulin sensitivity was evaluated by
homeostasis model assessment of basal insulin resistance (HOMA-IR) and intraperitoneal glucose tolerance test
(IPGTT). Blood insulin and tumour necrosis factor-α (TNF-α) levels as well as SOCS-3 levels in skeletal muscles were
analyzed by ELISA.
Results: ZDQ significantly decreased fasting blood glucose, ameliorated HOMA-IR and IPGTT, and reduced
triglyceride and total cholesterol in type 2 diabetic rats. Moreover, ZDQ remarkably lowered blood TNF-α levels and
inhibited SOCS-3 levels in skeletal muscles.
Conclusion: The results display that ZDQ performs anti-diabetic functions in type 2 diabetic rats induced by feeding
HFD and intraperitoneal injection of STZ.
EFFECTS OF AROMATHERAPY MASSAGE ON THE SLEEP QUALITY AND PHYSIOLOGICAL PARAMETERS OF PATIENTS IN A SURGICAL INTENSIVE CARE UNIT
Authors: Özlü Zeynep Karaman , Bilican Pınar 
Published: March 2017

Background: Surgical pain is experienced by inpatients with clinical, disease-related concerns, unknown encounters
after surgery, quality of sleep, restrictions in position after surgery is known to be serious. The study was conducted to
determine the effect of aromatherapy massage on quality of sleep and physiological parameters in surgical intensive
care patients.
Materials and Methods: This is an experimental study. The sample of this study consisted of 60 patients who were
divided into two groups as experimental group and control group including 30 patients in each one. The participants
were postoperative patients, absent complications, who were unconscious and extubated. A data collection form on
personal characteristics of the patients, a registration form on their physical parameters and the Richards-Campbell
Sleep Scale (RCSQ) were used to collect the data of the study.
Results: The Richards-Campbell Sleep Scale indicated that while the experimental group had a mean score of 53.80 ±
13.20, the control group had a mean score of 29.08 ± 9.71 and there was a statistically significant difference between
mean scores of the groups. In a comparison of physiologic parameters, only diastolic blood pressure measuring
between parameters in favor of an assembly as a statistically significant difference was detected.
Conclusions: Results of the study showed that aromatherapy massage enhanced the sleep quality of patients in a
surgical intensive care unit and resulted in some positive changes in their physiological parameters.
El nuevo patrón de crecimiento de China y los posibles impactos en su relación con la Comunidad de Estados Latinoamericanos y Caribeños (CELAC)
Authors: Emmerich Norberto , Reis Marcos 
Published: March 2017

El documento analiza la relación económica entre China y la Comunidad de Estados Latinoamericanos y Caribeños (CELAC) ante la desaceleración y cambios estructurales de la economía china. El nuevo escenario de crecimiento de China, basado en una menor inversión y mayor demanda interna, trae retos y desafíos para esta articulación. En especial, puede representar una oportunidad para una relación más “tradicional Sur-Sur” con un déficit comercial más pequeño y menos dependencia de las exportaciones de materias primas para la región de América Latina y el Caribe. El artículo concluye que con el fin del auge de las materias primas. La relación económica existente entre los miembros de la CELAC y China tiene que cambiar debido a las nuevas perspectivas de crecimiento de China. La CELAC tiene que tener esto en cuenta y preparar una agenda que pueda fortalecer los compromisos y beneficiarse de las oportunidades que van a surgir en virtud de los profundos cambios económicos en China.
Ações Socioeducativas como Práticas de Inovações Sociais: Um Estudo de Caso
Authors: Schutz Evandro , Picolli Icaro , Sehnem Simone , Nunes Nei Antônio 
Published: March 2017

<p>O presente estudo procura analisar se as ações socioeducativas desenvolvidas pelo Instituto Engevix podem ser consideradas práticas de inovações sociais. A pesquisa consiste em um estudo de caso desenvolvido junto aos informantes-chaves e beneficiados do projeto, totalizando 35 participantes. Também foram abordadas visões teóricas das concepções de ações socioeducativas e inovações sociais, buscando detectar os possíveis elos entre elas. Ao analisar se as ações socioeducativas podem ser consideradas inovações sociais os entrevistados responderam afirmativamente, acrescentando que os serviços oferecidos pelo Instituto Engevix não estavam disponíveis até a sua chegada na comunidade. O Instituto Engevix desenvolve ações inclusivas e atende a uma parcela da comunidade em situação de vulnerabilidade econômico-social. De modo geral, tanto as ações socioeducativas quanto as práticas de inovações sociais auxiliam no processo de desenvolvimento social. Vê-se que podem existir como dois processos independentes, embora possam ocorrer convergência e fusão entre eles, ou seja, um projeto socioeducativo pode tornar-se total ou parcialmente uma prática de inovação social. A investigação evidencia que mesmo não sendo original, o projeto socioeducativo promovido pelo Instituto Engevix se configura numa prática de inovação social, pois contribui para a inclusão social dos sujeitos que dele participam. Constata-se, contudo, com o aprofundamento teórico da pesquisa que há, no projeto, um aspecto dissonante em relação às linhas definidoras de uma prática de inovação social. Trata-se da ausência de uma participação mais autônoma e ativa da comunidade assistida nos rumos e decisões tomados pelo projeto. Por fim, o interesse por desenvolver este estudo na área de inovações sociais está ancorado, sobretudo, na possibilidade de gerar compreensão de problemas de gestão social candentes nas sociedades contemporâneas.</p> <p> </p>
Capital Humano e Desenvolvimento Econômico no Rio Grande do Sul: Uma Abordagem Multivariada
Authors: Costa Nilson Luiz , Costa Viviane Ottonelli , Mattos Carlos André Corrêa de , Teixeira Olívio Alberto , Flores Antônio Joreci , Oliveira Gabriel Nunes de 
Published: March 2017

<p>Este artigo propõe uma análise a partir das teorias que associam o capital humano ao processo de desenvolvimento econômico. O método utilizado é composto por técnicas de estatística multivariada, principalmente a Análise Fatorial Exploratória e Análise de Conglomerados. Foram selecionadas estatísticas dos 496 municípios do Estado do Rio Grande do Sul de acordo com sua capacidade de explicar as dinâmicas de concentração de renda, qualidade da educação e saúde, pobreza, educação e trabalho formal. Entre os resultados, destaca-se a associação positiva e direta entre os níveis de educação formal e de desenvolvimento econômico, o que valida as contribuições teóricas de Theodore William Schultz e demais autores que derivam de sua linhagem. Os resultados apontam para a importância de romper os paradigmas atuais e pensar a política educacional para além da retórica dos discursos oficiais e superar os desafios contemporâneos.</p>
KEBERHASILAN PROGRAM DESA VOKASI TERHADAP PEMBERDAYAAN MASYARAKAT DI DESA GEMAWANG KABUPATEN SEMARANG
Authors: Malik Abdul , Dwiningrum Siti Irene Astuti 
Published: March 2017

Penelitian ini bertujuan mengungkapkan keberhasilan program desa vokasi terhadap pemberdayaan masyarakat berkaitan dengan: (1) pelaksanaan; (2) hasil (3) dampak; (4) faktor pendukung dan penghambat program. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Subjek penelitian adalah tim pengembang desa vokasi, kepala desa, ketua dan peserta program. Pengumpulan data melalui: wawancara; observasi; dan dokumentasi. Teknik analisis data melalui: reduksi data; penyajian data; dan penarikan kesimpulan. Hasil penelitian mengungkapkan: (1) Pelaksanaan program desa vokasi melalui: seleksi wilayah, sosialisasi dan pembentukan pengurus, identifikasi dan pembentukan kelompok, pemilihan ketua kelompok, pelaksanaan diklat, dan pertemuan antar kelompok; (2) Hasil program berupa peningkatan kecakapan vokasi dan perkembangan kelompok usaha; (3) Dampak program berupa peningkatan ekonomi, status sosial dan perubahan budaya; (4) Faktor pendukung internal adalah tingginya target meningkatkan kualitas hidup, dan faktor pendukung eksternal ialah kuatnya komitmen aparat desa dan adanya pembinaan instansi terkait. Faktor penghambat internal adalah rendahnya motivasi. Faktor penghambat eksternal adalah cuaca, terbatasnya modal serta banyaknya pesaing dalam pemasaran.Kata Kunci: program desa vokasi, pemberdayaan masyarakat. THE SUCCESS OF THE VOCATIONAL PROGRAM FOR COMMUNITY EMPOWERMENT IN GEMAWANG VILLAGE, SEMARANG REGENCYAbstractThis study aims to reveal the perception the success of vocational to community empowerment about: (1) Implementation; (2) Results; (3) The impact; and (3) supporting and inhibiting factors the program.The study employed the qualitative descriptive approach. The research subjects comprised the team developing the vocational village, the village chief, the head of the program. The data were collected through: interviews, observations, documentation. The data were analyzed through the stages of data reduction, data display, and conclusion drawing or verification. The study reveals the following findings: (1) Implementation the Vocational Village Program through several steps including page region selection, socialization, identification and determination of the group, election of the chairman, the implementation of vocational education and training, vocational group; (2) Output rural vocational program consisting of an increase in vocational skills for each member of the group and the development of business groups; (3) Impact of the vocational village program is the increased economic, social status and cultural; (4) Internal supporting factor is the presence of the ideals of the program participants to achieve a better life, and external contributing factors is the strong commitment by village officials, and special group. While the internal limiting factor is the lack of motivation. External limiting factor is the state of the weather, the limited capital and many competitors in marketing.Keywords: vocational village program, community empowerment
Peranan dongeng dalam pendidikan karakter pada taman kanak-kanak Lazuardi Kamila di Surakarta
Authors: Nuryanto Sidik , Izzaty Rita Eka 
Published: March 2017

Tujuan penelitian untuk mengetahui (1) pelaksanaan pendidikan karakter melalui dongeng, (2) nilai karakter yang dikembangkan, (3) faktor pendukung dan penghambat, dan (4) hasilnya pada TK Lazuardi Kamila. Pendekatan penelitian menggunakan Penelitian kualitatif dengan metode studi kasus. Hasil penelitian yaitu (1) Pelaksanaan dongeng dimulai dengan perencanaan, pelaksanaan dan evaluasi. (2) Nilai karakter meliputi olah hati, olah pikir, olah raga, dan olah rasa. (3) Faktor pendukung lembaga adanya progam mendongeng, sentra Islamic character building, serta penyediaan fasilitas, dan dari pendidik adalah keteladanan. Dukungan orangtua berupa kemudahan komunikasi dengan pihak lembaga. Faktor penghambat lembaga yaitu karyawan belum bisa menjadi teladan, minimnya media dongeng, serta penilaian belum tersusun sistematis. Pendidik belum menyusun daftar dongeng, kesulitan mencari bahasa, dan penjelasan nilai karakter tidak utuh. Orangtua belum bisa menjadi teladan, dan rendahnya partisipasi dalam melanjutkan pendidikan karakter. (4) Hasilnya semua nilai karakter telah dilakukan, kecuali kepemimpinan dan cinta tanah airKata Kunci: dongeng, pendidikan karakter, taman kanak-kanak The Role of Tales in Character Education in Kamila Lazuardi Kindergarten in SurakartaAbstractThe aim of research to determine (1) the implementation of character education through tales, (2) the value of the characters are developed, (3) enabling and inhibiting factors, and (4) the results on TK Lazuardi Kamila. The qualitative research with case study method. Results of the study are (1) The tales begins with the planning, implementation and evaluation. (2) Value of characters includes careful though, if thought, sport, and if the flavor. (3) Factors supporting institutions for programs of storytelling, character building Islamic centers, and the provision of facilities, and from educators is exemplary. Parental support in the form of ease of communication with the institutions. Inhibiting factors, namely agency employees cannot serve as an example, the lack of media stories, as well as the assessment has not been systematically arranged. Educators have not compiled a list of fairy tales, having trouble finding the language, and explanation of the value of the character is not intact. Parents cannot be exemplary, and low participation in continuing education of character. (4) The results of all grades of character has been done, except leadership and patriotism.Keywords: tale, character education, kindergarten